key: cord-0806184-8xmkpzib authors: Almarhapi, Salha Ali; Khalil, Tahani Ahmed title: Depression among healthcare workers in North West Armed Forces hospital-Tabuk, Saudi Arabia: Prevalence and associated factors date: 2021-08-05 journal: Ann Med Surg (Lond) DOI: 10.1016/j.amsu.2021.102681 sha: 72a76313ff726bfef2095b9b595cc59799c37c93 doc_id: 806184 cord_uid: 8xmkpzib BACKGROUND: Depression among healthcare workers results in adverse effects which might include impairment of work performance, reduced productivity and increase in the employee turnover rate. Despite of that, few published studies have been cited concerning depression among hospital healthcare workers in the Kingdom of Saudi Arabia. This study aims to estimate the prevalence and identify the determinants of depression among health care workers working at North West Armed Forces hospital in Tabuk city, KSA. METHODS: This is a cross-sectional study design that was adopted to include a representative sample of physicians and nurses working at North West Armed Forces hospital throughout the study period, provided that they worked at this hospital for at least 6 months. A self-administered questionnaire was applied including three parts; the socio-demographic characteristics of the participants, factors that could be associated with depression and the patient health-9 questionnaire to diagnose depression. RESULTS: The study included 255 healthcare workers. Females represent 58.8 % of the participants. Their age ranged between 22 and 50 years (30.6 ± 5.3 years). About two-thirds of them were nurses (64.3 %) and the remaining 35.7 % were physicians; mainly registrars (22.8 %). The prevalence of depression was 43.9 %. being severe among 0.8 % of them. Results of multivariate logistic regression analysis revealed that HCWs who lost beloved person in the last 6 months were at 3.67 higher risk for developing depression compared to those who didn't report such history (adjusted odds ratio = 3.67; 95 % confidence interval (CI) = 1.84–7.30, p < 0.001). Compared to HCWs of less than 5 years of experience, those with higher experience (5–10 and > 10 years) were at lower significant risk to develop depression (AOR = 0.16; 95 % CI = 0.07–0.037, p < 0.001 and AOR = 0.05; 95 % CI = 0.01–0.029, p = 0.001), respectively. CONCLUSION: Depression is a relatively common health problem affecting healthcare workers in North West Armed forces hospital, Tabuk. However, in majority of cares, the depression was mild. Depression is a mental illness characterized by depressed mood, loss of interest or pleasure, decreased energy, feelings of guilt or low selfworth, disturbed sleep or appetite, and poor concentration" and considered the commonest mental health problem [1] . The World Health Organization (WHO) reported that depression is the leading cause of disability for both genders [2] . Furthermore, it is one of the leading causes of mortality and morbidity worldwide, responsible for 4.4 % of the global disability [3] . According to the WHO, depression is a result of complex interaction of biological, psychological and social factors [4] . Gender is a risk factor regarding prevalence of depression, with higher rates among females compared to males, due to factors associated with social roles or hormonal imbalance, associated with menstruation, childbirth, and menopause [5] . Numerous studies have documented the prevalence and potential causes of depression in healthcare workers either physicians or nurses [6] [7] [8] [9] [10] . According to these studies, healthcare workers have an increased risk of depressive symptoms compared to the general population, mostly due the stressful nature of their work [11, 12] . A systematic review and meta-analysis included studies from 15 countries revealed that the prevalence of depressive symptoms among physicians ranged from 20.9 to 43.2%with a pooled estimate of 28.8 % [13] , while in another systematic review and meta-analysis of studies conducted among intensive care unit nurses, the pooled prevalence of depression was 12 % [14] . Adverse effects of depression on the affected healthcare workers might include impairment of work performance, reduced productivity and increase in the employee turnover rate [15] . Also, it could negatively affect the quality of provided care to patients [11] . Furthermore, depression can result in higher rates of suicidal attempts among healthcare workers as among physicians, the rate of suicide was 1.4 for male and 2.3 for female higher compared to the general population [16] . Nowadays, healthcare workers are on the front line fighting against COVID-19 pandemic as they directly involved in the diagnosis, management, and care of patients, putting them at higher risk of mental health problems, particularly depression as a result of overwhelming workload, widespread media coverage of the situation, shortage of personal protection