LICENCED,  
Apr. 1. 1676. Ro. L'Estrange.   

THE ADMIRABLE VIRTUES, And Wondered EFFECTS OF THE True and Genuine Tincture OF CORAL, In PHYSIC; Grounded upon Reason, established by Experience, and confirmed by Authentical Authors in all Ages.  
Never found out plainly till now.  
By Theophilus Garencieres, Doctor in Physic, Colleg. Lond.  
Io suon Medico non di Parole ma d'Effecto.  Cardan. 
London, Printed by W. R. for Samuel Sprint at the Sign of the Bell in Little Britain. 1676.   


Collegium Sancti Johannis Evangelistae in Academia Cantabrigiensi    

To the Honourable Sr WALTER LONG, BARONET.  
SIR,  
I Hope not to incur your blame, when I prefix your Name to this small Treatise. The Matter is new, though long sought after; the scope is the public good, and my private aim is to show my gratitude for so many obligations you have been pleased to lay upon me, besides my hopes, that the design of the Subject may perhaps be approved by experiment, and the smallness of the Volume pass among those things that are not illusory. And to say truth, under whose Wings could I have sheltered it better than yours? Whose Affability and Candour is open to the greatest Strangers, and particularly myself, with your never enough to be commended, generous Hospitality.  
But my intention here, being not to make your Panegyric, I supersede and spare your Modesty, it being sufficient to me, if the Author and the Work can deserve your Protection, and the favourable Looks of your worthy Brother, Master Robert Long, and so engage me to remain the rest of my days  
Your most humble and affectionate Servant Garencieres.   

Ad Authorem De Extracta CORALII Tinctura Dodecastichon.  
A Multis quaesita diu Tinctura Rubentis  
Coralii, nobis ecce reperta patet.  
Quod veluti rigidum durescit in aêre marmor,  
Cardiacus mirâ jam datur arte Liquor.  
Lethiferi poto coguntur cedere morbi;  
Aufugiunt pestis dira, maligna febris.  
Cedit & infantum convulsio; foemina Laesae  
Matricis rabido laeta dolore vacat.  
Ista sub ingenti crescentia pharmaca ponto,  
Hippocratis dicant munera digna manu.  
Filum Parca secet; non te vixisse pigebit:  
Si tua tam rarum tempora finit opus.  
Petrus Cottereau.   

THE CONTENTS OF THE BOOK.  
CHap. 1. Of Coral, and of the divers kinds thereof.  
Chap. 2. Of the Nature, Faculties, and Virtues of Coral.  
Chap. 3. Of the Tincture of Coral, and what is Tincture.  
Chap. 4. Why in the Curing of Diseases, we choose rather to make use of the Tincture of Coral, than of the whole Body in substance, however prepared.  
Chap. 5. How the Tincture of Coral worketh upon Diseases.  
Chap. 6. Of the Virtues of the Tincture of Coral, in the Curing of all Malignant Fevers.  
Chap. 7. Of the dangerous and poisonous quality and use of Blistering Plasters, and that they aught to be exterminated out of the Family of Remedies.  
Chap. 8. Of the Virtues of the Tincture of Coral, in all Fevers and Agues.  
Chap. 9 How the Tincture of Coral worketh upon all those other Diseases, we have said it was fit for.  
Chap. 10. How and in what Vehicles the Tincture of Coral is to be administered.   

CHAP. I  
Of Coral, and of the divers kinds thereof.  
COral is a Shrub, growing in the bottom of the Sea, which becometh Stony when exposed to the Air.  
Sic & Coralium, quo primum contigit auras  
Tempore, durescit; mollis fuit herba sub undis.  Ovid. 4 Metamor. 
Therefore is it called by the Greeks 〈◊〉 〈◊〉 〈◊〉 〈◊〉 〈◊〉 and 〈◊〉 〈◊〉 〈◊〉 〈◊〉 〈◊〉, that is, The Stony Tree, in Latin Coralium.  
There is divers sorts of it according to their several colours; for there is a Read, a White, a Black, a Green, a Yellowish, of an Ash-colour and of mixed colours. The Read, which is called the Male, is preferred above all the rest, and is the subject of this our Treatise. Anselmus de Booth, Physician to the Emperor Rodolphus the Second, affirmeth, To have seen in the said Emperor's Cabinet, Branches of Coral of several colours upon the same Body; so that the Body of it was Coral and Stony, and the Branches Ligneous and Woody, which is not improbable to me; for I have seen in the North of Ireland a Lake called Lake Neaugh, wherein, if a piece of Wood that groweth thereabout be planted, that part which is in the Ground shall be turned into Iron, that which is in the Water into Stone, and what is above Water shall remain Wood But let us come to Coral again, whose generation is not much unlike; for when that Juice that is in it, called by the Latins, Succus Lapidescens, runneth through the Body of the Vegetable, it altereth it, and turneth it into a stony substance. Whence we may g●ess, That Coral, under Water, is not altogether soft and flexible, though it groweth stony, when exposed to the Air; which cannot be wondered at, seeing there be many Stones, both in France and England, which being newly digged out of the Ground, are in a manner as soft as Cheese: But having been a while exposed to the Air, grow to a considerable hardness, the Sun and the Air having exhausted the waterish part of them. Now whether Coral groweth out of the Petrifying Juice, or being engendered as other Plants, is at last altered by the said Petrifying Juice, is a question. For my part, I believe that it doth not grow without that Petrifying Juice, not more than the Sea-fan, called Corallina, the Alga, and other Herbs which grow in the Sea, and that it doth not petrify till it dieth: By dying, I mean, that when by the ordinary course of Nature, or by the violent action of the Stony Juice, penetrating the inmost parts, the Plant is petrified. Now it is certain, that Nature maketh use sometimes of the Petrifying Juice for the producing of the Plant; for it hath been observed by many, that Coral hath grown out of the pieces and fragments of Earthen Pots. And in the Island called Tobacco, near Africa, which is half swallowed up by the Sea, much Coral is found, having its Roots in pieces of Earthen Pots. Now the reason why Coral should petrify, and other Plants not, is because of its peculiar disposition: As also, because naturally there is a Petrifying Juice in it, which forceth the Plant to receive a stony form; besides the peculiar disposition, and preparation of it to receive such a form. No reason can be given for its colour, not more than for that of a Rose; for it cannot be referred to the first or second qualities, not more than the sight of the eye. God hath been pleased to adorn things with such colours, and hath so inserted them into their Seeds, as their Archaeus can produce none other; Coral sometimes groweth to the height of a man before it be ripe and turned Read, it seemeth of several colours; for as many Plants as I have seen that were not wholly petrified, were all of a Dusky, Green, or such colour as we see in other Trees; and those only begun to be Read, that had nothing woody in them, as we see that in Pears and Apples, the Read colour is a sign of their ripeness and maturity. When Coral is newly taken out of the Sea, many impure things stick to it outwardly, which being taken of, the true colour showeth itself. There are several sorts of Coral in respect of their matter, for some is soft, other hard, some solid, some hollow, some rough, some polished, some porous.  
When Coral is taken out of the Sea, it is for the most part rough, and than is made smooth and polished by the Artists: There is a Black Coral found in Gallicia, a Province of Spain, and such another sort of course one, called Savalia, is brought from Mauritany, having the inside woody, and the outside horny, and stony, of a Black, Yellow, and Green colour. There is also a sort of White Coral found in Catalonia, and called by the Spaniards Polo: This hath no Bark, and groweth in the bottom of the Sea, and not upon Rocks, as the Read doth. The best Coral is now found upon the Coasts of Tunis and Tripoli. Theophrastus' in his Book 〈◊〉 〈◊〉 〈◊〉 〈◊〉 〈◊〉 reckoneth Coral among the precious Stones; and Orpheus in his Book 〈◊〉 〈◊〉 〈◊〉 〈◊〉 〈◊〉 speaketh very much of Coral. Before I end this Chapter, and speak of the Virtues of Coral, I will here, in favour of the curious, clear a doubt, and show an error concerning its Nature that hath reigned a great while (because Pliny writeth, that Coral while it is in the Sea, is as soft as Wax, but assoon as it cometh to the Air it groweth hard) by an History, taken out of. Beguinus own words in his Tyrocinium Chymicum.  
Upon this Controversy, john Baptist of Nicole, Squire of the City of Marseilles, chief Commander for the Fishing of Coral in the Kingdom of Tunis, hath assured me, That in the year One thousand five hundred eighty four, being upon the Sea of Biserty, belonging to the said Tunis, where the said Fishing of Coral was, and being curious to know the Nature of Coral, and how it groweth in the bottom of the Sea, caused a young Man to dive into the Sea a hundred fathom deep, being tied to a rope of a sufficient length, with a weight of five and twenty pounds in each hand, to go to the bottom, charging him to bring some Coral from the bottom, and to observe, whether it was hard or soft. Being come above Water, he brought a Branch of Coral in each hand, affirming, That it was as hard in the bottom of the Sea, as out of it, and that being about eight or nine fathoms near the bottom, he felt an excessive cold. The same Nicole not contented therewith, as the Nets were coming up, and before they could be in the Air, cast himself into the Sea about one fathom deep, and took some Coral sticking to the Nets, which he found as hard as when it is in the Air. The same hath been confirmed to be me by the Lord of La Piotier, a Gentleman of Lion, who within these two years returned from the said Fishing of Coral. Besides this, the said Squire Nicole assured me, that in the Spring when the Coral is plucked up, in the breaking of it, there issueth out a liquor like unto Milk, which falling upon any Stone, Wood, Iron, or some other matter, produceth Coral; and that he had seen in the Cabinet of the great Duke at Pisa, the Skull of a dead Man, upon which was grown in the Sea, a great Branch of Coral; and an Anchor taken out of the Sea, upon which were several Branches of Coral, produced by the Juice of Coral that fell upon it.  
Here we must rectify a kind of seeming contradiction, which is, when we have cited Ovid and Mathiolus, and said, That Coral was soft under Water, and grew hard when it came into the Air; and in another place, That by the experiment of Squire Nicole, it was found to be hard under Water; therefore understand this only to be Secundum magis & minus, as of those Stones which we have said to be as soft as Cheese in the Earth, and than to harden in the Air when digged up, for the Reasons before alleged. For though Coral may be hard in the bottom of the Sea, yet it is nothing so hard as when it hath been exposed a while to the Air; and so we perceive it to be in all kind of Trees which dry and harden to the Air, when once weaned and separated from their natural sap or moisture, and growing place.   

