Membrorum Principalium Apostasia: OR, A SHORT VIEW OF Those many Diseases and Infirmities which proceed from a Defection, or Falling away of the Principal Members or parts of the Body, from the performance of their several Offices and Functions; Together with Their CURES, By the Matchless Tinctura Caelestis: A Medicine Tightly prepared and fitted to give Relief in such Extremes, and of sufficient Virtue and Efficacy to reduce those vitiated parts to their former state; and thereby Radically Cure 〈◊〉 ●●st deplorable Diseases in Men, Women and Children: With several Instances of some Eminent and Memorable Cures, of late wrought by it.  
By J. Barrow M. D.  
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Membrorum Principalium Apostasia: OR A SHORT VIEW of those many Diseases and Infirmities, etc.  
IT is the Office of Medicine; saith Barthol. Peraulcis; Quod deest in humano corpore sarcire, etc. to repair what is defective in man's Body, and withdraw what is supflu us. This indeed is the main Scope and Design of Physic. This point, i● the Centre of all the Studies and Labours of the most Learned Physicians; and th● utmost End and Perfection of this most renowned Art. Hence it was that Medicine▪ justly prepared, and duly administered, were by Herophilus called, Manus Deorum The Hands of the Gods; intimating a certain Beam of Divinity, even in these mean● parts of the Creation, the inferior Classes of Natural Bodies, by reason of that Miraculous Efficacy, that admirable and unaccountable power and virtue which was found i● them to repair and make good, the continual decays of humane Bodies, and thereby support and prolong the Health and Life of Man. For this reason I was moved (with ● desire to do good to all, but especially the poorer sort, who were not able on all occasions to apply themselves to a Physician) to publish this most Generous Medicine m● TINCTURA CAELESTIS.  
A Medicine! which, from its preparation and operation, I can with good assurance warrant, to answer those great Ends in Physic before mentioned and by many signa Experiments, in several years late past demonstrate: Some of which I shall here mention, but all I cannot in this narrow compass. I say, those two qualifications of a goo● Medicine, are Eminently visible in this; as first, it doth, det●●here superflua, draw a way all superfluity of humours, which are the causes and matter of divers Diseases: An● next, it doth Quod deest sarcire, repair what is defective, by adding strength and vigour to the sickly and enfeebled Body, and that with all possible ease and security For the Composition of this excellent Tincture (as it is wrought with that Care an● Skill (let me speak it without boasting) that becomes an Artist, so it is manage with that caution and regard to all constitutions, that all persons from the Cradle to th● Crutch, may safely and familiarly use it. Yet it is a brisk vigorous Medicine; word throughly and to the purpose gives plentiful Stools and Urine; without any uneasine● sickness, or gripping, as is usual with most purging Medicines: Yet (Note) one singular property (which it claims above others) where it meets with a very foul stomach it throws up by one Vomit, or two at most, a deal of filthy slime, and tenacious Phlegm and Choler, working off the rest downward, with much pleasure as well as profit t● the Patient.  
Upon the first Reception into the stomach, it is carried forth throughout all th● ways and passages of the Chyle (that is, an extract of the first concoction of the Food whereby it perfecteth the Concoctions, carries off all crude, or raw undigested matt●● which disturbs or deprave them, restores lost Appetite preserving the stomach, a● parts subservient unto it in a due disposition, to receive, retain, and properly distribute a good and sound nourishment, to the whole, and every part of the ●ody, with 〈…〉 〈◊〉 〈◊〉 toting it by hasty and ●●●●able flux of t● ●●y: dispersing all Fumes, Vapours, unpleasant belchings, puffing up, or stopping of the stomach: Proceeding farther and mixing with the Blood, it is carried therewith in it inculate motion throughout the whole Body, preserving the whole Mass, sweet, pure and untainted, comforting the Vitals, or Spirit of Life; and being 〈◊〉 high Cordial, helps against fainting, swooning, cold sweats, and trembling of the Heart, and the like Effects, caused by loss or disspation of the Spirits: It reacheth Ventricles of the Brain and Nerves, promoting the free passage of the animal Spirits and Nutricious Juice, ●uts off the Fountain of Catarrhs, or Rheumatic Defluxions, which fall upon the Joints and Muscles; and so turns off the Head-spring of Rheumatisms, Gout and Arthritick ●ains, which according to Fernelius (who glories that he only sound it out) fall from ●he Head upon all the parts so affected.  
