key: cord-0952635-96yhmjdk
authors: Alay, Handan; Bilen, Handan
title: Aquagenic syringeal acrokeratoderma in an adolescent female with COVID-19
date: 2021-04-12
journal: Revista da Sociedade Brasileira de Medicina Tropical
DOI: 10.1590/0037-8682-0152-2021
sha: 49a15c55f82eb11ccbff0d38d1082b2d1f92d95b
doc_id: 952635
cord_uid: 96yhmjdk

nan

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Handan Alay [1] and Handan Bilen [2] [1]. Ataturk University, Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Erzurum, Turkey. [2] . Ataturk University, Faculty of Medicine, Department of Dermatology, Erzurum, Turkey. A 14-year-old female patient reported stinging and pain following contact with water and presented with raised white eruptions 10 days after being diagnosed with COVID-19. The patient reported that the eruptions appeared within 5 min after bathing and disappeared in 2-3 h. She had no history of plantar involvement, skin diseases, atopy, drug use, compression or trauma. Dermatological examination revealed that the following changes occurred upon contact with water: hypopigmentation in both palmar regions, thickening of the skin, and the appearance of pronounced palmar creases and symmetrical, white-shiny papules (diameter, 1 mm) (Figure 1A) . Physical examination and laboratory test findings were unremarkable. Suspecting that the lesions may have been caused by frequent handwashing during the COVID-19 pandemic, the patient was advised to avoid using disinfectants unless absolutely necessary and to use soap and water for washing. Two months after following this advice, the lesions appeared to have regressed (Figure 1B) , and by the third month, the lesions did not appear upon contact with water (Figure 2) .

Aquagenic syringeal acrokeratoderma

Aquagenic syringeal acrokeratoderma

Aquagenic Syringeal Acrokeratoderma from Extensive Water Immersion during the COV-ID-19 Pandemic Outbreak

Aquagenic syringeal acrokeratoderma (ASA) is a rare entity generally affecting the palms of the hands and soles of the feet. ASA may be associated with cystic fibrosis, asthma, allergic rhinitis, a COX-2 inhibitor, and spironolactone use 1,2 . ASA has been reported following frequent exposure to water during the COVID-19 pandemic 3 .Although rare, the possibility ASA development following excessive exposure to disinfectants that adversely affect the skin barrier should not be forgotten during this pandemic.

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