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KINGSTON. ONT. 1897. at the Department of Agiioulture, TO FIFE FOWLER, PROFESSOR OF THK PRINCIPLES AND PRACTICE <>K MKDICINI?, AND DEAN OF THE MEDICAL FACULTY IN QUEEN's UNIVERSITY, KINGSTON, THIS BOOK IS RKHPKCTFDLLY DEDICATED BY THE AUTHOR, IN RECOGNITION OF LIFE LONG SERVICES AS A PIONEER AND STEADFAST LABORER IN THE (JAUSE OF HIGHER ■'- MEDICAL EDUCATION IN CANADA. is PREFACE. During the many years the author has been engaged in teaching in various departments of medicine, it always appeared that much valuable time was lost to the student, and important points missed, in efforts to secure such notes as would furnish him with a knowledge of the teachings of the lecturer. When it is demanded of a teacher to so arrange his lectures that his listeners may secure the required notes, liis efforts are apt to become dry and uninteresting, and often simply a species of dictation. In the opinion of the author, lectures, to be interesting, instructive, and impressive, should assume more the form ' of demonstrations, than set lectures, during which im- portant features might be made plain, knotty questions discussed, obscure points elucidated, and methods for medical and surgical treatment made clear by the aid of blackboard drawings, maps, plates, and morbid specimens, leaving the intervening material for study elsewhere. The large and excellent text books on the market are, as a rule, too cumbersome to carry backwards and for- wards to class, and in order that the student might have a convenient text book for such a purpose, and in which he might note important points dwelt upon, and in order that the lecturer might feel he was free to demonstrate the subject as seemed best, without being confined to set lectures, it occurred to the author to place his extended notes in the form of a text book of such proportions as would not be cumbersome, and yet sufficiently compre- hensive as to fully cover the subject. By such means it is hoped to make class attendance less burdensome or PREFACE. irksoiiK*, the material imparted more instructive, and lessen the time required by students in securing an accurate knowledge of the subject. While imdertaking the task., acknowledged by the author to be a difficult one, it occurred to him that by extending the notes a little further the work might be- come a useful adjunct to the general practitioner, whose busy life prevents him securing on all occasions the time necessary for consulting larger works. For such, however, it is not intended as a work for extended research, but from its methbd of compilation, and from its extensive index, it is hoped that it will serve as a means for ready reference, as well as an index to the many large and excellent works on the subject. With these objects in view, the author has endeavored to place the subject in as plain and simple a manner as possible, prefevring simplicity of expression to the adorn- ment of Iniigup.ge. Each subdivision has been briefly described, doubtful points, or subjects open to discussion, discarded, raid oidy such treatment recommended as has stood the test of experience, believing it better to be armed with a few reliable methods of treatment than surrounded by a wilderness of uncertainty. Iti the method of arranging the various subdivisions, tiio author has followed that adopted by Grarrigue in his excellent work, feeling confident that regional classifica- tion is simpler at least than a pathological one. In the description of diseases, or of surgical methods adopted for their relief, names of individuals have, as far as possible, been avoided, as being often misleading. While expressing his own convictions, the author has endeavored to interweave into the pages of the work the opinions of those who represent the most recent and advanced thought, and of those who have been separated out for distinction in the subjects upon which they have written. PREFACE. Mnrgiunl n^ferences mid foot notoH have been nvoid(>(l. because a knowledge of the source of tlie literature that has been incorporated is of no advantage to the student until he has mastered tlie rudiments of the science, and the practitioner can find in tho large works of reference all the historical or other facts v;hich he may seek. Acknowledgment of valuable information is due to the following sources: — Diseases of Women, Cxarrigue; Medicdl and Surgical GymvcokHjy, Pozzi; Diseases of Women, Thomas and Munde; American Text Book of (rijna'coloyij, Baldy; Clinical Gijna'colocfy, Keating and Coe; A System of Medicine, Allbutt and Playfair, Vol. II; Diseases of Women, Lawson Tait; Matnadof (it yna'colo(jy, H. T. By ford; Manual of Gyna'colotjy, Hart and Barbour, Surgical Diseases of the Ovaries and FalUrpiau Tubes, Bland Sutton; Te.rt Booty of Ahdominal Surgery, Keith; Ahdomiuid Surgery, Greig Smith; Diseases of Women, Skene; Feuiale Felric Organs, Savage; System of Sur- gery, DenniH; American Text Bool\ of Surgery; Practice of Medicine, Osier; American Text Booix of Obstetrics; Surgical Patfiology and Morbid Amdomy, Bowlby ; Electricity in Diseases of Women, Massey ; Aseptic Surgical Teclinique, Hunter Eobb; Manuid of Surgical Asepsis, Carl Beck; Principles of Bacteriology, Abbott. In conclusion, the author wishes to acknowledge his indebtedness to Dr. W, T. Connell for valuable assistance in the preparation of the work, and to E. J. Barker Ponse, proprietor of the British Whig, for the facilities offered, and the generous interest shown by him while the work was passing through the press. 52 Johnston Street, Kingston, Ontario. September, 1897. CONTENTS. PART ONE. PRINCIPLES OF GYNyECOLOGY. CHAPTER I. PAGE. Introduotouy y CHAPTER II. Development of the Female Genitals 12 Wolffian diictB. — Wolffian bodies. — Ovaries. -M uUeiian ducts. —Falloi)ian tubes. — Uterus and vaj^ina.— Urethra. — Vulva. CHAPTER III. Anatomy 16 The pelvis. — Mens > eneris. — Vulva. — Labia inajora. — I^abia minora. — Clitoris. — Vestibule. — Vestibule- vaginal gland'*. — Vulvovaginal glands. — Vagina. — Hymen. — Uterus. — Fallopian tubes. — Ovaries.— Parovarium. — Ortran of Rosenniuller. — Urethra. — Bladder. — Ureters. — Rectum. — Pelvic peritoneum. — Pelvic floor. — Pelvic fascia. — Pelvic diaphragm. — Perineal region. — Perineal fa&cia. — Perineal muscles. — Perineal body. CHAPTER IV. Gyn^colooical Technique 40 Sepsis. — Septic infection. — Principal micro-organisms con- cerned. — Asepsis. — Principles of sterilization. — Sterilization by dry and moi&fc heat. — Fractional sterilization. — Chemical disinfection. — Practical application of surgical asepsis. — Methods for cleansing the hands and field of operation. — Sterilization of instruments and instrument ^rays. — A.septic sutures and ligatures. — Methods for sterilizing catgut. — Sterilization of silk, silkworm gut, kangaroo tendon. — Steril- ized dressings. — Preparation and sterilization of sponges. — Aseptic drainage. — (ilass drainage tubes and gauze drains. — A8e})tic irrigating fluids. — Dusting powders. — List of instru- ments for operations. 2 CONTENTS. PAIJK. CHAPTER V. Etiology in (teneral 57 Causes of diseases of women. — Training and uifects of education. — ^Personal habits. — Infectious diseases. CHAPTER VI. An.esthetics 62 Ciioir ^ of ana'sthetics. — Instructions to be observed in administration.^ — Methods of administration. — Treatment of dangerous symptoms during administration. CHAPTER VII. Examination in General. '. 68 (Jeneral outlines of dih'erential diagnosis. — Form for case taking. — Physical examination. — Methods of e>:amination. — Instrumeiiwtl examination. — Examination of interior of uterus and bla(hler. — C'ystoscopy. — Examination of ureters. CHAPTER VIII. Gyn/Ecolooical Therapeutics 86 (jreneral liygiene. — Special gyna'cological drugs. — Local therapeutics. — External and internal applications. — Medi- cated pessaries, tampons, and suppositories. — Applications to uterus. — Vesical injections. — ("uretting — Pelvic massage. CHAPTER IX. Post Operative Treatment 96 CHAPTER X. Gynecological Application of Electric Currents 1(X) Calvanic and Faradic currents. — Electrodes. — Galvano- meter. — Rheostat. — Diseases in which they are applicable. PART TWO. FUNCTIONAL DISEASES. CHAPTER XII. Disorders op Menstruation 107 Amenorrhd'a. — Vicarious menstruation. — Menorrhagia and metrorrhagia. — Precocious menstruation. — -Dysmenorrhd'a, neuralgic, congestive, obstructive, membranous, ovarian. CHAPTER XIII. Sterility. — Nymphomania. — Leucorrhcea 127 CONTENTS. PART THREE. DISEASES OF SPECIAL REGIONS. CHAPTER XIV. Diseases of the Vulva "j^^^ Malformations. — Hypogpadias.— EpLspadias. — Heinaph- rodism.- Hernia.— Hematocele.- Lijui ies. — Phlegmonous inflammation. —Cysts and absces.ses of the vulvo- vaginal glands.— Tumors— Vulvitis, simple, puruleat, follicular.— Eruptive diseases.-Pruritus.— Hypera^sthesia.— Kraurosis. — Coccygodynia. CHAPTER XV. Lesions op the Pelvic Floor 152 Causes of lo.ss of tonicity.— Prolapse of vagina.— Cystoc'ele -Rectocele. -Anterior colporrhaphy.- Posterior colpor" rhaphy.— Perineorrhaphy.— Colpo-perineorrhaphy.— Tait's Hegar's and Emmet's methods of perineorrhaphy. ' ' CHAPTER XVI. Diseases of the Vagina ...... 171 Malformations of the hymen. - Malformations of "the vaguia. -Atresia and stenosis. -Vaginitis.-Neoplasms. CHAPTER XVII. Genital Fistula. .^. Urinary tistuhe, vesico- vaginal, urethro-vaginal,' vesJcV- • uterme, vesico- utero- vaginal, uretero- vaginal, uretero- • uterme.— Fecal fistula. CHAPTER XVIII. Diseases of the Urethra and Bladder. . . 194 Malformations of the urethra. -Malformatmns of the bladde..^ -Irritable urethra.-Urethritis.-(Jranular erosion o urethra.-Stricture of urethra. -Urethrocele. -Irritable Wadder.-Cystitis.- Vesical calculi. - Foreign bodies.- : . JVeoplasms.— Ureters. CHAPTER XIX. Diseased of the Uterus Malformations. -Uterus unicornis.- Uterus bi'coi Uterus duplex. -Uterus septus. -Atresia uteri. 207 nis.- 4 CONTENTS. PACiE. CHAPTER XX. Diseases of the Uterus, Continued 218 Laceration of the cervix. — Trachelorrlmpliy. CHAPTER XXI. Diseases of the Uterus, Continued 219 Metritis. — ^Acute endometritis. — Acute metritis. — Endo- cervieitis. — Chronic corporeal endometriti.s. — Chronic me- tritis. CHAPTER XXII. Diseases of the Uterus, Continued 239 Accjuired atresia. — Stenosis of the cervix. — Hypertrophy. — Supra- vaginal amputation of cervix. CHAPTER XXIII. Diseases of the Uterus, Continued 241 Disphicements. — Anteversion. — Anteflexion. — Retroversion and retroflexion. — Pessaries. — Extra-peritoneal shortening of the round ligaments. — Alexanders operation. — Intra- ()eri- toneal shortening of the round ligaments. — Vaginal hystero- jiexy.— Abdominal hysteropexy. — Latero-versions and lat- ero-ttexions. — Prolapsus. — Inversion. CHAPTER XXIV. Diseases of the Uterus, Continued 261 Benign neoplasms. — Myxoma, glandular polypus. — Fibro- mata. — Myomectomy. — C<i4iotomy. — Abdominal hysterec- tomy. CHAPTER XXV. Diseases of the Uterus, Continued 276 Malignant neoplasms. — Cancer of the uterus. — Cancer of the cervix. — Vaginal hysterectomy. — Cancer of the corpus uteri. — Sarcoma. CHAPTER XXVI. Diseases of the Fallopian Tubes 292 Malformations. — Salpingiti.s. — Acute catarriial and puru- lent salpingitis. — Interstitial salpingitis. — Abdominal aal- pingo-oophorectomy. — Vaginal salpingo-oophorectomy. — Pyosalpinx. — Hydrosalpinx. — Ha-matosalpinx. — Atrophy of the tube. CHAPTER XXVII. Pelvic Inflammation 309 Pelvic cellulitis.— Pelvic abscess. — Pelvic peritonitis. CONTENTS. 5 CHAPTER XXVIII. Diseases of the Ovaries 320 xMalfoinmfcions.— Displacements.— ProIapHe of the ovary.— Hernia of the ovary.— Hypera-mia and haanatoma.— Acute oophoritis. CHAPTER XXIX. Diseases of the Ovaries, Continued 330 ^ C'hronicoophoricis.—Neopksms.— Cysts of the ovaries. - Small residual cysts. -Follicular cysts.— Cysts of the corpus luteum.— Tubo-ovarian cysts.- Proliferatingglandular cysts. —Proliferating papillary cysts. — Dermoid cysts. —Broad ligament cysts. —Ovariotomy.— Solid tumors. CHAPTER XXX. Ectopic Gestation ^ qkc Classification. -Tubal pregnancy.— Abdominal pregnancy. CHAPTER XXXI. Pelvic Hematocele and Pelvic Hematoma ..... 365 CHAPTER XXXII. Genital Tuberculosis 3-^2 CHAPTER XXXIII. Tuberculosis of the Peritoneum 377 PART FOUR. DISEASES OF THE FEMALE BREAST. ^ CHAPTER XXXIV. Anatomy.-The Nipples.-Neuroses.-Mastitis - Mammary Abscess.— Cysts 332 ., ; CHAPTER XXXV Neoplasms ^^^ Cla8sification.-Adenoma.-Fibro-adenoma.-Cvstic adj noma.-Papilkry cysts. -Sarcoma. -Adeno-sarc^ma. -Car- : " c.noma.-Scirrhus.-Encephaloid carcinoma. -Colloid car- cmoma. LIST OF ILLUSTRATIONS. FIG. PAGE. 1. Mullei'.s ducts l4 2. Coale.scence of ducts 14 3. Disappearance of septum 15 4. Ap{)earance of fundus and cervix 15 5. Virginal vulva 17 6. Shape and relative length of vaginal walls 19 7. Horizontal section in inferior strait of pelvis 19 8. Varieties of hymen 20 9. Virgin uterus 22 10. Muscular layers of uterus 23 1 1. Sagittal section of female pelvis 24 12. Blood vessels of the pelvis 26 13. Blood vessels of uterus and vagina 27 14. View of uterine appendages .... 28 15. Relations of ureters and uterine arteries to cervix 33 16. Muscles of perineum and pelvic floor 39 17. Shape of perineal body 40 18. Higbei -^ bivalve speculum 79 19. Sims' nculum 79 20. Simpsof "^ound 80 21. Bozeman .-- . essing forceps 81 22. Vulsellum forceps 81 23. Hanks' dilators 82 24. Goodell's dilators 82 25. Skene's endoscope 83 26. Skene's endoscope 83 27. Skene's endoscope 83 28. Double urethral dilator 84 29. Kelly's cystoscope . . 84 30. Kelly's obturator 84 31. Cystoscopic examination of the bladder 85 32. Burrage's cervical speculum 93 33. Intrauterine douche 93 34. Tenacula 94 35. Wire loop curettes 94 36. Sharp curette 94 37. Martin's cutivneous electrode 101 38. Bipolar electrodes 103 LIST OF ILLUSTRATIONS, i FIG. PA,~.E. SO. Dysmenorrhieal membrane 1'23 40. P olliciilar vulvitis 145 41. Cystocele and rectocele 155 42. Clover'.s crut'-h 158 43. Stoltz's operation for cystocele and Hegar'-i operation for rectocele 159 44. Operation for incomplete laceration of perineum Itil 45. Operation for laceration of the perineain and sphincter ani 162 46. Complete laceration of perineum extending into recto-vaginal septum 164 47. Diagram of o})eration for simple rupture of perineum 165 48. Diagram of oj)eration for complete rupture of perineum 165 49. Tail's flaj) splitting operation for incomplete rupture of perineum 166 50. Tait's Hap splitting operation for eom[)lete rupture of perineum. 166 51. Flap splitting operation -appearance of wound and introduction of sutures 167 52. Hegar's colpo-perineorrhaphy 168 53. Hegar's operation for complete laceration of the perineum 16') 54. Emmet's denudation in colpo-perineorrhaphy 170 55. Emmet's colpo-perineorrhaphy —sutures partially inserted 170 56. Atresia of the vaginal outlet 172 57. Double vagina 174 58. Operation for vesico-vaginal fistula 187 59. Des^elopment of the genito-urinary tract in the female 208 60. Uterus unicornis 209 61. Didelphic uterus and divided vagina 209 62. Uterus duplex . . 210 63. Two-cliambered uterus 210 64. Atresia of the cervix uteri 211 65. Unilateral laceration of the cervix 213 66. Bilateral laceration of the cervix, with eversion 214 67. Multiple stellate laceration of cervix 215 68. Edebohl's speculum 217 69. Lacerated cervix — surface denuded and sutures passed 218 70. Lacerated cervix with sutures tied 218 71. Erosion of the cervix 226 72. Amputation of cervix 238 73. (iehrung's pessary 243 74. Anteflexion of uterus with retropo'jition ... 247 75. Hodge pessary 250 76. Albert Smitli })e.ssary 2i';0 77. Thomas retroflexion pessary . 250 78. Procidentia uteri .... 254 79. Incomplete inversion of uterus 258 8 LIST OF ILLUSTRATIONS. FIC. PA(iF. 80. (Complete inversion of uterus 2.')8 81. I'olypus Mimulating complete inversion of uterus 2.58 82. Fibrous polypus of uterus 2.59 8.3. Interstitial fibroids of uterus 262 84. Subserous and submucous fibroids 262 85. Pedunculateu fibroid of uterus 263 86. Fibro-cysHc tumor of uterup 264 87. Application of litfntures in hysterecto.ay 274 88. Cylindrical epitiieliomn of the cervix uteri 278 89. Epithelioma of cervix uteri, vagina and bladder 279 90. Vaginal hysterectomy with ligature 283 91. Vaginal hj'sterectomy with clamps 285 92. Medullary cancer of body of uterus 288 93. Salpingitis with pelvic peritonitis and adhesions 295 94. Pyosalpinx and ovarian abscess 306 95. Ovary with dropsical follicles 328 96. Diagram of structures in and adjacent to the broad ligament. . 332 97. Small multilocular cyst 3.34 98. Microscopic examination of fluid from ovarian tumors 335 99. Papillomatous ovarian cyst 3.36 100. Dermoid cyst, showing plates of bone and long tawny hair. . . . 338 101. Unilocular cyst .340 102. Diagnosis of ascites from ovarian tumor 346 103. Ligature of pedicle in three sections 351 104. Staffordshire knot ... 352 105. Spindle-celled sarcoma of ovary. . . 355 106. Retro-uterine hannatocele 366 107. Primary tuberculosis of the tube.s and ovaries 373 lOS. Fibroadenoma of the breast 391 109. Proliferous cyst-adenoma. . 392 110. Section of a breast with scirrhus carcinoma 395 111. Scirrhus carcinoma of the breast 396 Medical and Surgical Gynaecology. PART ONE. PRINCIPLES OF GYNAECOLOGY. CHAPTER I. INTRODUCTORY. The term Gynaecology is understood to designate the afPections of the genital organs in the i ^male sex otlier than those immediately connected with pregnancy, child- birth, and the puerperal state, but clinically it is difficult to disassociate the one from the other, as the accidents and diseases arising diiring that critical period are the most fruitful sources of diseases peculiar to women. Great progress has been made in every domain of medicine. Every branch of it has felt the new impulse, but in no department has it been so marked as in this one. In tracing the development of modern gynaecology it is difficult to keep pace with, or even estimate the rapid l^rogress it has made. Twenty years ago it was a mere appendage to obstetrics, the teaching of it being limited to a few lectures at the end of the session ; to-day it is one of the most honored chairs in every medical curriculum. The teachings and practice of to-day bring hope and comfort to many a home which in days gone by would have been the possessor of a wife or mother or daughter doomed to hopeless invalidism under the label of " weak spine," "spinal irritation," "chronic ovaritis," "cellulitis," " irritable womb," and the like. 10 MEDICAL AND SURGICAL GYNyECOLOGY. Tlin/U^h itH advnncoK tlioro hns been given to suigery the oj)erfvtion for the removal of pelvic tumors, nnd to-day ovarian cysts are removed wiHi a mortality far below any other cajntal operation. The ingenioxis position of Tren- delenber!.? has rendered easy the total extirpation of uterine fibroids: the patiiology and op(>rative treatment of extra- uterine jjregnancy to-day snatches women from what then would have been considerotl the very jaws of death. Vesioo-vaginal and recto-vaginal listuhe yield readily to operation and permanent relief can with almost certainty be promised. Uterine cancer, the presences of which until very recently signed the death-warrant of the sufferer, is now treated with such good results as to far surpass the most sanginne expectations, offering at least an increased term of life and sometimes the total eradication of the disease. Chronic endometritis, once so intractable, now readily yields to the use of the curette. To gyniecology is due many of the advances in general surgery. From it has sprung the scientitic trentment of appendicitis, the surgery of the kidneys and gall-bladder, as well as that of all intestinal and visceral lesions. While recounting the triumphs recorded, it must always be a pleasant task to acknowledge the deejj debt of gratitude which gynecology owes to Sir Joseph Lister, for without his scientitic discoveries and brilliant teaching, the successes of modern pelvic and abdominal surgery could never have been won, and the announcement made that he has been raised to the peerage, has been received with the most lively feeling of satisfaction throughout the medical profession, which is proud to recognise him among its members and on which he has already shed so much lustre. While recognising that pregnancy and child-birth are fruitful sources of diseases in women, it is not by any means the greatest source. It is, therefore, the duty of every student of the subject not to be content with a INTRODUOTORy. 11 '.:uowl(Hlgu of the aotunl existence of diHense, but to study out the etioloj^icnl fnctors nnd the methods by which they mny be nmeiiorated, li^ssened, or prevented. A hir^e factor m.iv be found in faulty echication. Tlie chief strain of reproducing falls np'jn woman. She bears the burden of gestation, parturition, lactation, and of maternity, and for this great end she needs the most perfect physical development. The growth and well-being of her body should, therefore, be as carefully looked after as the growth and well-being of her mind, a concorddt in female education not sufficiently maintained. During girlhood days too much time is spent in the school- room, or in poring over books at home, when she should be at play. Just as womanhood is asserting itself, come the competitive examinations, which select the brightest and most intellectual, and who are often the most delicately constructed, for i)romotion to the high schools and universities. Two to four or even five years, most precious years for them, years needful for the perfect development of not oidy their general health but for the development of the reproductive organs and for the establishment of their functions, are spent in antagonism between brain growth and body growth. Possibly after leaving school, the worn out, rest-needing girl launches into the married state, and this young girl, wilting under the double strain of wifehood and motlierhood, remains ever after an invalid with her uterine and ovarian diseases, or with nerve prostration and its jjrotean mimicry of uterine symj)toms. Undoubtedly some of the worst forms of disease arise from specific infection by husbands, giving rise to sterility, miscarriage, oophoritis and salpingitis of every kind and degree, pelvic and intestinal adhesions, chronic ill-health, and even death. Probably the most common of all causes is the pre- vention of conception. By the methods adopted so much 12 MEDUAL AND SURtHCAL (lYN. ECOLOGY. en^orj^tMiiiMit and hy[)('ri)lnHifi and diHor^niiization of the uterine HtructurcH and appendages are apt to take plairo, that their hi^alth breaks down and they bee.onie (H)iupara- tive invalids. It is well to remembc^r, when consitU^rin^^ such important factors, that history does not forget to repeat itself. In the time of Julius Cjesar, celibacy and childlessness became more and more common; criminal abortion was frequently practisc^d; pregnancy was con- sidered a mar to beauty, and the Roman empire, for the want of tncn, was overrun by northein hordes. Greece, once the pride of the world, at last (juailed before the Roman Eagle and became a vassal because she could not brook to have her classic tastes interrupted by family cares and family ties. It cannot but be recognised that those who are the guardians of the public health are the guardians of the nation's prosperity and greatness, and this is doubly true in the case of the health of women who are to become the mothers of our future men, for unless their health and strength and well-being are preserved, the brain and bone and sinc^w of the country will, by progressive decadence, dwindle towards extinction. CHAPTER II. DEVELOPMENT OF THE FEMALE GENITALS. For a proper understanding of the malformations and diseases of the female genitals, it is necessary to be able to trace the various steps in their development. The ^Volffian Ducts are the first organs belonging to the genital sphere to api)ear. There is one on either side of the body and is situated between the proto-vertebral column and the lateral plates. Originally it is a solid cylindrical cell mass, but later becomes tunnelled. The upper end connects with the WolflSan body, the lower end DEVELOPMENT OF THE FEMALE GENITALS. 13 opens into tlmt pnrt of tiio nllantoiH situatt'd in tlu^ body of tho embryo nnd communicfttoH with the cloacn. In the female the Wolffian duct dinappearH mon^ or Ichh vom- ph^ti^ly, remnantH only of it beinj^ found in the broad ligannuits. The Wolffian Bodies are two long prismatic bodies, one on either side of tlu^ median line, nnd appear shortly after the Wolffian ducts. The lower end is fasttnied to tlu^ inguinal region by a liganuMit, which in course of time becoini^s the round ligament of thci uterus. These bodies originate from the mesothelial lining of tlu^ body cavity, and form at first a row of pear-shaped bodies. Lat(T they separate from it, acquire n lumen and form a row of vesicles, each of which soon connects with the Wolffian du(!t by absorption of the tissue betwecui their cavities and the bore of the duct. In the femah^ the Wolffian body is transformed into Jiost'tiviullcr's oiujdii or the pdroniriintt and stray tubes found between the parovarium and the uterus. The Ovaries. The sexual glands are situated on the inner side of the Wolffian body, to which they are fastened by a fold of peritoneum, the nicsordnKiii. The k)wer end is fastened to the Wolffian duct by a ligament which later beconuis the li<j(ini<'td of tlw ovarij. The blood vessels enter originally at the upper end of the mesovarium enclosed in a fold of peritoneum, which in time becomes the iiifundibnlu-ju'lvic ligament. To the outer side of the mesovarium is attached the mrsosdlpinx or mcsciitrrij of the tube which later is calh^d the ((l(( vcsju'i'filioni's (bat's wing), and contains the remnants of the Wolffian body, particularly the parovarium. The ovaries are also subject to descent. At birth they are above the ilio-pectineal line, and descend into the pelvis during the first two or three months of extra-uterine life. The Mullerian Ducts appear soon after the Wolffian body as an extended ridge of thickened mesothelium along 14 MEDICAL AND SURGICAL GYNECOLOGY. tho outer Hide of tlio upper (muI of the Wolffifui body. The lower part is nt first formed by n solid eolumii of cells v" ioh Inter becomi^s tuniu41ed so ns to form n tube. They form in the female the Fidlopiiiii tubes, ulie uterus, and vagina. Fi<;. I. — Mui.i.kk's nucrs. Kk;. 2.— C(iai.f.scknck of Ducts. The Fallopian Tubes are formed of that part of tin? Mullerian ducts which lies above tho round ligament of tho Wolffian body. The cells of tho wall form the fibrous muscular and mucous coats of tho fully developed tube, and fringes forming the jimbriiv grow out around tho abdominal op(^niiig. Uterus and Vagina. The part of tho Mullerian ducts b(4ow the round ligament, together 'with the lower end of the Wolffian ducts, forms a quadrangular cord called the (jcniUd cord. The walls between tho Mullerian ducts are absorbed and thus but one canal is formed. The genital cord is further developed so as to form the uterus above and tho vagina below. While the fusion of the Mullerian ducts is incomplete they are separated above, forming tho two cornud of the uterus, but lator form but one sac with- out horns. The Mullerian ducts open into the lower part of the nrachus — that part of tho allantois which is included in the body — and later forms the bladder. This lower part, situated below the openings of tho Mullerian and Wolffian ducts is called tho iiro-f/cnifdl sinus. Orig- inally this sinus opens into the cloacd, but later the septum is formed, dividing the cloaca and thereby separ- ating the uro-genital sinus from the rectum and the uro- genital opening from the anus, thus forming the perineum. DEVELOPMENT OF THE FEMALE OENITAL8. 16 The Urethra in (liftVn>iitinti'(l an a Hpocial organ from the bladder, with which it hcrotoforo formed one .sac ealU«d tht* urachuH. Tlio uro-gonital HinuH wiiieii Hoomod to be the continuation of tho bladch^r, now appi^irH as tho continuation of thi^ vaj^ina antl forniH the n'sflhiilr. Tho vagina is next separated from the uteruH by the formation of a ring and about the name time tlie cervix is being Fig. 3.— Disappearance nr Septum. 4.— Appearance oi-- Kunuus and Cekvix. diHtinguislied from the body of tlie uterus. Tlie vagina becomes mucli wi(U^r, its rolimins and rn(/(i' make their appearance, and later the lii/mcn is formed by ;. develop- ment of the posterior wall of the vagina. The Vulva. Originally the uro-geuital and digestive tracts open into one common cavity, the clo(U'<i. The cloaca opens on the surface of the body by n slit calU^l tho cloacnl opening. In front of this opening app.ears an elevation called the (fcnitdl iuhn'vlc, surrounded by two folds calked the f/cniffd folds. A groove is formed on the lower surface of the genital tubercle, called the (/cnitdl fur'vow. The genital tubercle becomes tho clitoris; the genital folds, the l((l)i((. majora; the edges of the genital fold, the l((hia minora, a fold of which surrounds tho clitoris forming the prepuce. The separation between tin uro-genital sinus and the rectum is completed; the genital folds grow together at their posterior end and unite with the partition or septum between tho uro-genital sinus and the rectum to form the perineum. 16 MEDICAL AND SURGICAL GYNAECOLOGY. CHAPTER III. ■ * ANATOMY. THE PELVIS. Four bones, two ossa hmnmincifa, the sacrum, and the coccyx take part in the formation of the pelvis. The pieces comprising the innominate bone — the ilium, iscltiiini, nnd pubis — in early life are distinct, but later are fused into one. The space included within these bony walls is divided into two parts, the part above the ilio- pectineal line is called the false pelvis, and that part below, the true pelvis. The true pelvis is a short curved canal, whose superior strait, inlet or hrini is bounded behind by the promontory of the sacrum, laterally by the ilio-pectineal lines, and in front by the ujjper margin of the pubis. The inferior strait or outlet is bounded behind by the tip of the coccyx, laterally by the tuber-ischii, and in front by the lower border of the pubic bones. The plane of the inlet, when the body is in an erect position, forms with the horizontal an angle of about forty-five degrees. The aju's of the inlet if directed up- ward would pass through the umbilicus, and if prolonged downward would touch the tip of the coccyx. 7Vie axis of the outlet if extended upward would meet the prom- ontory of the sacrum. The bones are united with one another by four articulations, one in front between the two pubic bones, the synij)htjsis pubis; two laterally between the lateral surface of the sacrum and ilium, the sacro-iliac; and cue behind between the sacrum and coccyx, the sacro-coccy</eal. In addition to the ligaments which bind these bones together, there are two important ones closely associated with the boundary of the true pelvis— the (jreater and lesser sacro-sciatic ligaments. ANATOMY. IT THE FEMALE ORGANS OF GENERATION. The Genital Organs are divided into two groups: the external to which belong the mans veneris, the vulva and the vagina; and the internal to which belong the uterus, the Fallopian luhes, and the ovaries. The Mons Veneris lies in front of the pubic bones just below the hypogastric region. It is composed of stout integu- ment, abiindniitly suj^pliod with crisp hair and a thick cushion of subcutaneous adi- pose and areolar tissue. The liair is limited above and does not extend to the umbilicus as i'.i man. The Vulva forms and sur- rounds the entrance to the genital canal. It is made up of the labia niajora, with the fonrehetfe; the labia minora with the clitoris ; the vestibule with the bulbs ; the fossa Fig. 5. — Virginal Vulva : i, la!>ia majora ; • j • 1 ii T 2, fourcheite; 3. lal.ia.ninora;4,Slans naVICUlariS; aud the VUlVO- ciiloridis ; 5, meatus iirinarius ; 6, vesli- "77 I luile; 7, entrance to the vagina; 8, Vaf/in((t (fKUiaS. hymen ; 9, orifice of H.irtholin's ghmcl ; 10, ant. rior commissure of labia majora ; The Labia MajOra afC tWO 11, anu ; 12, blind recess; 13, fossa •* navicularis; 14, body of clitoris. COUSpicUOUS loUgitudiual folds of integument Dne on either side of the median line, extending from the mons veneris to within about an inch in front of the anus. The outer surface; is covered with pigmented epidermis and scattered hairs; the inner sur- face is smooth, rose-coloured, more delicate in texture, and where least exposed partakes of the character of a mucous membrane. The point at which they unite in front is called the anterior commissure, and behind the posterior 18 MEDICAL AND SURGICAL GYNAECOLOGY. commissitrc. Immedintely within the posterior commis- sure, a cresceutic fold extends trnnsversely, the fourchcttc. The space between the fonrcliette and the posterior com- missure is the fossd ii(iriciil((ri)^. Each labium includes A'ithin it areolar tissue, uustriped muscle fibre, and con- siderable fat, and together are the homologues of the scrotum in the male. The Labia Minora or Nymphae are two thin diverging folds of delicatt^ skin on the inner side of the labia majora. Just before meeting in front, each divides into two leaf- lets, the outer or upjier leaflet of each pasting over the clitoris to unite and form the prepuce; the inner or lower leaflet passing beneath to form the frciuun. They extend back to about half way between the clitoris and the posterior commissure, gradually merging into the sides of the vaginal orifice. The Clitoris is a small cylindrical body about an ip.oh long situated in the median line below the anterior com- missure. It is composed of the (/kins, a pointed tubercle which forms the end and is the only part visible, and the bodij which consists of two distinct corpovd cavernosa attached to the symphysis by the suspensory ligament and by their crura to the rami of the pubes. It is supplied with erectile and muscular tissue, in diminutive similar to that of the male, and has a prepuce and frenum formed by the labia minora. The blood supply comes from the internal pudic, the same as in the male, and the lymplKdics empty into the inguinal glands. The Vestibule includes the triangular space between the clitoris, the labia minora, and the entrance to the vagina. Its smooth mucous surface is broken in the mid- lino about one inch behind the clitoris, by the urethral opening or mecdus urinarius. The Vestibule- vaginal Bulbs are two leech -shaped organs, one on either side of the vestibule and together are equivalent to the bulb in the male urethra. ANATOMY. 19 Fig. -S..ape and relative length of vaginal walls. The Vulvo-vaginal or Bartholin's Glands nro two small round or ovnl bodies situated on either side of the entrance to the vagina at the posterior end of the vestibulo - vaginal bulbs_ They are r a c e ni o s e glandsjSecreting a mucous fluid. The Vagina is a mus- culo-membranous canal lying chiefly within the cavity of the pelvis and exttuuling between the vulva and the uterus. It pierces the pelvic floor at its lower end and is in relation with the blad- d«^r and urethra in front and with the rectum behind. The (uis while corresponding in general with that of the pelvic cavity, presents a double or S-like curvature. When not distended it is fold- ed, the anterior and posterior walls being in contact so that in cross section it resembles in shape the letter "H." When distended it is in the form of a truncated cone, the apex at the vulva. The lower end dips into the vulva by a circular opening surrounded by the consfrietor Vdjfina' muscle. The upper end forms a cup to receive the vaginal portion of the uterus, and in its adaptation to the parts forms a shallow pouch in •^■fcr"X'inL:;i;"'s;;:!i;'of^!: front and behind, the autrrior ^^In^Tr:^^^^^^:^ J^' 20 MEDICAL AND SURGICAL GYN^COI.OGY. niul ])osferi()r forniccs. In the adult virgin the anterior wall is about two and a half inches long and the posterior about three and a half inches, but after child-birth these dimensions are increased. Fif" 8.— Varieties OK Hvmen : Virgin hymen, i,conunonesl form (annular); 2, liynien after coitus ; 3, after delivery ; 4, fimliriate liynien ; 5, hymen with narrow slit ; 6, cribriform hymen ; 7, hymen with septum ; 8, horseshoe form. ANATOMY. 21 In Hfrurfiirc the whUh of tlio vnj^iim consist of a silicons mcmbrfvno, covmul by stratified stiuanivHis opitlui- lium nnd i)ossossins numorous papillio; a muscuhtr layer inado up of longitudinal and circular fibres; and a_///>/-o?/s tunic of rich fibro-clastic tissue derived from a prolonga- tion of the recto-vesical fascia. The mucous membrane of the anterior wall is thrown into folds or rmja' and a less distinct formation is found on the posterior wall. They are called the (inferior and posterior eolnmns. The blood supphj is derived from the vaginal, uterine, vesical, and internal pudic arteries. The Jijmphdtirs from the lower fourth join the lymphatics of the external genital organs and end in the superficial inguinal glands. The lymphatics of the upper i)ortion proceed outward with the broad ligament and joining with those from the oviduct and ovarie.'; terminate in the lumbar glands. The nerves are derived from the inferior hypogastric plexus of the sympathetic and from the fourth sacral and pudic nerves. The Hymen is a fold of mucous membrane which closes more or less completely the lower opening of the vagina. It varies much in shape, the most common being two lateral strips which touch one another in the middle line. Sometimes it forms a ring with a round opening, sometimes a crescent, and sometimes it is represented only by a low circular or crescentic ridge, and not unfrequently the border is indented, which condition is not to be con- founded with a iacerated hymen. At coition the hymen is usually torn, but at first child-birth it is so destroyed as to leave only three or four roundish prominences called the c((niiirnJ<t' mjjrtlformes. The Uterus is a hollow flattened pyriform muscular organ situated between the vagina below and the intestines above, and between the bladder in front and the rectum behind. It is about three inches long, one and a half inches at its greatest width, and one inch in thickness. 99 MEDICAL AND SURGICAL OYN^ECdLOGY. Of the entire organ, three-fifths belong to the upper part or hotli/ nud two-fifths to the lower part or neck. The body is ahnost fiat on its anterior surface but distinctly convex beliind; the uj)per border is rounded and con- stitutes the/?///Y//^s,• the lateral borders are slightly convex and mark the attachment of the broad ligaments. The neck or vtrvi.r, spindle-shaped in its general outline, is divided into the vdijinal portion, or that part which projects down into the vagina, and the snpravcKjimil portion. The vaginal portion is covered with squamous Be Kit;. 9. — ViKGiN Utekus. A. .Vnterior view. B. Median section. C. Lateral section, epithet i II tti. the same as covers the mucous membrane of the vagina, and at its lower end is a transverse or rounded operung, the os cxterninn or os uteri. That j)ortion of the cervix in front of the os forms the (interior lip, and that behind the poi<terior tip. The interior of the uterus contains a cavity, the uterine earitij. about two and one-half inches long. That portion within the body is triangular in shape wlien viewed from in front, the expaiided base extending between the orifices of the oviducts and the apex corresponding with the upper opening of the cervical canal, or os internum. _ _ .- ANATOMY. 23 Tluit portion within the c.orvix is fusiform in shape and on its anterior and posterior walls are found ridges separated by (h'ep pouclies which go outward and upward and form the (u-hor niUv or palrmv plirativ of the uteruB. Structure. The uterine wall is about three-eighths of an inch thick anil is composed of three layers, a mucous, a muscular, and a serous. The miirosd lines the whole cavity and consists of a fKnicd-propria covered by a layer Fig. io.— AiUtrior Surface of the Uterus, Superficial Layer. I., Ruiiiid liRaiiient ; T, Tube ; I, iniddle layer ; 2, transverse fibres ; 3. fibres of the rotiml ligament which have spread over the anterior surface of the uterus ; 4, fibres arising from the posterior portion of the round ligament which form loose fohls l)efore they join the median fasciculus; 5, fibres of the cervix uteri ; 6, oblique fibres. of ciliated columnar cells. Numerous tubular depressions, the utricular (jlands, lined with ciliated ei^ithelium are found in it. In the cervix the mucosa is thicker, and in addition to the tubular follicles, racemose glands lie within it. Its upper two-thirds is covered with ciliated columnar and its lower one-tlnrd with stratitied squamous epithelium. The niHscitlar coat is divided into three layers, an outer longitudinal which sends prolongations into the oviducts, 24 MEDICAL AND SURGICAL GYNAECOLOGY. niul the round, ovnrinn nnd sncro-utorino ligaments; a middle layer of iuterlaciiij^ longitudinal and circular fibres, which are in connection with the muscular coat of the vagina; and an internal traiisverse layer, the lower portion of which is especially develoi)ed to form a sort of sphincter at the os internum. The serous codt is formed by the usual constitutonts of the peritoneum. Position. The exact position of the uterus in the living subject is a much discussed question. It may be Fig. II. — Diagramni.itic sagittal section of the female pelvis. _ u, uterus; r, rectum; s, symphysis ; v, perineal body ; ii, is beneath bladder. This is the position of the uterus when the ' ladder is almost empty. said that the fundus reaches a little above the brim of the pelvis and lies a little to the right side. With the rectum and bladder empty, tlie longitudinal axis of the uterus forms a right or obtuse angle with that of the vagina. The Supporting Apparatus of the uterus consists of eight ligaments composed of folds of peritoneum or mus- cular bands or of both passing from the uterus. The vesico-utcrine are two small semilunar folds of peritoneum. ANATOMY. 26 ono on either side of tlio moclinn line and pnHsinfjf from the bhuhler to the uterus on a kivel witli the iutemnl os. The sdcro-ufcrine nre fohls of peritoneum passing from the cervix to become continuous with the serous covering of the second portion of the rectum. They form the lateral boundaries of Douf/ldi^' j)oi(ch. Between its layers unstriped muscle fibres derived from the outer layer of the uterus extend from the upper part of the cervix to the second sacral vertebra. The lateral or broad ligaments are two wide duplica- tures of peritoneum, one on either side, extending from the side of the uterus to the pelvic wall, forming a jjartition between the anterior and posterior pouches. Each jjresents four borders. The superior or free border encloses the oviduct as far as its fimbriated end and then diverges towards the pelvic wall to form the infnmUbnlo-pelvic ligament. The inferior border is attached below to the recto-vesical far jia and to a mass of connective tissue lying at the side of the cervix, called the parametrium or parametric connective tissue. The internal border is attached to the side of the uterus, and the external border to the side of the pelvic wall where it is continuous with the obturator fascia. This ligament has two layers, an anterior which covers the round ligament, and a jjosterior in which there is an opening for the insertion of the ovary. Between the layers are found the blood vessels, nerves and lymphatics, together with the parovarium, the paroophoron, and unstriped muscle fibres which pass from the uterus to the pelvic wall. The round licjaments, one on each side, are attached to the upper segment of the uterus, below and in front of the oviducts. Each proceeds in a curved direction, first upward and outward, then inward and forward to the internal inguinal ring, through which it passes. After traversing the inguinal canal it emerges at the external inguinal ring to blend with the tissues of the labium 2(i MEDICAL AND HUIUIICAL OYN.ECOLOOY. mnjus. Th(i li^'niiuMit consists of bundlos of oonnootivo tiH8u^^ mid uiiHtriiH^d inuscK" Hbrt> dorivud from tiu^ utoruH. It at first runs uiid(^r the aiitorior liiyt^r of tlu^ brond liKiimont, but nftorwards lias a poritotieal covoring of its own which, as a rule, stops at the inner rin^. Occasionally the pouch of puritoiunim accompanies it through the ring, forming the cdtuil of Nuck, corresponding to the processus vaginalis in the male. Fk;. 12.- Hlooil-vessels of the pelvis; the anterior part of t.'ie pelvis has been removed, and the bladder an<l the anterior vaRinul wall have been partially cut away. The uterus is drawn up and the Kall-jpi' 'ubes are displaced into the iliac fossic. Blood Supply . The uterine arteries derived from the internal iliac pass behind the peritoneum on the posterior wall of the pelvis down into the parametrium and form loops in front of the ureters a short distance from the antero-lateral fornices of the vagina. They then pass up between the two layers of the broad ligaments following ANATOMY. 21 the edges of the uterus ns fnr ns the corriuii, uiul in their course they send off at ri^lit jin^U'S brmiehes to the uterus. At the ititenial os brnuclies in front nml behind form, by nn unnHtomosis, the circular artery. P"u;. 13. — The ovarian, uterine and vaginal arteries. The hjinphdlics commence in the endotJielium, those from the cervix passing to the obturator glands, and those from the body to the internal iliac glands. Nerve Supphf. Branches from the second, third, and fourth sacral nerves join with branches from the hypo- gastric plexus to form a ganglion on either side of the 28 MEDICAL AND SURGICAL OYN.ECOLOOY. corvix. From thin ^an^lioti, brnnchw nro (liHtributtHl to tlio utcruH, vaK'ini 'i'>'l bladder. The Fallopian Tubes or Oviducts an^ two loii^ HliMider tubcH which (wtciid from tho Huiu'rior aii^h'H of th(^ iitoruH witliiii and aloii^ tho free inar^iuH of tho broad lij^arnoiitH for a diHtauce of from throo to five inches to tho vi(^iiiity of the ovaricH, where each terminates in n funnel- 8hap(Hl orifice, the itifnndihiilum. Ea(^li tube is divided into three parts. Tlie isthnivs com- prises about the inner third, and communicates witli the uterus by the osliiun internum, an ojjening so small as barely Fio. 14. — Posterior View of Left Uterine Appendages: i, uterus; a, F.nllopian tube; 3, Fimbriated extremity and opening it the Fallopian tube ; ^, parovarium; 5, ovary ; 6, broad ligament ; 7, ovarian ligament ; 8, infundibulo-pelvic ligament. to admit a bristle. The amjinlla or middle part is twice as thick, curved, and follows a 8eri)entine course. Its calibre will admit a uterine sound. The jimhrim are the outer- most part, and surround the outer end of the ampulla like a collar with long flaps. One of these, the Jimhria ovarica, is attached to the free end of the ovary and forms a gutter. In the middle of the fimbria) is the outer opening or ostium abdomvi ale. ANATOMY. .89 Structure. Tlu^ oviductH nro mndo up of tliroo coats. The mucouH, contiiiuouH with thnt of tho utoruH, proHonts numorous lon^itui'innl foldn whivh increriHo in sizo and comph^xity within thi^ infundibulum, and in lir.od by a Hinghi layer of (uliatiul cohimiiar (ipithdiuin. The muacuJar is made up of an inner (circular and an outer h)ngitudinal layer of uuHtriped muH(!le Hbres continuous with the muscular coat of the uterus. Tlu^ serous coat consisls of the peritoneal investment contributed by the upper free margin of the broad ligament. The Ovaries are two oval bodtes situated by tlie s'de of the uterus, bel(.w, beiiind, and to the inner side of the oviducts. Each ovary appears as an apptuidage on the posterior surface of th-* broad ligament. The anterior border alone is attacheil, being inserted there in a hole, as it were, in the posterior layer. The arched posterior border 'i id tlx broad surfaces are covered with hexagonal columnar epithelial cells, the (jcrtuinal epithelium. The dimensions vary considerably with the individual but they usually measure one and one-half inches long, one inch wide, and half an inch thick. The smaller or lower end of the ovary or uterine pole points toward the uterus, to which it is united by a Pbro-muscular band about one inch long, the ovaridu liijaiiient. The upper (uid or tubal pole after being embraced by the arching oviduct receives the lower border of the fimbriated extremity of the oviduct, and is further connected to the wall of the pelvis by the infundibulo-pelvic ligament through which the blood supply is conveyed to the ovary by means of the ovarian artery, a branch of the abdominal aorta. Structure. The ovary is divided into an outer part, the parenchymdtous zone or cortex, and an inner, the vascular zone or medulla. The viortex contains the Graafian follicles, and the ova, and occupies the outer one-third of the organ. The medulla embraces the remaining central portions of the organ into which the 30 MEDICAL AND SURGICAL GYN.ECOLOGY. V^lood vessels enter through the hilum. The bulk of the organ consists of peculiarly arranged connective tissue and of unstriped muscle fibre, the ovar inn stroma, in which lie embedded the Graafian follicles. Bener '}\ the germinal epithelium it forms a layer of greater density than the adjacent stroma, to which the name tnnicd (Uhiujinca is applied, but it is not an independent envelope. Under the albuginea is found a zone distinguished by the presence of small follicles containing an ovum, the so- called ovisacs or young Graafian follicles. Inside this zone is found another with much larger Graafian follicles. The medulla is composed of connective tissue and unstriped muscle fibre, but much looser in its arrange- ment, and in this the blood vessels are freely distributed. There are usually from six to twelve large follicles in an ovary and it is simply by their increased size that they seem to form a zone inside the smaller ones. In growing they push the surrounding tissues aside, extend deep into the interior of the ovary and at the same time come closer to the surface, until finally all tissue between the follicles and the surface is absorbed aud they are then ready to burst. The mature Graafian foUicle appears as a clear elongated vesicle defined from the surrounding tissue by a condensed layer of ovarian stroma, the theca follicnli, which by some is described as composed of two layers, an outer of connective tissue, the tunica fihrosa, and an inner composed of cells and a tine net-work of vessels, the tunica propria. Within these are several layers of epithelial cells, the mcmhrana (/ranulosa, and on one side these cells form a i)rotruding . ass into the cavity called the discus prolifcrus. The follicle contains a fluid, the liq-iior follicnli. In the discus proliferus is embedded the ovum, about O.B m.m. in diameter, inside of which is found a fine membrane, the zona pellncida, or vitelline membrane. The interior is filled with a semi-fluid, the ANATOMY. 31 vitellus, inside of which there is a small vesicle, the germinal vesicle, and within this is found a little round body, the (ferniinal ■ j>of. On the escape of the ovum the ruptured and partly collapsed follicle becomes filled with blood. Subsequent changes lead to the conversion of the follicle into a corpus luteum, the chief changes in which being produced by the ingrowth and rapid proliferation of the vascular tissue of the follicular wall. The history of the corpus luteum is naturally affected by the occurrence of ijregnancy, instead of being almost entirely absorbed within a few weekn, when fertilization takes place it persists until the end of gestation. It is usual, therefore, to distinguish between the corpus luteum of menstruation and that of jiregnancij. The mode of growth is identical in both, the stimulus of impregnation leading usually to excessive development. The Parovarium or Organ of Rosenmuller, a remnant of the Wolffian body, is situated within tlie two layers of the broad ligament, between the outer end of the ovary and the oviduct. It consists of a series of from six to twelve spiral tubules, lying irregularly parallel, and made up of connective tissue, unstriped muscle fibre and columnar ei)ithelium. Additional festal remains in the form of rudimeiitar tubules are found within the broad ligament near the ovary and constitute the parooptioron. URINARY ORGANS. The Female Urethra is sliort, being only about o^^^, and one-half inches long, and lies beneath the symphysis pubis, firmly embedded within the anterior vaginal wall. It descends from the neck of the bladder in a slightly curvtnl direction, the concavity being forward, to the vestibule, where it terminates in the meatus urinarius. It is surround(Ml by the compressor urethra- muscle and has a sphincter at the meatus. It is about a quart(*r of an 32 MEDICAL AND SURGICAL GYNvECOLOGY. inch in dinmetor, but owing to the elastic chnrncter of its tissues is capable of great distension, a feature of much advantage in examination of the bladder. The mucous membrane is covered with stratified transitional epithelium, and tubular glands occur near the vesical end. Two small tubes, Skene, s (jlands, lie within the muscular wall and open into the urethra a short distance above the meatus. The Bladder is placed betwc-n the pubic bones and the vagina and uterus. When empty it is situated in the true pelvis and is flattened or "Y" shaped; when distended it reaches more or less into the abdominal cavity and is ovoidal. The hdse or fundus is the lowest part of the organ and is connected to the anterior wall of the vagina and to the neck of the uterus by rather firm connective tissue. Three openhHjs are found in it. In front is the internal opening of the urethra, and behind tliere are two fine lengthy slits, where the ureters open into the bladder. The triangular surface between these three openings is called the triijone. The anterior surface has no peritoneal covering and lies against the pubic bones. The posterior surface is covered witli peritoneum down to the level of the internal os. It has three coats, a serous, derived from the peritoneum; a muscular, composed of an outer long- itudinal, and an inner circular layer of unstriped muscle fibre; and a mucous coat which is thrown into folds when empty. This coat contains numerous lacunar and race- mose (jlamls, and is covered with stratified transitional epithelium. Lifjaments. The bladder has four true ligaments, two anterior, running from the lower part of the pubis to the anterior surface, and two lateral, from the outer margins of the anterior ligaments to the sides of the bladder. The false ligaments, five in number, are folds of peritoneum. The two posterior are me vesico-uterine ligaments. The lateral extend from the iliac fossro to the sides of the ANATOMY. 33 bladder, and the siiperior extends from the summit of the bladder to the umbilicus. The Ureters are two tubes leading from the kidneys to the bladder. They are from sixteen to eighteen inches long and about the size of a goose quill. Starting at the pelvis of the kidney, they run down parallel with each other to the brim of the pelvis and there crossing the iliac vessels slightly below the division of the common iliac Fig. 15.— Relation of the Ureters and Uterine Arteries to the Cervix : U, uterus ; Ur, ureter ; A V, uterine artery ; C, cervix uteri ; /', section of the liladiler at the level of the entrance of the ureters through its walls ; Va, vagina. arteries, enter the pelvis opposite the sacro-iliac synchon- drosis. They run on the wall of the pelvis backward, downward, and a little oiitward behind the peritoneum to a point near the spine of the ischium. They then bend down- 34 MEDICAL AND SURGICAL GYNECOLOGY. ward, forward, and inward to converge towards tlie bladder. They lie outside the internal iliac arteries behind the broad ligaments, running down to their base and tlien under them. They cross the cervix from behind at an acute angle, about one-half inch distant, so as to come in front of and below it. On reaching the wall of the bladder they turn sharply inward and run for half an inch in its wall, finally opening with a sT^nll longitudinal slit in the interior of the bladder. The Rectum is formed by the lower end of the large intestine and extends from the brim of the pelvis to the anal aperture. It is from six to eight inches long, and when empty is one and a half inches wide, but is capable of enormous distension. For convenience of description it is divided into three parts. The upper or first portion extends downward, backward, and inward to the third sacral vertebra, and is covered entirely with a fold of peritoneum, forming the moso-rectur ' . The second portion turns forward and extends as far as the tip of the coccyx, but is covered with peritoneum in front only, (Douglas' pouch.) The third portion, about an inch from its end, turns downward and backward at a right angle to the axis of the vagina to terminate in the anal orifice. It has no peritoneal covering whatever. Structure. Besides the peritoneal covering already described, it has a muscular coat formed of an outer longitudinal and an inner circular layer of unstriped muscle fibre. At the lower end the longitudinal fibres are intimately interlaced with the levator (ini, and inter n<d antl extermd sphincter muscles. The external sphincter is a voluntary muscle and surrounds the anal opening. It is attached behind to the tip of the coccyx, and in front it blends with the transversus perinei and the sphincter vaginae muscles. The internal sphincter is only a thicker part of the circular layer of the rectum and surrounds tl <> anal canal inside the external sphincter. The mucous ANATOMY. . 35 coat, thrown into numerous folds when the rectum is empty, is covered with columunr epithelium and has many glandular pouches. Rcldtions. The upper part of the rectum is separated from the uterus by loops of small intestines; lower down it is in close contact with the cervix and vagina, and at the end it forms the posterior wall of the perineal body. The Pelvic Peritoneum is a continuation of the abdominal peritoneum and covers more or less completely the organs in the pelvis. In front it passes from the anterior abdominal wall to the summit of the bladder, which it covers as well as the posterior wall down to the level of the internal os. From there it is reflected over the anterior surface of the uterus and the fundus. It then covers the whole of the posterior surface and extends down behind the posterior wall of the vagina for about an inch. It next passes over to the rectum, leaving a pouch between the two folds, Douglas' pouch or the recto- uterine pouch. From the side of the uterus the Ijeritoneum passes out to the walls of the pelvis, forming the broad ligaments. The uterus and broad ligaments together divide the pelvic cavity into an antero-inferior and a postero-superior part. In the anterior compartment or utero-alxloiniudl jiouch, we find the utero-vesical and round ligaments. Its lateral parts, ojjjjosite the obturator canal, have been called the obturator or pord-vesical pouches. The pos- terior compartment is divided into a central deep part, Douglas' pouch, and two shallower lateral parts or pora- nterine pouches. The bottom of these has been designated particularly as the retro-ovarian shelres. The sacro- uterine ligaments, one on each side, form the boundaries between the three compartments. On the side wall of the para-uterine pouch is seen the ureter running under the peritoneum. The ovaries project into these pouches and besides contain loops of small intestines. 36 MEDICAL AND SURGICAL GYNAECOLOGY. Pelvic Connective Tissue. Loose connective tissue is found everywhere underlying the peritoneum, forming one continuous layer. In some plnces it contains adipose tissue. Just above the symphysis there is a layer, the pre-])eritone(d fat, continued behind the symphysis as the retro-pubic fat. Between the base of the bladder and vagina there is a tight layer of connective tissue and on the front surface of the vagina there is a loose layer. A large mass of connective tissue is found on both sides of the cervix, forming under the broad liga- ments the p(i7'(i,metri(i. From the parametric region a thin layer extends between the folds of the broad ligament, and from there is continued into the iliac fossa and lumbar region. The Pelvic Floor. Under this heading there remains to be considered three important structures, the pelvic fitscia, the pelvic (Uaphnujm, and the perineal region. The Pelvic Fascia is a continuation of the iliac fascia. It is attached to the iliac part of the ilio-pectineal line, and to an oblique line on the posterior surface of the pubic bone. It descends on the inner side of the pubes and ischium about half way down, where a strong sinewy cord, the lohlte line, or tendinous ai :li, extends from the spine of the ischium to the pubic bf le. That part of the fascia covers the obturator internus and is called the ohturdtor fascia. At the arch the fascia splits into two layers, an upper, called the recto-vesical fascia, which bends inward over the levator ani; and a lower, which follows the obturator internus to the edge of the ischium and pubes, keeping the name of the obturator fascia. At the tendinous arch at the upper insertion of the levator ani, the fascia gives off another layer which runs on the outer surface of that muscle and is called the anal fascia. Together with that portion of the obturator fascia lying below the line, the anal fascia forms the lining of the ischio-rectal fossa, and is called the ischio-i'ectal fascia. 'rj*! ANATOMY. 37 The recto-vesicnl fnscia covers the upper surface of the levator aui down to the base of the bladder, the vagina and rectum. In front a layer forms the anterior, and on the side, the lateral true ligaments of the bladder. From the under surface of the recto-vesical fascia a prolongation surrounds the vagina, and forms a strong ring around the vaginal entrance where it joins with the deep perineal fascia. From the spine a band goes to the rectum, which follows the rectum down as a sheath and disappears around the anus. By its distribution the pelvic fascia forms an irregular fibrous layer under the peritoneal cavity, strengthening the pelvic floor and giving support to the organs found in it. I Pelvic Diaphragm. Under the pelvic fascia is a horse-shoe-shaped muscular expansion, open in front, formed by what is generally described as two muscles, the leiHitor ani and the coccygeus. It is attached above t;> the jjosterior surface of the pubic bones, to the tendinous arches of the pelvic fascia, to the front of the spines of the ischia, and lesser sacro-sciatic ligaments. From these attachments the anterior portion goes backward and inward, on either side, some fibres to be attached to the urethra; some cross the vagina and are interwoven on its lateral aspects with its structures; some loops go from side to side between the vagina and rectum, but the greater jjart joining with the fascial portion goes behind the rectum, grasping the end curve of that tube and supporting it. The posterior fibres are inserted into the side of the sacrum and coccyx. Function. It strengthens the pel /ic floor and forms a strong bed on which rests the uterus and bladder. It is the antagonist of the thoracic diajihragm, being relaxed in inspiration and contracted during expiration, as may easily be seen with a Sims' speculum in the vagina. It lifts the rectum up during defecation and exercises a similar function for the vagina during childbirth. 38 MEDICAL AND SURGICAL GYNECOLOGY. The Perineal Region is somewhnt rhomboidal in shape and is bounded by the rymphysis and descending rami of the pubes, by the tuberosities and ascending rami of the ischium, and by the lower edge of the gluteus maximus and tip of the coccyx. It may be subdivided by a line drawn across in front of the tuberosities into two jjarts or triangles, an anterior or uro-yenital, and a posterior or anal region. Perineal Fascia and Ligaments. The anterior or uro-genital region has beneath the skin and adipose tissue, n layer of dense connective tissue called the superficial pcrincxd fascia, analogous to that in the male. Beneath this there is another layer, the deep perineal fascia or triangular ligament. It has two layers, a superficial attached at the sides to the rami of the pubes ischium, and in front to the pubic bones, behind it is continuous with the superficial perineal fascia and with the deep layer. The deep layer is likewise fastened to the rami of the ischium and pubes. In front it is continuous with the recto-vesical fascia, behind it is continuous with the anal fascia on the lower surface of the levator ani. It is jjerforated by the urethra and vagina. Where the superficial perineal fascia and the two layers of the deep meet behind, they are fortified by a strong transverse band, the isehio-perineal ligament. In the anal region the anus forms an opening in the median line between the nates, and is there surrounded by its sphincter. Between the rectum and the ischium is a pyramidal space, the ischio rectal fossa. ' Perineal Muscles. Situated beneath the superficial perineal fascia there are three pairs of muscles. The ischio-cavernosus or erector-cliforidis is attached at one end to the ramus and tuberosity of the ischium, covers the corpus cavernosum, and at the other end is attached to the free part of the clitoris. The hulbo-cavernosus or sphincter vagina', receives some fibres from the external ANATOMY. 39 Hiihincter niul suporficinl traiiBvorsus perinci, pnsHos for- wnn' on either side nud is attnclied, one part into the posterior aspect of the bulb, another on the mucous membrane between the clitoris and the urethra, and another on the lower surface of the clitoris. The superfwidl trans- versiis perinci is attach- ed to the tuberosities of the ischia and to the median raphe. The deep muscles in the uro-geni- tal region are not well developed. They are the compressor urethra', the deep tnmsversus perinei, and the con- strictor vagina', all situ- S^ ated between the two layers of the deep perin- eal fascia. The Perineal Body is the name given to the tissues comprised between the genital canal and the rectum, below the point where it turns backward. In shapr it is not always the same. Sometimes it is triangular, with the base down, in some it has an ui^per narrow and a lower broad part, and in others it is : ^arly quadrangular, or has the shape of a quadrant of a ci.cle. In structure it is composed of the posterior ends of the bulbo-cavernosus, the fibres of the transversus perinei, the external and internal sphincter ani, and the levator ani muscles, the ischio-perineal ligament, the jjosterior part of the superficial and deej) fascia, the anal fascia, and adipose tissue. It is covered below by the skin, Fig. i6. — Dissection ol the Muscles of the Perineum and Pelvic Floor. A. Anus ; li. liulb of the V.igina ; C. Coccyx ; I,. Larger sacrosciatic ligament ; P. I'ernical body ; U. Urethra ; V. V.igina ; Ci. Vnlvo-vaginal gland, i. Clitoris; 2. Its suspensory ligament ; j. Crura clitoridis ; 4. Krector clitoridis muscle ; 5. Constrictor cunni ; 7. Transversus perinei ; 8. Sphincter ani ext.; 9, 10. Levator ani; 11. Coccygeus ; 12. Obturatorjext. 40 MEDICAL AND SURGICAL OYNiECOLOOY. bohiiul by tho mucous mombrano of tie rectum, nnd nbovo nnd in front by tho mucous mombrnno of tho vulvn nnd Homotimes of the vaginn. This body is of great importance by forming the centre of tho whole perineal region, and by its muscles, fascia, and ligaments being fast- ened to the surrounding bones, it bo- comes the chief support of tho whole pelvic floor. The blood supphj by means of tho internal pudic artery is distributed the same as in the male. The nerve sui)ply is distributed from the pudic branches Fu;. 17.-Trianguiar.si1.-1pe of the sacral plexus and from tho of perineal body. pudendal branchos of tho small sciatic. Tho lymphatics lead to the inguinal glands. CHAPTER IV. GYNAECOLOGICAL TECHNIQUE. The number who do not believe it necv?ssar to observe stringent precautions in operative surgery is fortunately very small, and is diminishing every day. The study of bacteriology has placed surgical operations on a thorough basis. Every surgeon must have a true conception of the terms sepsis, asepsis, and antisepsis, and determine nt nil costs to apjily his knowledge prac- tically to his everyday work, and in order that he may have a knowledge of the one, and be able to carry out the other, presujiposes n thorough trnining in the principles of bacteriology at least. The scientific application of an aseptic and antiseptic technique can be thoroughly carried out only by observing every detail, even the most minute, the utility of which has been proved by bacteriological research. It is necessary to keep before one's mind an GYNiECOLOaiCAL TECHNIQUE. 41 cxaltfd idvii of surgical cloaiilinoHH, rtMin'mbfrinK tlmt ns a chain is no Htron^i'r than its weakest link, ho aHeptio 8ur^'ory is only so far aseptic ns the weakest link in its chain. Sucei^ss doc^s not apply alone to the Huceessful termination of larj^e or extiMisive operations, but it ai)plies e<iually to the lesser details of obstetrical as well ns gynteeoU)^ical work. In these as well as in the formor, without that ri^'id attention to surgical cleaidiness, success cannot be expected to follow, but on the contrary, both patient and surgeon mny expect to be doomed to disnp- pointment. The term sepsis or septic infection includes nearly all the surgical infections, general or local, resulting from bacterial invasion. The symptoms as a rule are due not so much to tluH bacteria themselves but to their chemical products. When the bacteria have gained entrance into the general circulation and have multiplied there, the system becomes more or less overwhelmed with the bacterial poisons and that condition is called acute sc pi icivmia. Localization of the pyogenic bacteria in the organs give rise to multiple abscess formation, and that condition is called puivmia. The phenomena resulting from the absorption into the circulation of the products resulting from the local growth of putrefactive micro- organisms are included under the term sapnvmid, while the nbsori)tion into the circulation of tlie products result- ing from the local action of infective organisms, consti- tutes an infective toxicmia. General septicaemia or pyjBmia mny be set up by almost any of the micro-organisms which have pyogenic i^roperties, but the most frequently met with in surgical work are the staphylococcus pijofjoies aureus; the streptococcus pyogenes; and the bacillus colt communis. Less frequently we have the stttphylococcus cpidermidis alhus or the staphylococcus pyogenes alhus; the staphylococcus pyogenes citreus; the gonococcus of Neisser; the bacillus pyocyaneus, or the bacillus of green 42 MEDICAL AND BUROKJAL OYNiEUOLOOY. puH; nnd the niicrococrus lanrcohttmi, or (llplorncms Itnciniioiiio'. The i)riiicii)al iiiicTo-or^niiiiunH coticfriu'd in sup- puration are the micro-cocci (Gk. kokkos, a keruol), a Hinall round body. The staph i/loroccus (Gk. staph iilos, a bunch of grapi^H) }>!l<HI<')U's aureus, in more common tlmn any other. It may be hIiowu on the skin, in the secretion of the mouth, beneath the finder nails, in water, in the air, and else- wlu>re. In culture media it forms iarj^e j^olden y(>llow nuisses. It is the most frequent cause of superficial and deep abscesses, nnd it lias often b^^en recognized as the infectious agent in general septicjemia following operations or child-birth. The other varieties of staphylococci, namely, the staphylococcus (^pi(h>rmidis albus, and the staphylococcus pyogenes citreus, differ little from the fore- going, except as their names imply. The staphylococcus epidermidis albus being, for instance, found very abundant on the skin even under normal conditions. The streptococcus pijof/enes grows in chains (Gk. strej)tos, a chain) consisting of from four to ten or more cocci. External inflammations due to streptococci are characterized by their spreading character and erysipela- tous redness. It is one of the most frequent causes of post-operative peritonitis; the pseudo-membranous anginas of scarlet fever and measles are, as a rule, due to it, and there is a strong connection between it and the different forms of liuerperal infection. The Gonococcus. Much pathological imjoortance has been attached to this organism, and it undoubtedly plays an important part in the inflammations of the tubes and ovaries. The (liplococcus pneumonic^ is the causative factor in acute lobar pneumonia, but it is also known to be a definite pus-producer and has been found in acute abscesses, in empycBma, in suppurative c litis media, in quinsy, and is OYN-EC;<)L()OICAL TE(!1INIQIIE. 43 not Hii uncomiuon cause of puerperal and sejitic wound infections. The hdcilliiH voli rommiuiin is constantly present in the fjuces of man and is more oft<Mi than any other tlu^ cause of acut(> KUpi)urative p(>ritonitiH, especially wln^e there has betui an opening between the lumen of tlie bowel and the peritoncfd (ravity. In practising asepsis w(> aim at bringing about the com- plete absence of septic material, a condition in its entirety impossible. Most fresh wounds contain a certain number of organisms even under a strict aseptic technicpie, but either tlu^y are non-virulent or present in too small num- bers to givi' rise to the phenomenon of sepsis, finding the surroundings inimical to growth and multiplication, or they are destroyed completely by the natural protective powcTs of the body tissues. The maintenance of an aseptic condition is certainly a most important point to be aimed at in forvnulating a techni(iue, and when formulated it must not app'y alone to surgical operations, but to every detail of minor work in which a lesion in the mucous or serous membranes or in the skin may permit of the introduction of such micro- organisms. In practising nHfisrpi^is we employ the various means which have been devised for destroying bacteria or in- hibiting their action, and the agents employed to bring about this condition are called (mtiscptirs. Sterilization. Bj' lixis term is meant the process which brings about the absolute and complete destruction of bacteria. The ngpnts chiefly used for the purpose are heat, (Irij and moist, and rhrmicdl (fisinfcvfion. For carrying out sterilization by means of drji had a hot air sterilizer is required, and to destroy the ordinary non-spore bacteria requires their exposure to dry heat at a temperature of 100° C. for an hour and a half, and where spores exist, at a temperature of 140°C. for three hours. ■l:..^ 44 MEDICAL AND SURGICAL GYNECOLOGY. Unfortunntoly the procoss at that ti>mi)ornture will dcHtroy many substances of vegetable^, or animal orij^in, and the metliod has consec^uently been sui)planted by more sptH^dy and less risky methods. Hfrrilization htj vioi'st hcaf. Boiling water is one of the quickest agents which we jiossess; ijyogenic cocci and other vegetative bacteria, are destroyed in from one to five seconds, while anthrax spores succumb in two minutes. Sterilization hij }<f('(nn is another simple and practical mc^thod. Several kinds of steam sterilizers have been recommended, one of the cheapest and most convenient being the copper sterilizer of Arnold. One of th^ most ingenious methods of ensuring comjjleto disinfection is that known as fractional or (liscontinuons sterilization. It consists in keei^ing the fluid to be sterilized in a steam sterilizer at a temperature of 1(X)°C. for twenty minutes on three successive days. By this means any spores which e8cai)e destruction at tlie first heating will have grown out into vegetative forms and will be killed by the second heating. If the process be repeated for a third time, one can be reasonably sure of a completely sterile fluid. Steam sterilization is however not ai)plicable to all objects to be sterilized, as for instance, the hands of the operator, his assistrait, or the part of the patient to bo operated upon. For them chemieal disinfection is required. The ideal chemical disinfection is one that demands a host of qualifications, and when judged by such a standard, no single one fills the requirements. Carbolic acid is a powerful antiseptic but a dangerous one. Besides being an antiseptic it is also a deodorant and local ansesthetic. Corrosive sublimate. The extreme toxicity of this chemical is well known and some deaths have been directly traced to its use. It has a strong germicidal power, but not absolutely so, besides experiments have definitely provetl that even in weak solutions it injures fresh wounds, GYNiECOLOGICAL TECHNIQUE. 46 producing when examined under the microscope n distinct line of superficial necrosis. Potdssiiiin p('rm(ni(j(()i(itr, in solutions varying in strength from 1 to 10() to 1 to 10, possesses some germici- dal power. Other chemical disinfectants such as boric (icUl, iKiptliol, and salicylic acid are of questionable usefulness. Tlie day has come • en the use of antiseptics must be rele^gated to the period before operation, and reliance placed during operation in the maintenance of an asei)tic condition. THE PRACTICAL APPLICATION OF SURGICAL ASEPSIS. Under all circumstances personal hygienic measures are (essential, both as to the condition of the whole body as well as that of the general clothing. It is best to be provided with an operating sidt after some approved plan and so constructed as to leave the arms bare. The suit, previously sterilized, can be slipped on after the removal of the outer clothing and before the commencement of the operation. Not only must the operator and his assistants be thorough in the cicaiisiny of the hands, but all those who in any way aid in the handling of the materials employed during the operation. For this purpose Hunter Robb recommends that the hands and arms be vigorously scrubbed with green soap and water for ten minutes, the water used being as hot as can be borne, and changed ten times. They are then to be immersed for two minutes ia a warm solution of permanganate of potassium; next they are to be washed in a warm solution of oxalic acid; next rinsed in sterilized lime water; next in sterilized normal salt solution; and finally immersed in a 1 to 500 solution of bichloride of mercury. Just before beginning the operation, the hands should be rinsed in sterile salt solution to rtMuove any excess of bichloride. The use of the permanganate and oxalic solutions have either never been used or have been abandoned by many good surgeons as affording no additional safety. 46 MEDICAL AND SURGICAL GYNAECOLOGY. One of the newest methods employed for hand disin- fection is chlorine, produced by mixing household chlor- inated lime with crystallized carbonate of soda. Its chemical action is a little obscure, but it is virtually a production of the so-called chlorinated soda in a fresh and liquid state and is better known by the familiar name of Labarraque's solution. It is used in the following way : After thorough scrubbing with hot water and green soap, as already described, and the nails carefully cleaned, a small tablespoonful of the ordinary commercial chloride of lime or bleaching powder is put in the palm of the hand and on it is placed a crystal of carbonate of soda or common washing soda about one inch wide and lialf an inch thick (of a size that will permit it to be easily rubbed about like soap). A little water is now added to made a thick cream, and this is rubbed up and down the hands and arms, and well under the finger nails, until the little rough grains of chloride of lime disappear or markedly diminish, or until the creamy fluid thickens into a pasty mass. This pro- cedure should last about five minutes, after which the paste is washed oft' in sterile water. After the final wash- ing the hands will be found smooth, soft and smelling of chlorine. If the odor persists after the operation it may be removed by washing in a one-fifth per cent, solution of aqua ammonia. Its efficiency cannot be doubted, for out of forty-two tests made according to the foregoing method, forty gave sterile results. It is advisable to have a patient who is to undergo some very serious operation, such as an abdominal section, in bed and under observation for a few days prior to oper- ation. Light nourishing food should be given until the last twenty-four hours, when the diet is to be restricted to milk or broths. The bowels should be moved daily, and on the night before the operation a purge should be given, followed the next morning by a rectal enema. GYNECOLOGICAL TECHNIQUE. 47 The field of operafinn may be rendered prncticnlly sterile by the following procedures, supposing it to be a section : (1) A bath of soap and water and a vaginal douche daily for three days. (2) On the evening before operation the abdomen and pubes are shaved. (3) The parts thoroughly scrubbed with soap and water, then with ether, and then with bichloride of mercury (1 to 1000). (4) A compress of bichloride (1 to 1000) is afterwards to be applied, and kept there until the patient is brought to the operating table. After being antesthetized and placed on the table, the field of operation is again scrubbed with alcohol or ether, next with bichloride (1 to 1000), and finally irrigated with sterile salt solution. Trivial operations upon the uterus or vagina should be carried out with the same due regard for the dangers of infection. On the evening preceding operation a cathartic is given; the external genitals are cleared of hair and scrubbed after the manner of the preparation of the abdomen, the vagina carefully douched with bichloride solution (1 to 5000), followed by sterile water, and the parts carefidly covered over with a large sterile occlusion pad. On the following morning a rectal enema is given, and after being anesthetized, the vagina is scrubbed with a sponge charged with green soap and water, and after irrigating to remove the excess of soap, it is washed with a warm solution of bichloride, and then with sterile salt solution. Instruments should be so constructed that they can be readily taken apart and cleaned, and of such material as to permit of easy sterilization. The method of Schimmel- busch is by far the most convenient and effective for general employment, and consists of boiling the instru- 48 MEDICAL AND SURGICAL CxYN^COLOGY. ments for five minutes in n one-per-cent. solution of carbonate of soda. Any ordinary dish will serve for the Ijurpose, but it is convenient to have a specially constructed apparatus of copper fitted with some sort of heating apparatus, if stationary, a Bunsen burner. A flat wire basket fitting into the boiler will facilitate the introduction and removal of the instruments. Trays made of thick glass are the most satisfactory vessels in which to keep the instruments at the time of operation. By the use of hot water or steam they are apt to be broken, brt they may be rendered sterile by first washing them thoroughly with water and then filling them to the brjm with, or immersing them in a solution of bichloride (1 to 500), in which they are allowed to remain for an hour. Just before being used they are washed out with sterile water' and filled with enough of the same to cover the instruments. In the choice of sutures and ligatures certain points must be taken into consideration. No suture material will suffice for all purposes, but whatever is iised the main points to be considered are, that it must be sterile, smooth and pliable, but not brittle. The substances commonly employed are surgeon's cable twist silk, numbers 1, 2, 3, 4 and 5; silk worm gut, fine and coarse; kangaroo tendon; and catgut, sizes A, B, C, D and E. For the preparation of silk lufdturcs or siitHvcs, each size after being cut in appropriate lengths are wound on sejDarate glass reels. On one reel there should be at least four heavy ligatures, three feet long; on the second, ten intermediate or deep ligatures, eighteen inches long; on a third, ten smaller for superficial ligatures, eighteen inches long; and on a fourth, ten small, also eighteen inches long, for fine sutures. The four reels after being put into an ignition tube and the moutii plugged with cotton batten, are sterilized in an Arnold steam sterilizer for one hour the first day and for half an hour on each of GYNAECOLOGICAL TECHNIQUE. 49 the two succeeding days. Tlie tubes so prepared may be kept in glass jars, but for safety it is best to re sterilize what may be required immediately before every operation. Silk-worm (jut is a substance admirably adapted for suture material. It is smooth, easily introduced, is non- absorbable, and resists the invasion of bacteria much better than silk or catgut. In preparing it for use, the twisted ends of the strands being cut off, eighteen of them are folded once and placed in a glass tube in which they are to be kept. They are then sterilize.l after the manner described for the sterilization of silk ligatures. Cdffiut is, in many ways, the ideal material for sutures, but unfortunately there is no method of rendering it absolutely sterile. Notwithstanding the most careful preparation, suppuration sometimes follows its use. Many well known surgeons, having sufficient confidence in their methods of sterilizaticm, use it not oidy for sutures but for small and even large i)edicles. The following are a few of the most reliable methods for its preparation: (1) The raw material is placed in ether for seventy-two hours; next in an aqueous solution of bichloride of mercury (1 to 1000) for twenty-four hours; next in oil of juniper for forty-eight hours; after which it is to be transferred to absolute alcohol. (2) After being in ether for twenty-four hours, it is transferred to a solution of bichloride (1 to 100) in eighty per cent, alcohol, and changed daily for three days; after- wards it is preserved in absolute alcohol. (3) After being soaked in ether for twenty-four hours it is wound in three feet lengths on reels, and jjlaced in botth^s plugged with cotton batting. The bottles are then placed in a water bath and heat gently applied until the alcohol boils for five minutes. The boiling process is repeated for three days after the method of fractional sterilization. 50 MEDICAL AND SURGICAL GYNyECOLOOY. (4) The catgut is put in ether for a j^e. od of from two to seven days, according to tlie size of the gut, the ether being changed once. It is then transferred to a solution of bichloride in alcohol (1 to 500) for from two to seven days, after which it is i)reserved in a solution made by dissolving two ounces of iodoform in four ounces each of alcohol and ether. (5) Five volumes of the formal of commerce with from forty to one hundred volumes of formaldehyde are turned into one hundred volumes of distiiieJ water. The threads to be sterilized are placed in a small i^ask in a glass and filled with the solution until the mouth cf the flask is im- mersed, the top of the glass being protected with filter paper moistened in a solution of formalin (5 to 100). It is kept at the temperature of the room for twenty-four hours. The formal is re^jlaced by alocliol, which dissolves the little formalin remaining, and after decanting again the flask is filled with alcohol and covered with the formalin filter paper. This method is advantageous as it requires no apparatus, no heat, no difficult manipulation and is applicable to all ligatures, catgut, silk, hair and rubber material. (6) Modified Kroniij method. 1. Roll the catgut, twelve strands, in a figure-of-eight form so that it can be slipped into a test tube. 2. Bring the tube up to a tem- perature of 80° C. and hold it at that point for an hour. 3. Place in cumol which must not be above 100° C, raise it to 165° C. and hold at that point for one hour. 4. Pour off the cumol and either allow the heat of the sand bath to dry the catgut or transfer to a hot-air oven at a tem- perature of 100° C. for two hours. 5. Transfer the rings with sterile forceps to the test tubes previously sterilized. In drying or boiling the catgut it should not come in con- tact with the bottom or sides of the vessel, but should be suspended or placed upon cotton loosely packed in the bottom of the beaker glass. GYNiECOLOGICAL TECHNIQUE. 61 On the part of some surgeons there is nn nnxiety felt lest the life-time of the catgut may not be sufficient to accomplish the objects for which it was used. If absorbed too soon, there is a fear of recurrent hemorrhage or gaping of an incompletely healed wound. To overcome this difficulty various methods have been adopted for hardening it, the principal agents being chromic acid and bichromate of potash. The catgut is, as usual, soaked in ether for twenty-four hours; it is then placed in a one-per-cent aqueous solution of chromic acid for from twelve to twenty-four hours, according to the density required; next in a fifty-per-cent solution of sulphurous acid for twenty-four hours; next in an alcoholic solution of bichloride (1 to 5(X)) for twelve hours, after which it is preserved in absolute alcohol. Kan(f(iro() tendon possesses many excellent qualifica- tions. It is smooth, pliable, strong, and not too readily absorbed, from eight to ten weeks being usually required for its disappearance. After being treated according to one of the methods described for the preparation of catgut, it is preserved in a solution of carbolic acid in oil (1 to 20). When re(iuired, the necessary number are removed with aseptic forceps, placed momentarily in ether to remove the oil, then wrapped in a sterile towel saturated with hot bichloride solution until they are used, when they will be found clean and soft. Dressings. When a wound is not to be closed hermet- ically it is important to apply a dressing which, while being free from pathological bacteria, will prevent the advent of micro-organisms fiom the outside and at the same time absorb the secretions from the wound and jjre- vent their subsequent decomposition. There is upon the market to-day an abundance of what is known as "anti- septic dressings" and "gauzes" which are often of great utility in the management of wounds when the surrounding circumstances and conditions render their use necessary. 52 MEDICAL AND SURGICAL GYNECOLOGY. Good (ihsorhmt cotton in rolls and common chfesc cloth will suffice for nil ordinary surgical dressings. The cheese cloth may be prepared by cutting it in lengths of two yards and boiling for half an hour in a one-per-cent. solu- tion of carbonate of soda, and then rinsed in sterile water and rolled up. Atmovtwnt cotton, (jauzcs and l)(in(l<i(/cs, wrapped in towels, may be sterilized by exposure fo" three- quarters of an hour to the steam of an Arnold sterilizer, after which, if not rolled or packed too tightly, may be considered absolutely sterile. Iodoform (jonzc is occas- ionally required for various purposes. The gauze, made ready after the manner already described, is immersed in an iodoform mixture, prepared by mixing enough castile soap with twelve ounces of a one-per-cent. aqueous solu- tion of carbolic acid to make good suds, after which fourteen drachms of iodoform are added and thoroughly mixed. Pernio n<j(m(ttc (jduze is not unfrequently used for dressings, having no objectionable odor in itself and has the power of diminishing the odor of foul smelling discharges. It is prepared by saturating sterilized gauze with a one-per-cent. aqueous solution of permanganate of potash. Sponges. Either the ordinary marine sponges or substitutes made from sterilized gauze are the ones chiefly used. Marine sponges are more elastic and pliabl(> than any other material, but unfortunately they cannot be sterilized by steam without ruining them, and other methods do not always render them absolutely sterile. They may be prepared by first pounding them in a muslin bag to remove all particles of sand and then rinsed in several changes of water. If so desired they may now be bleached by placing them for twenty minutes in a warm solution of ijermanganate of potash (half a drachm to two pints of water). After being rinsed in warm water they are them immersed in a warm solution of hj posulphite of .soda (one and a half ounces to two pints of water), to GYNJICOLOOICAL TECHNIQUE. 53 wliich Imlf an ounce of hydrochloric acid hos Just hern (i(l(l('(L and allowed to remain in it until (initc white. After bein^f thorou^'hly Hoaked in water they are next plaet'd in a bichloridi^ wolution (1 to 5(X)) for twelvH- liourH, and after bein^ again washed in sterile water they are transferred to glass jars containing a three-per-cent. solu- tion of carbolic acid. Gauze sp(ni<ics may be made by wrapping absorbent cotton somewhat loosely in squares of gauze, the corners bcung brought together at the top and tied with a thread, or they may be allowed to remain tlat, the edges biung folded under and hemmed. Drainage. A few years ago nearly ninety per cent, of all cases of abdominal section were drained, now not more than ten per cent, are drained, but as it is yet indispen- sable it is necessary to decide ui)on the safest and best means. Where tubes are emi)loyt'(l those made of glass are the best as they can be readily sterilized. When drainage is absolutely necessary, as in cases of wide spread injury to the cellular tissue of the j)elvis and it is impos- sible to check the bleeding, or in cases where a cavity has been opened, the walls of which can not be entirely eradicated, or in cases where the pelvis has become in- fected by the rupture, accidental or otherwise, of a puru- lent formation, the ordinary glass drainage tube has been supplanted by iodoform gauze. To make it most effectual, the gauze is pushed down to the bottom of the cavity, either inserted in a sausage-shaped bag or in long strips placed in position by the aid of dressing forceps or sponge holders, the free ends being brought to the outside through the abdominal wound or through the vagina, should the pelvic cavity be opened through that route, or drainage by that route desirable. Irrigating fluids. The routine treatment of irrigation of the pelvic cavity in every case cannot now be considered a necessary i)ractice. Where the structures are non- adherent and there have been no special complications, 5-4 MEDICAL AND SUmUCAL OYN.FX'OLOGY. thoro would hihmii to bi^ no indication for itH (Mni)lovnu>nt, but lifter till' romovnl of a mass whii'li coutains bloody fluid, or whi>re there has been a ^reat deal of oozing, irrij^ation may sometimes be useful. If the fluid whii^li has escaped be of a septic nature, irrigation is more likely to spread it further between the coils of the intestines than to remove it. In selectiiifif a fluid, it is necessary to endeavor to secure one that will ^ive the best results with a minimum amount of harm. The fluid most generally used is plain water rendered sterile by boiling and when r'^quired for irrigation may readily be brought to the required tem- perature, 105° F., by having two vessels, one containing hot and the other cold water. The jirinciiwl objection to its ase is that it has a definite deleterious effect upon the tissues, and to overcome this difficulty, nornud salt sol lit ion is extensively used. It is so prepared as to correspond very closely in specific gravity with the normal serum of the blood. Common salt, in the proportion of forty-five grains to the pint, is dissolved in sterile water, and after being put in sterile flasks and plugged with cotton is sterilized by fractional sterilization. Before operation, two flasks are re-sterilized and one is kept hot while the other is allowed to cool, and when they are required they are mixed to the proper temperature in a graduated jar containing a thermometer. The use of strong antiseptic solutions, such as bichloride of mercury and carbolic acid, must be unhesi- tatingly condemned, and in the use of mild ones, such as boric and Thiersch's solutions, it may be said that they possess no advantages over the ordinary sterile water or salt solution. Some form of dry powder is frequently used to dust over the abdominal wound or after plastic operations, and the ones most in use are boric and iodoform powders. The penetrating odor of iodoform is a strong objection to GYNJICOLOGICAL TECHNIQU— 55 it, nncl it is not to bo forgotten that somo pnticntH nro t'xtnMnc^ly HUH(H'ptiblo to its toxic efftn^ts, but on the other hand it in the best germicidal powdc^r in UHe. A coinbiiia- tiou of iodoform one part and boric acid wevon parts in an excellent mixture, having the advantage of being non- irritating to the skin as pure iodoform sometimes is. INSTRUMENT LISTS. It is important to write out lists of the instruments that are used in different operations and to keep them where they can easily be consulted. INSTRUMENTS FOK AN ABDOMINAL SECTION. A8[)itiitor. Nozzles. Catheters. Retractors, large. Cautery (l'u<iueliii). " next size smaller. Forceps, long dressing. Kubber tubing for [jedicle. " long liii-mostatic. Rubber tubing. " medium liii'mostatic. Scali)el8. •• small hiumostatic. Scissors, long. " bullet. •' short. " rut-tooth. Sound, uterine. Drainage tubes. S(»eculum, Sim's. Irrigator. Sponge-holders. Needles, large. Tenaculum, straight. " transfixion, right curved. " curved. " " left curved. Trocars, large and small. " " straight. Two Ntilaton's forceps. Needle- holder. INSTKUMENTH FOR VAGINAL HYSTERECTOMY. Catheter, glass. Needles, transfixion, straight. Curettes, dull and sharp. Needle-holder. Forceps, dissecting. Retractors. " lonp^ hit'mo8t«tic. Sealjiels. •' medium hamostatic. Scissors, long and sliarp-pointed. " small hii-mostatic. Sj)eculun», Simon's, with handles •' bullet. and four blades. Needles, curved, large, medium Sound, uterine, and small. Sponge-holders. Needles, transfixion, right curved. Tenaculum, straight. INSTRUMENTS FOR PERINEORRHAPHY. Catheter. Retractor, small. Forceps, hivmostatic. Scalpels. " long dressing. Scissors, right-angled, bullet. " left-angled. " rat-tooth. " straight-pointed. Needles. Sound, uterine. Needle-holders. Tenacula. Nozzle, glass. 