key: cord-1032808-txe3beav authors: Alberca, Gabriela Gama Freire; Alberca, Ricardo Wesley title: What is the long‐term clinical significance of anti‐SARS‐CoV‐2‐specific IgG? date: 2020-11-01 journal: Influenza Other Respir Viruses DOI: 10.1111/irv.12825 sha: 7c5246194fbfc585172c3a6a7b9e809d1647bf6a doc_id: 1032808 cord_uid: txe3beav nan To the Editor: We read with great interest the article "Clinical significance of SARS-CoV-2-specific IgG detection with a rapid antibody kit for COVID-19 patients" by Chong The ability to prevent the re-infection of anti-SARS-CoV-2 IgG produced after a natural infection by SARS-CoV-2 is yet to be determined. Therefore, we hypothesize that the severity of the initial infection may influence the anti-SARS-CoV-2 antibody production and its viral elimination efficacy. In addition, a few confirmed cases of re-infection have been reported. [10] [11] [12] The two main hypotheses would be a mutation or The authors declare that they have no conflicts of interest. The peer review history for this article is available at https://publo ns.com/publo n/10.1111/irv.12825. The data that support the findings of this study are available in the referenced material of this article. Clinical significance of SARS-CoV-2-specific IgG detection with a rapid antibody kit for COVID-19 patients Distinct features of SARS-CoV-2-specific IgA response in COVID-19 patients Dynamics of anti-SARS-Cov-2 IgM and IgG antibodies among COVID-19 patients Antibody responses to SARS-CoV-2 in patients with COVID-19 One case of coronavirus disease 2019 (COVID-19) in a patient co-infected by HIV with a low CD4+ T-cell count A human monoclonal antibody blocking SARS-CoV-2 infection Human neutralizing antibodies elicited by SARS-CoV-2 infection SARS-CoV-2 environmental contamination associated with persistently infected COVID-19 patients Neutralizing antibody production in asymptomatic and mild COVID-19 patients, in comparison with pneumonic COVID-19 patients COVID-19 re-infection by a phylogenetically distinct SARS-coronavirus-2 strain confirmed by whole genome sequencing A case of early re-infection with SARS-CoV-2 Case report: recurrent clinical symptoms of COVID-19 in healthcare professionals: a series of cases from Brazil Rapid decay of Anti-SARS-CoV-2 antibodies in persons with mild Covid-19 Longitudinal analysis of severe acute respiratory syndrome (SARS) coronavirus-specific antibody in SARS patients Evasion of antibody neutralization in emerging severe acute respiratory syndrome coronaviruses