■ m m ■KmSkct 9bE MB warn wM si ■B H s&si LIBRARY OF CONGRESS, TU Shelf JaJItf UNITED STATES OF AMERICA. DISEASES OF THE DIGESTIVE ORGANS » IN INFANCY AND CHILDHOOD. STARR. DISEASES OF THE DIGESTIVE ORGANS IN INFANCY AND CHILDHOOD, CHAPTERS ON THE INVESTIGATION OF DISEASE, AND ON THE GENERAL MANAGEMENT OF CHILDREN. BY V LOUIS STARR, M.D., CLINICAL PROFESSOR OF DISEASES OF CHILDREN IN THE HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA; PHYSICIAN TO THE CHILDREN'S HOSPITAL, PHILADELPHIA, ETC., ETC. WITH COLORED PLATE AND OTHER ILLUSTRATIONS. ? 3 $~J PHILADELPHIA : P. BLAKISTON, SON & CO., No. 1012 Walnut Street. 1886. -.< CO Copyright, 1886, by Louis Starr, m.d. TO PROFESSOR JOHN ASHHURST, Jr., M.D. THIS VOLUME IS DEDICATED, AS A Tribute to his Genius as a Surgeon and Author, and IN Grateful Remembrance of Many Acts of Kindness. Y.KI PREFACE. It is the author's object, in this book, to give prominence to a class of disorders constituting a large proportion of the ailments of childhood, but often too briefly considered in works on paediatrics. For the successful treatment of 'the diseases of the digestive organs in infancy and child- hood, attention to the general regimen is quite as im- portant as the administration of drugs, and it is upon the former that the student and younger practitioner are usually the least thoroughly instructed. So much may be done by the selection of suitable food, by artificial digestion, by regulating the clothing, bathing and other elements of hygiene, that the author, without neglecting therapeutics, has given greater promi- nence to these points. The chapter on the investigation of disease does not necessarily belong to a work on disorders of the digestive organs, but as so much difficulty is experienced by stu- dents in the study of disease in children, it has been xiu XIV PREFACE. incorporated as an aid to such. In the article on the general management of children, the effort has been made to present to the inexperienced results that can only be obtained by much study and practical work. The author is indebted to Dr. Henry D. Harvey for his aid in preparing the index, and to the pencil of Dr. John Madison Taylor for the illustrations. LOUIS STARR. 1922 Spruce St., Philadelphia. April, 1886. CONTENTS. PART I.-INTR0DUCTI0N. PAGE THE INVESTIGATION OF DISEASE, .... 17 1. Questioning the Attendants, . . . . . .18 2. Inspecting the Child, 21 3. Physical Examination, 35 PART II— DISEASES OF THE DIGESTIVE ORGANS. CHAPTER I.— AFFECTIONS OF THE MOUTH AND THROAT, 59 1. Catarrhal Stomatitis, . 59 2. Aphthous Stomatitis, 62 3. Ulcerative Stomatitis, . 67 4. Gangrenous Stomatitis — Noma, ..... 72 5. Parasitic Stomatitis — Thrush, 79 6. Dentition, 86 7. Simple Pharyngitis, ........ 103 8. Superficial Catarrh of the Tonsils, 107 9. Follicular Tonsillitis, .108 10. Suppurative Tonsillitis, 112 11. Hypertrophy of the Tonsils, 116 12. Retropharyngeal Abscess, 119 CHAPTER II.— AFFECTIONS OF THE STOMACH AND INTESTINES, . ... 1. Acute Gastric Catarrh, . 2. Chronic Gastric Catarrh, 3. Chronic Gastro-Intestinal Catarrh 4. Acute Intestinal Catarrh, 5. Chronic Intestinal Catarrh — Chronic Entero-Coliti XV 122 122 126 136 152 161 XVI CONTENTS. PAGE 6. Entero-Colitis, 175 7. Cholera Infantum, 188 8. Inflammation of the Colon and Rectum — Dysentery, . 194 9. Tubercular Ulceration of the Intestines, . . . 198 10. Colic, 201 11. Habitual Constipation, 205 12. Simple Atrophy, 211 13. Typhlitis and Perityphlitis, 220 14. Intussusception, 230 15. Intestinal Worms, 248 CHAPTER III.— CASEOUS DEGENERATION AND TU- BERCULOSIS OF THE MESENTERIC GLANDS —TABES MESENTERICA, 266 CHAPTER IV.— AFFECTIONS OF THE LIVER, . . 275 1. Jaundice, 275 2. Congestion of the Liver, 281 3. Fatty Liver, 285 4. Amyloid Liver 287 5. Syphilitic Inflammation of the Liver, .... 291 6. Cirrhosis of the Liver, 292 7. Suppurative Hepatitis, 298 CHAPTER V.— AFFECTIONS OF THE PERITONEUM, . 306 1. Peritonitis, 306 2. Tubercular Peritonitis, 314 3. Ascites, 322 PART III— THE GENERAL MANAGEMENT OF CHILDREN. 1. Feeding, 329 2. Bathing, 365 3. Clothing, 368 4- Sleep, 370 5. Exercise, 372 INDEX, 375 DISEASES OF THE DIGESTIVE ORGANS IN INFANCY AND CHILDHOOD. PART I.— INTRODUCTION. THE INVESTIGATION OF DISEASE. The clinical investigation of disease in children, usually considered so difficult, is in some respects, easier than the same study in adults. It is easier because in the child disease is commonly un- complicated, rarely has its course and symptoms modified by tissue lesions the result of previous affections, and never by vicious habits, such as the abuse of stimulants and nar- cotics, or by mental over-work and nerve-strain. The con- fusing element of mis-stated subjective symptoms is also absent, while correct diagnosis is greatly aided by the facility with which physical examination of the whole body may be practiced. That there are difficulties to be encountered, and very grave ones too, is equally certain. The absence of speech in the infant deprives us of the important assistance afforded by correctly described subjective symptoms, and renders it necessary to look to the mother or nurse for the history of an 2 i 7 1 8 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. illness. In older children the case is not much better, since with them words are not prompted by sufficient knowledge or judgment to be of great service. Further, the wilfulness, dislikes, fear and agitation of the child are impediments which must be overcome before a satisfactory examina- tion can be made, and which will often tax the skill and patience of the physician to the utmost in the over- coming. Another source of difficulty lies in the activity of growth and development in infants, which renders them liable to be affected by slight causes, and makes disease sudden in its attack, short in its course and intense in its symptoms. The rapid development of the nervous system especially leads to confusion, since it binds every portion of the frame in a sympathy so close that an affection of a single part may cause marked general disturbance, and local symp- toms are often reflected, directing attention to organs very distant from those really diseased. Finally, the extreme ex- citability of the nervous system of healthy children often causes a trifling illness to assume an aspect of the greatest gravity, while, on the contrary, the depression of nervous sensibility that attends chronic wasting diseases so obscures the symptoms that a dangerous intercurrent affection may appear trifling or remain altogether latent. The plan of conducting the clinical investigation in child- ren differs materially from the method adopted in adults. It is best to proceed in three regular stages, as follows : ist. Questioning the attendants ; 2d. Inspecting the child ; 3d. Physical examination. 1. Questioning the Attendants. When the patient is under eight or ten years of age, the only way of obtaining a knowledge of the previous history and of what may occur between visits, is carefully to ques- THE INVESTIGATION OF DISEASE. 1 9 tion the mother or nurse. The account must be patiently elicited and listened to, and credited with due reference to the narrator's intelligence. It is well never entirely to dis- credit a statement without good reason, for many women, though weak and foolish in other respects, are excellent observers when their powers are guided by affection. Be- sides, being thoroughly acquainted with their children's habits and dispositions, they will often detect deviations from health that the physician might overlook entirely. This part of the examination, particularly when the acquaintance and good will of the child has not previously been obtained, should, if possible, be made before entering the sick-room. By taking this precaution the agitation produced by the pro- longed presence of a stranger, and its consequent trouble and delay, will be avoided to a great degree. As there are certain points about which it is always necessary to be informed, the adoption of a definite order of questioning is advisable. The family history as far back as the parents should first be ascertained. Inquiry being chiefly directed to the detec- tion of chronic maladies and transmissible diseases, as tuber- culosis and syphilis. If any deaths have occurred, their causation should be investigated, and an inquiry into the occurrence, or the reverse, of previous still-births is often important. Next, an outline of the child's life from birth up to the date of the illness in question must be obtained. This should include the following items : The manner of feed- ing during infancy ; whether at the breast, or from a bottle, and if the latter, whether cow's milk, condensed milk or the farinacea have formed the basis of the diet. The date of commencement and the regularity of dentition. The gene- ral state of health in regard to strength, or weakness and 20 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. liability to illness. The time of occurrence and the nature of any prominent attack of illness, especially of the eruptive fevers. Whether vaccination has been performed or no. The hygienic surroundings ; for instance the healthfulness of the locality of residence, the sort of house and room occu- pied — if large, well ventilated, light and dry or the reverse, and the character of the clothing and food. In older child- ren, if at school, the time devoted to study, and if at labor, the nature and the hours of work. After this it is necessary to fix the time the attack in hand began. The occurrence of some striking symptom, as convulsions or violent vomiting, often establishes this point beyond a doubt, but when there is any uncertainty the best plan is to question back, day by day, until a time is reached at which the child was perfectly well, and to date the onset from this period. The most com- mon of the general indications of commencing illness are disturbed sleep and irritability of temper. A perfectly well child sleeps quietly and continuously at night, and is never cross. Having determined, as nearly as possible, the exact time of onset, the next step is to learn the mode of attack and the symptoms and course of the disease prior to the first visit. The questions now must be general, never leading. They must be sufficiently exhaustive to touch upon all the functions of the body, and when a trail is started it must be patiently followed to the end. Alterations in sleep, bodily strength, surface temperature, appetite, digestion, urine elimi- nation, respiration and so on, must be sought for, and the account of such deviations from the normal state as vomit- ing, diarrhoea or cough, will suggest further questions as well as point out the path to be followed in the future examination. THE INVESTIGATION OF DISEASE. 21 This portion of the investigation is closed by an inquiry into the treatment that may have been already adopted. 2. Inspecting the Child. When the eye and ear of the physician are trained to their work, valuable information can be obtained by simply looking at an ill child and listening to its cry or spoken words. Even while the child is lying asleep or sitting quietly in the nurse's lap many facts may be learned, but this portion of the examination is never complete without an inspection of the naked body. The points thus ascer- tained consist in alterations in the expression of the face, in decubitus, in the appearances of the body and so on, and may be designated the features of disease. The relative position of the observer and patient during inspection is of importance. If possible the former should stand with his back to, and the latter be so placed that his face is toward, a window or lamp. The light must never be strong enough to dazzle when the countenance is the object of inspection, as this causes distortion of the features. For convenience, the features of disease will be studied under different headings, and since to appreciate them it is necessary to have a knowledge of the healthy aspect, both the normal and abnormal appearances will be described. Face. — The face of a healthy, sleeping child wears an expression of perfect repose. The eyelids are completely closed, the lips slightly parted, and while a faint sound of regular breathing may be heard, there is no perceptible movement of the nostrils. Incomplete closure of the lids with more or less exposure of the whites of the eyes is noted when sleep is rendered unsound by moderate pain and during the course of all acute and chronic diseases, particularly when they assume a grave type. Twitching of 22 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. the lids heralds the approach of a convulsion, and at such times, too, there is often oscillation of the eyeballs, or squinting. A marked smile, due to contraction of the muscles about the mouth, signifies abdominal pain or colic, and pursing out of the lips and chewing motions of the jaw, gastro-intestinal irritation. Dilatation of the alae nasi, with or without noisy breathing, points to embarrassed res- piration, the result of extensive bronchial catarrh, pneumonia or pleurisy with effusion. When awake and passive the healthy infant's face has a look of wondering observation of whatever is going on about it. As age advances the expression of intelligence increases, and every one is familiar with the bright, round, happy face of perfect childhood, so indicative of careless contentment, and so mobile in response to emotions. The picture is altered by the onset of any illness, the change being in proportion to the severity of the attack. An expression of anxiety or of suffering appears, or the features become pinched and lines are seen about the eyes and mouth. Pain most of all sets its mark upon the coun- tenance, and by noting the feature affected it is often pos- sible to fix the seat of serious disease. Thus, contraction of the brows denotes pain in the head ; sharpness of the nos- trils, pain in the chest ; and a drawing of the upper lip, pain in the abdomen. As a rule, the upper third of the face is modified in expression in affections of the brain, the middle third in diseases of the chest, and the lower third in lesions of the abdominal viscera. M. Jadelot has drawn attention to certain furrows that appear on the face in serious cases, and to the indications that these afford as to the part of the body to be further examined. There are three sets of furrows. First, the oculo-zygomatic, beginning at the inner canthus of the eye THE INVESTIGATION OF DISEASE. 23 and passing outward beneath the lower lid, to be lost a little below the most prominent portion of the cheek. This points to primary or secondary disorder of the cerebro- nervous system. Second, the nasal, starts above the ala of the nose, and, passing downward, forms a semicircle around the angle of the mouth. This may be associated with another line, the genal, which extends from its middle almost to the malar bone. These indicate disease of the gastro-intestinal tract, or other abdominal viscera. Third, the labial, commencing at the angle of the mouth and run- ning outward, to be lost in the lower part of the face. This furrow is more shallow than the others. It directs atten- tion to the lungs. These furrows are often present, and when met with are worthy of consideration, but their con- stancy and value have been over-estimated by their dis- coverer. Puffiness of the eyelids and a fulness of the bridge of the nose, indicate dropsy and should direct attention to the kidneys as the seat of disease. Each of the two promi- nent diatheses is distinguished by a peculiar physiognomy. When there is a tuberculous tendency the face is oval and the features delicate; the hair is fine and silky; the skin smooth and transparent ; the temporal veins are visible ; the eyelashes are long and curving, the irides large and deep-colored and the sclerotics pearly white or bluish ; finally, a growth of fine hair is often noticeable on the temples and in front of the ears. The general expression is most intelligent. In the strumous diathesis, on the con- trary, the face is round and heavy ; the complexion doughy ; the upper lip swollen ; the nostrils wide and the alse of the nose thick; the eyelids are thickened and reddened at their edges ; the hair coarse, and the lymphatic glands of the neck enlarged. 24 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. A marked disfigurement of the face may indicate one of several diseases, according to its character. For example, broadness of the bridge of the nose, or complete flatness at this point, is significant of constitutional syphilis. A large, square head and projecting forehead with a face of natural size or smaller, shows that the child has suffered from rickets. An immense globular head, overhanging forehead, and diminutive face with eyeballs projected down- ward and irides almost concealed by the lower lids, are pathognomonic signs of chronic hydrocephalus. Decubitus. — The complete repose depicted on the coun- tenance of a sleeping child when free from illness is shown also by the posture of the body. The head lies easy on the pillow, the trunk rests on the side slightly inclined backward, the limbs assume various but always most graceful attitudes, and no movement is observable but the gentle rise and fall of the abdomen in respiration. In the waking state the child, after early infancy, is rarely still. The movements of the arms, at first awkward, soon become full of purpose as he reaches to handle and examine various objects about him. The legs are idle longer, though these, too, soon begin to be moved about with method, feeling the ground, in preparation, as it were, for creeping and walking. With the onset of disease the scene changes. In acute attacks attended with pain, sleep is no longer restful. The infant is content only when rocked, fondled or " walked " in the nurse's arms. The older child tosses about uneasily in bed, or demands a constant change from the bed to the lap. During the waking hours the movements are purposeless, quick and impatient, the position is constantly shifted and frequent whining complaints are made. As a contrast to this condition of jactation, at the beginning of the specific THE INVESTIGATION OF DISEASE. 2$ fevers, children often lie for hours quiet and drowsy upon the bed or lap. In chronic affections attended with debility, the move- ments become slow and languid, and in stupor and coma there is perfect stillness and immobility. There are certain positions and gestures which have especial significance. Sleeping with the head thrown back, and the mouth open, is a frequent accompaniment of chronic enlargement of the tonsils. A tendency to " sleep high," that is with the head and shoulders elevated by the pillow, indicates im- paired pulmonary or cardiac function. So, too, does an upright position in the nurse's arms, with the chest against her breast and the head hanging over her shoulder — a pos- ture assumed by young children. " Sleeping cool," namely, resting only after all the bed clothing has been kicked off, is an early symptom of rickets. The position termed "en chien de fusil" is a symptom of the advanced stages of cerebral disease, especially tubercu- lar meningitis. The child lies upon one side, with the head stretched far back, the arms pressed close to the sides and folded across the chest, the thighs drawn up toward the abdomen, the legs flexed on the thighs and the feet crossed. Restless movements of the head or boring of the head into the pillow also point to cerebral disease. When there is an evident desire to retain one position, as on the back or one side, together with short, quick breath- ing, some inflammatory change in the respiratory or abdomi- nal organs may be suspected. Persistent lying on the face is an evidence of photophobia. Of the gestures, the frequent carrying of the hand to the head, ear or mouth indicates headache, earache or the pain 26 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. of dentition respectively, and constant rubbing of the nose is a feature of gastro-intestinal irritation. If the thumbs be drawn into the palms of the hands, and the fingers tightly clasped over them, or if the toes be strongly flexed or extended, a convulsion may be expected. The presence of clonic contractions of the muscles, with unconsciousness, indicates, of course, a convulsion ; while irregular, badly coordinated, jerky .movements — conscious- ness being retained — attend chorea. In infants the existence of colic is shown by repeated extension and retraction of the legs, clenching of the hands into fists, flexion and extension of the forearms, and a writhing movement of the trunk. The fact of one limb remaining passive while the others are actively moved about, naturally suggests motor paralysis. The Skin. — In the new-born infant the color of the skin varies from a deep to a light shade of red. After the lapse of a week this redness fades away, leaving the surface yellowish-white. Sometimes the yellow hue is so deep that it might readily be mistaken for jaundice were it not for the whiteness of the conjunctivae, and the absence of disordered digestion and other symptoms of ill-health. Usually in a fortnight all discoloration disappears, and the skin assumes its typical appearance. Allowing for the natural variations in complexion, the skin of a healthy child is beautifully white, transparent and velvety. The cheeks, palms of the hands and soles of the feet have a delicate pink color, and the general surface is rosy in a warm atmosphere, marbled with faint blue spots or lines, in a cool one. As age ad- vances the coloring becomes more pronounced, and until the completion of childhood the complexion is much fresher than in adult life. THE INVESTIGATION OF DISEASE. 2J In the inspection alterations of the skin of the face are chiefly noticeable. Lividity of the eyelids and lips is a sign of imperfect aeration of the blood and points to pulmonary or cardiac disease. Marked blueness of the whole face is a symptom of morbus cceruleus, and indicates a congenital malformation of the heart. On the other hand, a faint purple tint of the eyelids and around the mouth shows weak circulation merely, or, more frequently, deranged di- gestion. A decided yellow hue of the skin and conjunctivae is seen in jaundice ; an earthy tinge of the face in chronic intestinal diseases ; a waxy pallor in renal diseases, and paleness in any acute or chronic affection attended with exhaustion. Brownish-yellow discoloration of the forehead is signifi- cant of inherited syphilis ; a bright, circumscribed flush on one or both cheeks, of inflammation of the lungs or pleura, or of gastro-intestinal catarrh, according to its occurrence with or without an elevated surface temperature. The cutaneous lesions of certain of the eruptive fevers appear first upon the face ; each of these has its special char- acteristics. An eruption of herpetic vesicles on the lips may be mentioned as present both in pneumonia and in malarial fevers. Some information may be obtained from the hands. Slight want of proper aeration of the blood is shown by blueness of the finger nails, a greater degree, by cyanosis of the whole hand. Deformity of the nails is a symptom of syphilis ; clubbing of the finger tips of chronic lung disease ; and redness, swelling and suppuration about the nails of struma. The dropsy of scarlatinal nephritis causes a pufjfi- ness and cushiony appearance of the dorsum of the hands. Often, too, in this condition, the finger ends are glossy, as if smeared with oil, and there is an exfoliation of the epidermis 28 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. about the nails. The last two symptoms frequently serve to confirm a retrospective diagnosis of scarlet fever. Mode of Drinking. — By watching a child taking the breast or bottle, some knowledge can be obtained of the condition both of the mouth and throat, and of the respira- tory organs. If there be any soreness of the mouth the nipple is held only for a moment, and then dropped with a cry of pain. When the throat is affected deglutition is performed in a gulping manner, an expression of pain passes over the face, and no more efforts are made than required to satisfy the first pangs of hunger. Under similar circumstances older children drink little and refuse solid food entirely. An infant suffering from the oppression of pneumonia or severe bronchitis, seizes the nipple with avidity, swallows quickly several times, and then pauses for breath. In older patients the act of drinking, which should be continuous, is interrupted in the same way. If the finger be put into the mouth of a healthy baby it will be vigorously sucked for some little time. The diminution of the act of suction during a severe illness is a sign of danger ; its reestablishment a good omen. In con- ditions of stupor and coma it is noticeably absent. The Cry. — The vocal sound, termed crying, is the chief if not the only means that the young infant possesses of indicating his displeasure, discomfort or suffering. Even long after the powers of speech have been developed, the cry continues to be the main channel of complaint. It may be accepted, as a rule, that a healthy child never cries. Of course, some acute pain, as from a fall or accident or blow, will cause crying in the most healthy child, but the storm is quickly over. Nothing like frequent, peevish crying or fretfulness is compatible with health, consequently, when THE INVESTIGATION OF DISEASE. 20, this disposition exists, the cause must be looked for in some disease. Incessant, unappeasable crying is due to one of two causes, namely, earache or hunger, and the distinction may readily be made by putting the child to the breast or offer- ing a properly prepared bottle. The hydr encephalic cry, de- noting pain in the head, is a sudden, sharp and very loud shriek, occurring at intervals and audible at a considerable distance. Crying during an attack of coughing, or for a brief time afterwards, and attended with distortion of the features, indicates pneumonia. In acute pleuritis, the cry also accompanies the cough, but it is produced also by movements of the body and by pressure on the affected side. It is louder, indicative of greater suffering, and some- times most difficult to check. Intestinal pain causes cry- ing just before or after an evacuation of the bowels, and is associated with wriggling movements of the body and pel- vis, and with the eructation or passage of flatus. Con- ditions of general distress or malaise predispose to fits of fretful crying, the paroxysms being excited by any disturb- ing influence, or even by merely looking at the little sufferer. When the cry has a nasal tone, it indicates swelling of the mucous membrane of the nares, or other obstructing condition. Thickening and indistinctness occurs with pharyngeal affections. A loud, brazen cry is a precursor of spasmodic croup. Hoarseness points to a lesion of the laryngeal mucous membrane, either catarrhal or syphilitic in nature. In membranous croup, and in some cases of ex- treme exhaustion, the cry is faint and inaudible. Finally, in severe croupous pneumonia, in extensive pleural effusion and in rickets, ordinary disturbing causes are inoperative for the production of fits of crying, and there is a seeming 30 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. unwillingness to cry, on account of the action interfering with the respiratory function. The conditions of altered tone apply equally to the articu- late voice in children who are old enough to speak. The cough, too, must not be disregarded. Many of its characters correspond with the voice and cry. It is brazen in spasmodic croup, suppressed in true croup, hoarse in laryngeal catarrh, and so on. But it has certain features of its own. In bronchitis it is more or less paroxysmal, evidently dry in the early stages, loose and rattling as the catarrh " breaks up." In the painful pulmonary affections, pneumonia and pleurisy, it is choked back, and whenever it occurs, an expression of pain passes like a cloud over the face. In pertussis, the peculiar spasmodic cough is the pathognomonic symptom, and when once heard, immedi- ately stamps the case. Cough is always unproductive, that is, unattended by expectoration, in children under seven years of age. The formation of tears rarely begins before the third or fourth month of life. Subsequently, an alteration in this secretion may be of aid in forecasting the result of disease. The prognosis is bad when the tears become suppressed ; good when the secretion continues during an illness, or when it reappears after being suppressed. There are three other sources of information which can and should be investigated before proceeding to the physi- cal examination, although, strictly speaking, they do not come under the head of inspection of the child. These are the characters of the fsecal evacuations, of the urine, and of the material ejected by vomiting. The FAECAL Evacuations. — The daily number of evacua- tions natural for a child varies greatly with its age. For the first six weeks there should be three or four stools THE INVESTIGATION OF DISEASE. 3 1 every twenty-four hours. After this time up to the end of the second year, two movements a day is the normal average. Subsequently, the frequency of defecation is the same as in adults — once per diem — though two or three movements in the same interval often occur, especially after over-feeding or after eating food difficult of digestion, and must be looked upon as conservative rather than as the evidence of ill-health. During the first period the stools have the consistence of thick soup, are yellowish-white, or orange-yellow in color, with sometimes a tinge of green, have a faint faecal, slightly sour odor, and are acid in reaction. In the second, they are mushy or imperfectly./^;?^, of uniform consistence through- out, brownish-yellow in color, and have a more faecal odor. The last two characters become more marked as additions are made to the diet. After the completion of the first dentition the motions have the same appearance as in adult life, they are formed, and brownish in color, with a decided faecal odor. Many alterations occur in disease. The frequency of the movements may be increased, constituting diarrhoea, or lessened, constituting constipation. In the former condition the consistency is diminished, in the latter increased. In- stead of being uniform throughout, the stool may be mixed, partly liquid partly solid, indicating imperfect digestion, and curds of milk or pieces of undigested solid food may be mingled with the mass. Flaky, yellowish or yellowish- green evacuations, containing whitish, cheesy lumps, are also met with in cases of indigestion. Scanty, scybalous stools, dark brown or black in color, and mixed with mucus, are characteristic of intestinal catarrh. Doughy, grayish, or clay-colored motions show a deficiency of bile. An intermixture of blood, altered blood clots, and shreds of 32 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. mucous membrane, indicate some breach of continuity in the intestinal lining, such as occurs in follicular enteritis, typhoid fever, dysentery and tubercular disease. Watery, almost odorless stools occur in the latter stages of entero- colitis ; most offensive, carrion-like motions, in both catarrhal and tuberculous ulceration of the intestines, and sour- smelling evacuations in the diarrhoea of suck- lings. The discovery of worms or their ova in the stools is the certain evidence of the existence of intestinal para- sites. This mere outline of the changes that may take place will serve to show how much may be learned from the stools, and the importance of making a personal examina- tion of them. The Urine. — It is impossible to make a definite state- ment as to the number of times the urine is voided by a healthy infant, in each twenty-four hours. In any given case the frequency will differ very much from day to day, depending upon the temperature of the surrounding air, the amount of moisture that it contains, and so on. Sometimes it will be necessary to change the diaper every hour during the day and three or four times at night. Again it may remain dry for six, eight, or even ten hours. Neither condition indicates disease, and between the two extremes there is a wide range of variation. Should the urine not be passed for twelve hours or more, a careful examination should be made to discover and remedy retention. As the child grows older the frequency diminishes, and at the age of three years the number of voidings will be reduced to six or eight during the waking hours, and perhaps one at night. When the desire does arise during sleep, the child, if in a normal state, wakes up and demands the chamber, and never passes urine unconsciously. Wetting THE INVESTIGATION OF DISEASE. 33 the bed, therefore, or the involuntary passage of the urine during sleep, is indicative of an abnormal condition and re- quires investigation.* The urine of an infant, while it wets, should not stain the diaper. In certain cases of mal-digestion it becomes very concentrated and high-colored, and gives a light yellow tinge to the napkin. When the stain is decidedly yellow, jaundice is indicated, and other symptoms of this condition should be looked for. In older children a high-colored urine, and one which deposits a whitish or pinkish sediment on standing, is symptomatic of acute digestive disorder, either catarrhal in its nature, or secondary to some acute febrile affection. A smoky, blackish hue, looking as if there had been an admix- ture of soot, is pathognomonic of acute scarlatinal nephritis ; in this state, too, there is a great diminution in the amount passed. Painful micturition points to inflammation of the urethra, a narrow preputial orifice, a highly acid condition of the excretion, or stone in the bladder. Chemical tests and microscopical examination reveal many alterations in the urine of children. These have the same significance as analogous changes in the case of adults. Vomiting. — Both vomiting and regurgitation are of ready production and frequent occurrence in infancy, on account of the vertical position and cylindrical outline of the stomach at this period of life. Babies suckled at an abundant breast, and who are in the * From a few observations, I am led to believe that the quantity of urine voided by healthy children from the fourth to the seventh years is not nearly so large as supposed ; eighteen to twenty ounces being the average in several cases in which I have lately made measurements. 3 34 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. best possible state of health, often vomit habitually. In these cases, the supply of food being large, the infant as it lies at the breast is apt to draw more than it needs and more than it can digest. The stomach rids itself of this over-supply by an act which more nearly resembles regur- gitation than vomiting, and which must be regarded as an evidence of health rather than the reverse. There is no violent effort or retching, the material ejected is the breast milk alone, either entirely unaltered or slightly curdled, and there are no symptoms of nausea, such as paleness, languor and faintness. In older children, vomiting may also occur after the stomach has been overladen. If the act be followed by relief from a feeling of general distress, headache and epi- gastric pain, it must not be regarded as a symptom of dis- ease. Vomiting attended with the train of symptoms embraced under the term nausea, is not a pathognomonic symptom. It may indicate disease of the stomach, of the intestines, of the lungs and pleura, and of the brain, or it may be a pro- drome of one of the eruptive fevers. Which condition is present can only be determined by watching the case, and by a careful study of the rational symptoms and physical signs. The character of the ejecta is more definite. For in- stance, the expulsion of mucus is a symptom of gastric catarrh. The regurgitation of mouthfuls of curdled milk, partially digested food and liquid so sour that it causes a grimace to pass over the face, is an indication of dyspepsia with fermentation and the formation of acid. The appear- ance of lumbricoid worms in the vomit, a not infrequent occurrence, shows conclusively the existence of these para- sites in the alimentary canal. THE INVESTIGATION OF DISEASE. 35 3. Physical Examination. The methods of physical exploration in children are identical with those employed in adults, and the results do not differ in kind. Since, however, the object of exploration is to elicit the greatest amount of information with the least possible disturbance of the child, and since this very dis- turbance alters the character of some of the information obtained, it is well to adopt a somewhat different order of examination, and one which at first sight may seem irregu- lar. Thus it is best first, to ascertain the character of the respiration and the pulse, then to strip the body to determine the degree of muscular development and the condition of the skin, next, to investigate the physical condition of the lungs, heart and abdominal organs, and last of all to exam- ine the mouth and throat. In this order, then, the normal, as well as the more prominent abnormal features connected with the different organs will be considered. The Respiration. — In children the respiration is chiefly abdominal in type, irrespective of sex, and it is not until just before the age of puberty that the movements in the female change, becoming superior costal. Consequently, in estimating the number of movements per minute, it is best to place the fingers lightly on the epigastrium. The count should always be made by the watch, and the most con- venient time for the observation is while the child sleeps. Soon after birth the number of movements per minute is 44, between the ages of two months and two years, 35, and between two and twelve years, 23. During sleep the fre- quency is reduced about twenty per cent. Children under two years, while awake, breathe unevenly and irregularly; there are frequent pauses followed by hurry and precipitation, and some of the movements are shallow, others deep. In sleep there is greater regularity. After the 6 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. second year the movements become steady and even, like those of adults. All children, however, but particularly the very young, are subject to a great increase in the rapidity of respiration under the excitement of muscular movement and mental emotion. Accelerated breathing occurs during the course of dis- eases attended by severe febrile symptoms, such as the acute exanthemata, the inflammatory and other affections of the thoracic viscera, and in rickets. Acute pulmonary lesions are especially characterized by this alteration, and the more the breathing area is lessened the greater is the increase. Thus, in pneumonia, 60, 80 or 100 movements a minute are not at all unusual. To speak broadly, rapid breathing may be caused by an elevation in the body temperature, by an interference with the blood aeration and by thoracic or ab- dominal pain. As the increase in frequency may be unattended by any apparent effort, or true dyspnoea, it is well to make a rule of counting the respirations in every case in which the diag- nosis is at all doubtful. Diminished frequency, the movements being reduced to 16, 12, or even 8 in the minute, is noted in certain brain affections, as in chronic hydrocephalus, and in the later stages of tubercular meningitis. In such cases the rhythm may be greatly altered — a tidal form being assumed, in which the breathing ebbs and flows, beginning with an act which is scarcely perceptible or audible, gradually growing deeper until a full, noisy respiration is made, and then slowly subsiding into a period of absolute quiet, variable in its du- ration. This is termed Cheyne-Stokes' respiration. Another form of breathing, in which the alteration is mainly in the rhythm, is termed expiratory respiration. In the normal act, inspiration is immediately succeeded by THE INVESTIGATION OF DISEASE. 37 expiration, and between the latter and the next inspiration there is a period of silence or rest. Expiratory respiration, on the contrary, is characterized by the pause coming be- tween inspiration and expiration, the expiratory effort, always very marked, being immediately succeeded by the inspiratory. This alteration occurs most frequently in young children, and is an evidence of dangerous pulmonary embarrassment. Perfectly healthy children breathe through the nose, and so softly that it is necessary to place the ear close to the face to hear the breezy sound of the ingoing and outgoing air. A dry, hissing sound, or a moist sound of snuffling indicates partial obstruction of the nasal passages ; oral res- piration, complete occlusion. Difficult breathing with pro- longed inspiration — inspiratory dyspnoea — shows an impedi- ment to the entrance of air into the lungs and indicates laryngeal obstruction, due, most commonly, to spasm or to the formation of false membrane. In such cases the inspira- tory act is also attended by a loud, piping, or rasping sound. Labored breathing with prolonged wheezing respiration — expiratory dysp7tcea * — occurs when the escape of air is impeded. The causative lesion is to be found, not in the larynx, but in the lungs. It may be a bronchial catarrh with excessive secretion, an emphysematous condition of the air vesicles, or asthma. In both forms of dyspnoea the movements are slow as well as difficult, and a combination of the two forms is met with in cases of marked laryngeal stenosis. Yawning, one of the modifications of the respiratory act, if it recur frequently, denotes great failure of the vital powers and is an unfavorable prognostic element. * I prefer to limit the term dyspnoea to difficult or labored respiration, and not to extend it to include simple accelerated breathing. 38 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. The Pulse. — To obtain any reliable data from the pulse it must be felt while the patient is perfectly quiet. The best time is during sleep, but if the child cannot be caught in this condition, advantage may be taken of its pla- cidity while nursing at the breast, feeding from a bottle, or amused by a toy or book. With very young infants it is sometimes impossible to feel the beat of the radial artery, and it is necessary to ascertain the frequency of the pulse by directly ausculting the heart. After the second month palpation of the pulse at the wrist in the ordinary way pre- sents no difficulties. The child's pulse differs from the adult's by being much more frequent, more irregular, and more irritable. The frequency, or the number of beats per minute, varies with the age. The following is the average rate : — From birth, to the 2d month, 160 to 130. From the 2d to the 6th month, 130 to 120. " " 6th " 1 2th " 120 to no. u u Ist « 3d year, no to 100. " " 3d " 5th " 100 to 90. " " 5th " ioth " 90 to 80. " " ioth " 12th " 80 to 70. These figures represent the pulse in a waking but passive state. During sleep the frequency is less. Thus between the second and ninth years there are about sixteen beats less per minute while asleep than when awake; between the ninth and twelfth years, eight less ; and between the twelfth and fifteenth years only two less. Below the age of two years the disparity is even greater. The irregularity of the pulse in childhood is confined to an alteration of the rhythm. It is most marked in infants and is greatest during sleep, when the pulse is slowest. The feature of irritability, that is, the facility with which THE INVESTIGATION OF DISEASE. 39 its frequency is increased by muscular activity and mental excitement, is greater in proportion to the youth of the child. A rise of 20, 30 or even 40 beats a minute is not un- common in early infancy under the excitement of the slight- est effort or disturbance. On account of these wide variations in health, little symp- tomatic meaning need be attached to alterations of the rhythm and frequency while unassociated with other ab- normal features. When so associated they become import- ant in diagnosis. Increased frequency is a constant attendant of the febrile state. The extent of the increase corresponds with the de- gree of elevation of the temperature, though the pulse curve always runs higher than the temperature curve. The more frequent the pulse the higher the fever, is the rule, but in estimating the prognostic value of the increase, the law of the fever in question must be taken into consideration. For example, in scarlatina a pulse of 160 is usual and not in- dicative of special gravity, whereas in measles the same degree of acceleration would be abnormal and show great danger. Jaundice and parenchymatous nephritis are accompanied by a diminution of the rate. Irregularity is met with in diseases of the brain and heart, and sometimes in nervous and anaemic children. The Temperature must be estimated before removing the clothing. No reliable result can be obtained with- out the use of an accurate clinical thermometer. The instrument is usually placed in the rectum* of the infant and young child ; in the axilla of one old enough to understand the importance of keeping the arm in a proper attitude. It should remain in position at least five minutes. * The rectal temperature is normally at least i° higher than the axillary. 40 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. During the first week of life the temperature fluctuates considerably. After that the puerile norme — 98. 5 ° to 99°F. — is established, but until the fourth or fifth month it is greatly influenced by healthy causes of variation ; the fluc- tuations ranging between .9° and 3. 6°. By the fifth month regular morning and evening oscillations begin to be noticeable, and certain definite laws are followed. There is a fall in the evening of i° or 2°. The greatest fall occurs between 7 and 9 p.m. and the minimum is reached at, or be- fore, 2 a.m. After 2 a.m. there is a gradual rise, the maxi- mum being reached between 8 and 10 a.m. Throughout the day the oscillation is trifling. These variations are inde- pendent of eating and sleeping. In disease there may be either a rise above, or a fall below, the normal standard. Fever is always associated with an elevation of the tem- perature. Rapid and transient rises attend slight catarrhs and passing indigestions ; prolonged rises, inflammatory and essential fevers. The degree of elevation marks the type of the pyrexia. This is moderate when the mercury stands at 102 , severe at 104 or 105 °, and very grave above 107 . The duration of the elevation and the pecu- liar range of the oscillations — for there are oscillations in disease as well as in health — determine the nature of the fever. The febrile oscillations differ from the healthy in that the lowest marking is noticed in the morning, the high- est in the evening. Variations in the typical range of any given fever are important prognostic omens— a sudden fall of the temperature, together with improvement in the general symptoms, indicates the beginning of convales- cence — a similar fall, with an increase of the general symp- toms, is a precursor of death. When the morning tem- perature is equal to that of the preceding evening, there is THE INVESTIGATION OF DISEASE. 4 1 great danger; if higher, greater danger still. Marked remission in continued fevers is generally a forerunner of convalescence. Abnormal depression of temperature is occasioned by- hemorrhage and by the loss of fluids in cholera infantum or entero-colitis. It is also met with in anaemia, in atrophy from insufficient nourishment, in diseases of the heart and lungs attended by imperfect blood aeration, and it con- stantly attends collapse and the death agony. A maintained temperature of 97 ° is dangerous in children, and for every degree of reduction below this point, the risk to life is more than proportionately increased. While the physician must use the thermometer, to insure accuracy, he can, by placing the hand on the skin, detect gross differences of temperature. Reductions are best appreciated by touching the nose and extremities, while increased heat is most readily felt at the back of the head and in the palms of the hands. Having determined the character of the respiration, pulse and temperature, the next step in the physical examination is to strip the child, in order to ascertain his general devel- opment, the condition of his skin, and so on. The General Development. — The healthy child under two years of age is plump of body and round of limb with well-developed fat cushions and firm flesh, and with the head and abdomen large in proportion to the rest of the frame. As age advances, the figure gradually assumes the characteristics of adolescence. To be robust, the newly-born child must have a certain average size and weight. Subsequently, under normal cir- cumstances, there is a regular rate of increase in both of these respects. At birth the length is about 16 inches. Growth is quickest in the first week of life. In the first 42 DISEASES OF DIGESTIVE ORGANS IN. CHILDREN. year there is an increase of from 5 to 6^ inches; in the second, from 2 2 / l to 3^ inches; in the third, from 2% to 2^3 inches; in the fourth, about 2 inches; and from the fifth to the sixteenth years the annual growth amounts to from 1^ to 2 inches. The average weight at birth is from 6 to 8 pounds. The daily increase in weight should range from y± to y x of an ounce. With these data it is quite possible to estimate what should be the normal size and weight of a child at any age. Consequently, if, on being measured and weighed, he be found to fall short of the normal standard, it is proper to infer the existence of some fault in the nutritive processes. A conclusion still further borne out by a want of rotundity of outline and by flabbiness of the muscles. The age at which the child sits erect, at which it walks, and at which the anterior fontanelle becomes ossified, are points closely connected with the subject of development and nutrition. For some time after birth, the child, if noticed while si- ting upon the lap, will be observed to hold the head and shoulders forward or to " stoop " a little ; the spine, from the cervical region to the sacrum, forming a continuous curve with the convexity directed backward. Toward the end of the eighth month the position begins to become more erect, and in a few weeks is perfectly so, the spine assuming an almost perpendicular line. Any marked delay in this change indicates general debility. At the end of the fourteenth month the child should be able to walk alone. The spine then assumes the S-like curve seen in healthy adults. A delay in walking may be due to systemic weakness or to infantile paralysis affecting one or both legs. If the walking be done on the toes chiefly, if the gait be limping, and especially if knee-pain be com- THE INVESTIGATION OF DISEASE. 43 plained of, and manipulation of the limbs causes suffering, the chances are that hip-joint disease is commencing. The anterior fontanelle should be ossified or completely closed at some period between the fifteenth and twentieth months. The closure is much retarded in rickets, which is preeminently a disease of mal-nutrition. Hydrocephalus and constitutional syphilis have a like effect. In a state of health, the opening, while still membranous, is level with the cranial bones or very slightly depressed. Condi- tions of systemic exhaustion cause marked sinking, and this depression is one of the best indications of the neces- sity of stimulation. Bulging of the fontanelle is a symptom of chronic hydrocephalus. Conditions of the Skin. — The normal color of the in- tegument, and the alterations produced by disease, have already been studied. The other characters possessed by the skin of a healthy child are, a velvety smoothness and softness, a scarcely perceptible moisture, and a great de- gree of elasticity. Disease causes modifications in texture, in moisture, and in elasticity, and leads to the appearance of various erup- tions and to cedema. Mucous disease is attended with a dry, harsh skin, which is muddy in color, and covered, especially on the extensor surfaces of the arms and legs, by a thick layer of exfoliating epidermis. Chronic abdominal affections, particularly tu- berculosis of the intestines and mesenteric glands, lead to harshness, acridity, scurfiness, and a wrinkled appearance of the skin covering the abdomen and thorax, with enlarge- ment of the superficial abdominal veins. Protracted diarrhoea, and still more, vomiting and diar- rhoea, cause absorption of the subcutaneous fat and wasting of the muscles. The skin becomes too large for the body, 44 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. is dry, harsh, discolored, and so inelastic that it falls into wrinkles over the joints when the limbs are moved, and if pinched up retains the fold for a long time. The condition of general atrophy popularly known as " marasmus," presents these features most strikingly. Dryness is a concomitant of the febrile state ; excessive moisture, of prostration of the vital forces and collapse. Eruptions appear upon the integument, in the skin dis- eases proper, in the exanthemata, in constitutional syphilis and in certain digestive disorders. CEdema of the subcutaneous connective tissue may be due to affections of the heart, liver or kidneys. The cardiac variety usually shows itself first in the feet ; the renal, in the eyelids ; the hepatic, in the feet and legs, secondarily to ascites. While examining the surface it is well to look for enlarge- ment of the superficial lymphatic glands and swelling of the joints. The former occurs in scrofula and syphilis ; the latter in rheumatism. Examination of the Abdomen. — To examine this por- tion of the body the child, still stripped, must be placed on its back, upon the bed or nurse's lap. Quiet is most import- ant, since struggling and crying are attended by such con- traction of the abdominal muscles and rigidity of the walls that little can then be learned of the condition of the con- tained organs. The methods of investigation are those ordinarily employed in physical examination. Palpation or percussion should never be made with cold hands. The abdomen of a healthy child is somewhat prominent, uniformly soft, yielding, and painless to the touch, and to percussion gives a tympanitic sound, varying in tone accord- ing to the position percussed. The tympanitic note being lowest in pitch over the epigastric and left hypochondriac THE INVESTIGATION OF DISEASE. 45 regions, the seat of the stomach ; highest, over the umbili- cal region, the position of the small intestine. In disease inspection reveals any disproportion in the size or form of the abdomen, the state of the integuments, of the superficial veins, and of the umbilicus. Palpation shows the temperature, pliability, moisture and tension of the walls, and the presence or absence of tenderness, of fluctua- tion, and of enlargement of the mesenteric glands, and other solid viscera. Percussion serves to demonstrate the nature of enlargements, whether due to accumulation of gas or liquid, or to solid growths. By it, also, the outline and size of the liver and spleen may be determined. Distension of the abdomen is, in the vast majority of in- stances, due to flatulence. In children reduced by chronic disease the bowels are usually deranged, the food is badly digested, and the gases set free by the decomposition of the starchy foods accumulate, owing to feebleness of the intes- tinal walls, and give rise to much swelling and discomfort. Over such an abdomen the skin feels tense, the umbilicus is level or slightly prominent, there is no tenderness on pres- sure, and percussion is markedly tympanitic. This simple cause of enlargement must be remembered, for a distended abdomen in a wasting child is often falsely attributed to caseation of the mesenteric glands. The latter disease is uncommon at any age, extremely rare under three years, and, moreover, is by no means uniformly attended by distension. On the contrary, unless the glandular disease is excessive, retraction is the rule. When distension does exist it depends upon associated intestinal disorder, and is merely an accidental complication. The only pathognomonic sign is the detection of the tumor caused by the enlarged glands. This is situated in the umbilical region, and is firm, lobulated and slightly tender to the touch. It is most readily detected 4.6 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. by gently grasping the abdomen on either side with the hands and slowly bringing the fingers together toward the median line. Percussion over the tumor yields a dull, tym- panitic sound. Whenever there is associated flatulence it is difficult or impossible to detect the tumor. Drum-like distension, with great tenderness, and muffled tympanitic percussion note occur in general peritonitis. Uniform distension, again, may be due to ascites depend- ing upon simple or tubercular peritonitis, kidney disease, or less commonly, disease of the liver. The abdomen is barrel- shaped, painless to the touch, and there is extended fluctua- tion. Percussion is dull over the position of the fluid, but in nearly every instance there is an area of tympany which changes its position ; moving always to the upper part of the abdomen, in reference to the posture of the patient. This variation is most important in the diagnosis. Localized distension may be traced to gaseous accumula- tion, to enlargement of the liver and spleen, to faecal accu- mulation, to circumscribed peritonitis, and to distension of the bladder. Collections of gas are always tympanitic on percussion. The extent of liver dulness is to be estimated by percus- sion. If the organ extend below the rib margin, the edge can usually be felt by laying the palm of the warmed hand flat upon the abdomen and making gentle pressure down- ward with the ends of the fingers. An enlarged spleen may be felt by placing the fingers of the right hand on the back, directly below the twelfth rib and outside of the lumbar muscles ; the fingers of the left, on the abdomen, directly opposite ; then bringing the hands toward one another. If the hands have been rightly ap- plied, and nothing is felt, the spleen may be considered to be normal in size. The fact that both the liver and spleen, THE INVESTIGATION OF DISEASE. 47 though still unenlarged, may be more readily felt than natural when pressed downward by the diaphragm, must not be overlooked. A faecal accumulation is distinguished by the absence of tenderness, by the oblong shape of the tumor, by the situa- tion, in the region of the transverse or descending colon,- to which its long axis corresponds, and by its shape being capable of some modification by pressure. Percussion over such a mass is dull. Distension of the bladder gives rise to a bulging tumor in the hypogastric region, which is elastic to the touch and dull on percussion. A shrunken or scaphoid condition of the abdomen is met with in serious brain affections, notably tubercular menin- gitis, also in cholera infantum, follicular enteritis and dysen- tery. Tenderness to pressure indicates inflammatory lesion of the intestines. The presence or absence of this sign in an infant can be determined by forcing the attention, by bring- ing it before a strong light, for instance, and then making pressure on the abdomen. If crying be produced, there is tenderness, if not, the reverse. Examination of the Chest. — The stethoscope and pleximeter are unnecessary in examining the lungs. In the case of the heart, the former may be occasionally required, to localize murmurs. When used, it is better to give the instrument to the child to handle and become familiar with, before application. The thoracic end must never be adjusted without being warmed. The quieter the patient the more complete and satisfactory will be the results of the exploration. Unfortunately, though, it is too often necessary for one to do the best possible in the midst of cries and struggling. However, by skilfully seizing op- 4o DISEASES OF DIGESTIVE ORGANS IN CHILDREN. portune moments, much reliable information may be gained. Aid is also derived from the fact that in serious lung affec- tions, as croupous pneumonia, the child is quiet from choice, crying interfering with the respiratory act, upon which his attention is concentrated. The steps of the examination are, first, inspection ; second, auscultation ; third, palpation ; and fourth, percussion. The reason for making the order different from that practiced in adults, is to place the most disturbing element last. Mensuration and succussion are infrequently resorted to in children. If required, they are best postponed until the end of the examination. Inspection. — The sitting posture, the child being stripped and in good light, is the best for this process. Note is to be taken of the shape of the chest, the character of the breath- ing, and the position of the apex beat of the heart. In the new-born baby, the chest is nearly circular in shape, the antero-posterior diameter being almost as great as the lateral. Later, it gradually becomes elliptical, the lateral diameter in time considerably exceeding the antero- posterior. The intercostal spaces are poorly marked, and the scapulae lie so close that their outline is scarcely per- ceptible. The circular shape of the chest allows of little lateral expansion, and for this reason the respiration is chiefly abdominal in type. Together with the movement of the abdominal walls, every act of inspiration is attended by a certain amount of recession of the lower part of the chest walls, the yielding ribs being forced inward by the pressure of the external air before they can be sufficiently supported by the expanding lung. The rise and fall of the cardiac apex can be seen, except when there is a great accu- mulation of fat, a short distance below and to the right of the left nipple. THE INVESTIGATION OF DISEASE. 49 Disease may alter all of these conditions. The tubercu- lous diathesis is characterized by a small chest, and one which has either the alar or the flat shape. In rickets the thorax becomes irregularly triangular in outline. Emphy- sema causes a barrel-shaped chest, with stooping shoulders and round back. Pleuritis with large effusion produces bulging of the affected side, and sometimes prominence of the intercostal spaces. After absorption has taken place there may be marked retraction, sinking of the interspaces, falling of the shoulders, and curvature of the spine toward the healthy side. Cessation of the costal respiratory movements indicates inflammation of the lung or pleura, or a large pleuritic effusion. Cessation of the abdominal play, inflammation of the peritoneum or of the intestines ; excessive ascites and gaseous accumulations produce the same effect. Rachitic softening of the ribs, and those diseases of the lungs and air passages which offer a direct obstacle to the entrance of air, are associated with a great increase in the normal recession of the lower portion of the chest on inspi- ration. In certain cases, a deep furrow appears across the chest, marking the upper borders of the abdominal viscera. The depth of the furrow indicates the degree of softening and of obstruction to the ingoing air. The position of the apex beat is altered by cardiac diseases, by pleuritis, and occasionally by gaseous disten- sion of the stomach. When the left ventricle is enlarged, it is shifted downward and to the left. Transmitted epi- gastric pulsation shows enlargement of the right ventricle. An extended impulse is not necessarily a sign of disease, since the chest-walls are so elastic in childhood that the normal impact of the apex is apt to affect a wide area. The effusion of pleurisy pushes the heart to the right or left, 4 50 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. while the retraction, after absorption or evacuation, draws it in one or other direction. The apex is pushed upward and to the left in gastric flatulence. Emphysema, by push- ing the heart away from the thoracic wall, diminishes or entirely hides the impulse. Auscultation. — With infants, the back of the chest is most conveniently ausculted when the child is held in the nurse's left arm, with his breast against hers, his chin rest- ing upon her left shoulder, his left arm around her neck, and his head kept in position by her disengaged hand. The front, when reclining on the back on a pillow. The sides, when sitting upright on the lap, first one arm and then the other being lifted up to allow the observer's ear to be applied. Older children may be made to take the same positions as adults. It is not sufficient to auscult the posterior aspect of the thorax alone, as is stated by some authors. The whole chest should be examined, particularly in doubtful cases. The signs of croupous pneumonia are most frequently discover- able at one or other base, posteriorly ; the friction sound of pleuritis at the junction of the middle and lower third of the chest, laterally ; and the signs of emphysema at the apices, anteriorly. Therefore, unless the exploration be thorough, important lesions may be overlooked. In healthy infants the inspiratory act in ordinary breath- ing is superficial, and the respiratory murmur, as a conse- quence, feeble. If, however, a deep inspiration be taken, a frequent occurrence under excitement and during crying, the murmur becomes loud, or assumes the character that Laennec termed puerile breathing. After the age of two years this form of respiration is habitual. Puerile breathing is characterized by its intensity, a prop- erty depending upon the thinness and elasticity of the chest- THE INVESTIGATION OF DISEASE. 5 I walls in childhood. There is no alteration in rhythm, the inspiratory element of the murmur being directly followed by the expiratory, and this in turn by an interval of silence ; neither is there any change in the pitch or duration of the expiratory sound, which remains lower and shorter than that of inspiration. In other words, puerile respiration is simply a very intense vesicular respiration. The normal respiratory murmur is then feebler in infants, and louder in children over two years old, than in adults. The breathing is loudest over the anterior, lateral and posterior inferior regions of the thorax. Faintest over the scapulae and the precordial area. Sometimes the expira- tory element is wanting. This absence occurs most fre- quently in young children, and is most noticeable over the lower posterior portions of the lungs. In the inter- scapular region, the ear, being directly over the larger bronchi, readily detects a deviation from the vesicular quality. Here the inspiratory murmur is loud, harsh and somew T hat tubular in character. There is a slight pause between it and the expiratory murmur, and the latter is longer in duration and higher in pitch. There is, in fact, an approach to the bronchial type of breathing, which may always be heard in its purity by listening over the trachea. Sometimes a difference in the breathing can be detected over the apices anteriorly. On the left side the vesicular quality is purer, on the right, the intensity is greater. The difference is most decided in the expiratory element, which, also, may be slightly prolonged on the right when com- pared with the left side. These modifications are due prin- cipally to the larger size and more horizontal course of the right primary bronchus. They are perfectly compatible with a normal state of the lungs. Should, however, the conditions at the apices be reversed, and the intensity and prolongation 52 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. of the expiratory sound be greater on the left side, the com- mencement of phthisis is indicated. If the child speaks, cries, or coughs while the ear is applied to the chest, a muffled rumbling sound, the normal vocal resonance, will be heard. At the same time, vibration of the walls, the vocal fremitus, can be felt. To develop the respiratory sounds it is often necessary to instruct the patient how to breathe, and if an infant is being examined, to take advantage of the deep inspirations that precede coughing, and occur during crying. The cardiac sounds are readily heard when the ear is placed on the praecordia. In young infants the examination is somewhat difficult, on account of the rapid and excitable action of the heart, but after the first year, the circulation becoming slower and more regular, there is little trouble in distinguishing the sounds, and even slight alterations pro- duced in them by disease. The first sound is longer and graver than the second, and the rhythm is ordinarily quite regular. In health the sounds may be heard under both clavicles for a short distance to the right of the sternum, and sometimes over the whole anterior surface of the chest. After muscular effort or during agitation, the heart sounds may be audible over the posterior aspect of the chest, but they are most distinct in this position when the lower lobe of either lung is consolidated by pneumonic exudation. The latter point is often of great value in distinguishing doubtful cases of pneumonia from pleural effusion. Palpation. — In practicing palpation the palmar surface of the well-warmed hand must be applied to the naked chest. This method of exploration is useful as a means of deter- mining the number of respiratory movements, the degree of expansion of the thoracic walls, the position of the cardiac apex beat, the presence or absence of painful regions and of THE INVESTIGATION OF DISEASE. 53 pleural or bronchial fremitus, the existence of fluctuation in the intercostal spaces, and the character of vocal fremitus. For the last purpose, though, it is hardly worth while to make a separate step in the examination, for the vocal vibra- tions can be readily distinguished by the ear when applied to the chest in auscultation. Percussion. — In percussing the different surfaces of the chest, the child must be placed in the same positions as for auscultation. When contrasting the two sides, percussion should be made in identical regions, and during the same period of the respiratory movement. Babies when con- strained or when disturbed, hold their breath in the intervals of crying, and as they always do so at the end of an in- spiration, this is a favorable time to seize for the compara- tive examination. The percussion strokes must be lighter than in the adult, but in other respects the operation in no wise differs. In health the resonance will be found to correspond closely with the respiratory murmur. Thus, in infants under the year, the respiratory murmur being feeble, per- cussion is rather insonorous. Even at this age the case is different, when a deep breath is taken, and so soon as puerile respiration becomes established the resonance is uniformly intense. With the exception of this greater intensity, the sound is exactly similar to that obtainable in adults. It is always attended, too, by a sensation of elasticity, appreciated by the finger used as the pleximeter. Different portions of the thorax possess, normally, differ- ent degrees of sonorousness. In front, the right side is markedly resonant from the clavicle down to the fifth interspace, or the upper border of the sixth rib in the mammary line, where the liver dulness begins. On the left side the resonance is equally intense, 54 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. but it is encroached upon by the gastric tympany, which extends upward as high as the seventh or sixth rib, as well as by the area of cardiac dulness. The latter forms an irregular triangle, of which one side is represented by a vertical line passing down the middle of the sternum, from the level of the fourth to the sixth rib ; the other, by an oblique line touching the upper extremity of the first, and extending outward to the left, and downward, to terminate at the point of the apex beat ; and the base, by a line drawn from the central point of the lower edge of the sternum (the inferior extremity of the first line), along the sixth costal cartilage, to the apex of the heart. Diminished reso- nance and elasticity are at once noticeable when the percus- sion passes from the lung to this area, though the precordial dulness is never so decidedly marked in children as it is in adults. Laterally, both supra-axillary regions are very resonant. The upper portions of the infra-axillary regions are a degree less resonant, and the lower portions are dull on account of the presence of the liver on the right and the spleen on the left side. The superior border of the liver dulness is found in the seventh interspace or at the eighth rib ; that of the spleen, at the upper edge of the ninth rib. Gastric tympany may supplant the pulmonary resonance over the left infra-axillary region. Posteriorly, there is little resonance in the scapular region, particularly the supra-spinous portions. Over the inter- scapular space the sound improves, but it is less resonant than anteriorly or laterally. Over the infra-scapular regions the resonance is but little less pure than in front, until the tenth rib is reached on the right side and the liver dulness is again met with. On the left side the resonance ex- tends to the very base, the posterior splenic dulness being THE INVESTIGATION OF DISEASE. 55 detected with difficulty. The right base is, therefore, naturally less resonant than the left, and this difference is especially marked during expiration, the liver rising higher at that time. Affections of the lungs produce various alterations in the percussion sound. The chief of these are the substitution of tympany, of dulness, and of flatness for the normal resonance, and of increased resistance to the finger for elasticity. Cardiac diseases cause changes in both the extent and the shape of the area of precordial dulness. Examination of the Mouth and Fauces. — This portion of the examination is most apt to cause crying and strug- gling, but it must never be omitted. In infants, gentle pressure of the fingers upon the chin is sufficient to cause wide opening of the mouth. An older child will fre- quently open the mouth when requested, but if he refuse, the finger, the handle of a spoon, or some other smooth, flat instrument may be inserted in the mouth, and downward pressure made upon the tongue, when the jaws will be widely separated. In some cases, when the child is old enough to do as bid, the fauces can be seen by directing the mouth to be opened wide and the tongue to be alternately protruded and retracted, or a prolonged sound of "Ah " to be made. With the refractory, and always with infants, the tongue has to be held down by a spoon handle or tongue depressor. If there be resistance, the patient must be taken on the lap of the nurse, who holds his back against her breast, directs his face toward a bright light, and controls the movements of his hands and feet. The healthy oral mucous membrane has a deep pink color, and is smooth, moist and warm to the touch. The color is deeper on the lips and cheeks, lighter on the gums. The latter, up to the sixth month, as a rule, have a moder- $6 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. ately sharp edge. Subsequently, the edge begins to broaden and soften, and the color of the investing mucous mem- brane deepens to a vivid red, and becomes hot, as the teeth begin to force their way through. The first, or milk teeth, so called from their color, are twenty in number, all told, ten to each jaw ; they make their appearance in the follow- ing order, the corresponding teeth appearing a little earlier in the upper jaw* : — The two lower central incisors, from 4 to 7 months after birth. " four upper •' " 8 to 10 " " " " two lower lateral incisors and the four anterior molars, from 12 to 15 " " " " four canines, " 18 to 24 " " " " " posterior molars, " 20 to 30 " " " The order of eruption of the permanent teeth is as fol- lows : — The two central incisors of lower jaw, from the 6th to 8th year. " " " upper four lateral " " first bicuspids, " canines, " second bicuspids, 7th to 8th 8th to 9th 9th to 10th 10th to nth 1 2th to 13th These replace the temporary teeth ; those which are developed de novo appear thus : — The four first molars, from the 6th to 7th year. " " second " " " 12th to 13th " " " third " " " 17th to 2 1st " There are, therefore, twelve more permanent teeth, mak- ing thirty-two in all, sixteen in each jaw. The tongue should be freely movable. It is pink in color, and the dorsum, or upper surface, marked in the centre by a * Upon this point, however, there is little uniformity. THE INVESTIGATION OF DISEASE. 57 slight longitudinal depression, has a velvety appearance, and is soft, moist, and warm to the finger. The velvety nap is due to the numberless hair-like processes of the filiform papillae. There are also scattered over the surface, but most closely at the tip, a number of eminences, the size of a small pin's head, circular in outline, and deeper pink than the general surface — the fungiform papillae. While far back, defining the papillary layer, are the circumvallate papillae, numbering about twelve, and arranged in a V-shaped row. These have the form of an inverted cone, surrounded by an annular elevation. The hard palate is roughened anteriorly by transverse ridges. The soft palate is smooth and its mucous membrane is paler than that of the rest of the mouth. The fauces, on the contrary, are redder. In the triangular recess between the half arches of the palate the tonsils can always be seen. They should be about the size and shape of almond kernels, and they present a number of circular openings, the orifices of pouches, into which the follicles open. The uvula is short and tongue-shaped. The posterior wall of the pharynx should be red, smooth and moist. Disease produces a great variety of changes in the mouth, tongue and fauces. Fever makes the mouth hot and dry, and causes the tongue to be frosted or coated. Affections of the gastro-intestinal tract are always attended by coating of the tongue, and the various appearances of this coating are of important diagnostic and therapeutic significance. In- flammation of the mouth itself, reddens the mucous mem- brane, makes it hot and tender to the touch, increases its moisture, alters the surface of the tongue and leads to the formation of aphthae, to ulceration, and even to gan- grene. The eruptions of scarlet fever, measles, varicella and vari- 58 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. oloid make their appearance first on the mucous membrane of the palate and fauces. Irregular dentition indicates faulty nutrition ; delayed dentition, rickets ; and certain peculiarities in the formation of the permanent teeth, constitutional syphilis. Finally, the conclusive evidences of the existence of diph- theria, of croup, and of the various tonsillar affections, are found in the fauces. PART II.