CHAP. II.  
Of the Nature, Faculties, and virtues of Coral.  
ACcording to the Famous Dioscorides and his Learned Commentator Mathiolus, Coral in his manifest qualities is moderately astringent and cooling; but his specific qualities, are so many and wondered, that I should show myself too prolix and tedious, if I would treat of them one by one. Therefore I shall content myself to lay down the chiefest, and to back them with the Authority of several Learned and Famous Men, and shall begin with Anselmus de Booth, Physician to the Emperor Rodolphus the Second, in his Book De Gemmis & Lapidibus, wherein he saith, That the tincture of Coral stoppeth the immoderate Courses of Women, both Read and White; the Running of the Reinss; the Spitting of Blood; and cureth all Bloody Fluxes, and Gripe of the Guts; expelleth all kind of Gravel and Stones, and consumeth the over-growing of the Spleen. I can testify of myself (saith he) that being extremely sick of a Pestilential Fever, and fainting every moment, and having been without sleep four days and four nights; insomuch, that all those about me, despaired of my life, by taking in a Spoon six drops of the said Tincture, with the decoction of Violets, upon an instant, and as it were miraculously, I was cured. For assoon as I had taken two Spoonfuls of the said Tincture, I felt my Vital Spirits so refreshed, and my entrails so comforted by the gratefulness and efficacy of the said Remedy; that as if the Light had expelled Darkness, I found manifestly the strength of the disease abated, and fell into a critical Sweat (of which before there was no sign.) So that Nature did thrust to the skin abundance of Purple Spots, which presently being obliterated and carried away by the Sweat, in a little time I recovered my former health. That Tincture (saith he) hath the faculty to bring the Body to a right temper by a certain Celestial Power, and eradicateth all Diseases out of the Internal Parts, by reason of the Analogy it hath with the Vital Spirits, and the natural heat which it augmenteth and strenghtneth, and therefore overcometh easily the contrary Diseases. It cureth the Falling Sickness in few weeks, though one hath had it from his youth. It is commended above all against the immoderate Fluxes of Women, either White or Read; for it doth stay them so, that the Women cannot fall into any inconveniency by it. It doth also stop all Fluxes of the Belly, and of the Blood from whatsoever part it floweth. It also stoppeth the old Run of the Reinss. It is given in the Plague with admirable success: Likewise in the Flux and Small Pox, chief when they do not come out kindly. It is also excellent against Melancholy and the Tympany. It appeaseth the Pains of the Eyes, stayeth the Rheum, and taketh away the Spots that grow in the Eyes.  
In a word, Coral strengtheneth the Heart, and therefore is a sovereign Remedy against the Plague, and all venomous, contagious, and malignant Diseases. It is a certain Antidote in the Plague time, if one taketh of the said Tincture in a Morning fasting, the quantity of half a drachm. It hath the same power against the poison of Vitriol, which is analogal to that of Fevers and Agues, causing Gripe in the Stomach, and the Guts, Vomiting, Looseness, thickness and blackness of the Tongue, Short-breath, and other dangerous Symptoms, which is confirmed by Forestus, Lib. 30. Observat. Med. Observatione 7. in Scholio. Arnaldus Villanovanus relateth, That if ten grains of the Tincture of Coral be given to a Child newly born, mixed with some of the Mother's Milk, before the Child hath taken any other Meat or Drink, that the said Child shall never be troubled with the Falling-Sickness; which is also affirmed by Camillus Leonardus, Lib. 2. Speculi Lapidum, Litera, c. Thus far Anselmus de Booth.  
Our second Author shall be Crollius, the Prince of Chemists, who saith this. As Coral doth wonderfully grow, so the Secrets that are in it, are altogether admirable, and its Faculties beyond expression. The virtue of its Tincture is such, that it is able to cleanse and renew the Blood in such sort, as to cure all Diseases that comes from the corruption thereof, and to restore health, strength, and alacrity. It stoppeth all immoderate Fluxes in Women, being taken in Plantain Water; as also all Lasks and Fluxes of the Belly, as Bloody Fluxes, Dysenteries, Diarrhoeas, taken in the decoction of the Roots of Tormentil; all Hemorrhages, Spitting of Blood, and Haemorrhoides, taken in Plantain Water; cleanseth and reneweth the Blood, taken in the Water of Fumitory or Cichory. Resisteth Putrefaction, strengtheneth the Heart, and the Vital Spirits, and preserveth them from Poison, in Water of borage or bugloss. Comforeth and strengtheneth the Stomach, and the Natural heat in Mint or Penniroyal Water. Removeth all obstructions, chief from the Lungs, Liver, and Kidneys, in Water of Sorrel, Grass, Little Centaury, Spleenwort, Liverwort. Dissolveth congealed Blood in Water of Chervil or Daisy. It cureth absolutely the Fits of the Mother, and the immoderate Fluxes of Women, in the Water of Motherwort, Balm, Penniroyal. It cureth the Dropsy, Convulsion, Palsy, Falling-Sickness, in Cinnamon Water, continuing for a while. It expelleth the Stone and Gravel in Saxifrage Water, or that of Restharrow. The dose is from six grains or ten, to a scruple or two, according to the age of the Patient, and the greatness of the distemper. It cureth Ulcers being applied to them, or mixed with Plasters proper for them.  
The third Author shall be Joannes Petrus Faber, a famous Physician of Monpelier, who in his Book called Myrothecium Spagiricum, in the Chapter of Coral, speaketh thus. The virtues and force of this Secret for the mund●●ying, and purifying the Blood in all the Body, is such as it may be given in all sick●●●●●● and diseases, which proceed from the 〈◊〉 of the Blood, in so much that it 〈◊〉 excellent in the Leprosy. It stayeth 〈◊〉 〈◊〉 Fluxes in Women being taken in Plantain Water; as also all kinds of Loosenesses, and other Bloody Fluxes against Nature. It comforteth and strengtheneth the Heart wonderfully, as also the Stomach. Restoreth the Natural heat, by reason of its radical moisture, which is almost equal to ours. It dissolveth all Congealed Blood and Scorbutical Concretions, therefore also most profitable to those that have the Stone and Gravel, being drunk in the Water of Restharrow. It is wonderfully efficacious in all venomous Ulcers, and others, if it be mixed with some proper Balsam, because it mundifieth the Blood, and procureth Cicatrization.  
The fourth Author shall be our worthy Countryman, Roger Bacon, who in his Learned Treatise De Retardanda Senectute, commendeth Coral in these words. That Remedy which lieth in the bottom of the Sea, is of a wondered virtue against the infirmities of old age, as experience teacheth us. It is hot and dry in the second degree, as Isaac affirmeth. It doth corroborated the Stomach, the Senses, and all the internal parts.  
The fifth Author shall be the most renowned Fernelius, who speaking of Coral, saith thus; Coral being cold and dry in the second degree, by his Astringent quality strengtheneth the Stomach, and efficaciously stoppeth all Bloody Fluxes, preserveth the strength of the Heart, and fenceth it against all malignant and pestilent Diseases. Being taken inwardly, it stayeth the monthly Courses of Women, and strengtheneth the Conception. It hindereth Excrescences of Flesh, filleth up the cavity of Ulcers, and weareth out the Scars in the Eyes. It cooleth the heat of Choler, and stayeth the eruptions of it, whether upward or downward. It strengtheneth the substance of the Liver, let it never be so lose.  
I could in confirmation of the Premises, bring the authority of all the best Physicians in all Ages that have made mention of Coral, but that I am an Enemy to Prolixity and Repetitions. These will serve to satisfy any reasonable person, or else nothing william.  
In a word, the Virtues of Coral are so great and wondered, that many grave and authentical Authors did not stick to say, That it was an Amulet or Charm against Fearfulness, Bewitchings, Sorceries, Poisons, Falling-Sickness, Assaults of the Devil, Lightnings, Sea-storms, and other dangers whatsoever. Therefore in ancient time it was dedicated to Jupiter and Apollo. But of these last qualities, let every one believe as much as he thinketh fitting: Certain it is, by the testimony of Pliny, and others, that anciently it was among the Indians almost of an equal value with Pearls of the same bigness. It is also certain, that Read Coral, if worn by a Man, hath, and preserveth its colour better than that which is worn by a Woman; perhaps, because the heat of a Man is greater than that of a Woman; and the vapours that exhale out of his Body are purer.  
Moreover, it is an undoubted truth, That Read Coral will grow pale, bluish, and maculated with several spots▪ when it is worn by one that is nigh death, or dangerously sick, and will foretell Diseases by the changing of its colour. This I found true by a sad experience of my own; for having once a Girl about Twelve Months old that wore a Bracelet of Coral, she fell into a Pestilential Fever: So that when I came home and spied the Coral quite altered, I began presently to despair of her recovery, which I would not have done, if I had known than the Tincture of Coral, as I do now. She lived but two days in that case. After her death I would have taken the Bracelet from her, and tried whether I could have brought it to its former colour again; but the Mother would never suffer it, but would have it buried with her, jest the sight of it should bring her into remembrance of her loss, and so deprived me of so just a curiosity. Here by the By, Let us consider what affliction it is to Parents to see their young Children sick, without any Remedy, and not able to express their own grievances, whereas now a spoonful of this Tincture, which is pleasant to the taste, and can be no ways hurtful, may preserve them alive to the honour and glory of God, and the satisfaction, and joy of their Parents and Relations.   

