wKiraSS: IBSTO KiSSffi sSUgg HHH Iffil ISiiP 888 ttttMOT SSuSffi jjlfflffiw l!i.ra;; : gS$j& «&&§£ Mffiffi SSffiB K98H BgHJgjB afflg 'i' '•'• • • mSm JrJjEt 1 *^ 1 ** $5g>8wcS5$ m^fxti:.--: m msassm BSBBbNB m SB n ■■1 ■ ■* 9 oSmffi ^^H ■ bhBB w iff iso*a Class. Book.. :&£ Copyist ft .- COFVRIGHT DEPOSifc FENNER'S COMPLETE FORMULARY L7I Sixth Edition of Fenner's Formula?-)*, greatly enlarged, _ revised and entirely re-written. WORKING FORMULAS FOR ALL Offk i\i. am) Unofficial Preparations Generally Used ok Required in the Practice of Pharmacy and the rlrsy- ness of the Chemist, Manufacturing Pharma- cist, Manufacturer of Proprietary Med- icine, Physician, Perfumer, Etc. A COMPLETE FORMULARY AND HAND-BOOK Of Valuable Information for Pharmacists, Manufacturers of Chemical and Pharmaceutical Preparations, Physicians. and Students of Pharmacy and Modicine. ^*~ —» AUG 27IH08 Wpiled and written by \ B. R E N N E l? Bv B. FENNER. BUFF A tO , N . Matthews, Nqrthrup & Co., Akt- Office of the "Buffalo Morning PREFACE. TI 7HEN, in 1874, the first edition of Fenner's Formulary (then a small pamphlet) was issued it was the pioneer in a new field of pharmacy, and furnished the first reliable line of formulas for elixirs and the so-called Elegant Preparations which were then coming rapidly into use. Several editions of this work, each much enlarged and improved, have suc- ceeded each other ; but all have been, necessarily, crude and imperfect, repre- senting, as they did, the developing stage of the art of Elegant Pharmacy. Such as they were, however, they have been received, and adopted by the mass of American Pharmacists as the standard authority for the preparation of this class of galenicals. During the past decade the advance of Pharmacy and the introduction of new drugs, chemicals and forms of medicine has been so great, that it has outrun the text-books extant, and there has grown up a great want and demand for a new and complete work which shall represent the Pharmacy of to-day as it is practiced throughout the land. The Pharmacopoeias and works of authority are all too conservative — representing only a small part of the preparations used. The Dispensatories and other commentaries on the Pharmacopoeias partake of the same general characteristics ; while the Pharmaceutical Journals ( which are the main repositories of unofficial formulas, the record of new preparations and of the advance of Pharmacy ) lack the continuity and unity of purpose which is necessary to the value of books of reference and practical works on Pharmacy. What druggists want, and demand, is a work that in one volume shall give reliable formulas for all or most of the preparations required in the polyphar- macy of the present day, and in which they are certain to find, at a glance, some practical information on all subjects connected with or pertaining to the practice of their profession. To make such a work requires patient research and ' investigation, extended and repeated experiments, careful analyses and syntheses; a thorough knowledge of the wants, conveniences and capabilities of pharmacists, and of the practice of pharmacy as it is in all parts of the country; an intimate acquaintance with the standard text- 3 PREFACE. books and pharmaceutical literature of all countries; and, last but not least, the ability to collate, compare, condense, classify and arrange, and the genius and experience necessary to originate and formulate, preparations useful to those engaged in the trade. Realizing the requirements of such a work, as well as its necessity, and knowing the great amount of time and labor necessary to produce it, the author, with great reluctance, and only after repeated solicitation from a great number of those who were using the former editions of Fenner's For- mulary, undertook the preparation of this volume. To embody in one book whatever is valuable to druggists of pharmacy, chemistry, materia medica, therapeutics and formula; has been his aim and purpose. How far it may fulfill that purpose, those who use it will decide. The former editions of this work have been chiefly devoted to the Elegant Preparations, such as elixirs, fine syrups, medicinal wines, etc., but it was deemed expedient in this edition to include the official preparations as well, and whatever else was necessary to make, as its title indicates, A Complete Formulary, to which those in search of information may turn, avoiding the trouble and annoyance of looking through so many books of reference before finding what they seek. Many new and, as we think, valuable processes have been introduced, which are the outcome of long experience in the preparation of medicines, and as such are submitted. We have endeavored to make a volume simple, practical, comprehensive, and plain — an every-day companion, counsellor and friend. It has been written mainly in the workshop or laboratory in the midst of the drugs and operations which it describes or directs. As such, no claim is made for its literary excellence, but it is earnestly hoped that it may contribute something of value to the practice and science of pharmacy, and something of pleasure and profit to Pharmacists into whose hands it may fall. Westfield, N. Y., August, 1888. CONTENTS. INTRODUCTORY. General Plan of the Work, 9 Weight and Measure Standards, ic Heat Measures • 12 Specific Weight or Gravity, 14 PART I. DRUGS AND MEDICINAL SUBSTANCES. Mineral Drugs 17 I Vegetable Drugs, 19 Elementary Chemical Substances, 18 1 Animal Drugs, 23 PART II. WORKING PROCESSES. Dialysis, Distillation Evaporation Expression Filtration Fineness of Powder, .... 31 Infusion and Decoction, ... 33 Maceration 33 Percolation, 34 Water-Bath Percolation, . . 40 Solution, 44 Washing Precipitates, ... 44 PART III. WORKING FORM1 1. 1 Abstracta — Abstracts, ... 46 Aceta — Acetates — Vinegars, 50 Acida — Acids 55 .1. tin-res — Ethers, .... 77 Etheroles or Etherates, . . . 80 Albumen 83 Alcolioles — Alcohols, ... 84 Aldehydes — Aldehyds. ... 96 Alkalies 97 Alkaloides — Alkaloids. ... 98 Ally) Aloe— Aloes Aluminium Ammonium Amyl 150 Amylum — Starches 152 '34 135 r.16 [41 CONTENTS. Anilina — Anilines, .... 154 Antimonium — Antimony, . . 155 Aqua? — Waters, 161 Argentum — Silver 172 Arsenicum — Arsenic, . . . 177 Aurum — Gold 179 Balsama— Balsams, .... 180 Barium 187 Benzinum — Benzin 189 Benzolum — Benzene — Benzol, 189 Bismuthum — Bismuth, . . . 191 Boron 197 Bromum — Bromine 200 Butyl or Tetryl 201 Cadmium 203 Caesium 204 Calcium 204 Carbonium- — Carbon, . . . 210 Cera- — Waxes, . . . ■. . 214 Cerata — Cerates 217 Cerium, 225 Cetaceum —Spermaceti, . . 226 Charta? — Papers, 227 Chemicals 232 Chloral 233 Chlorine 235 Chloroforum — Chloroform, . 237 Chocolata — Chocolate — Cocoa, 237 Chromium 238 Cobaltum — Cobalt, .... 240 Collodia — Collodions, . . . 240 Colores — Colors, 244 Confectiones — Confections — Conserves 255 Cordiales — Cordials, .... 261 Creasotum — Creasote, . . . 263 Cuprum — Copper, .... 264 Cyanogen 267 Decocta— Decoctions, . . . 267 Destillata? — Distillates, . . . 270 Dextrinum — Dextrin, . . . 271 Dialysatae — Dialysates, . . . 272 Diastase 273 Elaterium 274 Elixiria — Elixirs 274 Emplastra — Plasters, . . 382 Emulsiones — Emulsions, . . 394 Essentia? — Essences — Flavor- ing Extracts 408 Ethyl, 440 Extracta — Extracts 441 Extracta Destillata — Distilled Extracts 451 Extracta Fluida — Fluid Ex- tracts 453 Fel Bovis — Ox-Gall 497 Fermentum — Yeast 498 Ferrum — Iron 498 Fluorine, 513 Gelatina — Gelatin, ... 513 Glucose and Grape Sugar, . . 515 Glycerinum — Glycerin, . . . 516 Glycerita — Glycerites, . . . 517 Glycyrrhizinum Ammoniatum, 523 Hydrargyrum — Mercury, . . 523 Hydrogenium — Hydrogen, . . 532 Infusa — Infusions, .... 533 Iodoformum — Iodoform, . . 539 Iodum — Iodine 540 Lac — Milk 541 Lamella? — Discs, 542 Linimenta — Liniments, . . . 543 Liquores — Solutions, . . . 546 Lithium 592 Lotiones — Lotions 596 Magnesium, 598 Maltum — Malt, 603 Manganese, 613 Massae — Masses 616 Mellita — Honeys 618 Methyl 619 Mistura? — Mixtures, .... 620 Mucilagines — Mucilages, . . 630 Niccolum — Nickel, .... 633 Nitrogenium — Nitrogen, . . 634 Olea — Oils, 636 Oleata — Oleates, 655 Oleoresina? — Oleo-resins, . . 660 Opium 664 Oxygenium — Oxygen, . . . 666 Pancreatinum — Pancreatin, . 667 Pepsinum — Pepsin 668 CONTENTS. Peptones, 670 Petroleum, 671 Petrolatum 672 Phenyl 672 Phosphorus, 673 Picrotoxinum — Picrotoxin, . . 675 Piluke — Pills, 675 Pix — Pitch 694 Platinum 695 Plumbum — Lead, 695 Potassium or Kalium, . . . 699 Propyl or Trityl, 713 Pulveres — Powders 713 Pyroxylinum — Gun Cotton, . 721 Resins — Resins 722 Resinoids or Concentrations, . 731 Sacchara — Sugars 733 Salicinum — Salicin, .... 736 Salicyl 736 Santoninum — Santonin, . . 737 Sapoes — Soaps 738 Selenium, 745 Silicon 745 Sodium or Natrium 746 Species — Teas 758 Spiritus — Spirits, 759 Stannum — Tin 773 Strontium, 774 Succi — Juices, 775 Sulphur, 778 Suppositoria — Suppositories, . 782 Syrupi — Syrups, 790 Tabellae — Tablets, .... 871 Tannin or Tannic Acid, . . . 873 Tellurium, 874 Thallium, 874 Theriaca, 874 Tinctora — Dyes 875 Tincturae — Tinctures, . . . 880 Tisanes, 956 Triturationes — Triturations, . 956 Trochisci — Troches, .... 956 Tungsten or Wolframium, . . 967 Unguenta — Ointments, . . . 967 Uranium 994 Urea, 994 Vanadium, 995 Vanillin 995 Vapores — Vapors 995 Vina — Wines 997 Zincum — Zinc 1015 PART IV. I III. STANDARD REMEDIES AND PROPRIETARY MEDICINES. Acid Phosphate 1023 Ague Cures 1023 Alteratives, 1026 Anodynes, 1027 Asthma Remedies 1029 Balms or Panaceas [03] Balsams 1033 Bitters 1036 Blood Purifiers, 1044 Carminatives 1045 ! Catarrh Remedies 1047 Cathartics and Laxatives. . . 1049 Cholera Cures 1053 Condition Powders 1055 Corn, Bunion and Chilblain Cures 1059 Cough Remedies 1061 Diarrhoea and I ) ysentery Reme- dies, 1068 Dyspepsia Cures, 1070 Elixirs, Essences and Extracts, 1073 Eye Waters 1075 Eye Salves, 1075 Female Remedies 1076 Hair Dyes, Restoratives and Tonics 1079 Heart Preparations 1084 Hypophosphites Compound, . 1085 8 CONTENTS. Inhalants and Inhalers, . . . 1085 Injections 1086 Iodide Alteratives, 1087 Kidney and Liver Remedies, . 1089 Liniments, 1092 Nervines, Hypnotics and Seda- tives, 1098 Ointments and Salves, . . .1102 Pectorals 1106 Pills, Plasters and Powders, . 11 07 Rheumatic Remedies, . . .1108 Sarsaparilla Compounds, . . iiio Soothing and Teething Syrups, 1 1 13 Salts or Saline Aperients, . .1115 Specifics 11 17 Tonics 1 1 18 Tooth Ache Remedies, . . .1120 Worm Medicines, 1122 Unclassified Proprietary Rem- edies 1 1 26 PART V. TOILET PREPARATIONS AND PERFUMES. Bandolines, 1131 Cosmetics for the Complexion, 11 32 Dentifrices n 36 Hair Preparations 11 40 Cosmetic Ices and Jellies, . .1146 Lotions for the Complexion, . 1148 Lip Salves and Cosmetics, . . 11 49 Nail Cosmetics, 1 1 50 Perfumes for the Handkerchief, 1 1 50 Odors of Flowers, 1 1 54 Colognes and Toilet Waters, .1156 Sachet Powders, 1 1 59 Smelling Salts and Pungents, . 11 60 Toilet Soaps, 1 16 1 Toilet Vinegars, 1161 Toilet Waters 1 162 PART VI. MISCELLANEOUS FORMUL.E. Adhesive Preparations ( Ce- ments, Glues, Mucilages, Pastes, etc.) Baking Powder, Cloth Cleaning Compounds, . Exterminators, Destroyers and Poisons, 1 163 1 167 1 168 Foods, Prepared 1171 Inks, Bluings and Blackings, . 1172 Polishing Preparations, . . .1180 Preservatives, 11 S3 Wines and Spiritous Liquors, . 11 84 Varnishes, 11 92 1 1 70 Unclassified Preparations, '95 INTRODUCTORY. IN the arrangement of the formulas in this volume the plan of numbering them has, as in former editions, been adopted. This method saves fre- quent repetition of the formulas, makes them convenient for reference, and at the same time more particularly designates one from another, as there are in many instances several preparations bearing the same name yet differing in composition. The official preparations are designated by their Latin titles as given in the Pharmacopoeias ; but few others are thus distinguished, as they are generally called for or prescribed by their more common names. Prominence is also given to most of the official and to the elegant preparations by printing them in larger type than those of less importance. Whenever a material difference exists in the formulas official in the U. S. P. and those of the Br., German, French, or other leading pharmacopoeias, the composition of the preparation as directed by the different authorities is given. Also, when there is any important difference between the U. S. 1880 and 1870 pharmacopoeia preparations, the same is noted in the formula. In the formulas copied from other works, when the original text is followed. the source from which they are derived is usually mentioned ; but when for- mulas are collated from various sources, and re-arranged, re-written, or re- adjusted to suit the plan of this work, their authority is not generally given, as they are, mostly, public property, having become such by long usage and frequent publication in standard works. In conformity with the popular usage in this country the quantities directed in the formulas are mostly in the commercial weight and measure of the U. S. The attempts to introduce metric weight and measure or parts by weight of solids and liquids have not met with a favorable reception in this country, although generally used in Continental Europe. In the article on weights and measures which follows, directions will be found for readily converting weights or measures of one system into those of another. As this work is intended mainly as a formulary, the description of pharma- ceutical apparatus in general use, and the description of medicinal substances, except as given under general headings, is mostly omitted ; for the same rea- son, the tests of chemicals, etc., are not generally given. A brief general description of crude medicinal substances will be found in Tart I., ami the general working processes employed in pharmacy are brielly described in PART [I. For further descriptions, tests, etc., reference may be made to the pharmacopoeias, chemistries and other technical works. The medicinal use 9 10 INTRODUCTORY and doses of most preparations are briefly given under their formulas, for convenient reference. The formulas are, as far as is practicable, arranged in classes. The offic- ial formulas and those employed in regular pharmacy are included in Part III., and are classed according to their pharmaceutical similarity, as elixirs, extracts, fluid extracts, spirits, syrups, etc. Chemical elements and radi- cals are noted in their alphabetical order, their salts and combinations being included under the same general headings — as Sodium and its salts, Potas- sium and its salts, etc. Standard proprietary remedies are included in Part IV., and classed according to their medicinal properties, uses, etc. — as Ague Cures, Catarrh Remedies, Cough Remedies, etc. Toilet articles and perfumes are given in Part V., and are arranged as far as possible according to their uses as Hair Preparations, Handkerchief Perfumes, Lotions, etc. Miscellaneous Preparations, in which are included those not otherwise classified, make up Part VI., and are arranged as far as possible according to their uses. WEIGHTS AND MEASURES STANDARDS. The United States Pharmacopoeia previous to the 1880 revision and all standard American text-books directed troy weight and apothecary measure. The present revision of the United States Pharmacopoeia directs metric weight and measure whenever definite weight and measure is mentioned, but parts by weight are generally directed. The British Pharmacopoeia and text-books direct avoirdupois weight and equivalent fluid measure. All of the Pharmacopoeias of continental Europe direct parts by weight, or metric weight and measure. The Grain is the equivalent unit of the apothecary, troy and avoirdupois systems of weight. Apothecary and troy weight correspond, the terms of the former only being used by druggists. The Scruple equals 20 grains. It is now seldom used, being expressed in grains instead. The Drachm equals 60 grains or >s apothecary or troy ounce. The Ounce of apothecary or troy weight equals 480 grains or 1-12 of the apothecary or troy pound of 5,760 grains. The Ounce avoirdupois weight ( American commercial and British phar- maceutical standard) equals 437^ grains or 1-16 of the avoirdupois pound of 7,000 grains. The Pound of apothecary or troy weight equals 5.760 grains or 12 apothe- cary or troy ounces of 480 grains. The Pound avoirdupois weight ( American commercial and British phar- maceutical standard ) equals 7,000 grains or 16 avoirdupois ounces of 437/4 grains. The Gramme is the unit of metric weight. A gramme equals 10 deci- grammes or 100 centigrammes or 1,000 milligrammes or 15-43 grains. WEIGHT AND MEASURE STANDARDS. 11 The Kilogramme equals iooo grammes or 35.27 av. ounces, and is equiv- alent to the litre. A Cubic Centimetre of water at 4' C. ( 39/ F. ) weighs a gramme ; there- fore the gramme and cubic centimetre are equivalent. It equals 16^ minims. The Litre is the unit of metric fluid measure, and equals 1,000 cubic centi- metres, or 10 decilitres or 100 centiliters or 33.84 Am. fl.ounces. The Minim is a variable expression of fluid measure — the 480th part of a fluid ounce. The minim of American fluid measure of water at its greatest density weighs about 0.95 grain, being the 480th part of the American fluid ounce of 455.7 grains of water. The British minim being the 480th part of the British fluid ounce of 437^ grains of water — weighs about 0.91 grain. The Fluid Drachm equals 60 minims or y% fluid ounce. The American Fluid Drachm of water weighs 56.96 grains, being l /i of the American fluid ounce of 455.7 grains of water. The British Fluid Drachm of water weighs 54.68 grains, being y% of the British fluid ounce of 437 >< grains of water. The Fluid Ounce equals 480 minims or 8 fluid drachms. The American Fluid Ounce of water weighs 455.7 grains, and is 1-16 of the American pint of 7,291.1 grains of water. The British Fluid Ounce of water weighs 437 }i grains, and therefore corresponds with their weight standard ( avoirdupois ) ounce, it is 1-20 of the British Imperial pint. The Pint of American fluid measure (28.875 cllD i c inches) equals 7,680 American minims; 7,291.1 grains of water or 16 fluid ounces of 455.7 grains of water, at 60 F. The Imperial Pint of British fluid measure (34.659 cubic inches ) equals 9,600 British minims ; 8,750 grains ( 1 % pounds avoirdupois ) of water or 20 British fluid ounces of 437^ grains of water at 60" F. The Gallon of American fluid measure (231 cubic inches) equals 61,440 American minims ; 58,328.9 grains of water or 8 American pints. I he Imperial Gallon of British fluid measure (277.274 cubic inches) equals 76,800 British minims ; 70,000 grains ( 10 pounds avoirdupois) of water or 8 Imperial pints, The relation of weight to fluid measure as above stated is calculated for distilled water at 15.6 C. (60 F. )• The volume of water increases or decreases in a ratio varying with the temperature. At 1 5.6 C. (6o° F.) its volume is 1.000938, as compared with 1.000000, its volume at its greatest density 4 C. 1 39 F. ). To convert the which is of one system into those of another, the following simple rules may be observed : To convert Troy to Avoirdupois. — Multiply the weight in tr.ounces by 1.097 for close, or by 1.1 for ordinary calculations. The product is the weight in av.ounces. Avoirdupois to Troy. -Multiply the weight in av.OUnces by 0.9H for close, or deduct one tenth for ordinary calculations. The product, or is the weight in tr.OUl 12 INTRODUCTORY Metric to Grains. — Multiply the weight in grammes by 15.43. Metric to Troy Ounces. — Multiply the weight in grammes by 0.032. Metric to Avoirdupois Ounces. — Multiply the weight in grammes by 0.035. In ordinary calculations, 28 v, grammes are considered equal to 1 ounce. Grains to Grammes. — Multiply the weight in grains by 2, and divide by 13. The quotient is the weight in grammes. Troy to Metric. — Multiply the weight in tr.ounces by 31.1. The product is the weight in metric grammes. Avoirdupois to Metric. — Multiply the weight in avoirdupois ounces by 28.35. The product is the weight in metric grammes. To convert the measures of one system into those of another, the follow- ing simple rules may be observed : To convert Apothecary to Imperial Fluid Measure. — Multiply the measure in apothe- cary (1. ounces by 1.041. The product is the measure in Imperial flounces. Imperial to Apothecary Fluid Measure. — -Multiply the measure in Imper- ial fl.ounces by 0.96. The product is the measure in apothecary fl.ounces. Metric to Apothecary Fluid Measure. — Multiply the measure in cubic centimetres by 16X to reduce to minims, or by 0.034 to reduce to fl.ounces. The litre equals about 2 pints, 1 y& Am. fl.ounces. Metric to Imperial Fluid Measure. — Multiply the measure in cubic centi- meters by 0.035 to reduce to Imperial fl.ounces. Apothecary to Metric Fluid Measure. — Multiply the .measure in fl.ounces D >' -9-53- The product is the measure in cubic centimeters. In ordinary calculations 30 cubic centimeters equal 1 fl. ounce. Imperial to Metric Fluid Measure. — Multiply the measure in fl.ounces by 28.35. The product is the measure in cubic centimeters. HEAT MEASURES. The only scales now used to any extent for registering temperature are those of Fahrenheit, Reaumur, and Celsius ; the latter being known in most countries as the Centigrade scale. The Fahrenheit scale is chiefly used in America and Great Britain, the Reaumur in Germany, and the Centigrade in France and other countries of Europe, and in scientific calculations in nearly all countries. Thermometric scales are calculated from the expansion of mercury or alco- hol in a small vacuum tube having usually a bulb or reservoir at the bottom. The CENTIGRADE scale assumes the temperature at which water freezes as o , and the temperature at which it boils with the barometer at 30 inches, as ioo , making ioo : between the freezing and boiling point of water. The Fahrenheit scale assumes the temperature at which water freezes as 32 , and the temperature at which it boils with the barometer at 30 inches, as 212 , making 180 between the freezing and boiling point of water. The Reaumur scale, which is seldom used in this country, assumes the temperature at which water freezes as o°, and the temperature at which it HEAT MEASURES. 13 boils with the barometer at 30 inches, as 8o D , making 80" between the freez- ing and boiling point of water. The following table shows a comparison of the scales from the freezing to the boiling point of water : C. F. R. Water 100 212 So boils. 95 203 76 90 194 72 S5 185 6S So 176 64 75 167 60 70 158 56 65 149 52 60 140 48 55 I3i H 50 122 .... ... 40 45 "3 36 40 104 32 35 95 2S 30 86 24 25 ........ 77 20 20 68 16 15 59 12 5 41 4 Water o 32 o freezes. It will be seen by the foregoing scales that a Centigrade degree is r| Fah- renheit, or t Reaumur degrees ; that a Fahrenheit degree is f Centigrade, or % Reaumur degrees ; and that a Reaumur degree is iX Centigrade, or 2)4 Fahrenheit degrees. The following rules will be found convenient for reducing or converting one scale to another : To reduce Centigrade to Fahrenheit. Rule. — Multiply the given degrees Centigrade by \\ (?), and add 32 to the product. EXAMPLE. — How many Fahrenheit degrees in 25 Centigrade degrees? 2 5 j +■ 32—77 Fahrenheit degrees. To reduce Reaumur to Fahrenheit. RULE. — Multiply the given degrees Reaumur by 2% and add 32 to (lie product. To reduce Fahrenheit to Centigrade. RULE.-- Subtract 32 from the given degrees Fahrenheit and divide the remainder by 1 J (|). EXAMPLE.— How many Centigrade degrees in 176 Fahrenheit degrees? 176 — 32-Hj— 80 Centigrade degrees. To reduce Fahrenheit to Reaumur. RULE. — Subtract 32 from the given degrees Fahrenheit and divide the remainder by 2/4 1 \), To reduce Reaumur to Centigrade. Ri 1. 1.. - Multiply the given degrees Reaumur by \%. 14 INTRODUCTORY. 0.80 R. 0.44 R. 1.25 C. = F . degrees. To reduce Centigrade to Reaumur. Rule. — Multiply t 'lie given degrees Centigrade by \. In reducing Fahrenheit to other scales, or vice -versa, 32 is added or sub- tracted, because the Fahrenheit scale is marked 32 where the other scales are marked o, viz., at the freezing point of water. Bear in mind that in comput- ing degrees below o c Centigrade, or Reaumur, the product of the multiplica- tion is a minus quantity, and that adding +32 to the minus quantity is the same as taking the difference between them. Recent American works on Pharmacy and Chemistry give both the Centigrade and Fahrenheit degrees, so there is no reason that the druggist should not soon be as familiar with the one as the other. The temperature at which the specific gravity of substances is usually taken and recorded, is 15.6° Centigrade, or 60 Fahrenheit, or 12.4° Reau- mur. In making experiments or calculations that require accuracy, this must be well understood, and the substances to be used must be brought to this temperature. SUMMARY. i C. = i. So F. = ! 1 F. = 0.55 C. = 1 R. = 2.25 F. = C. degrees X 9 -=- 5 + 32 C. " X 4 -*- 5 = R- F. " -32 X 5 ■+■ 9 = C. " F. " -32 X 4 ■+■ 9 = R- " R. " X 9 -*- 4 + 32 = F. R. " X 5 -*- 4 = C. A unit of heat is the amount of heat necessary to raise a certain quantity of water one degree. The French unit, called a caloric, is usually adopted. It is the amount of heat required to raise one kilo ( 2.204621 5 t1>s. avoirdupois) of water one degree centigrade; that is, from o toi C. SPECIFIC WEIGHT OR GRAVITY. Specific weight or gravity is the weight of a substance compared with the weight of an equal volume of some other substance taken as a standard. Distilled water at 15.6° C. ( 6o : F. ) is the standard with which all solids and liquids are compared to calculate their specific gravity. The specific gravity of water is expressed by unity, as 1, 1.00, 1.000, i.ooco, etc., substances heavier than water being more than a unit, lighter than water, less than a unit, expressed in decimals. Air or hydrogen at 15. 6° C. (6o : F. ), and the barometer at 30 inches, are the standards with which gases are compared to determine 'their specific gravity. As applied to pharmacy the specific gravities of solids and liquids only are required, therefore the processes for estimating their specific gravity, only, SPECIFIC WEIGHT OR GRAVITY. 15 will be considered in this- article. For the specific gravity of gases our readers are referred to the standard works on Chemistry. Few druggists are provided with delicate specific gravity apparatus, and indeed it is unnecessary that they should be, for a few simple articles, always at hand, will suffice for the druggists' purpose as well the most elaborate and costly apparatus. A thermometer, a thin bottle and accurate balances or scales are all the apparatus required for finding the specific gravity of liquids and solids, and druggists seldom need to determine the specific gravity of gases. The following are the simple directions for CALCULATING THE SPECIFIC GRAVITY OF LIQUIDS. First. — Take a thin bottle that will hold three or four ounces;* paste strips of paper on two opposite sides and weigh the bottle accurately, mark- ing the weight in grains,+ on one of the strips. Then weigh in the bottle just iooo grains of distilled water at a temperature of 15.6"" C. ( 6o : F. ) and mark the strips of paper on each side of the bottle just at the surface of the water, when the bottle is standing perfectly level. Mark iooo, the weight of the water, under the weight of the bottle and add them together for the gross weight, then empty the bottle and it is ready for use. Second. — Having brought the liquid to be calculated to the required tem- perature, 1 5. 6° C. (6o c F.), pour it into the bottle previously used, until its surface comes just level with the water-level marks on the strips of paper ; then weigh it accurately, noting the gross weight in grains. Third. — Find the difference between 'the gross weight of the first and second operations. If the weight of the first operation is greater than the second, subtract the difference from iooo and point off three places as deci- mals. If the weight of the first operation is less than the second, add the difference to 1000 and point off three places as decimals. Example i. The gross weight of a bottle with iooo grains of water is 1723 grains; the gross weight of the same volume of a liquid in the same bottle is 1 67 1 grains. What is the specific gravity of the liquid ? 1723 — 1671 = 52 difference. — 52 = 0.948 specific gravity of liquid. EXAMPLE 2. The gross weight of a bottle with iooo grains of water is 1723 grains ; the gross weight of the same volume of a liquid is 21 84 grains. What is the specific gravity of the liquid ~: I -1723 = 461 1 : 461 = i. 461 specific gravity of liquid. * A long-necked bottl.-. that toco grains of water will fill into the neck, is the most . Specific gravity bottles, made verj light and designed to hold 100 or 1000 grains, or 50, 250 or 500 grammes, may be obtain nical iri t Metric weight may be used instead of grains. Grains are mentioned American druggists are so much more familiar with this weight than with the metrii system. 16 INTRODUCTORY This method of determining the specific gravity of liquids is quite accurate, and very convenient when the bottle is once prepared. It is also adapted to small quantities of liquids as it can be calculated for ioo grains or 10 grains in the same general manner. It can be used also for light or heavy liquids, which is another convenience. The Hydrometer is an instrument used for determining the specific gravity of liquids. There are many kinds, but nearly all act on the same principle, viz. : The depth to which they sink in the liquid, which is shown by the graduated scale in the stem of the instrument. It is not accurate enough for fine work, and cannot be used for small quantities of liquids. The Hydrometer is principally useful for showing the proof of spirits, the degree of acids, syrups, etc., but is not adapted to the general work of calcu- lating specific gravity in the business of the pharmacist. The spirit Hydrometer will not answer for heavy liquids, nor the acid nor syrup Hydrometer for the light liquids. The Government Hydrometer for spirits which has the thermometer scale attached is of much value in estimating the proof of spirits. CALCULATING THE SPECIFIC GRAVITY OF SOLIDS. The druggist is so seldom required to calculate the specific gravity of solids, that mere mention, only, of the methods will be given here. Solids heavier than water are first weighed in the ordinary way, and then, by suspending them to one side of the balance by a fine thread, are immersed in water and weighed. The ordinary weight divided by the loss of weight in water gives the specific gravity of the solids. Solids lighter than water are first weighed, and then attached or tied to some heavy metal of known 'weight and specific gravity ; the two substances are then weighed and immersed in water together and the loss of weight of the lighter substance found by deducting the loss of weight of the heavy metal, previously found, from the total loss. The original weight of the lighter substance is then divided by its loss of weight in water, as shown by the former operation and the result is the specific gravity of the substance. Solids soluble in water are first weighed by the balance and then weighed suspended in some liquid in which they are insoluble, as Naphtha, Alcohol or Oil. The weight in the liquid subtracted from the ordinary weight gives the loss of weight ; the ordinary weight is divided by the loss of weight thus obtained, and the quotient multiplied by the specific gravity of the liquid in which the solid was weighed — this gives the specific gravity of the solid. Powdered substances are first weighed, and their weight added to that of the specific gravity bottle and iooo grains of water, as described for calculat- ing the specific gravity of liquids. The powder is then put in the bottle and enough distilled water at 15.6 C. (6o rj F.) added to fill it to the water-level marks on the bottle. It is then weighed and its weight subtracted from the gross weight previously obtained ; this shows the loss of weight in water. The ordinary weight of the powder is now divided by the toss of weight as shown by the subtraction ; the quotient is the specific gravity of the powder. PART I DRUGS AND MEDICINAL SUBSTANCES, The substances used in the art of pharmacy are obtained from every part of the known world, and are selected from all departments of the mineral, vegetable, and animal king- doms. The mineral kingdom contributes the greater portion, the vegetable a great variety, and the animal a fair percentage of the substances which are known in the commercial world as " Drugs." The collection and preparation of " drugs " for the market constitutes a very great industry, second in importance to none of the commercial industries of the world. In the limited space which we have to devote* to this subject, mere mention only of what is most important to druggists can be made, as its elaboration would, of itself, fill a volume. MINERAL DRUGS. Nearly every mineral known is, in some form, made use of in pharmacy. Minerals and mineral salts were the first sub- Stances employed in medicine. The science of chemistry owes irly advancement to the researches of the alchemists and apothecaries in mineral substances, and the legends of medii ine and pharmacy are mainly based upon the wonderful powers and qualities attributed to minerals. The collection of native mineral substances does not come within tin- province of pharmacy, and at present but few mineral salts arc prepared by pharmacists. That task", which 17 L8 DRUGS AND MEDICINAL SUBSTANCES. was formerly a necessary part of the education and business of the apothecary, now being given over to manufacturing chem- ists, who have better facilities and conveniences for doing it. In chemistry, all elementary mineral substances are called bases or radicals, from their property of combining with acids to form salts. The following table of elementary substances includes the minerals, which, with their various combinations and salts, comprise a large share of the so-called " chemicals " used in pharmacy. TABLE OF ELEMENTARY SUBSTANCES. U. S. P., 1SS0. iLT" Weight ELEMENTS. Syrn- Atomic bol. Weight. lent. Aluminium Al Antimony Sb Arsenic As Barium Ba Beryllium (Gluci- num) Be Bismuth Bi Boron B Bromine Br Cadmium Cd Caesium Cs Calcium Ca Carbon 1 C Cerium Ce Chlorine 2 CI Chromium Cr Cobalt Co Copper Cu Didymium Di Erbium E Fluorine Fl Gallium G Gold Au Hydrogen H Indium In Iodine I Iridium Ir Iron Fe Lanthanum La Lead Pb Lithium Li Magnesium Mg Manganese Mn Mercury | Hg 27 120 74-9 136.8 79.S iii.S 132,6 40 12 141 35-4 52.4 53-9 63.2 144.6 165.9 J 9 68.8 196.2 1 "3-4 126.6 192.7 55-9 138.5 206.5 7 24 54 199.7 13-5 120 74-9 6S.4 79.8 55-9 132.6 20 6 70.5 35-4 26.2 29-45 31.6 72.3 82.95 19 34-4 196.2 56.7 126.6 96.35 27-95 138.5 103.25 7 12 27 99-35 Molybdenum Nickel Niobium. . . . Nitrogen 3 . . . Osmium .... Oxygen 4 . . . . Palladium . . . Phosphorus . Platinum. . . . Potassium . . . Rhodium . . . Rubidium . . . Ruthenium. . Scandium. . . Selenium. . . . Silicon Silver Sodium Strontium. . . Sulphur 5 .. . . ! Tantalum. . . Tellurium . . I Thallium . . . Thorium. . . . Tin Titanium . . . Tungsten . . . Uranium . . . Vanadium . . Ytterbium. . . Ytterium.. . . Zinc Zirconium . . Mo Ni Nb N Os O Pd P Pt K Rh Rb Ru Sc Se Si Ag Na Sr S Ta Te Tl Th Sn Ti W U V Yb V Zn Zr 95-5 58 94 14 198.5 16 105.7 31 194-4 39 104. 1 85-3 104.2 44 78.8 28 107.7 23 87.4 32 1S2 12S 203.7 233 H7.7 48 183.6 238.5 51-3 172.7 42-75 29 94 14 99-25 8 52.85 3i 97.2 39 52.05 85-3 521 22 39-4 14 107.7 23 43-7 16 1S2 64 203.7 116.5 58.85 24 91.8 119-25 51-3 172.7 64.9 32.45 90 45 Carbon : 11.9736. 1 ( >xygen : 15.9633. - Chlorine : 35.370. 5 Sulphur: 31. Nitrogen: 14.021 DRUGS AXD MEDICINAL SUBSTANCES. 19 Inorganic Chemical Products. The process by which substances unite to form other sub- stances or compounds is called chemical action, and the force with which they so unite is called chemical attraction or affinity ; mineral chemical substances are called inorganic; vegetable and animal chemical substances are called organic. Inorganic Chemical products are produced by the union of mineral bases with acids, and the salts thus composed consti- tute a large share of the chemicals of pharmacy and commerce. The salts thus formed bear the names both of the base and acid of which they are composed ; for examples, acetate of potassium or potassium acetate, sulphate of iron or ferrous sulphate, bi-chloride of mercury or mercuric chloride, etc. The names of chemical salts are distinguished by certain prefixes or terminations, which indicate in a measure the pro- portions of the combinations. For a full understanding of these, and chemical nomenclature in general, the reader is referred to standard words of chemistry. VEGETABLE DRUGS. By far the greater number of substances used in medicine are of vegetable origin. Nearly every plant that grows has at one time or another played its part in the history of Pharmacy, and newly-discovered ones, with "wonderful virtues," are still being brought to light from " lands beyond the sea." Hut little attention is now given by Pharmacists to gathering and curing vegetable drugs ; that branch of the business, which was in former time an important part of the trade of the Apothecary, being given over to collectors and others who have better facilities for carrying it on. Vegetable substances are, or should be, gathered at the season when they contain the greatest amount of medicinal value, and are prepared for market in various ways, which depend largely upon the intel- ligence, experience and convenience of the collectors. A brief mention of crude vegetable drugs, and the methods 20 DRUCiS AND MEDICINAL SUBSTANCES. employed for preparing them for the market may not be superfluous. Balsams. — Main- substances of quite different consistence and composition are classed as Balsams. They are generally gathered by puncturing pustular cells in the bark, or by making cuts or incisions in the bark or wood of certain trees or plants. They are liquid, semi-solid or solid. Barks. — Barks are gathered in the early spring just after the sap has started to flow. The bark ma}' then be readily stripped from the branches, trunk or root, and it contains as much or more medicinal value than at any other season. The bark from twigs or small branches is easiest removed by heating them over a fire and then pounding them with a billet of wood. The trunk-bark of trees is generally removed in slabs or strips, the outer portion being shaved or hewed off and discarded, the inner bark only being used ; the root-bark has usually to be shaved off. Barks are dried in the open air or by moderate heat in kilns, evaporators, or other heating appa- ratus, and come into the market in the form of quills, small slabs, stripes, or broken in small pieces. They are then cut. crushed, ground, or powdered as desired for sale or use. Berries. — Under the common name of berries are included many of the smaller fruits, like strawberry, raspberry, etc.; the small fleshy fruits, like juniper, ash, and laurel, and the dry, un- ripe berries, like cubeb, spice, and pepper. The juices of some berries are used, while others are gathered and dried by suit- able heating apparatus, to prepare them for the market. Buds. — A few kinds of leaf-buds, like Balm of Gilead, are gathered, dried, and used in medicine ; but the term is usually used in Pharmacy to designate undeveloped flower-buds, of which cloves and cassie-buds are examples. They are gathered in their proper season, and dried in the open air for the market. Flowers. — Flowers should be gathered in their early blos- soming before they have passed their prime ; many, even, are best gathered when the buds are opening. They are usually gathered with as little of the stalk as possible, except in the case of plants and herbs, which are gathered entire at the season of DRUGS AND .MEDICINAL SUBSTANCES. 21 flowering. Flowers should be dried with as little exposure as possible, and packed away in a dry, cool place. Fruit. — Fruit is a botanical name for all kinds of vegetable- growths enclosing and including seeds ; but different kinds of fruit are classed and named according to their peculiarities : as fleshy fruits, of which apples and berries are examples, stone fruits, of which the peach and cherry are examples, and dry fruits, which include nuts, capsular and other dry fruits, seeds, etc. Fruits are generally gathered when the seeds are ripe, and are dried, preserved, or otherwise treated according to their nature and use. Fleshy and stone fruits should be dried in an evaporator or other suitable drying apparatus, while the dry fruits are either sufficiently dry when ripe, or maybe dried in the open air. Many of the fruits are classed commercially as berries, nuts, seeds, capsules, etc. Gums and Gum-Resins. — Among the natural vegetable substances which are collected and put upon the market, a certain class of gums and gum-resins may be included. They are the exudations from plants either from the stings of insects, or from incisions made for the purpose of collecting the gum or gum-resin. The collection of gums and their prepara- tion for the market forms a very large and important industry. Besides the gums and gum-resins, there are many substances known commercially as gums which are of an entirely different character — as opium, which is a concreted juice, and catechu, which is properly an extract. Herbs. — In pharmacy herbs are understood to be the upper portion of small plants, including the leaves, flowers and small stalks, the larger stalks and roots being discarded. ( onmiercially, the smaller plants, which are gathered entire, are also classed with herbs. Herbs should generally be gathered when in blossom, carefully dried without artificial heat, and packed away in a cool, dry place. Plants. Plants, as the term is understood botanically, include all vegetable-growths, great or small ; but in pharmacy the name is generally applied to small plants which are gathered and used entire. They should be gathered about the season of flowering, and dried without artificial heat. 22 DRUGS AND MEDICINAL SUBSTANCES. Leaves. — Leaves should be gathered when the plants or trees arc at their fullest prime. With plants, this is generally a little before the flowering season ; and with trees and shrubs, usually a little before the ripening of the fruit. Leaves should be dried without artificial heat and packed away in a cool, dry place. Nuts. — Nuts are properly classed with fruits. They are gathered when ripe, thoroughly dried and prepared in various ways for the market. Roots. — Commercially considered, roots are the parts of plants which grow in the ground; in pharmacy, however, they are divided into several classes according to their nature — as root, rhizome, rootlets, bulb, cormus, tuber, etc., the three latter not being properly classed with roots. Roots should generally be gathered after the leaves are off the plants in the fall, or before they start in the spring. The bark, only, of many woody roots is used, while some are gathered entire, being cut, sliced, crushed or otherwise prepared for market. The rhizome is the main portion of the root or rootstock, to which the root- lets, if any, are attached. Of the roots which consist of rhizome and rootlets, some are used entire, while others, only the rhizome or rootlets may be used. The bulb, cormus and tuber are classed with roots com- mercially, but are botanically dissimilar. Bulbs are usually sliced and dried ; cormus and tuber ma)- be sliced or dried whole. Seeds. — Many of the so-called " seeds," as caraway, carda- mom, coriander, fennel, etc., are classed in pharmacy as fruit. The botanical distinction being, that when two or more separate seeds are enclosed by a pericarp or envelope, the structure is called fruit, while the seed itself is a single ovule, containing the embryo and its nutriment. Seeds are generally gathered when ripe and dried if necessary by natural heat. Some of the fruits which are commercially classed as seeds require artificial heat. Woods. — The greater part of the woods used in the drug- business are for dyeing purposes. A few, however, are used as medicine. They are generally furnished to druggists in chips, or shavings, or ground to the proper fineness for use. DRUGS AXD .MEDICINAL SUBSTANCES. 23 Pharmaceutical and Chemical Products. The man}- products which are derived from vegetable sub- stances may conveniently be classed *as pharmaceutical and chemical. In the former class ma}- be included such as are generally prepared by pharmacists in their business, and in the latter, such as are usually prepared by the larger manu- facturing chemists. Of the former class, fluid extracts, solid extracts, tinctures, spirits, syrups, etc., and of the latter, the alkaloids and their salts, vegetable acids, alcohol and distilled spirits, etc., ma)- be mentioned. ANIMAL DRUGS. But few animal substances, comparatively, are used in medi- cine, yet in the aggregate the drugs derived from the animal kingdom form quite a percentage of the druggists' stock. In the early days of medicine, animal substances were used to a great extent — the most ridiculous and foolish use being- made of them — but, as the science of medicine has emerged from its early superstitions, they have been mostly dropped, and only such as are of known value retained. The fats and oils obtained from animal tissue constitute the greater portion of animal-matter used in pharmacy. Some ex- pensive animal substances, such as musk and ambergris are used quite extensively in perfumer)-. Pepsin, pancreatin, albumen, the meat extracts, etc., arc used internally. Cantharides is most used externally, and many other animal substances have various uses in medicine or pharmacy. Pharmaceutical and Chemical Products. The pharmaceutical products prepared from animal sub- stances are mainly the cerates, ointments and plasters, in which animal fats and wax arc used as bases. Several tinctures also are prepared from animal substances, such as cantharides, castor, musk, etc. The chemical products consist mainly of a few alkaloids and their salts, and may Include pepsin, pancreatin. etc., as they are not usually prepared except by manufacturing establishments. PART II. WORKING PROCESSES. The processes which are here noted are such as druggists do or may employ in their business, without expensive apparatus or special pharmaceutical education. Many other processes are employed by chemists and large manufacturers which it would be needless to detail here, as they would not be used by druggists generally. DIALYSIS. The process by which certain substances are separated from other substances with which they are combined in solution, by means of the diffusibility of liquids through a thin mem- brane, is called Dialysis. The physical principle, involved in this operation, is that of the diffusion of liquids, called endosmosis and exosmosis. Although this process is not officinal, it may be frequently employed to advantage in pharmacy, and it no doubt merits more consideration than it has hereto- fore received. In pharmacy, dialysis is employed to separate what are known as colloid (glue-like) substances, from their com- bination in solution with crystallizable substances. This is accomplished by means of an apparatus called a Dialyzer, imple form of which is here illustrated. This apparatus may be made by any druggist, without expense, and is sufficient for the requirements of most retail dealers. Larger apparatus maybe made on the same principle. 24 < SP# WORKING PROCESSES — DIALYSIS. 25 It consists of an ordinary white glass 7-inch lamp-shade, the bottom of which is covered over with parchment paper, which is large enough to extend up the sides of the shade nearly two inches, and which is held in place by two rubber bands. The solution to be dialysed is placed in the apparatus thus constructed, and floated on distilled water, contained in any convenient earthenware vessel. (An earthenware milk-pan which is shown in the cut, is convenient for this purpose, or an ordinary wash-bowl may be used.) The dialyzer may be suspended by a string from above, or set upon bottles in the earthenware vessel, so that the surface of the liquid in the dialyzer may be about on a level with the surface of the water in the vessel. Parchment paper for this purpose may be made by immersing firm, unsized paper in a mixture of two measures of Sulphuric Acid with one measure of water, and afterward washing it thoroughly with pure water to remove all traces of acid. It may also be bought, at a small price, of jobbers or dealers in pharmaceutical apparatus. Dialysis is applicable only to aqueous solutions, and the process is used sometimes to obtain the colloid, and sometimes the crystalloid, principles from their solutions. The colloid substances are always retained in the floating vessel or dialyzer, while the crystalloid substances are found in the water with which the dialysis is conducted. In working the process to obtain tin: colloid substances, the water in the vessel should be changed every day ; but in working it to obtain the crystal- loids, as little water as is necessary for the purpose should be used, for it has subsequently to be evaporated to obtain the crystallizable substance. Gum arabic is a familiar example of a colloid, and sugar, of a crystalloid substance. If they are both represented in a solution, the gum will be retained in the floating vessel, while the sugar will gradually be transferred to tin- water, in which it floats. In conducting the process of dialysis it should be continued so long as the water in the lower vessel contains appreciable traces of tin- soluble crystalloid, or other substance, which the process is designed to remove. Dialysed iron is probably the most familiar colloid preparation made by dialysis. WORKING PROCESSES — DISTILLATN >N. DISTILLATION. The process of vaporizing a liquid or other substance, by the aid of heat, and then condensing the vapor to a liquid by cold, in an apparatus called a still,* is known as Distillation. This process is used for separating liquids of a less from those of a greater specific gravity; for separating liquids from soluble substances which they hold in solution ; for separating volatile substances from grosser matter with which they are associated, and for purifying and freeing liquids from objec- tionable matter. As applied to pharmacy, distillation is employed for recov- ering alcohol from many preparations which are required to be concentrated by evaporation, such as fluid extracts, solid ex- tracts, etc., for distilling medicinal waters and spirits, for obtain- ing ethers, essential oils, etc., and for many other purposes. Although distillation is frequently directed in the Pharma- copoeia, no advice nor instructions are given in regard to it, it being assumed that druggists are sufficiently familiar with the * Fenner's Water-bath and Still is a convenient, simple apparatus for evaporating and distilling. It consists of a cylindrical, shallow vessel, A, into which is fitted the shallow evaporating pan, B (which serves as the vessel for open evaporation, and also for evaporation during distilla- tion) ; and the SECTIONAL VIEW. COIlical Still IlENNER,S Water -^ATH AND STILL. top, 6", in which the vapor, which rises, is condensed during the process of distillation. This apparatus is constructed specially for evaporating and distilling; it is low and shallow, having a large bottom surface, fitting it well for rapid evaporation and distillation. Fenner's Water-bath Percolator and Still may be employed for the same purposes, but as it is constructed for percolation also, corresponding sizes do not present so large a surface for evaporation and distillation as does the Water-bath and Still. Druggists will find it a great convenience to have the Water-bath and Still, as well as the Water-bath Percolator and Still, for they are often both required at the same time. WORKING PROCESSES — EVAPORATION. 27 process to enable them to conduct it properly. A few sugges- tions, however, may not here be amiss. To distill medicated waters or other aqueous substances no water-bath is required, the distillation of such liquids being more rapid, and equally as satisfactory, without it. If herbs, leaves, flowers, seeds or other similar substances are to be distilled, they should be protected from contact with the bottom of the still by a false bottom, so that they may not "scorch," and sufficient water should be used with them to prevent the extract which collects at the bottom from " burn- ing down." At least, double the quantity of water that is taken of the drug should be used. To obtain oils from medicinal plants, seeds, etc., the most approved method is to pass a current of steam through the herbs, or other substances, by which the particles of oil are vaporized and carried over with the steam and condensed, being afterwards gathered from the surface of the water. To distill or recover Alcohol or any substance of less specific gravity than water, the liquid should be placed in the water-bath and the heat communicated to it, by heating the water surrounding it. The boiling point of the alcohol or other lighter liquid being lower than the boiling point of water, it is vaporized and condensed in the still ; the heavier liquids and extractive matter remaining in the water-bath. When drugs are percolated with alcohol, or a partly alco- holic menstruum, the menstruum remaining in the drug can be recovered by transferring the moist drug to the water-bath of the still and distilling in the usual manner. If the water-bath percolator and still is used, it is unnecessary to transfer the drug, as the still top can be adjusted, heat applied, and the distillation completed without further trouble. The process of distillation is a very important and economical one in pharmacy, and is much less employed than it should be. EVAPORATION. As applied to pharmacy, evaporation is the process by which, with tin: aid of heat, the volume <>!' liquids or other substance may he reduced. It is employed for many purposes 28 W< >RKING PR( >( ESSES — EVAPORATION. in the practice of pharmacy, and is so familiar to druggists, that but little need be said regarding it in this article. The vessels used for evaporating should be broad and low, or shallow, to give a larger surface for the application of heat and the escape of vapor. Evaporating dishes are made of glass, iron (enameled or glazed), platinum, porcelain, tin, etc. Heat is applied in various ways for the purpose of evapo- rating — by the ordinary methods, by water-bath, sand-bath, steam, heated air, etc. For rapid evaporation, heat over an open fire or by means of steam is best ; but for making many preparations, such as extracts, fluid extracts, etc., slower evaporation is necessary, that the preparation may not be injured by the heat. For this purpose the water-bath* is the most convenient for drug- gists' use, as by it the heat can be regulated and maintained at any desired temperature. In large establishments the vacuum pan, which is still better for the purpose, is employed. This consists of a large pan and chamber covering it, from which the air is removed by means of an air-pump, causing the liquid in the pan to evaporate at a much lower temperature than in the open air. The most serviceable, cheap, evaporating dish, is the ordi- nal'}- granite-iron stove skillet, or frying-pan. Any ordinary evaporating dish may be set in a vessel of water, which wall answer as a water-bath. A sand-bath may be made by partly filling an iron basin with sand and setting the evaporating dish in it. For very slow evaporation a warming closet may be made, by fastening a box against the wall and heating it with a lamp placed underneath a hole in the bottom ; smaller holes should also be provided in the upper surface for the escape of vapor. This box can be so arranged with shelves that a number of evaporating dishes may be placed in it at the same time. *The water-bath which forms a part of Fenner's Water-Bath axd Still is very convenient for the purpose of evaporation. It is shown in the sectional view on page 26 by the vessels A and B. Fenner's Water- Bath PERCOLATOR (see page 41 ) may also be used for the same purpose, it being necessary only to put the liquid to be evaporated into the percolator and leave off the cover. EXPRESSION — FILTRATION. EXPRESSION. The process of expression is employed more or less for many uses in pharmacy, the apparatus and manner of working being governed by what is required to be done. In making tinctures, fluid extracts, etc., a considerable quantity of menstruum is left in the drug after the percolation is completed, and it is economy to recover it by pressure in a tincture press or other suitable apparatus ; pressure is also employed as the chief operation in some processes for making fluid extracts (see Fluid Extracts). In choosing a tincture press for any purpose, it is not economy to get the smallest sizes, a one- or two-gallon press being none too large for most pharmaceutical work. The drugs to be expressed should be inclosed in a coarse burlap bag or cloth, and the pressure should be long continued rather than too quick and forcible, that the liquid may have time to become separated from the drugs. In pressing pulpy or mucilaginous drugs it is an advantage to mix them with some loose non-absorbing material, rice chaff, for example, to facilitate the operation. Fruit juices, in a small way, are best expressed by hand pres- sure, except such fruits as lemon, orange, etc., which can be pressed with a lemon squeezer. In a large way, fruit may be pressed in large wooden presses, the layer presses being the best variety for this purpose. In using small presses nothing is gained by trying to press too much at a time, the operation being more satisfactory in moderate quantities. There are several good kinds of presses to be had for phar- maceutical purposes, the " Enterprise " being as convenient and serviceable as any. There are several so-called " pressure percolators" now sold, but, in our opinion, they arc not con- venient percolators, and they certainly fail to do the work of a press. FILTRATION. The process of separating insoluble matter from liquids, by means <>f any substance or medium which will prevent iis passage, is called filtration. 30 WORKING PROCESSES — FILTRATION. Filtration, as it is employed in pharmacy, is usually conducted by means of filtering paper contained in a conical receptacle called a funnel ;* but larger operations are carried on by other contrivances which will admit of a more rapid filtration. The process of filtration is so familiar that it needs no explanation ; but a few suggestions are here made for the benefit of the inexperienced. In filtering a liquid which contains a precipitate (unless the precipitate is designed to clear the liquid, as magnesia or pumice-stone are used) the liquid should be poured carefully off and filtered first, the precipitated portion being added after most of the liquid has passed through the filter; this makes the process more rapid. The first portion that passes through the filter should be returned to it and re-filtered, as, when the filter is dry, it admits of the passage of small particles which are retained when its fibers have had time to swell by the absorption of moisture. In filtering liquids containing albuminous or gummy pre- cipitates, it is also advantageous to put a coarse cotton cloth strainer on the inside of the filter paper ; this catches the pre- cipitate or albuminous substance, which may be removed with it, or in which it may be pressed to strain out the liquid, and thus make the filtration more rapid. * Fenner's Spiral Filter Rack is a convenience for keeping the filtering paper off the sides of the funnel when filtering. It is made of tinned steel wire, of different sizes to fit different size funnels. It is simple, cleanly, durable, efficient and cheap. The cut shows it as it is adjusted in the funnel ready for use. Heat often assists the process of filtering heavy liquids or oils. It may be conveniently applied by putting a filter inside of Fenner's water-bath percolator, and applying heat by means of the water-bath. For supporting the funnel during filtration, Fenner's Funnel Rack, which is shown in the cut, is very con- venient. Further remarks on filtering will be found in the article on " Economy in Percolating and Filtering," page 39. FINENESS OF POWDER. 31 A plaited filter is generally used, except when a filter-rack is employed, then the ordinary folded (quartered) filter is used. Besides filtering through paper, other means are often employed by druggists. Syrups and heavy liquids may be filtered through a flannel or cotton strainer, or felt filters that are made expressly for this purpose. Charcoal and sand, in alternate layers, are employed for filtering light liquids when larger quantities are to be filtered. A little charcoal in powder, or powdered pumice-stone sprinkled in the filter, will often assist to clear preparations that are difficult to filter clear. FINENESS OF POWDER. To properly obtain the soluble constituents of drugs by the process of percolation, they should be so comminuted or divided that the menstruum may readily dissolve all soluble matter. To this end, different drugs are directed to be reduced to different degrees of fineness as experience has shown to be best suited to their nature. The United States Pharmacopoeia has adopted the following standard for the fineness of powders: ( should pass through a \ A very fine powder - sieve having 80 or more \ equals No. 80 powder. ( meshes to the linear inch, ) ( should pass through a ) A fine powder - sieve having 60 meshes to > equals No. 60 powder. ( the linear inch, ) , , . . . 1 should pass through a ) A moderately fine \ . , \ f / , „ - sieve having 50 meshes to V equals No. ;o powder. pow.hr ; .' s ? ' - ' f the linear inch, ) A moderately coarse should pass through a J - sieve having 40 meshes to r equals No. 40 powder. ( the linear inch, ) 1 should pass through a ) / oarse powder - sieve having 20 meshes to V equals No. 20 powder. ( the linear inch, ) Other degrees of fineness than ■ the foregoing are often directed. 32 FINENESS OF POWDER. It is desirable for the purpose of percolation that the pow- der used should be as uniform as possible, it is therefore directed in the Pharmacopoeia that " not more than a small proportion of the powder should be able to pass through a sieve having ten meshes or more to the linear inch." While this direction is valuable for securing a uniform powder and there- by promoting the process of percolation, it is, in our opinion, unwise to specify this limit ; for in reducing drugs to different fineness of powder by any process which druggists may com- mand, it is obvious that, unless the powder is very fine, quite a proportion of it will be much finer than the coarsest powder which will pass through the sieve having the required number of meshes to the inch. If this portion is separated from the coarser powder by sifting, that which remains will not truly represent the entire substance of the drug from which it was prepared. In preparing a powder, therefore, for percolation the entire quantity of drug which is taken should be reduced to a powder that will pass through a sieve having the required number of meshes ; or, if this produces a powder too fine for successful percolation, a coarser sieve should be used ; for it is better to use a coarser powder than to remove any portion of the drug which would be represented by the finer powder. For the reasons stated the powders directed in the formula? of the U. S. P., are, as a rule, too fine for successful percolation by the majority of druggists, and better results will be secured by using about one grade coarser powder than is designated. Drugs are usually reduced to the required degree of fineness for percolation by grinding in a drug mill, but when finer pow- ders are required the old, time-honored mortar and pestle comes into play. But few druggists, however, attempt to make what are known in the market as " powdered drugs." They are usually bought of reliable houses who make a business of putting them up. Drugs "ground for percolation " may also be bought in the market, but as the}- always come in bulk without the guarantee of a reliable house, they are liable to adulteration, or to be ground from old or worthless drugs, and it is much better for the druggist to grind them himself, as needed, from reliable crude drugs. INFUSION AND DECOCTION — MACERATION. 33 INFUSION AND DECOCTION. The process of INFUSION consists in steeping drugs at a temperature below the boiling point of water, in an aqueous or other menstruum, for the purpose of extracting their solu- ble medicinal constituents. For this purpose, "infusion pots," which contain a perforated cup or receptacle for the drug, which is surrounded by hot water during the operation, are furnished by manufacturers of chemical ware. A covered granite-ware, or earthen-ware, vessel will answer the same purpose ; the Avater-bath percolator is however the best adapted of any apparatus for the purpose of infusion, as the heat can be maintained and the liquid drawn off by the stop- cock whenever it is desired. For making infusions, boiling water is usually poured upon the drug and the heat continued to nearly the boiling point for from one to two hours. The process of DECOCTION consists in boiling the drugs in an aqueous menstruum for fifteen minutes or longer to obtain their soluble properties. This may be done in an open or covered vessel, but the process is now but little employed. The water-bath percolator is a very convenient apparatus for decoctions, as the heat may be maintained to boiling for any length of time, and the liquid then drawn off by the stop-cock. MACERATION. When percolation came to be the officinal process for ex- hausting drugs, maceration, the process of our forefathers, was mostly abandoned, but we are glad to see that in the pres- ent pharmacopoeia its value is again recognized, and that many preparations, which have of late been made by percola- tion, arc now again made by maceration. In addition to this, the new pharmacopoeia, in making most of the tinctures and some extracts, gives the very much needed direction to macerate twenty-four hours with a portion of the menstruum before packing in the percolator. Maceration is the necessary primary Step to successful percolation. It softens the drug. 34 WORKING PROCESSES — PERCOLATION. dissolves its soluble properties and loads the menstruum with them, ready to be carried away by the subsequent process of percolation. The new British Pharmacopoeia (1885) directs maceration for from twenty-four to forty-eight hours as a preliminary step to percolation in making tinctures, etc. The German, French, and other continental European authorities direct maceration mainly for obtaining the strength of drugs ; and although percolation, when properly conducted, has great advantages over any other process for obtaining the strength of drugs, without maceration it fails to accomplish its full purpose. Whenever percolation is employed, sufficient time should be given for maceration to loosen and dissolve the soluble proper- ties of the drug. If alcohol is the menstruum employed, the maceration may be conducted after packing the percolator; but if water forms a portion of the menstruum, the drug should first be macerated with a portion of the menstruum sufficiently long to allow it to swell before it is packed in the percolator. Any convenient covered vessel may be used for macerating drugs designed to be percolated. For small quantities, glass, specie or salt mouth jars, earthen-ware fruit jars, or covered granite-ware stew-pans, are very convenient, even tin cans will not be injurious for most drugs. Drugs to be thus macerated should be thoroughly moistened with a portion of the men- struum and covered to prevent exposure and evaporation. When preparations are prepared entirely by maceration, the drugs should be put in a suitable glass jar or vessel, the men- struum added, and be frequently agitated for several days. PERCOLATION. The directions for percolation are very complete and minute in the present pharmacopoeia ; they are therefore repeated here in full ; •• The process of percolation or displacement directed in this (1880) Phar- macopoeia consists in subjecting a substance or substances in powder con- tained in a vessel called a percolator, to the solvent action of successive WORKING PROCESSES — PERCOLATION. 35 portions of menstruum, in such a manner that the liquid as it traverses the powder in its descent to the recipient, shall be charged with the soluble portion of it, and pass from the percolator free from insoluble matter. " When the process is successfully conducted, the first portion of the liquid or percolate, passing through the percolator will be nearly saturated with the soluble constituents of the substance treated ; and if the quantity of menstruum be sufficient for its exhaustion, the last portion of the percolate will be destitute of color, odor and taste, other than that possessed by the menstruum itself. " The percolator most suitable for the quantities contemplated by this Phar- macopoeia should be nearly cylindrical, or slightly conical, with a funnel- shaped termination at the smaller end. The neck of this funnel-end should be rather short, and should gradually and regularly become narrower toward the orifice, so that a perforated cork, bearing a short glass tube, may be tightly wedged into it from within until the end of the cork is flush with its outer edge. The glass tube, which must not protrude above the inner surface of the cork, should extend from one and one-eighth to one and one-half inch (three or four centimetres), beyond the outer surface of the cork, and should be provided with a closely fitting rubber tube, at least one-fourth longer than the percolator itself, and ending in another short glass tube, whereby the rubber tube may be so suspended that its orifice shall be above the surface of the menstruum in the percolator, a rubber band holding it in position. " The dimensions of such a percolator, conveniently holding 500 grammes of powdered material, are preferably the following : Length of body, fourteen inches (36 centimetres) ; length of neck, two inches (5 centimetres) ; internal diameter at top, four inches (10 centimetres) ; internal diameter at beginning of funnel-shaped end, two and one-half inches (6.5 centimetres) ; internal diameter of the neck, one-half inch (12 millimetres), gradually reduced at the end to two-fifths of an inch (10 millimetres). It is best constructed of glass, but, unless so directed, may be constructed of a different material. " The percolator is prepared for percolation by gently pressing a small tuft of cotton into the space of the neck above the cork, and a small layer of clean and dry sand is then poured upon the surface of the cotton to hold it in place. " The powdered substance to be percolated (which must be uniformly of the fineness directed in the formula, and should be perfectly air-dry before it is weighed) is put into a basin, the specified quantity of menstruum is poured on and it is thoroughly stirred with a spatula, or other suitable instrument, until it appears uniformly moistened. The moist powder is then passed through a coarse sieve — No. 40 powders, and those which are finer, requiring No. 20 sieve, whilst No. 30 powders require a No. 15 sieve for this purpose Powders of a less degree of fineness usually do not require this additional treat- ment after the moistening. The moist powder is now transferred to a sheet of thick paper and the- whole quantity poured from it into the percolator. It is then shaken down lightly and allowed to remain in that position for a pi riod varying from fifteen minutes to several hours, unless otherwise directed ; after which the powder is pressed, by the aid of a plunger of suitable dimensions, 36 WORKING PROCESSES — PERCOLATION. more or less firmly, in proportion to the character of the powdered substance and the alcoholic strength of the menstruum ; strongly alcoholic menstrua, as a rule, permitting firmer packing of the powder than the weaker. The perco- lator is now placed in a position for percolation, and, the rubber tube having been fastened at a suitable height, the surface of the powder is covered by an accurately fitting disk of filtering paper, or other suitable material, and a sufficient quantity of the menstruum poured on through a funnel reaching nearly to the surface of the paper. If these conditions are accurately observed, the menstruum will penetrate the powder equally until it has passed into the rubber tube and has reached, in this, the height corresponding to its level in the percolator, which is now closely covered to prevent evaporation, and the apparatus allowed to stand at rest for the time specified in the formula. " To begin percolation, the rubber tube is lowered and its glass end intro- duced into the neck of a bottle previously marked for the quantity of liquid to be percolated, if the percolate is to be measured, or of a tared bottle, if the percolate is to be weighed ; and by raising or lowering this recipient, the rapidity of percolation may be increased or lessened as may be desirable, observing, however, that the rate of percolation, unless the quantity of material taken in operation is largely in excess of the pharmacopceial quantities, shall not exceed the limit of ten to thirty drops in a minute. A layer of menstruum must constantly be maintained above the powder, so as to prevent the access of air to its interstices, until all has been added, or the requisite quantity of percolate has been obtained. This is conveniently accomplished, if the space above the powder will admit of it, by inverting a bottle containing the entire quantity of menstruum over the percolator in such a manner that its mouth may dip beneath the surface of the liquid, the bottle being of such shape that its shoulder will serve as a cover for the percolator. " When the dregs of a tincture, or similar preparation, are to be subjected to percolation, after maceration with all or with the greater portion of the menstruum, the liquid portion should be drained off as completely as possible, the solid portion packed in a percolator, as before described, and the liquid poured on, until all has passed from the surface, when, immediately, a suffi- cient quantity of the original menstruum should be poured on to displace the absorbed liquid, until the prescribed quantity has been obtained." The foregoing officinal directions cover the whole general subject of percolation, and the remarks which follow are in- tended as special consideration of improved methods, and the difficulties which may arise in applying a general rule to the treatment of a variety of substances. The fineness of powder-to be used for percolation has been dis- cussed under the article on fineness of powders, but it may be here repeated that the powders directed in the formulas of the pharmacopoeia are, as a rule, too fine for successful percolation, and that the mass of druggists will have "better luck" to WORKING PROCESSES — PERCOLATION. 37 choose a grade coarser powder than is specified in the officinal formulae. Moistening the drug is discussed in the officinal process, and in the article on maceration, and it need only be remarked that it is of great importance to have the drug thoroughly and evenly moistened. Many druggists are in the habit of putting the drug in the percolator and pouring the menstruum upon it to moisten it, without even stirring it up ; this should never be done, for, frequently, a portion of the drug will " cake " so that it will not become moistened during the entire process of per- colation. The drug should always be moistened in a basin or other vessel, before putting into the percolator. Macerating before percolating is discussed in the article on maceration. It may be here repeated, however, that when water is used as" a portion of the menstruum for percolation, the drug should be moistened with the menstruum and allowed to macerate for twenty-four hours, in order that it may swell before, instead of after, packing in the percolator. Packing the percolator. In packing the percolator much depends upon the nature of the drug, the fineness of the pow- der, etc. Loose, fibrous, or bulky drugs, such as arnica, stillingia, buchu, etc., cannot be packed very firmly, but should be made as compact as possible ; heavy drugs, such as aconite root, valerian, golden seal, etc., do not require so much pres- sure, but will pack much firmer; soft, spongy, or gummy drugs, such as rhubarb, colocynth or squill, should not be packed very firmly; coarse powders, as a rule, should be packed more firmly than fine. The percolator should be packed from the outside towards the centre and as evenly as possible. A disc of paper and then a cover of perforated tin should be placed upon the surface of the powder after it is packed to secure the even distribution of the menstruum as it is poured upon the drug. A glass or earthenware weight may be used with advantage to hold the drug in its place. It should generally be allowed to macerate for some time after the men- struum is poured on before beginning to percolate. The flow of percolate maybe regulated by the rubber tube, as directed in the officinal process; by a loose cork in the bottom of the percolator; or, if the water-bath percolator is 38 WORKING PROCESSES — PERCOLATION. used, by the stop-cock. The rapidity with which the percolate should flow, depends very much upon the nature of the drug, and the quantity required to be obtained as compared with the quantity of drug being percolated ; for example, fluid extracts should not be percolated so rapidly as tinctures, nor aconite as rapidly as buchu. With a certain class of drugs, the alcoholic or hydro-alcoholic menstruum, with which the percolation is conducted, may be forced out by adding water after the menstruum has dis- appeared from the surface of the drug, and thereby make a saving of alcohol ; but with others, which soften or make pre- cipitates with an aqueous menstruum, the percolation must be conducted to the end with the same menstruum. The men- struum remaining in the drug after percolation, may be pressed out with a tincture press and the alcohol recovered from it by distillation. Drugs Difficult to Percolate. Many drugs present difficulties to the ordinary methods of percolation and require special treatment ; this is generally given in the formula; in which they are found ; but they may be classed in a general way as follows : i. Drugs that soften or make a pulpy mass upon the addi- tion of the menstruum, such as orange, gentian, rhubarb, squill, colocynth, etc. Such drugs should be well moistened and macerated before packing ; they should be rather coarsely powdered and rather loosely packed, and the percolation, when begun, should be conducted rapidly, and continued to the end with the same menstruum. 2. Gums and gum-resins which agglutinate or mass together when the menstruum is added. These should be mixed with an equal bulk of sand, sawdust, or rice chaff, and not packed, but placed loosely, in the percolator, and the percolation con- ducted in the usual manner. 3. Bulky drugs, like arnica, buchu, chamomile, etc. Although these drugs are not difficult to percolate, they absorb so much menstruum that the expense of making their preparations is considerably increased. These should be WORKING PROCESSES — PERCOLATION. 