. ■ CC « : or«c< <:ck cr ^ ...... ^c v.^^ ««: c ^^^ ^ X <» 3i C *BdS' c - " .ce. ^ rf^r*^ ^Sg ^^f^Co <<•' "<3 KJ^C*C : - C<3S^CC<« ^ ro -ac<«« eC *r?. '■ c C : Entered according to Act of Congress, in the year 1868, by HENRY C. LEA, in the Clerk's Office of the District Court of the United States in and for the Eastern District of Pennsylvania, PHILADELPHIA : COLLIXS, PRINTER, 705 JAYXE STREET. TO N. CHAPMAN, M.D., PROFESSOR OF THE INSTITUTES AND PRACTICE OF MEDICINE AND CLINICAL PRACTICE IN THE ETC. ETC. WHOSE TALENTS AND URBANITY HAVE RAISED HIM TO THE FIRST RANK IN THE PROFESSION, AND HAVE ACQUIRED FOR HIM THE CONFIDENCE AND ESTEEM OF A LARGE AND ENLIGHTENED COMMUNITY, THIS WOEK IS VERY RESPECTFULLY DEDICATED BY HIS OBLIGED FRIEND, THE AUTHOR. ELLIS'S FORMULARY The first and second editions were issued by the author. The third, fourth, fifth, sixth, seventh, eighth, and ninth editions were revised by the late Samuel Gr. Morton, M. D. The tenth and eleventh editions have been issued under the editorial charge of the late Robert P. Thomas, M. D., and the twelfth under that of Albert H. Smith, M. D. PREFACE TO THE TWELFTH EDITION. In revising the present edition of the Formulary, the progress of medical science in the departments of Materia Medica and Therapeutics has rendered necessary the addition of a considerable amount of new matter ; and in order that the bulk of the work might not be too much increased, the editor has. selected for omission such formulae as seemed of least value, most of them containing remedies long since fallen into disuse, and scarcely obtainable by the class of physicians for whom the work is in- tended. The table of doses has been very carefully cor- rected; the doses of some articles being divided in reference to their therapeutic application, and all calculated for the administration of pure pharma- ceutical preparations of standard strength, and for adult patients. It has been thought best to inclose in brackets the new formulae, that the attention of young prac- titioners may be called to them, as illustrating the practice of recent authorities in therapeutics. In addition to the new formulae, the editor has VI PREFACE TO THE TWELFTH EDITION. added to the work the new classes of Ant emetics and of Disinfectants; besides making insertion under the proper classes of brief references to the inhala- tion of Atomized fluids, the nasal douche of Thudi- ehum, suggestions upon the method of hypodermic injection, the administration of anaesthetics, and some other minor matters, all of which he hopes will add to the value of the work. A new feature of the Formulary will be found in a full index of diseases, with reference to the numbers and principal ingredients of the particular formulae applicable to each. Philadelphia, October, 1868. PREFACE. The elegant and judicious formation of prescrip- tions is one of the difficulties which the young prac- titioner in medicine is obliged to encounter. While a student, he is compelled, from the circumstances under which he is placed, to confine his attention to the leading principles of the science. Consequently, the minor points (and the art of directing medicines is considered one of them) are postponed to that period when he shall have undertaken the practical duties of his profession. To obviate, in some measure, the inconvenience which the graduate at first experiences, the volume now offered the public was undertaken and executed. It contains, in a condensed form, and we think ad- vantageously arranged, many of the most important prescriptions employed in modern practice, and which, though most of them may be already re- corded, are scattered through various medical works. The arrangement framed by Professor Chapman for his Therapeutics, appearing to combine greater advantages than any other, we have taken the liberty of adopting it as the basis of this Formulary. Vlll PREFACE. Each Class has been subdivided into Powders, Pills, and Liquids, without any attempt to preserve the different preparations of the same article together, but only with a view to convenience. A few concise rules will be found prefixed to each Class, and ob- servations have been attached to those prescriptions which possess peculiarities either in their composi- tion or effects. The application of the remedies to diseases has been generally left to the judgment of the practi- tioner, and therapeutical detail as much as possible avoided, as it would have been inconsistent with the nature and design of the work. The object is to furnish models for extempora- neous formulas, the proportions of which may be either increased or diminished, according to the age, sex, constitution, or idiosyncrasy of the patient, all of which are to be taken into consideration when a prescription is directed, as well as the climate and peculiar epidemic which may be prevailing. The prescriptions have been couched in the Latin language, and the names of the several articles will be found regularly terminated. The design was to furnish something like a Medical Grammar to those unacquainted with the dead language ; and even those versed in the classics may occasionally find words used in prescriptions which are new to them. A series of Dietetic Preparations and the principal Poisons have been placed in Book III. The former are written in the English language, and it is hoped PREFACE. IX that they may be found useful in furnishing direc- tions necessary to he given to the nurse. The latter are those Poisons which are usually taken by accident or design, with their appropriate antidotes and some practical observations. Appendix ISTo. I contains some concise remarks on the mode of using remedies on the "Midermic plan" as well as the quantities employed, and the effects produced by several of the most potent remedial agents. 1 The materials for the work have been collected from various sources — the writings of different au- thors, periodical journals, manuscripts, and the con- tributions of our friends. It is hoped, therefore, that the difficulties which have attended its progress will form some apology for the errors which it may possi- bly be found to contain. As a reason for not more frequently attaching the names of authors to the prescriptions, it may be observed that they are a kind of common medical property, which every phy- sician feels himself privileged not only to employ, but modify as may best correspond with his own views. It is, therefore, difficult to say to whom many of them belong : they have been touched and retouched till they have lost their identity. In conclusion, we beg leave to present our ac- knowledgments to some of our friends for the en- 1 Appendix No. II. is a concise and able article on the use of Ether and Chloroform, drawn up by the late Dr. Morton, to which the attention of the reader is directed. X ' PREFACE. couragement they have given to the undertaking. To Dr. Chapman Ave are particularly indebted for the kindness and interest he has manifested in its publication, and offer to him (the only return we can make) our warmest thanks. It is with particular pleasure we embrace this op- portunity of expressing our obligations to our friend Dr. S. G. Morton, whose intimate acquaintance with the subject, and classical knowledge, are only equalled by the kindness and industry he has dis- played in facilitating the work. There are others whose names it would gratify us to mention, but who, we know, will be more pleased by our silence. The countenance they gave us on the present occasion has only increased the debt pre- viously incurred. B. E. CONTENTS PAGE Preface of the Editor . . . . v Preface of the Author vii Introduction xv Table of Drops xvii Table of Abbreviations xix Table of Doses for Children ...... xx Table of the Doses of Medicines xxi Tabular View of the Doses of the Principal Articles of the Materia Medica xxiii BOOK I. OF INTERNAL REMEDIES. Class I. Emetics 33 Powders 34 Solutions and Mixtures ....... 36 II. Antemetics ' 38 Pills and Powders 39 Solutions and Mixtures 40 III. Cathartics 42 Powders 43 Pills . 46 Confections and Electuaries ...... 51 Emulsions and Mixtures 51 Infusions and Decoctions ...... 55 Wines and Tinctures 56 Eneinata . . . . . ... . . 57 Suppositories 59 IV. Diuretics 60 Powders 60 Pills 61 Infusions and Decoctions 63 Solutions and Mixtures 65 V. Antilithics and Lithontriptics 72 Powders and Pills 72 /Solutions and Mixtures 73 Xll CONTENTS. Class page VI. Diaphoretics 77 1. Ordinary Diaphoretics 78 Powders 78 Solutions and Mixtures 80 Infusions 85 2. Alterative Diaphoretics 86 Pills 86 Decoctions 86 Mixtures . . 87 VII. Expectorants 89 Powders, Pills, and Lozenges 89 Syrups 93 Mixtures 96 Inhalation 106 VIII. Emmenagogues 113 Powders and Pills 113 Fluid Preparations 116 IX. Anthelmintics 120 Powders, Pills, and Lozenges 120 Infusions and Decoctions 123 Electuaries and Mixtures 124 Clysters 127 X. Stimulants 128 Powders and Pills 128 Mixtures and Infusions 129 XI. Narcotics 138 Pitts 138 Mixtures, etc. 142 Clysters and Suppositories 149 External Use of Narcotics 151 XII. Antispasmodics 156 Pills, etc. 156 Mixtures, etc. . . . . . . . .157 XIII. Sialagogues . 160 XIV. Tonics 164 1. Anti-intermittents 164 Powders and Pills 164 Decoctions, Solutions, and Mixtures . . . 169 2. Ordinary tonics 173 Powders and Pills 173 Decoctions and Infusions 180 Mixtures and Tinctures 183 XV. Alteratives 192 Powders and Pills 192 Tinctures and Mixtures 196 XVI. Astringents 208 Powders and Pills 208 Mixtures and Infusions . . . . . 212 CONTENTS. Xlll Class page XVII. Absorbents or Antacids 220 Poicders and Pills 220 Mixtures and Solutions 222 BOOK II. OP EXTERNAL APPLICATIONS. XVIII. Caustics or Escharotics 227 Issues and Setons 233 XIX Epispastics 235 XX. Kubefacients 239 XXI. Anomalous External Applications 248 A. Collyria ..'...... 248 Powders 248 Solutions and Mixtures 249 B. Injections ........ 255 a. For the Ear 256 b. For the Nostrils . 258 c. For the Urethra 259 C. Vaginal injections 264 Inoculation and subcutaneous injection of medi- cines 265 D. Gargles and Mouth Washes ..... 267 E. Liniments, Lotions, etc. ....... 273 F. Ointments 285 Powders 298 0. Cataplasms 300 H. Baths .302 1. Fomentations 304 K. Fumigations ........ 305 L. Disinfectants ........ 307 BOOK III. OP DIETETIC PREPARATIONS AND POISONS. Dietetic Preparations and Beverages for the sick . . . .313 Poisons . 327 Appendix I. Enclermic Use of Medicines ..... 339 II. Use of Ether and Chloroform 340 Index . 347 INTRODUCTION Before entering upon the main object of this work, it is necessary to notice a few circumstances which pertain more especially to Pharmaceutic Chemistry, yet appear to be called for in this place ; and, though they are familiar to every educated physician, may be useful to the student who has not yet turned his attention to prescriptions. In the first place, it is requisite to be well ac- quainted with the signs of quantity, or those symbolic characters which are used in writing prescriptions. In the ancient practice of medicine, there were very many of these symbols, not only for the purpose of denoting the quantity of the ingredient, but the in- gredient itself. Most of these, however, have become obsolete; and a few only are retained as indispensable to the convenience of the practitioner. These will be found in the following table, which is adopted in the Pharmacopoeias for the regulation of weights. English name. Latin name. Symbol. Contains. A pound, An ounce, A drachm, A scruple, Libra, Uncia, Drachma, Scrupulus, 3, 5, 9, 12 ounces, 8 drachms, 3 scruples, 20 grains. XVI INTRODUCTION. Iii the manipulation of liquid substances, measures have, in most countries, superseded the use of weights. Particular names and symbols are given to the parts forming a gallon, in order to prevent their being con- founded with those denoting weights ; as in the fol- lowing table : — English name. Latin name. Symbol. Contains. A gallon, A pint, A fluiclounce, A fluidrachm, Congius, Octarius, Fluiduncia, Fluidrachma, C, or Cong., o, ff, f5, 8 pints. 16 fluidounces. 8 fluiclrackms. 60 minims (n\J. The minims used in the table have been adopted in the United States Pharmacopoeia in place of drops; and although we have only partially employed this measure in our prescriptions, yet we can readily per- ceive it to possess some important advantages over the ancient practice. The symbol (n^) is sometimes used by medical writers, though very improperly, to denote both minims and drops. The size of a drop varies according to the greater or less fluidity and gravity of the liquid, and the shape of the vessel from which it is dropped ; but, as a general rule, we cannot do better on these occasions than use a small vial with a thin edge. Dr. Dorsey observes that, whenever great precision is necessary, it is easy to dilute the active medicine, and give it in the form of a mixture. Elias Durand, Prof. Procter, and Edward Parrish, of this city, have made various experiments to ascer- INTRODUCTION. XV 11 tain the number of drops of different liquids equivalent to a fluidrachm; and the results, which are of prac- tical importance, are partly given in the following table : — Acid, acetic (crystallizable) » . DROPS 120 Acid, hydrocyanic (medicinal) • 45 Acid, muriatic .... . 54 Acid, nitric . 84 Acid, sulphuric .... . 90 Acid, sulphuric, aromatic . 120 Alcohol (rectified spirit) . . 138 Alcohol, diluted (proof spirit) . 120 Arsenite of potassa, solution of . 57 Chloroform . 200 -260 Ether, sulphuric .... . 150 The essential oils .... 90 -110 Syrup of acacia .... . 58 Syrup of squill .... . 88 Tincture of assafetida, of foxglove, of g uaiac, of opium • 120 Tincture of chloride of iron . 132- -150 Vinegar, distilled .... . 78 Vinegar of colchicum . . 78 Vinegar of opium (Black Drop) . 78 Vinegar of squills . 78 Water, distilled . 45 Water of ammonia (strong) . . 54 Water of ammonia (weak) . 45 Wine, Teneriffe . 78 Wine, antimonial . . 72 Wine of colchicum . 75 Wine of opium . 2 • 78 XVlll INTRODUCTION. Xow it is evident from the preceding facts, that in giving one hundred and fifty drops of sulphuric ether (and proximately of any ethereal tincture), we give but a fluidrachm ; whereas the same number of drops of medicinal hydrocyanic acid (one of the most poisonous preparations of the Materia Medica),' would be equal to something more than three flui- drachms. The same remark, it will be observed, is applicable to various other preparations, which sug- gests a caution in rapidly increasing the dose of such medicines by drops. Whenever a tablespoonful of any liquid is ordered, it is considered to be equal to half an ounce by mea- sure ; and in the same way a teaspoonful is used for a fluidrachm. These measures are sufficiently accu- rate where no great precision is requisite. The prescriptions contained in this work are given in the Latin language, without other abbreviations than those in common use to denote the quantity of an ingredient. The directions for the administration of medicines are expressed in English. Prescriptions, as usually sent to the apothecaries, are much abbreviated, and the same course may be pursued with regard to those contained in this collec- tion. For the information of students who have not been in the practice of writing prescriptions, a Table of Abbreviations is subjoined. INTEODUCTION. XIX TABLE OF ABBREVIATIONS. Abbreviations. Latin word. English word. aa. Ana, 1 Of each. Ad saturand. Ad saturandum, Until saturated. Ad lib. Ad libitum, At pleasure. Aq. tepid. Aqua tepida, Warm water. Aq. ferv. Aqua fervens, Hot water. C. Congius, A gallon. Chart. Char tula, A small paper. Coch. Cochlear, A spoonful. Coch. mag. Cochlear magnum, A tablespoonful. Coch. parv. Cochlear parvum, A teaspoonful. Colent. Colentur, Let them be strained. Collyr. Colryrium, An eye-water. Contus. Contusus, Bruised or broken. F. vel Ft. Fiat vel fiant, Let there be made. Fol. Folium, vel folia, A leaf, or leaves. Garg. Gargarysma, A gargle. Gr. Granum, vel grana, A grain, or grains. Gtt. Gutta, vel guttse, A drop, or drops. Haust. Haustus, A draught. Infus. Infusum, An infusion. M. Misce, Mix. Mass. Massa, A mass. Mist. Mistura, A mixture. 0. • Octarius, A pint. Pil. Pilula, vel pilulse, A pill, or pills. Pulv. Pulvis, vel pulveres, A powder, or powders. Q.S. Quantum sufficit, A sufficient quantity. R. Recipe, Take. Rad. Radix, A root. S. Signa, Write. Ss. Semis, The half. Tinct. Tinctura, A tincture. The doses throughout this work are applicable to adult age, unless the contrary is specified. For the convenience of young practitioners, the rules furnished by Gaubius and Dr. Young, for 1 This is not properly a Latin word, but the Greek preposition *va. XX INTRODUCTION. ascertaining the proper closes of medicines for child- ren, are given below. Gaiibins takes the dose for an adult as unity, and for other ages, as follows : — One year old . . -^ Seven years old . . -J Two years old . . J Fourteen years old . J Three years old . . J Twenty years old . § Four years old . . \ From 20 to 60 years old 1 Dr. Young says : " For children under twelve years, the doses of most medicines must be dimin- ished in the proportion of the age, to the age in- creased by 12." Thus for a child of two years, 2 : 2 + 12 : : the adult dose, or 1 : to the child's dose, 2 or 7. Or to state it more simply, — — T7 ,= A. Hence, 1 J ' 2+12 7 For one year, 1 + 12 13 " two years, 11 three " four 2 + 12 ' 34-12 5 4 + 12 — 4 6 _i 6 + 12 3 " six etc. etc. At twelve, the dose is one-half that of the adult. An exception should be made in the administration of opiates to very young children, the dose requiring to be diminished in greater proportion than that of the table. In the case of mercurials, on the other hand, the dose is greater, the susceptibility to their impression being less, proportionately, than in adults. TABLE OF THE DOSES OF MEDICINES, ARRANGED IN ALPHABETICAL ORDER. In preparing the following Table, a great object has been to present, at a glance, the minimum and medium doses of each medicine; or, as sometimes happens in respect to the more familiar articles, the ordinary dose, as in many of the infusions and tinc- tures. It is necessary to premise that these prepa- rations are adapted to adult age; nor can any precise rule be laid down which will be applicable to all the periods of life between that period and early infancy. Nothing but the cautious observation and judgment of the physician can possibly supply this deficiency. The best mode of giving active medicines to infants is in solution or suspension, so that the dose may be readily and safely graduated in reference to age, con- stitution and disease. "We would also impress upon every practitioner, the vital importance of knowing the properties and strength of a medicine before prescribing it ; and this caution is especially requisite in directing those pre- parations which, in an overdose, produce distressing and sometimes fatal effects. No prescription of this kind should ever be copied at random, and without XX11 INTRODUCTION. first satisfying one's self, by a little calculation, whether the proportions directed in it are safe and consistent ; and we would farther insist that the use of every poisonous medicine should be commenced in a minimum dose, and gradually increased accord- ing to its effects on the system. It is often neces- sary, also, in these instances, to put the patient on his guard in case any inordinate or unusual symp- toms should arise, with a request that the prescrip- tion, in such contingency, may be taken in less quantity, at longer intervals, or discontinued. This precaution is all-important, for example, in the ad- ministration of alterative doses of the mercurial pre- parations ; for the same quantity that would have little or no effect on one person, might, and often does, produce a violent and deleterious effect on another. This remark is also equally applicable to the whole class of narcotic medicines. In giving the doses of the narcotic extracts, refer- ence is had to the best preparations recognized by pharmaceutists as having a standard strength and purity, as, for example, the well-known extracts of Squire, of London, between whose preparations and those of some other manufacturers there may be a difference of strength, and therefore of dose amount- ing to three or four times the weight. In truth, nothing but habitual circumspection in prescribing medicines, can render this art beneficial to the patient or honorable to the physician. TABULAR YIEW DOSES OF THE PRINCIPAL ARTICLES OF THE MATERIA MEDICA. i 2 0- Absinthium, 9j ad ij. Acetonum, gtt. x ad xxx. Acetum, f 3j ad iv. Acidum Arseniosum, gr. ^ ad Benzoicum, gr. x ad xx. Boracicum, gr. v ad x. Gallicum, gr. iij ad x. Hydrocyanicum Dilutum, gtt. j ad iij. Muriaticura Dilutum, gtt. xx. Nitricum Dilutum, gtt. x ad xx. Nitro-muriaticum, gtt. iij ad x. Phosphoricum Glaciale, gr. j ad ij. Phosphoricum Dilutum, gtt. xv ad xxx. Sulphuricum Dilutum, gtt. x ad xx. Sulphuricum Aromaticum, gtt. x ad xx. Tannicum, gr. ij ad vj. Tartaricum, gr. xx ad 3ss. Aconiti Folium, gr. j ad ij. , Extractum Alcoholicum, gr. I ad i. Folii, Tinctura, gtt. x ad xx. Radicis, Tinctura, gtt. ij ad v. JEther, f 3ss ad j. , Spiritus Compositus, f 5.1- ^Etheris Nitrosi Spiritus, f5ss adj. Allium, 5ss ad j. Allii, Succus, f§ss. Syrupus, f 5j ad ij. Aloe, gr. iij ad x. Aloe et Canella, gr. v Aloes, Tinctura, f^ss. Yinum, f 5j ad fgss. xx. Alumen, expectorant, gr. iij ad x emetic, 3j ad ij. Exsiccatum, gr. v ad x. Ammoniae Acetatis, Liquor, fjss adj. Carbonas, gr. v ad x. ■ Phosphas, gr. x ad xx. Murias, gr. v ad xv. . Spiritus, Aromaticus, gtt. xx ad xxx. Ammoniacum, gr. x ad xx. Ammoniaci, Mistura, fjfss. Angustura, gr. x ad xx. Angusturas, Infusum, f 3ij. Anthemis, 3ss ad j. Anthemidis, Infusum, f 5J ad ij. Antimonium Sulphuratum, gr. j ad v. Antimonii, Oxidum, gr. iij ad v. Oxysulphuretum, gr. ss ad ij. XXIV TABLE OF DOSES. Antimonii et Potassae Tartras, dia- phoretic, gr. T ^ ad £ ; emetic, gr. j ad ij. , Tin urn, gtt. x ad f3j. Antiraonialis, Pulvis, gr. iij ad x. Apoeynurn, gr. x ad xxx. Argenti Nitras, gr. £ ad J. Cyaniduin, gr. ^. Iodidura, gr. J ad j. S 1 ' S' Arnica, gr. v ad xx. Arnicae, Extractum Alcoholicum, gr. ij ad v. , Tinctnra, gtt. xx ad f 3j . Arseniosum Acidum, gr. -^ ad -j^. Arsenici Iodidum, gr. ^ ac ^ s- Arsenici et Hydrargyri Iodidi, Li- quor, gtt. v ad x. Potassae Arsenitis, Liquor, alterative, gtt. iij ad viij j antiperiodic, gtt. v ad xv. Asclepias Tuberosa, gr. xx ad 3j- Assafoetida, gr. iij ad x. Assafcetidae, Mistura, fsss. , Tinctura, f3j. Atropia, gr. jfo ad F V Atropiae Sulphas, gr. g^ ad ^V- Auri Sales, gr. T ' ¥ ad -^j. Balsamum Peruvianum, fjss. Tolutanum, gr. x ad xxx. Tolutanus, Syrupus, fgss. Tolutana, Tinctura, f 3j. Barii Chloridi, Liquor, gtt. v. Bebeerinae Sulphas, gr. iij ad xx. Belladonnas, Folium, gr. j. , Extractum, gr. J ad ^. , Extractum Alcoholi- cum, gr. J. Tinctura, gtt. x ad xx. Benzoinum, gr. v ad x. Benzoini Composita, Tinctura, f 3ss adj. Bismuthi Subcarbonas, gr. iij ad x. . Subnitras, gr. iij ad x. Brominium, gtt. | ad £. Brucia, gr. J. Buchu, gr. xx ad xxx. , Extractum Fluidum, f5ss adj. , Infusum, f^ij. Cahinca, 9j ad 5j- Calamus, 9j ad 5j- Calcis, Liquor, f5ss ad ij. , Syrupus, f3ss ad ij. Calcii Chloridi, Liquor, gtt. xxx ad f 3j. Calx Chlorinata, gr. iij ad vj. Creta Praeparata, gr. x ad xxx. Testa Praeparata, gr. x ad xxx. Camphora, gr. ij ad x. Camphors, Aqua, fgss. Spiritus, gtt. v ad xx. Canella, gr. x ad xxx. Cannabis, Extractum Purificatum, gr. i ad J. , Tinctura, gtt. v ad xx. Cantharis, gr. j ad ij. Cantharidis, Tinctura, gtt. iij ad x. Capsicum, gr. v ad x. Capsici, Tinctura, gtt. v ad xx. Cardamomum, gr. x ad xxx. Cardamomi, Tinctura, f3j. , Tinctura Composita, Carum, gr. xx ad xl. Caryophyllus, gr. v ad x. Caryophylli Oleum, gtt. j ad ij. Cascarilla, gr. xx ad xxx. Castoreum, gr. x ad xx. Castorei Tinctura, gtt. xx ad 1. Catechu, gr. x ad xxx. Tinctura, f 5j ad ij. Cerevisiae Fermentum, f5ss ad ij. Cetrariae, Decoctum, f^ij. Chenopodium, 9j ad ij. Chenopodii, Oleum, gtt. v ad x. Chimaphilae, Decoctum, f .5 i j . Chloroformum, gtt. v ad xxx. Chondri, Decoctum, ad libitum. Cimicifuga, 9j ad 3j- Cimicifugae, Extractum Fluidum, n^xx ad xl. TABLE OF DOSES, XXV Cinchona, gr. x ad xx. Cinchonas, Extractum, gr. x. , Extractum Fluidum, n^ xx ad f5j. , Tinctura, f 5j ad iv. , Tinctura Composita, f 5j ad iv. Flavas, vel Rubra?, De- coctum, fgj ad ij. Flavas, vel Rubra, In- fusum, f Jj ad ij. Cinchonias Sulphas, gr. ij ad x. Cinnamomum, gr. x ad xx. Cinnamorai, Aquas, foss. , Oleum, gtt. j ad ij. , Spiritus, gtt. x ad xxx. , Tinctura, f'3j ad ij. Coccus, gr. j ad x. Colchici Radix, gr. ij ad vj. Semen, gr. ij ad vj. , Tinctura, f 3ss ad j. , Acetum, f 5ss ad j. , Extractum Aceticum, gr. j. Radicis, Vinum, gtt. x ad xx. Radicis, Extractum Flu- idum, n^ij ad v. Seminis, Yinum, fjj. Seminis, Extractum Flu- idum, n\Jj ad vj. Colocynthis, gr. v ad x. Colocynthidis, Extractum Com- positum, gr. iij ad x. Calumba, gr. x ad xx. Calunibas, Infusum, f^ij. , Tinctura, f 5j ad iv. Conii Folium, gr. iij. , Extractum, gr. ij. , Extractum Alcoholicum, gr. ij ad v. , Extractum Fluidum, gtt. v. , Tinctura, gtt. xx ad xxx. Copaiba, f5j. Copaibae, Oleum, gtt. x ad xv. Coptis, gr. x ad xxx. Coriandrum, 9j ad 3j- Cornus Florida, gr. xx ad xxx. Creasotum, gtt. j. Creta Praparata, gr. xv ad 5j- Crocus, gr. x ad xx. Cubeba, 5ss ad iij. Cubebas, Oleoresina, ir^x ad xxx. ., Oleum, gtt. x acl xij. •, Tinctura, f3j- Cuprum Ammoniatum, gr. ^ ad J. Cupri Sulphas, gr. J ad ij. Dippel's Animal Oil, gtt. v ad x. Digitalis, gr. j ad iij. , Extractum Alcoholicum, gr. -J ad j. , Infusum, f 5ij ad iv. Tinctura, gtt, x ad xxx. Digitalin, gr. ¥ V Donovan's Solution, gtt. v ad xx. Dover's Powder, gr. x. Dracontium, gr. x ad xx. Dulcamara, 3ss ad j. Dulcamaras, Decoctum, f|ij. , Extractum, gr. v ad x. , Extractum Fluidum, fjss ad j. Elaterium, gr. J. Elaterin, gr. -^g. Ergota, gr. xx. Ergotas, Yinum, f-Jj ad f^ss. , Extractum Fluidum, f^ss ad j. Ether, fjss ad fjj. Eupatorii, Infusum, f ^ij. Extractum Cannabis, gr. J ad ^. Fel Bovinum, gr. v ad x. Ferri Chloridi, Tinctura, gtt. x ad xxx. Citras, gr. v ad x. et Ammonias Citras, gr. v. et Ammonias Sulphas, gr. v. et Ammonias Tartras, gr. v. et Potassas Tartras, gr. x ad xx. et Quinias Citras, gr. v. Ferrocyanidura, gr. iij ad v. Iodidi, Syrupus, gtt. x ad xl. Lactas, gr. j ad iij. Nitratis, Liquor, gtt. viij ad x. XXVI TABLE OF DOSES, Ferri Phosphas, gr. v ad x. Pyrophosphas, gr. iij ad x. Subcarbonas, gr. x ad 5U- Carbonatis, Pilulse, gr. iij ad v. Sulphas Exsiccata, gr. ij ad v. ■ Valerianas, gr. j. Yinum, f 3ss. Ferrum Ammoniatum, gr. v ad x. Redactum, gr. ij ad v. Filix Mas, 3j ad ij- Fceniculurn, 9j ad 3ss. Foeniculi, Aqua, f^ss. Fowler's Solution, alterative, gtt. iij ad v ; antiperiodic, gtt. v ad xv. Galla, gr. x ad xx. Gambogia, gr. ij ad iij. Gaultheriaa, Oleum, gtt. ij ad v. Gentiaua, gr. x ad xxx. Gentianas, Extractum, gr. v ad x. , Extractum Fluidum, f5ss. , Composita, Tinctura, f5j ad ij. Gillenia, gr. xx ad xxx. Granati Fructiis Cortex, gr. xx ad xxx. Guaiaci Resina, gr. x ad xx. , Tinctura, f 3j- Ammoniata, Tinctura, f 3j. Haeniatoxyli, Extractum, gr. x ad xx. Decoctum, fgj ad ij. Helleborus, gr. v ad xv. Hellebori, Extractum, Alcoholi- cum, gr. v ad x. , Tinctura, gtt. xxx ad f5j. Hoffmann's Anodyne, f3j. Hordei, Decoctum, ad libitum. Humuli, Tinctura, f5ij. Hydrargyri Chloridum Corrosivum, gr. T V ad J. Chloridum Mite, gr. ^ ad j as an alterative, gr. v ad xv as a pur- gative. Hydrargyri Cyanidum, gr. T \ ad J. Iodidum Yiride gr. -J ad ij. Iodidum Rubrum, gr. i T6-* Oxidum Nigrum, gr. J ad iij. Sulphas Flava, gr. \ ad v. Sulphuretum Nigrum, gr. v ad x. Sulphuretum Rubrum, gr. x. Hydrargyrum cum Creta, gr. v ad x. cum Magnesia, gr. v ad x. Hyoscyami Folium, gr. v ad x. , Extractum, gr. ij ad x. , Extractum, Fluidum, gtt. v ad x. , Tinctura, f5ss ad j. Ignatias, Extractum, Alcoholicum, gr. J ad -|. Inula, 9j ad 3j- Iodinium, gr. J ad j. Iodinii, Tinctura, gtt. v ad x. ■, Tinctura, Composita, gtt. x ad xx. , Liquor, Compositns, gtt. v ad x. Ipecacuanha, as diaphoretic, gr. \ ad j ; emetic, gr. x ad xxx. Ipecacuanhas, Syrupus, f 5j ad ij. , Extractum, Fluidum, gtt. x ad xxx. , Vinum, f5j. , Pulvis, Compositus, gr. x. Jalapa, gr. x ad xx. Jalapae, Extractum, gr. v ad x. -, Resin a, gr. j ad iij. Tinctura, f5j acl ij. Juglandis, Extractum, gr. xx. Juniperi, Baccae, 3j ad ij. , Oleum, gtt. v ad xv. TABLE OF DOSES XXVll Jumped, Spiritus, Compositus, f 5j ad iv. Kainela, 3j ad ij- Kino, gr. x ad xx. , Tinctura, f5j ad ij. Kousso, Flores, oSS. Krameria, gr. xx ad xxx. Krameria?, Extractum, gr. x ad xx. , Syrupus, f 5j ad iv. , Tinctura, f5j. Lactucarium, gr. iij ad x. Lactucarii, Syrupus, f3j. Lappa, 3j. Lauro-Cerasi, Aqua, f 3ss ad j. Lavandula, Oleum, gtt. ij ad v. , Spiritus, Compositus, Liriodendron, 5ss ad ij. Lobelia, gr. v ad x. Lobelia?, Tinctura, gtt. v ad xx. Lugol's Solution, gtt. v ad x. Lupulina, gr. v ad x. Lupulina?, Tinctura, fjj. , Extractum, Fluidum, gtt. v ad x. , Oleoresina, gr. j ad iij. Magnesia, 3ss ad j. Magnesia? Carbonas, 3ss ad j. Citratis, Liquor, f Jivad xij. Sulphas, 5ij ad sj. Magnolia, 5ss ad j. Manganesii Oxidum, gr. iij ad x. Iodidi, Liquor, gtt. x ad xx. Sulphas, 9j ad 5U- Manna, £ss ad j. Mannite, Jj. Matico, 5ss ad ij. Matricaria, 5ss ad j. Mentha? Piperita?, Oleum, gtt. j ad f Spiritus, gtt. x ad xxx. , Aqua, f 5ss. Mentha? Viridis, Aqua, fjss. Mentha? Yiridis, Spiritus, gtt. x ad xx. Mezerei, Decoctum, f ^ij. Mistura Creta?, f^ss ad j. Monarda?, Oleum, gtt. j ad iij. Morphia? Acetas, gr. jr ad J. Murias, gr. ^ ad J. Sulphas, gr. J ad J, Sulphatis, Liquor, fjj ad fgss. Moschus, gr. x. Mucuna?, Electuarium, 5j ad ^ss. Myrrha, gr. x ad xx. Myrrha?, Tinctura, fjss adj. Naphthalina, gr. ij ad xv. Nucis Yomica?, Extractum, Alco- holicum, gr. \ ad J. Tinctura, gtt. v ad x. Nux Yomica, gr. iij ad v. Oleum Amygdala? Amara?, gtt. \. Ani si, gtt. ij ad v. Cajuputi, gtt. ij ad v. Erigerontis Canadensis, gtt. v ad x. Limonis, gtt. ij ad iv. Morrhua?, fgj ad f^ss. Oliva?, f gj. Pimenta?, gtt. ij ad v. Ricini, f gj. Rosmarini, gtt. ij ad iij. Ruta?, gtt. ij ad iij. Sabina?, gtt. ij ad iij. Sassafras, gtt. iv ad vj. Succini Rectificatum, gtt. v ad x. Terebinthina?, stimulant, gtt. v ad xx ; anthelmintic, f 5j ad ij. — — Tiglii, gtt. \ ad ij. Opium, gr. j. Opii, Acetum, gtt. x. , Confectio, gr. x ad xx. , Extractum, gr. ss. , Tinctura, gtt. xx ad xxv. , Tinctura, Acetata, gtt. xx. Tinctura, Camphorata, f 5j ad ij. XXV111 TABLE OF DOSES Opii, Tinctura, Deodorata, gtt. xx ad xxx. , Yinum, gtt. xx ad xxv. Pareira, 3ss ad j. Petroleum, 5ss ad j. Phloridzin, gr. x ad xij. Piperis, Oleoresina, gtt. j ad iij. Pix Liquida, 5ss ad j. Plumbi Acetas, gr. j ad iij Iodidum, gr. \ ad iij. Nitras, gr. \ ad j-. Podophylli, Extractum, gr. v ad xv. , Resina (Podophyllin), gr. T \ ad J. Potassas, Liquor, gtt. x ad xx. Arsenitis, Liquor, gtt. v; alterative, gtt. iij ad viij ; antiperiodic, gtt. v ad xv. Acetas, gr. x ad xx. Bitartras, 5j ad ij. Carbonas Pura, gr. x. Bicarbonas, gr. x ad 5ss. Chloras, gr. x ad xx. Citras, gr. xx ad xxv. Citratis, Liquor, fjss. Nitras, gr. x ad xv. Sulphas, 5ss ad j. Tartras, 3j ad §ss. Potassii Bromidum, gr. iij ad x. Cyanidum, gr. J. Ferrocyanidum, gr. x ad xv. Iodidum, gr. iij ad x. Sulphuretum, gr. ij ad vj. Primus Yirginiana, 5ss adj. Pruni Yirginianas, Iufusum, f*ij. , Extractum, Fluidum, f5ss ad j. , Syrupus, f^ss. Pulvis Aromaticus, gr. x ad xx. Doveri, gr. x. Quassias, Extractum, gr. ij ad v. ■ , Tinctura, fjj ad ij. Quercus Alba, et Q. Tinctoria, gr. xx ad 5j. Quiniae Sulphas, gr. j ad x. Yalerianas, gr. j ad v. et Ferri Citras, gr. iij ad v. Rhamni Syrupus, fjfss. Rheum, 9j ad 5ss. Rhei, Fluidum Extractum, f£ss. , Extractum Alcoholicum, gr. v ad x. , Syrupus, Aromaticus, fjj ad iv. , Tinctura, f §ss. Yinum, f3ij. Rubia, 9j ad 3ss. Rubus Yillosus, et R. Canadensis, 9j ad 5ss. Sabbatia, 3ss ad j. Sabina, gr. v ad x. Sabinas Oleum, gtt. ij ad iij. Salicin, gr. ij ad x. Sanguinarise, Tinctura, f3ss ad j. , Acetum, gtt. xx ad xxx. Sanguinarinse Sulphas, gr. ^ ad i* Santonin, gr. j ad iij. Sarsaparillse, Extractum, gr. x ad xx. , Extractum, Fluidum, f5j. , Decoctnm, Composi- tum, fgj ad ij.^ , Syrupus, Compositus, fsss. Scammonium, gr. v ad xv. Scammonii, Resjna, gr. ij ad vj. Scilla, gr. j ad ij. Scillae, Acetum, f^ss ad j. -, Syrupus, fgj. , Syrupus, Compositus, f5ss adj. , Tinctura, gtt. x ad xl. Senega, gr. x ad*xx. Senegas, Syrupus, f5j ad ij. , Extractum, Alcoholicum, gr. j ad iij. Senna, 5ss .ad ij. Sennas, Confectio, 3j ad ij. TABLE OF DOSES. XXIX Sennae, Extraction, Fluidum, f 5j ad f|jss. Serpentaria, gr. x ad xxx. Serpentariaa, Tinctnra, f 3j- , Extractum, Fluidum, gtt. x ad xxx. Simaruba, 9j ad 3j- Sinapis (as an emetic), 59- Sodae Acetas, 9j ad 3j- Boras, 9j ad ij. Carbonas, gr. v ad x. Carbonas Exsiccata, gr. ij ad x. Bicarbonas, gr. x ad xx. Phosphas, ^ss ad j. Sulphas, |ss. et Potassae Tartras, 3\j ad 5ss. Sodii Chloridum, gr. x ad 3y- Spigelia, gr. x ad 5j. Spigelian, Extractum, Fluidum, gtt. xx ad f 3j. et Sennas, Extractum Flu- idum, f'5j ad f £ss. Spiritus ^Etheris Nitrosi, f 3ss ad j. Spiritus JEtheris Compositus, f 3ss adj. Spiritus Pyroxilicus, gtt. x ad xl. Stanni Pulvis, §ss. Stramonii Folium, gr. j ad ij. , Extractum, gr. j. , Extractum Alcoholi- cum, gr. J ad j. , Tinctura, gtt. xx ad xxx. Strychnia et ejus sales, gr. ^V ad i Styrax, gr. x ad xx. Sulphur, 9j ad 5ij- Sulphuris Iodidum, gr. I ad j. Tabacum, gr. j ad v. Tabaci, Vinum, gtt. x ad xx. Taraxaci, Extractum, 9j ad 5j- , Extractum, Fluidum, f3J. Terebinthina, 9j ad ij. Testa Praeparata, gr. x ad 1. Ulmi, Infusum, ad libitum. Uva Ursi, 3 SS ad j. Uva3 Ursi, Extractum Fluidum, gtt. x ad f 3j- Valeriana, 3ss ad j. Valerianae, Extractum, Fluidum, f 5ss ad j. , Extractum, Alcoholi- cum, gr. iij ad x. , Oleum, gtt. v. , Tinctura, f5j ad ij. — , Tinctura, Ammoniata, f3j. Veratrum Album, gr. j ad iij. Viride, gr. j ad iij. Veratri Viridis, Extractum, Flu- idum, gtt. ij ad v. , Tinctura, gtt. v ad viij. Veratria, gr. T x ¥ ad J. Zinci Acetas, gr. j ad ij. Chloridum, gr. J ad ij. Cyanidum, gr. T ^ ad \. - Oxidum, gr. ij ad v. - Sulphas, gr. j ad x. Valerianas, gr. \ ad ij. Zingiber, gr. x ad xx. Zingiberis, Tinctura, f3j. , Extractum, Fluidum, gtt. x ad xx. BOOK I. OF INTEENAL BEMEDIES CLASS I EMETICS. Emetics are medicines which excite vomiting, independ- ently of any effect arising from the mere quantity of matter introduced into the stomach. In the administration of Emetics a few simple rules are worthy of attention. Whatever may be the apparant neces- sity for emptying the stomach, we must take into considera- tion all the circumstances of the case, and more particularly if there be much arterial excitement with determination to the head ; for where these symptoms are present, bloodletting should be sometimes premised. When it is required, as in cases of poisoning, a full dose of the emetic substance is to be administered ; but in the gene- rality of instances, it is better to give it in divided doses, fre- quently repeated, until the desired effect is produced. In cases of torpor or congestion, it is sometimes requisite to arouse the system by retching or vomiting, which may be done by administering the emetic with only a small quantity of fluid; but when the object is to empty the stomach and duodenum merely, free draughts of tepid water or weak chamo- mile tea ought to be given as soon as nausea takes place. When poisons have been taken, our object is to evacuate the stomach as speedily as possible, and for this purpose we select an emetic which is prompt in its action. But where the excitability of the stomach is greatly diminished by a Narcotic, it is necessary to assist the emetic by the addition of some excitant. When such an effect is caused by opium, the system may be generally rendered susceptible by the use of vinegar, mustard, or ammonia. In these cases, however, the stomach-tube is our best resource. The evacuation of the stomach may be greatly facilitated by tickling the fauces with a feather, or introducing the point 3 34 : EMETICS. of the finger as far back as possible and titillating the parts. If this fails, a resort to another article of the same class will often accomplish the object. There are a few cases in which emetics are obviously in- admissible, as in apoplexy, or where there is great determina- tion of blood to the head, depending iipon constitutional causes, pregnancy, hernia, prolapsus uteri, active hemorrhage from the lungs and uterus, acute gastritis, etc. If emetic medicines are ever allowable in these diseases, it is for the most part in nauseating doses only. By the frequent use of emetics the stomach acquires an in- creased susceptibility to their action ; hence persons of deli- cate habits should use them cautiously. Powders, etc. 1. Powder of Ipecacuanha. R, Pulveris Ipecacuanhas 9ij. Divide in pulveres ij. Signa. — One powder to be taken in a little molasses, or sugar and water, and to be followed by a draught of tepid water. If one powder does not produce the desired effect, the second is to be taken in like manner. 2. Lozenges of Emetia. &. Emetias Impuras gr. xxxij ; Sacchari 5ij ; Mucilaginis Acacias q. s. ut flat massa, in trochiscos sin- gulos grana xviij pendentes, dividenda. Each lozenge will contain about one-half of a grain of com- mercial emetia, sufficient to vomit a child, or to produce nausea in an adult. Magendie. 3. Poicder of Ipecacuanha with Tartarized Antimony. B. Pulveris Ipecacuanhas 3ss ; Antimonii et Potassas Tartratis gr. j. Misce, et divide in pulveres ij. Let one powder be taken in water, and if vomiting does not ensue in fifteen minutes, give the second in a similar manner. Tartar emetic increases the efficacy of ipecacuanha, pro- ducing a more prompt and certain effect than the latter drug. This combination is an eligible one in most cases where emetics are indicated. When tartar emetic is given alone, it is generally in solution, a formula for which will be found below. {See Formula 10.) EMETICS. 35 4. Powder of Alum. R. Aluminis Ij. Fiat pnlvis. The dose is a teaspoonful, mixed with honey, syrup, or mo- lasses, to be repeated every fifteen minutes until free emesis is produced. C. D. Meigs. 5. Powder of Mustard. R. Pulveris Sin apis Nigras ,?j. Signa. — Take a teaspoonful in a teacupful of tepid water every ten minutes. This is a very prompt and safe emetic. In cases of narcotic poisoning it is necessary to resort to the most prompt and certain means of evacuating the stomach. Ipecacuanha was formerly thought to be a specific for poison- ing by opium, but experience has shown that mustard, salt, alum, turpeth mineral, and the sulphates of zinc and copper are more reliable. [6. Powder of Ipecacuanha and Sulphate of Zinc .] R. Pulveris Ipecacuanhas, Zinci Sulphatis, aa 9ij. Misce, et div. in chart, iv. Signa. — Take one every fifteen minutes until vomiting. 7. Powder of Ipecacuanha and Calomel. R. Pulveris Ipecacuanhas gr. viij ; Hydrargyri Chloridi Mitis gr. v. Misce. This powder generally proves both emetic and purgative. It is often indicated in the commencement of the eruptive and other diseases of childhood in doses of 2 or 3 grains. 8. Powder of Ipecacuanha and Rhubarb. R. Pulveris Ipecacuanhas, Pulveris Ehei, aa 3j. Misce. Signa. — To be taken in syrup. More or less purging will generally follow the emetic ope- ration of this dose. It is used in congestive and other fevers. 36 EMETICS, Solutions and Mixtures. 9. Wine of Ipecacuanha and Tartarized Antimony. R. Vini Ipecacuanhas f£j ; Antimonii et Potassas Tartratis gr. j. Fiat solutio. Signa. — A teaspoonful to be taken every ten or fifteen minutes, until vomiting is induced, which may be assisted with tepid drinks. 10. Mixture of Tartrate of Antimony. R. Antimonii et Potassas Tartratis gr. ij ; Sacchari 3j ; Aquas destillatas f lij. Misce, et fiat solutio. Signa. — A tablespoonful to be given every ten or fifteen minutes, until it vomits freely. 11. Mixture of Sulphate of Zinc and Alum. R. Zinci Sulphatis 5jss ; Aluminis 3ss; Aquas ferventis Oss, Misce, et cola. Signa. — A tablespoonful for adults, and a teaspoonful for a child of six months old (and so on in proportion to the strength and age of the patient), every morning upon an empty stomach. This is the celebrated solutio vitriolica of Dr. Mosely, who principally employed it in dysentery and phthisis pulmonalis. 12. Mixture of Emetia. R. Emetias impuras gr. iv; Aquas destillatas f Jij ; Syrupi f 3ss. Fiat solutio. Signa. — Give a dessert- spoonful every half hour. Emetia is destitute of the peculiar odor and nauseous taste of ipecacuanha, and may, therefore, be preferable in some cases. It will be observed that we have introduced the impure or commercial emetia, which is much less energetic than the perfectly white alkaloid. The best antidote for an overdose is a strong infusion of nutgalls. Mag-endie. EMETICS. 37 13. Mixture of Ipecacuanha, Tartar Emetic, and Squill R. Pulveris Ipecacuanhas 3ss ; Antimonii et Potassae Tartratis gr. j ; Tincturas Scillas f 5J ; Aquas destillatas f 3vij. Fiat mistura. Signa. — Pour tablespoonfuls at first; afterwards two table- spoonfuls every ten minutes until vomiting is induced. This mixture is recommended in dropsies previously to giving digitalis. 14. Mixture of Syrup and Wine of Ipecacuanha. R. Syrupi Ipecacuanhas flj ; Yini Ipecacuanhas f3ij. Signa. — Give a teaspoonful to a child three years old, every fifteen minutes until it proves emetic. The syrup of ipecacuanha, by itself, is too mild to act as an emetic, being rather designed as an expectorant. But in combination with the wine it provokes free emesis. CLASS II. AST, EMETICS. Under this head may be embraced all remedies having a tendency to diminish irritability of the stomach, and thereby prevent vomiting and nausea. . Inasmuch as nausea and vo- miting are only symptoms, and not in themselves a disease, attention must be given to removing the cause, if it is ascer- tainable, at the same time that palliatives are administered to remove the symptom. Practitioners will bear in mind the sympathetic disturb- ances of the stomach resulting from cerebral, hepatic, renal, and intestinal diseases, and investigate the condition of those organs as possible cause of the nausea. If an overloaded stomach or the presence of undigested or indigestible food is a probable cause, the effort of nature to get rid of it should be aided by a gentle emetic, as ipecacuanha in dose of 20 grains, powdered mustard in teaspoonful dose, or common salt in the same dose in a tumblerful of tepid water. The simple means to be resorted to to check nausea are as follows: — ' Small pieces of ice, swallowed without being previously melted. A tablespoonful of lime-water, or a teaspoonful of the syrup of lime in two tablespoonfuls of iced milk, every ten minutes. A teaspoonful of iced brandy, every ten or fifteen minutes. An infusion of camphor (made with boiling water), given cold, in teaspoonful doses frequently repeated. Inhaling the fumes of laudanum heated to a rapid evapora- tion, or the vapor of spirits of camphor, or of chloroform, carefully used. External applications may be made with advantage, ano- dyne or rubefacient, such as hot cloths, hot fomentations, ANTEMETICS. 39 mustard cataplasms, and spice plasters. For the latter appli- cation an exceedingly convenient method, especially for tra- vellers, is furnished in the beautiful preparation of portable sinapisms and spice plasters introduced by B. J. Crew, phar- maceutist, of this city. The application of pounded ice to the spine, along the cer- vical and dorsal regions, either in narrow bladders or folded in a napkin, or in the bags of Chapman, will often be useful. In obstinate vomiting, suppositories of powdered opium, containing one grain each, or more if needed, are often very efficient. In the nausea and vomiting sometimes attending the admin- istration of opium internally, the editor has found a strong decoction of Java or Laguayra coffee, given in tablespoonful doses, pure, to give immediate relief. Under the head of tonics will be found many remedies, which, under certain circumstances, will prove antemetic by stimulating the depressed gastric function and removing irri- tability of the stomach. Powders and Pills. [15. Pills of Calomel and Bismuth^ R. Hydrargyri Chloridi Mitis gr. iij ; Bismuthi Subnitratis 3ss; Syrupi q. s. ut fiat massa, in pilulas xij dividenda. Signa. — One pill every two hours. In nausea from gastric irritability, or hepatic derangement. [16. Powder of Calomel and Morphia.'] R. Hydrargyri Chloridi Mitis gr. iij; Morphise Sulphatis gr. j ; Pulveris Sacchari gr. xij ; Misce, et divide in chartulas xij. Signa. — One powder placed upon the tongue every two hours. In gastric irritation, chronic gastritis. [17. Pills of Strychnia and Bismuth^] R. Strychnia? gr. j ; Bismuthi Subnitratis 9iv; Syrupi q. s. Misce, et divide in pilulas xx. Signa. — Take a pill before each meal. In nausea from chronic gastric depression, with pyrosis. 40 ANTEMETIOS. [18. Pills of Oxalate of Cerium.'] R. Cerii Oxalatis gr. xv; Extracti Gentianae gr. v; Misce, et divide in pi]ulas x. Signa. — One pill an hour after each meal. Eecommended by Sir J. Y. Simpson in nausea of pregnancy. [19. Pills of Cerium, Nux Vomica, andiron.] R. Cerii Oxalatis gr. xxiv; Extracti Nucis Vomicae gr. xij ; Ferri redacti gr. xxiv ; Syrupi q. s. Misce, et divide in pilulas xxiv. Signa. — One pill at each meal. In the nausea of pregnancy, with general atony. Solutions and Mixtures. [20. Brandy and Chloroform Mixture.'] R. Chloroformi "Ixv ; Spiritus Yini Gallici fljss. Misce. Signa. — A teaspoonful every half hour, in water. In nausea from nervous depression. [21. Prussic Acid and Morphia^] R. Acidi Hydrocyanici diluti gtt. xxiv; Morphias Sulphatis gr. j ; Elixir Curacoae fljss. Misce. Signa. — A teaspoonful every two hours, in a little pounded ice. In the nausea of cardiac irregularity. [22. Sulphuric Acid and Morphia Mixture^] R. Morphias Sulphatis gr. j ; Acidi Sulphurici Aromatici gtt. lx. Elixir Curacoae (vel Syrupi Aurantii) fojss. Misce. Signa. — A teaspoonful every two hours, in cold water. In nausea from gastric depression, or intestinal irritation. ANTEMETICS. 41 [23. Mixture of Chloroform and Soda.'] R. Chloroformi "ix; Alcoholis puri f5ss; Sodae Bicarbonatis 3ij >' Aquae Menthae Piperitae fjijss. Mi see. Signa. — A tablespoonful every half hour. In nausea attending bowel complaints ; also, in tbe nausea of pregnancy with acidity of stomach. [24. Mixture of Pyroxylic Spirit.] R. Spiritas Pyroxylici Rectificati f*5j ; Tincturae Cardamomi Compositae fjjss. Misce. Signa. — A teaspoonful every four hours. For the nausea of pregnancy. H. E. Eastlake. [25. Creasote and Bismuth Mixture."] R. Creasoti gtt. xij ; Bismuthi Subnitratis 3j ; Pulveris Tragacanthae gr. xxx ; Syrupi Aurantii f^ij ; Aquae fjiv. Misce. Signa. — A tablespoonful every hour or two. In nausea from indigestion. CLASS III. OATHAETIOS. As a general rule it maybe observed of cathartics that they are capable of fulfilling three different indications : 1. Simply to evacuate the bowels ; 2. To excite an increased discharge from the mucous coat of the intestines ; and 3. To stimulate the neighboring viscera, and cause them to secrete a greater quantity of their peculiar fluids. It seldom or perhaps never happens that the same article will produce these three different effects; and in order to accomplish them, we must combine different substances in one formula. There are some, as magnesia, that produce their effect by absorbing the acid generated in the alimentary canal, and thus becoming converted into a purgative salt. There are others, as aloes, that expend their principal force upon the rectum and large intestines, aud for this reason are very advantage- ously employed in diseases of the lower bowels, and of the uterus and its appendages. These remedies should always be given on an empty sto- mach. If administered immediately after a full meal, they arrest the digestive process, are liable to produce nausea, if not vomiting, and do not open the bowels with the same cer- tainty or effect. When simple costiveness is to be removed, the evening may be selected for the exhibition of a cathartic. If this should not prove sufficient, we can repeat the dose in the morning and at regular intervals through the day until the effect is produced. " The principle," says Dr. Paris, "which should govern our conduct in the administration of purgatives, may be briefly stated : The excitement is to he re- peated till the requisite action is induced, yet no single excitement being such as may prove an irritant to the organ." But in the treatment of many diseases it is preferable to purge through the day, in order that the sleep of the patient may not be disturbed at night. CATHARTICS. 43 The operation of these remedies may be very much accele- rated by the free exhibition of diluent drinks, such as gruel, barley-water, etc. etc. By combination we are enabled to modify and control the action of many remedies, and some of the most drastic purga- tives may be made to operate mildly and certainly by uniting small quantities of several of them in the same dose. The addition of an emetic substance, such as tartar emetic, or ipecacuanha, in small quantities, gives activity to the com- bination, while it modifies the harshness of the drastic purga- tives. Finally, the operation of a cathartic may often be promoted by judicious venesection; and if spasm of the intestines be present, opium may be advantageously joined with the purga- tive. Powders. 26. Powder of Calomel and Jalap. R. Hydrargyri Chloridi Mitis gr. v ; Pulveris Jalapse gr. x. Misce. Signa. — To be given in molasses or syrup. 27. Powder of Calomel and Rhubarb. R. Hydrargyri Chloridi Mitis, Pulveris Ehei, aa gr. v ; Olei Cinnamomi gtt. j. Misce. Signa. — To be given in molasses. 28. Powder of Calomel and Soda. R. Hydrargyri Chloridi Mitis gr. viij ; Sodge Bicarbonatis gr. xij. Misce. Signa. — To be given in molasses. This combination forms a safe and mild purgative. Nausea seldom follows its administration. 29. Powder of Calomel, Jalap, and Rhubarb. R. Hydrargyri Chloridi Mitis, Pulveris Jalapse, Pulveris Ehei, aa gr. v ; Olei Cinnamomi gtt. j. Misce. Signa. — To be given in syrup or molasses. 44 CATHARTICS. 30. Powder of Rhubarb and Magnesia. R. Pulveris Khei 9j; Magnesias 9ss ; Olei Cinnamomi gtt. j. Misce. Signa. — To be given in syrup or molasses. 31. Calcined Magnesia. R. Magnesias 3j- R. Magnesias (Henry) 3j. R. Magnesias (Husband) 3j. R. Magnesias (Ellis) 3j. Magnesia is an antacid, and laxative, much used in the dis- eases of women and children. The lightness and consequent bulk of the officinal powder, constitute serious objections to its use. To obviate these, Henry, of England, and Thomas J. Husband, and Charles Ellis & Co., of this city, have seve- rally prepared a heavy magnesia as a substitute. Henry's magnesia has long been favorably known; Husband's and Ellis's are entitled to equal consideration with the imported article, since the experiments of Prof. Procter have shown that, for forming liquid mixtures, and for rapidity of antacid action, they are equal if not preferable to it. Dose of either, from thirty grains to a drachm, in milk or water. The operation of magnesia, when it meets with no acid in the bowels, is promoted by giving the patient lemonade. 32. Powder of Jalap and Cream of Tartar. R. Pulveris Jalapas £j ; Potassas Bitartratis 3yj. Misce, et divide in pulveres yj. Signa. — Give one powder every three hours in molasses. This powder is a hydragogue cathartic. " It constitutes one of the best medicines which I have ever tried, as well in dropsical as in all other cases, where long-continued purging is demanded." N. Chapman. 33. Compound Powder of Jalap and Gamboge. R. Pulveris Jalapas Compositi 3iij ; Pulveris Gambogias gr. yj. Misce, et divide in pulveres vj. Signa. — Give one powder every two hours in molasses or syrup. CATHAKTICS. 45 The compound powder of jalap has long been celebrated in dropsical affections ; but it also forms a very convenient purge in many inflammatory cases. In order to increase its certainty and activity, we may conveniently add gamboge, as in the above formula. 34. Powder of Sulphur and Cream of Tartar. R. Sulphuris loti *ss; Potassse Bitartratis Ij. Misce. Signa. — Mix in a sufficient quantity of molasses, and give a teaspoonful three or four times a day to children. Used in various diseases of the skin. It should be always recollected that sulphur promotes in- sensible perspiration in a very marked degree, and hence renders the patient more liable to be affected by vicissitudes of climate. 35. Powder of Sulphur and Calcined Magnesia, R. Sulphuris praecipitati, Magnesise, aa ^ss. Misce. Signa. — A teaspoonful to be taken three or four times a day. This preparation is better adapted to delicate stomachs than the former. Either of them forms a good aperient during an alterative course of medicine. 1ST. Chapman. 36. Seidlitz Powders. R. Potassse et Sodse Tartratis 3ij; Sodse Bicarbonatis 9ij. Piat pulvis. Signa. — To be dissolved in a wineglassful of cold water. R. Acidi Tartarici pulverisati gr. xxxv. Signa. — Dissolve in a wineglassful of water and mix the two solutions. "To be taken while in a state of effervescence. This is a very popular medicine, and justly so, as it is a gentle aperient, and may be taken by persons whose stomachs would reject any of the ordinary saline preparations. 46 CATHARTICS. 37. Stevens's Saline Powders, B. Sodas Bicarbonatis 3ss ; Sodii Chloridi 3j ; Potassas Cliloratis gr. vij. Misce. This powder was administered by Dr. Stevens in half a tumblerful of tepid water, or a little thin beef tea, in cholera, and repeated every half hour until the patient recovered from the collapse. Pills. 38. Griffitts's Cathartic Pills. B. Pulveris Jalapas, Pulveris Ehei, Saponis, aa Jss; Hydrargyri Chloridi Mitis gr. xxv; Antimonii et Potassas Tartratis gr. jss ; Aquas destillatas, quantum sunicit ut flat massa. Divide in pilulas xxv. Signa. — Two of these pills may be taken at once, and repeated in two hours if not sufficient. This combination of purgatives with the tartrate of anti- mony forms an excellent antibilious remedy ; and, in cases of fever, prepares the alimentary canal for the reception of other remedies. S. P. G-riffitts. 39. Pills of Blue Mass, Jalap, and Aloes. B. Pilulas Hydrargyri, Pulveris Jalapas, Pulveris Aloes Socotrinas, aa gr. xv; Syrupi, q. s. ut flat massa. Divide in pilulas xij. Signa. — Three may be taken at night, and the same dose be repeated in the morning, if the first is ineffectual. 40. Pills of Blue Mass, Rhubarb, and Soda. E. Pilulas Hydrargyri gr. ix; Pulveris Ehei, Sodas Bicarbonatis, aa gr. xij ; Syrupi Ehei Aromatici q. s. ut flat massa, in pilulas xij dividenda. Signa. — One pill to be taken twice or three times a day, as an alterative, in derangement of the liver. Jos. Hartshorne. CATHARTICS. 47 41. Pills of Calomel and Colocynth. R. Extract! Colocjnxthidis Compositi 9ij ; Hydrargyri Chloridi Mitis 9j. Misce, et divide in piliilas xx. Two or three of these pills will generally act as a cathartic. 42. Pills of Colocynth and Podophyllin. R. Extracti Colocynthidis Compositi 3ss; Kesinse Podophylli gr. iij. Misce, et divide in pilulas xij. Signa. — One or two pills at bedtime. This is an excellent substitute for the officinal compound cathartic pill. One pill acts usually as a laxative, and three pills produce free purgation. E. P. Thomas. 43. Pills of Aloin and Podophyllin. R. Aloin gr. xxiv; Kesinse Podophylli gr. xij ; Oleoresinae Zingiberis "liv; Fiat massa, et divide in pilulas xxiv. Signa. — Dose, one pill as a laxative, two or three pills as a purgative. " The experience of numerous practitioners here and in Europe confirms the utility of aloin as a mild though pretty certain cathartic in doses of two to three grains." • E. Parrish. 44. Anti- Gout Pill. R. Extracti Colchici Acetici, Extracti Colocynthidis Compositi, aa gr. x ; Morphise Acetatis gr. ijss. Fiat massa, in pilulas x dividenda. This is a useful anti-gout pill, adapted to mitigate an actual paroxysm. One pill should be given every two hours, until the bowels and kidneys are acted on. Eobert Dick. 45. Becqu&reVs Anti- Gout Pill. R. Quinise Sulphatis 3ij ; Extracti Digitalis Alcoholici gr. xv; Extracti Colchici Acetici 9ij. Fiat massa, et divide in pilulas 1. Signa. — Take one pill every three hours. 48 CATHAETICS. These pills are highly recommended by M. Trousseau, of Paris, in the treatment of gout. 46. Pills of Extract of Butternut and Jalap. R. Extracti Juglandis 3ss ; Pulveris Jalapge 9j ; Saponis gr. x. Misce, et riant pilulae xv. Signa. — Three of these may be taken for a dose, and if they do not operate, two more may be safely administered. The extract of butternut, either alone or in combination, is highly recommended as a cathartic in fevers, dysentery, etc., from its tendency to act on the liver. 47. FothergilVs Pills. R. Extracti Colocynthidis Compositi 3jss ; Antimonii Oxidi Jss. Misce, et divide in pilulas xxx. One of these pills will generally produce a free evacuation ; but two or more may be taken when required. During the last century, the antimonial preparations were held in high repute by the London physicians, and this com- bination of an antimonial with active cathartics is still re- garded with favor. [48. Lartigue's Gout Pill.] R. Extracti Colchici Acetici gr. viij ; Extracti Digitalis gr. iv ; Colocynthidis Compositi 9iv. Misce, et divide in pilulas xx. Signa. — One pill at bedtime. In gout or chronic rheumatism. 49. MitchelVs Aperient Pills. R, Pulveris Ehei 9iv: Pulveris Aloes Socotrinse Bij ; Hydrargyri Chloridi Mitis gr. iv ; Antimonii et Potassae Tartratris gr. ij. Fiat pulvis, et adde — Saponis, in pulverem contriti 9ij ; Aquae q. s. ut fiat massa. Divide in pilulas xl. Signa. — Take one pill every night as a laxative, or three pills as a purgative. J. K. Mitchell, CATHAKTICS. 49 50. Pills of Elateriurn. R. Elaterii gr. ij ; Extracti Grentianse gr. xiv. Misce, et divide in pilulas xvj. Signa. — Give one pill every three hours, until free purging takes place. Elaterin, the active principle of this drug, can now be pro- cured in a, state of purity; and as it is more certain in its effects, a formula- is subjoined under the head of purgative wines and tinctures. 51. Pills of Croton Oil. R. Olei Tiglii gtt. ij ; Micse Panis q. s. ut fiant pilulas iv. Signa. — One every hour until they operate. This powerful remedy has lately been restored to the Ma- teria Medica. One drop is a full dose, and frequently less will answer every purpose. The following is a more certain and less drastic mode of exhibiting the oil. 52. Pills of Croton Oil and Qolocynth. R. Olei Tiglii gtt. ij; Extracti Colocynthidis Compositi gr. x. Misce, et divide in pilulas iv. Signa. — Give one pill every two hours, until a purgative effect is produced. 53. Chapman's Peristaltic Persuaders. R. Pulveris Ehei 3j; Pulveris Ipecacuanhas gr. x; Olei Cari gtt. x; Pulveris Acacias q. s. ut fiat massa. Divide in pilulas xx. Signa. — Take two pills at bedtime, in obstinate constipation. 1ST. Chapman. 54. Chapman's Anti-dyspeptic Pills. R. Pulveris Aloes Socotrinas, Mastiches, aa 5ss; Pulveris Ipecacuanhas gr. x ; Olei Foeniculi fflviij. Fiat massa, et divide in pilulas xx. Signa. — Take one pill every night at bedtime. 50 CATHARTICS. These are indicated in cases of dyspepsia attended by habit- ual constipation. 1ST. Chapman. 55. Pills of Aloes and Gentian. R. Pulveris Aloes Capensis 3j ; Extracti Grentianas 3ss; Olei Cari gtt. x ; Syrupi q. s. ut fiat massa, in pilulas singulas grana qua- tuor pendentes, dividenda. Signa. — Take two or three pills for a dose. The addition of a tonic increases the purgative action of aloes, and diminishes its tendency to griping. 66. JP ills of Aloes, Guaiac, and Rhubarb. B . Pulveris Guaiaci Eesinae 3j ; Pulveris Aloe's Capensis gr. xxxvj ; Pulveris Ehei 3ij ; Terebinthinas Canadensis quantum sufncit ut flat massa in pilulas xlviij dividenda. Signa. — One to be taken every three hours. This combination forms a highly stimulating cathartic. 57. Pills of Rhubarb and Sulphate of Iron. R. Pulveris Ehei 3jss ; Ferri Sulphatis exsiccatae 3ss ; Saponis 9ij. Aquas destillatas q. s. ut fiat massa in pilulas xl dividenda. The intention of these pills is to remove costiveness, and impart tone to the bowels. Three may be taken for a dose at bedtime. S. P. Griffitts. 58. Pills of Ox Gall. R. Fellis Bovini inspissati 3ij ; Olei Cari gtt. x ; Magnesias Carbonatis q. s. ut fiat massa in pilulas xxxvj dividenda. Signa. — Take two pills three times daily. Clay. CATHAKTICS. 51 Confections and Electuaries. 59. Lenitive Electuary and Cream of Tartar. R. Confectionis Sennae lij ; Confectionis Aurantii Corticis 3ij 5 Potassse Bitartratis 3ij- Mi see, et fiat electuarium. Signa. — Take a piece the size of a marble, night and morning. Used in habitual constipation. 60. Confection of Senna, Sulphur, and Nitre. R. Sulphuris loti sjss ; Confectionis Sennae §ij ; Potassas Mtratis 3j ; Syrupi Aurantii Corticis q. s. ut fiat confectio. Signa. — One or two drachms to be taken twice a day. Used in hemorrhoidal affections. 61. Electuary of Jalap, Nitre, etc. R. Pulveris Jalapae, Potassae Bitartratis, Potassse Nitratis, aa Iss ; Confectionis Sennae |j ; Syrupi q. s. ut fiat electuarium. Signa. — A bolus the size of a hazel-nut may be taken three times a day. This preparation once gained considerable celebrity as a popular remedy for hemorrhoids. Emulsions and Mixtures. 62. Castor Oil, or "Oleaginous" Mixture. R. Pulveris Acacias, Pulveris Sacchari, aa 3iij ; Aquae f^ij. Tere simul, et adde gradatim — Olei Ricini §j. Dein adde, Aquae Cinnamomi fjj. Misce secundum artem. Signa. — Take a tablespoonful every two hours. This is one of the least disagreeable modes of administering this nauseous but valuable medicine. 52 CATHARTICS. 63. Another Form for Children. R. Olei Eicini 3ij; Y itellum unius ovi ; Aquae Foeniculi, Aquae Menthae Viridis, aa flj. Fiat emulsio. Signa. — Give a teaspoonful morning and night to a child three months old. 64. Mixture of Oil of Turpentine. R. Olei Terebinthinae f Jj ; Pulveris Acacias, Sacchari, aa 3ss; Aquae Menthae Piperitae f siv. Misce. Signa. — A tablespoonful every two hours until it operates. This preparation must be made in the same manner as the oleaginous mixture. 65. Oleaginous Mixture with Oil of Turpentine. R. Olei Eicini ^jss; y itellum unius ovi; Sacchari 3ij ; Olei Terebinthinae Iss; Aquae Menthae Piperitae f^iv. Misce secundum artem. Signa. — A large tablespoonful may be taken every hour or two. This preparation is much used by some of our best practi- tioners in cases requiring a brisk and stimulating cathartic. It has also been recommended as a purgative after the effects of an overdose of opium have been partially subdued by pre- liminary remedies. B. Ellis. 66. Mixture of Croton Oil. R. Olei Tigliiniij; Mucilaginis Acaciae, Aquae destillatae, aa f 3j. Misce. Signa. — -Take a teaspoonful every two hours until it operates. 67. Saponaceous Mixture of Croton Oil. R. Olei Tiglii niviij; Potassae gr. vj ; Aquae destillatae f3ij. Fiat solutio. Signa. — From three to six drops may be given for a dose, CATHARTICS. 53 This is a substitute for the soap of croton oil proposed by the French, which is more troublesome to make. Mr. Conwell states that four drops of croton oil rubbed on and around the umbilicus, will produce a cathartic effect ; even the odor of it has been known to excite the alimentary canal, either as an emetic or purgative. 68. Solution of Epsom Salt and Tartar Emetic. R. Magnesias Sulphatis 3j ; Antimonii et Potassas Tartratis gr. ss; Aquas destillatas f ^ iij ; Succi Limonis recentis f ij. Misce, et fiat solutio. A tablespoonful to be given every two hours until it ope- rates. Or one-half may be taken as a purgative dose. 69. Solution of Epsom Salts with Jalap and Nitric Acid. R. Magnesias Sulphatis 3 ss ; Tincturas Jalapas f3j ; Acidi Nitrici gtt. ij ; Aquas Menthas Yiridis foij. Misce. Signa. — To be taken for a draught. The nitric acid destroys in part the bitter taste of the salt. 70. Mixture of Magnesia and Rhubarb. R. Magnesias 3ss ; Pulveris Ehei gr. ij ; Sacchari 3j ; Spiritus Menthas Piperitas gtt. vj ; Aquas destillatas fjjss. Fiat mistura. Signa. — A teaspoonful to be given every two hours to chil- dren, until it operates. This preparation is designed for the bowel complaints of children, in which it is very serviceable. Laudanum can be added according to the age and condition of the patient. 71. Mixture of Magnesia and Colchicum. R. Magnesias 3j ; Sacchari, Pulveris Acacias, aa 3j ; Aquas destillatas fjiv; Yini Colchici Eadicis gtt. xl. Fiat mistura. Signa. — Take a tablespoonful every two hours until it ope- rates. 54 CATHARTICS. This preparation is much used in gouty and rheumatic affec- tions. Laudanum can be added if requisite. 72. Scudamore 's Mixture. R. Magnesias 9iv ; Magnesias Sulphatis oj ; Aquas Menthas Viridis f Ev ; Aceti Colchici f^ss ; Syrupi fsj. Fiat mistura. Dose, a tablespoonful every two hours. Chiefly used in gouty paroxysms. Sir C. Scudamore. 73. Acid Solution of Ver atria. R. Veratrias gr. j ; Acidi Sulphurici Aromatici gtt. v ; Aquas destillatas fjij. Fiat solutio. Dose, a teaspoonful. This solution is said to be a good sub- stitute for the Eau Medicinale of Husson, in gouty affec- tions. Magendie. 74. Mixture of Fluid Extract of Butternut. R. Extracti Juglandis Fluidi (Thayer) f3ij ; Syrupi Zingiberis f3ij ; Aquas f^ss. Misce. Signa. — Take one-half as a draught. The butternut is a mild cathartic, operating usually without pain or griping. It is adapted to cases of habitual constipa- tion. 75. Purgative Mineral Water. R. Liquoris Magnesias Citratis flxij. Signa. — Take a teacupful every two hours until it operates. From its resemblance to lemonade in taste, this constitutes one of the most pleasant laxatives now in use. A child five years old, may take a wineglassful as a dose. The country practitioner can make a good approximation by neutralizing carbonate of magnesia with citric acid, in the proportion of fourteen parts of the former to twenty parts of the latter, and flavoring the solution with lemon syrup. Half an ounce of the neutral salt of citrate of magnesia constitutes a dose. CATHARTICS. 55 76. Purgative Soda Water. R. Sodae Carbonatis Crystallisatae $ix] Acidi Tartarici 3yj ; Aquae f ox; Syrupi Limonis f ,Ijss. Misce in ampulla vitrea et adjice — ■ Sodas Bicarboxiatis 3ss. Signa. — To be taken by draughts of a wineglassful every two hours. Prof. J. Lawrence Smith published a formula for purgative soda water, as prepared by him on a large scale, from which the above is condensed. As a purgative, it is mild and cer- tain, producing watery evacuations. 77. Fluid Extract of Senna, Ginger, etc. R. Extracti Sennae fluidi f3ij ; Extracti Ehei fluidi f 3j ; Syrupi Zingiberis f3v; Aquae fsj. Misce. ■Signa. — Dose, a tablespoonful. This is an efficient mixture, operating without much pain. The dose should be repeated every four hours until a purga- tive effect is produced. Infusions and Decoctions. 78. Infusion of Senna and Salts. — Black Draught. R. Sennae, Menthae Viridis, aa gss; Aquae bullientis Oj. Macera per horam unam, cola, et adde — Magnesias Sulpha tis iij. Solve. Signa. — Administer a wineglassful every two hours, until purgation is produced. Guy's Hosp. 79. Infusion of Senna and Manna. R. Sennae 3yj; Mannae 3ss; Cardamomi 3ij ; Aquae bullientis f Iviij. Macera per horam unam et cola. Signa. — One-half to be taken at a draught ; and if insufficient, the remainder in two or three hours. 56 CATHARTICS. 80. Decoction of Prunes and Senna. R. Pruni .liij ; Infusi Sennas Ojss. Coque ad Oj, et cola. Signa. — Dose, a wineglassful at bedtime. In making this decoction, the coriander seed, directed in the officinal infusion of senna, had better be omitted until near the close of the process. This forms a good laxative for pregnant women. Sugar enough to make a syrup im- proves the taste. 81. Infusion of Senna, Rhubarb, and Manna. R. Sennas 3vj ; Mannas %iv ; Ehei contusi, Cardamomi, aa 5ij ; Aquae bullientis Oj. Macera per horam unam et cola. Signa. — Dose, a wineglassful every two hours, until it ope- rates. 82. Alkaline Mixture of Aloes. R. Aloes Capensis ^ijss ; Sodas Bicarbonatis 3vj ; Aquas Oiv; Spiritus Lavandulas Compositi f .1 ij. Misce. Macera per dies quatuordecim et cola. Signa. — Dose, a teaspoonful after each meal. This is an excellent preparation for Hospital or Dispen- sary practice. It is particularly serviceable in cases of dyspepsia, attended with acidity of the stomach and torpor of the liver and bowels. J. P. Mettauer. Wines and Tinctures. 83. Wine of Golchicum Root and Laudanum. R. Yini Colchici Eadicis f 3jss ; Tincturas Opii f 3ij - Misce. Signa. — Give twenty drops every three hours. The preparations of colchicum often occasion vomiting and purging, if given alone; but when combined with small quantities of opium or morphia, as above, these effects are ENEMATA. 57 prevented, while the specific property of colchicum to control gout and rheumatism seems to be increased. Eisenman. 