— DISEASES OF THE DIGESTIVE ORGANS. CHAPTER I. AFFECTIONS OF THE MOUTH AND THROAT. i. CATARRHAL STOMATITIS. The Anatomical Lesion in this affection consists of a simple hypersemia of the mucous membrane of the mouth, with its attendant redness, swelling, and altered secretion. This hypersemia varies both in extent and degree. Some- times it is limited to small, circumscribed points of the membrane, at others it extends over large patches, or in- volves the entire surface. In the latter cases, it is most in- tense, the mucous glands of the lips and cheeks participate, becoming enlarged and prominent, and occasionally small herpetic patches appear. The disease may be primary or secondary. Etiology. — The causes of primary stomatitis are the in- gestion of food or drinks which are acrid and irritating or too hot ; the eruption of teeth ; the presence of decaying teeth; want of cleanliness of the mouth; exposure to cold and wet ; and the use of certain drugs, as mercury, iodine, antimony and arsenic. The secondary form occurs during the course of measles, scarlatina, typhoid fever, and disor- dered conditions of the stomach, particularly those attended 59 60 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. by acid eructations. Catarrhal stomatitis is also met with in the earlier stages of more serious diseases of the mouth. While not limited to any special age, the disease occurs most commonly during dentition, since at this period several of its causes are apt to be simultaneously operative. Symptoms. — These are mainly local. The lips are unnatu- rally full and red, and the skin at the angles of the mouth and on the chin may be excoriated by the dribbling saliva. The oral mucous membrane presents either a punctated, a patchy, or a diffuse redness. It is moderately swollen, and hot and tender to the touch. At first the mouth is dry, but soon the salivary flow is increased, the secretion becoming acid in reaction, and sometimes viscid and flocculent. The mucous glands of the cheeks and lips may project as yel- lowish-white or transparent nodules, yielding a drop of mu- cus on pressure. Infrequently, too, isolated collections of small vesicles develop and then quickly dry up, leaving scales behind them. The tongue is either red and smooth, with enlarged and reddened fungiform papillae, or covered with a white frosting, through which the papillae project in scarlet points. The last condition is most frequently seen when the stomatitis is secondary to gastric catarrh. The acts of sucking and eating are painful, and resistance is offered to inspection of the mouth. Cold drinks are craved. Restlessness, irritability, slight heat of skin, anorexia — depending chiefly upon the local tenderness — and constipa- tion, are the general symptoms of primary catarrhal stoma- titis. In the secondary variety the general symptoms depend upon, and vary with, the originating disease ; the local features, however, remain the same. The course of the disease depends upon the cause, and AFFECTIONS OF THE MOUTH AND THROAT. 6 1 the treatment adopted, though it is usually acute, rarely lasting longer than a week. Treatment. — After attending to the removal of the ex- citing cause, if this be possible, the diet must be regulated. To sucklings, the breast or the carefully prepared bottle, alone should be allowed, and milk guarded by lime-water must constitute the food of older children. If the act of sucking be so painful as to cause the infant to refuse the breast or bottle, it is necessary to give food, temporarily, from a spoon or glass. The mouth should be thoroughly washed, at intervals of an hour while the patient is awake, with a solution of borax or chlorate of potassium in rose water (gr. x to foj). After taking food, particularly, the mouth ought to be cleansed with cool water, and the lotion used. A little mass of absorbent cotton twisted around the end of a probe, or a soft rag folded around the index finger, are the best vehicles for carrying the lotion. Regular evacuation of the bowels must be secured by saline laxatives. If the skin be hot and dry, liquor potassii citratis, in doses of a fluidrachm every two or three hours, for a child of a year old, is indicated. When the tongue is heavily frosted, and the stomach disordered, recovery may be much hastened by using the following prescrip- tion : — ]J . Sodii Bicarbonatis, gr.xxiv. Pulv. Pepsinse, gr.xij. Pulv. Aromatici, gr.iij. M. et ft. chart. No. xij. S. — One powder four times daily, administered in milk or syrup, for a child between seven and twelve months old. 62 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. 2. APHTHOUS STOMATITIS. This is a much more common disease than uncompli- cated catarrhal stomatitis, and is most frequently met with in children between the ages of six and fifteen months. The Anatomical Lesions are hyperemia of the mucous membrane of the mouth, and the formation of aphtha or small, superficial, yellowish-white ulcers. Etiology. — Any condition which reduces the general strength and interferes with nutrition may exert a predis- posing influence. For instance, over-crowding ; residence in damp, ill-ventilated houses or rooms ; insufficient food and clothing ; chronic diseases, especially of the digestive tract ; scrofula and the tuberculous tendency. The exciting agencies are, want of proper attention to the cleanliness of the mouth ; foul nursing bottles ; the admin- istration of sour milk, or an excess of farinaceous food, and dentition. After the completion of the first dentition, an indulgence in pastry or candy is often followed by an attack of aphthae, and certain children always suffer after eating some particular article of food, as honey, walnuts, or salted fish. All of these causes are active in the production of a catarrhal state of the stomach, which invariably precedes and attends the disease under consideration. The disease is not contagious, though at times a sufficient number of cases occur simultaneously to constitute an epidemic. Symptoms. — For twenty-four hours prior to the ap- pearance of aphthae, there is fretfulness, increased thirst and poor appetite, Next, the mouth becomes hot, and a few hours later the ulcers appear, without any previous vesication.* The lips, swollen and vividly red, are held * For confirmation of this statement, see Vogel, Ziemssen's Cyclopaedia, Vol. vi, p. 779. AFFECTIONS OF THE MOUTH AND THROAT. 6$ somewhat apart, and clear saliva drops from the mouth, excoriating the skin of the lower lip and chin. The oral mucous membrane is red, swollen, and hot, and presents the characteristic ulcers. These are usually discrete, and make their appearance first on the inside of the lower lip and the edges of the tongue, though they may, subsequently, ex- tend to the cheeks, gums, soft palate, and even the tonsils. Their number varies from one to twenty, and their size, from that of a pin's point to a split pea. The ulcers, oval, round, or, more rarely, linear in shape, are slightly elevated above the surrounding surface, have deeply reddened edges, and whitish or yellowish-white floors. They are exces- sively sensitive, and thus mechanically interfere with sucking, chewing, speaking, or other movement of the mouth. The edges of the tongue are clean and red, while its dorsum is covered with a thick, white coating. Together with these local symptoms, there is restlessness, increased pulse rate, elevated surface temperature, dryness of the skin, thirst, anorexia, nausea with frequent eructa- tions of acid liquid and occasional vomiting, and either con- stipation or diarrhoea. The loss of appetite is due both to the painful condition of the mouth and to the disordered state of the stomach. When all the ulcers appear simultaneously, the disease runs its course in from four to seven days. The fibro- cellular exudation covering their floors then disappears, leaving the mucous membrane beneath intact but intensely red, though occasionally shallow, clean ulcers are left, which quickly heal. At the same time the local and constitu- tional symptoms rapidly subside. If, on the contrary, the ulcers develop in successive crops, as is sometimes the case, the duration may be prolonged for a fortnight or more. There is another form of aphthous stomatitis, termed 64 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. confluent, in which the aphthae are very numerous, and tend to run together, forming large irregular ulcers. The symp- toms are proportionately severe. It occurs secondarily to grave constitutional diseases — namely, measles, variola, scarlet fever, diphtheria, typhoid fever, pneumonia and whooping cough. The Diagnosis of the ordinary, discrete form is unat- tended with difficulty. Thrush bears the closest superficial resemblance ; but in this disease the creamy-white spots are slightly raised above the surface, being deposits upon the mucous membrane. There are no ulcerations, the color of the free membrane is rather purplish than scarlet, and finally the thrush fungus is discoverable by the microscope. The graver, confluent form is distinguished from ulcerative stomatitis, by the absence of fetor, and by the different seat and appearance of the lesions. The ulcers in the latter dis- ease always beginning at the margins of the gums, extend rapidly, and present grayish floors. Aphthse is usually a mild disorder, recovery taking place quickly and without difficulty. The confluent form, besides running a longer course, is more difficult to cure, on account of the general debility induced by the associated disease. Treatment. — Since some disturbance of digestion is con- stantly at the bottom of the local trouble, attention to the feeding apparatus and to the diet is of great importance. Absolute cleanliness of both bottles and tips must be insisted upon, and if a complicated, patent arrangement of rubber and glass tubing has been used with the bottle, it must be at once discarded and a simple rubber tip substituted. Regular hours for meals — the frequency varying with the aere of the child — are as essential as the selection of suitable food, and its administration in proper quantities. A child of six months should be fed every three hours, AFFECTIONS OF THE MOUTH AND THROAT. 65 between 6 o'clock in the morning and 9 o'clock in the even- ing. A mixture such as the following — Sound milk, f^iv- Cream, f^j. Lime-water, f^ij- Sugar of milk, ..... . one teaspoonful (gr. xl); may be made immediately before the time of feeding ; poured into an absolutely clean bottle, to which a clean tip is fitted, and the whole placed in a water-bath and heated to a temperature of about ioo° F. This preparation is easily digested, contains enough lime-water to prevent rapid and firm clotting o'f the milk, and is not so great in quan- tity as to over-distend the delicate stomach and cause vomiting. Children of two years of age and over should be placed on a simple diet. A breakfast, luncheon and supper of stale bread and milk guarded by lime-water (one part to three) and a mid-day dinner of broth and well-boiled rice. The disease usually makes its appearance too long after the causative error of diet, to be stayed by the administration of an emetic. If, however, an overloaded stomach be indi- cated by fever, restlessness, and epigastric pain and disten- sion, a dose of the wine or syrup of ipecacuanha* should be given. If the bowels be constipated a gentle laxative is required. Probably the best is calomel ; for a child from six to twelve months old a powder containing half a grain of the mercurial and five grains of sugar may be placed dry upon the tongue in the evening, to be followed next morn- ing by a small teaspoonful of magnesia in milk or lemon- ade. If, on the contrary, there be diarrhoea, the bowels should be first cleared of irritating materials by a teaspoon- * For a child of one year old the emetic dose of wine of ipecacuanha is fifteen drops, of the syrup half a teaspoonful, repeated if necessary. 5 66 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. ful of castor oil, into which five drops of paregoric have been dropped, and the following prescription given : — R . Sodii Bicarbonatis, gr.xxiv. Syr. Rhei Aromatici, Syrupi, aa f^ss. Aq. Menthse Piperita? q. s. ad f^iij. M. S. — A teaspoonful every three hours. The fever, when very moderate in degree, requires only a plentiful supply of cool water to drink, and a hot mustard bath in the evening. The strength of the latter should be one teaspoonful of strong mustard to as much water as will cover the child's legs and hips when in a sitting posture. The duration of the bath should be from five to ten minutes. If the skin be quite hot and dry, a saline diaphoretic is necessary. The best is liquor potassii ci- tratis, in doses of one teaspoonful every two hours. Some- times it is well to add one-quarter of a drop of tincture of aconite to each dose of the potash solution. Locally, the best results will be obtained by lightly touching each ulcer with a point of lunar caustic. This causes considerable suffering at the moment of application, but is followed by lessening of the pain and rapid healing. In ordinary cases one such application suffices, in severe, it is necessary to repeat it daily for a week or more. In addi- tion the mouth must be washed thoroughly and frequently, particularly after food is taken, with cool water, or with a solution of chlorate of potassium, as: — &. Potassii Chioratis, gr. xx. Vini Opii, TT\v. Glycerinae, f^j. Aquas Rosas, q. s. ad f^j. M. After the fever has subsided, a digestant will be required AFFECTIONS OF THE MOUTH AND THROAT. 6j for a few days. Thus, half a teaspoonful of wine of pepsin three times daily may be ordered ; or, if there be acidity with a coated tongue, the powder recommended, under the same circumstances, in catarrhal stomatitis. The local treatment must be persevered in, until the ulcers have healed and the mucous membrane has returned to its normal condition. 3. ULCERATIVE STOMATITIS. This affection of the mouth is quite common in child- hood. It is usually seen in children between three and eight years of age ; is never met with before the commencement of dentition, and is not contagious, though it sometimes occurs in almost epidemic profusion. The Anatomical Lesions consist of parenchymatous inflammation of the gums, and often of the tongue and cheeks, with ulcerative destruction of the mucous mem- brane. Microscopical examination of the floors of the ulcers, reveals pus corpuscles, isolated blood corpuscles, and granulated cells, imbedded in an amorphous, finely granular mass which is filled with bacteria and micrococci. There is no trace of pseudo-membrane. Etiology. — As the disease is not contagious there is prob- ably no specific epidemic influence in its causation. When groups of cases, large enough to be classified as epidemics, do occur, they are generally limited to single houses or institutions, and may be traced to bad hygienic surround- ings affecting alike all the inmates. Insufficient or bad food and residence in unhealthy, cold, damp, ill-ventilated houses constitute one set of causes. Again, ulcerative stomatitis is very apt to follow in the 68 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. wake of typhoid fever, scarlatina, measles, variola and dys- entery, and since each of these primary diseases usually occurs as an epidemic, a similar tendency in the sequel is readily explained. A certain amount of reduction of the constitutional vigor seems to be an essential precedent to the development of the disease. Sickly, rickety and scrofulous children are susceptible subjects, and when the gums are loose, soft and hypersemic they are more readily affected than when firm and closely applied around the teeth. The presence of decaying teeth, want of cleanliness of the mouth, and the careless administration of such medicines as mercury, lead and phosphorus, are exciting causes. Symptoms. — At first there is a sense of heat and pain in the mouth, and the breath grows offensive in odor. Next the gingival mucous membrane, immediately about and be- tween the teeth, becomes red and swollen. The swelling rapidly increases, the points of the gum between the teeth standing out like flasks, and the whole margin becoming so soft and tender that it bleeds upon the lightest touch. In the course of twenty-four hours the edge of the gum, where it touches the teeth, changes from a bright red to a yel- low or yellowish-gray color, and softens, breaking down into ulcers. Ulceration generally commences on the external surface of the lower gum, and in the beginning appears as a more or less extended, narrow and indented gray band, follow- ing the line of the teeth. Later it may appear on the outer surface of the upper gum ; on the internal surface of both the lower and upper gums ; on the edges of the tongue, at points where the organ presses against the teeth ; and finally on the cheeks. In the latter position it often hap- pens that the ulceration corresponds exactly with that of AFFECTIONS OF THE MOUTH AND THROAT. 69 one or both gingival borders, forming a single or double strip running parallel with the jaws. The ulcers are depressed, have a ragged, dirty gray or brownish floor, and intensely red, swollen edges. The un- involved mucous membrane shows the characters of catar- rhal stomatitis. When the disease is fully developed, the lips are tumid and red. They are held apart, and a stream of yellowish, sometimes bloody, always ill-smelling, acid and viscid saliva, constantly drips away, excoriating the skin over which it flows. If the mouth be kept closed, as it sometimes is, half an ounce or more of this fetid fluid gushes out whenever the lips are parted in speaking or in taking food. The sub- maxillary glands and the lymph glands of the neck are moderately enlarged, and there is often oedema of the face, limited or general, according to the extent of the ulceration. The mouth is the seat of constant burning and pain ; is hot and tender to the touch, and chewing causes great suf- fering. Between and upon the teeth there is a deposit of yel- low unctuous material. The tongue, in addition to present- ing the marginal ulcers, is swollen and heavily coated with a dirty, yellowish-white fur. The speech is thick ; the breath has a characteristic heavy odor; there is loss of appetite, due principally to the pain produced by chewing and the contact of food with the ulcerated mucous membrane ; thirst is mode- rately increased ; and the bowels are normal, or inclined to constipation. The little sufferer is restless and sleeps badly. The pulse is feeble, and there are other evidences of general debility, but there is little febrile reaction, the temperature even in well marked cases, rarely reaching a higher marking than 99.5 ° F. in the evening. In severe and protracted attacks, the ulcers increase in breadth and depth, become covered with a gray or brownish JO DISEASES OF DIGESTIVE ORGANS IN CHILDREN. pulp, and the teeth, deprived of the support of the gum, grow loose and are easily removed from the alveoli. Some- times the periosteum of the jaw is destroyed, and more or less extensive necrosis results. Exceptionally, in very weak and badly nourished children, the stomatitis runs into actual gangrene or noma. The symptoms, ordinarily, reach their height in from two to four days, and, under proper treatment, disappear in as many more, the ulcers cleaning off and healing without cicatrization. Severe, or badly managed cases go from bad to worse for a time, and rarely recover under three or four weeks, during which the suffering is extreme. Those in- volving necrosis of the jaw, and those terminating in noma, run a still more protracted course. Diagnosis. — The appearances of the gums before ulcera- tion, the position in which this process begins, the character of the individual ulcers, and the odor of the breath, furnish a train of symptoms distinguishing ulcerative stomatitis from any other affection of the mouth. The Prognosis, in the vast majority of instances, is most favorable. When necrosis of the jaw occurs the duration is greatly prolonged, but ultimate recovery is the rule. In- tercurrent noma, on the contrary, often leads to the death of the child, and under the best of circumstances leaves its traces in permanent deformity of the face. Treatment. — The first step is to improve the sanitary surroundings of the patient, or, if this be impossible, to remove him to healthy quarters. The importance of clean- liness, fresh air, and sunlight, are not to be lightly estimated. The diet should be liquid, but nutritious. Apart from the fact that solid food will be refused on account of the pain entailed in its mastication, milk and animal broths are better suited to the somewhat enfeebled digestive powers, and AFFECTIONS OF THE MOUTH AND THROAT. J\ should be relied upon entirely. Cool water ought to be allowed in sufficient quantities to satisfy the thirst. Of drugs, chlorate of potassium is the most important, since it ranks almost as a specific for this disease. It may be given alone, simply dissolved in water, or combined with dilute muriatic acid, as in this prescription : — R. Potassii Chloratis, . • gr.xlviij. Acidi Muiiatici dil., f,5J. Syrupi, fj> ss « Aquas, q. s. adf^iij. M. S. — One teaspoonful, diluted, every two hours, for a child three years old. In this combination, the chlorate of potassium being eliminated by the salivary glands, constantly comes in con- tact with, and acts as an alterative upon, the ulcers. The muriatic acid aids digestion, and acts as a tonic. If a more decided tonic effect be required, one-quarter to one- half of a grain of sulphate of quinia may be added to each dose. Chlorate of potassium, too, constitutes the main element of the local treatment. Its action is somewhat improved by the addition of carbolic acid, as in the following wash : — R . Potassii Chloratis, gr.lxxx. Acidi Carbolici, g r -i> Glycerinee., f^j. Aqua?, q. s. adf^viij. M. A bit of absorbent cotton saturated with this wash should be thoroughly applied to all the ulcers at least once in every hour ; or, at the same intervals, the child may take a quantity into the mouth, move the cheeks and tongue in such a way as to bring it in contact with the whole mucous surface, and then expel it. J2 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. After the ulcers have healed, the specific treatment may be discontinued, and the patient placed upon a simple tonic, as ferrated elixir of cinchona, in doses of half a flui- drachm three times daily, until the health is perfectly restored. As additions to this treatment, iron and stimulants will be required in severe and protracted cases. The tincture of the chloride is the best form of iron. It should be given in doses of three drops (n\,iss) every two hours for a child three years old, and may be combined very well with the mixture of potash, acid and quinine. The best stimulant is whiskey, in doses of one-half to one teaspoonful, in milk or water, every three or four hours. Indolent ulcers may be stimulated to heal by touching them lightly with a solid stick of nitrate of silver. Loosened teeth must always be allowed to remain in position, as they often become firm again after the termination of the disease. When necrosis occurs, no change is necessary in the general plan of treatment. Especial attention, however, must be paid to the cleanliness of the mouth, and poultices of flaxseed meal should be kept constantly applied to the cheek of the affected side. Surgical interference may become necessary. 4. GANGRENOUS STOMATITIS— NOMA. This affection consists of a rapid gangrenous destruction of the cheek and adjacent parts, occasionally beginning on the lips, but usually near one corner of the mouth. It is generally asymmetrical, the left cheek being attacked in the majority of instances, but sometimes both cheeks are sim- ultaneously involved. AFFECTIONS OF THE MOUTH AND THROAT. 73 Etiology. — Noma is, fortunately, an uncommon disease. Sucklings seem to be exempt from it, and most of the cases occur between the ages of two and twelve years. Girls are more liable to be attacked than boys. It is always of secondary origin, following severe maladies, such as measles, typhoid fever, gastro-intestinal catarrh, ulcerative stomatitis, scarlet fever, smallpox, broncho-pneumonia, tuberculosis, protracted intermittent fever and whooping cough. This order also represents the etiological activity of the diseases mentioned. These, then, may be looked upon as predis- posing causes, but despite the presence of any one of them, noma only occurs in those children who have been pre- viously weak, ill-housed and ill-nourished. There is no evidence to show that it is contagious, though it sometimes occurs as an endemic in overcrowded hospital wards and children's homes. These endemics may be ex- plained in the same way as similar outbreaks of ulcerative stomatitis. Symptoms. — During convalescence from measles, or other of the diseases mentioned, a nodule, from a quarter to half an inch in diameter, appears spontaneously upon the child's cheek, in the neighborhood of the corner of the mouth. This can be easily detected from the outside, but it is best felt by opening the mouth and grasping the cheek between the thumb and forefinger. It is extremely hard, and very sensitive, especially at the periphery. If the case be seen during the first few hours, the mucous membrane over the mass will be observed to be converted into a flat, ichorous bulla. Usually, however, this membrane is found hanging in ragged shreds from a black, gangrenous base. The skin over the induration is pale or mottled with purple spots, tense, and shiny as if oiled. After twenty-four hours, the investing integument becomes 74 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. bluish, the epidermis scales off, and a black eschar forms. This has a tendency to shrink, and in so doing, leaves a linear depression filled with ichor, which separates it from the healthy skin. Notwithstanding this line of demarcation, the tissue destruction rapidly extends, both in superficial area and depth. Soon the cheek is perforated, and a dirty, stinking, ichorous saliva, filled with shreds of broken- down tissue, flows out beside the eschar and over the cheek. At the same time the lips, chin, and uninvolved portions of the cheek become cedematous, the skin being tight and glistening, and the adjacent cervical glands en- larged. At the very outset there are few constitutional symptoms. The child complains of little or no pain, persists in his amusements, has a good appetite, a temperature but slightly above the normal, and a pulse but moderately increased in frequency. As the eschar forms, the scene changes, symp- toms of constitutional depression setting in. The face is pale and expressionless on the affected side, the skin cool and dry, the pulse feeble and frequent — sometimes counting 1 20 or 140 beats per minute — and there is oedema of the feet. The mind is apathetic, no complaints of pain are made, and at most a sense of discomfort is indicated by con- stant whimpering. The mouth is held partly open, the breath is fetid, the teeth and tongue are covered with sordes, and there is an abundant flow of bloody or dark- colored saliva. Severe hemorrhage never occurs, as the blood vessels are closed at an early stage. The appetite is often retained, the thirst is intense, and the bowels are usu- ally relaxed. In spite of the food taken, the strength rapidly declines, sometimes, though, it is wonderfully re- tained, the patient being able to sit up, and even leave his bed, until a few hours prior to death. AFFECTIONS OF THE MOUTH AND THROAT. 75 The air of the sick-room has a characteristic gangrenous odor. Perforation of the cheek occurs about the third day of the disease, and many cases die at this time. Others linger until the end of the first or second week. Under these cir- cumstances the gangrene invades the lips as far as the median line, the corresponding ala of the nose, and the cheek as far as the lower eyelids, the tragus, and the infe- rior border of the lower jaw. Extending inward, the gums and periosteum of the jaws are destroyed ; the bone becomes necrotic, and the teeth so loose that they can be readily pushed out by the finger, together with pieces of the alveoli. Finally the cheek is cast off in large, black sloughs, leaving huge openings, with black, ragged, and indurated edges, through which the blackened and necrosed bones and loosened teeth can be seen. The child's face is then unrecognizable ; the symptoms of constitutional depression are greatly intensified ; there is delirium, profuse diarrhoea, purulent and even gangrenous infiltration of the lungs, and occasionally, also, gangrene of the genitalia, in females. Death is the only result to be expected. Exceptional cases do recover. In these, the gangrenous edges become clean and covered with granulations, the necrosed bone is thrown off, and after months, cicatrization takes place, with great disfigurement. Pathology and Morbid Anatomy. — The fact that noma makes its appearance uniformly at one point, on the cheek, and is unilateral, suggests a localized, causative lesion. The most natural theory, that of embolism of a large arte- rial branch, due to weakness of the cardiac muscle or in- creased coagulability of the blood — effects of the primary disease — is untenable, because, with the given conditions, emboli ought, at least occasionally, to be found in other y6 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. positions, which does not happen. It is necessary to look rather to the nerves ; namely, the trifacial, the facial, or the vaso-motors. That the gangrene is due to a lesion of one of these, seems to be borne out by experiments. Thus, Magendie found that division of the trifacial in dogs caused destruction of the corresponding eyeball, and half of the tongue became dry, brown and fissured, the gums spongy and hemorrhagic, and the teeth loose. " In animals tena- cious of life, the batrachians, for example, the soft portions of the face are cast off in shreds, just as in spontaneous gangrene. After three or four weeks only one-half of the face remains." * The body of a child dead from noma has a gangrenous odor and decomposes quickly; the skin is shriveled, and the face and the feet are cedematous. The gangrenous parts are converted into a blackish-brown mass, and the maxil- lary bones are naked, brownish in color and brittle. The nerves, when examined microscopically, are yellowish in color but unaltered in structure, and the blood vessels are thickened and filled with thrombi. In the uninvolved parts of the cheek there is a dense exudation, while the palate, tongue and tonsils are swollen and covered with black scales and crusts. The lungs are the seat of hemorrhagic infarc- tions, lobular or metastatic lobar pneumonia, and sometimes gangrene. The intestines are catarrhal. Evidences of the primary disease may also be present; for example, the lesions of typhoid fever or dysentery. Diagnosis. — Noma is readily distinguished from other oral affections by its course, its peculiar and almost uni- formly identical seat and its well marked local features. Ulcerative stomatitis is the only other of the class at all likely to be confounded with it. This always begins with * Vogel, Ziemssen's Cyclopaedia, Vol. vi, p. 812. AFFECTIONS OF THE MOUTH AND THROAT. JJ ulceration of the gingival margin, and when the cheek becomes involved, the ulcers situated there are linear in shape and have a grayish floor. There is no sloughing or gangrene of the mucous membrane. The cheek never presents a circumscribed induration, being at most simply cedematous. The skin shows no tension, unctuous appear- ance or discoloration, and perforation of the soft parts never occurs. The breath is fetid but not gangrenous ; salivation is less, and the saliva, though sometimes bloody, is not mixed with shreds of gangrenous tissue. The course is much less rapid, and the ulcers, while they extend in area, retain the same appearances throughout. Finally, the general symp- toms are distinctive, the results of treatment are most satis- factory, and a fatal termination is extremely uncommon. Malignant pustule closely resembles noma. The former, however, always begins on the exterior, involving the epi- dermis first and extending through the successive layers of skin to the deep structures. The Prognosis is most unfavorable. Vogel sets the mortality at 80 to 90 per cent,* and out of one hundred and two cases that came under the observation of Steiner,f only four recovered. Death may occur at any time between the third and fourteenth day; a rapid course, however, is very much more frequent than the reverse. Even when recovery does take place, the patient is permanently disfigured by scars, or crippled by the development of ectropion, or of re- stricted movement of the jaw, in consequence of cicatricial contraction, or by the loss of teeth and portions of the max- illary bones. Such cases also drag through a very pro- tracted convalescence. Treatment is most unsatisfactory. Something can be * Ziemssen's Cyclopaedia, Vol. vi, p. 814. I Diseases of Children, p. 218. yS DISEASES OF DIGESTIVE ORGANS IN CHILDREN. done in the way of prophylaxis, by a proper management of the known predisposing diseases. Secure sound hygiene in the sick-room ; give good nourishment, and avoid the abuse of mercurials and debilitating treatment generally. If, notwithstanding these precautions, noma appears, it is of the first consequence to maintain the strength by the use of concentrated liquid food, tonics and stimulants. When perforation of the cheek takes place, the act of swallowing is mechanically interfered with. It is necessary then to resort to nutritious enemata, suppositories of quinia, and even the rectal administration of stimulants. The room in which the treatment is conducted must be large, airy, and so situated as to be exposed, for a part of the day, at least, to the sun's rays. In summer the win- dows should be kept constantly open, and in winter they must be raised for at least fifteen minutes several times daily, the patient being warmly covered in the meantime. The air of the chamber must also be kept as pure as pos- sible by the use of disinfectants. For this purpose cloths saturated with a solution of chlorinated soda or with Piatt's Chlorides, may be hung about the bed. Early cauterization with the hot iron, with strong sul- phuric or muriatic acid, or the solid stick of nitrate of silver, is recommended. All sloughs must be removed by scissors. The gangrenous spot should be frequently bathed with a strong solution of chlorate or permanganate of potassium, carbolic acid, or chlorinated lime. Pieces of lint soaked in one- of these solutions, may, with advantage, be left in con- tact with the ulcer, if the child will tolerate a fixed dressing. In case of perforation, much of the wash will run into the mouth, and care must be taken to prevent its being swal- lowed. The mouth must be kept as clean as possible by repeated syringings with a solution of chlorate of potassium AFFECTIONS OF THE MOUTH AND THROAT. 79 and carbolic acid, ten grains of the former and one grain of the latter to the fluidounce. When recovery occurs, loss of tissue, and the deformities resulting from cicatricial contraction, may be, to some ex- tent, remedied by plastic surgery. 5. PARASITIC STOMATITIS— THRUSH. Thrush is characterized by the appearance of numerous, rapidly-growing, white, curd-like flakes upon the oral mu- cous membrane ; the latter being in a more or less catarrhal condition, injected, swollen, hot and tender to the touch. The flakes are due to the development of a peculiar vege- table parasite, the O'idium Albicans. Thrush occurs both as a primary and a secondary affection. Etiology. — The disease attacks sucklings, and is met with most frequently during the first three months of life. Children nursed at a healthy breast are never attacked, and rarely those belonging to the well-to-do classes, because of the attention given to cleanliness of the mouth and feeding apparatus. Neglect of this fundamental principle, cleanliness, lies at the foundation of every case of primary thrush. Foulness of the mouth implies a condition in which the secretions and the food clinging to the mucous membrane are under- going acid fermentation, a necessary precedent to the de- velopment of the fungus. Given this condition, thrush originates by contact with other cases, through the media of bottle tips, spoons, tumblers, or cups used in common, and is produced, de novo, by carelessly kept tips and bottles, and, more frequently still, by long nursing tubes which are always partially clogged, acid and ill smelling. 80 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. The secondary form has the same direct causes, but arises during the course of gastro-intestinal disorders, especially those resulting from a too free dietary or the over-use of farinaceous food. It may occur, also, as a complication of diseases that greatly impair the general nutrition, as the exanthemata, tuberculosis, scrofula, spinal caries, etc. The disease is most prevalent during the summer months. The Morbid Appearances are the same in both forms. Prior to the appearance of the flakes, the oral mucous membrane is purplish-red and sticky, and its secretion is acid in reaction. The latter shows, under the microscope, numerous spores, egg-shaped, sharply-outlined, and hanging together in twos and threes. Soon, isolated white points, as large as a pin's head, appear on the inside of the cheeks. These rapidly increase in extent and number; involve other parts of the mucous membrane, and often as early as the second or third day, large, white flakes are formed. Later still, the whole cavity of the mouth; and, in some cases, even the pharynx and oesophagus are covered. The patches, at first white, may become yellow, and some- times brown, if bleeding occur from rough handling of the mucous membrane. Their surface is somewhat velvety, and they are soft, breaking down like curd under the finger. During the first few days they adhere firmly to the mucous membrane ; afterwards they become quite loose, and can be wiped off readily, leaving the epithelial surface intact. Microscopic examination of the fully formed patches reveals numerous irregularly developed fungoid fibres, with laterally branching arms and buds, interspersed with round or oval sporules, and imbedded in an amorphous, granular mass. A hardened section of a patch and mucous mem- brane to which it adheres, shows, in addition to these char- acters, a partial loss of epithelium, and a tendency on the AFFECTIONS OF THE MOUTH AND THROAT. 8 1 part of the filaments to penetrate into the mucous glands and between the cells to the deeper layers of the epithelium. The fungus seems to grow only upon squamous epithe- lium, so that it is never found in the nasal cavities, the la- rynx or the trachea, and the presence of loose masses of it in the stomach may be regarded as accidental. On the other hand it may be formed upon the lower segment of the rec- tum, the female genitals, and on abraded surfaces about the mouth, chin and neck. Symptoms. — The primary form begins with heat, dryness, tenderness, slight swelling and uniform redness of the mucous membrane of the mouth. The redness is combined with a purple tinge which is most marked on the dorsum of the tongue. Here, too, prominence of the fungiform pa- pillae is noticeable. The child takes his food moderately well, but the meals are frequently interrupted on account of the pain caused by sucking. He is fretful and sleeps poorly. The bowels are moderately relaxed, the stools being liquid and yellow in color. In the course of twenty- four hours the thrush patches appear on the inside of the cheeks and then extend to the lips, tongue and palate. While extending, they increase in size, though they usually remain isolated and rarely overstep the limit of the posterior border of the soft palate. With the appearances of the patches, there is increased fretfulness, more pain on sucking, occa- sional vomiting and frequent evacuation of the bowels, the motions becoming green and acid. At some period, varying from six to twelve days from the beginning of the disease, the patches become loose and are removed by the act of sucking or in making applications to the mouth. The mu- cous membrane is left red but free from ulceration, and it soon returns to the normal condition. At the same time the general symptoms subside, and health is soon restored. 6 82 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. Sometimes there are several crops of the fungus, but those coming last, being less firmly rooted than the first, are dis- lodged quickly and seldom prolong the course of the disease beyond two or three days. In secondary thrush a history of previous gastrointes- tinal or other disease will be obtained, together with an ac- count of an immediately preceding diarrhoea and fever. Sometimes, however, the local symptoms are the first indica- tions that the weak, badly-nourished child is ill. The pre- liminary catarrh of the mouth is very marked, the mucous membrane being intensely red and shining. The patches are thick, are apt to change from a white to a yellow or brown color, soon cover the whole oral cavity and frequently extend into the pharynx and down the oesophagus. They retain their attachment to the mucous membrane for a much longer period than in the idiopathic form. When they fall off they are quickly replaced by others, and a succession of crops is the rule up to the termination of the case in death. The mouth is hot, dry and tender to the touch, and through- out presents an acid reaction to chemical tests. The appetite is gradually lost ; there is vomiting, either occasional or so constant that every morsel of food taken into the stomach is rejected at once, and obstinate diar- rhoea, the stools being numerous, liquid, green in color and acid. The abdomen is distended by flatus, and is ten- der to pressure, particularly in the epigastrium and right iliac region. Colic is a constant and annoying symptom. The pain is most severe just before or at the moment of an evacuation of the bowels. The skin is hot and dry and the frequency of the pulse increased, a rate of 120, 140 or 160 per minute being not unusual. The child sleeps badly, is restless and fretful, and when AFFECTIONS OF THE MOUTH AND THROAT. 83 the pharynx is covered by the fungus, has a muffled, hoarse cry. The skin grows pale and inelastic, and the folds of the nates, the inner surface of the thighs and the heels are red- dened, and eventually excoriated by the contact of the acid faeces. The strength and flesh are lost rapidly, the anterior fontanelle sinks, the eyeballs lie deep in their sockets and the nose and chin are pointed. Toward the latter end of the attack, which is rarely protracted more than a few weeks, the patient assumes the facies of a little, wrinkled old man. His skin is cool, and he lies in an apathetic condition on the bed or nurse's lap, with scarcely enough strength to whine over his suffering until death, from atrophy, ends the miserable life. Diagnosis. — Fragments of curdled milk adhering to the soft palate and cheeks, resemble very closely the thrush patches in their earlier stage. The normal condition of the mucous membrane, and the readiness with which the curds can be wiped away, constitute the distinctive characteristics. Aphthous stomatitis bears a certain superficial likeness to thrush, but the differentiation is easily made by noting the fact that the yellowish-white spots of the former are de- pressed below the surface of the mucous membrane, being, in reality, the floors of ulcers, which in time are bounded by dark red borders. Microscopic examination is always the crucial test, and the presence or absence of thallus-fibrils and spores decides the question as to the nature of any deposit in the mouth. Prognosis. — The primary form is a very trifling affection and almost uniformly ends in recovery. In the secondary form the result is very often unfavorable. This is especially apt to be the case when the disease occurs in a child who has been much weakened by a continued course of improper food. Here, the hope of improvement depends upon the 84 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. rapidity and completeness with which new material for nutrition can be introduced into the system. Anything, therefore, that tends to prevent this introduction deprives the child of his only chance of recovery, and the existence of thrush implies a condition of the digestive tract extremely unfavorable to the assimilation of food. Attendant diar- rhoea aids, too, in precipitating the fatal result. The mere presence, then, of the thrush patches is not to be regarded with as much anxiety as the conditions ac- companying their formation. Treatment. — Much may be done to prevent the develop- ment of thrush by keeping the mouth clean. A strict rule should be made to wash out a child's mouth directly after each meal. This is best done by a large camel's-hair brush or a soft rag moistened with warm water. The bottles and tips must also be kept immaculately clean. An equally im- portant precaution is to select a proper diet. The question of diet is, of course, a very comprehensive one, and no further consideration can be given it in this place than to state the general law. Babies under six months old, who are unfortunate enough to be deprived of their mother's milk, must be fed upon cows' milk so prepared that it may resemble as nearly as possible human milk. If farinaceous articles be used they must be employed with the object of rendering it more digestible by separating the curd, and not as the staple of the food. The regularity and the length of the intervals between meals ; the selection of the proper quantity of food, and the preparation of each portion im- mediately before it is given, are matters worthy of the most careful attention. * Such measures, together with attention to general hy- giene, constitute an important part of the curative treat- * See Part III. AFFECTIONS OF THE MOUTH AND THROAT. 85 ment after the appearance of the fungus. In idiopathic or mild cases all that is required in the way of general treat- ment will be an alkali combined with a digestant, as in the formula already given for catarrhal and aphthous stoma- titis,* or if the stools be numerous, green and very acid: — R. Magnesii Carbonatis, gj. Syr. Rhei Aromatici, f 3 ij. Syrupi, f J ss. Aq. Mentha? Piperita;, q. s. ad f ijiij. M. S. — Teaspoonful every two or three hours, for a child three to six months old. The local treatment consists in keeping the mouth per- fectly clean. It should be thoroughly washed every hour at least, with a soft rag wrapped around the finger and wet with warm water. Immediately afterward, either one of the following lotions may be applied, upon a fresh piece of rag:— R. Sodii Boratis, gr. xxx. Glycerinae, fgj. Aquae, q. s. ad f ^j. M. R . Sodii Hyposulphitis, gr. x. Aquae Rosa;, fljj. M. It is essential immediately to destroy the rag or other in- strument used in cleansing the mouth or in carrying the lotion. The same principles are applicable to the treatment of secondary thrush. Every means must be employed to arrest the vomiting and diarrhoea, to improve the digestive powers and maintain the strength. There is, however, but one promising remedy for this form of the disease, namely, the employment of a healthy wet nurse. * See page 61. 86 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. 6. DENTITION. The eruption of the twenty milk teeth may, like other physiological processes, be unattended by noticeable symp- toms, but in many instances it is accomplished with difficulty, giving rise to disturbances which, on the one hand, may be so trifling as simply to annoy the infant, or on the other, so serious as to endanger life. Normally the teeth are cut in groups, each effort being succeeded by a pause or period of rest. The following diagram and table show the grouping, the date of eruption, and the duration of the pauses. The numbers, I to 5, in- dicating the groups to which the individual teeth belong and their order of appearance, and the letters, a and b> the precedence of eruption in the different groups. Fig. i. — Diagram showing Eruption of Milk Teeth. 1. 1. Between the 4th and 7th months. Pause of 3 to 9 weeks. 2. 2. 2. 2. Between the 8th and 10th months. Pause of 6 to 12 weeks. 3- 3- 3- 3- 3- 3- Between the 12th and 15th months. Pause until the 18th month. 4. 4. 4. 4. Between the 18th and 24th months. Pause of 2 to 3 months. 5. 5. 5. 5. Between the 20th and 30th months. AFFECTIONS OF THE MOUTH AND THROAT. 87 The pauses are, to say the least, most helpful, giving the infant's system an opportunity to rest after each effort, to recover from any coincident illness and to prepare for the next strain. Even under normal conditions the edges of the gums lose their sharpness and become swollen, rounded and red- dened as the teeth approach the surface At the same time the saliva is increased in quantity, and the mouth is unnaturally warm and the seat of abnormal sensations, evidenced by the tendency to bite upon any object that comes to hand — in other words, there is a condition of mild catarrhal stomatitis. The consequent discomfort, though, is not sufficient to interfere with the child's appetite, good humor, or sleep, and when, after a few days, the margin of the tooth is free, all the local symptoms vanish. Abnormal dentition is manifested either by departures from the laws of development already stated, or by actual difficulty in the process of cutting. The standard rules for the eruption of the teeth may be departed from in three ways : — 1st. The appearance of the teeth may be premature. Children may be born with one or more of their teeth already cut. These are usually imperfect, and soon fall out, to be replaced at the proper age by well-formed milk teeth. Sometimes, however, they remain permanently, as in a case that came under my own observation. Natal teeth are always incisors. Instances of the lower central incisors being cut in the third month are not uncommon. Girls are more apt than boys to cut their teeth early, and, as an early dentition is likely to be an easy one, the occurrence is to be looked upon as fortunate. 2d. Dentition may be delayed. This deviation is more frequently seen and of more consequence than the first. 88 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. Bottle-fed babies, as a class, are more tardy in cutting their teeth than those reared at the breast. With such, though healthy in every respect, a delay of one or two months is a common and not at all a serious event. On the contrary, whatever the method of feeding, if no teeth have appeared by the end of a year, it may be assumed that the child's general nutrition is faulty, or that rachitis is present. Delay does not necessarily imply difficulty in cutting the teeth, though the two conditions are often associated. 3d. The teeth may appear out of their regular order. Bottle-fed infants are most likely to show this irregularity, which is of some importance as an indication of general feebleness. In other instances, however, it is merely a family peculiarity, and as such, bears no special significance. Difficult Dentition gives rise to two classes of affections, viz. : local, and sympathetic or reflex. The third and fourth groups of teeth are most prone to make trouble, and when the child is born at such a time of the year as to bring their eruption during the hot months, illness of some sort may be anticipated. This is often dan- gerous, sometimes fatal, hence the popular dread of the " second summer." Local Affections. — Catarrhal stomatitis, already referred to as a physiological occurrence, frequently becomes greatly intensified, and is sometimes associated with enlargement of the submaxillary and cervical lymphatic glands. Aphthous and ulcerative stomatitis develop much more rarely. Ulceration of the fraenum linguae often takes place after the cutting of the first lower incisors, being due to direct and continuous friction of the sharp, new teeth. Usually a single, flat, round ulcer, the size of a linseed, is formed. The base is yellow and lardaceous, the edges red and infiltrated. AFFECTIONS OF THE MOUTH AND THROAT. 89 At times it is sufficiently painful to interfere with the movements of the tongue, though at others so indolent as to escape notice entirely. Such ulcers, if left to themselves, disappear in from eight to ten days. Their course may be much shortened by touching them lightly with a point of nitrate of silver, and then applying a solution of chlorate of potassium three or four times each day. Another very common condition is an excessive increase in the secretion of the fluids of the mouth, attributable to irritation of the mucous and salivary glands. The constant driveling of this fluid reddens and excoriates the skin of the chin and anterior part of the neck. It also soaks the cloth- ing; and the consequent chilling of the thorax both excites and tends to keep up a catarrhal state of the bronchial and mucous membrane. In this way may be explained the fre- quent concurrence of driveling and severe cough in teeth- ing children. The etiological association is further proven by the fact that if the chest be protected by a piece of oiled silk or other waterproof material, placed inside of the clothing, the cough either does not develop or quickly dis- appears if it has been present. If these two results are excepted, slobbering is not to be regarded as unfavorable, for such children rarely have alarming brain symptoms, or severe intestinal catarrh. The Sympathetic Effects of difficult dentition show themselves in affections of the eyes and ears, gastrointes- tinal disorders, skin eruptions, nervous affections, and fever. Conjunctival blennorrhoea arises frequently during the eruption of the upper canines ; hence the common name, " eye-teeth." This complication may be attributed to an extension of irritation to the antrum of Highmore, the nasal passages, and, finally, to the conjunctiva. The eyelids swell greatly and rapidly, there is difficulty in opening the 90 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. eye, a free secretion of a stringy, translucent mucus, and pain and photophobia ; the ball remains intact. It is distin- guished from true blennorrhcea by frequently being unilat- eral, by its non-contagiousness, and by the absence of the characteristic dark-yellow, thick, purulent discharge. Re covery quickly follows the appearance of the point of the tooth, and no treatment is required beyond cleanliness and the application of dry warmth. Otitis is not uncommon. It is probably due to irritation conveyed from the inflamed gum to the otic ganglion, and thence deflected to the vessels supplying the tympanic membrane. In consequence, this membrane becomes con- gested, and there is great pain. When the irritation persists, suppurative inflammation is developed in the tympanic cavi- ty, the drum is perforated, and pus flows from the external auditory meatus. The treatment belongs to the domain of aural surgery. Simple diarrhoea, with yellow, pultaceous or somewhat greenish stools, is a very common occurrence. It is due either to an intestinal catarrh of mild grade, or to the swal- lowing of large quantities of saliva, the saline constituents of which act as laxatives. Under ordinary circumstances it should not be interfered with, since it is conservative, other complications, especially affections of the brain, being much less likely to arise while it is present. Attention to the diet is necessary. If vomiting be associated or the stools be green, bicarbonate of sodium, or carbonate of magnesium, with an aromatic, may be ordered, and if there be griping it is well to clear out the bowels by a dose of castor oil. The rules are to hold the diarrhoea in check but never arrest it and to avoid the use of opium and astringents as far as possible. There can be no doubt, however, that during dentition the mucous membrane of the digestive tract, sympathizing AFFECTIONS OF THE MOUTH AND THROAT. 9 1 in the oral irritation, becomes more susceptible to such irri- tants as badly digested or improper food, and that a condi- tion of simple catarrh is apt, under such influences, to pass into one of follicular enteritis, with secondary involvement of the mesenteric glands. This is soon followed by general atrophy (marasmus), frequently terminating in death. Hand- fed infants are particularly prone to be so affected. The symptoms are vomiting, the formation of thrush deposits in the mouth, anorexia, thirst, tympanitic distension of the abdomen, diarrhcea, and rapidly increasing emaciation. The very numerous faecal evacuations are liquid, have a pene- trating, cadaverous odor, and excoriate the anus and sur- rounding parts. This condition demands, and too often resists, the most careful treatment.* When vomiting alone occurs as a complication, it may often be relieved, in sucklings, by shortening somewhat the time the child is allowed to lie at the breast, and thus pre- venting over-distension of the stomach. With hand-fed in- fants the same result may be attained by judiciously lessen- ing the quantity of food given at each meal and reducing its strength, by the addition of lime-water. A teaspoon- ful of lime-water every half hour or hour will aid in check- ing the vomiting, and the following prescription is ex- cellent : — R. Liq. Calcis, Aq. Cinnamomi, aa f^j. M. S. — One teaspoonful every half hour or hour, for a child of seven months. Several forms of cutaneous eruption attend difficult den- tition. They usually appear in children with fair, delicate skins, show some hereditary and family tendency, and must be considered of vaso-motor origin. * See sections on the diseases attended by diarrhcea. 92 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. The eruption may be present during the cutting of one set of teeth only, or may continue during the entire denti- tion. In the latter case it improves greatly or disappears in the pauses. The form usually remains unchanged through- out. The varieties that may exist are : — (a) Urticaria. — This consists of the appearance of a varying number of wheals, chiefly on the trunk and extensor surfaces of the limbs. The wheals are slightly prominent, flattened elevations of the cuticle, varying in size from that of a pea to a bean, somewhat paler than the normal skin but sur- rounded by red areolae gradually fading at the periphery into the healthy skin color. They develop suddenly, mak- ing their appearance especially when the child becomes warm in bed, or is overheated, and are the seat of some burning and intense itching. They last a few hours, and disappear rapidly, leaving the epidermis intact, except for accidental injuries occasioned by scratching. Relief comes after a careful regulation of the diet. If the child be bottle-fed the milk must be well guarded with lime-water. If older, and fed on mixed food, it is well to avoid farinaceous articles. The bowels, usually constipated, should be regulated by saline laxatives, and much benefit will result from the use of effervescing citrate of potassium, in doses of one-fourth of a teaspoonful (equal to gr. v), three times daily, for a child of eight months to a year old. The most soothing local application is : — R . Sodii Hyposulphitis g ij-iv. Aq. Rosae, f % :§ xvj. M. This is to be sponged over the wheals at short intervals or applied by moistened compresses. (b) Strophulus. — This presents itself in two forms, strophu- AFFECTIONS OF THE MOUTH AND THROAT. 93 lus intertinctus or red gum, and strophulus albidus or white gum. Red gum consists of an eruption, of prominent, red pap- ules, interspersed with small patches of erythema. The papules are scattered over the whole body, but are most abundant on the face, back of the hands and forearms ; they vary considerably in size, though they are rarely larger than a pin's head ; they are the seat of considerable itching, and after their disappearance there is trifling desquamation. It occurs in successive crops, each crop lasting from seven to fourteen days. In white gum the papules are pearly-white instead of red, and each elevation is surrounded by a faint red areola. These papules are most numerous on the face, neck and breast; they are smaller than the former, but like them appear in crops, which remain about seven days. With the exception of attention to digestion, which is often deranged, little treatment is required. Dusting with bismuth or lycopodium, or anointing with cold cream or simple cerate will relieve the itching. (c) Eczema* — In teething children this affection may be found in any one of its various forms. It may extend over the entire surface or be limited to a small area ; its usual position, however, is the face and scalp. Facial eczema begins with redness, induration and rough- ness of one or other cheek. There is also intense itching, and even at this early stage the child, if unhampered, will scratch the affected part until it becomes raw and bleeding. Soon minute vesicles or pustules form. If the dermatitis be slight the eruption is vesicular. The vesicles may heal spontaneously, or being broken mechani- cally, they discharge a serous fluid which dries into thin * This is the form of skin disease usually covered by the term "tooth rash." 94 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. scales or lamellated crusts. These fall off, leaving a reddened, moist, delicate surface, still intensely itchy, and soon to be covered by another crop of vesicles, which undergo the same changes. If the inflammation of the skin be more severe, the eruption is pustular. The pustules on breaking, exude a material that dries into thick, yellowish-brown crusts, often extensive enough to cover the whole face, except the eyelids and nose, as with a mask. . In hardening, crack- ing is apt to occur, with the exposure of the red and bleed- ing derm. When these fall, or are scratched off, an intensely red, weeping surface is left, which is soon re-covered by a thinner, lighter-colored crust, resembling that seen in the vesicular form. The neighboring lymph glands are always somewhat enlarged and tender. The process of crust- ing and cleaning off repeats itself again and again, fre- quently dragging through the entire dentition, though subject to improvement or even completely healing during the pauses. Sometimes, especially toward its close, the eczema as- sumes the papular form. The disease is attended by sensations of discomfort and tension about the face. The itching is continuous but sub- ject to exacerbations in which it is most difficult to keep the child from tearing the skin with his nails. One often leaves a patient with his face covered by a thick crust, to find him at the next visit with clean, red and moist cheeks scarred by nail-scratches, from which the blood drops upon his clothing. The exacerbations occur chiefly at night. Under the circumstances it is but natural that the little suf- ferer should be restless and peevish, should sleep badly, and, from the latter cause, should gradually fail in health and strength. The appetite, too, is often diminished, the digestive AFFECTIONS OF THE MOUTH AND THROAT. 95 powers impaired, and the bowels confined. There may be slight febrile reaction toward evening. Eczema of the scalp — crusta lactea — -involves at first only a small area, but has a marked tendency to spread. In some cases it appears in the form of minute, disseminated vesicles ; these break and exude their serous contents, which hardens into thin, scaly crusts. If these be removed the skin be- neath will be found to be reddened and moist. In others the vesicles rapidly change into pustules, and when these are broken the puriform fluid dries into thick, yellowish-brown crusts. The underlying skin is red, swollen and painful, and the source of a constant formation of pus, which in dry- ing adds to the thickness of the preexisting crusts. These mat the hairs together, become, day by day, thicker, harder on the external surface and darker in color, from the admix- ture of dust or of blood flowing from wounds caused by scratching. As the hair grows it lifts the crusts from the scalp and the pus finds its way out, running over and ex- coriating the skin of the forehead and neck. From the heat of the head and exposure to the air partial decomposition sets in, attended by a disgusting odor, and in carelessly kept children myriads of lice appear. In well-marked in- stances the crusts completely encase the scalp. The occip- ital and other lymphatic glands are usually enlarged, and occasionally, in strumous children, suppurate. Crusta lactea is no less obstinate then facial eczema. When it runs a protracted course the hair may fall out, but the loss is not permanent. There can be no question as to the propriety of healing eczema of the face or scalp as quickly as possible. The idea that the cure of the rash leads to more serious mischief, as meningitis or hydrocephalus, is merely a remnant of the long abandoned doctrine that disease is due to the presence g6 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. of an evil spirit, which if driven from one place will attack another. The objections of some self-important and misin- formed parents to any local application will usually be over- come by the assurance that the eruption is not to be driven in, but cured as it comes out. Under the best of conditions, however, tooth rash is difficult to cure, and requires both general and local treat- ment. The general treatment demands in the first place attention to the diet. Bottle-fed babies must have their milk well alkalinized with lime-water, and older children must avoid farinaceous and heavy food. Next, conditions of acid dys- pepsia, which, by the way, frequently exist, must be correct- ed by alkalies. Then it is essential to keep the bowels freely moved; for this purpose the following mixture answers well : — R . Magnesii Carbonatis, Manna? Opt., aa gr. xl. Ext. Sennse Fid., Tt\lxxx. Syr. Zingiberis, f^ ss - Aquae, q. s. ad fj|j. M. S. — One teaspoonful once or twice daily, for a child seven months to a year old. Finally, certain medicines may be used with advantage. The emulsion of cod-liver oil and lacto-phosphate of lime in debilitated, strumous or rachitic children ; syrup of the iodide of iron in the anaemic; Fowler's solution when the eruption becomes chronic. For the successful local treatment of facial eczema it is necessary to have many resources at command ; to make frequent changes as the applications lose their beneficial effects, and to persevere in spite of discouragement. Little progress will be made if the child be allowed to scratch the AFFECTIONS OF THE MOUTH AND THROAT. 97 face at will. During the waking hours this is to be pre- vented by careful watching and diversion on the part of the nurse. At night by muffling the hands in thick, soft cloths, or by wrapping a napkin around the body in such a man- ner as to confine the arms, or, better still, by fixing the lower ends of the night-gown sleeves to the diaper, with safety-pins. The latter arrangement allows of some move- ment of the hands but prevents their being lifted to the face. The child quickly becomes accustomed to the partial re- straint. As soon as redness, induration and roughness of the skin indicate the onset of the disease, a mucilage made from sassafras pith (never musty or sour), is to be mopped over the surface with a soft rag, at intervals of an hour, or less. After this has dried for five minutes, a thick layer of the ointment of the oxide of zinc should be gently applied with the finger. If the officinal zinc ointment increase the in- flammation, as it sometimes does in young or delicate- skinned babies, it must be diluted one-half, or even three- quarters, with cold cream. The nose, eyes and lips should be kept clean by wiping them with a moistened cloth, but the affected portions of the face must never be washed. Both the mucilage and ointment greatly relieve the itching, and in mild cases are sufficient to effect a cure. When vesicles or pustules become abundant, zinc oint- ment is still most serviceable, though it is no longer well to use the mucilage. When the former ceases to be of service, one of the following may be tried : — R. Cerat. Plumbi Sub-acetatis, 3 ij. Ung. Aquae Rosae, ^vj. M. R. Bismuthi Sub-nitratls, ^ j — ij. Adipis, gvj. M. 7 98 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. R. Glycerinae, f 3 ij. Adipis, gvj. M. R . Olei Lini, Liquor. Calcis, aaf^j. M. R . Acidi Salicylici, 3 ss. Adipis, gj. M. The first three are more sedative than zinc ointment, the last two more stimulating. Hebra's diachylon ointment, useful in very moist eczema, is prepared in the following way : — , R. Olei Olivae, f-fj. Lithargyri, gij. Coque 1. a. in molle, dein adde. Olei Lavandulae, rr^viij. M. S. — Rub the ointment over the affected spot two or three times daily, or, better, apply upon linen compresses. When the patient does not bear salves well, a paste of oxide of zinc with glycerin may be ordered, and sometimes a dusting powder is beneficial, as : — R. Zinci Oxidi, gj. Amyli, I). M. S. — Dust over the affected part frequently. In such cases, too, lotions act well. For example, the officinal liquor plumbi sub-acetatis dilutus, or : — R. Zinci Sulphatis, gr.j — ij. Aquae Rosae, f 5J. M. R. Sodii Boratis, gr.v-x. Glycerinae, f^j. Aq. Rosae, q. s. ad f ^j. M. AFFECTIONS OF THE MOUTH AND THROAT. 99 In chronic cases, especially where there is hypertrophic thickening of the corium, a tendency to the squamous form, and but little redness, wonderful results will be obtained by using either — J$. Ung. Hydrargyri Ammoniati, ^ j— iv. Ung. Aquae Rosae, q. s. ad ^j. M. S. — Apply three or four times daily. Or this lotion — R . Hydrargyri Chloridi Corrosivi, g r «j _ U« A q u ^ fgj. M. S. — To be penciled over the affected surface two or three times daily. A great point in the treatment is to continue the local applications, not only until the eruption has disappeared, but until the skin has become perfectly smooth, soft and altogether normal. Again, to begin the applications early, as the ease and quickness of cure is in proportion to the acuteness and scantiness of the eruption. Crusta lactea may be cured with more or less rapidity by cropping of the hair, softening the crusts with olive oil, applying a poultice of flaxseed over night, and using an oint- ment containing mercury, as — R. Ung. Hydrargyri Nitratis, 3 j— ij. Ung. Aquae Rosae, q. s. ad ^ j. M. S. — Rub into scalp three times daily. R. Hydrargyri Chloridi Mitis, gr. xxx. Adipis, gj. M. In some instances penciling with the solution of corrosive sublimate, already mentioned, gives better results. When there is intense redness of the scalp, it is often best to begin with oxide of zinc ointment, reserving the 100 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. mercurial preparations until the inflammation is lessened. When the disease becomes chronic, with thickening of the skin, loss of hair, and the assumption of the squamous form, more stimulating applications are indicated, for instance — R. Ung. Picis Liquids, Adipis, aa ^iv. M. S. — Apply thrice daily. R. Saponis Mollis, ^iv. Alcohol dil f 3 ij. Spt. Lavandulae, TTLxv. M. et cola. S. — Rub into the skin by means of a piece of flannel or a brush, to remove scales, etc. Inunctions of cosmoline and vaseline are often most bene- ficial in eczema, and the latter is a good vehicle for the preparations of mercury, zinc, lead, etc. The most dangerous of all the complications attending difficult dentition are the disturbances of the nervous system. These are due to a great increase in the normally excessive susceptibility of the infantile nervous system to reflex influ- ences. They embrace slight spasms of isolated groups of muscles, general convulsions, and motor paralysis. Slight spasms are very common, and are observable chiefly during sleep. They are revealed by upturned eyeballs, and half-open eyelids, exposing more or less of the whites of the eyes ; by contraction of the muscles of the face, causing a smile, and by twitching movements of the fingers and limbs. These manifestations can be prevented and sound sleep secured, by a warm foot-bath at bedtime, with five or ten grains of bromide of potassium. A general convulsion arises suddenly and unexpectedly, and generally begins with tonic spasm of the muscles. AFFECTIONS OF THE MOUTH AND THROAT. 10 1 The head is thrown back, the spine arched forward, the limbs become rigid, and breathing is suspended. Soon clonic movements set in; the face, which is flushed, becomes distorted ; foam, sometimes bloody, appears upon the lips ; the limbs are jerked about; the trunk writhes; the respira- tion is unrhythmical and sighing, and consciousness is completely lost. After a time, as the convulsion ends, the face becomes pale, the lips bluish, and the skin moist. There may be but a single convulsion, lasting a few mo- ments, or there may be a number, varying in duration, and following each other at longer or shorter intervals. In some cases, the child remains in a convulsed condition for several days, passing from one fit into another, with only brief intervals of imperfect calm. Often they pass off with- out leaving any traces, but may be followed by paralysis, strabismus or idiocy, and may terminate in death. The treatment consists in removing pressure from the gums by the use of the lancet, and the employment of nerve sedatives, as chloral and bromide of potassium. Should it be impossible for the patient to swallow, these drugs may be administered by the rectum, in the following enema : — R. Chloral Hydrate, gr.xij. Potassii Bromidi, % ss. Mucilag. Acaciae, f t ^j. Aquae, < . q. s. ad f Jiij. M. S. — One tablespoonful for a dose. The injections are to be repeated every half hour — at the age of one year — until the convulsive movements are checked, or three or four doses are given. If this quantity fail, it is better to omit the chloral for two hours, and then resume it as. before ; in the meanwhile continuing the bromide of potassium. 102 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. Dental paralysis is sudden in its onset. After a restless night the child wakes with one arm helpless, or with one arm and one leg powerless ; more infrequently one arm and both legs, or both arms are affected. Generally the paralysis disappears after a few weeks. The means for relief are salt- water baths with frictions, attention to the general health, and the use of tonics. Elevations in temperature, with other evidences of slight febrile reaction, are very common during teething. The pyrexia is of short duration, moderate in degree, and readily controlled by hot foot-baths, and diaphoretics, as sweet spirit of nitre or citrate of potassium. In both classes of affections arising from difficult denti- tion, the question of the propriety of lancing the gums often arises. Many authorities advise postponement of incision until the gum becomes swollen, tense and shining, and the edge of the tooth is perceptible to the touch, just beneath the mucous membrane, or until yellowness of the gum and fluctuation indicate the formation of pus about the approaching tooth. This rule applies merely to cases in which there is little difficulty. For in many instances the greatest discomfort and danger are present while the tooth is yet some distance from the edge of the gum, forcing its way through the deeper and denser tissues. Here the only safe course is to cut deep, and liberate the tooth, repeating the operation if the original incisions heal — an event of little moment. My own practice in regard to lancing is guided entirely by circumstances. If there be fever, nervous irrita- bility, sleeplessness, vomiting ordiarrhcea during the progress of and dependent upon dentition, I invariably lance the gum, — provided the position of the tooth can be established by the touch — making the incision superficial or deep, accord- ing to the distance of the tooth from the surface. I feel AFFECTIONS OF THE MOUTH AND THROAT. IO3 confident that no one who has once attempted early lancing, and observed distressing and dangerous symptoms rapidly disappear, will ever hesitate a second time. The form of incision is important. It must be linear in the case of the incisors and canines, and obliquely crucial in that of the molar teeth ; the tissues must be divided until the edge of the lancet distinctly touches the tooth. 7. SIMPLE PHARYNGITIS. Catarrh of the mucous membrane covering the soft palate, tonsils and pharynx — simple or erythematous phar- yngitis — is a common occurrence in children who have reached the third or fourth year, though it is rarely met with before that age. It may either be primary or secondary in origin. The Anatomical Lesion is hypersemia of the affected mucous membrane. This is red, swollen, softened, granu- lar, and at times cedematous. Etiology. — The primary form is most prevalent during the winter and spring. Impaired health, from neglect, bad food, or insufficient clothing predispose to an attack ; while sudden changes in temperature and exposure to wet and cold are the chief excitants. One attack is often fol- lowed by others. The disease is not contagious, but many cases often occur simultaneously. Secondary pharyngitis, which will not be studied here, constantly accompanies scarlet fever and measles, and often complicates bronchitis and pneumonia. Symptoms. — An attack of simple pharyngitis of ordinary gravity begins with fretfulness and lassitude ; the child refuses food, and may vomit once or twice. Fever quickly 104 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. follows, preceded by rigors, or, in children nearing the age of puberty, by a single distinct chill. This fever is quite out of proportion to the local symptoms. The temperature in the course of a few hours rises to 102° or 104 F., and often higher; the pulse runs up to 130 or 140 beats per minute ; the respiration is correspondingly rapid, though easy, the face is flushed and the skin dry. The voice becomes thick and husky, and there is a teasing, unproduc- tive, hoarse cough, which may assume a brazen character toward evening. Older patients may complain of dryness and fulness of the throat, of a sensation leading to frequent efforts at deglutition, or of difficulty and pain in swallowing food ; while infants manifest the latter conditions by refus- ing the breast or bottle. An entire absence of these sub- jective symptoms, however, is common. On inspection, the mucous surface of the soft palate, uvula, tonsils and pharynx presents a reddened, tumefied, dry, granular appearance, and may be partially covered with flakes of whitish mucus or muco-pus. The tonsils are somewhat swollen, and at times the uvula is cedematous. The lymph glands about the angles of the jaw are slightly enlarged and tender to the touch. On the second day the fever abates, the temperature often falling to the normal line, but there is an elevation on each succeeding evening until the end of the fourth or fifth day, when the attack begins to subside. In the meantime the local symptoms increase. Throughout, the child is peevish and restless, sleep is disturbed, the tongue is heavily coated, and there is loss of appetite, increased thirst, and a tendency to constipation. In exceptional cases the disease is much more grave in type. These severe attacks begin with vomiting, excessive restlessness or drowsiness, occasionally convulsions, and AFFECTIONS OF THE MOUTH AND THROAT. 105 always high fever, with a temperature reaching 106 or even more, and a rapid and bounding pulse. The affected mucous membrane becomes intensely red and covered with a muco-purulent secretion. All the ordinary symp- toms are intensified, and in addition there may be mild delirium and a flushing of the entire cutaneous surface, suggesting the scarlatinal rash. These attacks vary in du- ration from three to eight days, and, notwithstanding the alarming character of the symptoms, usually terminate in recovery. Diagnosis. — It is quite possible to overlook the presence of pharyngitis on account of the frequent absence of symp- toms calling attention to the throat. Thus the sudden onset of high fever with rapid pulse and respiration and dry cough would, in the absence of difficult deglutition and pain in the throat, suggest an attack of croupous pneu- monia. If, under the same conditions, the pharyngitis be ushered in by vomiting, the fever might readily be referred to a digestive disorder. Such errors are to be avoided only by making a rule to inspect carefully the throat in each doubtful case. A grave case, again, may in the beginning be taken for one of scarlet fever, the resemblance being increased by the uniform flushing of the surface. Distinc- tion is to be found in the different course of the two dis- eases, and the non-appearance of certain characteristic symptoms of the exanthem. Care must be taken not to confound the white or yellow- ish-white patches of mucus or muco-pus adhering to the inflamed surface with diphtheritic membrane. The former can be wiped away easily, leaving the mucous membrane intact. Treatment. — If the case be seen on the first day, it is possible greatly to reduce the severity of the attack by 106 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. giving the child a hot mustard foot-bath,* putting him to bed in a properly-warmed room, and by cautiously admin- istering aconite, with some saline laxative, as a small tea- spoonful of magnesia in a wine-glassful of strong lemonade. Under such circumstances, tincture of aconite root may be given to a child of four years, in doses of half a drop every half hour until two drops have been taken, and subse- quently the same dose every hour until an effect is pro- duced on the pulse, or the heat and dryness of the skin are lessened. When the fever has been reduced in this way, or should the case not be seen until the second day, the following may be ordered : — ]£. Potassii Chloratis, gr. xlviij. Acid. Muriatici dil., fgi. Syrupi, ^E ss ' Aquse, q. s. ad f^iij. M. S. — One teaspoonful every three hours in water, for a child of four years. If the fever returns as evening approaches, this mixture should be discontinued, and another foot-bath and a few doses of aconite given; or some simple diaphoretic may prove sufficient, as spiritus aetheris nitrosi, or liquor potassii citratis, at intervals of an hour during the night. Throughout the attack the diet should consist of milk and farinaceous articles prepared with milk, with a little meat broth as the fever subsides. A daily evacuation of the bowels must be secured, and the child must be kept in bed. Local treatment must not be neglected. If the child be able, he should gargle the throat every hour with a solution * The ordinary strength of such a bath for a child of three or four years is one tablespoonful of mustard-flour to two gallons of water. AFFECTIONS OF THE MOUTH AND THROAT. IO7 of chlorate of potassium, ten grains to the fluidounce. If too young to do this, the same solution should be applied to the throat at short intervals with a mop of absorbent cot- ton. Painting the throat daily with a solution of nitrate of silver (gr. v to f^j) hastens the cure. At the same time it is well to redden the skin of the neck with some such lini- ment as : — &. 