39 packed as firmly as possible, and held down in the percolator with a weight during the process of percolation. Economy in Percolating and Filtering. [Much loss of Alcohol occurs by evaporation when the ordinary percolator or filtering funnel are left uncovered during percolation or filtration. To remedy this difficulty a simple apparatus may be constructed by any druggist who will take the trouble. It is shown in use in the following cut : A, is the wooden cover, large enough to lit the top of a per- colator or funnel; it is bound with a wooden hoop, whose lower edge projects about half an inch below the under surface 40 WATER-BATH PERCOLATION. of the cover ; to the wooden hoop is tacked a piece of moderately thin-sheet rubber, so that the cover when com- pleted, is like a drum-head, and, when it is used to cover a per- colator or funnel, will make, by its elasticity, an air-tight covering. B, is a funnel tube, so bent as to prevent evaporation or access of air. Through it, fresh menstruum or other liquid may be introduced into the percolator or funnel. A glass or metal tube answers the same purpose, and may be stopped with a cork. This tube may be adjusted by boring a hole in the wooden cover and punching a smaller hole in the rubber, so that it will fit snug around the tube. C, is a rubber tube attached at one end to a glass tube in the cover (which passes through the rubber as heretofore de- scribed), and at the other end to a tube in the stopper of the receiving bottle. This tube allows the air to pass from the receiving bottle into the percolator, and as the liquid fills the bottle the air is forced from it into the percolator or funnel. B, is a rubber tube attached to the percolator that connects with a tube in the stopper of the receiving bottle, through which the percolate passes ; if the lower end of the percolator is too large for the rubber tube, a perforated cork, into which a glass tube is inserted, may be placed in the neck of the percolator for this purpose, as is directed in the pharmacopoeia process. By raising or lowering the percolator or the receiving bottle the flow of the percolate can be made more or less rapid, as it works on the principle of the syphon. The receiving bottle may be made of any wide-mouth bottle, holes being bored in the cork for the insertion of the tubes to which the rubber tubing is attached. E, shows the perforated diaphragm of the percolator. With this simple arrangement percolation or filtration can be carried on for any length of time without exposure or loss by evaporation. WATER-BATH PERCOLATION. The process of water-bath percolation consists in subjecting the powder contained in a percolator, surrounded by water, WATER-BATH PERCOLATION. 41 to the action of a warm menstruum during the entire process of maceration and percolation. By the means of the water- bath the menstruum and powder are kept at any desired degree of heat for any length of time.* It is claimed for this process, that the heat employed is of great aid in effecting the solution of the soluble constituents of the substance or substances which are being exhausted, and therefore, that it is much more rapid, efficient and economical than the ordinary method of percolation. By consulting the solubility tables, which may be found in the pharmacopoeia and other standard works, it will be seen that the medicinal principles of vegetable drugs (especially the * The process of water-bath percolation as applied to pharmaceutical prepa- rations and the apparatus, FENNER'S water-bath percolator and still, were patented February 7, 1882. The process is an application of the well-known fact that a heated men- struum dissolves the soluble portions of drugs much more readily and to a much greater extent than the same menstruum when cold. The apparatus is constructed with the view of serving its purpose in the best possible manner, and since its introduction it is coming rapidly into use in all parts of the country. The following is a description and sectional view of the apparatus : It consists of a Percolator, A, suspended in a water-bath and connected externally by a stop-cock through which the percolate is received, and a Still, B, which may be adjusted whenever it is needed. The percolator, A, is also the vessel into which liquids are put for evaporation and distillation. The percolator may be removed by unscrewing the stop-cock at b, and lifting it out of the water- bath. It should be removed after using in order to dry the apparatus. The perforated diaphragm at / prevents the llj^K drug packing in the neck of the percolator and wui-tN-xoM thereby hindering percolation. The flow of tin- percolate can be regulated by the stop-cock ; it also serves to draw off the residue after distillation or evaporation, The vessel surrounding the Percolator is designed for water which is to be heated when desired, forming a water-bath for the Percolator and its contents. The Still //, can be adjusted when desired, by setting it into the percolator or water-hath. The vapor rises to the inner surface of the cone of the- Still. 42 WATER-BATH PERCOLATION. alkaloids and other substances in which their value chiefly consists), are from several to several hundred times more soluble in boiling water or alcohol than in cold. Although the heat employed in water-bath percolation is seldom so high as boiling alcohol or water, yet the solubility of the medicinal principles is relatively increased according to the heat employed ; and, as the object of percolation is to exhaust the drug of. its soluble medicinal agents no other argument than this for the application of heat during percolation seems nec- essary, for it is evident that the value of the drug is much more faithfully represented in preparations made in this manner, and, that in making fluid or solid extracts, or other concentrated preparations, a much less quantity of menstruum is required to exhaust the drug, than when cold percolation is employed. As the question may be asked by many if heat does not injure the preparations, it may be here stated that the degree of heat directed cannot be injurious, as it is insufficient to volatilize any of the medicinal principles of the drugs. is condensed by the cold water on the outer surface of the cone, and the dis- tillate is discharged in the form of a liquid at a, being conducted through a rubber tube to any convenient receptacle. The following cut represents the Water-bath Percolator and Still detached and in use as a percolator. When used for distilling, the cover of the percolator is to be removed and the still top adjusted as heretofore described. When used for evaporating, the cover of the percolator is to be removed, and the evaporation conducted in the ordinary way. The water-bath percolator can be used as readily for cold percolation as for warm, and, in short, when all things are considered it is the most serviceable, economical and convenient per- colator in use. These Water-bath Percolators and Stills are now being used to a large extent in all parts of the country, and the reports received from parties who have thoroughly tested them are very flattering. At no distant day the process of water-bath percolation is bound to super- sede the ordinary method of percolating as completely as percolation, when it was introduced, superseded the process of maceration. WATER-BATH PERCOLATION. 43 The method of conducting water-bath percolation is as follows : The powdered drug is to be moistened with a portion of the menstruum and either packed in the percolator at once, or after macerating twenty-four hours, as the formula may direct. A certain quantity of menstruum (as directed in the formula) is then to be poured upon the drug and it is allowed to mace- rate for a specified time in a warm place. It is then to be heated (as directed in the formula) for a certain length of time and the percolation then begun and continued until the drug is exhausted, or until the required amount of percolate is obtained. The same general directions for packing the percolator, keeping the drug covered with the menstruum, regulating the flow of the percolate, etc., as are specified in the officinal process, should be observed. In the formulas contained in this book for making prepara- tions by water-bath percolation, it is directed after packing in the percolator and adding menstruum to the drug, to " set in a warm place" for a certain length of time to macerate; by this it is meant that the percolator and its contents should be heated from 30 to 35 C. (86° to 95 F.) by any convenient means. In summer a warm place in the store will suffice ; in winter a shelf by the stove or other heating apparatus will do; or a box, with a hinged door and holes in the bottom about the size of the bottom of the percolators, may be fastened to the side of tlie wall and the heat may be maintained by a coal oil lamp placed beneath the percolator. In large establishments warming closets heated by steam pipes or other means may be arranged. It is not absolutely necessary that heat should be maintained during maceration, but better results will follow if it is. The direction in the formulae "heat very moderately" means that the temperature should not be higher than from 40 to 45° C. (104 to 1 1 3 F.); "heat moderately" means that the' temperature should not exceed 6o° to 65 C. (140° to 149° F.) — a higher temperature than this is seldom necessary. After the percolation is concluded, if sufficient Alcohol is 44 SOLUTION. — WASHING PRECIPITATES. retained in the drug to be of value, it may be recovered by distillation. The amount of alcohol or other menstruum retained varies with the nature of the drug — from one-fourth to more than its entire original weight. In making any consid- erable quantity of a preparation, it is important to save this menstruum, which would otherwise be wasted, by distillation, as stated in the article on distillation. SOLUTION. Solution is the process of dissolving solids or fluids by means of other solids or fluids which combine with them and hold them in a liquid state. The most common forms of solu- tions are those in which a liquid is dissolved in another liquid, as, for example, an essential oil in alcohol, or a solid in a liquid, as sugar in water ; but some solutions are made by the action of solid substances upon each other, as when camphor and hydrate of chloral are combined. No special apparatus is required for making solutions. Many are made cold, while some are aided by heat with such appliances as druggists usually possess. The solution of some substances is facilitated by reducing them to a fine powder, while others, as scale salts, etc., are best dissolved without being made fine. In dissolving by the aid of heat the water- bath is much employed. WASHING PRECIPITATES. The object of washing fresh precipitates is to free them from soluble salts, or other substances with which they are associated, which are soluble in water. The usual manner of washing fresh precipitates, in a small way, is to pour them upon a wet muslin strainer and filter water through them until the soluble matter has all been washed out. This method is open to several objections: ist, exposure to the atmosphere, which rapidly oxidizes many salts, especially WASHING PRECIPITATES. 45 the iron salts, rendering them insoluble ; 2d, waste, as consid- erable of the precipitate is washed away by this method ; 3d, inconvenience, as it requires the continued attention of the operator. Another method is to wash the precipitate in a large jar or earthenware crock, by pouring upon it a quantity of water and stirring thoroughly, then allowing the precipitate to settle, drawing off the supernatant fluid with a syphon, pouring on more fresh water, and thus continuing until the soluble matter is washed out ; and then draining the precipitate upon a muslin strainer. The best method, however, is to make the precipitate in a tall jar or crock, filled full of water; then, having fastened a piece of rubber tubing to each end of a stick, insert it in the jar in such a manner that a stream of water passing through one rubber tube will reach to the bottom of the vessel, while the water at the top of the jar will be carried off by means of the other tube, which acts as a syphon. The water to wash the precipitate can be supplied from a water-pipe, or from a bucket set above the washing apparatus, into which the tube is inserted as a syphon. The same result will be accomplished by 'running the tube, through which the water is supplied, to the bottom of the jar and allowing the water to overflow at the top. It will be seen that by this means the precipitate is con- tinually washed, and that it is not exposed, nor wasted, as only clear water is drawn off at the top of the jar, because the precipitate has time to settle away from the surface of the water where the waste tube is attached. Precipitates are rapidly and thoroughly washc'd by this method. When the soluble substances have all been washed out, the precipitate should be poured upon a muslin strainer to drain, the water may then be pressed out and the precipitate dissolved, or dried as required. PART III WORKING FORMULA. In the formulae which follow we have endeavored to include all preparations generally used or called for that can readily be prepared by druggists. We have made no distinction between officinal and unofficinal formulae, except to note the former when the original text is followed. For more convenient reference and comparison we have attempted to classify the preparations as nearly as possible under appropriate headings. We have endeavored to make the formulae as plain, explicit and comprehensive as possible, and have avoided as much as possible the use of technical terms and tedious processes. The formulae are made from actual work in the shop or laboratory, and are therefore WORKING Formulae, which cannot fail to give good results, provided they are carefully followed and good material is used. In submitting them to our friends, it is with the earnest hope that they may contribute something to that store of knowledge which raises the pharmacist above the mere tradesman, and that their use may put many a dollar in the pocket of the druggist, which otherwise would be paid as profit to manufacturers. ABSTRACTA— ABSTRACTS. These preparations are properly extracts of vegetable drugs so diluted with Sugar of Milk that they represent the soluble medicinal value of two parts of the drug in one part of the abstract. They were introduced in the 6th Revision of the U. 46 ABSTRACTS. 47 S. Pharmacopoeia, to supply a popular demand for " Powdered Extracts " ; but as they are only double the strength of the drug their value for such a purpose is questionable. They have not as yet become popular, and it is doubtful if they are retained in a subsequent revision of the Pharmacopoeia. The U. S. Pharmacopoeia process for abstracts is in sub- stance as follows : Exhaust 200 parts of the drug, by percolating with sufficient menstruum, reserving the first 170 parts that pass; evaporate the remaining percolate to 30 parts, adding it to the portion reserved ; then add 50 parts Sugar of Milk ; allow to evapor- ate slowly to dryness ; powder, and add enough Sugar of Milk to make 100 parts. The quantitive formulae for the officinal abstracts are as follows : 1. Abstractum Aconiti. Abstract of Aconite. Aconite (root), 200 parts. Tartaric Acid, 2 parts. Alcohol, Sugar of Milk, each sufficient to make . 100 parts. 2. Abstractum Belladonnae. Abstract of Belladonna. Belladonna (root), 200 parts. Alcohol, Sugar of Milk, each sufficient to make . 100 parts. 3. Abstractum Conii. Abstract of Conium, Conium (fruit), 200 parts. Diluted Hydrochloric Acid, 6 parts. Alcohol Sugar of Milk, each sufficient to make . 100 parts. 4. Abstractum Digitalis. A bs tract of Digitalis. Digitalis (leaves) 200 parts. Alcohol Sugar of Milk, each sufficient to make . lOO parts. 48 ABSTRACTS. 5. Abstractum Hyoscyami. A bstract of Hyoscyamiis. Hyoscyamus (leaves) '• . . . 200 parts. Alcohol, Sugar of Milk, each sufficient to make . 100 parts. 6. Abstractum Ignatiae. Abstract of Ignatia. Ignatia (seed or bean), 200 parts. Alcohol 8, to Water 1 part, Sugar of Milk, each sufficient to make . 100 parts. 7. Abstractum Jalapae. Abstract of Jalap. Jalap (root or tuber) 200 parts. Alcohol, Sugar of Milk, each sufficient to make . 100 parts. 8. Abstractum Nucis Vomicae. Abstract of Nux Vomica. Nux Vomica (seed), 200 parts. Alcohol 8, to Water 1 part Sugar of Milk, each sufficient to make . 100 parts. 9. Abstractum Podophylli. Abstract of PodopJiyllum. Podophyllum (root) 200 parts. Alcohol, Sugar of Milk, each sufficient to make . 100 parts. 10. Abstractum Senegae. Abstract of Senega. Senega (root) 200 parts. Alcohol, Sugar of Milk, each sufficient to make . 100 parts. ABSTRACTS. 49 11. Abstractum Valerianae. Abstract of Valerian. Valerian (root), 200 parts. Alcohol, . Sugar of Milk, each sufficient to make . 100 parts. 12. Abstracts, by Water-Bath Percolation. It is obvious that drugs from which abstracts are to be made may be much more readily and economically exhausted by water-bath percolation than by the cold process — much less menstruum being required to exhaust the drug^ and the result much more perfectly representing the active medicinal agents. The following sample formula, which corresponds with the official strength, but differs in manner of making, will serve as a general formula for making abstracts by water- bath percolation. Abstracts of other drugs may be made in the same general manner, by using the menstruum which is best suited to obtain the medicinal value of the drug without obtaining an unnecessary quantity of worthless extractive matter. The menstruum which is employed for making the Fluid Extract of the drug (see Fluid Extracts) will generally be proper to use for making the abstract. 13. Abstract of Aconite. Aconite (root), No. 60 powder, .... 16 ounces. Tartaric Acid, 75 grains. Alcohol, Sugar of Milk, in fine powder, each suffi- cient to make, 8 ounces. Moisten the drug with 6 ounces of Alcohol, and pack very firmly in the water-bath percolator. Pour upon it 10 ounces of Alcohol and set in a warm place for three days; then heat moderately [to about 6o° C. (140° F. 1 1, and after one hour begin t" percolate, adding Alcohol t<> the drug, and continuing the heat until 12 ounces have passed, which reserve. Con- tinue the percolation until the drug is exhausted (<>r until 50 ACETA — ACETATES — VINEGARS. about 12 ounces more have passed). Evaporate this last percolate by distillation to about 3 ounces, and add to the portion previously reserved. Dissolve the acid in the liquid, add 4 ounces of powdered Sugar of Milk, and set aside in a moderately warm place [not over 50 C. (122 F.)], in an evaporating dish covered with gauze. Let remain until evaporated to dryness, then powder, weigh, and add enough powdered Sugar of Milk to make 8 ounces. The Alcohol remaining in the drug after percolation may be recovered by distillation. ACETA— ACETATES— VINEGARS. Acetates. — Acetates are chemical or pharmaceutical products in which acetic acid is used as a combining factor, or a solvent for medicinal principles. The Acetates may be conveniently classed as follows : Chemicals, in which Acetic Acid unites with Alkalies, Alka- loids, or metallic bases to form chemical salts ; as Acetate of Potassium, Acetate of Morphine, Acetate of Lead, etc. Solutions, in which Acetic Acid is combined with some base but not sufficiently concentrated to crystallize, as solution or liquor Acetate of Ammonium, solution Acetate of Iron ; or simple solutions of Acetic salts in water or other liquid, as solution Acetate of Morphine, etc. Tinctures, in which an Acetic solution is diluted with an alcoholic liquid, as tincture Acetate of Iron. Vinegars, in which the medicinal value of the drug is ob- tained by Acetic or diluted Acetic Acid as a menstruum. In this class is included the Acetic fluid extracts, and the proper aceta or vinegars which have long been known as pharma- copceial preparations, and which will now be considered. The Vinegars which were once quite popular galenicals are now but little used ; they still hold their place, however, in the pharmacopoeias. In the formulae for Vinegars which follow •we have found it impracticable to exactly follow the pharma- copoeias, because of the difference in name and acid strength of Dilute Acetic Acid directed by different authorities, and VINEGARS. 51 some other peculiarities. We have therefore adopted a general 10 per cent. Standard of the active ingredient, and generally the Diluted Acetic Acid of the U. S. Pharmacopoeia which contains 6 per cent, of real Acetic Acid. We have also added a small percentage of Alcohol in most of them, as is customary in Continental Europe, because we are satisfied that it is an advantage to the preparations. If fluid extracts are used instead of crude drugs this addition will be unnecessary. 14. Acetum — Vinegar. Vinegar was formerly officinal in the U. S. Pharmacopoeia, but is now deleted. It is still retained in the British, German and many other Pharmacopoeias. It should contain from 5^2 to 6 per cent, of absolute Acetic Acid. When directed to be used, the ordinary com- mercial Vinegar may generally be employed or Diluted Acetic Acid of the U. S. Pharmacopoeia, which contains about the same percentage of Acid, may be used instead of it. Acetification. — Acetification is the process by which Sac- charine or hydro-alcoholic liquids are converted into vinegar. It consists in the partial dehydration and subsequent oxidation of the liquids by contact with the atmosphere. Domestic vinegar-making is carried on in nearly every household by exposing cider, saccharine or vinous liquids to heat and air. In a large way vinegar is manufactured by running the liquids many times through generators filled with beech-shavings or corn-cobs, and perforated with numerous holes to admit free circulation of air by which the oxidation is rapidly accom- plished. 15. Acetum Aromaticum. Aromatic Vinegar. (Adapted from the German and French Pharmacopoeias.) Oil of Lavender 1 part or 5 minims. Nil of Peppermint, ... I part or 5 minims. Oil of Rosemary I part or 5 minims. Oil of Juniper, .... 1 part or 5 minims. 52 ACETA — VINEGARS. Oil of Cinnamon, .... i part or 5 minims. Oil of Lemon 2 parts or 10 minims. Oil of Cloves, 2 parts or 10 minims. Alcohol, 300 parts or 31^ fl. ounces. Diluted Acetic Acid, . 450 parts or 5 fl. ounces. Water, 1,200 parts or 13 )/± fl. ounces. Dissolve the oils in the Alcohol, add the Acid and Water, and, after standing a few days, with frequent agitation filter through paper. This is used as an Aromatic toilet preparation and some- times internally as a mild Aromatic Acid. Several proprietary articles similiar to this, as Bully's Aro- matic Vinegar, etc., etc., have a popular sale as toilet requisites. 16. Acetum Cantharidis. Vinegar of Cantharides. (ADAPTED FROM THE BRITISH PHARMACOPCEIA, 1885.) Cantharides, bruised, . . . I part or 455 grains. Glacial Acetic Acid, . . . 1 fl. part or 1 fl. ounce. Acetic Acid, sufficient to make, 10 fl. parts or 10 fl. ounces. Mix 6 J / 2 fl. ounces of the Acetic Acid with the Glacial Acetic Acid, and the Cantharides in a strong well-stopped quart bottle. Digest the mixture in a water-bath by boiling gently for two hours, then transfer to a glass percolator and perco- late, adding enough Acetic Acid through the drug in the per- colator to make 10 fl. ounces. It will be observed that this is made with strong Acetic Acid instead of dilute as is usual with the Vinegars. This is a strong vesicant used for blistering. It may be applied with a camel-hair pencil. 17. Acetum Colchici. Vinegar of Colchicum Seed or Tuber {Root). Colchicum Seed or Tuber in coarse powder, 729 grains. Alcohol, \y 2 fl. ounces. Diluted Acetic Acid, sufficient to make . 16 fl. ounces. Mix the alcohol with three ounces of the Diluted Acetic Acid, and macerate the powder in the mixture for 24 hours; ACETA — VINEGARS. 53 then transfer to a glass percolator, and percolate, adding, when the liquid has disappeared from the top, diluted Acetic Acid, and continuing the percolation until 16 fl. ounces are obtained. This preparation is officinal in several of the European Pharmacopoeias. It is preferably made from the tuber (root), and is a very good preparation of Colchicum, but is not much used in this country. It is given for rheumatism and gout, the dose being from 5 to 30 minims. 18. Acetum Digitalis. I r inegar of Digitalis. Digitalis Leaves, in coarse powder, . . 729 grains. Alcohol 2 fl. ounces. Diluted Acetic Acid, sufficient to make 16 fl. ounces. Make in the same manner as Acetum Colchici. A heart stimulant, diuretic and nervine. Dose )4 to I fl. drachm, not exceeding 3 fl. drachms per day. This corresponds very nearly to the formula of the German Pharmacopoeia. 19. Acetum Lobeliae. J'iuegar of Lobelia. Lobelia Herb in coarse powder, . . 729 grains. Alcohol, 2 fl. ounces. Diluted Acetic Acid sufficient to make 2 fl. ounces. Make in the same manner as Acetum Colchici. An emetic, expectorant, antispasmodic, etc. Dose 5 to 30 minims. This corresponds with the United States Pharmacopoeia, 1880 for- mula, except in the addition of the alcohol. 20. Acetum Opii, U. S., 1880. / 'iiugar of Opium. Opium in powder 729 grains. Nutmeg in powder 218 grains. Sugar 1458 grains. Diluted Acetic Acid, sufficient to make 16 fl. ounces. Mix tin: Opium and Nutmeg and macerate them with 12 fl. ounces of Diluted Acetic Acid for 24 hours, then drain off 54 ACETA — VINEGAR' the liquid, put the drugs in a percolator and percolate with the liquid ; dissolve the sugar in the percolate by agitation, and add enough Diluted Acetic Acid through the percolator to make 16 fl. ounces of the mixture. The addition of i*< fl. ounces of Alcohol would, in our opinion, be an advantage in this preparation. Used for the same purposes as other preparations of Opium. Dose 5 to 15 minims. The U. S., 1870, Vinegar of Opium contained 1200 grains of Opium in a pint, and care must be used in dispensing not to mistake one for the other. The following formula, which is similar to several which are officinal in Europe, is preferable to our own : 21. Acetum Opii Compositum. Aromatic Vinegar of Opium. British Black Drop. Opium in powder 729 grains. Nutmeg in powder 218 grains. Saffron in powder, j^ grains. Sugar in powder 145 8 fl. ounces. Alcohol, 2 fl. ounces. Diluted Acetic Acid, sufficient to make 16 fl. ounces. Make in the same manner as Acetum Opii. Dose 5 to 15 minims. 22. Acetum Sanguinariae. Vinegar of Blood Root. Sanguinaria in powder, 729 grains. Alcohol i 1 2 fl. ounces. Diluted Acetic Acid sufficient to make 16 fl. ounces. Make in the same manner as Acetum Colchici. A stimulant to the mucous membrane. Used mainly as an expectorant. Dose 10 to 30 minims. This corresponds with the 1880 United States Pharma- copoeia, except in the addition of the alcohol. It is officinal only in the United States. 55 23. Acetum Scillae. Vinegar of Squill. Squill, in coarse powder 729 grains. Alcohol, 1^2 fl. ounces. Diluted Acetic Acid sufficient to make 16 fl. ounces. Make in the same manner as Acetum Colchici. Expectorant and Diuretic. Dose 10 to 60 minims. This corresponds with the 1880 United States Pharma- copoeia, except in the addition of Alcohol. The British Pharmacopoeia, 1885, formula nearly corresponds with the U. S. 1870 — directing 1 part of squill in 8, instead of 1 in 10 as above. ACIDA— ACIDS. A great variety of widely different chemical substances are classed and included under the general name Acids. In a popular sense acids are substances having a sour taste and capable of turning vegetable blues red; but in chemistry, acids are compound substances having one common and essen- tial property, viz., that of combining with metallic bases, alkalies or alkaloids to form new compounds which are called salts. As Hydrogen is a constant element in all acids it is called the Acid former, and an acid must be considered a salt whose metal is hydrogen, which is displaced in part or wholly when salts are formed with other bases. Several substances are classed among the acids which are not properly acids but anhydrides ; for example, Carbonic Acid Gas C0 2 , Arsenious Acid As 2 2 , Chromic Acid Cr0 3 , etc. These arc not true acids, because they do not contain hydrogen. Acids are gaseous, liquid or solid, and are classed as inor- ganic and organic, the inorganic being mostly derived from mineral, and the organic from vegetable and animal substances. The mineral acids are but little used in medicine except when compounded with other drugs, but the salts formed by their union with bases comprise a large share of the chemicals em- ployed by pharmacists. The organic acids are very numerous and form an important class of pharmaceutical products, com- 56 ACIDA — ACIDS. prising the valuable medicinal properties of many vegetable and animal substances. In pharmacy the Latin name of the acid follows Acidum, as Acidum Nitricum, but when rendered in English the name precedes the generic term, as Nitric Acid. In chemistry the names and their terminations generally indicate the composi- tion of the acid, as hydrogen nitrite HN0 2 (Nitrous Acid); hydrogen nitrate, HN0 3 (Nitric Acid). Acidification is the chemical process by which substances combine to form acids, or the state in which they exist in nature as acids. The following tables of acids most frequently used in pharmacy will be convenient for reference. The strength and nomenclature of acids officinal in the United States corre- spond with the present U. S. P. The solid acids are more properly classed with chemicals, and are so numerous that only those most frequently used in pharmacy can be mentioned : LIQUID ACIDS FREQUENTLY USED. NAME OF ACID. Chemical Symbol. Specific Gravitj-. Real Acid' sorBrF per cent. bUL Ken. Acetic .1 HC 8 H 3 3 • C G H 3 HO ) . HCH 8 HI .! HBr HCl FICN • H 3 PO, • HC 3 H 5 3 IINO3 .'UHNOgisHCl • HC 18 H 83 2 ) H 3 P0 4 ! H a S0 4 ! so 2 . HC 5 H 9 3 I.O48 1.00S 1-057 1.060 1.065 1.063 1.077 1.077 1. 160 1.049 0.997 1.060 1. 212 1.040 1.042 1.059 1. 215 1-043 0.875 1-347 1-057 1.S40 1.0S2 1.022 o.935 36- 6. 99. IOO. 90. 25- 10. 10. 3i-9 10. 2. 10. 75- 11. 2 69.4 10. 39-S 12. 1 95- 5o. 10. IOO. 10. 3-5 IOO. ["From Wood, < etc., by distil- *Carbolic, or Phenic Carbolic, Liquified (Br. 1885 Formic 1 \ From Coal Tar ( by distillation \ From Ants, { etc. Ilydrobromic, Diluted Hydrochloric (Muriatic) Hydrochloric, Diluted Hydrocyanic, Diluted Hypophosphorous, Diluted. Lactic Lactic, Diluted, (Br. 1885). . Nitric Nitric, Diluted From Bromine. \ From Chlorides I and H 8 S0 4 \ From Cyanides J and H 8 S0 4 \ From Phos- ( phorus. i From Sour j Milk, etc. \ From Nitrates ] and H 2 S0 4 . - Mixed Acids. From Fats. ( From Phospho- ] } rusandHNO a \ From SO, and Nitro-hydrochloric, Diluted . Oleic Phosphoric (Orthophosphoric ( HNO s . Valerianic , From Valerian. Carbolic Acid liquifies at about 95 F. The Sp. gr. mentioned is taken at its melting point. ACIDS. SOLID ACIDS FREQUENTLY USED. NAME OF ACID. Chemical Symbol. Molecular Weight. Arsenious (Anhydride) As 2 3 Benzoic HC r H 5 2 Boric or Boracic H 3 B0 2 Chromic (Anhydride) Cr0 3 Citric H 3 C c H 3 7 H 2 Gallic HC r H 3 5 H 2 Oxalic H 3 Co0 4 2H 2 Phenic or Carbolic C 6 H 5 HO Phosphoric, Glacial HP0 3 Picric or Carbazotic : C 6 H 3 (N0 2 ) 3 Pyrogallic C 6 H 6 3 Salicylic HC T H 5 3 Tannic C^H^O,, Tartaric H s C 4 H 4 8 197-3 ! ( Arsenic by Subli- / mation. 122. ( Benzoin by Subli- / mation. 62. Soda Borax. \ Bichrom, Potass. / and HoS0 4 . \ Lime or Lemon / Juice. 188. From Nutgalls, etc. 126. i | Sugar or Starch, ! / and HNO,. ( Coal Tar or Petro- 94. ( leum. SO. Phosphoric Acid. 227. j Carbolic and Nitric / Acids. , \ Gallic, by Subli- / mation. 133. \ Carbolic and Car- / bonic. 322. From Nutgalls, etc. ( From Cream of 150. / Tartar. 24. Acidum Aceticum. Acetic Acid. The U. S. officinal Acetic Acid contains 36 per cent, of real Acetic Acid. The new Br. Ph. (1885) directs an acid contain- ing 33 per cent., while the German Standard directs only 30 per cent, for a corresponding preparation. Glacial Acetic Acid is* practically a pure or 100 per cent. acid, therefore the U. S. officinal Acid may be prepared from it, if desired, by taking Glacial Acetic Acid, Distilled Water, . 36 parts, or ^ l /> ounces av. 64 parts, or 8 ounces av. The official Acetic Acids of othei made in the same manner relatively. pharmacopoeias may be 58 ACIDA — ACIDS. 25. Acidum Aceticum Dilutum. Diluted Acetic Acid. Acetic Acid (36 per cent.), 1250 grains or 2^5 fl. ounces. Distilled water sufficient to make a pint. Mix. This is the base of the U. S. official Aceta, and is about the same acid strength as good vinegar. 26. Acidum Aceticum Glaciale. Glacial Acetic Acid. This is prepared by adding concentrated Sulphuric Acid to freshly fused Acetate of Sodium in a retort and distilling. It contains from 90 to 99 per cent, of absolute Acetic Acid. The German Pharmacopoeia very properly calls this Acetic Acid, Essigsaure, while it calls the 30 per cent, preparation Diluted Acetic Acid, Verdunnte Essigsaure. In making up German formulas or prescriptions this should be remembered, as they have no preparation that corresponds to our Dilute Acetic Acid. 27. Acidum Aceticum Aromaticum. Aromatic Acetic Acid. Oil of Cloves, 3 fl. drachms. Oil of Lavender, 2 fl. drachms. Oil of Lemon, 2 fl. drachms. Oil of Bergamot 1 fl. drachm. Oil of Thyme, 1 fl. drachm. Oil of Cassia, 20 minims. Glacial Acetic Acid, 1 fl. ounce. Mix, and shake frequently until dissolved. This is used as an odorateur for smelling bottles or vinegar- ettes, and a refreshing scent for the sick room. ACIDA — ACIDS. 59 28. Acidum Carbolicum. Crystallized Carbolic Acid — Phcnic Acid or Phenol. This is prepared from coal tar and the refuse of petroleum, by treating with caustic alkalies, subsequent neutralization and distillation. Crude Carbolic Acid 'is an oily liquid largely used for disinfecting. The Crystallized Acid is used in medi- cine, and is furnished by manufacturers, of different degrees of purity; it becomes liquid at from 95 to ioo° F. 29. Acidum Carbolicum Liquidum. Liquefied Carbolic Acid. Crystallized Carbolic Acid, 100 parts or 10 ounces av. Distilled Water, .... 10 parts or 1 ounce av. Melt the acid and add the water while melted, it will then remain liquid. As carbolic acid is solid at ordinary temperatures, this makes a convenient preparation to use in place of the crystals, and as it is 90 per cent, strong it may generally be used when carbolic acid is designated or prescribed unless crystallized carbolic acid is specially mentioned. This is official in the new British and German Pharmacopoeias. The dose when given internally is from 1 to 3 minims, largely diluted. Solutions of carbolic acid in water are made varying from 1 : IOOO to 1 : 20 (5 per cent.), the latter being a saturated solution. (See " Solutions.") 30. Acidum Hydrobromicum Dilutum. Diluted Hydrobromic Acid. This contains 10 per cent, by weight of hydrobromic acid gas, HBr. It is best made by passing a current of sulphu- retted hydrogen through a solution of bromine I part in water 15 parts, distilling and diluting to a EO per cent, solution. As this process cannot be conveniently used by druggists the following formula is given, which (although it does not make 60 A( IDA — ACIDS. a perfectly pure acid) is sufficiently pure for general use, and is about the officinal strength. Bromide of Potassium 3 ounces aw Tartaric Acid, 3^5 ounces av. Distilled Water, 16 fl. ounces. Dissolve the salts separately each in 8 ounces of water and mix the solutions, agitate thoroughly and set aside in a cold place (preferably on ice) for 12 hours, then decant the clear liquid and filter. It is advantageous to let this solution remain for some time in a cool place to crystallize the acid tartrate of potassium. This is used for the same purposes as bromide of potassium, and is an excellent solvent for quinine. The dose is from 30 to 60 minims, in water. 31. Acidum Hydrochloricum. Hydrochloric Acid — Muriatic Acid. The United States officinal hydrochloric acid contains 31.9 per cent, of real acid, and is what is supplied by manufacturing chemists as C. P. hydrochloric or muriatic acid. The new British Pharmacopoeia directs about the same strength, while the German Pharmacopoeia directs an acid containing only 25 per cent, of real acid. This acid is frequently called for as oil of salt or spirit of salt. It is sometimes given as a tonic and stomachic, largely diluted with water, or used in stimulating baths. 32. Acidum Hydrochloricum Dilutum, U.S. Diluted Hydrochloric Acid — Diluted Muriatic Acid. Hydrochloric Acid, . 6 parts or 2415 grains. Distilled Water, . . 13 parts or q. s. to make a pint. Mix, and preserve in glass stoppered bottles. This contains 10 per cent, by weight of real acid, and very nearly corresponds with the British, which contains 10.58 per cent. The German officinal preparation contains 12.5 per cent, of real acid. The dose is from 10 to 30 minims. (11 33- Acidum Hydrocyanicum Dilutum. Diluted Hydrocyanic Acid — Prussic Acid. This is prepared by distilling hydrocyanic acid gas HCN from a solution of ferrocyanide of potassium and sulphuric acid, into water or water containing a small percentage of alcohol, until the solution contains 2 per cent, of the gas. It is generally prepared by manufacturing chemists in this manner, but may be prepared by druggists as follows : Cyanide of Silver, ... 6 parts or 60 grains. Hydrochloric Acid, ... 5 parts or 50 grains. Distilled Water, .... 45 parts or 1 fl. ounce. Alcohol, 10 parts or 2 fl. drachms. Mix the hydrochloric acid with the distilled water, add the cyanide of silver, and shake the whole together in a glass- stoppered bottle. When the precipitate has subsided, pour off the clear liquid and add to it the alcohol. This acid should be kept from the light in a cool place, in small glass-stoppered bottles. It is chiefly used as a sedative for nervous disorders and in cough mixtures. The dose is from 1 to 3 minims. 34. Acidum Hypophosphorosum Dilutum. Diluted Hypophosphorous Acid. This is a 10 per cent, solution of hypophosphorous acid gas H3PO0, commonly called hypophosphorous acid, prepared in a large way by boiling mirk of lime with phosphorus, and by other methods. It may readily be prepared by decomposing hypophosphite of calcium with oxalic acid and is generally so prepared by druggists, after the formula proposed by Procter (1858). Hypophosphite of Calcium (Lime), . . 480 grains. Oxalic Acid, 350 grains. Distilled Water, a sufficient quantity. Dissolve the hypophosphite in 6 ounces, and the oxalic acid in 4 ounces of water, separately, and mix the solutions. When the precipitate 1 oxalate of lime) has subsided, pour off 62 ACIDA — ACIDS. the liquid, and reserve ; transfer the moist precipitate to a filter, pour upon it 3 ounces of water, and when it has ceased to drop, add the liquid to that previously reserved, filter, and evaporate the filtrate to 8 J j fl. ounces. This contains about 10 per cent, of real acid, and is used mainly in combination with syrups or solutions of hypophosphites. It may, however, be prescribed in doses of ^ to I fl. drachm. 35. Acidum Lacticum. Lactic Acid. This acid is found in sour milk and is generally called "con- centrated lactic acid." It contains about 75 per cent, of real acid. It is produced by the fermentation of the milk sugar in the presence of casein, and is seldom prepared except by manufacturing chemists. It is used as a solvent for phosphate- salts, the products being termed, lacto-phosphates. In medicine it is used for diabetes, liver complaints, stomach troubles, etc. 36. Acidum Lacticum Dilutum. Diluted Lactic Acid. The new British Pharmacopoeia directs this to be prepared as follows : Lactic Acid, 3 fl. ounces. Distilled Water, sufficient to make . . 20 fl. ounces. Mix. This contains about 1 1.25 per cent, of real acid. The dose is ]/ 2 to 2 fl. drachms. 37. Acidum Nitricum. Nitric Acid. This is prepared by manufacturing chemists from nitrates and sulphuric acid. The acid directed in the United States Pharmacopoeia is what is commercially termed " C. P." nitric acid. The United States, British and French Pharmacopoeias direct a preparation containing about 70 per cent., while the German official acid contains only 30 per cent, of real acid. ACIDA — ACIDS. 38. Acidum Nitricum Dilutum, U. S. Diluted Nitric Acid. Nitric Acid I part or 1103 grains. Distilled Water, ... 6 parts or q. s. to make a pint. Mix, and preserve in glass-stoppered bottles. This contains 10 per cent, of real acid. The new British Pharmacopoeia directs a preparation containing 17.44 per cent, of real nitric acid. This is sometimes given as an acid tonic in doses of 20 to 40 minims. 39. Acidum Nitro-Hydrochloricum, U. S. Nitro-Hydrochloric Acid, 1880 — Nitro-Muriatic Acid, 1870. As the 1870 and 1880 United States preparations are so different, they are both presented. 1870. 1880. Nitric Acid, by weight, . . 3 ounces, 1% ounces. Hydrochloric Acid, by weight, 5 ounces, 5 ounces. Mix in a graduate of at least double the capacity of the preparation. This should be made several days before using to give the acids time to combine thoroughly. This is used as a solvent for gold, and medicinally as a tonic, in baths, the proportion for baths being from 1 to 4 fl. ounces to a gallon of water. 40. Acidum Nitro-Hydrochloricum Dilutum. Diluted Nitro-Hydrochloric Acid, 1880 — Diluted Nitro- Muriatic Acid, 1870. As the proportions of the 1870 and 1880 Pharmacopoeias are so different, we give them both. 1870. 1880. Nitric Acid 720 grains. 320 grains. Hydrochloric Acid, . . . 1200 grains. 1200 grains. Distilled Water, sufficient to make a pint. a pint. Mix the acids in a large graduate, and when clTcrvcscensc lias ceased add the water. 64 At IDA — ACIDS. The 1885 British Pharmacopoeia directs this acid to be made as follows : Nitric Acid, 3 fi. ounces. Hydrochloric Acid, 4 fi. ounces. Distilled Water 25 fl. ounces. Add the acids to the water and keep the mixture in a glass- stoppered bottle for 14 days before it is used. This very nearly corresponds with the U. S. 1870 formula. The dose of this acid is from 5 to 20 minims largely diluted. 41. Acidum Oleicum. Oleic Acid. This is the fatty acid with which alkalies and bases unite to form soaps or oleates. It is prepared by manufacturing chem- ists, by treating fats with superheated steam or by the saponi- fication of olein. It is used chiefly for making the class of galenicals called " Oleates," which see. 42. Acidum Phosphoricum. PJwspJwric Acid. The present United States officinal phosphoric acid is a liquid of the consistence of thin syrup (sp. gr., 1.347), contain- ing 50 per cent, of orthophosphoric acid. The 1885 British Pharmacopoeia has a similar, but more concentrated, preparation, which is called "concentrated phos- phoric acid." It contains 66.3 per cent, of real acid and has sp. gr. 1,500. The German officinal phosphoric acid contains only 20 per cent, of real acid, and has sp. gr. 1.120. The United States officinal preparation is very convenient, as it. can be diluted wfth four times its weight of distilled water for the officinal diluted phosphoric acid. This acid is seldom prepared by retail druggists, but may be readily made by those who wish, but as it is supplied at a fair price by manufacturing chemists it is hardly profitable to make it in a small way. It should be kept on hand for making dilute phosphoric acid extemporaneously in small quantities, as that spoils if long prepared. ACIDA — ACIDS. 65 Phosphoric acid is used mainly as a solvent for mineral phosphates, and for making diluted phosphoric acid. It is a nerve tonic and vitalizer. The dilute acid is usually prescribed. Glacial phosphoric acid is a solid, impure metaphosphoric acid, now but little used. A late process of making phosphoric acid by slow atmo- spheric oxidation has been proposed by Adolph Sommer, of California, and as it is of general interest to pharmacists, and may readily be employed by them, we repeat a portion of it here. The entire article was published in THE FORMULARY, January, 1886: NEW PROCESS FOR MAKING PHOSPHORIC ACID. Several forms of apparatus may be employed for making phos- phoric acid from phosphorus by atmospheric oxidation. Three of these forms are herewith described: I. A common tin can, with removable cover, is made perfectly water- tight by resoldering the seams. Through the center of the cover a hole is punched just large enough for the stem of a long ther- mometer to pass through, and three or four more holes, if not more than y% inch in diameter are made near the circumference of the cover. All around the inside of the can there is suspended by little hooks, which are formed by making incisions into the upper edge of the can, a piece of cloth reaching from the top to the bottom of the can. In the can is placed a glass jar which must be able to hold at least 3^4 times as much water by weight as there is P. to be oxidized. A funnel, amply large enough to hold the P., and wider than the jar, is placed upon the latter, and the funnel tube loosely closed by a piece of glass. [Instead of a glass jar and funnel a bottle may be used which has been cut in two at about three-fourths of its height. The upper and smaller portion of the bottle is inverted and placed into the lower portion, and answers the purpose of holding the P. quite well.] Four or five times as much water as the weight of the l\ is then poured into the space between the tin ran and tin- glass jar, and the whole apparatus filled with carbonic acid gas. When by the extinction of a burning taper, which is introduced into the upper portion of the can, it becomes evident that the atmospheric air has been entirely displaced, the sticks of P. are laid in the funnel, the thermometer bulb buried between the sticks of P., the cover put on the can, and all openings, save one, Closed by plugs. Through the open hole carbonic acid is passed into the apparatus lor a short time, in order to remove the air which has entered the apparatus during the introduction of the 1'. When 00 A.CIDA — ACI] >S. Fig. i. — /, funnel filled with P ; /, thermometer ; j, glass jar ; w, water ; /, cloth lining ; c, tin can. Fig. 2. — ■/, funnel filled with P ; /, thermometer ; j, glass jar ; w, water ; b, bottle (inverted) ; s, perforated stopper ; a, flower pot ; g, glass tube with opening on its side ; //, line of the cut. Fig. 4. — ■/, funnel filled with P ; /, thermometer ; j, glass jar ; w, water ; s, per- forated stopper ; a, flower pot ; g, bent glass tube ; c, tin pan. ACIDA — ACIDS. 67 this is considered accomplished, the last hole is closed, the apparatus put in a cool place, which is not. exposed to draught, and allowed to stand at rest for some time. When it is observed that the temperature within remains constant, one hole is opened and the apparatus left undisturbed for at least 24 hours. If the temperature within this time has not approached 35 ° C, another hole may be opened, and the same precautions observed as before. The number of holes that can thus be opened, before the critical temperature (above 35 ° C.) is reached, depends of course upon the temperature of the atmosphere surrounding the apparatus. If, at any time, from an excessive supply of air, or from an unusually high temperature of the atmosphere, the temperature of the P. should rise above 35 ° C. there is great danger that it will, as the writer has found to his sorrow in several instances, rapidly reach the melting point of P., which is 45 C. When this occurs and the P. melts it will naturally run into the receiver (the glass jar), and there, being screened from the action of the air by a covering of acid liquid, congeal into a solid cake. It then becomes necessary to take the apparatus apart, to remove the P. from the receiver, and to recommence the whole operation. After, however, the apparatus has once been regulated, it requires no further attention until the P. is entirely oxidized, which can be known by the thermometer indicating the same temperature within the apparatus as prevails without. It may seem desirable to have an explanation of some of the features adopted in this apparatus. The water in the apparatus was found necessary, because the ordinary atmospheric air does not contain sufficient moisture to dissolve the coating of oxides formed on the sticks of P. as rapidly as it is formed; but it was also found, that, unless by some means, the water was brought to the space above the P., the air entering the apparatus would not become moist sufficiently fast to produce the effect desired. A piece of cloth, lining the inside, and capable of drawing the water from the bottom to the top of the apparatus, suggested itself as the simplest means of effecting this purpose, and it does fulfill this function very satisfactorily. The reason for the adoption of several small holes instead of a single large opening, as a means of regulating the supply of air, is so evident that it needs no explanation. This style of apparatus is, however, not very durable, because of the slight, though perceptible, evaporation of the P., which causes a deposit of phosphoric acid to form on the inside of the tin can. This acid deposit slowly corrodes the tinned iron, and causes, after about three months of continuous operation, the formation of holes in the sides of the can. Through these holes an excessive amount of air is liable to enter the apparatus and cause the melting of the P. II. For the construction of a continuous and transparent oxidizing chamber a thick bottle, preferably one of white and very clear glass, 68 ACIDA — ACIDS. is selected, and the bottom very carefully cut off. (This cutting or cracking is best done by means of specially prepared carbon pencils made of powdered charcoal, saltpeter and tragacanth.) A common unglazed flower-pot, the largest that will go into the bottle, is inserted into the open bottle, so that the bottom of the flower-pot is directly over and in contact with the neck of the bottle. A funnel, the conical part of which is at least one inch shorter than the flower-pot, is then inserted in such a way that the funnel-tube passes through the bottom of the flower-pot and the neck of the bottle. Into the neck of the bottle the funnel-tube is securely fastened by means of a perforated rubber stopper or paraffined cork, which must be water-tight. Over the protruding end of the funnel- tube is fastened, by means of a bit of rubber tubing, a piece of glass tube, closed at one end and having a hole on one side. This closed tube is pushed so far over the funnel-tube that the opening in its side is a little above the end of the funnel-tube. This portion of the apparatus is then placed, neck downwards, over a large glass jar. Through the centre of the bottom, which was cut off the bottle, a hole of at least five-eighths of an inch in diameter is drilled. The bottom is then put into its original position on the bottle and fastened by glueing strips of paper over the joint. The hole which was drilled through the bottom is loosely closed by a paraffined cork, through which passes a thermometer. When the oxidizing chamber is thus completed, the cork is re- moved, and by means of a funnel, having a long bent tube, water poured into the space between the walls of the bottle and the flower- pot, until its level is within a short distance from the upper edge of the funnel within the flower-pot. A few Cubic-centimeters of water are also poured into the funnel until the water in the closed glass- tube, which is attached to the end of the funnel-tube, reaches a little over the end of the funnel-tube. Then a tube connected with a carbonic acid generator is inserted into the hole and carbonic acid gas passed into the oxidizing cham- ber. When the air within has been entirely displaced by the gas, sticks of P. are dropped through the hole into the funnel, until the latter is nearly filled. The thermometer and cork are then placed into position and the apparatus allowed to stand for a few hours. Then some notches are cut lengthwise into the cork and the appar- atus again left undisturbed for about 24 hours. If at the end of this time the temperature of the P. is below 35. ° C, a little more ventila- tion may be given by enlarging the notches in the cork. Whenever it is seen that the P. is nearly consumed or the water evaporated, a fresh supply is added through the hole without taking the apparatus apart. The flower-pot in this apparatus performs the same function as it fulfilled in the former (1), by the cloth lining, namely, that of absorb- ing the water and moistening the air. The closed glass tube which is attached to the funnel prevents the access of air from below to the P. in the oxidizing chamber. ACIDA — ACIDS. The acid that is formed runs down the funnel into the closed glass tube, and thence through the lateral opening into the glass jar, which serves as receiver. III. A still simpler form of a continuous oxidizing chamber I have constructed in the following manner : Through the bottom of a tin pan a hole of about one inch in diameter is cut, and a tube of tinned iron about half-inch long soldered into it. By means of a perforated cork a funnel is fastened into this hole so that the funnel-tube passes through the bottom, while the body of the funnel is inside of the tin pan. Into the end of the funnel-tube is inserted and fastened by a bit of rubber tubing a glass tube bent in a half circle. A common unglazed flower-pot is inverted over the body of the funnel and a paraffined cork with a thermometer inserted into the hole, which is in the bottom of the flower-pot. The whole apparatus is then placed over a glass jar and some water poured into the tin pan. The tin pan may advantageously be displaced by a wooden water bucket, whereby the apparatus becomes almost indestructible. After the pouring of a few drops of water into the funnel, whereby the bend of the glass tube is closed against a downward escape of gas, the apparatus is either filled with carbonic acid gas in the man- ner described under (2), or the oxygen is simply removed therefrom by burning P. in the interior. For this latter purpose a small iron deflagrating spoon, which will pass through the hole in the flower- pot, is employed. A bit of P. is laid into the spoon, ignited and quickly inserted into the flower-pot immediately closed by means of a cork. The apparatus is left undisturbed for a short time, until the air within has cooled to the normal temperature. The introduction of burning P. is then once more repeated, and after cooling the apparatus charged with P. through the hole in the flower-pot. The further manipulations and precautions are the same as have been given in the description of style (II). The rate at which the P. is oxidized by my method is a compara- tively slow one. In an apparatus of style I., in which the tempera- ture was kept on an average eleven degrees higher than that of the surrounding air, and the P., which was in the form of a solid cake of nearly five inches in diameter, exposed a surface of about 18 square inches, the P. was oxidized at the rate of about 10 Grains a day. The difference between the inner and outer temperature does not seem to be affected to any extent by an increase or decrease of the prevailing temperature; for nearly 200 observations which were taken at temperatures of the atmosphere ranging from 10 to 22 C, gave, while all other conditions remained equal, an almost constant ence. The arid which collects in the receivers has a specific gravity of [.48 to [.5, and is composed mainly of phosphorus and phosphoric .f ids in tin- proportion of 1 to 4, besides water. The exact 70 A.CIDA — ACIDS. composition differs with circumstances, and the determination of those circumstances may be the subject of some future paper. The further treatment of this acid is in every respect the same as has already been described under Prof. Wenzell's process ; but an acid prepared by my method has this great advantage over the one prepared by the former process, that it is already highly concentrated, and requires very little evaporation before the arsemous acid is reduced. 7 ■•. . , . , The oxidation of phosphorus acid to phosphoric acid by means op Bromine. Bromhydric acid by product. The product of the slow aerial oxidation of Phosphorus contains about i molecule of phosphorous acid to 4 molecules of phosphoric acid and besides these some impurities, such as arsenious acid and others mostly derived from the phosphorus. Of these impurities the arsenious acid is particularly objectionable and must be removed before the process of oxidizing is entered upon. The removal of the Arsenic as has been described in my article on " The manufacture of phosphoric acid from Phosphorus," is best effected by heating this acid to 190 C, subsequent diluting and filtering, after which the acid is readv to be oxidized. Heretofore nitric acid has been the only substance employed for this purpose, but since the price of Br has become so low (about 35c. per lb. in 5 lb. bottles) that it cost no longer is prohibitory to its employment in the industries, and furthermore since the value of hydrobromic acid has been recognized both in analytical chemistry as well as in therapeutics,— it may prove advantageous to substitute Br. for nitric acid in the oxidation of phosphorus to phosphoric acid. From the equation H 3 P0 3 + Br. 2 + H 2 0=H 3 P0 4 +2HBr. 82 159.5 18 98 161. 5. it will be seen that it requires nearly 2 parts of Br. to every 1 part of phosphorous acid. But the total acidity of the mixture of phosphor- ous and phosphoric acids, when of a sp. gr. of 1.48 is about 66 per cent the composition of which approximates the proportion of 1 molecule (or 12$ of H 3 P0 3 to 4 molecules (or 54^) H 3 P0 4 . To convert the 12 per cent, of phosphorous acid into phosphoric acid would require theoretically 2x12 = 24 per cent, of Br. This result agrees very closely with that obtained in practice where it was found that with an acid of a sp. gr. of about 1.48 there was needed a httle over one-fourth of its weight of Br. to complete its oxidation. This operation may be performed, after the Arsenic has been removed, either in a bottle containing the acid and Br. by shaking this mixture from time to time (it must however not be shaken too often nor too much at one time, since a considerable amount of heat is liberated by the reaction, which may easily reach the boiling point of Br.— 65 C), or it may be accomplished more rapidly by pouring the two substances into a retort and keeping the mixture agitated by slowly passing air through. ACIDS. 71 In order to prevent any Br. vapor, which is carried off by the air, from contaminating the atmosphere of the laboratory, I caused the air, which escaped from the retort, to pass through two bottles con- taining a solution of caustic potash. When the mixture is no longer decolorized on standing for about 24 hours, but retains a permanent orange color, which is due to an access of Br., the oxidation may be considered completed. The excess of Br., is best removed by the addition of a small portion of the unoxidized mixture of acids, which has been reserved for this purpose. A still better plan by which the liability of introducing a large ex- cess of Br. into the acid is avoided, but which requires a little longer time than the one related last, consists in pouring the acid to be oxidized into a large wide-mouth glass-stoppered bottle and the Br. into another but smaller glass-stoppered bottle, which will go into the larger one. After the open bottle with Br. has been inserted into the bottle with acids and the latter closed, the Br. gradually evapor- ates and oxidizes through its vapor, which is absorbed by the acids, the phosphorous to phosphoric acid. When the interior temperature of the apparatus is kept below 25. C. the acids do not consume the Br. as rapidly as it evaporates and therefore are under these condi- tions always : dark-orange colored, unless the supply of Br. vapor is shut off by closing the Br. bottle, whereupon the color of the acids disappears within 24 hours. But when the apparatus is kept in a moderately warm place, where the temperature is 25 ° C. or over, the reducing power of the phos- phorous acid is so much increased that the mixture of acids remains colorless, or acquires only a light orange color so long as any phos- phorous acid is left unoxidized. But as soon as this acid has disap- peared, the liquid assumes a dark orange color, when the bottle with Br. is to be lifted out, closed and kept for the next operation. There remains then only the separation of the bromhydric acid from the phosphoric acid, which is accomplished by distillation in a retort from an oil bath. The precautions which have been pointed out in a previous article on the manufacture of bromhydric acid in regard to its liability to decomposition by organic substances, have to be observed here. The mere insertion of the neck of the retort into a well-cooled receiver is sufficient. Neither luting nor rubber connections are necessary. The first portion which comes over con- sists principally of water (and Br., if this has not been removed in the manner stated above), and should be withdrawn, before the bromhydric acid, which does not evaporate to any great extent until a temperature of about 125 C. has been reached, begins to distill. The distillation is continued until a temperature of about 180 C. is reached, when the lire is extinguished and the receiver with brom- hydric acid detached. The retort and its contents are allowed to stand till cold, when a quantity of water equal to about one-third of the bulk of the contents is poured into the retort. Heat is then again applied and the distillation continued until the temperature within the retort has reached the same height as before. This second 72 A( IDA— ACIDS. distillation serves to remove a portion of bromhydric acid, which cannot be removed in the first distillation. The phosphoric acid, which forms the residue in the retort, is a black syrupy liquid, which, however, after dilution with water, diges- tion with about one-half per cent, of purified animal charcoal and subsequent filtration through white filtering paper (best, the brand known as "Chlorine paper") becomes perfectly colorless. The black color of the phosphoric acid is due to an organic im- purity of the commercial Br., which, it is said, is derived from the luting of the stills, in the composition of which tar is used. The bromhydric acid which has distilled over, requires to be redis- tilled before it can be considered sufficiently pure for pharmaceutical purposes. If the addition of Br. is made to an acid, from which the arsenic has not been removed, the entire amount of arsenic will distill over with the bromhydric acid, while the phosphoric acid will be found free from arsenic. 43. Acidum Phosphoricum Dilutum. Diluted Phosphoric Acid. The United States 1880 formula is as follows: Phosphoric Acid (50 per cent.), 2 parts or 1541 grains. Distilled Water, . . 8 parts or q. s. to make a pint. Mix, and keep in a cool place. This contains 10 per cent, of real acid. The 1885 British Pharmacopoeia directs Concentrated Phosphoric Acid, Br. P., . 3 fl. ounces. Distilled Water, sufficient to make, . 20 fl. ounces. Mix. This contains 13.8 per cent, of real acid H. ? P0 4 , or 10 pet- cent, of phosphoric anhydride P 2 5 . Diluted phosphoric acid is much used as an invigorator and vitalizer for nervous debility, sexual weakness, etc. The dose is from 10 to 30 minims or more. " Acid phosphate" is a solution of mineral phosphates in phosphoric or diluted phosphoric acid. See Solutions and Standard Remedies. ACIDA — ACIDS. 73 ( 44. Acidum Sulphuricum. Sulphuric Acid. The C. P. sulphuric acid of commerce corresponds to the requirements of the Pharmacopoeias which direct it to contain 96 to 98 per cent, of real acid H 2 S0 4 . It is prepared by manufacturing chemists. Haller's Acid Drops {Acidus Liquor Halleri) is a mixture of equal weights of sulphuric acid and alcohol. They should be mixed by adding the acid slowly and gradually to the alcohol. 45. Acidum Sulphuricum Aromaticum. Aromatic Sulphuric Acid. [Elixir of Vitriol.) Although this preparation more properly belongs among the tinctures it is classed by the pharmacopoeias with the acids, and, is, therefore, given here. The United States 1870 formula contained about 14 per cent, of acid (1305 grains), and was made aromatic by ginger (203 grains), and cinnamon (327 grains) in powder, with alco- hol enough to make a pint. The 1880 formula directs about 20 per cent, of acid, and substitutes tincture of ginger and oil of cinnamon for the powders. 1 [ere is the formula : Sulphuric Acid, by weight, .... 1392 grains. Tincture of Ginger, 378 minims. Oil of Cinnamon 7 minims. Alcohol, sufficient to make a pint. Add the acid slowly to 8 ounces of alcohol, then add the tincture and oil and enough alcohol to make the measure a pint. The [885 British formula contains only 12.5 per cent, of real acid. It is composed of 1 II. ounce each, strong tincture of ginger and spirit of cinnamon, 1 ■_. fl.ounce sulphuric acid, and [8 fl. ounces of rectified spirit. 74 ACIDA — ACIDS. Aromatic sulphuric acid is an acid tonic and astringent used for hemorrhage, night sweats, etc. The dose of the United States preparation is from 5 to 20 minims diluted with water. 46. Acidum Sulphuricum Dilutum. Diluted Sulphuric Acid. The United States officinal preparation is as follows: Sulphuric Acid, . 1 part or 779 grains. Distilled Water, . . 9 parts or q. s. to make a pint. Mix, by adding the acid gradually to the water. This con- tains 10 per cent, of real acid. The British 1885 officinal formula directs Sulphuric Acid, !350 grains. Distilled Water, sufficient to make 20 fi. ounces, Imperial. Mix, by adding the acid gradually to the water. This con- tains 13.65 per cent, of real acid, being about a third stronger than the United States preparation. The German officinal is 1 part acid to 5 of water. Diluted sulphuric acid is the most used of any of the dilute acids. It is employed as an acid tonic and a solvent for quinine and other salts. The dose is from 5 to 40 minims, in water. 47. Acidum Sulphurosum. Sulphurous Acid. The United States preparation is made by adding Sulphuric Acid, 7 parts. To Charcoal, 1 part. And distilling into Distilled Water, ... 50 parts. Until the water has absorbed 3^ per cent, of sulphurous acid gas. The 1885 British formula directs the preparation to contain 6.4 per cent, of real sulphurous acid H 2 S0 3 . ADEPS — LARD. 75 It is used externally in some forms of skin diseases, and internally as a germicide in zymotic diseases, etc. The dose is from x / 2 to I fl. drachm. 48. Acidum Valerianicum. Valerianic Acid. This is prepared from valerian, or artificially from fousel oil and chromic acid, and is chiefly used for making: valerianates. ADEPS — LARD. The name lard is applied commercially to the rendered fat of the hog, Sits scrofa. In pharmacy the term is intended to apply only to lard purified by washing with water, melting and straining. The U. S. Pharmacopoeia designates this simply by the name adeps, or lard, but the Br. Ph. more properly terms it adeps prceparatus, or prepared lard. Since the introduction of Petrolatum and Lanolin the use of lard as an ointment base has very much decreased, and much controversy has arisen as to which is the most valuable for this purpose. It has been shown that, although petrola- tum ointments do not become rancid, they arc not so readily absorbed as those made with lard, and that the reactions which are desired in some of them do not take place when petrolatum is substituted for lard. Lard is still retained as the ointment-base of the pharmacopoeias, but will no doubt be gradually replaced by some more suitable vehicle. The medicinal preparations in which lard is used will be found under the headings Cerata, Unguenta, etc. 49. Adeps Prasparatus. Prepared Lard- - Washed Lard. The usual method of washing lard is to spread it on a stone or earthenware slab, and allow a small stream of water to trickle over it, at the same time working it well with .1 spatula or other convenient mixer. Altera thorough washing in this way it is melted and strained. ADEPS — LARD. We suggest the following method, which will be found more convenient and will secure better results : Melt the lard and pour it into any convenient bottle that will hold three times the quantity desired to be washed. Fill the bottle nearly full of hot water, and while the mixture is cooling agitate it frequently ; by this means the lard is granu- lated or reduced to small fragments. When cool, pour off the water and add fresh cold water to the granulated lard ; agitate, pour off the water, add fresh cold water again, and so con- tinue until the lard is thoroughly washed, when it may be melted by water-bath and strained into earthen pots. By add- ing a fl. drachm of Tincture of Benzoin to each pound of the lard when melted previous to straining it will keep unchanged. Prepared lard is used for making benzoinated lard, simple cerate, simple ointment and some other cerates and oint- ments, therefore it may be said to be the base of the officinal ointments and cerates. It is to be regretted, however, that it is so seldom used when directed, the majority of druggists, either through ignorance or neglect, using unwashed lard instead and then wondering why their ointments so soon become rancid. Besides its use in medicinal preparations, washed lard is extensively employed in Continental Europe, for absorbing the odors of flowers. Flower "pomades" are made by spreading layers of flowers on a thin stratum of washed lard, and renewing them as often as the odor of the flowers is well absorbed. From 24 to 30 layers of flowers are thus used before the washed lard is thoroughly saturated with the perfume. The process is called enfleurage, and the pomades made by the process are known as No. 24 or No. 30 pomades — the numbers indicating the number of times fresh flowers have been supplied to the lard during the process. 50. Adeps Benzoinatus. Benzoinated Lard— Benzoinated Ointment. Benzoin, in coarse powder, . 2 parts or 140 grains. Prepared Lard, 100 parts or 1 pound. Melt the lard by heat not exceeding 140 F., add the benzoin and macerate with frequent stirring for two hours, .ETHERA — ETHERS. 77 then strain to remove the particles of benzoin. This will keep unchanged for any length of time, and is therefore mainly used as an ointment base, and for general pharmaceutical purposes when lard is desired. The odorous balsam of the benzoin is dissolved by the lard, and acts as a preservative. The 1870 U. S. P. directed tincture of benzoin to be used instead of the powder, but it has been found objectionable because of the irritation which is produced when the lard thus prepared is applied. ETHERA — ETHERS. Ethers are volatile liquids, which, from their property of rapid evaporation have derived their name Ether (air). They are chemically oxides of alcohol radicals, made by mixing- acids with alcohols, etc., and distilling over the lighter portions. They are mostly inflammable, and of low specific gravity. The name EtJicr is applied in pharmacy only to the variety known commercially as sulphuric ether, and chemically as ethyl oxide ; other ethers are known commercially by the names of the acids with which the alcohol radical is combined, as acetic ether, nitrous ether, or chemically by the names of the acid and alcohol radical, as amyl acetate, ethyl nitrite, etc. Some substances are termed ethers which are not properly so classed, as petroleum ethers, while others which are properly ethers do not bear the name, as nitrite of amyl, etc. Ethers require conveniences for making not generally at hand except in chemical laboratories, and are therefore usually supplied by manufacturing chemists. The ethers chiefly used in pharmacy are derived from the amy] and ethyl radicals. The amy] ethers are mainly used for making artificial fruit and liquor flavors; and the ethyl ethers are chiefly used in medicine. Besides these, ethers are made from Methyl, Propyl, Butyl, Caproyl, and some other alcohol radicals. They are chiefly used in making artificial fruit flavors. Nearly all acids ma)- be combined with these radicals to form ethers, the combination being the same chem- ically as when acids unite with other bases to form salts. .ETHERA — ETHERS. except that the ethers are always gaseous or liquid, and are separated by distillation. Under this heading will be considered the preparations which are official or well known commercially as ethers, and a few ethereal preparations not otherwise classified ; other ethereal preparations will be mentioned under the headings in which they properly belong. Ethyl Ethers. — Various acids combine with ordinary i Ethyl) Alcohol (C 2 H 5 HO) to form a variety of Ethers. Sev- eral of these are used in medicine and in making medicinal preparations; while some of them are used to prepare artificial fruit and liquor flavors. The following list includes most of the Ethyl Ethers that are used. They are known commercially as Ethers : Ethyl Acetate C,H 5 C 2 H 8 2 Acetic Ether. Ethyl Benzoate C 2 H 5 C~H 5 Benzoic Ether. Ethyl Bromide CoH 5 Br. Hydrobromic Ether. Ethyl Butyrate C.,H 3 C 4 H 7 0.> Butyric Ether. Ethyl Chloride C 2 H 5 C1. Hydrochloric Ether. Ethyl Formiate C s H 5 CH0 2 Formic Ether. Ethvl Todide "CoH 3 I Hydriodic Ether. Ethyl Nitrite C s H 5 NO s Nitrous Ether. Ethyl Oxide (C.,H,) 2 Sulphuric Ether. Ethyl Pelargonate C 8 H 5 C 9 H 17 O s Pelargonic Ether. Ethvl (Enanthvlate C,H 5 C 7 H 13 2 CEnanthic Ether. Ethyl Sebacate' C 2 H 5 C 10 H 16 O 5 Sebacic Eth er. Of the foregoing Butyric Ether resembles pineapple in flavor, and is often called Pineapple Oil. OEnanthic Ether resembles the greengage or plum in flavor, Pelargonic Ether the quince, and Sebacic Ether the melon. 51. either. Ether—Sulphuric Ether— Ethyl Oxide. (QH 5 ) 2 0. This is prepared by mixing sulphuric acid and alcohol grad- ually in a retort, distilling over the lighter portions, and puri- fying the distillate by shaking with a solution of chloride of calcium and slacked lime. The U. S. P. describes under the name of Ether a liquid composed of 74 per cent, of ethyl oxide and 26 per cent, of alcohol, containing a little water, sp. gr. 0.750, and under the ETHERS. 79 name of Stronger Ether, a liquid containing 94 per cent, of ethyl oxide and 6 per cent, of alcohol, sp. gr. 0.725. The former is known commercially as sulphuric ether or common ether, while the latter is known as concentrated ether. The 1 885 Br. P. ether contains 92 per cent, of ethyl oxide, which nearly corresponds with the U. S. stronger ether. .Esther Fortier. — Stronger Ether is used in medicine as an anaesthetic, by inhalation, and locally in the form of spray for the same purpose ; and is given internally, much diluted or combined with other medicines, as an anodyne. It is used in pharmacy for making collodion, oleo-resins, tinctures and other galenicals. Common ether is generally used externally. The dose of stronger ether when administered internally is from 20 to 60 minims, largely diluted. Purified Ether.— Manufacturing chemists furnish under this name a pure ether for anaesthetic use. The 1885 Br. P. directs such a preparation, calling it yEther Punts. It is simply pure oxide of ethyl (C 2 H 5 ) 2 0, free from alcohol and water. Washed Ether is a commercial term for Ether of about 0.735 specific gravity, used in the arts. It is also called Letheon. 52. ^ther Aceticus. Acetic Ether — Acetate of Ethyl— Ethyl Acetate. GHoQHA. This is prepared by mixing sulphuric acid and alcohol grad- ually, adding acetate of sodium and distilling, then shaking the distillate with carbonate of potassium and redistilling. Its specific gravity is from 0.889 to 0.897. It is used as a flavor- ing ingredient in medicinal preparations, and is considerably employed in making artificial fruit flavors. 53. ^ther Hydrobromicus. Hydrobromic Ether- Ethyl Bromide. C,II,Br. This ether is made from bromine and alcohol by the aid of phosphorus, distillation and purification. 80 .KTHKKOLES OR ETHERATES. It has been somewhat used as an anaesthetic in place of chloroform, but its use has not yet become general. Its action is said to be more rapid and less disagreeable than chloroform. 54. JEther Hydrochloricus. Chloric Ether — Spirit of Chloroform. Chloride of Ethyl was formerly prescribed under the name of Chloric or Hydrochloric Ether, but has now been supplanted in practice by Spirit of Chloroform, which is made by dissolv- ing one part of Chloroform in nine parts of Alcohol. A sim- ilar preparation was formerly sold under the name of Dutch Liquid. It consisted of Bichloride of Ethylene, which is iso- meric with Chloride of Ethyl. 55. ^Ether Nitrosus. Nitrous Ether— Nitrite of Ethyl— Ethyl Nitrite. QH 5 N0 2 . Preparations bearing the name of Concentrated Nitrous Ether and other similar titles, have of late been extensively adver- tised and sold for the purpose of making Spirit of Nitrous Ether. This ether is the same that is formed in the official process of making Spirit of Nitrous Ether (which see) before the alcohol is added. In this form it has only recently become an article of commerce. It is extremely volatile, and requires to be carefully handled to prevent accident. To make Spirit of Nitrous Ether it has only to be mixed with 19 times its weight of alcohol. iETHEROLES OR ETHERATES. These are simply solutions of various medicinal substances in Ether, the same as Alcoholes or Spirits are solutions of medicinal substances in Alcohol. They are officinal in the French text-books, and are not infrequently prescribed or called for in this country. For other etherial preparations see Collodion, Oleo-resin, Etherial Tinctures, etc. ^THEROLES OR ETHERATES. 81 56. Etherate of Ammonia. Water of Ammonia, 22 , by weight, . . . 1 part. Stronger Ether, by weight, 1 part. Mix. This is used as an application for rheumatism, neuralgia, headache, etc. 57. Etherate of Camphor. Camphor, by weight, 1 part. Ether (76 per cent.), by weight 9 parts. Dissolve the Camphor in the Ether. This is used as an application for toothache, headache, pain, swelling, etc., and as an anti-spasmodic for convulsions, croup, etc. A saturated solution of Camphor in Ether is also used. 58. Etherate of Cantharides. Cantharides, in fine powder, 1 part. Ether, 2 parts. Mix together and set in a warm place, in a closely-stopped bottle, for 7 days, agitating daily; then pour off the liquid and press the drugs as rapidly as possible to avoid evaporation This is used as a vesicant, but has been mostly superseded by Cantharidal Collodion, which see. 59. Etherate of Chloride of Zinc. Chloride of Zinc, by weight, 15 parts. Stronger Ether, by weight, 60 parts. Absolute Alcohol, by weight, 30 parts. Mix and decant after standing a few hours. This is given as an anti-spasmodic, in doses of 2 to 4 drops, administered in syrup. 82 /ETHEROLES OR ETHERATES. 60. Etherate of Phosphorus. Phosphorus 1 part. Spirit or Essence of Peppermint, ... 12 parts. Stronger Ether 150 parts. Put the Phosphorus with the Essence in a small bottle tightly stopped and warm by water-bath until the phosphorus is melted, agitate constantly while cooling, to divide the phos- phorus, then add the Ether and allow to macerate for several days with frequent agitation. This is similar to several tinc- tures and solutions of Phosphorus, and may be used whenever Phosphorus in a free state is indicated. Dose, 2 minims, on sugar. Two minims represent about -^ grain of Phosphorus. The above is the formula of Lcebelius. Another Ether of Phosphorus is sometimes used, but is an unsafe remedy on account of its strength. It is as follows: Phosphorus, 1 part. Stronger Ether, 50 parts. Macerate with frequent agitation in a small well-stopped bottle for 30 days. 61. Etherate of Sulphur. Washed Sulphur, 1 part. Stronger Ether, 10 parts. Mix, and macerate with frequent agitation for 30 days. This is given in doses of 2 to 5 minims as a preventive and cure for cholera and other zymotic and septic diseases. 62. ^therum Oleum, U. S. Etherial Oil— Heavy Oil of 11 'inc. " A volatile liquid consisting of equal volumes of Heavy Oil of Wine and Stronger Ether." Alcohol, by weight, 24 parts. Sulphuric Acid, by weight 54 parts. Distilled Water, by weight, 1 part. Stronger Ether, by weight, a sufficient quantity. ALBUMEN. . 83 As this is seldom made by druggists we do not repeat the directions for making here, but refer to the U. S. P., page 232. It is generally made and supplied by manufacturing chemists, and is used in medicine only in the preparation of Spiritus yEtheris Compositus, or Hoffman's Anodyne. 