Class. Book COPYRIGHT DEPOSIT A SYSTEM OF MIDWIFERY, INCLUDING THE DISEASES OF PREGNANCY AND THE PUERPERAL STATE. / BY WILLIAM LEISHMAN, M.D., REGIUS PROFESSOR OF MIDWIFERY IN THE UNIVERSITY OF GLASGOW; PHYSICIAN TO THE UNIVERSITY LYING-IN HOSPITAL; FELLOW AND LATE VICE-PRESIDENT OF THE OBSTETRICAL SOCIETY OF LONDON; CORRESPONDING MEMBER OF THE OBSTETRICAL SOCIETY OF EDINBURGH, AND OF THE OBSTETRICAL AND GYNAECOLOGICAL SOCIETY OF BERLIN, ETC., ETC., ETC. SECOND AMERICAN FROM THE SECOND AND REVISED ENGLISH EDITION WITH ADDITIONS BY JOHN S. PA KEY, M.D., OBSTETRICIAN TO THE PHILADELPHIA HOSPITAL; VICE-PRESIDENT OF THE OBSTETRICAL SOCIETY OF PHILADELPHIA, ETC. PHILADELPHIA: HENRY C. LEA. 18 7 5. Entered according to Act of Congress, in the year 1875, By HENRY C. LEA, In the office of the Librarian of Congress, at Washington, D. C. SHERMAN & CO., PRINTERS, PHILADELPHIA. o- EDITOR'S PREFACE. In preparing for the press the Second American Edition of Dr. Leishman's System of Midwifery the Editor has added such notes only as he believed would make the book more useful to the profession in this country. The additions are distinguished from the text by being inclosed in brackets, [ — P.], and will be found chiefly in the chapters on the Use of the Forceps, Lactation, and the Puerperal Dis- eases. A chapter on Diphtheria of Puerperal Wounds has been added, and a few new illustrations have been introduced, representing the principal modifications of Obstetrical Instruments generally employed in this country. The Editor trusts that these additions will increase the usefulness of a work of which the value is attested by the simultaneous exhaustion of both the English and American Editions. J. S. P. 1513 Arch Street, Philadelphia, December, 1875. PREFACE TO THE SECOND EDITION. The success which has attended the publication of this Work may, it is hoped, be accepted as an indication that it has, in some degree, fulfilled the purpose with which it was designed. In the present Edition, many errors have been corrected, and no effort has been spared to render it more worthy of the approbation which has been accorded to it. The chief alterations will be found in the Physiological Section — in regard to which the Author is under great obligation to his colleague, Professor Allen Thomson — and in the chapters on Puerperal Fever, which have been re-written, with the view of giving greater prominence to the doctrine of septicemic infection. The assistance of Dr. Gavin P. Tennent has again been invaluable, and especially so in the rearrangement of a Copious Index. 11 Woodside Crescent, Glasgow, October 1st, 1875. PREFACE TO THE FIRST EDITION. The Author's object in this Work has been to furnish the Students and Practitioners a Complete System of the Midwifery of the present day. Its claim to a title so ambitious may be questioned. Of English Text-Books, some of the very best have long been out of print; some are out of date; and others arc mere Handbooks, in which the subject is, however ably, but cursorily treated. In our language, scarcely a modern work exists which can be compared with those of Cazeaux and Scanzoni. This is the Author's apology for an attempt in which, while he does not presume to emulate those authors, he ventures to hope that the fruit of some earnest labor, but too scant leisure, may not be held unworthy of consideration. There are, he believes, few modern works of approved merit, whether British or Foreign, with which the Author has not made himself familiar; nor has he scrupled to avail himself from these sources, of what seems to him, at any point, to contribute to the elucidation of the subject. In no case, it is hoped, has this been done without ample acknowledgment. The meagreness of statistical details, references, and illustrative cases, is a part of the original plan, adopted with the view, as far as the subject will admit, of maintaining the narrative form. To several of his colleagues, to many professional friends, and, especially, to Dr. Gavin P. Tennent, for assistance in passing the work through the press, the Author is under obligations which he cannot too warmly acknowledge. 4 Montague Place, Glasgow, July 1st, 1873. CONTENTS. CHAPTEE I. INTRODUCTORY. History of Midwifery — Hippocratic Era — Arabian School — Ambroise Pare — Mau- riceau — English Midwifery — Objections to the Practice of Midwifery considered — Comparative Anatomy of the Pelvis — The Pelvis a Tube through which the Product of Conception Passes — Parturition in the Primates; in the various Paces — The Erect Posture the Main Cause of Comparative Difficulty in the Human Species — The Human Pelvis a Curved Canal — Separation of Pelvic Articulations during Labor — Midwifery Defined, 17 CHAPTER II. THE PELVIS. Oslnnominatum : Sacrum: Coccyx — The Pelvis as a Whole : " True " and " False " — Difference between Male and Female Pelvis: at Brim; in Cavity; and at Outlet — Pelvic Articulations: (a) Pelvi-lumbar ; (b) Sacro-Coccygeal ; (c) Sac- roiliac; (d) Symphysis Pubis; (e) Obturator Ligaments; (/) Sacro-Sciatic Ligaments — Inclination of Pelvis — Axis of of the True Pelvis — Brim or Inlet — Cavity — Outlet — Pelvic Diameters— Pelvic Angles — Development of Pelvis — Certain Soft Parts connected with Pelvis ; Obturator Internus and Pyriformis Muscles; " Floor » of Pelvis, 33 CHAPTER III. FEMALE ORGANS OF GENERATION. A. External. Labia; Perineum; Hymen, etc. — Erectile Tissue — The Vagina — Glands of the External Organs— Abnormal Conditions — Mammary Glands. B. Internal. The Uterus : Situation of; Divided into Body and Cervix; Axis of Unimpregnatcd Uterus ; Cavity of; Fundus; Surfaces and Borders ; Serous Covering of — Broad Ligaments; Round Ligaments; Vesico-Uterine Folds — The Fallopian Tubes — Parovarium — Folds of Douglas — Equilibrium of the Uterus, 48 CHAPTER IV. female organs of generation (Continued). Of the Proper Tissue of the Uterus — Of the Mucous Layer : its Structure and Glands, in the Body and Cervix — Bloodvessels of the Uterus — Lymphatics and Nerves — Malformations and Abnormal Conditions— The Ovaries : their Structure — Vlll CONTENTS. The Graafian Vesicles and their Development — The Ovum — Phenomena of Ovulation — Formation of the Corpus Luteum — The Corpus Luteum of Preg- nancy distinguished, 67 CHAPTEE V. MENSTRUATION AND CONCEPTION. The "Rut" of Mammalia: Analogy between this and Menstruation — The First Menstrual Period: Statistics of Duration of a " Period "—Quantity of the Discharge — Menstruation a Hemorrhage : Non-Coagulability of — Source of the Menses: various Theories regarding : is from the Mucous Membrane of the cavity — Pouchet's Theory examined ; is the Mucous Membrane shed ? — Views of Kolliker, Coste, etc. — Duration of Childbearing Epoch — Cause of Men- struation — Conception — Composition of the Semen — Spermatozoa and their development — " Sperm Cells " — The function of the Germinal Vesicle ; " Germ Cells " — How does the Semen reach the Ovum? 87 CHAPTER VI. DEVELOPMENT OF THE OVUM. Formation of the Embryo-cell — Cleavage of the Yolk — Development of Blasto- dermic Vesicle — "Serous" and "Mucous" Layers — The Area Germinativa and Primitive Trace — Formation of the Embryo ; of the Umbilical Vesicle and Omphalo-mesenteric Vessels; of the Amnion; of the Allantois and Umbilical Vessels; of the Chorion — The Liquor Amnii — The Vitriform Body — The Decidua : what is it? — Decidua Vera; Eeflexa ; Serotina — Early connection of Ovum with Decidua — The Umbilical Cord : Vessels; Gelatin of Wharton, etc. — Knots on Cord — The Placenta in Birds: in Non-Placental Mammals: in Ruminants: in Man : Maternal and Foetal Surfaces of: Maternal Circula- tion in : Curling Arteries: Sinuses: Veins — Foetal Portion: Arteries: Tufts or Villi : Veins — Functions of the Placenta — Structure of Villi, . . 101 CHAPTER VII. DEVELOPMENT OF THE EMBRYO AND FOETUS. Demonstration of Embryonic Structures — Characteristics and Development of the Foetus at the termination of each Month of Pregnancy, from the third onwards — Dimensions of Mature Children — Of the Presentation and Attitude of the Child in the Womb— Causes of Cranial Presentation : theories of " Physical Gravitation," " Volition," and " Reflex Action " — The Foetal Cranium : Sutures: Fontanelles: Diameters — Definition of the term "Vertex" — Func- tions of the Foetus: Circulation: Respiration: Nutrition: Secretion, . 120 CHAPTER VIII. PREGNANCY : SIGNS OF PREGNANCY. Pregnancy — The Gravid Uterus : Muscular fibres of: Muscular layers — Change in fibres after delivery — Development and Anatomical Relations of Uterus at various stages of Pregnancy — Signs of Pregnancy — Suppression of the Cata- menia — Digestive Disorders: Morning Sickness: Salivation — Kiestein — Changes in the Mammae : Pain: Enlargement: Secretion of Milk: Areola: Changes in Nipple, and in Glandular Follicles : Secondary Areola — Enlarge- CONTENTS. IX ment and External Appearance of Abdomen : Flattening in early months : Change in the Appearance of Umbilicus: Diagnosis of other Abdominal Tumors— Vaginal Examination: Color: Digital Examination: Vaginal Pulse, 144 CHAPTER IX. signs of pregnancy (Continued). Changes in the Os and Cervix Uteri : Progressive Softening of: Characters of at Various Stages — Position of Os in Relation to Pelvic Walls — Practice of the "Toucher" — Examination per Anum — Quickening: Ecetal Movements Ob- served ; («) by the Mother, (b) by the Accoucheur — Ballottement or Repercus- sion — Foetal Pulsation — Funic Souffle — Uterine Souffle : Theories as to its Pro- duction — Stethoscopic Examination of Foetal Movements — Signs divided into Certain and Probable — Tabular Resume of the Signs of Pregnancy, . 159 CHAPTER X. DURATION OF PREGNANCY — SUPERFCETATION. Duration of Pregnancy : in Cows and Mares : in Women — Protracted Preg- nancy : Cases of — Difference in Rate of Development — Mode of Calculating the Probable Time of Delivery: Calculation from last Menstruation to be cor- rected by Period of Quickening — Superfcetation : to be distinguished from Superfecundation — Proofs of the latter — Twin Pregnancy in relation to this Subject — Cases — Conclusions, . . . , . „ , . .176 CHAPTER XI. PLURAL* PREGNANCY — EXTRA-UTERINE PREGNANCY. Plural Pregnancy — Mode of Impregnation — Twins: Disposition of the Mem- branes and Placenta in : Diagnosis of : Relation of to Superfcetation — Triplets, etc. — Extra- Uterine Pregnancy — Varieties of: Ovarian: Tubal: Tubo- Ovarian: Abdomino-Tubal: Tubo-Uterine, etc.: Abdominal — Causes of Extra- Uterine Pregnancy — Development of the Ovum and its Coverings — Sympathy of the Uterus — Symptoms — Progress of in Different Varieties : Rupture of the Sac: Peritoneal Inflammation: Discharge of Foetal Debris — Terminations — Treatment, 190 CHAPTER XII. abnormal development. Molar Pregnancy — False Moles : from Vagina : Membranous Dysmenorrhoea : Fibrous and Hemorrhagic Casts of Uterus — True Moles : Fleshy Moles : Hy- datidiform Moles — Their Pathology, Diagnosis, and Treatment — Diseases of the Placenta, and their Effects — Missed Labor — Diseases of the Foetus — Infra- Uterine Fractures and Amputations: Efforts at Reproduction — Monsters, 205 X CONTENTS. CHAPTEK XIII. DISEASES OF PREGNANCY. I. Disorders of the Digestive Functions — Excessive Vomiting: Treatment of: Question of Induction of Premature Labor in — Anorexia — Gastrodynia — Pyrosis — Constipation — Diarrhoea — II. Disorders of Respiration — Dysp- noea—Cough — III. Disorders of the Circulation— Condition of the Blood in Pregnancy: Diminution of Blood-Corpuscles : Proportional Alteration in Fibrin and Albumen — Supposed resemblance of the Phenomena of Pregnancy to those of Chlorosis — Administration of Iron in Pregnancy — Plethora — Varicose Veins — Haemorrhoids — Thrombus of the Vagina, . . . 218 CHAPTER XIV. diseases of pregnancy (Continued). IV. Disorders of Secretion and Excretion — Ptyalism — Interference with Function of Kidneys and Bladder — Retention : Mechanical or from Paralysis — Albuminuria : State of the Blood in : Peculiarities of the Puerperal Form: Connection of with Puerperal Convulsions : Symptoms, Prognosis, and Treat- ment — The Phosphatic Diathesis in Pregnancy — Leucorrhcea and Granular Vaginitis — Ascites — Dropsy of the Amnion — Hydrorrhea — V. Disorders affecting Locomotion — Pelvic Articulations : Relaxation of: Inflammation of— VI. Disorders affecting the Nervous System— Affections of the Special Senses — Effect on the Moral and Intellectual Faculties — Abdominal and Uterine Pain— VII. Displacements of the Gravid Uterus — Prolapsus — Anteversion and Anteflexion: Symptoms and Treatment of — Retroversion; how caused originally: Chronic and Acute Forms : Symptoms and Treatment of each : Operation for the Reduction of — Oblique Displacements, . . 232 CHAPTER XV. LABOR AND ITS PHENOMENA. Causes of Labor — Maturity: Antagonism between certain Groups of Uterine Fibres: Brown-Sequard's Theory : Labor coincident with the Tenth Menstrual Period — Forces by which Delivery is effected : Nervi-motor Functions of the Uterus: Effect of Emotional Causes: Reflex Function of the Spinal Cord: Peristaltic Action : Auxiliary Force in the Muscles of Expiration — Stages of Labor— Preparatory Stage— First Stage: Labor Pains; their Effects on the Maternal Pulse and on the Uterine Souffle: False Pains: Mechanism of the Dilatation of the Os ; the Bag of Waters ; Effect of Longitudinal Fibres : Termination of First Stage in Rupture of Membranes : Rigor : Show— Second Stage : Change in character of the Pains ; the " Caput Succedaneum :" Action of Voluntary Muscles : Dilatation of the Perineum : Birth of the Head and Trunk— Third Stage : "Dolores Cruenti :" Separation and Expulsion of the Placenta ; Mechanism of this, ........ 252 CHAPTER XVI. MANAGEMENT OF NATURAL LABOR. Duties of the Accoucheur — Preliminary Arrangements — False Pains and their Treat- ment — Armamentarium of the Accoucheur — Position of the Woman during CONTENTS. XI Labor — Digital Examination : Points to be examined — The Patient not to take to bed during the First Stage — Preparation of the Bed, etc. — Abdominal Muscles to be called into play during the Second Stage — Management of the Anterior Lip of the Os — Obstacles arising from Rigid Os ; and from Non- Rupture of Membranes — Use of Stethoscope — Views regarding Support of Perineum — Treatment if Laceration is threatened — Causes of Laceration — Birth of the Head — Passage of the Trunk — Treatment of Suspended Animation in the Child — Ligature of the Cord — Management of the Third Stage: Crede's Method — Application of Abdominal Bandage — Treatment of the Woman after Delivery, 268 CHAPTER XVII. THE MECHANISM OF LABOR. Ideas which Labor involves — Difficulty and Importance of the Subject — Historical Sketch: Views of Sir Fielding Ould ; of Smellie; of Saxtorph ; of Solayres de Renhac ; and of Naegele — Natural and Faulty Presentations — Cranial Presen- tations : Occipito-Anterior and Occipito-Posterior Varieties — First Posi- tion: Pelvic Obliquity: Occipito-Frontal Obliquity, or Flexion: the Head "at the Brim :" Examination of Fontanelles and Sutures — Rotation ; Causes of — The "Presentation" or "Presenting Point" — The Caput Succedaneum — The Chin leaves the Chest — Further Descent and Birth of the Head — Obliquity at the Outlet — Moulding — External Rotation or Restitution of the Head — Second Position: the Converse of the First — Third Position — Resume of Mechanism in Occipito-Anterior Positions, 284 CHAPTER XVIII. mechanism of labor (Continued). Occipito-Posterior Positions — The Third [Fourth] Cranial Position ; Rotates into the Second, or may terminate with forehead forwards — The Fourth [Fifth] Position ; Rotates into the First, or may terminate with Forehead forwards — Artificial Rectification of these Positions [Sixth Position] — Comparative Fre- quency of the Four Cranial Positions. Face Presentations — Distinction between "Obstetrical" and "Anatomical" Face — Mento-Posterior and Mento-Anterior Varieties— Fourth Position: Mechanism of— Third Position — First Position ; Rotates into the Fourth — Second Position : Rotates into the Third — Relative Frequency of the Facial Positions — Operative Interference in — Irregular Presentations — Tabular Com- parison of Cranial and Facial Positions, 303 CHAPTER XIX. PELVIC PRESENTATIONS. The Practice of the Past — The Pelvis a Natural Presentation — Dorso-Anterior and Dorso-Posterior Positions — Breech Presentation ; Four Positions of — First Position of the Breech: Rotation: Passage of the Buttocks: Descent and Birth of the Shoulders: Difficult Progress of the Head, and Mechanism of its Expulsion — Second Position of the Breech — Third Position of the Breech : Birth of the lower portion of the Trunk, and of the Shoulders i Xll CONTENTS. Kotation of the Face backwards, and Mechanism of the Birth of the Head; Exceptional Terminations— Fourth Position of the Breech— Special Kisk of Pelvic Presentations — Diagnosis and Peculiarities — Knee and Footling Cases — Management of Pelvic Presentations — Nature of Assistance to be Rendered — Use of the Fillet, Yectis, and Blunt Hook — Indiscriminate Dragging on the Lower Limbs to be avoided — Treatment of Case where Arms pass up along- side Head — Management of the Funis — Indications of impending Death of the Child — Manipulation for effecting speedy Delivery of the Head — Use of the Forceps, 324 CHAPTER XX. transverse presentations: complicated presentations. Transverse Presentations — The Arm or Shoulder the Presenting Part — Causes of — Signs of, before and during Labor — Premature Rupture of the Membranes to be avoided^-Dorso-Anterior and Dorso-Posterior Positions — Determination of exact Position by Observation of the Hand — Probable Course of an Unaided Case — Occurrence of Spontaneous Evolution — Spontaneous Expulsion — Methods of Operative Assistance : Period of Labor to be selected : Cephalic Version : Podalic Version : Method of Combined External and Internal Manipulation: Special Difficulties — Procedure Modified if Child Dead— Compound or Com- plicated Presentations — Hand and Head— Hand and Feet, etc.— General Management of these, .......... 341 CHAPTER XXI. FUNIS PRESENTATION. " Presentation " and " Prolapse" of the Cord — Relation of the Funis to other Pres- entations — Causes of — Symptoms of at Various Stages of Labor — Great Danger to Child— Treatment: at first Expectant: avoid Rupture of the Membranes : Reposition by the Fingers : by Mechanical Appliances : Various Repositoria described: Postural Method : Use of the Forceps : Turning, . . 355 CHAPTER XXII. PREMATURE EXPULSION OP THE OVUM. Classification — Abortion ; Definition of — Causes : in General Health : from Reflex Irritation: from Diseases of the Ovum: from Action of Oxytoxics: from Af- fections of Neighboring Organs : from Mechanical Violence — Tendency to Repeated Abortion — Symptoms ; at various Periods— Precursory Symptoms : Pains : Hemorrhage— To be distinguished from Delayed Menstruation— Signs of Death of the Foetus — Distinction to be drawn between "Threatened" and " Inevitable " Abortion — Retention of the Ovum — Expulsion of the Placenta — Treatment: Preventive: Prevention when Abortion Threatened — Expulsion to be Promoted when Inevitable — Management of Haemorrhage, and of the Pla- centa: Placental Forceps — Treatment of a Woman after Abortion — Prema- ture Labor — Special Causes— Treatment, 367 CHAPTER XXIII. HEMORRHAGE before delivery. "Unavoidable" and "Accidental" Haemorrhage — Placenta Previa; Central and Lateral : Original Idea as to the nature of: Views of Roederer and Rigby CONTENTS. Xlll — Causes of Placental Presentation — Symptoms :. Hemorrhage before and during Labor : Examination from the Vagina : Occasional Termination by- Expulsion of the Placenta, with Cessation of Haemorrhage : Symptoms and Termination of the " Lateral " Variety — Treatment: General Measures: Use of the Plug or Tampon : Evacuation of the Liquor Amnii by Puncture of the Membranes or Placenta — Turning in Placenta Prsevia : Passage of the Hand through the Placenta at one time Practiced: Usual Method of Operation — The Bi-Polar Method — Artificial Extraction of the Placenta: Simpson's Statistics — Partial Separation of the Placenta: Barnes's Views — General Conclusions as to Treatment — Accidental Hemorrhage; more serious than is generally supposed — Site of the Placenta — Symptoms — Treatment — Use of Styptics in both Forms of Haemorrhage, . . . . . . . ' . 386 CHAPTEE XXIV. HAEMORRHAGE AFTER DELIVERY. Haemorrhage in the Third Stage of Labor — Abnormal and Ketained Placenta, and Irregular Uterine Contraction, as Causes of Flooding — Post-partum Hemor- rhage — Causes; General and Local — Symptoms; of External and Internal Haemorrhage: Examination of the Abdominal "Walls: Examination by the Vagina : General Symptoms : Symptoms which indicate the Approach of Death — Treatment; Prevention: Treatment during the Hemorrhage: Pres- sure and Friction over the Uterine Kegion — Effects of Bandaging — Effect of Passing the Hand into the Uterine Cavit}' — Application of Cold, should not be Continuous — Astringents to Internal Surface — Galvanism — Ergot — Treatment by Plugging abandoned — Views in regard to Compression of the Abdominal Aorta — Application of the Perchloride of Iron and other Styptics : Objections to, and Arguments in favor of this Procedure — Dr. Barnes's Process — Treat- ment directed to the General Condition of the Patient — Effects of Rest and Position — Reaction to be avoided after severe Flooding — Transfusion : The "Mediate" and " Immediate " Processes: Dr. Aveling's Apparatus; Injec- tion of Defibrinated Blood, and of Saline Solutions, ..... 404 CHAPTER XXV. INVERSION OF THE UTERUS. Varieties of Inversion : Three Stages of the Ordinary Variety — Inversion of the Unimpregnated Uterus — Inversion usually occurs during the Third Stage of Labor — Causes: Dragging upon the Cord: Shortness of the Cord : Irregular Contraction of the Uterus — Connection of this Accident with Hour-Glass Con- traction — Effects of Paralysis of the Fundus — Mechanism of the Displacement — Symptoms: Peculiar Violence of the Shock: Haemorrhage: Absence of Tu- mor in Hypogastrium — To be distinguished from a Fibrous Polypus — Sensibil- ity and Occasional Contractility of the Tumor — Modes of proving the Absence of the Uterus from its Normal Situation — Recurrence of Haemorrhage in Chronic Inversion — Treatment: Ordinary Method of Replacement : Manage- ment of the Placenta if still Adherent: Management of more Difficult Cases: Compression of Tumor: Depaul's Instrument — Chronic Inversion: Mont- gomery's Method of Reposition: Constriction of the Os must be Overcome: Effects of Sustained Elastic Pressure — Division of the Stricture : Removal by the Ecraseur — Thomas's Operation as substitute for removal, . . . 418 XIV CONTENTS. CHAPTER XXVI. RUPTURE OF THE UTERUS. Rupture during Pregnancy — Rupture during Labor — Partial or Incomplete Rup- ture — Site, Extent, and Direction of the Laceration — Reason of the Compara- tive Frequency of Cervical Rupture — Is Rupture less common in Primiparae? — Effect of the Duration of Labor — Causes — A. Mechanical : Sex ; Pelvic De- formity ; Faulty Presentation ; Pressure upon the Cervix ; Operative Vio- lence ; Effect; Violent Uterine Action — B. Reflex: Excitement of Cervix, etc. — C. Pathological: Cancer; Rigidity of the Os ; Thinning or Partial Atrophy; Softening; Fatty Degeneration — Symptoms — Premonitory: Local- ized Pain increased during Labor — Signs of Rupture: Pain; Haemorrhage; Shock; Recession of the Presenting Part — Laceration involving the Vagina — Treatment — Preventive Measures : Delivery by the Forceps or b}' Perforation — Extraction of the Placenta — Hernia of the Intestine — If Foetus has escaped into the Peritoneal Cavity, Turning recommended : Gastrotomy is, however, to be preferred — Further Management of the Case — Treatment of Rupture of the Uterus in various Stages of Pregnancy, 430 CHAPTER XXVII. DEFORMITIES OF THE PELVIS. Importance of the Subject — Classification of Deformities — Causes — Diseases affect- ing the Pelvis : Rachitis: Malacosteon — Rickets and Malacosteon contrasted : Nature of the Brim Deformity characteristic of Each — Possibility of Yielding in a Malacosteon Pelvis — The Obliquely Distorted Pelvis — Deformities of the Cavity : Flattening of the Sacrum : Funnel-shaped Pelvis — Distortion of the Outlet : Approximation of the Tuberosities of the Ischia : Projection Forwards of the Coccyx : Anchylosis of the Sacro-coccygeal Articulation — Masculine Type of Pelvis — Infantile Type — Effect of Muscular Action in producing Pelvic Distortion— Spondylolisthesis — Pelvis JEquabilker-justo-Major, and justo-Minor — Obstruction from Exostosis, O.-teo-Sarcoma, and other tumors, and from Fractures of the Pelvis, and Morbus Coxarius — Symptoms — Measure- ments of the Pelvis: Pelvimeters — Examination by the Fingers — Effects of Distortion — Difference between "Impaction" and "Arrest" — Treatment — Prevention — Circumstances which call for the Forceps, Turning, Craniotomy — Use of the Forceps in Deformed Pelvis — Caesarian Section, . . . 443 CHAPTER XXVIII. THE FORCEPS. History of the Forceps — Chambei-len's Forceps — Invention of the Pelvic Curve — The Short Forceps: Cases to which it is Applicable — Reasons for preferring the Straight Forceps in most Cases — Forceps in Use in America— Circumstances in which the Forceps is Required — Application of the Forceps : Conditions essential to safety: Degree of Dilatation of the Os : Is it necessary to feel an Ear ? Membranes to be ruptured : Blades to be applied to the Sides of the- Head : Forceps to be applied in the Opposite Oblique Diameter to that occupied by the Head of the Child — The Operation : Introduction of the " Lower " and " Upper" Blades in the First Cranial Position — Application to the other Cra- nial Positions, 460 CONTENTS. XV CHAPTER XXIX. the forceps (Continued). Action of the Forceps: 1, by Compression; 2, by Traction; 3, by Double-Lever Action — Mode of Extraction: Management and Direction of the Handles at various Stages of Delivery — Delivery by the Forceps in Occipito-Posterior Positions : Rotation by the Forceps : Extraction with the Forehead Forwards — The " Long Forceps " — Reasons for Preferring the Pelvic Curve in this Ope- ration — Description of the Instrument — Cases in which the Long Forceps is applicable — Directions for the Operation : Blades to be applied to the Sides of the Pelvis: Mode of Introduction of the Lower and Upper Blades: Relation of the Blades to the Surface of the Cranium — Use of the Forceps in Presenta- tions of the Face — Procedure when the Head is retained after Expulsion of the Trunk — Modifications of the Instrument : Ziegler's, Radford's, and other For- ceps, 479 CHAPTER XXX. THE VECTIS; FILLET; BLUNT HOOK; ETC.: DECAPITATION. Discovery of the Vectis by Roonhuysen : Mode of Using the Vectis — Cases to which it may be Applied — The Fillet ; a Contrivance of Ancient Origin ; Applicable chiefly to Breech Cases — The Blunt Hook — The Crotchet : Pre- cautions necessary in the Use of the Crotchet: The Guarded Crotchet — Use of two Crotchets — Decapitation ; Various Instruments for : Description of the Operation : Extraction of the Trunk : Subsequent Extraction of the Head by the Various Methods of the Forceps, Crotchet, or Cephalotribe, . . 500 CHAPTER XXXL TURNING. Various Methods of Turning: Turning as practiced by the Ancients: Podalic Version — Circumstances which call for and Conditions favorable to the Opera- tion : The Operation in Detail : Choice of Hands : Introduction of the Hand : Passage of the Os : Seizure of a Foot or Knee — Circumstances which render Turning Difficult: Difficulty in Seizing the Foot — Child to be Turned For- wards — Management of the Case after Version — Pelvic Version — Cephalic Version — Turning in Contracted Pelvis: Degree of Distortion which may admit of Turning — Turning contrasted with the Long Forceps, and. as a Sub- stitute for Craniotomy — Special Difficulties — Bimanual or Bipolar Version : Processes of Wigand, Lee, and Braxton Hicks, 510 CHAPTER XXXII. EMBRYOTOMY. Conditions which warrant the Operation — Craniotomy : consists of Various Stages — Perforation: Varieties of Perforators: Method of, and Precautions to be Observed in Perforating — Cranial Contents to be Broken Up and Dislodged — Traction to be now Employed — Use of the Crotchet : where to Fix it : Dangers of — The Guarded Crotchet — The Craniotomy Forceps — Removal of the Vault of the Cranium — Protection of the Maternal Tissues — Davis's Osteotomist — XVI CONTENTS. The Scalp to be Preserved — Turning after Craniotomy — Canting the Base, after Eemoval of the Flat Bones, .and bringing the Face Downwards — The Cepha- lotribe: French and English Models — Cephalotripsy the Final Stage in the Operation of Craniotomy — Details of the Operation — May the Cephalotribe be used as a Tractor? — Subsequent Extraction of the Trunk — Craniotomy in Breech Delivery, after the Passage of the Trunk — Embryulcia: Evisceration of the Foetus: applicable chiefly to Impacted Transverse Presentations — Van Huevel's Forceps Saw — Dr. Barnes's process of Cranial Section by the Ecra- seur, 526 CHAPTER XXXIII. HYSTEROTOMY and allied operations. History of the Operation of Hysterotomy — Cases in which it is Justifiable: Mater- nal Mortality : Different Results in British and Continental Practice — Conditions favorable to Success — The Operation and its Details: Duties of the Assistants: Closure of the Wounds — After-Treatment — Causes of Fatal Result — Effect of Cold in preventing Peritonitis — Repeated Success of the Operation in the same Cases — G-astrotomy : Cases in which the Operation is required — The so-called Vaginal Caesarian Section— Symphysiotomy : History and Nature of this Operation : Objections to it — Stoltz's Operation of Pubiotomy — Tabular State- ment showing the Degree of conjugate Contraction at the Brim which may be supposed to indicate respectively the Operations of the Long Forceps, Turning, Embryotomy, and the Caasarian Section, ....... 545 CHAPTER XXXIV. induction or premature labor. History "of the Subject — Nature and Scope of the Operation — Viability or Non- Viability of the Child — Conditions which justify the Operation — Various Methods of Provoking Uterine Action: Ergot: Puncturing the Membrane: Separation of the Membranes by Hamilton's Method : Dilatation of the Cervix by Tents : Introduction of an Elastic Bougie or Catheter into the Uterus : Plugging or Distending the Vagina: The Method of Kiwisch by the Vaginal Douche: Cohen's Method by Irttra-uterine Injections: Dr. Barnes's Process, consisting of a " Provocative " and an " Accelerative " Stage : Galvanism : Ir- ritation of the Breasts — Anatomical and Physiological Fitness of the Parts — Constitutional Influences, .......... 558 CHAPTER XXXV. labor obstructed by maternal soft parts. Rigidity of the Os : Use of Belladonna : Forcible Distension : Incision of Os Oc- cluded — Effects of Uterine Displacement — Abnormal Conditions of the Vulva and of the Vagina: Rigidity : Persistent Hymen : Cicatrices from Sloughing : Treatment of these Conditions — Vaginal Thrombus — Uterine Polypus : Man- agement of, where it obstructs Labor — Ovarian Tumors — Fcecal Accumulation in the Rectum : Rectocele — Distension of the Bladder : Cystocele — Stone in the Bladder an Occasional Impediment — Hernial — Other Tumors which may im- pede Labor — Malignant Disease of the Canal, 570 CONTENTS. XV11 CHAPTER XXXYI. OBSTRUCTION DEPENDING ON THE STATE OF THE OVUM. Hydrocephalus: Diagnosis of: Management of such Cases — Spina Bifida — Obstruc- tion from Ascites, Hydrothorax, and Distension of the Bladder — Gaseous Dis- tension from Putrefaction — Tumors springing from the Foetus — Anchylosis of the Joints, and Intra-uterine Fracture — Premature Closure of the Sutures — Unusual Development of the Foetus — Special Difficulties in Plural Pregnancy: Locked Twins — Monsters which impede Delivery ; The Siamese Twins, and other Similar Cases — Shortness of the Umbilical Cord as an Obstacle — Dorsal Displacement of the Arm — Thickness and Persistence of the Membranes, 582 CHAPTER XXXVII. UTERINE INERTIA. AND PRECIPITATE LABOR. Irregularities in the Progress of Labor ; often due to Intestinal Derangement — Inertia : Influence of Temperament, Climate, Age, Emotion, Excessive Dis- tension, Premature Rupture of the Membranes, etc. — Influence of Irregular Uterine Action ; Uterine Tetanus — Wigand's Classification : Different Grades and Varieties of Inertia — Treatment of Inertia ; if from Over-distension or Displacement of the Uterus ; if from Intestinal Derangement — Various Modes of Exciting Reflex Uterine Energy — Stimulants as a rule to be avoided — Use of the Forceps in Inertia — Ergot ; its Natural History, and Physiological Effects : Rules for its use in Midwifery — Other Oxytoxic Agents — Precipitate Labor: Causes obscure : Apparent Connection with Menstrual Excitement — Labor may be Precipitate from Deficient Resistance — Danger of Rupture and Laceration of the Uterus — Tendency to Post-partum Haemorrhage — Treatment: Empty Bowels : Opium : Sources of Reflex Irritation to be carefully avoided, . 594 CHAPTER XXXVIII. THE PUERPERAL STATE : LACTATION. Management of the Puerperal State — The Lochia : Nature and Source of — After- pains : Treatment of — The Lacteal Secretion : Milk Fever : Colostrum — The Child to be put to the Breast at Fixed Intervals — Agalactia — Galactorrhea : Two varieties of — Management of Lactation — Effects of Over-feeding — Dura- tion of Lactation — Effects of Menstruation and Pregnancy upon Lactation — Disorders of Lactation — Inflammation and Abscess of the Mamma : Effects of: Treatment — Excoriation and Fissure of the Nipples : Prevention of; Treat- ment of, . .607 CHAPTER XXXIX. THE NEWLY BORN CHILD. Management of the Cord — Clothing — Cleanliness — Light and Air — Colostrum : Im- proper use of Laxatives — The Mother to Nurse if Possible — Selection of Hired Nurses; their Diet and Regimen — Causes of Difficulty in Sucking — Congenital Malformations — The Excretory Functions — Diarrhoea: Simpleor " Catarrhal," and Inflammatory or " Dysenteric " Varieties : Treatment of Each — Constipa- tion: Management of — Icterus Neonatorum — Thrush — Artificial Feeding: XV111 CONTENTS. Substitutes for Breast-Milk: Cow's Milk, Diluted and Sweetened: Nursing- Bottles: Nurse to be procured if Child does not Thrive: Other Articles of Diet ; Liebig's Food for Infants — Weaning — Dentition, . . . 626 CHAPTER XL. PHLEGMASIA DOLEXS. The Puerperal State in its Relation to Disease — Phlegmasia Dolens : Nomen- clature — Causes ; after Labor and when Unconnected with Delivery — Symp- toms : Premonitory Signs : Pain : White Swelling : Tension : Heat : Constitu- tional Symptoms : The Limb Pits on Pressure during Convalescence : Loss of Power in the Limb — Morbid Anatomy: Character of the Effused Fluid : Plug- ging of the Veins ; State of the Lymphatics — Pathology: Milk-leg: Angeio- leucitis : Crural Phlebitis : Experiments of McKenzie and H. Lee : Views of Tilbury Fox : Review of the Pathology of the Subject — Treatment ; Is Blood- letting justifiable? Blisters: Bandaging: Is Contagion Possible? General Treatment to be directed as a rule to a Condition of Debility : Tonic Regimen : Antiseptic Remedies — Cause of Protracted Convalescence, . . . 642 CHAPTER XLI. PUERPERAL INSANITY. Nomenclature — Normal Effect of Pregnancy on the Mind — Insanity associated with Pregnancy, Labor, or Lactation — True Puerperal Insanity : Pathological Theories : Connection of Puerperal Insanity with Albuminuria — Puerperal Mania: to be distinguished from Phrenitis : is essentially a Disease of Exhaus- tion — Symptoms: Significance of a Rapid Pulse : Violence: Delusions — Prog- nosis — Puerperal Melancholia : Distinguishing Characteristics : Probable Ter- minations — Treatment: Prevention: Bloodletting to be Avoided: Manage- ment of the Digestive Functions: Emetics: Vascular Sedatives: Nervous Sedatives; Opium, Hyoscyamus, Chloral, etc. : Diet and Regimen: Seclusion and Restraint: Treatment during Convalescence: Tendency to Recurrence after Subsequent Labors, 658 CHAPTER XLII. PUERPERAL ECLAMPSIA. Definition — Connection between Eclampsia and Acute Bright's Disease — Eclampsia from other Morbid Conditions — Effects of Pregnancy on the System — Period of Explosion — Symptoms : Premonitory Signs ; (Edema, Albuminuria, Cephal- algia, etc. — Phenomena of the Fit: Period of Tonic and Clonic Convulsions, and of Coma — Pathology : Albuminuria : Decomposition of Urea, and Forma- tion in the Blood of Carbonate of Ammonia : Effects of Pressure on the Renal Veins : Detection of Albumen in the Urine — Morbid Anatomy — Effect of La- bor Pains — Maternal and Foetal Mortality — Prognosis: in Eclampsia Gravi- darum, Parturentium, et Puerperarum — Treatment: Prophylaxis: Use of Acids: Purgatives and Diuretics : Induction of Premature Labor : Treatment during the Fit: Bloodletting; Chloroform; Chloral: Obstetrical Treatment at Various Stages of Labor; Acceleration; Rupture of the Membranes ; Use of the Forceps, 672 CONTENTS. XIX CHAPTER XLIII. PUERPERAL EEYER AND ALLIED AFFECTIONS. Perplexing Nature of the Subject — Puerperal Fever : Does a Specific Puerperal Poison really exist? — Should the term "Puerperal Fever" be retained? — Metria — Physiological Peculiarities of the Puerperal State — Puerperal Septi- caemia — Mode of Septic Poisoning — Connection with certain Zymotic Influ- ences; Erysipelas, Small-Pox, Scarlet Fever, etc. — Connection with Post- partum Inflammations — Puerperal Peritonitis ; May exist independently of Puerperal Fever: Symptoms of an Ordinary Attack; of the more Severe form — False Peritonitis — Puerperal Metritis ; of less Frequent Occur- rence : Symptoms — Uterine Phlebitis; Symptoms at first Obscure: Sec- ondary Abscesses in the Later Stage: Tissues chiefly involved — Vaginitis; Sthenic and Asthenic — Inflammation of the Uterine Lymphatics, . . 687 CHAPTER XLIY. puerperal fever, etc. (Continued). Question of Contagion — Septicemic Infection — Other Specific Poisons — Are Inflam- matory Cases Contagious ? — History of Epidemics — Symptoms of Puerperal Fever — Morbid Anatomy : Malignant and other Varieties Contrasted : Lesions of other Organs : Pathological Appearances no Indication of the Virulence of the Attack — Evidence of a Change of Type in Puerperal Fevers — Treatment : All Varieties to be Treated as if Contagious : Recorded Results of Bloodletting and Purging: Gooch's Treatment: Connection of Metastatic Inflammation with Thrombus and Embolism : Uterine Phlebitis : Purulent Formations ; Effect of Emetics; Calomel and Opium; Turpentine; Blisters and External Applications; Tonic and Stimulant Treatment: Tapping the Peritoneum: Prophylactic Treatment : Cleanliness : Use of Antiseptics, . . . 701 CHAPTER XLV. DIPHTHERIA OF PUERPERAL "WOUNDS. Prevalence during the past five years — Symptoms — Those which precede the out- break — Digestive System — Pain and Abdominal Tenderness — Pulse and Res- piration — Temperature — Countenance — Mental Condition — Local Symptoms — False Membrane on Wounds — Joint Complications — Diagnosis and Prognosis — Pathological Anatomy — Nature — Causes — Treatment: Quinia: Opium: Local Remedies : Cauterization of Diphtheritic Wounds : Vaginal and Intra- uterine Injections : Prophylaxis, ........ 719 CHAPTER XLVI. PELVI-PERITONITIS : SUDDEN DEATH IN PUERPERAL PERIOD : ANAESTHESIA. Pelvi-Peritonitis — Inflammation of the Uterine Appendages— " Fulness," " Hardness," and " Tumor " — Pelvic Cellulitis : Anatomy of the Pelvic Cellu- lar Tissue — Bernutz on Pelvi-Peritonitis — Diagnosis of Pelvic Cellulitis and Pelvi-Peritonitis — Engorgement of the Uterus — Detection of Pus: Fluctuation — Treatment : Alleviation of Pain : Application of Leeches, Poultices, Fomen- XX CONTENTS. tations, etc. : Methods of Promoting Absorption ; Mercury; Iodine; Counter- irritation ; The Operative Treatment of Abscess — Peri-uterine Hematocele — Sudden" Death in Puerperal Period: Embolism of Pulmonary Artery — Arterial Embolism — Entrance of Air into Veins — Anaesthesia : Various Anaesthetic Agents : Effects of Chloroform on the Blood, and on the Progress of Labor : Disadvantages of Chloroform : Modern Practice, . . . 730 APPENDIX, 745 INDEX, 753 LIST OF ILLUSTRATIONS. FIG. 1. Pelvis of the female guinea-pis:, . ....... 2. The same; showing the separation of the bones during parturition, 3. Diagram showing the direction in which the uterine contents gravitate in the Mammalia generally, ........ 4. Diagram showing the oscillatory movement referred to (Matthews Duncan), ........... 5. External surface of right os innominatum, ..... 6. Internal surface of the same bone, ....... 7. Sacrum and coccyx — internal surface, ...... 8. 9. Male and female pelves contrasted, as seen from before (Quain), . 10, 11. Male and female pelves contrasted, as viewed in the axis of the brim (Quain), ............ 12. Internal surface of female pelvis, showing — 1, 2, greater and lesser saero sciatic ligaments; 3, 4. greater and lesser gaps or foramina, 13. Diagram showing the inclination and axis of the true pelvis, . 14. Diagram showing the axis of the parturient canal, .... 15. Interior of pelvis, showing the ischial planes, . . . . 16. Outlet of the female pelvis, ........ 17. Infantile pelvis, ........... 18. External organs, partially dissected (Kobelt), ..... 19. Showing the relative position of the pelvic organs, .... 20. Dissection of the lower half of the female mamma during the period o lactation (Luschka), ......... 21. Structure of a lobule of the mammary gland, ..... 22. Ultimate glandular vesicles of the mamma, ..... 23. Diagram showing relative position of the pelvic viscera (A. Farre), 24. Profile section of the uterus, ........ 25. Lateral section of the uterus, ........ 26 The os uteri, ........... 27. Pelvic organs in situ, viewed in the axis of the brim (after Schultze), 28. Anterior view of the uterus and its appendages (Quain), . 29. Posterior view of the uterus and its appendages (Quain), . 30. Diagrammatic view of the uterus and its appendages as seen from behind (Quain), . 31. Utricular glands of uterus (E. H. Weber), 32. Utricular gland of the uterus (Coste), ...... 33. Kelation of utricular glands to muscular tissue of uterus (Coste), 34. Termination of utricular glands on mucous surface of uterus (Coste), 35. Utricular orifices of uterus (Sharpey), ...... 