01. Terebinthinse, fgj. 01. Olivse, f^iij. M. S. — Apply twice daily. Grave cases require no alteration of this plan. It is well, if there be great restlessness, to repeat the foot-bath, or even to give several full warm baths of ten minutes' duration. If there be intense inflammation of the pharynx the neck should be enveloped in a poultice, or in extreme cases a leech may be applied behind each angle of the lower jaw. Clogging of the throat by tenacious mucus demands an emetic. When convalescence begins the diet must be more liberal, and restoration to perfect health is hastened by administering a bitter tonic, as tincture of nux vomica, or compound tincture of gentian, in appropriate doses, three times daily. 8. SUPERFICIAL CATARRH OF THE TONSILS. In this affection there is a simple hyperaemia of the mucous membrane covering the tonsils, accompanied by moderate swelling of the glands. It is produced by the same causes, and usually occurs as an element, merely, of general pharyngitis. In the exceptional cases in which it 108 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. exists in an isolated form, the tonsils will be found red- dened and moderately swollen, and several yellowish- white points, due to retained follicular secretion, will be seen on their surfaces. The local subjective, and the general symptoms are the same as those of pharyngitis, and they yield to the same measures of treatment. 9. FOLLICULAR TONSILLITIS. In this disease there is, in addition to superficial hyper- emia, a catarrh of the lacunae or follicles of the tonsils. According to the extent of the disease, several or all of the follicles become filled with a yellowish-white, curd-like mate- rial, consisting of epithelium and pus. When thin, this flows away; but, when thick, it is removed with difficulty, collects and distends the lacunae, and may undergo desiccation, or even become calcified. The parenchyma of the tonsils be- comes hyperaemic, and there is an infiltration of serum and a proliferation of the gland cells. Etiology. — The affection is a common one after the fifth year. It is most apt to be met with in the winter and spring, but it may occur at any season. Exposure to wet and cold is usually considered to be the exciting cause, but an attack may quite as frequently be traced to over-eating, associated with excitement and fatigue. One attack pre- disposes to others, and I have seen many patients who are invariably affected after gorging themselves. with rich food, pastry or candy. A combination of all of these causes — so well afforded by that worst of institutions, a child's party — invariably produces a crop of cases. Symptoms. — When due to over-eating, the attack usually sets in on the day succeeding the indulgence. It begins AFFECTIONS OF THE MOUTH AND THROAT. IO9 with headache, lassitude, pain in the back and legs, and more or less rigor. The tongue becomes frosted; there is thirst, anorexia and nausea, often followed by vomiting. Toward the evening of the first day the face becomes flushed, the skin hot and dry, and the pulse rapid. The bowels are sluggish, and the urine is scanty, high colored and lateri- tious. On the morning of the second day the fever abates, but it returns in the afternoon, and this course is maintained foY three or four days, when convalescence is established. In the meantime the anorexia and constipation continue, the patient sleeps badly ; may even be slightly delirious at night, and, finally, is left so feeble that health is not restored for a week or more. When the affection is due to exposure alone, there is less headache and no nausea or vomiting. In other respects the course is similar, though the attack is followed by less prostration. Whatever the cause, the local symptoms are the same. They consist of a sensation of dryness and heat in the throat, repeated efforts to clear the throat, difficult and painful deglutition, increased salivation, a nasal intonation of the voice, and a heavy, offensive breath. On inspection, a catarrhal condition of the palatine arches and pharynx is observed. The tonsils are enlarged, sometimes sufficiently so as almost to meet one another; their enveloping mucous membrane is reddened and swollen, and their surface is dotted with yellowish-white points, corresponding in num- ber, shape and size with the follicles involved. These points are sometimes covered and concealed by muco-pus, and may be surrounded by shallow, circular erosions of the mucous membrane. On pressing the tonsils, ill-smelling masses of varying size and consistency may be pressed I IO DISEASES OF DIGESTIVE ORGANS IN CHILDREN. out. These are also expelled by hawking, or are forced out in deglutition and swallowed with the food. In whichever way removed, they leave the orifices of the follicles more widely open and gaping than in health. There is some tenderness on pressure beneath and behind the angles of the jaw. The Diagnosis is easily made from the appearance of the tonsils, and from the fact that gentle pressure with the finger will force out one or more masses of retained secre- tion — a pathognomonic sign. There is no doubt that these cases are by some classed as diphtheritic, though none but the most inexperienced could confound the numerous yel- lowish-white points, of irregular shape and size, depressed below or projecting beyond the well-defined lips of the fol- licles, with diphtheritic membrane. The Prognosis is always favorable, except that one attack predisposes to others, which may lead to chronic hyper- trophy of the tonsils. Treatment. — If the attack be traced to over-eating, the administration of an emetic would naturally suggest itself as a preliminary. This, however, is rarely necessary, as the initial vomiting empties the stomach sufficiently. Usually, the first steps are to place the child's feet in a hot mustard bath, then put him to bed, and give, according to the age, one or two grains of calomel at once, or in broken doses if there be much nausea. If, on the first night, the fever be high, tincture of aconite should be resorted to ; if more moderate, an effervescing draught, like the following, will suffice : — &. Acidi Citrici, 3J SS - Aquse, f 5 iij. M. S.— Solution No. I. AFFECTIONS OF THE MOUTH AND THROAT. Ill R. Potassii Bicarbonatis, gj. Aquae, f^iij. M. S. — Solution No. 2. A teaspoonful of each solution is to be poured into a table- spoon or glass and taken while effervescing. This draught has the advantage of checking nausea at the same time that it reduces fever. Small pieces of ice should be swallowed at short intervals to relieve thirst and lessen the inflammation of the tonsils, and the food must be restricted to small quantities of milk and lime-water (3 to 1), or weak broths in case milk disagrees. On the second day, it is only necessary to look carefully after the diet, to allow nothing but milk and broths ; keep the patient in bed, and give during the day the following : — R. Pulv. Pepsinse, Sodii Bicarbonatis, aa gj. M. et ft. chart. No. xij. S. — One powder every three hours for a child of six years. The effervescing mixture may still be used in the early night if the fever be high enough to require it. Such measures should be continued until convalescence is established, care being taken to keep the bowels regular. Then the diet may be gradually increased and a bitter tonic given. If the cause be exposure to wet and cold, the general treatment must be the same as for pharyngitis. The local treatment embraces counter-irritation of the skin of the neck ; touching the tonsils once daily with a solution of nitrate of silver, gr. v to fgj ; and frequent gargling with : — R. Potassii^Chloratis, gr.lxxx. Acid. Carbolici, gr. ij. Glycerinse, f^j. Aquae, q. s. ad f 5 viij. M. S. — Use as a gargle every hour. 112 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. io, SUPPURATIVE TONSILLITIS. Quinsy is a rare disease in childhood and is scarcely ever met with before the twelfth year. When it does occur, some family predisposition can generally be traced. Fatigue and exposure are the exciting causes. It is most frequent during spring and autumn. One attack predisposes to others. It may arise as a primary affection or as a com- plication of scarlatinous, variolous or diphtheritic anginas. One or both tonsils may be affected. Morbid Anatomy. — At first there is intense hyper- aemia with serous infiltration of the glandular tissue, and the tonsils sometimes become swollen to more than double their size. The inflammation may now undergo resolution. Otherwise an infiltration of small cells takes place, into and between the follicles, into the inter-lacunar connective tissue, and in the capsule. Retrogression is still possible, or failing this a new formation of reticulated substance takes place resulting in permanent hypertrophy; a frequent termination of repeated attacks in children. If the inflammation be very intense, an abscess forms, but suppuration is not the usual result of tonsillitis occurring before puberty. With these conditions there is always associated general pharyn- gitis and often follicular tonsillitis. Symptoms. — The disease begins with rigors or a distinct chill, followed by sneezing, epistaxis, headache, pain along the Eustachian tube, loss of appetite, and fever, with languor and muscular prostration during the day, and mild delirium at night. Soon the patient complains of dryness and burn- ing in the throat, difficulty and pain in deglutition, and the voice becomes nasal. If the throat be inspected, the mucous membrane of the soft palate and pharynx is seen to be red and swollen, and one or both tonsils are red- dened and enlarged, often presenting several whitish-yellow AFFECTIONS OF THE MOUTH AND THROAT. II3 points of retained follicular secretion. If one tonsil only be affected, the cedematous uvula will be pushed to the opposite side — an important sign. The symptoms gradually increase in severity. The tem- perature ranges from 99 ° or ioo° F., in the morning, to 102 or 104 in the evening, and the pulse from no to 120; but the respiration, though snoring, is little increased in fre- quency. Pain and difficulty in deglutition grow worse ; the voice assumes a peculiar, thick, nasal tone ; the breath has a heavy odor ; the salivary secretion is increased and dribbles from the mouth ; the tongue is heavily furred, and the bowels are sluggish. The child's face wears an apathetic expression, is red or dusky in hue, and there is dulness of hearing. Talking is painful, and so also is any movement of the jaw. On this account it is difficult to obtain a view of the throat ; but if such be had, the tonsils, when both are affected, are seen to be intensely congested, and so much swollen that they meet; or, when only one gland is involved, it often extends a third of an inch beyond the median line. The day is divided between the listless inac- tion of prostration and the uneasy tossing of discomfort, and the night, between the restlessness of fever and the wandering of delirium. What little sleep is obtained is interrupted by snoring. The crisis usually occurs on the fifth day, although it may be postponed until the eighth. If the tonsillitis end in resolution the fever rapidly subsides, disappearing en- tirely in twelve hours ; the local symptoms simultaneously abate and convalescence is rapid. When the inflammation ends in the formation of new tissue and hypertrophy of the glands, the acute manifestations give place to a train of symptoms to be described in the next section. Finally, if suppuration take place, there is a chill followed by high 114 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. fever. The abscess soon points toward the mucous surface of the gland, and is broken by an effort at deglutition or in an examination of the throat. The quantity of pus dis- charged is ordinarily small, and is swallowed, as a rule. After the breaking of the abscess, the child passes at once from a condition of great distress to one of comparative comfort, and strength and health are soon regained. The Diagnosis of quinsy is unattended with difficulty, and the prognosis, so far as life is concerned, is always good, though the danger of chronic hypertrophy must not be forgotten. Treatment. — If the patient can be seen when the pecul- iar tone of the voice, the pain in the line of the Eustachian tubes, and the deflection of the uvula indicate the beginning of tonsillitis, it is possible to abate or, at least, greatly reduce the intensity of the inflammation. For this purpose he must be put to bed, and given a sufficient quantity of wine of ipecacuanha to empty the stomach. Then, properly proportioned doses of tincture of aconite root must be administered every half hour until an effect is produced on the temperature and pulse, and small bits of ice must be swallowed at intervals of ten minutes. At the same time it is well to apply a sinapism to the side of the neck corresponding to the affected gland. * When the case is not seen until later, the indications are to encourage resolution or hasten suppuration, and to main- tain the strength. To fulfil the first, the neck should be enveloped in a poultice, the throat should be repeatedly * Within the past year I have often succeeded in aborting tonsillitis by thoroughly mopping the affected parts three times daily with a four per cent. solution of cocaine. Even in cases where this favorable result was not ob- tained, the cocaine so far allayed pain as to permit liquid food to be swallowed with ease. This is an invaluable aid in the treatment of severe quinsy oc- curring in feeble children. AFFECTIONS OF THE MOUTH AND THROAT. 1 1 5 gargled with warm water, and steam from an atomizer should be constantly inhaled. The strength is to be kept up by administering all the concentrated liquid food that it is possible for the patient to swallow and by using supposi- tories of quinine. The latter may be ordered in this way : — I£. Quinine Bi-sulphatis, gr. xij. 01. Theobromae, 3"j« M. et ft. supposit. No. xij. S. — Use one every four hours, for a child six years of age. On account of the difficulty in swallowing, it is well to avoid ordering any medicine by the mouth except a dia- phoretic, such as the solution of the citrate of potassium, and an occasional dose of some saline laxative. When there is much restlessness or delirium at night, it is well to give bro- mide of potassium, in ten-grain doses, by the mouth or rectum . If an abscess form, a somewhat rough pressure of the finger against the involved tonsil will hasten its rupture. Incision is rarely advisable. After the crisis is past, the diet must be increased and a tonic ordered, as: — R. Tr. Ferri Chloridi, fgj. Quinise Sulphatis, gr. xij. Syrupi Zingiberis, f 3 j. Aquse, q. s. ad f^iij. M. S. — One teaspoonful, in water, three times daily for a child six years old. The subsidence of the tonsils to their normal size is hast- ened by painting them twice daily with : — R. Acidi Tannici, £j. Glycerinae, f5j. M. For prevention, gargles of cold water and astringents, applications of the glycerole of tannin, and measures to maintain a high standard of health, should be employed. Il6 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. ii. HYPERTROPHY OF THE TONSILS. Chronic enlargement of the tonsils is slow in its de- velopment, and must be considerable in degree before giving rise to definite symptoms. Consequently, the dis- ease is rarely recognized before the third or fourth year of life, although its commencement in early infancy is quite possible. It is common between the seventh and twelfth years. Etiology. — Repeated tonsillar inflammation and the irri- tation attending dentition are the ordinary exciting causes, but it may appear spontaneously in children who are out of health, strumous or syphilitic. As the symptoms are aggravated by any passing angina, more cases demand treatment during the winter and spring than at other sea- sons. Symptoms. — The first to attract attention is loud snoring during sleep, due to pressure upon the velum, and obstruc- tion to the passage of air through the posterior nares. At the same time there is a decided nasal twang to the voice. Examination shows marked projection of both tonsils, or, more rarely, of one only; the follicular orifices are widely open and very distinct, and several of them may present the yellowish-white points of retained secretion. The investing mucous membrane is pale, as a rule, but it may be traversed by arborescent blood vessels. Such a degree of hypertrophy and the accompanying symptoms often disappear spontane- ously with the development of the mouth and vocal organs attendant upon puberty. When the glands are so much enlarged that they touch in the mid-line of the throat, there are added to the other symptoms a constant hacking cough with labored respira- tion, and difficulty of hearing, due partially to pressure upon the orifices of the Eustachian tubes, and partly to a state AFFECTIONS OF THE MOUTH AND THROAT. Iiy of habitual congestion kept up in the surrounding parts. The dyspnoea is much worse at night, and the little patient often starts from sleep in a state of terror. It may be so grave as to threaten life and necessitate tra- cheotomy. When enlargement — so great as to almost completely obstruct the passage of air through the nose — has existed from an early age, noticeable anatomical changes take place. The nostrils become extremely small and compressed, while the superior dental arch retains the narrowness of infancy, not allowing room for the teeth, which, in consequence, overlap one another. The palate, also, becomes unusually high and arched. Furthermore, the obstacle to the free entrance of air prevents the lungs being readily filled in in- spiration, so that a partial vacuum is formed between them and the chest-wall, to fill which the external air-pressure forces in the yielding parietes. The effect of external pres- sure is most marked where the resistance is least, namely, at the base of the thorax, and a constant and long-continued repetition of this leads to the production of a gutter of vari- able depth and three or four inches in width, extending laterally from the lower part of the sternum, and to a pro- jection forward of this bone. Any tendency to pulmonary phthisis is increased by this deformity, and if tubercular disease be present, the impediment to the entrance of air, and the constant irritation of the air passages, maintain a condition most unfavorable to its arrest. Treatment. — Moderate enlargement of the tonsils in a weakly child will often disappear when puberty is passed, or as health is regained under a course of tonics. The best tonic is syrup of the iodide of iron, in doses of ten drops three times daily for a child of eight years of age. It is I 1 8 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. well to paint the tonsils once every day with one of the fol- lowing astringents : — R. Tr. Ferri Chloridi , fgj. Glycerinae, q. s. ad f5j. M. R. Liq. Iodinii Comp., f ^ ij. Glycerinae, q. s. ad f5j. M. When there is marked hypertrophy, I have often had the most successful results from the application of solid nitrate of silver every other day. In making this application, a sharp point of lunar caustic should be thrust into several of the follicles of each gland, and then so thoroughly applied to the whole mucous surface as to leave a thin, white pel- licle. A gargle containing tanic acid must be used four times daily, as : — R. Acidi Tannici, gss. Glycerinae, f J ss. Aquae, q. s. adf^viij. Syrup of the iodide of iron should be given three times daily, care being taken not to administer it at the time that the gargle is used. Cod-liver oil is also serviceable. Together with this treatment enough nutritious food must be given to keep up the strength. This can be done with readiness, since, in spite of the size of the tonsils, there is usually no pain, and little difficulty in swallowing. Excision must be practiced when there is excessive en- largement, provided the above measures of reduction have been thoroughly tested without avail, or if, at any time, there is dangerous interference with respiration. Con- stant or frequent cough, or the presence of any other symptom suggestive of phthisis, also demands an immediate operation. AFFECTIONS OF THE MOUTH AND THROAT. I 19 If, after removal of a portion of the tonsils or their re- duction by treatment, the chest is slow to regain its natural form, the use of light dumb-bells and carefully regulated gymnastics are of much service. Dupuytren's method of reducing the sternal prominence by placing the child's back against a wall, and pressing it firmly backward with the palm of the hand during each act of expiration, is efficient, notwithstanding its apparent roughness. 12. RETROPHARYNGEAL ABSCESS. Abscess behind the pharynx is an uncommon disease; so rare is it, indeed, that in many years' experience at the Chil- dren's Hospital I have seen but one case, and this, unfor- tunately, passed from observation before its termination. Its occurrence is not limited to any age. It results from direct injury; from disease of the cervical vertebrae; as a sequel of fever ; or, more frequently, arises idiopathically. The symptoms are difficulty in swallowing and breath- ing, with a peculiar sound during the latter act. On lying down the respiratory embarrassment is increased, sometimes to such an extent as to threaten suffocation. There is, also, great stiffness of the neck, retraction and immobility of the head, and a diffuse swelling of the lateral cervical surfaces, often greater on one side than the other. If now the finger be carried over the root of the tongue, and down toward the pharynx, a firm or fluctuating swelling will be felt, more or less filling the pharyngeal canal, and projecting over the opening of the glottis. On inspecting the throat, the swell- ing can usually be seen, occupying one or other side or the middle of the pharynx, and pressing forward the uvula and soft palate. The investing mucous membrane may be 120 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. normal or congested. Sometimes the mouth cannot be sufficiently opened to permit of inspection, and at others the abscess is seated so low in the pharynx that no tumor can be seen. Duparcque enumerates three symptoms indicating the formation of an abscess behind the oesophagus, viz. : Severe pain, produced even by moderate pressure on the larynx and upper part of the trachea. The entire suspension of respiration by such pressure. Displacement of the larynx forward and to the right. Fever and cerebral manifestations may or may not be present, and initial symptoms are far from being uniform, so that, unless an examination of the throat be made, the disease may be overlooked in its early stages. Ordinarily, however, the diagnosis can be made without difficulty. Dr. West, describing the lesions in one of his cases, states : " Immediately on dividing the cervical fascia on the right side, a quantity of thick, yellow, healthy pus passed out. This matter had burrowed close to the oesoph- agus, to within a little more than an inch of the clavicle, and also in an oblique direction behind the oesophagus toward the left side, completely detaching it from its con- nections on the right side, though not on the left. It passed up behind the oesophagus and pharynx quite to the base of the skull, a few threads of cellular tissue bathed in pus being all that remained of their posterior attachments. The tonsils were not enlarged, and the glottis was neither red nor swollen, but quite natural." The prognosis is very grave when the disease accom- panies cervical caries ; under other circumstances it is fa- vorable. When untreated, the course is prolonged, as the abscess is slow to break spontaneously. Suffocation from the sudden discharge of pus is an exceptional event. AFFECTIONS OF THE MOUTH AND THROAT. 121 The treatment is simple. As soon as the abscess has formed, it must, when within easy reach, be punctured by a bistoury, the blade of which has been carefully wrapped with adhesive plaster to within a fourth of an inch of its point. If the abscess be situated low down, a trocar and canula is the safer instrument to employ. For several days after the operation, occasional pressure must be made by the finger on the tumor to ensure thor- ough evacuation of the pus. At the same time a general tonic and supporting treatment is advisable. CHAPTER II. AFFECTIONS OF THE STOMACH AND INTESTINES. The fact that hyperaemia is the acknowledged condition of the gastro-intestinal mucous membrane during digestion, and the easily appreciated readiness with which this hyper- aemia may pass from a normal to an abnormal degree under the influence of such apparently trifling irritants as food in excessive quantity or of improper quality, has led me to doubt the existence of what is usually termed " simple indi- gestion" or "functional dyspepsia." The doubt has been strengthened after years of special study of this class of affections in children, and I am now disposed to attribute all forms of disordered digestion to a distinct tissue lesion. This may be, and usually is, a simple catarrh ; but it is none the less a lesion. The fact of its leaving no traces after death, when this event has occurred from other causes, is a poor argu- ment, for no one expects to be able to detect the lesions of simple pharyngitis, for instance, under like circumstances. In consequence of this belief, I have departed somewhat from the usual plan of classifying diseases of the digestive tract. i. ACUTE GASTRIC CATARRH. This is one of the most common ills of childhood, since, in addition to arising idiopathically, it attends every disease in which there is pyrexia, as well as many of those that are apy retic. 122 AFFECTIONS OF THE STOMACH AND INTESTINES. 1 23 The Idiopathic Form may occur at any age, but is in- frequent in breast-fed infants. Its origin under such cir- cumstances is always traceable to some abnormal condition of the mother's milk. The ordinary predisposing causes are dentition, general feebleness of constitution, exposure, and imperfect hygiene. Exposure is also an excitant, but the chief of this class of causes is the administration of food that is either bad in quality or excessive in quantity. An attack, too, sometimes directly follows the use of emetic doses of antimony, sulphate of copper or ipecacuanha. The Anatomical Lesion is hyperaemia of the mucous membrane of the stomach, producing an increased secretion of mucus, and a diminished flow of gastric juice. Symptoms. — An attack of what the nurse calls " indiges- tion" comes on in infants after a bottle of changed milk or a "taste" of some unusual food has been given; in older children after a mixed and indigestible meal, particularly when this has been attended by exposure and excitement. The child, after a few hours, becomes listless, has a hot, dry skin, loses appetite, is thirsty, sleeps restlessly, and, if old enough, complains of headache, abdominal discomfort and nausea. Then there is vomiting of sour-smelling, curdled milk, or of whatever food is in the stomach in a more or less imperfectly digested state. The first act of emesis is easy, but if repeated, as is often the case, there is painful retching, and nothing is expelled save a little bile-stained mucus. Soon the tongue becomes covered, except at the very tip and edges, which are red, with a thick white or yellowish-white fur, through which the fungiform papillae protrude as bright scarlet points. The breath has a heavy or sour odor. There is some fever, the temperature ranging from one to three degrees above normal, and the pulse counting no or 120 per minute. There is moderate ten- 124 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. derness on pressure in the epigastric region. The bowels are confined, and the urine is lessened in quantity and late- ritious. These symptoms continue from twenty-four to forty-eight hours. The attack sometimes terminates suddenly, with several loose faecal evacuations. In other cases the fever gradually subsides, the nausea and thirst diminish, the tongue cleans, and the appetite slowly returns ; convalescence extending over a period of two or three days. The Diagnosis is readily established by the history of the causation, the character of the vomit, the state of the tongue, the moderate fever, the epigastric tenderness, and the course of the attack. The Prognosis is always favorable so far as recovery is concerned, but it must be remembered that one attack always increases the susceptibility to another. Treatment. — Complete rest, on the nurse's lap for in- fants, and in bed for older children, is essential. During the first twelve or twenty-four hours there is no inclination for food, and if any be forced it is quickly rejected. Con- sequently, it is better to avoid any attempt at feeding until the stomach becomes settled. Thirst is to be relieved by ice, swallowed in small bits at short intervals, and by fre- quent small draughts of iced carbonic acid or Vichy water. Such measures are also useful to allay nausea and vomit- ing, but if these symptoms are at all obstinate, a mustard sinapism, just strong enough to redden the skin, should be applied to the epigastrium, and the following prescription ordered : — R. Liquor. Calcis, Aquae Cinnamomi, aa f^ij. M. S. — One to two teaspoonfuls, according to the age, at inter- vals of 15 to 30 minutes, as necessary. AFFECTIONS OF THE STOMACH AND INTESTINES. 125 Frequently repeated small doses of the effervescing citrate of potassium, or of the effervescing draught already mentioned (page 1 10), are efficient. A good plan, too, is to divide the contents of both packages of a Seidlitz powder into a number of equal parts, about twelve for a child of three years ; dissolve a portion from each in a small table- spoonful of water, pour them together and administer in a state of effervescence. This may be repeated, at first, every half-hour, later at longer intervals ; rarely more than six or eight doses are required to check the vomiting. This method has the additional advantage of acting gently on the bowels. In those exceptional cases in which, after an unsuitable meal, there is headache, fever, epigastric discomfort, and nausea without vomiting, it is necessary, as a preliminary measure, to induce emesis by draughts of warm water or a sufficient dose of syrup or wine of ipecacuanha. When vomiting has ceased and nausea disappeared the patient must begin to take food. At first one ounce of sound milk diluted with half an ounce, or even an ounce, of lime-water or barley-water may be given every two hours ; and the quantity increased and the dilution lessened as the stomach regains its functional powers. Weak mutton, veal, or chicken broth, free from grease, and diluted with one-half or an equal quantity of barley-water, sometimes suits when milk cannot be retained. While attention is paid to the diet, care must be taken to secure a free evacuation of the bowels by a mercurial followed by a saline laxative. Beyond this all that is required is to administer properly proportioned doses of bicarbonate of sodium and pepsin before each meal, for three or four days, and to gradually increase the diet to its normal standard as healthy digestion is restored. 126 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. 2. CHRONIC GASTRIC CATARRH. This affection presents so many points of dissimilarity, according to the age of the patient, that it is desirable to study it under two heads, namely, chronic gastric catarrh in infants, and chronic gastric catarrh in children who have passed the period of first dentition. Further, since chronic catarrh of the stomach is always attended by im- perfect gastric digestion, and since food imperfectly digested in the stomach is unfitted for intestinal digestion, and must act as an irritant and lead to intestinal catarrh, it is impos- sible to absolutely isolate the two conditions in a clinical description. This is so markedly the case in older children that it seems best to defer the study of the second division of the subject to a later section headed " chronic gastro- intestinal catarrh," and at present to consider only — CHRONIC GASTRIC CATARRH IN INFANTS. This dangerous affection, sometimes termed " chronic vomiting," is of common occurrence. Morbid Anatomy. — In the earlier stages there is a simple hypersemia of the gastric mucosa, but a long contin- uance of this condition thickens and loosens the mem- brane, changes its color to an ashen-gray, and leads to an excessive formation of tenacious mucus or muco-pus, while greatly lessening the secretion of efficient gastric juice. Coincident enlargement of the gastric glands also gives the appearance of roughness to the surface of the mucous membrane. Etiology. — The period of life between the third and sev- enth months furnishes by far the greatest number of cases. Sex and season are not influential. Infants fed entirely at the breast are very rarely affected. The predisposing causes belong to the class of influences AFFECTIONS OF THE STOMACH AND INTESTINES. \2J that lowers the readily depressed vitality of early infancy ; for instance, over-crowding, filth, want of sun-light and fresh air in dwelling-rooms, insufficient clothing, and too early weaning. The one great exciting cause is the administration of un- suitable food. Sometimes the breast-milk departs so much from its normal quality that it acts as an irritant upon the delicate mucous membrane and produces catarrh ; or it may flow so freely that the child swallows more than he can digest, and the surplus, having undergone chemical change in the stomach, produces a like result. But the harm com- monly arises from the use, in artificial feeding, of food that is either, by its nature, unsuited to the feeble digestive ability of infancy, or which, though good in itself, is rendered hurtful by being kept in unclean vessels, and given from foul or badly constructed bottles. Of the first or essentially bad articles of diet, the farina- ceous foods are the most harmful, because, for the digestion of starch, both saliva and pancreatic juice are required, and these secretions are absent until the fourth month and not fully established for some time later. Further, when sub- jected to the action of a ferment, as mucus, in the presence of heat and moisture — conditions existing in the stomach — these substances readily undergo fermentation resulting in the formation of acid which acts as an irritant to the susceptible mucous membrane. Consequently, such a diet used, as it too often is, to the exclusion of milk, must be a very active cause of gastric catarrh. The habit of allowing or encouraging infants to bolt bits of table-food and drink tea is quite as injurious; perhaps, though, this indiscretion is more apt to produce chronic diarrhoea than chronic vomiting. Perfectly pure milk will be quickly changed and rendered 128 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. irritating and unfit for use by being poured, when delivered by the milk-man, into pitchers or cans not properly cleansed from the remains of the supply of the day be- fore. The smallest quantity of sour milk is sufficient to rapidly produce a like change in several pints of the fresh fluid when mixed with it. The same is true of un- clean bottles and tips to which the dregs of former meals adhere in the form of small white curds. In these the change begins as soon as the fresh milk is added, and advances far before the child finishes the meal. A knowledge of the etiological factors explains why by far the greatest sufferers are foundlings, foster-children, children born to poverty, and those belonging to women who engage themselves as wet-nurses, or are obliged to earn their living by working away from home. Symptoms. — The first symptom is vomiting, occurring at irregular intervals, and resulting in the expulsion of curdled, sour-smelling milk, or whatever food is in the stomach, stained yellow or green by bile. The characters of the vomit, however, soon change, the bile disappearing and only a clear, watery fluid, containing fragments of food, being ejected. In addition, there are eructations of sour or even fetid gas. The surface of the body is normal in temperature or cool, the skin is harsh and sallow, and an eruption of strophulus may cover the trunk and arms. The lips are red and dry, the tongue is coated by a thick, dry, yellow fur, with dull red fungiform papillae protruding at intervals; the mouth is parched, thirst is increased, and milk or water is taken greedily only to be quickly vomited again. The bowels are constipated, and when an evacuation does occur, it is attended by great straining, and the faeces appear in small, round, hard, light-colored lumps, often enveloped in mucus; sometimes moderate diarrhoea alternates. The AFFECTIONS OF THE STOMACH AND INTESTINES. 1 29 abdomen is distended and tympanitic, and there is great ten- derness over the epigastrium. Flesh is rapidly lost, the anterior fontanelle becomes sunken, the child is very fretful, has an aged and anxious expression of face, and a deep furrow may be noticed passing downward from the alae of the nose to encircle the mouth, giving to the lips the ap- pearance of projecting. This condition continues, with occasional brief periods of improvement, for several months. Then the vomiting be- comes more constant, occurring both after food and in the intervals of feeding. It is excited by any disturbance, such a trifling act as wiping the mouth, for example, being suffi- cient to bring on an attack. The stomach seems now to have lost its power to even begin the digestion of the blandest food, for if milk be given, it is vomited uncurdled and in the same state as swallowed. Emaciation progresses very rapidly. The skin, dry and inelastic, hangs in loose folds from the limbs, and is apparently too large for the wasted body. It has a muddy color, and exhales an offen- sive, sour odor. The face is pinched, the eyes are sunken, though bright, with pearly sclerotics; the nose is sharp, and the cheeks hollow. The infant lies with the knees drawn up against the abdomen, and to this position they are at once returned when straightened out; often the legs are moved about uneasily, indicating abdominal pain. There is little sleep either by day or night. Fretfulness is con- stant, with an occasional breaking out into loud, painful cries, or, as weakness increases, into low wailings. The tongue is dry and heavily coated, the bowels continue con- stipated, and, toward the end, the abdomen becomes retracted. The pulse grows weak and frequent in proportion to the failure in general strength, and the temperature falls be- low normal ; the thermometer, placed in the rectum, often 9 130 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. registering but gy° F. The breath is sour, and the scantily secreted saliva, perspiration and urine are all very acid. As death draws nearer, the surface is perceptibly cool to the touch, the hands and feet become blue, patches of thrush appear upon the inside of the lips and cheeks, the little patient lies utterly exhausted, dozing or half unconscious, and for several days, before the fatal termination, the only evidences of life are the gentle rise and fall of the chest in breathing and the occasional expression of pain that flits across the face. Sometimes, in the last few weeks of the attack, certain of the symptoms become exaggerated, constituting what is termed " spurious hydrocephalus." In this condition there is deep depression of the fontanelle, dilated pupils, transient flushing of the face, great languor, heaviness of the head, drowsiness, semi-stupor, and even coma with stertorous breathing. Indications of pain and fever are, however, absent. The sunken fontanelle shows a deficiency in the amount of blood in the brain, but, as suggested by Parrot, there may be, in addition to this source of the symptoms, some toxic element analogous to uraemia. Thrombosis of the cerebral sinuses and intracranial hemorrhages are also occasionally found after death, but their connection with the anti-mortem phenomena are by no means uniform. When the disease terminates favorably the vomiting occurs at longer and longer intervals, and finally stops en- tirely, though there is great liability to a return on the slightest indiscretion. Afterward all the other symptoms disappear except the constipation, which is apt to be obsti- nate. An excessive development of fat is a frequent se- quel. Diagnosis. — The protracted course, the frequent and obsti- nate vomiting of sour liquid, and the excessive emaciation, AFFECTIONS OF THE STOMACH AND INTESTINES. I3I mark the disease with sufficient distinctness. The associ- ation of vomiting and constipation, and the development of the features of spurious hydrocephalus, are suggestive of tubercular meningitis. This disease is to be excluded by the depressed condition of the fontanelle, the regularity of the pulse, the tympanitic abdomen and the apyrexia. Prognosis. — Chronic vomiting is a dangerous affection, even under the best circumstances, and an unfavorable result may be expected when the attack begins during the first three months, or occurs in a child who has been hand-fed from birth. The course is prolonged, extending from two to four or even six months. Treatment. — The first and most essential step in the successful management is a careful regulation of the diet. There are two ends to be attained ; first, to give the stomach as much rest as possible, and second, if a sour odor of the breath and body indicates that fermentation is going on in the viscus, to stop this process by withholding fermentable materials. In cases of moderate severity, where the vomiting has followed premature weaning, with a substitution of farina- ceous food for the natural, a return to the breast is indi- cated. Or, if this be impracticable, the food must consist exclusively of milk guarded with lime-water or diluted with barley-water. For a child of three months a good proportion is two parts of milk to one of lime-water, or equal parts of milk and barley-water. Of either of these mixtures two fluidounces may be given every two hours, though the only guide to the proper quantity is the power of retention ; and if one measure be rejected, less must be given at the next feeding, until the proper amount is ascer- tained. Subsequently, it may be increased as the stomach becomes retentive. 132 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. In more severe and long-standing cases, attended by- symptoms of acid fermentation, it is still advisable, with young infants, to try a return to the breast. In doing this, the fact that the mere act of sucking is sometimes sufficient to excite vomiting must be remembered. So, before dis- carding the mother's milk as a food, an effort should be made to administer it with a spoon, after pumping it from the breast. It may then be retained and digested. However, the majority of patients in this stage of the disease can digest neither breast-milk nor any of the ordinary prep- arations of cows' milk, and time and even life may be saved by adopting at once an unfermentable diet, as a mix- ture of — Whey, .' fgj. Fresh cream, f^ ss. Water, fgj. Or— Weak veal broth (half a pound to the pint), Thin barley-water ; in equal quantities. Either food is best given cold and in small quantities at short intervals. One teaspoonful at a time is enough in bad cases ; but when the amount is so small, the dose must be repeated every ten or fifteen minutes. As improvement occurs, the amount of food and the length of the intervals should both be increased. It is important always to forbid the use of a bottle and feed with a spoon. A careful ob- servance of these details is frequently rewarded by a rapid cessation of the vomiting. After the stomach has been retentive for forty-eight hours an effort may be made to return to a milk diet and the bottle. The change may be begun with what is known among dairymen as " strip- pings." This is the milk obtained by re-milking the cow after the udder has been once unloaded. It contains AFFECTIONS OF THE STOMACH AND INTESTINES. 1 33 much cream and little casein. A combination of this sort : — Strippings, . . fgj. Water, f ^ i j . ; administered every two hours agrees well. This mixture should be used for several days in gradually increasing quantities, until as much as six fluidounces every three hours can be borne with ease, then food, of which ordinary milk is the basis, may be safely resumed. For example : — Milk, f£iv. Cream, f ^ ij. Milk sugar, gj. Water, f^ ij. ; given from a perfectly clean bottle, every three hours. The substitution of lime-water or barley-water for water is advisable in case of slow digestion with colic ; so, too, is the addition of a teaspoonful of caraway-water if there be flatu- lence. Another good combination is — Milk, fgiv. Cream, f ^ ij. Mellin's food, gj. Water, hot, to dissolve the Mellin's food . f^ij. These foods are proportioned for infants of about three months. The importance of preparing each meal sepa- rately, and immediately before it is served, must not be overlooked. The second necessary step is to attend to the clothing and hygiene. A light, long-sleeved, woolen shirt, drawers of the same material, and thick worsted stockings, must be worn ; the latter especially should be insisted on, as it is essential to keep the feet warm. In addition, it is well to envelop the abdomen with a flannel binder. The cloth- ing must be changed at reasonable intervals. Should it 134 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. become soiled by vomit, it must be taken off at once and carried out of the room. The frequency of such accidents can be much lessened by placing a towel under the child's chin and over his chest, to receive the vomited matter. This, too, when soiled, is to be removed immediately and replaced by another, perfectly dry and fresh. The sick- room must be light and well ventilated, and no articles of body or bed clothing moistened with vomited matter should be allowed to remain in it a moment ; the proper tempera- ture is 68° F. If the feet remain cold in spite of stockings, they should be rubbed from time to time with the dry hand, or with some stimulating liniment — oil of turpentine, f^ij, and olive oil, f g ij ; if this does not warm them, the legs, as far as the knees, may be put in a hot mustard foot-bath for five minutes. Hot flaxseed poultices, made light and dashed with mustard, will, when worn over the belly, relieve pain and fretfulness; the same result follows repeated applica- tions of the stimulating liniment. To promote free action of the skin, the whole body should be sponged with warm water twice a day, and afterward anointed with warm olive oil, which must be gently rubbed into the surface with the pulps of the fingers. If there be great prostration, a full bath of 90 F., with or without mustard, may be resorted to, the body being immersed from one to three minutes. Under such circumstances, it may also be necessary to envelop the legs in cloths wrung out of hot mustard water, and to keep bottles or rubber bags filled with hot water in close contact with the body in order to. encourage reaction and maintain a normal temperature. Of medicines, wine of ipecacuanha, in a sufficient dose thoroughly to rid the stomach of acid contents, prepares the way admirably for other measures, but should never be AFFECTIONS OF THE STOMACH AND INTESTINES. 1 35 used when the strength is exhausted. Marked sinking of the fontanelle is always a contraindication. The ordinary means of relieving gastric irritability are of little avail in checking the vomiting in chronic catarrh of the stomach. The remedy that seems to possess most power to accomplish this is liquor potassii arsenitis. The proper dose for a child of three months is half a drop, three times daily, administered simply in a teaspoonful of water or combined with an alkali and aromatic, as : — R. Liquor. Potassii Arsenitis, lUxij. Sodii Bicarbonatis, gr, xxiv. Aquae Menthse Pip., q. s. ad f 5 iij. M. S. — One teaspoonful, in a little water, three times daily. When Fowler's solution fails there are three other drugs that may be tried. These are vinum ipecacuanhas, in drop doses every three hours ; calomel, one-sixth of a grain, every four hours ; and tinctura nucis vomicae, half a drop three times daily, combined with bicarbonate of sodium and an aromatic, as in the prescription just given. While these medicines are being administered, the bowels should be evacuated by laxative enemata. Prostration demands stimulants. The best is old whis- key, which may be given in ten-drop doses every two hours ; but the guide for the dose, as well as for the proper time to commence administration, is the condition of the fontanelle. When convalescence begins, half a drop of tincture of nux vomica, or fifteen drops of the ferrated elixir of cin- chona, may be prescribed, and the tonic effects of fresh air and sun-light must be utilized by taking the child out of doors when the weather permits. I36 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. 3. CHRONIC GASTRO-INTESTINAL CATARRH. This disease is common in children who have passed the first dentition, and bears to them somewhat the same rela- tion that chronic vomiting does to infants. Among the latter it is very uncommon, perhaps because the anatomical position and greater irritability of the stomach in the early months of life favor the rapid expulsion of improper or partially digested food, and the irritating products of gastric fermentation, which would otherwise, as in older children, pass through the pylorus and induce catarrh of the intesti- nal mucous membrane. The disease is met with in two forms, differing merely in the degree of catarrh. For con- venience, they may be considered separately ; as, habitual indigestion, in which the catarrh is moderate in degree; and mucous disease, in which it is intense. HABITUAL INDIGESTION. In the rare cases of this disease where death has re- sulted from an intercurrent affection, post-mortem ex- amination has revealed the gastro-intestinal mucous mem- brane, finely injected, reddened in patches, flabby, swollen and covered with a layer of tenacious mucus of variable thickness. In the majority of cases, though, it is probable that the catarrh does not extend beyond the grade that would leave no gross change after death. Etiology. — The predisposing agencies are deficient functional activity of the stomach, either existing simply as a factor of a weak constitution, or resulting from previous disease or ill-directed hand-feeding. Residence in large cities, and dark, close and damp houses ; too little out-door exercise, and too much confinement and pushing at school ; and finally, the eruption of the permanent teeth, belong to this class of causes. They all act by lowering the AFFECTIONS OF THE STOMACH AND INTESTINES. 1 37 capacity to digest, and the best food imperfectly digested undergoes chemical changes rendering it irritant and capable of transforming the normal hypersemia of digestion into the congestion of catarrh. Fewer cases are met with in summer than in winter, because during the former season children live more out of doors, and the functions of the skin are more active, keeping a larger quantity of blood at the surface — a great safeguard against catarrh. Season, then, may be added to the predisposing influences. The prime exciting cause is unsuitable food. As a rule, especially with children of the poorer classes, among whom the disease is very rife, the fault lies in the food being too strong. These children are allowed to sit at table and par- take of whatever the elders eat, such as meat two or three times a day, with potatoes, bread and butter and tea, none too well prepared or of too good quality. This coarse food, of itself irritating to the delicate lining of the stomach, is also very difficult to digest. The child may have force enough to maintain a fair degree of health against this odds for a while, and some even win in the race, but for most, the time of trouble surely and soon comes. Some portions of the food begin to escape, more or less com- pletely, the solvent action of the gastric juice. The starches and fats, influenced by the heat of the parts and the organic matter present, undergo fermentation, and are converted into acids with the liberation of carbonic acid gas ; the albuminoids become partially decomposed and acrid. These not only irritate the mucous lining of the stomach, but passing into the intestine, act upon its mucous membrane, and cause the same catarrhal lesions there. At first an attack of vomiting and purging, by cleaning out the alimentary canal, puts an end to the catarrh, and the patient is free from symptoms so long as the resulting I38 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. anorexia restricts his appetite. But a return to the old diet is quickly followed by a relapse, culminating in another natural effort at relief, and so the attacks recur, growing more and more frequent and easily induced, until what was originally an acute and passing indigestion becomes chronic. As soon as the catarrh is established and the interior of the canal is covered with tenacious mucus, the disease begins to react upon and increase itself. For, whatever food is taken is soon enveloped by mucus, and this coating prevents the free access of the gastric and intestinal juices, which are solvents and antiferments. Mucus, too, is in itself a powerful ferment and increases the formation of irritating substances ; further, by covering the interior of the alimentary canal, it prevents the absorption of what little food is digested, leading to malnutrition, with a deteriora- tion in the quality of the gastric juice and succus entericus, and leaving more material for chemical change. Thus there is a direct and an indirect reaction. Well-to-do children are spared a coarse diet and, in con- sequence, do not suffer so severely. In them bad food takes the form of rich dishes, pastry, sweets and so forth. Exposure to wet and cold has some excitant influence, though, without the aid of bad diet, it is scarcely sufficient to induce an attack. Symptoms.— When the disease is fully developed, the pa- tient has a spare, delicate appearance, the face wears a lan- guid expression and is pale ; the pallor at intervals increas- ing very much, or again giving place to flushing of one or both cheeks. The hair is crisp and lustreless. The con- junctivae are sometimes natural, but more often slightly yellow. The skin is cool, dry and rough to the touch, and somewhat sallow in hue. The pulse is weak, but otherwise unaltered. The mucous membrane of the mouth is less pink AFFECTIONS OF THE STOMACH AND INTESTINES. 1 39 than normal ; the breath has a heavy, disagreeable odor ; the tongue is pale, broad and flabby, frequently indented by the teeth , and covered with a thin, white frosting, which grows thicker, and more yellowish toward the posterior part of the dorsum. Through this coating the enlarged fungiform papil- lae project, and are redder than the rest of the mucous mem- brane, but not so highly colored as in acute gastric catarrh. Moderate hypertrophy of the tonsils can frequently be ob- served, and, as a rule, the cervical lymphatic glands are slightly enlarged. The appetite is variable and perverted, the desire being for highly-seasoned food. After eating, eructations of flatus occur, and small quantities of partially digested food, mixed with thin mucus and intensely sour, are from time to time regurgitated from the stomach. Tympanites is a constant symptom, and when the child is stripped the distended abdomen contrasts markedly with the spare trunk and limbs. Pain is uniformly present. It may be constant or paroxysmal, severe and colicky, or only amounting to dis- comfort, and either general or confined to certain parts of the abdomen. Usually it is paroxysmal, beginning from two to three hours after meals ; if constant, it is subject to exacerbations at these periods. Generally, too, it is only moderately severe, and is confined to the left or right hypo- chondriac region. The reason for this limitation being, that in both positions, but especially in the first, the colon makes a sharp turn where the gases, liberated by fermentation, become lodged. On account of the mucus covering the faecal masses as well as the interior of the bowel, bringing two slippery surfaces together, the peristaltic con- tractions are less efficacious, and constipation results. In- tervals of two, three, or even nine days elapse between the movements, which are attended by considerable straining, 140 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. and result in the expulsion of a small number of dark, hard lumps enveloped in mucus. The urine, at times, is scanty and high colored, at others, over abundant and light colored. The diminution is apt to attend exacerbations of abdominal pain. During the day the child is listless, disinclined to play and easily tired, while at night he tosses about the bed in a dreamy sleep. To the above symptoms catarrh of the nasal and bronchial mucous membranes is often added. It is usual for the even course of the disease to be broken by vomiting and diarrhoea. In such attacks there may be slight fever, the tongue becomes more heavily coated, the appetite fails and thirst is increased. The vomited matter at first is composed of acid, partially digested food, mixed with stringy mucus ; afterward, if there be much retching, of more or less bile-stained mucus alone. The purging, pri- marily, unloads the bowel of a large quantity of lumpy faeces, apparently the collection of several days ; afterward, the stools are made up of mucus and liquid faeces. Such attacks last one or two days, and are followed by a brief period of improvement. The Diagnosis is easy. The Prognosis is favorable, though, when left to itself, the disease runs a protracted course, improving in summer to return in winter. By the general debility that it produces, it opens the way to intercurrent affections, or the develop- ment of hereditary tendencies, and renders both more fatal. MUCOUS DISEASE. This form of chronic gastro-intestinal catarrh occurs much less frequently than the other. It consists of a mucous flux from the whole internal surface of the alimentary canal, AFFECTIONS OF THE STOMACH AND INTESTINES. I4I which interferes mechanically with the digestion and absorp- tion of food, and so impedes nutrition as to suggest the presence of tubercles. The lesions are identical in kind with those of habitual indigestion, but are much greater in degree. Etiology. — The affection usually arises between the fourth and twelfth years, and has the same predisposing and exciting causes as the milder form. There are two conditions, how- ever, under which the disease is apt to arise, namely : the eruption of the permanent teeth, and attacks of whooping cough. The influence of the former is explained by the intimate sympathy existing between the different portions of the digestive tract, on account of which the irritation of the mouth during dentition is reflected throughout the intestinal tract, producing increased secretory activity and greater sus- ceptibility to irritants. During the course of whooping cough, the gastrointes- tinal mucous membrane is always in a catarrhal state. Much of the tenacious mucus expelled at the end of each paroxysm comes from the stomach. When vomiting occurs, most of the matter ejected is mucus, and the stools contain a quantity of the same substance. As the cough subsides, the secondary catarrh usually disappears, but after severe attacks, and in feeble children, it may continue, and pass into mucous disease. Symptoms. — As might be expected from what has already been said in regard to lesions and causation, the symptoms, in the main, are those of habitual indigestion greatly mag- nified. The child is emaciated and muscularly weak. His face is uniformly pale, though subject to great changes in color, and at times a circumscribed crimson flush appears on one or 142 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. both cheeks ; at others, there is so much pallor, especially about the lips, that fainting seems imminent, and, indeed, it does sometimes occur. The eyes are surrounded by bluish circles, which deepen when the face pales. The conjunctivae are muddy, and there is occasional squinting. The skin is markedly sallow, dry and rough to the touch and, by light friction, numerous fine scales of dead epidermis can be removed, and the hair has a lustreless, faded appearance. The cervical lymphatics are noticeably swollen, though painless. The oral mucous membrane is pale. The tongue, besides being flabby and indented by the teeth, presents an ap- pearance characteristic of the disease. The dorsum, with the exception of an oval space in the centre, is covered with a light gray coating, scarcely thick enough to obscure the natural pale-pink color, and shows clearly the slightly redder fungiform papillae. The oval bare spot, about as large as a cent, is still deeper red, and shines as though varnished. This glossy look, in very severe cases, extends over the whole dorsum, and is due to an excessive secretion from the mucous glands of the mouth. Such a tongue does not lose the natural velvety appearance arising from the fungiform papillae. (See a, Plate I.) Chronic hypertrophy of the tonsils, with plugging of the follicles by retained secretion, is common, and, in part, accounts for the disagreeable odor of the breath. The appetite in the beginning fails, then becomes capri- cious, and, finally, almost insatiable. The increased desire for food is due partly to a morbid craving, excited by the irritation of the fermenting contents of the stomach and intestines, and partly to the demand of the tissues generally for more nutriment than is supplied by the imperfect diges- tion and impeded absorption. Eating is followed by a AFFECTIONS OF THE STOMACH AND INTESTINES. 1 43 sensation of drowsiness, and by eructations of flatus and acid liquid. Tympanitic distension of the belly is always marked, and the child complains of pain in this portion of the body. The pain may be general, when it amounts to little more than a sensation of soreness, but more frequently it is limited to the left hypochondriurri, and is stitch-like in character. Either variety may be constant, or present only after meals ; in the former case there is a temporary increase of discom- fort after eating. In some instances, paroxysms of severe pain in the neighborhood of the umbilicus occur early in the morning, and occasionally after meals. These are unat- tended by nausea, purging, or doubling of the body to secure relief, as in colic, but while they last, the pallor of the face is extreme. Constipation is the usual condition of the bowels. Evacu- ations take place at intervals of several days, with much straining, and at times rectal prolapse ; they are scanty, and composed of small, hard, dark-colored lumps, with a large proportion of mucus, and often contain intestinal parasites or their ova. Sometimes the constipation lasts for a week or more at a time, to be followed by a number of free evacuations in quick succession, relieving the bowel of the accumulated faeces; then comes another period of confine- ment, another relief, and so on. By day, the patient suffers from headache ; is languid, ill- tempered, and disinclined for study or play. At night, he is restless ; grinds his teeth ; starts from sleep in terror caused by frightful dreams, and often screams or talks in- coherently, and for a time is seemingly unconscious of his surroundings. Somnambulism and nocturnal incontinence of urine are quite common. Stammering is another nervous symptom occasionally encountered. 144 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. There is no alteration in the temperature ; the pulse is feeble, and there is frequently a slight, dry, hacking cough, entirely independent of pulmonary disease. The urine is diminished during the continuance of severe pain, but is voided in excessive quantities at the termination of the paroxysms. At intervals of two or three weeks violent vomiting and purging occur. During these attacks, which last from one to three days, a large quantity of mucus is rejected ; there is slight fever, and the tongue is changed in appearance, and for the second time assumes a characteristic as- pect. It becomes less flabby, more pointed, and covered with a thick, white, feathery fur, except along the sides, where there are several smooth, bright-red, glazed patches of variable size and shape, with irregular, indented edges. A few red fungiform papillae show through the coating. Sometimes the whole dorsum is clean, red, and glazed, as if denuded of epithelium. (See b, Plate i.) Temporary im- provement follows the clearing-out process, but soon the symptoms return, and slowly grow worse to culminate in another attack. The course of the disease is very chronic, extending over months. There is no regular progression, though the ten- dency is for the symptoms to grow more and more severe as time lapses. Diagnosis. — Tuberculosis is the condition most likely to be confounded with the disease in question, and the mistake is especially apt to be made when a dry, hacking cough is present. The appearance of the symptoms after whooping cough or during second dentition ; the state of the tongue ; the mucous stools ; the condition and color of the skin ; the absence of pyrexia except during the attacks of vomit- ing and purging ; the periodicity of these attacks ; the AFFECTIONS OF THE STOMACH AND INTESTINES. I45 diurnal drowsiness and nocturnal terrors, and the irregu- larity in the course are the distinguishing features. Prognosis. — Mucous disease is not in itself mortal, and is perfectly amenable to treatment. It is, nevertheless, dangerous from its power to reduce the general nutrition, thus opening the way for more serious intercurrent affec- tions. As the plan of managing both forms of chronic gastro- intestinal catarrh is the same, it is unnecessary to divide the subject of — Treatment. — Since the exciting cause is perfectly well known and removable, relief may be confidently promised, provided it be possible to regulate the diet. There are two rules to be insisted upon : first, to stop the supply of all those articles of food that readily undergo fermentation; and, second, to allow only a moderate quantity of food at a time, so as not to overdistend the stomach, while the meals are increased to four a day, to insure the ingestion of a proper amount of nourishment. All farinaceous substances must be excluded from the dietary save stale or toasted bread, and this, even, must be restricted in amount. Potatoes, peas, beans, turnips, carrots, parsnips, fruit, cakes, pastry, sweetmeats and butter are all in the proscribed list. Of permissible articles, milk, eggs and lean meat are the chief, though fresh fish, raw oysters, cauliflower tops, spinach, asparagus, lettuce and celery can be used without ill effect. With such food to select from, it is easy to write out a suit- able diet list and make changes sufficiently often to avoid cloying the appetite by monotony. In writing such lists, it is best to fix the hour, as well as the ingredients, of each meal. For example: — 10 I46 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. Breakfast, at 7 a.m. — One or two tumblerfuls of milk guarded by lime-water* (f3 ij to f,l vj), the yolk of a soft- boiled egg, and a single thin slice of stale, unbuttered bread. Luncheon, at 11 A. m. — A cup (fliv) of beef-tea, or mut- ton broth, entirely free from fat,f and a thin slice of dry toast. Dinner, at 2.30 p.m. — Broiled mutton chop, entirely free from fat, one or two, according to the size ; a large spoonful of well-boiled spinach, and a slice of stale, dry bread. Supper, at 7 p.m. — One or two tumblerfuls of milk guarded by lime-water, and a slice of dry toast. Filtered water must constitute the drink, though, if the child will take it, half a tumblerful of Vichy at luncheon and dinner can be recommended. Should failing appetite demand a change, another menu must be made, as : — Breakfast. — Milk, a bit of boiled fresh fish, and a thin slice of unbuttered toast. Luncheon. — The soft parts of six or eight small oysters, seasoned with salt alone, and a Boston cracker. Dinner. — A bit of the breast of a roasted or boiled fowl, a moderate portion of well-boiled cauliflower tops, and a slice of stale, dry bread. Supper. — Milk and dry bread. Further variety can be had by substituting a thin slice of cold roast mutton or beef for the egg or fish at breakfast ; at dinner, by running the changes on roast mutton, broiled beef-steak, roast beef, plainly cooked game, and such vege- tables as stewed celery, boiled asparagus tops, spinach and * The lime-water is added both for the purpose of retarding coagulation and for its effect upon the mucus in the alimentary canal. f The fat can be completely removed by allowing the broth to stand for a few minutes after it is made, and picking off the globules of oil as they rise to the surface with a fragment of blotting-paper. AFFECTIONS OF THE STOMACH AND INTESTINES. \\J cauliflower; by using different sorts of meat broths, and by changing the manner of cooking the eggs. When, in mucous disease, there is great debility, stimu- lants are indicated. They should be given well diluted and with the meals. Whiskey and old dry sherry are the best. Of the first, one or two teaspoonfuls in a fourth of a tumbler of ice-water may be given with lunch and dinner; of the second, one or two tablespoonfuls with twice as much water at the same meals. Next to regulating the diet it is important to maintain the activity of the skin. This is to be accomplished by baths, inunctions and proper clothing. Each morning the patient, being in a warm room, should be sponged with water at a temperature of 6o° F., then thoroughly rubbed down with a coarse towel, and the whole body anointed with warm olive oil, which ought to be gently rubbed into the skin with the finger pulps. At bedtime a full bath of ioo°, of five minutes' duration, must be given, and the inunction repeated, after careful drying with friction. In severe cases, where the skin is very dry and rough, the first warm bath should contain a heaped tablespoonful of soda, and with this and soap the whole surface must be thor- oughly scrubbed. Woolen underclothing, to cover completely the trunk and limbs, and woolen stockings are to be insisted upon. The weight may be changed with the weather, but not the material. This not only keeps the skin warm, full of blood and functionally active, but it also maintains the heat of the whole body and saves force. Children dressed for beauty with four or five inches of bare leg, nine times out of ten suffer from chronic indigestion or bronchitis. First, because chilling of the surface drives the blood toward the interior and puts the mucous membranes in the most favor- I4o DISEASES OF DIGESTIVE ORGANS IN CHILDREN. able conditions for catarrh ; secondly, because so much force is consumed in maintaining the normal tempera- ture in the face of constant chilling that other functions, notably the digestive, must suffer. Parents would appre- ciate this better if they could be persuaded to try the experiment of sitting, for an hour or so, even in a warm room, in the same degree of nakedness that they inflict on their children, who are less robust and less able to resist cold. Exercise in the open air on suitable days in winter, and an almost complete out-door life in summer, hastens re- covery. The sleeping and living room should be large, light, dry, well ventilated and properly warmed. Medicinal treatment is of minor importance, but by no means to be neglected. The indications to be fulfilled are to check the secretion of mucus ; to neutralize the acids formed by fermentation of the food ; to restore the mucous membrane to a normal condition, thereby improving secre- tion, digestion and appetite ; and to secure regular action of the bowels and the expulsion of collected mucus and faeces. These accomplished, strength and health return, though it may be necessary to call in the aid of tonics. Alkalies are the best remedies to check the secretion of mucus, and to liquify it so that it may more readily be removed. They are also most efficient in neutralizing the acid products of fermentation. Simple bitters, too, have some power in lessening the formation of mucus, and consid- erable influence in arresting fermentation ; at the same time they give tone to the mucous membrane and stimulate digestion. Laxatives keep the bowels clear. Of the first class, bicarbonate of sodium ; of the second, gentian or calumba ; and of the third, senna or aloes, are to be pre- ferred in treating this disease. AFFECTIONS OF THE STOMACH AND INTESTINES. 1 49 In habitual indigestion, a combination like the following will be all that is required. : — R. Sodii Bicarbonatis, gj. Ext. Sennae Fluid., f.^hj. Inf. Gentians Comp., q. s. ad f^iij. M. S. — Two teaspoonfuls three times daily before eating, at the age of seven years.* Should there be yellowness of the conjunctivae and marked sallowness of the skin, indicating a slight degree of catarrhal jaundice, it is well, at first, to substitute equal doses of chloride of ammonium for the bicarbonate of sodium in this prescription. In mucous disease a similar prescription, with minute doses of iodide of potassium to increase the salivary secre- tion, may be ordered before meals, as : — R . Potassii Iodidi, gr. vj. Sodii Bicarbonatis, gj. Ext. Sennae Fid., f 3 iij. Inf. Calumbae, q. s. ad f 5 iij. M. S. — Two teaspoonfuls three times daily before eating. After food, it is well to order from ten to twenty drops of tincture of myrrh in a little water, for its powerful tonic action on the intestinal mucous membrane. Aloes is valuable not alone as a laxative, but in arresting the mucous flux and bracing the mucous membrane. It can be administered in the form of tincture of aloes and myrrh, in doses of twenty drops, three times daily after eating. Or, if the child be able to swallow a pill, it may be combined thus : — & • Pulv. Ipecacuanhse, gr. iv. Pil. Aloes et Myrrhae, gr. xij. Ext. Gentianae, gr. vj. Ext. Taraxaci, gr. xij. M. et ft. pil. No. xij. S. — One pill three times daily an hour after eating. * All of the subjoined prescriptions are proportioned for children of this age. 150 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. When there is much debility iron is demanded, and if the proper form be selected, it may be given in spite of a coated tongue, the usual contraindication. A good formula is : — R. Ferri Sulphatis Exsiccati, gr. xij. Tr. Aloes et Myrrhae, f 3 iv. Syr. Rhei Aromat., q. s. ad f^iij. M. S. — One teaspoonful three times daily after meals. From this prescription there is an astringent action, by the iron and rhubarb, which tends to check the formation of mucus ; a laxative action, by the aloes and rhubarb, keeping the bowels clear of mucus and faeces ; while the myrrh is a direct tonic to the relaxed mucous membrane. If, as the tongue cleans, the improvement under this plan comes to a stand, it is advisable to change to an acid treat- ment. There are several useful prescriptions, for instance : — & . Pepsin. Saccharat., gij. Acidi Muriatici dil., f 3 ij. Aquae Cinnamomi, q.s. adf5iij. M. S. — One teaspoonful three times daily after eating. Or the acid may be combined with a bitter : — R. Acidi Muriatici dil., f 3^ ij- Inf. Gentianae Comp., q. s. ad f^iij. M. S. — One teaspoonful three times daily after meals. R. Quiniae Sulphatis, gr- xij. Acidi Muriatici dil., f^ij- Aquae Cinnamomi, q. s .ad f^iij. M. S. — One teaspoonful three times daily after meals. All of these prescriptions must be well diluted and taken through a glass tube. During the periodical attacks of vomiting and diarrhoea, so apt to occur in both forms of the disease, the child must AFFECTIONS OF THE STOMACH AND INTESTINES. I5I be put to bed, restricted to a diet of milk and meat broths, and ordered the following prescription : — R. Pepsinse Saccharat., Sodii Bicarbonatis, aa 3 j. Pulv. Aromatici, gr. xij. M. et ft. chart. No. xij. S. — One powder four times daily. The diarrhoea must not be interfered with unless it be- come excessive, when it may be held under control by adding five grains of subcarbonate of bismuth to each of the alkaline powders. After the tongue becomes normal and the active symp- toms have disappeared, the general strength must be built up by a course of tonics. The best, are tincture of nux vomica, ferrated elixir of cinchona, and bitter wine of iron. In order to prevent a relapse, mixed diet must be avoided for at least two months after convalescence is fully estab- lished, and to confirm the cure, change of air, by a trip to the sea-shore or mountains, is advisable. Both habitual indigestion and mucous disease are occa- sionally attended by a troublesome symptom that demands brief consideration. This is a peculiar cough, which is dry, paroxysmal, and unattended by lesions of the throat or lungs. The paroxysms commence in the early evening, and may, by their repetition, prevent sleep for half the night. On the following day the patient is as well as usual, or coughs only at long intervals, but about bedtime the trouble begins again. So the symptom continues for weeks at a time, unless its true nature as a "stomach cough" be recog- nized and it is properly treated. The paroxysms suggest those of pertussis, though they may be distinguished by the absence of whooping, and of the characteristic expulsion of tenacious mucus at the end of the kinks. Questioning often 152 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. reveals the fact that the cough is worse after a rich and heavy supper. If proper clothing be worn, the diet carefully regulated, and alkalies prescribed, as for an ordinary case of chronic gastro-intestinal catarrh, improvement is rapid, for in this way the cause is removed. Ordinary cough mixtures do more harm than good, from their tendency to derange di- gestion; still, the fatiguing cough must be relieved. This can be done by letting the child wear a small bean-shaped belladonna plaster over the larynx, and administering a dose of one of the following mixtures every two hours, beginning at four o'clock in the afternoon : — Be . Pulv. Aluminis , gr. xlviij . Potassii Bromidi, ^ij. Syrupi Zingiberis, Aquae, aa f jf jss. M. S. — Dose, one teaspoonful. Or— R. Ext. Belladonnse, gr. ss-j. Pulv. Aluminis, gr. xlviij. Syrupi Zingiberis, Aquae, aa f ^jss. M, S. — Dose, one teaspoonful. 