63. ^thyleni Bichloridum — Bichloride of Ethyline — (Dutch Liquid). This liquid was discovered by Holland chemists in 1795, and was used for a long time as an anodyne and anaesthetic until superseded by ether and chloroform. It is still much called for among the Holland Dutch. Its chemical formula is C 2 H 4 C1 2 . It is used by inhalation, the same as ether, or mixed with twice its weight of alcohol, making a preparation similar to Hoffman's Anodyne, and given in doses of from 10 to 30 minims. ALBUMEN. The most common and familiar form of Albumen is the white of egg {Albumen Ovi), which is freshly obtained from hen's eggs, or may be had in the market dried in scales or granulated. Another variety is obtained from blood and other animal fluids, and still another is found in the juices and seeds of plants. White of Egg is the only form of Albumen used in phar- macy. It is also considerably used in the arts for various pur- poses, as calico printing, making photographic paper, etc. In pharmaceutical preparations the natural white of egg, which contains about 12 y> per cent, of Albumen, is generally used, but dried-egg albumen is sometimes employed. The chemical composition of Albumen has not yet been definitely ascertained. It is the Sphynx of the chemist, and its formula is still written with an interrogation point 1?). It has been found, however, to contain Sodium, Sulphur, Nitro- 84 ALCOHOLES — ALCOHOLS. gen, Hydrogen and (white of egg) about 85 per cent, of water. Gerhardt has given its approximate formula as HNaC 72 H 110 N 18 SO 22 ,H 2 O. Albumen is but little used in medicinal preparations, but might be more frequently employed with advantage. It forms insoluble compounds with salts of mercury, lead and copper, and some other poisonous substances, and is therefore given in large doses in cases of poisoning by these substances. It forms insoluble compounds with tannin and other vegetable astringents, and maybe employed with advantage to detannate preparations which it is desirable to combine with iron, etc., as Elixir of Calisaya, etc. It is a valuable nutritive, and is given combined with iron, soda and glycerin in the form of a syrup. (See Syrup Albuminate of Iron.) Its property of coagulating by heat makes it useful for clarifying liquids, syrups, etc. It is used externally in some toilet preparations and liniments, and in many forms combined with wines, etc., as a nutritive drink for invalids. The combinations of Albumen with medicines are frequently called nitrogenized medicines ox protein compounds. Albumenoids are substances resembling Albumen in their general character and composition. Fibrin is the chief con- stituent of muscular tissue and is found in solution in the blood. Casein is a constituent of milk, and Legumin (called vegetable Casein) of leguminous seeds, beans, peas, almonds, etc. Albuminates are chemical compounds, either soluble or insoluble, of Albumen with other substances. The compounds and mixtures generally used will be found under the headings Glycerites, Syrups, Solutions, etc. ALCOHOLES— ALCOHOLS. The general name AlcoJwl is applied to a class of substances which are, chemically, hydrates of a series of Alcohol radicals. In pharmacy, Alcohol \s the hydrate of Ethyl, and is obtained ALCOHOLES — ALCOHOLS. 85 by distillation from fermented grains or other substances which contain starch or sugar. Alcohol Radicals and Primary Alcohols. — In chemistry, the Alcohol radicals constitute a homologous series which increases by CH 2 (one atom of carbon to two of hydrogen). This is known as the C„H 2 « +1 series (n equaling any number). Starting with hydrogen as a base, the radicals are built up by the successive additions of CH,. ALCOHOL RADICALS. [Hydrogen HJ Methyl CH 8 Ethvl C 2 H 5 Propyl (or Trityl) C 3 H 7 Butyl (or Tetry'l) C 4 H 9 Amyl C 3 H 1X Caproyl (or Hexyl) C 6 H lg (Lnanthyl (or Heptyl) C 7 H 15 Capryl(or Octyl) C 8 H 17 Nonyl C 9 H 19 PRIMARY ALCOHOLS. Methyl (or Wood Alcohol). .CH s HO Ethyl (or common Alcohol) C»H 5 HO Propyl Alcohol C~H 7 HO Butyl Alcohol C 4 H 9 HO Amyl Alcohol C 3 H u HO Hexyl Alcohol C 6 H 13 HO Heptyl Alcohol C 7 H 15 HO Octyl Alcohol C 8 H 17 HO Nonyl Alcohol C 9 H 19 HO The foregoing Alcohols are all liquids, their specific gravity increasing with their molecular weight. To these may be added Cetyl Alcohol (C 16 H 33 HO), Ceryl Alcohol (C 37 H 55 HO) and Melissyl Alcohol (C 30 H C 1 HO), which are white crystal- line solids. Alcohol radicals are gaseous in their free state. They form hydrides (which are mostly gaseous) with hydrogen ; oxides or ethers (mostly liquid; with oxygen ; hydrates with hydrogen and oxygen ; aldehyds by the loss of hydrogen ; and acids by combining one equivalent of oxygen with the aldehyds. The following table shows the changes that occur: RADICALS I FREKi. Hydrides. (EthenO Methyl Mil.,) ('11,11 Ethyl (< ,11 ... , C 8 H 8 H Propyl « ..II- I < .11-11 Butyl ((,11,1.. <',H„ 1 1 Amyl (C-,11,,1-. ■• < ',H, ,11 Caproyl M', ; l !,,>,.. C 8 H 18 H l ti Etc. (CH 8 ) s O en, no (C 8 H 8 ) 8 C E H B HO Hydrates (Alcohols) (I M ,...'- (C B B o (C 6 H 18 ) 8 Etc. c.,11 no ( Jljlo C 5 H,,HO C 6 H 18 HO Etc. Aldehyds (II.,0 C.,H,0 C 8 H 6 c,ll,ii C B H 10 O C 8 H 18 Etc. Acids. Cll.,0„ C.,11 ,M„ ('., II, ( )., < ,II s O„ C B H 10 O 8 C 8 H 18 £ Etc. Besides the above-mentioned primary Alcohols, many other substances, which have the same elements in different combi- nations, arc grouped with Alcohols, as Glycerin or Glyceric 86 \.LCOHOLES — ALCOHOLS. Alcohol (C 3 H s (H0 3 ), the Alcohols of the phenol series of which* carbolic acid is a well-known member, and many other less familiar substances. Commercially, only two kinds of Alcohol are known in this country, namely, grain Alcohol (Ethyl Alcohol), which is known simply by the name "Alcohol," and wood Alcohol (Methyl Alcohol), which is usually known by that name, but is also sold under the proprietary title Alcoline. Methylated Spirit is sold in Great Britain for manufacturing purposes, without tax. It is composed of 9 parts of alcohol and 1 part of wood alcohol, making it unfit for use as a beverage. In the U. S. and German Pharmacopoeias Alcohol (Ethyl Alcohol) only is mentioned. The 1885 Br. P. recognizes Amyl Alcohol and Ethyl Alcohol ; but, commercially, Amyl Alcohol is known as fusel ox f ousel oil. 64. Alcohol. Ethyl Alcohol— Ethyl Hydrate. C 2 H 5 HO. The present U. S. P. describes Alcohol as " a liquid com- posed of 91 per cent, by weight (94 per cent, by volume) of Ethyl Alcohol, and 9 per cent, by weight (6 per cent, by volume) of water, sp. gr. 0.820 at 15. 6° C. (60 ° F. )" It boils at 78 C. (172.4 F.). The commercial Alcohol (188 proof), which is furnished by the distillers in this country, corresponds very closely with this description. The U. S. P. designates it simply by the name "ALCOHOL," while the Br. P. terms it ALCOHOL ETHYLICUM — Ethylic Al- cohol, which seems the more proper name, as it distinguishes it from other Alcohols. Alcohol is chemically Hydrate of Ethyl. It is composed of Carbon, 52.67 parts, by weight. Hydrogen, 12.90 parts, by weight. Oxygen, 34-43 parts, by weight. 100. It is obtained by distillation from fermented grain, fruit or other substances composed largely of starch or sugar. In this ALCOHOLES — ALCOHOLS. 87 country Alcohol is principally made from common whisky, by redistillation. When grain is used for making Alcohol or spirits a portion of it is malted for the purpose of developing the diastase. The coarsely-ground unmalted grain is then scalded to soften the starchy matter, the malt is added, which converts the starch, first, into dextrin, and then into saccharine matter. It is then cooled, yeast is added, and the vinous fer- mentation begins, converting the saccharine matter into Alco- hol and liberating carbonic acid gas. When fermentation has proceeded long enough the mash is put into stills, and the Alcohol in a weak form (whisky) is obtained. It is then redis- tilled to obtain the Alcohol of commerce. When Alcohol is made from fruit or saccharine matter the process begins with the vinous fermentation. Alcohol is the spirit or " spirits " present in wines, beer, cider and all still malt and distilled liquors ; its varying proportion determines the strength of the liquors. Absolute Alcohol is Alcohol containing not more than one or two per cent, of water. It is made from ordinary Alcohol by agitating with carbonate of potassium and fused chloride of calcium, or with slacked lime (which absorbs the water) and redistilling. Its sp. gr. is 0.794 to 0.800. It is sometimes called Attwood's Patent Alcohol. Stronger Alcohol. — This was directed in the U. S., 1870, Pharmacopoeia, but was not retained in the later revision. Its sp. gr. was 0.817, and it was stronger than the commercial Alcohol, so it was very properly deleted. Rectified Spirit — Spiritus Rectificatus—Br. P.— u Alcohol, with sixteen per cent, of water, obtained by the distillation of fermented saccharine fluids.'' This is the Alcohol chiefly directed to be used in the prepara- tions of the Br. P. It corresponds very nearly with the 1870 U.S. official Alcohol its sp. gr. is 0.838, while the sp. gr. of the 1870 U. S. Alcohol was O.835 and contained 15 percent, of water. To convert the U. S. [880 or commercial Alcohol into recti- fied spirit of the British standard, add 1 fluidounce of water to i" fl. ounces of Alcohol. This should be observed when work- in.; formulae of the Br. P. 88 ALCOHOLES — ALCOHOLS. The abbreviation S. V. R., Spiritus I T ini Rectificatus, so fre- quently met with in English formulas, refers to rectified spirit, which was formerly called Rectified Spirit of Wine. Spiritus — Wcingist. P. G. — The Alcohol of the German Pharmacopoeia contains 85.6 to 87.2 per cent, of absolute Alco- hol and has sp. gr. 0.830 to 0.834. It is, therefore, a trifle stronger than rectified spirit. Cologne Spirit. — In this country this is deodorized Alcohol, of the same proof as official Alcohol. In France, Cologne spirit is distilled from grapes, and is of about the same proof as Alcohol. When this is desired it is usually called French Cologne spirit. The high duty prevents its use to any extent in this country. Pure Spirit is a commercial name for deodorized spirit of about 100° proof, which corresponds very nearly with diluted Alcohol. It is similar to but only about half the alcoholic strength of Cologne spirit, and is largely used by rectifiers of liquors and manufacturers of wines for mixing. It is also called neutral spirit. Spirit of Wine is a commercial name for Alcohol, although it properly applies to the French Cologne spirit. It is fre- quently called for in old recipes, and Alcohol should be dispensed. High Wine is a name used by distillers for low-proof Alco- hol. When called for, ordinary Alcohol may be used. Proof of Alcohol. — In this country liquors which contain one half, or 50 per cent., by measure of absolute Alcohol are called PROOF, or ioo°. If they contain more than that they are called above or over proof, and, if less, below proof, the proof being shown by adding to or subtracting from 100; thus, whisky, gin, rum and brandy are generally proof, or ioo . If five over proof, they would be called five above or over proof, or 105 , and, if ten less than proof, ten below proof, or 90 . Commercial Alcohol is 188 , or 88° over proof, or 94 per cent, (the percentage of Alcohol by measure always being one half the proof degrees). To reduce official or commercial Alcohol to any desired per- centage of Alcohol, divide its per cent. (91) by the percentage ALCOHOLES — ALCOHOLS. 89 required, and subtract I from the quotient. This gives the number of parts, by weight, of water to be added to one part, by weight, of Alcohol. If volume per cent, is required, divide the volume per cent, of official Alcohol (94) by the required percentage by volume and subtract 1 from the quotient. For example, supposing 75 per cent. Alcohol, by weight, is required : 75)91(1.21 75 160 150 100 75 Subtract 1 from the quotient. 1. 21 1 .21 about |- of water, or 1 ounce to by weight, to be added. Relation of Weight to Volume. — The change in the U. S. P. of 1880 to parts by weight, instead of fluid measure, makes it necessary to thoroughly understand the relation between the weight and measure of Alcohol. It is clearly shown in the following tables : TABLE OF MEASURE, WITH WEIGHT EQUIVALENTS OF ALCOHOL, SP. GR. 0.820 AT 15.6 C. (6o° F.).* FLUID MEASURE. In Troy Grains. American (Apothecary). Fluid Measure. 1 Minim weighs : 0.78 1 Fluiddrachm weighs i 46.7 1 Fluidounce weighs 373-7 1 Pint (16 fl. ounces) weighs 5978. S British (Imperial). Fluid Measure. 1 Minim weighs O.75 drachm weighs 44.8 1 Fluidounce weighs 358. 1 Pint (20 fl. ounces) weighs 7 I 75-° Metric Fluid Measure. 1 Cubic centimetre weighs 12.4 I Litre weighs I2455.O In Troy Ounces. O.0OI6 O.O97 0.779 12.462 O.OOI5 O.O93 O.748 f4.943 O.026 25-949 In Avoir. In Metric Ounces. Grammes. O.OOI8 O.IO7 O.S54 t3-674 O.0505 3.029 24.230 387. 6SO O.OOI7 O.0484 O.I02 2.908 O.820 I 23.246 16 400 4^4-937 0.028 ! 0.807 28.554 S07.126 hoi increases or decreases in volume, about -fj^ for each Fahrenheit of temperature between 50 and 75 . 90 ALCOHOLES — ALCOHOLS. TABLE OF WEIGHT, WITH MEASURE EQUIVALENTS OF ALCOHOL, SP. GR. 0.820 AT 15.6* C. (60 F.). American In Ameri- (Apotheca can Minims, ry l Fluid- Ounces. Apothecary Weight. 1 drain measures 1 Drachm measures 1 Ounce (troy) measures British Metric 1 Imperial) Cubic Fl. ounces. Centim'res. O.0S12 4.S99 39-194 Avoirdupois Wmghi 1 Ounce measures 1 Pound (16 ozs.) measures. . . Metric Weight. 1 Gramme measures Alcohol is used in pharmacy as a solvent and preservative for the medicinal properties of drugs. It is used in the prep- aration of medicines more frequently than any other sub- stance. It is much employed in the arts for various purposes. It is largely used in medicine as a stimulant, and in fact seems to be essential, in some form, to all people, in all countries, and in every avenue of life. 65. Alcohol Dilutum. Diluted Ale oho/, U. S., Spirit us Tenuior or Proof Spirit Br. Spirit us Dilutus, P. G. The present U. S. P. directs diluted Alcohol to be made by mixing equal weight of official Alcohol and water. It is de- scribed as " a liquid composed of 45.5 per cent, by weight (53 per cent, by volume) of Ethyl Alcohol, and 54.5 per cent, by weight (47 per cent, by volume) of water. Sp. gr. 0.928, at 15.6 C. (6o° F.)," It is made as follows: DILUTED ALCOHOL, U. S. 1880. By Weight. By Measure. Alcohol, sp. gr. .820, 50 parts or 16 ozs. av., 17 fl.ozs. Distilled Water, . 50 parts or 16 ozs. av., 14 fl.ozs. Mix. Sp. gr. 0.928, percentage of Ethyl Alcohol, by weight 45.5, by volume 53. ALCOHOLES — ALCOHOLS. 91 The 1870 U. S. diluted Alcohol was made as follows: DILUTED ALCOHOL, U. S. 1870. Alcohol, sp. gr. 0.835, j equal parts ) a pint. Distilled Water, ... (by measure, ! a pint. Mix. Sp. gr. 0.941, percentage of Ethyl Alcohol, by weight 39.3, by volume 46.6. It will be observed that the present U. S. diluted Alcohol is considerably stronger than the 1870. While it is desirable to have a preparation of sufficient alcoholic strength for the purpose, yet the 1880 diluted Alcohol seems unnecessarily strong for making most of the preparations in which it is employed, in fact, a much weaker menstruum could be as well used in most of them. Druggists, by the usage of a century, have made diluted Alcohol, by mixing equal measures of com- mercial Alcohol and water. While this may not be strictly scientific, it is the custom that has prevailed, and we find now, in spite of the directions of the 1880 Pharmacopoeia, that the practice is still continued, and that ninety-nine out of one hundred druggists now mix equal volumes of commercial Alcohol and water to make diluted Alcohol. This seems strong enough for all purposes for which diluted Alcohol is used, and we advise its adoption in all the formulas in this work in which diluted Alcohol is directed, except when specially marked U. S. 1880, or U. S. 1870, etc. DILUTED ALCOHOL, TO BE USED IN THESE FORMULAS. Commercial Alcohol, . \ equal parts ) a pint. Water, (by measure, * a pint. Mix. It contains about 43 per cent, by weight, or 50 per cent, by volume, of commercial Ethyl Alcohol. Sp. gr. at 72° F., 0.933. In working the formulae of the British or German authori- ties it is sometimes necessary to use the standard for diluted Alcohol adopted by them. We therefore give the formulas: PROOF SPIRIT (SPIRITUS TENUIOR), BR. 1885. Rectified Spirit, sp. gr. 0.838 5 pints. Distilled Water 3 pints. Mix. Sp. gr. 0.920. " It contains by weight about 49 92 ALO 'HOLES — ALCOHOLS. per cent., and by volume about 57 per cent, of absolute Alcohol." This, it will be seen, is considerably stronger than the U. S. diluted Alcohol. SPIRITUS DILUTUS (VERDUNNTER WEINGEIST), P. G. Alcohol, sp. gr. 0.830, by weight, 7 parts or ozs. av. Water, by weight, 3 parts or ozs. av. Mix. Sp. gr. 0.892. It contains by weight about 60 per cent., and by volume about 69 per cent, of absolute Alcohol, making it a fourth stronger than the U. S. official diluted Alcohol. Relation of Weight to Volume. — The change in the U. S. P. to parts by weight instead of fluid measure makes it necessary to thoroughly understand the relation between the weight and measure of diluted Alcohol. It is clearly shown in the follow- ing tables, which are calculated for U. S. 1880 official diluted Alcohol (equal parts by weight of Alcohol and water) : TABLE OF MEASURE, WITH WEIGHT EQUIVALENTS OF DILUTED ALCOHOL, SP. GR. 0.928 AT 15.6 C. (60 F.).* FLUID MEASURE. In Troy- Grains. In Troy Ounces. In Avoir. In Metric Ounces. Grammes American (Apothecary) Fluid Measure. 1 Minim weighs 1 Fluiddrachm weighs 1 Fluidounce weighs 1 Pint (16 fl ounces) weighs o.SS 52.8 422. S 6766.2 British (Imperial) Fluid Measure. 1 Minim weighs 1 Fluiddrachm weighs 1 Fluidounce weighs 1 Pint (20 fl. ounces) weighs. Metric Fluid Measure. 1 Cubic centimetre weighs 1 Litre weighs 406.1 3I22.0 15-3 [5347-2 0.001S O.IIO 0.881 14.146 0.0020 0.0571 0.121 3.42S 0.966 27.406 15.456 438.496 0.846 16.920 0.S4 0.001S 0.019 0.0548 50.8 0.108 0.116 3-2Sg 0.928 I 26.315 1S.562 526.308 0.032 0.035 °>9 2 5 31-973 35-io2 925.792 * Diluted Alcohol increases. or decreases in volume about ^^ for each Fahren- heit degree of temperature between 50° and 75°. ALCOHOLES — ALCOHOLS. 93 TABLE OF WEIGHT, WITH MEASURE EQUIVALENTS OF DILUTED ALCOHOL, SP. GR. 0.928 AT I5.6 : C. (6o D F.). In Ameri- can Minims, Apothecary Weight. 1 Grain measures 1.13 1 Drachm measures 68.1 1 Ounce (troy) measures 544-8 Avoirdupois Weight. 1 Ounce measures 495-4 1 Pound (16 oz.) measures 7626. S Metric Weight. 1 Gramme measures ... 16.6 American (Apotheca- ry) Fluid- ounces. O.OO23 O.142 1135 I.046 16.736 O.036 British (Imperial) Fluid Ounces. O.OO24 O.I48 1. 182 1-075 17.201 0.038 Metric Cubic Centime'rs. O.0702 4-213 33-702 30.583 4S9.32S When alcohol and water are mixed, a slight contraction of volume occurs with a rise in temperature. The greatest con- traction occurs when 52.6 volumes of alcohol are mixed with 47.4 volumes of water, it being 3.4 per cent. This should be taken into account when making specified quantities of diluted alcohol. Alcohol in Pharmacy. — Alcohol is used in pharmacy to extract or dissolve the properties of drugs and to preserve their solution. No other solvent of medicinal substances has been found of such universal value and application. A large- share of the liquid preparations that are used in pharmacy contain Alcohol and depend upon its solvent power and pre- servative virtue for their value. Besides this, it is used in making most of the solid extracts, abstracts, alkaloids, resin- oids, and many other solid preparations. The liquid preparations in which Alcohol is used as the sol- vent of medicinal principles, or for their preservation, may be classified as follows : Cordials and Elixirs, which contain aromatic substances, and mild medicines, sweetened and combined with sufficient Alco- hol to keep them and hold their properties in solution. Essences and Flavoring Extracts, which are mostly made From essential oils, or aromatic substances dissolved in Alcohol. 94 ALCOHOLES — ALCOHOLS. Fluid and Liquid Extracts, which contain a large quantity of medicinal value held in solution by Alcohol or diluted Alcohol. Liquors of all kinds, which are mainly Alcohol in some form, diluted and flavored with the substances peculiar to the kind. Spirits, which are solutions of essential oils, aromatic sub- stances, etc., in Alcohol, and among which may be included perfumes. Solutions, which contain Alcohol, either as a solvent or pre- servative, as solutions of gums, resins, acids, alkaloids, etc. Tinctures, which are mainly solutions of the medicinal prin- ciples of drugs in Alcohol or diluted Alcohol. To these may be added the abstracts, solid extracts, alka- loids, and medicinal principles of drugs generally, which are obtained by the aid of Alcohol, and it will be seen that in pharmacy it is the most important of any substance, in fact, entirely indispensable in its practice. In French pharmacy Alcohol is called A/coo/, and alcoholic preparations are classified according to the manner of prepar- ing them and the substances used in them. Alcoolats or Alcoholates are medicated distilled spirits, made by macerating aromatic and other substances with Alco- hol, and distilling. We have no official preparations that cor- respond with them. They will be noticed under the headings Distillates, Essences, Spirits, Tinctures, etc. Alcoolateures. — These are tinctures prepared by macerat- ing fresh plants (roots, barks, seeds, leaves, flowers, etc.) in Alcohol. They correspond very nearly to what are known in this country as green plant fluid extracts. They are made by macerating equal parts by weight of the fresh substance, prop- erly cut, bruised or divided, in ninety per cent. Alcohol, for ten days, then pouring off the liquid, pressing the drugs, and filtering the extract thus obtained. As our green plant fluid extracts are so similar, these preparations will not be further noticed. Alcooles. — These are simple solutions of medicinal sub- stances in Alcohol. Among them are the mixtures of acids, ALCOHOLES — ALCOHOLS. 95 ammonia, etc., with Alcohol and the solutions of alkaloids and their salts, phosphorus, carbonate of potassium, soap, etc., which are not properly classified under the head of " Tinctures Alcoholiques." We have included these under the general heading- "Tinctures." Besides the above-mentioned prepara- tions containing Alcohol, are those which are classified the same as in our own works, which will be noticed under their proper headings, as Elixirs, Essences, Extracts, Spirits, Tinc- tures', etc. 66. Alcohol Amylicum, Br. Amylic Alcohol — Fousel Oil — Hydrate of Amy I. C 5 H tl HO. This is a " liquid of oily consistence contained in the crude spirit produced by the fermentation of saccharine solutions with yeast, and separated in the rectification or distillation of such crude spirit." It is a hydrate of the radical amyl (C 5 H X 1 ), and is commercially known as Fusel or Fousel Oil. When pure its sp. gr. is 0.818. It boils at 1 32 0.(269.6° F.). It is the base of many of the so-called fruit ethers or artificial fruit flavors and of most of the artificial liquor flavors, and is used in medicine for making nitrate of Amyl and valerianate of sodium. 67. Alcohol Methylicum. Met hylic Alcohol— Wood Alcohol— Wood Naphtha — Hydrate of Mi 'thj 7 — Carbinol. CH3HO. This Alcohol is produced by the destructive distillation of wood, hence it is called Wood Alcohol, pyroxylic spirit or wood naphtha. It is chemically a hydrate of the radical methyl (CH 8 ); its specific gravity is 0.798; it boils at about 65° C. (149 !•".). It is used considerably in making varnishes and many other preparations as a substitute for Alcohol, but on account <>f its peculiar odor cannot replace Ethyl Alcohol in medicinal preparations, but is considerably used in making some kinds of chemicals, as salicylic acid, etc. It was formerly used for consumption and chronic catarrh; but its internal administration is nearly abandoned. 96 ALDEHYDES - ALDEIIVDS. ALDEHYDES — ALDEHYDS. Aldehyds are derived from Alcohols by the elimination of H 2 from the hydrates of the Alcohol radicals. Aldehyds corresponding to eleven of the primary Alcohols have been discovered. Although but one is known in pharmacy, namely, Acetic Aldehyd, C 2 H 4 (from Ethyl Alcohol), and that is sel- dom used. The chemical composition of several of the aldehyds will be found on page 85. The aldehyds are intermediate in position between alcohols and acids — the first step in the oxidation (or dehydration) of alcohols, which, when continued, converts them into acids. They unite with ammonia, forming aldehyd-ammonias, which by losing H 2 condense into the basic substances aldines and oxaldines. The aromatic aldehyds, as benzoic, cumic, salicylic, cinnamic, etc., are obtained from essential oils or plants, and when acted upon by ammonia produce hydramides. 68. Aldehyd. Acetic Aldehyd. C 2 H 4 0. Aldehyd is made by mixing three parts of eighty per cent. Alcohol with two parts of nitric acid, distilling, purifying, sep- arating and redistilling. The nitric acid combines with the Alcohol and unites with a portion of its hydrogen to form nitrous ether and aldehyd, which are distilled and treated with ammonia gas. The nitrous ether separates as a layer floating on the solution of ammonia aldehyd, the latter is then mixed with diluted sulphuric acid, and redistilled over chloride of calcium. The sp. gr. of aldehyd is 0.805 at °° C. (32° F.). It is antiputrescent, and has properties somewhat similar to ether, but is not used in medicine. Several of its derivatives, how- ever, as chloroform and chloral, are much employed. Acetals are compounds made by combining aldehyds and alcohols with elimination of water. Bromal, Iodal, Chloral, and Butyl Chloral are derivatives of aldehyd. ALDEHYDES — ALDEHYDS. ALKALIES. 97 69. Paraldehyd. This has recently come into use as a hypnotic and anodyne. It contains the same elements in the same proportions as aldehyd, but in triple combination: C 6 H 12 3 = 3C 2 H 4 0. It is made by acting upon aldehyd with small quantities of mineral acids or zinc chloride, or by adding a few drops of concentrated sulphuric acid to aldehyd, and subsequent distillation. It is a colorless liquid at ordinary temperature, solid at 50 F., soluble in cold water or elixir. The adult dose is from half to one and one half fluiddrachm. It has not yet come into general use, but is thus far very favorably received. ALKALIES. Commercially, the hydrate of sodium (caustic soda) and the hydrate of potassium (caustic potassa) only, are known as Alkalies, but in pharmacy the carbonates of these metals and of ammonia, the solution of gaseous ammonia in water (water of ammonia) and, indirectly, the hydrates and carbonates of lithium, barium, calcium, strontium, and magnesium are classed with the Alkalies. In a general way, Alkalies are known as bases, which combine with fatty acids to form soaps or oleates ; which combine with acids to form neutral salts ; which turn red litmus blue or yellow turmeric brown, and which are in every way the reverse of acids. The manufacture of soda and potassa Alkalies constitutes a great commercial industry. These manufactures are known as alkali-works, and are mostly devoted to the manufacture of Soda Alkali. The Soda Ash of commerce is the impure carbonate of sodium, which is the basis of the Soda Alkali. Potash or Pcarlash is impure carbonate of potash, the base of the Potassa Alkali. The Alkalies form the bases of a great variety of chemicals which are used in medicine, and are exten- sively employed in many important manufacturing industries and in the arts. They are sometimes named from their source 98 ALKALOIDES — ALKALOIDS. of supply, as ammonia is called animal alkali ; potassa, veget- able alkali ; soda, mineral alkali ; barium, calcium, strontium, and magnesia, alkaline earths, etc. The Alkalies and their uses will be further noticed under the headings of the sub- stances which compose them. ALKALOIDES — ALKALOIDS. The name Alkaloids is given to a class of organic bases which (like alkalies) combine with acids to form salts. The Alkaloids and their salts represent the active medicinal prop- erties of most vegetable drugs and form a very important class of chemicals. The manufacture of Alkaloids and their salts is chiefly carried on by manufacturing chemists, and a large amount of capital is thus employed. Alkaloids may be classed as natural and artificial. The natural Alkaloids are obtained from organic substances (animal or vegetable) in which they exist combined with other sub- stances, and the artificial are produced by the skill of the chemist. The natural Alkaloids all contain nitrogen, with hydrogen as a base, and are probably derivatives of the ammo- nia type (NH 3 ). Carbon is present in all, and oxygen in most of them. Alkaloids which contain the four elements C, H, N, O, are called AMIDES. They are generally non-volatile crystalliz- able solids, representing the active principles of vegetable and animal substances from which they are obtained. Alkaloids which contain only the three elements C, H, N, are called AMINES. They are generally volatile liquids, artificially made by substituting hydrocarbon radicals wholly or partly for the hydrogen of the typical ammonia base. Considerable confusion formerly existed because of the lack of uniformity of the termination of the names of Alkaloids — some ending with ia and some with ine, as morphia, quinine, etc., but in the late revisions of the American and British Pharmacopoeias the terminal letters of the names of the Alka- loids are uniformly ine. It should, therefore, be remembered that in older works of pharmacy the names of Alkaloids that terminated in ia would now be written ine. ALKALOIDES — ALKALOIDS. 99 As Alkaloids are, so to speak, the concentrated principles of the substances from which they are derived they are very powerful, compared with the crude substances, the dose of many of them being very minute. Their salts, being more soluble, are mainly used in medicine. Several Alkaloids varying in composition and characteristics are sometimes obtained from one plant, but in the main they are true repre- sentatives of the drug in properties and actions. Alkaloids are generally insoluble or but sparingly soluble in water, but are readily dissolved in alcohol, chloroform, and the liquid hydrocarbons. They form salts with acids, generally soluble in water. From aqueous solutions of these salts the Alkaloids are precipitated by alkalies, because of the stronger attraction of their acids for the alkali than the alkaloidal base. The Alkaloids are mainly used in pharmacy as bases for preparing their salts, and are but little employed in medicine, their soluble salts being used instead. It is therefore unneces- sary to give explicit formulae for all of them, but only such as are more frequently employed and general processes which may apply to the remainder. The following general directions for preparing Alkaloids from crude drugs are therefore given, but it may be stated that they can only be considered general directions, and that some special treatment, requiring experience and chemical know ledge is necessary to successfully obtain and separate the Alkaloids of most substances. They are, therefore, generally supplied by competent manufacturing chemists. 70. General Directions for Preparing Alkaloids. I. FOR ALKALOIDS SLIGHTLY SOLUBLE IN WATER, OR WHICH EXIST IN THE PLANTS, ETC., IN THE FORM OF ACIDS, OR SOLUBLE SALTS OF ALKALOIDS. Macerate the drug, in coarse powder, twenty-four hours, in water sufficient to cover it, then pack it moderately in the water-bath percolator, adding water freely, and heat to boiling; then begin to percolate, adding water through the percolator, and continuing the heat and percolation until the drug is 100 AI.KALOIDES — ALKALOIDS. exhausted ; strain the percolate while hot and slowly add to the liquid water of ammonia or liquor of potassa as long as it continues to precipitate, allow to settle, pour off the liquid, pour the precipitate upon a filter, wash with a little water, press, dissolve in very dilute acetic or hydrochloric acid, pre- cipitate again with ammonia or potassa, pour off, drain, and repeat the operation as many times as may be necessary to purify the Alkaloids. The product is the Alkaloids of the drug, which are partially soluble in water. If necessary, they must be separated by various means, recrystallized and dried. The liquors which are poured off contain a small percentage of the Alkaloids, which may be recovered by evaporating them and treating in the same manner as directed. II. FOR ALKALOIDS INSOLUBLE IN WATER. Macerate the drug, in moderately fine powder, for twenty- four hours, with sufficient alcohol to cover it, pack firmly in the water-bath percolator, pour alcohol upon it, heat moder- ately for an hour and begin to percolate, adding alcohol to the drug and continuing the heat and percolation until its strength is exhausted ; distil off most of the alcohol and to the residue add sufficient very dilute acetic or muriatic acid to dissolve the Alkaloids that are in the soft extract ; this is best accom- plished by washing it with several portions of the dilute acid ; filter the acid solution and add to it sufficient water of ammo- nia or liquor potassa to precipitate the Alkaloids, wash the precipitate on a filter with water, and redissolve and reprecipi- tate if necessary. The product is the Alkaloids soluble in alcohol that were contained in the drug, and they must be separated if necessary. Many other processes are employed for obtaining Alkaloids, as boiling the drug with dilute acid, precipitating with an alkali, etc., but the foregoing are sufficient to show the general methods. It may be explained in regard to the foregoing processes that the heat employed serves to dissolve the alka- loids, the same as the acids which are used in other processes, and the subsequent treatment is less troublesome ; for exam- ple : Strychnine dissolves in 12 parts of boiling or 1 10 parts of cold alcohol ; quinine in 2 parts boiling or 6 parts of cold ALKALOIDES — ALKALOIDS. 101 alcohol ; caffeine in 10 parts of boiling or 75 parts of cold water; therefore, when drugs are percolated with a boiling or heated menstruum, their alkaloids are as readily dissolved as when acids are used, and their subsequent separation is much more simple. The following are the more important Alkaloids which have been sufficiently investigated to receive reliable recognition and formulas. Many others, of course, exist, for it may be assumed that every genus of plants has its characteristic basic principle or principles which may be isolated, but only the more important ones have thus far received attention. Important Alkaloids and their Salts. Of the Alkaloids known and named by chemists, but few are used in medicine, and most of them are unimportant except as chemical products and curiosities. Of the small number which are used in medicine but few are employed as Alkaloids, but mainly as salts formed by the union of these organic bases with acids. The Alkaloids are generally used for making the oleates, because they will combine with oleic acid, while their salts will not. Some of them are also employed in delicate prepar- ations, where the acids with which they are combined as salts would be inadmissible. The following important Alkaloids and their salts are those which are frequently used in medicine : 71. Aconitina. Aconitine — {Formerly called Aconitid). C„H i:i N0 12 . Tin's Alkaloid was formerly official, but has now been drop- ped from the L'. S. 1\ It is still retained in the Br. P., and is much more used than formerly. It is present in Aconite, associated with several other Alkaloids, as pseud-aconitine, C,,l I„\'o n ; pier aconitine \ C :; ,l [ M No M ; aconine, ( '.,,•. I l,,,N( ),, ; pseud- aconine, ( ,, ; H 4 ,NO g ; aconitic acid, H 3 C H s O 8 , etc. 102 ALKALOIDES — ALKALOIDS. Owing to the many varieties of Aconite Root of commerce which yield different Alkaloids, any general formula which would apply to all would be uncertain in its results, as different varieties of Aconite yield different Alkaloids. This Alkaloid is, therefore, chiefly manufactured by a few manufacturing chemists who have made a reputation for their particular make. The crystallized Aconitine, made by the French chem- ist Duquesnal, stands the highest ; but the most that is found in the market is amorphous, and is supplied by other chemical establishments of good repute. The following general pro- cess, which very much resembles that of the Br. P., except in the manner of extracting the drug, may be employed : . ■ ., -r, , . , | any convenient Aconite Root, in coarse powder, > J ) quantity. Alcohol, I Diluted Sulphuric Acid, ... „ . „, -r, , - a sufficient Stronger Lvther ttt , r a ■ I quantity. Water of Ammonia, > J Moisten the Aconite Root with one-half its weight of Alco- hol, and pack it firmly in the water-bath percolator; pour upon it sufficient alcohol to cover it, and set it in a warm place for four days, then heat very moderately, and after one hour begin to percolate, adding alcohol to the drug and continuing the heat and percolation until it is exhausted. Distil off nearly all the alcohol by means of the water-bath and still, and add to the soft extract which remains, for each pound of the drug which was taken, half a pint of water, acidulated with half an ounce of diluted sulphuric acid. Heat this gently by water- bath until all the spirit has been evaporated, and filter through paper to remove resinous and oily substances. To this liquid add water of ammonia to slight excess and heat gently by water-bath until no odor of ammonia remains ; separate the precipitate by filtration and carefully dry it, reduce it to a coarse powder and shake it with successive portions of ether, which dissolves the Aconitine ; mix the several etherial wash- ings and distil off the ether, or allow it to evaporate sponta- neously, then dissolve the residual extract thus obtained in water acidulated with sufficient diluted sulphuric acid ; repre- ALKALOIDES — ALKALOIDS. 103 cipitate by carefully adding water of ammonia, collect the precipitate upon a filter and wash with a little water, then dry. The product is Amorphous Aconitine. The following process for making crystallized Aconitine was proposed by John Williams, F. C. S., at the August, 1886, meeting of the Br. Pharmaceutical Council. The root of Aconitum Napclhis only should be used : The root should be brought to the state of a coarse powder only ; if made very fine it is difficult to work. It should be exhausted with spirit of full strength (rectified spirit), say 62 to 64 per cent., about four ounces of tartaric acid to each cwt. of the root should be dissolved in the spirit ; cold maceration for about four days, followed by percolation, returning the per- colate to the root for the second maceration of a day, then percolating until the drug is exhausted and a very concen- trated tincture is obtained. The spirit must now be dis- tilled off at the lowest possible temperature, but the dis- tillation should be stopped and a little hot water added before all the spirit has passed over. The evaporation by water-bath is then to be continued by gentle heat until all traces of spirit have been driven off. The thin aqueous extract is then to be filtered through coarse wetted filter paper, which separates the resinous and a portion of the oily matter; the remainder of the oily matter is then removed by shaking with ether, the ether is separated and to the remaining puri- fied aqueous extract a slight excess of concentrated solution of carbonate of sodium (sal soda) is added, which precipitates the Alkaloid ; this is heated and the Alkaloid separates into a mass, which is to be washed on a filter with hot water, then dried and macerated in several portions of pure ether. The ether washings are then to be mixed, filtered and allowed to evaporate spontaneously. Crystals of Aconitine may then be collected, drained and dried. Aconitine has been used externally in the form of an oint- ment and oleate; the former is official in the Br. P. (see Oint- ments), and the latter is supplied by manufacturing pharma- cists. (Sec Oleates.) On account of its great power and the uncertainty <>f the preparations <>n the market, it has been but 104 ALKALOIDES — ALKALOIDS. little used internally; but as more reliable and uniform Acon- itine is now being produced, it is beginning to be more employed. It is generally used as a trituration : one part Aconitine with 500 parts sugar of milk. The dose of Aconitine is from -g-^ to ^-jU^ of a grain, hence the dose of a trituration 1:500 would be from 1 to 2 grains. It is used for the same purposes as Aconite in fevers, neuralgia, etc. The following salts of Aconitine are sometimes used : Nitrate of Aconitine. — This is prepared by exhausting Aconite root with alcohol, as directed for making Aconitine, distilling off the alcohol, adding boiling water and a slight excess of water of ammonia, filtering, dissolving the filtrate in water acidulated with nitric acid, evaporating and crystalliz- ing. The crystals are then dissolved and purified by recrys- tallization. Sulphate of Aconitine. — This is prepared in the same man- ner as the nitrate, except that sulphuric acid is used instead of nitric. These Alkaloids are readily soluble and possess the same properties as Aconitine. The dose, when administered internally, is from 3--^ to -^0 grain. 72. Apomorphina. Apomorphinc — {Apomorphia.) C 17 H 17 N0 3 . The Alkaloid is seldom used, and when wanted may be most conveniently prepared from its hydrochlorate, which is the official salt employed in medicine. It may be made by dissolving the hydrochlorate of Apomorphine in water, precip- itating it with bicarbonate of sodium, washing the precipitate with a little cold water and drying quickly by gentle heat. Apomorphine is morphine deprived of one molecule of water, as shown in the following formula : C 17 H 19 N0 3 — H 2 = C 17 H 17 N0 2 . Morphine. Wat er. Apomorphine. ALKALOIDES — ALKALOIDS. 105 73. Apomorphinae Hydrochloras. Hydrochlorate of Apomorphine. C 17 H 17 N0 2 HC1. This salt, which was made official in the last U. S. P., may be prepared by heating one part of morphine with twenty parts of pure hydrochloric acid in a strong glass or metal tube of at least fifteen times the capacity of the substances introduced. The tube must be securely sealed and the heat is best regu- lated by means of an oil-bath, by which it can be maintained for three hours at a temperature of 140 to 150 C. (284° to 302 F.). After heating in this manner the tube is cooled and its contents dissolved in water; bicarbonate of sodium in excess is then added, and, when the precipitate has subsided, the liquid is poured off and the precipitate shaken with succes- sive portions of ether, which dissolves the apomorphine ; a few drops of hydrochloric acid are then added to the etherial washings and, after standing, crystals of hydrochlorate of mor- phine are found (the acid uniting with the apomorphine and separating from the ether because the salt is insoluble in ether). The crystals are then dissolved in boiling water, and recrystal- lized, making the pure hydrochlorate of apomorphine, which is employed in medicine. Uses. — This salt is powerfully emetic and sedative, but does not possess narcotic principles. It has recently gained favor with physicians and is being considerably prescribed. The usual adult dose is from yi to J^ grain, or, when injected hypo- dermically fa to -fa grain. 74. Atropina. A tr opine — {A tropin.) • C„H„NO,. This is the principle Alkaloid of belladonna, official in the U. S., Br. and German pharmacopoeias. It may be prepared 106 ALKALOIDES — ALKALOIDS. by the following process, which is in part adopted from the 1885 Br. P.: Belladonna Root, in coarse powder, . . 2 pounds. Alcohol, a sufficient quantity. Slacked Lime, 1 ounce. Diluted Sulphuric Acid, ) , „ . ~ , , ;D , . - of each a sufficient quantity. Carbonate or Potassium, ( n J Chloroform 3 fl. ounces. Purified Animal Charcoal, sufficient. Distilled Water, jo fl. ounces. Moisten the powder with a pint of alcohol, pack firmly in the water-bath percolator, and pour alcohol upon it until the drug is covered ; set in a warm place to macerate for two days, then heat very moderately and, after one hour, begin to perco- late, adding alcohol, and continuing the heat and percolation until the drug is exhausted; add the lime to the tincture thus obtained and agitate thoroughly, then filter ; add sufficient diluted sulphuric acid to the filtrate to acidulate it slightly; filter again, distil off most of the alcohol, add the distilled water and evaporate until no odor of alcohol remains ; then cool and carefully add carbonate of potassium dissolved in water to nearly neutralize the acid, taking care not to add an excess, and set aside for several hours ; then filter, and add an excess of carbonate of potassium, then the chloroform, and agitate thoroughly for some time, allow to separate, pour off the upper liquid, distil the chloroform from the remainder, dissolve the residue in a little warm alcohol, digest the solution with a little animal charcoal, filter, evaporate and cool, until colorless crystals of atropine are obtained. Uses. — On account of its insolubility Atropine is but little used except in oleates and ointments. It has the same prop- erties as belladonna, and is a narcotic. Dose, y4-o to -^ grain in trituration. 75. Atropinae Sulphas. Sulphate of Atropine — (Sulphate of Atropia.) Atropine, 120 grains. Distilled Water, 4 fl. drachms. . Diluted Sulphuric Acid, sufficient. ALKALOIDES — ALKALOIDS. 107 Rub the Atropine first to a fine powder and then to a smooth mixture with the water, and add diluted sulphuric acid, drop by drop, until the Alkaloid is dissolved and the solution is neutral. Evaporate the solution to dryness at a temperature not exceeding Z7-7°° C. (ioo° F.). Uses. — This salt is quite soluble in water, and its solution (i to ioo) is employed as a mydriatic (to dilate the pupil of the eye i and for other purposes in which the action of bella- donna is desired. The adult dose, internally, is T |- ¥ to -^ grain or less in trituration. 76. Beberina. Beberine — {Beberia — Bibiria.) C 36 H 43 N 3 6 . This Alkaloid is obtained from nectandra or bebeeru bark, in which it exists combined with nectandrine (C 40 H 46 N 3 O 8 ) and other Alkaloids. It is identical with buxine, from box, and pelosine or cissampeline, from pareira. The Alkaloid is not used in medicine but its sulphate is offi- cial in the Br. P., and the Alkaloid may be prepared from it if desired by decomposing its solution in hot water with water of ammonia, and washing and drying the precipitate. From the similarity of names care must be taken not to dispense bebe- rine or its salts when forberine is ordered, and vice versa. 77. Beberinae Sulphas, Br. Sulphate of Beberine — {Sulphate of Beberia.) The following is the formula official in the Br. P. : Bebeeru Bark, in coarse powder, . 1 pound av. Sulphuric Acid, x / 2 fl. ounce. Slacked Lime, q. s., or ^ ounce av. Solution of Ammonia, a sufficiency. Rectified Spirit, 16 fl. ounces. Diluted Sulphuric Acid, a sufficiency. Water, 154 fl. ounces. I distilled Water, a sufficiency. 108 ALKALOIDES — ALKALOIDS. Add the sulphuric acid to the water, pour upon the bebeeru bark enough of the mixture to moisten it thoroughly; let it macerate for twenty-four hours, place it in a percolator and pass through it the remainder of the acidulated water ; con- centrate the acid percolate to 20 fl. ounces, cool and add grad- ually the lime in the form of milk of lime, agitating well, and taking care that the fluid still retains a distinct acid reaction ; let it rest for two hours, filter through calico, wash the precip- itate with a little cold distilled water, and to the filtrate add solution of ammonia until the fluid has a faint ammoniacal odor ; collect the precipitate on a cloth, wash it twice with 10 ounces of cold water, squeeze it gently with the hand and dry it by the heat of a water-bath ; pulverize the precipitate and wash with separate portions of the spirit, mix the washings, add 4 ounces of distilled water and distil the greater part of the spirit ; to the residue add with agitation diluted sulphuric acid until the fluid has a slight acid reaction; evaporate to dryness, dissolve in distilled water, filter, evaporate to a syrupy consist- ence, spread on glass plates, and dry by a temperature not exceeding 140 F. (6o° C). This is used as a substitute for quinine, or, rather, its action is similar to it, but it cannot be considered its equal. The dose is from 1 to 10 grains. 78. Berberina. Berbcrinc — (Berberia.) C 20 H 17 NO 4 . The Alkaloid Berberine is found in a large number of plants, but is most abundant in hydrastis, columbo, gold-thread and several species of barberry. It may be obtained by several methods ; but, perhaps, the simplest and the best is by boiling the coarsely-powdered barks or roots, or, preferably, percolating them in the water-bath percolator with boiling water until they are exhausted. The decoction is then to be evaporated to a soft extract and washed with successive portions of alcohol to dissolve out the Berberine ; to the alcoholic washings, mixed and filtered, a little water is then to be added and the alco- hol distilled off by means of a water-bath ; the remaining ALKALOIDES — ALKALOIDS. 109 liquid is then condensed, allowed to cool, and crystals of Ber- berine will form ; these may be purified by dissolving in hot water and recrystallizing. Uses. — The Alkaloid is but little used, but its salts are extensively employed in medicine. It is a tonic to the mucous membrane, a bitter stomachic and general alterative, and has properties similar to quinine. The dose is from i to 8 grains. 79. Berberinae Hydrochloras. Hydrochlorate of Berberine. This salt, which was formerly known as hydrastin, is gener- ally prepared from golden seal. A decoction may be made, evaporated and treated with alcohol in the same manner as is directed for making Berberine. A little water, acidulated with hydrochloric acid, is then to be added to the alcoholic solution, the alcohol distilled, and the remaining liquid set aside, in which crystals of Hydrochlorate of Berberine will form ; these are to be drained from the mother liquor, dis- solved in hot water and purified by recrystallization. It can also be prepared from the Alkaloid berberine by dis- solving it in hot water, acidulated with hydrochloric acid, allowing to crystallize, and purifying by recrystallizing from hot water. This sajt gained considerable notoriety as an eclectic remedy under the name of hydrastin, and was afterwards known as muriate of hydrastin ; but this salt, which is of a bright yellow color, has been shown to be the Hydrochlorate of Berberine, the salts of hydrastine being white instead. Uses. — Its uses are similar to the Alkaloid — a tonic to the mucous surfaces, etc. It is much used in atonic dyspepsia and weakness of the digestive tract. Dose, 1 to 4 grains. 80., Berberinae Sulphas. Sulphate of Berberine. This is prepared by dissolving Berberine in hot water, acid- ulated with sulphuric acid, crystallizing, redissolving the crys- tals in hot water and recrystallizing; or may be made directly 110 ALKALOIDES — ALKALOIDS. from the barks or roots containing Berberine in the same manner as is directed for making Berberine, except that water, acidulated with sulphuric acid, instead of water, must be added to the alcoholic solution before distillation. Uses. — The uses of this salt are similar to the Alkaloid. It is also used in making elixirs, etc. The dose is from i to 4 grains. 81. Caffeina. Caffeine — TJieine — Guaranine. C 8 H 10 N 4 O 2 ,H 2 O. Coffee, tea, some other plants, and guarana contain an iden- tical Alkaloid called Caffeine. Coffee contains about 1 per cent., tea 1^ to 4 per cent., and guarana 4 to 5 per cent, of this Alkaloid. It is prepared from these substances by boiling them in water to make a strong decoction, precipitating the decoction with acetate of lead to remove astringent and other matter, filtering, passing sulphuretted hydrogen gas through the filtrate to remove excess of lead, filtering again, adding water of ammonia, evaporating and recrystallizing. It is sel- dom made except by manufacturing chemists. Uses. — Caffeine is used as a nerve stimulant in sick and nervous headache and periodic nervous derangements. The dose is from 1 to 5 grains. 82. Caffeinae Citras, Br. Citrate of Caffeine. C 8 H 10 N 4 O 2 ,H 3 C 6 H 5 O 7 . Caffeine, 1 ounce. Citric Acid, 1 ounce. Distilled Water, 2 ounces. Dissolve the citric acid in the water and stir the Caffeine into the heated solution ; evaporate to dryness on a water-bath, constantly stirring towards the end of the operation. The properties and uses of this preparation are the same as Caffeine. The dose is from 2 to 10 grains. It may be con- veniently given in the form of an elixir. ALKALOIDES — ■ ALKALOIDS. Ill 83. Chinoidium. Chinoidin — Chinoidine. ( Quinoidin.) In the manufacture of Quinine, after all the crystallizable salts have been obtained from the mother liquors, there remains a black amorphous mass, consisting of the mixed uncrystallizable Alkaloids of chinchona bark, mainly quinici)ie and cinchonicine, which are isomeric with Quinine and Cincho- nine, and have been produced by the action of heat upon them. To this mass is given the name Chinoidin or Quinoidin. It has properties similar to other Alkaloids from cinchona bark and is considerably used as an anti-periodic, forming the base of most of the " ague pills " that are made. Dose from 3 to 30 grains. 84. Cinchonidinae Sulphas. Sulphate of Cinchonidine — {Sulphate of Cinchonidial) (C 20 H 24 N 2 O) 2 H 2 SO 4 . 3 H 2 O. This salt remains dissolved in the mother liquors after the crystallization of sulphate of quinine, and is obtained from them by concentrating the liquors and crystallizing. As Sulphate of Cinchonidine is less soluble than sulphate of cinchonine, its crystals may be separated before the liquors are treated to obtain cinchonine. The barks from India contain a greater proportion of the Alkaloid Cinchonodine than those from South America. It resembles sulphate of quinine more than any other salt of cinchona, both in its appearance and action, and is much used as a substitute for it, the dose being about a third greater. It is tonic, febrifuge and anti-periodic. Cinchonidine. --The Alkaloid from which the Sulphate of Cinchonidine is derived is not used in medicine or pharmacy. Its chemical composition is the same as cinchonine, but the arrangement of its molecules admits of its combining with one more molecule of water, when it forms salts with acids. J V2 ALKALOIDES — ALKALOIDS. 85. Cinchonina. Cinchonine — ( Cinchonia.) C 30 H 24 N 2 O. In the manufacture of sulphate of quinine, after it has crys- tallized from its solution, sulphate of Cinchonine, which is more soluble, remains dissolved in the mother waters. By adding ammonia or solution of soda to the mother waters Cinchonine is precipitated and may be collected on a filter, washed with water, dried and dissolved in boiling alcohol, from which it is crystallized on cooling. It is but little used in medicine or pharmacy, on account of the greater value and solubility of other salts of Cinchona. 86. Cinchoninae Sulphas. Sulphate of Cinchonine — {Sulphate of Cinchonia 1) (C 20 H 24 N 2 O) 2 H 2 SO 4 2H 2 O. This salt is readily made by dissolving Cinchonine in dilute sulphuric acid and crystallizing. It is contained also in the mother liquor after the crystallization of sulphate of quinine, and may be obtained as Cinchonine and converted into the sulphate as above. Uses. — Sulphate of Cinchonine has properties similar to sul- phate of quinine, but may be given in much larger doses. It is more frequently used as a tonic than as an anti-periodic. The usual dose is from 2 to 5 grains ; but from 20 to 40 grains are often given as an anti-periodic. 87. Cocaina. Cocaine ■ — ErytJiroxyline. C 17 H 21 N0 4 . ■ This Alkaloid and its salts, which have created such a furore in the medical world, are made from the leaves of erythroxy- lon coca. It may be prepared from its hydrochlorate, which is chiefly used, by precipitating an aqueous solution of hydro- ALKALOIDES — ALKALOIDS. 113 chlorate of cocaine with carbonate of sodium and washing and drying the precipitate. 88. Cocainae Hydrochloras, Br. Hydrochlorate of Cocaine. C 17 H 21 N0 4 HC1. Many processes for making Hydrochlorate of Cocaine have been proposed since it has been introduced; but they are all similar to the process employed for making other Alkaloids of the same class. The following is selected as the best for the general convenience of druggists : Coca Leaves, in coarse powder, ... 2 pounds. Alcohol, a sufficient quantity. Diluted Hydrochloric Acid, a sufficient quantity. Carbonate of Sodium, a sufficient quantity. Ether, 4 fl. ounces. Distilled Water, 2 pints. Animal Charcoal, I ounce. Moisten the powder with a pint of alcohol, pack firmly in the water-bath percolator, cover the drug with alcohol and let stand in a warm place for two days ; then heat moderately and begin to percolate, adding alcohol to the drug and continuing the heat and percolation until the drug is exhausted ; distil off most of the alcohol, add the water and evaporate until all traces of alcohol have disappeared ; add sufficient diluted hydrochloric acid to slightly acidulate the liquid, filter; add sufficient solution of carbonate of sodium to precipitate the Alkaloid; dissolve the Alkaloid' from the solution by shaking with ether; separate and evaporate the etherial solution; dis- solve the residue in alcohol, mix with the purified animal char- coal, filter; add diluted hydrochloric acid and water to the filtrate ; distil off the alcohol ; evaporate and collect the crystals of Hydrochlorate of Cocaine from the liquid and dry them on bibulous paper. Uses.- Hydrochlorate of Cocaine is used in solution as a local anaesthetic in ophthalmic and other delicate surgical prac- The solutions employed are generally from two to four 114 ALKALOIDES — ALKALOIDS. per cent, of the salt in distilled water. They are applied by brushing over the parts. It is also somewhat employed inter- nally as an anodyne and intoxicant, in doses of ^ to I grain. 89. Codeina, U. S., Br. Codeine — (Code ia. ) C 18 H 31 N0 3 .H 2 0. This Alkaloid, obtained from opium, stands next in import- ance to morphine, and is now being extensively used by phy- sicians. It is obtained from the ammoniacal liquor left after the crystallization of morphine (see Morphine), by evaporating and crystallizing. As thus obtained it contains impurities which may be removed by dissolving in hot ether and allowing to evaporate spontaneously and crystallize. Codeine is one of the most soluble Alkaloids known and is generally used in preference to any of its salts. It has lately come into notice and favor, and in England, especially, is being much used. Codeinae Sulphas. — Sulphate of Codeine is made by dis- solving Codeine in a very small quantity of dilute sulphuric acid, evaporating and crystallizing. It possesses no advan- tages over the Alkaloid except that it is more soluble, and is seldom used. Its uses and dose are the same as Codeine. Uses.- — Codeine is a sedative, but possesses only slight nar- cotic properties. The dose is ^ to I grain. 90. Colchicina. Colchicine. C 17 H 33 N0 6 . This Alkaloid is the active principle of Colchicum Antum- nale, and is obtained from the seeds, flowers, or corm of the plant, in the same manner as is employed for aconitine. Its uses are the same as Colchicum, and the dose is from y^- to -^ ALKALOIDES — ALKALOIDS. 115 91. Conina. Conine — (Coma.) C 8 H 17 N. The valuable medicinal principle of Conium is a volatile liquid Alkaloid called Conine or Coniine. It is obtained by exhausting Conium with boiling water in the water-bath per- colator, and distilling the percolate until about one third passes over. This portion contains the volatile Alkaloid, which is separated from its solution by first filtering through animal charcoal to remove traces of oil and resin, then shaking the filtrate with ether, pouring off the etherial solution which contains the Alkaloid, and allowing the ether to evaporate spontaneously ; the liquid remaining after the evaporation of ether is Conine. It contains no oxygen, is soluble in water, alcohol or ether, and has a peculiar odor resembling the urine of mice. Conium also contains conhydrine C 8 H 17 NO, and Methylcon- ine C 8 H 16 CH 3 N, which remain after the separation of Conine, and have properties similar to it. Conine unites with acids to form salts ; the hydrochlorate of Conine is the salt usually prescribed. It is narcotic and seda- grain. 92. Daturina. Daturinc — {Daturia.) This is obtained from the seeds or leaves of Datura Stram- onium, but has proven to be a mixture of hyoscyamine and atropine instead of a distinctive Alkaloid. It is a narcotic poison, having the same properties and uses as Stramonium. It is generally prescribed in the form of Sul- phate of Daturine, the dose being r ^ to -^ grain. 93. Duboisina. Duboisine- I Duboisia.) This Alkaloid is obtained from the leaves of several species oi Duboisia found in Australia. It is a very poisonous Alka- 116 ALKALOIDES — ALKALOIDS. loid, similar in characteristics and action to atropine, for which it is used as a substitute. It may be prepared in the same manner as atropine (which see). Sulphate of Duboisine is the soluble salt generally em- ployed. It is given internally in doses of jfo to -gL- grain, and its solution is employed as a mydriatic in the same manner as sulphate of atropine. 94. Emetina. Emetine — { Evict ia or Evict inia.) C 28 H 40 N 2 O 5 . The active principle of ipecac is the Alkaloid Emetine. It also exists in some other plants. It is prepared from ipecac, which yields about I per cent, of the Alkaloid, by exhausting the drug with alcohol, by means of the water-bath percolator, distilling the percolate to recover the greater part of the alco- hol, adding water in which a small quantity of carbonate of sodium is dissolved, which precipitates the Emetine together with the insoluble resins, etc. The precipitate is then washed with water acidulated with a little hydrochloric acid, which dissolves the Emetine ; the solution is then filtered through animal charcoal to remove all traces of resin, etc. ; solution of soda is added to the filtrate, which precipitates the Emetine, which is then collected, washed with chloroform, and the solution evaporated without heat to obtain the pure Emetine. Uses. — Emetine is emetic, expectorant, and diaphoretic. The expectorant dose is from -^ to y 1 ^ grain. As an emetic it may be given in from \ to 1 grain doses every twenty minutes until emesis is produced. 95. Gelsemina. G else mine — {Gclscviinia. ) CnH 12 N0 3 . This Alkaloid is the chief medicinal agent of Gelscmium Sem- pc?'vire?is (yellow jasmine), and may be obtained by exhausting the powdered root with alcohol, by means of a water-bath percolator, distilling off most of the alcohol, adding acidulated ALKALOIDES — ALKALOIDS. 117 water to the residue which precipitates the resinous matter and holds the Gelsemine in solution. The solution is then filtered, solution of soda added to precipitate the Alkaloid; the precipitate is then washed with successive portions of ether ; and the etherial solution evaporated without heat to obtain the Gelsemine. Hydrochlorate of Gelsemine is the salt generally prescribed. It is prepared by dissolving the Alkaloid in water acidulated with hydrochloric acid, concentrating by evaporation and crystallizing. Uses. — Gelsemine is an anti-spasmodic, sedative, and some- what anodyne, and must be given cautiously because of its cumulative action. The dose is -^ to -^ grain. 96. Hydrastina. Hydj'astine — [Hydrastia.) C 22 H 33 NO G . The white Alkaloid Hydrastine is recovered from the mother liquor left after the crystallization of salts of berberine, when prepared from hydrastis. It is obtained by diluting the mother liquor with water, evaporating the alcohol, filtering to remove resinous matter, etc., adding ammonia to the filtrate, which precipitates the Alkaloid; dissolving the precipitate in hot alcohol; filtering again through animal charcoal to render colorless ; evaporating the alcoholic solution and crystallizing. Uses. — Hydrastine was formerly a waste product of the manufacture of berberine and its salts (hydrastin), but by the advertising of manufacturers, and being colorless, has come to be used in solution for injections, washes, etc. It is also given internally in doses of -j 1 c - to I grain as a tonic and alterative. 97. Hyoscyamina. Hyoscyamun ( I ' I yoscyamia.) C 17 H 23 N0 3 . I his Alkaloid is obtained chiefly from hyoscyamus, but is found also in belladonna and other species of solanacece. As 118 AI.KALOIDES — ALKALOIDS. the Sulphate of Hyoscyamine is official, the Alkaloid may be prepared from it by precipitating a solution of the salt with soda or potassa alkali, collecting the precipitate, washing with cold water and drying on bibulous paper. For dose, etc., see Hyoscyamiiuc Sulphas. 98. Hyoscyaminae Sulphas, U. S. Sulphate of Hyoscyamine. (C 17 H 23 N0 3 ) 2 .H 2 S0 4 . Hyoscyamus seeds are macerated with gasoline to deprive them of their fixed oil. They are then dried and exhausted with alcohol, by water-bath percolation. The greater part of the alcohol is distilled off and the remainder mixed with water containing tannin in solution. The moist precipitate is then mixed with recently slacked lime, and washed with successive portions of alcohol to dissolve the Alkaloid. The alcoholic washings are then acidulated with dilute sulphuric acid, and agitated with ether to remove coloring matter and oil. The solution is then filtered through animal charcoal, concentrated by evaporation and crystals of Sulphate of Hyoscyamine are produced. Uses.- — This salt has the narcotic and sedative properties of the plant, and is used for sleeplessness, mania, delirium, etc. to X V grain. 99. Hyoscina. Hyoscine — {Hyoscia.) C 17 H 23 N0 3 . This Alkaloid is also obtained from hyoscyamus and has the same chemical composition as hyoscyamine. It is separated from the mother liquor after the removal of the hyoscyamine, and is similar to it in medicinal use. It has recently come into favor as a hypnotic, anodyne, and sedative. ALKALOIDES — ALKALOIDS. 119 ioo. Kairina. Katrine. C 10 H 13 NO.HCl.H 2 O. This is not properly an Alkaloid as its termination would indicate, but the hydrochlorate of an artificial Alkaloid pre- pared from quinoline. It is advertised as a "new quinine," a " substitute for quinine," etc., and is used for the same purposes and in about the same doses as quinine. ioi. Morphina. Morphine — {Morphia.) C 17 H 19 N0 3 .H 3 0. Morphine and its salts are among the most important and most frequently used remedies. Morphine has the distinction of being the first Alkaloid discovered. It was isolated in 1817 by a German apothecary named Serturer, who named it Mor- pJiium. The process for making it was formerly official, but is not repeated in the present pharmacopoeia. We repeat the process with some slight alterations. Opium, sliced, 12 tr. ounces (13^-av.oz.) Water of Ammonia, ... 6 fl. ounces. Animal Charcoal, in fine powder. Alcohol, Distilled Water, each a sufficient quantity. Pour upon the sliced opium 4 pints of boiling water and work with a pestle in a mortar to a smooth paste. After standing a few hours, strain through a coarse sieve, and work what remains in the sieve again with boiling water until it all passes through the meshes; transfer the whole to a water-bath percolator, having first covered the diaphragm with burlap or other coarse cloth, and heat for one hour; then begin to perco- late, adding water and continuing the heat and percolation until the drug is exhausted. Allow the liquid to settle, strain through muslin, evaporate to 6 pints, and filter. To the filtrate add 5 pints of alcohol and afterward 3 fl. ounces of the water of ammonia, mixed with 8 fi. ounces of alcohol. 120 ALKALOIDES — ALKALOIDS. After twenty-four hours pour in the remaining 3 fl. ounces of water of ammonia mixed with 8 fl. ounces of alcohol, and set the liquid aside to crystallize. The alcohol retains the coloring matters, resins, caoutchouc, etc., in solution. The ammonia combines with the natural acids containing morphine, and the Alkaloid morphine is precipitated and may be collected and purified by dissolving the precipitate in two pints of boiling alcohol, filtering while hot through animal charcoal and recrystallizing. Morphine is quite insoluble, requiring 500 parts of boiling water, 100 parts of cold alcohol or 36 parts of boiling alcohol to dissolve it ; it is therefore but little used in medicine, its soluble salts being employed instead. In pharmacy it is used as the basis of the morphine salts, and for making oleate of morphine. Many salts of Morphine are known, but only the three official salts, the acetate, hydrochlorate and sulphate are much used. They are narcotic and sedative, the usual adult dose being ]/% grain. 102. Morphinae Acetas, U. S. Acetate of Morphine — {Acetate of Morphia.) C 17 H 19 N0 3 .HC 2 H 3 2 .3H 2 0. This is prepared according to the process formerly official, as follows : Morphine, in fine powder, .... 480 grains. Distilled Water, 8 fl. ounces. Acetic Acid, a sufficient quantity. Mix the Morphine with the distilled water and carefully add acetic acid drop by drop to the mixture, stirring constantly, until the morphine is neutralized and dissolved. Evaporate the solution by means of a water-bath to the consistence of syrup, and set aside until it concretes. Lastly, dry the salt with a very gentle heat and rub it to a powder. The Br. P. directs the salt to be made by decomposing the hydrochlorate with ammonia, dissolving the precipitate in acetic acid, etc. ALKALOIDES — ALKALOIDS. 121 103. Morphinas Hydrochloras, U. S. Hydrochlorate of Morphine — {Muriate of Morphia?) C 17 H 19 N0 3 .HC1.3H 3 0. The process formerly official in the U. S. P. is as follows: Morphine, in fine powder, .... 480 grains. Distilled Water, 4 fl. ounces. Hydrochloric Acid, a sufficient quantity. Mix the Morphine with the distilled water and carefully add hydrochloric acid to the mixture, drop by drop, constantly stirring it until the Morphine is neutralized and dissolved. Evaporate the solution by means of a water-bath, so that On cooling it may crystallize. Lastly, drain the crystals and dry them on bibulous paper. The Br. P. directs this salt to be prepared from opium in a similar manner, as is employed for making Morphine, subse- quently adding the hydrochloric acid. This is the salt chiefly used in Great Britain. 104. Morphinae Sulphas. Sulphate of Morphine — {Sulphate of Morphia.) (C 17 H 19 N0 3 ) 2 .H 2 S0 4 .5H 2 0. The process formerly official in the U. S. P. is as follows: Morphine, in fine powder, .... 480 grains. Distilled Water, 8 fl. ounces. Diluted Sulphuric Acid, a sufficient quantity. Mix the Morphine with the distilled water, then carefully add diluted sulphuric acid, drop by drop, constantly stirring until the Morphine is neutralized and dissolved. Evaporate III- solution by means of a water-bath, so that on cooling it may crystallize. Lastly, drain the crystals and dry them on bibulous paper. The Br. P. directs the Morphine to be diffused in about twice its weight <>l boiling alcohol, and dilute sulphuric acid added to dissolve it. etc. 122 ALKALOIDES — ALKALOID' Sulphate of Morphine is employed in the U. S. much more than any other salt of Morphine, in fact, the other salts are but little used. Fatal mistakes sometimes occur by dispensing it for quinine, as it so much resembles it in general appearance. It should never be transferred to a shelf or dispensing bottle, but should always be kept in an original ]/% ounce bottle, and distant from the package containing quinine ; all danger will thus be avoided. Other Salts of Morphine. Other salts of morphine are sometimes prescribed ; as the meconate and bi-meconate of Morphine, which are combinations of meconic acid with Morphine ; the bromide or hydrobromate of Morphine, being Morphine combined with hydrobromic acid ; the nitrate, hydriodatc, tartrate, valerianate, etc., combi- nations of Morphine with these acids ; but there is little use for any except the three official salts. 105. Meconidina. Meconidinc. This Alkaloid found in opium is readily obtained by precip- itating a solution of meconic acid with an alkali, washing and drying the precipitate. It is not used in medicine, but is of interest as the base of the meconic principle in opium. 106. Narceina. Narceine — (lVarceia.) C 23 H 39 N0 9 . Another Alkaloid of opium much resembling morphine, but more soluble, is obtained from the mother liquor after the crystallization of morphine. It is narcotic and may be given in y^ to ]/ 2 grain doses. ALKALOIDES — ALKALOIDS. 123 107. Pelletierina. Pellet ierine — (Pum'cine.) C 8 H 15 NO. This Alkaloid from the root bark of Punica Granatum (pome- granate) has recently come into use as a tcsniafuge. It is a liquid obtained by mixing milk of lime with the bark, exhausting with hot water, shaking the percolate with chloro- form, and allowing to evaporate. Dose -^ to -^ grain. Tannate of Pelletierine is the form in which it is usually administered for removing tape worm, the dose being ^ to 2 grains. 108. Physostigmina. Physostigm ine — Eserine. C 15 H 21 N 3 2 . The active principle of calabar bean (Physostigma) is obtained by exhausting finely powdered calabar bean with alcohol by means of the water-bath percolator, distilling off most of the alcohol of the percolate, adding water to the residue and shaking with ether, which dissolves the Alkaloid. The ether is allowed to evaporate and the Alkaloid is obtained in crystals. Uses. — Physostigmine, which is more frequently called Eserine, is a powerful sedative poison, the dose being ¥ J ¥ to ,;'„ grain. 109. Physostigminae Salicylas, U. S. Salicylate of Physostigmine or Eserine. C 1B H 21 N 3 3 C 7 H fl 3 . This official salt may be prepared by adding two parts of Physostigmine to a .solution of one part of salicylic acid in 35 parts of boiling water, and allowing to crystallize on cooling. Uses. -Tin's salt is used in solution to contract the pupil of the eye, and internally as a sedative in doses of from T \^ to 2 ' - errain. 124 ALKALOIDES — ALKALOIDS. I io. Pilocarpina. Pilocarpine — (Pilocarpina.) This is the chief medicinal constituent of the leaves of Pilo- carpus pcnnatifolins (jaborandi). It is obtained by exhausting the drug with alcohol by the water-bath percolator, distilling off most of the alcohol from the percolate, adding water and soda or potassa alkali, collecting the precipitate, washing with chloroform, and evaporating the solution. This produces Pilocarpine, an uncrystallizable Alkaloid. Uses. — Pilocarpine is a diaphoretic and sialogogue. Dose, in. Pilocarpine Hydrochloras, U. S. Hydrochlorate of Pilocarpine. CnH 16 N 3 3 .HCl. This is prepared by adding the Alkaloid Pilocarpine to dilute hydrochloric acid until it is neutralized or until no more will dissolve. The solution is then concentrated by evaporation and allowed to crystallize. Lastly, the crystals are drained and dried on bibulous paper. Uses. — The salt is used for the same purposes as the Alka- loid, and its solution is often employed hypodermically. Dose, yi to % grain. 112. Pyridina. Pyridine. C 5 H 5 N. This liquid Alkaloid was formerly obtained from bone-oil and more recently from coal-tar. It is the first member of the Pyridine series, and consequently forms the basis of many very important substances. It has been suggested that all the Alkaloids are built up by derivation from Pyridine hydrides. It has no medicinal use. ALKALOIDES — ALKALOIDS. 125 113. Quinidina. Quinidine — Quinidia. ^20^24^ 2^2* This Alkaloid may be obtained by decomposing its sulphate (which is recovered from the mother liquors after the crystalli- zation of sulphate of quinine) with water of ammonia or other alkaline solution, washing the precipitate on a filter and drying. The Alkaloid is seldom used except for making elixirs. 114. Quinidinse Sulphas, U. S. Sulphate of Quinidine — {Sulphate of Quinidia) (C 20 H 24 N 2 O 2 ) 2 H 3 SO 4 .2H 3 O. This salt is obtained from the mother liquors from which sulphate of quinine has been removed by crystallization. It differs from sulphate of quinine by being much more soluble, containing a smaller percentage of H 3 0, and by being dextro- gyre while quinine is lsevogyre. It is sometimes called dextro- quinine. Medicinally, it is equal to quinine as an anti-periodic and anti-pyretic, but not as a tonic. The dose is from 1 to 20 grains. 115. Quinina. Quinine — Quinia. C 30 H 34 N 2 O 3 . 3 H 2 O. The Alkaloid Quinine is but little used in medicine on account of its insolubility as compared with its salts. In phar- macy it is frequently directed for making preparations in which the salts are objectionable, as some of the elixirs, syrups, etc., and for making oleate of Quinine. It may readily be prepared from the sulphate or other salts of Quinine by adding to their acid solution water of ammonia or other alkaline solution just sufficient to decompose the salt and precipitate the Alkaloid. The precipitate is then washed On a filter with Cold water and cart: full)' dried. 126 ALKALOIDES — ALKALOIDS. Uses. — Quinine and its salts are tonic, anti-periodic, and anti-pyretic. The dose of the Alkaloid and most of its salts is from I to 20 grains according to circumstances. It is need- less to remark that preparations of Quinine are the most valu- able and the most generally used of any medicines. 116. Quininae Bi-Sulphas, U. S. Bi-sulphate of Quinine. C2 0^24N 2 OoH 2 SO 4 .7H 2 O. This salt is prepared by adding to Sulphate of Quinine mixed with eight times its weight of water, sufficient sulphuric acid to dissolve it ; concentrating the solution by evaporation and allowing to crystallize; then draining and drying the crys- tals on bibulous paper. It is much more soluble — requiring but ten parts of cold water to effect its solution — and contains about one-eighth less of the Alkaloid than the Sulphate of Quinine, but otherwise it does not differ from it in general use, properties and dose. 117. Quininae Hydrobromas, U. S. Hydrobromate or Bromide of Quinine. C 20 H 24 N 2 O 2 HBr.2H 2 O. This may be most readily made by decomposing 40 parts of Sulphate of Quinine dissolved in 10 times its weight of hot alcohol, with 1 1 parts of bromide of potassium dissolved in 3 times its weight of water. The sulphuric acid combined with the Quinine unites with the potassium, forming sulphate of potassium, which crystallize and the bromide unites with the Quinine in the remaining solution, which is concentrated until crystals of Hydrobromate of Quinine are formed. The uses and doses are similar to other quinine salts. 118. Quininae Hydrochloras, U. S., Br. Hydrochlorate or Muriate of Quinine. C 20 H 24 N 2 O 2 HC1.2H 2 O. This may be made in the same manner as Sulphate of Qui- nine, using hydrochloric instead of sulphuric acid, or by ALKALOIDES — ALKALOIDS. 127 decomposing Sulphate of Quinine with chloride of barium in the same manner as is directed for preparing Hydrobromate of Quinine ; or by dissolving the Alkaloid Quinine with diluted hydrochloric acid, concentrating the solution and crystallizing. The uses and doses are similar to the Sulphate of Quinine, but it is very much more soluble, making it more desirable for many purposes. It is the only Quinine salt except the Sul- phate that is recognized by the British Pharmacopoeia. 119. Quininae Sulphas, U. S., Br. Sulphate of Quinine — {Sulphate of Quinia.) This is the best known and most extensively used of any of the salts of Quinine. It is popularly known and called for as "Quinine," and may be generally dispensed when "Quinine" is called for. It is less desirable in many respects than the Hydrochlorate or Bi-sulphate of Quinine, but has the advan- tage of being well known and therefore stands at the head of the Quinine salts. It is made from cinchona bark on a large scale by manufac- turers of chemicals in this country and in Europe, and forms a very important article of commerce. Manufacturing chemists who prepare it have, each, their special processes which produce it, varying slightly from each other in general appearance ; but medicinally and chemically they are the same. A process for making it was formerly official in the U. S. P., but was not repeated in the 6th revision. It is given here for convenient reference : Yellow Cinchona, in coarse powder, 48 troyounces. Hydrochloric Acid, 3^ troyounces. Lime, in fine powder 5 troyounces. Animal Charcoal, in fine powder. Sulphuric Acid. Alcohol. Water. Distilled Water, of each a sufficient quantity. 