56 MEDICAL AND «U1UHC!AL (lYN/ECDLOGY. Ciithotor. Cui'ulluH, (lull and Hhnip. Diliitoi'H, (litl'ureiit HJ/es. ForoepH, liiiiiioHtutic. " It'll^f < I I'OHhI !!{:;. *' rat-tooth (lre88iiig. bullet. Irriyiitor. NeocUes, asHorted HJzeH. IN8TRIIMKNT8 FOR TBAOHKLORKHAPIIY. Neodlo-lioldei'M. Noz/.lo, j^laBH. Retractor, Hiiiall. Scalpels. HcJHHorH, Htraifflit and curved. Bound, uterine. S|>eoulinn, Sim's, or Simon's with haiulleH and four blades. Tenacula. INSTRUMENTS KOR DILATATION OK CERVIX AND CURETTINCJ OK UTERUS. Catheters. Catheter, irrigatinj^ two-way. Curettes, sharp and blunt. Dilators, three sizes. Forcei)s, bullet. " long dressing. Forceps, rat-tooth. Nozzles, glass. Sound, uterine. SjHiculum, Sims's, or Simon's with handles and four blades. Tenaculum. LIST FOR ABDOMINAL OI'KRATIONS OUTSIDE OK HOSPITAL. Aspirator. Instruments in bags. Basins for instrument*. Cautery (Piuiuelin). Coats for doctors and nurses. Solutions : bichloride (1 to 20). " crude carbolic acid. " normal salt. Crystals of permanganate of potas- sium and oxalic acid. Soap and two brushes. Rubber sheets and ovariotomy pad. Sterilized towels. Ether and cone. Chloroform and inhaler. Hypodermic syringe. Brandy. Strychnine tablets (,5'j grain). Rubber tubing. Si)onge8. Silk ligatures, four sizes (.3 tubes). Catgut ligatures, three or four sizes. Silkworm-gut. Scultetus bandage. Safety-pins. Sterilized gauze. Strips of gauze for dressing. Celloidin. Sterilized cotton. Iodoform gauze. Iodoform and boric acid powder. Glass graduate. LIST FOR PERINEAL AND OTHER MINOR OrEKATIONS. Instruments. Leg- holder. Ligatures. Sterilized stockings. Perineal pad. Douche bag. Dressings. Bandages. Cotton pledgets. .ETIOLOGY IN (lENEUAL. 57 CHAPTER V. .ETIOLOGY IN gi:ni:ral. The causes of the diseases of women arc niniiily Httributnbl(> to tlio orrors, (lir(>ot or indirect, of modi^rn life. Tlioy may be tlius clnssifi'/d: 1. Abnormalities produced by hereditary congenital deficiencies of development. Tho dofectivo heredity is probably not generally immediate but a gradual deeleunioii, for tlie most part on the maternal side, tending, by continuous de^eni*ration, to induce in the progeny feeble sexual formation. For instance, the first stage may be found in a woman having a uterus of moderate development, but contracted at its opening, and which becomes lacerated in her first confinement. The offspring, possessing a feebly developed uterus, becomes pregnant by chance, it may be long after marriage or after an operation; or she may have a congenitally contracted upper vagina ; or a tendency to infantile pelvis, with absence of sexual appetite. She becomes the mother of one child who has yet a feebler unimpregnable uterus, with atrophic ovaries and deficient and most likely pain- ful catamenial discharge. 2. Abnormalities produced by congenital or sub- sequent arrest of development owing to the effects of bacterial action. The eruptive fevers, as measles, scarlet fever, small-pox and probably syphilis also, by the action of their toxines, directly conveyed to the embryo by absorption from the maternal blood, destro_y the vitality and power of growth of the germinal genital cells. After birth and at any time previous to fail development, these causes and, along with them tubercalcsis, may effect and destroy the vitality of the growing cells. The destruction of vital force in the special germ cells produces arrest of development, and as a result congenital deficiencies and arrest of development are found ,in the pvaries, oviducts. 58 MEDICAL AND SUR'ilCAL GYNJICOLOGY. uterus, vaj.^ina, hymen, or vulva. Should the development of the genital ridge be deficient or arrested, the ovaries are so undeveloixnl that they are unable to arrive at their successive montldy maturity, whence arise amenorrhosi and sterility. If the growth of the upper part of the Mullerian ducts ceases, the oviducts are minute or defective, By the absence of fusion, complete or pat-tial, of tlu^ two Mullerian ducts in the genital cord, the uterus is double or bifid. From arrest in one duct and development in the other, the unicorn uterus results, and, after the normal fusion, cessation of vital growth may (^ause the uterus to be diminutive. In a similar manner there may bo two vaginae, or one defective in size, or no vagina at all. A uterus, normal in length, but with feeble develop- ment and deficient in strength, may have a feeble cervico- corporeal junction and which, as a result, Ik likely to fall and be converted into the position of anteflexion. Coincident with this there is usually dericiency in the size of the opening. Owing to such a condition, the secretions collect within the cavity, are diflScult to expel, and as a result there will arise cervicitis and dysmenorrhcea. In a strong uterus, with a deficiently developed os, there is liability to laceration at parturition, and if the laceration bo double, e\ersion of tlie lips and grarular erosion nre likely to follow. If the fresh raw surfaces of a laceration absorb septic germs, pelvic cellulitis results. Should the perineum be deficient in development or rigid, laceration of it is likely to take place, and when septic infection occurs in connection with a lacerated cer\ ix, subinvolution of all the genital structures, as a rule, res ilts. With subinvolution comes the various forms of uterine misplacements. With subinvolution and misplacement, aided by special mic- robes, as those of gonorrhoea or of the imerperal septic infections, comes endometritis. With its extension to the tubal mucous membrane, comes salpingitis and ultimately by overflow of its contents through the fimbriated ex- .ETIOLOGY IN GENERAL. 59 tromity, arises localized peritonitis or abscess formation. Thickening of the tunic of the ovary succeeds local inrtanimatory action and, as a consequence, there follows painful ovulation and various forms of degenerative changes in the ovaries. 3. Hereditary constitutional defects in which certain classes of cells morbidly proliferate forming tumors. Tlie aetiology of the dermoid tumors is attributable to the origin and mode of development of the ovfry. From the mesothelial di ision of the mesoderm the ovary is formed. The mesothelial layer of the mesoderm is closely connected with the ectoderm. From the ectoderm are developed the epidermis and epidermal structures, such as hair, nails, glands, the eye, and the mouth cavity with the teeth, all of which structures are occasionally found in the dermoid cyst. Thus, in the formation of the dermoid ovum, some ectodermal cells have by inclusion been incorporated with the mesothelinl layers and, continuing to grow, produce a cystic tumor with skin-like walls and containing any or all of the structures formed by the ectodermal layers. The pdrororian cijst is caused by an embryonic deficiency of absorption and a subsequent hypertrophic glandular secretory development of the cylindrical lining cells which normally remain quiescent in the sexual part of the female rudimentary Wolffian ducts, sitrated in the connective tissue of the broad ligaments, and known as the parovarium. As to the n3tiology of ovdrian cystomo, in the develop- ment of the ovary, portions of its germinal epithelium grow inward and some of the cells become ova while deeper multiple cells of the same description form the membrana granulosa. The i)ormal function of these cells is to conduce to the nutrition and further development of the ovum. It occasionally happens that the tendency to continuous proliferation of the cells of this layer is greater than required and there is multiplication in excess. At 60 MEDICAL AND SURGICAL GYN/ECOLOGY. the snme time the inner cells rujituro nnd pour their secretion internally Jirul by such continuous process an ovarian cystoma is formed which persistently enlarges. The degeneration being of a type which effects the develoi)ment of all the cells of Ihis class, the disease does not attack one follicle alone, but is common to all; hence the cystoma, on its attainment of some size, is almost always multilocular. Mijowa, which is a proliferation of unstriated muscle fibres enclosed in a connective tissue capsule and usually multiple, is attributable to absence of pregnancy, from whatever cause, in a woman of strong sexual development. Carcinoma or cancer, which is a continuous cell pro- liferation, of epithelial type, invading the lymi:)hatic spaces and vessels and always originating in epithelium derived from the ectoderm or entoderm, has its cause in such sites and conditions as induce excessive formation of cells of degenerating quality. Such sites and conditions are exceedingly common in the chronic granular hyperplastic face of the lacerated cervix. Continued irritation from any cause, for instance of a myoma, may prodv ce a constant proliferation of a primary or embryonic type in the connective tissue and, as a result, a sarcoma of the round or spindle celled variety is produced. 4. The training and effects of education. The long confinement in-doors during school hours, frequently with impure air; the absence of exercise of arms and legs, tending to stagnation of circulation; the stooping posture; the increased attraction of blood to the brain and great call upon the mental powers; improper exercise; the personal competitions culminating in place examination; all have their deleterious effect and tend to develop mental at the expense of physical power, and producing as well, constipation, auiemia, irritable hypersensitive nerves and derangement of the menstrual function. iETIOLOGY IN GENERAL. 61 5. Personal habits. That care, so necessary at each menstrual epocli, is not as scrupulously observed as it should be, and at times injurious consequences, of a tem- porary or permanent nature, result. Of all the injurious influences to which is attributable the great mass of disease now so prevalent, the greatest is the custom of the alteration of the form of the body and of the position and relations of the internal organs by compression of the lower thorax and abdomc^n, by means of corsets. The influence is markedly accentuated by the attacliment of the skirts and petticoats around the waist and abdomen. In pregnancy the corsets are often worn tight so as to conceal the condition. Society often demands the ex- posure of the neck, arms and should(>irs to the suddenly varying temperatures of heated ball-rooms, corridors, verandahs, and gardens, while closely associated with these are, improper diet, irregular meals and late hours. The influences of absence of marriage, of late marriag(\ and of ineffective marriage, which includes artificial pre- vention of pregnancy, are highly deleterious. (). Sexual exhaustion arising from an insatiable sexual appetite, leads to (h^bility, to weakened nervous system, and chronic congestion resulting in endometritis. 7. Infectious diseases. Tlie effects of syphilis are seen in hereditary congenital and in simjjle forms. In the fornu^r, malformations are present at birth; in the latter the results, similarly causfMl, may not manifest themselves for varying periods after birth. The mother may directly transmit measles, scarlet-fevci, find small-pox to the f(t)tus. To gonorrhoea is to be ascribed a series of progressive diseases, which are as liable to be as virulent as they are continuous. Septicannia, induced primarily by the en- trance into the system throxigh the blood vessels or lymphatics of micro-organisms, may, if it does not prove at once fatal, produce wide spread damage. Tuberculosis in the geiutal organs may occur by the arrival of the 62 MEDICAL AND SURGICAL GYNECOLOGY. tubercle bncillus by the intestines, by the blood, or through the vnginn. 8. Lastly may be mentioned those diseases and con- ditions due to operative causes, niuong which may be mentioned the introduction of dirty instruments; the application of irritants; forcible dilatations; injections of fluids into the uterus; pessaries; exploratory jiunctures; and the improper treatment of abortion. CHAPTER VI. ANESTHETICS. The entire civilized world owes a countless debt of gratitude to Dr. W. T. G. Morton of Boston, the discoverer of the anesthetic properties of sulphuric other; and to Dr. James Y. Simpson of Edinburg. who, a year later, discovered chloroform. Much time has been consumed in discussing the relative merits and demerits of the two agents. The views of surgeons regarding their relative values vary widely, but there can be no doubt each of them has its advantages and disadvantages. In the administration of such powerful drugs, the fact must not be lost sight of, that they are not free from danger, and in the selection and administration o^ an anesthetic, the question of safety should dominate all others. Despite every precaution, and every care taken in their administration, sudden death occasionally will occur. For a long time chloroform was enthusiastically held in favour in this as well as in other countries, but it has gradually been supplanted by ether, on account of its greater safety. From statistics collected with the greatest care, it has been shown that the mortality from chloroform anresthesia is about one in five thousand, and that from ether, one in twenty thousand. From careful experiments ANAESTHETICS. 03 and observations it has been proved that chloroform exerts a steady, powerful, depressing influence on the heart, by its action on the heart mus o or its contained ganglia, and, consequently, a large number of deaths from chloroform are due to cardiac arrest. When chloroform paralyzes the respiration, it does so by its direct action ujjon the resi)iratory centre. The study of the action of ether on the circulation goes to prove that the primary influence of the drug is to stimulate both the vaso-motor centres and the heart. In etherization there is usually a pronounced rise of arterial pressure which is commonly maintained, even through a prolonged narcosis, and may continue after manifest failure of respiration. Fatal syncope, by the direct effect of chloroform upon the heart, is the common cause of chloroform death. On the other hand with ether, the direct effect of which is to stimulate the heart, death from syncope is rare. Notwithstanding the greater safety of ether, there are c{rciiiiisf(tu<'('s iDlti'cli nuHllftj flic choice of (tiKCfifhciics. Old people, where the chest has become rigid, do not seem to respond sufficiently to the demand made upon them by ether, but bear chloroform well. Ill obesity also, ether is often not well borne, producing much excdtement and rt^spiratory irritation, chloroform being often necessary to secure tranquility of breathing. In the presence of ovfjditic brain diseoses, including tumors, the dangers of aiuDsthesia are increased. Wide spread (dheroma should give to the surgeon, who desires anresthesia, much anxie'^^v, and when demanded, chloioform should be given the preference. In dif«'<ifies of the licart, ether is usually preferable to chloroform; indeed where the h(^art is very feeble, or the cardiac muscle degenerated, chloroform becomes a very dangerous remedy; and where orthoijnoia exists, its use is never justifiable. 84 MEDICAL AND SURGICAL GYNAECOLOGY. A mixture composed of nlcohol, one part; chloroform, two parts; nnd ether, three jmrts; commonly known as the A.C.E. mixture, if freshly mixed, may be chosen with advantage in cases of atheroma, obesity, and valvular disease of the heart. The local irritant effect of ether on the mucous mmnbrane of the air tubes contraindicates its use in extensive emphysema, in chronic bronchitis attended by expectoration, in dyspnoia, and in advanced pulmon- ary phthisis. In such cases, if anaesthesia is necessary, chloroform should be employed. In obstructive laryngeal disease or where there is contraction of the trachea, either from within or without, the greatest caution must be exercised, for the irritating effects of ether will increase the tendency to mechanical asphyxia. Both ether and chloro- form have a distil ct deleterous influence upon the kidncijs, but, of the two agents, etlier is the more dangerous. The great danger arises from swppressiou of urine and death from ura^.mia. There are L^iome jjatients who, although ai)parently healthy, liave sensitive bronchial mucous membranes, show a high rate of respiration in cither anjBsthesia, and cough, even in deep anjesthesia. In such cases chloroform should be at once substituted. Both before and during the administration of ether or chloroform, certain instructions should be rigidly kept in mind. 1. Analy7A> the urine, especially before the administra- tion of ether; also examine carefully the heart and lungs. 2. Examine the mouth for false teeth or foreign boditss. 3. Loosen the clothing to prevent constriction of the circulation or respiration. 4. Cause the patient to assume the dorsal decubitus, with the head resting low on a small pillow. 5. Anoint the face with vaseline to prevent irritation or excoriation. 6. Instruct the patient to close the eyes and to take deep, full and regular respirations. If excitement or a ANESTHETICS. 65 dread of danger occurs during the early inspirations, it is well to drop the mask and, in a few kind words, calm and encourage the patient. 7. Chloroform must be administered slowly and mixed always with a sufficient quantity of air. If ether is given, the precaution is unnecessary and may delay anitjsthesia, but in case of cyanosis, breatlis of pure air should be allowed until the cyanosis has disappeared. 8. Do not commence oi)eration until anresthesia is complete, indicated by paralysis of the palpebral reflex, and by relaxation of the voluntary muscles. 9. Secure good ventilation. 10. Watch carefully the pupils, dilatation or their failure to respond to light must be viewed as a sign of apprc )aching danger. 11. Watch carefully the pulse and respirations. Quick- ening of the respirations, as well as weak pulse or respira- tion, may denote that too much aiiffisthetic has been given. Loud stertor in chloroform anaesthesia is an alarming symptom, indicating epiglottidean closure of the larnyx. 12. Remove from time to time the mucous which is apt to accumulate in the mouth or throat by means of a small sponge on a holder. 13. Watch the color and expression of the face; lividity indicates asphyxia. 14. Allow no solid food for five hours at least before operation, nor should liquid food be allowi^d later than three hours. 15. Very nervous individuals should receive a hypoder- matic injection of a quarter of a grain of morphia twenty minutes before the ansBsthetic is commenced. All plans of administration now in use may be arranged under two headings: o^x'U (Khiiinisfration, which admits of the free access of air, and closed <«hnin- istration, in which the patient breathes out of and into a bag, with a more or less imperfect supply of air. 66 MEDICAL AND SUROIOAL GYNAECOLOGY. Open ethorizntion may bo prncticod by simply foldiiip^ ft towel ill the form of n coiio nnd puttiuj^tlio other iusido; or by making a cone of thick material which fits tightly to the face, at the apex of which a sponge is placed to receive the other. Allis' inhdler consists, essentially, of a series of folds of muslin on a wire frame-work and surroundcnl by a soft rubber cover. It allows the air to pass freely through, mixed with the ether, and, when properly used, does away with the sense of suffocation and the consequent struggles. Closed t^thorization is performed by means of an inhaler such as Clover's or Ormsby's, which are so constructed that the patient breathes in and out of a receptacle con- taining ether, the amount of air admitted being regulated by a stop-cock for that purpose. When ether is first administered, it should be small in amount and largely diluted with air, after which the air may be gradually withdrawn and the ether pushed more energetically. The patient passes through a stage of bewilderment, the face becoming flushed, the respirations rapid and the pulse accelerated. This is followed by one of excitement, which afterwards passes into a state of muscular relaxation. While administering ether, the fact must always bo borne in mind that its vapor commonly kills by asphyxia and not by syncope, henco, though the pulse is to be watched, the respirations should be the principal object of solici- tude, and tlu^ first appearance of dangerous symptoms should b(> met by prompt and suitable remedies. Chloroform may be administered by means of a towel placed over the patie^it's face, but it is best given on an Esmarch's mask, which consists of a wire skeleton covered with canton flannel. It fits loosely over the nose and mouth, thus admitting air freely, while the chloroform is dropped on it, a few droi)s at a time without its removal. After inhalation for a few minutes, consciousness is lost, the conjunctivae becomes insensitive, and the breathing AN-ESTHETICS. .67 assumes a somewhat stertorous character. Before com- plete aujusthesia, convulsive movements, accompanied with cj'anosis, often take place. It is best in such cases not to straggle with tlie patient, but to discontinue inhalation until the cyanosis has disappeared. During the entire period of administration, the finger should be kept over the temporal artery and the respirations watched. A patient may die, either on account of asphyxia or on account of heart failure, the latter being by far the most frequent cause. Failure of the pupils to respond to light, or tlieir wide dilatation is a sign of apijroaching danger. This, together with paleness of the face, biueness of the finger nails and a weak, tlickering pulse, should cause the anaesthetist to at once npply proper remedies. ^A^henever dangerous symptoms threaten, the aufes- thetic should be discontinued, either wholly or for a time at least. If the respirations become impaired or the pulse very weak, it may be possible to finish the operation with- out further administration. When the symptoms of resjairatory impediment do not yield promptly, place the fingers behind the angles of the lower jaw and force the jaw forward. If the breathing does not then promptly become normal, seize the tongue with forceps and pull it forward. If ordinary means do not suffice to restore breathing, resort must be had to (irtijiciiil rcspiratt'on, aided by lowering the lu^ad and elevating the body in a position similar to that of Trendelenberg. These efforts may be aided by flipping the chest with a wet towel or by the application of the poles of a Faradic battery, one polo over the phrenic nerve in the U'^ck and the other over the diaphragm. The question of the use of drugs in threat- ened accidents is a very important one. Hypodermatic injection of ether possesses no advantages, but rather, in cases of ether anresthesia, increases the difficulty. Alcohol in the shape of brandy or whiskey is an excellent stimu- 68 MEDICAL AND SURGICAL GYN.ECOLOGY. lant, but gives best results only when the cardiac failure results from hemorrhage or other surgical cause. The influence of hypodermatics of digitalis, or its alkaloid, is very pronounced, increasing the arterial pressure and the size of the individual pulse beats. Amyl nitrite, for which much has been claimed as a cardiac stimulant, has some effect in increasing the pulse wave, but it must be con- sidered as a doubtful remedy and used with great caution in anaesthetic syncope. The best results are obtained from the hypodermatic injection of strychnia. It causes a gradual rise of the arterial pressure and an immediate and extraordinary increase in the rate and depth of respiration. In order to get the best effect from the alkaloid it is essential to give it in large doses. To a robust individual, with serious anjBsthetic heart or respiratory failure, one- eighteenth of a grain may be given at once. CHAPTER VII. EXAMINATION IN GENERAL. GENERAL OUTLINES OF DIFFERENTIAL DIAGNOSIS. When a patient presents herself for advice and treatment, the first essential to a full understanding of her case, is a complete history. The subject naturally resolves itself into two parts, the history of the patient f. I the physienl examination. THE HISTORY OF THE PATIENT. The first interview between the patient and the doctor is an important one, and it is a very good rule to allow the patient time and oijportunity to state lier case fully. Not only what is said, but the manner in which it is said, will give the physician an insight into her dis- position and character and will enable him to treat her EXAMINATION IN GENEUAL. ()«.) mf)n> intclliKriitly mid succoHHfully. The iuv(>Hti^ation nuiy bt' codvciiii^iitly curried out by observing nnd mnking note of the t'ol lowing points. A printed form for ennt^-taking, while not esKential, is of great advantage. It Faves time and suggv sts objec^ts for incpiiry, wliieh n.ight bo overlooked, and, besides, is of gn^nt advantage in the subsequent study of the cases. FORM FOR CASE TAKING. Pkehknt Complaints and their Dukation, 1. Hixlory : Family Hi .story Previous Diseases First appearance Regularity Duration Amount and character Pain, before, during, or after Confined to bed Last appearance Date. Pregnancy, / At full term o 9! ' X ' In head In back In abdomen j^ In legs During coitus In sitting In standing ,In walking Labor. Puerperium. o n .Premature '^ g j Amount '■^ < [ Character ^ y I Persistence > £5 Duration Appetite Cause of illness (supposed by patient) 2. SlalUH PraneiiH : General Condition Condition of the Nervous System Constitution Breasts Urination Defecation Digestion Abdomen Vulva en Pi H E-c Position Size Mobility Shape Depth of Cavity '.Secretion 70 MliDlOAL AND SURGICAL GYN.RC'OLOOY. Pori Ileum I'HHJtioil Viiginii Kliape Uvoiu\ i^ipimeiits 'A IjtiuiitU TllhuM >, Density OvariuM «1 .Secretion DouffliiH' I'diich Internal ()« BIjk (lor Kxternal On Urethra ^Lacerateil liectiim Coinpli(;atioiis 3. Didiiuoiis : 4. Trtatmeut ami ProiirtiMs : The age of tlu^ pationt has a cliriHit b(>aring on many mattiTH. suoli as mrnHtruation and child-boaring, and will often throw much light on tho nature of the distiase. Cancor rarely occurs before the thirtieth or fortieth year, and more often about the time of the menopause. Social condition and occupation has often a material bearing upon the disease from which the patient suffers. It is of the utmost importance to know whether she sijends her time in sedentary pursuits, or, as a shop-girl, kept standing or walking about all day long; or, as a charwoman, whose daily round is one of severe toil <ind often hardship. Information as to whether the patient is single, married, a widow, or separated from her husband, is often a necessary factor in deciding important questions. Leading symptoms in the case. An important point is to enquire what brought her to seek advice. In the majority of cases it will be found that actual pain in some part or other is the leading symptom. In other cases pain may be entirely absent, or only i^resent under certain conditions. Others may sj^eak of a swelling in the abdomen as the leading feature. It sometimes happens that the patient complains only of some trivial deviation from health, yet, if her case be gone into systematically and carefully, important information will be forthcoming, which will enable us to suspect the nature of the trouble. Menstrual history. At the outset, in order to arrive at a correct opinion as to the contlition of the menstrual EXAMINATION IN (lENliUAL. 71 function, it iH lUHH'HHnry to nHcortaiii tlu^ normal cluirm't(ir of iiuMiHtruatioii in the individual, for thrro am ainon^^ woini'U wid(^ individual diH'cnMU'CK consiKtcnt with health. The [)oints to which attention should be directed are: 1. The (Kjc of rommrurcmcnL Men»trnation usually coinnitUKU's botwct^n tho ages of thirteen and fourteen years, but it is often seiMi earlier than that time and occasionally does not appear until later. Climate, race, and accidental causes often bring about a n nrked differ- ence in the time. 2. RIiijIIdii of flic Jloir. It sometimes liapptMis that aft(^r tlu^ first period or two, the patitint sees nothing again for some months, perhaps for a year or more, and after that time, recommences and continues regularly. With most women the flow comes on every twenty-eight days, but in some it appears at shorter intervals, and iji some at long(>r intervals than normal, while in others the menses do not appear with any regularity. On careful enquiry it will be found that the peculiarities are natiiral to the individuals and that the irrcigularity must be looked upon as regular for them. 3. Diirdfion of the floir. In the majority of women the period lasts four or five days, but here again consid(>rable variation is found, within physiological limits. In some it lasts only a day or two; in others the flow continues seven or eight days, without the presence of any abnormal condition. 4. The (hiilij omount. In this also there is consider- able room for variation, some soiling but few napkins throughout the whole period, while- others have to change very frequently. Enquiry as to how often the napkins have to be changed and the degree of soiling at each change, will give a fair estimate of the amount lost. 5. The (iffoidaiit si/nipfonis. In some patients there is no pain and no discomfort, but as a general thing, as the flow approaches, there is a sense of fulness, congestion, 72 MEDICAL ANb SURdlCAL GYNiiCOLOGY. disturbance and weight in the pc^lvic organs; often there is pain in a greater or Ivaa (logree. Sometimes it is a'^'companied by general disturbance, iiharacterized by frontal, occipital, or general headache, and by nausc^a and vomiting. The time at which the jmin begins varies in different individuals. In some the pain will begin a day or two before the flow, in others a few hours before, while in others it comes on with the flow. 0. Lcuvorrluvd. In a healthy woman there is no dis- charge, but some women have almost naturally a little discharge of a whitish character for a day or two after the flow cef "' s. Discharge c £ a thick glairy mucous in large quantities is however pathological. 7. Abnormal iHuu'aiions. The menses, previously normal, may have become too frequent or quite irregular; the duration or daily loss may have increased or dim- inished; or pain, previously absent, may have become a promiiAont symptom. In any case we should ascertain, how far the condition deviates from he: previous normal condition; what the change has been and .he time at which it set in. At the menopause the menses are often irregular; occasionally they stop for a month or two and even longer, then a re;^ulai period or two follows, after which they cease altogether. Sometimes they suddenly cease and the patient sees nothing more; in others again, the menopause is ushered in by considerable floodings. It must always b< borne in mind, especially in the case of flooding, that women are particularly liable to malignant disease at that time. Both for future reference and as a guide to the advisability of examinntion uy ineans of the sound, enquiry should be made, as to the date of the onsot of the last period and the time at which the last period closed. The obstetric history. Tt is most important to have the obstetric history of the patient, the history of her labo.s and miser, riages, if any, because a very consider- EXAMINATION IN GENERAL. 73 ablo ninount of illness which presents itself, is tlie result of impregnation nnd of disease following upon delivery or a., rtion. Ascertain the number of the chihlren, the character of each hi})or, tli<^ date of last delivery, whether there have been any premature labors or miscarriages, and, if so, whether any particular cause can be assigned for the occurrence. Illness during pregnancy and after delivery. Ascer- tain whether the health continued good during pregnancy. Unusual symptoms at that period are to be carefully enquired into. Illness after delivery is usunlly of a febrile character and the cause in nearly every case is attributable to septic mischief. Previous illnesses. Ascertain from the patient the nature of previous illnesses and whether associated with the ptdvic organs or not. Many of the troubles comi)lained of will be found to date from illness occurring at or soon after delivery or miscarriage. The history of the present illness. Ascertain, first of all, the date at which the present illness began, also the cause assigned for her illness. Of the particular symptoms to which attention should be drawn, pain stands first, because it is one of the most common. The site of the pain must be noted, whether it be continuous or spasmodic, and its chav<(cf('v, whether it be sharp and cutting or dull and aching, and also whether it be associated witli icnderuess. Pain or tenderness is a symptom of a very considerable number of diseases to which women are especially liable, such as pelvic peritonitis, parametritis, disease of the cellular tissue of the pelvis, luematocele, hicmatoma, inflammatory diseases of the appendages, metric.. s, adhesiotis left from previous inflammations, and finally tumors in the uterus, tubes o" ovaries. Dyspa;eunia may occur from various causes and is fre(iuently associated with vaginismus. It may be prim- ary, tlii '; is, it may have existed from the beginning of 74 MEDICAL AND SURGICAL OYN.ECOLOGY. attt'mpt.s at iioitus, or it :nay liavo ronxe on nftorwards. Tt may arise from i-oM^iMiita! di'tVcts, HssurcH about tlu' vulva, inflamed eonditioiis of the vau^iua, s])eei(ic or otherwiKc, iiiid it may be found in association with urethral earunele, or even with rectal tissurt' or piles. Tlio pnin is sometimes periotlieni, that is, associated with tlu> monthly periods, and, when so apiumring. becomes (me of the most prominent symi)toms of dysmi'n<)rrh(i>a. Ascertain where tlu^ pain is situated, whi'ther it extends into the liips. down tlu> thi,tz:lis, or for a c()nsideral)le distance over the abdomen; al"o when tlu' i)ain bej^ins, whetlier bi^fore the tlow or with the flow, and if before the tlow, the length of time before. Menorrhagia and metrorrhagia are often symptotns of severe trouble, and any deviation from the normal How, j)articularly if exttMisive. is to be carefully encpiinHl into. It may arise sim[)ly as the residt of sonu^ constitutional disturbance, as aiiivmia. clilorosis, purpura, but is often a prominent symi)tom in pelvic hiematcHude and lut^matoma, extra-uterine pregnancy, fungous endometritis, mucous polypi of the cervix, fibroids or myoma of the uterus projecting into tlu uterine cavity, subinvolution after continenient. and maligiuxnt disi-ase of the uterus. Amenorrhoea. During pregiuincy, as well as during lactation, amenorrluim is the ride, but the menses some- times persist (hiring the early months of pregnaiu^y and even later. Many women will c \tinue to have their periods regularly during nursing, comi .icing sometimes a month after delivery, and it is finite poss'bte UiV a woman to become pregnant during lactaiion. even if the menses have not appeared. It is necessary to renember these facts, because patients are apt to be misled in conseciuence, and. even when far advanced in pregnancy, are not aware of their condition. Local swelling or tumors. We should ascertain h'oin the patient if any swelling, either in the abdomen or in the genitals, has be"n noticed, where the swelling first EXAMINATION IN GENERAL. 75 jippciirc'd, if [HTKistcnt or vnriablo in its olmnvcitor, tlie site where it was first noticed and the direction in whicli it 1ms ^rown. Urinary symptoms. Note the elinrneter of the pain, if prt^sent, and tiie tinn^ at whic^li it (K!curs, whether dnrin^, previous to, or foUowing inieturition. Note also the frequency of micturition and whether it takes place more often at nij^ht than during the day. Inquire if there be difficulty in gc^tting tlu> water to pass, or whether tlie water constantly runs away or is i)assed involuntarily on coughing or straining. The clmrat^tt^r of the urine may be partly learned from the patient, but should always be tested by a proper urinalysis. Intestinal symptoms. Ascertain the frequency with whicn the bowels are relieved and if defecation be painful, difficult or associated with tenesmus. Note the condition of the tongue and incpiire as to the digestion, and whether nausea and vomiting be present; and. finally, ascertain what i>r<'ri<)iis trcdhticid, if any, has been adopted, how long it has been carried out, and with what results. PHYSICAL EXAMINATION. In the majority of cases correct inferences cannot Ije deduced fnnn verbal statements alone, and a physical examination becomes essential. The chief exception to this rule is in the case of young girls. It is most often for irregularities of menstruation and for leucorrham that young unmarried women seek relief, and as these dis- orders, in their casi\ are frecpiently depiMident upon the general health, hygienic measures and drugs will often accomplish all that is necessary. In fact only when such measures have been faithfully tried and proved ineffective, or when there is clear evidence of pelvic disease, is an examiiuition justifiable. Most examinations may be satis- factorily made with the patitmt. if at her home, lying in her bed or on a lounge, or it' the examination is to be 76 MEDICAL AND SURGICAL GYNAECOLOGY. C50iulnct(Kl in tho office, upon a conveniently arranged couch or chair. Position. The two cliief positiouH are the dorsal and Situs'. Of U>ss importance are the (jciiu-jtci'toi'dl, the ci'crf, and TrcniU'li'iibcrifs. In the dorsal position the patient lies upon the back; the head slightly raised; the knees drawn up and widely sei)arately; and, if necessary, the heels fixed in some kind of holes or stirrups. It is the best position for digital and bimanual examination, and is often employed for ordinary treatment, on account of its convenience. In Sims'' position the patient is i)laced on tho left side; the left side of the face rests on a cushion; the left breast touches the table, and the left arm is placed behind the body. Both knees are drawn up, the right being a little nearer the head and in front of the left. This position allows the introduction of one or two fingers high up behind the uterus, permits the use of Sims' speculum, and does not require such a degree of exposure as the dorsal. In the Trcndclcnhcry position, the knees are raised high above the head so that the body slants upward from the shoulders. It is rarely used for diagn(^stic purposes, its chief advantage lying in the additional facilities it offers the surgeon in operations upon the pelvic organs. In the (jenu-pectoral position the patient rests upon her knees, the upper part of the chest, the right side of the face and the right forearm. It is sometimes used to replace a retroverted uterus or prolapsed ovary. The erect position is used to discover a prolapsed uterus, a cystocele or rectocele. Examination under anaesthetics. Nearlj' all exam- inations can be made with a full knowledge on the part of the patient, and it should be a rule to examine first in *,hat manner, but it is sometimes impossible, under such 'r- cumstances, to obtain satisfactory results. Occasionally EXAMINATION IN GENERAL. 77 palpation is so painful that the patient cannot endure the slightest manipulation, and, even when no pain is present, it is often found that as soon as the hand touches the abdomen, the muscles, more especially the recti, at once become so tense that it is impossible to feel anything that may be beneath them. Under such circumstances the use of an anjusthetic is not only justifiable, but absolutely necessary, to make a correct diagnosis. Methods of examination. Three methods, under ordinary circumstances, are made use of: The visual, the Dumudl or (lujital, and the instruiiicntal. VisiKil hispcctioii of the external genitals will often reveal many facts, such as atresia of tlici hymen, swelling of the vulvo-vaginal glands, the presence of papillary growths, venereal ulcers, discharges, urethral caruncle, a lacerated perineum, or prolapse of the vaginal walls. Difjitdl ('.rainiii((tion per vfufiHdin. The fingers, especially the index fingers, are instruments of the greatest value in acquiring iid'ormntion, the sense of touch replacing that of vision. The partly closed hand, with the index finger extended, is passed along the inner side of the thigh and, on reaching the vulva, abnormalities of the labia may be detected. The index finger is gently pushed between them into the vagina, examining at the sanu^ time for any peculiarity of the hyuKni, obstructions, pr()la^)sed organs, or gaping from relaxation or laceration. The vaginal walls are palpated to detect abnormalities in them, or of the rectum, or of the urethra or bladder. The finger end next reaches the cervix and is swept around to examine the fornices. By palpation, tlu^ size, shape, and consistency of the cervix and the shape of the external os are made out. The fingers i)ushed up h'lhind will (h^tect a retroverted uterus or displaced ovary, and, when pushed up in front, will feel an anteflexed uterus or ti'e trigone of tiie bladder. 78 MEDICAL AND SUROICAL GYNECOLOGY. Dtjfital cxfimivaiioii x>er rectum is best porformod in Sims' position. Besides ovideiico of disease of the rectum obtained by this method, it is n useful method to empk)y in the case of virgins with sensitive liymen or small vagina. Sometimes the uterus and appendag(>s are better felt from the rectum than from the vagina, and, in case of abdominal tumors, valuable information is to be obtained tluuH^by. Abnormal conditions of the coccyx, such as ankylosis or fracture, can be detected at the same time. Bi'iikoukU examiiuition. In order to secure the re- quired information it is often necessary to make use of both hands. With one index finger impinging on the os, after the method already describcnl, the other hand is placed above the pubes and the finger tips pressed down with increasing firmness until the fundus is felt and the organ made to lie between the examining fingers of the two hands. If the body of the uterus is not found, it should be sought for either in front of or beliind the cervix. By this method, the outline, size and shape of the uterus can be made out. By pressing well down beside the uterus, the tubes and ovaries may be palpated, and the method is of the utmost advantage in the diagnosis of pelvic tumors. Instrumental examination. The vaginal spcoiJiini is an instrument, by the aid of wliich we are enabled to look into the vagina and to treat various pathological conditions found. Of these there are a great variety, but the number may be reduced to three types, the cylindrical, the pluri- valve, and the single blade. The cylindrical speculum, as repri^sented by P^erguson's, once so popular, is now seldom used, as the exposure is too limited and the space within it too cramped. The hiiHihu' speculum consists of two blades, joined at one end, and looks anil opens something like the bill of a duck, The lower blade is usually a little longer than the upper one. It is introduced closed, either in the dorsal iiiji^ EXAMINATION IN GENERAL. 79 Fic. i8.— Highee's Bivalve Speculum. or Sims' position, niid is then expftndod by a screw or lever. As the bla(U^s are expandcnl, the cervix settles down on th(^ lower or posterior blade and thus comeB into view. There are several varieties, of which Cusco's, Brewer's, and Higbee's form fair samples. It is a very satisfactory instriiment, botli for inspection and treatnuuit, and can be used witliout an assistant. The tri-valve (Nel- son's or Mott's) has two narrow blades, in place of the anterior blade of the bi-valve. Thi^ sin<j;le blade, or Sims' speculum or retractor, is practically a Hatti'ned blade, made somewhat concave on the vaginal surface, jind to which a slender liaiidle is attached. For convenience, two blades of different sizes, one at each end, an^ attached to the handle. When inserted it shows the uterus and the anterior wall of the vagina in their normal position and relations, its object biung to pull back the p(>rin(ml body and the posterior vaginal wall. Besides this ad- vantage, it readily per- mits of treatment, and is the sijeculum chiefly used for opc^rations upon the uterus and vagina. If the cervix does not readily come into view, the failure Fig. ro.— Sims' Speculum. • . j. -i. i • i ^ IS owing to its being ob- scured by the anterior vaginal wall. To overcome this difficulty, a flat blade, shaped like a spatula, or fenestrated, and called a dcprcsso)', is made use of. To overcom(> the necessity for having an assistant when using Sims' speculum, many ingenious modiflcations nave been do- 80 MEDICAL AND SURGICAL GYNECOLOGY. vised to make it self-retnining, but in every case their application is troublesome and often unsatisfactory. The uterine sound is an instrument made of a more or less flexible metal, usually copper, with a slightly bulbous extremity, and at a distance of two and one-lialf inches from the extremity, is another bulb, indicating the length of the normal uterus. It should first be bent to correspond with the supposed curve of the canal, as found by bimanual examination. When introduced, it indicates the longtli and direction of the uterine cavity, and its relation to any mass pn^ssing into or occupying that space. The mobility of the body of the uterus may be determined also, as well as the relation which it bears to a tumor or other ma.ss -ill- c\JtKTZo Fig 2o. — Simpson's Sound. adjacent to it. In is a very useful and, when properly used, harmless instrument, but in handling it, it must never be forgotten that it is cajjable of perforating the uterine wall, and that it is being introduced into a cavity from which absorption easily takes place. In its intro- duction much difficulty is often experienced by the point catching in the folds of mucous membrane in the cervix, or by the opposition made by flexion. The difficulty may be overcome by embedding the curved point of a tenaculum in the tissues of the anterior lip and making counter- traction, the effect of which will be to straighten out the canal. The pvohe is a much thinner and very flexible rod used exclusively for exploring the inside of the uterine cavity. Uterine dressinp forrepF., of which a great variety have been devised, are invaluable for wiping out the EXAMINATION IN GENERAL. 81 cervical mucous while mnkinpf inspection, for disinfecting the vnginnl foniices, and for carrying medicated material to the intended point of application. Bozem.in's Pressing Forceps. The vuhcllurn is a pair of forceps, each blade of which ends in a double hook. It is used for seizing and pulling Fig 22. — Viilsellum Forceps. tissue, and is thus useful in steadying the uterus, while introducing the sound or dilating the cervical canal. Examination of the interior of the uterus. When bimanual and speculum examinations make it evident that the disease is seated within the uterus, an exi)loration of its interior is essential. Usually the cervical canal presents an effectual barrier to exploratioTi, eithe. by fin,»er or instrument, and some method of dilatation must therefore be used. This may be done slowlij by means of tents, or rdpidly by graduated dilators or dilatating forceps. Gradual dilatation, by means of tents, has now fallen into complete disuse, except in isolated cases. From the fact that it is impossible to render them aseptic and from the necessity for the use of two or three to obtain sufficient dilatation, their use exposes the patient to great danger. For diagnostic puri)oses and as part of treatment, dilatation 82 MEDICAL AND SURGICAL GYNECOLOGY. ia bost nofioniplisluHl mpidly by instruiiKMits. For tlio lower (lejijrcc'H of (lilatnti(jn. Hunks' luinl riibb(^r or Hti^el Krci. 23. — Hanks' ililators. dilators, which como in .1 set of six, embracing twolvo numbers, are very serviceable. Commencing witli the largest that will enter the canal, they are passed in, one after another, until the r(H|uired degiH^e of dilatation has bt^en re( quired. For a higher degree of dilatation, som(^ of tlu> steel branched dilators may be used. A very satisfactory instrument, perhaps the best, is Goodell's modification of Ellinger's, but being rather thick in the blades, it niay be: found imposs- ible to insert them when the cervical canal is small, lender such circum- stances it is best to commence with a pair of lighter blades, such as that known as Wylic^'s. After insertion, the handles are to be gradually compressed and, as the parts yield to firm, slow pressure, what is gained may be held by the screw or ratchet. The use of this instrument, as well as of the graduated dilators, will be facilitated if the cervix be steadied with a vulsellum. Fi<;. 24. Gooilell's Di'ntor. EXAMINATION IN GENERAL. 8;{ Th<' cuvi'ttc is nil instrument used for scraping ott' or romoving pntliologicnl or otlu^r structureH from the inside of the uterus. Althougli mostly used as a theraixnitic agent, 8om(>times it is used to secure a specimen for gross or microscopical examination. Tlic^re are two varieties in use, one sharp and stitt', the other dull and somewhat flexible. From the frequent association of urirary symi)toms with uterine diseas(>s, the best nu'thods for examining the urethra and bladder should b(^ known to all [)ractitioners. Some knowlcnlge of the condition of tlu' lower part of the urethra may bt^ gained by inspection, some bladder and urethral affections may be recognised by examination with the linger, but for the deti^rmination of the exact condition of the lining nnunbrane of th(> urethra, an endoscope is Fii;s. 25, 26, 27. — Skene's Endoscope. necessary. By inserting to its full length a simple tube, sirailar to an ear speculum, the field being illuminated with a head mirror, the whole urethra may be fairly well inspected as the tube is being withdrawn. The most satisfactory urethral endoscope is that known as Skene's. By means of it, not only the neck of the bladder and urethra may be inspected, but applications by means of cotton or a spray may be made to any part of the canal. The bladder can be explored digitally by first gradually IMAGE EVALUATION TEST TARGET (MT-3) A {/ ^^i^.. b> i^^,^ €^r '/ 4 mC/s 1.0 I.I 1.25 |50 '"^ vs. ..„ IM 2.2 2.0 U ill 1.6 Photographic Sciences Corporation 23 WEST MAIN STREET WEBSTER, N.Y 14580 (716) 8/2-45r3 ^ iV "% m \\x ^1> 6"^ >^ '« «> -«*• 84 MEDICAL AND SURGICAL GYNJIOOLOGY. dilating tlie urethrn with Simon'R instruments until the largest has been passed, after which the finger can usually be inserted into the bladder. Dr. Howard A. Kelly has extended and simplified the technique of the examination of the bladder and ureters, which permits of direct visual inspection of the female Kio. 28.--noul>le Uretlir.-il Dilator. bladd(^r and ureteral orifices, and which renders it possible to complete the catheterization of both ureters within a few minutes after the introduction of the specidum. The following instruments are required: A urethral dilator; a series of specula with obturators; a head mirror with some form of artificial light; a im'ir of delicate mouse-toothed forceps; an evacuator for withdrawing residual urine; a Figs. 29, 30. — Speculum .nnrl Obturator {% natural size). ureteral searcher, and a ureteral catheter. The hips are somewhat elevated, and, after the necessary degree of dilatation, a proper sized speculum is introduced and the obturator withdrawn. By means of reflected light from the head mirror, it is possible to examine fully the interior EXAMINATION IN GENERAL. 85 of tho bladder. Rosidunl urino obstructiiif? tlu' view may be removed witli the evacuator, or, if very small in amount, by little balls of absorbent (cotton held in tlu' mouse-toothed foreeps. After a litth> prac^tiee the sites of the urethral oritiees can be located. Dr. Kelly su^^m'sts the following valuable aid for locatinjj: them: "A point is marked on 'he cystoscopi^ at a distantn^ of five and one- half centimetres from the vesical end, and from the jMnnt Fig. 31. — Cystoscopic examination of bladder and direct catheterization ot ureters. two diverging lines are draw toward the handle, with an angle of sixty degrees between them. The speculum is introduced up to the point of the V and turned to the right or left, until one side of the V is in a line with the axis of the body. By elevating the endoscope until it touches the floor of the bladder, the ureteral orifices will nearly always be within the area covered by the orifice of the speculum." 86 MEDICAL ANU SUIUJICAL OYN. ECOLOGY. Tho RonroluT in itoxt omploytMl, nnd if what, is scmmi is ronlly the oritici', it will at oiico pass ri'adily into it. Tho ureteral catheter may then be subHtituted for the searcher and the iirine coUected, as it passes from t\w kidney. Examination of the abdomen. In a certain number of cases inspection of the abdomen is important. The practiced eyo can distinj^uish the pointed prominence caused by a tumor or pregnancy, and the Hat enhxr^e- ment. owin>^ to the presence of ascites or supi'r-abun(hint adipose tissue; and vdien present, pigmentation, strije albicantes, and a protruded navel are readily observed. By paljAtion, the practised touch will show tho size, con- sistency, and relations of a tumor, its mobility, and its smoothness or irregularities. FcrcHSsioii permits of defining, with greater accuracy, the height to which a tumor rises, and the extent and mobility of the area of dullness. Auscultdiiou is of value onl^ in the differential diagnosis of pregnancy from other varieties of abdominal tumor. CHAPTER VIII. GYNECOLOGICAL THERAPEUTICS. To be successful in the treatnxent of diseases of women, pelvic disorders are not to be looked upon as isolated conditions, but must be viewed, in a large number of cases, as arising out of an existing or pre-existing con- stitutional state, or faulty regime of the patient. Thus the circulation and the digestive and other imijortant systems may influence or be influenced, by the pelvic organs, and when deciding upon a line of treatment, the general condition of the patient must never be lost sight of. GYNAECOLOGICAL THERAPEUTICS. 87 Cicucvdl hi/jjicnc is nn importntit fnctor. Tlio mind Hhould be ns far as possible froo from anxiety hikI strain, yet at the same time actively (employed in some healthy, intelle(^tual pursuit, and the body stimulated by exercise suited to taste and circumstances. The strictest attention should bo paid to the menstrual period, and every girl should be taught how to take care of herself during the performance of that important function. Regularity in the action of the bowels and attention to their daily evacuation, regular attention to the calls for micturition, attention to the functions of the skin, and regularity of meals and sleep, both as regards time and duration, are also of great importance. The clothing, while not being too heavy, should be of such texture and material, and so distributed, as to keep every part of the body equally warm. Exercise in some form or other is often bene- ficial, but should never be excessive. What the particular form of exercise shall be, must dejjend upon the taste or occupation of the individual. Each condition with which we have to deal will suggest points ai)plicable to it. In the i)elvis, as elsewhere, pain and disordered functions are indications for rest, and in no department of medicine is rest more essential than in this. In the majority of patients, their sufferings are due to fulness of the vessels within the pelvis, and to overcome this r>»st in the recumbent position is absolutely necessary. But rest to be complete must be not only local and general, but physiological as well. A very large number of gymecological jjatients suffer from aniBmia, and often from anorexia. Careful attention must be given to the diet, and when so prescribing, precise orders should be given in regard to the time, the quality and quantity of meals, as well as to a proper variety. Drugs. Pi(r<j(ifir<'s In no class of diseases are purgatives more useful. Constipation, acting locally, maj 88 MEUKJAL AND SURGICAL GYNAECOLOGY. soriously displnce tlie pelvic, viscera, or by pressure pro- mote congv^stioii nnd discomfort. In many cases of chronic pelvic disefxse, a course of jjurgatives, such as sulphate of magnesia, cascara sagrada, aloes, with an occasional dose of calomel, will greatly relieve the patient, and where there if. systemic portal congestion, morning draughts cf Carlsbad salts, or Hunyadi Janos, Apenta, or Franz Josef mineral waters will, by their mild laxative action, afford much relief In acute pelvic inflammation, saline purgatives aie highly beneficial. Enemata of warm water, and rectal injections of glycerine, are useful adjuncts or alternatives. Tonics. Nearly all kinds may find a place in the treatment of pelvic disease. Unless contra-indicated, iron, in some form, is one of the most active, and when ad- ministered gives the best results when combined with a purgative. Arsenic is valuable when lucorrhcea is present in amemic girls with a chronic catarrh of the vagina or cervix. Combined with iron, it acts well in ansemia and chlorosis with scanty catamenia. Quinine, aside from its specific effect, has a special tonic action on the uterine muscles, and is therefore useful as an adjunct. Seddtires, especially the stronger ones, should be administered with great caution, for often the condition for which they are j^rescribed is a recurrent one, and the repeated administration may lead to the abuse of these agents. Special Gynaecological Drugs. Ergot is used for two main purposes, to encourage uterine contraction and to lessen uterine hemorrhage. On this account, it is ad- ministered for passive uterine hemorrhage, in uterine fibroids, fungous endometritis, subinvolution, and in uterine congestion. In chronic hemorrhage, or when it is given for lengthened periods, it should be combined with acids and purgatives. GYN.ECOLOGKiAL THERAPEUTICS. 81) (losi^/ipiiim, in the form of fluid extract, or decoction freshly prepared, is an ommenap-o^ue and partvirient. It has a tonic influence on the uteruB, relieves pain, and often seems to act better than ergot in arresting imssive hemorrhage. Hi/drastis Camidrnsts, in the form of fluid extract or tincture, has a decided ecbolic action and, if taken regu- larly, will check chronic hemorrhage, and besides has a decidedly sedative effect. HiinKimclis has been accorded a high place i:i the scale of uterine haemostatics wliere passive engorgement exists. CcDinabis ImJica, in the form of extract, is extremely useful in cases of menorraghia with pain, in dysmenorrhoja, and in some cases of fibroids. It is apt to affect som<* women i)eculiarly, and at first must be given cautiously and in small doses. Viburnum pr'nnifo] in m is an anti-spasmodic, relieving painful contraction of both voluntary and involuntary muscles and is, therefore, useful to prevent abortion in catses where uterine contraction precedes the death of the foetus. A large group of anti-spasmodics and sedatives may be used for the relief of pelvic pain, among which may be mentioned some of the coal tar derivatives, such as phcnfivcfine. The Bromiih'fi allay th.i pain and restlessness due to increased local tension, as in congestion of the ovary. They tend to lessen hemorrhage of a passive type, and are excellent remedies to anticipate the headache and nausea which precede dysmenorrluwa. Chloride of Ammoninm acts upon the portal system and thus tends to relieve pelvic congestion. It is useful in simple congestion, subinvolution aiul chronic metritis. Chloride of Colrinni, given thrice daily, in doses of ten to twenty grains, often acts like a charm in some cases of menorrhagia. <.K) MEDICAL ANO SURdlCAL (iYN.ECOLOCJY. Jicsol rents nro oftou cnlli'd for in chronic inHuniniation, to prom(>tc absorption of lon^ stmuling iiitiaininntory exudation. The most important of those arc, iodine in the form of iodide of potassium, sodium or ammonium; mercury iu tlu^ form of bichUiride, and gold in the form of chh)ri(U« of sodium and gold. The local therapeutic effects to be derived from the application of Itnif and cold are well known. 1. E.riernal aj>pli('<itioii. Cold, locally applied, is a depressant, checking the vital action and diminisliing the bh)od supply, and hence is useful in hypenvMnia or con- gestion of the pelvic organs. It may be applitnl in the form of ice-bags, or by means of a Leiter coil. Hc<d, in the form of hot baths, is mainly sedative, relaxing the skin and its glands, dilating the i)eripheral vessels, and thus relieving congestions of internal viscera. It is therefore useful in congestive dysmenorrhoia, and, by its power of relieving muscular spasm, is serviceable in spasmodic dysm(>norrho>a and in cases of uterine, tubal and other pelvic and abdominal colics. Hot foot and sitz h(itlt)'- act somewhat similarly and are particularly useful in relieving pelvic congestion produced by sudden arrest of the cntamenia. Mustord, added to such baths, increases their effects. Pout f ices and fonundfitioiis. both as to their utility and actio'i, may be considered as local baths. If a sedative effect is required, opium, in the form of laudanum, may be added; if a stimulating effect is required, turpen- tine. Heat may also be aj^plied, locally, by means of hot Wider cans and rubber bags. 2. Iideritfd ((pjdiecdion. Hot water has a far more extensive field of usefulness in the pathology of women's diseases than any one agent. Hot water may be made to enter the vagina while in a bath, by means of a speculum, but the usual method employed is by means of a dourlie (ippandns. In all cases, the flow into the vagina should be continuous, hence, for the purpose, an elevated ci-uJie- OYN.Et'OLOCilCAL THliUAl'EUTICS. 91 (•nil. or sonip syplion nrran^tMinMit, is bi'ttcr tlum the ordiiuiry luviul-bulb syriti^o. The vfiKin'il nozzlo should bo of somo smooth mntorial, easily innde nscptic, and, during administration, tin* patient should lie flat on the back witli the pelvis raised on a Ixul-lxitli. For merely cleansing tlK> vagina, tepid water will suffice, but its eliVit may be increased by adding a drnm of bicarbonate of soda, borax, or boracic acid, to the pint. For the relief of congestion, water, at a temperature of 100° to 105° F. is indicated, but for the arrest of hemorrhage, a higher temperature is required. By the addition of medicinal agents the douche can be rendered antiseptic, anodyne, astringent, or sedative. Cold water applied to the vagina is unsafe and should not be made use of. Counter irritation to the skin may be applied in a variety of waj'^s by such drugs as mu.stard, turpentine, iodine, croton oil, or cantharides. Applications to the vagina may be made in varibus ways. Donrlicsi are a convenient way of applying medi- caments. If for antiseptic purposes, bichlori.le of nuTcury, 1 to 4000 to 1 to 2000, and carbolic acid 1 to 200, may be used, but their prolonged or frequent use is to bo avoided, owing to the dangers from absorption. Weak solutions of potassium permanganate and of sulplio- carbolate of zinc may also be used, but r.re not so effectual. If required for astringent purposes, plumbi acetate, zinc sulphate, alum, and tannin are the best. Mcdicdtcd ix'SSfirics may be used for tlieir local effect, as well as for their remote, and when for the latter, double the usual dose should be administered. Pessaries of glycerine, combined witli gelatine, will relieve vaginal congestion and encourage se(;retion. If so desired, drugs may be added to such pessaries, and it is in this form that ichthyol has its most useful sedative and absorbent api)lication. particularly in subinvolution asso- ciated with endocervicitis and granular erosion. The \)2 MEDICAL AND SURC.ICAL OYN.ECOLOOY. dnij;H nu)st oftcMi usimI nn scdativcH nro ctx^nino. niori)1jin, extract of lu'lladoiin!! and extract of henbane; as astrin- j^entH. alum and tannin, and. when so ein[)loyed, may be combined with cocno-butter or gelatim^ For this purpose, gauze, too, saturated with various int^redients, is readily ap[)lie(l. Tdinpons macU' from wool or absorbent cotton, roHed and tied in sizes most convenient for the work recpiired of them, may be used to advantage as conveyers of medicinal agents, such as boric acid, ichthyol in glycerine, lysol, aristol, balsam of Peru, aciueous solutions of alum, and other agents; and, when so m(>(licated, serve a good purpose for stimulating, sedative, or astringent apjjlica- tions. They are also used as temporary means of Hujjnnrt. for exerting pressure, and to soften and stretch organized bands within the pelvis. Tampons may be also employed to plug or to tightly pack the vagina for the arrest of hemorrhage and to maintain an aseptic condition. Direct application of drugs may be made, through a speculum, to any affected area of tlu^ vagina by means of a pledget of absorbent cotton held in the jaws of a pair of uterine dressing forceps. Nitrate of silver, in various strengths, solutions of sulphate of copj^er, tincture of iodine, carbolic acid, iodized pheno?. litiuor ferri perch- loride, ichthoyl, glycerite of tannin and such like, are all useful therapeutics agents in appropriate cases. Applications to the uterus. The same drugs used for the vagina may also be used for the vaginal portion of the uterus, and are to be applied in the same way. To npi)ly substances to the cervical canal, it must be exposed, and by the aid of a Burrage's sijeculum and cotton holder, the mendicament is directly applied. Until very recently, it was the practice to make applications of many of the remedies mentioned to the cavity of the uterus, but it has now fallen into disuse, and in cases, where previously employed, the practice of to-day is thorough curettage and GYNAECOLOGICAL THEKAPEUTICS. 93 cleniisiiig nnd drainiuj^ of tho canal. Wlioii that has boon thoroughly douo, it is all that is nocosKary. Intra-uterine injections nrc nuioh inoro ilangorous than va^'iual. Largo utorino injootions of w> rni wator, medioatod or othorwiHo, nmy bo usod for olon using nnd disinfocting tho utorus, and for chocking lioniorrliago. If tho corvix has boon thoroughly dilatod, a curved glass CX: Fig. .!2. — Burrage's Cervical .Speculum, a, tulie ; fi, handle ; r, movable cl.isp ; ri •.mall tulie at right angles to main lulie ; ,•, smaller cervical tube to replace a ; ./, ihmrator fitting the two tubes. single current tube is proforable, but if tho cervical canal is not so \s,'id'), a metal double-current utorino tube sliould be used, such as Bosoman's, a Cusco's or other spocudum having boon previously introduced, and while administer- ing tho flow should bo carefully watxihed. Vui. 33. — Intra-uterinc Douche. Vesical injections are much used in the treatment of diseases of the bladder. For large injc^ctions, a fountain syringe with a hard or soft catlu^ter attached and a two- way stop-cock whi(^h allows tho bladder to bo alternately tilled and emptied, acts very well. Wluu\ simple irrigation is required, Nott's doubh^ current catheter proves very serviceable. A simple, yot very effectual vesical douche may be made by attaching to one end of a rubber tube a 94 MEDICAL AND SUUOICAL OYN^COLOUY. fr small funnel, or tho barrel of n lar^o ^lasH male syringe, and to the other an ordinary glass oatlu^ter. Tlu^ tluid is pour(uI into tlu^ reeeptaele, lu^ld at tlu^ nupiired distance above the patient, and, when suftieitMit has I'ntered, the rec(>ptaole is lowered, which permits the fluid to be syphoned out. Curetting. In the treatmiMit of diseases of the uterus this minor opera- tion is often demanded. It retiuires the administration of an anaesthetic, jdthough some can undergo the ordeal without it. The cervical canal is first dilattnl carefully with steel dilators to such a size as will readily admit the curette. The cavity of the uterus is next fl\ished through a Burrnge's spec- ulum, or by means of an intra-uterine r^ douche, with a 1 to 2000 solution of bichloride. Fig. 34.- Tenacula The cervix being grasped with a vulsellum or ten- aculum, to steady the uterus, the sharp curette is introduced and the entire cavity carefully scrap-id, the persisten 5e and vigor with which this is done being governed by the conditions Ijre-sent. The antierior and pos- terior walls, the lateral sulci where these two come together, the fundus, and tlu^ recesses of the cornua are scraped in turn. The cavity is next irrigated with the warm bichloride solution, and dried with a little cotton on a holdi>r. Should circumstance ? demand it, the cavity may be touched over with carbolic acid, tincture of iodine, or iodized jjlienol, after which it Fk;. 35. — Wire- loop Curettes. Fig. 36. — Sharp Curette. (lYN.ECOUKJIC'AL THEKAl'lirTIOS. 9B Ih aj^ftiii to b(^ (Irit'd witli cotton. Tf (icemod adviHnblc, tlio uterus nuiy be draint'd by the introduction of a Ktrip of iodoform ^auzci, or it may be packed with the Hanm material. Aa a rule, ^ood draiuag(> is all that is uocesHary after thorough curettage. Pelvic massage. Though massage, in its dit1"'erent forms, enters into tlu^ treatmcMit of various femaU^ afVec- tions, it is also valuable as a part of the giuieral care of the body, both to increase the activity of the blood (uimuit HO as to bring it mori^ fn^quently in contact with the oxygen of the lungs, and to promote nutrition, by making the muscles work out what elements they have alreatly taken up, but have not utilized. By this means, the body at largi> becomes more vigorous and robust, and thus will respond more effectually to therapeutics and to the local treiatment of the organs, the care of which are being considered. A form of massage, known as pelvic massage, has been elaborati'd and brought to bear upon the class of ailments which usually prove most intractable, and for the treatment of which the means at our commantl have always been too few. This class of treatment has given excellent results, when judiciously undertaken, in selected cases, and when carried out with patience and with a clear perception of its indications. It is applicable to a great diversity of ailments, but it may be stated, in a general way, that chronic; female affections, such as persistent pain, constantly recurring congestion, displacements, de- formities and fixation of organs, attributable to lack of support or increased weight, peritoneal inflammations and lymph deposits, are the ones which we may hope to benefit most by this method. As opposi^d to this class, there are also conditions entirely unsuited to such handling. Mas- sage should never be attempted in any acute disease, nor in any acute exacerbation of a pre-existing disease, nor in the presence of pus tubes or pus in any part of the pelvis, nor in cases of pregnancy, normal, or still less, abnormal 96 MEDICAL AND SURGICAL GYNAECOLOGY. or ectopic. The only exception is a retroverted uterus before the third month. Tuberculosis of the peritoneum is another contraindication, also ovarian cystoma, cysts of the broad ligaments, fibroids and malignant growths any- where within tln^ pelvis. Massage, in the diseases specified, consists briefly in kneading the pelvic masses, applying friction to them to cause their absorption, and in moving the uterus in different directions to stretch and free its adhesions. The manipulation is carried out with one hand pressing through the abdominal wall and with one or two fingers of the second hand in the vagina. The vaginal fingers are used mostly for lifting up and fixing the uterus or pelvic masses, the manipulation being carried on, for the most part, by the abdominal hand. CHAPTER IX. POST-OPERATIVE TREATMENT. There are certain well-defined principles which may be followed in conducting the after-treatment of a patient upon whom an abdominal section has been performed, the observance of which is of the greatest importance, and the neglect of which may be attended with serious results. After operation the patient is to be remov'ed to lu>-r bed, previously made warm, and hot-water bottles carefully placed on each side. One-thirty-second of a grain of strychnine is at once given, and repeated every four hours for the first twenty-four hours; every six hours for the next twenty-four hours, and after that, only if required. It is (extremely difiieult to lay down definite rules regarding food and drink, as patients respond differently under the same management, and the greatest ingiuiuity is often required. During the first twelve hours it will be found POST-OPERATIVE TREATMENT. 07 preferable to give nothing except small quantities of toast water, or warm water, from one to two teaspoonsful every ten or fifteen minutes; or ten to fifteen drops of sherry m two or three teaspoonsful of soda water, testing the ability of the stomach to retain and absorb it. This frequency of administratioTi is not only tolerated, but is very com- forting to the patient, relieving the thirst and diminishing vomiting as well, when present. Ice, as a rule, while grateful to the mouth of the patient, is not as well borne as warm water, and the patient is never satisfied; besides, the injection into the stomach of cold wati^r is apt to cause nausea. The distressing thirst, so often complained of after operation, may be relieved by frequent injections, into the rectum, of half a pint of normal salt solution, and with some it is the practice to inject high up into the sigmoid flexure a quart of this solution, before the patient leaves the operating table. After the first twelve hours small quantities of chicken broth or beef tea, half an ounce every half hour, may be allowed, the time between administrations being extended as the amount given is increased. Albumen water, into which the juice of a ripe orange has been S(iueezed, is often well tolerated and very comforting. Milk, as n rule, is not a good substance to give by the mouth. It is not easily digested in the stomach, and the thick curds formed are either ejected, or act as an irritant in the intestinal canal. Peptonized milk has not this objection, and, as a rule, is well retained, but many patients object to the peculiar tast(^ Weak oyster-broth has often been retained with much satisfaction, when other nutriment has been rejected. Small (piantities of ginger ale sometimes act as a sedative to the stomach, relieve thirst and flatulence, and are often eagerly demand- ed by the patient. At the end of the third day the dietary may be increased and administered every two hours. Milk may now be given, combined with lime- water. Such articles of diet as gruel, light thin porridge, 98 MEI)I(!AL AND SURftlCAL OYN^OOLOGY. custards, rico, sago, tapioca, thin strips of bread and butter and poached eggs may be gradually added to the list until the eighth or ninth day, when some solids may be introduced. The arms, legs, and chest may be sponged with warm alcohol, or with soaj) and water, and subsequently con- valescence is promoted by frequent sponging and by rub- bing the body with alcohol. If there is much restlessness, or if the patient suffers severe pain, a small hypodermatic of morphia, one-sixth to one-quarter of a grain, may be administered, but the routine employment of it is to be condemned. It is much better to encourage the patients to control themselves and to endeavor to endure the pain. It delays healing, checks secretion and elimination, as well as the peristaltic action of the bowels, functions so much required at this critical time, besides it places the patient in such a . mood as to be an unsafe monitor of untoward or alarming symptoms. Purgatives. It is imperative to obtain a movement of the bowels at as early a period as possible, and it is astonishing to note the great change for the better which takes place when this has been satisfactorily accomplished. If, at the end of forty-eight hours, a good satisfactory movement of the bowels has been obtained, and the pulse below one hundred, the patient is convalescent. If, on the other hand, the bowels remain unmoved, in spite of efforts to open them, and tympany appears, with rising pulse, it is a serious matter. On the second day after operation, an effort may be made to move the bowels, some administering grain doses of calomel every hour until five doses have been given; others recommend teaspoonful doses oi Rochelle or Epsom salts every two hours until three doses have been given. Medicines by tlie mouth for this purp';.->e are, however, often contra-indicated, causing nausea or the upsetting of the stomach. The most satisfactory method consists in the administration, POST-OPEKATIVE TREATMENT. IH) on the second day, of nn enema of warm water and soap- suds, introduced as high up as possible, by means of a rectal tube or large catheter. If the enema is not effectual it may be repeatt d once or twice at intervals of two or three hours. Fl( tulcnce, or accumulation of flatus in the bowels, is often a distressing symptom, but generally may be effectually relieved by adding spirits of turpentine to the enema, aided by light massage over the region of the colon. A few drops of tincture of capsicum or of essence of peppermint, in water, will often giv(^ material relief. Tlu^ patient should be catheter i zed shortly after operation, and, if necessary, every six hours afterwards, but she is to be encouraged to attempt to void the urine voluntarily, provided it can be done without much straining. Nearly every patient is restless and suffers more or less pain, which may be relieved by some slight change in position, or by putting a soft pad under the head and shoulders, or under the bends of the knees. Shock following prolonged, or any operation, can best be treated by kc^eping up the dry heat to the body and by hypodermatics of whiskey or b-andy and strychnine. The routine practice of injections ot strychnine, commenced at once after operation, will often prevent the appearance of the symptoms of shock. Hemorrhage. Indications of collapse, with a falling temperature and rapidly rising pulsi^, points to this grave danger, and no time must be lost in re-opening the wound and se(Oving for the mischief, and stimulating treatment afterwards pursutnl by every effort known, (rreat benefit will be derived from rectal injections of normal salt solution, but more particularly from injections of the same solution into the pectoral region by means of a small aspirating lUHHlle attached to an ordinary enema syringe. Large quantities can thus be injected, if rigidly persisted in. The vomiting, due to the anaesthesia, should be over at the end of eighteen or twenty-four hours, but sometimes it 100 MEDICAL AND SURGICAL GYNAECOLOGY. persists longer niid becomt's n most troublesome symptom. When vomiting continues after the third day, especially wluni the fluid is expelled without much apparent force, peritonitis is to be feared, lender the circumstances nothing is to be given by the mouth whatever, but rectal enema of peptonized milk or beef tea and the white of egg may be given instead. To allay thirst and dryness of the mouth it may be frequently rinsed out with cold water. As a rule the patient should not be allowed to sit up in bed until the eighteenth day. At the end of the third week she may be allowed to get out of bed, and at the end of the fourth week, allowed to walk, but before doing so she should be furnished with an abdominal bandage, to prevent any opening of the incision, to be subsequently followed by a hernia. The after-treatment of plastic operations for the repair of the perineum or cervix resolves itself into rest and cleanliness. The patient should remain in bed for two weeks, and after that should take another week in getting up and about. If a gauze tampon has been introduced into the vagina, it slioul 1 bo removed after forty-eight hours, and a warm sterile \' iter douche given daily. Two aloin, strychnine an l)elladonna granules may bo administered on the second evening after operation, followed by a rectal enema in the morning. CHAPTER X. GYN/ECOLOGICAL APPLICATION OF ELECTRIC CURRENTS. But two currents may be said to be in use in gynre- cologieal therapeutics; the <i<ilr(Uii(' or direct current, and the Faradic, induced or iutcrrupted current. The articles considered necessary for the application of the galvanic current are, a battery, composed of from APPLICATION OF ELECTUIC CURRENTS. 101 forty-tivo to Bovonty Loolnnche coIIh. set up " in scTios," or tin- supply terminals of nn inenndesccnt electric li^lit current. A riirrcid controller, such us the Mnssey, or some reliable rhcosiot, to regulate or turn off or on the current; a (jdlvdnometcr, indicating from 1 to 500 milliam- lieres; rhcophorcs or flexible metallic cords, for conducti ng the current; various forms of eh'cirodvs for its application, and a romninfotor or pole chamicr. Instead of such a bulky battery, many will doubtless prefer a portable one, excellent varieties of which are to be fo'ind in most instrument shops. Electrodes, when in use, are distin- guished by the terms "positive" (anode) and "negative" (cathode), the former receiving its name from being attached to th(> first carbon, and the latter from its being attached to the last zinc of the battery. They are also distinguished by the terms, " internal " and " external,' according to the locality to which they are applied. Various forms of intra-uterine electrodes are in use. They are made of platinum, occasionally of copper or zinc, shaped like a Simpson's sound, c and so insulated as to expose r^—^ f\ orly a small portion of the £_ * distal end. The external, cutan- eous, or dispersing electrode is composed of a large, flat, con- ducting surface. There are several varieties. Apostoli uses moistened sculptor's clay; Engelman, a flexible plate of ,. ^ , , , . '' "'• 37 -iM.irlin s cutaneous electrode. lead, six by seven inches and Martin, a large concave plate, covered with a membrane and capable of containing warm water. This electrode is usually applied to the abdomen, sometimes to the back. By using large and wet electrodes, we chiefly get the interpolar effect, which is that of electrolysis. By using small and dry electrodes, we chiefly obtain the polar effect, 102 MEDICAL ANU SUIUUCAL GYNAECOLOGY. which, whi^ii the cunoiit is strong enough, bocomos chemical cnuterizntion. By combining largo wot oloctroch'H on the skin with small dry oloctrodos in the uterus, burning of the skin is avoided and chemical cauterization of the uterus obtained. The two poles of the battery have ditFerent physical and physiological effects. The positive pole attracts acids, while alkalies collect ut the negative; tli oschai" produced by the positive pole is dry, that by the nega- tive is softer and larger and allows the galvanic? current to penetrate througli it; the negative pole has a stimulating effect and will draw blood to the parts, the positive i)ole has a depressing, anti-congestive powiT, and will disixd it; the negative pole causes pain, the positive allays it; the positive pole has an escharotic drying effect, the negative a softening, liquefying effect. The Faradic current is produced by loading the electricity, generated in two or three Leclanche cells, through a short coil of coarse insulated copper wire, called the primary coil, in such a way that the current is broken and closed at short intervals. Outside the primary coil is another, called the secondary coil, which consists of a much longer and finer one of insulated copper wire. The current passing througli the primary coil is called the primary current, and that induced in the secondary coil, by means of the primary current, is called the secondary current. Both currents produce muscular contraction, but the secondary, producing the effect in a higher degree, is more generally used. With this current, in addition to the electrodes already mentioned, bipolar intra-uterine and vaginal electrodes are used by which the effects of the current are centralized. Practical application. Amenorrhooa of the functional type is one of the aft'ections in which we may hope for the greatest amount of good. Both the galvanic and the Faradic may be used alternately in this condition. Mild APPLICATION OF ELECTRIC CUKKENTS. lo;} gnlvniiio currents nv t best, from fifteen to rwenty nuUiani- peres. Tlie positive jjole is to be placed over the abdomen by means of the large electrode, r.nd if a virgin, the negative may l)e applied, by meaiiH of a smaller electrode, over the perineum, or if she Las borne chiLlron or is married, it is to be placed in the uterine cavity. For the application of the Faradic current the bipolar vaginal and intra-uterine elec- trodes may be used alternately. iSit-iior,,\,()ftli(' uterine candl, such as congenital pin-hole os externum, spasmodic contraction of the internal os, without ap- parent disease, stenosis due to sharp flexion forward or back- ward, are amenable to galvanic treatment. The negative pole is to be applied to the constricted part and the large positive pole to the abdomen for ten or iifteen minutes, with a powe" of fifteen to twenty milliamperes. Galvanism is also useful for almost every form of dijsmen- ovrluva. Here the best results will be attained by the introduction of the positive jwle within the uterus, because most painful menstrual states are attributable to congestion in that region. The mem- branous form yields better to curettage, but if galvanism is to be emi^loyed, the negative pole in the uterus gives the best results. In suhinvolntion, depending ujjon a low grade of in- flammation of the uterine tissue, in which the uterus has engorged vessels with inactive muscular structure and a Fk;. 38. — Apostoli's Bi-polar Ulcrine and Vaginal Kxcitors : i, small uterine ; 2, metlium uterine ", 3, large uterine ; 4, vaginal, used in the uterus after confinement. 104 MEDICAL AND SURGICAL GYNvECOLOUY. cortaiii amount of lymph thrown out, couKi(h'rnl)U' UHsist- ance may be obtaimnl from tho use of tho Faradic^ current; one pole in contaet with the cervix^ the other over tho ab'lominal or lumbar region. In mihintJolufioH, in connection with injuries (luring parturition, notably of the cervix, and in connection with tubal and ovarian diseases and pelvic exudates, the gal- vanic current, with t:ie negative pole within the uterus, must be utilized. Fifty or sixty milliamperes of this cur- rent, applied for fifteen or twi^nty minutes, twice a week, will soon soften the uterus and render it capable of absorbing, as well as promoting the absorption of patholo- gical products of long standing. EmIomHritis, In the simple catarrhal form, with hypersecretion of the uterine follicles, and from frequent repetition of which the uterus has become chronically eidarged, the Faradic coil will cause the organ to regain its tone, and its nutrition may be improved by frecjuent and mild applications of the galvanic current, the positive polo being intra-uterine. In the hemorrhagic, or fungous form, recourse is to be had also to the positive galvanic pole, seeking to bring it in contact with the entire surface. Fl<i>ifie <'.ifii(l(iti()ii. Good results often follow the adop- tion of this treatment in old parametric and i)erimetric exudates, but a careful diagnosis that pus is not present somewhere, must be made, before proceeding to its use. The positive ball electrode, covered with chamois or clay, is to be placed within the vagina and the largo electrode over the abdomen. Beginning at zero, the current is to be worked up to forty or tifty milliamijeres, and continued at that point for ten or fiteen minutes. The treatment is to be repeated twice a week. CdUirrluil S<ilj)lii</itis. The positive electrode is to bo pushed uj) as far as possible into the uterine cornu and a APl'LKJATION OP ELECTRIvJ CUKUIiNTS. 105 morlornto ".ilvniiic riurront of twonty to thirty millinm- peroK, for t 1 to fift(>(M) miiiutoH, tununl on. In elm <• rotujcxtiou of flic onirif, without dcciih'd (U'g(4uirntion, the poHitivo ball oUH!tro(le in to In* plmuMl in the vajifina or rectum, as near as possible to the eiihirjjjcd ovary, and a moderate curreni of ten to twenty inilliani- per(>s. for ten minutes, applied. Orai'ian (did pclric nciu'dhjia. There »ire eertaiu pains in the region of the ovaries and deep within the pelvis which are found difficult to associate with disease, but which are more likely samples of reflex neuralgia. In such cases electricity may be used to great advantage. First of all, use bipolar faradization with the tine wire coil, graduallv' increasing the strength, then changing to the coarser wire coil, until the parts either become benumbed or free from pain. Uterine jibroids. Before attempting electrical treat- ment in such cases, a positive diagnosis must be made of their position, whether sub-peritoneal, intra-mural, or sub-mucous, and of their quality, whether hard, or of the soft, cedematous variety. Snb-miirous pcdniicnldtcd Jihnu'ds will be benefited by the treatmeni, only by being forced out of the uterus, and care should be taken not to devote much attention to sub-peritoneal fibroids. Of the different varieties, the myo-fibromata are the ones for which the most good can be accomplished. Next in order stand the pure fibromata, but the durable effect, when once produced, will be the most marked in the fibromata. The first variety will require small amounts of galvanism frecjuently repeated, the latter will call for high intensities and short sittings. The application of galvanism to soft (vdcnudous tititiors should be avoided, as it often stimulates them to new growth, or promotes a tendency to break down into fluid spaces. 