key: cord-1010194-id1gou5e authors: Singh, Abhishek title: Noninvasive versus invasive ventilation: one modality cannot fit all during COVID-19 outbreak date: 2020-07-08 journal: Korean J Anesthesiol DOI: 10.4097/kja.20227 sha: aa2ebf884167a895bde2f3cb2b9baabf87b74713 doc_id: 1010194 cord_uid: id1gou5e nan monary vascular autoregulation has been implicated for hypoxemia and poor oxygenation during the early stages of ARDS, using the common protocol of applying high positive end-expiratory pressure to all the patients might aggravate the lung injury resulting in a poor outcome. Disadvantages of invasive ventilation: The procedures associated with invasive ventilation such as preoxygenation, bag-mask ventilation, intubation or extubation, and suctioning of the airway are aerosol-generating and pose a serious risk of infection for HCPs. Ventilator-associated complications such as lung injury, pneumonia, and prolonged intubation should also be considered before making the choice for the invasive or non-invasive ventilation approach for COVID-19 associated ARDS. We hereby conclude that there is a certain population of COVID-19 patients with ARDS having a particular demographic profile (younger age and lesser comorbidities) who may benefit from an early and meticulously supervised NIV procedure instead of blindly intubating all patients with hypoxemia and ARDS. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study In: StatPearls [Internet]. Treasure island (FL): StatPearls Publishing Effectiveness of noninvasive positive pressure ventilation in the treatment of acute respiratory failure in severe acute respiratory syndrome Lung recruitability in COVID-19-associated acute respiratory distress syndrome: a single-center, observational study No potential conflict of interest relevant to this article was reported.