equipment, lack of specific drugs, and feelings of being inadequately supported and at higher risk for getting the infection than others [17] . Few published studies have been cited concerning depression among hospital healthcare workers in the Kingdom of Saudi Arabia (KSA) with no one from Tabuk city. Therefore, the present study was carried out to assess the magnitude and predictors of depression among this population where the findings could have public health significance for higher authorities. This is a cross-sectional study design which was carried out in Tabuk City. It is located 2200 feet above sea level and has a population of 657,000 according to the last estimation done in 2020 [18] . North West Armed forces hospital (NWAFH) is a tertiary care hospital with a capacity of 332 beds, where the study was specifically carried out. All physicians (n = 484) and nurses (n = 1232) working at NWAFH throughout the study period were eligible for inclusion in the study, provided that they worked at this hospital for at least 6 months. Using Roasoft online sample size calculator with the assumptions that the total population are 1716 physicians and nurses. Prevalence of symptoms of depression among healthcare workers was assumed to be 11.4 % based on the literature [19] with a Confidence Interval (CI) of 99 % with 5 % margins of errors. Accordingly, the calculated sample size was determined to be 232. Stratified random sampling technique with proportional allocation was adopted to select participants according to their job either physicians or nurses. A total of 72 physicians and 183 nurses were invited to participate in the study. Simple random technique was used through preparation of two separate lists of physicians and nurses and selection of the participants from these two lists using the random table generator website. A self-administered questionnaire was utilized for collecting data. It included three parts; the socio-demographic characteristics of the participants (age, gender, nationality, marital status, job title, specialty and satisfaction with salary), the factors that could be associated with depression such as history of chronic diseases, smoking, loss of beloved person within the last 6 months, body mass index (BMI), duration of work in the current facility, working in night shifts and family history of depression and the PHQ-9 questionnaire (Arabic and English versions) which composed of 9 statements. It was a multipurpose instrument used for screening, diagnosing, monitoring and measuring the severity of depression. It incorporates DSM-IV depression diagnostic criteria with others major depressive symptoms into a brief self report instrument and has 61 % sensitivity and 94 % specificity in adults [20] [21] [22] . The PHQ-9 has 9 statements with a score ranging from 0 to 3 for each statement (total score ranging from 0 to 27). The provisional diagnoses of depression, based on the total score was described by Liu et al. as follows: 0-4: no diagnosis, 5-9 mild depression, 10-14 moderate depression, 15-19 moderately severe depression and 20-27 as severe depression [21] . PHQ-9 is available free online; however, permission to use the Arabic version was requested from the corresponding author. The questionnaires were distributed electronically by the researcher herself on all physicians and nurses by Whatsapp app groups. Before beginning of data collection, the questionnaire was pre-tested on approximately 10 % of the sample to ensure that the wording, format, and sequencing of questions are appropriate. Results from the pilot study were included in the final draft as there was no significant difference. Permissions from the program of Family Medicine at Tabuk and local Research and Ethics committee at NWAFH was obtained prior to study conduction. Additionally, permission was sought from the director of the NWAFH, and an informed consent was obtained from all the participants after describing the aim of the study. Statistical Package for Social Sciences (SPSS) software version 26.0 was utilized for data entry and analysis. Descriptive statistics (number, percentage for categorical variables and mean, standard deviation and range for continuous variables) and analytic statistics using Chi Square tests were applied. P-value ≤ 0.05 was considered statistically significant. By considering depression as a dichotomous variable, multivariate logistic regression analysis was done to identify factors associated with depression among healthcare staff at NWAFH-Tabuk after controlling for confounders. The adjusted measure of association between risk factors and depression among them was expressed as the odds ratio (OR) with 95 % Confidence Interval (95 % CI). Adjusted or crude ORs with 95 % CI that did not include 1.0 were considered significant. This study was reported using the Strengthening the reporting of cohort studies in