CHAP. III.  
Of the Tincture of Coral; and what is Tincture.  
TIncture is an Extract of the Colours adhering to mixed Bodies, and of the formal qualities thereof. Whence cometh it, that Tinctures are sometimes called Oils, sometimes Spirits, and sometimes Quintessence. In the Extraction of Tinctures, the Chemical Artists do chief labour, that they may separate the formal Virtue of the mixed Bodies, in which lieth the faculty of curing Diseases from its proper Matter or Feculent Body, which is unprofitable, Terrestrial or Waterish; for they draw by Extraction and Means of a determinated Menstruum (for the same Menstruum is not fit to draw all kinds of Tinctures) the Tincture or Essence of it, which is the most secret and internal substance that Nature had enclosed and concealed in the entrails of it, to preserve it from all external injuries and accidents. And after that, they draw or abstract the Menstruum from it; and the Tincture or Essence remaineth in the bottom of the Vessel, in the consistence of Honey or Pap, and than it is properly called Extract. But if it be in a Liquid form joined with its Menstruum, and representing the colour out of which it is drawn, than it is properly called Tincture. Therefore observe that by the word Tincture, the Chemists understand the colours sticking to the Essence of the mixed Bodies, and to the formal qualities drawn out of them.  
Here we must make an exact distinction, between a Dissolution and an Extraction of the Tincture; for in a true Tincture we extract only the formal Virtue of the subject, the mass and lump of the Body remaining whole; but in a dissolution, the whole compound is reduced into minute parts. Hence cometh it, that the dose of the Tincture is small, but that of the dissolution must be in a greater quantity, because it is not so efficacious.  
Observe also, That there is no true Tincture, but that which remaineth of the same colour as the mixed Body was, after the Menstruum is extracted from it. If by this rule many Tinctures be examined, it will be easily known that they are no true Tinctures, but that their colour proceedeth from the mixture of the Menstruum with the Body dissolved.  
For example, Let any body take of the Vulgar Tinctures of Coral, if you exhale or distil the Menstruum from them, it will go away pure and clear, and that which remaineth shall not be Read, but shall look either like Lime or Salt; whereas, if it were a true Tincture, and a Read Substance extracted from the Body, it should remain so, though the Menstruum were abstracted from it. But that Tinctures are not always true, but vary according to their Menstruums, is evident in that several colours may be extracted out of one and the same thing by several Menstruums. For example, if you put upon Silver calcined with Mercury sublimate, the Spirit of Salt; you shall have a Green colour like an Emerald, but if you put upon it the Spirit of Urine impregnated with the Salt of Urine, it will be of a Blue colour. These contradictions did persuade once Crollius, an excellent Chemist, when he wrote his Book called Basilica Chymica, That the true Tincture of Coral was impossible to be had, or at lest, that it was not his fortune ever to see any. But we shall convince him sufficiently of the contrary, and as many as shall be of his opinion.  
Here I cannot wonder enough at many Chemists and Physicians of good note, who through ignorance, or by hear-say, for the obtaining the Tincture of Coral, advice to calcine it, that the Tincture may be drawn out of it, without considering that in the Calcination the fire burneth and consumeth the Tincture, and that Calcination is good for nothing but to Extract the Salt of it, which also hath several Faculties in Physic of which we shall speak in its proper place. For Calcination is the Reduction of a mixed Body into a Calx or Lime made by fire, which depriveth the said mixed Body of the humour or moisture that united the parts together.  
Now it is time to come to the true Tincture of Coral. Take therefore (for an experiment) half an ounce of the best Coral in Powder, put it in a Viol of about half a pint, pour upon it six ounces of our Menstruum, and stop the Viol close with a Cork, you shall perceive, that within four hours the said Menstruum will be coloured Read, than pour it out, and put new upon the same Coral, and so do, so often till you shall see the Coral white in the bottom of the Glass, than abstract the Menstruum in Balneo, in the bottom shall remain the true Tincture of Coral as Read as Blood, and the Body shall remain in the Viol as white as Snow: Edulcorate, that is, Wash the said Tincture from its Menstruum with some Cordial Water, which you shall afterwards Abstract from the Tincture in Balneo, till it be almost dry, than shalt thou have the true Tincture of Coral, most efficacious for the aforementioned Diseases, being given in some appropriated Vehiculum, and fit for the distemper. The dose is from ten drops to twenty, or thirty, in two ounces of an appropriated Liquor.  
When you have Extracted the Tincture of Coral, do not slight or throw away the Body of Coral which remaineth in the Viol, for out of it may, by Chemical Art, be Extracted the Salt of Coral; which in all respects emulateth and cometh very near the Tincture, except in the curing of malignant and pestilential Diseases.  
I am here much surprised at the contradictory opinion of Philibert Guibert, a famous Physician of Paris, who in several places of his Book, called The Charitable Physician, having highly commended the use of Venice Treacle against the Plague, and other ven●mous Diseases, according to the doctrine of the best Physicians, doth at last in his Treatise of the Plague, exclaim against it as against an infamous Remedy, contrary to the authority of the best Physicians, and the constant experience of all Ages, as I have showed in my Treatise of the last Plague Anno 1665. and instead of it, substituteth two Antidotes of his own, which are something Comical. The first is, The use of good Wine; the second is that which he calleth Electuarium de tribus Adverbiis. Cito, long, tarde. That is, to be gone quickly out of the infected place, to go far from it, and to come back as late as one can, according to this old Distich.  
Haec tria tabificam pellunt Adverbia Pestem,  
Mox, long, tarde, cede, recede, redi.  
But as we do not deny that Wine is a noble Aliment, and a great Cordial, so do we think it too weak alone to cure the Plague, as is seen in many places where people drink nothing but Wine, and that of the best: Not more than his Antidote of the three Adverbs, many having met with the Plague in the Country, which they might have avoided, if they had stayed in the City, as I did all the while: For I do undertake (with the Grace of God) to cure the fiercest Plague with Venice Treacle, and my Tincture of Coral. Add to this, that many people are not able to go out of Town, either want of means or relations, or being encumbered with a numerous Family.  
Before we finish this Chapter, it will be worth the curiosity of the Reader to know how to Extract the Salt of Coral, which we have said to emulate the Virtues of the Tincture, except in the curing of the Plague, and malignant Fevers.  
Take therefore that white Body of Coral which remaineth in the Viol, after the Extraction of the Tincture, wash it very well with fair water, dry it gently upon a soft fire, and than pour upon it by degrees Vinegar, that hath been distilled three times, as much as will cover it four Fingers above, than digest and dissolve that together, and after the solution, Abstract the Vinegar till the Coral be dry; than wash the Coral with distilled water, to take away the acrimony of the Vinegar; after that, evaporate the Water till there remaineth a Salt as white as Snow, and free from all acrimony, which must be kept in a Glass close stopped.  
It's virtues are most excellent, for it purifieth the Blood in all the Body, which it restoreth to its former strength. It stoppeth all Fluxes of the Womb, of the Belly, and of the Haemorrhoides. It strengtheneth the Heart, and the Stomach; it openeth all the obstructions of the internal parts; it dissolveth congealed Blood. It is most excellent in the Dropsy, Palsy, Convulsion, the Stone, Fits of the Mother. Crollius is of the same opinion; for he saith, That it purifieth the Blood, and cureth in a short time all Diseases that proceed from the corruption of it, if it be taken in Cichory or Fumitory Water. To stop all excessive Fluxes and loss of Blood, as well by Dysenteries and Haemorrhoides, and such like; as Hepatical Fluxes, Lienterical, Menstrual, Spermatical, Bleeding at the Nose, Spitting of Blood, being taken in Plantain Water, or such like; to resist putrefaction, to strengthen the Brains, the Stomach, the Natural heat, and the Vital Spirits, and to preserve the Heart against all poison; to remove all obstructions from the noble parts, to wit, The Lungs, the Liver, and the Kidneys; to dissolve congealed Blood, and to cure the most stubborn Fits of the Mother, and superfluities of the Monthly Courses, being taken in the Water of Motherwort, Balm, or Pennyroyal. See Crollius in Basilica Chymica, and Anselmus de Booth, cap. 154. Lib. 3. de Gemmis.  
In the Dropsy, Palsy, Falling-Sickness, and Convulsion, this Salt is taken with admirable success in Cinnamon Water; and for the Stone, in the Water of Restharrow. It may also be put in Lozenges, and be taken in stead of common Salt in a boiled Egg, or in Broth, or in White Wine.   

CHAP. IU.  
Why in the Curing of Diseases, we choose rather to make use of the Tincture of Coral, than of the whole Body in Substance however prepared.  
Disease's never come upon mankind, but by a Segregation and Heterogeneity of humours; for while the Crasis or Temperament of the Humours, remaineth whole, Nature constantly performeth her Functions, the Spirits play their part, and the oeconomy of the Body remaineth entire; but assoon as the Humours begin to separate themselves, and to jar one against another, the Spirits are scattered, the Humours putrify; and if there be any malignity in the Air, it introduceth itself immediately into that Chaos.  
Now these Indications teach Physicians, first, to expel the malignity as the most pressing; secondly, to settle the Spirits; thirdly, to unite again the Humours. Now the malignity being aerial, cannot be expelled, but by formal Qualities, neither can the Spirits be settled but by the same; which both being done, the third, which is the union of the Humours, will of necessity follow; for the Cause being removed, the Effect ensueth. These things cannot easily be done by a Body in Substance, (suppose Coral in Powder) for in that Body the three Principles of Nature, to wit, Salt, Sulphur, and Mercury, remain united together, and so adhere one to another; that although nature may digest them, yet will they not separate themselves to do the Body any determinate good, but will either undigested or digested, go all along and keep company together; whereas, when they are separated one from the other, they work determinately by the help of a proper Vehiculum, upon the disease aimed at. For though all the parts (for example of Coral) be friendly to an Human Body, yet are they more friendly one to another, and will not separate themselves to do a Body good, but will rather stick close and perish together, to the illusion of the Physician, and the delusion of the Patient. The second Reason is, That when the Remedy is given in Substance, Nature is put to the work and task of digesting it, and in the mean time the disease (chief if it be aerial) getteth footing, the strength declineth, and so many times the Scales weigh down; whereas, if it be given separate (suppose the Tincture of Coral) Nature presently layeth hold on it, cheereth up the heart with it, who presently as the Sun of the Microcosm sendeth it, by way of irradiation, to the part affected, and so relieveth the Patient.  
Another inconveniency ariseth from giving Remedies in Substance, which is, that when the thinnest part of the Remedy, is dissolved in the Body, the thickest, which the Latins call Faere or Crassamentum, remains in the way, and many times causeth stubborn obstructions, and other accidents, whose Causes being unknown to the Physician, because unsuspected, produce many times several accidents worse than the Disease that was intended at first to be cured. This is to be daily observed in those that use gross and f; aeculent Means, and by the Reason we have alleged before, fall into stoppages and obstructions, and consequently into divers Diseases hard to be cured.  
From this Reason it is, that Spirits and Essences separated and sublimated, work more powerfully and efficaciously, than when they are wrapped and involved in their whole Bodies, 〈◊〉 〈◊〉 whom they cannot easily extricate themselves, and show forth their power and virtue, as you may observe in Spirit of Wine well rectified, one spoonful of which shall work more effect than a quart of the common one, out of which it is extracted. The same is of Vinegar, which, if it be pure and good, shall in the quantity of a spoonful, in Sauces, Salads, or other condiments, do more effect than a quart of the common one, and with lesle charge and more gratefulness; because its efficacy and virtue before was dulled, allayed, and made inefficacious by the faeces, phlegm, and other impurities that adhered to it. Upon this Reason, the Remedies that are to be administered to Human Bodies, are to be pure, rectified and exalted: If you well consider the effect you expect from them, and the dignity of the subject with whom you have to do. Therefore the best Chemists in all Ages have endeavoured and laboured to make their Remedies as pure and defecated as possibly they could, that the effect aimed at, might follow, and the Human Body's excellency should not be violated, as it is not, when in the preparation of the Remedies, the pure is separated from the impure, the useful from the unprofitable, the spiritual from the corporeal, and the cordial from the poison: And thus they do not lie heavy upon the Stomach, they beget no impurities, 'cause no new obstructions, but immediately fight against the Diseases, and overcome them. Thus, Beer well settled is wholesomer than new; thus Wine separated from its Tartar, is better for the taste, and for the health, than when it is newly extracted from the Grape; thus the Meats we eat, being separated by Nature from their Excrements, after many light concoctions and separations of Excrements in the Liver, and in the Veins, are at last made fit for the nourishment of the parts. Thus, Cinnamon Water shall sooner and more efficaciously comfort the Heart, than Cinnamon itself in Substance; thus, a few drops of Oil of Aniseed shall work more effectually than many Seeds, and thus of the rest. Whereby you may see that Remedies well prepared and purified, are extraordinary efficacious for the cure of the worse Diseases; as the Falling-sickness, the Convulsion, the Dropsy, the quartan Ague, the Gout, and other Diseases commonly deemed incurable; and that with all safety diligence, and alacrity, imitating Nature in this, which doth not sand to the parts for their nourishment the Meats as they are raw and whole, but altereth them in the Stomach, digesteth and destroyeth them, and in the Liver separateth the purest from the Excrements.  
Now concerning the penetration of the Virtue of the Tincture of Coral, to the remotest parts, for the Curing of those desperate Diseases, we have mentioned, as Falling-sickness, Convulsion, Gout, Pox, Bleeding out of any part of the Body, etc. Consider how the Milk of a Nurse that hath taken Rheubarb, is able to purge a Suckling-Infant, etc.   

