key: cord-0819896-i41jtaxq authors: Ogura, Yasuaki; Morimoto, Hiroki; Otsuka, Masaki; Tokura, Yoshiki title: Development of IgA vasculitis after SARS‐CoV‐2 vaccination date: 2022-04-20 journal: Journal of Cutaneous Immunology and Allergy DOI: 10.1002/cia2.12242 sha: 2e98ce272dab40a5e72f8668f2421268e968ca05 doc_id: 819896 cord_uid: i41jtaxq We report a case of IgA vasculitis that occurred 1 week after COVID‐19 vaccination. Like influenza vaccine, SARS‐CoV‐2 vaccine is considered to have a potential to produce immune complexes with IgA. Given that patients with a history of IgA vasculitis may be flared up following SARS‐CoV‐2 vaccination, individuals with a history of IgA vasculitis should be carefully followed up after receiving the vaccine. [Image: see text] IgA vasculitis is a small vessel vasculitis with deposits of IgA immune complex. It usually manifests small palpable purpura on the lower legs, but severer cases may be accompanied by joint and abdominal pain. Moreover, deposition of IgA immune complexes in the small vessels of the kidney induces IgA nephropathy with hematuria. While streptococcal, mycoplasma, and viral infections are the main causes, various vaccines are also causative. 1 Here, we report a case of IgA vasculitis that occurred 1 week after COVID-19 vaccination. Henoch-Schönlein purpura following influenza vaccinations during the pandemic of influenza A (H1N1) Reactivation of IgA vasculitis after COVID-19 vaccination Reactivation of IgA vasculitis following COVID-19 vaccination Possible HSP reactivation post-COVID-19 vaccination and booster Post-COVID-19 vaccination IgA vasculitis in an adult Henoch-Schönlein purpura presenting post COVID-19 vaccination IgA vasculitis in adult patient following vaccination by ChadOx1 nCoV-19 Case of immunoglobulin A vasculitis following coronavirus disease 2019 vaccination Henoch-Schönlein purpura following the first dose of COVID-19 viral vector vaccine: a case report New insights in the pathogenesis of immunoglobulin A vasculitis (Henoch-Schönlein purpura)