surgery (STROCSS) checklist [23] . The research was registered in Research Registry with registration ID: researchregistry6940. The study included 255 healthcare workers. Their sociodemographic characteristics are summarized in Table 1 . Females represented 58.8 % of the participants while the age ranged between 22 and 50 years with a mean value of 30.6 ± 5.3 years. More than two-thirds were Saudi nationals (69.4 %) and about two-thirds of the total Prevalence of depression among healthcare workers was 43.9 %; being moderately severe and severe among 1.2 % and 0.8 % of them, respectively (Fig. 1) . The highest age reported among participants with mild depression was 31.5 ± 5.7 while the lowest age was observed among those with moderately severe/severe was 26.6 ± 2.1, p = 0.048. Moderately severe and severe depressions were more observed among Saudi participants compared to non-Saudis with 13.6 % and 7.7 %, respectively (p = 0.033). Almost a quarter (23.1 %) were ex-smokers compared to 45 % of non-smokers and 51 % of current smokers were depressed. Furthermore, moderately severe and severe depression were reported among 2.8 % of non-smokers compared to none of current/exsmokers. The overall association between smoking status and depression was statistically significant (p = 0.041). More than half (51.6 %) of HCWs who had work experience less than 5 years were depressed compared to 35.7 % with experience exceeding 10 years reporting depression. Also, 17.4 % of those whose work experience was <5 years expressed moderately severe/severe depressions compared to none for those whose experience exceeded 10 years (p = 0.018). About twothirds (61.1 %) of HCWs with history of chronic diseases had depression compared to 41.1 % of those with no such history. More than a quarter (27.8 %) of those with history of chronic diseases had moderate depression while 9.1 % of those without history of chronic diseases had moderate/moderately severe/severe depression (p = 0.001). About twothirds (67.3 %) of those with history of losing beloved person in the last 6 months were depressed compared to only 37.9 % of those without such history. Additionally, 3.8 % of those with history of losing beloved person in the last 6 months were moderately severe/severe depressed compared to only 1.5 % of those without such history (p < 0.001) ( Table 3) . Results of multivariate logistic regression analysis revealed that HCWs who lost beloved person in the last 6 months were at 3.67 higher risk for developing depression compared to those who didn't report such history (adjusted odds ratio "AOR": 3.67; CI 95 %: 1.84-7.30, p < 0.001). Compared to HCWs of less than 5 years of experience, those with higher experience (5-10 and > 10 years) were at lower significant risk to develop depression (AOR:0.16; 95 % CI 95 %: 0.07-0.037, p < 0.001 and AOR:0.05; CI 95 %:0.01-0.029, p = 0.001), respectively. Age, nationality, smoking history and history of chronic diseases were not significantly associated with depression (Table 4 ). As a result of the nature of the healthcare providers' working environment, they are at higher risk to develop depression [12, 15] . Depression leads to disability among them which in turn, leads to functional impairment in both their workplace and personal lives. Additionally, depression of HCWs c could result in deterioration in patient care, if is manifested within the healthcare setting. Despite of this, relatively limited studies have been cited concerning depression among hospital healthcare workers in Saudi Arabia. Therefore, the present study was conducted to explore the prevalence and determinants of depression among health care workers (physicians and nurses) working at military hospital in Tabuk city. In the current study, the prevalence of depression, based on PHQ-9 questionnaire, was 43.9 %; being mild, moderate, moderately severe and severe among 56.1 %, 32.2 %, 1.2 % and 0.8 % of them, respectively. Furthermore, the prevalence of depression among physicians and nurses were 50 % and 40.9 %, respectively with no significant difference. Local and international studies carried out everywhere reported variable figures. In National Guard hospital in Riyadh, the prevalence of major depressive disorder was 6.7 % and symptoms of depression was 11.4 % [19] . In Egypt, the prevalence of depressive symptoms among all HCWs was 71.4 % [24] . in Iraq, the overall prevalence of probable depressive symptoms was 70.2 % [25] . In Tunisia, 30.5 % of the medical residents had definite whereas 31.5 % had probable depression symptoms [26] . In Malaysia, the prevalence of depression among primary healthcare workers was 38 %; being moderate to severe among one-third of them [27] . In Pakistan, prevalence of mild to moderate depression among hospital physicians was 24.8 % while it was severe among 1.0 % of them [28] . In another study carried out in Pakistan, the