!;■ iFE THEORIES X^ RELIGIOUS THOUGHT, LIBRARY BL 240 .B42 Tsfl^^" Beale, Lionel S. 1 Life theori 828-1906 es; their influence upon rel igious LIFE THEORIES: THEIR INFLUENCE UPON RELIGIOUS THOUGHT. " but if I could understand " What you are, root and all, and all in all, " I should know what God and man is." LIFE THEORIES THEIR INFLUENCE rpo\ RELIGIOUS THOUGHT. UONEL S.^BEALE, M.B., F.R.S., Felloiv of the Rnyal Culh^e of Physicians; Physician to King's Collet;e Hospital and formerly Professor of Physiology and of General and Morbid Anatomy in King's College, London. WITH SIX COLOURED TLATES. LONDON: J. & A. CHURCHILL, NEW BURLINGTON STREET. rillLADELI'lIIA, LINDSAY AND BLAKISTON, 1871. [All rights reset- •cii.\ LONDON : HARRISON AND SONS, PRINTERS IN ORDINARY TO IIKR MAJKSTV, ST. martin's lank. PREFACE. In this work I have adduced some of the reasons which have led me to think that the physical doctrine of life is opposed to the development of religious thought and natural theology, and adverse to scien- tific progress. It has not been shown that any one of the physical or chemical hypotheses of life yet proposed rests upon the secure foundation of observation and experiment, while on the other hand the phenomena of living beings, open to the observation of all, not only justify the acceptance of a vital theory, but are only in this way to be accounted for. Although it has been repeatedly affirmed that the non-living passes by insensible gradations into the living, no example of matter in the supposed transi- tional condition has yet been obtained, while, on the other hand, the facts which lead me to conclude that the difference between the living and the non-living is absolute, have neither been controverted nor explained away. My conclusions are indeed at variance with the views very generally entertained and taught in vi PREFACE. these days, but the truthfulness of the observations upon which they are based, now extending over a period of nearly twenty years, has not been called in question. A portion of the first part of this essay has been printed in the Conteviporary Review for April, 1871, but the argument has since been extended and further illustrated. L. S. B. 61, Grosvenor Sti^eet, May, 1 87 1. TABLE OF CONTENTS. I. Physical Life-theories and Religious Thought. PAGE Religion and Science ... ... ... ... ... ... ... i Premature Concession ... ... ... ... ... ... ... 3 Influence of Views on the nature of Life upon Religious Thought 4 Physical Theory of Life incompatible with Religious Thought ... 9 Life not a consequence of Physical actions only ? ... ... ... 10 Of Power and Force ... ... ... ... .... ... ... 12 Self-constructing Properties of Molecules ... ... ... ... 13 The idea incompatible with the ideas of Providence, Personal Ood, and Christianity ... ... ... ... ... ... ... 14 Failure of attempts to construct Iviving Beings ... ... ... 15 Failure of Analogical Reasoning, Metaphor and Prophecy ... 15 If the Physical Doctrine of Life is accepted, must not the idea of God be given up ?... ... ... ... ... ... ... 18 Advocates of Physical View of Life not active Opponents of Religion ... ... ... ... ... ... ... ... 20 If modern Theories true, a revolution in Religious Belief must occur ... ... ... ... ... ... ... ... 21 Most recent conjectures and fancies concerning the Nature and Origin of Living Beings ... ... ... ... ... ... 22 What has been gained by the Physical Hypothesis of Life ? ... 29 No Physical Theory of Life yet propounded stands the test of careful examination ... ... ... ... ... ... 31 IT. The Theory of Vitality and Religious Thought. Phenomena of Living Matter different from Phenomena of all Non- living Matter ... ... ... ... ... ... ••• ,3^ Of the Two States of Matter in Living Beings 40 viii TABLE OF CONTENTS. PAGE Bioplasm or Living Matter .. ... ... ... ... ... 41 Bioplasm of Cuticular covering of Tongue ... ... ... ... 44 Bone of Kitten and its Bioplasm ... ... ... ... ... 45 Skin of Frog ... ... ... ... ... ... ... ... 46 Of the fine Nerve Fibres ro mid an Artery ... ... ... ... 52 Capillaries and Nerve Fibres, Palate of the Frog ... ... ... 53 Vessels and Nerve Fibres of Mucous Membrane ... ... ... 54 Large Caudate Nerve Cells ... ... ... ... ... ... 54 Cells of the Grey Matter of the convolutions of the Brain ... ... 55 Bioplasm concerned in Mental Nerve-action... ... ... ... 60 Vital Phenomena. Characters of the Bioplasm ... ... ... ... ... ... 63 Nutrition... ... ... ... ... ... .. ... ... 67 Bioplasm in Disease ... ... ... ... ... ... ... 69 Production of Formed Material from Bioplasm ... .. ... 70 Bioplasm and Formed Matter... ... ... ... ... ... 71 Objections to the Idea of a Central Force or Power influencing the whole Organism ... ... ... ... ... .... ... 72 Vital Phenomena and Physical Phenomena of a Different Order ... 77 Vitality 78 Of the Action of the Bioplasm concerned in Mental Action ... 87 On the relation of the Non-living and Living to God ... ... 91 TABLE OF CONTENTS. PLATES. *** The bioplasm, or livinj: matter, which alone takes part in development and formation, is represented red in all these plates; the vessels blue, and the tissue, or formed material, in ordinary black ink. pac;e Plate I. — Cutiatlar covering of papilla of tongue, showing bio- plasm and foniied material of the elementary parts at different ages ... ... ... ... ... ... ... 42 Plate II.— Minute structure of growing bone to illustrate the changes which occur during the fomiation of this tissue, and the important part played by the bioplasts in the process — Portion of skin of frog to show the relation of the various structures to one another, and the bioplasm taking part in the formation of all of them ... ... ... ... ... ... 46 Plate III. — A part of a ganglion, or nen'e-centre, with its bioplasts — Artery, with muscular fibre cells and nerves — Capillary vessel and nerve fibres — The bioplasts of all these textures are represented... ... ... ... ... ... ... ... 5^ Plate IV. — Capillary vessels, with their numerous bioplasts antl nerve-fibres, from the mucous membrane covering the epiglottis of the human subject — Large angular and caudate nerve cells from the spinal cord ... . ... ... ... 54 Plate V. — Nerve cells from the gray matter of the brain of man, sheep, and Guinea-pig, showing Inoplasm, or living matter, and formed material, or ner\'e tissue ... ..- ... ... 5^' Plate VI. — Bioplasm of gray matter of brain of man probably ctjii cerncd in thouHit ... ... ... ... ... ••• ••• { the imagination to "privileged spirits" only, does not indicate a generous or philosophical disposition. 2 6 FACTS BE YOND INVES TIG A TION. Dr. Tyndall's argument against the microscope may be put thus. It is certain that many facts remain undis- covered beyond the microscope Hmit, and if these apocryphal facts were discovered they might justify conclusions different from those already deduced from the facts of observation. In other words, facts which can be demonstrated are of little value or importance, because beyond the limits of investigation may be some unascertained facts which, if they could be discovered, might be found to outweigh the actual facts. It so happens that certain facts already demon- strated by the microscope, but which Dr. Tyndall will not acknowledge, are more than sufficient to controvert the hypothesis he has unfortunately so widely and so energetically taught. These facts of microscope observation and investigation are well known to many observers, and the bearing of them has been explained in language which, though less forcible, is perhaps not less intelligible than that in which the fancy facts of the imagination have been introduced to the public. There are surely few scientific facts likely to be of greater value in the education of young people of both sexes than those elucidated by the aid of the micro- scope, but it unfortunately happens that the general conclusions which the pupil would arrive at from microscope studies would be likely to lead him to reject the physical hypotheses of life, and to convince // yPO THESIS OF E VOL UTION. 2 7 him that these were incompetent to exphiin the facts of observation. In the region beyond the microscope limit, says Dr. T}'ndall, " the poles of the atoms are arranged, that tendency is given to their powers, so that when the poles and powers have free action, and proper stimulus in a suitable environment, the\' determine first the germ, and afterwards the complete organism." My physical knowledge is not sufficient to enable me to understand this, but it may be calculated to convey much real information to the people. Per- haps it is not surprising that one who holds such views should believe, and endeavour to make others accept the doctrine, that ''the human mind itself — emotion, intellect, will, and all their phenomena — were once latent in a fiery cloud." " Many who hold the hypothesis of natural evolution," says Dr. T\ndall, " would probably assent to the position that at the present moment all our philosophy, all our poetry, all our science, all our art — Plato, Shakespeare, Newton, and Da Vinci — ^are potential in the fires of the sun." But probably a long course of training would be in- sufficient to enable any one to assent to this position, unless he had had the advantage of being born a privi- leged spirit. It is very well for authority to exclaim, " Let us reduce, if i^'c can ( !), the visible phenomena of life to mechanical attractions and repulsions," let us cast *'the term 'vital force' from our vocabular)^" 28 NOTHING GAINED BY and so on ; but though he and others have the will to do all this, and full confidence in their prospects of success, the attempt has been so far a failure. Life cannot be reduced to mechanical attractions and re- pulsions, nor can any attractions and repulsions be made to imitate the phenomena of life. Dr. Tyndall may cast any word he pleases from his vocabulary, but it may nevertheless remain in the world's vo- cabulary as long as the thing which it signifies con- tinues to exist. No doubt many scientific men desire above all things that people should believe that life is only physical change, but as they cannot bring forward evidence to convince the reason, they seem to be trying hard to gain assent by the aid of strong assertions, by a little gently expressed contempt for other views, and occasionally by a dexterous effort violently to overwhelm, or silence, or extinguish their opponents by force. The most conspicuous member of this class of "privileged spirits " speaks of a student of natural knowledge as a " microsgopist, ignorant alike of philosophy and biology," and belonging to a college " famous for orthodoxy."* It is desirable to examine very carefully the dogmatic assertions of spirits who consider themselves privileged to employ this mode of gaining converts, and enforcing their own principles. * '* Essays on the Use and Limit of the Imagination in Science," second edition, page 49. PHYSICAL LIFE THEORIES. 29 What has been gained by the Physical Hypothesis of Life ? — For many years past the advocates of various physical doctrines of Hfe have been encouraged in every possible way. A large section of the public, it appears, has desired to be taught such views. The statements have been heartily welcomed by the most advanced writers in the periodical literature of our time, who have hailed vague assertions as brilliant discoveries. The merest shadow which appeared to tell in favour of a material hypothesis has been re- peated, embellished, and forced into notoriety; while researches, in the course of which facts have been discovered which seemed favourable to other hypo- theses, have been rejected with contempt, or ignored. The supporters of physical doctrines of life have assisted one another, fought for one another, and praised one another. They have exhibited such determination, and have employed such strong language, as to intimidate many of those who differ from them. Consequently their views have been but little questioned, and, for the most part, instead of being subjected to searching criticism, have been praised, and in no doubtful terms. Physicists have of late been high in popular favour, and have in fact enjoyed every advantage which the most zealous partisans of a cause could desire. But what have they effected ? What solid advantage has the public gained by their teaching, carried on in the most zealous manner for twenty years ? Have they sue- 30 THE " TIMES'' ON LIFE. ceeded in establishing their principles, or are they likely to succeed in doing so within any reasonable period of time ? Are their conclusions accepted, or their arguments respected by careful thoughtful persons ? I have already endeavoured to reply to some of these questions, but a few words as to the results pro- duced by physical hypotheses may not be out of place here. I need only refer to some observations in a leading article in the leading journal of this country (?) for September 19th, 1870. These will enable us to form some idea of the effects of twenty years' active advocacy of such hypotheses upon the minds even of highly intelligent persons. The " Times " tells the British public that the researches of natural pJiilosopJiers seem to show that all the world, or at least all living things, are nothing but large boxes containing an infinite mmiber of little boxes one zuithin the other, and that the least and tiniest box of all covc- tains the '^ germ!'' Now, if for germ we substitute *' intelligence," and look upon each of the boxes as a new layer of conjecture, successively applied to im- prison more and more securely the understanding, already effectually shut up in box number one, we shall get a not inapt illustration of the influence the new philosophy has had upon the mind of the writer of the article, and possibly also upon the minds of many will- ing and enthralled disciples. Perhaps the writer was the same enthusiast whose words have been quoted PHYSICAL HYPOTHESES. 31 by Dr. Tyndall under the head of " Pros and Cons." " We saw in imagination the victory of conscience and reason, the emancipation of a soul, the new birth of an intelligence," and so on.* Those who attentively study the expositions of the physical school, will find that, instead of facts, hypo- thesis has been piled upon hypothesis, and assertion heaped upon assertion, the whole resting upon a basis of continually shifting assumption. Not even the words and phrases used in enunciating the physical doctrines of vitality are permitted to retain precisely the same meaning throughout one single communica- tion. Confusion succeeds confusion. There is, how- ever, that one idea — that the living and the non-living are one, and are influenced by physical forces only — which ever brightly shines through the mists of the modern nebulous philosophy, and illumines its attendant satellites. This all obey, and around it all revolve. No physical tJicojy of L ifc yet propounded stmids the test of careful exaininatiou. — In my work on " Proto- plasm, or Matter, Life, and Mind," published some months since, I have examined several physical theories of life which have received many advocates, and have * But alas, Icmpora inutottturl Ere seven months have gone, another writer in the "Times" sees fit to complain of the "unscientific enthusiasm " with which Dr. Tyndall had dilated on the use of the imagination in science, and with stem disapprobation ousts the autumnal hymn of praise. 