key: cord-0999352-e7unja98 authors: Granell, M.; Sanchís, N.; López-Cantero, M.; Romero, C. S.; Garutti, I.; Vicente, R. title: Analysis and review of the perioperative management of COVID-19 patients in thoracic surgery date: 2021-06-09 journal: Rev Esp Anestesiol Reanim (Engl Ed) DOI: 10.1016/j.redare.2020.08.010 sha: b7b3f756f9992b28c425e2d14e4512bd9e579ba1 doc_id: 999352 cord_uid: e7unja98 nan Letter to the Editor Analysis and review of the perioperative management of COVID-19 patients in thoracic surgery Análisis y revisión del manejo perioperatorio del paciente covid-19 en la cirugía torácica. Autores: Dr. Granell M. 1,2,3 , Nerea Sanchís N. 1 , Dra. López-Cantero M. 4 Debido a la grave situación de pandemia que vivimos causada por el COVID-19, la Sección de Anestesia Cardiaca, Vascular y Torácica de la SEDAR pretende dar información de los aspectos más relevantes a considerar en pacientes con sospecha o infección confirmada por coronavirus que van a ser sometidos a cirugía torácica. Creemos que es esencial mantener una óptima transmisión de información para llevar a cabo maniobras seguras, tanto para los pacientes como para el personal sanitario. La estrategia de manejo debe basarse en una organización exquisita del trabajo, definiendo quién, cómo y cuándo va a realizar cada tarea y procedimiento. Las recomendaciones que se proponen, tras valorar el riesgo-beneficio en el escenario específico de la cirugía de tórax y la experiencia de expertos en torácica obtenida en el estudio COV2-VIAEREA, tratan de asesorar sobre los aspectos anestésicos claves a tener en cuenta ante una eventual necesidad de cirugía torácica en el contexto de la pandemia por COVID-19. Palabras clave: COVID-19; cirugía torácica; manejo de vía aérea; aislamiento/separación pulmonar; ventilation unipulmonar. Due to the serious pandemic situation that we live caused by COVID-19, the Cardiac, Vascular and Thoracic Anesthesia Section of SEDAR aims to provide information on the most relevant aspects to consider in patients with suspected infection or infection confirmed by coronavirus that they will undergo thoracic surgery. We believe that it is essential to maintain an optimal transmission of information to carry out safe maneuvers, both for patients and healthcare personnel. The management strategy must be based on an exquisite organization of work, defining who, how and when will perform each task and procedure. The proposed recommendations, after assessing the risk-benefit in the specific scenario of thoracic surgery and the experience of thoracic experts obtained in the COV2-VIAEREA study, try to advise on the key anesthetic aspects to take into account on the eventual need for thoracic surgery in the context of this COVI-19 pandemic. Key words: COVID-19; thoracic surgery; airway management; lung isolation/separation; one-lung ventilation. To the Editor: Anaesthetic and surgical procedures in COVID-19 patients that require orotracheal intubation, extubation, secretion drainage and non-invasive mechanical ventilation are considered high risk for viral transmission. This is particularly true of anaesthesia and thoracic surgery, due to the need for frequent airway manipulation and exposure of the airway in the surgical field. This has prompted the Cardiac, Vascular and Thoracic Anaesthesia Division to review the recommendations endorsed by different international societies and the latest publications on this subject in order to advise anaesthesiologists on key aspects of thoracic surgery. The overall rules for general anaesthesia in COVID-19 patients and patient transfers between hospital units do not differ from the general recommendations put forward by the SEDAR and other guidelines already published in specialty journals 1 . The following recommendations are specifically related to thoracic surgery techniques 2-4 : 1) elective intubation is always preferable to emergency intubation; 2) High Efficiency Particulate Air (HEPA) antibacterial filters must always be used in the breathing circuit (inspiratory and expiratory limb and y-piece), in the lumen of the bronchial blocker (BB) or double lumen tube (DLT) placed in the surgical lung (or at both ends of the DLT if a sequential collapse is planned), when CPAP is used (limb corresponding to the collapsed lung) and/or between the chest drain and the reservoir; 3) if the patient is already intubated, prioritise BBs; 4) minimize exposure during BB or DLT insertion and/or repositioning; 5) always use closed circuit systems; 6) avoid respirator disconnections and make sure the valves are tightly sealed (prolong apnoea and clamp the endotracheal tube) when performing bronchoscopy or aspirating secretions; 7) plan for hypoxaemia management during one-lung ventilation; 8) perform a detailed evaluation of patients with moderate or severe ARDS secondary to COVID-19 based on the urgency of the surgical indication. Intubation must be safe for the surgical team and appropriate for the patient. Avoid suboptimal, repeated attempts and innovative techniques (SAR = Safe, Adequate, Rapid). Ideally, anaesthesia should be induced in a negative pressure operating room. If this is not possible, increase and escalate safety measures. Pre-oxygenation with 100% FiO2 for at least 5 minutes is mandatory to avoid or at least reduce the need for manual ventilation during induction, which is performed by 2 anaesthesiologists. Premedicate with lidocaine or opioids to minimize the cough reflex, then perform rapid sequence induction for hypnosis and rapid neuromuscular relaxation (rocuronium 1.2 