key: cord-0984945-lr4u4elr authors: Brazão, Cláudia; Alpalhão, Miguel; Aguado-Lobo, Marta; Antunes, Joana; Soares-de-Almeida, Luís; Filipe, Paulo title: Is there a link between Guttate psoriasis and SARS-CoV-2? A series of three cases() date: 2021-12-30 journal: An Bras Dermatol DOI: 10.1016/j.abd.2021.07.006 sha: d6ae2a6cb5c9610d86d9865a0f268e179fafc9f8 doc_id: 984945 cord_uid: lr4u4elr nan activation. [1, 2] Viral upper respiratory infections may also be implicated, typically occurring two to three weeks before the onset of guttate lesions. [1, 3] We report three cases of GP following Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection and BNT162b2 mRNA vaccine. A 42-year-old Caucasian male with a history of chronic plaque psoriasis developed multiple erythematous scaly papules and plaques on the face, trunk, upper and lower limbs, and scaly erythematous plaques over the elbows and knees (Fig. 1 Study conception and planning. None declared. Diagnosis and Management of Cutaneous Psoriasis: A Review The association of sore throat and psoriasis might be explained by histologically distinctive tonsils and increased expression of skin-homing molecules by tonsil T cells Respiratory virus infection triggers acute psoriasis flares across different clinical subtypes and genetic backgrounds Superantigenic character of an insert unique to SARS-CoV-2 spike supported by skewed TCR repertoire in patients with hyperinflammation BNT162b2 mRNA COVID-19 vaccine: first approval