It opens the obstructed Liver and Spleen, cleanseth those exile or narrow passages of the Lacteal Veins, unloads the Mesentery, Pancreas and Gall; all which are mutually concerned in Sanguification, or forming the Blood; and thus cures the Diseases of those ●arts so vitiated, as, cachexy, or evil habit of Body, Dropsies, Jaundice, Colic, Inflammation, Obstructions, Vapours, of Wind, shooting in●o the Sides and Back, and causing very sharp Pains there, it helps those who are Hy●●●●●●ack, though to a degr●● of Madness, and many other Diseases arising ●rom th● 〈◊〉 ●ses, which cannot b● treated of in this narrow Limit of discourse; in the Cures of which this N●ble Tincture hath wonderfully signalised its machless Virtues, of which I could give many instances, which daily occur, but must be contented to ●ive but 〈◊〉, and omit many for Brevity sake. One remarkable Cure was wrought upon  
The Mother in Law to Mr. Joseph Pluckrose, Glas●●●er at Fleet-bridge in Fleetstreet a Gentlewoman very ancient, who had long suffered under an evil habit of Body, with ●indy Fumes and Vapours, Obstructions of the bowels, inward pains, etc. but especially the faculty of her stomach deprav●d, appetite and digestion so weakened, that her food 〈◊〉 he usual passage, but was daily thrown up by vomiting, in which condition she had 〈…〉 a●uished, even to despair of recovery, till she took of my Tinctura Caelestis, by w●●●, with God's assistance; she soon recovered her former health, which continues to this d●y whereupon several of their Relations made use thereof, and sent quantities to their Friend's 〈◊〉 ●he Country who all found the like effects, to their great benefit and satisfaction.  
Another great and memorable cure was done upon one— Holsworth of Marlborough ●n Wiltshire, by Trade a Blacksmith (but a man Eminent in that Town, & all the Country about for some famous passages in his Life.) He lay long sick of a Dropsy, which was attended with great swell all over, difficulty of breathing, prostrate appetite, and the extremity of the usual symtoms of that prodigious disease, all advices and means used for his recovery proved ineffectual and death only was expected to end the contest between the disease and almost vanquished) Nature, till happily meeting with my Tinctura Caelestis, in the ●ands of Mr. Robert Butcher a worthy person of that Town: He took of it, according to the Direction of this Paper, and in a short time was restored to perfect health and continues lusty and strong; since which he occasionlly coming to London, came to visit me, ●nd gave me an account of disease and cure, which (next to Divine providence) he owned my Tincture only.  
Furthermore, in Diseases of the Reins, ureters and Bladder, as also the Seminal Genital Parts Its virtues are so great, that, all that I am able to say in my Praises of ●s incomparable Tincture, cannot come up to its deserved Character. But this I must 〈◊〉 (and modestly to) that 〈…〉 ●er and efficacy, to cleanse and scour those parts, and deliver them from all mann●● viscous matter, which is apt to be generated there and cause many violent Diseases; 〈◊〉 Obstructions, Inflammations, Ulcers, Run and Wastings even to the Consumption of th● whole strength and substance of the body: But especially in that most deplorable Disease, that can happen to miserable Man, the STONE; it is of unparalleled Virtue & Use. And though I will not say, that upon the present taking, this Tincture will forthwith break the Stone in pieces as with a Hammer, nor will any Man who knows what he says, affirm it of any one or all the Medicines in the World: But its great Operations are exerted by rectifying the depreved quality of the Kidneys, abolishing that matter of which the Stone is form, laying open the passages of the ureters that were obstructed, and making them thereby more f●ee and opportune to the draining away and expelling that lapidescent matter: Nature itself being thus relieved and assisted, will find it no hard matter to ease itself; And the Stone, for want of such matter to supply its growth, will be apt to waste and moulder away, and by the powerful impulse of this Noble Tincture, flow out in smaller particles with the Urine, as hath been proved by sufficient Experience, and may be confirmed by substantial Testimonies; among many I will here incert one from Mr Robert Butcher of Marlborough before mentioned, a Man of unquestionable Reputation and Integrity; I give it you in the words of his Letter.  
Your Tincture generally doth good, and answers people's Expectations: Here was an Old Man of about 70 Years of age lay very bad with the Stone, he took one Glass, and the next day brought away several stones of a great bigness, two of which I have in my house.  
I shall add one instance more upon this Subject. A Minister of a Town within 3 or 4 Miles from Southampton, coming to London, came to me, to take from mine own hands a quantity of my Tincture to carry into the Country for his own use, and that of his family and Friends; Discoursing with me about my Tinctura Caelestis told me, how highly he esteem it, for that he had taken of it from Mr. Powel, Bookseller in Southampton my Correspondent, and that he had been long troubled with the Stone, and used ma●y Medicines in vain, bu● taking of my Tincture, the very first Glass brought from him ●●●●y Stones.  