36. Double vagina and uterus (after Busch), ...... 37. Bifid uterus, 38. Diagram showing the layers of the Graafian vesicle, and the contained ovum, . 39. Diagrammatic representation of the ovum, as it escapes from the Graafian vesicle, ............ 40. Development of Graafian vesicles in the sow, ..... 41. Ovary dissected, to show the structure of the Graafian vesicle at variou stages (Coste), 42. Structure of the corpus luteum (Coste), ..... 43. The corpus luteum of simple ovulation, ...... 44. Corpus luteum in the third month of pregnancy (Montgomery), PAGE 26 26 29 32 34 35 35 37 38 40 41 42 44 45 47 51 52 56 57 57 59 60 60 61 63 63 64 66 69 69 69 70 70 74 74 77 79 79 81 82 84 84 XX11 LIST OF ILLUSTRATIONS. FIG. 45. 46. 47. 48. 49, 52. 53. 54. 55. 56. 57. 58. 59. 60. 61. 62. 63. 64. 65. 66. 67. 68. 69. 70. 71. 72. 73. 74. 75. 76. 77. 78. 79. 80. 81. 82. 83. 84. 85. 86. 89. 90. 91. 92. 93. 94. 95. 96. 97. 98. 99. 100. 101. 102 103 104 105 106 107 108 109 Corpus luteum in the sixth month of pregnancy (Montgomery Corpus luteum at the period of delivery, ..... Tumefaction of the uterine mucous membrane during menstruation (after Coste), Spermatozoa and vesicles of evolution, .... 50, 51. Successive stages of the cleavage of the yolk, External surface of the ovum, showing the area germinativa Diagram showing the earliest formation of the embryo, . Diagram showing early stage of development, . Further development of the ovum, ..... Development in a more advanced stage, .... Completion of the amnion, and formation of the umbilical cord, Diagram showing Hunter's theory as to the formation of decidui Formation of decidua ; first stage;, ..... Formation of decidua completed, ..... Flap of decidua reflexa turned down, disclosing the ovum, Foetal surface of the placenta, ...... Maternal surface of the placenta, ..... Section of the placenta, ....... Foetal villi of the placenta, ...... Ultimate foetal villus, highly magnified, .... Ovum opened, and embryo partly dissected, . The same embryo, further dissected, .... Posterior view of branchial apparatus, etc., Posterior view of fcetal heart, ...... Dissection of an ovum in situ, about the fortieth day, Attitude of the foetus in utero, ...... Uterine cavity at the fifth month, ..... Upper surface of fcetal cranium, ..... Diameters of the fcetal cranium, ..... Circulatory apparatus in the foetus, ..... Diagram illustrating Groodsir's theory of foetal nutrition.. Fibre-cells of the unknpregnated and gravid uterus contrasted External muscular layer of uterus, ..... Internal muscular layer of uterus, ..... Degeneration of fibre-cells after delivery, Diagram showing development of uterine cavity (after Schultze) Areola, and secondary areola of pregnancy (seventh month), Cervix uteri (primiparse), twenty-fourth week, Cervix uteri (pluriparae), twenty-fourth week, . Cervix uteri (primiparse) thirtieth week, .... Cervix uteri (pluriparae), thirtieth week, .... Cervix uteri (primiparse), at full term, .... Cervix uteri (pluriparae), at full term, .... To calculate the duration of pregnancy (after Schultze), . Diagrammatic representation of partition in twin pregnancy (1st variety). Twin pregnancy (2d variet} 7 ), ...... Hydatidiform degeneration of ovum, .... Intra-uterine amputation and attempted reproduction, . Retroflexion of the womb about the 16th week (Schultze), Retroversion about the 12th week (Schultze), . . . Parturient canal completed by the obliteration of the os and Distension of the perineum (after Hunter), Alleged inversion of placenta in the third stage, Normal position of the placenta in the third stage, . Mode of digital examination, ...... Cranial planes as they engage in the brim, First cranial position, ....... Internal lateral surface of pelvis, ..... Lateral obliquity of the head advancing in the axis of the bri The head approaching the outlet. First position, . First position as seen from above (Schultze), . Diagrammatic representation of successive stages of the first position, Second cranial position, . . . . . . 85 LIST OF ILLUSTRATIONS, XX111 position, del of th FIG. 110. Second cranial position at the outlet, 111. Third cranial position, 112. Fronto-anterior termination of the third 113. Fourth cranial position, 114. Fourth cranial position at the outlet, 115. Diagram showing successive stages of rotation and facial position, . 116. First position of the breech, 117. Birth of the breech, .... 118. Birth of the shoulders, 119. Arm displaced upwards, . 120. Birth of the head 121. Fourth position of the breech, . 122. Artificial delivery of the head in breech 123. Transverse presentation — Dorso-anterior 124. Transverse presentation — Dorso-posterioi 125. Spontaneous expulsion. First stage, 126. Spontaneous expulsion. Second stage, 127. Spontaneous expulsion. Third stage, 128. Case of complicated presentation, 129. Braun's repositorium, 130. Cells of fatty and healthy decidua, . 131. Placental forceps, .... 132. Dr. Aveling's apparatus for transfusion, 133. Partial inversion (after Matthews Dunca 134. 135, 136. Successive stages of inversio ut 137. Thomas's method of reducing chronic Thomas), 138. Rachitic pelvis, 139. Malacosteon pelvis, . . 140. Isabel Redman's case, 141. Obliquely distorted pelvis, 142. Flattening of the sacrum, . 143. Funnel-shaped pelvis, 144. Exaggerated sacral curvature, . 145. Pelvic exostosis, .... 146. Baudelocque's calipers, and Coutouly's pi 147. Lumley Earle's pelvimeter, 148. Manual pelvimetry (Ramsbotham), . 149. Sketch of Chamberlen's forceps (Rigby), 150. Straight forceps for ordinary use, 151. Davis's forceps, ..... 152. Hodge's forceps, .... 153. Wallace's forceps, .... 154. Smith's forceps, .... 155. Elliot's forceps, .... 156. Robertson's forceps, .... 157. Simpson's forceps, .... 158. Introduction of the lower blade, 159. Introduction of the upper blade, 160. The forceps applied, .... 161. Forceps for application at the brim, . 162. Curve of abnormal promontory, 163. Introduction of long pelvic-curved force] 164 Diagram, showing various stages in the introduction of (lower blade), ....... 165. Introduction of the first bl^de in the dorsal position 166. Introduction of the second blade in the dorsal position 167. Instruments introduced and locked in dorsal position, 168. Long forceps applied, 169. Ziegler's forceps, 170. Radford's forceps, 171. The vectis, .... 172. Whalebone fillet, e uterus n th (after the long forceps first PAGE 300 304 307 308 308 318 328 329 330 331 331 333 340 344 344 347 347 348 354 364 371 384 417 419 419 429 445 446 446 447 448 448 448 451 453 455 455 462 465 466 467 468 469 470 470 471 477 478 478 483 489 491 492 493 494 495 496 498 498 501 503 XXIV LIST OF ILLUSTRATIONS. FIG. 173. The blunt hook, 174. The crotchet, .... 175. Podalic version, 176. Turning by the noose or fillet, . 177. Malacosteon pelvis, . 178. Bimanual version : first stage, . 179. Bimanual version: second stage, 180. Bimanual version : third stage, 181. Simpson's perforator, 182. Hodge's craniotomy forceps, 183. Guarded crotchet, 184. Craniotomy forceps, . 185. Osteotomist, .... 180. Meigs's craniotomy forceps, 187. Braun's eranioclast, . 188. Simpson's omphalotribe, 189. French cephalotribe, 190. Dr. Matthews Duncan's cephalotribe 191. Hysterotomy, .... 192 Barnes's uterine dilators, . 193. Uterine polypus as an obstacle to delivery 194. Ovarian tumor obstructing delivery, 195. Double-headed monster, . 196. Double monster, .... 197. Head represented descending directly in the axis of the brim, 198. Head represented descending in the position described by Naegele, 199. Lateral obliquity of the head advancing in the axis of the brim, 504 505 514 517 522 524 525 525 529 530 532 533 533 535 535 539 539 539 549 568 575 576 591 591 746 746 747 A SYSTEM OF MIDWIFERY, CHAPTEE I. IKTRODTJCTOBY. HISTORY OF MIDWIFERY — HIPPOCRATIC ERA — ARABIAN SCHOOL — AMBROISE PARE - — MATJRICEAU — ENGLISH MIDWIFERY — OBJECTIONS TO THE PRACTICE OF MID- WIFERY CONSIDERED— COMPARATIVE ANATOMY OF THE PELVIS — THE PELVIS AS A TUBE THROUGH WHICH THE PRODUCT OF CONCEPTION PASSES — PARTU- RITION IN THE PRIMATES: IN THE VARIOUS RACES — THE ERECT POSTURE THE MAIN CAUSE OF COMPARATIVE DIFFICULTY IN THE HUMAN SPECIES — THE HUMAN PELVIS A CURVED CANAL — SEPARATION OF PELVIC ARTICULATIONS DURING LABOR — MIDWIFERY DEFINED. The History of Midwifery is to the student of that art a subject not only interesting, but also in some degree instructive. To trace from their earliest development, whether in the crude ideas of ancient times, or in the hasty generalizations of an epoch not far distant from our own, the growth and maturity of theories which we now believe to be in accordance with the truth, is indeed in itself an attractive pursuit ; and the student has his reward in the thorough mastery he thus obtains over details, which can scarcely be eifected by the mere dogmatism of ordinary teaching. For various and evident reasons, however, the history of the obstetric art cannot be embraced fittingly within the limits which must be fixed for matter purely introductory to the study of a great practical subject. Not even in outline, then, will a consecutive history of midwifery be attempted ; but, as reference will in the sequel be not unfrequently made to the doctrines and practice of the past, a few sentences may here be devoted to the consideration of the midwifery of certain epochs, in view of the influence which these may be supposed to exercise on the practice of the present day. From the earliest records, more or less authentic, which seem to throw light upon the subject, it would appear that the practice of midwifery was in the first ages entirely in the hands of women. If we may judge, however, from the fact that a law was passed in Athens, at a very early period, by which women were absolutely prohibited from practicing 2 18 INTRODUCTORY. [CHAP. physic in any of its branches, we are entitled to assume that the art had not in the main prospered in their hands. It is in the Hippocratic writings that we find the first trace of a profound intellect and a truly scientific mind being applied to the observation of the phenomena of parturition. The works, indeed, on this subject, which are attributed to Hippocrates, are, for the most part, passed over as unauthentic by modern critics ; but there can at least be no doubt that they were written before Aristotle, at the latest, we may assume, about 400 B. C. The head, according to this authority, is the only natural presentation ; and when the child either lies across or presents by the feet, the woman cannot be delivered. Observe the effect of this aphorism. The head being thus assumed to be the only presentation in which the natural forces could effect delivery, it follows, as the natural corollary of this proposition, that one of the chief aims of operative midwifery must be to convert breech and footling as well as transverse presentations into presentations of the head. The contemplation of such a state of prac- tice is too horrible to dwell upon. His graphic illustration of the olive in the neck of the oil jar is familiar to all, and demonstrates to perfection that it can, in its long diameter, be easily passed through; but, he adds, if the long diameter of this oval body be thrown across, either the bottle will break or the olive will be crushed. It is strange, indeed almost incredible, that, having recognized the form of the foetus while in the womb, as his simile clearly shows, he should have failed to perceive that an oval body, be it olive or foetus, may pass by either end of its long diameter. Overlooking this fact, he established a rule of practice, which obtained in after ages, as there is every reason to believe, for a period little short of 2000 years, at what expense of maternal and foetal life it is impossible to compute. From this early period we must also date the operation of Craniotomy, for the per- formance of which quite intelligible rules are given. This error of Hippocrates was corrected by Celsus in the first century of the Christian era, and even, to some extent, at a much earlier date by Aristotle; but it is to the former that the credit in this matter is usually ascribed by the commentators, as his words are clear and free from ambiguity. Tins is manifest from the following sentence alone, extracted from the instructions given by him for the management of transverse cases : " Medici vero proposition est, ut eum manu dirigat, vel in caput, vel etiam in j)edes y si forte aliter compositus est." Some four or five hundred years later, a careful compilation of all that had been written up to that time on the subject of midwifery was made by iEtius. Among the untoward circumstances detailed as causes of difficult labor, he mentions a narrow pelvis, the presence of polypi, and obliquity in the position of the womb. He states, further, that an anchylosis of the ossa pubis at their point of junction is a fertile cause of difficult labor, by preventing the separation which would otherwise, he supposes, occur; and that distension of the rectum or bladder may constitute a mechanical impediment to delivery. He observes also, that difficult labor is due as well to a faulty condition of the child as to the maternal parts. If the child, or any of its parts, were unduly large, labor was presumed to be impeded by the fact that I.] MIDWIFERY AMONG THE ANCIENTS. 19 the motions and leaping of the ehild (supposed, even in comparatively modern times, to contribute greatly to its delivery) was thereby inter- fered with. Many other points of interest and of practical importance are referred to by him, one or two of which may be noticed. We have here, for example, in a chapter, " De Foetus Extractione ac Exsec- tione," which he takes from Philumenus, the first indication of the speculum vaginae, in an instrument which he recommends for the purpose of separating the external parts, in order to bring the cause of obstruction into view. We have also a perfect description of the crotchet (uncinus attractorius) ; and in his description of a method of delivery by the application of two crotchets — one to each side of the head — we cannot fail to observe that the mechanical principle of the midwifery forceps was not only then adopted in practice, but was thoroughly understood by the author, and brought him very near to the discovery of the forceps of modern times. And, finally, we have here the operation of turning in cases of difficult cranial presentation recommended, in terms which place it beyond a doubt that the pro- cedure indicated is in all respects identical with what of late years has been introduced in similar cases, as a novelty and an improvement in modern practice. The credit of the discovery and demonstration of the Fallopian tubes was claimed by Galen, but there is no doubt that they were described at a still earlier period than the epoch now in question by Rufus Ephesus, who lived in the reign of Trajan (circa A. D. 110). The last writer on this subject of the old Greek school was Paulus iEgineta, to whose works little originality can be attributed. The favor in which literature and the sciences were held by the Arabs evidently exercised a most beneficial influence in the development of the Arabian School of Midwifery. The name of Rhazes, a physician of Bagdad towards the end of the ninth century, is associated with the discovery of the fillet. About a hundred years later a very remarkable and voluminous series of works on midwifery and allied subjects was given to the world by Avicenna, a physician of Ispahan. His works consist for the most part in a confirmation of the leading views of the Greek school, and as they enjoyed an extraordinary popularity in Europe, as well as in Asia, it was by this channel mainly that the errors of the ancients were diffused throughout the world. The fundamental error of Hippocrates he adopts in a modified degree. All presentations, says he, save the head, are preternatural : the head ought, therefore, to be reduced, in all such cases, into the natural position, but, should this be impracticable, we may deliver by the feet. He recommends in certain cases the use of the fillet, which, when used for extraction, is to be fixed over the head ; and, should this fail, the forceps is to be applied to the head and extraction then attempted, while as a last resource only are the perforator and crotchet to be employed. 1 A reference to this passage makes it perfectly clear that the instrument alluded to is essentially the midwifery forceps ; while the fact that the author nowhere describes the instrument as a novelty warrants us in 1 See the chapter, " De regimene ejus, cujus partus tit difficilis causa magnitudi- nis foetus." 20 INTRODUCTORY. [CHAP. the belief that, about the tenth century, or possibly at an earlier period, the use of this important instrument was familiar to the Arabian physicians. In the works of a later writer, oi' the eleventh or twelfth century, 1 the forceps then used in midwifery is described and delineated. It is represented under two different forms, the misdach and the almisdaGh. In the Arab original in the Bodleian Library at Oxford to which Smellie refers in his learned introduction, the former of these 1 is described as straight and the latter as curved, but in the Latin version both are described as circular and full of teeth. From this period, until the discovery oi' the art of printing in the middle of the fifteenth century diffused a knowledge of the writings of the ancients throughout the civilized world, our art seems to have made but little progress. Indeed, wo may even say with truth, that after the decline of learning in the East, the art of midwifery, as practiced in Europe, was far interior to what obtained among the Arabians and even among the later Grecian writers. This we may easily understand if we reflect that Hippocrates was the text-book in the hands of all, and that his errors continued to influence the practice of midwifery until the dawn of science, after the dark ages of our art, dissipated in some measure the mists of ignorance and superstition. In 1518, Dr. Linacre, physician to Henry VI 11, obtained, through his interest with Cardinal Wolsey, letters-patent constituting a corporate body of regular physicians in London. This foundation of the Royal College oi' Physicians of England marks the period at which midwifery, for tin 1 first time in this country, was brought within the domain of science. It must be confessed, however, that the earliest efforts of English authors contributed but little to the advancement of the art, as founded upon true scientific principles. The first English work on the subject was a translation ofEucharius Rodian, by \h\ ftaynalde, under the title of " The Byrthe of Mankynde." 2 That this work was held in no little repute on the Continent is evident from the fact that it had been translated from the original High Hutch, not only into Latin, but also into Hutch, French, Spanish, and other languages. Ami yet, when we examine it critically, we find that, except as a literary curiosity, it scarcely merits our attention. Not only does he indorse the famous blunder of Hippocrates, by saying that we should turn the child to the natural position even when the feel present, but he boldly promulgates another error when he says that when the child presents in the natural way by the head, the face and foreparts of the foetus are towards the foreparts of the mother. In most other respects his views are but copies from the ancient writers. The same remark may be made with reference to the productions of his contemporaries, as we find doctrines which are essentially the same promulgated in the collections of mono- graphs, memoirs, and reproductions from ancient and modern sources, known as the " Gynseciorum Commentaria," a collection familiar to all who have studied this subject with care. A very superficial study of this compilation will suffice to show that even the more flagrant errors of the ancients were still systematically taught; and therefore arc we 1 Albueasis or Alsaharavius. 2 London, 15(55. I,] AMBROISE PARE. 21 bound to conclude that the Hippocratie aphorism of turning, by the head in breech presentation had, up to this period, been all but univer- sally adopted in European practice, even although that error had been to a great extent corrected by the later Greek and the Arabian writers. It is not, then, too much to assert, as we have done, that the blunder of Hippocrates, so frequently alluded to, was the rule of practice for little less than 2000 years after his death. In this collection, however, there is one work which we must mention with more respect — that of the illustrious Ambroise Pare" — of whom Smellie says no more than is his due when he terms him "the famous restorer and improver of midwifery." The revival of anatomical study under Vesalius, and the numerous dissections which had been made of pregnant women by him and by his follower Columbus, had already corrected many of the anatomical and physiological errors, which, being time-honored, were therefore considered to be respectable, and were generally admitted to be true. The belief in these doctrines being thus sapped by the logic of facts, the whole rotten superstructure began to crumble away, and from this epoch modern midwifery may be said to have had its origin. It required a mind of no ordinary power and energy to be the pioneer in this new path ; but it requires no critical analysis of the work of Pare to show that the great surgeon was a great master, and that scientific Midwifery as well as Surgery had at last found a fitting modern exponent. Pare advises turning by the feet in difficult cranial presentations; but if this cannot be done, he recom- mends craniotomy, or delivering by the 4 crotchet, — which instrument he directs us to fix, by the method of JEtius, in the orbit or mouth, or below the chin. He frankly confesses, that although he has carefully studied the position of the foetus in utero, he has been unable to come to a satisfactory conclusion as to what is to be considered the normal posi- tion ; while, as regards the causes of difficult labor, he dilates at some length, and on the whole with considerable accuracy. After pointing out with great clearness the serious nature of the impediment caused by cicatrices, the result of former midwifery accidents, he enumerates the various positions of the foetus which interfere with or prevent delivery, and concludes by noting the bad effects of a premature escape of the waters, and of uterine inertia. At this period, the Parisian school was undoubtedly the first in the world; and as all the leading surgeons there practiced midwifery, the practice as well as the theory of obstetrics became rapidly developed. Guillemeau, surgeon to the French king, and a pupil of Ambroise Pair, further developed the theories of his master; but the book which seems to have exercised the greatest influence was the remarkable one of Mauriccau, " Sur les Maladies des Femmes grosses, et de ccux qui sont accouchees." This author gives by far the best account which, up to his day, had appeared of the phenomena of labor as observed by the accoucheur. He criticizes with some asperity the views of Columbus, which, however, we find to be, at least as regards the position of the child in the womb, infinitely more correct than his own. The following are his conclusions on this point: Up to the seventh or eighth month, the child is situated in the centre of the womb, the head being towards 22 INTRODUCTOKY. [CHAP. the fundus and the face looking directly forwards. About this period an important change takes place in its position, which, if it happens sooner, is attended with danger. The weight of the head and upper part of the infant having now become relatively greater, it causes the child to turn forwards (/aire la culbute en devant), so that the face is now turned directly backwards to the promontory of the sacrum. This doctrine is simply an amplification of the views of Hippocrates on this point; and it must be admitted, even in the present day, that the greater relative frequency of breech and irregular presentations in cases of premature delivery, lends some apparent confirmation to the idea. He repudiates the idea formerly entertained, that the child, by its own instinctive or automatic movements, aided in any way in effecting its expulsion, and recognized not only the contractility of the uterine tissue, but also the supplementary expulsive force which is derived from the muscles of the abdominal walls, these acting, as he shows, with greater effect upon the rounded back and nates of the child than they could upon the head, did the head present. Mauriceau seems also to have some indistinct and inaccurate idea of the rotation which occurs in the pelvis; for, after stating that, in footling cases, it is necessary that the face in its descent should look backwards, he gives directions for turning the child during its descent, unless this has already taken place, so as to make the heels look directly forward. Any one who may wish to pursue this subject further will find ample and most interesting material in the works of Peu, Dionis, Deventer, La Motte, Puzos, Roederer, Levret, and others. In many of these, new errors are developed, such, for example, as the undue importance given to uterine obliquities by Deventer and his followers, who supposed them to be a frequent cause of tardy labor. The re- discovery of the midwifery forceps by the Chamberlens, about the middle of the seventeenth century, marks another and most important epoch ; but this will fall to be more particularly considered when we come to discuss the forceps and its uses. The interesting subject of the mechanism of parturition was inaugu- rated little more than a hundred years ago by Sir Fielding Ould, of Dublin, and this, too, is another important era in the history of mid- wifery. To trace the successive steps, from the faint glimmering of the truth which perplexed the shrewdness of Ould, and baffled the astuteness of Smellie, to the full development of the modern theory as it was laid before the scientific world in the celebrated essay of Naegele, would lead us upon ground which for the present we must avoid. In the sequel, and at the proper place, such of the historical facts as are essential to the comprehension of this subject will be briefly noted. 1 It seems, on first sight, a paradox that the practice of midwifery should involve, in the human species, the supervision of a function which is purely physiological, and should be claimed by its professors as an important branch of the healing art. So difficult, indeed, has this problem been of solution, that many, from Rodericus a Castro 1 For a critical analysis of this subject, see an essay by the author " On the Mechanism of Parturition." London, 18G4. I.] OBJECTIONS TO THE PRACTICE OF MIDWIFERY. 23 downwards, have asserted that the practice of the art was derogatory to professional dignity, and an unnecessary interference with a natural process. " Obstetriciam artem nee exercui nee exercere volo," wrote one of these ; and there is reason to believe that the words find an echo even now. We need scarcely pause to refute the former of the two objections. We presume we may hold it as proved that, from the very earliest times, women required and obtained assistance at the period of delivery. This assistance was afforded, as we have already seen, by persons of their own sex ; and that there is a fitness in this no one will gainsay. If we may judge, however, from the Athenian laws, we may assume that the practice of obstetrics did not prosper in the hands of women ; but it must be confessed that there is evidence enough in the works of Arsinoe and Cleopatra to prove that some of them, at least, were quite familiar with the doctrines and practice of their age. And it must be conceded further, in these days when women are knocking so loudly, and with such importunity, at the portals of professional recognition, that if the mantle of Mesdames La Chapelle and Boivin could be made to fall on the shoulders of their sisters of the present generation, female delicacy would be saved many a rude shock, and the cause of science would in no sense suffer. But what do they say who repudiate the general practice of the art? Women, they assert, should in their hour of need be attended by women, and only in the case of difficulty or danger should the male accoucheur be summoned. The answer to this simply is, that the assistance of the latter would, under such cireu instances, be of no value whatever, as without a knowledge of the healthy or normal standard, which can only be attained by the constant observation of the natural process, ignorance, not skill, would be called upon to act. To the full as rational would it be to ask him to compute distance or space who had no knowledge of the standards of lineal measurement or capacity. Certainly, in the present day, Men are required for the practice of midwifery, skilled in medicine and the applied sciences, and who do not think of their dignity, any more than of their ease and comfort, when their services are in this matter required. In regard to the other objection, we must, of course, admit that parturition is a physiological function. But, in the discharge of this function, there exist in the human species peculiar conditions which exercise, as compared with the lower animals, a special influence upon the progress and issue of labor. What these conditions are will be best understood by a reference to one or two points in comparative anatomy, which reveal certain analogies, the appreciation of which will clear away many difficulties, and a knowledge of which is, in point of fact, almost essential to the student of midwifery. At an early period of mammalian development, two rods or bars of cartilage may be observed passing, more or less obliquely, from the dorsal towards the ventral surface of the embryo near its caudal ex- tremity. 1 The two parts are separated at their dorsal extremity, where they embrace the vertebral column ; while in front, in most cases, they meet and form a symphysis. This is the primitive pelvis. As the 1 See Flower's " Osteology of the Mammalia." London, 1870. 24: INTRODUCTORY. [CHAP. process of development goes on, the cartilage of each side, widening to a great extent superiorly, ossifies from three centres, by the union of which the os innominatum is formed, the two lower segments — ischium and pubis — leaving a gap between them, the obturator or thyroid fora- men. If we except the Cetacea and Sirenia, in which the pelvis is almost rudimentary, these characteristics are common to the whole mammalia. The innominate bones are firmly united above to the sacral vertebra?, and usually below to each other at the symphysis ; and this union, firm as it is, is greatly strengthened by a double ligament- ous union of considerable strength between the sacral and caudal ver- tebra? on the one hand, and the ischia on the other. This is familiar to anatomists as the greater and lesser sacro-sciatic ligaments, which are sometimes replaced by bone — as in the sloth. The mammalian pelvis, then, by the union of the two innominate bones and the sacrum, forms, with some exceptions, a complete circle or girdle of bone; or, in other words, a short canal or tube, which has two outlets. Of these, the anterior is called the inlet or brim, which is marked more or less distinctly by a line which runs from the top of the symphysis pubis to the first sacral vertebra. The axis of this is — owing chiefly to the obliquity of the innominate bones — probably never parallel to the vertebral column, but diverges from it, more or less widely, according to what is termed the " inclination" of the brim. The outlet looks backwards or downwards according to the position of the animal, and is bounded in the dorso-ventral diameter by the caudal vertebra? on the one side, and the lower margin of the pubic symphysis on the other, and laterally by the great sacro-sciatic ligaments (or bones) and the converging borders of the ischia. As the planes of brim and outlet are never quite parallel, the axis of the pelvis is consequently more or less of a curve. A careful study of the form, and extent of development, in the various mammalian groups, shows clearly that, as in other parts of the skeleton, the ever-watchful provision by nature of means to an end is here strikingly exemplified. In the Cetacea, where there are no pelvic limbs, the pelvis is composed of two slender bones ununited inferiorly, the chief use of which seems to be to afford an attachment for the crura of the penis and clitoris. In the Armadillo, it is strong and powerful, to aid in the support of the exo-skeleton. In the Carnivora, the ilium and ischium are in a straight line and of nearly equal length, the pelvis being thus elongated and narrow. The symphysis is long, includes part of both pubis and ischium, and, in adult animals of this class, is usually closed by anchylosis. In the Seals, the pelvis is small and of a different form from the terrestrial Carnivora, the ilia being small, and the ischia and pubes long and slender. The symphysis is small and loose, admitting of being widely separated during parturition. In many of the Insectivora, the symphysis is absent, the bones being widely separated in the middle line. The pelvis of the mole, for example, is long and narrow, and its axis is nearly parallel with the vertebral column. The ischium, as well as the ilium, is united to the sacrum by anchylosis, and the brim is so narrow that, there being no union at the symphysis, the pelvic viscera lie external to the cavity, I.] COMPARATIVE ANATOMY OF PELVIS. 25 and parturition takes place beneath rather than through the pelvic canal. In the Rodentia the pubes and ischia are always largely developed, flat and diverging posteriorly, while the symphysis is long and usually osseous. The Guinea-pig is an exception, as here the union remains ligamentous, and admits of free opening during labor. In the order Ungulata, the Pecora or true ruminants are character- ized chiefly by the great development of the ischial tuberosity, forming a well-marked conical process which is diverted outwards on each side. The symphysis is long, and includes a considerable portion of the ischia, and large epiphyses are observed, forming the articulating surfaces. These parts ultimately become fused by anchylosis. In the Perisso- dactyla, the greater expansion of the ilia, as seen in a marked degree in the skeleton of the elephant, indicates, at first sight, an approach to the human type; but the narrowing of the pelvis at the level of the acetab- ula, and the comparatively small ischial and pubic portions, at once dispel the illusion. The Edentata have the pelvis more or less elongated, and the ischia largely developed. In almost all, the ischia are directly connected with the vertebral column by one or more osseous bridges, the single one in the sloth passing from the ischial spine, and thus representing the lesser sacro-sciatic ligament. This is carried to the greatest extent in the Armadillos, where a long unyielding tube is formed by the coalescence of the ilium and ischium on the one hand, and a consider- able number of sacral and pseudo-sacral vertebras on the other. In most of the Edentates, not only the sacro-iliac articulations, but also the symphysis pubis, are anchylosed. The Marsupiata and Monotremata are characterized by the great development of the ischia and pubes, and the development in the tendon of the external oblique muscle of the " marsupial" bones. The facts here cited will suffice to show that the pelvis, in the various groups into which the mammalia have been divided, is formed so as to suit the requirements of the individual. The mode of locomotion, be it leaping, running, or swimming, is revealed to the anatomist by an examination of the pelvic bones, and in every case it will be seen that the preponderance of ilium, ischium, or pubis, is due to the necessity which exists for certain mechanical arrangements, by which alone can the required muscular power be effectively applied to the bony levers. The pelvis is also an efficient support to the organs which are usually contained within it, and especially to those which are connected with the function of generation. The obstetrician, however, looks at the pelvis from a different point of view. In it he sees the osseous canal through which the product of conception must pass in the act of parturition. He sees in it also the protecting framework which shields the generative viscera from the effects of shock or injury. And, above all, he studies it as a structure which, if abnormal, may seriously obstruct the process of parturition. Let us look, then, for a moment, before quitting the subject, and from this standpoint, at the pelvis of the mammalia. Throughout the whole series, irrefragable evidence is afforded that the pelvis is' designed with a direct reference to the propagation of the species; and we find more- 26 INTRODUCTORY, [chap. Fig. 1. — Pelvis of the female guinea-pig. Fig. 2.— The same ; showing the separation of the bones during parturition. over, that, on the approach of labor, certain modifications of structure which then occur clearly prove that nature prepares the parts before- hand for the new function. Thus, in the Chevrotains, a group of little deerlike animals, formerly as- sociated with the musk-deer, the ischia in the males join the elongated sacrum by ossi fi ca- o ... tion of the sacro-sciatic liga- ments, but in the females the latter retain their normal ex- tensile texture. In the prolific guinea-pig, again, 1 the pelvis is long and laterally compressed, the passage being much nar- rower than the diameter of the head of the mature foetus. About three weeks before par- turition, the interpubic liga- ments become soft and extensile, sothatduring labor the innomi- nate bones separate from each other at the symphysis, the sacro-iliac joint thus becoming on each side a hinge. After this process, the symphysis quickly returns to its normal or former state, and in a few days presents only a little thickness and mobility. The young of the guinea-pig are far advanced at birth ; some of the deciduous teeth are shed in utero, and they run about and begin to eat soon after they see the light. In the cow, as the period of parturition approaches, a relaxation of the pelvic ligaments also occurs, but the process here is different. 2 The gradual upward curve and posterior projection of the ischia causes the well-marked dorsal projection of their tuberosities, which appear promi- nently on the rump, projecting on each side and above the coccygeal vertebra?. By this elevation of the ischia, the sacro-sciatic ligaments become a means of support to the pelvis, so that their action is, as compared with the corresponding structure in the human pelvis, as it were inverted. As the period of utero-gestation approaches its termina- tion, these ligaments, as well as those of the sacro-iliac joint, become relaxed to such an extent that the sacrum is observed to sink down- wards between the innominate bones, so that the ischial tuberosities become very prominent, and relatively elevated. The object of this is manifestly to render parturition easier. Did this, indeed, not occur, there can be little doubt that in the cow, as in some other ruminants, the difficulties of labor which occasionally arise would be of much more frequent occurrence. It is interesting to observe, as the probable cause of dystochia in those animals, that, owing to the greater curve of the 1 Owen. 2 Todd'* Pelvis. " Comparative Anatomy and Physiology of the Vertebrates." Cyclopaedia of Anatomy and Physiology." Supplement. 1859 Art. I.] COMPARATIVE ANATOMY OF PELVIS. 