2 2 FALLACIES OF been most warmly supported during the last twenty years. Not one of them., however, is found to stand the test of careful critical analysis. Each breaks down, and completely, upon examination, and the last proposed, and perhaps the most pretentious, is the weakest of them all. Many are so obviously inconsistent with facts known to almost everyone, that it is wonderful such notions should have been .seriously advanced. After reviewing these hypotheses, the critic will be astonished that so many doctrines should have been put forward in so short a time in support of the physical view of life. He is almost forced to conclude that their authors must have had some strong motive for endeavouring to make people believe that a physical hypothesis in some shape or other must be received, and that no other explanation was possible. In their remarks upon vital physics, there is a total absence of that philosophical indifference which distinguishes the same writers when discussing some other matters. As soon as they enter upon the vital question, they assume the tone of the advocate, of the proselytizer, of the zealot, and to such energy everything must yield. They put before the reader only the arguments which seem to tell in favour of the doctrine they teach, and the importance of these is usually much exaggerated. The view must needs be supported by forced similes, overstrained analogies, and metaphors calculated to absorb the atten- tion of the reader, and to interfere with his impartial consideration of the question. Not unfrequently the PHYSICAL IIYPOTIIKSIS. ,, physiciil advocate excites the flagging interest of his pupils by an affirmation, a protest, a prophecy, or a de- claration of his individual infallible conviction and be- lief. Unproven and unprovable assertions have been ad-vanced overand over again, until it becomes tiresome to notice them.^ The fallacy of the crystal argument has been many times exposed during the last hundred years, but there it stands in all its fictitious strength, in the very last work written in favour of the hapless spontaneous generation doctrine. Writers on the physical force side not unfrequently speak with contempt of the views of their opponents, while it is utterly impossible to get them to acknowledge that their own assertions should be subjected to any exa- mination whatever, because, according to them, the physical view only is to be received. Some physical authorities are impatient of criticism, avoid debate, announce their views in sermons, and seem to be unable to distinguish between preaching and teaching. Objec- tions which they cannot answer they afifect to despise ; and, instead of mentioning the terms of the particular objections to which they refer, account opposition * The sun "prepares tlie food which supplies our frames witli energy as well as with that delicate tissue which is essential to our exi>tencc," is an example of the way physicists commonly state the case. They then go on to remark that the sun is a fire, forgetting how incorrect it W(ndd be to talk of a fire " preparing" our dinners or the latter supj)Iying us with nerve and muscle and bone. Physicists should really study the structure and mode of growth of tissues before they talk of their prepa- ration by the sun or speak of the great luminary as a creator. D 34 UNFAIR STATEMENT OF THE " fri\olous." Their plan of treating those who differ from them is Hke that of the boy who throws a stone or two, and then runs away. But if any form of the physical doctrine of life had been proved to be true, or had been shown to be based upon some sort of trustworthy evidence, or had upon careful examination even appeared plausible, it would undoubtedly have been right to have inquired very carefully whether religious views could any longer be considered defencible. No one will deny that belief in any of the fanciful hypotheses of the last ten years is consistent with the display of virtues, called " Christian," though many are doubtful whether the physical doctrine is not inconsistent with a belief in the evidences of Christianity. But it has certainly to be shown that the evidence adduced in favour of physical views of life is strong enough to disturb, ever so slightly, the old foundations of Christian faith. If many of the modern hypotheses concerning the nature of life were true, or even tended towards truth, it must be admitted their influence would be detri- mental to religious thought. Indeed religious thought in the sense in which the term has been generally understood would probably soon be of the past. The advocates of some of these doctrines appear to consider that the fancies they propound are to take the place of religious beliefs, and to supplant them, and are to form the basis of some new relieion of the future. But it is not only as regards views ARGUMENT FOR THYSICAL V] FAV. 3^ concerning the nature of life that modern science aims at taking a very exalted place in human hopes and aspirations, for does not she claim to be able to solve with precision problems the solution of which no form of religion has hitherto ventured to do more than suggest, as it were, vaguely, diffidently, and doubt- fully ? Such, for example, as the mode of origin and formation of the world, the causes of the early changes upon its surface, the origin and nature of all living things, the precise relation of man to other beings, the end of all. Every form of physical hypothesis involves the conviction on the part of its advocate that the evi- dence we possess justifies the belief that the present phenomena of existence are but a consequence of antecedent physical changes, these of others, and so on, as it were, in a chain, link succeeding link, up to the very first, which originated in the beginning. Ikit the evidence hitherto advanced in favour of such a view is most inconclusive. But is it not a fact of profound significance, that nothing whatever has been proved concerning the phy- sical nature of the changes which immediately precede the production of a particle oi secretion or of tissue in any living organism whatever } The changes are said to be molecular, but, what is molecular } and what i)re- cedes the occurrence of the supposed molecular change } Those who pretend to be able to tell us all about our origin from a fiery cloud in a remote past, are unable D 2 36 LAW AND EVOLUTION. to inform us of the nature of the changes occurring in any part of one of the multitudes of Hving beings around us, and Avhich changes are now proceeding from moment to moment under our very eyes. They tell us nothing of what takes place in the matter we can study and investigate, and expect us to receive without question the extravagant assertions they make concerning the changes which occurred in the prime- val mist out of which our planet, with everything upon it, has, according to their statement, been formed. Not only so, but they do their best to sup- press all theorizing and speculation concerning pre- sent life which does not happen to chime in with their dismal fancies concerning the past and future changes of their material molecules, and their melan- choly views about evolution by what they call law^ without any kind of superintending, or willing or de- signing, directing or governing power. THE THEORY OF VITALITY AND RELIGIOUS THOUGHT. fT has been shown that the acceptance of any of the physical theories of life hitherto proposed, would involve the necessity of very serious alterations in our views con- cerning religion, and that if the physical doctrine of vitality could be proved to rest upon any basis of truth, the old foundations of religious thought, which were not completely destroyed, would have to be entirely reconstructed. We have now to consider whether the theory of vitality to which one is led by a careful stud}' of the changes occurring during the development and growth of every kind of living being known, will in an\' way affect the religious beliefs which have been entertained for many centuries by the best and wisest among men. In the first place, it is necessary to state the theory and the grounds on which it rests. The doctrine of vitality, which the results of careful observation have led me to accept, involves the conclusion that living matter of every kind and description, and at every VITAL POWER. period of life, is altogether different in its essential nature from any kind of non-living matter whatever, even so very different that there is a total absence of any analogy between the properties peculiar to the living matter and any properties known in connection with the non-living. The transcendent difference is not due to chemical composition or to physical con- stitution or property, but to the presence and activity of a power which cannot, under any circumstances, be developed from matter that has not been made to live by the influence of that which is already living. My investigations have been conducted in the hope that, from a careful study of the character of the acts performed, I might succeed in drawing an in- ference concerning the nature of the unknown power that effects the wonderful changes which are inex- plicable by any known laws, and cannot be accounted for by any material agencies, properties, or forces. PJienomcna of Living Matter different from Pheno- mena of all Non-livi7ig Matter. — Notwithstanding all that has h^^xv asserted, over and over again, to the con- trary, it has been proved conclusively that the pheno- mena of the simplest living thing are essentially different from those of non-living matter, and cannot be imitated, and that the living does not emanate from the non-living, or pass into it by gradations. Life is no mere sum of ordinary forces, nor does vital action result from material changes alone. It cannot be shown that the matter of the world and its mate- NO N- VITAL PHENOMENA. 39 rial forces necessarily give rise to the development of life. We may, therefore, still regard life as transcend- ing mere matter and its forces — a later gift of an All- Wise Omnipotence. The tiniest speck of living matter exhibits no structure to account for its actions, and it contains no machinery. It belongs to a system altogether dif- ferent from the mechanical world. It is not in the least degree like a clock, for no two of its * ticks ' are alike. Every one of its molecules makes its own wheels and cranks and springs and pendulum, and sets itself going and winds itself up, and makes new clocks, and in a moment, as perfect and as powerful and as strong as the parent, and all this though com- pletely destitute of works or niachincry of any kind. Ahd there are millions of such molecules in the most minute parts of every living organism. Many of them acting in harmony, now tending one wa>', now another ; now appearing to obey gravitation, now moving, and with equal velocity, in defiance of the great law. To compare a living thing witli a clock is, then, misleading, and it is perversely misleading. The molecules of matter that is alive are arranged as they were never before arranged. Elements which ha\'e the strongest affinity for one another arc separated from their combinations, and perhaps made to combine with elements with which they have no natural ten- dency to unite ; and all this is effected, not as we see it done in the laboratory by the skilful chemist after 40 TM^V ST A TES OF MA TTER. prolonged experience and with the aid of complex contrivances, but silently, and, as it were, by a fiat, without any apparatus whatever. Of the Two States of Matter in L iving Beings. — Some years ago, I obtained evidence which convinced me that the substance of the bodies of all things living w^as composed of matter in two states ; and I showed that the truly vital phonomena, nutrition, grozut/i, and multiplication, were manifested by one of the two kinds of matter, while the other was the seat of physical and chemical changes only. From observa- tions I was led to conclude, that of any living thing, but a part of the matter of which it was constituted, w^as really living at any moment. In the case of adult forms of the higher animals and man, indeed only a very small portion of the total quantity 'of their body-matter is alive at any period of existence. These views met with little favour at the time, but have since been accepted by many. The facts upon which my arguments were based have not been dis- turbed by those who are opposed to my views. It has been asserted by some that the distinction be- tween the living and non-living matter of a living being could not be sustained, and by others that such a distinction was of no importance at all, if it could be established. Certain authorities have most positively affirmed that the living differs from the non-living only in degree, and that the non-living passes by gradations into the LIVING AND FORMED. ^j living, but they appeal to the imagination for the facts upon which their assertion is founded. Between the living and the non-living they say there is no essential difference — no difference save in the rate at which the physical and chemical changes are carried on. Any one might as well attempt to prove that the living state and the dead state were different degrees of one and the same state. But the living is not the lifeless, and it has been shown that matter in the former con- dition may be positively distinguished from matter in the latter state, even in the case of extremely minute particles in which living matter and matter that has ceased to live, and matter that is about to live, are associated together within a very small area. Bioplasm or Living Matter. — It must be carefully borne in mind, that the living matter or bioplasm in which wonderful changes occur as long as its life lasts (which changes cannot be explained by physics and chemistry), is not a substance very sparingly distributed, and only occasionally to be separated from the living beings and studied, but it is to be found almost everywhere. It can be examined at any time, and the principal and most remarkable phenomena can be demonstrated with the aid of a -pLj-th of an inch object-glass magnifying 700 dia- meters. There is not a living being \\ hich docs not contain bioplasm, and whose structure, composition, and actions do not depend upon it. There is not at any period of life, in health or in disease, a portion of 42 LIVING MATTER, BIOPLASM. any tissue of man's body the size of a pin's head, with perhaps the single exception of the teeth of the adult and in old age, that does not contain some of this living matter or bioplasm in which purely vital pJienouiciia take place. Nor is there an action cha- racteristic of living beings, at any period of their existence, in which this bioplasm does not play an all-important part. The germ at the earliest period is composed of it almost entirely, and from the original bioplasmic germ-mass results the infinite number of bioplasts which subsequently take part in the formation of the several tissues and organs. Every tissue may be divided anatomically into elementary parts. Each elementary part consists of the living matter or bioplasm^ and the lifeless formed matter (cell-wall, envelope, tissue, intercellular sub- stance, periplastic matter) produced at the moment of the death of the particles of the first. Formed matter accumulates in the tissues as age advances, and thus interferes with the free access of nutrient matter to the bioplasm. As we grow old the proportion of the living to the lifeless matter of the organism becomes less and less, but even in advanced age and in the driest of growing tissues, living matter is still to be demonstrated in considerable amount, and can be discovered in advanced age without difficulty. That I may render tlie facts upon which my con- clusions have been founded clear to the reader, I will PLATE J. CUTICULAR COVERING OF TONGUE. Fi^. 