128 AI.KALOIDES — ALKALOIDS. " Boil the cinchona in 13 pints of water mixed with % of the hydrochloric acid, and strain through muslin ; boil the residue twice successively with the same quantity of water and acid as before, and strain. Mix the decoctions, and, while the liquid is hot, gradually add the lime, previously mixed with two pints of water, stirring constantly until the Quinine (Alkaloid) is completely precipitated. Wash the precipitate with distilled water, and having pressed, dried and powdered it, digest it in boiling alcohol. Pour off the liquid and repeat the digestion several times until the alcohol is no longer ren- dered bitter. Mix the liquids and distill off the alcohol until a brown viscid mass remains. Upon this, transferred to a suitable vessel, pour 4 pints of distilled water, and having heated the mixture to the boiling point add as much sulphuric acid as may be necessary to dissolve the Quinine. Then add \y 2 troyounces of animal charcoal, boil the liquid for two minutes, filter while hot and set it aside to crystallize. Should the liquid before filtration be entirely neutral, acidulate it very slightly with sulphuric acid. Should it, on the contrary, change the color of litmus paper to a bright red, add more animal charcoal. Separate the crystals from the liquid, dis- solve them in boiling distilled water, slightly acidulated with sulphuric acid, add a little animal charcoal, filter the solution and set it aside to crystallize. Lastly, dry the crystals on bibulous paper with a gentle heat and keep them in a well- stopped bottle." Our own process differs from this by exhausting the drug with alcohol by means of the water-bath percolator without using the hydrochloric acid, distilling most of the alcohol, adding water and precipitating the Quinine with water of ammonia or solution of soda, washing the precipitate with hot alcohol, and proceeding as directed in the former official formula. Quinine Sulphate is soluble in 740 parts of cold or 30 parts boiling water ; in 65 parts cold or three parts boiling alcohol ; is precipitated by soluble alkalies,but redissolved by an excess of alkali. Uses. — Sulphate of Quinine is atonic antiperiodic and anti- pyretic ; its uses are too well known to require further mention. ALKALOIDES — ALKALOIDS. 129 The dose is from I to 20 grains. It is given in powders, pills, capsules, mixtures, elixirs, syrups, etc. 120. Quininae Valerianas, U. S. Valerianate of Quinine. C20^24N 3 O 3 C 5 H 10 O 2 .H 3 O. This may be made by decomposing a solution of Sulphate of Quinine with water of ammonia, washing the precipitate, dis- solving it in valerianic acid dissolved in a large quantity of water, and crystallizing. It is rarely used because the quantity of valerianic acid which it contains is too small to be of much medicinal value. Other Salts of Quinine. The foregoing are all the salts of Quinine official in the U.S. P., but many other salts are made and sold by manufacturing chemists ; they are, however, but little used, and the processes for making them are not different from those already given in the preceding pages ; being chiefly made by decomposing a solution of the Sulphate, and recombine it with the acid desired. " Hospital Quinine " is a mixture of the sulphates of cin- chonidine, quinidine and Quinine, generally containing about 50 per cent, of Quinine in combination. " Dextro-Quinine" and " Cincho-Quinine" are preparations containing Quinidine mixed with cheaper salts of cinchona. " Sweet Quinine," which had at one time a great run, proved to be a mixture of the cheaper salts of cinchona with powdered glycyrrhizin. Several other preparations claiming to be substitutes for Quinine arc made up of the cheaper salts of cinchona bark combined with other substances ; but since low prices have ruled for Sulphate of Quinine there is little demand for them. 121. Quinolina. t 'It incline — Lcucolinc — Quinoline. C 9 H 7 N. A liquid Alkaloid obtained from coal tar, closely related in chemical composition and action to the Cinchona Alkaloids. 130 ALKALOIDES — ALKALOIDS. It is the first member of the Leucoline or Chinoline series, which have been much experimented upon for the artificial production of Quinine. The Tartrate of Chinoline is sometimes used in medicine for the same purpose as Quinine, and given in doses of from 4 to 16 grains. 122. Sanguinarina. Sanguinarine, C 19 H 17 N0 4 . This Alkaloid may be made by exhausting Sanguinariawith alcohol, by means of the water-bath percolator, distilling off most of the alcohol, adding water and solution of soda to pre- cipitate, washing the precipitate with hot alcohol, filtering through animal charcoal, concentrating and crystallizing. It is white, but yields very bright red salts with acids. Nitrate of Sanguinarine and Sulphate of Sanguinarine have been introduced by manufacturing chemists, and are quite favorably received by practitioners. Uses. — Sanguinarine and its salts are used in bronchitis, pneumonia and laryngitis in doses of -^ to -^ grain. 123. Strychnina, U. S., Br. Strychnine — (Strychnia.) C 21 H 22 N 2 2 . This poisonous Alkaloid may be prepared by the former U. S. P. process, or by the 1885 Br. P. method. As the latter is later authority, and fully as concise, we repeat it (slightly altered) here : Nux Vomica, in fine powder, .... 16 oz. av. Acetate of Lead, 180 grains. Solution (Water) of Ammonia, Rectified Spirit, Distilled Water, of each a sufficiency. Macerate the powder for 12 hours with two pints of the spirit and one of water, by gentle heat ; transfer to the water- ALKALOIDES — ALKALOIDS. 131 bath percolator, heat and percolate with two parts of spirit to one part of water until the drug is exhausted. Distill off the spirit, evaporate the residue to about 1 6 fl. ounces and filter when cold ; then add the acetate of lead previously dissolved in dis- tilled water, so long as it occasions any precipitate; filter; wash the precipitate with 10 ounces of cold water, adding the washings to the filtrate ; evaporate the clear liquid to eight fl. ounces and when it has cooled add the ammonia in slight ex- cess, stirring thoroughly. Let stand for 12 hours, collect the precipitate on a filter, wash it once with a few ounces of cold water, dry it by gentle heat, and boil it with successive por- tions of rectified spirit till the washings are no longer percep- tibly bitter. Distill off most of the spirit, evaporate the resi- due to about y 2 ounce and set aside to cool. Cautiously pour off the yellowish mother liquor (which contains the brucine) from the white crust of Strychnine which adheres to the vessel. Wash the crust on a filter paper with a mixture of two parts of rectified spirit and one of water till the washings cease to become red on the addition of nitric acid ; finally, dissolve it by boiling with an ounce of rectified spirit and set aside to crystallize. More crystals may be obtained by evaporating the mother liquor. Brucine — Co 3 H 20 N 2 O 2 — may be recovered from the yel- lowish mother liquor which is poured off (see above) by concentration and crystallization. Uses. — Strychnine and its salts are among the most valuable tonics we possess. It is given particularly in nervous exhaus- tion, and as a general tonic combined with other remedies. Dose, yfo to ,,'„ grain. 124. Strychninae Sulphas, U. S. Sulphate of Strychnine — (Sulphate of Strychnia.) This may be prepared by dissolving Strychnine in diluted Sulphuric acid, concentrating the solution and crystallizing. The crystals are then drained and dried on bibulous paper. It is the most used of any of the strychnine salts because of its 132 ALKALOIDES — ALKALOIDS. stability and ready solubility. It is used in pills, mixtures, elixirs, syrups, etc., alone and in combination with other medi- cines. The dose is the same as the Alkaloid, from T -i T to -^ grain. Other Salts of Strychnine. Many other salts of Strychnine are made by manufacturing chemists ; but the foregoing are all that are official or that are much used. If desired, others can be made in the same man- ner as the Sulphate by using other dilute acids in place of sulphuric. 125. Thallina. Thalline. A new Alkaloid derived from Peruvian bark, and recently discovered by Prof. Straup, of Vienna. It possesses remark- able antipyretic properties, and is very prompt and efficient in its action. The sulphate is the salt most frequently used ; the dose being from 2 to 5 grains. The tannate and tartrate are also prescribed. Antipyrin and Antifebrin are proprietary antipyretics, lately introduced, similar in action to thalline. 126. Trimethylamina. Triniethylamine. (CH 3 ) 3 N. This Alkaloid is isomeric with Propylamine, and its solution in water is furnished and used as propylamine. True propyl- amine is not used in medicine. Trimethylamine is made from herring-pickle by distillation with lime, the distillate being neutralized with hydrochloric acid and evaporated and the saline residue treated with abso- lute alcohol which dissolves out the Alkaloid and leaves the chloride of ammonium undissolved. The alcoholic solution is then distilled, the residue dissolved in water and again care- fully distilled with lime, the distillate being the liquid Alkaloid. This Alkaloid is also obtained from the residues left in the ALKALOIDES — ALKALOIDS. 133 preparation of beet sugar; from ergot, cod-liver oil, guano and other substances. Hydrochlorate of Trimethylamine, which is also sold under the name of Chloride or Hydrochlorate of Propylamine, is obtained by neutralizing Trimethylamine with hydrochloric acid, evaporating and crystallizing. Uses. — The hydrochlorate is used in articular rheumatism and gout. The dose is from 2 to 3 grains, generally given in elixir or syrup. 127. Veratrina, U. S., Br. Veratrine — ( Veratria^) An Alkaloid or mixture of Alkaloids obtained from the seeds of cevadilla {asagrcea officinalis) by exhausting them with alcohol by means of the water-bath percolator, recovering most of the alcohol by distillation, adding water, filtering to remove resins, etc., adding solution of potassa or ammonia to the filtered liquid, collecting the precipitate, dissolving it in alco- hol, filtering through animal charcoal, concentrating and crystallizing. Uses. — It is used externally in liniments, ointments, and applications for neuralgia, rheumatism, etc. It is very poisonous. Other Alkaloids. The foregoing Alkaloids and their salts are the chief natural Alkaloids now employed in medicine, but others are being constantly brought to notice, and finding use and favor as medicinal agents. Quite a number of artificial Alkaloids are now being introduced, and finding new application in medicine and the arts. The coal tar bases, aniline, pyridine, toluidine, etc., and their derivatives arc extensively used in the arts, besides forming the bases of many of the artificial Alkaloids, which are now made. The chemist in his laboratory is now able to prepare, by synthesis, several of the Alkaloids, either identical with or 134 ALLYL. closely resembling the natural ones, and it is not improbable that ere long most of the valuable Alkaloids that are now obtained from rare or expensive drugs may be reproduced in the chemist's workshop from worthless substances, that have heretofore been waste products. It is not expedient to give in detail the complex operations by which artificial Alkaloids are produced, but it may be stated in general that they are mostly made, either by converting one Alkaloid of a drug into another by supplying or abstracting some portion of its ele- ments, or by substituting atoms of one element for another in the complex molecules of organic bases. Other Alkaloids will be noticed under other headings. ALLYL. A cry I — Propylenyl. The radical of the essential oils containing sulphur is called Allyl. The plants or oils containing this radical combined with sulphur have peculiar pungent, penetrating odors which cannot be mistaken. Asafcetida, scurvy grass, cress, garlic, leek, horseradish, radish, shepherd's purse, wallflower, mustard, onion, nasturtium, and many other less familiar plants owe their peculiar odors and pungency to combinations of the Allyl radical with some form of sulphur. The Allyl and glyceryl radicals are isomeric, being identical in composition, but the former is univalent and the latter trivalent. 128. Allyl Hydrate. C 3 H 5 HO. — {Allyl Alcohol:)— By uniting with the elements of water Allyl forms a hydrate or alcohol which boils at 96°C. It has no use at present in pharmacy. 129. Allyl Sulphide. (C 3 H 5 ) g S.— {Artificial Oil of Garlic.)— This is artificially produced by decomposing Allyl Iodide with an alcoholic solution of sulphide of potassium. Its composition is the same as the natural Volatile Oil of Garlic. 130. Allyl Sulphocyanate. C 3 H 5 CNS.— {Artificial Oil of Mustard) — This is prepared by distilling Allyl Sulphate with potassium isothiocyanate, or by gently heating a mixed alcoholic solution of sulphide of Allyl and bichloride of mercury, with sulphocyanide of potassium. It is identical in> ALOE — ALOES. 135 composition with the natural volatile oil of mustard, which is chemically Allyl isothiocyanate. The volatile oil of mustard is used in some liniments and pain relievers. Its vapor is very irritating, and care must be used in dispensing it. It should be very much diluted when employed. ALOE— ALOES. As found in the market Aloes consists of the inspissated juice of the leaves of several varieties of Aloe found in Africa. The U. S. P. recognizes only the variety produced from Aloe Socotrina; the Br. P. directs both Barbadoes and Socotrine Aloes, while the G. P. names Cape Aloes, which includes a variety of different species native of the Cape of Good Hope. The various species are all more or less used in pharmacy, the Barbadoes and Socotrine being chiefly employed for man and the Cape Aloes for horses and cattle. The fleshy leaves of the Aloe are cut off near their base and their juice allowed to drain into troughs or vessels. The col- lected juice is then evaporated to the consistence of an extract and run into boxes, kegs or gourds, in which shape it is brought to the market. Aloes is a well-known and much-used purgative, being familiarly known to the household as " Picra." It is the active ingredient in most patent and cathartic pills. In small doses, i to 2 grains, it is a tonic, stomachic, and is the chief ingredient of several " bitters " which have been extensively sold. The laxative dose is 2 to 3 grains, and the dose as an active purgative is 10 to 13 grains. Various preparations of Aloes will be found under their proper headings, as extracts, pills, powders, tinctures, wines, etc. 131. Aloe Purificata, U. S. Purified Aloes. Aloes, 100 parts or 10 ounces av. Alcohol 15 parts or 2 fl. ounces. Heat the Aloes by water-bath until it is completely melted, then add the alcohol and having stirred the mixture thoroughly 136 ALUMINIUM. strain it through a fine sieve which has just been dipped into boiling water. Evaporate the strained mixture by means of a water-bath, constantly stirring until a thread of the mass becomes brittle on cooling. The object of purifying the Aloes is to remove foreign sub- stances, such as sticks, stones, dirt, and other impurities which, by the carelessness in making it, have been introduced. Its properties and uses are the same as Aloes. It is only official in the U. S. 132. Aloin, Br. C 16 H 18 7- " A crystalline substance extracted from Aloes by solvents and purified by recrystallization. As obtained from the differ- ent varieties of Aloes, the products differ slightly, but their medicinal properties are similar." Br. Aloin appears to be the active or cathartic principle of Aloes. It is obtained by treating Aloes with acidulated boil- ing water, which dissolves the Aloin and resinous matter. After standing for some hours to cool the liquid is poured off from the resin and evaporated to the consistence of syrup. When cool, crystals of Aloin form, which may be purified by repeated recrystallization from hot alcohol. The laxative dose is from Trr to T grain, the cathartic dose |- to 2 grains. It is considerably used, in combination with other medicines, in "little liver pills." ALUMINIUM. Symbol, Al ; Atomic weight, 27.3 ; Sp. gr. 2.56. Aluminium is a metal element which exists in nature in com- bination with silicic acid in clays and rocks. In this form it is very abundant, but because of the difficulty of separating it from its combinations it is quite expensive. It was first obtained from the chloride by Wohler in 1828, but was known only as a laboratory product until 1858, when Deville improved the methods of producing it so that it could be manufactured for commercial purposes ; recent processes have, however, ALUMINIUM. 137 been introduced by which it can be furnished at a much lower price, and it will be much more employed in the arts than formerly. It is a very light, silver-white metal, strong, ductile, malleable, and non-corrosive, admirably fitting it for many use- ful and ornamental purposes. The only use to which the metal is applied in the business of the pharmacist is for making grain weights, but its salts unite with the salts of the alkali metals, to form double salts called alums, which are con- siderably used in medicine and pharmacy, and extensively employed in dyeing and other arts. Besides the double salts, it forms single salts with many of the acids, though they are but little used, the hydrate and sulphate only being official. From its wide distribution in nature, its importance and usefulness in the arts, and the possibilities of its application, it is now called the "Metal of the Future." Aluminium Bronze is an alloy considerably used for making ornaments, mounting instruments, etc. It is composed of 9 parts of copper and one of aluminium. Kaolin or China Clay ( Al 3 3 .2Si0 3 +2H 3 ) is a hydrated silicate of Aluminium oxide, found in nature, and used for mak- ing china-ware, crockery, etc. It is sometimes used in pharmacy. 133. Alumen, U. S., Br. Alum. K 3 A1 3 (S0 4 ) 4 ,2 4 H 3 0. This is the official potassa-alum (Aluminii et Potassii Sul- phas). The alum of commerce is ammonia-alum (NH 4 ) 3 A1 3 (S0 4 ) 4 . It is to be regretted that the official salt is not the same as the commercial, for, on account of their difference, the official salt is seldom used, the commercial alum being sup- plied whenever it is directed. The potassa-alum is prepared by treating alum-clay with sulphuric acid to form Aluminium Sulphate, then adding potassium sulphate, which unites to form the double salt. Ammonia-alum is made in a similar way, ammonium sulphate- being used instead of potassium sulphate. Alum is a powerful astringent, and is used externally as a 138 ALUMINIUM. wash, styptic, etc. It is also given internally as an astringent and in croup as an emetic, and is much used as an astringent injection and gargle. Potassa-alum is soluble in about 10 parts of cold water, while ammonia-alum requires about 16 parts. Alum Curd.— Alum in the form of curd, made by rubbing white of egg with a lump of alum until it is coagulated, or by mixing half a teaspoonful of powdered alum with the white of one egg, is considerably used as a " poultice " for inflamma- tion, especially of the eye. Alum Whey is a domestic remedy, made by boiling a large teaspoonful (60 grains) of powdered alum with a glassful (about 10 fl. ounces) of milk, and straining when cool. The liquid is taken in doses of a wineglassful for looseness of the bowels, etc. 134. Alumen Exsiccatum, U. S., Br. Dried or "Burnt" Alum. K 3 A1 2 (S0 4 ) 4 . This is officially made by exposing alum for several days to a temperature of about 8o° C. (176 F.) until it has thoroughly effloresced, and then placing it in a porcelain capsule and grad- ually heating it to a temperature of 200° C. (392 F.) and continuing the heat until the mass becomes white and porous. As found in commerce it is usually made from commercial ammonia-alum, by melting it in an iron kettle and continuing the heat until the water of crystallization has entirely evap- orated. In a domestic way it is made by putting a lump of alum on a hot stove and letting it remain until it is dry. With this, as with the official alum, potassa-alum is seldom employed to make it, ammonia-alum being used instead. As this is simply alum deprived of its water of crystalliza- tion it has the same general properties as alum, but is much more powerful. It is chiefly used as an escharotic for remov- ing " proud flesh " or other morbid growths. It is also used for hemorrhages, particularly of the nose, and of the gums after drawing teeth. It is generally used in the form of dry powder. ALUMINIUM. 139 135. Aluminii Hydras, U. S. Hydrate of Aluminium — (Hydrated Alumina?) Al,(HO),. This is a white light powder, somewhat resembling magnesia, made by precipitating a saturated solution of alum with a solu- tion of carbonate of sodium ; the proportions are as follows : Alum, 11 parts or ounces. Carbonate of Sodium 10 parts or ounces. Distilled Water, a sufficient quantity. Dissolve each salt separately in 150 parts (or about 10 pints) of distilled water, filter the solutions and heat them to boiling, then having poured the hot solution of carbonate of sodium into a capacious vessel, gradually pour in the hot solution of alum, with constant stirring, and add about 100 parts or 6 pints of boiling distilled water. Let the precipitate subside, pour off the water and wash it well with fresh water as directed for washing precipitates (page 44), then dry at a temperature not exceeding 40 'C. (104 F.) and reduce to a uniform powder, which is the hydrate. The Hydrate of Aluminium is an absorbent and antacid, and is given in doses of from 2 to 5 grains in irritation of the stomach, etc. Externally it is used for covering inflamed sur- faces to prevent chafing, etc. It is also used as an ingredient in face-powders and liquid cosmetics. Alumina. — Oxide of Aluminium (A1 2 3 .) — This is the most abundant of the earths, the chief constituent of clay. It may be prepared by heating the hydrate to a white heat in a covered crucible. The Hydrate and Oxide of Aluminium readily dissolve in acids forming soluble salts. 136. Aluminii Sulphas, U. S. Sulphate of Aluminium. .\1.,(S() 4 ),.i8H 2 0. This may be made by dissolving Hydrate of Aluminium to saturation in diluted sulphuric acid by the aid of heat, evap- 140 ALUMINIUM. orating the solution and crystallizing or granulating by stirring until dry. It is but little used internally, but in the form of a weak solution (i ounce to I quart) is used as an astringent injection and cleansing wash for ulcers, etc. A saturated solu- tion is a powerful escharotic and astringent, and may be used for the same purposes as " burnt " alum when it cannot well be applied. Other Salts of Aluminium. Besides the foregoing official Salts of Aluminium, it com- bines with other acids and elements forming salts sometimes used in pharmacy, medicine and the arts. 137. Aluminium Acetate — A1 3 6C 3 H 3 3 . — Made by dissolving Alu- minium Hydrate in acetic acid to saturation, evaporating and crystallizing. It is chiefly used for dyeing and calico printing as a mordant, but is some- times used in medicine for diarrhoea and as a preservative for animal tissues in the form of injection. 138. Aluminium Chloride — A1 3 C1 6 . — By dissolving Aluminium Hydrate in hydrochloric acid to saturation, evaporating carefully and crystallizing ; also by sublimation. Chloralum. — An impure solution of Aluminium Chloride called Chloralum, is made by dissolving one part of aluminium hydrate in five parts of com- mercial hydrochloric acid. It is used for disinfecting. 139. Aluminium Bromide — Al 3 Br 6 . — By passing vapor of bromine over a heated mixture of alumina and carbon. Sometimes used as an antiseptic. 140. Aluminium Iodide — A1 3 I 6 . — By heating Aluminium and iodine together in closed tubes. 141. Aluminium Nitrate — Al 3 (N0 3 ) G .i8H,0. — By dissolving Alu- minium Hydrate in nitric acid to saturation, filtering, concentrating and crystallizing. 142. Aluminium Phosphate — A1 3 (P0 4 ) 3 . — By mixing a neutral solution of Alumina with a solution of sodium phosphate and collecting the pre- cipitate. 143. Aluminium Tannate. — By triturating 1 part of Hydrate of Alu- minium and 2 parts of tannic acid with sufficient water to make a mixture the consistence of syrup, and then evaporating to dryness by a heat not over 120 F. It is used in dysentery, hemorrhage, etc., in doses of 3 to 12 grains. Other Salts of Aluminium may be prepared with other acids and elements, but the foregoing are all that are generally known. AMMONIUM. 141 AMMONIUM. Symbol, NH 4 ; Atomic weight, iS. A hypothetical metal, the analogue of potassium and sodium. Although it is not classed with the elements, it has the same characteristics as the alkali metals. The metal Ammonium has not yet been authoritatively isolated, but it is reported that Weyl succeeded in obtaining it as a dark-blue liquid, having a metallic lustre. Its composition is therefore only known by its characteristics in its compounds, which correspond with the chemical formula (NH 4 ) assigned to it. It is an univalent radical like potassium or sodium and its compounds or salts closely resemble them. The Salts of Ammonium are mostly colorless and very soluble in water, they are volatilized at high temperatures, and when heated with the hydrates of potassium, sodium, or cal- cium are decomposed with evolution of ammonia gas. The derivatives and Salts of Ammonium are extensively used in pharmacy, medicine, and the arts, the commercial basis of them being chiefly the waste " ammoniacal liquor" of gas works, which is neutralized either with sulphuric acid, forming sulphate of ammonium, or with hydrochloric acid, forming crude chloride of ammonium (sal-ammoniac), which may be converted into any of the ammonium compounds. Ammonium Amalgam. — The nearest approach to the metal Ammonium is Ammonium Amalgam, which is made by dissolving potassium in mercury and adding a strong solution of ammonium chloride to it. It is a spongy metallic substance, which as soon as formed begins to decompose into ammonia, mercury and hydrogen. 144. Ammonia. Ammonia Gas — Hydrate of Ammonium. NH 3 . Gascons Ammonia was first made known by Priestley in 1785. It is known by its peculiar odor and by its property of 142 AMMONIUM. restoring the color of blue litmus which has been reddened by acids, or by forming a white cloud with the vapor of hydro- chloric acid. In pharmacy its solution in water (which is known in the United States as water of ammonia and in Great Britain, France and Germany as solution of ammonia) is the only form in which it is available ; but in the arts, gaseous ammonia is considerably employed. It is produced in nature by the decomposition of animal and some vegetable substances and is mainly supplied to commerce from the waste products of gas manufacture. It is retained for use in the form of some of its stable salts with acids. It is strongly alkaline, and is sometimes called animal alkali, volatile alkali, etc. It unites with nearly all acids to form stable salts, and dis- solves freely in water — I volume of water dissolving nearly 700 volumes of the gas — but it escapes freely from its aqueous solution when exposed ; hence the penetrating odor of water of ammonia. In the form of gas it is used by inhalation from its solution as a quick stimulant and restorative for syncope, collapse, etc., and as a domestic remedy for headache and many other ailments. Amidogen — NH 2 .— This is a hypothetical body composed of one atom of nitrogen and two of hydrogen. As its name indicates, it is the generator of amides, which it forms by com- bining with other bodies. Amides are compounds derived from Ammonia by replacing one or more of its atoms of hydrogen by an acid radical. All the known Amides are white crystalline solids, many of them having both acid and basic properties. They include most of the non-volatile alkaloids (see page 98) and the Ammonia derivatives of the haloid and ethereal salts, etc. They are known as monamides, diamides and triamides according to their formation and combination. Amines are compounds derived from Ammonia by replacing one or more of its atoms of hydrogen with a basic radical. They consist of the volatile alkaloids (see page 98), the arti- ficial alkaloids, the ammonia derivatives of the alcohol radi- cals and other hydrocarbons, etc. They are known as AMMONIUM. 143 monamines, diamines, or triamines according as the hydrogen is displaced from a single, double, or triple molecule of Ammonia. Alkamides are Ammonia compounds intermediate between amines and amides, containing both acid and basic radicals. 145. Aqua Ammoniae. Water of Ammonia, U. S. — Solution of Ammonia, Br. Although this preparation is properly included under the heading AQU.E or LIQUORES, it is also given here because it is the basis of many of the Salts of Ammonium. The process of the 1870 U. S. P. was to mix muriate of ammonia (ammonium chloride) in small pieces with milk of lime in a retort connected with a cooled receiver by means of a glass tube extending beneath the surface of distilled water con- tained in the receiver. Heat being then applied the lime is converted into chloride of lime, liberating the ammonia gas which is distilled and dissolved in the water contained in the receiver. The official strength of the U. S., Br. and German, water, liquor or solution of ammonia is 10 per cent, by weight of the gas. Its sp. gr. is 0.960. In German pharmacy it is often pre- scribed by its Latin name, "Liquor Ammo nit Caustici." It is supplied by manufacturers in carboys, and marked by some 16 and by others F.F.F. or 3 F. Other manufacturers mark the 20 ammonia F.F.F. or 3 F., so it will be seen that considerable confusion exists in regard to the F.'s, and they should never be taken as the standard of strength of the solution, the degree marks, only, being reliable. In pharmacy both the 10 percent, and the stronger solutions arc used in making the official preparations, and in general use other strengths arc employed ; for druggists buy of manufac- turing chemists water of ammonia varying all the way from 6 to 28 per cent, or more of the gas — the most frequently sold being the " FFF " or 20 Baum6, sp. gr. 0.933, containing 17^ per cent, of gas. To reduce the 20 or "FFF" ammonia to 144 AMMONIUM. the official io per cent, water of ammonia mix 16 ounces av. with 12 ounces av. of distilled water. To reduce the 28 per cent, or stronger water of ammonia to the 10 per cent, strength, mix 16 ounces av. with 28|- ounces av. of distilled water. Uses. — In medicine water of ammonia is used externally as an application in the form of liniments, mixtures, etc., as a stimulant and counter-irritant for rheumatism, neuralgia, lame- ness, etc. Internally it is given very largely diluted as an antacid and stimulant, in doses of from 5 to 30 drops. In the industrial arts and manufacturing of chemicals ammonia is extensively used either in the form of gas, solution, or salts. 146. Aqua Ammoniae Fortior. Stronger Water of Ammonia, U. S. — Strong Solution of Ammonia, Br. The U. S. official Stronger Water of Ammonia contains 28 per cent, of ammonia gas by weight, sp. gr. 0.900, and is marked 26 . The Br. Strong Solution of Ammonia contains 32.5 per cent, of the gas by weight, sp. gr. 0.891. There is no corresponding official German solution. It is prepared in the same manner as the 10 per cent, solu- tion, except that a greater percentage of gas is dissolved in the water. Stronger Water of Ammonia is frequently employed as a vesicant and caustic, but is seldom given internally. Ammonium Salts. Ammonium forms salts with nearly all the mineral and vegetable acids. They are generally colorless and very soluble in water. A few only are official in the U. S., less in the Br., and still less in the G. P. Of those unofficial in the U. S. P. but few are used in medicine or pharmacy. The following are the official salts : AMMONIUM. 145 147. Ammonii Benzoas. Benzoate of Ammonium. NH 4 C 7 H s 2 . Benzoic Acid, 1 ounce av. Water of Ammonia, about, . . . . 1)4 fl. ounces. Distilled Water 2 fl. ounces. Mix the water of ammonia with the distilled water and dis- solve the benzoic acid in the mixture. Evaporate the solution by gentle heat, adding from time to time a little water of ammonia to maintain a slight excess of alkali. Then set aside to crystallize and dry the crystals without heat. Uses. — The Benzoate of Ammonium is somewhat used as a stimulant diuretic in kidney diseases. Dose 5 to 20 grains. 148. Ammonii Bromidum. Bromide of Ammonium. NH 4 Br. This salt may be made by neutralizing hydrobromic acid with ammonia, evaporating the solution and crystallizing; by decomposing bromide of potassium with ammonium sulphate in the presence of alcohol, and by many other processes. Uses. — Bromide of Ammonium is used as a hypnotic and sedative, and is by many preferred to potassium bromide. Dose from 10 to 60 grains or more. \ 149. Ammonii Carbonas. Carbonate of Ammonium — Sal Volatile — Hartshorn — Sesaui- Carbonate of Ammonium. MI.,HC0 3 .NH 4 NH 2 C0 2 . As prepared for commerce the Carbonate of Ammonium is a mixed salt, consisting of one molecule of acid ammonium carbonate and one of ammonium carbamate. It is generally I4(> AMMONIUM. prepared by subliming chloride or sulphate of ammonium with chalk or calcium carbonate and resubliming the product. It is a volatile and pungent ammonia salt — the only one having the odor of ammonia gas. Exposed to the air it soon loses the odor of ammonia and becomes inert, hence it must be carefully preserved in air-tight packages. Uses. — In pharmacy it is used in making aromatic spirit of ammonia, solution of acetate of ammonium and several other preparations and in the preparation of smelling salts. In medicine it is given as a stimulant in doses of 3 to 5 grains, generally in some mucilaginous syrup. It is frequently given combined with expectorants in cough syrup. It is also employed in cleaning compounds and for culinary purposes. 150. Ammonii Chloridum. Chloride of Ammonium — Muriate of Ammonia — Sal Ammoniac. This salt is generally prepared, commercially, from the ammoniacal liquid obtained from gas works, and known as " gas liquor" by neutralizing with hydrochloric acid and subliming the salt thus obtained. It is inconvenient for pharmaceutical use as it comes into market, but may be granulated and puri- fied as follows : Chloride of Ammonium, in small pieces, 20 tr.ounces. Water of Ammonia, 5 fl. drachms. Water, 2 pints. Dissolve the salt in the water by the aid of heat in a porcelain vessel, add the water of ammonia, and continue the heat for a short time, filter the solution while hot and evaporate to dry- ness with constant stirring at a moderate heat until it granu- lates. Uses. — The Chloride of Ammonium is used as a stimulant, especially in cough mixtures, and externally in ''solution," for lameness, etc. The dose internally is from 2 to 10 grains. AMMONIUM. 147 151. Ammonii Iodidum. Iodide of Ammonium. This is made by decomposing a concentrated solution of iodide of potassium with sulphate of ammonium. Sulphate of potassium remains undissolved and Iodide of Ammonium is obtained from the filtered liquid by evaporation and crys- tallization. Uses. — The Iodide of Ammonium is similar to iodide of potassium and is used for the same purposes. It is alterative and resolvent. Dose 2 to 5 grains. 152. Ammonii Nitras. Nitrate of Ammonium. NH 4 2 . Nitrate of Ammonium may be made by adding carbonate of ammonium to nitric acid as long as effervescence occurs, then filtering the solution, concentrating and crystallizing or evaporating until all the water is driven off, when it may then be "granulated " by stirring until cool, or " fused " by allowing to cool without stirring. Uses. — This is sometimes used as a diuretic, but is chiefly employed for the preparation of nitrous oxide or " laughing gas," which is made from it simply by heating the Nitrate of Ammonium and purifying the gas by running through a wash- bottle. 153. Ammonii Phosphas. Phosphate of Ammonium. (NH 4 ) a HP0 4 . Tin's may be made: by adding stronger water of ammonia to phosphoric acid (50 percent., [880,) until slightly in excess, then concentrating the liquid by evaporation and crystallizing. 148 AMMONIUM. A little water of ammonia should be added while evaporating to keep the solution slightly alkaline. Uses. — This is used as a remedy for rheumatism and gout in doses of 1 5 to 30 grains. 154. Ammonii Sulphas. Sulphate of Ammonium. (NH 4 ) 2 S0 4 . The common source of this salt is gas liquor or fetid bone- spirit, which is saturated with sulphuric acid and the salt obtained repeatedly crystallized to obtain pure. It is also made by adding gas liquor to powdered sulphate of calcium, which is decomposed, leaving calcium carbonate precipitated, while the Sulphate of Ammonium remains in solution. The solution is then evaporated and crystallized. Uses. — The Sulphate of Ammonium is used as the basis of most of the ammonium salts and as a source of ammonia gas in making water of ammonia, because of its cheapness. It is not employed in medicine. 155. Ammonii Valerianas. Valerianate of Ammonium. NH 4 C 5 H 9 2 . This salt is prepared by passing dried gaseous ammonia into monohydrated valerianic acid. A process for making it was official in the U. S. P. 1870; but it is generally supplied by manufacturing chemists who have facilities for preparing it. It is chiefly used in pharmacy for making Elixir of Valerianate of Ammonium. Uses. — In medicine Valerianate of Ammonium is employed, usually in the form of elixir or solution, in hysteria, delirium, neuralgia, and nervous diseases. It is a nervine. The usual dose is from 2 to 20 grains. AMMONIUM. 149 Other Salts of Ammonium. Besides the foregoing official Salts of Ammonium, the follow- ing are sometimes used : 156. Ammonium Arseniate — (NH 4 ) 2 ,H,As0 4 . — Made by saturating a concentrated solution of arsenious acid with water of ammonia and allowing to evaporate spontaneously. A soluble salt of arsenic frequently employed in medicine. 157. A mm °nium Bicarbonate — NH 4 HC0 3 . — Add one part of powdered carbonate of ammonium to two parts of water, agitate and decant the liquid, the residue remaining is the Bicarbonate of Ammonium. 158. Ammonium Bichromate — (NH 4 ) 2 Cr 2 7 . — Made by adding chromic acid to stronger water of ammonia to saturation, concentrating and crystal- lizing. 159. Ammonium Borate — 2(NH 4 HB 2 4 ),3H 2 0. — Dissolve one part of boric acid in three parts of warm water of ammonia, 10 per cent., allow to cool slowly and crystallize. Used for the same purposes as borate of sodium or common borax. 160. Ammonium Carbazotate or Picrate. — Add carbazotic (picric) acid to stronger water of ammonia to neutralize, allow to evaporate spontaneously and crystallize. 161. Ammonium Citrate — (NH 4 ) 3 C 6 H 5 7 + 3H 2 0. — Add citric acid to water of ammonia to neutralize, concentrate and crystallize. This assists in dissolving salts of quinine and other salts of alkaloids. 162. Ammonium Fluoride — NH 4 F. — Made by saturating hydrofluoric acid with water of ammonia. 163. Ammonium Formate — NH 4 CH0 2 . — Neutralize formic acid with water of ammonia, concentrate and crystallize. 164. Ammonium Gallate. — Add gallic acid to stronger water of ammonia to saturation, concentrate and crystallize. 165. Ammonium Hydrosulphide or Sulphide — NH 4 HS. — By passing sulphuretted hydrogen gas through water of ammonia a solution may be obtained, or by mixing gaseous ammonia with sulphuretted hydrogen gas at low temperature crystals are formed. 166. Ammonium Hypophosphite.- I \y neutralizing water of ammonia with nypophosphorous acid, concentrating and crystallizing. This is used in com- bination with other hypophosphites in syrups and solutions. 167. Ammonium Molybdate. Made by neutralizing molybdic acid with ammonia. Pho&komofybdate of Ammonium is a compound with phos- phoric a. nl. These salts are used as tests for organic bases, which they pre- cipitate. 150 AMMONIUM. AM VI. 168. Ammonium Nitrite — NH 4 NO„. — To a solution of nitrate of silver add a solution of chloride of ammonium and evaporate the clear solution poured from the precipitate over sulphuric acid to dryness. This is used as a diuretic. 169. Ammonium Oxalate — iNH 4 ) 2 C 2 4 . — To a hot solution of oxalic acid add carbonate of ammonium until neutralized, concentrate the solution and crystallize. It is used in chemistry as a test for calcium, with which it produces a white precipitate soluble in nitric acid. 170. Ammonium Phenylate or Phenylamine is produced in small quan- tities when carbolic acid is heated in sealed tubes with ammonia. It is known in the market as aniline, or "aniline oil," the base of the aniline dyes. See Aniline. 171. Ammonium Salicylate — NH 4 C-H 5 3 . — Add salicylic acid to water of ammonia until neutralized, then evaporate and crystallize. Used in rheumatism aud neuralgia the same as salicylate of sodium. 172. Ammonium Succinate. — Dissolve 1 part of succinic acid in 4 parts of water, neutralize with carbonate of ammonium, in slight excess, evaporate and crystallize. 173. Ammonium Sulphite — NH 4 HS0 3 . — This is made by passing sul- phurous acid gas into an alcoholic solution of ammonia and collecting the precipitate. 174. Ammonium Sulphocyanate — NH 4 CNS. — Neutralize hydrosulpho- cyanic acid with ammonia, or dissolve bisulphide of carbon in alcohol and heat in the presence of water of ammonia, then concentrate by evaporation and crystallize. 175. Ammonium Vanadate. — Neutralize vanadic acid with ammonia, concentrate and crystallize. Many other Ammonium Salts are formed with various acids and acid compounds, but those mentioned are all that are generally used in pharmacy. AMYL. C.H lr The radical of the Amyl series of compounds of which " fousel oil " is the hydrate, is known as Amyl. Its compounds form an interesting series of products, somewhat used in medicine and considerably employed in making artificial fruit flavors. The compounds of Amyl are nearly all prepared from its hydrate — Amylic Alcohol (C 5 H u HO), or, as it is commercially known, Fousel or Fusel Oil. This is combined AMYL. 151 with various acids and forms oxides or ethers, which are separated by distillation in the same manner as ethyl ethers. (See page 78.) Its compounds, however, are not known com- mercially as ethers, but by the acids with which they are combined, as Acetate of Amyl, etc. Nitrite of Amyl is the only U. S. official compound, but the Br. P. includes Amylic Alcohol also. (See page 95.) The following are the preparations of Amyl generally known and employed in pharmacy and the manufacture of fruit flavors. Amyl Acetate CgHnCoHgO., I Acetate of Amyl. Amyl Butyrate C 5 H 11 C 4 H 7 O g ' Butyrate of Amyl. Amyl Chloride C 5 H n HCl Chloride of Amyl. Amyl Formate C 5 H 11 CHO s Formate of Amvl. Amyl Hydrated Oxide* CgH^HO Fusel Oil, Amyloxide. Amyl Iodide j CgH^I Iodide of Amyl, Iodamyl. Amyl Nitrate CgH-^NOg Nitrate of Amyl. Amyl Nitrite ; CgH^NOg Nitrite of Amyl. Amyl Valerianate j C 5 H 11 C 5 H 9 2 [ Valerianate of Amyl. Of the foregoing, the Acetate of Amyl, by the resemblance of its odor to the jargonelle pear, is often called Pear Oil, and the valerianate, by its resemblance to the odor of apples, is called Apple Oil. The others are variously combined to make fruit flavors. Amylene — C 5 H 10 . — This is an etherial liquid made from Amylic Alcohol by abstracting from it the elements of water. It was formerly used as a substitute for ether, but is now no longer employed in medicine. 176. This Alcohol acid, an iv. h ! j. ,1 until th Amyl Nitris, U. S., Br. Nitrite of Amyl. C 5 H u N0 2 . is a volatile liquid made by adding to purified Amylic in a capacious glass retort an equal volume of nitric -I gradually heating to near the boiling point when the will proceed spontaneously. The distillate is collected e temperature in the retort rises to ioo° C. (212 F.) See Ali ohol Amyli 152 A.MYLUM. and then discontinued. The distillate is agitated with water rendered alkaline with potassa or lime, and the oily layer which separates upon standing is distilled, the portion coming over between 95 and ioo° C. being the Nitrite of Amyl. Other Amyl Ethers are made in a similar manner. Nitrite of Amyl Pearls are made by enclosing a few drops of Nitrite of Amyl in thin glass capsules. These are broken in the handkerchief when desired to be used by inhalation for headache or other disorders. Uses. — Nitrite of Amyl is used medicinally by inhalation for spasmodic diseases, asthma, epilepsy, etc., and for nervous headache. It is sometimes given in doses of ^ to 1 minim, much diluted. 177. AMYLUM. Starch. C 6 H io°5- This substance is more familiar to the grocer than the drug- gist. It exists in plants, and is obtained from various grains, tubers, roots, etc., by separating it in various ways from the other substances with which it is associated. The starch obtained from various substances does not differ in chemical composition, but only in physical appearance. The U. S. P. directs starch obtained from the seed of common wheat ( Triti- cum vulgare) ; the Br. P. mentions wheat, corn or rice starch as official ; but in pharmaceutical practice starch from almost any source is used, as the druggist uses whatever is furnished by the manufacturers. It is prepared by manufacturers by grinding the grain to a fine powder, washing it with an abund- ance of water, allowing the starch to settle, draining off the water and drying. In the industrial arts starch is extensively employed for many purposes. The manufacture of grape sugar or glucose from starch has been developed to an important industry in this country. Dextrin is also a derivative of starch consider- ably used in manufacturing and the arts. In pharmacy starch is employed as a dusting for pills, sup- AMYLUM. 153 positories, etc., an ingredient in toilet powders and for making several preparations. In medicine starch is made into demul- cent food for invalids and is used in the form of dust, decoc- tion or glycerite, externally, to allay inflammation, prevent chaffing, etc. Some of its compounds are used internally to prevent the irritation of caustic medicines. Varieties of Starch. — Wheat, rye, corn, rice hid potato starch are the varieties usually known in the market as starch. Starch obtained from any or all of these substances is known as laundry starch, but "corn starch" is put up in packages especially as an article of diet. Arrozvroot {Maranta) is a starch obtained from the rhizome of Maranta arundinacea. It was formerly official, but has now been deleted. It is used as a nutritious food for invalids. Much of the "arrowroot" that is sold, however, consists only of our common varieties of starch. Sago, a starch prepared from the pith of the sago palm, and Tapioca, prepared from the tubers of the tapioca or cassava plant, are familiar varieties of starch used as food. Rice and Pearl-Barley, as they are sold by grocers, consist mainly of starch. 178. Amylum Iodatum, U. S. Iodised Starch- — Iodide of Starch. Starch, 95 parts, or 418 grains. Iodine, 5 parts, or 22 grains. Distilled Water, a sufficient quantity to make . . . 100 parts, or about 1 oz. av. "Triturate the iodine with a little distilled water, add the starch gradually, and continue triturating until the compound assumes a uniform blue color approaching black. Dry it at a temperature not exceeding 40 C. (104 F.), and rub it to a fine powder." There seems to be some difference of opinion as to whether this is a chemical or mechanical compound. Uses. This is given internally in doses of from two to four drachms, its advantage being that iodine max- be freely admin- istered without danger of gastric or intestinal irritation. 154 ANILINA. Soluble Iodide of Starch. — A soluble Iodide of Starch may be made by dissolving 180 grains of iodine in 5 fl. drachms of ether and triturating the solution with 3 troyounces of starch until the ether has evaporated, then heating by water- bath for half an hour with occasional stirring. The starch is thus converted into dextrin and becomes soluble. It contains when completed about 4 per cent, of iodine, and may be made into solution or syrup, or given in powder like the above. 179. ANILINA. Aniline — A nilinc Oil — Phenylamine. C 6 H 7 N. This alkaloid was first obtained from indigo by dry distilla- tion, and derives its name from Anil, a specie of plants from which indigo is obtained. It was afterward obtained from coal-tar, benzene and other products of coal and petroleum dis- tillation and is now mainly obtained from these sources. It is a colorless, oily, inflammable liquid, the base of the various well-known salts known in the market as aniline dyes. Drug- gists formerly had quite a sale for these aniline salts under various fanciful names, but since the introduction of pro- prietary package dyes they are but little called for, but are somewhat used in pharmacy for making colors and inks. The process for obtaining Aniline is complicated and varies con- siderably with the substance from which it is derived ; there- fore it is not repeated here. Aniline forms salts with most of the acids and negative elements, which give a great variety of beautiful colors known as "Aniline Dyes," the manufacture of which constitutes a great industry. Aniline and its compounds are not used in medicine. The following are a few of the best known Aniline Dyes : 180. Red Aniline or Fuchsine, also known as Magenta, Solferino, ros- aniline, rosdine, rubine and by many other similar names, is made by various processes, which consist in oxidizing aniline oil by means of acids or other oxidizing agents. It is the basis of most of the other aniline dyes. Many modifications of the red color are produced by different combina- tions and processes. ANTIMONIUM — ANTIMONY. 155 181. Blue Aniline is made both soluble and insoluble of various shades of color. The former is known as soluble or alkali blue, Nicholsons blue, diphenylamine blue, etc. ; the latter as Bleu de Lyons, Bleu de Nuit, blueine, Mulhouse blue, Aldehyde blue, triphenyl rosaniline, etc. 182. Violet Aniline, Mauvine, Purple A?iiline, Etc. — A great variety of violets, ranging from bluish to redish, are produced by various combinations. The most familiar are Hoffman's Violets, made by acting on fuchsine with methel or ethyl iodide or bromide. Those having a reddish shade are marked Hoffman's Violet R., while those having a blue shade are known as Hoffman's Violet B. or BB. or BBB., etc. 183. Green Aniline. — A variety of green shades are also made by vari- ously combining yellows and blues, or by acting upon fuchsine with various substances. They are variously known as aldehyd green, iodine green, methyl greeti, etc. 184. Black Aniline, Negrosine, or Gray Aniline. — This is made by acting upon mauvine with strong sulphuric acid and aldehyd, and by other cheaper methods. All tints from light gray to black may be produced with this dye. It is the basis of many of the popular black inks. 185. Yellow Aniline and Orange Aniline are mostly obtained from the products of fuchsine manufacture, chrysaniline, etc. 186. Brown Anilines are made by heating fuchsine and formic acid together, and by other methods. ANTIMONIUM — ANTIMONY. Symbol, Sb. (Stibium); Atomic weight, 120; Sp. gr. 6,715. The metal Antimony occurs in nature to a small extent but is generally found alloyed or associated with other metals or combined with sulphur. The common commercial source being Sulphide of Antimony, Gray Antimony, or stibnite (Sb 2 S 3 .) This ore was called by the alchemists lupus metallo- ruiii, and metallic Antimony was named by them, regulus, or regains of Antimony. Metallic Antimony is a bright, silver-gray metal, very brittle, easily pulverized, and is one of the most important alloy- metals we possess. Its salts are considerably used in phar- macy and medicine. lo6 ANTIMONIUM — ANTIMONY. The following are the principal alloys in which Antimony is employed : 187. Babbitt-Metal. — The best Babbitt anti-friction metal, which is used as boxes for the journals or axles of machinery, is composed of tin, 10 parts ; copper and antimony, each 1 part. A cheaper alloy is made by using a portion of lead in place of tin. 188. Britannia-Metal. — The best Britannia-Metal is composed of tin, 81 parts; antimony, 16 parts; copper, 2 parts; zinc, 1 part. Other grades of Britannia are required to be softer for various purposes, and a smaller propor- tion of Antimony is used. Lead is also used in cheaper grades in place of a portion of the tin. 189. Pewter. — The best plate pewter is made with tin, 85 parts ; Antimony. 8 parts ; copper, 5 parts ; bismuth, 2 parts. Cheap Pewter is made of tin and lead only. 190. Type-Metal. — This is made of lead, 80 to 83 parts, and Antimony, 17 to 20 parts. Other metals are often added, and varying proportions of lead and Antimony used. Lead 75 parts, Antimony 20 parts, tin 5 parts; or, lead 70 parts, Anti- mony 25 parts, tin 5 parts, are good proportions. Many type-founders use a small proportion of copper in the alloy. 191. Stereotype-Metal is made of lead, 112 parts; Antimony, 18 parts; tin, 3 parts. Of the many salts and preparations of Antimony that were formerly used in medicine but few are now employed. The following are the official salts : 192. Antimonii et Potassii Tartras. Tartrate of A ntimony and Potassium — Tartar Emetic, U. S. — Tartrated A ntimony, Br. 2KSbOC 4 H 4 6 .H 3 0. This double salt is the most important medicinal prepara- tion of Antimony. It may be made by the old official process, which is as follows : Oxide of Antimony, in very fine powder, 2 ounces. Bitartrate of Potassium, in very fine powder, 2j^ ounces. Distilled Water, 18 ounces. To the water, heated to boiling in a glass (or porcelain) vessel, add the powders previously mixed and boil for an hour. ANTIMONIUM — ANTIMONY. 157 Then filter the liquid while hot and set aside that crystals may form. Lastly, dry the crystals and keep them in a well- stopped bottle. The British process is similar, except that the powders are first mixed together, moistened with water to a pasty mass and allowed to stand twenty-four hours before boiling with the remainder of the water, the boiling being continued only 15 minutes. This salt is found in the market generally in the form of a white powder, familiarly known as Tartar Emetic. It is soluble in about 17 parts of cold or 3 parts of boiling water. Uses. — Tartar Emetic is given in doses of from y 2 to 1 grain, repeated if necessary, as an Emetic. In doses of -^ to y grain it is used as a diaphoretic and alterative. It is much prescribed and used as an ingredient in cough medicines, and is also employed for making irritating ointments and plasters. As an antidote for poisoning by overdose of this salt, some solution containing tannin should be given freely. Strong tea will do. Tannin forms with it an insoluble salt. 193. Antimonii Oxidum. Oxide of Antimony. This is trioxide of Antimony or Antimonious Oxide. It is made by treating Sulphide of Antimony with hydrochloric acid, by the aid of heat, then adding nitric acid and water, and filtering, which makes a solution of Chloride of Antimony. The filtrate is then poured into a large quantity of water, which precipitates Oxychloride of Antimony. To convert this into the oxide it is treated with water of ammonia for two hours, and then washed with distilled water to remove chloride of ammonium. The British Pharmacopoeia directs it to be made by precipi- tating 16 fl. ounces of solution Chloride of Antimony by pouring it into 2 gallons (Imperial) of water, washing the precipitate with distilled water, then adding a solution of 6 ounces of carbonate <>f sodium in 2 pints (Imperial) of water. 1 58 ANTIMONIUM — ANTIAK (NY. leaving them in contact half an hour with frequent stirring, collecting the precipitate and washing with boiling distilled water. Uses. — The Oxide of Antimony is used chiefly for making other antimonial preparations. The only form in which it is administered unchanged is in antimonial powder. 194. Antimonii Sulphidum. Sulpiride or Sutyhuret of Antimony. Native Sulphide of Antimony, purified by fusion and as nearly free from arsenic as possible — U. S. This is the commercial or crude Sulphuret of Antimony from which the other antimonial preparations are derived. It is considerably used as an ingredient of condition powders. 195. Antimonii Sulphidum Purificatum. Purified Sulphide of Antimony — Black Antimony. This is the same as the foregoing, except that it is purified by dissolving out whatever arsenious sulphide is present with ammonia. Sulphide of Antimony, 16 ounces av. Water of Ammonia, 8}4 fl. ounces. Water, a sufficient quantity. Reduce the Sulphide to a very fine powder; add the water of ammonia, macerate for five days with frequent agitation ; then pour off the water of ammonia. Wash the residue thoroughly with several portions of water, and, finally, dry by heat. Uses. — Whenever sulphide of antimony is directed to be used in medicine, the preparation thus purified should be employed. It is considerably used in making horse and cattle powders. ANTIMONIUM — ANTIMONY. 159 196. Antimonium Sulphuratum. SulpJinrated Antimony. Purified Sulphate of Antimony, . . 2 ounces av. Solution of Soda, 22^ fl. ounces. Distilled Water. Diluted Sulphuric Acid, each a sufficient quantity. Mix the Antimony with the solution of Soda and 4 pints of distilled water, and boil the mixture over a gentle fire for two hours, constantly stirring and adding a little distilled water occasionally to maintain the same volume. Strain the liquid then through a double muslin strainer and drop into it while yet hot diluted sulphuric acid so long as it produces a precipi- tate. Wash the precipitate with hot distilled water until all traces of sulphuric acid are removed, then dry, and reduce to a fine powder. The powder is composed of sulphide and Oxide of Antimony. Uses. — This is given as an alterative and diaphoretic in small • doses and an emetic in doses of from 2 to 5 grains. It is an ingredient of the well-known Plummer's Pills, which are official. Other Salts of Antimony. The foregoing are all the Salts of Antimony that are used to any extent, in pharmacy, but the following unofficial salts are sometimes employed, and are therefore mentioned : 197. Bromide of Antimony — SbBr 3 . — Made by adding dry Antimony to bromine in a retort, agitating until the reaction is complete, then purifying by distillation and collecting the crystals. 198. Fluoride of Antimony — SbFl 3 . — By distilling Antimony and fluo- ride of mercury together and collecting the white mass. 199. Iodide of Antimony - Sbl 3 . — By combining Antimony and iodine and allowing them to remain in combination until the reaction is completed. 200. Oxides of Antimony.— Besides the official oxide (trioxide) of Anti- mony, it forms a tetroxide, Sb 8 4 , known as antimonious acid, and ■& pent- ox id c Sb 8 B known as antimonic anhydride. 201. Oxychloride of Antimony — SbOCl — Powder of Algaroth. — By pouring solution of Chloride of Antimony into a considerable quantity of water, this salt is precipitated. 160 ANTIPYRIN. 202. Oxysulphide of Antimony — Kermes Mineral, Golden Sulphide of Antimony. — By boiling one troyounce of Sulphide of Antimony for one hour with 1 6 pints of water and 23 troyounces carbonate of sodium, then allowing to stand twenty-four hours, collecting the precipitate, washing and drying. It is a mixture of sulphide and oxide of Antimony; was formerly official but is now seldom used. Uses same as Sulphurated Antimony. 203. Pentasulphide of Antimony — Sb 3 S 5 .— By passing hydrosulphuric acid gas through antimonic anhydride suspended in water until the reaction is complete. This is similar in composition to the following: 204. Sulphantimoniate of Antimony — Schlippes Salt. — By dissolving 70 parts of carbonate of sodium in 250 parts of water, boiling and mixing with 26 parts of lime mixed with 80 parts of water ; then adding 36 parts of levigated Sulphide of Antimony and 7 parts of sublimed sulphur, boiling until the gray color disappears, filtering and crystallizing. 205. Sulphate of Antimony — Sb 2 (S0 4 ) 3 . — By boiling Antimony with strong sulphuric acid, and collecting the white mass. 206. Vitrified Antimony — Glass of Antimony. — By roasting Sulphide of Antimony first in a shallow vessel, and then melting it in a crucible, and pouring it upon an iron plate. Besides the foregoing, some other preparations and compounds of Antimony are occasionally wanted Btttter of Antimony is the Solution of Terchloride of Antimony (which see). Crocus of Antimony is made by fusing equal parts of Black Antimony and saltpetre together; Liver of Antimony by fusing 7 parts of Black Antimony with 2 parts of dry carbonate of sodium ; Ethiops of Antimony by triturating 1 part of mercury with 2 parts of Black Antimony until the mercury is extinguished. 207. ANTIPYRIN. C 30 H 18 N 4 O 2 . This is made by Meister, Lucius & Briining, of Hochst on the Rhine, after a patented process, by heating methyl-oxy- chinizin with an excess of phenyl-hydrazin to boiling, and collecting the white crystalline powder which forms. A similar preparation called Dr. Knorr s Antipyrine is now made in this country. It is used to reduce the temperature, and as. a general sedative in febrile conditions. The dose is from 15 to 40 grains. Antifebrin is a similar proprietary compound similarly indi- cated and used in febrile conditions. AQ LLE — WATERS. 161 AQU^ — WATERS. As applied to pharmacy in this country and Great Britain the term Agues or Waters includes only aqueous solutions of aromatic or volatile substances, either with or without the aid of some insoluble medium by which their solution may be facilitated. These waters are more commonly called " medicated waters," but with one or two exceptions they are hardly entitled to that appellation. They are used in pharmacy for making a few medicinal preparations, and in medicine are prescribed as vehicles or aromatic dilutents for more active remedies. The United States Pharmacopoeia includes in the waters, aqua ammonise and aqua chlori, which are solutions of gas in water; the British Pharmacopoeia includes these among the solutions, which is, no doubt, the more proper classification. In German pharmacy several preparations are classed among the waters that more properly belong with the solutions ; and in French Pharmacy, a large number of preparations are in- cluded in the " Eaux " which should be in entirely different departments. Under this heading, therefore, only those solu- tions of volatile substances which are naturally classed with the waters as understood in this country and Great Britain will be mentioned. The processes by which they are made are as follows : 208. By Solution. a. Of those made with cold water, the solutions of gaseous ammonia and chlorine ; of chloroform, carbolic acid and crea- SOte ; of bitter almond oil, and tar may be mentioned. With the exception of the gaseous solutions, which require special apparatus, the remaining waters are made simply by agitating tin- substances occasionally for several days with cold water. b. Hot water dissolves the volatile oils much more readily than cold, and very good waters ma)- be made by thoroughly agitating the volatile oil directed in hot water, allowing to 162 AQl'.V. — WATERS. stand for several hours, and filtering. Nearly all the waters in which volatile oils are used can be satisfactorily made in this manner. 209. By Distillation. a. From fresh or dried aromatic fruit, flowers, leaves, bark, or other parts of plants. The substance is introduced with water into a still, and one half or less of the water (which is charged with the volatile constituents of the substances) is distilled over. Or steam is passed through the substances contained in a still, the vapor condensed, and the liquid separated from oily particles by Alteration. Most of the waters of the British Pharmacopoeia are made in this manner. b. From essential oils of plants, by mixing them with a quantity of sand or some other substance to separate the oily particles, then adding water and distilling over about half the quantity used. The proportion is generally one fl. drachm of essential oil, 4 ounces of sand, and one gallon of water. Distill 4 to 6 pints. This is a very good way to make Distilled Waters. They generally keep better than when made from the fruit, flowers, leaves, etc. Distillation, whenever it is admissible, is to be recommended above all other processes for the preparation of Waters. The process and apparatus are further described on page 26. When made by distillation, the distilled waters while still warm should be put in small bottles, sealed, and put in a cool place. They will then keep for years. 210. By Filtration or Percolation. a. The process formerly official for making most of the Waters of the United States Pharmacopoeia, was to rub 30 minims of the essential oil with 60 grains of carbonate of magnesium, then with 2 pints of water, and filter. This was generally a very satisfactory process, but it was thought desirable to change the process in the 1880 revision by substi- AQU/E — WATERS. 163 tuting cotton as a means of mechanically dividing the oil to aid in its solution. The former process is, however, very generally used in preference to tke latter. Other substances besides carbonate of magnesium, as phosphate of calcium, powdered pumice-stone, kaolin, precipitated chalk, etc., are sometimes used, but they have no advantages over it. b. The 1880 United States Pharmacopoeia directs many of the Waters to be made by adding the essential oil gradually to cotton, picking it thoroughly to pieces to distribute the oil evenly, then packing the cotton in a conical funnel, and percolating with water until the desired quantity is obtained. The cotton (which is preferably absorbent cotton) is best impregnated with the essential oil by the use of cards such as are employed Tor carding wool. Thirty minims of the oil with 60 grains of cotton is the proper quantity to make two pints of water. The following are the Waters generally used and prescribed in this country. For Water of Ammonia, see Ammonia. For Chlorine Water, see Chlorine. 211. Aqua Amygdalae Amarae. Bitter Almond Water. Oil of Bitter Almonds 15 minims. Distilled Water, 2 pints. Dissolve the oil in the water by agitation (208 a), and filter through a well-wetted filter. This is an agreeably flavored vehicle. The German Pharmacopoeia directs this water to be made from Bitter Almonds 12 parts by first bruising and pressing out as much as possible of the fixed oil, then powdering and mixing with 80 parts of water, and 1 part of alcohol, and allowing to stand 12 hours. Eleven parts are then to be care- fully distilled off into a well cooled receiver, containing one part of alcohol. This is then to be assayed to determine the amount of hydrocyanic acid, and the distillate so diluted with a mixture of 1 part of alcohol mixed with 5 parts of water, that 1 part of hydrocyanic arid will be contained in 1,000 parts of the finished liquid. (U AOU.K — WATERS. 212. Aqua Anethi, Br. Dill Water. Dill Fruit, bruised, I pound av. Water, 20 pounds av. Distill 10 pounds, (209 a.) This very much resembles Anise Water. It is seldom used in this country, but is much prescribed in Great Britain. 213. Aqua Anisi, U. S. Anise Water. Oil of Anise, 30 minims. Carbonate of Magnesium or Cotton, . 60 grains. Distilled Water, 2 pints. Make by rubbing the oil with the magnesium or picking with the cotton, adding the water and filtering or percolating as directed (210 a or b.) It may also be made by mixing 1 fl. drachm of oil with 4 ounces of sand and 8 pints of water, and distilling 4 pints (209 b.) The British Pharmacopoeia directs : Anise Fruit, bruised, 1 pound av. Water, 20 pounds av. Distill 10 pounds, as directed (209 a.) Anise Water is used as a vehicle for medicines, especially for children. 214. Aqua Aurantii Florum. Orange Flower Water. The United States Pharmacopoeia directs 40 parts of recent Orange Flowers and 200 parts of water to be mixed, and 100 parts to be distilled. Orange Flower Water is seldom, if ever, made in this coun- try. As imported, it is known as Triple Orange Flower Water. By diluting with two parts of distilled water, ordinary Orange Flower Water is made. An inferior Orange Flower Water may be made by rubbing 20 minims of Oil of Orange Flowers (Oil of Neroli) with 60 AQU/E — WATERS. 165 grains carbonate of magnesium, adding 2 pints of water, and filtering. A better preparation may be made by mixing 30 minims of Oil of Orange Flowers (Neroli) with 4 ounces of sand and 6 pints of water, and distilling 3 pints. Neither of these, however, represent the true flavor of the water distilled from the flowers. Orange Flower Water is used in a few medicinal prepara- tions and elixirs, but chiefly in toilet preparations, etc. 215. Aqua Camphorae. Camphor Water (U. S., 1880). Camphor, 120 grains. Alcohol, y 2 fl. ounce. Cotton, y 2 ounce. Distilled Water, 2 pints. Dissolve the Camphor in the alcohol ; moisten the cotton with the solution ; allow the alcohol to evaporate ; pack in a percolator, and add water until 2 pints have passed. The 1870 United States Pharmacopoeia directed 120 grains of Camphor to be rubbed with 40 minims of alcohol, then with 240 grains of carbonate of magnesium, and then percolated with water until 2 pints were obtained. The British Pharmacopoeia directs y 2 ounce av. of Camphor to be crushed and enclosed in a muslin bag and kept at the bottom of a bottle containing 10 pounds of distilled water (by means of a glass rod ) for at least two days before using, and then pour off the solution as required for use. Camphor Water is used as a mild antispasmodic, in doses of 1 .. to 1 fl. ounce, and as an addition to many medicines. 216. Aqua Carbolisata, P. G. Carbolic Acid Water. Liquefied Carbolic Acid (29) 33 parts. Water 967 parts. Mix them. This was formerly official in the United States Pharmaco- poeia but has been deleted. 166 AQ U Al — W AT E RS . 217. Aqua Carui, Br. Caraway Water. Caraway Fruit, bruised, 1 pound av. Water, 20 pounds av. Distill 10 pounds as directed, (209 a.) It may also be made by mixing 1 fl. drachm of Oil of Cara- way Seed with 4 ounces of sand and 8 pints of water, and distilling 4 pints. This is official only in the British Pharmacopoeia. It is a pleasantly flavored water like Anise or Dill. 218. Aqua Chloroformi, Br. Chloroform 1 1 T ater. Chloroform, 1 fl. drachm. Distilled Water, 25 fl. ounces. Put them in a quart bottle closely stopped and shake them together until the Chloroform is entirely dissolved. This Solution of Chloroform is used as a mild sedative in doses of y 2 to 2 fl. ounces. 219. Aqua Cinnamomi. Cinnamon Water (U. S., 1880). Oil of Cinnamon, 30 minims. Cotton, 60 grains. Distilled Water, 2 pints. Add the oil to the cotton ; pick, pack, and percolate with the water, (210 b.) The 1870 United States Pharmacopoeia directed 30 minims of Cinnamon Oil to be rubbed with 60 grains carbonate of magnesium, and then with 2 pints of distilled water, and filtered. The 1880 preparation is to be preferred. The British Pharmacopoeia directs 20 ounces av. of Cinna- mon Bark, bruised, to be mixed with 20 pounds of water, and 1 gallon to be distilled, (209 a.) It may also be made by mix- ing 1 fl. drachm of Cinnamon Oil with 4 ounces of sand and AQUJE — WATERS. 167 8 pints of water, and distilling 4 pints. This makes a superior Cinnamon Water. Cinnamon Water is used in making several preparations and is much prescribed as an adjuvant or dilutent for other medi- cines. It may be given as a mild stimulant in doses of 1 fl. ounce. 220. Aqua Creasoti, U. S. Creasotc Water. Creasote, 73 grains. Distilled Water, 1 pint. Mix, agitate, and filter through a well-wetted filter. This is very similar to carbolic acid water. 221. Aqua Destillata. Distilled Water. Water, 1,000 parts or 15 pints. Distill the water from a suitable apparatus, throwing away the first pint and collecting the next 12 pints that are distilled over. Preserve in full, well-stopped bottles. 222. Aqua Fceniculi. Fennel Water. Oil of Fennel, 15 minims. Carbonate of Magnesium or Cotton, . . 60 grains. Distilled Water, 2 pints. Rub the oil with the magnesium, or pick with the cotton ; add water, and filter or percolate as directed, (210 a or b.) The British and German Pharmacopoeias direct this to be made by distillation, as follows: Fennel Fruit, bruised, 1 pound av. Water, 20 pounds av. Distill 10 pounds. It may also be made by mixing 1 fi. drachm of Oil of Fennel with 4 ounces of sand and 8 pints of water, and distilling 4 pints. Fennel Water is used as a pleasant vehicle and dilutent, the same as .Anise. 168 AQUiE — WATERS. 223. Aqua Gaultheriae. 1 J r intergreen 1 Vater. Although this water is not known to be official in any Phar- macopoeia, yet it is used and prescribed by physicians quite generally. It may be made as follows : Oil of Wintergreen 30 minims. Phosphate of Lime, precipitated, . . .120 grains. Distilled Water 2 pints. Rub the oil with the phosphate of lime, add the water and filter. It may be made by distillation as follows : Wintergreen, fresh herb, 20 ounces av. Water, 2 gallons. Distill 8 pints. Or by mixing 1 fl. drachm Oil of Wintergreen with 4 ounces of sand and 1 gallon of water, and distilling 4 pints. 224. Aqua Lauro Cerasi, Br. Cherry Laurel Water. Fresh Leaves of Cherry Laurel, . . . 1 pound av. Water, 3^ pints. Crush the leaves and macerate with water in a warm place for 24 hours, then distill 20 ounces. The Cherry Laurel is seldom found in this country, and it has been demonstrated, by the late Prof. Proctor, that the leaves of our ordinary wild cherry treated in the same way will produce an identical preparation. It is, therefore, advised to use them in making ''Cherry Laurel Water" in this country. Cherry Laurel Water may also be made by adding 15 drops Oil of Cherry Laurel to 2 pints of distilled water, and agitat- ing until dissolved. It is very similar to bitter almond water, which may be used for it. AQU^E — WATERS. 225. Aqua Menthas Piperitae. Peppermint Water. Oil of Peppermint, 30 minims. Carbonate of Magnesium or Cotton, . 60 grains. Distilled Water, 2 pints. Rub the oil with the magnesium or pick with the cotton ; add water, and filter or percolate as directed, (210 a or b.) The British Pharmacopoeia directs this to be made by mix- ing \y 2 fl. drachms of Oil of Peppermint with 15 pounds of water, and distilling 10 pounds. The oil should be mixed with 4 ounces of sand as directed, (209 b.) The German Pharmacopoeia directs it to be made by mixing 1 part of cut Peppermint (herb) with water, and distilling 10 parts. Peppermint Water is very much used and prescribed in medicine as a vehicle for other medicines, especially in flatu- lence and other dyspeptic troubles. 226. Aqua Mentha Viridis. Spearmint Water. Oil of Spearmint, 30 minims. Carbonate of Magnesium or Cotton, . . 60 grains. Distilled Water, 2 pints. Make in the same manner as is directed for peppermint water, (225.) Its uses are similar. 227. Aqua Picis, P. G. Tar Water. Tar I part. Pumice-stone, in fine powder 3 parts. The pumice-stone should be washed and dried and mixed with the tar. Then to make Tar Water: Take of the above mixture, 4 parts. Water 10 parts. 170 AOU.E — WATERS. Shake together for 5 minutes, and filter. It should be freshly made when desired for use. Tar Water was official in the 1870 U. S. P. under the title Infusum Picis Liquidce. Tar Water, as a domestic remedy, is a well-known prepara- tion. It is made by putting a pint of Tar in a gallon or more of water and stirring occasionally. 228. Aqua Pimentae, Br. Pimento Water. Pimento, bruised, 14 ounces av. Water, 20 pounds av. Distill 10 pounds. This may also be prepared by adding 30 minims Oil of Pimento to 60 grains of cotton ; picking, packing and percola- ting with 2 pints of distilled water. It is not as good prepared with Carb. Magnesium, as the oil has an acid reaction. 229. Aqua Rosae. Rose Water. Recent Pale Rose (petals), 2 parts. Water, 10 parts. Distill by means of steam, 5 parts. The same proportions may be used, and the distillation per- formed by the ordinary still. The British Pharmacopceia directs 10 pounds of fresh hundred-leaved rose petals to be mixed with 50 pounds of water, and 10 pounds distilled. The German Pharmacopoeia directs 4 drops of Oil of Rose to be shaken with 1,000 grammes (about 2 pints) of tepid water for some time, and then filtered. Rose Water, to be fine, should be redistilled. It cannot be profitably distilled in this country, as our roses lack the fragrance of the European varieties. Triple Rose Water may be bought of the importing drug- gists, and reduced with one or two parts of distilled water. It is then much better and cheaper than any of domestic produc- tion. AQU.E — WATERS. 171 A fair quality of Rose Water may be made by adding 10 drops of Otto (Oil) of Rose to 30 grains of cotton, picking, packing and percolating with 2 pints of hot distilled water. It may also be made by mixing 20 minims of Otto of Rose with 4 ounces of sand and one gallon of water, and distilling 4 pints. The imported Rose Water is, however, superior to any home production. Rose Water is used in several official preparations, and is much prescribed as a solvent for various substances used as lotions, etc. ; it is also a favorite article for the toilet, either alone or mixed with other substances. 230. Aqua Sambuci, Br. Elder Floiver Water. Fresh Elder Flowers, 10 pounds av. Water, 50 pounds. Distill 10 pounds. This is used as a pleasant flavored water for medicinal lotions, etc. Other Medicinal Waters. Besides the foregoing waters, which are mostly official in either the United States, British, or German Pharmacopoeias, others are frequently required, but they are all made in the same general manner as those herein given. Of those made from fruit or seeds, angelica, coriander, juniper, parsley, etc., may be made in the same manner as dill or fennel water; of those made from flowers or herbs, balm, borage, chamomile, hyssop, lavender, lettuce, lily, melilot, myrtle, origanum, peach, pennyroyal, rosemary, sage, thyme, violet, wormwood, etc., may be made in the same manner as cherry laurel or elder flower water; of those made from barks, and oilier substances, lemon, orange, lime, sassafras, valerian, vanilla, and others, may be made by distillation in the same manner as is directed for making cinnamon water. 172 ARGENTUM — SILVER. ARGENTUM — SILVER. Symbol, Ag. Atomic weight 108. Sp. gr. (fused) 10.4. Silver is a well-known elementary metal extensively used in the arts and employed as the money currency of many coun- tries. It is obtained mostly from its ores, from which it is separated by various means, but is sometimes found in small quantities, as metallic silver. Its uses in the arts and com- merce of the world are too well-known and general to require mention. In pharmacy it is used in the metallic state only in the form of silver leaf (Argent 'it in Foliatum) for coating pills, cachous, etc.; but its salts — particularly the nitrate of silver — are much employed for making various preparations, and are somewhat used in medicine. Solutions of its salts are precipitated by chlorine compounds forming a curdy white precipitate, insoluble in nitric acid but soluble in water of ammonia. This forms a very delicate and characteristic test for silver. The following are the U. S. official preparations of silver: 231. Argentum Purificatum. Refined Silver. The British Pharmacopoeia, 1885, under this heading describes pure metallic Silver. It may be made by dissolving Coin Silver in nitric acid and water, adding hydrochloric acid, which precipitates chloride of silver, leaving the copper alloy in solution ; the liquid is poured off, the precipitate washed and melted, with carbonate of sodium, in a crucible. The melted metal is then poured off and consists of pure silver. 