key: cord-0891096-um9p8w6y authors: Mathew, Thomas; John, Saji K.; Kumar G. G., Sharath title: Acute SARS‐CoV‐2 infection and reversible splenial hyperintensity: A stroke mimic date: 2021-09-27 journal: J Am Coll Emerg Physicians Open DOI: 10.1002/emp2.12562 sha: e54ee8a7982663ea3044a6fcc88b59b7b2c4f63c doc_id: 891096 cord_uid: um9p8w6y nan MR venogram was normal. The patient was given aspirin 75 mg and was managed as COVID-19 associated stroke. He was referred to neurology outpatient for a second opinion. MRI brain findings were reviewed and were suggestive of transient splenial sign or dot sign ( Figure 1) . A repeat MRI of the brain showed complete resolution of the lesion and his aspirin was stopped ( Figure 2 ). Transient splenial sign (TSS) or "dot sign" is a non-specific sign that Boomerang sign: clinical significance of transient lesion in splenium of corpus callosum Cytotoxic lesions of the corpus callosum that show restricted diffusion: mechanisms, causes, and manifestations COVID-19-associated mild encephalitis/encephalopathy with a reversible splenial lesion Cytotoxic lesion of the corpus callosum as presenting neuroradiological manifestation of COVID-2019 infection Acute SARS-CoV-2 infection and reversible splenial hyperintensity: A stroke mimic