key: cord-0916020-9ggdhd8v authors: Dong, Huanhuan; Feng, Lufang; Zhang, Na; Zhu, Zeshan; Liu, Xingrong title: COVID-19 in Gansu Province, China: Characteristics, measures, and effects date: 2021-01-13 journal: Journal of global health DOI: 10.7189/jogh.11.03001 sha: ef6220a305d47a05d03977b2ae8a64996cbdf28f doc_id: 916020 cord_uid: 9ggdhd8v nan C orona Virus Disease-2019 (COVID-19) infections have spread worldwide since it was first reported in December 2019 and is now a global pandemic. So far, China has been successful in preventing and controlling the spread of the disease. Although economically underdeveloped, the Gansu province of China also responded quickly and achieved excellent results in preventing and controlling the epidemic, with high recoveries and low mortality rates. This paper aims to discuss the measures adopted by the Gansu Province of China for COVID-19 prevention, treatment, and control and to provide reference for preventing, treating, and controlling the disease. The epidemic was first reported in Gansu Province on January 23, 2020, and by March 14, 2020, all the 91 local confirmed cases had been concluded [2] . No case was reported in Wuwei, Jiuquan, and Jiayuguan, whereas Lanzhou and Tianshui reported more than 10 cases. As of November 3, 2020, 88 imported cases had been reported in Gansu province, of which 78 were cured, and 10 were treated in isolation in provincial designated hospitals [3] . COVID-19 in Gansu Province, China: Characteristics, measures, and effects Most confirmed cases were young adults, and this may be related to the economic activities of the population. Most young adults are either students or employed, and therefore exhibit high mobility. The youngest patient was one year old, whereas the oldest was 94 years, indicating that the novel coronavirus affected people of all ages. Notably, the two patients who died from the condition were older, immunocompromised, and exhibited poor physical state [4] . For the elderly in poor physical state, the disease quickly progressed to severe cases, which challenged treatment and rehabilitation. Most cases were reported in Lanzhou and Tianshui cities, which could be related to their large number of permanent residents and migrant populations. As such, controlling the disease in the two cities was more challenging. Most of the new cases had been in physical contact with the confirmed cases [5] , suggesting that human-to-human transmission was common. Besides, most of the cases were linked to the epidemic in Wuhan [6] . The cases of COVID-19 reported in Gansu province were initially from people who had traveled from other provinces, but later most cases were from the local human-to-human transmission, particularly within or between households [5] . Thus, family interactions were the main sites where COVID-19 was transmitted, and close contact between family members was the primary mode of transmission. Given that the virus is highly transmissible from person to person [7] , it was necessary to strengthen the protection consciousness of family members and beware of the occurrence of household cluster epidemics. A typical case is a cluster epidemic caused by a confirmed case sharing a meal with relatives in Tianshui (Figure 1) . Most confirmed COVID-19 cases had fever and cough, which were sometimes accompanied by fatigue, expectoration, headache, chest stuffiness, etc. Some patients only exhibited a cough without fever. Therefore, close contact was strictly avoided to cut off the transmission from asymptomatic patients [8] . Gansu province responded quickly following the COVID-19 outbreak. Among the measures taken were early detection and timely isolation and treatment of the patients. Thus, all local cases were cleared in less than two months. Also, the Traditional Chinese medicine plays an important role in preventing and treating COVID-19. cases from abroad were successively treated within a short time. Gansu province started the first level response of major public health emergencies on January 25, which involved implementing containment measures to curb outbreaks, such as closing schools, cinemas, markets, and other public places. Social gatherings, like holding banquets, parties, and other entertainment, were also stopped. Timely isolation, diagnosis, and treatment of the confirmed cases and their contacts were strictly followed [9] . In total, 91 local cases were confirmed in Gansu province, of which 89 (97.8%) were cured, and 2 (2.2%) died [5] , indicating a high survival rate. As of November 3, 2020, no new local case had been reported. It is noteworthy that no case involving a medical staff was reported in Gansu Province, indicating that the first level response of major public health emergencies was efficient. Moreover, traditional Chinese medicine was employed to treat the condition. Gansu health providers insisted on using a combination of traditional Chinese and Western medicine for the prevention, treatment, and rehabilitation of COVID-19 patients. This leveraged the advantages of traditional Chinese medicine, thereby reducing the mortality rate. As of March 2, 89 (97.8%) cases had been successfully treated using traditional Chinese medicine. Notably, Gansu province ranks high in the use of traditional Chinese medicine for treating COVID-19. The treatment approach has been remarkably effective in treating the disease [10] . In conclusion, the critical measures for preventing and controlling COVID-19 are early detection, timely isolation and treatment of the initial cases, timely contact tracing, and centralized isolation and observation. At present, cases of COVID-19 infections have reduced significantly, however, the disease remains. Besides, with the resumption of daily economic activities, the risk of disease transmission has increased. Therefore, individuals and organizations should still take the necessary precautions to avoid another wave of infections. Epidemic prevention and control is a protracted war and requires concerted efforts of the whole country. 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Dynamic of control of the Novel Coronavirus Pneumonia We thank all the Gansu public health staff who did the epidemiological investigation of the COV-ID-19 and the medical staff for their efforts in the treatment of patients. The views expressed in the submitted article are our own and not an official position of the institution. And the research has been approved by the academic committee. Authorship contributions: All authors contributed to the conceptualization, writing, and revisions of the paper. The authors completed the ICMJE Unified Competing Interest form (available upon request from the corresponding author), and declare no conflicts of interest.