A BRIEF AND ACCURATE TREATISE, CONCERNING, The taking of the fume of TOBACCO, which very many, in these days, do too too licentiously use.  
In which, the immoderate, irregular, and unseasonable use thereof is reprehended, and the true nature and best manner of using it, perspicuously demonstrated.  
By TOBIAS VENNER, Doctor of Physic in Bath, in the Spring and Fall, and at other times, in the Borough of North Petherton near to the ancient Haven town of Bridge-water in Somersetshire.  
AT LONDOON, Printed by W. I. for Richard Moor, and are to be sold at his Shop in S. Dunston's Churchyard in Fleetstreet. 1621.   

ILLUSTRISSIMIS VEREQVE GENEROSIS VIRIS, DOMINO FRANCISCO HELENA, ET DOMINO FRANCISCO ROGERS, MILITIBUS.  
Hoc de Tobacci fumo opusculum,  
In Devoti animi testimonium, offered, dedicat, consecrat  
Tobias Vennerus, Medic. Doctor.   

it, 
The nature of Tobacco.  it is hot and dry in the third degree, and hath a deleteriall, or venomous quality, as I suppose: for it being any way taken into the body, it tortureth & disturbeth the same with violent eiections both upward and downward, astonisheth the spirits, stupifieth and benumbeth the senses and all the members. This noisome faculty of Tobacco proceedeth not from the temperature of it, but from the very essence of its substance. As for the stupifiing or benumbing quality thereof, it is best perceived upon the taking of the fume at the mouth: for thereupon followeth a drunken-like lightness of the head, and especially if it be much taken at once, a benumbing sleepiness of the limbs and senses. Wherefore Tobacco, though it be in taste, biting, and in temperature, hot, hath notwithstanding a benumbing quality; which, because it cannot depend of an extreme cold quality, the herb being very evidently hot, it followeth, that it is hot and benumbing, not benumbing by reason of its temperature, but through the property of its substance. There is in the juice of this herb an excellent digesting, mundifying, and consolidating faculty; by means whereof, it is of ineffable force for the speedy curing of any wound or cut in the flesh, or sores, ulcers, scabs, etc. for which it is worthy of very great esteem, and not much for any other property to be magnified and respected (as I conceive.) And thus much briefly concerning the nature of Tobacco.  
Before I pass to deliver mine opinion concerning the use and faculties of the fume, 
An objection of our vulgar Tobacconists.  I must clear an objection of our vulgar Tobacconists, which I seem to hear them make against the noisome qualities that I have averred to be in Tobacco, saying; that upon the taking thereof they find no tortures and violent eiections, or stupifying of their members and senses. To whom I may answer, 
Solution.  that the immoderate use of Tobacco hath made them Insensiles, without sense. But let it be admitted, that upon taking of the fume, they find not those malignant effects; yet it convinceth not my assertion, because that by long use and custom, it becometh familiar to their bodies. And thus much by the way to our licentious Tobacconists, who spend and consume, not only their time, but also their health, wealth, and wits, in taking of this loathsome and unsavoury fume. Now I come to speak of the smoky fume and faculties thereof, which is taken through a pipe, for that purpose, into the mouth, and thrust forth again at the nostrils, and is of some also sucked into the stomach and breast, against all diseases, especially such as are gotten by cold, or that proceed from a cold and moist cause.  
The Indians, 
Sleep and vain dreams, two effects of Tobacco for which the Indians used it.  from whom we received this manner of taking Tobacco, were (at the first) only wont to take it at such times, as they felt their bodies wearied with much labour and exercise, or would presage of things to come: for the fume procuring first a drunken-like lightness of the head, and thereupon sleep, with sundry phantalmes or visions, was the cause that upon their awaking they found themselves (through their sleep) greatly eased, and refreshed, and could, by reason of the somnorine visions which this fume doth greatly occasion, presage (as they fond conceived) the event of any business, or matter of importance, that they desired to know, or were delighted in.  
First they took the dried leaves of Tobacco, and cast them on the coals, than they received the smoke of them at their mouth and nose with a kane, and continued the taking thereof so long, till that they fell into a drunken trance and sleep, wherein they continued as dead three or four hours, according to the quantity of smoke that they had taken. The fume having done his work, they awakened out of their sleep, and found themselves eased and lightened, in such sort, as that they were able to return to their labour or exercises, as lustily as before: and this they did always when they found themselves wearied, or were (as I have said) desirous to foreknow, what might be the success of their business, by means of the vain dreams and visious, which this fume suggesteth.  