27 sacrum, the axis of the pelvis is necessarily more strongly curved than usual, and in this respect approximates to the human type. If we now turn to the Primates, we shall be able to show, by a com- parison of the human race with those of the mammalia which stand nearest to it in the scale, that the process of childbirth must be more difficult and more obnoxious to serious hindrance than in any — even the highest — of the other mammalia. In all the Simiina, the ilium is, as compared with man, much elongated. " Each os innominatum in the adult male gorilla," says Owen, " is one foot three inches in length, that of man being seven inches and a half; the breadth of the ilium is eight inches and a half, that of man being six inches." In the lower forms — as the baboons and monkeys — the ilium is even longer, relatively to the other bones of the pelvis, than is here described. The ilia are nearly in a straight line with the vertebral column, and the inferior rami of the ischia are directed almost horizontally inwards, entering into the formation of the pubic symphysis, which, in the ape tribe generally, may be more properly called the ischio-pubic sym- physis. The form of the cranium is the familiar and ready test, not only in distinguishing between man and the lower animals, but also between the various races of mankind. It is peculiarly interesting to us, however, to observe that a careful examination of the pelvis will also supply the same and as reliable information. The chief peculiari- ties of structure which are exhibited in the case of the highest of the Simiina have just been noticed. In addition, we observe that the depth both of the true and false pelvis is much greater than in the human race, that the sacrum is much narrower, especially in the chim- panzee, that the ischial spines are more closely approximated, and, above all, the antero-posterior measurements at the brim prevail greatly over the transverse. Were we to compare the highest Ape with the lowest Man, we would find the following broad points of distinction. In the Ape, a pelvis with the brim much more inclined, its antero-posterior exceeding its transverse measurement ; a bending of the pelvic brim at the ilio- pectineal eminence forming an angle of about 120°, called the Mo-pubic angle — a characteristic which, without exception, distinguishes the lower animals possessing pelves ; a marked elongation of the ilia ; and a parallelism of the symphysis with the vertebral axis. In Man, less inclination of the brim, and a constant preponderance of the transverse over the antero-posterior diameter ; the boundaries of the brim here alone in the animal kingdom on one plane ; great expansion of the ilia, as compared with their length ; and the symphysis forming an angle with the vertebral column. The import of this great gap in develop- ment is evident, and has its explanation in the adaptation of man alone of all created beings to the fully erect posture. The descriptive anatomy of the human pelvis will form the subject of another chapter. We shall here glance only at its special functions, in so far as they may be held to differ from those of the lower animals. In all the other mammals the habitual and only natural position or pos- ture of the animal is prone, — the dorsal surface being superior, the ventral inferior. In those in which pelvic limbs exist, the weight of the pos- 28 INTRODUCTORY. [CHAP. terior or pelvic portion of the trunk alone is transmitted through the pelvis to the cotyloid cavities, and thence transferred to the heads of the thigh-bones. In Man, the whole weight of the body above the pelvis is directly transmitted to it by the imposition of the last lumbar vertebra, on the base of the sacrum, from which again it is transferred, when the body is erect, to the femora, and in the sitting position, to the tuberosities of the ischia. To enter upon an analysis of the mechanical laws upon which this depends would be suitable to a work on animal physics, but we must here confine ourselves to such points only as are germain to our subject. The sacrum — which is relatively much broader and stronger in man than in any of the lower animals — is the part which receives the weight of the trunk, the centre of gravity being, according to Weber, 8.7 milli- metres above the sacro-lumbar joint, or just above the pelvic arch. It has been compared by Cruveilhier to a wedge, by others to the key- stone of an arch, and by Sir Charles Bell to the heel of a mast, — the base of the vertebral column being fixed so that the interval between the innominate bones may be looked upon as the step in which the vertebral mast is socketed and mortised. In any case we may consider the weight as being transmitted from the sacro-iliac joints in one of two directions: in the erect posture, it passes through the irregular, thick, and curved buttresses which are formed by this portion of the ilia directly to the cotyloid cavities; in the sitting posture it passes, on a posterior plane, from the same joints almost directly downwards to the tuberosities of the ischia. The sacrum is thus described as forming the common culminating point of two arches — viz., the cotylo-saeral or standing arch, and the ischio-sacral or sitting arch. The extremities of these arches are prevented from starting outwards, not by abutments as in the ordinary architectural arch, but by connecting links or ties, which are represented in the cotylo-saeral arch by the horizontal rami of the pubes, and in the ischio-sacral by the united isehio-pubic rami. This complicated arch acts also by preventing inward pressure, in the erect posture, by the head of the femur; while shock is in a great measure obviated by the oblique manner in which the sacrum is placed — the sacro-sciatic ligaments preventing the movements of the coccyx upwards and backwards, while the ilio-lumbar ligaments prevent the correspond- ing motion of the base of the sacrum downwards and forwards. 1 The expanded external surfaces of the ilia give attachment to the mass of the glutei muscles, more powerful, for obvious reasons, in man than in any other animal. But the pelvis has, in addition to the elaborate mechanical functions above shortly alluded to, a new and special function thrown upon it in Man. This is the support of the pelvic viscera, including the organs of generation. These latter being larger and heavier in the female, and, in view also, no doubt, of the requirements of the pregnant state, nature here makes special provision for their accommodation, in the greater capacity and modified form to which we shall afterwards advert. 1 Dr. Matthews Duncan, in bis " Researches on Obstetrics'' (p. 55), shows more correctly, that the weight is transferred from the sacrum to the cotyloid cavity, not directly, hut indirectly through the agency ot the posterior ilio sacral ligaments. I-] COMPARATIVE ANATOMY OF PELVIS, 29 Fig. 3. Diagram showing the direction in which the uterine contents grav- itate in the Mammalia generally. In the lower animals, the abdominal viscera, and, to some extent, also, the pelvic viscera, are supported by the lower abdominal wall. The contents of the pregnant uterus, therefore, gravitate downwards in the direction of the arrow in the figure, and, under no circumstances, does the weight of the uterine contents press into the cavity of the pelvis. Even in the Simiina, where the erect posture is to some extent assumed, the greater inclination of the pelvic brim prevents the gravitation of the uterus and its contents into the true pelvis. In a pregnant woman, on the other hand, not only are the pelvic viscera proper supported by the structures which form the floor of the pelvis, but some support is indi- rectly afforded to the abdominal viscera under certain circumstances. In the preg- nant state, the uterus and its contents gravi- tate to a considerable extent downwards and backwards in the axis of the brim. The necessity which thus exists for efficient pelvic support to these parts has not been overlooked. Were the pelvis a simple tube, with the inlet looking upwards, and the outlet downwards, it is obvious that no efficient sup- port could be afforded. But the tube, far from being straight, is in a woman strongly curved — so strongly indeed, that a line drawn so as to represent the axis of the brim and the long axis of the uterus (which we may here assume to be identical) will not fall within the plane of the outlet at all, but behind it, somewhere about the centre of the coccyx. By this curve in the pelvic axis, the lower part of the sacrum, the coccyx, the sacro-sciatic ligaments, the levatores ani and coccygei muscles, and the fascial and soft structures form a firm floor, by which, in a normal and healthy condition of the parts, perfect support is given to the structures of which we have spoken. But this manifest advan- tage is obtained at the price of increased difficulty in the act of parturi- tion. This difficulty is, no doubt, to a very great extent, compensated for by the development of the subpubic arch, a peculiarity of the human species which is but imperfectly developed in the lower animals. Without this, indeed, and that shortness of the symphysis in women which admits of its widest development, labor would be always diffi- cult and often impossible. The function of the pelvis being thus in every case a complicated one, is so in the human female in an especial degree. The unyielding nature of the structure, essential to the effectual support of the trunk, and the curving of its cavity for the reasons above stated-, render child- bearing in this instance exceptionably liable to dangers of various kinds, and thence arises the necessity for that thorough training which can alone engender confidence and develop skill. The comparative facility with which parturition is effected in the lower races of the human species has also been used as an argument against the practice of midwifery. In reference to this objection, on 30 INTRODUCTORY. [CHAP. which we need not dwell, there can be little doubt that the effect, in certain classes of society, of modern and luxurious habits, exercises no inconsiderable influence upon the physiological phenomena of parturi- tion. As regards the difference between the races, many very interest- ing facts have been revealed by the researches of Vrolik, Weber, and others, but there is still in this direction a wide field for original investigation. The facts which already have been disclosed point to the important conclusion that there subsists in the various races a remarkable coincidence between the prevailing form of the skull and the diameters of the pelvic brim, and that, consequently, the adaptation of the foetal skull to the pelvic passage during labor must be greatly facilitated. Weber's conclusions, drawn from the observation and measurements of a considerable number of specimens, are, that we may admit, as the general rule, subject however to numerous exceptions, that the oval shape is most common in Europeans, the round shape in the American aborigines, the square shape in the Asiatic or Mongolian type, and the oblong in the Negro races. As regards the assumed facility of labor in those races, there is every reason to believe that this has been greatly exaggerated, and that cases of dystochia, though comparatively rare, are yet not unfrequent. If the pelvis were the same in size and proportion in them as in Europeans, the inferior cranial development would afford an obvious explanation of the alleged fact of habitually easy labors. So far, however, from this being the case, we have just seen that the form of the pelvis corresponds to the shape of the head. An examination of Negro, Bushman, and other pelves, shows in many instances a remarkable degradation of type, such as a vertical direction of the ilia, and their elevation at the posterior-superior spines, narrow- ness of the sacrum, and acuteness of the subpubic angle. An occa- sional peculiarity in some of the lower races, and one which appears even more to approach to the ape type, is the preponderance of the con- jugate over the transverse diameter of the brim. But they who have asserted that the lower races referred to simulate in this respect apes rather than Europeans have gone too far, as is clearly proved by the measurements given in Wood's admirable article on the Pelvis in Todd's Cyclopaedia, already quoted. From this it appears, that while the transverse may, in the higher Simiina, measure less than the conjugate diameter by one and a half to two inches, the difference in cases of oblong pelvis in negroes is merely fractional, and that the type is in every case far more closely allied to the European than to the Simian, where the conformation of the pelvis is such, even in the highest forms, that its marked peculiarities are appreciated at a glance. Whether the pelvic articulations in women are, or are not, divaricable during parturition, is a question obviously of great practical importance to the accoucheur. Involving, indeed, as it does, practical considera- tions, this is a subject, the study of which might here be considered premature. But, in view of the facts which have just been stated in relation to the comparative anatomy of the pelvis, this vexed question may, we believe, be noticed with more advantage at this stage than at any other. In so far as a study of the physiological phenomena of labor in the lower animals can throw light upon the subject, we have I.] MOBILITY OF PELVIC ARTICULATIONS. 31 already seen that separation may take place to a very considerable extent at the symphysis, as in the guinea-pig, or at the sacroiliac joint, as in the cow. So far, then, analogy points to the possibility of such a separation. Besides, anchylosis of either one joint or the other, com- mon as it is in the lower animals, is known to be, in the human species, an extremely rare occurrence. Actual observation, again, by men of such undoubted authority, among many others, as Par6, Levret, and Smellie, has proved, beyond all possibility of doubt, that in women who have died during the par- turient period, separation of the bones, now at the symphysis and again at the sacro-iliac joints, has been seen and recorded. Few practitioners of extended experience have failed to observe that women occasionally complain, it may be either before or after labor, of pain in the neigh- borhood of these joints, difficulty or inconvenience in walking, and, more rarely, a grating or crepitant feeling, arising obviously from an unwonted motion of the articulating surfaces upon each other; from which we may conclude that separation may, to some extent at least, occur. Cases such as have been detailed by Soemmerring — where the bones at the sacro-iliac joint have been found separated to the extent of an inch — have been supposed to be the result of disease and deposit of pus. Admitting, then, that some separation does occasionally occur, are we to assume that this is to be held as morbid or abnormal, or admitted as one of the essential physiological phenomena of human parturition ? It is, we suppose, now universally believed that, during the last months of pregnancy, the cartilaginous and other structures forming these joints, to be hereafter described, become softened, as if by serous infiltration. The synovial membranes, indistinct before, now become capable of demonstration; and, more important, perhaps, than all, the tissues become thickened, while the ligaments of the joints are relaxed. The effect of such thickening must, of necessity, be, like ivy roots in a wall, to force the bones asunder and, consequently, to increase the pelvic diameters. If, however, there is, as has been asserted, a yielding much more extensive than this, such motion may be assumed to occur in one of two ways; either by a separation of the pubes, involving a hinge motion at the sacro-iliac joint, as in guinea-pigs, or by a movement of the sacrum between the ossa innominata, involving a hinge motion of the symphysis, as in the cow. As regards the first of these, a careful examination of the circumstances under which it may occur, would seem to indicate that a separation of the pubic bones to the extent even of an inch would add very little to the diameters of the brim, and would contribute least of all to the smallest or conjugate diameter. The analogy which the frequent yielding of the symphysis seems to reveal, gave rise, about the end of the last century, to an operation consisting in the artificial section of the symphysis in cases of obstruc- tion at the brim — a mode of procedure which Dr. Matthews Duncan seems to think has been in these days too completely consigned to oblivion. The other method in which the pelvic capacity may be increased by a movement of these joints, is by the motion of the sacrum between the ossa innominata, somewhat as it has been shown to occur in the 32 INTRODUCTORY. [CHAP. cow. 1 From what has already been said, it may be inferred, that to compare the sacrum either to a wedge or a keystone is very far from accurate. We have seen that this bone, besides its union with the sacrum by means of intervening cartilage, is maintained in its position by the ilio-lumbar and sacro-sciatic ligaments — the former preventing, or rather strictly limiting, along with other forces, the downward and forward movement of the promontory ; while the latter limits, in like manner, the upward and backward motion of the coccyx. Now, these ligaments share in the general relaxation of the pelvic structures towards the end of gestation ; and thereby we may assume, that the movement or oscillation on its transverse axis, of which the sacrum is capable, and which is said by Zaglas to be about a line in the unimpregnated con- dition, is, in the last months of pregnancy, considerably increased. The manner in which this oscillation of the sacrum takes place in different positions of the woman is clearly shown by Zaglas. " In the erect position, the promontory of the sacrum is not in the position of greatest projection into the brim of the pelvis, but the reverse; and, conse- quently, the apex is in its forward fig. 4. position, diminishing the outlet and relaxing the sacro-sciatic ligaments. When the body is bent forward, on the other hand, the base of the sac- rum is protruded into the brim, the apex is tilted upwards, the sacro- sciatic ligaments put on the stretch, and the outlet of the pelvis conse- quently enlarged. These move- ments take place, ordinarily, both in man and woman, in defecation, etc., but in her they are of greatest interest and importance in the func- tion of parturition. 7 ' 2 The backward motion of the coccyx has also the effect of producing lateral widening of the pelvis, by bringing a wider part of the base of the sacrum between the ilia. This, of course, supposes some gliding motion in the sacro- iliac articulation, or, at least, yielding of the parts. The experiments of MM. Giraud and Ansiaux seem to show that, in contracted pelves, the movements take place to an even greater extent, as if nature were doing her utmost to obviate the disastrous effects of pelvic deformity. Dr. Matthews Duncan, in his admirable essay on this subject, points out, with great clearness, the very remarkable manner in which these alterations correspond with the phenomena of the progress of the child in parturition. In the first stage of labor, for example, when the head is passing through the brim, the woman prefers the standing, sitting, or reclining posture, in which the brim of the pelvis is, as we have seen, kept open at the expense of the outlet (see Fig. 4) ; but in the second stage she bends her body forwards, draws up her legs, and calls 1 Barlow. Monthlj* Journal of Medical Science, January, 1854 2 Matthews Duncan. Op. cit, p. 142. Diagram showing the oscillatory movement referred to. (Matthews Duncan.) II.] THE PELVIS. 33 into action the abdominal muscles, which act by tilting up the sym- physis ; in a word, her posture and voluntary efforts are now precisely those which may most effectively increase the conjugate diameter of the outlet by tilting back the coccyx. To the motion of the sacro- coccygeal joint, which is universally admitted, we need not at present specially advert. From these and other facts disclosed up to the present time we con- clude: 1st. That, in the last months of pregnancy, a marked relaxa- tion and softening of the pelvic articulations takes place. 2d. That, as the result of this modification in structure, an in- creased, though limited, mobility is permitted, which tends to facilitate labor. 3d. That in addition to the movement of the sacrum on its transverse axis, as above noted (and which may be considered as peculiar to the human species), the manner in which the joints yield is probably very similar to what obtains in the case of the cow. The sacrum acts in this case as a wedge separating the ossa innominata and causing the symphysis to open with a hinge motion, while, during the violent efforts of labor, the whole sacrum may probably be driven backwards to a trifling extent. Separation of the bones at the symphysis is occasionally observed, but this is probably the exception, while the other is the rule. The development of the synovial membranes seems, when taken along with the above facts, to warrant the conclusion arrived at by Lenoir, " that the articulations of the pelvis proper should not be considered as amphiarthroses, but as arthroses" The word " Midwifery," it is proper here to state, is employed in this work in the more extended sense in which it is used by Rigby and other English authors, and not in the limited sense which is implied by the French accouchement, and the German Geburtshiilfe. It signifies, therefore, that Science and Art, which has for its object the manage- ment of woman and her offspring during Pregnancy, Labor, and the Puerperal State. CHAPTER II. THE PELVIS. OS INNOMINATUM : SACRUM: COCCYX — THE PELVIS AS A WHOLE: "TRUE 7 ' AND "FALSE" — DIFFERENCE BETWEEN MALE AND FEMALE PELVIS: AT BRIM; IN cavity; and at outlet — PELVIC articulations: (a) PELVI-LUMBAR ; (b) SACRO-COCCYGEAL ; (c) SACRO-ILIAC ; (d) SYMPHYSIS PUBIS ; (e) OBTURATOR LIGAMENTS; (/) SACRO-SCIATIC LIGAMENTS — INCLINATION OF PELVIS — AXIS OF THE TRUE PELVIS — BRIM OR INLET — CAVITY — OUTLET— PEL VTC DIAM- ETERS — PELVIC ANGLES DEVELOPMENT OF PELVIS CERTAIN SOFT PARTS CONNECTED WITH PELVIS; OBTURATOR INTERNUS AND PYRIFORMIS MUSCLES; " FLOOR " OF PELVIS. The Pelvis, as has already been observed, is composed in Man, as in almost all the other Mammalia, of three parts : 1st, an os innomina- 3 34 THE PELVIS. [CHAP. Fig. 5. External surface of right os innominatum. turn, formed by the union of three principal pieces, the ilium, ischium, and pubis, and some other epiphysial parts, the complete fusion of which into one mass is only complete about the twentieth year ; 2d, the sacrum ; and 3d, the coccyx. The Os Innominatum on its external surface exhibits the remarkable ex- pansion of the ilium which constitutes one of the distinguishing features of the human race. This large surface serves to give attachment to the pow- erful glutei muscles. Its superior margin is called the crest of the ilium ; the projections at 1 and 2 the ante- rior, and those at 3 and 4 the poste- rior spinous processes. The acetabu- lum, a deep cavity for the reception of the thigh-bone, also called the coty- loid cavity, with its synovial depres- sion and pit for the reception of the round ligament, is shown in the cen- tre of the figure. 5 marks the pecti- neal or ilio-pectineal eminence, a point of some importance in midwifery; and the other parts indicated are, 6, the symphysis pubis ; 7, the tuberosity of the ischium ; 8, the thyroid or obturator foramen ; and 9, the spine of the ischium, which divides the great posterior gap into the greater and lesser sciatic notches. In the view of the internal surface of the innominate bone, the figures 1 to 9 indicate the same parts as in the preceding cut ; 10 is the iliac fossa ; 11, the ilio-pectineal line or brim of the true pelvis ; 12, auricu- lar cartilaginous surface of the sacro-iliac joint; 13, rough tubercu- lated surface for the posterior sacro-iliac ligaments ; 14, spinous process of the pubis, terminating the crest of the pubis and the ilio-pectineal line. The relative position of the rami of the ischium and pubis, and other points familiar to the anatomist, are clearly shown in both figures. The Sacrum is an irregular wedge-shaped or triangular bone, formed by the fusion of five vertebra?, and is more or less curved, with the con- cavity forwards, the base of the triangle being upwards. It is placed below the last lumbar vertebra, above the coccyx, and between the ossa innominata, and forms the upper and back part of the pelvis. It is in man stronger, and relatively larger, than in any other animal, this characteristic being specially marked in the female. The external or posterior surface is convex and rough, and there are four, and some- times five, processes placed below each other in the median line, repre- senting the spines of the original vertebra?. On either side, four foramina are observed, through which the posterior sacral nerves pass from the cauda equina, which is contained in a longitudinal canal, the continuation of that of the vertebral column. Below the last spinous process, is a triangular opening, which is the termination of the verte- bral canal, and of which the lateral margins terminate in a pair of II.] BONES OF PELVIS, 35 tubercles. These, which project downwards, and articulate with the cornua of the coccyx, are known as the sacral cornua. A row of tuber- cles is seen on the inside, and another on the outside of the foramina, — corresponding to the articulating and transverse processes of the vertebrae. The pelvic or anterior surface (Fig. 7) is concave from above down- wards, and slightly so from side to side, and is much smoother than the posterior. Four foramina, larger than those above described, are Fig. 7. Internal suiface of the same bone. Sacrum and coccyx — internal surface. provided for the transit of the anterior sacral nerves ; and between the foramina are four ridges, indicating the boundaries of the original vertebral constituents of the bone. Laterally, there is presented anteriorly an uneven surface of consider- able size, covered in the recent state with cartilage, and corresponding to the iliac articulating surface shown at 12, Fig. 6. This is called from its shape the auricular surface ; and behind it there is an extremely rough and uneven surface for the attachment of the posterior sacro-iliac ligaments. Below and behind this, the irregular surface gives attach- ment to the sacro-sciatic ligaments. The oval surface of the sacrum, which, looking upwards and for- wards, represents the base of the bone, is articulated, through the medium of the interarticular disk, with the last lumbar vertebra; while its narrow inferior extremity, transversely oval, is jointed with the superior surface of the coccyx. The Coccyx , the rudiment of the caudal vertebrae, generally consists of four small vertebral pieces tapering downwards to a point. It derives its name from a fancied resemblance to a cuckoo's beak, and is placed so as to continue, anteriorly and posteriorly, the curve of the sacrum. An oval surface (covered with cartilage and furnished with a synovial membrane) articulates with the apex of the sacrum ; and this union is strengthened by two small processes which project upwards to- 36 THE PELVIS. [CHAP. meet the cornua of the sacrum. Not only is the sacro-coccygeal joint a perfect hinge, but the various bones of which the coccyx is composed also admit of some motion in early life the one upon the other. In adult life these bones are generally anchylosed, and the sacro-coccygeal joint is, in males generally, and in females occasionally, lost, so that the sacrum and coccyx are firmly joined together. The superior mobility of the coccyx in women is universally admit- ted as an important mechanical advantage in the process of parturition, the aiitero-posterior diameter of the outlet being by this resiliency increased, under ordinary circumstances, by an inch or even more. Usually, during the childbearing period, the parts are in the condition of complete mobility as regards the sacro-coccygeal joint, and yielding also between the first and second bone of the coccyx, while the last three bones are united. 1 In this respect, however, great irregularities exist, and sometimes, even in women who are still young, complete anchylosis is observed. The result of this is, of course, a very consid- erable impediment to delivery, and many cases are recorded where, during the use of instruments, or even in the course of ordinary labor, a fracture of the bones thus anchylosed has occurred. Premature fusion of this articulation, and malformation of the coccyx are conditions by no means very uncommon. The usual form assumed in the latter case is projection forwards, encroaching upon the conjugate diameter of the outlet; but a projection of the coccyx backwards has also been noticed by the writer and others, a condition which is interesting as an ana- tomical peculiarity, but is rather favorable than obstructive to the course of natural labor. In cases of fracture, care must be taken, dur- ing the reparative process, to prevent union in such a position as to constitute a possible impediment to delivery in subsequent labors. The Pelvis as a Whole. — The Pelvis is thus formed by the union of several pieces, the articulations or points of junction being, in front, the symphysis pubis, and, behind, the sacro-iliac and sacro-eoccygeal joints. These articulations are greatly strengthened by certain liga- mentous structures which will be presently described. It is divided into two parts by a line, the various parts of which are in man alone on the same plane. This, known as the ilio-pectineal line, marking the brim or inlet of the pelvis, runs on each side from the symphysis pubis outwards, upwards, and inwards, forming an irregu- larly oval constriction of the osseous canal. Various points in the course of this line, which divides the superior or false from the inferior or true pelvis, are of special interest to the obstetrician. In the middle line anteriorly is the symphysis pubis. Diverging right and left from this point, are the pubic crests, terminating in the pubic spines. The finger, on being passed around, next touches the pectineal or ilio-pec- tineal eminence, then the ilio-sacral articulation, and finally the pro- jection known as the promontory of the sacrum. This last point is of paramount importance, as the degree of projection which forms the 1 Cazcaux assorts that the sacro-coccygeal articulation ossifies generally before the first and second bones become united. If this is correct, the mobility in these cases must manifestly be impaired. II.] MALE AND FEMALE PELVIS CONTRASTED. 37 Fig promontory exercises a most important influence on the progress of a case of labor. The true pelvis, then, includes the whole of that part of the structure which is below the brim as far as the outlet, the space comprised be- tween the two being the cavity. Each of these parts requires careful and separate consideration ; but, before passing to this part of the sub- ject, it is advisable that the striking contrast between the male and female pelvis, having an obvious relation to the function of parturition, should be noticed. The female differs from the male pelvis, in the first place, by the comparative slenderness of the bones, as is well seen in the rami of the ischium and pubis, and also by the greater smoothness of the surfaces to which muscles are attached. The chief points of distinction, as viewed from before, are well shown in Figs. 8 and 9, in both of which the numbers 1 and 2 represent the extremi- ties of the widest trans- verse diameter of the upper or false pelvis ; 3 and 4 are the acetab- ula, right and left ; 5, 5, the thyroid or obtu- rator foramina ; and 6, the subpubic angle or arch. The differences exhibited are those which exist between an ordinary male and female pelvis in mid- dle age : in neither case is there anything ex- aggerated or unusual. The greater distance in Fig. 9 between the ace- tabula, the wider and shallower true pelvis, the triangular form of the obturator foramen, the greater width be- tween the tuberosities of the ischia, and the greater span of the subpubic arch, are the chief points which at a glance show it to be a female pelvis. The last- mentioned point of distinction is very characteristic in well-formed pelves, the angle in males being no more than 75° to 80°, while in the female it reaches from 90° to 100°. Viewed from above and in front, at right angles to the brim of the Male and female pelves contrasted, (Quain.) 38 THE PELVIS. [CHAP. Fig. 10. Fig. 11. true pelvis, the contrast is scarcely less marked. In the lower of the two figures showing this view, the further peculiarities of the female pelvis are evidenced by the greater expansion of the ilia, the minor degree of projection of the promontory of the sacrum, and the mark- ed general increase in the diameters. In the cavity, the most note- worthy feature of the female pelvis is the diminution in the per- pendicular depth, the symphysis being in the male nearly double the depth, while the sac- rum is shorter as well as broader, and placed so as to offer a more ample concavity. It will also be noticed, in looking downwards and backwards, as is shown in Figs. 10 and 11, that three projec- tions are seen — poste- riorly the sacrum and coccyx, and on either side the converging ischial planes, culmi- nating in the ischial spines. These projec- tions, encroaching, as they manifestly do, on certain measurements of the lower parts of the pelvis, have, as will be explained afterwards, a very important bearing upon the mechanical laws which govern the process of parturition. If, again, we look at the bony outlet, we find here also three projec- tions, posteriorly the sacrum and coccyx, and at the sides the ischial tuberosities. Between the latter is the subpubic angle, while between them and the sacrum on each side is the irregular sacro-sciatic gap, partly closed, as we shall see presently, by powerful ligamentous struc- tures, and much more spacious in the female than in the male. 1 These, the main features which enable us to distinguish between the male and i The greater expansion of the ilia, and divergence of the cotyloid cavities, give the chief peculiarities to the female figure, in regard to which the ancient Greek sculptors are probably not far from the truth in representing their ideal of female beauty as measuring a third more across the hips than the shoulders, while these measurements are reversed in the case of Apollo. The same peculiarity occasions the peculiar swinging gait, which is the more marked in a woman the broader the pelvis is in proportion to her height. Male and female pelves contrasted, as viewed in the axis of the brim. (Quain.) II.] PELVIC ARTICULATIONS. 39 female pelvis, having now been noticed, we shall advert in future to the female pelvis alone. The ligaments and articulations which bind the various parts of the pelvis together may now be briefly noticed. a. Pelvi-lumbar Articulation. — In addition to the intervertebral disk, and the ligaments which are strictly analogous to those existing between the vertebras above, attention must here be paid to the sacro-vertebral and ilio-lumbar ligaments. The former passes, expanding as it descends, obliquely from the tip of the transverse process of the last lumbar ver- tebra, to the depressed lateral part of the base of the sacrum ; the latter horizontally between the tip of the transverse process of the last lumbar vertebra and the posterior margin of the iliac fossa, where it somewhat expands. b. Sacvo- coccygeal Articulation. — An anterior and posterior ligament, and an intervertebral disk, are here found as in the more perfect verte- bras. There is observed besides in women, and in a lesser degree in the male sex, a synovial membrane, described by Cruveilhier, and which converts this into a perfect hinge joint, the structure and mobility of which become, as has already been mentioned, much more obvious in the latter stage of pregnancy. c. Sacro-iliac Articulation. — The bones are here joined by a twofold union ; in the first place, by the cartilaginous auricular surfaces which are seen anteriorly when the parts are forced asunder, and from which the name synchondrosis is often given to the joint. Generally, these surfaces are closely united ; but in pregnant women, and, probably, under certain other circumstances, an indistinct synovial cavity may be demonstrated, admitting, as there is every reason to believe, of a certain amount of motion. This union is greatly strengthened by the posterior sacro-iliac ligaments, consisting of strong irregular bands of fibres which pass from the overhanging portion of the ilium to the contiguous rugged projections on the lateral surface of the sacrum. One of these bands, extending downwards from the posterior superior iliac spine to the third or fourth piece of the sacrum, in a direction different from the other fibres, is known under the name of the oblique sacro-iliac liga- ment. An anterior sacro-iliac ligament is also described, but is of little anatomical importance. d. The Symphysis Pubis. — This joint is, like the previous one, also effected by fibro-cartilaginous plates and ligaments. The two cartilages are thicker in front where they come into contact with each other, and thinner posteriorly, so as to leave a space which is, as in the other joints just described, lined by a synovial membrane. During preg- nancy, an effect is produced upon this joint precisely similar to what has been stated to occur in the sacro-iliac joints, but it is in this case even more marked. The articulation is materially strengthened by the ligaments which surround it, named respectively posterior, superior, anterior, and inferior pubic ligaments. Of these, the posterior is a layer of fibres of little strength ; the superior is connected with a band of fibres which arises from the spine of the pubis, and conceals the irregu- larities of the crest of the same bone ; the anterior is a layer of irregular fibres passing across from one side to the other, and crossing obliquely 40 THE PELVIS. [CHAP. Fig. 12. the corresponding fibres from the other side, and the inferior, triangu- lar, or subpubic ligament is so thick, and so formed by its attachments to the rami of the pubic bones as to give smoothness and roundness to the subpubic angle, and thereby to facilitate the passage of the foetus. e. The Obturator Ligaments. — These structures, which are more cor- rectly described as membranes, close almost entirely the obturator foramina, giving attachment externally and internally to the obturator muscles, and leaving only a small aperture in its upper and outer part, which serves to transmit the obturator vessels and nerve. /. Sacro-sciatic Ligaments. — These are two in number, longer in the female than in the male, and become, to some extent, relaxed during labor. The posterior, or great sacro-sciatic ligament (Fig. 12, 1), which is placed in the inferior and posterior part of the pelvis, is broad and triangular in shape, and extends from the inner surface of the ischial tuberosity, which is the apex of the triangle, to the side of the coccyx and sacrum, as far as the posterior inferior spine of the ilium. This extensive attachment constitutes the base. The fibres of the apex expand, so as to send a falciform process up- wards and forwards, along the margin of the ischial ramus, to join the fibres of the obturator fascia. 2 is the ante- rior or small sacro-sciatic ligament, which is both shorter and thinner than the other, and is also of a some- what triangular shape. Its fibres are directed forwards and outwards ; the fibres constituting its base are blended with those of the larger ligament ; and its apex is attached to the spine of the ischium. By means of these struc- tures, which are ossified in some of the lower animals, it will be observed that the sacro-sciatic notches are converted into foramina, great and small sacro-sciatic ; 3 and 4. Through the former of these, the pyri- form muscle, the great sciatic nerve, and the ischiatic vessels and nerves pass, while the latter admits of the exit from the pelvis of the obturator interims muscle and the pubic vessels and nerve. The obstetrician may look upon these ligaments as discharging a double function. They act, as has already been mentioned, by pre- venting the displacement of the apex of the sacrum upwards and back- wards, — an accident wdiich, without their aid, the very oblique position of that bone would in the erect posture be likely to engender; and therefore, in this sense, they strengthen the sacro-iliac articulation. But, in addition to this, they close in, in some measure, the large irregular opening which constitutes the outlet of the pelvis ; forming, at the same time, the framework of those soft structures which consti- Internal surface of female pelvis, showing — 1, 2, greater and lesser sacro-seiatic liga- ments; 3, 4, greater and lesser gaps or for- amina. II.] INCLINATION OF THE PELVIS. 41 Fig. 13. tute the floor of the pelvis — which exercise a very important influence on the progress of labor, and which act also by affording an efficient and elastic support to organs which would otherwise be liable to fre- quent displacement downwards. In addition to the ligaments above described, there are others, some of them — as those of the hip-joint — of great importance; but as they have no special obstetrical interest, their description may here well be omitted. Inclination of the Pelvis. — If we place the articulated pelvis on a table, so as to bring the tip of the coccyx and the ischial tuberosities into the same horizontal plane, the brim of the pelvis will be found to look upwards and slightly forwards. This was at one time supposed to be the actual position in the erect posture ; and many persons now living may remember to have seen articulated skeletons in which the pelvis was so placed. Hence the term "horizontal," which use and wont has attached to the upper of the two rami of the pubis. JNaegele was the first clearly to show, not only that this was an error, but that it was a very gross one, 1 and that the pelvis was, in the normal position, inclined forwards to such an extent that the plane of the brim met the horizon at an angle of 60° or more (Fig. 13, a). The same observer, after examining a large num- ber of well-formed female bodies, concluded, further, that the average height of the promontory of the sacrum above the upper margin of the symphysis pubis is about 3} inches, and that a line drawn from the tip of the coccyx to the lowest part of the symphysis, formed with the horizon at b an angle which varies greatly, but which may be stated, as an average, at about 11°. In reference to this, however, it must be borne in mind, that the recession of the coccyx implies a movement downwards as well as back- wards, and that, conse- quently, this angle will be rendered still more acute during the passage of the child. The axis of the brim of the pelvis, then, is a line, c d, which passes upwards and strongly forwards, while that of the bony outlet is directed downwards and slightly backwards. The axis of the cavity is usually described as the perpendicular of a line drawn from the middle of the symphysis pubis to the centre of the sacro-coccygeal curve. \« Diagram showing the inclination and axis of the true pelvis. Das Weibliche Becken," etc. Carlsruhe. 1825. 42 THE PELVIS. [CHAP. Fig. 14. Axis of the True Pelvis. — If the bony pelvis were a simple cylinder, the demonstration of its axis would be a very simple matter. All that would then be necessary would be to make a section, perpendicular to its walls, when the axis of the cavity would be shown to be a line inter- secting the plane represented by this section, and equidistant from every part of the cylinder wall. The same simplicity of description will not, however, suffice in the case of the irregular and curved pelvic cylinder. What is known as the "curve of Carus" was at one time generally supposed to represent the axis of the pelvis. This curve is described in the following manner: The compasses are opened to the extent of 2J inches : one point is placed upon the central point of the posterior surface of the symphysis, while with the other a curve is drawn from the plane of the brim to the plane of the outlet, the segment of the circle thus indicated being assumed to represent the axis of the pelvis. A mere superficial observation of the human pelvis will serve to show that neither this nor the segment of any circle can truly, or even ap- proximately, represent the axis in question. Although not absolutely free from technical objection, we may assume that the following more modern view brings us much nearer the truth : If we produce the lines in the above dia- gram, which represent the planes of the brim and outlet, to their point of intersection in front of the symphysis at o, and from this common centre draw an infinite number of radii pass- ing through the pelvic cavity ; each of these radii may be held to represent the plane of that portion of the cavity through which it passes. If we then draw a line which shall pass through the geometrical centre of each of these planes, that line will be found to be a curve, which coincides very closely with the axis of the true pelvis, which is the segment of no circle, and which has been described as an irregular para- bola. One point must here, however, be noted — that as the terminal planes or radii will be modified by the motion of the coccyx during labor, so in like manner will the inferior portion of the curve be proportionally altered. This is indicated in the diagram, where the line cf marks the parabolic curve or assumed true pelvic axis. We must here be careful in drawing a distinction between the axis of the outlet of the bony pelvis, and that axis which represents the direction in which the child is born. In considering the latter, it is essential Diagram showing the axis of the parturient canal. II.] INTERIOR OF PELVIS. 