84. Tincture of Elaterin. R. Elaterin gr. j ; Alcoholis f Ij. Solve ; dein adde — Acidi Nitrici gtt. iv. Misce. Signa. — Dose, twenty to forty drops in a tablespoonful of cinnamon water. Used as a hydragogue cathartic in drop- sies. Mokeies. Enemata. Enemata, used either as auxiliaries to, or substitutes for cathartics, very properly succeed that class of remedies. They are employed to fulfil other indications, and the different preparations will be noticed under their appropriate heads. It is usual to direct three times the quantity of the medicine to be given for an enema that is required for a dose by the mouth. For the purpose of procuring a discharge from the bowels, this rule may generally be observed ; but in some of the powerful remedies occasionally administered, as opium and tobacco, it might be attended with serious conse- quences. "When using these active drugs, it is better to give only double the quantity. The bulk of the enema also varies according to the object we have in view. If purgation is to be effected, the subjoined proportions afford a good rule; but if the remedial agent is to be retained for some time, a small amount is obviously indicated, lest the mere bulk of the injection cause an imme- diate discharge. The following are the proportions recommended by Pro- fessor Chapman in the ordinary enemata for persons of dif- ferent ages : A child between the ages of one and five years, from f ^iv to f Jvj. A youth of ten or fifteen years, half a pint ; and an adult, from a pint to a quart, according to circum- stances. In all cases, a warm folded towel should be firmly pressed against the anus for fifteen minutes after the injection is thrown up. The facility with which an enema is administered may be very much increased by attending to certain precautions, viz : 1. Introduce the finger, thoroughly lubricated with soap or 58 ENEMATA. lard, into the rectum, as a guide to the pipe. 2. Pass the pipe backward and toward the left side, in the course of the rectum. 3. Introduce the injection slowly, so as not to sur- prise the bowel by a sudden distension, causing it to contract as suddenly and eject the fluid. 85. Castor Oil, Molasses, and Salt Enema. R. Olei Eicini fiij ; Syrupi Fusci fsij ; Sodii Chloridi ,?j ; Infusi Lini tepidi Oj. Fiat enema. One-half to be administered at once, and the remainder in half an hour, if the first produces no evacuation. The chloride of sodium is an active ingredient. In fact, there is no better enema than simple salt and water at the ordinary tempera- ture ; and sea- water fresh from the ocean answers the same purpose. 86. Soap Enema. R. Saponis Vulgaris incisi ^j ; Infusi Lini tepidi Oss. Misce pro enemate. This is an effectual clyster in cases of flatulence and im- pacted feces. 87. Ox Gall Enema. R. Fellis Bovini spissati 5ij ; vel Fellis Bovini recentis f^j ; Aquse tepidge Oj. Misce. Signa. — Use for an injection, in cases of obstinate constipa- tion and hardened feces. 88. Enema of Oil of Turpentine. R. Olei Terebinthinee foss ; Yitellum unius ovi. Terre simul, et adde, gradatim, Decocti Hordei tepidi f.?x. Used as a stimulating injection. Guy's Hospital Phaem. SUPPOSITORIES. 59 89. Enema of Senna and Epsom -Salts. R. Infusi Sennse Oj ; Magnesiae Sulphatis 3ij. Misce. — One-half to be exhibited as an enema, and the re- mainder, if necessary, in half an hour. 90. Enema of Tobacco. R. Tabaci 3j ; Aquae bullientis Oj. Macera per sextain horse partem et cola. One-quarter or one-half of this infusion may be used as an injection ; and, if necessary, the same quantity may be given in half an hour. Employed for strangulated hernia, obstinate colic, spasm of the urethra, and for the reduction of disloca- tions. Guy's Hospital Pharm. Suppositories. (From Siipponere, to put under.) Suppositories constitute a class of remedies that has hitherto been little used by American practitioners. They are solid ; round, cylindrical, or conical in form ; and intended for intro- duction into the anus. They are prepared by mingling seda- tive, astringent, or purgative medicines with cocoa-butter, suet, soap, or thick honey. When made with suet or cocoa-butter, these substances should be melted, at a gentle heat, with an eighth or a twelfth of white wax, according to the season of the year. The medi- cinal agent is added, and the fluid mass poured into metallic cones to cool and become solid. A suppository should weigh from twenty grains to two drachms, and be as large as the end of the little finger. Purgative suppositories are larger than those of an anodyne character. By the heat of the body, the suet or cocoa-butter is softened, and the remedial agent is thus permitted to develop its effects. Soap suppositories are formed by cutting soap into conve- nient shapes. Suppositories with honey are prepared by boil- ing down this substance till it becomes sufficiently thick to retain its shape when cool. Laxative suppositories being rarely, if ever, used for adults, formulae for this purpose are unnecessary ; for other indications they will be found in their appropriate places. For children, suppositories of soap or molasses candy are often of great use. CLASS IV. DIUEETIOS. The rules for. the administration of this class of remedies are few and simple. Where there is much arterial excitement, a judicious use of the lancet may precede the employment of diuretics, and the patient be kept cool to avoid perspiration. In order to insure the full effect of diuretics, diluent drinks should be freely given, and especially those containing some diuretic medicine. Powders. 91. Powder of Squill and Nitre. R. Pulveris Scillse gr. vj ; Potassse Nitratis 3j- Misce, et fiant pulveres vj. Signa. — One to be given three times a day in sugar and water. Some aromatic, such as cinnamon, may be added to this pre- paration if the stomach is irritable. Employed in dropsies. 92. Powder of Nitre, Cream of Tartar, and Tartar Emetic. R. Potassas Nitratis iss ; Potassas Bitartratis 3iv ; Antimonii et Potassae Tartratis gr. j. Tere simul et flat pulvis. Signa. — Take a teaspoonful three times daily. This combination is designed for cases of acute gonorrhoea. The free administration of saline diuretics in this disease often effects permanent cures. J. Weill. DIURETICS. 61 93. Powder of Uva Ursi and Soda. R. Pulveris Uvae Ursi 3jss; Sodae Bicarbonatis 5j« -Misce, et divide in chart ulas xij. Signa. — One three times a day in sugar and water. In nephritic complaints and affections of the bladder. 94. Powder of Ergot and Cubebs. R. Pulveris Ergotae Bij ; Pulveris Cubebae 3j ; Pulveris Cinnamomi Jss ; Sacchari 5j- Divide in pulveres viij. Signa. — One may be given three times a day. In leucorrhcea and gleet. * Dr. Ryan. 95. Powder of Squill, Cream of Tartar, etc. R. Antimonii et Potassae Tartratis gr. ij ; Pulveris Scillas 3j ; Potasses Bitartratis 3jss ; Potassae Sulphatis Iss. Fiat pulvis, et divide in pulveres xx. Signa. — Take one powder four times daily. This combination produces copious watery stools, together with a considerable now of urine ; properties that render it valuable in cases of general dropsy. Eberle. 96. Powder of ColcMcum, and Cream of Tartar. R. Pulveris Colchici radicis 3ss ; Potassae Bitartratis 3ij- Misce, et divide in pulveres vj. Signa. — One powder every four hours. This combination is very serviceable in acute rheumatism, Purging usually results from its employment. Sometimes the pulse becomes slow or irregular. J. Jackson. Pills. 97. Pills of Squill and Calomel. R. Hydrargyri Chloridi Mitis, Pulveris Scillae, aa gr. xij ; Confectionis Rosae q. s. ut fiant pilulae xij. Signa. — One night and morning, in dropsies depending upon visceral derangement. 62 DIURETICS. This preparation is one of the most celebrated of the diu- retics, especially when disease of the liver is the cause of effu- sion. When the calomel affects the month it should be omitted, and the squill combined with some other diuretic. [98. Pills of Digitalis, Podophyllin, and Iron.'] R. Digitalis Pulveris gr. xij ; Podophyllin gr. j ; Ferri Perchloridi gr. xij. Syrupi Acacias q. s. Misce, et divide in pilulas xij. Signa. — One pill to be taken every three or four hours. In the dropsy following intermittent fever or in anaemic conditions. 99. Pills of Digitalis, Calomel, and Opium. R. Pulveris Digitalis gr. xij ; Hydrargyri Chloridi Mitis gr. vj ; Pulveris Opii gr. iv ; Confectionis Rosas q. s. ut flant pilulas xij. Signa. — One to be taken every eight honrs. In hydrothorax and ascites. 100. Pills of Copaiba and Cubebs. R. Ceras flavas gr. xv. Liqnefac cum leni calore, dein adde — Copaibas gr. xxx ; Pulveris Cubebas 3j- Misce intime, et divide in pilulas xxx. Signa. — Two pills every four hours. This furnishes a good mode of exhibiting copaiba and cubebs in small quantities, as in chronic diseases of the bladder, or irritability of the nrethra. J. M. Maisch. 101. Pills of Extract of Dandelion and Blue Mass. R. Extracti Taraxaci 3ss; Pilulas Hydrargyri gr. x. Misce, et riant pilulas x. Signa. — One to be taken morning, noon, and night. In dropsy complicated with disease of the liver. DIURETICS. 63 102. Granules of Di gitalin. R. Digitalini gr. j ; Sacchari 3j ; Aquas q. s. Fiat massa, et divide in pilulas lx. Signa. — Take one granule four times daily. Prescribed in dropsy as a substitute for digitalis. Homolle. 103. Pills of Digitalis, Squill, and Juniper. R. Pulveris Digitalis 9j ; Pulveris Scillas 3ss ; Olei Juniperi gtt. viij ; Syrupi q. s. ut fiat massa, in pilulas xij dividenda. Signa. — Take one pill three times daily. Used in dropsy. Peakson. 104. Pills of Digitalis, Squill, and Blue Mass. R. Pulveris Digitalis gr. v ; Pulveris Scillas gr. x ; Pilulas Hydrargyri 3ss. Fiat massa, et divide in pilulas x. Signa. — Take one pill three times daily. This combination was highly recommended by the late Dr, Baillie, of London, as an alterative and diuretic in anasarca. Infusions and Decoctions. 105. Infusion of Digitalis and Sweet Spirit of Nitre. R. Digitalis 3j ; Aquas bullientis Oss. Macera per horas tres, cola, et adde — Spiritus JEtheris Nitrosi, f oj. Signa. — Dose, for an adult, half a tablespoonful three times a day. The prostrating effect of digitalis should always be kept in mind by the practitioner ; and the rule, that when it acts upon the stomach, the bowels, the pulse, or the kidneys, it should be discontinued, cannot, when we consider the power of the article, be too scrupulously observed. B. Ellis. 64 DIURETICS. 106. Infusion of Juniper Berries and Cream of Tartar. B. Juniperi contusi ^iv; Aquas bullientis f ,?xij ; Spiritus Juniperi (Holland Gin), f^iv. Macera per horas duodecim et exprime. Signa. — Take a wineglassful, mixed with a teaspoonful of cream of tartar, three times a day. This is an excellent mode of administering a favorite diu- retic, in cases of dropsy, in which a little stimulation would be admissible. W. Procter, Jr. 107. Infusion of Parsley Root. B, Petroselini lj; Aquas bullientis Oj. Fiat infusum et cola. A teacupful may be taken with a teaspoonful of sweet spirit of nitre, every three or four hours. A popular and very useful remedy for strangury, arising from blisters. It is also an efficient diuretic in dropsies. 108. Infusion of Dandelion, etc. B. Infusi Taraxaci fsiv; Extracti Taraxaci 3ij 5 Sodas Carbonatis 3ss; Potassas Tartratis 3iij ; Tincturas Ehei f 3iij ; Tincturas Hyoscyami gtt. xx. Fiat mistura. Signa. — One-third part to be taken three times a day. In dropsical and visceral affections. C. D. Meigs. 109. Decoction of Indian Hemp. B. Apocyni Cannabini 5ss; Aquas Ojss. Coque ad Oj, et cola. Signa. — Take a wineglassful three times a day. This has been found useful in general dropsy, acting as a hydragogue cathartic, and as a diuretic. The diuretic pro- perties of the decoction will be increased by the addition of an ounce of juniper berries to each pint. G-riscom. The young practitioner must carefully distinguish between preparations of the native drug under consideration (Apocy- DIURETICS. 65 num Cannabinum), and the powerful, imported extract of Cannabis Sativa; as, unfortunately, they both bear the same trivial name of Indian Hemp. 110. Decoction of Pareira Brava Root. R. Pareira? contusse Iss; Aquss bullientis Oiij. Coque, leni calore, ad Oj, et cola. Signa. — Take a wineglassful every two hours. " Pareira Brava has a great influence over chronic inflam- mation of the bladder, lessening very materially the secretion of the ropy mucus, which is itself a very great evil, and, I believe, diminishing the inflammation and irritability of the bladder also." . Sir B. Brodie. Solutions and Mixtures. [111. Liquor Potass se in Milk.] R. Liquoris Potassaa gtt. xx; La'ctis recentis f^ij. Fiat haustus. To be taken every two or three hours until relieved. In dysury, irritation of bladder, and frequent micturition from acrid and concentrated urine; useful in the albuminuria of pregnancy. 112. Cider Mixture. R. Juniperi contusi, Sinapis, Zingiberis, aa jfss; Armoracise contusas, Petroselini, aa oj ; Succi fermenti pomorum Oij. Macera per diem unam, et cola. Signa. — A wineglassful may be taken three or four times a day. The above compound was recommended by the late Dr. Jos. Parrish, in cases of general dropsy which admit of stimu- lation, and in which the urinary secretion is deficient. The cider should be old and sound. 5 bb DIUEETICS. 113. Mixture of Oil of Juniper. B. Olei Juniperi f 5ss ; Spiritlis JEtheris Mtrosi, Tincturae Digitalis, aa f 5iij. Misce. Signa. — Give thirty drops every three hours. This is the formula of the " diuretic drops" celebrated in Germany as a diuretic remedy, and used in all cases in which medicines of this class are indicated. Hufelaxd. 114. Diuretic Wine. R. Juniperi contusi 3 x ; Pulveris Digitalis 3ij ; Pulveris Scillse 3j ; Yini Xerici Oj. Macera per dies quatuor, et adjice — Potassae Acetatis oiij. Exprime et coia. Signa. — Dose, a tablespoonful three times daily. This preparation is employed in " l'Hotel Dieu de Paris," and is found to be an efficient diuretic. Tkousseau. 115. Mixture of Juniper, Squill, etc. B. Potassae Acetatis 3v; Potassae Bicarbonatis 3j ; Aquas f^xij; Tincturae Scillas f 3j ; Spiritus Juniperi Compositi f^j. Fiat mistura. Signa. — Take two tablespoonfuls three times a day. Employed in dropsy. Beown. 116. Mixture of Digitalis, Acetate of Potassa, etc. B. Infusi Digitalis f^iv ; Potassae Acetatis 3ij ; Spiritus ^Etheris Nitrosi f 3ij ; Aquae Cinnamomi f Jjss. Eiat mistura. Signa. — Take a tablespoonful every four hours. Eecommended in the treatment of dropsy supervening upon cardiac disease. Kilgoue. DIUKETICS. 67 117. Mixture of Caniharides and Sweet Spirit of Nitre. R. Tincturae Cantharidis, Spiritus iEtheris Nitrosi, aa gtt. lx ; Sacchari 3j ; Aquae Menthae Yiridis f^ij. Fiat mistura. Signa. — A teaspoonful may be taken every three hours, de- sisting if strangury should supervene. A stimulant diuretic. Used in atony of the bladder. 118. Mixture of Oil of Turpentine. R. Olei Terebinthinae n^c; Pulveris Acacias, Sacchari, aa 3j ; Aquae Menthae Viridis f 3iv. Fiat mistura. Signa. — A tablespoonful four or five times a day, aided by some diuretic drink. This remedy is used with great benefit in nephritic com- plaints, and especially in the passage of calculi through the ureters. 119. Mixture of Benzoic Acid, etc. R. Acidi Benzoici 9iv; Spiritus Juniperi Compositi flss; Syrupi Tolutani f Jjss ; Aquae f^ij. Fiat mistura. Signa. — Give a dessert- spoonful every four hours. This combination is recommended in the phosphatic variety of gravel. It is also useful in the treatment of diabetes. [120. Another Form.] R. Acidi Benzoici 3ij ; Potassae Bicarbonatis Sss ; Spiritus JEtheris Nitrosi f 3j ; Syrupi Limonis f ^ij ; Liquoris Ammonias Acetatis f^iij. Misce. Signa. — A tablespoonful to be taken four or five times daily. An excellent combination in the albuminuria of preg- nancy. b« DIUKETICS. 121. Mixture of Ulaterium, Colchicum, etc. B. Elaterii gr. j ; Spiritus iEtheris ISTitrosi f Sij ; Tincturas Scillas f Iss ; Aceti Colchici f 3ij ; Syrupi fSj. Fiat mistura. Signa. — Take a teaspoonful four times a day in a little water. Dr. Ferriar recommends the above in the several forms of dropsy, and more especially in hydrothorax. 122. Tincture of Colchicum and Digitalis. B. Tincturas Colchici, Tinctures Digitalis, Spiritus JEtheris Nitrosi, aa f 3j. Misce. Signa. — Dose, twenty drops on a lump of sugar. Given as a diuretic in dropsy and hydrothorax. HlLDENBRAND. 123. Mixture of Citrate of Potassa, Squill, etc, B. Potassas Carbonatis Purae 3j ; Succi Limonis q. s. ad saturandum ; Tincture Scillas f ^ss ; Tincturas Opii "Ixxx ; Aquas Cinnamomi f £iv. Misce. /Signa. — A tablespoonful every three hours throughout the day. The vinegar or oxymel of squill, if preferred, may be sub- stituted in this preparation. We use the tincture because it is more uniform, and less liable to spontaneous changes. 124. Mixture of the Acetate of Potassa, and Spirit of Minder er us. B. Liquoris Ammonias Acetatis f Jij ; Potassas Acetatis Sij- Misce. Signa. — A tablespoonful every three hours for a dose, Kecommended for gravel and lithic acid deposits. DIUEETICS. 69 125. Mixture of Buchu and Acetate of Potassa. R. Extracti Buchu Fluidi f^ss; Potassas Acetatis 3ij ; Syrupi f 3jss ; Aquas f 3iv. Misce. Signa. — A tablespoonful every four hours. This is an excellent diuretic combination, and its value may be farther enhanced by the addition of sweet spirit of nitre. MOETON". 126. Mixture of Buchu and Uva Ursi. R. Extracti Buchu Fluidi, Extracti Uvas Ursi Fluidi, aa f 3ij ; Syrupi Acacias f 3ss ; Aquas Menthas Yiridis f Jjj. Misce. Signa. — A dessert- spoonful every three hours. Used in blennorrhosa, atony, and paralysis of the bladder. 127. Mixture of Copaiba. R. Copaibas Iss; Spiritus iEtheris Mtrosi f Iss ; Pulveris Acacias 3ij ; Sacchari 3j ; Aquas destillatas fliv; Spiritus Lavandulae Compositi f 3ij ; Tincturas Opii f3j. Fiat mistura secundum artem. Signa. — A tablespoonful three times a day. Chapman. This remedy is more especially used in gonorrhoea, and is considered by Professor Chapman as a specific in that dis- ease. A preferable mode of exhibiting balsam copaiba, con- sists in dropping the quantity prescribed for a dose in a wineglass of water, and then adding to it a small quantity of the compound tincture of gentian. The balsam collects into a globule and is surrounded by the tincture, which, leaving its taste in the mouth, covers that of the nauseous balsam. B. Ellis. 70 DIUEETICS. 128. Mixture of Copaiba, Cubebs, etc. R. Copaibas, Pulveris Cubebas, aa 3ss; Acacias, Sacchari, aa 3ij ; Aquas f Hvij ; Tincturas Opii Campboratas f 3ss. Misce secundum artem. Signa. — A tablespoonful every tbree bours. "We bave found tbis remedy, in some obstinate cases of gonorrhoea, more efficacious than tbe preceding formula. Tbe tincture of cubebs may be substituted for tbe powder, if desirable. Balsam copaiba is sometimes given by tbe French pbysicians in tbe form of enema, for tbe cure of gonorrhoea. Capsules containing it are also in common use. S. G. Moeton. 129. Another Form. R. Copaibas ^jss; Mucilaginis Acacias flv; Olei Limonis, gtt. vj ; Tincturas Cubebas f ^j : Spiritus ^Etberis Nitrosi f 5ss. Fiat mistura. Signa. — Take a tablespoonful tbree times a day, in gonor- rhoea. J. Eandolph. 130. Compound Mixture of Copaiba. R. Olei Copaibas f3j ; Alcobolis, Aquas Mentbas Piperitas, Syrupi, aa f^ss; Spiritus ^Etheris Mtrosi f 5ss. Fiat mistura. Signa. — To be taken during tbe day in four doses, followed by demulcent drinks. In cbronic gonorrhoea. DIURETICS. 71 131. Another Form. {Lafayette Mixture.) R. Copaibas Ij ; Liquoris Potassas f 3ij. Tere simul et adjice — Spiritus iEtheris Nitrosi f *j ; Spiritus Lavandulae Compositi f lij ; Syrupi Acacias f Jiv. Misce. Sigria. — A tablespoonful three times a day. Used in gonorrhoea. 132. Mixture of Fluid Extract of Cubebs. R. Oleoresinas Cubebas f 3ij ; Syrupi Acacias, Syrupi Tolutani, aa f Iss ; Spiritus iEtheris Nitrosi f3ij. Aquas f sijss. Fiat mistura. Signa. — Give a tablespoonful every three hours. Used in gonorrhoea. Thomas. CLASS Y. AXTILITHICS A3D LITHOXTEIPTIOS. Aktilithics are those substances which 'arrest or prevent the formation of stone in the kidneys or bladder. Lithontrip- tics are supposed to possess the power of dissolving calculous concretions, by acting on the substance which serves as the bond of union to the saline or acid particles composing the stone. To administer these remedies with any degree of success, requires a chemical knowledge of the ingredients which enter into the formation of the different kinds of stone ; attention must also be given to the properties of the urine. As derangement of the digestive organs almost always co- exists with these foreign bodies in the urinary apparatus, we shall gain a very considerable advantage by combining the remedies of this class with those which have a tendency to restore the healthy action of the stomach and bowels. When lithic or uric acid abounds in the urine, the alkalies will be found to produce the greatest benefit ; but where the salts are evidently of the phosphatic or magnesian character, the muriatic acid, or some one of the mineral acids, will con- stitute the most appropriate remedy. Powders and Pills. 133. Powders of Uva Ursi, Barh, and Opium. R. Pulveris Uvas Ursi, Pulveris Cinchonas Flavas, aa 3ij ; Pulveris Opii gr. iij. Misce, et divide in chartulas vj. — Of which one may be taken three or four times a day. ANTILITHICS AND LITHONTRIPTICS. 73 The above is the original prescription of Dr. Ferriar, for urinary deposits, who advises the patient to drink two ounces of lime-water after each dose. It is designed to give tone to the digestive and urinary apparatus, and thereby to prevent the further formation of stone. 134. Pills of Carbonate of Soda and Soap. R. Sodas Carbonatis exsiccatas, Saponis, aa 3j ; Extracti Glycyrrhizas, Aquas, aa q. s. ut flat massa in pilulas xxx dividenda. Signa. — Take three pills, three times a day. Prescribed when uric acid deposits are found in the urine, Beddoes. Solutions, Mixtures, etc. 135. Solution of Potassa, Tincture of Hops, etc. R. Liquoris Potassas f ^ss ; Tincturas Humuli f.^jss; Infusi Calumbas f liv ; Syrupi Aurantii Corticis f 3ij. Fiat mistura. Signa. — Take a tablespoonful three times daily. Employed in cases where the urine indicates an excess of uric acid. H. Green. 136. Solution of Bicarbonate of Soda, etc. R. Sodas Bicarbonatis 3j ; Infusi Quassias f iiv ; Tincturas Calumbas Oj. Misce. Signa. — A tablespoonful four times a day. Used in the same cases as the preceding. 137. Mixture of Bicarbonate of Soda, etc. R, Sodas Bicarbonatis 5j ; Misturae Amygdalae f^iv; Copaibas f 3ij ; Tincturae Opii gtt. lx. Fiat mistura secundum artem. Signa. — A tablespoonful every three hours. In acute pain of the bladder. 74 ANTILITHICS AND LITHONTRIPTICS. r In combination "with each of these alkaline preparations, demulcent drinks may with benefit be freely employed. 138. Fluid Extract of Hydrangea Arhorescens. R. Eadicis Hydrangeas contusi ^xvj ; Aquae bullientis Ovj. Coque ad Oss, cola, et adjice — Mellis Oij. Coque ad Ojss, et adjice — Spiritus Yini Gallici Oss. Signa. — Dose, a teaspoonful three times daily. This formula is furnished by Mr. Edward Parrish, based on one devised by Dr. S. W. Butler, who first called the atten- tion of the profession to the valuable properties of this root. In chronic catarrh of the bladder and gravel it has proved highly beneficial, as also in cases of stone. Indeed, in some instances, small stones have been passed during its employ- ment. Dr. W. L. Atlee, of Philadelphia, and Dr. J. C. S. Monkur, of Baltimore, report favorably of its use in cases of earthy deposits in the urine. 139. Mixture of Carbonate of Magnesia and Gentian. R. Magnesia Carbonatis 5j ; Infusi Grentianae Compositi f^vj. Fiat mistura. Signa. — A wineglassful to be taken three times a day. This mixture is recommended by Mr. Brande, of London, as superior to the alkalies, in cases where uric acid abounds. [140. Mixture of Nitro-hydrochloric Acid.'] R. Acidi Mtro-hydrochlorici diluti f oij ; Tinctures Grentianae f 3iij ; Tincturae Aconiti foliorum "Ixxx ; Syrupi Aurantii f Ej ; Infusi Aurantii ad f Iviij. Misce. Signa. — Take one-sixth part three times daily. In oxaluria. T. H. Tanner. ANTILITHICS AND LITHONTKIPTICS. 75 [141. Mixture of Iron and Hydrochloric AcidJ] R. Tincture Perri Chloridi f3ij ; Acicli Hydrochlorici diluti f 3ss ; Syrupi f .lijss ; Aquae f^iij. Misce. Signa. — A tablespoonful four times daily, rinsing the mouth well after it. Oxaluria, with anemia and nervous atony. 142. Mixture of Muriatic Acid. R. Acidi Hydrochlorici diluti f 3j ; Decocti Hordei f Jviij. Misce. Signa. — Dose, a tablespoonful largely diluted three times a day. Prescribed for the prevention of phosphatic deposits in the urine. Nitric acid has been given with the same intention, but appears to be less useful than muriatic. 143. Mixture of Phosphoric Acid. R. Acidi Phosphorici diluti fiss; Infusi Calumbse f^vij; Tincturse Cardamomi Compositse f Iss. Piat mistura. Signa. — A tablespoonful in sweetened water every four hours. Used to correct phosphatic deposits in the urine. Neligan. 144. Mixture of Oil of Turpentine and Ether. R. Olei TerebinthinaB, iEtheris, aa f 3iv. Misce. Signa. — A large teaspoonful to be taken on sugar every half hour until relief is obtained. Oil of turpentine has been frequently given of late in the passage of urinary concretions down the ureters. It is stated by Dr. Physick that this remedy, proportioned in its dose to the degree of suffering, affords more prompt relief than any other. 76 ANTILITHICS AND LITHONTRIPTICS. 145. Injection of Carbonate of Soda. R. Soclae Carbonatis 3j; Saponis 3ij ; Aquae destillatae f 3xij. Fiat solutio et cola. Signa. — Use as an urethral injection, for softening uric acid deposits. Hopital de Montpellier. 146. Injection of Carbonate of Lithia. R. Lithias Carbonatis 5j ; Aquae Oj. Solve. Signa. — Use as an urethral injection. Mr. Alexander Ure recommends the carbonate of lithia as an injection into the bladder for the solution of uric acid deposits. He suggests its special use for removing the sharp angular points and asperities of the broken fragments, where the practice of crushing is adopted. Dr. Garrod recommends the internal employment of carbo- nate of lithia in the uric acid diathesis, two to three grains being given in free solution three times a day. CLASS YI. DIAPHOEETICS. During the exhibition of this class of medicines the patient must be confined to his bed ; and when diaphoresis is once excited, every precaution should be taken lest it be suddenly checked. "When the skin continues steadily hot and dry, all external warmth must be removed, and cold water freely applied to the temples, hands, feet, etc., while the room is to be kept cool by a free current of fresh air. Under these circumstances, cold water may be frequently and plentifully drunk by the patient. Diaphoretics given in conjunction with these general means, will act with much more certainty than if great heat of the surface is maintained by covering the patient with heavy bedclothes. If it be desirable to produce perspiration when the heat of the skin is not above the natural standard, we shall, obtain our object most readily by placing the patient in a warm bed, giving him warm drinks freely, placing his feet in warm water, or applying hot bottles, or bags of sand, to the different parts of his body. The bags of sand accommo- date themselves to the inequalities of the surface, and therefore form an excellent mode of applying heat externally. Warm bricks, covered with cloths, and wetted with vinegar, may also be used advantageously. Employed in this way they form a steam-bath. The same effect may be produced by con- ducting the vapor of alcohol through a tube, under the bed- clothes of the patient. In a few words, then, we have described the manner of pro- ducing diaphoresis under opposite states of the system. In the first instance we solicit, in the second we rather extort it. It may be proper to observe, that in the febrile affections the frequent change of linen about the patient is not only 78 DIAPHORETICS. warrantable, but absolutely necessary, whilst employing this class of remedies. Where, however, we are desirous of producing what is em- phatically termed " a sweat" we should envelop the patient in a flannel shirt or gown, and avoid, as was before observed, every cause which may suddenly check the cutaneous dis- charge, and more especially purging and diuresis. In the treatment of ordinary fevers, we usually resort to articles recognized by the profession as being capable of pro- ducing perspiration or sweating, soon after their exhibition ; while in chronic diseases, as syphilis, scrofula, and the*cachectic state following the use or abuse of mercury, others are em- ployed which combine an alterative property with their tend- ency to the skin. It is therefore deemed advisable to make two sub-classes, viz., 1. Ordinary Diaphoretics, and 2. Altera- tive Diaphoretics. Sub-Class I.— ORDINARY DIAPHORETICS. Powders. 147. Dover's Powder, Camphor, and Saltpetre. R. Camphoras, redactas in pulverem gr. v ; Potasses Nitratis gr. xx ; Pulveris Ipecacuanhas Compositi gr. x. Tere simul et riant pulveres ij. Signa. — One powder to be taken at bedtime. This excellent diaphoretic is serviceable in febrile cases complicated with irregular nervous action. Simpson. [148. Tyson's Antimonial Powder i\ R. Antimonii Oxidi gr. j. Calcis Phosphatis gr. ix. Misce, flat pulvis subtilissimum ; divide in chartulas x. Signa. — Dose as a diaphoretic, one powder every two or three hours. From long use of this preparation the editor regards it as the most efficient and reliable of all the antimonials. If pro- perly prepared, the dose usually given in the books, three to five grains, is too large, except as an emetic. DIAPHOKETICS. 79 149. James's Powder. R. Pul vis Antimonialis, Ed. 3j. Divide in chartulas vj. Signa. — One every two or three hours in syrup or molasses. Employed in febrile conditions. 150. Nitrous Powders. B. Potassae Nitratis 3j; Antimonii et Potassas Tartratis gr. ss; Hydrargyri Chloridi Mitis gr. vj. Fiant pnlveres vj. Signa. — One to be taken every two hours in syrup or mo- lasses. In febrile affections. The calomel may be omitted or diminished, at the discretion of the practitioner. 151. Poivders of Opium, Ipecacuanha, Calomel, and Saltpetre. B. Pulveris Opii gr. iij; Pulveris Ipecacuanhas gr. vj ; Hydrargyri Chloridi Mitis gr. jss; Potassae Nitratis 3ss. Fiant pulveres vj. Signa. — One to be taken every three or four hours. This is a valuable anodyne and alterative diaphoretic. 152. Powders of Calomel, Opium, and Ipecacuanha. B. Pulveris Opii gr. iv; Hydrargyri Chloridi Mitis gr. ij ; Pulveris Ipecacuanhas gr. viij. Divide in pulveres viij. Signa. — One to be taken every two hours. This combination is recommended by Professor Chapman in dysentery. From its evident diaphoretic tendency we have been induced to place it under this head. 153. Powders of Sulphur et of Antimony, Calomel, etc. B. Antimonii Sulphurati, Hydrargyri Chloridi Mitis, aa gr. vj ; Pulveris Guaiaci Kesinae 3j. Fiant pulveres vj. Signa. — One to be taken morning and evening. 80 DIAPHORETICS. Double or even triple proportion of the ingredients may be used if necessary. Given in cutaneous diseases. 154. Soda Powder of Guy's Hospital. R. Sodas Carbonatis exsiccatse 3j; Hydrargyri Chloridi Mitis gr. xij ; Pulveris Cretas Compositi, Lond. 3ij. Misce. Signa. — Give three to eight grains at night for a week, in infantile gastric fever; followed in the morning by five grains of rhubarb mixed with ten grains of the sulphate of potassa. Dr. Fordyce says of the above: "Had I been more ambitious of dying a rich man than of living a useful member of society, the powers of our antihectic powder in curing, as if by miracle, the hectic fever and the swelled bellies of children in London, would have remained a secret while I lived." Goldhstg Bird. 155. Compound Powder of Guaiacum. R. Pulveris Guaiaci Kesinas, Potassas Mtratis, aa 3j ; Pulveris Ipecacuanhas gr. iij ; Pulveris Opii gr. ij. Fiant pulveres vj. Signa. — One to be taken every three hours in a little jelly or molasses. A stimulating diaphoretic, and particularly serviceable in acute rheumatism after the reduction of inflammatory symp- toms. Solutions and Mixtures. 156. Solution of Morphia and Wine of Ipecacuanha. R. Morphias Acetatis jj; Acidi Acetici diluti fij. Solve; dein adde — Alcoholis diluti fivij; Vini Ipecacuanhas Oij. Misce. Signa. — Dose, from fifteen to thirty drops. DIAPHORETICS. 81 157. Neutral Mixture. R. Succi Limonis recentis f^jss; Potasses Carbonatis q. s. ad saturandum; Saccliari 3ij ; Antimonii et Potassas Tartratis gr. ss ; Aquas destillatae f^iij. Misce. Signa. — A tablespoonful to be taken every two hours. This preparation is one of our most agreeable diaphoretics. Its powers are decidedly increased by the addition of tartar emetic, which, however, may be omitted, and the sweet spirit of nitre be substituted, if preferred. 158. Solution of Citrate of Potassa. R. Potassae Citratis 3iij; Olei Limonis gtt. ij ; Sacchari 3ij ; Aquae destillatae f^iv. Misce. Signa. — A tablespoonful to be taken every two hours. This preparation is a good substitute for the preceding, and is in several respects to be preferred. Spirit of nitre may be added when indicated. 159. Effervescing Draught. R. Potassae Carbonatis 3ij; Aquae destillatae f§iv. Solve. R. Succi Limonis recentis, Aquae destillatae, aa f^ij. Misce. Signa. — Mix two tablespoonfuls of the lemonade with one of the alkaline solution, and let the mixture be drunk while effervescing. To be repeated every two hours. This preparation differs from the neutral mixture more in the mode of exhibition than in any other important particular. It is of great value when irritability of the stomach precludes the use of ordinary diaphoretics. 82 DIAPHORETICS. 160. Mixture of Spirit of Minder er us and Antimonial Wine. B. Liquoris Ammonia Acetatis f^ij ; Aquas Cinnamomi f ^j ; Vini Antimonii f 5j ; Aquas destillatas f|ij. Fiat mistura. Signa. A tablespoonful every two or three hours. The excellent diaphoretic known as the spirit of Minde- rerus, appears to have been first used by Boerhaave, in 1732. With us it is generally prescribed in combination, as in the preceding or the following form. 161. Spirit of Minder erus, Sweet Spirit of Nitre, etc. B. Liquoris Ammonias Acetatis fHvj; Syrupi Limonis f^ij ; Vini Antimonii fSjss; Spiritus iEtheris Mtrosi f3ij; Tincturas Opii gtt. xlv. Fiat mistura. Signa. — Take a tablespoohful every two hours. Eberle. [162. Mixture of Morphia and Nitre, etc.'] B. Morphia Acetatis gr. j ; Spiritus ^Etheris Mtrosi f 3ss ; Syrupi Limonis f §ijss ; Liquoris Ammonias Acetatis fliij. Misce. Signa. Give a tablespoonful every two hours. As a diaphoretic in fevers, attended with pain or nervous irritability. 163. Sweet Spirit of Nitre and Antimonial Wine. B. Spiritus iEtheris Nitrosi f 3j ; Vini Antimonii f3ij. Misce. Signa. — A teaspoonful may be taken every hour or two hours, in barley-water, during the hot stage of intermittent and other fevers. DIAPHOEETICS. 83 164. Sweet Spirit of Nitre with Antimonial Wine and Laudanum. B. Tincturas Opii gtt. xxv; Spiritus JEtheris Nitrosi f 3j; Vini Antimonii gtt. xx; Aquas destillatas f^ss. Fiat mistura. Signa. — To be given at once, and the dose to be repeated every three hours. Dr. Chapman observes, in his Therapeutics, that " this com- bination very frequently acts as a diuretic in dropsy, and has more than once, within my knowledge, removed the effusion in this disease, under circumstances the least to be expected." 165. Mixture of Guaiacum, Saltpetre, etc. R. Pulveris Gruaiaci Resinas 3ij; Potassas Nitratis 5jss; Antimonii et Potassas Tartratis gr. j ; Pulveris Acacias, Pulveris Extracti Grlycyrrhizas, aa 3j ; Aquas destillatas f^viij. Fiat mistura. Signa. — A tablespoonful three or four times a day. This preparation, if made without the liquorice, is disposed to turn green, which gives it an unpleasant appearance, and sometimes induces the patient to refrain from it until the phy- sician arrives. It is employed principally in rheumatic cases. B. Ellis. 166. Mixture of Nitrate of Potassa. R. Decocti Hordei Oj; Potassas Nitratis 3ij ; Succi Limonis flj. Fiat potus. To be used warm as a common drink in doses of a wine- glassful. Administered in this way, saltpetre proves an excellent diaphoretic ; but if given in cold infusion its action is chiefly manifested on the kidneys. 84 DIAPHORETICS. 167. Mixture of Tolu with Wine of Antimony. R. Tincturae Tolutanas f3v; Pulveris Acaciae, Sacchari, aa 3j ; yini Antimonii f 3j ; Aquas Cinnamomi f^ij. Fiat mistura. Signa. — A tablespoonful three or four times a day. This is a stimulating diaphoretic, and will be found ser- viceable in pectoral diseases accompanied with an excessive mucous discharge depending on debility of the bronchial membrane. 168. Mixture of Gelsemium. R. Extracti Gelsemii Fluidi (Thayer), fjj; Syrupi Limonis f 3ij ; Aquae f3xiij. Misce. Signa. — Give a teaspoonful every two hours. The yellow jessamine (Gelsemium semper vir ens) has a de- pressing and sedative influence upon the nervous centres, and it diminishes the force and frequency of the heart's action. It has been employed by practitioners in various parts of the United States with benefit in febrile diseases and rheumatism. In full doses it causes vertigo and impaired vision. 169. Mixture of Aconite and Wine of Colchicum. R. Extracti Aconiti Alcoholici gr. xij ; Syrupi f 3j ; Yini Colchici Seminis f^ss. Fiat mistura. Signa. — Take fifteen drops every three hours. Used in acute and chronic rheumatism, gradually increasing the dose. Weber. 170. Mixture of Aconite and Spirit of Mindererus. R. TincturaB Aconiti Kadicis nixxx; Liquoris Ammonias Acetatis f^ij ; Syrupi Limonis f^ss. Misce. Signa. — Give a dessert-spoonful every three hours. DIAPHORETICS. 85 Employed beneficially in acute rheumatism and pleurisy. In the latter disease, aconite often relieves the peculiar lanci- nating pain in a surprising manuer. Its action should be care- fully watched. R. P. Thomas. 171. Mixture of Aconite and Veratrum Viride. R. Tincturae Aconiti Folii f 5v ; Extracti Veratri Yiridis Eluidi f3j. Misce. Signa. — Give twelve drops every two hours. Under the combined influence of aconite and veratrum vi- ride, the force and frequency of the pulse in fevers or inflam- mations can be reduced with safety and rapidity. It is neces- sary, however, to watch the effects of these remedies. Infusions. 172. Infusion of Boneset. R. Eupatorii Ij ; Aquas bullientis Oj. Macera per horam dimidiam in vase leviter clauso et cola. Signa. — Take a wineglassful every hour, till perspiration is freely induced. The infusion must be taken as hot as it can be drunk ; otherwise it may produce vomiting. Used in colds, influenza, and intermittent fever. 173. Infusion of Pleurisy Root. R. Radicis Asclepiadis, contritae 3j ; Aquas bullientis Ojss. Fiat infusum. Signa. — A teacupful to be taken warm, as frequently as the stomach will bear it. 1ST. Chapman. Professor Chapman observes of this plant : "Asa diapho- retic, I think it is distinguished by great certainty and per- manency of operation, and has this estimable property, that it produces its effects without increasing much the force of the circulation, raising the temperature of the surface, or creating inquietude and restlessness." — Therapeutics^ vol. i. p. 347. 86 DIAPHOKETICS. Sub-Class II.— ALTERATIVE DIAPHORETICS. Pills. 174. Pills of Cinnabar and Serpentaria. R. Hydrargyri Sulphureti Rubri, Pulveris Serpentarias, aa 3ss ; Syrupi q. s. Piant pilulse xij. Signa. — Two of these to be taken three times a day. They are alterative as well as diaphoretic, and are useful in herpetic and other obstinate cutaneous complaints. 175. Plummets Pills. R. Hydrargyri Chloridi Mitis, Antimonii Sulphurati, aa 5ss ; Pulveris Gruaiaci Resinas 5j ; Syrupi fusci q. s. ut nant pilulae lx. Signa. — Three pills to be taken night and morning. These pills were recommended by Professor Plummer, in leprosy, secondary syphilis affecting the skin, gleets, old ulcers, etc. etc. The decoction of guaiacum generally accom- panies their use. Decoctions. 176. Decoction of Burdock. R. Radicis Lappae §iij; Aquae Oiij. Coque ad Oij, et cola. Signa. — A teacupful may be taken five or six times a day. Used in syphilis, scurvy, arthritic affections, and rheuma- tism. 177. Decoction of Mezereon. R. Mezerei 3yj ; Aquae Oyj; Coque ad colaturae Oiv. Sub finem coctionis, adde — Extracti Glycyrrhizae ij, et cola. Signa. — Give a wineglassful several times daily. DIAPHORETICS. 87 Given in scrofula complicated with syphilis, and in various skin diseases. 178. Compound Decoction of Sarsaparilla. R. Sarsaparillse contritae §iij; Mezerei concisi 3ij 5 Aquae Oiij. Coque ad colaturae Oij. Sub finem coctionis, adde — Extracti Glycyrrhizae 3ss. Signa. — A teacupful four times daily. This preparation or its equivalent, the "Decoctum Sarsa- parillae Compositum" of the Pharmacopoeia, has long been celebrated in the secondary forms of syphilis, and the diseases produced by the improper exhibition of mercury. It is also much employed in rheumatism and chronic skin diseases. SWEDIAUR. Mixtures. 179. Mixture of Muriate of Baryta and Iron. R. Barii Chloridi 3ss; Aquae Menthae Piperitae f^ijss; Tincturae Ferri Chloridi f^ss; Syrupi Aurantii Corticis flj. Fiat mistura. Signa. — Take a teaspoonful every three hours. Used in obstinate scrofulous diseases. Each dose contains about one grain of the chloride of barium, and seventeen drops of the muriated tincture of iron. This corresponds in strength with a prescription by Fischer. 180. Mixture of Buchu and Iodide of Potassium. R. Infusi Buchu f^viij; Liquoris Potassae f 3 j ; Pota'ssii Iodidi Jss ; Spiritus iEtheris Mtrosi f 3iij. Fiat mistura. Signa. — Take two tablespoonfuls three times a day. Used in chronic and syphilitic rheumatism. S. Weight. «8 DIAPHORETICS. 181. Sarsaparilla Beer. R. Sarsaparillse contusae ft>ij ; Pulveris Guaiaci Corticis iviij ; Gruaiaci Ligni concisi, Anisi, Kadicis Glycyrrkizee contusae, aa oiv; Mezerei 3j ; Syrupi fusci Oij ; Caryophylli contusi iss ; Aquae bullientis, Congios iv. Mix these ingredients, and agitate the vessel thrice a day. "When a fermentation has "well begun it is fit for use, and may be taken in the dose of a small tumblerful twice or thrice a day. " This is the Spanish recipe for the Jarave, or diet drink, somewhat modified. If intended for old and obstinate com- plaints, as leprous affections, elephantiasis, various anomalous ulcerations and foul disorders of the skin, there ijaay be added to the jug, after fermentation has well begun, tartrate of anti- mony twelve grains, corrosive sublimate eight or ten grains, muriate of ammonia one drachm, dissolved previously in a little water. These remedies greatly increase the alterative powers of the vegetable, infusion, and so effectually prevent its decomposition that it may be kept for a long time unal- tered, even in a hot climate.'''' — See Hancock on Sarsaparilla. Journal of the Philadelphia College of Pharmacy, vol. i. No. 4. CLASS YII EXPEOTOEA5TS. Duking the administration of Expectorants the patient should be kept warm, and, if the complaint be violent, in bed. The dose of all the Expectorants should be repeated sufficiently often to allay the irritation as much as possible; for it is obvi- ous that the act of coughing increases that very irritation which originally gave rise to it. Powders, Pills, and Lozenges. 182. Povjders of Myrrh, Ipecacuanha, etc. R. Pulveris Myrrhse gr. xij ; Pulveris Ipecacuanhas gr. yj ; Potassse Nitratis 3ss. Misce, et divide in partes iv. Signa. — One to be taken every fourth hour. A stimulating expectorant used in chronic bronchitis, and the catarrh of elderly persons. — Paeis's Pharmacologia. 183. Powders of Nitrate of Potassa, Calomel, Opium, etc. R. Potass93 Mtratis gr. xxx ; Hydrargyri Chloridi Mitis, Pulveris Opii, Pulveris Ipecacuanhse, aa gr. iij. Misce, et divide in chartulas vj. Signa. — One every three hours in syrup or molasses. All powders containing calomel, or other metallic prepa- rations, should be given in syrup, as they sink when water is employed as the vehicle. Used in acute bronchitis. 90 EXPECTORANTS. 184. Pills of Sulphate of Zinc and Myrrh. R. Zinci Sulphatis gr. x; Pulveris Myrrhas 3jss; Confectionis Kosas q. s. ut fiant pilulae xx. This prescription is taken from the Pharmacologia of Dr. Paris, who recommends two of the pills to be taken twice a day. It is principally used in pertussis ; but a more efficient direc- tion would be to reduce the myrrh to a drachm, on account of the size of the pills, and to give a pill every two hours. Dr. Paris remarks, that the principal nostrums for hooping-cough are formed either of opium or sulphate of zinc, or a combina- tion of the two. 185. Pills of Hemlock and Dover's Powder. R. Extracti Conii, Pulveris Ipecacuanha Compositi, aa gr. x. Misce, et fiant pilulse v. Signa. — Two may be taken at bedtime. In pulmonary irritation, attended with rheumatic and other local pains. 186. Pills of Tartar Emetic and Opium. R. Antimonii et Potassse Tartratis, Pulveris Opii, aa gr. jss ; Pulveris Tragacanthse gr. x ; Confectionis Eosse q. s. ut fiant pilulse xxv. Signa. — Two to be taken night and morning. In chronic pulmonary catarrh. Dr. Pariset. [187. Pills of Antimony, Dover's Powder, and Calomel] R. Hydrargyri Chloridi Mitis gr. iij ; Pulveris Antimonialis, Tyson (formula 148) gr. xij ; Pulveris Ipecacuanhas Compositi gr. xxiv ; Syrupi q. s. Misce, et divide in pilulas xij. Signa. — Give one pill every two hours. A very efficient expectorant and anodyne in the early stages of pneumonia, pleurisy, or acute bronchitis. EXPECTOKANTS. 91 188. Pills of Squill, Ammoniac, and Hemlock. R.' Pulveris Scillse, Extracti Conii, aa 3ss ; Ammoniaci 5j- Fiat massa, et divide in pilulas xxx. Signa. — One pill every four hours. Like the officinal " Pilulee Scillse Composita3," this is an efficient expectorant combination, which may be prescribed with great benefit in chronic bronchitis, catarrh, and asthma. 189. Pills of Calomel, Squill, Ammoniac, etc. R. Hydrargyri Chloridi Mitis gr. iij ; Scillse recentis, Ammoniaci, aa 9j ; Pulveris Ipecacuanhas Compositi 5ss ; Confectionis Kosae q. s. ut flat massa, in pilulas xxx divi- denda. Signa. — One four times a day. This formula is recommended by the celebrated Dr. Latham, of London, for the relief of troublesome cough. In this country it will generally be necessary to substitute dried squill in half of the quantity, owing to the difficulty of obtaining the fresh article. 190. Pills of Calomel, Squill, Tartar Emetic, etc. R. Hydrargyri Chloridi Mitis gr. xxiv ; Pulveris Scillge 3ss ; Antimonii et Potassse Tartratis gr. vj ; Pulveris Opii gr. xviij ; Syrupi q. s. Fiant pilulse xxiv. Signa. — One every night. In chronic catarrhal affections. 191. Pills of Tar and Gentian. R. Picis liquidae 3j ; Pulveris Glentianae q. s. ut fiat massa. Fiant pilulas xxx. Signa. — Take a pill morning, noon, and night. Tar is a mild, stimulant expectorant ; and is often employed, in different forms, in chronic bronchial affections and consump- tion. 92 EXPECTORANTS. 192. Pills of Myrrh, Squill, and Henbane. R. Myrrhae 3j ; Pulveris Scillae, Extracti Hyoscyami, aa 3ss ; Aquae destillataa q. s. ut fiat massa in pilulas xxx divi- denda. Signa. — Two to be taken night and morning. These pills are recommended by Dr. Paris in phthisis and catarrh attended with great debility of the pulmonary organs. 193. Wistarh Cough Lozenges. R. Pulveris Acacias, Extracti Grlycyrrhizas, Sacchari, aa 3ij ; Pulveris Opii gr. vj ; Olei Anisi gtt. iv. Misce et aclcle — ■ Aquae destillatae q. s. ut fiant trochisci lx. Signa. — One of these may be dissolved in the mouth three or four times a day. These lozenges, which were originally prescribed by the late Prof. 0. Wistar, have long been highly esteemed for their demulcent and anodyne properties, and have been much em- ployed both in general and domestic practice for the relief of cough. Mr. Edward Parrish recommends the substitution of sulphate of morphia, in equivalent quantity, for the opium. He also directs the lozenges when dry to be varnished with tincture of Tolu. These changes improve their flavor without impairing their efficiency. 194. Spittcfs Lozenges. R. Pulveris Cubebae 3ij ; Balsami Peruviani gr. vj ; Syrupi Tolutani f *j ; Extracti Glycyrrhizae 5J ; Acaciae q. s. ut fiat massa, in trochiscos singulos grana x pendentes, dividenda. These lozenges are celebrated for the relief they afford in hoarseness and coughs. Spitta. EXPECTORANTS. 93 195. Jackson } s Pectoral Lozenges. R. Pulveris Ipecacuanhas gr. x; Antimonii Sulphurati gr. v; Morphias Muriatis gr. vj ; Pulveris Acacias, Sacchari, Pulveris Extracti Glycyrrhizas, aa 5xj ; Olei Sassafras gtt. iv ; Tinctures Tolutanas f3iv; Syrupi q. s. Fiat massa, in trochiscos cc dividenda. Each lozenge, weighing ten grains, contains of ipecacuanha gr. ^o ; of the precipitated sulphuret gr. ^ ; and of the muriate of morphia gr. ^. Signa. — One of these to be dissolved in the mouth, when the cough is troublesome. S. Jackson". Syrups. As cough medicines have to be repeated at short intervals for the purpose of maintaining a gentle impression upon the pulmonary organs, it is desirable to administer them in the most agreeable form. Hence they are generally prescribed as syrups, the sugar in which serves the double purpose of covering the taste and acting as a demulcent to the mucous membrane. The officinal syrups of garlic, squill, and seneka are given in a dose of a teaspoonful each. They are all slightly stimu- lant, and in large doses nauseant. The syrup of wild cherry bark is tonic, astringent, and sedative. Its dose is a tablespoonful. The syrups of gum Arabic, of almonds (orgeat), and of Tolu, are used chiefly as demulcents and flavoring agents. The compound syrup of squill (Coxe's hive syrup) exhibits the anomalous association of a sedative (tartar emetic) with two valuable stimulant expectorants — squill and seneka. It is more often employed as an emetic for croup, than as an ordinary expectorant. 196. Syrup of Squill, Seneka, and Ipecacuanha. R. Syrupi Scillse, Syrupi Senegas, Syrupi Ipecacuanhas, aa f§j. Misce. Signa. — A teaspoonful every three hours. 94 EXPECTORANTS. This is a favorite combination with many physicians, as it combines the expectorant qualities of the squill and seneka, with the relaxing effect of the ipecacuanha. Morton. 197. Syrup of Squill and Ipecacuanha, with Paregoric. R. Syrupi Scillas, Syrupi Ipecacuanhas, Tincturse Opii . Camphor atae, aa f^j. Misce. Signa. — A teaspoonful every three hours. This preparation is more relaxing and soothing than the last, and may be given beneficially when the patient has a troublesome cough, with deficient expectoration. 198. Syrup of Ipecacuanha, American Hellebore, etc. R. Syrupi Ipecacuanhas, Spiritus ^Etheris Nitrosi, aa f 3ss ; Tincturse Yeratri Viridis n^xv. Misce. Signa. — Fifteen drops every three hours. This formula was employed in a large number of cases of pneumonic and bronchial diseases in children, and found to be a most efficient sedative and expectorant. The above dose may be given to a child one or two years old. The pulse must always be watched during the administration of Ameri- can hellebore. B. F. Schneck. 199. Syrup of Assafetida. R. Assafoetidas Ij; Aqua bullientis Oj ; Sacchari Bbij. Triturate the assafetida in a mortar with a portion of the boil- ing water, until a uniform paste is formed; then gradually add the remainder of the water, strain, and add the sugar, applying a gentle heat to dissolve it. Dose, a teaspoonful every three hours, for a child five years old. Each fluidounce contains fifteen grains of assafetida. This preparation will keep a month in the hottest weather. Its taste is less nauseous than the milk of assafetida, and, alto- gether, it is one of the very best modes of administering the fetid drug to children, in hooping- con gh, I am acquainted with. E. Peltz. EXPECTOKANTS. 95 200. Another Form. B. Assafcetidas oSs ; Magnesias Carbonatis 3yj. Tere simnl et adde gradatim — Aquas bullientis f 3x. Cola et adde — Saccbari ^xv. Solve cum leni calore. Signa. — Dose, a teaspoonful. As tbis preparation should measure a pint, each fluidounce will contain fifteen grains of the fetid drug. J. A. Heintzelman. 201. Syrup of Wild Cherry Bark and Prussia Acid. B. Syrupi Pruni Virginianas f siij ; Syrupi Tolutani f sj ; Acidi Hydrocyanici diluti "Ixvj. Misce. Signa. — Dose, a dessert-spoonful every three hours. When well prepared, this syrup represents the tonic and sedative properties of the wild cherry, which render this bark so peculiarly applicable to the treatment of phthisis. The addition of the prussic acid renders the preparation more sedative. E. P. Thomas. 202. Syrup of Garlic and Tolu with Paregoric. B. Syrupi Allii, Syrupi Tolutani, aa f Jj ; Tinctures Opii Camphoratae f3ij. Misce. Signa. — Dose, half a teaspoonful every three hours for a child five years old. In general properties, garlic bears a close resemblance to squill. This combination may be given with great advantage in the advanced stages of catarrhal complaints of children. 203. Jackson } s Pectoral Syrup. B. Sassafras Medullas 3j ; Acacias 3j ; Aquas Oj. Macera per boras duodecim, dein adde — Sacchari ^xxj. Et solve sine calore, cola, et adde — Morpbias Muriatis gr. viij. Signa. — Take a teaspoonful every three hours, 96 EXPECTOKANTS. It is intended that this preparation, when completed, shall measure two pints, and if it does not, the operator is to add the complement of water, so that each fluidounce shall con- tain one-fourth of a grain of the muriate of morphia. It is much employed in Philadelphia. Samuel Jackson. 204. Another Form. R. Syrupi Acacia? fliv; Morphias Muriatis gr. j ; Olei Sassafras gtt. j. Misce. Signa. — Dose, a teaspoonful every three hours. This is a convenient form for the extemporaneous prepara- tion of Jackson's Pectoral Syrup. 205. Substitute for Aubergier 1 s Syrup. R. Syrupi Lactucarii f^ij; Syrupi Acacias f 3jss ; Syrupi Aurantii Florum f^ss. Misce. Signa. — A teaspoonful every three hours. This is a mild anodyne syrup, and is useful in bronchitis, catarrhus senilis, and consumption. Mixtures. 206. Mixture of Syrup of Squill, etc. R. Syrupi Scillas f .3 ss ; Tincturas Opii Camphoratas f 3ij ; Yini Antimonii f 3j ; Aquas destillatas fliij. Misce. Signa. — A teaspoonful every three hours. This is more particularly designed for children. 207. Mixture of Squill, Morphia, and Prussic Acid, R. Morphias Muriatis gr. j ; Acidi Muriatici diluti "iv ; Acidi Hydrocyanici diluti tt^xxx; Syrupi Scillas, Aquas, aa f 3J. Misce. Signa. — Dose, a teaspoonful when the cough is troublesome. Used in phthisis. T. Thompson. EXPECTORANTS. 97 208. Mixture of Seneka, Squill, Tartar Emetic, etc. R. Decocti Senegse f liv ; Syrupi Ipecacuanhas f §j ; Syrupi Scillas f ^ss ; Antimonii et Potassae Tartratis gr. j. Fiat mistura. Signa. — A teaspoonful for children of two years of age and upwards. In croup. 209. Mixture of Seneka, Ammoniac, and Tolu. R. Decocti Senegae f^vj ; Syrupi Tolutani f£j ; Ammoniaci 5ss. Misce secundum artem. Signa. — A tablespoonful every two hours. In catarrh. 210. Mixture of Ammoniac and Squill R. Ammoniaci, Extracti Grlycyrrhizaa, aa 3ss ; Aceti Scillae fsss ; Aquas Fceniculi f^vss. Fiat mistura. Signa. — A tablespoonful every two hours. This is a stimulant preparation, useful in chronic bronchitis and senile catarrh. 211. Mixture of Hemlock, Paregoric, and Tolu. R. Extracti Conii Fluidi fjij ; Tincturae Opii Camphoratse, Syrupi Tolutani, aa f oSs ; Aquas Kosas f siv. Misce. Signa. — Thirty drops may be given once in four hours to a child a year old, watching the effect. Dr. Pearson, in his work on pertussis, recommends the above as a valuable formula. y» EXPECTORANTS. 212. Almond Emulsion, Ipecacuanha, etc. B. Misturae Amygdalas f^v ; Yini Ipecacuanhas, Tincturas Scillae, aa f 5ij ; Syrupi Tolutani f 3ss. Misce. Signa. — Take a tablespoonful whenever the cough is urgent. Used in chronic bronchitis and consumption. 213. Mixture of Sal Ammoniac, Squill, etc. B. Ammonias Muriatis sss; Pulveris Acacias 3ij ; Pulveris Extracti Grlycyrrhizas 5iij; Aquas f^vjss ; Spiritus JStheris Nitrosi f 3jss ; Aceti Scillae fS.iij. Fiat mistura. Signa. — A dessert-spoonful every two hours. A stimulating expectorant and alterative, useful in the ad- vanced stages of bronchial disease. Goeden. 214. Mixture of Naphthaline. R. Naphthalinae gr. xvj. Alcoholis q. s. ut fiat solutio. Dein adde — Syrupi f £iv. Misce. Signa. — Take a tablespoonful every two hours. This is a stimulating expectorant, useful in chronic catarrh, humoral asthma, etc. Dupasquier. 215. Mixture of Oil of Amber and Tolu. R. Olei Succini rectificati f3j ; Pulveris Acacias, Sacchari, aa ^ss; Aquas destillatas f 3iv ; Tincturae Tolutanas f 5ij. Fiat mistura secundum artem. Signa. — A tablespoonful every two or three hours. In spasmodic cough. EXPECTORANTS. 99 216. Mixture of Bloodroot, Wild Cherry Bark, etc. R. Morphias Acetatis gr. iij ; Tincture Sanguinarias f 3ij ; Vini Antimonii, Yini Ipecacuanhas, aa f3iij ; Syrupi Pruni Virginianas f oiij. Misce. Signa. — Dose, a teaspoonful. Used in catarrhal affections, bronchitis, and influenza. J. C. Ayer. 217. Mixture of Wild Cherry , Morphia, etc. R. Morphias Acetatis gr. ij ; Acidi Acetici diluti f 5j ; Syrupi Pruni Yirginianae, Syrupi Ipecacuanhas, Syrupi Tolutani, aa f Jj. Misce. Signa. — A teaspoonful every three hours. This is an excellent combination for the treatment of catar- rhal affections and chronic bronchitis. 218. Mixture of Tartar Emetic and Laudanum. R. Antimonii et Potassas Tartratis gr. j ; Aquas destillatas f 3iij ; Tincturas Opii ntxx. Misce. Signa. — Give a teaspoonful at bedtime to a child five years old. Prescribed in hooping-cough. Sir ¥i. Watson. 219. Mixture with Bicarbonate of Soda, etc. R. Sodas Bicarbonatis gr. xij ; Yini Ipecacuanhas n\.xx ; Tincturas Opii ^iv; Syrupi, Aquas destillatas, aa f Ss§. Misce. Signa. — Give a teaspoonful every three hours. This preparation is designed for children, and is chiefly used in hooping-cough. 100 EXPECTORANTS. [220. Mixture of Bromide of Ammonium. ~\ B. Ammonii Bromidi 9ij ; Syrupi Aurantii f Sjss. Misce. Signa. — Give a teaspoonful every four hours. In hooping-cough, for a child. 221. Cochinea I Mixture. R. Potassae Carbonatis 3j ; Pulveris Cocci 9ss ; Sacchari 3j ; Aquae destillatae f^iv. Fiat solutio. Signa. — Dose for children, a teaspoonful every two or three hours. An effectual remedy in hooping-cough. N. Chapman. 222. Mixture of Lobelia, Squill, and Belladonna. B. Tincturae Lobeliae, Syrupi Scillae, aa f ,lj ; Extracti Belladonnae gr. iv. Misce. Signa. — Dose, thirty drops four times daily. This combination has afforded great relief in hooping-cough, especially during the second stage. The dose specified is for a child five or six jes^rs old. W. Herbst. 223. Mixture of Assnfeiida, etc. R . Assafoetidae 3j ; Aquae foiv. Fiat mistura, et adde— Tincturae Tolutanae f Iss ; Tincturae Opii n^xl. Signa. — A teaspoonful to a child every two hours, and a dessert-spoonful (or more) as frequently to an adult. This preparation is of great value in pertussis and other spasmodic diseases of the chest, S. G. Morton. EXPECTORANTS. 101 224. Mixture of Bloodroot, Naphtha, etc. R. Tincturae Sanguinarias f ,*j ; Tincturae Opii Camphoratas f 5ij ; Spiritus Pyroxilici, Dub. f 3ss ; Potassas Nitratis 3ss ; Aquas foj. Misce. Signa. — A teaspoonful every two hours. This is a modification of a formula of Dr. E. H. Sholl, who speaks in the most favorable terms of the value of bloodroot in pneumonia, croup, hooping-cough, etc. It is one of the most powerful medicinal agents. It is violently emetic in large doses, but in the quantity recommended is said to pro- duce diaphoresis and effects analogous to those of digitalis. 225. Mixture of Wood Naphtha and Morphia. R. Spiritus Pyroxilici, Dub. f3ij ; Liquoris Morphias Muriatis, Ed. f 3iij ; Aquas destillatae f 3v, f3iij- Fiat mistura. Signa. — Dose, a tablespoonful three times daily. Prescribed in bronchitis with profuse expectoration, and in phthisis. Laycock. 226. Mixture of Ammoniac, Squill, and Paregoric. R. Ammoniaci 3j ; Aquas destillatas f liv. Fiat mistura, et adde — Syrupi Scillas f ,?ij ; Tincturae Opii Camphoratas f 3ss. Misce. Signa. — A tablespoonful may be given every two hours. A stimulating expectorant, useful in chronic bronchitis, senile catarrh, etc. 227. Mixture of Assafetida and Acetate of Ammonia. R. Assafoetidas 3ss ; Liquoris Ammonias Acetatis, Aquas Menthas Viridis, aa f sij. Fiat mistura. Signa. — A teaspoonful to children, and a tablespoonful to adults, in coughs. 102 EXPECTORANTS. This simple solution of assafetida was frequently employed by the elder physicians, and was found to answer every pur- pose of more complicated prescriptions. 228. Mixture of Copaiba and Balsam of Tolu. R. Copaibas, Balsami Tolutani, Pulveris Acaciae, aa Iss; Aquae destillatae f.lvj; Acidi Sulphurici Aromatici n^xx. Fiat mistura secundum artem. Signa. — Dose, a tablespoonful. In chronic catarrh and hooping-cough. When there is hectic excitement, digitalis may be added. 229. Mixture of Balsam of Peru. R. Balsami Peruviani ^ss ; Pulveris Acaciae, Sacchari, aa 3ij ; Aquae Cinnamomi, Aquae destillatae, aa f^iij. Misce. Signa. — A tablespoonful four times a day. The different balsams were at one time almost proscribed from the class of expectorants, on account of their stimulating qualities ; but they are now much employed in diseases of the pulmonary mucous membrane. 230. Tar Water. R. Picis liquidae Oij ; Aquae Cong. j. Mix and stir them together with a wooden rod for an hour ; then let the tar subside, strain the water, and keep it in well- corked bottles. — A pint, or even two pints, may be taken daily in divided doses ; but in cases of bronchial irritation, the dose must be greatly diminished. 231. Mixture of Oil of Tar. R. Olei Picis liquidae f3ij ; Magnesiae Carbonatis 9ij. Tere simul, et adde gradatim — • Aquae f^xiv. Cola et adde — Syrupi f ^ij. Misce. Signa. — A wineglassful to be taken four times daily. EXPECTORANTS. 103 This is probably the most effectual of the tar preparations, and may be resorted to beneficially in cases of senile catarrh, chronic bronchitis, and consumption. B. J. Ceew. 232. Mixture of Gum Ammoniac and Nitric Acid. R. Ammoniaci Dijss ; Acidi Nitrici diluti f 3ij ; Aquae foviij. Misce. Signa. — A tablespoonful to be taken four times a day. This preparation is strongly recommended •in protracted catarrh and phthisis pulmonalis, by Dr. J. Stuart, author of a treatise on Colds. 233. Spermaceti Mixture. R. Cetacei 5ij ; Sacchari 3iij ; Yitellum unius ovi. Tere sirnul, et adde gradatim — Tincturse Opii Camphoratae f.Iss; Aquae foviij. Misce. Signa. — A tablespoonful for a dose, four or five times a day. Used in catarrh. 234. Syrup of Tolu with Belladonna, etc. R. Tincturae Belladonnas, Vini Ipecacuanhas, aa f 3ij ; Syrupi Senegas f 3ss ; Syrupi Tolutani f^iij. Misce. Signa. — Take a teaspoonful three or four times a day, freely using gum- water acidulated with lemon-juice. In coughs. 235. Flaxseed Tea. R. Lini §j ; Kadicis Grlycyrrhizas contusas ^ss ; Aquas bullientis Oj. Macera per horas duas in vase leviter clauso, cola et adde — Succi Limonis f 3j. Misce. This may be given as a common drink in catarrh. 104 EXPECTORANTS. 236. Decoction of Iceland Moss. B. Cetrarias lj ; Aquas Ojss. Coque ad Oj, et cola. This article once acquired great celebrity in coughs ; but was overrated, and lost its reputation. It contains a bitter principle, which is sometimes an advantage in dyspepsia and phthisis. If freed from this, by macerating before boiling, and throwing the first liquor away, as is sometimes done, the preparation is v reduced to a mere demulcent, and has no ad- vantages over other members of that class. 237. Mixture of Prussic Acid. R. Acacia *ss; Aquas f^vijss. Fiat mistura, et adde — Syrupi Tolutani f Iss ; Acidi Hydrocyanici diluti, gtt. xij. Fiat mistura. Signa. — Take a tablespoonful every three hours. Used to allay cough in consumption. This is "a medium dose," which I prefer in commencing the use of so powerful a medicine. — S. Gr. Morton, Illustra- tions of Pulmonary Consumption, p. 132. We cannot enjoin too much caution in the use of all the preparations of prussic acid, some of which are extremely variable in themselves, and all produce very unequal effects on different constitutions. It is questionable whether the practice of medicine has gained anything by their adoption into the Materia Medica. 238. Mixture of Cyanide of Potassium. R. Potassii Oyanidi gr. j ; Aquas destillatas fgiijss; Syrupi Limonis f 3ss. Misce. Signa. — Dose, a tablespoonful every two hours. In this formula by Mr. Donavan, of Dublin, the lemon syrup is added for the purpose of securing the formation of hydrocyanic acid, by its chemical action on the cyanide. Em- ployed to check vomiting, and allay cough ; and, in much smaller doses, in the hooping-cough of children. EXPECTORANTS. 105 339. Mixture of Lobelia and Prussic Acid. R. Tincturas Lobelias f3ss ; Acidi Hydrocyanici diluti gtt. j. Misce. Signa. — To be taken at a dose, three or four times a day. Highly serviceable in asthma and (in very small doses) in hooping-cough. Livezey. 240. Mixture of Gum Ammoniac, Castor, etc. R. Misturas Ammoniaci f aiij ; Tincturas Castorei f 5ss ; Syrupi Tolutani f^ss ; Tincturas Opii «lxxx ; Aquae Cinnamomi f3j. Fiat mistura. Signa. — A small tablespoonful every four hours, in trouble- some cough. C. D. Meigs. [241. Mixture of Morphia, Turpentine, etc.'] R. Morphias Acetatis gr. j ; Olei Terebinthinas gtt. cxx ; Spiritus iEtheris Nitrosi f oSs ; Acacias pulveris Sss ; Syrupi Pruni Virgin ianss f Ij ; Liquoris Ammonias Acetatis f siv. Misce secundum artem. Signa. — Give a tablespoonful every two hours. An effectual stimulating expectorant in pneumonia. 242. Mixture of Morphia, Squill, and Tolu. R. Syrupi Scillas f ,5 jss; Syrupi Tolutani f^ss; Morphias Acetatis gr. j. Misce. Signa. — A teaspoonful may be taken every three hours. In phthisis and other diseases attended with cough. 243. Mixture of Tolu, Morphia, and Tartar Emetic. R. Mucilaginis Acacias Oj ; Syrupi Tolutani, fsij ; Morphias Sulphatis, gr. ij ; Antimonii et Potassas Tartratis, gr. ij. Misce. Signa. — A tablespoonful to be given every two hours. S. G. Morton on Consumption, p. 123. 106 EXPECTORANTS. 244. Glycerine with Morphia and Iodide of Iron. B. Morphias Sulphatis gr. iij ; Syrupi Ferri Iodidi f 5ss ; Glycerinas f^iijss. Misce. Signa. — A teaspoonful every four hours. This is particularly serviceable in the advanced stages of consumption, to arrest the emaciation, and allay the cough. N. S. Davis. 245. Syrup of the Hypophosphites of Lime, Soda, etc. R. Calcis Hypophosphitis 5vj ; Sodas Hypophosphitis, Potassas Hypophosphitis, aa 3ij ; Aquas ferventis fS'x. Solve, cola et adde — Sacchari ^xiv. Solve leni calore, cola et adde — Aquas Aurantii Florum f.5ss. Misce. Signa. — Dose, a teaspoonful every three hours. Dr. Churchill has directed the attention of the profession to the value of the hypophosphites in the treatment of con- sumption. A glycerole could be readily formed by substi- tuting glycerine for a portion of the water and sugar in this formula. Each dose contains about five grains of the mixed salts. E. Parrish. 246. Infusion of Tar and Hops. B. Infusi Picis liquidas Oij ; Humuli 3ss. Misce, macera per horas duas, et cola. Signa. — Dose, a wineglassful morning, noon, and night. This is a useful tonic and expectorant in consumption. Inhalation. Inhalation is a means of applying remedies directly to the lungs. A good instrument for this purpose is the inhaler of Mudge; but as a substitute the common teapot may be used, or a funnel inverted over a bowl. The substances usually EXPECTORANTS, 107 selected for inhalation are, the steam of warm water ; the steam of vinegar, produced by pouring it into boiling water ; and various other articles next to be enume- rated. An excellent inhaler may be made by taking an ordinary wide- mouthed bottle, such as contains sulphate of quinia, for example — ■ fitting a cork accurately; then boring two holes about three- eighths of an inch in diameter, and inserting into each a tube of glass, of which one passes to the bottom of the liquid, rising only a little above the cork, the other simply passing through the cork without reaching the liquid, but upon the outside, bent into a long mouthpiece. When the medicated solution re- quires to be warmed to obtain the benefit of volatilization of its ingredients, the bottle may be set into a vessel of hot water. 247. Inhalation of Balsam of Tolu. R. Balsami Tolutani Ej ; Aquae bullientis Oj. Misce. Signa. — Inhale the vapor through an inverted funnel. 248. Inhalation of Tolu and Ether. B. Balsami Tolutani, partem j; JEtheris, partes iij. Solve. Signa, — The solution should be placed in a wide-mouthed bottle, from which the patient is to inhale freely several times a day, in chronic catarrh, aphonia, and chronic affec- tions of the chest. Koziere. 249. Ethereal Tincture of Iodine and Hemlock for Inhalation. R. Iodinii gr. viij ; Pulveris Conii gr. xvj ; ^Etheris fgij. Misce, et macera per horas viginti quatuor. Signa. — Half a teaspoonful at a time is to be breathed from a wineglass grasped in the warm hand, and repeated twice or thrice a day. If it does not affect the head, the quan- tity inhaled may be gradually increased to a teaspoonful. 108 EXPECTOBAXTS. Used Id chronic bronchitis and consumption. S. G. Mobtox. 250. Scuda.more s Iodine Mixture for Inhalation. B. Iodinii, Potassii Iodidi, aa gr. vj ; Aquae destillatae f3v, f5yj ; Alcohoiis f 5J. Misce. I usually commence with a drachm of this mixture, pro- ceeding gradually to the extent of half an ounce (rarely more), putting two-thirds the dose for the first half of the time (10, 15, or 20 minutes), and the other third for the re- mainder, always adding thirty minims of a saturated tincture of couium, with an increase, if the cough be very irritable. Occasionally, I add some saturated tincture of ipecacuanha ; and when the respiration is spasmodically affected, some ethe- real tincture of lobelia inflata. Sib C. Scuda^ioee. 251. Mixture of LugoVs Solution and Hops for Inhalation. B. Liquoris Iodinii Compositi f 3ij ; Tincturae Humuli f si v. Misce. Signa. — A tablespoonful is added to two fluidounces of hot water in an inhaler, or in a cup covered with an inverted funnel. The amount of inhalation will have to be deter- mined in each case by the sensations produced. In some instances s:reat relief is afforded, but in others a sense of suffocation may occur, if the inhalation be prolonged. 