232. Argenti Cyanidum. Cyanide of Silver. AgCN. Tin's salt is made by generating hydrocyanic gas in a retort by adding sulphuric acid to a solution of ferrocyanide of potassium, distilling and conducting the vapor into a glass ARGENTUM — SILVER. 173 receiver containing a solution of Nitrate of Silver, from which Cyanide of Silver is precipitated. It is used in pharmacy for the extemporaneous preparation of diluted hydrocyanic acid, which see, page 61. 233. Argenti Iodidum. Iodide of Silver. Agl. This may be made by precipitating a solution of Nitrate of Silver with a solution of iodide of potassium. It is sometimes given in doses of ^ to 2 grains for syphilis. 234. Argenti Nitras. Nitrate of Silver. AgN0 3 . Nitrate of Silver is the working base of all the silver salts, and is the only silver salt that is employed to any extent in pharmacy or medicine. It is also extensively employed in photography. A process for making it was formerly official but has been omitted in the 1880 United States Pharmacopoeia. The British Pharmacopoeia, 1885, directs it to be made as follows : Refined Silver (231), 3 ounces av. Nitric Acid, 2^ fl. ounces. Distilled Water 5 ounces av. Add the nitric acid and the water to the Silver in a flask, and apply a gentle heat till the metal is dissolved. Decant the clear liquid from any black powder which may be present, into a porcelain dish, evaporate and set aside to crystallize; pour off the liquor and again evaporate and crystallize. The crystals may be drained in a glass funnel. Uses. — Crystallized Nitrate of Silver is used for making all the other Salts of Silver, and is largely employed in photo- graph}-, silver-plating and other arts and industries. In pharmacy it is used for making hair dye, indelible ink, test 174 ARGENTUM — SILVER. solutions, etc., and in medicine is used in solution to remove morbid growths, and as a caustic and escharotic, and internally in gastritis, diarrhcea, and other derangements of the digestive tract, in doses of ^ to ^ grain usually in the form of pills. 235. Argenti Nitras Dilutus. Diluted Nitrate of Silver, U. S. — Nitrate of Silver and Potassium, Br., G. P. The United States Pharmacopoeia directs Nitrate of Silver, 1 ounce. Nitrate of Potassium, 1 ounce. To be fused together in a porcelain capsule at as low a temperature as possible, thoroughly mixed and cast into suitable moulds. The British and German Pharmacopoeias direct Nitrate of Silver, 1 ounce. Nitrate of Potassium, 2 ounces. To be fused together in the same manner ; therefore, the United States preparation is one-half and the British and German preparations one-third Nitrate of Silver. This was formerly called Argenti Nitras Mitigatus or Mitigated Nitrate of Silver. It is cast in the form of cylindrical sticks and also in the form of small cones. Uses. — This is now much used as a caustic and escharotic for external and internal application, as it is milder and just as efficient as the pure lunar caustic. 236. Argenti Nitras Fusus. Moulded Nitrate of Silver. — Fused Nitrate of Silver. — 'Lapis Inf emails. — Lunar Caustic. This is simply crystallized Nitrate of Silver, fused and cast into sticks or points for convenient use. The United States Pharmacopoeia directs it to be made as follows : Nitrate of Silver, 1 ounce av. Hydrochloric Acid, 16 minims. ARGENTUM — SILVER. 175 Melt the Nitrate of Silver in a porcelain capsule at as low a heat as possible, and add to it gradually the hydrochloric acid, stir well, and when nitrous vapors cease to be evolved pour into suitable moulds. The object of adding the hydro- chloric acid is to toughen the moulded sticks, as the fused nitrate alone is very brittle. The British Pharmacopoeia suggests, " To form Toughened Nitrate of Silver ox Toughened Caustic add 5 parts of nitrate of Potassium to 95 parts of the Nitrate of Silver before fusion." Uses. — This is used as an escharotic, but is not so much employed as formerly, the diluted Nitrate of Silver being used instead. It is a favorite popular application for warts and other excrescences. 237. Argenti Oxidum, Oxide of Silver. Ag 2 0. The present United States Pharmacopoeia does not give a process for making this salt. The 1885 British Pharmacopoeia directs as follows: Nitrate of Silver, in crystals, ... ]/ 2 ounce av. Solution of Lime (Lime Water), . 6y fl. ounces. Distilled Water, . 10 fl. ounces. Dissolve the Nitrate of Silver in 4 ounces of the distilled water, and having poured the solution into a bottle containing the solution of lime, shake the mixture well and set it aside to allow the deposit to settle. Draw off the liquid, collect the precipitate on a filter, wash with the remainder of the distilled water, and dry at a moderate temperature. Uses. — The Oxide of Silver is somewhat used as a substi- tute for Nitrate of Silver, being much less caustic, and, there- fore, better suited for internal administration. It may be made into pills Or mixed with other powders and given in capsules. Care must be taken in dispensing this salt not to 176 ARGENTUM — SILVER. triturate it with readily oxidizable substances nor ammonia, as it forms explosive compounds. The photographic art and the use of indelible ink and hair dyes depend upon the conversion of the Nitrate of Silver into Oxide of Silver, which is insoluble. Other Salts of Silver. The foregoing official Salts of Silver are all that are used to any extent in pharmacy or medicine. The following are, however, sometimes required : 238. Acetate of Silver — AgC,H 3 2 . — Made by decomposing a solu- tion of Nitrate of Silver by adding it to a solution of acetate of sodium, col- lecting the precipitate, washing and drying. 239. Bromide of Silver — AgBr. — By decomposing a solution of Nitrate of Silver, by adding it to a solution of bromide of potassium, collecting the precipitate, washing and drying. 240. Chloride of Silver — AgCl. — By adding to a solution of Nitrate of Silver hydrochloric acid or common salt as long as a precipitate is formed, then collecting, washing and drying the precipitate. This is freely obtained by precipitating the washings of photograph plates with common salt. 241. Chromate of Silver — Ag 2 Cr0 4 . — By adding a neutral solution of chromate of potassium to a solution of Nitrate of Silver, collecting, washing and drying the precipitate. 242. Oxalate of Silver — AgX._,0 4 .— By adding a solution of oxalic acid to a solution of Nitrate of Silver, collecting, washing, and drying the precipitate. 243. Phosphate of Silver — Ag ;j P0 4 . — By decomposing a solution of Nitrate of Silver by adding to it a solution of phosphate of sodium, collecting the precipitate, washing, and drying. 244. Sulphate of Silver— Ag,S0 4 — By decomposing a solution of Nitrate of Silver by adding to it a solution of sulphate of sodium, collecting the precipitate, washing and drying. Many other Salts of Silver exist in nature in the form of ores, as Sulphide of Silver, Carbonate of Silver, etc., or may be made in the laboratory by combining it with various acids, but those already mentioned are all that are of interest to pharmacy. ARSENICUM — ARSENIC. 177 ARSENICUM — ARSENIC. Symbol, As: Atomic weight, 75 ; Sp. gr. 5.73 to 5.88. Arsenicum, more commonly called Arsenic, is a brittle, gray- colored metallic element very much resembling antimony in its general appearance and characteristics. It is found in nature as a free metal, but much more abundantly in ores, or combined with other metals as an alloy, or in the form of salts, its sulphides being most common. With oxygen it forms Arsenious Oxide As 2 0, and Arsenic Oxide As 2 O s . With sulphur it forms a disulphide known as realgar ox ruby sulphur, As 2 S 2 ; a trisulphide known as orpiment or yellow sulphide, As 2 S 3 ; and a pentasulphide, As 2 S g . With hydrogen and oxygen it forms true Arsenious Acid, H 3 As0 3 , and Arsenic Acid, H 3 As0 4 ; the former combines with some bases to form salts known as Arsenites, and the latter forms Arseniates. The oxides and sulphides of Arsenic are considerably used in the arts, and somewhat, though not so much as formerly, employed in pharmacy and medicine. The following Arsenical compounds are official in the United States : 245. Acidum Arseniosum. Arsenic — Arsenious Acid or Oxide — White Arsenic — Arsenious A nhydride — Ratsbane. This is the common Arsenic of commerce. It is prepared by roasting Arsenical ores in suitable furnaces, collecting the vapor and resubliming. As will be noticed by-its formula it is not a true acid, but an anhydride or oxide. Uses. In pharmacy, Arsenic Is extensively put up and sold as a rat poison, and its solution with alkalies is used to saturate paper sold as fly-paper; it is also used for making most of the medicinal preparations of Arsenic. In medicine it is employed as an alterative in doses of .}., to J„ grain, and used with 178 ARSENICUM— ARSENIC. other substances as a caustic application to cancers and fungus growths. Antidote.— The most effectual antidote to arsenical poison- ing is freshly prepared ferric hydrate, with which it forms insoluble ferrous arseniate. 246. Arsenii Iodidum. Iodide of Arsenic, U. S.— Iodide of Arsenicum, Br. Asl 3 . This compound is made by directly combining 1 part of Metallic Arsenic in fine powder with 5 parts of Iodine, then warming the mixture in a flask until liquefied, and pouring upon a marble slab to cool. Uses.— Iodide of Arsenic is chiefly used in pharmacy for preparing Donovan's solution ; in medicine it is given as an alterative in doses of -+■ grain, and sometimes used in ointments. 247. Sodii Arsenias. Arseniate of Sodium. Na 2 HAs0 4 7H 2 0. The following process for making this salt was formerly official : Arsenious Acid, in fine powder, .... 960 grains. Sodium Nitrate, in fine powder, .... 816 grains. Sodium Carbonate, dried, and in fine powder, 528 grains. Distilled Water, boiling hot, 8 flounces. Having mixed the powders thoroughly put the mixture into a large clay crucible and cover it with the lid. Expose it to a full red heat until effervescense has ceased and complete fusion has taken place. Pour the fused salt on a porcelain si;!!, and .1. soon as it has solidified, and while still warm, put it into the boiling water and stir until it is dissolved. Filter Ihc solution and set it aside to crystallize, etc. Uses.— The properties of this salt are the same as arsenious acid; the dose is from -, 1 ., to \ of a grain. AURUM — GOLD. 179 Other Salts of Arsenic. The foregoing are the Salts of Arsenic mainly used in pharmacy and medicine, but the following are sometimes employed : 248. Bisulphide of Arsenic or Realgar — As 3 S 2 . — Made by fusing together 5 parts of Arsenious Acid and 3 parts of sulphur. 249. Bromide of Arsenic — AsBr 3 . — By dusting Arsenic in powder in a retort filled with bromine vapor, and distilling. 250. Chloride of Arsenic — As Cl 3 . — By acting upon metallic Arsenic with chlorine gas. 251. Trisulphide of Arsenic or Orpiment. — As 2 S 3 — By fusing 5 parts of Arsenious Acid with 5 parts of sulphur. AURUM — GOLD. Symbol, Au ; Atomic weight, 196; Sp. gr. average 19.3. Gold is the most valuable of the metallic elements. It is used as the standard money bases of all countries, and on account of its value, malleability, ductility, and permanence of color is extensively used for ornamentation and for making useful and valuable articles. It is obtained mainly as a free metal or alloyed with other metals. Metallic Gold is used in pharmacy only in the form of gold leaf, for coating pills, cachous, etc. The only Salt of Gold which is used to any extent in pharmacy or medicine is the Chloride of Gold and sodium, which is official in the United States and German Pharmacopoeias. 252. Auri et Sodii Chloridum. Chloride of Gold and Sodium. A mixture composed of equal parts of dry Chloride of Gold (AuCl 2 ) and chloride of sodium 1 NaCl.). — U. S. The German Pharmacopoeia directs 65 parts of pure Gold to be dissolved by gentle heat in a mixture of 65 parts of nitric acid and 240 parts of hydrochloric acid; the solution is then 180 BALSAMA — BALSAMS. em to be diluted with 200 parts of water and 100 parts of pure dry chloride of sodium dissolved in the mixture, which is then to be evaporated to dryness by means of a water-bath, with constant stirring. Uses.— This salt is considerably used in photography for "toning" prints, and for electroplating. In medicine it is given as an alterative in doses of fa to % grain. Other Salts of Gold. The following Salts of Gold are sometimes directed or ployed in pharmacy and medicine. 253. Bromide of Gold— AuBr 3 .— Made by dissolving gold in a mixture of nitric and hydrobromic acids, concentrating and crystallizing. 254. Chloride of Gold— AuCl 3 .— By dissolving Gold 1 part in nitro- hydrochloric acid 8 parts, concentrating and crystallizing. This salt is a Trichloride of Gold. It is used in photography, etc., the official Chloride of Gold and sodium is made by mixing equal parts of this with dry chloride of sodium. Monochloride of Gold— AuCl — may be made by heating the trichloride to about 440 F. until fumes of chlorine cease to be evolved. 255. Cyanide of Gold— AuCy 3 .— By adding a solution of Cyanide of potassium to a solution of Chloride of Gold as long as a precipitate is formed, washing and drying the precipitate. 256. Iodide of Gold— Aul 3 .— By gradually adding a solution of Chloride of Gold to a solution of iodide of potassium, and drying the precipitate. Used as an alterative ; dose about T V grain. 257. Oxides of Gold.— Gold forms with alkaline bases a monoxide Au 3 0, and a trioxide Au 2 3 . Sometimes it is given as an alterative in doses of tV to X A g rain - 258. Sulphide of Gold— Au 2 S 3 .— By passing a current of sulphuretted hydrogen through a solution of Chloride of Gold in water, collecting and washing the precipitate. BALSAMA — BALSAMS. Balsams or Balms (Fr. Baumes), as they are known in phar- macy, embrace a variety of natural and prepared substances supposed to possess healing or soothing virtues. As popularly known, they include not only the natural Balsams obtained from balsam-bearing trees, but a variety of preparations rang- BALSAMS. 181 ing in consistence from tinctures to ointments, which have derived the name of " Balsam " from properties claimed for them by their originators. In this article we shall include only the Balsams proper, and those prepared, which have by long usage become most familiar as " Balsams," in a pharmaceutical sense. Other Balsams will be found under other headings, where they more properly belong, as Friar s Balsam (see Com- pound Tincture of Benzoin), Turlington s Balsam (see Proprie- tary Medicines), Cough Balsam (see Standard Remedies), etc. In French Pharmacy a great number of preparations are classed with Balsams which properly belong elsewhere. True Natural Balsams. The True Natural Balsams may be defined as oleo-resinous substances, either semi-liquid, or semi-solid, or solid, obtained from plants, and containing benzoic, cinnamic, or some anal- agous acids. Only seven substances are thus classed, and some of these are not known commercially as Balsams. They are as follows : 259. Balsam of Calaba — Tacamahaca. — This is obtained from the trunk, branches and leaves of Calophyllum Calaba, or Santa Maria tree. It is a liquid, at first white, but soon becomes olive-green, and is sometimes called Green Balsam. A similar Balsam is obtained from chloroxylon verti- cillatum of Peru, which is popularly called Green Balsam (of Peru). They contain benzoic acid. 260. Balsam of Peru. — A liquid balsam, obtained from Myroxylon Pereira, containing cinnamic and benzoic acids, and some other allied compounds. A solid or semi-solid variety is also imported, but not fre- quently kept by druggists. Uses. — Balsam of Peru is used as a stimulant to the mucous membrane, and in stimulating ointments, etc. Also as a preservative for fats. As found in the market, it is frequently adulterated with or entirely fabricated from other substances. 261. Balsam of Tolu.— A Balsam obtained from Myroxylon Toluifera, containing cinnamic and benzoic acids, volatile oils, called benzyl benzoaie, C 7 H 5 (C 7 H 7 )Oj;, and benzyl cinnamate, Q v W~S£^-l)0», a terpene named Tolene, C 10 H, „, and resins. It is a semi-liquid, as first obtained from the trees, but concretes into a solid resinous mass by standing. Uses.— It is much used in cough remedies as an agreeable aromatic, and in the form of tincture and syrup is frequently prescribed. 182 BALSAMA — BALSAMS. 262. Benzoin, or Benjamin. — A solid Balsamic resin, obtained from Styrax Benzoin, containing benzoic acid, cinnamic acid, a fragrant volatile oil and resins. Vanillin is also found in some varieties. Uses.— In pharmacy it is used as a preservative for fats and in making several preparations, and in medicine as an aromatic stimulant and expecto- rant. The dose is 10 to 15 grains. Benzoyl — C 7 H 5 0. — This is the radical of an extensive series of aromatic compounds which are derived directly or indirectly from Benzoin. Benzoic Acid, HC-H-O a , is obtained from benzoin and other balsams by sublimation, but is now mostly made artificially from coal-tar hydro-carbons. It forms with bases a class of salts called Benzoates, now considerably used in kidney diseases. It is stimulant, expectorant and antiseptic ; the usual dose being from 5 to 10 grains in mucilage or syrup. 263. China Varnish Balsam. — An aromatic, varnish-like exudation, ob- tained from Augia Sinensis, containing benzoic acid and other similar com- pounds. It is used by the Chinese for preparing the varnish or lacquer so celebrated in that country. 264. Styrax or Storax. — A Balsam prepared from the inner bark of Liquidambar Orientalis, containing cinnamic and benzoic acids, Styracin, C 9 H 7 (C 9 H 9 )0 2 , Storecin C 36 H5 8 3 , Ethyl Cinnamate C 9 H 7 (C 2 H 5 )0 2 , Phenyl-propyl Cinnamate C 9 H 7 (C 9 H l7 )0 2 , Styrol C 8 H 8 , resins, etc. It is a semi-liquid grayish-green Balsam, used in pharmacy in making com- pound tincture of benzoin, and as a preservative for fats, etc. Also used in perfumery. 265. Liquidambar, or Sweet Gum. — A balsamic exudation from Liquid- ambar Styracifiua. The constituents and properties of this Balsam seem to be identical with Storax, but it differs from it in being, as found in the market, a resinous gum instead of a liquid. Other Natural " Balsams." The following natural exudates are commercially known as Balsams, but pharmaceutical^ are classed with oleo-resins, turpentines, resins, etc., under which headings they will be more fully noticed. Balsam Copaiba, Copaiba Balsam or Copaiba. Balsam of Fir, Canada Balsam or Canada Turpentine. Gurjun Balsam, or Wood Oil. Hungarian Balsam. Japan Varnish Balsam or Japan Lacquer, Balsam of Mecca or Balm of Gilead. Balsam Rackasira. Balsam of Riga or Carpathina Balsam. Turpentine Balsam, Turpentine Gum, or Gum Thus. BALSAMA — BALSAMS. 183 Factitious Balsams. It is customary with dealers, for some purposes, to sup- ply imitations of several of the more expensive Balsams. The practice is not to be commended, but the formulae for these fabrications may be interesting to our readers. 266. Factitious Canada Balsam. White Resin, 4 pounds av. Oil of Turpentine, 1 gallon. Linseed Oil 8 fl.ounces. Oil of Lemon, 30 minins. Oil of Rosemary 20 minims. Dissolve the resin in the oil of turpentine and add the other oils. 267. Factitious Balsam Copaiba. Benzoin, powdered, 4 ounces av. White Resin, 3 pounds av. Canada Balsam 2 pounds av. Castor Oil, 1 gallon. Oil of Juniper, 2 fl.ounces. Oil of Savin, 1 fl. ounce. Oil of Orange, 30 minims. Oil of Lemon, 30 minims. Melt the resin, add the benzoin and part of the Castor Oil, and mix well together ; then add the remainder of the Castor Oil and the Canada Balsam, and when nearly cool the remaining oils. Let settle and strain. Diluted or Reduced Balsam Copaiba. — Balsam Copaiba is often sold diluted with Castor Oil or Canada Balsam, or other similar substances. .Such practice should be discountenanced, but the diluted article is, perhaps, better than the factitious. 268. Factitious Balsam of Mecca or Balm of Gilead. The true Mecca Balsam or Balm of Gilead is an oleo-resin, obtained from the Balm-of-Gilead tree of the East, but the factitious Balsam is much more frequently sold and used. It may be made as follows : Benzoin, coarsely powdered 4 ounces. Liquid Storax 3 ounces. Balsam Tolu 2 ounces. Canada Balsam, 30 ounces. Mix together in a closed vessel and heat by water-bath with frequent agita- ion until the substances are well incorporated. When cold pour off the clear 184 BALSAMA — BALSAMS. portion from the sediment and add 10 minims each oils of Lemon, Cassia, Nutmeg, Rosemary and Vanilla, 269. Factitious Balsam of Peru. Benzoin, in coarse powder 12 ounces. Balsam Tolu 4 ounces. Liquid Storax, Vz ounce. Alcohol, a sufficient quantity. Mix the Balsams with 2 pints of Alcohol and macerate by the heat of a water- bath until the Balsams are dissolved as much as possible ; strain the liquid while hot, and add sufficient Alcohol to the strained liquid to make 2 pints. Diluted or Reduced Balsam of Peru.— This may be made by taking Balsam of Peru 3 parts, Balsam of Tolu 2 parts, and Alcohol enough to make a liquid of the proper consistence (about 2^ parts). 270. Factitious Balsam of Tolu. Balsam of Tolu is frequently adulterated with resin or other similar sub- stance, but is seldom made up entirely from foreign substances. An old formula for making Factitious Balsam of Tolu is as follows : Orange Shellac and White Sugar equal parts, Alcohol sufficient to soften the Shellac, Tincture of Benzoin, Oil of Cassia, Oil of Nutmeg, and Tincture of Vanilla sufficient to flavor ; warm and work them well together. Balsamic Compounds. The following compounds are those which may properly be classed as Balsamic compounds pharmaceutically. They do not include the ointments that are popularly known as " Bal- sams," nor the proprietary preparations called "Balsams," nor such tinctures or other preparations known as " Balsams," that more properly come under other headings. 271. Balsam of Honey. {Pectoral Balsam?) Balsam of Tolu, 1 ounce av. Honey, strained, 2 x / 2 ounces av. Opium, in powder, 60 grains. Turmeric, in powder, 30 grains. Alcohol, 9 fl. ounces. Water, 1 fl. ounce. Mix, macerate for one week and filter. Used for coughs, hoarseness, etc. Dose, 20 to 40 drops. JALSAMA — BALSAMS. 185 272. Balsam of Guaiacum. Guaiac Resin, 8 ounces av. Balsam of Peru, 90 minims. Alcohol, 9 fl. ounces. Water, I fl.ounce. Mix, macerate for one week and strain. An old remedy for rheumatism, ague, etc. Dose, 20 to 60 drops. 273. Green Balsam. {Balsam Viride.) Besides the natural Green Balsams previously mentioned, the following is sometimes used : Linseed Oil, 12 ounces av. Gum Elemi, 2 ounces av. Verdigris, in powder, 3 drachms. Heat the Oil and the Gum together, add the Verdigris, and after standing a few days pour off the liquid. Used externally as a stimulating application to indolent sores. 274. Goulard's Balsam. Balsam Saturnine. Acetate of Lead, dry, in powder, . . 2 ounces av. Oil of Turpentine, I pint. Heat the Oil, and triturate the powder with it in a hot mor- tar until cool, then pour off the clear portion. Used exter- nally for sores, ulcers, etc. 275. Balsam of Metz. Aloes, in fine powder, 120 grains. Verdigris, " 180 grains. Sulphate of Zinc," 90 grains. Turpentine (Gum Thus), 2 tr.ounces. Oil of Juniper, 4 fl. ounces. Oil of Cloves, 1 fl. drachm. Oil of Laurel Berries, 1 fl.ounce. Olive Oil, ^y z fl. ounces. Linseed ( )il 41/ fl. ounces. L86 BALSAMA — BALSAMS. Melt the Turpentine, add the oils, except the Juniper and Cloves, stir in the powder, put in a bottle, and when cool add the oil previously omitted, and shake well. This is used as a dressing for ulcers, sores, etc. 276. Balsam of Sulphur. [Sulphurated Oil.) This preparation is known pharmaceutical^ as Sulphuratum Oleum or Sulphurated Oil, but is more commonly known and called for as Balsam of Sulphur. It is made as follows: Sulphur, sublimed 3^ ounces. Linseed Oil 21 ounces. Put the Oil in a capacious iron kettle, add the Sulphur, and boil gently, with continual stirring, until the Sulphur is entirely dissolved and a uniform liquid is obtained. This is used externally, and, in combination with other sub- stances, is often prescribed for internal use. 277. Balsam of Turpentine. Common Resin, 1 pound av. Oil of Turpentine, I pint. Melt the Resin, remove from the fire, and while cooling add the Oil of Turpentine. This is sometimes sold as Peckham's Balsam (see Proprietary Medicines). 278. Universal Balsam or Balm. Benzoin, in powder 6 ounces. Balsam of Tolu 3 ounces. Storax, ... 2 ounces. Olibanum (Frankincense), 2 ounces. Myrrh, in powder, 2 ounces. Socotrine Aloes, in powder, 3 ounces. Alcohol, 1 gallon. Mix them well together, and keep in a warm place for sev- eral weeks, or heat gently in a closed vessel by a water-bath until the gums are dissolved, then strain or filter. This is given internally in doses of 20 to 40 drops on sugar, 187 or is used externally for cuts or wounds. It is similar to com- pound Tincture of Benzoin. BARIUM. Symbol, Ba ; Atomic weight, 137; Sp. gr., 4.70. Barium is a metallic element closely related to calcium and magnesium. It is not found uncombined in nature but may be obtained from its oxide baryta by heating it in an iron tube through which the vaper of potassium is conveyed. The reduced Barium is then extracted from the mixed residuum in the tube by treating with mercury, and the mercury is afterward driven off by distillation in a vapor of mineral naphtha. The metal was first isolated by Sir H. Davy, in 1808. It is of a greenish silver-white lustre, malleable, decomposes water and gradually oxidizes in the air, forming baryta or barytes, BaO. Salts of Barium. No Salts of Barium are official, but the chloride and nitrate are used for making test solutions. In the industrial arts several of the Salts of Barium are extensively employed. Salts are formed with nearly all the acids, and negative ele- ments. The following are the most important : 279. Barium Acetate — Ba(C 2 H 3 2 ) 2 . — Made by neutralizing acetic acid with carbonate of barium evaporating and crystallizing. 280. Barium Arseniate — Ba s (As0 2 ) 2 . — By precipitating a solution of arseniate of potassium with a solution of Chloride of Barium. Given in skin diseases, in doses of -fc to % grain. 281. Barium Benzoate — Ba(C 7 H 5 2 ) 2 + 2H 2 0. — By neutralizing a solution of benzoic acid with Carbonate of Barium, evaporating and crystallizing. 282. Barium Bromide — BaBr 2 2H 2 0. — By saturating a solution of caustic baryta with hydrobromic acid, evaporating and crystallizing. 283. Barium Carbonate — BaC0 3 . — This is found abundantly in Nature, the native carbonate being called Withcrite. This is sufficiently pure for industrial and commercial purposes. It is used as the manufactur- ing basis of most of the Barium Salts. It is very poisonous. May be employed as a rat poison or for other similar purposes. It is also used in 188 BARIUM. face powders and liquid cosmetics, and is considerably used in place of car- bonate of lead to adulterate paint. 284. Barium Cloride — BaCl 2 2H 2 0. — By dissolving Carbonate of Barium in hydrochloric acid, evaporating and crystallizing. Used for making test solution (see solutions), and in medicine as an alterative, in doses of % to y z grain, also externally in solution. 285. Barium Chromate — BaCr0 4 . — By adding baryta water (solution of Caustic Barium) to a solution of chromate of potassium, washing and drying the precipitate. 286. Barium Hydrate — Ba(HO) 2 . — By digesting caustic baryta (Barium Oxide ) with a little water, the elements of water are assimilated, yielding Hydrate of Barium, or it may be crystallized from baryta water by evapora- tion. Baryta Water is made by dissolving the hydrate thus formed in water to saturation. 287. Barium Iodide — Ba 3 I. — By adding iodine gradually, in excess, to a solution of Sulphate of Barium. When the reaction is finished filter the solution, evaporate and crystallize. 288. Barium Nitrate — Ba(N0 3 ) 2 . — By decomposing a solution of nitrate of sodium with a solution of Chloride of Barium, collecting the precipitate, washing and drying. This is used for making a test solution. (See solutions.) 289. Barium Oxalate — BaC 2 4 . — By precipitating a solution of Oxide of Barium with a solution of oxalic acid, collecting, washing, and drying. 290. Barium Oxide — Baryta, Barytes, Caustic Baryta — BaO. — This is a very caustic, corrosive, alkaline substance, which may be made by calcining some of the Salts of Barium, or decomposing Solution of Sulphide of Barium by oxide of zinc. Peroxide of Barium Ba0 2 is prepared by passing a stream of oxygen or air through a tube, containing baryta heated to dull redness. By treating with diluted hydrochloric acid it yields solution of peroxide of hydrogen (H 2 2 ). 291. Barium Sulphate — BaS0 4 . — This is found native or may be pre- pared by decomposing a solution of Chloride of Barium with sulphuric acid, collecting the precipitate, washing, and drying. Sulphide of Bar item — BaS — and Sulphite of Barium BaS0 3 , are other compounds of sulphur and oxygen with Barium sometimes used. Some of the Barium Salts are used in combination with chlorides for making colored fires of a greenish color, or giving a greenish color to flame. Antidotes. — For poisoning by soluble Salts of Barium any of the soluble sulphates in solution may be given, as Epsom or Glauber's salt, alum, etc. They form insoluble Sulphate of Barium. BENZINUM. BENZOLUM. 189 292. BENZINUM — BENZIN, U. S. Petroleum Benzin, Petroleicm Ether. "A purified distillate from American Petroleum, consisting of hydrocarbons, chiefly of the marsh-gas series (C 5 H 1S ; C 6 H 14 and homologous compounds), having a sp. gr. from 0.670 to 0.675, and boiling at 50 to 6o° C. (122 to 140° F.)" It is soluble in 6 parts of Alcohol. The preparation thus described in the U. S. P. is obtained by fractional distillation from Petroleum, and is known in the market as "Naphtha." It is intermediate between gasoline and benzine, and consists mainly of the hydrocarbons pentane and hcxaue. Gasoline, which is of less sp. gr., is frequently used in place of it for pharmaceutical purposes. It is quite different from the benzene obtained from coal-tar, which is more commonly known as benzol. It is a powerful solvent of fixed oils, resins, caoutchouc, paraffin, etc., and is used in pharmacy for extracting oleo- resins, for removing fixed oils from certain drugs, previous to percolation, for purifying some solutions and for other pur- poses. Either alone or combined with other substances, it is used for removing grease spots, etc., from clothing. Benzine. — The hydrocarbon distilled from petroleum, and known commercially as Benzine, is a heavier product than Benzin as above described. Its sp. gr. being from 0.725 to 0.737. It is the last of the series of hydrocarbons which distills before illuminating oil begins to be run. It has a strong odor, and was formerly used considerably in place of turpentine for painting and similar purposes. It should not be confounded with Benzene, which is obtained from coal-tar. BENZOLUM BENZENE — BENZOL. Hydride of Phenyl. (HC fl H 5 )C fl H 6 . This is the first member or basis of the important homolo- gous series of hydrocarbons known as the Aromatic or Benzene 19( ) B I NZOLU M — BENZENE — BENZOL. Series (C„H 2 „_ 6 ). Its sp. gr. is 0.85 to 0.90, and it boils at 8o°4 to 85 C. (177 to 185 F.). It is chiefly derived from coal- tar by distillation, but is also obtained from petroleum and other hydrocarbons, and from benzoic acid, from which it derives its name. It was first discovered by Faraday in 1825, in the products of the destructive distillation of whale oil, and afterward, by Mitscherlich, was obtained from benzoic acid, by distilling with hydrate of lime. In 1849, Mr. C. B. Mansfield discovered its presence in coal-tar naphtha, from which the commercial Benzol is now chiefly obtained ; but recently its manufacture from petroleum has assumed considerable com- mercial importance. In the arts the importance of Benzene cannot be overesti- mated. It is the commercial basis of aniline, of nitrobenzol, and of a great variety of products of chemistry and pharmacy which, at the present time, are attracting much attention. For further information on this subject, our readers are referred to Fenner's Practical Chemistry. Benzene or Benzol should not be mistaken for Benzine, which is distilled from petroleum, as they are not identical in com- position. With other hydrocarbon bases Benzene forms a series of compounds classed as the Aromatic or Benzene Series, the more important of which are : C e H e Benzene \ C 6 H 6 . C 7 H 8 Toluene or Methylbenzene j C 6 H 5 (CH S ). C 8 H 10 Xylene or Ethylbenzene (and other isomers) C 6 H 5 (C 3 H 5 ). C 9 H 1S Propylbenzene (and other isomers) C 6 H 5 (C 3 H 7 ). C 10 H 14 Isobutylbenzene (and other isomers) j C 6 H 5 .C 3 H 3 (CH 3 ) 2 . C 1X H 16 Isoamylbenzene (and other isomers) ! C 6 H 5 .C 3 H 5 (CH 3 ) 2 . etc. etc., etc. The chief product of Benzene, in a commercial sense, is its nitrate or nitrobenzol. 293. Nitrobenzol — C 6 H 5 N0 2 — Artificial Oil of Bitter Almonds is made by adding Benzol in small portions to fuming nitric acid. A violent reaction occurs, and a dark-red liquid results. Water is added, and an oily liquid precipitates ; the water is poured off and the oily precipitate repeatedly washed with fresh water. It is chiefly used for scenting soaps and for the manufacture of aniline. It should never be used for flavoring medicinal preparations. BISMUTHUM — BISMUTH. 191 BISMUTHUM — BISMUTH. Symbol, Bi ; Atomic Weight, 210 (Dumas); sp. gr. 9.82. Bismuth is a metallic element, classed, on account of its analogies, with arsenic and antimony. It is found in nature in a metallic state and combined with other metals and ores. In appearance it closely resembles antimony. It is crystalline, brittle, pulverizable, and has a reddish silver color. It melts at 264 C. (507 F.) and is readily obtained from its ores by fusion. Upon solidifying after fusion it expands -^ of its volume. Bismuth is used in the arts chiefly as an alloy with other metals. In pharmacy it is used for the preparation of many of its salts, which are employed in medicine, and also as ingre- dients in toilet powders and liquid cosmetics. The following are the chief alloys of Bismuth : 294. Fusible Metal. — With lead and tin Bismuth forms alloys known as Fusible Metal, which have a very low melting point, the temperature required to fuse them being less than of boiling water. Newton's Fusible Metal consists of Bismuth 8 parts, lead 5 parts, and tin 3 parts. It fuses at 94°5 C. (202 F.) Darcet's Fusible Metal consists of Bismuth 2 parts, lead 1 part, tin 1 part. It fuses at 93 C. (i99°2 F.) Another combination of the three metals liquefies at a still lower temperature. When Cadmium is added the fusibility of these alloys is increased. Wood's Fusible Metal, which consists of 1 to 2 parts of cadmium, 2 of tin, 2 of lead, and 7 to 8 parts of Bismuth, melts between 66° and 71° C; and another described by Lipowitz, consisting of 8 parts of lead, ) 5 of Bismuth, 4 of tin, and 3 of cadmium, softens at 55° and liquefies at 6o° C. These alloys are sometimes used as safety plugs for steam apparatus, but are chiefly valuable in experiments. 295. Soft Solder for Mending Pewter and other ware, melting at a low temperature, is made by melting together 1 part of Bismuth, 2 of tin and 1 of lead. This same composition is also used as a bath for tempering steel, and for making the moulds for cakes of fancy soap, etc. 296. Electrotype Moulds.— An alloy for electrotype moulds may be made with Bismuth 8 parts, lead .S and tin 3. It melts at 228 F., and is allowed to cool until it becomes pasty, when the warmed cut, medal or other device is pressed upon it and kept in contact until cool. 297. Bismuth Amalgam is formed by adding 2 parts of hot Mercury to 1 part of fused Bismuth. I >ther alloys of Bismuth with silver, platinum, copper or other metals may be made but they have no industrial application. L92 BISMUTHUM —BISMUTH. 298. Bismuthum Purificatum, Br. Purified Bismuth. Commercial metallic Bismuth contains many impurities which render it unfit for use in making medicinal salts of Bis- muth. The Br. P. therefore directs that it be purified as follows : Bismuth 10 ounces av. Cyanide of Potassium, y 2 ounce av. Sulphur 80 grains. Carbonate of Potassium recently ignited, ) of each a Carbonate of Sodium recently ignited, ) sufficiency. " Melt the Bismuth in a crucible, add the Cyanide of Potas- sium and Sulphur previously mixed. Heat the whole to low redness for about 15 minutes, constantly stirring. Remove the crucible from the fire, and let it cool until the flux has solidified to a crust. Pierce two holes in the crust aud pour the still fluid bismuth into another crucible. Remelt this par- tially purified bismuth with about five per cent, of a mixture of equal parts of the dried carbonates of potassium and sodium, heating to bright redness and constantly stirring. Remove the crucible from the fire, cool and pour out the bismuth into suitable moulds." Br. This process entirely frees it from arsenic and other impurities, and fits it for use in making medicinal salts. Official Salts of Bismuth. The following are the Salts of Bismuth which are official in the leading pharmacopoeias. They are astringent and tonic, and are also used internally and externally to prevent irritation and cover irritated surfaces : 299. Bismuthi Carbonas, Br. Carbonate of Bismuth — Oxycarbonate of Bismuth. (Bi 2 2 C0 3 ) 2 .H 2 0. The 1885 Br. P. gives the following formula for the prepara- tion of this salt, which differs from the U. S. .^carbonate of BISMUTHUM — BISMUTH. 193 Bismuth only in containing one volume less of C0 3 in its molecule : Purified Bismuth in small pieces, ... 2 ounces av. Nitric Acid, 4 fl. ounces. Carbonate of Ammonium, 6 ounces av. Distilled water, a sufficiency. " Mix the Nitric Acid with three ounces of distilled water and add the bismuth in successive portions. When efferves- cence has ceased, apply for ten minutes a temperature approach- ing that of ebullition, and afterwards decant the solution from any insoluble matter that may be present. Evaporate the solution until it is reduced to two fi. ounces, and add this in small quantities at a time to a cold filtered solution of the car- bonate of ammonium in two pints of distilled water, contin- ually stirring during admixture," collect the precipitate on a calico filter, wash with distilled water, press and dry at a tem- perature not exceeding i5o°F. Dose, 5 to 20 grains. 300. Bismuthi Citras. Citrate of Bismuth. The U. S. P. directs this to be made by boiling 10 parts of subnitrate of bismuth and 7 parts of citric acid with 40 parts of distilled water until a drop of the mixture yields a clear solution with water of ammonia, and then adding 500 parts of distilled water, allowing the suspended matter to deposit, washing the precipitate with distilled water, and drying at a gentle heat. The Br. P. directs 51/ ounces av. of subnitrate of Bismuth to be dissolved in i i fl. ounces (or a sufficiency) of nitric acid by the aid of heat. Water is then added until the solution remains permanently slightly cloudy; 8 ounces av. of bicar- bonate of sodium is then dissolved in distilled water, 4 ounces av. of citric acid is added, and the solution boiled until all the gas is expelled. This solution is then added to the solution of Bismuth, and the whole heated to boiling, with occasional 194 BISMUTHUM — BISMUTH. stirring. When cold the liquid is poured off and the precipi- tate washed and dried over a water-bath. Uses. — This salt is seldom employed in medicine, but in pharmacy is used for preparing Citrate of Bismuth and Am- monium, U. S. P. and solution of Bismuth and Ammonium. Br. P. 301. Bismuthi et Ammonii Citras. Citrate of Bismuth and Ammonium. The U. S. P. directs this to be made by mixing 10 parts of Citrate of Bismuth with 20 parts of distilled water and gradu- ally adding water of ammonia until the salt is dissolved and the liquid has only a faintly alkaline reaction. The solution is then to be filtered, evaporated to a syrupy consistence, and spread upon plates of glass, so that in drying the salt may be obtained in scales. The Br. P. process is in effect the same, the official solution of Citrate of Bismuth and ammonium being evaporated, etc., as above. This is the only soluble Salt of Bismuth, and in pharmacy is considerably used in making elixirs and other preparations requiring Bismuth in solution. It is sometimes prescribed in powders, etc., the dose being from I to 3 grains. 302. Bismuthi Oxidum, Br. Oxide of Bismuth. Bi 3 3 . Subnitrate of Bismuth 1 ounce av. Solution of Soda, 5 fl. ounces. Mix and boil for five minutes, then, having allowed the mixture to cool and the oxide to subside, decant the super- natant liquid, wash the precipitate thoroughly with distilled water, and, finally, dry the oxide by the heat of a water-bath." This salt is also known by the names Teroxide of Bismuth and Protoxide of Bismuth, or Bismuthous Oxide. BISMUTHUM — BISMUTH. 195 Hydrated Oxide of Bismuth may be made by gradually dropping an acid solution of Bismuthous Nitrate into a con- centrated solution of potassium hydrate (solution of potassa), entirely free from carbonic acid, and washing and drying the precipitate. Bismuthic Oxide or Anhydride — Bi 2 5 — {Bismuthic Acid) is prepared by suspending Bismuthous Oxide in a strong solu- tion of potassa and passing pure chlorine gas through the mixture until it is decomposed. The powder is then treated with nitric acid, washed with cold water and dried. Uses. — Oxide of Bismuth has similar properties and uses as the subnitrate. The dose is from 5 to 15 grains. 303. Bismuthi Subcarbonas, U. S. Subcarbonatc of Bismuth. (BiO) 2 .C0 3 .H 2 0. The present U. S. P. gives no process for preparing this salt, but it differs in composition from the Carbonate of Bis- muth (299) only in containing one more volume of C0 3 in its molecule. The process formerly official was to dissolve 2 tr.ounces of Bismuth in 43^ tr.ounces of nitric acid mixed with 4 fl. ounces of distilled water, and set aside for 24 hours ; the solution was then diluted with 10 fl. ounces of distilled water, and after 24 hours filtered ; 4 pints of distilled water were then added to the filtrate and the solution precipitated with 5 fl. ounces of water of ammonia. The precipitate was then to be washed and dissolved in 4 tr.ounces of nitric acid diluted with 4 fl. ounces of distilled water and after 24 hours filtered ; IO tr.ounces of carbonate of sodium are then to be dissolved by heat in 12 (bounces of distilled water, and the solution filtered and when cold the solution of Nitrate of Bismuth gradually added to it with constant stirring. The mass is then to I"- washed with distilled water until the washings are tasteless, then dried on bibulous paper with gentle heat, and rubbed to a powder. Uses. — -Astringent and tonic, similar to the subnitrate. I )ose 5 to 10 grains. 196 BISMUTHUM — BISMUTH. 304. Bismuthi Subnitras. Sub nit rate of Bismuth — Oxy nitrate of Bismuth. BiON0 3 .H s O. No process for making this salt is now given in the U.S. P., but it may be made by the former official process, which is the same as for making the Subcarbonate of Bismuth, except that the solution of Acid Nitrate of Bismuth first made is precipitated with the solution of carbonate of sodium, and the second acid solution of Bismuth is precipitated with water of ammonia. The Br. P. directs it to be made as follows: Purified Bismuth, in small pieces, . 2 ounces av. Nitric Acid, 4 fl. ounces. Distilled Water, a sufficiency. " Mix the nitric acid with three ounces of distilled water, and add the Bismuth in successive portions. When efferves- cense has ceased, apply for ten minutes a temperature ap- proaching that of ebullition and decant the solution from an)- insoluble matter that may be present. Evaporate the solution until it is reduced to two fl. ounces, and pour it into half a gallon (80 fl. ounces) of distilled water. When the precipitate which forms has subsided, decant the supernatant liquid. Wash the precipitate, press and dry it at a tempera- ture not exceeding i5o°F. Uses. — Subnitrate of Bismuth is used in pharmacy as the basis of many of the other Bismuth salts and for making various preparations. In medicine it is extensively employed as an astringent, tonic, and sedative. Dose, from 2 to 10 grains. Other Salts of Bismuth. Besides the foregoing official Salts of Bismuth, the following arc sometimes used : 305. Bromide of Bismuth— BiBr 3 . — Made by adding bromine in excess to Metallic Bismuth, and when their combination is complete, collecting the steel-gray mass. 306. Basic Chloride of Bismuth — Bi s Cl 3 . Made by dropping hydro- chloric acid into a solution of Nitrate of Bismuth, collecting, washing and drying the precipitate. This is known as Subchlcride of Bismuth or Pearl Powder, and is considerably used in face powders and liquid cosmetics. BISMUTHUM — BISMUTH. BORON. 197 307. Oxychloride of Bismuth — BiOCl. — By pouring a solution of Bismuth in nitric acid into a solution of chloride of sodium, collecting the precipitate, washing and drying. 308. Terchloride of Bismuth — B i C 1 3 . — By mixing 2 parts of powdered bichloride of mercury with 1 part of powdered Bismuth, and heating until the mercury is driven off. 309. Chromate of Bismuth — 3 Bi 2 3 2CrO . — By adding a solution of Nitrate of Bismuth to a moderately concentrated solution of bichromate of potassium in slight excess, and collecting the precipitate. 310. Lactate of Bismuth. — By mixing the freshly precipitated moist Oxide of Bismuth, prepared from 10 parts of Subnitrate of Bismuth, by boiling with excess of solution of soda, with 9 parts of lactic acid, and drying the mass on a water-bath. 311. Oxalate of Bismuth — CgBigOi 2 .I5H 3 0. — By mixing Nitrate of Bismuth with a solution of oxalic acid, and collecting the precipitate. 312. Nitrate of Bismuth— Bi(N0 3 ) 3 — Ter- or Tris-Nitrate of Bis- mut/i. — Made by dissolving Bismuth in sufficient nitric acid to effect its solution, adding to the solution half its volume of distilled water, filtering through glass-wool, evaporating and crystallizing. This is used for making some other Salts of Bismuth and for hair dye, etc. 313. Salicylate of Bismuth. — By dissolving Nitrate of Bismuth in glycerin, and adding to it a concentrated solution of salicylate of sodium, then collecting the precipitate. 314. Tannate of Bismuth. — By dissolving 22 parts Nitrate of Bismuth in the least requisite quantity of nitric acid diluted with half its weight of water, pouring the solution into an excess of solution of soda, collecting the precipitate, washing and triturating the moist precipitate with 10 parts tannin, rubbed with water, straining and drying. 315. Tartrate of Bismuth.— By adding a hot, concentrated solution of tartaric acid to a solution of Oxide of Bismuth in nitric acid, and washing the precipitate with an aqueous solution of tartaric acid. 316. Valerianate of Bismuth.— By dissolving Nitrate of Bismuth in the least requisite quantity of nitric acid, diluted with half its weight of water, then adding a concentrated solution of valerianate of sodium, washing the precipitate with water mixed with valerianic acid, and drying by gentle heat. BORON. Symbol, B; Atomic weight, i I ; sp. gr. 2.6s. The element Boron is always found in nature associated with >ther substances, either as boric acid or a salt ol boric acid. 198 BORON. Chemists have succeeded in obtaining an amorphous modifi- cation of Boron by heating boric anhydride, B 2 3 , with sodium, which decomposes it. The sodium salt is then washed out, leaving a dark, brown powder. A crystalline modification is made by reducing the anhydride or oxide (B 2 3 ) by the aid of aluminium at a very high temperature; then allowing to cool. The crystals thus produced are brownish, having a luster, refracting power and hardness nearly equal to the diamond ; and are only slightly oxidized at the temperature at which diamond burns. In many respects Boron resembles carbon and silicon, and is therefore classed with them, chemically. But few Boron compounds are used in pharmacy, only two being official, viz. : Boric Acid and Borax or Borate of Sodium. 317. Acidum Boricum. Boric Acid — (Boracic Acid). H3BO3. Boric Acid is produced by decomposing Borax with sulphuric or hydrochloric acid. 2 parts of borax are dissolved in 8 parts of boiling water, and sulphuric acid added until the solution is distinctly acid. This requires about 1 part of the acid. As the solution cools, crystals of Boric Acid are deposited, which may be collected and washed on a filter with a little cold water. The crystals may be further purified by dissolving in boiling water and recrystallizing. It combines with some bases, form- ing Borates, and unites with other acids to form Boro-com- pound salts, as Boro-tartrate of Potassium, etc. Metaboric Acid — HB0 3 — is prepared by heating Boric Acid to 38 C. (106 F.). Pyroboric Acid — H 2 B 4 0, — is made by heating Boric Acid for a long time to 6o° C. (140 F.). Uses. — Boric Acid has remarkable antiseptic and preservative virtues, and is now much employed in solution and in powder as an antiseptic, both externally and internally. It is also used as a preservative of solutions, juices, fruits, meats, foods, etc., 1 per cent, being generally sufficient for the purpose. Alcoholic solution of Boric Acid burns with a green flame. BORON. 199 318. Boro-glyceride. When heated with glycerin for a long time, Boric Acid parts with the elements of water and combines with the glycerin to form a new substance. It is made as follows : Boric Acid, in fine powder 62 parts. Glycerin (by weight), 92 parts. Heat the glycerin and gradually add the Boric Acid, con- tinuing the heat until it no longer gives off vapor or loses weight, and until it will readily dissolve in water at ordinary temperature. The operation requires 10 to 12 hours to com- plete. In the earlier part of the process steam is given off freely from the water, which is set free, being vaporized; later it escapes more slowly owing to the viscidity of the melted mass. The completed product when cool is a brittle and trans- parent solid of a light amber color and a shining fracture. It dissolves freely in warm water and in 5 parts of alcohol at 120° F. Uses. — Boro-glyceride is an antiseptic, astringent, and mild escharotic. In solution it is used as a surgical dressing and injection for removing diseased mucous secretions and pro- moting healthy action. 319. Sodii Boras. Borate or Biborate of Sodium — Borax. Na 2 B 4 7 .ioH 2 0. Borax is an alkaline salt found native in California, where immense deposits of it exist in the basins of evaporated lakes and pools. It is also obtained from Thibet, Persia, and other localities, and it may be made by combining Boric Acid with Soda. Uses. In the industrial arts Borax is extensively employed for mail}' purposes. It is used for washing and making some kinds of soap; as a flux, for refining metals and for welding, etc. In medicine it is used as an antacid and diuretic, and as 200 BROMUM — BROMINE. a soothing and healing wash for sores, especially for sore mouth. Its solution is used in pharmacy for saponifying fixed oils, whitening ointments, and for many purposes requiring a mild alkali. BROMUM — BROMINE. Symbol, Br. ; Atomic Weight, 79.8 ; sp. gr. 2.96. The element Bromine is a dense, dark-red, volatile liquid, boiling at 145.4 F. Its vapor is very irritating. It was dis- covered in 1826 by M. Balard, and on account of its analogies is chemically classed with chlorine and iodine. It is chiefly obtained from the mother liquor or bittern remaining after the crystallization of salt in salt-works. It combines energetically with other elements, forming salts called Bromides, many of which are extensively used in medicine. Uses. — In pharmacy Bromine is used for making bromides, hydrobromic and phosphoric acids, and other preparations. In medicine it is seldom used internally, but its solution is some- times employed as a cleansing or caustic wash, or as a gargle for diphtheria, etc. Like chlorine, it possesses wonderful bleaching properties, and is sometimes used for that purpose. The salts formed with Bromine and Bases are noticed under the bases with which the combinations are formed. The following are preparations of Bromine not otherwise classified : 320. Bromal — C 2 Br 3 HO. — This is an aldehyd derivative, prepared by the action of Bromine on ethyl alcohol. It is a colorless oily liquid, having S P- S r - 3'34. and boiling above 212° F. It is very irritating, therefore its use as a hypnotic or anaesthetic does not meet with favor. Combined with the elements of water, it forms a hydrate known as Bromal Hydrate, similar in appearance and uses to hydrate of chloral, but quite expensive and seldom used. 321. Bromoform — CHBr 3 . — This is a colorless volatile liquid, obtained by distilling alcohol combined with bromide of calcium. Its sp. gr. is 2.90, and it boils at 305.6 F. It is similar in properties and uses to chloroform, but is much more irritating, therefore is not much used medicinally. 322. Bromic Acid — HBr0 3 . — Made by decomposing bromate of barium with sulphuric acid, filtering the liquid from the precipitate and evaporating. BUTYL OR TETRYL. 201 Bromates are salts formed by the combination of this acid with bases. This should not be confounded with Hydrobromic Acid, HBr, which is a gas, the solution of which is official. (See page 59.) Some other combinations of Bromine are made, as Chloride of Bromine, Iodide of Bromi?ie, Bromacetic Acid, and other compounds with acids, but are seldom employed in pharmacy. BUTYL OR TETRYL. C 4 H 9 . Butyl is a gaseous radical — the fourth member of the hom- ologous series, C„H 2 „ +1 , known as the alcohol radicals. It is known in pharmacy only in its compounds, as butyric ether, butyric acid, etc. Commercially, its alcohol, ether or acid are obtained from amylic alcohol, rancid butter or cheese, etc. Its name is derived from butyrum (butter), from which it was first obtained. Its compounds with amyl and ethyl alcohols are considerably used in the manufacture of artificial fruit flavors — the buty- rate of ethyl, or butyric ether, being known as pineapple oil. Butyric acid combines with bases to form salts called Butyrates. The following are the principal combinations of Butyl employed in pharmacy, and not elsewhere classified : 323. Butyl-Chloral — C 4 H r> CI. ,0. — Made by passing dry chlorine gas into aldehyd, which forms Chloral and Butyl-chloral, the latter being a dense, oily liquid of strong odor, which, by shaking with an excess of warm water, dissolves, and upon cooling deposits Butyl Chloral-hydrate, formerly called Croton Chloral-hydrate. Butyl Chloral-hydrate is employed for the same purposes as Chloral-hydrate, but in considerably smaller doses. 324. Butyric Acid— HC., 1 1 7 2 . — This is present in rancid butter and cheese, which derive from it their peculiar odor. It is also obtained by the oxidation of butylic alcohol, C 4 H 9 HO, which is usually found in crude amylic alcohol or fousel oil ; and also in coal-tar. Butyric acid unites with organic radicals and metallic bases, forming Butyrates. 325. Butyrate of Amyl — ( _'- 1 1 , , C. l H 7 O s . — Made by heating together Butyric Acid, Sulphuric Acid and Amylic Alcohol, separating, distilling and purifying. 326. Butyrate of Ethyl — C..II ,< ,ll ; <>.,. By heating together Butyric Acid, Sulphuric Arid and Alcohol, separating, distilling and purifying. This is known commercially as Butyric Ether, 202 BUTYRUM. BUTTERINE. 327. Butyrum. Butter. In pharmacy fresh unsaltcd Butter is frequently used as a base for ointments, and although not official, it may often be advantageously employed. It consists of about 30 per cent, of olein, 68 per cent, of palmitin and stearin, and glycerides of butyric and other fatty acids. The process of making butter from cream by agitation is too well known to require description. In medicine Butter may be given as a food in place of cod liver oil. Medicines may be combined with it, or it may be made into an emulsion or jelly. 328. Butyrin.— By heating clarified Butter in a porcelain vessel for several days to 66° C, separating the oily portion, mixing it with an equal weight of alcohol and agitating it frequently for 24 hours, then pouring off the oily portion, evaporating it, treating the oily residuum with a little carbonate of magnesium, to remove free acid, separating, heating the remaining fatty matter in alcohol, filtering and evaporating. This is the chief neutral prin- ciple of Butter, and corresponds with Olein obtained from some other fats. 329. Butterine. A rtificial Butter — Oleomargarine. Although the manufacture of Butterine does not come within the province of the pharmacist, yet an outline of the process by which it is made may be of interest. Beef fat or suet is washed, cut up and melted at from 122 to 124 F. The liquid fat is drawn off, allowed to settle, strained or filtered, and kept at a temperature of' from 8o° to 90 F., until the stearine and palmatine mostly crystallize out. They are then separated from the liquid portion and pressed by hydraulic pressure in a room heated to about the same temperature (8o° to 90 F.). The portion that remains liquid at this tempera- ture consists of Oleomargarine. It becomes solid when cool. To make it into Butterine, it is churned while warm with milk (80 pounds of milk to 500 pounds of oil), and colored the desired shade, then run from the churn into a trough, where it is suddenly chilled by mixing it thoroughly with pounded CADMIUM. 203 ice, thereby preventing it from crystallizing. It is then salted and worked like butter, and flavored usually with a little extract of tonka-bean to give it the odor of new-mown hay. Its uses are similar to butter. CADMIUM. Symbol, Cd ; Atomic weight, 112 ; sp. gr., 8.7. Cadmium is a metallic element of a bluish-white color, resembling zinc, with which it is found associated in the ores, from which zinc is obtained. In distilling zinc containing cadmium, its vapor is lighter and passes over first. It is very malleable and ductile, and though it is similar to tin in general characteristics, it is harder and more tenacious. When heated to about 8o° C, it becomes very brittle, and may readily be powdered. Added to some other metals, in small proportions, it makes very fusible alloys (see page 191). Heated with oxygen, it forms an oxide, CdO. It combines with chlorine, iodine, bromine, and sulphur, forming salts, which are used in pho- tography and as pigments. The following are the principal Salts of Cadmium : 330. Bromide of Cadmium — CdBr 2 . — By adding a solution of bromide of potassium to a solution of sulphate of Cadmium, double decomposition occurs, sulphate of potassium being precipitated, and the solution of bromide of Cadmium poured off, concentrated and crystallized. Used in photog- raphy. 331. Carbonate of Cadmium — CdC< ),,. — By adding a solution of Nitrate of Cadmium to a solution of carbonate of sodium, collecting the precipitate, washing and drying. 332. Chloride of Cadmium — CdCl 2 . — By dissolving carbonate of Cad- mium in dilute hydrochloric acid, concentrating the solution and crystallizing. 333. Iodide of Cadmium — Cd I ... — By double decomposition between iodide of potassium and sulphate of Cadmium, the same as in making bro- mide of calcium, 'This is used for sensitizing photographic plates. It is also used in medicine as an alterative. 334. Nitrate of Cadmium — cd. \< • .. ■ By dissolving metallic Cadmium in nitric acid, concentrating and crystallizing. •204 < .KSHM. CALCIUM. 335. Oxide of Cadmium — CdO. — By igniting the nitrate or carbonate. A suboxide of Cadmium, Cd g O, is also known. 336. Sulphate of Cadmium — CdSO^Hj >. — By treating carbonate or oxide of Cadmium with diluted sulphuric acid. 337. Sulphide of Cadmium — CdS. — By passing a current of hydrosul- phuric acid through a solution of chloride of Cadmium. This is a brilliant yellow pigment. CESIUM. Symbol, Cs; Atomic weight, 132.7. The element Caesium is closely related to potassium and the other metals of the alkalies. It has not yet been isolated, but an amalgam has been obtained by submitting its chloride to electrolysis, employing a globule of mercury as the negative electrode. It is the most electro-positive metal known. Its chloride is the only salt which has been described, or which is known to pharmacy, and this is only interesting as a rare and expensive chemical. CALCIUM. Symbol, Ca ; Atomic weight, 40; sp. gr., 1.57. Calcium is a strongly positive element, occurring abundantly in nature as carbonate, phosphate, silicate, chloride, etc.; its compounds forming a large proportion of the crust of the earth. Its oxide is Calx or lime, and the salts of Calcium are generally, though improperly, called salts of lime. The metal Calcium was first obtained from lime by Sir H. Davy, in 1808. It is classed with barium, strontium and mag- nesium. It is of a light-yellow color, rather harder than lead, very malleable, ductile, and melts at about 500 C. Its salts are very extensively used in the arts and industries, and are considerably employed in pharmacy and medicine. The salts of Calcium in solution give a white precipitate with carbonate of ammonium, and, if concentrated, with sulphuric acid also. CALCIUM. 205 The following are the official salts of Calcium : 338. Calcii Bromidum, U. S. Bromide of Calcium. CaBr 2 . Hydrobromic acid, any convenient quantity. Precipitated chalk (calcium carbonate), a sufficiency. Add the precipitated chalk to the hydrobromic acid, a little at a time, until a portion remains undissolved after standing a few hours, then filter and evaporate the solution to dryness, stirring while drying to granulate the salt. Uses. — Bromide of Calcium is used as a hypnotic, and for nervous irritability, in doses of 20 to 60 grains. 339. Calcii Carbonas Praecipitatus. Precipitated Carbonate of Calcium — Precipitated CJialk. CaC0 3 . The U. S. P. does not give a process for making this salt, but the Br. P. directs as follows : Chloride of Calcium, 5 ounces av. Carbonate of Sodium, 13 ounces av. Boiling Distilled Water, a sufficiency. Dissolve the Chloride of Calcium and Carbonate of Sodium each in two pints of the water. Well mix the two solutions, and allow the precipitate to subside, collect on a calico filter, and wash it with boiling distilled water until the washings cease to give a precipitate with nitrate of silver, and dry the product at the temperature of boiling water, 2 I 2° F. Uses. — This powder is more commonly known as English precipitated chalk, and is much used in tooth powders, toilet powders, etc. It is also used ill medicine in the form of pow- ders, troches, etc., and is frequently employed for making chalk mixture, but is not considered so good for that purpose as prepared chalk. The dose is 10 to 30 grains or more. 206 CALCIUM. 340. Creta Prasparata. Prepared Chalk, Prepared Carbonate of Calcium. Although this substance is not classed in the pharmacopoeias under the heading Calcium, it properly belongs there, as it is " native, friable. Carbonate of Calcium, CaCOjj, freed from most of its impurities by elutriation." This is prepared from common chalk, which is native, friable, Carbonate of Calcium, by rub- bing it with a little water into fine powder, then transferring it to a large vessel nearly full of water, stirring thoroughly, and, after a moment, while the supernatant liquor is still turbid, pouring it off into another vessel. The coarser particles of chalk, which remain in the first vessel, are then treated again with water in the same manner, the liquid poured off and added to the portion formerly decanted. The suspended chalk is now allowed to subside, the water poured off, and the powder dried or made into little cones or "drops" by running through a paint mill. Uses. — Prepared chalk is an antacid, used medicinally almost altogether when Carbonate of Calcium is indicated. It is given in diarrhoea, acid stomach, etc. Also used in making toilet powders. Dose, 10 to 30 grains or more. Whiting is a cheap prepared chalk used for whitening walls, polishing, etc. 341. Calcii Chloridum. Chloride of Calcium. CaCl 2 . Chloride of Calcium may be prepared by neutralizing hydro- chloric acid with chalk or marble, adding a little solution of chlorinated lime and slacked lime to the solution, filtering, evaporating the filtrate to dryness, and then heating to red- ness. The fused salt thus prepared is used to dry gases, and in pharmacy as the basis of some other calcium salts. A solu- tion made with it is official in the Br. P. This salt should not be mistaken for chlorinated lime, which is more frequently called " chloride of lime." CALCIUM. 207 342. Calcii Hypophosphis. HypophospJiite of Calcium {Lime). Ca(PH 2 2 ) 2 . This salt is most conveniently prepared by heating two parts of Hydrate of Calcium (slacked lime) with 1 part of phosphorus and 10 parts of water, until phosphuretted hydrogen gas ceases to be evolved, then filtering the liquid to separate insoluble matter, concentrating the filtrate by evap- oration, refiltering, evaporating again until a pellicle appears on the surface ; then setting aside to crystallize or continuing the heat, and stirring to granulate. In conducting this pro- cess it is necessary to provide for the escape of the gas, which is inflammable, by means of a hood adjusted over the vessel in which the mixture is heated. The evaporation should also be at a low temperature, not over 185 F. Uses. — In pharmacy this salt is used for preparing other hypophosphites and hypophosphorous acid ; in syrups, etc. In medicine it is employed in wasting diseases, coughs, defective nutrition, nervous anemia, etc. The dose is from 5 to 30 grains, usually given in the form of syrup, solution or emulsion. 343. Calcii Phosphas Praecipitatus. Precipitated Phosphate of Calcium {Lime). Ca 3 (P0 4 ) 2 . Bone Ash, powdered 4 tr.ounces. Hydrochloric Acid, 8 tr.ounces. Water of Ammonia, q. s. or . . . .12 fl. ounces. Distilled Water, a sufficient quantity. Macerate tin- Hone- Ash in the hydrochloric acid, diluted with a pint of distilled water until it is dissolved, and filter the solu- tion. Add a pint of distilled water through the filter, and then gradually add water of ammonia until the liquid shows an alkaline reaction. Mix the magma (precipitate) with twice its bulk of boiling distilled water, and pour the- whole upon a 208 CALCIUM. calico strainer. Wash the precipitate on the strainer with boiling distilled water until the washings cease to give a cloud- iness with solution of nitrate of silver acidulated with nitric acid ; and, lastly, dry by gentle heat. Uses. — Precipitated phosphate of Calcium, or Phosphate of Lime as it is generally called, is used for preparing solutions of phosphates and lacto-phosphates compound, and many other preparations used in pharmacy ; also in making medi- cated waters. In medicine it is employed as an antacid, osseous, nutritive, etc. The dose is from 10 to 30 grains. 344. Calx. Lime — Oxide of Calcium. Lime is made by calcining or " burning" lime-stone, marble, or chalk, thus expelling the carbonic acid gas. It is an alka- line earth, much employed for building and other useful pur- poses, and in pharmacy is extensively used in making many galenicals. In medicine it is sometime employed as an eschar- otic, and its solution (lime-water) is extensively prescribed and used both internally and externally. 345. Calcii Hydras. Hydrate of Lime — Slacked Lime. This is so common a preparation that it scarcely needs a formula, but it may not be out of place to give the Br. official directions for making it : Lime, 2 pounds av. Distilled Water, 20 fl. ounces. Place the Lime in a metal pot, pour the water upon it, and when vapor ceases to be disengaged cover the pot with its lid and set it aside to cool. When cool, pass through a sieve and keep in well-stopped bottles excluded from the air. Slacked Lime is used to prepare Liquor Calcis, or Lime Water, and Syrupus Calcis, or Syrup of Lime. CALCIUM. 209 346. Calx Chlorata, U. S., Calx Chlorinata, Br. Chlorinated Lime — {Chloride of Lime). This preparation is made by exposing slacked lime to the action of chlorine so long as the gas is absorbed. It is exten- sively used for bleaching and disinfecting, and is familiarly known as Bleaching Powder. Freshly prepared Chloride of Lime contains from 30 to 35 per cent, of Chlorine, but loses most of it by age or exposure. In pharmacy it is used for making several preparations, and is much employed as a cheap deodorizer and disinfectant. Chlorinated Lime should not be mistaken for Chloride of Cal- cium, which is a true calcium salt. 347. Calcii Sulphurata. Sulphurated Lime — Sulphide of Calcium. The U. S. P. defines this as " a mixture consisting chiefly of Sulphide of Calcium (CaS) and Sulphate of Calcium (CaS0 4 ) in varying proportions, but containing not less than 36 per cent, of absolute Sulphide of Calcium." The Br. P. describes it as " a mixture containing not less than 50 per cent, of Sul- phide of Calcium." As the processes for making it vary considerably, and are not expedient, except for manufacturing chemists, they are not here repeated. Uses. — This substance is used as a depilatory, and some- times in ointments. It is also given internally for skin diseases and as an alterative, in doses of ^ to 1 grain. Other Calcium Salts. Besides the foregoing official salts of Calcium, several unoffi- cial salts are sometimes used : 348. Fluoride of Calcium— CaFj,. — This salt occurs native, and is known as Fluor-Spar. It may also be prepared by acting upon lime with hydrofluoric acid. 210 CARBONIUM — CARBON. 349. Iodate of Calcium — Ca2l0 3 .6H,0. — By gradually adding a filtered solution of chlorinated lime to an alcoholic solution of iodine, and when the solution is colorless, acidulating with a little hydrochloric acid, boiling, filter- ing, and crystallizing. 350. Iodide of Calcium — Cal 2 . — By dissolving slacked lime in hydriodic acid, until neutralized, then concentrating and crystallizing. This salt is con- siderably used as an alterative, in doses of }i to 2 grains. 351. Sulphides of Calcium. — With sulphur, Calcium forms several sul- phides, as follows : Sulphide of Calcium — CaS. — Made by exposing Sul- phate of Calcium at a high temperature to a current of hydrogen gas. Bisulphide of Calcium — CaS 3 . — By boiling slaked lime and sulphur, equal parts, in water until a solution is obtained, filtering, concentrating and crystal- lizing. Pentasulphide of Calcium — CaS 5 . — By using double the quantity of sulphur as for the former, and continuing the boiling longer. Oxysulphide of Calcium. — By mixing 1 part of sulphur with 3 parts of slaked lime and 5 parts of water, and boiling until a portion dropped upon a cold slab will solidify. 352. Sulphate of Calcium — CaS0 4 .2H 2 0. — This is found abundantly in nature, and is known as, gypsum. When calcined 2H 3 is driven off, and when ground this is known as calcined plaster, Plaster of Paris, or Dentists' plaster. 353. Sulphide of Calcium — CaS0 3 . — By mixing concentrated solutions of sulphide of sodium and chloride of calcium, and collecting, washing and drying the precipitate. This preparation has had a large sale formerly under the name Sulphite of Lime, as a preservative for cider. CARBONIUM — CARBON. Symbol, C ; Atomic weight, 12. Carbon is one of the most important and widely distributed elements. It exists in nature in a great variety of forms, differ- ing widely in appearance and characteristics. The diamond and graphite are familiar forms of crystallized carbon ; lamp- black and wood charcoal are forms of impure amorphous carbon. It is a constituent of all animal and vegetable sub- stances, and has therefore been called the " Organic element." It is present in all alkaloids and neutral principles of plants, and its compounds include the greater part of the substances most valuable in pharmacy and medicine. CARBOXIUM — CARBON. 211 354. Carbo Animalis. Animal Cliarcoal. Animal Charcoal is known commercially as ivory-black or bone-black, and is prepared in a large way by first boiling bones in water to free them from fat and adhering particles, and then subjecting them to destructive distillation in iron cylinders, by which process they are deprived of their volatile portions, as ammoniacal liquor, or bone spirit and tar, or bone oil, and become charred, consisting mainly of carbon and calcium salts. Uses. — Animal charcoal is extensively used for decolorizing substances by filtering them through it, especially for refining sugar, making petrolatum, etc. ; also for making blacking for shoes and as a pigment. For pharmaceutical use, purified animal charcoal should be used. 355. Carbo Animalis Purificatus. Purified Animal Charcoal. Animal Charcoal, .... 2 parts or 8 ounces av. Hydrochloric Acid, ... 3 parts or 10 fl. ounces. Water, a sufficient quantity. Pour the hydrochloric acid, previously mixed with 4 pints of water, upon the animal charcoal and digest the mixture on a water-bath for 24 hours, occasionally stirring (this is for the purpose of dissolving the calcium salts which are present); then pour off the supernatant liquid and digest the undissolved portion with 4 pints of water for two hours, transfer the mix- ture to a strainer, and when the liquid portion has run off, wash tile residue with water until the washings give no cloud with a solution of nitrate of silver; then dry the product and heat it to dull redness in a covered crucible. Uses. — Thus treated, the crude bone-black becomes pure Carbon, which may be used for delicate chemical or pharma- ceutical operations. It is chiefly used for filtering and decolor- izing solutions of alkaloids and line chemicals. 212 CARBONIUM — CARBON. 356. Carbo Ligni. Charcoal — Wood-Charcoal. This is prepared for commerce by charcoal-burners, who pile billets of wood in conical form, cover the pile with earth, ignite it from the bottom, and then close it from access of air, leaving the process to go on without consuming the wood, which is by the heat deprived of its oxygen, hydrogen, etc. leaving charcoal or carbon as the result of the operation. For pharmaceutical use, charcoal prepared from willow is preferred. Uses. — In pharmacy, powdered charcoal is used for filtering many substances that cannot be made clear by ordinary filter- ing processes. It is also used in tooth powders. In medicine it is given in doses of one or two drachms as an antiseptic, and absorbent especially in gastric derangements. On account of its absorbent qualities, it should be kept in tight tin cans or bottles. 357. Carboni Bisulphidum. Bisulphide of Carbon. CS 2 . This is a clear, colorless, very volatile and inflammable liquid, having sp. gr. 1.272. It is made by combining the vapor of sulphur with carbon, collecting the gaseous product by means of condensing tubes, agitating the liquid with mercury, and distilling it in contact with white wax. Crude Disulphide of Carbon has a very dis- agreeable odor, like rotten eggs, but this may be almost entirely removed by repeated rectification. It is never pre- pared except by manufacturing chemists, who have appropriate apparatus for making it. Uses. — Bisulphide of Carbon is a powerful solvent of fats, resins, rubber, etc., and is used in pharmacy chiefly for that purpose. Its vapor is sometimes used in the form of spray in surgical operations, but it is not administered internally. It is CARBONIUM — CARBON. 213 also a powerful antiseptic, and is used to preserve animal and vegetable substances. Other Carbon Compounds. Besides its combination with sulphur, which is official, carbon combines with chlorine in several proportions, with oxygen in two proportions, and with hydrogen in many proportions, forming a series of important radicals : 358. Chlorides of Carbon. — A Chloride of Carbon is obtained from its sesqui-chloride by subliming it repeatedly through a tube filled with frag- ments of glass heated to redness. It is a transparent aromatic liquid. Sesqui- chloride of Carbon — C 3 C1 6 — is obtained by exposing Dutch liquid with chlorine in a glass vessel to the direct rays of the sun, and renewing the chlorine as long as it is absorbed. The liquid is thus converted into a white crystalline volatile solid. Tetrachloride of Carbon, or Bichloride of Carbon, is made by a complicated process. It is a colorless liquid, sometimes used as an anaesthetic. Oxychloride of Carbon — COCl 3 — is a gas made by mixing equal volumes of carbonic oxide and chlorine and exposing them to the rays of the sun. 359. Hydrides of Carbon. — With hydrogen, carbon unites in many pro- portions, forming a series of radicals known as the hydro-carbon series, or alcohol radicals. Beginning with methane or marsh-gas, CH 4 , this series increases by CH 2 , forming the radicals ethyl or ethane, C 2 H r> , propyl or propane, C.,H S , butyl or tetrane, C 4 H 10 , amyl or pentane, C 5 H 13 . etc. In pharmacy these radicals are bases of very important preparations, which are extensively used. Carburetted Hydrogen is a term applied to two of the compounds of carbon and hydrogen, namely Light Carburetted Hydrogen, CH 4 , marsh-gas or tire-damp ; Heavy Carburetted Hydrogen, C 2 H 4 , olefiant gas or ethylene. 360. Oxides of Carbon. — With oxygen carbon forms at least two combi- nations, carbon oxide and carbon dioxide. 361. Oxide of Carbon — L'( ) — This is produced when carbon is burned in an insufficient supply of oxygen, or may be made by passing carbonic acid gas over charcoal heated to dull redness, and then washing the gas through milk of lime to remove carbonic acid. It burns in the air, uniting with . and being converted into carbon dioxide. 362. Dioxide of Carbon — CO g . Carbonic Anhydride, more commonlj called Carbonic .hid. This ;£ ounce av. Digest the Alkanet in the Almond Oil for some days, then filter or strain, add the Wax, melt and perfume while cooling with Otto of Roses, 30 drops, or other suitable perfuming oil a sufficient quantity. This makes a nice lip salve. Other formulas will be found among the Toilet Preparations. Of other Cerates that are sometimes called for or prescribed, many will be found among the ointments of corresponding names. A few not thus classi- fied are of sufficient importance to deserve mention here. 390. Ammoniacal Cerate. — Carbonate of Ammonium 1 drachm, Simple Cerate 1 ounce. Used as a counter-irritant in croup, etc. 391. Arsenical Cerate. — Arsenious Acid in fine powder 20 grains, Sim- ple Cerate 1 ounce. Applied to cancerous sores, etc. 392. Cacao Cerate. — Butter of Cacao, Oil of Sweet Almonds, and White Wax, each equal parts, melted together. For chaps, etc. 393. Chalk Cerate. — Chalk in fine powder 1 ounce, Simple Cerate 3 ounces, Almond Oil iyi, ounces. Mix. 394. Copaiba Cerate. — Add 1 ounce of Balsam Copaiba to 8 ounces of Spermaceti Cerate, previously melted. A stimulating application. 395. Marshall's Cerate. — Palm Oil 2 ounces, Calomel 2 ounces, Acetate of Lead in fine powder 1 ounce, Nitrate of Mercury Ointment 4 ounces; rub them together. This is applied to the eyes. 396. Pitch Cerate. — Yellow Wax 8 ounces, Suet 4 ounces, Burgundy Pitch 6 ounces. Melt them together. 397. Verdigris Cerate.— Wax and Resin each 5 ounces, Venice Turpen- tine 5 ounces, Linseed Oil 2 ounces, Verdigris 1 ounce. Melt and mix them together. This is sometimes called Green Cerate. Red Cerate is made by adding 1 drachm of Vermilion to 1 ounce of Cerate. CERIUM. Symbol, Cc ; Atomic weight, 140; Sp. gr. 6.62. Cerium is a metallic element found in the mineral cerite. It is of a chocolate-brown color, and is classed chemically, with aluminium, cadmium and /.inc. It unites with acids to form salt--, the oxalate only being official. CERIUM. CETACEUM — SPERMACETI. 398. Cerii Oxalas. Oxalate of Cerium. Ce 2 (C 2 4 ) 3 . 