But this custom of taking the fume, hath so far bewitched them (as also it hath and daily doth many of our people) as that they also oftentimes, take it for wantonness and delight, wherein they have so great a pleasure, as that they desire nothing more than to make themselves drunken and drowsy with Tobacco. And thus much for the original of the fume. I will now leave the Americans, and come to our Europeans, who (well-near) use the fume of Tobacco with as much excess as they do.  
Many of our people, and that of all sorts, do greatly affect the taking of Tobacco; but few of them respect whether it be profitable to their bodies: for most take it, rather for custom and delight, to entertain and pass away the time, then for any such necessity or utility that they have of it: whereby it cometh to pass, that some judge very hardly of tobacco's fume, and utterly disclaim the use thereof. In consideration whereof, I was moved to publish this Treatise, showing therein the faculties and right use of the fume of some (as I know) greatly desired, and withal, taxing the ignorance, or rather petulancy of many, that in these days do take it without any respect had of the time, age, or constitution. A work (I hope) no less pleasing, then profitable.  
For mine own part, I confess, that though I am in no wise delighted with the fume of Tobacco, partly for the malignity of its nature, but especially, because of the detestable savour or smack that it leaverh behind upon the taking of it: yet I do not altogether condemn the use thereof (for I sometimes in case of necessity, as when I am afflicted with rheums, take it myself, especially prepared, as I will hereafter show) but rather approve it as necessary and profitable for the rheumatic, and such as are by temperature, cold, so as it be taken in congruent manner, that is, both moderately and seasonsbly, as shall be hereafter showed, for it helpeth the brain that is over cold and moist, 
The virtue's o● tobacco's fume.  reducing it by its heating and drying faculty unto a temperuture: it taketh away rheums and windiness of the head, and is profitable for all cold effects of the brain and sinews, by resolving and consuming the crude and windy superfluities of those parts: it doth (for the time) expel melancholy, and excite lumpish spirits: it helpeth pains of the teeth, swellings of the gums, and aches of the joints: it preventeth putrefaction of humours, by drying up the crudities of the body, and is very profitable upon taking of cold, and for all cold and moist effects of the stomach, breast and lungs. It is a speedy remedy upon a surfeit, 
Imbibitus, that is, taken down.  by making a sudden evacuation both upward and downward of such things as are contained in the stomach, and by the like reason it doth, in an instant, remove windy torments of the stomach, and bowels, that proceed of crude humours, and helpeth the fits of the mother: in a word, it is (being rightly used) available against all cold and moist distemperatures. But to such as are not of a cold and moist constitution, nor affected with rheums, it is not, though it be only retained in the mouth, and poured forth at the nostrils, but by way of precaution, and that with good advisement to be permitted, as I will by and by show, and the reason is, because this fume which is hot and dry in the third degree, ascending to the brain, doth not only greatly heat and distemper it, but also the animal spirits, whereupon oftentimes the senses are confounded, and the understanding perverted.  
As touching the taking of the fume down into the stomach and lungs, 
This custom of taking the fume down  I utterly disclaim as pernicious, 
into the stomach & lungs very pernicious  except it be done by way of Physic, one or another of the aforesaid affects, impensively requiring it, both by reason that it is of a very turbulent and sickly operation, and also, because it being excessively hot, over heateth, and drieth the liver, marreth the concoction of the meats, and deturbeth them undigested from the stomach, if it be taken before they are concocted. Moreover, the lungs which are the flábell of the heart, being by nature (in regard of their great use and continual motion, of soft and spongy substance, are by the immoderate heat and sircitie of this fume, quickly dried and coarctated, and consequently become unapt for motion, to the great offence of the heart, and ruin at length of the whole body. Hence it may appear, in how great an error they persist, that usually, or for every light occasion, imbibe or take down this fume.  
Now that which hath been spoken concerning the use of this fume, is not so precisely to be taken, as that it is at no time lawful or convenient for such as are not by nature rheumatic, or cold by constitution to use it: for it is sometimes allowable for every one, except for him that hath a dry distemperature of the brain, to take this fume by way of prevention. For example sake, if any one having not a dry constitution of the brain, shall travel, or take a journey in misty, stormy, and rainy weather, especially in the winter season, I say, that it is expedient for him, although he be not rheumatic, or of a cold temperature to take three or four draughts of this fume so soon as he shall be entered into his house or Inn, for the preventing of rheums, or other harms that may chance to him by means of the grossness or impurity of the air.  