4. ACUTE INTESTINAL CATARRH. The condition intended to be indicated by this title is usually called simple or non-inflammatory diarrhcea, and classed as a functional disease. But from its etiology, and from the fact that in certain patients and under certain cir- cumstances it so readily lapses into entero-colitis, it is more than probable that it depends upon a distinct, though pass- AFFECTIONS OF THE STOMACH AND INTESTINES. 1 53 ing lesion — a hyperaemia or catarrh of the intestinal mucous membrane. This is difficult to demonstrate, partly because the opportunity for post-mortem inspection is rare in simple diarrhoea, and also on account of the well-recognized rapidity with which the appreciable manifestations of mild forms of catarrh disappear after death. Nevertheless, even those au- thors who advocate the functional character of the affection, state that in some instances of death, in feeble children or from intercurrent disease, autopsy shows injection, swelling, and relaxation of the mucous membrane, and tumefaction of the intestinal glands. Etiology. — Constitutional feebleness and unfavorable hy- gienic surroundings, especially residence in crowded, damp, and filthy houses and quarters of cities, increase the liability to attacks of diarrhoea. Many more cases occur in summer than at other seasons of the year. Children of either sex, or of any age, may be affected, though the younger the patient the more serious the disease. In infancy there are numerous exciting causes. Over- feeding, even with healthy breast-milk or well-prepared cows' milk, is one. Ordinarily, in such cases vomiting is so easy that the child gets rid of the surplus and no harm is done; but if this do not happen, the excess remains undigested ; undergoes change ; acts as an irritant to the intestinal mucous membrane, and causes diarrhoea. An- other cause is food of bad quality; either poor and cho- lesterin-laden breast-milk, or unsound cows' milk and farinaceous preparations. Here the action is the same as in over-feeding, though more rapid and violent; this is especially true of the farinacia, on account of their readi- ness to undergo acid fermentation. Again, exposure to cold and wet, by chilling the surface and determining the blood to the interior of the body and mucous membranes, 154 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. may lead to an intestinal catarrh in the same way that it does, more frequently, to a bronchial catarrh. Hyperaemia, too, of the mucous membrane of the alimentary tract is attended by a diminution in the secretion of digestive solv- ents and an increased production of mucus ; two conditions most favorable to incomplete digestion and fermentation of the food with the formation of irritant products. These, as already seen, are quite capable, in themselves, to cause loose- ness of the bowels, and must greatly add to the ill effects of exposure. High atmospheric temperature is much more in- fluential than low, particularly when associated with excessive moisture. Such conditions are powerful depressants to the vital forces ; the digestion shares in the general weakness, and much of the food is left to ferment and become irritant. Finally, dentition is a frequent cause. During this process, the whole digestive tract sympathizes with the condition of the mouth, and becomes less able to perform its functions and more susceptible to irritants. After the eruption of the milk teeth the use of unsuit- able food and the disturbing influences of second dentition are the chief causes. It is almost unnecessary to call attention to the lesson taught by this study of the etiology. There is, on the one hand, the presence of an irritant as a constant factor ; on the other, a mucous membrane naturally delicate and func- tionally very active. The conclusion is inevitable, that the ordinary effect must follow, and hyperaemia or catarrh be produced. Symptoms. — In infants, the attack may begin suddenly, or be preceded for twenty-four hours or more by peevishness, languor, faded cheeks, slight abdominal pain, indicated by moaning or fits of crying, and restless, disturbed sleep. Next, the bowels become disturbed. The movements AFFECTIONS OF THE STOMACH AND INTESTINES. 1 55 number from four to eight in the twenty-four hours, and usually occur only while food is being taken — from six in the morning to ten o'clock at night. At first they differ from the normal, merely in being more liquid and copious, and having a more offensive odor. As the disease pro- gresses they undergo various changes. Sometimes they are composed of a yellowish liquid containing white or yellowish flakes resembling curdled milk. At others, dis- tinct white lumps of undigested curd are mixed with the liquid. Still again, green flakes may appear in a stool having the characters of the first ; and finally, the whole may be of a deep green color, and contain little masses of mucus. In exceptional cases a small amount of bright- colored blood may be seen in the evacuations. Often the movements are preceded, for a short time, by pain, but this disappears as soon as the act is accomplished. Occa- sionally, if the stools be acid, considerable tenesmus attends their expulsion, and it is under such circumstances that blood is most likely to be voided. The tongue is lightly coated ; there is anorexia ; increased thirst, and occasionally nausea and vomiting. The abdo- men is natural in shape, and is soft and painless on palpa- tion. The urine is somewhat lessened in quantity, and high colored. There is no pyrexia, and the pulse is but slightly increased in frequency. The evil effect of several days' continuance of diarrhoea upon the general condition of the child is shown by the pallor of the face, the sunken eyes, the loss of weight and the flabbiness of the muscles. Under proper management the attack terminates in from four to seven days, and strength is soon restored. Simple diarrhoea is more uncommon in older children and much milder in its manifestation. There is slight fur- 6 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. ring of the tongue, loss of appetite, and abdominal pain of a colicky nature, with more or less frequent evacuations of light yellow, offensive, semi-solid or liquid faecal matter, at times containing masses of partially digested food. The patient is weak and disinclined to exert himself. These attacks last for three or four days, and are followed by little constitutional depression. Diagnosis. — There is no difficulty in distinguishing the disease. The only conditions for which it could possibly be mistaken are tubercular diarrhoea and entero-colitis. The former is excluded by the history and course of the case and by lack of evidence of tuberculosis of other portions of the body; the latter, by the apyrexia and the non-existence of symptoms indicating intestinal in- flammation. Prognosis. — The result of even the more serious attacks in infants is, in the great majority of cases, favorable ; never- theless, it must not be forgotten that an acute catarrhal diarrhoea, when it occurs in a weak, ill-fed and badly cared- for child during hot weather, has a tendency to run into entero-colitis, and thus prove fatal. An infant, too, may be so debilitated by previous illness as to be carried off by an attack of ordinary severity. Treatment. — Before entering into the details of the man- agement of this disease, it is necessary to draw attention to the conservative nature of the diarrhoea. The frequent, loose and copious stools clear the intestines of irritant mat- ter, and remove the cause of further trouble. Conse- quently, it is never advisable, early in the course, to com- pletely arrest the evacuations, although at the same time they must be kept well in hand, lest the attack pass into entero-colitis. During dentition, particularly, this caution must be observed, for when there are three or four loose AFFECTIONS OF THE STOMACH AND INTESTINES. 1 57 passages daily, cerebral symptoms are much less apt to arise. . . As in other digestive disorders, the most essential step is to attend to the feeding. With infants nursed at a healthy breast it is enough to see that they are not fed too fre- quently, and to lessen the quantity taken by shortening each act of sucking. If, from any cause, the breast-milk be unsuitable, the babe must be weaned and carefully fed by bottle. In hand-fed babies it is necessary, first, to insist upon the use of the old-fashioned bottle and tip, and to see that they are kept absolutely clean. Next, to banish all farina- ceous preparations, used purely as foods, from the diet. This does not preclude the employment of small quantities of arrow-root or barley-water for the purpose of breaking up the milk curd. Thirdly, to direct that the daily supply of milk — the only food to be allowed — must come from one dairy; be received fresh in the morning, and kept in a separate, per- fectly clean vessel, and, if possible, in an especial refrigerator. And finally, to give careful, written orders as to the man- ner of preparing the milk food, and to make a rule that each bottle shall be mixed separately and only immediately be- fore it is required. In hot weather it is often advisable to boil the whole supply of milk, to prevent its souring, but this does not affect the principle of the separate preparation of each portion. As guides to the manner of preparing the food, two formulae may be given ; they are proportioned for children of four to six months. Unskimmed milk, f^iijss. Cream, f^ss. Lime-water, f^ ij. Mix these in a clean bottle, and warm by standing in hot water. Five to six bottles to be taken during the day. I58 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. Or— Unskimmed milk, f^iijss. Cream, f^ ss - Arrowroot- water,* f^ ij. Sugar of milk, 3J. Mix and treat as before. The quantity is to be reduced and the dilution in- creased in proportion to the youth of the infant, and the reverse as age increases. Sometimes in children of one or two months a cream and whey mixture suits better, as: — Fresh cream, f^j. Whey, fgij. Hot water, f^ ij. When there is thirst, cool water and bits of ice ought to be given with moderate freedom. The sleeping room should be airy, well ventilated, and, in hot weather, the coolest the house affords. Soiled diapers, or the vessel containing a stool, must not be left about. In summer the patient should pass the mornings and evenings in the open air, and the hot mid-day in a cool room. A day's excursion on a steamboat, or to the country, if the journey be short, is very beneficial, while a trip to the sea-shore works wonders ; a single day passed in salt air often removing every trace of the disease. Even in winter, if an attack occur, the child, well wrapped up, should be taken out for an hour at noon on warm, sunny, still days. The daily bath must be continued, and in hot weather a bath morning and evening is none too much. Woolen drawers and shirts of the lightest texture must be worn in * Take one and a half teaspoonfuls of arrowroot, rub it down with a table- spoonful of cold water until smooth, and add, with stirring, a pint of boiling water. AFFECTIONS OF THE STOMACH AND INTESTINES. 1 59 summer, and if the diarrhcea prove at all obstinate, the abdomen must be enveloped in a light flannel bandage. The condition of the mouth must always be investigated, and if the gums be hot and swollen, from approaching teeth, lancing is indicated. If there be much pain, with hardness of the gums, relief can be obtained by rubbing them gently at intervals with paregoric and water, ten drops to the teaspoonful, or with a solution of chloride of zinc, one grain to the fluidounce. When these measures are carefully carried out in mild cases, medicines are often unnecessary. In those more severe, it is well to assist nature and begin the treatment with a laxative. Pain, green stools and the presence of blood always indicate this course. The best laxative is castor oil. This not only efficiently clears away the irritating contents of the intestines, but has a secondary, soothing action upon the mucous membrane. For a child of six months, the dose is a teaspoonful, with five drops of camphorated tincture of opium to prevent griping. After this has operated, a teaspoonful of chalk mixture every two hours will complete the cure in some instances. A more efficient prescription, however, is : — R . Sodii Bicarbonatis, 3 ss. Syrupi Rhei Aromat., f^ ss » Aquae Menthse Pip., q. s. ad f^ iij. M. S. — Teaspoonful every two hours. The great value of rhubarb depends upon its combined laxative and astringent action, precisely what is required in simple diarrhcea. Should the stools still fail to become less frequent and more natural in color and consistence, resort must be l60 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. made to opium and astringents. A very good formula is: — R . Tr. Opii Deod., n\vj. Bismuth. Sub-nitrat. (Squibb), ^j. Syrupi, f^ ss « Mistune Cretse, q. s. ad f^iij. M. S. — Teaspoonful every two hours. The value of calomel in certain cases where the evacua- tions obstinately remain green and acrid must not be over- looked, though the necessity for its use is rare. It must be employed cautiously and in small doses, and combined with an alkali, thus: — &. Hydrargyri Chloridi Mit, gr. j. Cretae Prseparatae, ^j. M. et ft. chart. No. xij. S. — One powder every two hours. Its good effect should be noted in twenty-four hours, then it must be discontinued, and one of the other prescriptions given. When the stools become normal, wine of pepsin must be ordered for a week or more until the digestion is put upon a sound footing. In older children the treatment is very simple. All that is required is a bland diet, perhaps a dose of castor oil, and some mild astringent mixture. For example, let the patient take for breakfast — a soft-boiled egg ; milk guarded with lime-water, and stale, dry bread; for dinner — some meat broth, free from fat ; stale, dry bread, and rice and milk pudding; and for supper — milk, and stale, dry bread. The opium and bismuth mixture already given, increased in dose proportionately to the age, is very serviceable, or a combination of aromatic syrup of rhubarb and chalk mixture may be used. As with infants, a course of wine of pepsin, or pepsin with muriatic acid, should terminate the treatment. AFFECTIONS OF THE STOMACH AND INTESTINES. l6l 5. CHRONIC INTESTINAL CATARRH- CHRONIC ENTERO-COLITIS. Chronic diarrhoea, as this condition is frequently termed, is a common and fatal disease in infants. When it occurs after the completion of the first dentition it is less dangerous to life, though it runs a protracted course and interferes greatly with nutrition. Morbid Anatomy. — As with other catarrhs, the absence of appreciable lesions is quite possible ; but usually the mucous membrane of the colon is studded with minute, dark spots — the shaven-beard appearance — which the micro- scope shows to depend upon rings of vascular injection around the orifices of the follicles. In some instances there is deep congestion, limited principally to the summits of the longitudinal plicae, while in others, ulcers are also found. These ulcers are shallow, and either elongated and narrow, when they occupy the summits of the plicae, or small and circular, when they are seated between the folds. They are best seen by looking obliquely at the surface of the gut. Together with the ulcers there are numerous pearl-like projections, surrounded by narrow rings of con- gestion. These are enlarged solitary glands, and it is to their suppuration that the round ulcers are due. The whole mucous membrane is softened and thickened, unless the disease has been of very long duration, when it becomes extremely thin. The mesenteric glands are swollen and may even be caseous. In exceptional cases, the lower por- tion of the ileum presents the same changes as the large intestine. Etiology. — Entero-colitis, or a series of attacks of simple diarrhoea, may establish chronic diarrhoea ; but the disease frequently arises insidiously from the constant action of the great exciting cause — improper food. This cause is most 11 1 62 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. operative in hand-fed infants, and at the time of weaning, but it affects nurslings who are supplied with poor breast- milk or allowed to eat bits of table food, and also older children. Exposure to wet and cold is another excitant ; so, too, are various acute diseases, notably measles, croupous pneu- monia, typhoid fever, variola and scarlet fever. The predisposing agencies are bad hygienic surround- ings, particularly over-crowding. In regard to age, the period of greatest liability as well as greatest fatality, is from birth to the end of the second year; afterward it grows less common as age advances. In our climate the greater number of cases originate in early spring and autumn, when the weather is most changeable; and late winter, when it is cold and damp. Symptoms. — The first indication of the disease is an alter- ation in the character of the stools. These assume the color and consistence of putty, and are composed of curd and farinaceous matter, with semi-solid faeces, and, at times, mucus and streaks of blood. They are voided with much pain and straining, but are little, if at all, increased in fre- quency. Their odor is offensive and sour. The face is pale and listless in expression, though the child is suffi- ciently lively, takes his food well and has no fever. These symptoms continue with trifling change for two or more months, the patient gradually becoming thinner, paler and more languid. Then for the first time diarrhoea, suffi- ciently marked to arrest the nurse's attention, sets in. The evacuations now have a putrid odor, but vary considerably in other characters from day to day. They may be thin, liquid and brownish like dirty water; or clay-colored, of the consistence of thin mud ; or watery, with particles of grass-green matter (from altered blood) ; and finally they AFFECTIONS OF THE STOMACH AND INTESTINES. 1 63 may be slimy and contain whitish masses of undigested curd or particles of other food. The number of movements varies from ten to thirty in twenty-four hours; their fre- quency depending upon the amount of food taken and, to some degree, upon the weather; being greater on moist, cold days, than on warm, dry ones. They are preceded by pain, indicated by crying or uneasy movements of the legs, and are attended with straining, sometimes sufficient to cause prolapse of the rectum. The tongue is, usually, natural, though at times the tip and edges are too vividly red and the fungiform papillae too prominent. The appetite is normal, or even increased; nevertheless wasting is continuous. The skin grows pale, dry and harsh, and assumes a peculiar earthy tinge, which is deepest over the abdomen The eyes are sunken and surrounded by dark circles; the lips are bloodless and thin; the nasal lines of Jadelot are marked, and the fontanelle is depressed. The abdomen may be soft and flaccid, but oftener is distended with flatus, and then is the seat of pain, manifested by moaning and twitching of the corners of the mouth. Palpation is painless unless there be ulceration ; in the latter case there is tenderness, and the contact of the hand causes borborygmus. The skin on the internal as- pect of the thighs and the nates is reddened by intertrigo, due to the irritant action of the fasces and urine. Prostra- tion is so great that the child lies perfectly passive ; the pulse is feeble and frequent; the temperature is not ele- vated, but, on the contrary, the hands and feet often feel cold, and have a bluish color. The urine is diminished in quantity and retained for long periods. With occasional brief intervals of improvement the con- dition gradually grows worse. The stools become more 164 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. watery; look like chopped spinach floating in brown, putrid water, and may contain mucus and pus with blood, in brownish-yellow masses. Abdominal distension, tenderness and gurgling, the signs of intestinal ulceration, are present. The appetite is capricious or lost. The face becomes thin and pinched ; the forehead is wrinkled ; the hair dry and lustreless, and the whole expression that of a puny, weak, old man. General wasting progresses until the body seems to consist of little more than the bones, which stand out prominently with the muddy, harsh, flaccid skin hanging from them in folds. To this emaciation the distended belly stands in marked contrast. The fontanelle, at this stage, is deeply depressed; the pulse feeble; the breathing superficial, and the temperature sub-normal, being sometimes as low as 97.5 ° F. in the rectum. As the end approaches, the nasal lines increase in depth ; the lips are red, fissured and encrusted with scales ; the tongue dry, red and rasp-like from enlarged fungiform papillae, and the whole oral mucous membrane is covered with aphthae or thrush patches. A fetid odor hangs about the body. The feet and hands are cold, purple and cedematous. The little sufferer lies quiet, with half-shut, lustreless eyes ; from time to time an expression of pain flits over his face, but he is too weak to cry. Finally, there is no evidence of living, save the slow rise and fall of the chest as the breath comes and goes, and gradually this ceases, so gently that it is difficult to decide upon the exact moment at which life passes away. It is not uncommon for the discharges from the bowels to stop entirely for several days before the fatal termination. This circumstance alone has no favorable significance. Death may result from exhaustion, or several complica- tions may arise and hasten this event. These are serous AFFECTIONS OF THE STOMACH AND INTESTINES. 1 65 effusions, hypostatic pneumonia, exanthemata, convulsions, and thrombosis of the central sinuses. Serous effusion may take place into the pleurae, perito- neum and pericardium, but usually occurs in the form of oedema of the feet, hands, and, at times, the face. It is due to the impoverished condition of the blood and want of tonicity in the vascular walls. Hypostatic pneumonia, due to the constant dorsal decu- bitus, is a common cause of death. The exanthemata are very prone to attack the subjects of chronic diarrhoea, probably on account of the attendant prostration reducing the power of resisting contagion. Convulsions are only dangerous in the early stages of the attack; later, the nervous irritability is so blunted that this complication is rare. Thrombosis of the sinuses of the brain depends upon the withdrawal of the liquid elements from the blood by the diarrhoea. Water is then absorbed from the brain, lessening its bulk. The resulting vacuum, together with atmospheric pressure from without, leads to depression of the fontanelle, and even overlapping of the cranial bones in young subjects. If this be insufficient to compensate, the cerebral sinuses and blood vessels become engorged with blood, and as the naturally sluggish current in the sinuses is rendered more slow by inspissation of the blood and feebleness of the heart, the conditions for clotting are most favorable. At the autopsy, the clot is usually found in the longitudinal sinus, completely obliterating the channel; it is laminated, whitish, and adherent to the walls of the sinus, which are free from signs of inflammation. The veins that enter the sinus are distended with blood. The symptoms preceding death from this complication are difficult respiration ; stupor ; dilatation of the pupils and strabismus; spasm of the poste- 1 66 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. rior cervical muscles; fulness of the jugular veins, and uni- lateral facial paralysis. When the case tends to recovery, the evacuations become more solid and natural in odor and color; the latter change being caused by the reappearance of bile. The semi-stupor disappears, and the child grows very irritable, often crying out and shedding tears — a most favorable omen. The flesh, also, begins to return, the buttocks being the first part of the body to show the improvement. Diarrhoea is, after a time, succeeded by a constipated condition of the bowels. Convalescence is protracted. Children over two years of age, when affected with chronic diarrhoea, are pale, thin, languid and readily fatigued. Irri- tability of temper, night terrors, and nocturnal incontinence of urine are common. The tongue is red at the tip and edges, with prominent papillae, and perhaps light frosting. The appetite may be normal, craving, or capricious. The stools vary in number from three to twelve in twenty- four hours; in the former case they are semi-solid, light colored, and mixed with minute masses of green or color- less mucus ; in the latter, they consist of dark liquid, containing lumps of clay-colored faeces; this variation bears some relation to the state of the weather. The evacuations are always fetid in odor, and the act of defecation is attended by pain and straining. The abdomen is distended by flatus. Feebleness of the pulse is proportionate to the general weakness ; respiration is unaltered, and there is no pyrexia. In some instances the stools are limited to four or five a day, and are composed of almost completely undigested food and mucus. One evacuation occurs in the morning, soon after rising ; the others during or immediately after meals. They are preceded by griping pain and by so urgent a desire, that the patient has difficulty in waiting for the AFFECTIONS OF THE STOMACH AND INTESTINES. 1 67 chamber or reaching the closet. The condition undoubtedly depends upon great irritability of the intestine and exagger- ated peristalsis. Diagnosis. — The diarrhoea of chronic catarrh is to be distinguished from that of tuberculosis of the intestines ; the only condition with which it is likely to be confounded. Should it begin soon after birth or at weaning ; if there be a history of bad feeding or exposure, and if there be no constant elevation of temperature, the affection is probably catarrhal. A temporary rise in temperature may be caused by the eruption of teeth or other passing irritation, and is of no diagnostic importance. Tuberculous diarrhoea, on the contrary, occurs after the third year, and is attended by pyrexia and enlargement of the mesenteric glands. On pressure there is tenderness and gurgling in the right iliac fossa, and tension of the abdomi- nal wall over this region. There is also evidence of tuber- culosis of the lungs. The evacuations, too, are distinctive ; they are intensely fetid, brown and liquid, when passed, but, on standing, deposit a dark sediment, composed of flocculent matter, with small, black clots of blood, and little masses of mucus, and pus. The presence, therefore, of these features or their absence, while the symptoms of catarrhal diarrhoea are observed, will determine the nature of the affection in children who have passed the age of infancy. Prognosis. — Chronic intestinal catarrh is fraught with great danger when it attacks children under the age of two years. It is particularly fatal when it follows an acute dis- ease; when it occurs in syphilitic, rachitic or feeble subjects, and when it is complicated by measles or other exanthem. Unfavorable symptoms are dryness and roughness of the tongue ; thrush ; anasarca ; features indicating intestinal 1 68 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. ulceration, great depression of the fontanelle, and extreme emaciation. Favorable symptoms are normal progression of dentition ; the reappearance of tears ; intermissions in the diarrhoea, and improvement in the character of the stools and general symptoms. Treatment. — As the disease is produced by over-crowd- ing, neglect, exposure and unsuitable food, the initial measures of treatment must be the regulation of the hy- giene, clothing and diet. The sleeping-room must be kept at a uniform temperature — between 68° and yo° F. — it must be dry, well-ventilated, and, if possible, heated, in cold weather, by an open wood- fire, and occupied by no one but the patient and nurse. During the day the patient must be moved to another room, being wrapped in a blanket if cold halls have to be passed. This room should be large, well-ventilated, dry, and kept at the same temperature as the first. After the removal, the windows of the sleeping-room should be opened, and the bed and its linen thoroughly aired and freshened. Soiled diapers or chambers containing stools are to be removed at once, and no cooking is to be done in either room. The child's person must be kept clean, and it is especially important to sponge the perineum and nates with warm water after each movement of the bowels ; and, if there be any redness of the skin, to anoint the parts with oxide of zinc ointment, or powder them. It may be impossible to carry out this plan among poor pa- tients, but it can be approximated by keeping the baby clean ; out of the kitchen and away from the door-step. As to clothing, the body must be clad in woolen from the neck to the toes, and, as an additional protection, a broad flannel, abdominal belt must be worn. So clothed, the patient may be taken into the open air on dry days, AFFECTIONS OF THE STOMACH AND INTESTINES. 1 69 during the early stages of the attack. Soiled garments are to be replaced at once by fresh ones, and diapers must be washed when soiled ; not simply dried and used over again. The diet should vary with the age of the patient. The great principle being to maintain the general nutrition with the least amount of irritation of the intestinal mucous membrane. Infants partly nursed and partly bottle-fed do best when restricted to the breast, provided the latter be healthy. If the diarrhoea do not improve under the change, both the intervals and the time of nursing must be shortened. If the infant be hand-fed, every caution must be taken to insure purity of the food and perfect cleanliness of the feeding apparatus. The latter must consist of a simple bottle and tip, unless the amount to be given be very small, when a teaspoon can be used. The quantity of food and intervals of feeding always depend upon the degree of diarrhoea ; thus, in very severe cases, not more than a tea- spoonful every fifteen minutes can be allowed. The quality depends upon the age. For an infant under six months, cow's milk and lime- water, in the proportion of one part to two, or in equal quantities, may be tested. If this undergo acid fermenta- tion, fresh whey and veal or chicken broth, with equal quantities of barley-water, may be substituted. A tea- spoonful of Mellin's food, dissolved in whey, barley-water, or diluted broth, makes an admirable food. At the age of six months, a good scale of diet when milk cannot be taken is : — First meal, 7 A.M. — One teaspoonful of Mellin's food dissolved in six ounces of veal broth and barley-water, in equal parts. Second meal, 10 a.m. — One tablespoonful of cream in six ounces of freshly prepared whey. 170 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. Third meal, 1 p.m. — Same as first, with chicken broth in place of veal broth. Fourth meal, 5 p.m. — Same as second. Fifth meal, 10 p.m. — Same as first. After a week or more of improvement, milk may be re- sumed gradually, in the beginning at the first meal only; then at the first and last, and so on. Should these foods disagree, they must be discontinued and the child fed upon meat juice. This is prepared by chopping a piece of sirloin steak, free from fat or ten- don, into small bits, and, after slightly warming, pressing out the juice with a lemon-squeezer. A teaspoonful, with a little salt, is to be given four times a day, and the quantity gradually increased as the peculiar fetid odor which it im- parts to the stools disappears. After the age of six months, the yolk of a raw egg, well beaten with ten drops of brandy, a teaspoonful of cinnamon water, and a little white sugar, may be administered once or twice a day, together with the milk, whey, or broth-food. After twelve months, if milk can be taken, the following diet is suitable : — First meal, 7 a.m. — Two teaspoonfuls of Mellin's food dissolved in six ounces of milk and barley-water, equal parts. Second meal, 10 a.m. — Four ounces of veal broth with two ounces of barley-water. Third meal, 2 p.m. — The yolk of a raw egg, beaten up well with twenty drops of brandy, a teaspoonful of cinnamon water and a little white sugar. Fourth meal, 6 p.m. — Same as second, or four ounces of fresh whey with a tablespoonful of cream. Fifth meal, 10 p.m. — Same as first. It is most important to remember that if the evacuations AFFECTIONS OF THE STOMACH AND INTESTINES. I7I be very frequent and watery, there can be no set meals, but the food must be given by the teaspoonful at intervals of ten or fifteen minutes. Also, that between set meals and these minimum quantities, there is a wide range in the amounts and intervals, according to the grade of the symp- toms. From older children it is necessary to withhold potatoes and farinaceous vegetables generally; fruits, sugar, sweet- meats, pastry, hot bread or cakes, butter and all made and highly-seasoned dishes ; at the same time the bulk of each meal must be somewhat restricted. A good diet is : — For * breakfast, at 7.30 a.m. — One or two tumblerfuls of milk warmed and diluted by the addition of a fourth part of hot water ; the yolk of a soft-boiled egg, salted, and a slice of thin, dry toast. For luncheon, at 1 2 m. — The soft parts of eight raw oys- ters, flavored by lemon juice, and a Boston cracker. Or in summer a small teacupful of junket, with a cracker. For dinner, at 3 p.m. — A bit of the breast of chicken cut up very fine, or a tender piece of roast beef or beef-steak treated in the same way ; with a tablespoonful of well- boiled spinach, asparagus tops, cauliflower tops, or stewed celery, and a thin slice of dry, stale bread. For supper, at 7 p.m. — A glass of milk, warmed as at breakfast, and a slice of well-made cream toast. An important rule in all cases is to watch the diet care- fully until all danger of a relapse has passed. Baths and external applications are useful. Infants who are not much prostrated should be placed in a hot bath (95°-ioo° F.) every evening for three minutes, then quickly dried, anointed over the whole body with warm olive oil, wrapped in a blanket and put to bed. If there be much prostration, the bath must contain mustard, one teaspoonful 172 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. to the gallon, and the child kept in until the supporting arms of the nurse begin to tingle. When intestinal ulceration is suspected, the belly should be enveloped in a light flax-seed poultice, or, what answers as well, a layer of carded cotton covered with oiled silk. Medicines are to be selected according to the stage of the attack. Early, while the stools are little increased in num- ber, but putty-like and of sour odor, the bowels must be gently acted on by: — R. Pulv. Rhei, gr. vj. Sodii Bicarbonatis, gr. xij. M. et ft. chart. No. vj. S. — One powder three times daily, for an infant of three to six months. Afterwards — on the succeeding day, usually — the follow- ing powder may be administered : — R. Pulv. Ipecacuanhas Comp., gr. iv. Cretae Praeparatse, gr. xxxvj. M. et ft. chart. No. xij. S. — One powder every four hours. Or often better: — R. Tr. Opii Deod., ti\,vj. Sodii Bicarb., gr. xlviij. Syrupi, f^ss. Aquae Mentha? Pip., q. s. adf5iij. M. S. — One teaspoonful every four hours. When the stools become frequent and green, the mixture of opium, bismuth and chalk, already given (page 160), is very useful ; and if tenesmus be very severe, a sedative enema must be used, as: — R . Tr. Opii, gtt. iij. Potass. Bicarb., gr. iij. Mucilag. Amyli., f^ ss - M. S. — To be injected into rectum. AFFECTIONS OF THE STOMACH AND INTESTINES. 1 73 This may be repeated every six or twelve hours, accord- ing to the necessity, taking care that the child — and all children are very susceptible — does not get too much opium. Should the diarrhoea still continue, and the stools be- come watery and very fetid, astringents are required; for example : — R . Acid. Sulphurici Aromat, Tt\,xxiv. Liquor. Morphiae Sulph., f^ij- Elix. Curagoae, f J ss. Aquae, q. s. ad fjiij. M. S. — One teaspoonful every three hours. Or— R . Argenti Nitratis, gr.ss. Syr. Acaciae, f|> ss - Aquae, q. s. ad f^iij. M. S. — One teaspoonful every three hours, midway between meals, if possible. Nitrate of silver is most valuable when the stools contain mucus and blood, and aphthae or thrush are present. It may be also used as an injection, if there be evidences of ulceration, thus: — R. Argenti Nitratis, gr. j. A q U3e » f 3J- M. S. — Inject once or twice daily after cleaning out the rectum with an injection of warm water. These injections must be suspended for twenty-four hours after being continued for three days. Prostration and depression of the fontanelle demand stimulants, Ten drops of whiskey in water every two hours is about the average dose, but it may be given oftener and in larger quantities as circumstances require. 174 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. As soon as the stools become normal in character and frequency, the child must be ordered tonics, as : — i& . Liquor. Ferri Nitratis, TT^xxiv. Glycerinae, fijss. Aq. Menthae Pip., q. s. ad f^iij. M. S. — One teaspoonful three times daily. Or— R. Ferri et Ammonii Citratis, gr. xij. Tr. Gentianae Comp., f £j. Spt. Lavandulae Comp., f ^ ij. Syrupi Limonis, q. s. adf^iij. M. S. — One teaspoonful three times daily. For the constipation of convalescence very small doses of castor oil — twenty drops — may be ordered once or twice daily, but it is best not to interfere unless the bowels have been indolent for twenty-four or forty-eight hours. With older children the medical treatment is more simple. Ordinarily, either of the following prescriptions will suffice : — &. Syr. Rhei Aromat., f ^ vj. Sodii Bicarbonatis, gij. Tr. Opii Deod., . . . . ■ TTLxxxvj. Aq. Menthae Pip., q. s. adf^iij. M. S. — One teaspoonful every three hours, for a child from four to six years. Or if the diarrhcea resist : — 1£. Tr. Krameriae, f ^ iij. Tr. Opii Camphoratae, f ^ ij. Spt. Lavandulae Comp., f 3 ij. Misturae Cretae, q. s. ad f^ iij. M. S. — Two teaspoonfuls every three hours. The lienteric form of diarrhcea should not be treated by astringents but by nux vomica, followed by arsenic. For AFFECTIONS OF THE STOMACH AND INTESTINES. 1 75 instance, until the stools become less frequent and urgent and the griping pain diminishes, a good prescription is : — R . Tr. Opii Deod., Tr. Nucis Vomicae, aa TT\xlviij. Aq. Menthae Pip., q. s. adf^iij. M. S. — One teaspoonful before each meal, at the age of six years. Afterwards : — R. Liq. Potassii Arsenitis, f ( ^j. Inf. Gentianae Comp., q. s. ad f 5iij. M. S. — One teaspoonful after each meal. During convalescence from chronic diarrhoea, older chil- dren do well upon the same tonics as infants, the doses being proportionately increased. 6. ENTERO-COLITIS. Entero-colitis, or inflammatory diarrhoea, is the scourge of our large cities during the summer months, when it brings death to hundreds of children, especially among the over-crowded, ill-fed poor. To it is due the popular dread of that period of an infant's life termed " the second sum- mer," and justly, for among those unfortunates who are obliged to pass this time in crowded houses, and narrow, filthy streets, the instances of complete escape are very rare. Morbid Anatomy. — The anatomical lesions consist in inflammatory hyperaemia of the intestinal mucous mem- brane. This may be distributed over the whole tract, but commonly it is limited to the ileum and colon, and is most intense in the neighborhood of the ileo-csecal valve and the sigmoid flexure. The mucous membrane is reddened, I76 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. swollen and softened. Redness is either general or in the form of arborescent patches about the follicles ; while swelling and softening are proportionate to the degree of congestion. The former is sometimes so great at the lower end of the ileum as almost to occlude the valve ; to this has been attributed the vomiting which, in the absence of gastric lesions, is otherwise difficult to explain. The isolated glands are enlarged, and more opaque than normal, having the appearance of grains of white sand scattered over the mucous surface, and the Peyer's patches are tumefied and projecting, with punctated surfaces. On the peritoneal aspect, the gut, in positions corresponding to the inflamed glands, presents areas of arborescent injection. There is moderate enlargement of the mesenteric glands. Front this condition it is but a step to the state of ulcera- tion seen in chronic intestinal catarrh — a not infrequent result of entero-colitis. The stomach, as already hinted, is usually normal in appearance ; occasionally its mucous membrane is reddened and thickened, and it is quite possible that this viscus is often the seat of a catarrh so moderate in degree as to leave no evidences after death, though sufficient to give rise to vomiting during life. Etiology. — Season, age and locality of residence are important factors in the causation. Only isolated cases occur in the winter months, and these are met with among the poor, with whom it is a habit, for convenience in watch- ing, to keep infants in the living room, which is also the kitchen ; this is heated by the cooking-stove, and is either intensely hot when the room-door is closed, or too cold when it is left open, in the frequent excursions of the older members of the family to the yard or street. There is, therefore, a constant exposure to sudden and marked AFFECTIONS OF THE STOMACH AND INTESTINES. \JJ changes in temperature. At the same time the air of such a room is contaminated by cooking, by re-breathing, and by the exhalations from soiled clothing and dirty bodies. Two sufficient causes for an attack of entero-colitis. About the middle of May or June, according to the character of the individual season, cases become more common, and as the summer heats are established, in July, August, and the first half of September, the number is augmented to the propor- tions of an epidemic. Late in September or in October, ac- cording, again, to the season, there is a marked diminution, and this increases as winter approaches. During the summer the number of cases and deaths, varies with the range of the thermometer; several successive days with a tempera- ture above 90 F. being attended by a great increase, while a similar period with a temperature below 8o° is followed by a decided decrease. Hot, damp weather is the most pro- ductive, and of all months August is the most fatal, both on this account and because a high temperature is maintained during the night. Infants between the ages of six and eighteen months are by far the commonest sufferers. Their liability depends upon the sympathetic irritation of the alimentary tract attending the cutting of the teeth ; the increased tendency to inflammation produced by the rapid development that the intestinal glands and follicles are simultaneously under- going, and the fact that weaning, with its consequent change of diet, usually takes place during this interval. From the eighteenth month to the end of the second year, about one- fourth as many cases occur, and the third period of greatest frequency is from birth to the sixth month. Children over three years are not often attacked. Residence in large cities is almost an essential etiologi- cal condition ; the vast majority of cases occur where the 12 I78 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. streets are narrow and more than ordinarily filthy, and where the houses are overcrowded and dirty, and the people poor, ill-fed and unclean. There must be another factor at work here besides the elevated temperature, since in the open country immediately surrounding affected cities, where the thermometer ranges nearly as high, the disease is of excep- tional occurrence. This factor is an atmosphere polluted by poisonous gases and containing countless bacteria, the result of decomposing organic substances. Another potent agent is bad food. Infants, hand-fed from birth, are the most frequent sufferers ; next, those who are weaned early; in both, the chief injurious articles of diet are sour milk, farinaceous preparations in excess, and "tastes" of table-food. Nursing infants are more exempt, but even with them, too frequent and continuous feeding, or breast-milk of abnormal quality, when other conditions are unfavorable, often produces entero-colitis. Symptoms. — For one or two days prior to the actual attack, the infant is restless and fretful ; his sleep is dis- turbed by moaning or fits of crying ; he is paler than usual, and his head and, perhaps, the palms of his hands, feel hot. He also ceases to empty his bottles; after feeding, eructa- tions of very sour-smelling material are apt to occur, and the stools are somewhat more numerous and softer than usual. Next, vomiting and diarrhoea set it. The former occurs after feeding, and, in bad cases, is so obstinate that nothing is retained. The matter rejected consists of sour, acid and curdled milk, or other food imperfectly digested. The stools range from six to twenty or more in twenty- four hours, and vary in character from day to day, and even from hour to hour. At first, they are semi-solid, homogeneous, yellow in color and neutral in reaction ; then AFFECTIONS OF THE STOMACH AND INTESTINES. 1 79 they become more liquid and green, though still homoge- neous and neutral, and then the reaction becomes acid without change in the other characters. Often they are semi-fluid, heterogeneous, green with little masses of yel- low faeces, and neutral ; or semi-fluid, heterogeneous and green, with fragments of yellowish-white caseine and acid ; or watery, with floating flakes of white, yellow or green matter, and acid. Mucus and blood may be mixed with any of these stools ; the first in stringy masses ; the sec- ond, in bright red streaks or merely tingeing the mucus. In severe cases the passages become watery and so colorless as hardly to stain the diapers. The odor at first is faecal, then sour, and finally offensive. The act of defecation is preceded by pain, manifested by the expression of the face, by crying, and by twisting of the trunk and drawing up of the legs. Sometimes there is tenesmus and slight prolapse of the rectum ; it is under these circumstances that blood appears in the stools. The tongue is dry, red at the tip and edges and covered in the centre with a light white coating ; the appetite is diminished and the thirst increased. The abdomen is dis- tended by flatus, and, at times, there is tenderness on pres- sure. With these features there is pyrexia, moderately high and continuous for the first three or four days, afterward remittent ; the head is especially hot, and the palms of the hands are dry and burning to the touch. The pulse is weak and frequent, beating 120, or even 140 times per minute. The urine is reduced in quantity and passed at long intervals, sometimes only two or three times a day. As the diarrhoea continues the face becomes pale ; the eyes are surrounded by dark circles ; the nasal lines appear ; the fontanelle, if still membranous, is depressed; the fat l80 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. disappears from the body ; the muscles grow soft and flabby ; the buttocks and inner surfaces of the thighs are reddened by the acid stools and concentrated urine, and there is great feebleness and languor. In grave attacks these changes take place in an incredibly short space of time, twenty-four hours being ample to reduce an active, robust infant to a mere shadow of himself. If death approach, the patient, in some cases, grows fretful; has a dry, burning skin ; rolls the head from side to side ; vomits incessantly ; has strabismus and indolent pupils, and may have convulsions, which are more frequently uni- lateral than general. In others, there is drowsiness, an apathetic refusal of food, cessation of vomiting and diar- rhoea, and coolness of the extremities. This difference depends upon the acuteness of the attack, for upon this rests the preservation or loss of nervous irritability. The great diminution of the urinary excretion suggests the possibility of the fatal termination being, in some in- stances, due to uraemic poisoning. When the attack tends to recovery the vomiting stops ; the motions are less numerous and more faecal ; the skin becomes cooler and more moist; the urine is excreted freely ; the eyes grow bright ; the child again shows inter- est in his surroundings ; takes his food better, and rapidly regains flesh and strength. Diagnosis. — The pyrexia, the vomiting, and the fre- quency and character of the stools, taken in conjunction with the early age of the patient; the season and local- ity of occurrence; and the almost epidemic prevalence of the disease, make its distinction an easy matter. The portion of the intestinal canal chiefly involved is not so readily determined, though the presence of mucus and blood in the evacuations points to the colon as the seat of AFFECTIONS OF THE STOMACH AND INTESTINES. 161 inflammation ; their absence, by inference, to the small intestine. Prognosis. — Inflammatory diarrhoea ranks among the most dangerous of the affections of infancy, both from its inherent nature and its tendency to run into chronic entero- colitis. Nevertheless, under appropriate management, a large proportion of cases recover. The outlook is most dis- couraging when the infant's lot has been cast in poverty ; when it has been hand-fed from, or soon after, birth ; and when it has had the bad fortune to be born in the late winter or spring, so that weaning and the time of cutting the more troublesome teeth come together in the second summer. The unfavorable features are high fever, very frequent and watery evacuations, rapid collapse, cerebral symptoms and convulsions. An attack may prove fatal in four or five days, or it may be protracted for two weeks. The latter is about the dura- tion of severe cases that terminate in recovery. One attack predisposes to another, an important point to remember in the treatment by change of climate. Treatment. — People with means avoid the dangers of summer diarrhoea by taking their children to the country, sea-shore or mountains, where the air is uncontaminated, the heat less intense and the milk pure. Such escape is not open to the children of the poor ; nevertheless, much may be done to preserve their health by keeping them dur- ing the day in the fresh air of public parks ; by bathing in cool water; by proper, cleanly clothing; good food — for good milk is as cheap as bad — and by attention to the cleanliness of beds and sleeping rooms. This the parents can, and in many cases will do, and if they would only secure well-paved and decently clean streets — for it is impos- 152 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. sible to clean ill-paved ones — entero-colitis would become a far less common disease. When an attack occurs during the hot months, the pa- tient, if possible, must be sent at once from the city to the sea-side or country. The locality selected should be near at hand, or the journey will be too fatiguing ; still, it is im- portant to fix upon a place affording a decided change of air and a lower temperature. From Philadelphia the infant may be taken to Cape May, Point Pleasant, Long Branch or any of the many resorts on the Jersey coast, kept there for two or three weeks and then removed to the New Hampshire hills for the remainder of the summer. A long stay is essential, since a return to town in hot weather is almost certain to be followed by a relapse. If circumstances render it impossible to carry out this most potent of all prescriptions, fresh air must be secured by taking the child to the public squares in the cool of the morning and evening, or by spending the day in the Park, or, better still, by a morning and evening trip on one of the river steamboats. The heat of the day must be spent in as cool a room as can be had. It is of great moment to let the little sufferer rest in bed and not on the hot lap or shoulder, and when out, to wheel him in a coach rather than carry him. Many a stout mother has hastened her infant's death by too fond and constant nursing. The clothing must be as thin as possible, provided, always, that woolen be worn next the skin. Twice or three times a day, in very hot weather, the whole surface of the body should be sponged with water at a temperature of 8o° F., and dried with gentle rubbing. The bracing effect of these baths is greatly increased by the addition of rock salt or concentrated sea-water, if the AFFECTIONS OF THE STOMACH AND INTESTINES. 1 83 purse can afford it. These cool spongings must be sup- planted by full warm baths when there is much prostration. In regulating the diet, it must be remembered that the presence of fever, with increased thirst, leads the child to take more liquid food than is needed or can be digested ; consequently, it is necessary to specify the quantity as well as the quality of the food. Infants at the breast are to he suckled only at intervals of two or three hours, according to their age, and taken away before they have completely satisfied themselves. Hand-fed babies are to be similarly restricted. As cows' milk must constitute the bulk of their food, it is important to see that it is obtained fresh every day from a reliable dealer ; received and kept in perfectly clean vessels, and administered from an absolutely clean bottle fitted with a simple tip. In very hot weather, and in houses where ice is scarce, it is well to have the whole day's supply boiled for five minutes as soon as it comes in the morning, to pre- vent its souring. From this a portion is to be taken at each time of feeding and prepared in one of the following ways : — Milk, fgiij. Cream, f^ss. Lime-water, f^ijss. Sugar of milk, gj. Mix in a clean tin-cup, pour into bottle, adjust tip, and warm by plunging into hot water. Milk, fgiij. Cream, f^ss. Mellin's Food, gij. Hot water, f^ijss. Dissolve the Mellin's food in the hot water, add the milk and cream, and, if necessary, warm as before. 184 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. Milk, fjfiij. Cream, f^ ss - Flour-ball,* ^j. Water, f" ^ ijss. Either one of these foods may be given every three hours to a child of ten or twelve months old. The quantity is less and the dilution greater than for a healthy infant of the same age, because enfeebled digestion demands a propor- tionate reduction in the amount and strength of the food. When preparations of milk are vomited or passed undi- gested from the bowels, a whey mixture or strippings can be resorted to, and if these fail, beef-juice, or — Flour-ball, £ij. Water, fgvj. Mix, and add — Half the white of a fresh egg. Bits of ice and cool, filtered water can be allowed, in moderation, to relieve the thirst. The medical treatment, should the case be seen early, may be initiated by a laxative. A teaspoonful of castor oil with five drops of paregoric, or the same quantity of spiced syrup of rhubarb, will be sufficient for an infant of one year. Afterward, while the stools are yellow, homogeneous and not very frequent, alkalies and astringents are alone needed, as : — R. Sodii Bicarbonatis, gr. xviij. Bismuthi Sub-carbonatis (Squibb), .... gr. xxxvj. Pulv. Aromat., gr. yj. M. et ft. chart. No. xij. S. — One powder every two hours, for a child of one year. Or— R. Sodii Bicarb., gr. xxxvj. Syrupi Rhei Aromat., f :f ss. Misturse Cretse, q. s. ad f ^ iij. M. S. — One teaspoonful every two hours, at the same age. * For mode of preparing Flour-ball and mixing with water, see Part III. AFFECTIONS OF THE STOMACH AND INTESTINES. 1 85 When the stools are green, numerous, and acid in reac- tion, the indication for alkalies is still stronger, but small doses of opium should be added, thus : — R . Tr. Opii Deod., rr^vj. Bismuthi Sub-carb., gr. lxxij. Syrupi, f^ ss. Misturse Cretse, q. s. adf^iij. M. S. — One teaspoonful every two hours. R. Pulv. Ipecac. Comp., gr. ij . Bismuthi Sub-carb., gr. xxxvj. M. et ft. chart. No. xij. S. — One powder every two hours. Another good mixture, when there is much pain and heat of skin, is : — R. Magnesii Sulphatis, £j. Tr. Opii Deod., rt\vj. Syrupi, fgj. Aq. Menth. Pip., q. s. ad f^iij. M. S. — One teaspoonful every two hours. At the same time, it is well, two or three times a day, to redden the skin of the whole abdomen with a weak mustard draught — one part of mustard to five of flour. When the evacuations are liquid and contain whitish or greenish flakes, the opium and alkaline treatment should be resorted to first; but if, after a fair trial, their char- acter remain unchanged, good results will often be ob- tained by minute doses of calomel, continued from twelve to forty-eight hours, as in the following prescription : — R. Pulv. Ipecac. Comp., gr. ij. Hydrarg. Chlorid. Mit., gr. j. Cretae Praeparatae, gr. xxxvj. M. et ft. chart. No. xij. S. — One powder every two hours, or every four hours alter- nating with the opium and bismuth mixture. 1 86 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. Under the mercurial the stools become homogeneous and yellow, and the irritability of the stomach is much relieved. If, however, this change is not observed after a forty-eight hours' course, it is useless to push the treat- ment further. Very frequent and serous stools demand more powerful astringents, as : — &. Acid. Sulph. Aromat., Tt^xxiv. Liquor. Morphiae Sulph., f^j. Elix. Curacoae, f.^ij- Aquae, q. s. ad f^iij. M. S. — One teaspoonful, diluted, every two hours. Or— R . Argenti Nitratis, gr. ss. Syrupi Acacias, f^ ss « Aquae, q. s. ad f 3; iij. M. S. — One teaspoonful every two hours. Rectal injections are very useful, and sometimes, when the stomach is very irritable, may be the only means of medication. Laudanum, in doses of three drops in a table- spoonful of starch-water, may be given every six hours, or oftener, when the motions are frequent and attended by pain and straining; nitrate of silver when they are serous, or contain mucus, blood or pus. J. Lewis Smith's formula is a good one ; it is : — &. Argenti Nitratis, gr. j. Bismuthi Sub-nitratis, gj. Mucilag. Acacia?, Aquae, aa ^ ss. M. The whole of this is to be used at once, with or without the addition of laudanum, and it may be repeated at inter- vals of twelve hours. These injections must be preceded by enemata of warm water to clean out the bowel, and they AFFECTIONS OF THE STOMACH AND INTESTINES. 1 87 must be discontinued for twenty-four hours every third or fourth day. When the buttocks and thighs become excoriated, the parts must be kept dry and clean, and protected by frequent applications of oxide of zinc ointment. Stimulants are required when there is prostration or col- lapse. Wine of pepsin is to be preferred on account of its com- bined stimulating and digesting qualities, but whiskey or good brandy, if it be possible to get it, can be used. The dose must depend entirely upon the age and the depression to be resisted. In cases of recovery, the diet and hygiene must be care- fully watched until all danger of a return has passed ; the astringents are to be gradually dropped, and digestants and tonics ordered. Of the former, a powder composed as fol- lows may be given : — R . Pepsin. Sac, Sodii Bicarb., aa gr. xxx. Pulv. Aromat., gr. vj. M. et ft. chart. No. xij. S. — One powder four times daily. Or pepsin may be combined with muriatic acid, thus : — &. Pepsin. Sac, %). Acid. Muriat. dil., f gj. Aq. Cinnamoni, q. s. ad f 3 ii j . M. S. — One teaspoonful, diluted, three times daily. Tonics should not be ordered until the digestion has been righted ; then simple bitters, as tincture of nux and compound tincture of gentian, are to be given, and afterward the citrate of iron and quinia, ferrated elixir of cinchona, or bitter wine of iron. The exceptional cases that occur in cold weather should, of course, be treated at home in a well-ventilated and warm 1 88 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. room; otherwise, the only alteration to be made in the general plan of management is to envelop the abdomen with light linseed poultices, or with cotton covered by oiled silk. 7. CHOLERA INFANTUM. This affection occurs in teething children during hot weather, and is characterized by a sudden onset, high fever, irritability of the stomach, frequent serous evacuations, changes in the respiration and pulse, and rapid collapse. It is a far less common disease than entero-colitis, and is the analogue of cholera morbus in the adult. Morbid Anatomy. — In cases that run the ordinary course and die early, the gastro-intestinal mucous mem- brane is congested, thickened and softened, and the fol- licles and Peyer's patches are enlarged. In other words, the appearances indicate the early stage of inflammation, which passes into lesions identical with those of entero- colitis, when the patient, as sometimes happens, survives the choleraic stage and dies, subsequently, from a more protracted diarrhoea. But, in addition to inflammation, there is probably some envolvement of the sympathetic nerves, leading to dilatation of the capillaries and transu- dation of serum into the intestine, and to alterations in the pulse,, temperature, respiration and urinary excretion. The nature of this is paralytic, so far as the intestine is concerned, and resembles in its results experimental section of the sympathetic nerves. It is due, in part, to direct over-stimu- lation by the irritant contents of the canal, and in part to the nerve exhaustion produced by high atmospheric tem- perature, one of the essential causes of cholera infantum. The changes in calorification and in the functions of the AFFECTIONS OF THE STOMACH AND INTESTINES. 1 89 heart, lungs, and kidneys depend upon reflected irritation, and also, perhaps, upon the depressing effects of heat on the governing nerve centres. Etiology. — Like entero-colitis, this is a disease of cities, finding its victims chiefly among those who live in pov- erty and squalor. Almost exclusively confined to hot weather, it may occur at any time between the middle of May and the end of September, though the greater propor- tion of cases originate during the latter half of July, August, and the first half of September. Infants from six to twelve months are the most susceptible subjects ; it may, however, occur at any age up to two years. The susceptibility of the former age is due to the great functional activity of the intestinal mucous membrane and the rapid development of the follicles that accompany dentition rather than the mere act of cutting teeth. The direct causes are high temperature (85°-95° F. or more); sustained for several days, and espe- cially if associated with a moist atmosphere, exposure to an atmosphere rendered impure by noxious gases and bacilli generated from filth by heat, impure water and bad food. Symptoms. — An attack may arise in the midst of health, or it may be preceded by diarrhcea. In either case the onset is sudden. The infant begins to void copious stools. These at first, if there has been no premonitory diarrhcea, contain more or less faecal matter, but they soon become watery. Sometimes they are so serous as to soak away into the diaper without leaving any stain ; at others, they contain a few yellow or green flocculi or little masses of mucus, and, in both instances, are odorless. Again, they are composed of yellow or brown liquid, containing a small proportion of thin, faecal matter, and have a peculiar musty and offensive odor, which clings to the napkins and clothing, and even I9O DISEASES OF DIGESTIVE ORGANS IX CHILDREN. to the body of the child, in spite of the utmost efforts at cleanliness. The number varies from eight to thirty in twenty-four hours, and they are evacuated with considera- ble force. At the same time, or soon after, the stomach becomes so irritable that everything, even to a mouthful of ice-water, is rejected as soon as swallowed, and there is violent retch- ing. Appetite is lost, but there is intense thirst, the patient eagerly drinking when the opportunity offers, and following the glass, as it is removed, with greedy eyes. The tongue, originally moist and lightly frosted, soon becomes dry and pasty, and protrudes from the parched lips. The abdomen is flaccid and indolent. There is great restlessness ; the temperature is elevated to 105 ° or even 108 F.; the pulse is small and very frequent, counting from 130 to 150 beats per minute ; the breathing becomes irregular and anxious, and the urine is greatly diminished in quantity. With these symptoms there is a marked and appalling change in appearance. Within a few hours, the infant, per- haps plump and rosy before, can scarcely be recognized ; the face becomes pale and pinched ; the eyes and cheeks sunken, and the eye-lids and lips permanently parted from loss of muscular contractility ; the fat melts from the body ; the muscles grow flabby ; the bones appear prominent, and the skin, often greenish or cadaverous in hue, hangs in loose folds. Soon the features of collapse appear. The hands, feet, nose, and even the breath, become cool, the pulse is thready and so frequent as to be uncountable ; the respira- tory movements are more unequal, and there is drowsiness, apathy, and suppression of urine. As life ebbs away, the vomiting stops; the surface becomes cold and clammy ; the AFFECTIONS OF THE STOMACH AND INTESTINES. I9I face is set with the lines of death ; the respiration is quickened and shallow ; the pulse scarcely perceptible, and the patient sinks into a state of semi-coma, with bleared eyes and contracted pupils. In this condition the end may come quietly or be preceded by slight con- vulsions. The course of the disease, whatever the result, is al- ways very short. It may prove fatal in from one to four days, or the character of the attack may change and death result later from a secondary inflammatory diar- rhoea. In case of recovery, the stools, after four or five days, gradually become less copious, frequent and watery, more faecal and of better odor ; vomiting stops ; thirst diminishes ; appetite returns ; the urinary excretion is reestablished ; the temperature and pulse fall ; the respiratory movements become rhythmical ; emaciation ceases, and the child, though very feeble, again notices his surroundings, and after a week or more of simple diarrhoea, regains a mod- erate degree of health. Diagnosis. — The character of the stools; the extreme irritability of the stomach ; disturbed respiratory rhythm ; high temperature; intense thirst and rapid emaciation and collapse, distinguish this from entero-colitis, and from other forms of diarrhoea. There is a certain resemblance between cholera infantum and sunstroke, and, by some, the two conditions have been considered as identical. The points of similarity as well as those of dissimilarity, may be seen in the following table :— I92 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. CHOLERA INFANTUM. SUNSTROKE. Temperature 105 to 108 F. Temperature often 108 F. Pupils contracted. Pupils contracted. Evacuations watery. Evacuations watery. Respiration embarrassed. Respiration embarrassed. Urine scanty. Urine scanty. Cerebral symptoms marked, but Cerebral symptoms marked, but secondary. primary. Gastro-intestinal symptoms, prece- Gastro- intestinal symptoms, sec- dent and prominent. ondary. Onset rapid. Onset sudden, by a stroke. Preceded by diarrhoea or un- No such previous history, comfortable sensations. Restlessness at onset. Stupor from beginning. Occurs at any time of day or Occurs only during excessive heat night. of day. Inflammatory lesions of intestines. No such lesions. Between epidemic cholera and cholera infantum it is im- possible to make a diagnosis. Prognosis. — The prospect is most discouraging, and even in seemingly favorable instances the opinion as to the result must be guarded, for though the choleraform symp- toms be survived, there is danger from the succeeding diarrhoea. The disease is most fatal in children of the poor, who are badly fed and subjected to the worst hy- gienic influences ; conversely, it is more apt to terminate in recovery in the rich, who can be treated in large, airy rooms, fed on good food, and removed to healthy localities. Treatment. — The large and frequent watery evacuations are such a strain upon the system, that it is of the first con- sequence to replace the waste by food and drink, and at the same time check it by appropriate treatment. The irritability of the stomach is a formidable barrier to alimentation ; nevertheless, every effort must be made to give food in small quantities and at short intervals. Should AFFECTIONS OF THE STOMACH AND INTESTINES. 1 93 the infant be at the breast, it may be allowed to nurse for a few minutes, every half-hour or hour. If hand-fed, it may be given the same foods recommended for entero-colitis, or chronic vomiting, in such quantities as can be retained, and at intervals corresponding in frequency to the smallness of the amount. Bits of ice and water should be allowed freely, even though they be rejected as soon as swallowed. To check the diarrhoea opium and astringents are neces- sary. A very serviceable formula is : — R. Liquor. Morphiae Sulph., f^j. Acid. Sulphurici Aromat., TT^xxiv. Elix. Curacose, f^ss. Aquae, q. s. ad f^iij. M. S. — One teaspoonful every two hours, for a child of six months old. With this, two drops of laudanum, suspended in two tea- spoonfuls of starch-water, should be administered, by the rectum, every three hours. Two or three times daily a mustard plaster (one part of mustard to five of flour) must be applied over the whole surface of the abdomen, long enough to redden the skin, and the whole body should be sponged several times a day with water at a temperature of 95 F. The clothing, diapers and person must be kept perfectly clean ; the sick-room must be as large and airy as can be commanded, and the infant must lie upon a bed, and not be constantly nursed on the lap. If it be possible, the patient should be sent early to the sea-shore or country, as this affords, by far, the best chance for recovery. Failing in this, morning and evening airings in a coach, or daily steamboat excursions, must be resorted to. Stimulants are needed from the first to ward off prostra- tion. From five to ten drops of whiskey in a teaspoonful 13 194 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. of lime-water may be given every two or three hours at the age of six months. When collapse sets in, the quantity of alcohol must be increased, and, if the stomach can bear it, a combination of stimulants is useful, as : — R. Spt. Frumenti, , . . f^ss. Ammonii Carbonatis, gr. xxiv. Syrupi Acaciae, f^j. Aq. Menth. Pip., q. s. ad f 5iij. M. S — One teaspoonful p. r. n. The temperature must be maintained by hot flannel wraps and hot-water bottles, and the child kept in a hori- zontal position and disturbed as little as may be. In this stage astringents are still indicated ; but opium must be used with great caution, or even discontinued en- tirely, when there are cerebral symptoms and semi-coma. In the fortunate instances in which this plan is successful, it is still necessary to treat the succeeding diarrhoea, and finally, to build up the general health by good food, tonics and fresh air. 8. INFLAMMATION OF THE COLON AND RECTUM— DYSENTERY. Dysentery is not a very frequent disease in children, but it may occur in an endemic or epidemic form, and as a sequel of measles, scarlet fever or variola. Morbid Anatomy. — The mucous membrane of the colon and rectum is swollen, red, softened and even loosened by diffuse suppuration, and the solitary glands are enlarged and ulcerated, while the corresponding peritoneal surface is congested. In severe and epidemic cases, the inflamed AFFECTIONS OF THE STOMACH AND INTESTINES. 1 95 surface presents more or less adherent pseudo-membranous patches, which, when removed, leave ulcers of irregular out- line and variable depth. Perforation and cicatricial contrac- tion of the intestine are occasional results. Etiology. — Sporadic and endemic cases are produced by the same causes as entero-colitis — excessive heat, bad food, and exposure to cold and wet. The epidemic form is certainly infectious, and there are grounds for believing that it is also contagious, although the last fact is not yet definitely established. The disease is most common in the second and third years of life, and seems to attack boys more frequently than girls. Symptoms. — Nausea, vomiting, high fever, and acute abdominal pain usher in the attack. Then the bowels be- come distended. The evacuations are numerous, ranging from four to forty a day ; small in quantity and voided with much straining. At first they contain faecal matter, but after a short time are composed entirely of mucus and blood, mixed with yellow or green flocculi, fragments of false membrane and pus. The blood may appear in dark red streaks or clots ; in black masses ; as a substance re- sembling the washings of meat, or merely diffused through the mucus, giving it a uniform red color. Their odor is most offensive. The face wears an anxious expression ; there is great rest- lessness, sleeplessness, muscular weakness, and rapid ema- ciation. The tongue is dry, red at the tip and edges, and covered in the centre with a brownish coating. There is anorexia and urgent thirst. The abdomen is distended, tympanitic, and painful on pressure, particularly over the course of the colon. As the attack progresses, tenesmus becomes the most permanent symptom; it occurs without the passage of stools, I96 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. and is often attended with prolapse of the rectum. Fever gives place to coolness of the surface ; restlessness, to semi- stupor; the eyes and cheeks sink ; the face becomes pinched, and death may take place quietly or be preceded by slight convulsions. The duration varies from two or three days in grave cases, to about two weeks in those that result favorably. The Diagnostic features are high fever, tenderness along the track of the large intestine, tenesmus and the number and character of the stools. The Prognosis is favorable in the sporadic form and when there is only slight elevation of temperature and moderately frequent stools. Quite the reverse, if there be high fever, great tenesmus, frequent evacuations contain- ing much blood or false membrane and pus ; when there is a tendency to collapse, and when the disease is epidemic. Relapses frequently occur. Treatment. — Children affected with dysentery must be kept at rest in the best room — so far as ventilation and cool- ness are concerned — that the house affords. Their diet should be liquid, and even this form of food must, on ac- count of the irritability of the stomach, be given in mod- erate quantities. From four to six ounces of whey and cream mixture; of flour-ball and milk, or arrow-root and milk, may be given every three hours to a child of two years. . A good preparation is : — Arrow-root, gj. Hot water, f£ ss - Mix thoroughly, and add to — Milk, fgij. Cream, f3 ss - Water, 13J. Small pieces of ice and moderate quantities of iced filtered water can be allowed to relieve thirst. AFFECTIONS OF THE STOMACH AND INTESTINES. 1 97 Two or three times daily the body should be thoroughly sponged with water at a temperature of 95 °R, and the abdo- men must be kept covered with a light flaxseed poultice, over the surface of which a little mustard has been sprinkled; this must be covered with oiled silk and changed as often as it becomes cold. If the patient be seen early in the attack, the medicinal treatment may be begun with a laxative, as : — R. 01. Ricini, fgijss. Pulv. Acacise, ^ij. Tr. Opii, TTLviij . Aq. Menth. Pip., q. s. ad fgij. M. S. — One teaspoonful every three hours, at three years of age. After this has been continued for twenty-four hours, there should be marked improvement in the evacuations. If this be not the case, it is well to order the fol- lowing : — R. Pulv. Ipecac. Comp., gr. vj. Bismuthi Sub-carb., gj. Pulv. Aromat., gr. vj. M. et ft. chart. No. xij. S. — One powder every three hours. With an enema of laudanum — gtt. iij to fSss of warm water — every four hours ; or a suppository of opium and acetate of lead : — R . Pulv. Opii, gr. ss. Plumbi Acetat., gr. j. 01. Theobromae, gj. M. et ft. supposit., No. vj. S. — One to be used every four or six hours. Should these fail, nitrate of silver may be administered by the mouth or rectum. If there be great rectal irritability and quick expulsion of the caustic injections, it is best to I90 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. follow them with enemas of laudanum. A good formula for administration by the mouth is : — U. Argenti Nitrat., g r - j- Tr. Opii Deod., Tl\xxiv. Syr. Acacise, f ^j. Aquae, q. s. ad f 3iij. M. S. — One teaspoonful every three hours. For an enema : — R. Argenti Nitrat., gr. j. Aquae Dest., f/>ij- M. S. — Inject twice daily, and allow an interval of twenty -four hours after three days' successive use. To ward off prostration, it is necessary to employ stimu- lants, in doses and at intervals proportionate to the demands of the case. Should collapse occur, alcohol and artificial heat to maintain the body temperature are the main resources. When convalescence is established, it is still necessary to guard the diet carefully and to build up the general health with tonics. Of these, the best are quinine with dilute nitro- muriatic acid, or tincture of nux with compound tincture of gentian, followed by ferrated elixir of cinchona, or citrate of iron and quinia. 9. TUBERCULAR ULCERATION OF THE IN- TESTINES. This form of ulceration commonly occurs as a complica- tion of pulmonary and abdominal tuberculosis. Gray gran- ulations may or may not be present at the site of lesion, but the special degenerative process in the intestinal mucous membrane is so intimately associated with tubercle that the term, " tubercular ulceration," seems to be warranted. AFFECTIONS OF THE STOMACH AND INTESTINES. 1 99 Morbid Anatomy. — The lesions are chiefly confined to the ileum, and primarily affect the solitary follicles and Peyer's patches, particularly those about the ileo-csecal valve. The follicles become enlarged from multiplication of their cell elements, then undergo caseous degeneration and softening, with the formation of isolated ulcers in the case of the solitary glands, and clusters of coalescing ulcers in that of the patches of Peyer. From having, at first, the shape of the follicles and patches, they gradually extend by a 'similar process of corpuscular infiltration, caseation and softening in the surrounding tissues. The fully-formed ulcers are irregularly oval in shape, with their greatest diameter directed transversely to the axis of the gut ; their edges are indented, thick and somewhat undermined ; their floors are red or gray, and formed by one or the other tissue of the intestine, as far down as the peritoneum, according to the depth of destruction. Perforation is rare on account of localized adhesive peritonitis. Gray granulations — a secondary product — may be found in the tunica adventitia of the small arteries and lymphatics, or on the reddened and cloudy peritoneal surface corresponding to the ulcers. Cicatrization takes place rarely, but may be the cause of stricture. The uninvolved mucous membrane is congested, thick- ened and softened. The mesenteric glands are enlarged and cheesy, and miliary tubercles are usually found in the lungs or elsewhere. Etiology. — The disease is met with in children who have passed the fourth year, and in whom the tubercular or strumous diathesis exists. Bad hygiene, bad food, and ex- posure, act as predisposing causes, by interfering with gen- eral nutrition and paving the way for the development of the diathetic tendency. An unsuitable diet, too, may indirectly 200 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. lead to this form of ulceration, by bringing about an ab- normal condition of the lining membrane of the bowel. Symptoms. — In addition to the features indicating a scrofulous or tubercular tendency, the child, after suffering for a variable time from the symptoms of simple intestinal catarrh, begins to have fever and to pass excessively offen- sive stools, composed of dirty-brown liquid that, on standing, deposits flocculi, mucus, pus and small, black clots of blood. There is colic preceding the evacuations ; moderate disten- sion of the belly, with tension of the parietes over the right iliac region, and tenderness on pressure there. Abdominal palpation also reveals enlargement of the mesenteric glands, and physical examination of the chest the evidences of pul- monary phthisis. Such cases usually result fatally, after a more or less protracted course, the direct causes of death be- ing tuberculosis of the lungs or of the meninges of the brain. Treatment. — Pure air, warm clothing, good food and tonics comprise the measures of treatment. The best of the tonics is cod-liver oil, which, in these cases, often seems to lessen the tendency to diarrhcea. Half a teaspoonful three times daily is quite enough for a child of five years. It may be given combined with maltine, or in an emulsion with lacto-phosphate of lime, or the compound syrup of the hypophosphites. The following is an admirable formula : — R. Olei Morrhuse, f ^ ij. Ext. Malt, (Dry) , Jjiv. Calcii Hypophos., Sodii Hypophos., aa gr. xvj. Potassii Hypophos., gr. viij. Glycerinse, f ^ ij. Pulv. Acaciae, ^ij. Aquse, q. s.adf^iv. M. S. — One teaspoonful three times daily. AFFECTIONS OF THE STOMACH AND INTESTINES. 