How the Tincture of Coral worketh upon Diseases.  
BUt that we may make this obvious to the meanest capacities, we will lay here open the most secret Foundations of Physic, to wit, The Actinobolism of Natural things, which is not where else so clearly to be seen as in Medicinal ones; and this is twofold, either to life or to death. Which that you may understand, you must observe, That as all things were created for Man's sake, even so there was given to every one a particular virtue by which Man might be preserved: For he that intendeth the End, intendeth also the Means to attain it, as are the Virtues of Natural things. Seeing than that there is no Member in an Human Body, but hath its proper and peculiar infirmities, the most High hath provided Remedies against all them; seeing also that there be Members hidden and concealed in the most retired places of the Body, where there was no access for Herbs and Plants to come to. He hath given them like as it were Beams of Light, spreading themselves round like those of the Sun, which passing through all the Body, do by their Actinobolism or Irradiation, penetrate to that Member which is correspondent to them, and hath need of their Faculties and Virtues. Hence cometh, that the Remedies having spread the Beams of their Virtues, go directly to that Member which is analogal and correspondent with them, and strengthen and comfort it. Thus all Cordials by their Actinobolism, do not meddle with the Liver, Brains, or Spleen; but with the Heart.  
The Hepatical Remedies by their Actinobolism, do not comfort the Kidneys or the Lungs, but the Liver: Thus, the Diuretics meddle not with the Liver, Heart, or Brains, but with the emulgent Veins, and the Bladder. Thus, the Actinobolism of the Catharticks and Diaphoreticks, gather together into the entrails, all the Choler lurking in the Body, and from thence carry it away as a superfluous and noxious thing.  
Hence it is manifest, by what Reason the compounded Medicines, endowed with divers qualities, work upon the Body unconfusedly, and are no hindrance one to another, not more than the Sun's Beams are among themselves, as it is demonstrable in Mathematics. For seeing that the Specific Virtues of each Medicines which enter into the Composition, remain in it after the loss of their first qualities, when they are received in the Stomach, as in a Natural place, every kind, without mixing one with another, and confounding their Beams, tends to that part to which it is affected, and hath correspondency with, and with their Actinobolism, do wonderfully strengthen and comfort it. Whence cometh, that all the Members being comforted, the Natural heat must also of necessity be strengthened; and the more it is, the lesle power will the Disease have; insomuch, that we may imagine in Physic as many Centres of Virtues as there be Individuals that compound it; and if there be many Cordials mixed together, they all shall cast their Beams upon the Heart: Those Herbs that have relation to the Lungs, shall work that way, and the Hepatical ones, shall all tend to comfort the Liver. And thus by the Aggregation of so many Virtues, the Body must of necessity prevail against the Disease: So contrariwise, that Antipathetical Actinobolism which proceedeth from poisons, and poisonous things, assoon as it is got down into the Stomach, doth first attack the Heart, as the fortress of the Body. Thus the Mineral Poisons, as, Arsenic, Orpine, Ochra, and the Poisons of Serpents, by their radiation, infect the next Blood, and that the next, and so consequently, till it hath reached to the Heart. Whence if it be not expelled by the Antactinobolism of some counterpoison it bringeth destruction to the party: Besides that, every Member hath its peculiar Poisons; for some do not attack the Heart immediately, but the Lungs. As, that Zoophyte, called Pulmo Marinus, which being eaten, ulcerateth the Lungs, and bringeth the party into a slow Consumption. The Sardonian Smallage, as also that Insect called Tarantola, invading the S●ats of the Spirits, and the Arteries and Muscles, provoketh a Man to laughing and dancing. The biting of the Serpent called Dypsas, as soon as it beginneth to diffuse, doth by its Radiation bring the Liver into Putrefraction. The biting of a Mad-Dog giveth to a Man the Dog's manners; for he continually barketh, biteth, and feareth Water. The biting of a Mad-Cat, imparteth the Cat's manners. Skenkius relateth of a Maid that had eaten of a Cat's Brains, and did perfectly imitate a Cat's manners, expressing its voice, and hunting after Mice with her crooked Fingers and Nails. The Poison of an Asp being an enemy to the Nerves, doth by its Radiation 'cause a sudden lack of Sense in all the Limbs which it corrupteth. The biting of the Serpent (called for that reason Haemorrhois) by its Radiation turneth all the Humours of the Body into Blood, as Gesnerus witnesseth, Lib. 5. Hist. Anim. Which is confirmed by Lucretius in his Ninth Book, by these excellent Verses.  
Impressit dentes Haemorrhois aspera Tullo,  
Magnanimo juveni miratorique Catonis:  
Vtque solet pariter totis se effundere venis  
Corycii pressura croci: Sic omnia membra  
Emisere simul rutilum pro sanguine virus.  
Sanguis erant lachrymae: Quaecumque foraminanovit  
Humour, ab iis largus manat cruor: Ora redundant  
Et patulae nares, sudor rubet, omnia plenis,  
Membra fluunt venis: Totum est pro vulnere corpus.  
We may see by these and several other Experiments, which I omit for brevity's sake, that the several Members and Parts of the Body have their several Substances, which do not work by their proper Poisons, but by the Diffusion of their Radiant Virtues; which cannot be remedied, but by the Radiation of contrary Substances which destroy those venomous qualities, even as the shadows and darknesses cannot be destroyed but by the Radiation of Light. From all these things it is evident, that there is nothing in Nature without that virtue of Radiation, inserted by the Author of Nature, for those ends best known to himself, and in imitation of the Light, insomuch, that the Judicious Reader, by this Doctrine of Actinobolisms, and that of Magnetisms, may as with two Wings soar to the highest knowledge of Natural things. He that will be further satisfied in examples of that nature, let him read Skenkius de Venenis.  
To these must be added what we have said before, to wit, That the Specific Virtues of each Medicine that enters into a composition, remain in it after the loss of their first qualities which may be proved by this Experiment.  
Take Nettles, dry them, and burn them to ashes, make Leeses of those ashes; expose the Leeses in the night to the Air, till it be covered with an Icy thin Skin, and you shall see in that Skin the perfect figure of a Nettle, with the stretching of its fibers and jagged Leaves, as if it were a Natural one; and if you look upon it with a Magnifying Glass, you shall perceive with admiration all the ●igure of the Nettle, grown out of small and almost infinite number of small Cellules. Th' same will hap in any other Plant, to show that no Seed can be so exactly mixed with other things, but it will retain and affect still its own Nature. All this that we have said, tendeth to show how Coral bringeth to pass all those wondered Virtues we have attributed to it. Those that shall desire to be better satisfied in this Doctrine of Actinobolism and Radiation, let them seriously meditate the Plastical Virtue of all Seeds, in which, being seated in the abstrusest parts of the Body, doth without any tools or noise, produce a work so wondered in variety and comeliness of Parts, and that, out of a rough and inform matter, in which there is no distinction of parts, nor variety that may be observed by the Senses. For we see that in the Seed, without any appearance lieth and lurketh the whole Tree, with the Roots, the Body, the Boughs, the Leaves, and the Fruits. Out of one Corn of Wheat, proceedeth the Root, the Stalk, the Ear, and the Corn. In an Egg, which is the Seed of Birds, lurketh the whole Bird, with all, and every one of its Limbs, and all the differences of its colours. In the Seed lieth the Body of the Animals with all its Limbs, the Heart, the Brains, the Lungs, the Liver, the Spleen, the Stomach, the Kidneys, the Bladder, the Nerves, Tendons, Muscles, Veins, Arteries, etc. Every one of which hath its proper and certain figure, its colour, and proprieties. Who severeth so many various things hidden in an Homogeneal Body, who separateth an uniform Matter into Bones, Humours, Flesh, Gristles? etc. None other certainly, but that Plastical Virtue which the Almighty hath inserted into all things that were to be propagated by Generation. This Virtue giveth to every Limb its due situation, colour, figure, proportion, and quality: By its workmanship the Body is hollowed into so many Pipes, Channels, Passages, and Meanders. Therefore, we suppose, that the same Plastical Virtue, is diffused in all the parts of the Seed: So that it is all in all, and all in every part of the Seed.  
The reason is, That the Productions are sometimes but one, and sometimes many; and that the Production that cometh from one part of the Seed, is no lesle perfect than that which cometh from the whole: And finally, that there is no confusion nor inordination of parts, which of necessity should hap, if it were not uniform with the Subject; for if one part of the Seed were taken away, one part of the Production should also be wanting. And thus should hap a Confusion in the Figure by the transposition of the parts: And although the Seed, in order to the Senses, seem to have no distinct and heterogeneal parts; nevertheless, being considered in itself, it hath: Seeing that it is not a single, but a Body compounded of many; for that part of the Plastic Virtue which frameth the Brains, shall not frame the Heart or the Liver; and that part which hath framed the Bones, shall not stretch the Membranes, or dispose the Guts into a winding compass. The only difficulty is, Why that Plastic Virtue, which is so confusedly mixed, yet, worketh without confusion, and disposeth of all things with an admirable order, and as the Greeks call it 〈◊〉 〈◊〉 〈◊〉 〈◊〉 〈◊〉.  
But this concerning not our Subject at present, we pass it over, being contented to have stirred up the curious Reader to the Meditation and Study of the Magnetisms and Actinobolisms, in which he shall found matter enough to satisfy himself in the process of Nature, and in the admiration and love of the Creator. But this digression hath passed a little already the bounds of our Subject, let us go back from whence we came.  
We conclude than, That the Tincture of Coral being separated from the Body of it; the pure from the impure; the formal from the material; the Celestial from the Terrestrial, it worketh by its A●●inobolism or Radiation, and its Magnetism; by which it is Analogal to the Heart, the Fountain of Life, those wondered Effects we have made mention of, we will descend to some particular Instances.   