9 H 2 0. The powdered mineral cerite, which consists of silicates of several metals is treated with strong sulphuric acid or hydro- chloric acid, by the aid of heat, to separate the silica. Ammonia is then added to the filtered diluted solution, and the precipitated hydrates are again treated with acids to separate other metals. The Cerium compounds are then pre- cipitated by oxalic acid, the precipitate consisting of oxalates of Cerium, lanthanum and didymium, the latter metals are then separated with difficulty, leaving the Oxalate of Cerium. Uses. — This salt is considerably prescribed in the nausea and vomiting of pregnancy, in doses of 2 to 10 grains. Other Salts of Cerium. The Oxalate of Cerium is the only Cerium salt of import- ance in pharmacy, the following, however, may be mentioned : 399. Chloride of Cerium — CeCl 3 . — Made by burning Cerium in chlorine gas and collecting the mass. 400. Nitrate of Cerium — CeN0 3 2H 3 0. — This may be made by dis- solving ceroso-ceric oxide by nitric acid in the presence of alcohol. 401. Oxides of Cerium. — When Cerium is burned in the atmosphere, or with oxygen it forms oxides, as follows, under varying conditions : Cerous Oxide Ce 2 3 , Ceric Oxide CeO \. By igniting Oxalate of Cerium in an open vessel Ceroso-Ceric Oxide Ce 3 4 is formed. 402. Sulphate of Cerium — Ce 2 (S0 4 ) 3 . — By dissolving Oxide of Cerium in sulphuric acid, evaporating and crystallizing. 403. CETACEUM — SPERMACETI. Spermaceti is a " peculiar concrete, fatty substance," obtained from the oleaginous matter found in the head of the sperm whale, PJiyscter macrocephalus. The oily matter from which Spermaceti is obtained is found in a large cavity CATACEUM — SPERMACETI. CHARTVE — PAPERS. 227 in the upper jaw, and is dipped out soon after the animal is dead, as an oily liquid which congeals into a yellow mass. This is drained in suitable bags, and then pressed with great force, to remove the liquid olein, leaving the solid cetin in the bags. This is then purified by melting in water, straining, boiling with weak solution of potash, then washing with water, and is finally allowed to congeal into a white crystalline mass, somewhat resembling wax. Its low, melting point, 50°C. (i22°F.), combined with its solidity when cold, makes it a valuable addition to many ointments and cerates, giving them a firm consistence, but allowing them to be readily worked or softened. Uses. — Spermaceti is employed in pharmacy to give con- sistence to ointments, etc., and as an ingredient in several toilet preparations, Cranes, etc. It is also used to give a gloss to starch. In medicine it is frequently given to allay internal irritation. It may be powdered by fusing it and rubbing it in a mortar until cold. Mixed with three times its weight of sugar it is the Saccharated Spermaceti considerable pre- scribed in France and Germany. CHARTS — PAPERS. In pharmacy a few medicinally prepared papers for various purposes are known, of which three are official in the U. S. P., and two in the new Br. P. They may readily be prepared by druggists. The following are the official papers : 404. Charta Cantharides, U. S. CantJiarides Paper. White Wax, 4 ounces av. Spermaceti, ij4 ounces av. Olive Oil 2 fl. ounces. Canada Turpentine (Balsam Fir), l / 2 ounce av. Cantharides in No. 40 powder, . % ounce av. Water, 5 fl. ounces. Mix all the substances in a tinned vessel and boil gently for two hours, constantly stirring; strain through a woolen 228 CHARTS — PAPERS. strainer without expressing, and-, by means of a water-bath, keep the mixture in a liquid state in a shallow, flat-bottomed vessel with an extended surface. Coat strips of sized paper with the melted plaster, on one side only, by passing them successively over the surface of the liquid. When dry cut the stripes into rectangular pieces. Uses. — This is used for producing blisters, and is first to be rubbed over with a little oil of turpentine or alcohol and then applied. 405. Charta Epispastica. Br. Blistering Paper. White Wax 4 ounces av. Spermaceti 1^ ounces av. Olive Oil 2 fl. ounces. Resin, ^ ounce av. Canada Balsam, % ounce av. Cantharides in powder, .... 1 ounce av. Distilled Water, 6 fl. ounces. The directions for making are essentially the same as the preceding. It contains double the quantity of cantharides. 406. Charta Potassii Nitratis, U. S. Nitrate of Potassium Paper. Nitrate of Potassium, 2 ounces. Distilled Water 8 ounces. " Dissolve the Nitrate of Potassium in the Distilled Water; immerse stripes of white unsized paper in the solution and dry them." Coarse straw paper is better than white paper for this purpose. Uses. — This is chiefly used for asthma, or to sprinkle asthmatic remedies upon and ignite, that their smoke or vapor may be inhaled. CHART.-E — PAPERS. 229 407. Charta Sinapis. Mustard Paper. The following is the U. S. 1S80 formula, adapted to water- bath percolation : Black Mustard, in No. 60 powder, ) ■Benzin, f each a sufficient Solution of Gutta-Percha, . . \ q uantlt y- Pack the Mustard firmly in the water-bath percolator and gradually pour Benzin upon it ; pour hot water in the water- bath surrounding the percolator, and percolate with the Benzin until the percolate ceases to produce a permanent greasy stain upon blotting paper. (This operation is for the pur- pose of removing the fixed oil from the Mustard.) Remove the powder from the percolator and dry it by exposure to the air. Then mix with it sufficient Solution of Gutta-Percha to give it a semi-liquid consistence, and apply with a brush to one side of heavy, well-sized paper, and allow to dry. Each square inch of the paper should contain about 6 grains of Mustard. The Br. formula is similar to the U. S., 1870. Mustard in powder, I ounce av. Solution of Gutta-Percha, about, ... 2 fl. ounces. Mix the Mustard with the Gutta-Percha solution so as to form a semi-fluid mixture, and having poured this into a shallow-vessel pass strips of cartridge-paper over its surface, so that one side of the paper shall receive a thin coating of the mixture. Uses. — Mustard Paper is much used as a counter-irritant in neuralgia and many other diseases. Before applying it should first be immersed in warm water for about 15 seconds. Other Papers. Besides the foregoing official papers which are employed in medicine, others are known and sometimes used for applica- tions and other purposes. A variety of papers are also made for various purposes, useful in pharmacy as test papers, parchment paper for dialysing, filtering paper, carbon paper 230 CHARTVE — PAPERS. for duplicating, etc. The more important papers are as follows : 408. Antiasthmatic Paper.— Unsized gray filtering paper, 6 ounces ; nitrate of potassium in fine powder, 3 ounces ; belladonna, stramonium, digitalis, lobelia, and water-fennel, all in fine powder, % ounce each ; myrrh and olibanum in powder, y 2 ounce each. Tear up the filtering paper, and soak in water until soft ; press out the water and beat the mass into a pulp, with which incorporate the powders ; put into suitable moulds and dry. This may be moulded similar to pastils, which see. 409. Antirheumatic Paper. — Euphorbium, 1 ounce ; cantharides, y z ounce ; alcohol, 5 ounces. Macerate for one week, filter and add resin, 2 ounces ; turpentine (gum), \% ounces. This makes a varnish, which is to be brushed over thin paper. 410. Gout Paper— Papier Fayard. — Euphorbium, 1 part; cantharides, 2 parts, both in fine powder ; are digested with alcohol, 8 parts ; ether, 3 parts, in a stoppered bottle for a week, with frequent agitation. The tincture is then strained or filtered, one part of Venice turpentine added, and thin, white paper dipped in the solution. This is considerably used as a counter- irritant for rheumatism, neuralgia, gout, etc. 411. Copying Paper. — Thin, strong, soft paper is prepared in various ways for duplicating writing with a pencil or style. Black is the color most commonly used, but other colors are employed for tracing patterns, etc. The black copying paper is known in the market as carbon paper, and is made by mixing lampblack with lard, palm oil, or, preferably, with petrolatum, and rubbing the paper thoroughly over with the mixture, then, after standing a few hours, rubbing off the superfluous grease with a flannel rag. The operation should be conducted in a warm room, so that the pigment will be absorbed by the paper, and when rubbed off it will retain only enough for the purpose of copying, and not crock the paper being used for the writing. By placing alternate sheets of paper and copying paper, several duplicates may be obtained with one writing. This is called " Manifold " writing. Other colors may be made in the same manner, by using other pigments, as vermilion or other reds for red; umber or other browns for brown; chrome green for greeti ; chrome yellow for yellow, etc. For tracing patterns, heavier paper is generally used. 412. Fly Paper.— Two kinds of papers for destroying flies are found on the market — the poison and the sticky fly papers. They are generally pro- prietary, but can readily be made by druggists, and afford a large profit. Poison Fly Paper. — This is prepared by dipping coarse paper, made from woolen rags, into some kind of poison solution, and drying by hanging on lines. The poison solution may be made as follows : White Arsenic (Arsenious Acid) 4 pounds av. Concentrated Lye 1 pound av. Water, 10 gallons. CHARTS — PAPERS. 231 Dissolve the Concentrated Lye or caustic soda in the water and boil the solution, gradually adding the Arsenic, and continuing to boil until it is dis- solved, then while still warm dip the paper in it, and hang on lines to dry. The paper thus prepared is cut into small sheets, put in saucers or plates, and water poured upon them, which dissolves the Arsenic. The flies drink of the water and die. Other substances may be used for making the solution, as tartar emetic, corrosive sublimate, etc.; but the Arsenic is probably the best and cheapest. Sticky Fly Paper. — This is a very popular paper for destroying flies, because it holds them, and they do not drop around and into things, as is the case when poison paper is used. It may be made in a variety of ways ; but the best and cheapest is made as follows : Resin 2 pounds. Cotton Seed or " Salad " Oil, about, 8 ounces. Melt the Resin, and add to it half a pint of the oil. Owing to the differ- ence in Resin more or less oil may be required ; the object is to have it, when spread upon paper, sticky enough to hold the flies, yet not stiff enough so but when the paper is folded it may readily be pulled apart without tearing. A little may be spread upon paper and tested, then more oil or Resin may be added if necessary. This is spread, while warm, with a brush, spatula, muller, or other convenient utensil, upon sheets of firm, sized, white, or manilla paper, leaving a margin unspread, the paper is then folded together, and pulled apart when wanted for use. 413. Oiled Paper. — This is used in pharmacy for doing up packages of chemicals or other substances which are affected by moisture or air ; also for capping bottles, jars, etc. It may be made by brushing sheets of paper of any desired thickness with boiled linseed oil, and drying them on a line. Oiled card board is used in copying-books for copying letters. 414. Parchment Paper, — Used in pharmacy for dialysing and for cover- ing jars, capping bottle tops, etc. It is prepared from strong, white, unsized paper by dipping it for half a minute in strong sulphuric acid, diluted with a quarter of its measure of water, and then, after standing a few moments, into water containing a small quantity of ammonia. 415. Test Papers. — Various kinds of test papers are used in pharmacy — the most used and best known being blue and red litmus paper, for detecting the presence of acids or alkalies. Blue Litmits Paper is made by dipping strips of filter-paper into an infu- sion of Litmus, made as follows : Triturate 1 ounce of Litmus in a mortar with 4 ounces of boiling water; pour off the liquid and add more boiling water in two or three portions until half a pint of the solution altogether is obtained. When cold, filter the solution and divide the filtrate into two equal portions ; into one of these add with a glass rod a very small quantity of 232 CHART.E — PAPERS. CHEMICALS. sulphuric acid until it begins to be very slightly red ; then mix the two por- tions again and dip the paper in them as directed. Blue litmus paper is a delicate test for acids, which turn it red. Red Litmus Papa-. — To the solution of blue litmus prepared as above add sulphuric acid gradually by dipping a glass rod in it and then in the solution of litmus until it has a distinctly red color. Dip strips of filtering paper into this solution and dry. Red litmus paper is a delicate test for alkalies, which turn it blue. Tumeric Paper. — This is a yellow paper, sometimes directed to be used as a test for alkalies, which turn it brown. It is also turned brown by boric acid and soluble borates. It is made by boiling 2 ounces of tumeric in one pint of water, and dipping strips of paper in the decoction. 416. Tracing Paper.— For tracing drawings, designs, patterns, etc., thin, unsized white paper is made semi-transparent by applying to it with a brush a varnish made with equal parts of Canada Balsam and Oil of Tur- pentine, and drying by hanging on a line. It may also be made by applying a mixture of equal parts of Cotton Seed Oil and Oil of Turpentine ; but the excess of oil must be absorbed by rubbing it over as soon as applied with flour or starch. The latter is more flexible than the former, but not so transparent. 417. Waxed or Paraffin Paper. — This may be made in a small way by dipping sheets of thin paper into a vessel of melted paraffin, and afterwards ironing them over with a hot flat-iron. Commercially, it is made by passing paper through rollers heated by steam and fed with melted paraffin. This paper is useful in pharmacy for covering over ointments, etc., and wrapping around packages of camphor ice, cosmetics, etc., to prevent them greasing the packages in which they are contained. It is much used by grocers to cover packages of lard, butter, or other greasy substances. Besides the foregoing " papers," which may readily be made by drug- gists, Filtering Paper is an essential in pharmacy. It is made only by manufacturers who make a business of it. The best Swedish filtering paper is made of pure flax fibres, very finely crushed and broken ; the white English papers have some cotton mixed with the flax ; while the common gray circu- lar papers of French, Dutch, and English manufacture, contain consider- able wool, jute, and esparto grass, making them more porous and rapid filters than the other varieties, but not suited for fine chemical work. CHEMICALS. As known in pharmacy, "Chemicals" are products of the laboratory, or natural substances, having definite molecular CHEMICALS. CHLORAL. 233 composition and characteristics by which they may be known and recognized. They differ from " Pharmaceuticals," in thus having a definite chemical composition, while the latter are merely mixtures or compounds of substances without definite chemical proportion. Chemicals, as they are thus understood, include the metals and non-metals, the acids, the alkalies, and the alkaloids, together with the salts, which are produced by combining them. They are mostly made by manufacturing chemists, although many of them may readily be prepared by druggists. In this work the principal chemicals are noticed under the classes to which they properly belong, as AciDA, ALKALOIDES, etc., or the elementary substances which form the bases of the compounds, as Arsenicum, Bismuthum, etc. For more complete description and classification of chem- icals, the reader is referred to FENNER'S Practical Chemis- try, or other standard chemical text-books. CHLORAL. C 2 HC1 3 0. A peculiar oily liquid, obtained by the action of Chlorine on alcohol, first discovered and named by Liebig, is chemi- cally known as Chloral. Some confusion is liable to occur, because the 1880 U. S. P. has designated the substance known commercially as Hydrate of Chloral simply by the name " Chloral." The following describes the process of making both Chloral and Hydrate of Chl&ral : 418. Chloral, U. S., Chloral Hydras, Br. Hydrate of Chloral. C.HCI3O.H0O. Chloral and Hydrate of Chloral are prepared by manufac- turing chemists, by passing dry chlorine gas for several weeks 234 CHLORAL. into absolute alcohol contained in a suitable vessel, until it becomes a thick oily liquid of sp. gr. 1.502. At first the alcohol is cooled by surrounding the vessel with ice to prevent explosion, but when no more will be absorbed toward the end of the operation, it is heated to nearly the boiling point, 6o°C. (i40°F.) The liquid thus obtained is Chloral. To purify it, it is agitated with four times its bulk of concentrated sulphuric acid for several hours at a temperature of 6o°C. (i40°F.), most of the hydrochloric acid escaping. The Chloral then separates as an oily layer on the top, and is further purified by distilling over calcium carbonate. This is pure Anhydrous Chloral. To make Hydrate of Chloral, it is mixed in glass vessels with the required quantity of water, and allowed to solidify into a cake, or " crust." This may be fur- ther purified by dissolving it in chloroform, benzin, or ethyliden chloride, and crystallizing, and it is mostly used at present in this form. Chemically, Chloral is an aldehyd derivative, known as trichloraldehyd. Uses. — Chloral is a hypnotic, used in delirium, nervous irritability, etc. The dose is from 10 to 30 grains, usually given in flavored syrup as syrup of ginger or orange. 419. Camphor-Chloral. When Hydrate of Chloral and Camphor in nearly equal quantities are rubbed together in a mortar, the two solids unite and form a syrupy liquid, which is often employed for tooth- ache, facial neuralgia, and other painful affections. It may be made as follows : Camphor, 5 parts or drachms. Hydrate of Chloral, 4 parts or drachms. Rub the Camphor, by the aid of a few drops of alcohol, to a powder, and add the Chloral, rubbing them together until they become liquid. This may be diluted if desired by mixing it with alcohol and glycerin equal parts. When thus prepared it may be used as an anodyne application or liniment, or may be given internally. CHLORINE. 235 CHLORINE. Symbol, CI.; Atomic weight, 35.4. Chlorine is a gaseous element of greenish-yellow color and suffocating odor. Its specific gravity is 2.45. It was discovered by Scheele in 1774, and was, later on, classed with the elements, and named, from its color, by Davy. Chlorine combines with every other element except fluorine, and is therefore of great interest and importance. It possesses wonderful bleaching properties, and is largely used in the arts for this purpose. It is also a powerful disinfectant. Its com- pounds with the alkali metals are of great industrial value and application, and its salts form a large class of chemicals useful in pharmacy and medicine. It combines with other elements forming chlorides, and in combination with oxacids unites with bases, forming chlorates and perchlorates. Chlorine may be obtained by heating hydrochloric acid with peroxide of manganese in a flask and collecting the gas ; but is prepared commercially in apparatus specially constructed for the purpose. The only preparation in which Chlorine is exhibited in a free state is in Chlorine water, which was formerly official in the U. S. P., and is now official in the Br. P. under the title 420. Liquor-Chlori, or Aqua-Chlori. Solution of Chlorine, Chlorine Water. The British formula is as follows : Hydrochloric Acid, 6 fl. ounces. Black Oxide of Manganese, 1 ounce av. Distilled Water, 34 fl. ounces. Put the Oxide of Manganese into a gas bottle, and having poured upon it the hydrochloric acid diluted with two ounces of the water, apply heat gently, and by suitable tubes cause the gas developed to pass through two ounces of the water 23C> CHLORINE. placed in an intermediate small phial, and thence to the bot- tom of a three-pint (6o-ounce) bottle, containing the remainder of the water, etc. When the gas has all been generated, shake the bottle that the gas may be absorbed by the water. Uses. — Chlorine Water is employed as an antiseptic wash and gargle, especially for diphtheria and ulcerated sore throat. It is also given internally in fevers and other septic disorders, in doses of from 10 to 30 minims, largely diluted with water. Acids of Chlorine. 421. Hypochlorous Acids — HCIO— may be made by agitating chlorine water with red precipitate, and distilling the liquid, to separate the solution of the gas from the Chloride of Mercury, which results from the reaction. 422. Chlorous Acid — HC10 2 . — Made by heating together in a glass flask in a water-bath Chlorate of Potassium 4 parts, Arsenic 3 parts, Nitric Acid 1 2 parts, Water 4 parts. The gas generated by the operation is con- ducted by a bent tube into a receiver, containing water. It is a great bleach- ing and oxidizing agent. 423. Chloric Acid — HC10 3 . — This may be made by decomposing Chlo- rate of Barium with an equivalent quantity of pure diluted sulphuric acid, and evaporating the liquid poured off from the precipitate, in vacuo, over strong sulphuric acid. Although this is the acid basis of the Chlorates, it is seldom used in pharmacy. 424. Hydrochloric Acid — HC1. — This is the only compound of hydro- gen and Chlorine known. It was formerly called Muriatic Acid. It is obtained chiefly as a by-product in the manufacture of soda-ash from com- mon salt by heating to a high temperature with sulphuric acid, by which process sulphate of sodium is formed, and hydrochloric acid liberated in the form of gas ; this is then purified and dissolved in water by various methods, forming the Hydrochloric Acid of Commerce, which contains 31.9 per cent, of the gaseous acid. It is frequently called for as Spirit of Salt or Oil of Salt. It is the acid basis of the Chlorides, and is much used in pharmacy and the arts. See page 60. 425. Perchloric Acid — HC10 4 . — By distilling pure dry Perchlorate of Potassium with four times its weight of boiled, concentrated sulphuric acid and collecting the distillate. Besides the combinations of hydrogen and oxygen with chlorine, it forms compounds with someother acids, as Chlorochromic Acid, CrOCl, Chloro- carbonic Acid, COCl 2 , etc., and with elements as Chloride of Bromine, etc. CHLOROFORUM — CHLOROFORM. CHOCOLATA. 237 426. CHLOROFORUM — CHLOROFORM. CHCI3. Chloroform is a derivative of aldehyd, known chemically as trichlormethane. Several methods of preparing it are employed by manufacturing chemists, the most familiar being by the action of chlorinated lime on alcohol. A recent process is now employed, commercially, by which wood or sawdust is decomposed at a high temperature, and chloroform prepared from the crude acetates obtained at a much lower cost of pro- duction. The uses of Chloroform as an anaesthetic, narcotic and seda- tive are well known. It is employed internally as a sedative and narcotic, in doses of from 1 to 10 minims, largely diluted ; and externally as a counter-irritant and sedative in liniments, and applications for neuralgia, pain, etc. The U. S. P. recognizes two preparations of Chloroform, namely, Purified Chloroform and Commercial Chloroform. The Br. P. mentions only Chloroform, which corresponds with the U. S. Purified Chloroform. Commercial Chloroform should only be used externally. Purified Chloroform may be used externally, internally, or by inhalation, and is now quite gen- erally used by druggists for all purposes. As the processes for making Chloroform are somewhat com- plicated, and it is seldom made except by manufacturing chemists, they are not here repeated. Chloroform should have a specific gravity of about 1.490. It is soluble in about 200 parts of water, and in all proportions in ether and alcohol. It is not inflammable like ether. Prepa- rations containing Chloroform will be found under their appro- priate headings. 427. CHOCOLATA. Chocolate and Cocoa. Chocolate is prepared from the roasted seeds of Tkeobroma Cacao, deprived of their husks or "shell." Its manufacture in 238 CHOCOLATA. CHROMIUM. this country, although confined to only a few establishments, constitutes an important industry. To prepare Chocolate, the seeds, which are somewhat like small acorns, are roasted, then decorticated, or deprived of their covering or husks. The kernel is then ground in a mill, and made into a paste with heated metal rollers. It is then run into cakes. Chocolate, as thus prepared, contains consid- erable fatty matter, known as Oleum Theobrojiup, or Butter of Cacao. By mixing it with warm water, most of the oil rises to the top and is removed. The precipitate is collected, dried, and variously prepared, and is known on the market as COCOA. Chocolate and Cocoa are extensively used as nutritive drinks, for which they are more esteemed than tea and coffee. In confectionery vast quantities are used, chocolate confec- tionery being the universal favorite. In pharmacy Chocolate is frequently used in confections, for covering the taste of dis- agreeable medicines, and sometimes in making simple elixir to which it gives an agreeable flavor. It is extensively used, made into a syrup for the soda fountain. A variety of proprietary tablets, containing Chocolate as a base, have formerly been put upon the market, but as they are liable to become wormy or spoil, they have mostly been with- drawn. It is quite a common error to suppose that Chocolate and Cocoa are prepared from the well-known Cocoanut, the fruit of Cocus Nucifera, instead of the small acorn-like nuts or fruit of TJicobroma Cacao. CHROMIUM. Symbol, Cr. ; Atomic weight, 52.4. The element Chromium is a very hard, brittle, grayish-white metal. It was discovered by Vauquelin in 1797, and is obtained by igniting its oxide with charcoal at an intense heat. It occurs in nature in the form of ore combined with iron (chrome-iron ore) with lead and some other metals. Some of its salts are extensively used in dyeing, and two or CHROMIUM. 239 three of them in pharmacy and medicine. Chromic Acid or Anhydride and Bichromate of Potassium are the only prepa- rations of Chromium, which are used to any extent in medicine. The latter is noticed with the potassium salts. 428. Acidum Chromicum. Chromic Anhydride — Chromic Acid. C1-O3. With oxygen Chromium forms five compounds, namely, Chromous oxide, CrO, Chromium dioxide, CrO s , Chromium trioxide, Cr0 3 , Chromic oxide, Cr 2 3 , trichromic tetroxide, Cr 3 4 . The Trioxide of Chromium is the official chromic anhydride, or, as it is more commonly known, Chromic Acid. It is pre- pared according to the 1885 Br. P. as follows: Bichromate of Potassium, .... 30 ounces av. Sulphuric Acid (Imp. measure), . . 57 fl. ounces. Distilled Water, a sufficiency. Dissolve the Bichromate of Potassium in a mixture of 50 fl. ounces of water and 42 fl. ounces of the acid, set aside for 12 hours, and decant the liquor from the crystals of acid sulphate of potassium that have separated. Heat the liquor to about 185 F. (85 C), and add the remainder of the acid and water sufficient to just redissolve any crystals of chromic acid that may have formed. Allow to cool, collect and drain the crystals, and dry them on porous tiles at a tem- perature not exceeding ioo° F. in an air-bath. From the mother liquor more crystals may be obtained on evaporation. Uses. — Chromic Acid is a caustic and antiseptic, and is used for removing warts and other morbid growths. ■ It is not given internally. Some other Chromium Compounds arc known and sometimes used, as Bromide 0/ Chromium, Cr 2 Br , Dicidoridc of Chromium, CrCl 2 , Fluoride of Chromium, Cr 2 Fl , Iodide of Chromium, Crl r ,, Sulphate of Chromium, Cr 2 (S0 4 ) 3 , but they are usually furnished by chemists when wanted. 240 COBALTUM — COBALT. COLLODIA — COLLODIONS. COBALTUM — COBALT. Symbol, Co; Atomic weight, 58.9; sp. gr. 8.5. An elementary metal, classed chemically with nickel and tin, and usually found in nickel and arsenical ores. It is a tough, brittle, white metal when pure ; but the " Cobalt " which is sold in the stores as Flystojie is a native ore, contain- ing arsenic, CoAs 3 , and owes its value as a fly poison to the arsenic it contains. The black Oxide of Cobalt is much employed in the arts, especially as a basis of fine pigments, as its salts produce rich colors. The acetate, chloride, nitrate and sulphate of Cobalt are used for making sympathetic inks, which are invisi- ble on the paper, but may be developed by moisture, heat, etc. Barometer Paper is made by dipping white paper in a soluticn of Chloride of Cobalt. When dry the color is blue, but increased moisture in the atmosphere changes the color to pink. The Salts of Cobalt are not employed in medicine, and are seldom used in pharmacy, except as above noted. They may be made in a general way by dissolving the oxide or carbonate of Cobalt in acids, and crystallizing or precipitating. COLLODIA — COLLODIONS. Collodions are liquid preparations made by dissolving pyroxylin or gun-cotton in a mixture of ether and alcohol, and adding other substances if desired. Their value consists chiefly in forming a coating upon the surface to which they are applied, which is utilized in the arts for various purposes, and in medicine for the application of medicinal substances, or the protection of the parts to which they are applied. The volatile liquids which are contained in Collodions rapidly COLLODIA — COLLODIONS. 241 evaporate when exposed to the air or applied to a surface, leaving a thin flexible covering or skin. The following are the official Collodions ; 429. Collodium. Collodion. Pyroxylin, or Gun-Cotton, .... y 2 ounce av. Stronger Ether 11^3 fl. ounces. Alcohol 2,7/q fl. ounces. Add the Alcohol to the Pyroxylin in a bottle and let stand for 15 minutes, then add the Ether, and shake the mixture occasionally for several days until the Pyroxylin is dissolved, set aside, and when all sediment has subsided decant the clear portion and keep in tightly stopped bottles away from light or fire. This is substantially the U. S. 1880 formula. The Br. for- mula is Pyroxylin ]/ 2 ounce, Ether 18 fl. ounces, Rectified Spirit 6 fl. ounces, making a preparation containing only about two thirds as much gun-cotton as the former. Uses.— In the arts Collodion has been extensively employed in photography. In pharmacy, it is used as a basis for making several preparations, and in surgery, it is considerably used as a dressing for wounds, bruises, etc., forming a false mem- brane or skin over the surface. It is an ingredient of most of the popular corn cures, chiefly on account of its conveni- ence of application. 430. Collodium cum Cantharide, U. S. Collodion with Cantharides^ Cantharidal Collodion. The U. S. P., [880, directs this to be made by percolating 60 parts of powdered Cantharides with commercial Chloroform until 250 pails of tincture are obtained, then to recover by distillation 200 parts of the Chloroform, evaporate the residue to 15 parts, and dissolve in 85 parts of flexible collodion to make 1 00 parts. 242 COLLODIA — COLLODIONS. The following formula is essentially the same, and is to be preferred, as it makes a stronger and better preparation : MADE BY WATER-BATH PERCOLATION. Cantharides (in fine powder). ... 8 ounces av. Pyroxylin, ]/ 2 ounce av. Canada Turpentine (Balsam Fir), . 320 grains. Castor Oil, 160 grains. Stronger Ether, 1 15/ 8 fl. ounces. Alcohol, . . . 3^-8 fl. ounces. Commercial Chloroform, a sufficient quantity. Pack the Cantharides firmly in the water-bath percolator, and pour upon it a pint of Chloroform, adjusting the cover tightly on the percolator. Pour water heated to about 150 degrees in the water-bath which surrounds the percolator, and keep at a moderate heat for half an hour; then remove from the fire and begin to percolate, adding Chloroform to the drug in the percolator, and continuing the percolation until the Cantharides is exhausted, or until about 20 fl. ounces have passed. Distill off the Chloroform until only 2 ounces of the extract remains. When cool, add to this extract the other ingredients which have previously been made into Flexible Collodion, by mixing them together, as directed for making Collodion and Flexible Collodion, and, after standing without agitation for 48 hours, pour off from any sediment that may have subsided. The Chloroform remaining in the drug after percolation may be recovered by adjusting the still top and distilling as directed. The corresponding British preparation is as follows : COLLODIUM VESICANS. Blistering Collodion. Blistering Liquid (Tmp. measure), . . 20 fl. ounces. Pyroxylin, 1 ounce av. Add the Pyroxylin to the liquid in a stoppered bottle, and shake them together until the former is dissolved. The COLLODIA — COLLODIONS. 243 blistering liquid directed to be used is the Liquor Epispasticus of the Br. P.. made from Cantharides and acetic ether. Uses. — Cantharidal Collodion is only used externally for blistering. It is best applied to the parts with a camel's-hair pencil. 431. Collodium Flexile. Flexible Collodion. Collodion 92 parts or 1 ounce av. Canada Turpentine, ... 5 parts or 24 grains. Castor Oil 3 parts or 14 grains. Mix. As its name indicates, this is elastic or flexible. 432. Collodium Stypticum. Styptic Collodion — Styptic Colloid. Tannic Acid, 4 parts or 160 grains. Alcohol, 1 part or 52 minims. Stronger Ether 4 parts or 220 minims. Collodion 55 parts or 1 1° A- ounces. Put the Tannic Acid in a bottle, add the Alcohol, Ether and Collodion, and agitate until dissolved. Uses. — As its name indicates, this is used as an astringent and styptic. Tin- following unofficial Collodions are sometimes called for: 433. Antiseptic, Styptic Collodion. Tannic Acid 120 grains. Benzoic Acid 120 grains. Carbolic Acid 240 grains. Collodion, 6 11. ounces. Mix and dissolve. This is sometimes called Hemostatic Collodion. 434. Iodinal Collodion. Iodine 120 grains. Canada Turpentine 2 ll. drachms. ( lollodion ^ fl .ounces. 244 O M.I.i )DI A — COLLODIONS. COLORES — COLORS. Or Iodine, 15 grains. Flexible Collodion i flounce. The former formula was originally published by J. T. Shinn. It is used as an absorbent application. 435. Iodoform Collodion. Iodoform 30 grains. Balsam of Peru 30 grains. Green Soap 3° grains. Flexible Collodion, sufficient quantity to make 4.80 grains. Mix. An antiseptic dressing for ulcers, sores, etc. 436. Liebig's Corn Collodion. German Com Ciire. The following formula has been extensively published and used as a corn remedy, its chief advantage being its convenience of application : Salicylic Acid 10 grains. Extract of Indian Hemp, 60 grains. Collodion, 10 fl. drachms. Mix and dissolve. 437. Styptic Colloid. Chloride of Iron (the Salt) 60 grains. Collodion, ' I fl. ounce. Dissolve the Iron Salt in the Collodion. This is an excellent styptic for checking the flow of blood, and for erysipelas, etc. Besides the foregoing Collodions, there are a great variety which apply particularly to photography, the formulae for which appear in books and journals upon that subject. Some other medicinal Collodions are also made : such as Aconite Collodion, Belladonna Collodion, Morphine Collodion, etc., but they are prepared by mixing alcoholic fluid extracts of the drugs with Collodion, and do not require special formulas. COLORES -COLORS. In pharmacy a variety of preparations are made for coloring various medicinal and toilet preparations, juices, solutions, syrups, extracts, powders, etc. They are very properly divided COLORES — COLORS. 245 into several classes, which will be considered in the order of their importance in pharmacy. Many of the substances from which they are made will be noticed under other headings, as Anilina, Tinctoria, etc. Coloring Liquids. These are designed for coloring medicinal preparations, solu- tions, juices, syrups, extracts, spirits, liquors, cordials, elixirs, and all liquids in which it is necessary to use a harmless color- ing ingredient. They must, as a rule, make clear, transparent preparations when combined with aqueous solutions, or with spirits containing 50 per cent, of alcohol. 438. Caramel. Solution of Caramel, Burnt Sugar Coloring. (Brown.) Sugar, any convenient quantity. Water, a sufficient quantity. Put the Sugar (without water) into an iron kettle of several times the capacity required for it, heat it to 410 to 430 F. as long as it gives off any vapor, and until it is changed to a black, viscid mass, stirring it occasionally during the operation, then cool, and while cooling add hot water in the proportion of one pint for each pound of the sugar used, let stand to dissolve, strain the solution, and concentrate it by evaporation to a syrupy consistence, or until it measures a pint for each pound of sugar used. As ordinarily made, no precaution is taken to regulate the degree of heat, and for that reason a portion is converted into charcoal, which is insoluble. In small operations this is unini portant, but in manufacturing establishments the heat is regu- lated by an oil or sand-bath, or other means, to avoid this difficulty. Uses. -Caramel is extensively used for coloring liquors, bottled beverages, and in soda-water. syrups, etc. In pharmacy it is employed for coloring syrups, solutions, elixirs, wines, and other liquids, which are required t<> have an artificial brown 240 COLORES — COLORS. coloring. A reddish-brown is made by mixing caramel with red coloring. Preparations containing more than 50 per cent, of alcohol precipitate this coloring, and it may be obtained pure in the form of a mass or powder by pouring it into strong alcohol, and afterwards washing the precipitate with alcohol. 439. Carmine Coloring. Solution of Carmine. (Red.) Carmine, No. 40, 120 grains. Carbonate of Potassium (Salts of Tartar), 60 grains. Glycerin 2 fl. ounces. Water of Ammonia, x / 2 fl. ounce. Water, . . - 5 fl. ounces. Rub the Carmine with the Salts of Tartar to a fine powder, and then with the Glycerin, Water of Ammonia, and lastly with the Water, added in successive portions to rinse out the mortar. This is a strong red coloring, easily made, and will keep permanently. Uses. — This solution may be used for coloring all neutral elixirs, solutions, tinctures, syrups, etc., which do not contain a large percentage of alcohol. It is precipitated by acids, and cannot therefore be employed for coloring acid syrups, etc. It makes a fine Red ox Carmine Ink, and may be perfumed by diluting with an equal quantity of Orange Flower or Rose Water, and used as u Liquid Ronge." It may be used for giving a " flesh" tint to liquid face cosmetics, and may be mixed with face powders to give them the same. 440. Cochineal Red. Cochineal, 1 pound av. Carbonate of Sodium (Sal Soda), . . 1 ounce av. Alcohol, 1 pint. Water, sufficient to make 2 pints. Grind the Cochineal to a coarse powder, mix the alcohol with one pint of Water, and dissolve the Sal Soda in the mix- COLORES — COLORS. 247 ture, moisten the powder with the liquid, put in a water-bath percolator, pour upon it the remainder of the liquid, allow to stand 24 hours, heat moderately for one hour, then percolate, adding water to the drug after the liquid has disappeared from the surface, and continuing the percolation until 1^ pints of the percolate have passed, which reserve, continue the perco- lation with water until a pint more has passed, which evapo- rate to 4 fl. ounces, and add to the reserved portion. Uses. — This may be used the same as the Carmine solution for coloring all neutral elixirs, syrups, etc. When added to an acid preparation the color is very much weakened, and a pre- cipitate eventually forms. 441. Cochineal Fruit Red. Cochineal, I pound av. Cream of Tartar 2 ounces av. Alcohol, 1 pint. Water, sufficient to make 2 pints. Make in the same manner as No. 440. Uses. — This coloring may be used with fruit juices or syrups, wines or other mildly acid preparations, and gives with them a bright reel color. It may also be used with neutral liquids. 442. Cudbear Red. Cudbear I pound av. .Alcohol I pint. Water, sufficient to make 2 pints. olate and proceed in the same manner as is directed for making Cochineal Red (440). This is also known as Tinctura Persionis. Uses. — This makes an excellent red coloring, which maybe used for all neutral and arid preparations. It is similar to most of the " Fruil Coloring" that is sold by dealers in soda- water supplies. Acids brighten but do not weaken its color; with alkalies it gives a purple color. 248 Co I. ORES — COLORS. 443. Grass-Green. Fresh Lawn Grass, . * . . an)- convenient quantity. Alcohol, a sufficiency. Cut the grass fine, put it in a wide-mouthed bottle, as com- pactly as possible, and cover it with alcohol, let stand a few days, with occasional agitation, and pour off the liquid, which will be a dark-green color. The Cliloropliyll of the grass is dissolved by the alcohol. Uses. — This is used for coloring bay rum, and some liquors and cordials. As it is only slightly soluble in water, it is not recommended for aqueous preparations, a solution of sap- green being used for these. 444. Lemon-Yellow. For coloring Extract of Lemon or other spiritous solutions a natural lemon-yellow, chop the peel of lemons and cover them with alcohol, allow them to stand for a few weeks, then pour off the liquid. 445. Fustic-Yellow. Ground Fustic Wood, 1 pound. Diluted Alcohol, a sufficient quantity. Pack the Fustic in a percolator, pour sufficient diluted alco- hol upon it to cover it, and after standing 24 hours percolate, adding enough diluted alcohol through the percolator to make two pints of the percolate. Uses. — This may be used for imparting a yellow color to an} 7 preparation desired. For coloring Lemon Extract it is perhaps better to put the Fustic in the filter instead of using this. 446. Litmus Blue. The method of making a solution of Litmus has already been described (415). This solution maybe used for coloring neutral preparations, but is changed to red if acid is present. COLORES — COLORS. 249 447. Orange. For coloring orange flavoring extract made from Oil of Orange or other spiritous solutions a true orange color, chop the peels of oranges and cover them with alcohol, allow them to stand for a few weeks, then pour off the liquid. Saffron Orange may be made from Saffron in the same manner as 444, and is a fine coloring for many preparations. Tumeric, with alcoholic solutions, makes a light orange color. Annatto, or Arnatto, makes a reddish orange color in solu- tions. 448. Butter Color. Alain- proprietary preparations have been extensively sold for coloring butter. The first put upon the market were solu- tions of the coloring principles of arnatto or annatto in strong alkali. These had the disadvantages of being unpalatable and coloring the buttermilk, making it unfit for use, but are still used for coloring cheese. For coloring butter, Oil colors which combine with the butter only, and do not color the butermilk, are now used entirely. The best Butter Color may be made from Aintattoine,t\\e. coloring principle of Annatto, as follows: Annattoine, 4 ounces av. Salad ( )il ( Purified Cotton Seed Oil) suffi- cient to make I gallon. Rub the Annattoine with a portion (say I pint) of the Salad ( )il until it is a smooth mixture of uniform consistence. Grind the mixture very fine through a paint mill, or by continued rubbing in a mortar. Add it to the remainder of the Oil, and lie.ii by water-bath, with occasional stirring, for 4 hours or 1 : then, when cool, strain or filter through paper. As thus prepared this is equal to any <>f the Butter Colors on the market, provided only the right materials be used in making it. The Annattoine must be free from adulteration, and the Salad ( )il free from odi ir. 250 COLORES — COLORS. Colors for Powders, Etc. For coloring tooth powders and pastes and face powders, Solution of Carmine may be most advantageously used by first rubbing a portion of the powder thoroughly with it to form a stiff mass, and then incorporating this by rubbing with the remainder of the powder. If powdered carmine is used instead of the solution, great care must be taken to have it finely powdered and thoroughly mixed with the other ingredients. Other colors for powders are seldom required, but if they are, some harmless drug or pigment may be used, as charcoal or ivory black for black, tumeric for yellow, red saunders for a cheap red, etc. Show Bottle Colors. Colors for show bottles, to be satisfactory, must be bright, transparent, and permanent, able to stand the sunlight without precipitation and changes of temperature incident to the climate without freezing in winter or decomposing in summer. To meet all these requirements, solutions of mineral substances, containing a percentage of alcohol or acid sufficient to keep them, are generally best adapted. The aniline colors, although bright and beautiful, usually refract light, and are soon faded or decomposed by the action of sunlight. The following hints will be serviceable in preparing show- bottle colors : Use rain water or distilled water for making them, to avoid precipitates. If in a cold climate use 15 to 25 per cent, of alcohol to avoid freezing; in a warm climate much less, or even none, is required in most of the colors. Filtering properly is very important ; do not be satisfied until your colors are perfectly transparent. They may require to be filtered once or twice a year, but their improved appear- ance well repays the cost. Do not make the colors for the large globes too strong or dark ; deeper colors can be used in the small globes. COLORES — COLORS. 251 The following colors are readily made, simple and inexpen- sive, and will be found satisfactory: 449. Amber, Lemon or Orange. Any shade of yellow that may be desired, from a light amber or lemon to a deep orange, may be made by taking : Chromic Acid 5 to 60 grains. Water 1 gallon. Dissolve and filter. Bichromate of Potassium, which is usually used for making an amber color, deposits a coating of insoluble matter on the glass very difficult to remove, and soon renders the color dim. When Chromic Acid is used, this is avoided. 450. Blue. Sulphate of Copper, Blue Vitriol 2 pounds av. Sulphuric Acid S rl. ounces. Warm Water sufficient to make a gallon. Dissolve the Blue Vitriol in the Water, add the Acid and filter. This makes a very Deep Blue ; a Medium Blue may be made by diluting one half with water, a Light Blue by diluting with from 4 to 8 parts of water, according to shade desired. A fine Blue may also be made by dissolving Copper in Nitric Acid, and diluting with water. 451. Crimson. Alkanet Root 1 pound av. Oil of Turpentine 1 gallon. olate the Alkanet Root with the Oil of Turpentine. This may be made any lighter shade of crimson by diluting with Oil of Turpentine. This will not, of course, mix with other colors. 452. Green. Add to each gallon of Blue from 10 to 60 grains of chromic Arid, accord- ing to >1 1 desired. An) shadi of Green from a deep Blue-Green to a ri'h ( Hive may he made by varying the quantity of ( :hromic Acid. For Medium Green dilute the Green thus made with an equal quantity ol for Light Green dilute with from 4 to 8 parts of watei to Lhi 252 COLORES — COLORS. 453. Red or Scarlet. Cudbear yi ounce av. Nitric Acid 4 rl. ounces. Water 1 gallon. Mix, allow to stand 24 hours, and filter. To make Medium Red, dilute with an equal quantity of water ; to make Light Ned, or Pink, dilute with 4 to 8 parts of water, as required to produce the desired tint. 454. Violet. Cudbear 60 grains. Aqua Ammonia, 4 ounces. Water enough to make 1 gallon. Mix. allow to stand 24 hours and filter. For lighter shades of violet dilute with water. 455. Wine Color. Caramel Solution sufficient. Water 7 pints. Alcohol, .... 1 pint. Mix sufficient of the Caramel with the Water and Alcohol to make the desired color, and filter. A wine color may also be made by dissolving a few grains of iodine in a pint of alcohol, and adding water sufficient to make a gallon, then a few drops of nitric acid until the right shade is produced. The foregoing are the principal colors used in show bottles, but as many more as may be desired may be made by combining them. Some of the aniline colors make very fine effects, but are not so permanent as the pre- ceding. If two or three colors are desired in one globe, amber, blue, or green may be used to partly fill the globe, and the crimson poured carefully upon it to fill. The turpentine color will remain permanently at the top. Many other substances which are naturally colored may be used in show bottles, as fruit juices mixed with alcohol and water, oils of various kinds, either natural or colored, etc., but the foregoing are the cheapest and best. Colored Fires. Although the manufacture of colored fires may not prop- erly be included in the practice of pharmacy, the druggist is frequently called upon to prepare them. The following formulae are designed for making fires suit- able for theatrical illuminations, street parades, etc., which are the kinds usually required to be made by druggists. In the COLO RES — COLORS. 253 manufacture of fire-works a great variety of colored fires are made, but their formulas are not important to the druggist. In making colored fires it is necessary to observe some pre- caution in powdering and mixing the materials. The sub- stances should be separately powdered, then mixed by means of a wooden spatula, and the mixture kept in tin cans away from moisture or heat. The sulphur directed is sometimes omitted from the formulas on account of its disagreeable vapor, but it is not generally objectionable in the quantities used. 456. Blue Fire. Dark Blue may be made by taking : Sulphur, 1 ounce. Burnt Alum, 1 ounce. Carbonate of Copper, 1 ounce. Chlorate of Potassium 4 ounces. Shellac 1 ounce. Powder the drugs fine and mix with the Shellac in moderately coarse powder. Light Blue may be made by taking : Sulphur 1 ounce. Burnt Alum, 2 ounces. Chlorate of Potassium 4 ounces. Shellac 1 ounce. Mix the same as the preceding. 457. Green Fire. Dark Green may be made by taking : Nitrate of Barium 4 ounces. Boric Acid 1 ounce. Chlorate of Potassium 3 ounces. Sulphur 1 ounce. Shellac 2 ounces. Powder the drugs fine and mix with the Shellac in moderately coarse powder. Light Green may be made by taking : Carbonate of Barium 2 ounces. Sulphur 1 ounce. Chlorate of Potassium 4 ounces. Shellac 2 ounces. Mix as the preceding. 254 COLO RES — COLORS. 458. Red Fire. Dark Red may be made by taking : Nitrate of Strontium, 6 ounces. Chlorate of Potassium 2 ounces. Sulphur 1 ounce. Shellac 1 ounce. Powder the drugs fine and mix with the Shellac in moderately coarse powder. Light Red or Pink may be made by using only half the quantity of the Nitrate of Strontium, or as follows : Chalk 2 ounces. Sulphur, 1 ounce. Chlorate of Potassium, 3 ounces. Charcoal X ounce. Nitrate of Potassium, 3 ounces. Shellac 1 ounce. Powder and mix as the preceding. 459. Violet Fire. Burnt Alum, 1 ounce. Carbonate of Potassium, 1 ounce. Sulphur 1 ounce. Chlorate of Potassium, 4 ounces. Shellac 1 ounce. Powder the drugs fine and mix with the Shellac in moderately coarse powder. 460. White Fire. Nitrate of Potassium, 8 ounces. Charcoal % ounce. Sulphur, 1 ounce. Shellac 1 ounce. Powder and mix as the preceding. 461. Yellow Fire. Sulphur 1 ounce. Dried Carbonate of Sodium, 2 ounces. Chlorate of Potassium 5 ounces. Shellac 1 ounce. Powder and mix as the preceding. The foregoing are all the Colored Fires that are generally required for theatrical illuminations, street parades, etc., but a great variety of other colors CONFECTIONES — CONFECTIONS. '2oo may be made by variously combining them, and many shades of color may be made by varying the quantities of the ingredients used. Liquid Colored Fires or Flames. These may be made by dissolving certain substances to saturation in Al- cohol or other liquids which will dissolve them, and burn with rapidity. They are best ignited in a shallow iron pan, which for safety should be set in a shallow pan of water. Considerable caution is required in burning these liquids, that accidents may be prevented. The substances used should be finely powdered and triturated with the Al- cohol in a mortar. Blue may be made by dissolving Acetate of Zinc in Alcohol ; Gran, bv dissolving Boric Acid in Alcohol ; Red, by dissolving Nitrate of Strontium in Alcohol, or by making a strong Tincture of Lycopodium ; Violet, bv dissolv- ing Carbonate of Potassium in Alcohol ; Yellow, by dissolving Nitrate of Sodium in Alcohol ; White, by dissolving Camphor in Alcohol. Another method of exhibiting Colored Fires, and perhaps the best of all, is to mix the finely powdered substances which produce the colors, as above, with a moderately thick Solution of Shellac in Alcohol. They are thus sus- pended, and when burned give forth their characteristic color. CONFECTIONES — CONFECTIONS. Confections are substances resembling soft, solid extracts, prepared by incorporating medicines with sugar or other sac- charine matter and aromatics. They were once very popular, but arc now little used. Similar preparations, varying some- what in consistence and manner of making, were formerly known as Electuaries and Conserves, and as such they are still called for occasionally. Confections and Conserves. Of the Confections formerly official but two only were re- tained in the U. S. iSNES — CONFECTII >NS. beating or pounding with sugar, until they are thoroughly in- corporated. The proportion of sugar used varies from double to three times the quantity, by weight, of the fresh leaves. The following formulae are representative of the whole class : 462. Conserve de Cochlearia. Confection of Scurvy Grass. Scurvy Grass Leaves, fresh, 1 part. Sugar 3 parts. Beat the two substances in a mortar until they are reduced to a pulpy- mass, which should then be passed through a hair-cloth sieve by the aid of a flat-ended wooden spatula. In French Pharmacy the leaves or flowers of several plants containing considerable water are made into Conserves in the same manner and with the same proportion of sugar as sorrel, fumitory, the cresses, peach and violet flowers, etc., are made into Confections in this manner. Other Conserves of leaves which contain considerable moisture are made in the same proportion, but those containing less moisture are made as follows : 463. Conserves de Laurier-Cerise. Confection of Cherry-Laurel Leaves. Cherry-Laurel Leaves, fresh 1 part. Sugar, 2 parts. Make in the same manner as the preceding. A great variety of leaves and flowers are made into conserves in this proportion. U. S. and Br. Official Confections. The following are the confections official in the U. S. and Br. Pharmacopoeias : 464. Confectio Opii, Br. Confection of Opium. Compound Powder of Opium, . 100 grains or 1 part. Syrup, - . . 300 grains or 3 parts. Mix. Dose, 5 to 20 grains. CONFECTIONES — CONFECTIONS. 257 As the compound powder of Opium contains 10 per cent, of opium, this is about the same as the U. S. 1870 prepara- tion, which was made as follows: Opium, in fine powder, 270 grains. Aromatic Powder, 6 tr.ounces. Clarified Honey, 14 tr.ounces. Mix, etc. This confection was much used during the past century under the names of Theriaca and Mithridate i wonderful virtues being ascribed to it. It is still occasionally called for by those names. 465. Confectio Piperis, Br. Confection of Pepper. Black Pepper, in fine powder, . 2 ounces or 2 parts. Caraway Fruit, in fine powder, . 3 ounces or 3 parts. Clarified Honey, 15 ounces or 15 parts. Rub them well together in a mortar. Dose, 60 to 120 grains. 466. Confectio Rosas Caninas, Br. Confection of Hips. Hips, deprived of their seed-like fruits, . . I part. Refined Sugar 2 parts. Beat the Hips to a pulp in a stone mortar, and rub the pulp through a sieve, then add the sugar and rub them well together. To American druggists, who are unacquainted with " Hips," it may be explained that it is the oval red fruit of the dog rose or wild brier, common in fields and hedges. 467. Confectio Rosae, U. S. Confectio Rosce GallicNFECTIONES — CONFECTIONS. Rub the Rose (petals) with the Rose Water, heated to 6f C. (149° F.), then gradually add the Sugar and Honey, and beat the whole together until thoroughly mixed. The British formula is: Fresh Red-Rose Petals, . .... I part or 1 pound. Refined Sugar, 3 parts or 3 pounds. Beat the Petals to a pulp in a stone mortar, add the Sugar, and rub them well together. This is used in making several official pills, and is much prescribed in pill masses, etc. 468. Confectio Scammonii, Br. Confection of Scammony. Resin of Scammony, in powder, . 6 oz. or 48 parts. Ginger, in powder, 3 oz - or 2 4 P arts - Oil of Caraway, % A.oz. or 2 fl.parts. Oil of Cloves, }8 fl-oz. or 1 fl.part. Syrup, 6 fl - oz - or 48 fl-parts. Clarified Honey, 3 oz. or 24 parts. Rub the Powders with the Syrup and the Honey into a uni- form mass, then add the Oils and mix. Dose, 10 to 30 grains. 469. Confectio Senna. Confection of Senna. The U. S. formula is: Senna, in No. 60 powder, 10 ounces av. Coriander, in No. 40 powder, .... 6 • ounces av. Cassia Fistula, bruised, 16 ounces av. Tamarind, 10 ounces av. Prune, sliced, 7 ounces av. Fig bruised, 12 ounces av. Sugar, in coarse powder, 5° ounces av. Water, a sufficient quantity, .... S7 l A A.ounces. "Place the Cassia Fistula, Tamarind, Prune and Fig in a close vessel with 3 pints of water, and digest for 3 hours by COXFECTIONES — CONFECTIONS. 259 means of a water-bath. Separate the coarser portion with the hand, and rub the pulpy mass first through a coarse hair sieve and then through a fine one, or through a muslin cloth. Mix the residue with the remainder of the water, and having digested the mixture for a short time, treat as before, and add the pro- duct to the pulpy liquid first obtained. Then by means of a water-bath dissolve the Sugar in the pulpy liquid and evapo- rate the whole until it weighs 84 ounces avoirdupois. Lastly, add the Senna and Coriander, and incorporate them thoroughly with the other ingredients while yet warm." The finished product should weigh 100 ounces av. The Br. formula does not differ materially from this, except that extract of liquorice is added. Confections similar to this are put up in masses of about a drachm covered with silver leaf, and sold as Fruit Laxatives or Cathartic Lozenges. 470. Confectio Sulphuris, Br. Confection of Sulphur. Sublimed Sulphur, 4 ounces or 4 parts. Acid Tartrate of Potassium, . . 1 ounce or 1 part. Syrup of Orange Peel, .... 4 fl. ounces or 4 fl. parts. Tragacanth, in powder, . . .18 grains or -} T part. Rub them well together. Dose, 60 to I 20 grains. 471. Confectio Terebinthenae, Br. Confection of Turpentine. Oil of Turpentine 1 II. ounce or 1 fl.part. Liquorice Root, in powder, . 1 ounce or 1 part. Clarified Honey, 2 ounces or 2 parts. Rub the Oil of Turpentine with the Liquorice, add the Honey, and mix to a uniform consistence. Dose, 60 to [20 grains. 260 CONFECTIONES — CONFECTN >NS. Other Confections, Conserves and Electuaries. The foregoing official Confections embrace nearly all for which there is a demand, except those occasionally called for in recipes from old works on medicine and pharmacy. No class distinction is now made between Confections, Con- serves, and Electuaries, but they were formerly classified sep- arately, according to their characteristics. Confections being of firmer consistence, and usually made of dry ingredients mixed with sugar, and made up in the form of an extract. Con- serves being of about the same consistence, but prepared from fresh leaves, flowers, fruit, or other vegetable matter mixed with sugar to a stiff pasty mass. Electuaries being of much softer consistence, and prepared generally by mixing powdered substances with syrup, honey, or other saccharine liquids. This distinction is now done away with, and all are classed under the head of Confections, but are liable to be called for by old names. The following are the most important: 472. Aromatic Confection. — Aromatic Powder. 4 tr. ounces, mixed with Clarified Honey 4 tr. ounces, or a sufficient quantity to make a mass of the proper consistence. This was formerly official in the U. S. P. 473. Confection of Almonds or Almond Paste. — Sweet Almonds, 8 ounces; White Sugar, 4 ounces; Powdered Acacia, 1 ounce. Blanch the Almonds, and beat them with the other ingredients until all are reduced to a uniform smooth confection. Milk of Almonds may be prepared from this confection by rubbing a por- tion of it with water and straining through cloth. 474. Confection of Orange Peel. — Sweet Orange Peel, recently sepa- rated from the fruit by grating, 1 tr. ounce ; Sugar, 3 tr.ounces. Beat them together into a confection. This was formerly official in the U. S. P. Confet turn of Lemon may be made in the same way. 475. Candied Sweet Flag. — Fresh Sweet Flag or Calamus is peeled, cut in pieces or sliced, and simmered with syrup for several hours, then drained and dried. Many other confections of fresh aromatic roots, barks, fruit and (lowers, may be prepared in the same manner. Angelica root, ginger root, lemon and orange peel, rose and violet flowers, and some of the aromatic seeds or fruits, as caraway, fennel, etc., are thus prepared. Most of the other confections, conserves and electuaries are of the past, and so seldom called for that their formulas are omitted. CORDIALES — CORDIALS. 261 CORDIALES — CORDIALS. In pharmacy a few preparations similar to elixirs are prepared and dispensed under the name of Cordials. They have prob- ably derived their name from their similarity to the French Ratafias, Cordials or Liqueurs, which are highly flavored, stimulating beverages, weak in spirit and sweetened. In this class only those cordials which are well known to Amer- ican pharmacy will be included, the others being mentioned under the heading Liqueurs, Ratafias, etc. Many preparations that are popularly known as Cordials will be found among the Elixirs, Proprietary Remedies, etc. 476. Calisaya Cordial. Calisuya Bark 4 ounces av. Wild Cherry Bark, 4 ounces av. Orange Peel, fresh 4 ounces av. Cinnamon Bark 2 ounces av. Anise Seed, y 2 ounce av. Angelica Seed or Root, I drachm. Cloves, I drachm. Cardamom Seed I drachm. Alcohol, 2 pints. Rose Water I pint. Sugar 3 pounds. Water sufficient to make 1 gallon. Chop tin- ( )range Peel f-inc and grind the drugs to a coarse powder, pour the Alcohol upon them and macerate for 48 hours; then pour off the Alcohol, transfer the drugs to a per- colator, pour the alcoholic tincture upon them and percolate. When no more percolate will drop add to the drugs in the percolator, first, the Rose Water and then water, continuing the percolation until 6 pints altogether of percolate is oh tained. Filter clear, dissolve the sugar in the filtrate, and add enough water passed through the drugs in the percolator to make a gallon of the Cordial. It may be colored red, if de- sired. 262 CORDIALES — CORDIALS. This is considerably used to disguise the taste of quinine, and other disagreeable medicines, and also as a pleasant tonic cordial. Dose half a wine glassful. 477. Curacao Cordial. Aromatic Cordial. Elixir Curacoa. Bitter Orange Peel, in very coarse powder, 2 ounces av. Cloves, in fine powder, 80 grains. Cinnamon in fine powder, 80 grains. Cochineal in fine powder, 60 grains. Oil of Sweet Orange, 1 fl. drachm. Orange Flower Water, triple, .... 8 fl. ounces. Holland Gin, I pint. Alcohol 2 pints. Sugar, 3 pounds av. Water sufficient to make 1 gallon. Pour the Alcohol upon the drugs, add the Oil of Orange, and macerate for 2 days ; then add the Gin and 3 pints of Water, macerate for a week, filter and add the Sugar and enough water to make a gallon of the cordial. Fresh sweet orange peel, half a pound, may be used instead of the bitter orange peel. Curacao Cordial may also be made from the oils as follows : Oil of Sweet Orange, 2 fl. drachms. Oil of Cloves, 10 minims. Oil of Cassia, 10 minims. Oil of Neroli, 15 minims. Sugar, 3 pounds av. Alcohol, 2 l / 2 pints. Water, 4 pints. Mix the Oils with the Alcohol, add the Water, and, after macerating a day or two, filter, dissolve the Sugar in the fil- trate, and color with Cochineal Coloring. Curacao Cordial is used as a pleasant vehicle for the administration of medicines, and as an adjuvant. It is also frequently employed as the base of various elixirs. CORDIALES — CORDIALS. CREASOTUM — CREASOTE. 263 478. Gentian Cordial. Gentian Root, 2 ounces av. Orange Peel, fresh, 4 ounces av. Cinnamon Bark, 2 ounces av. Licorice Root, 2 ounces av. Wild Cherry Bark, 2 ounces av. Cardamom Seed, y 2 ounce av. Angelica Root or Seed, 1 drachm. Alcohol, .2 pints. Water, 5 pints. Sugar, 2y 2 pounds. Chop the Orange Peel fine and grind the drugs to a coarse powder ; macerate for two days with the Alcohol, and pour off; transfer the drugs to a percolator and percolate with the al- coholic tincture ; add the Water in the percolator, and when all the percolate is obtained, dissolve in it the Sugar, and filter. This is a pleasant appetizing Cordial and tonic. Dose half a wine-glassful. 479- CREASOTUM — CREASOTE. Crcasote is an oil)- liquid of a smoky odor, similar in com- position and characteristics to carbolic acid. It is obtained by the dry distillation of wood, and from smoke, pyroligneous acid, soot, etc. It is frequently called for as Oil of Soot. But little true Wood Crcasote is now to be found in the market, it being mostly adulterated with, or entirely sub- stituted by, Carbolic Acid. Uses. — Creasote is used in medicine in minute doses to check internal mucous irritation, and as a cleansing application in ointments, for ulcers and sores; but it is best known as a remedy for toothache, for which it internally is from y£ to 2 minims, largely diluted. ; quite popular. The dose ) tin' form of emulsion or 264 CUPRUM — COPPER. CUPRUM — COPPER. Symbol, Cu ; Atomic weight, 63.5; sp. gr. 8.9. Copper is a well-known metallic element, extensively em- ployed in the arts and industries of the world, and used by many nations as a small-money coin. It is found native, and combined in the form of ore in all parts of the world. In the arts, alloys of copper are much used. Bronze, brass, german silver, gun metal, bell metal, and many others being made by combining it with various other metals. It is also used as an alloy of gold in gold coins and in making jewelry. The following formulae show the composition of some of the principal alloys into which copper enters : 480. Brass. — Copper and zinc combine together in all proportions to form brass, which varies in color according to the proportion of the metals. Prince Rupert's Metal, Pinchbeck and Mannheim Gold, contain 75 to 80 per cent, of copper, and are considerably used for making cheap jewelry. Tombac contains 84.5 per cent, of copper and 15.5 per cent, of zinc. It is used for making "Dutch metal," an imitation of gold leaf ; used extensively for cheap work. Casting Brass varies in composition as required for different purposes, but the usual proportion is about 70 per cent, of copper with 30 per cent, of zinc. Other metals are sometimes added in small proportions. By lacquering brass with various kinds of lacquer it is made to imitate bronze. 481. Bronze. — This is made from copper and tin in varying proportions. It is used in making statuary and many other articles. Varieties of bronze are known as bell metal, which is composed of about 78 parts of copper to 22 parts of tin, and gun metal, which contains 90 parts of copper and 10 of tin. The ordinary casting bronze contains from 80 to 85 per cent, of copper, 15 to 20 per cent, of tin, and 1 or 2 per cent, of zinc. Phosphor Bronze contains phosphorus, and is used for making ordnance and for other purposes. Gold Bronze is brass or bronze in very fine powder; used as a substitute for -old for gilding, etc. 482. German Silver or Nickel Silver.— This is a white metal, much em- ployed as a basis for plated ware and ornamental artistic metal work. It is composed of copper, nickel and zinc in varying proportions, to which other metals are frequently added. The average proportion for spoons, forks, etc., is 2 parts of copper, 1 of nickel, and 1 of zinc. For other purposes larger or smaller proportions of the metals are used. CUPRUM — COPPER. 265 Salts of Copper, In pharmacy the Salts of Copper are considerably used for various purposes, and in medicine they are somewhat employed in solutions, ointments, and plasters for external use, but seldom internally. The following are the official Salts of Copper : 483. Cupri Acetas. Acetate of Copper. Cu(C 2 H 3 2 ) 2 .H 2 0. This is most conveniently prepared by precipitating a con- centrated solution of Acetate of Lead with Sulphate of Cop- per, then filtering the solution, evaporating and crystallizing. This is called Normal Cupric Acetate to distinguish it from the Basic Cupric Acetates, or Verdigris, which is a mixture of sev- eral acetates of copper. It is used in some plasters and oint- ments. 484. Cupri Nitras, Br. Nitrate of Copper. Cu(NO,) 2 3.H 2 0. This salt is official in the Br., but not in the U. S. Pharma- copoeia. It may be made by dissolving copper in nitric acid diluted with water, evaporating the solution and crystallizing. Its solution makes a permanent blue for show bottles. 485. Cupri Sulphas. Sulphate if ( 'tppcr, Blue / '/trio/. CuS0 4 .5ll ,'). This salt is most commonly known by the name of Blue Vitriol or Blue Stone. It is the most used of any of the coppei 266 CUPRUM — COPPER. salts, and may be conveniently made by dissolving scraps of copper in sulphuric acid diluted with water, by the aid of heat, then evaporating the solution and crystallizing. Dried or Anhydrous Sulphate of Copper is made by heating Sulphate of Copper until its water of crystallization has vapor- ized, then reducing it to a powder. It is used as a test for alcohol and as an escharotic. Uses. — This salt is considerably used in batteries for gener- ating electricity, for coloring and dyeing purposes, and in medi- cine for making various cleansing washes, liquids, etc. It is sometimes given as an astringent in doses of }^ to 2 grains, and as a quick emetic in doses of 5 to 10 grains. Of the Salts of Copper not officially recognized, the follow- ing are somewhat used : 486. Ammoniated Copper.— Cu(NH 3 ) 4 S0 4 .H 2 0. — This salt was for- merly official. It is made by rubbing together in a mortar 240 grains of sulphate of copper and 360 grains of carbonate of ammonium until efferves- cence ceases, then collecting the salt and pressing in bibulous paper. 487. Arseniate of Copper.— Cu 3 As„0 8 . — By adding a solution of sul- phate of copper to a solution of arseniate of sodium, then collecting and drying the precipitate. 488. Bromide of Copper. — CuBr 2 . — By dissolving oxide of copper in hydrobromic acid, evaporating and crystallizing. 489. Carbonate of Copper.— CuC0 3 . — By adding a solution of carbonate of sodium in excess to a solution of sulphate of copper, and warming. This is a green pigment. 490. Citrate of Copper.— By heating a solution of acetate of copper with citric acid and crystallizing. 491. Chloride of Copper. — CuCl 2 . — By dissolving copper scraps in hydro- chloric acid, evaporating the solution and crystallizing. 492. Oxides of Copper. — Suboxide of Copper, Cuprous Oxide.— Cu 2 0. — By igniting copper in fine powder in the atmosphere, or by precipi- tating a solution of sulphate of copper with grape sugar and caustic potassa, collecting and drying the precipitate. Oxide of Copper, Lupric Oxide — CuO. — By heating the nitrate or car- bonate of copper to redness, and continuing the heat until it remains a black heavy powder. Many other salts of copper are formed with other acids, but they are unim- portant. CYANOGEN. DECOCTA — DECOCTIONS. 267 493. CYANOGEN. CN or Cy. Cyanogen is a gaseous radicle, discovered by M. Guy Lussac, in 1 81 5. It is most readily obtained by igniting dry cyanide of mercury in a small retort, and collecting the gas over mer- cury. It is colorless, and its odor resembles that of freshly- bruised peach kernels. It is important in chemistry and phar- macy as forming a class of acids with hydrogen and oxygen, which form salts with metals and alkaline bases called Cyanides or Cyannrets. Its acids are as follows : 494. Cyanic Acid — HCNO. — Made by distilling cyanuric acid deprived of its water of crystallization in a retort, and collecting the vapor in a well- cooled receiver. Cyanates are salts in which the hydrogen of cyanic acid is replaced by some metallic base or other basic radical. 495. Hydrocyanic Acid — HCN — Prussic Acid. — This is obtained by heating ferrocyanide of potassium 1% ounces with sulphuric acid 1 fl. ounce (imperial measure) and 10 fl. ounces of water in a flask, and distilling, collect- ing the gaseous product in water, or water mixed with alcohol, until any desired percentage is obtained. The official Diluted Hydrocyanic Acid contains 2 per cent, of real Hydrocyanic Acid. (See page 61.) DECOCTA— DECOCTIONS. Decoctions which were formerly popular forms of preparing medicines have gradually given place to more scientific prepa- rations, and are now seldom used. The process of Decoction is to boil the vegetable substance's for from 10 to 15 minute's in water in a covered vessel, and then cool and pour off the liquid. It is obvious that the water- bath percolator is the most convenient apparatus to use for this purpose, as there is no danger of burning the drugs or excessively heating the mixture, and when the boiling is completed the liquid may be drawn off by the stop-cock. The 268 DECOCTA — DECOCTIONS. following general directions for making Decoctions are there- fore given : 496. Decoctions by Water-bath Percolation. The substance, coarsely comminuted, . 1 ounce av. Water enough to make 10 fl. ounces. Having adjusted the perforated diaphragm or strainer in the bottom of a small-sized water-bath percolator, put the substance in the percolator and pour the water upon it. Cover the per- colator closely with the cover, and, having filled the vessel sur- rounding the percolator with water, heat to boiling. Boil for 15 minutes and draw off the liquid by mean of the stop-cock, adding enough water through the percolator to make 10 fl. ounces of the product when cool. The U. S. official directions for making Decoctions are to take of The substance, coarsely comminuted, ... 1 part. Water sufficient to make 10 parts. Put the substance into a suitable vessel provided with a cover, pour upon it 10 parts of cold water, cover and boil for 15 minutes, then strain and add water enough to make the product 10 parts. Only two decoctions are now official in the U. S. P. They are as follows : 497. Decoctum Cetrariae. Decoction of Cctraria. Cetraria (Iceland Moss), 364 grains. Water enough to make a pint. Cover the Cetraria with cold water for half an hour, express and throw away the liquid. Then boil the drug with a pint of water for half an hour, strain and add enough cold water through the strainer to make a pint of the finished product. DECOCTA — DECOCTIONS. 498. Decoctum Sarsaparillae Compositum. Compound Decoction of Sarsaparilla. Sarsaparilla, crushed, 729 grains. Sassafras, in coarse ponder, 156 grains. Guaiacum Wood, rasped, 156 grains. Liquorice Root, crushed, 156 grains. Mezereum, crushed, 78 grains. Water enough to make a pint. Boil the Sarsaparilla and Guaiacum Wood for half an hour with a pint of water; then add the Sassafras, Liquorice and Mezereum, cover the vessel well and macerate, with gentle heat for two hours ; then strain and add enough water through the strainer to make a pint of the finished product. The same directions should be followed when made by water- bath percolation. Of the 13 Decoctions official in the 1885 Br. P., nearly all are simple decoctions, which may be included in the general directions for making Decoctions; the following require special mention : 499. Decoctum Aloes Compositum. Compound Decoction of Aloes. Soctorine Aloes, ]/ 2 ounce av. Myrrh, ^ ounce av. Saffron ]^ ounce av. Carbonate- of Potassium ] + ' ounce av. Extract of Liquorice 2 ounces aw Compound Tincture of Cardamoms, 13 11. ounces. Imp. Distilled Water sufficient to make 50 flounces. Imp. Boil the extracts, etc., in a pint 120 ounces) of water for 5 minutes, add the Saffron, cool, add the Tinct ure of Cardamoms, macerate for 2 hours, then strain through flannel, adding water through the strainer to make the required measure. 2?<> DECOCTA — DECOCTIONS. DESTILLAT.E. 500. Decoctum Cinchonae. Decoction of Cinchona. Red Cinchona Bark in No. 20 powder, . 1^ ounce av. Distilled Water, 20 fl. ounces. Boil for 10 minutes in a covered vessel, strain the decoc- tion, when cold, and pour as much distilled water over the contents of the strainer as will make the strained product measure 20 ounces. Decoction of Pareira and of Oak Bark are made in the same proportion and manner by the Br. P. 501. Decoctum Granati Radicis. Decoction of Pomegranate Root. Pomegranate Root Bark, sliced, . . 2 ounces av. Distilled Water, 40 fl. ounces, Imp. Boil down to 20 fl. ounces and strain, making the strained product up to 20 fl. ounces if necessary by adding water through the strainer. The remaining official British Decoctions are all made in the same manner as 500. Decoctions of Logwood, Broom, Dan- delion, and Iceland Moss, are made, 1 ounce of the drug to 20 of water; of Barley and Poppy, 2 ounces to 20 of water; of Sarsaparilla, 2 r / 2 ounces to make 20 fl. ounces of the decoction, The Compound Decoction of Sarsaparilla does not differ materially from the U. S. All other Decoctions may be made by the general official formula, or by water-bath percolation, as heretofore described, in the proportion of one part of the drug to make 10 parts of decoction. DESTILLAT^ — DISTILLATES. All preparations obtained by the process of distillation are Distillates, in the same sense that all preparations made by DEXTRINUM — DEXTRIN. 271 percolation are percolates, but as distillation is a process rather than a characteristic of the substances employed, the distillates are classed under the various headings where they properly belong. The process of distillation in pharmacy is of great import- ance. It is described on page 26. The preparations in which the process is employed will be found in nearly all classes of fluid galenicals. 502. DEXTRINUM — DEXTRIN. Artificial Gum, British Gum. When starch is subjected to the action of dilute acids at a boiling temperature, it is converted into a substance resem- bling gum, which is called Dextrin. The same also occurs when potato starch is heated to about 36o°F. for an hour or two in an oven, and in this manner it is usually prepared com- mercially. In making an infusion of malt the Diastase acts upon the starch, first converting it into dextrin and then into sugar. Dextrin is much used in the arts for various purposes, as a substitute for gum. It is extensively used for making paste and mucilage, and as a dusting for pills, and upon irritated surfaces. Dextrin Syrup or Starch Syrup is ;i syrup of high conversion, containing 40 to 45 per cent, of grape sugar, and about the same of dextrin. It is considerably used as a table syrup under various fancy names, and is frequently directed in medicinal 1 1 impounds. 503. Dextrin Mucilage. — A good mucilage may be made by dissolving I part <>f dextrin in 2 parts of hot water. The proportions may be varied, making a mucilage thick or thin, as desired. DIALVSAT.E — DIALVSATES. DI ALYSAT^ — DI ALYSATES. A number of preparations made by the process of Dialysis have recently been introduced to pharmacy and are somewhat used, the best known being Dialysed Iron. The process of Dialysis is described on page 24. The following are the preparations made by the process, but it is evident that their number may be largely increased. As Dialysis is a process rather than a characteristic of the preparation, the Dialysates might, perhaps, be more properly classed elsewhere, but, as they are so few, they are given under this heading. 