key: cord-0989466-ji0bjbfv authors: Epelboin, Loïc; Blondé, Renaud; Nacher, Mathieu; Combe, Patrice; Collet, Louis title: COVID-19 and dengue co-infection in a returning traveller date: 2020-07-13 journal: J Travel Med DOI: 10.1093/jtm/taaa114 sha: 52adcc8bb78ae8b4b0066f73445a9d10cd77810d doc_id: 989466 cord_uid: ji0bjbfv In march 2020, a pandemic of respiratory infection due to the SARS-CoV2 is underway, dengue fever epidemics are at the same time present in many regions of the inter-equatorial zone. We report the first cases of covid19-dengue co-infection, which occurred in Mayotte, a French island in the Indian Ocean. U N C O R R E C T E D M A N U S C R I P T 2 In march 2020, a pandemic of respiratory infection due to the SARS-CoV2 is underway, dengue fever epidemics are at the same time present in many regions of the inter-equatorial zone. We report the first cases of covid19-dengue co-infection, which occurred in Mayotte, a French island in the Indian Ocean. reported, mostly DENV1 serotypes. It is therefore likely that the patient acquired dengue upon returning from France, as the incubation time for COVID-19 is 3 to 5 days in general, but can be up to 14 days, as it is 2 to 7 days for dengue fever, being up to 14 days as well. To our knowledge, COVID19 and dengue virus co-infection has not been reported yet, In the present case, it was not the biological assessment which challenged the clinicians, but the occurrence of a diffuse exanthema, which prompted the search for dengue fever. In Thailand, at the beginning of the epidemics, a case was reported describing a COVID-19 patient who initially presented with a skin rash, which was initially considered as a dengue infection, before the diagnosis was corrected. 5 In Lombardy, Italy, erythematous rash was the most common lesion among 88 patients with proved COVID-19 infection. Thus, COVID-19 may present with cutaneous manifestations, which could be confused with dengue fever. To conclude, COVID1-19 and dengue virus epidemics occur at the same time in tropical areas and lead to 2 major challenges: the misdiagnosis of two infections with similar presentation and the risk of greater severity. Severe dengue in travellers: Pathogenesis, risk and clinical management Sars-cov-2 and legionella co-infection in a person returning from a nile cruise Covert covid-19 and false-positive dengue serology in singapore Covid-19 and dengue, co-epidemics in ecuador and other countries in latin america: Pushing strained health care systems over the edge Covid-19 can present with a rash and be mistaken for dengue Funding statement : none