key: cord-0840710-zmpcsruw authors: Al-lami, Rasha A. title: COVID-19 infection just before or during early pregnancy and the possible risk of placenta accreta spectrum (PAS) or preeclampsia, a letter to the editor. date: 2021-06-16 journal: Am J Obstet Gynecol DOI: 10.1016/j.ajog.2021.06.059 sha: 4badf8b62182358ca814439ea8b477f8a95a0843 doc_id: 840710 cord_uid: zmpcsruw nan I read with great interest the findings presented by Patberg and colleagues. 1 Their 17 findings of higher rate of villitis of unknown etiology and fetal vascular disruption in the 18 placental tissues taken from term deliveries of pregnant women with COVID-19 make it 19 reasonable to assume pathological changes in the fetal-maternal interface and endometrium, and 20 their potential implication in decidualization, placentation, and trophoblast invasion if pregnant 21 women had COVID-19 just before pregnancy or during first trimester. Whether these 22 Coronavirus disease 2019 infection and placental 64 histopathology in women delivering at term The SARS-CoV-2 receptor, angiotensin-67 conver6ng enzyme 2, is required for human endometrial stromal cell decidualiza6on †. Biol 68 Reprod Complex regulation of decidualization: a 70 role for cytokines and proteases--a review Decidual Control of Trophoblast Invasion Placenta accreta spectrum: pathophysiology 75 and evidence-based anatomy for prenatal ultrasound imaging