1 1 I ii 10() MEDICAL AND SURGICAL OYN.ECOLOOY. Fi'hi'o-cijstic tnniorn hImo forbid the use of tin? j^alvnnic current, on account of their poor vitality, and their liability to break down and produiie systemic poisoning. The cases reiK)rted, in which fibroid tumors art'^ said to have disappeared, are rari^ <u)nsi(lerinf^ the number tn^ated. In the lar^e majority tluTe is a p(^rceptible diminution in size which persists for a longer or shorter period. For the application of the j^alvanic current to uterine fibroids, the large flat electrode is placed over the abdomen and the intra-utc^rine pole to be used will (h^pend upon the results desired. The i)ositive pole is to be used when it is desired to affect the mucous membrane especially, and to arrest hemorrhage; the negative for electrolytic treatment. For the escharotic effect, thirty to fifty milliamperes during ten minutes and repeated a few times, will usually be sufficient. For electrolytic treatment the power is to be gradually increased up to the extreme limit which the patient will bear. Five to ten minutes will be sufficient, and the time for the repetition will b(> determined by observing the effect upon the tumor and upon the patient's general condition. Ectopic [fcsidtion. Both the Farad ic, and galvanic currents have been recommended to destroy the lift^ of the fcetus previous to the fourth month. With the iiresent knowledge of the extreme dangers surrountling ectopic gestation, increased often to their greatest intensity by even the slightest maniiiulation, it can scarcely be con- sidered safe to submit a patient to the manipulation necessary for the application of either current. Crtjliotomy is a much safer procedure, and consequently the use of the electric current can only be consideretl justifiable in localities far remote from skilled hands, or where removal or delay means grave danger, or in cases where ^he patient positively refuses to submit to ccDliotomy. PART TWO. FUNCTIONAL DISEASES. CHAPTER XII. DISORDERS OF MENSTRUATION. Abnormal changes in the menstrual flow are to be rc^nrdt'd only ah symptomH whieli linvi^ thoir origin often in opposite couditions and retpiire diHcrimination in their treatment. Tlie menstrual tiow may be absent (<n)i('H(>n'luv(() or scanty; it may be painful {(lijsnioi- orrlnvd) ; or it may be profuse {)iK'ii()rrlHt<ji(i). When the hemorrhage is profuse at other times than at the menstrual period, it is termed mciron'luuiia. AMEN()RRH(EA. Amenorrhoea, or absence of the menstrual discharge, is termed ])i'iniarij, when the patient has never men- struated, and secondary, when menstruation has previously occurred. Primarij (imenorrha'a may be divided into {a) prim- (irif pcrmdnciit amcnorrhivd, the most marked cases being those in which the ovaries, or uterus, or both, continue in a rudimentary condition, or are altogether absent, while the external genitals are normally formed, {h) Primary fcmporarij amcnorrJuva may be due to chlorosis occurring in girls under the age of puberty. Menstruation occurs later than normal, and, when it does set in, the flow is scanty and of short duration, (c) Delayed lyuherfy. Here the general and sexual development is complete, yet the girl fails to menstruate. It is often caused by over- work, combined with insuffirnent food, by change of 1()8 MliDIC'AL AND SUIUIIC'AL OYNEfOLOOY. {ilimiiti^ or luibitH ni about, the (<x[)'H't('(l [U'riod. or by too long coiiliiKMiuMit (luring acliool lioura, combined witli an ovor-taxt'd bra.'u. Sccomldi'ff (imcnon'h<v(( may b»' di.. to rormtitutional dcrangomiMits, as antomia, chloroHiH, diabi^toH, Hriglifn (liHt'aso, malaria, cancorouH carlicxia, tubi^rcudosiH, or acuto ilhu'HHCH. or i^ nuiy bo diu> to the intlucncc of tho norv.niH HyntiMU. Huoh as Hovore mental Hhoek. alarm or Huddtui fright, or by tho norvouH system generally being overtaxed. Among other causes may be mentioned obt^sity, change of climate, sea voyagi's, and sudden or prolongc^d exposure to cold, particularly at the menstrual periovl; or it may bo due to accjuired atrc^sia f)f the cervix, or of the vagina. Kemoval of both ovaries does not always lead to complete amenorrluua, some women (continuing to menstruate for years after their removal. There are ditt't^rent explanations given, among which may be mentioned, the existence of a supplementary ovary, by a portion of the ovary being left in tho pedicle, and by tho law of "persistence of habit." Symptoms. Besides the absence of the periodic flow, whi(ch is of course tho chief symptom, there are other symptoms to be taken into consideration, and which are for the most part tho.se of the primary disease causing it. When a case of amonorrluBa presents itself, it should detinitoly bo setthnl whether it is primary or secondary. Primary amenorrhom, in which the menstrual flow has never occurred, leads to questioning whether the uterus, tubes, and ovaries be present in their entirety. If present, it becomes necessary to ascertain whether atresia of the cervical canal, vagina, or vulva exists. If tho prodromic symptoms of a menstruation be absent, it points to con- genital deficiencies, but if the prodromic symptoms have been present, and repeated at lunar intervals, with no menstrual flow, suspicion of atresia is excited. If the case be one of secondary amenorrhoia, pregnancy and lactation must bo excluded. When arising suddenly, as for DISOUDEUa OF MENSTRI^VTION. im iiistaiico, from taking cold, huoIi HymptomH nn fovor, rnther Bovero ht>ft(Iu(On% paiiiH in tlu'^ back and pelviH and oxtiMul- in^ down tiw thij^liH, with irritability of tin- bladdt^r nnd bowels, ^oncrally appear. Diagnosis. Tlio most important <u)ndition from which it niuHt he (tan^fully dia^noHed is pn-^nancy, normal or ectopic. Evt^ry Hij^n of pre^nanc^y, parti(udarly tht^ early oncH, must be thought of and carefully brought to bear ui)ou the caHt\ Upon tluB point the prat^titioner must "Iwiys be on his guard. Designing women ofttMi consult .. physician for anuMiorrhoMi, when they know tlu^y are pregnant, hoping that something will be done to bring on their courses and thus interrujjt gestation. Treatment. Before any line of treatment can be satis- factorily establisluHl, a correct estimate of the symptoms must be madi^ and a conclusion arrived at, whether it is physiological or pathological. If the former, no treatment is needed; if the latter, the treatment will vary according to the special cause and must aim at the correction of the underlying morbid conditions. Hot hip and foot baths are generally useless, unless the function is about to appear. It is not uncommon for the menstrual function to be delayed for one or more years, or to be irregular, or 8usi)ende(l, for the first few years after its commencement, and hence no special remedy is needed, except attention to hygiene, diet, dress, exercise, and baths. The uterus, in such cases, being imperfectly developed, time must be allowed for its normal growth. Acute suppression, such as that arising from cold, is bost treated by rest in bed, a hot sitz bath every six hcurs, with a warm water vaginal douche at the same time, and by the administration of a laxative. Hot water bags applied to the abdomen and lumbar region, pediluvia with mustard and water assist frequently in giving r(^lief. The use of the so-called direct emraenagogues, as rue, savin, and cantharides, is objectionable. The uteriiu^ function should never be forced 110 MEDICAL AND SURGICAL GYNAECOLOGY. when the geuornl system is struggling for existence; besides very few remedies liave any direct stimulnting effect on the lining membrane of the uterus. Amenorrhcoa from malaria calls for the administration of qHiniiK' and change of climate. Rheumatic amenorrluua sometimes calls for the salicyldh')^. Ciniicifiu/d and (ina{(icu}ii are excellent remedies for rheumatic amenorrluxja, but espe- cially for delayed or painful menstruation. PnhatiUa is indicated when the menses have been stopped by mental shock or fright. Apiol is one of the most safe and efficient emmenagogues, and may be given in capsides containing five or six drops, three times a day, for a few days preceding the expected tlow. Aloes indirectly stimulates the internal genitalia, and is one of the best adjuvants to other treatmejit when con- stipation exists. Strijchnhic is a good muscle and nerve tonic, and will assist the action of iron. Lron is the hfBmatic tonic, and stands first. It has nn emmenagogue action, increasing the blood supply of the pelvic organs, and may be administered in any one of the recognized forms, such as the dried sulphate, the carbonate, the muriated tincture, either plain, or in the form of elixir or glycerole. The citrates, tartrates, lactates, peptonates, or other mild i)reparations are useful, but not so rapidly efficient. The therapeutic effect of any of these can often be improved by the combination of a small dose of liquor potassre arsenicalis or liquor arscnuci hydrochlor. Bland's pill, composed ci sulphate of iron and carbonate of potash, or the modified pill which contains arsenious acid as well, often gives excellent results. Among the various combinations the following are the most generally serviceable : R. Aloui, grs. xii; ]'il. Ferri Carb., drams isfir Myrrh, dnim ss; M« Ft. pil No. XL Sig. — Take two pills, three times a day, after meals. DISORDERS OF MENSTRUATION. Ill R. Ferri Siili)lmt., Exsiccat., grs. xl; Quiniii' Sulphat. , grs. xl; Strychnia' Sulphat.,gr. i; Ext. (ientian, q.s. M. Ft. pil No. XL. Sig. — Take one pill after tneala. R. Ferri Sulphat., dram i ; Pot<i8H. (!arb. , dram i; Quiniii' Sill, 'iat., dram 88 ; Ext. Nunc. Vom., grs. iv ; Aloin, grq. iv. Ft. pil No. XL. M. Sig. — Take one to two after meals. R. Tinct. Ferri Mur., drams v; Liq. Arson. Mur., dram i ; Acid Mur., C.P. dram i ; Sj'rup Simplicis, ad., oz. viii. M. Sig. — Dessertspoonful, in wine glass of water, after nteals. Pofdssium pcrmaiu/aiKitc or blnovidc of mam/aiicse sometimes verv efficnciou;?, when administered for a few days precediiij? menstruation, but the former often has a distressinjij eft'cot upon the stomach.. The k)cal usi^ of electricity is the most reliabhi of all emmenagogues, being the most direct \iterine stimulant we possess. It is well adapted to stubborn, long continued cases, which have resisted hygienic and medicinal treatment, more particu- larly when the uterus has been found small and ill- developed, or has been atrophied from superinvolution or chronic metritis, or in cases in which the internal genitalia have been found markedly dormant and atonic. Vicarious menstruation is a condition closely allied to amenorrluea. It means a condition of the female system in which there is a regularly recurring discharge of blood from other par' of the body besides the uterus. The sanguineous flow may come from tlu^ nose, bron- chial tubes, stomach, intestines, or rectum; generally it comes from a mucous siirface, but it may take place from the skin or at the site of a wound. The treatment applicable is that adapted for ameuorrhoaa. 112 MEDICAL AND SURGICAL GYNECOLOGY. MENNORRHAGIA AND METRORRHAGIA. The first of these two words is usod to oxpross nn excessive menstruation ; the second, for n flow of blood not only nt the menstrual time but between menstruntions. Neither condition is a disease, but a symptom of some well-defined pathological '■ ^udition. Women vary greatly within the physiological limits in the amount, the dura- tion, and the frequency of menstruation, and it is thus difficult sometimes to say where normal menstruation ceases and menorrhagia begins. Menorrhagia may occur as an excessive flow of blood during the normal numbi^r of days, or an ordinary flow extending over an excessive number of days, Causes. Hemorrhage associated with abortion, myo- matous degeneration of the chorion, placenta previa, retained membranes, and the like, are not to be considered as having a place under this heading. Women of hemorragic diathesis bleed more freely at the menstrual epochs. Hremophilia, scrobutus, and purpura act in the same way. Chlorosis, as a general thing, tends to amenorrhcea, but in some cases it leads to menorrhagia and metrorrhagia. Many other conditions dispose to it, as long-continued mental depression and other nervous disturbances, luxurious living and sedentary habits, resi- dence in tropical climates, malaria, tubercle, the acute exanthemata, lead and phosphorus poisoning, and Brlght's disease. It may be associated with disorders of the circulation, such as mitral incompetence or stenosis; congestion, from any cause, of the portal circulation; renal or splenic disease; abdominal tumors, or even overloaded bowels. The chief local pelvic causes are ovarian, uterine, and peri- uterine congestions and inflammations; tubal inflammatory diseases; the earlier stages of chronic metritis; subinvolu- tion; chronic endometritis; cervical lacerations; diplace- ments; uterine fibroids and polypi. DISORDERS OF MENSTRUATION. • 118 One of the most common onuses is the jirosence of fungositios within the uterine oivity; and malignant diseiises of the uterus is nhnost invariably followed by menorrhagia and metrorrhagia. Many women firmly believe that the menopause must be attended by an excessive menstrual flow. Such is not the case; after thti menopause has once been established, post-climateric hemorrhages are almost invariably due to a local lesion, such as senile catarrh, cancer, or the presence of mucous or fibrous polypi. Tr('((f)ii('nf. The treatment of menorrhagia resolves itself into that aijpropriate for the attack, and that for the menstrual interval. Rest in bed, in the recumbent position, should be insisted on, light non-stimulating diet, the — ictum unloaded and the bowels kept open. Chronic jnstipation, particul- "ly when associated with congestion of the portal circulation, is to be overcome by a pill of podophyllin and nux vomica at night, followed, in the morning, by a teaspoonful of some saline, such as effer- vescing granular phosphate of soda, or a wineglassful of Hunyadi Janos water. The medicinal hemostatics to be used must d(>pend ui)on the provoking cause. In moderate, persistent, erratic hemorrhage, particularly where the fault lies in the heart's action, or in a retarded venous circulation, (lij/itdli)^ is one of the best remedies. It operates by increasing the arterial tension and thus improves the atonic circulation. Enjot is singularly well adapted to conditions of the uterus in which there are well developed, but relaxed muscular fibres, with dilated and engorged blood vi^ssi^ls. The more soft, flabby, relaxed and engorged with blood the uterus is, the more pronounced will be its effects, hence it is partic- ularly indi(!ated in chronic hypenemia, active or passive; in chroiiic metritis, in its first stage, and in subinvolution. Hiimamclis, in the form of fluid extract, is a most usi^ful remedy. For sudden outbursts and for active and profuse 114 MEDICAL AND SURGICAL GYNAECOLOGY. hemorrhage it is inferior to c^rgot, b\it for n slow long continuous flux, or hemorrhngo pnssivo in chnracter, it is the remedy j)a?' excellence. The fluid extract of ergot and hamamelis make an efficacious combination. Hydrastis Canndeiisis is a vaso-constrictor in congested states of relaxed mucous membrane and for uterine hemorrhage, due to endometritis, myomata, or incomplete involution, it is very valuable. It also combines well with ergot. A neat way of administering is in the form of hijdt'dstine, given by the mouth or hypodermatically in a ten per cent, solution. The following combinations have been found very serviceable : R. (•allic acid, dram i; Ergot, Fluid Extract, oz. ss; Acid Sulph. Aromat, drams iiss; Elixir Simplicip, ad., oz. viii. M. Sig. — A table«{>oonful in some water every four hours. R. Ergot, Fluid Extract, oz. ss; Hamamelis, Fluid Extract, drams iii; Tinct. Hyoscyam, drams iiss; Elixir (Jentian Co., oz. i; A(juas ad., oz. viii. M. Sig. — A tablespoonful in some water three times a day after meals. Thicfure I)i()if(dis, drams iiss, may be combined with either of these, should the indications call for it. The action of medicinal agents should be supplemented in severe cases by local applications. Hot water may be injected into the vagina, and when the patient has become deeply aniemic from loss of blood, normal salt solution may be injected into the rectum. The best non- operative means is the vaginal tampon. The vagina and cervix may be tamponed with absorbent cotton after the hot water irrigation and allowed to remain there for twenty-four hours. During the intervals, the judicious and thorough use of the currette is one of the best means of promptly and safely curing many of these cases. Local galvanization of the uterus is a therapeutic agent worthy of the highest consideration in uterine DISORDERS OF MENSTRUATION. 115 hemorrlingo (loppiidont upon uterine fibroids nnd chronic nfpections of the endometrium. Faulty conditions of the blood from niiiinnin, chlorosis, or defective hygiene, are to receive special care. Iron, in the form of the nniridtrd fiiicfurc, forms an excellent means for checking excessive menstruation dependent upon marked annemia; however, in most causes it is to be utilized only daring the mens- trual interval. Arsenic is a most valuable hemostatic in the menorrhagic conditions of young girls, as well as of women nearing the menopause. At such times, if too profiise, too frequent, or continues too long, it is best met by administering threi^ to five drops of liquor potassse arseuicalis three times a day. It seems to be indicated when iron is contra-indicated, and may be given during the time of the flow as well as during the interval. A generally favorite prescription is known as the combination of the sulphates. R. Magnesia' Siilpli., dniins vi; Qiiiniii' 8ulph., grs. xxv; , Ferri Sulph. Exsiccat, grs. xl; Acid Sulph. Aroinafc. , drams iis.s; Acjua Mentha' Pip., ad., oz. viii. M. Sig. — A tablespoonful in a wineghi.ssof water after meals. R. Pulv. Ferri Redact., grs. xl; Quiniie Sulph., grs. xl; Acid Arseniosi, grs. i; Extract (ientian., (js. M. Ft. pil No. yh. Sig. — One pill after each meal. Precocious menstruation is a regular lunar flow of blood from the genitals every four weeks, occurring in children below the age of puberty. As a rule, both the external and interal genitals and the breasts are abnor- mally developed in such children, and sometimes they show sexual appetite. Nothing can be done for them except to keep up their strength, and such other treatment as will make uj} for the loss of blood, until they have reached the proper period. lift MEDICAL AND SURGICAL OYN.EC()L()GY. DYSMENORRH(EA. Dysmenorrhcea means difficult or obstructed men- struation. It is one of the most common of the various menstrual deranfj^ements, and manifests itself by pain, which varies greatly as to frequency, duration, time aud severity. It may properly be divided into the following varieties: — The ncuvdlf/ic, the rofUfCfit ire or injUimmaiovji, the ohstnictivc, and the mcmhrcmous. To this classifica- tion the ovdvlan has been added by some authorities. It differs from the others more in location than in kind, and it can scarcely be said to deserve recognition st^parate from the inflammatory. Spasmodic dysmenorrhcea is a term applied to the neuralgic form, in which there is spasm of the circular fibres about the os internum. Neuralgic dysmenorrhcea. This variety does not depend upon any appreciable organic disorder of the uterus or of its appendages. Ordinarily, on the most careful physical exploration, no alteration in size, shape, position, consistency, or vascularity of the pelvic organs or structures will be noticed. The sentient nerves of the endometrium appear to be in a state of hyi^eraisthesia — a neuralgia in the ordinary sense of the term. Cduscs. There are many agencies which, at times, so alter the healthy state of the nerves as at one time will produce a gastralgia, at another an occipital or facial neuralgia, and similarly in neuralgic dysmenorrhooa there is present a local neurotic state, provoked to the excita- tion of pain by the stimulus of the physiological congestion incident to the oncoming menstruation. The causes which generally induce it are: The neuralgic diathesis, hysteria, chlorosis or plethora, malaria, gout, rheumatism, luxurious and enervating habits, and habits deteriorating the ner- vous system. Symptoms. It is by far the most frequent variety, and is found oftenest in those who are subject to the various DISORDERS OF MENSTRUATION. 117 neurotic discnses. The pain mny show itself before the flow hns been established and disappi^ar as soon as it comes on, or may continue with varying intensity throuj^li- out the duration of the menstrual discharge. The pain is located in the uterine or ovarian regions and radiates towards the iliac, abdominal, lumbar, or sacral region, or down the thighs. The discharge may be scanty or profuse, and the severity of the pain seems to bo in inverse propor- tion to the quantity of the flow. The diagnosis is made by the exclusion of the other varieties. The pain felt in the uterus has nothing expulsive in its character, the flow is steady and not interrupted, no clots are discharged by spasmodic efforts, and physical examination discovers no obstruction. These facts will distinguish it from obstruc- tive dysmenorrhoea. It is differentiated from the conges- tive form by the absence of constitutional disturbance and by its being habitual and not exceptional, by the absence of the ordinary signs of endometritis and of ovarian and pori-uterine inflammations. The trcdtmcnt resolves itself into that which is appro- priate for the time of the flow, to relieve pain, and that for the interval, to remove the cause and prevent its repetition. If the rheumatic or . gouty diathesis *>xists, it may be combated by administering half dram doses of the ammoniated tincture of guaiacum. by twenty drop doses of the wine of colchicum, or by Ave t'^ ten grains of soda salicylate, three times a day. In amemic and neurasthenic cases ferriagineous and nerve tonics such as iron, nux vomica, phosphorus, quinine, cod liver oil, malt extracts, and the hypophosphites should be given, and the strictes*^ attention to general hygiene observed. If plethoric, a strict plain dietary should be demanded, and administra- tion of such purgatives and saline medicines as will favor the portal circulation and deplete the system generally. Malarial toxeemia should be treated by quinine and change of residence. A sea voyage will often accomplish 118 MEDICAL AND SURGICAL GYN.ECOLOdY. excellent rosults. Local fnrmliziition with the secondary current in UHefu!, but often the bcBt rcHults are to be obtaintul from the galvanic, with the positive i)ole intra- utiirine. For relief at the menstrual pt^riod tlu^ use of opium and cldoral should be forbidden, except under extreme necessity. Phenacetint> in five to ten grain doses often gives almost immediate relief. Tincture of cannabis indica, in doses of ten to fifteen drops every four liours while the pain is severe, is also beneficial, and should be tried before resorting to opium or chloral. Apiol. in five drop capsules, given three tinu^s a day for a f(^w days before the flow is expi'cted and continued mon^ often during the fiow, has done excellent service, especially in the amenorrluvic forms of dysmenorriuua. Tincture of Pulsatilla, given three times a day for at least three days preceding the painful period, is indicated in the neurotic types of the disease, especially in young women. Tincture of cimicifuga. given three times a day during the whole interval and more fre([U(uitly at the menstrual period, is useful in the neuralgic and rheumatic forms. Viburnum prunifolium, in the form of fluid extract, often gives good results when administered in half dram doses for a few (lays before the exijected period and continued during it. This treatment may be supplemented by hot vaginal douches and the introduction of one-fourth grain sup- positories of extract of b(>lladonna. Congestive or inflammatory dysmenorrhi^a. At each menstrual period an active congestion occurs in the mucous membrane of the Fallopian tubes and uterus, as well as in the ovaries, and probably to a less degree in the pelvic tissues. When any abnormal influence renders this excessive, it naturally produces pain in the nerves lying between the distended vessels. This excessive hypericmia, which may result from a mechanical cause, as a displacement of the uterus, or from a vital cause, as the peculiar condition which we know as inflammation, gives DISORDERS OF MENSTRUATION. U\) rise to n vnrioty of painful inouHtruaticu which has boeu styled congostivo or inHammatory. Causes. In a groat many cases inHanimation of the uterine mueou.^ membrane is the cause of this form of (lysmenorrluDa. The existence of disease in this part causes perhaps little pain until aroused by menstruation. It may result, however, from almost any i)elvic inflamma- tion which alters the condition of the m^rves immedialely affected by ovulation or menstruation, or from any c luse which exaggerat(>s and prolongs the congestion excited by ovulation. Chief among these may be mentioned general pk>thora, exposure to cold and moisture, sudden mental disturbance, disturbed portal circulation, displacements of the uterus, fibroids of the uterus, areolar hyperplasia, endometritis, pelvic cellulitis, and peritonitis. Si/mplonis. The patient, who has previously men- struated painlessly, is seized during a period with severe pelvic pain, accompanied by di munition or cessation of the discharge and considerable constitutional disturbance. The pulse becomes full and rapid, the skin hot and dry, and with these there is headache, nervousness and restlessness, and occasionally rectal and vesical tenesmus. In cases in which a local inflammation exists, when the flow begins or before that time, the patient suffers from dull, heavy, fixed pelvic pain, which lasts until the process is ended, and even afterwards. If it be due to hypenemia, the suddenness and constitutional disturbancew will mark its difference from the neuralgic and obstructive form, and if it be due to the influence of existing pelvic inflammation, it will usiially be marked by jjain during the inter-menstrual periods, by difficult locomotion, fatigue after exertion, leucorrhoea, and such like. Treatment. As in the neuralgic form, the source of the trouble must be sought for and combated along the lines laid down for the treatment of that particular form of disease. General or local plethora must be relieved, 120 MEDICAL AND SURCUCAL (iYN/Ct'OLOGY. (liHplntHMnoiitH and versions ovorcom(% and if niiy lociil iiiHamination bo diHooveriMl, it should hv tlio subjoct of trontmcnt. Should the fittnc-k bo nccidoutal nud duo to hypi^raMnin moroly, as from oxi)OHuro to cold and nioisturo, the patient had better be put to bed, hot applications applied over the hypogastric and lumbar rofjfioiiK, and a hot vaginal douche administorod every four hours. A saline pur^e is to be ^iven, and a febrifuge mixture com- posed of the following administered: R. Tinct. Aconit., dram 88; Liciuor Ammonia! Acefcatin, o/.. 188; Spirit .'Ether, Nit., drums v; Atjuii', ad., oz. iv. M. Sig. — Uessertsjwonful in Home water every two liourw. The pain may be relieved by phonacetino or by small repeated doses of Dover's powder. Should local inflammatory conditions be discovered to bo the cause of the dysmenorrhfea, a small cotton tampon, impregnated with boro-glycorido, with or without the addition of a few drops of fluid extract of belladonna, and inserted behind the uterus, will often give marked relief. A five per cent, solution of ichthyol in glycerine applied in the same way will act in a similar manner. Local applications of heat and vaginal douches will also act as valuable adjuvants. The internal administration of bromide of ammonia, or of tincture of cannabis indica, combined with liipior ammonia acotatis, spirits of ammonia aromat and peppermint water, will have a decided soilntivo effect, and tend to relieve the congested state. R. Ammonia' Bromid., oz. ss; S[)t8. Ammoniiv Aromat, oz. i ; Li(|. Ammoniiu Acet !. i ; Aqua> Menth. Pip., oz. viii. M. • Sig. — Table.spoonful in some water every four hours. Obstructive dysmenorrhoea. If after the blood has collected in the uterine cavity any obstruction exists to prevent its escape into and through the vagina, sijasmodic pains are excited which often amount to uterine tenesmus, DlSOUbEUS OF MENbTUUATiON. 121 and (irc^ very Himilar to the (WpulHivi^ paiiiH xHuirrinjjf (luring iioriiml labor. To tliiH form of painful uumi- struatiou tin* name obHtriuitivi^ (lyHnuMiorrluua \uxh boon applied. The obHtruction may exist in tho corvix or os, in the vagina, or at the vulva. The special raiiscs of obstructive dysmenorrhcua aro con^^enital or acciuin^d contraction of the cervical canal, such as is found in the elongated and (lonoid infra-vaginnl cervix, with pin-holo os, or that form arising from chronic intlammation, especially inrtammation resulting from the vicious use of strong caustics. Flexions of the uterus, especially wlien the angle formed is sharp, will produce it, more particularly when associated with version. Vaginal stricture, either congenital or acquired, will prevent the free escape of blood and produ<!e uterine tenesmus, and in like manner the hymen may produce the same effect. Sometimes a small polypus comes down to the os internum and resting upon it, acts upon the principle of the ball valve, and by so doing produces the worst features of obstructive dysnienorrluua. A fibroid in the parenchyma of the cervix, by producing tortuosity of its canal, will cause a similar effect. The s///«7>/o;».s are characteristic. After menstruation has continued for some hours, and sufficient blood has collected in the uterus to distend it, a spasmodic pain occurs in the jK^lvis, increasing into a more or less violent expulsive eft'ort, like the contractions attending a mis- carriage. This, in time, causes the passage of a certain amount of blood, the pain then ceases and the patient is relieved, until further distension and obstruction occurs, when the process by which the uterus empties itsel'; is repeated. These symptoms are so marked and decided that little difficulty will be experienced in a diagnosis, but before a decision is arrived at, a careful physical iwamin- ation should be made, to discover the cause and thus place the matter beyond doubt. 122 MEDICAL AND Sl'lU;iCAL UYN-ECOLOOY. Trcdttiiciit. Till' ln>Ht rccoj^iii/t'd trcatmciitof onlinary cftH(^H of iu'rvi(Mil o()iiKtri(^ti()n, wlu'thcr u('([uirc(l or con- j^i'iiital, is (lilutHtloii by incanH of j^radiiatcd dilators, or more fonribly by iiu^aiiH of (loodi'lTH or some otluT nivrl dilator. Wlu'ii the conHtrictioii docK not cxiKt within tlio ciTvicMd (^anal. it in usually tlio rcKult of Homo Ht'vrro intiammation following; tlu^ uh(^ of caustics, or of a (u»rvical laceration, and in such (^ascs it may be found ninu'ssary to lay opiMi the oh by cutting with a knife or wussors. Tn order to keep the cervix or os patulous, the dilators may be introdu<^ed from time to tinu\ but the method is painful and often unsatisfactory. The difficulty may be overcome by at onci> inserting a glass or aluminum intra-uteriiui stem pessary and rt^taining it in place by means of tampons friupiently changed, or better, by a Thomas' cup pessary, allowing the pessary to be worn for two or three months. The intra-uterine stem pessary is the best method of treatment, after the canal has been straightt^ned, for constriction arising from flexion. Obstruction, arising from vagitml stricture or obturator hymen, may be ov(^r- come by dilatation or incision. Polypi and submucous fibroids in the cervix are to be at once removed. Membranous dysmenorrhcea. This variety consists in the exinilsion from the uterine cavity at menstrual periods, of organized material, which is found to consist of structures resembling the lining membrane of the uterus. It may consist of a sac representing the triangular cavity of the body of the uterus, with its three openings, or it may come away piecemeal, in shreds, or as strips of mucous membrane. When more or less complete it is soft, comparatively tliK-k, and with many perforations, the sites of the utricular follicles. Under the microscope the cast is found to consist of the lining membrane of the uterus hypertrophied in all its elements, almost exactly as in pregnancy, lieMice it has been termed " menstrual decidua." There are many views held as to its etiology, DIS'.UUEUS OF MENSTRUATION. 123 l)ut the two nmin oiu>h nrc, first, tliat it \h an exfoliation of the entire nuK^ouH membrane of the uterine body (hi(> to irritation transniitted to it, the rt'Hult of some ovarian (list'ase. This view is tho one most fre([ia ntly accepted. Second, that it is an exudation, thrown out ovi^r tiio ut(>rini^ wall, the result of endometritis, and tH)nstitutinj^ a caste of the uterine cavity. Membranous dysmenorrho^a may be confoundi'd with early abortion, blood casts or fibrinous moulds of the Fn;. 3g. — A Dysmenorrhtual Membrane laid open. ■ uterus, or with exfoliation of the vaginal mucous membrane. From the first of these, the differentiation may be accom- plished by the progress of the case, the repetition of tho pr- ^ess, and the caitire absence of the symptoms of l^regnancy, wliile tiie microscope will show the absence of villi of the chorion and of tho large irregular decidua cells. Blood clots and vaginnl exfoliations will also be readily recognised by the microscope. Sij)iij>t(niiii. With the commencement of the menstrual flow there are steady pains which iucrense as it progresses I 124 MEDICAL AND SURGICAL aYN//COLt)GY. until tlioy become violent nnd expulsive, like those of abortion. Under these the os gradually dilates and the membrane is forced out into the vagina. Tlu^re is commonly a tendency to menorrhagia, which however, soon disappears, but for some tim(^ after it has passed off there are symptoms of endometritis and purulent and sanguineo-purulent discharges. Trcafnioit. The uncertainty of the i)athology of this disorder has led to a great variety of treatment. For the pain which attends the attack, a hypodermatic of morphia may have to be administered, and occasionally the pain is so severe as to demand the administration of a little chloroform or sulphuric ether, particularly when morphia is not well tolei-ated. Hot applications and vaginal douches, so useful in all forms of dysmenorrluua, are also ai)plicable here. If uterine or ovarian disease be detected, it should bo treated in accordance with general rules. The largest number of cases successfully treati'd has followed repeated dilatation and curetting cf the uterus, in conjunction with applications of chloride of zinc or carbolic acid, and packing with iodoform gauze. This line of treatment may alternate with galvanization, ten to twenty milliami)en^s, the negative pole intra-uterine. All varieties of constitutional treatment have been tried and abandoned. Ovarian Dysmenorrhcea. In a number of cases, by no means small, no disordered condition of the nervous system will be found to account for habitual dysmen- orrlnua, and exploration of the pelvis will fail to discover uterine or peri-uterine disorders. By a careful bimanual examination in such cases, a globular slightly compressed mass, abo\it the size of a walnut or small egg, will often be found in Douglas' cul-de-sac, or or one or both sides of the uterus, low down and in close proximity to it. These are the ovaries, enlarged, tender, prolapsed, and revealing a condition known as chronic ovaritis. The pain in this DISORDERS OF MENSTRUATION. 125 form of dysmenorrlujoa precedes the flow by several days and diminishes as it is established. It is of a dull character, extends over the nates, down the thighs, and is particularly liable to be accompanied by nervous mani- festations and depression of spirits. The breasts often sympathize, becoming painful to the touch. It must not however be supposed that in all cases of enlarged, tender, or prolapsed ovaries, ovarian dysmenorrhoea will be found, nor in every case of ovarian dysmenorrhoea that the ovaries will be found in tliis condition. Tlie trcdtnirnf of this class of cases is perhaps the least satisfactory of all classes of dysmenorrhcea. In a young girl, in whom ovarian disorder has advanced only to congestion, recovery may rapidly take place, but in a woman further advanced hi life, and in whom chronic enlargement of the ovaries has occurred, associated with tenderness and prolapse, the prospects for cure are slight. Sterility in tliese cases is the rule. It is just in .such conditions that bad habits are to be contracted by the use of alcohol, morphia, cldoral, or chloroform, and their administration should be avoided as much as possible. Hot applications, warm sitz baths, and warm soothing vaginal injections should be employed. Internally there is no remedy so efficacious as the bromides — tiai grains of bromide of ammonia or soda every four hours, commenced a few days before tlie fion' and co^itinued until its close. For the immediate relief of pain, phenacetine, exalgine, cannabis indica, or monobromate of camplior may be employed. Locally, in addition to the hot applications and douches, a boro-glyceride tampon, impregnated with a few drops of fluid extract of belladonna and inser<^'^d behind the uterus, soothes and relieves the local irritation and congestion. When unmistakeable evidences of organic ovarian disease exist, the operation for the removal of one or both ovaries is advised as the only means of giving relief. 126 MEDICAL AND SURGICAL GYNiECOLOGl. In treating the subject of dysmenorrhoea, all the Vftrioties generally indicated by autlioriti(^s have been included, because, by the adoption of this method, a more thorough investigation of the subject is secured, and a recollecticn of them at the bedside will often aid in the classification and treatment. It must not, however, be supposed that every case of dysmenorrhoea will be sub- jected to strict limitations, on the contrary, many, if not most cases, give evidence of one or more disturbing elements. As for instance, a retroversion occurring in a weak' nervous woman with impoverished blood might cause a dysmenorrhoea, due in part to mechanical obstruc- tion, in part to neuralgia, in part to congestion, and, perhaps to some extent, to a secondary endometritis. In view of this fact, it is well to have in memory somt^ general plan of treatment which may be resorted to in cases not readily susceptible of classification. Hot wet or dry applications to the abdomen and lumbar region, hot vaginal douches, and rectal enemata have a place in the treatment of every form. Medicated vaginal tampons and suppositories aid in allaying congestion, in soothing the pain, and in supporting the uterus and adnexa, and may safely be used in almost every case. The administration of a saline jjurgative will empty the bowels and relieve portal or pelvic congestion; and for the relief of pain and as a sedative to the nervous system, a judicious selection from the drugs already referred to will oftcMi accomplish much of the desired effect. STERILITY. 127 CHAPTER XIII. STERILITY, NYMPHOMANIA, VAGINISMUS, LEUCORRH(EA. Sterility is nnothor functioiml disorder of the uterus, and implies an inability for impregnation during normal reproductive life. It is sometimes coiKjcnitdl, the result of faulty development. It is said to be cicquircd when it arises from disease after an uncertain period of fertility. A marriage may be unfruitful from causes pertaining to the male or to the female. More women than men are sterile, in the proportion of six to one. Impregnation becomes impossible from absence or a very incomplete development of the vagina; from atresia of the vagina, or from an imperforate hymen. Sterility may occur from a condition of the vulvar orifice, called vagiiusmus, in which all attempts at coition cause extreme suffering (dyspareunia), the sphincter vagiiiie and muscles of the pelvic floor being, at the same time, thrown into a spas- modic state. It may arise from inability of the semen to enter the uterine cavity owing to atresia or stenosis of the OS, or to flexions, displacements, or tumors of the uterus. The vitality of the sperm may be destroyed by excessive acidity of the vaginal mucous. There may be incapacity for proper ovulation, which includes any condition of the ovary which impairs the ovule, such as chronic ovaritis and cystic degeneration; from impt^rfect development of the ovule, the result of debilitating diseases as amemia, scrofula, tuberculosis or syphilis. Gonorrhoea, it matters not how contracted, is a very common cause. Sterility may be owing to organic changes in the Fallopian tubes, which prevents the safe passage of the ovum through them; to pelvic peritonitis, which prevents an instinc- tive application of the fimbrire to the ovaries; to inability, after fecundation, to continue gestation; or, finally, to want of physical adaptation of the parties, " sexual incom- 128 MEDICAL AND SUROICAL GYNAECOLOGY. patability." Mnrried life may bo sterile for years, yet when either party obtains a new companion fertility may follow. Treatment. While judicious treatment occasionally gives favorable results, it often terminates in disappoi it- ment. Success in the managt^ment of sterility depends largely upon a correct diagnosis, and the special I'atment of all varieties consists in the riunoval of the cause, if practicable. In all cases of long-continued sterility, after having thoroughly examined the female without finding a satisfactory cause, investigation should commence with the male. If the uterus is absent or small, less than an inch or an inch an a half in length, all efforts to ensures fertility would seem hopeless. An ill developed uterus may be stimulated to growth if the patient is young and healthy. Excessive acidity of the vagina may be overcome by the use of alkaline waters internally, and by v .ginal injections of weak solutions of carbonate of potash prior to coitus. Nymphomania. When the sexual feeling in the female is excessive or perverted it is called nymphomania. There is a mental perversion, attended by an uncon- trollable sexual passion, which, in its most severe form, is often associated with or dc^pendcnt upon certain varieties of insanity with or without gross brain disease. Although observed in children and octogiuiarians, it occurs most frequently at the beginning and at the end of men- strual life. There is the greatest perversion of the sexual act, gratification being sought not oidy in masturbation, but also with others of the same sex. In many instances the disorder is a reflex manifestation arising from irrita- tion of the genital organs, or from certain diseases of the uterus and appendages. The exciting causes may have their origin in the intestines, especially in the rectum, such as by the presence of worms or hemorrhoids. Inflam- mation of the vulva, vagina, urethra, bladder, or the NYMPHOMANIA, VAGINISMUS, LEUCORRHCEA. 129 irritntiou of diabctio urine may give rise to it. Nymplio- maiiin inny also result from freciueut masturbation as well as cause it. Treatment. The best results are obtained by moral suasion. Occupation of the mind and free physical exercise in the open air, early rising, cold bathing, regularity of the bowels, a plain non-stimulating diet, and the internal administration of the bromides, are the best remedies. When local disease is suspected, it is to be sought for and treated. Clitoridectomy and oorphorectomy have been tried and have failed to effect a cure, and such operations are indicated only when incurable disease of the external genitals or ovaries respectively perpetuate the condition. Vaginismus. Vaginismus consists of hyperajsthesia of the vulvo-vaginal orifice and neighboring parts, accom- ])anied by abnormal and painful contraction of the muscles of the pelvic floor. It is not a disease in itself, but a symptom of various morbid conditions of the vulva, vagina and the surrounding parts, among which may be mentioned urethral caruncle, erosion, inflammations or fissures of the vulva or hymen, rectal fissures, cervical lacerations, and uterine and ovarian displacements. Tri'dtumit. The cause of the local irritation is to be removed and the general health improved. Gradual dilataticni may be practised by introducing a series of dilators, a larger dilator being used and allowed to remain for a longer period each succeeding day. Forcible dilatation, under an ana^stlietic, may be practised, after which a good sized glass or hard rubber dilator is to be inserted and allowed to remain for several hours. LEUC()RUH(EA. By the term leucorrhoea is meant a " white flow," but, in the ordinary acceptation, it is used to designate any discharge, other than blood, coming from the genitals, 130 MEDICAL AND SURGICAL GYN/ECOLOGY. although nt times the leucorrlioeal discharge may have a sanious admixture. In its normal condition tlu^ genital tract is just moist enough to be soft and well lubricated. For a day or two after menstruation many women have a slight increase of moisture, but any decided increase, whether mucous, senms, or purulent, is abnormal and constitutes in itself, if not a disease, a symptom of one, and one often of much importance. The discharge may come from the vulva, the vagina, the cervix, or the interior of the uterus. It may be colorless, white, yellow, green, red, or brown. It may be nearly as thin as water, or more or less thick, like cream or soft cheese. Leucorrhoea may be idioixithic or stjniptotiiafic. It is called idiopathic when it is not traceable to any definite disease, or patho- logical condition, or to any permanent structural anatomi- cal lesion. It is found often in young and anaemic girls, in those of sedentary habits, or in those whose employ- ment compels them to remain standing upon their feet for hours. It may be induced by anything that weaktnis the constitution, such as protracted lactation, bodily or mental fatigue, emotions, especially of a depressing kind, and is often found in persons predispt)sed to uulmonary phthisis. Like other catarrhal affections, it nay be due to exposure, or to residence in a damp climate; or it may be induced by local irritation, such as masturbation or frequent coition; or it may appear in consequence of amenorrhoea or scanty menstruation. Si/iiipfoiiis. Apart from the discharge, which, as a general thing, is of a whitish color as it appears at the vulva, there are often other leading symptoms. The patient is often auipmic, has a pale, worn, tired, or pinched look, and a feeling of general weakness. The appetite is poor and the digestion impaired, giving rise to flatulence and gastralgia or enteralgia; constipation and an irritable bladder are frequently present. Backache is a character- istic symptom. The patient complains of a dull heavy LEUCORUHCEA. 131 pnin over the sacrnl region, or at the tip of tlie ooccyx, whioli may be continuous or may be brought about by long standing or other fatigue. Trcdtment. From the symptoms described it will be readily seen that general and local treatmiuit must go hand in hand. The more the condition depends on constitutional causes, the more general must be the treat- ment. Strict attention must be paid to general hj'^giene. Plain substantial food that the stomacii can readily digest must be taken, and the bowels kept open by some mild aperient, such as a pill of aloin, strychnine and belladonna. Tonics, particularly the ferrugineous and ni^rve tonics, are here indicated, and an emulsion of cod liver oil is often well borne, helping to liuild up the system. Such inti^rnal remedi(^s as hydrastis and cimicifuga seem to have the special virtue of checking leuchorrluua. Warm hip or tepid general baths are to be recommended, and night and morning a vaginal douche of hot water, followed immediat(^ly by a warm astringent solution, may be used. In many cases treatment carried out on these lines will suffice to effect a cure, and is especially to be tried in intact girls, before resorting to or suggesting a physical examination. Symptomatic leucorrhoea. Leucorrhom is a symptom of numerous local diseases of the genitals, suc^h as vulvitis, vaginitis, specific or otherwise; endometritis; metritis; subinvolution ; erosion of the os ; lacerated cervix ; polypi ; fibroids, or carcinoma. When even a mild leucorrlntial discharge has resisted treatment for a considerable length of time, or in cases in which the amount of discharge, or its color or consistency, points to the ijresence of a local disease, no time should be lost in making an examination, and in treating the cause according to the pathological conditions found to be the chief factors in the production of the loucorrhcoa. PART THREE. DISEASES OF SPECIAL REGIONS. CHAPTER XIV. DISEASES OF THE VULVA. Malformations. 1. Absence of the vulva. By nu arrest of developmont in tho first mouth of foitnl life, the external genitals and nnus may be absent, the skin covering the region uninterruptedly. If the nnus is formed life may be continued without the external genitals, the urine being evacuated through the navel. 2. Hi)i)(Hi})(t(li((S. In consequence of insufficient clos- ure in the median line, the lower wall of the urethra may be split more or less deeply. If the defect extends very deeply so as to divide the different sphincters of the urethra the patient cannot retain the urine. 3. Episjxidids is characterized by a lack of union of the upper wall of the urethra. It is generally combined with a similar defect in the anterior wall of the bladder (extroversion). Epispadias, like hypospadias, has been cured by plastic operation, such as stitching together flaps derived from the mucous membrane of the vestibule, or by uniting two lateral denuded surfaces in front of the open urethra. 4. The clitoris is sometimes split in two lateral halves, with or without cleavage of the urethra. It may be absent, or very small, or, on the other hand, as large as a medium sized ixniis. 5. The prepuce is frequently adherent to the glans, and in many cases this condition gives rise to reflex neuroses and even epilepsy and nymphomania. DISEASES OF THE VTLVA. I'iili (). The l<tl>i<i miiioni may b(^ ahsoif, or it may bo mnUi'itIc, each being Hplit lengthwise in two or three flaps. 7. The hihid, nuijovd may likewise be split by longi- tudinal ch^fts, or may extend so far back ns to reach behind tiie anus so that there is no apparent perineum. 8. Hcmdphnxlisni. By this term is meant a congenital malformation of the sexual organs, in which the germinal gland of each sex (testicle in the male and ovary in the female) is found in one and the same individual, together with mori^ or less perfect organs belonging to both sexes. Anatomically and clinically it may be divided into two chief varieties, the true and the .'^/>?^•/o/^s•. or pHciulo- hcnuiplirodinm. True hemaphrodisni may be divided into three forms: bilaieml, in which an ovary and a testicle are found on each side; unihiteraJ, in which an ovary or a testicle is found on one side, and on the other both an ovary and a testicle; and hiferal, in which an ovary is found on one side and a testicle on the other. Fseudo- henidphrodism is that condition in which the sc^xual glands belong to one sex, either masculine or feminine, while the passages leading from them, as well ns the external parts, approach more or less the other. There are two great varieties of this malformation, Andnuftpie, in which a man simulates a woman both in the general conformation and local appearance of his sexual organs; and (jt/aitdrid, the far less frequent condition, in which a woman simulates a man, the resemblance being confined almost entirely to the external sexual organs. The clitoris is elongated two or three inches and possessed of more or less erectility, and perhaps the labia partially united so as to have the appearance of a scrotum. Tiie diagnosis of the sex is often difficult. A periodical bloody discharge has even been observed to take place from apparently normal male genitals, especially from males suffering from hypospadias. IJU MEDK^AL AND SUR(JICAL OYN/ECOLOOY. Tlu* fi'caliiiciif in pnuiticnlly nil. A liyiJOHjHidino un>tlini may bo ri>Htoro(l, n blind vaj^iiml poiu^li (doHod, but usually nothing can ho dono to restoro the partH to tluur normal Htato. A liyp('rtroi)Iii('d (ditoris Kliould, of courH«.% bo romovcd. Hernia. Two kindn of liorina find tlioir way into tho labia majora, tlio (inferior or iiii/Kiiio-lahidl and tho f^oxtcrior or rfajino-lahitd. Tho in(ffii)i(>-l(ihi(il, or that kind corrospoiuling to an inguiiud hernia in tho malo, in not uncommon. Tho hornia comos out throujfh tho inguinal (wuuil, follows tho round ligament, and tl(>s(U'nds into tho anterior part of tho labium niajus. Tt may contain intestine, a portion of tho mesentery or omentum, an ovary, the bladder, or even tho entire uterus. It may be mistaken for a tumor of the round ligament or a hydrocele, or for an abscess, cyst, or tumor in the labium, but bj'^ paying att(>ntion to the general rules laid down in tho surgery of hernia a diagnosis may be readily made. Trcdfrncnf. A properly fitting truss will very often give the required relief, but the wearing of it is occasionally uncomfortable or irksome to the patient. This class of hornia is particularly suitable for what is commonly known as tho radicxil opcratiou, and Bassini s method, modified so as to apply to the female inguinal canal, is very readily performed and gives excellent results. In cases where the opening is large or direct, buried silkworm sutures, uniting the conjoined tendon with the deep i^art of Poupart's ligament, will give the necessary and -permanent support, acting in the same manner as silk worm sutures when buried in the aponeurosis, after CGiliotomy, to prevent ventral hernia. Va<lino-l(ibi(il is a much rarer form of hernia. The escaping abdominal viscera descend in front of the uterus, along the vagina and bladder, between them aiul the levator ani muscle, and form a swelling at the posterior DISEASliS OF Tllli VULVA. 135 (mhI of tli(< lahiimi tnnjiiH. It uHimlly contni h n part of till' Hiimll iritcHtiric. Troihticnf. It is ditfiiMilt to hold this form of luTiiia back, but, aH it may bccomii very lar^v tho attempt h1iou1(1 be madt' with vaginal iM^HHarioH or iiitlatablc rubber ba^H. Hydrocele cousiHts in a colhu^tion of tiuid iu that pjirt of tho routid ligament wliic^h lies in or below tlu> iuj^uiiuil canal. Thin Huid may be (-oiitaiiied in the proiu'SH of peritoneum which at times surrounds the ligament outside the internal inj^uinal ring (canal of Nuck), and in this way may communit^ate with the ab(h)minal cavity; it may bo in the surrounding connective tissue, or in the liga- ment itself. Great care should be observed in making a diagnosis of this rare malady. The sensi> of fluctuation, with entire abseiu^e of symptoms of iiiHamnuition. tlu^ absence of resonance on percussion or other signs of hernia, the existence of translucency, and the gradual development of the tumor without pain or constitutioiuil excitement, \k'ould be reasons for suspecting it. Trciihucni. It is unsafe to inject these tumors, the same as in the nmle, on account of the uncertainty of the diagnosis. By open incision the diagnosis may be properly made and appropriate treatment i)ursued. The incision is made over tlu^ tumor iu its long axis, the sac opened and the contents carefully examined. After the fluid has been evacuated the wall may be touched over with strong carbolic acid, the cavity packed with iodoform gauze and allowe i to heal by granulation. Should the sac communi- cate with the general peritoneal cavity, it shouUI be drawn down and closed off by a circular catgut ligature, or by one if the methods recommended for the radical cure of hernia. Haematocele of the canal of Nuck and haematoma of the round ligament are ev(m more rare than hydrocele. The former consists of a collection of blood within the process of peritoneum, and the latter in the interior of the L% MEDICAL AND SURGIC\L QYN/ECOLOOY. round lij^amciit, nn tlu^y lit^ in tin* hiKuiiml canal. Tliry may b(» dia^iioHi'd from intoHtiiial lu-rnia by tlic poiiitn ri'ferrod to wluui Hpcakhig of liydrocelo, and from lirrida of tho ovnry by its immobility and abHonce of Hensitivc- ncHH. The trontmi'ut couHiHts in makinj^ an incision into it, turning out tho contontH and packing with iodoform gaU 7A\ Injuries. Tho vulva may bo tho scat of bruiHos or wounds in conHocpKuico of a fall upon some blunt or sharp instrument, or from blows or kicks, which, if slight, readily respond to ordinary treatment. Sliouhl tlu^ injury bo so localized or of such violence as to injure tho reticulated plexus of large veins, known as tlie bulbs of tho vestibule, on(^ of two effects will be produced. If there be corres- ponding rupture of tho skin a free and sometimes alarming hemorrhage will occur, known as pudenddl lu'morrlKiyc. If the skin remains intact, the blood pouring out into the areolar tissue surrounding tho wounded plexus will soon form a (\oagulum, constituting a bloody tumor which has received tho name of pmlcniUil luriiKifocch'. Cduscs. Tho j)r<'(lisj><tsin(/ cduscs are pregnancy, varicose condition of tho veins, and largo pelvic tumors; the oxciting causes are muscular efforts, blows, or incised or i)unctured wounds. In pudcMidal hemorrhage a physical oxamiimtion will at once reveal the condition, and the control of the How will not bo difficult if managed on the general i)rinciplos laid down for the treatment of hem- orrhage. The clotted blood which forms a pudendal ' ^Mnatocele may occupy the tissue of one labium or tho ar tissue immediately surrounding tho wall of the <ina. When a considerable sized vessel has been raptured tho tumor may reach tho size of an orange; at other times it is quite small, perhaps not larger than a walnut. Care must be observed not to confound it with abscess, pudendal hernia, inflammation of the vulvo- vaginal glands, or oedema. The physical characteristics, DISEASES OF THE Vl'LVA. 137 niodi^ of (l(>v(»lof)m('(it. and ratioiml hIj^iik of hucIi affcctionH nro HO (liffcmiit from i)U(lcii(lal liu'inatorrli' that a careful oxainiiiatioii will always scttk* tlu- [)oitit with certainty. Xntnral ronrm' (iftrt'fnnndfioii. Should the tumor bo left to itself, it may bo absorbed in a short time; in five or six days it may burst and discharge; the clot may become encysted and remain in(letinit(>ly; or it may creatt^ suppurative inflammation and formation of an abscess. Trcdfnicnf. A small tumor may be let alone, or treated V ith a cooling astrinj^ent or absorbent application. When the tumor is large, or experiment has demonstrated that it will not undergo absorption, it is advisable to make an incision into it antl evacuate the cont(>nts. If bleeding points appear they may be securcnl by forcipressur(>, and the cavity afterwards i)acked with iodoform gauze. When the cavity is large, or the hemorrhage abundant, buried catgut sutun^s may bo inserted through the walls of the tumor so as to include the veins from which the hem- orrhage occurs. After approximation of the walls by these ligatures, and a gauze drain introduced, super- ficial sutures may be inserted in the marginal mucous membrane. As soon as pus is formed, whether largo or small, it must at once be evacuated, the cavity carefully washed out with bicldoride SC' ition and drained with strips of iodoform gauze. Phlegmonous inflammation. The areolar tissue of the labia raajora is frequeiitly the seat of inflammation and abscess. The disease is excited by irritating vaginal secretions, vulvitis, direct injury, ami the peculiar blood state which results in the development of furuncles and carbuncles. Didf/nosis. It is usually easy to distinguish this disease, but care must be taken to diagnose it from hernia of the intestine or ovary, and from haimatocole. ojdema, and vulvitis. The ordinary symptoms of inflammation 138 MEDICAL AND SURGICAL GYNAECOLOGY. and tlu> ox(iuisit(^ sensitiveness of the swelling will servo as a valuable aid. Treatment. The first stag(> is best managed by cold sed- ative and astringent applications, such as acetate of lead and opium lotion. If suppuration is inevitable it should be met by hot fomentations and hot bio^'loride absorbent cotton poultic(>s. Early evacuation of the pus as possible, is advisable, becausi^ the tissues obstinately resist natural evacuation^ and the accumulation of pus is liktly to point in another direction. Cysts and abscesses of the vulvo-vaginal glands. The long exert tory ducts of these glands, situated on each side of the ostium vagiuiu between the vagina and the ascending branch of the ischium, sometimes become occluded by adhesive inflammation arising from acrid dischargi^s, from the presence of pruritis from other irritating causes. As a result, the secretion of these glands is retained; they undergo great enlargement and distension with or without preliminary formation of a cyst; suppurative inflammation may be sot up and abscess result. Diajjiiosis. When cystic distension exists, the locality of the round or ovoid mass rolling slightly under the finger, without tenderness, will assist in making a diag- nosis. Pudendal hernia and hydrocele of the round ligament are two important conditions from which they must be diagnosed. Hernia is reduceable and gives a distinct impulse when the patient is requested to cough, and it does not feel so elastic as in the case of cysts. Cysts grow slowly, the percussion sound is dull, whereas the appearance of a hernia is rather sudden and, if an enterocele, is resonant on percussion. When inflammation has been set up there are the usual symptoms present, the mouth of the duct is red. and the fing(>r press(>d over the site of the gland will discover a hard, painful, and perhaps fluctuating tumor, about the size of a small hen's egg. It DISEASES OF THE VULVA. 139 may bo known from plilej^inonous inflnmma^^ion of the liibinin by its distinct globular and liniitod outlines the t'ornuT affection bc^in^ diffuHc. Trcdfnicitf. The cyst mav be incised within tlie free edge of the hibiuni and, afte. vacuation of the contents, the sac wii)ed out with tincture of iodine or a ten per cent, solution of (chloride of .Jnc, and then i^acked with iodoform ^auze. It is desirable to remove a portion of the sac wall after having incised the cyst. This operation, although tedious, is certain in its results, and is the best to follow under ordinary circumstances. The total removal of the cyst is often a difficult and sometimes bloody operation, and hatl bc^tter not be attmnptt^d, unless prepared for such emergencies. Pozzi recommends, after withdrawing the contents, to distend the sac with warm paratine, and whe.i hardened, to dissect the whole mass out. After the removal of the sac, by whatever method employed, the cavity is closed by a deep row of sutures placed through the edges of the wound and passing down through the bottom of the cavity, and a second row placed at iialf the depth. After insertion they are to be tied in the order in which they were placed. When inflammation sets in, it is to be treated in the same way as for abscess of the labia, and as soon as fluctuation is distinct the pus should be evacuated by a long incision, the cavity irrigated with bichloride solution and drained with iodoform gauze. Tumors. The vulva is subject to the formation of n variety of tumors. The condjilonKifa acnmlnafa or pn})iUom<d<i may be due to gonorrheal irritation, or simply to the hypenemia and discharge from the parts occurring during a vulvo-vaginitis or normal pregnancy. They are found chiefly on the labia minora, or at the posterior commissure, and may extend more or less deeply into the vagina. The coiKli/lomafa hit<i, occurring on the iiisidi' of the labia maiora, on the perineum, or around the anus, are 14:0 MEDICAL AND SURGICAL GYN/ECOLOGY. always due to syphilitic infection. The treatment of the acuminate and pajiilloinatous varieties consists in cutting them off witli curvt'd scissors, and touching their bases with caustic or with the actual cauti^ry; or they may be effectually removed by puncture with the negative electro- lytic needle. Compresses soaked in the tincture of tliuga occidentalis mixed with equal parts of water will, in some cases, cause atrophy of these growths. Liponid have their origin either in the labiiim majus or in the mons veneris. They are rare, but when they occur, sometimes attain large dimensions. Mjioma, Jihronui, myxoma, and miral (/roii^fliH have their origin ordinarily in the labium majus. Their tendency is to grow in the direction of the least resistance, and lience it is not unusual for them to bec^ome peduncu- lated, and sometimes they reach as low as the knees. The treatment of these tumors is surgical and, when operated upon with care, is devoid of danger. ElcplKUiti'dsiis vulv(V. This disease, seldom seen in this country, may affect the entire vulva or only part of it. Its location is generally on the labia majora. the clitoris, and the nymplia\ Histologically, several varieties of this disease occvr, but they have all one element in common, namely, a change in the lymphatic cir- culation, the lymph vessels being dilated and indurated from the beginning. They have their origin from repeated attacks of lymphangitis, which ultimately result in hyper- plasia of the entire derma and subcutaneous connective tissue. When inflammatory changes with new forma- tions occur first in the papilhv*. the tumor strongly resembles the large coalescing condylomata. The large tumors are liable to extensive ulceration from local irritation, and the warty forms may undiu'go malignant degeneration. Tn'((tiii('iif. All medicinal treatment has thus far failed; the same may be said of the galvanic current, the only rational one being surgical. DISEASES OF THE VULVA. 141 Lupus, sarcoma and cancer are fortunately rare. Thoy occur usually upon the labia minora or majora and spread thence in various directions. The prognosis of cancer, which is usually of the epitheliomatous variety, is unfavorable, unless seen very early and completely extir- pated. Sarcoma presents itself as a tumor springin^j^ from either the labia majora, the labia minora, or the clitoris, and is diagnosed mainly by its rapid growth and soft fe(4. In cases of difficult diagnosis, resort should always bo made to the microscope. Neuromata are of more frequent occurrence, and are either situated about tlie meatus or clitoris, or at the posterior commissure. They are usually nodules, not larger than a pea or bean, and exquisitely sensitive to the touch. They should be removed by thorough deep incision with scalpel or scissors. Varicose tumors. Such tumors may occur in the vulva as the result of pressure from a pathological or physiological growth in the pelvis. The distended veins are readily recogni/.ed, and can hardly be mistaken for any other condition. In most cases they are connected with pregixancy, but may occur independently of it. They may burst spontaneously and if the skin holds, a hiematoma is formed. If the! skin breaks, a serious if not fatal hemorrhage may follow, especially when associated with pregnancy, at which time they are often of large size. Uretliral caruncle. Just at the edge of the meatus urinarius, and sometimes along its wall for some distance, little vascular tumors develop which render the c^anal very irritable. They consist of hypertrophied papillfi\ are extremely vascular, and are richly supplied with nerve filaments, facts which account for two corresponding clinical observations, nanu^ly, that they bleed very freely and readily, and that they are almost as sensitive to the touch as a neuroma. 142 MEDICAL AND SURGICAL GYNECOLOGY. Sijmf)foms. Tho patient complains of pain, accom- paniod often with hemorrhage during sexual inti^rcourse, in passing urine, in walking, or by contact of the clothing. Inspection shows at the meatus a florid vascular growth, varying in size from that of a cherry stone to that of a pigeon's egg. Sometimes, instead of one, quite a number may be found of small size extending around the meatiis. Care must be taken not to confound it with prolapsus urc^thne. Treatment. In single large caruncles an almost posi- tive promise of relief may be held out from its removal by means of the thermo-cautery. When a number of small fungous growths surround the meatus and extend up the urethra, cure is extremely difficult, as after their removal the morbid process rapidly produces more. When the urethra has been invaded it should be thoroughly stretched and the growths brought into view, when they may be removed by scissors, or scraped from their attachments by a curette, after which their bases should be touched by the thfmo-cautery. Special attention should be paid to any disordered condition of the urine or disease of the bladder. The nervous hyperi^sthesia engendered during the growth of these tumors is apt to continue, and an irritable condition of the urethra and neck of the bladder are likely to follow for some time after their removal, hence it is well to notify the patient of these probabilities. Urethval venous (iiKjionia is a disease affecting the urethro-vaginal tubercle, and occasionally the urethro- vaginal wall. It sometimes attains a large size and pro- jects between the labia. Absence of sensitiveness will diagnose it from urethral caruncle, which it closely resembles in apptmrance, but the treatmtnit is Identical with that condition. Prolapsus urethrse. This accident consists, when acute, of prolapse of the urethral mucous membrane alone, but if it is of long standing there will be in ad- DISEASES OP THE VULVA. 143 (litiou n i^roliferntion of tho uuderlyinpf coniioctivo tissue. It is not nil uncommon condition, and may exist for some time without symptoms, but usually it creates difficult and painful micturition, pruritis vuIvjb and leucorrhceal dis- charge. It may be confounded with urethral caruncle and venous angioma, but can be recognis(ul by remember- ing that it produces a projection which completely encircles the meatus, while the former do so only in part. Neither pain nor hemorrhage can be depeniled upon for diagnosis, as prolapse may develop such symptoms very dcicidedly. Treat me nf. Acute cases may be treated by replacing the protruding mass, and by the subsequent application of hot wati>r, by rest in bed ani^ by efforts to previ^nt rectal and vesical tenesmus during the evacuation of these organs. Tannic acid, or other astringent bougies, may be introdiiced into tiie urethra. These means failing, recourse may be had to linear cauterization of the pro- lapsed membrane by means of the thermo-cautery. Ex- cision of the redundant tissue is frequently necessary and. after removal witli the knife or scissors, the urethral mucous miMubrane should be stitched to the margin of the oritice with tine sutures. VULVITIS. Vulvitis is the name applied to inflammation of tho skin and mucous membrane covering the vulva. It appears in three different forms, simple, pHrident, and follienlar. To this chissiflcation there has been added by some, the i>lil<>(/iii(>ii(ms, venereal, and (/aiijirenoKs forms. Simple vulvitis is by far the most common form of inflammation. It is usually produced l)y the irritation of acrid vaginal discharges, by the pn^sence of pediculi, or by pruritis. The secretions from the inflamed surfaces are usually of a serous, non-purulent character. The diaf/nosis is made by the red eroded appearance of the 144 MEDICAL AND SURGICAL GYNECOLOGY. vulva, which often exttmds down to the anus and to both nates, especially in stout women. Purulent vulvitis. This variety of the aft'ectiou may be either a non-specific form or a true gonorrluea. It may result from simple vulvitis, specific or simple vagiuitis» uncleanliness, friction from exorcise, erui)tive disorders, onanism, chemical irritants, or excessive venery. Difupiosis. The parts are red, swoHon, hot, and at first dry, but soon a free flow of pus takes place whicli bathes the whole surface. In addition to thes'? signs of active inflammation, superficial ulcers will be found scattered over the parts att't^cted, and at times th>> inflam- mation will extend to the submucous and subcutaneous connective tissue, producing abscesses { ph!<'<))it()Hoiis vulvitis), and in rare cases patches of membrane will be seen adhering to them {(liplithcritic vulvitis). The glands of Bartholin may be involved, leading to suppuration and tlie formation of abscess. At times tlu' meatus uriiiarius becomes affected, prodncing a reddish margin around it, accompanied by* painful micturition, and a sensaticni of heat and s(;alding. The pus which is discharged, ^^speci- ally when specific, gives forth a disagrec^able odor, and is exceedingly irritating when brought into contact with other parts. Follicular vulvitis. By this form of vulvitis is meant inflammation of the muciparous, sebaceous, and piliferous glands. In ordinary purulent vulvitis these, as component parts of the diseased membrane, are implicated in the morbid action, but sometimes the glands alone are affected by disease, when the name follicular vulvitis or vulvar folliculitis has boon applied. The causes are about the same as those of purulent vulvitis, and the general symptoms those of local inflammation, but it is diagnosed by the peculiar appearance it gives to the vulva, the labia majora and minora being studded with small round red protuberances, from the size of a millet seed to that of a DISEASES OF THE VULVA. 145 hemp seed. Ofton n hnir comoH out from tho middle of one of these elevatiouB, and from the opeuiufj; n drop of pus may be pressed out. As a rule the inflamed follicle bursts, and shrivels up, but exceptionally the disease ends in induration and the production of small hard nodules, DifKjnosis. The signs and symptoms are usually clear enough, nevertheless it is sometimes difficult to distinguish one variety from the other. It is especially important, but often impossible, to determine whether the in- flammation present be of a gonorrluual nature or not. Th^^ history of the case is generally wanting or mis- leading, but the following features may be looked upon as important, not only in making a diagnosis of gonorrhuial vulvitis, but of gonorrlnual infection in organs beyonil : A purulent discharge in the absence of ulceration, erosion, or malignant disease, associ- ated with inflammation of the urethral orifice, and two bright red spots mark- ing the orifice of the ducts of Bartholin's glands (macula gonorrlueica); warty condylomata complicated with folli- cular vaginitis; salpingo-perimetritis; sudden development of infiammatory disea.se of the genital organs in a newly married woman, which injunvs her healtli to a degree out of all proportion to tlie local condition; habitual aborti(m; sterility acquired after the birth of one child; ophthalmia neonatorum; and especially the detection of the gono- coccus. Fin. 40. — FoUiciil.ir Vulvitis. 146 MEDICAL AND SURdlOAL OYN;ECOLOGY. Trndniciif. Propliylaxis consists in scrupulous ch^nn- liiicss niid in tlio prcvt' itioii m\d removal of cvt^ry cftusc liki^ly to pro(luct> it. In schools and institutions, it is of jjjrcat importance that tach person should have her own basin and towel. Sponges, as far as possible, are to be avoided; certainly they shoidd not bo used in common. In acute vulvitis the paiient slumld bo confintHl to bed and the diet of a li^bt unstimulating character. She shoulil sit for Hftel^n miiiuti's in a warm hip bath, to which has boon added bi carbonate of soda or permang- anate of potash, and after this a compress wet with liquor jjlumbi subacetatis dilute, or a solution of boric acid (2 per cent), or of salicy'ic acid (1 to (i(XX)). appli(5d frecpiently. In tlu^ mon^ chronic form, astringent and antiseptic applications will also he requin^d, such as solutions of acetate of lead and opium, tannin, carbolic acid (1 to (>0), sulphate of copper (1 per cent), corrosive sublimate (1 to .'{aX)). In chronic cases, particularly in the intertrigo of fat women, dusting powdt^rs will bo found useful: R. Boric acid, zinc oxid., aa. drams ii ; Pulv. aiiiyii, drama iv ; Pulv. rad. iridis Horeiitiiui', oz. i. M. Ointments are indispensable in some cases, especially when the surface has to be protected; R. Zinc oxid., drams ii ; Carbolic acid, dram ss ; Va.seliii alb., oz. ii. M. If there be much local irritation, thymol (2 per cent), or cocaine (5 per cent), may be added. In follicular vulvitis the pustules should be opened and the parts fomented with an antiseptic compress. In acute inflammation of Bartholin's glands, a warm sub- limate compress should be constantly applii^d and, as soon as the absci^ss shows any tendency to point, it should be freely opened, well washed out and draininl with iodoform gauze. DISEASES OP THE VULVA. 147 There is a vnrioty of vulvitis wliieh 1ms boon styled (/(iHjircnoux. It bogins on the vulva as a white blister which soon changt^H to an uleer; it nc^xt asHumeH a diphtheritica aspect and becomes gangrenous. It is a disease, however, almost entirt^ly confined to children. Eruptive diseases. The skin and mucous membrane making up the vulva may, like the same structures in other parts, be affected by eruptive disorders of various kinds. Tln^ following will include thosc^ most commonly met with: rnir{(/(> presents large scattered pai>ules, very irrita- ing, and generally have their apices bereft of cuticle. Liclirn shows more numerous papules resting upon a thickened and somewhat indurated cutaneous base. For such conditions the use of one of the following formuhe often proves very serviceable : R. Menthol, flrams ii ; 01. OlivH', dniins iv ; Chloroform, (hum i ; Lunoliiii, oz. ii. M. Ft. ungueiitiim. R. Acid Salicyl, dram s« ; (Jreosote, gtt. xl ; (ilycerini Amyli, oz. ili ; Ltinoliiii, o/. i. M. Ft. uiif^uentum. Eczema producers a red heated surface, covered with little vesicles which, breaking down, give forth a serous fluid. Sometimes there are successive crops of vesicles, and in many cases of diabetes and vesico-vaginal fistula ; this affection constitutes an exceedingly annoying and even painful complication. In the acute stage, cold or warm compresses and subacetate of lead lotions are generally all that is needed. When the discharge is profuse and watery the surface should be powdered. In more chronic cases Hebra's unguentum diachylum, white precipitate ointment (grs. xx. to oz.), or the following, will often prove very serviceable: I 148; MEDIdAL AND SUimiCJAL GYN^ECOLOOY. 11. Boric acid, drain i ; ' I Mil I lib. acot. , {ffH. X ; BiHtuiitli. .siibiiit, dram i ; VaHcliii alb., oz. i. M. Ft. iiiif,'iioiit. The vulvn mny also bn tho scat of acnr, cri/thona, aiul n'ifsijK'his, but as thc^Hc diHi-asi^H ottVr nothing piHuiliar in this region tlioy aro to bo treated tho samo as in otht^r parts. Herpes pro(iciiit(i lis iH a mild inflammatory aff'oction, consisting, as it doos in other parts, of vosiolos, or a group of vesicles upon an inflamed base, their appoaraneo being preceded by a burning and it(!hing sensation. Tho vesicles soon rupture and form scabs or shallow ulcers, each the size of a single vc^sicle. Sonu^tinu^s it is accom- panied with much (inlema of the vulva and may lead to enlarg(^ment of one or more of the inguinal glands. It may be confounded with a cihancre in tho erosive stage, but that has a deep, dull rod, ooj^jpory color, and its floor is smooth and shiny, without the small granulations foend in herpes. This disease is also apt to be confounded with exr/ema, but tho latter has a tendency to spread at the edgi^s, herpc^s appearing in successive crops. In tho early stage a cooling sedative lotion will give much rolicsf, and tho following ointment may be applied: R. Menthol, drum i ; 01. Olivii', drams iii ; Bismutli. Hubiiit, drams ii ; Lanolihi, o/. ii. M. Ft. unguent. Pruritis Vulvae. This affection consists in irritability of the nerves supplying the vulva which induces tho most intense itching, and desire to scratch and rub the parts. At first tho irritability and tendency to scratch aro slight and give little annoyance, but tho disorder is aggravated by the counter-irritation which it demands for its relief. Tho itching is so extreme that it irresistibly drives tho patient to scratch herself, anil by constant DISEA8EH OF THE VULVA. 14'.) ropctition the nkin boromcs torulor, its iutvor HPnHitiv(>, cxcorintioiiH and intlnmiiuitory coiiditioiis follow, all of which conirihuti' to the morbid condilioii. The misery produced ill Hiu^h (mihch cannot be I'xa^^erated; tlu' i)atient Ih tormented night and day, WKrioty be(!omeH dintaHti^ful to lier. and nhe j^ivoH way to dcHpondency and di^jn^Hsion. The itt^iing iH j^enernlly intermittc^nt, in some (rawos <)c(Mirrinj^ at nij^ht, and in others only at ct^rtain periods of tlu^ day. It is not always confined to the vulvn, the irritation often (extending up the vagina, to tlu^ anus, and down th(^ thighs. Tlu^ pn^disposing causes nn\ uterine, vaginal or urethral disease; pregnancy; liabits of indolence, luxury or vi(u^; unch^aidiness; or over-exercise in one of sedentary habits. In nearly ev(^ry instance of pruritis one of the following conditions will b(* found to exist as i\\v ap[)arent cause at U^ast: (/ontact of irritating dlst^harges, such as from acute and chronic tMidometritis and vaginitis, from the discharge of cancer, from incon- tinence of urine, or from diabetes; local intiammation, as vulvitis, urethritis, or vaginitis; local irritation, as eruptions of the vulva, animal parasites, f)nanism, vt^geta- tions oTi th(> vulva, or vascular urethral c^aruncles. How- ever produced, very soon secondary influences arisiiig from excoriations, ulcerations, increased discharges, the result of scratching, superadd themselves as auxiliary agents and keep up the disorder. ■ Trcdfimmt. The first effort must be made to discover the disease of which the pruritis is a symptom, and remove it by appropriate means. But this alone will not be sufficient, for, while eradication of the mischief is being attempted, palliative means must be vigorously adopted for the sake of i^resent relief. Perfect cleanliness should be secured by means of three or four sitz baths daily and the vagina syringed with pure or medicated water. The irritated surfaces should be protected by unctious sub- stances or inert powders, such as bismuth or zinc oxide, lt«! 150 MEliU'AL ANU SUKOICAL UYNJiCULOUy. combiiiod with lycoiKMlium or stureh. In cnm^ tlio (IIh- clmr^c* conu'H from tht^ utc^ruH, uftcr a thorough viij^iiiul (louflic, tlu' ii|t|)('r (>ii(l oF tlu' vaj^iiui slh)ul(l hv tanipoiu'il with cotton luoiHtt'iu'd witli ii wt>ak Huj^arof lead or horairic; Holutioii. If it is thci roHuit of a hx^al iiitiaininatioii it Hhould bo trt^atod as olHowliorc rcoomiiuMidw! for such conditions. Tcnipo'-ary ndi(^f (^an be obtained by covering the parts with a lotion composed of the following: R. Plumb, licet., (Irainn Ihh ; Afitl Carbolic, dram i ; Tiii(!t. Opii, o/. i ; A(iii!i' ad., oz. xvi. M. R. Hydra;;, bichlor., grs. xvi ; Tiiict. Opii, oz. i ; Atjuji' ad., oz. xvi. M. Relief may also be obtained by a strong solution of bromide of potash, or by painting the parts several times a day with glycerine mixed with chloroform or acid hydro- vjyan. dil. (1 to 8), or with morphim^ (3 grs. to the oz.), or at longer intervals with a ten per cent acpieous solution of cootane. Ointments often give markc^d relief, such as: R. Chloral. Camphor, aa., drum i; Vawolin alb., oz. ii. M. R. Aciid hydrocyan. dil., ilrams ii; I'lumbi acet., grs. xl ; Olei cacao, oz. ii. M. R. Acid Tannic, dram ss; Kxt. Belladonna', grs. x ; Va.'ielin, oz. ii. M. Hyperaesthesia of the vulva consists in an excessive sensibility of the nerves supplying the mucous membrane of some portion of the vulva. Sometimes it is confined to the vestibule, at others to one labium majus, at others to the meatus, while at other times they may all be simul- taneously affected. It is not a true neuralgia, but an abnormal sensitiveness of the nerves. There is no inflam- matory action and examination reveals nothing; the slightest friction, however, excites pain and nervousness and any degree of pressure is absolutely intolerable. The DISEASliS (IF Tllli VULVA. 151 (liHonlcr is comparatively rare and the trcatniout of it moHt iinsatisfactory. even coinijlctc {l^Htnictiou of tlio mucous uicmhrani^ of the Hcusitivi^ area with caustics, or its removal with tlu' knife, has failed to [)roduce a pernianetit cure. Kraurosis vulvae is a diseast' .-harai^teri/ed by a pet^uliar atrophic shriiikiu;^ of the intt^j^umentH of the tvxternnl genitals and perineum, ri^sultiiig in the oblitera- tion of the normal folds. Tlu* tissues att'cu'tinl beconu* dry, shrink, lose* their normal elasticity and become so brittle tiuit tiu^ most (direful examiiuition may cause dei^p fissure. Tlu* surfaci* assumes a whitish, maceratt^d, shiinn^ nppenrance. This disease does iu)t yield to any rimKul} . Coccygodynia. UiuU^r this name are united different and i)artially unknown patholo^^ical (H)uditions. thi> com- mon feature of wliic^h is intense pain at the coccyx, wheiu!o it may radiatt* into the periiuMim, hips, uterus, or bladder. Sonu'tinu'H there are palpable diseases or deformitit^s of tlu* coccyx, such as caries, ankyh)sis. luxation, or abnormal length. At other times it is combined with disease of the uterus, ovaries, or rectum, whiU> in a third class it is of a l)ur(*ly luniralgic nature. It is usually found in women who have borne children, but it occurs alst) in virgins. . It often appears after ted'ous labor, accompanied by rupture and straining of tlu muscles nnd ligaments. It may bo due to violence from without, as from kicks, falls, or other injuries, while sometimes it appears to be due to a reflex neurosis. Severe pain is felt on sitting, and it may be so great that the patient can sit only on one half ^f the nates, near the edge of the chair, and the jjain is aggra- vated in sitting down or getting up. The condition is easily recognized by introducing the index fiager into the rectum, while the thumb rests on the skin over the coccyx. The slightest movement causes severe pain and f ometimes it may be possible to feel the diseased coiulition of the bone. 152 MEDKiAL AND SURGICAL GYN.ECOLOGY. Trcdfmnit. B(>foro any plan of troatmi^nt is adopted care nuist bo tnki'ii to discovc^r wlicthcr the disorder is secondary to uterine diseas(> or anal Hssure. Ifsnt^h should be the easi% thi' primary disordt^rs and not thi^ir results shoidd receive attention. If the disease be primary, blisteriiij^. hypodermatic injections of morphia and the persistent use of the galvanic current will often effect a cure. While they are bein^ employed, tliree grain iodoform rectal suppositories may be used, together with general treat- ment to improve the nervous system. Sliouhl these means do no good, resort must be had to one of the radical methods for cure. The first operation consists in making an incision down upon the coccyx, lifting the exposed extremity of this bone, and then with a pair of scissors severing the muscles. It has been recommended to perform the operation subcutaneously, with an ordinary tenotomy knife, but it is by no means so easy a matter as one would suppose, besides, open incision clears up any doubt there may be in the diagnosis and, if found necessary, leads to the performance of the second method, which consists of the complete severance of all attach- ments, and the removal of the whole coccj^x, by a pair of bone forceps, or by disarticulation with the kni'le. CHAPTER XV. LESIONS OF THE PELVIC FLOOR. The pelvic floor, also known by the somewlnit in- definite name of perineum, comprises the tissues which together occupy the space between the bones of the jielvic i)utlet. It is composed of a pair of broad thin muscles (levatores ani), which are the chief support of tlu^ pelvic viscera, and an arrangement of fascise and muscles, the components of which act as accessories. Until very LESIONS OF THE PELVIC FLOOR. 15,'j rooontly tho porinoum was considoriHl ns n thick wcdjifo- slinpcd body, (K^sigiuiti'd as tlio "poriiical body," wliicli, acting as an inverted koyntone of an arch, 'nati^ialiy aided in the support of the uterus. It is now more accurately regarded as a movefible centre of attachment for the muscles and pelvic fascia; which enti^r into the formation of tlie pelvic floor, as w(dl as for tlu' attachmc^it of the lower portion of the rectum and vagina. By a study of its anatomy and the resiilt produced by the more or less complete laceration of it, its functions can be more readily estimated. Briefly, it may be said to assist in sustaining the anti^rior wall of the rectum, preventing a prolapse of this canal, which, should it occur, would havi^ a tendency to drag down the upper vaginal concavity and destroy the equilibrium of the uterus. In the same way it assists in sustaining the posterior vaginal wall which otherwise would allow of a rectocele. The anterior vaginal wall, and with it the bladder, is in part supported by the posterior vaginal wall, and a sagging of this would tend to the production of a cystocele. If affords by its presence in the act of defecation counter-pressure, by which the focal mass is turned br, "kward to follow the curve of the canal, before it is ejected. The perineum may lose its tonicity or efficiency from the following causes : — 1. CoiistitntioiKil fcchlrncss. In girls of weak deli- cate flbre, the pi^rineum will, without any assignable cause, be found incapable of performing.; its functions. Such cases are not commondy met with, but when they occur, the examining finger reveals not only abnormal relaxation of the perineum, but of the vaginal walls as well. 2. Fcchlcnci^s. flic result of proloiij/cd orcr (listciisioii. When a prolapsed uterus remains for a long time betwinui the labia, the perineum, by over distension, loses its power, and, after restoration of the uterus, remains per- manently enfeebled. This condition is likewise produced 11 154 MEDICAL AND SURGICAL GYNAECOLOGY. by the proHcnco of largo fibrous polypi, or by the wearing of Inrgo globular pessaries. 3. Siihinroliifioii. During utero-gostation the perineum undergoes physiological hypertrophy, which continues until delivery. Involution may fail to take place, and it will thus remain large, lax, and wanting in contractile power. Subinvolution often affects the vagina and perineum simultaneously, and, as a result, the anterior vaginal wall and bladder sag downward for want of support, and the posterior vaginal wall and rectum pro- trude over the ineffectual perineal barrier. •4. Senile atrophi/. Complete uterine jirolapse is by no means rare in old women. As the decadence of advancing years shows itself, the perineum, hitherto strong, becomes inefficient and inactive. 5. Ldcevdtion. Injuries due to the passage! of the child during labor are exceedingly common, and a large proportion of female diseases take their origin thus. Rupture of the perineum furnishes one of the most fruit- ful sources for the absorption of septic elements; and thousands of women suffer throughout their lives from uterine displacements, (nigorg(Mnents. an<l vesical and rectal prolapse, from injuries intiicted upon it during parturition. Presented thus to the intelligent obstetrician who has familiarized himself with the anatomy and physiology of the perineum, it is difficult to understand how there can be any doubt of the propriety of early closure of a rup- tured perineum, for should the operation prove a success, the gain to the patient will be great; if it prove a failure, no evil will have been done. From what has been said it will be readily understood that certain diseases, disordturs, or conditions are apt to bo associated with, or to be the direct outcome of lesions of the pelvic tloor. They may bo thus enumerated:— LESIONS OF THE PELVIC FLOOR. 155 1. Prolapse of the vagina. When the tono of the wall of the vagina 1ms boon impaired and it ijonches into its own canal, so as to fall downward toward the vulva, the condition is called prolapsus. From a study of the anatomical relations, it will be readily seen that prolapse of the vagina, without simultaneous displacement of one or more of its surrounding viscera, must be considered as exceedingly rare, and that it must of necessity be asso- ciated, to some extent, with rectocele, cystocele, or uterine prolapse. Among the causes of prolajjse may be men- tioned violent efforts of the abdominal muscles, repeated parturition, senile atrophy, rupture of the perineum, previous distension by tu- mors, and subinvolution of the vagina and perineum. The displacements may be of two forms, acute, or that form which comes on as a r<'s-':ll of violent effort, which, with great sudden- ness, forces the contents of the abdomen down upon the pelvic viscera, and is generally accompanied by sudden descent of the uter- us. The ordinary or chronic form is that which, by slow and steady action of one or more of the causes enumerated, little by little forces the folds of the vagina downward, toward or through the vulva. 2. Ci/storele, or prolapse of the bladder, consists of descent of the bladder toward the vulva, so as to impinge upon the vaginal wall. When the anterior wall of the vagina ceases to afford the required support, tlu^ bladder ^^^iiff Fig. 41. — Cystocele and Rectocele. ir)() MEDICAL AND SURCJICAL GYNECOLOGY. descends and forms n siiihII poucli in the vagina, wliitth gradually increases until it forms a de(!ided tumor and protrudes between the labia. Residual urine retained in this sjjecies of diverticulum decomposes, cystitis nud vesical catarrh are established, all of which further annoy the patient by the new set of symptoms pnxhiced. 3. Rccforcic, or prolapse of the rectum, occurs in a similar manner, and the pouch thus formed soon becomes filled with fecal matter. The feces becoming hard, and in consecpience irritating, create mucous inflammation and discharge, accompanied by tenesmus, obstinate constipa- tion, and hemorrhoids. 4. Eiifcrocc'lc, or prolapse of the intestine, consists in descent of a portion of the small intestine into the pelvis, so as to encroach upon the vaginal canal. Loops of intestine, finding their way to the bottom of Douglas' pouch, gradually stretch this serous prolongation and, advancing between the rectum and vagina, push the posterior wall of the latter before it so as to form a tumor at the vulva. Treatment. Should the accident have occurred sud- deidy, reduction should at once be accomplished, and the recurrence of displacement prevented by appropriate means. Sudtlen cases of vaginal prolapse, cystocele or rectocele are, however, very rarely met with, and it is mostly those which have slowly and gradually established themselves that demand treatment. The methods adopted for overcoming such cases are: — 1. By the use of loral astriiigeiit^i and by the persistent insertion of minlicated astringent tampons. These methods will often restore the tone of the vaginal walls and bring about a complete cure, but they can only be effectual in slight cases; in those of graver character they will prove iusuflicient. 2. By st(pf)lewentai'j) unpports. Numberless forms of special supports have been invented for the purpose of LESIONS OF THE PELVIC FLOOR. 157 ntfording relief, witli more or less success. The vaginal pessary does little or no good here. In many cases no pessary which rests upon the walls of the vagina can be retained within the distended canal; in others none can be found capable of resisting the downward pressure; while in all, increase of dilatation and atony is affected by them. In some cases an exception will be found to this rule in Cuttc^r's cup jjessary, or some similar instru- ment, supiiorted by an external attachment. Gehrung's pessary, while it does not cure cystocele, gives much comfort to the jsatient, and may obviat(^ the necessity for oi)eration, when such is considered inadvisable. ii. By sHiujIcdl procedures. Of these there are three, any one of which may prove effectual. If a ruptured p(^rineum seems to produce the want of support, peri- neorrhaphy may be all that will be necessary. Should this not be sufficient, colporrhaphy should be performed on the anterior or posterior vaginal wall, as one or the other seems most at fault, and should tlu^ condition be still furtlua* aggravated, an anterior colporrhaphy and posterior colpo-pi^inciorrhaphy may be resorted to, to retain the prolapsed structures. Colporrhaphy or elytrorrhaphy is an operation re- sorted to with the idea of constricting the vagina so as to diminish its calibre and, by this means, remove the traction exerted by its fall upon the rectum, blackler and uterus. Anterior colporrhaphy. Hims' iii, "khL The patient is placed in the dorsal position, and the knees sei)arated by a Clover's crutch. A vulsellum is inserteid into the anterior lip of the cervix; a tenaculum hooked into the mucous membran(> of the anterior wall of the vagina, just below the urc^thra, and a Sims' large speculum introduced. Two tenacula an- next hooked in near the lateral sulci, and the amount of tissue to be removed is estimated by approximating them. By making a snip 158 MEDICAL AND SURGICAL GYNiECOLOGY. with n pair of scissors on encli side, the grontost width of tlio surfnco to bo denuded inny be thus marked out. The whf)ie surface to be pared is put on the stretch and, with a pair of scissors curved on the flat, a strip of mucous membrane, about one-third of an inch wide, is raised in the form of the letter "V," the apex being just below the ur(>thrn. the arms passing up on each side so as to includi^ within them the amount of redundant tissue. Fit;. 42. — Clover's Crutch. Tlie two extremities of the arms pass back laterally as far as the cervix, and by a removal of additional strips of mucous membrane at right angles to the extremities of the arms, they are made to approximate each other in front of the cervix. Commencing at the apex of the triangle, catgut or silkworm sutures are passed beneath the denuded surface on one side, and then crossed over and passed beneath the denuded surface on the other side. After insertion the lateral denuded surfaces are approxi- mated and the ligatures tied, care being taken in this, as well as in all similar operations, not to draw the sutures too tight lest they cut their way out. Hrujar makes his denuded surface in the form of a lozenge or rough ellipse, with the long diameter in the long axis of the vagina, and advises the excision of all the redundant anterior wall. Closure of the wound may be LESIONS OF THE PELVIC FLOOR. 