CHAP. VI  
Of the Virtues of the Tincture of Coral, in the Curing of all Malignant and Pestilential Fevers.  
WE give this instance first, as the most considerable, and of greatest concernment. These Fevers under the notion and name of a Cold, having destroyed so many of late, that a Body cannot without grief, and a certain horror, read the increase of the Bill of Mortality upon this particular point, while the Patients flatter themselves that it is nothing but a Cold; and the Physicians, either by ignorance, wilfulness, or mutual Envy, prescribe Bleeding, Purging, Blistering, and such other dangerous and preposterous means; which though they may sometimes be used in other Fevers, yet in this are they Mortal.  
As first for Bleeding, it hath always been condemned by the most judicious in Malignant and Pestilential Diseases, by reason that it weakeneth Nature, by exhausting the Blood wherein the Life consisteth, by diminishing the Spirits which are the tie of the Soul with the Body, and by suffering the venomous quality to rage's the more by substracting that sweet and Natural Juice, which was rather to be encouraged for the taming and allaying of it.  
Purging is neither to be admitted, unless there be an extraordinary fullness of Humours, it being sufficient to keep the Body soluble; as also, because in those Fevers there is commonly a perturbation of Humours, which Purging cannot segregate, till they be perfectly concocted, and appear so by the Urines, and the slacking of the bad Symptoms. Concocta medicari oportet non cruda, saith Hypocrates.  
As little significant as these, is the new way they go about by Blistering; for whereas this Pestilential Fever hath its seat in the Spirits, what communion is there between their Malignity and Blisters, which do not reach beyond the skin, set the whole frame of Nature in torture and anguish, and cut the troth of the Patient before the Wounds can be cicratrized? This practice seeming only invented to beget Apothecaries practise and Physicians somewhat to say, when they are at their wit's end.  
Now nothing remaineth to overcome so powerful an enemy but Cordials, so called, because, without doing any violence to Nature, or weakening her strength, they directly go to the Heart, cheer it up, fight against the malignity; and as a Light disperseth darkness, so do these, any thing that is enemy to Man's life. Which being done, that wholesome temper, in which consisteth Life and Health, taketh place again, and the Patient is restored to his former state.  
Under that name of Cordials, every one almost obtrudeth what his own fancy and imagination thinketh, or hath heard to be so, though it be but a simple Distilled Water, coloured with some Syrup; and thus trifle away the most precious thing of the World, which is time (as C●esiphon saith) while the malignity gets footing, and never ceaseth till it hath destroyed the Patient.  
Now, as we do not deny that there is abundance of those Remedies called Cordials, in Nature; so we deny that it is every one's Talon to know them, or the use of them, or the preparation of them. As for example, What good can be expected from the Water of a Plant Distilled in a Mettallick Furnace, having been first irrorated or steeped in common Water, that the greater quantity may be drawn, as it is now commonly practised. Besides the inconveniency of the Metallick quality of the Limbeck which communicateth itself to the Water, as it is evidently seen, and have often tried myself: For having occasion several times to prescribe Mineral Waters, as that of Epsom, Tunbridge, etc. to several Patients, and among them, to my own Daughter. It fell out, that the Water which was brought from the Wells in Bottles, did agreed very well with them, and wrought effectually without any violence; but when, by the want of that, I was forced to make use of that which they fell in Town, and keep in Leaden Cisterns, I found a contrary effect; for it wrought so untowardly, that it frighted me every time; which I could attribute to nothing else, but to the poisonous quality of the Lead, of which the Cisterns were made, and in which the Waters were kept. By this we see what a necessary thing it is, in such cases, and many others, That a Physician should be his own Apothecary; and this I speak merely for the interest of the truth, being not ignorant how many interessed persons will contradict it.  
Having set down all these Notions, it is also requisite we should set down the use of our Tincture of Coral; therefore assoon as one falleth into that Malignant or Pestilential Fever, which is known chief by the smallness, quickness, and intermittency of the Pulse, let him go to Bed in a warm Room, and being well covered to sweated, let him drink one dose of our Tincture of Coral, sweeting after, as long as he is a able; and let him follow exactly the method we have set down in our Book of the last great Plague, Anno 1665. The particulars of which concerning this, we shall repeat here, because the Book is hard to be had, there having been three Impressions dispersed in six week's time, and none to be had at present, that I know: Therefore I shall repeat to this purpose, only the XXX. XXXI. XXXII. XXXIII. XXXIV. XXXV. XXXVI. Aphorisms mutatis mutandis.  


XXX.  
Assoon as any one findeth himself stricken with any of these Symptoms, to wit, a Headache, Vomiting, Faintness, Looseness, and a small quick and intermitting Pulse, without any prejacent or evident cause, let him presently repair to a clean and warm Room, and let a light fire of Wood be kindled in the Chimney, to consume and destroy all the infectious vapours that proceed both from the Air, and the infected party. Let the Patient be presently put into a warm Bed himself, wrapped in a Sheet and Blanket, having first put of his Shirt, that when he cometh to be dried, you may not be put to the trouble of pulling of his wet Shirt, than give him one dose of our Tincture of Coral, and covering him with clothes very warm all over, leaving only his respiration free, and putting a warm Brick to the Soles of his Feet, and another to his Knees; let him sweated as long as he is able, or at lest, for the space of three or four hours, and be not afraid he should faint, if he hath breath enough.   

XXXI.  
If it should hap, as it doth commonly to those that are first taken with a vomiting, that the Patient should cast up the Cordial, you must give him another dose; and if he should cast up this also, give him a third, and so continued still till he keepeth it once, for he will never cast it up afterwards; and though he should, yet by having taken it so often, some of the qualities of it will remain behind, that will work their effect.   

XXXII.  
Children that cannot or will not take the Remedy, must be compelled to it by pouring it into their Throat with an Instrument, called by the Greeks 〈◊〉 〈◊〉 〈◊〉 〈◊〉 〈◊〉, which is a kind of Spoon with a cover, having a spout to put into the Mouth, and so to pour it down.   

XXXIII.  
The Patient having sweated three or four hours, the more the better, you must give him a little more breath, and began to take of the clothes by degrees; and when you have dried him very well with warm clothes (which all this while must hung by the fire with his Shirt) than pull away the wet Sheet and Blanket from under him, than give him his Shirt, and after that, dry his Head, and take heed, by all means, that any cold Air should come into the Room. After you have dried his Head sufficiently, and that the party beginneth to be cool, give him to drink leisurely, two ounces of our Cordial Water, described in the said Book of the Plague, which is of an admirable virtue in this case, and also in Faintnesses, Surfeittings, and Poisons, This will refresh him so speedily and wonderfully, that he will presently forget the tiresomness of his sweeting.   

XXXIV.  
When he is quite cold, give him to eat any thing he hath a mind to; so that it be of good Juice, and easy digestion: Let his drink be strong Beer, lukewarm, or some Generous Claret Wine; for, as we have said before, this Fever differeth from all others. And whereas in others we subtract Meat, and strong Drink, as much as we can, we must in this allow them, it being only a malignant quality, in which, good Meat and Drink cannot hurt, but rather alloy it, as also because the Patient would not be able to sweated twice a day in this manner (which of necessity he must do, if he will save his life) unless his strength be repaired with good nutriment.   

XXXV.  
This course of Sweeting twice a day, must be continued for four days together or five at the most, in which space of time, all the Malignity and Pestilential Poison will expire; and, if this be carefully done, and attended, there is no Malignant or Pestilential Fever so stubborn of any kind whatsoever, but must yield.   

XXXVI.  
Although the danger be over in four days, yet will it not be amiss to make use still of Cordials now and than; for it is not only necessary to dive away the Pestilential Poyon, but also to strengthen the noble parts, upon which it may have made an impression, the malignity of a thing being not only in the Cause, but also in the parts to whom the cause did adhere.    
Thus much have I transcribed out of my Book of the Plague, for the ease and conveniency of the Reader, and for the advancing the use of so noble a Remedy, as the Tincture of Coral.  
Now seeing that this Tincture is to be administered with our admirable Water against the Plague, and Malignant Fevers, and that the Substance of both is more formal than material, not lasting long in the Body; therefore the dose is to be renewed every day, allowing about three hours of Interval between every dose, besides one dose in the night, if the Patient awakes. If this be carefully done, there is no Malignant Disease but may be cured.  
But as a Gardener that will carefully bring up a Plant, taketh care to weed it often, jest it should be choked or want nourishment. So that I may show the beauty of this Remedy, I must extirpate several Weeds that have crept in of late into the Family of Remedies, to the delusion of the Patients, and the irrision of ignorant Physicians.   