43 that the soft parts forming the floor of the pelvis should be looked upon as constituting the posterior and inferior boundary of a continuation of the pelvic canal. These parts, which extend from the tip of the coccyx to the posterior commissure of the vagina, are subjected during delivery to an amount of stretching for which nature makes due pro- vision. The sphincter of the anus is dragged asunder, the perineum distends in all directions in a manner apparently incompatible with the integrity of that structure, until ultimately, at the moment of expulsion, the fourchette is driven downwards and carried forwards to such an extent, that a line drawn from the subpubic angle to the edge of the distended perineum, shows the plane of the outlet of the completed pelvic canal to look, not downwards, but almost directly forwards (Fig. 14, a b). The line e, perpendicular to, and meeting the centre of this plane, is then the axis of expulsion. The tendency of that part of the child which is first born is to move upwards and forwards under the pubic arch, and in front of the symphysis, in continuation of the curve indicated in the diagram by dotted lines. Let us now look more closely at the various parts of this tube which attract special notice, viz., the Brim, the Cavity, and the Outlet. The Brim presents (Fig. 11, p. 38) an irregular oval appearance, the long diameter of the oval being from side to side. It has been found on an average to measure in the antero-posterior or conjugate diameter, ap, which is taken from the promontory of the sacrum to the upper edge of the symphysis pubis, 4 J inches. Its greatest transverse measure- ment, 1 1, is 5J inches. In addition to these, there is also described an oblique diameter, extending from the sacro-iliac synchondrosis on each side to a point near the ilio-pectineal eminence on the other. This measures 5 inches, and it must be remembered that these diameters take their name "right" (r o), or "left" (I o), oblique according to the sacro-iliac synchondrosis from which they spring. 1 It will thus be observed that, in the skeleton, the transverse is the longest diameter of the three, but, when the soft parts are in situ, this is not the case, as the iliacus muscle overlaps the brim, so as to diminish the transverse while it scarcely encroaches upon the oblique diameter. The effect of this is that the oblique is practically the longest diameter, a fact which we find of great interest and importance when we study the relation of the diameters to the foetal head. The Cavity of the pelvis is the whole tube between the brim and the outlet. As a general rule, the deeper the cavity the more difficult is the labor, for in this case the pelvis approximates in its formation to the male type. If the diameters are proportionally enlarged, labor may be, it is true, quite easy; but the rule undoubtedly is that, in the case of the tall handsome woman with dignified gait and carriage, the probability of a difficult labor is much greater than in the short, wide- 1 In regard to this there unfortunately exists some discrepancy. The diameters are named right and left, as in the text, by the best English and German writers, but some eminent French and American authors have named them from the coty- loid cavity, thus inverting the meaning of the terms. 44 THE PELVIS, [CHAP. Fig. 15. Interior of pelvis, showing the ischial planes. hipped woman, in whom the swinging, or (to put it less gallantly) the waddling motion of her sex is more obvious. The cavity, as a single glance will show (Fig. 16), is deep posteriorly and shallow anteriorly. The average depth of the symphysis pubis gives the anterior depth at 1 J inches. The height of the planes of the ischia which corresponds to the middle depth may be stated as about 3J inches. The depth posteriorly may be set down, if we measure directly from the promontory of the sacrum to the tip of the coccyx, as 4J inches, which, if we follow the curve of the sacrum, will be in- creased to about 5 J inches, the former of these measurements making no allowance, however, for the yielding of the coccyx. Three diameters are also taken in the case of the cavity as representing its width : the conju- gate, from the centre of the symphysis pubis to the upper margin of the third sacral vertebra, 5J inches ; the transverse, from a point cor- responding to the lower margin of the acetabulum on one side to the corresponding point on the other, 5 inches ; and the oblique, from the centre of the great sacro-sciatic foramen on one side to the foramen ovale on the other, 5J inches. Looking now at the internal surface of the pelvic canal in a section such as is here shown, we may observe that the lateral wall is divided into two parts by a not very obvious line of demarcation (a b) leading downwards and backwards, from the ilio-pectineal eminence to the spine of the ischium. That part of the ischium which is in front of this looks slightly forwards, that which is behind slightly backwards. These are the anterior and posterior inclined planes of the ischium, sup- posed by Desormeaux, Tyler Smith, and many others, to determine the rotation of the head in the mechanism of parturition. To this, however, we shall return. While the brim or inlet of the pelvis is directed, as we have seen, upwards and forwards in the erect posture, that of the outlet, owing to the curve formed by the axis of the cavity, looks backwards, and, when the coccyx is extended, almost directly downwards. The conjugate diameter of the outlet (Fig. 16) extends from the lower margin of the symphysis pubis to the tip of the coccyx, and may be set down as 5 inches. In many cases the measurement is much less than this, and in any case the diameter may be increased to the extent of an inch or even more by the mobility of the coccyx during labor. The transverse, from one tuber ischii to the other, is about 4| inches ; and the oblique, from the middle of the lower edge of the great sacro- II.] PELVIC DIAMETERS. 45 sciatic ligament on one side to the point of union between the ischium and pubis on the other, also 4f inches. The facts which are brought out by those figures are chiefly these : (a) That the transverse measurement of the pelvic tube becomes pro- gressively diminished from above downwards, being greatest at the brim and smallest at the outlet. This is due, as a single glance down- wards in the axis of the brim will show, to the gradual approximation of the ischia (Fig. 11). (6) That the con- j ugate diameter is, on the con- trary, increased from above downwards, in consequence of the recession or curve of the sacrum, progressively from brim to outlet, if we allow for the bending back of the coccyx. These facts, which are associated with a remarkable rotation which the child undergoes during labor, are moreclearly shown when, as in the following table, the figures above noted are brought into juxtaposition. Along with these, a few of the more important of the many measurements which have been made of the female pelvis are also set down in inches, according to the average of the most recent and approved observations. Outlet of the female pelvis. MEASUREMENTS OF THE FEMALE PELVIS. 1. Circumferential measurement of the brim, 2. Between widest part of iliac crests, .... 3. " Anterior superior spines of ilium, 4. " Front of symphysis and sacral spines, True Pelvis. Brim, . Cavity, Outlet, Conjugate. Transverse. . o-i- 5 . 5 2 4| 17 10| 10i 7 Oblique. 5 [4|] All the measurements given in this table are, it must be remembered, those of the skeleton — no allowance being in any case made for the soft parts ; and to them we may add another measurement, which has an important bearing on practical considerations arising from the study of a certain class of pelvic deformities. This is the sacro-cotyloid diameter, which is about 3 J inches in a well-formed pelvis, and is rep- resented by a line drawn from the centre of the sacral promontory to the region above the cotyloid cavity. The encroachment of the psoas and iliacus muscles, with investing and other structures, reduces the 1 The oblique diameters of the cavity and outlet are placed in brackets, as, not being taken from fixed bony points, they are of comparatively little importance. 2 When coccyx forced back. 46 THE PELVIS. [CHAP. transverse diameter of the brim by about half an inch, while the other diameters of the brim, as well as of the cavity and outlet, are only reduced by an eighth to a quarter of an inch at the most. The oblique diameters are least of all affected ; but, owing to the presence of the rectum on the left side, the left oblique diameter is slightly shorter than the right. These facts have to be borne in mind in the course of examinations which are made with a view of estimating the capacity of the pelvis in its various parts, — a question often of vital import in the practice of midwifery ; and in such investigations it is also useful to know that the distance from the lower edge of the symphysis to the promontory of the sacrum is about half an inch more than the conju- gate of the brim. In regard to the measurements numbered 2, 3, and 4 in the table, if these are to be estimated by measurements in the living body, from two to three inches must be added for the tegumen- tary and other external structures. In addition to the angles which have already been described as formed with the horizon by the planes of the brim and outlet, and measuring respectively 60° and 11° (Fig. 13), and the subpubic angle, there are several others which should not be overlooked. The sacro-vertebral angle is that which the sacrum forms with the upper portion of the vertebral column, and is estimated as 117° in the male, and 130° in the female. This remarkable contrast serves to show that there is no gain whatever in capacity by a sudden recession of the sacrum, and that they who have assumed that in the female there is a more abrupt recession of the sacrum, are as much in error as those who have de- scribed the female sacrum to be more curved than the male. The symphysis forms with the horizon an angle of 35° to 40° in the erect posture; while the ischium forms with the ilium, or rather with the imaginary line leading downwards and forwards, and representing the mean direction of that bone, an angle of 110° to 115°. This latter is called the ilio-ischial angle? Development of the Pelvis. — From birth to the age of puberty, the pelvis differs in many respects, besides mere size and state of ossifica- tion, from the same part in the adult. At birth, the iliac fossa? are flat, and have their surfaces directed more forwards. The symphysis is short. The sacrum is very narrow, and on this account the transverse measurements are relatively smaller than the conjugate; while all the diameters are extremely small, and so insufficient for the reception of what are known as pelvic organs, that these parts are for the most part lodged in the abdominal cavity. This contributes, no doubt, to the abdominal prominence which is so familiar in the newly born. The sacrum is very flat, and there is also very little approximation of the inner surfaces of the ischium, which gives to the sides of the pelvis a general appearance of parallelism not existing in the adult. A very general idea prevails among the best modern writers that the inclination of the brim is considerably increased as compared with the adult. This has been stated by Cruveilhier and Burns, and even more decid- edly by Cazeaux. " The sacrum," says the latter, " is so flat and so 1 For a complete and exhaustive aVniv>nstration of these and other points alluded to, see Mr. Wood's Essay, Art. "Pelvis " in Todd's Cyclopaedia. II.] FLOOR OF THE PELVIS. 47 elevated, that a horizontal line drawn from the upper part of the pubis will pass below the coccyx." Mr. Wood, however, has given the weight of his authority in favor of another view, and states it as the result of his careful observations, made by sections when the soft parts were in situ, that he has always found the tip of the coccyx " as low as the lower border of the symphysis pubis." Such a serious discrepancy can only be accounted for by supposing that a different mode of obser- vation has been adopted. The child, it must be remembered, is not as yet structurally fit for the erect position, and therefore maintains for many months after birth a posture similar to that which it assumes in the womb, with the thighs flexed upon the abdomen, and the symphysis tilted upwards. To measure the pelvic angles of the child, with the view of comparing them with those of the adult, it is es- FlG - 17 - sential that the child should be placed in such a posi- tion as may, without violence or rupture of tissue, coincide as nearly as possible with the erect posture, and if this is done the pelvis will usually be found to present the appearance shown in Fig. 17. From this point of view Cazeaux is possibly correct ; but if a section be made through a child in the position which it instinctively adopts, the relative position of parts, as described and figured by Mr. Wood, will probably under these circumstances be confirmed. The other distinctive char- acteristics of the infant pelvis are also shown in the figure, in which, moreover, the general resemblance to the type of the Simiina may afford some pleasing suggestions to the disciples of Darwin. According to Burns, it is not until the tenth year that the transverse comes to exceed the conjugate measurement. There is, however, noth- ing which would enable us to distinguish with even an approach to certainty between the male and female pelvis until the period of puberty approaches, when nature, availing herself of the plastic nature of these bones, due to their tardy ossification, moulds the parts, in full view of the important physiological function which is about to be instituted, so that the marked characteristic features of the female pelvis are now rapidly developed. Hitherto we have looked at the pelvis as an osseous and ligamentous structure. Connected in the most intimate manner with it, however, there are certain soft structures which cannot properly be included in a description of the organs of generation, and which fall therefore to be considered' in this place. The fan-shaped iliacus muscle forms, along with the psoas on each side, a sort of cushion, which, besides giving proper support to other viscera, forms a rest for the gravid uterus, and an effectual protection for it against shock. It encroaches, as we have seen, upon the transverse, without materially lessening the oblique diameter, and this encroachment is more marked when the muscles are in a state of contraction. On each side of the cavity, there are two muscles covering in to a great extent the great sciatic and obturator gaps. These are the pyriformis and obturator internus muscles, to the contraction of which the rotation of the foetal head which takes place 48 FEMALE ORGANS OF GENERATION. [CHAP. within the cavity was supposed by Flam and of Strassburg to be due. The dimensions of the cavity are further reduced by the rectum and bladder, and by the cellular tissue, which, when overcharged with fat, may form a barrier to the progress of labor, rendering its course more tedious. The perineal strait, open in the skeleton, is occupied by firm con- tractile tissues, which form a floor for the support of the pelvic, and, indirectly, of the abdominal viscera. This floor consists of two mus- cular layers. Of these, the internal layer, formed by the levator ani and cocci/geus, has its concavity directed upwards, and has been named, not inappropriately, by Meyer the "pelvic diaphragm." The external layer, with its concavity downwards, is formed of the muscles of the perineum, known to anatomists as the sphincter ani, transversus perinei, ischio- caver mosus, and sphincter vagince. The pudic vessels and nerves, cellular tissue, the pelvic aponeurosis, an intermuscular aponeurosis, and the skin, complete this floor, which at the time of delivery becomes thin and distends to a very considerable extent. In the ordinary state, the measurement from the coccyx to the posterior commissure of the vulva is a little more than three inches ; but, during labor, the disten- sion is such that it is increased to 5, 6, 6J inches, or even more, by the stretching of the parts, and by overcoming the tonic contraction of the sphincter. CHAPTER III. FEMALE ORGANS OF GENERATION. A. External: labia; perineum; hymen, etc. — erectile tissue — the va- gina — GLANDS OF THE EXTERNAL ORGANS — ABNORMAL CONDITIONS — MAM- MARY GLANDS. B. Internal: the uterus: situation of; divided into body and cervix, AXIS OF UNIMPREGNATED UTERUS; CAVITY OF; FUNDUS; SURFACES AND BORDERS — SEROUS COVERING OF — BROAD LIGAMENTS; ROUND LIGAMENTS; VESICO-UTERINE FOLDS — THE FALLOPIAN TUBES — PAROVARIUM — FOLDS OF DOUGLAS — EQUILIBRIUM OF THE UTERUS. The Organs of Generation in the female include — besides the Uterus, Ovaries, and other parts situated internally — the Vagina, Vulva, and Mons Veneris. These latter being, more properly, external organs, anatomists have divided the whole into External and Internal Organs. External Organs of Generation. — Immediately over the symphysis pubis, above, and in front of the opening of the vulva or pudendum, is a firm cushion-like eminence, about two inches in depth and three inches transversely. This, which is called the Mons Veneris, varies in prominence according to the conformation of the pubes, and the amount of adipose and cellular tissue in it and the contiguous parts. After III.] THE PERINEUM. 49 puberty, it is covered with hair, and is abundantly furnished with sebaceous follicles, which were supposed by Moreau to contribute in some measure to the dilatation of the external parts at the moment of delivery. Continuous with this structure, extending downwards and backwards, and becoming gradually thinner in their course, are two rounded folds of integument, which, diverging from each other, leave in the median line an elliptical interval between them. These, are the labia majora, labia externa, or labia pudendi. They present an external surface, lined with skin similar to that of the mons veneris, and an internal surface covered with mucous membrane, which is the commencement of the genito-urinary tract. Behind, the thinner margins unite, forming the posterior commissure of the vagina. The fourchette, or framidum pudendi, is a transverse fold in front of this, which resembles and has been aptly compared to the continuation of the skin at the roots of the fingers, and is very generally torn in first labors. The depression between the fourchette and the commissure is named the fossa navicu- laris. Between the skin and superficial fascia of the labia there exists a purse-shaped sac, which has been described by M. Broca as analogous to the dartos tunic of the scrotum. This sac is filled with fat and cel- lular tissue, is the receptacle occasionally of hernia, and to it have been traced the terminal fibres of the round ligament of the uterus. The perineum extends from the posterior commissure to the anus, and is usually about an inch and a half in length. It is made up of highly distensible cellular tissue, and has been said to contain some yellow elastic tissue. It is undoubtedly susceptible of great distension during labor, without, under ordinary circumstances, any risk of rup- ture. On separating the labia majora, the labia minora or nymphaz are brought into view. These are two thick mucous folds, somewhat resembling the comb of a cock, about an inch and a half in length, having their origin on the inner surface of the labia majora, and becoming wider as they pass upwards and forwards, converging towards the clitoris, with the prepuce of which they are continuous. The clitoris is a small erectile tubercle, situated somewhat above the level of the lower margin of the symphysis pubis. Like the penis of the male, it has a suspensory ligament, two crura, two corpora cavernosa, and a glans, but has no corpus spongiosum nor urethra. Two muscles, corresponding to the ischio-cavernosus, are in the female called "erec- tores clitoridis." The vestibule is a small triangular space, bounded above by the clitoris, below by the urethra, and on either side by the diverging nymphse. It is about an inch in length, is smooth on the surface, and is specially important as a guide to the finger of the accoucheur in the introduction of the catheter — an operation which should always be performed, if possible, without exposing the patient. The meatus urinarius is indicated by a small projection, easily dis- covered by the finger, immediately beneath the vestibule, and in front of the vaginal entrance. The catheter being laid along the palmar surface of the forefinger, its point is guided towards the projection just mentioned, when, if the other extremity is gently depressed, it will usually pass in without the slightest difficulty. When the parts are 4 50 FEMALE ORGANS OF GENERATION. [CHAP. distorted by disease, or by the tumefaction which occurs after labor, it is often necessary to expose the patient before the instrument can be introduced. The urethra is about one inch to one inch and a half in length, highly distensible, and, in the unimpregnated state, almost straight. In young children, what may be called the urinary parts of the vulva are prominent, and it is not till the approach of puberty that the genital portion is observed to predominate. Behind and beneath the meatus, is the orifice of the Vagina, varying greatly in appearance and in dimension in young girls, in those who are no longer virgins, and in those who have borne children. In vir- gins, it is generally closed to a considerable extent by a thin fold of the mucous membrane called the hymen, which was at one time sup- posed to be the "seal of virginity/' but which may be ruptured by many causes other than coitus. Its usual form is crescentic, with the concavity upwards, closing in the posterior, and to some extent the lateral portions of the opening ; but it may present itself under various other forms. It has been frequently observed, for example, to be cir- cular, with a small perforation in the centre; or cribriform, with sev- eral perforations, as in a medico-legal case which the writer was called upon to examine ; or infundibuliform, or offering rarer peculiarities. In some instances, the closure is complete. But, whether complete or partial, or under whatsoever form it may present itself, the first effects of coitus are generally sufficient to rupture this fragile partition. In rare cases, however, its texture is so firm and resistant, that penetration is rendered impossible until the structure has been divided by the scalpel; and in cases of complete closure, where there is no question of coition, the operation may be necessitated from its being a barrier to the menstrual flow. When the hymen is absent, small projections, called caruneulce myrti- formes, generally about three or four on each side, are noticed on the margins of the opening. These were generally supposed to be the remnant of the ruptured hymen ; but, as they have been found to exist along with the hymen, this must be looked upon as open to doubt. Bloodvessels are supplied in abundance to all parts of the external generative organs, and in certain situations the masses of venous plex- uses which are termed erectile tissue are found in considerable quantity. The accompanying cut, from Kobelt, shows these structures carefully dissected. Besides the erectile parts already mentioned, there are, on either side of the vaginal orifice, two large leech-shaped masses, a, called bulbi vestibuli, which are about an inch in length, and are connected with the crura of the clitoris and the rami of the pubis, covered inter- nally by the mucous membrane, and embraced on the outside by the fibres of the constrictor vaginse muscle. A small plexus — the pars intermedia of Kobelt — has direct vascular connection with the bulbs. These erectile tissues receive their blood from the internal pudic arteries. The Vagina is a membranous and highly dilatable tube, which serves to connect the vulva with the uterus. It is situated in the true pelvis, between the bladder and rectum anteriorly and posteriorly, and the levatores ani muscles at the sides. Its axis is a curve, which corre- III.] THE VAGINA. 51 sponds in some degree to that of the pelvis ; and, in consequence, its anterior is shorter than its posterior wall, the former being about four, and the latter five or six inches in length. It is narrowest at the vulva, where it is embraced by the constrictor vaginae muscle, and widest at its middle part, where it is extended transversely, owing to its being compressed by the organs before and behind. The thickest part of the Fig. 18. External organs, partially dissected. (Kobelt.) tube is its anterior wall, where it is intimately connected with the bladder, and with the urethra, which is, as it were, imbedded in it. Its connection with the levatores ani muscles and the rectum is much looser, which admits of easy dilatation, and which also accounts for the fact that the rectum is rarely dragged down in uterine displacements, while the bladder is, from its closer connection, almost invariably altered in its relations. In the upper part of its posterior surface, it is separated from the rectum by a double fold of serous membrane, which forms a pouch of the peritoneal cavity. The external surface of the vagina is composed mainly of dense areolar tissue, beneath which there are two indistinct layers of muscu- lar fibres of the unstriped variety, the external being disposed longi- tudinally, while the internal are circular in their direction. Around the tube, a layer of loose erectile tissue has been found, which is most distinct at the lower part. Internally, it is lined throughout by mu- cous membrane, w T hich is covered with epithelium of the squamous variety, and is continuous in one direction with the skin and in the other with the mucous membrane of the uterus. Along the anterior and posterior walls, the membrane is slightly raised in the middle line, so as to form a ridge similar to the raphe in other parts. These ridges are called columnce rug arum ; and, at right angles to them, the mem- brane is thrown into numerous transverse folds (rugce), which are always 52 FEMALE ORGANS OF GENERATION. [CHAP. more distinct in those who have not borne children, and which are obviously destined to facilitate the dilatation of the parts. The upper part of the vagina embraces the neck of the uterus, which projects into the cavity from above, and in front. The vaginal mucous membrane is consequently reflected over the neck of the uterus some way above its mouth, the point of reflection being higher on the Fig. 19. Showing the relative position of the pelvic organs. posterior wall ; and it has been observed that the connection between the membranes and the subjacent uterine tissue is very firm close to the mouth of the womb, and is much less so as it approaches the point of reflection. This admits of the complete dilatation of the uterus, and the consequent obliteration of the neck. The other tissues of the vagina are continuous, or at least very closely united, with the corre- sponding tissues of the uterus. A reference to Fig. 19 will serve to show that the vagina terminates in a cul-de-sac above and behind the uterus, and that at this point its wall is for some distance in direct rela- tion with the peritoneal cavity, a fact of no little practical importance. The cul-de-sac of peritoneum with which it is in contact is termed the recto-vaginal pouch, and sometimes the pouch of Douglas. Further, the vagina may be considered as the organ of copulation in women • and as the canal which is destined to transmit the menstrual discharge, and, in case of pregnancy, the product of conception. It is abundantly supplied with vessels and nerves. The blood supply is III.] THE VAGINA. 53 derived from the vaginal and other branches of the internal iliac artery, and returns by means of corresponding veins, after forming at each side a vaginal plexus. The nerves have been traced to two sources, the hypogastric plexus of the sympathetic system, and the fourth sacral and pudic nerves of the spinal system. The external organs of generation are furnished with numerous glands of various kinds, which have been very fully described by MM. Robert and Hugnier. The latter divides the glands of the vulva and entrance of the vagina into sebaceous and muciparous follicles. The sebaceous variety is met with in great abundance over the whole of the parts from the genito-crural folds to the clitoris and nymphse. Those of the nymphse are exclusively sebaceous, and they all find their func- tion in the secretion of an oily fluid, which maintains the elasticity, moisture, and sensibility of the parts, prevents them from adhering, and, above all, protects them from the irritating action of the urine. The muciparous follicles differ essentially in their situation, and in the nature of the fluid which they secrete. Although here and there they are isolated, as a general rule they are found in groups. One such group of eight or ten follicles is found imbedded in the mucous mem- brane of the vestibule. Another is observed in the immediate neigh- borhood of the meatus urinarius, their orifices being extremely minute, and opening for the most part below the aperture of the meatus, upon, or close to, the little tubercle already described. A third group is described as external to these, and situated on either side of the urethra ; and a fourth, the orifices of which have been observed on each side of the vaginal opening, at the root of the hymen or carunculae myrti- formes. Under the muciparous class, two compound or conglomerate glands were long ago described by Bertholin, and more recently by anatomists under the name of the vulvo-vaginal glands. They are also called the glands of Duvernay, and are in many respects analogous to Cowper's glands in the male. They are about the size of a small bean, variable in form, and of a reddish-yellow color. Their development is said to proceed, pari passu, with that of the ovaries, reaching the maximum during the child bearing period, and being comparatively insignificant in youth and old age. They are situated one on each side, at the entrance of the vagina, beneath the superficial fascia, with their inner surface united to the vagina by areolar tissue, and the outer surface in relation with the constrictor muscle of the vagina. Each of the lobes of which the gland is composed gives origin to a little duct, all of which conduits ultimately unite at the internal and upper part, to form a com- mon excretory duct, which proceeds horizontally forwards as far as the vaginal orifice, where it terminates within the nymphse, and external to the hymen or carunculae myrtiformes. The orifice is very small and valvular, and is often only to be discovered with difficulty ; but its situation is usually indicated by an increased vascularity at the point whence it emerges. These glands secrete a fluid resembling that which is found in the prostate in the male, which is increased in quantity during coition, and is said to be expelled in jets, as occasionally occurs with the contents of the salivary duct. By lubricating the parts it 51 FEMALE ORGANS OF GENERATION. [CHAP. facilitates coition, and by preserving their moisture probably tends to maintain their extreme sensibility. The appearance and anatomical relations of the external organs of generation vary greatly according to age, and in consequence of vene- real indulgence, or of childbearing. At birth, the nymphse project beyond the level of the labia majora, and the parts in general look more forward than in the adult. When puberty approaches, hair appears on the pubes, the nympha? disappear between the labia, and the parts look downwards, so that in the erect posture nothing can be seen from before except the mons veneris ; whereas, in the child, the upper parts of the vulva are distinctly visible. The labia are symmetrical, thicker above than below, closely applied to each other, and of a fresh rose color on their mucous surfaces. Venereal indulgence, and still more, pregnancy and childbearing, modify, in a great measure, the appearance here described. The hymen is ruptured and replaced by the carunculse myrtiformes. The labia lose their regularity, and become of a more dingy hue on their mucous surface. The nymphae come again into view, partly by separation of the labia, and partly in consequence of hypertrophy of their tissue, while their vivid rose tint becomes replaced by a darker shade of color. In some cases the hypertrophy is very remarkable, and when so, is usually unequal on the two sides. This is said to be very common among Hottentot women, where the nymphse often become enormously enlarged. In women who have borne children the fourchette is usually ruptured, and the vaginal orifice remains large and irregular. The vagina again, which in virgins presents the appear- ances already described, may now lose, to a great extent, its rugae; and the deepening of its color is by some supposed to be a not unimportant sign of pregnancy. In women of advanced age, the vagina becomes contracted, being again thrown into folds, and greatly diminished in calibre. Its orifice shares in the contraction, the nymphre shrink, and the labia majora come once more into proximity, while the glandular, erectile, and other special tissues become atrophied. In a word, the characteristics of childhood are again in a great measure restored. Abnormal conditions, constituting some form or other of congenital malformation, are occasionally met with in the external organs. The labia may be imperfect or rudimentary, preserving in this respect the foetal condition of the parts; they may be developed on one side only; or they may present the appearance of several folds. In cases of deficiency of the lower part of the abdominal wall and of the bladder, along with separation of the symphysis pubis, the labia are imperfectly formed and set wider apart than usual. The posterior commissure of the vaginal orifice may be hypertrophied and pushed forwards so as to cover the aperture. The labia are, in some instances, adherent along the median line, to such an extent that an opening is left sufficient only for the passage of the urine. Induration and hypertrophy such as to constitute elephantiasis has also, although rarely, been noticed. Entire absence of the clitoris, unassociated with any other form of malforma- tion, is very rare. It is sometimes so small that it can with difficulty be discovered, and in these cases it might be erroneously supposed to be absent ; but it may be assumed that, unless other parts, such as the III.] MAMMARY GLANDS. 55 nymphse, are absent, the clitoris is only rudimentary. This organ is much more frequently enlarged, generally, no doubt, as the result of disease, but sometimes it is a pure hypertrophy of the normal tissues, when it may approach the dimensions of the penis and constitute one of the so-called forms of hermaphroditism. An extreme development of the nymphse — common, as we have seen, in certain races — may occasionally be met with as a peculiarity of structure ; and cases are even recorded where they have been found increased to two or even three pairs. The folds of which the hymen is composed, ordinarily thin and fragile, are occasionally developed to such an extent as to prevent sexual congress ; while, in some cases, it completely closes the mouth of the vagina, preventing not only coition and impregnation, but also menstruation, and, for the latter reason, if not for the former, rendering an operation necessary — which is usually a very simple one. Another condition of these parts which may call for operative interference, is what has been called vaginismus, where there exists such spasmodic contraction as prevents proper sexual contact, dilatation with or without the use of the scalpel being in such cases often found necessary. Con- genital absence of the vagina is by no means of very rare occurrence. In extreme cases, the whole organ is wanting — the vulva terminating abruptly at the point where the vagina, in the ordinary condition of parts, commences. In others, a portion of the tube exists, but ends in a cul-de-sac at some distance from the os uteri ; while, in another class, there is a narrow canal, sufficient only for the passage of the menstrual fluid. In many of these cases, free incision may be found necessary, in order, by giving egress to the menstrual discharge, to relieve the serious symptoms which arrest of that important function is apt to engender. A vertical septum occasionally exists, constituting the phenomenon of double vagina, in which, if complete, there is a hymen to each tube. More frequently, however, the septum is incomplete — either commenc- ing at the vulva and terminating so as. to leave the tube single at its upper part, or, conversely, commencing at the upper part and stopping short of the mouth of the vagina. In the latter case, we would expect it to be associated with double uterus. Transverse membranous septa also exist as congenital malformations, but much more frequently as the result of inflammatory action, or of the accidents of previous labors. Many of the conditions above detailed may give rise to serious im- pediments, either to delivery, to impregnation, or to the proper per- formance of the menstrual function, and, in consequence, delicate, and even dangerous operations may under such circumstances be required. Mammary Glands. — Intimately associated with the function of the reproductive system, are the glands, the presence of which serve to distinguish the class Mammalia. On this account, several modern writers have, with perfect propriety, included these organs in a descrip- tion of the external parts of generation. When they are fully devel- oped in a woman, they extend from the third to the sixth or seventh rib, and from the side of the sternum to the axilla, the left breast being generally the larger of the two. The nipple (niamilla) projects about 56 FEMALE ORGANS OF GENERATION. [CHAP. the level of the fourth rib from near the centre of the gland, and is, in the virgin, of a rose pink color. It is surrounded by a ring of similar hue (areola) varying in tint with the complexion of the individual. On the surface of this, several small tubercular projections are visible, on each of which are the orifices of several glands. 1 The tissue of the nipple is very rich in bloodvessels, and contains muscular fibres of the non-striated variety with a certain amount of erectile tissue, the surface being covered with papillae, which are highly sensitive. The tumes- cence of the nipple, which occurs under irritation, is usually attended with a pleasurable sensation. The bulk of the breasts, and what gives to them their smooth and moulded form, is chiefly fat, which, except at the nipple and areola, where the gland is contiguous to the surface, lies beneath the skin, and dips down into the intervals between the lobes and lobules of which the gland is composed. Each of these lobes is inclosed in a distinct cavity {loeulus, Fig. 20, 4), has a separate excretory duct, and is sub- divided again and again into smaller lobes, and ultimately into termi- Fig. 20. Dissection of the lower half of the female mamma during the period of lactation. (Luschka.) nal lobules. Within the latter, by a process of cell development, and multiplication of nuclei, the milk is eliminated from the surrounding vessels. The fluid, on the rupture of the cells, passes into the terminal ramifications of the ducts; which by their junction form larger canals termed galactophorous ducts. The milk being thus brought from the various lobes, these ducts, from fifteen to twenty in number, converge 1 These appearances are materially altered after impregnation. See Signs of Pregnancy. III.] AMMARY GLANDS. 57 towards the areola, beneath which they become considerably dilated into sinuses, 6, which serve as temporary reservoirs for the milk against the period of suckling. Between this and the nipple, the ducts again become contracted, 5, and proceed from the base of the nipple towards its summit without communicating, each discharging its contents by a special orifice. The walls of the tubes and sinuses are composed of areolar tissue, with longitudinal and circular elastic filaments. Irrita- tion of the nipple, either by the contact of the child or otherwise, causes a relaxation of the orifices, and at the same time, contraction of the walls of the sinuses, which may be looked upon as a reflex action, and which causes the milk to flow abundantly. Not unfrequently, a spasmodic contraction takes place independently of any special excite- ment, the result being the involuntary expulsion and loss of the milk. The well-known sympathy which subsists between the glands and other organs, such as the stomach and uterus, may give rise to similar phe- nomena; while that which exists between the breasts of each side often results in the spasmodic emptying of one gland while the child is at the other. 