15<) carried out by through niid through sutiiros of silkworm passed beneath the denuded surfaces, or by means of deep and superficial layers of iuterruptt^d sutures, or by two or more layers of superimposed continuous sutures. Stoltz''s iiif'f/tod consists in making a circular denuda- tion, embracing the larger portion of the prolapsed vaginal wall, and then passing a thick silk suture, witli a needle at either end, just outside the edge of the wound, begin- ning at the point nearest the cervix and emerging on either side just below the meatus. The stitches are not entirely buried, but are made to emerge and enter again at short intervals, and when the denuded portion has been pushed up they are crossed and carefully tied. Lcfo rPs opcrntion consists in dcniuding an elongated quadrangular surface on the anterior and ijosterior surfaces of the prolajjsed vaginal walls, and then uniting them by sutures, replac- ing the uterus as the sutures are tied. It is obvious that this oper- ation can only be select- ed for patients of ad- vanced age, or for those who have ceased to men- struate. Posterior colporrha- phy consists in the de- nudation of an elliptical surface on the posterior wall, similar to that described, but it is seldom resorted to alone, When indicated, it is generally combined with perineorrhaphy, forming the operation known as colpo- perineorrhaphy. Fic. 43. — Stoltz's operation for cystocle and Hegar's operation for rectocele. Kit) MEDICAL AND SURGICAL OYN^COLOCiY. PERINEORRHAPHY. By this term is monnt rostorntioii of tho porinoum. Tliis oporntivo procodurc is not limited to tlu> euro of Incoratioii tho rosult of parturition, but is npproprinto to tho restorntiou of n porinoum which has k)st its power and functions from any of tho causes previously men- tioned, and when porformt^l for such is to be conducted upon exactly the same principles as those which apply to the operation for laceration, Varieties of laceration. In its simplest form tho ln(H^ration extends through the mucous mombraiio of the vagina, the integument, and tho junction of the bulbo- cavernosus with the transversus perinei muscles, as well as through a few fibres of the levator ani and correspond- ing fascia?. It may be more extensive, and prolonged I backwards, so as to involve tho structures as far as tlie sphincter. Those forms have boon designated as hicom- })l('f<' rupture. Tho rupture may extend througli the sphincter ani, to which the i -.mo complete 7'upt\irc has been given; or it may extend still farther and involve more or less the recto-vaginal septum. Instead of any of tlu>so, the laceration may be a subcutaneous separation of i\\v, muscles of tho pelvic floor, at, or near their junction in tho median lino. The evils resulting from partial rupture are by no means insignificant, but they are more tolerable than those which follow complete rupture. When the sphincter ani is torn through, and still more markedly when the rectal wall is ruptured, incontinence of feces and rectal gasc^s occur to such an extent as to embitter the life of tho patient. The consequences of rupture of the perineum may thus be presented: Subinvolution of the vagina, prolapsus vaginio with cystocele or rectocele, prolapsus uteri, incon- tinence of feces and prolapsus recti. It is the oi^inion of many that a laceration which does sever the sphincter may unite witiiout surgical treatment, but it is doubtful LESIONS OF THE PELVIC FLOOR. 1<)1 if comploto rostorntion ever occurs by iinmcdinto union. Repair is occnsionnlly effected by grnnulation, and often is very efficient, but never perfect, on account of th(^ tendency to formation of unnatural adhesions, cicatricial bands, and cicatricial tissues, with the consequent con- tractions, retractions, d'stortions and indurations. Operation for incomplete rupture. The patient is placed on the operating table in the dorsal position, the legs being held apart by Clover's crutch. The first part of the operation consists in denuding the surfaces to be united, the extent to which this should be carried on de- pending upon the extent of injury, and tlu^ amount of pro- lajjse of the vaginal wall. A point is marked on each side as high as the denudation should extend, the seat of the highest caruncu- la myrtiformis often serving as a good guide. Grasping the tissue at one point with a pair of tissue forceps, scissors are made to remove a strip, at the junction of the skin and mucous membrane, from this point to a corresponding one on the op- l)osito side. In a similar manner a strip higher up is removed, and so on until a sufficient surface has been Fi<;. 44. — Operation for Incomplete laceration of the perineum. Denntlation completed, and sutures in the recto-vaginal septum introduced. 162 MEDICAL AND SUIUilCAL tlYN/ECOLCKlY. (ItMiudi'd. The (liHtnnco to which tliiH should b(^ oarric^l up will dopiMid upon tho oxteiit mid ttluiractcr of thu injury. If thero is no prolapso of th(^ pelvic floor, or of the posterior vnginnl wall, it will suffice to denude the surface as far as the original laceration only, otherwise it may be necessary to carry the denudation high up on the vaginal wall. H('morrli(i(/(' can generally be controlled by si)onges and hot water. If there is any decided spurting it may be checked by a light pinch with hemoBtatic forceps, or by the temporary introduction of a ligature until the I jiiLlMBiili'L " °°W 11- sutures are intro- r M?m^-. ir M / duced and tied, when all hemorrhage will then be brought under control. Com- mencing in the up- per angles of the denuded surface which point toward, or lie in the lateral sulci, sutures are in- serted on each side. After these have been placed, a silkworm suture, threaded on a good sized, full-curved needle, is inserted through the skin, at the poinl where denudation was first started, and passed outward deep into the tissues. It is then curved round in the tissues in front of the rectum, then deep into the tissues on the other side, and made to emerge at a point corresponding to the one where it was entered. If there is any difficulty in making the needle follow this extensive curve, it may be brought out in the median line Fig. 45.— Operation for lacer.ition of the perineum and sphincter ani. Denudation complete. LESIONS OF THE PELVIC FLOOR. 163 nnd ro-iiiftortod. Tho noxt suturo is inserted in tho snmo way, about tlircc-ci^litlis of an inc^li ncunT the anus, and so on with tho third and fourtli, until thi^ posti^rior anglo of tho wound has boon roachod. Tho catgut suti'-os first introducod within tho vagina aro now tied and cut short. Noxt in ordor, tho first silkworm sutun* is brought up, and, when tiod, unitos tlio highest points of tho lateral odgos of tho denuded surface, and now forms tho now posterior c jmmissure. Tho remaining sutures aro next tied in ordor, and the wound drossod with borated iodoform powder and with strips of iodoform gauze laid over tho vaginal and perineal sutures, after which a pad and " T " bandage aro applied. It will probably bo necessary to cathotorizo the patient every six hours for a d"y or two, after that slu> usually can pass tho urine voluntarily. On tho second evening a mild laxative may bo given and a soap and water enema the next morning, after which the bowels should be moved daily with an enema. Tho external sutures may be removed on the ninth day and tho patient allowed up at the end of two weeks. Operation for complete laceration. The two varieties, laceration of the sxjhincter ani alone, and tliat involving the recto-vaginal septum as well, may conveniently bo considered together. If the bowel be not injured above an inch and a half from the sphincter, one operation will suffice, but if it extends far up, it is better to close it by a primary operation, consisting of vivifying its edges and uniting them. When tho sijhincter ani has been ruptured, the severed ends are drawn outward and backward by the retraction of the muscles, until they lie on either side nearly on a line with tho posterior walls of the rectum, and are often easily recognised by a pitting or depression at these points. Tho process of denudation should bo begun by seizing the end of the musck^ on one side, and with scissors exciso a strip of tissue, so as to free the torn 164 MEDK'AL AND SUR(HOAL (lYN-ECOLOOY. cud of tlu' muHcl(>. From tlioro it in to bo cnrriod forwnrd and inward across the brid^'c formed by tlie recto-vaginal Hcptum, cutting away all cicatric^ial tissue fouiul in it, after which the denudation is to be continued down the opposite side, so as to expose the torn end of the sphinct(^r there. After this, the denudation is carried upward upon each side to the poiiit where the laceration be- ^an, or even higher, if there is much relaxation of the rectal and vaginal walls. At this stage of the vivifying there are two broad denuded sur- faces, one on each sid(\ connected by an isthmus formed by the rt^cto-vag- inal septum. When the recto- vaghial wall has been iir. olved for a short distanct^ catgut sutures ar(^ to be insi'rted from the rectal side, tlu^ lugh- est one first, and, by F'r<;. 46.— Complete laceration iif perineum extend- <■ i c ing into recto vagin.\l septum. Denudation meailS ot them, Carcrully complete, and recto-vaginal sutures inserted. , . coaptate their denuded surfaces. Care must in every case be taken to properly unite the denuded ends of the sphincter. For this purpose a silkworm suture or braided silk is to be inserted a quarter of an inch behind and inside the end of the retracted muscle, and carried under the denuded surfaces parallel to the repaired rent in the septum, so as to unite the innermost fibres. A second suture is inserted at tlu^ outer end of the broken sphincter and carried around parallel to the first, after which both are tied. A silkworm suture is next entered at the highest lateral point of the LESIONS OF THE PELVIC FLOOR. K)") (UMMuliitioii, wlirn^ tlic iM^w rommiHHiirc is to Im^ formed, and carried around after tlu> inaiiiicr dcHtTihcd for iiicom- ^p.rr^ 'P^'t^rf/; % '.>--<i m. Fl<;. 47. — DiaKrnin of operation for simple rupture. Fig. 48.— Operation for complete rupture. ploto laceration, after which the remaiiid(T of the operation is to be tinished in the manner already described. Flap-splitting operation. The operation referred to is tlmt introduced by Lnwson Tait, and recommended after him by Saenger. After the patient has been placed in the lithotomy position, the left index finger of the operator is introduced into the rectum, a blade of a pair of sharp-pointed scissors is inserted in the median line of the perineum, where the cicatricial tissue meets the skin, and is made to cut to the left in a curved line along this margin, to the upper border of the perineal cicatrix. The scissors are again inserted in the median line and made to cut to the right, so that when complete the incision assumes a "U" shape. The upper vaginal tlap is then drawn upward, in front of the vestibule, by means of tissue forceps, and the lower rectal flap downward, by similar 166 MEDICAL AND SURGICAL GYN/ECOLOGY. menus, increasing, if necessary, th's '>ow formed quadri- laternl surface by splitting the septum farther up. A curved needle, pushed through the skin, outside the wound, at the anterior end of one incision, is made to pass under the cut surface, and is so directed that it will pass through, or just in front of the commissure formed by the two flaps and emerge through the skin on the other side at a point corresponding to the point of entrance. A similar suture is inserted half an inch farther back, and made to travere t the tissues of the rectal flap lower down. Vn:. 49.— Flap-spHitiiig operaiicii for in- complete l.icer.-ilion of the Derineiini. Lines of incision. I''n;. 50. - Flap-spliltinj; opei,.iion (ot complete laceration of the perineum. Lines of incision. One or two more are similarly inserted farther back, according to the size of the denuded surface. The first ligature is then tightened, aft?r <-hit the remainder. Instead of passing the sutujes through the skin, Tait recommends their being passed ju.-st within the edge of the wound. The almost inevitable puckering of the vagintd flap is corrected, by short interrupted catgut sutures passed froi- one mucous surface to the other, through its w'ole w.'dth. LE.IIONS OF THE PELVIC FLOOR. 167 In complete laceration, tlio scissors are made to enter the n '^o-vaginal septum forming the isthmus and, after splitting it and making the anterior incisions, the scissors are re-entered, and an outward and backward incision is made on each side, so as to reach and denude the retracted ends of the sphincter ani. The rent in the septum, if any, together with the margins of the spliincter, are ai)proxi- mated in tlie same manner as already described, after which the sutures are introduced precisely as in the incomplete form. COLPO-PERINEORRHAPHY. Hegar's operation. Incomplete rupture. As the name implies, there are two parts to the operation, that which narrows the vagina, and that which api)roximates the muscular fibres. Th former is entirely intra- ^^^^U•j:^?x^-i' vaginal, the latter partly vaginal and partly perineal. On each side, at points, h, c, (Fig. 52), corresponding to the original commissure, ^lie mucous membrane is caught up and nicked. High up on the posterior vaginal wall, above the rec- tocele curve, a, a similar mark is n\ade and the three points united by lateral linear incisions. Tiie apex of the tr'-^ngle is seized, and the flap dissected down to the base of the triangle, he, which forms the margin of the laceration, and there cut oflF. Dee « buried catgut sutures, alterna' ing with super- ficial ones, 1, 2, 3, 4, 5, 6, 7, 8, 9, passing through tl^e ;. 5''.— Flnp-spliieinp o|)eration foi l.icer.-iled perineum — Appearance of wound and in- trtxUictioii of sutures. 168 MEDICAL AND SURGICAL (lYN.ECOLOGY. tlie niargitiK of the domulwl surface, are iiisertt^d from above downward, whieli, wlieu tied, uuitt^, f<(. A silkworm suture is carried up under tlie wound, from a point a short distance from the median line, //, to a point near the closed lino, /, and down to the corresponding point on the other side. The second suture is inserted midway between the first and tlu^ point, c, brought out on the edge of the denuded surface at, h, reinserted on the other side at, /, and brought out through the skin at a point correspond- ing to its entrance. The last suture is inserted near, c, brought out at, k, rein- serted at, ,/, and brought out through the skin near, /). After being tied, a few su- perficial sutures may be in- serted to ensure coaptation. Complete laceration. A point is taken n* r, in the median line, an inch ril:ove. Fig. ,s2.— Heg.ir's Colpo-p.-rineorrhaphy : sii- f, (Fig. 53 \ the UJ>per pjillt Hires s, 7, and g slant tlownwaril toward the . ' , . ' entrance, and are hronglit mil about a quar- in tllC Tent lU tho VCCtO- terofan inch from the median line ; />', the , _ 1 1 rn triangle shown in .( having heen closed, the vaginal Wall. 1 WO otlierS, perineal sutures are inserted — lo, alllniried; i i i i i i II .anc 12, partly free-all in a slanting O, aild, O, locatcd at tlie loWCr end of the labia, at points where we desire the new commissure to be, are next marked out. Commencing at, .r, a curved incision is mad(> along the line, xnh, and then curved downward, along the line, hdy to, (/, tho point indicating tho torn end of the sphincter. LESIONS OF THE PELVIC FLOOR. IC/.) KlG. 53. — Hegar's operation for complete laceration of the perineum. A similar incision is next mnde on tlu' otlu^r side ; the points, (/, and, c, are carefully denuded and made to communicate with each other by carrying the ilenudation across the recto-vaginal septum, removing nil cicatricial tissue there. The surface thus mapped out is finally denuded. Sutures are inserted from side to side, under the whole raw surface represented by, .rmu. Next the sutures in the recto-vaginal wall, if any are required, are inserted, followed by those for coaptating the sphinctei', after the manner already de- scribed. Next the lines, ma, and, nh, are brought together by deep catgut suturo^s, reaching half way under the raw surface, and fairtlier coaptated by superficial ones. Finally four or five silkworm sutures are placed rather superficially on the perineal surface. Emmet's operation. The top of the rectocelo, li, is caught up with n tenaculum, and other tenacula are inserted at the highest caruncula myrtiformis on each side, T, Tl, (Fig. 54), while a fourth is inserted at the median line, H, in front of tlie anus. By drawing in divergent directions on all four tenacula at the same time, a rhomboidal part of the mucous membrane of the vagina is put moderately on the stretch, with two triangu- lar-like Hurfaces, apex upward, extending outward and upward in the lateral sulci of the vagina. The mucous membrane is now removed from the "M" shapi'd space, particular care being taken to go deep enough into th(> sulci. The insertion of the sutures is begun at the upp(>r angle of one side, passing them from the outside towards 170 MEDICAL AND SURGICAL GYNiECOLOGY, the nicdinn lino, not strniglit norosH, but first downwards and inwards to the centre of tlio donndcd surface, and tlien upwards and outwards through tlK> tongue of tlu^ ct^ntral dap. A series of four or five of these sutures are passed and at once tied. Having completed one triangle, and the other treated in the same way. a roughly quadri- lateral raw surface will still De found to be left. A full- curved needle, threaded with silkworm, or silk, is entered through the skin, at the upper and outer angle of the wound, near the point, T, and made to enter laterally Kl(i. 54. — Kmniet's colpo-periiieorrhaphy. Deniul.ilion complete, anil sutures inserted in left triangle. Kui. 55.- -Sutures in both lateral tri.ingles tied, leaving quadrilateral denuded surface with sutures inserted. deep into the tissues, after which it is curved up under the raw surface to the tongue of the flap, under the tip of which it is passed. The needle is next made to traverse a similar course and emerge through the skin at a point, Tt. on the o])posite side. This is sometimes called the "crown stitcli.'" Half an inch nearer the anus another suture is inserted, and made to travel under the denuded DISEASES OF THE VAGINA. 171 surfnco lower down, after which n third nnd fourth, if necessary, are placed in the same order. Tlu' tirst suture is then drawn up and tied, the effect of which is to bring, T, T 1, R, together and form a new commissure by reuniting the upper angles of the original lacerated sur- faces, and interposing between them the crest of the rectocele. The remaining sutures are tied in order, and, if necessary, a few coaptation sutures inserted. Emmet's operation for complete laceration is somewhat similar to the method described as Hegar's, and thus a separate description is scarcely recpiired. CHAPTER XVI. DISEASES OF THE VAGINA. MALFORMATIONS OF THE HYMEN. The hymen is a small crescentic membrane which separates the vulvar cleft from the vaginal canal, and may be considered as the portal to the vagina. There are many conformations of the hymeneal membrane all of which may be perfectly normal and physiological (Fig. 8). Absence of the hymen. The hymen may be entirely wanting, or only a trace of it may be present, even though the genital organs are perfectly normal, but such a con- dition is exceedingly rare. Atresia hymenalis, or imperforate hymen is a malformation in which the hymen forms an imperforate diaphragm. Tliis condition prevents mucous, cast-off epithelial cells and menstrual blood from passing away by the natural channel, and permits of its accumulation above it. In childhood no bad effects will be notice^', except in rare instances arising from accumuhition of mucous. After puberty, the constant repetition of the nu-nstrual period causes an .iccumulatiou of blood in the vagina {luvmnto- colpos), which, by reason of absorption of the serum, 172 MEDICAL AND SURGICAL (JYN.ECOLOGY. sliriuknge of the corpuscles, niul ndmixture of the mucous, bc'coincK converted into a thick, dark browu, tarry mass. Tlie j^'irl pcwsi'ssed of sucli an abnormality has the symptoms of nu^nstruation evi^ry montii, but no blood is scon. The increase of menstrual blood cnust^s pnin, which becomes aggravated each month, and with it occurs the formation of a tumor gradually growing in size from below, upward. If the symptoms of menstruation have persisted for several months, probably enough blood will have accumulated to distend fully the vagina, and to cause a bulging of the imperforate hymen. The cervix may next become dilated and distended, the two forming one globular mass, on the top of which may be felt the undilated body of the uterus. The body of the uterus itself may take part in the dilatation {luvnudo- mctra), so that on making a bimanual examination there will be found, lying between the vulva and the hypogastric region, a globular, tense, very slightly fluc- tuating body, corresponding in outline to the distended uterus, a wave of fluctuation being transmitted from the fundus uteri to the i^rotruding surface at the vaginal orifice. The Fallopian tubes may, in their turn, form large tumors, filled with blood {li(T'ni(if<>s(i1j)iii,r), the blood contained in them being not always pressed out from the uterus, but coming sometimes from the mucous membrane of the tubes themselves. A (litujnosis can very easily be made, when the history, symptoms and subjective signs are taken into consideration. The tumor formed may nearly fill the pelvic cavity and, by pressure, produce vesical and ri'ctal symi)toms. It may form n tumor in the perineal region. KlG. 56. -Atresia of the vaginal outlet. DISEASES OF THE VAGINA. 17)5 ns Inrgo ns n fcutnl hoad, which finttons out the frenulum, and is continuous witli the skin on tlie distended periucnini nnd Inbin ot the vulvn, in front of which will be found tiie meatus. The dangers arising from such a condition are self evident. Spontaneous rupture through the hymen is very rare, hence, if left alone, it may lead to rupture of the vagina, uterus, or tubes, and even operative inter- ference is not without its dangers. Trcdtmcni. When tlu^ tumor is small and confined to the vagina, a crucial incision, or one made by cutting along the insertion of the liymen. is to be made, the cavity irrigated with a warm alkaline solution, such as soda bicarbonate, or lic^uor potassje, and subseciuently with a 1 to 2(XX) sublimate solution. To prevcait septic absorp- tion, the cut margins may be touched over with the thermo-cautery, and some strips of iodoform gauze intro- duced to allow for free drainage. When the accumulated mass occupies the uterus, the dangc^rs arising are those of rupture of the tubes and sepsis. To avoid the former, the utmf)st delicacy in manipulation must be observed, and no attempt at rapid evacuation made by pressure on the tumor or otherwise. To avoid the latter a large opening should be matle and the accumulated fluid carefully washed away, the cavity irrigated and free drainage established. If luematosalpinx can be made out before operation, it is best to remove the distended tubciS first, together with the ovaries. The subsecpient treatment will consist in irrigation with antiseptic solutions and in maintaining free drainage until involution has been well established. MALFORMATIONS OF THE VAGINA. Atresia and Stenosis. The term (itva^id signifies an imperforate condition, and in its strict import is limited to complete closure of nil aperture or canal. Any obliteration or occlusion so extreme as to remove the case from the class of strictures, and yet is not complete, is 174 MEDICAL AND SURGICAL OYN/EC!()LOOY. stylod stenosis. Somo authoritioa uso tlu> term iitrcaia to si^tiity both conditions, marking the divisions by the terms complete and incomptete. The vagina, in fojtal lift?, is created from the approxi- mation and amalgamation of the MuUerian ducts ujion the median line, and to arrest of developmcmt of these joarts a great variety of congenital malformations are attributable. There may bo no trace of the vaginal caiml, the ducts of Muller seeming to have failed entirely to develop; there may be a distinct fibrous cord marking the site which it should have occupied, somo slight devoloijment appearing to hav(^ oc- curred; development may exist for some distance up the canal, failure having taken place above; or one duct may have developed in part above and another below, giving two cul-de-sacs, separated from each other by impervious tissue. Not rarely the whole canal is ill developed, and the hymen guarding its outlet a closed unyielding membrane — a con- dition often combined with an infantile uterus. The vagina may be divided by a more or less complete longitudinal partition into two halves, eacli of which corresponds to one Mullerian duct — a condition often combined with double uterus. Double vagina may be combined witli atresia on one or both sides, and if one side is pervious, the condition may be overlooked for a long time. While congenital defective development is one of the frecpiont causes of atresia and stenosis, it may occur as a result of injury from mechani(!al, chemical, or pathological agencies. A vagina once fully developed may close entirely from adhesions of its walls, or its calibre may be diminished by absolute removal of its Fit;. 57- — Extern.al appearance of (loulile vagina. «, /', v.^gillaI orifices. DISEASES OF THE VAGINA. 175 coinpoiuMit Htru(!tuniH in consoquonco of Hloughin^ pro- duced by impaired vitality, by prolonged or difficult labor, by chemical agencies locally applied, or by syphilitic or other extensive ulceration. Hi/nii>f()nii<. T\w condition will demonstrate its ex- istence oidy by incapacitating tlu^ vaginal canal for the p(vrff)rmance of its functions. Should it occur in ont> too old, or too young, to rec^uire such funtitions from the vagina, it may attract no notice. Amenorrluua alone, or combined with those symptoms of retained menstrual blood already describcnl when spi^aking of imperforate hymen, or inability to perform the act of coition, will probably first bring tlu> sufferer under notice. On making a physical examination, the entrance of the finger into, or up the vagina, will b(^ found difficult or impossible. In- vestigation will prove that it is not due to vaginismus, or udhesion of the labia. The introdut^tion of a sound into the bladder, and the finger into the rectum, may discover the canal running up as a fibrous cord, or no tracer of it whatever may be found. DoubU> vagina can generally be very readily made out, but when there is atresia on one side the diagnosis may not be so easy. In this there will be a menstrual discharge from the open side and retention in the other half, ff)rming a luiMuatocolpos or hiumatometra. From UK're occlusion of tlu^ vagina there is no imnu'diate or direct derangemc^nt, but in those cases where ther(> is retention and accumulation of menstrual blooil in the portion of the canal above the stricture, or in the uterus, the danger assumes the same proportions, or even greater than in imperfon.te hymen. Trcatincnt. The possibility of removing tlu^ abnormal state will depend upon the extent and completeness of the obliteration, or upon tlu^ destruction of tissue. General uarrowni^ss, due to arrest of development, may be success- fully treated by the introduction of graduated dilators, anil the treatment kept up until it has reached the normal 176 MEDICAL AND SURGICAL GYNMJOLOGY. size. Whou ntrosin occurs from tho pr(>Hoiic(> of a mem- brnue nbovo tlir hymon {scj)(i(iu rctro-liijinciKflc). it is to bo trimtod on the snmo principles ns for ntresia of the hymeii. If, in complete congenital closure or absence of tho vagina, the uterus be found to be absent also, no attempt should be made to make a vagina, as it is hardly justifiable to expose the patient to the dangers of operation mi^t^ly in the hop(^ of forming an organ of copulation, besides the artificially formed vagina is apt to close again. The situation is entirely different when there is a uterus, with attempts at menstruation or retention of the menstrual flow. Under such circumstances operative interference is imperative. The patient is placed in the dorsal position and the legs elevated by Clover's crutch. A transverse incision is made midway between the urethra and anus. The operator works his way slowly and very carefully up between the bladder and rectum, insinuating his way with fingers and closed blunt scissors, keepiiig at the same time a metal catheter in the bladder. The left forefinger in the rectum will locate the position of the cervix and in- dicate tho direction in which the operator must work to reach it. After reaching tho cul-de-sac and the cervix exposed, tho opening is stretched, accumulations removed if present, observing tho same care as heretofore expressed, and the parts carefully irrigated. A few strips of iodo- form gauze may be introduced into the fornices, after which a hollow glass tube covered with gauze, and jiropor- tionate in size to the new formed vagina, is inserted and held in position by a "T" bandage. Tho tube should be worn for a month at least, during which it should be taken out daily and the parts irrigated. Subsequently tho plug should be worn for an hour each day during a whole year. If absence of tho vagina is combined with absence of tho uterus, but active ovaries present, they should be extir- pated. DISEASES OF THE VAGINA. 177 In floublo vngiiin, If tlio w^ptuni inti'rfi^rcs witli coition, it may bo Hi)lit U^nf^thwise and the marj^ins touclu'd with tlio tliornio-cautory. DoubU^ vagina, with unihitcral or bilateral atresia and retention of the inenHtrual fluid, may bo mistaki^n for luematocele, or a uterine myoma, unless the history of the case is carefully taken into consideration. Unilateral atresia may b(^ treated by introducin?^ a sinnnilum into the open half, and openinj^ into i\\" otlur by means of scissors or thermo-cautery. In double atresia one side may be opened first, as in atresia of the single vagina, and afterwards the septum incised. Faulty communications. As a result of arn-st of development other conditions are sonii'times met with. There may be complete atresia, or absence of any opening on the cutaneous surface leading into the intestinal or uro-genital canal, while under the skin is found a common cloaca, into which open the bladder, vagina and rectum. In other cases the vagina and urethra apparently open into the rectum, being cases of persistent cloaca. The partition between the rectum and the uro-geiutal sinus may have been formed, but tlu^ urethra seems to opt'n into the vagiim -a condition die to persistent uro-genital sinus. VAGINITIS. Vaginitis is the word commonly used to (h^signate inflammation of the vagina, but some autliors, however, have substituted the word colpitis or cli/trifis. Under this term is comprised so many different con- ditions that it is necessary to admit certain divisions and subdivisions of the subject. Thus the intensity of the symptoms and the length of timi^ which the disease lasts, classifies it as (irufc or chronic. It is called prinnrrif when it appears first in the vagina; accotuUtrji when the inflammation invades the organ from another part. Taking the chief features of the disease into consider- ation, vagiiiitia may be classified as simple, yonorrlujcal, ^'*U ^. ^^^„o. IMAGE EVALUATION TEST TARGET (MT-3) 1.0 I.I 11.25 1^ 12.3 |50 "^S M 2.2 lis 20 U illll.6 '^1 '/ Photographic Sciences Corporation 23 WEST MAIN STREET WEBSTER, N.Y. 14580 (716) 872-4503 >GN^ \ ;V :\ \ ^ -f'-^ ^ #. ^^' <* 178 MEDICAL AND SURGICAL GYNAECOLOGY. and (jranular, and to this clnssificntion may be added the (iplithous. cfjsfic, adhcsivo, vesicular, and onphysonah.ns, as forming less important varieties. ^tiolofjy. Any intluence which injures the vaginal epithelium, such as long continued friction from foreign bodies, or chemically irritating secretions or injecta, diminishes the resisting power of the vfiginal mucous membrane. If accompanied by lack of drainage, and t \ consequent accumulation of secretions, bacteria multipl;y, infection follows, and vaginitis results. Among the prcdisjiosinji causes may be mentioned anaemia; chlorosis; constipation; any of those causes which tend to produce unhealthy conditions of the skin; pregnancy; abdominal tumors, or other conditions which tend to produce pelvic congestion. Masturbation; pin worms; pessaries; tam- pons; chemical irritants; retained secretions; pathological secretions from the uterus, urethra, or vulva, or infection introduced from without, such as gonorrhoeal pus, may be enumerated among the exciting causes. The exanthemata are held accountable for a small share of the cases. PathoUnjij. In the acute stage of simple vaginitis, hyperffimia and enlargement of the papilliB take place, with small celled infiltration of the epithelial structure. The epithelium on the summits of the papillfc is shed, but between them it is thickened. The discharge in .some cases is thin and slightly acid; in others it is alkaline and thick; in others purulent. In the chronic form the deeper layers of the membrane become infiltrated, with loss of epithelium in some places, giving rise to ulceration. When caused by chemical irritants, such as strong solu- tions of iodine, a sort of vesication may oc^ur, with exfoliation of large layers of epithelial tissue having the appearance of a false membraiu>. In the gonorrhoml variety the changes are similar to those mentioi'^d, but more pronounced. The papilhe are larger and more vascular, the vestibule and inner surfaces of the labia DISEASES OF THE VAGINA. 179 participnto in those clmugos, while the discharge from tlie first is muco-puruhMit. Later the discharge becomes thinner and more distinctly purulent, and may give rise to infection of the urethra, vulva, and vulvo-vaginal glands. Graanlar vaginilis differs chiefly by the more jjro- nounced enlargement of the papilhe and by more extensive exfoliation of the epithelium covering tliem, causing the surface to resemble a mass of granulations. Adhesive V(i<)iiiitis is a disease of childnni and old people. In them the prtpillffi are smaller and the epithelial layer thinner. The inflammation is usually found more in patches, the secretion scanty, the surface smoother, and often ecchymotic ia spots. The opposed surfaces tend to agglutinate, and by this means the lumen of the fornices, or even of the whole vagina may become obliterated. Cystic or follicfdnr raf/iuitis consists of an inflamma- tion in the follicles occasionally situated about the vaginal fornices, causing the retention of their contents and the formation of small cysts. Aplitliovs viujinHis arises from a development of the oidiurn albicans on the congested or more or less eroded vaginal surfaces, giving rise to whitish patches. Vesicular raijinitis gives rise to round vesicles situattnl on inflamed areas, which, after bursting, leave sharply defined raw surfaces about the size of split peas. Emphjisemaions va(jinitis is an inflammation of the vagina characterized by the development of fluid and gas in the small spaces and canals of the connective tissue and lymphatics at the upper end of the vagina. They project like little bladders on a raised hyperannic base, produce a crackling sensation when felt, and collapse when punc- tured. Pregnancy favors the development of this form. Sympfonis. Acute vaginitis is indicated first by a dull pain in the pelvic region, and a sensation of heat and ful- ness in the vagina, accompanied by a slight rise of tern- 180 MEDICAL AND SURGICAL ftYN^COLOGY. perature and a feeling of malaise. There is a discharge which is at first scanty, but rapidly increases in amount, and often possesses a disagreeable odor. Micturition and defecation become painful, conditions which may soon be followed by severe urethral and vesical symptoms, such as frequent urination accompanied by burning pain and vesical tenesmus. Urethral and vesical symptoms indicate with fair certainty thnt the causative agency is one of gonorrhoea, particularly if accompanied by pain or tender- ness in the inguinal region. Digital examination shows the vaginal orifice to be sensitive, the canal hot and swollen, and at a later period roughened. If the urethra be involved, it will be found thickened and tender, and pressure along its course may cause a drop of pus to exude from the meatus. Pus from this quarter is said to be con- clusive evidence of gonorrhoea also, as gonococci thrive best upon its mucous membrane. If the bladder becomes infected, pressure on the vaginal wall will reveal the fact by the marked increase in the pain produced. Inspection will show the vulva acutely inflamed and covered with a muco-purulent or purulent discharge. The symptoms of chronic vaginitis are similar, but less pronounced. In some cases symptoms of importance are absent altogether, and nothing, except a leucorrlux3al discharge, calls the patient's attention to her condition. It may follow the acute stage, but more often is, from the first, a subacute or chronic process, such, ivT instance, as that form which develops in consequence of discharges from the direction of the uterus, or as the result of senile changes. The more acrid and abundant the discharges become, the more likely will they produce vulvitis and pruritus. Touch and sight reveal the rouglunied surfaces and, if of the gonorrluwal form, vegetations are not uncommon. With the symptoms described, a vaginitis should not be confounded with any other lesion, but it is not always easy to distinguish one form of vaginitis from DISEASES OP THE VAGINA. 181 auotluT. The presence of the gonococcuH may establish the presence of one form, but its absence is not adecpiate proof of the absence of such infection. Corroborative evidence in its favor is found, however, in other directions, the prominent points of which have already been related when speakinj^ of vulvitis. Treafnicnf. Simple acute vaginitis is readily controlled and cured by keeping the patient at rest, by freeing the bowels with mild cathartics, and by the copious use of douches, consisting of a strong aqueous solution of boric acid, borax, or of bicarbonate of soda, at a temperature of 105° to 110° F., every four hours, the vagina being stretched by means of a wire speculum to permit of its application to every part. If the tenderness is so groat as to exclude the use of such an instrument, a soft cutheter may be used, aided by hot alkaline fomentations applied to the external genitals. If there is a suspicion that it is of a gonorrhaml type, or in cases in which the simple form does not readily yield, the fluid used for douching should contain instead of alkalies, bichloride of mercury 1 to 5(XX). If the disease shows a tendency to become chronic, more energetic local measures become necessary. Through a Sims' speculum, the vaginal walls are to be carefully cleansed with green soap and warm water, then wiped over thoroughly with a solution ol bichloride 1 to 1000, followed by another washing of warm water. After cari'fully drying with absorbent cotton, the vagina is to be lightly packed with plain or borated absorbent cotton, or the surfaces kept apart by tht introduction of three or four thicknesses of gauze. This treatment should be repeated daily, until the disease is conquered. In the chronic form, the same careful cleansing is to be carried out but, instead of the bichloride, the entire surface is to be painted with a Hve per cent, solution of nitrate of silver, after which gauze is to be inserted as before and allowed to remain for twenty four hours. This treatment 182 MEDICAL AND SURGICAL, GYN/ECOLOGY. should bo given every three or four days, and in the intervals warm borax douches niglit and morning. Treat- ment by dry powder, such as ecpial parts of bismuth and chalk, or tannin and chalk, and kept in places by a cotton tampon, often proves serviceable when there is a tendency for the discharge to linger. The powder and tampon should be removed every day, the old powder being douched out just before the treatment is repented. Sup- positories of tannni, oxide of zinc, or acetate of lead may be similarly used, with equally good results. In the senile and vesicular forms, mild antiseptic douches are indicated, supplemented by strips of lint smeared with a two per cent, carbolized oxide of zinc ointment and introduced within the vagina. Neoplasms. Cysts are rather frequently found in the vagina of adults or, as congenital formations, in new born children. They are usually single, globular or oblong, and for the most part sessile, but may become pedunculated. They vary in size from that of a pea to a goose egg, but may, exceptionally, reach the size of a foetal head at full term. The contents may bo serous, yellowish, purulent, or thick and chocolate colored. Those cysts may have different origins. They may be formed by con- densation of the peri-vaginal connective tissue around an extravasation of blood, or they may be simple retention cysts. Remains of an ununited du3t of MuUer or of the canals of Grartner may give rise to them. If small they may not give rise to any symptoms, but are discovered accidentally during delivery, or an examination. They may be diagnosed from a cystocole or rectocelo by the introduction of a catheter into the bladder, or the tinger into the rectum. The treatment consists in making an incision over the tumor and enucleating the entire cyst wall, if possible. When unable to do this, removal of as much of the cyst DISEASES OF THE VAGINA. 183 wall as possible is to bo accomplisluMl and the remainder caiiteri7A>(l and packed with iodoform j^aiize. Fi'hronid ((ltd Jiln'(,mi/())ii<i arv rare. Their most com- mon Hcni is in the upper jiart of the anterior vaginal wall. Orifjcinally they are globular, sessile tumors, but when their weight increases they have a tendency to become pedunculated, and may even protrude through the vulva. When they are small they are easily diagnosed by their elastic hardness, but when large they may be mistaken for a uterine pedunculated fibroid. If, however, the os can be reached, it will be undilated and no pedicle will bo found passing through it. Treahmmt. If sessile, it may be removed by making an incision over its longest diameter and, after enucleating it, the cavity closed by rows of superficial raid deep catgut sutures. If pedunculated, the pedicle may be secured by ligature and the mass cut away. Mhcoks polypi are very rare. In shape and structure they are similar to the mucous or glandular jjolypi found in the cervical canal. Prinud'i/ cfcrhwdKi is also fl rare disease. As a rule it is secondary, either propagated by continuity from neighboring organs, or appearing as metastatic deposits from carcinoma in remote parts. As a primary affection it occurs in the form of epithelioma and submucous carcinoma. Epithelioma usually begins as a circum- scribed projecting nodule on the posterior wall of the vagina, which soon breaks down on the surface and assumes the form of a raised, ulcerating, cauliflower-like mass, with everted edges. The submucous or diffuse variety commences as a flat area of infiltration, under the normal vaginal membrane, which spreads along and around the vagina, until the latter feels like a narrow opening through a mass of hard unyielding tissue. Ulceration and excavation sooner or later take place, with corres- ponding softening of the parts. The sijmpfums are at 184 MEDICAL AND SURGICAL GYNAECOLOGY. first confined to a thin irritating dischargo, wliich bi^forc^ loufr becomos ott'onsivc, bloody at times, and containinj^ Homo tissue debris. Pain, radiating from the vagina, is soon experienced, and later t!io symptoms are those which characterize infection of the neighboring organs. The treatment consists in extirpating the dis(uised tissues, whenever possible, and thorougldy cauterizing the wound. When it is no longer possible to remove ail the tissue, the surface may be curetted, and a solution of ''orric chloride applied once a week, if it is tolerated that ot*^^en. Astrin- gent and antiseptic douches will help to diminish hemor- rhage, destroy the odor, and prevent septic absorption. CHAPTEB XVII. GENITAL FISTULA. Genital fistulae are abnormal avenues for fecal or urinary discharge, by moans of which some portion of the intestine or urinary tract communicates with the genital tract. Fecal fistulse are formed by a communication bet ween the rectum or the small intestine, and the uterus, vagina, or bladder. Urinary fistulae are formed by the bladder discharging into tho uterus or vagina; by an opening from the urethra into the vagina; or by a ureter emptying into the uterus oi vagina. They have been designated as vesico-vaginal, urethra - vmjinal, vesica - uterine, vesica - utera - vaginal, utera-vag inal, nretero-uterine. and uretera-vesica-vaijinal. Vesico-vaginal fistula is a communication between the bladder and vagina, and is by far the most common form. These tistuhe may originate from protracted labors, in which the bladder has boon compressed between the head of the child and the symphysis pubis sufficiently GENITAL FISTULA. 185 long to produco n locnlizod nocrosis, niul tbo necrotic tissue thus formed, coming nwny after a period of a few days, establishes the fistulous tract. They may also arise from direct injury to the tissues from the use of forceps, or from injury sustained during surgical oj)erations in the neighborhood of the bladder, particularly hysterectomy. Other agencies may create them, such as pessaries, stono in the bladder, or the presence of other foreign bodies. The vaginal walls may be perforated by cancer, or by syphilitic or other ulcers, or by the formation of an abscess in the parietal tissues. Lastly, certain diseases, producing deficiency of nutrition, may cause localized sloughing of the vaginal walls. Sijmptoms. The chief symptom is indicai3d by a more or less constant dribbling of urine from the vagina, accom- panied by a disagreeable ammoniacal odor. By the passage of this irritating excrementitious material through a canal and over tissues not intended by nature to tolerate it, inflammatory action, pruritus, eruptions and excessive irritability are produced, and the vagina sometimes becomes covered with urinary concretions, and the vulva and thighs red and excoriated. If the fistulous orifice be a large one, even a superficial examination by touch will reveal the nature and extent of the lesion, but the opening may be so small, or so hidden behind the projecting cicatrix, that it cannot be discovered. For their detection a Sims' speculum should be employed, with the patient in the genu-pectoral position, injecting at the same time, if necessary, an infusion of India ink, cochineal, madder, indigo, or plain milk. Treatment. A fresh fistula, even if of considerable size, may be much diminished, and sometimes closed altogether, by the use of warm vaginal douches, and by the internal administration of drugs to render the urine normal, such as salol, or benzoic or phosphoric acid, or benzoato of ammonia. When a fistula has been discovered 1H(> MKDUIAL AND STHdlCAL (iYNECOLOOY. soon after parturition, it hIiouKi bi- treated by such nil thods, as it is too early to resort to suture. The once favorite inetliod of treating all varieties of these Hstuhe by cauterization has now, very deservedly, faHeii into disuse under the inHuenee of improved surj^ieal methods. Closure by siitinw <(f the Hcaf of tlw Jhfiiln. This is the most reliable and satisfactory of all methods. The best time for operating is eight or nine weeks after con- finement, at a period when the patient has regained her constitutional vigor, for in no operation in surgery is this more vigorously demanded. The pvcporotorii tt'catnicnt consists in the use of the same nu'asures as have just been mentioned, namely, warm vaginal douches, the adminis- tration of drugs to render the urine unirritating, and the careful removal of incrustations. If cicatricial bands exist they are from time to time to be cut with a knife or scissors, and the vagina stretched by tht> introduction of a Bo7AHnan's dilator. trims' opcrotion. This operation may be divided into three parts; paring the edges of the fistula; passing the sutures; and apjjroxi mating and coaptating the denuded surfaces. The patient is placed in Sims' position and a large broad-bladed speculum introduced into the vagina. The (.'dges of the fistula are caught up witli a tenaculum and, with scissors, the edges pared all round, to the extent of producing a raw edge one-third of an inch wide, and bevelled from the vesical mucous membrane outward to the vagina, care being taken not to imijlicate the former in the incision. Two sorts of sutures should be used in approximating the denuded margins, silkworm for the deep, and fine silk for the superficial stitches. Beginning at the most remote portion, a slightly curved needle is entered half an inch from the edge of the incision and brought out on the denuded surface, just under, but not including the edge of the vesical mucous membrane. After drawing the suture partly through, the needle is GENITAL, nSTUL.E. LS7 iiitroducu^d jigaiii into tlu* raw Hurfnn^ ()i)i)()Hiti'. jiiKt uudor the vosic^nl ituk^ouh iiuMnbraiic, mid n\ndv to ciiuTj^c lialf an inch from the edge of the wound. The otlier .sutun^s, tivo or six to the inch, are iiiiroduced similiarly, and one at, or just beyond each angle of the wound. The sutures are then brought together and tied .snugly, approximating the tissues without strangulation, after wliich the margins may be mor(> carefully coaptated by sup(^rficial sutures. Tho ends of the sutures having been cut ott*, a loose iodoform gauze pack is placed in the vagina. A self- retaining catheter, preferably of soft rubber, may bo introduced, after carefully washing out the bladder. Many surgeons prefer to trust to frequent catheterization for a Fig. 58 — Operation for vesico vagiii.il fistula, denuclalion complete, and sutures in place. few days, believing that the constant presence of the catheter keeps up continued vesical tenesmus and lessens the chances for immediate union. If the vaginal pack bc^comos wet or soiled, it should be removed, otherwise it may be left in place for two days, when it should be taken away, antl the vagina allowed to remain empty. When the operation was first perfected by Sinii, silver wire, introduced by silk carriers, was used ex- 188 MEDICAL AND SURGICAL GYN.ECOLOGY. cluHivoly, but it in found tlint Hilkworm servoH oqunlly an W(^ll. Tivo ofluT <>f)cr<itions Jiro gouorully doHcribcHl for tho closure of vesico-vagiunl tistuhe, namely, Simon's and Bozemau's, but as they dittVr mostly in the matter of technique, and in tho method of procedure, it is not (!onsi(lere(l necessary to describe the various stejjs. There is a y/ff;;-.s7>///////// (>j)('f((fi<)n, known as Blazius' method, and recently rem wed by Lawson Tait and others. No tissue is cut away, but an incision is made parallel to tho vaginal and vesical mucous membrane, on tho white lino of the cicatrix, to the depth of three-eighths of an inch. The vesical and vaginal flaps thus formed are separated and, in the cleft formed, a vircular suture is introduced, which, when drawn up, approximates the raw surfaces all around. Urethro-vaginal. In this variety the wall of the .septum being very thin, the denudation must be extended over the nearest part of the vagina and the edges brought together from side to side over r. metal catheter. If the tension is great, it may be relieved by n. cing an incision on each side parallel to the line of union. Vesico-uterine. From its anatomical relations, fistulous communication can only take place between the bladder and uterus at the cervix, except under rather rare circum- stances. These fistulte are produced in the same manner as vesico-vaginal fistuloe, and form small round holes opening through the anterior lij, of the cervix. It, too, may be diagnosed by injecting milk or colored fluid into the bladder. Sometimes a probe can be brought from the bladder, through the fistula, into the cervical canal. Trenhncnt. This kind of fistula has an unusual tendency to spontaneous healing, and efforts of nature in this direction may be aided by cauterization. If that does not succeed it may be closed by operative i^rocedure. After having split the cervix in the median line, so as to GENITAL FISTULiE. 189 ronch the fistulous trnct, and denuding its surfaces, sutures nro introduced through the uterine and vesical walls, after wliich tlu^ incision in the cervix is closed the same as in tracludorrhaphy. Vesico-utero-vaginal. In this variety the fistulous tract i)asses from the bladder through the anterior lip of the cervix and ends in the vagina. They are subdivided into superficial and deep, according to whether tlu^re is partial or comi^lete sloughing of the anterior cervical lip. In the superficial form, good results may be obtained by simple denudation and suture, but the deep are rarely amenable to treatment by this metnod, and it is generally necessary to bring the posterior lip of the cervix in apposition with the vaginal edge of the fistula, and stitch the two together. The os uteri therefoi-^ will open directly into the bladder. This operation has been termed vesico- hijiitcro-alcisis. Uretero-vaginal. A uretero-vaginal fistula is situated on the anterior wall of the vagina, a little below and outside of the vaginal portion of the uterus, and is formed between the ureter and vagina. The causes are, difficult parturition, perforation of a pelvic abscess, prolonged use of pessaries, and vaginal and abdominal hysterectomy. Difu/nosis. By placing the patient in the dorsal position and exposing the vaginal vault, the fistulous opening may, with a little patience, be found, though it be only the size of a pinhead, or smaller. With a probe or ureteral cathoter, it is usually possible to enter the ureter for some distance and see the urine coming out drop by drop. A catheter or sound passed into the bladder will reveal the absence of the probe there. Milk introduced through the urethra will not escape through the fistula. Cystoscopic examination will positively clear up the diagnosis. With the ureteral catheters introduced no urine will come from the catheter on the affected side, while on the opposite side it will issue drop by drop. Ill l^R) MEDIOAL AND SURGICAL GYNitCOLOGY. Trrdtmrnt. All uretoro-vnginni fistulre should bo operated upon ns soon as circumstnucos will permit, on account of the great liability of the kidney to become infected. Three operations are available, closure of the fistula, implantation of the ureter into the bladder, and nephrectomy. 1. An elliptic incision is made around the fistula, the ureter exposed, and a sound passed into its orifice. After freeing the ureter for about one third of an inch, an opening is made into the bladder, just above the end of the ureter, and, after removing the sound, the free end of the ureter is turned into this opening and ludd there by two or three fine sutures passing through the vesical and ureteral walls, but sufficiently superficial as not to encroach upon the lumen of the ureter. The vaginal incision is then closed carefully. 2. If a vesico- vaginal fistula does not already exist, one is made by the excision of an oval flap around the ureteral oijening. The end of a very fine gum elastic catheter is then passed into the renal end of the ureter, and the other end into the urethra by way of the fistulous opening in the bladder. The geuu-pectoral position is now assumed and the edges of the fistula denuded. A series of fine sutures are passed through the flaps, at right angles to the ureter, and tied. The catheter must remain in position for at least eight days, and the bladder kept empty for a portion of that time by a self retaining catheter or by frequent catheterization. 3. Implantation of the ureter in the bladder. (Uretero- cystostomy). After opeidng the abdomen, the ureter is dissected out low down, and an opening made in the posterior wall of the bladder by cuttmg down on closed forceps introduced through the ureiiira. A flexible catheter is introduced into the ureter and pulled out through thxC urethra. The ureter is then fastened to the wall of the bladder by fine sutures, after which the flaps GENITAL FISTULA, 191 of peritoneum are mnde to cover over aud close off the point of entrance, fine silk sutures being also introduced for that purpose. If there is difficulty in selecting the proper point for oijoning into the bladder, it may be partially filled with boric acid solution, which is at once to be evacuated after the point has been selected. Finally a self-retaining soft rubber catheter is to be inserted through the urethra by the side of the ureteral catheter, after which the abdominal wound is closed. Uretero-uterine fistula. In this variety the urine flows from the oh, as in the vesico-uterine, but the mt^thods adopted to ditt'erentiate between vesico-vaginal and uretero-vaginal and vesico-uterine will be sufficient to make a diagnosis. This form of fistula is exceedingly rare, and if abdominal implantation cannot be performed, relief may be obtained by turning the cervix into the bladder, by artificial closure of the vagina (colpo-cloisis), or by excision of the corresponding kidney (iie])hrectomy). Indirect methods for the relief of urinary fistulae have been devised. They consist in the closure of the genital canal, at a point below the site of the fistula, so that the portion of the vagina above becomes a part of the bladder, menstruation, if present, taking place into this viscus. Three varieties have been devised : — Antero- posterior closure of the vulva (episio-cU^isis) ; complete vulvar closure with the formation of an artificial recto- vaginal fistula; and the obliteration of the vaginal canal transversely (colpo-cleisis). The two former have proved so unsatisfactory that tliey have been jiractically aban- doned. Colpo-clcisifi. In performing colpo-cleisis care should be taken to preserve as much of the depth of the vagina as possible, and theriifore closure should not be made at a lower point than necessary. A ring of mucous membrane is marked out on the vaginal wall, and with a sound in the bladder, the anterior surface is denuded, and with the 192 MEDICAL AND SURGICAL GYNECOLOGY. finger in the rectum, the posterior surface. Sutures are passed by means of two short half-curved stout needles, one at each end, the anterior needle being passed from above downward, under the denuded surface of the vesico- vaginal wall, and the posterior needle similarly, under the denuded surface of the recto-vaginal wall, and, after all are inserted, they are carefully tied. FECAL FISTULA. |j;| Fecal fistulse are abnormal avenues for the escape of the contents of the small or laige intestine, either by the vagina or by the bladder. Implication of the small intestine is comparatively rare, and that of the bladder extremely sp. The fistulous communication may take place between the rectum and vulva, recto-hihuil; between the rectum and the vagina, recto-vagimd; or between the ileum or sigmoid flexure and the vagina, ilco-vaginal, or entero-vaginal. The size of the opening varies. It may bo so small as to be found with difficulty, or large enough to admit a fiiger. It may be situated anywhere between the intestine and vagina, but it is most commonly found either immedi- ately above the sphincter ani or at the fornix. The causes of fecal fistulae are in many respects similar io those determining urinary fistulje, but the most common by far is child-birth. The symptoms are plain. The escape of flatus and, when the bowels are loose, of their fecal matter through the vagina, readily indicates the condition, but when the fistula is very small there may be some difiiculty in locating it. Distension of the rectum with water will often bring the opening into sight. Treatment. Many small fecal fistula? have a decided tendency to close naturally, and this happy result should be facilitated by scrupulous cleanliness, sitz baths, rectal and vaginal injections, laxatives, and by an occasional light cauterization. GENITAL FISTULyE. 193 Rccto-lahial fistula is best treated as a fistula in nno. If the labial opening be near the rectum it may be cut through, the fistulous tract curetted or denuded, and either packed with gauze, leaving it to heal by granulation, or the surfaces brought together with deep sutures, to heal by immediate union. Many operations have been devised for the cure of recto-vaginal fistulse: — 1. Emmefs operation consists in splitting the perineal body up to the fistula, cutting its wall away, and uniting the same as in complete rupture of the perineum. 2. The fiap-splittiiKj mctJiod described for the cure of vesico-vaginal fistula often gives good results when the opening is small. 3. Make a broad denudation on the vaginal side and extending from the sound tissue deep down into the fistula. De<ip and superficial sutures are passed from side to side. 4. Make a vertical incision in the median line, extend- ing half an inch above and below the fistula, and dissect the vaginal from the rectal wall on each side, for a distance of half an inch. Unite the edges of the rectum by a continuous buried catgut suture inserted from the vaginal side, and afterwards the vaginal flaps by silkworm or chromic catgut. Ent<'ro-va(/inal fistula', when the opening is lateral, may be closed by denudation and suture like other fecal fistuljB. In the case of raxjinal anus no attempt at closure must be made until it is ascertained that the lower part of the bowel is pervious. In ilro-vaginal fisfuhv, and in fistulous openings bv>tween the bladder and intestine, the oidy plan of treat- ment is to open the abdomen, find the fistulous tract, sever the adherent intestine if possible, and, by means of Lembert sutures, close the openings in both viscus. 194 MEDICAL AND SURGICAL GYNiECOLOGY, CHAPTER XVIII. DISEASES OF THE URETHRA AND BLADDER. Malformations of the urethra. Tlio urethra may be entirely absent, due chiefly to arrest in development of the vagina at a point where it should form the main portion of the posterior wall of the urethra. The lower and anterior portion of the virethra may be absent (hyi)ospadias). Airesia of the urethra is a comparatively common affection. There are two forms mentioned: one is produced by imperfect development of the vaginal process, or of both the clitoral and vaginal segments, the urethra being open up to the bladder and there closed. The second form occurs when the clitoral and vaginal processes are both defective. In such cases there is no trace of a urethra, except an imperfect vaginal wall, which extends obliquely dowiuvaid and closes the bladder. The symptoms which aris* from malformation of the urethra are incontinence of ur* in the one cla.ss of cases, and retention in the other. vV'hen the urethra is deficient in part, and the bladder perforate, urine constantly escapes. Atresia of the urethra and the consequent retention of urine causes hydrops of the bladder, ureters, and kidneys. Distention of these organs occurs in utcro, and such malformed children are usually born dead, or die soon after birth. The evil effects of this malformation is sometimes naturally obviated by the occurrence of another developmental anomaly — fistula of the urachus and escape of the urine from the umbilicus. In making a diagnosis of these di^formities, reliance cannot be placed on objective symptoms alone, and a physical examination of the parts becomes necessary. The general relative appearance of the external organs must be observed, aidetl by attempts at passing a sound into the bladder and by the intro- DISEASES OF THE URETHRA AND HLADDER. 195 ductioii of the finger into tlu> rectum find, if possible, into the vnginn. Atresia of the urethra can only be cured by operation. When there is entire absence of the urethra with the existence of vesical fissure, or when there is persistence of the sinus-uro-genitalis with partially developed urethra, the production of an artificial oanal has been suggested. Malformations of Kxe bladder follow the general rule, and are thus in most instances due to some defect in the normal process of development. Fissure is the most frequent and prominent anomaly. It consists in partial or complete absence of the anterior vesical wall, and is usually accompanied by malformations of other organs. It may be a simple fissure of the lower part of the bladder, with an opening about three quarters of an inch in breadth. A higher grade is that in which the fissure is near the umbilicus, the lower part of the pelvic cavity and the [)ubic symphysis being closed, and the lower part of thi bladder, urethra, and external genitals normal. The hir,hest grade {crsfrofilii/) is that in which the whole anterior wall of tlu^ bladder seems absent, the inferior abdominal region much shorter than normal, and the umbilicus nearer the base of the pelvis. The abdominal walls are divided, and the resultant fissure is filled up by the bladder wall. The mucous membrane is puffed out and red, and graduallj' merges into the skin of the abdomen. On each side of the lower portion of the everted bladder are situated the orifices of tlu' ureters. As a rule the urethra is absent, and the clitoris is either divided, or there may remain but a trace of it, or it may be entirely absent. Double bladder may be considered as extremely rare. In such cases the double allantois, instead of forming one passage, forms two, with a ureter opening into each. Various explanations have been offered to account for the malformation; some attribute it to defect in the allantois 196 MEDICAL AND SURGIC.T. QYHMCOLr.i. at an early period in embryonic life, some to a failure of the pubic bones to unite; some to atresia of the urethra, followed by over distension, the distended organ pushing aside tirst the recti muscles, later the cartilaginous pubic bones, and finally bursting, Trcdtmcnt. In t}ie severer form no plan offers any relief except a plastic oper^iion, find this is often only palliative. Even under the most favorable circumstances not much more can be done than to diminish the annoy- ance which comes from the flow of urine over the surrounding external surfaces. The operation which has given most satisfaction consists in dissecting a flap from the central part of the abdominal wall, immediately above the fissure, and large enough to close in the bladder completely. After vivifying the edges of the bladder wall, the abdominal flap is turned down and the edges stitched to it. A lateral flap is next taken from each groin, and brought together with their raw surfaces in contact with the raw surfaces of the central flap, and stitched to it. Irritable urethra. A case will occasionally be met with, in which will be found pain and tenderness of the urethra, frequent desire to urinate, and pain in doing so, while a careful examination will fail to find any lesion. It very commoidy follows catarrh of the bladder, or it may be the result of exposure to cold, or of some temporary or accidental irritation of the bladder. It may be very effectually treated by dilating the whole urethral canal with dressing forceps, or some form of dilator, the operation being repeated several times. An application of equal parts of carbolic acid and glycerine to the whole canal will materially aid in effecting a cure, although urination will be painful for several days after. Urethritis. Urethritis is of three varieties, acute, chronic, and gonorrha'Ml. Acute urethritis, though not a very frequent disease, is a very distressing one, and often DISEASES OP THE URETHRA AND BLADDER. 1U7 difficult to relieve. In mnny cases it will be found to depend upon a speoific cause, yet, like vaginitis, it is sometimes uitfioult to mark the difference. Simple urethritis comes on g/adually, and is often preceded by symptoms of uterine or vesical disease, while the gonorrh(Bal variety comes on rather abruptly, and is preceded or attended by acute vaginitis and vulvitis. In both varieties there is painful urination, and a sharp, scalding sensation produced by the urine passing over the tender surface. The desire to urinate is not so frequent, or so urgent, as in cystitis, and in some cases the urine is retained for a long time, dread of pain on the part of the patient causing retention. During or immediately after micturition, in some cases, a few drops of blood escape, which may be recognized by its being exuded separately, and not intimately mixed with the urine, as is usually the case in hemorrhage from other portions of the urinary tract. Examination will show the meatus swollen, red- dened, and the urethral mucous membrane somewhat prolajjsed. The urethra is felt as a firm, tender cord, and, by pressure from above downward, a purulent fluid can be pressed from the meatus, in which, if the gonocoecus is found, reveals the nature of the urethritis. Cystitis, a disease apt to be confounded with urethritis, may be differentiated by using the catheter, and with- drawing the urine direct from the bladder for the purpose of examination. In the female, gonorrhoeal urethritis frequently passes into the chronic stage, in which there are no subjective symptoms, the diagnosis depending wholly upon physical examination. A drop of thin milky pus may be obtained by pressure upon the urethra from behind forward, and the endoscope reveals the usual appearances of inflammation. The treatment, whether specific or otherwise, is con- ducted on the same general plan. It consists essentially in rest, a mild diet, the use of alkaline drinks, hot vaginal 1 lyS MEDICAL AND SURGICAL OYN.EC()^OaY. (loroln'H, warm sitz biiths uiul saiiim l(ixntivi\s. Much boiiufit inny bo derived from doucOiin^ tho urothrn with water as hot as can be borne. When the more acute syniiytomiH have subsideil, injections of sulpliate of zinc (1 to 509y, or of nitrnto of silver (1 to 4000), repeated four to six times u day, will often prove useful. The injection may be made with an ordinary uri^thral syringe, a pipette, or a reflux catheter specially adapted for urethral irriga- tion. In subacute or chronic cases, great benefit may be deriv(>d from douching the urethra two or three times a day, with hot water followed by the use of some astringent solution, while internally, oil of santal wood in ten minim capsules, or salol in five grain doses, may be administered. Granular erosion. This very troublesome, but fortu- nately rare affection may result from urethritis, or it may appear without any previous disease. The mucous membrane is found covered with young, imperfectly developed epithelium, the papillre hypertrophied and extremely sensitive, giving rise to most excruciating pain during micturition, and afterwards keeping up a most distressing tenesmus. In the treatment, mild measures do not accomplish much. The best results will follow dilatation of the urethra and painting the mucous mem- brane with a solution of nitrate of silver, a dram to the ounce, or of carbolic acid dissolved in glycerine. Strictures of the urethra are far less frequent in the female than in the male. They are for the most part acquired, narrowing being extremely rare. The causes of cicatrical contraction are chronic urethritis, most fre- quently gonorrhcBal; injuries during childbirth, or other forms of traumatism; caustic apjilications; and ulcers of syphilitic or t\iberculous origin. The most satisfactory method of treatment is by gradual dilatation, as practised in stricture of the male urethra, by means of dilators, similar to those used for dilating the urethra for diagnostic purposes. -, ■ DISEASES OF THE URETHRA AND BLADDER. HM) Prolapse of the urethral mucous membrane, ure- thral caruncle and venous angioma hnvo nlnmdy boon consiclorod wlion six^akiiij^ of (lisonsoH of tho vulvn, (Ohap. XTV). Urethrocele cousists of a PAOoulntion of tho middle portion of tho urothrr. It is formod, most fnuiuontly, by n bagging of tho inforior wall, tho ujipor wall (h^viating little, if at all, from its normal ijosition. Tho symptoms are, for tho most part, due directly or indirectly to the retention of a certain amount of urine in the sac. The residual urine becomes ammoniacal by decomposition, and finally jjurulont. The sac wall becomes inflamed and eroded, followed by general urethritis and perhaps cystitis. The sacculation is susceptible to the touch and ocular inspection, and when the pouch is large it protrudes from tho vulva. Trcdfmcnt. If the sac be of the diverticular variety, with little urethritis, it may be wholly excised and the resulting fistula closed by suture. In the presence of much urethritis the sac should be left unclosed, to facilitate drainage and the use of remedial applications. After the parts have been restored to a comparatively health}' condition, the fistula may then be closed. Irritable bladder. Under this heading may be grouped those conditions, either extrinsic or intrinsic to the bladder, which are not sufficient to induce organic disease, but which keep it in a constant state of irritability. The symptoms are such as to lead to a diagnosis of cystitis, but a careful examination shows the bladder to be normal, and we are forced to ascribe the symptoms to simple irritation of the peripheral nerves, either from direct or reflex causes. Probably tho most painful form of irrit;»ble bladder is that following plastic or abdominal operations. Following coeliotomy, the urine is genqrally of high specific gravity, has a heavy sediment, consisting usually of amorphous urates and phosphatic crystals, and is 200 MEIJICAL AN1> SURGICAL CIYN.ECOLOGY. cupjiblo of prodiu^iiig gn^nt vcsic-iil irritability. Afti^r Huch optirntioiiH too, tho uriiio is frcHiuoiitly diminiHluHl in (pinntity, ho ns to HUggost tho poHsibility of noi^hritis or obHtruction of one or both uretorH, n condition cnijabio of aggrnvating tho bladder already irritated by tho heavily charged urine. Irritability of the bladder will often be found to be prt^sent as a reilex manifestation, in diseases of the appendages, in dislocation of the bladder, in urethral caruncle, in i)rolai)se of the rectum or of tho uterus, and it often accompanies hysteria or other severe emotional disturbances. The diagnosis can only be settled by making a chemical and microscopical examination of the urine; the former reveals nothing abnormal, the latter a field laden with amorphous urates or phosphatic crystals. CYSTITIS. Cystitis in the female is of frequent occurrence. It may be either (trut(^ or chronie, local or (/cncral, and may vary also greatly in intensity and duration, lasting from a few days to many weeks The most frequent cause is the introduction of septic matter into the bladder by means of catheters, bougies, or other instruments. Cystitis, caused by extension of an inflammatory process, is a frequent result of vaginitis or urethritis, particularly of the gonorrluDal type. Mechanical injuries, retention and decomposition of urine, local chemical irritants, calculi and foreign bodies, are all potent causes of vesical inflammation. In the early stage of acute cystitis the mucous membrane is red and congested, but otherwise normal. Later the walls of the bladder become thickened and the mucous surface covered with pus, fibrin, and exfoliated epithelium, with, occasionally, small bleeding areas, where the epithelium has become detached. In tho chronic form the dangers are still more noticeable; the muscular and fibrous coats are greatly hypertrophied, the bladder cavity much decreased by the thickening and DISEASES OP THE URETJIRA AND HLADDEIl. 201 coiitraetioii of its wall, nml tho normal folds staiul out as promituMit rid^os, and may cvcmi assiuiu> a polypoid form. HtMiiorrlia^os occur into the mucous mtMiibranc and appear as dark occliymotic spots, wliich latc^r cliango to slate color from partial absorption. As a rule when, cystitis arises from habitual over-distiMision, the bladdi^r walls nrv thin and parohmi^nt-like. In these cases thii diphtheritic and croupous type of intlammation is most likely to occur. The entire mucous membrane becomes extensively involved, and is covered with a layer of Kbrous material, or false membrants which may be thrown off as a complete cast of the bladder. In more severe cases of diphtheritic cystitis, the membrane is composed, not oidy of necrotic mucous membrane*, but also of the muscular coat. In some cases the diphtlu^ritic process becomes locali/Anl and deep erosions or ragged ulcers result. The urine is usually intensely alkaline and heavily laden with mucous and urinary salts, especially the phosphatic, and are often dt^posited as tine incrus- tations on tlie ulcerated areas. Microscopically, there will be found a large number of leucocytes, or red corpuscles, pavement epithelium, isolated, or in clumps, and often large numbers of crystals of triple phosphates. As a result of the hypertrophic thickening of the bladder walls, the vesical orifices of the ureters may be partially occluded, and dilatation of the ureters, pyonephrosis or hydronephrosis may result. Symptoms. The symptoms will vary according to the cause, extent, severity and stage of the inflammatory affection. In the acute stage, pain, often severe, is felt above and behind the pubes, and radiating into the groin and down the thirhs. The desire to void urine is almost constant, and the act is attended by s-harp lacinating i ain at the base of the bladder. Follovang urination there is usually a sensation as though a few drops of urine yet L 202 MEDICAL AND SUUOICAL GYN.ECIOUHIY. romniiK^tl, ii (^(uiditiori soinor^'U^H so urj^iMit an to <'(iuho tlio pationt to remain for liourH on tlio ohainbor. Thoro in often n dull pnin in tho pcrin(>um, and proHHuro over the pubos will incrri'aso tho i)ain or tenderneHH tlu^re. Fre- quency of micturition iH an invariable .^ymptom, tlu^ frecpuMicy deijendin^ upon the dej^nn^ or Hta^e of intlam- mation. Hematuria is not uncommon in tlu» early wtage, and at times there appearH to be little less than pure blood voided; but as tho process becomes older it entirely disappears. In the acute form, the (piantity of urine passed may be normal, or slightly incn^ased, tho color unchanged, and possessing feeble acid reaction. After standing a few hours it becomes alkaline, and precipitates a diffuse sediment containing mucous, pus, and blood, in greater or less amounts. Sometimes the urine becomes ammoniacal and extensively offensive. The attack is often ushered in by a chill, followed by a rise of tempera- ture, which soon subsides, but in more severe septic or diphtheritic cases, tlu^ symptoms from tho onset indicate a very gravis condition. The patient falls into a typhoid state, with dry tongue, headache, vomiting, subsultus and delirium. Urination is sometimes obstructed by fragments of membrane, causing over-distention, or the ureters may be obstructed, producing total suppression and death from uraemia. In chronic cystitis, the symp- toms referable to the organ itself, and its contents, are similar to those described, but of a milder type. Tho urine contains pus, mucous, and exfoliated epithelium in large amount. On standing, it precipitates an extremely tenacious sediment, is neutral or alkaline in reaction, and sometimes fetid. A careful examination with the endoscoije will reveal the evidences of inflammation and ! j; the pathological changes present. Treatment. Especially important is the prophylaxis of vesical inflammation. A large proportion of cases arise from the introduction of pyogenic organisms into the UlSliASES OF THE UUETHUA AND ULADDlilt. 20,3 l)la(l(lor, honco too much cnro cannot be oxerciHtnl in clonnHinj:? and Htorilizin^ all inHtrumt>ntH uhihI for (examina- tion or tri'atmcnt. Tho first (^HHiMitial in rent i.. bed until the acuto HymptoniH have HubsicU'd. The diet should bi^ .instimulatin^; Huid and Hemi-fluid foods, such as milk, eggs, and light broths, are most suitable. Saliiu^ laxatives should be admiiiistered, and cnre tnkou to keep the large intestine free from fecal accumulation. Warm vaginal douches and em^mata nre very soothing, and hot sitz baths, with hot local compresses, will relieve thc! tenesmus and V(esical fulness. To allay the fever, and to render the urine unirritating when acid, the admiidstration of the following mixture will be found usef d, osijocially when combined with copious alkaline draughts: R. PottvHS. Citrat., oz. h.«; Spts. yEther Nit. , oz. i ; Tiiict. Aconit., drains iss; Atiuii' ad., oz. viii. M. Sig. — Tablewpooiiful in some water every four hourw. When the urine is alkaline it may be rendered acid *>y the administration of benzoate of ammonia, in tei- grain doses, every three or four hours. Salol is particularly useful in ammoniaeal decomposition, giving five to *ni grains every four to six hours. The same may be said of boric acid, in ten to tifteen grain doses. To control jjain, opium, belladonna, hyoscyamus, or chloral may be used with caution, and when prescribed should be given by the rectum. The first three mentioned are best administered in the form of suppositories, while chloral gives the best results when dissolved in two or three ounces of starch water, and administered as an enema. One of the most suitable preparations of opium to be given by the mouth, is Dover's powder, but bromide of soda, in twenty grain doses, and repeated every four to six hours, often acts more kindly for the relief of pain and tenesmus. Cannabis indica will often subdue the pain quite as effectually as opium, and with less injurious after effects. Irrigation 204 MEDICAL AND SUliGICJAL GYN.ECOi^OGY. of the bladder may be resorted to when the acute symptoms Imve subsided, or earlier if it is of septic origin. The most useful solutions for that purpose are three per cent, boracie acid, one-tenth to one-half per cent, nitrate of silver, ono-tenth to one-third per cent, permanganate of potash, one-half per cent, creolin, or one to ten thousand bichloride. In chronic (cystitis special attention must be paid to the general health, opium is to be avoided if possible, the bromides or cannabis indica being used instead to relieve tenesmus. Alkaline reaction of the urine should be cor- rected as in the acute stage and, if the urine be purulent, benzoic acid will be found of most service. Of the balsamic preparations there is none better than pure oil of santal- wood, administered in ten minim capsules every four hours. The treatment consists mainly in local measures, in the form of vesical irrigation by means of some simple form of irrigator. The quantity to be injected at one time must depend upon the character of the solution and the degree of vesical irritability ; in some cases an ounce is all that will be retained. The maximum volume shovdd rarely exceed two to four ounc^^s. the process being repeated several times until the bladder is thoroughly cleansed. The temperature of the tluid should be from UX)° to 105° F., and the irrigating process repeated twice daily. Besides the solutions already mentioned, other remedies have been found very serviceable, such as salicylate of soda, a dram to the pint; methylene blue, one to two grains to the ounce, especially in purulent cases; ichthyol in water, one-half to one per cent., especi- ally in gonorrhceal cystitis. In rebellious cases a two per cent, solution of rescicin may be employed. Iodoform, in the form of an emulsion (iodoform fifty parts, glycerine forty parts, mucilage of acacia ten parts), has been highly recommended, from two drams to an ounce being injected once a day. When treatment fails and the pathological DISEASES OF THE URETHRA AND BLADDER. 205 procoss j^rows worHo, it may be nooessnry to Hocuro coustaut drainage of tlie bladder by means of dilatation of the urethra, by tlie formation of a vesico-vaginal fistula, or by the use of a self-retaining catheter. The most satisfactory method for draining the bladder is by the formation of a vesico-vaginal fistula. KmmcVi^ operation. A sound is first passed into the bladder, and the vesico-vaginal wall steadied with a tenaculum and incised, after which a pair of uiunt-pointed scissors is entered and the opening tmlarged. To prevent the fistula from closing, the vesical and vaginal mucous mi^mbrane should be stitched together. Instead of the knife or scissors, the Paquelin cautery may be used. Vesical Calculi. Stone in the bladder is a far less common ilfection in the female than in the male. They are oftener of the phosphatic variety, roughened areas of the bladder wall being liable to become encrusted, and serve as the starting point for calculous formation. The stone usually lies free in the cavity; rarely it is encap- suled. When suspected the diagnosis can readily be made by the sound, by a cystoscopic examination, bj' digital exploration through the urethra, or by conjoined abdom- inal and vaginal palpation. Treatment. Calculi may be removed by way of the urethra, or by vpgiiml or suprapubic cystotomy. Small calculi may be removed through the urethra, after dilata- tion by n ^>ans of slender forceps. Larger, friable stones may be crushed with a lithotrite, and the debris washed out through a ^ "ethral speculum. When cystotomy is required, the vaginal operation is generally preferred as the simplest and safest. Foreign bodies introduced by accident, or intentionally, may be found in the urethra or bladder. The diagnosis may be made in the same way as in calculus, and their removal may be accomplished through the urethra. 20(i MEDICAL AND SURGICAL GYNECOLOGY. Neoplasms of the female bladder are of infrequent occurrence. They include papillomxi, mijxomd., jibvomd, mijoma, sarcoma, cpitlu'lioma, and carcinoma. The most constant symptom of vesical neoplasm is hematuria. Growths at ^' 3 vesical neck give rise to frequent and painful urination, and may interrupt the flow of urine at micturition, or cause retention. As a rule cystitis sooner or later results, followed by urethritis and pyelo-nephritis. An examination of the urine will show it to contain pus, blood, mucous, epithelial scales, neoplastic shreds and phosphates. The diagnosis is made by conjoined abdom- inal and vaginal manipulation, by the cystoscope, or by direct examination through a speculum. Treatment. Many small growths which are peduncu- lated, may be twisted off and removed through the urethra. If the tumors be sessile and spread out over the mucous surface it is best to resort to the curette. If the hemoi- rhage is free, or persistent, the bladder may be irrigated with hot water, and the vagina tightly packed with gauze. If the tumor be too large for removal through the urethra, vaginal cystotomy should be performed. If the tumor be malignant, it may be curetted and lightly cauterized, which will have the effect of greatly alleviating the patient's suffering. If the urination be painful and a high grade of cystitis present, the vaginal incision should be left open to allow for free drainage. Diseases of the ureters. The ureters are liable to ascending diseases from the bladder, to secondary involve- ment, or to descending diseases from the kidney, or to diseases which begins primarily in the ureter itself. One or both ureters may be affected. A serious att'ection of both ureters is incompatible with long life, as sooner or later .secondary changes occur in the kidneys. As a result of ureteritis, of whatever form, the ureter of the affected side becomes enlarged and may be palpated through the antero-lp.teral wall of the vagina in its upper third, where DISEASES OF THE UTERUS — MALFORMATIONS. 207 it gives to the finger the sensation of n rigid cord, or the feel of n round lead pencil. It is extremely sensitive upon pressure, and when so compressed produces a strong desire to urinate. An enlarged ureter can readily be felt by the rectum, from the broad ligament up as far as the pelvic brim. Further examination may be made, and much information derived, from the use of cystoscopy and the ureteral catheter and probes. The treatment should consist in curing the cause which produces the ureteritis; co-existing cystitis should be managed in the usual way, morbid urinary conditions corrected and the urine rendered antiseptic by salol. Fre- quent vesical douches and high rectal enemata of warm water should be employed. With the use of Kelly's spec- ulum *\\e ..i-eteral injections may be repeated, at suitable intervals, provided the operator has acquired the necessary technique for the introduction of those instruments. CHAPTER XIX. DISEASES OF THE UTERUS. MALFORMATIONS. All the important anomalies of the uterus result from arrest of development, and the nature of these anomalies depends, in a great part, upon the time at which the development was arrested. By bearing in mind the history of the normal development of the uterus, the many abnormal forms will be more readily understood. If the arrest of development occurs at a very early period, there will be simply a rudimentary bundle of muscle to indicate its situation, and in extraordinary cases there may be entire ab.senco of the organ. If there is arrest of f sion of Muller's ducts before the twelfth week, a more or less 208 MEDICAL AND SURGICAL GYNiECOLOGY. duplex uterus must result. If there is arrest of fusion in the two cnnnls after the twelfth week, a bicornate or sep- tate uterus will result. If the disturbance of development occurs at a later period, the uterus will retain a fwtal or infantile form, without longitudinal sej)- aration or distinct indi- cation of the duplex man- ner of its formation. For convenience of de- scription, malformations can thus be divided into those due to arrest of de- velopment during the first half of intra-uterine life; and those due to arrest of development after the first half of intra-uterine life. Malformations from ^ , arrest of development FiG.sg. — Development of the genito-iirinary tr.-ict . in the feniale.—w, «, kidneys ; e, i; ureters ; during the firSt half Of a, their orifices ii] the bladder ; 711, 7u, WolfTian bodies; {?,?, their efferent ducts; /,/», their mtra-Utenne life. Ah- openings into the urethra ; ^, ^'i ovaries ; »i,i>i, ducts of Muller ; 0, their common orifice ; 7', SCUCC OV VlKUIHCIlldVll ('('- iiro-genital sinus ; i/r, urachus ; c, clitoris. 1 ,• 11 1 velopmcnt oj the uterus. Complete absence of the uterus is an extremely rare occurrence, but rudimentary development is not un- common. There may be a small, solid, muscular body, without a cavity, or a partial excavation, or it may consist of a membranous sac. The vagina is usually absent, or consists of a shallow depression. Usually the tubes and ovaries are ill developed, and menstruation absent, but in cases where they are developed, periodical activity occurs in them, which, being unrelieved, causes much suffering. o DISEASES OF THE UTERUS — MALFORMATIONS. 20<) Uterus unicornis results from nn arrest of development, or from failure to appear, on the part of one of Muller's ducts. The developed side is situated entirely on one side Fit;. 60. — Uterus unicornis with rudimentary horn. LH, left horn ; RH, right rudimentiiry horn ; I.o, .ind Ro, left and right ovary ; l< Lr, and R Lr, left and right rouiui ligament ; LT, and RT, left and right tnhe. There is of the axis of the pelvic cavity, and it inclines quite strongly towards the corresponding pelvic wall no uterine fiiiidns. the uterine body end- ing in a cone-shaped projection, in which is inserted the Fallo- pian tube. Uterus hicornis and uterus didelplnjs result from the want of union of Muller's ducts immediately below those portions which normally forir the Fallopian tubes. The want of union may be confined to the neighborhood of the tubes, leaving a slight depression in the fundus, or it may extend lower down, dividing a large part of the uterus. Kit;. 61. — Didelphic Uterus and Divided Vagina : a, right segment ; /', left segment ; c, rf, right ovary and round ligament ; /, e, left ovarj; and roiuid liga- ment ; g, j, left cervix and vagina ; k\ vaginal septum ; //, /, right cervix and vagina. 210 MEDICAL AND SURGICAL GYNAECOLOGY. Fig. 62.— Uleriis Duplex. UtcruH <luph:r. The double uterus results from n wnnt of union of Muller's ducts ns far as the vagina. in consequence of which two uteri have developed. One Fallopian tube is attached to each uterus, and the vagina and cer- vix may, or may not be double. Uterus septus, or two- chambered uterus, arises from an imperfect union of Muller's ducts. The uterus is of normal shape, but the septum has not been obliterated. The vagina is apt to be similarly divided. When the septum lias been partially absorbed it is called nterus suhseptus. The diagnosis of these de- formities usually requires the aid of an anaesthetic. With the thumb in the vagina, and the finger in the rectum, the structures between them may be palpated, especially if the uterus is drawn down with a vulsellum, toward the vaginal outlet. A sound introduced into the uterine cavity will also aid materially in arriving at a correct conclusion. In such cases treatment is of no avail, except as far as reliev- ing painful or distressing symptoms. Where there is absence or rudimentary development of the uterus, removal of the ovaric^s may be demanded in order to secure relief. Fk;. 63. — Twci-chambered uterus. DISEASES OF THE UTERUS — MALFORMATIONS. 211 Atresia uteri. Just as has been shown that the hymen or vagina may be closed, the uterine canal itself, although more rarely, may be the site of atresia. The mucous membrane of the vagina may cover the whole vaginal portion, without forming any external os, or the cervix may form one uninterrupted muscular mass without bore. In such cases the vaginal portion may be well developed, or totally absent. In a bicornate uterus, one horn may be closed. Whenever the genital canal is closed, the symp- toms due to retention, such as amenorrhoja, painful menstrual disturbances, and the formation of a tumor will be present, hence tin; remarks made upon the symptoms, diagnosis, and treatment of atresia of the hymen and vagina are applicable to atresia uteri. When the atresia is situated in the uterus, however, the vagina can be exposed to its full extent and, in so doing, the uterus will be found to form a round elastic tumor above it. Dicujnosis. In pregnancy there will probably be a history of menstruation, and there will be present some of the well known signs. A fibroid forms a hard, nodular tumor, and often causes menorrhagia. Hematocele appears suddeidy, forms a broader mass, which pushes the uterus forward, and with these there will be a history, possibly, of previous menstruation. If the uterus is double the atresia is found much more frequently on the right side. In such cases the tumor will form in one uterus, while the other may perform the menstrual function quite normally. Treatment. If the uterus is single, an opening should be made through the cervix with a trocar, or blunt-pointed Fk;. 64. -Atresia of ihe cervix uteri. 