CHAP. VII.  
Of the dangerous and poisonous quality and use of Blistering Plasters, and that they aught to be exterminated out of the Number and Family of Remedies.  
MAny times when a Physician is at his wit's end, and hath nothing to say more concerning the Disease in hand, he prescribeth Blistering, not knowing nor distinguishing whether it will be fitting or not. And there is some policy in that too; for besides the obligation, he layeth upon h●s Friend the Apothecary, himself is not without hope of benefit, and of being sent for, the more often whiles the wounds are green; but what good this can do, or which way, chief in a Malignant Fever, you must not ask, for himself cannot tell, but only, that it is the common practice of the Town. Which, if it be a satisfactory answer, let every body judge. If this abuse had been harmless, I would have passed over it, as I do over many others that I know, and do only range among the Vulgar Errors. But seeing it tendeth to the destruction of mankind, as I have seen by many sad and woeful experiences, and shall prove by many grave and Authentical Authors, I should sin against my Conscience, Reason, Knowledge, and Experience, if I did not lay open the cheat thereof, in favour of a gallant Nation, among which I live and am so humanely protected.  
Be it known therefore, that there is a Remedy now practised in Physic called by the Greeks 〈◊〉 〈◊〉 〈◊〉 〈◊〉 〈◊〉 from the Verb 〈◊〉 〈◊〉 〈◊〉 〈◊〉 〈◊〉, which in Latin signifieth Attraho, in English, to draw or attract, which was invented by the Ancients, chief to comfort the weakness of those parts which come by cold, or too much moisture, whence it is evident, that all those Remedies are exceeding hot, dry, and sharp. Of these sorts are Mustardseed, Thapsia, Goat's Dung, Cresses-Seed, Eliampanes Roots, the Sea Onion, Pigeons Dung, Mice Dung, Lice-Bean, Cantharideses, and such like; of which, at present the Modern Physicians, and namely the Dispensatory of London, have framed a Plaster for that purpose, called Emplastrum Epispasticon, of which, here is the description.  

Emplastrum Epispasticum.  
R. Sinapeas.  
Eupborbii.  
Piperis longi ana drachmam unam semis:  
Staphisagriae.  
Pyrethri, ana drachmas duas.  
Gummi Ammoniaci.  
Galbani.  
Bdellii.  
Sagapeni, ana drachmas tres.  
Cantharidum integrarum drachmas quinque.  
Picis navalis.  
Resinae.  
Cerae citrinae ana drachmas sex.  
Terebinthinae, quantum sufficit, fiat Emplastrum usui reponendum.   
Now, as I will not deny but that Plaster may be useful in some cases, if it be judiciously applied; so I affirm, that it is of a dangerous efficacy, if it be misapplied, and chief upon tender Bodies, extenuated by Sickness, Fasting, Watching, and Pains; the Reason is, That the Cantharideses or Spanish Flies, which are the Basis of it, are a most deadly Poison, and a particular enemy to the Bladder and Genital Parts, which is so much the more prevalent, in that some Apothecaries of their own accord to make the Plaster of a more quick working, have augmented the dose of the Cantharideses. So that when this Plaster is applied to one sick of a Malignant Fever, and already extenuated with the disease of Fasting and Watching, he hath good luck if he escape with life. Those that are for it, may chance to urge their own experience, against which I shall oppose mine, which is of forty years standing; but because neither they or I should be believed, as being Partial, I shall cite here some memorable observations made by several learned, honest, and famous Authors, to clear this point, which is of so great a consequence.  
I shall not speak here of the dangers and cruel Symptoms that follow the taking of Cantharideses inwardly, because they are so generally known, that no body can be ignorant thereof, but those that are altogether ignorant of Physic, I shall only mention the pernicious effects, and sad consequences they 'cause, being applied outwardly. The first Observation shall be taken out of Guilielmus Fabricius Hildanus, a late Author, and excellent Physician and Chirurgeon in Switzerland, in his Ninety and eighth Observation.  
A certain Gentleman of the Town of Villeneuve, by the Lake of Geneva, having a cold Tumour in one of his Knees, caused by a cold, and tough Humour, did ask a Barber's advice, who without taking notice of the Antecedent Cause, went about to cure him only with Topical Remedies; therefore he applied first Cupping Glasses, after that a Cautery on the side of the Kneepan, thinking to empty the Matter that was gathered. When these did not succeed, he applied a Pultess made with Leaven and Cantharideses, and did exulcerate all the Knee, than followed an excessive pain about the Knee, restlessness, a Fever, and several other fearful Symptoms; among which, was a grievous pain of the Reinss, and of all the Belly, and presently after such a heat in his Urine, that he could not make one drop (for it came only drop by drop, and that Bloody) without the greatest torture imaginable. The Pultess being removed, he was something the better, because it had drawn the most subtle part of the Humour: Which when the Barber saw, he applied again the same Pultess of Cantharideses, upon which all the said Symptoms became worse than before, and chief the heat of Urine, which the Patiented feeling would admit not more of the said Pultess, but dismissed his Barber, and after came to me to Lausanna▪ where having prepared first his Body with opening Apozemes, I purged him several times with the aggregative Pills, and those of Her modacts; and after that, gave him the decoction of Guaiacum, Sassafrass, and China, causing him to sweated gently, that the Matter about the Knee might melt and evaporate, after that I applied this Pultess of Vigo.  


℞. Farinae Fabarum.  
Farinae hordei, an. ℥ iv.  
Furfuris bene triturati M. ij.  
Stercoris Caprini triturati lb. ss.  
Meliloti an. m. 1. cum Lixivio & Sapa sufficienti de omnibus fiat Emplastrum solidum addendo olei Camomelini & Anethini ana ℥ ij, applicetur calide bis in die.   When he had used this Pultess a whole month together, he recovered his health. You shall found the like example in Joh. Langius, Lib. 1. Epist. 47.  
The third Observation shall be taken out of Baccius, in Prolegomenis Venenorum & Antidotorum, where he saith, We found by Experience, that Cantharideses being mixed in Blistering Plasters, and applied, do most violently corrode the Stomach and the Belly; but above all, to be by its property a peculiar enemy to the Bladder, and to tear it in pieces with its Bloody Urine, and so to kill the Patients. For we have observed many times, that when Cantharideses have been applied to the Head in a Lethargy, and to the Brawns of the Arms and Legs; they have caused an extreme pain, with an inflammation and difficulty of Bloody Urine, and so have killed the Patients. Which danger deserves a serious consideration.  
The fourth Observation is out of Brassavolus, Comm. ad Aphor. 17. Lib. 2. who saith, That one Vincentinus Grema, a famous Chirurgeon in his time, took once a Medicine, the Powders of which had been stamped in a Mortar, where Cantharideses, had been stamped before: Whereupon, though he did not actually eat any Cantharideses, yet was he excoriated from the Mouth to the Fundament, and could not get his health again in lesle than eighteen Month's space; yet were there no Cantharideses in the case, but a kind of quality proceeding from them that stuck about the Mortar.  
The fifth Observation is out of Bartholomeus Montagnana, a famous Physician of Italy, who relateth, That one Francis Brac, a Citizen of Milan, having applied some Cantharideses to his Knee, did avoid by Urine above Five pounds of Blood; and that the same did hap to one who applied them to his great Toe, to take away the roughness and unevenness of his Nails. Langius, Tom. 1. Epist. 47.  
But what is more incredible than this is, That a certain Chirurgeon of Milan, made twice Bloody water, for carrying in his Pocket a Vesicatory made of Cantharideses. Thus affirmeth, Joan. Michael Paschalius, Method. Curand. Morb. cap. 44.  
The sixth Observation is of a certain Man who carrying by chance Cantharideses in his Pocket, as the fashion is of some Surgeons, did make Bloody Urine; and complaining to me of it, I bid him he should not meddle with them, not not so much as to touch them, or carry them in his Pocket. Such another accident, I was told by Helidaeus de Paduinis, a famous Physician of Bolonia, with whom I used to visit sick people, when I was at Bolonia. The most famous Physician Adolphus Occo in his Observations.  
The seventh Observation is of a Noble Woman who having her Face full of read, burning, and ugly Pimples, was so deformed therewith, that every Body avoided her as a Leper, and the Magistrates were ready to sequester her from the common society of Mankind. She came to Paris, where having called for two Doctors of Physic, to wit, Hollerius and Grealmus, and two Surgeons Mr. Cabal, and myself, she inquired with great care and diligence, if there was no remedy against such a deformity. Having considered diligently the disease, we unanimously concluded that it was no Leprosy, but that it was fitting that a Vesicatory made of Cantharideses should be applied all the Face over, three or four hours after her Bladder began to ache, and to burn vehemently, and the Neck of the Womb, to swell with gripe, a continual vomiting, and making of water, a raving carriage of all her Limbs, and a Burning Fever. I called for the Physicians again presently; the conclusion was, That we should give her much Milk to drink, and inject some in the Guts by the Fundament, and into the Womb and Bladder by the Vrethra; that she should go into a lukewarm Bath, wherein should have been boiled Linseeds, the Roots and Leaves of Mallows and Marsh-Mallows, of Violets, Hemlock, Pursleine, and Lettuce; and so to continued, from time to time, till the pain was quite ceased. That the Reinss and Genital Parts should be anointed with Vnguentum Rosatum and Populeon, dissolved and mixed with Oxycrat. By these means all the Symptoms vanished away, in the mean time the Face was full of Blisters, which being broke, a great deal of Matter issued out, and the deformity was cured, insomuch, that a little while after she was married, and had many Children. Ambrose Paraeus, Lib. 5. cap. 17.  
For my own part I can certify, that my youngest Daughter Elizabeth, being about thirteen or fourteen years old, and very subject to sore eyes; after I had purged her, and let her blood in the foot, I applied a Vesicatory of Cantharideses, at the bottom of her neck, thinking to make a diversion of the Humour, but within three or four hour after she fell stark lame of her right hip, so that I was forced presently to remove the Vesicatory; and for all that, the lameness continued three or four weeks after. By what I have said, it is apparent what a dangerous thing Cantharideses is, not only inwardly given, in which case they are a deadly poison, but also outwardly applied; as is seen by the several Observations I have made here, and many more may be taken out of Forestus, Cabrolius, etc.  
I could also here relate some fatal Observations of my own, and of which, I have been a sad eye-witness; but that I do not love to renew the grief of the living Relations, nor to insult on the miscarriage of Physicians, knowing that we are all faulty, and that against death we have no power but forgetfulness.  
From these things we may perceive the truth of what Mathiolus saith upon the Sixth Book of Dioscorides, where he hath these words.  
Cantharideses are hurtful chief to the Bladder, and to all the parts that serve for the evacuation of Urine, not only being taken inwardly, but also being applied outwardly where there is occasion to Blister, chief when they are mixed with large Poultices, and are applied to places near the Bladder, to wit, the Hips, the Privy Parts, the Kidneys, or the Stones. Thus far Mathiolus.  
Therefore if any Body will make use of them, it is necessary he should do it prudently and circumspectly, chief let the young Physicians take heed, lest in prescribing Remedies which admit of Cantharideses, they do not err in quantity; for because Cantharideses are so light, that fifty of them weigh scarce one drachm, the Error is easy to be committed. Nay, the most ingenuous of the Apothecaries have confessed to me, that in the Dispensation of their Emplastrum Epispasticon, they double the dose of Cantharideses to make it of a quicker working. Who shall be so bold after this, to make use of so pernicious a Remedy, and chief in Malignant Fevers, where the Poison is inward, the Vitals dejected, the Natural strength abated, and no good can be alleged to come out of this Remedy? All the excuse being, that it is a common practice about the Town, that is, a common and a pernicious Vulgar Error. Away than with those dangerous things, more pestilent many times than the disease itself; and let us turn our practice to a safer and nobler way, that is, our Tincture of Coral, which without danger, but rather with a great deal of pleasure, performeth in Malignant Fevers, and other diseases, we have or shall mention, the three so much required Indications, for the relief of the Patient, and the honour of the Physician, to wit, Cito, tuto, jucunde.   