1. Natural size of the apeci- men repre- sented iQ Fii^. 1. Perpeudicular sectiou thiou^h thick layer of epithelium co'.^-iii!;: ili- i ;i| illio oflbe lonlrjr the bioplasm or living matter aud the formed matenil o: part of the figure, the cells which are closest to the u SEFARAIE cEtLs hut the soft formed material forms a ■ bioplasts, and are multiplying When the formed mai'.^rial Laa bioplasm to some extent the process of multiplication ceases, As i the surtace c, to take the place of those removed, the fonned material i the remains of the bioplasm matter die. MagniScd 700 diaiia;;i'-i s . tovrards dry aud .-.V.,-.'^h or ail mc. PREPARATION OF SPECIMENS. 43 ask him to examine attentively the drriwings taken from a few very minute pieces of tissue which have been prepared so as to distinctly show the masses of bioplasm embedded in them, from which they were formed, and by the influence of which their intej^rity was preserved as long as life lasted."^ Every mass of bioplasm of any tissue can be artificially and perma- nently coloured by an ammoniacal solution of car- mine, and thus every particle of living matter in a tissue can be demonstrated very distinctly, and its relative proportion in the same tissue at different ages, accurately determined.! In the following draw- ings, copied from actual specimens, the bioplasm is coloured carmine red, the vessels which were injected with Prussian-blue fluidj, blue, and the tissue or formed material is represented by the ordinary printing ink, because it was not coloured in the preparations. Now, let us picture to ourselves in every part of the tissues of a living thing, even in the solid bone, PI. II, fig. I, and separated from one another by tolerably equal distances, little particles of living matter, often * Many specimens, prepared in this manner, were demonstrated publicly in the Courses of Lectures given by me at the Royal C«jllege of Physicians in i86i, in King's College from 1858 to 1869, and in Oxford, by direction of the Radcliffe Trustees, in 186S-69. For details of the mode of preparation, sec " How to Work with the Microscope," 4th edit., p. 108. t If Mr. Huxley had studied specimens prepared in this manner, his views concerning Protoplasm would probal^ly have been modilicd in very important particulars. X " How to Work with the Microscope,"' pp. 93, 97. 44 BIOPLASM OF CUTICLE. less than the -:^yL._th of an inch in diameter, each separated from its neighbours, and surrounded by the material it has produced. Each living bioplast attracting, through the lifeless matter already formed by it, materials suitable for its nutrition. Each, living, growing, and forming ; each capable of infinite growth, infinite multiplication. Bioplasm of Cuticular Covering of Tongue. — In the first place let us study a minute particle of the tissue which forms the upper free surface of the tongue, in size much less than the head of a very small pin, Plate I, fig. 2, When this is magnified 700 diameters we see the several points represented in Fig. i, pi. I. In every one of those oval masses of bioplasm coloured red, vital phenomena occurred during life. The physicist and chemist are utterly unable to explain the actions going on in the bioplasts, or to tell us exactly what sort of changes occur, or in what way the nutrient matter, taken up from the blood, is changed and some of its elements re-arranged, so that at length is produced the firm tissue on which the physical properties of the texture in question entirely depend. After careful study of such a specimen, we may form a notion of the manner in which the bioplasm divides and subdivides, and becomes resolved into formed material which accumulates upon its surface, and eventually hardens and constitutes an effective protection to the delicate textures which lie beneath BIOPLASM OF BONE. 4^ it. We can also understand how the new elementary parts gradually grow up from beneath and supply the place of the old ones which are cast off from the free surface. But these phenomena cannot be explained by physics and chemistry, or without calling in the aid of the hypothesis of vital power. Bone of Kitten and its Bioplasm. — Next, let us ascertain whether the examination of other tissues in the body teaches us the same general facts. In PI. II, fig. I, p. 46, is represented a small piece of the perma- nent bone with the subjacent soft texture of a kitten at birth. To the left is the delicate growing tissue in which the vessels that have been artificially injected with Prussian-blue are distributed. From the blood circulating in these all the elements entering into the formation of bone are selected. The little bioplasts above c are the agents actively concerned in the operation. These take up nutrient matter, and grow and multiply, and become separated further and further from one another as the delicate tissue which they form increases in the intervals between them. The matrix thus produced afterwards becomes the seat of deposition of calcareous salts, in consequence, probably, of chemical changes, d. The calcareous salts become incorporated with the organic matrix, and the bone formation is complete, e. The process con- tinues, but more slowly, until each little bioplast henceforth drawing its nutrient material through pores (canaliculi), left during the progress of the BIOPLASM OF NERVE. ^y every one of these different tissues are minute masses of living matter or bioplasm. The matter of which the several bioplasts taking part in the formation of all these very different tissues are composed, possesses the same characters, although the several forms of bioplasm produce tissues differing from one another in the most essential particulars. At an earlier period of life, the little tissue-forming bioplasts were situated much nearer to one another. This separation of the bioplasts is a necessary con- sequence of the formation of formed material or tissue, which proceeds, and, as age advances, accumulates in the intervals between the bioplasts. At a still earlier period the bioplasts, which were to take part in the formation of cuticle, nerves, vessels, pigment-cells, fibrous tissue, &c., respectively, were quite close to- gether, or formed part of one bioplasm-mass. It would have been impossible had the tissue been examined at an early period, to determine which was a nerve bioplast, \\\i\QX\ depigment bioplast, and whicli was to take part in the formation of a vessel, or at lengtli to assume the form of a blood corpuscle. But all these bioplasts have descended from a common bioplasmic mass. It is absurd, therefore, to attempt to explain the results, as some have done, by affirming that they are due to differentiation, to molecular c/ianges, or to machiner}', or to physical influences, fur it must be obvious that by these phrases no explanation what- ever is afforded. 48 ''MOLECULAR'' CHANGES. The bioplasm of an advanced tissue cannot be dis- tinguished from embryonic bioplasm any more than the bioplasm of one tissue can be distinguished from that of another. That there must be a vast difference in power is certain, from the very different results which are brought about. The difference between bioplasts is not a difference in physical characters, or in structure, or in chemical properties, nor is it to be expressed in force terms. Physical authorities may assert that the difference is due to some difference in the " molecular changes " which take place, but then we must inquire what occasions the difference 1 More- over, since nothing is known as regards the supposed molecular changes, while the meaning of the term " molecular," as it is employed here, cannot be de- fined, it is obvious that the announcement amounts to absolutely nothing more than the admission that a change occurs, but that nothing whatever is known to physicists concerning its nature, and nothing is known of the circumstance^ which determine its occurrence. No one who studies such a tissue as this will feel at all satisfied with the manner in which its descrip- tion is dismissed by many of those who have not the patience or inclination to pursue microscopical inves- tigation, and who endeavour to prejudice persons against minute inquiries and the facts which have been demonstrated thereby.* * The most positive assertions have been made concerning facts only to be demonstrated and understood by those who have made themselves A NERVE CENTRE, 4^ It is very significant that no attempt is made by- philosophers who discourse on the origin and destina- tion of Hving beings and of the world they inhabit, to account for the wonderful arrangement of one of the very many textures of a living thing, and of the intimate relationship they bear to one another, or for their exquisite and orderly adaptation by which excellence of action and perfect fulfilment of the objects of their formation are ensured. A nerve centre is represented in Fig. i, pi. III. The little oval bodies embedded in it are the nerve cells^ from each of which two or more delicate nerve fibres extend, or have been drawn out during the growth of the tissue. These nerve fibres run between contigu- ous cells and seem to surround them, as in the draw- ing. Formerly they were supposed to form a capsule of *' connective tissue," in which it was said the nerve cells were embedded. The ' cells ' are the sources of nerve force, which is, perhaps, closely allied to, but more probably identical with electricity. The currents starting from a cell traverse nerve fibres, which are often of great length, and, after being conducted along many fine fibres resulting from subdivision of the original nerve fibre, practically familiar with minute inquiry, by authorities who have been occupied in a totally distinct branch of scientific investigation, and who are quite ignorant of microscopical work. Microscopical observers have been told what they ought to have seen, and what they have seen has been condemned by ' philosophers ' whose remarks prove them to l>e absolutely ignorant even of the first principles of observation. E 5° MR. HERBERT SPENCER probably at length return to the same cell. Thus there are in every part of the nervous system exces- sively delicate fibres or cords forming continuous tracts. These constitute complete circuits, in various parts of which are situated the organs which are under the con- trol and government of the nerve centres, PL II, fig. 2. Nerve fibres are the cords which transmit the nerve force, and there has been much discussion con- cerning the character of the material which plays this very important part, and the changes which supervene when it is thrown into a state of activity. Attempts have been made to discover some peculiar structure or constitution of the active part of the nerve fibre, which will enable us to explain its action. Many very positive but very fanciful assertions have unfortunately had the effect of leading us away from the truth, and have encouraged the general acceptance of erroneous hypotheses in cases where a little con- sideration of the actual facts might have led to the adoption of a correct conclusion. It has been assumed that the active part of the nerve fibre (the axis cylinder) is composed of some peculiar colloid. Had Mr. Herbert Spencer examined the axis cylinders of some nerves, he would have found that the material of which they were com- posed very closely resembled some kinds of ordinary fibrous tissue. Of course it may be said, " that this resemblance does not prove identity, either of structure or composition." And it has been ON THE 'AXIS CYLINDER' OF NERVE. 