Monitoring sedation during mechanical ventilation

Arunee Motes MD

ABSTRACT

Sedative medications have been used in intensive care units (ICU) to minimize discomfort, prevent pain/anxiety, allow invasive procedures, reduce stress, and improve synchrony in mechanically ventilated (MV) patients. However, these drugs can have adverse effects resulting in increased length of ICU/hospital stay, health care costs, morbidity, and mortality. This review summarizes the mechanisms of action, usual doses, side effects, adverse effects, contraindications, and recent studies of sedatives which are frequently used in adult ICUs and the sedation assessment tools for measuring quality and depth of sedation in adult ICU patients.

Keywords: sedations, mechanical ventilation, intensive care unit, sedation assessment tools

Article citation: Motes A. Monitoring sedation during mechanical ventilation. The Southwest Respiratory and Critical Care Chronicles 2022;10(45):19–27
From: Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, Texas
Submitted: 9/27/2022
Accepted: 10/2/2022
Conflicts of interest: none
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