key: cord-0911897-opvazihg authors: Houhou‐Fidouh, Nadhira; Bucau, Margot; Bertine, Mélanie; Minh, Thu Nguyen Thi; Picone, Olivier; Salakos, Eleonora; Luton, Dominique title: Preliminary results on transmission of SARS‐CoV‐2 antibodies to the fetus and serum neutralizing activity date: 2022-04-06 journal: Int J Gynaecol Obstet DOI: 10.1002/ijgo.14185 sha: 3f46faaa763b717cb828c6287160fbd9cfaaf5a0 doc_id: 911897 cord_uid: opvazihg During pregnancy early third trimester immunization against SARS‐CoV‐2 confers optimal immunity to the neonate. Reports about SARS-CoV-2 maternal-fetal transmission 1 exist including data on the transmission of maternal antibodies to the fetus. But there are few data concerning the neutralizing activity of the transmitted antibodies. Among 12 delivered patients with diagnosis confirmed by nasopharyngeal RT-PCR, all other samples at delivery were negatives. All the neonates from IgG-positive mothers were also IgG positive, with no IgM. Main findings were that neonates with positive neutralization activity on cord blood had a longer delay be- No. Research data are not shared. Synthesis and systematic review of reported neonatal SARS-CoV-2 infections Maternal antibody response, neutralizing potency, and placental antibody transfer after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection Perinatal transmission of SARS-CoV-2 and transfer of maternal IgG/neutralizing anti-SARS-CoV-2 antibodies from mothers with asymptomatic infection during pregnancy Timing of SARS-CoV-2 vaccination during the third trimester of pregnancy and transplacental antibody transfer: a prospective cohort study How to cite this article: Houhou-Fidouh N, Bucau M Preliminary results on transmission of SARS-CoV-2 antibodies to the fetus and serum neutralizing activity