51 argued, that wc must not draw conclusions from positive observations, because beyond the Hmit of observation there may be facts which, if they could be ascertained, might justify conclusions at variance with those deduced from the facts we have. But there is nothing to be demonstrated by investigation to justify the conclusion that the action of the axis cylinder is due to any special peculiarity of structure or com- position. The axis cylinder is composed of " protein substance," says Mr. Spencer, but this is not a pecu- liarity, since a number of tissues may be said with equal truth to consist of protein substance. It has been affirmed that the peculiar colloid "habitually changed from one of its isomeric states to another ;" but in this particular it would be difficult to prove that it differed from many other things. There is no more reason for supposing that the axis cylinder consists of '* matter isomerically transformed with case," than that white or yellow^ fibrous tissue consists of such material. Nor is there any reason whatever for assuming that a continuous length of fibrous tissue, or even moist thread, would not be an efficient medium for the transmission of nerve force, if it were protected and arranged like the axis cylinder of a nerve. It is very curious to notice the indignation of some philo- sophers if anyone speaks of vital power, while the)- themselves, in the most innocent manner, assume the discovery of peculiar colloids and matters isomerically transformed with case to suit the terms of any physi- E 2 52 FINE NERVE FIBRES. cal proposition which they feel disposed to propound. The attempt to show that a nerve is formed by physical changes, and acts by virtue of some peculiar chemical properties, has not succeeded. Of the Fine Nerve Fibres around an Artery. — The degree of contraction of the muscular fibres encircling every little branch of an artery, as represented in Fig. 2, is constantly varying, and this change is deter- mined by the varying intensity of the current tra- versing the nerves distributed to the muscular coat. Any alteration in the calibre of the artery instantly affects the flow of blood through the vessel, and a greater or less quantity of blood is distributed to the capillaries in a given time, according as the arterial coat is contracted or relaxed. In this way, through the intervention of a highly complex mechanism, the nerve centres exert an indirect but very important regulating influence upon the.process of nutrition. Distributed immediately external to the capillary vessels, are also very fine nerve fibres, branches of which join the network around the arteries. These nerve fibres of the capillaries are probably connected with the same nerve centres, and, perhaps, with the same cells as those from which the nerves distributed to the artery emanate. There results by this arrange- ment a very elaborate self-regulating mechanism of wonderful perfection, by which the supply of nutrient material to the tissues and organs of vertebrate animals is regulated according to the demand, and is PLATE III. NERVES TO ARTERIES AND CAPILLARIES, f'lg- ^- Fig; 2. Lt- 130 j^:'/ -A portion of a tanglion or nerve centre, situated at the side of a nerve, showing ganft- lion cells and nei-ve fibres aiound tbein, ■wbich ■uu into the trunk and are there distnbuted. r'rcm one of the nei^es of the pei-i< nulinin of the ox. X 130, p. 40 Portion of very small artery, showing mus- cular fibre cells and nerve fibres, ramifying in the areolar coat. Frog. X 700. p. 52. Fi^. 3. Capillary with diverticula from the roof ' fibres are seen very freely distributed . • Uaugeiu calibre without the nerves b'- rej. rve luy il^'o tooo of an inch X 7u(;. [To tac« pas? CAPILLARIES AND NERVE FLBRES. 53 altered according as the conditions to which the tissues themselves arc exposed as regards heat, mois- ture, and the like, undergo change. But into the consideration of this subject, interesting and im- portant though it undoubtedly is, as an illustration of the existence of arrangements which cannot be brought about by material changes alone, I must not further enter now. Capillaries and Nerve Fibres, Palate of the Frog. — In Fig. 3, pi. Ill, is represented a small capillary vessel from the mucous membrane of the palate of the frog. These capillaries exhibit at short intervals little pouches or diverticula, the use of which has not been fully explained, but which probably act as little reservoirs in which the blood remains partially stag- nant, so that the exudation of fluid from it for the nutrition of rapidly-growing epithelium is favoured. It must be obvious, from the position of the numerous nerve fibres seen around the capillaries, that very slight increase in the diameter of a vessel, consequent upon its distension by blood, would affect the nerve fibres ramifying upon its exterior. In consequence an influence would be produced upon the nerve centre which would be immediately followed by the convey- ance of an impulse along the nerves distributed to the artery (p. 52). Contraction of the little arteries distributing blood to the capillaries involved, would follow, and a reduced flow of blood through the capil- laries would be occasioned. 54 CAUDATE NERVE-CELLS. Vessels and Nerve Fibres of Miccoiis Membrane. — In Fig. I, pi. IV, is a representation of a very interesting specimen, from which the reader may gain an idea of the multitudes of bioplasts which exist in connection with some of the sensitive textures of man. The drawing represents a thin section of the mucous mem- brane of the human epiglottis of man immediately beneath the epithelium. Numerous bundles of deli- cate nerve fibres are seen ramifying in all directions, and interlacing freely with one another. Bioplasts are observed in connection with the nerve fibres. The majority of the nerves represented, probably take part in sensation, but a few of the finest fibres may be traced to the capillary vessels. Before the physical theory of life can be accepted, it must be shown how, according to that doctrine, the arrangement of the nerve fibres demonstrated in such a specimen may be accounted for. Large Candate Nerve Cells. — In the great central organs of the cerebro-spinal system of man, and the higher vertebrata, the elementary parts or cells are very large, and of an irregular form. These are the so-called caudate nei've vesicles, which should, I think, be regarded as stations where numerous nerve tracts cross and intersect, and then pass off from the " cell" in various directions, PI. IV, fig. 2. The bioplasm which takes part in the formation of these complex organs is situated near the central part of the cell. The so-called " nucleus," that is the PLATE IV. NERVES AND CAUDATE N£'^^"'' '''-''i.- Yip:. 1. i,i i^ Mucous membrane covering the epi^'.ottis, human subiect. T!i.» section )ia3 ho. n m.i beiieaih the epiLhelium. The capillaries with their masses ctlaoplaarn. are -vi;!! re iu Uie intervals are seen nximeroua bundl>^s of nerve fibres, witli tb'^lr biopla'^'ts. I , ''^ >re, however, far too delicate to be seen in a specimen magnitie'i only ulo diamev J^'lg. -.n." I'nr ruicl raii'lat-^ nerve cells from Ht" ruif ►■nfir li';,rii of tl,.' ,: • ■ "i in the formation • 1 some distance, di^- ' in ditTerent 'cells ' .i< nerves, humau sut;jcct x 13U. ; ■ of ill'? HT'iiial rrf'l. Tho . of ual CELLS OF TILE GRE V MA TTER. 55 inner part of the bioplasm or living matter of the cell, is not connected with the nerve fibres as some have supposed, but it is concerned in the formation of the soft material which constitutes the body of the cell, and which is traversed by the nerve currents as these course across the cell from one fibre to the others which leave it. Cells of the Gny Matter of the Convolutions of tJie Brain. — Caudate nerve-cells, smaller than those from the spinal cord, just referred to, but of the same type of structure, are found in other parts of the cerebro- spinal centres. In the grey matter of the brain they are very numerous. In fact the greater part of this structure is made up of these cells, and extremely delicate nerve fibres ramifying amongst them. Many of the cells are remarkable for tapering into one ex- cessively long fibre, which becomes very fine, and proceeds i\\ a direction towards the surface of the brain. This fibre passes some distance before it divides into its finest ramifications. Tlie fibres from the base of the cell, however, divide and subdivide into numerous branches as soon as they have left it. The arrangement is figured in 2 and 3, Plate V. If the reader will carefully examine Fig. 3, he will be able to form some conception of the vast multitudes of these cells in the grey matter of the brain of one of the lower animals (the Guinea pig). The piece represented is really not so large as the head of a very small pin, and is very thin,— much thinner than tlie tln'nnest 56 OF THE BRAIN. tissue paper. In a piece of grey matter of the size of a mustard -seed, there would be many thousands of such cells, and the space of one cubic inch would contain several millions. The relation and arrange- ment of the vessels are also well seen in the drawing under consideration. Occupying every portion of the intervals between the cells, are multitudes of fibres Avhich it is impossible to give in the drawing. A very imperfect idea of the arrangement may, however, be formed from the representation given in the lower part of Fig. i, pi. V, to the left. These fibres all come from cells, and each is in fact composed of numerous tracts along which nerve-currents pass. At each cell many different circuits intersect, and in this way lines are established between many distant parts and organs situated far from one another. These may all be influenced, and at the same moment of time, by changes occurring in one part of a single nerve circuit ; and complex movements of groups of muscles placed at ereat distances from one another and from their nervous centre, may be executed, and very different and distinct actions combined and harmonized most perfectly, and at the same instant. Is it right that authorities in other departments of knowledge, who arc perfectly ignorant of these marvel- lous arrangements, and lack the disposition to learn facts that others could teach them, having neither patience nor skill to examine the textures for them- selves and make out their structure, should assert PLATK V. CAUDATK NERVE CHILLS— (J RAY MATTER, yi?. 1. p-r Caudate nerve cells with, their flbrea from th« ^I'ny mntcer of the coavolutions of the brain, human subject. The bioplasm of the cells and that of the capillarv vessels is represented. The capillaiies are blue. X 350.. p. 56. Fitf. Angular caudace ucr'. , the gray milter of th-: lamb. The lon^ str i s directed upwards, pass towards the surfHC':; X 130. p 55. issues consUtuLiD^ the gray matter Brain of a Guinea pif%. The vess. : rusnian blue. a. part of a small artery with the bioplasm of th- loplasm of the nerve cells and vessels is ftvven. The nerve cella > u the part of the gray matter wlieuce this execimen was taken, ali p. 56. fonoth of an luch X 215. X 130. MR. HERBERT SPENCERS VIEWS. 57 most positively, and teach far and wide, that the whole of this marvellous mechanism was built by the sun and constructed by force ? But it is wonderful that the public should accept such assertions without question, and even delight in being told again and again that the brain is a force-constructed mind- evolving mill. The philosophers in question are, of course, unable to tell us how a single cell is formed, or how the wonderfully complex interlacement of fibres, which exists eveiywhere, is effected. They do not inquire how the fibre grows from the cell, and are uncertain whether, indeed, the processes of the cell are prolonged into nerve fibres or not. And numerous other structural matters of fundamental importance seem to be equally beneath their notice. They have decided to their own satisfaction what the nerve tissue is, or what it ought to be ; how it ought to act, and how it ought to have been formed, and according to them there is an end of the matter materially. I am sorry again to criticise Mr. Herbert Spencer's statement of facts, but the description given by him of the formation of nerve cells and fibres is in many respects so vague and incorrect, that it ought not to be allowed to pass. He says, '' the vesicles or corpuscles appear to take tJieir rise out of a nitrogenous protoplasm, ///// of granules* and * The granules, it is said, consist of "fatly matter," but how they came to be we are not told. 58 FORMATION OF NERVE CELLS, containing imcleir Now, every tissue in the body may be said to take its rise out of a nitrogenous protoplasm, so that such an assertion conveys abso- lutely no information respecting the formation of nerve cells. What the ^^ granules " maybe Mr. Spen- cer does not tell us, nor does he consider it necessary to account for the origin of the nitrogenous proto- plasm, or to describe the nature and properties of this particular nerve-corpuscle-forming matter. Round these nuclei, he goes on to remark, "the protoplasm aggregates into spheroidal masses, which, becoming severally inclosed in delicate membranes (in many cases inferred rather than seen) are so made into nerve cells ! " Now, this statement is altogether unsup- ported by observation ; it is, indeed, positively in- correct. The protoplasm does not aggregate at all, the masses are not severally enclosed in delicate membrane, and nerve cells are not made in the nianner described. Further on, it is affirmed that the *' nucleated cells, or nerve-corpuscles, give off processes ;" but how they '* give off " processes, or what makes them give off processes, we are not told. But the processes are not formed by being ''given off" from the cells in any case, as far as is known. The cells which were originally connected move away from one another, and the process or in- tervening fibre is as it were drawn off from them. It is evident from his description, that Mr. Herbert Spencer has but a very imperfect notion of the struc- ACCORDING TO MR. HERBERT SPENCER. 59 tures he describes, and has not seen them. If he has examined specimens, they must have been very im- perfect, or the method of conducting the examination faulty. In explaining nerve action, Mr. Herbert Spencer seems to consider that the active part of the nerve fibre is protoplasm, and the material out of wliich the nerve fibre is formed is, according to him, also proto- plasm ; but these two kinds of " protoplasm " are as distinct from one another as the moving, living, growing protoplasm of the white blood corpuscle is from the stationary, firm, solid, passive white or yellow fibrous tissue. Things so very different, should be de- scribed differently, and cannot be supposed to act alike. The tissue, moreover, never "builds up." It is the particles of the matter, while in the living state which " build up," and arrange themselves, or are arranged by some force or power active in this temporary exceptional (living) condition. The assertion that "among the corpuscles and their branches are dis- tributed the tcnninations of nerve fibres " is another error, for no terminations whatever have been demon- strated by anyone in any nerve-centre. Neither is it true that in any nervous centre " the connections between fibres and cells are rarely, if e\cr, direct." I have introduced these criticisms to show that man}' of the so-called facts upon which certain conjectural views have been based are only facts of the imagina- tion of privileged persons. 6o OF THE BIOPLASM TAKING PART But I will not pursue this subject more in detail in this place, as my object in referring to the structure of tissues is only to direct attention to the living matter, which has been completely ignored by many physical philosophers, but is nevertheless to be de- monstrated in connection with all the tissues of man and animals, and from which everything in their bodies has been formed. ■ Before leaving this part of my subject, however, I must say a few words upon the elementary parts of the brain, which are, I believe, the bioplasts imme- diately concerned in the active operations of the mind These are situated in the soft grey matter which forms the convolutions of brain, consisting of an enormously extended thin layer, so folded as to occupy the least possible space. Bioplasm concenied in Mental Nerve Action.