212 MEDUJAL AND SURGICAL OYNiECOLOGY. forceps, ftiid (Milarged if uocessnry, and the contents evacuated witli the same care as already described wlien speaking of the treatm(^nt of atresia of the hymen, after which the uterine cavity must be irrigatt^d with an anti- sejjtic solution, and somc^ strips of iodoform gauze loosely inserted, and brought out through tlie now formed os. Later on the interior of the uterus may be curetted to combat endometritis and to hasten involution. If the accumulation is found in one half of a double uterus it is still an advantage to enter, if possibh\ tlirough the cervix; but often there is no choice, and the tumor must be punctured at its lowest point in the vagina. If the swelling cannot be reached from the vagina, cceliotomy should be performed, and the affected horn or whole uterus removed. Arrest of development during the second half of intra- uterine life. Fetal and infantile uterus. Some adult women have a uterus which corresponds in size to the uterus of a fcotus toward the end of pregnancy, or that of a young chihl. Other organs may be normal, but often the condition is combined with other abnormalities, especially of the ovaries. Pul)escent or con(/enitally atrophic uterus is one characterized by its small weight, often not exceeding an ounce, but the cervix and body have abo' t the same length. Sometimes the body of the uteras is well developed, but the cervix is small, pointed, or conical. In exceptional instances, the whole vaginal portion may bo lacking, while the rest of the vaginal apparatus is well developed. In those cases the vagina i^asses directly into the uterine cavity by a small constricted canal. Anteflex- ion of the uterus is often congenital, and simply a contin- uation of the shape of the uterus found in the fa3tus and in young children. The uterus may congenital ly bend to one side, the two Mullerian ducts not having kept pace with one another. DISEASES OF THE UTERUS— INJURIES. 213 CHAPTER XX. DISEASES OE THE UTERUS CONTINUED. INJURIES. On account of its position, tlui unimpro^unted utoriis is littlo exposed to iujurios from without, but is frequoritly the Hoat of injuries produced through t lo vagina. In gyn.'Dcological operations the uterus m occasionally wounded. Some uteri are so soft that they are easily penetrated by the sound or dull wire curette. When strict antiseptic precaution have been observed, and in- jection of an irritating tluid omitted, no evil consequence will probably follow a small puncture of the uterus. If there is prolapse of the intestine, cceliotomy should bo performed, the intestine drawn up and the opening closed in the uterus. Laceratio.i of the cervix. By far the most common injury to the uterus is that sustained by the cervix during child-birth, when it may be ruptured, or lacerated. The important pathological bearings of this accident upon disorders of the uterus have been appre- ciated only of late years. The credit of having recognised the significance of the lesion, and of having furnished a safe and efficient means for cure, belong to Dr. T. A. Emmet. Ctuiscff. The rapid forcing of the presenting part of the child through an imperfectly dilated cervix, brought about by early riipture of the membranes, or unusually severe and protracted expulsive efforts, is the cause, in a large proportion of instances, of laceration. More or less important parts in the causation of this injury are played Fig. 65.— Unilateral laceration of the cervix. 211 MEDICAL AND 8UR(tICAL OYN.ECOLOOY. by rigidity, faulty {lovolopmctit, cystic disonHc, cicatricijil iiidunitiou. and liyporplaHia of the corvix. The uimkillcd U80 of obstetric forceps may also be a cause of tln^ accidiMit. Lacerations are called pdrtial whiui the tear in the canal do(»s not reach the mucous membrane of the vagiim; complete, wlien the whol(> thickness of tlu^ cervix is torn. Complete laceration may be uniUiteral, hiUitenil, or stcUdte. Bihiferal lacerations are by far the most common, and they almost always extend from side to side, rarely from before backward. Unihiievdl lacerations may occur in any part of the cervix, but are more common on the left side, owing, it is said, to the frequency of the first position of the vertex. Stelldte lacerations, while sometimes not deep, are often of considerable extent. In regard to frecjuency, it may be said that but few women confined at full term Fig. 66.-Bilaterall.-.ceration of the cervix, wilh CSCapC withoUt SUStaiuiug ever.ionoflhecervical,nucousn,eml,rane. ^^j^^^ j^^.^^^, ^^ ^j^^ ^^^^j^^ be it ever so slight, but the proportion of rents likely to produce pathological symptoms, may be put down as somewhat less than fifty per cent. After laceration, the torn surfaces, bathed in the lochia, rarely unite, and in that condition will act as a source of irritation, jirevent p r involution of the uterus, and will eventually indue enlargement and thickening of the uterine tissues. In some cases the flaps become enor- mously hypertrophied by the formation of new connective tissue, so as to resemble small fibroid tumors, and have been mistaken for such. Relaxed ligaments with uterine displacement — especially when it is associated with a lacerated perineum— and congested ovaries and tubes, in A jfiiim mm^!il'!l!l^l^*" ^ i f, %% i -((//)(/, i*ff'j^B \ 1 ~a 1 lA // ^ DIHEASES OF THE UTERUS— IIJJUUIES. 215 tlu'ir turn, follow. OccnHiomilly imtJirc H(>t'ins to inak«^ uii effort to rc^pair tlui hKu^rntioii by tlu^ t'orinntioii of a hirgo amount of granulation tissui^ tilling up tho angloH of tho rent. Ill process of time this granulation tissui^ becomes converted into a hard dense cicatrix, compressing terminal nerve Hlaments, a condition thouglit by many to be the cause of the reflex symptoms so commonly met with in long standing cases. When the lacerated cervix does not cicatrize, the separated lips evert, the mucous membrane lining the cavity is rolled out (ectropion), its epithelium is gradually rubbed off, and a hyperplasia of cysts and papilhu take place, giving rise to a profuse, discolored, glairy discharge. This hyperjbmic a n d hyperlastic condition often extends ujjward to, and often beyond the internal os, and cervical and corporeal endometritis result, so that menorrhagia may be present. Attention has been calhid to the frec^uency with which epithelioma of the cervix has been found in conjunction with laceration, and it is undoubtedly a fact that a very large proportion of such cases are preceded by such traumatism. Symptoms. Tho symptoms which attract the attention of the patient will probably be a dull pain in the back, sacrum, and lumbar regions; bearing down or dragging in the pelvis; pain in the ovarian regions, hips and thighs; leucorrhoea; menorrhagia; and occasionally sterility, or habitual miscarriages. Accompanying these there will generally be found progressive loss of health, and a most decided state of anaemia. Neuroses of the eyes, head, stomach, and bowels are also frequently met with; to Fig. 67. — Multiple stellate laceration of cervix. 21() MEDICAL AND SUUOICAL <lYN.ECOL()GY. which hyHtc'^-icnl Hymptoms may ovon bd mldiHl. On pnHHiii^ the Hiig(^r into i\w vagina, tho hicoration in oawily ro(M)gni/-('(l. In tho angh'H of tho ront hanlonod tinHUo is foit, i)roHHuro upon whicli product^H [)fiin, wlii(!h ofton rndinti^H into tho pt^lvis and down tho thighs. Tlio Hurfnco may fool rough and granuhir from tho largo follioloH, or volvoty and soft from orosion. Kxamination by spocuilum dooH not givo mu<Oi information, furthor than to bring into view tho granular or orodod Hurfaco, tho whito or yollowish dlHchargo with whicih it is covorod, and tho hyportrophiod condition of tho cervical flaps. Indications for trachelorrhaphy. Tho moro oxistonco of a lacc^ration does not call for radical operation. Tho indications for that moasuro depend entirely upon tho depth of tho rent, tlu^ degree of oversion and amount of orosion and hyporijlasia of tho torn lips; tho intensity of tho symptoms depending upon it, and by tin* improbability of these .symptoms b(ung permanently cured by other than radical treatment. The treatment of laceration immedi- ately after their occurrence has boon strongly advocated by some, but such a procedure has not gained in favor with the majority of obstetricians, owing to the difficulty in estimating tho extent of laceration, the relation of the parts, and the ability to bring them together properly. Prcliminarji frcafmcnt. Some have thought it advis- able to cure orosion. when present, before operating, but such a procedure does not seem necessary. If there is extensive cystic degeneration, it may be treated for a time by local applications, but generally both these conditions can be managed at tho time of operation. Preparatory curettage of the uterine cavity has also been advised when endometritis exists, but this too is un- necessary as it can be done just as effectually before beginning the denuding process. The operation of trachelorrhaphy may be performed by placing the patient in the dorsal position, the legs DISEASES OP THE UTER'JS— IN.Il'KIES. 217 elovnt(Ml, mid kepi in poHition by Clovcr'H crutch, nrul n Sims" brofid-bliKlccl Hpcciilum itiHcrtcd. A very convciiii'iit Hpcculurn for that niid other opi nitioiiH on tlie utcruH, when the pnti(Mit is in tlic dorHnl i)o.sition. in oi.o known (iH Fidc^bohl's. It is HO curved at the junction of the haiuUe jind the blade that it will not slip out. and. by HUH[)ending a HufficicMit weight to the handle, the neceHsary retraction is made on the perineum, and the necessity for an assistant to hold the si)eculum df)ne away with. Sumo prefer oijcratinj^ in Sims" position, claiming that it ^ives much mon> room for manipidation and for the piissage of the needles. However the choiv'^e of position and speculum is largely .^ matter of <»du- cation and habit. Th > best needles to employ are heavy triangular or bayonet-pointed, straiglit. or curved Slightly at tlie point (Emmet's). The suture material is a matter of in- p, -„ vii m- .^ „i,.n, rlG. 00. — Kdebonl s speculum. difference: silver wire, silkworm, silk and catgut are all used, If the perineum is to bo closed at the same time, it is best to use some material which will be absorbed in the course of eight or ten days, such as chromic catgut. Unless contraindicated from some good cause, it would be preferable to use catgut under all circumstances, as most patients have a great dread of what they look upon as another operation for the removal of the stitches. After deciding upon the amount of denudation neces- sary, the edge of one lip is seized with a tenaculum, and a Hap raised from the surrounding tissue with scissors or scalpel, the cutting process being continued until tlie angle is reached, where it may be necessary to go (piite deeply to remove all the cicatricial tissue. After the angle has been passed, denudation is made in a similar manner on the other lip, and completed by uniting it with 218 MEDK^AL AND SURGICAL GYN.flOOLOOY. the previous incision. If n second laceration exists on the opposite side, it is to be denuded in the same way. Some use a peculiar pair of scissors devised by Skene and known as " hawk-bill " scissors, wliich denude the margins and take out th(> cicatrix at one and the same time. Hemor- rhage can usually be controlled by hot water, but if very troublesome a stitch may at once be jjassed through both lips of the cervix, above the angle, and tied so as to com- press the circular artery. The sutures are next introduced, the first being passed through the upper angle of the rent, and each successive one through the whole depth of each Fir,, fig. — Surfaces Jenuded and sutures passed. Fk;. 70— Same with sutures lied. lip, until all the sutures needed for that side have been inserted. Next the sutures on the opposite side are similarly inserted, if the denudation has been bilateral, after which they are tied, the highest one first. A sound is next introduced into the cervix, to mrke sure that it is sufficiently patulous. After flushing and drying the vagina, it may be lightly packed with strips of iodoform gauze. DISEASES OF THE UTERUS — METRITIS. 211) CHAPTER XXI. DISEASES OF THE UTERUS CONTINUED. METRITIS. According to the etymology of the word, metritis means iriHnmnintion of the uterus, but tlie classitiontion of the various patliolo^ical conditions included under that heading is not so easily disposed of. When considered according to the progress of the disease, it is designated by the terms acute and rhrouic ; when classifi(^d according to location, it is divided inio cervical rw\ corporeal: when looked at from r^a etiological standpoint, it is designated by the terms pucrperah post-puerperdl, <ionorrh(ral, exanthematous. and traumatic; or when from a patho- logical standpoint, (jrannlar. fuiajous, and ulcerating. For convenience of description the various forms of endometritis may be classified as follows: 1. Acute metritis and acute endometritis. 2. Chronic cervical endometritis. 3. Chronic corporeal endometritis. 4. Chronic metritis, or subinvolution and sclerosis. ACUTE ENDOMETRITIS AND ACUTE METRITIS. By the term ; :ute endometritis i.s meant acute in- flammation of the endometrium, and by the term acute metritis, inflammation of the walls of the uterus, but as inflammation of the endometrium can scarcely occur without the uterine walls participating to some extenc. nor can inflammation of the walls occur v .thout participation of the mucosa, the description of the two. as distinct diseases, would be usel(>ss. at least from any other *han a pathological standpoint. When the inflammation affects the mucous membrane more than the walls, it is termed endometritis; when it produces extensive changes in the walls, it is called metritis. 220 MEDICAL AND SURdUUL (lYN. ECOLOGY. (^(iiixcs. Tlu' luost poti'ut fuiisf )lriH(^s from bnctorinl invasion from iafccti'd Imiuls and instruments (luring parturition, abortions, operations and examinations: during uterine and vaginal douches; from retained deoidua after abortion: or from invasion of the gonococcus. Infc^etion may arise seeomhtrily from foreign bodies K'ft in the uterus or vagina, such as stem pessaries, tents and tampons. Violent congestion of the uterus, such as occurs in acute suppression of menstruation, and the prolonged conges- tions growing out of flexions and versions, are prominent factors in these lesions. Retained menses, arising from stenosis, catching cold, and other influences, such as over- exertion, excessive coitus, or traumatism, acting during the menstrual congestion, increase the natural hyperaMnic condition to such an extent as to interfere with its natural subsidence, and tend to engorgement and inflammation. Specific germs of the exanthemata appear to be capable of inducing mild inflammatory changes upon the mucous membrane of the entire uterus, seeming to act upon it as upon other mucous tracts (the conjiinctivfv for instance during measles), and in a similar manner tend to disappear with the subsidence of the disease. Pafholoc/ii. In acute endometritis the extent of the lesion will de})en(l upon the virulence and activity of the infecting element, and will vary from a mild injection of the endometrium to a deep and wide spread inflltration with the products of inflammation. The material found bathing the infected surfaces will also depend upon the same influence, being in mild cases merely a muco- purulent fluid, in others purulent, or even bloody. The normal red color of the endometrium is dee[)ened propor- tionately, and may he almost livid: the mucous membrane is thickened, softened, even pulpy at times, and easily torn from its attachments. The interglandular spaces show an increase of round cells, which, in extreme cases, are so abundant as to give the whole surface the appearance of DISEASES OF THE I'TERUS— METRITIS. 221 granulation tissue. The epithelium is iutiltrated, and even destroyed in certain places, and the cilia in general may be said to have shared a like fate. The implication of the muscular coat (metritis) is slight, except in some cases of gonorrhceai infection. There is swelling of the muscular fibres, increase of cell formation in the interspaces, and infiltration with a serous or sero-purulent tiuid, by which the uterus becomes more or less enlarged. Minute extravasations of blood are apt to be found in spots, particularly near the mucous membrane. Sijiujdoiiis. In the simple form they may be compar- atively insignificant. There will be a sense of fulness in the pelvis, more or less pronounced, if there be arrest of the menstrual tlow. accompanied by fret^uent micturition and rectal tenesmus. In more severe cases the symptoms are more decided. There will be dull deep seated pelvic pain, backache, and aching down the thighs, increased by motion or by the evacuation of the bladder and bowels. Slight febrile reaction will also be present. In septic cases a chill, more or less pronounced, ushers in the general disturbance, accompanied by a rapid and decided rise of temperature. Should the intlamnuition extend to the peritoneal covering (perimetritis), the phenomena of local peritonitis will be directly added; if it extend through the Fallopian tubes the evidence of salpingitis will appear, and from either of these general peritonitis may arise, or other extreme symptoms indicative of general septic absorption. The chief physical signs are tenderness over the pubes, and tenderness of the uterus, elicited by bimanual and vaginal pressure. The cervix will be found patulous, softer, larger, and redder than natural, particularly about the external os, and exuding from it a tough, glairy, opacpie secretion. When the uterine walls are afflicted, particularly in septic iuHammation, the entire organ is enlarged and softened, and then' will be noticed flowing 222 MEDICAL AND SURGICAL GYXJICOLOGY. from the os a thick, ichorous, bloody discharge, which may have the odor of decomposition. Fro(iiiosis. Ill the simple form life is rare'y en- dangered, but in the septic forms it commonly is, either through general peritonitis, or from general septic infec- tion. The integrity of the organ is always tnidangered to an extent proportionate to the severity of the inflammation; slight, if any, in the milder forms. I»ut decidedly pro- nounced in the graver ones. The dangers result in part from the chronic changes in the uterus itself, and in part from the implication of the adnexa. JJidtinosis. In the non-pregnant uterus this lesion is indicated by tenderness of the organ, and by discharge from the cervix, taken in conjunction with the comparative suddenness of an attack developed in connection with an acute suppression of menstruation, with a prior vaginitis, or with some such cause as an operation upon the cervix, or the introduction of a sound. After a ortioii or labor it is commonly indicated by a chill, followed by rise of temperature, and temporary arrest of the lochia, with its subsequent reappearance, and on reappearance often has an odor of decomposition. The organ soon becomes tender and subsequently loses its firmness. Such cases may be confounded with typhoid or malarial fevers. If malarial, quinine will control it absolutely ; if typhoid, differences in the rise and fall of temperature will assist in making a diagnosis. In all cases when in doubt, it is wiser to assume the presence of septic infection. Local- ized mastitis is another source of error, but a careful examination of the breasts will readily correct that. Tre^diucnt. From what has been said of the etiology of the disease, it will be readily understood that the treat- ment will vary according to the nature of the case. The milder forms are best treated by rest in bed, purgations by means of salines, by mild febrifuge treatment, and by hot vaginal douches supplemented by hot fomentations, DISEASES OF THE ITERUS — METRITIS. 223 and counter irritation over the abdomen. If there is no serious objection to physical examination, local depletion may be accomplished by free scarification of the cervix, followed by a warm vaginal douche. As soon as the more acute symptoms have subsided, boro-glyceride tampons may be i^laced against the cervix daily. When it arises as a result of vaginitis, particularly that form met with in gonorrhoeal infection, it will probably be necessary to irrigate the uterine cavity with a solution of bichloride (1 to 3000), dilating the cervix sufficiently for that purpose, if it is not already patulous. In the septic forms prompt and energetic measures are demanded. If the result of negligence in failing to keep up proper aseptic precautions during operations or examinations, the cavity of the uterus should be freely irrigated with bichloride solution and packed with iodoform gauze. Should a wound exist, the lips had better be separated and kept apart by strips of the same material. Should the case be one of septic inflammation following abortion or labor, radical surgical measures should be promptly applied. The cavity of the uterus should be curetted, all debris scraped away, and the uterus fully and tirmly packed with gauze. The vagina must then be packed loosely, tirst around the cervix and then down to the introitus. The packing of the vagina should be removed at the end of twenty four hours and warm stt^rile douches given. At the end of forty eight hours the uterine packing may be removed and, if no fever be present, the cavity of the uterus need not again be entered, but if the temperature is still elevated the cavity should be irrigated and fresh gauze inserted. Even though the case appears desperate, the cleansing and draining should be continued, for not unfrequently it yields in the end. The gravest surgical perplexity arises in connection with further operative procedure. The removal of the infected uterus, either through the vagina or by cu;liotomy. offers the surest 224 MEDICAL AND SURGICAL GYNJICOLOGY. relief, could the nhock of so grnve an operntiou be controlled. Patients infected with a general sepsis rarely withstand any grave abdominal, or even pelvic operation, and although many successful cases have been reported, it is still looked upon by many as justifiable only under desperate conditions. Stimulated by the success of serum therapy in diphtheria and in a few other infectious diseases, effort has recently been made to procure a serum that will be antagonistic to streptococci and antidotal to the products of their activity. This form of medication bids fair, thus far, to be of great service in puerperal infection. Few reports have yet been published regarding the use of the serum antitoxine, but those that have been, serve to prove that in cases of infection due to poisoning by the streptococcus alone, the streptococci antitoxine, when used early, is a curative agent of great value, but in mild cases of infection in which, besides the streptococcus, the colon bacillus, the bacillus fetidus, the staphylococcus, the bacillus pyocyaneus, and other micro-organisms are found, this antitoxine has little or no beneficial effects. I" si ENDoL'iiKvicrr: Endocervicitis is recognized oy various synonyms, such as cervical endometritis, cervicitis, cervical catarrh, trachelitis, and erosion of the cervix. Inflammation of the cervix exists independently of like lesions in the body of the uterus, its position exposing it to disease to a far greater extent than the deeper portions of the organ, and as such requires separate consideration. In acute processes, especially those derived from gonorrhcBa and septic infection, the two parts of the organ are so often involved together, that it seems unnecessary to consider the lesions of the two separately. The appearance pre- sented by the cervix in acute inflammation has already been referred to. The mucous membrane of the canal is DISEASES OF THE I'TERrs— METRITIS. 225 swollen niid softened, nud its cavity filled with a viscid muco-puruleiit secretion. The appearance presented by the deeper portion of the cervix is also, in all respects, similar to that met with in the body of the uterus. This does not apply, however, to the chronic forms of the disease; the inflammation being of a lower grade of intensity, more strictly confines itself to the cervix, without involving the d(H>per parts of the uterus. Cdiiscs. Chronic endometritis may arise from a variety of causes. Impoverishment of the blood from chlorosis or some other form of malnutrition, producing lowered vitality, strongly predisposes to the disease. Infection from the vagina, such as from gonorrheeal or purulent vaginitis, from the entrance of foreign bodies or septic germs into the vagina, from examinations, operations, coitus, masturbation, pessaries, and vaginal douches, may infect the cervix directly. Laceration of the cervix is by far the most frequent cause, and along with it may be mentioned displacements of the uterus, opt^rations upon the cervix, strong local treatment, and attempts at abortion. P(itliol<Kjij. Endocervicitis is cliara(^terized by hyp«r- femia, thickening of the cervical mucous membrane, and hypersecretion of the glands. The mucous may be unaltered, or it may be thicker than normal and excessive in quantity. If the congestion is long continued, exfoliation of the epithelium progresses faster than its replacement by the development of new cells, so that the membrane becomes covered with young epithe- lium, giving it a reddish color (si niplc erosion). This disturbance not only involves the mucous membrane of the canal, but extends outward from the os, about half the thickness of the walls of the cervix, giving rise to the condition once described as ulceration. As the process advances the mucous membrane becomes thick- ened by proliferation of the areolar tissue, so that it becomes too large for the surface which it covers, and is 226 MEDICAL AND SURGICAL GYNAECOLOGY. thus thrown into a multitude of minute folds, rugosities or wrinkles. To this condition the name papillary erosion has been given, as the small folds look like papillee. The glandular pockets formed by these folds reach down to and between some of the bundles of muscular fibres. These pockets, as well as mouths of the glands, may become closed and filled with secretion, forming cysts of all sizes up to that of a pea, and give rise to that condition called follicular erosion. When the hyper- plasia is extensive, the thickened mucous m.nnbrane Fig. 71. ^Erosion of the cervix, — a, ^.simple papillary erosion ; c, follicular slightly enlarged. pverfills the cervical cavity, dilates the external os and rolls out into view, giving the cervix the appearance as if the vaginal portion were partly clothed with cylindrical epithelium. This condition is called eversion or ectropion. When the structures are more actively affected, or to a greater depth, other changes are produced. The mucous membrane throws out largo projecting folds which may or DISEASES OF THE TTERUS— METRITIS. 227 may not develop into mucous polypi or polypoid masses. The occluded and cystic pockets and Nabothian glands may project on the surface, and, if numerous, may occupy half the thickness of the cervical walls, and produce a condition known as cystic ((('(/('ucrotioH. As a result of these changes all of the glandular structure may be finally destroyed, and sclerosis, resembling senile atrophy, result. Sijmphms. When mild, and of short duration, the case may be free from all symptoms except a vaginal discharge. This discharge, however, is in some degree characteristic; it is not continuous, nor. in the absence of vaginal implications, abundant. It is viscid and jelly-like, and transparent, opaque, or yellowish according to the amount of purulent admixture. In the presence of cervical laceration, it is mixed with a un^re muco-purulcnt discharge, and is at the same time more constant. In deeper seated implication of the cervix there will be, in addition to the discharge, dull lumbo-sacral pain, and, perhaps, reflex nervous symptoms. On making a digital examination, a softened ring is felt around the os, and, if extensive cystic degeneration with eversion exists, the cervix will be felt enlarged, soft, and elastic, with perhaps isolated distended follicles, like buried shot under the surface. Laceration of the cervix, with extensive erosion, may simulate carcinoma, but by examining under the micro- scope a small strip removed by the knife, it can be readily differentiated. A profuse serous and blood-stained leucorrhoea is almost always characteristic of cervical carcinoma, and so are the hard exuberant cauliflower excrescences springing from the vaginal aspect of the everted cervix. Treatment. As the disease consists mostly of an inflammatory degeneration of the cervical mucous mem- brane, efforts should be directed to produce an alterative influence uix)n that membrane; and as it is often associated 228 MEDICAL AND SURGICAL GYNJICOLOOY. with H depraved condition of the system, further efforts must be made to iitt'ect favorably the general health. Every function of the body should be regulated by proper nu'unH, and vegetable tonics, mineral acids, and preparations of iron administereil, and daily exercise and good healthy nourishing food provided for. Particular attention should be paid to the proper regulation of the bowels, for which a ferrugineous tonic with a cathartic may be prescribed, as in the following: — R. Magiiewiif Sul|thati.M, oz. ii ; Ferii Sulphatis, mn. xvi ; Acid Sulphurio, Hil., dram i ; Tinct. (ieiit. Co., oz. i ; Elixir Siniplici.s, ad., oz. xvi. M. Sip. — Two tablespoonsful in half a tumbler of ice water each morning. R. Hodii' et I'otass. Tart., oz. ii ; V^ini ferri amari, U.S.I), oz. ii ; Afid Tartaric, dramis iii ; Eli.xir Simplicis, oz. iv ; A<iii!e ad., oz. xvi. M. Sig. — Two tablesiKJOMsfuI in half a tumbler of water each morning on rising. Locally the source of irritation must be remove'' and the ett'ects counteracted by mild antis(^ptic and astringent applications. Endometritis and vaginitis, if present, should be treated, and uterine displacements corrected. Of local applications, the most important is the vaginal douche. The water may contain permanganate of potash (1 to ;}OUU). carbolic acid (1 to 100), or bichloride (1 to 5000), when for antiseptic purposes; and if required for an astringent effect, sulphate of zinc, three grains to the ounce, sulphate of copper, two grains to the ounce, or acetate of lead, five grains to the ounce. Vaginal tam- pons, saturated with boro-glyceride, or glycerite of tannin, or a ten per cent, solution of ichthyol, may be introduced by the patient every night, and removed the next morning before taking the douche. Local applications, such as a ten per cent, solution of sulphate of copper, or crude pyroligneous acid, may be DisKAsiis OF Tin: iTuin's mktkitis. 229 made tliroiij^h a Hpcculum. twice r tl>r(H> times weekly. In Home eaw^H the applic-ntioii. once in a wiu'k or ten (lays, of strong ('arlM)lie acid, or tincture of iodine, or of the two mixed in ecjual parts, seems serviceabh*. follow(>d at once by the api)lication of a horo-Kly('cri(h' tampon. In all cases the os should be w«^ll dilated, the mucous wiiu'd away, and the application made frei^ly to the tMitire cervical cavity and to the vaj^inal portion, by means of an api)li- cator, or by for(H«[)s wrapju'd with cotton. When the cervix is much indurat(*d and studd(^d with retention cysts, Kcaritication is very useful. It acts by depletion and allows the escape of tl)e inspissated mucous. The punc- ture should be permitted to bleed a little, but if the hemorrhage is too free it may be checked by absorbent cotton Hrmly pressed against the cervix. Subseiiuently tincture of iodine, or carbolic acid, should be applied, and a small boro-glyceride or ichthyol tampon placed under the cervix to maintain the antiseptic and alterative acoion. In cystic degeneration, the cysts must be laid open, and carbolic acid or tincture of iodine applied. In very chronic cases, where there is extensive degeneration of the mucous membrane, it has been recommended to destroy it by means of strong caustics or escharotics. but their use is dangerous, it being impossible at times to limit their action, and. besides, they are likely to [jroduce cicatricial contraction. When glandular tissue is to be destroyed, the most efficient way of doing so is by excision of the mucous membrane, after the manner recommended by Schroeder. CHRONIC" CORPOREAL ENDOMETRITIS. Like the cervix, the body of the uterus is liable to chronic inflammation of its lining mucous membrane. Causes. It may follow at once upon an attack of acute endometritis, or metritis; or it may be brought about by causes which delay or disturb involution after abortion Wiiil l(;f 1/ 1 ^v^inuy wt.,t;:;,';;l,,r':;;rf ''" °"™ -<-«• "vantm, „„,| „„„,, j,;^,,. "''''"'''' «'™™i« o( el,e cervix '- -"ori,,,, „„,„„,;,• „'^.„^:''';'""»i in.,.rf„r,.„co wm,' •x'lii'vo,! to bo pr«l,,,J„ '^"'™"" »"'! <l.-bilitv arc. "f 'I- -™lo.m..ri„ ™r" """'' "■"""'. ""'I '.yi-rpta J (ithohxni To f 1, , , ■ '-woll™ „;„, ,„f, "" ""kec ..,e tho muoo„« „™br„„e "'tl. Lore „„d „„.„, I J,,"'"; " ^emblos cjuinco jolly muscular coat participates i,^ ,7 " "* """'' """ ">e projections „„„ depr"^ „, J"'^'"'"'' P"'-"'inK alternate go«.t.e8„„yb,„./'« These projections or fu„. or they „„y b, veritable poly"" ""'?"'' "'o^'"""! form. In other cases small cysts'T 1^7'''' ™ P""»"o"l»ted. bodies met with in the ™'""'''"« »mewl,„t similar "rophyofthemuco mlh:™!- "" f™^"'' ^•''«" « smooth and glfetenin^.""";, ''",?"""'• "-surface "troph.c changes, is thin am '""''" '"•'' oxtonsive MicroscoDienI „ »»'' tr»"«P»rent. three forms l^^L::Z^t """"™'"'- Presents i„ '" o- "nd the s„me';X: T'"''' "' "" "■»""•«" Jn the infcrsfifi'n/ f i transformed into cicatr IT , '"'"Klandular tissue is «h.nds, causing thet™ "r; iTn?''''"'' """"'"^^ "- obLteration. I„ other'^„ "i thev"""""""^ """P'* P'aces they are converted into DISKASIiS <)!' THK UTERI'S - MKTUITIS. 231 cysts, in number proporti()iiat(> to the doj^rrnof connective tissue development. In extreme cases, of lon^ durntion, the inu(H)us m(>mV)rane becomes atroi)liied. and is converted into n thin hiyer of s(^h>rosed connective tissue. Embedded in this sch^rotii! tissue, lien- and th(<re are cyst cavities, the remains of constric^ti^l and (h'^i'iierated glands. Thi^re are two forms of th(^ j/hnidnhn' varii^ty. one in whicli the glands are incr(>ased in their dimensions {hjipct'ivophic): and another in whi(Oi there is actual increase in the ({uantity of gland tissue (hijitcrpldstir). In the former, the utricular glands no longer appear as a series of straight tubes, but are twisted, elongated and arranged spirally. In the second form there is not only increase in the number of the glands, but they are dis- torted, and here and there present lateral prolongations or diverticulre. Chronic poli/poi'tl endometritis is a combinn*'on of the interstitial and glandular varieties, with marked cystic formation, together with great increase of the vessels, both in number and in dimensions, and an increase of the interglandular structure. In some cases the whole mucous membrane is thickened, in others only portions, while in others the glands are chiefly affected and project as polypoid masses. The great increase in vascularity accounts for the clinjcal behaviour of this variety, menor- rhagia being the st. "iing symptomatic feature. In con- nection with this la.st form of endometri'Js. there is a variety resulting from the retention of portions of the decidua. after abortion chiefly, but occasionally after labor at term, cvdowfirififi deciihuilis. The retained tissue presents itself as projectionr. from the general surface of the mucous membrane, and is soft and easily detached. Microscopically, it is diff'erentiated by the presence of degenerated decidual tissue surrounded by a mass of small cells. Clinically it presents symptoms of the polypoid form by the profuse menstrual flow. 232 MEDICAL AND SURGICAL GYN.13COLOGY. Symptoms. The Hymptoms of (nidometritis vary to a great extent, according to whether the case be a severe one or not. They may scarcely attract attention, or they may be so pronounced as to render life a burden. Mcnovrhdf/id is by far tlie most common symptom. The flow may be profuse and clotted, persisting at times longer than normal, and at others contini:i'\tr during the larger part of the intermenstrual i^eriod. particularly in the fungous or Ijolypoid form. LoucnrrlKrd is nearly always present between the periods, although in old cases it may be so sliglit as not to attract the patient's attention; after sclerosis of the mucous membrane has resulted it may be absent altogether. The discharge consists of a thin clear mucous, or muco-pus. As it appears at the vulva it is rnilky white, creamy, or greenish in color, owing to its having mingled with cervical and vaginal discharges. When mixed with blood it acquires a pink, brown, or smoky tint. Pain of some kind is rarely absent. Lumbo-sacral pain is a prominent feature, and it may radiate down the thighs. Dull, persistent, deep seated pelvic pain is also present, extending i^erhaps to the perineum. If the organ is enlarged and anteverted there will be frequent micturition and vesical distress; if retroverted there will be mechanical constipation, with pain along the sciatic nerves. Unusual or prolonged exercise, especially jolting over roiigh surfaces, increases the pain. To the local discomforts, neuralgic pains may be added, such as occipital, intercostal, lumbo-abdominal. and facial neural- gias; coccygodynia. gastralgia. meteorism. and similar reflex symptoms may also be prestMit. Sfcnlifi/ is a common accompaniment, owing to the several obstacles to impregnation, and to proper decidual growth. Sometimes the ovum does not reach the uterus, or it may be destroyed by the secretion, or by forming no attachment to the endometrium. li Li DISEASES OP THE UTERUS— METRITIS. 233 Phi/sical sifpis. Palpation shows nothinj^ but a symmetrical enlargement of the utjrus. Generally it is tender on pressure, particularly when the cervix is touched. In th'3 absence of complicating diseases of the adnexn, of the utero-sacral lig' .lents, or of the peritoneul surround- ings, the uterus i& .reely movable. The introduction of the uterin"^ sound is ordinarily, though not invariably, attended by pain, and in most cases a sensitive spot is met with at the internal os. The canal may measure from three to four inches in length, but the sound conveys little information as to the state of the endometrium, unless it be by the induction of bleeding in the decidual or other hemorrhagic forms. Didf/nosis. Pregnancy has been mentioned as a con- dition with which the lesion may be confounded, but a proper examination and consideration of the signs and symptoms will readily determine which condition is present. It may be mistaken for commencing fibroid disease. If tlie disease be interstitial, and more particu- larly if it be subperitoneal, conjoined vaginal and rectal examination will reveal inequalities on the outer surface. If the growth be wholly submucous, it may be detected by the introduction of the sound. The hemorrhagic: form may be confounded with abortion, but the early history and a careful examination of the discharges will suffice for differentiation. The diagnosis of certain forms of corporeal and cervical inflammatory lesions from carcinoma is a matter of pressing urgency, for, to be of any service, diagnosis must be made early. Here the free use of the sharp curette and a careful microscopic examination of the scrapings will assist materially in clearing up the difficulty, and should never be omitted in doubtful cases. Pro(j)i(>sis is usually favorable as far as life is concerned. Taken early, all forms yield readily, but after extensive changes have taken place permanent cure is uncertain. Of all forms, polypoid is the most obstinate, and it also is 284 MEDICAL AND SURGICAL GYN^C()Lf)GY. tho form which appears to tend most frequently to carcinomatous degeneration. Every form tends towards the induction of intlammation of the adnexa and peritoneum. Trcahneid. Cases witli profuse menorrhagia, unac- companied by tumors or diseases in the adnexa, pelvic peritoneum, or connective tissue, but with considerable thickening of tho mucous membrane; fungous endome- tritis, and in general all cases that have resisted long continued local treatment, should be submitted to thorough intra-uterine curettage. After completing the operation, it may be considered advisable to touch the surface over with strong carbolic acid, or tincture of iodine, or iodized phenol, and to pack the cavity lightly with strips of iodoform gauze. Subsequently the treatment should be along the lines already enunciated in conjunction with the treatment of acute metritis. Subsequently, an effort must be made to keep up the free drainage through the cervix already established, which maj'^ be done by occasionally passing a dilator and introducing a few strips of gauze into the cervical canal. Boro-glyceride or ichthyol tampons may be inserted by the pAtient once a day, and allowed to remain for twelve hours. After their removal, the vagina shovtld be douched with hot water, and again before rein- sertion of the tami^on. If the disease does not seem to yield, thorou'^h curetting had better be repeated, and in the intervals, when dilating the os, the endometrium may be lightly touched over with a twenty five per cent, solution of ichthyol, or with stronger preparations, if thought advisable, such as tincture of iodine, carbolic acid, or a twenty five per cent, solution of chloride of zinc. Success in treatment will largely di^pend upon a removal of the conditions which cause and perpetuate the disease. Retroversion, retroflexion, and prolapse of the uterus may need correction. Inflammation of the cervix, ovaries, or of the tissues surrounding the uterus should be treated. DISEASES OF THE UTEKUS—METRITIS. 235 Special cnre slioukl bo tnken at each monstrual poriod; a few (lays spe^iit in binl will often do much to check monor- rhagia or dysmenorrhcea, should one or the other bo present. Throughout the whole intermenstrual jjoriod the mode of living should be one of extreme (luietudo, both mental and physical. CHRONIC METRITIS. To this condition the synonyms chronic parenchy- matous metritis; (ircolar luipcrpldsid; and suhinrolntion and sclerosis have been applied. Etiologi/. Chronic metritis may result from three entirely different pathological states: — First, from inter- ference, from any cause, with retrograde metamorphosis of the puerperal uterus after abortion or labor at term, such as puerperal metritis, retained secundines, septic innoculation, laceration of the cervix, over-exertion after confinement, or suppression of milk. Acute diseases occurring during the period of involution have a similar effect. Second, from congestion long kept up by mechan- ical causes, such as displacements, pelvic tumors, and chronic diseases of the pelvic or abdominal viscera; or from congestion indirectly produced by sedentary habits com- bined with constipation, by laborious occupations kept up during the menstrual period, or by long standing cardiac disease. Thirdly, from a formative irritation, or a state of hypernutrition excited by endometritis. Pdtholoiii/. After joarturition the muscular fibres undergo fatty degeneration, by which the organ rapidly dimiidshes in size, so that, at the end of the eighth week, the uterus will have returned to its normal state. Untoward influences may retard or check this process, and the uterus will accordingly remain large, fiabby, and softer than natural. As a result there is hypont'mia, serous infiltra- tion, and a large increase of embrj'^onic elements. Later an increase of adult connective tissue between the bundles 236 MEDICAL AND SURGICAL GYNiECOLOGY. of muscular fibres arises, wliich in time compresses the blood vessels, and leads to uterine aujemia with atrophy of the muscular tissues. The uterus becomes harder than natural, and remains for a long time enlarged, but in time begins to diminish in size as a result of contraction of the connective tissue, and in a few cases becomes smaller than normal. During each menstrual period the uterus, being to some extent an erectile organ, is enlarged and distended with blood. If from some cause it does not return to its normal intermenstrual quiescent state, chronic congestion with hypergenesis of its tissues will follow, and, as a result, the organ will increase in size month after month, until the circulation becomes finally constricted, and in a hardened state the uterus will remain enlarged until after the menopause. Displacements of the uterus at first result in passive congestion. Fibroids keep up constant nervous irritation that induces hyperemia. Cardiac disease and abdominal tumors interfere with the return of blood through the vena cava and jjroduce blood stasis, any of which, when continued for a length of time, will induce hypergenesis of connective tissue in the uterine walls. Course and termination. The length of time which the condition may last is very uncertain. After the connective tissue has once become thoroughly affected it rarely returns to its original condition. The extent of the enlargement of the cervix, the result of areolar hyperplasia, is sometimes very great, equaling in size, at times, a small orange. Sifniptoms. After labor or abortion, the first symi^tom may be a return of the discharge soon after the patient gets up, or the menses may return abundantly in three or four months, while the child is still nursing, or there may be complete menorrhagia. It is not to be forgotten, though, that some women menstruate regularly throughout DISEASES OP THE UTERUS — METRITIS. 237 the whole period of lactation. In all cases, after the disease has been well established, there will be a dull dragging pain through the pelvis, much increased by locomotion; pain on defecation or coition; and painful menstruation, commencing several days before the flow appears and lasting during the whole period. There is often noticed pain in the inammce before and during men- struation; darkening of the areolre of the breasts, if lactation is not present; nervous disturbances; and rectal and vesical tenesmus. As felt bimanually the uterus, in the earlier stage of subinvolution, is enlarged, but more in its long diameter than in its transverse; is slightly softened, somewhat tender, and probably situated low down in the pelvis. The cervix is more or less enlarged and softer than normal. The os is purplish in color, and firm, unless cervical endometritis is present. In cases of long standing, the uterine tenderness diminishes, the walls become hard, the cervix paler in color, and, as sclerosis supervenes, the body becomes somewhat flattened. It might be mistaken for pregnancy in the early stages, but the early symptoms of that condition are entirely wanting. Treatincnt. The sooner treatment is adopted the better, before the stage of induration is accomplished. Cases discovered a few weeks after delivery or abortion should be again put to bed and perfect quietude insisted upon. Any causes which may have been etiological factors, such as retroversion or retained secundines, should be removed. Hot vaginal douches three times a day are decidedly beneficial. Internally, fluid extract of ergot given alone, in half dram doses, three times a day, or combined with fluid extract of hydrastis, in ten drop doses, will have a decided elt'ect in promoting involution. Two or three drams of blood may be removed from the cervix by scarification, three times a week, and a tampon saturated with boro-glyceride placed against the cervix and allowed to remain for twelve hours. 238 MEDICAL AND SURGICAL GYNiECOLOGY. In the enrly stages of menstrual subinvolution, uterine displncement, or other onuses which keep up the menstrual congestion, should be corrected. During each menstrual period perfect quiet, with rest in bed, should be enjoined. During the stage of infiltration both forms yieUl readily to treatment. The appropriate measures to be adopted for such are cleansing the uterine cavity, removing exuberant and diseased tissue^ and checking its reproduction by airect applications, aided by enforced deple- tion and efficient draJnage — the methods for which are identicf 1 with that already enunciated in conjunction with the t 1 / / ' / treatment of endometritis. The appli- cation, twice a week, of fifty to sixty milliamperes of the galvanic current, with the negative poh^ intra-uterine, Fig. 72 — Amputation of the cervix with ilouhle flaps. W, sectional view, showing lines of incision for formation of ttapa and method of suture ; B, front view of cervix, operation complete. will soften the uterus and promote absorption. Pelvic massage will also stimulate the circulation and promote absorption. Operative interference is often of much advantage for the purpose of removing redundant tissue, and to alter the circulation and the nutrition of the uterus. If the cervix is lacerated, trachelorrhaphy should be performed. Where there is decided circumferential enlargement of the cervix and the canal dilated, a wedge-shaped piece may bo cut out of one or both sides, and the surfaces DISEASES OF THE UTERUS— ACQUIRED ATRESIA. 239 brought togotlior ns in trncholorrlmpliy. When this tnilnrgoment takes the shnpo of an elongation as well as thickening, amputation should be i)erformed. Schfoedei'^s met hod for ampntdtion of the cervix. By means of lateral incisions convert the cervix into anterior and posterior lips; next remove the anterior lip by two transverse incisions — one on the vaginal and the other on the cervical side— by cutting upwards towards the supra- vaginal portion of the cervix until the incisions meet each other high up in the cervical tissue. The two flaps thus formed are stitched together. A similar operation is next performed on the posterior lip. CHAPTER XXII. DISEASES OF THE UTERUS CONTINUED. ACQUIRED ATRESIA. STENOSIS. HYPERTROPHY. Besides the result of a congenital defect, the uterus may become closed later in life, producing a condition know as (lequired (dresid. This condition may bo brought about by adhesions forming after child-birth or abortion, or by cauterization with strong caustics or the actual cautery. Sometimes it is simply due to old age, especially when the patient suffers from prolapse. As a result of acquired closure, there may be hematometra or pyometra; the treatment for which consists in overcoming the atresia by puncture, and subsequent evacuation of tlie contents of the uterus, after the manner previously described. Stenosis of the cervix is an abnormal narrowing occurring in some part of the cervical canal. It is most common at the exti^rnal os, wlu^re the opening may be found so small as not to admit the finest uterine sound (pin-hole os). Less frequently it is found at the internal OS, while sometimes the whole cervical canal is involved 240 MEDICAL AND SURGICAL GYNECOLOGY. in the stonosis. In acquired stenosis the prominent symptom is obstructive dysmenorrhcxia, produced by the difficulty whicli the menstrual flow meets with in passing through the cervix. If not relieved it may give rise to chronic endometritis and chronic metritis. Ti'catment. At one time all sorts of metrotomes and scissors, for the purpose of overcoming the obstruction, were in use, but these have now been abandoned as unnecessary. With tht^ patient under an anjesthetic, the cervical canal is entered by means of a fine dilator (Hanks') and the process of dilatation proceeded with. When sufficiently dilated, a glass or hard rubber stem pessary is inserted into the cervical canal and retained there for two or three months. Hypertrophy of the uterus. An increased size of the uterus is commonly due to subinvolution or chronic metritis, but it may be also due to simple hypertrophy, independent of inflammatory action. General hypertrophy is a very exceptional condition, the cervix being the part usually affected. Hypertrophy of the oervix is divided into infra-vaginal and supra-vaginal. I)}fr(t-r:<((ji)i(d luj'pcrtropliii consists in an increase in the size of the vaginal portion of the uterus. If congenital, the enlargement takes place chiefly or exclusively from above downwards, resulting in an elongated cervix. If acquired, the cervix is not only elongated, but thickened, and is frequently thicker near the end than at the base. Treatment. Slight degrees of elongation may be suc- cessfully treated by dilatation, which enlarges the os and shortens the canal. If it is more extensive, amputation of the cervix may be called for. Snpra-Vdfiindl lii/pertrophy consists in the increase, especially elongation, of that portion of the cervix situated above the utero-vaginal junction. This condition is due to prolapse of the vagina, while the body of the uterus DISEASES OP THE UTERUS— DISPLACEMENTS. 241 romnins in plnco, tho prolapsod vn^iiin pulling down tho oorvix nnd thus olongnting it. The symptoms nri'^ thoso of prolfqjso of tho vngiim, with perhaps tho npponranco of ft hyportrophiod corvix at tho vulva. Trratmcnt. In the lesser degrees the uterus may be pushed up, and the cervix supported by a cup-shaped pessary attached to an abdominal .belt. In more serious conditions recourse must be had to operation. Simple amputation of the cervix may be sufficient; if not, recourse may be had to supra-vaginal amputation of the cervix, an operation is reality similar to amputation of the cervix already described, only the incisions are made higher up. Schroedcr^s mcihod for siqird-raf/iiuil (imputation. An incision is made through the mucous membrane at the utero-vaginal junction, and the cervix separated carefully all around, for some distance up. A ligature is passed on each side, around the uterine arteries, to control them, as in the operation for vaginal hysterectomy. The anterior vaginal wall is next cut through, and the anterior vaginal mucous membrane stitched to the mucous membrane of the cervical canal. The posterior wall is next severed and the posterior vaginal mucous membrane stitched in a similar way, thus uniting the mucous membrane of the cervical canal all around to the vaginal wall. Hc<j(ir''s operation differs from Schroeder's in that tho excised piece forms a cone, tho length of which may bo an inch to an inch and a half above the utero-vaginal junction. CHAPTP]R XXIII. DISEASES OF THE UTERUS CONTINUED. DISPLACEMENTS. Even in perfectly normal conditions the uterus is liable to vary greatly in its relations to the pelvic cavity in which it lies. These relations are modified by its own 242 MEDICAL AND SURGICAL GYNECOLOGY. functioiml nctivitieH, as woll ns by tlu^ distontioTi niul ovacuation of the adjacent viscera. With this wido range of physiological mobility, it is kept in place by the surrounding connective tissue, by folds of peritoneum as it is reflected over its walls, and by special ligaments, all of which have alreatly been described in an earlier chapter. When it fails to retain its eciuilibrium, either by excessive movement beyond its normal rangt*, or by losing the power to recover its normal relations, its displacement becomes pathological. Cldstiijicdfioii. Five kinds of displacements are recog- nized: — Version, or displacement involving a change in the axis of the uterus. Flexion, or deformity involving an increase or alteration in the normal slight anterior curve of the uterine axis. Prolapse, or displacement of the uterus in the axis of the pelvic outlet. Torsion, or twisting of the uterus on its long axis. Inversion, or sinking of the upper part of the uterus into its own cavity, or com- pletely down through its canal, into tlie vagina. ANTEVERSION. The uterus is said to be anteverted when its position is so changed from the normal one that the fundus apiJroaches the symphysis pubis, and the cervix points towards the upper portion of the sacrum. The cause of anteversion of the iiterus is usually an increased weight of the organ, produced by subinvolution, hypertrophy, fibroid tumors of the anterior wall — conditions generally accompanied by relaxation of the ligaments and supports, which permit the anteverted uterus to sink down into the cavity of the pelvis. Symptoms. From pressure of the uterus upon the bladder, there will be frequent desire to urinate. In the erect position, there will be a bearing down sensation, and on attempting to walk, an uncomfortable dragging feeling. By digital examination, the body and fundus of the uterus DISEASES OF THE I'TEKUS- DISPLACEMENTS. 248 9 I will bo found close to the sytni)hyHiH pubiB, touching it, or (^ven bolow it, nnd tlui cervix pointinjjf towards the middle or upper portion of the sncrnl excnvntiou. Trcatnioif. As in mnny cnses the displncements depend upon subinvolution or iiyperphisin, the first attempts at treatment must be for the restoration of the organ to its normal size, after which it will likely return to its normal position without further interference. It would be useless to attempt the introduction of any instrument for the mechanical support of the organ, without such previous treatment, and, as the symptoms are genc^rally relieved after the condition which produced them /'' has been overcome, the large number of pessaries once found in the instrument shops have now disappeared, as being wholly un- necessary in the treatment of this deformity. There is one pessary, Grehrung's, which is still held in favor for anteversion. It is double- horseshoe shaped, and is inserted bj' slipping it sideways into the vagina, and then turned so that both bars rest between the sym- physis pubis and the anterior aspect of the uterus. Operative measures of various kinds, such as fixation of the cervix to thvi anter'or wall of the vagina, and shorten- ing of the anterior vaginal wall, have been proposed and carried out, but they have not been received with much favor. ANTEFLEXION. Anteflexion is an exaggeration of the normal anterior curve of the uterus. The body of the uterus may be bent down upon the cervix, or the cervix may be bent upwards towards the body. Fk;. 73. -CJehruiig's pessary. 244 MEDICAL AND SUROICAL OYN,EC()L()GY. (htU)iCH. (■(ni<i<'nif((l. In oarly lif(5 tlio normal aiito- floxioii of tli(^ utcTUH i8 very pronounced. Ah puberty approaohoH, tho body of tho organ dc^vt'lops very decidedly, and tends to become more erect. In Homo, however, as puberty approacheH, such erection of the organ fails to occur, and antefioxion is tlu^ result Failure of the genital organs to dtwelop synimetrically, or as fast as the pelvis <l'.'veiops, favors the formation of autetlexion. The short sacro-uterine ligaments draw the upper portion of the cervix backward, while the short, ill-developed vagina holds the lower end of the cervix forward, as in tho normal condition in young children. The cervix is thus bent forward into the vaginal axis and, accordingly, is apt to be elongated, conical, and with stenosis of the os, while the ill-developed fundus is forced over the bladder by downward pressure. Changes in the uterus. Inflammatory changes in the uterine walls, or their relaxation, or atrophy of tho tissues at the internal os, favor exaggerations of the normal anteflexion. ClKDKjes in the liyaments. Shortening of the sacro- uterine ligaments may take place from contraction follow- ing parametritis posterior, or from peritoneal inflammation about them. When such occurs the ligaments drag the upper i)art of the cervix toward the hollow of the sacrum, while the body of tho uterus becomes bent in an exagger- ated degree by the superincumbent structures. Sifjnijicance. In unmarried and sterile women ante- flexion is by far the most common form of displacement. The views held concerning this condition have of late been changed materially, and the exaggerated ideas once held of the cliiiical importance of anteflexion have been almost entirely abandoned. Recent investigations have shown that, in minor degrees, antofloxions are practically of no importance, neither causing pain nor preventing conception; and when of a more marked character they DISEASES OP THE UTEUU8 — DISPLACEMENTS. 215 produce only two possible' hnd results, imniely, dysmeiior- rlnvn mid sti^rility. Si/inpfoniH. As 1ms been explaiiu'd, tlit* symptoms nro not very marked. Aside f n m dysmenorrluim and sterility, ftii uiioomi)li(;nted fiexioti produces no symptoms. CVr- tnin complications mny. however, be present, which, even in tlie minor degrees of tlexion, may produce symptoms such as chronic catarrh of the uterine mucous membrane and spasmodic contraction of the circular fibres at the internal os. The first may produce congestive dysmeuorrhom; the second the obstructive or neuralgic variety. Digital examination will tind the cervix well back in the pelvis, and pointing forward almost in the axis of tlu^ vagina. Tlu^ angle of flexion can easily be felt, the cervix lying under, and the body of the uterus over, the finger. By bimanual and rectal examination, it is possible to determine the condition of the ligaments and the extent of adhesions, if any. The sound often gives material help in determining the exact position of the fundus, and to facilitate its introduction, it may have to be bent pretty sharply towards the point. There is a condition known as anteflexion with retroversion, in which, from child- birth, debility, or other causes, the uterine ligaments have become relaxed, and allow retroversion to take place after flexion has become permanent. In such cases the ante- flexed uterus falls into retroversion in Douglas' cul-de-sac. Treatment. The minor degrees of anteflexion require no treatment. Catarrh of the endometrium, engorgement of the uterus, congestion of the ov ries and tubes, if present, should be treated on accepted principles. Para- metritis posterior, and adhesions from recent peritoneal inflammation, are benefitted by vaginal tampons. To overcome the two ijrominent symptoms, dysmenorrhcwa and sterility, stenosis of the os nust be overcome, the flexion straightened, and the canal kept open. This can best be done by dilatation of the cervix, under an 246 MEDICAL AND SURGICAL GYN/ECOLOGY. nric'cstluitio, niul if no inflnmmntory condition exists to contrnindicuti' it, by the HnbHixj^ucnt introduction of a glass stem pessary, to be worn for two or thro(^ nonths. It may be held in position for the first few days by a gauzt> taniijon, and subsequently by a Thomas cup pessary. If, from satisfactory reasons, it is deemed advisable to intro- duce the glass stem, repeated dilatation with Hanks', or other small dilators, may be employed at the home of the patient. In old cases, with well pronounced endom- etritis, accompanied by rigidity of the uterus and dys- menorrluiea, thorough dilatation of th*? cervix, curettage and cauterization of the endometrium should be first performed. The use of pessaries of any kind whatever have been abandoned, the best results b(ung obtained from mechanical treatment. Should impregnation occur, a complete cure may with certainty be promised. RETROVERSION AND RETROFLEXION. The uterus is said to be retroverted when the body of the organ is turned backward. According to the degree to which the tilting is carried, the os points downward, or forward against the symphysis, and the fundus turns upward, or backward towards the sarrura. Retroi'u .Tion is that displacement in which the body of the uterus is bent backward, the cervix remaining in its normal position. As in most cases of retroflexion some degree of retro- version is present, the os will change its direction also, and in well marked cases, the fundus will be found lying in the lowest part of Douglas" pouch, and the os looking toward the lower margin of the symphysis. Causes. When the utero-sacral ligaments are relaxed, the cervix is liable to be carried too far forward, and the fundus is then likely to fall backward. When the round ligaments are relaxed and fail in their function of keepiirg the fundus directed forward, retroversion is favored. Along with changes in these ligaments, there is apt to be DISEASES OF THE ITERUS— DISPLACEMENTS. 247 rclnxntion of the broad ligaments, and of tho structures whicli enter into the formation of the floor of the pelvis, the result of over-distention, subinvolution, or laceration. If the bladder and rectum are proialJS(^d to some extent, as they are apt to be under such circumstances, the subinvoluted uterus, having lost much of its support, descends somewhat into the pelvis, and a backward tilting of its bo( V is the inevitable result. Changes in the uterus, causing in- duration of the uterine tissue, and destruction of its normal flexibility, such as that pro- duced by subinvo- lution, chronic me- tritis, and tumors in the walls, render that organ liable to be affected by the influences that press the fundus back- wards, and it will thus suffer retroversion. It may occur as a result of a strain, or fall, or other jar to the body, especially if the accident occurred at a time when the fundus was tilted backward by a distended bladder, and, remaining in that iiosition, is pressed into a persistent state of retroversion or retroflexion by the superincumbent pressure. Habitual over-distention of the bladder will keep the fundus directed towards the promontory of the sacrum, and a permanent retroversion will thus be acquired. A permanent backward displacement is, in some cases, the result of peritonitis leading to adhesions that bind the posterior surfaces of the uterus to the Fig. 74. — Anteflexion with -etroposition. 248 MEDKJAL AND SURGICAL GYNECOLOGY. rectum nnd to the posterior wall of the pelvis. Backward displacements may arise from congenital defects, or from subsequent want of symn'etrical development between the pelvis and genital organs. Congenital shortening of the sacro-uterine ligaments, combined with retarded develop- ment of the vagina, will draw the cervix forward, and hold the fundus backward. Sijmpfoms. Of all the displacements, retroversion and retroflexion are the most common. When the displace- ment has persisted for some time, the patient will complain of a bearing down or sinking sensation in the pelvis during standing or walking; and pain in the lower I)art of the sacrum and coccyx, perhaps extending down the back of the thighs along the course of the sciatic nerves. Sterility, leucorrhoea and profuse menstruation are often prominent symptoms. If the ovaries are pro- lapsed, the pain will be more acute. The function of the rectum may be disturbed, preventing an easy escape of its contents, or causing frequent desire for defecation, accom- paaied by mucous dejections. Reflex symptoms are often present, characterized by hemicrania, frontal and occipital headache, intercostal neuralgia, gastralgia, nausea and vomiting, or there may be a general depressed nervous condition. The examining finger will find the body of the uterus horizontal, or tijiped backward, more or less, into the excavation of the sacrum, with the cervix pointing upward, toward the anterior wall of the vagina, in retro- version; or in the axis of the vagina, with an angle at the junction of the cervix and body, in retroflexion. Bimanual palpation will show the body absent from its natural position, and the use of the probe will indicate the direction of the uterine canal. If the ovaries and tubes are prolapsed, they will be found lying on either side, or immediately behind the body of the uterus. TreatmoHt. The treatment consists in the restoration of the displaced organ to its normal position, and its DISEASES OF THE UTERUS — DISPLACEMENTS. 249 rotontiou there. Elevation of the retro-displaced uterus may be aeeoinplished by the fingers, posture, and instru- ments. The usual method is to put the patient in Sims' position, insert the index and middle fingers of the right hand into the vagina, and press the body upward, nhvr which the index fiugin* is passed in front of the cervix and pushes that part backwards, while the middle finger remains in tlu^ posterior pouch. If this method fails, particularly wlu^n the case is one of impaction, the patient may be put in the genu-pectoral position, and. after admitting air into the vagina by means of a Sims' speculum, efforts are made, by the aid of a depressor or cotton on a holder introduced into the riictum, to dislodge the fundus from the sacral excavation. If these manual and postural methods fail, the reposition may be attempted, with the patient in the dorsal or Sims" position, by means of a large blunt sound or Sims' or Emmet's repositor. The uterus having been replaced, it should at once be retained in its normal position by a properly fitting support, or. if considered inadvisable to use such, by tampons, or gauze packing inserted behind the uterus. It may not be possible to (completely restore the uterus at the first attempt, in which case the attemi^ts are to be repeated at suitable intervals, the advantage gained at each attempt being kept up by the insertion of tampons. Pessaries. There is mujh diversity of opinion on the use of pessaries generally, but, notwithstanding the pro- gress made in treatment of displacements through surgical aid, pessaries seem to be, to some extent, a necessary evil. As has already been stated, in anterior displacements pessaries are but little used; and in prolapse, especially when there is (h'scent of the vaginal walls, it has been shown, when speaking of rectocele and cystocele, that they cannot be well retained, and hence ari^ of little or no benefit. In retrofiexion tlu'y are still found to be of much UBe, but to obtain beneficial results, two indispensable 250 MEDICAL AND SURGICAL GYN/ECOLOGY. conditions miiHt bo observed:— First, that the uterus sliould bi' returned to its norinfil position; second, tlint the pessary should bo properly fitted, and should, without injury or discomfort to tho wearer, retain the uterus in its normal position. Varieties. The cardinal principle upon which most pessaries for retro-displacements are constructed is that of leverage, first introduced by Dr. Hodge. It acts on the principle of the pushing down of a short anterior lever, and the consociuent Fig. 7s-Hodge pessary, tilting upward of a loiig postorior lever, and all pessaries for rotro-displatiomonts, with few excep- tions, are based on this idea. The instrument devised by Hodge is of equal width at both extremities, and with two curves. Albert Smith modified this form by narrowing and pointing the lower extremity, in order to enable it to rest upon the symphysis — an innovation which has proved Fi<;. 76— Allien Smith Pess.nry. Fig. 77 — Thom.as' retroflexion pessary. a permanent one — and nearly all pessaries are constructed after that plan. According to the length and width of tho vagina, the depth and width of the postorior vaginal pouch, the firmness or relaxation of the postorior vaginal wall and ijorineum, the pessary will have to be broader, longer, or more or less curved. If there is retroflexion, with considerable relaxation of the posterior vaginal wall and uterine ligaments, a pessary with a sharp postorior curve will usually be required. For this form of displace- ment Dr. Thomas has added a bulbous enlargement on DISEASES OF THE UTERUS— DISPLACEMENTS. 251 the posterior crossbar, wlioreby the body of the uterus is prevented from tipping mid biuidiiig backwards. C()iifr<i-{nilic(ifi(nis. All imrnovabhi, iioii-replaceabie uterus is always an absolute contra-indication to the use of a pessary, whethc^r the cause be recent or remote. So also is the presence of fibroid or ovarian tumors. Tm^crtion. The patient being placed on the back- some prefer Sims' position — a suitable pessary is selected, and smeared with some unguent. The anterior cross-bar is taken between the index finger and thumb of the right hand, and the pessary held vertically, while the index finger of the left hand is made to draw back the perineum. The pessary is now passed between the vulva, through the introitus vagiiue, and, as it is about to impinge ; 'jon the cervix, the index finger retaining th(^ perineum is passed inward, and catching the posterior bar. draws it downward and backward under the os. The right hand continues to push the pessary onward, and at the same time rotates it from the vertical to the horizontal position. 'The anterior bar must then be depressed downward and backward to settle the pessary in its place, and while so doing the left finger should make sure tliat the cervix is in its proper place. A pessary properly fitted should produce neither pain nor discomfort, but sometimes, after it has been worn for a few months, abrasions are formed by pressure, and tlu>y may even become imbedded -n the vaginal walls. In this way urinary and rectal fistulje have been formed. After introduction, it is well to allow the patient to walk about, to make certain that it gives no discomfort, aftc^r which she should be re-examined to ascertain that the pessary remains in position. The patient should be advised to take a tepid vaginal douche every day and to return from time to tim(> for i-xamination. When tlu^ fundus and body of the uterus are adherent from inflammatory adhesions, or cicatricial contractions, 252 MEI>1C!AL AND SURGICAL GYNAECOLOGY. attempts to roplncci the ori^nn will usunlly fail, and an effort must then be nmdv to softi^n and gradually detach or stretch tluMU. This may be done by careful bimanual and rectal rnaiiiijulation, by uterine massage, and by vaginal pa(^king with tampons or gauze, with the patient in the genu-pectoral position. Opcrativr treatment. When a pessary fails to cure the displacement, or when the uterus cannot be held in place, an operation may be performed to accomplish this purpose. Extra-peritoneal shortening of the round ligaments. Ale. r (UK lev'' s oiienitlon. This consists in making an incision over the external inguinal ring on each side, dissecting out, picking up, and drawing out the round ligaments, until the fundus points towards tlie anterior abdominal wall. Tlie ligaments are then ma(h^ fast in the wound by buried sutures, which pass through the pillars of the ring and th(^ ligament, after which the redundant part is cut off, and the external wound closed. Intra-peritoneal shortening of the round ligaments. Wi/lie''s method. After opening up the abdominal cavity, the round ligaments are brought into view and denuded on their inner surfaces. Each round ligament is then doubled on itself, and the loop retained in position by the introduction of ligatures, after which the abdominal wound is closed. Vaginal fixation. Vaginal hysteropexy. With the patient in the dorsal position, and an Edebohls" speculum inserted, a median incision is made in the anterior vaginal wall, from the neck of the bladder to the cervix, after which the bladder is carefully separated from the uterus and vagina as far as the peritoneal reflection. The anterior surface of the replaced uterus if; drawn freely forward by means of bullet forceps, and stitclied to the incision in the anterior vaginal wall. This operation hau now been practically abandoned. DISEASES OF THE L'TERUS — DISPLACEMENTS. 253 Ventral fixation. Abdominal hysteropexy. Tliif* mc^thod consiKts in opc^niug tlic nbdoiuiiml cnvity. nnd suturing the body of the uterus to th(3 nnterior abdomiuul wnli. This operntiou has^ proved very satisfactory, both as to its performance and results, and the only serious objection which can be raised to it is the influence which it will have on pregnancy and labor. From care- fully prepan (1 statistics, it has been shown that women subjected to this operation are less apt than others to become pregnant; that pregnancy and labor are, as a rule, uncomplicated. Inertia uteri is, however, not infrequently met with, and serious or insuperable objections to labor may be produced if the fundus and nnterior wall of the uterus are imprisoned below the point of attachment between the uterus and abdominal wall. Various methods have been (U^vised for introduction of the sutures, to avoid difficulties arising during pregiumcy and labor. Kcllij',^ method consists in suturing the uterus at th(3 junction of the fundus and posterior wall, to the abdominal wall, with buried silk sutures. In this techniqu"^ the sutures which suspend tho uterus embrace only the peritoneal coat of the abdominal wall, and are introduced superficially through the uterus. OUhlumaen sews the cornua to the abdominal wall by means of silk- wo m gut buried at the aponeurosis, the anterior rather than the posterior surface of the fuiulus being included in the sutures. Leopold uses silk sutures passed through the entire thickni'ss of the abdominal wall, one at each cornu, and tlu^ third between them. The sutures are passed through the anterior rather than the posterior surface of the fundus, and to ensure firm attachment the peritoneum of the fundus is scraped oft*. Aft(^r fixation the abdominal wound is closed in the usual way. Latero-versions and latero-flexions are cuther con- genital or acquired. In either case they occur through shortening of the broad ligament on the side towards 254 MEDICAL AND SURGICAL OYNJICOLOGY. which the body tips. The only renl importance of theso displncomonts, particularly floxions, is the production of sterility. The diagnosis can be readily mad(> by bimanual examination and by the sound. No treatment, unless that of persistent taniponading of the vagina to stretch the contracted ligament, offers any reasonable chance for success. PROLAPSUS. Prolapsus is a displacement of the uterus in tlie axis of the pelvic outlet. Three degrees liavo been described. In the first degree there is simple ilescent in the axis of the pelvic outlet, the cervix touches the tloor of the pelvis, Fig. 78. — Procidentia uteri. the fundus is pi oportionately below its normal level, and the uterine axis slightly inclined backwards. Neither the bladder, rectum, nor the vagina is necessarily involved. In the second degree, the external os approaches the vaginal orifice, the body of the uterus is retroverted and lies in the sacral excavation, and usually the anterior vaginal wall, together with the posterior wall of the bladder, accompanies, if it does not precede the prolapse. In the third degree, the cervix protrudes from the vulva riSEASliS OF THE I'TEKUS — IJISFLACEMENT.S. 255 moro or loss (i)r<)('i<l<'uti(i), evoii to tlio extent of the ciitiro extrusion of the uterus. The anterior vnginal wftll and posterior wall of the bladder, down to the meatus urinarius, protrude from the pelvic cavity, and in a very large proportion of cases the posterior vaginal wall and the anterior wall of the rectum are prolapsed to the same extent. Causes. Of the indirect causes, laceration, over- distention, or subinvolution of the perineum after parturition is the prime element in the weakening of the pelvic floor that eventuates in displacements of the jjelvic contents. Varying conditions of the vaginal walls arising from over distention or lack of tonicity, and relaxation of the ligaments persisting for some time after parturition, increase as well as facilitate the tendency to descent. Absorption of adipose tissue, such as that which occurs in those suffering from wasting disease, also lessens the natural support and renders its desc«Mit more easy. Among the conditions which operate more dirt^ctly may be mentioned enlargement of the uterus. If. after partu- rition involution is not complete, or if the organ is hypor- trophied as a result of chronic metritis, or enlarged from development of neoplasms in its walls, the increase in its weight, favored by some of the indirect causes mentioned, is almost certain to end in prolapse. One of the most common causes is frequent parturition. A large majority of cases of prolapse occur in women who, after one or more severe child-births, are unable to remain at rest for a sufficient l(Migtli of time to allow the pelvic organs to regain their normal tone. (Jomplicafio)is. In extreme cases, not only has the uterus descended, but the bladder and rectum will b(^ found displaced, and the ovaries will have descended into the pelvic cavity to the depth of Douglas' pouch. In its descent a chronic metritis may take place, by which the walls are thickened and indurated, and the endometrium 256 MEDICAL AND SURGICAL OYNJICOLOGY. oxpaiidod ftiul vnscular. Ouo of tlui most comiiK m oom- plicintioiiH is Incorntioii niid ovorsion of the lips of tlui cervix, and often accompanied by a lacerated perineum. Hypertrophy of the cervix in also a common occurrence, in consequence of the irritation produced by the laceration. When prolapse is compU>t(i the vaginal walls b(>come smooth, dry, and are deprived of their rugosities, and in cases of long standing the epithelium in places takes on the appearance of the epidermis. Imperfect evacuation of the distended bladder leads eventually to cystitis, and the rectum may be the seat of irritation and of undue accumulation of fecal matter. Sijtnptoiiis. In cases which develop gratlually tlu^n; may be no decided symptoms at first, but .soon ba(!ka(^ho and a bearing down, dragging sensation about the vulva, with a disagreeable feeling of weakness or want of support, is noticeable. Difficult urijiation and defecation, find even the symptoms of cystitis, are often prominent. The diagnosis of prolapse of the uterus is excteedingly easy. The examining finger will readily determine that the cervix is lower in the pelvic cavity than it should be, or that it is protruding through the vulva. Bimanual exam- ination will indicate that the fundus is absent from its normal position, and eitluT retroverted, or low down, at or near the pelvic outlet. Accompanying prolapse in th(« second degree will be found cystocele, and in the third degree both cystocele and rectocelo. Tri'dtmcnt. The treatment of prolapse is either palli- ative or radical. Minor degrees of recent origin may be treated by astringent injections and by tampons inserted into the vagina in the genu-pectoral position, and later by the ins(>rtion of a retroversion pessary. In the more advanced degrees of prolapse, mechanical and palliative means will be found of doubtful benefit, but treatment by means of them may be made when operations are inad- missable. A large soft rubber ring, or pessaries inflated DISEASES OF THE I'TEKUS - DISPLACEMENTS. 257 w'ifli Jiir, or mado of (Onstifi \vir(\ will sonu'timos rctniii i\ui uterus ill tlu^ p(>lvis by (listciidiuj^ i\\v uppcT part of tlii^ vagina. In most cases of (Hinipli'tc prolapst', it is necessary to use n supporter composed of a c,v\ and stem pressing against the vaginal portion of tlu> uterus and fastened billow to an abdominal belt. The wearing of it is, however, often very annoying and fre([Uontly causes excoriations and ulcerations. ()j)('i'(ifir(' fi-c(if)iiciil. This consists in applying m(>thods for the diminution of the size of th(^ uterus, for restoring the tone of the utt>rine ligaments, and for the repair of the uterine supports. Tliese may be accomplished by amputation of the cervix if it is much hypertrophied; by repair of a laceration in it; and by thorough curettage; all of which can b(^ completed at one sitting, aftl^r whicrh the liganuuits will probably regain their tonicity. The round ligaments may be made at once to renitw their support by Alexander's operation for shortening them, already describ(>d. INVERSION OF THE UTERUS. By inversion is meapt a more or loss complete turn- ing inside out of the body of the uterus. There may be simply a folding in of tlu^ fundus, or a projection of the fundus through the dilated cervix, or a complete inversion of both uterus and cervix. Inversion comes under observation at three different periods: Immediately after the occurrence of the accident, or that form appearing during or immediately after child- birth; second, about six weeks after labor; and third, that which occurs after a lengthened period, often many years. Leaving out the first form, which belongs more to the subject of obstetrics, two classifications may be made: Inversion (liirhu/ inroinfioiinnd inversion ((ff<'r involnfion. The predisposing causes are, an enlarged uterus and a relaxation or an inability on the part of some portion of 258 MEDICAL AND SUIKHC'AI GYNECOLOGY. Fig. 79— Incomplete Fk;. 80 —Complete inversion of inversion of t\w utcriin' wall to (U)iitnutt, hucIi rh oxists nt tho plno,(4ital Hit(^ nftor labor, or at tlu^ phwv of orij^in of a hohhIK' iiitra- utoriiio tibro-myoma. When hucIi (toiulitioiiH exist, umiHual utorino coutraotioii may tako i>lac(% by which the weaki'iied area is depressed and inverted, and the first sta^e of inversion is initiated. Subsequently a species of peri- staltic movement, proceeding from above downwards, is set up in the uterine muscular coats, until inversion becomes nion^ or less complete. Sijnipfomn. The chief symp- tom for which n patient pre- sents herself, is repeated hem- orrhage, which may already have undermined the constitution by its frequent recur- rence or profuseness. To this symptom are added leucor- rh(ua, dragging pains, and diffiv ulty in walking. Physical examination will reveal tlu^ peculiar condition present. When involution has not taken jilace, or is not complete, the peritoneal cup formed by the depressed fundus contains all, or a large portion of the uterine appendages, and may also contain loops of intestine. The inverted uterine body projects into the vagina as a large soft, more or less spongy mass, upon which ran be discovered small depressions corresponding to the orij,in of the Fallopian tubes, and from the surface of which blood seems to slowly ooze. Inversion after invo- lution has neither intestine nor uti^rine appen- dages in the cup. except the ends of the Fallopian tubes and the ovarian ligaments. The inverted body is firm, pear-shaped, and hangs out of the cervix like a fibroid polypus. The mucous Fk;. 8i~I'olvpus simiiKitini; com- plete inversion of uterus. DISEASES OP THE UTERUS — DISPLACEMENTS. 259 nuMnhmiio roH<imbh<H ^ramilntion tissiu*, mid from it lu'inorrhago tnkoH plmus but not to such an ^^\tont as in tlio proviouH form. I)i(((/n<>sin. Prolapse of the uterus and hyiMirtrophy of the cervix might be mistaken for inversion. In tht^ former the os is found in its normal place, through whicli the sound readily enters, and the tumor is broader above than below, the reverse being the case when invc^rsion is present. A fibroid polypus with a h rge pedicle might cause an error in diagnosis. In inversion the uterus is darker and softer than a fibroid, and the sound introduced between the body and cervix discovers no opening into the uterine cavity. A fibroid can be slightly twisted on its long axis without twisting the cervix; in the case of inversion this cannot be done. With a fibroid, biman- ual and rectal examination reveals the fundus of the uterus at, or near its proper place. In inversion there is an abisence of the fundus, and a cup-shaped depression occupies its plac(\ Trcdfmnit. Inversion should, if pos- sible, be reduced as soon as recognised. The methods for reduction are mtmiud, iustrioncntdl, and opcrdtive. Manual. The fingers of one hand, formed so as to make a cone, are inserted into tlie vagina and the tip of the cone pressed against the summit of the inverted uterus, or alternately against one uterine cornu and then the other, while the other hand exerts counter-pressure, or with the fingers attempts to dilate the ring through the abdominal wall. Emmet describes a method of reduction in the follow- ing way : The hand is passed into the vagina, and, with the fingers and thumb encircling the portion of the Ki<i. 83.--Kil)rous [jolypus. 260 MEDICAL AND SURGICAL ftYN/ECOLOGY. body olosi' to tlio st^at o^ inversion, the fundus is allowi^d to rest in tlio palm of the hand. This portion of the body is firmly grasped, pushinl upward, and the fingers immedi- ately separated to tluur utmost; at tlu^ same time the other hand is employed over the abdomen in the attempt to roll out tlu> parts forming the ring, by sliding the abdominal parit^tes over its edge. This manoeuvre is repeated and continued. At length, as the diameter of the uterine cervix and os is increased by lateral dilatation with the outspread fingers, the long diameter of the body of the uterus b( -oLies shortened and tiie degree of inver- sion proportionately lessened. After the body has advanced well v/ithin th'> cervix, steady Qjjward pressure upon the fundus is applied by the tips of all the fingers brought together. Iiistrumciital. Ingenious minds have devised instru- iTients by which a steady pressure can bv effected upon the inverted fundus, while counter- pressure is exercised upon the cervical ring. By the use of i ich instrumenl,s re- position of the organ lins been effected in less than twenty four hours. A more sim])le method consists in packing the vagina witli gar.ze in such a manner that the fundus will be pressed upward, in tlie direction of the axis of the superior s':rait, whih' the dihited wall of the vagina makes traction upon the c(>rvix. Opcvdtivc. Tlie only operative measures for thc^ reduc- tion of the inverted uterus is that proposed and carried oat first by Dr. Tliomas. It (;onsists in opiming tlie abdomiiml cavity, stretching the ring witli a kind of glove stretcher, while the hr..".'' iiitroduced into the vagina forces the fundu,; throu.;h the rii\g. and up into its normal plawi. Should efforts by this method fail, resort nmy be luul at once to hysterectcnny to relit^ve the distressing as well as dangero\is condition. Amputation of the inverted uterus, preferab by the elastic ligature, is aLso recommended v.heT other less radical methods hav^ failed. DISEASES OF THE UTERUS — BEN'IGN NEOPLASMS. 261 CHAPTP]R XXIV. DISEASES OF THE UTERUS CONTINUED. HENKiN NEOPLASMS. Cysts in the cervical canal are of common occur- rence and arc erroneously called ovules (>f Nabotli. Like cipher cysts lined with epithelium, ihey orij^inate from glandular formation, and are thus a species of adenoma. The contents are li([ui(l. semi-li(|uid, or form a jelly-like mass. The tit'atment consists in opening them, and touching the interior with tincture of iodine. Myxoma. Glandular polypus. All so cnlled polypoid tumors of a jelly-likt^ consistency, and half translucent to the naked eye. appear under the microscope to be made up mainly of myxomatous tissue. They are found most fre(piently in the cervix, and are usually sessile at first, but have a tendency to become pedunculated nnd protriulo through the os as bluish or purplish red lobules. The symptoms which usually attract attention are leucorrluna and luunorrhage, and. on examination, a small iumor will, perhaps, be seen i^rotruding through the o.s. The treat- ment consists in removal with the curette if intra-uterine, and in torsion if cervical. FIBROMATA. To those tumors of the uterus which have the .same structure as the uterus itself, the names ol Jihroiud, mi/oma, Jihvoiis fiitHO" find Jihi'oids li::ve been given, and from the fact that tlu^y are generallj^ of the mix(>d variety, com- posed of muscle fibres and fibrous conniM'tivi' tissue, the corresponding terms inj/o-Jihi'oiiKi or Jihro-DiijonKi have been applied. They are usually benign, that is to say. incapable^ of becoming g(>neral and infecting t'u' org.'inism. but they are not .so harmless as the older ...thors con- 262 MI5I)K!AL AND SURGICAL GYNECOLOGY. ;. 83. — Interstitial fibroids. Fit;. 84. — Subserous and su))Miucous fibroid. siderod tliom to be. Tlio knowlwlgo of tlio orijjin of these tumors is still very imperfect. Klobs asserts that they have tlieir origin in n pro- liferation of the connective tissue and muscular layers of certain vessels. Another authority asserts that they ar(> due to a round cell found alonj^ the capillaries, which by growth obliterates them ; the cells then become fusi- form and produce nodules, y The tumor may consist of one mass, or of several dis- tinct masses, developed side by side, and enclosed in a single capsule, or many tumors with individual capsules may be scattered throughout the uterine walls. They vary in size from a tumor the size of a pea to a growth of immense proportions. The majority have their origin in the body of th3 uterus and most often are situated in the posterior wall; least frequently they spring from the cervix. They are classified according to the relation which the tumor bears to the uterine tissues. The iiifcrsfiti'dl develop within the uterine walls, and are surrounded on all sides by iterine muscular tissue. The finh-miic(>ut^ develop imme(\ately o** just below the mucous membrane, and project into the uterine cavity without becoming pendulous <^sv'.s'.s'/A'). The poli/itoid have their origin under the mucous membrane, on the surface of the muscular wall, from which they project more and more, as they grow, until they bec(^me i>endulous. The sKb-pcrifoncdJ or siih-scrous develop upon, or near the external surface, under the peritoneum, and either project upon the suiface, or become pedunculated. DISEASES OF THE I'TEUrS- BENIGN NEOPLASMS. 2{)li Th(i I'litrd-liutnuciiloiis. nn iiuportaiit sub-vuricty, develop in the thickness of the broad ligament. Htrnctun'. To the naked ey(^ thesi' tumors are eoni- posed of dense tissue, shiny, or rosy whit(\ elastic, giving a very clenu surface on section, and, when examined under the microscope, exhibit varying i)roportions of connective tissue and muscle Hbre irregularly intt'rwoven. Their vascular supply is relatively scant, but they are apt to be FiLi. 85 — Large pedunculated fibroid of uterus, i, cervical canal ; 2, 2, ovaries; 3, liliroid ; 4, fundus of uterus, (Krom the pathologic.1l lalxiratory, (Jueen's University.) surrounded by vascular and hypertrophic uterine walls. In tumors of considerable size, large arteries are sometimes found under the peritoneum, or in the capsule, and wIumi such n condition exists the peripheral veins arc> sometimes th(> size of tlu' jugular, and adherent on all sides to the muscular bundU^s which hold them wide ()i)en. WIumi this arrangement is well marked and the tumor hollowed out by vascular lacunu3 due to dilatation of the capillaries, 264 MEDICAL AND SURGICAL UYN/EC(lLOGY. tliere exists what Vircliow calls '• tolcaii,i^i('('tatic myoma." or " myomn caveriiosum,'' the portion degciierated resem- FlG. 86. — Kil)ro-cyslic tumor of uterus. i. Incision in wall of l?.rge cyst, i, a. Interior of cyst. 3. Small cyst. 4. lUerine cavity. 5. Multiple fil ro-myom.T. (>. "undus of uterus. (From the pathological lalioratory, Queen's University.) bliiig a sponge soaked in blood. Polypoid tumors some- times contain large blood vessels, but when removed the DISEASES OF THE UTERUS — BENIGN NEOPLASMS. 