key: cord-0860136-ixx4aiwk
authors: Yamamoto, Koichiro; Oka, Kosuke; Sakae, Hiroyuki; Otsuka, Fumio
title: Acute Pancreatitis Related to COVID-19 Infection
date: 2021-05-14
journal: Intern Med
DOI: 10.2169/internalmedicine.7400-21
sha: ea5627352507b1b6405954c9b1c779cbd97f9605
doc_id: 860136
cord_uid: ixx4aiwk

nan

A 70-year-old woman presented with coronavirus disease 2019 (COVID-19). Her symptoms included cough, which had persisted for 5 days and sore throat. She was obese (body mass index, 29.5 kg/m 2 ) and had diabetes mellitus, dyslipidemia, hypertension, and a history of cholecystectomy. Remdesivir and dexamethasone (6 mg) improved her symptoms. On the 14th day after the development of COVID-19, her serum levels of pancreatic enzymes were elevated (Picture, upper). Simultaneously, abdominal tenderness appeared and computed tomography showed an enlarged pancreatic parenchyma (Picture, lower). She was diagnosed with acute pancreatitis, which was ameliorated by fasting and fluid therapy.

COVID-19 is rarely complicated by acute pancreatitis (1). In such cases, angiotensin-converting enzyme 2 receptors in pancreatic cells may be associated with the pathogenesis (2) . Considering that pancreatitis occurred after the administration of dexamethasone and remdesivir, these drugs might have been involved in the pancreatitis of our case. This case suggested that acute pancreatitis could develop immediately after treatment for COVID-19.

COVID-19 presenting as acute pancreatitis

Coronavirus disease-19 (COVID-19) associated with severe acute pancreatitis: case report on three family members

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