^ — Near the surface of the grey matter in that extensive layer above the planes in which the caudate nerve-cells are situated, which is generally said to be composed of delicate nerve fibres and "granular matter," I have succeeded in demonstrating multitudes of very small masses of bioplasm lying amongst the finest branches of the nerve fibres, something like those which consti- tute the so-called "granular layer" of the retina and of the cerebellum. In some places there are aggre- gations or collections of these bodies. They are * The following description is taken from "Protoplasm," but the plate illustrating these remarks is new. IN MENTA L NER VE AC TION. 6 1 nearly spherical, are extremely delicate, and become disintegrated very soon after death. Some sections of grey matter appear to consist almost entirely of these bodies, so great is their number. Some seem to be connected together by very delicate processes of the same transparent material. Masses of bioplasm thus situated are arranged very favourably for influencing the fine nerv^c fibres which ramify amongst them. Figs, i and 2, pi. VI, p. 62. It is obvious that the slightest change in their form could not fail to affect the nerve currents traversing these fibres, and as we are now well acquainted with the active movements of bioplasm, it is impossible to help suggesting that the movements occurring in these masses of living matter produce a direct effect upon the adjacent fibres. These vital movements or vibrations occurring in matter of excessive tenuity constitute, or are the immediate consequences of mental vital action. The directions in which the living matter is made to move by the conscious life-power which directs it, will determine the par- ticular cords of the nerve mechanism to be struck ; the special movements may be the expressions of the inward ideas. If this be so, mind is the vital power which is associated with this the most exalted form of living or germinal matter, so arranged that the slightest change occurring in it may produce indirectly an effect through the influence of a most elaborate mechanism, brought into very intimate relation with 62 CHARACTERS OF BIOPLASM. it. Does any one, who has studied structure, really believe that through physics or chemistry the slightest approach to an explanation of the formation of the mechanism or of its action will ever be made ? The conclusion that will be drawn from the facts ascertained by a careful examination of the several preparations just described (and almost any others prepared like these would have equally answered my purpose), is that the physical doctrine of life appears plausible only if the facts of nature are regarded very cursorily and superficially. As we investigate more minutely we find that difficulties present themselves to this physical interpretation of the facts, and these difficulties increase in number at every step. If we employ the highest powers, and so prepare the tissues that the delicate structure is very slightly deranged, we see great reason to demur to the acceptance of the physical doctrine of life. While, if we investigate the distribution of the bioplasm, study its arrange- ment and relation to the different tissues at different periods of life, and submit living bioplasm under favourable circumstances to the magnifying power of from 1,500 to 3,000 diameters, the conviction will force itself upon the mind that any attempt to explain by physics the phenomena we demonstrate must utterly fail at this time. PLATE VI. BIOPLASM 01'' GRAY MATTER— PROBABLY CONCERNED IN THOUGHT. Fig. 1. 6 I5J0HES REMOVKlP. b KE&R PIA MATER. Vertical section through superficial part of gray matter of cerebral convolutions, human sub.iect. In part schematic, o. caudsite nerve cella with long processes directed to—nHs tho snrfnc; "f the gray matter to the left of the page. Tissue occupying an extent of six ii ' -'1 from the diawiui^ under letter 6. c. nerve bioplasts, suppcseil to take [ "• Numerous excessively fine nerve fibres prolonged fiom tht- cells and libres ' . u of the gray matter are seen in the intervals between the bioplasts. Reduced ii-.au tiji lo _;5. o, i.. oi. Fis-. 2. C- ^., -^ artery is seen on the lett. ibis, and ii superficial part of the gray matter are r- ly in the u ijVici oi an inch VITAL PHENOMENA AND VITALITY. We may now consider some of the vital pJicnoinena which are common to every form of bioplasm in nature, from the lowest and simplest to the very highest. Characters of the Bioplasm. — The living" matter has been proved by the aid of higher magnifying powers than had been used before 1863, to be clear, trans- parent, and structureless. I have shown tliat the phe- nomena of growth, nutrition, and multiplication could not be explained by any structural or mechanical arrangements. No structure of any kind can be seen, even when the bioplasm is magnified 5,CX)0 diameters.* The remarkable fact was demonstrated that a minute portion of transparent, colourless, living matter exhibited very peculiar movements — move- ments which could not be explained by any known laws. One part of the bioplasm could be seen to move in advance of another part, or over it, as it were, or through it, just as if the mass of living matter consisted of colourless fluid, every particle of which had the capacity of movement, and at the same time. One part could be seen to move, as it were, into or through another part, in one case blending partially or completely, in another apparently remaining dis- tinct from the rest. * "On the Structure and Growth of the Tissues," a course of lectures delivered at the Royal College of Physicians, April and May, 186 1. 64 GROWTH, NUTRITION AND ACTION. The bioplasm embedded in a tissue (pages 44, 45) does not pass gradually into the formed matter, as some have asserted, but the transition is sudden and abrupt. The living appears to be in contact with that which has ceased to live. In a given bulk of the matter of the different tissues of the living body and at different ages, the relative proportion of the living to the lifeless matter varies greatly (Plate I) ; but every little particle of bioplasm has upon its surface, in contact with it, lifeless matter, which may be very sparing in quantity, as in quickly growing tissues, or constitute by far the largest part of the matter. This living matter is intimately concerned in the growth, mUrition, and action of every texture of every living being, animal, or vegetable, as long as It re- mains alive. Towards every one of the minute masses of bioplasm represented in the Plates In this volume, currents of fluid, holding nutrient matters In solution, flowed during life. In this way every portion of the surrounding tissue, it will be observed, must have been continually bathed with fresh fluid, and thus it was preserved in a state favourable for the discharge of its function. Nor is it possible to ex- plain any of these processes without taking into account the phenomena of the living matter. If the living matter dies, these processes at once stop. A particle of matter cannot, I think, be either half alive or half dead. It must be living, or It must absolutely have ceased to live. When we study a thing that is OF LIVING MA TTER. 6 5 alive, we do not find that every particle of the matter of the being lives, but that only the bioplasm of its organism is actually living. This only can grow and take up nourishment and convert and multiply. And if we study the ordinary phenomena of living beings, we shall find that they may be traced to their antecedent phenomena, through per- haps a long chain, until at last we arriv^c at the really vital phenomena of the bioplasm or living mat- ter. But at this point our investigation for the present must stop. For let us suppose that a most skilful chemist sets to work to ascertain what this living matter is made of. Ere his chemical analysis can commence the matter has passed from the living state, and ail that he can do is to ascertain the nature of the chemical substances which are formed when it dies and after its death. The chemical com- position of living matter is unknown and probably unknowable, for it is impossible to analyse matter that is living. To assert therefore that living matter is "protein" or "albumen" is to assert that which never has been and never can be proved, and all arguments based upon such assertions must be discarded. To say that living matter consists of these things changed or modified is mere evasion, and any physiologist who adopts this expedient evades the consideration of the question, for of the chemistry of the living matter itself, and of the manner in which the chemical changes arc eftectcd,he is aware that he knows nothing. 66 VITAL AC TIONS and that nothing is really known. No one has been able to give any explanation of the phenomena re- garded from the physical point of view. We can all of us see living matter move, see one part raising itself above and in advance of another part, in spite of the action of gravitation ; but the most delicate refine- ments of physical research have so far failed to help us to discover the nature or cause of the movement, or even to afford any conception of the exact changes which occur while the movements are going on under our eyes. The assertion that the movement is moleculaf and a consequence of previous molecular changes is mere pretence of knowledge, for, as before stated, nothing whatever is known of the molecular phenomena supposed, or of the changes which give rise to these. So far therefore it is right to regard the distinction between the living and the non-living as absolute, and all hypotheses which are based upon the idea that this difference is one of degree only and that vital power is but a mode of ordinary force must be abandoned, although no doubt physical views of life will yet be urged upon the attention of unlearned people. Observers who are acquainted with the facts and arc able to investigate details will condemn them because they are opposed to reason and calculated only to mislead the ignorant. Those who seek to explain vital actions by attri- buting them to antecedent changes, are in a somewhat better position than those who assert the changes to NOT EXPLAINED BY P/IYS/CS. 67 be actually molecular, although this view is also un- tenable. The doctrine under consideration rests upon the idea of the dependence of every change upon an antecedent change. But who can tell us anything concerning the nature of the change antecedent to the changes Avhich can be observed in living matter } As yet we have no means of following up the inquiry one step beyond the observed change. It comes then to this : that the physical doctrine at this time rests upon the assertion that the phenomena of living matter are of the same order and nature as the phe- nomena of non-living matter. There are absolutely no facts to which the advocates of this doctrine can appeal in support of their conclusion. Analytical operations do not enable us to learn anything con- cerning the changes of the actual bioplasm or living matter. Neither physicists, chemists, nor any other scientific investigators can explain to us the nature of the changes which occur in it. We know of the phenomena, but to account for them by any laws of nature now known is not possible, and it is surely presumptuous, instead of being philosophical, on the part of any one to permit himself to assert dogmati- cally that the changes must he p/iysieal ixnd due to the operation of the same laws which affect non-living matter, because all change is physical and all laws are physical laws. Nutrition. — Living matter, if placed under certain conditions as regards temperature, moisture, and light, F 2 68 TISSUE IS NOT NOURISHED. and at the same time surrounded by fluid holding in solution certain compounds, increases in amount. The matter which is added and which becomes part of the mass cannot after its incorporation be dis- tinguished from the rest. In other words, the living matter takes up non-living matter and converts this into living matter. This is nutrition. It is generally supposed that this process of nutri- tion goes on in every particle of tissue, — that, for ex- ample, the fibrous tissue sckxts from the blood con- stituents which become fibrous tissue, — that in the same way muscle and nerve and other textures select the proper materials adapted for their increase. But this is not so. The tissues have no such selecting or metabolic properties. The bioplasm only possesses the marvellous power of taking into itself certain mat- ters, and of changing them in such a manner, and at length of undergoing conversion into tissue. Without bioplasm there can be neither nutiition, nor growth, nor development, nor tissue-formation of any kind. But further, when a mass of living matter is freely supplied with pabulum instead of increasing indefi- nitely, it attains a certain size and then undergoes division. In this way the number of masses of bio- plasm increase during the period of development and early life. In many parts of the body this increase continues while life lasts, but the growth and multi- plication of different forms of bioplasm of the body, and of the same form at different ages take place at BIOPLASM IN DISEASE. 69 a very different rate. These, like other phenomena of the bioplasm, are inexpHcablc by physics, and all conclusions concerning the nature of growth, nutri- tion, and increase which rest upon the assumption that these phenomena are plu'sical and chemical arc unsound, illogical, and misleading. Such \'iews re- tard progress and tend to prevent the spread of natural knowledge. Bioplasm in Disease. — The bioplasm or living matter circulating in the fluids and embedded in the textures of the body undergoes most important changes in disease. Oftentimes it increases to many times the volume it occupied in the healthy state, and thus the most terrible derangement of many physiological pro- cesses may be occasioned, and in several ways. In every form of fever and inflammation the bioplasm increases, and its increase is associated with the development of heat. Living matter or bioplasm constitutes those minute particles known as disease genus, which are the agents concerned in propagating all contagious diseases.* Having escaped from the infected organism, the particles of contagious bioplasm, often less than the Too'ooTT of an inch in diameter, may be wafted by currents of air, perhaps through very considerable distances. If any of them accidentally come in con- tact with an organism in a state favourable to their growth and multiplication, they may pass into tlie blood, grow and multiply, and establish a state of * See "Disease Germs, their Real Nature.'' January, 1871. 