'The lacteal vessels are lined throughout by a mucous membrane, continuous at the nipple with the common integument, and which is invested by a tessellated epithelium. They are accompanied in their whole course by numerous lymphatics, which are connected intimately with those of the axilla and other neighboring parts. These lym- phatics are believed to take up the watery portion of the milk, and it is supposed to be by their action that frictions are beneficial in cases where we wish to diminish or arrest the secretion of milk. They receive their Fig. 21. Fig. 22. .^V^v K^ Structure of a lobule of the mammary gland. Ultimate glandular vesicles of the mamma. blood from the internal mammary, axillary, and intercostal arteries. The veins form round the nipple a circle or plexus, which is usually called the cir cuius venosus of Haller. In the latter months of preg- nancy, the pressure of the gravid uterus tends, as Mr. Nunn has pointed out, to increase from mechanical causes the quantity of blood in these vessels, and thus to promote the secretion of the gland. Fig. 21, from Henle, represents a section from a small lobule of the gland, magnified 60 diameters. 1, shows the stroma of the connective tissue which supports the glandular structure ; 2, terminal ramuscule 58 FEMALE ORGANS OP GENERATION. [CHAP. of one of the gland tubes ; 3, glandular vesicles. Fig. 22 shows several of the glandular vesicles, magnified much more highly, about 200 diameters. The secreting epithelial cells which line the vesicles are here represented, while the cavities contain a certain number of milk globules. In the male, the mammary gland exists, but is rudimentary. Various anomalies in structure have been met with, such as two or three nipples on one gland, or an additional mamma or even mammae. In the latter case, the supernumerary glands are usually near their ordinary site, but sometimes they have been found in a distant part of the body — as the axilla, thigh, or back. The Internal Organs of Generation. — These are the Uterus, the Fallopian Tubes, the Ovaries, with various ligamentous and other structures intimately connected with them. The Uterus, when unimpregnated, and at mature age, is, situated deeply within the true pelvis, between the bladder and the rectum in front and behind, and intimately connected at its lower part, as we have already seen, with the vaginal wall. The function which it has to discharge, is to receive the product of conception after it has passed through the Fallopian tube, and to maintain it within its cavity until, at maturity, it is expelled. The usual comparison of it to a pear, flattened from before backwards, gives one a very correct idea of its form. It is a hollow organ, with remarkably thick walls; and is so placed in the centre of the pelvis, that its upper part looks upwards and forwards, and its lower or vaginal part downwards and backwards. It is generally assumed, as sufficiently correct for all practical purposes, although by no means absolutely accurate, that its axis corresponds with that of the pelvic brim, or, in other words, that its axis, if carried downwards, would pass at the same time backwards, and cut the horizon at an angle of 30°. The uterus is divided into two parts : the body, which is much broader ; and the neck, which is nearly as long as the body, but much narrower. The point of division between these two parts is frequently indicated externally by a slight constriction. Till about the fourteenth or fifteenth year, this organ is of small size, but a considerable increase takes place at the period of puberty. In women who have borne children, its volume is permanently increased, although it is sometimes found in advanced age to have resumed in some measure the appearance presented in early life. It is temporarily increased in size during a menstrual period ; but if examined during the interval, the virgin uterus will be found to weigh on an average about 500 grains, and to measure, in length three inches, in breadth about two inches, and in thickness (i. e., from before backwards) one inch. Its situation varies according to age. In the foetus it is alto- gether above the brim, but from this position it gradually descends after birth, although it is not till the tenth year or even later that the fundus falls to the level of the brim plane. The uterus is, when healthy and normal, united with the surrounding parts by means of certain structures to be described presently. The nature of this union is essen- III.] THE UTEKUS. 59 tially lax, admitting of pretty free movement in all directions, which may easily be tested by the finger, and which enables it to accommo- date its position according to the degree of distension of the neighbor- ing hollow viscera. This laxity admits too of the free expansion of the uterus during the course of pregnancy, but unfortunately it may also give rise to certain displacements which will be duly considered in the proper place, in so far as these have a bearing upon the practice of midwifery. These displacements are prolapse or jwociclentia ; ante- version and anteflexion; retroversion and retroflexion; and lateral dis- placements ; terms which require no explanation. The axis of the virgin uterus must, therefore, be constantly chang- ing, now backwards and now forwards, according as vesical or rectal distension prevails. It is thus a matter of no little difficulty to deter- mine what may be regarded as the normal axis of the uterus, and in all attempts which have been made by anatomists with this view, it has been usual to consider the parts to be in their normal relative posi- tion when the bladder and rectum are each moderately distended. The opinion which is usually adopted, and which is founded on estimates of this nature, is, as has been said, that the axis of the uterus is iden- tical with the axis of the pelvic brim. It is admitted that, in many cases, and especially in those in which the vagina is very short, the fundus falls more or less backwards so as to bring the uterine axis more into a line with that of the vagina, while in some cases the uterus is curved so that the body forms an angle with the neck. This bending of the uterine axis, instead of being admitted as an exception, is recognized by many of the best authorities as the normal position of the womb, a view which careful personal observations leads us to confirm. It is a point of great importance, in making fig. 23. examinations on the living sub- ject, that it should be clearly recognized that the finger, on a digital examination, approaches the os uteri in a direction cor- responding to the axis of the vagina, which frequently forms nearly a right angle with the uterus. If this is overlooked, error is sure to creep into our calculations, as has evidently been the case in certain instances of inaccurate description of the anatomical relations of the womb. The opinion here ex- pressed as to the position of the womb is in accordance with that of Kohlrausch, as shown in his plates, and is confirmed by Dr. A. Farre in his admirable essay in the Cyclopaedia of Anatomy and Physiology, from which the diagram Diagram, showing relative position of pelvic viscera. (A. Farre.) 60 FEMALE ORGANS OF GENERATION. [CHAP. (Fig. 23) is taken. According to these able observers, when the blad- der b and the rectum c are moderately distended, the fundus of the uterus is directed upwards and forwards, and the neck downwards and very slightly backwards towards the orifice of the rectum. The relative heights of these parts are determined, it is assumed, by two lines : the one, a — a, being drawn from the lower border of the symphysis pubis to the promontory of the sacrum, to mark the height of the fundus; and the other, b — 6, carried from the same point anteriorly to the lower margin of the fourth sacral vertebra behind, to mark the plane of the orifice of the uterus. The line c — c indicates the axis of the body of the uterus. The representation, therefore, given in Fig. 23, is, as re- gards the position of the womb, probably nearly correct, subject, of course, to numerous modifications, in consequence of its mobility, and the influence exercised upon it by neighboring organs. The interior of the uterus corresponds in some measure with its ex- ternal surface. It is divided into two parts by a constriction not far below its middle, indicating the point at which the cavity of the cervix ends, and that of the body begins. This constriction, which is the usual cause of the difficulty experienced in passing the instrument known as the uterine sound, is called the os uteri internum, the orifice communicating with the vagina being named the os tinccje, os externum, or, more generally, the os uteri. In a profile section (Fig. 24) the an- Fig. 24. Fig. 25. ^^W Profile sectipn of the uterus. Lateral section of the uterus. terior and posterior walls are shown to be almost in apposition, this being, however, more complete at the internal os o. From this point the cavity of the body extends upwards to the fundus, while that of the cervix reaches downwards, and terminates at the external os. The neck of the uterus is divided, as will be observed, into two portions, upper and lower, by the point of reflection of the vaginal mucous mem- III.] THE UTERUS. 61 brane, the lower part being called the vaginal part of the cervix. Viewed thus, the os is composed, as may be noticed, of two lips, a, an- terior, and p, posterior, of which the former is generally described as the longer. This, however, which is more apparent than real, is caused by the position of the uterus as regards the pelvis, which brings the anterior lip lower in the vagina, and thus makes it seem longer than it really is in reference to the long axis of the organs. The vagina reaches somewhat higher on the posterior than it does on the an- terior lip. If we now make a transverse section as shown in the accompanying diagram (Fig. 25), it is to be noticed, in the first place, that the cavity of the cervix, as well as that of the body, is expanded from side to side, owing to the approximation of the anterior and posterior walls as shown in the previous figure. The cavity of the cervix then is, being some- what flattened from before backward, irregularly fusiform. Its lining membrane presents a peculiar appearance, being thrown into irregular folds, which branch laterally from a raphe or median line, in a direc- tion generally upwards. This arborescent appearance has given rise to the name under which it is known to anatomists, the arbor vitce uterinas, and it has been observed that, in the uteri of very young children, these folds are traced much higher than in the internal os, which is their limit in the adult. The cavity of the body is from this point of view triangular in shape, smooth on its surface, and having three open- ings leading into it, one at the internal os or apex of the triangle, and one at each angle of the uterus, leading right and left into the Fallopian tubes. Some rare instances of congenital absence of this cavity have been recorded: what is more common is adhesion of the walls in old age. The os uteri, as felt by the finger, or as seen through the speculum, is a transverse opening or slit, which, in the virgin, and in the ab- sence of structural disease, is perfectly smooth. In these circumstances, the aperture is closed, but the depression between the lips is easily felt, and is precisely similar, in the impression it communicates to the finger, to the sen- sation experienced when the finger is applied to the tip of the nose. In this case the cartilages represent the firm tissue of the lips, while the vertical in- terval between them corresponds to the transverse slit which constitutes the os. The characteristics above described are those of the virgin, or, as Dr. Tyler Smith more correctly calls it, the " nulliparous " uterus. During pregnancy, the organ is enormously distended, and the ana- tomical relations of the contiguous parts are greatly disturbed. After delivery, the parts contract, and regain in a great measure their original appearance and condition, but they nevertheless retain features of dis- similarity which generally enable the observer, on a careful examina- tion, to distinguish the uterus of a woman who has been a mother. The Fig. 26. 62 FEMALE ORGANS OF GENERATION. [CHAP. chief points of distinction are as follows : The weight of the organ is increased, according to Meckel, to about an ounce and a half; the fundus and body are rounded externally ; the cavity of the body loses its triangular shape, and becomes much larger relatively to the cervix, the os internum being agape. The arborescent folds of the cervix are in a great measure obliterated, or at least are rendered indistinct, and the os externum is patent. The differences in the latter are, from the fact of its being of easy access to the finger, of special importance, and consist mainly in an enlargement of the parts, and an irregularity in the surface of the lips, which are now no longer smooth, but puckered round the edge of the os, and often nodulated on the surface. These irregularities are due to slight lacerations of tissue which occur during delivery. They are always more marked in women who have borne many children, where the lips are not unfrequently divided into lobes by shallow furrows, representing these lacerations, and which radiate from the os as from a centre. These fissures are generally observed at the sides or angles of the os, and are, according to Cazeaux, much more marked on the left than on the right side. The uterus, then, as may be inferred from what has been said, pre- sents a fundus, more or less rounded according as the woman has or has not borne children, two borders laterally, and an anterior and posterior surface, of which the latter is the more convex. It consists of three constituent layers : a serous or investing coat ; a mucous or lining coat ; and an intermediate thick layer of fibro-muscular structure constituting the proper tissue of the uterus. Each of these requires special and very careful consideration. The Sei*ous Coat — Along with this, we shall consider certain structures very intimately connected with it, which are described as the Ligaments of the Uterus. The great serous membrane, which invests almost the whole of the abdominal viscera, is also reflected over the greater part of the womb. Passing backwards over the fundus of the bladder, the peritoneum becomes reflected upwards on the anterior surface of the uterus from a point which in the virgin uterus is about midway between the os externum and internum, a space being thus left (see Fig. 19) through which direct communication may take place between the uterus and the bladder. This may occur as an accident in midwifery practice, constituting a vesico-uterine fistula, as in a case reported by the writer. 1 From the front to the back of the uterus, the membrane now passes over the fundus, and investing the whole of the posterior surface with the exception of the vaginal portion, reaches downwards behind the vagina, in the manner already described, to form the pouch of Douglas. The manner in which the uterus is thus embraced by the peritoneum in its course from before backwards is peculiar. Instead of investing the lateral parts of the organ in the same manner as the anterior and posterior walls, it is stretched from side to side of the pelvis, forming, in fact, a double layer of peritoneum, in the centre of which the uterus is confined. These folds, intimately connected on either side with 1 Glasgow Medical Journal, 1862. III.] RELATIVE POSITION OF PELVIC ORGANS. 63 important organs to be presently described, are the broad ligaments of the uterus. Looking from above downwards in the axis of the brim, it will be noticed that the broad ligaments, with the uterus, u } form a partition or Fig. 27. Pelvic organs in silu, viewed in the axis of the hrim. (After Schultze.) curtain, dividing the cavity of the pelvis into two parts, anterior and posterior, of which the anterior is occupied mainly by the bladder, b, Fig. 28. Anterior view of the uterus and its appendages. (Quain.) and the pouch which separates it from the womb, and the posterior by the rectum, r, and the pouch of Douglas. It will also be observed 64 FEMALE ORGANS OF GENERATION. [CHAP. that the greater convexity, and, indeed, the bulk of the uterus, projects into the posterior of the two cavities. The attachment of the broad ligament is in point of fact to the anterior lip of the lateral border of the womb. If, therefore, the uterus and the broad ligament are viewed from before, as in Fig. 28, the fundus and body of the uterus are indeed indicated, as well as the situation of other parts to be mentioned im- mediately, and the relation which they all bear to the vagina ; but the parts themselves are only to be distinctly demonstrated by turning our attention to the posterior surface of the pelvic partition, as shown in Fig. 29, where the posterior wall of the uterus has been removed, in Fig. 29. Posterior view of the uterus and its appendages. (Quain.) order to show the interior of the organ. The peculiar structure of the cavity of the cervix, the anterior lip of the os, and the anterior wall of the vagina are also shown, as also the triangular space bounded infe- riorly by the ovary and its ligaments, which, from a fanciful resem- blance to a bat's wing, has been called ala vespertilionis. It is thus very apparent that the effect of the broad ligament is to maintain the uterus in its central position as regards the pelvic cavity, and to prevent its displacement downwards, while it admits of very free antero-posterior movement, corresponding to the distension of the bladder or rectum. Between the two layers which constitute the broad ligament, and occupying each a fold more or less distinct, are the following structures : the round ligament (see Fig. 27), a cord-like bundle of fibres, partly muscular, and about four and a half to five inches in length, which has its course on each side from the angle of the uterus, first upwards and outwards, and then forwards and a little inwards to the internal ingui- nal ring. Passing, like the spermatic cord in the male, through the inguinal canal, and invested by a peritoneal sheath called the canal of Nuck, its fibres expand and are lost in the mons veneris, some of them having been traced to the purse-shaped cavity in the labia majora already described. According to Madame Boivin, the ligament of the right side is a little shorter and thicker than the other. Two small III.] LIGAMENTS OF UTERUS. 65 semilunar folds are seen on this aspect, which are formed by the peri- toneum in its passage from the uterus to the bladder, and which limit laterally the pouch existing between these two organs. They are called the vesico-uterine ligaments. The uterus is generally observed to be a little more to the right than to the left side ; and it is asserted by Schultze that in the normal position it is somewhat twisted on its axis, so as to turn the anterior surface a little to the right. On this obser- vation is grounded a theory which Schultze has propounded as to the position of the child in the womb. All this is shown in Fig. 27. Reverting now to the posterior surface of the broad ligament, we find several parts which are of the highest physiological importance. At the upper or free margin of the broad ligament, and occupying a portion of the space between its layers, there extends from each angle of the uterus a thick cord, between three and four inches in length, at first nearly straight in its direction, but in its outer half pursuing a somewhat tortuous course, especially in young subjects. This is found, on dissection, to be traversed in its whole extent by a canal of small diameter, and is familiarly known to anatomists as the Fallopian tube [oviduct). It is composed in a great measure of muscular tissue of the non-striated variety, which is disposed in layers, an external one of longitudinal, and an internal of circular fibres. Along with this is areolar tissue, the whole being embraced by the peritoneum in the manner described. The canal is lined with mucous membrane, with an epithelium of the columnar and ciliated variety, continuous at one extremity with the mucous membrane of the uterus, and at the other with the inner surface of the peritoneum — a unique example of a mu- cous being continuous with a serous membrane, and of a serous cavity which is not absolutely a closed sac. The tube is small, and its cavity narrow at the uterine end, barely permitting the passage of an ordinary bristle, but it becomes dilated in its course outwards, and ultimately expands into the trumpet-shaped extremity from which it derives its name {tuba). The mucous membrane lining the canal is disposed in longitudinal folds, so that in a transverse section of the structure the cavity presents a stellated appearance. The mouth of the tube has a very irregular and fringed margin, hence its name of fimbriated ex- tremity — the fimbria? being arranged in a circular manner, and sur- rounding the orifice, which looks downwards in the direction of the ovary. With this organ it is in fact connected by the elongation of one of the fimbria?. When the ovum comes to maturity within the ovary, that portion of the organ from which it is about to escape by dehiscence is firmly grasped by the fimbria? (morsus diaboli), and the ovum is received into the oviduct, and by it conducted to the uterus, where it is retained and developed, or whence it is discharged, according to circumstances. Leading from the inner extremity of the ovary — an organ to be hereafter described — is a dense cord, composed mainly of fibro-areolar tissue, but containing also muscular fibres. This is the ligament of the ovary, which is also, like the round ligament and the Fallopian tube, firmly united to the angle of the uterus at a point behind and below the latter, and is about an inch and a half in length. The parovarium, 5 66 FEMALE ORGANS OF GENERATION. [CHAP. or organ of Rosenmiiller (Fig. 30, p o), is situated between the layers of the broad ligament, and can usually be brought into view by holding up to the light that portion of the ligament which is between the outer part of the ovary and the Fallopian tube. According to the observa- FlG Diagrammatic view of the uterus and its appendages as seen from behind. (Quain.) tions of Kobelt and Follin, the parovarium is usually composed of from seven to ten tubules, which are convoluted and end in a cul-de-sac, all converging towards the tube through which the vessels of the ovary pass. These tubes exist at all ages, but are more distinct in children, and still more so in the foetus. In no instance have they been found to have an orifice, but there seems good reason to believe that they correspond to the epididymis of the male, more especially the coni vasculosi, and are therefore the vestiges of the upper part of the Wolffian bodies of the embryo. It is more than likely that the little cysts so frequently found in this situation, which are usually pedicu- lated, have some anatomical connection with the parovarium. From the back of the uterus on each side, crescentic folds of peritoneum pass backwards towards the rectum (Fig. 27). They are more marked than the vesico-uterine folds, previously described, and are called the posterior or recto-uterine ligaments, or folds of Douglas, as they mark the upper boundary of the pouch with which the name of this anato- mist is associated. That muscular fibres exist between the layers of the broad ligament is a question no longer open to doubt ; and there seems good reason to believe, from the researches of Rouget and others, that this is only a portion of a continuous envelope of muscular fibres, embracing the uterus, Fallopian tubes, and ovaries. These fibres are believed to exercise an important physiological function, in bringing all the struc- tures into harmonious action, and more especially in insuring the pre- cision with which the fimbriated extremities of the Fallopian tubes grasp the ovaries. The uterus is thus — by means of its ligaments and other auxiliary structures — so suspended in the cavity of the true pelvis as to admit, as has been shown, of tolerably free movement ; and, at the same time, to IV.] MUCOUS MEMBRANE OF UTERUS. 67 restrict its mobility within certain limits. The movement of the body from side to side is curtailed effectively in a healthy state of the parts, by the broad ligament, while displacement backwards is prevented by the vesico-uterine folds and the round ligament, and movement in the contrary direction by the recto-uterine ligaments. Undue importance must not, however, be attached to the function of these structures as ligaments ; for it is very obvious that other parts (and in an especial degree the vagina) aid them in holding the uterus thus in suspension. The general laxity of all these tissues, however, which nature permits in view of the higher function of the uterus, is very apt, under disturb- ing influences, to give rise to displacements which have already been named, but the consideration of which belongs more properly to the department of gynaecology. It may, however, be observed that the symptoms of these displacements are, in a great measure, mechanical, and the direct result of the loss of equilibrium — as those, for example, which arise from pressure on the bladder or rectum, and the pain in the groin frequently experienced in retroversion, which is assumed by Cazeaux to arise from tension of the round ligament. In the interval between the two layers of the broad ligament, and associated with the other structures above described, there is found a considerable quantity of loose and extensible cellular tissue. This admits of the complete alteration in the anatomical relations of the parts which occurs during pregnancy, and which is further provided for by the manner in which the uterus is attached to its serous investment. The nature of the connection is firm at the fundus, and lax at the sides, where the peritoneum may be moved by the finger to and fro upon the subjacent tissue of the organ. The manner in which the neigh- boring parts accommodate themselves to the distension of the womb during pregnancy will fall to be considered in a subsequent chapter. CHAPTER IV. FEMALE OKGANS OF GENEKATIO^ (Continued). OF THE PROPER TISSUE OF THE UTERUS — OF THE MUCOUS LAYER ; ITS STRUC- TURE AND GLANDS, IN THE BODY AND CERVIX — BLOODVESSELS OF THE UTERUS — LYMPHATICS AND NERVES — MALFORMATIONS AND ABNORMAL CON- DITIONS — THE OVARIES : THEIR STRUCTURE — THE GRAAFIAN VESICLES AND THEIR DEVELOPMENT — THE OVUM— PHENOMENA OF OVULATION — FORMATION OF THE CORPUS LUTEUM — THE CORPUS LUTEUM OF PREGNANCY DISTIN- GUISHED. The Proper Tissue, which lies immediately beneath the peritoneum, and which constitutes the greater part of the walls of the uterus, is very dense in structure, and, except during pregnancy or a menstrual period, is of a grayish color in section, and displays numerous bloodvessels, 68 FEMALE ORGANS OF GENERATION. [CHAP. some of them of considerable size. It is thickest at the middle of the body and at the fundus, thinnest at the Fallopian tubes, and is com- posed throughout of bundles of muscular fibres of the plain variety. These fibres in the unimpregnated condition are interlaced, disposed very irregularly in bands and layers, and mixed with fibro-areolar tissue, which is more abundant near the external surface. As in the case of other hollow viscera, the muscular elements may be described as con- sisting of an external layer, the fibres of which have a general longi- tudinal direction, and of an internal or circular layer. From the irregular manner, however, in which, in the unimpregnated uterus, the bundles of fibres are disposed, and the intimate union which subsists between them, this seems on the first glance to be somewhat of a forced analogy. And it would probably remain so, were it not that during pregnancy the stratification of the muscular tissue becomes much more distinct, so as to render the comparison quite justifiable, a fact which will be brought out more clearly afterwards. Anatomists usually divide this tissue into three layers, external, intermediate, and internal. 3fucous Membrane. — The very existence of this membrane was long disputed, the obvious reason being that it differs so much from other mucous membranes, that physiologists, with some show of reason, refused to admit the analogy. More modern and more exact observa- tions, however, leave no doubt in these days as to the propriety of classifying it as it is here named. The descriptions which are usually given of this membrane by anatomists are very meagre, and in some respects inaccurate; this may serve as our warrant for examining its structure and functions a little more in detail than under other circum- stances might have been necessary. Although often described as a thin membrane, it is, on the contrary, probably the thickest mucous mem- brane in the body, constituting, according to M. Coste, in the cavity, about one-fourth of the entire thickness of the organ. In this situation, it is of a reddish tint, but in the cervix, where it is much thinner, it is paler in color, the thinning occurred somewhat abruptly at the os inter- num. It is firmly adherent to the subjacent muscular tissues, and can- not, in consequence of the sparseness of the submucous cellular tissue, be made to glide upon the part which it covers. The surface of the mem- brane is smooth, and abundantly studded over with minute dots, which are found on closer examination to be the orifices of numerous utricular glands, which run through the entire thickness of the membrane in a direction perpendicular to its surface. Fig. 31 represents a part of the cavity of the uterus which shows in section — a, the orifices of the glands, and d, the glands themselves. They were believed by Weber, and are here represented, as being, at the commencement of pregnancy, greatly convoluted, and sometimes bifurcated at the extremities. The more recent and exact observations of M. Robin show, however, that when in situ, they are rather undulated than convoluted, that they are never spiral, although, as in Fig. 32, they may appear so when separated, and never bifurcating. During pregnancy and menstruation, they become greatly enlarged, and sometimes cross each other, an ap- pearance which in all probability has led to the idea of a division of the tube. They are simple utricular glands, parallel to each other, IV.] MUCOUS MEMBRANE OF UTERUS. 69 ending in a cul-de-sac, and permeating the entire membrane. They are lined by nucleated ovoid epithelial cells, their walls being finely granular, and very firmly adherent to the tissue which intervenes between them. Their length measures exactly the thickness of the JSmm Fig. 31. MB >MM,&kt?$ mnmmw^^- l Utricular glands of uterus. (E. H. Weber.) mucous membrane, and is least, therefore, where the' membrane be- comes thinner, on its approach to the os internum and the orifice of the Fallopian tubes. " If we except that of the stomach/' says M. Robin, 1 Fig. 32. Fig. Utricular gland of the uterus. (Coste.) Relation of utricular glands to muscular tissue of uterus. (Coste.) " there is no mucous membrane more rich in glandular follicles than that of the uterus." In the pig and some other animals the epithelial cells which line the glands are ciliated. In the unimpregnated uterus, in an intermenstrual period, the utric- ular glands are not very easily seen ; but if their sections are treated with acetic acid or concentrated tartaric acid, and viewed by transmit- ted light, they can generally be made out. They terminate quite abruptly at the inner margin of the muscular coat, the point of junc- tion being very distinctly indicated by the muscular fibres running at right angles with the tubes. The glands were supposed by Sharpey to penetrate the muscular tissue, but this view is now generally re- garded as an erroneous one. Their abrupt termination is well shown by a reference to Fig. 33. In the same preparation, which was taken De la Muqueuse Uterine. Paris, 1861. 70 FEMALE ORGANS OF GENERATION. [CHAP. from the uterus of a young girl who had committed suicide in the intermenstrual period, is also shown the general direction of the fibres composing the proper tissue of the uterus, p, as compared with the course of the tubules from the free surface of the mucous membrane at m. At a the tubes are cut across, and shown obliquely in section, and the course of the bloodvessels which accompany them is also indicated between m and the adjacent part of the muscular tissue. Fig. 34, also taken from Coste's beautiful plates, shows a detached portion of the mucous membrane in the same case. Little funnel- shaped depressions are shown at a, into which the orifices of the tubes open. The actual glandular orifices are distinctly shown elsewhere on the surface of the membrane. From one portion, the epithelium has been stripped off, so as to show the termination of the tubes free and floating. But what is most distinctly shown here, is the perfect net- work of vessels which surrounds the orifices, which is always to be observed most distinctly at those seasons when the functional activity of the uterus is excited. Fig. 35 is a small portion of the mucous membrane as observed after recent impregnation. This specimen is represented as viewed upon a Fig. 34. Fig. 35. Termination of utricular glands on mucous surface of uterus. Utricular orifices of uterus. (Sharpey.) dark ground, and also shows the orifices of the uterine glands, in most of which, as at 1, the epithelium remains, and in some, as at 2, it has been lost. The mucous membrane is smooth on its surface, which is composed of columnar and ciliated epithelium. Cruveilhier describes it, how- ever, as presenting indistinct papillae, while some earlier physiologists insist that it is studded with free villi : errors which have probably had their origin, as M. Robin assumes, in the extremities of the gland- ular follicles becoming liberated from their epithelial attachment by post-mortem change, and which find in analogy an apparent corrobora- tion in the condition of the membrane as observed in the uterine cornua of some mammalia. During pregnancy, the epithelium becomes transformed ; it loses all trace of the vibratile cilia, and the cells are changed from the columnar to the pavement variety. IV.] BLOODVESSELS OF UTERUS. 71 Berres 1 was the author of the erroneous hypothesis that the villi of the placenta plunged into these glands to be there bathed in materials destined for the foetal blood, a view which was afterwards supported by Bischoif, 2 but which now receives little if any support. M. Coste 3 was undoubtedly the first who gave a complete description of the mucous membrane during menstruation and the various stages of pregnancy. To him the merit is also due of having first demonstrated, what is now all but universally admitted, that the maternal covering of the ovum (decidua), of which we shall have more to say, is not a new formation, as Hunter taught, but is the mucous membrane itself, altered and modified to suit the circumstances of the case. The views of Coste have received the most remarkable confirmation by the subsequent observa- tions of Richard, and by the still more recent researches of Robin. The mucous membrane of the uterine cavity is continuous at the angles with that which lines the Fallopian tubes. At the internal os, it becomes much thinner, with fewer glands, and loses many of its special characteristics as it passes into the cavity of the cervix. The presence of the folds, which give to it in this situation an arborescent appearance, has already been noticed. The extent of the inner surface of the cervix is thus greatly increased, an arrangement which not only admits of free dilatation of the parts, but also furnishes a greatly in- creased secretory surface. It has been computed by Dr. Tyler Smith that, in a well-developed virgin uterus, the follicles of the cervix (gJandulce NabotJd) are not less in number than ten thousand. These glands secrete a clear tenacious fluid, which is alkaline in reaction, and which is often seen on vaginal examination to occupy the os externum, and they are liable during pregnancy to a very remarkable hypertro- phy. The mucus which lubricates the parts during delivery is mainly derived from this source, and in certain morbid conditions it is greatly increased in quantity, when it is either secreted of an acid reaction, or loses its alkalinity, and also its transparency, by contact with the acid mucus of the vagina. The cavity of the cervix is lined with an epithe- lium which in its lower half is squamous like that of the vagina. About midway between the outer and inner os, it assumes the charac- teristics of the ciliated and columnar epithelium of the cavity. The uterus is supplied with blood from two sources. The ovarian arteries have their origin, like the spermatic in the male, from the aorta, at a point a little below the renal arteries. Passing over the psoas muscles, and occupying a fold in the peritoneum, which is indi- cated in Fig. 27, they pass between the layers of the broad ligament — forming what have been described as the ovario-pelvic ligaments. They follow, in their passage towards the ovary, an extremely tortuous course, which admits of free distension during pregnancy without any risk of diminution of their calibre. Giving off branches to the ovary and round ligament, they now pass inwards to join the uterine arteries on each side. These latter spring from the interior division of the in- 1 Medicinische Jahrbiicher des K. K. (Esterreich. Staates. Wien, 183^ 2 Traite du developpement de l'homme, etc., 1845. 3 Histoire du developpement des Corps Organises. Paris, 1847. 72 FEMALE ORGANS OF GENERATION. [CHAP. ternal iliac, pass between the layers of the broad ligament downwards towards the neck of the uterus, then upwards, pursuing, like the ovarian arteries, a very tortuous course, and, giving off numerous branches to the uterus, effect a union with the ovarian. Frequent anastomoses take place, and the branches may be seen to lie in little canals or channels on the surface of the womb, before they penetrate more deeply. The veins correspond to the arteries just named, and are of considerable size. They form plexuses, which communicate freely, and during pregnancy their calibre becomes enormously in- creased. Within the substance of the uterus, the ramifications of the arteries retain their spiral form, but become straighter as they approach the mucous membrane, where fine branches surround the utricular glands, and ultimately form, as has been shown (Fig. 34), a fine net- work on the free surface of the membrane. The veins which convey the returning current are, at their origin, of small size, but become much larger within the substance of the womb, attaining during preg- nancy a size so considerable that they are designated the uterine sinuses. The cervix is very much less vascular than the body and fundus. Numerous lymphatics, which are fully developed only during preg- nancy, have been traced to the uterus. Some doubt still exists, how- ever, as to the precise source of the nervous supply. All agree that the chief supply is from the sympathetic system, — the hypogastric, renal, and inferior aortic plexuses being all believed to contribute. An idea generally entertained is, that the sacral nerves send some filaments to the cervix, but this has been denied by Dr. Snow Beck, 1 who failed in his dissections to discover any single filament proceeding from this source. M. Jobert has asserted, again, that no nerves whatever are sent to the vaginal portion of the cervix ; but this has been warmly refuted by M. Boulard. There can be no doubt that the presence in the cervix of filaments from a cerebrospinal source, or the absence from its vaginal portion of all nerves whatever, are both observations which, if confirmed, would tend to throw some light on certain phys- iological and pathological facts. While, as a rule, in the Mammalia, the vagina is single, the contrary is the case as regards the womb. In the female human embryo, the uterus is formed by the median fusion of the lower parts of the ducts of M tiller — which are the efferent tubes of the rudimentary generative apparatus. These meet together inferiorly, become gradually united from below upwards, and ultimately form a single cavity by the ab- sorption of the partition between the two, so that there is a stage in development, at which the human uterus is composed of two separate and distinct tubes. It follows, from the manner in which they become united, that there is a series of subsequent stages at which the partly developed organ may be termed uterus bicollis — when the necks are still separate; bieorporeus — when the union has reached the os inter- num; bifundalis — when the fundus alone is divided; biangularis ; and, finally, the uterus simplex — the highest or perfect human form. In the other Mammalia, the process is so far identical, but may be 1 Philosophical Transactions, 1846. Part II, p. 219. IV.] UTERINE MALFORMATIONS. 