But me thinks I hear many that are not by nature rheumatic, 
An objection of our vulgar Tobacconists.  nor of a cold temperature of body, lovers of this fume, or that I may more rightly speak, abusers, and luxuriating in this kind of evil, for cloaking of their vicious custom, to object against me after this manner. We find by daily experience, that the fume of Tobacco doth draw from us very many rheumatic humours: wherefore the use thereof is not only allowable and good for the rheumatic, and such as are of cold temperature. I do deny the argument; and also reject their experience: 
Solution.  for their lewd and preposterous custom in taking this fume is convenient for no constitution or state of body: for, one while they take the fume, another they drink, and so continue by turn, until they fall asleep, vomit, or be drunk: wherefore it is no marvel that upon the use of the fume they excrete very many rheumatic superfluities, seeing that by this their preposterous and unreasonable mingle-mangle of smoke and drink, far more crudities and superfluities are bred, then can by virtue of the fume be consumed or excreted, as it is to be seen in them that are given to Tobacco, & the Pot, whom you may see to have tumid and smoky faces, with turgid and flatulent bellies.  
here also some, I know, which are delighted with the drinking down of this fume, that I may so speak, 
Another objection.  will object against that which hath been spoken against that manner of taking it, namely, that upon the taking of it down after meat, they find no perturbation or offence, but rather, very great commodity, by furthering the concoction. I must tell them, that in this they are grossly deceived: First, because their daily custom of imbibing the fume taketh away the sense of perturbation; for by use and custom, any thing (though contrary) is made familiar unto Nature, as I before have touched: Secondly, they are no less deceived, thinking by imbibing the fume, that the concoction is furthered, being not able to distinguish between concoction and distribution: for it is the worst thing, and most pernicious to the body, to occasion the distribution of the meats before they are concocted in the stomach; which they do, that imbibe or drink down the fume after meat. And verily, the cause of this their error, is some emptiness of the stomach, or provocation to stool, which they feel upon the receiving of the fume, not considering, that this their emptiness and ill distribution of the meats, and consequently, provocation to stool, proceed from the purgative faculty of the fume. Wherefore I would have them to understand, that though they seem to be well for the time, either by reason of their youth, or of a strong constitution of body, that this preposterous taking of the fume, will upon the sudden, ruin the state of their body, by spoiling the stomach, destroying the concoction, and filling the whole body with crude and noisome superfluities..  
I 〈…〉 shall again urge to shun these discommodities, and maintain another custom no less pernicious, that they will take the fume about three or four hours after meat, when the concoction is effected, for deturbing or driving down the relics of the meats, and crudities that shall be in the stomach, I would have them to know, that the hurt will be far greater than the profit: for besides that, in this they pervert the operation of Nature, they greatly also annoy the lungs, disturb and infringe the spirits, corrupt the breath, and destroy the languifying faculty of the liver. I marvel verily at the madness of these men. For, what is there in the fume that should so greatly occasion delight? Not the smell, because it is unpleasant, much less the savour, for it is stinking and fuliginous.  
Besides these idle affectors of Tobacco, there are also some who are grave and seemingly wise and judicious, that take it moderately, and most commonly at fixed times; but with its proper adjunct, which (as they do suppose) is a cup of Sack, and this they think to be no bad physic; nay, they so rely upon this sacred medicine, as the most of them become detractors both of physic and Physicians, for which cause they shall not pass without my tax. As for Sack, it is without all controversy, very helpful, comfortable and agreeable to man's nature, as I have showed in my Book which is entitled, Via recta ad vitam long am, of this years' Impression: Tobacco is not so, but rather oftentimes hurtful, especially if it be no judiciously used. But, whether Sack be good to be taken upon Tobacco, I will hereafter (notwithstanding these detractors, for the good of others) demonstrate.  
As for these Cynic detractors (for such you shall find most of them to be) 
a There is also no other reason why very many of our people, in their sickness, expose their bodies to be corrupted, I cannot say cured, to ignorant usurping Pothecaries, and other base illiterated Empirics, who are (contrary to the Laws) every where permitted to exercise Physic, to the dishonour of God, disgrace to the Faculty, hurt of our People, and shame of our Nation,  I must tell them, that this their absurdity proceedeth from their ignorance of the great and admirable mysteries of the noble Art of Physic; or for that they are slaves to their purses, and therefore seek not in their necessities, physicke-helpes, and counsel from such as are learned in that faculty; or else, it is because they deem all expense lost, besides that which adorns the back, or oblectate the palate and throat. And so I leave these to their physic, and the common Tobacconists to their sleeping between the Pot and the Pipe, and come now again to show the right use of Tobacco.  