70 PRODUCTIOX OF FORMED MATERIAL. disease like that existing in the organism whence they were derived. It need scarcely be observed that the changes of bioplasm in disease are not to be explained by mechanics or chemistry. Pi'oduction of Formed Material from Bioplasm. — Not less wonderful than the other vital phenomena to which I have adverted is the following, which occurs whenever tissue of any kind is formed. A mass of living matter undergoes change upon its surface. Some of the living material loses its vital powers, it ceases to be nourished, and ceases to grow. Part of the living bioplasm in fact ceases to live. It dies and is changed. The elements of which it con- sists are rearranged, and thus lifeless formed material and non-living tissues of every kind result. Many of those most beautiful and transparent jelly- like creatures known as animalcules, which exhibit such wonderful activity in warm weather, become torpid and perfectly quiescent when exposed to cold. If they be examined in winter, it will be found that the beautiful transparent textures have become granular, and highly refracting insoluble particles can sometimes be detected in considerable number. These changes result from the death of part of the living matter of which these delicate organisms were in great part composed. By the accumulation of dead matter (cell-wall) upon the surface of the bio- plasm, what remains of this is protected and saved from death. When spring returns and external con- BIOI'LASM AND FORMED MA TTER. 7 1 ditions become favourable to growth, many of tlie lifeless granules are cast away, and the living matter escapes from the dead capsules, or much of the dead matter may be taken up by the little bioplasm which remained in a living state. This then rapidly in- creases, and a mass of living matter having the characteristic transparency and delicacy of appearance soon results. Changes of the same kind occur in bioplasts of all living things under certain alterations of the conditions under which they grow and live. Bioplasm and Formed Matter. — The passive formed material around the bioplasm has resulted from changes in the bioplasm itself. For^ned material cannot form. Formed material is as different from the living matter as the wood of the table from the living growing tree. Some advocates of the physical theory of life call these two different kinds of matter by the very same name, and in this way they seek to make people believe that there is no real absolute difference be- tween the two — between that which lives and that which has lived. Matter in these two very different forms or states has been called by the same name, protoplasm. Ikit even Mr. liuxley is obliged to acknowledge that there is a difference, although he has succeeded in hiding it for a time by the ingenious device of telling people that the protoplasm is ^^ variously modified ! '' And he informs his readers by what forces the modification is effected. He says the matter is modified by '* subtle influences." 7^ LIVING AND NON-LIVING. According to the present philosophy, the living is but modified lifeless. The watch then is but the modified brass or steel. Grass is but modified earth, man only modified dust. And the conversion of the lifeless into the living, of the metals into the watch, of the earth into the grass, and of the dust into man, is effected not by any immaterial agents whatever — not by such fictions as vitality, but by tangible demon- strable, accurately defined means which physical philosophers can render evident to the senses of privileged persons, and which pass by the names of " conditions," '* circumstances," and *' subtle in- fluences." At no previous period in the history of science have such poor attempts to palm off as an explanation that which is but an assertion, been so successful. Ne^ver before have people been led to accept as explanations such phrases as " variously modified." Anyone accustomed to analyse the meaning of terms though he possessed no scientific information whatever, could, with very little trouble, resolve such explanations into mere wind and words, but unfortunately in these days people will not take trouble, and are too busy to study, to analyse, to weigh, to reflect, — and more respect is excited by the dress in which observations and argu- ments are clothed, than by the observations and arguments themselves. Objections to the Idea of a Central Force or Pozuer influe7icing the zuhole Organism. — Some have enter- A'O CENTRAL COVER XING FORCE. n tained the idea that the phenomena of the organism of man and the higher animals, can only be accounted for by admitting the action for some central guiding, directing power, capable of influencing all the organs and tissues of the body in somewhat the same way as the master builder controls and directs the opera- tions of his workmen. To such hypothetical influences have been attributed many complex phenomena not easily accounted for. But there is no good reason for believing that any such central mysterious presiding unity, force, property, or agency exists in some one part of the body, and from the first dawn of life influences regulates or controls the numerous and highly complex phenomena simultaneously occurring in every part of the living being. Regularity of growth, Development of structure, Maintenance of nutrition, and Harmony of action, can be other- wise accounted for. It is therefore unnecessary to resort to an h\'pothesis which invoh-cs the untenable doctrine that lifeless tissue in the body is influenced by some apocryphal central force which commands it, which efl*ects changes, governs by some undiscovered laws, and operates in some at present inconceivable manner and in many difl"erent directions through difl"erent kinds of matter, and at very varying distances at the same in.stant. There is no better rea.son for assuming 'Mife" to be located in one central spot, than for the old view that it was established in the blood, and was distributed elsewhere by this fluid. 74 LIFE OF THE BIOPLASM. The evidence I have advanced is, I think, conclu- sive in showing that the only life in the body is associated with bioplasm, some of which is to be found in every tissue and organ in every part of the body and in the blood at every period of life. The only particles capable of being influenced by vitality are those which are actually living ; in fact, the matter of which the bioplasm itself consists. But the different forms of bioplasm which are con- cerned in the formation of different tissues and organs of the body, possess special vital powers. The mar- vellous manifestation of vital power by which man is so widely separated from all other beings, does not emanate from the bioplasm of the tissues generally, but is limited to that of one special tissue. Neither the bioplasm of bone nor that of muscle nor skin, nor that which takes part in the formation of glands, is the seat of those phenomena which absolutely sepa- rate man from every other being in nature. There is no reason to suppose that man's bone and muscle, skin or glands, are in any essential points very different from the corresponding structures in the lower animals. But the particular kind of bioplasm which takes part in intellectual action resides in the brain of man alone. Between this and every other form of bioplasm in man's body and elsewhere, there is a transcendant difference, not, however, in the matter of which it is composed, but as regards the power with which it is endowed. Q UESTION OF NEK VE I NFL UENCE. 7 5 The bioplasm of all the different tissues of the body has been derived by descent from one mass of bio- plasm. After the bioplasts have once been detached, they do not probably exert any direct influence upon one another. That bioplasts with certain special en- dowments or properties, eventually result by division from the original bioplasm is certain, but neither this fact nor the sort of power manifested, could have been premised, however carefully the original mass of bio- plasm had been examined. No knowledge of the properties, characters, or composition of the matter would have enabled us to form any conception of the nature of the actions it was to perform. It has been supposed by some that a central force operates on the distant parts of the body through the nervous system, but it is certain that neither the arrangement of the tissues to form organs having special functions, nor their actions, can be accounted for by any governing or directing agency brought to bear through the intervention of nerve. Indeed, this tissue is not developed at the time the arrangements in question are determined and carried into ettect. The nervous system, instead of being developed first, as it undoubtedly would be if it was to exercise the function supposed, arrives at maturity the very last of all the tissues. The highest form of bioplasm de- veloped, and the only one which could be supposed with any show of reason to exercise sway over all the rest, and over the various tissues formed, is the y6 ^'0 CENTRAL POWER very last to appear in the order of development, and is not in action until long after many of the changes supposed to be due to some central force or pov/er have been com.pleted. To this, the last produced, every other form of bio- plasm appears to be in a manner subordinate. Other forms seem to have been called into being in order that this might exist. The tissues and organs, ministering to the well-being of this highest form, are perhaps not necessary to its actual existence, but are required for preserving it in a state of integrity, while some are employed as the instruments through which alone such a power can express itself, and be brought into relation with, or produce any effect upon the non-living matter around it. There is then no reason for adopting the conclusion that the several tissues and organs which constitute an organism are under the influence of any central power capable of exerting any general control upon all ; but after a careful examination of the facts ascer- tained during the course of development and forma- tion of a tissue, the inference is deduced that each tissue is formed by living matter, which exerts no direct action or controlling influence upon the living matter of other and difl'erent tissues. Nor do the particles of living matter of the same tissue exert any direct influence upon one another. A long series of changes occurring in regular pre-ordained order, results at last in the complete development of a COXTROLLING ALL THE CHANGES. 77 texture. If, after development is completed, the various conditions which have themselves in great part resulted from the occurrence of previous de- velopmental (vital) changes, are not disturbed, the growth and action of the tissues is preserved. But derangement of any one organ may interfere with the proper action of others, either by influencing the composition of the nutrient matter distributed to all, or by disturbing the action of the nerves which supply them. Vital PJicnomena and Physical PJicnomena of a Dijfcrent Order. — But it has been shown that the phenomena of living matter are quite peculiar, and are limited to the living matter which has been de- tached from a mass of matter that was alive. A wide distinction, therefore, ought to be drawn between the vital pJicnomcna occurring in living matter and the physical and chemical phenomena of the non-living matter of living beings. The living is altogether different from the non-living, and the former in no way involves the existence of the latter (page lo). In all living beings there are indeed two distinct sets of phenomena, vital and physico-chemical. The vital phenomena exhibit no analogy whatever to the ph}'sico-chemical phenomena. The physical proper- ties of the molecules are no more capable of being lost than the molecules themselves, but the vital properties may disappear and never again be mani- fested by the same particular molecules. 7 8 VITALITY. It must, however, be acknowledged that we are not able to adduce scientific evidence in proof that the living can exist independently of the non-living, be- cause the only evidence obtainable by us is obtained from and through the material. Such a conception, however, may present itself to the mind, and it seems not unreasonable to believe that vitality may after all belong to an order of activities or immaterial agefits of which we can really learn nothing directly by the assistance of our senses. Nevertheless, from the effects of the supposed agency upon matter, we can conceive of it as an actual existing power, and by studying accurately the results of its working, why should we not succeed in drawing a correct conclusion concerning its nature and the mode of its action upon matter } Vitality. — The vital power transcends altogether physical forces, for it controls, guides, directs, ar- ranges, while the latter are controlled, are guided, are directed, 8zc. Power may be said to guide and govern force. Power is one thing and force another. Some such view as that which I have endeavoured to sketch concerning the nature of life will, I believe, be found to constitute the only possible basis of re- ligious thought regarded from the scientific and philosophical side. Starting from a theory of vitality we may, I apprehend, surely and almost infinitely extend natural religious thought. We may find after all the conflicting arguments shall have been 17T,ll./TY. 79 thorougly considered, that reason and faith excite and justify the same hopes and aspirations. Vitality, it must be remarked, unHke any physical agency yet discovered, manifests a remarkable capacity, so to say, of prevision. The changes effected by livins: matter at one time are carried out as it were in anticipation of future change, as if the conception of what ivas to be had been acted upon even while the early changes were proceeding. Now this preparation for future change is to be noticed from one end of the living world to the other, and with marvellous dis- tinctness as regards the operations of the intellect. For it is unquestionable that in the case of the organ of the mind of man, change paves the way for further change, and each advance renders possible a further onward development, the possibility of which was as it were anticipated almost from the first, though this could never have taken place had not certain pre- paratory changes, as it were, cleared the way for others which were to result in the formation of the perfect structure. By the increase or diminution in the number of the bioplasts, the uniformity of the nutritive process as it occurs in all tissues and organs, is preserved. Excess of nutrition is stored up by the increase of bioplasm in times of scarcity. Vitality cannot be converted into mechanical energy, or other mode of ordinar)^ force, nor can any modes of force be converted into vitality. Vital So OPPONENTS OF VITALITY. power is transmitted from living matter to non- living matter witJioiit loss, and in a manner perfectly peculiar, to which there is nothing analogous in the non-living world. The particular theory of vitality I have proposed, has met with little favour at the hands of those