504. Ferrum Dialysatum. Dialysed Iron. A Solution of Dialysed Iron or Liquor Ferri Dialysatus may be prepared as follows. It is official in the Br. P. : Strong Solution of Perchloride of Iron (Br. P., sp. gr. 1.42), 14 fl. ounces. Water of Ammonia, Water, of each, a sufficient quantity. Mix 12 fl. ounces of the Iron Solution with 1 gallon of water in an earthenware jar that will hold 3 gallons, and add, with constant stirring, Water of Ammonia until the iron is all pre- cipitated and the liquid remains alkaline. Let the precipitate settle, and wash it with water, as is directed for washing pre- cipitates (page 44), until the washings give no precipitate, with solution of nitrate of silver. Then transfer the precipitate 1 Ferric hydrate) to a calico strainer; drain and express the water. While still moist mix the precipitate in a jar with 2 fl. ounces of the Solution of Iron, same as previously used; warm and stir them occasionally for a day or two until all has dissolved that will; then dialyse the solution as directed, changing the water every day for 10 or 12 days, or until the preparation is free from styptic taste, and clear, and make the dialysed solution measure 56 fl. ounces. This should contain 5 per cent, of Oxide of Iron, and be of sp. gr. 1.407. DIALYSAT.E — DIALYSATES. DIASTASE. 273 Uses. — Dialysed Iron in solution has been quite a popular form of administering iron as a tonic. It is given in doses of 10 to 30 minims. Dialysed Iron in Scales may be made by evaporating the solution of Dialysed Iron to a syrupy consistence and spread- ing upon glass. The dose is from I to 5 grains. 505. Dialysate of Aconite. Aconite Leaves in very coarse powder, . 16 ounces av. Water, a sufficient quantity. Exhaust the drug by percolating in the water-bath perco- lator with hot water and dialyse the percolate, saving the sev- eral waters with which the dialysis is conducted, and evaporat- ing, by means of a water-bath, to half a pint. To this add half a pint of alcohol and filter. It will be noted that in this case it is not the contents of the dialyser that is saved, but the liquor which passes through the dialyser, and contains all but the colloid matter of the percolate. The Dialysate has the same strength of the valuable medi- cinal principles of the drug as the fluid extract. Dialysate of Belladonna, and of many other drugs, may be made in the same general way. The process of dialysis is sometimes used to separate alka- loids or other principles of plants from colloid principles. 506. DIASTASE. The peculiar ferment in malted grains which converts the starch first into dextrin and then into grape sugar, or dextrose, is called Diastase. It acts as a very powerful ferment; one pari being sufficient to convert 2,000 parts of starch into grape sugar. The chief value of extract of malt consists in the of diastase that it contains after converting the starch and dextrin of the malt into sugar. If this is destroyed, therefore, by 1 xcessive heat or other means in making extract of malt, the value of the extract is very much impaired. 274 ELATERIUM. ELIXIRIA — ELIXIRS. Diastase may be obtained in an impure condition by making an infusion of malt — not heating over 160 F. — filtering, and adding the filtrate to alcohol, which precipitates the Diastase in the form of a white powder, freely soluble in water. It is an expensive chemical, seldom used, and rarely made, except by manufacturing chemists. 507. ELATERIUM. This is obtained from the very nearly ripe squirting cucum- ber fruit by cutting the fruit lengthwise and lightly pressing out the juice, then straining through a hair-cloth sieve and setting aside to deposit. The supernatant liquid is then poured off, the sediment poured on a linen filter and dried by gentle heat on porous tiles. It requires about 40 pounds of the fruit to yield half an ounce of Elaterium ; it is therefore expensive and liable to adulteration. Uses. — Elaterium is used as a purgative or hydrogogue cathartic, especially in dropsical conditions. It is generally given in the form of pills or powders, but its solution in alco- hol is more effective. The dose is from ^ to -£$ grain, repeated if necessary. Elaterin — C 20 H 28 O 5 — is a neutral principle extracted from Elaterium by treating it with alcohol, evaporating the alcoholic tincture to the consistence of a thin oil, and pouring it while warm into a weak boiling solution of potassa. The Elaterin crystallizes, leaving the green resin in solution. The dose of Elaterin is ^ of a grain. It is official in the U. S. P. ELIXIRIA — ELIXIRS. The class of preparations known in pharmacy as Elixirs, includes a great variety of medicines widely dissimilar in char- acter. The first Elixirs were acid preparations prepared by alchemists and the early pharmacists. They were supposed to possess wonderful virtues. " Elixir Album" and " Elixir Ru- brum" were the products of wonderful manipulations, and ELIXIRIA — ELIXIRS. 275 were said to transmute the baser metals into pure silver and gold, and cure "most diseases in man's body." Later on, Paracelsus originated the " Elixir Proprietatis," or " Elixir of Long Life"; and still later the earlier pharmacists gave us " Elixir Paregoricum," " Elixir Salutis," " Elixir Stomachi- cum," " Elixir Vitriol," " Elixir Halleri," and a score of others, from which have descended some of our most popular tinc- tures and other similar preparations. American Pharmacy has adopted the name " Elixir" for a class of flavored, sweetened, weakly alcoholic preparations, in which medicinal substances are exhibited in pleasant, pala- table form, and which are designed to mitigate the aversion to medicines so common to invalids and delicate people. Since Elixirs have assumed this form and mission their popularity has greatly increased, and, from two or three proprietary Elixirs that were known thirty years ago, the number has grown to hundreds, and they have come to take the place, to a great extent, of tinctures and other preparations that were formerly popular forms of medicine. The number of Elixirs has increased so rapidly, and their combinations are so varied, that it is almost impossible for the druggist to keep a stock of all of them sufficient to meet the demands of his business. The formula; for Elixirs which follow are therefore arranged so that by keeping a few of the leading bases on hand, their combina- tions can be readily made by adding various solutions, etc., and thus save the trouble and expense of keeping so large a variety of Elixirs on hand as would be required to supply the demands of the business. 508. Elixir Flavoring. In former editions of FENNER'S FORMULARY this was called, simply. " Flavoring," but we have now adopted the above title as being more expres- sive. ( )il of Sweet Oraflge, fresh, 4 tl. ounces. Oil "I" Caraway Seed 2 tl. drachms. Oil of Coriander Seed, 2 fl.drachms. < )il of Cassia 2 ll. drachms. oil of Anise, or Oil of Nutmeg, . . . 1 fl.drachm. Alcohol, 1 5 ll. ounces. 276 ELIXIRIA — ELIXIRS. Mix. This is a strong Flavoring, of which one ounce is sufficient for a gallon of Elixir. Many Elixir Flavoring formulas have been proposed and published, but no other has been found equal in all respects to the foregoing, provided only that good materials are used in making it. Oil of Orange, it is well known, deteriorates by age and exposure, becoming terebinthine in odor, therefore it is necessary that only sweet fresh Orange Oil be used, for upon that depends the flavor of the Elixir. Oil of Caraway Seed, not Oil of Caraway Chaff, should be used. Deodorized Alcohol, or Cologne Spirit, should be employed in making the Flavoring as well as in making all the Elixirs. When dissolved in the alcohol the flavoring will keep for any length of time ; it is therefore best to get the oils as fresh as possible, and make them up, while fresh, in the flavoring. Many formulas have been published for making Elixir Flav- oring from the substances, instead of their oils : as fresh Orange Peel, Caraway Seed, Cassia Bark, etc.; but their flavor when thus prepared is uncertain, and besides the substances them- selves contain astringent principles, which make inky mixtures when combined with salts of iron in solution, and are other- wise objectionable for the purpose. We therefore advise only the Flavoring made from the Oils, and from long experience choose the formula given (508) in preference to any other. The New-York and Brooklyn Formulary publishes a formula quite similar, under the title, 509. Spiritus Aurantii Compositus. Compound Spirit of Orange. Oil of Bitter Orange 4 fl.ounces. Oil of Lemon . 1 fl.ounce. Oil of Coriander 160 minims. Oil of Star Anise 40 minims. Deodorized Alcohol, enough to make 20 fl.ounces. Mix them. This may be used, if preferred, in the same proportion and manner as is directed in these formulae for Elixir Flavoring (508). One objection to this is, that it is much more difficult to obtain a fresh fine ( )il of Bitter Orange than of the Sweet Orange, although when fresh it is to be preferred to it. ELIXIRIA — ELIXIRS. 277 510. Soluble Flavoring. FOR ELIXIRS, ETC. In former editions of Fenner'S Formulary this has been called " Pre- pared Flavoring "; but we have now adopted the above title as being more expressive. The foregoing Flavoring (508) will not mix with the Elixir base without making a cloudy or milky mixture, and Elixir made with it has to be filtered through Carbonate of Magne- sium or some other alkaline or absorbent material to make a clear solution. It is frequently desirable to have an Elixir Flavoring that will make a clear solution when added to an elixir base, perco- late or syrup, and the following is designed for that purpose : Elixir Flavoring (508), 16 fl. ounces. Carbonate of Magnesium, .... 4 ounces av. Alcohol, 2>% pints. Water, 4 pints. Mix the Flavoring with the Alcohol. Rub the Carbonate of Magnesium through a wire sieve to a powder, and mix with the water; then gradually add the mixture of Magnesium and water to the solution of flavoring, and after standing a day or two ior longer), with occasional agitation, pour off the clear liquid, pour the precipitate into a paper filter, and filter the poured-off liquid through the precipitate until perfectly clear. ( )ne ounce of the Soluble Flavoring added to a pint of any elixir or syrup base gives the required flavoring. This is added to elixirs requiring percolation, after the per- colation is completed, and to syrups, solutions, etc. It may also be added to any elixir in which a stronger flavor may be desired, and is useful for flavoring man)- medicinal preparations. 511. Elixir Percolating Menstruum. In former editions of Fenner's Formi lary this was called "Percolating Menstruum." A.l< "\\<>\ 38 ll. ounces. Water 72 fl. ounces. •278 ELIXIRIA — ELIXIRS. Mix them. The proportion of Alcohol and Water used is the same as is in the Elixir, and after the other ingredients, as Sugar and Soluble Flavoring, are added, it is the same as the Elixir. This Elixir Percolating Menstruum is used as a percolate whenever it is necessary to obtain the strength of drugs by percolation in making elixirs. The sense of this will be appar- ent when it is considered that the sugar contained in the elixir would be a hindrance to percolation, and that the flavoring ingredients used would lose much of their strength during the process and exposure of percolation. In making an elixir, therefore, requiring percolation, the drugs are first percolated with the percolating menstruum, the percolate filtered if neces- sary, and then the sugar dissolved in the filtrate, and the solu- ble flavoring added, which completes the elixir. 512. Elixirs Requiring Percolation. When it is required to make an Elixir in which the strength of the drugs is obtained by percolation, the process of water- bath percolation is recommended, but ordinary percolation may be employed instead, if more expedient. The following is the process : The drug or drugs, as stated in the formula. Elixir Percolating Menstruum, sufficient. Moisten the drugs with the Elixir Percolating Menstruum, and after standing a few hours in a covered vessel transfer them to the water-bath percolator, pack moderately, pour enough of the percolating menstruum upon them to cover them well, and set in a warm place for 24 hours ; then heat moderately, and after one hour begin to percolate, adding the percolating menstruum to the drugs in the percolator, and continuing the percolation until 13 fl. ounces of percolate is obtained for each pint (16 fl. ounces) of the finished Elixir required. This is then to be filtered if necessary, and to complete the Elixir take for each pint : The Percolate, as above, 13 fl. ounces. Sugar, 5 ounces av. Soluble Flavoring (510), 1 fl. ounce. ELIXIRIA — ELIXIRS. 279 Mix them and dissolve the sugar by agitation. Should it be required to remove the tannin, or otherwise treat or manipu- late the percolate for any purpose, it should be done before the sugar and flavoring are added. If small quantities only of Elixirs are required to be made, when the quantity of drugs used would be quite small, they may best be made by macerating the drugs with elixir, instead of by percolation, or, perhaps, better yet, by using fluid extracts of the drugs instead of the drugs themselves. The following is the method of procedure when fluid extracts are used : 513. Elixirs made with Fluid Extracts. If it is desired to use Fluid Extracts of the drugs, instead of the drugs themselves, as directed in the formula, take of Fluid Extracts of the drugs, the same fluid measure as is directed of weight. Elixir sufficient to make the required measure, as is stated in the formula. Mix and filter. Carbonate of Magnesium is frequently added to make them filter clear. The Elixir in this case is used instead of the Elixir Perco- lating Menstruum, Soluble Flavoring and Sugar. With Fluid Extracts, which precipitate badly when added to the Elixir, it is best to mix them with the Percolating Menstruum and filter, then add the flavoring and sugar, the same as is directed in the formula. 514. Elixirs with Salts in Solution. Some of the more soluble salts dissolve readily in the Elixirs, and others require to be dissolved separately before adding to them. Among the Solutions will be found for- mula- for making solutions convenient for combining with Elixirs, etc. They arc referred to in the formula' in which they can be advantageously used. 280 ELIXIRIA- 515. Detannating Elixirs. It is necessary in making some Elixirs and other preparations from substances containing tannin or astringent principles, to remove these principles in order that the preparations may be combined with salts of iron or other substances which would be otherwise precipitated. This may be accomplished by adding to the Elixirs any substance which will combine with the astringent principles and form precipitates which may be removed by filtration. Albumen, gelatin, and freshly precipi- tated ferric hydrate are the best adapted for that purpose, as they readily form precipitates with vegetable astringents. We have generally chosen albumen (white of egg) as being most convenient for the purpose, and have so directed in most of the formulas ; but it is sometimes more expedient to use ferric hydrate, especially in preparations containing a large amount of astringent. To detannate with this it is necessary to make a freshly precipitated ferric hydrate as is directed (see Ferri Oxidum Hydratum), and mix more or less of it, as may be required, with the Elixir or other preparation to be detan- nated, and after standing a day or two with occasional agita- tion, filtering through calico. The filtered liquid is then to be tested with tincture of iron, and if tannin still remains in solution (as is shown by an inky color when it is added), more of the ferric hydrate must be added and the Elixir treated as before. This process is tedious, but thorough, and is preferred by some to any other, but in our experience albumen is suffi- cient for most purposes and is much to be preferred in the way of convenience. 516. Elixir. Simple Elixir. The simple base which is used for making Elixirs, the same as water is used for dissolving salts, or diluted alcohol for making tinctures, is variously called Elixir, Simple Elixir, Aromatic Elixir, Cordial Elixir, Curacoa Cordial Elixir Adju- vans, etc. This base will be designated in the formulae which follow simply as Elixir. In making Elixir, only the best material should be used, the ELIXIRIA — ELIXIRS. 281 Elixir Flavoring must be good, deodorized Alcohol or Cologne Spirit should be used ; granulated Sugar is the best and most convenient, as it may readily be poured into a bottle. The following is the formula : Elixir Flavoring (508), 1 fl. ounce. Deodorized Alcohol (Cologne Spirit), . 38 fl. ounces. Water, 4^ pints, or 72 fl. ounces. Sugar, 2^< pounds, or 40 ounces av. Carbonate of Magnesium y 2 ounce av. Mix 2 ounces of the Alcohol with the Elixir Flavoring. Rub the Magnesium Carbonate through a wire sieve to reduce it to a powder, then transfer it to a mortar that will hold at least two pints, add the mixture of Flavoring and Alcohol, and rub them well together. Mix the remaining 36 ounces of Alcohol with the Water, triturate two pints of the mixture with the contents of the mortar, and filter the mixture into the remaining mixture of Alcohol and Water, then dissolve the Sugar in the filtrate by agitation, and filter the whole Elixir through the same filter to make it bright and clear. If it is desired to increase the strength of flavor of the Elixir, a larger quantity of the Elixir Flavoring and a corresponding quantity of Carbonate of Magnesium may be used. In making larger quantities of Elixir, as, say, 5 gallons or more, it is more conveniently made by adding the Elixir Flav- oring to the entire quantity of Alcohol used ; then, having mixed the powdered Carbonate Magnesium with the entire quantity of Water, gradually add the latter to the former with agitation, and let them remain for several days, with frequent agitation, before filtering; the liquid may then be filtered off and the Sugar dissolved in the filtrate. In this way any quan- tity of the Elixir may be made with but little trouble. The Elixir as thus prepared is used as a solvent for various salts, and a vehicle for various solutions and other forms of medicine. It may also In- \\>n\ to percolate, but when perco lation is required it is best accomplished as directed (512). Many Elixir formulas have been proposed and published, but in an extensive experience in making Elixirs tin- writer has found no other equal in all respects and for all purposes to the foregoing. 282 ELIXIRIA — ELIXIRS. 517. Elixir Acetate of Potassium. Acetate of Potassium, 1280 grains. Elixir, sufficient to make 1 pint. Mix and dissolve. A fl. drachm contains 10 grains of the salt. The dose is from 1 to 3 teaspoonfuls. 518. Elixir Aconite. Tincture Aconite Root, 256 minims. Elixir, sufficient to make 1 pint. Mix them. A fl. drachm contains 2 minims of the tincture. The dose is from y 2 to a teaspoonful. This is a very safe and convenient preparation, as the dose of aconite can be regu- lated as desired. 519. Elixir Adjuvans. Many Elixirs are known by this name. Simple Elixir is usually dispensed when Elixir Adjuvans is prescribed, unless some other preparation is known to be intended. In some localities an Adjuvant Elixir is much employed as a vehicle for Quinine, for this purpose the following is considerably used : Orange Peel, fresh, cut fine, .... 8 ounces av. Coriander Seed, crushed, 2 ounces av. Caraway Seed, crushed, I ounce av. Cardamom Seed, crushed, 8 ounces av. Wild Cherry Bark, crushed, ... 8 ounces av. Liquorice Root, crushed, 8 ounces av. Sugar, 32 ounces av. Alcohol, 2 pints. Water, sufficient to make 1 gallon. Mix the drugs and pour the Alcohol upon them, allow to stand for 24 hours, then add 2 pints of Water, macerate for 24 hours longer, then transfer to a percolator, add two pints of Water to the drugs and percolate, adding Water through the percolator until 7 pints of tincture are obtained ; filter and dissolve the Sugar in the filtrate. This may be made more rapidly by water-bath percolation. ELIXIRIA — ELIXIRS. 283 A similar preparation is put up by some manufacturers under the names Elixir Liquorice Compound, Elixir Wild Cherry Compound, Quinine Elixir, etc. It is chiefly used as an addition to other preparations, or a vehicle for bitter medicines. Owing to the Tannin contained in the Wild Cherry it renders Quinine insoluble, thus masking its bitter taste. 520. Elixir Anise. Anise Seed Cordial. This may be made by percolation or maceration. Anise Seed, in fine powder, 1 ounce. Elixir, sufficient to make 1 pint. Percolate or macerate and filter. Or from the Oils, as directed in the New-York and Brooklyn Formulary: Oil of Anise, Saxony, 25 minims. Oil of Fennel Seed (" Sweet "), ... 5 minims. Oil of Bitter Almonds, 1 drop. Deodorized Alcohol, . 4 fl. ounces. Syrup 10 fl. ounces. Water, 2 fl. ounces. Phosphate of Calcium, 120 grains. Mix the Oils with the Deodorized Alcohol, add the Syrup and Water, and set aside for 12 hours; then mix with the Phosphate of Calcium and filter clear. This Elixir is used as an aromatic vehicle, or addition to medicines, especially for children. 521. Elixir Antifebrin. Antifebrin, 128 grains. Elixir, sufficient to make 1 pint. Dissolve the Antifebrin by rubbing in a mortar with the Elixir. A fluiddrachm contains 1 grain of the salt. The dose is a teaspoonful t<> a tablespoonful, or more. 284 522. Elixir Antipyrin. Antipyrin, 640 grains. Elixir, sufficient to make I pint. Dissolve the Antipyrin in the Elixir by rubbing- them to- gether in a mortar. A fluiddrachm contains 5 grains of the salt. The dose is a teaspoonful or more. 523. Elixir Aromatic. Several Elixirs are known by the name of Aromatic Elixir; in fact, it is a general name for Elixirs as a class, some manu- facturers calling their Elixirs Aromatic Elixirs; but the name is applied in pharmacy generally to the Simple or Aromatic Elixir prepared from substances, instead of from their oils. The following formula may be used : Orange Peel, fresh, cut fine, .... 4 ounces aw Lemon Peel, fresh, cut fine 1 ounce av. Coriander Seed, in fine powder, 1 ounce av. Caraway Seed, in fine powder, . . . 1 ounce av. Anise Seed, in fine powder, . . . . 1 ounce av. Cinnamon Bark (Saigon), in fine powder, 1 ounce av. Sugar, 2}4 pounds av. Alcohol, 2]/ 2 pints. Water, sufficient to make 1 gallon. Macerate the drugs for 48 hours with the Alcohol, then add 4 pints of Water, and continue the maceration for 48 hours longer, pour off the liquid, transfer the drugs to a percolator, and percolate with the poured-off tincture until it has all passed, then add Water through the percolator to make the measure 6)/ 2 pints ; filter clear through a little Carbonate of Magnesium, and dissolve the Sugar in the filtrate, adding Water if necessary to make a gallon. This Elixir is used the same as Simple Elixir as a base for other Elixirs, and a vehicle for medicines, etc., but it is inad- missible for making Elixirs containing iron, bismuth, and other salts which are changed or precipitated by astringent principles. ELIXIRIA — ELIXIRS. 2S6 524. Elixir Arsenic. Elixir Arseniate of Potassium. Fowler's Solution of Arsenic, .... 640 minims. Elixir, sufficient to make 1 pint. Mix them. A fl. drachm contains 5 minims of Fowler's Solution. Dose, a teaspoonful. This is a safe and convenient preparation, the dose of Arsenic being regulated as desired without danger. The combinations of Arsenic and Quinine will be found under Quinine Elixirs. 525. Elixir Arsenic and Iodide of Mercury. Donovan's Solution of Arsenic and Iodide of Mercury, 640 minims. Elixir, sufficient to make 1 pint. Mix them. A fl. drachm contains 5 minims Donovan's Solution. Dose, a teaspoonful. 526. Elixir Arsenic and Strychnine. Sulphate of Strychnine 2 grains. Elixir Arsenic ( 524), 1 pint. Dissolve the Strychnine by rubbing with the Elixir in a mortar, or add 2 drachms of Solution of Strychnine to a pint of the Elixir of Arsenic and filter. A fl. drachm contains 5 minims of Fowler's Solution and (; 1 4 grain Strychnine Sulphate. 527. Elixir Asafetida. Tincture of Asafetida, 2 fl. ounces. Spirit of Peppermint, )/> fl. ounce. Carbonate of Magnesium, .... J^ ounce av. Sugar, 5 ounce's av. Alcohol 4 fl. ounces. Water 8 fl.ounces. Soluble Elixir Flavoring 1 fl. ounce. Kul) the Magnesium Carbonate to a fine powder in a mortar, mix the Tincture, Spirit and Alcohol, and rub with 286 ELIXIRIA — ELIXIRS. the Magnesium Carbonate, then add the Water, filter, dissolve the Sugar in the filtrate, and add the Soluble Flavoring. This Elixir is of the same strength as Syrup Asafetida, and is as agreeable a form to exhibit this disagreeable drug as can be devised, except in pills. A fl. drachm contains about 2 grains Asafetida. It is given to children and adults in doses of 1 or 2 teaspoonfuls. 528. Elixir Atropine. Sulphate of Atropine, 2 grains. Elixir, 1 pint. Dissolve the Salt by rubbing in a mortar with separate por- tions of the Elixir, and filter if necessary. A fl. drachm con- tains ^ grain of Sulphate of Atropine. For internal use this is a safe and reliable preparation. It maybe given in doses of from 10 to 20 minims. 529. Elixir Beef. Liebig's Extract of Meat, 1 ounce av. Citric Acid, 5 grains. Elixir, sufficient to make 1 pint. Rub the Extract with the Elixir in a mortar, add the Citric Acid, and after standing for some time filter. As each ounce of Liebig's Extract of Meat represents the soluble constituents of 32 ounces of fresh beef, a tablespoonful {y 2 fl. ounce) of the Elixir represents one ounce of fresh beef. The dose is from a dessert to a tablespoonful or more. Many manufacturers make the preparations of Beef with only y 2 ounce of Beef Extract in a pint. 530. Elixir Beef and Iron. Citrate of Iron and Ammonium, ... 64 grains. Elixir Beef I 529), 1 pint. Dissolve the Iron by rubbing with separate portions of the Elixir, and filter if necessary ; or add to the Elixir an equiv- alent quantity of Solution Citrate of Iron and Ammonium. Half a fl.ounce (a tablespoonful) of this Elixir represents one ELIXIRIA — ELIXIRS. 287 ounce of fresh beef and two grains of Soluble Citrate of Iron. The dose is from a dessert to a tablespoonful or more. This Elixir is preferable in many respects to Wine of Beef and Iron, for the reason that it is much more uniform, and will not pre- cipitate as the wine is liable to do. 531. Elixir Beef, Iron and Cinchona. Sulphate of Quinine, 5 grains. Sulphate of Cinchonidine, 10 grains. Citrate of Iron and Ammonium, ... 64 grains. Elixir Beef (529), 1 pint. Rub the salts with separate portions of the Elixir until dis- solved, and filter if necessary. Half a fl. ounce (a tablespoonful) represents one ounce of fresh beef, and the more important alkaloidal salts of about 8 grains of Cinchona, with 2 grains of Soluble Citrate of Iron. The dose is from a teaspoonful to a tablespoonful. This is preferable to the Wine of Beef, Iron and Cinchona, for the same reasons as above stated. 532. Elixir Belladonna. Belladonna Leaves, in coarse powder, . 256 grains. Elixir, sufficient to make 1 pint. Macerate the powder with the Elixir as directed (512) and filter. A fl. drachm represents 2 grains of Belladonna Leaves. The is from 20 to 60 minims, or more. This is a very con- venient preparation, as the dose of Belladonna can be better regulated than in the stronger preparations. 533. Elixir Berberine. Berberine Sulphate, or Hydrochlorate, . 64 grains. .Alcohol 2 11. ounces. Elixir 14 ll. ounces. Dissolve the Berberine salt first in the Alcohol by gentli heal of water-bath, then add the Elixir. 288 ELIXIRIA — ELIXIRS. A fl. drachm contains l / 2 grain of the salt. The dose is from i to 2 teaspoonfuls. The Berberine salts were formerly known by the name of Hydrastin, as Muriate of Hydrastin, etc. 534. Elixir Berberine and Iron. Pyrophosphate of Iron 64 grains. Hot Water, 1 fl. ounce. Elixir Berberine, 15 fl. ounces. Dissolve the Iron in the Hot Water and add the Elixir to the solution. A fl. drachm contains about y 2 grain each of Iron and Ber- berine. Dose, 1 to 2 teaspoonfuls. 535. Elixir Berberine, Bismuth and Iron. Citrate of Bismuth and Ammonium, . . 64 grains. Elixir Berberine and Iron (534), .... 1 pint. Rub the Bismuth salt with the Elixir, add a few drops of Water of Ammonia to dissolve, and after standing filter. A fl. drachm contains y 2 grain each of Bismuth, Iron and Berberine. Dose, 1 to 2 teaspoonfuls. 536. Elixir Bismuth. Citrate of Bismuth and Ammonium, . . 256 grains. Elixir, sufficient to make 1 pint. Water of Ammonia, a sufficient quantity. Rub the Bismuth salt with two ounces of the Elixir in a mortar, and gradually add Water of Ammonia drop by drop until the turbid solution becomes clear, or nearly clear, then add the remainder of the Elixir, and after standing a few hours filter. The Water of Ammonia is added to dissolve the Insoluble Citrate of Bismuth that may be present in the com- pound salt. This depends much upon the age and exposure of the salt, as it loses Ammonia when exposed. An equivalent quantity of Solution of Bismuth may be used, instead of the ELIXIRIA — ELIXIRS. 289 salt. A fl. drachm contains 2 grains of Soluble Citrate of Bismuth. The dose is I or 2 teaspoonfuls. 537. Elixir Bismuth and Iron. Citrate of Iron and Ammonium, . . . 12S grains. Elixir Bismuth (536), 1 pint. Rub the Iron Salt with separate portions of the Elixir to dissolve. A fl. drachm contains 2 grains Soluble Citrate of Bismuth and 1 grain Soluble Citrate of Iron. Dose, 1 or 2 teaspoonfuls. 538. Elixir Bismuth, Iron and Strychnine. Sulphate of Strychnine, 1 grain. Citrate of Iron and Ammonium 128 grains. Elixir of Bismuth (536) 8 fl. ounces. Elixir, 8 fl. ounces. Rub the Strychnine salt and Iron salt with separate por- tions of Elixir until dissolved ; then add the Elixir Bismuth, and, after standing, filter. A fl. drachm contains -, 1 - s - grain Strychnine and 1 grain each Soluble Citrates of Bismuth and Iron. The dose is from 1 to 2 teaspoonfuls. This may also be made by adding equivalent quantities of Solution of Strychnine Sulphate, and Iron Citrate to Elixir Bismuth, mixed with an equal quantity of Elixir. 539. Elixir Bismuth and Strychnine. Sulphate of Strychnine, 2 grains. Elixir Bismuth (536) 1 pint. Dissolve the Strychnine by rubbing with the Elixir Bismuth, or add to the Elixir Bismuth 2 fl.drachms Solution Sulphate of Strychnine, and after standing filter. A fl. drachm of this Elixir contains 2 grains of Soluble Bis- muth and ,.', -rains Sulphate of Strychnine. The dose is y, to 1 teaspoonful. 290 ELIXIRIA — ELIXIRS. 540. Elixir Bitter. Elixir A mar u 111 . The German Pharmacopoeia of 1872 gives the following formula for this Elixir: Extract of Buckbean, 2 parts. Extract of Orange Peel, 2 parts. Diluted Alcohol (G. P.) 16 parts. Peppermint Water, 16 parts. Spirit of Ether (Hoffman's Anodyne), . . 1 part. Dissolve the Extracts in the Diluted Alcohol and Pepper- mint Water, previously mixed, and add the Spirit of Ether. The dose is a teaspoonful or more. This is not properly an Elixir, as understood in American Pharmacy. The formula is different in the G. P. 1883. 541. Elixir Blackberry. Blackberry Root, in coarse powder, . 2 ounces av. Elixir Percolating Menstruum, . . . 1 pint. Sugar, 5 ounces av. Soluble Flavoring, 1 fl. ounce. Make by percolation as directed, 512. This may also be made by mixing — Fluid Extract of Blackberry, .... 2 fl. ounces. Elixir, 14 fl. ounces. And filtering. A fl. drachm contains 7 grains of Blackberry Root. The dose is from 1 to 2 teaspoonfuls. 542. Elixir Black Cohosh or Cimicifuga. Black Cohosh, in coarse powder, . . 2 ounces av. Elixir Percolating Menstruum, . . . 1 pint. Sugar, 5 ounces av. Soluble Flavoring, 1 fl. ounce. Make by percolation as directed, 512. ELIXIRIA — ELIXIRS. 291 It may also be made by mixing — Fluid Extract Black Cohosh, .... 2 fl. ounces. Elixir, 12 fl. ounces. Alcohol, 2 fl. ounces. And after standing a few days, filtering through Carbonate of Magnesium. A fl. drachm contains 7 grains of Black Cohosh. The dose is from 1 to 2 teaspoonfuls. 543. Elixir Black Cohosh Compound. Black Cohosh, in coarse powder, . . 1 ounce av. Colchicum Root, in coarse powder, . 1 ounce av. Iodide of Potassium, 256 grains. Percolating Menstruum 1 pint. Sugar, 5 ounces av. Soluble Flavoring, 1 fl. ounce. Make by percolation as directed, 512, and dissolve the Iodide in the percolate. This may also be made by mixing 1 ounce each of Fl. Ex- tracts of Black Cohosh and Colchicum with 14 ounces of Elixir, and dissolving the Iodide in the Elixir. A II. drachm contains 3^ grains each of Black Cohosh and Colchicum, and 2 grains of Iodide of Potassium. The dose is a tcaspoonful or more for rheumatism and neuralgia. 544. Elixir Bromide of Ammonium. Bromide of Ammonium, 640 grains. Elixir, sufficient to make I pint. Dissolve the salt in the Elixir and filter. A fl. drachm contains 5 grains Bromide of Ammonium. The close is from a teaspoonful to a tablcspoonful. 292 ELIXIRIA — ELIXIRS. 545. Elixir Bromide of Calcium. Bromide of Calcium 640 grains. Elixir, sufficient to make 1 pint. Dissolve the salt in the Elixir and filter. A fl. drachm contains 5 grains Bromide of Calcium. The dose is from 1 to 2 teaspoonfuls. 546. Elixir Brom-Iodide of Calcium Compound. Iodo-Bromide of Calcium Compoimd. Tilden's Solution Iodo-Bromide Calcium Compound. 2^ fl. ounces. Fluid Extract of Sarsaparilla Compound, 1 fl. ounce. Elixir, 8 fl. ounces. Syrup, sufficient to make 1 pint. Mix and filter if necessary. Tilden's Elixir Iodo-Bromide of Calcium Compound is a proprietary preparation, which has had a large sale. The Solution of Iodo-Bromide of Calcium, as it is named by Til- den & Co., is prepared from the Bittern which remains after the crystallization of salt from natural salt water springs. It contains Iodine, Bromine, Calcium, and a number of other substances in solution. As this solution cannot be econom- ically made from the substances themselves, and would be unlike the proprietary preparation with which the public is familiar, it is probably better to make the elixir when desired from Tilden's Solution, as above. This Elixir is used as an alterative, in doses of a teaspoonful or more. 547. Elixir Bromide of Iron. Bromide of Iron, 384 grains. Citrate of Potassium, 640 grains. Water, 2 fl. ounces. Elixir, sufficient to make 1 pint. ELIXIRIA — ELIXIRS. 293 Dissolve the Citrate of Potassium in 12 fl. ounces of the Elixir. Dissolve the Iron salt in 2 ounces of Water and mix the solutions, filter, and add enough Elixir if necessary to make a pint. A fl. drachm contains 3 grains of Bromide of Iron. The Citrate of Potassium is added to overcome the styptic dis- agreeable taste of the Bromide of Iron. The dose is from % to 1 teaspoonful. 548. Elixir Bromide of Morphine. Bromide of Morphine 16 grains. Elixir I pint. Dissolve the Salt in the Elixir. A fl. drachm contains ]/% grain Bromide of Morphine. The dose is a teaspoonful. 549. Elixir Bromide of Potassium. Two strengths of this Elixir are common — 5 grains and 10 grains of Bromide of Potassium in a fl. drachm. This is liable to confusion with physicians in prescribing it, and for that reason we prefer to stick to our old formula of 10 grains to a fl. drachm, which is none too strong for general use: Bromide of Potassium, 1280 grains. Elixir, sufficient to make 1 pint. Rub the Bromide to a coarse powder, and dissolve by agita- tion in the Elixir. Some druggists and manufacturers color this Elixir red with Carmine solution, and some leave it color- less. It should be kept uniform, either colored or uncolored, so that customers may not be suspicious when prescriptions are refilled. A fl. drachm contains 10 grains of the salt. The dose is from a teaspoonful to a table-spoonful. If the Elixir containing but 5 grains of the salt in a fl.drachm is desired, dilute the above with an equal measure of Elixir, or make by dissolving 640 grains of the salt in Elixir sufficient to make a pint. 294 ELIXIRIA — ELIXIRS. 550. Elixir Bromide of Potassium and Hydrate of Chloral. Elixir Bromide-Chloral. Bromide of Potassium, 2 ounces av. Hydrate of Chloral, I ounce av. Elixir, sufficient to make I pint. Dissolve the salts in the Elixir and filter. A fl. drachm contains 7 grains Bromide of Potassium and 3^ grains Hydrate of Chloral. The dose is from 1 to 2 tea- spoonfuls. The combinations of Bromide of Potassium and Hydrate of Chloral, in the form of an Elixir or Solution, have been very popular, several proprietary preparations of this kind having had a large sale as hypnotics and sedatives ; one quite popular with physicians being " Bromidia," prepared by Battle & Co., Chemists Corporation, St. Louis, Mo., which, according to their published statement, contains in each fl. drachm 15 grains of Bromide of Potassium, 15 grains Hydrate of Chloral, and l /& grain, each, extracts of Cannabis Indica and Hyoscya- mus. It is claimed that alcohol should not be used in making solutions of the salts named on account of the chemical action which takes place. 551. Elixir Bromide of Potassium Compound. Sedative Elixir. Bromide of Potassium, 640 grains. Sulphate of Morphine, 8 grains. Valerianate of Ammonium, 256 grains. Water of Ammonia, 90 minims. Syrup, 2 fl. ounces. Elixir, sufficient to make 1 pint. Dissolve the Salts in the Elixir and Syrup, add the Aqua Ammonia, and color, if desired, with a little Carmine solution and Caramel, then filter. ELIXIRIA — ELIXIRS. 295 A fl. drachm contains 5 grains Bromide of Potassium, 2 grains Valerianate of Ammonium, and Jg- grain Morphine. The dose is a teaspoonful or two. 552. Elixir Bromide of Quinine. Bromide of Quinine, 128 grains. Elixir, . I pint. Dissolve the Salt in the Elixir. A fl. drachm contains I grain Bromide of Quinine. The dose is a teaspoonful or more. 553. Elixir Bromide of Sodium. Bromide of Sodium, 1280 grains. Elixir, sufficient to make 1 pint. Dissolve the Salt in the Elixir, and filter. A fl. drachm contains 10 grains Bromide of Sodium. Dose, a teaspoonful to a tablespoonful. An Elixir containing 5 grains of the Salt in a fl. drachm may be made by diluting this one half with simple Elixir, or by dissolving 640 grains of the Salt in enough of the Elixir to make a pint. 554. Elixir Buchu. Buchu Leaves, in coarse powder, ... 4 ounces av. Elixir Percolating Menstruum, q. s., about 18 fl. ounces. Sugar, 5 ounces av. Soluble Flavoring, 1 fl. ounce. Make by percolation as directed, 512. This Elixir may be made from Fluid Extract Buchu as follows : Fluid Extract Buchu 4 fl. ounces. Carbonate of Magnesium 2 drachms. Elixir 12 fl. ounces. Rub the Fluid Extract with tin- Carbonate of Magnesium in .1 mortar, add the Elixir, ami filter, adding enough Elixir through the filter to make a pint. 296 ELIXIRIA — ELIXIRS. A fl. drachm represents 14 grains Buchu. The dose is a tea- spoonful to a tablespoonful. The New-York and Brooklyn Formulary directs Elixir Buchu to be prepared from Fluid Extract Buchu, 2 fl. ounces; Fluid Extract Triticum, 1 fl. ounce ; Tincture of Vanilla, 1 fl. drachm ; Syrup of Coffee, 6 fl. ounces; Carbonate of Magnesium, 120 grains, with simple Elixir enough to make a pint. 555. Elixir Buchu Compound. Elixir Buchu and Pareira Brava. Buchu, in coarse powder, 2 ounces av. Pareira Brava, in coarse powder, . . . 1 ounce av. Stone Root, in coarse powder, . . . . 1 ounce av. Elixir Percolating Menstruum, q. s., about 18 fl. ounces. Sugar, 5 ounces av. Soluble Flavoring, 1 fl. ounce. Make by percolation, as directed, 512. This Elixir may be made by mixing the Fluid Extracts of the drugs with Elixir, as directed, 513. A fl. drachm represents 7 grains Buchu, 3^ grains, each, Pareira Brava and Stone Root. The dose is from a teaspoon- ful to a tablespoonful. Several other preparations are furnished under the name of Elixir Buchu Compound. 556. Elixir Buchu, Juniper and Acetate of Potassium. Diuretic Elixir. Buchu, in coarse powder, 2 ounces av. Juniper Berries, crushed, 1 ounce av. Acetate of Potassium, 640 grains. Elixir Percolating Menstruum, q. s., about 18 fl. ounces. Soluble Flavoring, 1 fl. ounce. Sugar, 5 ounces av. Make by percolation, as directed, 512. This may also be made with Fluid Extracts of Buchu and Juniper mixed with Elixir, filtered through Carbonate of ELIXIRIA — ELIXIRS. 297 Magnesium and the Acetate of Potassium dissolved in the nitrate. A fl. drachm contains 7 grains Buchu, 3^ grains Juniper, and 5 grains Acetate of Potassium. The dose is from a tea- spoonful to a tablespoonful. 557. Elixir Calisaya or Cinchona. Elixirs of Calisaya or Cinchona and their compounds have been the best known and most popular of any ever brought to the notice of the public. Some manufacturers have intro- duced them as Elixir " Calisaya," while others have adopted the name " Cinchona," but the former is probably the most popular name. The Simple Elixir of Calisaya or Cinchona is much pre- scribed as a tonic, and is used as the base of Compound Elixirs of Calisaya or Cinchona. It may be made either from the bark or the alkaloidal salts. When made from the bark the Elixir must be " detannated " for combining with salts of iron ; but when made from the alkaloidal salts this is avoided, and the Elixir designed to be combined with iron is now generally made from the salts. The following are the formulas for making Elixir Calisaya: MADE FROM THE BARK, DETANNATED. Calisaya Bark, true, 8 ounces av. Orange Peel, fresh, 8 ounces av. Cinnamon Bark, "Saigon," .... ij4 ounces av. Coriander Seed, \ l / 2 ounces av. Red Rose Leaves, \ l / 2 ounces av. Nutmeg, '_. ounce av. Star Anise % ounce av. Sugar 2]. pounds av. Alcohol, deodorized 38 ll. ounces. Water, sufficient to make I gallon. Grind the Calisaya Bark, Cinnamon, Coriander, Nutmeg and Anise to a No. 50 powder, and having mixed a pint of Alcohol with half pint of Water, moisten the powder with half a pint of the mixture, and macerate in a warm place for one day, 298 ELIXI RIA — ELI X I RS. then transfer to the water-bath percolator, pack firmly, pour upon it the remainder of the menstruum, and set in a warm place for one daw Then heat very moderately, and, after one hour, begin to percolate, adding water to the drugs after the liquid has disappeared from the surface, and continuing the heat and percolation until 4 pints have passed. To this add the whites of 4 eggs, previously beaten with a portion of the percolate, and allow to stand for one day ; then filter through a muslin strainer. Chop the Orange Peel fine, reduce the Red Rose leaves to a coarse powder, and having mixed them together, put them in a close vessel with the remainder (22 fl. ounces) of the Alcohol. Macerate in a warm place, with occasional agitation, for two days, then pour off the liquid and reserve. Transfer the drugs (Orange and Rose) to a conical percolator, and percolate first with the detannated Calisaya percolate, and then with water until 5 pints have passed ; add this to the reserved portion, dissolve the sugar in the liquid, add enough water to make I gallon, and, after standing a few days, filter through a double filter paper. Although this is a little more trouble to make than many of the Elixirs, it leaves nothing to be desired for those who wish a first-class Elixir Calisaya made from the bark. This Elixir may be colored if desired with Cochineal color- ing and Caramel. When dispensed as Elixir Calisaya it is generally colored, but left plain for making compounds. This Elixir may be made from the Fluid Extract of Calisaya Bark- by mixing 1 fl. ounce with a pint of Elixir, adding the white of one egg, and after standing 24 hours, filtering. A fl. drachm represents about 4 grains of Calisaya, with aromatics. The dose is from a teaspoonful to a tablespoonful. 558. Elixir Calisaya or Cinchona. MADE FROM THE ALKALOIDAL SAETS. Sulphate of Quinine, 60 grains. Sulphate of Cinchonidine (Cinchonidia), 90 grains. Citric Acid 20 grains. Water of Ammonia, q. s., or 1 fl. drachm. Elixir, sufficient to make 1 gallon. ELIXIRIA — ELIXIRS. 299 Rub the Quinine and the Cinchonidine with half a pint of the Elixir, and the Citric Acid with another half a pint, and mix the solutions ; add to the mixture 7 pints of Elixir, and set in a warm place until the solution is clear; then add enough Water of Ammonia to neutralize the acid,* and filter. If it is desired to dispense this as Elixir Calisaya, it may be colored with Cochineal and Caramel coloring, but if for com- bining it should not be colored. This Elixir represents the more important properties of the bark in about the same proportion as contained in an average good quality of bark. The dose is from a teaspoonful to a tablespoonful. 559. Elixir Calisaya and Bismuth. Citrate of Bismuth and Ammonium, . .128 grains. Water, 1 ounce. Elixir Calisaya, . . . 15 fl. ounces. Dissolve the Bismuth in the Water by the aid of a few- drops of Water of Ammonia, add the Elixir, and filter; or add % fl. ounce Solution Citrate of Bismuth to a pint of Elixir Calisaya. A fl. drachm contains 1 grain of Bismuth combined with Elixir Calisaya. The dose is 1 or 2 teaspoonfuls. 560. Elixir Calisaya, Bismuth and Strychnine. Sulphate of Strychnine 2 grains. Elixir Calisaya and Bismuth 5 grains. Dissolve the Strychnine by rubbing with separate portions of the Elixir, or add 2 fl. drachms Solution of Strychnine to a pint of the Elixir, and filter. * Before the Water of Ammonia i :iilcli-< I the Klixir has a fluorescent or bluish appearance. Enough Ammonia should be added to remove this, but not leave any odor of Ammonia in the preparation after shaking. The quantity specified is correct if the officinal 10 per cent. Water of Ammonia is used. 300 ELIXIRIA — ELIXIRS. A fl. drachm contains I grain of Bismuth, -^ grain Strych- nine combined with Elixir Calisaya. The dose is a tea- spoonful. 561. Elixir Calisaya Ferrated. . Elixir Calisaya with Citrate of Iron. Ferrated Elixir Cinchona. Citrate of Iron and Ammonium, . . .128 grains. Elixir Calisaya (558), 1 pint. Dissolve the Iron salt by rubbing with successive portions of the Elixir, or use an equivalent quantity of Solution Citrate of Iron and Ammonium. A fl. drachm contains 1 grain of the Iron salt combined with Elixir Calisaya. The dose is from 1 to 2 teaspoonfuls or more. The Elixir of Calisaya and Citrate of Iron is of a dark wine color, similar in appearance to Wyeth's Ferrated Elixir of Cinchona. 562. Elixir Calisaya Ferrated, with Bismuth. Elixir Calisaya, Citrate of Iron and Bismuth. Ferrated Elixir Cinchona with Bismuth. Citrate of Bismuth and Ammonium, 128 grains. Citrate of Iron and Ammonium, . . 128 grains. Water, 1 ounce. Elixir Calisaya (558), 15 fl. ounces. Dissolve the Bismuth in the water by the aid of a few drops of water of Ammonia, dissolve the Iron salt in the Elixir by rubbing with successive portions of it, then add the solution of Bismuth and filter. This may be made by adding x / 2 ounce, each, solution of Citrate of Bismuth and Ammonium, and Solution of Citrate of Iron and Ammonium to 15 ounces of Elixir Calisaya. A fl. drachm contains 1 grain Bismuth and Iron salts, com- bined with Elixir Calisaya. The dose is a teaspoonful or more. ELIXIRIA — ELIXIRS. 301 563. Elixir Calisaya Ferrated, with Bismuth and Strychnine. Elixir Calisaya, Citrate of Iron, Bismuth and Strychnine. Fer- rated Elixir Cinchona with Bismuth and Strychnine. Sulphate of Strychnine, 1 grain. Citrate of Bismuth and Ammonium, . 128 grains. Citrate of Iron and Ammonium, . . 128 grains. Water, 1 fl. ounce. Elixir Calisaya (558), 15 fl. ounces. Dissolve the Strychnine salt by rubbing with separate por- tions of the Elixir, then dissolve the Iron salt in the same manner. Dissolve the Bismuth salt in the water by the aid of a few drops of Water of Ammonia, and add to the solu- tion, then after standing filter. This may also be made by adding 1 fl. drachm solution of Strychnine Sulphate to a pint Elixir Calisaya Ferrated with Bismuth, or by adding equivalent quantities of solutions of Citrate of Iron, Citrate of Bismuth and Sulphate of Strych- nine to Elixir Calisaya. A fl. drachm contains 1 grain each Iron and Bismuth, and 1 -1 28 grains of Strychnine combined with Elixir Calisaya. This is a dark wine-colored Elixir, better known, perhaps, by the name Elixir Cinchona, Iron, Bismuth and Strychnine. A light-colored Elixir is made with Pyrophosphate of Iron instead of the Citrate. (See No. 571.) 564. Elixir Calisaya Ferrated, with Strychnine. Elixir Cinchona, Iron and Strychnine. Sulphate of Strychnine, ingrain. Elixir Calisaya Ferrated, i pint. Dissolve the Strychnine by rubbing with separate portions of the Elixir, or add \)A fl.drachm of solution Sulphate of Strychnine to a pint of Ferrated Elixir Calisaya. A fl.drachm contains i grain Citrate of Iron, and , \ „ grain Strychnine combined with Elixir Calisaya. The dose is a teaspoonful or two. 302 ELIXIRIA — ELIXIRS. This is a dark wine-colored Elixir, better known by the name Elixir Cinchona, Iron and Strychnine. Light greenish- colored Elixirs of Calisaya, Iron and Strychnine are made with Phosphate of Iron (568) and Pyrophosphate of Iron (572). 565. Elixir Calisaya and Phosphate of Iron. ELIXIR CALISAYA FERRI-PHOSPHATED. Elixir Calisaya and Phosphate of Iron, Elixir Bark and Iron. Phosphate of Iron in scales (1880), . 256 grains. Water, l% fl. ounce. Elixir Calisaya (558), 14 fl. ounces. Dissolve the Phosphate of Iron in the water by the aid of heat, and add the Elixir; after standing, filter. This is a fine Elixir of Calisaya with the new Phosphate of Iron. It cannot be used for combining with Ammonio- Citrate of Bismuth, because it is an acid solution ; but for most purposes is preferable to the Elixir made with the Pyrophos- phate of Iron. A fl. drachm contains 2 grains of Phosphate of Iron com- bined with Elixir Calisaya. The dose is a teaspoonful or more. The Elixirs of Calisaya and Phosphate of Iron which are called " Ferri-phosphated " in this Formulary are of a light greenish color, similar in appearance to Caswell & Hazard's Ferro-phosphorated Elixirs of Calisaya. They are the best forms of Elixir " Bark and Iron." Elixir Calisaya and Pyrophosphate of Iron (569) is similar in appearance and properties to this. 566. Elixir Calisaya Ferri-phosphated with Pepsin. Elixir Calisaya, Iron and Pepsin. Saccharated Pepsin, 256 grains. Elixir Calisaya Ferri-phosphated (565), . 1 pint. Mix the Pepsin with the Elixir and macerate with occa- sional agitation for a few days, then filter. By warming to about 120 F., this may be made in a few hours. ELIXIRIA — ELIXIRS. 303 A fl. drachm contains 2 grains each, Phosphate of Iron and Pepsin, combined with Elixir Calisaya. Dose, a teaspoonful to a dessertspoonful. Elixir Calisaya, Iron and Pepsin may also be made by com- bining Pepsin with Elixir Calisaya Ferrated (561), or Elixir Calisaya and Pyrophosphate of Iron (569) in the same manner as above directed. 567. Elixir Calisaya Ferri-phosphated with Pepsin and Strychnine. Elixir Calisaya, Iron, Pepsin and Strychnine. Sulphate of Strychnine \]4. grain. Elixir Calisaya, Iron and Pepsin (566), . 1 pint. Dissolve the Strychnine by rubbing with separate portions of the Elixir, or add \yo fl. drachm of Solution Sulphate of Strychnine to a pint of Elixir Calisaya Iron and Pepsin. A fl. drachm contains 2 grains each, Phosphate of Iron and Pepsin, and -j/,,, grain Strychnine combined with Elixir Cali- saya. Dose, a teaspoonful to a dessertspoonful. Elixir Calisaya, Iron, Pepsin and Strychnine may also be made from Elixirs of Calisaya, Iron and Strychnine 1564 or 572) by macerating 256 grains of Pepsin in a pint as directed (566). \ 568. Elixir Calisaya Ferri-phosphated with Strychnine. Elixir Calisaya, Iron and Strychnine. Sulphate of Strychnine, .... i'.. grain. Phosphate of Iron in scales < [880), . 256 grains. Water i ' .. ll. mince. Elixir Calisaya 14 fl.ounces. Dissolve the Strychnine first in the water by the aid of heat, then add the Phosphate of Iron, a portion at a time until all is dissolved, t<> this add the Elixir Calisaya, and after standing, filter. 304 ELIXIRIA — ELIXIRS. A fl. drachm contains 2 grains Phosphate of Iron and jfa grain Sulphate of Strychnine combined with Elixir Calisaya. The dose is a teaspoonful or more. This is the best one of the Elixirs Calisaya, Iron and Strych- nine. It cannot be combined with Bismuth or other salts or solutions which are precipitated with acids. For other Elixirs Calisaya or Cinchona, Iron and Strychnine, see 564, 572. 569. Elixir Calisaya and Pyrophosphate of Iron. " Ferro-phosphorated" Elixir of Calisaya, " Ferrated Cordial Elixir." Pyrophosphate of Iron, 256 grains. Water \ l / 2 fl. ounce. Elixir Calisaya (558), 14 fl. ounces. Heat the water, and add the Iron salt, a portion at a time until all is dissolved, then add the Elixir Calisaya, and after standing, filter. Or add an equivalent quantity of solution Pyrophosphate of Iron to the Elixir Calisaya. A fl. drachm contains 2 grains of Pyrophosphate of Iron combined with Elixir Calisaya. This is similar in appearance to No. 565, but is a neutral instead of a slightly acid Elixir. It is the popular " Ferro- phosphorated Elixir of Calisaya," which has been so long and favorably known on the market. When it is desired to make a light-colored Elixir Calisaya and Iron to combine with Bismuth, this Elixir is the one to be used. 570. Elixir Calisaya, Pyrophosphate of Iron and Bismuth. Fcrro-phosphoratcd Elixir of Calisaya with Bismuth. Citrate of Bismuth and Ammonium, . 128 grains. Water, 1 fl. ounce. Elixir Calisaya and Pyrophosphate of Iron 15 fl. ounces. ELIXIRIA — ELIXIRS. 305 Dissolve the Bismuth salt in the water by the aid of a few drops of Water of Ammonia, and add the Elixir Calisaya and Iron. A fl. drachm contains I grain Bismuth and 2 grains Iron combined with Elixir Calisaya. The dose is a teaspoonful or more. This is the only light-colored Elixir of Calisaya and Iron with which Bismuth may be combined. 571. Elixir Calisaya, Pyrophosphate of Iron, Bismuth and Strychnine. Elixir Calisaya, Iron, Bismuth and Strychnine. Sulphate of Strychnine, \yi grain. Elixir Calisaya Phosphate of Iron and Bismuth, 1 pint. Rub the Strychnine with separate portions of the Elixir to dissolve, or add \ 1 /? fl. drachm Solution Sulphate of Strych- nine to a pint of the Elixir. A fl. drachm contains 2 grains Iron, 1 grain Bismuth and Too g ra ' n Strychnine, combined with Elixir Calisaya. The dose is a teaspoonful or two. 572. Elixir Calisaya, Pyrophosphate of Iron and Strychnine. Elixir ( alisaya, Iron and Strychnine, " Ferrophosphoratcd Elixir of ( 'alisaya, with Strychnine. Sulphate of Strychnine \]/> grain. Elixir ('alisaya and Pyrophosphate of Iron 1 pint. I\ul) tlu- Strychnine salt with separate portions of tin- Elixir t<> dissolve, or add ij4 fl.drachm of Solution Sulphate of Strychnine to a pint of the Elixir, and filter. A fl.drachm contains 2 grains of Iron, and , \ „ grain Strych- nine combined with Elixir Calisaya. 80(5 ELIXIRIA — ELIXIRS. 573. Elixir Calisaya, Pyrophosphate of Iron, Bismuth and Pepsin. Elixir Calisaya, Iron, Bismuth and Pepsin. Saccharated Pepsin, 256 grains. Elixir Calisaya, Pyrophosphate of Iron and Bismuth (570), 1 pint. Mix and macerate for several days with occasional agitation, then filter through cloth. A fl. drachm contains 2 grains each of Iron and Pepsin, and 1 grain of Bismuth, combined with Elixir Calisaya. The dose is a teaspoonful or two. 574. Elixir Calisaya, Pyrophosphate of Iron, Bismuth, and Strychnine with Pepsin. Elixir Calisaya, Iron, Bismuth, Strychnine and Pepsin. Saccharated Pepsin, 256 grains. Elixir Calisaya, Iron, Bismuth and Strychnine (571), 1 pint. Mix and macerate for a few days then filter through cloth. This may also be made by adding 1^ fl. drachm solution of Strychnine to a pint of Elixir Calisaya, Iron, Bismuth and Pepsin (573). A fl. drachm contains 2 grains Iron, 1 grain Bismuth, 2 grains Pepsin, and T ^y grain Strychnine, with Elixir Calisaya. Dose, a teaspoonful or two. 575. Elixir Calisaya and Pepsin. Saccharated Pepsin, 256 grains. Elixir Calisaya, I pint. Mix the Pepsin with the Elixir, macerate for a few days and filter through cloth. A fl. drachm contains 2 grains of Pepsin combined with Elixir Calisaya. The dose is a dessertspoonful or more. ELIXIRIA — ELIXIRS. 307 576. Elixir Calisaya, Bismuth and Pepsin. Citrate of Bismuth and Ammonium, . . 128 grains. Elixir Calisaya and Pepsin I pint. Dissolve the Bismuth Salt in I ounce of water, by the aid of a few drops Water of Ammonia, and add to the Elixir. A fl. drachm contains 2 grains Pepsin and 1 grain Bismuth, combined with Elixir Calisaya. 577. Elixir Calisaya with Beef Extract. Liebig's Extract of Meat, ]/ 2 ounce av. Elixir Calisaya 1 pint. Rub the Extract with the Elixir until they are uniformly mixed, macerate for a few days and filter. The dose is from a dessert to a tablespoonful. 578. Elixir Calisaya and Iron with Beef Extract. Elixir Calisaya, Beef and Iron. Liebig's Extract of Meat, ^ ounce av. Elixir Calisaya, Ferrated (561), . . . 1 pint. Rub the P^xtract with the Elixir until the)' are uniformly mixed, macerate for a few days and filter. The dose is a dessertspoonful or more. 579. Elixir Calisaya, Iron and Bismuth, with Beef Extract. Elixir Calisaya, Iron, Bismuth and Beef. Liebig's Extract of Meat ]/ 2 ounce aw Elixir Calisaya, Iron and Bismuth (562), i pint. Rub the Extract with the Elixir until they are uniformly mixed, macerate for a few days and filter. The dose is from a teaspoonful to a dessertspoonful. :>> )S ELIXIRIA — ELIXIRS. 580. Elixir Calisaya, Iron and Strychnine, with Extract of Beef. Liebig's Extract of Meat, y' 2 ounce av. Elixir Calisaya, Iron and Strychnine, . 1 pint. Rub the Extract with the Elixir until they are uniformly mixed, macerate for a few days and filter. The dose is a teaspoonful to a dessertspoonful. 581. Elixir Calisaya with Hypophosphites Compound. Hypophosphite of Calcium (Lime), . 256 grains. Hypophosphite of Sodium (Soda), . . 128 grains. Elixir Calisaya (558), 15 fl. ounces. Hypophosphorous Acid, I fl. ounce. Rub the Hypophosphites to a fine powder, then with the Elixir Calisaya, and add the Hypophosphorous Acid ; when dissolved, filter. A fl. drachm contains 3 grains Hypophosphites combined with Elixir Calisaya. The dose is a teaspoonful. 582. Elixir Calisaya with Lactopeptine. Lactopeptine, 256 grains. Elixir Calisaya I pint. Mix and macerate in a warm place for several days, then filter through cloth. A fl. drachm contains 2 grains of Lactopeptine, combined with Elixir Calisaya. Dose, a dessertspoonful. 583. Elixir Calisaya and Iron with Lacto- peptine. Lactopeptine, 256 grains. Elixir Calisaya and Iron (565), ... 1 pint. Mix and macerate in a warm place for several days, then filter through cloth. ELIXIRIA — ELIXIRS. 309 A fl. drachm contains 2 grains of Lactopeptine, 2 grains of Phosphate of Iron, combined with Elixir Calisaya. Dose, a teaspoonful to a dessertspoonful. 584. Elixir Calisaya, Iron and Bismuth, with Lactopeptine. Lactopeptine, 256 grains. Elixir Calisaya, Iron and Bismuth (570), I pint. Mix and macerate in a warm place for several days, then filter through cloth. A fl. drachm contains 2 grains Lactopeptine, 2 grains Iron and 1 grain Bismuth, combined with Elixir Calisaya. Dose, a teaspoonful to a dessertspoonful. 585. Elixir Calisaya, Iron and Strychnine, with Lactopeptine. Lactopeptine, 256 grains. Elixir Calisaya, Iron and Strychnine (568), 1 pint. Mix and macerate for several days in a warm place. A fl. drachm contains 2 grains Lactopeptine, 2 grains Iron, and - r ^- (T grain Strychnine, combined with Elixir Calisaya. The dose is from a teaspoonful to a dessertspoonful. Other combinations of Lactopeptine with Elixirs of Calisaya may be made by adding 256 grains of Lactopeptine to a pint of the combination desired. 586. Elixir Calisaya with Lactophosphate of Calcium ( Lime). Solution Lactophosphate of Calcium, . 2 fl. ounces. Elixir Calisaya (558), 14 fl. ounces. Mix them. A fl. drachm contains 1 grain Lactophosphate of Calcium, combined with Elixir Calisaya. 310 ELIXIRIA — ELIXIRS. 587. Elixir Calisaya with Lactophosphates Compound. Concentrated Solution of Phosphates, 1 fl. ounce. Lactic Acid, concentrated, . . . . 1 fl. drachm. Elixir Calisaya (558), 15 fl. ounces. Mix them. The dose is a dessertspoonful. 588. Elixir Calisaya with Phosphates Com- pound. Concentrated Solution Phosphates, . 8 fl. ounces. Red Cherry Juice, 1 pint. Elixir Calisaya, 5 pints. Syrup, 1 pint. Water, sufficient to make 1 gallon. Mix and filter. As thus prepared this very much resembles a popular pro- prietary elixir, known as " Wheeler's Elixir." If the Red Cherry Juice is not at hand, Raspberry Juice may be used in place of it, or elixir may be used and the preparations colored red and flavored with a little Essence Bitter Almond. y 2 ounce of Lactic Acid may be added if desired, which makes the com- position still more like Wheeler's. 589. Elixir Calisaya with " Protoxide " of Iron. Elixir Peruvian Bark with "Protoxide" of Iron. Solution of " Protoxide " of Iron, . . 6 fl. ounces. Syrup, 1 pint. Elixir Calisaya (558), 5 pints. Water, sufficient to make I gallon. Mix, color with Caramel coloring, and filter. This Elixir is similar in composition to " Nichols'," which is a well-known proprietary Elixir. The dose is a dessertspoonful to a tablespoonful. ELIXIRIA — ELIXIRS. 311 590. Elixir Calisaya with Tincture Chloride of Iron. Citrate of Potassium, y 2 ounce av. Tincture Chloride of Iron, 320 minims. Elixir Calisaya (558), 15 fl. ounces. Dissolve the salt in the Elixir, and add the Tincture of Iron ; filter. A fl. drachm contains about 6 drops Tincture of Chloride of Iron combined with Elixir Calisaya. The dose is a teaspoon- ful or more. Other Calisaya Compounds. The foregoing Compounds of Elixir Calisaya with other substances are those chiefly used, but a great variety of other combinations may be made, and some are called for occasion- ally. From the data given, they may be prepared without difficulty by druggists without special formulas. 591. Elixir Camphor, Mono-bromated. Mono-bromated Camphor, 128 grains. Alcohol, 1 fl. ounce. Elixir, 15 fl. ounces. Dissolve the Mono-bromated Camphor in the Alcohol, by heat of water-bath, and add the Elixir gradually to the solution. A fl. drachm contains 1 grain of the salt. The dose is from 1 to 4 teaspoonfuls. 592. Elixir Capsicum. Capsicum, in fine powder, 256 grains. Elixir, 1 pint. Macerate the Capsicum for 5 days in the Elixir, and filter. A fl. drachm represents 2 grains of Capsicum. 312 ELIXIRIA — ELIXIRS. 593. Elixir Cascara Sagrada. Cascara Cordial. Cascara Sagrada Bark 16 ounces av. Liquorice Root, 6 ounces av. Sweet Flag Root (Calamus), .... 2 ounces av. Cardamom Seed, 1 ounce av. Elixir Percolating Menstruum, q.s., about 7 pints. Sugar, 2y 2 pounds av. Soluble Flavoring, 8 fl. ounces. Reduce the drugs to a coarse powder, and make an elixir by percolation, as directed (512). The dose is from a dessertspoonful to a tablespoonful, or more. As Cascara Sagrada is very bitter, Buckthorn Bark is fre- quently substituted for it in making this elixir, although it is not so valuable a remedy. See the Standard Remedies, Buck- thorn Cordial. 594. Elixir Cathartic. Many preparations are sold and prescribed under the above title, and as the name does not indicate any particular com- position, the formulas for two of the most popular Cathartic Elixirs are given in this connection. Several others which have become popular as proprietary preparations will be found in that department, or among the Standard Remedies ; and still others which are frequently called for as Cathartic Elixirs under other headings, as Elixir Laxative, Elixir Mandrake Compound, Elixir Senna Compound, the Elixirs of Rhubarb, etc., etc. Senna, 2 ounces av. Liquorice Root, 1 ounce av. Epsom Salt, 1 ounce av Ginger, 48 grains. Coriander, 80 grains. Jalap, 160 grains. ELIXIRIA — ELIXIRS. 313 Scammony, 160 grains. Elixir Percolating Menstruum, q. s., or i pint. Sugar, , 5 ounces av. Soluble Flavoring, I fl. ounce. Reduce the drugs to a coarse powder, and make an elixir by percolation, as directed (512), then dissolve the Epsom Salt in the product. The dose is a dessert to a tablespoonful. 595. Cathartic or Laxative Elixir. Senna, in coarse powder, .... 2 ounces av. Butternut Bark, in coarse powder, . 1 ounce av. Mandrake Root, in coarse power, . y 2 ounce av. Sweet Flag Root, in coarse powder, y 2 ounce av. Rochelle Salts, 2 ounces av. Bicarbonate of Sodium, .... 60 grains. Elixir Percolating Menstruum, q. s., or 1 pint. Sugar 5 ounces av. Soluble Elixir Flavoring, .... 1 fl. ounce. Make by percolation as directed (5 12), and dissolve the salts in the Elixir. The dose is a dessertspoonful to a tablespoon- ful, or more. 596. Elixir Celery Compound. Celery seed, in fine powder 1 ounce av. Coca leaves, in coarse powder, . . . 1 ounce av. Black Haw Bark, in coarse powder, . 1 ounce av. Elixir Percolating Menstruum, q. s., or 1 pint. Sugar 5 ounces av. Soluble Elixir Flavoring i fl. ounce. Make by percolation as directed (512). A II. drachm represents about 10 grains of the drugs. The dose is 1 to 2 teaspoonfuls. This is similar to a popular proprietary preparation known as •• ( e/erina." 314 ELIXIRIA — ELIXIRS. 597. Elixir Chloral. Elixir Chloral Hydrate, or Hydrate of Chloral. Chloral (Hydrate of Chloral), in Crystals, 640 grains. Elixir, sufficient to make 1 pint. Dissolve the Chloral in the Elixir. A fl. drachm contains 5 grains of Chloral. The dose is from a teaspoonful to a tablespoonful. Elixir Butyl Chloral, or Croton Chloral may be made in the same proportion. See 622. 598. Elixir Chlorate of Potassium. Chlorate of Potassium in fine powder, 256 grains. Hot water, 2 fl. ounces. Elixir, 14 fl. ounces. Dissolve the salt in the hot water as nearly as possible, and add the Elixir. A fl. drachm contains 2 grains of Chlorate of Potassium. The dose is a teaspoonful or more. 599. Elixir Chloride of Ammonium. Elixir Muriate of Ammonia. Chloride of Ammonium in powder, . . 1280 grains. Elixir, sufficient to make 1 pint. Dissolve the salt in the Elixir and filter. A fl. drachm contains 10 grains Chloride of Ammonium. The dose is a teaspoonful or more. 600. Elixir Chloride of Iron, Tasteless. Elixir Muriate of Iron, Tasteless. Citrate of Potassium, 400 grains. Tincture Chloride of Iron, 640 minims. Elixir, sufficient to make 1 pint. Dissolve the salt in the Elixir and add the tincture. ELIXIRIA — ELIXIRS. 315 A fl.drachm contains 5 minims of Tincture Chloride of Iron, rendered tasteless by the addition of Citrate of Potassium. The dose is a teaspoonful or more. 601. Elixir Chloride of Iron and Arsenic. Solution Chloride of Arsenic, .... 640 minims. Tincture Chloride of Iron, 320 minims. Citrate of Potassium, 240 grains. Elixir, enough to make 1 pint. Dissolve the salt in the Elixir, add the Tincture of Iron, and lastly the solution. A fl.drachm contains 6 drops Tincture of Iron, and about 5^ grains Arsenic. The dose is a teaspoonful. 602. Elixir Chloroform. Chloroform, 128 minims. Alcohol, \y 2 fl. ounce. Elixir, sufficient to make .... 1 pint. A fl.drachm contains one minim of Chloroform, making a very convenient way of regulating the dose, which is from a teaspoonful to a tablespoonful. 603. Elixir Cinchonidine. Elixir CincJionidia. Sulphate of Cinchonidine, 128 grains. Elixir 1 pint. Dissolve the salt by rubbing in a mortar with separate por- tions of the Elixir. In cold weather it may be necessary t<> warm the Elixir in order to effect the solution. A fl.drachm contains one grain of the salt. The d<>^c is from a teaspoonful to a tablespoonful. 310 ELIXIRIA — ELIXIRS. 604. Elixir Cinchonidine and Iron. Citrate of Iron and Ammonium, . . . 128 grains. Elixir Cinchonidine, 1 pint. Dissolve the Iron by rubbing with the Elixir. This makes a dark wine-colored Elixir. If the light-greenish color is de- sired, use Phosphate of Iron in scales (1880) instead of the Citrate, dissolving it in a little hot water. A fl. drachm contains 1 grain Sulphate of Cinchonidine and 1 grain of the Iron salt. The dose is a teaspoonful or more. 605. Elixir Cinchonidine, Iron and Arsenic. Solution Chloride of Arsenic, . . . 640 minims. Elixir Cinchonidine and Iron, ... 1 pint. Mix them. A fl. drachm contains nearly a grain each of Cinchonidine and Iron and about ■£$ grain Arsenic. 606. Elixir Cinchonidine, Iron and Strychnine. Sulphate of Strychnine, \y 2 grain. Phosphate of Iron (1880) in scales, . . 128 grains. Sulphate of Cinchonidine, 128 grains. Water, 1 fl. ounce. Elixir, 15 fl. ounces. Dissolve the Strychnine salt in the Water by the aid of heat, and then add the Iron salt, and when dissolved add the solu- tion to the Elixir, in which the Cinchonidine has previously been dissolved. A fl. drachm contains 1 grain each of Iron and Cinchonidine and ,1-^ grain Strychnine. The dose is a teaspoonful or two. An Elixir similar to this was formerly much used as a sub- stitute for Elixir, Phosphate of Iron, Quinine and Strychnine, but as Quinine is now so cheap, its use has greatly decreased. ELIXIRIA — ELIXIRS. 317 607. Elixir Cincho-Quinine. Cincho-quinine, 128 grains. Diluted Sulphuric Acid, q. s. Elixir, 1 pint. Rub the Cincho-quinine with the Elixir, and gradually add the diluted Sulphuric Acid, a few drops at a time, until the solution is complete. A fl. drachm contains 1 grain of the salt. The dose is a teaspoonful to a tablespoonful. Elixirs may be made from most of the mixed salts of Cin- chona, which are similar to Cincho-quinine, in the same man- ner as this. 608. Elixir Citrate of Caffeine. Citrate of Caffeine, 64 grains. Elixir, 1 pint. Dissolve the salt in the Elixir. This may also be made double the strength of Citrate of Caffeine if desired. A fl. drachm made as above contains ]/ 2 grain of the Caffeine salt. The dose is a teaspoonful to a dessertspoonful. 609. Elixir Citrate of Iron. Citrate of Iron and Ammonium, . . 256 grains. Elixir, sufficient to make 1 pint. Dissolve the Iron salt by rubbing with separate portions of the Elixir, and filter. A fl. drachm contains 2 grains of soluble Citrate of Iron. The dose is from a teaspoonful to a tablespoonful. 610. Elixir Citrate of Iron and Quinine. Citrate of Iron and Quinine 256 grains. Elixir, sufficient to make 1 pint. Dissolve the salt by rubbing with separate portions of the Elixir, and filter. 318 ELIXIRIA — ELIXIRS. This may also be made by dissolving 192 grains Citrate of Iron and Ammonium and 64 grains Quinine in a pint of the Elixir. A fl. drachm contains 2 grains of the salt, representing about ]/ 2 grain Quinine. The dose is a teaspoonful or more. 611. Elixir Citrate of Iron, Quinine and Strychnine. Sulphate of Strychnine, \ x / 2 grain. Elixir Citrate of Iron and Quinine, . I pint. Dissolve the Strychnine salt by rubbing with separate por- tions of the Elixir, or add \ x / 2 fl. drachm solution of Sulphate of Strychnine. This may also be made by dissolving 256 grains of the com- pound salt Citrate of Iron, Quinine and Strychnine in a pint of Elixir. A fl. drachm contains about 1^ grain Iron, y 2 grain Quinine and y^Q- grain Strychnine. 612. Elixir Citrate of Iron and Strychnine. Sulphate of Strychnine, \y 2 grain. Citrate of Iron and Ammonium, . . 256 grains. Elixir, sufficient to make I pint. Dissolve the salts by rubbing with the Elixir. This may also be made from the compound salt Citrate of Iron and Strychnine by dissolving 256 grains in a pint of the Elixir. A fl. drachm contains 2 grains Iron and -^ grain Strychnine. The dose is a teaspoonful to a dessertspoonful. 613. Elixir Citrate of Lithium. Citrate of Lithium, 256 grains. Elixir, sufficient to make 1 pint. Dissolve the salt in the Elixir, and filter. A fl. drachm contains 2 grains Citrate of Lithium. The dose is from 1 to 2 teaspoonfuls. ELIXIRIA — ELIXIRS. 319 614. Elixir Cocaine. Hydrochlorate of Cocaine, .... 32 grains. Elixir, 1 pint. Dissolve the salt in the Elixir. A fl. drachm contains y± grain of Hydrochlorate of Cocaine. The dose is from 1 to 2 teaspoonfuls, as an anodyne and hypnotic. Hydrochlorate of Cocaine may be combined with many other Elixirs, and will be found advantageous in all the seda- tive and anodyne combinations. 615. Elixir Coffee. Roasted Java Coffee, 4 ounces av. Elixir Percolating Menstruum, q. s., or 1 pint. Sugar, 5 ounces av. Soluble Elixir Flavoring, 1 fl. ounce. Make by percolation as directed (512). A fl. drachm represents about 15 grains of Coffee. The dose is a teaspoonful to a tablespoonful or more. This Elixir is used mainly to mask the taste of disagreeable medicines, and may be combined to advantage with many bitter salts, fluid extracts, etc. 616. Elixir Colombo. Colombo, in coarse powder 2 ounces av. Elixir Percolating Menstruum, q. s., or 1 pint. Sugar 5 ounces av. Soluble Flavoring 1 fl. ounce. Make by percolation as directed (512), or it ma)- be made by rubbing 2 ounces of Fluid Extract of Colombo with 2 drachms Carbonate of Magnesium and 1 pint of Elixir, and filtering. A fl. drachm represents 7 grains Colombo. The dose is a teaspoonful or more. 3*20 F.LIXIRIA — ELIXIRS. 617. Elixir Conium and Iron. Fluid Extract of Conium 1 fl. ounce. Elixir Pyrophosphate of Iron, ... 15 fl. ounces. Mix and, after standing, filter. A fl. drachm contains about 3^ grains of Conium and 2 grains Pyrophosphate of Iron. The dose is a teaspoonful or more. 618. Elixir Corrosive Sublimate. Elixir Bichloride of Mercury. It is sometimes desirable to have a preparation of Bichloride of Mercury for internal use, and it is best exhibited for this purpose in the form of an Elixir, which may be made as follows : Bichloride of Mercury 16 grains. Elixir, 1 pint. Rub the salt with separate portions of the Elixir until dissolved. A fl. drachm contains ]/% grain Corrosive Sublimate. The dose is x / 2 to 1 teaspoonful. This is a very convenient form of preparing a solution of Bichloride of Mercury for internal use, as the dose can be easily regulated, and the metallic taste is well disguised. 619. Elixir Corydalis. Corydalis, in coarse powder, .... 2 ounces aw Elixir Percolating Menstruum, q. s., or 1 pint. Sugar - . 5 ounces av. Soluble Elixir Flavoring, 1 fl. ounce. Make by percolation as directed (512). It may also be made by mixing 2 ounces of the Fluid Extract of Corydalis with 14 ounces of Elixir. A (I. drachm represents about 7^ grains of the drug. The close is a teaspoonful or more. ELIXIRIA — ELIXIRS. 321 620. Elixir Corydalis Compound. Corydalis, ] Yellow Dock, ] of each Tag Alder, [ Figwort I I ounce av. Mandrake, J Elixir Percolating Menstruum, q. s., or 20 fl. ounces. Sugar, 5 ounces av. Soluble Elixir Flavoring, 1 fl. ounce. Make by percolation as directed (512). The dose is a teaspoonful or more as an alterative and diuretic. 621. Elixir Croton-Chloral Hydrate. Elixir Butyl-Chloral Hydrate. Butyl-Chloral Hydrate, 640 grains. Water, 4 fl. ounces. Elixir sufficient to make, 1 pint. Dissolve the salt in the water and add the Elixir. A fl. drachm contains 5 grains of Butyl or Croton-Chloral Hydrate. The dose is from 1 to 2 teaspoonfuls as a hypnotic and anodyne. 622. Elixir Cyanide of Potassium. Cyanide of Potassium, [6 grains. Elixir 1 pint. Pub the salt with the Elixir until dissolved, and filter. A fl.drachm contains ';; grain Cyanide of Potassium. Dose, X / A to 1 teaspoonful. This is a convenient and safe preparation for administering this salt internally, as is sometimes desired. 322 ELIXIRIA — ELIXIRS. 623. Elixir Damiana. Damiana Leaves 1280 grains. Elixir Percolating Menstruum, q. s., about 1 pint. Sugar 5 ounces av. Soluble Elixir Flavoring, 1 fl. ounce. Make by percolation as directed (512), or it may be made by mixing 2Vq fl. ounces of Fl. Ext. Damiana with 13^/8 fl. ounces of Elixir, and filtering. A fl. drachm represents 10 grains Damiana. The dose is from 1 to 4 teaspoonfuls as a diuretic and aphrodisiac. 624. Elixir Damiana Compound. Fluid Extract of Buchu, 1 fl. ounce. Fluid Extract of Nux Vomica 2 fl. drachms. Fluid Extract of Cubebs, 2 fl. drachms. Fluid Extract of Damiana, 1 fl. ounce. Carbonate of Magnesium, 60 grains. Elixir, 14 fl. ounces. Mix the Fluid Extracts and rub with the Carbonate of Magnesium ; then add the Elixir and filter. The dose is a teaspoonful or two, as a diuretic, etc. 625. Elixir Dandelion. Elixir of Taraxacum. Fluid Extract of Dandelion, . . . 2^ fl. ounces. Elixir, 13^ fl. ounces. Mix them. A fl. drachm represents 10 grains Dandelion Root. The dose is from a teaspoonful to a tablespoonful or more, as a laxative and tonic. 626. Elixir Dandelion Compound. Elixir Taraxacum Compound. Dandelion Root in coarse powder, . 16 ounces av. Liquorice Root, 8 ounces av. Gentian Root, 1 ounce av. ELIXIRIA — ELIXIRS. 323 Wild Cherry Bark, 2 ounces av. Bitter Orange Peel, 2 ounces av. Canada Snake Root, y 2 ounce av. Cloves in fine powder, ^ ounce av. Cinnamon, in fine powder, .... I ounce av. Coriander, in fine powder, .... 'i ounce av. Cardamom, in fine powder, .... % ounce av. Elixir Percolating Menstruum, q. s., about I gallon. Sugar, 2*/2 pounds. To make I gallon of the Elixir. Make by percolation as directed (512). This Elixir is variously prepared by different authorities, but amounts to about the same as made by any of the standard formulas. It is used chiefly as a vehicle for unpleasant medi- cines, and to mask the taste of Quinine. It is also given as a mild tonic and laxative in doses of a dessertspoonful or more. It has been a very popular Elixir. The New-York and Brooklyn Formulary makes Elixir Taraxacum Compound very sweet with syrup. 627. Elixir Dialysed Iron. Elixir Ferri Dialysati. Dialysed Iron Solution (504), .... 640 minims. Elixir, sufficient to make I pint. Mix them. A fl. drachm contains 5 minims Dialysed Iron. The dose is a teaspoonful or two. 628. Elixir Digitalis. Fluid Extract of Digitalis 256 minims. Elixir, sufficient to make 1 pint. .Mix them. A fl. drachm contains 2 minims Fluid Extract of Digitalis. The dose is a teaspoonful to a tablespoonful. 324 ELIXIRIA — ELIXIRS. 629. Elixir Ergot. Fluid Extract of Ergot, 2 l / 2 fl. ounces. Elixir, 14 fl. ounces. Mix them. This is the same strength as Wine of Ergot, and is much to be preferred to it. It may also be made by percolation from freshly powdered Ergot, but is probably fully as reliable made from a good fluid extract. The dose is a teaspoonful or more. 630. Elixir Erythroxylon. Elixir of Coca. Coca Leaves, in coarse powder, . . . 1280 grains. Elixir Percolating Menstruum, q. s., about 1 pint. Sugar, 5 ounces av. Soluble Elixir Flavoring, 1 fl. ounce. Make by percolation as directed (512). Or it may be made by mixing 2$/% fl. ounces of Fluid Extract Erythroxylon with i; v ; :; fl. ounces of Elixir. A fl. drachm represents 10 grains Coca leaves. The dose is I to 2 fl. drachms or more, as a nerve tonic, etc. 631. Elixir Eucalyptus. Eucalyptus Leaves, in coarse powder, . 1280 grains. Alcohol, 2 fl. ounces. Elixir Percolating Menstruum, q. s., about 14 fl. ounces. Sugar, 5 ounces av. Soluble Elixir Flavoring, 1 fl. ounce. Make by percolation as directed (512). Or it may be made by mixing 2$/q fl. ounces of Fluid Extract Eucalyptus with 2 fl. ounces of Alcohol and 11^ fl. ounces of Elixir. A fl. drachm represents 10 grains Eucalyptus. The dose is a teaspoonful or more, as an aromatic stimulant. ELIXIRIA — ELIXIRS. 325 632. Elixir Eucalyptus Compound. Eucalyptus Leaves, in coarse powder, . . 2 ounces av. Liquorice Root, in coarse powder, ... 1 ounce av. Wild Cherry Bark, in coarse powder, . . 1 ounce av. Elixir Percolating Menstruum, q. s., about 18 fl. ounces. Sugar, 5 ounces av. Soluble Elixir Flavoring, 1 fl. ounce. Make by percolation as directed (512). It may also be made from the Fluid Extracts of Eucalyptus 2 ounces, Liquorice and Wild Cherry each 1 ounce, mixed with 12 ounces of Elixir, and filtered through a little carbonate of magnesium. This Elixir is used mainly as a vehicle for Quinine and other bitter medicines. Its astringent properties render the Quinine insoluble, and therefore tasteless. 633. Elixir Euonymus. Elixir of WaJioo. Fluid Extract Wahoo, 2 fl. ounces. Fluid Extract of Liquorice, .... y 2 fl. ounce. Elixir, 13*^ fl. ounces. Mix, and, after standing, filter. This may also be made by percolating 2 ounces av. of Wahoo and yi ounce of Liquorice root in coarse powder with Elixir Percolating Menstruum 1 pint, and adding Sugar 5 ounces av., and soluble Flavoring I fl. ounce, as directed (512). A fl. drachm represents about 7 grains of Wahoo. The dose is a teaspoonful or more as a bitter tonic and laxative. The New-York and Brooklyn Formulary directs Fluid Ex- tract Euonymus 2]/, fl. ounces. Syrup <>f Coffee 2 (1. ounces, Water 2 ll. ounces, Compound Elixir of Taraxacum q. s. to make 16 fl. ounces. 634. Elixir Frangula (or Buckthorn). 'flic New-York and Brooklyn Formulary gives tin- follow- ing formula under this title. It should not be mistaken for 320 ELIXIRIA — ELIXIRS. the proprietary preparation known as Buckthorn Cordial, which will be found among the Standard Remedies : Fluid Extract of Frangula (Buckthorn), 4 fl. ounces. Compound Elixir of Taraxacum, ... 