73 arrested at any stage to form the uterus natural to the group to which the individual belongs. In the Marsupials, not only are the uteri separate, but also the vaginas. In a large number of the Rodents, the vagina is single, and into its fundus two distinct uterine cavities open by separate apertures ; while, in some, there is a partial separation of the vagina for about a third of its length. The commencing union of the cervix is shown in some groups of the same order — as the MuridaB — where there is a very short common cavity. The confounding of the two uterine cavities may be traced in various progressive stages by an examination of the internal organs of certain of the Carnivora, the Ruminants, the Ungulata, the Edentata, and the Simiina ; but even in women there still remains in the angles of the uterus a trace of the original bifurcation. This reference to the development of these parts, and, for the analogy, to their condition in the lower animals, will be found to throw light upon certain cases of malformation or peculiarity of structure in the human subject, which apparently consist, for the most part, of a simple arrest of development. Taking the particulars above noted as a basis of classification, we may adopt the division in regard to those abnor- malities which Dr. A. Farre, in his essay on the uterus, 1 has selected as the best. Of this section of his admirable monograph, the following remarks are in great part an abstract. Group 1. Complete absence of the uterus, both of the ducts of Miiller being imperfect or undeveloped. In the cases of total absence of uterus which have been recorded, it seems certain that, in a very large proportion at least, something of a rudimentary organ existed in the fold of the peritoneum lying behind the bladder, and representing the broad ligament. They usually occur under the form of two hollow rounded cords, or bands of uterine tissue, extending upwards towards the ovaries. The vagina may be absent or rudimentary, as also the Fallopian tubes ; but it is interesting to observe that the ovaries may be perfect in these cases — a fact easy of explanation, when we remem- ber that the ovary is formed out of a separate portion of blastema from the Wolffian bodies and duct of Miiller. Group 2. One uterine cornu only may retain the imperfect condition last described, while the second develops, so that we now have what has been called the uterus unicornis. In this condition, which repre- sents the type of the normal condition in birds, both ovaries may be found perfectly developed. Group 3. When development progresses in both cofnua, and these do not, as under ordinary circumstances, unite, various peculiarities result, which cause the uterus to assume, according to the degree of the malformation, a type which is lower or higher in the animal scale. " The marsupial type/' says Owen, " is repeated in one of the rarer anomalies of the female organs in the human species." This, indeed, is an anomaly so rare and peculiar, that it has only been observed as coexistent with other malformations, — such as fissure of the abdomi- nal and pelvic walls ; but what is more frequently met with is the form 1 " Cyclopaedia of Anatomy and Physiol ogy." Art. " Uterus." 1859. 74 FEMALE ORGANS OF GENERATION. [CHAP, shown in Fig. 36, where the two uterine halves meet, and are united by a commissure of true uterine tissue, which represents the fundus uteri. The higher this commissure reaches, the more does the womb approach to the normal type. In the figure there are two vagi me, two orifices, and two uterine cavities. In the case shown in Fig. 37, there is but one vagina. The os also is single, as is the cavity of the cervix, the bifurcation commencing Fig. 36. Fig. 37. Double vagina and uterus. (After Busch.) Bifid uterus. about the os internum. The angle at which the cornua unite varies in different cases — which is accounted for, as is pointed out by Rokitansky, by the height at which the uniting commissure is situated. Group 4. In this, the external form of the uterus differs but little from the normal character. The breadth of the organ is greater, es- pecially at the fundus, where a depression in the middle line indicates the situation internally of a vertical septum, which more or less com- pletely divides the uterine cavity into two halves, and constitutes the uterus biloGularis. The extent of this septum may vary from a mere ridge to a complete partition, which may even invade the vagina. These several deviations from the normal form of the uterus will influence more or less the function of the organ. Menstruation may, it is true, in a large proportion of cases, be scarcely affected ; and this function will be normally discharged whenever the ovaries are perfect and a normal channel exists. In those rarer cases, however, in which the uterus is rudimentary, there may be perfect ovaries, and atresia either of the cervix or of the vagina, with the result, if a uterine cavity exists, of an accumulation of the discharge, and attendant symptoms of considerable severity. If, on the contrary, there be no cavity, the menstrual molimen may then be relieved by the occurrence of vicarious discharges. As regards the influence exercised by such anomalies upon impregnation, much will depend upon the condition of the vagina, and also of the Fallopian tube, for if either of them are closed, impregnation is of course impossible. If, however, they are IV.] THE OVARIES. 75 open, it is quite possible for impregnation to occur even in a uterus unicornis. 1 Great difficulty and danger may arise, in such cases, during the prog- ress of gestation. In the case, for example, which is referred to in the footnote, death took place from rupture of the sac in the third month, the termination being thus very much what one would expect in a case in which the development of the ovum goes on in the Fallopian tube, instead of in the cavity of the womb. In the cases of the uterus bicornis and bilocularis, either side of the uterus may become separately or alternately the seat of gestation, or twins may be simultaneously developed, one on each side. There is, indeed, no good anatomical ground for absolutely rejecting the doctrine of superfoetation as a possi- bility in such cases. When there is a double vagina, coition usually takes place by one canal, so that successive pregnancies may be looked for on the same side. The effects produced on the act of parturition by such anomalies as have been cited, have probably been exaggerated. Rokitansky has indeed shown that the axis of expulsion may, as in the one-horned variety, be so directed as to place the forces at an obvious disadvantage; but it may be assumed that, if the anomaly has been of such a grade as to admit of complete intra-uterine development, there will not likely be any impediment during delivery, which may not be surmounted by the application of ordinary principles. Cases in which the arrest of development has taken place after birth, are to be placed in a special category. At the ordinary period of puberty, the signs which indicate sexual maturity do not appear, while the uterus is found still to present the characters peculiar to infancy or childhood. In these cases, which are almost certainly pro- ductive of sterile marriages, there is often an absence of the vaginal portion of the cervix ; and the other infantine conditions of the womb may be exhibited in every particular, such as the exaggeration of the forward curve, which, in a smaller degree, we have indicated as the normal adult condition, the persistence, within the cavity, of ruga?, similar to those of the cervix, and the thinness of the parietes. Of the Ovaries. — Projecting on either side from the posterior surface of the broad ligament, and invested with a special fold of its posterior layer, are the important organs within which is elaborated that which the woman contributes to the propagation of her species, analogous therefore in this, as in other respects, to the testicles of the male. They are connected (see Figs. 27, 28, and 29) with the uterus by a special ligament already described, and also through the Fallopian tubes, to one of the fimbriae of which they are permanently adherent. In shape, the ovary is a flattened oval. It varies greatly in size, according to age, and in different individuals of a similar age; but it may be set down as, on an average, about eighty grains in weight, and* an inch and a half in extreme length. From the manner in which it is em- braced by the peritoneum, it is free on two sides, and on the posterior border, and attached to the broad ligament by a kind of mesentery 1 See a remarkable case by Kokitansky, the preparation of which is in the Vienna Museum. (Pathological Anatomy — Syd. Soc, vol. ii, p. 277.) 76 FEMALE ORGANS OF GENERATION. [CHAP. along the anterior border only, where, between the layers, the vessels and nerves enter. The nature of the relation subsisting between the ovary and the peritoneum has of late been a subject of much interest to physiologists, and the observations of Waldeyer 1 certainly now leave no room for doubt that anatomists have been in error in describing the ovary as invested by the peritoneum in the same manner as the other viscera. The structure of the peritoneum proper ceases abruptly at a fold near the hilus, and quite visible to the naked eye. This fold surrounds the ovary in such a way that the greater portion of its free surface consists, not of the peritoneum, but of a special layer, continuous with the peritoneum, presenting, on microscopic examination, a pris- matic epithelium instead of the laminated form which exists in the serous membranes. This prismatic epithelium is intimately connected with the origin of the ova. The ovary attains its greatest size after puberty, and is, up to this period, smooth on the surface. During pregnancy, the position of the organ is completely changed ; but in the unimpregnated condition it will be found lying deeply in the lateral posterior part of the pelvic cavity, covered by the small intestines, and to some extent by the Fallopian tube of the same side. Beneath the outer covering, a dense layer of the stroma, somewhat white in color from a sparseness of bloodvessels, binds the proper structure of the organ together, giving support and protection to it, and to the impor- tant structures which it contains; this is the tunica albuginea. The bulk of the organ beneath this is composed of highly vascular tissue of a pinkish color, which is called the stroma of the ovary. The stroma is composed of a dense fibro-nuclear tissue, through which bloodvessels ramify from the base of the ovary towards its surface. The Graafian Vesicles. — If a longitudinal section is made through a mature and healthy ovary, these vesicles are brought into view, im- bedded in the stroma and varying considerably in size. In number and in situation, they differ greatly according to age. In infants and young children, the ovary is found to be composed, within the tunica albuginea, of two distinct portions, — one internal, corresponding to the stroma in the mature organ, and the other external, of considerable thickness and density. It is in the latter, or peripheral portion alone, that, at this time, the Graafian vesicles are to be found, in enormous numbers, but as yet of small size and in a rudimentary condition. As puberty approaches the distinction between the peripheral and central portion of the stroma becomes gradually less marked. Some of the vesicles enlarge and, according to Schron, retreat in the first instance towards the centre of the ovary. When puberty is attained, a certain number of them enlarge, and those which have attained the greatest size approach the surface. A few of them are from ^th to £th of an inch in diameter, or even more; but the great majority remain much smaller. Their number is also greatly diminished as compared with those existing in the ovaries of children, so that we may assume that a large proportion is absorbed. This number is still, however, very con- siderable, and has been computed by Henle at 36,000 in each ovary of a girl of eighteen. The ova, which are contained within these Graafian 1 Eierstock und Ei. Leipzig, 1870. IV.] STRUCTURE OF GRAAFIAN VESICLE, 77 vesicles, being comparatively small, occupy in the case of the more developed vesicles a small space only, the rest of the vesicle being filled with fluid. Before puberty the ovaries are smooth on the surface, but they subsequently become scarred, wrinkled, and furrowed, in conse- quence of the share which they take — as we shall see immediately — in the phenomena of ovulation. The Graafian vesicle is usually described as consisting of two coats and a granular epithelial layer, three special coverings in all ; but in point of fact, there does not appear to be any distinct membrane lining the Graafian vesicle. This, indeed, is merely ovarian stroma in its finest form ; while, as regards the vascular layer usually described, its existence is more than doubtful, although in its developed state, a net- work of bloodvessels runs near the surface of the vesicle. The Ovum, in the mature condition of the Graafian vesicle, lies near its surface, and is imbedded in the membraria granulosa ; a layer of peculiar nucleated and granular cells, which surrounds the whole of FiCx. 38. Diagram showing the layers of the Graafian vesicle, and the contained ovum. the interior of the vesicle, and is thickened at that part where the ovum is imbedded in it (proligerous disk of V. Baer). This is shown in the accompanying diagram. If the surface of the ovary be punctured, while a mature Graafian vesicle is projecting, and the contents of the latter pressed out, a small spherical body may be observed, if care be taken, covered with granu- lar matter in greater or less quantity. It is more opaque than the medium in which it is suspended, and is remarkably constant in size — being about y-j-o^h of an inch in diameter. It is comprised of the following parts : a. A thick transparent envelope, which was called by Baer, the dis- tinguished discoverer of the ovum in the Mammalia, the Zona pellucida. As this refers only to its appearance, many physiologists prefer to call it the vitelline membrane, or membrane of the yolk. This membrane completely surrounds the ovum, and to all appearance is impervious. It presents at least no distinct aperture or micropyle such as is observed in some animals, and has been by some supposed to exist in the human ovum. b. The Yolk. — The cavity inclosed by the zona pellucida is filled with a substance, which is viscid and faintly granular, and which 78 FEMALE ORGANS OF GENERATION. [CHAP. readily escapes when the sac is ruptured. It can scarcely be described as a fluid, as it retains its spherical form after rupture of the sac, and may, according to Bischoff, be broken into segments. It has no in- vesting membrane other than the zona pellucida. c. The Germinal Vesicle. — In the middle of the yolk, in the earliest stage, and in contact, in adults, with some part of the periphery of the investing membrane, a little vesicle is found, apparently, when seen in the more opaque medium in which it is suspended, quite transparent and colorless. This is the germinal vesicle — first described in the ova of birds by Purkinje, and discovered in the Mammalian ovum by Coste and by Wharton Jones. It is slightly oval, about 7 J()th of an inch in diameter, and surrounded by a very thin membrane. A more careful examination of it when removed from the yolk shows that it is not absolutely transparent, but contains a few scattered granules, and, in addition : d. The Germinal Spot of Wagner, which may be seen close to some point or other of the inner surface of the wall of the germinal vesicle. It is probably formed by the aggregation of cells and granules which give to it a greater opacity than characterizes the contents of the vesicle. It measures about jg'pth to o^pth of an inch. Although it is generally understood that the ovum is always to be found on the side of the vesicle next the surface of the ovary (Fig. 38), recent investigations have shown very clearly that this is by no means universal, and would almost seem to point to the conclusion that the contrary is the rule, and that, in the majority of Graafian vesicles, we are more likely to discover it on the side which lies towards the centre of the organ. The ova begin to be formed at a very early period, and are already to be found in great numbers in the superficial layer of the rudimentary stroma of the human ovary as early as the fourth month of intra-uterine life. But their first origin is even at an earlier period. The germinal vesicle is the part of the ovum first formed, and it appears to arise by involution from the superficial layer of germinal cells. One or more of these cells, becoming larger than the rest, sink into the stroma and soon become surrounded by a single layer of nucleated cells. This constitutes the commencement of the membrana granulosa, and repre- sents therefore the Graafian vesicle. As development proceeds, a small quantity of protoplastic yolk surrounds the germinal vesicle, and the cells of the membrana granulosa increase in number and assume more of the appearance of a cellular lining. The cells accumulate round the simple ovum so as to form the proligerous disk, and a space begins to be apparent between this and the rest of the membrana granulosa, within which the fluid of the vesicle afterwards accumulates. The ovum grows by the increase of the yolk round the germinal vesicle, the protoplasm becoming granular; and, finally, the yolk and germinal vesicle are inclosed by the external firm vesicular membrane, known as the zona pellucida. These, then, are the parts of which the mature ovum, prior to im- pregnation, consists. On the approach of puberty, as has been seen, several Graafian vesicles, each containing an ovum, approach the sur- IV.] PHENOMENA OF OVULATION. 79 face of the ovary. As they increase in size, they form little projections beneath the investing membrane. In those animals where several ova are simultaneously fecundated — as in the sow (Fig. 40) — there may be Fig. 39. Fig. 40. Diagrammatic representation of the ovum, as it Development of Graafian vesicles escapes from the Graafian vesicle. in the sow. observed on the surface of the ovary a number of little cystic growths; but, in the human species, where the fecundation of more than one ovum at a time is exceptional, the Graafian vesicles, as a rule, come to maturity one by one, or in small numbers. The changes which take place during the maturation and discharge of the ova, and which are associated with the "rut" in many of the lower Mammalia, and with menstruation in women, constitute the phenomena of Ovulation. These changes are manifested, not only in the Graafian vesicle, but also in all the component parts of the internal generative system. It has already been observed that the development of the Graafian vesicle is due, in a great measure, to the increase in its fluid contents. While this is taking place, the vascularity is notably increased, not only in the vesicle itself, but in the contiguous portion of the ovary, and, in some degree, throughout the whole of the organ. The walls of the follicles become thickened, except at the part where rupture is about to take place, and a certain amount of blood is said to be effused into the cavity. This has frequently been observed (although even that has been disputed) in the sac of ruptured follicles ; but the researches of Pouchet — whose views are confirmed by Farre — seem to show that an actual sanguineous discharge may take place into the fol- licle, at a period prior to its rupture. According to Pouchet, the effect of this discharge is, mechanically, to force the ovum towards that part of the ovisac which is next the surface, — it being, before this, generally found on the deep or distal side. An increased vascularity is now observed, externally, over the salient portion of the vesicle, and the tissues become, about the centre of the projection, more and more thinned, until, at last, they yield — the ovum then escaping by a process analogous to dehiscence. The rupture takes place in a small spot where the bloodvessels previously are wanting. This is similar to the larger band of non-vascular tissue which exists in the ovicapsules of birds. Towards this non-vascular spot the neighbor- ing vessels converge in considerable numbers, causing the appearance we have just referred to. Assuming the theories above mentioned to be correct, the bursting of the vesicle is due, not merely to an augmen- tation of its fluid contents, but to a thickening of its internal layer, 80 FEMALE ORGANS OF GENERATION. [CHAP. which becomes at the same time irregular in outline and yellowish in color; and also to an effusion of blood, which has been termed the menstruation of the follicle. This evolution of the ovum is accompanied by important changes in various parts besides the ovary. In so far as the uterus is concerned, these changes will come to be considered under menstruation. At present, it need only be observed that the Avhole of the internal genital organs become engorged. The Fallopian tube loses its pale color in- ternally, and often becomes of a violet hue from extreme congestion. This is more marked towards the fimbriated extremity, which com- pletely embraces that portion of the ovary where the mature vesicle is about to give way. The ovum is thus received into the Fallopian tube, but the rupture which admits of the dehiscence does not termi- nate the series of changes of which the ovary is the seat. Before attempting a description of these changes, however, we must consider for a moment the conditions under which rupture of the Graa- fian vesicle occurs, and the laws which determine this rupture. The celebrated experiments of Bischoff, as detailed in his well-known work, 1 have supplied most of the facts upon which, even at the present day, the conclusions of physiologists on this subject are based. From these, and from the corroborative results obtained by subsequent ob- servers, it is clear that ova may, in the Mammalia, as in animals lower in the scale, be discharged from the ovary independently of sexual in- tercourse, or of any kind of influence from the male. 2 In other words, sexual contact or excitement is not, as the earlier observers, down to Barry, believed, the one essential determining cause of the discharge of ova. From experiments on rabbits, which were conducted by Coste, it seems, however, more than probable that sexual congress may pre- cipitate a rupture which, but for the excitement, would have been de- layed. The immediate cause which leads to a rupture is thus somewhat obscure, but Ave recognize the fact that the occurrence is intimately associated with the maturation of the ovum, of which, in women, the periodic menstrual flow is the external manifestation. We have already seen that the internal layer of the Graafian vesicle presents a yellow color previous to its rupture, becomes wavy in out- line, and is very considerably thicker. This change of color has been shown by Farre to be due to the presence of very minute oil-granules, which give to the structure a yellow hue, — hence the name given to the follicle during the period of decline — the corpus luteum. After rupture, a laceration, fissure, or scar, marks, on the surface of the ovary, the spot whence the ovum escaped, and a longitudinal section, made through the ovary in this situation, will generally bring the yellow body into view. At first, its distinguishing characteristics are but faintly shown ; and it is this fact which caused Raciborski to assert that the corpus luteum was not found before rupture. Undoubtedly, however, the first stage of its formation is while the ovum is still within the vesicle; but it is only after rupture that the change in color becomes quite distinct, — a change w r hich Raciborski supposed to be due 1 Beweis der von der Begattung unabhangigen periodischen Reifung und Loslo- sung der Eier, etc. 1844. 2 See Raciborski " De la ponte period i que chez lafemmeetles Mammiferes." 1844. IV.] THE CORPUS LCIEUM. SI to an absorption of coloring matter from the blood-clot which fills the cavity. "Whether it is due in part to this, or wholly to a further de- velopment of oil-granules in the internal layer, as Coste supposed, the result is the yellow tint, which may be recognized from without, or. more distinctly, on sectiou. If the laceration has produced an opening of sufficient size, the clot which occupies the cavity may escape along with the ovum; but, if not, it is retained and absorbed. The folding of the internal layer now becomes much more distinct, so that the internal surface of the vesicle resembles cerebral convolutions on a minute scale. According to Coste, this plication is due in great measure to retraction of the external coat, but this does not seem by any means clear, seeing that the convolutions become quite as distinct in those cases where the diameter of the whole vesicle is not diminished. It is much more likely that the plication is mainly due to the rapid increase in the cells of the membrane, which, being confined within a limited space, is thus necessarily thrown into folds. In every case, the cavity of the vesicle becomes rapidly encroached upon, the furrows between Ovary dissected, to show the structure of the Graafian vesicle at various stages. (Coste.) the convolutions become deeper, and the result is that the follicle now presents, in a section, a stellated appearance, which is more or less marked according to the stage at which the corpus luteum has arrived. The various changes above alluded to are shown in Fig. 41. taken from (Teste's atlas, which represents an actual dissection, made at the Morgue, of the ovary of a young woman who had committed suicide towards 82 FEMALE ORGANS OF GENERATION. [CHAP. the end of a menstrual period. It must here be noted, however, that the most recent observations have failed to demonstrate the layers of the Graafian vesicle which Coste has so distinctly indicated. The ovary is partly dissected, to show the situation of the ova; and also the structure of the Graafian vesicles, and the changes which they undergo after rupture. Most of the vesicles are turgid, tending to pro- trude, and indicated by the network of vessels on their walls. Three of them are open. 1. The vesicle to the left in the figure is intended to demonstrate the following peculiarities: g g. The granular membrane, which covers the whole internal surface of the Graafian vesicle. A thickened portion of this — granular disk — showing: o. The Ovum surrounded by the cells of the disk, and situated, as is usual, im- mediately before rupture, on the side next the peritoneum. i i. Internal layer of the Graafian vesicle, showing a rich vascular network, not only on the flaps which are turned back, but also in the interior of the vesicle, through the granular membrane. e e. External (vascular) layer, vascular like the former. 2. The open Graafian vesicle in the centre of the figure has broken spontaneously at the point v, and has allowed its ovum to escape. The nipple-shaped part of the granular membrane, in which the ovum was imbedded, has escaped along with it. g. Layer of granular membrane, which has not been dragged out with the ovum. i. Internal layer of the Graafian vesicle, forming numerous folds, which are the earliest of the modifications through which this layer passes in the formation of the Corpus Luteum. e. External layer of the Graafian vesicle, retracted (sic Coste) on the former. 3. The third Graafian vesicle, to the right, has been artificially pierced to show how the ovum, while escaping, drags with it that portion of the granular mem- brane in which it is lodged. g. Portion of the granular membrane, escaping by the opening made in the Graafian vesicle. ce. Ovum lodged in the thickened nipple-like projection of this membrane. Coste denies the presence, as a Fig. 42. Structure of the corpus luteum. (Coste.) rule, of a blood-clot within the Graafian vesicle. He asserts that the vesicle, after rupture, becomes filled with a gelatinous matter, which is slightly tinged with the coloring matter of the blood. This he shows in Fig. 42, where the ovary is divided in its whole length to exhibit the organization of the corpus luteum. The prep- aration was taken from a woman, the mother of several children, who died from poison a few days after menstruation. The body was exhumed and examined a week after death. No ovum was found in the uterus, nor in the Fallo- pian tube. An open corpus lu- teum, of considerable size, is shown in the lower part of the figure. a. Internal laver of the Graafian IV.] STRUCTURE OF CORPUS LUTEUM. 83 vesicle, plicated and having commenced that hypertrophy which con- verts it into corpus luteum. b. Plastic semitransparent matter, which occupies the centre of the corpus luteum, adheres intimately to the internal surface of the con- volutions, and moulds itself upon them. To the right, this matter is left in its place ; on the left it has been detached, to show the subjacent convolutions and the impression which they leave upon it. c. An old corpus luteum, from a preceding menstruation, probably the one before last. Graafian vesicles — some intact, others open, and in various stages of development, are seen in other parts of the ovary. The description given, up to this point, applies to all corpora lutea, whether associated with pregnancy or not. It is therefore scarcely necessary to add that Haller was in error when he stated that " the corpus luteum is the effect of pregnancy alone. 77 The demonstration of this error caused many hastily to assume that the corpus luteum was, under no circumstances, a sign of pregnancy, and was, in conse- quence, of no medico-legal value — an unfortunate mistake, which has been productive of much confusion, as there certainly are points of difference which enable us, with care, to distinguish between the two varieties. The corpus luteum which is found when there has been no impreg- nation, runs something like the following course from the point at which we left it. It shrinks rapidly, the retractility of the outer coat being apparently the chief agent in its contraction. The contiguous surfaces of the convolutions become pressed together, and their free surfaces gradually approach across the cavity, so as rapidly to cause its obliteration. The vascularity of the vesicle, and of the stroma of the ovary, becomes notably diminished, the ovisac loses its yellow color, and becomes white — all these changes occurring in about twenty-five or thirty days, so that, on the approach of another menstrual period, the cavity is reduced to a comparatively small size. At this stage, its appearance, as represented in Fig. 43, a, is very characteristic, the rays which proceed outwards from the central cavity showing the point of junction of the convolutions. Several other vesicles are shown, of the ordinary size before enlargement. From this stage, the stellate re- mains of the vesicles gradually diminish in size, and retreat towards the centre of the stroma, to give place to others, until at last they are obliterated. Sometimes, they soften so rapidly, that they are com- pletely reabsorbed before the folds of the internal layer have actually come in contact or contracted adhesions. Widely different is the state of matters where the ovum has been impregnated. In this case, the functional activity of the uterus is, in a measure, shared by the ovaries, and manifests itself in an increased vascularity, which, instead of disappearing, as at the end of a menstrual period, is maintained, more or less, during the whole course of the pregnancy. It is, probably, in consequence of this, that the corpus luteum of pregnancy goes through a series of transformations, so much more elaborate, and extending over a period the duration of which is so much longer. Taking the duration of an unimpregnated follicle as 84 FEMALE ORGANS OE GENERATION. [CHAP, about two months to complete obliteration, the corpus luteum which accompanies pregnancy may be said to last usually for thirteen or fourteen months, while traces of it may be found at a still later period. Such a history involves the idea of special structure and modified development, and this a study of the facts amply corroborates. When pregnancy succeeds or accompanies the phenomena of ovulation, the earlier changes are the same as those already described; but instead of softening and rapidly shrinking, as in the former case, the inner coat, or ovisac, continues to develop in thickness, and deepens in color, in Fig. 43. Fig. 44. The corpus luteum of simple ovulation. Corpus luteum in the third month of pregnancy. (Montgomery.) consequence of an increase in the number of oil-granules in its sub- stance. There does not seem, in the first instance at least, to be any contraction whatever of the external membrane. On the contrary, there is some reason to believe that, at this stage, it often yields, so as to admit of an increase in the entire diameter of the vesicle, and, in- deed, if we admit Coste's description to be correct, when he describes the corpus luteum of pregnancy to be " as large as the ovary itself," this can only be accounted for in the manner described. The size of the ruptured follicle varies considerably, but it occupies, usually, during the first four months, about a fourth, a third, or a half of the entire ovary. During the period immediately succeeding impregnation, rapid hypertrophy of the inner coat goes on, and it becomes folded together into convolutions as before. The material being abundantly supplied, while the development still continues, causes the convolutions to be firmly pressed together, while their free surface encroaches upon the cavity. At the end of two months, the condensation of the hyper- trophied tissue of the ovisac will be found to have imparted to the follicle a considerable amount of solidity, which is quite obvious when it is pressed by the finger. Bloodvessels run through it, from the cir- cumference towards the centre, marking, probably, the situation of the original folds. These latter are no longer distinct, and are so com- pressed laterally that the layer has now the appearance of a very thick yellow coat surrounding the diminished cavity, which is up to this time, according to Montgomery, usually circular in form, as shown in IV.] THE CORPUS LUTEUM, 85 Fig. 44. The cavity here represented is, however, exceptional, and subject to much variety. The blood-clot which originally occupied the cavity, or, if we choose to adopt the view of Coste, the tinged lymph which is effused after rupture, undergoes certain metamorphoses, which ultimately result in the formation of a milk-white coat which lines the cavity, taking the place, as it were, of the original granular membrane. This membrane, which is also shown in Fig. 44, is fibrous in structure, and extremely tough. Occasionally, the cavity is obliterated at the fourth month, but generally it will still be found perfectly distinct, although much reduced in size, up to the sixth month of pregnancy (Fig. 45). The walls continue gradually to approach nearer to each other, the white lining membrane becomes thinner, and, folded into plaits, which, radiating outwards, are seen to intermingle with the yellow color of the ovisac. The outer boundary of the vesicle now becomes irregular in outline, Fig. 45. Corpus luteuni at the sixth month of preg- nancy. (Montgomery.) Corpus luteum at the period of delivery. and complete obliteration of the cavity ensues, a white stellated cicatrix in the midst of the yellow mass marking where its walls came into contact. This is shown in Fig. 46, the original drawing of which was taken by Montgomery from a woman who had died of inflammation of the uterus two days after mature delivery. Up to this time, and often for some weeks afterwards, numerous vessels radiate through the corpus luteum, as may be proved by injection. This vascularity is now markedly diminished, while, at the same time, the characteristic yellow color becomes fainter in hue. It is often not till four or five months have elapsed that all trace of the corpus luteum has disap- peared, a trace of the tough white membrane being then, it may be, still indicated by a very faint star-like scar in the stroma of the ovary. As the facts above set forth are of some medico-legal, as well as obstetric importance, they may be briefly summarized as follows : 86 FEMALE ORQANS OF GENERATION. [CHAP. What is called the corpus luteura is due to a deposit of yellow fatty matter in, and hypertrophy of, the internal layer of the Graafian vesicle (ovisac). The formation of a corpus luteum always succeeds the rupture of a Graafian vesicle. Up to a certain point the changes in the Graafian vesicle are uniform, and have no relation to pregnancy. The corpus luteum of pregnancy may, however, be distinguished in its subsequent course, by its higher development and longer duration, its hardness, its vascularity, and, at a later stage, by the formation of the white lining membrane, and large central stellate cicatrix. The presence in the ovary of a corpus luteum is no evidence of preg- nancy, unless the characteristics last indicated are distinct and une- quivocal — under which circumstances it is a certain sign. With reference to the above conclusions, it may be remarked that much confusion has arisen from the employment loosely of the terms "true" and "false," as applied to the corpus luteum, in so far as they are assumed to imply a distinction, which proves or disproves the occurrence of pregnancy. " There is as little reason," says Farre, with justifiable emphasis, " for the use of the last term as there would be for denominating a child a false man. . . . These terms actually represent the same body, only in different stages of growth or decay." During the whole of the childbearing period of a woman's life, the ripening and dehiscence of the Graafian vesicles are of periodic occurrence. In those animals in which plural births are the rule, several vesicles ripen and discharge their contents at, or near, the same time ; but in man this is exceptional, and we thus find that one vesicle only, as a rule, ripens at a time, bursts, discharges its contents, and rapidly shrinks as it retires towards the centre of the ovary ; to give place in their turn, in a normal condition of the parts, to a constant succession of vesicles, which, one by one, run a similar course after discharging their ova. There is every reason to believe, further, that during preg- nancy and suckling, while the uterine functions are in abeyance, those also of the ovary are temporarily arrested, in so far as the development of new Graafian vesicles is concerned, — the whole generative force being, as it were, turned into other channels. The numerous lacerations which, in consequence of repeated ruptures, take place on the surface of the ovary, leave, in the process of healing, corresponding cicatrices. On this account the smoothness of surface is soon lost, and it becomes more and more fissured and wrinkled, until, towards the end of the childbearing epoch in a woman's life, the ovary is so irregular on the surface, as to warrant the comparison which Raciborski has instituted between it and the kernel of a peach. After this, the organ becomes atrophied, and, like the uterus and other parts, is restored, in some measure, to the form which it presented in early life. V.] MENSTRUATION AND CONCEPTION. 87 CHAPTEE V. MENSTRUATION AND CONCEPTION. THE " EUT " OF MAMMALIA: ANALOGY BETWEEN THIS AND MENSTRUATION — THE FIRST MENSTRUAL PERIOD: STATISTICS OF DURATION OF A "PERIOD." — QUAN- TITY OF THE DISCHARGE — MENSTRUATION A HEMORRHAGE : NON-COAGULA- BILITY OF — SOURCE OF THE MENSES : VARIOUS THEORIES REGARDING : IS FROM THE MUCOUS MEMBRANE OF THE CAVITY — POUCHET'S THEORY EXAMINED; IS THE MUCOUS MEMBRANE SHED? — VIEWS OF KOLLIKER, COSTE, ETC. — DURATION OF CHILDBEARING EPOCH — CAUSE OF MENSTRUATION — CONCEPTION — COMPOSI-^ TION OF THE SEMEN — SPERMATOZOA AND THEIR DEVELOPMENT — "SPERM- CELLS " — THE FUNCTION OF THE GERMINAL VESICLE ; " GERM-CELLS " — HOW DOES THE SEMEN REACH THE OVUM ? There is, in the animal kingdom generally, a certain periodicity in the phenomena which attend the maturation of the Ovum. In the Mammalia, there always is a period of excitement, in which the whole generative apparatus more or less participates ; succeeded by a period of rest, of longer or shorter duration, according to the group or species, during which the organs involved are in a state of complete or com- parative quiescence. The first marks the period at which the ovum is ready for impregnation ; during the latter sexual congress, is, as a rule ineffectual. This term of excitement, which is accompanied by general and local symptoms to be noticed presently, is called, in mammals lower in the scale than man, the rut or oestrus. There is not the slightest doubt that, in those animals, the escape of the ova from the ovary, and their passage down the Fallopian tube, are facts which coincide with the oestrus. The female then manifests an instinctive desire for copulation, and is generally said to be at this time " in season " or " in heat.' 7 The pudendum is congested and swollen, and the glands in this region pour out an abundant secretion, which, by its odor, attracts the male. This secretion, unless in those animals which come nearest to man in the scale, is very seldom even tinged with blood. In some cases, as was demonstrated by Bischoff in the case of the roe, the rut occurs only at intervals of a year, about the month of August. It is only at this period that the ovaries of the female contain ripe ova; and, what is of even higher physiological interest, the semen of the male is elaborated then and then only, so that impregnation is doubly impossible, save with a view to the birth of the young at that time of the year when they may be most easily reared. But, in many animals, the maturation and dehiscence of the ova occur with much greater frequency, and it is probable that food, domestication, and careful tending, may modify the return of those periods. 