Second primary cancer in the brain: A longitudinal case study from childhood into adulthood

Jasmin Rahesh MBA, MS, Shazma Khan BS, Arham Siddiqui MBA, Roy Jacob MD

ABSTRACT

Second cancers occur after the remission of a previous cancer in patients. Due to the increased successful treatment of childhood cancers, these second cancers are more likely to occur for these patients later in life. Risk factors and causes for these second cancers include predisposing genetic factors, exposure to radiation and chemotherapy from initial cancer treatment, and environmental conditions. The most likely reason second cancers occur is multifactorial and involves an interaction between environmental and genetic factors. We present a longitudinal case study following a patient who was treated for an ependymoma at age three and twenty-two years later presenting with symptoms indicative of a second cancer at age 25.

Keywords: Second cancer, childhood cancers, brain cancers, neurosurgery, pediatric cancers


Article citation: Rahesh J, Khan S, Siddiqui A, Jacob R. Second primary cancer in the brain: A longitudinal case study from childhood into adulthood. The Southwest Respiratory and Critical Care Chronicles 2022;10(45):63–66
From: Texas Tech University Health Sciences Center School of Medicine (JR, SK, AS), Amarillo, TX; Department of Radiology (RJ), University Medical Center, Lubbock, TX
Submitted: 6/19/2022
Accepted: 10/8/2022
Conflicts of interest: none
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