252. Inhalation of Tar. B. Picis liquidaa Ixvj ; Liquoris Potassae f^j. Misce. "The two ingredients being well mixed, should be first boiled for a few minutes in the open air, in order to disengage any impurities, and then be kept at a simmer in the room of the patient. This is effected by putting the mixture in an iron vessel, and placing the latter over a spirit-lamp, or some analogous contrivance. In this way, not only a chamber, but an entire house, is speedily pervaded by a most agreeable vapor, which, although it may at first excite some disposition to cough, both in healthy and sick persons, very soon, in a EXPECTORANTS. 109 majority of cases, allays this symptom, and with it a great proportion of the patient's distress." — Morton on Consumption. Sir A. Crichton. 253. Rosin Inhalation. The fumes of rosin were much employed by the late Dr. Joseph Parrish, of this city ; he directed it to be put on a hot shovel or coals, and allow the patient gradually to inhale them. To some persons, rosin is very agreeable, while the lungs of others cannot tolerate it. 254. Arsenical Inhalation. B. Sodas Arseniatis 3ss ; Aquas destillatae f ov. Solve. Signa. — Arsenical solution. Thirty slips of bibulous paper of a determinate size (about six inches by four inches), are dipped into the arsenical solu- tion, and are then dried and rolled into the form of cigars. Thus prepared, each cigar represents a known weight of the arseniate, about one grain. " The patient, having lighted a cigar, draws the smoke into his mouth, and, by a gentle inspiration, permits it to enter the lungs. At first, he may take four or five inspirations, thrice daily ; and, as he becomes accustomed to the impression, he increases their number. "If there be much oppression, stramonium leaves may be rolled up with the arsenicated papers." This inhalation has been of some service in consumption, but it is in old catarrhs, chronic bronchitis, and laryngeal disease, that its effects are the most striking. Trousseau. 255. Mercurial Inhalation. B. Hydrargyri Oxidi rubri 9j. Heat gradually on the point of a spatula, over a spirit-lamp, and conduct the fumes to the mouth or nostrils by means of an inverted glass funnel. Used in ozsena and syphilitic affections of the mouth or throat, as well as in chronic diseases of the air-passages. 110 EXPECTORANTS. 256. Stramonium Inhalation. ' Stramonium inhalation is particularly serviceable in asthma. The leaves, deprived of their midribs, are dried, cut, and smoked in a common tobacco pipe. Persons unaccustomed to the remedy find one pipe sufficient, while others can bear three or four in the course of a day, during a fit of the asthma. The Parisian pharmaceutists prepare anti-asthmatic cigar- ettes, by moistening the stramonium leaves with a strong in- fusion of opium. The leaves are then dried, cut, and rolled in strips of paper, and the ends are twisted. Some patients are annoyed by the copious production of smoke in the combustion of stramonium. To obviate this in- convenience, M. Dannecy, of Bordeaux, waters the leaves (previously dried and spread out) with a solution of nitrate of potassa, in the proportion of three ounces of the salt to two pounds avoirdupois of the plant. By this process the combustion is rendered more complete and less annoying, and the patient experiences additional benefit from the fumes of the saltpetre. In fact, many asthmatics have learned by practical experi : ence that no remedy affords more certain and prompt relief for their sufferings than the ignition in their chamber of slips of paper previously saturated with nitrate of potassa and dried. E. P. T. 257. Inhalation of Chlorine. Chlorine gas has also been much used by inhalation, not pure, however, but mixed or diluted with atmospheric air. Por this purpose, a little acid of any kind may be dropped gently on a mixture of chloride of lime, by which means the chlorine is gradually disengaged, and is inhaled as it rises ; or the air of a room may be pervaded with it in like manner. It has been much commended in bronchitis and the kindred affections, but it is getting into disuse from its manifest in- efficiency. [258. Inhalation of Cubebs and Carbolic Acid.'] B. Tincturas Cubebas f'sss; Acidi Carbolici liquidi gtt. xx. Misce. Signa. — Add to half pint of hot water in an inhaler, and use every three or four hours, taking full inspirations until tired. EXPECTORANTS. Ill Found to be a very efficient relief in the dry cough, and pain of phthisis. [259. Atomization of Fluids for Inhalation.] The most important improvement which has been made in the topical application of remedies to the respiratory mucous membrane is in the inhalation of atomized liquid, or liquid broken into a fine spray by means of a simple apparatus for the purpose, and diffused through the air which is drawn into the lungs. The atomizers used for this purpose are now so well known to the profession that a description of them is not necessary, and if it were desirable, the limits of this work would not warrant it. For a full description and history of this method of medication the reader is referred to the valuable little monogram upon this subject by Dr. J. M. Da Costa. From that work I would simply extract the following formulae for fluids to be used in the atomizer : — The doses given are calculated for the fluidounce of water. ( 10 to 20 grs. — In chronic catarrh of pharynx and Alum I air tubes. (_ 30 grs. — In pulmonary hemorrhage. Tannin 1 to 20 grs. — In same condition as alum. Ferri Perchloridum gr. £-ij. — Earliest stages of phthisis. Argenti Nitras gr. j-x. — In ulcerations of the pharynx and larynx (a face shield to be used always). Zinci Sulphas gr. j-vj. — In bronchial catarrh and aphonia. Sodii Chloridum gr. v-xx. — In free expectoration of phthisis. Liquor Sodse Chlorinalee f3ss-j. — In gangrene, and offensive bronchitis and phthisis. Potassse Chloras gr. x-xx. — In chronic laryngitis with dry- ness. Extractum Opii Aquosum gr. J-J. — In irritative coughs, and for general anodyne. Tincturse Opii gtt. iij-x. — In irritative coughs, and for general anodyne. Morphise Acetas gr. ^~l- — For same; large doses require caution. Extractum Conii Fluidum ttliij-viij. — Irritative cough ; asthma. Extractum Hyoscyami Fluidum ^liij-x. — Spasmodic coughs, pertussis. Tincturse Cannabis Indicse tflv-x. — Spasmodic coughs, phthisis. Liquor Iodinii Compositus n^ij-xv. — Chronic bronchitis, phthisis. 112 EXPECTORANTS. Liquor Potassse Arsenitis ™ j-xx. — Nervous asthma( Trous- seau). Aqua Picis Liquidise f 3j-ij of officinal solution. — As anti- septic. Olei Terebiniliinse fllj-ij. — In bronchorrhoea, gangrene of lungs. Liquor Ccdcis ) ordinary strength. — In diphtheria, mem- Syrupus Calcis j branous croup. Aquas Destillatx. — In haemoptysis, to be used cold. CLASS Till. EMMEIAGOGUES AND UTEEISE EEMEDIES. Emmenagogues are those medicines which promote the menstrual discharge, or restore it when entirely suppressed. Although by some authors the specific action of these medi- cines on the uterus has been questioned, if not denied; yet by others, of equal authorhVy, it has been fully acknow- ledged. It must, however, be observed, that amenorrhoea occurs under opposite states of the system ; and when general de- bility appears to be the cause of the local disease, it may be advisable to accompany the emmenagogue with an active course of tonics. While, on the contrary, if the obstruction be the effect of a plethoric habit, bleeding, cathartics, etc., are essential preliminaries to the successful exhibition of a specific remedy. Powders and Pills. 260. Powder of Aloes, Canella, and Serpentaria. R. Pulveris Aloes Barbadensis £j ; Pulveris Canellse gr. xviij ; Pulveris Serpentarias gr. xij. Misce, et divide in pulveres yj. Signa. — One every night, at bedtime, in syrup. This compound, which is one form of the Mera picra of the shops, forms a very good purgative, and is usually employed as an emmenagogue. 114 UTERINE REMEDIES. 261. Powder of Savin, Sulphate of Potassa, etc. R. Pulveris Sabinas, Pulveris Zingiberis, aa 3j ; Potassae Sulphatis 3ij- Fiant pulveres vj. Signa. — One to be taken thrice a day. Savin is an excellent stimulant emmenagogue, and when administered just before the menstrual period, often aids in producing the flow. 262. Powder of Savin and Cantharides. R. Pulveris Sabinae 3j ; Pulveris Cantharidis gr. ij. Misce, et divide in pulveres iv. Signa. — One to be taken every night on going to bed, watch- ing its effects. Used in amenorrhoea. 263. Powder of Savin and Ergot. R. Pulveris Ergots, Pulveris Sabinae, aa 9ij. Misce, et divide in chartulas iv. Signa. — One may be taken morning and night. This is a good combination for aiding in the restoration of the menstrual discharge. 264. Powder of Savin, Borax, and Ginger. R. Pulveris Sabinae, Pulveris Zingiberis, aa gr. vij ; Sodas Boratis gr. xv. Fiat pulvis. This powder is to be taken twice a day, in amenorrhoea with a languid pulse. Thomson. 265. Compound Pills of Iron and Myrrh. R. Myrrhae 3ij ; Potassae Carbonatis 3j. Tere simul, dein adde — Ferri Sulphatis, Sacchari, aa 3j- Fiat massa, et divide in pilulas lxxx. Two or three pills are given three times a day in amenor- rhoea and chlorosis. Hulse. UTERINE REMEDIES. 115 266. Hooper's Pills. R. Ferri Sulphatis exsiccatae 3j ; Pulveris Jalapaa gr. xv ; Pulveris Aloes et Canellaa 3j ; Myrrhae gr. viij ; Syrupi q. s. Fiat massa, et divide in pilulas 1. Of these pills two or three are taken at bedtime, for several nights successively. They purge smartly, and I presume it is by virtue of this property they operate so beneficially as an emmenagogue. 1ST. Chapman. [267. Pills of Phosphoric Acid and Opium.'] R. Acidi Phosphorici glacialis gr. xij ; Pulveris Opii gr. iv ; Syrupi q. s. Misce, et divide in pilulas xij. Signa. — Give one pill every two or three hours. In menorrhagia or uterine hemorrhage. 268. Pills of Digitalis, Myrrh, and Iron, R. Pulveris Digitalis gr. x; Myrrhse gr. xx ; Ferri Sulphatis exsiccataa gr. x ; Syrupi q. s. Fiat massa, et divide in pilulas x. Signa. — Take one pill three times daily. Dr. S. Ashwell recommends these pills in amenorrhoea com- bined with epilepsy. 269. Pills of Aloes, Sulphate of Iron and Cloves, R. Ferri Sulphatis exsiccatas dj ; Pulveris Aloes Socotrinaa 9ij ; Pulveris Caryophylli gr. v; Terebinthinaa Yenetaa q. s. ut fiant pilulas xx. Signa. — One to be taken three times a day. In amenorrhoea. 270. Pills of Citrate of Iron and Strychnia. R. Ferri et Strychniaa Citratis gr. 1 ; Extracti Gentianaa gr. x. Fiat massa, et divide in pilulas xxx. Signa. — One pill three times daily. 116 UTERINE REMEDIES. This double salt is not officinal, and therefore liable to vary in strength. As made in Philadelphia, fifty grains of the compound salt contain one grain of strychnia. It is an ex- ceedingly valuable remedy in chlorosis and amenorrhoea. Fluid Preparations. 271. Decoction of Seneka Snakeroot. B. Senegas contusae 3j ; Aquas Oj. Coque ad f Ixij, dein adde — Aurantii Amari Corticis Iss. Macera per horam dimidiam, et cola. Dr. Chapman observes: "My rule in the administration of this medicide in amenorrhoea is, to give about four ounces of the decoction, more or less, during the day, according to the circumstances of the case. But at the time when the men- strual effort is expected to be made, and until the discharge is actually induced, I push the dose as far as the stomach will allow, having given as much as two ounces every hour." — Therapeutics, vol. ii. p. 38. 272. Mixture of Oil of Erigeroii. B. Pulveris Acacias, Sacchari, aa 3ij ; Aquas f 5j. Tere simul, et adde gradatim — Olei Erigerontis Canadensis, f 3j ; Aquas Menthas Yiridis, f^ij. Fiat mistura. Sigyia. — A dessert-spoonful every two hours. Dr. E. Wilson and others report favorably of the use of this oil in menorrhagia, uterine hemorrhage, and irritable bladder. A. C. Bournonville. 273. Decoction of Cotton Root. B. Gossypii Eadicis contusi 3iv; Aquae bullientis Oij. Misce, coque ad Oj, et cola. Signa. — Dose, a wineglassful. UTERINE REMEDIES. 117 When employed to promote uterine contraction, as a sub- stitute for ergot, Dr. Bouchelle directs this dose to be repeated every twenty minutes. Dr. T. J. Shaw administers the same quantity every hour in dysmenorrhoea. He has great confi- dence in the emmenagogue properties of cotton root. 274. Mixture of Camphor. R. Camphoras 9j; Alcoholis q. s. lit flat pulvis. Dein adde — Pulveris Acacias, Sacchari, aa 3j ; Aquas Cinnamomi f^j. Fiat mistura. This mixture would more properly appear under the head of Narcotics; but as Dr. Dewees considers it particularly effi- cacious in dysmenorrhoea, we have given it a place with Em- menagogues. He directs " one-half the above draught to be given the instant pain is experienced, and if not relieved in an hour or two, the remainder to be given." — Syst. of Mid- wifery, p. 158. 275. Mixture of Ergotine. R. Extracti Ergotas Aquosi gr. xv; Syrupi Aurantii Corticis f sj ; Aquas f Jiij. Misce. Signa. — Dose, a tablespoonful. In uterine hemorrhage this dose should be given every ten or fifteen minutes, until arrested. The remedy has also proved serviceable in other forms of hemorrhage. Bon jean. 276. Mixture of Oantharides, Ammonia, and Gentian. R. Tincturas Gentianse Composite f^jss; Tincturas Cantharidis f 3 j ; Spiritus Ammonise Aromatici f3iij- Misce. Signa. — Give a teaspoonful three times daily. Useful in chlorosis and rrysterical depression. S. ASHWELL. 118 UTERINE REMEDIES. 277. Tinctures of Black Hellebore, Myrrh, and Caniharides. R. Tincturae Hellebori f^ss; Tincturae Myrrhs f 3j ; Tincturae Cantharidis f 3ij. Fiat mistura. Signa. — Dose, thirty drops, three times a day, in a little sugar and water. Eecommended in amenorrhoea. 278. Dewees's Tincture of Guaiacum. R. Pulveris Guaiaci Kesinae 3iv; Sodas vel Potassae Carbonatis 3jss; Pulveris Pimentae 3j ; Alcoholis diluti Oj. Misce. "Digest for a few days. The volatile spirit of am- monia to be added pro re nata, in the proportion of a draehm or two, to every four ounces of tincture." The above formula is different from that adopted in the Phar- macopoeias, for which reason we have inserted it here. Dr. Dewees remarks that, after nearly thirty-five years' experience with this tincture, he has never known it to fail in restoring the suppressed catamenia, when the suppression was an idio- pathic disease. He gives it morning, noon, and night, in doses of a teaspoonful in a little sweetened milk ; and sometimes in a little Madeira, Sherry, or Teneriffe wine. It is occasionally necessary to continue the medicine for some weeks, on which occasion, the dose must be judiciously augmented. — Syst. of Midwifery, p. 149. 279. Volatile Tincture of Guaiacum and Copaiba. R. Tincturae Guaiaci Ammoniatae f §j ; Copaibae f 5ss. Misce. Signa. — A teaspoonful two or three times a day. In cases of amenorrhoea connected with general debility. 280. Tinctures of Iron, Aloes and Myrrh, and Castor. R. Tincturae Ferri Chloridi, Tincturae Aloes et Myrrhae, aa f 3ss ; Tincturae Cast or ei f3ij. Misce. Signa. — Take thirty drops three times a day. This combination of iron and castor, with the elixir pro- prietatis, is indicated in general debility and chlorosis, and UTERINE REMEDIES. 119 the attendant suppression of the menses. It may be given in sweetened water, or in cold chamomile tea. 281. Tincture of Hiera Pier a. R. Pulveris Aloes et Canellae 3jss ; Spiritiis Vini Grallici Oj. Macera per dies decern et cola. Signa. — A teaspoonful may be taken three times a day in sugar and water. A popular and most efficient remedy in amenorrhcea. 282. Emmenagogue Suppository. R. Olei Theobromas iij ; Pulveris Aloes Capensis 3ss ; Castorei, Assafoetidae, aa £ij- Fiant suppositoria xxv. One to be employed daily for several days at the expected period of the menses. Bichard. [283. Liniment of Iodide of Potassium^ R. Potassae Iodidi 3j ; Glycerinas f Jj. Misce. In chronic endometritis with uterine hypertrophy ; to be applied to the cervix uteri. Scanzoni. [284. Liniment of Iodide of Potassium and Opium.] R. Extract! Opii Aquosi gr. xx ; Potassas Iodidi 3ij ; Glycerinas f^j. Misce. To be used as the last in cases attended with hyperassthesia of the uterus and vagina ; may be applied by patient herself through a very small sized speculum. [285. Collodion of Iodine and Tanning R. Iodinii 3ss ; Acidi Tannici 3ij ; Collodii fSj. Misce. An efficient application to the granular surface of an indu- rated and hypertrophied cervix uteri. CLASS IX ANTHELMINTICS. Anthelmintics are medicines employed to destroy and bring away worms from the alimentary canal. They are also termed Vermifuges. The only -unequivocal proof of the existence of worms in the alimentary canal, is the ejection of some of them per anum, or, as sometimes happens, by the mouth. When, in such cases, vermifuges are resorted to, they must be persevered in for several days, with the occasional intervention of an active cathartic. The best vermifuges in many cases are the chaly- beate tonics with some bitter extract. Powders, Pills, and Lozenges. 286. Calomel with Gamboge. B. Hydrargyri Chloridi Mitis gr. v ; Pulveris Gambogias gr. iij. Misce. Signa. — For an adult. To be taken in syrup at bedtime. Gamboge is sometimes given in doses of fifteen or twenty grains for the tapeworm, and is highly spoken of in such cases. 287. Calomel with Pinhroot. R. Hydrargyri Chloridi Mitis gr. iv ; Pulveris Spigeliae gr. x. Misce. Signa. — To be taken two mornings in succession, and on the afternoon of the second day, followed by a dose of castor oil, or senna and manna. — For children upwards of four years old. ANTHELMINTICS. 121 288. Powders of Pinkroot, Savine } and Senna. R. Pulveris Spigelias, Pulveris Sennas, aa 9ij ; Pulveris Sabinae gr. xij. Fiant chart alse vj. Signa. — One every morning till three are taken, then give a dose of castor oil ; if the effect is not produced, the remainder may be exhibited after the same manner. 289. Powders of Common Salt and Cochineal. R. Sodii Chloridi 3iij ; Cocci in pulverem redacti gr. xv. Fiant pulveres vj. Signa. — One every morning for six days, following the last dose with some purgative medicine. Dr. Eush speaks in high terms of this preparation for the expulsion of the long round worms. 290. Powders of Santonin. R. Santonini gr. vj ; Sacchari gr. xv. Misce, et divide in pulveres vj. Signa. — Give one powder night and morning to a child five years old, for worms. [291. Powders of Podophyllin, Santonin, and Iron.] R. Podophyllin gr. J; Santonini gr. iv ; Perri redacti gr. vj. Misce, et divide in chartulas iv. Signa. — Take one every night in syrup. For ascarides and lumbrici, in children two or three years old. 292. Lozenges of Santonin. R. Santonini 3j ; Sacchari Ij ; Mucilaginis Tragacanthse q. s. ut fiat massa, in trochiscos lx clividenda. Signa. — Give one lozenge night and morning. • 293. Powder of Male Fern. R. Pulveris Filicis Maris %j. Signa. — Dose, a teaspoonful. 122 ANTHELMINTICS. The following is Madame Nouffer's plan of treating cases of tapeworm : — "Give of the powder of the Male Fern root, from one to three drachms, in a large cupful of any distilled water, early in the morning. If the stomach should reject it, the powder must be repeated again, as soon as the sickness has gone off, in the same quantity. When it has been upon the stomach about two hours, a strong cathartic bolus (consisting of five grains of gamboge, twelve grains of calomel, and twelve of scammony) must be taken, and worked off with a draught of green tea every now and then ; and its operation may be still farther promoted, if necessary, by half an ounce of salts, dis- solved in warm water. Until the worm comes away, which generally happens on the same day, the patient is to take nothing but broth. If, however, the worm should not be dis- charged, either wholly or in part, the powder is to be repeated with the same regimen the next day." « It has been suggested, and with some probability, that the purge directed to follow this medicine is the more efficient of the two. 294. Powder of Kameela. R. Kottleras £ij. Divide in pulveres iv. Signa. — Take one powder every hour, in syrup or aromatic water. Kameela is a powder brushed off the capsules of an East Indian shrub, the Rottlera tinctoria. It is used in India as a dye for silks, imparting to them a fine yellow color. Dr. McKinross, in 1853, made known its powers in the treatment of tapeworm. Many British practitioners have since tried it, and confirm his favorable testimony. It may be given in powder, in doses of thirty to sixty grains; or one or two teaspoonfuls of a tincture made by displacing four ounces of the powder in a pint of alcohol. In full doses, it causes purg- ing, with some nausea or even vomiting. 295. Lozenges of Precipitated Carbonate of Iron. R. Vanillae 3j ; Sacchari Jxv. Tere simul et adde — Ferri Subcarbonatis Iv; Mucilaginis Tragacanthae q. s. Contunde in massam, et divide in trochiscos singulos gr. xx pendentes. Signa. — One lozenge may be taken several times daily. ANTHELMINTICS. 123 This formula, devised by Mr. B. Parrish, furnishes to the practitioner a mode of administering the subcarbonate of iron to children in an agreeable and effectual form. Of this remedy, as an anthelmintic, the late Professor Bush had a very favorable opinion. He gave it in doses of from five to thirty grains to children of from one year old to ten, and sometimes in half ounce doses, with safety and success. — See Observ. and Inquiries, p. 243. 296. Pills of Venice Turpentine, Calomel, etc. B. Terebinthinas Yenetas 5j ; Extracti Jalapas 3ss; Extracti Hyoscyami gr. iv; Hydrargyri Chloridi Mitis gr. viij. Fiat massa, et divide in pilulas singulas gr. ij pendentes. Signa. — Of these, four are to be taken every three hours; and during the entire period of their use, the patient is to take only weak broth, tea, or coffee. Used in tapeworm. Hitfeland. Infusions, Decoctions, etc. 297. Compound Infusion of Pinkroot, or Worm-tea. R. Spigelias contuses ^ss; Sennas 3ij; Mannas sj ; Sabinas 9ij ; Eoeniculi 3ij ; Aquas bullientis Oj. Macera per horas duas et cola. Signa. — Dose, a tablespoonful three times daily, for three days, for a child four or five years old. If it purge too actively, it should be discontinued. Worm tea has stood the test of many years' experience in Philadelphia, and has proved itself one of the most efficient agents for the expulsion of the long round worm. 298. Decoction of the Bark of Pomegranate Root. R. Granati Eadicis Corticis, 3jss ; Aquas, Ojss. Coque ad Oj, et cola. Signa. — Take a wineglassful every two hours. 124 ANTHELMINTICS. This decoction is employed, almost exclusively, for the de- struction of tapeworm. "The efficacy of the bark of the root of the pomegranate, as a remedy for the tapeworm, is now well established in India." Pakis, vol. ii. p. 173. 299. Infusion of Kousso. R. Brayerse iss ; Aquae bullientis f^x. Macera per horam dimidiam. Signa. — Dose, a teacupful every half hour. To be used for tapeworm. The only preparation necessary is, that the last meal of the preceding evening should be slight. The previous evacuation of the bowels, by a mild purgative or a lavement, is also de- sirable. The mode of administering the remedy is as follows : "A little lemon-juice is to be swallowed, and the infusion being stirred up, the whole is taken, liquid and powder, at two or three draughts, at short intervals, being washed down by cold water and lemon-juice. To promote the operation, tea (without sugar or milk) may be taken. In three or four hours, if the remedy has not operated, a dose of castor oil or a saline purgative should be administered." Jon. Peeeiea. Electuaries, Mixtures, etc. 300. Electuary of Tin. R. Pulveris Stanni ^j ; Syrupi fusci f^iv. Misce. Signa. — Two tablespoonfuls may be given early in the morn- ing, to be repeated every two hours until the whole be taken, and then followed by an active cathartic. The efficacy of this substance is said to be increased by combination with sulphur, by which means sulphuretted hy- drogen is generated, and the worm destroyed by the offensive gas. Larger doses are sometimes prescribed. 301. Electuary of Cowhage. R. Mucunse 3j; Mellis despumati q. s. ut flat electuarium. Signa. — Dose, a teaspoonful to a child two or three years old ; to be given before breakfast in the mornings of three suc- cessive days, and then followed by a brisk cathartic. In lumbrici. ANTHELMINTICS. 125 [302. Mixture of Wormseed and Rhubarb.] B. Potassae Carbonatis pur as 3jss ; Extracti Ehei fluidi f 3jss ; Olei Chenopodii gtt. xxv ; Liquoris Calcis f §iv. Misce. Signa. — Give a teaspoonfal every two hours until purged. A very efficient vermifuge. L. C. Heyl. 303. Mixture with Oil of Wormseed. B. Olei Chenopodii f 3jss ; Olei Eicini 3iij ; Olei Anisi gtt. x. Misce, et adde — ■ Syrupi Ehei Aromatici, f 3j. Fiat mistura. Signa. — Shake the bottle well before using. Give a teaspoon- ful night and morning to a child two years old. This mode of exhibiting the oil has been extensively tried in Baltimore, and has proved effectual. — Am. Journ. Pharmacy, p. 306, 1850. 304. Another Form. B. Olei Chenopodii f3j ; Sacchari, Pulveris Acacias, aa 3ij ; Aquae Menthae Piper itae f^ijss. Misce secundum artem. Signa. — A teaspoonful of this preparation may be given four times a day for two days in succession, and then be purged off with castor oil or salts, for children of three to eight years old. This is a vermifuge of considerable reputation in this coun- try. It is generally used in lumbrici- and ascarides; though we have heard of its having been successfully given for taenia, but in much larger doses. S. G. Moeton. 305. Fluid Extract of Pinkroot and Senna with Santonin. B. Extracti Spigeliae et Sennae Fluidi f^ij; Santonini gr. xvj. Misce. Signa. — Give a child, two years old, a teaspoonfal night and morning, until purging takes place. 126 ANTHELMINTICS. This fluid extract, originally devised by Prof. Procter, has been used successfully in Philadelphia for the last ten years in the treatment of lumbrici. 306. Mixture of the Extract of Male Fern. R. Olei Filicis Maris 3ss ; Mellis Kosse 3ss. Misce. Signa. — Take one-half at bedtime, and the remainder early in the morning, on an empty stomach. Used for tapeworm. If the worm does not come away in six or eight hours after the last dose, administer some mild purgative. The oil indicated in this prescription is in reality a fluid extract prepared with ether. Kadius. 307. Linctus of Oil of Turpentine. R. Olei Terebinthinas Jij ; Mellis despumati aj. Misce, et fiat linctus. Signa. — Dose, a dessert-spoonful. The late Prof. Chapman had great confidence in the oil of turpentine as a remedy for tapeworm, and was in the habit of giving it in large doses at brief intervals. B. Ellis. 308. Emulsion of Pumpkin Seeds. R. Peponis §ij. Decortica et contunde in massam cum Sacchari Ij. Dein adde gradatim — Aquas flviij. Misce. Signa. — The whole to be taken in two or three draughts, at short intervals, fasting. The efficacy of an emulsion of pumpkin seeds in expelling tapeworm is now established beyond doubt, as it has been ad- ministered repeatedly and successfully, both in the West In- dies and this country. The above is the formula of the late Dr. H. S. Patterson, who was among the first to introduce the remedy to the notice of American practitioners. The expressed oil of the seeds has also been tried in the dose of half an ounce, with a degree of success. ANTHELMINTICS. 127 Clysters. Enemata are the most certain of all remedies in ascarides ; they may be made of various substances, such as solution of assafetida, of common salt, sulphur, pure olive oil, soap, aloes, etc. etc. For children, thirty grains of aloes should be dis- solved in half a gill of water ; to this add a tablespoonful of sweet oil, and administer the half of the mixture on going to bed. The other half the next night, if necessary. Or aloes may be given in mucilage, as in the following formula : — 309. Aloetic Enema. B. Aloes Capensis 5j ; Mucilaginis Ulmi Oj. Fiat enema. Signa. — The half of this may be given to a child eight or ten years old. In ascarides. 310. Enema of Camphor and Sweet Oil. B. Camphorae 5j ; Olei Olivse lij. Misce pro enemate. This preparation is particularly adapted to ascarides, and should be freely thrown np the rectum for three or four suc- cessive nights. No remedy is more effectual than this in re- lieving the intolerable itching caused by those worms. 311. Anthelmintic Clyster. B. Hydrargyri Iodidi Eubri gr. |; Potassii Iodidi gr. viij. Tere simul, et adde gradatim — Aquas destillatas Oj. Signa. — Inject a wineglassful night and morning. The injections should be continued for two or three days, and be repeated once or twice at the end of two weeks. When thus employed, the remedy seldom fails in the removal of seat- worms (ascarides). The dose prescribed is for a child. Trousseau, CLASS X. STIMULANTS. In the use of stimulants, it is for the most part advisable to begin with small doses, and augment them as circum- stances may require. There are cases, however, in which it is necessary to give them plentifully from the first. It will be often requisite to change not only the stimu- lating substance, but the part of the body to which it is applied ; thus, when the stomach fails, the rectum and skin may be acted upon with advantage. Pills, Powders, etc. 312. Pills of Camphor, Cantharides 1 and Opium. R. Pulveris Cantharidis gr. xviij ; Pulveris Opii, Camphorse, in pulverem cum alcohole redactse, aa gr.xxxvj ; Confectionis Kosse q. s. ut fiant pilulse xxxvj. Signa. — One may be taken every night on going to bed. In impotency from general debility. 313. Pills of Turpentine and Guaiacum. R. Pulveris Guaiaci Eesinse 5j; Terebinthinse Venetse q. s. ut fiant pilulas xv. Signa. — One three times a day. These pills have a powerful effect upon the urinary organs. They are employed in gleet and leucorrhoea, but frequently produce strangury. STIMULANTS. 129 314. Pills of Cayenne, Pepper. R. Pulveris Capsici gr. xxiv ; Extracti Gentianse gr. xvj. Misce, et fiant pilulae xij. Signa. — One, four times a day. Used in debility of the stomach, from intemperance. St. Bart. Hospital. 315. Creasote Pills. R. Creasoti n^iij ; Pulveris Hyoscyami Folii gr. xij ; Confectionis Aromaticae q. s. Fiat massa in pilulas xij dividenda. Signa. — Take one pill three times daily. Used to allay the morning sickness in pregnancy. PlTSCHAFT. 316. Pills of Valerianate of Quinia. R. Quiniae Yalerianatis gr. xij; Pulveris Tragacanthae gr. vj; Aquas q. s. ut fiat massa in pilulas viij dividenda. Signa. — Give one pill every hour. Used in hemicrania. The late Dr. Joseph Parrish was in the habit of treating hemicrania successfully, by a combination of Peruvian bark and valerian. This formula contains the active constituents of both remedies in a concentrated form. It has afforded prompt relief in numerous instances. Mixtures and Infusions. 317. Mixture of Carbonate of Ammonia. R. Ammoniae Carbonatis Jj; Sacchari, Pulveris Acaciae, aa 5jss; Aquae Menthas Viridis f siv. Fiat mistura. Signa. — A tablespoonful every two hours. As carbonate of ammonia sustains the action of the heart, 9 130 STIMULANTS. without stimulating the brain, it is resorted to whenever the vital powers begin to fail, in diseases of nearly every type. [318. Effervescing Ammonia Mixture.'] R. Ammonias Carbonatis 3ij; Acidi Hydrocyanici diluti nixx; Tincturas Cardamomi Composite f3yj ; Infusi Aurantii q. s. nt fiat mistura f Jviij. Signa. — Put two tablespoonfuls into one third of a tumbler of water ; add a tablespoonful of fresh lemon-juice, and drink while foaming, three or four times daily. In acidity of stomach, with depression. Tanxer. 319. Draught with Valerian and Carbonate of Ammonia. R. Olei Valerianae gtt. iij; Ammonias Carbonatis gr. x ; Aquas Cinnamomi f^jss; Syrupi f 3ss. Fiat haustus. Signa. — One-half to be taken every fourth hour. In nervous headache, and depression of spirits. 320. Draught of Carbonate of Ammonia and Ginger. R. Pulveris Zingiberis gr. xv; Ammonias Carbonatis gr. viij ; Tincturas Cinnamomi f 3ij ; Aquas f ijss. Misce. Signa. — To be taken at once. In gout or cramp of the stomach. 321. Elixir of Valerianate of Ammonia. R. Ammonias Yalerianatis 3j ; Aquas Aurantii Florum f^ij; Syrupi, Spiritus Curacoa, aa f3J. Misce. Signa. — Dose, a teaspoonful. Used in hysterical affections and disorders of the nervous system. STIMULANTS. 131 322. Mixture of Valerian and Cajeput Oil. R. Extracti Valeriana Fluidi f5ij ; Olei Cajuputi tt^xvj. Tere simul et adjice — Syrupi Acacias f 3yj ; Aquae Aurantii Florum f 3J. Misce. Signa. — Dose, a teaspoonful. This is a mild and effectual stimulant, with a specific tend- ency to the nervous system. It may be used beneficially to correct hiccough, twitchings of the muscles, restlessness. It is also employed in hysteria. 323. Mixture of Oil of Turpentine. R. Olei Terebinthinas 3j ,* Pulveris Acacias, Sacchari, aa 3ij ; Tinctures Opii gtt. lx ; Spiritus Lavandulae Compositi f3ij ; Aquas Menthas Yiridis f^v. Fiat mistura. Signa. — A tablespoonful for a dose, every two hours. This remedy has gained great reputation in some of the low forms of fever. The author once employed it in the dose pre- scribed above, in passive hemorrhage from the bowels, with complete success ; and in hemorrhage from the bladder, result- ing from low fever, it has been given with equal advantage. B. Ellis. 324. Camphor Mixture. R. Camphoras, in pulverem cum Alcohole redactas 3j ; Pulveris Acacias, Sacchari, aa 3jss; Tincturas Opii gtt. xl ; Aquas Menthas Viridis fjiv. Fiat mistura. Signa. — A tablespoonful to be given every two hours. Used in typhoid and nervous fevers. B. Ellis. 132 STIMULANTS. 325. Camphor Julep. R. Camphoras, in pulverem redactas 3ss; Aquas bullientis f^viij. Macera per horam dimidiam, in vase leviter clause-, et cola. Signa. — A tablespoonful for a dose. Many of the older practitioners were in the habit of using a hot camphor tea, in dysmenorrhcea, under an impression that its virtues are better developed. It certainly is stronger hot than cold, but in neither case is it equal to the officinal cam- phor-water (aquae camphorae) which contains three grains to the fluidounce when properly prepared. 326. Camphor and Myrrh Mixture. R. Camphorae 3j ; Myrrhae 3ss. Tere simul et adde gradatim — Sacchari §j ; Aquas fivj. Misce. Signa. — A tablespoonful to be given every two hours. Chiefly used in dysmenorrhcea. 827. Mixture of Camphor and Chloroform. R. Camphorse 3ij ; Chloroformi puriflcati 3j ; Yitelli unius ovi ; Aquae f §iv. Fiat mistura. This mixture affords us the means of administering large doses of camphor, in as concentrated a form as it would be safe to give a local irritant. It can be diluted with water without precipitation. Each teaspoonful contains four grains. Smith. 328. Solution of Camphor in Ether. R. Camphorse 3ss; ^Etheris f gj. Solve. Signa. — Take ten drops every twenty minutes. Used in cholera morbus and cholera. " I have found nothing so effectual in giving relief to the nausea and vomiting of the early stages of cholera as small doses of this solution, frequently repeated." John Eberle. STIMULANTS. 133 329. Mixture of Paregoric and Ammoniated Guaiacum. R. Tincturae Opii Camphoratae, Tincturae Gruaiaci Ammoniatae, aa f^j. Fiat mistura. Signa. — Two teaspoonfuls in sweetened water every two hours. In misplaced and retrocedent gout. 330. Yeast Mixture. R. Fermenti f^x; Camphoras 3ss; Spiritus iEtheris Nitrosi f 3ss. Fiat mistura. Signa — Take a tablespoonful every two hours. This was extensively used in the late typhus epidemic in Ireland, as a stimulant and antiseptic, and with the happiest results. Lampeey. 331. Assafetida and Spirit of Ammonia. R. Spiritus Ammonias Aromatici f3ij; Tincturae Assafoetidae f3vj. Misce. Signa. — Give a teaspoonful, in sweetened water, every four hours. An excellent stimulus in nervous debility and hysteria. 332. Emulsion of Phosphorus. R. Phosphori gr. ij ; Mucilaginis Acacias flj. Tere simul, et adde gradatim — Aquae f 3v. Fiat emulsio, dein adde — Syrupi f %] ; Spiritus JEtheris Compositi n^xxx. Fiat mistura. Signa. — The usual dose is a tablespoonful every three or four hours. Used in amaurosis, palsy, epilepsy, etc. Hufeland. As the violence of phosphorus as a remedy, and its very great power, are generally known to physicians, we need hardly repeat the necessity there is for the greatest caution in its administration. 134 STIMULANTS. The subjoined is one of the many formulas adopted in Europe. 333. Lobstein's Phosphorated Ether. R. Phosphori gr. ij ; Solve in iEtheris f sss. Dein adde — Spiritus Menthae Piperitae f5ss. Signa. — Take six drops on sugar every three hours. The bottle should be carefully stoppered, and covered with dark paper. Used in epilepsy, paralysis, and amaurosis. Foy. 334. Phosphorated Oil. R. Phosphori concisi gr. vj; Olei Amygdalae Dulcis 3j. Liqua cum leni calore. Post refrigerationem, cola. Signa. — Dose, ten drops every three hours in mucilage. Advised in chronic rheumatism and gout. It is also used externally by friction in the same complaints, and for con- tracted tendons. Ph. Borussica. 335. Glyeerole of Phosphorus. R. Phosphori concisi gr. ij; Glycerinae f 3J. Solve cum leni calore. Signa. — Dose, ten minims. Used for the same purposes, and proposed as a substitute for the above phosphorated oil. J. L. Crawcour. 336. Mixture of Arnica. R. Arnicas 3ij ; Aquae bullientis Oss. Macera per horas duas et cola. Dein adde — Tincturae Arnicas f 3ij ; Tincturae Cardamomi f 3yj. Misce. Signa. — A tablespoonful three times a day. Recommended for the relief of tinnitus aurium. The dose to be gradually increased. It is also useful as a stimulant in atonic gout. Wilde. STIMULANTS. 135 337. Mixture of Chlorinated Lime. B. Calcis Chlorinate 9j ; Aquas fliij. Solve et cola. Dein adde — Syrupi Zingiberis f sj. Fiat mistura. Signa. — Take a tablespoonful every three hours. Chlorinated lime is stimulant and antiseptic, and has been used beneficially in typhoid, typhus, and scarlet fevers. Eeid. 338. Infusion of Cayenne Pepper and Salt. R. Pulveris Capsici Iss ; Sodii Chloridii 3j ; Aceti bullientis, Aquas bullientis, aa f ^viij. Macera per horam unam et cola. Signa. — Dose, a tablespoonful every two hours. This combination was employed in an epidemic of malig- nant scarlet fever in the West Indies with the happiest results. It was used both internally and as a gargle. Stephens. 339. Mixture of Soda and Cubebs. R. Pulveris Cubebas 3ij ; Sodas Carbonatis 3ss ; Mucilaginis Acacias fjvj ; Aquas Menthas Viridis f 3vj. Fiat mistura. Signa. — Take a tablespoonful every hour and a half. Useful as an antacid and carminative. Fosbeoke. 340. Mixture of Bismuth and Cubebs. B. Pulveris Cubebas 3ij ; Bismuthi Subnitratis 3ss ; Mucilaginis Acacias f Jss ; Syrupi f 3yj ; Aquas fgvj. Fiat mistura. Signa. — Take a tablespoonfal four times a day. We have extracted this and the preceding prescriptions from a paper of Mr. John Fosbroke, surgeon, Chittenham. (See Medical Recorder for April, 1825.) 136 STIMULANTS. They are recommended in various affections of the mucous membranes, viz., of the bowels, bladder, trachea, etc. 341. Mustard Whey. K. Lactis Yaccinas Oj ; Sinapis Albas contusas Ij. Coque cum leni calore, ad perfectam casei separationem, cola et adde — Yini Xerici f Ivj. Signa. — A draught of this whey may be taken every hour or two in low fever and in debilitated stomach. 342. Wine Whey. B. Lactis Vaccinas bullientis Oss; Yini Xerici fliv. Misce, cola, et adde — Sacchari Ij ; Myristicas rasuras q. s. ad gratum saporem. Misce. There are few mild stimulants more employed, or more useful than wine whey. Dr. Chapman speaks of it as possess- ing a kindred action with carbonate of ammonia. The dose to be regulated by the circumstances of the case ; from four ounces to a pint during the day. 343. Wine and Egg Mixture. R. Yitellum unius ovi ; Olei Cinnamomi gtt. x. Contunde simul, et adde — Yini Xerici, Aquas Cinnamomi, aa f 5jss ; Sacchari 3j ; Aquas destillatas flj. Fiat mistura. Signa. — Give a wineglassful, at short intervals, in convales- cence from low fevers. 344. Egg-Nogg. R. Albumen et Yitellum unius ovi ; Sacchari Albi 3ij- Misce, et contunde in spumam. Dein adde — Yini Xerici f Iss; Aquas f Ij ; Myristicas rasuras q. s. ad gratum saporem. Misce. STIMULANTS. 137 This delightful mixture is both stimulant and nutritious. In the formula, both the white and the yelk of the egg are directed to be beaten with the sugar ; but if it be desirable to have the preparation very light and delicate, it is better to beat the yelk to a froth and mix with the wine, sugar, and nutmeg, and then add to the mixture the white of the egg, previously beaten to a froth in a separate vessel. 345. Milk Punch. R. Spiritus Yini Gallici f oij ; Lactic Vaccinas f.^iv; Sacchari gss ; Myristicas rasurse q. s. ad gratum saporem. Signa. — Take a tablespoonful every hour or two in low fevers. 346. Oleo-Saccharoles. Under the name of oleo-saccharum, M. Beral has introduced into European pharmacy a convenient mode of exhibiting the volatile oils. It is simply a combination of any volatile oil with sugar, the latter serving the double purpose of rendering the former soluble in water, and covering its taste. The pro- portions are, one drop of oil to one drachm of sugar. They are to be carefully mixed by trituration. They act as mild carminatives. CLASS XI. SAEOOTICS. Nabcotics have been denominated sedatives, from their power of diminishing action ; anodynes, from their capability of alleviating pain; and hypnotics, or soporifics, from their power of inducing sleep. A few words only will be necessary as general rules for their administration, and any peculiarities that individuals of the class may possess will be noticed under the appropriate prescriptions. It is well known they possess the power of fulfilling two indications ; namely, of exciting and depressing the nervous energy. To obtain the first of these results, it is necessary to begin with small doses, and repeat them frequently ; while in order to arrive at the second, a full dose must be given, and not resorted to again for a considerable length of time. We should also bear in mind that the system very soon becomes habituated to their action, and the doses must be continually enlarged when it is necessary to maintain their impression. The difference between the susceptibility to their action when the body is in a morbid or healthy condition, should not be overlooked. Pills. 3-i7. Pills of Opium. B. Pulveris Opii gr. xij ; Saponis gr. iij. Misce, et divide in pilulas xij. Signa. — One is the ordinary dose to produce sleep. In equal weights of powdered and soft opium, the former is much the more powerful, the latter containing a considerable proportion of water. This should be recollected in directing the medicine in the form of pills. NAECOTICS. 139 An opium pill that has been made long enough to become perfectly hard and dry, will be retained by an irritable stomach when a fresh one would be rejected. 348. Pills of ' Lupulin. R. Lupulinas 3ss; Contunde in mortario, et divide in pilulas x. Signa. — Two pills may be given for a dose, and the quantity be doubled if necessary. This substance, we are told by Dr. Ives, contains all the active properties of the hop. It is slightly narcotic, and is serviceable in irritable stomach, and as a preventive of noc- turnal erections in different forms of acute venereal disease. 349. Pills of Sulphate of Morphia. R. Morphias Sulphatis gr. ij ; Confectionis Kosas q. s. ut fiant pilulas xij. Signa. — One may be given for a dose. One grain of either of the salts of morphia is usually esti- mated as equal to six of opium ; so that a pill of the above prescription will be equivalent to a grain of opium. 350. Pills of Lactucarium and Hemlock. R. Lactucarii gr. xij ; Extracti Conii Alcoholici gr. vj. Misce, et divide in pilulas vj. Signa. — One for a dose, to be repeated in two hours, if sleep be not procured. The inspissated juice of the garden lettuce is said to act as a direct sedative, lessening the frequency of the pulse, dimin- ishing the natural heat, and procuring sleep, without inducing the subsequent distressing effects which follow the use of opium. The thridace of the French appears to be prepared by a different process from that employed in the preparation of the British lactucarium. The former is not so highly esteemed in this country as the latter. 351. Pills of Henbane and Ipecacuanha. R. Extracti Hyoscyami Alcoholici gr. x; Pulveris Ipecacuanhas gr. v. Misce, et divide in pilulas x. Signa. — One every two hours until relief is procured, watch- ing the effect. Used in flatulence and irritability of the bowels. 14:0 NARCOTICS. 352. Pills of Opium and Henbane. R. Pulveris Opii gr. v; Extracti Hyoscyami gr. xv. Fiat massa, in pilulas x dividenda. Signa. — One every night when an anodyne is required. Henbane is a favorite anodyne remedy with English prac- titioners. When given in combination with opium, it modifies the unpleasant effects experienced by some persons from the use of the latter alone. [353. Pills of Opium and Colocynth.'] R. Pulveris Opii gr. vj ; Extracti Colocynthidis Compositi gr. xxiv ; Syrupi Acacias q. s. ut fiat massa in pilulas xij dividenda. Signa. — One every hour till purging is produced. In lead colic, and obstruction from impaction of feces. J. F. Meigs. 354. Pills of Camphor and Opium. R. Camphorge in pulverem redactas 9ij ; Extracti Opii gr. viij. Mucilaginis Tragacanthas q. s. ut fiat massa in pilulas xvj dividenda. Signa. — Take two pills every night at bedtime. Used for spasm of the urethra, and to prevent nocturnal erections. Kicord. 355. Pills of Opium and Digitalis. R. Pulveris Opii, Pulveris Digitalis, aa gr. vj. Confectionis Kosas q. s. ut fiant pilulas xij. Signa. — One to be taken every four hours. In asthma. [356. Compound Anodyne Pill.] R. Extracti Cannabis Indicas, Extracti Belladonnas, Extracti Nucis Yomicas, aa gr. ij ; Extracti Valerianae, Quinias Sulphatis, aa gr. xij. Misce, et divide in pilulas xij. Signa. — Take one pill every two hours until relieved. NARCOTICS. 141 A very efficient pill in simple neuralgia, especially cepha- lalgia, from cerebral irritation or excessive mental activity. The extracts of the narcotics should be carefully selected. [357. Anaesthetic Pill'] R. Morphias Sulphatis gr. viij; Camphoras gr. xx ; Olei Cajuputi gtt. x; Pulveris Tragacanthas gr. v ; Extracti Grentianas gr. xv ; Syrupi Acacias q. s. Misce, et divide in pilulas c. Signa. — Take two or three at a dose, to be repeated every half hour till relieved. For abdominal pain, colic, or cholera. J. F. Meigs. 358. Pills of Extract of Conium and Calomel R. Extracti Conii 3ss ; Hydrargyri Chloridi Mitis gr. v. Fiant pilulas xv. Signa. — One three times a day. Used in painful syphilitic affections. 359. Pills of the Extract of Nux Vomica. R. Extracti Nucis Vomicae Alcoholici, Pulveris Extracti Glycyrrhizas, aa 9j. Misce, et riant pilulas xl. Signa. — Take one pill three times daily. Recommended in general and local palsies, in paralysis of the sphincters, and for incontinence of urine. Radius. 360. Pills of Camphor ) Assafelida, etc. R. Camphoras, Assafcetidas, aa 3j ; Extracti Belladonnas 3ss ; Extracti Opii gr. x. Contere in massam, et divide in pilulas lx. Signa. — One pill is given night and morning, or at shorter . intervals, according to the urgency of the case. Used in hysteria. Debreyne, 142 NARCOTICS. 361. Pills of Aconite and Dover's Powder. R. Extracti Aconiti Alcoholici gr. vj ; Pulveris Ipecacuanliae Compositi gr. xij ; Syrupi q. s. ut flat massa, in pilulas vj dividenda. Signa. — Take one pill three times a day. Used in chronic rheumatism. Mixtures, etc. 362. Laudanum. R. Tincturse Opii flj. Signa. — Dose, twenty-five drops. As the regulation of doses for children is, to the young practitioner, one of the most difficult parts of prescribing, and as laudanum is an article so universally employed in their diseases, we subjoin the following graduated table from Dr. Dorsey's Syllabus, page 36, 1817, giving the maximum doses for all ordinary conditions : — For a child at birth or within a month after i- to 1 drop. Under a year old . J to 3 drops. From one to two years of age 1 to 5 " From two to five u 2 to 8 " From five to ten tt 5 to 15 " From ten to fifteen a . 10 to 20 " At fifteen years . . . . . 15 to 20 " For an adult . . . . . 25 to 30 " It is important in the employment of laudanum that it should be of the proper strength and perfectly transparent. For these reasons, it should be obtained from the apothecary in small quantities, as it is liable to deposit part of the opium ; hence the liquid near the surface is weaker, and the dregs correspondingly stronger. Infants have been destroyed by the exhibition of thick laudanum. Physicians, therefore, should never trust a nurse to administer a dose to a child, except under circumstances of extreme urgency, carefully examining the bottle previously. B. E. 363. Officinal Preparations of Opium.- As each of the numerous preparations of opium presents some peculiarities, which, at times, renders it preferable to all others for internal exhibition, the following statement of the NAKCOTICS. 143 opium-strength of each may prove valuable as a guide in pre- scribing : — 13 minims or 25 drops of laudanum (Tinctura Opii); 13 " or 25 " of the elixir of opium (Tinctura Opii Deodorala) ; 7 or 10 " of black drop (Acetum Opii); 10 " or 20 " of the acetated tincture (Tinctura Opii Acetata) ; 80 " or 80 " of ammoniated tincture (Tinct. Opii Ammoniata, Ed.); or 15 " of wine of opium or Sydenham's lau- danum ( Vinum Opii) ; A tablespoonful of paregoric (Tinct. Opii Camphor uta); Thirty-six grains of the confection (Confectio Opii)] Half a grain of the extract (Extractum Opii) ; and Ten grains of Dover's powder (Pulvis Ipecacuanhse Compo- situs), contain, respectively, one grain of opium. About five grains of opium, or a small teaspoonful of lauda- num, may be considered as equivalent to one grain of morphia, or of any of its salts. E. P. T. 364. Solution of Sulphate of Morphia. R. Morphias Sulphatis gr. j ; Aquae destillatae f£j. Fiat solutio. Signa. — Dose, one teaspoonful. Used in the same cases as opium. When morphia and its salts were first introduced, the for- mulas given by Magendie were generally adopted, and are still retained in New York, and some other places. These contain sixteen grains of the sulphate or the acetate of morphia in a fluidounce of water ; whereas the officinal solution has but one grain to the ounce. Practitioners should avoid confounding the two solutions. 365. Syrup of Sulphate of Morphia. R. Morphiae Sulphatis gr. viij ; Aquas destillatae fgiv. Solve, et adde — Syrupi f^iv; Spiritus iEtheris Compositi f3j. Misce. Signa. — Dose, a teaspoonful. 144: NARCOTICS. This is, virtually, of the same strength as the officinal solu- tion, and has the advantage of being more durable as well as more palatable. J. T. Plummee. 366. Mixture of Laudanum and Oil of Turpentine. R. Tincturae Opii f^j ; Olei Terebinthinas f Iss. Misce. Signa. — A teaspoonful, diluted, every hour or two may be given in delirium tremens, its effect being closely watched. The turpentine may be added or omitted at the discretion of the physician, and the quantity of laudanum in some cases may be doubled. We have successfully given two teaspoon- fuls every hour until two ounces of laudanum were taken. We do not believe in the doctrine, however, that opium in this disease may be administered almost ad libitum without danger. On the contrary, we feel assured that death has been caused by its excessive use in delirium tremens. S. G. Morton. 367. Mixture of Lupulin. R. Tincturae Lupulinae f*j ; Syrupi Amygdalae fgj ; Aquas f Hij. Misce. Signa. — Dose, a tablespoonful every two hours. Dr. G. B. Wood recommends the tincture of lupulin in the treatment of delirium tremens, both as an adjuvant to opium, and as a substitute for it. By checking vomiting, and quiet- ing restlessness, it promotes sleep. 368. Mixture of Camphor Water and Hoffman' s Anodyne. R. Aquae Camphorae foiij; Spiritus iEtheris Compositi, Syrupi Amygdalae, aa f jjjss. Misce. Signa. — Dose, a dessert-spoonful every two hours. Used in nervous affections, and the sleeplessness of fever. 369. Mixture of Chloride of Propylamin. R. Propylamini Chloridi gr. xxxvj ; Sacchari 3ij ; Aquae Menthae Piperita^ fSvj. Fiat solutio. Signa. — A tablespoonful every two hours. NARCOTICS. 145 370. Elixir of Propylamin. R. Propylamini Chloridi 9ij; Aquae fsiijss. Solve et adde — Syrupi fsss ; Spiritus Curacoae foj. Misce. Signa. — Dose, a teaspoonful. Given in rheumatism. In this preparation the unpleasant odor and taste of the propylamin are overcome by the use of syrup and Curacoa cordial. Each fluidrachm contains one grain of the chloride of propylamin. P. H. Stabler. 371. Mixture of Iodide of Propylamin. R. Propylamini Iodidi gtt. xxv; Sacchari 3ij ; Aquae Menthae Piperitae f^vj. Misce. Signa. — A tablespoonful every two hours. Used, like the other preparations of propylamin, in the treatment of rheumatism. The presence of iodine is claimed as an important element in this combination. B. J. Crew. 372. Strychnia Mixture. R. Strychniae gr. j ; Acidi Acetici gtt. ij ; Sacchari 5ij ; Aquae destillatae f^ij. Fiat solutio. Signa. — A teaspoonful morning and evening. Prescribed in palsies. It has also proved beneficial in the vomiting of pregnant women, when given in smaller quantities and at shorter intervals. Magendie. 10 146 NARCOTICS. 373. Solution of Extract of Belladonna. B. Extracti Belladonna gr. iij ; Syrupifjj; Aquae Cinnamomi f 3vij. Fiat solutio. Signa. — Give three drops thrice a day, to a child under a year old, and an additional drop for every additional year. Belladonna has been recently used in Germany as a pre- ventive of scarlatina. The extract, if given for several days, produces a scarlet eruption and affection of the fauces, analo- gous to those of scarlatina ; and it is pretended that this fac- titious disease is sufficient to prevent the access of the real one. S. G. Morton. 374. Mixture of Chloric Ether. R. JEtheris Chlorici f^jss; Aquae Camphor as fSij ; Syrupi Amygdalae fsss. Misce. Signa. — A dessert-spoonful in water every three hours. As prepared by the manufacturing chemists of Philadelphia, chloric ether is of a uniform strength, and a reliable article. It is less narcotic than chloroform, but more stimulating. It has proved of great service in the treatment of many nervous and painful affections unattended by active inflammation. C. Evans. 375. Chloroform Mixture. R. Chloroformi purincati 3ij ; Olei Cinnamomi gtt. viij ; Spiritus Camphorae, Tincturae Opii, aa f3jss ; Alcoholis fSiij. Misce. Signa. — The dose ranges from five to thirty drops, in sweet- ened water. This preparation has proved highly serviceable in the relief of the pains and cramps of colic, cholera morbus, and cholera asphyxia. H. Hartshorne. NARCOTICS. 147 [376. Chlorodijne.] R. Chloroformi f 3 vj ; JKtheris Chlorici f 3j ; Tincturse Capsici f3ss; Olei Mentha Piperita gtt. ij ; Morphias Hydrochloratis gr. viij ; Acidi Hydrocyanici diluti gtt. xxiv; Acidi Perclilorici gtt. xx ; Tincturae Cannabis Indicas f 3j ; Syrupi fusci f3j. Misce. Signa. — Give 20 drops as a soporific, and 30 drops to a fiui- drachm as an anodyne in cholera or violent paroxysms of pain. This remedy has acquired a great reputation from its first introduction as a nostrum under the above name. Gooley. [377. Another Form.] R. Chloroformi f £iv ; ^Etheris f I] ; Alcoholis f liv ; Syrupi fusci fsiv; Extracti Grlycyrrhizas iijss; Morphias Hydrochloratis gr. viij ; Olei Menthae Piperitas nixvj ; Syrupi f^xvijss; Acidi Hydrocyanici diluti f^ij. Misce secundum artem. Signa. — Dose, from five to ten minims. In pain, diarrhoea, or spasmodic affections. Known also as the compound tincture of chloroform. P. Squire. 378. Chloroform Mixture. R. Chloroformi 3j ; Yitellum unius ovi. Tere simul et adde — Sacchari 3ij; Aquae f^ij. Fiat mistura. Signa. — Dose, a dessert-spoonful every two hours. Prescribed in gastrodynia, flatulent colic, and cholera mor- 148 XAECOTICS. bus. Owing to the antiseptic properties of the chloroform, this mixture keeps well. It is used in the same eases as the preceding formula?. [379. Chloroform and Tincture of Cardamom .] R. Chloroformi ^Ixv. Tincturae Cardamomi Composite Ojss. Misce. Signa. — Take a teaspoonful every half hour in water. In pain where opiates are not desirable. Sie J. Y. Smpsox. [380. Emulsion of Chloroform.'] R. Chloroformi f3j ; Pulveris Tragacanthae gr. v; Pulveris Sacchari, Syrupi Orgeat, (vel Syrupi Amygdalae, U. S. P.) f Aquae, aa f ^ss. Misce secundum artem. This emulsion makes an admirable means of producing an extemporaneous solution of chloroform ; it may be diluted to any proportion required, and yet by a little gentle agitation is easily suspended. The flavor makes it a delightful addi- tion to other mixtures. Iseael J. GtEahame. 381. Mixture of Magnesia, Assafetida, and Laudanum. R. Magnesia? Carbonatis 5ss: Tincturae Assafoetidae gtt. lx. Tincturae Opii gtt. xx ; Sacchari 5j ; Aquae destillatae fij. Fiat mistura. Signa. — Twenty-five drops may be given to an infant of two to four weeks old. In flatulent colic, diarrhoea, etc. This preparation was strongly recommended by the late Dr. Dewees, and it is dow much employed in this city under the name of Devjees's Carminative. If the calcined magnesia be used, it unites with the resin of the assafetida, forms an almost solid mass at the bottom of NAKCOTICS. 149 the vessel, and defeats the object of the prescription, conse- quently the carbonate should be preferred. 382. Carminative for Infants. R. Magnesia? Carbonatis 9j ; Vini Opii gtt. xv; ■ Syrupi Acacia? f3iij ; Aqua? Cinnamomi f 5v. Misce. Signa. — Shake well before using. Dose, ten drops-for a child three days old. Used to relieve colicky pains, and to correct the green alvine discharges of infants. 383. Tincture of Hemp. R. Extracti Cannabis purificati, gr. xxiv; Alcoholis f Jj. Fiat solutio. Signa. — Take three to ten drops every two hours. The above is the formula of Dr. O'Shaughnessy, of Calcutta, who has had much experience with the gunjah or Indian hemp. In cholera, he gave ten drops every half hour to check the vomiting ; in tetanus, a drachm of the tincture, with the same interval, until the paroxysms ceased, or catalepsy was induced ; and in acute rheumatism, twenty drops until symptoms of intoxication were manifested. 384. Alcoholic Solution of Oil of Bitter Almonds. R. Olei Amygdala? Amara? n^xx ; Alcoholis f 3iij. Fiat solutio. Signa. — Take ten drops four times daily. Used in neuralgia, tic douloureux, and other painful com- plaints. Hobn. Clysters and Suppositories. 385. Laudanum Enema. R. Tinctura? Opii gtt. 1 ; Infusi Lini Compositi f^ij. Fiat enema. ■ Used for obstinate vomiting, chronic dysentery, and pain ful affections of the pelvic viscera. 150 NAKCOTICS. [This formula is the one generally adopted for the laudanum enema, sometimes substituting starch water for the flaxseed tea. It has always seemed to the editor that this was a very bad method of using a most valuable remedy. The purpose of the opiate enema being to act as an anodyne by its absorp- tion, the object will be best attained by having as little as possible of the diluent to relieve the irritant impression of the alcoholic solution, and to have this diluent of such material as will be most readily taken up by the bowel ; and instead of two ounces of flaxseed tea, I have always been in the habit of ordering about three fluidrachms of warm water. The syringe should work accurately, as any air forced through it into the rectum causes tenesmus, and very often the ejection of the anodyne.] It is generally supposed that three times the quantity of a medicine may be thrown into the rectum that may be taken into the stomach. As regards opium, however, we believe it to be too much, particularly in children. Indeed, it is an un- settled point in therapeutics, whether remedies in relative doses, act more powerfully upon the rectum or upon the stomach. 386. Opium Suppository. R. Pulveris Opii gr. ij ; Saponis gr. iv. Misce bene. Signa. — Introduce into the rectum when a local anodyne is indicated. 387. Another Form. R. Olei Theobromee ^ss ; Pulveris Opii gr. xij. Liquefac cum leni calore. Misce, et fiant suppositoria xij. Signa. — One to be introduced into the bowel. This is a good form for securing the effects of opium, when the remedy cannot be borne by the mouth. S. W. Mitchell. 388. Suppository of Opium and Rhatany. R. Olei Theobromse ^ss; Extracti Krameme 9ij ; Pulveris Opii gr. v. Misce secundum artem, et fiant suppositoria x. Used in piles, relaxation or descent of the bowel, fissure of the anus, etc. J. Pancqast. NARCOTICS. 151 389. Suppository of Morphia. R. Olei Theobromas 3ss; Morphias Sulphatis gr. iij. Liquefac, et fiant suppositoria xij. The introduction of one of these into the bowel, every three or four hours, affords much relief in painful affections of the pelvic viscera, and, especially, in dysmenorrhoea, and cancer of the womb. Chordee can usually be controlled by the use of one at bedtime. They have also proved highly beneficial in arresting the pain attendant upon a threatened abortion. E. P. Thomas. 390. Suppository of Hemlock. R. Olei Theobromae 3j ; Extracti Conii gr. x. Misce, et fiat suppositorium. Used in cancer of the rectum, womb, or bladder. External Use of Narcotics. 391. Mixture of the Extract of Belladonna. R. Extracti Belladonnas, Glycerinae, aa 3j. Tere simul. Used for dilating the pupil in cataract, by rubbing around the eyebrow and on the temples. 392. Solution of Atropia. R. Atropiae gr. ij ; Acidi Acetici gtt. yj ; Aquae destillatas f§j. Fiat solutio. Signa. — Let a drop or two fall into the eye to dilate the pupil. This is equally efficacious in its action, and more elegant than the ordinary preparations of belladonna. It is also much more prompt, a healthy iris being acted upon in ten to twenty minutes. W. W. Cooper. Three minims of this solution, containing one-eightieth of a grain of atropia, may be considered equivalent in activity to one-third of a grain of the extract, or fifteen drops of the tinc- ture of belladonna, for internal administration. R. P. T. 152 NARCOTICS. [393. Solution of Sulphate of Atropia.] R. Atropine Sulphatis gr. i-ij ; Aquae destillatae fsj. Fiat solutio. Signa. — Apply one or two drops to the eye. For the relief of irritation of the conjunctiva or cornea, the weaker solution will answer; for active and prompt dilatation of the pupil, the stronger. This formula is preferable to those in which the alkaloid is extemporaneously dissolved in acetic or other acid, the latter form being often irritating and painful, whereas the solution of the salt is not. [394. Solution of the Extract of Calabar Bean.'] R. Extracti Physostigmae Alcoholici gr. j ; Aquae destillatae f'5j. Fiat solutio. Used as an application to the conjunctiva for its remark- able effect in contracting the pupil when dilated abnormally, whether from previous use of belladonna or otherwise. To be applied with a camel's-hair brush. T. Gr. Mop.tox. 395. Mixture of Opnum. Lime-water^ etc. R. Extracti Opii gr. j ; Liquoris Calcis, Olei Amygdalae Dulcis, aa f5Hj. Fiat mistura. Eecommended by Dr. Sibergundi, of Dorsten, in the treat- ment of sore nipples. It is to be applied on dossils of lint. 396. Dental Anaesthetic. R. Tincturae Aconiti Eadicis, Chloroformi purificati, Alcoholis, aa Oj ; Morphiae gr. vj. Misce. Signa. — Moisten two pledgets of cotton with the liquid, and apply to the gums for a minute or two, around the tooth. Employed to diminish the pain of extraction of teeth, and to deaden sensibility in the gums. Teft. To be used with caution on account of the aconite. NAKCOTICS. 153 397. Decoction of Stramonium in Milk. R. Stramonii Folii 3ij ; Lactis recentis Ojss. Coque ad Oj. Employed for gouty, rheumatic, and other painful swellings, by applying both the boiled leaves and the milk to the affected part. 398. Sedative Application. R. Extracti Belladonnas, 5jss ; Tincturse Opii r^xl. Tere simul, et adde — Chloroformi Yenalis 5j- Misce. Signa. — For local application. A portion of this mixture is to be smeared over the seat of pain in neuralgia, or other local painful affections. DlDAY. 399. Lotion of Atropia. R. Atropise gr. vj ; Acidi Acetici gtt. x ; Grlycerinse f3iij- Misce. Forty or fifty drops are to be applied by friction over the track of the nerve, three times daily, in facial neuralgia. 400. Anodyne Plaster. R. Emplastri Plumbi 3ij ; Liquefac lento igne, et adde gradatim — Pulveris Opii, Pulveris Camphorae, aa Jss. Fiat emplastrum. Used for enlarged joints, rheumatism, and local pains. The officinal "Emplastrum Opii" is employed for the same pur- poses. 401. Plaster of Opium and Camphor. R. Pulveris Opii 9ij ; Camphoras 3ss ; Picis Burgundicae 3j ; Emplastri Plumbi q. s. ut flat emplastrum ivxvj. This plaster is highly recommended in neuralgia. Gkaves. 154 NARCOTICS. 402. Plaster of Opium and Belladonna. R. Extracti Opii gr. xv; Extracti Belladonnas 3j ; Glycerines tt^xx vel q. s. Misce. Signa. — Spread on adhesive plaster 3x4 inches, leaving an adhesive margin all ronnd. This is an excellent application to the face for toothache, or to other parts for the relief of neuralgia. 403. Liniment of Belladonna, Bitter Almond Water, etc. R. Extracti Belladonnas 9ij ; Aquas Amygdalae Arnaras f^ij. Tere simul, dein adde — ^Etheris fgj. Misce. Signa. — Eub the liniment on the affected part, and apply a flannel moistened with it, the whole to be covered with a piece of oiled silk. Useful in neuralgia, in gouty and rheumatic pains, and for gathered breasts. Eakque. 404. Camphor and Chloroform Liniment. R. Camphorae 3jss; Chloroformi Yenalis 3ij ; Olei Olivae §ij. Fiat linimentum. Useful in rheumatic and neuralgic affections. W. B. Price. 405. Chloroform and Soap Liniment. R. Linimenti Saponis f^ij ; Chloroformi Yenalis f3j. Misce. Employed like the preceding in rheumatic pains. The quantity of chloroform may be advantageously increased. Tuson. NAECOTICS. 155 406. Compound Chloroform and Aconite Liniment. R. Olei Eicini 3ij ; Chloroformi Venalis, Spiritus Ammonias, Tincturae Aconiti Eadicis, aa f 3ij ; Linimenti Saponis f^j. Misce. Employed in rheumatic pains, bruises, etc. W. Peocter, Je. CLASS XII ANTISPASMODICS. Antispasmodics are those medicines which allay spasm, and compose the irregular actions of the nervous system. Some of the most powerful of them are derived from the class of Narcotics. Pills, etc. 407. Pills of Assafetida and Soap. B. Assafcetidse 3j ; Saponis gr. x. Contunde in massam, et fiant pilulae xx. Signa. — Two of these pills may be taken for a dose. Used in hysteria, and as a mild laxative. 408. Pills of Castor and Succinic Acid. R. Castor ei 3j; Acidi Succinici 5ss; Extracti Gentianae q. s. ut fiant pilulae xxiv. Signa. — Dose, three pills night and morning. In hysteria. 409. Pills of Musk, Camphor, &c. R. Moschi 9ss; ' Camphorae 9j ; Ammoniaci 9ij ; Opii gr. iv. Misce, et fiant pilulae singulae gr. iv pendentes. Signa. — One pill to be given every three hours. In nervous diseases. M. A. Richaeds. ANTISPASMODICS. 157 410. Pills of Valerianate of Zinc. R. Zinci Valerianatis gr. xij ; Confectionis Kosae q. s. ut fiat massa in pilulas xij divi- denda. Signa. — Give one pill every three hours. Used in neuralgia, epilepsy, and anomalous nervous affec- tions. Mixtures, Etc. 411. Mush Mixture. R. Moschi optimi 3ij ; Sacchari 5j ; Pulveris Acaciae 3j ; Aquae destillatae f3vj. Fiat mistura et adde — Tincturae Opii Camphoratae f Iss ; Tincturae Valerianae Ammoniatae f 3j- Misce. Signa. — A teaspoonful three or four times a day. For children in pertussis. 412. Mixture of Sumbul and Valerian. R. Tincturae Sumbuli (Bad. Sumb. oij ad Alcoholis Oj), Tincturae Valerianae, aa fsj. Misce. Signa. — Dose, a teaspoonful every two hours, in sweetened water. The sumbul, or musk-root of Asia, has attracted some at- tention in Europe as a mild stimulant, suited to the low forms of fever, controlling the nervous symptoms that arise during convalescence from fevers. It has been prescribed also for the relief of cramps, spasms, and hysteria. Granville. 418. Mixture of Assafetida, Castor, and Ammonia. R. Tincturae Assafoetidae, Tincturae Castor ei, aa f £j ; Spiritds Ammoniae Aromatici f 3j. Misce. Signa. — A teaspoonful may be taken in a glass of sweetened water for a dose. 158 ANTISPASMODICS. 414. Hoffman's Anodyne and Laudanum. R. Spiritus JEtheris Compositi f3iij ; Tincturae Opii gtt. lxxx ; Aquas Cinnamomi f svj. Fiat mistura. Signa. — A tablespoonful every two hours. Given in hysteria, and to quiet restlessness and morbid vigilance. 415. Mixture of Assafetida, Valerian, and Castor. R. Assafoetidas 3j ; Aquas Menthae Piperitae fliij. Fiat mistura, et adde — Tincturae Valerianae Ammoniatae f 3ij ; Tincturae Castorei f 3iij ; ^Etheris f 3j. Signa. — A tablespoonful for a dose, largely diluted, every second hour. In hysteria. 416. Mixture of Nitric Acid. ' R. Acidi Mtrici "ixxxij ; Syrupi f ^iijss ; Tincturae Cardamomi Compositas fiiss. Misce. Signa. — Dose, half a teaspoonful every three hours. Prescribed in pertussis, the quantity to be augmented in proportion to the age of the patient, and the severity of the paroxysms. H. Holmes. 417. Mixture of Cimicifuga. R. Extract! Cimicifugas Fluidi, Syrupi ACaciae, aa f£ss ; Aquae Amygdalae Amarae f^iij. Misce. Signa. — A teaspoonful every three hours. Black snakeroot is a remedy of much value in the treatment of diseases of the nervous system, and especially in chorea and hooping-cough. ANTISPASMODICS. 