88 MENSTRUATION AND CONCEPTION. [CHAP. In women, during the period of ovulation, there are, as has already been shown, certain essential phenomena which are, so far, almost identical with what we observe in other mammalia. But there is here a special phenomenon superadded, which is in fact the external mani- festation of what we know to be taking place internally. This consists in a discharge from the uterus of nearly pure blood, which lasts usually for several days. It is called the " catamenial " or " menstrual " dis- charge, as it occurs very constantly at intervals of a month ; the occur- rence being, in its course, usually designated as menstruation. A very warm discussion has been maintained for many years as to whether the " rut " and " menstruation " are to be held as analogous. Up to a certain point, the analogy is admitted by all ; but it must be conceded that, between the two, distinctions and even contrasts are found, on careful examination, to arise, which seem to challenge the truth of the assertion which many have made, that the phenomena are •physiologically identical. Without expressing any confident opinion as to this quwstio vexata, we may here mention the chief points, in ad- dition to the sanguineous discharge, in which they differ. Impregna- tion takes place during the excitement of the rut, while as a general rule it occurs in women about a week after menstruation, during the period of rest. Again, there succeeds to the rut a period of inappe- tence, when not only does the female refuse the male, but in some cases no semen is, as we have seen, secreted ; in the human species there is, strictly speaking, no period of inappetence, not even excepting the period of the menstrual discharge, so that at any time impregnation may occur. Great as these differences undoubtedly are, and even if we admit that they destroy the identity of the acts, they are scarcely suffi- cient to warrant us in rejecting the analogy ; for, although the subject is still obscure, a more accurate knowledge of the time occupied by the descent of the human ovum may show that the above points of con- trast are more apparent than real. Menstruation is familiarly termed by women the " courses," " monthly illness/ 7 or " period." It is not to be looked upon as an isolated act, but as one of the important series of phenomena which occur during ovulation ; and as such it requires special and careful attention. Its first appearance is associated with the other signs of puberty. The approach of this is indicated by an alteration in the form of the pelvis, and a consequent change in figure and gait ; by the growth of hair on the pubes, the rapid development of the mammae, the greater projection of the nipple, and the deeper color of the areola. These physical modifications are generally associated with very characteristic moral changes. A frank romping manner gives place to one more timid and gentle, and the loud voice and ringing laughter of childhood is replaced by subdued tones and bashful reserve. A Graafian vesicle now for the first time comes to maturity, and projects on the surface of the ovary, which is embraced by the fimbriae of the Fallopian tube, while the whole of the organs, including the uterus, become highly congested. According to Boerhaave, the first menstruation is accompanied with a certain amount of fever, as the result of the excitement of the genital organs. The girl complains of lassitude, hypogastric fulness, lumbar V.] STATISTICS OF MENSTRUATION. 89 and sacral pains, slight itching and tumefaction of the external geni- tals, and a painful swelling of the mammae. Not unfrequently, hysteria, chorea, and other nervous disorders, manifest themselves, — generally in a mild form. After a few days, a mucous discharge, more or less abundant, is observed; this becomes tinged with blood, and after a time is found to be almost pure blood, to be again replaced by a tinted, and finally by a clear discharge, closely resembling that which at first showed itself. The previous symptoms disappear with the menses, which may have lasted a week ; and she is restored to perfect health, but with an indescribable something in manner and appearance which marks the transition into womanhood. Such symptoms as are above detailed, on the authority of Boerhaave, as accompanying a first men- struation, are generally slight in degree, the discharge often appearing during sleep, or at any other time, without anything whatever of the nature of premonitory symptoms. Very often, for a period or two, some of the same symptoms are experienced, at intervals of a month, without any flow of blood. These indicate preliminary or abortive attempts on the part of nature, — the Graafian vesicles being probably, as yet, not perfectly mature ; but there is little reason to doubt, that the first maturation of a vesicle is, as a rule, coincident with the first menstrual discharge. The initiation of this period of a woman's life is believed to be hastened by hot climates, by residence in towns, and the habits which are there contracted, and by constitutional vigor ; while cold tempera- tures, country residence, and a feeble and delicate temperament, retard the act. In a certain number of cases, menstruation is postponed to a period of life much more advanced than usual. We read, for example, of a case in which a woman who had married at twenty-seven, men- struated for the first time two months after her eighth labor ; and of another who had no discharge until after her second marriage, at the age of forty. Numerous cases of premature menstruation are also on record, where menstruation has actually appeared during infancy, and where the external appearances and sexual desires of maturity have been manifested at a very early age. In a case cited by Cams, a child menstruated at the age of two years, became pregnant at eight, and lived to an advanced age. Such cases are, of course, extremely rare ; but of more frequent occurrence are those instances in which women become pregnant without ever having menstruated ; while it is by no means an uncommon thing for a woman who is nursing, to become pregnant again before the menses have returned, such facts indicating, as Cazeaux observes, that menstruation plays a secondary part in the phenomena of ovulation. Putting such exceptional cases aside, as irregular and abnormal, we at once recognize the fact, that the time of a first menstruation varies greatly, according to climate, constitution, and the kind of life which is led. In so far as climate is concerned, the influence exercised by it, while quite marked, is by no means so considerable as was once be- lieved, and may be represented by a period of three years at the fur- thest between the extremes, which we may suppose to exist in the Hindoo and the Esquimaux. At one time, ideas were entertained on 90 MENSTRUATION AND CONCEPTION. [CHAP. this subject which more correct observation has shown to be absurd, and to no one are we more indebted than to Mr. Roberton, of Man- chester, for clearing away the errors which were long promulgated on these points. The following table, which shows the period of the first menstruation in 8983 cases, is the result of a very careful analysis of the most reliable statistics which have been published in Europe on this subject. Some idea is here given of the variation in the different countries of Europe, and shows the very small proportion of cases in which men- struation first appears under ten or over twenty-two years. The period, as will be observed, varies very considerably, about the age of sixteen being the time at which it most frequently shows itself in this country. At any age, however, between twelve and twenty, the function may be established, without any peculiarity whatever in the attendant symp- toms or deterioration of the general health ; but if beyond these limits, it may be looked upon as exceptional and irregular, although even then, as in the cases alluded to, the health may in no way suffer. Age. England, j France. Germany. Norway. Russia. Total. Roberton, Brierre de Lee, White- Boismont, head, and Raciborski, Murphy. Bouchacourt. Osiander. Faye. Lebrun. Under 10, 10 to 13, 11 " 12, 12 " 13, 13 " 14, 14 " 15, 15 " 16, 16 " 17, 17 " 18, 18 " 19, 19 " 20, 20 " 21, 21 " 22, Over 22, 14 64 103 278 595 1034 1178 1307 714 531 213 104 18 17 16 41 138 209 258 355 411 349 287 190 102 66 31 23 3 8 21 32 24 11 18 10 8 1 1 4 4 13 14 20 13 13 6 8 3 o 1 15 27 35 13 6 2 1 30 105 241 494 865 1424 1650 1727 1060 765 337 188 54 43 Total, 6170 2476 137 100 1.00 8983 Once established, the menses should return with periodic regularity during the whole childbearing epoch. The recurrence of the discharge is always attended with local, and generally with constitutional, symp- toms. The latter are identical with those which accompany the first menstruation, only less in degree, and constitute what has been termed the menstrual molimen. The only circumstances which normally arrest this function of the uterus are the occurrence of pregnancy and lacta- tion, during which the ovarian and uterine functions are generally in complete abeyance. If, under other circumstances, it should disap- pear during the childbearing epoch, it is regarded as an indication of some morbid condition, usually constitutional, and which declares itself V.] QUANTITY OF THE DISCHARGE. 91 as a rule by the presence of other symptoms. It may last from one to eight days, eight being, according to Brierre de Boismont, the most common, and, strange to say, seven the least so. The following is, ac- cording to the same observer, the duration in days arranged in the order of frequency in which each day is selected : 8 : 3 : 4 : 2 : 5 : 1 : 6 : 10 : 7. 1 The catamenial period and interval together occupy a period of a month of four weeks, or twenty-eight days. This is the rhythm of the act in such a large proportion of cases, that we may set it down as the rule ; but it is a rule to which we find constant exceptions, a few days more or less than the limit here mentioned being of constant occurrence, much greater irregularities, indeed, being quite compatible with perfect health. It is by no means rare to find a woman who menstruates once in six weeks or once in a fortnight, without any inconvenience what- ever. In all cases, it is the continuance of the flow which mainly de- termines the duration of the interval or intermenstrual period. In some, and under the influence of morbid conditions, a leucorrhoeal dis- charge takes the place of the ordinary menstrual flow ; and, in others, the molimen is relieved by a discharge of a hemorrhagic nature from some other surface. Both of these conditions, although essentially pathological, are, nevertheless, in not a few instances, beneficial in their action. The amount of the discharge is very variable even in the same woman, and very different opinions have been formed as to what is to be considered a normal quantity over the whole period. The obvious difficulties in the way of such an investigation have hitherto prevented anything like a reliable estimate. That of Hippocrates, which we have on the authority of Galen, assumes eighteen ounces to be lost at each period, but this has not been confirmed, even proximately, by any modern observer. Meigs put it down at four to six ounces, Dehaen at three to five, and Farre at two to three ; and there can be no doubt that these figures give a more accurate idea, and that Farre is probably correct when he says " that a discharge, amounting to six or more ounces in the aggregate, will generally produce for the time sensible effects upon the constitution, such as general pallor, and some feeble- ness of the muscular system. " In regard to the nature and influence of the menstrual discharge, very incorrect and even fabulous opinions were entertained. Pliny assures us that the presence of a menstruating woman blights vegeta- tion, turns wine sour, and produces a number of other and similar effects ; and in some districts, even at the present day, traces of this superstition are to be found. The peculiar odor which was described by De Graaf, and which has been compared by some French physiol- ogists to that of the marigold, is a very usual characteristic of the discharge ; but it is scarcely necessary to add that, in the absence of any morbid condition, neither this nor any other quality of the dis- 1 De la Menstruation : par A. Brierre de Boismont. Paris, 1842. 92 MENSTRUATION AND CONCEPTION. [CHAP. charge can produce deleterious results. During the height of the period, it is composed, as the researches of Donne, Pouchet, Letheby, and others have abundantly proved, almost entirely of pure blood, mixed with a certain quantity of mucus. During the periods of in- vasion and decline the mucus predominates, the color being in direct proportion to the number of blood-corpuscles, which are seen by the microscope, mixed with epithelial scales and with mucous corpuscles from the cervix. There is one striking peculiarity which serves to distinguish this from ordinary hemorrhagic discharges — its want of coagulability. This was at one time supposed to be of itself sufficient evidence that it was not blood, or was blood deprived of its fibrin ; but no doubt now re- mains that the arrest of coagulation depends upon the mixture of the acid secretion of the vagina with the still fluid blood as it escapes from the os, which not only maintains the fibrin in solution, but also renders it difficult of chemical detection. When the quantity is excessive, con- stituting the affection known as menorrhagia, nothing is more common than to find clots discharged, the blood being then so far in excess as to neutralize the acid in the vagina. And, besides, it has been proved that if the blood be collected as it escapes from the os, and before it mixes with the mucus, it is coagulable and alkaline in reaction. These facts suffice to prove that the discharge is a hemorrhage. Source of the Menstrual Discharge. — There are few subjects in phys- iology which have given rise to more discussion than this. Some ob- servers have seen blood oozing from the surface of the vaginal mucous membrane, while others have traced it to the os and cervix uteri ; and on isolated observations such as these, theories on the subject have been founded. Admitting the facts upon which these theories have an unsubstantial basis, we recognize in them nothing more than ex- amples of vicarious menstruation, a term which has been applied to those cases in which the menstrual molimen is relieved by a discharge through an unwonted channel. That the menstrual discharge has its true source in the mucous membrane wdiich lines the cavity of the uterus is a fact which admits of no doubt, and has been proved to demonstration, by examination of the uteri of women who have died during a period ; by accumulation of blood within the cavity in cases of atresia of the cervix or of the vagina; and, finally, by the examina- tion of cases of chronic inversion of the uterus, which offer peculiar facilities for the study of the subject. In our view of ovulation, those of the essential phenomena of the process which have their seat in the uterus and its lining membrane, were left for consideration at this place. In point of fact, we may assume that menstruation itself is essentially one of these phenomena, which are mutually dependent on each other. Along with the enlarge- ment of the ovary and Fallopian tubes already described, a very con- siderable enlargement, involving an increase in weight, takes place in the uterus. Its vascular apparatus becomes developed and injected in an unusual degree. This is especially marked in the case of the mucous membrane, on the surface of which, under the epithelium, the ▼••] SOURCE OF THE MENSTRUAL DISCHARGE. 93 vascular network already described becomes very distinct where the vessels surround the orifices of the utricular glands. The glands them- selves are also visibly enlarged, Tumefaction of the uterine mucous membrane during menstruation. (After Coste.) and any difficulty which may arise in demonstrating them while the uterus is at rest, now no longer exists. The mem- brane becomes increased in thickness, its color is deepened, and the temperature of the whole womb is raised. The result of these changes is that the membrane becomes hyper- trophied to such an extent that it is thrown into convolutions, which are soft, pressed together, and project into the cavity so as to fill it completely, its walls being thus no longer smooth but wrinkled. (Fig. 47.) M. Coste, whose conclusions are based upon no inconsiderable number of such observations, says that, save as a pathological product, no such pseudo-membranous exudation exists, as has been described by physiologists of repute. A closer examination of the surface shows that, at this period, it is dotted over with minute specks, which a low magnifying power proves to be small drops of blood occupying the orifices of the utricular glands, from which they may be dislodged by gentle compression of the walls. This, however, does not determine the ultimate source of the haemor- rhagic flow, and it is around this part of the subject that the greatest difficulties have arisen. That it is not a secretion, in the proper acceptation of the term, as was once believed, is a postulate which the analysis of the discharge enables us to affirm. We need not therefore address ourselves to the refutation of an exploded theory. The view entertained by Coste, is that it is a transudation through the walls of capillary vessels, chiefly venous, or in other words (if we do not misunderstand him) that a con- siderable haemorrhage takes place in this manner, without any breach whatever in the walls even of the smallest vessels, a conclusion which all physiological analogy forbids us to accept. That there may be permanent vascular orifices through which the blood escapes during the menstrual period is an idea which has found favor in the eyes of some eminent physiologists, among others Dr. Far re. Nor is this so fanciful a view as one might be disposed at first to consider it. If there are permanent orifices, it may indeed be asked, why is there not continuous haemorrhage? And in reply, it may be assumed, hypothetically of course, that these orifices are, during the intermenstrual period, closed by the contractility of the tissues which surround them ; but that the increased vascularity, tumefaction, and relaxation of all these parts, 94 MENSTRUATION AND DISCHARGE. [CHAP. which coincide so constantly with the other phenomena of ovulation, admit of a welling forth of pure blood through apertures which now, under the special circumstances, become patent, and which, the apogee of the period having passed, forthwith commence to close, to open afresh on the approach of the next menstruation. The theory, however, which perhaps of all others has attracted in recent times the greatest amount of attention, is that which is associated chiefly with the name of M. Pouchet, and to this theory some of the ablest of our English writers have given their adhesion. Pouchet — if we mistake not — supposed that the whole, or at least the greater part of the mucous membrane (not the epithelium merely) is shed at each catamenial period ; and that its separation from the subjacent tissues involves the rupture of vessels, whence the menstrual flow. This, however, would involve a very different appearance of the internal surface of the uterus, from that which has been above described as occurring at this time, and which we believe to be substantially correct. A separation of a membrane so thick and so important Avould, in fact, be capable of obvious anatomical demonstration ; and if it could be so demonstrated, we would at once have, in the trunks of the vessels which must of necessity be ruptured, the source, clear and unequivocal, which we are endeavoring to trace. The separation of the mucous membrane of the uterus, under the name of decidua, which occurs in women at the moment of delivery ; and the occasional occurrence of what is known as membranous dysmenorrhea, when, in certain morbid conditions, the whole membrane is actually exfoliated, and shed either piecemeal or entire, are facts which have seemed to M. Pouchet sufficient to establish an analogy, on which, mainly, his theory is based. The mucous membrane, he says, is deciduous not merely at the termination of pregnancy, or as a consequence of an exceptional morbid action, but at each menstrual period. No such separation takes place in the lower animals, and in this distinction we find revealed at once the source of the menstrual discharge, and the reason why, in the human species, haemorrhage is superadded to the ordinary phenomena of " rut." In- genious as this theory may be, and interesting as the facts undoubtedly are which its promoter has brought to bear upon it, it is one, we think, which requires closer investigation. If M. Pouchet could show us the exfoliated membrane, and the raw, bleeding surface which its removal necessarily involves, as he might do in membranous dysmenorrhea, or in women who have died shortly after delivery, his theory would be established, and the question for- ever set at rest. But in this he has scarcely succeeded. Opportuni- ties of examining the bodies of women who die during a menstrual period are, no doubt, rare ; but, a sufficient number of such examina- tions have been made by Coste, and, more recently, by Kundrat and Engelman, to show what is the usual condition of the parts. In a certain number of cases, no doubt, something approaching to complete exfoliation does occur, but even Pouchet himself is forced to admit that these cases are exceptional. His ultimate conclusion seems to be that the membrane desquamates, not during menstruation, but in the inter- val. This, however, abandons all the advantage which he gained from V.] CAUSE OF MENSTRUATION. 95 the analogy which he so ingeniously established. For there can be no comparison between a desquamation occurring when the functional activity of the womb is in abeyance, and one which is uniformly asso- ciated with its highest functions ; although an analogy might fairly enough have been traced between the birth of the decidua, in the final act of parturition, and the shedding of the same membrane in connec- tion with a process which is held to be, up to a certain point, prepara- tory to the reception and development of the ovum. The separation of the membrane from the subjacent structures would certainly, if occurring during menstruation, account satisfactorily for the discharge; but, even if it were established that an intermenstrual exfoliation did occur, this would, in no sense whatever, account for the periodical phenomena of menstruation. Dr. Tyler Smith states, that, having had several opportunities of examining the uteri of women who had died during menstruation, he found that the appearances presented were similar to those which are observed after abortion. "In each of those cases," he says, " I found the mucous membrane of the body of the uterus either in a state of dissolution, or entirely wanting." In one case — of which he gives a drawing in his "Manual" — he found that " in the cervical canal the mucous membrane was perfect, but at the os uteri internum it ceased as abruptly as though it had been dis- sected away with a knife above this point. Blood was oozing at numerous points, from broken vessels in the submucous tissue." In a microscopic examination of this case, in which he was assisted by Dr. Handfield Jones, no traces of the epithelium or utricular glands could be found. Now, if Dr. Tyler Smith founds his belief in the exfoliation theory, on such cases as this, he goes much further than Pouchet him- self, in attempting to prove, w r hat that physiologist does not, that the separation of the membrane occurs during menstruation. Speaking with that respect for his views to which such an eminent observer is entitled, we are inclined to assume that Dr. Tyler Smith w r as mistaken, and that the case was either a very exceptional one, or that he mistook shedding of the epithelium for separation of the entire membrane. We believe that, in all probability, the views of Kolliker, which have been recently, in some degree, confirmed by Robin, point to a more correct conclusion than any of the theories above stated. These distinguished histologists believe, with Coste, that the mucous mem- brane becomes thickened during menstruation. They hold, however, that the blood escapes from ruptured superficial capillaries, the epithe- lium covering the mucous membrane of the body being, in great part, thrown off. The interesting observations of Robin, as to the structure of the utricular glands, make it more than likely that -a considerable portion of the discharge comes from these ; but that it comes from the surface of the membrane as well, and probably, to a trifling extent, from that of the Fallopian tubes, we may consider as certain. There can be little doubt, however, that a certain change does take place in the epithelium during menstruation. Independent observers have shown, for example, that, as during pregnancy, so also at this time, the epithelium is deprived of its vibratile cilia. Farre has occasionally observed, in an injected uterus, that the capillary vessels, which form 96 MENSTRUATION AND CONCEPTION. [CHAP. so fine a network upon its inner surface, are " denuded, and hanging forth in detached loops." Such observations, taken along with the fact that epithelial cells, and a certain amount of debris, are found mingled with the catamenial discharge, suffice, we think, to prove that, during menstruation, the flow of blood is from the mucous membrane of the cavity, and that certain changes in, and probable loss of the epithelium, are associated with the flow. The view above expressed has received recent confirmation from the interesting observations of Kundrat, above referred to. As the result of microscopic researches in the case of women who were either men- struating or pregnant at the time of their death, he concludes that a few days before the menstrual flow is established, a proliferation of the cells of the interglandular tissue takes place, by which that portion of the mucous membrane which lies nearest the cavity becomes infiltrated with newly formed round cells. When the capillary vessels rupture, these cells have already passed through a stage of cloudy swelling and fatty degeneration, and it is this superficial portion of the mucous mem- brane which is thrown off during the continuance of the discharge, and for some days after its cessation. To this extent, then, we hold it to be established that the mucous membrane of the uterus is shed at each menstrual period ; and that Pouchet's theory, as corrected by more modern research, is not so wide of the truth as it at first appears. The menstrual, or childbearing epoch of a woman's life ranges on an average from twenty-five to thirty years, ceasing most frequently between the ages of forty-five and fifty. So long as the woman enjoys perfect health, the appearance of the discharge should be at regular in- tervals, of which the normal duration is twenty-eight days. Some women, however, as is well known, menstruate every three or every six weeks, and we are only justified, practically, in looking upon such cases as abnormal, when the general symptoms are such as to call for interference. Irregularities occur, too, as we have already seen, fre- quently enough during the first months of menstruation; and we find also that, as the catamenial climacteric or change of life approaches, the cessation of the menstrual function does not occur abruptly, but after marked premonitory symptoms. At this period of her life, a woman becomes subject to many hysterical and other minor ailments, from which she may previously have enjoyed an entire immunity. A period may, possibly for the first time, pass without discharge. On the next occasion, an increased quantity seems as it were to compensate for the omission which nature had made. Intervals of longer duration may now succeed, intervals which bear no relation to former menstrual epochs, until after a certain number of fitful and capricious efforts on the part of the uterus to relieve itself as before, the catamenia finally cease ; the uterus becomes less in size, and the ovaries shrink so rapidly, that they become wrinkled on their external surface, so as to resemble, as Raciborski says, the kernel of a peach. The only normal exceptions to regular menstruation are pregnancy and lactation ; but even these are by no means regular in their occurrence, as we occasionally meet with cases where women continue to have their periods for some time after conception, and frequently with others where, during lactation, V.] THE SEMINAL FLUID. 97 menstruation goes on with perfect regularity. Any menstrual irregu- larity, however, occurring during the period of a woman's life which we are here considering, and independent of pregnancy, is to be looked upon as an abnormal state, which calls for treatment with a view to the maintenance of her health. These, and other menstrual disorders, constitute a class of diseases to the treatment of which the physician has constantly to address himself. The cause of menstruation is a question which has given rise to a great deal of useless discussion, and to not a few baseless theories. Without broadly asserting that the two phenomena stand to each other in the relation of cause and effect, we are, in the present state of our knowledge, entitled to assume that the periodical discharge depends upon corresponding changes in the ovary, associated with the matura- tion of a Graafian vesicle. This is proved by the examination of the ovaries of women w T ho have died during menstruation, when the ap- pearances already described are generally to be found; by the almost invariable cessation of menstruation when the ovaries have been re- moved; 1 and by the facts which a careful examination of the phenomena of the "rut" of the lower animals discloses. Why the act should recur at periods so regular and constant, is a question which we need scarcely attempt to answer. That, in one animal, a single Graafian vesicle should come to maturity each month, in another, a cluster ripen simultaneously, and, in a third, that evolution should occur at intervals of a year, are facts which display a marvellous accordance with the pur- poses of nature in regard to the propagation of species, but they are facts, too, the ultimate cause of which will continue to baffle the specu- lation of the astutest intellects. Conception, Fecundation, and Impregnation, are terms all of which imply fruitful contact of the male and female elements, so that a new organism comes into existence. The fecundating principle which is contributed by the male is secreted by the testes at the age of puberty, and is known as the semen or seminal fluid. At the time of sexual contact, the excitement of the erectile tissue is such, that, acting through the medium of a ganglionic centre, which is supposed to be situated in the lower portion of the spinal cord, it culminates in an orgasm, during which certain muscular fibres are called into a reflex and convulsive action. The semen is thus ejaculated with considerable force by the fibres of the vasa deferentia, and by the special muscles which sur- round the vesicula? seminales and the prostate gland, its regurgitation towards the bladder being prevented, according to Kobelt, by the tumefaction of the verumontanum which occurs during the period of erection. It is thus thrown for the most part into the upper part of the vagina, and over the os and vaginal portion of the cervix; but it is well known to medical jurists that this, although highly favorable to impregnation, is not essential. On the contrary, there are perhaps few 1 Percival Pott's well-known and often-quoted case, corroborated by similar ob- servations by Cazeaux, Oldham, and others, was long held as conclusive evidence that menstruation in the absence of the ovaries was impossible. A sufficient num- ber of cases have, however, been reported on good authority to show that, excep- tionally, periodic sanguineous discharges may go on in the absence of the ovaries. 7 98 MENSTRUATION AND CONCEPTION. [CHAP. physicians of experience who have not met with cases where women, believing themselves safe, have permitted a certain amount of sexual contact without penetration, and have thus become pregnant. All, in fact, that seems to be essential is contact of the seminal fluid with the pudendum, which is further proved by observations of pregnancy coin- cident with perfect hymen. The semen is a thick, glutinous, whitish fluid, albuminous, heavier than water, and emitting a peculiar odor. If subjected to exami- nation by a considerable magnifying power, it is found to consist of a number of little oval, flattened bodies, which in man are not more than %-qqq of an inch in width, furnished with long filiform tails, which taper gradually to the finest point. A lashing undulating motion is imparted to these bodies, for a certain time after death or ejaculation, varying according to circumstances from several hours to several days. This brisk and constant movement, which has led Kolliker to compare them to ciliated cells, gave rise to the erroneous opinion that they were animalcules, hence the name which they still retain, Spermatozoa. Besides these bodies, there are observed cer- tain minute round and granular masses, varying in number, but always fewer in ripe semen than the Spermatozoa themselves. These are what were originally termed by Wagner, " semi- nal granules," but which have been shown by his subsequent researches, and by those of Kolliker, Leuckart, Spermatozoa and vesicles of evolution. etc., to be Cells within which the Sper- matozoa are developed, and are now termed vesicles of evolution. These again are generally found to be inclosed in groups of from three to seven within parent cells (Fig. 48, b b), but each vesicle of evolution is destined for the development of a single spermatozoon, as is shown in a mature specimen at c. The indi- vidual spermatozoa escape thereafter by rupture of the containing vesi- cle, and may now (a) exhibit their characteristic movements. Some- times, rupture of the vesicles of evolution takes place without absorption of the parent cell, when the appearance produced is that shown at d, where a bundle of spermatozoa is seen, their number corresponding to that of the original vesicles. It is only, it may be observed, by careful examination of the semen in the testes, epididymis, and other portions of the tract, that these several stages may be traced. These elements of the semen are found to float in a limited quantity of clear perfectly homogeneous liquid. Direct experiment on the ova of the Amphibia has proved that it is in the spermatic particles and not in this fluid that the fecundating principle resides. If the spermatozoa are absent, therefore, as in debility, disease, or old age, impregnation is impossible, and it is their absence in the semen of hybrids that renders these ani- mals sterile. The Ovum at the stage at which we left it, was escaping, or about V.] CONTACT OF OVUM WITH SPERMATOZOA. 99 to escape, from a ripe Graafian follicle. It is then composed of the following parts (see Fig. 39, p. 79): a. Of a thick transparent membrane, which completely surrounds it, and exhibits no trace of vascularity — the zona pel lucida of Baer, or vitelline membrane of Coste : b. Of a granular yolk contained in this vesicle : c. Of the germinal vesicle of Purkinje : d. Of the germinal spot of Wagner. The Germinal Vesicle, as the period of dehiscence approaches, moves, as we have seen, towards the periphery of the yolk, both it, and the germinal spot within it, being so placed, as to be as near as possible to the point where rupture is about to occur, as if to seek the fertilizing influence of the male. Since Bischoff actually demonstrated the pres- ence of spermatozoa on the ovaries of bitches and rabbits, in whom congress had been permitted at the proper period, few physiologists question the possibility of impregnation occurring while the ovum is yet in the ovary ; and indeed, if true ovarian pregnancy is possible, — which some doubt, — it is only in this way that impregnation can, in these cases occur. It has been generally assumed, however, that a rupture of the walls of the Graafian vesicle could alone permit of such impregnation ; but if we may so far judge from analogy, what has recently been divulged in reference to the penetration of the walls of bloodvessels by the white corpuscles of the blood, and their consequent transformation into pus-cells, we may at least admit the possibility that particles endowed with such mobility may penetrate the attenuated walls of a Graafian vesicle, even before rupture. The germinal vesicle has been designated by some physiologists the germ-cell, and the vesicle which contains the spermatozoon the sperm- cell, it being assumed that the fertilizing product of the latter made its way through the walls of the ovum, and intermingled with the con- tents of the former. In the osseous fishes, and in some animals lower in the scale, it has been shown that a minute opening (micropyle) exists in the zona pellucida, which has been supposed by Dr. Allen Thomson to facilitate the fecundation of ova possessed of very thick external coverings. No reason other than this exists for the belief, which some have entertained, that a similar aperture in the Mammalia facilitates the introduction of the spermatozoa. There are many reasons for be- lieving frhat the germinal vesicle, or germ-cell, plays an important part in conception, but what precise share it takes in the process is hitherto undetermined. The cessation of the characteristic movements of the spermatozoa marks the termination of the period during which their fertilizing in- fluence may be exercised. The duration of the period will, therefore, obviously depend upon the circumstances under which the semen is placed. Its admixture, at the time of ejaculation, with the prostatic fluid and the secretion of Cowper's glands, and, subsequently, with the vaginal and uterine secretions, are obviously circumstances which tend to preserve the spermatozoa, by furnishing a medium in which they may freely float : an absence of these conditions would necessarily cur- tail their vitality. Although we may assume it as possible that im- 100 MENSTRUATION AND CONCEPTION. [CHAP. pregnation may occur in'the ovary, it by no means follows that it can occur nowhere else. But it is certain that the contact between the male and female elements must almost always take place, if not in the ovary, at some point between it and the upper third of the uterine cavity. Bischoff affirms that, by the time the ovum reaches the lower end of the Fallopian tube, its capacity for impregnation is lost, and experiments which have been made, by tying the Fallopian tubes in the lower animals before copulation, so far corroborate this view, which is now generally entertained. There can at least be little doubt that in the great majority of cases among Mammalia, and most probably in the human subject, it is in the upper half, or third, of the Fallopian tube that the meeting of the ovum with the semen takes place. How, then, do the spermatozoa reach the ovum? It cannot for a moment be doubted that the spermatozoa must make their way upwards, in Man, as in the lower animals, from the vagina, to that point where they meet the ovum. 1 There are various possible agencies by means of which this movement may be effected : 1st. By the action of the spermatozoa themselves, which may undoubtedly determine a motion, although it is difficult to conceive why such motion should be in a definite direction. It is highly improbable, therefore, that this is the sole motive. 2d. By the action of the vibratile cilia. This will account, no doubt, for the movement from the middle of the cervix upwards ; but in cases where impregnation has resulted from contact without penetration, the absence of cilia between the vulva and the cervix must leave the movement along this part of the tract to the operation of some other agency. 3d. Muscular peristaltic contractions may also act by propelling the semen in a definite direction. There are various parts of the course which the semen must traverse to which one or other of these forces may be more applicable, but it is more than likely that muscular peristaltic action is the chief moving power. The absence of the vibratile cilia during a menstrual period may raise a difficulty as to the acceptance of one of the above theories, most likely to suggest itself to those who entertain the strongest views as to the identity of the rut and menstruation. But, in regard to this it must be observed, that the period at which impregnation is most likely to occur is some days after, or shortly before, menstruation ; in the one case, the changes in the epithelium of the uterine mucous membrane not having yet commenced, and, in the other, a sufficient period having elapsed to admit of its reparation. Another channel through which, in exceptional cases, the spermatozoa may work their way up, is one which, on the authority of Mauriceau, De Graaf, and Baudelocque, Cazeaux assumes to result from a bifurcation of the Fallopian tube near its uterine extremity, the new canal passing through the uterine walls, and opening near the internal os. As modern anatomists make no mention of such a canal, we may assume its existence to be doubtful ; and even if we admit it, its only physiological importance would be the possibility of the arrest of the ovum there, and the formation of 1 Some speak of the "ovum" only after impregnation, and term it "ovule" prior to this. VI.] DEVELOPMENT OF THE OVUM. 101 what has been called by the older writers " Graviditas in substantia uteri. " A sketch of the development of the ovum, from the period of im- pregnation onwards, will be reserved for the following chapter. CHAPTEE VI. DEVELOPMENT OF THE OVUM. formation of the embryo-cell — cleavage of the yolk — development of the blastodermic vesicle — " serous " and "mucous" layers — the area germinativa and primitive trace — formation of the embryo ; of the umbilical vesicle and omphalo-mesenteric vessels ; of the amnion; of the allantois and umbilical vessels; of the chorion — the liquor amnii — the vitriform body — the decidua ; what is it? dec1dua vera ; reflexa ; serotina — early connection of ovum with decidua — the umbilical cord : vessels ; gelatin of wharton, etc. — knots on cord — the placenta — in birds: in non-placental mammals : in ruminants: in man: maternal and fcetal surfaces of: maternal circulation in: curling arteries: sinuses: veins — fcetal portion: arteries : tufts or villi : veins — functions of the placenta — struc- ture of villi. The development of the ovum in the Mammalia, and especially in Man, is, as regards its earlier stages, a subject still involved in no little obscurity. The important results which have sprung from the studies in comparative physiology, associated with the names of V. Baer, Rathke, Bischoff, Remak, Kolliker, and many others of scarce inferior merit, enable us, with a certain amount of confidence, to fill up gaps in an account of human development, which the very rare oppor- tunities afforded of examining human ova would probably never have revealed, but which the application of strict analogical reasoning enables us to supply. On these principles, the following sketch is based. No attempt will, however, be made to follow the development of individual organs ; but merely to indicate, in what appears to the writer to be the simplest possible manner, the mode in which the envelopes of the embryo are evolved, and the provision which, in successive stages of growth, is made for its nutrition. The disappearance of the germinal vesicle is one of the earliest changes which has been observed. This is not necessarily associated with impregnation, but is rather a sign of the complete maturation of the ovum. Modern physiologists indeed appear to believe that, as a rule, it has nearly, if not entirely, disappeared at the time of the rup- ture of the Graafian vesicle. The formation, however, in its place, of the new embryo-cell, which, having been demonstrated in many animals, 102 DEVELOPMENT OF THE OVUM, [CHAP. is assumed to take place also in the human species, and the changes which immediately occur in the yolk, are undoubted results of the fecundating process, and of the penetration of the walls of the ovum by the spermatozoa. In the outer half of the Fallopian tube, the ovum is believed to have already undergone some of these changes. There can be little doubt, at least, that, even thus early, the germinal vesicle and its spot can no longer be distinguished, and the external surface of the ovum is still covered with some of the granulations in which, within the Graafian vesicle, it was imbedded. The yolk becomes more com- pact, and, as it were, condensed. In the inner half of the tube, the granulations have disappeared, and their place is occupied, on the ex- ternal surface of the ovum, by a thin albuminous layer, which is anal- ogous to the white of the egg in birds. This albuminous layer, like the subjacent zona pellucida, becomes, in the first instance, thicker, and there now commences that most remarkable series of changes prepara- tory to the formation of the embryo, known as the segmentation, or cleavage of the yolk. The first step in this process consists, as is shown in Fig. 49, of the fission of the mass of the yolk into two equal portions, by a deep Fig. 49. Fig. 50. Fig. 51. Successive stages of the cleavage of the yolk. furrow on either side, which ultimately, by uniting in the centre, com- pletes the division. These again, by a repetition of the process, become subdivided, so that four spheres are now observed to occupy the cavity of the zona pellucida. Each of these divisions of the yolk proceeds, pari passu, with a corresponding duplication of the " embryo cell," already referred to. After precisely the same fashion, the spherules become still further subdivided into 8, 16, 32, 64, and so on, until, on the arrival of the ovum at the uterine extremity of the Fallopian tube, the yolk presents the appearance shown in Fig. 51, which has been well compared to a mulberry. It is from this germ-mass that the whole organization of the embryo is gradually evolved. In Mammalia, the process of segmentation affects the whole mass of the yolk, which is protoplasmic. But there are great differences in this respect in other animals. In Birds and Reptiles, the cicatncula, or white spot, lying on the side of the yolk which floats uppermost, alone undergoes this process. A distinction is, therefore, to be made between the ova of these animals in which the yolk is entirely segmented, and is therefore germinal, and those in which a part only is directly germinal and another is nutritive. Having arrived in the uterine cavity, the ovum, on examination, VI.] THE BLASTODERMIC VESICLE. 