201 In addition to this general treatment, attention must be paid to the intestinal condition. A light flax-seed poultice should be placed over the right iliac region or over the whole abdomen, or a dressing of cotton, covered with oiled-silk may be used. Internally, sub-nitrate of bismuth with compound ipecacuanha powder and nitrate of silver are useful ; at the same time it is well to administer clysters of laudanum. 10. COLIC. Colicky pains frequently attend dysentery, constipation and other intestinal disorders ; but colic with flatulence so uniformly occurs as a functional affection in children from birth to the end of the third month, and gives so much discomfort both to the infant and its attendants, by causing fretfulness, crying and wakefulness, that it demands separate consideration. Etiology. — In studying the causation of this condition, it must be remembered that after birth the infant, previously nourished through the blood of its mother, begins to take food through a new channel. Hence a new habit has to be formed, in addition to the development of a secreting and absorbing apparatus hitherto inactive. It is during this transition state that food of the best quality may be imper- fectly or slowly digested and flatulence and colic result. Food that is at all difficult to digest almost always occa- sions colic, and hand-fed babies are especially liable to it. Other causes are fulness of the stomach in over-feeding, or the opposite condition of emptiness after nursing at a breast that affords milk in small quantity, and, finally, inherited feebleness of digestive power, and over-sensitive- ness of the mucous membrane to the contact of food. 202 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. Symptoms. — Soon after feeding, the infant becomes rest- less, kicks his legs about uneasily, twists his body, grunts, or utters a series of piercing cries. The face is congested at first, from the effort of crying, but soon becomes pale, with a tinge of blue around the lips. The belly is full and hard, the hands and feet are cold, and, in bad cases, the fon- tanelle is more or less depressed. After a time, varying from a few minutes to an hour, eructations of flatus or of curdled milk occur, and the symptoms disappear for awhile. Such paroxysms may occur at any hour of the day, but are most frequent and severe in the evening and night. There is usually, also, a moderate degree of constipation, or the bowels are irregular. At night the rest is broken by uneasy tossing and whimpering, and during sleep a smile or an expression of pain often flits over the face ; but, in spite of the fretfulness and discomfort, the infant suffers little in general health, and increases in flesh and strength almost as rapidly as is normal. Treatment. — When the infant is fed at a healthy breast, it is of great importance to insist upon the rule of feeding only at proper intervals, and absolutely to forbid the habit of putting the child to the breast whenever it cries. Food will be taken whenever it is offered, and the warm milk entering the stomach relieves the pain for a time, only, how- ever, to increase it later by giving the viscus more work to do, and filling it with material to undergo fermentation with the production of flatus. Consequently, it is much better to resort to one of the preparations to be hereafter given for the relief of the pain. Should the child draw but a poor and scanty supply of milk, and the colic be due to emptiness, the breast must be supplemented by hand-feeding. Under these circumstances, and when the whole feeding is by bottle, much may be done AFFECTIONS OF THE STOMACH AND INTESTINES. 203 to prevent or relieve the attacks of pain by attention to cleanliness of the feeding apparatus ; by carefully selecting the ingredients of the food, and by adding an aromatic to the latter. A good food for a child of one month old is : — Milk, fgij. Cream, f^ij. Barley-water, f^ij- Caraway-water, fgj. Sugar of milk, . . . . , 3 ss * These ingredients are to be mixed in a clean vessel, poured into a perfectly clean bottle, and heated to a tem- perature of about 98°F. in a water-bath.* When the bowels are inclined to constipation, the barley- water may be replaced by a gruel made of ground oat- meal (Bethlehem brand). One or two teaspoonfuls of the meal to the quantity of water necessary for each bottle is the proper proportion. In place of this, a teaspoonful of Mellin's food may be added to the requisite quantity of water. The body should be anointed twice a day with warm olive oil, and enveloped in a broad flannel binder. It is even more important to keep the feet warm, and for this purpose thick socks or long woolen stockings should be worn, and in bad cases, artificial heat must be applied by hot water bottles. Medicines are indicated chiefly during the attacks of pain. A simple and serviceable prescription is ten drops of gin in a teaspoonful of sweetened warm water. Another is : — R. Sodii Bicarb., gr. xvj. Syrupi, f^ ss ' Aq. Menth. Pip., q. s. ad 'f^ij. M. S. — One teaspoonful p. r. n. for a child of one month. * A tin-cup half filled with water, placed on an ordinary stand over a gas- burner, makes a good water-bath for nursery use. 204 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. This is rendered more efficient by the addition of two drops of aromatic spirit of ammonia to each dose, or, in severe cases, one drop of spirit of chloroform. Bromide of potassium and chloral are most useful ; they may be combined as follows : — R. Potassii Bromidi, gr. xvj. Chloral Hydrate, gr. viij. Syrupi, f ^ ss. Aq. Mentha? Pip., q. s. ad f^ij. M. S. — One teaspoonful for a dose. Of this preparation, it is rarely necessary to give more than two or three doses, at intervals of half an hour. It is well to reserve this mixture for severe attacks, and in ordi- nary cases, to use the gin or the soda mixture. Should the paroxysm be so violent as to lead to depression of the fontanelle and threaten collapse, the infant must be placed in a warm bath for five minutes ; after being removed and carefully dried, he must be wrapped in a blanket ; a flax-seed poultice with a dash of mustard placed over the abdomen; a hot-water bottle applied to the feet; the bowels relieved by an enema of warm water, and ten drops of gin or brandy in warm water administered by the mouth. If the fontanelle still remain depressed, the stimulant must be continued in doses and at intervals proportioned to the urgency of the symptoms ; at the same time the soda and ammonia mixture may be given. As a routine treatment to improve digestion, it is well to order fifteen drops of wine of pepsin three times daily. AFFECTIONS OF THE STOMACH AND INTESTINES. 205 ii. HABITUAL CONSTIPATION. In addition to the locking of the bowels that results from mechanical causes, as intussusception, peritoneal adhesions, and so on, or from paralysis of the muscular coat of the intestine in certain nervous diseases, constipation of a func- tional character is a frequent and often an obstinate condition during childhood. Etiology. — Before the completion of the first dentition, it is more common in hand- fed babies than those nursed at the breast, and is due to the use of milk over-rich in casein ; the abuse of starchy food ; an insufficient supply of water, and often to the action of popular remedies given to relieve colic. With children who have passed the first dentition, constipation arises from faulty habits, and from the employment of a diet that is either bad in quality or unsuitable from its too great sameness. In all cases, in- herited sluggishness of the peristaltic movements must be remembered as a possible cause. Symptoms. — These vary greatly in degree. Thus, an in- fant, instead of the normal number, may have but one evacuation a day, or one, two and even three days may intervene between the movements. The stools are scanty ; composed of hard, dry, whitish lumps, and are voided with much pain and straining. Should the last symptom be severe, it is frequently attended by rectal prolapse and hemorrhage. Other features are colic, abdominal disten- sion, diminished appetite, occasional vomiting, feverishness, fretfulness, restless sleep, and, in bad cases, convulsions. In older children there may be one scanty passage each day, or a week at a time may elapse without relief. The stools, while lumpy and hard, are dark colored and mixed with mucus. The abdomen is the seat of pain, and may or may not be distended with flatus ; in the latter event, pal- 206 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. pation often reveals the presence of hard masses along the course of the descending colon. The tongue is coated ; the appetite capricious ; there is nausea and a sensation of dis- comfort in the rectum, leading to frequent, though unpro- ductive, straining efforts at defecation. There is also languor, irritability of temper, headache and restless sleep ; a muddy complexion and general spareness of frame. Diagnosis. — There is little difficulty in establishing the existence of habitual constipation. One must be cautious, however, not to place too much reliance upon the statement that "the child's bowels are open every day," for in obsti- nate cases, it is not unusual for daily evacuations of thin, worm-like masses to take place whilst the bulky and hard faeces are retained. Prognosis. — Proper management rarely fails in regulating the action of the bowels, but constipation may prove serious in two ways : first, by leading to faecal accumulation ; second, by generating a condition of general ill-health, during which the child is more exposed to the attack of acute and dan- gerous disease. Treatment. — In every case the relief of the actual state of retention of faeces in the rectum and the breaking up of the costive habit are the ends to be accomplished. For the former purpose, I prefer the use of purgative enemata and suppositories to the administration of the same class of.remedies by the mouth, particularly when abdominal palpation or digital examination of the rectum show that the retained mass is large and hard. The author's plan is to inject into the rectum, according to the age of the patient, from one to four teaspoonfuls of warm sweet oil ; allow it to remain for six hours, and then use one or more clysters of soap and warm water, or olive oil, soap and warm water.* * An enema composed of one teaspoonful of common salt to four fluid- ounces of warm water is very efficient. AFFECTIONS OF THE STOMACH AND INTESTINES. 207 The preliminary injections of oil soften the faeces, while the clysters — which must vary in bulk from one to six fluid- ounces, to be adapted to the capacity of the gut — have the additional effect of distending the walls of the rectum, and thus bring about muscular contraction and expulsion of its contents. Should the mass present at the anus but be too bulky to escape, more liquid may be injected, and if this fail, it must be broken up by the finger and its passage assisted by gently supporting the perineum during the straining efforts. In severe cases little result may follow a single application of this method, though a course of one or two oil injections and purgative clysters daily for several successive days will rarely fail to empty the bowel. When the soapy water and oil fail to produce expulsive efforts, the enemata may be rendered more efficient by the addition of a teaspoonful or more of castor oil or oil of turpentine. To make such an enema for a child of two years : — Take — One teaspoonful of oil of turpentine, Two teaspoonfuls of olive oil, The yolk of one egg. Mix thoroughly, and add, with constant stirring, to Four fluidounces of warm water. As with all injections, this must be thrown in gently, and the action of the syringe stopped as soon as pain is pro- duced. In infants, unless the rectum be very full, clysters give no better results, and are far less convenient than suppositories. At the age of two months the following prescription may be ordered : — R. Saponis, gr. vj. Olei Theobromse, gj. M. et ft. supposit. No. vj. S. — One to be inserted every morning or morning and evening. 208 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. Careful regulation of the diet is often all that is required to remove the tendency to constipation, and is a most important element of the treatment even in those cases where it is necessary to call in the aid of medicines. Bottle-fed babies must be fed upon cows' milk, so modi- fied by the addition of cream, sugar of milk and water as to be as nearly like human milk as possible ; and, should the bowels still remain confined, some laxative article, as Mel- lin's food or oat-meal, can be added. An admirable mixture for a child of three months is : — Milk, Hjiv. Cream, f^ ss - Sugar of milk, ^j. Bethlehem oat-meal (fine powder), gij. Water, f^iij- In preparing this, the water must be heated — just short of boiling — in a tin vessel, and the oat-meal added slowly, with stirring, until a smooth, white mixture be obtained; the other ingredients are then to be added, and the whole administered from a perfectly clean feeding- bottle. It is usually unnecessary to add the oat-meal to every bottle; one or two meals of it, each day, being sufficient. During childhood the food selected must be of good quality, thoroughly digestible and varied. Starches and meat are to be allowed in moderation ; pastry, salt meat and sweets forbidden, and a judicious use made of such articles as oatmeal or cracked wheat in the form of mush, well-cooked spinach, celery, cabbage and peas, baked apples, stewed prunes, thoroughly ripe peaches and pears, or the juice of oranges. To encourage peristalsis, warm sweet oil may be gently rubbed into the skin of the infant's abdomen twice daily ; AFFECTIONS OF THE STOMACH AND INTESTINES. 209 and with children more advanced in age, cold spongings of the belly, followed by frictions with a coarse towel until the surface is red, are very beneficial. The ordinary cathartics, castor oil and rhubarb, are not adapted to the treatment of habitual constipation, because their primary laxative action is followed by a secondary binding effect, and they consequently increase the original trouble. There are, however, other medicines of the same class that are free from this disadvantage, and one of them, or, better, a combination of several of them, may be em- ployed. For infants a very serviceable prescription is : — R. Mannse Opt., Magnesii Carb., . . . . aa >>ij. Ext. Sennse Fid., f^ss. Sympi, fjfj. Aq. Menth. Pip., q.s.ad f^iij. M. S. — A teaspoonful once, twice or three times daily for a child of six months. Or should a sallow skin, yellowish conjunctivae and loaded tongue indicate torpor of the liver : — R. Resinse Podophylli, gr. ss. Alcohol, ff^xlviij. Syrupi, q. s. adf^iij. M. S. — A teaspoonful two or three times daily for a child of one year. If it be difficult to make the infant take medicine, manna — which imparts only a sweet taste — may be dissolved in the food, and given from the bottle as often as required. Phosphate of sodium — an admirable laxative — can also be administered in the same way, in doses of five or ten grains three times each day, at the age of six months. Children of three or four years and upward do best H 210 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. upon aloes and belladonna. Tincture of aloes and myrrh in doses of five drops thrice daily, or in a single dose of ten drops at bedtime, acts well ; but if the patient be old enough to swallow a pill, the following prescription is to be preferred : — R • Ext. Belladonna;, gr. ss. Pil. Aloes et Myrrh., gr. vj. 01. Cari, gtt. iij. Ext. Taraxaci, gr. xij. M. et ft. pil. No. xij. S. — One pill at bedtime for a child of six years. Or the aloes and belladonna may be combined in a mix- ture,* thus : — R. Tr. Belladonnse, fgj. Tr. Aloes et Myrrh., f^ss. Mucilag. Acacias, q. s. Aquse Menth. Pip., q. s. ad f^ iij. M. S. — One teaspoonful for a dose. In using aloes and myrrh, it is usually necessary to re- duce the dose after a time, as its purgative action increases rather than diminishes with repetition. Another useful laxative is cascara, in the form of a fluid extract or an elixir ; of the first preparation ten drops, of the second, twenty drops may be given, once or several times daily to a child of six. The taste being pleasant, it may be * A clearer mixture may be made by using a solution of aloes and myrrh in- stead of the officinal tincture. The following is the formula : — R . Aloes, Myrrh, aa gr.ijss. Alcohol, fgss. Glycerins, f^j. Aqua;, q. s. ad f^iij. M. This solution was compounded, at the author's request, by Mr. J. J. Ottinger of Philadelphia. The dose is the same as the tincture. AFFECTIONS OF THE STOMACH AND INTESTINES. 211 administered without difficulty, and it does not lose its effects by repetition. I have lately used with much satisfaction a laxative con- fection, composed of tamarind pulp (gr. xxxvj) and senna in powder (gr.iv), aromatized with aniseed and lemon, and acidulated with tartaric acid. One of these may be eaten every evening, or as often as necessary, by a child of three years of age. They are regarded as sweets rather than medicine, and the little patients eat them readily. White wheat gluten suppositories,* melted and remade into one- half the original size for children under two years, are very useful. One may be inserted every evening, every morning and evening, or on alternate days, as the urgency of the case demands. 12. SIMPLE ATROPHY. Simple atrophy, or, as it is often termed, marasmus, is a condition in which there is extreme wasting of the soft tis- sues of the body, either without special organic lesions or with catarrhal inflammation of the mucous membrane of the gastro-intestinal canal. Morbid Anatomy. — After death, the muscular and other tissues are found in a state of atrophy, and there is a total disappearance of normal fat from the body. Fatty degeneration of the kidneys, lungs and brain may be dis- covered ; the stomach is sometimes ulcerated, and hemor- rhagic effusions into the cranium are not uncommon. Etiology. — Wasting usually occurs during the first twelve months of life, though it may begin in the second year, and is most frequently encountered among children of * Manufactured by the Health Food Co., of N. Y. 212 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. the poor. It arises both in breast-fed babies and in those brought up by hand, being, in either case, due to insuffi- cient nourishment. Food can be insufficient in two ways: first, when it is supplied in amounts too limited to meet the demands of the system ; and second, when it contains a minimum of the elements essential to nutrition, or presents them in a form ill adapted to the feeble digestive powers of infancy. For example, nursing infants waste in consequence of feeding either from a breast that yields too little good milk, or from one that secretes abundantly a poor, watery fluid entirely unfit for nourishment. With artificially fed children, on the other hand, it rarely happens that the quantity of food is too small ; the fault lies, rather, in the direction of quality. Undiluted cows' milk ; milk thickened with starchy mate- rials ; farinaceous foods, and even table food — meat, vegeta- bles, and bread — are given to babies a few weeks or months old. Now, all of these are highly nutritious, but the diges- tive apparatus is not sufficiently developed to prepare them for absorption. They are strong foods, adapted to nourish and strengthen much older children and adults, but as the infant cannot appropriate them, he starves as surely, if more slowly, than when taking no food at all. Such aliment, also, while remaining undigested in the stomach and intes- tines, undergoes fermentation with the formation of irritant products, causing vomiting or diarrhoea ; conditions that still further lower the vital powers and hasten atrophy. It is often possible to trace the disease directly to want of cleanliness in the feeding apparatus, and especially to the use of a form of bottle that has lately been very popular. This bottle has, in place of a plain gum tip, an arrangement of glass and rubber tubing of small calibre. One extremity of the rubber tubing, which is eight or nine inches long, AFFECTIONS OF THE STOMACH AND INTESTINES. 21 3 terminates in a small nipple-shaped tip and bone shield ; the other, after penetrating an ornamental rubber cork, is fitted to a bit of glass tubing long enough to extend quite to the bottom of the bottle. By this plan, the trouble of holding the bottle and keeping it at a proper angle during feeding is avoided. The seeming advantage, though, is counterbalanced both by the minor drawback that the child, left to itself, is apt to continue suction long after the bottle is exhausted, thus swallowing a quantity of air, and by the greater disadvantage that the tubing can never be kept clean. For a number of years the author has made it a rule to ask for the bottle of every hand-fed infant presented for treatment, and few days have passed without his seeing several of the complicated contrivances referred to. In almost every instance, notwithstanding the most careful and frequent cleansing, a sour odor could be detected, and if milk were present, it contained numerous small curds; while in cases of carelessness the odor was intolerable, and the interior of the tubing was encrusted with a layer of altered curd. With ordinary bottles, on the contrary, alterations in the character of the milk and coating of the interior of the tips were very infrequent. As there is little difficulty in keeping the bottles themselves clean, there can be only one reason for this difference, namely, in the old-fashioned instrument the nipple is readily removed and as easily in- verted and cleaned, but in the other there is no way of cleaning thoroughly the twelve or more inches of fine tubing. The latter cannot be inverted, and the passage of a stream of water, or of a small, stiff brush, only imperfectly removes the milk clinging to the interior. This, of course, soon undergoes decomposition, and in this state quickly inaugurates change in the next supply of milk placed in 214 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. the bottle. It is evident that a constant supply of food, no matter how good originally, thus rendered acid and partially curdled, must, like an excess of farinaceous or other unsuit- able food, produce irritation of the alimentary canal, inter- fere with the processes of nutrition, and lead to a state in which the features of wasting and disordered digestion are combined. The custom of preparing in the morning a supply of food sufficient for the whole day is another fruitful cause of atrophy. If this be done, no matter how carefully the mix- ture be proportioned, or how well adapted to the age and digestion of the child, it becomes unfit for consumption after standing eight or ten hours. The change may or may not be appreciable to the senses, but test-paper will always show acidity and the microscope demonstrate the existence of actively moving bacteria. Finally, food upon which a child has thrived for three or four months, perhaps, can become unsuitable and, conse- quently, lead to wasting, if the digestive powers be suddenly reduced by an intercurrent disease. Symptoms. — The clinical features differ materially, accord- ing to whether the element of insufficiency be one of quan- tity or quality. They may, therefore, be divided into two classes, viz : those developed by food that is suitable but not sufficient; and those resulting from unsuitable food. The first group of symptoms is most frequently en- countered in children who have been nursed at the breasts of feeble or over-worked mothers, in whom the milk is often both scanty and of poor quality. There is a gradual loss of plumpness; the muscles grow flaccid, and there seems to be an arrest of growth. The face is white ; the lips pale and thin, the skin harsh and dry or too moist, and the anterior fontanelle level or slightly depressed. The temper is irri- AFFECTIONS OF THE STOMACH AND INTESTINES. 215 table and sleep restless and disturbed, or the child is abnor- mally quiet, dozing constantly, and sucking his fingers until they become raw. When nursed, the child seizes the nipple ravenously; then, if there be little milk, he quickly drops it to cry passionately, as if disappointed at not being able to satisfy his hunger; but if the milk be abundant, though thin, he will lie a long time quietly at the breast and often fall to sleep with the nipple in his mouth. The bowels are inclined to constipation, the stools being scanty, hard and dry. Physical signs connected with the chest and abdomen are negative, and no indication of disease of any special organ of the body can be detected. In the second class, features of wasting are associated with those of irritation of the alimentary canal, and the symptoms altogether are much more grave than in cases of the preceding group. The subjects are almost invariably hand-fed infants. Emaciation progresses with a rapidity and to an extent depending upon the original strength of the child's consti- tution; the age at which artificial feeding is begun, and the sort of food employed. It is often so extreme that an infant several months old weighs less and appears smaller than at birth, and this, even after a large quantity of food, such as it is, has been consumed. The combination of great wasting with a voracious appetite, is very striking, and is only apparently contradictory, since hunger — the demand of the tissues for reparative material — cannot be appeased by food which, from its bad quality, is incapable of digestion or proper preparation for absorption and assimilation. Un- suitable food, too, by irritating the mucous membrane of the stomach, creates a fictitious appetite. Sooner or later the face becomes pinched, the eyes are sunken, the lips pale, and when moved display a deep fur- 2l6 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. row about the angles of the mouth ; the facial expression is uneasy or languid, and the anterior fontanelle is deeply de- pressed. The skin, generally, is dry, harsh and yellowish ; hangs in loose folds over the bones, and may be mottled by an eruption of strophulus or urticaria, or present red patches of intertrigo in the neighborhood of the genitalia and over the buttocks and inner surface of the thighs. The extremities are cold and the hands claw-like. The tongue is heavily furred or red and dry. With the mucous mem- brane of the mouth, it may be the seat of aphthous ulcera- tion or thrush deposit. As already stated, the appetite is often ravenous, and the cries of hunger are violent, oft repeated ; and only temporarily silenced by food ; thirst is increased ; colic is common ; the bowels are constipated, and the stools, which are voided with difficulty and straining, are composed of a few light-colored, cheesy lumps, partly covered with greenish mucus. Attacks of acute vomiting and diarrhoea often interrupt the regular course of the disease. At such times there is moderate fever during the night, though, ordinarily, the temperature is subnormal. Again, chronic vomiting and chronic diarrhoea * are apt to arise as complications, and greatly increase the danger of a fatal termination. Sleep is restless and disturbed, and many hours, particu- larly during the night, are spent in fretful crying. A com- mon group of symptoms connected with the nervous system is " inward spasms." When these occur, the upper lip becomes livid, somewhat everted, and tremulous ; the eye-balls rotate or there is a slight squint, and the fingers and toes are strongly flexed. They frequently usher in true convulsions. Sometimes the nervous manifestations are much more * See chapters on Chronic Vomiting and Diarrhoea. AFFECTIONS OF THE STOMACH AND INTESTINES. 217 complex. Thus, I have seen cases where there was retrac- tion of the head ; boring of the head into the pillow ; an approximation to the "gun-hammer" decubitus; general hyperesthesia and the tache cerebrale ; all suggestive of tubercular meningitis. Such symptoms disappear under an appropriate diet, with proper medicinal treatment, and are to be referred to an intensely excitable nervous system ; a condition depending upon insufficient nourishment, and differing merely in degree from that leading to "inward spasms." There is, of course, extreme prostration, the cardiac action is weak and the respiration shallow. The urine is citron-colored or very dark yellow ; has a specific gravity of 1009 to 10 1 2.5 ; a strong, characteristic odor, and is diminished in quantity. It is always cloudy or milky, only becoming clear on the approach of recovery. The sedi- ment deposited on standing, contains variously shaped cylinders ; fatty elements with tinted nuclei ; mucus ; colored uric acid ; urates in a crystallized or amorphous condition ; pigment, etc. The reaction is sometimes highly acid. The proportion of urates is decidedly, that of uric acid notably, and of coloring matter and extractives somewhat increased. Albumen is always present in variable quantity and sugar may be also frequently detected.* Death may be preceded by convulsions or the symptoms of spurious hydrocephalus, or may result from prostration. Diagnosis. — Great emaciation may result from inherited syphilis or acute tuberculosis, but both of these conditions are attended by characteristic symptoms, rendering their diagnosis a matter of little difficulty. When symptoms resembling those of tubercular menin- gitis are present, it is often necessary to delay a definite * " Parrot and Robin." 2l8 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. opinion. In simple atrophy, however, the open fontanelle is level or depressed; the belly is never scaphoid ; the bowels, though frequently constipated, are never locked ; vomiting is apt to be associated with diarrhoea; the respiration and pulse are regular in rhythm ; the temperature, as a rule, is sub-normal ; there is no hydrencephalic cry, and the antece- dent history and the course are different from the tubercu- lar disease. Prognosis. — A vast number of cases die annually in our large cities, yet the results of appropriate management are often rapidly and surprisingly successful. Patients should never be given up unless there be extreme wasting and prostration, or unless the symptoms of spurious hydro- cephalus arise; convulsions occur; or obstinate chronic vomiting or diarrhoea be developed. Treatment. — For the arrest of wasting from insufficient nourishment, the first thing to be attended to is the diet. Without entering at length into this subject,* it may be stated, as a uniform rule, that in selecting a diet the object should be to fix upon one suited to the age and digestive powers of the child, so that he may be able to digest, and, therefore, be nourished by, all the food consumed. Generally, infants under twelve months who have to be either partially or entirely "brought up by hand," do well upon cows' milk, with lime-water or with barley-water. The food should be administered from a bottle capable of holding half a pint, made of colorless glass, so that the least particle of dirt can be seen, and provided with a soft India- rubber tip. The whole quantity of food intended to be given in a day should never be prepared at once, but each portion must be made separately at the time of administration. Thus, a bottle of the sort described, absolutely clean, may * For the details of diet and general management, see Part III. AFFECTIONS OF THE STOMACH AND INTESTINES. 219 be filled with a mixture of one part of lime-water to two or three of sound milk, or with one part of barley-water to two or three of milk, to either of which may be added from one to two tablespoonfuls of cream and a teaspoonful of pure sugar of milk. The bottle must next be placed in hot water until the contents become warm, when it is ready for the child. The degree of dilution of the milk and the proportion of cream added vary with the age and the feebleness of diges- tion. Lime-water is the preferable diluent when there is frequent vomiting or acid eructation. Both it and barley- water are of service in preventing the formation of large, compact curds. After digestion has been brought into good condition by such a diet, the food may be cautiously increased to a standard suitable for a healthy child of the same age. At eight or ten months, from two to four fluidounces of thin mutton or chicken broth, free from grease, may be allowed each day in addition to the milk ; at twelve months, the yolk of a soft-boiled egg, rice and milk, and carefully mashed potatoes moistened with gravy; and at the end of the second year, a small quantity of finely minced meat. Once daily the patient should be bathed in warm water, or, at least, sponged over with warm water, and every morn- ing and evening a teaspoonful of warm olive oil or of cod- liver oil should be rubbed into the skin over the abdomen and chest. At the same time, the belly must be completely covered with a soft flannel binder, and the feet and surface generally kept warm by woolen clothing. In this way attacks of colic, if not entirely prevented, are rendered much less frequent and severe. If there be intertrigo, cleanliness and the free use of oxide of zinc ointment usually suffice to effect a cure. 220 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. Of medicines, bicarbonate of sodium, pepsin and cod-liver oil are, perhaps, the most useful. Cod-liver oil should not be given until the digestive powers have been brought into a comparatively normal state by proper food, antacids and digestants. The oil is most easily borne when given in emul- sion, and may be advantageously combined with lacto-phos- phate of lime or with the hypophosphites. Such symptoms as constipation, diarrhoea and vomiting demand, of course, appropriate treatment. 13. TYPHLITIS AND PERITYPHLITIS. Destructive inflammation of the coats of the caecum or vermiform appendix — typhlitis — and of the post-caecal areo- lar tissue — perityphlitis — are so closely associated that it is best to study them together. In the caecum and appendix the inflammatory process may stop short of ulceration; may proceed to ulceration with perforation and the production of perityphlitis, or, infrequently, may lead to the latter by simple extension of the morbid process without perforation. The independent and primary origin of perityphlitis is possible, perhaps, but must be extremely rare. Neither condition is, strictly speaking, an affection of childhood; nevertheless, children between four. and twelve years of age are liable, particularly to that form in which perforation of the vermi- form appendix occurs. Morbid Anatomy. — In typhlitis without ulceration, a large extent of the mucous lining of the caecum or appen- dix is the seat of catarrhal inflammation, while the investing peritoneum is opaque and injected, and may form adhesions to the neighboring intestinal loops. When the inflammation advances to ulceration, though a more limited area be AFFECTIONS OF THE STOMACH AND INTESTINES. 221 affected, there is a tendency to involvement, with destruc- tion, of all the coats of the bowel ; and during this process the peritoneal adhesions may become firmer and more extensive. The result of the perforating ulcer depends upon its position. Should it be situated on the anterior wall of the caecum, the intestinal contents escape into the peritoneal sack, in spite of the adhesions — which are rarely firm enough to offer an efficient obstacle — and produce a rapidly fatal general peritonitis. When, on the contrary, it occupies the posterior aspect, where the wall of the caecum is devoid of peritoneum, the escaping faecal matter enters the post- caval connective tissue, and causes inflammation, with sup- puration, and forms a " faecal abscess." Such abscesses may reopen into the intestine ; may extend down the sheath of the psoas muscle, reaching the surface below Poupart's ligament, or may point in the lumbar region or in any situation along the iliac crest. Sometimes the ulceration stops before perforation occurs, and the inflammation as- sumes a chronic form. In such cases, dense peri-caecal adhesions form ; the caecum is contracted in calibre ; has its walls thickened, and its mucous membrane either " almost entirely destroyed or converted into a retiform and trabecular fibroid tissue." * In the appendix the ulcer may be situated at the free extremity, or, more frequently, at some point in the lower third of the canal. As tb extent, the loss of substance may be small or involve the whole circumference. A col- lection of pus may be present in the cavity of the appendix, and it is usual to find a foreign body or intestinal concretion near the position of perforation. While the ulceration is going on, firm adhesions are occasionally formed with the * Meigs and Pepper. 222 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. caecum ; the anterior wall of the abdomen, or the tissues of the right iliac fossa. If the first event occur, the resulting circumscribed abscess opens into the intestine ; if the second, it points in the abdominal wall; and if the third, perityphlitis is set up, with the results already described. Usually, however, there are no adhesions or weak ones, and fatal general peritonitis follows the exit of the concretion and pus. The concretions resemble in shape and size cherry or date stones. They are hard ; often laminated in structure ; have smooth, waxy-looking surface; are grayish or brown in color, and are composed of earthy phosphates combined with inspissated mucus and faecal matter. Pins, shot and splinters of bone, strawberry seeds, hairs and little masses of hardened mucus, may form the nidus of these calculi. These articles, too, illustrate the class of foreign bodies which cause perforation when arrested in the vermiform appendix. Sir William Jenner, quoted by Eustace Smith, attributes the arrest of calculi in the appendix to malposition. " This process, owing to its length and the attachment of its mes- entery, may be bent at an angle (instead of being directed upward and inward) so that hardened particles can slip readily into it, but are prevented from returning." * Etiology. — In addition to peculiar anatomical rela- tions and physiological attributes, which render the seg- ment of intestine in question very prone to disease, a con- stipated habit is the chief predisposing cause. The exist- ence of the strumous diathesis, too, while it has little influence in increasing the susceptibility to typhlitis, does augment the tendency to ulceration and perforation after inflammation is established. * Diseases of Children, p. 678. AFFECTIONS OF THE STOMACH AND INTESTINES. 223 Retention of hardened faecal matter in the caecum, the so-called " typhlitis stercoralis " ; accumulation of the seeds of certain fruits, as strawberries or raspberries, in one of the pouches of the caecum ; the passage of these, or of intestinal concretions, or foreign bodies — shot, pins and bone spiculae — into the appendix, and the habitual use of coarse, undigestible food, are the most common excitants. Cold and exposure, blows upon the abdomen, and violent exertion with strain of the abdominal muscles, are also sometimes determining causes. In perityphlitis the inflammation is generally produced by the escape of faecal matter into the peri-caecal connective tissue. The perforation occasionally results from the ulcer- ation of typhoid fever or of intestinal tuberculosis. Symptoms. — Simple typhlitis begins suddenly, with pain in the right iliac region, and vomiting. The pain is con- stant and severe, and is increased by coughing, sneez- ing, vomiting and by efforts to stand or walk. The vomiting is attended by distressing retching ; is often re- peated, and the ejections consist, first, of food, and after- wards, of bile-stained fluid. The patient has an anxious face ; lies on his back slightly inclined to the right side, with the right thigh drawn up, and complains if an attempt be made to straighten it. Abdominal respiratory movements are partially suppressed ; the right iliac region is full and even prominent ; very tender to the touch and dull on percussion. Palpation, when it can be practiced, reveals a resistant mass occupying the site of the caecum. There is fever, indicated by a coated tongue, extreme thirst, a frequent and somewhat wiry pulse, and a temperature ranging about ioi° or 102 F. The bowels are confined. When properly managed, these symptoms disappear in from four to twelve days ; the bowels yield and move 224 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. freely with the expulsion of masses of hardened fasces ; the vomiting ceases ; the pain abates, and the tenderness and swelling slowly subside. Inflammation of the appendix alone is attended by the same symptoms. The pain, however, is more intense, and evacuation of the bowel is not followed by the same rapid relief. Perityphlitis may be ushered in by the marked symptoms just described. On the contrary, the causal ulceration, as it involves a limited area of the caecum or appendix, may be very latent. In the former instances the vomiting may stop, the bowels may be moved, and the acute pain be superseded by aching, or all discomfort disappear. The tenderness and swelling of the right iliac region, however, remain, although they are materially lessened; the patient looks ill; has a dis- tressed face, and is listless. If, as is ordinarily the case, the onset be latent, complaints are made only of dull aching or discomfort in the caecal region. These sensations are subject to exacerbations of a few hours' duration, when the suffer- ing becomes acute and there is vomiting and fever. In the intervals, the general health is somewhat below par ; the child, while up and about, takes little interest in play ; is peevish; has a poor appetite; is, perhaps, restless, thirsty and feverish at night, and has irregular movements of the bowels — attacks of diarrhoea alternating with constipation. After an indefinite time, in either case, perforation occurs. The event is followed by little change in the symptoms at first, but soon there is more constant and severe pain in the affected region, which is increased by movement or pres- sure ; there is greater fulness, too ; the bowels are confined ; sleep is more restless and disturbed, and there is more pyrexia. The child takes to his bed, where he lies on his back with the right thigh drawn up. If assisted to stand, AFFECTIONS OF THE STOMACH AND INTESTINES. 225 he rests his whole weight on the left leg, keeping the right bent at the hip and knee and rotated outward, and limps when he walks. There may be pain in the knee, and any rough attempt to move the leg increases the abdominal pain. As suppuration progresses in the peri-caecal tissue, hectic fever develops, with rigors or chills, followed by profuse sweating ; a dry, brown tongue ; diarrhoea ; a run- ning, feeble pulse ; prostration and rapid loss of flesh. The abdomen becomes distended and very painful ; the caeca! tumor increases in size, but becomes softer; there is pain in the right knee and ankle, and sometimes oedema of the leg. Should the abscess point toward the surface, the skin becomes swollen; doughy; dark-red or purple in hue; pal- pation yields emphysematous crepitation, and an incision gives vent to brownish offensive pus and fetid gas. When the abscess reopens into the intestine, the local pain, swell- ing and tenderness diminish, and the general symptoms improve. The uncommon cases in which perityphlitis occurs without previous typhlitis, are marked by pain ; deep ten- derness and moderate fulness ; but there is no tumor, in the right iliac region. The bowels are irregular, and there is colic and moderate fever. Perforation of the anterior wall of the caecum gives rise to the symptoms of local or general peritonitis, according to the presence or absence of firm adhesions. Ulceration of the appendix is more frequently followed by symptoms of general peritonitis than by those of perityphlitis, and the former may be the first indication of lesion of this portion of the gut. Diagnosis. — A sudden attack of pain referred to the right side of the abdomen ; vomiting ; constipation ; a pinched, anxious face; fever; a dorso-lateral decubitus; 15 226 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. flexion of the right thigh, and the presence of an intensely tender tumor in the csecal region, are the characteristic symptoms of typhlitis. Perforative ulceration may be suspected if these symp- toms disappear and reappear several times, or if, after a free evacuation of the bowels, local pain, tenderness and swelling continue. Intussusception resembles typhlitis in some of its fea- tures, but in this condition tenderness is a late symptom ; the tumor is situated more to the left of the abdomen ; some- times the lower end of the invagination can be felt in rectal examination, and there is severe tenesmus with the expul- sion of blood-stained mucus. The limping gait, with the pain and tenderness in the right groin which are incident to perityphlitis, may suggest hip-joint disease, particularly if other symptoms be but poorly developed. The distinction, though, can be made without much difficulty. In perityphlitis, although the right thigh is semi-flexed, and cannot be extended without great pain, it is possible, if care be taken, to rotate the head of the bone without causing suffering, and to make pres- sure on, or behind, the trochanter without giving discom- fort. The patient, too, while avoiding extension, will often freely flex, abduct or adduct the thigh as requested. Again, there is no atrophy of the thigh muscles, no flattening of the buttock on the affected side, and no lowering of the buttock fold or obliteration of the fold of the groin. Finally, the history shows an acute course, and there are usually other symptoms which directly indicate that the disease is situated in the right iliac region. Prognosis. — Simple typhlitis should almost uniformly terminate in recovery. The duration of active illness is, as already stated, from four to twelve days, though several AFFECTIONS OF THE STOMACH AND INTESTINES. 227 weeks often pass before the local tenderness entirely dis- appears, and the functions of the intestine are restored. Ulcerative destruction of the anterior wall of the caecum generally results in death from general peritonitis in two or three days. Perforation of the appendix is always rapidly fatal. The termination of perityphlitis resulting from perforation depends upon the direction taken by the pus. When the abscess opens upon the surface of the body the mortality is about fifty per cent. ; death resulting from exhaustion or ex- tension of inflammation to the peritoneum. A reopening into the intestine is more favorable, and many cases get well. Under any of these circumstances the course is apt to be prolonged. Treatment. — For prevention, it is necessary to guard against habitual constipation, by a properly selected diet, by regular exercise, and by enforcing the rule of making daily attempts to evacuate the bowels at a fixed hour. Nature may be assisted by a teaspoonful of compound lico- rice powder at bedtime, or one of the following pills : — I£ . Resin. Podophylli, gr. jss. Ext. Belladonna?, gr. j. Ext. Taraxaci, gr. xij. M. et ft. pil. No. xij. S. — One pill every night for a child of six years. Or— R. Ext. Belladonna, Ext. Nucis Vomicae, aa gr. j. Ext. Colocynth. Comp., gr. vj. 01. Cari, gtt. iij. Confec. Rosse, gr. vj. M. et ft. pil. No. xij. S. — One pill every night. Should there be a tendency to faecal accumulation laxatives are not to be administered, but the mass is to be 228 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. removed by purgative enemata. Two teaspoonfuls of table salt to a half pint of warm water, will be efficient for this purpose, or one of the enemata mentioned in treatment of constipation, (p. 20) may be used. A child attacked by typhlitis must be put to bed, and a small pillow placed under the right knee to support the thigh. The iliac region is to be covered with hot flax-seed poultices, or, if the child be robust and the tenderness and pain excessive, two or three leeches may be applied before poulticing. No food but milk, or milk with a little mutton or chicken broth, is allowable, and these are to be given in small quantities at short intervals. A patient six years old may take every two hours : — Milk, fgij. Barley-water, f 3 i j . Saccharated Solution of Lime, gtt. xv. Saccharated solution of lime is used as an alkali instead of lime-water, on account of its adding no bulk to the food : it is prepared in this way : — Take of — Slaked Lime, ^j. Refined Sugar, in powder, ^ij. Distilled Water, 13 xvj. Mix the lime and sugar by trituration in a mortar; transfer to a bottle containing the distilled water, cork and shake occasionally for a few hours. Finally, separate the clear solution with a siphon and keep in a stoppered bottle. When broth is used, it may take the place of the milk at three or four feedings during the twenty-four hours. Should the milk or broth not be retained, whey mixtures, pepton- ized milk, and meat juice can be tried. Thirst is best relieved by small quantities of cold car- bonic-acid water and bits of ice. The therapeutic indication is to relieve irritation and AFFECTIONS OF THE STOMACH AND INTESTINES. 229 arrest excessive peristaltic action of the bowels. This is best accomplished by a combination of opium and bella- donna, as : — R . Tr. Opii, Tiycxiv. Tr. Belladonnse, mjdviij. Aq. Cinnamomi, q. s. adf^iij. M. S. — One teaspoonful every two hours. The action of these drugs must be constantly pushed, until pain be relieved or the limit of systemic toleration be reached. The second or third dose usually checks vomit- ing ; but should this be not the case, morphia must be admin- istered hypodermically in doses of one-sixteenth of a grain at intervals of four or six hours, according to its influence on the pain and its narcotic action. As the pain subsides the bowels act spontaneously. There is one rule in the treatment of typhlitis that must never be forgotten, namely, no purge, no matter how gentle in action, is to be used, either by the mouth or rectum, while the acute symptoms are present. After they disap- pear, if the bowels be not relieved, enemata of warm water can be given safely, but no purge by the mouth. Furthermore, it is well to withhold the latter for several weeks after convalescence is established, for there may be some latent ulceration in progress that can only result favorably, through the formation of firm peritoneal adhe- sions, and nothing so surely destroys them, while in the process of development, as a purgative. As soon as the bowels are moved and convalescence begins, the diet may be cautiously increased; a belladonna plaster substituted for the poultices ; tonics administered, and the patient allowed to sit up in bed, and after a time, as health returns, to be up and about. Very active exertion should be avoided for several months. 23O DISEASES OF DIGESTIVE ORGANS IN CHILDREN. Perityphlitis demands the same rest in bed, careful diet- ing, local applications, and avoidance of purgatives. As hectic fever appears, the food must be more nutritious ; eggs, finely minced meat and beef-tea may be added to the milk. Alcoholic stimulants are also required with quinine, and, when there is great prostration, carbonate of ammo- nium. So soon as the abscess points it must be evacuated and a free discharge encouraged. In the after treatment every effort should be made to support the strength by good food, tonics and stimulants. 14. INTUSSUSCEPTION. In intussusception or invagination one portion of the in- testine is forced, from above downward, into another portion immediately continuous with it. Apart from faecal accumulation, this is practically the sole cause of intestinal obstruction in infancy. For, although instances are on record in which the bowel, in children, has been closed by peritoneal adhesions ; by a twisted vermiform appendix, and by morbid growths, these are but pathological curiosities. Two forms are met with, namely : — intussusception with- out symptoms ; and intussusception with symptoms. INTUSSUSCEPTION WITHOUT SYMPTOMS. This condition, which must be regarded rather as an accident than a disease, is frequently encountered in autop- sies upon young children who have met death from very diverse affections. Such intussusceptions occur shortly before, or during, the AFFECTIONS OF THE STOMACH AND INTESTINES. 23 1 death agony, and are probably produced by irregular and violent contractions of the muscular fibres of the gut. They consist simply of an involution of the bowel, without evidence of inflammatory action at the site of lesion, and can be readily reduced by traction. Sometimes there is but one inversion, though usually there are several ; as many as ten or twelve distinct invaginations, at distances of a few inches from each other, having been found in the same subject. The length of gut displaced is rarely more than three or four inches. The small bowel is the uniform seat; and of this division of the intestines, the lower part of the jejunum and the upper part of the ileum, are most fre- quently involved. Without a post-mortem examination, it is impossible to recognize the existence of this form of intussusception, on account of the entire absence of symptoms. Nevertheless, its discovery may be anticipated when death has resulted from cerebral or spasmodic diseases, or from acute or chronic entero-colitis. INTUSSUSCEPTION WITH SYMPTOMS. True intussusception is, fortunately, not very frequently met with in children, though it is more common in early infancy than in later childhood, youth or adolescence. Morbid Anatomy. — The probable mechanism of an in- tussusception is that a limited portion of the intestine con- tracts forcibly, and, by elongating and moving forward, enters a non-contracted segment immediately below, draw- ing in more or less of the latter, together with its mesen- tery or meso-colon, Next, new peristaltic movements force the invaginated bowel further and further along, until extension is arrested by resistance from the mesentery, or by secondary inflammatory adhesions. The intussusception 232 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. must, therefore, be made up of three layers of intestine, one above the other. The outer layer is called the sheath, or intussuscipiens ; the middle and inner ones, the intussus- ceptum. Of these, the external and middle have mucous surfaces in contact ; the middle and internal, serous surfaces. The involuted mesentery or meso-colon lies between the two last-named layers, and, on account of the firm attach- ment at its root, exerts a one-sided traction upon the intus- susceptum, curving it upon its axis and drawing the lower opening — which is elongated to a narrow fissure— from the centre toward the side of the sheath. The sheath itself is much folded or puckered, and on this account, with the curving of the intussusceptum, the apparent length of gut involved is always much less than the actual length. This varies from a few inches to several feet ; in extreme cases an intussusception beginning at the ileo-caecal valve, may become apparent to the touch or sight at the anus. In- crease in length -is accomplished by peristaltic action from behind; it takes place, always, at the expense of the exter- nal layer, and depends, for its degree upon the force of peristalsis, the width and laxity of the mesentery or meso- colon, and the amount and character of the contents of the intestine, behind the seat of involution. The results of an intussusception are, first, occlusion of the lumen of the canal with partial, or generally complete, arrest in the passage of the intestinal contents ; and second, obstruction of the blood current in the middle and inner tubes, due to pressure upon the mesenteric vessels. The obstruction of the circulation leads to deep conges- tion of the tissues of the intussusceptum ; the mass becomes purple and swollen ; the mucous surfaces exude a bloody material, and soon the opposed serous surfaces are glued together by inflammatory adhesions. AFFECTIONS OF THE STOMACH AND INTESTINES. 233 Should there be complete strangulation the intussuscep- tum becomes gangrenous, and, under favorable circum- stances, may be detached en masse or in pieces, and dis- charged through the anus. When this occurs, provided firm adhesions have formed, the sheath, being united at its upper extremity to the intestine directly above the point of inversion, forms, with the latter, a continuous tube, notwith- standing the separation of the intervening portion. Several accidents may happen during this process. Thus, the inflammation in the opposed serous coats may extend beyond the involution, and give rise to general peritonitis. Or, ulceration and perforation of the sheath may be pro- duced by the pressure and irritation of the free end of the intussusceptum. Again, when adhesions are imperfect, the contents of the intestine may escape into the peritoneal cavity through a rent, resulting from the separation of the sloughing intussusceptum ; and, finally, even after the gan- grenous mass is expelled, the adhesions may give way and permit extravasation. Generally, in those fortunate cases in which sloughing is followed by recovery, no permanent injury results from the cicatrization at the point of junction of the sheath and un- involved intestine. The cicatrix, though at first contracted, gradually stretches and a free passage-way is established. Sometimes intussusception is attended with so little con- striction of the involuted gut that the passage for the intestinal contents is quite free enough to allow of the maintenance of life for months, the patient finally dying of exhaustion. In infants the invagination is almost invariably ileo- cecal. The end of the ileum with the ileo-caecal valve is forced into the caecum, and, as the intussusception increases, penetrates further and further into the colon, drawing along 234 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. more of the ileum, and doubling in, first, the caecum, and then the ascending, or even the transverse and descending portions, of the colon. In some cases a few inches of the gut pass through the ileo-caecal valve before the caecum is inverted. Occasionally an intussusception involves the colon alone, and, very exceptionally, the small intestine. Upon opening the abdomen, in an ordinary case, much of the colon appears to be wanting, and a tumor is found occupying the left side or the left iliac fossa. This mass — the intussusception — is slate-gray in color; elongated or sausage- shaped, and doughy to the touch. By more or less forcible traction, the involution may be reduced, though the gut is usually softened and apt to be torn in the effort. If an incision be made through the sheath, exposing the intus- susceptum, two orifices will be observed at the lower end of the latter, one leading through the valve, the other into the cavity of the appendix vermiformis. The invaginated intestine is either of a uniform deep red color, resem- bling a long, firm clot of blood, or presents the appearances common to gangrenous and sloughing tissues. If death has occurred early, there are few evidences of inflam- mation between the serous surfaces ; if later, these are adherent, the adhesions extending a few lines beyond and above the neck of the intussusceptum on to the sound intes- tine. The gut situated above the point of obstruction is usually greatly distended with accumulated faecal matter and flatus ; whilst that below is collapsed and empty, or at most, contains a small quantity of mucus, stained with blood, pressed out from the capillaries of the strangulated mass. As the age of the child advances the more likely is the intussusception to be confined to the small intestine. Etiology. — As already indicated, early age seems to act AFFECTIONS OF THE STOMACH AND INTESTINES. 235 as a powerful predisposing cause. Of fifty-two cases in children, recorded by J. Lewis Smith, twenty-three oc- curred between the ages of three and six months ; eight between the sixth and twelfth month ; and eighteen between the first and twelfth years. Of Leichtenstern's four hundred cases, one-fourth occurred in the first year, after the third month. The greater liability in infancy is due partly to anatomical peculiarities, and partly to the want of regu- larity and the energy of the intestinal movements. Thus, in infants, the large intestine holds to the abdominal space that it is forced to occupy the relation of about three to one, necessitating doubling of the gut upon itself. At this time of life, too, the meso-colon is much wider than in later years, except where it passes over the kidneys, in which position it is very narrow, or even almost absent. These two conditions, combined with unrhythmical and violent peristalsis, cannot but favor involution. Many more males are affected than females. Rilliet and Barthez record twenty-five cases, all but three in boys, and the statistics of other authorities bear out their figures. The existing causes are imperfectly understood. Attacks have been attributed both to obstinate diarrhoea and pro- longed constipation ; to the presence of intestinal worms ; to the use of irritating and indigestible food ; and to external violence. Symptoms. — These vary considerably, according to the age of the sufferer and the completeness of intestinal ob- struction. In patients under one year the onset is abrupt, whether it occur in the midst of health, or during the course of some derangement of the digestive tract. The child is seized with intense pain in the abdomen, turns excessively pale, screams, and then cries violently, writhing and draw- 236 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. ing up his legs. The contents of the stomach are vomited, and usually, unless the bowels have been evacuated just before the attack, there is a single discharge of somewhat liquid feculent matter. After a time the pain passes away, leaving the little sufferer pallid and exhausted. There is now a rest from pain, but not from vomiting ; all food or medicines taken into the stomach are returned at once, either by the easy process of regurgitation, or by violent retching ; and if the viscus be empty, the ejections consist of a little bile-stained mucus, or even of blood. Sooner or later — the interval varying from a few minutes to several hours — there is another paroxysm of pain, accompanied by violent tenesmus, resulting in the evacuation of blood and mucus. At this time the abdomen differs little from its normal condition. There is no fulness nor tenderness, nor any tumor appreciable to the touch ; on the contrary, gentle friction often relieves the colicky pains, and the child prefers to lie upon its belly. The hands and feet may feel cool, though, otherwise, the temperature of the surface is unaltered. The mind is clear, but the expression of face is anxious, and denotes severe illness. The tongue may be lightly furred, and there is increased thirst, leading to a greedy consump- tion of the contents of the feeding-bottle, or a ravenous sucking at the breast. There is also restlessness, constant whining or moaning, and an inability to sleep. After a period of twelve or twenty-four hours, in which the par- oxysms of pain and tenesmus have grown more frequent and severe, the abdomen becomes full ; there is tenderness in the left iliac fossa, and if deep pressure be made in this region, during the absence of pain, a distinct swelling may be detected. The tumor gradually becomes more defined ; it is elongated or sausage-shaped ; of doughy consistence ; AFFECTIONS OF THE STOMACH AND INTESTINES. 237 and ranges in size from that of a hen's egg to that of a clinched fist. Later, it may change its position, moving toward the left side. When easily detected by external palpation, the tumor may be touched by a finger inserted into the rectum, and under these circumstances feels much like the cervix uteri in a vaginal examination. Occasion- ally the lower end of the involuted intestine protrudes from the anus, looking not unlike a prolapsed rectum. While these features are developing, vomiting continues, and bloody mucus is expelled, with great straining, from the rectum, but there is no passage of either faeces or flatus. The amount of blood varies considerably ; in some cases there is no more than sufficient to stain the diapers, in others, three or four ounces are voided several times daily. The tongue is red and glazed, or covered with a dry, brown coating ; the pulse becomes frequent and feeble ; the temperature rises to 102 or 103 F*; the abdominal respiratory play is restricted, and the flesh wastes. The urine may be greatly diminished in quantity ; this, how- ever, is by no means a constant condition, and seems to bear no relation to the seat or extent of the intussuscep- tion. By the third day symptoms of collapse set in. The face becomes pinched ; the eyes sunken and surrounded by dark circles ; the skin feels cool and clammy, and the ther- mometer indicates a sub-normal temperature. The attacks of vomiting are less frequent; the pain less intense; the bloody evacuations lessen or disappear, and the child lies upon his back, in an apathetic condition, with half-closed eyelids, until the end comes at some time between the fourth and sixth day. Occasionally death is preceded by convulsions. If, by any means, the invagination be reduced, the 238 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. vomiting stops, pain disappears, flatus and thin, copious, semi-liquid and offensive stools are voided, and the patient finds rest in sleep. Afterwards there is pallor, languor and weakness, though the appetite quickly returns and flesh and strength are soon regained. When older children are attacked the picture differs in some of its details. Thus, abdominal distension appears earlier and is more marked. The gut behind the position of obstruction being filled with faeces and flatus is greatly stretched, and the outline of its coils may be distinctly seen and felt through the tense wall of the belly. This is especially the case dur- ing the paroxysms of pain, when, too, waves of peristalsis may be seen, and loud, gurgling sounds heard. The tumor is large and better defined, and the dull percussion sound that it yields contrasts strongly with the general tympany. Vomiting is more apt to be stercoraceous. This charac- teristic symptom is absent in many cases, and very natu- rally so ; for, if Brinton's theory be adopted, namely, that faecal vomiting is due to a reverse axial current in the con- tents of the intestine, and not to anti-peristalsis, it is apparent that, for the development of this symptom at all, the obstruction must be either in the large intestine or in the lower part of the ileum. The date of its onset must depend upon the distance of the starting-point of the reverse current, or the obstruction, from the stomach ; upon the rapidity with which the bowel above is filled by inges- tion and secretion; and, should the colon alone be involved, upon the readiness with which the resistance of the ileo- caecal valve is overcome. Evacuations of blood are much less uniformly observed. Whether this symptom be present or absent depends solely upon the degree of constriction of the invaginate bowel. AFFECTIONS OF THE STOMACH AND INTESTINES. 239 When the constriction is just sufficient to obstruct the cir- culation and over-fill the vessels, hemorrhage is constant; but when there is actual strangulation, with complete arrest of circulation, no blood escapes. In older children stran- gulation is much more apt to occur than in infants, partly because the invagination more frequently involves the ileum or jejunum — which have a smaller calibre than the colon — and partly from the fact that in them, life being more prolonged after the accident, there is greater oppor- tunity for inflammatory swelling. Hence it is that in this class of cases there is, in many instances, absolute consti- pation without bloody stools, though in others, where the intussusception is ileo-caecal or colic, hemorrhage from the anus may be noticed as an early and permanent feature. The blood appears in a liquid form, mixed with mucus, or in small clots. It always has the venous hue, and is darker in color and smaller in quantity, in proportion to the distance of the involution from the anus. The older the child the more likely is gangrene, separa- tion and elimination of the invaginated gut, to take place. This result is usually noted during the course of the second week of illness, and can be attributed to the greater power of resistance and tenacity of life displayed by older chil- dren than by infants. It is a fortunate ending, but, unfortu- nately, rarely occurs at any age. After the process of separation is completed, violent straining efforts set in, expelling the black, ill-smelling, gangrenous mass, either in its entirety or in patches and shreds, together with a large quantity of dark, offensive, feculent matter. The child then falls into a deep sleep, and awakes much re- freshed. Thirst diminishes ; the appetite returns ; the par- oxysms of pain cease ; the face expresses ease and comfort, and the path to health is rapidly traversed. 240 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. When death occurs it is usually due to asthenia, and may, as in infants, be preceded by convulsions. General peritonitis is very uncommon. In addition to the form of intussusception just described, and which may be termed acute, a variety having a much more prolonged course, is sometimes encountered. Chronic Intussusception may occur at any age, and may exist for weeks, or even months, without producing severe illness. It originates most frequently in ileo-csecal intussus- ceptions, and depends upon the inflammatory union of the outer and middle layers, and the restoration of the permea- bility of the inner tube by the complete disappearance of swelling. The patient wastes, has periodical attacks of colicky pain, constipation and vomiting, and occasionally passes a little blood. Palpation reveals a tumor that alters its position, shape and density from time to time, and, on account of hypertrophy of the muscular coat above the partial obstruction, the knuckles of the intestine show dis- tinctly through the emaciated abdominal wall. Such cases may end in recovery, by separation ; or in death, by perforative peritonitis ; or by steadily increasing marasmus with chronic diarrhoea. Diagnosis. — Intussusception may be strongly suspected when a child in good health, or previously affected with simple diarrhoea, is suddenly seized with violent, paroxys- mal abdominal pain and vomiting, quickly followed by straining efforts, resulting in the evacuation of mucus and blood, and by intense prostration. The suspicion will be reduced to a certainty if, at the same time, it be possible to detect a sausage-shaped tumor on the left side of the belly, or to touch the lower end of the inverted intestine upon rectal exploration. It is necessary to remember, however, that often, at the commencement of the attack, there is a AFFECTIONS OF THE STOMACH AND INTESTINES. 24I single loose feculent stool, and also that, in older children, bloody, mucous discharges may be entirely absent. The diseases with which intussusception is most likely to be confounded are simple colic, perforative peritonitis, dys- entery and faecal accumulation within the bowel. In simple colic, the pain, though often severe, is never distinctly paroxysmal. It is attended by suppression of urine, is relieved by the discharge of flatus per anum, and is followed by copious urination. During the attacks the skin may be hot, and the belly is usually hard and tense. There is no vomiting, tenesmus or discharge of bloody mucus. The misfortune of confounding intussusception with colic can hardly be overestimated ; for a laxative, as castor-oil, while relieving the latter by clearing out the intestinal canal, cannot fail to aggravate the former by increasing the force of the peristaltic contractions. In perforative peritonitis there is pyrexia from the be- ginning, the abdomen is distended and tense, and pressure in the right iliac region — since the seat of perforation is usually the vermiform appendix — produces pain. On the other hand, tenesmus and the evacuation of blood and mucus from the rectum are never observed, neither is it possible to detect a tumor by abdominal palpation, nor the lower end of an intussusception by rectal ex- ploration. Dysentery presents, in the character of the dejections and the severe pain and tenesmus, features similar to intussus- ception, but it lacks the sudden onset, the obstinate vomit- ing and the abdominal tumor. The two diseases differ, too, in their course. A faecal accumulation, as it produces actual occlusion of the intestine, has many symptoms similar to invagination. Thus, there is vomiting, colicky pain, tenesmus, constipa- 16 242 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. tion and a tumor. The former accident, however, is pre- ceded, for some time, by the passage of hard and scanty- stools ; while the attendant vomiting is less obstinate ; there are no bloody evacuations ; and the tumor is more superficial, more fixed, and of such consistence that it can be indented by moderately firm pressure with the fingers. A purgative enema, also, rapidly leads to the expulsion of the impacted mass and relieves the symp- toms. Prognosis. — Every case of intussusception affords an out- look that is grave in the extreme, though the danger to life de- pends directly upon two factors, namely : the age of the pa- tient attacked, and the acuteness and consequent severity of the symptoms. In children under one year, death almost in- variably results. With those who are older, the constitutional resistance being greater, sloughing of the intussusception is more apt to take place and recovery follow ; but the rarity of this fortunate termination, at any time of life, has already been alluded to. Treatment. — In no other disease does the prospect of success rest so much upon an early diagnosis and appro- priate management. The indication to be met is the total arrest of all action of the muscular fibres of the intestine. To accomplish this end, the patient must be kept in a state of absolute repose ; must be made to take enough opium to relieve pain and check intestinal peristalsis, and must be carefully and prop- erly fed. Opium may be employed alone or in combination with belladonna, and may be administered by the mouth, by the rectum or, in children over a year old, by hypodermic injec- tion. A combination of the two drugs and their administra- tion by the rectum is to be preferred in ordinary cases. For AFFECTIONS OF THE STOMACH AND INTESTINES. 243 a child of one year the following suppository may be or- dered: — R . Ext. Opii, gr. jss. Ext. Belladonnae, gr. ss. 01. Theobromse, gij. M. et ft. supposit. No. xij. In the beginning, one of these suppositories can be intro- duced every two hours ; but the interval must be lessened or the dose increased to the point necessary to relieve pain and tenesmus. When the mouth is selected as the channel of exhibition, the opium and belladonna may be prescribed in a mixture, as: — R. Tr. Opii Deod., f^j. Tr. Belladonna, f 3 ss. Aquae Anisi, q. s. ad f| iij. M. S. — One teaspoonful every two hours (or p. r. n.) for a child of one year of age. When the hypodermic method is selected, it is still best to combine the two drugs, thus: — R. Morphise Sulphatis, gr. i. Atropise Sulphatis, g 1 "- 2V Aquae Dest, f^j. M. S. — Inject ten minims p. r. n., in a child of six years. The application of anodynes to the surface of the abdo- men has certainly some power in relieving pain, and should, consequently, not be neglected. For this purpose a piece of soft flannel, large enough when doubled to cover the whole belly, should be dipped in hot water, wrung moderately dry, sprinkled with a teaspoonful of laudanum, laid over the surface and covered with oiled silk. As to food, only so much as is absolutely required to sustain life should be allowed. For the first twenty-four or 244 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. forty-eight hours, especially if there be vomiting, food may be altogether withheld, and a teaspoonful of barley-water or a small bit of ice given every fifteen minutes to allay the thirst. Later, milk and barley-water for infants, and milk, beef-juice or strong beef essence for older children, are admissible ; but always in minimum quantities and at inter- vals of two or three hours. Thus, for a child of one year, half an ounce of milk and barley-water, in equal parts, every two hours, will be quite enough ; while at the age of six years two ounces of milk, one ounce of beef-essence, or half an ounce of beef-juice, every three hours, will suffice. It is well to peptonize the food, as in this way it is prepared for assimilation, and little residue is left in the intestinal canal. Everything must be taken cold. When the strength begins to fail, brandy must be admin- istered. The following mixture is a good food and stimu- lant :— Brandy, 4 fluidounces. Cinnamon water, 4 fluidounces. The yolks of two eggs. White Sugar, y z ounce. Rub the yolks and sugar together, then add the cinna- mon water and spirit. Dose. — A dessertspoonful to two tablespoonfuls every two hours, according to the age. Should the patient be seen before the fourth day of the attack, in addition to the above measures of treatment, efforts should be made to reduce the involution mechan- ically. Mechanical interference can be successful only before inflammatory adhesions have formed, and is contra- indicated when there is tenderness over the seat of lesion. There are three possible ways of accomplishing reduction, viz., by taxis, by forced injection of water, and by insuffla- tion of air. To perform either of these successfully the AFFECTIONS OF THE STOMACH AND INTESTINES. 