159 418. Assafetida Enema. R. Tincture Assafoetidse f 5ij ; Mucilaginis Ulmi f3vj. Misce pro enemate. Administered in hysteria, spasmodic colic, etc. A third, or even one-half of this quantity may be safely and beneficially given to a young child in convulsions. CLASS XIII. SIALAGOGUES. Those medicines which increase the salivary secretion are denominated Sialagogues. In forming these into a class in this place, we trespass on the arrangement of Dr. Chapman, but merely from a motive of convenience ; for we agree with him that such a class would be better expunged from the Materia Medica, at the same time that it appears necessary to introduce it here, in order to place the mercurial prepara- tions in stronger relief than could otherwise be done. 419. Powders of Calomel. R. Hydrargyri Chloridi Mitis gr. ij ; Sacchari lactis 9j. Terre simul et divide in pulveres viij. Signa. — Take one powder every two hours. When the practitioner wishes to obtain the alterative effects of mercury, it is better to administer very small doses, at short intervals. A larger quantity would probably act upon the liver, and secondarily, upon the bowels. 420. Pills of Corrosive Sublimate, B. Hydrargyri Chloridi Corrosivi gr. vijss; Amyli 3j ; Syrupi Acacise q. s. ut fiant pilulae Ix. Signa. — Give one pill three times a day. Prescribed in constitutional syphilitic affections. Trousseau. SIALAGOGUES. 161 421. Dupuytrerfs Antisypliilitic Pills. R. Hydrargyri Chloridi Corrosivi gr. ss; Extracti Cinchona gr. x ; Extracti Opii gr. ss. Fiant pi]ula3 ij. Signa. — The two pills may be taken, one in the morning, and the other at night ; "but as each contains a quarter of a grain of corrosive sublimate, their action must be Yery closely watched. M. Dupuytren was partial to these pills in the treatment of syphilis. He thought the opium and cinchona promoted and beneficially modified the action of the sublimate. 422. Pills of Corrosive Sublimate and Hemlock. B. Hydrargyri Chloridi Corrosivi gr. vj; Extracti Conii 3j ; Pulveris Conii q. s. ut fiat massa, in pilulas xlviij dividenda. Signa.— Give one pill three times a day. Used in lues venerea. The effect of the mercurial preparations upon children is sometimes very serious and even fatal. So powerful upon them is the action of this medicine, that a profuse or even gentle salivation will sometimes produce mortification and de- struction of the jaw, cheek, and lip. This, however, does not often happen ; but to avoid it, the gums should be frequently and carefully examined. It is, nevertheless, a fact, that a disease precisely similar in all its features occasionally attacks children who are badly clothed and fed, though no mercury has been given to them. B. Ellis. 423. Pills of Iodide of Mercury. B. Hydrargyri Iodidi Viridis gr. v; Confectionis Rosse q. s. ut fiant pilulse xxx. Signa. — Each pill will contain the sixth of a grain, which may be given three times a day. Double the quantity (two pills) is sometimes administered at first, but care should be taken not to push the remedy too far. 11 162 SIALAGOGUES. 424. Compound Pills of Iodide of Mercury. R. Hydrargyri Iodidi Yiridis, Lactucarii, aa 3ss; Extracti Opii gr. ix ; Eesinse Gruaiaci 3j. Misce, et fiant pilulas xxxvj. Signa. — Take one pill three times daily. Highly recommended both in primary and secondary syphi- lis, the treatment being continued until mercurialization appears. Eicokd. 425. Pills of Calomel, Camphor, and Opium. R. Hydrargyri Chloridi Mitis, Camphorse, aa 9j ; Pulveris Opii gr. x ; Syrupi q. s. ut fiant pilulss xx. Signa.- — One to be taken morning, noon, and night, when calomel by itself causes purging. B. Ellis. 426. Pills of Blue Mass. R. Pilulas Hydrargyri 3ss. Divide in pilulas x. Signa. — One to be taken night and morning. When used as thus prescribed, blue -mass is one of our best alteratives in the treatment of syphilitic disease, and all other complaints where the mercurial impression is indicated. If eight or ten grains be taken at bedtime, one or two eva- cuations of the bowels will occur during the next day. 427. Pills of the Red Oxide of Mercury. R. Hydrargyri Oxidi Eubri gr. j ; Pulveris Opii gr. j ; Olei Caryophylli gtt. ij. Fiant pilulae iij, Signa. — One pill every night for a week. In venereal cases. This preparation, in a stronger formula, was used and highly recommended by the celebrated John Hunter ; but from its harshness it is now generally superseded by milder medicines. SIALAGOGUES. 163 428. Solution of Cyanide of Mercury. R. Hydrargyri Cyanidi gr. viij ; Aquas Oj. Fiat solutio. Signa. — A teaspoonful of the solution, containing one-six- teenth of a grain of the cyanuret, may be given morning, noon, and night, watching its effects. This is the Liquor Anti-syphilitique of Chaussier, who pre- fers it to corrosive sublimate, on account of its greater solubility and more speedy action. 429. Powder of Mercury and Chalk with Ipecacuanha. E. Hydrargyri cum Creta 9j ; Pulveris Ipecacuanhas Bss. Fiant chartulas vj. Signa.—One night and morning in syrup. Commended by Dr. Paris, in dyspepsia, in which the biliary secretion is impaired. He prefers it under these circumstances to every other form of mercury. 430. Masticatory of Pellitory and Mastich. R. Pulveris Pyrethri, Mastiches, aa 5j. Signa. — Let these be mixed together by a moderate applica- tion of heat ; then divide the mass into two equal parts. One of these lumps may be chewed at pleasure. Used in toothache and paralytic affections of the tongue. Walthee. CLASS XIV t o isr i c s. Toxics are those medicines which impart strength to the system, without subjecting it to any preternatural excitement during their operation. They stimulate, however, in a second- ary manner, by gradually increasing the force of the circula- tion, and by restoring the digestive and secretory functions to a more healthy state. Considerable perseverance is often necessary in giving any one of this class a fair trial; and when one fails, we may often resort with success to another. Much also may sometimes be gained by alternating them. It is a well-known fact that some medicines possessed of tonic properties, in small or ordinary doses, have the singular power, when administered more freely, of producing such changes in the economy as to render them applicable to the cure of intermittent disease. The numerous remedies of this class, and their varied modes of exhibition, render it advisa- ble, in a work of this kind, to have some mode of distinguish- ing them from ordinary tonics. For convenience of reference, therefore, two sub-classes have been made, viz., 1. Of Anti- Inter mittents, and 2. Of Ordinary Tonics. Sub-Class I.— ANTI-INTERMITTENTS. At the head of this class stand, confessedly, Peruvian Bark and its numerous preparations. Powders and Pills. 431. Povjder of Peruvian Bark. R. Pulveris Cinchonas Rubras Ij. Signa. — A teaspoonful to be taken every hour in port wine, water, or milk, during the intermission of fever. TONICS. 165 Some practitioners suspend the bark till within a few hours of the expected paroxysm; and others administer it during the hot stage of the disease. It is better to commence imme- diately after the paroxysm has ended, and give a dose every hour, until the expected period of its return; and to continue it in smaller quantities for several days. If the bark should purge when given alone, a little opium may be added ; when it oppresses the stomach, cloves, as in the next prescription ; if costiveness should follow, rhubarb, or sulphate of magnesia. 432. Powder of Peruvian Bark, Cloves, and Cream of Tartar. R. Pulveris Cinchonas Eubrse, Potassse Bitartratis, aa Ij ; Pulveris Caryophylli 3j. Misce. Signa. — Dose, a teaspoonful in syrup every second hour. This compound will sometimes succeed in arresting mias- matic disease when the bark alone fails. 433. Powder of Peruvian Bark, Virginia Snakeroot, and Soda. R. Pulveris Cinchonas ^ss: Pulveris Serpentarise 3j ; Sodas Bicarbonatis 9ij. Divide in chartulas iv. Signa. — One to be given every two hours. In obstinate intermittents. 434. Powder of Prussian Blue and Guaiac. R. Ferri Ferrocyanidi, Pulveris Gruaiaci Kesinae, aa 5j. Misce, et divide in chartulas xij. Signa. — One three times a day. In obstinate intermittents. 435. Pills of Sulphate of Quinia. R. Quinias Sulphatis gr. xx; Acidi Sulphurici Aromatici "ixv. " Drop the acid into the sulphate of quinia on a tile or slab, and triturate it with a bone spatula until it assumes a pilular consistence; then divide rapidly into the required 166 topics. number of pills." Made in this way a three-grain pill is not inconveniently large. E. Paeeish. In prescribing quinia in the apyrexia of intermittents, and especially in that of neuralgia, it is often necessary to increase the dose beyond the officinal formula, which is one grain in each pill. For example, three, four, or five grains may be requisite in those cases in which the neuralgic paroxysms are violent, and the intermission short ; and this quantity must be repeated every two or three hours, or even every hour. The principal inconveniences arising from the free exhibition of quinia are a painful sense of fulness, noise, and dizziness of the head, constriction of the chest, and purging. The latter may be checked by accompanying each pill with a few drops of laudanum, or by a tablespoonful of the simple aqueous infusion of camphor. If the affection of the head or chest becomes severe, the medicine must be suspended or diminished in quantity. 436. Pills of Quinia, Opium, and Black Pepper. R. Quinige Sulphatis gr. xx; Pulveris Opii gr. ij ; Oleoresinse Piperis Rv; Syrupi Acacias q. s. ut flat massa in pilulas xx dividenda. Signa. — Give two pills every hour in the morning of an ex- pected chill. In ordinary intermittents the sulphate of quinia retains the first rank for promptness and efficiency in arresting the par- oxysm ; but in chronic cases it frequently fails. In the treat- ment of the latter, the present prescription will prove an excellent agent. 437. Powders of Sulphate of Quinia and Tartar Emetic. B. Quinige Sulphatis gr. x; Antimonii et Potassas Tartratis gr. iij. Misce, et divide in partes yj aequales. Signa. — Grive one powder every two hours. This preparation is commended as having been successful in intermittent fever, when quinia alone produced no favor- able result. It causes vomiting and purging, and prevents the recurrence of the paroxysm. It should be given during the intermission. Gola. TONICS. 167 438. Pills of Sulphate of Quinia and Carbonate of Ammonia. R. Quinias Sulphatis gr. xij ; Ammonias Carbonatis gr. xxiv ; Syrupi Acacias q. s. Fiant pilulas xij. Signa. — One every hour, beginning six hours before the ex- pected paroxysm. These pills are large, but they will act when quinia alone proves unavailing. 439. Pills of Chinoidine. R. Chinoidini 9ij ; Extracti Grentianas gr. x. Tere simul, et fiant pilulas xl. Signa. — Take two pills every three hours. Dr. Gremmil has tried chinoidine for two or three years, and has found it an effectual substitute for quinia. He gives two grains every three hours during the intermission, until twelve to sixteen pills are taken, and on the sixth, thirteenth, and twentieth days, eight or ten pills in the same way. J. M. GrEMMILL. 440. Pills of Sulphate of Cinchonia. R. .Cinchonias Sulphatis 3ss ; Pulveris Acacias gr. x ; Acidi Sulphurici Aromatici ^Lx. Fiat massa, et divide in pilulas xx. Signa. — Take two pills every hour in the apyrexia of inter- mittent fever, until eight are taken. Experiments made in several public institutions of Phila- delphia prove the sulphate of cinchonia to be an efficient sub- stitute for quinia, in a somewhat larger dose. 441. Pills of Sulphate of Quinidia. R. Quinidias Sulphatis 3j ; Pulveris Acacias gr. xij ; Mellis q. s. ut fiat massa in pilulas lx dividenda. Signa. — Take two pills every hour, until eight are taken. Used in intermittent disease in the same way as the sul- phate of quinia. There seems to be little difference in the strength and effect of the two salts. 168 toxics. 442. Po wde rs of Sa lie ine. R. Salicini gr. xxiv ; Sacchari 9iv. Misce, et divide in partes viij asquales. Signa. — A powder to be taken three times a day. Salicine possesses decided anti-intermittent powers. It has to be used, however, in doses double or treble those of the sulphate of quinia. Keombholz. 443. Pills of Arsenic and Opium. R. Acidi Arseniosi gr. j ; Pulveris Opii gr. iv; Saponis gr. xj. Fiat massa, et divide in pilulas xvj. Signa. — Give one pill three times a day, and increase gradu- ally, according to circumstances, watching the effect. In intermittent fever, and local diseases of an intermittent character. Marcus. 444. Pills of Sulphate of Copper and Extract of Bar J:. R. Cupri Sulphatis gr. iv; Extracti Cinchonas gr. xxxij ; Syrupi q. s. ut flat massa, in pilulas xvj dividenda. Signa. — One to be taken three times a day. In obstinate intermittents. Chapmax. 445. Pills of Sulphate of Copper and Opium. R. Cupri Sulphatis gr. iij ; Pulveris Opii gr. iv ; Syrupi Acacias q. s. ut flat massa, in pilulas xij dividenda. Signa. — Give one pill every three hours in obstinate intermit- tents. This combination is sometimes serviceable, when quinia fails. Chap^iax. 446. Pills of Sulphate of Bebeerine. R. Bebeerinas Sulphatis 5j; Pulveris Acacias gr. xv; Mellis q. s. Fiat massa, et divide in pilulas xxx. Signa. — Give one pill every two hours. TONICS. 169 This article has attracted attention in Edinburgh and Paris, and the experiments, thus far reported, warrant a more ex- tended trial of its powers, in intermittent diseases, such as periodical headache and neuralgic affections. Decoctions, Solutions, and Mixtures. 447. Decoction of Cinchona. R. Cinchonae Kubras contusae ^j ; Aquae bullientis Oj. Coque per sextam horae partem, et adde — Serpentariae 3ss; Aurantii Corticis 3ij- Macera per horam dimidiam in vase leviter clauso et cola. Signa, — Dose, a wineglassful. If the bark is boiled longer than ten minutes, it deposits extractive and resinous matter, becomes paler, and is less effi- cient. The last ingredients are directed to be infused, because their aromatic properties would be dissipated by decoction. 448. Peruvian Bark Mixture. R. Decocti Cinchonas Eubrae f Zvj ; Tincturae Cinchonae Compositae f ^j ; Acidi Sulphurici Aromatici ^ix. Misce. Signa. — A tablespoonful may be taken every two hours. Used in obstinate intermittents. 449. Solution of the Sulphate of Quinia. R. Quiniae Sulphatis gr. viij ; Acidi Sulphurici Aromatici gtt. x ; Aquae foj. Fiat solutio. A teaspoonful contains one grain of the salt. The strength of this solution can be increased by adding three drops of elixir of vitriol for every two grains of the salt. 450. Mixture of Sulphate of Quinia. R. Quiniae Sulphatis gr. xx; Acidi Sulphurici Diluti n^xx ; Sacchari 3ij ; Aquae Cinnamomi f^ijss. Misce. Signa. — A teaspoonful for a dose, every hour during the apy- rexia of intermittents. 170 TONICS. By the addition of sulphuric acid, a super-sulphate of quinia is formed, which is soluble in the aqueous menstruum. [451. Another, for Children^ R. QuiniaB Sulphatis gr. vj ; Syrupi Acacias, Aquae Cinnamomi, aa f3yj. Misce. Signa. — Shake well before using. Give a teaspoonful for a dose. This combination has the advantage of the taste being less developed, the salt being only in suspension and not •in solu- tion, each dose containing half a grain. 452. Sulphate of Quinia in Syrup. R. Quinias Sulphatis gr. xvj ; Syrupi Zingiberis £Jij, Misce. Signa. — A teaspoonful to be given every hour during the apyrexia. The French physicians employ a wine and tincture of quinia, which, however, are not superior to the compound used in this country. Both in Europe and America, and especially in Italy, the dose is carried to a much greater extent than we have directed. Eight, ten, fifteen, twenty, and even thirty grains have been given by the Italians, without manifest injury and with successful results. Such doses, however, are seldom ad- missible in this country ; and a cure can generally be accom- plished by giving sixteen or twenty grains in twenty-four hours, repeated in half doses for three or four successive days. S. G. Morton. 453. Mixture of Ferrocyanate of Quinia. R. Quiniee Ferrocyanatis gr. iv; Alcoholis f3j. Solve et adde — Aquas Camphorae f3vij. Misce. This preparation is said to be more active than the sul- phate, whence it should be given in less doses ; a teaspoonful of the solution (which will contain half a grain of the salt) may be taken every hour or two hours, according to circum- stances. Pills of the ferrocyanate of quinia are prepared with simple mucilage, and administered like the sulphate. TONICS. 171 454:. Mixture of Sulphate of Quinia and Tartaric Acid's R. Quinige Sulphatis gr. vj; Acidi Tartarici gr. iij ; . Syrupi flj. Misce. Signa. — Dose, a teaspoonful. The advantages of this preparation are increased solubility and diminished bitterness of the quinine salt. Casorati. 455. Mixture of Sulphate of Quinidia and Tannic Acid. R. Quinidiae Sulphatis gr. xvj ; Acidi Sulphurici Aromatici ^Ixyj ; Aquas fljss; Acidi Tannici gr. iv ; Syrupi Aurantii Corticis flss. Fiat mistura. Signa. — A dessert-spoonful every three hours. From experiments made in the Pennsylvania Hospital and other public institutions, the sulphate of quinidia has been found as active as the corresponding salt of quinia, and may be substituted for it in most cases, without disadvantage. 456. Mixture of Sulphate of Cinchonia and Iron. R. Cinchonige Sulphatis gr. xxxij ; Tincturge Ferri Chloridi f^ss; Aquas fjiijss,, Misce. Signa. — A teaspoonful every three hours in sweetened water. This mixture has been prescribed with great benefit at the Philadelphia Dispensary in cases of intermittent fever attended with anaemia. . Gr. Martin". Prepared with syrup instead of water, the taste is much less nauseous, and also less persistent. 457. Mixture of Tincture of Bark and Citrate of Potassa. R. Succi Limonis f Ijss : Potassae Carbonatis 5j ; Tincturge Cinchonas f 3j ; Aquae Cinnamomi f Jiij, Misce. Signa. — A tablespoonful every two hours. Used to promote insensible perspiration while taking the bark. B. Ellis. 172 toxics. 458. Mixture of Fluid Extract of Bark and Cardamom. R. Extracti Cinchonas Fluidi f 3j ; Tincturse Cardamomi Composite f 51J ; Syrupi Zingiberis f Jj. Misce. Signa. — A dessert-spoonful for a dose. Used both, as a tonic, and as an anti-intermittent remedy. 459. Mixture of Fowler's Solution and Elixir of Opium. R. Liquoris Potassas Arsenitis f 3j ; Tincture Opii Deodoratge "Ixxx; Aquas Cinnamomi f^iv. Fiat mistura. Signa. — A tablespoonful for an adult, a teaspoonful for a child ; to be administered every two or three hours, during the apyrexia of intermittents, watching the effect. 460. Enema of Quinia and Morphia. R. Quinias Sulphatis gr. xv; Morphias Sulphatis gr. J; Mucilaginis Amyli f sij. Misce pro enemate. When administered in this way, quinia exerts an imme- diate and powerful effect on miasmatic diseases. It is par- ticularly indicated in cases of intermittent or remittent fever, attended with irritability of the stomach. [461. Solution of Quinia for Hypodermic Injection^] R. Quinias Sulphatis 3j ; Acidi Sulphurici diluti f 3ss ; Aquas destillatae f5vijss. Fiat solutio. Thirty minims of this solution, containing 3 J grains, in- jected beneath the skin, will give the effects of about 7 J grains by the mouth, and may be repeated as required with- out danger from nausea, or the inconvenience resulting from the possible ejection when given in the ordinary way. (See the section on Hypodermic Injection.) TONICS. 173 Sub-Class IL— ORDINARY TONICS. Powders and Pills. 462. Powders of Columbo, Ginger, etc. R. Pulveris Calumba3, Ferri Subcarbonatis, Pulveris Rhei, Pulveris Zingiberis, aa 3j- Misce, et fiant pulveres xij. Signa. — One to be taken three times a day, in molasses. Used in dyspepsia, angemia, and chlorosis. 463. Powders of Iron reduced by Hydrogen. R. Ferri Redacti 3ss; Sacchari 3j- Misce, et divide in pulveres xij. Signa. — Take one powder three times a day in syrup or molasses. This has been much used in angemia and chlorosis. It is one of the best preparations of iron. 464. Powders of Ipecacuanha, Iron, and Mercury. R. Ferri Subcarbonatis gr. xlviij; Pulveris Ipecacuanhse gr. vj ; Hydrargyri cum Creta gr. xij. Misce, et divide in pulveres vj. Signa. — Take one powder twice a day. Used with decidedly good effect in chlorosis. S. Ashwell, 465. Powder of Columbo and Potassio-tartrate of Iron, R. Ferri et Potassse Tartratis 9ij ; Pulveris Calumbse 3ss. Fiant pulveres iv. Signa. — One every three or four hours, in syrup. An excellent tonic, used in dyspepsia and chlorosis. 174 TOXICS. 4:66. Powders of Subnitrate of Bismuth. R. Bismuthi Subnitratis 5ss; Sacchari 3j. Misce, et divide in pulveres x. Signa. — Give one powder three times daily. Used in gastrodynia, chronic vomiting, and chronic diar- rhoea. Kecamier. [467. Powder of Bismuth and Iron.] R. Ferri Eedacti gr. vj ; Bismnthi Subnitratis gr. xxiv. Misce, et divide in chartulas xij. Signa. — One powder every three or four hours. In the atonic diarrhoea of tuberculosis, or following cholera infantum. 468. Pills of YalMs Mass. R, Pilulae Ferri Carbonatis 3j ; Ferri Subcarbonatis q. -s. ut fiant pilulae. xx. Signa. — A pill to be taken morning, noon, and night. This is one of the best of the chalybeate preparations, and may be used whenever it is desirable to introduce iron into the system. 469. Pills of Lactate of Iron, R. Ferri Lactatis 3j ; Extracti Grlycyrrhizae 3ss; Mellis q. s. ut flat massa in pilulas xl divideuda, Signa. — Take one pill three times daily. Used in dyspepsia, anaemia, chlorosis, etc, This salt is well suited to the diseases of childhood, as its taste is not unpleasant, and it can be administered in the form of a syrup. Trousseau. 470. Pills of Ammoniated Copper. R. Cupri Ammoniati 9j ; Confectionis Kosae q. s. ut fiant pilulae xl. Signa. — One to be taken morning and evening. Prescribed in epilepsy. TONICS. 175 471. Pills of Iron and Strychnia. R. Strychniae gr. j ; Ferri Eedacti gr. xxx ; Mucilaginis Tragacanthas, q. s. ut fiat massa in pilulas xxx dividenda. Signa. — One pill three times daily. This is an efficient combination, serviceable in the treat- ment of chlorosis and dyspepsia. 472. Pills of Extract of Ignatia, Aloes, and Opium. R. Extracti Ignatise Alcoholici gr. viij ; Pulveris Aloes purificatae gr. vj ; Pulveris Opii gr. ij ; Mucilaginis Acacias q. s. ut fiat massa in pilulas xxiv . dividenda. Signa. — One pill three times daily. Eecommended in dyspepsia. If attended with constipation, the opium can be omitted. E. P. Thomas. 473. Compound Pills of Ammoniated Iron. R. Ferri Ammoniati, Gralbani, aa 3j ; Assafcetidae 3ij ; Castorei 9j ; Tincturae Valerianae q. s. Contunde in massam, et divide in pilulas singulas gr. iij pen- dentes. Signa. — Let two pills be given night and morning. Used successfully in a variety of chronic nervous diseases, hysteria, and anomalous nervous symptoms. Berends. 474. Pills of Citrate of Iron and Quinia. R. Ferri et Quinise Citratis 3ss; Pulveris Acaciee gr. x ; Mellis despumati q. s. Fiat massa et divide in pilulas xx. Signa. — Take one pill every four hours. This preparation has been much employed in hemicrania, chlorosis, and anaemia. It is one of the most valuable tonics. 176 TONICS. 475. Pills of Sulphate of Iron and Quinia. R. Quinias Sulphatis gr. xij ; Ferri Sulphatis exsiccatae gr. xxiy ; Pulveris Opii gr. iij ; Syrupi q. s. Misce, et flant pilulae xij. Signa. — Take two pills three times daily. Used in chlorosis and anasmia. Kiekby. 476. Pills of Valleys Mass and Quinia. R. Pilulas Ferri Carbonatis 3ss ; ■ Quiniae Sulphatis gr. x. Fiat raassa, et divide in pilulas xv. Signa. — One pill every four hours. Given in hemicrania, and as a tonic in anasmia. Thomas. [477. Bretonneau 's Iron Pill] R. Ferri Eedacti gr. cxxv; Quinias Sulphatis gr. vijss ; Extracti Cinchonas gr. xxviij ; Pulveris Zingiberis gr. vij ; Extracti Khei Compositi gr. xxviij ; Aloe's Socotrinas gr. iv ; Syrupi q. s. Misce, et divide in pilulas 1. Signa, — Take three or four pills daily. In anaemia with constipation. [478. Pills of Podophyllin, Aloes, and Iron.] R. Podophyllin gr. iij ; Aloe's Socotrinas, Extracti Nucis Vomicae, aa gr. xv ; Ferri Sulphatis Exsiccati gr. xlv; Olei Caryophyllas gtt. x ; Syrupi Acacias q. s. Misce, et divide in pilulas xxx. Signa. — Take one pill immediately before each meal. An efficient tonic laxative pill, in indigestion with costive- ness. TONICS. 177 479. Pills of Iron, Bed Pepper, &c, R. Pulveris Aloes Socotrinas, Ferri Sulphatis exsiccatas, aa dj ; Mastiches gr. x ; Pulveris Capsici dj ; Syrupi q. s. Fiat massa in pilulas xx dividenda. Signa. — Take one pill every four hours. In chlorosis. Copland. 480. Mitchell's Tonic Pills. R. Extracti Quassias 3ij ; Extracti Conii gr. x ; Ferri Subcarbonatis gr. x ; Liquoris Potassas Arsenitis gtt. x. Fiat massa in pilulas xl dividenda. Signa. — Take one pill three times daily. Used in dyspepsia. J. K. Mitchell. 481. Pills of Nitrate of Silver. R. Argenti Mtratis gr. iv; Avenas Farinas gr. iv ; Syrupi q. s. Fiat massa, et divide in pilulas xij. Signa. — Take one pill every three hours. Given in epilepsy, gastrodynia, chronic gastritis, and obsti* nate vomiting. 482. Compound Pills of Nitrate of Silver. R. Argenti Nitratis gr. v ; Pulveris Opii 9ss ; Pulveris Camphorse, Pulveris Myristicas, aa Bj ; Mucilaginis Acacias q. s. ut fiat massa, et divide in pilu- las xx. Signa. — Dose, a pill morning and evening. In chorea and epilepsy. 12 178 TONICS. 483. Pills of Iodide of Potassium and Manganese. R. Potassii Iodidi, Manganesii Sulphatis exsiccatse, aa 3j ; Mellis q. s. Fiat massa in pilulas xxx dividenda. Signa. — To be kept in a well- stopped bottle. Take one pill morning and night. The salts of manganese have recently been introduced as substitutes for the corresponding preparations of iron. Hannon. 484. Pills of Iron and Gentian. R. Ferri Eedacti 9j ; Extracti Grentianas 9ij. Fiat massa et divide in pilulas xx. Signa. — Take one pill three times a day. An excellent combination for ansemic conditions of the system. 485. Pills of the Sulphate of Iron and Quassia. R. Ferri Sulphatis 3j; Extracti Quassias 3j- Fiat massa et divide in pilulas xl. Signa. — One to be taken morning, noon, and night. In dyspepsia, etc. 486. Pills of Oxide of Zinc. R. Zinci Oxidi 9ij ; Confectionis Kosse q. s. ut riant pilulse x. Signa. — One three or four times a day. In epilepsy, chorea, etc. Dr. Chapman speaks favorably of this medicine, and recom- mends us to begin with the above dose, and gradually to increase it. 487. Pills of Lactate of Zinc. R. Zinci Lactatis gr. xxx ; Syrupi Acacise q. s. ut flat massa in pilulas xx dividenda. Signa. — Take one pill three times daily. Lactate of zinc has recently been introduced as an efficient agent in the treatment of diseases of the nervous system. It is particularly recommended in epilepsy. Hekpin. tonics. 179 488. Electuary of Cinchona, Bust of Iron, etc. R. Pulveris Cinchonas Kubras, Ferri Subcarbonatis, aa 3j ; Mellis q. s. ut fiat electuarium. Signa. — To be made into pills of the ordinary size, of which four may be taken three times a day. 489. Pills of the Oxide of Silver. R. Argenti Oxidi gr. vj; Pulveris Acacias gr. vj ; Aquas q. s. ut fiat massa in pilulas xij dividenda. Signa. — Take one pill three times daily. Used with much success in pyrosis. Also highly recom- mended in menorrhagia. B. Lane. [490. Pills of Pepsin and Aloes.'] R. Pepsinas Porci gr. xxxij; Ext. Aloe's Barbadensis gr. viij ; Glycerinas q. s. Fiat massa, et divide in pilulas viij. Signa. — Take one every day at dinner. Useful in indigestion with costiveness. Tanner. [491. Pills of Arsenic, Nux Vomica, and Iron .] R. Acidi Arseniosi gr. j ; Podophyllin gr. iij ; Extracti Nucis Yomicas gr. xv ; Ferri redacti gr. xlv ; Olei Caryophylli gtt. x; Syrupi Acacias q. s. Misce, et divide in pilulas xxx. Signa. — Take one pill after each meal. In anemia, with hepatic torpor and asthenia. [492. Pills of Strychnia and Bismuth."] R. Strychnias gr. j; Bismuthi Subnitratis 3jss; Syrupi Acacias q. s. Misce, et divide in pilulas xx. Signa. — One before each meal. In dyspepsia with pyrosis and nausea. 180 TONICS. Infusions and Decoctions. 493. Infusion of Sage, Boneset, and Cascarilla. R. Salvias, Eupatorii, aa 3ss; Cascarillas 3j ; Aquas bullientis Oj. Digere per horas duas et cola. Signa. — Dose, a wineglassful every three or four hours. Used in hectic fever. 494. Infusion of Columbo and Ginger. R. Calumbas contusas Ij ; Zingiberis contusas 5ij ; Aquas bullientis Oj. Fiat infusum et cola. Signa. — Give a wineglassful every two hours. This infusion, freely used, is adapted to chronic diarrhoea. 495. Infusion of Columbo, Rhubarb, etc. R. Cari, Calumbae contusas, Ehei contusi, aa 9j ; Aquas ferventis f Jiv. Digere per horas duas, cola, et adde — Tincturas Rhei f 3j ; Syrupi Zingiberis f3ij. Misce. Signa. — Dose, a teaspoonful to a tablespoonful for children, according to their age. In diarrhoea. 496. Compound Infusion of Wild Cherry Bark. R. Pruni Yirginianas 3j ; Aurantii Corticis 3ij ; Aquas Oj. Macera per horas sex et cola. Signa. — A wineglassful may be taken every hour or two in consumptive cases, asthma, etc. TONICS. 181 497. Compound Infusion of Virginia Snakeroot. R. Serpentarias, Contrayervas contuses, aa 3v; Aquas bullientis Oj. Digere per horas daas, cola, et adde — Tinctures Serpentarias f oij. Misce. Signa. — Dose, a tablespoonful. Used in the convalescence of typhoid fever and other dis- eases of an asthenic type. Guy's Hospital Phakm. 498. Compound Infusion of Quassia. R. Quassias, Serpentarias, Aurantii Corticis, aa 3ss ; Aquas bullientis, Oij. Fiat infusum et cola. Signa. — A teacupful to be taken cold, three times a day. 499. Infusion of Chamomile and Orange Peel. R. Anthemidis 3ss; Aurantii Amari Corticis 3ij ; Aquas Oj. Macera per horas decern et cola. Signa. — Dose, a wineglassful four times a day. The infusion of chamomile made with cold, is in general more grateful to the patient than when made with boiling water. The same remark applies to infusions generally, and they are also less liable to ferment. B. Ellis. 500. Infusion of Hops. R. Humuli §j; Aquas ferventis Oj. Digere per horas duas et exprime. Signa. — A wineglassful may be taken three or four times a day. In dyspepsia. 501. Compound Infusion of Gentian. R. Gentianas contusae 3ss; Aurantii Dulcis Corticis, Cardamomi, aa 3j ; Aquas bullientis Oj. Fiat infusum. 182 toxics. Gentian is an excellent bitter. The above preparation is given in wineglassful doses, in debility of the digestive or- gans, &c. [502. Tonic Laxative Infusion.'] R. Gentianas contusas §j; Ehei Contusi 3ij ; Sodas Bicarbonatis 3jss; Zingiberis contusas 3ss. Misce. Signa. — Put into 1J pint of boiling water and boil to a pint, strain, and take a wineglassful at each meal. Very useful in dyspepsia with acidity and costiveness. 503. Compound Decoction of Angustura Bark. R. Angusturas contusas Iss; Aquae fixij. Coque ad fsyj, et adde — Tincturas Cinnamomi f 3ij ; Syrupi Aurantii Corticis f^j. Misce. Signa. — Dose, a tablespoonful every three hours. This may be used in all cases in which a tonic and mild stimulant remedy is indicated. Berends. 504. Decoction of Dogwood Baric. R. Cornus Floridas contusas §j; Aquas Oj. Coque per horam dimidiam, et cola. Signa. — A wineglassful may be given every hour as a substi- tute for Peruvian bark in intermittents, or as an ordinary tonic every two hours. 505. Decoction of Peruvian Bark and Valerian. R. Cinchonas Kubras contusas Ij; Aquas Ojss. Coque per sextam horas partem, cola, et adjice — Valerianae contusas 3j. Macera per horam unam et cola. Signa. — Dose, a wineglassful four times daily. This was a favorite prescription with the late Dr. Joseph Parrish, in rheumatic and nervous headache and hemicrania. TONICS. 183 506. Infusion of Acorns. R. Pulveris Glandis Quercus torrefactae §j; Aquae bullientis Oj. Fiat infusum. Signa. — Three or four teacupfuls may be taken during the day, and be augmented according to circumstances. The above is a favorite remedy with the Germans. "It is one of the most successful in mesenteric atrophy, commencing rachitis, glandular swellings, asthma, and cough. Continued for a long time, it is one of the most powerful means we pos- sess for destroying the scrofulous disposition." — Hufeland, Treatise on Scrofula, p. 215. Mixture s, Tinctures, etc. 507. Griffith's Myrrh Mixture. R. Myrrhae £j ; Sacchari 3ij ; Potassae Carbonatis gr. xxv. Tere simul, et adde gradatim — Aquae Kosae f^vijss; Spiritiis Lavandulae f^ss. Dein adde — Ferri Sulphatis crystallizati, in pulverem contriti, 9j. Fiat mistura. Signa. — Dose, a tablespoonful every four hours. This preparation was formerly much used as a tonic in phthisis. 508. Mixture containing Protoxide of Iron. R. Ferri Sulphatis 3j; Magnesiae gr. x; Sacchari 3j ; Aquae Cinnamomi f^viij. Misce. Signa. — Take a tablespoonful every three hours. An efficient tonic in phthisis. Donovan. 18-i TONICS. 509. Mixture of Ammonio- Tartrate of Iron. R. Ferri et Ammonia Tartratis 3ij; Syrupi Aurantii Corticis f ^ij ; Tincturae Cardamomi f^j ; Aquae f^v. Fiat mistura. Signa. — A dessert -spoonful every four hours. Used iu chlorosis and debility. The ammonio-tartrate is one of the most valuable of the ferruginous preparations. Its pleasant taste and ready solubility render it available in the treatment of the diseases of childhood. 510. Mixture of Sulphate of Iron and Elixir of Vitriol. R. Ferri Sulphatis gr. iv; Acidi Sulphurici Aromatici r^xx ; Aquae destillatae f^j. Fiat mistura. Signa. — A teaspoonful to be taken three times a day in a wineglassful of water. 511. Mixture of Sulphuric Acid. R. Acidi Sulphurici Diluti f^iv; Syrupi Aurantii Corticis f^jss ; Aquas Cinnamomi f 3j. Fiat mistura. Signa. — Take a teaspoonful three times a day in a wineglass- ful of water. Used in anaemia and debility. Sir James Clark. 512. Mixture of Sulphuric and Nitric Acids. R. Acidi Sulphurici Diluti f5ij ; Acidi Nitrici Diluti f 3j ; Syrupi fgij ; Aquae Menthae Piperitae f^iv. Misce. Signa. — Take a dessert-spoonful in water every three hours. Dr. W. J. Anderson and several other English practitioners have found the acid treatment effectual in arresting the watery discharges in diarrhoea, cholera morbus, and cholera. In the last disease, the doses should be larger, and more frequently administered. tonics. 185 513. Vinegar Draught. B. Aceti f Ij ; Tincture Cardamomi Composite, Syrupi, aa f 3ss ; Aquae f 5x. Misce. Signa. — To be taken in such portions as the stomach can bear. Used in sick headache. 514. Wine of Gentian and Orange Peel. E. Pulveris Gentianae, Aurantii Corticis Dulcis, aa Iss ; Yini Portensis Oj. Macera per dies tres, et cola. Signa. — Give a wineglassful two or three times a day. In dyspepsia. 515. Mixture of Cinchona, Valerian, etc. R. Tincturae Cinchonas, Tincturae Valeriana, aa f 3j ; Tincturae Cardamomi Composite f 3ij ; Aquas Menthae Piperitae f^iv. Fiat Mistura. Signa. — A tablespoonful may be given every third hour. This is especially designed as a tonic in nervous tempera- ments. 516. Elixir of Aloes, Zedoary, Gentian, etc. B. Pulveris Aloe's Socotrinae j|j ; Pulveris Zedoariae, Pulveris Gentianae, Croci, Pulveris Rhei, Agarici, aa 3j ; Spiritus Yini Gallici Oij. Macera per dies septem, cola, et adde — Syrupi f 3ij. Misce. Signa. — Dose, a tablespoonful three times a day, in water. This is the celebrated Baume de Yie, or Elixir of Life. It is a powerful tonic, and one of the most effectual febrifuge medicines. In intermittents, especially, it is justly celebrated. 186 toxics. [517. Elixir of Cinchona."] R. Quinias Sulphatis gr. xxv ; Quinidias Sulphatis, Cinchonias Sulphatis, aa gr. x ; Sacchari Ixx ; Olei Anisi, Olei Foeniculi, aa gtt. ij ; Olei Cinnamomi Zeylandici gtt. vj ; Olei Cari gtt. j ; Olei Aurantii "Ixl; Spiritiis Curagoas fivj ; Alcoholis deodorati, Aquas, Aquas Eosas, aa Oj ; Caramel f 3iij. Misce secundum artem. Dissolve the sulphates in the alcohol ; rub together the oils and sugar, and dissolve them in the water and rosewater, and add the alcoholic solution and Curacoa ; lastly, add a solution of carmine in aqua ammonias, just sufficient to color properly, and then the caramel. Mix thoroughly, and filter through paper until perfectly clear. Israel J. Grahame. [518. Ferrated Elixir of Cinchona] is made as the last, except that instead of the carmine solu- tion there is to be added, before filtration, one hundred and twenty-eight grains of ammonio-citrate of iron to each pint of the fluid. * I. J. Grahame. The advantage of these elixirs of cinchona is in having the active principles of the cinchona bark in the form of its salts, without the extractive matter, tannic acid, etc. They form very beautiful and palatable forms for administration. [519. Elixir of Bismuth^ R. Bismuthi Ammonio Citratis 3ij gr. xvj. Aquas destillatas f jfij ; Aquas Eosas f.5jss; Alcoholis deodorata f §iij ; Syrupi fgij ; Aquas Ammonias q. s. ; Olei Aurantii n^x ; Olei Cinnamomi Zeylandici, Olei Caryophylli, aa gtt. j ; Olei Anisi gtt. ij. Misce. TONICS. 187 Dissolve the oils in f Ijss of the alcohol, add the syrup, and agitate the mixture well. Dissolve the bismuth salt in the distilled water and rosewater, adding sufficient aqua ammonias to produce a perfect solution. Add this to the first mixture, and lastly the remainder of the alcohol ; let it stand a short time, and filter until perfectly clear and bright ; if not so, add about f3ij more of alcohol. An elegant method of administering bismuth; each tea- spoonful containing about two grains of the salt. I. J. Grahame.' [520. Mixture of BismuthJ] B. Bismuthi Subnitratis gr. cc; Pulveris Tragacanthse gr. xxv ; Misce, et adde secundum artem, Syrupi Orgeat, (vel Syrupi Amygdalae U. S. P.) Aquae, aa f^ij ; Elixir Bismuthi (Formula 519), Alcoholis, aa f^ss. Misce. Signa. — A teaspoonful for a dose. Each dose of this delightful preparation contains five grains of the salt of bismuth ; with a little agitation it is suspended thoroughly, and the taste entirely covered. I. J. GRAHAME. 521. Mixture of Nitrate of Silver. R. Argenti Nitratis gr. j ; Aquas destillatae f^ij ; Sacchari 3ij. Fiat mistura. Signa. — A teaspoonful every two hours. Used in the diarrhoea of newly-weaned infants. This is accompanied by the occasional injection of one-fourth of a grain of the salt in mucilage. Hirsch. 188 TONICS. 522. Fowler's Solution and Potassio- Tartrate of Iron. R. Ferri et Potassas Tartratis gr. xvj ; Aquas Cinnamomi f Jj. Solve, et adcle — Syrupi fgj ; Liquoris Potassas Arsenitis n^xxxij. Fiat mistura. Signa. — A teaspoonful three times daily, for a child one or two years old. Used in eczema infantile, and other skin diseases of early life. Ekasmus Wilson. 523. Mixture of Muriated Tincture of Iron. B. Tincturse Ferri Chloridi f3ij ; Glycerinas f 3xiv. Misce. Signa. — Dose, a teaspoonful every three hours. This old and valuable tincture still retains the first rank among the chalybeates. Its ferruginous taste is so much modified by combination with glycerine as to remove the chief objection to its use. Eecommended as an astringent in diarrhoea, and other ex- hausting discharges; and as a tonic, by Bell and Yelpeau, in erysipelas. 524. Mixture of Ammonio- Citrate of Iron. B. Ferri et Ammonias Citratis 5ij i Syrupi Limonis f 3j ; Aquas f^iij. Fiat mistura. Signa. — Take a teaspoonful every four hours. Employed in amenorrhcea and chlorosis. It may be given, also, in less quantity, in the anaemia of childhood. 525. Mixture containing Peracetate of Iron. R. Tincturas Ferri Chloridi f 3iij ; Liquoris Ammonias Acetatis f Jiij ; Syrupi Aurantii Corticis foj ; Acidi Acetici nix. Misce. Signa. — A dessert-spoonful four times daily. TONICS. 189 Prescribed as a ferruginous tonic for children, and for anaemia in adults. It has slight diuretic properties. J. F. Meigs. 526. Mixture of Perchhride of Iron and Nitric Acid. R. Tincturae Ferri Chloridi, Aeidi Nitrici Diluti, aa fjj ; Syrupi Zingiberis f 3xiv ; Aquas Menthas Yiridis fsiv. Misce. Signa. — A tablespoonful every four hours. Eecommended as an astringent and tonic in phthisis. E. Bennett. 557. Steel Wine. R. Ferri et Potassae Tartratis Jss; Yini Xerici Oj. Solve, et cola. Eecommended as a uniform and effectual substitute for the officinal vinum ferri. The dose is a tablespoonful, containing about four grains of the potassio-tartrate of iron. J. C. POOLEY. [528. Mixture of Arsenic and Iron!] R. Liquoris Potassae Arsenitis f 3j ; Ferri Ammonio Citratis 3U 5 Elixir Cinchonas f^iij. Misce. Signa. — A dessert-spoonful after each meal. In anaemia with neuralgic tendency, or as a tonic after ma* larial affections. 529. Mixture of JBestucheffe's Tincture and Valerian. R. Spiritus Ferri Chlorati iEtherei (Ph. Borus.) f 3ij ; Aquae Cinnamomi, Syrupi Aurantii Corticis, aa f ^j ; Infusi Valerianae f 3v. Misce. Signa. — Shake well, and take a tablespoonful every two hours. " Bestucheffe's Nervine Tincture," or "Lamotte's Golden Drops," as the preparation is variously called, is a favorite in Germany in the treatment of chlorosis, anaemia, and hysteria. SOBERNHEIM, 190 TOXICS. 530. Mixture of Pernitrate of Iron. R. Liquoris Ferri Nitratis f3j; Syrupi f 3ij ; Aquae f 3 v. Fiat mistura. Signa. — Give a teaspoonful every three hours. This preparation is very serviceable in all forms of diar- rhoea, but more especially in chronic mucous diarrhoea, hem- orrhage from the bowels, uterine hemorrhage, &c. Neligan. 531. Mixture of Pyrophosphate of Iron. R. Ferri Pyrophosphatis 3j 5 Syrupi, _ Aquas Cinnamomi, aa f^ij. Misce. Signa. — Take a teaspoonful an hour after each meal. M. Robiquet called attention to the superior advantages of the pyrophosphate over other salts of iron. Its taste is less unpleasant, it is freely soluble in water, it agrees well with the stomach, and is easily assimilated. 532. Mixture of Iodide of Iron and Manganese. R. Liquoris Ferri et Manganesiae Iodidi f §ss ; Glycerinae f^jss. Misce. Signa. — Take a teaspoonful every three hours. This is used as a tonic, alterative, and emmenagogue. The salts of manganese are beginning to attract attention. The formulas for their preparation, by Prof. Procter, will be found in the American Journal of Pharmacy, vol. xxv. p. 198. [533. Syrup of Iron, Quinia, and Strychnia.] R. Ferri Phosphatis precipitate 3j? gr. iv; Quinias gr. xxxij ; Strychnia? gr. j ; Acidi Phosphorici diluti q. s.; Sacchari pulveris q. s. ; Aquas ad fjiv; Olei Aurantii gtt. v. Misce secundum artem. The iron, quinia, and strychnia should be carefully dis- TONICS. 191 solved in the dilute phosphoric acid, the water added, and sugar sufficient to make a syrup by agitation or gentle heat. The syrup contains in each fluidrachm 2 grains of the iron salt, 1 of quinia, and ^ of a grain of strychnia. In anasmia with nervous debility. T. A. Lancaster. 534. E.lixir of Pepsine. B. Pepsini (Boudault) 3jss; Aquas f3yjss; Yini Xerici f 3xijss ; Alcoholis f 5iij ; Sacchari 3j. Solve et cola. jSigna. — A tablespoonful, containing fifteen grains of pepsine, is administered immediately after each meal, in cases of indigestion. Mialhe. CLASS XY. ALTEEATIYES. Alteratives are medicines that re-establish the healthy functions of the animal economy, without producing any active evacuation. This class of remedies, therefore, embraces nume- rous preparations which produce a slow but decided effect on the various secreting organs, sometimes without any sensible increase of the secretions themselves, but in other instances obviously augmenting or magnifying them. Such is the action of minute doses of mercury, iodine, and other sub- stances upon the glandular apparatus. These medicines are generally classed with stimulants and tonics, some of them with narcotics, and others have been placed with those pre- parations to which they seem most allied when given in an overdose — sialagogues, for example. Without attempting to investigate this question farther than regards practical con- venience, we proceed in this place to indicate the more active and important Alteratives; merely premising the familiar truth, that medicines of almost every class of the materia medica become alteratives by being administered in very small doses at intervals of a few hours. Pills and Powders. 535. Calomel Pills. R. Hydrargyri Chloridi Mitis gr. ij ; Confectionis Eosse q. s. ut fiant pilulas xij. Signa. — One may be taken every two hours. The use of calomel in minute doses has become very gene- ral, and deservedly so. In the hepatic and intestinal com- plaints of children it is productive of the happiest results when carefully managed. ALTERATIVES. 193 In infants, for example, the sixteenth or the eighth of a grain, repeated every hour or two hours, according to age and circumstances, will often check diarrhoea, cholera infantum, and dysentery, which have resisted every other treatment. If the discharges are attended by pain and tenesmus, small doses of powdered opium or laudanum may be added ; but, as a general rule, the anodyne had better be given by injection. The preparation called blue pill (pilulse hydrargyri) is indi- cated in similar conditions, and is especially beneficial when- ever an alterative is called for. A grain given at bedtime, or even a grain in divided portions through the day, will often produce the desired effect. Hence its extensive use in chronic and obscure derangements of the digestive organs, especially of the stomach and liver ; in the whole class of syphilitic affections ; glandular enlargements, etc. In like manner, all the mercurial preparations mentioned under the head of Sialagog-ues, become alteratives by cau- tious administration in doses more or less minute, and espe- cially when they are given in conjunction with the prepara- tions of sarsaparilla. 536. Pills of Calomel, Quinia, and Opium. R. Hydrargyri Chloridi Mitis gr. vj ; Pulveris Opii gr. iij ; Quiniee Sulphatis gr. xij ; Syrupi q. s. ut fiat massa in pilulas xij dividenda. Signa. — One night and morning. 537. Pills of Blue Mass, Quinia, and Aloes. R. Pilulse Hydrargyri, Quiniae Sulphatis, Pulveris Aloes Socotrinse, aa gr. xij ; Syrupi Ehei q. s. ut fiant pilulas xij. Signa. — One three times a day. Either of the above prescriptions is adapted to the condition that follows bilious intermittent, or remittent fever. They may be denominated tonic alteratives. 538. Pills of Bed Iodide of Mercury. B. Hydrargyri Iodidi Eubri gr. ss ; Extracti Glycyrrhizse gr. viij. Misce, et divide in pilulas viij. Signa. — Two in the morning and two at night ; dose to be gradually and cautiously augmented. 13 194 ALTERATIVES. 539. Corrosive Sublimate Pills. R. Hydrargyri Chloridi Corrosivi gr. j. Solve in aqua destillata, dein adde — Micas Panis, Sacchari, aa gr. x vel q. s. ut fiant pilulas xx. Signa. — Take one pill every four hours as an alterative. DZONDI. 540. Pills of the Arseniate of Iron. R. Ferri Arseniatis gr. iij ; Lupulinas 3j- Fiat massa, et divide in pilulas xlviij. Signa. — Give one pill night and morning. Prescribed by Dr. Biett in scrofulous, cancerous, and her- petic diseases. Arsenic is a powerful alterative, and. should be administered with the utmost circumspection. 541. Asiatic Pills. R. Acidi Arseniosi gr. j ; Piperis gr. xij. Tere simul in pulverem subtilissimum, et adde — ■ Pulveris Acacias gr. ij ; Extracti gentianas q. s. Misce, et divide in pilulas xxiv. Signa. — Take one pill morning and night. Much used by Biett for tuberculous lepra. Par. Codex. 542. Iodide of Arsenic and Hemlock Pills. R. Arsenici Iodidi gr. j ; Extracti Conii 9ij. Fiat massa, et divide in pilulas xvj. Signa. — Take one pill morning and night. Given in lepra, impetigo, and cancerous disease. 543. Pills of Iodide of Silver, etc. R. Argenti Iodidi, Potassas Mtratis, aa gr. x. Tere simul in pulverem subtilissimum, dein adde — Pulveris Glycyrrhizas 3ss ; Sacchari 9j ; Mucilaginis Acacise q. s. Fiant pilulas xl. Signa. — Take one pill three times daily. ALTERATIVES. 195 Used successfully in the gastric affections of the Irish peasantry. C. Patterson. 544. Pills of Bromide of Iron. R. Ferri Bromidi gr. xij ; Confectionis Kosse gr. xviij. Misce, et riant pilulse xx. Signa. — Two pills to be taken in the morning, and two in the evening, or one three times a day. In hypertrophy of the heart and scrofulous affections. Dr. Kobert Dick strongly recommends the use of the bro- mide of iron in dyspeptics with strumous habits. 545. Pills of Calomel and Ox Gall. R. Hydrargyri Chloridi Mitis 9j ; Fellis Bovini inspissati gr. xv. Saponis gr. x, vel q. s. Fiat massa, in pilulas xx dividenda. Signa. — Take two pills at bedtime. These pills are alterative and deobstruent. 546. Burnt Sponge. R. Spongiae Ustse 3j ; Sacchari 9j. Misce, et divide in chartulas vj. Signa. — One three times a day, gradually augmenting the dose. In bronchocele. It is well known that iodine was first discovered in sea- weed and sponges ; and the latter having long had the repu- tation of being a cure for goitre, it was found that iodine was the active remedial agent. We give above a prescription for the use of sponge, as formerly in vogue, but now nearly superseded by the preparations of pure iodine. [547. Pills of Tar.] R. Picis Liquidse 3ij ; Pulveris Grlycyrrhizae q. s. Misce, et divide in pilulas lx. Signa. — Two pills to be taken thrice daily, and the dose gradually increased for an adult. In chronic eczema. McCall Anderson. 196 ALTEKATIVES. Tinctures, Mixtures, etc. 548. Preparations of Iodine. That iodine is one of the most powerful alteratives at pre- sent known, there can be no question. There are few diseases dependent upon or connected with morbid secretion of the glandular structures, that are not more or less modified by its use, while in others it acts as a direct curative agent. It is chiefly, however, in scrofulous, glandular, and cutaneous affections that it acts most beneficially, dispersing indurations of the glands, and restoring the secretions of the cutaneous and mucous apparatus ; whence its advantages in eruptive diseases, bronchitis, leucorrhoea, amenorrhoea, etc. It has been found to restore suppressed hemorrhoidal and catamenial discharges, and, when pushed too far, has even produced alarming hemor- rhage of the lungs, nose, and uterus. These facts should make the practitioner extremely cautious in its administra- tion, beginning with small doses, and watching their effects. Should it produce any of the inconveniences already men- tioned, or dizziness, nausea, purging, burning of the skin or swelling of the gums, it should be at once suspended, or given less frequently and in smaller doses. 549. Ethereal Tincture of Iodine. R. Iodinii gr. vj ; Athens fgij. Misce. Signa. — Dose, ten drops two or three times a day, largely diluted. Fifty drops contain one grain of iodine. Given in cutaneous and glandular diseases. Mag-endie. The author of Illustrations of Pulmonary Consumption strongly recommends this formula in catarrh, phthisis, etc. It has a powerful effect in glandular disease, and all affections of the mucous membranes. S. Gr. Morton". 550. Mixture of Iodide of Potassium and Sarsaparilla. R. Potassii Iodidi 9ij ; Aquae f Siij ; Sacchari 3J ; Extracti Sarsaparillas Fluidi f sss. Misce. Signa. — Dose, a tablespoonful three times daily. ALTEEATIVES. 197 This valuable combination may be used in scrofula, second- ary syphilis, and obstinate skin diseases. In fact, it may be given advantageously in most cases requiring an alterative. 551. Mixture of Tincture of Iodine. R. Tincturse Iodinii f 3j ; Mucilaginis Acaciae f^ij ; Aquae destillatse f 3yj. Fiat mistura. Signa. — A tablespoonful every two hours. Employed in cases of ulceration accompanied by purulent discharge from the meatus auditorius, and in the scrofulous diathesis. 552. Solution of Iodide of Iron. R. Ferri Iodidi 3j ; Aquae destillatge f *j ; Sacchari 3ij. Fiat solutio. Signa. — Dose, six to ten drops, morning, noon, and night, in a wineglassful of cold water. The officinal solution — "Syrupi Ferri Iodidi" — keeps much better than an aqueous solution of the pure salt, and is there- fore generally preferred. Ten to twenty drops are given, diluted with water. 553. LugoVs Solutions. Dr. Lugol, one of the first experimenters with iodine, an- nounced that its solubility in water could be increased to any desired extent by the addition of iodide of potassium. He devised three preparations of different strengths, viz : — 'No. 1. Or the solution for internal use, contains of iodine, 1 part ; iodide of potassium, 2 parts ; and water, 20 parts. No. 2. The rubefacient solution, contains of iodine, 1 part; iodide of potassium, 2 parts ; and water, 12 parts. No. 3. The caustic solution, contains of iodine, 1 part ; iodide of potassium, 1 part ; and water, 2 parts. The first of these has retained his name, and it alone should be dispensed upon a prescription calling for Lugol's solution. It is the compound iodine solution of the Pharmacopoeia, viz : — 198 ALTEKATIVES. R. Liquoris Iodinii Compositi flss. Signa. — Give ten drops, in sweetened water, three times a day. Used in goitre and scrofulous diseases. 554. Magendie's Anti- epileptic Iodine Solution. R. Potassii Iodidi 3iv ; Iodinii gr. ij ; Aquae Menthae Piperita f^vj. Fiat solutio. Signa. — Dose, a teaspoonful thrice daily. Used in epilepsy and catalepsy. 555. Mixture of Iodide of Potassium. R. Potassii Iodidi 3j; Syrupi Zingiberis f^j ; Aquas f3v. Fiat mistura. Signa. — Take a tablespoonful three times a day. Prescribed in secondary syphilis, lupus, and various cuta- neous diseases. 556. Mixture of Iodo-hydrar gyrate of Potassa. R. Potassii Iodidi gr. iijss; Aquas destillatae f^j. Solve, dein adde — Hydrargyri Iodidi Eubri gr. ivss. The compound salt in this solution may be assumed at eight grains, although there is a small excess of the iodide of potas- sium. The dose is from two to five drops, containing from the thirtieth to the twelfth part of a grain, which may be re- peated three times a day, much diluted. De. Channixg. 557. Another Form. R. Hydrargyri Iodidi Yiridis gr. iij ; Potassii Iodidi 3ij ; Tincturae Gentianae Composite, Syrupi Sarsaparillae Compositi, aa Iij. Fiat mistura. Signa. — A teaspoonful three times daily. An invaluable remedy in secondary syphilis, and various ALTEKATTVES. 199 skin diseases, as well as an excellent alterative in follicular laryngitis and ulcerations of the epiglottis. Hokace Green. 558. Syrup of Ioduretted Biniodide of Mercury. R. Hydrargyri Iodidi Kubri gr. j ; Potassii Iodidi 5j ; Aquae f 5j ; Syrupi f|v. Misce. Signa. — A tablespoonful three times a day. This is employed like the two preceding formulas in second- ary syphilis and obstinate skin diseases. Hopital Saint Louis. 559. Iodine Waters. The physicians of Europe, and especially of Paris, have made extensive and salutary use of iodine waters, both inter- nally and externally. In these the iodine is very much diluted, and generally with the addition of more or less common salt. These waters are prepared on a large scale and with great precision by the pharmaceutists of Paris ; but they have been but partially introduced into this country. M. Magendie, however, gives formulas for some extemporaneous iodine waters, which may answer all the purposes of the more ela- borate preparations. The following is an example : — R. Potassii Iodidi gr. vj; Iodinii gr. j ; Aquae Oij. Fiat solutio. This solution is to be taken at meals, in place of common water. 560. Another Form. R. Syrupi Ferri Iodidi f5ss; Syrupi Acacias f^ij ; Aqaae Acidi Carbonici f^viij. Misce. Signa. — Take one-half at a draught, and then carefully cork the bottle to retain the gas in the remainder. DUPASQUIER. 200 ALTERATIVES. 561. Mixture of Donovan's Solution. R. Liquoris Arsenici et Hydrargyri Iodidi f3ij ; Syrupi Zingiberis f |ss ; Aquas f^iijss. Misce. Signa. — A dessert-spoonful an hour after each meal. Donovan. Donovan's solution affords a simple and efficient means of introducing into the system the three great alteratives. It has been found effectual in eradicating various chronic dis- eases, and especially the skin diseases of the scaly character, and venereal affections. 562. Solution of Bromine. R. Brominii f^ss; Syrupi Amygdalae f Jss ; Aquas f^ij. Misce. Signa. — Dose, five drops three times daily. Given in scrofula. Pourche. 563. Bibrorfs Antidote. R. Brominii 3v; Potassii Iodidi gr. iv ; Hydrargyri Chloridi Corrosivi gr. ij. Misce. Signa. — Take ten drops in a tablespoonful of wine or brandy. As these salts are but slowly soluble in bromine, there would be no objection, in cases of emergency, to dissolving them in a little water before the addition of the bromine. According to the experiments of Prof. Bibron, Prince Paul of Wurtemberg, Dr. W. A. Hammond, and others, this bro- mine mixture has proved a valuable antidote to the bite of the rattlesnake. The dose should be repeated every fifteen or twenty minutes, until relief is obtained. 564. Solution of Bromide of Potassium. R. Potassii Bromidi 9ij ; Syrupi Aurantii Corticis f 3j ; Aquas f^iij. Fiat mistura. Signa. — Give a tablespoonful three times a day. ALTEEATIVES. 201 The bromide of potassium is prescribed like the iodide, as an alterative, but is less efficacious. Huette and Thielmann recommend it in priapism, nymphomania, and satyriasis. Sir Charles Locock commends its efficiency in hysterical epilepsy, and directs it to be given in doses of five to ten grains, three times daily, for a week previous to, and during each menstrual period. 565. Solution of Bromine and Bromide of Potassium. R. Potassii Bromidi 3ij + 9ij; Aquas faij. Solve. Dein adjice — Brominii 3j ; Aquas ad f^iv. Misce. This is recommended as a convenient standard formula for the use of bromine. It can readily be diluted to any extent by the addition of water. Each fluidrachm contains five grains of the bromide of potassium and fifteen grains of bromine. Bromine is an excellent remedy in the treatment of hospital gangrene. J. Lawrence Smith. 566. Mixture of LugoVs and Fowler's Solutions. R. Liquoris Iodinii Compositi, Liquoris Potassse Arsenitis, aa f3ij. Misce. Signa. — Take ten drops three times daily. Used in chorea, psoriasis, pityriasis, and lepra. [567. Solution of Iodide and Bromide of Potassium^ R. Potassii Bromidi, Potassii Iodidi, aa 3ij ; Syrupi, _ Aquas Cinnamomi, aa f^iij. Misce. Signa. — A tablespoonful four times daily. In syphilitic neuralgia, nodes, etc.; also chronic rheu- matism. 202 ALTERATIVES. [568. Arsenic with Morphia and Cascarilla.'] B. Liquoris Potassae Arsenitis f3jss; Morphiae Hydrochloratis gr. J; Syrupi Limonis, Tincturae Cocci, aa f 3ss ; Infusae Cascarillae ad f ^xij. Misce. Signa. — A tablespoonful after each meal. In chronic eczema, attended with feeble digestion. McCall Anderson. [569. Solution of Arsenic and Iodine^ R. Liquoris Potassae Arsenitis trUxxx. Potassae Iodidi gr. xvj ; Iodinii gr. iv; Syrupi Aurantii f^ij. Misce. Signa. — A teaspoonful in a wineglass of water, thrice daily after meals. In chronic eczema. ISTeligan. 570. Pearson's Solution. R. Sodae Arseniatis gr. j ; Aquae f oj. Fiat solutio. Signa. — Dose, twenty drops three times a day. Used in the scaly and other skin diseases. It has less tendency than Fowler's solution to offend the stomach. An arseniate of ammonia was introduced by Biett, and employed by him in the same strength as the foregoing solu- tion, i. e., one grain to the fluidounce, and given in the dose of twenty drops. Its virtues are similar to those of Fowler's and Pearson's solutions. 571. Mixture of De Valangin's Solution and Iron. R. Liquoris Arsenici Chloridi (Lond.) f 5v ; Tincturae Ferri Chloridi f 3iij ; Aquae destillatae Oj. Misce. Signa. — Take forty drops three times daily, after meals. Arsenic in its various forms has long been held in repute ALTERATIVES. 203 as an alterative in lupus and cancerous affections. This com- bination secures both a tonic and an alterative effect. In strength, De Valangin's solution is intermediate between Pearson's and Fowler's solutions, jive fluidrachms containing nearly one grain. T. Hunt. 572. Mixture of Sal Ammoniac. R. Ammonias Muriatis 3ij ; Sacchari ^j ; Aquas Menthae Viridis fliijss. Fiat mistura. Signa. — A tablespoonful every three hours. The German writers describe sal ammoniac as an excellent alterative and resolvent. Dr. Watson, of London, recom- mends it in facial neuralgia; and Dr. Ebden, of Bengal, speaks highly of its use in nervous headache, clavus hystericus, and neuralgic affections generally. 573. Solution of Phosphate of Ammonia. R. Ammonias Phosphatis 3ss; Aquae destillatae f3vj. Fiat solutio. Signa. — A tablespoonful to be taken every four hours. This is a formula of Dr. Buckler, who recommends it in those cases of gout and rheumatism in which lithic acid is present in the urine ; as well as in all the modifications of those diseases, especially when they are associated with chronic thickening of the white tissues. 574. Cod-liver Oil {Oleum Morrhuse). This preparation, which is now divested in a great measure of its nauseous smell and taste, is given in doses of half an ounce, three or four times a clay. To children, a teaspoonful. The peculiar flavor which the best oil retains can be ren- dered less perceptible by introducing equal bulks of the oil and cherry-laurel water into a bottle, and shaking them well together. After subsidence the water is to be separated from the oil. It is of much service in all strumous affections, and in the chronic forms of gout and rheumatism. It may be taken alone, or in milk, or on the froth of porter. Some persons swallow it in coffee, in lemon-juice, or with some of the aro- matic waters. 204 ALTEKATIVES. Dr. Bradshaw recommends a weak infusion of flaxseed, flavored with lemon-peel, and sweetened to please the taste. He says: "I pour a small quantity of infusion into a glass, on which is added the oil, and again another small quantity of infusion upon it. In this manner, the dose may be swal- lowed, and will slip down without offending the palate, and generally is well retained even by irritable stomachs." The same author says : "Another mode has been successful when many have failed, and will be found equally valuable : It is the yelk of an egg beat up with boiling water and sugar, with which may be mixed a dessert-spoonful of brandy ; and on this, the dose may be given without producing that nausea so frequently experienced when conveyed by other vehicles." In the Editor's experience, the form of emulsion has proved to be one of the least satisfactory modes of exhibiting this article. He is in the habit of administering it in the pure state, directing the patient to chew a piece of orange peel or take a mintdrop before and after each draught ; or, what is equally effectual, to rinse the mouth and gargle the throat with vinegar, before and after the dose. 575. Mixture of Cod-liver Oil. R. Olei Morrhuas f Iss ; Liquoris Potassse gtt. xl ; Aquse Menthse Piperita f^ss. Misce, et fiat haustus. The draught to be washed down with a teaspoonful of lemon-juice, to liberate the oil on the stomach. Dunglisoi*, New Bern., 6th ed., p. 557. Perctval. 576. Another Fonn, for Children. R. Olei Morrhuas foj ; Yitellum unius ovi. Tere simul et adde gradatim — Syrupi Aurantii Corticis f ,lj ; Aquse Aurantii Florum f ^ijss. Fiat emulsio. Signa. — Give a tablespoonful three times daily. Used in scrofulous affections, and in rickets. Trousseau. ALTERATIVES. 205 577. Mixture of Cod-liver Oil and Quinia. R. Quiniae gr. xvj ; Alcoholis f3ij. Fiat solutio. Dein adde — Olei Morrhuse Oss. Solve cum leni calore. The quinia indicated in the prescription can be readily procured from a solution of the sulphate by the addition of ammonia. If the oil and quinia be gently heated in a water- bath, the solution takes place as the alcohol evaporates. Lyman. 578. Mixture of Cod-liver Oil and Iodine. R. Iodinii gr. jss; Olei Morrhuae f iv. Tere simul. Signa. — Dose, a tablespoonful three times a day. The quantity of iodine can be increased without materially changing the appearance of the solution. . Flelschmann. 579. Mixture of Corrosive Sublimate. R. Hydrargyri Chloridi Corrosivi gr. ij ; Aquae destillatas f %v ; Aquae Cinnamomi f 3ij ; m Syrupi f gj. Misce. Signa. — Dose, a tablespoonful thrice a day. This excellent alterative is often administered in compound syrup of sarsaparilla. It is better, however, to give it in a simpler form, to prevent any chemical change. It is particu- larly serviceable in the secondary forms of syphilis, and in syphilitic rheumatism. 580. Mixture of Nitro-muriatic Acid. R. Acidi Nitromuriatici f 3j ; Aquas f^viij. Misce, et adde — Spiritus ^Etheris ISTitrosi f3ij. Fiat mistura. Signa. — From twenty drops to half a teaspoonful to be given every three hours, in a wineglassful of sweetened water. 206 ALTERATIVES. This acid is also employed as a bath in hepatic derange- ments. For this purpose, put a teaspoonful of the acid into a quart of warm water, and apply it to the region of the liver night and morning, by means of a soft sponge. 581. Diluted Nitric Acid. R. Acidi Nitrici f3j ; Aquas Oij ; Sacchari j$j. Fiat mistura. Signa. — One- eighth of this quantity may be taken daily, in divided doses. In lues venerea. Nitric acid may be prescribed both as a tonic and an altera- tive in the above form. It is best taken through a quill, as the teeth suffer when it comes in contact with them. It some- times arrests the colliquative sweats of hectic fever when other remedies fail. Feeeiar, Med. Hi^. '582. Mixture of Hyposulphite of Soda. R. Sodas Hyposulphitis 5ij ; Infusi Quassias fsvj. Fiat solutio. Signa. — A tablespoonful three times daily. In France the hyposulphite is employed in chronic cuta- neous and scrofulous affections. It has likewise been used with advantage in rheumatism. This particular formula was resorted to successfully in an obstinate case of yeasty vomit- ing, accompanied with sarcinas ventriculi. R. JSTeale. 583. Artificial Harrowgate Water. R. Potassas Sulphatis cum Sulphure (Ed.) 5j j Potassas' Bitartratis 5ss ; Magnesias Sulphatis 3yj ; Aquas destillatas Oij. Solve. Signa. — One-half, taken in draughts, constitutes a full dose. The above ought to be taken in the morning, before break- fast, and be followed by a walk, to produce the desired effect. Duffix. ALTERATIVES. 207 584. FaWs Antacrid Tincture. R. Pulveris Guaiaci Kesinae *j ; Terebinthinas Canadensis %j ; Olei Sassafras f5ij ; Alcoholis f^viij. Misce, macera per dies septem, et cola; dein adde — Hydrargyri Chloridi Corrosivi 9j. Misce. Signa. — Take twenty drops in wine or sweetened water, night and morning. Dr. E. D. Fenner, of New Orleans, recommends this pre- paration in dysmenorrhoea and the consequent sterility. Dr. G. Emerson, of Philadelphia, has found it a valuable alterative in secondary syphilis. CLASS XYI ASTEINGESTS. Doctoe Cullen" describes astringents to be "such sub- stances as, applied to the human body, produce contraction and condensation in the soft solids, and thereby increase their density and force of cohesion." "And by the operation of this corrugating power," adds Dr. Murray, " either directly exerted on a part, or extended by sympathetic action, the morbid affections arising from a state of relaxation are sup- posed to be removed." In the use of this class of medicines a caution suggests itself, namely, that they should not be given to arrest evacua- tions that are critical, and designed by nature to relieve a plethoric state of the system, unless such evacuations exist to an alarming extent. Under this head are introduced, as a matter of convenience, many remedies which have the property of arresting morbid discharges, not from any inherent astringency, but from some alterative influence or stimulant impression upon the secret- ing organ from which the discharge takes place, as is the case with a large number of the remedies for diarrhoea which follow. Powders and Pills. 585. Compound Powder of Alum. R. Aluminis 9j ; Pulveris Kino gr. v. Fiant pulveres v. Signa. — One to be given every two hours. This compound, though much employed by some practi- tioners, contains substances which would be incompatible ASTRINGENTS. 209 with each other if given in solution. Used in menorrhagia, obstinate diarrhoea, etc. 586. Oxide of Silver and Aromatic Powder. R. Argenti Oxidi gr. xij ; Pulveris Aromatici gr. xxx. Misce, et fiant pulveres xij. Signa. — One powder every three hours. Sir James Eyre and Dr. Butler Lane extol highly the use of the oxide of silver in the various forms of passive hemor- rhage, and particularly in menorrhagia. 587. Powders of Sugar of Lead and Calomel. R. Hydrargyri Chloridi Mitis, Plumbi Acetatis, aa gr. j. Fiant pulveres iv. Signa. — Give one powder every three hours. In cholera infantum. The above dose is adapted to any period between ten and twenty months of age. T. D. Mitchell. 588. Powders of Sugar of Lead, Calomel, and Ipecacuanha. R. Hydrargyri Chloridi Mitis, Pulveris Ipecacuanhas, aa gr. ij ; Plumbi Acetatis gr. viij. Misce, et divide in pulveres viij. Signa. — Give one powder every three hours. Used in cholera infantum. The quantity of sugar of lead appears large, but experience proves that it may be given, both with safety and benefit, to a child from one to three years old. D. F. Condie. 589. Powders of Alum and Opium. R. Aluminis Jss j Pulveris Opii gr. iij. Fiant pulveres vj. Signa. — One to be taken every three hours. In diarrhoea. 14 210 ASTRINGENTS. 590. Powders of Suhnitrate of Bismuth and Magnesia. R. Bismuthi Subnitratis 3j ; Pulveris Acacise 3ss ; Magnesias 9j ; Misce, et divide in pulveres xij. Signa. — Give one powder every four hours. Used in the diarrhoea of phthisis. T. Thomson. [591. Powders of Calomel, Opium, and Bismuth.'] R. Hydrargyri Chloridi Mitis gr. j ; Pulveris Ipecacuanhas Compositi gr. iv ; Bismuthi Subnitratis gr. xviij. Misce, divide in chartulas xij. Signa. — Give one powder every two hours. In cholera infantum in its early stage, and in the inflamma- tory diarrhoea of children, to be followed after the diarrhoea is arrested by a mild laxative of castor oil or syrup of rhubarb. 