103 Fig. 52. ^^. appears as if the whole of the granular germ-mass had been absorbed. And to some extent, no doubt, a process of solution or absorption has taken place, the centre of the cavity being again occupied by a fluid which is limpid and transparent. A more careful examination shows, however, that a large proportion of the granules become condensed towards the inner surface of the zona pellucida, assuming the form of true cells, of a hexagonal or pentagonal appearance from the pressure which they exercise upon each other. While these changes are going on, a rotatory movement of the yolk takes place, during which, possibly by centrifugal attraction, the cells retreat from the centre towards the circumference, and ultimately form a new membrane. This spheroidal vesicle within the zona pellucida, is the structure out of which, step by step, the entire embryonic struc- tures are evolved. It is the blasto- dermic vesicle of Bischoff and Coste. From the shape of the cells of which it is originally composed, the ovum now presents the appearance shown in Fig. 52, which indicates also a considerable increase in size, owing to the rapid augmentation of its fluid contents by absorption from the uterus, and the simultaneous de- velopment of the blastodermic vesi- cle, which now exhibits great and independent vital energy. At one point of its surface, a certain num- ber of the original segmentary masses and cells form, by their aggre- gation, the appearance which is represented in the same figure. This, which is at first round, and subsequently becomes oval, is recognized by its whitish opaque appearance. It is called the area germinativa, and constantly increases in size by the development of fresh cells, and by and by splits into two layers, a division which rapidly extends throughout the whole blastodermic vesicle. The external of these two layers was originally called the " serous," the internal the "mucous" layer. As our object is to enter upon this subject only in so far as is essential to a knowledge of the points in development which are of special obstetric interest, we shall here refer to these two layers only. There is another layer, however, intermediate between the two, which further subdivides as evolution advances, a knowledge of which is essential to a thorough description of the various organs. This was first called the "vascular" layer, but there are many points in reference to it which are still under consideration, and in a measure involved in obscurity. This seems to be an additional reason why, even at the risk of a charge of inaccuracy here and there, we should not enter upon the difficult subject of the intermediate layer. The area germinativa, at first homogeneous in appearance, soon shows in its centre a clear space, called the area pellucida, bounded by a denser layer of cells, which are manifestly more opaque. The first External surface of the ovum, showing the area germinativa. c 104 DEVELOPMENT OF THE OVUM. [CHAP. appearance of definite embryonic structure is a shallow groove lying lengthwise in the area pellucida. This is the primitive trace, the earliest indication of the cerebro- spinal canal. If viewed in section, this groove (Fig. 53 a) is seen to lie between two lateral eminences called the lamince dorsales (c c), Diagram showing the earliest format^ of the embryo. which We here demonstrate, as it illustrates a law in de- velopment, of which, in the evolution of special organs, we find many illustrations. This diagram, after Remak, is the only one in the series in which the middle layer is indicated, showing at o the first trace of the vertebral column, and at p p the subdivision of this layer, indicat- ing the origin of the pleuro-peritoneal cavity. The lowest in the figure is the mucous layer. In the development of the tube of which the groove is the trace, the lamina? dorsales rise, and, folding together, meet in the middle line, and there unite. Consequently the cutaneous or corneal layer (Hornblatt of Kolliker) secretes from a portion of its sur- face elements which, within the tube, ultimately become the cerebro- spinal nervous centre. Among other instances of this method of de- velopment by involution, the formation of the lens and vitreous body, in the construction of the eye, is a striking example, both the cuticle and these structures being originally portions of the same external or corneal surface. The albuminous layer having now disappeared, and the zona pellncida having in great part lost its thickness, the formation of the embryo be- comes more distinctly manifested by a rolling or folding inwards both of the sides and of the extremities of the area germinativa. At this stage, the embryo has the appearance of a curved gutter, with a larger (cephalic) and a smaller (caudal) extremity. A glance at the diagram (Fig. 54) will show that its external or epidermic surface is continuous with the external or serous layer (s) of the blastodermic vesicle. About this period, the blastodermic vesicle becomes divided into two parts, as is indicated by the horizontal dotted line in this and the following diagram, the lower portion being embryonic, and the large cavity above forming the umbilical vesicle (u). The embryonic portion constantly increases, while the umbilical vesicle progressively diminishes, as if the development of the former took place at the expense of the latter: this is made clear in the series of diagrams. The two small projections (a a) show the earliest stage of the formation, by a process of involution, of the amnion, an important structure, the further development of which will be traced presently. The blastodermic vesicle, then, is surrounded by the zona pellucida z. It is itself composed of two layers, the ex- ternal or serous (s), which is continuous with the external surface of the embryo, and from which the amnion is developed ; and the internal or mucous (m), which subsequently subdivides as we have seen. If we look, however, at the mucous layer, in its original and simplest form, we may assume that the umbilical vesicle and the intestinal surface of VI.] THE AMNION AND CHORION. 105 the embryo are identical and continuous, both being derived from the same layer. In Fig. 55, the same parts are shown in a more advanced stage of development. The embryonic portion of the blastodermic vesicle is more defined, and of larger size, and the umbilical vesicle is diminished in a corresponding degree, while the communication between the two Fig. 54. Fig. 55. Diagram showing early stage of development. Further development of the ovum. is rendered more distinct. The first indications are now shown on the latter of a vascular system. This is the omphalo-mesenteric system, or circulation of the yolk, from which is formed ultimately the portal circulation of the foetus. The umbilical vessels spring, as we shall see, from another source. The amnionic folds (a a) are now seen to project more over the embryo. The next step in the process of development is shown in Fig. 56, in which the whole ovum shows an increase in size. The amnionic folds project so far that they are nearly in contact, the embryo being thus inclosed in a sac, which has as yet an opening at a a. About this period, a very important structure, the allantois, makes its first ap- pearance under the form of a small pear-shaped vesicle (p), which springs from the mucous layer, near the caudal extremity of the embryo. This little organ has, as we shall find, a most important part to play in providing an apparatus, and channel of communication, whereby the circulation and respiration of the foetus may be efficiently maintained. This vesicle, in Birds, reaches a very considerable size, so much so as completely to surround the yolk sac, so that, through the shell and its membrane, it comes into actual relation with the external air. In those mammals, in whom the placenta (an organ to be here- after described) surrounds the ovum, the allantois has in like manner a considerable development; but, in the human race, where its function, though not less important, may be said to be comparatively of a tem- porary nature, it never reaches any considerable size. It is originally hollow, and is the receptacle for the secretion of the Wolffian bodies, and subsequently for that of the true kidneys when formed. It is not, however, correct to suppose that it gives origin to the urinary bladder, but its pedicle, the urachus, forms the suspensory ligament of the bladder, and may be traced in adult life. At a very early period of 106 DEVELOPMENT OF THE OVUM. [CHAP. its formation, vessels make their appearance upon it, and shortly after this (probably in a few days) it becomes elongated and, as it were, 'pro- jects these vessels, which are the umbilical arteries and veins, towards the surface of the ovum, with which it comes into contact at that part where the placenta is about to form. It is not, indeed, until this has taken place that the outer of the two foetal envelopes may probably be said to be completed. The foetal covering here alluded to is the chorion, which may thus be considered as composed of the external or serous layer, with the remains — should these still exist — of the zona pellucida on its external, and some portions of the allantois on its internal surface. The Chorion thus constituted, becomes abundantly supplied with vessels from the allantois, which soon pervade it in its whole extent, as is shown in the accompanying diagram (Fig. 57). Prior to this, small projections have Fig. 57. Fig 56 Development in a more advanced stage. Completion of the amnion, and formation of the umbilical cord. appeared on the external surface of the chorion, which are the rudi- ments of the long shaggy villi with which the ovum is seen to be covered in abortions occurring in the early weeks of pregnancy. The allantois having now fulfilled its function, dwindles to a mere cord, within which a minute vesicle may be detected by careful examination, as representing the original cavity. It is probable that the allantois forms about the tenth clay after impregnation, and runs its course in a few days more ; so that it is not to be wondered at, that some physiol- ogists have doubted its existence in the human race, seeing that its limits have not been clearly demonstrated. Analogy, however, enables us confidently to assume that, without it, there could be no vascularity of the chorion, a condition which would involve a speedy arrest of development. At first, it carries two arteries and two veins ; but the vein of the right side becomes obliterated about the fifth or sixth week, so that there are found from this period till the time of birth, two umbilical arteries and one umbilical vein. VI.] THE AMNION AND CHORION. 107 After the formation of the allantois, the umbilical vesicle rapidly shrinks, and is often seen, in abortions at the sixth week, under the form of a vesicle no larger than a pea, connected with the small intes- tines of the embryo by means of a long and narrow 7 pedicle ; and its flattened yellowish vestige may with care be detected much later, lying not far from the place of implantation of the umbilical cord into the placenta, between the chorion and amnion. (See Fig. 71.) The om- phalo-mesenteric vessels atrophy, along with the organ to which they belong; and the communication which existed between the vesicle and the alimentary canal, becomes more and more curtailed, and ultimately obliterated. There can be no doubt, however, that in the earliest stages of the development of the ovum, and up to the period of the formation of the allantois, the embryo derives its chief nourishment from the whitish-yellow fluid, which is contained in the umbilical vesicle, and which has been found to contain numerous fatty cells and globules. But, with the formation of the allantois and the vascularity of the chorion, the necessity for nutrition from this source ceases, and the umbilical vesicle, which at one time formed the greater part of the bulk of the ovum, now withers, and ultimately disappears. At the same time that this dwindling of the umbilical vesicle takes place, the development of the amnion goes on with considerable rapidity. In Fig. 57 the completed process of involution, which results in the formation of the cavity of the amnion, is shown, as are the earlier stages in the preceding diagrams. The amnion thus forms a close cavity or sac, which consists of two layers, and is contractile; and in which, hence- forth, the foetus floats freely, protected by the fluid which it contains, from shock and external influences. By the absorption of the original amnionic folds, at the point where they come into contact (see the dot- ted line below a), the amnion becomes completely detached from that portion of the serous layer of the blastodermic vesicle, which we have shown to enter into the formation of the chorion. The amnion thus forms a sheath for the umbilical cord, and from the margins of the ventral aperture or umbilicus, is continuous, as it has been from the first, with the surface of the embryo. When completed, it constitutes the internal membrane of the ovum; and from its inner surface there exudes, a liquid (liquor amnii) which is essential to the safety and fur- ther development of the embryo, — not by affording it nourishment, to any extent, but by the mechanical support and protection which it con- stantly maintains. The liquid consists of water, holding in solution a small quantity of albumen and salts. It is at first limpid, but, towards the end of pregnancy, it becomes of a higher specific gravity, and is often milky, or of a darker color, with numerous albuminous flakes. When the hue is greenish, or dark in shade, this is probably due to the escape of the contents of the bowel. The quantity of the liquid varies extremely, and that, too, without apparent cause ; and while its actual quantity may be said to augment during the whole period of gestation, it is generally admitted that, relatively to the size of the foetus, it increases during the first half of pregnancy, and diminishes from that time onwards. In addition to the protection of the foetus 108 DEVELOPMENT OF THE OVUM. [CHAP. from shock, which must manifestly be exercised to the greatest advan- tage during the early months, the liquor amnii gives room for the movements of the foetus, which we cannot doubt to be essential to its proper development, and for changes in position or posture, in obedi- ence to the laws of gravity. It protects, also, the umbilical cord from pressure; and, during labor, prevents the walls of the contracting uterus from pressing prematurely on the surface of the child, while it safely and expeditiously effects the mechanical dilatation of the os. Finally, omitting, for the present, the possibility of its being a source of nutriment, it is of great assistance to the accoucheur, — preventing the firm contraction of the uterus upon the child, and so facilitating, in many ways, both manual and instrumental operations. External to the amnion, the interval between it and the chorion is occupied by a soft and gelatinous substance, to which Velpeau gave the name of vitriform body ; and imbedded in which is found the re- mains of the umbilical vesicle. The long pedicle of the umbilical vesi- cle penetrates the cord, by an aperture in its sheath. The closure of the amnionic cavity, the formation of the allantois, and the connection thus ultimately established between the embryo and the exterior of the ovum, complete the essential parts of the ovum. The latter now consists — a. Of the Embryo. b. Of the Liquor Amnii, in which it is suspended. c. Of the membrane of the Amnion, which is the internal membrane of the ovum, is continuous with the external surface of the embryo, and forms a sheath to the umbilical cord. The pedicle of the umbili- cal vesicle passes through an aperture in this sheath. d. Of the Urachus or pedicle of the Allantois, and other parts which, together, form the Umbilical Cord. e. Of a space between the amnion and the chorion, containing the remains of the vitriform fluid and of the Umbilical Vesicle. /. Of the Chorion, — the external envelope of the ovum. These parts, although deriving, no doubt, the supply of material necessary for their growth from the parent, are strictly of embryonic origin, or spring from parts which take their rise in connection with the embryo or the peripheral membranes of the ovum. Other struc- tures, however, are simultaneously developed, which may be regarded as in whole or in part maternal. The outermost of the three coverings of the ovum, one which, ac- cording to every hypothesis hitherto advanced, must be looked upon as purely maternal in its origin, is the decidua. The theory originally propounded by Hunter, and adopted by the great bulk of physiologists of the early part of the present century was simply this : The conges- tion and excitement coincident with impregnation, caused, on the inner surface of the uterus an exudation of a new formation of the nature of coagulable lymph, which closed the orifices of the Fallopian tubes, leaving only one opening, corresponding to the internal os. The ovum, on its arrival in the uterine cavity, was assumed to push this mem- VI.] FORMATION OF THE DECIDUA, 109 Diagram, showing Hunter's theory as to the formation of decidua. brane before it, so that the decidua became naturally divided into two parts, that which adhered to the uterine surface [decidua vera, a), and that which invested the ovum (decidua reflexa, b). Subsequent ob- servation having shown that a portion of membrane, identical in its structure with these, was found behind the ovum, — between it and the uterine wall, — this was regarded as a formation subsequent to the arrival of the ovum, and was named the decidua serotina. This theory owed its general acceptance to the fact, that it afforded an explanation of what had frequently been observed in abor- tions — that the complete ovum was found to be inclosed in a pouch, which was shed from the uterus, and which thus derived its name. The view universally adopted by modern physiologists is, however, quite different from this. We have already seen in our notice of the mucous membrane of the uterus, as observed in women who have died during menstruation, that it is at these periods greatly hypertrophied and congested, and, in con- sequence, thrown into convolutions. (See Fig. 47.) Up to a certain point the changes after impregnation are identical with those which accompany the menstrual molimen. According to Robin, the colum- nar and ciliated epithelium is partly exchanged, during the progress of pregnancy, for the tessellated variety, and partly desquamated. Sharpey and Weber found that the decidua vera was, allowing for the changes above mentioned, identical in structure with the mucous mem- brane of the uterus ; and, especially, that the characteristic tubular glands were abundant, and much more distinct than in the unimpreg- nated condition. By others, the orifices of the Fallopian tubes were found to be free. As regards the decidua reflexa, greater difficulties had to be surmounted. If this portion of the membrane be examined at an advanced period of pregnancy, it is found to be thin and trans- parent, if indeed it can be separated from the decidua vera; and it then presents no trace whatever of the tubular glands. At an earlier period, the glands are found to be absent in the central or more promi- nent portion only, becoming more distinct, however, as we approach its point of contact with the decidua vera. In fact, we may assume, with Coste, that the views of Bischoff are, on this subject, incorrect, and that, on its first formation, the decidua reflexa is identical in its structure with the decidua vera. All this points irresistibly to the conclusion that the decidua is nothing else than the uterine mucous membrane, altered to suit the requirements of the case. The main difficulty which, on this view, will suggest itself to the student of physiology, is to account for the manner in which the ovum gets behind the mucous membrane. Here we must be content with theory; but it is a theory founded directly on the facts which modern physiology has revealed, and certainly preferable to that of Hunter, more especially as accounting for the existence of the decidua serotina. 110 DEVELOPMENT OF THE OVUM [CHAP. Fig. 59. I IHi Formation of clecidua; first stage. The ovum, on its arrival in the uterine cavity, is for a certain time free from all adhesion. Probably, it becomes arrested in one of the sulci between the convolutions into which the mucous membrane is thrown, and there it contracts ad- hesions, at the point where the placenta will presently be formed. On either side of it, there now rise projections of the mucous mem- brane (Fig. 59), as we have seen to occur in the formation of the amnion, and in that of the organs of special sense: the folds meet in the centre, and the evolution is com- plete, a (Fig. 60) being the decidua reflexa, b the decidua vera, and c the decidua serotina. The villi, which at this time are abundantly de- veloped on the surface of the ovum, are assumed by some to be received into the ori- fices of the uterine glands, and, indeed, Sharpey actu- ally found this to take place in the case of the bitch. The simple fact of extra-uterine pregnancy seems, however, sufficient to show that, al- though this may occur, it is by no means essential as a step in development. But, whatever view we may be inclined to take of the theory, the facts are these: if we open the uterus of a woman, about the fifth week of preg- nancy, we find, almost certainly, a tumor in the neighborhood of the fundus, and projecting into the cavity of the uterus. The Fallopian tubes are open, and the membrane which covers the tumor is continu- ous, and identical in structure, with that which lines the uterine cavity, the glands being probably more distinct near its base. The tumor, on being incised, discloses a cavity containing an ovum. All this seems to indicate that the modern theory is, at least, more likely to be correct than any hitherto advanced. If, in the course of such an examination as has just been indicated, the cavity be carefully opened, and a flap turned down, the ovum, quite uninjured, may then be observed, sometimes bathed in blood when bloodvessels have been injured. Its external surface will be seen bristling with villi, and on the inner surface of the everted flap, small depressions or lacunae may be noticed, into which the villi dip, and by means of which, no doubt, material is obtained for the time from the circulation of the mother. If, again, we cautiously remove the ovum and wash out the cavity, we shall find that the lacunse on the side of the decidua serotina are much deeper and more numerous. This marks the place at which the placenta is about to form. If we look again at Fig. 61, we may observe that in the most pro- Formation of decidua completed. VI.] THE UMBILICAL CORD. Ill Fig. 61. jecting part of the ovum, which is the centre of the everted flap, the membrane has become thin and exsanguine; and here, even at this early period, we would probably look in vain for the tubular glands. This is the commencement of another and an important change which goes on, pari passu, with the develop- ment of the placenta. Those villi of the chorion which pass towards the cle- cidua serotina are more and more de- veloped, and become imbedded in the latter, the two together forming the placenta, an organ to be immediately described. So soon as this new con- nection is thoroughly established, the villi over the remaining surface of tl ic Flap of decidua reflexa turned down, dis- closing the ovum. ovum diminish or cease to grow in the same proportion; and, as the ovum ex- tends, they become thin and scattered over that side of the chorion which is most distant from the placenta, and are ultimately absorbed, the external sur- face of the chorion being then perfectly smooth. With this, the decidua reflexa loses its vascularity, the vessels becoming obliterated from the centre of the projecting part towards the circumference. As development progresses, the ovum steadily increases in size, and the cavity which exists between the two layers of decidua becomes, in consequence of this, encroached upon, until, about the third month, the two come into con- tact, and the whole of the uterine cavity is then occupied by the foetus and its membranes. It is impossible after this stage to distinguish or separate the decidua vera from the decidua reflexa, which has led Dr. A. Farre to think it probable that the decidua reflexa, after becoming extremely attenuated, ultimately disappears entirely. We do not doubt, however, that although it may become very thin, it may with care be traced. Let us now turn again to the interior of the ovum, the essential parts of which were completed by the formation of the allantois. The elongation of the pedicle of the allantois, and the obliteration of its cavity takes place with great rapidity, and, at the same time, the cord becomes greatly increased in length. From this period onwards, the Umbilical Cord consists of the following parts : the amnionic sheath, which entirely surrounds it, save at one point, where a small slit gives egress to the pedicle of the shrunken umbilical vesicle ; the two umbilical arteries and the umbilical vein, which form the greater portion of the bulk of the cord ; that portion of the pedicle of the umbilical vesicle, which extends from the umbilicus to the point of exit; and lastly, the remains of the pedicle of the allantois. By means of the villi of the chorion, acting, as Professor Owen has observed, like the spongioles of a plant, nutriment is extracted from the maternal soil in which it is imbedded, each vascular tuft being, as it were, an independent centre of respiration and nutrition. But, with the complete establishment of the umbilical communication — for it cannot as yet be termed a "cord" — these functions become localized in the human race, and there now 112 DEVELOPMENT OF THE OVUM. [CHAP. begins to form, at the point, probably, where the allantois first touched the wall of the ovum, an important special organ of connection, the Placenta, in which externally the umbilical cord terminates. The Umbilical Cord, being composed of the elements above detailed, con- ducts the foetal blood from the bifurcation of the abdominal aorta to the placenta by its two arteries, and brings back the same blood by means of its single vein, it having meanwhile undergone certain changes. The obliteration of the umbilical vesicle soon admits of the closure of the aperture alluded to, and thus reduces the contents of the cord to the vessels above mentioned, and the loop of bowel which still protrudes by the umbilical orifice. This communication between child and pla- centa varies considerably in length. At first, it is short, and is also thick in proportion to the size of the ventral aperture, but soon becomes considerably elongated. Even at. the termination of pregnancy, how- ever, great varieties are observed, it being in some instances no more than a few inches in length, and in others extending to five feet or even more. Its average length, at the full time, may be assumed to be somewhere about twenty inches. The vessels, which are devoid of valves, and which give off no branches in the cord, are disposed in regard to each other, in a manner somewhat peculiar. Firmly bound together by a tenacious substance called the gelatin of Wharton, the quantity of which determines in a great measure the thickness of the cord, the vessels are invariably twisted like the handle of a basket. This does not take place in an irregular manner; on the contrary the twist is, nine times out of ten, from right to left, and, invariably, the vein forms as it were a centre or axis, around which the arteries are arranged in an irregularly spiral form. This twisting, which has been observed as early as the second month, is supposed to depend partly upon the movements of the foetus, and partly upon a more rapid growth of the arteries than of the other tissues of the cord. On an average, the cord is about the thickness of the little finger. Many anomalies have been observed in its formation. One artery; three arteries; and even three veins have been met with, without anything untoward hav- ing occurred, in any stage of the case, in the course of pregnancy. When the cord is too long, knots have frequently been observed upon it. These are, doubtless, due to the movements of the foetus, and are much more likely to occur if, along with great length of the cord, there is an excess of the liquor amnii. It is easy to understand how, under such circumstances, the foetus might float through a large loop, and a knot be the immediate or ultimate result. It is conceivable that danger might arise from this, in the course of labor, should any me- chanical complication tend to draw the knot tighter; but all experience seems to show, that these knots are not to be looked upon as dangers, unless under such very exceptional circumstances. The cord is of very considerable strength, as a general rule, as is shown in cases where: — often in error — considerable force is brought to bear upon it, in attempts to remove the placenta when this organ is retained. At other times, a very moderate tension will suffice to break it. It is firmly adherent, at its foetal extremity, to the abdominal walls of the child, and, at the placenta, it is found to be intimately con- VI.] THE PLACENTA. 113 nectecl with the tissues of the chorion. Externally, its connection with the amnionic sheath is of slighter character, and this is more particu- larly to be observed near the placenta, where the amnion often passes off from it near to the point of its insertion, and thus forms a sort of infundibuliform investment, which has been noticed by many authors. Nerves and lymphatics have been described as appertaining to the umbilical cord ; but these, if present, are so difficult to trace that their existence is very generally doubted. The Placenta. — The ovum is, as we have seen, supplied with nutri- ment, in the first instance, directly from the contents of the umbilical vesicle, through the channel of communication which exists between it and the intestinal canal ; subsequently, in all probability, through the medium of the omphalo-mesenteric circulation ; and, at a still later period, before the formation of the allantois, through the villi of the chorion, by imbibition. When, through the agency of the allantois, the umbilical vessels have been projected to the walls of the ovum, a more direct means of communication is at once established. In the lowest Mammalia, which are hence called ^non -placental," no further change takes place in this respect — the whole periphery of the chorion exchanging elements with the maternal parts, as in the early human ovum — until the period of birth. In many of the higher Mammalia, as in the Ruminants, certain portions of the surface of the ovum con- tract with the superimposed maternal parts more intimate adhesions, while other parts become comparatively deprived of their villi. An increase of tissue at these points gives rise to the formation of " cotyle- dons," which may be looked upon as so many miniature placentae, the structure of the uterus, forming the cotyledons, being in these animals permanent. Many other and interesting varieties arc observed, among which we may mention the diffused placenta of the mare and pig, and the zonal placenta of the Carnivora. In man, however, and the higher orders, the mass is confluent and concentrated at one spot, and thus forms the single connective organ which is known as the Placenta. The disappearance of the villi over the remaining portion of the sur- face of the chorion, concentrates within the new organ the functions of nutrition and respiration, which it has thenceforth to discharge. A study of its structure is of peculiar interest to the obstetrician, as any diseased or other condition which may affect the due performance of its functions, must necessarily exercise an important influence on the healthy and normal development of the embryo. In many of the animals in whom a placenta exists, that portion which is derived from the ovum may be readily separated from the part which is of maternal origin ; but, in the human placenta, no such separation is in any way possible, so intimately are the two elements incorporated together. We must, nevertheless, look upon the placenta as composed originally of two distinct parts or layers, which are accordingly named the matwnal and foetal portions of the placenta. The maternal portion is developed out of that part of the uterine mucous membrane to which the ovum attached itself on its arrival in the uterus. In other words, it is the decidua serotina. No sooner has its formation commenced, than the bloodvessels in the corresponding 8 114 DEVELOPMENT OF THE OVUM. [CHAP. region of the uterus become notably enlarged, the arteries retaining their characteristic spiral form, while the diameter of the venous trunks becomes so much increased, that they are now called sinuses. In the earlier stages of formation, the maternal and foetal vessels are easily seen to run in distinct structures, which may be separated artificially from one another, without rupture of any of the vessels. But, as the placenta becomes more consolidated, the interweaving of the two sets of structures becomes more intimate, by the thinning out of the interven- ing material, while the villous ramification of the foetal part, becoming more and more extended, is accompanied by a corresponding inflection of the maternal structure and vessels over every part of the villous surface; so that, at last, there is produced so complete a combination or interlacing of the two as to make it quite impossible to separate them, or even to distinguish accurately the confines between the struc- ture which was originally foetal and villous, and that which was ma- ternal, or decidual and venous. Numerous observations have proved this, but none more distinctly than the experiments of Bonami, to which we shall immediately refer. Before doing so, however, it is necessary to observe that, on separating a placenta from its uterine attachment by cautiously drawing the parts asunder, it becomes obvious that a special tissue intervenes. This has been described as separating into two thin gelatinous layers, consisting when in situ of interlacing lamellae, adhering at certain points only of their surface, and thus forming cells which may be shown on gently drawing the parts asunder. This is the interplaeental or inter liter o -placental tissue. Bonami demonstrated so far the structure of the placenta by colored injections as follows: He injected — 1st. Red, from the iliac and ovarian veins : 2d. Blue, from the uterine arteries : 3d. White, from the umbilical vein : 4th. Yellow, from one umbilical artery, the other being tied to pre- vent the regurgitation from the anastomosis, which would otherwise have occurred. Careful observation and dissection then disclosed the following facts : that numerous red vessels were visible through the amnion on the foetal surface of the placenta; that red and blue vessels, the former straight and the latter spiral, were seen to pass in great numbers through the utero-placen tal tissue, and to penetrate the placenta; and, finally, that a white and yellow network was distinctly seen on the uterine surface of the placenta. As no escape of the injected fluids had taken place into the intermediate tissues, the facts speak for themselves. Before proceeding to consider the more minute structure of the pla- centa, some general description of the physical characters of the mature organ may here be given. On its removal from the body, it is found to be a soft spongy mass, about twenty ounces in weight, and seven and a half inches in its greatest width. These are, of course, average di- mensions, as it varies greatly in size; and, on the same principle, it is described as being three-fourths of an inch thick in the centre, and one- eighth to one-fourth of an inch at the margin. It is usually somewhat oval in form, and the umbilical cord is inserted in the centre of its VI.] STRUCTURE OF THE PLACENTA. 115 foetal surface. It may be situated at any portion of the uterine surface, even over the os, but its usual site is the neighborhood of the fundus. It presents for observation an internal or foetal, and an external or uterine surface. The internal surface (Fig. 62) is smooth, and is covered by the am- nion, through which the vessels are distinctly seen to divide and sub- Fig. 62. Foetal surface of the placenta. divide before plunging into the tissue beneath. The external or uterine surface (Fig. 63) is very different from the former. It is slightly rough on the surface, giving a peculiar granular impression to the finger, very familiar to every obstetrician. It is, moreover, divided into irregular lobes, which may be easily torn or separated from each other. Indeed, examined from this side, the substance of the pla- centa may be said to be brittle. This surface is covered, as has been shown, by a thin layer of utero-placental tissue, through which, with some care, and by floating the placenta in water, the oblique passage of the veins from the uterus may be detected. The margin is continuous throughout with the membranes; the foetal portion with the chorion, and the maternal with the decidua. Peculiarities in the structure of the placenta, and in the manner of its connection with the umbilical cord, are not very uncommon. What is known as battledore placenta is one of the most common of these, the cord being then attached, not to the centre, but to the margin of the placenta, giving it something of the form from which it has derived its name. In other cases, although much more rarely, small lobes or cotyledons are found detached from the general mass, as in a case fig- 116 DEVELOPMENT OF THE OVUM [CHAP. ured by Dubois; while in twin cases certain modifications are observed which are essential to the dual development, but which will fall more naturally to be considered under the section relating to plural preg- nancy. The structure of the placenta being thus complicated, it is not to be wondered at that great difficulties have been encountered in determin- ing what is the nature of the communication which there takes place between the foetal and maternal circulating systems. An opinion long obtained that there was a direct commingling of the two currents, and that blood passed from the uterine arteries directly to the foetus, and, Fig. 63. Maternal surface of the placenta. after there yielding a portion of its vital constituents, returned again by the uterine veins. The earliest attempts at injection being no doubt unskilfully executed, seem to have encouraged this belief. Modern physiologists have long since dispelled this illusion, and the experiments of Bonami above cited demonstrate, along with others, that there is a maternal and a foetal circulation, each being distinct from the other as regards continuity of current down to its uttermost conduits. The vessels of the two systems are, however, in intimate contact throughout, as is made obvious at once by anatomical demonstration, and by a knowledge