245 patient, unless an infant under one year, must be previously put thoroughly under the anaesthetic influence of ether. Taxis consists in kneading and otherwise manipulating the abdomen with the warmed and oiled hand ; it is usually employed in conjunction with one of the other methods. If forced enemata be resorted to, the child is placed upon his back in bed, with the buttocks elevated, so that the trunk is inclined at an angle of 45 degrees. Then, with a Davidson's or Fountain syringe, the physician him- self must inject, carefully and slowly, as much tepid water as the capacity of the intestine will permit. While this is being done, the abdomen must be kneaded in such a manner as to force the water upward along the bowel in the direction of the invagination. At times the ob- struction can be felt to give way ; but the best proofs of this fortunate occurrence are the subsidence of the more urgent symptoms and the onset of sound sleep. Soon, too, there is a discharge of bloody mucus from the rectum, and then a free, offensive, semi-fluid faecal evacuation. Insufflation of air is suited to those cases in which the intussusception having descended into the rectum, little or no water can be injected or retained. The apparatus for this purpose consists of a bellows, having its nozzle at- tached, by means of a piece of flexible rubber tubing, to a caoutchouc tube about a foot in length ; the latter is inserted into the rectum, care being taken to secure a perfect fit at the anus by a packing of lint. The air should be pumped in slowly and gently, and during its introduc- tion, taxis is practiced in the same manner as in the forced injection of water. Should these measures fail, or should the case be seen for the first time after the third or fourth day, the question 246 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. may arise as to the propriety of laying the abdomen open and reducing the intussusception by direct traction. For the details of the operation of laparotomy, the reader must be referred to works on surgery. Briefly stated, it consists of making an incision in the median line of the abdominal wall ; opening the peritoneum ; finding the intussusception, and working it back at the neck in the same manner that a hernia is reduced. The practical results of the operation prove, beyond doubt, that there is very little to be expected from it. This is espe- cially true in the case of infants less than a year old, amongst whom it has been invariably fatal. By its performance, too, the chance of recovery from separation of the strangulated intestine is lost. Upon this point, Prof. John Ashhurst, Jr.,* states : — "Inspection of the table (comprising 13 cases of lapa- rotomy, 5 in children), shows, in the first place, that no encouragement is afforded to repeat the operation in very young infants. The only instances in which it has been resorted to during the first year of life have all terminated fatally (Gerson, Wells, Weinlechner). But when it is re- membered that of Pelz's 162 cases (all occurring in chil- dren), no less than 91 were in infants less than a year old, it will be seen how large a proportion of cases must at once be put aside as unfitted for operative treatment. It is very true that the fatality of intussusception at this early age is enormous, the mortality being, according to Leich- tenstein's elaborate statistics, no less than 86 per cent. But the case is very different from that, for instance, of an operation for imperforate rectum ; for in this condition there is necessarily no hope but in an operation ; whereas, in the case of intussusception, experience shows on the one hand * American Journal of Medical Sciences, July, 1874. AFFECTIONS OF THE STOMACH AND INTESTINES. 247 that, even at this age, a certain number do recover without operation, and that, on the other hand, as might be ex- pected, operative treatment is in such cases of no avail. " In the second place, the table shows that in what may be called acute cases, those, namely, in which in addition to symptoms of obstruction there are evidences of strangula- tion, such as peritonitis and intestinal hemorrhage, a resort to operative inference will be productive of no benefit. These cases are, on the other hand, as justly remarked by Mr. Hutchinson, precisely those in which there is most hope of recovery by sloughing of the invaginated portion. " There remains, then, a limited number of cases, in not very young infants, in which the symptoms are those of obstruction merely, without intestinal hemorrhage or peri- tonitis, and in which, when other measures fail, the question of operation may properly be considered." When separation and discharge of the invaginated seg- ment of the intestine takes place, it is necessary to exert the utmost care lest the new-found adhesions be broken down. The patient must lead a passive life ; the food must be readily digestible and restricted in quantity, and all farinaceous and fermentable articles are to be excluded from the dietary. In chronic intussusception great reliance can be placed upon the free administration of opium and belladonna, with forced enemata ; or, in proper cases, insufflation of air, and as this condition generally occurs in late childhood, lapa- rotomy, when other measures fail, may be undertaken with more hope of success. 248 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. 15. INTESTINAL WORMS. The common parasitic worms that find their habitat in the human intestines may be divided into two classes, each including several varieties, namely : — {Oxyuris vermicularis. Ascaris lumbricoides. Tricocephalus dispar. {Tcenia solium. Tcenia saginata. Bothriocephalus latus (rare). Of these, the oxyuris vermicularis — small thread-worm — and the ascaris lumbricoides — long, round worm — are most frequently found in children. The taenia, or tape-worm, is uncommon before the age of six or seven years. DESCRIPTION AND MODE OF ENTERING THE BODY, Oxyuris Vermicularis. — These worms are silvery-white in color and of small size ; the males being one-sixth of an inch, the females one-half an inch long. To the unaided eye they present the appearance of small, white threads. They inhabit the caecum and whole length of the colon, but are most abundant in the sigmoid flexure and rectum, where they derive nourishment from the faeces, and where, alone, they give rise to symptoms or evidences of their presence. Oxyures enter the body by direct passage of the ova into the mouth. They are introduced clinging to fruit and various articles of food, or are conveyed to the lips by the hands of the child previously used to relieve itching, occa- sioned by the presence of the parasites in the neighborhood of the anus. Having entered the stomach, the embryos are liberated by the action of the gastric juice and pass into the AFFECTIONS OF THE STOMACH AND INTESTINES. 249 Fig. 2. Egg of Oxyuris Vermicularis. small intestine, which they descend with the food, develop- ing so rapidly that they become sex- ually mature by the time they reach the caecum. The eggs, as seen by the microscope, are ^ of an inch in length, ovoid and unsymmetrical. They are produced in great numbers, each female giving birth to several broods, numbering from ten to twelve thousand, and they are ex- tremely tenacious of vitality. Ascaris Lumbricoides. — This parasite has a certain su- perficial resemblance to the common earth-worm. It is cylindrical, tapering at both extremities, is reddish or brown- ish in color, has a body marked with fine transverse rings, and possesses a peculiar, disagreeable odor independent of the substance in which it lives. The head of the worm pre- sents three prominent labial papillae surrounding the mouth, and the tail is conical. The male is from three to six inches in length and one-eighth of an inch in thickness, with an incurved tail and a penis consisting of a pair of slender, clavate, chitinous spicules, the ends of which protrude from a cloacal aperture at the root of the tail. The female meas- ures from six to fourteen inches in length and one-fourth of an inch irt thickness. The genital aperture is situated on the ventral surface, near the anterior third of the body; the ovarian tubes may be observed as long, tortuous canals, and the uter- ine tubes as short, straight canals; the latter contain many millions of ova. The ripe ova are laid in the intestine, and are expelled, with the t . , • FlG - 3- stools, in great numbers, sometimes Egg of Ascaris Lumbri . even in large masses. The eggs coides. 250 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. are -^ of an inch in diameter, and are oval, with a thick, elastic, brownish, double shell and nodulated surface. After expulsion from the rectum, they are very tenacious of life, remaining in a condition capable of development for several years. This is particularly the case when tljey find their way into water or moist earth. Here the embryos slowly de- velop. It is not positively known in what way children become infected with the parasite, but impure water is, without doubt, the medium. Recent experiments on both animals and men have demonstrated that infection cannot be directly produced by taking the recently laid, ripe ova into the stomach. It is probable, therefore, that the ova passed by an infected subject, after entering — through drainage or other- wise — moist soil or running water, and undergoing partial development, are eaten by some common, but unknown, minute aquatic animal. Within the bodies of these they are still further developed, so that, when the animalculi are in- gested with impure drinking water, and the embryos liber- ated by the action of the digestive solvents, the latter are in a position rapidly to assume their mature characters. Lumbrici inhabit the small intestine principally, though they frequently migrate. Their number in a single indi- vidual may vary from two to several hundreds. Tricocephalus Dispar. — The whip-worm, as this para- site is sometimes called, is yellowish- white in color, with the anterior half, or more, of the body attenuated in a hair- Fig. 4. like manner. The male is about one Egg of Tricocepha- inch and a half in length, has the thick lus Dispar. por tion of the body enrolled, and a blunt tail. The female is two inches long, with a conical tail. The eggs of this worm are laid in the intestine and AFFECTIONS OF THE STOMACH AND INTESTINES. 25 1 voided with the faeces ; nothing is known of their subse- quent history, or of the method in which the human being is infected. Whip-worms inhabit the lower end of the ileum, the cae- cum and the vermiform appendix, and feed on the intestinal contents. They are met with in small colonies, varying in number from two to twelve. Their occurrence is considered to be exceptional in this country, but this may be explained in two ways : first, as they are rarely voided with the faeces, like other worms, they escape ordinary observation ; and second, as their presence gives rise to no symptoms during life, few think of looking for them on the post-mortem table. Tjehije infest children over the age of six years with almost the same frequency as adults. Of the three varieties, the tcenia saginata, beef tape-worm, and tcenia solium, pork tape-worm, are the most common, while of these two the former is met with in by far the greater number of cases. The tcenia saginata is a soft, yellowish-white, band-like worm, varying in length from six to twenty or more feet. The head has about the bulk of a yellow mustard-seed, is rounded quadrate, and provided with four hemispherical suckers. Between the head and body is a short, unsegmented, flattened neck, narrowest at its upper extremity and gradu- ally broadening as it merges into the body. The latter is dis- tinctly segmented. The first segments are several times wider than long, but become successively larger until the length exceeds the breadth two or three times ; their number may reach twelve hundred, and the largest measure from one-fourth to one-third of an inch in Fig. 5. width, and a quarter to a full inch in length. Egg of t ^ nia The parasite is usually solitary. It inhabits 252 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. the small intestine, in which position the segments, as they ripen, are spontaneously detached, some having already expelled their burden of eggs (often numbering 35,000), others still laden. Both eggs and liberated segments then become mixed with the intestinal contents, pass down- ward into the colon, and are finally expelled with the faeces. The mature ova are brown, oval in shape and of minute size; they have a thick inner shell, and an outer longitudinally striated envelope. Each ova contains an embryo — a spherical or oval body — having at one pole three pairs of divergent, boring spiculae. In rural districts, it is a very common habit, with both adults and children, to stool in a fence corner, or other more or less secluded spot, at any time there is a call for evacuating the bowels. Should ova-laden tape-worm seg- ments or liberated eggs be contained in the faeces so care- lessly deposited, these are apt to be swallowed by cattle grazing in the neighborhood. Having once entered the stomach, the embryos, liberated from the eggs by the action of the digestive solvents, attach themselves to the mucous membrane of the viscus, perforate it by means of their powerful boring apparatus, and, either directly or through the medium of the blood current, migrate into the tissues of the body, usually the muscles or liver. After attaining their destination, they become fixed and slowly undergo development, dropping the spiculae and being transferred into the larval form or scolex. The scolex consists of a head like that of the mature worm, with a neck terminating in a capacious cyst, within which the head and neck are inverted. In this form each parasite is surrounded by a sack of connective tissue ; the new formation depending upon the presence of the larva, acting like an imbedded foreign body. The flesh, liver and other organs of cattle AFFECTIONS OF THE STOMACH AND INTESTINES. 253 so infected are said to be " measly." Now should measly beef be taken into the stomach insufficiently cooked, or should it be administered raw — a frequent practice in the treatment of certain intestinal diseases — the parasite, during the process of digestion, is liberated from the investing connective tissue envelope, everts its head from the con- taining sack, attaches itself to the mucous membrane of the small intestine, feeds upon the intestinal contents, and, growing from its caudal extremity rapidly develops into a mature tape-worm. The time required for development has been proved by experiment to be less than two months, and the natural duration of life is very protracted. Taenia Solium. — This species of tape-worm enters the human body through the medium of measly pork. The methods of propagation and development are identical with those of the taenia saginata. In general appearance, also, the two worms are very similar. The pork tape- worm, however, is white in color and broader and shorter, the usual length being between five and ten feet. The head, which presents the most prominent distinguishing features, is about the size of an ordinary pin ; it is spheroidal in shape, is surmounted by a blunt papilla, encircled by a double row of hooks, and, at the same time, has the four hemispherical suckers to be noticed in the beef tape-worm. The ova are somewhat smaller but otherwise identical, the scolices, long known as Cysticercus celluloses, likewise possess the double row of hooks to the head, and in this way may be distinguished from the larvae of the other variety of taenia. The period occupied in development is about three months ; the length of life probably twelve years or more. As in the United States pork is but little used as food in comparison with beef, and when used is usually thor- 254 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. oughly cooked, the difference in the frequency of occur- rence of the two species of worms can be readily explained. In regard to this point, Prof. Leidy states : " Since the writer distinctly recognized the beef tape-worm, within the last twenty years, all the specimens of taeniae, from people of Philadelphia and its vicinity, that have been submitted to him for examination — perhaps in all about fifty — have appeared to belong solely to taenia saginata. The preva- lence of this species with us is no doubt due to the common custom of eating underdone or too rare beef, while the pork tape-worm is comparatively rare, as with us pork is only used in a well-cooked condition." Symptoms — These may be divided into two classes : gen- eral and special. The general symptoms are those always present, irre- spective of the particular species of worm infecting the pa- tient. They depend not so much upon the mere presence of the parasite, as upon the peculiar condition of the mucous membrane of the alimentary canal which accompanies and is, perhaps, essential to their development and existence. This condition is one of catarrh, with an excessive produc- tion of mucus, or, to give it a definite title, mucous disease; consequently, the general symptoms of worms are similar to those already studied under this head (p. 140). The patient wastes, and the face is pale or leaden in hue, dark circle^ surround the orbits, the eye-balls are sunken, the pupils dilated and the upper lip swollen. The skin generally is muddy, covered with dry, epidermic scales, and devoid of natural softness and elasticity. The lips and mucous membrane of the mouth are pale, the breath is offensive and the tongue is flabby, with the edges indented by the teeth and the dorsum covered with a thin, slimy coating, or it presents one or other of the conditions AFFECTIONS OF THE STOMACH AND INTESTINES. 255 described (pp. 142, 144) as pathognomonic of mucous dis- ease. There is often moderate hypertrophy of the tonsils and swelling of the lymphatic glands at the angles of the jaw. The appetite is capricious, sometimes almost absent, and at others insatiable. Nausea, and acid eructations and vomit- ing are common. Constipation is the usual state of the bow- els; occasionally there is tenesmus, with constant unproduc- tive efforts at defecation, and there is a liability to attacks of diarrhoea, attended with great straining and the passage of black, slimy, ill-smelling motions. Free mucus may be discharged from the rectum, and, in girls, from the vagina. The abdomen is always distended, feels hard on palpation, and to percussion yields a tympanitic note. Constant com- plaints are made of pain in the belly, especially in the neighborhood of the umbilicus. Its character varies, being in some cases tearing or cutting ; in others, simply an uneasy, creeping sensation, and in others still, a sensation of cold- ness. The urine is frequently voided with pain and difficulty, and may have a turbid, milky appearance. The pulse is weak, altered in frequency and occasionally irregular; a harassing, paroxysmal cough may be present, and not uncommonly there is sighing, sobbing and hic- cough. The child's temper is altered; he becomes irritable or sullen ; his sleep is broken by bad dreams or night terrors ; and there are many and very diverse nervous manifestations, such as annoying itching of the nose, temporary delirium or stupor, sudden blindness, loss of voice, squinting, fixation of the eye-balls, vertigo and general convulsions. These features, of course, are not equally marked in all cases, their degree depending upon the grade of intestinal catarrh. 256 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. Special symptoms — those due directly to the presence of the worms — differ according to the species. The Oxyures occasion violent itching at the anus, es- pecially at night, when they prevent sleep and lead to troublesome scratching. This irritation, transmitted to the genitalia, combined with the constant application of the hands to these parts, produces erections in the male, and may induce the habit of masturbation in both sexes. Two conditions of the bowels are observed; either forcible but ineffectual straining, often attended by prolapsus ani, or diarrhoea. Finally, the oxyures may, on inspection, be dis- covered moving about in the radiating folds of the anus. Occasionally, these parasites migrate into the vagina, uterus, urethra, oesophagus and stomach. When they occupy the vagina, they give rise to leucorrhcea. Lumbrici occasion more or less pain in the umbilical re- gion ; also vertigo, convulsions, and even chorea. The irri- tation of their presence may cause chronic diarrhoea, with scanty, offensive, thin, mud-colored stools, voided with much straining, and most numerous during the night. They often migrate into the stomach, whence they are quickly expelled by vomiting. Less frequently they pass into the common bile-duct and gall-bladder ; also the nose, larynx, trachea, larger bronchi, vagina, urethra and bladder; in each position giving rise to symptoms of irritation. They have been found, too, in abscesses communicating with the intestine, having escaped by entering a preexisting fistulous opening, or, perhaps, in some instances, by directly perforating the gut. These abscesses usually occupy the abdominal wall in the umbilical or inguinal regions, or are seated in the substance of the liver. As already stated, the Tricocephalus dispar causes no special symptoms. AFFECTIONS OF THE STOMACH AND INTESTINES. 257 Taeniae are attended by sensations of weight and gnawing in the abdomen; occasional attacks of colic, and distension, particularly of the umbilical region. With a huge appetite, there is progressive emaciation and general lassitude. A persistent headache is sometimes a feature, and there may be annoying cramps in the muscles of the legs and arms. Diagnosis. — While the occurrence of the symptoms de- tailed strongly indicate the presence of worms, the only positive proofs of their existence are the discovery of the parasites themselves or of their eggs in the stools ; their appearance, as in the case of oxyures, at the margin of the anus ; and their expulsion, as in the case of lumbrici, from the stomach in the act of vomiting. Therefore a purgative, by emptying the intestinal tract and expelling some of the parasites, is the crucial test. In some cases the symptoms are severe enough to suggest tuberculosis or tubercular meningitis; though a mistake may be readily avoided by bearing in mind this possibility and applying the test. Prognosis. — Intestinal worms rarely cause death. When a fatal termination does occur, it results from convulsions ; from the consequences of the migration of the parasite into the bile-duct and air passages, or from some secondary affection ; proving dangerous because the strength of the frame attacked has been sapped by its guests. Treatment. — The diagnosis having been established, either by the spontaneous appearance of the worms or by their discovery after the administration of a dose of calomel or calomel and rhubarb, remedial measures must be directed to the accomplishment of two objects : 1st, the expulsion of the worms; and 2d, the removal of the alkaline mucus — the essential nidus — and the restoration of the alimentary canal to its normal condition. 17 258 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. 1st. For expelling the parasites, the anthelmintic to be chosen depends upon the infecting species. Oxyures, as they inhabit the rectum, are within the reach of enemata, and are best treated by them. The object being to kill the worm, it is essential thoroughly to empty the lower bowel by an enema of warm water, immediately before injecting the parasiticide, so that the latter may come in contact with the mucous membrane, upon which the great mass of the worms lie. One or two medicated injections can be administered daily ; they act best when cold, and their bulk should not be so large as to distend the gut and lead to a quick return ; from one to two fluid- ounces is the proper quantity for a child of two years.* Liquor caicis ; common salt and water, in the proportion of one teaspoonful to a pint; a solution of castile soap, thirty grains to a pint of water ; or one of sulphuret of potassium, twelve grains to a pint ; oil of turpentine in milk ; half a teaspoonful to four fluidounces of pure olive oil; and lard beaten up with water until it become liquid, all constitute good injections, the last two having the property of quickly relieving itching, in addition to their parasiticide action. In my experience, however, the injection of an infusion of quas- sia has been most uniformly successful. It is best to order the quassia chips and have the infusion prepared in the nursery, thus : — R. Quassia? (rasped), £ij. S. — Place in a porcelain vessel and pour on a pint of boil- ing water, macerate for two hours, then strain and inject two fluidounces once or twice daily. With children past the second year the proportion of quassia may be gradually increased to one ounce, at the age of seven. * All of the succeeding directions for treatment are adapted to children of this age. AFFECTIONS OF THE STOMACH AND INTESTINES. 259 While employing enemata it is well to aid their action and relieve itching at the anus, by anointing the parts with some mild mercurial ointment, and at the same time push- ing a little into the rectum. A good preparation of this kind is — R . Hydrargyri Chloridi Mitis, gr. lxxx. Unguenti Petrolei, Jj. M. S. — Apply morning and evening. When there is intense rectal irritation, an injection of laudanum and starch water (gtt iij to f jj) and cold com- presses applied to the fundament, give great comfort. Diarrhcea and tenesmus are to be overcome by the administration of a teaspoonful of castor-oil, with five drops of paregoric once, twice or three times daily, according to circumstances. Should there be constipation, one tea- spoonful of Husband's magnesia, or the appropriate dose of some other saline, must be given every morning until the symptoms disappear. Besides keeping the bowels regular, it is well to secure several free watery evacuations, at inter- vals of three days, for the purpose of dislodging any oxyures that may be inhabiting the upper part of the large intestine, and of clearing away accumulations of mucus ; to accomplish this saline, cathartics are to be selected. Against Lumbricoides a number of drugs bear an anthel- mintic reputation. Of these, santonin, spigelia and cheno- podium are the most efficient. To insure the greatest success, the patient for whom either of these medicines is ordered, must be placed on a restricted liquid diet, that the alimentary canal may be as empty as possible ; and during their administration the bowels must be kept active by cathartics, that the dead worms and the ova may be swept away. Broken doses of the purgative chosen can be com- 2(3o DISEASES OF DIGESTIVE ORGANS IN CHILDREN. bined with the anthelmintic, or an occasional full dose may be given during the course of the treatment. Santonin is almost tasteless, and when combined with sugar is readily taken by children; it may be prescribed in the following ways : — R. Santonini. gr. vj. Sacchari, gr. xxx. M. et ft. chart. No. xij. S. — One powder morning and evening, each second dose to be followed by two teaspoonfuls of castor-oil or a purgative dose (gr. j) of calomel. Or— R. Santonini, gr. vj. Hydrarg. Chlorid. Mit., gr. vj. Sacchari, gr. xxiv. M. et ft. chart. No. xij. S. — One powder morning and evening. Santonin sometimes produces xanthopsia, or " yellow- seeing ; " this is of no importance and quickly disappears after the drug is discontinued. It is best, however, to advise the mother or nurse of the possibility Qf this occur- rence. Occasionally, too, it increases the flow of urine and gives the fluid a reddish color. Spigelia is a very useful remedy, though as it simply narcotizes the worm it must always be administered in association with a purge. The officinal preparation, ex- tractum spigelian et sennae fluidum, is as good a combina- tion as can be employed; it may be given in doses of one teaspoonful three times daily. If it be desired to make success doubly sure, it is well to add santonin : — R . Santonini, gr. iv. Ext. Spigeliae et Sennae Fid., f^j ss - Syrupi, f,l ss - Elix. Simplicis q. s. ad f^iij. M. S. — Two teaspoonfuls three times daily. AFFECTIONS OF THE STOMACH AND INTESTINES. 26 1 Chenopodium is a very safe, non-irritant anthelmintic, being especially indicated when the evacuations are in- creased in number, are liquid and contain mucus or blood. The volatile oil may be administered dropped upon a lump of white sugar, in doses of five drops three times daily. A purgative is then necessary, every twenty-four or forty- eight hours, or, for convenience, both remedies may be combined in a mixture : — R. Olei Chenopodii, f 3 ij. OleiRicini, fSJ ss - Olei Cinnamomi, tt\v. Syr. Acacise, q. s. ad f^iij. M. S. — One teaspoonful three times daily. Should there be reason to suspect ulceration of the bowel, five minims of oil of turpentine added to each dose of this formula will both improve the condition of the mucous membrane and increase the specific action. The only disadvantage possessed by oil of chenopodium is that it is not so acceptable to the taste or stomach as either santonin or the liquid extract of spigelia and senna. Whip-worms, when detected, can be removed by the same means as lumbricoides. Taeniae are the most difficult of the intestinal parasites to eradicate; evacuations of many feet of segments are easily brought about, but reproduction steadily continues until the head is finally expelled. This portion is obstinate in its adherence to the intestinal mucous membrane, and being minute in size is easily shielded from the action of the parasiticide by the tenacious mucus which is always se- creted in excess when a tape-worm is present. It is essential, therefore, to diminish, or, if possible, entirely remove, this secretion, before commencing the 262 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. actual treatment. For one week the child * must take the following prescription : — R. Ammonii Chloridi, gij. Ext. Sennae Fid., f 3 v j- Inf. Gentianae Comp., q. s. ad f 5iij. M. S. — One teaspoonful before each meal. At the same time the diet must be restricted, and non- farinaceous in character ; for instance : — Breakfast at 8 a.m. — A tumblerful and a half (12 oz.) of milk, with two slices of gluten bread.f Luncheon at 12 m. — A teacupful (4 oz.) of milk. Dinner at 2.30 p.m. — A bowl (8-12 oz.) of beef, mutton, or chicken broth ; two slices of gluten bread. Supper at 7 p.m. — Same as breakfast. For drink at dinner or between meals only pure filtered water in small quantities. At the end of the week's preparation one of the anthel- mintics particularly adapted to this species of worm may be ordered. Of these there are several : — Oleoresin of male fern — oleoresina filicis — mentioned first, because most commonly used and generally efficient, should be given in one or two drachm doses, either floating upon a little (fSss) peppermint water or in a mixture, such as : — R. Oleoresinae Filicis, f^ij-iv. Syr. Acaciae, f ^ ij. Aq. Cinnamomi, q. s. ad f ^j. M. S. — Tablespoonful for a dose. The plan of administration has much influence on the issue. For the best result, the patient, unless much debili- * The succeeding formulae are adapted to children of six years. f Gluten flour can be obtained in any of the larger cities, and is made into bread in the same manner as wheat flour. AFFECTIONS OF THE STOMACH AND INTESTINES. 263 tated, must, upon the day on which the treatment is insti- tuted, begin a fast after his dinner ; in the evening two fluidrachms of castor-oil should be given ; next morning, after the bowels have been thoroughly evacuated, a dose of fern ; and three hours later, a second dose of castor-oil. A few hours subsequently the worm will probably be ex- pelled. During the interval, occasional sips of water may be allowed to relieve thirst. The nauseating taste of the oleoresin of fern may lead to its quick rejection from the stomach ; in such cases the viscus should be quieted by a few drops (3-5) of McMunn's elixir of opium, and a second dose of the anthelmintic administered after the lapse of half an hour. Kameela (Rottlerd) is another good remedy for tape- worm, possessing the advantage of being in itself an aperient, and hence doing its work without the aid of purgatives. The same period of absolute fasting is necessary, as when administering male fern, and on the morning of the day following the beginning of abstinence, two doses of fifteen grains of powdered kameela must be taken, at an interval of three hours. The drug may be exhibited suspended in syrup or in mucilage of acacia, a few drops of some aro- matic oil being added in either case. A capital prescription, containing both kameela and male fern, is : — R. Kameelae, gr. xxx. Syr. Acaciae, f ^ ij. Misce, et adde — Oleoresinse Filicis, fgj-ij. Aquae Cinnamomi, f ^ j. M. S. — To be taken in two doses at an interval of three hours. A formula very similar to this has been in long and most successful use at the Children's Hospital, Philadelphia. In some cases, oil of turpentine is very efficient, even 264 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. when the remedies already mentioned fail. This may be given in one large dose, or in small doses frequently repeated. By the former method, from two to four flui- drachms are given in the morning after the usual fast, and followed in three hours by a dessertspoonful of castor-oil, unless the bowels have been previously relieved. To carry out the latter, the following mixture may be used : — R . Olei Terebinthinae, Mellis, aa f^ss. 01. Menth. Pip., gtt. vj. Mucilag. Acaciae, q. s. ad f^iij. M. S. — Two teaspoonfuls every six hours. Every second day, preferably in the morning, two grains of calomel must be administered. Other useful drugs are pomegranate rind and pumpkin seed; the first in the form of a decoction of the bark of the fresh root (Sij-Oj), six ounces to be taken in three doses one hour apart, while fasting; the second as an electuary, six drachms of the seeds being beaten up with sugar, and taken in one or two doses; a brisk purge must be ordered after either. Koosso and its active principle, koossin, are recommended by some authorities. One drachm of the powdered drug suspended in water, or five or ten grains of koossin in capsule are the proper doses for a child of eight years. To prevent nausea, it is better to break the dose into two or four; additional purgative is usually not required. After administering the anthelmintic, it is impossible to decide at once whether the tape-worm has been eradicated or not unless the head be discovered in the stools. The physician must not trust to the mother or nurse to find the head, but must look for it himself. The stools immediately AFFECTIONS OF THE STOMACH AND INTESTINES. 265 following the action of the parasiticide must, therefore, be preserved until his visit; the chamber in which they are received being filled with water containing a small quantity of carbolic or salicylic acid. This is to be gently shaken in order to separate the worm from the faeces, and then allowed to stand for ten minutes ; during which the parasite, from its greater specific gravity, sinks to the bottom of the vessel. Next, the supernatant liquid is poured off, the vessel refilled with water, and the process repeated until the fluid remains nearly colorless. Then the head, if present, is readily found. Should the head not be discovered, it is impossible, although all symptoms may disappear, to give a positive opinion as to complete expulsion until two or three months have passed. Any return of symptoms requires a second course of treat- ment. 2d. The removal of the alkaline mucus and the restora- tion of the normal condition of the alimentary canal are to be accomplished by the same attention to diet and the same therapeutic measures recommended when discussing chronic gastro-intestinal catarrh (p. 145). CHAPTER III. CASEOUS DEGENERATION AND TUBERCULO- SIS OF THE MESENTERIC GLANDS— TABES MESENTERICA. Cheesy degeneration of the mesenteric glands, existing alone, or in association with tubercular deposit, is far from being a common disease. The majority of cases occur after the third year, and under this age tabes mesenterica is rarely encountered. Morbid Anatomy. — The glandular lesions are identical with those so familiar in scrofulous conditions. Usually some of the mesenteric glands remain healthy ; and those involved — a variable number — do not present a uniform degree of alteration. A few are simply hyperaemic and slightly swollen from an increase in the corpuscular elements; some are increased in size and spongy in texture ; others, again, are enlarged to the size of walnuts, dense, dry and anaemic looking; and still more are partially or completely converted into opaque, yellow, cheesy masses, and sometimes contain tuberculous deposits. The diseased glands may remain isolated, but often unite into an irregular mass of variable size. This mass is situ- ated in mid-abdomen, rests upon the vertebral column, and is movable or fixed according to the freedom or involvement of the mesentery in the swelling. Further changes are softening of the caseous material, with suppuration and discharge through the gland capsule — an unusual event; shriveling of the gland into a fibrous mass, through thickening and contraction of the trabecular 266 CASEOUS DEGENERATION OF MESENTERIC GLANDS. 267 of the reticulum ; and — quite commonly — a gradual hard- ening and shrinking by the absorption of fluid and the deposition of earthy salts. Together with these changes, it is the rule to find scrofu- lous lesions of the superficial lymphatic or bronchial glands, cheesy or tubercular deposits in the lungs, and ulceration of the mucous membrane of the intestinal canal. Some- times, also, tubercular peritonitis and caseous and tubercular deposits in the liver and spleen are discovered at the post- mortem examination. Etiology. — As the disease always occurs in strumous subjects, the predisposing causes are the same as those leading to the production of that diathesis. The exciting causes are embraced under three heads — imperfect hygiene, disease of other organs, and infection through the milk of diseased cows. Children who live in filthy, over-crowded, dark and ill- ventilated houses, are much more likely to be affected than those born to more fortunate surroundings ; but of all hygi- enic factors, coarse, over-stimulating or bad food is the most potent for evil. This acts by irritating the intestinal mucous membrane and producing catarrh and follicular ulceration. Tubercular disease of the lungs, scrofulous disease of the cervical and bronchial glands or of the bones and joints, and tubercular ulceration of the bowels, are not only usual associates, but, no doubt, frequent causes of tabes mesen- terica. In addition, measles and scarlet fever, from their tendency to induce inflammation of the mucous membrane of the bowels and glandular hyperemia, must be ranked as exciting agents, and so, also, must difficult dentition and whooping-cough. Attention has recently been directed to the possibility of the transmission of tubercle to the intestinal tract by means 268 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. of the milk of diseased cows. In support of this theory, Klebs has made a number of experiments, from which he draws the conclusion that the use of the milk of cows having advanced phthisis, always produces tuberculosis, which be- gins as an intestinal catarrh and extends to the mesenteric glands. Symptoms. — The signs elicited by physical exploration of the abdomen, and the symptoms arising from the presence of a large mass of glands are much more characteristic than the general features. The shape of the belly and the tension of its walls may be perfectly normal. Such is generally the condition during the earlier stages of the disease ; later, and particularly when there is intestinal ulceration, there is con- siderable distension. This is due either to the accumulation of flatus in the bowel or to the large size of the glandular tumor. In the first instance, the degree of prominence varies from day to day ; when marked, the wall is tense, percussion is tympanitic, and it is difficult or impossible to grasp the glands ; in the second, the enlargement is constant and greatest in and about the umbilical region ; here there is resistance to the palpating hand rather than tension ; the tumor is easily felt, and percussion over it gives a dull sound ; around it, a tympanitic one. The tumor varies in size from that of a hen's egg to that of a double fist ; it is nodulated, hard, somewhat tender, slightly movable when small, and fixed when large. When of any size, the mass can readily be touched by placing the fingers on the um- bilical region and pressing backward toward the spine. Otherwise, it is well to put one hand on either side of the abdomen and gently bring them together toward the. median line, the patient being placed on his back with his shoulders and thighs elevated so as to relax the parietes ; by this method, it is possible to detect a tumor as small as a walnut. CASEOUS DEGENERATION OF MESENTERIC GLANDS. 269 The secondary manifestations of the presence of a large mass of glands in the abdominal cavity are pains and cramps in the legs, due to pressure upon the nerves ; and oedema of the legs and distension of the superficial abdominal veins, from compression of the great venous trunks. The veins are often very prominent, and ramify over the wall of the belly to join those of the thoracic wall, which are also dis- tended. If the glands in the notch of the liver be enlarged, direct pressure is exerted upon the portal vein and ascites results ; this, however, is a very unusual symptom. Provided the naturally prolonged course of the disease be not abridged by tubercular or other complication, the ten- dency is for the glands to shrink and become calcareous. This change lessens the size of the tumor, diminishes the tension of the parietes, and, by relieving pressure, leads to the disappearance of the secondary derangements. Softening is another, but, fortunately, a rare termination. Adhesion may then take place between the gland and a loop of intestine, so that the softened matter is evacuated into the bowel without harmful result; but should the dis- charge be directly into the peritoneal cavity, acute perito- nitis is set up, and death soon follows. The general symptoms depend for their development upon the condition of the intestinal mucous membrane. Usually there is scrofulous ulceration, with or without general catarrh. If ulceration and catarrh be associated, the child wastes ; grows pale and feeble ; presents a haggard appearance ; is fretful and peevish ; has a capricious appetite and much thirst; complains of wandering pains in the abdomen, and is affected with diarrhoea, attended by the expulsion of offen- sive, dark, watery stools, which, on standing, deposit flaky 27O DISEASES OF DIGESTIVE ORGANS IN CHILDREN. matter, mucus, and small, black blood clots. Sleep is rest- less, and at night the temperature rises one or more degrees above normal. When catarrh is absent, the bowels are often constipated ; the patient looks ill ; is pale and languid ; his muscles are flabby, and he has more or less flatulent pain in the belly; but there is no marked wasting and none of the evidences of great impairment of general nutrition. Should there be no disease of the mucous lining of the bowels, flesh is retained ; the spirits and strength are good ; the appetite and bowels undisturbed; the temperature normal, and there is nothing to show ill-health save some pallor of the skin. Diagnosis. — The only positive proof of the existence of tabes mesenterica is the detection, by palpation, of a glandu- lar tumor. Particular caution must be given against the mistake, so frequently made, of attributing every case of abdominal distension to disease of the mesenteric glands. Prominence of the belly is a frequent symptom in children, and in the vast majority of cases depends upon intestinal catarrh. In this condition there is imperfect digestion and assimilation of food, and, consequently, debility, affect- ing the muscles of the intestines as well as the system generally. Now, imperfectly digested food readily under- goes fermentation, with the production of carbonic-acid gas, and this distends the bowels ; the more so as they are want- ing in tone from the weakness of their muscular coat. Such inflation of the gut must lead, of course, to a prominent abdomen, but one which is uniformly tympanitic on percus- sion, moderately soft and flaccid to the touch, and entirely free from the signs of enlargement of the mesenteric glands. Again, distension of the superficial abdominal veins is merely an indication of obstructed circulation in the deep CASEOUS DEGENERATION OF MESENTERIC GLANDS. 27 1 venous trunks, and only becomes a symptom of importance in the diagnosis of tabes mesenterica when hepatic disease can be excluded. Even should a tumor be felt, the question arises whether it may not be an accumulation of faeces. In the latter there is no tenderness ; the mass occupies the position of the transverse or descending colon, is oblong in shape, with its long diameter corresponding to the axis of the gut in which it is placed, and is so soft that it may be somewhat moulded by the pressure of the fingers. Should there be any doubt, an enema of warm water and soapsuds must be thrown into the bowel and retained for a few moments, by firm pressure upon the anus. When expelled this will bring away a quantity of light-colored, brittle matter, if the mass be due to faecal accumulation ; and the previously detected tumor will be found, on examination, to have dis- appeared or lessened in size. On the other hand, if the tumor be glandular, the expulsion of flatus and faeces, induced by the injection, only renders it still more promi- nent. The diagnosis must not be considered completed by the detection of the tumor, but must extend to the discovery or elimination of the different complications : — ulceration of the intestines, tubercular deposits in the lungs and tuber- cular peritonitis. Prognosis. — Caseation of the mesenteric glands is dan- gerous, but the danger does not spring from the glandu- lar disease so much as from the affections that produce it, the conditions that accompany it, and the results that fol- low it. In regard to the latter, though, it may be stated that of all the glands in the body the mesenteric are least likely to be followed by ill consequences when diseased ; a fact due to their slight tendency to undergo softening. 272 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. When the sole discoverable lesion is swelling of the glands, and there is no rise in the evening temperature nor marked impairment of nutrition, the hope of subsidence of the enlargement and ultimate recovery, may be reasonably entertained. On the contrary, if there be wasting, diar- rhoea and fever, indicating ulceration of the bowels, sec- ondary, perhaps, to chronic disease of the lungs, the prognosis must be grave. Again, the occurrence of tuber- culous peritonitis renders the prospect most unfavorable. Treatment. — Much may be done in the direction of prophylaxis by keeping a strict watch upon the stomach and intestines in scrofulous children, so as to remove any apparently trifling disorder as quickly as possible. Supply- ing good food, fresh, pure air and warm clothing, and main- taining the activity of the skin are also important preventive measures. After the disease is established, much can be accom- plished by attention to the diet and general regimen. In regulating the diet, it is necessary to take into consideration the catarrhal state of the intestinal mucous membrane usually present, and the almost useless condition of, at least, a number of the mesenteric glands, and to select those articles which are absorbed in the stomach or taken di- rectly into the blood vessels, without the intermediate action of the lacteals and mesenteric glands. The food must be sufficient to maintain the general strength, but not so abundant as to overtax the process of digestion. The following may be taken as an average daily schedule of both diet and regimen for a child of four years, in whom there is no excessive wasting or weakness : — On waking in the morning, say at 7 a.m., a thin slice of dry, stale bread, and three fluidounces of hot veal broth. At 8.30 a.m. a cold bath, given in this manner : — being CASEOUS DEGENERATION OF MESENTERIC GLANDS. 273 taken from bed, the whole body is briskly shampooed with a soft towel until the surface is aglow. The child is next made to stand in a tub sufficiently filled with hot water to cover his feet and ankles, and two gallons of cold water, containing an ounce of sea-salt or concentrated sea-water, are slowly poured over his shoulders. The skin is then thoroughly dried and rubbed until reaction is established; the child is wrapped in a blanket and put back to bed for half an hour. On rising, the abdomen should be com- pletely enveloped in a flannel binder, and the body clad in woolen underclothing from head to foot. At 9.30 a.m., breakfast. — A soft-boiled egg and two slices of stale bread. From 10.30 a.m. to 12 m. — A walk or romp in the open air, in good weather. At 12 m., lunch. — Half a dozen raw oysters or a bit of sweetbread or fish, and a slice of dry, stale bread. At 3 p.m., dinner. — Six fluidounces of beef, mutton or chicken broth ; a bit of minced roast beef, beef-steak, roast mutton, chicken, or wild fowl. A moderate quantity of spinach, stewed celery, boiled cauliflower, or other non- farinaceous vegetable, and one or two slices of dry, stale bread. No dessert except junket occasionally. At 7 p.m., supper. — Same as lunch, alternating the fish, sweetbread or oysters. Nothing should be taken for drink but filtered water or, better still, good spring water.* When there is much emaciation and weakness, the morn- ing bath must be omitted or substituted by a simple warm sponging; and some stimulant, as a teaspoonful of old whiskey, should be given three times daily. Diarrhoea demands an exclusive liquid diet, and it is * Directions for Philadelphia. 18 274 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. advisable to artificially digest the meat broths and milk, which must form the basis of this. The most useful drugs are cod-liver oil and the syrup of the iodide of iron, since the indications are to build up the general health and restore the glands to a healthy condi- tion. The former can be given as an emulsion with lacto- phosphate of lime in two- drachm doses three times daily, after eating, at the age of four years ; the latter in fifteen drop doses after meals. Often it is well to administer both preparations together. Locally, some good may result from the daily inunction of a weak mercurial or iodine ointment, for example : — R. Ung. Iodin. Comp., sjij. Ung. Belladonnas, ^j. Ung. Aquce Rosse, 3 v. M. R. Ung. Hydrargyri, giij. Adipis, gv. M. Of either a piece as large as a cherry may be rubbed into the skin over the tumor once every day. Other remedies are, of course, required to arrest diar- rhoea, or to relieve the different complications that may arise. Should the circumstances of the patient permit, change of residence to some locality having an equable climate, a bracing atmosphere and a dry, porous soil, will greatly assist in effecting a cure. CHAPTER IV. AFFECTIONS OF THE LIVER. Hepatic diseases do not occur so frequently during childhood as in adult life. Fatty and amyloid changes are the most common affections ; syphilitic disease, cirrhosis, tubercular deposit and parenchymatous inflammation stand next in the order named ; while echinococcus is very rare, and cancer almost unknown. Jaundice, on the contrary, is often met with, but this condition, though a complex and striking one, is simply an indication of disease of the vis- cus itself, or of its excretory duct. Congestion of the organ is also common. i. JAUNDICE. Icterus, irrespective of the age at which it occurs, is characterized by yellowness of the skin and conjunctivae, clay-colored stools and yellow-brown urine. During the first few days of life, especially after a difficult and tedious birth, there is apt to be intense congestion of the skin, followed, as the redness fades, by a brownish-yellow discol- oration. This appears on the second or third day, and disappears by the tenth. It is not jaundice, for it is entirely independent of liver disorder, and there is no yellowness of the conjunctivae, and no alteration in the faeces or urine. A form of true jaundice, however, does occur in the newly-born, termed icterus neonatorum, which may be studied before describ- ing the condition as it is seen in later childhood. 275 276 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. ICTERUS NEONATORUM. Both mild and dangerous types of this variety of jaun- dice are met with. The mild type occurs in infants prematurely born, or weak from other causes ; in those early exposed to the depres- sing action of cold, dampness, and foul air, and particularly in those who are born partly asphyxiated after tedious labor. It is difficult to understand the exact method in which these causes act. Cold undoubtedly produces catarrh of the duodenal mucous membrane, and plugging of the bile-duct by mucus ; the others, the last especially, act, in all probability, by altering the hepatic circulation. At birth there is a sudden transference of the blood-supply from the umbilical to the portal vein ; a change — according to Frerichs — temporarily followed by comparative emptiness of the blood vessels of the liver ; a diminution of vascular tension, and the passage of bile into the blood. Weber attributes the jaundice to pressure from congestion and oedema, the result of an arrest of the circulation in the umbilical vein before the establishment of respiration ; con- ditions present in infants born semi-asphyxiated. Birch- Hirschfeld has demonstrated that a dense areolar sheath surrounds the vessels in the notch of the liver and extends into the viscus along with the portal vein; this becomes cedematous and greatly swollen when there is venous ob- struction in the liver during difficult parturition, and, by pressure, obstructs the flow of bile into the intestine. The grade of jaundice in this type varies considerably. Sometimes the yellow discoloration is confined to the face, chest and back; the conjunctivae are but lightly tinged; the urine and faeces are unaltered, and after three or four days the trouble is at an end. In other cases, the yellow- ness extends to the abdomen and arms ; the conjunctivae AFFECTIONS OF THE LIVER. 2J*] are distinctly yellow ; the urine is dark and stains the diapers, but the stools still retain their natural color — golden yellow; the duration is about seven days. The best developed instances present universal and moderately deep discoloration of the skin; the conjunctivae are very yellow; the urine brownish, and the stools clay-colored. With this degree of jaundice, there is malaise, loss of appe- tite, constipation, and enlargement of the liver ; the lower edge of the right lobe often extending below the costal border as far as the umbilicus. Occasionally, instead of constipation, there is diarrhoea, with moderate heat and tenderness of the belly, and a quick pulse, indicating severe intestinal catarrh. These cases recover after a fortnight or more, though occasionally diarrhoea arising and persisting in a feeble infant, is suffi- cient to determine a fatal issue. The Treatment is simple. The infant must be kept in a warm, well-ventilated room ; the activity of the skin must be maintained by bathing, and chilling prevented by proper clothing. Constipation is to be relieved by fifteen or twenty drops of castor-oil, a soap suppository or an enema, and, if the skin be slow in resuming its normal color, it is well to prescribe an alkali, as : — J& . Sodii Bicarbonatis, gr. xxxij. Aq. Menth. Pip., Syrupi, aaf^ss. Aquae, q. s. ad f^ij. M. S. — One teaspoonful three times daily. The grave type depends upon congenital malformation of the bile-ducts and gall-bladder; compression of the bile- ducts by syphilitic inflammation and growths, and umbilical arteritis and phlebitis. a. Congenital malformation is rare, but when it occurs is 278 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. liable to affect several members of the same family in suc- cession; boys suffer twice as often as girls. There are a number of varieties : thus, the gall-duct may be converted into a fibrous cord; the ductus communis may be contracted, obliterated or absent; the gall-bladder may be rudimentary and the ducts absent; or all the ducts may be wanting. Whatever the condition, the result is enlargement of the liver with cirrhotic change, more or less marked in propor- tion to the duration of life. The organ is dark green or almost black in color, feels unnaturally firm to the touch, and under the microscope shows an excess of connective tissue. From one to two weeks after birth the retained bile begins to give rise to jaundice ; this appears as a slight yellowness of the skin, and steadily grows more distinct, though it varies considerably in intensity from day to day; at the same time, the conjunctivae are stained and the urine dark colored. After a day or two, the liver begins to encroach upon the abdominal cavity and rapidly enlarges; the spleen, too, increases in size, and these two lesions, together with flatulent distension of the bowels and occasional ascites, produce decided prominence of the belly. In spite of a uniformly good appetite, there is constant wasting. The bowels act sluggishly, the faeces are offensive, clay colored or dark green, from the presence of altered blood, and dilated haemorrhoidal veins can often be seen by inspecting the anus. Another frequent symptom is oozing of blood, either arterial or venous, from the umbilicus. This hemor- rhage is capillary in nature, and usually begins at night, and soon after the fall of the navel string ; an event that occurs between the fifth and ninth day. It may be com- bined with bleeding from the nose, mouth, stomach or bowels, and is exhausting and always difficult to control. AFFECTIONS OF THE LIVER. 279 This form of jaundice ends in death. When umbilical hemorrhage occurs, the course is short, varying from a few hours to six or seven days; in other cases, life may be prolonged as many months, and death result from some intercurrent disease. In the latter class, the secreting ele- ments of the liver are so far crippled by the constantly progressing cirrhosis that little bile is found, and the yel- lowness of the surface fades, or almost entirely disappears, before life ends. b. Syphilitic inflammation of the liver with its lesions and symptoms will be referred to in another place (see page 291). c. Inflammation of the umbilical blood vessels is due to blood poisoning. The infecting material in the infant is apparently identical with that producing puerperal fever in the mother, and is possibly caused by bacteria, as two forms of these — spherical and rod-shaped — have been discovered in the blood of infants so affected. In consequence, the liver undergoes marked degenerative changes ; the connec- tive tissue about the portal vein and its branches becomes swollen and presses upon the bile-ducts, and from this, as well as from alterations in the crasis of the blood, jaundice results. Discoloration of the skin makes its appearance a few days after birth and rapidly increases ; the urine is very dark, and the stools are scanty and passed at long intervals. The face is livid and pinched; the hands and feet are purple ; petechias appear under the skin ; the abdomen is distended by flatus and by enlargement of the liver and spleen ; there is tender- ness with fluctuation on palpation, and blood or bloody pus exudes from the umbilicus. The tongue is dry, there is little appetite, and the stomach rejects what food is taken, together with quantities of greenish mucus. Pyrexia is 280 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. noticeable from the beginning, and becomes more marked as the disease progresses ; the pulse is quick and the breathing hurried. The course is always short, and the invariably fatal ter- mination may be preceded by convulsions and coma. Treatment in either variety is most unsatisfactory ; little can be done beyond the employment of measures to main- tain the vital forces as long as possible. Umbilical hemor- rhage may be arrested by the application of Monsell's solu- tion, or, if this fail, by inserting two hair-lip pins through the skin at the root of the navel and twisting a ligature tightly around them in the form of a figure of eight. Syphilitic inflammation demands appropriate constitu- tional remedies, and in pyaemic cases the abdominal ten- derness must be relieved by warm fomentations and seda- tive applications. ICTERUS IN OLDER CHILDREN. Jaundice in late infancy and childhood usually depends upon catarrh, extending from the mucous membrane of the duodenum into the ductus communis; sometimes it is due to plugging of the duct by inspissated bile; and, again, to occlusion by the entrance of a lumbricoid worm. Certain structural lesions of the liver, poisoning by phosphorus and miasmatic influences, also produce it. Catarrhal jaundice — the only form necessary to consider in this connection — presents the features so common to, and so characteristic of, the same condition in adults. Briefly stated, there is more or less yellow or brownish-yellow dis- coloration of the skin, with troublesome itching, yellowness of the conjunctivae, porter-like urine, and clay-colored stools, devoid of the natural faecal odor. Other symptoms are anorexia, craving for acid drinks, a yellow-furred tongue, AFFECTIONS OF THE LIVER. 28 1 disordered digestion, listlessness, slowness of the pulse, slight reduction of the surface temperature, and disturbed sleep. The liver may be somewhat enlarged, projecting two inches or more below the costal border, and tender, or even pain- ful, on pressure. The result is always favorable, and the duration rarely longer than two or three weeks. Treatment. — Warm clothing, daily bathing followed by gentle friction to promote the activity of the skin, and a diet based on the same plan as for intestinal catarrh, are the first requisites. The medicinal treatment can be begun by a moderate dose of calomel, followed by a saline ; but if a laxative be required later, the drugs that stimulate the secretion of the liver and act upon the upper bowel must be excluded, and those selected which affect the lower segment, as aloes and castor-oil. Duodenal catarrh — the causal factor — is most speedily re- moved by alkalies. Four fluidounces of some saline water, as Kisssingen or Vichy, should be drunk at each meal, and the following mixture taken : — R. Ammonii Chloridi, gij. Aq. Menth. Pip., . . . . f|iij. M. S. — One teaspoonful, diluted, three times daily after meals, for a child six years old. Nux vomica is also useful, and two or three drops of the tincture may be administered thrice daily before eating. 2. CONGESTION OF THE LIVER. Congestion of the liver is quite common, especially in children of four years of age and upward. 282 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. Morbid Anatomy. — There is an increase in the size, weight and density of the organ, and its peritoneum is tense and shining. On incision, blood flows freely, and the section presents a mottled or " nutmeg " appearance, partly from dilatation of the intra-lobular veins and partly from staining of the cells by retained bile. In long-standing cases, those due to cardiac disease, for example, the cells in immediate proximity to the dilated intra-lobular veins atrophy ; those near them are stained with bile, and those most distant undergo fatty degeneration. In time the atrophied cells disappear ; their place is taken by connective tissue, which shrinks and produces a cirrhotic condition, the surface of the liver becoming granular and the cap- sule thickened. Etiology. — Even in health the amount of blood in the hepatic vessels varies from time to time, and there is always a temporary increase during the process of digestion. This normal hyperemia readily becomes abnormal and continu- ous when there is habitual over-feeding ; when the food is highly spiced and too stimulating ; and when insufficient exercise is taken. Congestion is often produced by chills, whether resulting from exposure to cold or from the poison of malarial fever, since, in either case, the blood is driven from the surface to the interior of the body. Again, car- diac disease, by obstructing the return of blood from the lung and overfilling the vena cava and portal vein, is an active cause. Symptoms. — The skin is sallow, or together with the conjunctivae distinctly jaundiced. There is malaise ; head- ache ; a yellow, furred tongue ; anorexia ; nausea ; relaxed bowels with clay-colored, offensive stools, and dark-colored urine loaded with lithates. Pain in the right hypochon- drium is usually present, and, as this is increased by turn- AFFECTIONS OF THE LIVER. 283 ing upon either side, the patient maintains a dorsal posi- tion ; there is also tenderness in this region, and the suf- fering is increased by coughing or deep breathing. On palpation, the right lobe of the liver can be detected, ex- tending two or three inches beyond the costal border, while at its edge is felt the gall-bladder distended into a pyriform tumor of variable size. At the same time the upper limit of percussion dulness begins in the third interspace, or at the level of the third rib, instead of the fourth interspace, as in health. Should the congestion depend upon heart disease, albu- minuria and oedema of the feet and legs are associated. Diagnosis. — Many instances of disordered digestion, with the expulsion of putty-like, undigested material from the bowels, are attributed to congestion of the liver, when in reality the gastro-intestinal tract alone is at fault. Such a mistake can be avoided, if it be remembered that to estab- lish the existence of the hepatic disease it is necessary to have enlargement of the organ, with pain and tenderness ; jaundice and clay-colored, offensive stools ; combined with disturbance of the functions of the stomach and intestines. Extension of the liver a finger's-breadth or more, below the costal border, does not absolutely indicate enlargement, since this often occurs without disease, in short-chested children, and in those whose chests are contracted and deeply grooved by rickets. Downward displacement and apparent enlargement may also be caused by pleuritic and pericardial effusions, and by emphysema of the lungs. On the other hand, an enlarged liver may be completely under cover of the ribs, for, in addition to being normally high in the thorax, it may be pushed upon by a collection of fluid or a growth in the abdominal cavity, or drawn up through the shrinking of a collapsed or indurated lung. It is 284 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. essential, therefore, to fix the position of the upper limit by percussion, as well as the lower edge by palpation, before forming a conclusion. Prognosis. — The course of the affection is short, and there is no danger unless the child be greatly reduced by previous ill-health, or there be cardiac disease. In the latter case, the duration and result correspond to, and de- pend upon, the gravity of the heart lesion. Treatment. — The child may be put to bed, or, if not ill enough to be so confined, should be kept within doors. The abdomen must be protected by a flannel binder or a layer of cotton batting covered with oiled silk, and the skin kept active by a daily warm bath, administered, in walk- ing cases, just before retiring to bed. Too much food of any kind is bad ; meat and highly-seasoned dishes are to be excluded from the diet ; and it is best not to extend the list beyond milk, mutton or veal broth, fish, bread and plain light puddings, as rice and milk. In the beginning, a child of six or eight years should get the following powder : — R . Hydrargyri Chlorid. Mit., gr. ij. Pulv. Ipecacuanhas, gr. ss. Sacchari, gr. v. M. et ft. chart. No. j. S. — To be taken in the evening and followed, next morning, by a teaspoonful of magnesia. Subsequently, five grains of chloride of ammonium should be given after food, and a small tumbler (five fluidounces) of Vichy taken with each meal. Aloes and the salines are the best remedies to relieve constipation during the course of the attack. In cardiac case, treatment must be directed chiefly to the heart; and in those due to malarial poisoning, antiperiodics are of little avail until the hepatic congestion is relieved. AFFECTIONS OF THE LIVER. 285 When convalescence is established, regular exercise in the open air must be insisted upon and a plain diet main- tained. Change of air is often most useful to break up the " bilious habit." 3. FATTY LIVER. This condition presents itself in two distinct forms, namely, fatty infiltration and fatty degeneration. FATTY INFILTRATION. In fatty infiltration, the quantity of fat in the hepatic cells is greatly increased without any alteration in the walls of the cells. Morbid Anatomy. — The liver is increased in all its dimensions, its surface is yellowish and oily, its margins rounded and its texture doughy. On section, the cut sur- face is distinctly yellow, mottled with brownish-red spots, and if a bit be put under the microscope, abundant granules and globules of fat are seen. Etiology. — One cause of fatty infiltration is an excess of farinaceous food. Then the deposition is physiological and transitory, the excess of hydrocarbons supplied from without being deposited in the liver in the form of fat. The second cause is chronic, exhausting disease, such as tubercle, scrof- ula, rickets, caries of bone, intestinal catarrh and syphilis. Here the fat is absorbed from the subcutaneous and other fat-containing tissues of the body. Symptoms. — It is only in well-marked cases that these are developed. An increase in the bulk of the liver with a rounded, inferior margin may be detected by percussion and palpation ; but this is frequently impossible on account of 286 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. the tendency the organ has, from its softness, to fall away from the chest-wall. There is a sense of weight in the right hypochondriac region and disturbed gastro-intestinal func- tion, due to portal obstruction. Jaundice and ascites are absent, and there is neither pain nor tenderness over the viscus. The Diagnosis is not difficult when enlargement, softness and blunting of the edge of the viscus can be detected by examination. The Prognosis depends upon the cause rather than the degree of change; occurring in the course of a protracted, wasting disease, fatty infiltration shows dangerous impair- ment of nutrition. Treatment. — Beyond a rigid exclusion of farinaceous and fatty foods from the dietary, all remedies must be directed to the relief of the originating disease. FATTY DEGENERATION. Fatty degeneration is a much rarer lesion in children than fatty infiltration. Morbid Anatomy. — The liver appears normal to the unassisted eye, but with the aid of the microscope the cells are found to be filled with minute protein or fatty granules, and tend to fragmentation and destruction. The whole, or only isolated portions of the viscus, may be changed in this way. Etiology. — The lesion is produced by acute affections, as measles, variola, scarlatina and typhoid fever; by chronic, exhausting diseases, as tubercle, scrofula and rickets; and by accidental poisoning with arsenic or phosphorus. There are no characteristic symptoms, the result is inva- riably unfavorable, and no special indications for treatment are presented. AFFECTIONS OF THE LIVER. 287 4. AMYLOID LIVER. This lesion is moderately common in childhood, and usually occurs as a factor of general amyloid degeneration. Morbid Anatomy. — The disease consists in a more or less complete infiltration of the cells by a peculiar trans- lucent, refracting substance, possessing the property of fix- ing iodine and assuming a mahogany-brown color, which, on the application of sulphuric acid, changes to green, blue, violet or red. The infiltration begins in the hepatic arterioles and capillaries, and at first is limited to the middle zone of the lobules ; thence it extends to the periphery and centre, destroying the normal elements of the cells and converting them into irregularly shaped, glassy-looking blocks. Fatty infiltration is often associated. Uniform enlargement; in- creased density; yellowish-gray color; smooth, shining peri- toneum; thin edges, and the exposure, on section, of dry, homogeneous, glistening surfaces, are the gross charac- teristics. The spleen, kidneys and lymphatic glands are often simi- larly altered, and sometimes the mucous membrane of the stomach and intestines. Etiology. — Amyloid degeneration of the liver is always produced by some chronic disease, attended by suppuration and purulent discharge. Empyema with a fistulous opening in the chest-wall ; dilated bronchi with copious muco-puru- lent expectoration ; scrofulous abscess ; chronic pulmonary tuberculosis ; suppurative diseases of the bones and joints, and constitutional syphilis, are the most frequent causes. It occurs at any age, but is more frequent after the fifth year, and in boys than girls. Symptoms. — There are few rational symptoms other than those belonging to the originating disease. Tenderness and pain in the hepatic region are absent, and so, too, are 288 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. jaundice, distension of the superficial abdominal veins and ascites ; except the glands in the fissure of the liver be coin- cidently enlarged by waxy deposit, when, from pressure upon the portal vein and bile-ducts, the last three phenomena may be developed. The patient complains of weight, discom- fort in the right hypochondrium, and is weak, wasted and anaemic, with pale, sallow skin, clubbed fingers and cedema- tous feet and ankles. When the kidneys are involved, the urine is increased in quantity, has a low specific gravity (about 1014), is pale, lemon colored, and contains albumen, and, at times, hyaline tube casts. Dropsy of the extremities is due in great part to this complication. If the stomach and intestines be implicated, there is a tendency to vomit- ing and diarrhoea. Physical examination yields very characteristic signs. The abdomen is prominent, especially over the upper third, and both percussion and palpation show that the liver is greatly and uniformly enlarged. The upper margin of dul- ness is higher, by an inch or more, than normal ; while the lower edge of the right lobe, somewhat blunted, but per- fectly well defined, can often be felt as low down as the level of the umbilicus. The portion uncovered by the ribs feels very dense and firm, and perfectly smooth, except where broken by the natural fissures. The spleen can often be detected projecting as a hard mass . from beneath the left costal border. The absence of enlargement, however, is no proof against the existence of amyloid change in the organ; in about half the cases there is no alteration in size. In course, the disease is always slow. Diagnosis. — This is readily made from the physical signs furnished by the liver and spleen ; the absence of jaundice and ascites ; the previous history of cachexia and suppura- AFFECTIONS OF THE LIVER. 289 tion ; the character of the urine ; the anaemia, and the gastro- intestinal symptoms. . Congestion of the liver with consequent enlargement has a different clinical history, rarely occurring in cachectic or anaemic cases. A fatty liver, while large, is soft and yield- ing to the touch, and is unattended by increase in the size of the spleen or albuminuria. Prognosis. — The prospect of ultimate recovery is better in children than in adults, for, provided the cause of the degeneration can be removed, it is quite possible for the liver to return to its natural dimensions and to an apparently healthy condition, through the active reparative power always present in early life. Nevertheless, amyloid change in the liver adds greatly to the danger of the originating disease, and is fatal in most cases. Treatment. — It is almost needless to state that atten- tion must first be given to the removal or amelioration of the cause. It is much more difficult to cure the disease when once developed, than to prevent it by checking chronic suppuration, removing carious bone, healing diseased joints, energetically treating constitu- tional syphilis, and building up the health in cachectic subjects. To combat the disease itself, the diet must be as nu- tritious as the activity of digestion will permit ; a moderate quantity of alcoholic stimulants must be taken daily; the child must be properly clothed, to prevent chilling, and must live as much as possible in the sun- light and open air, or, if confined to the house, in a light, airy room. Alkalies, iron and iodine are the most useful drugs. Of alkalies, chloride of ammonium is the best, and it may be given in combination with a bitter, as : — 19 29O DISEASES OF DIGESTIVE ORGANS IN CHILDREN. R . Ammonii Chloridi, 3 ij. Inf. Gentianae Comp., f^> u j- M. S. — One teaspoonful four times daily at the age of six years. It is often well to combine iron with the ammonia salt, for example : — R. Tr. Ferri Chloridi, f^j. Ammonii Chloridi, ^ij. Inf. Calumbse, '. . . q. s. ad f !§ iij. M. S. — One teaspoonful three times daily. Another good way of administering iron is in the form of a modified Basham's mixture : — R. Tr. Ferri Chloridi, f£J. Acid. Acetici dil , f ^ jss. Liq. Ammonii Acetatis, f 3 x. Elix. Aurantii, f, 5 ) v » Sympi f|j. Aquas, q. s. ad f^yj. M. S. — One tablespoonful four times a day. This formula is particularly useful when there is kidney complication with oedema. Iodine is most efficient if there be a syphilitic taint, it may be given in the form of iodide of potassium, five grains or more three times a day, with a bitter infusion ; or liquor iodinii comp. can be employed in doses of two drops, well diluted, thrice daily. Complications must be met as they arise. Vomiting, by ice, cold Apollinaris water, bismuth, and counter-irritation to the epigastrium ; diarrhoea, by vegetable astringents, with small doses of opium ; and dropsy, by diaphoretics and diuretics. AFFECTIONS OF THE LIVER. 29 1 5. SYPHILITIC INFLAMMATION OF THE LIVER. Syphilitic hepatitis is frequently encountered in the newly-born, though rare in more advanced childhood. Morbid Anatomy. — The liver may be the seat of acute swelling, which, without showing marked gross alteration, is associated with a diffused growth of connective tissue elements ; again, there may be a localized gummatous change; and, finally, the inflammatory process may be confined to the septa — peripylephlebitis syphilitica. The proliferation of connective tissue takes place both between the hepatic islands and in their interior, thus differing from cirrhosis, where the increase is only between the lobules. When jaundice occurs, the small bile-ducts are thickened and occluded by epithelial cells, and the organ is enlarged, and brownish-yellow in color. Symptoms. — In mild cases these are few and unchar- acteristic ; in those that are grave there are jaundice, ascites, hemorrhage from the umbilicus and intestines, ecchymosis of the skin, subnormal temperature, rapid wasting, and often syphilitic lesions of the skin and mucous membranes. On abdominal exploration, the liver is found to be enlarged and hard, and the spleen increased in size. Diagnosis. — The early age, the history of an inherited taint, the association of enlargement of the liver with jaun- dice and ascites, make this a matter of little difficulty in cases that are at all marked. Prognosis is unfavorable, though the opinion must rest upon the degree of cachexia. Goodhart states that all of his cases proved remarkably amenable to mercurial treat- ment, but this does not correspond with the experience of other observers. 292 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. Should deep jaundice, ascites and hemorrhage occur, death is the almost invariable end. Treatment. — As in other syphilitic affections, mercurials must be followed by tonics. One-eighth of a grain of calo- mel, or one grain of mercury with chalk ; may be adminis- tered morning and evening, or ten grains of mercurial oint- ment may be rubbed into the skin once a day, either directly by the fingers of the nurse, or by being smeared upon the flannel binder. After the liver has been reduced in bulk and other mani- festations of the poison are under control, syrup of the iodide of iron, in two-drop doses three times daily, is the most efficient tonic. Iodide of potassium is also useful ; it acts best when combined with chloride of ammonium, as : — R . Potassii Iodidi, gr. xxiv. Ammonii Chloridi, gr. xxxvj. Syrup. Sarsaparillae Comp., f^ ss « Aqua?, q. s. ad f^iij. M. S. — Teaspoonful three times daily for an infant of one month. In those fortunate instances that yield to treatment, splenic enlargement disappears less rapidly than that of the liver, and requires the daily application of compound iodine ointment diluted in the proportion of one part to seven of lard. 6. CIRRHOSIS OF THE LIVER. In childhood, cirrhosis must be classed among the un- common diseases of the liver ; the fact of its occasional occurrence, however, has been abundantly proved by post- mortem examinations. AFFECTIONS OF THE LIVER. 