592. Powders of Suhnitrate of Bismuth. R. Bismuthi Subnitratis gr. vj ; Sacchari gr. xij. Fiant pulveres vj. Signa. — Place a powder on the tongue of a child (one year old), three or four times daily. Used in the diarrhoea of children. Recamier, Trousseau. 593. Powders of Subcarhonate of Bismuth. R. Bismuthi Subcarbonatis gr. viij ; Sacchari Lactis gr. xvj. Fiant pulveres viij. Signa. — Administer one powder every three hours. Eecommended both for the mucous diarrhoea of children and for gastrodynia in adults, the properties of the subcar- bonate being analogous to those of the suhnitrate of bismuth. 594. Pills of Sugar of Lead and Calomel. R. Plumbi Acetatis 3ss ; Hydrargyri Chloridi Mitis gr. v ; Confectionis Rosas q. s. Fiant pilulas x. Signa. — One to be given every two hours. In hemorrhage, and especially in hasmatemesis. ASTKINGENTS. 211 595. Pills of Sugar of Lead and Opium. R. Plumbi Acetatis gr. xij ; Pulveris Opii gr. vj ; Confectionis Eosae q. s. ut fiat massa in pilulas vj divi- denda. Signa. — One to be taken every hour. Used in haemoptysis and other hemorrhages. It is also useful for checking the profuse perspiration in consumption. 596. Pills of Alum, Catechu, and Opium. R. Aluminis, Catechu, aa gr. vj ; Extracti Opii gr. j. Fiat massa, et divide in pilulas vj. Signa. — Give one pill every three hours. In passive hemorrhage, and in atonic mucous discharges. 597. Pills of Rhatany and Rhubarb. E. Extracti Krameriae 3j ; Extracti Ehei Alcoholici 9j ; Syrupi Zingiberis q. s. Fiat massa, et divide in pilulas xxx. Signa. — Take one pill every two hours. Prescribed in diarrhoea and chronic dysentery. 598. Pills of Creasote and Opium. R. Creasoti gtt. v ; Pulveris Opii gr. iij ; Pulveris Acaciae gr. vij. Tere simul, et divide in pilulas x. Signa. — One pill to be taken every three hours. Used in chronic diarrhoea, and in chronic bronchitis ; also employed for the relief of toothache, by pressing a pill into the cavity of a carious tooth. Blasius. [599. Pills of Creasote and Opium.] R. Creasoti 3 iij ; Opii Turcici 3ij ; Pulveris Capsici 3ij ; Pulveris Krameriae q. s. ut riant pilulae cxx. Signa. — Two pills every two hours till relieved. For the treatment of acute diarrhoea. J. Johnson. 212 ASTRINGENTS. 600. Pills of Kino and Opium. R. Pulveris Kino gr. xx; Pulveris Opii gr. ij ; Mucilaginis Acacise q. s. ut fiant pilulae vj. Signa. — Take one every four hours. In diarrhoea, pyrosis, &c. 601. Pills of Opium and Tannic Acid. R . Acidi Tannici gr. xx ; Pulveris Opii gr. v; Glycerinae q. s. ut fiat massa in pilulas x dividenda. Signa. — One pill every four hours. Glycerin is a good excipient for tannic acid, reducing it in bulk, and thus enabling the prescriber to combine it with other articles in pills of a moderate size^. This combination is very serviceable in affections of the bowels. 602. Pills of Tannin and Morphia. R. Acidi Tannici 9j ; Morphias Sulphatis gr. j ; Mucilaginis Acacias q. s. Divide in pilulas x. Signa. — One to be given every two hours. Blue mass may be added according to circumstances. In diarrhoea and dysentery. 603. Pills of Gallic Acid. R. Acidi Gallici 9j ; Extracti Gentianse gr. x. Fiat massa, in pilulas x dividenda. Signa. — Give one pill every three hours. Used in hematuria, and other hemorrhages. Gallic acid is also employed beneficially in pyrosis, and in the night-sweats of consumption. Mixtures, Infusions, etc. 604. Infusion of Matico. R. Piperis Angustifolii lj; Aque bullientis Oj. Macera per horas duas et cola. Signa. — Take a wineglassful every two hoars. ASTRINGENTS. 213 This "has been used to check the discharge in haemoptysis, haeruatemesis, and dysentery, as well as in leucorrhoea and gonorrhoea. 605. ParrisNs Camphor Mixture. R. Aquas Camphorae f^iij ; Spiritus Lavandulae Gompositi f 5j ; Sacchari 3j- Fiat mistura. Signa. — Give a tablespoonful every two hours in .diarrhoea and cholera morbus, adding ten drops of laudanum when there is much pain. Jos. Parrish. 606. Hope's Mixture. R. Aquae Camphorae fsiv; Acidi Mtrici ^liv; Tincturae Opii Rxl. Fiat mistura. Sig?ia. — Dose, a tablespoonful every two hours. In diarrhoea and dysentery. This is a well-known and very efficacious preparation analo-' gous to Hope's Mixture. If the nitric acid is added in larger proportion, it is liable to defeat the object of the prescription. The original formula contained a nuidrachm of nitrous acid, forty drops of laudanum, and eight fluidounces of camphor- water, and was given in doses of two fluidounces every three hours. Thos. Hope. 607. Chalk Mixture. R. Cretae Praeparatae 3jss ; Sacchari, Pulveris Acaciae, aa 3j ; Aquae destillatae f%iv ; Olei Cinnamomi ttlij ; Tincturae Opii ir^xl. Misce. Signa. — Dose, a tablespoonful every two hours. In diarrhoea and dysentery. When a strongly astringent mixture is desirable, we add to the above formula two fluidrachms of the tincture of kino, or the same quantity of the tincture of krameria, catechu, or nutgalls. 214 ASTRINGENTS. In the Children's Hospital of this city the prepared oyster- shell is substituted in this mixture for the chalk, with the addition of one fluidrachm of paregoric and three of tincture of rhatany, and given in teaspoonful doses every two or three hours. T. Hewson Bache. [608. Cholera Mixture^ B. Pulveris Aromatici 3iij; Tincturae Catechu f 3x ; Tincturae Cardamomi Composite f3vj; Tincturae Opii f 3j ; Misturas Cretas ad f Ixx. Misce. Signa. — For an adult two tablespoonfuls after each evacua- tion ; for a child seven years old a dessert-spoonful. In diarrhoea and cholera. — London Board of Health. 609. Jackson's Cholera Mixture. R. Spiritus Lavandulae Compositi, Spiritus CamphoraS, aa f^ss ; Tincturae Opii, Spiritus iEtheris Compositi, aa f 3ij. Misce. Signa. — Give twenty drops at short intervals in cholera mor- bus, and the early stages of cholera, to allay nausea and relieve pain. This prescription was frequently used in the cholera of 1832 by Professor Samuel Jackson with the most satisfactory results. 610. Decoction of Galls. R. Grallae contusas 3ij ; Aquas bullientis f 3x. Coque per sextam horae partem, et cola. A wineglassful of this is given every few minutes as an anti- dote, in cases of poisoning by any of the vegetable alkaloids, or by tartar emetic, sulphate of copper, sulphate of ziuc, etc. etc. It may be rendered more agreeable by the addi- tion of an aromatic, and some sugar, for administration in diarrhoea. Dose, a tablespoonful. ASTRINGENTS. 215 611. Mixture of Extract of Logwood and Catechu. R. Extracti Haematoxyli £iij ; Tincturae Catechu f 3ij ; Sacchari 3j ; Aquas f^vij. Misce. Signa. — A tablespoonful to be given once in three hours. In the advanced stages of diarrhoea and dysentery. 612. Blackberry Syrup with Aromatics. R. Syrupi Eubi f 3ij ; Spiritus Lavandulae Compositi f 3ij ; Aquae Cinnamomi f 3vj ; Aquae f^j. Misce. Signa.— Dose, a teaspoonful for a child. Employed with much benefit as a mild astringent and stimulant in cholera infantum, and the bowel complaints of children. E. P. Thomas. 613. Mixture of Ergot and Cinnamon. R. Extracti Ergotae Fluidi, Tincturae Cinnamomi, aa f^ss ; Syrupi fgj ; Aquae f ^ij. Misce. Signa. — Give a teaspoonful every three hours. Recommended in menorrhagia, and other hemorrhages. 614. Mixture of Geranium Maculatum. R. Extracti Geranii Fluidi {Thayer) f3yj ; Tincturae Cinnamomi f 3ij ; Syrupi Eosae Gallicae f^ij. Misce. Signa. — Take a dessert-spoonful every two hours. The geranium is the best of the indigenous astringent roots, and may be beneficially employed in cases of diarrhoea and chronic dysentery. Its freedom from unpleasant taste renders it particularly valuable in the diseases of childhood. 216 ASTRINGENTS. 615. Mixture of Tincture of Catechu and Laudanum. R. Tincturae Catechu f jfj ; Tincturae Opii f 3j ; Pulveris Acaciae 3ij ; Aquae Cinnamomi f Ivj. Misce. Signa. — A tablespoonful every two hours. In diarrhoea. 616. Creosote Mixture. R. Creasoti gtt. vj; Alcoholis f 3j ; Syrupi Amygdalae f 3ss ; Aquae f^ijss. Fiat mistura. Signa. — Dose, a dessert-spoonful diluted, every two or three hours. Used in hemorrhages and to allay sick stomach. [617. Another Form.] R. Creasoti nixvj ; Acidi Acetici Glacialis nixvj ; Olei Juniperi n^iij ; Alcoholis f 3ss ; Syrupi flj ; Aquae destillatae fixv. Misce. Signa. — Take one to two tablespoonfuls. In chronic diarrhoea, nausea of pregnancy, and some forms of dyspepsia. — British Pharmacopoeia. 618. Alcoholic Solution of Creosote. R. Creasoti, Olei Caryophylli, aa gtt. j ; Alcoholis f3j. Misce. A drop or two of this solution dropped into the cavity of an aching tooth, is said to afford immediate relief. [619. Mixture of Nitrate of Silver^ R. Argenti Nitratis gr. j ; Syrupi Acaciae ffjss. Misce. Signa. — A teaspoonful every two or three hours. ASTRINGENTS. 217 In the exhaustive stage of cholera infantum. Great care should be taken to have the syrup perfectly pure and clear ; a syrup made extemporaneously, or a thick mucilage, not being adapted to preserve the salt from rapid change. [620. Mixture of Sulphate of Soda and Opium.'] R. Sodas Sulphatis gr. xviij ; Tincturas Opii gtt. vj ; Aquas Cinnamomi f^ss; Syrupi Acacias f^j. Misce. Signa. — Give a teaspoonful every two hours. In the diarrhoea or summer complaint of children ; this formula being adapted for a child about one to one and a half year old. L. D. Harlow. [621. Mixture of Chloroform and Sulphate of Soda.~\ R. Chloroformi «ix; Alcoholis deodorati f ^ss ; Sodas Sulphatis 3ss ; Aquas Menthas Piperitas f^ijss. Misce. Signa. — Take a tablespoonful every hour until relieved. An effectual remedy in the diarrhoea of hot weather or from relaxation of the bowels. If much pain be present, a few drops of laudanum, or if acidity, five grains of bicar- bonate of soda may be added to each dose. 622. Solution of the Perchloride of Iron. R. Ferri Chloridi 3ij ; Aquas f^j. Solve. Signa. — Apply with a brush. Used to arrest gangrene or hemorrhage resulting from dis- ease, or accident, or in consequence of surgical operations. If the solid perchloride of iron be kept in a bottle, a small portion of it, after a time, deliquesces into a thick brown liquid, which is constantly kept in a state of supersaturation, by the undeliquesced portions of the salt. This liquid, applied by means of a spun-glass brush to a bleeding surface, arrests the flow of blood almost immediately. J. Zachariah Laurence. 218 ASTRINGENTS. 623. MonseVs Solution. 3k R. Liquoris Ferri Subsulphatis f^iv. Signa. — Apply as an astringent lotion. Like the solution of the perchloride of iron, this is a power- ful styptic and antiseptic. It has been extensively employed for arresting hospital gangrene, and for checking hemorrhages and abnormal discharges. 624. Alum Whey. R. Lactis Vaccinas bullientis Oj ; Pulveris Aluminis 3ij. Coque per sextam horse partem, et cola. Signa. — A cupful to be taken occasionally. In diabetes and passive hemorrhages. Foy. 625. Mixture of Gallic Acid and Morphia. R. Acidi Grallici 3j ; Morphias Acetatis gr. j ; Alcoholis f 3j ; Syrupi Tolutani f3iij ; Aquas f^iijss. Misce. Signa. — Dose, a tablespoonful. Used in the London City Hospital for checking night- sweats in consumption. Hutchinson. 626. Aromatic Syrup of Galls. E. Pulveris Gallse §ss ; Pulveris Cinnamomi, Macis, aa 3ij ; Spiritiis Yini Grallici fiviij. Misce, et macera per horas viginti quatuor. Having been allowed to stand twenty-four hours, the re- sulting tincture is filtered into a saucer. Then two ounces of sugar, in lumps, are suspended on wire gauze just above the surface of the liquid. The latter is set on fire, and the flame melts the sugar and converts it partly into caramel, which drops into the liquid beneath. When the combustion stops, the syrup is stirred and filtered for use. The dose is a table- spoonful for an adult. It is used in diarrhoea and chronic dysentery. Jos. Paeeish. ASTRINGENTS. 219 [627. Mixture of Hydrochloric Acid and Galls.] R. Acidi Hydrochlorici diluti fflxxxvj ; Syrupi Gallas Aromatici (Formula 626) f^ss ; Syrupi Acacias f£j. Misce. Signa. — Give a teaspoonful every two or three hours. In the diarrhoea of young children, following cholera in- fantum. If a great deal of debility is present, Huxham's tincture or one of the elixirs of bark may be substituted for the syrup of gum. 628. Mixture of Extract of Bhatany, &c. R. Extracti Krameriae 3j; Syrupi Papaveris (Lond.), Aquas Kosae, aa f^ij. Fiat mistura. Signa. — A teaspoonful for a dose. Given in passive hemorrhage and chronic dysentery. M. FOUQUIER. 629. Solution of Acetate of Lead. R. Plumbi Acetatis gr. v; Aceti gtt. v ; Sacchari 3j ; Aquas f^j. Fiat mistura. Signa. — Give a teaspoonful to a child every hour or two, to allay the vomiting in cholera infantum. D. F. Condie. 630. Enema of Acetate of Lead, etc. R. Plumbi Acetatis 9j ; Tincturae Opii gtt. lx ; Aquae tepidae f ^ij. Fiat mistura. Signa. — To be thrown up the rectum in uterine hemorrhage. W. Dewees. 631. Tannin Suppository. R. Acidi Tannici 3j; Olei Theobromae ^ss. Misce cum leni calore, et riant suppositoria iv. Employed in cases of bleeding piles, fissures of the anus, and mucous discharges from the rectum. Trousseau. CLASS XVII ABSORBENTS, OB ANTACIDS. Absokbents or Antacids form a class of remedies for cor- recting acidity in the stomach and bowels. As a general rule they should be preceded by an emetic or cathartic, or both. When a permanent effect is desired, they are usually com- bined with tonics and aromatics, and sometimes with narcotics. When given alone, they too frequently afford but transient relief. Powders and Pills. 632. Compound Cretaceous Powder with Opium. R. Cretae Praeparatae 3jss; Pulveris Cinnamomi jj ; Pulveris Piperis Longi gr. viij ; Pulveris Opii gr. vj. Divide in chartulas xij. jSigna. — One three or four times a day. In diarrhoea. The above formula, with a slight alteration, is from the London Pharmacopoeia. 633. Powder of CraVs Claws and Rhubarb. R. Chelae Cancrorum 3j ; Pulveris Ehei 9ij. Misce, et divide in pulveres iv. Signa. — One may be taken once or twice a day, according to circumstances. In acidity of the primae viae. This preparation is called by the several names of crab's claws, eyes, and stones. It is a carbonate of lime united with some animal gelatine. ABSORBENTS, OR ANTACIDS. 221 634. Powder of Magnesia, Fennel-seed, and Cinnamon. R. Magnesias Iss ; Pulveris Foenicnli, Pulveris Cinnamomi, aa 5j- Fiat pal vis. Signa. — Dose, a small teaspoonful three or four times a day. Given in dyspepsia, attended with acid eructations. 635. Powder of Magnesia, Soda, and Ginger. R. Magnesias Iss; Sodas Bicarbonatis, Pulveris Zingiberis, aa 9j. Misce. Signa. — A small teaspoonful occasionally. - In cardialgia. 636. Powder of Magnesia and Columbo. R. Magnesias 3jss. Pulveris Calumbas 3j. Misce, et divide in chartulas vj. Signa. — One may be taken three times a day, in sugar and water. In cardialgia. 637. Povjder of Charcoal, Carbonate of Magnesia, and Ginger. R. Carbonis Ligni 5j ; Magnesias Carbonatis 3'\j ; Pulveris Zingiberis 9j. Misce, et divide in pulveres iv. Signa. — One powder to be taken three times daily. Used in dyspepsia, accompanied with acidity. E. DUNGLISON. 638. Pills of Soda, Rhubarb, etc. R. Pulveris Ehei, Sodas Carbonatis exsiccatas, Extracti Gentianas, aa 9j ; Hydrargyri Chloridi Mitis gr. iij. Fiant pilulas xx. Signa. — One pill an hour after each meal. Given in dyspepsia, attended with constipation. 222 Mixtures, Solutions, etc. 639. Compound Chalk Mixture. R. Misturae Cretae f£v; Tincturse Catechu, Tincturae Opii Camphoratse, aa f 3ss. Misce. Signa. — A tablespoonful every three hours. Prescribed in diarrhoea, accompanied by acidity or flatu- lence. 640. Mixture of Salt of Tartar. R. Potassae Carbonatis Purae 3j ; Sacchari 3ij ; Aquas Mentha? Piperita? fjiv;. Spiritus Lavandulae Compositi f 3ij ; Tincturae Opii n^xl. Misce. Signa. — A tablespoonful every two hours. In sickness of the stomach, attended with acidity. 641. Mixture of Salt of Tartar and Ammonia. R. Spiritus Ammoniae Aromatici f 3j ; Potassae Carbonatis Purae 3ij ; Syrupi Zingiberis f 3yj ; , Aquas f^iv. Misce. Signa. — A large teaspoonful for a dose. In pyrosis and acid eructations. 642. Mixture of Lime-water and Milk. R. Liquoris Calcis, Lactis recentis, aa f^iij. Misce. Signa. — One or two tablespoonfuls for a dose. In sickness of the stomach few remedies are more, prompt in their effect. [643. Syrup of Lime.] R. Calcis Hydratae 3j ; Sacchari Pulveris ^ij ; Aquae destillatae Oj. Misce, et digere per horas duas et cola. ABSOEBENTS, OE ANTACIDS. 223 This preparation contains over seven grains of lime in each fluidounce, and may be given in doses of two or three flui- drachms to adults, or half a drachm to a young child, as an antacid in nausea. P. Squiee. 644. Magnesia-water. R. Magnesias £ij ; Aquas bullientis f^iv. Misce. Signa. — Give a dessert-spoonful of the clear fluid every two hours. This is an excellent antacid remedy, adapted to children. It is highly aperient. B. Ellis. 645. Mixture with Ammonia, Magnesia, etc. R. Magnesias 3j; Spiritus Ammonias Aromatici f 3j ; Spiritiis Cinnamomi f 5iij ; Aquas f 3vj. Misce. Signa. — A tablespoonful every two hours. In the sickness accompanying pregnancy. 646. Decoction of Columbo, Salt of Tartar, etc. R. Calumbas 3ss; Aquas f^viij. Coque ad f^v, cola, et adde — Potassas Carbonatis Puras gr. x ; Succi Limonis f 3iij ; Tincturas Opii gtt. xij. Misce. Signa. — From a teaspoonful to a tablespoonful may be given every hour. Anti-emetic. 647. Tonic Mixture with Carbonate of Soda. R. Sodas Carbonatis 9iv; Infusi Gentianas Compositi, Aquas Cinnamomi, aa f^iij ; Tincturas Cardamomi fgss. Fiat mistura. Signa. — A tablespoonful every two or three hours. In acidity, flatulence of the stomach, etc. 224 [648. Soda Mint] R. Sodas Bicarbonatis 3ij ; Spiritus Ammonias Aromatici gtt. xl ; Aquas Menthae Piperitae f Jviij. Misce. Signa. — Dose, a teaspoonful for an infant. An effectual carminative antacid in the colic of new-born children ; useful also in larger doses in acidity and flatulence of adults. 649. Dyspeptic Lye. Take of Hickory ashes 1 quart. Soot 6 ounces. Boiling water 1 gallon. Mix, and let them stand for twenty-four hours, frequently stirring the ingredients. A teacupful may be given of this liquor (decanted) three times a day. It should be decanted always at the end of twenty-four hours, for, by standing on the materials a long time, the water acquires caustic properties, and may do serious injury. This domestic remedy we have thought best to give, as we received it, in the English language. It deserves an inser- tion, from the circumstance that it was employed by the late Dr. P. S. Physick, in his own case, and was of decided advan- tage when the usual alkaline remedies had failed. B. Ellis. BOOK II OF EXTERNAL APPLICATIONS CLASS XYIII CAUSTICS, OB ESCHAEOTIOS. Caustics or cauteries are divided into the actual and poten- tial. The first consists of fire itself; and the second, of those substances which destroy the living solids, either by excessive stimulation, or, as some suppose, by producing a chemical decomposition. 650. Actual Cautery. The use of iron heated to a white heat as a cautery extends back.to the most ancient times. It is still occasionally em- ployed in the treatment of diseases of the spine and joints; and also to arrest hemorrhage by searing incised or wounded surfaces. But the particular modes of its application belong more properly to the regular treatises on surgery than to a work of this kind. 651. Firing. A modified form of the actual cautery has attracted some attention in Europe, from its great efficacy in the relief of neuralgic and other pains, paralysis, sciatica, and chronic rheumatism. Dr. Corrigan, of Dublin, uses a simple instrument, consist- ing of a thick iron-wire shank, two inches long, inserted in a small wooden handle, and having on its extremity, which is slightly curved, a button of iron a quarter of an inch thick and half an inch in diameter, the whole instrument being only six inches long. The face of the button for application is quite flat. If the instrument be larger than this, it will require too much time to heat it ; if smaller, it will not retain the heat a sufficient length of time. In using the instrument, it is necessary to hold the button over the flame of a spirit- lamp, keeping the forefinger, which holds the wire, at the 228 CAUSTICS, OR ESCHAROTICS. distance of half an inch from the button. As soon as the finger feels uncomfortably hot, the instrument is ready for use. It is applied as quickly as possible, the skin being tipped suc- cessively, at intervals of half an inch, over the whole affected part, as lightly and rapidly as possible, always taking care to bring the flat surface of the button fairly in contact with the skin. In this way the process of firing a whole limb or the loins, making about one hundred applications, does not occupy a minute. You can ascertain at once whether the heat be sufficient. If you look sideways at the spots as you touch them, you will observe that each spot the iron has touched immediately becomes of a glistening white. The iron is never red-hot, and does not make an eschar. — Braithwaite's Retrospect, No. 13, p. 55. 652. Caustic Potassa. The Causticum commune acerrimum is the pure potassa. When mixed with lime, its activity is lessened, and it is then called Causticum commune mitius. Tor the best mode of applying this substance, see the remarks on Issues. As this caustic spreads rapidly and eats deeply, care should be taken not to leave it on too long, when in the neighborhood of large bloodvessels. When, however, we wish to arrest its effects, they may be neutralized at once by vinegar, or vinegar and water. 653. Vienna Paste (Potassa cum Calce). R. Potassse 5v; Calcis 3yj ; Alcoholis q. s. ut fiat magma. The paste is spread on the part to be cauterized, and is allowed to remain for ten or fifteen minutes, while the sur- rounding skin is protected by adhesive plaster. 654. Vienna Paste with Opium. B=. Potassae cum Calce 5ij ; Pulveris Opii 3ss ; Saponis Mollis q. s. Misce. This preparation is employed for the same purpose as the common caustic. OR ESCHAROTICS. 229 655. Vienna Paste with Morphia. B. Potassse cum Calce partes iij; Morphias Muriatis partem j ; Aquas q. s. ut fiat magma. Misce. The addition of the morphia modifies the painfullness of the caustic, without materially diminishing its activity. 656. Caustic of Filhos. R. Potassas partes ij ; Calcis partem j. Misce. The caustic is fused, and run into leaden tubes like nitrate of silver. It is a convenient form for the application of a powerful caustic to uterine growths or ulcers. 657. Lunar Caustic. This caustic is the nitrate of silver {Argenti nitras fusa) deprived of its water of crystallization, fused and cast into moulds. Its mode of application varies with the object in view. If designed as an antiphlogistic, or as a stimulant to old ulcers, it should be passed lightly and rapidly over the affected part. If used as a caustic, it should be pressed against the surface for a few seconds. The valuable and peculiar property of this caustic is the limitation of its action to the part to which it may be applied. 658. Burnt Alum. The Alumen Exsiccatum is made by depriving alum of its water of crystallization by heat. It is applied in powder to the fungous granulation of ulcers; and, mixed with an equal part of powdered sugar, is used to remove specks from the cornea. 659. Chloride of Zinc. This is a powerful escharotic, and is safe and certain in cases that require the destruction of a considerable thickness of the living tissues; "never causing violent pain in the affected parts, or any kind of irritative fever, or disorder of the digestive organs." " The epidermis having been removed by nitrate of silver, the chloride of zinc may be applied as a caustic by means of a moistened hair pencil, either alone or mixed with an equal 230 CAUSTICS, OR ESCHAROTICS. portion of oxide of zinc, or sulphate of lime, or according to the following form : — 660. Canquoinh Caustic Paste. R. Zinci Chloridi partes ij ; Farinas partes iij ; Antimonii Terchloridi partem j ; Aquse q. s. nt fiat pasta." This paste should be spread thickly on the diseased part. Dunglison's New Remedies, 6th ed. p. 694. 661. Caustic Paste of Chloride of Zinc. R. Zinci Chloridi, , Calcis Sulphatis, aa <|ss. Misce. This preparation is very liable to deliquescence, to prevent which a little flour may be added at the time of application. 662. Caustic Collodion. R. Hydrargyri Chloridi Corrosivi 3j ; Collodii Jj. Solve. When this solution is applied with a camel's hair brush to the surface of nsevi materni, warts, condylomata, etc., the ether evaporates and leaves a film of the caustic firmly at- tached to the nasvus ; ulceration occurs in a few days, a super- ficial slough separates and thus destroys the nsevus without disfigurement. Macke. 663. Sulphuric Acid. The mineral acids are all escharotic, though seldom em- ployed, on account of the difficulty of managing fluids when used in this way. Sulphuric Acid, mixed with saffron, is proposed by Yelpeau as one of the most effectual caustics. Mr. James Syme directs it to be mixed with an equal weight of sawdust to obtain a proper consistence to prevent spreading; the surrounding parts being protected by the application of a solution of gutta percha in chloroform. Mr. Syme has also employed a saturated mixture of sul- phuric acid and dried sulphate of zinc. An ordinary quill pen is charged with the mixture and drawn over the tumor in different directions, by which means the skin is soon corroded. OR ESCHAEOTICS. 231 The application is continued from day to day until the whole sloughs out. 664:. Acid Nitrate of Mercury. R. Liquoris Hydrargyri Nitratis Oj. This is a powerful caustic, and is much employed in Eng- land and on the Continent to destroy malignant ulcerations, particularly those of a cancerous character. It is applied by means of a camel-hair pencil, and the parts are then covered with lint. 665. Ointment of Arsenic. R. Acidi Arseniosi 3j; Adipis, Cerati Cetacei, aa 3yj. Signa. — Melt the cerate and lard over a slow fire, and then stir in the white oxide of arsenic, and triturate carefully in a glass mortar. Used to destroy cancerous tumors. Pharm. Chirurg-. In hot weather, arsenic may be advantageously rubbed up with basilicon ointment, to prevent its spreading on the sound parts. A scruple of the former, to half an ounce of the latter, makes a strong ointment. 666. Arsenical Paste for Dentists. R. Acidi Arseniosi gr. ij ; Morphias Sulphatis gr. j ; Creasoti q. s. Misce, flat massa. Used to destroy the sensibility of a carious tooth before plugging. Having cleansed the cavity, fill it with a portion of the paste, secured with a pledget of cotton or a bolus of wax. J. D. White. 667. Dubois's Arsenical Powder. R. Acidi Arseniosi 3ss; Hydrargyri Sulphur eti Eubri Ij ; Sanguinis Draconis 3ss. Fiat pulvis. Chiefly used in the French hospitals as a caustic to cancer- ous affections. Arsenic is sometimes applied in the form of a paste made with water, which is carefully laid over the part to be re- 232 CAUSTICS, OR ESCHAROTICS. moved, and renewed according to circumstances. 'When the slough forms, it should be dressed with a poultice, or with cerate spread on lint. It acts rapidly and requires watching, a remark that applies equally to all these pastes. 668. Caustic Glycerols of Iodine, R. Potassii Iodidi partem j ; Glycerinse partes ij, Solve et adde — Iodinii partem j. Fiat solutio. Employed in lupus, by painting the solution over the dis- eased part, and applying oiled silk or gutta percha paper to prevent evaporation. The application is attended by pain of variable intensity and duration. It has proved successful in obstinate cases, after other remedies had failed. Bichter. Lugol's " caustic solution of iodine"' corresponds in strength with the foregoing glycerole, water being substituted for the glycerin. It has long been a favorite remedy in lupus, and in tuberculous and hypertrophied conditions of the skin. 669. Solution of Sal Ammoniac. E. Ammonise Muriatis Ij; Aceti destillati f aij ; Aquae f 5iv. Fiat solutio. To be applied to venereal warts. Bell on Venereal. 670. Chromic Acid. This acid has lately been employed in Germany as an escha- rotic. It is said to be efficient, manageable, and less painful than the ordinary applications. A concentrated solution (3j-ij in water f^j) is applied by means of a glass rod. The solid chromic acid has to be used with care, on account of its penetrating action. 671. Moxa. This is another method of using the actual cautery ; and, as it is engaging the attention of physicians, we insert the usual mode of applying it. The Chinese employ this remedy by means of the mugwort. They separate this soft, lanuginous substance by beating, and form it into a cone ; the base of this is attached, by being wetted, to the skin, and the point set on fire. ISSUES AND SETONS. 233 Dr. Boyle recommends dipping cotton in a strong solution of nitrate of potassa, and inclosing pieces of it, thoroughly dried, in paper cylinders, about one inch in diameter, and an inch in height. Dr. Burne employs wood in a state of dry rot — touchwood. This only requires to be shaped properly, and it burns, he says, with certainty and steadiness, and is preferable to the other modes suggested ; some of which, as common cotton or lint, requiring the use of the bellows, and, when they have been dipped in nitre, demanding care to pre- vent the scintillations from injuring the surrounding parts. Gnn cotton, steeped in chlorate of potassa, and then tho- roughly dried and formed into cylinders, has also been recom- mended. The cylinders or cones of touchwood may be confined to the skin by a little adhesive plaster fixed to the edges. It has been proposed to place pieces of cold iron in the neighborhood of the part while the moxa is burning, in order to render the sensations more vague, and therefore less pain- ful. Moxa is used in diseases of the spine, paralysis, etc. etc. Sub-Class.— ISSUES AND SETONS. These remedies are employed as substitutes for blisters, especially when a permanent discharge is desired. There are three kinds of issues in common use, by either of which a discharge of purulent matter may be procured for any length of time that may be requisite. They are applied in different situations, according to circumstances, and some one of the following parts is generally chosen : the nape of the neck,*the hollow of the deltoid muscle, and between the shoulders or over the ribs in front. In the inferior extremi- ties they are most conveniently formed in the inside of the leg, either above or below the knee. 672. Blister Issue. To form this issue, it is merely necessary to apply a blister to any part in the usual manner ; the skin being thus re- moved, the discharge must be promoted by means of stimu- lating applications, as the cantharidal ointment, or the savin, or compound resin cerate. These may be alternated with mild liniments, in order to prevent the ulceration and conse- quent discharge from becoming excessive. 234 ISSUES AND SETONS. 673. The Pea Issue. There are two modes of forming this issue; the first is made by means of a lancet. The part is merely taken in the thumb and finger, and an incision made by passing the lancet through the skin. The wound should be kept open by means of orange peas, the common pea, a bean, or a piece of orris root. The second is formed with caustic potassa. The following extracts from the Surgeon 's Vade Mecum will exemplify the manner of forming the issue with caustic : — "The part is first to be covered with a piece of adhesive plaster, in the centre of which a circular hole has been cut of the size of the intended issue ; in this hole the caustic potassa, made into a paste with soap, is to be placed. The whole is then to be covered with another plaster, secured by a bandage, and suffered to remain for ten or twelve hours. Generally, in two or three days, an eschar begins to separate, when the opening should be filled with the substance made choice of." These substances are enumerated above. 674. The Seton. To form this artificial discharge, take the seton-needle, to which is attached a skein of silk, the latter being partially anointed with some oleaginous substance. The needle is to be passed completely through the part chosen for the opera- tion, after which it is removed, and the ends of the silk left hanging from the wound. It should be dressed every day, or twice a day, with some mild ointment; and if this be not suf- ficient to keep up the discharge, the more stimulating un- guents may be used, as mentioned when speaking of the blis- ter issue. CLASS XIX. EPISPASTIOS. " By the ancients, all the external applications which redden or inflame the skin were called Epispastics, and these were designated according to the several degrees of effect : the slightest, entitled phcenigmoi; the next, sinapismi ; the more active, vesicatorii; and the strongest, caustici" At the present day, the term is restricted to those articles which produce a serous discharge beneath the cuticle — the blister of common language. As a general rule, blisters should remain on the patient six or eight hours, in order to insure their full effect. There are individuals, however, whose skins are so delicate that a shorter application will answer every purpose; in children, it is seldom necessary to leave them on longer than three or four hours. When they are applied to the scalp, twelve hours are almost universally required; and Dr. Chapman directs the hair to be shaved, if possible, some hours before the applica- tion is made. The usual dressing, when the blister is taken of, is basilicon ointment, or simple cerate, according to the urgency of the case, or irritability of the system. In order to keep it open, the weak epispastic, or savin ointment, will be found sufficient. When the system is very prostrate, blisters should be ap- plied to the inside of the thighs, or over the spine ; for r when the circulation is languid in the extremities, they seldom draw well, and are even liable to produce gangrene by exhausting the little vitality that remains. In diseases attended with an asthenic condition, when there is essentially a depression of the vital powers, as in most cases of eruptive fevers, blisters should be used with very great caution, and, generally, avoided altogether. This is 236 EPISPASTICS. especially the case in the exanthemata of children, where the application of a blister often causes a deep slough, adding greatly to the previously existing prostration, and, in some cases, turning the balance against recovery. In such cases the rubefacients and superficial irritants are much to be pre- ferred. When, from peculiarity of constitution, strangury is pro- duced, we must take them off after three or four hours, and bathe the part with sweet oil, or apply a poultice, giving at the same time diluent drinks, such as flaxseed tea or barley water, with the sweet spirit of nitre, camphor, or parsley tea ; bladders, also, half filled with warm water, should be applied to the pubes. An opium suppository or injection will be found very advantageous. A poultice of ground flaxseed or starch is often serviceable, and a warm bath affords prompt relief. Prevention, however, is better than cure ; and in irri- table constitutions, or in persons disposed to strangury, the blistering ointment, before being spread, should be rubbed up with three or four grains of opium, and three or four times as much camphor. This preventive seldom fails. Blisters are rendered much less irritating by covering them with a fine gauze, which, if pressed in close contact with the plaster, will not prevent or materially retard its operation. It is seldom necessary to keep a blister on longer than to redden the skin, when a simple poultice will complete the vesication. In children this precaution is imperative. 675. Blistering Plaster. R. Cerati Cantharidis q. s. ut flat super alutam, emplastrum epispasticum, 6 x 6. 676. Blistering Ointment. II. Ceres Flavee, Kesinse, Adipis, aa Jvj. Liquefac cum leni calore, et adde graclatim — Pulveris Cantharidis 3vijss. Misce, et fiat unguentum. In employing this ointment, or the preceding cerate, the margin of the blister should be covered with adhesive plaster, in order to confine it to its place, and prevent its creating unnecessary irritation. Another mode is to draw straps across it diagonally, which plan we generally prefer ; it pre- vents the blister from rising in the middle, and thereby par- tially defeating its object. EPISPASTICS. 237 677. Instantaneous Vesication. The French practitioners have a process for raising an in- stant blister. A piece of linen or paper, being cut to the re- quisite size, is immersed in spirit of wine or brandy, Cologne water, oil of turpentine, or spirit of camphor, whichever is most readily obtained. It is then laid on the part to be blis- tered, taking care that the moisture does not wet the sur- rounding surface. The flame of a lighted taper is then applied quickly over the surface of the paper so as to cause ignition, which is almost instantaneous. At the conclusion of this operation, the cuticle is found detached and raised from the true skin beneath. 678. Cantharidin. This substance, more or less impure, has been used during the last few years as a substitute for the common blistering cerate. The pure cantharidin is too expensive for general use, but an impure article, sufficiently concentrated for ordi- nary purposes, can be readily obtained. The cantharidin blistering tissues and vesicating taffetas, now offered for sale, are of this character : — 679. Cantharidal Ether or Green Oil of Flies. R. Pulveris Cantharidis partem unam ; ^Etheris partes duas. Macera per dies tres et exprime. If this extract be applied undiluted twice, by means of a hair pencil, it produces, in children, free vesication in an hour or two ; and if applied three times in an adult, the same effect takes place in three or four hours. The ether evaporates, and the remaining green fixed oil operates like the canthari- des in substance. Oettinger. 680. Blistering or Cantharidal Collodion. R. iEtheris Cantharidalis (prepared as above), Collodii, partes asquales. Misce. It is computed that two scruples of this collodion are equal to four drachms of common blistering plaster. It is applied by a brush two or three times over the affected part. Oettinger. 238 EPISPASTICS. 681. Extract of Cantharides. During the winter of 1853, a simple aqueous extract of Spanish Flies, prepared by Professor Procter, was used ex- tensively in the Pennsylvania Hospital, and found to be a most efficient substitute for the blistering cerate. The appli- cation of it for six hours raised as free a blister as the cerate did in eight. Since the discovery, by the same gentleman, that cantha- ridin is soluble in oil, oleaginous extracts have been devised, thus proving the general correctness of Galen's plan of pre- paring an ointment by macerating the entire insect in melted lard for twenty four hours, and then straining by expression. An oleaginous extract, prepared by digesting the powdered flies in melted lard, is a most efficient substitute for the offi- cinal cerate. CLASS XX BUBEFAOIEITS. The substances called Rubefacients not unfrequently vesi- cate on very delicate skins. The term, therefore, is relative. They are employed for the same purposes as blisters, and are often good substitutes for them. 682. Mustard Plaster. R. Pulveris Sinapis Nigrse iij ; Aquas q. s. ut flat cataplasma. It is a very general practice to use vinegar in making this plaster, but if the mustard be pure, the chemical reactions, on which the irritant properties chiefly depend, are better devel- oped with water than vinegar. In fact, a high heat, or the use of a strong acid solution, materially checks the process. The uses of the mustard poultice are too well known to require description. It is frequently made by adding an equal quantity of wheat or rye flour; this should always be done for children, or other persons of delicate skins. It can- not generally be borne longer than half an hour or an hour. Great care should be taken to caution ignorant persons against too long-continued use of mustard in contact with the skin, as the slough produced by it is very deep and intracta- ble. Persons not unfrequently have gone to sleep under the soothing effect of a mustard plaster, to awaken in agony from this dangerous burn. If a mild rubefacient effect be desired, the mustard may be mixed with syrup or molasses, instead of water. When thus made, the plaster may be borne two or three hours. 683. Garlic Cataplasm. The garlic cataplasm is employed with the same intention as the mustard, though much less active. It may be made by 240 RUBEFACIENTS. bruising the cloves of garlic, and mixing them in a common poultice of bread and milk. 684. Onion Poultice. Onions are often used in cases of croup, and in diseases of the chest in children, as revulsives and antispasmodics. Having been partially roasted, mashed, and spread between the folds of thin muslin, they are applied over the chest, and are permitted to remain as long as they retain their warmth and moisture. Another onion poultice may be prepared by boiling thoroughly corn-meal until a soft mush is produced ; then cutting the raw onions very fine, and stirring the onion and juice into the hot mush; allowing to heat through, and then spreading upon cloths. Onion poultices make a most valua- ble application to the legs and arms of children threatened with convulsion. 685. Cataplasm of Mustard, Pepper, and Ginger. B. Sinapis Nigrae contusae Tbss; Pulveris Piperis, Pulveris Zingiberis, aa Ij ; Aquae bullientis q. s. ut fiat cataplasma. Signa. — To be applied to the region of the stomach in severe pain or sickness, or to the soles of the feet when revulsion is required. 686. Spice Plaster. R. Pulveris Caryophylli, Pulveris Piperis, Pulveris Capsici, Farinae, aa §j ; Aquae bullientis q. s. ut fiat cataplasma. Signa, — Let the plaster, thus prepared, be applied hot to the epigastric region. Employed for the relief of flatulence and sick stomach. 687. Clove Plaster. Quilt some powdered cloves in flannel, and wring them out in hot whiskey or alcohol. Thus prepared, they form an excellent external application in colic, and in irritability of the stomach, etc. BUBEFACIENTS. 241 688. Mercurial Ointment, Camphor, etc. R. ITnguenti Hydrargjri Ij; Olei Terebinthinae, Camphorse, aa 3ij ; Cerati Adipis §j. Misce, et fiat unguentum secundum artem. Used as a rubefacient over the hypochondriac region, when blisters are precluded. 689. Tartar-emetic Plaster. This may be made by sprinkling the powdered tartar emetic on the surface of a Burgundy pitch or adhesive plaster, or on one made by spreading basilicon, or simple ointment, on soft leather or linen. In either way the margin should be left clean. Tartar emetic requires a longer time to produce its effect than the ordinary blister; the irritation is of a peculiar and very painful kind, and its effects must be watched with ex- treme care. 690. Tartar-emetic Ointment. R. Antimonii et Potassas Tartratis 5jj Adipis ^j. Tere simul. This ointment, when applied to the skin, is a slow but cer- tain means of exciting an eruption. The officinal formula is two drachms to the ounce, a better strength for ordinary pur- poses. Dr. Kramer speaks highly of its use in acute inflammation of the tympanic membrane. It is to be rubbed over the mas- toid process. Hannay. 691. Lotion of Tartar-emetic and Corrosive Sublimate. R. Antimonii et Potassse Tartratis Jj; Hydrargyri Chloridi Corrosivi gr. v; Aquas f Sj. Solve, et adde — ■ Spiritus Lavandulae Compositi f3j. This solution is applied by rubbing it on the part. The rubomg should be continued for five or ten minutes, and after some hours a pustular eruption will appear. — Dr. Haunay's essay, Be Tartratis Antimonii usu extemo, p. 26. 16 242 RUBEFACIENTS. It has been nsecl in pertussis, dyspnoea, catarrh, etc., and in the removal of incipient tumors. It has been ascertained by the illustrious Jenner and others, that tartar emetic, employed for an undue length of time ex- ternally, will produce violent effects on the system. We find in a note in Beck's Medical Jurisprudence, vol. ii. p. 283, that Dr. Francis mentions two cases wherein tartar emetic ointment, excessively used, produced effects similar to those at times arising from the outward application of arsenic. Magendie and Brodie ascertained by experiments upon ani- mals, that, inserted into wounds, its effects resemble those pro- duced by its internal exhibition. 692. Granville's Antidynous Lotions. These preparations act with great celerity. They are formed of three ingredients, mixed in certain proportions, according to the urgency of the case, viz : — 1. Of a saturated solution of ammonia; 2. Of the spirit of rosemary; and 3. Of spirit of camphor. 1. The milder Ammonialed Lotion. R. Aquae Ammoniae Fortioris flj ; Spiritus Eosmarini (Phar. 1850) f5vj; Spiritus Camphor as f5ij. Misce. 2. The stronger Ammoniated Lotion. R. Aquae Ammoniae Fortioris f3x; Spiritus Eosmarini [Phar. 1850) f 5iv ; Spiritus Camphorse f3ij. Misce. The only point in which these formulas differ from the original by Dr. Granville is in the preparation of the spirit of rosemary. Our Pharmacopoeia directs the oil of rosemary to be dissolved in alcohol. Dr. Granville had it prepared "by taking two lbs. of the tips or small leaves of fresh rosemary, and eight pints of alcohol, which are infused together for twenty-four hours in a covered vessel, and after adding as much water as will first prevent the empyreumatic smell, distil over seven pints." As to the method of applying these counter-irritants, we shall use the words of their inventor, Dr. Granville. " First impregnate with the colorless and transparent liquid, either a piece of linen folded six or seven times to the size of the part intended to be covered, or a piece of thick and coarse flannel ; RUBEFACIENTS. 213 and, secondly, lay either of them on the spot, pressing with the hand at the same time, very steadily and firmly, the said linen or flannel, over which there should be placed a thick towel, doubled several times, so that not only the evaporation of the lotion may be impeded, but the hand employed in pressing the application to the part may not suffer damage from any evaporation, or from contact with the liquid. In some parts of the body more convenient than the others, the readiest and most effectual mode of pressing down the appli- cation is, by tying over it a towel or thick bandage ; bat to this mode there is the objection that we cannot, under certain circumstances, inspect the part as quickly and as often as re- quired, so as to judge, from the effect of the application, when to stop, or how long to persevere in using it." 1 When applied to the temples, forehead, jaws, or chin, great care must be taken to prevent the effluvia from affecting the eyes and nostrils. The skin should be examined in a minute or two after the application, in order to see the effect pro- duced. When the pain is severe after the lotion is removed, simple diluent washes, and warm water, which is perhaps the best, will speedily allay it. Vesication will generally take place in from two to five minutes, and even in a minute in some persons; but where cauterization is requisite, ten or twelve minutes may be necessary. The irritated or denuded surface may be dressed, according to existing indications, with a simple poultice, tepid fomentations, cerate, or irritating ointments. 693. Gonclrefs Pommade Ammoniacale. B. Adipis partes xxxij ; Olei Amygdalae Dulcis partes ij ; Aqu£e Ammonite Fortioris partes xvij. Melt the lard, mix the oil with it, and pour them into a wide-mouthed vial with a glass stopper ; then add the am- monia, close the bottle, mix the contents together by shaking, and keep the mixture in a cool place. If the skin is to be excited, perspiration to be re-established, or some subcuta- neous engorgement to be dissipated, the pommade is applied by friction with the fingers. But if a rubefacient effect is desirable, spread the ointment thickly on linen, and apply it for one or two minutes. For vesication, continue the appli- cation for five or six minutes ; and, by a farther continuance,, absolute cauterization is speedily produced. 1 Granville : Counter-Irritation, its Principles and Practice, p. 39. 244 RUBEFACIENTS. This, and the preceding ammoniacal preparations, are used in a great variety of diseases,, and in all cases when speedy and powerful counter-irritation is demanded ; as in neuralgia and rheumatic affections generally, both acute and chronic ; spasms, convulsions, gout, paralysis, inflammatory diseases of internal organs, diseases of the heart, sprains, amaurosis, dis- eases of the eyes, etc. etc. 694. Caustic Solution of Potassa. R. Potassse 5jss ; Aquae fsij. Fiat solutio. Applied to the spine in tetanus. Dr. Joseph Hartshorne speaks in high terms of the benefi- cial effect of this solution in the above disease. The best mode of applying it, so as merely to produce a rubefacient action, is to tie a piece of sponge to a stick or common table fork, and apply it from the nape of the neck to the sacrum. "When the solution is strong, the effect is powerful. 695. Concentrated Tincture of Cayenne Pepper. R. Pulveris Capsici 3iv ; Alcoholis f oxij. Macera per dies septem et cola. This powerful rubefacient is recommended .as an embroca- tion for toothache and neuralgic affections. A. Turxbull. 696. Turpentine Liniment. R. Olei Terebinthina3, Olei Olivse, aa ,lij ; Spiritus Camphorae f Jj ; Aquas Ammonias f5j. Fiat linimentum. This is a good combination, and it may be used in most cases in which a prompt rubefacient is indicated. It is an effective agent for the relief of tympanitis, whether occurring after dysentery or diarrhoea, or arising in the progress of low fevers. For this purpose it should be well rubbed over the abdomen several times daily. 697. Liniment of Cantharides. R. Pulveris Cantharidis ,?j ; Olei Terebinthinae flviij. Digere per horas tres in vase leviter clauso, et cola. RUBEFACIENTS. 245 This liniment was first made by Dr. Jos. Hartshorne, of this city, who nsed it with great success in typhoid fever. It is merely rubbed over the surface of the body. S. G-. Morton. 698. Compound Liniment of Cantharides. R. Cainphoras 3iij- Solve in Linimenti Cantharidis f §ss ; et adde — Unguenti Hydrargyri, Unguenti Adipis, aa Ej. Fiat linimentum. This preparation is employed in low fever, when it is desir- able to rouse the system, and at the same time affect it with mercury ; also in tumors. S. Gr. Morton. 699. Liniment of Croton Oil. R. Olei Tiglii, Olei Olivas, aa 3j- Fiat linimentum. Croton oil is one of our safest and most efficient rubefacients. Rubbed for a few minutes, or sometimes even for a few seconds, on the skin, it produces irritation and redness, followed in some hours by a pustular eruption. If the effect is too severe at first, it is readily counteracted by a poultice, preceded by washing with mild soap and water to remove the oil. In some persons the oil may be applied pure. [700. Liniment of Croton and, Oil of Amberl\ R. Olei Tiglii gtt. xx ad xl. Olei Succini rectiflcati f ^j. Misce, et fiat linimentum. A most efficient liniment for the throat or chest in croup, catarrh, or pneumonia. Ellwood Wilson. 701. Volatile Liniment R. Olei Olivas, Aquas Ammonias, aa f^j. Misce. Applied to the neck in inflammation of the throat. It is also used for sprains and bruises, and for enlarged glands. 246 KUBEFACIENTS. 702. Ammordaied Soap Liniment. R. Linimenti Saponis f^ij; Aquas Ammonias f 3j ; Tincturas Opii f^ss. Fiat linimentum. This may be beneficially employed in the same class of diseases as the volatile liniment. Iodine. Iodine is used in different forms as a rubefacient and counter- irritant. It produces local alterative effects when applied externally, and hence is much employed for the discussion of buboes, goitre, enlarged glands, and diseases of the joints. The officinal tincture is generally recommended, and is applied to the diseased part by a camel's hair pencil. The following formulas furnish solutions of different strengths, which prove satisfactory in practice. 703. LugoVs Rubefacient Solution. R. Iodinii 5ss; Potassii Iodidi 5j ; Aquas f3yj. Misce. Used for touching the free margins of the eyelids and nos- trils in scrofulous ophthalmia, and strumous affections of the mucous membrane. Lugol. 704. Iodine Paint. R. Iodinii gr. lxiv; Potassii Iodidi gr. xxx ; Alcoholis f 3J. Fiat solutio. King's College Hospital. 705. Ethereal Solution of Iodine. R. ^Etherisflj; Potassii Iodidi gr. xv ; Iodinii q. s. ad saturandum. Misce. "It is applied in the same way as the tincture, by means of a camel's hair pencil rubbed over the part, until it begins to produce a burning sensation ; then cover it with a pledget of wadding, so as to prevent evaporation." E. Thomson. RUBEFACIENTS. 247 706. Liniment of Groton Oil and Potassa. R. Olei Tiglii, Liquoris Potassaa, aa nix v. Misce, et adde — Aquas Kosas fjj. Fiat linimentum. This may be rubbed on the affected part twice or three times a day, until minute pustules appear. James Allen. 707. Goiuhage Ointment. R. Mucunae gr. viij ; Adipis Bj. Fiat unguentum. The ointment must be rubbed in from ten to twenty minutes. The immediate effect is a sensation resembling stinging with nettles, but this passes off in less than half an hour. The skin generally becomes covered with white papules, which soon disappear. It is used in the same cases as the tartar emetic, or the Croton oil liniment. Blatin. CLASS XXI ANOMALOUS EXTEESAL APPLICATIONS. It was the original intention of the author of this work to arrange all the prescriptions, whether for internal or external use, under their appropriate therapeutic heads, and a few of the earlier editions conformed, more or less, to this view. But the introduction of a great number of new remedies, the true value of which can only be determined by careful trials, has caused much difficulty in arranging them properly in that respect. This remark is particularly applicable to the host of articles used, under various forms, in the skin diseases. To remedy this, and to facilitate reference as much as possible, the Editor has added the present class, which is arranged on a pharmaceutical, rather than a therapeutical basis, and its subdivisions are named according to the form of preparation employed, viz : Collyria, Injections, Gargles, Liniments, Oint- ments, Cataplasms, Baths, Fomentations, and Fumigations. A. — COLLYEIA. These are preparations applied to the eyes. They are sometimes dry, but generally liquid — consisting of infusions, decoctions, or distilled waters, with the addition of various medicinal substances. Powders. 708. Dry Gollyrium of Oxide of Zinc and Sugar, R. Sacchari, Zinci Oxidi, aa partes sequales. Tere in pulverem. COLLYEIA. 249 The ends of a quill having been cut off, a small quantity of the powder is placed in the barrel, and is gently blown into the eye. M. Kecamier. 709. Dry Collyrium of Red Precipitate and Oxide of Zinc. B. Sacchari 3ij ; Hydrargyri Oxidi Kubri gr. x ; Zinci Oxidi 9j. Fiat pulvis subtilissimus. This, like the preceding powder, is used in opacities of the cornea, by blowing into the eye through a quill. DUPUYTREN". 710. Dry Collyrium of Opium and Calomel. B. Pulveris Opii gr. iv ; Hydrargyri Chloridi Mitis, Sacchari, aa 3j. Tere bene. This compound is blown into the eye for the removal of specks on the cornea resulting from inflammation. 711. Lapis Divinus. B. Aluminis, Potassae Nitratis, Cupri Sulphatis, aa ij ; Camphorse 3ss. The alum, nitre, and sulphate of copper are to be fused together, in a glazed earthen crucible, to drive off the water of crystallization, and the camphor is to be added near the end of the process. The cold mass is to be broken in pieces, and preserved in a closely stoppered bottle. This article is much employed on the Continent as an eye- wash, in the strength of two grains and upwards to a fluid- ounce of distilled water. Solutions and Mixtures. 712. Alum Collyrium. B. Pulveris Aluminis gr. viij ; Aquae Kosse f^j. Fiat solutio. To be applied to the eye in chronic inflammation, as well as in the purulent ophthalmia of infants. Moorfield's Hosp. Pharm. 250 COLLYEIA. 713. Collyrium of Iodine and Iodide of Potassium. R. Aquae Eosae flyj; Potassii Iodidi gr. xxiv; Iodinii gr. ij. Fiat collyrium. Signa. — To be applied to the eyes three or four times in the day. In scrofulous ophthalmia and ulcerations of the cornea and conjunctiva. It is also serviceable in removing metallic specks from the cornea, by forming a soluble iodide with the metal. Eyan". 714. Collyrium of Green Vitriol. R. Ferri Sulphatis gr. ij ; Aquae f Jj. Fiat solutio. Used in chronic ophthalmia. 715. Collyrium of Subacetate of Lead and Wine of Opium. R. Liquoris Plumbi Subacetatis ^xij ; Vini Opii n^xl; Aquae Eosae f£iv. Fiat collyrium. This is an excellent eye-water, but it should not be used when there are ulcers on the cornea, as the lead might com- bine chemically with the base of the ulcer and form an in- delible mark. 716. Collyrium of Vinegar and Alcohol. R. Aceti destillati f 3j ; Alcoholis f^ss; Aquae Eosae fsviij. Fiat mistura. Signa. — To be applied to weak eyes. In chronic ophthalmias after depletion. 717. Collyrium of Acetate of Zinc. R. Zinci Acetatis gr. ij ; Aquae Eosae f^j. Fiat solutio. This is one of the best eye-waters in common use. It may be employed with great benefit in recent cases of COLLYRIA. 251 inflammation of the eyes. It should be dropped into the eye twice daily. 718. Alum Curd. R. Pulveris Aluminis 5ss; Albumen unius ovi. Fiat coagulum. Signa. — To be applied on a linen rag to inflamed eyes. It should be removed in three or four hours. 719. Collyrium of Nitrate of Silver. R. Argenti Nitratis gr. j ; Aquae destillatae fgj. Fiat solutio. Signa. — Used by dropping into the eye. In acute ophthalmia, and to promote the absorption of specks upon the cornea. 720. Collyrium of Sulphate of Cadmium. R. Cadmii Sulphatis gr. iij ; Aquae Kosas f 5ij ; Yini Opii f 5j- Fiat mistura. Used for opacities of the cornea, and in chronic ophthalmia. The quantity of sulphate of cadmium is gradually increased to four grains in an ounce. Fronmuller. 721. Camphorated Collyrium of Sulphate of Copper. R. Cupri Sulphatis gr. vj ; Aquas Camphorae f^viij. Solve. Signa. — To be dropped into the eye. This is nearly the same as the formula recommended by Mr. Ware in the treatment of purulent ophthalmia. [722. Collyrium of Borax and Opium.~\ R. Sodae Biboratis gr. xx; Yini Opii gtt. x; Aquae Eosae f^j. Misce. In cases of chronic conjunctival congestion. T. G. Morton. 252 COLLYEIA. 723. Collyrium of Prussic Acid. B. Acidi Hydrocyanici diluti f3j ; Aquas destillatas f3vij. Misce. A few drops are placed in the eye in irritable ophthalmia, as also to remove the conjunctival stains made by nitrate of silver. Mooefield's Hospital Pharm. 724. Collyrium of Gallic Acid and Opium. B. Acidi Grallici gr. x; Glycerinas 3ij ; Extracti Opii gr. x ; Aquas f^ij. Misce et cola. Signa. — Apply a few drops to the eye night and morning. This is a mild astringent lotion, useful in cases of chronic ophthalmia. 725. Strychnia Collyrium. B. Strychnias gr. ij ; Acidi Acetici diluti, Aquas destillatas, aa f^j. Fiat solutio. Signa. — A drop or two, diluted or not according to circum- stances, to be applied to the eye several times a day. Dr. Eyan on Amaurosis. [726. Collyrium of Atropia and Tanning B. Atropias Sulphatis gr. j ; Acidi Tannici gr. v-xx ; Grlycerinae puras f 3j ; Aquas Eosas f^j. Misce. In chronic, irritable, granular conjunctivitis. T. Gr. Morton. 727. Collyrium of Corrosive Sublimate. B. Hydrargyri Chloridi Corrosivi gr. ij ; Ammonias Hydrochloratis gr. vj ; Aquas destillatas f^viij. Fiat solutio. The above may be advantageously used in gonorrhoea! or scrofulous ophthalmia, as also to remove opacity of the cor- COLLYBIA. 253 nea, after the subsidence of inflammation. Known as Mac- kenzie's wash. 728. Colly rium of Opium and Camphor. R. Extracti Opii gr. x; Camphorae gr. vj ; Aquas ferventis f^xij. Tere simul et cola. The anodyne nature of this preparation is supposed to afford some advantage over ordinary lotions, in painful affections of the eye. [729. Decoction of Quince Seed.] R. Cydonii Seminum 3ij ; Aquae destillatae Oj. Coque lente, per sextam partem horae et cola. A mild soothing application in acute ophthalmia. London Pharmacopoeia. 730. Conradi's Collyrium. R. Hydrargyri Chloridi Corrosivi gr. j ; Decocti Cydonii (Formula 729)"f3j ; Aquae Kosas f^vj ; Yini Opii f3j. Fiat mistura. This collyrium is praised by most of the German oculists in cases of chronic ophthalmia. 731. Bates's Camphorated Water. R. Cupri Sulphatis, Boli Armeniae, aa gr. viij ; Camphorae gr. ij ; Aquae bullientis f I viij. Fiat infusum et cola. This is used as a lotion in the purulent ophthalmia oi infants. 732. Collyrium of Spirit of Minder er us and Camphor Water. R. Liquoris Ammonias Acetatis f oij ; Aquae Camphorae flyj. Misce. Signa. — For eyes requiring a mild astringent and stimulant application. 254 COLLYRIA. 733. Colly Hum of Spirit of Minder er us with Opium. R. Extracti Opii gr. x; Aquae ferventis f^vj. Solve, cola, et adde — Liquoris Ammoniae Acetatis f 3ij. Used in acute ophthalmia, when considerable pain remains after depletion. [734. Oollyrium of Corrosive Sublimate, Opium, etc."] R. Hydrargyri ChlOridi Corrosivi gr. J; Extracti Opii Aquosi gr. viij ; Decocti Cydonii f5ss; Aquae Rosae f^iv. Misce. Eor application after the removal of the foreign bodies, or in superficial burns. T. Gr. Morton. 735. Emollient Oollyrium. R. Altheae contusae 3ij ; Aquae destillatse Oj. Macera per horas tres, et cola. In inflammation of the conjunctiva accompanied with vio- lent irritation. 736. Colly rium of Poppies and Camphor. R. Decocti Papaveris, Lond. f aiv ; Aquae Rosae, Aquae Camphorae, aa fsij. Misce. This is adapted to the early stages of ophthalmia. 737. Oollyrium of Wine of Opium. R. Yini Opii, Aquae destillatae, aa f 3ss. Misce. This is found beneficial in rheumatic ophthalmia, when all the febrile symptoms are gone, and little more than lingering redness with weakness of the eye remains, by being dropped into the eye twice daily. Mackenzie. INJECTIONS. 255 738. Colly rium of Conia. R. Comae partes ij ; Alcoholis partes xiij ; Aquae destillatae partes cc. Fiat sokitio. Employed in scrofulous ophthalmia, with intolerance of light, by rubbing it around the orbits, or dropping it in the eye several times a day. Conia, the active principle of conium maculatum, is a viru- lent poison, and therefore care is requisite, even in its exter- nal use. Fronmuller. 739. Guthrie 1 s Ointment. R. Argenti Nitratis gr. ij ; Liquoris Plumbi Subacetatis n^xv ; Unguenti Cetacei, Lond., 3j- Fiat unguentum. " The manner of using the ointment, is by introducing be- tween the lids a portion, larger or smaller, as the case may seem to require, from the size of a large pin's head to that of a garden pea." Guthkie. [740. Colly rium of Nitrate of Silver and Atropia.] R. Argenti JSTitratis gr. ij; Atropiae Nitratis gr. j ; Aquae destillatae f Jj. Misce. In atonic ulceration of the cornea. T. G. Morton. 741. Ointment of Bed Precipitate and Sutyhate of Zinc. R. Hydrargyri Oxidi Eubri gr. x; Zinci Sulphatis 9j ; Adipis 5ij. Fiat unguentum. Eecommended by Professor Dupuytren in obstinate chronic ophthalmia depending on a scrofulous diathesis. B. — INJECTIONS. Injections are liquid compositions of emollient, astringent, or stimulating substances. The parts into which they are 256 INJECTIONS. thrown are the external auditory passages, the nostrils, the canal of the urethra, the bladder, and the vagina; and also into fistulous cavities, and into the tunica vaginalis in the case of hydrocele. A. — FO R THE E AE. 742. Camphorated Injection of Cajeput Oil. R. Camphorae 3iv ; Olei Cajuputi f 3vij ; Olei Amygdalae Dulcis f 3xv. Tere simul. Sigrja. — A few drops to be dropped into the ear, in cases of dulness of hearing, from hardened wax, or dryness of the membrane. Eadius. 743. Goulard? s Extract and Rose Water. R. Liquoris Plumbi Subacetatis f 5j ; Aquae Bosae f^j. Misce. Signa. — This is to be dropped into the ear until the meatus is full, and be allowed to remain there for a few minutes. Used in otorrhoea. Wilde. 744. Mixture with Bates's Alum Water. R. Liquoris Aluminis Compositi, Lond n f 5j ; Aquas Bosae fsj. Misce. Used in otorrhoea, in the same way as the preceding. Wilde. 745. Mixture ivith Aqua Sappharina. R. Liquoris Cupri Ammonio-Sulphatis, Lond., f 3j ; Aquae destillatae f^j. Misce. Like the preceding, this is used as an astringent in otorrhoea. Wilde. 746. Solution of Nitrate of Silver. R. Argenti Nitratis gr. x; Aquae destillatae f |j. Fiat solutio. Used in simple otorrhoea by painting the meatus and mem- brana tympani with a fine camel's hair pencil, dipped in the INJECTIONS. 257 solution, every second or third day; and one of the three foregoing solutions is used in the interim, night and morning. Wilde. 747. Another Form. R. Argenti Nitratis 3ss; Aquae destillatae f 5J. Fiat solutio. This is recommended to be applied every third day to the outer half of the meatus, and adjacent portion of the concha, in chronic inflammation or thickening of the membrane lining the tympanic cavity. J. Toynbee. [748. Injection of Sulphite of Soda.] R. Sodas Sulphitis 9j ; Aquae destillatae fjj. Fiat solutio. For injection into the meatus in otorrhcea, connected with ulceration of the tympanum, and disease of the bones. 749. Injection of Pyroligneous Acid. R. Acidi Pyrolignei, Dub. f 3ij ; Aquas destillatae f Jvj. Fiat injectio. Signa. — To be injected twice a day with a silver syringe, in purulent discharge from the ear. Buchanan. 750. Injection of Catechu. R. Catechu gr. xij ; Aquae bullientis f ^vj. Infunde et cola. Signa. — To be used four or five times a day. Buchanan. 751. Pyroligneous Acid, Ether, and Turpentine. K. Acidi Pyrolignei, Dub., Spiritus iEtheris Sulphurici, Ed., Olei Terebinthinae, aa partes aequales. Misce. Signa. — Introduce two drops into the meatus auditorius exter- nus every night, when the cerumen is deficient in quantity. Buchanan. 17 258 INJECTIONS. 752. Injection of Creasote. R. Creasoti gtt. ij ; Alcoholis gtt. x ; Syrupi f 3j ; Aquae f3vij. Misce. To be used like the foregoing. 753. Solution of Sulphate of Cadmium. R. Cadmii Sulphatis gr. viij ; Aquae f^j. Fiat solutio. Used in otorrhoea, as an alterative and astringent to arrest the discharge. Lincke. B. — FOE THE NOSTEILS. Injection into the nostrils may be made by an ordinary glass or metallic syringe, pressed firmly into the anterior nares, the pipe of the syringe being directed backward, parallel with the roof of the mouth. The most efficient means, however, of bringing medicinal solutions in contact with the nasal membranes, is the use of the Thudichum douche, consisting of a bottle or other reservoir, having an aperture near its bottom, to which is attached a rubber tube, having at its extremity a plug capable of completely stopping the external nostril. In using it the medicated fluid is put into the bottle, the plug of the tube inserted tightly into the nostril, the mouth opened wide, and forcible respiration made through it ; when the bottle is raised above the level of the head, the liquid passes by gravitation into one nostril, filling the maxillary sinuses upon that side, and, not being able to pass into the pharynx from the closure of the posterior nares, is carried around the septum into the meatus of the other side, and passes from the other nostril, thus washing out the whole nasal apparatus, with its connecting sinuses, maxillary and frontal, without running down the throat. It is necessary to use great care in keeping the mouth open wide, and breath- ing forcibly, otherwise the fluid will run down the throat, and cause suffocation. The ordinary injection used by Dr. Thudichum in ozsena or nasal catarrh, consists of a tablespoonful or two of common INJECTIONS. 259 table salt in a pint of tepid water. Other formulas are as follows, all of which I have used with good results: — [754. Douche of Permanganate of Potassa.] R. Potassas Permanganatis gr. xvj ; Aquas puras Oj. Misce. Signa. — Use, three or four times daily, about two or three tablespoonfuls at a time. [755. Douche of Iodide of Zinc and Permanganate of Potassa.] R. Potassas Permanganatis gr. xvj ; Zinci Iodidi 3ss; Tincturas Myrrhas fsij ; Aquae Oj. Signa. — Use three or four times daily. In ozasna, offensive nasal discharge, and frontal pain from disease of the sinus. [756. Douche of Hyposulphite of Soda.'] R. Sodas Hyposulphitis 3iij ; Aquas Oj. Misce. Signa. — As above, for the same conditions. [757. Douche of Alum.] R. Aluminis 9iv; Aquas Oss. Misce. For epistaxis. [758. Douche of Perchloride of Iron,] R. Ferri Perchloridi 9iv ; Aquas Oss. Misce. For epistaxis ; also catarrh. C. — FOR THE URETHRA. When injections are employed in the cure of gonorrhoea, two circumstances merit especial attention, viz., the manner of injecting them and the frequency of using them. "When the common syringe is used, the pipe should be perfectly smooth, 260 INJECTIONS. short, and conical, so that it cannot pass more than a quarter of an inch into the urethra. The patient should oil the pipe before using it, seat himself on the edge of a chair, so as to avoid pressing the perineum, draw the penis forward on the syringe with the left hand, and throw up the injection to the seat of disease (previously ascertained) with the other. As respects the frequency of injecting, it may be observed, that five or six times a day are not too often, and that the cure will be retarded by using these remedies at longer intervals. We cannot forbear remarking that gonorrhoeal inflammation, situated near the extremity of the penis, can be often cured by a routine plan; but when seated higher up the canal, and affecting Cowper's glands or the prostate, it becomes a serious disease, the cure of which ought not to be undertaken by persons ignorant of the structure of the parts and the nature of morbid action. 