key: cord-1006592-4ym1hvyn authors: Kumar, Manish; Manna, Suvendu; Jha, Amritesh Kumar; Mazumder, Payal; Rastogi, Neeraj title: Game of Transmissions (GoT) of SARS-CoV-2: Second Wave of COVID-19 is here in India date: 2022-03-19 journal: Curr Opin Environ Sci Health DOI: 10.1016/j.coesh.2022.100355 sha: a75a09da110ff0ba3fa5a40f4e0e1e519cd298f1 doc_id: 1006592 cord_uid: 4ym1hvyn Corona Virus Disease (COVID-19) pandemic had taken the humankind by surprise, yet the world laid out a historical battle against all the odds. Laboratory findings have never been so rapidly made available to common public and authorities. Experimental data on COVID-19 from across the globe was directly made accessible worldwide. The second wave of the pandemic in India caused unprecedented havoc and it can be stated that all the knowledge of the game of transmission of COVID-19 acquired and shared was not played with right precision and preparations. Rapid spread of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in the second phase made us rethink if the choice of information given to the common people pertaining to the selective transmission restriction pathways with pressing concern on lethality were inadequate. Most of the governmental and non-governmental organizations (NGOs) including the World Health Organization (WHO) recommended droplet-based and airborne transmission restrictions as the major steps to control rapid spread of the virus. While, no caution was advised for other plausible pathways like sewage, wastewater-based and non-ventilated indoor air-based transmissions, which are still unknown or not well investigated, and are equally dangerous. The main focus of this article is to analyse the past development about SARS-CoV-2 transmission pathway related recommendation(s) provided by WHO and track the trajectory to alert all the concerning stakeholders and policymakers to rethink and to collect adequate scientific data before they recommend or neglect any specific or all the possible transmission pathways to control the spread of infectious agents further. world laid out a historical battle against all the odds. Laboratory findings have never been so 28 rapidly made available to common public and authorities. Experimental data on COVID-19 29 from across the globe was directly made accessible worldwide. The second wave of the onset of the pandemic, has once again become crucial to assess its true potential [1] . Although 52 globally followed isolation among the population do have a potential of restricting the spread 53 of the disease, its effectivity lies in the detection of asymptomatic infected individuals [2] . 54 Therefore, isolation should also be followed by rapid contact tracing and clinical testing. There 55 are several documented modes of SARS-CoV-2 virus transmission including fomites, aerosols, 56 droplets, etc. Here, we are trying to explore other plausible routes of transmission that can 57 lead to further spreading of the virus. Further, referring to very popular proverbs viz., "Prevention and protection is better than cure" and "It is definitely better to be safe than to 59 be sorry", until extensive research data nullifies or ascertains pathways of transmission, we 60 believe that all the probable routes/modes should be considered and relevant guidelines 61 should be formulated which can be updated upon availability of newer data. In order to get a 62 better understanding of the various transmission channels and the probable dynamics SARS- 63 CoV-2 has been compared to its counterpart viruses [3] . 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