I lately also received a Letter from Mr. Alexander Kemp, Chirurgeon in Basin Stoke in Hamp-shire, of an Eminent Cure he did with this my Tincture Caelestis, upon man who had been severely afflicted with a swelling in his Privities, large and very painful who continues sound and very well.  
I could add many others but I am confined, and these must at present suffice, to show, that by these powerful and effectual operations, this Celestial TINCTURE dot● comfort, support, and preserve the Principal parts and Members of the Body, as the Head Heart, Stomach Liver, Gall, Spleen, Mesentery, Reins and Bladder, in the just measure o● strength and Vigour, which is of the greatest importance in the World, according t● that of Paracelsus, Conserva membra principalia & mors non facile eveniet, saith he, Preserve the principal Members of the Body, and death makes but slow approaches. But when the are out of order, and cease to perform those Offices, for which God and Nature ordaine● them, the Strength fades, Sickness prevails, and Death obtains the Conquest.  
In that universally lamented Disease the Scurvy, it is a certain and Sovereign Remed● for as the Scurvy, is a disease of the whole Body, known by a dull, heavy, listless, f●● and lazy indisposition to undertake and perform the common actions of Life, that weakness and uneasiness in such as are necessitated to follow business, so, it is also apparent● sharp putrid humours seizing the more remote and solid parts of the Body, causing 〈…〉 ●oose, discoloured, soul and unsavoury Teeth and Brea●h also red, or bluish Spots like flea-bites, in the skin of the Breast, Arms, Thighs, and Legs, sickness of the Stomach, weak digestions, loss of Appetite, Wind, Stretching and Belching, also rise in the skin like the stinging of Nettles, and also frequent movable pains, in the Back, Sides, Head, Shoulders, Arms, Legs, and Joints, as are sometimes suspected to be a worse Disease, and very often passeth for the Gout, and degenerateth oftentimes into the Dropsy, and hath at other times the Jaundice joined with it, with many other violent symptoms hard to be described, being infinitely various, according to the different constitutions of such as suffer under them. All which are caused by a general defection and revolt of the principal Members before mentioned, from their several offices and functions, whereby an abundance of evil humours are ●eaped up, to the annoying and disordering the whole frame and complexion of the Body. Now for the certain Cure, and total rooting out of this woeful Distemper, there is not a more ready and exquisite Medicine than this Celestial Tincture, to be used as hereafter mentioned. Moreover this GREAT TINCTURE is incomparably prevalent against the many Diseases of Women, which out of a respect to that tender Sex I forbear to describe at large: Therefore in short, It is a present h●lp in the many infirmities of the Womb, cleansing it, from those impure humours which slow into it, causing Fits of the Mother, Vapours which disturb the Head, Heart, Stomach and Vitals, causing great Stopping, Swelling, Strangulation, Ulcers, Pains, and infinite other dismal effects, throughout the whole Body; by reason of its affinity with all the, Noble parts. In all which it gives a seasonable relief, and preserves Nature in her due Course. It restores to the Pale Virgin, a fresh and pleasant Countenance; and to such as want their Feminine sickness, it brings That, with all the case and satisfaction that can be expected, and so prevents a multitude of Evils which usually attend those defects.  
It is exceeding available in Worms in Children and in the Rickets it affords present help.  
In times of Contagion it is an high preservative and keeps off all Infection, which will be of great use to such as by full eating and drinking, and other easy and luxuriant ways of living, are apt to get Surfeits and Fevers, and will probably be more obnoxious to such Diseases in this ensuing year, which according to the Perdictions of our Astronomers, (taken from those dreadful Configurations of the Heaven, and Malevolent Aspects of the superior Planets) is like to produce many Mortal Sicknesses; And happy are they who have such Means at hand, and prudence to consider a threatening mischief and prevent it.  
Lastly, In all these Sicknesses, Diseases, Distempers, Infirmities, Indispositions o● the whole, or any of the parts and Members of the Body herein mentioned, this Generous Medicine, my TINCTURA CAELISTIS is prepared to answer all the indications and intentions, of their Cure, being of Virtue equivalent to their Exigences accommodated to such their Extremes of weakness; and to preserve and support Nature Vigorous, sound, strong, and in a lasting state of Health.  

Directions for the Use of the TINCTURA CAELESTIS.  
It remains now, that I only give some Directions for the use of this Celestial Tincture, in which I shall be very brief, for a Public Medicine should in no wise adm●● 〈◊〉 difficulties, to perplex or puzzle the Senses or Memory of ●he Reader with tedious