Although it be apparent, by that which hath been hitherto delivered, that the taking of Tobacco is only convenient for cold and moist bodies, that the often and daily use thereof is only allowable for them that have their stomach, breast, brain and sinewy parts exceedingly cold, and stuffed with crude and rheumatic humours, and also that it is sometimes tolerable for others, by way of prevention; yet the knowledge of these things, without the true use and application of the fume, as namely, when to use it, how often, in what manner and measure, and what to observe after the taking of it, is of small purpose: for it may (being taken without respect had of these circumstances) prove more hurtful, then beneficial unto him that taketh it. Wherefore I wish him that desireth to have the true use of Tobacco, to receive from me, and carefully observe ten precepts in the use thereof.  
The first is, 
Ten precepts to be observed in the use of Tobacco.  that it be most commonly taken mornings fasting, after a little stirring of the body, and also sometimes about half an hour before dinner and supper, but especially at the time of going to bed, in whom the condition of the body, as a cold and moist constitution; and some accidences, as rheums, catarrhs, heaviness of the head, and crudity of the stomach; or circumstances, as a moist, foggy, and waterish season, shall for the preservation of the health, require the use thereof.  
2 The second is, that the taking thereof be chiefly observed after travelling in misty foggy and rainy weather, because it preventeth catarrhs, and rheums, and taketh away all hurts that are wont, by rcason of the humidity and 〈◊〉 of the air, to happen to the head and other parts. For the taking thereof at such time, is convenient for every state of body, except where there is a dry constitution of the brain, as hath been formerly showed.  
3 The third is, that it be taken with moderation, not (at the most) exceeding the quantity of a pipe full at a time; for every thing which is superfluous, is very adverse to Nature, and nothing more than Tobacco.  
4 The fourth is, that at meals between the eating, it be at no hand taken, as many very foolishly do, because it utterly interrupteth and marrerh the concoction.  
5 The fifth is, that it be not taken within four or five hours after meal, except a peculiar state of the body shall necessarily require the taking thereof presently upon the meal, and that only in two respects: The first is, for the imbecility of the native and digestive heat in some, which may not be a little comforted by the translation of the heat of this fume, mediantibus nervis, from the brain to the stomach: The second is, for the consuming of vapours, and preventing of their hurts, which in others are (by reason of an ill disposition of the stomach) immoderately wont to ascend after meal: for by means of the fume detained in the mouth and cavities of the brain, those superfluous vapours are in part consumed, the brain, which by nature is over cold, and moist, heated and dried, and consequently, not so soon annoyed by the vapours which do ascend unto it.  
6 The sixth is, that you drink not between the taking of the fumes, as our smoky Tobacconists are wont, because thereby the operations of the fume are hindered, and more superfluities commonly bred, then can by the efficacy of it be consumed.  
7 The seventh is, that you eat not, nor drink any thing within a quarter of an hour after the taking of the fume, but allowing that space for the operation of it, you may then wash your mouth with Beer or Wine, to take away the fuligivous savour of the fume, and also drink a draught of Sack, if the stomach shall be cold, or abound with crude and flatulent humours, and so go to your meal, if it shall be the time of your repast. For, to wash your mouth, or drink presently upon the taking of the fume, doth much hinder the operation of it: or, in stead of washing your mouth, you may presently, upon the taking of the fume, rub your tongue, palate, and gums, (which I always hold fit to be observed) with a dry napkin, and if it be also heated, the better, especially in cold and rheumatic seasons, and afterwards chew in your mouth something of an aromatical savour, as cloves, or the roots of Galingall, or the flowers of Rosemary, and Sage when they may be had, etc. or the conserves of them: for these, and such like, do not only take away the fuliginous and stinking savour of the fume, but also give comfort to the brain and spirits. And upon the doing hereof, if it be not before meals, it is specially good to swallow down abo●t the quantity of a prune or two of the conserve of red Roses. Tabulae Dianisi, which you may have from the Apothecaries, are also very good to be eaten upon the taking of Tobacco, the mouth being first washed as aforesaid, for they correct the evil savour and smell of the fume, make the breath sweet, and also resolve windiness of the stomach. I commonly use, upon the taking of Tobacco, to swallow down a spoonful of a pectoral and cephalic syrup made for the purpose, which doth forthwith remove the offensive savour of the fume, and is withal, very profitable unto the stomach, breast, and head, & thereupon also, a quantity of the conserve of red Roses, especially at the time of going to bed.  