265 contractility of tlio walls usunlly brings about rapid hsemostasis. AUerdtioa <ind (legcywrdtion. At the mcniopauso most of the fibromata undergo a progressive induration and diminution in volume, and in such a state often persist without causing any morbid reaction. Very rarely they undergo calcification by a deposition of carbonate of lime. During sexual activity they may undergo changes depen- dent upon physiological processes. During pregnancy a marked increase in size is sometimes noticed, due princi- pally to changes in the circulation causing cedema of the growth. CEdema occurring in tumors existing in a non- pregnant uterus is frequently the forerunner of gangrene. Fatty degeneration is very rare, and where suppuration exists, it is for the most part the outcome of gangrene. Cystic derfeneratiofi is a peculiar process of liquefac- tion characterized by a primary serous infiltration and associated with myxomatous softening of the growth, accompanied by an oedeniatous swelling of the connective tissue, followed by more or less disintegration. When advanced, these changes result in the formation of spaces tilled with linid, the walls of which are formed by the non- disintegrated portion of the tumor. At first the muscular bundles prevent the formation of large cavities, and give to the cyst wall a peculiar uneven appearance, like the columnse of the heart. Subsequently, however, tliese also become disintegrated and large spaces are formed. The contained fluid varies in color, from a pale amber to a dark brown, the changes in color being due to extravasation of blood. The fluid, as a usual thing, coagulates spontaneously, and chemical and microscopic^al examinations show it to contain serum-albumen and fibrin, with more or less mucin, blood, and detritus from degenerated tissue. Etiolo()i). Although much attention has been paid to the causation of these neoplasms it must be admitted that 266 MEDICAL AND SURGICAL GYNAECOLOGY. little or nothing is known. No single cause assigned has been proved with reasonable certainty. H]imptows. Small subserous tumors sometimes exist without causing any .symptoms. Hemorrhage, either monorrhagia or metrorrhagia, is common to nearly all the fibromata. In the polypoid and submucous varieties it is the most noticeable symptom. In the interstitial variety it is less frequent, while in the exclusively subserous it is very often absent. More or less profuse leucorrhoea, and intermittent watery discharges are also present in the majority of patients. A symptom of equal importance is pain, at times of an intermittent character, and most intense during menstruation. It may arise from painful uterine contractions due to the presence of polypoid tumors, or to retention of secretions; from pressure of a polypoid or submucous growth at or near the internal os; or it may be due to pressure upon the surrounding pelvic tissues, or upon the bladder, rectum, or sciatic or gluteal nerves. Pressure on the rectum may cause obstinate constipation; pressure upon the bladder, vesical disturb- ances; and on the ureters, retention of urine in the pelvis of the kidney, with subsequent renal changes. Pregnancy is not infrequent, and should it occur the tumors are apt to grow more rapidly, but after partiirition they may comijletely disappear. Course. Fibromata in most cases run a benign course. They grow slowly and seldom cause death directly. As has been already stated, they often undergo progressive induration and diminution after the menopause. If polypoid thoy may be expelled by the vagina. Multiple, interstitial, or submucou.s tumors may attain a great mzQ, but when a large number start simultaneously, intermediate pressure tends to cut off the blood supply and arrest growth. Submucous and interstitial tumors may become gangrenous, followed by suppuration, and when such a DISEASES OF THE UTERUS — BENIGN NEOPLASMS. 267 course is pursued death may follow from peritonitis, septioasmia, or pyremia. I)i<((/)iosis. Single interstitial, submucous, and poly- poid fibroids, if of moderate size, may be mistaken for pregnancy, retained menses (luematomotra), malignant disease, or subinvolution. A fibroid uterus is harder to the feel than in pregnancy, and the os, although some- times slightly dilated, is not softened or deepened in color, and there is absence of the familiar signs of pregnancy. A large polyjjoid growth often dilates the cervix, and may be felt presenting at the os. In ha^raatometra the retained discharges give the uterine walls a tense elastic or fluctu- ating feel, and, on examination, the internal or external os will be found impermeable, and perhaps the menses will have never appeared. In malignant disease, tlu^ age of the patient will assist in making the diagnosis. The peculiar offensive discharge is characteristic, and if in doubt curetting and examination with the microscope will make the condition clear. Subinvolution generally produces cervical, as well as corporeal enlargement, the body is flatter, the antero- posterior diameter being not so much increased as when fibroids are present. Interstitial multiple tumors cause the uterus to enlarge more or less irregularly, and make the canal to become so tortuous that n probe can with diflficulty be passed, or even not at all. When the tumors are near the outer surface, the probe may enter readily the full length of the canal, but bimanual examination will disclose the hardened projections on the outer surface of the uterus. Retro-uterine hematocele and ha?mHtoma may be differ- entiated by bimanual examination and by tlu> use of the sound. In such cas(^s the uterus will likely be found in front of. or at one side of the tumor, or it may be pushed up behind the pubes, where it can be moved indep«>ndeiitly of the mass. A small subserous tumor, if pedunculated. 268 MEDICAL AND SURGICAL GYNECOLOGY. may bo miHtnkcMi for a diHoasod ovary. Tho formor is usually tinner to the touch than Ih tlu^ ovary, lias a smoother surface, and is not siMxsitive on bimanual pressure, and the pedicle may be palpated. A tumor partially extruded from the os may be mistaken for cancer, especially when the former is gangrenous. In both cases there is profuse vaginal discharge, but witli care tho cervix may be shown to surround the protruding mass. Fibro-myomata of the pelvic variety may resemble pelvic exudations, but if the tumors are not adherent they can be displaced by the examining fingers. They do not encroach so closely upon the pelvic wall, and are generally harder to the touch. Intra-lignmentouH fibroids are dis- tinguished by their close connection with the uterus, and their unyielding feel to the touch Cervical fibroids are usually easily recognised by the protuberance in the lip affected, and the fiattened appearance of tho opposite lip. Treatment. This may be divided into pdlUdiivc and r(uliv(d; or mc.dicdl and nunjicdl. It may be stated at tho beginning, that a serious operation should never be under- taken just because a woman has a fibro-myomatous tumor, the growth must in some manner menace life or health, and not be amenable to other treatment. It may also be stated that all medical treatment is absolutely ui.;?les8 in pedunculated subserous tumors. The hypodermatic use of crffot has, in some cases, caused a cessation of growth in interstitial tumors, and even their extrusion, and is therefore applicable for the treatment of such growths, as well as the submucous variety. The effect of ergot is to cause comprestJon of the blood vessels, by producing more or less marked contraction of the muscular structure of the tumor. The drug should be used in the form of ergotine, from one to two grains being injected into the fleshy part of the thighs or buttocks twice daily, the dose being governed largely by the uterine pain produced. Instead of hypodermatic DISEASES OF THE UTERUS— BENION NEOPLASMS. 269 inj(>ctions, dram doses of fluid extract of ergot, or two grain capsules of ergotiue may bo given by the moutli three times daily, or if it disagrees with the stomach, it may be mixed with four ounces of water, and administered by the rectum. Fluid extract of hydrastis, in half dram doses, may also be used with benefit, but the chief advantages from its use lie only in the effect it has in checking hemorrhage. The bromides and iodides, arsenic, mercurials, and such like, do not possess any positive therapeutic value. Among recent remedies (jdhxinism plays an important part, especially the method introduced by Apostol; The method of application,'and the benefits to bo derived from this class of treatment, has already been referred to when speaking of the practical application of electric currents. Subperitoneal tumors, tilling the pelvis and causing much distress, can at times be dislodged by pressure upwards through the vagina, with the patient in the genu- pectoral position. Hemorrhage may be treated by dilata- tion of the cervix, repeated curettage, and subseciuent application of tincture of iodine, or carbolic acid to the endometrium. Beside the administration of ergot to diminish the blood supply, an operation for li<j(dure of the uterine nrterios, for a similar purpose, is recommended as giving beneficial effects on many tumors, the peduncalated and subperitoneal excepted. With the patient in the dorsal position an incision is made on either side of the cervix, and the connective tissue pushed away until the uterine artery can be felt pulsating. A pedicle needle, armed with a ligature and guarded by the finger, is passed from behind forwards through the broad ligament, above the artery, and after the withdrawal of the needle, the ligature is tied. The artery on the opposite side is tied in the same way, care being observed in each case to avoid the ureters. 270 MEDICAL AND SURGICAL OYNJICOLOOY. Ooplinrcctomif. It lins been stnted that at tlu^ iiuiiio- pnuse, uterine tumors may undergo retrograde* cliangc^s, and that the symptoms produced by them may gradually disappear, when menstruation has ceased. With this end in view, oophorectomy is frequ(uitly performed to bring about the menopause prematurely and, if the case has been properly selected, will likely produce the desired effect. Large tumors, those which are soft or cedematous, pure submucous growths, subserous ones with broad bases, tibro-cystic growths, or those which produce painful pressure symptoms, should not be treated by this operation. Cervical fibroids are not amenable to palli- ative treatment, and should be removed. When peduncu- lated and small, they may be twisted off; if large, and the pedicle thick, the mucous membrane may be incised all around close to the cervix, and the remainder of the pedicle cut through, after which the mucous membrane is stitched over so as to close in the stump. When sessile or distinctly submucous, the capsule should be incised and the tumor enucleated. After trimming the margins, the raw surfaces are coaptated by deep sutures. If unable to do this, or if there is troublesome hemorrhage, the bed of the tumor, and the vagina as well, should be packed with iodoform gauze. Intra-uterine polypi, smaller than a child's head, may be removed in the same way as the cervical, the cervix having been previously dilated to such an extent as will permit the extraction of the tumor. In cases where the attachment of the pedicle is high up, or difficult to reach, or where there is fear of hemorrhage, a pair of light forceps may be clamped on the pedicle at its attachment to the uterine wall, and the pedicle cut through with scissors. The forceps, carefully surrounded with gauze, are allowed to remain in situ for some hours, when they may be removed. DISEASES OF THE UTERUS — BENKiN NEOPLASMS. 271 The nature of further operations for utoriuo fibromntu will vnry ncconliug to tho situntiou niul nttnchmout of tho tumorH. Tlioy may bo thus clnssifiod: 1. iiimjAc myomrc- tornij, or romovnl of the tumor without any of the uterine tissue by excision or enucleation. 2. Hysto'cctoniij, tot((l or pdi'ildl, or removal of more or less of the uterine tissue with the tumor. Myomectomy. When it is jw^sible to remove the tumor from the uterus without destroying the organ, it should be done. The operation is called myomectomy, and is suitable for all subserous growths, and for such interstitial ones as can be enucleated without entering the uterine cavity. The (ibdomiiKil incision. The operation for opening the abdominal cavity has been known by various terms, (jastrotoniy, \ap<ir(itomy, and (ihdominal section, but lately the term ecvliotomy has been introduced, which, while more fully expressing the meaning to be conveyed, is classically correct. The incision should be made in the line of the linea alba, between the umbilicus aiid symphysis. After incising the skin and adipose tissue, the aponeurosis is reached, i nd after carefully dividing this structure the recti muscles are brought into view. These are next separated in the median line, exposing the subserous areolar tissue. After cutting through it, and the peritoneum brought into view, the latter is picked up between two pairs of forceps and incised with the point of a scalpel. It is best to make the first opening not more than two and a half inches long, as subsequently it may be enlarged, should circumstances demand it. Care must be taken not to incise too lo>^^ lest the prevesical space be opened or the bladder wounded. After the abdominal incision is complete the libro- myomatous uterus is brought up, if necessary, partially or wholly through the wound. If there be danger of copious hemorrhage, an elastic ligature may be placed ^>. IMAGE EVALUATION TEST TARGET (MT-3) // // y ^ .^""^^^ %< C^r i/x f/- 1.0 I.I 28 |50 '""= t 1^ IL25 i 1.4 6" 2.5 22 1.6 Photographic Sciences Corporation 23 WEST MAIN « TJ'EET WEBSTER, NY. .4580 (716) 872-4503 4>- rtV iV ,s% '•"is f^ 272 MEDICAL AND SURGICAL GYNECOLOGY. around the uterus and broad ligaments, below the tumor or tumors to bo removed. When the pedicle is large its capsule may be incised a short distance from the uterus, its fibrous tissue enucleated, and the capsule sutured over the base firmly enough to check all oozing. In some cases it is easier to cut the pedicle wedge-shaped, with the thin edge extending up to, or into the uterine wall, and sew up the flaps that are left with deep and superficial rows of sutures. A subserous Lumor without a pedicle may be enucleated and its bed sewed up in a similar manner. Closure of the (ihdominal incision. Strict attention should always be paid to the proper closing of the wound in the abdominal parietes. The methods vary much, but they all aim chiefly at avoiding the subsequent occurrence of ventral hernia. Three loading principles should be observed in order that good results may follow. The apposition of the raw surfaces sh./.M be as broad as possible. Each divided structure should be placed and kept opposite its fellow, peritoneum with peritoneum, muscle with muscle, fascia with fascia, fat with fp.t. The sutures should not bo removed too early. The material used for suturing may be divided into absorbable and non-absorbablo agents, the chief among the former being catgut and kangaroo tendon, and among the latter, silk- worm gut and silk. Methods. Suture in mass or through find through suture. For this class of suture either silk-worm or silk may bo used, but the former is tho one almost universally adopted. The needle is inserted into the skin at the upper angle of tho wound, about throe quarters of an inch from tho margin of the incision, and, as it passes through each layer — fascia, muscle and peritoneum — they are separately picked up, so as to make certain of their being included in the suture. The needle is carried through on the opposite side in reverse order. The sutures are placed DISEASES OP THE UTERUS— BENIGN NEOPLASMS. 273 about throe to tho hicli, and, after nil nro inserted, the ends ,Tro gathered up so as to bring the wound together care- fully, and are then tied. Some operators make the sutures include only the structures overlying the peritoneum, the latter being left intact. Buried or tiei- suture. For this purpose catgut or kangaroo tendon is used. By means of a continuous suture tho peritoneum is first closed. Next the muscular layer is drawn together, next the fascial layer, and finally the skin. Comhined method. By this is meant the combination of suture in mass and of the buried suture. When the through and through sutures are being inserted a few silk-worm sutures are passed through the aponeurosis only, and when tied, are left as buried sutures. Hysterectomy. By hysterectomy is meant partial or total removal of the uterus. It is termed complete when the cervix as well as the body has been removed; partial when the cervix has been left. Some surgeons speak of the operation as total htjstereetomij, even when the cervi'c is left behind. Another division is made into extra- peritoneal and intra-peritoneal, according as the pedicle is treated outside or inside the peritoneal cavity. Indications for operation. Mere bulk may of itself bo a sufficient reason. Rapid growth or the development of cysts in soft cedomatous tumors ; suppuration and sloughing; excessive metrorrhagia which every palliative measure fails to check; pressure on adjacent viscera pro- ducing obstruction; uncontrollable pain; the presence of abundant ascitic fluid, are all clear indications for operation. Besides tho instruments commonly used in coeliotomy, special large forceps should be provided to clamp on large vascular areas ; also two trustv^orthy clamps for the constriction of the pedicle, and I'or tho latter purpose Koeberle's serre-nonud, or Tait's modification of it, is 274 MEDICAL AND SURGICAL GYNECOLOGY. probably the most efficient. The Trendelenborg is the position most often used. After the abdominnl cavity lias been opened, information is obtained as to the size, position, relations and possible adhesions. By moans of a large vulsellum, or myoma screws, the tumor is brought up into the wound, and ligature of the broad ligament proceeded with. When the tumor is well drawn up, these ligaments will be put on the stretch. Eacl broad ligament Fig. 87.— Application of ligatures in ablalion of the fibroid uterus. is tied and divided, after placing pressure forceps on the uterine sides, outside the ovaries and tubes. If the ligameiits are very broad, two or even three successive applications of the forceps, each below the previous one, and as many ligatures, may be necessary. The tumor being delivered as fully as its attachments to the vagina and the lower portion of the broad ligament will permit, the bladder is pushed well down under the pubes in front, and sponges are packed in behind to keep the intestines out of the way. It must now be decided in what way the pedicle is to be treated, whether extra-peritoneal or intra-peritonenl. Extrn-peritoncdl treatment of the pedicle. The wire of the serre-ncjeud is passed around the pedicle, care always being taken to avoid the bladder, and, when drawn DISEASES OF THE UTERUS — BENION NEOPLASMS. 27o uiJ, tho free ond is made fast to tho movonble pin and ?is mucli constriction made, by turning tlio thumb screw, as will arrest the circulation to its fullest extcuit without cutting. Pedicle skewers are inserted across the incision, either parallel or crucially, just above the wire, and the tumor removed close to them, leaving only enough tissue to give firm hold. In placing the serre-nooud, it should be so arranged that the constricted wire will be well within the parietal wound, and the handle so that it will lie over the pubic region. There are other modes of constriction besides the wire, such as the elastic ligature, and tho clamp, but the method described seems to be the favorite one. The parietal incision is closed in the usual way as far down as the pedicle, tho lowest stitches being inserted so as to draw the tissues closely around it. The use of styptics, such at, icrchloride of iron or the actual cautery, to the stump is x-ecommended by some for their charring effects. Subsequently the wound is dressed in the usual way. The whole stump above the wire is removed in course of time by pressure necrosis, but it is not necessary to allow the wire to remain for that length of time, but may be removed as soon as the new adhesions are sufficiently strong. Afti'r tlu pedicle separates, a deep granulating excavation is left, which rapidly fills up even with the skin. Intrd-pcriiom'dl trcxdmod of fh'.> pedicle. The opera- tion in its first stages is similar to that already described. If there is fear of hemorrhage an elastic ligature, or wire clamp, may be placed temporarily around the cervix, but this procedure is scarcely necessary when the uterine arteries have been controlled by the broad ligament liga- tures. With the same precautions observed for tln^ care of the surrounding structures as already described, an incision is made a little above the attachment of the bladder, and a corresponding incision behind, by which a cup-shaped cavity is cut out and the tumor removed. 276 MEDICAL AND SURGICAL GYNECOLOGY. Tho cavity thus formed in the cervix is now closed by buried cntgut sutures, and by a separate row of silk to unite the peritoneum. The abdominal incision is then completely closed. Complete hysterectomy. After ligature of the broad ligaments according to the manner described, another and lower deligation of them is carried out, great care being observed not to include the ureters. The peritoneum is next divided all around the cervix, below the constricting ligature, if one has been used, avoiding carefully the bladder in front and the rectum behind. An opening is made on the top of the vagina, the point being indicated by the insertion of a probe into that canal, and with a few strokes of the scissors the division is completed as close as possible to the cervix. After securing the few bleeding points, the anterior and posterior flaps are united by a continuous catgut or silk ligature. After carefully cleans- ing out the peritoneal cavity, the parietal incision is closed; should necessity demand it, drainage may be established through the vagina. The vagina should next be loosely packed with iodoform gauze and changed daily after the second day. CHAPTER XXV. DISEASES OF THE UTERUS CONTINUED. MALIGNANT NEOPLASMS. CANCER OF THE UTERUS. This disease occurs most frequently between the ages of forty and fifty, although earlier periods of life are not exempt. It was formerly thought that cancer was limited to the cervix, but later experience has shown that cancer of the body, although not so frequent as cervical cancer, is not rare. DISEASES OF THE UTERUS— MALIGNANT NEOPLASMS. 277 Cancer of the cervix. Tho gront predisposition of the cervix to the development of cancer hns been noticed by all observers. More than one tliird of nil cases of cancer in women occur in the cervices of inultipane, and the frequency is explained by the fact that iho cervix is so often subjected to irritation, laceration, ero.^'ion, and infection. Pdtholofi/i. From a clinical point of view, and when seen at the start, and before the primitive aspects of the part have been altered by their spread to adjacent struc- tures, four classes may be distinguished. 1. PapiUarij. (Superficial cancer of the cervix, vege- tative or cauliflower cancer.) This form begins on the vaginal portion of the cervix, and may for a long time be limited to it. Often it starts from cylindrical epithelium which ha;i invaded the external surface. It may take on a fungous appearance, the os and healthy lip being hidden beneath it, and for a long time may show no tendency to spread. Sooner or later, however, it attacks the cul-de-sac and passes on to the peri-uterine tissues; or the extension may take place along the cervical canal. 2. NoduJar. (Parenchymatous cancer, cancerous nodosities, circumscribed or infiltrated cancer.) This form starts as one or several nodules in the mucous membrane of t'' j cervix, on either the external or internal surfaces, witl ^-eration only late in the disease. In this form the whole organ soon becomes involved, as well as the adjacent tissues. 3. Cancer of the cdvifi/. (Boring or eating cancer). This form develops first in the cervical mucous membrane by an infiltration which soon ulcerates and causes the slow destruction of the part by erosion, and there are cases of this kind where the cervix becomes a mere shell. The body of the uterus is early involved, then the peri- uterine connective tissue, and the vagina last or not at all. 278 MEDICAL AND SURGICAL GYNAECOLOGY. 4. Vdffi'ndl This is far moro oommon tlinu the otliors. It begins in the postorior cul-de-sac and invades equally the cervix and the adjacent j)ortion8 of the vagina, i^ro- ducing extensive ulceration. Histologically the three kinds most often found are: — 1. Pavemenf cjiitlicliormt (sciuamous epithelioma) is that variety often found in the superficial forms — papillary and vaginal. In the variety called lohnhdcd, cellular masses lie between the bundles of muscular fibres. In the tubulated, anastomosing cylinders, stuffed full of epithelial cells, penetrate between the muscular trabecular. 2. Ctjiindn'cal epithet iomd is usually the form which begins in the cervix and spreads along its cavity, and resembles that of the uterine body. It begins by a typical glandular proliferation (adenoma), and ends as an atypical proliferation ( malig- nant adenoma), which is simply an epithelioma. 3. Carcmomd or atijpirrd epdiielioma is not clearly dis- tinguished from certain forms of tubulated pavement epithelioma. It is characterized by poly- morphism of its cells which correspond to those of the al- veolar wall, or to those of the gland ; also by their disjoosition in masses within the alveoli, the walls of which are formed by anastomosing bands of connective tissue. When the fibrous stroma is small in amount, and the cells are swollen and predominant, t' e tumor is called enceplKiloid; when hard and dry it is called sct'ri-lius. Extension. At an advanced period of the disease, the characteristics peculiar to each form are lost in the destruction caused by its extension. Extension to the vagina may be found at the outset. It may occur rapidly 88. - Cylindrical epithelioma of ihe cervix. DISEASES OF THL UTERUS — MALIGNANT NEOPLASMS. 279 in the pnpillr.ry form, and may oven ronch the vulvn. The body of the organ is very soon involved in the case of tumors of the cervical cavity, and, in the nodular form, it may bo infected from the first. The pelvic connective tissue may be invaded from the cul-de-sac, the cervix, or the fundus, by which the uterus becomes imprisoned, as if set in plaster of Paris, and the broad ligaments bocome thick- ened and shortened. The ureters, instead of being pushed aside, become assimilated by the neoplasm, and ulceration and fistuhe may re- suit; or they maybe- come compressed producing hydro- nephrosis and allied conditions of the kid- ney. The rectum is seldom involved, ex- cept in far advanced cases, when the vagina may be found open- ing both into the bladder and rectum. The peritoneum re- sists the ingrowth by the production of adhesions, and is seldom opened. The ovaries and Fallopian tubes may all become affected, and, lastly, there may be metastases to distant organs, as the liver, kidneys, stomach, and lungs. Symptoms. The onset of the disease is insidious, and may exist for some time while the patient preserves every appearance of health. The earliest symptoms are in no way characteristic. The attention h. often first attracted by a small loss of blood at other than the regular periods, or appearing at variable times after the menopause, especially after some exertion, or after coitus. Leucorrhoea, Fig. 89 — Epithelioma aflecting both lipsof Ltrvix, vagina and bladder. 280 MEDICAL AND SURGICAL GYNAECOLOGY. without nny spocinl < hnractoristics npponrs. to^othor with somo diffuse pelvic pniii. Such Hymptoms sliouid always excite suspicion in one who has passed for some time the climateric period, and a local examination insisted upon. Digital exploration recognizes the induration, or the papillary and ulcerated condition. The speculum tlemon- Etrates the livid aspect of the tumor, the yellowish surface of the ulceration and the fungous vegetations if present. As the disease advances, hemorrhages become more frequent. The vaginal discharge becomes reddish and has a peculiar, characteristic, as well as disgusting odor, and so abundant and acrid that it causes distressing erythema of the thighs and pruritus of the vulva. The local pain now becomes more or less severe, with radiation of it in different directions. By digital examination the vaginal pouches may be found invaded, the uterus more or less fixed by extension of the morbid processes, and the cervix changed by the advancing disease. The third stage, or that known as the cancerous cachexia, is indicated by digestive disturbances, anorexia, constipation, and by the skin assuming a peculiar pale yellow tint, and by becoming harsh and dry. At this time there may be present cystitis, intolerable neuralgia, phlegmasia dolens, and genital fistuhe, while local exam- ination will reveal wide extension to the adjacent parts. Successive attacks of subacute unumia may co-exist with these, or the urremia becoming chronic, the patient gradually sinks into a semi-comatose condition, and quietly dies. Peritonitis, by extension or perforation, may bring about speedy termination, or septicemia, especially in neglected cases, may alone be the immediate cause of death. Diagnosis. In this disease, perhaps mon* than in any other, the necessity for early diagnosis is imperative to be of much benefit. The early stage can never be dijignosi'd with certainty without microscopical examiuRtion of an DISEASES OP THE UTERUS— MALIGNANT NEOPLASMS. 281 excised piece from the suspected part. As already stated, when speaking of endocervicitis, it may resemble follicular erosion, but it differs from it in having scmewliKt elevated and indurated edges. The :'aw surface in both conditions may bleed with equal readiness, but if papillary projec- tions are already present, in cancer they break down much more readily. It may be mistaken for a submucous fibro-myoma protruding from the os, but if carefully examined, a healthy ring of cervical tissue will be found encircling the neoplasm. When the disease begins in the cervical canal, early diagnosis may be extremely difficult. It may have made considerable progress, and yet there may be nothing abnormal in appearance. The chief clinical distinction between beginning cancer and endocervicitis will be found in the fact that the discharge in the latter condition always retains its mucous consistency, while in cancer the discharge is mostly of a watery consistency, and has an offensive odor. A nodule may be suspected to be malig- naTit if it is hard and protuberant, the exterior of a bluish color, and the patient over thirty five years of age. Advanced stages of cancer of any part of the cervix are readily diagnosed by the symptoms already mentioned, but in such instances it is usually impossible to recognize from what part of the cervix it originated. The proijuosis is not very good, even with operative interference. Could the disease be discovered in its earliest stages, total extirpation might give better results than they usually do. When the pelvic connective tissue or lymphatics are invaded, or the entire thickness of the cervix involved, a p' rmanent cure cannot be held out. Treatment. Treatment of cancer may be divided into railirdl and jHiUiative. Radical. Radical operation, to be successful, pre- supposes conditions which will allow of the total removal of all disease. There must be complete absence of exten- 282 MEDICAL AND SURGICAL GYNECOLOGY. sion to any surrounding organ or gland, to tho ijoritonotim, broad ligament, bladder, rectum or vagina. The utoruH must bo freely movable nnd unassociated with severe pelvic pains. When these conditions exist operation should at once be proceeded with. Hij/h (imput<itioti of the cervix by one of the methods described when speaking ol liypertrophy of the cervix is recommended, and has been frequently performed, but the operation is not upheld now as being the best, because independent cancerous nodules in the body of the uterus have been observed, and second, the operation, when properly performed, is just as difficult and nearly as serious as complete extirpation. Vaginal hysterectomy. Colpo-hysterectomy. The patient is placed in the dorsal position, and the knees kept apart and the thighs flexed on the pelvis by means of Clover's crutch. A large Edebohls' speculum is inserted into the vagina, and by means of scissors and a sharp curette, exuberant tissue is cut or scraped away. The uterus being next curetted, and the interior packed with a little iodoform gauze, the cervix is closed with a few sutures. After again thoroughly cleansing the vagina and fornices, a strong vulsellum is introduced into the lips of the cervix and the uferus drawn down. Except when the cervix can be brought outside the vulva, lateral retraction will be of advantage to give the operator more room and light. A pair of scissors is made to cut through the mucous membrane around the cervix, at a distance well clear of the disease. By means of the finger, or by the handle of a scalpel, or by closed blunt-pointed scissors, the mucous membrane is elevated from the cervix all around, the uterus being drawn forward and backward to facilitate the manipulations. In front great care mus' be observed not to open into the bladder, and if there is any doubt, the introduction of a sound through the urethra will serve as an excellent guide. When the mucous DISEASES OF THE UTERUS — MALIGNANT NEOPLASMS. 283 mombrnno has been rnisod from the cervix as high ns the pcritonoum, that mombrano is perforated behind and in front, and a few layers of gauze, secured at one end by means of a ligature, pushed into Douglas' cul-de-sac, to keep the bowels out of the way. The uterus is next well drawn down and the division and closure of the blood vessels of the broad ligament proceeded with. For this purpose a variety of plans have been devised, but the Fig. go — Vaj'inal hysterectomy by ligature. principal ones may be described under two headings, by h'gfitii7'es, and by chimps. Bji lujatnrc. The material for ligature may bo either good reliable catgut or silk. A pedicle needle armed with the ligature, and guided by the index finger, is introduced behind the broad ligament, close to the uterus, and passed through and made to emerge in front of the ligament as high ui) above the uterine artery as possible. Another ligature is oassed in the same way on the opposite .'•ide, and, after being carefully tied, those portions of the broad 284 MEDICAL AND SURGICAL GYNAECOLOGY. ligaments included within the ligatures are divided. The uterus may now be pulled still farther down. If the first ligatures have not secured enough of the broad ligaments to bring the body of the uterus fairly into view, others may be placed on each side higher up. The uterus being now drawn weJl down, the tubes and ovaries may be felt. A ligature is passed over the infundibulo-pelvic ligament, and after being carefully tied, is divided. The corre- sponding ligament on the other side will then be very readily ligated, and, after division, the uterus will be free. If there is much difficulty in bringing the tubes and ovaries into reach they may be left behind, the last liga- ture passing over the tubes, as they lie in the free margins of the broad ligaments. If the tops of the broad ligaments are beyond easy reach of the finger, or the uterus consider- ably enlarged, inversion of the fundus, either in front, or behind through the opening in Douglas' cul-de-sac, will always bring them within reach. After removal of the uterus the gauze packing is withdrawn, and steps taken for the management of the vaginal wound, for which various methods have been adopted. The broad ligament stumps may be drawn down with bullet forceps into the vagina, and a full-curved needle introduced through them on either side, entering anteriorly through the vagino- peritoneal margin, and emerging posteriorly in the same manner, and the ligature tied. The opening in the vaginal wall is now closed with a few sutures. Some surgeons recommend that simply the peritoneum should be sutured to tiie vagina, others that the vagina alone should be sutured, while others leave all the structures to fall into apposition and unite as best they can. The vagina may now be packed with iodoform gauze. When the vaginal wound has been left open, a few strips of gauze should be put in the slit, particularly when drainage is necessary. DISEASES OF THE UTERUS — MALIGNANT NEOPLASMS. 285 IVic clamp method. The first steps in this method are the same as have already been described. The peritoneum is opened in front and behind, and if it be convenient to do so at this stage of the operation, may be attached to the margins of the vagina. A clamp is now placed on the base of the broad ligaments, one on either side, and the ligaments divided close to the uterus. The uterus is now drawn lower down, and the remaining part of the ligaments Fig. 91.— Vaginal hysterectomy with clamps. included in a second pair of clamps, and also divided. The handles of the forceps are securely tied to prevent them from springing open, and wrapped with gauze, after which the vagina is lightly packed as before. The clamps are allowed to remain in place for thirty six to forty eight hours, after which they may be removed. Instead of incising the mucous membrane around the cervix, the thormo-cautery is sometimes used, and as the uterus is 286 MEDICAL AND SURGICAL GYNECOLOGY. being separated from the bladder, the tip of tbo caut(^ry knife is kept almost constantly in close contact with the uterus. By this method the operation practically becomes a bloodless one. Abdominal hysterectomy is at times performed for cancer of the cervix, the advantage claimed for it being that more of the broad ligament can be removed, and by this means it is possible to get farther away from the disease. A combination of the two methods, vagino- abdominal hysterectomy, is also now performed, the upper portion of the uterus being freed by abdominal incision, and the lower portion through the vagina. Sacrnl hysterectomy. Kraske's operation for cancer of the rectum has been adapted to the removal of a cancerous uterus, but the operation has not received much, if any encouragement. Palliative treatment. When the disease has pro- gressed to such an extent as to make radical treatment inadvisable, only palliative treatment is left. Among the various remedies and forms of treatment, curettage, with subsequent cauterization by means of the thermo-cautery, is one of the best. Another efficient treatment consists in packing the crater formed after curettage with a fifty-per- cent solution of chloride of zinc, the vagina and bladder being protected by gauze moistened with a solution of bicarbonate of soda. If there is a tendency to hemorrhage after the removal of the slough, or practically at any time, it may be checked by vaginal tamponade, either alone or combined with some styptic, such as perchloride of iron. Local antiseptic treatment must be constantly kept up. Injection of a one-per-cent solution of creolin is valuable both as a heemostatic and antiseptic. Peroxide of hydrogen, or a weak solution of permanganate of potash, has a decided cleansing and deodorizing effect. Equal parts of iodoform and charcoal will relieve pain and counteract the objectionable odor. Suppositories made from chloral and DISEASES OP THE UTERUS— MALIGNANT NEOPLASMS. 287 tannin (an. gr. xv.) will relievo pain, lessen hemorrhage, and counteract the offensive odor. Narcotics will invariably become necessary at some time during the course of the malady, and it has been claimed that when opium is freely used, the progress of the disease is to some extent retarded. So far no drug has been found that will cure cancer, although from time to time new specifics have been praised. Condurango bark, chian turpentine, methyl blue, have all enjoyed a short lived celebrity. Not much more can be done than to sustain the general health as far as possible, and treat complications ns they arise. CANCER OF THE CORPUS UTERI. Modern means of investigation have shown that primary cancer of the body of the uterus is not so rare as was once thought. Two varieties may be distinguished, epithclionui and adeno-carcinoma or malignant adenoma. Epithelioma occurs as a diffuse growth of villi through- out the whole uterine cavity, and consists of an atypical development of epithelial cells of different sizes. It has little tendency to involve the mucous membrane of the cervix, but the uterine wall, little by little, is eroded and destroyed, and the interior of the uterus converted into an ulcerated cavity. Adeno-carcinoma occurs as an isolated fungoid growth with a large or small base, and at times has the form of a polypus. Histologically the tumors are corajjosed of anastomosing tubules filled with cells. The first layer of cells implanted on the wall is regularly cylindrical, and the successive layers are formed by polyhedral cells which are, at times, of the pavement variety. The interior of tiie mass also contains alveoli, lined with one or two layers of epithelial cells, as well as cavities containing mucous and free cells. At a later period, in both varieties, metastatic nodules form in various parts of the parenchyma, 288 MEDICAL AND SURGICAL GYNJICOLOGY. and even under the peritoneum, forming protective ad- hesions and metastatic noduh^s there. Frequently tht>se metastatic nodules are found superficially in the vagina, and deeply in the ovaries and tubes. Symptoms. Hemorrhage is the primary symptom, and, as in cancer of the cervix, it is usually accompanied by a serous discharge, of a reddish color and disagreeable odor, and with this there is often a discharge of small shreds of tissue from the broken down parts of the fungosities. Symptoms of uterine inflammation are often noticeable, Fig. 92. — Medullary cancer of body of uterus. but, as the disease becomes more advanced, the pain takes on a paroxysmal character which is remarkable and also pathognomonic. These crises have none of the character- istics of colic, and are peculiar from their appearance, at almost regular hours, once or twice a day. Bimanual examination shows the organ to be increased in volume. It remains movable for a long time, but finally becomes imprisoned by adhesions. The cervix is found free from disease, but often is much softened a:.id partly open. DISEASES OF THE UTERUS — MALIGNANT NEOPLASMS. 289 The sound rovonls nii increase in the capacity of the uterus, and the presence of irreguhir masses. The general health fails as the neoplasm develops and terminates in cachexia. DifUfiiosis. In the early stages this may be very difficult. The hemorrhage, the serous dischar?^e, the in- crease in the volume of the uterus, itnd the results of intra-uterine exploration, constitute the clinical elements of the case, while the microscopical examination of por- tions removed by the curette clearly differentiates between cancer and metritis without malignant neoplasm, or be- tween carcinoma and sarcoma. Treatment. When seen sufficiently early the only treat- ment is total eradication of the uterus by hysterectomy. SARCOMA. Sarcoma is a comparatively rare form of malignant disease of the uterus. It may occur at any period of the sexual life of the woman over twenty years of age, but is most often fouad just before, or just after the menopause. There are three well defired forms of sarcoma. Fibro-sarcoma. This form occurs in tumors or masses, and has a striking resemblance in growth and structure to fibro-myomata. Like them they occur as submucous, interstitial, or subserous tumors, and have their origin also in the parenchyma of the uterus, but instead of being limited by a loose capsule, it is, as a distinctive characteristic, deeply rooted. The vast weight of authority is in favor of the view that they are malignant transformations or degenerations of the ordinary fibro- myomata. Histologically they show a proliferation of round, and in places fusiform cells, more or less replacing the normal tissues of the uterine wall. When they have a pedicle it is apt to be fibrous, intimating that it has come from a degenerated fibro-muscular polypus. They give rise sometimes to metastatic growths in distant parts 2iK) MEDICAL AND SURGICAL GYNAECOLOGY. of the body, but show little tendency to disintegration or trnnsformntion. Occasionnlly cystic degeneration takos place, giving rise to cif^to-sarrom'i. Diffuse sarcoma. SarcomH of the endoraetriu~n closely resembles the typical form of carcinoma of the sau e structure. The term is used to desigiiate a new growth proceeding from the connective tissue of the uterine mucous membrane, consisting mostly of small closely packed round cells, though sometimes spindle-shaped, and producing soft villous or lobulated tumors of an encepha- loid aspect. The tissue does not break down as readily as that of epithelioma, but is apt to fill the uterus and present at the cervix. The uterine walls are gradually invaded, and become a mere shell filled with the encepha- loid mass. This form is found most frequently in young women. There is a rare variety, mah'tpuint (Iccichioma (sarcoma uteri deciduo-cellulare). Many authorities dispute this variety of sarcoma as a particular form, considering it simply a mixed sarcoma. It is developed soon after parturition or abortion in the placental remains or decidua, and is composed of polymorphous decidual cells, and giant cells embedded in connective tissue. Sarcoma botryoides, or grape-like sarcoma (papillary sarcoma of the cervix) is a variety which appears in the c'?rvix, and as such is characterized by its grape-like form. Clinically, it is extremely malignant. Tire mass is soft in consistence, and grows to a large size, often filling the vagina. The disease spreads along the mucous membrane into the uterus, and to the vagina, and finally invades the pelvic connective tissue and peritoneum. Symptoms and course. All forms run a more rapid course than the corresjionding carcinomata after the symptoms first attract attention. Fibro-sarcoma gives rise at first to the same symptoms as fibro-myoma, and it is stated that when a tumor, previously existing as a fibro- DISEASES OP THE UTERUS— MALIGNANT NEOPLASMS. 29J myoma, begir s to grow Rt th > me^iopnusc, it is uiulorgo- iiig sarcomntouH trnasfonimtion. Wlioii post-climateric growth occurs, two symptoms soon appear. One is jjain, owing to tension or invasion of the peri-uterine connective tissue, the other is marked deterioration in the general ?'ealth. If the neoplasm has developed from a submucous fibro-myoma, there will be severe hemorrhage, and pain from the efforts of the uterus to expel the tumor. As it advances in growth, in addition to occasional violent hemorrhage, it may cause a sanious hydrorrhcua, and the discharge will sooner or later take on an ott'ensive odor. Owing to the intense anjemia, sapra^nia, and marasmus, death is readily produced. Death may occur from peri- tonitis, intestinal obstruction, or from pressure on the ureters. In the diffuse form the symptoms are not dis- tinguishable from carcinoma affecting the same structures. Diagnosis. With the exception of the rare form, sarcoma botryoides, it cannot positively be diagnosed without microscopical examination. The clinical symp- toms must be carefully observed, and in this there are two points desiTving special attention; first, the rapid growth, at or about the menopause, of a tumor previously known to exist; and second, a more marked ansemia and deterior- ation of health than is ever found associated with the same stage of growth of a benign tumor. The treatment is, as in other forms of malignant neoplasms, palliative or radical. If the uterus is movable, and there is no metastasis or invasion of the vagina, total extirpation of the uterus is at once to be undertaken. 292 MEDICAL AND SURGICAL OYN.ECOLOOY. CHAl'TER XXVI. DISEASES OF THE FALLOPIAN lUBES. Malformations. Tlu^ ubes show a numbor of devolop- mentai anomalies, but thoy arc of little importance except in the study of the etiology of tubal gestation. Accessory fimbriated extremities are not uncommon. There may be an accessory uterine orifice, or the whole duct of the tube may be duplicated. In connection with imperfect develop- ment of the whole sexual apparatus, the tubes may also be non-developed; they may possess an abnormally small calibre; they may be without any lumen; or they may bo entirely absent. On the other hand, the tubes may show an abnormally great development, with corresponding patency of the canals. They may be congenitally displaced backward and downward into Douglas' pouch, or they may be wound in a spiral, or abnormally contorted. SALPINGITIS AND ITS COMPLICATIONS. The important position taken by inflammation of the uterine appendages has but recently been generally admitted. To thoroughly understand the close association of inflammation of one organ with that of the other, the common embryonic origin of the uterus and tubes, and the close association of the ovaries, must be borne in mind. The various coats of the tubes and ovaries are continuous with each other, a fact which explains the possibility of ascending salpingitis following endometritis, just as ascending pyelitis may follow chronic cystitis. The ovary, which is connected with the tube by the tubo- ovarian ligament, and almost in direct contact with the ampulla, may also be easily infected by continuity. In addition, these organs are intimately bound together by important vascular and lymphatic vessels, so it may be said that there is scarcely ever a salpingitis unaccompanied by ovaritis, or an ovaritis uncomplicated by salpingitis. r EASES OF THE FALLOPIAN TUBES. 293 Non-cystic salpingitis. Cystic snlijingitis. Salpingitis and its results may be studied from n clinicni nn<l anntomicnl standpoinl. under the following classification : — (<i. Acute catarrhal. h. Acute purulent. ('. Chronic parencliymatous. ( Pachysalpingitis. ) (a. Hydrosalpinx. -. h. Pyosalpinx. {('. Hematosalpinx. Acute catarrhal and purulent salpingitis. The chief causes of salpingitis are intlammatory conditions of the uteriis, gonorrlueal infection, puerperal infection following parturition or abortion, and contamination from surgical exploration or interference. P(ifli<)J<>(/i/. In the acute caiarrhal form the tube is swollen cylindrically, from about the size of the little finger to that of the thumb, and owing to its lower border being attached to the broad ligament, becomes more tortuous. The lesions are especially marked in the mucous coat, being thickened, infiltrated with round ct^Us, and moistened with abundant mucous secretion. The normal folds are swollen, and covered with lateral newly formed vegeta- tions. In places they are agglutinated, enclosing spaces between them, giving the appearance of glandular forma- tion. The epithelial cells, as a rule, maintain their integrity, and the fibro-muscular coat is but slightly affected, there being only a hyperplasia of its substance. The fimbriated extremity is at first jjatulous, but later the fimbrire become contracted and folded up. The uterine ostium generally remains patulous, through which the excess of mucous is discharged. In some cases a few drops of mucous escape through an uncljsed fimbriated extremity, giving rise to a slight localized peritonitis. In piirnhmt sdlpini/i'tis there will be evidences of extensive inflammation. The tubes are swollen, twisted 294 MEDICAL AND SURGICAL GYNJICOLOOY. and tortuous, and tho fimbria so ngglutinatod as to close tho abdominal orifice. On section it is found to be filled witli a creamy pus, the cavity often resembling a string of beads owing to contraction. The pus can or.sily bo evacuated through the uterine cavity, as the ostium internum is not occluded like the ostium abdominale. The mucous membrane is of a grayish tint, and under the microscope a transverse section shows thick reduplications, forming a system of primary and secondary folds enclosing irregular cavities that look like glands. This thickening is duo to the infiltration of migratory cells in the connective tissue. The ciliated cells are destroyed, and the epithelial cells are changed in shape. The whole thickness of tho wall is also infiltrated with round migratory cells, and the blood vessels are dilated. In the beginning the disease is usually confined to one side, but if left unchecked, is apt to affect the other. Usually some exudate appears on the serous surface, forming adhesions with tho surrounding surfaces, but the greatest amount of localized peritonitis and adhesion is set up by an occasional exudation of pus from the abdominal end, which, when frequently repeated, has the effect of agglutinating the pelvic organs, omentum, and intestines into a matted mass. Accumulations of pus or serum b(^tween the adhesions are occasionally found, sometimes displacing the uterus laterally or forward. Iiif('rstiti<(l sal])ifi(/itis represents an advanced stage of the purulent form. Both tubes will be found involved, and the lesions, instead of being limited for the most part to the mucous membrane, include the whole thickness of the walls, so that they become thickened, hardened, and purplish in color. Sometimes the induration is general; at times it is more marked in places, giving the tube a peculiar nodular appearance. The mucous membrane is dark blue in color; the villi are enlarged, united, and in Ijart destroyed by small celled infiltration. False glands and cystic spaces are thus produced at some distance DISEASES OF THE FALLOl'IAN TUBES. 295 below the surface. The externnl orifice is nlwnys obliter- fttod, but the uterine orifice in more or h^ss pervious. The mesosnipinx may be expanded by the enhirged tube, or it mny be folded up by adhesions, or infiltrated by infiain- matory products. The ovary, which often preserves its integrity in the catarrhal form, is usually affected. It is generally displaced, fixed by adhesions in DoughiH' pouch, or to the sides of the pelvis, or it may suppurate independent of t h e tube. The peritoneal adhesions, which may also involve the omen- tum and intestines, are dense and strong, and are sometimes so firm that they cannot be broken up without laceration of the peritoneal surfaces, or even of the walls of the viscera. Organized bands may extend between the surfaces in all directions, so as to make it difficult at times to determine the relations of the parts after the abdomen has been opened. . Symptoms. As acute salpingitis usually occurs in patients already exhibiting symptoms of endometritis, it is difficult to decide with precision to which lesion the symptoms are due. Pain situated in the neighborhood of the appendage, or in the lumbar region, and radiating upward to the epigastrium and downward to the thigh, is generally present. A bimanual examination elicits tender- ness and fulness on one side of the uterus, and some pain when that organ is moved or displaced by the fingf r. Leucorrhoea is present to a greater or loss extent, and when the menstrual flow appears it is usually very pro- FlG. 93. — Salpingitis with pelvic peritonitis and ad- hesions posterior to the uterus. 2% MEDICAL, AND SURGICAL OYN^EC'^UHIY. fuHo. Gonrrnl conHtitutioiinl HymptorriH mny npprnr, Huch RH n fooling of mnhiiHo, noumlgio pniiis Hcnttorod ovor tho body, and n Blight rino of tompornturo and pulso. Shoulf. muooiiH oscnpo tiirougli tlio outor opening, tlu^ro will bo nn oxncorbntion of tho HymptoniH, charactiTizod by incroawc^d pain in the iliac region, local tympanites, nausea and perhaps vomiting, and other symptoms of a mild form of local peritonitis. When the salpingitis is of the purulent form the symptoms may be similar to those just described, but they are likely to be morci pronounced in character, and slower in subsiding. Should gonorrluBal pus make its escape through the outer ostium, the peritonitis may not be much more severe than that already described, but when the case is one of mixed infection, an extensive pelvic i)eri- tonitis will be set up, accompanied by great tympanites, high temperature, rapid pulse, extensive pelvic pain and tenderness, and as a result, there will be an abundant peritoneal and cellular effusion which becomes hard and solid, like plaster of Paris, and which may partly or entirely fill the pelvis. The symptoms may last for a few days, and after confinement to bed for a few weeks, the patient may, as far as her symptoms are concerned, entirely recover for a few weeks, months, or even years. Sooner or later, however, perhaps after some unusual exertion or exposure to cold, more particularly at the menstrual period, a recurrent attack of peritonitis will make its appearance with the same suddenness as before. In many cases the symptoms do not subside entirely, but remain in a semi- quiescent state, the patient suffering more or less from the milder form of symptoms in the intervals. When the attack results from direct infection during abortion or operative procedure, the symptoms of a general ii ''ection will probably predominate, indicated by chills, high pulse, exaceroation of fever, the temperature rising and falling three or four degrees once or twice daily, being highest in . DISEASES OF THE FALLOPIAN TUBES. 2V)7 most cases in tho afternoon or enrly evening. Other symptoniH of a general peritonitiH m/iy rapidly follow, 8U(rli as abdominal diHtt*nHion, labored riiHpiration, a wt^ak thready pulwe, piirniHti^nt vomiting, and cold clammy perspiration, all indicating that death is near. A vaginal <\xamination will reveal an enlarged and tend uterus surrounded by highly sensitive infiltrated tisE'i' % in which a hard mass may or may not be found. In severe cases abdominal palpation may reveal a tender exudate extending from the enlarged uterus, but when tho symptoms have been mild, there may be nothing but deep- seated tenderness. The symptoms of interstitial salpingitis are those of an ailment which has extended over a considerable length of time, with more or less severe attacks of pelvic inflam- mation occurring at varying intervals. There may be a history of but a single attack of pelvic peritonitis, but that is exceedingly rare. There will more likely be a history of recurrent attacks, with intervals of good health, or of semi-invalidism. during wliich the patient is in- capacitated by pain or discomfort from the ordinary duties of life. Between the attacks the symptoms of endometritis are seldom absent. There will likely bo a burning pain in one or both iliac regions, radiating into the lumbar, gluteal or sciatic regions. Painful micturition and defecation, dysmenorrhoea and intermitteni or constant leucor- rho3a are often present. In the earlier stage, when pus is present, there is apt to be an afternoon rise of temperature, possibly a degree or two, but after the disease has lasted for a length of time, and septic influences disappear, the temperature will probably remain normal throughout the day. Along with these symptoms there may be those of a general nervous disturbance, such as nausea, indigestion, neurasthenia and hysteria. A bimanual examination will reveal an enlarged, hard, tender mass behind or beside the uterus, with more or less immobility of that organ, or 298 MEDICAL AND SURGICAL GYNJICOLOGY. the uterus may be fixed in one side of the pelvis by bands of adhesions, and surrounded by a thickened and hard mass. The discharge issuing from the cervix may be thick tenacious mucous or muco-pus. Tlie uterus itself will bo found in a condition of subinvolution, or of chronic metritis. Prognosis. Catarrhal salpingitis frer^uently ends in restoration of the tubes to a practically normal condition. When the disease, however, has existed once, it is apt to be reproduced by the accompanying endometritis; or a puru- lent salpingitis may be established. Purulent salpingitis may endanger life, owing to the eocape of pus through the ostium abdominale and the consequent local or general peritonitis or abscess formation. There is, as a rule, sterility, or a strong tendency to the occurrence of ectopic gestation. Interstitial salpingitis usually con- demns the patient to more or less chronic invalidism. In some cases it involves all the dangers of pyosalpinx, while in others there may bo a gradual improvement of both the local and general symptoms, a recovery from septic con- ditions, and a final restoration to comparative good health. Treatment. As the disease is asually an extension of endometritis; much may be done to prevent its occurrence. Acute metritis following labor, abortion, or operation, should, as soon as dip^nosed, be treated on thoroughly active and antiseptic principles, and the same advice is applicable in cases of gonorrhoeal infection. It may be necessary to curette the uterus, after which it may be touched over with strong carbolic acid, and the antiseptic treatment subsequently k» pt up by vaginal or intra-uterine douches. The treatment of catarrhal salping' tis is identical with that of endometritis. Absolute rest in bed is neces- sary, and measures taken to relieve congestion, and favor drainage of the uterus and tubes. Hot fomentations should be continually applied over the abdomen and vulva, and a hot water bag beneath the lumbar region. A sharp DISEASES OF THE FALLOPIAN TUBES. 299 saline cnthnrtic, such as sulphate of magnesia or soda, Rocholle salts or phosphate of soda, should be at once administered, and repeated suC jiently often to keep the bowels relaxed, and in the intervals a mild febrifuge mixture may be prescribed. If much pain is present it may be relieved by phenacetine, Dover's powder, or small doses of morphine, or by the introduction of an anodyne into the vagina or rectum by means of a suppository. Warm vaginal douches should be administered every four to six hours, while the patient lies on her back upon a bed- bath. As the acute stages are subsiding the fomentations may be withdrawn, and the lower abdomen painted over with tincture of iodine. The douches are, however, to be continued, the temperature of the water being gradually elevated to the maximum degree which the patient can endure without much discomfort. The same treatment is applicable to purulent salpingitis at the outset, with the addition of intra-uterine douches every eight to twelve hours, if the os will permit the entrance of the instrument. In case that it will not, it may be advisable to dilate the cervix for that purpose. When severe peritoneal symptoms are present, vaginal and intra- uterine douches, and all manipulations likely to interfere with absolute rest, should be avoided until they have subsided. If there is dee'ded rise of temperature, especi- ally when intermittent, quinine, in five grain capsules, will act better than any other fe^ ifuge treatment. After the subsidence of the symptoms of an attack, prophylatic treatment should be continued, and every effort made to prevent the recurrence. For this purpose the patient should avoid all worry, excitement, fatigue, or over-work, resting, if possible, for a few hours every day. Antiseptic vaginal douches and mild counter-irritation over the abdomen should be continued, and during the menstrual period she should remain in bed. Drainage through the uterus should be encouraged and kept up, and for this 300 MEDICAL AND SURGICAL GYNECOLOGY. purpose the cervix should be dilated once or twice a week, and the uterine cavity touched over with some mild but efficient antise^ tic, such as a twenty-five-per-cent solution of ichthyol in glycerine. After each treatment the vaginal vault may be painted with tincture of iodine, a tampon of cotton aaturated with boro-glyceride placed against the cervix, and the vagina lightly packed with gauze. When the case has become chronic, and there is but little tenderness, and no signs of pus in the pelvis, electricity and pelvic massage have been praised, as favoring the absorption of the exudate, but in view of the difficulty there exists in making a diagnosis, such treat- ment must of necessity be surrounded by great dangers. If all therapeutic measures fail, after a sufficient delay recourse must be had to the radical operation of salpingo- oophorectomy. It is preferable to delay operation until the subsidence of an acute attack, but when the severity of the symptoms are such as to lead to the conviction that a purulent salpingitis is immediately endangering life, no delay should be made, but radical measures resorted to at once, for the removal of the adnexa and possibly of the uterus. Salpingo-oophorectomy is also indicated in inter- stitial salpingitis, if the patient suffers much pain, and has repeated attacks of pelvic peritonitis. Salpingo-oophorectomy. The appendages may be removed through the abdominal walls or through the vagina. 1. Abdominal sdlpingo-oophorectomy . The abdominal incision is made in the median line sufficiently large to allow the entrance of two fingers. The first and middle fingers are introduced into the abdominal cavity, the omentum and intestines pushed up, and the fundus of the uterus sought for. Passing the fingers outward along the tube to the ovary, they are both lifted up between the fingers through the abdominal wound. If there are adhesions they are cautiously separated, relying on the sense of DISEASES OF THE FALLOPIAN TUBES. 301 touch nlone. If the points of adhesions are difficult to overcome, they may be lifted into the wound and separated there, or it may be necessary to enlarge the incision, so as to make the whole pelvis accessible to the eyes and hands. When the tube and ovary are lifted up, a pedicle needle, threaded with a strong silk or catgut ligature, is pushed from the front backward through the broad ligament, a half to three quarters of an inch under the ovary. After removal of the needle, the ligature is brought up over the tube, close to the uterus, and tied tightly, after which the endp passed below the ovary, and sufficiently far away fron ,o allow for u pedicl , and again tied tightly. By this means the tube, ovary, and the included broad liga- ment are tied off, and may now be removed with a pair of scissors, taking care to take away all of the ovary, and as much as possible of the tube, while on the other hand sufficient pedicle should be left to prevent the ligature from slipping. After carefully walohing the stump to make certain that the vessels are securely tied, the surface may be smeared with a little iodoform, or aristol, the liga- ture cut short, and the pedicle allowed to sink down into its normal jjosition. As to the treatment of the appendages of the other side, there is much difference of opinion ; some authorities recommend their removal even if they are healthy, because they will very likely become affected later, while others recommend that an effort should be made to save them, even if found to be slightly diseased, particularly where offspring is much desired. If both appendages must be removed, it is rJmost as well to remove the uterus too. This organ is often the source of the infection, and besides, after the removal of the appendages it is useless, and may be the cause or source of a new infection. Besults. ^n a very large percentage the operation brings on the menopause at once, or after a few months. When menstruatio.i continues, it may be due to the in- 302 MEDICAL AND SURGICAL GYNJICOLOGY. complete removal of the appendages, to irritation of the stump, to disease of the uterus, or to the law of " persis- tence of habit." As a rule there is a discharge of blood for several days following operation, which is accounted for by the congestion caused by the ligatures. The sexual appetite may remain unchanged, increased, diminished, or may disappear altogether. In a considerable number of cases melancholia has developed. Even if the mental disturbance does not go so far as insanity, despondency and irritability are qui(;e frequently observed. Vaginal salpingo-oophorectomy presents the advan- tage that there is less shock, and less risk of causing a hernia, but it has the disadvantage that the field of operation is narrow and deep seated. When the diagnosis is uncertain, and when there are adhesions to intestine or omentum, it is much more difficult to cope with these difficulties through the vaginal route than by abdominal incision. The vagina is opened by anterior or posterior colpo- tomy, or by both, and if more room is necessary, an incision in the median line may be carried from the posterior transverse incision as far down as the bottom of Douglas' pouch. The fingers are gradually worked up until they pass through the peritoneum. Adhesions may be now carefully broken up, after which the appendages can be brought down and ligated. The vaginal wound may be ligated in cases where there has been no local infection, otherwise it is best to lightly fill the wound with iodoform gauze, and subsequently the vagina. Pyosalpinx signifies an accumulation of pus in a closed or cystic Fallopian tube. It is merely a tube, the walls of which show interstitial inflammation, with the abdominal opening obliterated by agglutination and firm adhesions of the fimbriae, and probably the uterine opening also obliterated by inflammatory thickening, or by torsion of the tube. The closure of the openings permits of the DISEASES OP THE FALLOPIAN TUBES. 308 retention of secretions and exudations within the tube, and, as a result, it undergoes enlargement and distension from the presence of its contents. The greatei enlarge- ments occur as the result of closure of both ends of the tube, the lessor are found in conjunction with a free uterine end, the contents of the tube having some oppor- tunity for escape into the uterus. The escape is either a constant leakage, or an intermittent discharge, brought on by direct contraction of the tube, or by indirect pressure. Pyosalpinx is generally unilateral, but may be bilateral. In the commonest form there is a general enlargement of the tube, club-shaped at the outer end, and tapering gradually towards the uterus, or more or less convoluted. The diameter of such tubes may reacli an inch or more. When there is an absence of constrictions, it may assume the appearance of a pear-shaped cyst, and attain the size of a normal uterus; rarely it may reach the dimensions of a foetal head. The pus contained in the sac is often mixed with blood, serum, or mucous, which accounts for such collection not presenting the active tendencies of collections of pure pus witnessed elsewhere. Collections of pus in a tube will often remain relatively quiescent for considerable periods of time, and may suffer partial absorption and inspissation, appearing ultimately as a pultaceous mass. The tendency, however, is for escape, the direction being most often along the canal to the uterus. Next in frequency, it tends to escape through the abdominal end of the tube, and least frequently by a combination of stretching and degeneration an opening may be made througa the tube wall. When the contents escape through the uterus, the tendency of the tube is to refill, and thus alternately emptying and refilling, the condition may exist for a long time, either ending in atrophy of the tube, or in permanent closure and the formation of a complete pus sac. Leakage from the abdominal end is not uncommon, each escape 304 MEDICAL AND SURGICAL GYNECOLOGY. being nccompnnied and followed, ns has already been stated, by the phenomena of local peritonitis proportionate to the amount and specific virulence of the fluid. Leakage through the wall of the tube is less common, but should it occur at the upper and posterior surface, the favorite situation, there would be discharge of the tube contents into the general peritoneal cavity, accompanied by all the dangers which pertain to such an accident. The opening may occur on the under surface of the tube, between the layers of the broad ligament, through which the pus reaches the subperitoneal cellular tissue, where its further incapsulation is largely provided for. Fortu- nately most cases of pyosalpinx beget such an amount of local peritonitis about them as will ensure strong pro- tecting peritoneal adhesions, and the occasional leakages only add to, and extend the adhesions, so that even though secondary foci of pus develop outside the tube, they are again held in check. It is in this way that pelvic abscesses are formed, and the further consideration of pus collections, originating in pyosalpinx, will be considered under that heading. Hydrosalpinx. Hydrosalpinx is a cystic enlargement of the tube, in which the general outlines and dimensions of the organ are in the main similar to those found in pyosalpinx. It is usually an advanced stage of pyo- salpinx, and represents a practical destruction of the tube, The walls are attenuated and may be so thin in places as to be translucent. The contents are serous, not puru- lent, and in many cases as limpid as water. It is found as a bilateral rather than a unilateral disease, and is rarely without the association of strong well organized adhesions. It is free from the aggressive action which characterizes pyosalpinx. It tends rather to quiescence, sometimes to intermittent discharges through the canal into the uterus, and ultimately to absorption and general atrophy, more particularly of the outer parts of the tubes. DISEASES OF THE FALLOPIAN TUBES. ilOo Haematosalpinx. Liko pyosalpinx, lianiintoHnlpinx Ims itH sont in tho ampulln, and hns similar dimoiisions and form. Leaving aside that form already mentioned when speaking of atresia of tho genital tract, there are two chief varieties. The first and most frequent is apoplexy of the tube, a condition which may occur in the coarse of a catarrhal inflammation, or during an irregular menstruation affected by fatigue, cold, or pelvic or uterine congestion. The tube is about the size of the middle finger, the contents fluid blood and retained in the tube by closure of the abdominal opening which has occurred at some prior inflammation. The lesion is usually only temporary, the blood is reabsorbed, and the symptoms gradually subside. The second variety represents a graver condition. There will probably be extreme dilatation of the tube, and an extremely thickened and infiltrated wall. On opening the tube it will be found filled with a syrupy, chocolate colored blood, or more often with a clearer liquid formed of a watery fluid and blood. Clots may form in layers on the walls, or in little fibrous masses lying free in the cavity. Various explanations have been offered as to their produc- tion. First, that there is originally disease of the inner surfaces of the tube, and from this a true hemorrhage occurs at each menstrual epoch. This blood coagulates, filling the ampulla. A second hemorrhage occurs with coagulation of its blood around tho original clot. This process is repeated time and again, until largo masses are produced, which in time soften in the centre, and lead to the conversion of the entire mass into a collection of blood debris. The second explanation is that it follows a pyosalpinx or hydrosalpinx, as tho result of traumatism, or twisting of tho pedicle or inner end of the tube. Tho third explanation presupposes a tubal pregnancy arrested in its development by the death of the foetus. 306 MEDICAL AND SURGICAL GYNECOLOGY. Tubo-ovarian abscess. When the inflnmmntory process extends to the peritoneum in cases of chronic salpingitis, it is sure to involve the ovary. The first effect will be thickening of the capsule, which in turn prevents the rupture of the ripe ovarian follicle. The tension pro- duced gives rise to considerable disturbance and pain, and, as the enlarged follicles cannot discharge their contents, it necessarily follows that an ovary which has long been the seat of peri-oophoritis will be largely converted into Fig. 94— Pyosalpinx and ovarian abscess. cystic spaces (cystic ovaritis), two or more of which may become confluent, and form a cyst the size of a walnut. As such p cyst enlarges, it not unfrequently comes in con- tact with a dilated pus-containing ampulla, and by mutual contact adhesions form and absorption takes place between their walls, and the cyst becoming infected, a tubo-ovarian abscess is the result. Atrophy of the tube may result from the destructive action of pelvic suppuration. After a partial atrophy of the walls by cystic degeneration, a rupture and discharge of the contents may be followed by cicatricial contraction and partial obliteration. Traces of mucous membrane and muscular fibre may remain, but the chief part consists DISEASES OF THE FALLOPIAN TUBES. )}07 of conuoctive tissue bo contracted as to rooemblo a fibrous cord. Symptoms. Tho clinical picture does not materially differ from those drawn of non-cystic salpingitis. Tlu^re are the same pains, and the same menstrual disorders. At times there may be a sudden flow of a certain purulent, serous, or bloody fluid following an attack of colicy pains, occurring at irregular intervals of a month or six months. Unless there is leakage, or rupture into the abdominal cavity, no marked constitutional symptoms may be present, and it is possible for a woman to carry about with her two sacs filled with pus, without any serious phenomena, or even seeming to suffer from their presence. Between the initial period of formation and the final period of inflam- mation of surrounding parts, and efforts at spontaneous evacuation, pyosalpinx passes through a torpid and latent phase, during which the rational symptoms seem to be exactly similar to those of chronic salpingitis, and the physical signs in no wise different from those of hydro- salpinx and hsematosalpinx. Two groups of symptoms are really characteristic; the pain which directs attention to the uterine appendages, and the local examination which results in the finding of a tumor at one or both sides of the uterus. Physical examination should be undertaken with the utmost care, as serious and even fatal accidents have been caused by too rough handling of a pyosalpinx. By bimanual exam- ination, a pear-shaped body can be made out, extending from the side of the uterus, and connected to it by a slender pedicle which can scarcely be reached. When the tumor is bilateral, it gives the sensation as if " a wallet had been thrown over the uterus, saddle-bag fashion." Fluctuation is rarely felt, but pain is always caused by the examination. Sometimes the tumor falls down into Douglas' pouch, giving in that region the sensation of the presence of an elastic or fluctuating globular mass, incor- 308 MEDICAL AND SURGICAL OYNiECOLOQY. porntod with th(i i)OHtorior Hurfnce of the utorus. It is UHimlly purulimt, and is at first frots but grndunlly bc^comos so ndluToiit to the surrounding parts tlmt it is trnns- formod into n voritnblo pelvic nbscess which cannot bo enucleated. Diagnosis. Appendicitis is distinguished by the high position of the exudate, by the seat of the pain being abdominal rather than pelvic, and radiating towards the umbilicus, rather than into the hips, or down the thighs. The attack is generally attended by disorders of the stomach or bowels, and with much greater tendency to nausea and vomiting, and there are usually absent those symptoms specially referable to the genital organs. Pyosalpinx is to be suspected, if the dilatation of the oviduct follow gonorrhcBal or puerperal infection, and if the tumor be closely adherent. Pyosalpinx is frequently, and hydrosalpinx usually double, while hjematosalpinx is unilateral. While the tumor is still movable it may be mistaken for a small ovarian cyst, and especially for an intra-ligamentous cyst. The latter however is soft, fills the ligament flush with the uterus, and is thus without a pedicle. A parovarian cyst is softer, and has no traceable connection with the uterus, and no adhesions. The differential diagnosis from tubal pregnancy is often difficult during the early months, but there will be the absence of those characteristic symptoms to be referred tr> later on. It may be mistaken for a '- dunculated intra- peritoneal fibroid, but a fibroid is ^' a, insensitive, and can easily be traced to the uterine wall, while the adnexa may possibly be palpated on either side. Treatment. As soon as the diagnosis of a cyst of the tube is established, salpingo-oophorectomy must be per- formed. As said before, operative interference should not be undertaken during an acute attack, but if it be of so serious a nature as to threaten general peritonitis, or if PELVIC INFLAMMATION. 30.) there bo (Ijiuger of rupture of the pyosnlpinx, thoughtH of delay muHt not be entertained, ns operative interference in the only way to Have the patient's life. CHAPTER XXVII. PELVIC INFLAMMATION. Much confusion has existed for a long time in the classitication and complete understanding of diffuse in- flammations of the pelvis, and, as a result, a variety of names has appeared in the literature of pelvic inflamma- tion, intended to represent the conditions which, under varying circumstances, seem predominant. The intimate relations existing between the Fallopian tubes, ovaries, peritoneum, cellular tissue, and lymphatics, compels an almost constant intermingling of the lesions of inflamma- tion affecting them, and consequently under the heading "pelvic inflammation," recent authorities are disposed to include all those inflammatory diseases which involve these structures, treating them as if a single disease. As hos already been pointed out, a pyosalpinx rarely exists except it is complicated by pelvic peritonitis, and in all probability by pelvic cellulitis, and the abscesses which form are usually the result of more advanced stages of those conditions. There are, however, two forms of inflammation occur- ring within the pelvis, which, from a clinical standpoint at least, deserve separate consideration, and the phrase "pelvic inflammation," as here used, is to bo understood to include the two affections, pelvic cellulitis and pelvic peritonitis. Inflammation of the several viscera contained in the female pelvis are described under their severol headings, and will only be referred to as far as they are concerned in the pathological processes that lead to the two diseases just named. 310 MEUU'AL AN'l) SUIUMCAL OYN^COLOOV. PELVK! CELLULITIS. Pelvic cellulitis, hIho known by tlu^ Hyiioiiyms para- mrfn'fis niid prri-nfrrinc phliu/mon, is an iaHammatiou of the pi^lvio connective tisHue. Such inflnmmation may be pfimdrji or scrouildrif, tliat is, it may originate in the connective tiwHue itself, or in one of the neighboring structures, and reach the connective tissue by extension. The primary form, or that which will now be con- sidered, is an acute infective disease, and differs in no respect from acute inflammation of the connective tissue in any otlier part of tlie body. Chronic pelvic cellulitis is always a secondary affection complicating inflammation of some other part. Etiology. Primary pelvic cellulitis is always a result of septic infection. Its most common source is the absorption of septic matter owing to laceration of the cervix uteri, or of the upper part of the vagina, during labor. Other sources of infection are the various surgical manipulations practised on the vagina and cervix. The lymphatics are the channels by which the poison is conveyed to the connective tissue, hence there is always a certain amount of lymphangitis associated with cellulitis. It is highly probable that the lymphatic glands are also generally implicated, particularly the lumbar which re- ceives the lymphatics from the broad ligament and body of the uterus, and the hyjjogastric or pelvic glands which roceive the lymphatics from the cervix and upper part of the vagina, and as such have been described as pelvic lyinplimufitis. Pelvic cellulitis occurs with or without formation of pus. In tlie latter case there is an exudation of coagulable lymijh with oedema into the tissue of the infected area, which at first produces increase of '^ulk without manifest alteration of consistence. Very soon the inflamed tissue becomes stiff and indurated, and, at a later stage, seems as PELVIC INFLAMMATION. 311 hard nn cartiln>^i\ Tliiw iiiHnmmatory cxiulntioti may gradually uiidorj^o absorption, and oviuitunlly diHappoar, or it may trrminato in wiippuration, with the formation of a p(>lvic! abHC(*H8. Usually thoro in a Hin^^ltt abHcoHH cavity, but ocoaHionally ntivural an* formod. Symptoms. Polvic cellulitis is often ushered in by a chill or rigor. In puerperal cases this usually occurs on the second or third day aft(>r dtlivery, but it may be later. In non-puerperal cases it seldom exceeds a day or two. The tempiTature rises, and the pulse becomes (quickened. Severe pain is peldom present, unless the inflammation extends to the neighboring peritoneum. When suppura- tion has occurred, the most marked symptom is progres- sive emaciation, associated with pallo •, or a peculiar sallowness of the skin. There is complete anorexia and the bowels are usually constipated, though occasionally there is diarrlioja. In the early stages, local examination does not give much information. After the lapse of several days, the exudation in the tissue of the affected area becomes densely hard. When the infection has occurred at the upper part of the vagina, or through the cervix, the latter loses its normal mobility, and the supra-vaginal ti-ssues on the affected side are tender, p.vd more or less hard and unyielding. It is seldom that both sides of the pelvis are uniformly affected. In the majority of cases the inflam- mation spreads laterally along the base of the broad ligament, and then passes toi ward to the tissues beneath the reflection of peritoneum on the anterior abdominal wall, and the induration produced there takes the form of a broad band lying along the upper border of the inner portion of Poupart's ligament. Sometimes the exudation spreads upward and outward from above Poupart's liga- ment into the iliac fo.ssa, interfering with the action of the psoas and iliacus muscles, and causing the patient to keep the thighs flexed. In some instances the inflamma- 312 MEDICAL AND SURGICAL GYNAECOLOGY. tion passes bnckwnrcl instead of forward, producing an exudation in the tissues of the utero-sacral ligament, in the tissues surrounding the rectum, and in those beneath the peritoneum lining the posterior pelvic wall. ^\' hen the body of the uterus is tlu^ starting point of the cellulitis, and the broad ligament the seat of the exudation, bimanual examination will reveal a hard, smooth, flattened, slightly movable tumor by the side of the uterus, and inseparable from it. Pelvic abscess. When a pelvic abscess forms, the situation of the abscess, and the position where it may be expected to point, will u ipend upon the direction in which the inflammatory exudation has extended. When the inflammation is seated in the tissues at the base of the broad ligament, and passes forward, forming an area of induration above Poupart's ligament, the presence of suppuration is manifested by oedema in the skin over the indurated area which pits on pressure; by the signs of deep seated fluctuation, and by the eventual pointing of the abscess a little above Poupart's ligament. When the inflammation extenc s backward, and suppuration occurs, the abscess is formed beneath the peritoneum covering the back of the pelvis, and, as free access is difficult, burrowin is almost inevitable. Extension into the iliac fossa and the loin is more particularly apt to take place when the posterior pelvic wall is the seat of an abscess, the abscess pointing either at the iliac crest or above it. Sometimes the pus leaves the pelvis by the sciatic notch, and follows the course of the gluteal vessels. In other instances it may make its appearance in ScarpaV *^riangle. Pelvic abscesses may, though very rarely, discharge them- selves into the rectum, vagina, or even the bladder. The usual time for an abscess to point is from the seventh to the twelfth week. Diagnosis. Pelvic cellulitis may bo mistaken for hoematoma of the broad ligament, or a fibroma of the PELVIC INFLAMMATION. 313 uterus. The history of the case, nnd the fibHonce of symp- toms of severe ilhiess will, as a rule, serve sufficiently to distinguish a luismatoma from an inflammatory condition. Hrematoma occurs suddenly, either from rupture of a pregnant tube, or of a varicose vein in the broad ligament. In either case the onset is usually marked by sudden pain and faintuess, and usually also by an attack of vomiting. In the case of rupture of a pregnant tube, one or two menstrual periods will have been missed, and attacks of pain will have occurred in the lower part of the abdomen, generally at one side, with slight irregular hemorrhages from the uterus. It must not be forgotten, however, that a h.'i3matoma may become infected and undergo suppura- tion, when the symptoms will be similar to those of pelvic abscess due to cellulitis. In regard Lo myoma, no great difficulty should arise, unless developed laterally between the layers of the broad ligament, and complicated by an attack of localized peritonitis. The mobility of the ".ervix, and the absence of pain and tenderness, as well as the absence of the constitutional symptoms attending cellulitis, should readily diagnose it from the latter condition. Prognosis. Except in those severe forms in which cellulitis forms only a part of a general septic process of the most acute and fatal type, the disease usually termi- nates in recovery. As soon as th- fever subsides the exudation begins to undergo absorption, and will have entirely disappeared in a few weeks. Should the fever not subside in the course of five or six weeks, suppuration has probably occurred, and the duration and progress of the illness will then largely depend on the direction ii \i the pus may take in its efforts to reach the surface. In the large majority of cases the abscess will point above Poupart's ligament, where it can be opened. These cases almost invariably do well. In the rarer cases, where suppuration occurs at the back of the pelvis, the pus is longer in reaching the surface, and is apt to burrow. 314 MEDICAL AND SUROICAL GYNJICOLOGY. Such cnHoa often Inst a long timo nnd are very trying upon tlio pntiont. Treatment. Romomboring that this diHoaso which pr()(hic(^H Huch wi(h> sprimd destruction, and ofton danger- ous and oviMi fatal results, has its origin in septic infection, the neces^:ity for strict asepsis, or surgical cleanliness, becomes fully apparent. If freedom from infection could be ensured to every parturient woman, and a similar free- dom extended to every woman who is submitted to vagiual examination and manipulation, pelvic cellulitis, as a primary affection, would entirely disappear. It is doubt- ful whether, when once an attack of pelvic cellulitis has been initiated, it is possible to modify to any great (^xt(^nt the course of the disease, hence strict care should be tak^^n not to do harm by meddlesonn^ interf(5rence or frequtnit examinations. The state of the bowels should receive the most careful attention, and a regular course of aperient medicine should be kept up. A mild febrifuge mixture, containing liquor ammonije acetatis, or citrate of potash, may be admin- istered. The tendency to emaciation calls for generous dietary, and the X)fttient's appetite should be tempted by every means available. When induration and pain are felt in the pelvis, hot fomentations kept in place by a bandage, or hot water bottles, should be applied to the lower abdomen. Vaginal douches of hot water should be administered frecpiently, after which a boro-glyceride tampon, or one saturattnl with a ten-per-cent. solution of ichthyol in glycerine may be inserted in the vaginal fornix. When there are evidences ot suppuration, ([uinine may be administered, and, if necessary, the system sup- ported by stimulants. The abscess should be opened as soon as fluctuation is detected, or there is the faintest indication of pointing, and treated on general principles. The point for incision, whether intra-vaginal or external, must depend largely uj)on the direction which the abscess PELVIC INFLAMMATION. 315 HoottiH to bo tiiking, and the dogroo of pointing in that direction. (^lironio prlvic oollulitiH doos not oxist an nn indopon- dont (Uhc^uho, or nn a sociuol to tlu^ Jicntc^ form, but it occurs occjiHioruvUy fiH a Hc^condary rosuit of purulent HalpingitiH. It oidy involves tlu^ parts immc^diati^ly contiguous to tlio intlanu>d structures, and never gives rise to the broad band of induration in the lower part of the abdomen so common in the primary affection. PELVIC PERITONITIS. Pelvic peritonitis, also known by the synonyms peri- mctrHis, peri-i^dlpiiuiitis, and pcri'-ooplioritis, is an in- flammation of that portion of the peritonc^um situated within the pelvis. It is much more common than pelvic cellulitis. In a large majority of cases, if not in all, it is an infective process, due either to the presence of micro- organism or to their chemical products. Etiology. Pelvic peritonitis, as now understood, probably never occurs otherwise tlum as a result or com- plication of some preexisting disease within the pelvis. Not infre(iuently, however, it is the first indication of the presence of such disease, for the symptoms of peritonitis are for the most part acute, and of a character to compel attention, whereas those of the original disease are often so slight as to be scarcely noticeable. Sdtpiiif/ifis (did its ('omplicdiions. In the vast majority of cases pelvic peritonitis is the result of inflammation of t'nC Fallopian tubes. The methods of infection of the p(4vic pi^ritoneum, by means of the tubes, and the effects produced, immediate and remote, have already boon con- sidered when speaking of salpingitis. New (jrowfliH. Peritonitis may result from twisting of the pedicle of an ovarian tumor, or by the presence of any new growth in the pelvis, and it is in this way in ordinary cystic disease adhesions are formed. 316 MEDICAL AND SURGICAL GYNAECOLOGY. SepticAvmid. When septic infection of a severe type follows abortion, parturition, or surgical manipulations, giving rise to diffuse septic infection of the pelvis, the pelvic peritoneum will also be involved. Pelvic cellulitis. Pelvic peritonitis may result from the spread of the inflammatory process from the pelvic connective tissue, more particularly when it is attemled by suppuration. Disease of the vermiform (ijypewlix is not to be for- gotten. Occasionally the appendix is found lying within the pelvis, and, when investigating a case of pelvic peritonitis, it is well to remember that it may arise from disease of that organ. Pathology. The earliest change produced in the peritoneum is hyperemia, with cloudy swelling of the endothelium. The membrane loses its normal, smooth, shiny appearance, and becomes dull, dry, and slightly roughened. Plastic lymph is then poured out on the surface, which leads to rapid formation of adhesions be- tween the adjacent surfaces. In addition to the lymph effused, there is also an eft'usion of serum which tends to accumulate, principally in Douglas' pouch, but it also tends to form collections of fluid in different parts of the pelvis, where spaces intervene between the adhesions. One of the earliest results of the adhesive process is to roof in the contents of the pelvis from that of the general peritoneum. The intra-i^eritoneal collections of serum are absorbed, but the adhesions formed continue for a long time, and many of them become permanent, with the result of producing more or less serious interference with the functions of the vise ^^a involved. When the disease causing the peritonitis is purulent, the peritonitis is also apt to be purulent, and as a result, instead of accumulations of serum amongst the adhesions, collections of pus are ' irmed — intra-peritoneal abscess. PELVIC INFLAMMATION. 