293 Morbid Anatomy. — There are two forms, namely, the atrophic and the hypertrophic. In atrophic cirrhosis or hob-nailed liver, the organ is contracted and dense in texture, with nodulated surfaces, thin edges and thickened capsule ; on incision the cut sur- face is grayish-yellow in color, and traversed by a distinct fibrous network. The lesion begins as a chronic inflamma- tory condition of the branches of the portal vein, and consists of a rapid development of embryonic cells, with subsequent conversion into fibrous tissue. The new formed tissue follows the branches of the portal vein within the substance of the gland; extends into the inter-lobular spaces and forms meshes of variable size, but always em- braces several lobules. Some enlargement may attend the primary formation of embryonal tissue, but the shrink- ing of cicatricial contraction invariably follows; the cells become flattened and atrophied ; there is a marked reduc- tion in size, and the circulation in the hepatic portal vessels is greatly obstructed. The smaller bile-ducts are little affected, and blood for the nourishment of the organ and for the for- mation of bile is carried by vessels developed in the neoplasm. In hypertrophic or biliary cirrhosis, the liver is usually enlarged, perhaps to twice its normal dimensions. It has a smooth surface, a thin edge, and its section is orange-yellow or green. The fibroid growth begins around the in- tralobular branches of the bile-duct, and envelops and isolates separate lobules ; it follows the ramifications of the bile-ducts ; is more diffused than in the atrophic form, and denser and thicker in some portions than in others. The portal circulation is not necessarily embarrassed, but the biliary ducts are obstructed and dilated, and have their epithelial lining increased in thickness. In both forms there is enlargement of the spleen, and in 294 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. some cases there is an association of the characteristic lesions. Etiology. — The causes are, as yet, ill-determined. Al- coholic excess, the prime factor in adults, is, of course, inoperative in children, except in very rare cases ; some authorities, however, are inclined to look upon the intem- perance of parents as, at least, a predisposing element, and regard the vice of drunkenness as one of the sins of the fathers visited upon their offspring. Congenital de- ficiency of the bile-duct is always attended by cirrhosis. Constitutional syphilis frequently, and general tubercu- losis occasionally, precede it. It is not limited to any sex or age, though more frequent in boys than girls, and oftener met with between the sixth and twelfth years than at an earlier period of life. Symptoms. — Both forms are preceded, for a variable time, by the evidences of defective nutrition, but, as might be expected from the different pathological conditions, the after symptoms are dissimilar. With atrophic cirrhosis the child is peevish and restless, sleeps badly at night; has indi- gestion, flatulence and costive bowels ; a pale and pasty complexion, and dark circles about the eyes. His mus- cles grow flabby, there is general wasting, and the urine is thick with lithates, or is very acid and deposits a brick- dust sediment of uric acid. After these symptoms have been present for a period — usually a long one — pain in the region of the liver and ascites are developed. With the ascites there is prominence of the abdomen, dilatation of the superficial abdominal veins, and, at first, enlargement of both the liver and spleen. Soon the liver begins to de- crease in size, but the spleen continues to enlarge.* Weak- * If ascites be extreme, it is often difficult to detect the spleen by palpation when the patient is in the ordinary dorsal position, or on the right side. In such cases placing the patient upon the hands and knees entirely removes the difficulty. AFFECTIONS OF THE LIVER. 295 ness and loss of flesh are progressive ; the ascites becomes more marked ; there is oedema of the feet and legs ; the skin is sallow, and harsh to the touch; the tongue is coated ; the appetite impaired ; the stomach irritable ; the bowels alternately confined and relaxed ; there is abdominal pain ; hemorrhoidal swellings are noticeable ; hemorrhages occur from the stomach, bowels, nose and gums, and pete- chial spots appear beneath the skin. The course is prolonged and interrupted by periods of apparent improvement, during which the ascites diminishes and the patient is free from discomfort, and in some degree recovers health and spirits. General dropsy, severe diarrhoea or hemorrhages indi- cate that the end is near. Sometimes intercurrent inflam- mation of the pleura or lungs is the direct cause of death. In hypertrophic cirrhosis, the skin, conjunctivae and urine are deeply stained by bile, and the stools, which vary greatly in number and consistency, are clay-colored. The liver and spleen are enlarged, but there is no distension of the superficial abdominal veins, and no ascites. At times the jaundice and enlargement of the liver increase rapidly ; then there is moderate fever with much pain in the right hypochondrium. As the end approaches the pulse be- comes markedly irregular; the tongue grows dry and brown ; the teeth are covered with sordes ; there is com- plete anorexia; rapid wasting; bleeding from the gums, from the stomach or beneath the skin ; apyrexia, drowsi- ness, stupor, and, finally, convulsions. The course is more rapid than in the former variety, but still protracted. Should both forms exist together, there is a combination of jaundice, ascites and distension of the veins in the abdomi- nal wall. 296 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. Diagnosis. — The characteristic features of atrophic cir- rhosis are diminution in the area of liver dulness, follow- ing a temporary increase in the bulk of the organ ; enlargement of the spleen ; dilatation of the superficial veins ; ascites ; hemorrhoids ; a dry, earthy skin, and gas- trointestinal hemorrhages, occurring, without fever, in a child who has a history of prolonged ill-health, feebleness and wasting. The second and more uncommon variety, while having very much the same preliminary history, presents as its distinguishing marks enlargement of the liver and spleen without ascites; jaundice, with fever; pain in the hepatic region ; and, subsequently, malignant jaundice, with ty- phoid symptoms, rapid wasting, coma and convulsions. Acute yellow atrophy, which has many of the symptoms of the final stage of biliary cirrhosis, is distinguished by its abrupt onset and rapid course, and is among the rarest of diseases in children. Prognosis. — The result is almost invariably unfavorable, and it is only under the most fortunate conditions that even a temporary improvement can be obtained. Treatment. — Before a diagnosis is established, and while the patient is merely suffering from ill-defined symptoms of bad health, with imperfect digestion, hygienic and thera- peutic measures are to be directed to the restoration and preservation of the general strength, and to correcting any disorder of the organic functions. When the hepatic affection declares itself, an alkaline or a purely tonic treatment may be adopted. Alkalies are indicated when the hepatic and gastro-intestinal symptoms are in excess of the wasting and general debility; tonics under opposite circumstances. In the former case, the following prescription is useful : — AFFECTIONS OF THE LIVER. 297 R. Sodii Bicarb., ^ij. Tr. Nucis Vom., n\xviij. Inf. Calumbse, q. s. ad f^iij. M. S.^— Two teaspoonfuls three times daily, for a child of ten years. In the latter, Basham's mixture may be employed, or a combination of iron and quinine, as : — R. Quiniee Sulph., gr. xij. Tr. Ferri Chloridi, f jjj. Syr. Zingib., f gj. Aquae, q. s. ad f Sj iij. M. S. — Two teaspoonfuls three times daily. Both plans must be followed out steadily and continu- ously, to obtain any beneficial results. To relieve constipation, from two to four fluidounces of Hunyadi water should be taken every morning on an empty stomach. Diarrhoea can be controlled by sub-carbonate of bismuth, and hemorrhage by gallic acid or aromatic sul- phuric acid. It is important to order a liberal diet — milk, eggs, meat and farinaceous foods in full proportion to the capacity of digestion. As in other diseases of the liver, the skin must be kept active by daily warm baths, and chilling prevented by flannel under-clothing. If ascites be so great as to impede the action of the dia- phragm, paracentesis must be resorted to at once. A fine trocar or one of Southey's tubes may be used.* The opera- tion should be repeated so soon, and as often, as reaccumu- lation renders it necessary. When performed early enough, it sometimes has, as in adults, more than a merely palliative effect. * See section on Ascites. 298 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. 7. SUPPURATIVE HEPATITIS. Abscess of the liver is an extremely uncommon disease in children. The only case that has ever come under my notice, presented the following clinical history: — George , set. 5 years, was first brought to the Dispen- sary of the Children's Hospital on April 27th, 1875, during the service of Dr. George S. Gerhard. Though residing in a malarious locality, and in a poor and filthily-kept house, he had always had good health up to one week previous to the above date, when he began to complain of pain in the region of the umbilicus. Under appropriate treatment he passed several lumbricoid worms, and the pain disappeared. A week later, however, it returned, and as his bowels were constipated, his father administered a tablespoonful of castor- oil; this produced a free evacuation, containing from twenty to thirty lumbrici, many being of large size. After this he seemed to be perfectly well until May 9th, when the pain in the abdomen reappeared; he now began to lose his appe- tite, and a swelling was noticed in the right hypochondriac region. When I saw him first, on May 15th, his general appearance was good ; his cheeks having a healthy color, and his body being sufficiently stout. His tongue was lightly coated, and his father stated that his appetite was poor, and that, though his bowels were moved daily, the passages were small. There was no heat of skin or jaundice, the pulse and respi- ratory movements were normal in frequency ; he had no cough, and, on physical examination, no pulmonary or car- diac affection could be detected. His abdomen was tym- panitic, the whole of its upper third was tender to the touch, and in the upper part of the right hypochondrium there was an oval tumor, about as large as a turkey's egg, having its long diameter directed transversely, and projecting at its AFFECTIONS OF THE LIVER. 299 most prominent part nearly an inch from the surface of the abdomen. The skin covering this tumor was somewhat cedematous, but was freely movable, and natural in color and temperature, while the tumor itself was hard, tender, completely immovable, and the seat of neither fluctuation nor pulsation. It was surrounded by an area of induration, the boundary of which could not be accurately ascertained on account of the pain produced by palpation, though it appeared to extend from the costal border to the lower third of the right hypochondriac region, and from the median line of the abdomen to the right side. The right hypochondrium was dull, except just below the margin of the ribs, where there was slight, probably trans- mitted, tympanitic resonance, detected only by deep per- cussion. The liver dulness began in the ordinary position above, and, on light percussion, was continuous below with that in the hypochondriac region. The patient did not complain of pain except when the swelling was touched, or when the whole body was jarred, as in walking down stairs. On a level surface he was able to walk easily. No history of an injury could be obtained, but on careful questioning it was discovered that throughout the winter he had " coasted " a great deal on his sled, and always rode "belly-bumpers." He was ordered to be kept quiet, and to have a liquid diet, with poultices over the abdomen, and a dose of castor-oil. May 1 6th. Had a large passage from the bowels, the evacuation being dark-colored and lumpy; during the night was restless and feverish. May 17th. Tongue somewhat cleaner and abdomen less tympanitic. The tumor was more prominent; there was deep-seated fluctuation, and the skin covering the mass was less cedematous, not so freely movable as before, and of a dusky-red hue. Patient walked with his body bent forward, 300 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. as if a more upright posture were painful. Prescribed f5ss of tine, cinchon. comp., three times daily, and an increased diet, at the same time directing his parents not to allow him to get out of bed, and to apply warm poultices continuously to the belly. May 19th. Visited him at his home, and found him en- tirely free from fever; his tongue was clean, his appetite had returned, and his bowels had been opened; the stool, which had been kept for inspection, was copious, well formed, and in every way natural. The induration around the tumor, or more properly the abscess, for such it now appeared to be, had extended so as to fill nearly all of the right hypo- chondrium, being almost five inches in transverse diameter. There was well-marked fluctuation, and the skin investing the abscess was tightly adherent over a space about four inches in circumference. The abdominal respiratory move- ments were restricted, and any effort at full inspiration caused pain. There was no sensation of throbbing in the abscess, and the patient seemed to be perfectly comfortable as long as he remained quiet. The abdomen was moderately dis- tended. May 2 2d. No change, except that the fluctuation was more superficial, and the integument adherent over a large surface. The former treatment was continued, and as the pulse was more frequent than before, and as he was pale and . languid, a teaspoonful of brandy thrice daily and full diet were ordered. May 26th. Found him up and playing about as if nothing was the matter. Having him stripped and placed in bed, the following observations were made : Abscess more prominent than at last note, but more localized ; in its centre there is very superficial fluctuation, extending over an area an inch and a half in diameter and bounded by a firm margin. The AFFECTIONS OF THE LIVER. 301 skin covering this space is dark red in color, feels very thin, almost as if it could be broken by the pressure of the finger, and is somewhat hotter than the surrounding integument. About the abscess there is a mass of induration which does not project beyond the level of the rest of the abdomen, but which extends from the lower border of the ribs to the middle of the right lumbar region, and from the mid-line of the abdomen to the right side; its outline is semicircular, the edge being smooth and well defined, so much so that the fingers can be inserted beneath it. The skin is adher- ent over the whole mass, but most so immediately around the position of fluctuation. Both palpation and percussion indicate that it is connected with the right lobe of the liver. There is some pain excited by palpation, though this is much less than formerly. There is no jaundice. No change was made in the treatment. May 29th. The abscess was more circumscribed, being about the size of an English walnut, and the pus was still nearer to the surface. As it was impossible to keep the patient quiet, and fearing lest he might rupture the abscess in his play, aspiration was determined upon. Accordingly, a large aspirator needle was introduced to the depth of half an inch. About two drachms of thick, grumous pus, mixed with blood, escaped into the receiver, when the canula be- came plugged, and no more could be withdrawn.* A poul- tice was applied, and the patient ordered to remain in bed during the rest of the day. The operation was followed by no bad symptoms, and the next day he was up, amusing him- self as before. There was, however, considerable discharge of thick pus from the opening left by the aspirator needle. * A microscopical examination of a portion of this material revealed pus cells, compound granu e cells, blood corpuscles, and numerous polygonal cells having well-defined nuclei and resembling liver cells. 302 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. June 1st. The wound made by the needle closed. Scarcely any fluctuation could be detected, and there was but little redness of the skin. On passing the finger over the position of the abscess a cup-shaped depression was felt, bordered by a well-defined edge of dense tissue. The induration was reduced ; its lower margin was still semicircular, and could be easily isolated, while the upper margin, on the other hand, could not be discovered, as the mass extended under the ribs. There was hardly any pain on manipulation, and the boy's general condition was very good. June 5th. There were no signs of the abscess, except a small spot of dusky redness, and slight retraction and puck- ering of the skin at the point of puncture ; in this situation, also, the integuments were adherent to the parts below. The induration was diminishing, and its edge, which could still be distinctly felt, was approaching the right costal border. All treatment was suspended. On October 30th, the child was in excellent health. The skin, for a short distance about the seat of puncture, was somewhat discolored and puckered, and was less freely movable than that of the remainder of the abdomen. Per- cussion and palpation showed that the right lobe of the liver was slightly contracted. In reviewing the preceding history, the question that naturally suggests itself is, whether the disease was hepatic abscess, or merely an abscess of the abdominal wall. In the early stage of the former affection, the general symptoms are similar to those observed in acute hepatitis ; jaundice being present only in exceptional instances, while the forma- tion of pus gives rise to rigors, frequency of the pulse, night sweats and fever, the latter often resembling the pyrexia of quotidian or tertian intermittents. The almost entire absence AFFECTIONS OF THE LIVER. 303 of constitutional disturbance in this case, however, is no argu- ment against the existence of hepatic abscess ; as it is gen- erally admitted that the symptoms are often very latent, and that in many instances no suspicion of an abscess has been entertained until its discovery by manual exploration, or by the discharge of pus in various directions, and sometimes even not until revealed by post-mortem examination. The local symptoms, on the contrary, were well marked ; thus there was localized, though extensive, enlargement of the right lobe of the liver, and toward the upper part of this enlargement there was an ill-defined, oblong tumor extending beyond the level of the abdomen. The skin covering this tumor was at first slightly cedematous, but perfectly movable and normal in color and temperature. From day to day, as the tumor became more circumscribed and approached nearer the surface, the hepatic enlargement increased, and conjointly with the appearance of fluctuation the oedema disappeared, the skin became dusky-red in hue, hotter than the surrounding integument, and adherent. There was also tenderness on pressure ; pain excited by deep inspiration or any jarring movement, and a peculiar bending forward of the body in walking. Again, after the opening of the abscess, all these symptoms subsided, and there was puckering of the skin and rapid reduction in the size of the liver ; its projecting margin remaining semi- circular, smooth, and well defined. Finally, there was slight contraction of the right lobe. There are two other points of importance, viz., the de- tection, by palpation, of a smooth edge of dense tissue bordering the area of fluctuation, which gave the impres- sion that the fluid was contained in a cup-shaped cavity in a solid organ, and the microscopical characters of the pus which was removed. 304 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. Now, all these symptoms are characteristic of an hepatic abscess, so situated on the convexity of the liver as to point toward the surface of the abdomen ; the adhesion of the integuments being, of course, due to local peritonitis. Abscesses of the abdominal wall, on the other hand, be- sides being superficial from the outset, have a different position, being usually seated in the rectus muscle or ad- joining connective tissue, and in the neighborhood of the umbilicus ; at the same time there is generally violent throbbing pain; the redness and tumefaction of the skin are earlier and better developed, and the constitutional symp- toms accompanying the formation of pus are more con- stantly observed than in abscess of the liver. The general management of circumscribed hepatitis, prior to the formation of pus — if the symptoms be such as to lead to a diagnosis at this time — simply requires careful regula- tion of the diet, rest, and attention to the various functions of the body, particularly that of the bowels ; for even if the existence of inflammation be ascertained, it is hardly probable that anything can be done to prevent suppuration. In relation to the propriety of evacuating hepatic ab- scesses, the bulk of authority is in favor of so doing, when they point externally so as to be detected by palpation, when firm adhesions have formed, and when the pus is near the surface. As to the method of evacuation, a free incision is perhaps preferable to puncture with an aspirator needle ; first, because the pus is often mingled with shreds of connective tissue and broken-down liver substance, liable to obstruct the needle and render it useless ; or, even if all the fluid be withdrawn, to remain and prolong the process of suppuration ; second, as the inelasticity of the walls of the cavity cannot prevent the entrance of air, it is much better to provide a free way of. exit, than to have AFFECTIONS OF THE LIVER. 305 the air confined, as it would likely be in the event of the small opening made by the needle becoming closed. For the purposes of exploration, however, the aspirator may be used with advantage. After being opened, the abscess is to be dressed in the ordinary manner, while strict rest should be enjoined, and tonic and supporting measures employed. Subsequently, nutritious diet and exercise in the open air, the latter adapted to the strength of the patient, are much more important than mere medication. Tuberculosis of the liver is sometimes associated with tubercular peritonitis, and is commonly encountered at the autopsies of children who have succumbed to acute general tuberculosis. In such cases the liver is anaemic, yellowish and small. Semi-transparent granules (miliary tubercles) are seen upon the capsule and detected by the micro- scope in the connective tissue that surrounds the branches of the portal vein; there is, too, an interstitial hepatitis, with the formation of embryonal and fibrous tissue. There are no definite ^symptoms, and a diagnosis is hardly possible without post-mortem section. Hydatid Disease and Cancer are so infrequent in child- hood, and when they do occur present so nearly the symp- toms of the same conditions in adults, that it is unnecessary to devote space to their consideration. 20 CHAPTER V. AFFECTIONS OF THE PERITONEUM. i. PERITONITIS. Children, like adults, are subject to attacks of inflamma- tion of the peritoneum. These may be primary or secondary in origin, acute or chronic in course, and general or local in distribution. The affection occurs at any age from birth to puberty, and there are indisputable evidences on record of its devel- oping during the later months of intra-uterine life. The primary or essential form is almost uniformly acute and general. Secondary peritonitis, on the contrary, may be either general or local, the inflammation often beginning in a limited area and gradually extending over the whole surface. It is also more common than the primary variety, and, while often acute, more frequently runs a chronic course. Morbid Anatomy. — In acute general peritonitis, the blood vessels of the sub-serous tissue of the peritoneum are engorged with blood, and the membrane is reddened, either generally or in patches ; mottled by isolated spots of ecchymosis, and opaque and thickened. Serum, some- times clear, sometimes mixed with pus and flakes of fibrin, fills the abdominal cavity ; or, again, the effusion may be purulent; in either case, it is most abundant in the pelvis and between the mesenteric folds. Acute local peritonitis occasions connective tissue hyper- 306 AFFECTIONS OF THE PERITONEUM. 307 plasia, omental and intestinal adhesions, and, at times, localized suppuration. Chronic general peritonitis gives rise to a sero-fibrinous exudate ; this may be sufficiently abundant to appear as a thick membrane, and in time may undergo fatty, caseous or calcareous degeneration. Chronic local peritonitis results in the formation of cir- cumscribed adhesions, membranous exudations of limited extent, and sacculated collections of pus. Etiology. — Fcetal peritonitis is caused by syphilis or some specific infection of the mother. During the first few- days of life it may be due to inflammation, suppuration or gangrene of the umbilicus ; to congenital occlusion of the anus ; or to infection from a mother ill with puerperal fever. Later in childhood, primary peritonitis arises from blows upon, or other injuries to the abdomen, and from sudden chilling of the body after violent exercise ; a number of cases having been noted in which the attack could be traced to the act of lying to rest, after an exciting or fa- tiguing game, prone upon damp ground. The secondary form may result from the escape of faecal matter into the abdominal cavity through a perforation of the intestine : — called perforative peritonitis. It may also occur during the course of one of the exanthemata, scarlatina especially — septic peritonitis. Finally, it may be occasioned by ex- tension of inflammation from some one of the abdominal viscera, or from the pleura ; in the last instance there may be an element of sepsis. Chronic peritonitis sometimes follows an acute attack but is most often an attendant of tuberculosis and presents the characters of chronicity from the outset. Symptoms. — In primary peritonitis, and in other cases of the acute general disease not due to perforation or sepsis, 308 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. the attack begins with more or less rigor, abdominal pain and vomiting. The pain is stinging or lancinating in char- acter, and is limited, at first, to one flank, to the supra- pubic region, or the neighborhood of the umbilicus, but soon becomes general ; it is increased by pressure or by any act calling the abdominal muscles into play, as deep breathing, sneezing, coughing and vomiting. The vomiting is frequent and very violent, producing so much distress and fatigue that after each effort the patient falls back on the pillow with pale, haggard, and sweat-bedewed face ; the material rejected consists, in the beginning, of partially digested food ; later, of bile-stained mucus. Fever quickly follows the shivering, and as soon as in- flammation is fully established, the axillary temperature may reach 104 F., although the usual range is from 101 to 102 . With the pyrexia there is a frequent, small, wiry pulse, and the breathing assumes the superior costal type ; in some cases (where there is a large effusion) growing hurried and difficult. The child ceases to move his legs, or takes to bed early and lies immovably upon his back, with the knees drawn up. The face is pale and anxious, the nose sharp and the nostrils thin and expanded. The abdomen is distended and passive, so far as respiratory movements are concerned ; palpation yields a certain sense of resistance, sometimes develops fluctuation,* and always excites intense pain; percussion elicits tympany over the upper anterior portion of the belly and dulness over the de- pendent parts, and on auscultation, friction sounds may be heard when there is a fibrinous exudation. * When fluctuation is indistinct, Duparcque recommends that the child be placed on one side for a few moments, so that the whole quantity of fluid may gravitate to the depending flank ; then quickly turned upon the back, when dulness and temporary fluctuation will be found at the site of accumu- lation. AFFECTIONS OF THE PERITONEUM. 3O9 The tongue is pointed, red at the tip and edges, and covered in the centre with a dry, moderately heavy, brown- white fur. There is anorexia and increased thirst. Con- stipation is the rule if the intestinal peritoneum be in- volved ; then, too, there are frequent attacks of severe griping pain ; on the other hand, there may be diarrhoea, with watery evacuations, if the inflammation be attended by oedema of the sub-mucosa with transudation of. serum into the bowel. The urine is high colored and somewhat reduced in quantity and, while ordinarily passed with freedom, is re- tained when the serous coat of the bladder is involved in the inflammation. Sleep is disturbed and restless ; in infants there may be convulsions ; in older children, delirium. During the course of the attack, which usually extends over a period of seven days, the strength steadily fails ; there is considerable loss of flesh, and the symptoms pres- ent at the onset continue unabated and unchanged. As death approaches vomiting usually stops, but the other symptoms become more and more grave. The patient lies in an apathetic condition, with sunken eyes and half-closed lids; his face is drawn and either pale or cyanosed; the tongue is dry, brown and pointed ; there is marked tym- panites and the pulse is extremely small and frequent. Occasionally this variety of acute peritonitis ends in re- covery ; the exuded fluid being either reabsorbed or spon- taneously evacuated through the umbilicus or abdominal wall.* In the first instance, the symptoms subside gradu- ally ; in the second, rapidly; though in both, the course is protracted ; the fistulous openings left after the discharge of pus rarely closing under four or five weeks. * M. Gauderon mentions ten such cases, eight of which recovered. 310 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. Perforative peritonitis requires separate description, since it has a set of symptoms entirely its own. It is the most common form of the disease in children, and in the ma- jority of cases results from rupture of the vermiform ap- pendix or caecum ; perforation of typhus or tubercular ulcers being exceptional in this class of patients. The attack begins suddenly with intense pain in the abdomen, quickly followed by profound collapse. The face soon becomes pale and haggard ; the eyes are deeply sunken, and the hands and feet cold, though the body heat is increased; the rectal temperature ranging to 103 or 104. Other features are great thirst, occasional vomiting, a dry, red and pointed tongue ; locked bowels ; a rapid, small, thready pulse ; thoracic respiration, often hurried and difficult, and suppression of urine. From the beginning the belly is greatly distended by gas escaping from the intestine ; the abdominal respiratory movements cease ; palpation is very painful, and percussion yields a uniformly drum-like tympany that extends high up under the ribs, and completely masks the liver dulness. Death almost invariably takes place either on the third or fourth day of illness, and is usually preceded by a few hours' freedom from suffering. While this is the ordinary course of perforative perito- nitis, it happens sometimes that the shock is so great that the patient neither feels pain nor complains of tenderness when the abdomen is touched, and there is a general latency in the symptoms. Again, extravasation being limited by preformed adhesions, the inflammatory action is circum- scribed, and the resulting abscess, by pointing and discharg- ing through the abdominal wall or into the intestine, may either end in recovery, or in the production of a permanent faecal fistula. AFFECTIONS OF THE PERITONEUM. 3II In septic peritonitis the symptoms are either inherently latent, or are masked by the collapse that follows the onset of a new inflammation in a patient already debilitated by disease. There is usually rapid prostration, restlessness, and delirium, with a tendency to stupor ; a pale, anxious face ; swollen belly ; persistent watery diarrhoea ; a frequent, wiry pulse, and quick, costal breathing. Pain, tenderness, tension of the abdominal walls, dulness on percussion and fluctua- tion may be entirely absent. Without care, such attacks are readily overlooked. Should peritoneal inflammation become chronic the pain lessens and is more paroxysmal in character ; the fever is remittent, with evening exacerbations ; constipation alter- nates with diarrhoea ; there is great emaciation, and death occurs from exhaustion. However, on account of the usual tubercular origin, the symptoms of this form will be more appropriately studied under the head of " tubercular peri- tonitis." Local peritonitis is almost uniformly secondary ; that attending inflammation of the caecum and vermiform ap- pendix being the most common in children. Diagnosis. — An immovable dorsal decubitus ; a pale, haggard face ; a frequent wiry pulse ; distension, pain and tenderness of the belly, and inactivity of the abdominal muscles in respiration, suffice to render the diagnosis of acute general peritonitis easy. Intense pain, sudden col- lapse and rapid and extreme meteorism characterize the perforative variety. In colic there is constipation and vomiting, with severe pain ; but between the paroyxsms there is no abdominal tenderness, and the pulse is never so rapid, small, and wiry, nor is there the fear of movement so noticeable in peritonitis. 312 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. Rheumatism of the abdominal muscles is attended by tenderness on pressure ; distressed facial expression ; dorsal decubitus with knees drawn up, and constipation, and thus simulates peritonitis ; but the face is never haggard, there is no vomiting nor hiccough, nor distension of the belly, neither is tenderness extreme. The pulse is soft, compres- sible, and only moderately frequent ; the temperature nearly normal, and the urine scanty, high-colored, acid and scalding. It is important to remember that constipation is the rule in peritonitis when the inflammation involves and paralyzes the muscular coat of the bowel ; diarrhoea, when it spreads through the muscular coat to the mucous membrane. The great difficulty in diagnosis is experienced with latent peritonitis, whether septic or due to other causes. Suspicion of its existence may be entertained when, in the course of any predisposing disease, the patient suddenly grows pale and haggard, and has a full belly, with a tendency on the part of the abdominal muscles to become rigid on palpation. Restlessness, delirium and stupor, a change in the type of respiration and in the character of the pulse, all strengthen the suspicion. Under these cir- cumstances it is well to practice Duparcque's method for detecting the presence of fluid, and this, if successful, leaves no further doubt. In the words of Eustace Smith : " In cases of chronic empyema we should always be on the watch for the occur- rence of peritonitis. If the child, after a period of im- provement, cease all at once to gain ground, and begins to look pale and distressed, with an elevated temperature, a more or less distended belly, and a rapid, wiry pulse, we are justified in suspecting peritonitis, although there be no tension, tenderness or other sign connected with the abdo- men to give support to this opinion." AFFECTIONS OF THE PERITONEUM. 313 Prognosis. — This must always be most grave. Perfora- tive peritonitis is invariably fatal. The primary variety, when due to cold, exceptionally ends in recovery, and so, too, does the partial form. Treatment. — Absolute rest in bed and quiet surround- ings are essential. Hot applications, in the form of light flax-seed poultices and of turpentine stupes, should be made to the surface of the belly; or, if these fail to give relief, cloths wrung out of ice-water may be applied ; they must be frequently changed, to secure the constant action of cold. Leeching is sometimes of great service in subduing pain, but it is only to be employed with robust subjects and in an early stage of the attack. Of drugs, opium alone can be relied upon. It may be exhibited by the mouth, the rectum, or subcutaneously, and can safely be pushed to the point of producing drowsi- ness, with decided contraction of the pupils, provided ease from suffering be not attained before. For a child of six years, three drops of laudanum every two hours, by the mouth or rectum ; and, by hypodermic injection, one-eigh- teenth of a grain of sulphate of morphia, repeated as re- quired, are the average commencing doses. Under no circumstances is a purge to be given. Should constipation be obstinate, and the indications urgent to un- load the bowels, a simple enema may be employed. It is a good rule, however, to interfere as little as possible in this way. The patient's strength must be sustained by concentrated liquid food in small quantities and at short intervals. Three fluidounces of milk and two fluidounces of beef-tea, alter- nating, every two hours, with the occasional substitution of the yolk of a soft-boiled egg for one or the other, would be a proper diet for a child of six years ; stimulants are also 314 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. necessary, and so soon as there is evidence of failing strength a teaspoonful of good whiskey must be added to each portion of milk. Bits of ice may be allowed from time to time to allay thirst and quiet the stomach. Should the inflammation subside, the opium is to be gradually withdrawn and its place supplied by sorbefa- cients and tonics; at first mercury in alterative doses, or iodide of potassium, with quinine ; and, later, syrup of the iodide of iron. At the same time, the hot or cold appli- cation being removed, a weak mercurial ointment should be rubbed into the skin of the belly once or twice daily ; for example : — R . Ung. Hydrargyri, Ung. Belladonnae, aa t ^ij. Adipis, 2iv. M. S. — Use locally as directed. A most important point is to make no change in the diet, except, perhaps, to increase gradually the quantity of liquid food, until convalescence be fully established. 2. TUBERCULAR PERITONITIS. As a rule, peritonitis due to the presence of tubercle in the abdominal cavity runs a chronic course, and is asso- ciated with tuberculosis of some other organ of the body — of the brain or lungs, for instance; less frequently it occurs as an isolated affection. Acute tubercular peritonitis is not unknown ; it is detected with difficulty during life, and is invariably an element of general tuberculosis. The disease is quite common after the age of seven years, but is rare in earlier childhood and almost never met with in infancy. AFFECTIONS OF THE PERITONEUM. 315 Morbid Anatomy. — At the autopsy of a child dead from tubercular peritonitis, the intestines will be found covered by a layer of yellow, greenish or gray lymph, varying in thickness, and either loose and soft in texture or tough. Lymph having the same characters also covers the parietal peritoneum, and extends between the intestinal coils, binding them, more or less firmly, together. The exudate contains caseous masses of variable size; its meshes are filled with greenish-yellow, sometimes bloody, sero- purulent effusion, and a quantity of the same material is usually found in the dependent portions of the abdominal cavity. Removal of the layer of lymph discloses gray and yellow tubercles, studding the surface of the peritoneum, together with masses and broad plates of caseous consist- ence and tuberculous nature. The thickness and extent of the exudation, the number of granulations, and the size of the caseous masses increase with the chronicity of the attack. In acute cases the cheesy collections are absent ; the exudate is comparatively thin, soft and translucent, and the granulations, which vary in size from that of a pin's head to that of a pea, are scattered at intervals through its substance. The omentum is shriveled, hard and often firmly bound to the abdominal wall; the mesentery is firm and con- tracted ; the mesenteric glands are enlarged and show evidences of cheesy or tubercular alteration; tubercular ulceration of the bowels is common, and the liver may be increased in size from amyloid or fatty change, and in some instances is cirrhotic. Inspection of other organs of the body usually leads to the discovery of tubercle, though this is not uniformly the case. Tubercular peritonitis is not always general in distribu- tion ; when localized the inflammation and inflammatory 3 16 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. products are usually to be observed in the neighborhood of the diaphragm. Etiology. — The factors leading to peritoneal tuberculosis are identical with those producing other tubercular affec- tions. The age at which the disease is most prone to occur has already been mentioned. Male children seem to suffer more frequently than those of the opposite sex. Symptoms. — The onset is slow and insidious, and the physician is apt to have his attention diverted from the abdomen by more striking manifestations of tuberculosis of the lungs or other organs. Unless such features be pres- ent and precedent, there is but little evidence of failing health in the beginning, and the first symptom to attract notice is an abnormal prominence of the belly. The patient gradually grows dull and listless, looks ill, and, on account of abdominal tenderness and the pain produced by jarring, becomes slow and guarded in his movements. Often after the disease is fully developed the child " keeps about," but the face is drawn and wears an expres- sion of anxiety and suffering ; the frame slowly wastes and the skin becomes dry and harsh and loses its healthy hue. Complaints are made of tenderness and griping pains in the abdomen, and the little sufferer takes very char- acteristic precautions to lessen his ills by steadying his belly with his hands in walking, and by moving down- stairs backward so as to pass from step to step on his toes, to avoid jolting. The symptoms denoting disturbance in the functions of the gastro-intestinal tract are inconstant at this stage of the disease; the tongue either shows little alteration or is lightly frosted or more pointed and red than natural ; nausea and vomiting may be entirely absent, and are never so persistent and severe as in simple perito- nitis ; the appetite often remains unimpaired, and the bowels AFFECTIONS OF THE PERITONEUM. 317 are alternately relaxed and confined. On the other hand the signs to be detected by abdominal exploration are very constant and characteristic. The belly is oval in shape and somewhat irregularly distended, the greatest enlargement occupying the epigastric and umbilical regions ; the natural folds and furrows are obliterated ; the superficial veins are prominent ; and the integument has a smooth, shining ap- pearance, as if smeared with oil. When the hand is applied to the surface, the recti muscles become tense, in an involuntary effort to protect the tender parts beneath ; some portions of the abdomen feel soft and flaccid ; in others, firm masses are perceptible to the touch; tenderness on pressure is universal, though most marked over the firm masses. Palpation also reveals fluctuation ; this is usually indistinct, though occasionally, when enlarged glands or cheesy masses exert pressure on the portal vein, there is a large collection of fluid in the peritoneal cavity, and the fluctuation wave is readily elicited and very distinct. The edge of the right lobe of the liver can often be felt extend- ing half an inch or more beyond the right costal border. On percussion, tympany will be elicited over the flaccid portions of the abdomen; dulness over the firm masses and flatness over the flanks — in the recumbent position — while, if the patient be rolled to one side, the note on the flank turned uppermost becomes tympanitic. The respiratory movements are somewhat increased in frequency and thoracic in type ; the pulse is quickened and feeble in proportion to the general weakness ; the axillary temperature ranges from 98 F. in the morning to 10 1° in the evening ; and there is dysuria with high-colored, but other- wise unaltered, urine. Sometimes, with a large collection of fluid in the peritoneum, there is oedema of the feet and legs ; then, too, the urine may be slightly albuminous. 3 18 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. In time the patient is forced to go to bed, where he lies on his back, or partially turned on one side, with his legs drawn up ; this position is rigidly maintained, for every movement is painful. Now, the wasting is rapid ; the face wears a haggard expression ; the cheeks and temples are hollow, and the skin becomes inelastic and dotted with purpuric spots. The tongue is dry, heavily coated, or red and smooth; the appetite fails and there is urgent thirst. The bowels are in one of two conditions : relaxed, with watery, offensive stools, containing flaky matter and small black clots of blood when there is tubercular ulceration ; obsti- nately confined, when the intestines are pressed upon, or obstructed by adhesions. In the latter case the belly ber comes greatly distended, and there are frequent attacks of severe colicky pain. Under other circumstances, however, the size of the belly may diminish, and then hard, tender lumps are felt in contact with the abdominal wall. The pulse is more frequent and feeble; the evening temperature ranges as high as 103 and 104 , and night sweats are common. Death occurs after a lapse of time varying from several months to a year or more. The course of the disease is not uniformly progressive, being interrupted by remissions and exacerbations. During the former the tenderness and distension of the abdomen diminish, the appetite returns, nutrition improves, and false hopes arise of rapid recovery. Sometimes before death an abscess forms, and pus is dis- charged through the abdominal wall in the neighborhood of the umbilicus ; in other cases the intestines may be per- forated from without, but this complication scarcely has- tens the fatal termination, for extravasation is limited by adhesions between the knuckles of the intestines. Such AFFECTIONS OF THE PERITONEUM. 319 complications as tuberculosis of the lungs and cerebral meninges, however, certainly hasten death. Acute tubercular peritonitis always occurs as an element of disseminated tuberculosis, and presents the general fea- tures of that condition ; usually there are no local manifes- tations other than abdominal fulness and slight pain — symptoms sufficiently common in children to be altogether indefinite. The course of these acute attacks is measured in little more than a week. Diagnosis. — Ordinarily the formation of a correct opinion is not difficult. The distinctive features are the irregular distension of the abdomen ; the smooth, shiny appearance of the investing skin ; tenderness ; unequal resistance to the touch in different positions, and indistinct fluctuation, combined with alterations in the temperature ; impairment of nutrition ; an insidious onset ; a family record of tuberculosis or scrofula ; the presence of the tubercular diathesis, and the existence of symptoms of tubercular deposit in some other organ of the body. In doubtful cases, where there is little distension or tenderness, and fluctuation is absent, it is well to try the effect of a sudden jar; this may be done by directing the child to jump from a low chair to the floor. Free fluctuation is to be regarded as a point in the negative. Many children have prominent bellies and suffer severely from abdominal pain, both due to the accumulation of flatus in the intestines, the consequence of a chronic ca- tarrh of the mucous lining. These patients, though pale and flabby, are but little wasted, and express in their faces no trace of severe illness ; they are lively in action ; their temperature is normal ; there is no tenderness or involun- tary contraction of the recti muscles on palpation ; the abdominal distension disappears spontaneously at times, 320 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. and subsides entirely when a non-farinaceous diet is or- dered. There can be no greater mistake than that of attributing every instance of abdominal distension to tuber- culosis. As already stated, the diagnosis of the rare acute form is very difficult, and is often only made at the post-mortem table. Typhoid fever is the disease most likely to be confounded with it, but the absence of rash and splenic enlargement, and the difference in the degree and course of the fever, should prevent error. Prognosis. — This must always be unfavorable. Recov- ery, though possible, is extremely rare. Treatment. — While little is to be expected from thera- peutic measures, the physician's ambition will be to obtain a favorable result if he can. To accomplish this end it is necessary, first, to keep the child at perfect rest in bed ; and second, to select a diet that will meet the capacity for digestion, excluding as nearly as may be the farinaceous foods so prone to cause acidity and flatulence, with their attendant suffering. The following is a sample diet list for a patient of seven years : — For breakfast, at 7.30 a.m. — The yolk of a soft-boiled egg, a slice of well-toasted bread lightly buttered, and a tumblerful (f^viij) of warm milk. For luncheon, at 12 m. — The soft parts of a dozen oysters or a bit offish, or a bowl (f3vj) of good beef-tea, with a biscuit. For dinner, at 3 p. m. — Two to four tablespoonfuls of minced mutton or chicken, one or two thin slices of stale buttered bread, eight tablespoonfuls of rice and milk or junket. For supper, at 7 p. M. — Two slices of milk-toast and a tumblerful of warm milk. AFFECTIONS OF THE PERITONEUM. 321 Such a list can only be used in the earlier stages of the disease ; later, when the appetite fails, it is necessary to resort to liquid food, milk and meat broths, administered in small quantities at short intervals. Stimulants — and whiskey is the best — are required from the beginning, and must be given in increasing quantities as the strength fails. Of drugs, opium, quinine, and syrup of the iodide of iron with cod-liver oil, when the stomach will bear them, are the most useful. Opium must be given sufficiently freely to relieve pain, and quinine in doses large enough to main- tain the flagging forces. Constipation is to be remedied only by simple enemata, while excessive diarrhcea may be checked by full doses of bismuth combined with ipecacu- anha and opium, as : — 1$ . Pulv. Ipecacuanhse Comp., gr. xxiv. Bismuth. Sub-carb., gj. Pulv. Aromat. , gr. xij. M. et ft. chart. No. xij. S. — One powder every two or three hours for a child of seven years. A good formula for the same purpose is :— R . Ext. Haematoxyli, gr. xxx. Tr. Opii Deod., TT\xxiv. Vin. Ipecacuanha, rTLxxxvj. Mist. Cretae, q. s. ad f^iij. M. S. — Two teaspoonfuls every three hours. Externally, light flax-seed poultices are useful in relieving pain. Sometimes even the lightest poultice is uncomfort- able, then the abdomen may be anointed once daily with — R. Ext. Belladonnae, ^ij. Glycerinse, f^vj- M. and covered with a thick layer of cotton batting. 21 322 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. Should the quantity of fluid in the peritoneum be large, diuretics and diaphoretics are indicated ; if excessive, para- centesis is required. 3. ASCITES. The collection of a quantity of transparent serum in the sack of the peritoneum is not of very common occurrence during childhood. The condition is, probably, always secondary, and must be regarded rather as a symptom than a disease proper ; it is of sufficient import to warrant a brief, separate consideration. Etiology. — Ascites is sometimes produced by simple or tubercular inflammation of the peritoneum ; more fre- quently it depends upon obstruction to the return of venous blood, due to diseases of the liver or heart ; to enlargement of the mesenteric glands, and, occasionally, to disease of the lungs ; again, it may be the result of a general hydraemic state of the blood, attending affections of the kidneys and anaemia. It is occasionally impossible to decide upon the preexisting lesion. Symptoms. — In a well-developed case the abdomen is distended and globular, the exact shape depending upon the position of the patient, being broader in the recumbent than in the erect posture, as, then, the fluid tends to spread and collect in the flanks. The integument is smooth and shining ; the superficial veins are very distinct, and the normal depression at the umbilicus is either effaced or there is a projection at this point. There is a sense of fulness, with moderate resistance, but no tenderness on palpation ; and if a hand be placed on either side of the belly, and a sharp tap given with one of the fingers, a distinct impulse AFFECTIONS OF THE PERITONEUM. 323 — fluctuation wave — is felt by the other hand ; this is not interrupted by pressure, made by an assistant, on the me- dian line. While the child lies upon his back, percussion is tympanitic over the upper anterior parts of the belly, where the intestines float free, and dull elsewhere ; a change in position alters the relation of the areas of tympany and dulness, and the extent of the latter depends entirely upon the amount of fluid present. Pain is not a prominent symptom ; if present, it is par- oxysmal, and has the griping character of the colic of intes- tinal indigestion. Such attacks are often attended or followed by moderate diarrhoea ; in the intervals the bowels may be confined. Should the effusion be large the mere weight of the fluid causes discomfort; then, too, respiration is embarrassed, even to the extent of orthopncea ; micturition is painful ; the urine is scanty, high-colored and albumi- nous, and there may be oedema of the genitalia and legs, resulting solely from pressure. Cases having an obscure etiology furnish few additional features ; there are no constant or characteristic alterations of the tongue, appetite, appearance of the skin or tempera- ture ; for these, with other rational symptoms, depend upon the determining disease. When due to inflammation of the peritoneum, the amount of effusion is small ; the abdomen is tense and tender ; the temperature is usually elevated, and the gen- eral symptoms of acute or chronic peritonitis are more or less marked. In hepatic diseases, especially cirrhosis, the effusion is great ; the superficial abdominal veins are very prominent ; the hemorrhoidal veins are distended ; the spleen is often enlarged ; the digestive functions are impaired, and the gen- eral integument has a sallow hue or is decidedly jaundiced. 324 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. Cardiac disease causes anasarca and hydrothorax as well as ascites, and these conditions are apt to be associated ; the face is livid ; the lips and finger tips blue ; the jugular veins are distended and pulsating ; there is dyspnoea, and a scanty, albuminous urine, with the physical signs of heart lesion. Diagnosis. — There is little difficulty in detecting ascites, unless the effusion be so small that it sinks away into the pelvis or between the folds of the intestine beyond the reach of the examiner's hand. Under these circumstances it is well to try Duparcque's method (see page 308) of in- creasing the distinctness of fluctuation, or to put in practice another plan for the same purpose, namely, placing the patient on the hands and knees so that the fluid may gravi- tate to the most dependent portion of the abdomen — now the neighborhood of the umbilicus — and come within the range of palpation. A large belly, produced by flatulent distension of the intestines, may yield indistinct fluctuation, the palpation stroke being transmitted through the bowels; but the imperfect wave is readily interrupted by pressure in the median line, and the results of percussion are quite different from those obtained in ascites. The collection of a large quantity of fluid in the pelvis of one or other kidney — hydronephrosis — is attended by abdominal distension, fluctuation, and percussion dulness. The enlargement, however, is more noticeable on the side of the affected kidney ; here, also, there is more resistance and greater dulness, the opposite flank being often tympan- itic; changes of position have little effect in altering the percussion sounds, the umbilicus rarely protrudes, a kidney- shaped outline can often be detected, and tapping liberates a liquid charged with urea. AFFECTIONS OF THE PERITONEUM. 325 The Prognosis depends chiefly upon the nature of the originating disease. When this cannot be discovered, the forecast must be based upon the general strength and nu- trition, the condition of the skin, the temperature, and the character of the urine. If the strength be moderately pre- served, the appetite and digestion fairly good, the skin nat- ural in texture and color, the temperature normal, and the urine free and non-albuminous, the prognosis for an ultimate recovery is good, irrespective of the amount of effusion. Treatment. — This must, in the main, be regulated by a consideration of the primary disease. Cases of obscure origin, as well as those depending upon anaemia or disease of the liver, are much benefited by full doses of iron. The tincture of the chloride of iron or the dried sulphate are, perhaps, the best preparations to use, and their effect is increased by the addition of quinine. The following is a serviceable formula : — R. Ferri Sulph. Exsiccat., . . . gr.xxiv (to be increased to 5 j). Quiniae Sulph., gr. xij. Acid. Sulphurici dil., . . . rr\xij. Syrupi, fgj. Aquae Menth. Pip., q. s. ad Hj iij. M. S — Two teaspoonfuls three times daily, taken diluted and after eating, for a child of six years. Diuretics can be employed at the same time, if there be no kidney complication, for example : — R. Potassii Acetatis, gij. Spt. Juniperis Comp., f^ ss - Spt. yEtheris Nitrosi, f^vj. Syrupi, f|ij. Aquas, q. s. ad f 5vj. M. S. — Two teaspoonfuls every three hours. A combination of acetate of potassium, squill and digitalis is often useful. 326 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. Should this class of remedies fail, much may be accom- plished by a properly regulated course of purgatives. For this purpose, thirty grains of compound licorice powder, or ten grains of compound jalap powder, may be given from two to three times daily. Sometimes it is advisable to begin this treatment by two grains of calomel, administered at bedtime, and followed next morning by a teaspoonful of magnesia. It is always important to keep the skin active by a daily warm bath, and to maintain an equal surface temperature by woolen underclothing. The diet should contain as little fluid as possible ; thus the child may eat : — For Breakfast. — A saucer of oat-meal porridge or cracked wheat with cream ; a soft-boiled egg ; two slices of stale bread or toast with butter ; a teacupful (four fluidounces) of milk. For Dinner. — A bit of roast chicken, or tenderloin of beef-steak, or roast beef or mutton ; mashed potatoes with gravy, or spinach or cauliflower; two or three slices of stale bread; rice pudding or junket and a glass of filtered water. For Supper. — A poached egg on toast, or a bowl of cream toast and a cup of milk. Between meals, some water must be taken to relieve thirst, but the less the better. When the fluid does not diminish after a thorough trial of ordinary remedies, the peritoneal cavity must be tapped. It is best to make the puncture with a very fine canula ; the instrument having been inserted is left in position ; a rubber tube is attached, and the fluid allowed to drain away slowly for some eight or ten hours, constant and equal pressure being maintained in the meanwhile by a broad bandage. After the canula is removed, the abdomen must AFFECTIONS OF THE PERITONEUM. 327 either be strapped or carefully bandaged. The effusion is never entirely removed in this way, but enough is taken to relieve pressure and allow absorption to go on. This method of operation causes so little pain, that, if necessary, but slight objection is offered to its repetition; in very timid subjects, though, it is well to lessen the sensibility of the skin by the momentary application of ice and salt to the point selected for puncture. Paracentesis is often a remedial agent of much value ; though in some cases it is merely palliative. PART III.— THE GENERAL MANAGE MENT OF CHILDREN. It is the duty of the child's physician not only to remove disease, but also to manage convalescence and every-day life in such a way that the little subjects confided to his care may be led to complete recovery, and kept in as per- fect health as possible. To accomplish these objects, the ability to direct intelligently the daily regimen is much more important than a mere knowledge of drugs and of the prin- ciples of therapeutics. The daily regimen embraces several factors ; these are feeding, bathing, clothing, sleep and exercise, and under such headings the subject will be briefly outlined, for little more is possible, in the present chapter. i. Feeding. Age bears so close a relation to the choice of food and the method of feeding, that it will greatly simplify the study of these questions to consider them from the standpoint of the two stages of a child's life, namely, infancy, or the period extending from birth to the age of two and a half years ; and childhood, the time elapsing between completion of the first dentition and puberty. An Infant may be fed in either one of three ways — a } from the mother's breast; b y from the breast of a wet-nurse; and c, from a bottle, the latter being the method known as artificial or hand-feeding. a. The mother's breasts are unquestionably the natural 329 330 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. source of food-supply for her infant, and the mother's milk the natural and, therefore, the best food. Consequently, every woman who is free from certain contraindicating dis- eases, to be mentioned later, should nourish her child solely in this way for the first eight months of its life and, partially so, up to the end of the first year ; or, failing in either limit, for as long a time as possible. The infant should be put to the breast as soon as the mother has recovered somewhat from the fatigue of labor — some four or eight hours after birth. Of course, no milk can be drawn at this early date, but the babe gets a small quantity of thin, watery colostrum, which affords suffi- cient nourishment, and, at the same time, from its laxa- tive properties, cleans the bowels of meconium. This pro- cedure, too, is of great advantage to the mother, for it in- sures proper uterine contraction, draws out the nipples, and encourages the formation of milk. As the secretion of milk is never fully established until the third day after labor, it stands to reason that no food other than the colostrum is required before that time. Hence, the practice of filling the infant's stomach with gruel, sugar and water, butter and sugar, and other sweetened mixtures, is more than useless, for it diminishes the activity of sucking and the consequent stimulation of milk-produc- tion. Put the child to the breast every two hours while the mother is awake, and there need be no fear of starva- tion. After the third day, should the breasts not yield a supply of milk, a little sound cows' milk, diluted with double its quantity of water and sweetened with sugar of milk, may be given every fourth hour, the babe being put to the breast in the meanwhile. So soon as the flow begins, however, artificial feeding is to be discontinued. THE GENERAL MANAGEMENT OF CHILDREN. 33 1 Usually on the fourth day milk is secreted and regular lactation commences. Many untrained mothers make a failure of nursing because they know nothing of the manner of giving suck ; of the length of time the child should be at the breast; of the proper time for, and interval between, feeding, and of the importance of regularity. Upon these points the physician must be able, if required, to give minute instructions. When giving the breast, the infant must be held partly on its side, on the right or left arm, according to the gland about to be drawn, while the mother must bend her body forward so that the nipple may fall easily into the child's mouth, and steady the breast with the index and middle finger of the disengaged hand, placed above and be- low the nipple. In case the milk run too freely — a con- dition very apt to excite vomiting — the flow is easily regulated by gentle pressure with the supporting fingers. Each breast should be drawn alternately, the contents of one being sufficient for a meal, and a healthy child may be allowed to nurse until satisfied, when he will stop of his own accord, drop the nipple, and fall asleep with milk still running over his lips. During the first six weeks, the breast is required every second hour, from 5 a.m. to i i p.m. Then the infant should be put in a crib by the mother's bed, or, better still, in the nurse's room, and there remain quietly until the morning feeding. This secures the mother six hours' uninterrupted repose, a matter of great importance to her general health and consequent capacity for prolonged lactation. As to the infant, he may rebel at first, and wake and cry, so that it is necessary to quiet him with a little milk and water administered from a bottle ; but often after a few days, and certainly at the end of a week or two, the good custom 332 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. of sleeping at night is formed, and there is no further trouble. Regularity in meal hours is of even more importance in early than in adult life, on account of the natural feebleness of digestion. To secure this, it is only necessary to have a little perseverance ; for infants are such creatures of habit, that a short training brings them into the way of expecting food only at certain times, and, when healthy, they wake to suck with almost the precision of the clock. While insisting upon this rule, one must recognize the fact that, although, in the vast majority of instances, a two hours' interval is most suitable up to the middle of the second month, there is no absolute law as to the daily num- ber of nursings. Some infants seem to need food less frequently, and it is best to respect their peculiarity, and not force the breast upon them so long as they sleep well, do not fret when awake, and thrive generally. Others, again, may require it oftener; every hour and a half, per- haps, and even once or twice at night. In these excep- tional cases an appropriate schedule can only be made by close observation of individual characteristics. A common and most ruinous mistake is to resort to constant feeding as a means of pacifying crying. Babies certainly do cry from hunger, but just as frequently the crying results from colic or from the discomfort and pain of indigestion. Every mother should be able to recognize the difference. The cry of hunger usually begins after a sound sleep, is not peevish, and stops at the sight of the breast, when the infant rouses himself, presents an expres- sion of pleasure, clinches his hands and flexes the limbs. The cry of colic is violent and paroxysmal ; the face is livid, and wears an expression of suffering ; the abdomen is distended and hard ; the hands and feet are cold ; the legs THE GENERAL MANAGEMENT OF CHILDREN. 333 are drawn up or kicked violently about ; and an explosion of wind from the mouth or anus ends the attack. A peevish cry, hot skin and sour breath, attend indigestion. It stands without the saying that the cry of hunger must be relieved by giving food, but this is the very worst thing to do under other circumstances, for it both breaks up good habits and produces serious mischief. The pain of colic and the discomfort of indigestion are chiefly due to the accumulation of flatus resulting from the fermentation of food. Mothers soon learn, and unfortunately infants too, that the breast-milk temporarily relieves suffering. This it does, in the same way as any other warm liquid; but, unlike a simple fluid, milk only adds more material to the already fermenting contents of the gastro-intestinal canal, and every nursing is soon followed by more pain, until between crying and sucking, and sucking and crying, the infant's life is passed in misery if not cut short altogether. Instead of continuous feeding, the plan for relief is to decrease the quantity of food by increasing the intervals between nurs- ing, and by abridging the time of lying at the breast, while therapeutic measures are employed to strike at the root of the evil. After the sixth week, the interval between nursings may be slowly increased until, by the fourth month, it reaches three hours. During this period, also, the time of lying at the breast may be gradually lengthened, for the quantity of milk secreted and the child's appetite and capacity .for food are all augmented as the days pass by. At the end of the sixth month, feeding every fourth hour suits some children well, but, as a rule, the three-hour interval must be adhered to from the fourth month to the end of lactation. Many authorities recommend additional artificial feeding, alternating with nursing, after the sixth or eighth month. 334 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. Such a plan is perfectly proper if the babe ceases to gain strength and flesh while on the breast. If otherwise, the maxim of not interfering with any course that is doing well is as applicable here as elsewhere, and the breast may be relied upon entirely until the time comes for weaning. Should additional nutriment be required, the food must be selected with due reference to age and prepared in the same manner as in regular hand-feeding. The date of weaning cannot be exactly fixed for all cases, since it must depend upon two conditions — the health of the mother and the development of the infant. When the former continues to be robust, and the child steadily grows and gains flesh, lactation can be prolonged until the tenth or twelfth month. If persevered in longer the mother's strength begins to fail, her milk is lessened in quantity or becomes poor in quality, the child's nutrition suffers and he grows pale, thin and flabby and may develop rickets. Change in the manner of feeding may be accomplished gradually or suddenly. In gradual weaning, about four weeks are required to prepare for the absolute withdrawal of the breast. For instance, if suck be given every three hours, from 5 a.m. to i i p.m., or seven times a day, there should be during the first week of preparation one artificial feeding and six nursings daily ; during the second, two and five ; during the third, four and three ; and during the fourth, six and one. Then the breast must be entirely with- held. Carefully prepared milk-food, administered from a bottle, is the best substitute. At the age of ten months a mixture that ordinarily agrees well is : — Cream, f^ ss - Milk, fjijss. Sugar of milk, gss. Water, f£j. THE GENERAL MANAGEMENT OF CHILDREN. 335 This is to be poured into a perfectly clean bottle, warmed in a water-bath, and taken through a clean, plain rubber tip. Should the quantity (four fluidounces) be insufficient to satisfy the child's appetite all the ingredients except the cream may be increased until the mixture measures six, eight or even twelve fluidounces, according to the demand. When such accidents as fever, disordered digestion with vomiting and diarrhoea, or the actual cutting of one or more teeth, occur during the period of preparation, the number of artificial feedings must be reduced, or the breast resumed until the disturbance be passed ; then the course may be begun again and carried to its completion. Usually there is little trouble in weaning infants in this way. Sometimes they become fretful under the change and may refuse food entirely for a day or more, but a little determination on the part of the mother and the cravings of hunger soon overcome this difficulty, while the breast is being presented at times. Sudden weaning is not advisable unless there be an absolute refusal to take artificial food, from either a bottle or a spoon. This is most apt to occur when food has been given too frequently, and when the breast has been used as a means to quiet crying. The plan is also to be recommended when the mother's health becomes so affected as to render any further sucking a positive peril to the child's life; rapidly developing pulmonary tuberculosis, and attacks of erysipelas or of variola, are instances in point. Ill-health of either the mother or the infant often re- quires premature withdrawal of the breast, thus necessitat- ing wet-nursing or hand-feeding. So far as the mother is concerned, lactation must be stopped if it reduce her strength and make her thin and pale. Frequently, women who are unable to nurse their 336 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. children entirely, without sacrificing their health, can safely do so several times in the twenty-four hours ; this partial sucking must be encouraged, for with its assistance hand- feeding becomes a safe and easy task. A change must also be made if pulmonary tuberculosis is developed, or, being already present, rapidly advances under the drain of milk-secretion ; and if any acute disease, as typhoid or typhus fever, occasion dangerous temporary prostration. On the part of the infant, there are several indications for anticipating the time of withdrawing the mother's breast. Thus, it must be done if the occurrence of pregnancy or the recurrence of menstruation render the milk unwhole- some ; if the mother contract a dangerous contagious disease, as variola, scarlet fever, or erysipelas ; or if the mammary glands become inflamed ; again, if the breast does not afford sufficient nourishment and artificial food be refused ; and finally, if dentition be markedly delayed and the premonitory symptoms of rickets appear. As to the third indication, it must be remembered that the breast-milk may be of good quality but so diminished in quantity that it is insufficient ; or, while abundant in quantity so poor in quality that it does not meet the de- mands of nutrition. Even without a minute examination of the milk, it is possible to form a pretty good idea of which condition is present from the behavior of the infant in the act of sucking. If the milk be good in quality but deficient in quantity, the babe, when put to- the breast, seizes the nipple as if famished, draws upon it vigorously for a moment or two, and then drops it with a scream of rage. On the contrary, should there be an abundant supply of poor milk, the nipple is grasped languidly, the child lies a long time at the breast and falls asleep there. THE GENERAL MANAGEMENT OF CHILDREN. 337 Consideration of the final indication opens the question of the propriety of regulating weaning by the progress of dentition. This is certainly a good guide, but not in the way implied in the old precept that the child must not be taken from the breast until evolution of the canine teeth. Insufficient food is one of the chief causes of rickets, and rickets, more than any other disease, delays dentition; conse- quently, should the teeth not pierce the gum in time, the inference is for other food rather than a continuance of the faulty maternal supply. Upon deciding to anticipate the time of weaning, the next point to consider is whether the infant shall be brought up by hand or by a wet-nurse. b. The advantage of feeding from the breast of a wet-nurse is that the mother's milk is substituted by the milk of another woman ; in other words, that natural feeding is continued, a matter of moment in all cases, and of inesti- mable importance with delicate children. The disadvan- tages consist in the great difficulty of finding, in a woman belonging to the class from which wet-nurses come, all the moral and physical characters essential to a good substitute, and the fact that a stranger is introduced into the household often to deceive and annoy the family, and on the slightest provocation to leave her charge to fate or to the tender mercies of another of her kind. For these reasons it is preferable, in the majority of instances, to trust to careful bottle-feeding. Nevertheless, as some child- ren must have human milk if their lives are to be saved, the rules for selecting a wet-nurse must be understood. The woman chosen must be strong and robust, but rather spare than fat. Her bill of health must be perfectly free from hereditary tendency to mental or physical disease and from the taint of syphilis, tubercle or scrofula. She 22 33^ DISEASES OF DIGESTIVE ORGANS IN CHILDREN. must be cheerful, good-natured, active, careful and temper- ate in habits. Her age should be between twenty and thirty years ; she should be a multipara, that she may under- stand the care of an infant and the manner of giving suck ; her child ought to be of nearly the same age as the infant about to be adopted, and she must be able to afford an abundant supply of good milk. The last quality can be estimated by inspecting the breasts, by examining some of the milk drawn by a pump, and by ascertaining the condition of the woman's own child. The breasts of a good nurse are not necessarily large, but are firm to the touch and pyriform in shape, with well-developed, prominent nipples, and with the skin distinctly marbled by large, blue veins. The milk, which ought to flow readily on pressure or on suction, should be opaque and dull white in color, have a specific gravity of 1032, an alkaline reaction, and show, when placed under the microscope, a number of medium-sized fat globules. Its quantity may be ascertained by weighing the child before and after sucking, the normal gain being from three to six ounces. There is, however, no better nor more readily applied test of the quality of a nurse than the size, weight and general development of her child, and if it be weak and ill-nourished, no amount of apparent fitness in other respects can warrant her engagement. Even when a woman is found fulfilling in her single person all of the above conditions — a rare event, indeed — it does not necessarily follow that her milk will suit the babe to be suckled. Then changes and new trials are in order until the desired end be attained. The diet of a wet-nurse must be liberal, including a moderate allowance of vegetables and fruit ; wine or beer may be taken with the mid-day dinner, when there is any failure in the supply of milk. THE GENERAL MANAGEMENT OF CHILDREN. 