key: cord-0956527-ddflsi3o
authors: Mungmunpuntipantip, Rujittika; Wiwanitkit, Viroj
title: Mortality-related immune features and COVID-19
date: 2021-02-04
journal: J Allergy Clin Immunol Pract
DOI: 10.1016/j.jaip.2020.11.062
sha: 7008cbf7679c37caf123b3b223ec580262d98e7b
doc_id: 956527
cord_uid: ddflsi3o

nan

up with current regulations to maintain compliance in light of the changes during the COVID-19 pandemic and beyond also requires considerable effort. 2 What is uniquely addressed in this letter are the practical issues that allergists and immunologists face with telemedicine. Although spirometry is limited at this time, technologies are being created and implemented to accomplish home forced expiratory volume in 1 second measurement. 3 Assessing and teaching the inhaler and emergency epinephrine device technique can be performed remotely and re-evaluated at follow-up visits via telemedicine. Telemedicine has also been valuable to evaluate and monitor our most at-risk patients, such as those with immunodeficiency, as they may be fearful of returning to the clinic for routine in-person evaluations. Time will reveal more data in our field as we are able to obtain cost-benefit analysis for allergy and immunology telemedicine encounters. By providing innovative, valuable, and cost-effective care while educating our fellows and continuing to rapidly adapt in times of need, we will persist in pushing open the door of modern medical technology in health care. 

To the Editor:

We would like to share ideas on the report ''Predictive nomogram for severe COVID-19 and identification of mortality-related immune features.'' 1 Cai et al 1 noted that ''the abundance of CD45RO 1 CD3 1 T cells and neutrophil-to-lymphocyte and neutrophil-to-natural killer cell ratios may serve as useful prognostic predictors in severe patients.'' The finding from this small study is interesting. Indeed, the change in white blood cells in coronavirus disease 2019 (COVID-19) is possible and might contribute to the clinical manifestations. 2 Several factors can additionally contribute to the severity of infection. The underlying disease of the patient might also be reactivated because of COVID-19. Nevertheless, as noted by Lupia et al, 3 there is a role of cytokine response during COVID-19 illness that is an important determinant for severity, and the clinical problem due to change in white cells might be overt during the recovery stage of COVID-19 when there is a decreased level of cytokine response. 

The forced renaissance of telemedicine during COVID-19: a fellow-in-training's perspective

Work Group Report: COVID-19: unmasking telemedicine

Home self-monitoring in patients with asthma using a mobile spirometry system

Predictive nomogram for severe COVID-19 and identification of mortality-related immune features

Differential white blood cell count in the COVID-19: a cross-sectional study of 148 patients

Giardiasis reactivation during severe SARS-CoV-2 infection

Reply to ''Mortality-related immune features and COVID-19

We have read with interest the comments by Mungmunpuntipantip and Wiwanitkit, 1 and we agree that cytokines are associated with disease severity and have an effect on the underlying J ALLERGY CLIN IMMUNOL PRACT FEBRUARY 2021