who have committed themselves to the modern phase of retrograde Epicurean philosophy ; but the principles on which this doctrine of vitality rests, have not been disturbed. The position, indeed, is daily gaining real strength. Not a few opponents very powerful, and armed with weapons they well knew how to wield, have retired from the assault, after having very loudly boasted of what they were about to do. Some have preached and some have prophesied, while others have affirmed, that mighty changes are about to occur, and that extraordinary revolutions in thought were being effected under their auspices. Some have made the strongest assertions concerning the facts and laws they say they know, and have exactly defined the precise direction in which the thought of the day is tending, and indicated the line which is to guide its tendency in the time that is to come. An expositor of the physical theory of life has triumphantly de- clared that many things may be going on beyond the limits of the knowable, and has drawn attention to the intense love of truth manifested by the sup- porters of the physical doctrine of life, and their hatred of that which, according to the physical dictum, OPPOXEXTS OF VITALITY. is not true. Opponents of the vital theory have in- dulged in exclamations about their own beliefs and individual convictions, and in eloquent rhapsodies about what might be seen if it were possible to see under circumstances which unfortunately not only pre- clude vision, but render existence impossible. After abandoning the safe ground of observation and ex- periment upon which they used to take their stand, ardent supporters of the physical view appeal to the discoveries of the imagination, to conjecture, and fancy, while their teachings, gradually losing all potentiality, will, it is probable, ere long pass into a latent state, and eventually resume the form of primeval mist and fiery cloud. For some time past retrograde and long-discarded ancient fancies have been revived and advanced in support of doctrines as hopeless as the materialism of Lucretius. Conjectures recently distilled from the laboratory of the imagination have been forced upon public attention, and though almost identical with some views exploded centuries ago, being habilitated in modern garb escape recognition, and api)ear to many as new discoveries. Those who do not receive them are called " narrow,^' " prejudiced," "orthodox," and no wonder that in these days when the con- sequences of such epithets, especially when hurled with the force pure ph}-sicists can alone give, are so disastrous to individuals, the advocates of the truly G 82 NATURE OF LIFE. broad physical dogmas should be very numerous and powerful* After having studied the phenomena of living matter for a length of time, and with all the ad- vantages I could obtain, the conviction has been forced upon my mind that vital phenomena must be referred to the influence of an agency distinct from the physical forces of nature. The hypothesis I have been led to adopt is this. I suppose that there is operating upon every particle of every kind of living matter a forming, giiidingy directing power or agency which is constantly at work, being trans- mitted from atom to atom. This overcomes, and in a moment, all the ordinary attractions, affinities, and other properties of material molecules and in a man- ner with which there is nothing comparable in the non-living world. The difference between the lowest simplest germ of living matter and the highest is * Nevertheless, the amazuig confidence displayed by the disciples of the new philosophy, when teaching their views to the unlearned, is very remarkable. All science is now physics. Nothing that cannot be com- prised under the term physical is either scientific or worthy of any thought or consideration. As for the teachings of religion, history, art, and what used to be called philosophy, they are not only absurd but unworthy of refutation. All that these deserve is to be simply ignored, as if they were not and never had been. The physical view, it is arro- gantly asserted, is the "scientific view," the physical tendency of thought is the scientific tendency, and so on. All other views and tendencies are not scientific, but frivolous and ridiculous, and only to be •tolerated for a time by physicists, out of respect for the too slowly waning prejudices due to defective education and the weakness of the public intellect. LIVING MA TTER. 83 not to be accounted for by any difference in compo- sition, but only 'by supposing a difference in power, which power has been derived and transmitted on- wards, as it were, and without loss, from matter having the same power. Life is not a consequence of the organization of matter, but the cause. Life precedes, instead of suc- ceeding organization, conversion, formation. The first impulse is exerted from within the living matter upon the lifeless matter which is brought under the control of vital power. The tendency is from within and is not excited by actions going on around. Living matter always tends to grow, move, &c., and when the restric- tions under which it is placed are removed, the vital phenomena are manifested with such increased acti- vity as to be readily observable. In the present day writers on the physical side are never tired of urging us to believe that all those marvellous phenomena peculiar to the living world are not peculiar to it at all. Even Mr. Herbert Spencer does not hesitate to assert that "■ organisms are Jiiglily differentiated por- tions of the matter forming the earth's crust and its gaseous envelope." Then he goes on to say, " The chasm between the inorganic and the organic is being filled up.'' But if this sort of statement is accepted as proof philosophical we may surely prove anything wc like and then assert that it has been proved philoso- phically. He says further that there are organisms the matter of whose bodies is " distinguishable from a G 2 84 PHYSIOLOGY NOT AN fragment of albumen only by its finely granular cJia- racterl' * The reader will observe that no facts what- ever are adduced in support of these most cleverly stated assertions. They do not result from observa- tion or experiment, but rest upon authority only. The " highly differentiated " is not more definite than Mr. Huxley's "variously modified." Neither does the author tell us by what the chasm between the organic and inorganic is being filled up. But he is wise in using the words organic and inorganic instead of living and non-living ; for if these last were substi- tuted for the former the assertion would not be ac- cepted by anyone. But are not the "distinguishable," the " fragment of albumen," and the " finely granular," as employed in the above sentence, remarkable for that vagueness and ambiguity which characterise the recent developments of material speculations } Physiology has been positively affirmed by Herbert Spencer to be " an interpretation of the physical pro- cesses that go on in organisms, in terms known to physical science," but, seeing how very little physio- logy can be explained by physical science, and that of the essential changes which distinguish all living from all lifeless things, not one can be explained without " a psychical factor — a factor which no phy- sical research Avhatever can disclose, or identify, or get the remotest glimpse of," — it is clear that such an interpretation of the "physical processes" as that * Herbert Spencer, p. 137, vol. i. Second edition. INTERPRETATION OE TI/YSICAL TROCESSES. 85 indicated will teach us nothing whatever concerning the physiological changes which distinguish all living matter from all non-living matter. No interpretation of physical processes helps us in the least degree to explain the phenomena which occur in the smallest particle of the simplest form of living viattcr which are due to some agency which acts in a direction from centre to circumference. No physical explanation, it need scarcely be remarked, will account for portions of a mass of semi-fluid matter moving away from one another, and in many different directions. In short, no physical explana- tion will enable us to account for the phenomena of growtJi, nutrition, multiplication, formation, conversiofiy or other vital phenomenon. Do not the words " physiology," " biology," "pathology," "health," and "disease," impl)- pro- cesses that are not simply physical, — imply in fact a psychical factor.^ In spite of all that has been urged to the contrary, there is not one of the actions pro- perly called physiological, biological, pathological, healthy, or diseased, that can be regarded as wholly physical, mechanical, or chemical in its nature. Not only so, but the very terms employed by the physicists themselves in describing phenomena occur- ring in li\ing beings, and stated by them to be physical, actually imply properties or forces which arc not phy- sical. The possession of advantages by certain fortu- nate creatures in the struggle for existence, is often 2,^ NON-PHYSICAL FACTORS. spoken of as if it depended upon material changes only, but the capability for enjoying or profiting by advan- tages implies something other than physical forces and properties. Living things have been said to resemble crystals in growth and in some other points. But fancy a crystal or other inanimate object enjoying advantages, or strugglijig for existence, or the various forms of carbon or calcareous spar being produced by " natural selection ! " It will be found by any one who takes the trouble to institute the examination, that those who maintain the physical doctrine of life imply by the very language they use the occurrence of non- physical changes which they deny, while they are constantly, but apparently unconsciously, calling in the aid of non-physical factors, " subtle influences," " tendencies," " capacities," " plasticity," and the like, to account for phenomena which they pertinaciously insist are physical. It comes indeed to this, that unless we ignore the facts of observation, or decline to make any attempts whatever to account for the phenomena of living beings, we must abandon physical, explanations which have ever proved incompetent, and resort to hypo- theses of another kind. We are really obliged to assume in the case of any form of living matter the existence of a power acting in a direction from within outwards, and the facts necessitate the conclusion that new vital power originates within the very centre of a minute particle of the matter which is alive,— BIOPLASM COXCERXF.D IN MIXD. 87 which is ill the peculiar vital state. Tliere is no action known to occur in non-livini^ matter of any kind which can in any way be compared with this. Of the nature of this vital power I can only form some dim conception from the results of its action, but when the necessity for the hypothesis of vital power shall have been admitted, it is likely that rapid advance will follow in our views concerning the influence exerted by certain non-physical influences and agencies in things li\'ing, which are now^ entirely ignored by physicists. Thoughtful persons have long felt extremely dis- satisfied with the material doctrines of life now so prevalent, and though doubtful concerning the precise terms in which the influence of some non-physical power ought to be stated, have acknowledged that the facts rendered imperative the admission of an agency belonging to an order very different from that in which physical and chemical actions are comprised. Such agencies will be advantageously considered now that the depressing influence of the physical force tyranny is happily once more ceasing to retard progress and oppress thought. Of the Action of the Bioplasvi concerned in Mental Action. — The action of this the highest form which bioplasm is known to assume, has been carelessly attributed to physical and chemical cliangc. But there is not a shadow of fact to justify the dogma that mind is a form of force. The little bioplasts 88 VITAL ACTIONS. described in page 6i, and which are probably directly concerned in every kind of intellectual action, are exactly like the bioplasts which exist in every part of the brain, and indeed elsewhere, at an early period of development. They consist almost entirely of living" matter, and retain the general characters they exhibited from the first, while life lasts. They vary in number at different periods of life, and increase under certain conditions, like other forms of bioplasm. They are unquestionably more numerous in some spots of the grey matter than in others. Even in the aged these bodies, representing the highest form living matter is yet known to assume, still retain the cha- racters presented by every form of bioplasm at an early period of development. Their exalted function and wonderful powers could not possibly be predicated from a knowledge of their microscopical characters or chemical composition, or from a knowledge of the properties of the elementary substances into which they may be resolved ; but in this respect they agree with every known form of living matter. These wonderfully endowed masses of bioplasm would be called granular particles, and ^\ould be classed with other bodies possessing similar characters and of little significance. We should anti- cipate that of all kinds of bioplasm known, that con- cerned in mental nervous action would be most evanescent, and prone to rapid change and disintegra- tion after death. It is therefore not surprising that AV STKL'C'/rRE IiV LIVLYC MATTER. 