CHAP. VIII.  
Of the Virtue of the Tincture of Coral, in all Fevers and Agues.  
I Have ranged these two Diseases under one Head, because they are of the same Nature, except that Fevers are continual, and Agues intermittent, but both to be cured the same way.  
I am not here to express the Nature of all Fevers, which belongeth to the general knowledge of Physic, and would swell this little Treatise into a Volume, but to touch as much of them as will serve our own intention, and to show how the Tincture of Coral is, and may be a Sovereign Remedy for them: Therefore leaving asides their several Definitions, Divisions, and Controversies, we shall only mark the chief Grounds of their Nature, and the Analogy that is between it and their Remedy, to wit, The Tincture of Coral.  
First than let it be established, that a Fever is a hot intempery proceeding from a Preternatural heat kindled in the Heart; and from thence dispersed into all the Body, by the means of the Veins and Arteries, and hurting the Natural Actions. The chief Indication for the curing of them, is to take away that Preternatural heat, and to reduce the Body into its former temper, as we see, that all things after they have left their boiling and fermenting, and are cooled, become purer than they were before. Wherein it is to be observed, that the Natural heat, and the Preternatural, differ chief in this, That the Natural heat is a Substance, and the Preternatural only a Quality. The ignorance of this difference is the cause, that so many miscarry in Fevers; for when Physicians go about that Preternatural heat (suppose by Bleeding) they altogether quench the Natural one, which by all means aught to be preserved, and so hasten the Dissolution of the Patient, by taking away the Basis, upon which, Life is founded: For what need is it, if one desireth to take away the Preternatural heat, and so to cure a Fever, that he should also take with it the Natural one, in which consisteth a Man's life; for the Preternatural heat being once removed, the other remaineth free for the exercising harmonically the Functions of the Body. The only easy, and sure way therefore to cure Fevers, is to extinguish the Preternatural heat, without doing prejudice to the Natural one, but rather comforting and strengthening it.  
Now I affirm, that this cannot be done safely but by separating the Preternatural heat from the Natural; and so expelling the Preternatural, while the Natural remaineth in liberty, to perform the Functions of Nature; which being helped by noble and harmless Remedies, will quickly and safely disburden herself of what is noxious and spurious, as we have showed before in the example of Anselmus de Booth: And this by an Universal Evacuation through the Pores, because the disease is universally dispersed through the whole Body; which by this means is not only lightened of its burden, but comforted and strengthened by the virtue and efficacy of this noble Remedy.  
It is also to be observed, That the Natural heat is Celestial, as flowing from the Sun, Sol & homo generant hominem, and the Preternatural, is Elementary; and therefore easily separable from the other: But some Body will object perhaps, that besides the Preternatural heat which makes a Fever, there may be mixed with it a Latent Malignity, and ask what shall become of it? I answer, That the Preternatural heat, and the Malignity go away together in the Evacuation; for the way way through the Pores, being free and open, and this Remedy being one of the most powerful Cordials in the World, driveth away from the Heart, that is, from the Centre to the Circumference, whatsoever is an Enemy to the Human Body, and that with a great deal of ease and security.  
Now concerning those Fevers called Intermittent, or as the vulgar termeth them, Agues, the Method and Remedy is the same, except that the Salt of Coral must be mixed with the Tincture, because these Agues have their foundation in a toughter matter than the Fevers, to wit, in the Humours; as the Tertian in Choler, the Quotidian in Phlegm, the Quartan in Melancholy, wherein they harbour, as in their proper Ferment, which they will hardly forsake till it be destroyed. Now the Tincture of Coral alone, being too Formal and Spiritual to destroy and disperse those earthly drosses, we in this case join with it the Salt, which cutteth and inciseth the toughness of the matter and density, and prepareth it to expulsion, when the Tincture cometh to radiate upon it.  
I have thus a little enlarged myself upon this subject of Fevers, because there is no disease more vulgar and frequent; for seeing that most of other diseases do not seize upon Human Bodies equally, but are more or lesle familiar to some Ages, Regions, and Constitutions of Bodies than others; there is no Age, Region, and Constitution of Body, that can promise' to itself a freedom from Fever; and, as it is a frequent disease, so is it most dangerous, and not without cause: For it occupieth the Storehouse of the Natural and Vivifying heat, wasteth and destroyeth it, and unless that Fiery and Preternatural heat be timely prevented, it scattereth and devoureth the Natural one; which being the Treasure of Life, Death is presently at the door, insomuch, that most people die of that disease; or rather, as Galen saith, Nemo sine febre moritur, No Body dies without a Fever; which is the reason, that the Ancient Romans having a mind to court it, and to tender it propitious unto themselves, did build it a Temple and Worshipped it superstitiously as a Goddess; as Plinius affirmeth, Lib. 2. cap. 24. August. de Civit. Dei, Lib. 2. cap. 14. And Val. Max. Lib. 2. cap. 5.   

CHAP. IX.  
How the Tincture of Coral worketh upon all those other Diseases, we have said it was fit for.  
WE have here and there mentioned several Diseases; in which we affirm the Tincture of Coral to be a most Sovereign Remedy; and that not only out of our own experience, but out of the Authority of famous and learned Men in all Ages, as 

Dioscorides.  
Mathiolus.  
Anselmus de Booth.  
Oswaldus Crollius.  
Joannes Petrus Faber.  
Arnoldus Villanovanus.  
Forrestus.  
Fernelius.  
Cardanus.  
Rogerius Baco.    
And as many others as have written of the Nature and Virtues of Coral, who agreed all in one, and by that means have made it an undeniable truth. It will not be amiss now by way of Recapitulation to mention all those Diseases again, and to illustrate as much as in us lieth, the way and manner how the Tincture of Coral worketh upon them.  

The Diseases against which the Tincture of Coral is a Sovereign Remedy.  
The Plague.  
All sorts of Fevers.  
All sorts of Agues.  
Flux, Small Pox, Measles.  
All immoderate Fluxes in Women, whether Read or White.  
All Bloody Fluxes, Gripe, and Lasks.  
Spitting of Blood, and the Piles.  
Fits of the Mother.  
Dropsies.  
Convulsion.  
Palsy.  
Falling Sickness.  
The Stone and Gravel.  
Ulcers.  
Pleurisy.  
Barrenness in Women.  
Running of the Reinss.  
Intemperies of the Liver, Spleen, and Kidneys.  
Venereal Diseases.  
Faintings.  
Surfeitings.  
Vomitings.   

Against the Plague.  
It worketh both by its Elementary and Specific qualiys; for while by its excellent temper it bringeth all the Humours into a perfect Crasis, and union, and quelleth all the Jars that are among them; the Formal part of it, in which lies the Specific quality doth by its Actinobolism or Irradiation, expel all the Malignancy and Poison of the Air through the Pores, by casting the Patient into a gentle and moderate sweat, and strengthening the noble Parts.   

Against Fevers and Agues.  
It worketh the same way, and besides it destroyeth and scattereth the Ferment, in which lieth the form of the Fever, and the type of the Ague.   

Against the Flux, Small Pox, and Measles.  
These Diseases being naturally rooted in the Body, as a part and portion of the impurity of the Menstrual Blood, which is the reason that all mankind is liable to it once in its life, sooner or later, and may be called The original s●n of the Body, or as Avicenna calleth it, Morbus Menstrui. This noble Remedy cleanseth all those Impurities by separating the pure from the impure, which it thrusteth away from the Centre to the Circumference through the Pores; and so comforteth the noble Parts.   

Against all immoderate Fluxes in Women.  
It worketh by its Specific quality of corroborating the Liver and Spleen, the Intempery of which is the Antecedent and chief cause of all these disorders.   

Against all Bloody▪ Fluxes, Gripe, and Lasks.  
There being such a sympathy between Human Blood, and the Tincture of Coral, it is not hard to guests, that in this case it worketh by the amity and friendship they have together; by which the Blood is cheered up, and, as it were, courted to remain in its Receptacles and Vessels; by which means, and the strengthening of the Vitals, all the Preternatural symptoms cease.   

Against Spitting of Blood, and the Piles.  
All these kinds of Hemorrhages proceeding from a Vein that is either broken, corroded, or gaping, it is apparent, that no better Remedy can be given than the Tincture of Coral, given in a proper Vehioulum, having manifest Qualities for the healing of the Veins, and Specific ones for the staunching of the Blood; and it is agreed by all Authors.   

Against the Fits of the Mother.  
Seeing that this Disease called by the Latins Vteri Suffocatio, hath more several Causes than can at this time be easily expressed. We shall only say, That the Tincture of Coral being ministered in a proper Vehicle, scattereth all those noxious fumes; and by its Radiation, penetrates as far as to the seat of the distemper, and strengtheneth all the Vitals.   

Against Dropsies.  
It is known to every Body that most Dropsies come by an Intempery of the Liver or Spleen; which is visibly and palpably rectified by this noble Remedy, having first purged and emptied the superfluous Matter.   

Against the Convulsion.  
This Disease being most frequent among Children, and proceeding from the Malignant Vapours of the Body, which vellicate and pluck the Nerves, is cured by the Irradiation and Specific quality of this Remedy.   

