key: cord-0861310-lms3sj2n
authors: Aslan, Serdar
title: Multiple Reversed Halo Sign on Chest CT in COVID-19 Pneumonia
date: 2020-11-09
journal: Arch Bronconeumol
DOI: 10.1016/j.arbres.2020.10.018
sha: 3f1f370e374b1db3de62e66105d92481614269a9
doc_id: 861310
cord_uid: lms3sj2n

nan

A 43-year-old female presented to the pandemic outpatient clinic of our hospital with the complaints of cough, diarrhea and loss of taste for 3 days. She is a healthcare worker and that her colleagues with whom she worked have been diagnosed with COVID-19. Vital signs and physical examination were normal. Laboratory tests revealed an increased D-Dimer level (1365 ng/ml). Chest CT and 3D volume-rendering images demonstrated bilateral, multilobar peripherally placed lesions with a "multiple reversed halo sign" (Fig. 1A and B) . A nasopharyngeal swab was positive for COVID-19. The patient was hospitalized and treated with hydroxychloroquine and enoxaparin. On day 7 of hospitalization, clinical symptoms improved and patient was discharged.

The reversed halo sign is defined as an area with ground-glass opacity surrounded by partial or complete rings of consolidation. 1 E-mail address: serdaraslan28@hotmail.com This sign is nonspecific and has been reported in cryptogenic, noncryptogenic organizing pneumonia, viral and fungal pneumonia, neoplastic processes and many of other pathologies. 2 This sign is often associated with severe cases and occurs long after symptom onset. Such findings in these cases suggest that non-neoplastic processes such as organized pneumonia are one of the mechanisms of lung fibrosis. 2 

Chest CT manifestations of new coronavirus disease 2019 (COVID-19): a pictorial review

Longitudinal CT findings in COVID-19 pneumonia: case presenting organizing pneumonia pattern