339 Weaning from the wet-nurse is to be commenced at the same time and conducted in the same manner as from the breast of the mother. c. In my experience, there are few American women, especially in the well-to-do classes, who do not look upon the duty of nursing their babies as a pleasant one; but there are many who are completely unable to do so, and a vast number in whom the secretion of milk fails after a few weeks or months of lactation. They must, through no fault of their own, resort to a wet-nurse or to artificial feeding. Usually they select the last method, with results that vary in direct proportion to the care and intelligence displayed in carrying it out. There can be no doubt, though the statement is a bold one and seemingly contrary to nature, that, taking the aver- age, infants properly brought up by hand are better devel- oped and enjoy more perfect health than those completely breast-fed. Of course, there is no artificial food equal to the natural — the sound breast-milk of a robust woman — and a child fed upon this must thrive, if other circumstances be favorable. Unfortunately, the woman who has sufficient health and strength to furnish an abundant supply of good milk during the ten or twelve months of normal lactation is unique in our day, and the great bulk of those who do nurse their children grow pale, thin and feeble, and give milk which, though sufficient in quantity to fill the suckling's stomach and satisfy the cravings of hunger, does not con- tain enough pabulum to meet the demands of nutrition, Such mothers complain that their children are puny, peevish and always ailing, and wonder why their neighbors' babies, fed upon the bottle, are so round, jolly and healthy. The explanation lies in the simple fact, that good cows' milk is a better food than bad breast-milk. 340 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. Infants can be reared perfectly well upon the bottle, but much more care and trouble are involved than in breast- feeding. The task is comparatively easy to accomplish when the powers of digestion are inherently active, and especially when artificial feeding is not required until after the child has been suckled for several weeks. In these cases the stomach and intestinal canal, inactive in foetal life, are trained to their new duties under normal conditions, and so prepared for the digestion of properly selected artificial aliment. On the contrary, if digestion be naturally feeble, or if the infant have to be bottle-fed from the first, great difficulty may be expected, and most skillful handling is demanded. To insure success in hand-feeding, it is necessary to re- member that an infant is not nourished by the food he simply swallows, but by that portion of it which he digests and assimilates. The best diet, therefore, is one so adapted to age and digestive power that everything eaten will be digested and absorbed. But since children differ as much in consti- tution as in feature, it is impossible exactly to formulate a food that will be applicable to every case, or one that needs no change from month to month of progressing growth. As age and strength increase, there is a corresponding development of the gastro-intestinal functions and a call for more and stronger food. On the other hand, should the system be accidentally reduced by disease, the digestion, sympathizing in the general debility, temporarily loses its normal activity and assumes that of an earlier age. Now, more nourishment is certainly needed to build up the failing strength, but it is to be supplied by giving such food as can be completely assimilated, and not by forcing down strong food merely because it is strong. For the latter, when not vomited, passes through the bowels undigested, and the THE GENERAL MANAGEMENT OF CHILDREN. 34 1 little creature starves to death in the midst of plenty, or dies from the ill-effects of the constant presence of fermenting food in the alimentary canal.* On these accounts, many changes in diet, as to quality and quantity, must be antici- pated and made. Other important matters to be studied in detail are — 1st, the selection of a proper substitute for the breast-milk ; 2d, the quantity to be given ; 3d, the method of preparation ; 4th, the mode of administration; and 5th, the means of preservation. 1st. Healthy breast-milk must be taken as the type of infants' food, and the nearer an artificial substitute can be made to approach it in chemical composition and physical properties, the more perfect is it. Normal breast-milk has a specific gravity of about 1032, is alkaline in reaction, as already stated, and is composed of:— Water, 889.08 parts. Sugar, 43.64 " Casein, 39-24 " Butter, 26.66 " Salts, 1.38 "f It contains, then, albumen, carbohydrates, salts and water, all the elements essential to repair tissue waste, to supply new material for growth, and to maintain body-heat, or, in other words, to constitute a perfect aliment ; and these, too, are so proportioned in the combination as to meet the de- mands most easily and completely. In seeking a substitute, one naturally turns to the domestic animals for the source of supply. Between the milk of the ass, cow, goat and ewe there is little choice, so far as com- position is concerned, though, perhaps, asses' milk resembles * See Simple Atrophy. f Analysis of MM. Vernois and Becquerel. 342 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. that of women a little more closely than the others ; never- theless, cows' milk is usually selected, because, being plen- tiful, it is easily obtained and cheap.* Cows' milk has a specific gravity of 1033.38, is slightly acid in reaction — unless perfectly fresh from a pasture-fed animal — when it may be neutral or alkaline, and contains: — Water, 864.06 parts. Sugar, 38.03 " Casein, 55.15 " Butter, 36.12 " Salts, 6.64 " f Comparing this analysis with that previously given, it is readily seen that the two fluids differ in specific gravity and reaction, and that cows' milk contains more casein and fat, but less sugar, than woman's milk. Another difference of much consequence is, that if rennet be added to cows' milk, the casein coagulates into large, * An interesting table, from Vernois and Becquerel, is given by J. Lewis Smith, showing the difference in the composition of human milk and that of the four common domestic animals : — Variety of Specific Gravity. 1000 parts contain The solids consist of Milk. Fluids. Solids. Sugar. Butter. Casein. Salts. Woman 1032.67 889.08 110.92 43- 6 4 26.66 39-24 1.38 Cow.' 1033-38 864.06 135-94 38.03 36.12 55-15 6.64 Ass IQ34-57 890.12 109.88 50.46 18-53 35-65 5-24 Goat I033-53 844.90 155-1° 36.91 56.87 55-14 6.18 Ewe 1040.98 832.32 167.68 39-43 54 31 69.78 7.16 f Analysis of Vernois and Becquerel. THE GENERAL MANAGEMENT OF CHILDREN. 343 firm masses, while with human milk a light, loose curd is formed. In the stomach the gastric juice has the same effect as the rennet ; producing, in the first instance, a coagu- lum most difficult to digest; in the other, one readily at- tacked and broken down by the gastro-intestinal solvents. These chemical and physical properties of cows' milk can be altered by various methods of preparation, and unless this be done, there are few instances in which it will not prove a poor substitute for the natural food. Condensed milk is frequently recommended by physicians, and largely used by the laity, on their own authority, in bottle-feeding. It keeps better than cows' milk, and is sup- posed to be more easily digested by young infants. The latter supposition is a mistaken one, and arises from the overlooked fact that condensed milk is always given dis- solved in a large proportion of water, while cows' milk is too frequently used insufficiently diluted, or otherwise im- properly prepared. The author is convinced of the accuracy of this statement from a number of years' close study of the subject, during which he has seen but two or three instances where properly prepared cows' milk was unsuitable, provided condensed milk could be digested, and he has had little diffi- culty in substituting the former for the latter when the cooperation of the mother and nurse was obtained. Condensed milk contains a large proportion of sugar, forms fat quickly, and thus makes large babies ; the sugar also, counteracts a tendency to constipation, often a trouble- some complication of hand-feeding. These advantages are unquestioned, and, together with the ease of prepa- ration, are what place it so high in the esteem of monthly nurses. It is equally true that, as a food, it does not contain enough nutrient material to supply the wants of a growing baby. According to Meigs' analysis, the mixture 344 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. of condensed milk ordinarily used — one teaspoonful to six tablespoonfuls of water — yields : — Water, 92.673 parts in 100. Fat, 1.095 " " Casein, 868 " Sugar, 5.206 " " Ash, 158 '* " It is apparent that the amount of casein and of fat is much less than in either human or cows' milk. The addition of a large proportion of condensed milk would remove this fault, but at the same time would increase the quantity of sugar to a point incompatible with perfect digestion. Infants fed upon it, though fat, are pale, lethargic and flabby ; although large, are far from strong ; have little power to resist disease ; cut their teeth late, and are very likely to drift into rickets before the end of the first year. Without going further into detail, it is never safe to bring up a child solely on condensed milk. For a tempo- rary change of diet, and as a food during traveling or under circumstances in which sound cows' milk cannot be ob- tained, it may be resorted to with advantage. The farinaceous substances so often selected, especially by the poor, to replace breast-milk, are not only bad foods, but have, both directly and indirectly, a deleterious effect upon the processes of nutrition. They are bad foods for two reasons. First, they differ materially from human milk in chemical composition. For example, in arrowroot, which is the favorite, the proportion of the nitrogenous to the calorifacient element is as one to twenty, while in human milk it is one to four. Secondly, because the calorifacient principle — starch — must be con- verted into sugar before it can be absorbed. This change is accomplished in the body by the saliva and pancreatic THE GENERAL MANAGEMENT OF CHILDREN. 345 juices, secretions that are not fully established until the fourth month. While the starch lies undigested in the gastro-intestinal canal it is subject to fermentation, resulting in the formation of irritant products that rapidly induce catarrh of the mucous membrane ; a condition directly interfering with the digestion and absorption of food. Again, perfect nutri- tion demands rapid waste and removal of effete tissues, as well as repair of the same. This is effected by oxidation. Now sugars are known to have a much greater affinity for oxygen than albuminates, and when the diet consists of farinaceous material, the little sugar formed and absorbed, appropriates oxygen that would otherwise go toward the removal of waste, and so retards the necessary changes. Farinaceous food, as such, is never admissible before the fourth month ; earlier, it is only to be employed as an addi- tion to milk preparations for its mechanical action. 2d. The quantity of food to be allowed each day varies with the appetite and age. Some infants habitually eat little, others much ; as both thrive, the question of the correct amount in a given case must be answered by obser- vation. So long as the child develops with normal rapidity and keeps well, he may be allowed to eat as much or as little as he wants, for if food of proper strength be given at regular intervals, the instinctive cravings of hunger, since they represent the wants of the system, rarely lead to ex- cess in either direction. Nevertheless, it is well to have some guide. During the first four weeks, infants generally require from twelve and a half to sixteen fluidounces of food ; in the second and third months, about twenty-four fluidounces, and from this time to the twelfth month, from two to two and a half or even three pints. After the twelfth month 346 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. the quantity depends upon whether additions be made to the diet or milk food be used exclusively. When the daily amount reach three pints the limit of the capacity of the stomach is usually attained, and the greater demand for nutriment, as growth advances month by month, must be met by adding to the strength of the food rather than by increasing its bulk. These two factors, strength and quan- tity, are intimately associated throughout the whole period of infancy, and in the earlier months a mere increase in the latter is not always sufficient to maintain the balance of nutrition. 3d. The object to be accomplished in the preparation of cows' milk is to make it resemble human milk as nearly as possible in chemical composition and physical properties. To do this, it is necessary to reduce the proportion of cream, to increase the proportion of sugar, and to overcome the tendency of the casein to coagulate into large, firm masses upon entering the stomach. Dilution with water is all that need be done to reduce the amount of casein to the proper level ; but as this lessens the quantity of fat below the normal standard, and still further diminishes the already insufficient sugar, it is essen- tial to add fat and sugar to the mixture of milk and water. Fat is best added in the form of cream, and of the sugars, either pure white loaf sugar or sugar of milk may be used, though the latter is preferable, as it is little apt to ferment and contains some of the salts of the milk which are of nutritive value. The risk of firm clotting may be anticipated by the addi- tion of an alkali, or a small quantity of some thickening substance, as barley-water, gelatine or one of the digestible farinaceous foods. Lime-water is the alkali usually selected. It acts by partially neutralizing the acid of the gastric THE GENERAL MANAGEMENT OF CHILDREN. 347 juice, so that the casein is coagulated gradually and in small masses, or passes, in great part unchanged, into the intestine to be there digested by the alkaline secretions. As it contains only half a grain of lime to the fluidounce, the desired result cannot be attained unless, at least, a third part of the milk mixture be lime-water. The quantity often used — one or two teaspoonfuls to the bottle of food — has no effect beyond neutralizing the natural acidity of the milk itself. When lime-water is constantly employed, it becomes quite an item of expense if procured from a drug shop ; this outlay is unnecessary, for it can be made quite as well in the nursery. Take a piece of unslaked lime as large as a walnut, drop it into two quarts of filtered water contained in an earthen vessel, stir thoroughly, allow to settle and use only from the top ; replacing the water and stirring as consumed. Instead of lime-water, from two to four grains of bicar- bonate of sodium may be added to each bottle, or, better still, from five to fifteen drops of the saccharated solution of lime. This solution, officinal in the British Pharmacopoeia, under the title of Liquor Calcis Saccharatus, is made in the following way : — Take of — Slaked Lime , 1 ounce. Refined Sugar, in powder, 2 ounces. Distilled Water, 1 pint. Mix the lime and sugar by trituration in a mortar. Transfer the mixture to a bottle containing the water, and having closed this with a cork, shake it oc- casionally for a few hours. Finally, separate the clear solution with a siphon, and keep it in a stoppered bottle. Thickening substances act purely mechanically by get- ting, as it were, between the particles of casein during coagulation, preventing them running together and forming large, compact masses. 348 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. Of these materials barley-water is perhaps the best. To prepare it, put two good teaspoonfuls of washed pearl barley, with a pint of cold filtered water into a saucepan, boil slowly down to two-thirds and strain. The liquid obtained does not possess the disadvantages of farinaceous foods generally. To be efficient, it must be used as a diluent in- stead of, and in the same proportions as, water. Gelatine is prepared in the following way : put a piece of plate gelatine, an inch square, into half a tumblerful of cold water, and let it stand for three hours ; then turn the whole into a teacup, place this in a saucepan half full of water and boil until the gelatine is dissolved. When cold this forms a jelly ; from one to two teaspoonfuls may be added to each bottle of milk-food. When an " infant's food " is used to act mechanically, care should be taken to select one in which the starch has been converted into dextrine and grape sugar by the pro- cess of manufacture. The article known as " Mellin's Food " can be relied upon. One teaspoonful of this dis- solved in a tablespoonful of hot water, and added to each portion of food, makes a very easily digested mixture. For the successful management of children, the practi- tioner must not only be familiar with the theory of feeding, but must be able to write out precise directions for the prepara- tion of the food. To this end a schedule of the diet of an infant from birth upward, with a sketch of the modifications that have to be made most frequently, will serve as a useful guide. Diet during the first week : — Cream, f ^ iij. Sugar of milk, gr. xv. Whey, f.fss, f^ij. Water, f^ss, f^ij. For each portion; to be given every two hours from 5 a.m. to 1 1 p.m., and in some cases once or twice at night. THE GENERAL MANAGEMENT OF CHILDREN. 349 To make whey, add three teaspoonfuls of wine of pepsin to a quart of warm fresh milk, and stand near the fire for two hours, then remove the curd by straining through muslin. Diet from the second to the fifth week : — Milk, fgss. Cream, f 3; ij. Sugar of milk, gr. xv. Water, fgj. For one portion; to be given every two hours from 5 A.M. to II P.M. Diet from the fifth week to the end of the second month : — Milk, fgj,f3ij. Cream, f^ ss. Sugar of milk, gr. xxx. Water, f^f^J- For each portion ; to be given every two hours. Diet during the third month : — Milk, f^ijss. Cream, f^ss. Sugar of milk, 3 j. Water, f^j. For each portion ; to be given every two and a half hours. Diet during the fourth and fifth months : — Milk, fgiijss. Cream, f^ ss > Sugar of milk, ^j. Water, fgj. For each portion ; to be given every three hours. Diet during the sixth month, six meals daily. Morning and mid-day bottles, each : — Milk, " fgivss. Cream, f J>ss. Mellin's Food, „ £j. Hot water, f ^j. Dissolve the Mellin's Food in the hot water, and add, with stirring, to the previously mixed milk and cream. 350 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. Other bottles, each : — Milk, . f^ivss. Cream, f % ss. Sugar of milk, ^j. Water, fgj. In the seventh month the Mellin's Food may be increased to two teaspoonfuls, and given three times daily. Throughout the eighth and ninth months five meals a day will be sufficient. First meal, at 7 a.m. : — Milk, f^vjss. Cream, f% ss. Sugar of milk, 3_j. Water, f-fj. Second meal, at 10.30 a.m. — Milk, cream and water in same proportion ; Mellin's Food, one tablespoonful. Third meal, at 2 p.m. — Same as second. Fourth meal, at 6 p.m. — Same as second. Fifth meal, at 10 p.m. — Same as first. Instead of Mellin's Food, a teaspoonful of " flour ball " may be added. To make this material, take a pound of good wheat flour — unbolted, if possible — tie it up very tightly in a strong pudding-bag, place it in a saucepan of water and boil constantly for ten hours; when cold, remove the cloth, cut away the soft, outer covering of dough that has been formed, and reduce the hard, baked interior by grating. In the yellowish-white powder obtained, almost all the starch has been converted into dextrine by the process of cooking, and the proportion of the nitrogenous principle to the calori- facient is as one to five, nearly the same as in human milk. Two meals of flour ball daily — say the second and fourth — are all that can be digested. To prepare these, rub one teaspoonful of the powder with a tablespoonful of milk into a smooth paste, then add a second tablespoonful of milk, con- THE GENERAL MANAGEMENT OF CHILDREN. 35 I stantly rubbing until a cream-like mixture is obtained; this is poured into eight ounces of hot milk, stirring well, and is then ready for use. The other meals should be composed of milk, cream, sugar of milk and water, as already given. Mellin's Food and flour ball may be substituted by any one of the "infants' foods" in which the starch has been converted into dextrine and grape-sugar, or by oat- meal or barley. A preparation of the latter, highly recom- mended by Eustace Smith, under the name of " barley jelly," is a digestible food. In making it, put two tablespoonfuls of washed pearl barley with a pint and a half of water and slowly boil down to a pint; next, strain out the barley and let the liquid set into a jelly. Two teaspoonfuls of this, dissolved in eight fluidounces of warmed and sweetened milk, are enough for a single feeding, and such a meal may be allowed twice a day. Diet for the tenth and eleventh months. First meal, 7 a.m. : — Milk, f^viijss. Cream, f^ ss. Mellin's Food, ^ ss. (Or flour ball or barley jelly, gij.) Water, f£j. (To be used only when Mellin's Food is employed.) Second meal, 10.30 a.m.— A breakfast-cupful of warm milk (foviij). Third meal, 2 p.m. — The yolk of an egg lightly boiled, with stale bread-crumbs. Fourth meal, 6 p.m. — Same as first. Fifth meal, 10 p.m. — Same as second. On alternate days, the third meal may consist of a tea- cupful (fovj) of beef-tea, containing a few stale bread-crumbs. Beef-tea for an infant is made in the following way : half a pound of fresh rump-steak, free from fat, is cut into small 352 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. pieces and put, with one pint of cold water, into a covered, tin saucepan. This must stand by the side of the fire for four hours, then be allowed to simmer gently (never boil) for two hours, and, finally, be thoroughly skimmed to remove all grease. A further variation can be made by occasionally using mutton, chicken or veal broths instead of beef-tea. As much more difficulty is experienced in feeding infants during the first twelve months than during the second, it will be well to pause here to consider what had best be done in case the food described should disagree. If after feeding, vomiting occur, with the expulsion of large, firm clots of casein, the effect of adding lime-water or barley-water must be tried. For instance, at the age of six weeks make each bottle of:— Milk, f£j.f3*J- Cream, f^ ss - Sugar of milk, 3 ss. Lime-water, f^j, f^ij. Or of:— Milk, f£j.fgij. Cream, f^ ss - Sugar of milk, g ss. Barley-water, f^j,f^ij. Sometimes, particularly if there be diarrhoea, boiling makes the milk more digestible, and in this condition it may be used instead of fresh milk in either of the above mixtures. Condensed milk, too, can be employed tempo- rarily, making each portion of — Condensed milk, f 3 j. Cream, f^ ss - Hot water, f i| ijss. Should further alteration be necessary, goats' or asses' milk may be substituted for cows' milk, the strong odor of THE GENERAL MANAGEMENT OF CHILDREN. 353 the former and the laxative properties of the latter being removed by boiling. "Strippings" is another good substitute for cows' milk. It is obtained by remilking the cow after the ordinary daily supply has been drawn, and contains much cream and but little curd. Assimilable proportions of this are : — Stoppings, f 3 j. Water, f^ij. And if the little casein in such a mixture be still un- digested : — Strippings, f^j ss « Barley-water, f^j ss - When, in spite of careful preparation, all of these foods give rise to indigestion, with fever, and the expulsion, by vomiting and diarrhoea, of hard curds from the stomach and intestines, the expedient of pre-digesting the milk must be resorted to. There are several ways of artificially digest- ing milk. One plan * is to add to each fluidounce of milk five grains of pure pepsin and four drops of dilute muriatic acid ; digest in a water-bath, at a temperature of ioo° F., until the mixture becomes clear, then neutralize with bi- carbonate of sodium and the milk is ready for use. The best method, and the one now almost uniformly adopted in this country, is to peptonize the milk by pan- creatin.f To accomplish this artificial digestion, put into a clean quart bottle five grains of extractum pancreatis, fifteen grains of bicarbonate of sodium, and four fluidounces of cool, filtered water ; shake thoroughly together, and add a pint of fresh, cool milk. Place the bottle in water so hot * Recommended by Eustace Smith. f That manufactured under the name of Extractum Pancreatis, by Fairchild Brothers & Foster, has proved most efficient in the author's hands. 23 354 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. that the whole hand can be held in it for a minute without discomfort, and keep the bottle there for exactly thirty- minutes. At the end of that time put the bottle on ice, to check further digestion and keep the milk from spoiling. The fluid obtained, while somewhat less white in color than milk, does not differ from it in taste ; if, however, an acid be added, the casein, instead of being coagulated into large, firm curds, takes the form of minute soft flakes, or readily broken down, feathery masses of small size. When the process is carried just to the point described, the casein is only partially converted into peptone, but every succeeding moment of continued warmth lessens the amount of casein, until peptonization is complete. Then the liquid is grayish-yellow in color, has a distinctly bitter taste, and shows no coagulation whatever on the addition of an acid. This artificial digestion, therefore, may be carried just as far as circumstances indicate, although it is ordi- narily best to stop it short of complete conversion, as children object to the markedly bitter taste and often, on account of it, absolutely refuse the food. Partial peptoniza- tion, too, is usually sufficient to adapt the milk to ready assimilation. To seize the proper moment for arresting the process, the person conducting it must be told to taste the milk from time to time, and as soon as the least bitter- ness is appreciable, to remove the bottle from the hot water and place it upon ice for cooling and use. Such milk may be sweetened with sugar of milk, and given pure or diluted with water. Thus, for an infant of six weeks, each meal may consist of: — Peptonized milk, fo"J- Sugar of milk, 3 ss. Water, fgj. To this cream may be added when desirable, and by THE GENERAL MANAGEMENT OF CHILDREN. 355 diminishing the quantity of water and increasing that of the milk the strength of the food may be made greater at any time. Although every precaution be taken, the last of a quantity of pre-digested food is very apt to grow bitter. And if the attendants will take the trouble, it is much better to peptonize every meal separately. This is readily done by ordering a number of powders of pancreatin and bicarbonate of sodium, so proportioned that each packet shall contain the proper amounts for one bottle of food. For example : — R . Ext. Pancreatis, gr. ix. Sodii Bicarb., gr. xxiv. M. et ft. chart, (waxed papers) No. xij. S. — Put one powder into a nursing bottle with two fluid- ounces of filtered water and two fluidounces of fresh, sweet milk ; shake together and keep warm in a water- bath for about half an hour before feeding ; sweeten with half a teaspoonful of milk sugar. The great advantages of partial peptonization are that the necessity for lime-water, barley-water and thickening substances to keep apart the curd, is done away with, and that, when the digestive disturbance, requiring a careful preparation of food, is removed, an ordinary milk diet can be gradually resumed, by regularly diminishing the time artificial digestion is allowed to progress. This changes the casein in a less and less degree, until finally it is taken in its natural form. Sometimes, milk in every form, and however carefully prepared, ferments soon after being swallowed and excites vomiting, or causes great flatulence and discomfort, while it affords little nourishment. With these cases, the best plan is to withhold milk entirely for a time and try some other form of food. The following are good substitutes : — 35^ DISEASES OF DIGESTIVE ORGANS IN CHILDREN. Mellin's Food, gj. Hot water, f^p\j- For each portion ; to be given every two hours at the age of six weeks. Veal broth* fg jss. Barley-water, f^j ss ' For one portion. Whey, f^j ss - Barley-water, f g jss. Sugar of milk, g ss. A teaspoonful of the juice of raw beef every two hours will usually be retained when everything else is rejected. Such foods are only to be used temporarily, until the tendency to fermentation within the alimentary canal ceases ; then milk may be gradually and cautiously resumed. When infants who are approaching the end of the first year become affected with indigestion, it is often sufficient to reduce the strength and quantity of the food to a point compatible with the digestive powers. For instance, at eight months the food may be reduced to that proper for a healthy child of six months, or even less. Here, too, pre- digestion of the food is most serviceable. If a few grains of extractum pancreatis be added to a gobletful of thick, well-boiled starch gruel, at a temperature of 100° F., the gelatinous mucilage quickly grows thinner and soon is transformed into a fluid, the starch having been rendered soluble by the action of the diastase contained in the pan- creatin ; by still longer contact the hydrated starch is converted into dextrine and sugar. Advantage may be taken of this property to render the foods containing starch assimilable. Thus, to a mixture of barley jelly and milk, e.g.:— * Veal broth is to be made of the strength of half a pound of meat to the pint. THE GENERAL MANAGEMENT OF CHILDREN. 357 Barley jelly, ^ij. Sugar of milk, gj. Warm milk, f% viij. Add three grains of extractum pancreatis, and five grains of bicarbonate of sodium, and keep warm for about half an hour before feeding. The same process may be employed with food containing oat-meal, arrowroot or wheaten flour, with the effect of con- verting the starchy elements into digestible products, and without materially altering the taste. When the infant has arrived at an age to take meat broths, these too may be readily peptonized when diges- tion is enfeebled. The recipe for peptonized beef-tea, which may be taken as an example, is : — To one-quarter of a pound of minced raw beef, entirely free from fat, add one-half pint of cold water; cook over a slow fire, with constant stirring, until it has boiled a few minutes. Then pour off the liquor and beat or rub the meat to a paste. Put the latter into a jar with one-half pint of cold water, and pour in the liquor previously obtained. Add to 'this mixture thirty grains of extractum pancreatis and twenty grains of bicarbonate of sodium, shake all well together, and keep at a temperature of about I io° F., stirring occasionally, for three hours. Next, boil quickly, strain, and serve as required. Returning to the regimen of the healthy infant, it will be found that, after the first year, far less change is re- quired in the food from month to month. Diet from the twelfth to the eighteenth month, five meals per day: — First meal, 7 a.m. — A slice of stale bread, broken and soaked in a breakfast-cup (foviij) of new milk. Second meal, 10 a.m. — A teacup of milk (f§vj), with a soda biscuit or thin slice of buttered bread. 358 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. Third meal, 2 p.m. — A teacupful of beef-tea (fSyj), with a slice of bread. One good tablespoonful of rice and milk pudding. Fourth meal, 6 p.m. — Same as first. Fifth meal, io p.m. — One tablespoonful of Mellin's Food with a breakfast-cupful of milk. To alternate with this : — First meal, 7 a.m. — The yolk of an egg, lightly boiled, with bread crumbs ; a teacupful of new milk. Second meal, 10 a.m. — A teacupful of milk with a thin slice of buttered bread. Third meal, 2 p.m. — A mashed boiled potato, moistened with four tablespoonfuls of beef-tea ; two good tablespoon- fuls of junket. Fourth meal, 6 p.m. — A breakfast-cupful of new milk, with a slice of bread broken up and soaked in it. Fifth meal, 10 p.m. — Same as second. The fifth meal is often unnecessary, and sleep should never be disturbed for it ; at the same time, should the child wake an hcur or more before the first meal, he must break his fast upon a cup of warm milk, and not be allowed to go hungry until the set breakfast hour. Diet from eighteen months to the end of two and one- half years, four meals a day : — First meal, 7 a.m. — A breakfast-cupful of new milk ; the yolk of an egg lightly boiled ; two thin slices of bread and butter. Second meal, 1 1 a.m. — A teacupful of milk with a soda biscuit. Third meal, 2 p.m. — A breakfast-cupful of beef-tea, mutton or chicken broth ; a thin slice of stale bread ; a saucer of rice-and-milk pudding. Fourth meal, 6.30 p.m. — A breakfast-cupful of milk with bread and butter. THE GENERAL MANAGEMENT OF CHILDREN. 359 On alternate days : — First meal, 7 a.m. — Two tablespoonfuls of thoroughly cooked oat-meal or wheaten grits with sugar and cream ; a teacupful of new milk. Second meal, 1 1 a.m. — A teacupful of milk with a slice of bread and butter. Third meal, 2 p.m. — One tablespoonful of underdone mutton pounded to a paste ; bread and butter, or a mashed baked potato, moistened with good, plain dish gravy ; a saucer of junket. Fourth meal, 6.30 p.m. — A breakfast-cupful of milk, a slice of soft milk toast, or a slice or two of bread and butter. When sickness supervenes, all that is ordinarily necessary is a reduction of the diet to plain milk, or milk with Mellin's Food. An important point often neglected is the matter of drink. Even the youngest infant requires water occasionally, and the demand increases with age. The water must be as pure as possible, and should not be too cold, although, in the heat of summer, bits of ice, and water moderately cooled by ice can be allowed without harm. The foregoing 'schedule must, of course, be regarded only as an average ; many children can bear nothing but milk food up to the age of two or even three years, and, provided enough be taken, no fear for their nutrition need be enter- tained. The rule to adopt is, if a child be thriving on milk, he is never to be forced to take additional food merely because a certain age has been reached; let the healthy appetite be the guide. 4th. Success in hand-feeding depends quite as much on the administration as upon the preparation of the food. From birth up to such time as broth, bread and eggs are added to the diet, all the food should be taken from a bottle ; 360 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. and even after this, as the bottle is a comfort and insures slow feeding, it may be allowed for milk preparations until the child, of his own accord, tires of it. The only feeding apparatus to be admitted to the nursery is the simple bottle and tip, represented in the accompanying figure ; all com- Fig. 6. — Feeding-Bottle and Tip. plicated arrangements of rubber and glass tubing are not only an abomination, but a fruitful source of sickness and death. Rather than use them, it is far better to feed the infant with a spoon. The bottle shaped as above must be of transparent flint glass, so that the slightest foulness can be detected at a glance, and may vary in capacity from six to twelve fluid- ounces, according to the age of the child. Two should be on hand at a time, to be used alternately. Immediately after THE GENERAL MANAGEMENT OF CHILDREN. 36 1 a meal, the bottle should be thoroughly washed out with scalding water, rilled with a solution of bicarbonate or sali- cylate of sodium — 5j of either to a pint of water — and thus allowed to stand until next required; then, the soda solution being emptied, it must be thoroughly rinsed with cold water before receiving the food. The tips or nipples, of which there should also be two, must be composed of soft, flexible India-rubber, and a conical shape is to be pre- ferred, as being more readily everted and cleaned ; the open- ing at the point must be free, but not large enough to permit the milk to flow in a stream without suction. At the end of each feeding, the nipple must be removed at once from the bottle, cleansed externally by rubbing with a stiff brush wet with cold water, everted and treated in the same way, and then placed in cold water and allowed to stand in a cool place until again wanted. While taking these precautions for perfect cleanliness, the nurse must satisfy herself of their efficacy by smelling both the bottle and tip just before they are used, to be sure of the absence of any sour odor. Next to cleanliness of the feeding apparatus, it is import- ant to insist upon the separate preparation of each meal immediately before it is to be given. The practice of mak- ing in the morning the whole day's supply of food, though it save trouble, is a most dangerous one. Changes almost invariably take place in the mixture, and by the close of the day it becomes unfit for consumption. A common glass graduate, marked for fluidrachms and ounces and holding a pint, should be provided for the nursery. Some moments before meal-time, so as to avoid hurry, the different fluid ingredients of the food are to be measured in this, one after the other ; the requisite quantity of milk-sugar is then added, and the whole mixed tho- 362 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. roughly by stirring with a spoon, and poured into the feeding-bottle. The food must now be heated to a temper- ature of about 95 F. This can be done by steeping the bottle in hot water, or by placing it in a water-bath, over an alcohol lamp or gas jet. Finally, the tip is applied and the meal is ready. When feeding, the child must occupy a half-reclining position in the nurse's lap. The bottle should be held by the nurse, at first horizontally, but gradually more and more tilted up as it is emptied, the object being to keep the neck always full, and prevent the drawing in and swallowing of air. Ample time, say five, ten or fifteen minutes, according to the quantity of food, should be allowed for a meal. It is best to withdraw the bottle occasionally for a brief rest, and after the meal is over, sucking upon the empty bottle must not be allowed, even for a moment. 5th. For children residing in cities an honest dairyman must be found, who will serve sound milk and cream from country cows, once every day in winter and twice a day during the heat of summer. Every cow is subject to changes in health, and the milk of ordinary stock cows is more suitable than that from Alderney or Durham breed, as the latter is too rich, and, therefore, more difficult to digest. The mixed milk of a good herd is to be pre- ferred to that from a single animal. It is less likely to be affected by peculiarities of feeding, and less liable to variation from alterations in health or different stages of lactation. The milk and cream must be transported from the dairy in perfectly clean vessels. To insure this it is best to pro- vide two sets of small cans, one set to be thoroughly cleansed and aired while the other is taken away by the milk-man to carry back the next supply. So soon as this THE GENERAL MANAGEMENT OF CHILDREN. 363 arrives in the morning, or in the morning and evening in hot weather, the cans should be emptied into separate and absolutely clean earthenware or glass pitchers, and these put at once into a refrigerator, reserved exclusively for them. This may stand in some convenient spot near the nursery, but not in it, and, especially, not in an adjoining bath-room. With a good refrigerator there is no difficulty in keeping the milk perfectly sweet for twenty-four hours in winter, and for twelve hours in summer, except on in- tensely hot days ; then it may be necessary to scald or lightly boil the whole of the supply when received, in order to prevent change. Children who have cut their milk teeth may be fed for a twelvemonth — namely, up to the age of three and a half years — in the following way : — First meal, 7 a.m. — One or two tumblerfuls of milk ; a saucer of thoroughly cooked oat-meal or wheaten grits, and a slice of bread and butter. Second meal, 1 1 a.m. (if hungry). — A tumblerful of milk or a teacupful of beef-tea, with a biscuit. Third meal, 2 p.m. — A slice of underdone roast beef or mutton, or a bit of roast chicken or turkey, minced as fine as possible ; a baked potato, thoroughly mashed with a fork and moistened with gravy; a slice of bread and butter ; a saucer of junket or rice-and-milk pudding. Fourth meal, 7 p.m. — A tumblerful of milk, and one or two slices of well-moistened milk toast. From three and a half years up the child must take his meals at the table with his parents, or with some reliable attendant, who will see that he eats leisurely. The diet, while plain, must be varied. The following list will give an idea of the food to be selected : — 364 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. BREAKFAST. Every day. One dish only each day. Milk. Fresh fish. Porridge and cream. Eggs, lightly boiled. Bread and butter. poached. scrambled, plain omelette. Chicken hash. Stewed kidney. Stewed liver. Sound fruits maybe allowed before or after the meal, according to taste, as oranges, grapes without pulp (seeds not to be swallowed), peaches, thoroughly ripe pears, cantaloupes and strawberries. DINNER. Every day. Two dishes each day. Clear soup. Potatoes, baked. Meat roasted or boiled mashed, and cut into small pieces. Spinach. Bread and butter. Stewed celery. Cauliflower. Hominy. Macaroni, plain. Peas. String-beans, young. Green corn, grated. Junket, rice-and-milk, or other light pudding, and, occasionally, ice cream, may be allowed for dessert. SUPPER. Every day. Milk. Milk toast or bread and butter. Stewed fruit. Fried food, highly seasoned or made up dishes, are to be excluded; no condiment but salt is to be used, and the formation of a habit of eating between meals must be avoided. Filtered or spring water should be the only drink ; tea, coffee, wine or beer being entirely forbidden. THE GENERAL MANAGEMENT OF CHILDREN. 365 As to quantity, a healthy child may be permitted to satisfy his appetite at each meal, under the one condition that he eats slowly and masticates thoroughly. In case of illness, the diet must be reduced in quantity and quality, according to the rules that are applicable to adults. 2. Bathing. During the first two and a half years of life a child ought to be bathed once every day. The bath should be given at a regular time, and it is best to select some hour in the early morning, midway between two meals — ten o'clock, for in- stance. The tub should be placed near the fire or in a warm room in winter, and away from currents of air in summer. It should contain enough water to cover the child up to the neck when in a sitting posture, and the temperature must be about 95 ° F. Upon undressing the child, the first step is to wet his head ; then he is to be plunged into the water and thoroughly washed with a soft rag or sponge, and pure, unscented castile soap. After remaining in the water from three to five minutes the surface must be well dried, and rubbed with a flannel cloth or soft towel ; then the body must be enveloped in a light blanket and the infant either returned to his crib to sleep, or kept in the lap for ten or fifteen minutes, until tho- roughly warm and rested, and finally dressed. If there be repugnance to the bath, the tub may be covered over with a blanket, and the child being placed upon it, may be slowly lowered into the water without seeing anything to excite his fears. In very hot weather, in addition to the morning full bath, the body may be sponged twice daily, with water, at a temperature of 90 F. ; this, contrary to what might be 366 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. expected, has a greater and more permanent cooling effect than bathing with cold water. After the third year, three baths a week are quite suffi- cient. An evening hour is now to be preferred, but the water must still be heated to 90 . About the tenth year cooler baths can be begun, from 72 to 75 being the proper temperature. The cold sponge or cold plunge is not admissible as a daily routine until youth is well advanced. The hot bath — 95 ° to 100° — is employed for various purposes, notably for a derivative action ; to cause diapho- resis, to relieve nervous irritability, and to promote sleep. Whether a full bath or merely a foot-bath be required, five minutes is a sufficient time for immersion; then, with or without drying, according to the degree of sweating desir- able, the whole body, or only the feet and legs in case of a foot-bath, must be enveloped in a blanket, and the child put to bed. To render these baths more stimulating, from a teaspoonful to a tablespoonful of mustard flour may be added, and the child held in the water until the arms of the nurse begin to tingle. It is important not to continue a hot bath too long, lest the primary stimulating effect be followed by de- pression. Cold baths, by shocking the system, first pro- duce depression ; but this is temporary, and is followed by reaction, during which the skin grows red, and the pulse becomes fuller and stronger. They have, therefore, a general stimulant and tonic action, promoting nutri- tion and giving tone to the body. On account of the shock, the extent of which depends directly upon the coldness of the water, these baths must be used with caution, and are not to be employed in very young or feeble subjects. THE GENERAL MANAGEMENT OF CHILDREN. 367 When giving a cold bath, the child must be stripped in a warm room, and thoroughly rubbed with the palm of the hand until the whole body, especially the spinal region, is warm ; he must then stand in a tub containing enough hot water to cover the feet, and be rapidly sponged with the cold water. The temperature of the latter must never be below 6o°, and the addition of half an ounce of sea-salt or a tablespoonful of concentrated sea-water to the gallon, renders it more stimulating and insures a complete reac- tion. After the sponging, the surface must be thoroughly and quickly dried with a soft towel and shampooed with the open hand until aglow. The cooled bath may be employed with advantage in extreme conditions of hyperpyrexia. The child is first immersed in water at 95 °, and this is gradually lowered to 70 by the addition of cold water, the process occupying from fifteen to thirty minutes. Various medicated baths are employed. Of these the most useful are : — The Mustard Bath. Take from two drachms to one ounce of powdered mustard ; hot water, two to four gallons. Derivative in form of foot-bath ; stimulant as general bath. Salt-Water Bath. Take two ounces of rock salt, or Tidman's sea-salt, or concentrated sea- water (best) ; water (hot or cold, according to season), four gallons. General bath, to be used every morning in chronic tuberculosis, scrofula, rickets and general debility. Bath to be followed by thorough rubbing of the surface, especially over the spine. Bran Bath. Take one pint of bran, tie up in a muslin bag, place in a quart of water, boil for an hour, squeeze bag thoroughly into the water ; add to four gallons of warm water. Useful in eczema and skin diseases. 368 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. Nitro- Muriatic Acid Bath. Take muriatic acid; one fluidrachm; nitric acid, two fluidrachms ; warm water, four gallons. Serviceable in hepatic sluggishness. Make bath in a wooden tub. May be employed as a foot or general bath. Mercurial Bath. R . Hydrarg. Chlorid. Corros., gr. v. Alcohol, f-^ij- Aq. Dest., f^j. M. S. — Add to four gallons of water. Employed in syphilitic skin diseases. Soda Bath. Take half an ounce of bicarbonate of sodium ; warm water, four gallons. Used in skin affections. Astringent Bath. Take one pound of oak bark, one quart of water, boil for half an hour, strain and add to four gallons of warm water. 3. Clothing. Infants and young children have little power of resisting cold, and on this account require warm clothing. Too much cannot be said in condemnation of the fashion of allowing children to go, even while in the house, with bare legs and knees. Every child is supplied with a certain amount of nerve force to be daily expended in the maintenance of the differ- ent functions of the body — respiration, circulation, diges- tion, calorification, etc. If an excessive proportion of this force be consumed in keeping up the heat of the body, as is the case when so much is left bare, the other functions, especially the digestive, must suffer in consequence. During the oppressive heat of summer, the legs may be left uncovered ; but throughout the rest of the year, the whole body must be encased in woolen underclothing. The THE GENERAL MANAGEMENT OF CHILDREN. 369 thickness of this must vary, of course, with the season.* Providing this be done, the outer clothing may be left to the taste of the mother; but all garments should fit loosely, that the functions of the different viscera may not be impeded by pressure. The best pattern of a winter night-dress is a long, plain slip, with a drawing-string at the bottom, to prevent exposure of the feet and limbs, should the child kick off the bed- covering. This should be made of flannel, or, the more easily washed, Canton flannel. In summer, a loose muslin one may be put on, without the drawing-string. A flannej. under-vest should always be worn at night, light gauze in summer and heavier wool in winter; care must be taken, however, to have one for night alone, discarding that worn in the daytime. In infants under a year old, a broad flannel abdominal bandage, extending from the hips well up to the thorax, or, better still, a knitted worsted band shaped to fit the form, is very useful in keeping the abdominal organs warm, aiding digestion, and preventing pain. All clothing should be changed sufficiently frequently to insure cleanliness. Shoes must be large, well shaped and made of soft leather, with pliable soles, so as to allow the feet to grow freely. When dressing a child for exercise in the open air in cold weather, the outer clothing must not be put on until just be- fore leaving the house, and removed immediately on return. It is important to protect the head from cold in winter by a close-fitting, thick cap; and from the direct rays of the sun in summer by a broad-brimmed, light straw hat. * Drawers, especially adapted for children wearing diapers, can be obtained of the Dress Reform Association. These are made in two pieces, that they may not become wet or soiled. 24 370 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. Rubber shoes are necessary in wet weather to keep the feet warm and dry while walking out of doors. 4. Sleep. For some time after birth, infants spend the intervals between being fed, washed and dressed in sleep, and thus pass fully eighteen out of the twenty-four hours. As age advances, the amount of sleep required becomes less, until at two years thirteen hours, and at three years eleven hours, are enough. Any marked diminution in the length of sleep or decided restlessness indicate disease, and demand atten- tion from the physician. This matter, though, is, perhaps, more a question of training than any other item of nursery regimen, and many a mother, by want of judicious firmness, has rendered the early years of her child's life not only a burden to himself, but an annoyance to the entire house- hold. One cannot too soon begin to form the good habit of regularity in sleeping hours, and so far as circumstances will admit, the following rules may be enforced : — From birth to the end of the sixth or eighth month, the infant must sleep from 1 1 p.m. to 5 a.m., and as many hours during the day as nature demands and the exigencies of feeding, washing and dressing will permit. From eight months to the end of two and a half years, a morning nap should be taken, from 12 m. to 1.30 or 2 p.m., the child being undressed and put to bed. The night's rest must begin at 7 p.m. If a late meal be required, the child can be taken up at about ten o'clock, but if past the age for this, he may sleep undisturbed until he wakes of his own accord, some time between 6 and 8 a.m. From two and a half to four years, an hour's sleep may or may not be taken in the morning, according to the dis- THE GENERAL MANAGEMENT OF CHILDREN. 37 I position of the subject; but in every case the bed must be occupied from 7.30 p.m. to six or seven o'clock on the fol- lowing morning. After the fourth year, few children will sleep in the day- time; they are ready for bed by 8 p.m., and should be allowed to sleep for ten hours or more. A later retiring hour than 9 p.m. ought not to be encour- aged until after the twelfth or fifteenth year. When feasible, different rooms should be used for the day nursery and the sleeping apartment. The latter should be large, airy, well ventilated, so situated as to be exposed for a certain period each day to the direct rays of the sun, and provided with an open fire-place — for wood, preferably — which serves for both heating and ventilating. It should contain a bed for the nurse and a crib for the child, and be without curtains, heavy hangings or superfluous furniture. A stationary washstand draining into a sewer is not to be permitted in the room, neither should it communicate with a bath-room. Soiled diapers or chamber utensils are to be removed at once, no matter what the time of night. The day nursery should have large windows, protected by blinds, and a southwestern exposure ; all other requisites, with the exception of beds, are the same as in the sleeping room. It is very convenient to have the two chambers adjoining, but capable of entire separation by a door, so that one may be thoroughly aired without chilling the other. This arrangement, too, renders it practicable, by standing the door open and raising the windows in the day nursery, to keep the dormitory cool in hot weather without exposing the child to currents of air. If an apartment has to be occupied during both the day and night, it must be vacated for half an hour or more in the evening and well aired before the child is put back to bed. 372 DISEASES OF DIGESTIVE ORGANS IN CHILDREN. The temperature of the rooms must be as uniform as possible, the proper degree of heat being from 68° to yo° F. The crib should have high sides, to prevent the child from falling out and injuring himself, and should be pro- vided with springs and a soft hair mattress, protected by a gum cloth, placed under a double sheet. The bed- clothes must be light in weight, while varying in warmth according to the weather; it is just as important to insist upon cleanliness here as in the clothing of the body. 5. Exercise. A certain amount of muscular exercise is necessary for development and for the proper performance of the digestive functions. Infants, before they are able to stand, will use their muscles sufficiently if, when loosely clad, they are placed upon their backs in a bed and allowed to kick and turn about at pleasure. After the age of nine or ten months, a healthy child will begin to creep ; at the end of a year, he will make efforts at standing, and from four to eight months later, will be able to walk by himself; children, how- ever, present great differences in this respect, and a delay of a few months must not be considered as abnormal. So soon as efforts at creeping are made, there need be no fear that insufficient exercise will be taken; the care should be rather to prevent over-fatigue. Fresh air and sun-light are as necessary as muscular exercise. The child must be taken out of doors every day, weather permitting, after arriving at the proper age ; this is four months for children born in the early fall and winter, and one month for those born in summer. In cool weather, babies who are unable to walk should be taken out in a coach, or in the nurse's arms, for an hour in the morning and half an hour in the afternoon, while the THE GENERAL MANAGEMENT OF CHILDREN. 373 sun is shining. In summer, they may pass the greater part of the waking hours in the open air, provided they be well protected from the direct rays of the sun. Children old enough to walk may spend a longer time in the air in winter, and may be out all day in summer. But until the fourth year, it is better to let them play about at will than take a long set walk. Until well advanced in childhood, the house is the safest place in damp and rainy weather, when there is a strong east or north wind blowing, and when the thermometer stands below 15 . INDEX. Abdomen, examination of, 44. Abnormal dentition, 87. depression of temperature, 41. Abscess of liver, 298. retropharyngeal, 119. Absorption of fat, 43. Accelerated breathing, 36. Accumulation, faecal, 47. Acute gastric catarrh, 122-125. intestinal catarrh, 152-160. Affections of the gastro-intestinal mu- cous membrane, tongue in, 57. of the mouth and throat, 59. of the stomach and intestines, 12-2. Age in etiology of aphthous stomatitis, 62. of entero-colitis, 162. of gangrenous stomatitis, 73. of parasitic stomatitis, 79. of stomatitis, 60. of ulcerative stomatitis, 67. Alae nasi, dilatation of, 22. of nose, thick, 23. Alar chest, 49. Alterations of percussion sound, 55. of pulse, 39. Amyloid liver, 287-290. Anaemia, 41. Anaemic children, irregularity of pulse in > 39- Anatomical lesions of acute gastric ca- tarrh, 123. of aphthous stomatitis, 62. of catarrhal stomatitis, 59. of simple pharyngitis, 103. of ulcerative stomatitis, 67. Anterior fontanelle, 43. Aphthae, 57, 62. Aphthous stomatitis, 62-67. Ascaris lumbricoides, 249. Ascites, 322-327. Asthma, 37. Atrophy, 41. a result of difficult dentition, 91 general, skin in, 44. simple, 211. Attendants, questioning the, 18. Auscultation, 50. B. Barrel-shaped abdomen, 46. chest, 49. Bathing, 365-368. Beef tape-worm, 251. Bilious habit, 285. Bladder, distension of, 46. Blood in stools, 31. Blueness of face, 27. of finger nails, 27. Brain, irregularity of pulse in, 39. Brazen cough, 30. cry, 29. Breathing, accelerated, 36. difficult, 37. diminished frequency of, 36. labored, 37. puerile, 50. tidal, 7,6. Broadness of bridge of nose, 24. Bronchial catarrh, 37. Brows, contraction of, 22. Bulging of fontanelle, 43. Cardiac dulness, position of, 54. oedema, 44. sounds, 52. Caseation of the mesenteric glands, 45. Caseous degeneration and tuberculosis of the mesenteric glands, 266- 274. Catarrh, bronchial, 30. Catarrhal jaundice, 280. stomatitis, 59-61. 375 376 INDEX. Cessation of respiratory movements, 49. Cestodes, 248. Cheek, circumscribed flush on, 27. Chest, examination of, 47. Chewing motions of jaw, 22. Cheyne-Stokes' respiration, 36. Child, inspecting the, 21. Choked cough, 30. Cholera infantum, 41, 47, 1 88-194. Chorea, 26. Chronic diarrhoea, 161. entero- colitis, 161-175. gastric catarrh, 126-135. hydrocephalus, 24, 43. intestinal catarrh, 161-175. intussusception, 240. vomiting, 126. Circumscribed flush on cheek, 27. peritonitis, 46. Cirrhosis of the liver, 292-297. Clay-colored stools, 31. Clonic contraction of the muscles, 26. Closure of the anterior fontanelle, 43. Clothing, 368-370. in chronic gastric catarrh, 134. Clubbing of finger tips, 27. Coarse hair, 23. Colic, 26, 82, 201-204. Collapse, 41. skin in, 44. Collection of gas, 46. Commencing hip-joint disease, 42. Complexion, doughy, 23. Conditions of the skin, 43. Confluent aphthous stomatitis, 64. Congestion of the liver, 281-285. Conjunctivae, yellow hue of, 27. Conjunctival blenorrhcea during den- tition, 89. Constipation, habitual, 205. in habitual indigestion, 139. Constitutional syphilis, 24, 43. Contraction of the brows, 22. Convulsion, a, 26. Convulsions during dentition, 100. in chronic diarrhoea, 165. Cough, 30. Course of catarrhal stomatitis, 60. Croupous pneumonia, signs of, 50. Crusta lactea, 95. Cry from intestinal pain, 29. Cry, hydrencephalic, 29. in pleuritis, 29. the, 28. Crying, incessant, 29. while coughing, 29. Cyanosis of hand, 27. Cysticercus cellulosse, 253. D. Death agony, 41. Deformity of the nails, 27. Degree of elevation of the temperature, 40. Delayed dentition, 58, 87. Delay in walking, 42. Delicate features, 23. Dental paralysis, 102. Dentition, 86-103. irregular and faulty, 58. Depression of anterior fontanelle, 43. Description of aphthous stomatitis, 62. of catarrhal stomatitis, 59. of eczema, 93. of follicular tonsillitis, 108. of gangrenous stomatitis, 72. of parasitic stomatitis, 79. of simple pharyngitis, 103. of suppurative tonsillitis, 1 12. of ulcerative stomatitis, 67. Diagnosis of acute gastric catarrh, 124. of acute intestinal catarrh, 156. of amyloid liver, 288. of aphthous stomatitis, 64. of ascites, 324. of cholera infantum, 191. of chronic entero-colitis, 167. gastric catarrh, 130. of cirrhosis of the liver, 296. of dysentery, 196. of entero-colitis, 180. of fatty infiltration of the liver, 286. of follicular tonsillitis, no. of gangrenous stomatitis, 76. of habitual constipation, 206. indigestion, 140. of intussusception, 240. of mucous disease, 144. of parasitic stomatitis, 8^. of peritonitis, 311. of perityphlitis, 225. INDEX. 377 Diagnosis of simple atrophy, 217. pharyngitis, 105. of suppurative tonsillitis, 114. of syphilitic inflammation of the liver, 291. of tabes mesenterica, 270. of tubercular peritonitis, 319. of typhlitis, 225. of ulcerative stomatitis, 70. of worms, 257. Diagram of the eruption of the milk teeth, 86. Diarrhoea, chronic, 161. inflammatory, 175. loss of fat in, 43. simple, 152. during dentition, 90. Diathesis, strumous, 23. Diet for ascites, 326. for chronic gastro-intestinal catarrh, 146. for tabes mesenterica, 272. for tubercular peritonitis, 320. for ulcerative stomatitis, 70. Differential diagnosis of aphthous and parasitic stomatitis, 83. of aphthous and ulcerative stomatitis, 64. of chronic entero colitis and tuberculous diarrhoea, 167. of chronic gastric catarrh and tubercular meningitis, 131. of follicular tonsillitis and diphtheria, no. of gangrenous and ulcerative stomatitis, 76. of gangrenous stomatitis and malignant pustule, 77. of intussusception and dysen- tery, 241. of intussusception and faecal accumulation, 241. of intussusception and perfo- rative peritonitis, 241. of intussusception and simple colic, 241. of intussusception and typh- litis, 226. of simple pharyngitis and diphtheria, 105. Differential diagnosis of simple pharyn- gitis and scarlatinal pharyn- gitis, 105. of thrush and aphthous stoma- titis, 64. of tubercular peritonitis and typhoid fever, 320. of typhoid fever and tubercu- lar peritonitis, 320. Difficult breathing, 37. dentition, 88. Dilatation of alas nasi, 22. Diminished frequency of breathing, 36. Diminution of rate of pulse, 39. Discoloration of forehead, 27. Disease, features of, 21. investigation of, 17. of heart, 41. Diseases of the lungs, 41. Distension, drum-like, of the abdomen, 46. of abdomen, 45. of bladder, 46. Doughy complexion, 23. Drawing of upper lip, 22. Drum-like distension of the abdomen, 46. Dryness of the skin, 44. Dulness of the liver, 46. Duration of aphthous stomatitis, 64. of catarrhal stomatitis, 64. of elevation of temperature, 40. of parasitic stomatitis, 81. of red gum, 93. of simple pharyngitis, 104. of ulcerative stomatitis, 70. of white gum, 93. Dysentery, 47, 194-198. Dyspnoea, expiratory, 37. in hypertrophy of the tonsils, 1 17. inspiratory, 37. Earache, 29. Earthy tinge of face, 27. Eczema, 93. Effusion of pleurisy, 49. Egg of ascaris lumbricoides, 249. of oxyuris vermicularis, 249. of toenia saginata, 251. 378 INDEX. Egg of tricocephalus dispar, 250. Elevation of temperature, 40. Emphysema, chest in, 49. signs of, 50. Emphysematous air vesicles, 37. En chien de fusil, 25. Enema for convulsions, 101. for habitual constipation, 206. Enlarged spleen, 46. Enlargement of left ventricle, 49. of liver, 46. of right ventricle, 49. of spleen, 46. of superficial abdominal veins, 43. of superficial lymphatic glands, 44. Enteritis follicular, 47. Entero-colitis, 41, 175-188. stools of, 32. Eruptions, 44. on palate and fauces, 57. Etiology of acute intestinal catarrh, of amyloid liver, 287. of aphthous stomatitis, 52. of ascites, 322. of catarrhal stomatitis, 59. of cholera infantum, 189. of chronic entero-colitis, 161. of chronic gastric catarrh, 126. of cirrhosis of the liver, 294. of colic, 201. of congestion of the liver, 282. of dysentery, 195, of entero-colitis, 176. of fatty degeneration of the liver, 286. of fatty infiltration of the liver, 285. of follicular tonsillitis, 108. of gangrenous stomatitis, 73. of habitual constipation, 205. of habitual indigestion, 136. of hypertrophy of the tonsils, 116. of intussusception, 234. of mucous disease, 141. of parasitic stomatitis, 79. of peritonitis, 307. of perityphlitis, 222. of simple atrophy, 211. of simple pharyngitis, 103. of tabes mesenterica, 267. Etiology of tubercular peritonitis, 316. of tubercular ulceration of the in- testines, 199. of typhlitis, 222. of ulcerative stomatitis, 67. Examination of chest, 47. of mouth and fauces, 55. physical, 35. Exanthemata in chronic diarrhoea, 165. skin in, 44. Excessive moisture of the skin, 44. Exercise, 372, 373. Expiratory dyspnoea, 37. respiration, 36. Eyeballs, oscillation of, 22. Eyelashes, long and curving, 23. Eyelids, lividity of, 27. puffiness of, 23. reddened, 23. Face, blueness of, 27. earthy tinge of, 27. lesions of eruptive fevers on, 27. lower third of, 22. middle third of, 22. oval, 23. round and heavy, 23. the, 21. upper third of, 22. Facies in parasitic stomatitis, 8^. Faecal accumulation, 46. evacuations, 30. Fat, absorption of, 43. Fatty infiltration of the liver, 285. liver, 285, 286. Fauces, examination of, 55. the, 57. Features, delicate, 23. of disease, 21. Febrile oscillations, 40. state, frequency of pulse in, 39. skin in, 44. Feeding, 329-365. in aphthous stomatitis, 64. Fever, 40. tongue in, 57. Fine hair, 23. INDEX. 379 Finger ends, glossy, in scarlatinal ne- phritis, 27. nails, blueness of, 27. tips, clubbing of, 27. Flat chest, 49. Flatulence, 45. Follicular enteritis, 47. tonsillitis, 108-m. Fontanelle, anterior, 43. Food for chronic gastric catarrh, 132. Forehead, discoloration of, 27. Formula? for food in chronic entero- colitis, 169. in colic, 203. in entero-colitis, 183. in habitual constipation, 208. in infancy, 157. Fremitus, vocal, 52. Frequency of pulse, ^8. Fretful crying, 29. Friction sound of pleuritis, 50. Fulness of bridge of the nose, 23. Furrow, genal, 23. labial, 23. nasal, 23. oculo-zygomatic, 22. Gangrene, 70. of mouth, 57. Gangrenous stomatitis, 72-79. Gas, collections of, 46. Gastric tympany, 54. Genal furrow, 23. General atrophy, skin in, 44. debility, 42. management of children, 329-373. peritonitis, 46. Gestures, 25. Glazed tongue, 142. Globular head, 24. Glossy finger ends, 27. Grave pyrexia, 40. Gross differences in temperature, 41. Growth of child, 41. H. Habitual constipation, 205-2: Hair, coarse, 23. fine, 23. Hand, cyanosis of, 27. Hard palate, 57. Head, globular, 24. square, 24. Heart, irregularity of, 39. oedema in affections of, 44. Flemorrhage, 41. Hepatic oedema, 44. Hepatitis, suppurative, 298. Herpetic vesicles on lips, 27. High-colored urine, ^. Hip-joint disease, 42. Hoarse cough, 30. Hoarseness, 29. Hunger, 29. Hydrencephalic cry, 29. Hydrocephalus, 43. chronic, 24. Hypostatic pneumonia, 165. Icterus, 275. in older children, 280. neonatorum, 276. Idiopathic acute gastric catarrh, 123. Imperfect digestion, stools of, 31. Impulse in emphysema, 49. Inaudible cry, 29. Incessant crying, 29. Incomplete closure of the lids, 21. Increased frequency of the pulse, 39. heat, 41. Indigestion, habitual, 136. stools of, 31. Infantile paralysis, 42. Inflammation of the colon and rectum. 194-198. of the lungs or pleura, 27. of the mouth, 57. Inflammatory diarrhoea, 175. Inherited syphilis, 27. Inspection of the abdomen, 45. of the chest, 48. Inspiratory dyspnoea, ^7- Insufficient nourishment, 41. Intensity of puerile breathing, 50. Intestinal catarrh, chronic, 1 61. stools of, 31. pain, cry of, 29. worms, 248-265. 38o INDEX. Introduction, 17-58. Intussusception, 230-247. Invagination, 230. Investigation of disease, 17. Irregular appearance of teeth, 88. dentition, 58. Irregularity of pulse, 38. Irritability of pulse, 38. J- Jadelot's furrows, 22. Jaundice, 27, 275-281. diminution of rate of pulse in, 39. Jerky movements, 26. Joints, swelling of, 44. K. Kidneys, cedema in affections of, 44. Labial furrow, 23. Labored breathing, 37. Lancing the gums, 102. Laryngeal obstruction, 37. Left ventricle, enlargement of, 49. Length of child at birth, 41. Lesions, anatomical, of aphthous sto- matitis, 62. of catarrhal stomatitis, 59. of eruptive fevers on face, 27. of ulcerative stomatitis, 67. Lice in eczema, 95. Lids, incomplete closure of, 21. twitching of, 22. Lips, herpetic vesicles on, 27. lividity of, 27. pursing out of, 22. upper, drawing of, 22. upper, swollen, 23. Liver, 45. abscess of, 298. amyloid, 287. cancer of, 305. cirrhosis of, 292. congestion of, 281. dulness, 46, 54. enlargement of, 46. fatty, 285. hy dated disease of, 305. Liver, cedema in affections of, 44. syphilitic inflammation of, 291. tuberculosis of, 305. Lividity of eyelids and lip, 27. Local affections in difficult dentition, 88. Localized distension of abdomen, 46. Lower third of face, 22. Lumbrici, 250. Lungs, inflammation of, 27. Lymphatic glands, enlargement of, 44. M. Malarial fevers, 27. Management of children, 329. Marasmus, 211. a result of difficult dentition, 91. skin in, 44. Meningitis tubercular, 47. Mesenteric glands, caseation of, 45. caseous degeneration of, 266. tuberculosis of, 266. Micturition, painful, t,t,. Middle third of face, 22. Milk teeth, 56. Moderate pyrexia, 40. Modifications of skin in disease, 43. Morbid anatomy of amyloid liver, 287. of cholera infantum, 188. of chronic entero- colitis, 161. of chronic gastric catarrh, 126. of cirrhosis of the liver, 293. of congestion of the liver, 282. of dysentery, 194. of entero-colitis, 175. of fatty degeneration of the liver, 286. of fatty infiltration of the liver, 285. of gangrenous stomatitis, 75. of intussusception, 231. of parasitic stomatitis, 80. of peritonitis, 306. of perityphlitis, 220. of simple atrophy, 211. of suppurative tonsillitis, 112. of syphilitic inflammation of the liver, 291. INDEX. 381 Morbid anatomy of tabes mesenterica, 266. of tubercular peritonitis, 315. of tubercular ulceration of the intestines, 199. of typhlitis, 220. Morbus caeruieus, 27. Motor paralysis, 26. Mouth, contraction of muscles about the, 22. examination of, 55. in catarrhal stomatitis, 61. Movements, jerky, 26. Mucous disease, 140. skin in, 43. membrane, oral, 55. Mucus, vomiting of, 34. Muscles, clonic contraction of, 26. wasting of, 43. Mustard foot-bath, 106. N. Nails, deformity of, 27. redness about, 27. Nasal cry, 29. furrow, 23. Nematodes, 248. Nephritis, diminution of rate of pulse in, 39- Nervous children, irregularity of pulse in, 39- Noma, 72-79. Non-inflammatory diarrhoea, 152. Nose, bridge of, broadness of, 24. fulness of bridge, 23. rubbing the, 26. Nostrils, sharpness of, 22. wide, 23. Obstruction, laryngeal, 37. Oculo- zygomatic furrow, 22. GEdema, 44. Offensive stools, 32. Oidium albicans, 79. Oral mucous membrane, 55. respiration, 37. Oscillation of eyeballs, 22. of temperature, 40. Otitis during dentition, 90. Oval face, 23. Oxyuris vermicularis, 248. Painful micturition, 2>3- Pain in habitual indigestion, 139. Palate, the, 57. Paleness, 27. Pallor, waxy, 27. Palpation of the abdomen, 44. of the chest, 52. Paralysis, dental, 102. infantile, 42. Parasitic stomatitis, 79-85. Parenchymatous nephritis, diminution of rate of pulse in, 39. Paroxysmal cough, 30. Pathognomonic sign of caseation of the mesenteric glands, 45. Pathology of gangrenous stomatitis, 75. Percussion of the abdomen, 44. of the chest, 53. over enlarged mesenteric glands, 46. Peritonitis, 306-314. circumscribed, 46. general, 46. tubercular, 314. Perityphlitis, 220-230. Permanent teeth, 56. Pharyngitis, simple, 103. Pharynx, the, 57. Photophobia, 25. Physical examination, 35. Pitch in puerile breathing, 5 1 . Plan of conducting investigation of dis- ease, 18. Pleura, inflammation of, 27. Pleurisy, effusion of, 49. Pleuritis, chest in, 49. cry in, 29. friction sound of, 50. Pneumonia, 27, 29. breathing in, 36. Pork tape- worm, 251. Position of apex beat, 49. of cardiac dulness, 54. Prsecordial dulness, 55. Premature appearance of the teeth, 87. 382 INDEX. Prescription for acute gastric catarrh, 124. for amyloid liver, 289. for aphthous stomatitis, 66. for ascites, 325. for catarrhal stomatitis, 61. for cholera infantum, 193. for chronic entero-colitis, 172. for chronic gastric catarrh, 135. for chronic gastro-intestinal catarrh, 149. for cirrhosis of the liver, 297. for colic, 203. for dysentery, 197. for eczema, 96, 100. for entero-colitis, 184. for follicular tonsillitis, no. for habitual constipation, 209. for hypertrophy of the tonsils, 1 18. for intussusception, 243. for parasitic stomatitis, 85. for peritonitis, 314. for prevention of perityphlitis, 227. for prevention of typhlitis, 227. for simple pharyngitis, 106. for suppurative tonsillitis, 115. for syphilitic inflammation of the liver, 292. for tubercular peritonitis, 321. for tubercular ulceration of the in- testines, 200. for ulcerative stomatitis, 71. for urticaria, 92. for vomiting during dentition, 91. for worms, 258. Prognosis of acute gastric catarrh, 124. of acute intestinal catarrh, 156. of amyloid liver, 289. of ascites, 325. of cholera infantum, 192. of chronic entero-colitis, 167. of chronic gastric catarrh, 131. of cirrhosis of liver, 296. of congestion of liver, 284. of dysentery, 196. of entero-colitis, 181. of fatty infiltration of the liver, 286. of follicular tonsillitis, no. of gangrenous stomatitis, 77. of habitual constipation, 206. of habitual indigestion, 140. Prognosis of intussusception, 242. of mucous disease, 145. of parasitic stomatitis, 83. of peritonitis, 313. of perityphlitis, 226. of simple atrophy, 218. of syphilitic inflammation of the liver, 291. of tabes mesenterica, 271. of tubercular peritonitis, 320. of typhlitis, 226. of ulcerative stomatitis, 70. of worms, 257. Prognostic value of frequency of the pulse, 39. Prolonged rise of temperature, 40. Prophylaxis in gangrenous stomatitis, 78. Prostration of vital forces, skin in, 44. Protracted diarrhoea, loss of fat in, 43. Puerile breathing, 50. Puffiness of eyelids, 23. Pulsation, transmitted epigastric, 49. Pulse, 38. frequency of, 38. irregularity of, 38. Pursing out of lips, 22. Pyrexia, 40. Q. Questioning attendants, 18. R. Rachitic softening of the ribs, 49. Range of oscillations of temperature, 40. Rapid rise of temperature, 40. Rash, tooth, 93. Rattling cough, 30. Reddened eyelids, 23. Red gum, 93. Redness about the nails, 27. Reduction of temperature, 41. Remission of temperature, 41. Renal diseases, pallor in, 27. oedema, 44. Resonance, vocal, 52. Respiration, 35. Cheyne-Stokes', 36. expiratory, 36. INDEX. 383 Respiration, oral, 37. puerile, 51. Respiratory movements, cessation of, 49. Retarded closure of the anterior fonta- nelle, 43. Retraction of the abdomen, 45. of the chest, 49. Retropharyngeal abscess, 119-121. Rheumatism, 44. Rhythm in puerile breathing, 51. of the pulse, 39. Rickets, 24, 43. thorax in, 49. Right ventricle, enlargement of, 49. Rises of temperature, 40. Round face, 23. Round worm, 248. Rubbing of nose, 26. Scaphoid abdomen, 47. Sclerotic, pearly white or bluish, 23. Scolex, 252. Scrofula, 44. Second summer, 88. Serous effusions in chronic entero-coli- tis, 165. Severe pyrexia, 40. Shape of chest, 48. Sharpness of the nostrils, 22. Signs of croupous pneumonia, 50. of emphysema, 50. Simple atrophy, 211-220. diarrhoea, 152. during dentition, 90. pharyngitis, 103-107. Sinking of anterior fontanelle, 43. Skin, conditions of the, 43. of healthy child, 26. smooth and transparent, 23. yellow hue of, 27. Sleep, 25, 370-372. Slight spasms during dentition, 100. Smoky urine, 33. Smooth and transparent skin, 23. Snuffling, 37. Soft palate, 57. Sour liquid, vomiting of, 34. Spasmodic cough, 30. Spasms during dentition, 100. Spleen, the, 45. enlargement of, 46. Splenic dulness, 54. Spurious hydrocephalus, 130. Square head, 24. Squinting, 22. Stomatitis, aphthous, 62. aphthous, confluent, 64. catarrhal, 59. gangrenous, 72. parasitic, 79. ulcerative, 67. Stools in chronic entero-colitis, 162. Strophulus, 92. Strumous diathesis, 23. Sudden fall of temperature, 40. Superficial catarrh of the tonsils, 107, 108. Suppressed cough, 30. Suppurative hepatitis, 298-305. tonsillitis, 112-119. Swelling of joints, 44. Swollen upper lip, 23. Sympathetic effects of difficult denti- tion, 89. Symptoms of acute gastric catarrh, 123. of acute intestinal catarrh, 154. of amyloid liver, 287. of aphthous stomatitis, 62. of ascites, 322. of catarrhal stomatitis, 60. of cholera infantum, 189. of chronic entero-colitis, 162. of chronic gastric catarrh, 128. of cirrhosis of the liver, 294. of colic, 202. of congestion of the liver, 282. of dysentery, 195. of eczema, 94. of entero-colitis, 178. of fatty infiltration of the liver, 285. of follicular tonsillitis, 108. of gangrenous stomatitis, 73. of habitual constipation, 205. of habitual indigestion, 138. of hypertrophy of the tonsils, 116. of intussusception, 235. of mucous disease, 141. of parasitic stomatitis, 81. 3^4 INDEX. Symptoms of peritonitis, 307. of perityphlitis, 223. of retropharyngeal abscess, 120. of simple atrophy, 214. of simple pharyngitis, 103. of suppurative tonsillitis, 112. of syphilitic inflammation of the liver, 291. of tabes mesenterica, 268. of tubercular peritonitis, 316. of tubercular ulceration of the in- testines, 200. of typhlitis, 223. of ulcerative stomatitis, 68. of worms, 254. Syphilis, constitutional, 24, 43. inherited, 27. Syphilitic inflammation of the liver, 291, 292. Systemic exhaustion, 43. weakness, 42. Tabes mesenterica, 266-274. Taenia;, 251. Taenia saginata, 251. Taenia solium, 253. Tears, 30. Teeth, 86. milk, 56. permanent, 56. Temperature in simple pharyngitis, 104. the, 39. Tendency, tuberculous, 23. Tenderness of abdomen, 47. Thallus, fibrils, 83. Thick alae of the nose, 23. Thorax in rickets, 49. Thread-worm, 248. Thrombosis of sinuses of the brain in chronic diarrhoea, 165. Thrush, 79-85. patches, 81. Thumbs drawn into palms, 26. Tidal breathing, 36. Tongue in mucous disease, 142. in ulcerative stomatitis, 69. the, 56. Tonsillitis, follicular, 108. suppurative, 112. Tonsils, hypertrophy of, 1 16. superficial catarrh of, 107. Tooth rash, 93. Transient rise of temperature, 40. Transmitted epigastric pain, 49. Treatment of acute gastric catarrh, 124. of acute intestinal catarrh, 156. of amyloid liver, 289. of aphthous stomatitis, 64. of ascites, 325. of catarrhal stomatitis, 61. of cholera infantum, 192. of chronic entero-colitis, 168. of chronic gastric catarrh, 131. of cirrhosis of the liver, 296. of colic, 202. of congestion of the liver, 284. of convulsions during dentition, 101. of dental paralysis, 102. of dysentery, 196. of eczema, 96. of entero-colitis, 181. of fatty infiltration of the liver, 286. of follicular tonsillitis, no. of gangrenous stomatitis, 77. of habitual constipation, 206. of hypertrophy of the tonsils, 117. of icterus in older children, 281. of intussusception, 242. of jaundice, 277. of mucous disease, 145. of parasitic stomatitis, 84. of peritonitis, 313. of perityphlitis, 227. of retropharyngeal abscess, 121. of simple atrophy, 218. of simple pharyngitis, 105. of spasms, 100. of strophulus, 93. of suppurative tonsillitis, 1 14. of syphilitic inflammation of the liver, 292. of tabes mesenterica, 272. of tubercular peritonitis, 320. of tubercular ulceration of the in- testines, 200. of typhlitis, 227. of ulcerative stomatitis, 70. of urticaria, 92. of worms, 257. INDEX. 385 Tricocephalus dispar, 250. Tubercular meningitis, 47. peritonitis, 314-322. ulceration of the intestines, 19S- 201. Tuberculosis of the intestines, skin in, 43. of the mesenteric glands, 266. Tuberculous diathesis, chest of, 49. tendency, 23. Twitching of lids, 21. Typhlitis, 220-230. u. Ulceration of fraenum linguae, 88. of intestines, stools of, 32. of mouth, 57. Ulcerative stomatitis, 67-72. Ulcers, aphthous, 63. of tubercular ulceration of the- in- testines, 199. Unwillingness to cry, 30. Upper third of face, 22. Urine, the, 32. Urticaria, 92. Uvula, the, 57. Variations of temperature, 40. Ventricles, enlargement of, 49. I Visible temporal veins, 23. \ Vocal fremitus, 52. resonance, 52. Vomiting, 33. during dentition, 93. in parasitic stomatitis, 82. loss of fat in, 43. w. Walking age, 42. on toes, 42. Wasting of muscles, 43. Watery stools, 31. Waxy pallor, 27. Weight of child at birth, 42. Wet-nurse, 86. Whip- worm, 250. White gum, 93. Wide nostrils, 23. Worm-eaten tongue, 142. Worms, 248. in stools, 32. in vomit, 34. Y. Yawning, 37. Yellow hue of skin and conjunctiva?, 27. 33 1 1 mi ■ MB ISKm #&:£# HL ■H _JHfl "■ '» 5?* ■ ran