prevalence of depression among nurses was 69.4 % [9] . In Nigeria, the prevalence of depression was 17.3 % in resident physicians and 1.3 % in non-resident physicians [29] . In Taiwan, the prevalence of depression was 13.3 % among physicians [30] . In Austria, the prevalence of major depression among physicians was 10.3 % [31] . In Croatia, using the Beck Depression Inventory II (BDI-II), he prevalence of moderate and severe depression among physicians was 12.2 % [32] . In Australia, prevalence rate of depression among nurses was 32.4 % [10] . Variation clearly observed between the studies, including the present one could be attributed partially to difference in the nature of the target population, different methodological approaches as well as different tools used to diagnose depression. Therefore, comparison between them is not practical. In this study, the low experienced healthcare workers were at higher risk for depression compared to more experienced ones. The same has been documented by others [19] . Variable channels faced at the new work environment could explain this depression among lower experienced HCWs. However, some others observed that more experienced nurses were more depressed [24, 28] . As expected, HCWs who reported Table 3 Factors associated with depression among healthcare workers, NorthWest Armed forces hospital, Tabuk. loss of beloved persons in the last 6 months were at higher risk for depression in the current study, even after controlling for confounders. This factor was not investigated among risk factors of depression of healthcare workers in the studies included in literature, despite its importance. In agreement with other studies, no gender difference was reported in the current study regarding the prevalence of depression [29, 30] . However, studies in Egypt [24] and Tunisia [26] reported that females were at higher risk for depression compared to males and attributed this to the differences between the natures of genders, job roles and psychological coping skills between male and female healthcare workers. On the other hand, some others reported that males were at higher risk for depression than females [27] . In some studies, insufficient salary was a predictor for depression among healthcare workers [9, 24] . In the current study, salary was not a significant predictor for depression among the respondents, probably relatively sufficient salary was offered to healthcare workers in Saudi Arabia, although a considerable proportion (45.5 %) of healthcare workers were not satisfied with their salary in the present study. The present study revealed no role of healthcare worker' marital status in depression. The same has been observed by others [29] . Contrary to that, some others reported that married healthcare workers were more likely to have depression [24] , and some reported that singles were more likely to have depression [19] . In the present study, working in night shifts was not associated with depression. In another study carried out in Tunisia, resident physicians with a greater number of night shifts per month were more depressed [26] . Also, in Taiwan, physicians being on more night duty per month were more likely to be depressed [30] . The present study has some important limitations that should be addressed. It included only healthcare workers working at military hospital in Tabuk (single-centre study), so, the generalization of the results should be interpreted with caution. As a result of the crosssectional nature of the study, it is difficult to establish causality between depression and its associated factors. Finally, some important factors that might be related to depression were not investigated in this study such as job satisfaction and detailed work-related factors. Despite of those limitations, this study is the first of its kind, up to our knowledge, investigated depression among healthcare workers in Tabuk, Saudi Arabia using a validated tool. In conclusion, depression is a relatively common health problem affecting healthcare workers in NorthWest Armed forces hospital, Tabuk. However, in majority of cares, the depression was of mild degree. 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Occupational stress and depression among hospital physicians in Taiwan Depression-Burnout overlap in physicians Stress, depression and burnout among hospital physicians in All authors contributed evenly in the conceptualization, drafting, data analysis, writing and proofreading of the research. 1. Name of the registry: researchregistry 2. Unique Identifying number or registration ID: researchregistry6940 3. Hyperlink to your specific registration (must be publicly accessible and will be checked): https://www.researchregistry.com/registe r-now#user-researchregistry/registerresearchdetails/60df014e3b0 b3e002545a2d4/ Guarantor Salha Ali Almarhapi. The authors declare no conflict of interest.