mg/kg). After inserting the endotracheal tube (ETT) or TDL using a video laryngoscope, the device of choice 1 , the cuff must be inflated immediately, and always before starting mechanical ventilation. As many as 40% of SEDAR members participated in the CoV-2-VIAEREA study approved by the Institutional Review Board of the Valencia General University Hospital Consortium (April 24, 2020) and sponsored by SEDAR. Of these,14.4% had considerable experience in thoracic surgery, and rated their choice of video laryngoscope for DLT insertion as follows (6 top Several guidelines on difficult airway (DA) management have been published 5 , but recommendations differ when treating COVID-19 patients 1 ; awake intubation in a patient meeting DA criteria should be avoided and reserved solely for non-deferrable or emergency surgery. Administer mild intravenous sedation and avoid topical analgesics. If 3 attempts at intubation are unsuccessful in a patient with unanticipated DA, secure the airway with a 3rd generation supraglottic device and then perform intubation with a fibreoptic bronchoscope (FOB). Regarding lung isolation and/or separation in COVID-19 patients: when only lung separation is required to optimize exposure during surgery, either DLTs or BBs can be used; when lung isolation is indicated 5 , use a DLT. In exceptional cases, intubate with an ETT and then exchange for a DLT. The most obvious recommendations for lung isolation with a BB is in patients that are already intubated or that meet the criteria for DA, patients undergoing short surgical procedures, and in patients that will most likely require postoperative mechanical ventilation 5 . In the CoV-2-VIAEREA study, the BBs of choice for COVID-19 patients were, in descending order: Uniblocker (33.3%), Arndt (23.9%), Univent (18.1%), EZ Blocker (12.9%), Cohen (9.7%), and Coopdech (2.6%). To verify correct placement of the DLT or BB, choose a single-use rather than reusable flexible bronchoscope, or a DLT or ETT with a built-in camera (Viva Sight DL or Viva Sight SL, respectively) 2 . DLTs are usually placed with the aid of FOB; however, the use of DLTs with a built-in camera has been gaining ground because they have several advantages over conventional DLTs: optimal insertion without the need for FOB in 99% of cases, shorter intubation time, and the possibility of correcting malpositioning without FOB, although FOB may be needed in 5%-15% of cases. In the CoV-2-VIAEREA study, anaesthesiologists rated pulmonary separation devices in COVID-19 patients as follows, in descending order (6 top choice, 1 last choice): Conventional DLT (4.7), DLT with built-in camera (3.9), BB through ETT with built-in camera (3.3), FOB-guided BB through ETT (3.2), UNIVENT tube and FOB (2.8) and FOB-guided endobronchial ETT (2.4). General recommendations for the management of one-lung ventilation (ONL) in COVID-19 patients are the same as for lung protection, although patients are more prone to haemodynamic instability. It may be necessary to apply CPAP to the nondependent lung, or extracorporeal membrane oxygenation (ECMO) might be required. There is no evidence to recommend performing thoracic surgery without intubation in patients with highly contagious diseases, so the use of non-invasive ventilation (NIV) and high flow nasal cannulas (HFNC) is not recommended during thoracic surgery 2 . The timing of extubation must be decided on a case-by-case basis (Fig. 1) , choosing the option that is safest for both the patient and healthcare workers. If the anaesthesiologist decides to extubate in the operating room due to the unlikelihood of postoperative mechanical ventilation and the patient's stable status, the general guidelines for patients with suspected coronavirus should be followed 1 . In patients with DA, the recommendations provided by other authors should be followed 5 . When postoperative ventilation is required, proceed as follows: 1) remove any independent BBs or those attached to the Univent; 2) DLTs should be exchanged for an ETT with subglottic secretion drainage (high-risk manoeuvre); 3) if a DLT was used, but very brief postoperative ventilation is expected, the distal end of the DLT can be withdrawn as far as the trachea. Finally, in the CoV-2-VIAEREA study, anaesthesiologists rated extubation techniques as follows, in descending order: extubation in the operating room (89.5%), removal of the BB and transfer with an ETT (4.9%), exchange DLT for ETT and transfer to the ICU (4.9%), or withdraw the tip of the DLT to the trachea and transfer to the ICU (0.6%). The authors have not received any funding. Figure 1 Extubation in a COVID-19 patient undergoing thoracic surgery. gr1 Fig. 1 . Extubación en paciente COVID-19 sometido a cirugía torácica. Consensus guidelines for managing the airway in patients with COVID-19: Guidelines from the Difficult Airway Society, the Association of Anaesthetists the Intensive Care Society, the Faculty of Intensive Care Medicine and the Royal College of Anaesthetists Thoracic Anesthesia of Patients with Suspected or Confirmed 2019 Novel Coronavirus Infection: Preliminary Recommendations for Airway Management by the EACTA Thoracic Subspecialty Committee Recomendaciones de consenso SEPAR Y AEER sobre el uso de la broncoscopia y la toma de muestras de la vía respiratoria en pacientes con sospecha o con infección confirmada por Covid-19 Recomendaciones para el manejo anestésico del paciente covid19 sometido a cirugía torácica Review of difficult airway management in thoracic surgery The authors have no conflict of interest to declare.