317 Symptoms. An attack is characterized by pain in the lower part of the abdomen, sudden in the onset, and at first severe in character. There is rise of temperature, rapidity of pulse, and intestinal disturbance, indicated by vomiting and local or general distension. After the acute pain has subsided, movements of the body are painful, owing to the tenderness of the inflamed parts. There is usually constipation, and pain preceding defecation and during micturition. In subacute and chronic cases, pain in the back, and inability to undergo physical exertion, are the most common and may be the only symptoms, while trifling causes, such as slight over exertion or ex- posure to cold readily provoke localized acute attacks. Such recurrent attacks are especially apt to occur when the chronic pelvic peritonitis is kept alive by the presence of pelvic suppuration, and serves as a better guide to the diagnosis of pus in the pelvis than does the temperature. In course of time, patients become ill and emaciated, and entirely incapacitated for work of any kind, and may even become invalided. During an acute attack of pelvic peritonitis the patient lies on the back, usually with the knees drawn up. The lower part of the abdomen is extremely tender to the touch, and the walls over the area affected more or less rigid. On vaginal examination, the parts at this stage will be too sensitive to allow of a satisfactory investiga- tion. In there be any depression in the vaginal vault, it will be central and not lateral, owing to the filling up of Douglas' pouch. There may be tenderness and a sense of resistance on pressing the fingers upwards into one or both lateral fornicos, but it will not be possible to map out any definite swelling until the acute symptoms have subsided. After this has occurred, a careful bimanual examination will probably reveal an inflamed Fallopian tube as a fixed, irregular, tender, sausage-shaped swelling, and gradually increasing in size as it extends outwards 318 MEDICAL AND SURGICAL GYN/ECOLOGY. from tho uterine cornu. As the patient recovers from the immediate effects of the attack, the hardness of tho peritoneum gradually disappears, and tho outline of the adherent appendage more readily made out. Diagnosis. Pelvic cellulitis. Pelvic cellulitis is a much rarer disease than pelvic peritonitis. Its origin is exclusively septic, never gonoiTlioeal or tubercular, and is essentially a disease of the puerperium, or one following surgical manipulation. Cellulitis, when uncomplicated, is unattended by pain, or at any rate by severe pain. In both diseases there is swelling in the lateral regions of the pelvis, but in cellulitis the swelling is usually unilateral, smooth, uniform, attended with fixation of the vaginal vault, and of stony hardness. In peritonitis it is more apt to be bilateral than unilateral, and instead of being smooth and of uniform consistence, is irregular in outline and unequal in consistence. In cellulitis the cervix is apt to be surrounded by a hard thick collar, in which it is immovably set, whilst in peritonitis it is not present, and the impairment of mobility of the cervix is never so com- plete. In cellulitis the rectum will often be felt surrounded wholly, or partially, by a belt of exudation of ston; hard- ness, fixing the coats of the bowel at that pa.t, and narrowing the cavity of the canal. In peritonitis en- largement will be in Douglas' pouch, and will bo less hard, and will not affect the mobility of tho walls of the bowols to the same extent. When cellulitis has its seat in the broad ligament, bimanual examination will reveal a smooth, hard, flattened tumor by tho side of and continuous with the margin of the uterus. This tumor can be moved backward and forward within certain limits. The swelling caused by the inflamed and adherent appendages in pelvic peritonitis is, on the contrary, of irregular contour, and is not continuous with the uterus, but on a plane behind it, and quite fixed. PELVIC INFLAMMATION. 319 Pelvic ho'imttocele. The diagnosis will largely dopond upon tho clinical history. As pelvic hremntocele, in n majority of cases, is a complication of tubal pregnancy, there will usually be a history of early pregnancy, and of a sudden attack of pain accompanied by great faintness. The patient will have a blanched appearance, or that of shock. The effusion is at first fluid, but soon acquires a doughy consistence, and later becomes diminished in bulk and harder. Prognosis. The prognosis in pelvic peritonitis is much less favorable than in pelvic cellulitis. The mor- tality is higher, and the after effects in those who recover are apt to be much more troublesome. The damage done to the uterus, ovaries, and tubes during an attack fre- quently produces sterility. Displacements of the uterus are apt to follow, together with the symptoms induced by such conditions, and the normal action of the bowels are apt to be disturbed. Treatment. Preventative. Inasmuch as the large majority of non-purulent cases of pelvic peritonitis is duo to gonorrhoeal salpingitis, care should be taken to destroy gonorrhceal infection as soon as discovered, and before it has gone beyond the reach of local applications. Strict attention to surgical cleanliness in every form of manipulation will often prevent the occurrence of salpin- gitis, the forerunner of pelvic peritonitis. In those who have once been the subject of pelvic peritonitis, it is im- portant to avoid such causes as are likely to provoke a relapse, such as exposure to cold during the menstrual period, over exertion, prolonged standing, and inattention to the bowels. The medicnl treatment consists in very much tho same measures as those recommended for the relief of pelvic cellulitis. Pain being a most distressing symptom must be relieved by small doses of morphia, and the tendency to the formation of scybala prevented by the careful use 320 MEDICAL AND SURGICAL GY> ECOLOGY. of onomatn. Sliould tho stnto of tho pulso indicate it, stimulants in tho form of brandy or whiskey should bo given in defined and measured doses, and the effects care- fully watched. Tendency to collapse should bo mot by the application of hot water bottles, and by hypodermatic injections of strychnia. Surgicdl measures, when necessary, are best deferred until the acute symj^toms have subsided, and until an opportunity has been afforded of making a thorough bimanual examination and arriving at a correct diagnosis. If it is a first attack, and the symptoms such as to lead to the diagnosis of non-purulent inflammation of the appen- dages, operative interference should not for a moment be recommended. If, on the other hand, the patient has had several attacks previously, and the swelling has attained such dimensions as to make it fairly certain that pus is present, nothing but tho operative measures advised when speaking of salpingitis will be of any avail. CHAPTER XXVIII. DISEASES OF THE OVARIES. Malformations. One or both ovaries may be con- genitally absent but such a condition is very rare. When it does exist, it is generally only a part of a complete want of genital development manifested by the parts makiiig up the vulva, vagina, and uterus. More common than absence is rudimentary development, in which tho ovaries may or may not contain Graafian follicles. Tho gland itself may bo of nearly normal size and in a normal situation, but the gland contents, the Graafian follicles and ovules may be absent. Such conditions may be found in connection with a normal uterus, but most commonly thoy are found associated with arrest of DISEASES <»F THE OVARIES- DISPLACEMENTS. li'll (lovolopinont of timt orgnii. A dinf^aosis in suoli cnsos is extremely difficult, but the condition may be presumed when the ovnries cannot be palpated bimanually, com- bined with want of development in the other genital organs, with absence of the usual signs of the menstrual crisis, and with lack of general constitutional vigor and development. The ovaries of now-born children may be twice their normal size, a condition which may be due to uniform enlargement of its constituent parts, or to fo)tal inflamma- tion resulting in a preponderance of connective tissue, and a partial or total disappearance of the (xraafian follicles. Accessory ovaries immediately joining the normal ovary, and included usually within the same peritoneal investment, have been found. The ovary may likewise be constricted so that it consists of twoi)ractically independent parts. A true supernumerary ovary, far removed in station from its fellow, is extremely rare. DISPLACEMENTS. Congenital displacements of the ovaries are very rare. In the early embryo they are situated, like the testicles, in close relation with the kidneys, but soon after birth they are found to occupy a position in the true pelvis. Only in extremely rare instances have ovaries been found re- tained in their original relations with the kidneys. Congenital inguinal hernia of the ovary is also rare, but when it occurs, it is generally due to deficient develop- ment of the round ligament, by which the ovary, tube, and sometimes one horn of the uterus, are pulled through the canal of Nuck. There are usually no symptoms until menstruation sets in, when there may be much disturbance of that function. The only treatment consists in extirpa- tion. Acquired displacements of the ovaries are not un- common. Any influence which increases their weight, or 322 MEDICAL AND SURGICAL GYNiECOLOOY. drnwH upon thorn directly, or nets upon tliom by trnction, mny cauKo tlicm to lonvo their position, nnd Honu^times to such an extent ns to pnss out of the pelvis in the form of n hernia. Cduscs. Displacement of the ovaries may be brought about by any causes which will increase their weight; such as inrtnmmatiou, hypertrophy, or cystic degeneration. They may be a(!ted upon by contraction of effused lymph resulting from pelvic peritonitis, or by contraction of the ovarian ligaments drawing them out of place. It may be brought about by displacements of the uterus, more par- ticularly retroversion and retroflexion, or by insufficient support from below, especially when it is the outcome of a weakened or ruptured perineum. Displacements may bo subdivided into intra-pelvic and extra-pelvic, according to whether the ovary is found within, or outside the pelvis. Intra-pelvic displacement, or prolapse of the ovary, is a common disease, and one of considerable practical importance. When the ovary becomes displaced it sinks backward, downward, and inward, first upon the retro- ovarian shelves, and next into Douglas' pouch, describing in its descent an arc of a circle. Symptoms. The symptoms will vary according to the causes which have induced the displacement, and to the possibility of its return to its normal position. Ovaries prolapsed behind the uterus manifest themselves by more or less severe, or constant pain in the lower part of the back, usually referred to the sacral or rectal region, and intensified by the passage of hardened feces or by the act of coition. There is a further sensation of dragging or bearing down, and when the ovary is adherent these symptoms are usually aggravated. The (iimjnosis is usually made by vaginal examination. Tile prolapsed ovary can readily be touched in its abnor- mal position, giving a peculiar sensation of faintness and DISEASES OP THE OVARIES— DISPLACEMENTS. 323 nauHOft wluui prossod upon. It mi^ht bi^ iniHtakeii for a swollon tube, but tho latter is more sausa^e-HhapiHl. A small podunoulatod fibroid in hardor and not stMisitive, while scybala may be indented or crushed without much pain, and may be removed by enemata or cathartics. Tr<'((tm<'iit. The treatment consists in replacing the ovary, if it is movable, by digital manipulation, or by posture in the genu-pectoral position, and, after replace- ment, its return to the pelvic cavity prevented by some suitable support, suoh as a Thomas' retroflexion pessary, or astringent balls or tampons of cotton packed behind the cervix. If a retro-displacement of the uterus exists, the reposition of that organ, together with the ovaries, and its retention by a suitable pessary will usually suffice. If the ovary is adherent it will be necessary first to endeavor to stretch and break up adhesions. This may be done by pelvic massage, and by packing the posterior fornix of the vagina, while in the genu-pectoral position, with cotton balls, the first few inserted being i opregnated with boro- glycoride,or a ten-per-cent solution rf ichthyol in glycerine. If these measures fail recourse may be had to radical methods. If there are no adhesions and the uterus is freely movable, Alexander's operation may be performed; if otherwise coeliotomy .must be undertaken in order that the adhesions may be broken up, after which the uterus should be retained in place by ventral fixation. Extra-pelvic displacement, or hernia of the ovary. The ovary p.ay pass through the same openings as other herniee, bxc all but two forms are exceedingly rare. Irufuinal. The passage of the ovary into or through the inguinal canal can only occur when the tube and infundibulo-peivic ligament are unusually relaxed and elongated. When such a condition exists hernia may be produced by a fall or similar violence, and the ovary, in its abnormal place, may become inflamed, or undergo cystic or cancerous degeneration. 324 MEDICAL AND 8UROICAL OYN JICOLOOY. Tlic ilidj/iiosla niny bc^ nmdi^ by tlu^ prc^Hoiicc^ of a tumor ill tho inj^uinul region oorrtiHpoiidiiig in Hhnpi^ to that of tho ovary, nnd producing a peculiar sickening Honsation when prcHHcd ui)on. Bimanual examination revoals abHcnco of tho ovary from the pelvis and tilting of the corresponding uti-rine cornu to that side, while backward and forward movement of the uterus causes the tumor to move. The hernia may be reduced by taxis, and held back by the application of a suitable truss. Herniotomy may be necessary to relieve the imprisoned ovary, and wIumi per- formed may be followed up by a radical operation to securer permanent results, or by extirpation of the ovary if it is found to be diseased. Criit'id. The ovary may make its way through the crural ring into the crural canal. Tho same symptoms and treatment are applicable in this variety as in the former. HYPER-EMIA AND H<EMATOMA. Hyperaemia of the ovaries occurs to a considerable extent during each menstrual period, and often just pre- vious to, and during coition, but should liyperiBmia be kept up for any length of time, or is frequently repeated, it will result in persistent dilatation of tho vessels, and some serous effusion into the stroma; and in more stwore cases hemorrhage into the Graafian follicles may take place. The hemorrhage may bo confined to one follicle, or it may occur in many. When thoro are many follicles aifooted, rupture of their septa may take place, producing luTBmato —1. of a size varying from a pea to a walnut, or even Ir ^ iiage into the stroma is apt to assume the form o jrous minute extravasations. The blood may bo cc /lotely absorbed, or remain as a coagulnm, or as a mass of tarry fiuid. The fluid part may be absorbed altogether, leaving a granular pigment, or tho solid parts DISEASES OF THE OVAKIES—HYI'ER^MIA. .'^25 limy b(> abHorbinl, ho that only a cyHt HlU'd vvitli Hcrouw tluid riMnaiiis, or Huppuration may Hot in. An oxti^nHive litMiiorrha^o may causo rupturo of tlio ovary, and the bh)od pouring into tho poritonoal cavity or ponotrating between the two layerH of the broad ligament, will form a htematocelo. Kfiolof/jf. It may be due to anything which will produce venouH staaiH, such as maHturbation, venereal excesses, uterine displacements, and sedentery habits, or it may arise from causes which produce a disordered condition of the blood, such as severe burns, phosphorus poisoning, scurvy, typhoid fever, or septicsemia. Hijmi)f()ms. A patient affected with hypeniMnia of the ovary is likely to suffer from menorrhagia, and accom- panying it there will bo pain in the region of the ovaries am extending down the ti ighs- and sometimes neuralgia of t. e breasts. Hemorrhage into the ovary may take place without giving rise to any symptoms. If the collection is large, it causes severe pain, and even nausea and vomit- ing, and on examination the ovary will bo found enlarged. Hyperemia and luematoma may be diagnosed, if, in a healthy person, one or both ovaries suddenly become enlarged and tender without fever. In those who have been affected with blood dissolution, luematoma may be inferred if the patient is seized with ovarian pain, and a movable tumor can be felt in the pel. "?. Tvcdtmenf, In hyperemia, rest in bed is demanded; but to be complete, physiological rest must bo secured as well. The general health should be improved, suitable tonics administered, and the bowels properly regu- lated. Some form of local treatment for tho purpose of reducing general hyperremia should be instituted, such as occasional counter-irritation over tho lower abdomen by moons of tincture of iodine or blisters, by hot vaginal douches, and by the use of ichthyol or boro-glycoride tampons. Later the patient may be allowed to return to 326 MEDICAL AN1» SURGICAL GYNECOLOGY. out door oxorciso, still keeping up the local and general treatment, but rest in bed must be insisted upon during each menstrual period. Should an acute attack occur at any time, the patient sliould at once be put to bed, an ice bag placed over the hypogastric region, and a dose of morphia administered to relieve the pain. If the ovaries have suffered in structure, the result ot prolonged hypera^mia, or from repeated attacks, they should be removed. OOPHORITIS. Oophoritis, or inflammation of the ovary may be either acute or chronic. ;ute oophoritis. The inflammation may bogin on the surface, 'pcri-oophorifis; in the anterior, intcrstitidl oophoritis; in the follicles, /o///c«/(^ir oophoritis; or in the stroma, intor-follicnl<ir oophoritis. As a rule both organs are involved. Etiology. Acute oophoritis is infrequently found out.jide the puerperal state. It may, however, be ca\ised by hyperemia and luBmatomaj or by any of the causes mentioned as liable to produce that condition; or by a sudden suppression of the menstrual flow. It may follow minor operations, such as the use ol' the .sound, incision of the cervix, or trachelorrhaphy. From proximity of the ovary to the abdominal end of the tube, inflammation of the latter necessitates an almost constant implication of the ovary, peri-oophoritis being here the first form pre- sented. Oophoritis may however occur quite indepen- dently of salpingitis. The lymphatics leading from the ovary connect in the meshes of the broad ligament with those coming from the upper part of the uterus, and it is thus easy for pathogenic germs to reach the ovary through those channels and infect them, without the presence of salpingitis. Interstitial oophoritis is the form here pre- sented. DISEASES OF THE OVARIES— OOPHORITIS. 1327 Wlietlior the initial lesion begins within or without the organ, the results will generally be the same, for by trans- mission through the lymphatics outside implication will extend to the interior, and inside implication to the exterior. When the disease begi- •? as a peri-oophoritis the surface will be found covered th a serous, plastic, or purulent exudation, in accordance with the grade of in- flammatory action present. The ovary wJl be enlarged, and in the plastic and serous types, the cortex will be more or less infiltrated with small round cells, similar to inflam- matory processes in other organs. If the type of inflam- mation be purulent, pus cells will predominate. Beginning as an interstitial process, the same elements pervade the organ, the predominance of the simpler inflammatory elements, or those indicative of suppuration, being gov- erned by the presence or absence of septic elements. The Graafian follicles in all cases suffer changes kindred to those going on around them. There is turbidity of the liquor folliculi, with softening and disintegration of the membrana granulosa, and the ovum. Course. In the absence of purulent infiltration, it may terminate in resolution, or in connective tissue sclerosis leading to atrophy, or the follicles may be con- verted into cysts, the cva and the membrana granulosa undergoing fatty degeneration. Purulent infiltrati(m leads tO the development of abscesses, coalescence of which may convert the ovary into a complete pun sac, nothing remaining but the tunica albuginea. These pus sacs may become encysted, but the rule is, a continuance of suppur- ation until the pus makes its way through the tunic, when the course will be similar to escape of pus from the tube. Sytnpfoms. Often the symptoms are masked by those of the disease which produced it. The ovarian region will be the seat of a burning pain radiating down to the knee, and tc the bladder and rectutn, and occasionally there will be reflex pain in the breast, and not infrequently 328 MEDICAL AND SURGICAL GYNECOLOGY. nausea and vomiting. By bimanual examination it is possible to feel the ovary enlarged and exceedingly tender to the touch. When an ovarian abscess has formed, it will give rise to symptoms similar to the formation of pus elsewhere, and when felt, a sensation of fluctuation may possibly be made out. It is seldom possible to make a certain diagnosis. An inflamed tube or a pyosalpinx is sausage-shaped when palpated, an inflamed ovary or ovarian abscess is round. Pelvic abscess is situated lower down and is absolutely immovable. h'ui. 95.— Ovary with many dropsical follicles CLeopold). Ti'catntciif. The patient must be kept quiet in bed, with an ice bag over the affected side, and the bowels kept relaxed by means of saline aperients. Pain is to be combated by means of morphia in some form. If the symptoms point to tlie presence of pus, it is to bo removed either by abdominal or vaginal oophorectomy. Chronic oophoritis represents certain changes brought about in the ovary the result of repeated attacks of congestion or of acute inflammation, or it may be a chronic process from the beginning. The common changes which occur are (itrophy and cystic dc(jeneration. Atrophy DISEASES OF THE DVARIES— OOPHORITIS. 32*.) is most mnrkocl in conjunction witli adliosions. which, by compn^ssin^ the ovnry, iiicreuso tiic sch'rotic changes in'Uiccd by the acute interstitial form. The whole organ may bo converted into a small mass of connective tissue, with almost entire disappearance of distinct formation. In the ci/sh'c form the albuginea is thickened, and the organ filled with cysts intermixed with comparatively normal follicles. The cysts are transformed follicles with thickened walls surrounded by indurated tissue, the ova and membrana granulosa having undergoiu* fatty degener- ation and absorption, leaving merely limpid Huid. In other cases the cysts may contain a gelatinous or colloid material. Some of these cysts may be so large as to involve the whole ovary. Kfiolofji/. Chronic oophoritis is much more common than the acute form, and is often the result of, or follows acute iuHammation. A displaced ovary strongly pro- dispo.ses to it. It is most frequently due to puerperal or gonorrhceal infection, while venereal excesses, masturba- tion, the abuse of alcohol, and syphilis are strong factors in its production. Sipfiptoms. The symptoms are often masked by sur- rounding inflammation. The patient compLiins of pain in one iliac fossa, or if both ovaries are affected, as is often the case, in both fossjB, the pain often extending to the rectum, bladder, hips, and down to the knees. The pain is increased at the approach of the menstrual period and during coitus, especially if the ovary is prolapsed. Stand- ing or walking for even a short time gives great fatigue. Menstruation is often irregular and profuse, but in the atrophic form there may be amenorrhcea. Leucorrhooa is a common accompaniment, and often the digestive and nervous system suffer to a greater or less extent. ( )n ex- amination it is extremely difficult to say whether a mass felt through the roof of the vagina is an ovary or tube. 330 MEDICAL AND SURGICAL GYNiECOLOGY. Sometimes the enlarged and prolapsed ovary can be made out by its globular form and extreme tenderness. Treatment. The management of chronic oophoritis coincides in most respects with that described for chronic salpingitis, and when the case has been seen early, treat- ment may be of great benefit, but when degenerative changes have taken place to any marked extent, it will be readily understood that no immediate benefit can be de- rived. A displaced ovary, or retroverted uterus should be restored to its normal position and retained there. Hot vaginal douches and medicated tampons often give much relief from pain, and absorption of inflammatory material may be promoted by painting the vaginal vault with tinc- ture of iodine. Notwithstanding local and general treat- ment, carried out methodically and persistently, in many cases nothing short of an operation for the removal of the diseased structures will be of benefit, and should be recommended before the patient's health commences to break down from the continued strain on the nervous system. CHAPTER XXIX. DISEASES OF THE OVARIES CONTINUED. NEOPLASMS. From a histogenitic point of view tumors of the ovaries have been divided into neoplasms of connective tissue origin, and epithelial neoplasms. The first group, desmoid tumors, includes fihromata, sarcomata, and myxomata, all of rare occurrence. The second group, epithelial tumors, includes cystomata, carcinomata or alveolar epitheliomata, and adenomata or mucoid epithe- liomata. For convenience of study, and from a clinical stand- point, they are most conveniently divided into cystic and solid growths. The cystic tumors include simple, pro- DISEASES OF THE OVARIES— NEOPLASMS. 331 liferatiiu/, (Irrnioid, and hrodd ligiimont cysfs. The solid tumors nre Jihroniatd, sarcoimita, and aircinomdta, all comparativoly rare. OYSTS OF THE OVARY. Cysts may originate in any part of the tubo-ovarinn structure; in tlio cortical, medullary, or parenchymatous structure of the ovary; in its inferior border or hilura; in the structures between the tube and ovary in which are found the remains of the Wolffian body, known as the organ of Rosenmuller, or the parovarian structure; or in the hydatid of Morgani, the obliterated remains of the canal of Gartner. Cysts may also develop in the folds of the broad ligament, and then are known as brodd li(j<i- mciit r/y.s'/.s. The cysts may bo nnilociildr with limpid contents, or muUiloculdr with varying contents, some clear and limpid, others thick and viscid, or discolored with admixture of blood. From an anatomical standpoint it is important to dis- tinguish cystic growths according to the size which they attain. Some of moderate dimensions may be well toler- ated or give rise to troubles, which, though painful, do not threaten existence. Others, on the contrary, increase in size with the greatest rapidity from the moment their development has been started. Small cysts may be subdivided into: — 1. Snidll rosidudl cysts coming from Morgani's hydatid, or the horizontal canal of the parovarium. 2. Follivnldr. 3. Cysis of tlic corpus lutcum. 4. Tubo-ovdvian cysts. Large cysts may be subdivided into:— 1, Gldndnldr prolifcrdting. 2. Popillary prolifci'dtiny. 3. Dermoid. 4. Parovdridn. 1. Small residual cysts. In uterine fibromata and ovarian tumors at the start, there are found either on the broad ligament or on the tubes, small transparent vesicles, but are of no surgical interest. They are of three kinds: — 332 MEDICAL AND SURGICAL GYNECOLOGY. i. Cjl^t of the hijddtid of Mor(jffni. Attached to the fimbrinted end of the Fnllopian tube there is generally found a cyst varying from the size of a pea to that of a cherry, transparent, and covered with a single layer of endothelium. This hydatid is the remains of the extremity of the canal of MuUer. ii. Siipra-fnhdl ri/sf is no larger than the preceding and has the same appearance and structure. It is probably a micro-cyst of the broad ligament which has s'ipped under the serous membrane, and worked its way up to this unusual position. iii. MicA'o-cysts of the broad lujament. Some of the.^e are suspended from Rosenmuller's organ, and some are Fig. 96. — niagr.ini of the structures in and adjacent to the broad ligament. (I)oraii.) t. Framework of the parenchyma of the ovary, seat of a simple or glandular nuiltilucular cyst, I a. 2. Tissue of hilum, with, 3, papillomatous cyst. 4. Hroad ligament cyst. 5. A similar cyst al>ove tube, but not connected with it. 6. A similar cyst developed close to 7, ovarian fimliri;p of tube. 8. The hydatid of Morgagni. 9. Cyst developed from the horizontal tube of parovarium ; cysts 4, 5, 6 and 8 are always lined internally with a single layer of epithelium. 10. The parovarium. 11. A small cyst developed from a vertical tube. 12. The duct of Gartner, often persists in the adult as a fibrous cord. 13. Tract of that duct in the uterine wall. free and of undetermined origin. Only those which originate from the vertical tubes of the parovarium have ciliated epithelium, and are likely to subsequently develop into papillary growths. DISEASES OF THE OVARIES — NEOPLASMS. 333 2. Follicular cysts. Hydrops of the Granfinn folliolos wns long coiisidorod the only or chief onuse of Inrgo ovarian cysts. From failure to rupture owing to some morbid cause, particularly inflammation of the appendages, the follicles may form cysts from the size of a hemp seed to that of a walnut (cystic ovaritis). There may be ex- ceptionally an agglomeration of several of these sacs, causing the ovary to become as large as the fist or a foetal head (Rokitansl^ifs tumor). 3. Cysts of the corpus luteum. This cyst, when first described, was believed to be a corpus luteum of pregnancy transformed into a cyst, but microscopical examination of the walls will show the bud-like papilla* characteristic of the corpus luteum. The recognition of this prevents their being confused with follicular cysts, or with suppurative ovaritis. They are generally no larger than a walnut, but cases have been described in which they have attained the size of an orange. 4. Tubo-ovarian cysts. The presence of an ovarian cyst not infrequently results in the formation of a tubo- ovarian cyst tlirough its proximity to a distended tube. A dilated follicle or small cyst may rupture into a dis- tended tube with which it is in contact and adherent, and form one sac. They do not usually attain to a large size. The uterine opening of the Fallopian tube may remain pervious and as the fluid increases it passes into the uterus. Large cysts. Proliferating cysts are also called myxoid cystomata in opposition to dermoid cystomata, because their inner surface resembles a mucous membrane. The term "proliferating" has been given them because they produce new cysts or papillary growths from their inner surface. There are two varieties, (fUmdnUir and ptipllUo'jj. 1, Proliferating glandular cystoma has a wall com- posed of the same structures as found in follicular cysts and similar external epithelium, but the internal epithe- 334 MEDICAL AND SURGICAL GYNyGCOLOGY. Hum undergoes a remarkable proliferation which results in the development of gland-liko growths. This epithe- lium is polymorphous, but the long columnar is the predominant variety. It is stratified and forms pouches, which are at first placed regularly side by side, and are about the same size, but in consequence of the continued proliferation they become closed, thus forming a secondary cyst in the wall of the primary cyst. When the secondary cyst is formed, the same process of proliferation is re- peated, so that continually one generation of cysts is Fio. 97. — Small imillilociilar cyst. (Museuiu of the College of Physicians and Surgeons.) formed in tlio wall of another. With the production of new cavities, a r(>duction in their number takes place by the absorption of the partition which separates them. By this continued proliferation of epithelial cells, formation of new cysts, and absorption of their walls, very large tumors are formed, in which, as a rule, one cyst pre- dominates, with a greater or smaller number of secondary cysts in its wall. These cysts are therefore always multi- locular from a pathological standpoint, although they may be considered unilocular from a surgical one. This variety of tumor is by far the most common, and may reach an enormous size. The outer layer of the wall corresponds to the albuginea, is smooth and dense in texture, and pearly- grey or white in color. The inner layer furnishes the DISEASES OP THE OVARIES — NEOPLASMS. 335 connective tissue, and together with the epithelium enters into the composition of the secondary cysts. It is of a reddish color, slightly uneven, and velvety like the inside of the stomach. From the outer layer may grow small excrescences covered with short columnar epithelium. As a rule they have a pedicle. Contents. In very small new-formed cysts, the tumor may be one solid mass of cells, but as a rule the contents '.1^ ''©* :°:9©r^ *' Fig. g8. — Microscopic examination of fluid from ovarian tumors. A. Epithelial cells. H. Oil globules. C. Fine granular matter. D. Crystals of cholesterin. E. Gran- ular cell. F. Blood corpuscles. G. H. Pus cells, i. Inflammatory globule", of Gluge. become more fluid as the cysts grow. The fluid in com- mon ovarian cysts is of a grey, yellow, or brown color. It may be limpid as pure water, or filled with solid bodies as not even to be translucent. Usually it is more or less viscid. Its specific gravity will therefore vary much, but 336 MEDICAL AND SURGICAL OYNiECOLOQY. itrt reaction is always alkaline. Generally ovarian fluid does not coagulate Hpontaneously, but by bein^ boiled the oont(>nts are more or less completely turned into a solid mass. It possesses a remarkable degree of resistance to decomposition, formed elements being sometimes preserved in it for weeks. As a rule, ovarian fluid is full of a variety of formed elements, red blood corpuscles, epithelial cells, nuclei, pigment granules, finely granular globular bodies like lymph corpuscles or colorless blood corpuscles, pus corpuscles, spindle-shaped cells, and crystals of cholesterin and of indican. 2. Proliferating papillary cystoma is not nearly so common as the glandular, being found in only one out of fit;. 99.— Papillomatous ovarian cyst. (Museum of the College of I'lij'sicians anil Surgeons.) ten ovariotomies, nor does it acquire such large dimen- sions. Tlu^y contain a comparatively small number of secondary cysts. From their inside spring dendritic or cauliflower-shaped growths, called papilloraata, whicli may entirely fill the secondary cyst in which they grow and break tlirough its walls into a neighboring cyst; or they may perforate the wall of the primary cyst and cover the outside of the ovary and neighboring parts. They may DISEASES OP THE OVARIES— NEOPLASMS. iiiil ovon pcnotrato tho uterus, blnddor, roctum, or otlu^r visoorn, HO ns to form oiui masH with tlicm. The paijilla' nm^(> in ni/iO from that of a poa to that of a small oraiij^fc. They aro Hossih^ or pt'(hinoulatt'(l, and may bo white, dark red. or black. Tho interior of a papillary cyst is usually lined with ciliated epithelium, and the contained fluid not viscid or colloid, but of more watery consistency. This kind of tumor is often bilateral, and its development is much slower than that of the glandular variety. It is ()ft(Mi nr- compani(^d by ascites. Mixed proliferating cysts. In one and the same cyst some cavities may be of the glantlular typ(% others of tlie papillary, indi(^ating that there is no radical diU'ercMice between the two varieties, the glandular variety being built up of the epithelial walls which center into the forma- tion of the ovaries, the papillary from its conn(>ctive tissue mainly. Origin of proliferating cysts. There is still a con- siderable divt^rsity of opinion in regard to tln^ origin of these cysts. Microscopical examination has shown that both the glandular and tlu^ papillary variety may devi^lop from a (Jrnatian follicle. Another sources may be the germinal epithelium, which in some ovaries, even of adults, forms pouches extending into the stroma of the ovary. Some claim that the papillary cystomata are de- veloped from remnants of the Wolffian body growing into the ovary from the hilum. The source of the glandular variety is by some thought to be a degeneration of the tunica intima of the arteries in the ovary. 3. Dermoid cysts. These cysts vary greatly from any already described. The internal surface is covered with a nu'.mbrane which looks like skin and has a similar struc- ture. Upon the surface of the derma are papilk-e, anil hairs are inserted into hair follicles occasionally provided with a sebac(H)Us gland. The hairs, whether inv or im- planted, are long, and tawny in color, agglutinated 338 MEDICAL AND SURGICAL QYNJJCOLOOY. to^(>tlu«r by Hc^mcoous mnttor nnd somotimos rolK^d into littlo ImiIIh. Sebum n^Hembliii^ tlu< V(*rnix caH'Hwa, jMirtly tillH tlu' cavity, and ofton forniH Hmall iHolatod niaHHCH. It is sonu'timivs oily in consiHtoncy, and contains many (4)itliolial c(*11m, (rholi^Hterin crystals, and fatty acids. T(H<th and bones have been found in these cysts. The bones are in- sorted in tlie wall, and are more or loss covered by the der- mic layer. Thoyare irregular in shape, usually flat, and formed of compact tissue. Cartilage is sometimes present in small patches. Tho teeth project into tho cavity, and are often loosely in- serted into alveoli lormed of bony de- bris. As many as one hundred teeth have been found in one cyst. Unstriped muscle fibres have been found in the Fn;. loo.— Dermoid cyst, sliowiiiK pl.ites of bones and dermic laVOr. CaSOS large qll.^ntities of long tawny hair. are quoted where striated muscle fibre and nerves distributed to the teeth, have been found. A most remarkable case is reported where the cyst, besides skin, hair, and teeth, contained a body which resembled an eye, with a species of convex cornea, and epithelium like that of the retina. There was DISEASES OP THE OVARIES— NEOPLASMS. I}|}U also n mucous momhrano similar to that of tl'.^ intostiii^H and stomach, and cncophah)id ucrvi^ substatico. Oviijin. Tho (lucstiou of the origin of ('crmoid cysts is one of tho most obscure points in gtMiend pathoh)gy. Various theories have been put forth. It has been ascribed to extra-uterine pregnancy, to diptogenesis by fojtal inclusion, and to parthenogenesis duo to a pro- liferation of germinating epithelial cells. The theory of impaction, accortling to Pozzi, is, on the whole, the most satisfactory. According to this view, during intra-uterino existonee certain portions of the blastoderm become im- pacted by pressure within the tissues, and develop there later, giving rise to an irregular formation of the normal tissues. The outer surface of a dermoid cyst is, as a rule, of a dull gray, or greenish color, with orange or ochre colored patches. They are small, or of nu'dium si/e, rarely exceeding in size an adult head. Commoidy but one ovary is affected, but two or three cysts may develop in tlu^ same ovary. A dermoid cyst may form adhesions and ruptuni into another organ, or on the surface of tlu^ body. Tf it opcMis into tlu^ bladder, hairs may be elimiimted with thi^ uriiu>i. A dermoid cyst in one ovary may be combined with a proliferating myxoid cystoma in the other. Etiology of ovarian cysts. Little or nothing is known about the circumstances which cause their development. They are met with at all ages. Simple cysts have been found in the ovary at birth. Even in young chikln^n multilocular cystomata have been found. Commonly however, they appear during the period of greatest sexual activity. Single women are proportionately more liable to the disease than married. 4. Broad ligament cysts. Broad ligament, or, as they are sometimes called, parovarian cysts, are net in reality cysts of tho ovary, being anatomically s(^parate from it, but are best described in connection with tho latter, being surgically and clinically closely connected to 340 MEDICAL AND SURGICAL GYNAECOLOGY. thorn. Broad lignmoiit cysts nro much rarer thnii ovarian cysts, and. as a rule, arc monocystic. Commonly they do not oxcood the size of a pregnant uterus at six months gestation, out exceptionally they may become enormous. As a rule, the wall is so thin as to be translucent, but in exceptional cases, the cyst may look like a uterine growth, on account of the thick layer of involuntary muscle fibres. The wall is composed of peri- toneum, a layer of connective tissue con- taining muscle fibres, and but few blood vessels, the absence of which gives it its white color. Its internal surface is smooth, or wrinkled, but has no glandular formation, and is covered \\ith a single layer of epithe- lium. The fluid is normally watery, nearly colorless, and alkaline or neutral. It does not coagulate spontaneously, nor to any extent by heat before adding an acid. Papillary and dermoid cysts may also develop in t le broad liga- ment. As a rule cysts of the broad ligam >nt are sessile, but sometimes the ligament forms a pedicle. They are found during the period of sexual maturity; they grow very slowly, do not impair the health, and give rise to no symptoms except such as are produced by their bulk. The pedicle. Whatever the origin of ovarian cysts, ther(^ is one important point in their surgical history, the presence or absence of a pedicle. Ovarian cysts as a rule rise up into the abdomen, and are connected with the uterus by means of a pedicle. In some cases the develop- [•'k;. ioi.- Unilocul.ir cyst. (Museum of the College of Pliysici.ans aiu\ Surgeons.) DISEASES OF THE OVAKIES — NEOPLASMS. Ml merit tnkes plncc downwnrd, so thnt the cyst is sitiiiitod betwecni the layers of the broad ligament, more or less close up to the uterus, and accordingly has no pedicle. The pedicle may be long or short, thick or thin, broad or narrow. It always contains the ligament of the ovary, and part of the broad ligament, and, as the tumor grows, the Fallopian tube is drawn in so as to form part of it, and is as a rule both elongated and thickened. The arteries may become as large as the radial and the veins the size of the finger. Besides these structures, lymphatics, nerves, in- voluntary muscle fibres and connective tissue, all forming a bundle covered by a peritoneal sheath, enter into its formation. Accidents and complications. 1. Torsion of the pedicle. When the pedicle is long and thin, the tumor from some cause may rotate on its axis. Sudden torsion may lead to gangrene and fatal peritonitis. If it develops slowly, it will cause rodema and hypencmia of the wall, hemorrhage into the wall and cavity, or suppuration. If the torsion continues the whole pedicle may be se\ red. Torsion of the pedicle may involve the intestine and cause its occlusion; on the other hand it may effect a cure, by causing atrophy from diminished blood supply. 2. Adhesions. So long as the wall is covered with its epithelium it slides freely over the surfaces with which it comes in contact, but when the epitheihim is rubbed off", or covered by inflammatory exudation, adhesions to the surrounding structures or organs are easily fornunl. 3. Ascites. An accumulation of ascitic fiuid some- times accompanies an ovarian cyst, especially the prolifer- ating papillary variety. 4. Ilemorrhcuje. Blood, arising from erosion of the vessels, ulceration of the walls, or torsion of the pedicle, may be poured into the cystic cavity, imparting to the fluid a dark red or bn-iwn color. 842 MEDICAL AND SURGICAL GYNECOLOGY. Suppuration. Tlie wall of a cyHt may booomo inflamed and tlio contonts chanj^od to pus. Tho suppuration may W" duo to torsion of tlio pedicle, to puncture of the cyst, or to puerperal infection. (). liupfnrc. The cyst may rupture and pour its con- tents into the abdominal cavity, when the fluid, if unirrita- ting, may become absorbed. Bloody, ichorous, or purulent fluid, and the contents of dermoid cysts cause more or less violent peritonitis, and very likely death. Rupture may also occur into the intestine, stomach, vagina, bladder, or Falloijian tube, or through the abdominal wall, especially at the umbilicus. 7. C((lrijic(iti(>n (ind ossifwatioii may take place to such proportions that the whole tumor may be changed into a hard shell. 8. Cdtircrnus (Icf/rnrrafiou. Proliferating glandular cystoraata and dermoid cysts may become malignant and implicate neighboring organs, and with the formation of metastatic deposits elsewhere. Symptoms. The onset is characterized by vague dis- turbances which do not differ from those described under uterine symptoms. They are at first reflex troubles due to congestion and stretching of the appendages, later come symptoms due to pressure on the rectum and bladder, but the latter are often absent. Following these occurs the period of tumefaction, when the abdomen becomes more or less distended, and the general health aff'ected. Two stages in the development of cystic tumors can bo recogni'/AMl. In the first stage the tumor is small, is hiddiui in the pelvis, and recognized only by bimanual palpation. In the second stage the tumor has become abdominal and may be felt through the walls. Pelvic sUujc. As Boon as the tumor has attained three or four times the size of a normal ovary, it falls into Douglas' cul-de-.sac. Bimanual examination will determine its presence, and its situation and connections, as well as its DISEASES OF THE OVARIES— NEOPLASMS. 343 ovarian nature. It is usually hard, bocause of the small size and great tension of the capsule. When it has a well defined pedicle it is very movable. When included in the broad ligament it seems to be one with the uterus, but careful examination will reveal a slight groove between them. Tumors limited to the size of the fist or ftwtal head will probably remain permanently in the pelvis, otherwise they will ascend into the abdominal cavity. A Inlom hud shu/c. By palpation a well defined spherical tumor is felt above and laterally, but leas marked below. Irregular shape or protuberances generally indicate a polycystic tumor. Fluctuation may be felt, the degree deixniding upon the size of the tumor and the elasticity and thickness of its walls. Percussion over the tumor gives dulness. Bimanual palpation reveals the uterus anteverted, lying just in front of the pubes, and pushed slightly to the opposite side from the cyst. The cervix is drawn upward and not easily within reach. In some cases the uterus ir.ay be pushed downward, and in cysts of the broad ligament it may be pushed completely to one side. The sound .sometimes will show decided elongation of the uterine cavity. When the cysts have grown to a large size the abdom- inal walls will be thinned out, fluctuation will be more readily made out, while towards tht? s'do^ solid masses are often found. Percussion elicits flatness over an irregular spherical area, convex above, and separated from the region of hepatic dulness by a zone of resonance. Pressure on the aorta and crural arteries may cause vascular souflles. Menstrual disorders are rather rare. Menorrhagia is often very extensive in follicular cysts of the ovary. Sterility is an unavoidable result when both ovaries are att'ected, but a unilateral ovarian cyst sometimes compli- cates pregnancy. Pressure upon the bladder often pro- duces incontinence of urine, and upon the rectum constipation. When the tumor reaches very high in the JUJ: MEUICAL AND SURGICAL GYNAECOLOGY. jibdomon, tlio inovemonts of tho dinplira^m tnny be st^riously ombarmssod, onusing dyspiuun aiul cyanoHis. Sooner or later tlie gt^ioral health becomes rapidly im- l)aired, caused by (ioinpression of the various portifjus of the digestive apparatus, joined with a reflex dyspepsia observed in the course of all utero-ovarian diseases. Com- pression of the ureters, though it may not for a long time cause albumenuria, does cause serious uropoietic disturb- ances, and adds to the malnutrition of the system. Pres- sure upon other organs, causing pain and sleeplessness, act in the same way by adding to the general enfeeblement. 'Vhen combined these conditions produce an appearance of ill health and distress to which Spencer Wells has given the name " fascies ovariana." Pro(/no!-fis. "When ovarian tumors," writes Spencer Wells, "attain such a size that the general health is affected, the length of life granted to the patient will probably not exceed two years, and these two years usually consist of serious trouble, even of torture and- despair," However, in some rare cases, the course of the disease may be very slow. Unilocular broad ligament cysts may rupture into the peritoneum several times in succession, with quite a long respite after each rupture. On the other hand, proliferous cyst"), after remaining quiescent for a long time, may suddenly take a rapid course. An absolute or relative spontaneous cure is not an impossibility. Intra-peritoneal rupture often brings about the cure of broad ligament cysts. Gradual torsion of the pedicle may, exceptionally, cause atrophy. Death is the ordinary result of cystic development, unless there be surgical interference. Marasmus, peritonitis, and embolus are the three causes of death. Ascites, although not necessarily fatal, is an unfavorable occurrence. Papillary cysts tend towards malignancy, and wluni so diagnosc^d, should always make the prognosis very guardinl. (ilandular cysts may also undergo cancerous degeneration. DISEASES OF THE OVARIES — NEOPLASMS. 345 Oortnlu clinical symptoms, indicated by sudden develop- ment of n tumor which has already existed for some time, rapid emaciation and cachexia, multiple adhesions, especially in the pelvis, redema of the lower limbs and abdominal walls out of all proportion to the size of the tumor and the amount of ascites present, leave no doubt in such cases. Diagnosis. 1. In the pelvic stage. In the early stages of ovarian cysts, it is difficult to distinguish them from other tumors situated by the side of the uterus. A sessile cyst of the broad ligament might be simulated by a ccUulifis or saljnngitis, but a remembrance of the previous symptoms, and the course of the disease, will prevent error. A small pelvic hfematocele shows fluctua- tion at first, but does not give tlie sensation of an en- capsuled tumor, while the manner of its appearance is entirely different. K.t'tra-ii ferine pregnancy in tlie beginning has few distinctive symptoms, except those of amenorrluea and congestion of the genital mucous membrane. Later it is characterized by special signs which will be referred to in a subsecpient chapter. Retrojlexion of the gravid nterus will be suspected when the signs of early pregnancy are present. 2. In the abdominal stage. Pregnancy. Error in such a case is a very serious one, and is mo' *^ likely to be committed when there is hydramnios, for then it is diffi- cult to palpate the fcBtus or hear the fojtal heart sounds. It must not be forgotten that amenorrhcua, swelling of tlie breasts, and imaginative sensations of fcutal movements, produced by borborygmus, may exist in a case of ovarian tumor. The diagnosis will be settled only by the rercep- tion of f(Dtal movement, the hearing of the heart sounds, the identification of foetal parts, contraction of tht^ gravid uterus, ballottement, and toward the end of pregnancy en- gagement of the fttital parts. 340 MEDICAL AND SURGICAL GYNAECOLOGY. Ascites. Ascites mny simulate a large cyst. In effusion of fluid within the pelvic cavity, the abdomen is more bpread out, less acuminated, and on percussion flat- ness is found in the dependent portions, and tympanites on the uppermost surface of the dome. In a position of lateral decubitus, the fluid gravitates to the side and iliac fossa, while the tympanitic note appears on the opposite side, where it did not previously exist. This displacement of the fluid is very characteristic. In cases where ascites has rapidly developed in connection with an ovarian Fig. 102. — The sh.ided portion shows the are.i of dulness. A. Ascites. B. Ovarian tumor. tumor, much difficulty may be experienced in making a diagnosis, but the rapid increase in the size of the abdomen, oedema of the lower limbs, decline of the general health, and the absence of a previously existent tu.nor, will assist in making a correct diagnosis. Another sign to be looked for is mobility of the uterus, which is present in ascites and absent in large cysts. Finally the condition of the heart and liver should not be overlooked, disease of either of which often gives rise to ascites. ^uhcrcnldv and cancerous peritonitis. In the first named there will be signs of intestinal or pulmonary DISEASES OF THE OVARIES —NEOPLASMS. 'Ml tuberculosis, and irregularities in the siuipe of the abdomen duo to nieteorism interfered with by adhesions. In th(^ case of cancer there will be tiie presence of irreguh'ir masses in the mesentery and neighboring parts, togetln^r with rapid cachexia. Puncture may be of service in establishing a tliagnosis, but at the present day it is usually omitted. Even when done with the greatest precaution it is by no means a harmless operation. It may bo followed by (effusion of tiuid into the abdominal cavity and fatal peritonitis; or by suppuration of the cyst; or by grave lunnorrhage from wounding a blood vessel in tli'' abdominal wall; or an o^ i^rlying portion of intestine may be punc- tured. If the tumor be of the papillary form, there may be escape of vegetations into the abdominal cavity, and conse(|Ucuit infection of the peritoneum. If none of these accidents happen, the puncture is apt to set up in- tlammatory adhesions, which, if extensive, or of long stand- ing, may complicate the removal of the tumor subsequently. Uterine Jihroids. Uterine fibroids, particularly fibro- cystic ones, may simulate ovarian cystomata, but a careful examination under an anjcsthetic, takiui in consideration with the history and symptoms of fibroids, will generally make the diagnosis easy. H(vm<itometr(i may be recognized by its situation and special etiology. Vesicdl distension has been the source of numberless errors, but may be avoided by the employment of a catheter before proceeding to examine. Renul tumors, hydronephrosis, and hyddtidiform ei/sfs have also given rise to mistakes. In such cases the diagnosis may be made by ascertaining whether the tumor is fixed in the hypochondrium, and free inferiorly, per- mitting the hand to be passed beneath it quite far above the pubes; and also by ascertaining whether the intes- tines, especially the colon, are interposed between the tumor and the abdominal wall. Tumors of the liver, 348 MEDICAL AND SURGICAL GYNECOLOGY. spleen, mesentery, omentum, and echinococcus, may also give rise to error, which sometimes can only to bo cleared up by coeliotomy. Tumors of the abdominal wall, phantom tumors, tympanites associated with partial contraction of the abdominal muscles, or superabundance of fat in any particular spot, may give rise to difficulty in making a diagnosis, particularly in hysterical patients, but the difficulty may be overcome by examination under an an.nesthetic. Treatment. It is scarcely necessary at the present day to reiterate the statement made by all writers, that there is only one form of treatment for ovarian cysts, and that is extirpation. McdiciiKil treatment. Electrolytic puncture, injections of iodine and other astringents into the cyst are now regarded as malpractice. It is only a few years since it was the frequent practice to tap the cyst several times before its removal, a proceeding which has been aban- doned by all who recognize its dangers. There may be circumstances under which it may be impossible to per- form ovariotomy on account of the objections of the patient or of the friends; or where the presence of cancer, extreme weakness, or grave vLsceral complications would render an operation inevitably fatal. In such cases tap- ping may be resorted to, to relieve immediate symptoms. OVARIOTOMY. Ephraim McDowell, of Kentucky, was the first to do an ovariotomy for ovarian cyst, in 180^). The pedicle was left in the abdomen, and a cure followed. Subsequent to this there were isolated cases of bold operations which found no imitators. In America, in 1844, W. L. Altlee commenced a remarkable series of operations which, in 1871, reached the number of two hundred and forty six. Ovariotomy can be said to have been thoroughly estab- lished in America after the year 1865. In England, DISEASES OF THE OVARIES — NEOPLASJIS. M\) bi^twooii 1852 niul 185(), Bnkor Brown oporatod iiiiio timcH. In tho yenr 1858 commoncod the remnrknblo cnrcor of Spcucor Wells, nud which wns kept up nlinoat to the time of his death, when he had well passed the thousand. The next prominent figure in ovariotomy is tliat of Thomas Keith, of Edinburgh, who performed his first operation in 1,862. On the Continent, the names of Koeberle, Schroeder, Billroth, Martin, and others, are honorably associated with the operation. The introduction of antisepsis into the field of surgery introduced a new phase of existence for the operation. Ovariotomy has now passed from the hands of a few eminent specialists into those of surgeons all over the civilized world. In every capital, city, or town, there are surgeons who, with honor to their art and credit to themselves, successfully perform the operation which, half a century ago, was condemned by the leaders of surgery as being little removed from murder. The operation. The patient having been prepared according to the general directions given in an early chapter, she is placed upon the back on the operating table. The incision is made in the middle line, between the pubes and the umbilicus, after the manner already described. On reaching the peritoneum it will be found to vary in thickness. It may be thinned by distension, or thickened by constant irritation or inflammation. When there has been much inflammation, the peritoneum may be a thick highly vascular tissue, which bleeds freely on division. The incision is made in that structure long enough to admit of the extraction of the collapsed and empty cyst without using force. If the tumor is unusually large, or the adhesions abundant or very dense, it may be subsequently enlarged to suit the conditions present. Emptying and delivery of the cyst. Whatever be the condition prefcent, it is always best to begin by emptying the cyst, and the best mode in the large majority of cases is by tapping. For a cyst of small size Wells' small cyst .*}50 MEDldAL AND SURGICAL OYN^ECOLOdY, trocar, nnd for n Inr^o ono Tnit's iuHtrunumt with blunt conical point, may bo used. To prcvont tlio t\scapc of Huid at the side of the trocar, a flat sponj^o wrapped around the point of introduction will suffice. After the trocar has entered the cyst cavity and the walls become fiaccid, large forceps are mad(^ to grasp the cyst wall and pull it steadily but gently out of the wound, keeping the pnrii^tes of the tumor in easy contact with the abdominal parietes. A flat sponge placed between the cyst and tlu^ parietes may be useful in preventing the escape of fluid into the abdominal cavity. Secondary cysts may b(* emptied without removing the cannula from the main (!yst. but whiles this is boing done, tlu^ flngiTs inside the abdomini should make certain that the trocar is not pushed through the main cyst wall. As the cyst is withdrawn the trocar opening is pulled ovt^r the edge of the wound, and as soon as it is clear of the abdominal opening, a fold of the (!yst wall above and below is caught in strong for- ceps. The trocar is now removed, and if the sac has not been emptied sufficnently for its total withdrawal, it may be incised betwet'n forceps, permitting the cyst contents to run down into the ovariotomy pad. Adhesions. If, after emptying the cyst as compU^tely as possible, adhesions prevent its biding delivered, the im- pcjrtant step of separating them is to be begun. For separating very soft, tine, and recent adhesions, a sjjonge may be used, the adherent structure being, so to speak, sponged away from the tumor. Adhesions of firmer con- sistency may be dealt with in various ways. If compara- tively recent they may be peeled off with the fingers. If the adhesions are old, fibrous, and thick, they may be sur- rounded by ligatures and divided. During the separation of adhesions the walls of any of the hollow viscera may be torn. Such laceration must of course be immediately closed by suitable sutures. If at any point the connection to the bowel or bladder is so intimate that complete separ- DISEASES OF THE OVARIES— NEOPLASMS. H51 ntion Houms dnnj^erouH to the integrity of the orjjjau, thou a thin layer of the ndhorent portion of the cyst wnil must be cut off and left behind. Tfcdtmt'ut of the pvtUclc. The pedicle has been sub- jected to almost every conceivable surgical treatment. " It has been tied (Mitire, tied in sections, been twisted oft', burnt off, crushed off, cut S([uaro off. cut off' in Haps, left inside, left outside, and has been made to slough oft'." — (Bland Sutton.) The extra-peritoneal treatment by the clamp is now permanently abolished, and needs no description. The silk ligature is now almost universally used for securing the pedicle, although strong coarse catgut is used by some Fig. 103. — Ligation of pedicle in three sections. surgeons. After fully exposing the pedicle, and estimating its size and the position of the blood vessels, a pedicle needle, threaded with stout silk, is passed through the centre, taking care to avoid all vessels. After dividing the silk into two equal parts, the needle is unthreaded and withdrawn. Each division of the ligature, after interlocking it with the other, is tied over its own half of the pedicle, and then returned and tied over the opposite half. 352 MKDUIAL AND 8lIR(4It!AL «YNiK(!OL()<»Y. WIhmi tho ixnliclo in vory brond it mny nuiuiro li^nt.ion ill MoctioiiH. TliiH mny bo dono by puHHiu^ tlu* pi'diclt^ iuhhHo, annod with tin oxtra lon^ nilk li^iituro, tlirou^h tho pedioh) ono third distnut from tlio mnr^iii. Tho loop i!\U8 formed in cnught on ono tiii^or und tlio iuhkUo Htill throudod withdrawn, and rooutorod midway botwooa tho last point of ontrancii and tlio oppoHito margin. Tlio podicUo neodUi in again withdrawn and th(^ loo^w arranged HO that thoy will bo of oqual hingth. Tho ligature in divided at tho loops, and after interlocking one with the other, each ligature is separately tied so as to include its own section. The ends of the outer ligatures may be reversed and tied around tho opposite sides of tho pedicle. A favorite method for so- curing tho pedicle is that known I'Ki. io4.-staffordshire knot, as tho "Staffordshire knot." The pedicle noodle, armed with a silk ligature, is passed through the pedicle and then with- drawn, so as to leave a loop on tho distal side. This loop is then drawn over the tumor, and one of the free ends drawn through it, so that one end is above while the other is under tho retracted loop. Both ends being seized in tho hand, they are drawn through tho pedicle until com- plete constriction is made. The pedicle secured, it may now bo divided at a distance from the ligature sufficient to prevent it slipping, and the stump allowed to drop back into tho pelvic cavity. The peritoneal cavity, if necessary, is to bo carefully cleansed, taking care not to overdo it. A sponge on a holder is left in contact with tho stump of tho pedicle until the parietal sutures are introduced, after which it may bo withdrawn, and if it indicates that no hemorrhage is going on, the abdominal wound can be closed. Accidents durhu) operation. Mishaps, such as the escape of fluid into the cavity, hemorrhage, or injury to DISEASES OF THE OVARIES -NEOPLASMS. 352} tlu^ viHC(^ni, may occur during tlu^ most. Himplt^ ovnriotoiuios, and tlu^y nro eHptH'-ially fro(iuciit in dilHcult cnsos. It is nocoHHiiry tlu^n^foro for ovory surgoon, to \w suo(H^HHful, to bo nbhs promptly and (>fHci(mtly, to deal with hucIi acuiidiuits, and without such knowUHlge no surgoon shouUl undcrtako an ovariotomy. Broad ligament cysts, as a ruhi, grow away from the ligament, pushing aside the ovary and tube, and o-^ca- sionally tht^y exhibit a well marked pedicle. Sometimes, however, they may grown downward, widely separating the layers of the broad ligament, and stretching out the tube and ovary over their walls. Adhesions are rare, but spon- taneous rupturt^ is not infrequent. These cysts wen^ onco r(Mnoved by tapping or aspiration, and their innocuous luiture and slowness to rt^till are great inducements to use that kind of treatment, but since it has been discovered that some of them are papillary growths, and the radical operation in most cases easy and safe, extirpation is pre- ferred. Thiur removal, when there is a pedicle, is to be a<;complish('(l the same as in ovarian tumors. In some rare cases, when the cyst grows between tlie layers of the broad ligament, removal may be attended with considerable difficulty. Here there is no pedicle, and the base of the cyst lies deep in the pelvis. The growth in these cases must be dissected out between the layers of the ligament. Beginning on the side next the uterus the jieritoneal investment is opened, and the wall of the cyst exposed. The finger pushed into the cellular tissue separates the cyst from the ligament, bleeding vessels being caught up by forceps. Step by step the process is continued until the cyst is completely enucleated from its bed. The two flaps representing the layers of the broad ligament may, according as seems best at the time, bo left untouched, or united by suturing; or after ligation in section, its upper portion may be cut .way and the peritoneal structures turned in and sutured. 354 MEDICAL AND SURGICAL GYNECOLOGY. Incomplete operations. Tlio presence of Hrm general ndhesious of nu intrn-lignnieiitous cyst which will not permit of its being enucleated without extreme shock and loss of blood, or the sudden collapse of the patient in the middle of the operation, may determine the surgeon to ccmclude it without total removal, or as rapidly as possible. In such cases the cyst may be emptied, and after beiii^; drawn up into the wound, as much of the sac as possible may be excised, and the remaining portion sutured in the lower angle of the wound and drained by gauze pnc';iiig. The method of .- raining by an openiiig through the vagina presents many advantages, especially in the c;ase of sup- puratii\g cysts firml)' adherent to the floor of the pelvis. SOLID TUMORS OF THE OVARY. Under this heading is included Jihroma, sdrcorna, and cjn'th: lioma or ctu'ciuoiiui. Fibroma. Fibroids of the ovary are rare. They do not form circumscribed new growths like flbroids cf the uterus, but seem rather to be a kind of fibroid degener- ation of the organ, and so uniformly hypertrophied that its shape and relations are not .xltored. As a usual thing they are small, not larg(^r than a hen's egg or an orange, but they may n^ach largCi proportions. They are hard in ct)usistency and have a mammillaied surface. They usually have a pedicle, and are free from adhesions be- cause of the .ascites which they produce. They may become cystic, due to dilatation of the lymph spaces in tlie connective tissue — the so called (/codes— and filled with a coagulable serous fluid. Siimj)f<)ms. The symptom which usually first attracts notice is ascites, caused by the excessive mobility of the tumor. When this symptom is absent, the tumor may escf^pe notice, or may accidentally be discovered by ptteiiiion being drawn . i the patient, owing to menstrual disturbances. li is alraost impossible to diagnose it from DISEASES OF THE OVARIES— NEOPLASMS. 355 i 1' ;. a pedu ^ulntod fibroid of tho uterus. Tlie trontmont con- sists in its removal by vaginal or abdominal hysterectomy. Sarcoma. This neoplasm is of rare occurrence. It may be primary, or it may develop secondarily in an ovarian cystoma, and is often bilateral. It forms a pink tumor, ranging in size from that of a smjdl orange to that of an adult head. It is globular or oval, has a smooth ii, surface, and of varying consistency according to structure. ji Spindle-celled sarcoma is the most common variety, but round celled and mixed celled sarcomata are also found. fi From a clinical point of view <^hese tumors are of great malignauviy, and the symptom^: are ihose of a rapidly developing malignant tumor. Ascites . .. ^ i is always present and cachexia rapidly , ^(^j^^ '^^C^^'^ ^ appears, features which distinguish it 0f^^ ^<^B>^\k -- [ from fibroma. ^"^T^^, ,^ f Epithelioma or carcinoma. If '^^^JfcTv^^^^ ® secondary cancerous degiMieration of ^^^l^^'^ ** ''^ ^■^ cysts is excluded, primary cancer of ^i^r^-^^^v^ the ovary is very rare. It may affect the young as well as the old, and is '''"=• i"5- Spin.iie-ceiie,i s.-»r- •' '^ coma of the ov.iry. apt to be bilateral. Two principal anatomical forms are described; one, a diffuse infiltratifui of the ovary, originating in the (epithelium of the follieU'.s of Pfiuger's ducts; the other a superficial !li>velo[)ment from germ epithelium. In the former, the ovary retains its shape fo^^^ a long time, with the exception that its surface becomes nodular. It may attain the size of an adult head, and as it increases in size the pedicle and broad ligam nt become infiltrat(>d. In the latter variety a dendritic growth appears on the surface of the ovary, whieli, in the later stage cannot be distinguished from papilloma of the ovary. Ascitic fli. 'd, possibly tinged with blood, is character- istic of this disease, and the other symptoms will be similar to those of sarcoma. The diagnosis is based upon ..<!»> i ■i/.^ :'■? 356 MEDICAL AND SUROICAL GYNECOLOGY. tho blo(Hl tinged ascites, infiltrntion of tho broad ligament, upon the existence of nodules about the rocto-uteri)io cul-de-sai-. and upon the rapidly appearing cachexia. When seen early, tho treatment consists of performing oophorectomy; later the treatment can only be palliative. CHAPTER XXX. ECTOPIC GESTATION. By this term is generally understood development of the impregnated ovum outside the normal uterine cavity. No entirely satisfactory conclusions have yet been reached regarding the cause of this form of preg- nancy. The chief difficulty lies in the fact that it has not yet been determined at what point of the female genital tract normal impregnation of the ovum takes place, and until this question is settled, the primary question, whether extra-uterine fcBtation is an abnormal ectopic impiegnation, or is simply a detained impregnated ovum, must remain unanswered. Etiuluiji). It is claimed by many that the seat of coalescence of the male and female elements is normally in the Fallopian tubes, and if such be admitted, it can readily be seen how a variety of causes m _, operate to detain the ovum in the tube. The most frequer . condi- tions named as tending to bring about ectopic gesf.ition. are : — Adhesions of the ovaries and tubes, the rt suit jf peri-salpingitis; loss of ciliated epithelium; ttoxioii of ^he tubes; dilatations and diverticula; constrictions from in- flammatory changes; and polypi of the tube, closing its lumen like a ball valve. Uiitil recently it was the common belief that the ovum might, after fecundation, develop primarily in tho tube, within a Graafian follicle, or in the peritoneal cavity. Modern research, and the advantages for observation which early cceliotomy has given in such ECTOPIC GESTATION. 357 cases, hnve chnngocl to a considerable extent the views once held. At the present time the weight of opinion leans towards accepting two primary forms of ectopic gestation, the tubal and ovarian, although niany able writers assert that all ectopic gestations are originally tubal. C](iss{Jic((fion. Ectopic gestation may be divided into 2)rini((rij and scvondary forms. The primary form may be thus classified: — id, Tubo-uterine or interstitial. 6. Isthmial. c. Ampullar. 2. Ovarfan In tubal pregnancy when the fertilized ovum vlevelops out near the fimbriated extremity it is called (impulhir; when at the inner portion of the tube it is called isthmUd; and when in that part of the tube which traverses the uterine walls, it is designated interstitial or tuho-uterine. Tlie secondary forms of ectopic gestation are derived from the primary. The tubo-uterine or interstitial may rux)ture into the uterus and be followed immediately by expulsion of the fijutus, or it may go on to full term and be delivered in the natural way. It is more likely, how- ever, to rupture into the abdominal cavity, or into the broad ligament. In the isthmial form, the rupture occurs into the abdominal cavity, giving rise to a secondary abdominal pregnancy; or into the broad ligament, forming extra-peritoneal broad ligament pregnancy. The ampullar form of tubal pregnancy gives rise to secondary tubo- ovarian. abdominal, or broad ligament pregnancy. The ovarian form gives rise to tubo-ovarian, or abdominal pregnancy. The secondary forms thus derived from the primary may be classified as follows: — (I. Uterine. 1. Interstitial. { h. Broad ligament, e. Abdominal. 358 MEDICAL AND SURGICAL GYN-ECOLOGY. a. Tubo-ovariaii. 2. Ampullnr. \ h. Abdominal. ii. latlitnial. i. Ovarian. Broad ligament. (1: Abdominal. I). Broad ligamont. (I. Abdominal. b. Tubo-ovarian. Tubal pregnancy. In the first week after fecundation the tube begins to thicken, which is mostly due to ex- cessive vascularization, and not, as in the case of the pregnant uterus, to any great increase in its tissue elements. As pregnancy progresses, the wall of the tube becomes thinnod and stretched, until in some cases it appears as a thin transparent membrane, composed only of an attenu- ated stratum of muscle covered with peritoneum. The dovelopraeat of the fcetal membranes is the same as in intra-uteriiie pregnancy, except that the placenta is largely foital in its origin. During the first four to six weeks, the abdotninal ostium of the tube becomes hermetically sealed. Ui'til the foetal membranes are well formed, the chorionic villi have but a feeble hold upon their points of attach- ment, and may be easily separated. Should this occur during the first two or three weeks of pregnancy, it will probably give rise to no serious di.scomfort, but, if later, the accompanying hemorrhage may cause rupture of the tube, followed by death of the motlier. If the ovum continues to grow, the point of attachment of the placenta is one of great importance to the mother. If it is implanted in the upper wall of the tube, she is in constant peril, for rupture means almost certain death from hemorrhage, there being no counter-pressure to con- trol the lacerated or detached placenta. If implanted on the floor of the tube the chances for rupture are decreased, and when rupture occurs the dangers from hemorrhage are diminished, owing to the placenta being pushed downward against the resisting pelvic floor. Occasionally the ovum ECTOPIC tlESTATlON. 359 is lightly attnclu'd in tlu^ finipulUir oxtnMiiity of the tubo, aiul is extruded into tlio nbdoiniiml caxity without rupture of the tubal wall. This extrusion is known as fiilxti abortion. Tubo-uterine, or interstitial gestation. In this typo the museular fibres of the uterus undc^r^othe same changes as in normal pregnancy. Rupture is almost inevitable, but it does not occur as early as in the tubal form. The foetus occasionally escapes into the uterus, to be at once expelled, or to go on to full term. Rupture however in this case most frequently occurs into the abdominal cavity, followed by profuse hemorrhage, wliich u.sually terminates the patient's life. Rupture of the sac. Tlie time at which this may occur depends uj)on the location of the placenta, and to a certain extent upon the attachment. In tubal pregnancy, primary rupture occurs usually between the second and four- teenth weeks. The rupture is owing to thinning of the walls of the tube beyond their limits of elasticity by hemorrhage or by gradual enlargement of the embryo; or it may occur as the result of traumatism. If the patient survives the primary rupture, the foetus may continue to develop, either burrowing down between the layers of the broad ligament or extending upward into the peritoneal cavity. The blood, if poured out into the peritoneal cavity, will usually be absorbed: if the hemorrhage occurs between the layers of the broad ligament, it constitutes an extra- peritoneal pelvic hematocele. After the twelfth week the sac is liable to secondary rupture at any time up to term, and here again the situation of the placenta is of the same im])ortance in the prognosis as in the primary ru^iture. The foetus. The question as to the possibility of life for the foetus is influenced by the location of the pla'UMita. In the tubal variety, the most favorabh* attachment of the placenta is on the floor of the Fallopiat' tubii, ns there may be slight if any disturbance of the fiBtal circulation if the .%0 MEDICAL AND SURGICAL GYNJICOLOGY. rupture be in the superior wnll, and the child may thus ^o on to full term. In ectopic gestation, even should the child be delivered alive, it is often deformed, puny, and rarely survives more than a day or two. Should the mother survive rupture, and the embryo die, it may be completely absorbed as it lies in the abdominal cavity, up to the second month; after that it either undergoes mnniniiji- cation, calcijicdtioii, or is converted into adipocere, or it decompoiics. Mummification is similar to that change which bodies undergo in a dry atmosphere. The tluid constituents are absorbed, and the soft tissues become leathery, or parch- ment like. In other cases the fatty elements are converted into adipocere. Either the mummified or the adipocere foetus may become partially or wholly calcified, and is then known as a lithopedian. The foetal mass may remain for a long time in the abdominal cavity, but should pyogenic organisms gain access to the sac from a neighboring organ, the fcBtus will be converted into a putrid mass which may be discharged into the rectum, vagina, or bladder. Symptoms. All the symptoms of normal pregnancy may, though not always, be present. In some cases, in- stead of amenorrhoea there will be profuse metrorrhagia with expulsion of some bits of decidua. This symptom is not to be confounded with membranous dysmonorrluBa, already referred to when sjieaking of that disorder. Pain is variable, in some cases it is almost constant, and in otluM's abs(>nt. When present before rupture it may be sharp and lancinating, or a dull heavy aching. Changes occmr in the external genitals similar to those in normal preg- nancy, together with softening of the cervix. On exam- ination, the Fallopian tube of one side will be found enlarged, and, if far advanced, will be forced from its normal position. ShouUl pregnancy have advanccnl to the tliird or fourth month, a tumor with a well defintul area of dullness on the anterior abdominal wall may be made out ECTOPIC (IKSTATION. 861 by percussion. By va^innl oxniniiuitioii tlu^ tumor will bo found Intornl, unci jit one side of tlie uterus with u sulcus between them. Rupture. The symptoms of rupture are very pro- nounced. A patient in prmMously good health, complain- ing^ only of some mild form of disturbance, and possibly with some of the earlier symptoms of prej:;nuncy, is suddenly seized with severe lancinating, cutting, or agonizing abdominal pain. If the hemorrhage is extensive, she may fall almost as unconscious as if struck a blow. Soon tliere are the usual symptoms of severe intc^rnal hemorrhage, indicated by a rapid or almost imperceptible pulse, quickened jerking respiration, air hunger, vertigo, nausea and vomiting, and dimness of vision. These symptoms soon merge into those of profound slioc!k, the extremities becoming cold and clammy, tlu^ skin pal(% the conjunctiva; pearly, and the face drawn. Death may follow at once, or it may be delayed for a day, or even longer. In some cas<^s the hemorrhage ceases for some time, to begin some days later and then prove rapidly fatal. When rupture occurs into the broad ligar nt the initial attacik is similar, but the subseciuent symptoms are not so urgent, and the hemorrlmge will soon cease from its own pressure. Should tlu> embryo die there may be no further trouble, but often the fditus continu(^s to develop, and sooner or later a secondary rupture occurs. In those rare cases which go on to full term, labor like pains, closely resembling normal labor, come on, and may continue for hours, or even days, and then c 5ase. During this time escape of blood, and of portions of the decidua occur in a majority of cases. When the patient survives rupture the sharp labor like pains subside, the breasts diminish, the tumor decreases rapidly in size, and she may regain her health in time, ii62 MEDICAL AND SURGICAL QYNiECOLOGY. absorption, or one of tlio othor changes tlint rondor the fcEtnl body innocuous, taking place. Diagnosis. A careful review of the cliiucal history will often lead to a suspitaon of the condition. A multi- para, who, perhaps, has not borne any children for some years, and probably has had in the meantime an attack of salpingitis and pelvic peritonitis, develops the early symptoms of pregnancy. There will be more or less dull ovarian pain, which continues until it terminates in the paroxysms of ruptuns and which, if not fatal, is followed by marked auiemia. A bimanual examination, taken in conjunction with this clinical history, will point certainly to the nature of the pregnancy. A rctrovcrfcd j/rdvid uterus may give rise to mislead- ing symptoms, but a careful vaginal and rectal palpation will make out the eidarged fundus. Ovarian tumors and cnlarficmoit of tlic Falloju'an, tubes associated with intra-uterine pregnancy, may lead to error, but the fever which accompanies pyosalpinx in the majority of cases will mark the difference. If it be impossible to arrive at adefinito conclusion, it is justifiable to recommend exploratory coeliotomy. The ru])fure of a p}jOsali)in.r may be mistaken for a ruptured tube, but when such occurs, the clinical history is entirely different, the pulse is not so rapid, the temperature rises rapidly and steadily, the patient does not present such marked symp- toms of loss of blood, but shows early signs of sepsis. It can scarcely be expected to differentiate between the tubal, ovarian, and the secondary abdominal form, when anato- mists fail to agree concerning them when the abdomen is opened. Treatment. Before rupture. The electrical treat- ment, once so much advocated, has fallen into disrepute on account of the uncertainty of terminating fcetal life, and its dangers to the mother. Nevertheless, as stated before, when speaking of the practical application of EOTOI'IC GESTATION. .%3 electric curroritH, its use mny bo couHidorod justifiable when the pntic^it is far removed from skilled hands, or when the patient positively refuses to submit to cdBliotomy. Should this procedure be decided upon, the transmission of the faradic current is accomplished by passing one pole into the rectum or vagina as far as tlu^ site of the ovum, and placing the other on the abdominal wall over the ovary. The full force of a one-celled battery is turned on for a period varying from five to ten minutes. The treatment should be continued daily for one or two weeks. Injections of solutions into the sac, such as half a grain of morphia, for the purpose of destroying the foetus, have also been tried and advocated. Undoubtedly when a diagnosis has beeii made previous to rupture, the proper course to pursue is the removal of the atfected tube. Cases with a history suggestive of ectopic gestation, and a mass lateral to the uterus detecttHl by vaginal examination, should be operated upon without hesitation. A proportion of such cases may prove to be pyosalpinx or hydrosalpinx, but the error is not a serious one, as in either instance operation is indicated. A f finir of rupture. If the patient is seen at the time of, or imnunliately afttM* rupture, the obstetrician must exercise much judgment in arriving at a decision. Should examination make certain that hemorrhage has occurred into the broad ligament, the method of treatment should be an expectant one, the possibility being that the hemorrhage will soon cease, if it has not already done so. Should examination reveal free fluid in the cul-de-sac, and there are no signs of improvement in the patient's condi- tion, intra-peritoneal rupture has doubtless occurred. In such a case operation is indicated, provided there is sufficient vitality left for it to be undertaken with any degree of success. In any case attention should bo directed towards arresting the hemorrhage, overcoming the shock, and sustaining the patient. Injection.:} of 364 MEDICAL AND SUKOICAL OYNiECOLOOY. strychnino niul brnndy may bo pfiven hypodormationlly, and infuHJoii of normal Halt Holutioi injocti'd into the radial artery or pectoral region, if tiie necessary appliances are at hand, or if not, into the rectum in the form of an enema. Ojwrdfion. After opening the abdomen clots should be turned out as rapidly as possible, and the ovarian and uterine arteries caught either with forceps or the fingers. If while clearing the pelvis fresh blood wells up, the bleeding points must be exposed, and hjemostatic forceps applied. Having controlled active hemorrhage, the rest of the operation, if pregnancy has advanced as far only as the first or second months, may consist merely of salpingo-oophorectomy. If. however, gestation has further advanced, attempts at removal of the placenta are ex- ceedingly hazardous, and the hemorrhage following its dislodgement may defy oontrol. No means further than those necessary to save life at the time of the operation should bo undertaken, and consequently the best course to pursue in such cases is to check the hemorrhage, cut the cord close to its placental origin, and leave the placenta undisturbed, to be removed by absorption or by subsequent operation. Drainage should not be employed as it in- creases the danger of sepsis. After rupture. Should there be a history of previous rupture occurring at the first or second months after gestation, operation should not be performed unless the foetus has ccntinued to grow. If the life of the foetus has not been destroyed at the time of rupture, the operation should be performed as soon as the patient has recovered from the primary rupture. As the dangers of operation greatly increase as the pregnancy advances on account of the development of the placenta, the earliest date possible should be selected. If the ijregnancy is in the early weeks, the operation may be no more difficult than salpingo-oophorectomy for hydrosalpinx, and is somewhat similarly ijerformed. If pregnancy has further advanced. PELVIC H/EMATOCELE. 3()5 and ndlu'Hioiis Imvo fornuMl botwcnni tlw pfostntiou hao iiiid tin* ndjdoi^iit viHc-cirii. or if it in a broad li^ainoiit i^ostatioii with tUv placHMita firmly implanted on tlu^ polvic fioor, tho opi^ration bccomoH nxciHMlin^ly difficult. Tho adhosions should be disHeetod off' oarefully, bleeding pointH ligated, and the Hac enucleated in the ordinary way. Kvdcudtlon of the ija^tdtlon Xdc fln'oiKjIi flic ViKjiiKt. After carefully examining tlui mawH and deciding upon the most accessible point for evacuation, usually in tho fornix, a pair of blunt-pointed forceps are thrust into the sac, and with the blades opened are partially withdrawn whih^ the sac is being steadied from above. The embryonic debris is evacuated with the finger inserted through tho opening, after whicih the sac may be washed out with a weak solution of bichloride, and afterwards packed with gauze. CHAPTER XXXI. PELVIC HyEMATOCELE AND PELVIC H/EMATOMA. The mere effusion of blood (intra-pelvic hemorrhage) into the pelvic cavity should not be confounded with hajmatocele, the term pelvic luumatocele being reserved for encysted collections of blood. When tlm blood effused and so encapsulod lies within the i)eritoneal cavity, it is termed intra-pcritoneul Itwrnatocclc, or simply pelvic, h(t'm<itocelc. When tho blood is spread out below the serous membrane, within the broad ligaments, it is called cxtrd-pcritoncdl luenuitoei'le or simply [wlcie hcrinatonid.. PELVIC HEMATOCELE. Etiology. The effusion of blood into the pelvic cavity may arise from tho tubes at tho regular menstrual period, the hemorrhage taking place from its distal end, and generally presupposes the existence of salpingitis. In such a case the amount effused may bo comparatively IMAGE EVALUATION TEST TARGET (MT-3) // f/. 1.0 I.I 1.25 1^ iilM U ■ 40 M Z2 2.0 R III! 1.6 Vi <^ /J / ^<^J c^l ^"^ "* / / Photographic Sciences Corporation 33 WEST MAIN STREET WEBSTER, NY. 14580 (716) 872-4503 36() MEDICAL AND SURGICAL OYNiECOLOGY. small, and may undergo absorption, or may become eTioapsuled from inflammatory adhesions. Subsequent tubal hemorrhages may increase the size until the hiematocelo may attain considerable proportions. The most common origin is recognized by all to be the early rupture of an extra-uterine pregnancy, and by some it is stated to be the only one. Other causes are assigned, such as rupture of varicosities of the utero-ovarian plexus, disorders of ovulation, abortions in connection with peritoneal adhesions, hematosalpinx or ovarian hwrnatoma, atresia of the cervix or vagina, and the rapid evacuation of the uterus for hjematometra. The tumor is usually situated in Douglas' cul-de-sac. At the outset the blood is liquid and for.ns a sort of lake, but the cyst, however, is rapidly formed, a..d is then entirely separated from the mass of intestines. In this way it is often difficult to distinguish the arch formed by the new membranes from an uplifted peritoneum. The uterus ia pushed towards the sympliysis .^nd the sac is adherent in front to its posterior wall, and to the agglutinated intestines which lie upon it. The sac contains a mass of coagulated, or syrupy stMni- liquid blood, according to the length of time the lesion has existed. Even in cases where there is reason to suspect tubal pregnancy as the cause, it is not usual to find any piece of the fcBtus, as it usually disintegrates and is absorbed. Symptoms. The appearance of hematocele is usually associated with symptoms characteristic of its production, such as those connected v/ith the uterine appendages, or ectopic gestation. It is seldom that the effusion of blood Kic. io6. — Retro-uterine haimatocele. U. Uterus. R. Rectum. A. Blood- clot. PELVIC H HEMATOCELE. 367 is noc ushered in by some decided disturbance. In the most severe cases, there mny bo those which have been mentioned as cliaracterizing ruptured tubal pregnancy. In less severe cases there may only be local pain, and a sensation of weakness, accompanied by an increase in the size of the abdomen; or the oozing of blood may be so insidious that the syra^)toms may be imperceptible. On making . iginal examination, a iluctuating tumor will be felt in i-ouglas' cul-de-sac which pushes the uterus upward so that the cervix is reached with difficulty, and when felt is found flattened against the pubes. By bimanual examination, the uterus can be outlined and seems to be incased in the mass which fills, or more than fills the pelvis. The course of the disease is essentially chronic, but successive attacks at times occur. In the most favorable cases, the patient is unable to walk for many months, and is exposed to repeated attacks of peritonitis, during which the tumor is subjected to change of size, and finally dim- inishes by degrees. Instead of this the tumor may remain for an indefinite period, with but little change in the syrupy chocolate colored contents. Suppurative inflam- mation may set in, and the mass may be converted into an abscess cavity, which increases its size and softness. Per- foration into the abdominal cavity is rare, but perforation may take place into the rectum, by which the whole mass may become evacuated and complete recovery follow. Diagnosis. The sudden appearance of a retro-uterine tumor coinciding with the phenomena of internal hemor- rhage is almost pathognomonic. It might be mistaken for a ruptured pyosalpinx or a retrovertod gravid uterus, I'Ut the diagnosis of these conditions has already been referred to in the chapter on ectopic gestation. Ovarian cysts and uterine fibromata have nothing in common with hematocele, their manner of appearance and course are entirely different. 368 MEDICAL AND SURGICAL GYNJICOLOGY. Treatment. Active interference is justified only by tl\e appearance of accidents which may endanger the life of the patient. If seen at once, absolute rest in bed is demanded, and ice may be applied over the lower abdominal region. Antisepsis of the vagina is to be attended to, to avoid all danger of infection through that channel. It is best to leave the disease to itself, so long as it follovrs a regular and progressive course towards absorption. Should such not occur within a moderate limit, or the ])atient'8 life is threatened by compression or inflammatory phenomena, rapid evacuation of the cyst becomes obligatory. Incision is preferable to puncture, and the site of the incision is to be determined by the protrusion of the tumor. If it projects plainly into the posterior cul-de-sac, it should be opened through the vagina. By the use of retractors the field of operation is enlarged as much as possible, and an incision is made following the axis of the tumor, care being taken not to injure the ureter by going too far forward in the lateral forviix. The finger in the rectum will serve as a guide in avoiding the intestine. After reaching the %iterior of the cyst, the opening may be enlarged and the contents carefully evacuated with the fingers, or by antiseptic injections. After clearing out the cavity, it may bt> loosely filled with strips of iodoform gauze, which will prevent further hemorrhage and complete the process of disinfection. The strips may be allowed to remain for forty eight hours. When removed the irrigation mny be renewed, and drainage kept up by strips of gauze inserted into the opening in the cyst cavity, and by a few pieces inserted loosely into the vagina. Cildiotomy has given good results. The walls of the cyst, if possible, are to be fixed to the abdominal parietes by caieful suturing, and the margins protected with pads of iodoform gauze. The cyst wall is then incised, emptied of its contents, and packed with gauze. Such fixation of the walls is often impossible, in which case the intestines PELVIC HEMATOMA. 