8 The eight is, that in drawing of the fume, you suffer it not externally to affect the eyes: for it is unto them, by reason of its smoky drying, and fuliginous nature, very offensive.  
9 The ninth is, that you warily draw the fume out of the pipe, not sucking it into your windpipe and throat with a sudden or strong attraction; for than it will exasperate the windpipe, and much offend and disquiet the mouth of the stomach.  
10 The tenth and last is, that you go not abroad into the air, presently upon the taking of the fume, but rather refrain therefrom the space of half an hour or more, especially if the season be cold, or moist, because the pores of the body being open, by means of the strong working of the fume, even to the uttermost and superficiary parts of the body, ineffable hurts may happen, by the sudden access of the air. Hence you may observe how idle and foolish they are, that can not travel without a Tobacco pipe at their mouth; but such (I must tell you) are no base Tobacchians: for this manner of taking the fume, they suppose to be generous: Let these fume-gallants enjoy their vanity, and for their better grace, it were good they were also attended with chimney-sweeping Lackeys.  
Now from that which hath been said, you may collect a twofold manner of taking of Tobacco, which ought to be altered and observed, according as occasion and the particular state of him that taketh it, shall require. The first is, a detaining of the fume only in the mouth, and thrusting of it forth again at the nostrils, for heating and drying of the brain, and for dissolving and dissipating of cold humours and superfluous vapours that reside in it. The other is a receiving of it into the stomach and lungs, 
The fume of Tobacco ought not to be taken down upon every light occasion.  for consuming & deturbing of crudities and windiness, that shall offend in those parts. But I advice, that the fume be suddenly taken down, and then neither, but some great necessity or extremity urging it, both because it offendeth the body with its violent operation, and also for that it may, by reason of its exiccating nature, be very hurtful to the lungs, liver, and melt, as I will by and by show. Wherefore my counsel is, that some safer remedy (if time shall permit) be used for consuming and deturbing of the flatulent crudities of the stomach and bowels.  
Whosoever therefore thou be that desirest to know whether the fume of Tobacco may be profitable or hurtful to thy body; thou oughtest first to consider, whether it be convenient for thy head: for if thy brain be over cold and moist, or abound with superfluous matter, than the detaining of the fume only in the mouth, and forcing it out at the nostrils, may be profitable unto thee: for by this means the fume ascending to the brain, doth not only by its heating, attracting and exiccating faculty evacuate and consume the superfluities in it, but also, in some measure, reduceth the same to its native temperament.  
But here by the way it is to be noted, 
Such as are affected with a dry distemperature of the brain, must very warily (when they are annoyed with rheums) use tobacco's fume.  that it may sometimes happen, that some may have their heads accidentally stuffed with rheumatic matter, although the brain itself be not in its native temperature excessively cold and moist, but is rather affected with a dry distemperature. Wherefore I adwise such, to take the fume with very great caution & moderation, as at one time not to exceed the quantity of six or seven draughts at the most, lest it should cause greater hurt to the brain and spirits, by increasing the dry distemperature of the brain, and incensing the spirits, than commodity in discussing and consuming the cold and waterish humours, wherewith the brain was accidentally oppressed, which in some I have observed to come to pass, that have without measure and judgement used this fume.  
Secondly, you must diligently consider whether the fume of Tobacco be convenient for the stomach, lungs, and liver. For, if crude and windy humours abound in the stomach and bowels thorough a cold imbecility of the liver; or if a cold distemperature, and thin, crude, and flatulent humours domineer in the lungs, than the imbibing also or taking down of the fume into those parts, may, so the stomach be empty of meats, be sometimes tolerable, yea profitable, especially for strong bodies, in case of extremity, and when no better remedy, at the instant, can be had: for by its heating, exiccating, and purging faculty, it somewhat correcteth the distemperature, consumeth wind, and forthwith expurgeth the offensive humours. But by reason of its turbulent and sickly operation, I cannot commend the often use thereof, nor at any time approve it to them that are of a weak and valetudinary state of body.  
