key: cord-0870790-b8cbx8xh
authors: Lazzeri, Chiara; Ghinolfi, Davide; Marzi, Vincenzo Li; Serni, Sergio; De Simone, Paolo; Franchi, Federico; Luzzi, Luca; Scolletta, Sabino; Peris, Adriano
title: OUT-OF-HOSPITAL CARDIAC ARREST AND DONATION AFTER CIRCULATORY DEATH DURING THE COVID-19 PANDEMIA
date: 2020-07-06
journal: Resuscitation
DOI: 10.1016/j.resuscitation.2020.06.028
sha: 430b27d7ece57a5e5473334553edf98089ff8166
doc_id: 870790
cord_uid: b8cbx8xh

nan

The rapid emergence of the novel coronavirus (COVID) disease posed potential obstacle for organ procurement and transplantation worldwide and in European countries [1] .

In Italy the outbreak was rapid and as of March 22, 2020, and [3] ince March 10, the Italian government extended restrictions (comprising quarantine and self-isolation measures) from

Northen areas to the whole country. Simoultaneosly the Italian National Institute of Health and the National Transplant Centre (CNT) defined regulatory measures for organ transplantation to maintain transplantation activity, from both deceased and living-related donors [3] . Among these measured, a systematic COVID-19 surveillance was imposed for deceased and living donors and only negative COVID donors were considered for transplantation [3] .

In this setting, uncontrolled donation after circulatory death (which has been recognized as an added-on activity ) appears extremely challenging, due to logistic, organizational issues so that The uDCD program was implemented at Careggi, teaching hospital since June 2016 [3] , at Le Scotte Teaching Hospital (Siena) since 2018 and it proved an effectiveness comparable to other European countries [4, 5) .

We described the uDCD activity at Careggi Teaching and at Le Scotte Teaching Hospital during the COVID outbreak, from March 1 st to May 23 2020

In Florence four patients (40%) were identified as potential uDCDs (COVID negative in all). Kidneys were recovered from two uDCDs. Two kidneys were not suitable for transplantation due to high resistance during machine perfusion, while two kidneys were successfully transplanted. Two livers were recovered and one transplanted, since macrosteatosis > 50% was detected in the other one.

In Siena, onr patient was not enrolled due to longer times.

In Tuscany, the uDCD program proved to be feasible during the COVID pandemia in centers 

Hoeck RA et al Immediate impact of COVID-19 on transplant activity in the Netherlands

Information for transplant programs regarding novel Coronavirus

Out of hospital cardiac arrest and uncontrolled donation after circulatory death in a tertiary cardiac arrest center

Utilization rate of uncontrolled donors after circulatory death a three year single center investigation

Donation after circulatory death today: an updated overview of the European landscape