Against the Palsy.  
The Palsy being an abolishing of the Motion, and sometime of the Sense, caused by the want of the Animal Spirits, which are necessary for the free motion of the Body, is helped by this Remedy; which openeth obstructions, dilateth the passages, quickeneth the Animal Spirits, and makes them fit for Radiation.   

Against the Falling Sickness.  
The Epilepsy or Falling Sickness, is an often stretching of the Body, or a short Convulsion, by which a Man falleth down on a sudden, without Sense or Motion; so that he neither heareth nor seethe, nor remembreth any thing that is passed in the Fit, when he is out of it. In the agitation they foam at the Mouth, and the Muscles being lose, either the Urine, or Dung, or Seed. cometh out involuntarily. This being caused by a Malignant Vapour which proceedeth from either the Brains, the Stomach, or some particular part of the Body, is cured by the Tincture of Coral, given in Paeony Water, after the necessary Evacuations.   

Against the Stone and Gravel.  
In this distemper we give both the Tincture and the Salt; that while the Tincture comforteth the noble Parts, the Salt by its opening and diuretic faculty may waste and break to pieces whatsoever is of Stone or Gravel.   

Against Ulcers.  
Ulcers being either inward or outward, the inward ones are cured by the taking of the said Tincture in a proper Vehicle; and the outward ones, be they never so malignant, are cured by the outward application of it; for it correcteth all malignity, and cicatrizeth them, even to admiration.   

Against the Pleurisy.  
It hath been a general opinion, that a Pleurisy cannot be cured without Blood-letting▪ but give me leave to tell you, That in my forty years' experience and practice, I have seen more misearry by that way, than saved; unless the Body be extraordinarily Plethorical, and the Pleurisy exceeding violent▪ the reason is, that substracting the Blood, you exhausted the Treasure of Life. So that many times, the Patient cannot last till Suppuration, for want of strength and so drops by the way before he can reach home. Add to this, that the Fever which is an inseparable companion of the Pleurisy, is not so soon extinguished this way as it is scattered into several Particles, by this noble Remedy, while the Fomentations discuss the seat of the distemper, and assuage the pain and other symptoms, and proper Poultices utterly dissipate the Imposthume.   

Against Barrenness in Women.  
There being divers and almost innumerable Causes of Barrenness, we do not pretend here to shoe every foot by the same Last; we know that some of the Causes may belong to Chirurgery, as well as to Physic. The judicious Physician that shall be near at hand, will easily distinguish them, and prescribe Remedies proper for them. We do only pretend that whensoever the Cause shall lie in any intempery of the noble parts, no Remedy shall go beyond this.   

Against the Running of the Reinss.  
The Body being duly purged, and the malignity swept away, our Tincture is a Sovereign Remedy to stop it, by comforting the parts, and to prevent any lachrymation or weakness, which use to follow that distemper, and many times put the Patients to a great deal of impatiency, and the Physician to his nonplus.   

Against Intemperies of the Liver, Spleen, and Kidneys.  
This Tincture being given in a proper Vehicle, will rectify them, as well by its Anatical temper, as by its Actinobolism and Specific qualities.   

Against the Venereal Disease, vulgarly called the Great Pox.  
This Disease having its chief foundation in the Liver, which by the Malignant quality of this distemper, hath lost his Tone, and dispersed the Disease through the whole Body. By the use of this Tincture is brought to its right temper again; and all the malignity of the Disease expelled, by the Alexipharmacal and Specific quality of it.   

Against Faintings.  
Fainting is a sudden failing of the strength, that is, a sudden diminution of the Vital, and consequently of the Animal Actions. The Cause is a sudden want of the Vital Spirits, which by the Virtue of this Tincture, and of our admirable Water mixed together, are on a sudden repaired, and the Patient kept in the Land of the Living, as I have sufficiently proved upon divers persons that are alive to this day.   

Against Surfeitings.  
There are two kinds of Surfeits, one in quantity, the other in quality, but both many times mortal. The Surfeit in quantity is, when one eateth or drinketh more than his appetite desireth, and his strength can bear. The Surfeit in quality is, when one eateth or drinketh never so little of a thing that he hath a prejudice against; both are immediately cured by the Tincture of Coral, mixed with our Cordial Water; not as the former Diseases we have made mention of, either by Specific qualities or Actinobolisms, but by their gratefulness and friendliness to our nature, which when it lieth under the burden of a Surfeit, and findeth the gratefulness of this Remedy it graspeth upon it, and let's fall the Matter of the Surfeit, which being loosed it expelleth by Vomiting, without leaving any Particle of it behind, and so is immediately well, as I have tried many times, even to the admiration of the beholders.   

Against Vomitings.  
This is a pernicious Symptom which is much in reign, when a Patient can retain nothing in his Stomach, but immediately bringeth it up all again, whether Meat, Drink, or Physic. But this Tincture, and its Vehicle are so friendly to Nature, and of so admirable a Virtue, that it will immediately stay the Vomiting; And if there be any Cause of it, will bring it up, or if the Remedy stayeth with the Cause of the Vomiting in the Body, it will certainly conquer and destroy it.   

Many more other Diseases could I mention, in which the Tincture of Coral would effect wondered things. But I think these will be sufficient for any reasonable and ingenuous person: Those that will know more, may advice with the Author, who shall ingenuously tell them if it be fit for their distemper or not, and in what Vehicle it must be taken; advising them seriously, That if they receive no benefit by this Remedy in those Diseases for which it is properly administered, they can hardly expect it from any other. The Author having also a peculiar Talon to judge of Diseases, and the Remedies thereof, by the Inspection of Urines, desireth those that will save charges or lives, afar of, to sand their Water; by the examination of which, they shall receive all reasonable satisfaction: And for these purposes and others, he shall give his constant attendance at his own House, from eight of the clock in the Morning, till eleven; and from three in the Afternoon, till five. The rest of the time, it will be known where he is, and when he will be at home again.  
Those also that shall doubt of the reality and extraction of the said Tincture, may have from him some of his Menstruum, with which he extracteth it, and with that and their own Coral, make the experiment themselves.    

CHAP. X.  
How and in what Vehicles the Tincture of Coral is to be administered.  
THis Tincture being so noble and so precious, and working so powerfully in so little a quantity, is to be used with all circumspection imaginable, that there be no waste in the quantity, nor impediment in the quality. There would be a great waste in the quantity, if it were taken alone, and by itself, considering, That one pound of Coral will scarce yield above one drachm of Tincture; therefore we give it in a little quantity (suppose of about twenty drops) in a proper Vehicle, suppose of two or three ounces; that by its diffusion in it, it may go and enter over all the noble parts of the Body; as you see that a grain of Cochenille will die a thousand times of its weight of Water; and that Saffron will diffuse its Tincture in a prodigious quantity of liquor. There would also be a waste in the quantity, if the Tincture were given alone, and by itself; for the Natural heat would consume it, before it could diffuse its virtue, and radiate through the whole Body. Add also, that a Specific Vehicle will make it work more effectually and determinately upon the part aimed at. There would be also an impediment in the quality, if it were not given in a Vehicle that were unfit, or contrary to the distemper that it is given for; as if of two Horses, the one should draw before, and the other back, they could hardly reach home in a convenient time; or, if it were given amongst Meat, or upon a full Stomach, it is evident, that its virtue should be drowned, and its Radiation hindered: As when a thick cloud is interposed between the Sun, and us. For the illustration of what we have said, it is visible, and in a manner palpable, That if the said Tincture were given against the Plague and Malignant Fevers in Plantain Water, it would hardly work the desired effect, because Plantain Water is cool and astringent; and our intention in this, is to expel the malignity of the Plague and Fevers by a moderate sweat, which cannot be conveniently procured, but by a hot Vehicle, such as is our Cordial Water, or that of Carduus, and such other-like. Contrariwise, if in immoderate Fluxes of Women and Hemorrhages, it be administered in hot Vehicles, and not in cool and Astringent ones, such as Plantain Water is, little good can be expected of it, by reason of the contrariety and disproportion that is between the Agent and the Patient, that is, the Remedy and the Disease. Let it therefore be concluded, That it must be given in a proper Vehicle, that is, such a one, as is proper for the distemper, and will forward the effect of the said Tincture, and hath a peculiar analogy and correspondence with the Disease aimed at. As for example, For the stopping of all immoderate Fluxes in Men and Women, it aught to be given in Plantain Water, or the decoction of the Roots of Tormentil. For the cleansing or renewing of the Blood, in Fumitory or Cichory Water. For strengthening the Heart and the Vital Spirits, in Bugloss, or Borrage Water. For comforting and strengthening the Stomach, in Mint or Penniroyal Water. For removing of obstructions in Sorrel Water, Little Centaury, Spleenwort, Liverwort. For dissolving congealed Blood, in Water of Chervil or Daisy. For the Fits of the Mother, in the Water of Motherwort, Balm, Penniroyal. For the Dropsy, Convulsion, Palsy, Falling-Sickness, in Cinnamon Water, continuing for a while, because those Diseases are stubborn. For the Stone and Gravel, in Saxifrage or Restharrow Water. The dose is from six grains or ten, to a scruple or two, according to the age and strength of the Patient, and the greatness of the distemper: And so it may be said of all the rest of the distempers which it is proper for. Upon which, the Author will give his advice to those that shall desire it; and for that purpose, shall give his constant attendance at his own House, from eight of the clock in the Morning, till eleven; and from three in the Afternoon, till five. The same Author having also a special Talon to judge of Diseases, and the Remedies thereof, by the Inspection of Urines, may be advised with at the said time; therefore those that shall be minded to save the charges of Fees, may at the said time bring or sand their Urine, upon sight whereof, they shall receive all reasonable satisfaction.  
As for the said Tincture of Coral, with the Vehicles proper for it, they are only to be had and ministered by him, to prevent all supposition, falsification, or mistakes, the World, at present, being so full of Envy, Backbiting, and Deceitfulness, that he dares trust no Body with it; but is resolved, as he is the sole Author of it, so to have all the praise of it, and bear all the blame alone, if any be. He also carrieth always some of the said Tincture about him, ready to be administered, whensoever occasion shall require, that no time may be lost, as most commonly it is, in acute and exceeding hasty Diseases. That shall not hinder, but if any Body be satisfied with the Virtues and Effects of the said Tincture, he may have of him what quantity he pleaseth to lie by him, against the time of need; and this he doth to make good his Motto, which also was that of Cardan. Io suon Medico non di parole ma d'effetto.  
From my House in Clarkenwel Close, the Second on the Lefthand. Garencieres.  
FINIS.