759. Nitrate of Silver. This article is extensively used, both in gonorrhoea and gleet. Some practitioners employ a weak solution, of two or three grains to the ounce of rosewater, twice a day. Others prefer ten grains to the ounce, aud employ the injection every second or third day. Another class prefer an ointment of ten or twenty grains to the ounce, and smear this over a bougie, which is then passed into the urethra. In acute gonorrhoea, either of the latter plans will frequently arrest the disease in a few days. In gleet, perhaps, the first plan is preferable. 760. Injection of Opium. E. Extracti Opii 9j ; Glycerinae f oj ; Aquae f^iij. Misce. Signa. — Use after every passage of urine. This affords great relief to the local pain and uneasiness, and causes a diminution of the discharge in gonorrhoea. F. J. Bumstead. 761. Injection of Corrosive Sublimate, etc. B. Zinci Sulphatis gr. x ; Hydrargyri Chloridi Corrosivi gr. ij ; Aquae Eosae f^viij. Fiat injectio. In sleet. INJECTIONS. 261 This powerful remedy should be employed with great cau- tion. 762. Injection of Sulphate of Zinc and Laudanum. B. Zinci Sulphatis gr. x ; Pulveris Acaciae 3ij ; Tincturae Opii f 3j ; Aquae destillatae f ^viij. Fiat injectio. In gonorrhoea virulenta. 763. Injection of Sulphate of Zinc and Acetate of Lead. B. Zinci Sulphatis, Plumbi Acetatis, aa gr. xx; Aquae Eosae f^iv. Misce. Signa. — Shake the bottle before using. Although mutual decomposition of the salts takes place, the resulting mixture forms an excellent injection for gonorrhoea. Eicokd. 764. Injection of Muriate of Ammonia, etc. B. Ammoniae Muriatis gr. j ; Hydrargyri Ohloridi Corrosivi gr. ij ; Aquae destillatae f^iv. Fiat injectio. In chronic gonorrhoea. 765. Injection of Acetate of Zinc. B. Zinci Acetatis gr. viij ; Aquae Rosae f siv. Fiat injectio. In gonorrhoea virulenta. For all these preparations, rosewater is an admirable men- struum ; it possesses the advantages of being slightly astrin- gent and rendered pure by distillation, and is therefore par- ticularly applicable to the formation of injections and collyria. 766. Injection of Chloride of Zinc. B. Zinci Chloridi gr. j ; Aquae f^j. Fiat solutio. 262 INJECTIONS. This injection has been used in St. Bartholomew's Hospital, London, with much success, by Mr. Lloyd, in cases of gonor- rhoea. Mr. Weeden Cooke recommends the simultaneous employment of the alkaline carbonates internally. 767. Injection of MonseVs Salt. R. Liquoris Ferri Subsulphatis fjss; Aquae f^vj. Solve. Signa. — Use for an injection. Eecommended in gleet. Bumstead. 768. Injection of Sulphate of Iron. R. Ferri Sulphatis gr. viij ; Aquae f §j. Fiat solutio. Used in gleet. 769. Injection of Iodide of Iron. R. Ferri Iodidi 3ss ; Aquae f 3 viij. Fiat solutio. Used in blennorrhoea. Kicokd. 770. Injection of Sulphate of Quinia. R. Quiniae Sulphatis gr. viij ; Aquae f §j ; Acidi Sulphurici diluti q. s. ut flat solutio. Used in gonorrhoea. Goddard. 771. Injection of Chlorate of Potassa. R. Potassae Chloratis 3ss ; Aquae f ^v. Fiat solutio. This has been used in a number of cases of gonorrhoea, speedily effecting a cure. A. S. Palmer. [772. Injection of Permanganate of Potash.] R. Potassae Permanganatis gr. j-ij ; Tincturae Myrrhae f 3ij ; Aquae f 3vj. Misce. In gonorrhoea. INJECTIONS. 263 773. Injection of Calomel, etc. B. Hydrargyri Chloridi Mitis 3j J Acaciae 3ij ; Tincturae Opii f oSS ; Aquas f ^viij. Fiat injectio. For gonorrhoea or gleet. 774. Injection of Sulphate of Copper. B. Cupri Sulphatis gr. vj ; Aquae destillatae f^vj ; Tincturae Opii f3j. Fiat solutio. To be thrown up the urethra in chronic gonorrhoea. 775. Injection of Yellow Root {Hydrastis Canadensis). B. Eadicis Hydrastidis contusae §j ; Aquae bullientis Oj. Macera per horas duas, et cola. Signa. — Inject an ounce three times daily. Dr. D. M. McCann, of Martinsburg, recommends highly this injection in gonorrhoea. Dr. U. E. Ewing also speaks favorably of it; but he directs a drachm of sulphate of copper to be dissolved in the infusion. 776. Injection of Tea. B. Folii These Yiridis 3j ; Aquae ferventis f^vj. Fiat infusum et cola. For an injection in gonorrhoea virulenta. 777. Iiijection of Copaiba. B. Copaibae 3v ; Yitellum unius ovi ; Extracti Opii gr. j. Tere simul, et adde gradatim — Aquae f^vij. Misce. Signa. — Inject a portion several times daily. This is an efficacious mode of treating gonorrhoea. Dallas. 264 VAGINAL INJECTION'S. 778. Injection of Ammoniated Copper. R. Cupri Ammoniati gr. v; Aquas Kosas f^viij. Fiat solutio. In chronic gonorrhoea. 779. Solution of Tannin. R. Acidi Tannici gr. xxxij ; Aquas destillatas f^viij. Solve. Employed as a wash to chronic ulcers, and as an injection in obstinate blennorrhoea. — Bebal, in Dung-lison's New Re- medies, 6th ed. p. 45. 780. Injection of Strychnia. R. Strychnias gr. j ; Acidi Nitrici "lij ; Aquas f^j. . Fiat solutio. Signa. — Inject a drachm three times a day after urination. Used in gleet. Johnson. C— VAGINAL INJECTIONS. 781. Injection of Permanganate of Potassa. R. Potassas Permanganatis gr. xx; Aquas Oj. Solve. Used in cancer of the womb for its alterant and deodorant effect, also in fetid lochial discharge in puerperal fever, a small quantity being injected several times daily. D. F. Giewood. 782. Injection of Greasote. R. Creasoti ^xij ; Mucilaginis Tragacanthas ^ij ; Aquas ferventis flxiv. Fiat mistura. Eecommended for the removal of the fetid and vitiated se- cretions from the maternal passages in puerperal fever. Warm INOCULATION AND INJECTIONS. 265 water is thrown up to wash out the vagina, and the injection is then used. It is employed in the same way for cancer of the womb. Mackenzie. 783. Injection of Labarraquds Solution. R. Liquoris Sodas Chlorinatas f %} ; Aquas f 3x. Misce. Prescribed as a vaginal wash in cases of infection produced by the decomposition of a retained placenta. Tkousseau. 784. Injection of Mustard. R. Pulveris Sinapis Albas 3ij ; Aquas ferventis Oj. Misce. Signa. — Inject a third part three times daily. Useful in amenorrhoea. S. Ashwell. 785. Vaginal Pessary of Tannic Acid. R. Ceras Albas 9v. Liquefac cum leni calore, et adde — Adipis 3yj ; Acidi Tannici 9ij. Tere bene et divide in pessos iv. Used in leucorrhosa and gonorrhoea of females. Simpson. 786. Vaginal Pessary of Alum and Catechu. R. Olei Theobromas 3ij ; Aluminis, Pulveris Catechu, aa 3j- Misce secundum artem et divide in pessos vj. Useful in chronic vaginitis and leucorrhcea. Inoculation and Subcutaneous Injection of Medicines. Inoculation. — The introduction of medicines into the skin by inoculation was proposed in 1836 by M. Lafargue, and has since been practised by M. Solon and M. Langenbeck. The latter has tried a number of experiments, whereby the value of this mode of medication has been fully proved. Inocula- tion is effected by making a number of punctures with a small 266 INOCULATION AND INJECTIONS. lancet through, the skin — including both the epidermis and the dermis — and rubbing the medicine, previously dissolved in the smallest possible quantity of fluid, into the punctured part. Some local irritation follows the operation. In this way, solutions of morphia, strychnia, quinia, iodine, corrosive sublimate, and of the various narcotic extracts, have been em- ployed with much success. The quantity of medicament used is about double of what would be administered by the mouth. Inoculation has proved effectual in sciatica, neuralgia, and local pains ; but it has not, however, attracted much attention from practical physicians. Subcutaneous Injection of medicines is more efficacious than inoculation, as in this way remedies can be more readily and certainly introduced. The operation is performed by means of a syringe capable of holding a nuidrachm, and having its perforated nozzle drawn to a point, by which the skin can be penetrated by a gentle rotary motion. Or a deli- cate trocar and canula may be used. The trocar having been withdrawn, the injection is made by a syringe through the canula. After the operation there are usually some swelling, tenderness, or pain, and a diffused redness of the skin. These local phenomena soon pass away, and the symptoms charac- teristic of the medicine are manifested on the system. No unpleasant local results need be anticipated, unless the quan- tity employed be large, or the remedy be of an acrimonious character. In all cases strong solutions are used, with a view of combining efficiency with smallness of bulk. A source of trouble in giving hypodermic injections exists in the occasional introduction of air through the syringe beneath the skin, the effect of which is generally to produce an abscess, very small usually, but still painful, and prevent- ing the introduction of the fluid at the same point, or even in its vicinity, for a considerable time after. To avoid this, great care must be used to get the instrument to work per- fectly air-tight, which can be tested by drawing up the fluid, and then discharging it under the surface without withdraw- ing it from the vessel in which the fluid is held ; if no air- bubbles are expelled from the nozzle, it is in proper working order. The following method of introduction has been found by the editor to answer better than the usual one, viz : having drawn the proper quantity of fluid into the syringe, with the nozzle applied, pinch up the skin, as far as possible, tightly between the thumb and forefinger of the left hand; then instantly plunge the needle of the instrument deep down into the eel- GAKGLES AND MOUTH WASHES. 267 hilar tissue, at an oblique angle, nearly to the hilt of the syringe ; then slowly expelling the fluid, press the finger upon the skin over the needle as it is withdrawn, to prevent any escape of the fluid. This has been found to be much less painful than when the needle is slowly and gently insinuated, and much less likely to be followed by swelling and redness than when the fluid is inserted very near the surface. Saturated solutions of tannin, and of the peracetate, perchlo- ride, and persulphate of iron, have been injected for the destruction of nasvi and small aneurisms. Dr. Alexander Wood, of Edinburgh, reported nine cases of neuralgia, in 1855, treated by injections of a strong solution of opium, over the seat of pain. In all relief was afforded, and in most a cure was effected. Dr. Horatio E. Storer injected, successfully, ten drops of a solution of the bimeconate of morphia (bimeconate gr. x, alcohol f 3j? and water f^xiij), beneath the mucous membrane of the gum for the relief of toothache in pregnant women. Dr. Scanzoni speaks favorably of the same preparation for neuralgia, and even for puerperal convulsions. Mr. Charles Hunter, of London, employed concentrated solutions of the acetate of morphia in cases of chorea, tic douloureux, delirium tremens, and hemicrania. The doses ranged from a half to three-fourths of a grain of the acetate. In every instance the peculiar effects of morphia were soon manifested. Drs. Courty and Cowdell report, severally, the injection of atropia, or its sulphate, in doses ranging from one-thirty-third to one-eighth of a grain in asthma, sciatica, and severe neural- gias. If the atropia be pure, these quantities are too large for ordinary use. Dr. Ignatius Danger, of Iowa, refers to twenty-three cases of intermittent fever cured by injections of sulphate of quinia. " He administered a solution of two to ten grains of sulphate of quinia in fifteen to thirty grains of water (with an addition of two to six drops of diluted sulphuric acid), according to age, constitution, duration of disease, and former treatment." D. — GARGLES AND MOUTH WASHES. Gargles, like injections, are astringent and stimulating, and to be of any service must be frequently applied, and perse- vered in for some time. 268 GAEGLES AND MOUTH WASHES. [787. Gargle of Sage and Flaxseed.} R. Salvias 3ij ; Seminis Lini ij ; Aquas bullientis Oj. Macera cum leni calore per duas horas; cola. An excellent gargle in the acute stage of pharyngitis or tonsillitis, when irritating and astringent applications are injurious. To be used cold. J. F. Meigs. 788. Gargle of Brandy. R. Spiritus Yini Grallici, Aquas, aa partes asquales. Brandy and water form an excellent gargle for some cases of inflamed fauces. 789. Gargle of White Oak Bark and Alum. R. Querciis Albas contuses 3j; Aquas Ojss. Coque ad Oj, cola, et adde — Aluminis 3ss ; Spiritus Yini Gallici f^ij. Misce. Used in sore throat and chronic ulceration of the fauces. 790. Gargle of Sulphate of Quinia, etc. R. Quinias Sulphatis gr. xij; Cupri Sulphatis gr. xvj ; Acidi Sulphurici Aromatici f 3j ; Aquas flviij. Fiat mistura. Signa. — To be used three or four times a day in obstinate sore throat. Jos. Haetshoene. 791. Gargle of Borax and Myrrh. R. Sodas Boratis 3j ; Tincturas Myrrhas fsss; Mellis despumati f sj ; Aquas Eosas f 3iv. Fiat gargarysma. To be used as a gargle or mouth wash, in ptyalism or scor- butic affections of the gums. GARGLES AND MOUTH WASHES. 269 [792. Mouth Wash of Borax and Honey. 1 R. Sodae Biboratis 3j ; Glycerinae f 3j ; Mellis despumati f 3yj. Misce. For application in aphthous ulceration of the mouth. P. Squire. 793. Gargle of Sulphate of Zinc, etc. R. Zinci Sulphatis 3j 5 Mellis f^ss; Tincturse Myrrhae f ,?j ; Spiritus Yini Gallici f oj ; Aquae Eosae f^vj. Fiat gargarysma. To be applied to ulcerated gums, occasioned by excessive salivation. Water can be added if it be too strong. 794. Dr. Blake's Toothache Solution. R. Aluminis (in pulverem subtilissimum triturandi) 3ij ; Spiritus iEtheris Nitrosi f3vij. Fiat mistura. Said by Dr. Blake, of London, to be an infallible cure for toothache, when not connected with rheumatism. 795. Gargle of Alum. R. Aluminis 3ij ; Aquae f^iv. Solve. This is Dr. Cavarra's gargle for fcetor oris, or offensive breath. 796. Gargle of Pomegranate and Alum. R. Granati Fructus Corticis 3ss; Eosae Gallicae 3ij ; Aquae bullientis fivj. Fiat infusum. Cola et adde — Mellis despumati f %j ; Aluminis 3ij- Fiat gargarysma. For inflammation of the throat and fauces. 270 GAEGLES AND MOUTH WASHES. [797. Gargle of Pomegranate, Chlorate of Potash, etc.'] R. Corticis Granati Fructiis 3ss; Potassas Chloratis 3ij ; Quercus Albas contusas 3j ; Aluminis ^ss ; Aquas bullientis Oij. Fiat infusum. Cola. In subacute and chronic pharyngitis. L. C. Heyl. 798. Gargle of Rhatany. R. Pulveris Krameriae, Pulveris Cinnamomi, aa £j ; Aquas bullientis f 3vij. Macera per horas duas, cola, et adde — ■ Sacchari §ij. Fiat gargarysma. A valuable astringent gargle in ordinary sore throat. 799. Muriatic Acid and Peruvian Bark Gargle. R. Infusi Cinchonas Eubras f^iv; Mellis despumati f 3j ; Acidi Muriatici nix. Fiat gargarysma. In chronic inflammation, when the pain and swelling have been rednced by depletion. Eatier's Formulary. 800. Detergent Gargle of Sulphuric Acid, etc, R. Decocti Hordei f liv ; Mellis despumati fiss ; Acidi Sulphurici n^x. Fiat gargarysma. Eatier. 801. Mercurial Gargle. R. Hydrargyri Chloridi Corrosivi gr. j ; Mellis despumati f 3ss; Aquas destillatas f^iv. Fiat solutio. For venereal sore throat. Batier. GARGLES AND MOUTH WASHES. 271 802. Sal Ammoniac and Acetic Acid Gargle. B. Acidi Acetici f 3ij ; Ammonia Muriatis 3j ; Mellis f 5Jss ; Aquae f^xij. Fiat gargarysma. For inflamed fauces. Eatiee. 803. Gargle of Acetate of Lead. B. Plumbi Acetatis 3ss ; Syrupi^j; Decocti Hordei Oj. Fiat solutio. In mercurial sore mouth, etc. Eatier. 804. Chloride of Lime Gargle. B. Calcis chlorinatae 3ij ; Aquae Oj. Solve et cola. Dein adde — Mellis ilj. Misce. Used in ulceration of the mouth and throat. 805. Disinfecting Mouth Wash. B. Calcis Chlorinatae 3iij ; Aquae destillatae f sij. Tere simul et ultra. Dein adde — Olei Eosae ntv ; Alcoholis f^ij ; Mellis Eosae fiss. Misce. Used in mercurial sore mouth. 806. Cayenne Pepper Gargle. B. Tincturae Capsici f^ss; Aquae Eosae fSviij. Misce. A stimulating gargle used in scarlet fever. Griffiths. 272 GAKGLES AND MOUTH WASHES. 807. Mel JEgyptiacum. R. Linimenti JEruginis (Lond.) f 5j. This is applied with a brush to venereal ulcers of the throat. Diluted with water (one drachm to the ounce), it forms a detergent gargle. 808. Gargle with Iodine and Opium. R. Tincturae Iodinii, Tincturae Opii, aa f 5j ; Aquae f^vj. Fiat gargarysma. Signa. — To be well shaken when used. This is employed three or four times daily in ulcerated sore throat. 809. Lotion of Iodide of Zinc. R. Zinci Iodidi gr. x; Aquae destillatae f^j. Fiat solutio. Applied daily to enlarged tonsils, by a piece of sponge tied to a quill. J. J. Eoss. 810. Mixture of Sulphuric Acid and Honey. R. Acidi Sulphurici f 3ss ; Mellis faj. Fiat linimentum. Used for aphthae, by touching the ulcerated surfaces fre- quently with a soft pencil. 811. Wash of Sulphate of Copper, etc. R. Cupri Sulphatis 5ij ; Pulveris Cinchonae Pallidas 3ss ; Aquae destillatae f.liv. Misce. Signa. — In the gangrenous sore mouth of children, applied to the full extent of the ulceration and excoriation. B. H. Coates. Sulphate of zinc is often employed in like doses in this affection. 273 812. Gargle of Alum, Sage Tea, and Honey. R. Salvias 3ss; Aquae bullientis Oss. Fiat infusum, et cola. Dein adde — Alumnus 3ss ; Mellis f 3j. Fiat mistura. This domestic remedy is very effectual in cases of sore throat. 813. Lotion of Muriatic Acid, etc. R. Acidi Muriatici f5ss; Mellis, Aquae Eosae, aa faj. Misce. Signa. — To be applied with a brush to scorbutic gums three or four times a day. E.— LINIMENTS, LOTIONS, ETC. 814. Lotion of Lime-water, Zinc, etc. R. Zinci Oxidi gr. xij ; Cupri Sulphatis gr. iij ; Mellis f 3j ; Liquor is Calcis f^ij. Fiat lotio. Signa. — To be applied to phagedenic ulcers of the genitals. Vide Swediaur on Syphilis. 815. Liniment of Lime-water and Linseed Oil {Carron Oil). R. Olei Lini f 3 iij ; Liquoris Calcis f^vj. Fiat linimentum. Signa. — To be applied to burns and scalds by means of a feather or soft rag. [816. Liniment of Carron Oil and Carbolic Acid.] R. Acid Carbolici liquidi f 3j ; 01. Lini, Liq. Calcis, aa fliij. Misce, et ft. linimentum. For application in the sloughing stage of deep burns and carbuncles, or any phagedenic ulcer. 18 274 LINIMENTS, LOTIONS, ETC. [817. Liniment of Carron Oil, Aconite, etc.] R. Liquoris Calcis, Olei Lini, aa f^ss; Tincturas Aconiti foliorum, Tincturas Opii deodoratas, aa f 3ij ; Liquoris Plumbi Subacetatis f 3j. Fiat linimentum. A very efficient application to a recent burn or blister, or any erythematous condition of skin. L. C. Heyl. 818. Gum and Molasses Mixture. E. Pulveris Acacias iiij ; Pulveris Tragacanthas ,?j ; Tere simul, et adde gradatim — Aquas fix ; Syrupi Fusci f §ij. Misce. Signa. — Apply over the burnt surface. Dr. T. H. Bache furnishes this, as the formula used in the Pennsylvania Hospital. By some of the surgeons this mix- ture is highly prized in the treatment of burns and extensive scalds. 819. Lotion of Permanganate of Potassa. R. Potassas Permanganatis 3ss: Aquas Oj. Solve. Under the name of "Condy's Fluid" a solution of the per- manganate has been extensively employed in the London hos- pitals in cases of burns, ulcers, and extensive suppurating surfaces, with relief to the pain and a total prevention of any fetor. 820. Liquid Deodorant. R. Spiritus Camphoras, Tincturas Myrrhse, aa f 3iij ; Linimenti Saponis f 3ij ; Acidi Acetici Grlacialis "ixx ; Olei Picis Liquidas fjj. Misce. This preparation, properly diluted, is an excellent applica- tion to sloughing or gangrenous parts, in consequence of its 275 deodorizing properties. It is also of service in cases of diar- rhoea or dysentery, for purifying the air of the chamber. A teaspoonful added to each liquid stool is sufficient to remove the odor, especially if a towel moistened with the lotion be waved for a few minutes in the room. T. Skinner. 821. Lotion of Goulard's Extract and Camphor. R. Liquoris Plumbi Subacetatis f3j ; Spiritiis Camphors f^iij ; Aquae Oj. Fiat lotio. This compound is much recommended by some of the French surgeons. Applied by means of lint to old ulcers and burns. 822. Another Form. R. Confectionis Kosae Ij ; Mellis, Liquoris Plumbi Subacetatis, aa f^ss; Tincturae Opii ffUx. Misce. Signa. — Applied to painful venereal ulcers, and to chancres after the use of lunar caustic. 823. Lotion of Chloride of Zinc. R. Zinci Chloridi gr. ij ; Aquae destillatae fgj. Misce. Signa. — Applied on lint to chronic and indolent ulcers. Hancke. [824. Lotion of Potassa and Hydrocyanic Acid.'] R. Potassae Fusae gr. v; Acidi Hydrocyanici diluti fllxl ; Aquae Kosarum f|j. Misce. Signa.— Sponge the parts night and morning. In the itching pain of chronic eczema. McCall Anderson. 825. Lotion of Sulphuret of Potassium. R. Potassii Sulphured 3ij ; Aquse Oj. Solve. 276 This lotion proves almost magical in its effects in cases of pityriasis. It may be applied with a brush or sponge. J. ISTeill. 826. Lotion of Sulphuret of Potassium, Lime-water, etc. R. Potassi Sulphureti 3ss; Saponis 3j ; Alcoholis f^iv ; Tincturas Myrrhae f^ss; Liquoris Calcis Oj. Fiat mistura secundum artem. Signa. — To be applied to the head night and morning, in tinea capitis. The hair must be shaved previous to its employ- ment. 827. Lotion of Phosphoric Acid. R. Acidi Phosphorici Glacialis 3j ; Aquae destillatae f^viij. Fiat solutio. • Dr. Lentin, a German physician, has employed this solution on compresses applied to ulcers situated over carious bones. Spillan's Supplement to the British Pharmacopoeias. 828. Lotion of Corrosive Sublimate, etc. R. Hydrargyri Chloridi Corrosivi 5j ; Aquas f£vj. Solve et adde — Ammonise Muriatis 3ij ', Potassas Nitratis ^ss. Fiat lotio. Principally used as a wash in itch. Good's Study of Med., vol. iv. 829. Yellow Wash. R. Hydrargyri Chloridi Corrosivi gr. j ; Liquoris Calcis f|j. Fiat solutio. For ordinary purposes, one grain to the ounce will be suffi- cient. In phagedenic and venereal ulcers. LINIMENTS, LOTIONS, ETC. 277 830. Black Wash. R. Hydrargjri Chloridi Mitis 3j ; Liquoris Calcis f^iv. Misce. Signa. — The bottle to be well shaken before using. This prescription is used in the same cases as the other. The red oxide in that, and the black oxide of mercury in this, are precipitated by the lime-water. They are sometimes administered in the form of injections in gleet and gonorrhoea. 831. Lotion of Cyanide of Potassium. R. Potassii Cyanidi gr. xij ; Misturae Amygdalae f^vj. Fiat lotio. Id lichen, and other chronic eruptions. 832. Liniment of Chlorine. R. Aquae Chlorinii f 3j ; Olei Olivae f j§j. Fiat linimentum. Applied externally to itch, herpes, and tinea capitis. Dunglison's New Remedies, 6th ed., p. 195. 833. Lodine Liniment. R. Linimenti Saponis f ,lj ; Tincturae Iodinii f3j. Misce. 834. Creasote Liniment. R. Creasoti t^x. Olei Olivae fSj. Fiat linimentum. In herpes, etc. 835. Creasote Lotion. R. Creasoti n^x; Aceti f 3ij ; Aquae destillatae f^ij. Fiat lotio. Applied in phagedenic ulceration. 278 836. Camphorated Oil. R. Cainphoras Ej ; Olei Olivas f liv. Fiat solutio ; tunc adde — Olei Terebinthinas f 5ss. Misce. Signa. — To be applied by rubbing with a piece of flannel. Used in deep-seated rheumatic pains. 837. Stokes' 's Liniment. — Linimentum Album. R. Olei Terebinthinas f^iij ; Olei Limonis f 3j. Misce, et adcle, secundum artem — Vitellum unius ovi ; Aquas Kosas f ^iij ; Acidi Acetici f^ss. Tere simul. A stimulating liniment having been much prescribed in Baltimore under the above name, the College of Pharmacy of that city has adopted this formula. It is an efficient prepara- tion. 838. Liniment of Cantliarides and Camphor. R. Tinctures Cantharidis f^iv. Camphoras ^ss. Misce. Signa. — To be rubbed on the parts affected. In paralysis. 839. Liniment of Camphor, Carbonate of Ammonia, Amber, etc. R. Spiritus Camphoras f^iv ; Ammonias Carbonatis 3ss ; Olei Juniperi, Olei Succini, aa f3ij. Misce. To be employed in like manner, and in the same cases as the former. 840. Liniment of Camphor and Acetic Acid. R. Spiritus Camphoras f^iij ; Acidi Acetici f^j. Fiat embrocatio. To be applied to bruises, rheumatic parts, etc. LINIMENTS, LOTIONS, ETC. 279 841. Liniment with Ammonia and Olive Oil; vulgo, Volatile Liniment. R. Olei Olivas, Aquas Ammonige, aa f *j. Misce. Applied to the neck in inflammation of the throat. 842. Liniment of Ammonia and Tartarized Antimony. R. Linimenti Ammonias f^j; Antimonii et Potassas Tartratis 5j. Misce. Applied to indolent tumors, and other swellings. 843. Liniment of Oil of Amber, etc. R. Olei Succini f 3ij ; Olei Olivae f Iss ; Tinctures Opii f3ij ; Spiritus Yini Gallici f Jiij. Fiat linimentum. Signa. — To be rubbed between the shoulders. In pertussis. [844. British Oil] R. Olei Terebinthinas, Olei Lini, aa f^viij ; Olei Succini, Olei Juniperi, aa f ^iv ; Petrolei Barbadensis f ^iij ; Petrolei Americani f^j. Misce. An active rubefacient in sprains, etc. [845. Liniment for Scabies.] R. Petrolei, Alcoholis, aa f ^j ; Balsami Peruviani f3j ; Olei Eosmarini, Olei Lavandulae, aa tt^xv. Misce. To be applied several times daily, after bathing with soap and hot water, in cases of delicate skin. Hebra. 280 [846. Sulphuretted Soap Liniment^ R. Potassii Sulphur eti jfiij ; Saponis ^xij ; Aquas q. s. Misce cum calore ; dein adde — 01 ei Olivas f ^xij ; 01 ei Origani f3j. Misce. A very efficient liniment for itch and other parasitic skin disease. Jadelot. 847. Liniment of Oils of Cloves, Amber, and Olives. R. Olei Caryophylli, Olei Succini rectificati, aa ^ss ; Olei Olivas 3j. Tere simul. Used as an embrocation in hooping-cough. Eoche. 848. Liniment with Nux Vomica. R. Tincturas Nucis Yomicas f Ej ; Aquas Ammonias f3ij. Misce. This is applied by friction, in paralytic and nervous diseases. Magexdie. 849. Anti-psoric Lotion of Dupuytren. R. Potassii Sulphureti ^iv ; Aquas Oj ; Acidi Sulphurici diluti f 3iv. Misce. Signa. — To be applied two or three times a day on the parts covered with pustules, and with this treatment the simple bath is conjoined. 850. Compound Opiate Liniment. R. Tincturas Opii, Spiritus ^Etheris Sulphurici, Ed.; Spiritus Camphoras, aa f 3ij. Fiat embrocatio. Signa. — To be applied to rheumatic parts. Also, in odontalgia, pain in the region of the ear, etc. 281 851. Another Form. R. TincturaB Opii, Spiritus CamphoraB, TincturaB Cantharidis, iEtheris, aa f^ss. Fiat embrocatio. Useful in intercostal and other pains. S. Ashwell. 852. Liniment of Opium, Subacetale of Lead, etc. R. Olei Olivasfsij; TincturaB Opii f 3ij ; Liquoris Plunibi Subacetatis flss. Misce. 853. Compound Chloroform Liniment. R. Chloroformi, iEtheris, Spirit"ds CamphoraB, TincturaB Opii, aa f 3j ; TincturaB Capsici f 3ss. Misce. This forms an excellent embrocation for rheumatic pains, sprains, etc. 854. Liniment of Petroleum, Camphor, etc. R. Petrolei Barbadensis, f oj ; CamphoraB iss ; Alcoholis n^xl. Fiat linimentum. Powder the camphor by adding the spirit, and then mix the whole in a mortar. [855. Liniment of Origanum, Camphor, etc.~\ R. Alcoholis Oj ; Olei Olivse fsiij ; Olei Origani f^iij ; TincturaB CamphoraB f 3 iij ; Olei Britannici (Formula 844) fgj. Misce, et fiat linimentum. A very efficient anodyne and stimulant application for bruises, sprains, etc. L. C. Heyl. 282 Glycerin. This principle, which is demulcent and antiseptic, forms a very useful addition to lotions and gargles. It has been used extensively by Mr. Startin, surgeon to the London Cutaneous Institution, and he has published several formulas for its employment. Two of them are subjoined, viz: — 856. Lotion of Borax and Glycerin. R. Sodas Boratis 3ss ; Aquas Eosas flvijss; Glycerinas f^ss. Fiat mistura. Used for chapped hands, fissures of the lips, sore nipples, and irritation of the skin of any kind. Stabtix 857. Lotion of Ammonia, Glycerin, etc. B. Spiritus Ammonias Aromatici f^j ; Glycerinas f ^ss ; Tincturas Cantharidis f 5j ; 1 Aquas Eosmarini f^vij. Misce. Signa. — To be used with a wet hair-brush once or twice a day. Employed for alopecia following fevers, or for falling off of the hair, dryness or want of action of the scalp, thinness of the hair, etc. Staetik. [858. Glycerin Cream.'] B. Glycerinas, Saponis Mollis puri, Aquas Lauro-cerasi, aa f ^j. Misce. For chilblains, chaps, and excoriations. P. Squiee. [859. Liniment of Glycerin and Camphor.'] R. Glycerinas f Ij ; Camphoras Iss; Alcoholis f^ss. Misce secundum artem. For superficial burns, irritable condition of the skin. P. Sqttiee. 1 When aromatic waters are prescribed which are not officinal, the com- pounder can readily prepare them by 'rubbing two drops of the essential oil with a few grains of carbonate of magnesia and a fluidounce of water, and then filtering the solution through bibulous paper. LINIMENTS, LOTIONS, ETC. 283 [860. Lotion of Cantharidine and Castor Oil] R. Cantharidine gr. j ; Athens Acetici f 3ij ; Solve et dein adde — Alcoholis f^iij ; Olei Eicini f ij ; Olei Lavandulae tt^xv. Misce. For baldness ; to be applied daily to the scalp, which is to be thoroughly washed with soap and water every few days, to prevent the accumulation of the cantharidine. This pre- paration is known as the " Linimentum Crinale." P. Squiee. [861. Lotion of Quinia, Castor Oil, etc.'] R. Quiniae Sulphatis gr. xx; Alcoholis f 3ij ; Solve et adde — Olei Eicini f £iv ; Aquae Ammonias f 3iij ; Tincturae Cantharidis f 5ij. Misce. A very successful application in alopecia, or falling out of the hair from any cause ; to be used with the same precaution as the last formula. Any essential oils may be added to give it the odor which may be desired. ■ W. B. Smith. 862. Glycerin Lotion. R. GrlycerinaB f 3ij ; Aquae Eosae f^ij. Misce. This is an emollient and soothing lotion, useful in erythema, chaps, excoriations, etc. — Druggists' Circular. 863. Lotion of Morphia and Glycerin. R. Morphiae Acetatis gr. iij ; Glycerinae f^j. Solve. This is an elegant mode of preparing an anodyne lotion, the quantity of the salt varying with the indications of the case. The salts of nearly all of the alkaloids are soluble in 284 LINIMENTS, LOTIONS, ETC. glycerin, but the bases, or pure alkaloids, are insoluble in this fluid. 864. Lotion of Lead-water and Glycerin. R. Liquoris Plumbi Subacetatis f 5j ; Glycerinas f 3iij ; Aquae f ^vijss. Fiat solutio. This forms an astringent and sedative lotion, which is valu- able in the treatment of many of the skin diseases. — Loud. Hosp.for Skin Diseases. [865. Lotion of Bismuth^] B. Bismuthi Subnitratis gr. xij ; Hydrargyri Bic'hloridi gr. j ; Tincturas Camphoras ^iij ; Aquas ad f^ij. Misce. For application to chronic eczema, herpes, etc. London Hospital. 866. Lotion of Tannin and Glycerin. B. Acidi Tannici gr. xv ; Grlycerinas f^j. Solve. Used for sore nipples, by applying it to the part with a brush, or on lint covered with oiled silk. Some practitioners prefer a stronger solution, consisting of equal parts, by weight, of tannin and glycerin. 867. Lotion of Green Vitriol. B. Ferri Sulphatis 3j ; Aquas Oj. Fiat lotio. Used in erysipelas, by applying it to the part every two or three hours. Velpeau. 868. Lotion of Borax and Morphia. B. Sodas Boratis §ss ; Morphias Sulphatis gr. vj ; Aquas Eosas f^viij. Fiat lotio. Used in pruritus vulvas. OINTMENTS. 285 Wash the surfaces with soap and tepid water, and dry them before applying the lotion, which is to be done three times daily. C. D. Meigs. 869. Lotion of Sulphite of Soda, etc. R. Sodas Sulphitis, Aluminas Sulphatis, aa 3j ; Aquas Eosas f^vijss. Fiat lotio. To the above a tablespoonful of some flavoring ingredient, as the Eau de Cologne, may be added. Used in acne by washing the part with a linen rag dipped in the solution twice or thrice a day. Staetin. 870. Substitute for Aromatic Wine. R. Yini Kubelli (Claret Wine), _ Spiritas Lavandula Compositi, aa f Zv ; Tincturas Opii f^ss; Aquas f^iijss; Acidi Tannici 3ij- Misce. The aromatic wine of the Paris Codex is employed by Eicord and others as a stimulating lotion to buboes and chan- cres, and, when diluted, as an injection in leucorrhcea and gonorrhoea. The above is an efficient substitute for the ori- ginal complex formula, and may be employed in similar cases. F. J. BUMSTEAD. F— OINTMENTS. Ointments are usually prepared by rubbing together the medicinal agent and a sufficient quantity of lard to give a smooth uniform consistence. If intended for immediate use, no better excipient than lard can be found. But if kept on hand for some time, an ointment, thus made, becomes rancid or acrid. To prevent this chemical change, a number of plans have been proposed, the following among others : — 871. Benzinated or Benzoated Lard, As an excipient, is used instead of pure lard. It is prepared by digesting at a moderate heat two drachms of powdered benzoin with a pound of lard. E. Mouchon. 286 OINTMENTS. 872. Plasma, Is the name applied to a mixture of seventy grains of starch and a fluidounce of glycerin. These articles are mixed and gradually heated to 240° F., constantly stirring. This mix- ture is used as a basis for ointments. It dissolves most mate- rials which are soluble in water, and it can be washed readily from tender surfaces. G. F. Shacht. Mr. Startin's formula for a similar preparation is : — R. Tragacanthae electae Iss ; Glycerinas f %j ; Liquoris Calcis f 3ij ; Aquas Kosas q. s. ut fiat gelatina. Misce. This jelly is employed both as a basis for ointments and as an emollient application in various skin diseases. [873. Glycerin Ointment.'] R. Cetacei 3ij ; Ceras albas Jss ; Olei Amygdalae flij. Misce cum calore, et dein adcle — Glycerinas f^j. Et misce celeriter. An admirable emollient for chaps and excoriations. P. Squire. [874. Spermaceti Ointment.] R. Cetacei 5v; Cerae albas 3ij ; Olei Amygdalae f Sijss vel q. s. Fiat ungnentum. A cooling application to burns, or excoriations, or irritable ul cers. — British Pharmacopoeia. 875. Ointment of Red Precipitate. R. Hydrargyri Oxidi Kubri 3j ; Terebinthinas Yenetas 3j. Misce. This preparation is applied to indolent sores, and is thought by some practitioners to be a specific in itch. OINTMENTS. 287 876. Iodine Ointment. R. Iodinii gr. iij ; Adipis 3ij ; Fiat unguentum. Used in enlargements, painful joints, nodes, etc. 877. Iodine and Collodion. R. Iodinii, Terebinthinae Canadensis, aa 3j ; Collodii f 3iv. Solve. Signa. — Paint over the diseased part with a brush. This preparation has proved very efficient in the discussion of tumors, swellings, painful joints, etc. It acts as a rubefa- cient, and even as a vesicant if the skin is tender. J. T. Shinn. 878. Ointment of Iodide of Potassium. R. Potassii Iodidi 9j ; Cerati Adipis 3j. Fiat ceratum. Applied to scrofulous swellings when the skin is unbroken. It may also be used for tetter, and kindred eruptions. 879. LugoVs Ointment of Ioduretted Iodide of Potassium. R. Iodinii gr. xij ; Potassii Iodidi 9iv ; Adipis §ij. Fiat unguentum. Used in scrofulous ophthalmia, ulcers, etc. 880. Ointment of Iodide of Zinc. R. Zinci Iodidi 5j ; Adipis 3j. Fiat unguentum. Signa. — A drachm to be rubbed on twice a day. In tumors. Dr. Ure recommends the above as a substitute for the oint- ment of iodide of potassium in glandular swellings. 288 OINTMENTS. 881. Ointment of Iodide of Barium. R. Barii Ioclidii gr. iv; Adipis ij. Fiat unguentum. For scrofulous swellings. Biett. 882. Ointment of Iodide of Cadmium. R. Cadmii Iodidi 3ss; iEtheris nixl. Tere simul, et adde — Adipis ij. Misce, fiat unguentum. Used in cases of enlarged glands, and nodes, and for chronic inflammation of the joints. This does not stain the skin like iodine or iodide of lead, and is not gritty like the ointment of iodide of potassium. A. B. Gakkod. 883. Ointment of Iodide of Iron. R. Ferri Iodidi 3jss ; Adipis %]. Fiat unguentum. 884. Ointment of Iodide of Sulphur. R. Sulphuris Iodidi gr. xxv; Adipis ij. Fiat unguentum. Used in diseases of the skin, acne, eczema, and scabies. Magendie. 885. Ointment of Iodide of Arsenic. R. Arsenici Iodidi gr. iij ; Adipis lj. Fiat unguentum. Used in lepra, impetigo, and other cutaneous affections. Biett. 886. Ointment of Iodine and Calomel. R. Iodinii gr. x; Hydrargyri Chloridi Mitis gr. xv; Adipis ij. The iodine to be first united to the lard, and then the calomel added. MM. Planck and Soubeiran, by whom this ointment is pro- posed, state that these are the only proportions that can be used, without leading to decomposition. OINTMENTS. 289 [887. Ointment of Mercury with Muriate of Ammonia^] B. Ammoniae Hydrochloratis 3j ; Unguenti Hydrargyri §ij. Misce, fiat unguentum. In chronic glandular enlargements. Dupuytren. Ointment of Iodide of Mercury and Morphia. B. Hydrargyri Iodidi Viridis gr. vj ; Morphiae Acetatis gr. viij ; Adipis §j. Fiat nnguentum. Eecommended by the French physicians in glandular swell- ings. The morphia is supposed by them to prevent the un- pleasant effects of iodine when used as an ointment. Pelletan. 889. Ointment of Red Iodide of Mercury. R. Hydrargyri Iodidi Eubri 9j ; Adipis 3Jss. Fiat unguentum. Used to accelerate the cicatrization of inveterate venereal ulcers. 890. Another Form. B. Hydrargyri Iodidi Eubri gr. xv; Adipis Iij ; Olei Limonis t^xx. Fiat unguentum. Employed as a curative application to syphilitic tubercles, chronic ulceration, and venereal eruptions. Its great activity requires caution in its use. Eatier. 891. Compound Ointment of Red Iodide of Mercury. B. Hydrargyri Iodidi Eubri gr. vij ; Potassii Iodidi 9j ; Adipis Ij. Fiat unguentum. Used for the discussion of glandular and other tumors. C. C. HlLDRETH. 19 290 OINTMENTS. 892. Ointment of Ioduretted Iodide of Potassium tuith Opium. R. Iodinii gr. xvj ; Potassii Iodidi 3j ; Tincture Opii f5ij ; Adipis §ij. Fiat unguentum. Applied to scrofulous and other ulcers. Lugol. 893. Ointment of Cyanide of Mercury. R. Hydrargyri Cyanidi gr. xij ; Adipis §j. Fiat unguentum. Used in herpes attended by inflammation and itching. 894. Mercurial Ointment with Camphor. R. Unguenti Hydrargyri gj ; Camphorse 3j- Misce. Signa. — One drachm of this ointment to be rubbed on the inside of the thighs, before the fire. Used for buboes and venereal diseases. Some physicians recommend the warm bath before using the ointment, while others consider it useless. We think the practice occasionally beneficial. The hands of the person rubbing it on should be enveloped in a bladder, or gloves made of oiled silk. B. Ellis. 895. Ointment of White Precipitate, Sulphur, etc. R. Hydrargyri Ammoniati gr. xv; Potassse Nitratis 3ss ; Sulphuris Sublimati 3j. Tere simul et adde — Adipis iij. Fiat unguentum. This ointment has long been celebrated in the cure of itch. Compound Sulphur Ointment. R. Sulphuris Sublimati 3viij ; Hydrargyri Ammoniati §ss ; Hydrargyri Sulphureti Eubri ^ss. Tere simul et adde — ■ Olei Olivae Siv ; Adipis Bbj ; Creasoti rt^xx. Misce. OINTMENTS. 291 This ointment is employed in the London Hospital for Diseases of the Skin, in the treatment of scabies, favus, and ringworm. Staktin. 897. Anti-herpetic Ointment. R. Hydrargyri Sulphatis Flavse 3j ; Tincture Opii f 3j ; Sulphuris Sublimati 3ss; Adipis 3j. Fiat unguentum. In herpes, alternated with the simple water-bath. 898. Sulphur Ointment. R. Adipis fib j ; Olei Bergamii f 3ij ; Sulphuris Sublimati 3viij. Fiat unguentum. Used by friction, three to six drachms at a time, in itch. 899. Mercurial Cerate, R. Unguenti Hydrargyri siv; Cerati Adipis Jx. Fiat ceratum. A dressing for venereal ulcers. Ratiek. 900. Ointment of Cyanide of Potassium and Chloroform. R. Potassii Cyanidi partes x ; Chloroformi Yenalis partes xij ; Adipis partes lx. Fiat unguentum. Eecommended in hemicrania and facial neuralgia. A portion to be well rubbed into the skin over the seat of suffering. Cazenave. 901. Ointment of Belladonna. R. Extracti Belladonnas 3ij ; Glycerinae f 3ij ; Adipis oij. Misce. Employed as a direct application to the neck of the uterus, in cases of rigidity. 292 OINTMENTS. 902. Ointment of Alum, Calomel, etc. B. Hydrargyri Chloridi Mitis 3ij ; Aluminis exsiccati, Plumbi Oxidi, aa ^ss ; Olei Terebinthinae f 5ij ; Unguenti Adipis ijss. Fiat unguentum. This ointment is particularly adapted to tinea capitis. It should be applied every night going to bed, and washed off in the morning. As soon as the child's head is dry, dust it over with powdered starch, which, in the evening, is again to give place to the ointment. The hair must be cut off previous to the application of the ointment. S. Gr. Morton. 903. Ointment of Calomel and Sulphate of Zinc. B. Hydrargyri Chloridi Mitis, Zinci Sulphatis, aa 5ij ; Adipis 3j. Fiat unguentum. Used in the Eoyal Free Hospital, London, in the treatment of condylomata. Y. De Meric. 904. Ointment of Oxide of Zinc. B. Zinci Oxidi 5j ; Adipis Benzoati 3j. Fiat unguentum. This is a mild and very useful ointment for scalds, super- ficial inflammations, ulcers, etc. 905. Kentish 1 s Ointment. B. Cerati Besinae §ij; Olei Terebinthinae f3ij. Fiat unguentum. This preparation has long been celebrated in burns and scalds. Care is requisite to avoid touching the sound skin, for turpentine occasionally inflames it severely. 906. Ointment of Bromide of Potassium. B. Potassii Bromidi gr. xxx; Adipis §j. Fiat unguentum. Used for scrofulous tumors. OINTMENTS. 293 907. Ointment with Goulard's Cerate, Calomel, etc. R. Cerati Plumbi Subacetatis, Cerati Adipis, aa 3ss ; Hydrargyri Chloridi Mitis, Pulveris Opii, aa 3j. Misce. Useful in various cutaneous eruptions. Joseph Parrish. 908. Ointment of Rhubarb, Opium, etc. R. Pulveris Khei gr. x; Pulveris Opii gr. v ; Unguenti Adipis ^jss. Fiat unguentum. In indolent ulcers. 909. Ointment of Tar, and Citrine Ointment. R. Unguenti Picis Liquidae Ij ; Unguenti Hydrargyri Nitratis ^ss. Fiat unguentum. In tinea capitis. [910. Ointment of Coal Tar.'] R. Picis Mineralis 3ij ; Glycerinae purse f 3iij ; Adipis Benzoati (Formula 866) ^jss. Misce, fiat unguentum. For application to chronic eczema. To be melted a little, and rubbed in three or four times daily. Anderson. [911. Ointment of Mercury and Carbolic Acid."] R. Hydrargyri Ammoniati 3j ; Adipis Benzoati (Formula 866), Plasmatis (Formula 867), aa 3yj ; Acidi Carbolici n^xx. Fiat unguentum. In chronic eczema. To be applied three or four times daily. 294 OINTMENTS. [912. Olive Ointment. 1 B. Cerse Flavse ^iv; Olei Olivse f Iviij ; Mellis I]. Emplastri Galbani Compositi siv. Fiat unguentum. This should be melted, strained, and stirred till cold. A stimulant application for indolent ulcers and boils. 913. Ointment of Tar and Opium. B. Pulveris Opii 3ij ; Unguenti Picis Liquidse Ij. Fiat unguentum. For haemorrhoids. 914. Ointment of Oil of Cade. B. Olei Juniperi Oxycedri Pyrolignei Ej ; Olei Anisi gtt. iij ; Adipis 3ij. Fiat unguentum. The oil of cade is an empyreumatic product obtained by the destructive distillation of the Juniperus Oxycedrus. It has proved highly beneficial in many forms of skin dis- ease, especially in eczema and tinea. Devergie. [915. Chloroform Ointment.'] B. Chloroformi 3j ; Adipis Benzoati (Formula 866) ^ij ; Cocci gr. J. Misce, fiat unguentum. For eczema, with burning heat of skin. McCall Anderson. [916. Benzoic Acid and Lead?] B. Acidi Benzoici 3j ; Cerati Plumbi Subacetatis Ij. Misce, fiat unguentum. For application to erythematous affections of the skin, or erosions. OINTMENTS. 295 917. KirklancPs Neutral Cerate. R. Emplastri Plumbi ^iv ; Olei Olivae, Cretae Prseparatae, Acidi Acetici diluti, aa Hij ; Plumbi Acetatis 3jss. The plaster and oil are first to be melted over a gentle fire. The prepared chalk is then to be briskly stirred in, and when the mixture is sufficiently cooled, the acetic acid and acetate of lead are to be added, and the whole stirred until nearly cold. This non-officinal cerate is well adapted to abraded irritable surfaces, and the later stages of burns. 918. Aromatic Compound Sulphur Ointment. R. Potassae Carbonatis 3ss ; Aquae Eosae f Ij ; Hydrargyri Sulphured Eubri Ej ; Olei Bergamii f ^ss ; Sulphuris loti, Adipis, aa 3x. Misce secundum artem. Used in scabies. Bateman's Synopsis. 919. Naphthaline Ointment. E. Naphthalinae 9ij ; Adipis Ej f Fiat unguentum. 'Eecommended by Dr. Lodge in the treatment of itch. Dr. Emery has found it effectual in cases of dry tetter, lepra, and psoriasis. 920. Ointment of Carbonate of Ammonia. R. Ammoniae Carbonatis 3ss ; Unguenti Adipis 3ss. Fiat unguentum. Applied to indolent ulcers of a scrofulous character. 921. Ointment of Verdigris, etc. R. Cupri Subacetatis, Cupri Sulphatis, Hydrargyri Oxidi Eubri aa 3ij 5 Hydrargyri Chloridi Corrosivi 3j ; Adipis Iv. Fiat unguentum. 296 OINTMENTS. This may be spread on lint, and one or two applications will be sufficient to destroy a very large mass of fungous granulations. B. C. Brodie. 922. Ointment of Ipecacuanha. R. Pulveris Ipecacuanhas 3ij ; Olei Olivas f 3ij ; Adipis Sss. Misce, et fiat unguentum. Useful as a counter-irritant. Turnbull. 923. Ointment of Calomel and Tar. R. Hydrargyri Chloridi Mitis 3j ; Unguenti Cetacei, Zonal. 3j ; Unguenti Picis Liquidge ^ss. Fiat unguentum. Used in lepra. A. T. Thomson. 924. Ointment of Creasote and Char coed. R. Creasoti f3ss; Alcoholis J5jss; Carbonis Animalis puriflcati 3j; Unguenti Cetacei, Lond. ^jss. Fiat unguentum. Used in cases of burns and scalds. " For children under five years, the ointment should be weakened by mixing it with four times its bulk of spermaceti ; for children from five to ten years, with twice its bulk of spermaceti; and so on, gradually increasing the strength of the ointment according to the age of the patient." S. Sutro. [925. Ointment of Carbolic Acid and Castor Oil] R. 01. Eicini f^j; Balsami Abietis ^ss ; Cerse Albas 3ij- Misce cum calore, dein adde — Acidi Carbolici liquidi f 3ss. Misce, fiat unguentum. To be used in suppurating surface from burns, chronic ulceration, or wounds. To the above may be added with advantage, sometimes, Zinci Oxidi puri 3j- OINTMENTS. 297 926. Oxide of Silver Ointment. B. Argenti Oxicli 5j ; Unguenti Adipis %j. Fiat unguentum. Used for sore nipples. 927. Ointment of Slaked Lime, Zinc, etc. B. Calcis Hydratis 3j ; Camphoras 9j ; Unguenti Zinci Oxidi ^j. Fiat unguentum. This is the "topique contre acne" of the Hopital S. Louis. 928. Depilatory Ointment. B. Sodas Carbonatis 3ij ; Calcis, 3j ; Adipis Jj. Fiat unguentum. Used in porrigo. Biett. 929. Veratria Ointment. B. Veratrias gr. x ; Acidi Acetici t^x ; Adipis §j,. Fiat unguentum. Veratria has been used externally in neuralgia, in twitching and drooping of the eyelids, and in other nervous disorders, with the most marked success. 930. Veratria and Morphia Ointment. B. Veratrias, Morphias Sulphatis, aa gr. x ; Adipis ^j. Fiat unguentum. Used in incontinence of urine, by rubbing a portion of the ointment on the perineum three times daily. T. Kennaed. 931. Ointment of Nitrate of Silver. B. Argenti Mtratis 3ss ; Adipis loti 3ss. Fiat unguentum. Used to smear over bougies in the treatment of gonorrhoea. Macdonald. 298 OINTMENTS. [932. Ointment of Copper, Lead, and Copal Varnish.'] R. Cupri Sulphatis gr. iij ; Plumbi Acetatis gr. x ; Spiritus Resinae Copal f 3j ; Cerati Simplicis 3ij. Misce, fiat unguent am. An admirable application for chronic piles. L. C. Heyl. [933. Ointment of Opium and Tannin. ,] R. Extracti Opii Aquosi gr. x; Acidi Tannici 3j ; Cerati Plumbi Subacetatis Ij. Misce, fiat unguentum. For piles — to be introduced in quantity about size of a pea within the sphincter. 934. Ointment of Tannin. R. Acidi Tannici 3j ; Grlycerinse «ll ; Adipis Ij. Fiat unguentum. Used for the same purposes as the astringents generally. 935. Ointment of Tannate of Lead. R. Plumbi Tannatis 3j ; Unguenti Aquas Eosas 3J. Fiat unguentum. A sedative and astringent application to sore nipples, chapped surfaces, etc. M. Leon. [936. Discutient Plaster.] R. Olei Lini, Olei Olivae, Plumbi Oxidi Eubri, aa partes equales. Misce secundum artem, fiat emplastrum. For rubefacient and resolvent effect. C. D. Meigs. Powders. Sometimes the practitioner prefers dusting medicinal agents directly upon diseased surfaces, instead of incorporating them OINTMENTS. 299 with lard in the form of an ointment. Hundreds of such formulas might be given, but we limit our selection to a few. 937. Povjder of Verdigris and Calomel. B. Cupri Subacetatis, Hydrargyri Chloridi Mitis, aa 9j. Fiat pulvis subtilissimus. For chancres and indolent ulcers. 938. Poivdered Rhubarb and Ipecacuanha. B. Pulveris Khei, Pulveris Ipecacuanhas, aa 3j. Fiat pulvis. To be dusted on sarcomatous and watery tumors. Ehubarb alone forms an excellent application to indolent ulcers. 939. Powder of Savin and Verdigris. B. Pulveris Sabinae, Cupri Subacetatis, aa 5j- Fiat pulvis. To be dusted on sores accompanied with fungous excres- cences. [940. Depilatory Powder.] R. Sodii Sulphureti 3iij, Pulveris Calcis (non hydrata), Pulveris Amyli, aa 3^. Misce. To be mixed, when required for use, with a little water, applied to the skin, and removed in a few minutes with a wooden knife. For the removal of hair. P. Squire. 941. Powder of Sanguinarina. R. Sanguinarinae Sulphatis 3j. Tere in pulverum. Employed for the removal of venereal warts, by dusting the surface of the warts thickly with the powder, and then applying collodion to retain the powder in direct contact with the skin. 300 CATAPLASMS. G. — CATAPLASMS. 942. Bread- and- Milk Poultice. Remove the crust from a part of a loaf of stale bread, and crumble the bread into a bowl. Pour over it sufficient sweet milk to cover it, and simmer over a fire, occasionally stirring, until the bread is reduced to a pulpy consistence. The poultice is to be applied as warm as the patient can bear it. Water may be substituted for the milk without much if any disadvantage. 943. Flaxseed Meal and Bran Poultice. Take equal parts of ground flaxseed and bran. Pour boil- ing water upon them, and stir constantly until the poultice has a pulpy consistence. In the Northern and Middle States it is customary to use the common flaxseed meal, which contains both the oily and mucilaginous principles ; but in New York city and some other places, the ground oil-cake is preferred. Equal parts of the latter and bran form an elegant poultice. 944. Mush Poultice. This is made by stirring Indian meal, in small quantities, into water kept boiling in a pan, until the whole has acquired the proper degree of consistence. 945. Yeast Poultice. R. Farinae, Ed., Bbj ; Fermenti, Oss. Misce. This cataplasm is useful in stimulating foul ulcers and gan- grenous wounds, and removing the unpleasant odor. It should be made with fresh yeast, and applied warm. 946. Charcoal Poultice. This cataplasm is made by stirring into the common bread- and-milk poultice as much finely-powdered charcoal as it will bear, and then sprinkling upon the surface of the poultice, when ready for application, some more of the powder. It is a very useful application to offensive ulcers ; removing in a short time the fetor, and giving them a more healthy aspect. CATAPLASMS. 301 '947. Slippery Elm Poultice. This poultice is made from the inner bark of the slippery- elm, ground into a fine powder, and moistened with hot water. Cataplasms are also made of carrots or turnips, by simply boiling them to softness, and beating them to a pulpy mass. Either furnishes a good poultice for cancerous and other pain- ful sores. 948. Emollient Cataplasm. R. Lini Farinas, Hordei Farinas, aa partes asquales ; Aquae q. s. ut fiat cataplasma. The water may be warmed if desirable. Applied to inflam- matory tumors. Hotel Dieu. [949. Another Form."] R. Pulveris Lini, Pulveris Foenigrec, aa partes asquales ; Aquas bullientis q. s. ut fiat cataplasma. Applied very efficiently for the evacuation of slow abscesses. 950. Antiseptic Cataplasm. R. Cataplasmatis Emollientis {vide supra, 948) 3viij ; Pulveris Kino, Camphora, aa 3ij. Fiat cataplasma. Applied to unhealthy wounds and ulcers. Hotel Dieu. 951. Resolvent Cataplasm. R. Cataplasmatis Emollientis {vide supra, 948) §iv; Plumbi Acetatis 3j ; Ammonias Muriatis 3ss. Fiat cataplasma. Applicable to tumors that require gentle stimulation. Batier's Formulary. 952. Cataplasm of Common Salt, etc. R. Lini Farinas, Micas Panis, aa partes asquales. Misce, dein adde gradatim — Liquoris Sodii Chloridi saturati q. s. ut fiat cataplasma. To be applied to indolent strumous swellings, and enlarge- ments of the joints. When it produces irritation or inflam- 302 BATHS. mation the common bread-and-milk poultice must be substi- tuted; and the other reapplied when circumstances permit. 953. Iodine Cataplasm. E. Tincturae Iodinii f sss ; Lini Farinae 3J ; Avenge Farinas §iij ; Aquae q. s. ut fiat cataplasma. Applied to indolent ulcers (especially those of a scrofulous character), and to tumors of the same class. H. — BATHS. The ordinary application of cold, tepid, and shower-baths, is too well known to require any particular notice. The hot bath should be of a temperature of 93 to 96 degrees of Fahren- heit. It is designed to alleviate general or local irritation, and to induce repose and sleep. It is especially adapted to fevers with deficient capillary circulation, rheumatism, her- petic eruptions, paralytic affections, etc. The lower tempera- ture is best adapted to cutaneous complaints, and to bring on relaxation of the skin during febrile irritation ; the warmer temperature is suited to paralysis; and, as a general rule, more heat is desirable to act upon deep-seated than on super- ficial diseases. Vapor Baths are produced by the evaporation of boiling water in a suitable apparatus. They are used, like ordinary warm baths, in rheumatic and cutaneous affections, and in every case wherein profuse perspiration is desirable. They are avoided in persons laboring under pulmonary or cardiac disease, and in exhaustion from any cause. Local Baths are admirably adapted to parts which are swelled and painful, and may consist of tepid water only, or their strength may be increased by the addition of saline, emollient, narcotic, or stimulant substances. Among these salt and mustard are preferable. 954. Sulphurous Water, or Artificial Bareges Bath. R. Potassii Sulphur eti Bbj ; Aquae Cong. xxx. Solve. In cutaneous eruptions. BATHS. 303 955. Sulphur eo- gelatinous Bath. R. Potassii Sulphureti siv ; Aquae Cong. xxx. Fiat solutio et adde — ■ Ichthyocollae ft>j. In Aquae bullientis ft>x solutae. This bath, according to Dr. Green (Diseases of the Skin, p. 240), " is preferable to the artificial Bareges bath, as it is neither irritating nor apt to occasion feverishness, which the common sulphurous water-bath is. A cheaper and not less efficacious gelatine may be procured by dissolving from a pound and a half to two pounds of parchment-clippings in water by long boiling, or by using a neat's or a calf's foot for the purpose." 956. Emollient Bath. R. Glycerinae 3j ; Pulveris Tragacanthae 3j ; Aquae tepidae Cong. xv. Misce. Useful in prurigo eczema, lichen, impetigo, and other forms of cutaneous disease. Hosp./or Skin Diseases. 957. Nitro-muriatic Acid Bath. R. Acidi Nitrici f.iij ; Acidi Hydrochlorici f ^iij ; Aquae Cong. ijss. Misce. Used for syphilitic affections, and various obstinate skin diseases. St. Geobge's Hosp. 958. Corrosive Sublimate Bath. R. Hydrargyri Chloridi Corrosivi 3ij ; Aquae tepidae Cong. xxx. Solve. Prescribed by the French physicians in syphilitic affections, when it is desirable to avoid the action of the medicine on the stomach. This plan is seldom resorted to, on account of the great risk of employing corrosive sublimate in such large quantity. 304 BATHS. 959. Alkaline Baths. R. Potassas Carbonatis Impuras 3viij ; Aquae tepidas Cong. xxx. Solve. For promoting desquamation from the skin, and to allay itching in various forms of prurigo. 960. Ioduretted Baths. No. 1. No. 2. No. 3. 3ij. 3iij. 3iv. 3iv. 3v. 3viij. ' ^vj. Ovj. fivj. R. Iodinii Potassii Iodidi Aquas destillatas Fiant solutiones. One of these solutions, according to the strength required, is added to a tepid bath in a wooden tub. For children, the drachms may be reduced to scruples. Used in scrofula. 961. Artificial Harrowgate Bath. R. Sodii Chloridi Ibij; Magnesias Sulphatis 3iij ; Potassii Sulphureti Bbj ; Aquas Cong. xxx. Solve. I.— FOMENTATIONS. Fomentation is a more restricted mode of applying fluids to the surface of the body, and is best accomplished by means of a sponge, flannel, or soft cloth. To be efficacious it should be often repeated. 962. Stimulant Fomentation. R. Yini Portensis Oij ; Mellis liv. Misce. This is an active fomentation, adapted to parts in a low state of vitality. Eatiee. 963. Saponaceous Fomentation. R. Alcoholis Oij ; Saponis 3j. Misce. A resolvent in indolent tumors and in sprains. Batter. FUMIGATIONS. 305 964. Anodyne Fomentation. R. Extracti Opii 3j ; Aquae Oj. Solve. For painful affections of the joints, as chronic rheuma- tism, etc. Batter, 965. Fomentation of Bitter Sweet and Poppy. R. Dulcamaras ^ij ; Papaveris iij ; Aquae ferventis Oj. Fiat infusum. Employed as a soothing application to irritable surfaces, 966. Mustard Fomentation. R. Sinapis Farinae ^iv; Aquas ferventis Oj. Misce. By wetting cloths in this fluid and applying them to the skin, irritation may be prolonged to any requisite degree. 967. Tobacco Fomentation. R. Tabaci 3ij ; Aquae ferventis Oj. Misce. Employed in psora, but is apt to produce nausea and vomit- ing. Its use requires great care. K— FUMIGATIONS. Fumigations are for the most part used to purify infected air by absorbing or otherwise counteracting deleterious gases. They are also employed in diseases of the skin, and may be sometimes substituted for a local bath. 968. Fumigation with Sulphur, Cinnabar, and Iodine. R. Sulphuris Praecipitati 3iij ; Hydrargyri Sulphureti Kubri 9ij ; Iodinii gr. x. Fiant pulveres vj. 20 306 FUMIGATIONS. One of the powders to be used in the following manner : " If the disease is seated on the limbs, a tin case, or even a common jar, should be procured. A heated iron is to be placed at the bottom of this apparatus, with a grating above it to protect the foot or hand. One of the powders being placed on this heated iron, the limb is to be instantly put into the bath, the top of which should be covered over, to prevent the vapor from escaping. The limb may be con- tinued in the bath from fifteen to 'twenty minutes, according Used in lepra. T. H. Burgess. >. Mercurial Vapor Bath. R. Hydrargyri Oxidi Nigri 3j ; vel Hydrargyri Oxidi Kubri 3j ; vel Hydrargyri Sulphureti Rubri 3j- Place the mercurial upon a plate suspended over a spirit- lamp ; and suspend a small vessel containing boiling water over a second spirit-lamp. Both are to be deposited under a chair, on which the patient is seated, having an oil-cloth or a coverlet thrown around him in such wise as to envelop the apparatus, chair, and his entire person, excepting the face. When the lamps are lighted,, mercurial fumes and steam are both generated, and mercury is thus directly applied to the whole surface of the body in a moist state. The bath should not continue longer than twenty minutes, when the patient should be rubbed dry and be removed to bed. This plan of medication is particularly serviceable in the treatment of constitutional syphilis, and obstinate skin dis- eases. L. Parker. 970. Chlorine Fumigation. R. Calcis Chlorinatse 3iv ; Aquas f'lviij. Misce, et adde gradatim— Acidi Sulphurici 3j- The irritant properties of chlorine preclude its employment in disease by inhalation, except in occasional cases of aphonia, but it is often used for disinfecting purposes. A small quan- tity may be set free in a sick-chamber, or the ward of an hospital, to remove offensive odors. DISINFECTANTS. 307 L. — D IS INFECT ANTS. Under this head are included all substances which have the power of acting upon noxious effluvia in the atmosphere, and, either by combining with them chemically, or destroying the vitality of the germs of disease, neutralizing their influence upon living beings. Apart from mere medicinal agents, as sold in the shops, there are natural and artificial means of purifying the atmosphere of more importance, and in themselves essential, without which all other means are futile. Yentilation, drainage, sunlight, and cleanliness are so intimately connected with pure air that they suggest themselves as necessary in all cases where disinfect- ants are needed. In hospital and private practice these con- ditions should be thoroughly looked into, and it will be found that seldom will chemical disinfectants be required if proper attention be paid to having a well regulated supply of fresh air; the rapid removal by sewage of all refuse matters, either in the form of discharges from patients or decaying animal or vegetable matters of any sort ; a full supply of sunlight ; the. immediate removal from the person and from the room of all discharges of secreta or excreta, the protection of the bed against absorption of foul liquids, and the frequent change of clothing on the person and on the bed ; the subjection of such clothing to a high heat in an oven, say 220° F., with their subsequent exposure to the direct rays of the sun ; and fre- quent ablutions with soap and water of the patient's body, when practicable. The simple means of disinfection thus indicated should be aided by the use of purifying agents which will not in themselves contaminate the air. Charcoal, recently burned, placed about a room ; lime, in the form of whitewash, applied to the walls, especially where rooms are to be purified after the removal of patients with infectious diseases; clothes steeped in a strong solution of permanganate of potassa and hung about the bed, are all efficient means of preserving the freshness of the atmosphere in rooms containing patients with diseases of an offensive character, and in themselves means attended with no disagree- able accompaniments. The preparations of chlorine, chloride of lime placed in saucers with a little dilute sulphuric acid poured over it, or Labarraque's solution of chlorinated soda placed in vessels around the room, will have the desired effect, and may be necessary in extreme cases attended with profuse fetid dis- 308 DISINFECTANTS. charges ; but they are so offensive themselves that they often disgust the patient, and may, in some instances, act as Aber- nethy considered all disinfectants to do in his day, by driving the patient out of the room. The importance of preventing exhalations from the excreta of patients is now well recognized, and even where they can be removed rapidly, it is very desirable that the vessels into which they are passed should be previously purified by some of the various disinfectants mentioned below. In some cases, however, the physician may desire to inspect the discharges unchanged by any chemical agent, in which case he should never forget to see that they are not retained in the patient's room, which is not unfrequently done, especially in the case of children's napkins, by people of otherwise good sense. They should be placed, if possible, out of doors, or, at any rate, where there is good ventilation. Carbolic acid and creasote, while they are powerful anti- septics, have scarcely any claims to the place of disinfectants; their power of destroying the effects of putrefaction extending little, if any, beyond masking the smell by another, which, to many persons, is equally disagreeble. Sulphurous acid is applicable only to the disinfection of unoccupied places, and mainly useful in destroying the poison of contagious diseases. Fumigations with balsamic substances, the burning of sugar or coffee, the diffusion of volatile perfumes, and all similar methods of deodorizing, have no influence whatever in neutralizing poisonous effluvia, merely covering the smell and concealing the presence of noxious matters; so that, if relied upon at all as a substitute for efficient disinfectants, they become rather dangerous than useful. A number of combinations have been suggested of sub- stances having the power of destroying effluvia. M. Bonjean directs charcoal, well powdered, two pounds, sulphate of iron one pound, to be mixed ; of which two or three tablespoonfuls are to be placed in the chamber vessels used by the sick. Dr. Procter has great confidence in iodine placed in open saucers about the room, or gently volatilized by moderate heat. Burnetts fluid consists of a saturated solution of chloride of zinc. Collinses disinfecting powder contains dry chlorinated lime two parts, burnt alum one part ; used dry or moistened with water. Condy's fluid is a solution of the alkaline permanganates. DISINFECTANTS. 309 Mlermann's deodorizing fluid consists of a solution of the perchloride of iron and the chloride of manganese. Ledoyerts disinfectant is a solution of two troyounces of nitrate of lead in a pint of water. Siret's disinfecting compound (No. 1) is a mixture of sul- phate of lime 53 lbs., sulphate of iron 40 lbs., sulphate of zinc 7 lbs., and peat charcoal 2 lbs., made into balls. Siret's compound No. 2 contains sulphate of iron 20 parts, sulphate of zinc 10 parts, oak bark, powdered, 4 parts, tar and oil each one pint, made into balls. Used for deodorizing cesspools. Professor R. E. Rogers advises a mixture of quicklime and sulphide of iron. The U. S. Army disinfectant consists of a powder of common salt and binoxide of manganese in packages, upon which is to be poured in a shallow dish a solution of sulphuric acid and water. The exact proportions and details are found in the last edition of Parrish's Practical Pharmacy. BOOK III. OP DIETETIC PREPARATIONS, AND POISONS. DIETETIC PREPARATIONS AND BEVERAGES EOR THE SICK. The importance of an acquaintance with those preparations of diet peculiarly designed for the patient during disease and convalescence, is so obvious that it requires little or no com- ment. It was remarked by the late Dr. Rush, in his lectures, that a physician should spend six months in a kitchen before entering upon his practical career. As the medical attendant, therefore, is called upon frequently to give directions and rules for preparing the diet of the sick, we have inserted a few formulas for those articles which are in daily use. How- ever apparently trifling such a class may appear, the physi- cian will find that an attention to it will place the patient more completely under his own control, and inspire greater confidence in the relations and attendants. The rules to be observed in giving nourishment to the sick, will generally present themselves ; but there is one in particular which should not be overlooked. In all low diseases, the nurse should be directed never to give too much at once, but fre- quently to repeat a small proportion. The lapse of a very short time without food will frequently, in cases of great prostration, reduce the patient very low, and may endanger his life. The rule is not intended to be applied to those chronic derangements of the digestive functions which are to be re- medied principally by a regulation of diet, and in which the old adage, "a little and often," has too frequently, we are con- vinced, been perniciously advised. 971. Barley Water. Take of Pearl Barley 2 ounces, Boiling Water 2 quarts. Before adding the boiling water, let the barley be well washed. Then boil it to one- half, and strain the liquor. A little lemon-juice and sugar may be added, if desirable. To be taken freely in inflammatory diseases. 314 DIETETIC PREPARATIONS. 972. Rice Water. Take of Eice 2 ounces. Let it be well washed, and add to it — Water 2 quarts. Boil for an "hour and a half, and then add as much sugar and nutmeg as may be required. To be ^aken freely. Eice, when boiled for a considerable time, assumes a gela- tinous form, and, mixed with milk, is a very excellent diet for children. It possesses, in some measure, a constipating property, which may be increased by boiling the milk. 973. Flaxseed Tea. Take of Flaxseed . . . . . . 1 ounce, Boiling Water . . . 1 pint. Pour the boiling water on the unbruised seed. Cover the vessel, and stand it near the fire for an hour or two. The seeds must not be crushed or boiled, lest the oil in the inte- rior should be extracted. Having strained the infusion, add to it a little lemon-juice, if no contra-indicating circumstances exist. Flaxseed tea is a mild demulcent, and is much used in dis- eases of the throat, chest, and urinary passages. 974. Toast Water. Cut a slice, half an inch thick, from a loaf of stale bread, re- move the crust, and carefully toast the slice on both sides. Place the toast and a small piece of orange or lemon-peel in a suitable vessel, add- a pint of boiling water, cover the vessel, and, when cold, strain off the water. This forms an agreeable drink, in febrile diseases. 975. Apple Water. Slice two large apples, and pour over the slices a pint of boil- ing water. Infuse for an hour, decant, and sweeten with white sugar. 976. Currant Jelly Water. Boil together equal weights of white sugar and the juice of ripe currants, until the mixture gelatinizes by cooling, as shown by dropping a few drops on a cold plate. Eemove the scum, and form the jelly in suitable vessels. DIETETIC PREPARATIONS. 315 A tablespoonful of this jelly, diffused through half a pint of cold water, makes a delightful acidulous drink, which is much relished by invalids. 977. Mucilage of Gum Arabic. As an article of diet, the proper proportions are an ounce of Gum Arabic to a pint of boiling water. The solution is allowed to cool before it is used. Gum Arabic is very nutritive, and life can be sustained on it alone for some time. 978. Bran Tea. Take of Fresh Wheat Bran .... . 1 pint, Water . . . . . 3 quarts, Boil to two quarts, strain off the liquor, and add sugar, according to the taste of the patient. 979. Sage Tea. Take of The dried leaves of Sage . . . half an ounce. Boiling Water 1 quart. Infuse for half an hour, and then strain. Sugar and lemon- juice may be added in the proportion required by the patient. In the same manner, balm and other teas may be made. These infusions form very agreeable and useful drinks in fever, and their diaphoretic powers may be increased by the addition of sweet spirit of nitre or antimonial wine. 980. Infusion of Malt. Take of Ground Malt . 