89 ill many cases no traces of the delicate bioplasts I have described should be discoxcred. I feel sure that what I have been able to demonstrate affords but a YQxy imperfect idea of the very <^reat number and perfect order of the masses, as they exist in the living state. Considering^ the nature of this form of bio- plasm, we should anticipate that chany^e would almost immediately follow the death of the indi\ idual, and that these delicate bioplasts would be completely broken down long before other kinds existing in the same organism had ceased to manifest their \ital pheno- mena. Observation convinces us that the activities mani- fested by different forms of living matter are depen- dent, not upon peculiarities of structure or composition, (for these exalted bioplasts look like many forms of mucus and pus corpuscles, and move like small amcebcTe and the simplest forms of living matter known), but upon something quite distinct from these, and of a different order altogether. The matter which mani- fests vital actions possesses no structure, and it is impossible to ascertain its chemical composition, and the objection that structure migJit be discovered, and chemical composition determined if our means of investigation were more perfect than they are, cannot be sustained, and ought never to have been advanced ; for, first, the structure of very man}- textures formed by living beings, and the chemical composition of the same and multitudes of other substances, have been 90 THE BRAIN NOT A GLAND. actually ascertained and demonstrated by means now at our disposal. If, therefore, the living matter pos- sessed structure, we ought to be able to demonstrate it. But, secondly, the possession of structural cha- racter, and the exhibition of chemical properties, are actually inconceivable in the case of any form of matter manifesting vital properties, and, therefore, no one w^ho was acquainted with the phenomena of living matter w^ould have suggested that it was likely to possess structure or consist of matter in the state of a definite chemical compound. Since it is at this time impossible to give a sufficient explanation of the vital phenomena of the lowest simplest forms of living matter in existence (amoeba, monera, &c.), it is not surprising that those marvellous changes occurring in the most exalted form of living matter in man's organism should remain unexplained. That the brain should be represented as a mechanico- chemical apparatus in which immaterial thought is elaborated in somewhat the same manner as a material secretion is secreted by a gland, is, however, not surprising when we take into consideration the monstrous assertions w^iich have been made and credited. Unproven and unprovable statements, such as the dictum that living things are formed by force — mind is correlated force — a mode of ordinary energy — would scarcely be worthy of notice, were it not that many dicta of the kind have been widely accepted without due consideration, and without the RECENT VIEWS RETROGRADE. 91 suspicion tliat tlicir acceptance implies and invoK-es very much that the accepter is aware of at the time he assents. Na)-, in many cases the ph)-sical views are received because it is supposed they are " in advance" of other views. lUit this is a serious mistake. The recent attempts to interpret vital phenomena by physics are terribh' retrograde. Such an interpreta- tion cannot be accepted unless well established truths which cannot be overthrown are purposely ignored, and old ideas, long since proved to be false, are received as true. The advocates of the physical doc- trine o{ life think to force us to revert to views entertained two thousand years ago, and to submit to be guided by an extinct and debasing Epicurean philosophy. This appears to be the aim, and it certainly is the tendency of the popular force philo- sophy of the present day. On the other hand, the doctrine of vitality points in an opposite direction. The mind which contem- plates vital power will naturally be led to ponder upon the spiritual. The aspirations of the mind will pro- gressively ad\ance, while the intellect increases in strength, encouraged b\' the hope that it may succeed in forming some conception of the manner in w hich ever-present, ever-active power designs, guides, and causes to be carried out the never-ceasing changes in living matter. 0)1 tJic relation of tJic Nou-Liviui:; aud Living to God. — The general conclusion which it is believed is 92 THE RELA TIOiV OF THE established by the arguments grounded on facts of observation and experiment advanced in this work is this : that between the living 2.nA the non-living there is an essential — an absolute difference. So far from being unreasonable, it would be in accordance with reason to hold that the relation of ordinary non-living matter to its Creator was not of the same order or nature as that which subsists between God and the power that influences matter in the living state. If this be so, it is also reasonable to conceive that the highest form of vital power of which we have know- ledge and experience is in some way yet more closely related to Deity than the vital power which animates the lower forms of bioplasm or living matter. Un- doubtedly all such considerations must be accounted null and void as soon as the phenomena manifested by every kind of living matter shall have been fully ex- plained by ordinary forces and by the properties of the material particles of non-living matter ! But since at this time the aid of the hypothesis of vitality, or some other such hypothesis, is required to account for the facts of life, not only is it justifiable to extend our speculations in the direction indicated, but it is for many reasons most desirable that we should do so. We are led to suppose by the facts known to us that the properties belonging to the different kinds of non-living matter were communicated to it at its origin, and that each elementary molecule of non- living matter has since retained and will ever retain LIVING AND NON-LIVING TO GOD. 93 its special characteristic endowments. On the other hand it is conceivable, nay, the conclusion is almost forced upon us, that the peculiar vital properties or powers with which li\'in<; matter is endowed were not acquired until after, perhaps not until \\:xy long after, the creation of the matter itself There is indeed distinct evidence of the existence of vital j)()wer of many different kinds, and of change in power acquired during the transmission of vitalit}' from particle to particle, as well as of alteration in the proportion of matter animated during any given time. It is certain that the inorganic properties and forces have remained the same from the first bejjin- ning, and can never be added to or reduced, while it is equally certain that vitalit}- has varied remarkably in quality and distribution at different periods. It is possible for us to conceive an entire cessation of \italit\' — complete extinction of life after its introduction ; but we cannot conceive of the extinction of matter and its forces after the}' have once been created. No true analogy can be shown to subsist between the different properties and forces of non-living matter and the different vital powers manifested by the various kinds of living matter. The difference between copper and sih er is a difference which exhibits no analog)' what- ever, and is not comparable with, being in its nature dis- tinct from, the differential characters that distinguish, for instance, the cabbage from the oak. But tlie very matter that was once cabbage might become at a future 94 CESS A TION OF LIFE. period of time oak. But it is, at least at this time, in- conceivable that even in the most distant future, and under any conceivable alteration of conditions, copper should become silver, or tin assume the characters of lead. In the one case there are indeed differences of form, structure, character, numerous and remarkable enough, without differences in substance, which will account for the fact ; in the other there is difference in substance in the very matter itself If all life upon the earth were to cease, the pro- perties and forces of the material particles would still be retained. In that case the relations and combina- tions of the elements would be altered, but any trans- mutation in the matter itself would not occur. Nor is there reason to think that the relation of our planet to other worlds would be in the slightest degree dis- turbed by such a catastrophe. The reader will naturally inquire if, granting that all existing life were completely destroyed, we are in possession of facts which would justify the conclu- sion that life would at some future time recommence. It may be answered so far from this being the case we have ample evidence to lead us to adopt the very opposite conclusion — that life would never reappear unless some power able to overcome ordinary tenden- cies and capable of setting at nought natural laws intervened. The idea of life is, then, distinct from the idea of force, property, or matter. Living ?ind. formed are two distinct qualities of matter which cannot co- STATES OF MATTER OF LIVING BEINGS. 95 exist in the same particles at the same time. Bioplasm may acquire the properties o{ formed matter, l)ut to do so it must die — it must lose its vitality. We hav^e to notice three states of matter as regards living beings — I. The formless non-living state ; 2. The living state ; and, 3. Tlie formed state, in which the matter has acquired certain new characters and endowments, and perhaps exhibits some peculiar form which was impressed upon it by vitality. The {ox\\\ and struc- ture of the matter in this formed state may be accepted as proof that the very matter was once a part of a being that lived — that it once lived, and that its properties and form resulted directly from the action of vital power. Vitality is as distinct from matter and material pro- perties as is ever- active mind from the inanimate passive substance which it fashions, and upon which it may impress its own fleeting, and perhaps but momentar}' conceptions. The many efforts made to prove that vitality is but a mode of force have been as futile as the attempts to show that niintl is a property, or a consequence of the changes in, the atoms, whose movements are but the results of its influence and a proof of its presence. If these who try to make us believe that vitality is derived from the ordinary properties of matter were consistent, they would endeavour to instil the doctrine that the maker of a machine was a consequence of 96 THEORY OF VITALITY. the properties of the materials employed in its con- struction, and that by its action its constructor was evolved. Lastly, it may be remarked that the facts hitherto discovered by physiological observation and experi- ment do not in any way conflict with religious thought. At this very time there would indeed be no inconsistency in holding that a most devout believer and eminent theologian might be at the same time an advanced student in physiological knowledge. Many statements recently urged with consummate dogmatism by physicists who use very decided lan- guage, but have had no experience whatever in other than physical investigation, are undoubtedly incom- patible with the acceptance of any religious beliefs, but it has been shown that many of these statements are unworthy of credit, and cannot be proved to rest upon any foundation in fact. After having gained an artificial and forced notoriety they will be discarded as worthless except by the few who have determined to entertain particular scientific views irrespective of evidence. A theory of vitality (non-material, psychical) will alone enable anyone to account for the facts demon- strated in connection with the life of all living things. Although an immaterial agency cannot be v demon- strated to the senses, the evidences of the working of such a power are so distinct and clear to the reason that the mind which remains unfettered by the tram- TIIROR y OF J yTA LTTY. (^ 7 mels of dogmatic physics, and is free to exercise judg- ment, will not den}' its existence. Although the mental vital action is the highest manifestation of vital power of which we have any cognizance, it is not perhaps b)' any means the highest manifestation of which the human mind is able to conceive. As all vital power affects the molecules of matter, and makes them take up certain positions, and so arranges them that certain definite combina- tions shall take place, we ma\' surely conceive the existence of a vital power capable of causing the particles it guides to be so arranged as to form at length complex, and it may be very elaborate struc- tures, performing the most delicate work, and in a most perfect manner. Such arguments, it seems to mc, further justify a belief in the operation of a higher agency whose power transcends that of mind in as great a degree as this last transcends ordinary vitality. It is by following out such a line of thought that we ma}'. 1 think, hope to obtain, e\en from tliis lower physiological stand-point, some dim conception, it may be, of the nature of Deity, and some idea of the relation of Deity to man's scjul and l)()d}', to the various grades of lower life, and ti) matter in the nr)n-living state. Harrhon nnJ \iins Prinlrri in Ordii>nr\ in Hrr Mnir.tv Si \fnitin\ liinr. NEW ILLUSTRATED WORKS. (BY THE SAME AUTHOR.) ON VITAL PHENOMENA, AND ON THE MINUTE STRUCTURE OF LIVING BEINGS IN HEALTH AND DISEASE. These Works are all illustrated with Coloured IMates, and treat of subjects of great importance to the progress of I'hysiology and Medicine, technical terms being as much as possible avoided. Of this Skriks the kollowinc are alrkady Puiu.ishkd. SLYtuid /uiitioii, z'L'rv initch eit!ar;^ct{^ Gs. 6r/. 1. LIFE, MATTER, AND MIND ; OR PROTOPLASM. With Original Observations on Minute Structure aiiood by the Author himself or under his immediate superintendence. London : J. cV A. ClICRCllILL. %th- Thousand, 21 s. HOAAT TO ^WORK AA^ITH THE MICROSCOPE. The Fourth Edition, very much enlarged. This work is a complete manual of microscopical manipulation, and contains a full description of many new processes of investigation, with directions for examining objects under the highest powers. With Sez'enty Plates, tJidiidiug many new Figures, some ofivhich are coloured. CONTENTS :— I. The Simple and Compound Microscope — Choice of a Microscope- Travelling and Dissecting Microscopes — Clinical, Pocket, and Class Microscopes. 11. Examination of Objects by Reflected, Transmitted, and Polarized Light — Dark ground Illumination — Illumination — On Drawing and Measuring Objects — Ascertaining the Magnifying Power of Object Glasses. III. Instruments required for Dissection — Valentin's Knife, &c. — Cements — Preservative Solutions. IV. On making Cells — Brunswick Black, and different forms of Glass and other Cells for preserving Specimens. V. On examining objects in the Microscope— Muscular Tissue — Of making Minute Dissections — Hardening Textures — Of examining Objects in Air, Water, and Canada Balsam. VI. Of Preserving different Structures permanently — Of separating Deposits from Fluids. VII. Of Injecting — Apparatus, &c. — Of Natural and Artificial Injections — Of the advantage<= of Transparent Injections — Of the Prussian Blue Injecting Fluid — Injecting Mollusca, Insects, &c. VIII. Of the use of Chemical Reagents in Microscopical Investigation — Fallacies to be guarded against — Presence of Extraneous Substances. IX. Of taking Photographs of Objects. X. New method of preparing all Tissues for Microscopical Investigation. XI. On the use of very high Magnifying Powers. XII. Of making and recording Microscopical Ol^servations. Tables for practising the use of the Microscope and Manipulation. Apparatus required in Microscopical Investigation. Microscope Makers, Preparers of Specimens, Artists, Printers, Litho- graphers, &c. "The Author, both in the text and in the explanations of the engravings, has endeavoured to restrict himself, as. far as possible, to giving hints and directions which may be practically useful to the student while lie is at work." — Extract from the Preface, HARRISON, PALL MALL. ii.