369 aro to bo cnrofully tucked away, and the gonoral abdominal cavity thoroughly walled off with several thiokiiessc^K of iodoform gauze. When this has been carefully and accurately done, an incision may be made into the sac, and the contents removed by means of sponges. The cyst cavity may be then packed with iodoform gauze, and the occlusion pads previously inserted allowed to remain in Situ until sufficient peritoneal adhesions have formed around them to permanently wall off the peritoneal cavity, and with it the intestines, from infection. By this means also capillary drainage is established, and the broken down material of the cyst cavity removed. In course of time the gauze is gradually withdrawn, preserving careful antisepsis, and a smaller quantity reinserted each time until the cavity is completely filled up by granulation. PELVIC HEMATOMA. The effusion of blood into the connective tissue of the pelvis has also been designated by the term thrombus of the brodd liijoment. Etiology. It may be produced by the influence of pregnancy, or by rupture of a utero-ovarian varicocele. The immediate attack is usually the result of overwork or sexual excesses during pregnancy or the menstrual period. Pdthology. The blood may form a circumscribed tumor between the folds of the broad ligament, which not being a closed cavity, but communicating with the pelvic cellular tissue, permits the escape of blood, if abundant, into the latter, and the effusion then is directed toward the vagina and rectum. The tumor is usually of medium size, varying from the size of the fist to that of a man's head. The locality is decidedly lateral, and the contents similar to that described v>^ben speaking of intra-peritoneal hajmatocele. Symptoms. It usually occurs in women who are apparently in a healthy condition. Sharp pain in the 370 MEDIO\L AND SURGICAL GYNiECOLOGY. nbdomon marks the onset, accompanied by a tendency to syncope. Symptoms of decided ansemia, and troubit r. due to compression of the bladder are manifested, witli swel- ling and tenderness of the abdomen. By bimanual exam- ination, a tumor soft and pasty in consistence is felt in the broad ligament, and not in Douglas' cul-de-sac. The uterus is situated upon its internal surface and more or less pushed aside, but it can be distinctly outlined on every side. As for the other symptoms, they are the same as those given for intra-peritoneal hematocele. Treatment. Expectant treatment is the rule. If the gravity of the symptoms calls for interference, vaginal in- cision may be dangerous owing to the possibility of wounding the uterine artery or the ureter. In such cases, coeliotomy may be performed, with evacuation and drainage as described for intra-peritoneal lu^matocele. It may be evacuated by a combined operation of coeliotomy and drainage through the vagina. After open- ing the abdoiainal cavity and protecting it after the mannev already described, the sac is carefully incised and the contexts removed. Gruided by the lingers of one hand in the vagina, an opening is made through into that canal. The sac is then loosely packed with strips of iodo- form gauze, the ends being brought out through the /' vaginal opening, and drainage established by that route. The edges in the upper opening in the sac are then in- verted and drawn together by a continuous catgut suture and protected by gauze. The management of the gauze within the peritoneal cavity will be the same as already described. GENITAL TUBERCULOSIS. 371 CHAPTER XXXII. GENITAL TUBERCULOSIS. Tuberculosis of the female genitals, although long known, has only recently attracted special attention. It was previously known only as a concomitant of advanced phthisis, and it was not until coeliotomy demonstrated its frequent occurrence, either alone or in combination with tubercular peritonitis, that its clinical importance began to be appreciated. It may involve any or all of tlie various parts of the genital tract, though some portions are more frequently affected than others, the order of frequency being the tubes, uterus, ovaries, vagina, cervix, and vulva. Etiology. Tuberculosis of the genital tract may bo either primarif or scconddry. Primary inoculation may occur when the patient has been much in the company of one suffering from tuberculosis. The clothes, a sound, or the fingers of a physician may carry the germ. Cohabita- tion with a person who has either genital or pulmonary tuberculosis is a well authenticated cause in many instances. The puerperal state has a large share in primary infection, but whether infection can come through the semen, the saliva, or the blood of a scratch, is a disputed point. Secondary genital tuberculosis is that which is devel- oped ill the coarse of tubercular degeneration of other organs, especially the lungs. In the great majority of cases, genital tuberculosis is secondary and metastatic, the infection taking place by way of the peritoneal cavity and the lymph channels, from the abdominal viscera, or through the general circulation from distant organs, or by auto-inoculation from the secretions. Vulva. Vulvar tuberculosis is the least common, and is often unassociated with tuberculosis of other portions of the genital tract, being due either to blood infection or 372 MEDICAL AND SURGICAL GYNiECOLOGY. to direct infoction. Tlui tubtTouIous ulciern may attain a couHidorablo sizo and are usually Hhallow. Tluur marj^iiis aro irregular, sharply out. slightly raised above tlie general surface, and of a more or less granular appearances Vagina. Vaginal tuberculosis is much mor(^ frequent, and while it may bo primary, it is usually secondary to tubrtrculosis affecting the higher portions of the genital traci It occurs in the form of miliary tubercles, never larger than millet seeds, and which in time undergo caseation and break down, producing tuberculous ulcera- tion. The ulcers thus formed are irregular in outline, their margins sharply cut and perpendicular, the base shallow, studded by granulations of varying size and color, and covered by a layer of caseous material. These ulcers by extension may jierforate the walls upon which they are situated and lead to the formation of fistul{T3. It is gen- erally limited to the posterior wall of the vagina, and does not ordinarily extend below the upper third, circumstances which are explained by the fact that infection generally takes place by secretions from the tuberculous uterus or tubes. Uterus. Tuberculosis of the uterus is not a rare affec- tion. It is generally associated with tuberculosis of the tubes from which it has usually originated, and is fre- quently secontlary to phthisis, or occurs as a part of a general infection. It is nearly always limited to the corpus uteri. When tuberculosis of the cervix occurs, it is usually without any involvement of the body, and appears eitluT in the form of miliary tubercles, or of tuber- culous uka>ration, or as a combination of both forms. It is at first limited to the endometrium, but later the muscular coat becomes involved. The formation of the miliary tubercles occurs just beneath the epithelium of the endometrium, and may or may not be combined with in- flammatory changes. The appearance of the tubercles, and of ^he ulcerations resulting from them, does not differ (lENlTAL TUBliUCULOSIS. 373 t'HHriitinlly from that obsorvcd in tuln'rculoHis of other inu(H)iis miMnbrfines. In (rhroiiic ditt'uHo tulwrculosiH, tho iiiti'rior of tho body of tlie uterus in filled with casoouK matorial which forms a lay(>r ovct its inner surface. On H(Ta[)inK it off tiie sub- jacent tissue is seen ja^^ed and irregular, and stuchled with tubenies in all stag<?s of development, from the typical grayish semi-transparent nodule, to the irregularly shaped ulcer. As the disease progreasfiS, tubercles are gradually formed in the muscular coat, which accordingly undergoes hypertrophy, and leads to a consitlerable on- r. I. »•,(>. Fig. 107. — Primary tuberculosis of the tubes ami ov.iries, posterior view. ( Kotscfiau.) r.o. KiRbt ov.iry, enclosiiiK laseous m.-isses ev.ncuated by the tearinu apart of iulliesions. r.t. KiKhl lube, ililateil and .i<lh'ireiu to iliuui, havini; fornieil part of llie w.ill of a tuberculous abscess. Mie left ovary, tube, Lo. an<l l.t., and endonietriutn, c, .ire also tuberculous. largement of the uterus. By obliteration or clogging up of the cervical canal, it may lead to the formation of a pyomc^tra. Tubes. The Fallopian tubes are far more frequently affected by tuberculosis than any other portion of the genital tract, and in the great majority of cases either the uterus, or the ovaries, or both, are likewise affected. In most cases it is secondary to tuberculosis elsewhere, although in a considerable number of cases they are the seat of the primary form. ii74 MEDICAL AND SUKOICAL GYNiECOLOOY. Tubonnilosis of the tubes may oocur in two forniH. Miliari/ fiihcrriilosis, in which 11 o tubes present the fjfenernl charncteristics of miliary tuberculosis of other mucous membranes, and chronic diffuse tuhcrcnh^iis, which corresptmds to the like named process in the uterus, and is the form familiar to all under the name cuscons 2)us ti(l)rs. In advanced cases the tube is greatly enlarged, and if the peritoneum is involved, its external surface is studded with tubercles in various stages of development. It is densely adherent to the surrounding structures, and in some cases i^resenta an almost stony hardness. In most instances the fimbriated extremity is occluded, but when patulous caseous material will be found protruding from it. On section the lumen is found more or le.ss dilated and filled with typical yellowish caseous material, which varies greatly in consistency, sometimes being fluid, some- times it forms a soft mass, and occasionally is dry and solid or even calcified. The normal appearance of the mucosa has disappeared, and i>resents a ragged, ulcerated sui face over which are strewn tubercles in all stages of development. A third form of tuberculosis of the tube has been described, chronic jihroid tuhcrcnlosis. It differs from the others in the excessive formation of fibrous tissue in and between the tubercles. Ovary. Tuberculosis of the ovary is comparatively rare, and when seen is usually found in combination with other forms. The process may be limited to the surface of the ovary, or it may invade the entire organ. Macros- copically it appears in the form of miliary tubercles, caseous masses, or tubercular abscesses. Symptoms. No period of life is exempt from genital tuberculosis, but the period in which its occurrence is most frequent is that of the greatest sexual activity. The early symptoms are often not very clear, or so masked by GENITAL TUBERCULOSIS. ^75 thoHd of tlip primary affection that, the involvoincMit of tlio ^onitals is not Huspocted. When it occurH in tlui vulvu and vagina, it gives rise to symptoms oommon to all ulcerative processes, and in these instances simple inspec- tion is fre(piently all that will be reipiired, but a positive diagnosis can be made only by the microscope. Tuberculous ulceration of tli<i cervix may show itst^lf by profuse hemorrhage, and in that way may be mistaken for carcinoma. In cases in which the uterus is affected there is usually a very profuse leucorrluBa, which in some instances consists of a mixture of the caseous material and the ordinary secretions. The uterus will be found enlarged, and there will bo associated with it menstrual disturbances. The symptoms produced in tuberculous disease of the ovaries and tubes <,re in most instances overlooked in the generul condition, and even no symptoms at all may be present. When the process is limited to the tubes and ovaries, the symptoms will vary from those of a simple salpingitis to those of the most severe form of pelvic abscess, and in spite of careful examination nothing will be found to indicate the tuberculous nature of the affec- tion. Amenorrhoea is not necessarily an accompaniment, but if it occurs it is usually due to the coexisting phthisis. Diagnosis. From the clinical history afforded, it be- comes evident that prior to the discovery of the tubercle bacillus a positive diagnosis of genital tuberculosis could not be made. Tuberculosis of the vulva and vagina may be con- founded with (jr(tni(l(ir inujiniUs. When the frequency of the latter is compared with the rarity of the former, it is in itself almost sufficient for a diagnosis; but when one considers that when tuberculosis of the vagina occurs it is in phthisical women, and that granular vaginitis is frequently associated with pregnancy or gonorrluea, a mistake should not occur. Tuberculosis should also be .37(5 MUDKiAL AND SUIUlKiAL (lYNiECOUKJY. (liii^iioHod from Uw pdpiihir and ulcrntfin' si/plu'lidrs, which may bt< doiio by thti hiHtorv by th(i rutins abHuace of pain, and by thci total disappi^aianco of tho lattor uiidiir antiKyi)hiliti-.; trcvitiiKMit. JlcrfX'fic cniitlions about thc^ vulva oocnir as Hinall cysts tilled with cKwir fluid, aiid usually appcmr about tho monstrual period, and disappear soon after. Ihinl and .so/7 cliancrcs may be diagnosed by tho history, by tlu^ appearance of the patient, and by their well known characteristics. Tuberculous ulceration of the cervix nay be diat^nosed from ('(irrinonid by the aid of the microscope. In tuber- culosis of the uterus, and in all cases where there is the slightest suspicion of genital tuberculosis, the vaginal and uterine secretions should be inspected with the greatest care for tubercle bacilli. Tho diagnosis of tuberculous disease of the tubes and ovaries is more difficult than that of tuberculous disease of the uterus, for the reason that their secretion is not so readily obtained for examination, and it is doubtful if, when the disease is limited to these organs, a i^sitive diagnosis can bo made. Diagnosis. Primary tuborciilosis of the genitals is always to be regarded as a serious affection, as it always presents the possibility, as do other foci of tuberculosis, of a general infection, with its uniformly fatal termination. Tuberculosis of the tubes and ovaries tends to the produc- tion of tubercular peritonitis, or it may go on to the for- mation of an abscess in them. The results of operative treatment have been quite satisfactory. If the tuberculosis is limited to the tubes and ovaries, the prognosis after removal will hardly be more grave than if they wore re- moved for tho usual inflammatory affections. Treatment. Remembering the sources of primary in- fection, the necessity for prophylaxis becomes apparent. Possible infection by physician or attendant should be carefully guarded against. Persons afflicted with genital TUBERCULOSIS OF THE PElilTONEUM. 377 tuborculofliH, wliotlior mnlo or ft^innlo, should \hi improHHod with thl^ dnngorH of infection by coitus. The trtiiitiiKitit will vary nccordiiig ns different portions of the genital tract are affected, and whether the affection is primary or secondary. Ulcers of the vagina and vulva may be made to dis- appear by the application to tliem of tincture of iodine, iodoform, or la(;tic acid. If a tuberculous ulcer of the cervix is recognised, and fails to respond to conservative treatment, it should at once be amputated. If the process is limited to the uterus, it should be curetted and iodoform suppositories inserted. If there is the slightest recurrence of the infection, the uterus should be removed by vaginal hysterectomy, and in such cases it is best to remove tlio tubt>s and ovaries as well. The question as to the removal of the tubes and ovaries when they are the sent of tuberculosis, is a difficult one. As primary tuberculosis is rarely diagnosed, the propriety of their removal is seldom faced, but when discovered in cases of coeliotomy undertaken for other causes, there should be no hesitation as to the propriety of their removal. In advanced or decided cases of pulmonary phthisis, there should be no thought of operating. In cases associated with tuberculous peritonitis, there need be no hesitation to perform ca3liotomy and remove the tubes and ovaries, and uterus as well, unless the general condition of the patient is altogether unfavorable. CHAPTER XXXIII. TUBERCULOSIS OF THE PERITONEUM. In connection with miliary and chronic pulmonary tuberculosis, it is not uncommon to find the peritoneum studded with small gray granulations, and they ai'e constantly present too on the serous surfaces of tuber- 378 MEDICAL AND SURGICAL GYNiECOLOGY. culous ulcers of the intestines. Apart from these con- ditions the membrane is often the seat of extensive tuberculous disease, which occurs in the following forms: — Acute miliarij tuberculosis, with sero-fibrinous or bloody exudation. Chronic tuberculosis, cliaracterized by larger growths, which tend to caseate and ulcerate, leading to perforation. The exudate is jjurulent or sero-purulent, and is often sacculated. Clironic fibroid tuberculosis, which may be subacu'e from the onset, or which may represent the final stage of the acute form. The tubercles are hard and pigmented, there is little or no exudation, and the serous surfaces are matted together Vy adhesion. Tubercular peritonitis occurs at all ages, and is common in children associated with intestinal and mesen- teric disease. The incidence is most frequent between the ages of twenty and forty. Symptoms. The process may be latent and not cause a single symptom, the condition being accidentally met with during ccBliotomy for some other lesion. Sometimes the onset is so sudden and violent that a diagnosis of enteritis or hernia is made. Many cases set in acutely with fever, abdominal tenderness, and the symptoms of ordinary acute peritonitis. Cases with slow onset, abdominal tenderness, tympanites, and low continuous fever, resemble typhoid fever very closely. Ascites is frequent, but the eft'usion is rarely large, and is sometimes hemorrhagic. Tympanites is generally present, particularly in the more acute cases. Fever is also a marked symptom in acute cases, and the temperature may reach 104° F. In many cases it is slight, and in the more chronic cases subnormal temperatures are common. Associated with this, there is usually abdominal pain, imperfect digestion, loss of flesh, emaciation, sometimes diarrhoea, and occasion.olly pigmen- tation of the skin, resembling at times that of Addison's TUBERCULOSIS OF THE PERITONEUM. 379 disease. A striking peculiarity of tuberculous peritonitis is the frequency with which the condition simulates, or is associated with tumor, and is to be remembered when making a diagnosis of abdominal and pelvic tumors. Orncntdl tumors may form from the puckering and rolling up of this membrane until it forms an elongated firm mass, attached to the tranverse colon and lying across the upper part of the abdomen. Sdcculdtrd cxmUi.fion may occur, in which the effusion is limited and confined by adhesions between the coils of intestines, the parietal peritoneum, the mesentery, and the abdominal or pelvic organs. This encysted exudate is most common in the middle zone, and has frequently been mistaken for an ovarian tumor. It mfiy occupy the entire anterior portion of the peritoneum, or there may be a more limited saccular exudate on one side or the other. It may be completely within the pelvis proper, associated with tuberculous disease of the Fallopian tubes. In rarer cases the tumor may be due co the great retraction or thickening of the intestinal coils. Not only the small intestine, but the entire bowel, from the duodenum to the rectum, has been found forming such a hard nodular tumor. Mesenteric glcmds occasionally form very large tumor like masses, but they are more commonly found in children than in adults. Diagnosis. The prodromata, the gradual onset, the progressive development, suggest the tuberculous nature of the disease. The presence of extensive induration about the Fallopian tubes, not traceable to labor, abortion or gonorrhoea, and of tuberculous disease elsewhere in the system, aid materially in differentiating it from peritonitis due to ordinary salpingitis or appendicitis. Mali</nant peritonitis is seldom encapsuled, and is more often connected with a tumor or characteristic enlargement of an organ, has less extensive acute attacks, and runs a more rapid course. When tuberculous peri- 380 MEDICAL AND SURGICAL GYNECOLOGY. tonitis progresses more rapidly, the charncteiistic symp- toms of it will prevent it being confounded with malignant disease. Encysted tuberculous peritonitis may, as has been said, be mistaken for an ovarian in mar. In addition to the local signs of ovarian tumor already mentioned, the presence of salpingitis, the induration of the sacro-uterine folds as felt by the finger introduced into the rectum, the slow development and other signs and symptoms of tuber- culosis, will serve to distinguish it. An ovarian tumor with pelvic adhesions presents severe increasing pelvic symptoms, with proportionately less general depression, loss of health and emaciation than tuberculosis. Treatment. The treatment in general consists in that which belongs to tuberculosis elsewhere. Attacks of peritonitic pain should also be treated on the general principles laid down for peritonitis occurring under other circumstances. Bismuth and salol, the digestive ferments, and a carefully regulated diet may be required for gastro- intestinal irritability and impaired digestion. Constipa- tion or diarrhoea should be combated by appropriate treatment. Counter-irritation over the abdomen by tinc- ture of iodine, and later by gentle pelvic massage, may be employed. Encysted peritonitis shouhl be relieved by lappi/ig, or by a short abdominal incision and the in- Kufiiation into the sac of a small quantity of iodoform. Drainage is seldom necessary, unless adhesions have been separated that leave oozing surfaces. PART FOUR. DISEASES OF THE FEMALE BREAST. CHAPTER XXXIV ANATOMY. THE NIPPLES. NEUROSES. MASTITIS. MAMMARY ABSCESS. CYSTS. For a proper consideration of the various affections of the mammary gland, it is essential that there should be a knowledge of its anatomical position, its structure, and its physiological functions. Into these it is impossible to go here, but a few points regarding its blood vessels and lymphatic channels will not be out of place. The breast receives nearly its entire arterial supply from the thoracic branches of the axillary, namely: — The acromio-thoracic, the long thoracic, and the external mammary arteries, all entering the gland from *^^he upper and outer aspect. Branches are sent to the sternal side of the gland by the perforating and intercostal branches of the internal mammary artery. The venous blood returns througli the veins accompanying the arterial vessels. The lymphatics of the breast consist of two sets, an axillary and a mediastinal. These are further subdivided into superficial and deep sets. The main lymphatic channels pass either superficially, or deeply, from the upper and outer portion of the gland, the former over, the latter in the fascia which covers the pectoralis major muscle. The majority of these lymphatics bend around the pectoral muscle and ontt^r the glands there; others pass directly to the glands about the axillary artery. Still others, belonging to the superficial set, pass upward and outward, joining first with the lymphatics of the arm before entering the glands about the axillary vessels. The 382 MEDICAL AND SURGICAL GYNiECOLOGy. mediastinal set of lymphatics, consisting of a superficial and deep set, drain the sternal side oi: the gland, particu- larly the upper and inner quadrant. T!iey pass into the glands of the anterior mediastinum by perforating the intercostal spaces, those on the right side joining usuully with the lymphatics from the convex surface of the liver. A knowledge of the lymphatic distribution is important, particularly in carcinoma, as it explains the common infection of the axilla, and the rarer infection of the mediastinum and liver which may occur in this disease. Malformations or deformities of the breast are very rare and of no practical importance. Diseases of the nipple. Apart from inflammatory disturbances, the nipple is rarely affected by disease. Inflammation may be excited by any irritation, but it is seldom found except during lactation, either early in its course, or when lactation is unduly prolonged. The alternate wetting and drying associated with nursing the child, is the exciting factor. In the mi.der cases the nipple and surrounding areola are ; fected only. In severe and neglected cases the process -ay involve the neighboring skin and underlying fascia, or even the gland itself. This extension is due to the Assuring which opens up the lymph tracts to the entrance of pyogenic micro- cocci. These micrococci, which are commonly present in the skin and mouth secretions, enter and excite lymphan- gitis, and by spreading deeply may set up mastitis, either of which may terminate in mammary abscess. In the milder cases the nipple and areola become red and swollen, then fissured, leaving small ulcers, constituting what is commonly termed cracked nipples. Pain is always present, usually smarting in character, and inten- sified during the nursing of the infant. In severe cases the ulceration may extend deeply, leading to considerable destruction of the nipple substance. .. DISEASES OF THE BREAST— NEUROSES. i^83 Tr'catment. In the milder cases thorough cleanliness is all that is usually required. Washing the breasts with warm boracic acid lotions, and thorough drying after nursing, v/ill accomplish this. When fissures appear, a breast shield should be worn when the child is nursing, and in the intervals an astringent lotion, such as the glycerolo of tannic acid, used. In severe cases the use of the breast will have to be abandoned, the ulcers touched with a caustic, such as the solid stick of silver nitrate, oud the breast compressed with a firm bandage after the appli- cation of a belladonna ointment or lotion, or bettor still, perhaps, the oleato of atropine in two-per-cent strength. Neuroses of the breast are not unfrequently found in young unmarried women. As a rule the condition is most marked at, or about the menstrual periods. This affection is qi 'te a common manifestation in hysterical women. The features usually noted are a peculiar sensitiveness in the gland, at times amounting to pain, neuralgic in character, and usur^ly localized, but may shoot to the arm or shoulder. On examination no departure from the normal can be detectv3d. It is important to examine the breasts carefully for tumor nodiles and to exclude these as causal agents. The treatment of these neurotic conditions must be directed to the general health of the patient, no attention being paid to the breasts; in fact attention should be directed entirely away from them, as local treatment usually intensifies the trouble. Inflammation of the breast. (Mammitis, mastitis, mammary abscess.) Inflammatory conditions of the breast may be either acute or chronic, but the vast majority of such must be placed in the former category. Acute mastitis may follow traumatism, but most commonly it is found during the first weeks of lactation, or late in its course, being due to the extension of infective material from cracked nipples. It may also be found in 384 MEDICAL AND SURGICAL GYNJICOLOOY. infaris shortly after birth, duo to attempts of the nurse or mother to break the "nipple strings;" ov at puberty, owing usually to some trauma or irritation of the then sensitive breasts. All cases of acute mastiffs, not directly traumatic, are due to the entry of infective bacteria, par- ticularly the pyogenic micrococci, of which staphylococci, pyogenes aureus and albus, play the chief part. Cold, inefficient emptying of the breasts, irritation from the clothing or other slight trauma, and prolonged lactation are factors predisposing to infection. Infection, though com- monly of local origin through the milk ducts or lymph channels, may at times take place by way of the blood current. The symptoms are at first a sense of fulness and discomfort, followed by swelling of the breasts and ten- derness, often localized at first to a single lobule or group of lobules. Pain is present, sharp and lancinating, and often shooting to the axilla. The skin next becomes tense, red, and indurated. Constitutional disturbances are manifested by slight chill with subsequent fever. The inflammation may terminate in resolution, or it may pass on to suppuration and the formation of an abscess. Mammary abscess. When the inflammation termi- nates in pus formation, the parts, usually localized to a group of lobules, become tense, boggy, and fluctuation appears. In true mastitis pus forms in the gland, but pus may form either over or under the gland. Superficial abscess formation may mean no involvement of the gland tissue, but frequently it is but a forerunner, or rather a concomitant of abscess formation in the gland itself, Pus formation beneath the gland is commonly due to the direct passage of infective pyogenic bacteria to the lymph tracts in that situation, the gland itself being only occa- sionally involved. In such cases the inflammatory process is behind the gland, and when pus forms the gland is pushed forward and floats, as it were, upon it. Pointing DISEASES OF THE BREAST- -MASTITIS. 385 of the abscess usually takes place at the lower margin of the breast. Trcdttnciit. The treatment of mastitis at p'jrioda other than lactation, consists in keeping the gland at perfect rest. This is best secured by bandaging with firm com- pression the affected breast, and at the same time fixing the arm to the chest. The bowels should be opened by a sharp saline purgative, and kept acting freely. Tonics should also be given. Locally, soothing astringent lotions, as lead and opium wash, should be applied to the breast. If the inflammation tends to pass on to pus formation, these lotions should be replaced by hot fomentations, or by aseptic poultices, such as linseed meal boiled in carbolic water (1 to 80) . When pus forms it must be freely opened. Mastitis during lactation always shows a great tendency to proceed to abscess formation. During lactation, if mastitis develops, the child should be withdrawn from the breast, and distension relieved either by gentle stroking, or by the proper use of the breast pump. The breasts must also be placed at perfect rest by firm bandaging, and other points attended to according to the manner already described. If pus forms it must be evacuated at once. In opening an abscess in the breast the incision should always be made in a line radiating from the nipple, thus avoiding the milk ducts. The opening should be freely made, the abscess cavity irrigated and packed with a little iodoform gauze, and the skin incision partly approximated. When the abscess is behind the gland, the incision should be made where the abscess tends to point, that is at the lower border of the gland. After evacuation of the pus the cavity should be thoroughly irrigated and drained as before. A rubber drainage tube may be sufficient for such cases, as the dependent position affords in itself good drainage. Chronic mastitis. (Interstitial mastitis.) Chronic in- duration of the breast is a proliferative inflammation of 386 MEUICAL AND SUUQIOAL GYN/ECOLOGY. some of its lobulos. It may be due to various onuses, nutl there are differont varieties. It may bo found arisinji^ Jato during lactation, or more commonly in married women after the menopause. In both these conditions it may be mistaken for carcinoma, and 't is well to remember that 8' me ^f such cases do terminaio in carcinomitous for- mation. Besides those commoner conditions, we may have a chronic mastitis set up by continued irritation of the clothing. Tuhercnlosis and syphilis at times attack the breast, usually taking the clinical form of chronic mastitis. Either of these conditions may lead to the formation of chronic or cold abscess of the breast. Abscess formation is at times found in connection with chronic mastitis occurring late in lactation. In chronic mastitis there is an extensive proliferation of the connective tissue cells, and to a slighter extent of the epithelium of the gland alveoli, with a slight leucocytic infiltration. The connective tissue cells develop into adult fibrous tissue, and by their contraction load to in- duration, and to occasional adhesion of the skin and retraction of the nipple. The gland acini are also pressed upon and gradually destroyed. In some parts small re- tention cysts may be formed by the obliteration of the ducts. The disease is first noticed as a circumscribed indura- tion in the breast, moving only with the breast tissue, and affecting but one or two lobules at first. The affected area is tender on pressure. Pain, if present, follows the distribution of the intercostal nerves. The indurated area is commonly wedge-shaped, with apex toward the nipple, and gradually increases in size. The induration has not the stony hardness of scirrhus, nor does it become adherent to underlying structures. The axillary glands are at times somewhat enlarged, but never indurated. The skin over the area of induration may become somewhat dimpled, and the nipple retracted, owing to the contraction of the DIUEASES OF THF BRii.\ST — CYSTS. 387 nowr rormod fibrous tissue, ^n n cnso wlicro tho din^nosis botwoen this affection and scirrhus is doubtful, thoro should bo no hesitation in making an exploratory incision, for in this, as in the case of scirrhus, early operation is the only hope for eradication of the disease. Trcdtment. Tonics and good food are indicated in most cases of chronic mastitis. Potassium iodide may also be administered, and is essential in syphilitic cases. Locally, various preparations may be made use of, such as a two-per-cent oloate of mercury or iodide of potassium ointment, or belladonna plaster. When used they should be applied with firm pressure, and the treatment continued for some weeks. If pus forms it must of course be im- mediately evacuated and the cavity irrigated and drained. In cases persisting for months, and in tubercular mastitis, amputation of the breast is called for, as long continued cases, if left alone, are apt to become malignant. Simple cysts. Cysts may occur in nearly all forms of tumor of the breast, the common cysts being found in connection with adenomata of the breasts, but the cysts to be now considered are those apart from such tumor forma- tion. Of the simple cysts there are two classes: — 1. Serous cysts, due to distension of lymph spaces in the connective tissue stroma. They contain a torous fluid and seldom reach a large size. 2. Retention cysts, of which there are several varieties. (a) The large duct cysts. (/>) Small duct cysts or gland- ular cj'sts. (c) Involution cysts. The duct cyst is due to blocking of one of the larger milk ducts, leading to distension of the duct. Occurring during lactation, such blocking leads to milk cysts or galatocele. The smaller duct cysts are usually multiple, and are due to dilatation of smaller ducts and gland alveoli, from blocking of the lobular ducts. These cysts contain a yellow, or a brownish yellow mucoid fluid. The third class, or involution cysts, are of very small size, and 388 MEDICAL AND SURGICAL QYN-ECOLOGY. occur in oldorly pooplo, or as a result of chronic inaHtitis. Thoy nro of no importnnco. Homorrhago may occur into any of those varieties, forming a nemorrhagic cyst. Serous cysts and duct cysts give rise to the same symptoms, and are found most often between the ages of thirty and forty years. They appear as rounded or ovoid swellings, situated usually in the centre of the gland, have an elastic feel, are freely movable, and do not lead to skin adhesion. Galatocele or milk retention cysts occur during lactation, and are filled with a milky fluid changed by absorption and inspissation. The treatment consists in laying open the cysts and removing the contents. In serous cysts the cavity may be allowed to granidate up from the bottom. In other forms it will usually be necessary to dissect out the cyst wall, or to remove the effected zone entire. In such cases the wound may be sutured and treated as an ordinary incision. CHAPTER XXXV. DISEASES OF THE FEMALE BREAST CONTINUED. NEOPLASMS. Tumors of the breast constitute the largest class of affections of this organ. Various classifications are given in the larger text books, but the following is here put forward as resting upor a fairly accurate pathological and clinical basis. Tumors of the breasts may be: — 1. Simple OT innocent ; 2. Mdlignant. I'his classification must be further subdivided as follows: — 1. Benign, innocent, or histioid tumors made up of: — a. Tissues resembl/ng the fully developed connective tisswes, as fibroma, lipoma, -o I chondroma, etc. />. Tissues resemblinj;^ the more specialized connective tissuen, as angioma, neuroma, etc. DISEASES OP THE BREAST - -NEOPLASMS. 389 Common Hiiuplo tumor. Usunl sarcomatous tumor. V. Tissues coriHistiug of opitholial olcmc^nts nirnnged fairly typically in alvooli, with distinct lumon, and a stroma of fully developed connective tissue, as adtuioma and its subvarieties, adeno-fibronm, cyst- ndonomn, and papillary cysts. 2. Mdlifjiuirit tumors made up of : — Ui. Tissues of the nature of class, e, in simple tumors, in which the stroma is not fully developed, but embryonic, that is con- sisting of young forms of connective tissue, adeno-sarcoma and its sub-class sero-cystic .sarcoma. The distinction between class, r, and this one is often more pathological than clinical. b. Tissues made up entirely of embryonic, that is to say, young forms of connective tissue. Sarcoma (pure). ('. Tissues made up of glandular epithelium arranged atypically in alveoli, by a con- nective tissue stroma, and without base- ment membrane. Carcinoma. Of all cases of tumor of the breasts, including cystic tumors, over eighty per cent are carcinomatous, and about three per cent sarcomatous, either pure sarcomata or adeno-sarcomata. Thus malignant tumors constitute about eighty five per cent of all breast tumors. ( )f the remainder, . adenomata or their subvarieties constitute nearly the entire percentage. The simple tumors, fibroma, lipoma, angioma, and adenoma are rare, with the exception of the last named, end as they do not differ from similar tumors situated in other regions, it will not be necessary to refer to them further here. Adenomata. These tumors are made up of epithelial cell elements, spheroidal or cubical in shape, arranged in olveoli with a distinct lumen and a limiting base- ment membrane, by a fibrous connective tissue stroma. 390 MEDICAL AND SUROICAL GYNiECOLoaY. Puro ndiMiomnta closoly rof«niblo tho true glniul Hhhuo itwlf, (liffiiring howovor in tho niraloHS nrnmgomoiit of ti nlvooli, niul thd nbsenco of tho propor ducts. In the pure form ndciiomatn nn^ rnns commonly wo find in Huch growtiiH a coiiHidiiniblo nmount of fibrous stroma, (jonsti- tuting Jihro-ddciKnud, tho couimon simple tumor of the bronst. Other modifications in structure of the adenoma are found constituting further subvarioties. Some of tho glandular alveoli may dilate, and their lumen become filled with a serous, mucous, or more rarely, a milk-like fluid, at times somewhat dark in color. These dilated alveoli may themselves etdargi^ greatly, or more commonly neighboring dilated alveoli run together forming smaller or larger cysts, and constituting tho cijstic (tdcnomata of the breast. Into these cystic spaces prolif^^rous ingrowths of the cystic wall.-}, consisting of tho frame work of connec- tive tissue covered with the epithelial lining of the cyst wall, may occur. These ingrowths constitute tho pvo- lifcroHs nuimmdrj) cysts, or piipilldvy cystonuifd of the breast, and are analogous to the papillary cysts of tho ovary. Cystic adenomata constitute about eighty five per cent of the various cystic formations in the breast. In some adenomatous formations the stroma, instead of btdng of a type of fully developed connective tissue, contains more or loss embryonic or young connective tissue. These are the adeno-sarcomdUi of the breast. At times the epithe- lial lining of the alveoli of the tumor takes on an atypical course, breaking through the basement membrane, forming atypical alveoli. This is a cdrcinomaious change and though it occurs but rarely, its possibility should always be borno in mind. Adenomd and jibro-ddenoma may bo considered to- gether. These tumors are found nearly always between the ago of puberty and thirty five years, being most com- mon between seventeen and twenty seven. They occur as a rule in otherwise healthy women. The tumor appears as DISEASES OP THE BREAST— NEOPLASMS. 391 jiHlowly growing iukIuIcs commonly in the uppc'r linlf of tlio ^land; it in frot^ly movablo, (unuimsrribod. and roundt^l, and at times lobulatwl. The noduU'H foci firm, and may vary in si/.o from a poa upwardH; commonly tl'.cy reach tlic sizo of a wjvlnut, but con.sidi^rably lHr^l^r growths may be found. The nkin \h rarely involv(>d, and if ho, only by direct presHure. The growth may become^ more rapid during pregnancy _ or lactation. Pain in the iflss^xvK v,v nodule i* seldon. '^om- '^^M^^f^f^J^Uv'^ ;"SF--*a8 Vui. io8. — Fibro-atlenonia of the breast. The glandular tissue is l).-\<lly developed, and is mingled with nnich filirous tissue. plained of, but tii«ro may be uneasinesH oi slight tendernesB in neurotic patients. Shooting pains through the breast are not an infrequent symp- tom, but the axillary glands are not involved. Cijstic (idenomd usually occurs at a somewhat later period than tibro-adenoma, being most common between thirty and thirty five years, though not wholly confined to that period. The tumor grows larger than the simple adenoma, which they resemble clinically, at times reaching one or two pounds. Their later appearance, larger size, their frequent irregularity of surface, and the demonstra- tion of points of fluctuation, are diagnostic features. Many of the cysts are so tense that fluctuation may be most difficult to make out. The papilldry cysts present the same general features as the cystic tumors. Often the cysts are so filled with ingrowths that clinically these tumors are solid, and they may even appear, on superficial examination when re- moved, to be solid fibro-adenomata. Cystic adenomata do not invade the breast tissue, but pressure may lend to atrophy. The skin may be involved 392 MEDICAL AND SURGICAl GYNiECOLOGY. by pressure of a largo tumor, but it is never infiltrated. The glands are not involved except there bo some accom- panying inflammation, when they may be slightly enlarged and tender. The treatment of all varieties of adenomatous tumors is excision. Whon they involve but a small portion of the gland structure, as in most cases of simple adenoma and Fig. 109. — Proliferous cyM adenoma— «, termination of an acinus; h and c, the tissus lie tween the .-icini taking on incrc.->sed Rrowth and pushing into and dilating the acini into cysts. (Billroth.) early cystic trouble, the growth cpn be excised without injuring the secxetive function of the breast. The skin incision in such cases should radiate from the nipple, avoiding the ducts, and should cut to the capsule, when the growth may bo either enucleated or dissected away with its capsule. Enucleation is advisable in simple cases, while if cystic change occurs, the latter procedure should be employed. When the tumor is large, or involves the gland tissue extensively, the breast must be amputated. DISEASES OF THE BREAST — NEOPLASMS. 393 Recurrence after complete removal does not take place. Further nodules may occasionally appear, but these will have developed from now foci. Sarcoma and adeno-sarcoma. About three per cent of the tumors of the breast are sarcomata, and the majority of them belong to the mixed variety, adeno-sarcoma, the remainder being derived from the connective tissue with- out change in the epithelial elements. Sarcomata begin most commonly between the ages of thirty and forty, and attack chiefly the central area of the gland. Ac first they appear as small, slightly lobulated, freely movable growths, and early it is impossible to differentiate them from adeno-fibromata. The growth, however, is much more rapid, advancing as much in weeks as the simple tumor does in months. The growth soon becomes large, less movable, and often somewhat adherent to the surrounding parts. It is also more elastic, softer, and of more unequni consistence than a simple tumor. In an adeno-sarcoma the glandular part may undergo the same changes as occur in simple tumors, and cysts roa;y thus be formed. Cystic sarcomata rapidly enlarge, and hemorrhage very frequently takes place into the cysts. As a rule, sarcomata of the breast are, until late in their course, distinctly encapsuled. Later they infiltrate the gland structure and involve the skin, which becomes first blueish, and its veins dilated. Later the skin becomes dusky red, and ulcerates, owing both to pressure and infiltration, After ulceration the tumor may protrude as a bleeding fungoid mass. The axillary glands are seldom involved, as dissemination occurs by way of the blood current. SeccJary growths are most common in the lungs, and when they occur, are always of the nature of pure sarcomata, even though the primary growth be an adeno-sarooma. Treatment. In the early stages the treatment does not differ from that of adeno-fibroma. Later amputation of the breast with free and wide extirpation of the surround- 31)4 MEDICAL AND SURGICAL GYNAECOLOGY. ing skin, is essential. With early excision recurren(!e is uncommon, but when the tumor is large, recurrence not infrequently may occur locally, or there may be a genciral dissemination of the growth. Local recurrences shouhl bo freely removed. The prognosis after free excision is fairly good, as about two thirds of the cases show no return. If left alone the tumor has always a fatal issue, due to ex- haustion from ulcerative discharges, or from continued hemorrhage, or to general dissemination, or to the cachexia which appears late in the disease. Carcinoma. Carcinomata, or cancers, comprise the vast majority of new growths in the breast, making up over eighty per cent of the tumor formations in this situation. As compared with neoplasms elsewhere, it also forms a large percentage, comprising seventeen per cent in the extensive series collected by Roger Williams. In tlie female, the breast and uterus aie the usual seats of carcinomatous formations. Carcinoma may attack the breast in all its varieties, but spheroidal-celled carcinoma is by far the most common, comprising from ninety seven to ninety nine per cent of such formations. All forms of spheroidal-celled carcinoma may be found — sci'rrhiis, enccphaloid, and culloiti— hut scirrlius is the most common form. S<)U(inioi(s-e('ll('(l car- cinoma or epithelioma may attack the skin surface subse- quent to a continued intractable eczema — the so termed Paget's disease. This is very rare, at least in this section. Colmmiar-celled carcinoma, originates from the ducts of the breast, comprising the villous or duct cancer. The spheroidal-celled carcinoma originates from the gland structure itself, and its varieties, scirrhus, encepha- loid, and colloid, are differences only in the amount and character of the epithelium as compared with the stroma. The larger the number of epithelial cells, compared with the stroma, the softer will be the growth, and the more malignant its character; the more embryonic in character DISEASES OF THE BREAST —NEOPLASMS. 395 the epithelial cells, the more rapidly will they tend to disHoniinate. Colloid cancer consists of a colloid degen- eration of the epithelium of scirrhus or encephaloid, a degeneration which lessens their malignancy very materially. In the causation of cancer of the breast there are the same factors which appear to predispose to it elsewhere. A family history of the disease is occasionally obtained. [ / I If,, no.— Section of a breast with scirrhus carcinoma. The growth infiltrates the fat, and has caused retraction of the nipple. Cases have been frequently recorded as fol]v)wing some traumatism. Long continued irritation, particularly when accompanied by proliferative (chronic) inflammation, as in chronic mastitis, is the most important predisposing causal factor. In the breast, as elsewhere, the actual causal agent of this distressing affection has not been found. Carcinoma is most frequently found towards the periphery of the gland, particularly in the upper and outer quadrant of the organ. No part is however free from attack. It is most common in women over forty, and more especially about the menopause. The vast majority of cases are found between thirty six and fifty two years, but cases are at times found in younger, and not in- frequently in more elderly women. The softer, or en- cephaloid variety, is more apt to occur in younger patients, 31M) MEDICAL AhD SURGICAL GYNiECOLOGY. than scirrhua. As sciirhus is by far tlie most common form found, it alono will be completely described. Scirrhus usually commences as a small rounded firm lump, which is at first movable, and commonly painless. Its early growth is slow, but later it becomes hard, nodular and less movable, or moving only with the entire breast. The outlines of the growth are ill defined, merging into surrounding mammary tissues and fat. Later the tumor approaches the skin, causing dimpling, and then puckering, while later still the skin becomes densely adherent, and finally may ulcerate. This involve- ment of the skin differs considerably from that of sarcoma or adenoma, for while in them the skin is first stretched and thinned by pressure before ad- hesion and ulceration oc- cur, in cancer there is puckering due to contraction of the newly formed fibrous stroma in the invaded fibrous septa stretching from the skin to the fascia covering the gland. The tumor sooner or later, by downward extension, becomes adherent to the pectoral muscle, and is then quite fixed. Later it may infiltrate the muscle fibre, and even pass through the intercostal spaces to the pleura. The nipple commonly becomes retracted, the retraction usually commencing somewhat sooner than the skin dimpling. This retraction is due to the contraction of tlie fibrous wulls of the milk ducts from invasion of their walls by the growth. The retraction is a true one, not like that occasionally seen in other tumor formations, where the nipple lies buried by the tumor mass. It is to be remembered that retraction of the nipple is not always Fig. III. — Scirrhus carcinoma of the breast. DISEASES OF THE BREAST — NEOPLASMS. 397 present, and further that it is often a late sign. At times a milky fluid can be expressed from the nipple, but this symptom may also be present in adenoma. Pain is absent in the early stages of growth, but later becomes manifest, at first slight and stinging, but later more severe sharp and cutting, and often shooting to the axilla. This pain is almost constantly complained of, but in rare cases entire absence of pain may be noted. Ths axillary glands are affected early in the disease by extension to them, through the lymphatics, of epithelial cells from the breast nodule. These glands become en- larged and tender, and though at first not palpable, later appear as shoty nodules. The glands along the lower border of the great pectoral muscle are first involved, and later those about the axillary vessels and brachial plexus. Owing to pressure on the axillary veins, oedema of the arm* often follows, while pressure on the nerv( .^ will cause severe neuralgic pain along their course. From the axillary glands there may be extension to thoee above the clavicle. In such cases the disease is usually considered to be beyond operative interference. At times extension occurs to the glands of the anterior mediastinum, and on the right side, to the liver. General dissemination may occur in the bones or viscera. In all cases of cancer of the breast, a careful examination should always be made of the axillary, supraclavicular, and anterior mediastinal glands, and of the lungs and liver. After adhesion of the tumor to the skin, little nodules may develop there; and it, in its turn, will become red, glazed and finally break down at some point. The skin all about the ulcerated and adherent portion becomes puck- ered and drawn towards it. In the ulcerated portions, a protruding fungus rarely *orms; more commonly there may be an ulcer with raised, everted, stony hard margins, and a rough irregular sloughing base, which bleeds readily. By the time the skin has ulcerated and the 398 MEDICAL AND SURGICAL GYNJICOLOGY. axillary glands have become enlarged, there will be develop- ment of the cancerous cachexia. Death may be dne to exhaustion from hemorrhage and local discharge, from general dissemination of the growth, or from involvement of a vital organ, or to some secondary infection or com- plication. Some exceptions should be made to these general state- ments regarding scirrhus. In some rare cases the growth may not begin as a localized nodule, but affects, as a diffused growth, almost the entire breast. In some cases known as atrophic or withering scirrhus found at times in quite old women, the growth shows great shrinking and density, and is of slow formation. This growth has not so much tendency tc invade the glands, but general dissem- ination may occur. Cases of scirrhus of the breast, when untreated, have an average course of thirty months; many cases do not run more than eighteen months, while others may be pro- longed for three or four years. Encephaloid carcinoma is very rare, and runs a much more rapid clinical course than scirrhus, a few weeks to about fifteen months being the limit. It occurs as a !*ule in younger patients, grows more rapidly, forming a large tumor in a few months. It soon involves the skin and glands, and rapidly disseminates in the internal organs or bones. Occasionally it attacks both breasts at the same time, and is then most rapidly fatal. Colloid carcinoma is a carcinoma in which the epithelial cells are undergoing colloid degeneration. Such cancers are of slow growth, do not involve the glands until late, and when removed have much less tendency to recur than the other varieties. It is in fact much less malignant. Duct carcinoma or columnar-celled carcinoma origi- nate s from the epithelium of the lactiferous ducts. The gro\» th is thus found in the centre of the g'ind. Growth, DISEASES OF THE BREAST NEOPLASMS. 3<.M) ns ft rule, is quite slow, the nipple is only occasionally re- tracted. The axillary glands are involved but rather late in its course. The growth, if left alone, reaches to and involves the skin, leading to ulceration and the protrusion of a fungous mass. When this form of carcinoma is freely removed the tendency toward recurrence is slight. Treatment and prognosis. In all cases at all amen- able to treatment, there is but one method that can be advised, and that is early and wide excision of the disease. This will include amputation of the breasv and t)ie re- moval of the axillary glands and pectoral fascia. This operation of excision of the breast, with clearing out of the axilla, is in itself not free from danger, but ranks as a major operation, with a death rate of from three to ten per cent. Needless to say the earlier and more radical the operation, the better will be the result, so that operation should always be undertaken as soon as a diagnosis has been made. The common, early diagnostic signs of scirrhus may be summarized as follows: — An ill defined, hard, and usually painful lump, occurring in the periphery of the gland, in a woman about the menopause, moving only with the breast tissue, causing somewhat later retraction of the nipple and dimpling of the skin, with early involvement of the axillary glands, will prove to be scirrhus. All of these features are of course not constantly found. Dennis says: "The earlier the disease can be detected and operated upon, the better the prognosis as regards recurrence, and in a large number of cases the disease can be diagnosticated at a time before glandular infection has taken place; and if the tumor can be removed within six months from its incipiency, and the axillaiy glands and fatty tissue can be dissecti^l out, and likewise the pectoral fascia and the peri-mammary and para-mammary areolar tissue, the prognosis will yiekl brilliant results." Wide infiltration of the skin, extensive adhesion to the pectoral muscle or to the thoracic parietes, very large 400 MEDICAL AND SURGKUL GYNJICOLOGY. axillary glands or enlarged mediastinal glands, or involve- ment of the supraclavicular glands, all tend to contra- indicate operation with the hope of giving permanent relief, but even in such, excituon of the breast and axillary glands may at times be undertaken for the relief of the local symptoms, and the prolongation of life. In undertaking an operation for the eradication of this disease, no partial one should be performed. The rule must be, excise wide of all affected tissues, remembering that there is an area of affected tissue out- side those portions visibly affected. In all cases it is necessary, too, to open up the axilla and eradicate the glands and axillary fat. Further it is advisable in all cases to remove the fascia covering the pectoralis major, for it is in this fascia that the lymphatics lie which trans- port the epithelial cells from the primary growth to their secondarj^ seats of growth in the axilla. If the pectoralis major muscle be involved superficially, the muscle must be completely excised. One should not cut into the tumor and then use the same knife, without careful sterilization, to make further incisions. It is the epithe- lial cells of the growth from which growth occurs, and the opening up of the tumor and after use of the knife might transfer these cells to the wound surface, where, under favorable conditions, they would grow, reproducing the carcinoma. Recurrence of the growth after operation is the great- est danger in carcinoma, and this danger is the greater the later the operation is undertaken, or when the skin is involved, or there is marked glandular involvement. Dennis, carrying out his principles of early operation and wide removal of the breast and lymph tracts, has had a series of brilliant results. In his first series he had forty three per cent of permanent recoveries after the three year limit, with recurrence, either local, in glands, or in bones or viscera, in the remainder. In his last series of cases he DISEASES OP THE BREAST— NEOPLASMS. 401 lins had one death, two local recurrences, and ten perman- ent recoveries, two cases have not yet reached the limit but are yet free from recurrence. No partial op-ration' can claim these results, but it is well perhaps to remember that these cases were, at least, moderately early in their course. With partial or late operation, recurrence is the rule, usually within a few months, either in the scar, in the axilla, or internally. When possible, all recurrences should be immediately excised, as removal holds out the only hope. ihmhhi INDEX. A. Abdomen, examination of, 86 Abdominal hysterectomy, 273 pref,'nancy, S")? Abortion, tubal, ,'<;")!> AbHcesH, tubo-ovarian, 300 intraperitoneal, 316 pelvif3, 312 Abscess of vulvo- vaginal trlands, 138 *' Absorbent cotton, ,52 Acne of vulva, 147 Aflonoma of breast, 389 Adeno-cur<rin()mu of uterus, 287 Adono-sarcoma of breast, 3!)(), 393 Adiposcere in e(;t()piegestation,36() Ala vesportilionis, 13 Albumen water, 97 AI(!oliol in aiiii'sthesia, (57 Allis' inlialer, (i(i Aloes, therapeutic use of, 88, 1 10 Alum, tlierupeutic use of, 81, 92 Amcnorrhoa, 1(17 after oopliore;!tomy, 108 an.emia and chlorosis in, 108 causes of, 108 definition of, 107 delayed puberty, l(t7 diai^nosis of, 1(»9 prinuiry, 107 primary permanent, 107 primary temporary, 107 secondary, 108 symptoms of, 108 treatnuiut of, 102, 109 Ammonium cliloride, 89 Anniulla, 28 Amyl nitrite in ana-sthesia, 68 Amt'sthetics, 62 a.c.e. mixture, 64 administration of, 64 Allis' inhaler, 66 choice of, 63 chloroform for, 66 closed etherization, 6."> Clover's inhaler, 66 Anit'sthetics, ether for, 65 Eemarch's inhaler, 66 examination under, 7(i niortality from, 62 open etli(!ri/.ati()n. 6.'> Ormsby's inhaler, 66 Anal fascia, 36 Anal region, .38 Anatomy of |)elvic organs, 16 of breast, 380 Andro{;yno, 133 Angioma, urethral, 142 Anode, 101 Antellexion of uterus, 243 causes of, 244 symptoms of, 24r> treatment of, 245 Antoversion of uterus, 242 causes of, 242 ofrerative measures for, 243 symptoms of, 242 treatment of, 243 Antisepsis, 43 Apiol, no, I IT) Appendi(;itis, diagnosis from pelvic; inflannnation, 316 Areolar hyperplasia of uterus, 235 Aristol, 92 Arsenic, therapeutic use of, II 1 1,") Ascites, diagnosis from ovarian cyst, 346 Ase))sis, 43, 45 Atresia of vagina, 127 of uterus, 21 1, 23!( Axillary glands, anatomy of, 380 in cancer of breast, 397 B. Bacillus coli commurn's, 43 Bacteria, pyogenic, 41 Balsam I'eru, 92 Bandages, 52 Bartholin's glands, 19 inflammation of, 146 Bassini's ojHsratioii, 134 Baths, hot, local, sitz, 90 404 INDEX. BiittoricH, Kivlviiiiic, fiiriuli( , 101 Boef ten after o|KMati()iiH, i(7 Bollmionim, !»'i, llH, 125 Bladdor, anatomy of, 32 nal(!uli of, 205 oystoHcopicr oxaminatioii of, H"> digital (ixamiiiatioii of, H3 (loiil)le, 111") exploration of, S3 exMtrophy of, IHr) HBHine of, lJir> foreiffn ImdicH in, 205 intlamniation of, 2(HI injectionn into, 1>3 lif^aments of, 32 tnulforniabiotiH of, 195 neoplasms of, 200 ojHJiiings into, 32 jKJsition for oystoHcopy, 85 relations of, 32 trif^one of, 32 Blazius'o|ieration for vesico- vaginal fistula, IS8 Boranic aoi<l, 45, 54, 92 Boring cancer of uterus, 277 Bozeman's operation for vesico- vaginal fistula, IMS Bre^vst, anatomy of, 3S1 blood supply of, 380 diseases of, 381 diseases of the nip[)le, 382 lymphatics of, 380 malformations of, 382 nerves of, 381 neuroses of, 383 Breast, inflammation of, 383 abscess of, 384 acute mastitis, 383 chronic mastitis, 385 cysts of, 387 Breast, neoplasms of, 388 adeno-sarcoma of, 394 adenoma of, 389 civrcinoma of, 394 classificaticn of, 388 colloid carcinoma of, 398 cystic adenoma of, 390 cystic sarcoma of, 393 encephaloid carcinoma of, 398 fibro-adenoma of, 390 papillary cystoma of, 390 proliferous cysts of, 300 sarcoma of, 393 scirrlius of, 396 Broad ligament, cysts of, 339 contents of, 340 incomplete o|K3ration in, 354 removal of, 353 unilo(;ular, 340 Broad ligament, thrombus of, 36fi C. C'alcification in ectopic gestation, 3(iO Calcium chloride, 89 Cahuilus of bladtler, 205 Calomel, 88 Canal of Nuck, 2(5 Cancer, etl'ects onmenstruaMon, 108 Cannabis indica, 89, 118 (Jantharides, 91 (Jarbolic acid, 44, 92, 124, 146 ('arcinoma of bladder, 206 of cervix uteri. 278 encephaloid, of uterus, 278 of ovary, 355 Carcinoma of breast. 394 colloid, 398 columnar-(!elle<l, 398 duct, 398 encephaloid, 398 scirrhus, 396 prognosis of, 399 spheroidal-celled, .394 squamous-celled, .394 treatment of, 399 Caruncle, urethral, 142 Caruncuhi myrtiformis, 21 Cascara sag!'ada, 88 Catheter, Kelly's ureteral, 85 Mott's double current, 93 Cathode, 101 Cauliflower cancer, 277 (Jervical canal, dilatation of, 81 stenosis of, 103 Cervix, amputation of, 238, 282 ('ervix, cancer of, 277 amputation of cervix for, 282 causes of, 1:77 diagnosis of, 280 extension of, 278 hysterectomy for, 282, 286 jwilliative treatment for, 286 pathology of, 277 symptoms of, 279 treatment of, 281 varieties of, 277 Cervix, congenital auresia of, 211 INDEX. 405 Cervix, cyHtM of, '_'«! cyntio doj^oiienitioii of, "J-J? ectropion of, 22ti (/'ervix, oronioii of, •2'24, 22U follicular, 2'.>» papilliiry, 220 Himple, 225 Cervix, lacoriitioti of, 213 8arconiii of, 290 Chloroform, adiniiiiHtration of, 66 syinptoniM of dfinger in, 67 treatment of dangerous synip- tomw, 67 Chloral hydrate, 1 18 Chlorosis and anainia, 108, 112, 116, 130 Cimicifiiga, 110, 117, 131 Clitoris, anatomy of, 18 malformations of, 132 Clitorideotomy, 129 Cocaine, 92 Cocjcygodynia, 1.")! Coccyx, excision of, 152 Cci'liotomy, 271 abdominal incision in, 271 closure of abdominal incision in. 272 for genital tubercidosis, 377 for pelvic ha-matocele, .368 methods of suture in, 272 Clover's crutch, 1,)8 inhaler, 66 Cold, application of, 90 Colloid carcinoma, 398 Colpitis, 177 Colpo-cleisis, 191 Colpo-perineorrhaphy, 167 Colporrhaphy, 157 anterior, 157 Hegar's method, 158 Lefort's operation, 159 position for, 159 Sims' method, 157 Stoltz's method, 159 Commissures, 17, 18 Condylomata of vulva, 139 Connective tissue of pelvis, ,36 Constipation, jiost operative, 98 Copper sulphate, 92, 146 Corpus cavernosum, 18 Corpus luteum, 31 Corrosive sublimate, 44 Corpus uteri, cancer of, 287 diagnosis of, 288 Corpus uteri, cancer of, treatment, 289 varieties of, 287 Cracked nipples, 382 ('urettoM, 83, 94 Curetting, 94 Cystitis, 201 a(nite, 200 causes of, 200 chronic, 200 Emmet's button-hole oiKsration for, 205 operative treatment for, 205 pathology of, 200 symptoms of, 201 treatment of, 202, 204 Cystocele, 155 causes of, 1,55, 256 complication?, of, 156 treatment of, 1;.;!, 171 Cysto-sarcoma of bre.st, 3!)3 of uterus, 29(t Cystoscope, 85, 189 Cysts of the breast, .387 retention, 387 serous, 387 treatment of, 388 Cysts of cervical canal, 261 of vagina, 182 of vulvo-vaginal glands, 1.38 Cysts of ovary, 331 dermoid, 337 follicular, .3.S1 glandular proliferating, 333 papillary proliferating, 336 parovarian, .339 supra-tubal, 332 tubo-ovarian, 331 O. Depressor, vaginal, 79 Diabetes, effects on menstruation, 108 Diagnotfis in general, 68 Dietary, post operative, 97 Digitalis. 68, 112 Dilators, uterine, 82 Ellinger's, 82 glass, 129 (ioodelKe, 82 Hanks', 82 VVylie's, 82 Diplococcus pneumoniie, 42 Discus proliferus, 30 im INDEX. Diseusf of special rej^ioiiH, 132 Disiiifc^ction, (^liomiciil, 44 of Held of opei'iitioii, 47 of hands, 4") Dorsal position, 76 Douthes, 90, 91 iiitra-tifceriiie, 93 Douglas' potu^h, 34 Drainage, iodoform gauze for, 53 nietliods for, r)3 reasons for, '}'3 tubes, 53 Dressings, 51 preparation of, 52 Dj'snienorrho'a, 1 1'l Dysmenorrhd'a, e,,'igeHtive or in- Hanimatory, 118 causes of, 119 definition of, 118 iliagnosis of, 1 19 symptoms of, 1 19 tieatment of, 120 Dysnienorrhiea, ineuibraiious, 122 character of disiiharge in, 122 chfira(!ter of pain in, 123 curetting in, 124 diagnosis of, from early abortion, 123 dilatation of cervix for, 124 galvanization for, 1(13, 124 menstrual decidua in, 122 microscopical examination in, 122 pathology of, 122 symptoms of, 123 treatment of, 124 Dysmenorrliu'a, neuralgic. iKi causes of, 1 1(5 definition of, IKi symptoms of, 1 17 treatment of, 1 17 use of drugs in, 1 17 Dysmenorrhd'a, obstru('tive, 120 causes of, 121 character of pain in, 12! dihitation of cervix in, 122 flexions as a cause, 121 pin-iiole OS as a cause, 121 poh ,.>! and fibroids as causes, 121 . symptoms ot, 121 treatment of, 122 use of stem pessary i!i, 122 DysineiiorrlKt'a, ovarian, 124 I)ysmenorrh(pa, ovarian, causes of, 124 dironic ovaritis in, 124 prolapse of ovary in, 124 treatment of, 124 Dj'smenorrhd'a, treatment of mixed form, 126 Dyspareunia, 73, 127 Ectopic gestation, 35(1 abdominal, 358 ampullar, 357 changes in fatus after death in, 360 classification, 357 diagnosis of, 362 etiology of, 356 evai.aation of gestation sac through vagina, 356 interstitial, 357 life of foetus in, 359 operation for, 364 primary, 357 rupture of sa(! in, 357, 361 secondary, 357 symjjtoms of, 360 tubal, 358 treatment of, at time of rupture, 363 treatment of, before ru[)ture,362 Fctropion of cervix uteri, 215, 226 Kczcnia of vulva, 147 diagnosis from herpes, 148 Electricity, a|>i)li(;ation of, 100 articles necessary for, 101 faradic, or indirect current, 102 galvanic, or direct current, 101 Electrodes, lOl Apostoli's, 101 bipolar, 101 Engelman's, 101 large and small, 102 Martin's, 101 thera|ieutic ett'ectsof, 103 Elepliantiasis of vulva, 140 Elytritis, 177 Elytrorrhajjhy, 157 Enuiiet's button -hole oj)eration, 205 operation for fecal fistula, 193 perineorrhaphy, 1()9 tiachelorrhaphy needles, 217 Encephaloid carcinonui, 398 Endocervicitis, 224 INDEX. 407 Kndocervioiti.s, cdiise.f of, •J.'J.'t cystic (legenenitioii in, 227 cliagii(),si.>< of, 227 eversion or ectio|)ioii in, 22(i folliciilfir eroHion in, 22(5 lociil jippliuatioiis for, 228 opyrutive treatment for, 229 I)apilliiiy erosion in, 226 patholof^y of, 22o symptoms of, 227 treatment of, 227 Ehflometritis, acute, 219 associated with metritis, 219,221 causes of, 220 diajrnosis of, 222 follow inir abortion or labor, 222 hysterectomy for, 223 pathology of, 220 prognosis of, 222 septic infection in, 222 streptococcus antitoxine in, 224 symiitonis of, 221 treatment of, 223 treatment of septic form, 223 Eulometritis, chronic corporeal, 229 causes of, 230 diagnosis of, 233 glandular, 230 interstitial, 230 pathology of, 230 I)hysical signs of, 233 I)rognosis of, 233 symptoms of, 232 treatment of, 104, llf), 234 Endometritis decidualis, 231 Endoscope, .Skene's, 83 Enterocele, lot! causes of, Irili formation of, 153, 155 treatment of, 156, 171 Epispadias, 132 Episio-cleisis, 191 E|)ithelioma of bladder, 206 of breast, 394 of ovary, 354 of uterus, 278, 287 atypical, of cervix, 278 cylindrical, of cervix, 278 pavement, of cervix, 278 Hcjuamous, of cervix, 278 Erect position for physical exam- ination, 76 Ergot, tiierapeutic use of, 88, 113 Eruptive diseases of vulva, 147 Eryt.'iema of vulva, 147 Er^'sipelas of vulva, 147 Esmarch's inhaler, (>" Etiology of diseases of women, 57 airest of development, 57 bacteria] a(;tion, 57 congenital doticiencies, 57 constitutional defects, 59 education, 60 infectious diseases, 61 operative causes, 62 sexual exhaustion, 61 Ether, ad'.iinistration of, 65 danger.ri of, 66 treatment of dangerous symp- toms, 67 Examination, form for recording, 69 Examination of natient, (»8 abnormal varieties of menstrua- tion in, 72, 74 history of patient 'n, 70 menstrual history in, 70 obstetric history in, 72 physical examination, 75 tumors and swellings in, 74 urinary and intestinal symjitoms in, 75 Examination, methods of, 77 bimanual, 78 digital, 77 instrumental, 78 rectal, 78 vaginal, 77 visual, 77 Examination, position for, 7G dorsal, 76 erect, 76 genu-pectoral, 76 Sims', 76 Treiidelenlwrg, 76 Exanthenmta, etl'ects of, 61, 112 Exstrophy of bladder, 195 Extra-peritoneal ha'inatocele, 365 Extra-uterine pregnancy, 365 F. Fallopian tubes, 28 ampulla of, 28 developuient of, 14 diseases of, 292 fimbria' of, 28 limbria ovurica of, 28 408 INDEX. Fallopian tubes, infundibulutn of, 28 isthmus of, 28 malformations of, 292 ostium abdominale of, 28 ostium internum of, 28 structure of, 29 Fallopian tubes, inflammation of, 292 acute catarrhal, 293 acute purulent, 293 atrophy of, 306 hydrosalpinx, 304 interstitial salpingitis, 294 prognosis of, 298 pyosalpinx, 302 salpingo-oophorectomy for, 300 symptoms of, 295 treatment of, 299 tubo-ovarian abscess, 306 Faradism, 102 Fascia, anal, 36 deep perineal, 38 ischio-rectal, 36 obturator, 36 [»elvic, 36 perineal, 38 rectovesical, 36 Fibro-adenoma of breast, 390 Fibro-myoma of uterus, 261 Fibro-sarcoma of uterus, 289 Fibroids of uterus, 261 alterations and degenerations in, 265 course of, 266 ■ diagnosis of, 267, 347 etiology of, 265 hysterectomy for, 271 ligature of uterine arteries for, 269 myomectomy for, 271 oophorectomy for, 270 structure of, 263 trf itment of, 105, 268 UP J of ergjt in, 268 varieties of, 262 Fibroma of bladder, 206 of ovary, 354 of vagina, 183 of vulva, 140 Fistula, fecal, 192 causes of, 192 operative relief for, 193 situation of, 192 Fistula, fecal, symptoms of, 192 treatment of, 192 varieties of, 192 Fistula, genital, 184 causes of, 184 definition of, 184 varieties of, 184 Fistula, urethrovaginal, 188 Fistula, uretero-vaginal, 189 causes of, 189 ca'liotomy for, 190 cystoscopic examination in, 189 implantation of ureter for, 190 situa*^ion of, 189 vaginal operations for, 190 Fistula, urinary, indirect methods for relief of, 191 Fistula vesicouterine, 188 diagnosis of, 188 location of, 188 treatment of, 188 Fistula, vesi CO- utero- vaginal, 189 Fistula, vesico- vaginal, 184 Blazius' o{)eration for, 188 Bozeman's o{)eration for, 188 causes of, 184 detection of, 185 location of, 184 Simon's oj)eration for, 188 Sims' operation for, 186 Tait's operation for, 188 Follicular oophoritis, 326 Form for case taking, 69 Fossa navicularis, 18 Fourchette, 18 Frenum clitoridis, 18 Functional diseases, 107 G. Galvanism, 101 thera{>eutic effects of, 102 (ialvanometer, 101 Gastrotomy, 2V1 Gauzes, 52 (Jehrung's j)essary, 240 (Jenital cord, 14 Genital fistulaj, 184 (ienital folds, 15 Genital tubercle, 15 (ienital tuberculosis, 371 diagnosis of, 375 etiology of, 371 of ovaries, 374 primary, 371 INDEX. 409 Oenital tuberculosis, proytiosis of, 376 secondary, 371 symptoms of, 374 treatment of, 376 of tubes, 373 of uterus, 372 of vagina, 372 of vulva, 371 Genitals, development of, 12 anatomy of, 16 Genu-pectoral position, 76 (terminal spot, 31 (Jerminal vesicle, 31 Olands, axillary, anatomy of, 380 in cancer of breas^, 397 Glans clitoridis, 18 Glycerine, 91 Gonococcus, 42 Gonorrhtta, 127 Gonorrhreal vulvitis, 145 diagnosis of, 145 treatment of, 146 Goodell's dilator, 82 Gossypium, 89 Gout, effects on menstruation, 116 (iuaiacum, 110, 117 Gynandria, 133 Gynecological techni(|ue, 40 H. Hands, disinfection of, 45 Hank's dilator, 82 Hamamelis, 89, 113 Hiumatocele of canal of Nuck, 135 pelvic, 365 pudendal, 136 Hiematocolpos, 171, 175 dangers from, 172 mode of formation of, 171 symptoms of, 172 treatment o*^, 173 Hajmatoma of ovaries, 324 pelvic, 369 of round ligament, 135 Hiematometra, 172, 175 dangers from, 172 definition of, 172 diagnosis from ovarian cyst, 347 mode of formation, 172 symptoms of, 172 treatment of, 173 Ha'matosalpinx, 172, 305 diagnosis of, 308 HjL'mat()8aii)inx, sym[)toms of, 307 treatment of, 308 varieties of, 305 Heat, external application of, 90 Hemaphrodism, 133 androgyne, 133 gynanclria, 133 treatment of, 134 true and spurious, 133 Hemorrhage, post operative, 99 symptoms of, 99 treatment of, 99 Hemorrhage, pudendal, 136 Hernia, inguino-labial, 134 diagnosis of, 134 radical operation for, 134 situation of, 134 treatment of, 134 Hernia, vaginolabial, 134 method of production, 134 situation of, 134 treatment of, 134 Hernia, vulvar, 134 varieties of, 134 Hegar's anterior colporrhaphy, 158 colpo-perineorrhaphy, 167 method of amputation of cervix, 241 Herjies progenitalif, 148 diagnosis from chancre, 148 diagnosis from eczema, 148 treatment of, 148 Hydatid of Morgagni, cysts of, 331 Hydrastis Canadensis, 89, 131 Hydrocele, 135 diagnosis from hernia, 135 situation of, 135 treatment of, 135 Hydronephrosis, diagnosis from ovarian cysts, 347 Hygiene, general, 87 Hydrosalpinx, 304 diagnosis of, 308 pathology of, 304 symptoms of, 307 treatment of, 308 Hymen, absence of, 171 anatomy of, 21 Hymen, atresia of, 171 dangers arising from, 173 diagnosis of, 172 hicmatocolpos from, 171 ha'inatometra from, 172 hivmatosalpinx from, 172 410 INuEX. \ Hymen, atresia of, symptoms of, 172 treatment of, 173 Hymen, imperforate, 171 malformations of, 171 varietiep of, 20, 171 Hyijenimia of ovary, 324 Hypentsthesia of vulva, 150 pathology of, loO treatment of, 151 Hyijertrophy of uterus, 240 Hysterectomy, abdominal, 273 complete, 276 extra-peritoneal treatment of the stump in, 274 indications for, 273 intra-peritoneal treatment of the stump in, 275 partial, 273 varieties of, 273 Hysterectomj', vaginal, 286 by clamps, 285 by ligatures, 283 Hysterectomy sacral, 286 Hysteropexy abdominal, 253 vaginal, 2o2 I. Ichthyol, 91, 92 Infundibulum, 28 Injuries of vulva, 136 Instruments, list of, 55 for cii'liotoniy, 55 for dilatation of cervix and cur- etting, 56 for operations outside of hospi- tals, 56 for trachelorrhaphy, 56 for perineorrhaphy, 55 for vaginal hysterectomy, 55 Interfollicular oophoritis, 326 Interstitial oophoritis, 326 Intra-ligamentous fibroma of uter- us, 262 Intra-{)eritoneal hfumatocele, 365 Introductory, 9 Inversion of uterus, 257 causes of, 258 diagnosis of, 258 instrumental treatment of, 260 manual treatment of, 259 operative treatment of, 260 symptoms of, 258 varieties of, ' '7 - - . Iodine, 90, 92 Iron, thera|jeutic use of, 110, 117 in amenorrhua, 110 in monorrhagia, 115 in metrorrhagia, 115 in neuralgic dysmenorrhd-a, 117 Iodoform gauze, prejMiration of, 52 powder, 54 Irrigating fluids, 53 normal salt solution, 54 selection of, 54 temperature of, 54 Irrigation during operations, 53 of bladder, 93 of uterus, 93 K. Kangaroo tendon, 51 Kelly's method for examination of bladder, 85 for ureteral catheterization, 85 Koeberle's serre-nu-ud, 273 Kraske's operation for hysterec- tomy, 286 Kraurosis vulvit;, 151 L. Labarracque's solution, 46 Labia majora, structure of, 17 Labia minora, structure of, 18 Laparotomy, 271 Lefort's oi)eration for prolapse of vagina, 159 Leucorrhd'a, 72, 129 appearance of discharge, 130 etiology, 130 idiopathic, 130 symptoms of, 130 symptomatic, 130 treatment of, 131 Lichen of vulva, 147 Ligaments, broad, 25 of bladder, 32 ischio-perineal, 38 ovarian, 13, 29 perineal, 38 - round, 25 sacro-sciatic, 16 sacr. iterine, 25 triangular, 38 uterine, 24 -^ vesico-uterine, 24, 32 ' Ligatures, choice of, 48 Liquor folliculi, 30 INDEX. 411 Lithoijedian, 360 Lupus of vulva, 141 Lyniphutice of breast, 380 Lvsol, 92 w. Magnesia sulphate, 88 Malaria, effects on menstruation. 108, 112, 116 Malformations of bladder, 195 of breast, 382 of hymen, 171 of ovaries, 320 of tubes, 292 oi urethra, 194 of Uu'M-us, 207 of vagina, 173 of vulva, 1.32 Malignant deciduoma, 290 peritonitis, 379 Mammary abscess, ,384 cysts, 390 Manganese binoxide. 111 Mastitis, acute, 383 l)athology of, 384 symptoms of, 383 treatment of, 38") Mastitis, chronic, 385 interstitial, 385 pathology of, 386 treatment of, 387 Meatus urinarius, 18, 31 Membrana granulosa, .30 Menopause, 72, 113 Menorrhagia and metrorrhagia, 1 12 action of eigot, digitalis, ham- amelis and hydrastis in, 11 action of iron and arsenic in, 112, 115 causes of, 112 curetting for, 114 definition of, 1 12 galvanization for, 104, 115 treatment of, 113 use of hot water in, 114 use of tampons in, 114 Menstrual decidua, 122 Menstruation, 70 abnormal varieties of, 72 age of commencement of, 71 atteiu'ant symptoms of, 71 daily amount of discharge, 71 delayed, 107, 109 disorders of, 107 Menstruation, duration of flow, 71 precocious, 115 rhythm of flow, 71 vicarious. 111 Mercury bichloride, 44, 91, 146 Mesosalpinx, 13 Mesovarium, 13 Metritis, acute, 219 exanthematous, 219 fungous, 219 granular, 219 gonorrheal, 219 traumatic, 219 post-puerperal, 219 puerperal, 219 ulcerating, 219 Metritis, chronic, 235 etiology of, 235 pathology of, 235 symptoms of, 236 synonyms of, 235 treatment of, 237 Metritis, chronic endometritis, 229 Metrorrhagia, 112 Micrococcus lanceolatus, 42 Milk, post-operative use of, 97 peptonized, 97 Mineral waters, use of, 88 Mens Veneris, structure of, 17 Morphia, post operative use of, 98 Mullerian ducts, 13 Muscle, bulbo-cavernosus, 38 coccygeus, 37 compressor urethra', 31, 39 constrictor vagina-, 19, 39 erector clitoridis, .38 ischio-cavernosus, 38 levator ani, 34, 37 transversus perinei, deep, 39 transversus i)erinei, superficial, 39 sphincter ani, .34 sphincter vagina-, .34, 38 Mummification inectopicirestation 360 Myo-fibroma of uterus, 261 Myoma of bladder, 206 of uterus, 261 of vulva, 140 Myomectomy, 271 N. Nabothian glands, 23, 227 Naphthol, 45 412 INDEX. Neoplasms of bladder, 206 of breast, 3MH of uterus, benign, 2(51 of uterus, malignant, 276 of vagina, 182 Neuralgia, ovarian, 105 {)elvic, 105 Neuralgic dysmenorrhd'a, 116 Neuroma of vulva, 141 Neuroses of breast, 383 Nipple, diseases of, 382 fissures of, 382 inflammation of, 382 Nuok, caiuil of, 26, 135 Nux vomica, 117 Nymphif, 18 Nymphonumia, 128 causes of, 128 definition of, 128 treatment of, 128 O. Obstetric history of patient, 72 Obturator pouch, 35 Oophorectomy, 125, 300, 302 Oophoritis, acute, 326 course of, 327 etiology of, 326 symptoms of, 327 treatment of, 328 Oophoritis, chronic, 328 etiology of, 329 symptoms of, 329 treatment of, 105, 330 Operating suits, 45 Organs cf generation, 17 Ormsby inhaler, 66 Ostium abdominale, 28 internum, 28 Ovarian cysts, 331 abdominal stage of, 343 accidents and complications in, 341 diagnosis of, 345 pedicle in, 341 pelvic stage of, 342 prognosis of, 344 treatment of, 348 Ovaries, at. ,ihy of, 328 cystic degeneration of, 328 Ovaries, cysts of, 331 classification of, 331 etiology of, 339 Ovaries, dermoid cysts of, 337 Ovaries, dermoid cysts of, contents of, 338 mode of origin of, 339 Ovaries, development of, 13 anatomy of, 29 structure of, 29 Ovaries, diseases of, 320 Ovaries, dis{)lacements of, 321 acijuired, 321 congenital, 321 Ovaries, liy[)eriemia and hajmatoma of, 324 etiology of, 325 symptoms of, 325 treatment of, 325 Ovaries, malformations of , 320 neoplasms of, 330 Ovariotomy, 348 accidents during, 352 delivery of cyst in, 349 for broad ligament cysts, 353 history of, 349 incomplete operation in, .i54 methods of operating in, 359 Ovary, cysts of the corpus luteum, 333 cyst of the hvdatid of Morgagni, 332 follicular cysts of, 333 hirge cysts of, 333 microcysts of broad ligament, 332 small residual cysts of, 331 supra-tubal cysts, 332 tubo-ovarian cysts, 333 Ovary, hernia of, 323 varieties of, 323 radical oi)eration for, 324 Ovary, prolapse of, 322 causes ot, 322 diagnosis of, 323 symi)toms of, 323 treatment of, 323 Ovary, jnoliferating glandular cysts of, 333 (contents of, 335 formation of, 334 origin of, 337 Ovary, proliferating papillary cysts of, 336 contents of, 335 formation of, 336 origin of, 337 Ovary, tuberculosis of, 374 INDEX. 418 Ovary, solid tumors of, 354 carcinoma, 3").") epithelioma, 3r)5 fibroma, S'>i treatment of, 355 Ovum, structure of, 39 P. Paget's disease, 394 Papillary cystoma of breast, 390 Pupdloma of bladder, 2(J(5 of vulva, 139 Parametritis, 104, 310 Parametrium, 25, 36 Parasites, cause of pruritus, 149 Para-uterine pouch, 35 Para-vesical pouch, 35 Parenchymatous cancer of uterus. 277 Parenchymatous metritis, 235 Paroophoron, 25, 31 Parovarium, 13, 25, 31 cysts of, 339 Patient, i)reparation of, for opera- tion, 46 Pedicle in ovarian cysts, 351 ligature of, 351 Pelvic abscess, 312 extension of, 312 situation of, 312 treatment of, 312 Pelvic diaphragm, 37 functions of, 37 muscles of, 37 Pelvic floor, anatomy of, 36, 153 functions of, 1.53 lesions of, 1,52, 171 Pelvic floor, causes of weakness of, 153 constitutional, 153 laceration, 154 over distension, 153 senile atrophy, 154 subinvolution, 1,54 Pelvic Hoor, conditions associated with lesions of, 154 cystocele, 155 enterocele, 156 prolai)se of vagina, 155 rectocele, 156 Pelvic floor, treatment of lesions of, 1,56 colporrhaphy in, 157, 1.59 local astringents in, 156 Pelvic floor, treatment of lesions of, perineorrhaphv in, 160 supplementary suppoits in, 156 suigieal methods in, 157, 171 tampons in, 156 Pelvic hii-matocele, 365 causes of, 366 Cd'liotomy for, 3().S diagnosis of, 367 formation of, 366 symptoms of, 36(i termination of, 367 treatment of, 36.S Pelvic ha-matoma, 3(i9 etiology of, 369 pathology of, 3(59 symptoms of, 370 treatment of, 370 Pelvic inflammation, 309 Pelvic lymphangitis, 31(» Pelvic peritonitis, 128, 315 diagnosis of, 318 etiology of, 315 intraperitoneal abscess in 316 pathology of, 316 ' prognosis of, 319 treiitment of, 319 Pelvic peritoneum, .35 Perimetritis, 104, 315 Perineal body, 39, 153 fascia, 38 ligaments, 38 muscles, 38, 1,52 region, 38 Perineorrhapliy, 160 for complete rupture, 163 control of hemorrhage in, 16'' denudation in, 161 Emmet's operation, 169 Hegar's operation, 167 for incomplete rupture, 161 for rui)ture of recto-v;iginal sep- tum, 164 sutuitJi^ in, 162 Tait's operation, 165 Perineum, craise of loss of power of, 153 laceration, 154 ovei' destension, 153 senile atrophy, 1.54 subinvolution, 154 Perineum, laceration of, 160 effects of, 160 varieties of, 160 414 INDEX. Perineum, results of loss of power of, ISf) cystocele, l^H eufcerocele, ITHS prolapse of viiffina.. 155 rectocele, 155 Perineum, blood supply of, 40 functions of, 153 nerve supply of, 40 structure of, S9 Perioophoritis, 315, 326 Perisalinngitis, 315 Peritoneum, pelvic, 35 Peritonitis, tubercular, 346 diagnosis from ovarian cysts, 346 Peri-uterine phlegmon, 310 Permanganate gauze, 52 Phenacetine, 1 18 Phenol, 92 Phlegmonous inflammation of vulva, 137 Phosphorus, 117 Plastic operations, post-operative treatment of, 100 Plethora, effects on menstruation, 1(»S, 116 I Plumbi acetatis, 01, 146 Pole changers, 1(H Poles of battery, 101 Polypoid flbromaof uterus, 262, 270 Polypus, uterine, 261 vaginal, 183 Post-o{jerative treatment, 96 Potassium permanganate, 45, 111, 146 Powder for dressings, 54 Pregnancy, extia-uterine, 356 abdominal, 357 ovarian, 357 tubal, 357 Prepuce, 18 Procidentia uteri, 255 I'rolapsus urethra', 142 Prolapsus uteri, 254 causes of, 255 complications of, 255 symptoms of, 256 treatment of, 256 Pruritus vulvio, 148 causes of, 149 clinical appearance of, 148 [Mithology of, 149 symptoms of, 149 treatment of, 149 Puberty, delayed, 107 Pudendal hn'matocele, 136 Puflendal hemorrhage, 136 Pulsatilla, 110, 118 Purgatives, 87 Pyii-mia, 41 Pyosalpinx, 302 definition of, 302 diagnosis of, 308 l)atiiology of, 303 symptoms of, 307 termination of, 304 treatment of, 308 R. Rectocele, 156 mode of formation, 153, 155, 256 complications of, 156 treatment of, 156, 171 Recto-uterine j)ouch, 35 Rectum, structure of, 34 muscles of, 34 relations of, 34 Retro-ovarian shelves, 35 Resolvents, 90 Restlessness after oi»eration, 98 Retroversion and retroflexion of uterus, 246 causes of, 246 operative treatment for, 252 shortening round ligaments for, 252 symptoms of, 246 treatment of, 249 use of pessaries in, 249 vaginal fixation for, 252 ventral fixation for, 253 Rheophores, 101 Rheostats, 101 Rheumatism, effects on menstrua- tion, 116 Rosenmuller's organ, 13, 21 S. Salicylates, 110 Salicylic acid, 45, 146 Salpingitis, 292 acute catarrhal, 293 acute jHirulent, 293 interstitial, 294 prognosis of, 298 salpingo-oophorectomy for, 300 symptoms of, 295 treatment of, 104, 298 INDEX. 415 Salpiiifro-oophorectomy, 3()0 abdominal, IM) vaginal, 302 Salt solution, normal, 54 Sapni'inia, 41 Saifjonia botryoideM, 290 Sarcoma of breast, Hm of ovary, 355 uteri ileciduo-cellulare, 290 Sarcoma of uterus, 289 diagnosis of, 291 symptoms and course of, 290 treatment of, 291 varieties of, 2S9 Sarcoma of vulva, 141 Schroeder's method for amputation of cervix, 239, 241 Scirrhus of breast, 396 adhesion of skin in, 396 axillary glands, infection in, 397 axillary glands, removal in, 400 pathology of, 39G retraction of nipple in, 396 treatment of, 400 Sedatives, 88 Septicemia, 41 Sepsis, 41 Serre-n(vud, Koeberle's, 273 Tait's. 273 Serum therapy in septic endome- tritis, 224 Sex, diagnosis of, 133 Sexual incompatability, 127 Shock, post-operative, 99 Silk sutures, 48 Silkworm gut, 49 Silver nitrate, 92 Simon's operation for vesico- vaginal fistula, 188 Simpson's sound, 80 Sims' anterior colporrhaphy, 157 operation for vesico- vaginal fistu- la, 186 Skene's endoscope, 83 glands, 32 hawk-bill scissors, 218 Speculum, Burrage's, 93 bivalve, 79 dack-bill, 79 Edebohl's, 217 Ferguson's, 78 vaginal, 78 Sponges, 62 Sponges, bleeching of, 52 gauze, 53 marine, 52 Staflfordshire knot, 352 Staphylococcus citreus, 41 epidermidis ulbus, 41 pyogenes albus, 41 pyogenes aureus, 42 Steriliziition, 43 of catgut, 49 of catgut chromicized, 51 of dressings, 51 by dry heat, 43 of field of o{)eration, 47 fractional, 44 of hands, 45 of instruments, 48 of irrigating fluids, 54 , '■■', ' of kangaroo tendon, 51 Kronig's method of, for catgut, 49 ^ by moist heat, 44 of normal salt solution, 54 of o{)erating trays, 48 of silk, 48 of silkworm gut, 49 of 8{)onges, 52 by steam, 44 of water, 54 Sterility, 125 ac(juired, 127 causes of, 127 congeniuil, 127 definition of, 127 treatment of, 128 Stenosis of cervix, 259 ^ Stolti' method for anterior colpor- rhaphy, 159 Streptococcus antitoxin in septic endometritis, 224 Streptococcus pyogenes, 42 Stryhnine in amesthesia, 68 post-operative use of, 96 Subinvolution and sclerosis of uterus, 235 Submucous fibroma of uterus 262 Subperitoneal fibroma of uterus. 262 Sutures in ca-liotomy, 272 buried, 273 in mass, 272 tier, 273 through and through, 272 41() INDEX. T. Tait'H opoiiitioii for vewco-vaj^iiml fistiilii, ISH |)orine()rrtiii|>liy, 165 Herre-iiii'iitl, 'iT-H TiiiiHK)i>H, !t2 Taiiiiic acid, Stl, 14(i Te(,'l)ni(|ue, gynucoloj^icuil, 40 Telaiigieotatii! inyoma, 'J()4 Therapeutics, gyiiiicological, 8(i hygiene, general, 87 purgatives, 87 resolvents, 90 sedatives, 88 special gyna-cological drugs, 88 tonics, 88 Therapeutics, local, 90 applications to uterus, 92 counter-irritation, 91 curetting, 94 electric currents, 100 external applications, 90 internal applications, 90 intra-uterine injections, 93 {lelvic massage, 9() vesical injections, 93 Tiierapeutics, post-operative, 96 Thiersch's solution, 54 Thirst, treatnient of, after cu'lio- tomy, 97 Thomas' cup pessary, 246 Thrombus of broad ligament, 367 Tonics, 88 Toxaniiia, 41 Tracheitis, 224 Trachelorrhaphy, 216 indications for, 216 ligatures for, 217 nietiiods for operating, 217 needles for, 217 Trendelenberg position, 76 Tiiatigular ligament, 38 Tub; I pregnancy, 358 Tube, .;trophy of, 306 Tuberculo'^is, etiects on menstrua- tion, iM8, 112 Tuberculosis, genital, 371 Tuberculosis of peritoneum, 377 diagnosis of, 379 treatment of, 380 symptoms of, 378 varieties of, 378 Tubes, inHanmiation of, 292 tuberculosis of, 373 Tubo-ovariaii abscess, 306 Tumors of breast, 388 of ovaiy, 330 (if uterus, 261, 276 of vagina, 182 of vulva, 139, 143 Tunica albuginea, 30 fibrosa, 30 propria, 30 Tui'pentine, 91 Tympanites after ojieration, 98 U. Urachus, 14 Ureteral catheter, 85 searcher, 85 Ureteritis, 206 Uret-ero cystoscojjy, 190 Ureters, catheterization of, 85 diseases of, 206 relations of, 33 Urethra, anatomy of, 31 Urethra, atresia of, 194 causes of, 194 surgical treatment of, 195 symptoms of, 194 varieties of, 194 Urethra, dif'efises of, 141, 194 Urethra, granular erosion of, 198 appearance of urethra in, 198 treatment of, 198 Urethra, irritable, 196 causes of, 196 definition of, 196 treatment of, 196 Urethra, malformations of, 194 causes of, 194 Urethra, prolapse of, 142, 199 diagnosis of, 143 treatment of, 143 Urethra, stricture of, 198 causes of, 198 treatment of, 198 Urethrtd caruncle, 141, 199 situation of, 141 structure of, 141 8ym[)tom8 and appearance of, 142 treatment of, 142 Urethral dilator, 84 speculum and obturator, 84 Urethral venous angioma, 142, 199 diagnosis of, 142 Urethritis, 196 acute, 196 INDEX. 417 UrefchritiH, chronic, l)»7 (lefitijtioii of, I'Hi (liatfnoHiM of, 107 Konoriho'ul, I4r,, ISO, H)7 H.VtnptoniH of, 197 treiitiiiciit of, 1!»S Urethiocclo, |j)il (!oinpli(;iU.ioiis of, i!))» foriimlioii of, l!><j HyniptoinH of, IJ«> treatment of, MM» Urinary fintulic, IH4 Urinary oifranw, anatomy of, 31 Uro-geiiittil rej-ion, 88 Urogenital MinnK, 14 Uterine dreHHing fon;ei)8, 81 sound, 80 Utero-abdominnl pouch, 3;"> UteruH, anatomy of, 21 Uterus, atresia of, accjuired, iJSO Uterus, atresia of, congenital, 211 diagnosis of, 21 1 definition of, 21 1 sym|»toms produced by, 171, 172. 211 treatment of, 211 Uterus, applications to, 92 blood supply of., 27 cancer of, 276 Uterr cancer of body, 287 syi .ptoms and diagnosis of, 288 treatment of, 289 varieties of, 287 Uterus, cancer of cervix, 277 abdominal hysteiectomy for, 282 palliative treatment for, 28(5 pathology of, 277 radical treatment for, 281 symptoms of, 279 vaginal hysterectomy for, 282 Uterus, diseases of, 207 Uterus, displacements of, 241 anteflexion, 24,3 anteversion, 242 inversion, 257 latero-flexions, 25,3 laiero-versions, 2.'53 retroversion and retroflexioi. 246 Uterus, examination of, 81 Uterus, fibroid tumors of, 261 diagnosis of, 267 degenerations in, 265 etiology of, 265 hysterectomy for, 273 Uterus, fibroid tumors of, intor stitial, 2(i2 intraligamentous, 2(i3 myomectomy for, 271 Dophoreitomy for, 270 polypoid, 262 structure of, 263 submucous, 2(i2 subjwritonoal, 262 Uterus, glandular polypus of, 261 Uterus, hypertrophy of, 240 Uterus, intlanunation of, 219 acute endometritis, 219 a<'ute metritis, 219 chronic corporeal endometritis. 229 chronic endocervicitis, 224 Uterus, injuries of, 213 Uterus, accidental puncture of, 213 treatment of, 213 Uterus, lacuration of cervix, 213 causes of, 213 digital examination in, 216 examination by speculum in, 216 o{)er:itive treatment for, 216 pathological changes in, 214 symptoms of, 215 varieties of, 213 Uterus, ligaments of, 24 Uterus, malformations of, 207 absence of, 208 bicornis, 209 causes of, 207 congenitally atrophic, 212 diagnosis of, 210 didelpliys, 210 frt'tal, 212 infantile, 212 septus, 210 subseptus, 210 unicornis, 209 Uterus, nerve su|)ply of, 27 neopiafmo of, 261 position of, 24 Uterus, sarcoma of, 289 diagnosis of, 291 diflusfc, 290 fibro-sarcoma, 289 sarcoma botryoiden, 290 symptoms of, 290 treatment of, 291 Uterus, sclerosis of, 2.35 stenosis of, 239 structure of, 23 418 INDEX. UteruM, nubinvolution of, 103, 235 HiipiKirtin^ npiMvratii8 of, 24 Uttiru8, tuboruuioHiH of, 372 V. Vagina, anatomy of, 19 ^^agina, uppliRutionH to, 91 arreHt of developnioiit of, 174 V'agiiia, atresia and HteiioHi8 of, 173 <!au8e8 of, 174 complete and incomplete, 174 (lutinition of, 174 oHects of. 17r) physical examination in, 17r> surgical nietho<ls for relief of, 176 Hyirptoms of, 17«'» treatment of, 175 Vagina, blotnl supply of, 21 Vagina, carcinoma of, I S3, 27S pathology of, 1S3 symptoms and treatment of, 183 Vagina, cyats of, 182 diagnosiH of, 182 patTiology of, 182 treatment of, 1 82 Vagina, development of, 14, 174 diseaHes of, 171 double, 17.'» tibroma of, 183 fornicet* of, 19 malformations of, 173 mucous ])olypi of. 183 neopla.sms of, 182 ocdu.sion of, 175 Vagina, prolapse of, 155 acute, 155 causes of, 15.5 chronic!, 155 methods of production of, 153, 155 treatment of, 156, 171 Vagina, structure of, 21 tuberculosis of, 372 Vaginal fixation of uterus, 262 Vaginal hysterectomy, 282 by clamps, 285 by ligatures, 283 Vaginal hyatero{)exy. Vaginismus, 129 causes of, 129 definition of, 1. treatment of, 12s» Vaginitis, 177 acute, 177 Vaginitis, adhesive, 179 aphthous, 179 (jlironic!, 180 cystic, 179 definition of, 177 diagnosis of, 180 emphysematous, 179 etiology of, 178 gcmorrlKi-al, 145, 178, 180 granular, 179 pathology of, 178 primary, 177 secondary, 177, 179 simple, 178 symptoms of, 179 treatment of, 181 varieties of, 177 vesicular, 179 Varicose tumors of vulva, 141 VegeUitive cancer, 277 Ventral fixation of uterus, 2,53 Vesical calculus, 205 Vesico-hystero-cleisis, 189 Vestibule, 18 formation of, 15 Vestibulo-vaginul glands, 18 Viburninn pnmifolium, 89, 118 Vitelline membrane, 'M VitelluH, 31 Vomiting, |K)8t-o|)erative, 100 Vulsellum, 81 Vulva, 17 development of, 15 diseases of, 132 Vulva, eruptive diseases of, 147 acne, 148 eczema, 147 erysiiielas, 148 erythema, 148 herjws progeni talis, 148 lichen, 147 prurigo, 147 Vulva, Tuematocele of, 1.35 hii'matoma of, 135 hernia of, 134 hydrocele of, 135 hy{)era'stlieaia of, 150 inrtammation of, 143 kraurosis of, 151 Vulva, malformations of, 132 absence of, 132 absence of labia in, 133 absence of clitoris in, 132 adherent prepuce in, 132 INDEX. 419 Vulvn, iimlfortniitioriH of, enisiwi- fliafl, 132 hemaphrodiHrn, 1.S2 hyjHWfMMlias, i;J2 Vulva, plih^jrrnonous inflammation of, 137 pruritus of, 148 pudendal lia-niatocelo, I3(J pudendal lieniorrliago, !36 tuberculosis of, 371 Vi iva, tumors of, 1.39 condylomata, I3«> <ilci)lmMti,isiM, 140 fibromata, 14(1 liponiata, 140 inyomatu, 140 myxomata, 140 neuromata, 141 papillomata, 13!) r>rolapsuM uretlira-, 142 urethral earunele, 141 urethral venon.s ani'lonui, 142 Vulvitis. 143 clasHifioatii of, 143 diai,'nosis ol 14,') diphtheritic, 144 follicidar, 144 \ ulvitis, gangrenous, 147 gonorrh<i"al, 145 {ihlogmonous, 144 purulent, 144 simple, 143 symptoms of, 144 trwitment of, 1 46 Vulvo-vaginal glands, 19 Vulvo- vaginal glands, abscess of, cysts of, 1.38 W. Water, warm, use of, 113, 118, 124 12.'5, 126 Water, sterile, 54 thera{)eutic effects of, 90, 91 Whites, 129 White line, .36 Wolffian body, 12 Wolffian ducts, 12 Wylie's dilator, 82 Z. Zona pellupida, 30 Zinc chloride, 124 Zinc sulphatf;, 91