1 pint. Scalding Water . 3 pints, Infuse for two hours, and strain off the liquor, to which may be added sugar or lemon-juice, if required. This was a favorite preparation with the late Dr. Joseph Parrish, in inflammatory fevers. 316 DIETETIC PREPARATIONS. 981. Lemonade. Take of Fresh Lemon Juice . ... 4 ounces, Fresh and very thin Peel of Lemon . half an ounce, White Sugar 4 ounces, Boiling Water . . . . .3 pints. Let them stand until cold, then strain off for use. When employed in fevers, a little nitrate of potassa or sweet spirit of nitre may be added. R can be further diluted to the taste of the patient. When fresh lemon-juice cannot be procured, an excellent lemonade can be prepared from lemon syrup made as follows : Dissolve ten drachms of tartaric or citric acid and eight pounds of loaf sugar in a gallon of water. Then rub twenty drops of fresh oil of lemon with a portion of the syrup, and afterwards carefully mix it with the remainder. Lemonade, when freely taken, sometimes produces pain in the bowels. It must, therefore, be used with some reserve as a daily drink. 982. Oatmeal Gruel, Eub two ounces of oatmeal into a paste with a little water, and gradually add a quart of boiling water. Let the whole boil for fifteen minutes, stirring frequently. Add a little salt, remove from the fire, and sweeten to the taste. If no reason to the contrary exists, the flavor of the gruel is much improved by adding some nutmeg, with wine or brandy, or a few raisins. 983. Gornmeal Gruel. Indian meal gruel is made in the same manner as oatmeal gruel. It is necessary, however, to boil it a few minutes longer. 984. Rice Flour Gruel. Take of Ground Eice . . . 1 ounce, Cinnamon ..... . 1 drachm, Boiling Water . 1 quart. Having rubbed the rice flour into a paste with a portion of the water, add the remainder gradually, and boil for forty minutes, adding the aromatic near the conclusion. Strain and sweeten. Wine may be added, if necessary. DIETETIC PREPARATIONS. 317 985. Panado. Take of AT beat Bread . .... . 1 ounce, Cinnamon .... . 1 drachm. Water . . 1 pint. Boil them until well mixed, then add a little grated nutmeg and sugar. Wine or butter may also be added, if de- sirable. Compound Salep Powders (Castanelloh Powders). Take of Salep, Tragacanth, Sago, each four ounces ; Cochineal thirty grains; Prepared Oyster-shells one ounce. Mix carefully, and divide into powders of a drachm each. Stir one of these powders into a pint of milk, and boil them together for ten or fifteen minutes. To be drunk freely in dysentery and diarrhoea. These are the dysenteric powders of Dr. Castanello. A somewhat analogous preparation, sold under the same name, is prepared as follows : — Take of Gum Arabic, Tragacanth, Arrowroot, Sago, Tapioca, each two drachms. Mix them well together, and boil in a pint of milk, flavored with nutmeg or cinnamon. Used as a diet in dysentery, diarrhoea, etc. etc. 987. Racahout des Arabes. Take of Dried Cocoa, in powder Jiv; Potato- Starch (or Arrowroot), Eice Flour, each 5x; Sugar 3xv ; Vanilla 3ss. Mix carefully. 318 DIETETIC PREPARATIONS. This is prepared for the sick by pouring half a pint of boil- ing milk on a tablespoonful of the powders, and boiling for a few minutes. 988. Diabetic or Bran Bread. Boil two or three quarts of wheat bran in two successive waters for ten minutes, each time straining through a sieve, and wash well with cold water until the water runs off clear. Squeeze the bran as dry as possible in a cloth, spread it thinly on a dish, and dry it in a slow oven. When perfectly dry, grind it in a mill, and sift it through a fine sieve. Take six ounces of this ground bran, six eggs, three ounces of butter, and one pint of milk. Mix the eggs with a part of the milk, and warm the butter with the other portion. Then stir the whole well together, adding a little nutmeg or ginger, or any other agreeable spice. Immediately before putting into the oven, stir in seventy grains of bicarbonate of soda; and then six drachms of dilute hydro- chloric acid. Bake for an hour, or until thoroughly done. As thus prepared, bran bread contains but a small amount of starchy matter. It has the further advantage of being quite palatable. Camplin. • 989. Sago. Take of Sago 2 tablespoonfuls, Water 1 pint. Boil gently until it thickens, frequently stirring. Wine, sugar, and nutmeg may be added, according to circum- stances. 990. Tapioca Jelly. Take of Tapioca 2 tablespoonfuls, Water 1 pint. Boil it gently for an hour, or until it assumes a jelly-like appearance. Add sugar, wine, and nutmeg, with lemon- juice, to suit the taste of the patient and the nature of the case. 991. Carrageen , or Irish Moss Blanc-mange. Take of Carrageen half an ounce, Fresh milk . . . . .a pint and a half. DIETETIC PREPARATIONS. 319 Boil them down to such a consistence as to retain a form when cold ; remove any sediment by filtering, and then add the requisite quantity of sugar, with lemon-juice, or peach- water, to give an agreeable flavor. The moss, before being used, should be well washed in cold water, to remove its saline taste. 992. Iceland Moss Jelly. Take of Iceland Moss two parts,. Water . twenty parts. Boil down to six parts and strain. Then add; — Sugar four parts. Dissolve and set aside to cool. In consequence of its bitter principle, Iceland moss is more tonic than the other mosses. 993. Arroivroot. Take of Arrowroot . . . . • .1 tablespoonful, Cold Water sufficient, Boiling Water half a pint. Mix the Arrowroot with just sufficient cold water to soften the lumps, then pour on the boiling water, and stir con- tinually until the solution is gelatinous and transparent. Sweeten to the taste and grate in a little nutmeg. 994. Tons les Mois, or Carina Starch. This article is prepared like arrowroot. It is very delicate and valuable as a dietetic agent. When intended for infants, both this and the arrowroot are rendered more nutritious by the addition of fresh milk to the translucent jelly, made as directed above. In this case, how- ever, it is better to make the jelly more stiff by using a larger quantity of arrowroot, and then reducing it by milk to the proper consistence. 995.. Maizena, or Corn Starch. To one quart of boiling milk add gradually four tablespoon- fuls of the starch, previously rubbed into a paste with a little cold milk, add some salt and boil for five minutes, stirring briskly. Sweeten to the taste, and flavor with es- sence of vanilla, lemon, or orange. Then set aside to cool. 320 DIETETIC PREPARATIONS. 996. Boiled Flour. Take of Fine Flour a pound. Tie it up in a linen cloth as tight as possible, and after fre- quently dipping it in cold water, dredge the outside with flour till a crust is formed round it, which will prevent the water soaking into it while boiling. It is then boiled until it becomes a hard dry mass. Two or three tablespoonfuls of this may be grated and pre- pared in the same manner as arrowroot, for which it forms an excellent substitute. This is an admirable food for children, nutritious and wholesome. "When the bowels are constipated, the editor has found great advantage in substituting for the white flour bran meal, or unbolted flour of fine quality, treating it in the same way; and by the continuous or even occasional use of this, the bowels are kept regular, with even more nourishment afforded. In the constipation of tubercular children, this latter is espe- cially useful. [997. Meigs 1 Food for Infants.] "Is made by dissolving a small amount of prepared gelatine or Russian isinglass in water, to which is added milk, cream, and a little arrowroot or other farinaceous substance that may be preferred. The mode of preparation and the proportions are as follows : A scruple of gelatine (or a piece two inches square of the flat cake in which it is sold) is soaked for a short time in cold water, and then boiled in half a pint of water until it dissolves — about ten or fifteen minutes. To this is added, with constant stirring, and just at the termination of the boiling, the milk and arrowroot, the latter being previously mixed into a paste with a little cold water. After the addition of the milk and arrowroot, and just before the removal from the fire, the cream is poured in, and a moderate quantity of loaf-sugar added. The proportion of milk, cream, and arrowroot must depend upon the age and digestive power of the child; for a healthy infant within the month, I usually direct from three to four ounces of milk, half an ounce to an ounce of cream, and a teaspoonful of arrowroot to the half pint of water. For older children the quantity of milk and cream should be gradually increased to a half or two-thirds milk, and from one to two ounces of cream. I seldom increase the quan- tity of gelatine or arrowroot." Jxo. F. Meigs. DIETETIC PREPARATIONS. 321 998. Vegetable Soup. Take one turnip, one carrot, two potatoes, and one onion. Let them be sliced, and boiled in one quart of water for an hour. Add as much salt as is agreeable, flavor with a small portion of potherbs, and pour the whole upon a piece of dry toast. This preparation forms an agreeable substitute for animal food, and may be given when the latter is inadmissible. 999. Mutton Broth. Select two tender mutton chops, put them into a saucepan, add one quart of cold water and a little salt, cover the pan, aucl cook slowly for two hours. Then skim off all the fat, and add one tablespoonful of rice, one white potato, one turnip, and a little parsley chopped fine. Simmer for three- quarters of an hour, then pour into a bowl and remove the chops and all of the remaining fat. This broth is nutritious and palatable. 1000. Beef Tea. Take of Lean Beef, cut into shreds .... 1 pound, Water 1 quart. Boil for twenty minutes, taking off the scum as it rises. Strain the liquor, and add salt according to the taste. This preparation is more nourishing than ordinary broths, and very palatable. 1001. Liebigh Beef Tea, " One pound of lean beef, free of fat, and separated from the bones in the finely-chopped state in which it is used for mince-meat, is uniformly mixed with its own weight of cold water slowly heated to boiling, and the liquid, after boiling briskly for a minute or two, is strained through a towel, from the coagulated albumen and fibrin, now become hard and horny. Thus we obtain an equal weight of the most aromatic soup, of such strength as cannot be obtained even by boiling for hours from a piece of flesh." This is to be seasoned to taste. Dr. Beneke. 1002. Essence of Beef. Put a sufficient quantity of lean beef, sliced, into a porter bottle to fill up its body, cork it loosely and place it in a 21 822 DIETETIC PREPARATIONS. pot of cold water, attaching the neck to the handle of the vessel by means of a string. Boil for an hour and a half or two hours, then decant the liquor and skim it. To this preparation may be added spices, salt, wine, brandy, etc., according to the taste of the patient and nature of the disease. [1003. Marcefs New Process of Beef -tea.'] Take one pound of lean beef, cut into small pieces ; put into a pint of cold water. To this add — Hydrochloric Acid (sp. gr. 1.15) . . 58 grains, or about 50 minims, Boudault's Pepsine . . . .15 grains. Bring it up to about 100° Fahrenheit, and maintain it at that temperature in a water-bath until the meat becomes dis- integrated ; strain it then, and neutralize with 80 grains of bicarbonate of soda. This makes a palatable and exceedingly digestible nourish- ment. In cases of fever, where the acid is rather desirable than not, the editor has found it quite agreeable to the patient, without the addition of the sc [1004. Eggs, Cream, and Extract of Beef.] Wash two ounces of the best pearl sago, until the water poured from it is clear ; then stew it in a half pint of water until it is quite tender and very thick ; mix with it half a pint of good boiling cream and the yelk of four fresh eggs, and mingle the whole carefully with one quart of good beef-tea, which should be boiling. Let cool sufficiently, when it is ready for use. T. H. Tanner. The editor has used this elegant preparation among his patients when nothing else could be taken and retained. [1005. Preparation of Raw Beef] " Take of Fresh lean beef free from fat or bones Water Inodorous Glycerine . Pure Brandy Sulphate of Quinise . Oil of Ceylon Cinnamon Dilute Phosphoric Acid 3 lbs. avoirdup., 8 fluidounces, 6 fluidounces, 4 fluidounces, 8 grains, 4 drops, sufficient quantity. DIETETIC PREPARATION'S. 323 Cut the beef finely, chopping or dividing in a sausage-cutter, add the water and expose the mixture to the heat of a water- bath, with constant stirring, till it attains a temperature of about 145° F. ; transfer to a strong muslin drilling bag, and express the juice with powerful pressure; set this juice in a cool place until the floating fat solidifies, then skim care- fully. Take of this juice about half a fluidounce, and add to it in a mortar the sulphate of quinia, rub it up smooth, and add sufficient dilute phosphoric acid to make a clear solution; then return this solution to the remainder of the juice, and pour in the glycerine, brandy, and oil of cinna- mon previously mixed. " If force has been used in the expression of the juice, the finished preparation will measure about 32 flaidounces, vary- ing a little according to the juiciness of the beef. As thus prepared it is an agreeable article as respects appearance and taste, the raw flavor of the beef being effectually masked. It will keep perfectly sweet for two weeks, and probably longer." The above formula was furnished by my friend J. E. Carter, manufacturing chemist of this city, and I can say that I have used the preparation as a nutriment in advanced phthisis, when it was found acceptable to the stomach, and seemed to maintain vitality when it was at a very low ebb and all other food disgusted. It may be given in doses of a wineglassful after meals. 1006. Hartshorn Jelly. Take of Hartshorn Shavings . . . . .4 ounces, Water ....... 1 quart. Boil over a gentle fire until one pint of the water be dissipated. Strain, and add lemon-juice, sugar, and half a pint of wine. This forms, either with or without the last-named ingredi- ents, a very nourishing diet for convalescents; and, when mixed with an equal portion of milk, is well adapted to the bowel complaints of children. Isinglass may be used instead of the hartshorn shavings, if preferred. 1007. Calves 1 Feet Jelly. Take a set of four feet, break them in small pieces, add to them one gallon of water, and reduce by boiling to one quart. Strain, and when cold, skim the fat entirely off. Add to this the shells and white of six eggs, well beaten, a pint of wine, a pound of loaf sugar, and the juice of four 824 DIETETIC PKEPARATIONS. lemons, and let them be well mixed. Boil the whole for a few minutes, stirring constantly, and then pass the jelly through a flannel strainer. This forms a very nutritious article of diet for the sick and convalescent. 1008. Gelatine Jelly. Soak one ounce of gelatine for ten minutes in half a pint of cold water ; then add the same quantity of boiling water, and stir till the gelatine is dissolved, applying heat, if ne- cessary. Add half a pint of good wine, the peel and juice of two lemons, and sugar, according to the taste. Then add the shell and white of one egg, well beaten together ; boil the jelly for five minutes, and strain while hot through a piece of felt or flannel. Set aside in a cool place until the jelly becomes stiff. This is both palatable and nutritious. 1009. Blanc Mange. Boil one ounce of shred gelatine in a quart of milk for ten minutes, stirring constantly. Sweeten to the taste, flavor with peach- water, or essence of vanilla, and strain into a mould. 1010. Chicken Water. Take one half of a chicken divested of all fat, and break the bones ; add to this half a gallon of water, and boil for half an hour. Strain, and season with salt. This water is directed by some physicians in the early stages of cholera. Taken warm it promotes vomiting and washes out the stomach. 1011. Chicken Broth. Clean half of a chicken, and pour on it one quart of cold water; add a little salt, and one tablespoonful of rice. Cover the vessel closely, and boil for two hours. Throw in near the end of the boiling a little parsley, chopped fine. Skim the broth before using. This is one of the most valuable articles of diet at the com- mand of the physician in the low stages of disease, when the patient's system requires support, but his digestive powers will not admit of solid food. DIETETIC PREPAKATIONS. 32; 1012. Suet Ptisan. Take of Mutton Suet Milk Starch. Boil slowly for half an hour. This may be used warm as a common drink in dysentery. 2 ounces, 1 pint, half an ounce. 1 ounce, 1 drachm, 1 ounce, 3 pints. 1013. Mucilage of Starch, etc. Take of Starch Powdered Cinnamon Grum Arabic .... Boiling Water .... Boil until reduced one-third, and strain. The above may be taken for a common drink in dysentery. 1014. Mulled Wine. Take two drachms of bruised cinnamon, half a nutmeg, grated, ten bruised cloves, and half a pint of boiling water. Infuse one hour, strain, and add of hot port, or hot sherry wine (or of good domestic wine), one pint, and white sugar, one ounce. Mix. This is a mild stimulant drink, used in the convalescence from low forms of disease. Wine Whey, (See Formula No. 342.) Mustard Whey. (See Formula No. 341.) 1015. Rennet Whey. Take of New Milk . . . . .1 quart, Rennet .a large spoonful. Heat the milk and then add the rennet. Boil until the curd separates and is all taken off. To many persons this forms a very agreeable nutriment. 326 DIETETIC PREPARATIONS, [1016. Brandy Mixture.'] Take of Brandy . ... . . .4 fluidounces, .Cinnamon Water . ... 4 fluidounces, The yelks of two eggs, Sugar J ounce, Oil of Cinnamon . . .2 minims. Beat the eggs perfectly light, add the sugar and cinnamon water ; then the brandy with the oil of cinnamon in solu- tion ; beat the whole together. A delightful nutriment in prostration or low fevers. From one to three tablespoonfuls to be taken as required. P. Squire. 1017. Vinegar Whey. Take of Milk . . . . . . .1 pint, Yinegar half an ounce. Boil for a few minutes, and separate the curd. 101.8. Tartar Whey. Take of Milk ....... 1 quart, Cream of Tartar .... half an ounce. Boil until the curd separates. OF POISONS. Cases of poisoning are so sudden and so awful that no time is to be lost in administering relief. To do this with judg- ment and effect, it is requisite to be familiar with all the usual antidotes; and of these, we have accordingly selected some which possesses an acknowledged efficacy, omitting at the same time many others that are unworthy of confidence. For the purpose of convenience we have arranged the Poisons alphabetically, with the appropriate antidotes attached to each. But, as has been remarked when speaking of Emetics, our chief reliance in these cases is upon free vomiting, in- duced by those articles which are most speedy in their effect. Dr. Beck prefers sulphate of zinc, whenever it can be procured, and adds, "but if vomiting be present, we may aid it by dilu- ents or a vegetable emetic. Tartrate of antimony should never be given." Yet, even from this treatment, little can be ex- pected when the deleterious substance has remained long in the stomach ; and the stomach-tube and syringe will be indis- pensable. To protect the stomach and intestines from the direct ope- ration of poisons, it is generally recommended to give milk, lime-water, soap, or drinks sweetened with sugar or honey. Oils and other fatty substances are found to be injurious. When the vomiting has ceased, and retching and pain con- tinue, Mr. Hume advises the free administration of carbonate of magnesia with tincture of opium, suspended in water. A general antidote for poisoning, in which the nature of the poison is unknown, consists of equal parts of calcined magne- sia, pulverized charcoal, and hydrated peroxide of iron, which are to be diffused in water, and be given freely. Although these articles are simple and innocent in their operation on the system, they will probably prove efficient, as one or another of them is an antidote to most of the mineral poisons. The albumen of eggs and tannic acid are also general anti- dotes of great value. The former neutralizing corrosive sub- 328 of poisons. limate and other salts, and the latter precipitating all of the vegetable alkaloids as tannates. ALCOHOL. Large quantities of alcoholic liquors, taken by persons unaccustomed to their use, often produce fatal effects. The treatment in such cases is to evacuate the stomach as soon as possible ; but from the rapidity of absorption this may not always be effectual. The patient must be kept roused and cold affusion plentifully used. Large draughts of tea or coffee ought to be taken until the stomach is thoroughly evacuated. ALKALIES. Ammonia, 2^otassa, soda, and their carbonates, are seldom taken in poisonous quantities. When it so happens, the best antidote is common vinegar; it is always at hand, and its affinity for these substances is sufficiently strong to neutralize them. Also, a fixed oil, as olive oil, should be given in large quantity — several pounds being required where a large por- tion of the alkali has been taken; it acts partly by rendering the vomiting easy and free, and partly by converting the alkali into a soap. ANTIMONY. The preparation of this mineral, by which poisoning is most commonly produced, is tartar emetic. This of itself pro- duces violent vomiting, and therefore our first efforts should be directed to keeping up the emesis by means of mild diluents and mucilaginous preparations. Its antidotes are the alkalies, tannin, and astringent vegetable infusions, such as common tea, Peruvian bark, infusion of galls, etc. These decompose the antimonial salt. When the vomiting is excessive, opium by injection will assist in allaying it. AESENIC. Until the present century there was no known antidote to this deadly poison, and the sole dependence of the practitioner was upon mild diluents, albumen (such as the whites of eggs suspended in milk), or warm water and sugar. In the treat- ment of poisoning by arsenic, it is best first (if vomiting has of poisons. 329 been delayed) to give an emetic of mustard, or of the sulphate of zinc, and milk should be drunk liberally both before and after vomiting has begun. The patient should never be allowed to exhaust his strength in retching, without some milk or other fluid in his stomach to act on. The Cornish miners rely upon olive oil as an emollient to the stomach. The Hydrated Peroxide of Iron, freshly prepared, was announced in the year 1834, by Dr. Bunsen, of Grottingen, as an antidote for poisoning by arsenic; and its efficacy has been confirmed by MM. Orfila, Lesueur, Soubeiran, and Miguel, and also in this city by various chemists, and by experiments upon the inferior animals. The antidote is now officinal, and should always be kept on hand. The following direction will enable the most ignorant per- son to make use of this antidote until medical advice can be obtained. It must be administered as soon as possible after the discovery that arsenic has been taken, and as it causes no bad effect itself, should be given every five or ten minutes, UNTIL ENTIRE RELIEF IS OBTAINED. It is said that twelve parts of it are necessary to neutralize one of arsenic. The dose for a grown person is a tablespoonful ; for children a teaspoonful. The bottle to be well shaken before each dose. In cases of emergency, it may be prepared by simply precipitating the muriated tincture of iron, or a solution of the persulphate of iron, by ammonia, and washing the precipitate. Should the patient survive (and the probability is in his favor if the antidote be given early and faithfully), the inflam- matory symptoms must be combated on the general principles for treating inflammation. The diet should consist exclusively of milk, gruel, cream, rice, and similar bland articles for several days. In a case of poisoning in this city, where half an ounce of the powdered arsenic had been taken, and was followed by extreme thirst and vomiting, all the symptoms were allayed by freely taking the hydrated peroxide of iron. Only a slight gastritis followed, which was readily subdued. The hydrated oxide forms with the arsenious acid an inso- luble salt. In place of the hydrated oxide, the rust of iron and precipi- tated carbonate should be resorted to in cases of emergency, possessing as they do, to a certain extent, the power of anti- dotes. Magnesia, in the gelatinous or hydrated state, if given in large doses, acts also as an antidote, and in several cases lately reported was used with complete success. It can be 830 OF POISONS. rapidly prepared by precipitating a solution of Epsom salts by ammonia. When the poison has been taken in the form of Fowler's solution, Dr. Dunglison recommends copious draughts of lime- water to be used ; but this should not preclude the employ- ment of the hydrated oxide of iron. BARYTA. The carbonate of baryta and the chloride of barium are poisonous, and the latter has been taken by mistake for Glau- ber's salts. In cases of poisoning with either, the alkaline sulphates should be given freely, and resort be had to the stomach-pump and emetics. The true antidote is sulphate of magnesia or soda; with these a sulphate of baryta is formed, which is perfectly insoluble, and may be brought off by emetics and copious diluents, oleaginous or albuminous. COPPER. The sulphate (blue vitriol) and subacetate (verdigris) are the salts of this metal from which poisoning most frequently results; the latter often from the careless use of culinary vessels or mineral-water fountains. Vomiting should be encouraged by the free use of tepid water, milk, and mucilages. According to Orfila, albumen in the form of white of eggs is the best antidote, and sugar, formerly in much repute, acts only as an emollient. In the absence of eggs, milk or wheaten flour should be employed. Vinegar in all cases must be avoided. The French physicians have tried iron-filings, in consequence of the power possessed by this metal of reducing the salts of copper ; and the results they obtained, in some experiments performed on animals, are such as to justify con- siderable confidence in the antidote. The iron decomposes the cupreous salt, and precipitates the copper in a metallic and consequently in an inert state. GOLD. The nitro-muriate or terchloride of gold is a powerful poi- son. Its antidotes are sulphate of iron (which throws down the gold in a metallic state), and albuminous substances, fol- lowed by the free use of mucilaginous drinks. OF POISONS. 331 IODINE. Ten or twenty grains of iodine sometimes, though, not always, produce constriction of the fauces, nausea, vomiting, and severe colic pain. Larger doses endanger life. The best antidote for its preparations is starch freely given, or, what answers the same purpose, flour mixed with water. Magnesia is also recommended. Yomiting should be induced by mus- tard or some other prompt emetic. LAUDANUM. Laudanum, when taken in large quantity, must be with- drawn from the stomach by active emetics, such as mustard, sulphate of zinc, sulphate of copper, or alum, or by tickling the fauces. The stomach-tube should then be used to remove whatever remains of the laudanum in the stomach. This should be followed by a purgative, to carry off any of the poison that may have entered the bowels. The free use of vegetable astringents and strong coffee will also be serviceable. An important part of the after-treatment is the maintenance of artificial respiration, besides which active stimulants are often required. Iodine, bromine, and chlorine are stated by M. Donne, of Paris, to be antidotes for poisoning by nux vomica and opium. M. Ornla thinks that the decoction of galls may with propriety be used as an imperfect antidote, until the narcotic can be evacuated from the stomach. (See Opium.) LEAD. The acetate is the only preparation which is resorted to as a poison. The sulphate of magnesia or soda is its true anti- dote, as it converts the poison into a sulphate, which is inert. The alkaline carbonates and bicarbonates and the phosphate of soda are also good antidotes. If the patient does not vomit, give an emetic of the sulphate of zinc, which will not only empty the stomach, but convert any remaining soluble lead into an insoluble sulphate. Milk or albumen should also be given in large quantities, as it has been found that the albuminous principle of milk is a very effectual precipitant of the oxide of lead; a compound which, though not entirely inert, is far less active than the acetate, and tends to prevent the action of the poison as a corrosive on the stomach. 332 of poisons. MERCURY. All the preparations of this metal are poisonous, and corro- sive sublimate in particular. Our chief and only dependence, according to M. Orfila, is upon the albumen of eggs, copiously swallowed, or introduced through the stomach-tube, which should be resorted to when the patient cannot swallow or vomit. Enemata of the same should also be used. If the albumen be taken in sufficient quantities, it decom- poses the sublimate, forming a triple compound of albumen, muriatic acid, and calomel. If the remedy excites fresh vomit- ing, so much the better ; and if symptoms of gastritis appear, they are to be treated in the usual way. M. Orfila has also established that a fatal dose of corrosive sublimate may be swallowed by animals with impunity, provided the white of egg, or any other kind of fluid albumen, be introduced shortly before or after into the stomach. Cases are also upon record which establish that it possesses an equal efficacy in man. The gluten of wheat flour is also strongly recommended on the same principle, as an antidote to corrosive sublimate. To administer it, nothing more is requisite than to mix the flour with water. The quantity taken must be very con- siderable. It is said to reduce the sublimate to the state of calomel. Gluten of wheat flour is also given in the form of an emul- sion with soft soap, by mixing partly in a mortar and partly with the hand 5 or six parts of fresh gluten with 50 parts of soft soap. When neither albumen nor gluten is at hand, milk forms a good substitute. The only other antidotes deserving of mention here are a mixture of two parts of iron filings and one of zinc, meconic acid, and the hydrated proto-sulphuret of iron. The first was recommended by Dumas, and must obviously operate by bringing the mercury to the metallic state. The meconic acid, particularly when combined with an alkaline base, affords, with corrosive sublimate, an insoluble and inert permeconate of mercury. The meconates of the ordinary alkalies, however, can scarcely be obtained in sufficient quantity to be applied to such a purpose; and from the smallness of the saturating power of meconic acid, it would be hazardous to administer the quantity of opium which would be adequate to the decom- position of a few grains of corrosive sublimate, inasmuch as the muriate of morphia, which would be contemporaneously formed, is a narcotic medicine of very considerable energy. of poisons. 333 The hydrated proto-sulplmret of iron was proposed by Mialhe, and confirmed by Orfila, who says that if it be taken imme- diately after the ingestion of the poison, it completely destroys the poisonous quality of corrosive sublimate. MINEEAL ACIDS. The first, because the most ready method of counteracting the action of the mineral acids, is the copious use of water, warm or cold, milk, oil, or mucilage, which, by simply dilut- ing them, renders them less acrid, and at the same time assists the stomach in rejecting them. This course should be fol- lowed until the proper antidotes are prepared. These are the alkalies, alkaline earths and soaps, common pearlash or car- bonate of potassa, carbonate of magnesia, chalk, and soap in solution. Calcined magnesia, though advised by some authors, is objectionable, inasmuch as the rapidity with which it would combine with acid in the stomach, might alone produce in- flammation of that organ. The smallest quantity of nitric acid which is known to have destroyed life is two drachms ; the smallest fatal dose of muri- atic acid was one ounce. NAKCOTICS. The remedies employed in all cases of poisoning from this class of substances, are nearly the same, viz., the most active emetics, as sulphate of zinc, alum, and mustard in large doses. In all cases where it is possible, the stomach-tube should be employed. After these evacuations, tannic acid or strong decoctions of tea, coffee, or the vegetable astringents, with cold affusion, are proper. Electro-magnetism is also service- able, together with brandy, ammonia, and other powerful stimulants, and artificial respiration. There is no positive antidote to any of the vegetable alka- loids. Tannic acid combines with all of them, and forms salts which are insoluble in water, but are soluble in vinegar and the gastric juice. Hence, the administration of this acid is beneficial, time being gained for the removal of the poison in the form of a tannate from the stomach. If not removed, the tannate will be dissolved by the gastric fluids. After emesis, charcoal may be given freely, as it possesses the singular pro- perty of absorbing and retaining coloring matters, vegetable acids, and the alkaloids. 334 of poisons, NITEE (Nitrate of Potassa). This salt is sometimes taken in mistake for Epsom or Glau- ber's salts. When this happens, vomiting should be excited as speedily as possible, followed by the free use of mucilagi- nous drinks, hot gin-toddy, brandy and water, etc. As there is no antidote to this poison, in case these means should fail we must resort to the stomach-pump. OPIUM. We cannot do better in this place than transcribe what Dr. T. E. Beck, of Albany, says of the antidotes to opium. " The experiments of Orfila have demonstrated that the administration of vinegar, or rather vegetable acids, previous to the evacuation of the poison by vomiting, will accelerate and aggravate the action of the opium ; but that when the opium has previously been expelled, water acidulated with vinegar, or any other vegetable acid, will tend to diminish and correct the effects. Coffee, when prepared in strong de- coction or infusion, rapidly lessens the symptoms, but cannot be considered as an antidote. The result of his experiments led him to give the following directions for the treatment of a person poisoned by opium. Induce vomiting, if possible, with sulphate of zinc, or sulphate of copper ; but the adminis- tration of watery liquids with the view of promoting the vomiting, should be forbidden, as they dissolve the opium and promote its absorption. In order to insure the action of the emetic, the patient must be kept roused by discharging cold water over the head and breast ; yet cold affusion must be avoided in the advanced stage, when the body is cold, and the breathing scarcely perceptible. To insure success, in every case the patient must be kept awake, either by dragging him up and down between two men, or by flagella- tion on the back and soles of the feet. Artificial respiration may be used in desperate cases with propriety. Bleed the patient immediately after the rejection of the poison, and repeat this if necessary. Afterwards administer alternately water acidulated with any vegetable acid and a strong infu- sion of coffee 1 warmed, and in ten or twelve hours exhibit an enema, and let the arms and legs of the patient be well rubbed. Purgative clysters should be continued, if it be Dr. H. F. Campbell reports a case in which an injection of twenty grains of caffein in an infusion of coffee was attended with the happiest effect. of poisons. 335 suspected that any of the opium still remains in the large intestines." — Beck, Med. Jurisprudence, vol. ii. p. 403. These remarks are applicable to the poisonous effects induced by other articles of the Narcotic class, as belladonna, hyoscyanrus, stramonium, etc. Yet as these are not often taken with siiicidal intentions, the quantity is seldom inordi- nately large. Emetics, if given soon after the poison has been swallowed, will at least remove a part of it ; after which the practitioner must necessarily be governed in the treatment by the nature of the peculiar poison, the amount taken, and the patient's constitution. Stimulants are occasionally neces- sary from the first ; in other instances, depletion ; but more frequently, each is in turn called for. As belladonna and opium manifest a different, and in some respects an opposite effect upon the brain, they have been recommended as antidotes to each other in cases of poisoning. This recommendation, however, should not interfere with the measures above described. It may be received as an adjuvant, but not as a substitute for the usual plan of treatment. OXALIC ACID. Death from this poison is generally sudden. Lime-water, or a mixture of chalk and water, is recommended by Dr. Thompson, for the purpose of converting the acid into oxalate of lime. The carbonate of magnesia, also, has been found by experiment to counteract the poison ; but the alkalies must be avoided, as they act with an energy little inferior to the acid itself. It is advisable to avoid giving warm water with a view to accelerate vomiting ; for dilution promotes the absorption of the poison. PHOSPHOKUS. This substance acts so immediately and so powerfully in decomposing the animal tissues, that no available antidote has hitherto been suggested. A small portion is sufficient to destroy life. Nevertheless, large quantities of mild demul- cent liquids should be exhibited to shield the alimentary canal, and magnesia to neutralize the phosphorous and phos- phoric acids which may be formed. PKUSSIC ACID. This deadly poison, in its purity, acts with such rapidity as to leave no time for the administration of antidotes. When 336 of poisons. taken in small quantities, much diluted, its action is less rapid, producing symptoms of excessive prostration, convulsions, and coma. Cold affusion to the head has been found very- effectual in such cases, and when applied before the convul- sive stage has passed, has often succeeded. The head should be kept elevated, and the water poured from a height upon the occiput and spine. The inhalation of ammonia is the antidote most to be relied on, many experiments having proved its efficacy. It should not be used of too great strength, which would endanger inflammation of the air- passages and stomach ; the strong aqua ammonia, diluted with twelve parts of water, is recommended by Orfila. Chlorine also possesses strong claims as an antidote, and, from the results of his experiments, is believed by Orfila to be the best which has yet been proposed. In all cases, artificial respiration should be kept up while there is a hope of sustaining or restoring life. Ether and chloroform have been recommended, and no doubt will eventually prove of great value from the rapidity with which they act. Cases of poisoning with the oil of bitter almonds, cherry- laurel water, and other substances containing prussic acid, are not unfrequent, particularly among children. After evacu- ating the stomach, these require the same treatment as for prussic acid. Poisoning by cyanide of potassium may be best treated, according to Dr. Alfred S. Taylor, by a strong solution of sulphate of iron. SILVEK. The nitrate of this metal is sometimes taken by mistake; its antidote is comon salt, largely given, with copious draughts of mucilaginous drinks to promote vomiting. The salt pro- duces an insoluble chloride, which has no power on the system. TIN. When any of the salts of tin are taken, albumen of eggs, flour, or milk, given freely, is the appropriate remedy. Milk forms a coagulum with the chloride of tin (Dyer's spirit), and renders it innoxious. Lime-water or the alkalies would de- compose this salt, and thus render it inert. of poisons. 337 VEGETABLE POISONS. See "Narcotics" and "Opium." ZINC. The sulphate of this metal is occasionally taken in an over- dose. Warm water and emollient drinks are proper in such cases; but milk is particularly useful, from its power of de- composing the sulphate; also albumen, magnesia, etc. Vege- table astringents may be beneficially used. The crystallized sulphate of zinc very closely resembles the sulphate of magnesia, and has been mistaken for it — a fact to be borne in mind by apothecaries and physicians. 22 APPENDIX I. ON THE ENDERMIC USE OF MEDICINES. " The science of medicine," says Dr. Gerhard, 1 "has recently received an important auxiliary to its resources, by the dis- covery that remedial substances, when applied to the cutis, after the removal of the epidermis, produce their peculiar effects with nearly the same energy as if introduced into the alimentary canal. This mode of exhibition, which has re- ceived the name of the endermic method or endermic medication, is always found much more efficacious than the iatroleptic method of Christien, or the administration of medicines by means of frictions on the cuticle." The endermic method requires the previous separation of the cuticle, which is best effected by a blister about four inches square. The cuticle should then be punctured or removed in very small patches, so that the medicine may come in contact with the vesicated surface. Substances used in this way must be applied in two or three times the quantity requisite when given by the mouth. "The remains of the substance applied are much less than the original quantity, and sometimes no trace of it can be perceived; the whole appearing to be ab- sorbed or mingled with the secretions." We avail ourselves of Dr. Gerhard's valuable paper for the following facts in relation to those medicines which act most effectually in the endermic method. Sulphate of Quinia. — A blister to be applied to the epi- gastrium during the apyrexia; and if the paroxysm returns before the quinia can be used, defer it until the next apyrexia. Apply four grains of powdered sulphate of quinia (either alone or with an equal quantity of starch), four times a day, for two successive days. A less irritating plan, however, is 1 North Amer. Med. and Surg. Journ., April, 1830. 340 OX THE USE OF ETHER AND CHLOROFORM. to dissolve sixteen grains of the sulphate in two ounces of water, with which the blistered surface is to be repeatedly wet during the day by means of a soft linen cloth. There is no occasion to remove the loose epidermis ; it is all-sufficient to puncture it in several places to allow the solution to touch the denuded surface. Morphia. — The acetate and sulphate act readily and effectu- ally ; the latter is preferable, because more soluble and less irritating. It may be applied in powder, in solution, or in the form of cerate. The close varies from half a grain to two grains, and its effects are speedily perceptible. Digitalis. — Dose, two grains three times a day. Aloes. — This medicine acts on the bowels with nearly the same certainty as if taken internally. Dose, ten grains, to be repeated, if necessary, in a few hours. Gamboge, owing to its solubility, purges freely in the en- dermic method. Dose, from five to eight grains. Rhubarb, jalap, elaterium, and croton oil, contrary to what might be expected, do not produce catharsis, although they excite severe local irritation. Squills. — This medicine in powder, sprinkled on a blistered surface three times a day, in the quantity of four grains at each application, causes copious diuresis. Its power is in- creased by combination with digitalis, in the proportion of four grains of the former to one of the latter. Emetics from the vegetable kingdom all produce their effect in the endermic method ; and tobacco does so without any previous irritation of the skin. The same remark is appli- cable to mercury and iodine, which last is best applied in the form of ointment, made by rubbing a drachm with an ounce of cerate. Emetics derived from the mineral kingdom exert no specific action. B. E. II. ON THE USE OE ETHER AND CHLOROFORM. The employment of anaesthetic agents has now become so general, and their great value so fully attested by many emi- nent physicians and surgeons in all parts of the world, that we shall here give a brief account of their uses and mode of application. Indeed, the discovery of a means by which to give com- plete insensibility to pain during the performance of tedious ON THE USE OF ETHER AND CHLOROFORM. 341 surgical and dental operations, as well as to mitigate the spontaneous sufferings attendant on many diseases, must be considered one of the most important in the annals of medi- cine. That pain is useful in indicating the seat and progress of disease, cannot be denied; yet, on the other hand, its severity may exhaust life, and to allay it is often the most difficult and necessary part the physician is called upon to perform. The inhalation of ethereal substances now gives the practitioner more or less control over these "ills that flesh is heir to," enabling him to alleviate some, and wholly to prevent others. Notwithstanding the benefit to be derived from its judi- cious use, the mode of inhalation is also capable of producing much evil in the hands of the unskilful and ignorant ; and it should, therefore, be employed by those only who are ac- quainted with its diversified operation. Ether and chloroform produce essentially the same effects, but the latter is much the more powerful and rapid in its action. The progressive stages of etherization seem to be pretty much as stated by Mr. Sibson, viz : — 1. Cerebral excitement. 2. Cerebral derangement, staggering intoxication. 3. Cerebral sleep (sopor); pupils contracted ; dreams ; reflex functions of the brain and spinal marrow still active. 4. Cerebral death (coma); reflex functions of the medulla and spinal marrow still active. 5. Death of spinal marrow ; cessation of respiration (heart's action generally still present). 6. Cessation of heart's action. He also says: "It is very important to be able to tell easily when the stage of safety — sopor, is about to merge into that of danger — coma. The action of the pupils is the key to this knowledge. Inhalation should not be continued one instant after the pupils, previously contracted, have begun to dilate. "If unconsciousness can be secured by sopor, the inhala- tion should not be carried on to produce coma. If complete muscular relaxation be sought for, as in hernia, to facilitate taxis ; in dislocation, to make reduction easy ; and in tetanus, then it will be needful, in general, to urge the patient from sopor into coma ; but as soon as the muscular relaxation is secured, the inhalation should cease. When chloroform or ether is employed in chorea, delirium tremens, or other affec- tions, it should never be urged beyond sopor. In neuralgia, 342 ON THE USE OF ETHER AND CHLOROFORM. it is not usually needful to produce unconsciousness. When- ever the pain disappears, the inhalation ought to cease." According to Dr. Snow, a necessary precaution for watch- ing the effects of ether and chloroform is, that they possess an accumulative property ; their influence sometimes increas- ing for twenty seconds after the inhalation is discontinued. It is seldom necessary to carry the process farther than the production of sopor ; in this dreamy state insensibility to pain is perfect, and in some persons much earlier. Many patients seem to be perfectly awake to all mental impressions, and even take an interest in the progress of the operation, without feeling the slightest pain, and, indeed, in some in- stances, experiencing agreeable sensations. The influence of these agents being transmitted by the blood, pervades the whole system simultaneously, and par- ticularly excites the capillary circulation, as evinced by the injected conjunctiva, increased lachrymal and salivary secre- tions, and turgidity of the face and neck, the redness of which, however, soon gives place to pallor. Although used heretofore only to produce general effects, it has lately been discovered by Mr. T. Nunneley, of Leeds, that local anaesthesia may be caused by these agents; and that the brain and other parts of the body not subjected to their influence remain unaffected. After an extensive series of experiments on different animals, he finds that, by immer- sion in a small quantity of the fluid, or by applying the vapor locally for a limited period, a limb may be rendered perfectly motionless and senseless, and, what may be an additional advantage, fixed in any desired position. The benefits likely to be derived from this new and valuable discovery promise to be very great. As regards the mode of applying these vapors, the princi- pal thing to be observed is, that they be freely diluted with atmospheric air. Many instruments for inhalation have been invented, but most of them have given place to a simple sponge ; and in the case of chloroform, a towel or handker- chief is perhaps as good as anything yet proposed. The degree of etherization does not depend so much upon the amount respired, as upon the peculiar constitution of the individual, and the physician is thus better able to regulate the amount, and judge of its effect. A drachm of chloroform, or even half a drachm, poured upon a handkerchief, and gradually brought close to the mouth and nose, will, in about two minutes, more or less, produce the required effect. Of ether, half an ounce may be poured upon a sponge, and more ON THE USE OF ETHER AND CHLOROFORM. 343 added from time to time if required. The full effect of ether is not generally obtained in less than four or five minutes. As regards their comparative merits, it may be said of chloro- form that it is less pungent, and requiring a less amount is more easily inhaled; but it is also said to have a greater tendency to produce involuntary muscular contraction, and exerts a more direct and powerful action on the heart than ether. As far as present experience goes, ether has been found the milder and safer of the two; and in the case of children, from their greater susceptibility, should always be given in preference to chloroform; etherization, in them, occurring in about two minutes. . According to Dr. Snow, the immunity from pain does not correspond exactly with the degree of narcotism, but is greater as the patient is recovering from the effects of the vapor than in the corresponding degree as he is getting under its influ- ence ; this is more particularly the case with ether, which he considers to possess superior anaesthetic effects to chloroform in proportion to the narcotism produced. When ether is in- haled, the patient sometimes completely recovers his mental faculties, although insensibility to the operation still con- tinues. The use of ether or chloroform is contra-indicated by the existence of any disease of the heart, tendency to engorge- ment of the lungs, or aneurism of any of the great vessels ; nor should it ever be used either during the existence of shock resulting from a severe injury. The existence of extreme debility is not always a contra- indication ; for, acting as a stimulant, the inhaled vapor seems to possess a sustaining power, and has been successfully used in a state of great collapse, as well as for its sedative influ- ence in low cases of typhus fever. Perhaps one of the most important uses of ether and chlo- roform is that for the relief of stricture, and to render easy the introduction of the catheter; here, in old and sensitive cases, as well as in retention of urine and the passage of cal- culi, they are invaluable. The physician, in using these vapors, should bear in mind that he is administering an agent of great power, of which he must carefully observe the effect; for the life of the patient is in his hands. In some constitutions, six or seven inspira- tions of chloroform have produced complete insensibility, and we should always be on our guard lest alarming symptoms suddenly supervene. These are marked by suspended respira- tion, livid skin, widely dilated pupils, the" eyes fixed, and the 344 ON THE USE OF ETHEK AND CHLOROFORM. iris immovable. The patient should be immediately laid upon the floor, cold water dashed upon the face, and the vapor of ammoDia applied to the nostrils. These will generally restore animation; if, however, respiration has entirely ceased, it will be necessary to bring it about by artificial means. The ab- straction of a few ounces of blood from the arm, or from the jugular vein, will also assist the renewal of the heart's action, by relieving distension. We should be careful, also, not to endeavor to make the patient swallow anything while in this state of insensibility, as cough might induce suffocation and hasten death. Besides sulphuric ether and chloroform, various other pre- parations have been found to possess anaesthetic properties.; as Aldehyde, Benzoin, Acetic Ether, Bisulphuret of Carbon, etc., but sufficient experiments have not yet been made to determine their relative value. As the action of chloroform depends upon its comparative purity, this may be tested by dropping it into the following mixture, viz : Sulphuric acid at 66° and distilled water, equal parts. When cool, this mixture will have a density by the areometer of 40°. (Sp. gr. 1.38.) Pure chloroform dropped into this liquid will fall to the bottom. 1 S. Gr. Morton. Dr. B. Q. Eichardson, of London, has recently brought to the notice of the profession a new anaesthetic, which he very highly extols as having all the good effect of chloroform, with greater safety and less disagreeable impressions subse- quently; this is the Bichloride of Methylene, or, as it has been named by Spencer Wells, "Chloromethyl." Dr. R. says of it that, having tried it upon the lower animals, and very fully upon himself, he has arrived at the following conclu- sions, viz., that it is more rapid than chloroform in its effects, produces less prolonged second degree of narcotism, complete narcotism prolonged and easily reproduced, and the recovery from its effects very rapid; its power of destroying life in the lower animals much below that of chloroform. It is soluble in ether and chloroform in all proportions. In the administration of anaesthetics, two very important points may be gained by proper attention to the method of its exhibition, viz., rapidity of action and economy of ma- terial. The former will be best insured by having a large evaporating surface, without much bulk of absorbing tissue, 1 French Journal of Pharmacy, 1848. ON THE USE OF ETHEK AND CHLOROFORM. 345 upon which, the liquid is poured for evaporation; the latter, bv having the absorbing tissue completely covered by some impervious material, to prevent external evaporation. Both these ends may be very happily attained by a method which the editor has been in the habit of using for some time in his practice, as follows: Take a large India-rubber ball, such as are sold in the shops for foot-balls, say about six inches in diameter, and cut in it an opening large enough to receive the face from the chin to the bridge of the nose, shaping it so that when adapted to the face it will fit closely, there being a notch at the upper portion in which the upper part of the nose will rest, leaving the eyes clear of any contact with the inhaler; then take one or two thicknesses of patent lint, according to the quality or weight of it, and line the whole internal surface of the ball, within about an inch of the mar- gin, fastening it by linen thread or silver sutures 'partially carried through the walls of the ball; the ridges of gum which are found upon the inside of these balls afford a good attachment for the lint. It is then ready for use, giving a portable inhaler which can be rolled up and put in the pocket, having a large evaporating surface, easily kept in position over the face without bringing the anaesthetic in contact with the skin (a point of no small importance in an irritable cuticle), allowing no more mixture of atmospheric air than you wish, no external evaporation ; and giving great rapidity of action, with no waste of fluid. I have produced complete anaesthesia with a fluidrachm of a mixture of one to two of chloroform and ether, and believe half an ounce of pure ether will have the same effect in a very much shorter' time than the old method of administration. A. H. S. GENERAL INDEX. PAGE ABSORBENTS . . .220 Alcohol, as a poison . . 328 Alkalies, as poisons . . . 328 Alteratives . . . .192 Antacids 220 Antemetics .... 38 Anthelmintics .... 120 Anti-intermittents . . .164 Antilithics .... 72 Antimony, as a poison . . 328 Antispasmodics . . . .156 Arsenic, as a poison . . . 328 Astringents . . . .196 Atomized fluids . . . .111 BATHS 302 Baryta, as a poison . . 330 Beverages for the sick . .313 Blisters 235 CATAPLASMS . . . 300 Cathartics . . . .42 Caustics 227 Chloroform, as an anesthetic . 340 Collyria 248 Copper, as a poison . . . 330 DIAPHORETICS . . . 77 Dietetic preparations . . 313 Diuretics ..... 60 Disinfectants .... 307 EMETICS . . . .33 Emmenagogues . . .113 Eudermic use of medicines . 339 Enemata . . . 57, 127 Epispastics .... 235 PAGE Escharotics . 227 Ether, as an anesthetic . 340 Expectorants . 89 External applications . . 227, 248 FOMENTATIONS . Jl Formulary proper . 1 . 304 53-326 Fumigations . 305 GARGLES IX Gold, as a poison . 267 . 330 TNHALATION . X Injections, for the rectum 5 106 7,127 for the ear 256 for the nostrils 258 for the urethra . 259 for the vagina . 264 subcutaneous . 265 Inoculation of medicines 265 Iodine, as a poison 331 Issues .... 233 T AUDANUM, as a poison . Jj Lead, as a poison . 331 331 Liniments .... 273 Lithoutriptics 72 Lotions .... 273 1/TINERAL acids, as poisons 111 Medicated pessaries ooo 265 Mercury, as a poison . So2 Mouth washes . . 267 VTARCOTICS . aS as poisons . 138 333 3-18 GENERAL INDEX. PAGE PAGE Nitrate of potassa, as a poison 334 OETONS . . . . .233 U Sialagogues . . . - . 160 Nitrate of silver, as a poison 336 Stimulants . . . .128 Suppositories . . . 59, 149 AINTMENTS . \J Opium, as a poison 285 Syrups ..... 93 334 Oxalic acid, as a poison 335 ^TARTAR EMETIC, as a poison 309 1 Tin, as a poison . . . 336 PESSARIES, medicated . A. Phosphorus, as a poison 265 Tonics . . . . .164 335 Poisons and their treatment 327 Poultices .... 300 TTAGINAL injections . . 264 T Vegetable poisons . . 337 Prussic acid, as a poison 335 pUBEFACIENTS . 239 yiNC, sulphate of, as a poison . 337 INDEX OF THE FORMULARY PROPER. The figures indicate the number of the Formula. ACETIC acid and ammonia gargle, 802 and camphor liniment, 840 Acetate of ammonia and antimonial wine, 160 and camphor water, 732 and assafcetida, 227 and aconite, 170 and opium, 733 and spirits of nitre, 161 of potassa and ammonia, 124 and buchu, 125 and digitalis, etc., 116 Aconite and acetate of ammonia, 170 and.carron oil, etc., 817 and colchicum, 169 and Dover's powder, 361 and veratrum viride, 171 Acorns, infusion, 506 Actual cautery, 650 Alcohol and vinegar collyrium, 716 Alkaline baths, 959 Almond and ipecac, 212 Aloes, canella, and serpentaria, 260 and canella, 281 enema of, 309 iron, and cloves, 269 and castor, 280 ignatia, and opium, 472 and gentian, pill, 55 jalap, and iron, 266 and blue pill, 39 alkaline mixture of, 82 and pepsin, 490 podophyllin, and iron, 478 guaiac, and rhubarb, 56 quinia, and blue pill, 537 zedoary, gentian, etc., 516 Aloin and podophyllin pill, 43 Alum, burnt, 658 and calomel ointment, 902 and catechu pessary, 786 Alum — catechu, and opium, 596 collyrium, 712 compound powder of, 585 curd, collyrium, 718 douche, 757 gargle, 795 and oak bark gargle, 789 and opium, 589 powder of, 4 and pomegranate gargle, 796 sage, and honey gargle, 812 and sulphate of zinc mixture, 11 whey, 624 Amber, camphor, and carbonate of am- monia, 839 Amber oil and cloves liniment, 847 and croton oil liniment, 700 liniment of, 843 and tolu, 215 Ammonia and assafcetida, 331 cantharides, and gentian, 276 carbonate of, 317 and quinia, 438 effervescing mixture of, 318 and ginger, 320 glycerin, etc., 857 muriate of, injection, 764 mixture, 572 caustic, 669 phosphate of, 573. and salt of tartar, 641 and tartar emetic liniment, 842 and valerian, 319 magnesia, etc., 645 Ammoniac, castor, etc., 240 conium, and squill, 188 and squill, 210 and nitric acid, 232 squill, and calomel, 189 and paregoric, 220 350 INDEX OF THE FORMULARY PROPER. Ammoniac — tolu, and senega, 209 Atnmonio-sulphate of copper, 745 Ammoniated guaiac and copaiba, 279 soap liniment, 702 Ammonium, bromide of, 220 Anaesthetic pill, 357 Angustura decoction, 503 Anodyne fomentation, 964 plaster, 400 Anthelmintic clyster, 311 Anti-gout pill, 44 Anti-herpetic ointment, 897 Antiseptic poultice, 950 Anti-psoric lotion, 849 Antimony and calomel, 175 and colocynth pills, 47 Dover's powder, and calomel, 187 Antimonial powder, James', 149 Tyson's, 148 wine and spirit of nitre, 163 and tolu, 167 and acetate of ammonia, 160 spirit of nitre and laudanum, 164 Antidyspeptic pills, Chapman's, 54 Aperient pill, Mitchell's, 49 Apple water, 975 Arnica mixture, 336 Aromatic powder, and oxide of silver, 586 syrup of galls, 626 wine, 870 Arrowroot, 993 Arsenic, caustic ointment of, 665 and iron, 522, 528 iodide of, and conium, 542 ' and iodine, 566, 569 morphia, and cascarilla, 568 nux vomica, and iron, 491 and opium, 443 and perchloride of iron, 571 Arsenical inhalation, 254 powder, caustic, 667 paste for dentists, 6G6 Arsenious acid and pepper, 541 Arsenite of potassa and opium, 459 Arseniate of soda, 570 Asclepias, infusion of, 173 Asiatic pills, 541 Assafoetida and acetate of ammonia, 227 and ammonia, 331 camphor, etc., 360 and castor, 413 enema, 418 magnesia, and laudanum, 381 mixture, 223 and soap pills, 407 syrup of, 199, 200 Assafoetida — valerian, and castor, 415 Atomized fluids for inhalation, 259 Atropia and tannin collyrium, 726 solution, 392, 393, 399 and nitrate of silver collyrium, 740 Ayer's cherry pectoral, 216 BALSAM of Peru mixture, 229 Barium, chloride of, and iron, 179 Barley water, 971 Bates' alum water, 744 camphorated water, 731 Baume de vie, 516 Becquerel's anti-gout pill, 45 Beeberine, sulphate of, 446 Beef tea, 1000 Liebig's, 1001 Marcet's, 1003 Beef, preparation of raw, 1005 Belladonna and bitter almond liniment, 403 solution, 373 cannabis, etc., 356 mixture, external use, 391 ointment, 901 and tolu, 234 lobelia, and squill, 222 Benzoic acid and juniper, 119 acid mixture, 120 and lead ointment, 916 Benzoated lard, 871 Benzinated lard, 871 Bestucheffe's tincture and valerian, 529 Bibron's antidote, 563 Bismuth and creasote mixture, 25 and cubebs, 340 and calomel pills, 15 elixir of, 519 and iron, 467 lotion, 865 and magnesia, 590 mixture of, 520 opium, and calomel, 591 powders, 466, 592, 593 and strychnia, 492 and strychnia pills, 17 Bitter almond solution, 384 Blackberry syrup, aromatic, 612 Black wash, 830 draught, 78 Blanc mange, 1009 Blake's toothache solution, 794 Blistering ointment, 676 Blistering plaster, 675 Blister tissue, 672 Bloodroot and wild cherry, 216 and naphtha, 224 INDEX OF THE FORMULARY PROPER. 351 Blue mass, 426 squill, and digitalis, 104 and taraxacum, 101 jalap, and aloes, 39 rhubarb, and soda, 40 Boiled flour food, 996 Boneset, infusion of, 172 Borax and glycerin, 856 and honey wash, 792 and opium collyrium, 722 and morphia lotion, 868 and myrrh gargle, 791 savin, and ginger, 264 Bran tea, 978 and flaxseed poultice, 943 Brandy and chloroform, 20 gargle, 788 mixture, 1016 Bread and milk poultice, 942 Bretonneau's iron pill, 477 British oil, 844 Bromide of ammonium, 220 of potassium ointment, 906 of potassium, 564, 565 and iodide of potassium, 567 Bromine and bromide of potassium, 565 solution, 562 Buchu and acetate of potassa, 125 and uva ursi, 126 and iodide of potassium, 180 Burdock decoction, 176 Butternut and jalap pills-, 46 CADMIUM, sulphate of, 753 sulphate, collyrium, 720 Cajeput and valerian, 322 and camphor, 742 Calabar bean, 394 Calomel, opium, and quinia, 536 opium, and nitre, 183 and opium collyrium, 710 opium, and ipecac, 152 opium, ipecac, and nitre, 151 bismuth, and opium, 591 and sulphuret of antimony, 153 and gamboge, 286 Venice turpentine, etc., 296 and conium, 358 camphor, and opium, 425 and pinkroot, 287 jalap, and rhubarb, 29 and carbonate of soda, 154 powders, 419 and oxgall, 545 squill, and tartar emetic, 190 and jalap powder, 26 and ipecacuanhae, 7 and rhubarb powder, 27 Calomel — and bismuth pills, 15 and colocynth pills, 41 and squill, 97 squill, and ammoniac, 189 and morphia powder, 16 nitre, and tartar emetic, 150 acetate of lead, and ipecac, 588 and sugar of lead, 587, 594 and soda powder, 28 powders, 535 antimony, and Dover's powder, 187 digitalis, and opium, 99 and verdigris powder, 937 and antimony, 175 injection, 773 and alum ointment, 902 and Goulard's cerate, 908 and sulphate of zinc ointment, 903 and tar ointment, 923 Calcined magnesia, 31 Calves' feet jelly, 1007 Camphor and opium collyrium, 728 and opium, 354 Dover's powder and nitre, 147 mixture, 274, 324 mixture, Parrish's, 605 mixture, Hope's, 606 and myrrh, 326 water and acetate of ammonia, 732 and ether, 328 julep of, 325 and musk, 409 carbonate of ammonia and amber, 839 and chloroform liniment, 404 assafcetida, etc., 360 and Hoffman's anodyne, 368 and olive oil enema, 310 and cantharides liniment, 838 and origanum liniment, 855 cantharides, and opium, 312 and poppies, 736 and chloroform, 327 and cajeput oil, 742 and lead, 821, 822 and opium plaster, 401 camphorated oil, 836 and acetic acid liniment, 840 and petroleum liniment, 854 and glycerine liniment, 859 and mercurial ointment, 688, 894 Camplin's diabetic bread, 988 Canella and aloes, 281 aloes, and scrpentaria, 260 Canna starch, 994 Cannabis, belladonna, etc., 356 352 INDEX OF THE FORMULARY PROPER. Cannabis — tincture, 383 Canquoin's caustic paste, 660 Cantharides and camphor, 838 camphor, and opium, 312 and spirits of nitre, 117 myrrh, and hellebore, 277 and savin, 262 ammonia, and gentian, 276 extract of, 681 liniment, 697 compound liniment, 698 Cantharidal collodion, 680 ether, 679 Cantharidine, 678 and castor oil, 860 Capsicum, iron, etc., 479 concentrated tincture, 695 and gentian, 314 and salt, 338 gargle, 806 Carbolic acid and carron oil, 816 and castor oil ointment, 925 and cubebs inhalation, 258 and mercury ointment, 911 Carbonate of ammonia ointment, 920 Carminative for infants, 382 Carrageen blanc manage, 991 Carron oil, 817 aconite, etc., 815 and carbolic acid, 816 Cascarilla, morphia, and arsenic, 568 sage, and boneset, 493 Castanello's powders, 986 Castor, ammoniac, etc., 240 and assafoetida, 413 iron, and aloes, 280 and succinic acid, 408 valerian, and assafoetida, 415 Castor oil mixture, 62, 63 and turpentine mixture, 65 molasses, and salt enema, 85 and quinia hair-wash, 861 and carbolic acid ointment, 925 and cantharidine lotion, 860 Cathartic pills, Griffitts's, 38 Catechu, 750 and alum pessary, 786 alum, and opium, 596 and laudanum, 615 and logwood, 611 Caustic collodion, 661 of Filhos, 656 potassa, 652 Cerium, oxalate of, pills, 18 iron, and nux vomica, 19 Chalk mixture, 607 compound, 639 and opium, 632 Chamomile and orange-peel, 499 Chapman's anti-dyspeptic pill, 54 peristaltic persuaders, 53 Charcoal, magnesia, and ginger, 637 and creasote ointment, 924 poultice, 946 Chaussier's liquor anti-syphilitique, 428 Chenopodium mixture, 303, 304 and rhubarb, 302 Chicken broth, 1011 water, 1010 Chinoidine, 439 Chloride of zinc lotion, 823 Chlorate of potassa and pomegranate gargle, 797 injection, 771 Chlorine inhalation, 257 fumigation, 970 injection, 783 liniment, 832 Chloric ether mixture, 374 Chlorinated lime mixture, 337 Chlorodyne, 376, 377 Chloroform and aconite liniment, 406 emulsion, 380 and camphor, 327 and soda, 23 and brandy, 20 and sulphate of soda, 621 and cardamom, 379 mixture, 375, 378 ointment, 915 and soap liniment, 405 and cyanide of potassium ointment, 900 liniment, compound, 853 Cholera mixture, 608 Jackson's, 609 Chromic acid, 670 Cider mixture, 112 Cimicifuga, 417 Cinchona mixture, 448 decoction, 447 elixir of, 517 cloves and cream of tartar, 432 and citrate of potassa, 457 bark, 431 uva ursi, and opium, 133 valerian, etc., 515 ferrated elixir of, 518 and valerian, 505 and iron, 488 serpentaria and soda, 433 and sulphate of copper, 444 and cardamom, 458 and muriatic acid gargle, 799 Cinchonia and iron, 456 sulphate of, 440 Cinnabar and serpentaria, 174 INDEX OF THE FORMULARY PROPER. 