key: cord-1000396-meebb4ic authors: Guan, Lili; Zhou, Luqian; Zhang, Jinnong; Peng, Wei; Chen, Rongchang title: More awareness is needed for severe acute respiratory syndrome coronavirus 2019 transmission through exhaled air during non-invasive respiratory support: experience from China date: 2020-03-19 journal: Eur Respir J DOI: 10.1183/13993003.00352-2020 sha: dc3717164035118202545e92237895cb7f74f18c doc_id: 1000396 cord_uid: meebb4ic Non-invasive respiratory support plays an essential role in the treatment of COVID-19. More awareness is needed of viral transmission through exhaled air. http://bit.ly/39kNrrF When oxygen is delivered through nasal catheter, mask or non-invasive ventilation (NIV), substantial exhaled air is released into the air, which can increase dispersion of the virus, and subsequently increase the risk of nosocomial infection [4] . Prior studies have suggested that the application of high-flow nasal cannula (HFNC), NIV through the specific mask with optimised vent holes or the helmet with a double-limb circuit may lower the risk of airborne transmission [5, 6] . Performing non-invasive respiratory support in a single, well-ventilated, negative pressure ward is also considered a safe option. Currently, however, the majority of patients are still receiving respiratory support through nasal catheter or common mask in general wards or emergency departments with limited medical resources. The potential for airborne transmission in this population has not received enough attention. Furthermore, a significant proportion of suspected patients with mild to no symptoms who are managing at home may also require long-term home oxygen or NIV treatment (e.g. patients with advanced staged COPD). These patients may increase the risk of family cluster infections by the widespread dispersion of exhaled air in their homes. Non-invasive respiratory support plays an essential role in the treatment of COVID-19, and more awareness is needed regarding the increased risk of viral transmission from exhaled air. Medical staff should utilise personal protective equipment when providing respiratory support therapy. Patients should wear a medical mask when receiving conventional oxygen therapy or HFNC in order to reduce air dispersion. When performing NIV therapy, because helmet resources are limited and they are not frequently used in routine clinical practice, we suggest avoiding masks with vent holes and adding a filter between the mask and the vent valve to reduce viral transmission. Patient beds should be at least 1 m from one another and the ward air circulation rate needs to be increased [7] . For patients with suspected COVID-19 infection receiving long-term respiratory support at home, it is recommended that they stay in a single, well-ventilated room to avoid potentially infecting their family members. World Health Organization. Novel Coronavirus (2019-nCoV). Situation Report-28 The Novel Coronavirus Pneumonia Emergency Response Epidemiology Team. [The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) in China] (in Chinese) Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Evaluation of droplet dispersion during non-invasive ventilation, oxygen therapy, nebuliser treatment and chest physiotherapy in clinical practice: implications for management of pandemic influenza and other airborne infections Exhaled air dispersion during high-flow nasal cannula therapy versus CPAP via different masks Exhaled air dispersion during noninvasive ventilation via helmets and a total facemask Infection Prevention and Control during Health Care when Novel Coronavirus (nCoV) Infection is Suspected. www.who.int/publications-detail/infection-prevention-and-control-during-health-care-whennovel-coronavirus-(ncov)-infection-is-suspected-20200125 Date last updated