key: cord-1000905-r3egup0n
authors: Pran, Lemuel; Baijoo, Shanta; Slim, Hani
title: Viral Induced Thrombosis, novel Corona Virus
date: 2020-05-11
journal: J Vasc Surg
DOI: 10.1016/j.jvs.2020.05.001
sha: be2c324a1c12fa7699939de5114d770564014a78
doc_id: 1000905
cord_uid: r3egup0n

nan

Induced Thrombosis becomes even more important. The phenomenon of vascular thrombosis as 5 described by Virchow involves changes in either the vessel, blood flow or the fluid constituents 6 4,5 . Therefore, any factor which can alter the homeostatic mechanisms of these three components 7 will predispose to thrombosis. There are reports in the literature which provide insight on 8 changes predisposing an individual to thrombosis as a result of severe viral infections 6,7 . 9

The CoV is a Beta Coronavirus (enveloped single-stranded RNA virus), of which many 10 symptoms involve the respiratory and cardiac systems in patients requiring hospitalization 8 . 11

There is emerging evidence to support the trends of increased morbidity and mortality from the 12

CoV that occurs more frequently in older individuals with co-morbidities 9,10 . Furthermore, in the 13 older population with co-existing medical illnesses, the combination of severe infection with the 14 CoV can result in an increased tendency for intra-arterial thrombosis. the definitive management can result in limb loss, intra-abdominal catastrophe or even death. 20

In conclusion, the authors wish to highlight the entity of Viral Induced Thrombosis and 21 intra-arterial thrombosis in association with severe viral infections, especially in the CoV 22 positive patient. We wish to encourage our colleagues across all fields of speciality, to have a 23

Cellular Pathology as Based upon Physiological and Pathological History. 12 [Tr. from the 2nd Ed

) AR. Virchow and his triad: a question of attribution

Understanding Infection-Induced 16 Thrombosis: Lessons Learned From Animal Models

Review: Viral Infections and 20 Mechanisms of Thrombosis and Bleeding

Evolution of the novel coronavirus from the ongoing Wuhan outbreak and 1 modeling of its spike protein for risk of human transmission

Correction to : Clinical predictors of 3 mortality due to COVID -19 based on an analysis of data of 150 patients from Wuhan

Intensive Care Med

Epidemiological and clinical characteristics of 99 cases 6 of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study