key: cord-1032644-mi208446
authors: Deniz, Rabia; Çağatay, Arif Atahan; Gül, Ahmet
title: Letter: is pneumococcal vaccination safe during the COVID‐19 pandemic?
date: 2020-08-14
journal: Aliment Pharmacol Ther
DOI: 10.1111/apt.15903
sha: 4ddf2200dd34014231238114591db7a280d88e7c
doc_id: 1032644
cord_uid: mi208446

LINKED CONTENT This article is linked to Al‐Ani et al papers. To view these articles, visit https://doi.org/10.1111/apt.15779 and https://doi.org/10.1111/apt.15940

Although immunisation of especially vulnerable populations has been shown to be protective for fatal bacterial complications in elective conditions, pneumococcal vaccination of a patient with a probable or existing COVID-19 during pandemic could cause a hyperinflammatory response by further activating the NLRP3-inflammasome and progression to the cytokine storm, ARDS and death. Therefore, because of the safety concerns, we consider that vaccination decisions, especially for pneumococcal vaccines, should be given very carefully during the pandemic until further data become available.

Declaration of personal interest: None. 

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