here two cautions do offer themselves to be observed concerning the imbibing, 
Two cautions to be observed in taking the fume of Tobacco down.  or taking down the fume: the one, in respect of the lungs, the other, in respect of the lungs and liver too. For if the lungs be obstructed of a thick and clammy humour, or subject to such obstruction, than the taking down of the fume is very pernicious, because it doth by reason of its heat and siccity, more harden and condense the humour, by means whereof, it is altogether unfit to be excreted. From hence it is manifest, with how great prudence, 
Cautio practica  caution and providence, we are to use heating and drying remedies in affections of the lungs. In like manner also the taking down of the fume, is very pernicious to them that are affected with a dry distemperature of the liver, or lungs, although the stomach and intestines shall sometimes be annoyed with crude and flateous humours, because it will cause greater hurt by increasing the distemperature of those parts, than commodity in discussing and purging forth the crudities of the stomach and bowels: and therefore (in mine opinion) it is far better, in such case, altogether to abstain from taking down the fume, and to use a more safe and easier remedy.  
The like caution must also be observed in respect of the melt that is obstructed, 
Tobacco most pernicious to dr 〈…〉 like bo●ies.  or subject to obstruction, especially in them that are of a dry melancholic temperature, because the fume, by reason of its heat and siccity, doth not only greatly distemper them, but also causeth their blood to grow more melancholic, and to be adusted, and the melancholy humour that resideth in the spleen, as in its proper receptacle, to be indurated from whence diverse calamitous miseries do commonly arise. Wherefore I advice all such as are of a melancholericke constitution, utterly to shun the taking of Tobacco.  
But, that tobacco's fume may more effectually perform all the aforesaid commodities, and with less detriment, I advice that the rules of Tobacco be macerated or steeped two or three days in sack abundantly edulcated or sweetened with sugar, 
The preparation of Tobacco.  wherein Nutmegs, Cloves, Saffron, the roots of Sassafras, Calamus aromaticus, and of Galingale, Lignum aloes, knaps of Stickadove, the Flowers of Rosemary, Sage, and Lavender-spike, together with their knaps, Fennell seeds, and the excellent grains called Cubebe have been infused four and twenty hours, and afterwards strained from the liquour with a strong expression. All these things must be bruised a little, saving the Saffron, but the roots and Lignum aloes more than the rest, or sliced very thin, and for the quantities of them, and of the wine, it must be according to the quantity of Tobacco that you will infuse, wherein you can commit no error, so you take not above half a dram of Saffron to a quart of Wine: when the Tobacco shall be infused as aforesaid, take it out of the liquour, and reserve it for your use. If any shall also sprinkle it with a few drops of oil of anise or Fennel seeds, or rather, of Cloves, I will not gainsay it. For the fume, by reason of an Aromatical savour, which it acquireth by means of this artificial preparation, is more agreeable to the spirits, & doth, besides the aforesaid commodities, which it more excellently performeth, far less offend with its benumbing quality, ill smell, and fuliginous savour.  
Now, 
The discommodities of Tobacco, being immoderately and untimely received.  that I may impose an end to this business, I will summarily rehearse the hurts that Tobacco inferreth, if it be used contrary to the order and way I have set down. It drieth the brain, dimmeth the sight, vitiateth the smell, hurteth the stomach, destroyeth the concoction, disturbeth the humours, and spirities, induceth a trembling of the limbs, corrupteth the breath, exiccateth the windpipe, lungs, and liver, annoyeth the melt, scorcheth the heart, and causeth the blood to be adusted: Moreover, it eliquateth the pingui-substance of the kidneys, and absumeth the geniture. In a word, it overthroweth the spirits, perverteth the understanding, and confoundeth the senses with a sudden astonishment and stupidity of the whole body. All which hurts I affirm, that the immoderate and intempestive use of Tobacco doth effect, both by reason of its temperament, but especially through the property of its substance: wherefore the use of it is only tolerable by way of physic, not for pleasure, or an idle custom.  
To conclude therefore, I wish them that desire to have mentem sanam in corpore sano, altogether to abandon insanam praeposterumque Tobacci usum. This is all which seemed good unto me to be written of tobacco's fume, partly for showing the right manner of using it, but especially for reprooving the too too licentious liberal, and intempestive taking of it, which very many, in these days) do to their own ruin lewdly, and for want of better employment, foolishly affect.  
FINIS.