353 Citrate— of magnesia solution, 75 of potassa and cinchona, 457 solution, 158 Citrine ointment and tar, 909 Cloves and amber liniment, 817 iron and aloes, 269 Clove plaster, 687 Coal-tar ointment, 910 Cochineal and common salt, 289 mixture, 221 Cod-liver oil, 574, 575, 576 and iodine, 578 and quinia, 577 Colchicum and aconite, 169 and cream of tartar, 96 and digitalis, 122 digitalis and colocynth pill, 48 and quinia pill, 45 and elaterium, 121 Epsom salt and magnesia, 72 and laudanum, 83 and magnesia mixture, 71 morphia and colocynth pill, 44 Collodion of iodine, 877 Colocynth and antimony pills, 47 and croton-oil pills, 52 digitalis and colchicum pill, 48 and calomel pills, 41 morphia and colchicum pill, 44 and opium, 353 and podophyllin pill, 42 Columbo and ginger, 494 ginger, and iron, 462 and magnesia, 636 and phosphoric acid, 143 rhubarb, etc., 495 salt of tartar, etc., 646 Compound anodyne pill, 356 Conium and calomel, 358 and iodide of arsenic, 542 and Dover's powder, 185 squill, and ammoniac, 188 and lactucarium, 350 paregoric and tolu, 211 and iodine inhalation, 249 suppository, 390 Conia collyrium, 738 Conradi's collyrium, 730 Copaiba and ammoniated tincture guaiac, 279 and bicarbonate of soda, 137 compound mixture of, 130 cubebs, etc., 128, 129 and cubeb pills, 100 and tolu, 228 mixture, 127 compound mixture of, 131 injection, 777 23 of Copper, ammoniated, 778 pills of, 470 sulphate of, wash, 811 injection, 774 collyrium, 721 lead, and copal ointment, 932 Copal, lead, and copper ointment, 932 Cornmeal gruel, 983 Corrosive sublimate, 420 and conium, 422 Cowhage, electuary of, 301 ointment, 707 Cream, eggs, and beef, 1004 Cream of tartar and juniper berries, 106 and colchicum, 96 and sulphur, powdered, 34 and jalap powder, 32 tartar emetic and squill, 95 and lenitive electuary, 59 nitre and tartar emetic, 92 Creasote and charcoal ointment, 924 pills of, 315 and opium, 598, 599 and bismuth mixture, 25 mixture, 616, 617, 618 injection, 752, 782 liniment, 834, 835 Croton oil pills, 51 and colocynth pills, 52 and potassa, 706 mixture, 66 saponaceous, 67 and oil of amber liniment, 700 liniment, 699 Cubebs and bismuth, 340 and carbolic acid inhalation, 258 and copaiba pills, 100 copaiba, etc., 128, 129 and ergot, 94 and soda, 339 mixture of, 132 Currant-jelly water, 976 Cyanide of potassium, 238 lotion, 831 and chloroform ointment, 900 DENTAL anesthetic, 396 Depilatory ointment, 928 powder, 940 De Valangin's solution and iron, 571 Dewees' tincture of guaiac, 278 carminative, 381 Diabetic bread, 988 Digitalin, 102 Digitalis, acetate of potassa, etc., 116 calomel and opium, 99 colchicum and colocynth pill, 48 and colchicum, 122 354: INDEX OF THE FORMULARY PROPER. Digitalis — myrrh and iron, 268 and opium, 355 podophyllin and iron, 98 quinia and colchicum pill, 45 squill and blue mass, 104 and juniper, 103 and spirits of nitre, 105 Discutient plaster, 936 Disinfecting mouth wash, 805 Diuretic wine, 114 drops, 113 Dogwood decoction, 504 Donovan's solution, 561 Dover's powder, antimony, and calomel, 187 and aconite, 361 and conium, 185 camphor and nitre, 147 Draught, effervescing, 159 Dulcamara and poppy fomentation, 965 Dupuytren's antisyphilitic pill, 421. antipsoric liniment, 849 Dyspeptic lye, 649 EGGS, cream, and beef, 1004 Egg-nogg, 344 Elaterin, tincture of, 84 Elaterium and colchicum, 121 pills, 50 Elixir of bismuth, 519 of cinchona, ferrated, 518 of cinchona, 517 Elm poultice, 947 Emetia, lozenges of, 2 mixture, 12 Emmenagogue suppository, 282 Emollient glycerin bath, 956 poultice, 948, 949 collyrium, 735 Enema of castor oil, molasses, and salt. 85 of oil of turpentine, 88 of ox gall, 87 of senna and Epsom salt, 89 of soap, 86 of tobacco, 90 Epsom salt and tartar emetic mixture. 68 magnesia, and colchicum, 72 and senna, 78 jalap, and nitric acid mixture, 69 Ergotine mixture, 275 Ergot and cinnamon, 613 and cubebs, 94 and savin, 263 Erigeron, oil of, 272 Essence of beef, 1002 Ether and camphor, 328 and turpentine, 144 Eupatorium, sage, and cascarilla, 493 infusion of, 172 FALK'S antacrid mixture, 584 Fennel seed and magnesia, 634 Fei'rocyanide of iron and guaiac, 434 Firing, 651 Flaxseed and bran poultice, 943 Flaxseed and sage gargle, 787 tea, 235, 973 Fothergill's pills, 47 GALLS, aromatic syrup of, 626 decoction of, 610 syrup of, and hydrochloric acid, 627 Gallic acid and morphia, 625 and opium, 724 pills, 603 Gamboge and jalap powder, 33 and calomel, 286 Garlic cataplasm, 683 and tolu, 202 Gelatine jelly, 1008 Gelsemium, 168 Gentian and aloes pill, 55 aloes, zedoary, etc., 516 and carbonate of magnesia, 139 cantharides, and ammonia, 276 and capsicum, 314 compound infusion, 501 and iron, 484 and orange-peel, 514 and soda, 647 and tar, 191 Geranium mixture, 614 Ginger and ammonia, 320 columbo, and iron, 462 and Colombo, 494 soda, and magnesia, 635 savin, and borax, 264 rhubarb, and senna, 77 Glycerin, ammonia, etc., 857 and borax, 856 and camphor liniment, 859 cream, 858 lotion, 862 and tannic acid lotion, 866 and morphia lotion, 863 and lead-water lotion, 864 morphia, and iodide of iron, 244 ointment, 873 Gondret's pommade ammoniacale, 693 Gossypium, decoction, 273 Granville's antidynous lotions, 692 INDEX OF THE FORMULARY PROPER 355 Griffitts's cathartic pills, 38 Griffith's myrrh mixture, 507 Guaiac, aloes, and rhubarb. 56 compound powder of, 155 nitre, etc., 165 and soda, 278 and turpentine, 313 and paregoric, 329 Gum and molasses mixture, 818 Guthrie's ointment, 739 HARROWGATE bath, artificial, 961 water, artificial, 583 Hartshorn liniment, 701 jelly, 1006 Hellebore, myrrh, and cantharides, 277 Hemp, Indian, decoction, 109 Hoffman's anodyne and laudanum, 414 Honey and borax wash, 792 sage, and alum gargle, 812 and sulphuric acid gargle, 810 Hooper's pills, 266 Hope's camphor mixture, 606 Hops, infusion, 500 and iodine inhalation, 251 and potassa, 135 and tar, 246 Hydrochlorate of ammonia and mer- cury, ointment, 888 Hydrochloric acid and cinchona gargle, 799 and syrup of galls, 627 and iron, 141 gargle, 813 mixture, 142 Hydrangea arborescens, 138 Hydrarg. cum creta, iron, and ipecac, 464 Hydrastis, injection, 775 Hydrocyanic acid and morphia, 21 and potassa lotion, 824 and wild cherry, 201 squill, and morphia, 207 Hyoscyamus and opium, 352 squill, and myrrh, 192 and ipecac, 351 Hyposulphite of soda, 582 douche, 756 Hypophosphites of lime, soda, etc., 245 ICELAND moss, 236 jelly, 992 Ignatia, aloes, and opium, 472 Instantaneous vesicant, 677 Iodide of arsenic, ointment, 885 of barium, oiutment, 881 of bromide of potassium, 567 Iodide — of cadmium, ointment, 882 of iron, 552 of iron, ointment, 883 of mercury, enema, 311 of mercury and potassa, 556, 557 of mercury, pills, 423, 424 of potassium and buchu, 180 of potassium, liniment, 283 of potassium and manganese, 483 of potassium, mixture, 555 of potassium, ointment, 878 of potassium and opium, liniment, 284 of potassium and sarsaparilla, 550 of sulphur, ointment, 884 Iodine and arsenic, 566, 569 and collodion, 877 and conium inhalation, 249 caustic glycerole of, 668 and calomel ointment, 886 and cod-liver oil, 578 ethereal solution, 705 ethereal tincture of, 549 and hops inhalation, 251 inhalation, 250 and iodide of potassium collyrium, 713 liniment, 833 mercury, and sulphur fumigation, 968 ointment, 876 and opium ointment, 892 and opium gargle, 808 paint, 704 poultice, 953 preparations, 548 tincture of, mixture of, 551 and tannin, collodion of, 285 waters, 559, 560 Ioduretted baths, 960 biniodide of mercury, 558 Ipecac and almond, 212 calomel, and sugar of lead, 588 iron, and mercury, 464 and hyoscyamus, 351 and myrrh, 182 mercury, and chalk, 429 ointment, 922 opium, and calomel, 152 calomel, and nitre. 151 and rhubarb powder, 938 soda, etc., 219 squill, and paregoric, 197 veratrura, and spirits of nitre, 198 wine of, and morphia, 156 and calomel, 7 powder, 1 syrup aud wine, 14 356 INDEX OF THE FOR3IULAEY PEOPEE Ipecac — and tartar emetic, powder of, 3 tartar emetic, and squill, 13 aud tartar emetic, wine of, 9 and sulphate of zinc, 6 Iron, aloes, and cloves, 269 and castor, 280 and podopkyllin, 478 and bismuth, 467 ammoniated, pills of, 473 ammonio-citrate, 524 ammonio-tartrate, 509 arseniate of, 540 bromide of, 544 Colombo, and ginger, 462 capsicum, etc., 479 and cinchona, 456 carbonate of, mass, 468 and quinia, 476 and chloride of barium, 179 digitalis, and podophyllin, 98 and elixir of vitriol, 510 and gentian, 484 and hydrochloric acid, 141 iodide of, 552 injection, 769 and manganese, 532 by hydrogen, 463 ipecac, and mercury, 464 jalap, and aloes, 266 lactate of, 469 lozenges, 295 myrrh, and digitalis, 268 and myrrh, 265 nux vomica, and cerium, 19 pill, Bretonneau's, 477 perchloride of. 622 and arsenic, 571 douche, 758 ' and nitric acid, 526 potassio-tartrate, 527 pernitrate of, 530 podophyllin and santonin, 291 protoxide of, 508 pyrophosphate of, 531 and quassia, 485 and quinia, citrate of, 474 quinia, and strychnia, syrup of, 533 and strychnia, 270, 471 subsulphate of, injection, 767 sulphate of, collyrium, 714 injection, 768 lotion, 867 and quinia, 475 tincture of chloride, 523 and acetic acid, 525 Itch liniment, 815 JACKSON'S lozenges, 195 pectoral syrup, 203, 204 Jalap, aloes, and blue pill, 39 and butternut pills, 46 and calomel powder, 26 calomel, and rhubarb, 29 and cream of tartar powder, 32 and gamboge powder, 33 iron, and aloes, 266 nitre, etc. electuary, 61 James' powder, 149 Juniper berries and cream of tartar, 106 Juniper, squill, etc., 115 squill, and digitalis, 103 KAMEELA, 294 Kentish's ointment, 905 Kino and opium, 600 Kirkland's neutral cerate, 917 Kousso, infusion of, 299 LACTUCARIUM and hemlock, 350 syrup of, 205 Lafayette mixture, 131 Lapis divinus, 711 Lartigue's gout pill, 48 Laudanum, 362 antimonial wine, and spirit of nitre, 164 assafcetida, and magnesia, 381 and catechu, 615 and colchicum, 83 enema, 385 and Hoffman's anodyne, 414 and sulphate of zinc, 762 and tartar emetic, 218 and turpentine, 366 Lead, acetate of, 629 and calomel, 587, 594 calomel, and ipecac, 588 gargle, 803 enema, 630 and opium, 595 and sulphate of zinc, 763 and benzoic acid ointment, 916 and calomel ointment, 907 and camphor, 821, 822 copper, and copal ointment, 932 and opium liniment, 852 and rose water, 743 subacetate of, and opium collyrium, 715 water and glycerin lotion, 864 Lemonade, 981 Lenitive electuary and cream of tartar, 59 INDEX OF THE FORMULARY PROPER. 357 Liebig's beef-tea, 1001 Lime, chloride of, gargle, 804 syrup of, 643 and zinc ointment, 927 water and linseed oil, 815 and milk, 642 and sulphuret of potassium, 826 and zinc lotion, 814 Linimentum album, 837 crinale, 860 Linseed oil and lime water, 815 Liquid deodorant, 820 Lithia, carbonate of, injection, 146 Lobelia, squill, and belladonna, 222 and prussic acid, 239 Lobstein's phosphorated ether, 333 Logwood and catechu, 611 Lugol's solutions, 553 rubefacient solution, 703 Lunar caustic, 657 Lupulin pills, 348 mixture, 367 MAGNESIA, ammonia, etc., 645 assafoetida, and laudanum, 38 and bismuth, 590 calcined, 31 carbonate and gentian, 139 charcoal, and ginger, 637 citrate of, solution, 75 and Colombo, 636 and colchicum mixture, 71 Epsom salt, and colchicum, 72 and fennel seed, 634 and rhubarb mixture, 70 and rhubarb powder, 30 soda, and ginger, 635 and sulphur, 35 water, 644 Magendie's iodine solution, 554 Maizena, 995 Male fern, mixture, 306 powder, 293 Malt infusion, 980 Manganese, iodide of, and iron, 532 and iodide of potassium, 483 Manna and senna, 79 senna, and rhubarb, 81 Marcet's beef tea, 1003 Mastich and pellitory, 430 Matico, 604 Meigs' food for infants, 997 Mel iEgyptiacum, 807 Mercurial cerate, 899 ointment and camphor, 688 gargle, 801 inhalation, 255 Mercurial — pill, quinia, and aloes, 537 vapor bath, 969 Mercury, ammoniated, and sulphur, ointment, 895 acid nitrate, caustic, 664 bichloride of, 539 collyrium, 727 bath, 958 caustic of, 662 and tartar emetic, lotion, 691 injection, 761 lotion, 828 mixture, 579 and opium, 734 and camphor ointment, 894 and carbolic acid ointment, 911 chalk, and ipecac, 429 cyanide of, 428 ointment, 893 iodide of, and potassa, 556, 557 ioduretted biniodide of, 558 and muriate of ammonia ointment, 887 oxide of, and sulphate of zinc, oint- ment, 741 guaiacum, and turpentine, 584 red iodide of, 538 red oxide of, 427 red iodide of, ointment, 889, 890, 891 red oxide, ointment, 875 and oxide of zinc, collyrium, 709 sulphur and iodine fumigation, 968 Mettauer's aperient, 82 Mezereon decoction, 177 Milk punch, 345 Mitchell's aperient pill, 49 tonic pills, 480 Molasses and gum mixture, 818 Monsel's solution, 623 Monsel solution injection, 767 Morphia, arsenic, and cascarilla, 568 and borax lotion, 868 and calomel powder, 16 camphor, etc., 357 colocynth and colchicum pill, 44 and gallic acid, 625 glycerine and iodide of iron, 244 and glycerin lotion, 863 and hydrocyanic acid, 21 and naphtha, 225 and prussic acid, 21 and quinia enema, 460 spirit of nitre, etc., 162 squill and prussic acid, 207 and sulphuric acid, 22 sulphate of, pills, 349 358 INDEX OF THE FORMULARY PROPER. Morphia, sulphate of, — solution, 364 syrup, 365 squills and tolu, 242 suppository, 389 and tannic acid, 602 tolu and tartar emetic, 243 turpentine, etc., 241 •wild cherry, etc., 217 and wine of ipecac, 156 and veratria ointment, 930 Moxa, 671 Mucilage of gum arabic, 977 Muriate of ammonia and acetic acid gargle, 802 Muriatic acid mixture, 142 Mush poultice, 944 Musk and camphor, 409 mixture, 411 Mustard fomentation, 966 injection, 784 pepper and ginger cataplasm, 685 plaster, 682 powder of, 5 whey, 341 Mutton broth, 999 Myrrh and borax gargle, 791 and camphor, 326 cantharides and hellebore, 277 and ipecac, 182 and iron, 265 iron and digitalis, 268 squill and henbane, 192 and sulphate of zinc, 184 XT APHTHA and bloodroot, 224 j\ and morphia, 225 Naphthaline mixture, 214 ointment, 919 Neutral mixture, 157 Nitrate of silver collyrium, 719 and atropia collyrium, 740 mixture, 521, 619 solution, 746, 747, 759 ointment, 931 pills, 481, 482 Nitre, calomel, and opium, 183 opium, and ipecac, 151 cream of tartar, and tartar emetic, 92 Dover's powder, and camphor, 147 jalap, etc., electuary, 61 spirit of, and morphia, etc., 162 guaiacum, etc., 165 senna, and sulphur electuary, 60 and squill powders, 91 tartar emetic, and calomel, 150 Nitric acid, 581 Nitric acid — and ammoniac, 232 mixture, 416 Nitric and sulphuric acids, 512, Nitro-muriatic acid, mixture, 140, 580 bath, 957 Nitro-hydrochloric acid mixture, 1 40 Nitrous powders, 150 Nux vomica, 359 cerium and iron, 19 iron, and arsenic, 491 liniment, 848 OAK BARK and alum gargle, 789 Oatmeal gruel, 982 Odontalgic lotion, 794 Oil of cade ointment, 914 Oil of juniper mixture, 113 Oleo-saccharoles, 346 Oleaginous mixture, 62, 63 Olive oil and camphor enema, 310 Olive ointment, 912 Onion poultice, 684 Opiate liniment compound, 850, 851 Opium and acetate of ammonia, 733 aloes, and ignatia, 472 and alum, 589 alum, and catechu, 596 and arsenic, 443 and arsenite of potassa, 459 and belladonna plaster, 402 and bichloride of mercury, 734 bismuth, and calomel, 591 calomel, and nitre, 183 and quinia, 536 and ipecac, 152 and calomel collyrium, 710 and camphor, 354 collyrium, 728 plaster, 401 and chalk, 632 and colocynth, 353 and creasote, 598, 599 and digitalis, 355 digitalis and calomel, 99 and gallic acid, 724 and hyoscyamus, 352 and iodide of potassium liniment, 284 injection, 760 and iodine ointment, 892 ipecac, calomel, and nitre, 151 and kino, 600 lime-water, etc., 395 and lead liniment, 852 and phosphoric acid, 267 pills, 347 preparation of, 363 INDEX OF THE FORMULARY PROPER. 359 Opium — quinia and pepper, 436 and rhatany suppository, 388 suppository, 386, 387 and subacetate of lead collyrium, 715 and sugar of lead, 595 and sulphate of copper, 445 and sulphate of soda, 620 and tannic acid, 601 and tartar emetic, 186 and tannic acid ointment, 935 and tar ointment, 913 uva ursi, and cinchona, 133 wine of, collyrium, 737 Origanum and camphor liniment, 855 Oxalate of cerium pills, 18 Oxide of silver and aromatic powder, 586 Ox-gall and calomel, 545 enema, 87 pills, 58 PANADO, 985 Paregoric and guaiacum, 329 Paregoric, ipecac, and squill, 197 squill, and ammonise, 226 tolu, and conium, 211 Pareira brava decoction, 110 Parrish's camphor mixture, 605 Parsley infusion, 107 Pea issue, 673 Pearson's solution, 570 Pellitory and mastich, 430 Pepsin and aloes, 490 Pepsine, elixir of, 534 Peristaltic persuaders, Chapman, 53 Permanganate of potassa, douche, 754 injection, 772 lotion, 819 and iodide of zinc douche, 755 Petroleum and camphor liniment, 854 Phosphorated ether, Lobstein's, 333 oil, 334 Phosphoric acid and columbo, 143 Phosphorus, glycerole of, 335 Phosphoric acid lotion, 827 and opium, 267 Phosphorus emulsion, 332 Plasma, 872 Pleurisy root, infusion of, 173 Plummer's pill, 175 Podophyllin, aloes, and iron, 478 and alum pill, 43 and colocynth pill, 42 digitalis, and iron, 98 santonin, and iron, 291 Pomegranate and alum gargle, 796 and chlorate of potassa gargle, 797 Pomegranate — decoction of, 298 Poppy and bittersweet fomentation, 965 Poppies and camphor, 736 Potassa in milk, 111 carbonate, mixture, 640 caustic, solution, 694 citrate of, solution, 158 and squill, 123 and croton-oil liniment, 706 cum calce, 653 and hydrocyanic acid lotion, 824 nitrate of, mixture, 166 permanganate, injection, 781 and tincture of hops, 135 Powders, Seidlitz, 36 Propylamin, 369, 370, 371 Prunes and senna, 80 Prussic acid, 237 collyrium, 723 and lobelia, 239 and morphia, 21 squill, and morphia, 207 and wild cherry, 201 Pumpkin seeds, emulsion, 308 Pyroligneous acid, 749 ether, and turpentine, 751 Pyroxylic spirit, 24 QUxASSIA and bicarbonate of soda, 136 infusion, 498 and iron, 485 Quinia and ammonia, 438 blue pill, and aloes, 537 calomel, and opium, 536 castor oil, etc., hair-wash, 861 and cod-liver oil, 577 digitalis, and colchicum pill, 45 ferrocyanate, 453 and iron, citrate of, 474 iron, and strychnia, syrup of, 533 opium, and pepper, 436 and morphia enema, 460 sulphate of, 435 sulphate of, gargle, 790 sulphate of, injection, 770 sulphate of, solution, 449, 450 and tartar emetic, 437 and tartaric acid, 454 and sulphate of iron, 475 solution for hypodermic injection, 461 valerianate of, 316 and Vallet's mass, 476 Quinidia, sulphate of, 441 and tannic acid, 455 Quince seed, decoction, 729 860 INDEX OF THE FORMULARY PROPER EACAHOUT des Arabes, 987 Raw beef preparation, 1005 Rennet whey, 1015 Resolvent poultice, 951 Rhatany gargle, 798 mixture, 628 and opium suppository, 388 and rhubarb, 597 Rhubarb, aloes, and guaiac, 56 blue pill, and soda, 40 calomel, and jalap, 29 and calomel powder, 27 columbo, etc., 495 and crabs' claws, 633 and ipecac powder, 938 and magnesia mixture, 70 and magnesia powder, 30 senna, and manna, 81 and rhatany, 597 senna, and ginger, 77 soda, etc., 638 and sulphate of iron, 57 and wormseecl, 302 Rice flour gruel, 984 water, 972 Ricord's pills, 424 Rose water and lead, 743 Rosin inhalation, 253 SAGE, boneset, and cascarilla, 493 and flaxseed gargle, 787 honey, and alum gargle, 812 tea, 979 Sago, 989 Sal-ammoniac mixture, 572 squill, etc., 213 Salep powders compound, 986 Salicine powders, 442 Saline powders, Stevens', 37 Salt and capsicum, 338 and cochineal, 289 poultice, 952 of tartar and ammonia, 641 of tartar, columbo, etc., 646 of tartar mixture, 640 Sanguinarina powder, 941 Santonin lozenges, 292 podophyllin, and iron, 291 powders, 290 spigelia, and senna, 305 Saponaceous fomentation, 963 Sarsaparilla decoction, 178 beer, 181 Savin, borax, and ginger, 264 and cantharides, 262 and ergot, 263 senna, and pinkroot, 288 Savin — and sulphate of potassa, 261 and verdigris powder, 939 Scudamore's iodine inhalation, 250 mixture, 72 Sedative lotion, 398 Seidlitz powders, 36 Senega, ammoniac, and tolu, 209 decoction of, 271 squill, and ipecac, 196 squill, and tartar emetic, 208 Senna and Epsom salt, 78 ginger, and rhubarb, 77 and manna, 79 pinkroot, etc., 297 and prunes, 80 rhubarb, and manna, 81 savine, and pinkroot, 288 spigelia, and santonin, 305 sulphur, and nitre, electuary, 60 Serpentaria, aloes, and canella, 260 and cinnabar, 174 infusion, 497 Seton, 674 Silver, iodide of, 543 nitrate of, 619 pills, 481, 482 solution, 746, 747, 759 mixture, 521 ointment, 931 and atropia, collyrium, 740 oxide of, 489 oxide of, ointment, 926 Sinapism, 682 Soap and carbonate of soda, 134 liniment, sulphuretted, 846 Soda, bicarbonate of, and copaiba, 137 bicarbonate of, and quassia, 136 carbonate of, and calomel, 154 carbonate of, injection, 145 carbonate of, and soap, 134 and calomel powder, 28 and chloroform, 23 and cubebs, 339 ipecac, etc., 219 and gentian, 647 mint, 648 magnesia, and ginger, 635 rhubarb, etc., 638 rhubarb, and blue pill, 40 taraxacum, etc., 108 and uva ursi, 93 water, purgative, 76 Solutio vitriolica, Moseley's, 11 Spermaceti mixture, 233 ointment, 874 Spice plaster, 686 Spirit of mindererus and antimonial wine, 160 INDEX OF THE FORMULARY PROPER, 361 Spirit — of nitre and acetate of ammonia, 161 of nitre and antimonial wine, 163 of nitre, antimonial wine, and lau- danum, 164 of nitre and digitalis, 105 of nitre, ipecac, and veratrum, 198 pyroxylic, 24 Spigelia and calomel, 287 senna, and santonin, 305 savin, and senna, 288 senna, etc., 297 Spitta's lozenges, 194 Sponge, burnt, 546 Squill and ammoniac, 210 ammoniac, and coniuni, 188 ammoniac, and paregoric, 228 and calomel, 97 calomel, and ammoniac, 189 and citrate of potassa, 123 digitalis, and blue mass, 104 digitalis, and juniper, 103 ipecac, and paregoric, 197 juniper, etc., 115 ipecacuanha, and tartar emetic, 13 lobelia, and belladonna, 222 morphia, and prussic acid, 207 morphia, and tolu, 242 mixture of, 206 myrrh, and henbane, 192 an,d nitre powders, 91 sal-ammoniac, etc., 213 senega, and ipecac, 196 tartar emetic, and cream of tartar, 95 tartar emetic, and senega, 208 Starch mucilage, 1013 Stevens' saline powders, 37 Stimulant fomentation, 962 Stokes' liniment, 837 Stramonium inhalation, 256 in milk, 397 Strychnia and bismuth, 492 and bismuth pills, 17 collyrium, 725 injection, 780 and iron, 270, 471 iron, and quinia, syrup of, 533 mxture, 372 Succinic acid and castor, 408 Suet ptisan, 1012 Sulphate of copper and cinchona, 444 of copper and opium, 445 of iron and rhubarb, 57 of potassa and savin, 261 of soda ard chloroform, 621 of soda and opium, 620 Sulphate — of zinc and alum mixture, 11 of zinc and ipecacuanha, 6 of zinc and myrrh, 184 Sulphite of soda, 748 wash, 869 Sulphur and cream of tartar powder, 34 and magnesia, 35 senna, and nitre, electuary, 60 mercury, and iodine fumigation, 968 ointment, 898 ointment, aromatic, 918 ointment, compound, 896 and white precipitate ointment, 895 Sulphureous bath, 954 Sulphureo-gelatinous bath, 955 Sulphuret of antimony and calomel, 153 of potassium and lime-water, 826 of potassium lotion, 825 Sulphuretted soap liniment, 846 Sulphuric acid, caustic, 663 gargle, 800 and honey gargle, 810 and iron, 510 mixture, 511 and morphia, 22 and nitric acid, 512 Sumbul and valerian, 412 T ANNATE of lead ointment, 935 Tannic acid and quinidia, 455 Tannic acid and glycerin lotion, 866 and morphia, 602 and opium, 601 pessary, 785 and opium ointment, 933 ointment, 934 suppository, 631 and atropia collyrium, 726 Tannin injection, 779 and iodine, collodion of, 285 Tapioca jelly, 990 Tar and calomel ointment, 923 and citrine ointment, 909 and gentian, 191 and hops, 246 inhalation, 252 oil of, 231 and opium ointment, 913 pills of, 547 water, 230 Taraxacum and blue mass, 101 soda, etc., 108 Tartar emetic and opium, 186 nitre, and calomel, 150 362 INDEX OF THE FORMULARY PROPER. Tartar emetic — mixture, 10 and ipecacuanha, wine of, 9 and ammonia liniment, 842 and quinia, 437 ointment, 690 and corrosive sublimate lotion, 691 senega, and squill, 208 and laudanum, 218 nitre, and cream of tartar, 92 morphia, and tolu, 243 ipecacuanha, and squill, 13 and ipecacuanha, powder of, 3 plaster, 689 squill, and cream of tartar, 95 Tartaric acid and quinia, 454 Tartar whey, 1018 Tea injection, 776 Tin, electuary of, 300 Toast water, 974 Tobacco enema, 90 fomentation, 967 Tolu, ammoniac, and senega, 209 and belladonna, 234 and copaiba, 228 conium, and paregoric. 211 and ether inhalation, 248 and garlic, 202 inhalation of, 247 morphia, and squill, 242 and tartar emetic, 243 and oil of amber, 215 and wine of antimony, 167 Tonic laxative infusion, 502 Tous les mois, 994 Turpentine and ether, 144 and guaiac, 313 linctus of, 307 liniment, 696 mixture, 64, 323 morphia, etc., 241 oil of, 118 Tyson's antimonial powder, 148 u VA URSI and buchu, 126 and soda, 93 cinchona, and opium, 133 YTALERIAN, assafcetida, and castor, V 415 and Bestucheffe's tincture, 529 and cinchona, 505 cinchona, etc., 515 and cajeput, 322 and sumbul, 412 and carbonate of ammonia, 319 Valerianate of ammonia, elixir of, 321 Valerianate — of quinia, 316 of zinc pills, 410 Vegetable soup, 998 Venice turpentine, calomel, etc., 296 Veratria, acid solution of, 73 and morphia ointment, 930 ointment, 929 Veratrum and aconite, 171 ipecac, and spirits of nitre, 198 Verdigris and calomel powder, 937 ointment, 921 and savin powder, 939 Vienna paste, 653 with morphia, 655 with opium, 654 Vinegar and alcohol collyrium, 716 draught, 513 whey, 1017 Volatile liniment, 701, 841 WILD CHERRY and bloodroot, 216 H infusion, 496 and morphia, 217 and prussic acid, 201 Wine and egg mixture, 343 mulled, 1014 whey, 342 Wistar's cough lozenges, 193 Worm tea, 297 YEAST mixture, 330 poultice, 945 Yellow wash, 829 yEDOARY, aloes, gentian, etc., 516 [j Zinc, acetate of, injection, 765 Zinc, acetate of, collyrium, 717 chloride of, caustic, 659, 661 injection, 766 iodide of, gargle, 809 lactate of, 487 and lime ointment, 927 and lime-water lotion, 814 oxide of, 486 ointment, 904 and red precipitate collyrium, 709 and sugar collyrium, 708 • sulphate of, and acetate of lead, 763 and calomel ointment, 903 etc., gargle, 793 and laudanum, 762 and red precipitate ointment, 741 INDEX OF DISEASES AND THEIR REMEDIES. The figures indicate the number of the Formula. ABSCESSES, flaxseed and bran poul- tice, 9-13 indolent, resolvent poultice, 951 frontal, iodide of zinc and perman- ganate of potassa, 755 Acidity of stomach, crabs' claws and rhubarb, 633 dyspeptic lye, 649 tonic laxative infusion, 502 of pregnancy, chloroform and soda, 23 Acne, lime and zinc ointment, 927 sulphite of soda, 869 Albuminuria of pregnancy, benzoic acid mixture, 120 Alopecia, ammonia, glycerin, etc., 857 cantharidine and castor oil, 860 quinia, castor oil, etc., 861 Amaurosis, phosphorus, 332, 333 strychnia collyrium, 725 Amenorrbcea, aloes, canella, and ser- pentaria, 260 aloes, sulphate of iron, and cloves, 269 ammonio-citrate of iron, 524 decoction of senega, 271 digitalis, myrrh, and iron, 268 emmenagogue suppository, 282 guaiacum and copaiba, 279 hellebore, myrrh, and cantharides, 277 hiera picra, 281 Hooper's pills, 266 iron, aloes, and castor, 280 iron and myrrh, 265 iron and strychnia, 270 mustard injection, 784 savin, borax, and ginger, 264 savin and cantharides, 262 savin and ergot, 263 savin and sulphate of potassa, 261 Anaemia, ammonio-tartrate of iron, 509 sulphuric acid mixture, 511 steel wine, 527 pyrophosphate of iron, 531 iron and sulphuric acid. 510 sulphate of iron and quinia, 475 peracetate of iron, 525 arsenic, iron, and nux vomica, 491 Bretonneau's iron pill, 477 iron and gentian, 484 iodide of iron and manganese, 532 lactate of iron, 469 ferrated elixir of cinchona, 518 iron reduced, 463 Vallet's mass, 468 Aphonia, atomized fluids, 259 Aphthous stomatitis, borax and honey, 792 sulphuric acid and honey, 810 Arthritis, anodyne plaster, 400 chronic, anodyne fomentation, 964 iodide of cadmium, 882 Ascarides, aloetic enema, 309 anthelmintic clyster, 311 enema ofcamphorand sweet oil, 310 Ascites, digitalis, calomel, and opium, 99 Asthma, atomized fluids, 259 lobelia and prussic acid, 239 opium and digitalis, 355 ' squill, ammoniac, and conium, 188 stramonium inhalation, 256 Atony, elixir of aloes, zedoary, etc., 516 elixir of cinchona, 517 general, syrup of iron, quinia, and strychnia, 533 BALDNESS, see Alopecia. Bilious fever, Griffith's pill, 38 Bilious vomiting, calomel and bismuth, 15 364 INDEX OF DISEASES AND THEIR REMEDIES. Bladder, irritation of, flaxseed tea, 973 irritability of, mixture of bicarbon- ate of soda, etc., 137 potassa in milk, 111 Bronchial irritation, tar water, 230 conium and Dover's powder, 185 calomel, squill, and ammoniac, 189 Jackson's lozenges, 195 oil of amber and tolu, 215 Spitta's lozenges, 194 Wistar's cough lozenges, 193 Bronchitis, atomized fluids, 259 sal ammoniac, squill, etc., 213 acute, antimony, calomel, and Do- ver's powder, 187 flaxseed-tea, 235 Jackson's pectoral syrup, 203, 204 ipecac, veratrum, and spirits of nitre, 198 Iceland moss, 236 nitre, calomel, and opium, 183 squill, ipecac, and paregoric, 197 squill, senega, and ipecac, 196 tolu and belladonna, 234 chronic, inhalation of ether and tolu, 248 inhalation of rosin, 253 inhalation of tar, 252 balsam of Peru, 229 ammoniac, castor, etc., 240 senega, ammoniac, and tolu, 209 oil of tar, 231 almond emulsion and ipecac, 212 ammoniac, squill, and pare- goric, 226 tar water, 230 tar and gentian, 191 tartar emetic and opium, 186 syrup of lactucarium, 205 morphia and wild cherry, 217 myrrh, squill, and henbane, 192 squill, ammoniac, and conium, 188 bloodroot and wild cherry, 216 calomel, squill, and tartar emetic, 190 myrrh, ipecac, etc., 182 ammoniac and squill, 210 naphtha and morphia, 225 copaiba and tolu, 228 inhalation of iodine and hem- lock, 249 arsenical inhalation, 254 inhalation of tolu, 247 Bronchitis, chronic — inhalation of chlorine, 257 inhalation of iodine, '250 inhalation of iodine and hops, 251 infantile, garlic and tolu, 202 mixture of squill, 206 senile, myrrh, ipecac, etc., 182 Bronchocele, burnt sponge, 546 Bruises, see Sprains. Buboes, mercury with opium, 894 Burns, Kentish ointment, 905 creasote and charcoal, 924 spermaceti ointment, 874 oxide of zinc ointment, 904 Kirkland's cerate, 917 gum and molasses, 818 carron oil, 815 carbolic acid and castor oil, 925 sloughing, carron oil and carbolic acid, 816 recent, carron oil and aconite, 817 of the eye, corrosive sublimate and opium, 734 CANCER, arseniate'of iron, 540 arsenic and iron, 571 uterine, creasote injection, 782 permanganate of potassa, 781 Cancrum oris, sulphate of copper, 811 Carbuncle, carron oil and carbolic acid, 816 Cardiac nausea, prussic acid and mor- phia, 21 Catarrh, chronic, bloodroot and wild cherry, 216 ammoniac and nitric acid, 232 spermaceti mixture, 233 atomized fluids, 259 copaiba and tolu, 228 naphthaline, 214 morphia and wild cherry, 217 oil of tar, 231 infantile, croton oil and amber, 700 onion poultice, 684 nasal, perchloride of iron, douche, 758 senile, ammoniac and squill, 210 ammoniac, squill, and pare- goric, 226 Cerumen, deficient, pyroligneous acid, ether, and turpentine, 751 Chaps, glycerin lotion, 862 glycerin ointment, 873 glycerin cream, 858 borax and glycerin, 856 Chlorosis, ammonio-tartrate of iron, 509 iron, capsicum, etc., 479 IXDEX OF DISEASES AND THEIE EEMEDIES. 365 Chlorosis — cantharides, ammonia, and gentian, 276 Colombo and iron, 465 ipecac, iron, and mercury, 464 iron and myrrh, 265 iron and strychnia, 471 sulphate of iron and quinia, 475 Cholera, anaesthetic pill, 357 camphor and ether, 828 cannabis, 383 chloroform mixture, 375, 378 Jackson's mixture, 609 London mixture, 608 Stevens' powders, 37 infantum, acetate of lead, 629 aromatic syrup of blackberry, 612 bismuth and iron, 467 calomel, opium, and bismuth, 591 nitrate of silver, 619 sugar of lead and calomel, 587 sugar of lead, calomel, and ipecac, 588 morbus, camphor and ether, 328 Parrish's camphor mixture, 605 Chordee, morphia suppository, 389 Chorea, cimicifuga, 417 Lugol's and Fowler's solution, 566 nitrate of silver, 482 oxide of zinc, 486 Colic, anesthetic pill, 357 chloroform mixture, 375, 378 infantile, carminative, 382 Dewees' carminative, 381 soda mint, 648 nephritic, oil of turpentine, 118 turpentine and ether, 144 Colica pictonum, opium and colocynth, 353 Condylomata, calomel and sulphate of zinc, 903 Conjunctivitis, acute, emollient colly- rium, 735 granular, atropia and tannin, 726 Constipation, atonic, rhubarb and sul- phate of iron, 57 habitual, tonic laxative infusion, 502 aloes and gentian, 55 Bretonneau's iron pill, 477 mixture of butternut, 74 podophyllin, aloes, and iron, 478 lenitive electuary and cream of tartar, 59 Constipation — obstinate, Chapman's peristaltic persuaders, 53 croton oil and colocynth, 52 of pregnancy, senna and prunes, 80 with impaction, ox-gall enema, 87 soap enema, 86 Contagious diseases, hyposulphite of soda, 582 Contusions, chloroform and aconite lini- ment, 406 Convulsions, infantile, assafoetida ene- ma, 418 onion poultice, 684 Corneal opacity, oxide of zinc and sugar, 708 oxide of zinc and red precipi- tate, 709 sulphate of cadmium, 720 specks, opium and calomel, 710 ulceration, iodine and iodide of po- tassium, 713 nitrate of silver and atropia, 740 Cough, atomized fluids, 259 spasmodic, assafoetida mixture, 223 assafoetida and acetate of am- monia, 227 Cramp, camphor and chloroform, 327 chloroform mixture, 375, 378 Croup, atomized fluids, 259 bloodroot and naphtha, 224 senega, squill, and tartar emetic, 208 Cystitis, soda and uva ursi, 93 chronic, buchu and acetate of po- tassa, 125 buchu and uva ursi, 126 copaiba and cubebs, 100 hydrangea arborescens, 138 DELIRIUM TREMENS, laudanum and turpentine, 366 lupulin, 367 Depression, vital, carbonate of ammonia, 317 stimulant fomentation, 962 Diabetes, alum whey, 624 Camplin's bread, 988 Diarrhoea, opium and tannic acid, 601 Tarrish's camphor mixture, 605 Castanello's powders, 986 aromatic syrup of galls, 626 kino and opium, 600 tincture of chloride of iron, 523 chalk mixture, 607 decoction of galls, 610 logwood and catechu, 611 366 INDEX OF DISEASES AND THEIR REMEDIES. Diarrhoea — catechu and laudanum, 615 compound alum powder, 585 rhatany and rhubarb, 597 mixture of bismuth, 520 chalk and opium, 632 compound chalk mixture, 639 sulphuric and nitric acids, 512 alum and opium, 589 acute, chloroform and sulphate of soda, 621 creasote and opium, 598, 599 chronic, bismuth, 466 creasote mixture, 617 Colombo and ginger, 494 Colombo and rhubarb, 495 pernitrate of iron, 530 infantile, bismuth, 592, 593 elixir of bismuth, 519 hydrochloric acid and galls, 627 flour food, 996 Meigs' food for children, 997 magnesia water, 644 magnesia and rhubarb, 70 sulphate of soda and opium, 620 nitrate of silver, 521 tubercular, bismuth and iron, 467 bismuth and magnesia, 590 Dilatation of pupil, Calabar bean, 394 Diphtheria, atomized fluid, 259 Dropsy, diuretic wine, 114 compound infusion of taraxacum, 108 ipecac, tartar emetic, and squill, 13 mixture of juniper, squill, etc., 115 decoction of apocynum, 109 digitalis, squill, and blue mass, 104 mixture of oil of juniper, 113 antiraonial wine, spirit of nitre, and laudanum, 164 digitalin, 102 parsley infusion, 107 cream of tartar, tartar emetic, and | squill, 95 digitalis and spirits of nitre, 105 jalap and cream of tartar, 32 tincture of elaterin, 84 squill and nitre, 91 jalap and gamboge, 33 abdominal, digitalis, calomel, and opium, 99 of aneemia, digitalis, podophyllin, and iron, 98 cardiac, digitalis and acetate of potassa, 116 digitalis, squill, and juniper, 103 Dropsy — with debility, cider mixture, 112 infusion of juniper and cream of tartar, 106 hepatic, taraxacum and blue mass, 101 squill and calomel, 97 thoracic, colchicum and digitalis, 122 digitalis, calomel, and opium, 99 elaterium and colchicum, 121 Dysentery, matico infusion, 604 powders of calomel, opium, &c, 152 chalk mixture, 607 logwood and catechu, 611 gum water, 977 bran tea, 978 morphia and tannic acid, 602 laudanum enema, 385 sulphate of zinc and alum, 11 Hope's mixture, 606 butternut and jalap, 46 chronic, geranium, 614 rhatany mixture, 628 Dysmenorrhcea, camphor, 274 camphor and myrrh, 326 camphor julep, 325 cotton root, 273 Dewees' tincture of guaiacum, 278 Falk's antacrid mixture, 584 morphia suppository, 389 opium suppository, 386, 387 Dyspepsia, angustura bark, 503 dogwood bark, 504 tonic laxative infusion, 502 Colombo, ginger, etc., 462 chamomile and orange-peel, 499 charcoal, magnesia, and ginger, 637 soda, rhubarb, etc., 638 Colombo and iron, 465 iron and quassia, 485 cinchona and iron, 488 iron and strychnia, 471 elixir of pepsin, 534 pepsin and aloes, 490 elixir of bismuth, 519 ignatia, aloes, and opium, 472 gentian and orange-peel, 514 hops, 500 infusion of gentian, 501 Chapman's antidyspeptic pills, 54 Mitchell's tonic pills, 480 magnesia, fennel, and cinnamon, 634 with acidity, Mettauer's aperient, 82 INDEX OF DISEASES AND THEIE EEMEDIES. 367 Dyspepsia — bilious, hydrarg. cum creta and ipecac, 429 ECZEMA, chloroform ointment, 915 oil of cade, 914 iodide of sulphur, 884 chronic, arsenic, morphia, and cas- carilla, 568 coal-tar ointment, 910 arsenic and iodine, 569 lotion of bismuth, 865 mercury and carbolic acid, 911 pills of tar, 547 potassa and hydrocyanic acid, 824 infantile, arsenic and iron, 522 Endometritis, chronic, iodine liniment, 283 liniment of iodine and opium, 284 Epilepsy, ammoniated copper, 470 bromide of potassium, 564 bromine and bromide of potassium, 565 lactate of zinc, 487 Magendie's solution of iodine, 554 nitrate of silver, 481, 482 oxide of zinc, 486 phosphorus, 332, 333 valerianate of zinc, 410 Epistaxis, alum douche, 757 perchloride of iron douche, 758 Erosions, Kirkland's cerate, 917 Erysipelas, elm poultice, 947 sulphate of iron, 867 tincture of chloride of iron, 523 sloughing, yeast poultice, 945 Erythema, benzoic acid and lead, 916 carron oil and aconite, 817 dulcamara and poppy fomentation, 965 oxide of zinc ointment, 904 plasma, 872 Excoriations, borax and glycerin, 856 glycerin lotion, 862 ointment, 873 and camphor, 859 FAVUS, compound sulphur ointment, 896 Fevers, currant-jelly water, 976 apple water, 975 malt infusion, 980 sage tea, 979 nitrate of potassa mixture, 166 toast water, 974 Fevers — James's powder, 149 Tyson's antimonial powder, 148 acetate of morphia and nitre, etc., 162 aconite and veratrum viride, 171 antimonial wine, spirit of nitre, and laudanum, 164 and spirit of nitre, 163 acetate of ammonia and spirit of nitre, etc., 161 acetate of ammonia and antimonial wine, 160 compound powder of guaiacum, 155 effervescing draught, 159 Dover's powder, camphor, etc., 147 gelsemium mixture, 168 lemonade, 981 neutral mixture, 157 nitrous powders, 150 soda powder of Guy's Hospital, 154 solution of citrate of potassa, 158 of morphia and wine of ipe- cacuanha, 156 butternut and jalap, 46 asthenic, brandy mixture, 1016 camphor mixture, 324 egg-nogg, 344 infusion of quassia, 498 of serpen taria, 497 milk punch, 345 mustard whey, 341 oil of turpentine, 323 wine whey, 342 wine and egg mixture, 343 yeast mixture, 330 bilious, calomel, quinia, and opium, 536 Griffith's pill, 38 catarrhal, boneset, 172 pleurisy root, 173 tolu and wine of antimony, 167 congestive, ipecac and rhubarb, 8 eruptive, ipecac and calomel, 7 hectic, sage, boneset, andcascarilla, 493 inflammatory, powders of opium, ipecac, etc. etc., 151 intermittent, arsenic and opium, 443 cinchona and citrate of potas- sa, 457 chinoidine, 439 decoction of cinchona, 447 Fowler's solution and opium, 459 cinchonia, 440 cinchona, 431 cloves and cream of tar- tar, 432 368 INDEX OF DISEASES AND THEIR REMEDIES, Fevers, intermittent — cinchona, serpentaria, and soda, 433 boneset, 172 prussian blue and guaiac, 434 extract of cinchona and carda- mom, 458 cinchonia and iron, 456 cinchona mixture, 448 quinia and ammonia, 438 and tartaric acid, 454 and morphia enema, 460 and tartar emetic, 437 opium and pepper, 436 ferrocyanate of quinia, 453 sulphate of quinia, 435, 449, 450, 451, 452 quinia hypodermically, 461 quinidia, 441 and tannic acid, 455 sulphate of bebeerine, 446 of copper and opium, 445 and cinchona, 444 salicine, 442 malignant, chlorinated lime, 337 nervous, sumbul and valerian, 412 puerperal, creasote injection, 782 permanganate of potassa, 781 Flatulence, ipecac and henbane, 351 oleo-saccharoles, 346 soda and cubebs, 339 and gentian mixture, 647 Foetor oris, alum gargle, 795 GANGRENE, liquid deodorant, 820 permanganate of potassa, 819 yeast poultice, 945 of lungs, atomized fluids, 259 Gastric debility, capsicum and gentian, 314 depression, effervescing ammonia mixture, 318 morphia and sulphuric acid, 22 strychnia and bismuth, 17 irritation, bismuth and cubebs, 340 calomel, 535 and morphia, 16 irritability, calomel and bismuth, 15 Gastritis, rice water, 972 chronic, iodide of silver, 543 nitrate of silver, 481 Gastrodynia, bismuth, 466, 593 elixir of bismuth, 519 mixture of bismuth, 520 magnesia and columbo, 636 soda and ginger, 635 nitrate of silver, 481 Glandular swellings, iodide of barium, 881 iodide of iron, 552 of mercury, 891 of potassium, 878 of zinc, 880 iodine and collodion, 877 morphia and iodide of mercury, 888 mercury and ammonia, 887 Gonorrhoea, acetate of zinc, 765 ammoniated copper, 778 chlorate of potassa, 771 calomel injection, 773 copaiba injection, 777 chloride of zinc, 766 sulphate of iron, 668 acetate of lead and sulphate of zinc, 763 chronic, Lafayette mixture, 131 mixture of copaiba, 127 cubebs, etc., 128, 129 hydrastis, 775 acute, nitre, cream of tartar, and tartar emetic, 92 muriate of ammonia, 764 nitrate of silver, 759 ointment, 931 sulphate of zinc and laudanum, 762 of copper, 774 iodide of iron, 769 opium injection, 760 Monsel's salt, 767 strychnia injection, 780 sulphate of quinia, 770 mercury, bichloride of, and zinc, 761 tannic acid solution, 779 turpentine and guaiacum, 313 injection of tea, 776 mixture of cubebs, 132 permanganate of potassa, 772 chronic, cubebs and ergot, 94 compound mixture of copaiba, 130 female, tannic acid pessary, 785 Gout, acid solution of veratria, 73 Becquerel's pill, 45 colchicum, colocynth, and mor- phia, 44 colchicum and laudanum, 83 glycerole of phosphorus, 335 Lartigue's pill, 48 magnesia and colchicum, 71 paregoric and guaiacum, 329 phosphate of ammonia, 573 phosphorated oil, 334 of stomach, ammonia and ginger, 320 INDEX OF DISEASES AND THEIR REMEDIES. 369 Gout— Scudamore's mixture, 72 Granular uterus, collodion of iodine and tannin, 285 HEADACHE, nervous, valerian and ammonia, 319 Hectic fever, diluted nitric acid, 581 Hematemesis, calomel and sugar of lead, 394 Hematuria, gallic acid pills, 603 Hemicrania, valerianate of quinia, 316 Hemoptysis, atomized fluid, 259 ergot and cinnamon, 613 opium and sugar of lead, 595 Hemorrhoids, confection of senna, sul- phur, and nitre, 60 copper, lead, and copal varnish, 932 electuary of jalap, nitre, etc., 61 suppository of opium and rhatany, 388 opium, tannic acid, and lead, 933 tannic acid suppository, 631 tar aud opium, 913 Hemorrhage, calomel and sugar of lead, 594 creasote mixture, 616, 617 matico infusion, 604 Monsel's solution, 623 perchloride of iron, 622 passive, alum, catechu, and opium, 596 oxide of silver and aromatic powder, 586 uterine, acetate of lead, enema, 630 Hepatic torpor, arsenic, podophyllin, and iron, 492 aloes, blue pill, and quinia, 537 calomel, 535 calomel and ox gall, 545 blue pill, rhubarb, and soda, 40 Harrowgate water, 583 nitro-muriatic acid, 580 Hepatitis, mercurial ointment and opium, 688 Herpes, anti-herpetic ointment, 897 chlorine, 832 creasote liniment, 834 cyanide of mercury, 893 Hydrothorax, colchicum and digitalis, 122 digitalis, calomel, and opium, 99 elaterium and colchicum, 121 Hysteria, assafoetida and ammonia, 331 assafoetida and soap pills, 407 assafoetida, valerian, and castor, 415 24 Hysteria — ammoniated iron, 473 assafoetida enema, 418 assafoetida and camphor, 413 sumbul and valerian, 412 Bestucheffe's tincture and valerian, 529 castor and succinic acid, 408 camphor, assafoetida, etc., 360 Hoffman's anodyne and laudanum, 414 valerianate of ammonia, 322 TMPACTION of the ear, cajeput oil, 1 742 Impetigo, arsenic and hemlock, 542 iodide of arsenic, 885 Impotency, cantharides, camphor, and opium, 312 Incontinence of urine, morphia and ve- ratria, 930 Indigestion, podophyllin, aloes, and iron, 478 Inflammation, poultice of bread and milk, 942 internal, caustics, epispastics, ru- befacients, 650-707 ipecac ointment, 922 emollient poultices, 948, 949 mush poultice, 944 Influenza, bloodroot and wild cherry, 216 boneset infusion, 1 72 sal-ammoniac, 572 Insomnia, camphor and Hoffman's ano- dyne, 368 Hoffman's anodyne and laudanum, 414 lactucarium and hemlock, 350 lupulin, 348 opium and henbane, 352 Internal irritations, discutient plaster, 936 mustard fomentations, 966 Intestinal irritations, barley water, 971 Iritis, atropia solution, 392, 393 belladonna mixture, 391 Irritation, bronchial, conium and Do- ver's powder, 185 LARYNGITIS, atomized fluids, 259 Croton oil and amber, 700 chronic, arsenical inhalation, 254 Spitta's lozenges, 194 Lead colic, opium and colocynth, 253 Lepra, arsenic and hemlock, 512 Asiatic pills, 541 370 INDEX OF DISEASES AND THEIR REMEDIES. Lepra — calomel and tar, 923 fumigation of sulphur, mercury, and iodine, 968 iodide of arsenic, 885 Leucorrhoea, cubebs and ergot, 94 tannic acid pessary, 785 Lichen, cyanide of potassium, 831 Lithiasis, powder of uva ursi, etc., 133 hydrangea arborescens, 138 oxalic, nitro-hydrochloric acid mix- ture, 140 iron and hydrochloric acid, 141 phosphatic, benzoic acid mixture, 119 mixture of muriatic acid, 142 mixture of phosphoric acid, 143 uric, acetates of potassa and am- monia, 124 injection of lithia, 146 injection of soda, 145 mixture of carbonate of mag- nesia, etc., 139 pills of carbonate of soda, etc., 134 solution of bicarbonate of soda, 136 soluHon of potassa, etc., 135 Lochia, fetid, permanganate of potassa, 781 Lumbrici, calomel and pinkroot, 287 electuary of cowhage, 301 electuary of tin, 300 iron lozenges, 295 male fern, 293 oil ofwormseed, 303, 304 pinkroot, savine, and senna, 288 pinkroot, senna, and santonin, 305 pinkroot and -worm-tea, 297 podophyllin, santonin, andiron, 291 salt and cochineal, 289 santonin, 290, 292 wormseed and rhubarb, 302 1TALARIAL disease, arsenic and iron, M 528 Mammary abscess, belladonna and bit- ter almond, 403 Menorrhagia, compound alum powder, 585 ergot and cinnamon, 613 ergotine, 275 oil of erigeron, 272 oxide of silver, 489 oxide of silver and aromatic pow- der, 586 phosphoric acid and opium, 267 VTAUSEA, bismuth, 466 1M clove plaster, 687 columbo, salt of tartar, etc., 646 calomel and bismuth, 15 creasote mixture, 616, 617 creasote and bismuth, 25 chloroform and soda, 23 lime-water and milk, 642 mustard, pepper, and ginger cata- plasm, 685 mixture of salt of tartar, 640 spice plaster, 686 nitrate of silver, 481 syrup of lime, 643 strychnia and bismuth, 17 morphia and sulphuric acid, 22 cardiac, prussic acid and morphia, 21 nervous, brandy and chloroform, 20 of pregnancy, ammonia, magnesia, etc., 645 cerium, nux vomica, and iron, 19 oxalate of cerium, 18 creasote, 315 pyroxylic spirit, 24 Nephritic colic, oil of turpentine, 118 turpentine and ether, 144 Nephritis, soda and uva ursi, 93 flaxseed tea, 973 Nervous atony, bromide of iron, 544 bromine, 562 cinchona and valerian, 515 depression, assafcetida and ammo- nia, 331 camphor and Hoffman's ano- dyne, 368 chloric ether, 374 musk and camphor, 409 valerianate of ammonia, 321 Neuralgia, arsenic and iron, 528 atropia lotion, 399 belladonna and bitter almond wa- ter, 403 bitter almond, 384 compound anodyne pill, 356 camphor and chloroform liniment, 404 opium and belladonna lotion, 398 opium and belladonna plaster, 402 opium and camphor plaster, 401 valerianate of zinc, 410 veratria ointment, 929 cranial, cinchona and valerian, 505 citrate of iron and quinia, 474 Vallet's mass and quinia, 476 vinegar draught, 513 facial, compound opiate liniment, 850 INDEX OF DISEASES AND THEIR REMEDIES. 371 Neuralgia, facial — cyanide of potassium and chlo- roform, 900 sal-ammoniac, 572 dental, anesthetic lotion, 396 thoracic, compound opium liniment, 851 ophthalmic, opium and camphor, 728 Night-sweats, gallic acid and morphia, 625 Nipples, sore, borax and glycerin, 856 opium and lime-water, 395 oxide of silver ointment, 926 tannate of lead, 935 tannic acid and glycerin, 866 OBSTRUCTION of bowels, opium and colocynth, 353 Odontalgia, Blake's drops, 794 creasote solution, 618 tincture of cayenne, 691 Ophthalmia, lapis divinus, 711 acute, acetate of zinc, 717 alum curd, 718 camphor and acetate of am- monia, 732 nitrate of silver, 719 opium and acetate of ammo- nia, 733 poppy and camphor collyrium, 736 quince seed, 729 chronic, alum collyrium, 712 atropia and tannin, 726 bichloride of mercury and quince seed, 730 borax and opium, 722 gallic acid and opium, 724 green vitriol, 714 Guthrie's ointment, 739 lead and opium, 715 vinegar and alcohol, 716 gonorrhceal, bichloride of mercury, 727 neonatorum, Bates' camphor water, 731 purulent, camphor and sulphate of copper, 721 rheumatic, wine of opium, 737 strumous, bichloride of mercury, 727 conia collyrium, 738 iodine solution, 703 iodine and iodide of potassium, 713 Lugol's ointment, 879 mercury and zinc, 741 Otitis, acute, tartar emetic ointment 690 Otorrhcea, aqua sappharina, 745 Bates' alum water, 744 catechu injection, 750 creasote injection, 752 lead and rose water, 743 sulphate of cadmium, 753 nitrate of silver, 746, 747 purulent, pyroligneous acid. 749 strumous, sulphite of soda, 748 Oxaluria, iron and hydrochloric acid, 141 mixture of nitro-hydrochloric acid, 140 Ozena, hyposulphite of soda, 756 iodide of zinc and permanganate of potassa, 755 mercurial inhalation, 255 permanganate of potassa, 754 PAIN, chloroform emulsion, 380 chloroform and cardamom, 379 chlorodyne, 376, 377 chloric ether, 374 laudanum, 362 laudanum enema, 385 sulphate of morphia, 349 morphia, sulphate of, 349, 364, 365 opium, 363 opium pills, 347 opium suppository, 386, 387 Paralysis, cantharides and camphor, 838 dux vomica, 359 nux vomica liniment, 848 phosphorus, 332 strychnia mixture, 372 of tongue, pellitory and mastich, 430 Pelvic cancer, conium suppository, 390 Pertussis, assafcetida mixture, 223 amber liniment, 843 atomized fluids, 259 bicarbonate of soda, etc., 219 bromide of ammonium, 220 conium, tolu, and paregoric, 211 cochineal mixture, 221 copaiba and tolu, 228 cimicifuga, 417 cloves and amber liniment, 847 bloodroot and naphtha, 224 lobelia, squill, and belladonna, 222 musk mixture, 411 nitric acid mixture, 416 sulphate of zinc and myrrh, 184 syrup of assafcetida, 199, 200 tartar emetic and laudanum, 218 372 INDEX OF DISEASES AND THEIR REMEDIES. Pharyngitis, brandy gargle, 788 rhatany gargle, 798 sal-ammoniac and acetic acid, 802 volatile liniment, 701 pomegranate and alum, 796 acute, alum, sage, and honey, 812 sage and flaxseed, 787 chronic, muriatic acid and cin- chona, 799 oak bark and alum, 789 pomegranate and chlorate of potassa, 797 quinia gargle, 790 sulphuric acid, 800 syphilitic, mel JEgyptiacum, 807 mercurial gargle, 801 ulcerated, iodine and opium, 808 Photophobia, opium and camphor, 728 Phosphatic lithiasis, benzoic acid mix- ture, 119 muriatic acid mixture. 142 Phthisis, atomized fluids, 259 ammoniac and nitric acid, 232 almond emulsion and ipecac, 212 Griffith's myrrh mixture, 507 inhalation of cubebs and carbolic acid, 258 infusion of wild cherry, 496 cyanide of potassium, 238 tar and hops, 246 morphia, squills, and tolu, 242 tolu, morphia, and tartar emetic, 243 morphia, glycerine, and iodide of iron, 244 prussic acid mixture, 237 perchloride of iron and nitric acid, 526 protoxide of iron, 508 squill, morphia, and prussic acid, 207 sulphate of zinc and alum, 11 oil of tar, 231 syrup of lactucarium, 205 syrup of the hyposulphites of lime, etc., 245 naphtha and morphia, 225 raw beef preparation, 1005 wild cherry and prussic acid, 201 Pityriasis, sulphuret of potassium, 825 Placenta, retained, Labarraque's solu- tion, 783 Pleurisy, aconite and acetate of am- monia, 170 acute, antimony, calomel, and Do- ver's powder, 187 Pneumonia, bloodroot and naphtha, 224 croton oil and amber, 700 morphia and turpentine, 241 Pneumonia — acute, antimony, calomel, and Do- ver's powder, 187 Poison, mineral, decoction of galls, 610 rattlesnake, Bibron's antidote, 563 Porrigo, depilatory ointment, 928 depilatory powder, 940 Pregnancy, acidity of, chloroform and soda, 23 albuminuria of, benzoic acid mix- ture, 120 potassa in milk, 111 constipation of, senna and prunes, 80 nausea of, cerium, nux vomica, and iron, 19 oxalate of cerium, 18 creasote, 315 pyroxylic spirit, 24 Prolapsus ani, suppository of opium and rhatany, 388 Pruritus vulvae, borax and morphia lo- tion, 868 Ptyalism, acetate of lead, 803 borax and myrrh, 791 disinfecting mouth-wash, 805 sulphate of zinc, etc., 793 Pyrosis, charcoal, magnesia, and gin- ger, 637 kino and opium, 600 magnesia and Colombo, 636 oxide of silver, 489 salt of tartar and ammonia, 641 strychnia and bismuth, 17, 493 RENAL atony, peracetate of iron, 525 Rheumatism, aconite and acetate of ammonia, 170 Rheumatism, aconite and colchicum, 169 burdock decoction, 176 camphor and chloroform liniment, 404 camphorated oil, 836 chloroform and aconite liniment, 406 chloroform and soap liniment, 405 gelsemium, 168 Harrowgate bath, 961 lemonade, 981 morphia and glycerin lotion, 863 propylamine, 369, 370, 371 Stokes' liniment, 837 stramonium in milk, 397 acute, compound powder of guaia- cum, 155 cannabis, 383 colchicum and cream of tartar, 96 INDEX OF DISEASES AND THEIR REMEDIES. 373 Rheumatism, acute — colchicum and laudanum, 83 guiiacum, nitre, etc., 165 magnesia and colchicum, 71 Scudamore's mixture, 72 chronic, aconite and Dover's pow- der, 361 buchu and iodide of potas- sium, 180 iodide and bromide of potas- sium, 567 Lartigue's pill, 48 phosphate of ammonia, 573 phosphorated oil, 334 SARCOMATOUS tumors, rhubarb and ipecac, 938 Scabies, aromatic sulphur ointment, 918 chlorine, 832 chlorine fumigation, 970 compound sulphur ointment, 896 corrosive sublimate, 828 Hebi-a's liniment, 845 iodide of sulphur, 884 naphthaline ointment, 919 sulphur ointment, 898 sulphuretted soap liniment, 846 white precipitate, sulphur, etc., 895 Scalds, see Burns. Scarlatina, belladonna, 373 Cayenne pepper gargle, 806 maligna, Cayenne pepper and salt, 338 Scrofula, Lugol's solution, 553 preparations of iodine, 548 ethereal tincture of iodine, 549 mixture of iodine, 551 iodine waters, 559, 560 iodide of iron, 552 iodide of potassium and sarsapa- rilla, 550 iron and chloride of barium, 179 Skin diseases, arseniate of soda, 570 arsenic and hemlock, 542 arseniate of iron, 540 alkaline bath, 959 Donovan's solution, 561 iodide of sulphur, 884 ethereal tincture of iodine, 549 iodide of iron ointment, 883 iodine and calomel, 886 Lugol's and Fowler's solution, 566 sulphuret of potassium, 849 hyposulphite of soda, 582 sulphureo-gelatinous bath, 955 sulphur bath, 954 emollient bath, 956 Harrowgate water, 583 Skin diseases — lead-water and glycerin, 864 sulphur and cream of tartar, 34 powders of sulphuret of antimony, etc., 153 sarsaparilla decoction, 178 serpentaria and red sulphuret of mercury, 174 tobacco fomentation, 967 Plummer's pill, 175 mezereon decoction, 177 chronic, cyanide of potassium, 831 strumous, iodine, 833 Spasm, camphor and opium, 354 Spinal irritation, veratria ointment, 929 Sprains, British oil, 844 camphor, amber, etc., 839 camphor and acetic acid, 840 compound chloroform liniment, 853 opium and lead, 852 origanum, camphor, etc., 855 petroleum, camphor, etc., 854 saponaceous fomentation, 963 Stomatitis, aphthous, borax and honey, 792 scorbutic, muriatic acid, 813 ulcerative, chloride of lime, 804 Strangury, liquor potassa in milk, 111 from blisters, parsley infusion, 107 Strumous disease, ioduretted baths, 960 swellings, bromide of potassium, 906 poultice of salt, etc., 952 Syphilides, buchu and iodide of potas- sium, 180 burdock decoction, 176 corrosive sublimate bath, 958 dilute nitric acid, 581 Donovan's solution, 561 iodine and mercury, 558 iodide and bromide of potassium, 567 mercurial vapor bath, 969 mezereon decoction, 177 nitro-muriatic acid bath, 957 Plummer's pill, 175 sarsaparilla beer, 181 sarsaparilla decoction, 178 Syphilis, blue mass, 426 bichloride of mercury and conium, 422 calomel, camphor, and opium, 425 corrosive sublimate, 579 cyanide of mercury, 428 Dupuytren's pills, 421 Falk's antacrid mixture, 584 mixture of iodine, 551 iodide of mercury, 423, 424 iodide of potassium, 555 374 INDEX OF DISEASES AND THEIR REMEDIES Syphilis — iodide of potassium and sarsapa- rilla, 550 iodo-hydrargyrate of potassa, 556, 557 oxide of mercury, 427 constitutional, bichloride of mer- cury, 420 Syphilitic disease, corrosive sublimate, 539 red iodide of mercury, 538 growths, sanguinaria, 941 nodes, iodine ointment, 876 pain, conium and calomel, 358 ulcers, iodide of mercury, 889, 890 mercury with opium, 894 TAPEWORM, calomel and gamboge, 286 emulsion of pumpkin seed, 308 kameela, 294 kousso, 299 mixture of male fern, 306 pomegranate root, 298 oil of turpentine, 307 Venice turpentine, calomel, etc., 296 Tinea capitis, alum, calomel, etc., 902 chlorine, 832 oil of cade, 914 sulphuret of potassium and lime- water, 826 tar and citrine ointment, 909 Tinnitus aurium, arnica, 336 Tonsillitis, volatile liniment, 841 acute, sage and flaxseed, 787 chronic, iodide of zinc, 809 Torpor of liver, blue pill, rhubarb, and soda, 40 Tuberculosis, cod-liver oil, 574, 575, 576 cod-liver oil and iodine, 578 cod-liver oil and quinia, 577 infusion of acorns, 506 iodide of potassium and manga- nese, 483 Tumors, glandular, ammonia and tartar emetic, 842 Tympanites, turpentine liniment, 696 ULCERS, chronic, chloride of zinc, 823 Goulard's extract and cam- phor, 821, 822 Ulcers, chronic — phosphoric acid, 827 exuberant, ointment of verdigris, etc., 921 savin and verdigris, 939 indolent, lead and calomel, 907 olive ointment, 912 red precipitate ointment, 875 carbonate of ammonia oint- ment, 920 rhubarb and opium, 908 verdigris and calomel, 937 irritable, spermaceti ointment, 874 strumous, iodide of potassium and opium, 892 iodine poultice, 953 phagedenic, antiseptic poultice, 950 black wash, 830 carbolic acid and castor oil, 925 charcoal poultice, 946 creasote lotion, 835 lime-water and zinc, 814 permanganate of potassa, 819 yellow wash, 829 syphilitic, aromatic wine, 870 Goulard's extract and cam- phor, 822 mercurial cerate, 899 iodide of mercury, 889, 890 Urethritis, chronic, buchu and uva ursi, 126 copaiba and cubebs, 100 Uric lithiasis, acetates of potassa and ammonia, 124 carbonate of magnesia, etc., 139 pills of carbonate of soda, etc., 134 solution of bicarbonate of soda, 136 solution of potassa, etc., 135 injection of lithia, 146 injection of soda, 145 Urine, incontinence of, cantharides and spirits of nitre, 117 Uterus, rigidity of, belladonna ointment, 901 TTAGINITIS, chronic, alum and catechu V pessary, 786 Vomiting, laudanum enema, 385 WOUNDS, contused, carbolic acid and castor oil, 925 Wounds of the eye, corrosive sublimate and opium, 734 STILLE'S THERAPEUTICS— New Edition— Now Ready. THERAPEUTICS AND~MATERIA MEDICA: A SYSTEMATIC TREATISE OX THE ACTION AND USES OF MEDICINAL AGENTS, INCLUDING THEIR DESCRIPTION AND HISTORY. By ALFRED STILLfi, M. D., Professor of the Theory and Practice of Medicine in the University of Pennsylvania. THIRD EDITION, REVISED AND ENLARGED. In two large and handsome octavo volumes of about 1700 pages ; extra cloth, $10 ; leather, $12. That two large editions of a work of such magnitude should - be exhausted in a few years, is sufficient evidence that it has supplied a want generally felt by the profession, and the unanimous commendation bestowed upon it by the medical press, abroad as well as at home, shows that the author has successfully accomplished his object in presenting to the profession a systematic trea- tise suited to the wants of the practising physician. Notwithstanding its enlargement, the pre- sent edition has been kept at the former very moderate price. From the Preface to the Third Edition. Although the second edition of this work had for many months been out of print, the author preferred to delay a new issue of it, rather than omit anything which appeared to be substantially valuable among the recent advances of the science and art of Therapeutics. The subjects now treated of for the first time are: Chromic Acid; Permanganate of Potassa; The Sdlphites of Soda, etc. ; Carbolic Acid ; Nitrous Oxide ; Rhigolene ; and Calabar Bean. The article on Bromine has been prepared entirely anew; and that on Electricity very materially enlarged by an account of the most recent improvements in electrical apparatus, and in the appli- cation of this agent to the cure of disease. The additions which have been mentioned, with much new matter besides, which will be found under the more important titles, occupy nearly one hundred pages. April, 1S6S. Dr. Still^'s splendid work on Therapeutics and Ma- teria Medica. — London Med. Times and Gaz., April S, 1865. He makes use of all these materials -with a skill and discrimination which must give his work a classical position among the text books prepared for American students. . . . Being under the necessity of criticizing it as though it were a French treatise on Therapeutics, our highest expression of praise is to record our re- gret that it is not among the manuals used in our own schools. . . . Dr. Still6's book deserves to be classed among the best and most practical treatises on Thera- peutics. — Translated from the Archives Generates de Iftdecine, Juin, 1860. PEREIRA'S MATERIA MEDICA. By WOOD.— Just Issued. MANUAL OF MATERIA MEDICA AND THERAPEUTICS; Being an Abridgment of the late Dr. Pereira's Elements of Materia Medica, arranged in conformity with the British Pharmacopoeia, and adapted to the use of Medical Practitioners, Chemists and Druggists, Medical and Pharmaceutical Students, etc. By F. J. FARRE, Senior Physician to St. Bartholomew's Hospital, and London Editor ok the British Pharmacopoeia; assisted by RO- BERT BENTLEY, M.R. C. S., Professor of Materia Medica and Botany to the Pharmaceutical Society of Great Britain; and by ROBERT WARING, F. R. S. ; Chemical Operator to the Society of Apothecaries. Edited, with numerous references to the United States Pharmacopoeia, and many other Additions, By HORATIO C WOOD, Jr., M D , Professor of Botany in the University of Pennsylvania. In one large and handsome octavo volume of 1030 closely printed pages, with, 236 illustrations. Extra cloth, $7 ; leather, raised bands, $8. llustrations, some of which are original. We The reader cannot fail to he impressed, at a glance, with the exceeding value of this work as a compend of nearly all useful knowledge on the materia medica. We are greatly indebted to Professor Wood for his adaptation of it to our meridian. Without his emen- dations and additions it would lose much of its value to the American student. With them it is an Ameri- can hook. — Pacific Medical and Surgical Journal, December, 1S66. Altogether the work is a most valuable addition to the literature of this subject, and will be of great use to the practitioner of medicine and medical student. The work, as issued by the American publisher, is a handsome volume of 1030 pages, most amply illus- trated, the wood-cuts being of superior finish, and clearly impressed. — Canada Med. Jnurn., Nov. 1S66. The task of the American editor has evidently been no sinecure, for not only has he given to us all that is contained in the abridgment useful for our purposes, but by a careful and judicious embodiment of over a hundred new remedies has increased the size of the former work fully one-third, besides adding many unhesitatingly say that by so doing he has propor- tionately increased the value, not only of the con- densed edition, but has extended the applicability of the great original, and has placed his medical coun- trymen under lasting obligations to him. The Ameri- can physician now ha> all that is needed in the shape of a complete treatise on materia medica, and the medical student has a text-book which, for practical utility and intrinsic worth, stands unparalleled. Al- though of considerable size, it is none too large for the purposes for which it has been intended, and every medical man should, in justice to himself, spare a place for it upon his book-shelf, resting assured that the more he consults it the better he will be satisfied of its excellence. — N. Y. Med. Record, Nov. 15, 1866. We have here presented, in a volume of a thousand pages, that which we sincerely believe the best work on materia medica in the English language. No phy- sician, no medical student, can purchase this hook, and make anything like a proper use of it, without being amply rewarded for his outlay. — T lie Cincin- nati Journal of Medicine, November, LS66, HENRY C. LEA-Pliiladelpliia. PARRISH'S PHARMACY— Third Edition. A TREATISE ON PHARMACY. DESIGNED AS A Text-book for the Student, and as a Guide for the Physician and Pharmaceutist. WITH MANY FORMULAE AND PRESCRIPTIONS. BY EDWARD PAEEISH, Professor of Materia Medica in the Philadelphia College of Pharmacy, &c. Third Edition, greatly Improved. In one handsome 8vo. volume of 850 pages, with several hundred illustrations,- extra cloth, $5. The thoroughness with which the very complete plan of this work has been carried out may be estimated by the fact that the Index contains about 4700 items. Under the head of Acids there are 312 references ; under Emplastrum, 36 ; Extracts, 159 ; Lozenges, 25 ; Mixtures, 55 ; Pills, 56 ; Syrups, 131 ; Tinctures, 138; Unguentum, 57 ; &c. &c. It thus becomes a storehouse of pharmaceutical knowledge, to which the physician can at all times refer with the certainty of finding the latest practical information on all subjects coming within its scope. compelled to give the above work only a book notice. It was onr wish and intention to attempt an extended analysis of its contents, that our readers might jud*e somewhat for themselves of its great and numerous merits, but the subject-matter is of such a nature as to forbid anything like a review. All that we can say of it is, that to the practising physician, and es- pecially the country physician, who is generally his own apothecary, there is hardly any book that might not better be dispensed with. It is at the same time a dispensatory and a pharmacy. — Louisville Review. Of course, all apothecaries who have not already a copy of the first edition will procure one of this; it is, therefore, to physicians residing in the country and in small towns, who cannot avail themselves of the skill of an educated pharmaceutist, that we would especially commend this work. In it they will find all that they desire to know, and should know, but very little of which they do really know in inference to this important collateral branch of their profession ; for it is a well-established fact, that, in the education of physicians, while the science of medicine is gene- rally well taught, very little attention is paid to the art of preparing them for use, and we know not how this defect can be so well remedied as by procuring and consulting Dr. Parrish's excellent work. — St. Louis Med. Journal. In this connection, the very able work of Edward Parrish on " Practical Pharmacy," deserves most honorable mention, supplying as it does a real want, and in the most satisfactory manner. The profession has long needed a work which should contain the leading facts and principles of the science arranged for study, and with special reference to those features of the subject which possess a practical interest to the physician. Although medicines are mostly sup- plied to the profession ready prepared, yet there are thousands of practitioners in the United States to whom pharmacy is necessarily a collateral pursuit ; to many of these, and to the numerous students under their charge, an elementary work designed as an introduction to pharmacy has long been a desidera- tum. This want no longer remains unsupplied. — Report on Med. Literature, Trans. Am. Med. Assoc, 1S66. We know of no work on the subject which would be more indispensable to the physician or student desiring information on the subject of which it treats. With Griffith's "Medical Formulary" and this, the practising physician would be supplied with nearly or quite all the most useful information on the sub- ject. — Charleston Med. Journal and Review. It is with reluctance and much regret that we are A UNIVERSAL FORMULARY, Containing the methods of Preparing and Administering Officinal and other Medicines, THE WHOLE ADAPTED TO PHYSICIANS AND PHARMACEUTISTS. BYEOBEET E. GRIFFITH, M. D., &c. SECOND EDITION, THOROUGHLY REVISED, WITH NUMEROUS ADDITIONS, BYEOBERT P. THOMAS, M. D., Professor of Materia Medica in the Philadelphia College of Pharmacy. In one large and handsome 8vo. vol. of over 600 pages, double columns, extra cloth, $4- 00 ; leather, $5 00. It was a work requiring much perseverance, and wheu published was looked upon as by far the best work of its kind that had issued from the American press, being free of much of the trashy, and embrac- ing most of the non-officinal formula used or known in American, Euglish, or French Practice, arranged under the heads of the several constituent drugs, plac- ing the receipt under its more important constituent. Prof. Thomas has certainly "improved," as well as added to this formulary, and has rendered it addition- ally deserving of the confidence of pharmaceutists and physicians.— American Journal of Pharmacy. We are happy to announce a new and improved edition of this, one of the most valuable and useful works that have emanated from an American pen. It would do credit to any country, and will be found of daily usefulness to practitioners of medicine ; it is better adapted to their purposes than the dispensato- ries. — Soutliern Med. and Surg. Journal. A new edition of this well-known work, edited by R. P. Thomas, M, D., affords occasion for renewing our commendation of so useful a hand-book, which ought to be universally studied by medical men of every class, and made use of by way of reference by office pupils, as a standard authority. It has been much enlarged, and now condenses a vast amount of needful and necessary knowledge in small compass. The more of such books the better for the profession and the public— N. Y. Med. Gazette. It is one of the most useful books a country practi- tioner can possibly have in his possession. — Medical Chronicle. The amount of useful, every-day matter, for a prac- tising physician, is really immense. — Boston Med. and Surg. Journal. This is a work of .six hundred and fifty one pages, embraciug all on the subject of preparing and ad- ministering medicines that can be desired by the phy- sician and pharmaceutist. — Western Lancet. In short, it is a full and complete work of the kind, and should be in the hands of every physician and apothecary. — O. Med. and Surg. Journal. We predict a great sale for this work, and we espe- cially recommeud it to all medical teachers.— Rich- mond Stethoscope. This edition of Dr. Griffith's work has been greatly improved by the revision and ample additions of Dr. Thomas, and is now, we believe, one of the most complete works of its kind in any language. The additions amount to about seventy pages, and no effort has been spared to include in them all the re- cent improvements which have been published in medical journals and systematic treatises. A work of this kind appears to us indispensable to the physi- cian, and there is none we can more cordially recom- mend.— 2V. J. Journal of Medicine. HENRY C. LEA, Philadelphia. ^■LLi^K *- _ <^< - ; ^JW U«c c , c^ssrx^r ~ cc •-cc : " « «rcxc« ST c c 4 C3§^ec; L^C«CjC :. CS ^C * «zc