4 fl. ounces. « Simple Elixir, 8 fl. ounce. Mix them. A fl. drachm represents 15 grains Frangula. The dose is a dessertspoonful or more. 635. Elixir Gelsemium. Elixir Yellow Jasmine. Fluid Extract Gelsemium, 640 minims. Alcohol 2 fl. ounces. Elixir, sufficient to make 1 pint. Mix, and, after standing, filter. A fl. drachm represents 5 grains Gelsemium. The dose is from y 2 to a teaspoonful. 636. Elixir Gentian. Gentian Root, in coarse powder, . . . 2^ ounces av. Bitter Orange Peel, in coarse powder, . . 1^ ounces av. Coriander Seed, in fine powder, . . . . 1 ounce av. Cardamom Seed, in fine powder, . . . 1 ounce av. Elixir Percolating Menstruum, q. s., about 7^ pints. Sugar, 2y 2 pounds av. Soluble Elixir Flavoring, 8 fl. ounces. To make I gallon of Elixir. Make by percolation as directed (512). Add the whites of 2 eggs, shake, allow to stand two or three days, and filter clear. This is the same strength as the old official Compound In- fusion of Gentian. The whites of eggs are added for the purpose of removing any astringent principles, so that the ELIXIRIA — ELIXIRS. 327 Elixir may be mixed with solutions of Iron. It is the base of all the Gentian Elixirs, which may be made from it by adding various salts, solutions, etc. The dose of the Simple Elixir of Gentian as a stomachic is a teaspoonful to a tablespoonful. The New-York and Brooklyn Formulary directs : Extract of Gentian, 70 grains. Aromatic Spirit 3 fl. drachms. Tincture of Vanilla, 3 fl. drachms. Syrup 1 fl.ounce. Simple Elixir, 16 fl. ounces. Dissolve the Extract in the Syrup by trituration. Add the Vanilla and Elixir. 637. Elixir Gentian and Bismuth. Citrate of Bismuth and Ammonium, . 128 grains. Elixir Gentian, 1 pint. Dissolve the Bismuth salt in a little water by the aid of a few drops of Water of Ammonia, and add to the Elixir, and filter. A fl. drachm contains 1 grain of the Bismuth salt combined with Elixir Gentian. The dose is a teaspoonful or two — an excellent stomachic. 638. Elixir Gentian and Citrate of Iron. Ferrated Elixir of Gentian. Citrate of Iron and Ammonium, . . 128 grains. Elixir ( rentian, i pint. Dissolve the Iron salt by rubbing with separate portions of the Elixir, and filter. A fl.drachm contains 1 grain of Citrate of Iron combined with Elixir Gentian. The dose is a teaspoonful or two. 328 ELIXIRIA — ELIXIRS. 639. Elixir Gentian, Iron and Bismuth. Citrate of Bismuth and Ammonium, . 128 grains. Elixir Gentian and Citrate of Iron (638), 1 pint. Dissolve the Bismuth salt in a little water by the aid of a few drops Water of Ammonia, and add to the Elixir Gentian and Iron. A fl. drachm contains 1 grain each Iron and Bismuth com- bined with Elixir of Gentian. The dose is a teaspoonful or two. 640. Elixir Gentian, Iron and Strychnine. Sulphate of Strychnine, ij4 grain. Elixir Gentian and Iron (made with either the Citrate, Phosphate, or Pyro- phosphate of Iron), 1 pint. Dissolve the Strychnine by rubbing with separate portions of the Elixir, or add an equivalent quantity of solution of Strych- nine, and filter. A fl. drachm contains y^ grain Strychnine combined with Elixir Gentian and Iron. The dose is a teaspoonful or two. 641. Elixir Gentian, Iron, Bismuth and Strychnine. Sulphate of Strychnine, 1^ grain. Elixir Gentian, Iron and Bismuth (639), I pint. Dissolve the Strychnine by rubbing with separate portions of the Elixir, or add an equivalent quantity of solution of Strychnine, and filter. A fl. drachm contains I grain each Iron and Bismuth and y^-0- grain Strychnine combined with Elixir Gentian. The dose is a teaspoonful or two. ELIXIRIA — ELIXIRS. 329 642. Elixir Gentian and Phosphate of Iron. Ferri-phosphated Elixir of Gentian. Phosphate of Iron in scales (1880), . . 128 grains. Water, 1 fl. ounce. Elixir Gentian, 15 fl. ounces. Dissolve the Iron salt in the water by the aid of heat, add the Elixir, and filter. A fl. drachm contains 1 grain Phosphate of Iron combined with Elixir of Gentian. The dose is a teaspoonful or two. 643. Elixir Gentian, Phosphate of Iron and Strychnine. Ferri-phosphated Elixir of Gentian with Strychnine. Sulphate of Strychnine, \ l /> grain. Elixir Gentian and Phosphate of Iron, 1 pint. Dissolve the Strychnine salt by rubbing with the Elixir, or add an equivalent quantity of solution of Strychnine. A fl. drachm contains 1 grain of Phosphate of Iron and T fo grain of Strychnine combined with Elixir of Gentian. The dose is a teaspoonful or two. 644. Elixir Gentian and Pyrophosphate of Iron. Ferro-phosphorated Elixir of Gentian. Pyrophosphate of Iron 128 grains. Water 1 fl. ounce. Elixir Gentian, 15 fl. ounces. Dissolve the Iron salt in the water by the aid of heat, add the Elixir of Gentian, and filter. A fl.drachm contains 1 grain Pyrophosphate of Iron com- bined with Elixir Gentian. The dose is a teaspoonful <>r two. Other combinations of Gentian and Pyrophosphate of Iron may be made by adding other ingredients. IV.M) ELIXIRIA — ELIXIRS. 645. Elixir Gentian and Strychnine. Sulphate of Strychnine, \y 2 grain. Elixir Gentian, 1 pint. Dissolve the Strychnine by rubbing with separate portions of the Elixir, or add an equivalent quantity of solution of Strychnine, and filter. A fl. drachm contains y-J^ grain of Strychnine Sulphate com- bined with Elixir Gentian. The dose is a teaspoonful or more. 646. Elixir Gentian, Strychnine and Bismuth. Sulphate of Strychnine 1^2 grain. Elixir Gentian and Bismuth (637), . . 1 pint. Dissolve the Strychnine by rubbing with separate portions of the Elixir, or add an equivalent quantity of solution of Strychnine. A fl. drachm contains 1 grain Bismuth and T ^ grain Strych- nine combined with Elixir Bismuth. Dose, a teaspoonful. 647. Elixir Gentian with Tincture Chloride of Iron. Solution Chloride of Iron, \y 2 fl. drachm. Citric Acid, 120 grains. Carbonate of Sodium (Sal Soda), . . 200 grains. Elixir Gentian, sufficient to make . . 1 pint. Rub the Citric Acid to a powder and dissolve it in the Elixir of Gentian ; add to the solution the Carbonate of Sodium in crystals, and allow to stand until effervescence ceases and the Carbonate of Sodium is dissolved ; then add the solution of Iron, and after standing a day or two filter. This may be made by using 6 fl. drachms Tincture of Chlo- ride of Iron instead of the solution as directed. It may also be made by taking Tasteless Tincture Chloride of Iron, . §20 minims. Elixir, sufficient to make I pint. Mix them. ELIXIRIA — ELIXIRS. 331 In former editions of FENNER'S FORMULARY the formula has been — Citrate of Potassium or Sodium, . . y 2 ounce av. Tincture Chloride of Iron, 320 minims. Elixir Gentian, sufficient to make . . 1 pint. Mix and dissolve. All these formulae make, practically, the same preparation ; the Citrate of Potassium or Sodium which is formed making with the Solution of Iron double salts — Citro-Chloride of Iron and Sodium, or Citro-Chloride of Iron and Potassium — which have not the styptic taste of the iron salt. A fl. drachm contains the equivalent of 2j^ minims (6 drops) of Tincture of Iron combined with Elixir of Gentian. The dose is a teaspoonful to a dessertspoonful. 648. Elixir Gentian and Chloride of Iron with Quinine. Sulphate of Quinine, 128 grains. Elixir Gentian and Tincture of Iron, . 1 pint. Dissolve the Quinine salt in the Elixir. A fl. drachm contains 1 grain Sulphate of Quinine combined with Elixir Gentian and Chloride of Iron. The dose is a teaspoonful to a dessertspoonful. 649. Elixir Gentian, Chloride of Iron, Quinine and Strychnine. Elixir of Gentian and Chloride of Iron, . 1 pint. Sulphate of Strychnine, \]4. grain. Sulphate of Quinine 128 grains. Rub the Strychnine first with separate portions of the Elixir to dissolve, then add the Quinine salt. A fl. drachm contains i grain Sulphate of Quinine, ,,',,, grain Sulphate <>f Strychnine, combined with Elixir Gentian and Chloride of Iron. The dose is a teaspoonful or two. ELIXIRIA— ELIXIRS. 650. Elixir Gentian and Tincture Chlor- ide of Iron with Lactopeptine. Lactopeptine 256 grains. Elixir Gentian and Chloride of Iron, . . 1 pint. Macerate the Lactopeptine for 24 hours or longer, with occasional agitation, in the Elixir Gentian, etc., and filter. A fl. drachm contains 2 grains Lactopeptine combined with Elixir Gentian and Chloride of Iron. Other combinations of Lactopeptine with Elixirs of Gentian may be made in the same manner. 651. Elixir Ginger. Soluble Extract of Ginger, .... 2 fl. ounces. Elixir, 14 fl. ounces. Mix them. A fl. drachm represents about 4 grains of Ginger. The dose is a teaspoonful or more. 652. Elixir Grindelia Robusta. Fluid Extract Grindelia Robusta, . . 2^/q fl. ounces. Alcohol 2 fl. ounces. Elixir, sufficient to make 1 pint. Carbonate of Magnesium, 2 drachms. Rub the Carbonate of Magnesium to a fine powder, and then with the fluid extract and alcohol ; then gradually add Elixir and, after standing a day or two, filter. A fl. drachm represents 10 grains of Grindelia. The dose is a teaspoonful to a dessertspoonful. The New-York and Brooklyn Formulary directs only 1 ounce of the fluid extract in a pint. 653. Elixir Guarana. Fluid Extract of Guarana, 2$/& fl. ounces. Elixir, sufficient to make 1 pint. Mix them. ELIXIRIA — ELIXIRS. 333 A fl. drachm represents 10 grains Guarana. The dose is from a teaspoonful to a dessertspoonful or more. Some formulas for Elixir Guarana direct 4 fl. ounces in a pint. The New-York and Brooklyn Formulary directs Fluid Extract Guarana 3 fl. ounces, Elixir 3 fl. ounces, Compound Elixir Taraxacum 10 fl. ounces. The quantity directed in our formula — 10 grains in a fl. drachm — is the most convenient. 654. Elixir Guarana and Celery. Fluid Extract Guarana, 2 fl. ounces. Fluid Extract Celery, 2 fl. ounces. Elixir, 12 fl. ounces. Mix them and filter. A fl. drachm represents about 7 grains each of Celery and Guarana. The dose is a teaspoonful or more. 655. Elixir Helonias Compound. Mitchella (Partridge Berry or Squaw Vine), 2 ounces av. Cramp Bark, I ounce av. Blue Cohosh, i ounce av. Unicorn Root (Helonias), 1 ounce av. Elixir Percolating Menstruum, q. s., about 20 fl. ounces. Sugar, 5 ounces av. Soluble Elixir Flavoring, I fl. ounce. Make by percolation as directed (512). The dose is a tea- spoonful or more, as a catholicon. 656. Elixir Hops, or Humulus. Hops, in coarse powder, 2->a ounces av. Elixir Percolating Menstruum, q. s., about iS fl. ounces. Sugar, 5 ounces av. Soluble Elixir Flavoring, i fl. ounce. Make by percolation as directed (512). 334 ELIXIKIA — ELIXIRS. This may also be made from Fluid Extract of Hops 2^i fl. ounces, Elixir 14 fl. ounces, Carbonate of Magnesium 1 drachm. Mix and filter. A fl. drachm represents 10 grains of Hops. The dose is a teaspoonful to a tablespoonful, as a nervine and tonic. 657. Elixir Hydrastis or Golden Seal. Fluid Extract of Golden Seal, Aqueous, . 640 grains. Elixir, sufficient to make 1 pint. Mix, and, after standing, filter. This may also be made by percolating 640 grains powdered Hydrastis with Elixir sufficient to make a pint. A fl. drachm represents 5 grains Golden Seal. The dose is a teaspoonful to a dessertspoonful. 658. Elixir Hydrastis and Iron. Ferri-phosphated Elixir Hydrastis. Phosphate of Iron in scales (1880), . . 128 grains. Water, 1 fl. ounce. Elixir Hydrastis, 15 fl. ounces. Dissolve the Iron salt in the water by the aid of heat, and add to the Elixir. A fl. drachm contains 1 grain of the Iron salt combined with Elixir Hydrastis. The dose is a teaspoonful or two. Other salts of Iron may be combined with Elixir Hydrastis in a similar manner. 659. Elixir Hydrastis, Iron and Bismuth. Citrate of Bismuth and Ammonium, . 128 grains. Citrate of Iron and Ammonium, . . . 128 grains. Water, I fl. ounce. Elixir Hydrastis, 15 fl. ounces. Dissolve the Bismuth salt in the water by the aid of a few drops of Water of Ammonia ; dissolve the Iron salt in the Elixir, and mix the solutions. ELIXIRIA — ELIXIRS. 335 A fl. drachm contains I grain each of the Iron and Bismuth salts, combined with Elixir Hydrastis. The dose is a tea- spoonful or two. Elixir Hydrastis and Bismuth may be made the same as the above, only omitting the Iron salt. 660. Elixir Hydrastis, Iron and Strychnine. r * &' Sulphate of Strychnine, Elixir Hydrastis and Iron, 1 pint. Dissolve the Strychnine salt by rubbing with separate por- tions of the Elixir, or add lyt. fl. drachm solution of Strych- nine to a pint of Elixir Hydrastis and Iron. A fl. drachm contains -j-J-^ grain Strychnine and I grain Iron, combined with Elixir Hydrastis. The dose is a teaspoonful. Other combinations may readily be made by adding various salts, solutions or substances to Elixir Hydrastis, or by adding 1 ' ; fl. ounces of Aqueous Fl. Ext. Hydrastis to a pint of other Elixirs. 661. Elixir Hyoscyamus or Henbane. Fluid Extract of Hyoscyamus, .... 2^ fl. ounces. Elixir, sufficient to make I pint. Mix them. This may also be made by percolating 1280 grains Hyoscya- mus with Elixir Percolating Menstruum 1 pint, adding Sugar 5 ounces, and Soluble Flavoring 1 ounce, as directed (512). A fl. drachm represents 10 grains Hyoscyamus. The dose is a teaspoonful or more. 662. Elixir Hypophosphite of Calcium. Hypophosphite of Calcium, 256 grains. Elixir, I pint. Rub the salt to a fine powder and dissolve by rubbing with separate portions of the Elixir. A II. drachm contains 2 grains Hypophosphite of Calcium. 336 ELIXIRIA — ELIXIRS. The dose is a teaspoonful to a dessertspoonful. Elixirs of other Hypophosphites, as HypopJiospliite of Sodium, etc., may be made in the same proportion. 663. Elixir Hypophosphites Compound. Hypophosphite of Calcium, 256 grains. Hypophosphite of Sodium, 128 grains. Hypophosphite of Potassium, 64 grains. Elixir, 1 pint. Rub the Hypophosphites to a fine powder, and with the Elixir until dissolved. A fl. drachm contains 3*^ grains of the Hypophosphites. The dose is a teaspoonful or two. 664. Elixir Hypophosphite of Iron. Solution of Hypophosphite of iron, . 2 fl. ounces. Elixir 14 fl. ounces. Mix them. A fl. drachm contains 1 grain Hypophosphite of Iron. The dose is a teaspoonful. 665. Elixir Ignatia. Fluid Extract Ignatia, 1 fl. ounce. Elixir, 15 fl. ounces. Mix them and filter. A fl. drachm represents 3^ grains Ignatia. The dose is from 20 to 60 minims. 666. Elixir Iodide of Calcium. Iodide of Calcium, . . 128 grains. Elixir, 1 pint. Dissolve the Iodide of Calcium in the Elixir. A fl. drachm contains 1 grain of the salt. The dose is a tea- spoonful or more. ELIXIRIA — ELIXIRS. 337 667. Elixir Iodide of Iron (Tasteless). Tasteless Iodide of Iron (the salt), . . . 256 grains. Elixir, 1 pint. Dissolve the salt by rubbing with the Elixir. A fl. drachm contains 2 grains Tasteless Iodide of Iron — a salt formerly patented by J. Cruse. The dose is a teaspoonful. 668. Elixir Iodide of Potassium. Iodide of Potassium, 640 grains. Elixir, sufficient to make 1 pint. Dissolve the salt in the Elixir. A fl. drachm contains 5 grains of Iodide of Potassium. The dose is a teaspoonful or more. Elixir Iodide of Ammonium and Elixir Iodide of Sodium are made in the same manner and proportion. 669. Elixir Ipecac. Fluid Extract of Ipecac, i fl. ounce. Elixir, 15 fl. ounces. Mix and filter. This may also be made by macerating 1 ounce of powdered Ipecac in a pint of Elixir for several days, and filtering. A ll. drachm represents t ) )', grains of Ipecac. The dose as an expectorant, etc., is a teaspoonful or less ; as an emetic, a tablespoon ful or more. 670. Elixir Ipecac and Opium. Dover's Elixir. Opium, in powder, [28 grains. [pecac, in powder [28 grains. Elixir 1 pint. Macerate the powders in the Elixir, with occasional agita- tion for a week, and filter. 338 ELIXIRIA — ELIXIRS. This may also be made by taking Tincture of Opium, 2^ fl. ounces. Fluid Extract of Ipecac, 3^ A. ounce. Elixir, 13 fl. ounces. Mix, let stand, and filter. A fl. drachm of this Elixir represents 1 grain each Opium and Ipecac, and is equivalent to 10 grains Dover's Powder. Deodorized Tincture of Opium is to be preferred for making this Elixir, but is not directed, as it is not a complete repre- sentative of powdered Opium. 671. Elixir Jaborandi. Elixir Pilocarpus. Fluid Extract of Jaborandi 23^ fl. ounces. Alcohol, 2 fl. ounces. Elixir, 12 fl. ounces. Mix, and after standing filter, adding a little powdered Car- bonate Magnesium to the filter. A fl. drachm represents 10 grains of Jaborandi. The dose is a teaspoonful to a dessertspoonful. . 672. Elixir Juniper Berries. Fluid Extract of Juniper Berries, . . 23^ fl. ounces. Holland Gin 4 fl. ounces. Elixir, 10 fl. ounces. Carbonate of Magnesium, 1 drachm. Mix the liquids; rub with the Carbonate Magnesium in a mortar, and filter. A fl. drachm represents 10 grains Juniper Berries. The dose is a teaspoonful or more. 673. Elixir Kairine. Kairine, 128 grains. Elixir, 1 pint. Dissolve the salt in the Elixir. A fl. drachm contains 1 grain Kairine. The dose is a tea- spoonful or two. ELIXIRS. 674. Elixir Lactate of Iron. Solution " Protoxide of Iron," . . . 1 fl. ounce. Lactic Acid, Concentrated, .... \y 2 fl. drachm. Elixir, sufficient to make 1 pint. Mix them. A fl. drachm represents 1 grain Lacto-citrate of Iron. The dose is a teaspoonful or more. The Elixir Lactate of Iron may also be made by dissolving 128 grains Lactate of Iron in a pint of Elixir and adding i 1 /^ fl. drachm Lactic Acid. 675. Elixir Lactate of Iron and Pepsin. Pepsin, Saccharated, 256 grains. Elixir Lactate of Iron, ....... 1 pint. Macerate the Pepsin in the Elixir for several days, and strain. A fl. drachm contains 2 grains Saccharated Pepsin and 1 grain Lactate of Iron. Dose, a teaspoonful or two. 676. Elixir Lactopeptine. Lactopeptine, 384 grains. Glycerin, 2 fl. ounces. Water, 2 fl. ounces. Elixir, 12 fl. ounces. Macerate the Lactopeptine in the mixed liquids for several days in a warm place. Color with cochineal coloring and filter. A fl. drachm contains 3 grains Lactopeptine. The dose is a teaspoonful to a dessertspoonful. A great variety of combinations of Lactopeptine with other preparations may be made by macerating 256 grains Lacto- peptine in a pint of the required Elixir. The combinations of Lactopeptine with Calisaya and Gentian Elixirs will be found under those headings. 340 ELIXIRIA — ELIXIRS. 677. Elixir Lactopeptine and Bismuth. Citrate of Bismuth and Ammonium, . .128 grains. Elixir Lactopeptine (uncolored), .... I pint. Dissolve the Bismuth salt with half an ounce of water by the aid of a few drops of Water of Ammonia, and add to the Elixir. A fl. drachm contains 3 grains Lactopeptine and 1 grain of Bismuth. The dose is a teaspoonful or two. 678. Elixir Lactopeptine, Bismuth and Strychnine. Sulphate of Strychnine, 1^ grain. Elixir Lactopeptine and Bismuth, . . . 1 pint. Dissolve the Strychnine salt by rubbing with separate por- tions of the Elixir, or add an equivalent quantity of Solution of Strychnine. A fl. drachm contains 3 grains Lactopeptine, 1 grain Bismuth, and y^ grain Strychnine. The dose is a teaspoonful to a dessertspoonful. 679. Elixir Lactophosphate of Calcium (Lime). Solution Lactophosphate of Calcium, . 2 fl. ounces. Elixir, 14 fl. ounces. Mix and filter. A fl. drachm contains 2 grains Lactophosphate of Calcium. The dose is a teaspoonful or two. 680. Elixir Lactophosphate of Calcium and Iron. Solution Phosphate of Iron, .... 1 fl. ounce. Solution Lactophosphate of Calcium, 1 fl. ounce. Elixir 14 fl. ounces. Mix and filter. A fl. drachm contains 1 grain each Calcium and Iron salts in solution. Dose, a teaspoonful or more. ELIXIRIA — ELIXIRS. 341 681. Elixir Lactophosphate of Calcium with Pepsin. Pepsin, saccharated 256 grains. Elixir Lactophosphate of Calcium, . . 1 pint. Macerate the Pepsin in the Elixir for several days, and filter. A fl. drachm contains 2 grains each Lactophosphate of Lime and Pepsin. A great variety of other combinations of the Lactophos- phates with other substances may be made up in the form of Elixirs, by adding the solutions of Lactophosphates to the required Elixirs, or other substances to Elixirs of Lacto- phosphates. 682. Elixir Laxative. A number of preparations by this name have been quite popular. The following formula makes a preparation similar to the one which has been best received : Senna, in coarse powder -2 ounces av. Gentian, in coarse powder, ]/ 2 ounce av. Cardamom Seed, in fine powder, . . 1 drachm. Coriander Seed, in fine powder, ... 1 drachm. Elixir Percolating Menstruum, ... 1 pint. Sugar, 5 ounces av. Soluble Elixir Flavoring 1 ounce av. Phosphate of Iron in scales (1880), . . 12S grains. Make by percolation as directed (5 12). Detannate with ]/ 2 ounce white of egg. Dissolve the Iron salt in 1 ounce of hot water, and add to the detannated Elixir. It may also be made by adding 2 fl. ounces Fluid Extract Senna and yi fl. ounce Tincture Cardamom Seed to 14^ fl. ounces of Elixir Gentian and Phosphate of Iron. The dose is a dessertspoon- ful to a tablespoonful as a laxative and tonic. Other Laxative Elixirs are noted under the Cathartic Elixirs and among the Standard Remedies. 342 ELIXIRIA — ELIXIRS. 683. Elixir Lactucarium. Lactucarium, 256 grains. Elixir, 1 pint. Macerate the Lactucarium in the Elixir for 24 hours; then rub it to a smooth mixture with the Elixir, and after standing a day or two filter. A fl. drachm contains 2 grains of Lactucarium. The dose is a teaspoon ful or more. 684. Elixir Leptandra. Leptandra (Culver's Root), in coarse powder, . 1280 grains. Elixir Percolating Menstruum, q. s., about 1 pint. Sugar, 5 ounces av. Soluble Elixir Flavoring, 1 fl. ounce. Make by percolation as directed (512), or it may be made by mixing 2^ fl. ounces of Fluid Extract Leptandra with enough Elixir to make a pint. A fl. drachm represents 10 grains Leptandra. The dose is a teaspoonful or two. 685. Elixir Liquorice. Elixir Glycyrrhiza. Liquorice Root, in coarse powder, . . 2^ ounces av. Elixir Percolating Menstruum, q.s., about I pint. Water of Ammonia, 1 fl. drachm. Sugar, 5 ounces av. Soluble Elixir Flavoring, 1 fl. ounce. Make by percolation as directed (512), or it may be made by mixing Fluid Extract Liquorice 2% fl. ounces with Water of Ammonia, 20 minims, and Elixir 14 fl. ounces. A fl. drachm represents 10 grains of Liquorice Root. The dose is a teaspoonful or more. This Elixir is much used as a vehicle for bitter medicines, as Quinine, etc. ELIXIRIA — ELIXIRS. 343 686. Elixir Liquorice Compound. Elixir Glycyrrhisa Compound. Liquorice Root, in coarse powder, . . \% ounce av. Wild Cherry, in coarse powder, I ounce av. Cardamom Seed, in fine powder, . . I drachm. Coriander Seed, in fine powder, . . i drachm. Cinnamon, in fine powder, I drachm. Elixir Percolating Menstruum, q.s., about I pint. Water of Ammonia, I fl. drachm. Sugar, 5 ounces av. Soluble Elixir Flavoring, I fl. ounce. Make by percolation as directed (512), or add the Fluid Extract of the drugs to Elixir, as directed (513). This Elixir is used chiefly as a vehicle for Quinine and other bitter medicines. 687. Elixir Lobelia Compound. Lobelia, in coarse powder, 1 ounce av. Bloodroot, in coarse powder, . . . . 1 ounce av. Skunk Cabbage, in coarse powder, . . 1 ounce av. Elixir Percolating Menstruum, q.s., about 1 pint. Sugar, 5 ounces av. Soluble Elixir Flavoring, 1 fl. ounce. Make by percolation as directed (512), or add 1 ounce each of the Fluid Extracts of the drugs to 13 fl. ounces of Elixir. The dose is y> to 1 teaspoonful as an expectorant. 688. Elixir Lupulin. Alcohol, 4 fl. ounces. Lupulin 2.< 4 ounces av. Elixir Percolating Menstruum, q.s., about 12 fl. ounces. Sugar 5 ounces av. Soluble Elixir Flavoring 1 fl. ounce. 344 ELIXIRIA — ELIXIRS. Make by percolation as directed (512), or add 2 3^ fl. ounces of the Fluid Extract Lupulin to 14 fl. ounces Elixir, and filter through Carbonate Magnesium. A fl. drachm represents 10 grains Lupulin. The dose is a teaspoon ful. 689. Elixir Malt. Extract of Malt 4 fl. ounces. Elixir 12 fl. ounces. Mix thoroughly, and, after standing, strain or filter. The dose is a tablespoonful to a wineglassful. 690. Elixir Malt with Hypophosphites. Extract of Malt, 4 fl. ounces. Elixir Hypophosphites Compound (663), 12 fl. ounces. Mix thoroughly, and, after standing, strain or filter. The dose is a dessertspoonful. 691. Elixir Malt and Iron. Phosphate of Iron in scales (1880), . .128 grains. Water, 1 fl. ounce. Elixir Malt 15 fl. ounces. Dissolve the Iron salt in the Water by the aid of heat and add to the Elixir. A fl. drachm contains 1 grain Phosphate of Iron combined with Elixir Malt. The dose is a dessertspoonful. 692. Other Malt Elixirs. A great variety of combinations of Malt with other Elixirs may be made either by adding 4 fl. ounces of Extract of Malt to the required Elixir as directed (690), or adding the required substances to Elixir Malt, as directed (691). ELIXIRIA — ELIXIRS. 345 693. Elixir Mandrake or May Apple. Elixir Podophyllum Compound. Fluid Extract of Mandrake 2 fl. ounces. Alcohol, 2 fl. ounces. Elixir, 12 fl. ounces. Mix them, and, after standing, filter through a little Carbon- ate of Magnesium. A fl. drachm represents 7 grains Mandrake. Dose, a teaspoonful. 694. Elixir Mandrake Compound. Elixir Podophyllum Compound. Mandrake (Podophyllum), in powder, . 1 ounce av. Leptandra (Culver's Root), in powder, 1 ounce av. Senna, in coarse powder, 1 ounce av. Elixir Percolating Menstruum, q.s., about 18 fl. ounces. Sugar, 5 ounces av. Soluble Elixir Flavoring, 1 fl. ounce. Make by percolation as directed (512), or mix the Fluid Extracts of the drugs with Elixir, and filter through Carbon- ate Magnesium. A fl. drachm contains about 3^ grains each of the drugs. The dose is a teaspoonful as a cholagogue and laxative. 695. Elixir Matico Compound. Matico, in coarse powder i ounce av. Buchu, in coarse powder, 1 ounce aw Cubebs, in line powder I ounce av. Elixir Percolating Menstruum, q.s., about l S tl. ounces. Sugar 5 ounces av. Soluble Elixir Flavoring i tl. ounce. Make by percolation as directed (5 12), or by mixing the fluid extracts of the drugs with Elixir, rubbing with Carbonate 346 ELIXIRIA — ELIXIRS. of Magnesium, and filtering. The dose is a teaspoonful or more. 696. Elixir Mono-bromated Camphor Comp. Mono-bromated Camphor 16 grains. Butyl-Chloral, 24 grains. Spirit of Cinnamon \y 2 fi. ounce. Tincture of Gelsemium, 80 minims. Elixir \ l / 2 fl. ounce. Syrup, ..." 8 fl. ounces. Rub the Butyl-Chloral and Mono-bromated Camphor with the Spirit of Cinnamon ; add the Tincture of Gelsemium, then the Elixir, then the Syrup, mixing them well together. Dose, a teaspoonful. This is considerably prescribed in France. 697. Elixir Morphine. Sulphate of Morphine, 16 grains. Elixir I pint. Mix and dissolve. A fl. drachm contains l /% grain Sulphate of Morphine. The dose is a teaspoonful. This preparation is of the same strength as the Liquor Mor- pJiicc Sulphatis, formerly official, but is a better preparation, as it will keep any length of time. 698. Elixir Nux Vomica. Tincture Nux Vomica, 640 minims. Diluted Sulphuric Acid, 2 fl. drachms. Elixir, sufficient to make 1 pint. Mix, and after standing filter. A fl. drachm contains 5 minims Tincture Nux Vomica. The dose is from y 2 to a teaspoonful. ELIXIRIA — ELIXIRS. 347 699. Elixir Opium. Opium, in powder, 128 grains. Elixir, 1 pint. Rub the Opium with the Elixir, and macerate for several days, then filter. It may also be made by mixing Tincture Opium, 2y% fl. ounces. Elixir, sufficient to make I pint. An Elixir Opium Deodorized may be made in the same way from the Deodorized Tincture of Opium. A fl. drachm of Elixir Opium represents 1 grain Opium. The dose is a teaspoonful. A proprietary preparation known as McMunris Elixir of Opium is the same as Deodorized Tincture of Opium, and should not be dispensed when Elixir Opium is directed, unless it is particularly designated. 700. Elixir Orange. Elixir Aurantii. Oil of Orange, fresh, 30 minims. Alcohol, 6 fl. ounces. Water 10 fl. ounces. Sugar, 5 ounces av. Carbonate of Magnesium, 120 grains. Dissolve the Oil of Orange in the Alcohol, rub the Magne- sium Carbonate to a fine powder, and add to the Water; then gradually add the mixture of Magnesium to the Solution of Orange, and after mixing thoroughly allow to stand; then filter clear and dissolve the Sugar in the filtrate. This Elixir is known by many names, and used mostly as an adjuvant or simple Elixir. It may also be made by macerating 4 ounces of fresh Orange Peel in half a pint of Alcohol for several days, draining and pressing; then adding 8 ounces of Water and 4 ounces of Syrup, and filtering. For other Elixirs of Orange see Simple Elixir, Aromatic Elixir, Adjuvant Elixir, Curacoa Cordial, etc. 848 ELIXIRIA — ELIXIRS. 701. Elixir Orange Compound. Elixir Vicerale Hoffman n i. This Elixir was formerly official in the German Pharma- copoeia. The formula is as follows: Orange Peel, cut, . Cinnamon Carbonate of Potassium Sherry Wine, . . . Extract of Gentian, . Extract of Wormwood, Extract of Buckbean, Extract of Cascarilla, Macerate the Orange, Cinnamon and Carbonate of Potassium for 8 days in the Wine, pour off, express, and dissolve the extracts in the liquid. The dose is a teaspoonful. 50 parts or 3 ? 4 ounces. 10 parts or 6 drachms. 2% parts or 90 grains. SO parts or 19 fl. ounces. 5 parts or 3 drachms. 5 parts or 3 drachms. 5 parts or 3 drachms. 5 parts or 3 drachms. 702. Elixir Pancreatin. This Elixir may be made from the fresh Pancreas of the pig, as follows : The Pancreas of 3 pigs, chopped. Water, 6 pints. Glycerin, 20 fl. ounces. Hydrochloric Acid 2 fl. ounces. Macerate for 3 days in a cool place, then strain and add — Elixir, 3 pints. Alcohol 8 fl. ounces. Soluble Flavoring, 2 fl. ounces. After standing a few days filter. This may also be made from Pancreatin : Pancreatin, 1 ounce av. Glycerin, 4 ounces av. Elixir, sufficient to make 1 pint. ELIXIRIA — ELIXIRS. 349 Macerate the Pancreatin for 24 hours or more in the Elixir and Glycerin, and filter. The dose of Elixir Pancreatin is a dessertspoonful or more. 703. Elixir Pancreatin and Pepsin. Pancreatin, 256 grains. Pepsin, 256 grains. Glycerin, 4 ounces av. Elixir, sufficient to make 1 pint. Macerate the powders for 24 hours or longer in the Elixir and Glycerin, and filter. A fl. drachm contains 2 grains each Pacreatin and Pepsin. The dose is a dessertspoonful. 704. Elixir Pancreatin, Pepsin and Bismuth. Citrate of Bismuth and Ammonium, . 64 grains. Elixir, Pancreatin, and Pepsin, ... 1 pint. Dissolve the Bismuth salt in y> ounce of water by the aid of a few drops of Water of Ammonia, and add to the Elixir. A fl. drachm contains 2 grains each Pancreatin and Pepsin and ) j grain Bismuth. The dose is a dessertspoonful. ' )ther combinations of Pancreatin and Pepsin may be made in a similar manner. 705. Elixir Paraldehyd. Paraldehyd 640 minims. Elixir, sufficient to make 1 pint. Mix them. A fl.drachm contains 5 minims Paraldehyd. The dose is a teaspoonful to a tablespoonful as a hypnotic or anodyne. 350 ELIXIKIA — ELIXIRS. 706. Elixir Pareira Brava. Fluid Extract Pareira Brava, .... 2^ fl. ounces. Elixir, 14 fl. ounces. Mix them, and, after standing, filter through a little Carbon- ate Magnesium. It may also be made by percolating the drug with Elixir, as directed (512). A fl. drachm represents 10 grains of the drug. The dose is a teaspoonful to a dessertspoonful. 707. Elixir Pepsin. Elixir of Pepsin may be prepared from the fresh stomachs of the pig or calf, or from the saccharated Pepsins, or the Pure Pepsins which are furnished by manufacturers. Elixirs of Pepsin desired to combine with other preparations, as Bismuth, Iron, etc., should be made from the Saccharated Pepsin. Some manufacturers call Wine of Pepsin and its combinations Elixirs of Pepsin. The value of Elixirs of Pepsin and their combinations with various salts as are found on the market has been seriously questioned, and not without reason, as they present many incompatibilities; but these combinations are much used and are perhaps as valuable as many other compounds which are prescribed. Elixir Pepsin may be prepared from the fresh stomachs as follows : The stomachs of 6 pigs. Water, 6 pints. Glycerin, 20 fl. ounces. Acetic Acid, 6 fl. ounces. Dissect the lining membrane from the stomachs, and digest for three days in the mixture of the liquids, then strain and add Elixir, 3 pints. Alcohol, 8 fl. ounces. Soluble Elixir Flavoring-, 2 fl. ounces. and, after standing a few days, filt er. ELIXIRIA — ELIXIRS. 351 This may be used as a simple Elixir of Pepsin, or may be combined with salts which are not incompatible with acids ; but it forms precipitates with Bismuth and some other prep- arations. 708. Elixir Pepsin. MADE FROM SACCHARATED OR POWDERED PEPSIN. Pepsin, Saccharated or Powdered, . . .256 grains. Water, 3 fl. ounces. Glycerin, 3 fl. ounces. Elixir, 10 fl. ounces. Macerate the Pepsin in the liquids for 24 hours or longer and strain or filter through coarse filtering paper. A fl. drachm contains 2 grains of Saccharated or official Pep- sin. The dose is from a teaspoonful to a dessertspoonful or more. Elixir Pepsin may also be made from Scale Pepsin by first reducing it to a powder and macerating 64 grains in 3 ounces each Water and Glycerin and 10 ounces of Elixir. As thus prepared it is more than double the strength of Elixir Pepsin as made from Saccharated Pepsin, representing in a fl. drachm the equivalent of 5 grains Saccharated Pepsin. It may be colored with a little caramel if desired. Elixirs of Pepsin are very slow to filter because of the mucous which covers the surface of the paper. They are therefore better strained through muslin. This Elixir Pepsin should be used for combining with Bis- muth, Iron salts, etc. 709. Elixir Pepsin and Bismuth. Citrate of Bismuth and Ammonium, . . 128 grains. Elixir Pepsin (708), I pint. Dissolve the Bismuth salt in _'_• ounce of water with the aid of a few drops of Water of Ammonia, and add to the Elixir. It may be colored, if desired, with a little caramel. A fl.drachm contains i grain Bismuth combined with Elixir of Pepsin. The d<>sr is a teaspoonful to a dessertspoonful. 352 ELIXIRIA 710. Elixir Pepsin, Bismuth and Strychnine. Sulphate of Strychnine, \ J / 2 grain. Elixir Pepsin and Bismuth (709*, . . . I pint. Dissolve the Strychnine salt by rubbing with separate por- tions of the Elixir, then filter Or add \]/ 2 drachm of Solu- tion of Strychnine to a pint of Elixir Pepsin and Bismuth. A fl. drachm contains 1 grain Bismuth and T \-^ grain Strych- nine combined with Elixir Pepsin. Dose, a teaspoonful to a dessertspoonful. 711. Elixir Pepsin, Bismuth and Iron. Citrate of Iron and Ammonium 128 grains. Elixir Pepsin and Bismuth (709), .... 1 pint. Dissolve the Iron salt by rubbing with separate portions of the Elixir. This may also be made with Pyrophosphate of Iron instead of Citrate, by dissolving 128 grains of Pyrophosphate of Iron in 1 ounce hot water and adding to the Elixir. A fl. drachm contains 1 grain each Bismuth and Iron com- bined with Elixir Pepsin. The dose is a teaspoonful to a des- sertspoonful. 712. Elixir Pepsin, Bismuth, Iron and Strych- nine. Sulphate of Strychnine, \ l / 2 grain. Elixir Pepsin, Bismuth and Iron (711), . I pint. Dissolve the Strychnine salt by rubbing with separate por- tions of the Elixir, or add iyi fl. drachm of Solution of Strych- nine to a pint of the Elixir. This may also be made by dissolving 128 grains Citrate or Pyrophosphate of Iron in a pint of Elixir Pepsin, Bismuth and Strychnine. A fl. drachm contains 1 grain each Bismuth and Iron, and i 1 grain Strychnine, combined with Elixir Pepsin. The dose is a teaspoonful to a dessertspoonful. ELIXIRIA — ELIXIRS. 353 713. Elixir Pepsin and Iron. Phosphate of Iron, in scales (1880), . .128 grains. Water i fl. ounce. Elixir Pepsin, 15 fl. ounces. Dissolve the Iron salt in the Water by the aid of heat and add the Elixir. This Elixir may also be made with the same quantity of Citrate of Iron and Ammonium, or of Pyrophosphate of Iron in place of the Phosphate. A fl. drachm contains 1 grain of the Iron salt combined with Elixir Pepsin. The dose is a dessertspoonful. 714. Elixir Pepsin, Iron and Strychnine. Sulphate of Strychnine, \}i grain. Elixir Pepsin and Iron, 1 pint. Dissolve the Strychnine by rubbing with separate portions of the Elixir, or add i}4 fl. drachm Solution of Strychnine to a pint of the Elixir. A fl. drachm contains 1 grain Iron and j-J-y grain Strychnine, combined with Elixir Pepsin. The dose is a teaspoonful to a dessertspoonful. 715. Elixir Pepsin and Lactic Acid. Concentrated Lactic Acid, 64 minims. Scale Pepsin, 64 grains. Glycerin 3 fl. ounces. Water, 3 fl. ounces. Elixir 15 fl. ounces. Rub the Pepsin to a powder and add to the mi\;ed liquids, allow to stand several days, with frequent agitation, then strain through muslin. A fl.drachm contains '„■ grain pure Pepsin (equivalent to 5 grains Saccharated Pepsin) and $4 minim Lactic Acid. The dose 1- a teaspoonful to a dessertspoon fu'k 354 ELIXIRIA — ELIXIRS. This is one of the best liquid preparations of Pepsin, but is not compatible with soluble Bismuth or Pyrophosphate of Iron. It is called by some manufacturers Aromatic Solution of Pepsin, Liquor Pepsin, etc. This Elixir may also be made the same strength by taking 640 grains of Saccharated Pepsin, instead of the scale Pepsin, and it is frequently made with much less, from 2 to 3 grains of Saccharated Pepsin being used for each fl. drachm. 716. Elixir Pepsin and Quinine. Sulphate of Quinine, 128 grains. Elixir Pepsin and Lactic Acid (715), . . 1 pint. Rub the Quinine salt with the Elixir to dissolve. A fl. drachm contains 1 grain Sulphate of Quinine combined with the Pepsin Elixir. The dose is a teaspoonful. 717. Elixir Pepsin, Quinine and Iron. Phosphate of Iron, in scales (1880), . .128 grains. Water, 1 fl. ounce. Elixir Pepsin and Quinine (716), ... 15 fl. ounces. Dissolve the Iron salt in the Water by the aid of heat and add the Elixir. A fl. drachm contains 1 grain each of Iron and Quinine com- bined with Elixir Pepsin. The dose is a teaspoonful. 718. Elixir Pepsin, Quinine and Strychnine. Sulphate of Strychnine, 1% grain. Elixir Pepsin and Quinine (716), . . . 1 pint. Dissolve the Strychnine by rubbing with separate portions of the Elixir, or add \]/ 2 fl. drachm of Solution of Strychnine to a pint of the Elixir. A fl. drachm contains 1 grain Quinine and y^ grain Strych- nine combined with Elixir Pepsin. The dose is a teaspoonful. ELIXIRIA — ELIXIRS. 355 719. Elixir Pepsin, Quinine, Iron and Strych- nine. Sulphate of Strychnine, 1^ grain. Elixir Pepsin, Quinine and Iron (717), . . 1 pint. Dissolve the Strychnine salt by rubbing with separate por- tions of the Elixir, or add \y 2 fl. drachm Solution of Strychnine to a pint of the Elixir. A fl. drachm contains I grain each Quinine and Iron and y^ grain Strychnine combined with Elixir Pepsin. The dose is a teaspoonful. 720. Elixir Pepsin and Strychnine. Sulphate of Strychnine, \y 2 grain. Elixir Pepsin and Lactic Acid (715), . . 1 pint. Dissolve the Strychnine salt by rubbing with separate por- tions of the Elixir, or add l}i drachm Solution of Strychnine to a pint of the Elixir. A fl. drachm contains T -J-g- grain Strychnine combined with Elixir Pepsin. The dose is a teaspoonful to a dessertspoonful. 721. Elixir Pepsin and Wafer Ash. Elixir Pepsin and Ptelea. Fluid Extract of Wafer Ash (Ptelea), . 1 fl. ounce. Elixir Pepsin, 15 fl. ounces. Mix them and, after standing, filter clear through a little powdered charcoal. A fl. drachm represents the soluble constituents of 3^ grains Wafer Ash combined with Elixir Pepsin. The dose is a tea- spoonful to a dessertspoonful. A Glyccrite of Pepsin and Wafer Ash is also made. See Glycerites. Other Pepsin Elixirs. A great variety of other combinations of Pepsin with other substances in the form of Elixirs may be made by adding Pepsin to other Elixirs, or other substances to Elixir Pepsin. 356 ELIXIRIA — ELIXIRS. 722. Elixir Phosphate of Calcium (Lime). Solution Phosphate of Calcium, ... 2 fl. ounces. Elixir, 14 fl. ounces. Mix them. A fl. drachm contains 2 grains Phosphate of Calcium. Dose, a teaspoonful to a dessertspoonful. 723. Elixir Phosphate of Iron. Phosphate of Iron, in scales (1880), . . 256 grains. Water, ...» 2 fl. ounces. Elixir, sufficient to make 1 pint. Dissolve the Phosphate of Iron in the Water by the aid of heat and add the Elixir. A fl. drachm contains 2 grains Phosphate of Iron. Dose, a teaspoonful or more. 724. Elixir Phosphates Compound. Concentrated Solution of Phosphates Compound, 2 fl. ounces. Elixir, 15 fl. ounces. Mix them. The dose is a teaspoonful, containing about 3^ grains of the mineral Phosphates in solution, with excess of phosphoric acid. 725. Elixir Phosphate of Iron and Quinine. Phosphate of Iron, in scales (1880), . . 256 grains. Sulphate of Quinine, 128 grains. Phosphoric Acid (50 per cent.), .... 30 minims. Water, 2 fl. ounces. Glycerin, 2 fl. ounces. Elixir, 12 fl. ounces. Mix the Elixir and Acid and dissolve the Quinine salt in the mixture by the aid of gentle heat. Dissolve the Phosphate ELIXIRIA — ELIXIRS. 357 of Iron in the Water and Glycerin, by the aid of heat, and while both the solutions are still hot add the Quinine solution to the Iron solution. When cool filter. It is necessary that the solutions be quite warm, about 160 F., and that they be gradually mixed together, otherwise a gelatinous mass, instead of a clear solution, will result. The Quinine solution should be added to the Iron solution. A fl. drachm contains 2 grains Phosphate of Iron and I grain of Quinine. Dose, a teaspoonful or more. 726. Elixir Phosphate of Iron, Quinine and Strychnine. Sulphate of Strychnine, 2 grains. Elixir Phosphate of Iron and Quinine, . . 1 pint. Dissolve the Strychnine by rubbing with separate portions of the Elixir, or add 2 fl. drachms Solution of Strychnine to a pint of the Elixir. This may also be made as directed in the previous formula, by adding 2 grains of Strychnine Sulphate to the ingredients therein named and proceeding in the same manner. A fl. drachm contains 2 grains Phosphate of Iron, 1 grain Quinine, and ,./, grain of Strychnine. The proportion of Strychnine as prepared by manufacturers varies considerably, some using only -j i- - grain, while others use as much as J - grain in a fl. drachm. 727. Elixir Phosphoric Acid. Phosphoric Acid, 50 per cent. (1880), by weight, 640 grains. < rlycerin 3 fl. ounces. Elixir, sufficient to make • 1 pint. Mix them and. after standing, filter. A fl. drachm contains 5 grains Phosphoric Acid. The dose is a teaspoonful to .1 dessertspoonful. This is about one-third the strength of Phosphoric Acid diluted. 358 ELIXIRIA — ELIXIRS. 728. Elixir Phosphorus. Phosphorus, fresh (not oxidized), ... \y 2 grain. Absolute Alcohol, 1 fl. ounce. Add the Phosphorus to the Alcohol contained in a small bottle and stop tightly, dissolve the Phosphorus in the Alcohol by gentle heat of water bath, then mix Glycerine, 3 fl. ounces, Elixir, 12 fl. ounces, and warm the mixture to about 140 F., and while the solution of Phosphorus is still warm add the mixture to it and mix thoroughly. Set aside in a well-stopped bottle in a cool place. A fl. drachm contains -j-fa grain of Phosphorus. The dose is a teaspoonful to a dessertspoonful. 729. Elixir Phosphorus Compound. Elixir Phosphorus and Nux Vomica. Tincture of Nux Vomica, 384 minims. Elixir Phosphorus, sufficient to make . 1 pint. Mix them by adding the Elixir gradually to the Tincture. A fl. drachm contains 3 minims of Tincture of Nux Vomica and y^j- grain Phosphorus. The dose is a teaspoonful. 730. Elixir Phosphorus, Iron, Quinine and Strychnine. Elixir Phosphorus (728), 8 fl. ounces. Elixir Phosphate of Iron, # Quinine and Strychnine (726), 8 fl. ounces. Mix them. A fl. drachm contains 1 grain Iron, y 2 grain Quinine,-^ grain Strychnine, and ^Lq- grain of Phosphorus. The dose is a tea- spoonful to a dessertspoonful. ELIXIRIA — ELIXIRS. 359 731. Elixir Pink Root Compound. Pink Root, in coarse powder, .... 2 ounces av. Senna Leaves, in coarse powder, . . . 1 ounce av. Balmony, ]/ 2 ounce av. Elixir Percolating Menstruum, q. s., about 18 fl. ounces. Sugar, 5 ounces av. Soluble Elixir Flavoring, 1 fl. ounce. Make by percolation as directed (512). A fl. drachm represents about 7 grains Pink Root, 3^ grains Senna, and 2 grains Balmony. This is an excellent preparation for worms, and is given in doses of a teaspoonful or more. 732. Elixir Propylamine. Propylamine (liquid), 64 minims. Elixir, I pint. Mix them. The dose is a tablespoonful, containing 2 minims of Propylamine. Elixir Chloride of Propylamine is made by dissolving 384 grains of Chloride of Propylamine in a pint of Elixir. A fl. drachm contains 3 grains of the salt. The dose is a tea- spoonful. 733. Elixir " Protoxide " of Iron. Solution " Protoxide " of Iron, . . . 2 fl. ounces. Elixir, 14 fl. ounces. Mix them. A fl. drachm contains 2 grains Protocitrate of Iron. The dose is a teaspoonful to a dessertspoonful. 734. Elixir Protoxide of Iron and Iodide of Calcium. Iodide of Calcium, 128 grains. Elixir Protoxide of Iron (733), .... 1 pint. Dissolve the salt in the Elixir. A fl. drachm contains 2 grains Protocitrate of Iron, and I grain Iodide of Calcium. The dose is a teaspoonful. 360 ELIXIRIA — ELIXIRS. 735. Elixir Protoxide of Iron and Iodide of Potassium. Iodide of Potassium, 384 grains. Elixir Protoxide of Iron (733), .... 1 pint. Dissolve the salt in the Elixir. A fl. drachm contains 2 grains Protocitrate of Iron and 3 grains Iodide of Potassium. The dose is a teaspoonful. 736. Elixir Protoxide of Iron and Quinine. Sulphate of Quinine 128 grains. Elixir Protoxide of Iron (233), .... 1 pint. Dissolve the Quinine salt by rubbing with separate portions of the Elixir, and filter. A fl. drachm contains 2 grains of Protocitrate of Iron and I grain of Quinine. The dose is a teaspoonful. 737. Elixir Protoxide of Iron, Quinine and Strychnine. Sulphate of Strychnine, i*4 grain. Elixir Protoxide of Iron and Quinine, . 1 pint. Dissolve the Strychnine by rubbing with separate portions of the Elixir, or add ijA fl. drachm of Solution Strychnine to a pint of the Elixir. 738. Elixir Pyrophosphate of Iron. Fcrro-phosphatcd Cordial Elixir. Pyrophosphate of Iron, 256 grains. Water, . 1 fl. ounce. Elixir, 15 fl. ounces. Dissolve the Pyrophosphate of Iron in the Water by the aid of heat ami add the Elixir. After standing, filter. A fl. drachm contains 2 grains of the Iron salt. ELIXIRIA — ELIXIRS. 361 739. Elixir Pyrophosphate of Iron and Quinine. (Neutral.) Sulphate of Quinine, 64 grains. Citric Acid 10 grains. Pyrophosphate of Iron, 128 grains. Water of Ammonia, q. s., . . . . 20 to 30 drops. Water, 1 fl. ounce. Elixir, 15 fl. ounces. Dissolve the Citric Acid in a portion of the Elixir and rub the Quinine salt in a mortar with the solution, then add the remainder of the Elixir and warm the mixture gently by a water-bath until the salt is entirely dissolved; dissolve the Iron salt by the aid of heat in the water, and add to the solu- tion 20 drops of 10 per cent. Water of Ammonia, then add the Quinine solution to the Iron solution and mix them thor- oughly. When cool, filter. If the Elixir, when cool, remains cloudy, add a few drops more of Water of Ammonia to make clear. A fl. drachm contains 1 grain of the Iron salt and ]/>, grain Quinine. The dose is a'teaspoonful to a dessertspoonful. This Elixir was formerly prescribed and sold as Elixir Phos- phate of Iron and Quinine, but since the introduction of a sol- uble scale Phosphate of Iron the Elixir No. 725 is now fur- nished by that name. 740. Elixir Pyrophosphate of Iron, Quinine and Strychnine. (Neutral.) Sulphate of Strychnine 2 grains. Elixir Pyrophosphate of Iron and Quinine, 1 pint. olve the Strychnine salt by rubbing with separate por- tions of the Elixir, or add 2 ll. drachms of solution of Strych- nine to a pint of Elixir of Pyrophosphate of Iron and Quinine. [t may also be made the same as directed tor the preceding formula by adding to the solution of Citric Acid in Elixir 2 grains of Sulphate of Strychnine before adding the Quinine salt. 362 ELIXIRIA — ELIXIRS. A fl. drachm contains I grain of the Iron salt, y 2 grain Qui- nine, and ¥ * T grain Strychnine. The dose is a teaspoonful or more. This Elixir was formerly called Elixir Phosphate of Iron, Quinine and Strychnine, as explained in the foregoing formula. Elixirs of Pyrophosphate of Iron and Cinchonidine, with their various combinations, are made in the same manner as Elixirs Pyrophosphate of Iron and Quinine, only using Sul- phate of Cinchonidine instead of Sulphate of Quinine. A great variety of combinations are made with Elixir Pyro- phosphate of Iron, Quinine, and Strychnine. It is unnecessary to give detailed formulae for them as they are made simply by adding- various salts and solutions to the Elixir. 741. Elixir Pyrophosphate of Iron and Quinine. The foregoing Elixirs of Pyrophosphate of Iron and Qui- nine being neutral cannot be made to hold much more than y 2 grain of Quinine in a fl. drachm in solution. The following formula is made to contain 1 grain in a fl. drachm : Sulphate of Quinine, 128 grains. Phosphoric Acid, 50 per cent., 1880, . I fl. drachm. Alcohol, 1 fl. ounce. Pyrophosphate of Iron, 256 grains. Water, 1 fl. ounce. Water of Ammonia, q. s., about ... 20 minims. Elixir sufficient to make 1 pint. Dissolve the Quinine Salt in 8 ounces of the Elixir, the Alcohol, and the Phosphoric Acid. Dissolve the Pyrophos- phate of Iron in 1 ounce of Water by the aid of heat and add to the solution 6 ounces of Elixir and 20 minims Water of Ammonia. When the two solutions, the Quinine in one and the Iron in the other, are ready add the one containing the Quinine very gradually to the one containing the Iron, giving time for the precipitate formed to be dissolved after adding each portion before adding more. If not clear when all is ELIXIRIA — ELIXIRS. 363 added, add enough Water of Ammonia, mixed with a little Elixir to make clear, and filter. A fl. drachm contains 2 grains of the Iron salt and I grain Quinine. The dose is a teaspoonful. 742. Elixir Pyrophosphate of Iron, Quinine and Arsenic. Fowler's Solution of Arsenic, . . . 256 minims. Elixir Pyrophosphate of Iron and Quinine (741), 1 4H A. ounces. Mix them. A fl. drachm contains 2 grains Iron, 1 grain Quinine, and 2 minims Fowler's Solution. 743. Elixir Pyrophosphate of Iron, Quinine, and Strychnine. Sulphate of Strychnine, 2 grains. Elixir Pyrophosphate of Iron and Quinine, 1 pint. Dissolve the Strychnine salt by rubbing with separate por- tions of the Elixir, or add 2 fl. drachms solution of Strychnine to a pint of Elixir. A fl. drachm contains 2 grains of the Iron salt, 1 grain Qui- nine, and -fa grain Strychnine. 744. Elixir Quinine. Sulphate of Quinine 128 grains. Sulphuric Acid, q. s., about 10 minims. Elixir, I pint. Water of Ammonia, q. s., about ... 10 minims. Rub the Quinine salt to a powder and then with the Elixir to a smooth mixture, add Sulphuric Acid drop by drop until, after standing, the Quinine is entirely dissolved, then add a few drops of Water of Ammonia until the blue fluorescence of the solution has mostly disappeared. Filter. A fl. drachm contains 1 grain of the Quinine salt. The dose is a teaspoonful to a tablespoonful. 364 ELIXIRIA — ELIXIRS. 745. Elixir Quinine, Bismuth and Pepsin. Elixir Quinine (744), 8 fl. ounces. Elixir Pepsin and Bismuth (709), . . 8 fl. ounces. Mix them, and if any cloudiness occurs add Water of Am- monia drop by drop to clear. A fl. drachm contains ]/ 2 grain Quinine, }/ 2 grain Bismuth, and 1 grain Pepsin. The dose is a teaspoonful to a dessert- spoonful. 746. Elixir Quinine, Bismuth and Strychnine. Elixir Quinine {744), 8 fl. ounces. Elixir Bismuth and Strychnine (539), . 8 fl. ounces. Mix them, and, if necessary, add a few drops of Water of Ammonia to make clear. A fl. drachm contains y 2 grain Quinine, y 2 grain Bismuth, and y^-g- grain Strychnine. 747. Elixir Quinine Bisulphate. Bisulphate of Quinine, 128 grains. Elixir, 1 pint. Rub the Quinine salt with the Elixir until dissolved, and filter. A fl. drachm contains 1 grain Bisulphate of Quinine. The dose is a teaspoonful to a tablespoonful. 748. Elixir Quinine Phosphate. Sulphate of Quinine, 128 grains. Phosphoric Acid, 50 per cent. (1880), . 1 fl. drachm. Elixir, 1 pint. Rub the Quinine salt to a fine powder and then to a smooth mixture with the Elixir, add the Phosphoric Acid, dissolve and filter. A fl. drachm contains 1 grain of the Quinine salt. The dose is a teaspoonful or more. Other combinations of Quinine with Elixirs will be found under other headings. ELIXIRIA — ELIXIRS. 365 749. Elixir Rhubarb. Rhubarb, in coarse powder, .... \)A ounce av. Elixir Percolating Menstruum, q. s., about 1 pint. Sugar, 5 ounces av. Soluble Elixir Flavoring, 1 fl. ounce. Make by percolation as directed (512). This may also be made by mixing i.j4 ounce Fluid Extract of Rhubarb with enough Elixir to make a pint. A fl. drachm represents about 5 grains of Rhubarb. The dose is a teaspoonful to a tablespoonful. 750. Elixir Rhubarb and Columbo. Fluid Extract of Columbo, 256 minims. Fluid Extract of Rhubarb, 256 minims. Elixir, sufficient to make 1 pint. Mix, and after standing, filter. This may also be made by percolating Rhubarb and Col- umbo, each 256 grains, with Elixir Percolating Menstruum, 1 pint, adding 5 ounces sugar and 1 ounce Soluble Flavoring, and filtering. A fl. drachm represents 2 grains each, Rhubarb and Columbo. The dose is a teaspoonful to a dessertspoonful. 751. Elixir Rhubarb, Columbo, and Iron. Phosphate of Iron, in scales, .... [28 grains. Elixir Rhubarb and Columbo, .... 1 pint. Water I fl. ounce. Mix the Elixir with the white of one egg, and let stand for two days, with occasional agitation, then filter through cloth. Dissolve the Iron salt in water, by the aid of heat, and add to the detannated Elixir; after standing a few days, filter. A ll. drachm represents 2 grains each. Rhubarb and ( lolumbo, and 1 grain Phosphate of Iron. The dose is a teaspoonful to .1 dessertspoonful. 366 ELIXIRIA — ELIXIRS. 752. Elixir Rhubarb and Magnesia. Two Elixirs of Rhubarb and Magnesia are used, one con- taining sulphate of Magnesium (Epsom Salt) and the other Citrate of Magnesium in solution. The former is probably most used, but the latter is by far the more elegant preparation. MADE WITH SULPHATE OF MAGNESIUM. Sulphate of Magnesium (Epsom Salt), . 640 grains. Elixir Rhubarb (749), 15 fl. ounces. Rub the salts with the Elixir until dissolved. The dose is a dessertspoonful to a tablespoonful. MADE WITH CITRATE OF MAGNESIUM. Citric Acid, 3 drachms. Carbonate of Magnesium, 2 drachms. Water, 1 fl. ounce. Elixir Rhubarb (749), 15 fl. ounces. Rub the Carbonate of Magnesium with the Water and gradually add the Citric Acid. When effervescense has ceased add the Elixir Rhubarb, and mix thoroughly. The dose is a dessertspoonful or more. 753. Elixir Rhubarb and Potassium. Neutralizing Elixir. Rhubarb, in coarse powder, 160 grains. Bicarbonate of Potassium, 160 grains. Cinnamon, 80 grains. Golden Seal, 80 grains. Elixir Percolating Menstruum, ... 1 pint. Sugar, 5 ounces av. Spirit of Peppermint, 2 fl. drachms. Mix all together and macerate for several days, with occa- sional agitation, then filter, adding enough Elixir through the filter to make a pint. In making larger quantities of this Elixir it is best made by percolation as directed (512). This is the same strength as the " Neutralizing Cordial " of the American Dispensatory. The dose is a dessertspoonful to a tablespoonful. ELIXIRIA — ELIXIRS. 367 754. Elixir Rubrum. Red Elixir. As understood in American Pharmacy, Red Elixir is Simple Elixir colored red with carmine coloring, cochineal or cudbear. The Simple Elixir is often designated as Elixir Album or White Elixir. Red Elixir may be used as a base for Elixirs desired to be colored red, but in the formulas in this work the coloring is directed to be added to the Elixir when made. 755. Elixir Salicin. Salicin, 256 grains. Elixir, 1 pint. Rub the Salicin to a smooth mixture with the Elixir and heat by means of a water-bath until the salt is dissolved. A fl. drachm contains 2 grains of Salicin. The dose is a tea- spoonful to a dessertspoonful. 756. Elixir Salicylate of Propylamine. Salicylic Acid 1 ounce av. Propylamine (liquid), 2 fl. drachms. Alcohol, 3 fl. ounces. Elixir, sufficient to make 1 pint. Rub the Salicylic Acid with the Alcohol and Elixir and add the Propylamine, then, when dissolved, add the Elixir, and filter. A fl. drachm contains about 4 grains Salicylic Acid and I minim Propylamine, equivalent to 5 grains of the Salicylate of Propylamine. The dose is a teaspoonful for rheumatic troubles. 757. Elixir Salicylate of Sodium. Salicylate of Sodium, 640 grains. Elixir, sufficient to make I pint. Dissolve the salt in the Elixir, and filter. This Elixir may also be made by mixing 400 grains of Salicylic .Acid with 300 368 ELIXIRIA — ELIXIRS. grains of Bicarbonate of Sodium and dissolving the mixture in a pint of Elixir in a capacious vessel. When effervescense is over, filter. A fl. drachm contains 5 grains Salicylate of Sodium. The dose is a teaspoonful to a dessertspoonful or more for rheu- matic affections. 758. Elixir Salicylic Acid. Salicylic Acid 256 grains. Alcohol, 3 A. ounces. Elixir, sufficient to make 1 pint. Dissolve the Acid in the Alcohol, and gradually add the Elixir. A fl. drachm contains 2 grains Salicylic Acid. The dose is a teaspoonful to a dessertspoonful or more. 759. Elixir Santonin. Santonin, in very fine powder, ... 64 grains. Alcohol, 2 fl. ounces. Elixir, 14 A- ounces. Rub the Santonin with the Alcohol, and heat gently by water-bath until dissolved, then add the Elixir. A fl. drachm contains y 2 grain Santonin. The dose is a teaspoonful to a dessertspoonful. As Santonin is quite insol- uble, and it is not desirable to have it dissolved when taken as a vermifuge, it is best given in the form of an emulsion, or suspended in syrup or in powders. 760. Elixir Sarsaparilla Compound. Fluid Extract Sarsaparilla Compound, 4 fl. ounces. Elixir 12 fl. ounces. Mix them. This Elixir may also be made from the drugs directed for making 1 pint Fluid Extract Sarsaparilla Compound by percolating the ingredients as directed under Fluid Extract of Sarsaparilla Compound with Elixir Percolating Menstruum ELIXIRIA — ELIXIRS. 369 sufficient to make 52 fl. ounces, adding 20 ounces of Sugar and 4 fl. ounces soluble flavoring to make 4 pints of Elixir. This is of the same strength as Syrup Sarsaparilla Com- pound. The dose is a dessertspoonful or more. 761. Elixir Scilla Compound. Elixir Squill Compound. Squill, in coarse powder, 640 grains. Senega, in coarse powder, 640 grains. Tartrate of Antimony and Potassium, . 16 grains. Elixir Percolating Menstruum, q.s., about 18 fl. ounces. Sugar, 5 ounces av. Soluble Elixir Flavoring, ...... 1 fl. ounce. Make by percolation as directed (512.) This is the same strength as Syrup of Squill Compound. The dose is ^ to one teaspoonful or more. 762. Elixir Senna. Fluid Extract of Senna, 2^ fl. ounces. Elixir, sufficient to make I pint. Mix, and, after standing, filter. A fl. drachm represents 10 grains of Senna. Dose, a dessert- spoonful to a tablespoonful as a laxative. 763. Elixir Senna Compound. Senna Leaves, in coarse powder, . . 2 ounces av. Rhubarb, in coarse powder, .... 1 ounce av. Jalap, in coarse powder, y 2 ounce aw Mandrake, in coarse powder y 2 ounce av. Elixir Percolating Menstruum, q.s., about 18 fl. ounces. Sugar 5 ounces av. Soluble Elixir Flavoring, i 11. ounce. Make by percolation as directed (512). The dose is a tea- a/poonful to a dessertspoonful as a laxative, .1 tablespoonful as a cathartic. 370 ELIXIRIA — ELIXIRS. 764. Elixir Stillingia. Fluid Extract Stillingia, Alcohol 2 fl. ounces. Elixir, sufficient to make 1 pint. Mix them, and, after standing, filter. This may also be made by percolating 2^ ounces Stillingia with 2 ounces Alco- hol and 14 ounces Percolating Menstruum, adding 5 ounces of Sugar and 1 ounce Soluble Flavoring. A fl. drachm represents 10 grains Stillingia. The dose is a teaspoonful or more. 765. Elixir Stillingia Compound. Fluid Extract Stillingia Compound, . 4 fl. ounces. Elixir 12 fl. ounces. Mix them, and, after standing, filter. This may also be made by percolating the drugs as directed for making 1 pint Fluid Extract of Stillingia Compound with Elixir Percolating Men- struum until 52 fl. ounces have passed, then dissolving 20 ounces av. of Sugar in the percolate and adding 4 fl. ounces Soluble Flavoring to make 4 pints Elixir. This is the same strength as Syrup Stillingia Compound. The dose is a teaspoonful to a dessertspoonful. 766. Elixir Strychnine. Sulphate of Strychnine, 4 grains. Elixir I pint. Dissolve the Strychnine by rubbing with separate portions of the Elixir, adding a few drops of dilute Sulphuric Acid, or add 4 fl. drachms Solution Strychnine to a pint of Elixir and filter. A fl. drachm contains J* grain Strychnine. The dose is from y 2 to a teaspoonful. This Elixir is also made containing only 2 grains in a pint, or ,.' grain in a fl. drachm. ELIXIRIA — ELIXIRS. 371 767. Elixir Sumbul. Elixir of Musk Root. Sumbul, or Musk Root, 1280 grains. Elixir Percolating Menstruum, q. s., about 1 pint. Sugar, 5 ounces av. Soluble Elixir Flavoring, 1 fl. ounce. Make by percolation as directed (512), or mix 2^ fl. ounces of Fluid Extract of Sumbul with enough Elixir to make a pint and filter. A fl. drachm represents 10 grains of Sumbul. The dose is a teaspoonful to a dessertspoonful. 768. Elixir Sumbul Compound. Compound Elixir of Musk Root. Valerianate of Ammonium, .... 128 grains. Elixir Sumbul (767), 1 pint. Dissolve the salt in the Elixir and filter. A fl. drachm contains 10 grains Musk Root and 1 grain Valerianate of Ammonium. The dose is a teaspoonful to a dessertspoonful as a nervine. This Elixir is also called Elixir Sumbul and Valerianate of Ammonium. 769. Elixir Svapnia. Svapnia 128 grains. Elixir, 1 pint. Rub the Svapnia to a powder, and with the Elixir until dissolved and filter. A fl. drachm contains 1 grain Svapnia. The dose is a teaspoonful. 770. Elixir Taraxacum Compound. Tile formulas for this Elixir are given under the heading Elixir Dandelion Compound (626), which see. The formula was first given for this Elixir by Prof. P. C. Candidus of Mobile, 872 ELIXIRIA — ELIXIRS. and as this particular formula is still frequently called for, it is here repeated in substance : Dandelion Root, I ounce av. Wild Cherry Bark, l/^ ounce av. Gentian Root, l /% ounce av. Bitter Orange Peel ^ ounce av. Cinnamon, l /i ounce av. Liquorice Root, l / 2 ounce av. Star Anise, 30 grains. Caraway Seed, 30 grains. Coriander Seed, 30 grains. Elixir Percolating Menstruum, q.s., about 18 fl. ounces Sugar, 5 ounces av. Grind the drugs to a coarse powder, and make by percola- tion as directed (512). This Elixir is used as a vehicle for Quinine, and as an addition to other medicines. Also as a laxative and tonic in doses of a dessertspoonful or more. 771. Elixir Tartrate of Antimony and Potassium. Elixir Tartar Emetic. Tartrate of Antimony and Potassium, 16 grains. Elixir, 1 pint. Dissolve the salt by rubbing with separate portions of the Elixir, and filter. A fl. drachm contains }g grain Tartar Emetic. The dose is a teaspoonful to a dessertspoonful. This Elixir is a very convenient form in which to exhibit this salt, as the dose may be regulated as desired. 772. Elixir Valerian. Valerian Root, in coarse powder, . . . 1280 grains. Elixir Percolating Menstruum, q. s., about 1 pint. Sugar, 5 ounces av. Soluble Elixir Flavoring, I fl. ounce. ELIXIRIA — ELIXIRS. 373 Make by percolation as directed (512). This may also be made by mixing 2^ fl. ounces Fluid Extract Valerian with enough Elixir to make a pint, and, after standing, filtering. A fl. drachm represents 10 grains Valerian. The dose is a teaspoonful to a dessertspoonful or more. 773. Elixir Valerianate of Ammonium. Valerianate of Ammonium, .... 256 grains. Water of Ammonia, ioper ct.,q.s., about \]/ 2 fl. drachm. Elixir, 14 fl. ounces. Syrup, \]/ 2 fl. ounce. Dissolve the Valerianate in the Elixir, and add Water of Ammonia to neutralize the solution, then add the Syrup, and color with Carmine solution or other red coloring. A fl. drachm contains 2 grains of the salt. The dose is a teaspoonful to a dessertspoonful or more as an anodyne, ner- vine, and hypnotic. The object of adding the Water of Am- monia is to neutralize the free acid of the Valerianate of Ammonium, which isalways present. The quantity specified is generally about right, but it may be tested with test-paper for excess of acid and made just right. This formula makes the preparation usually used, but some houses furnish an Elixir containing Fluid Extract of Valerian 1 fl. ounce in each pint in addition to the above formula. Such an Elixir may be readily made if desired by adding 1 fl. ounce Fluid Extract Valerian, and filtering. It is thought to be more effective when thus made. 774. Elixir Valerianate of Ammonium with Chloral Hydrate. Hydrate of Chloral, crystallized, . . . 640 grains. Elixir Valerianate of Ammonium, suffi- cient to make i pint. 1 Hssolve iln- < Ihloral in the Elixir. A II. drachm contains 5 grain- Hydrate of Chloral combined with the Elixir. The dose is a teaspoonful to a dessertspoon- ful or more as a hypnotic and anodyne. 874 ELI X I RI A — ELIXIRS. 775. Elixir Valerianate of Ammonium and Iron. Pyrophosphate of Iron 128 grains. Water, 1 fl. ounce. Elixir Valerianate of Ammonium, . . 15 fl. ounces. Dissolve the Iron salt in the Water by the aid of heat, and add the Elixir. A fl. drachm contains 1 grain of Iron and 2 grains Valerian- ate of Ammonium. The dose is a teaspoonful to a dessert- spoonful. Other Salts of Iron may be added to the Elixir Valerianate of Ammonium in the same way. 776. Elixir Valerianate of Ammonium and Morphine. Morphine Sulphate, 16 grains. Elixir Valerianate of Ammonium, . . 1 pint. Dissolve the Morphine salt in the Elixir. A fl. drachm contains 2 grains Valerianate of Ammonium and ]/% grain Morphine. The dose is a teaspoonful. This is one of the most desirable combinations as a hypnotic and anodyne. 777. Elixir Valerianate of Ammonium and Quinine. Sulphate of Quinine, 64 grains. Valerianate of Ammonium, .... 256 grains. Water of Ammonia, about 20 minims. Elixir, sufficient to make 1 pint. Rub the Quinine salt to a smooth mixture with the Elixir, and add the Valerianate. When the Quinine is entirely dis- solved add the Water of Ammonia. This may be colored with a little Carmine coloring if desired. A fl. drachm contains 2 grains Valerianate of Ammonium and ]/ 2 grain of Quinine. The dose is a teaspoonful to a dessert- spoonful or more. A great variety of combinations may be made with this Elixir by adding other salts, as Strychnine, Iron, etc. ELIXIRIA — ELIXIRS. 375 778. Elixir Valerianate of Ammonium and Strychnine. Sulphate of Strychnine, 2 grains. Elixir Valerianate of Ammonium, . . 1 pint. Dissolve the Strychnine salt by rubbing with separate por- tions of the Elixir, and filter, or add 2 fl. drachms of Solution of Strychnine to a pint of the Elixir. A fl. drachm contains 2 grains Valerianate of Ammonium and t > T grain Strychnine. The dose is a teaspoonful. An Elixir is also made containing double the quantity of Strychnine, or 4 grains to a fl. drachm. 779. Elixir Valerianate of Iron. An Elixir of Valerianate of Iron may be made by dissolving 128 grains Valerianate of Iron, 60 grains of Citric Acid, and 60 grains Citrate of Potassium in a pint of Elixir ; but it is more expensive and less satisfactory than the Elixir Valerianate of Ammonium and Iron (775), which is therapeutically the same. 780. Elixir Valeriante of Morphine. Valerianate of Morphine, 16 grains. Elixir, I pint. Dissolve the salt by rubbing with separate portions of the Elixir. A ll. drachm contains ';> grain Valerianate of Morphine. The dose is a teaspoon ful. 781. Elixir Valerianate of Quinine. Valerianate of Quinine 64 grains. Citric Acid 10 grains. Elixir 1 pint. Dissolve the Valerianate by rubbing to a fine powder, add- ing tin ('it lit Arid and then rubbing with the Elixir. A fl. drachm contains '_< grain Valerianate of Quinine. The dose is a teaspoonful to a dessertspoonful. 376 ELIXIRIA — ELIXIRS. 782. Elixir Valerianate of Strychnine. Valerianate of Strychnine 2 grains. Elixir I pint. Rub the Strychnine salt with separate portions of the Elixir until dissolved.- A fl. drachm contains ^ grains Strychnine Valerianate. Dose, a teaspoonful. This Elixir is also made double the strength, or 4 grains Strychnine Valerianate in a pint. 783. Elixir Valerianate of Zinc. Valerianate of Zinc 64 grains. Elixir 1 pint. Dissolve the salt by rubbing with the Elixir. A fl. drachm contains }4 grain Valerianate of Zinc. The dose is a teaspoonful or more. 784. Elixir Veratrum Viride. American Hellebore, in fine powder, . . 256 grains. Elixir, 1 pint. Macerate for five days, and filter. This may also be made by adding 256 minims of Fl. Ext. Veratrum Viride to enough Elixir to make a pint. A fl. drachm represents 2 grains Veratrum Viride. The dose is y 2 to 1 teaspoonful. 785. Elixir Wild Cherry. Wild Cherry Bark, in coarse powder, . 2^ ounces av. Elixir Percolating Menstruum, q. s., about 1 pint. Sugar, 5 ounces av. Soluble Elixir Flavoring 1 fl. ounce. Make by percolation as directed (512). This may also be made by mixing 2^ fl. ounces of Fl. Ext. of Wild Cherry with enough Elixir to make a pint. A fl. drachm represents 10 grains of Wild Cherry. The dose is a teaspoonful or two. ELIXIRIA — ELIXIRS. 377 786. Elixir Wild Cherry, Detannated. Wild Cherry Bark, in coarse powder, . 2^ ounces av. Elixir Percolating Menstruum, q. s., about I pint. Sugar 5 ounces av. Soluble Elixir Flavoring, 1 fl. ounce. Make by percolation as directed (512), and detannate with Ferric Hydrate as directed (515). This Elixir is used with solutions of Iron salts, Bismuth, etc., that would form inky colors or precipitates with the former formula. Elixir Wild Cherry, from Cherry Pits. An Elixir may be made from Cherry Pits, which does not need to be detannated to combine with Iron, etc., by macerat- ing 2 ounces of Cherry Pits, crushed, with a pint of Elixir, for several days, and filtering. 787. Elixir Wild Cherry, Ferrated. Citrate of Iron and Ammonium, . . . 128 grains. Elixir Wild Cherry, Detannated (786), . 1 pint. Dissolve the Iron salt by rubbing with separate portions of the Elixir. A fl. drachm represents 10 grains of Wild Cherry and I grain of Citrate of Iron. The dose is a teaspoonful to a dessert- spoonful. 788. Elixir Wild Cherry, Ferriphosphated. Phosphate of Iron, in scales 1 1SS0) . . 128 grains. Water 1 il. ounce. Elixir Wild Cherry, Detannated (786), . 15 11. ounces. Dissolve the Iron salt in the water by the aid of heat and add the: Elixir to tin solution. A il. drachm represents 10 grains of Wild Cherry and 1 grain Phosphate of Iron, hose a teaspoonful to a dessertspoonful. 378 ELIXIRIA — ELIXIRS. 789. Elixir Wild Cherry Ferrophosphorated Pyrophosphate of Iron 128 grains. Water, 1 fl. ounce. Elixir Wild Cherry, detannated (786), . 15 fl. ounces. Dissolve the Iron salt in the Water, by the aid of heat, and add the Elixir to the solution. A fl. drachm represents 10 grains Wild Cherry and 1 grain Pyrophosphate of Iron. Dose, a teaspoon ful to a dessert- spoonful. The Elixirs of Wild Cherry and Iron may be combined with Bismuth, Strychnine, and other soluble salts which are com- patible with it. 790. Elixir Wild Cherry Compound. Wild Cherry Bark, I ounce av. Liquorice Root, Y / 2 ounce av. Marshmallow Root y 2 ounce av. Elixir Percolating Menstruum, q. s., about 1 pint. Sugar, 5 ounces av. . Soluble Elixir Flavoring, 1 fl. ounce. Make by percolation as directed (512). This Elixir is used chiefly as a vehicle for Quinine, for which it is excellent. It may be made by maceration instead of per- colation if desired. 791. Elixir Yerba Santa. Fluid Extract Yerba Santa, .... 2^ fl. ounces. Alcohol, 2 ' fl. ounces. Elixir, sufficient to make I pint. Mix, and, after standing, filter. A fl. drachm represents 10 grains Yerba Santa. The dose is a teaspoonful or more. ELIXIRIA — ELIXIRS. 379 792. Elixir Yerba Santa Compound. The following formula is adopted from the original, first published by Mr. J. S. McClary, of Los Angeles, Cal., who first brought to notice the advantages of Yerba Santa as a carrier for Quinine : Yerba Santa, 6 ounces av. Orange Peel, 2 ounces av. Cinnamon Bark, 1 Cloves, - of each, .... 3 drachms. Cardamom Seeds, ) Coriander Seed, | Caraway Seed, , . , L of each,. ... 2 drachms. Anise Seed, Cochineal, Glycerin, ' 1 pint. Alcohol, ]/z pint. Sugar, 4 pounds av. Water, sufficient to make 1 gallon. Powder the drugs coarsely, and, having mixed the Alcohol and Glycerin, moisten the powder and pack in the percolator, adding Water through the percolator, and continuing the per- colation until 6 pints of percolate are obtained. In this dis- solve the Sugar by gentle heat, and strain. This Elixir is used mainly to disguise the taste of Quinine and other bitter medicines. Other Elixirs. In the first part of this article, page 275, it was explained that Elixirs, as understood in American Pharmacy, were fla- vored, sweetened, weakly alcoholic preparations, in which medicinal substances are exhibited in pleasant, palatable form, etc. The foregoing formulae have corresponded to this descrip- tion, but there an- many preparations which have been known in the past as " Elixirs," whieh are not of this class, and which could not properly be included with it. The formulas for such 380 ELIXIRIA — ELIXIRS. of these as are most important, or likely to be called for, are therefore given here. Man)- of them have been official in foreign Pharmacopeias : 793. Acid Elixirs — DippeU's. — Sulphuric acid 1 part (by weight), alcohol 5 parts ; drop the acid gradually into the alcohol and macerate with 1 part cochineal and 1 part saffron. Hatter's. — Equal parts by weight of Sulphuric Acid and alcohol. See page 73- Voglers. — Equal parts by weight of Sulphuric Ether and nitrous ether. 794. Aloes Elixirs.— Compound Tincture of Aloes. — Acetate of potas- sium, inspissiated oxgall, Socotrine Aloes, myrrh each 120 grains, hay saffron 60 grains, brandy or proof spirit lyi flounces ; digest seven days and strain. Several other preparations are also known as Elixirs of Aloes. Tincture of Aloes and myrrh is sometimes known as Elixir Aloes Compound. 795. Elixir Amarum. — Biiter Elixir. — The present German Pharma- copoeia gives the following formula : Extract of wormwood 10 parts, oleo- saccharate of peppermint 5 parts, dissolve by triturating with water 25 parts, then add aromatic tincture 5 parts, bitter tincture 5 parts. 796. Anti-Asthmatic Elixirs. — Oil of anise, camphor, balsam of tolu each 1 ounce, cochineal 1 drachm, proof spirit 1 gallon; digest seven days and filter. Boerhaaves.— Anise seed, asarabacca, elecampane, liquorice root, orris root, and sweet Hag root of each 1 part, proof spirit 5 parts ; macerate and filter. 797. Elixir Antigoutteux de Villette. — Gout Elixir. — Cinchona bark 4 parts, poppy petals 2 parts, sassafras 1 part, guaiacum 2 parts, rum 160 parts, syrup sarsaparilla 100 parts; macerate and filter. 798. Boerhaave's Visceral Elixir. — Aloes, myrrh, and saffron, of each 1 ounce, tartrate of potassium 2 ounces, alcohol 14 fl. ounces, water 1 ounce; macerate three days and filter. 799. Claude's Elixir. — (Pideret.) — Salt of tartar, chloride of ammo- nium, aloes, and myrrh, each 1 ounce, elder flower water 25 fl. ounces; digest with agitation for 24 hours and filter. (Parish.) — Carbonate of potassium 1 ounce, aloes, guaiacum, myrrh, saf- fron, and rhubarb of each 2 drachms, water 18 fl. ounces; macerate a few days and decant. 800. Elixir Deslaurier's. — Toni-febrifuge, au Quinquina el Caffe. — Yellow cinchona bark 1Y2 ounces, brown cinchona bark 1 ounce, coffee slightly roasted 2 ounces, sugar i2>< ounces, sherry wine 2 pints, citric acid 1 50 grains ; powder the drugs, macerate seven days, filter, and dissolve the sugar in the filtrate. 801. Elixir Carminative, Dalby's. — Tincture of Opium 2% fl.ounces, tincture asafetida 1 % fl. ounce, essence of caraway yi ounce, essence of pep- ELIXIRIA — ELIXIRS. 381 permint i ounce, calcined magnesia %. ounce, tincture of castor t>/4 ounces, alcohol 4 n. ounces, syrup 30 fl.ounces ; mix. 802. Elixir de Garus. — Myrrh 90 grains, aloes 90 grains, cloves 1S0 grains, nutmeg 180 grains, saffron _;8o grains, cinnamon 360 grains, alcohol 12 pints; reduce the drugs to a coarse powder, macerate with the alcohol and distill 9 pints, which reserve ; then take maidenhair 4 tr. ounces, liquorice root y z tr.ounce, figs 3 tr. ounces ; infuse in 8 pints boiling water, strain, express, and dissolve in the liquid 12 pounds av. of sugar; mix equal parts by weight of the syrup thus prepared with the distilled spirit reserved. 803. Elixir of Gold. — Terchloride of Gold 20 grains, alcohol 6 fl. drachms. ether 3 fl. drachms. Dr. De la Motte's Golden Drops are also furnished under the name Elixir of Gold ; chloride of iron 1 part, alcohol 3 parts, ether 3 parts. 804. Elixir of Long Life. — Compound Tincture of Aloes (Codex). — Aloes 8 parts, gentian, rhubarb, zedoary, saffron, agaric, opium each 1 part, alcohol 400 parts ; macerate and filter. 805. Elixir Pectoral. — Balsam tolu 2 ounces, benzoin l% ounce, saffron y z ounce, alcohol 32 fl.ounces ; digest by gentle heat for four days and filter. The German Pharmacopoeia, 1883, gives the following under the name of Burst elixir or Pectoral Elixir (Elixir E Succo Liquiritiae) : Purified extract of liquorice 10 parts, dissolved in fennel water 30 parts, and added to anis- ated spirit of ammonia io parts; after standing the liquid is poured off from the sediment. 806. Elixir Salutis. — Elixir of Health, Duffy's Elixir.— This Elixir was formerly official under the title Tincture Senna Compound. Many for- mulas for it are extant. The following is from the Edinburgh Dispensatory : Senna 2 tr. ounces, jalap 1 tr.ounce, coriander y z tr.ounce. diluted alcohol 3^ pints; macerate and filter. To this 1 pound of sugar and other aromatics may be added if desired. 807. Elixir Stoughton's. — (Codex.) Aloes and cascarilla of each 1 drachm, rhubarb 3 drachms, gentian, germander, wormwood, and bitter orange peel of each 5 drachms, alcohol 60 proof 2 pints; macerate and filter. 808. Elixir Tonic- A number of old preparations are known by this name, as Elixir Roborans or Tincture Crown Hark, for which compound tincture of cinchona may be dispensed if called for. Elixir Tonique Autiglaireux de Guillie. A stomach tunic for diarrhoea, composed of a great number of drugs, etc. 809. Elixir Visceral, Hoffman's.— Elixir Orange Compound of the German Pharmacopoeia. Orange peel cut 50 parts, cinnamon bruised 10 parts, carbonate of potassium 2%. parts, sherry wine 250 parts; macerate for eight days and express ; add slurry wine to make 230 parts, and dissolve in the liquid extracts of gentian, wormwood, buckbean, and cascarilla each 5 pans; allow the mixture to settle, then filter. See, also. Iloerhaave's Visceral Elixir. 382 EMPLASTRA— PLASTERS. Besides the Elixirs of this kind which are here mentioned, are several which are official in the U. S. P., under other names, as Elixir Proprietatis (Tincture Aloes and Myrrh), Elixir Vitriol (Aromatic Sulphuric Acid), McMunn's Elixir of Opium (Deoderized Tincture of Opium), etc. There are also many which are not of sufficient general importance to require a formula for their prepa- ration. They may usually be prepared as wanted by intelligent druggists. EMPLASTRA — PLASTERS. The making and spreading of Plasters, which was formerly quite an important feature of the business of the apothecary, is now nearly a lost art as far as the retail druggist is concerned, the business having been relegated to manufacturers, who have experience and suitable machinery for the work, and furnish all the necessary combinations in the plaster line. In this country several large establishments are devoted entirely to the manufacture of plasters, and from long experience and experiment have perfected their products to a high degree. It is not therefore supposed that many druggists will attempt to make their spread plasters, but only such plaster masses as are occasionally used in making other preparations, or some- times called for in old formulas. For spreading Plasters in a small way the Plaster Iron is generally used. Plaster-spreading machines are advertised, but they are not generally practical. The following are the Plasters now official in the U. S., Br. and German Pharmacopoeias: 810. Emplastrum Ammoniaci. Ammoniac Plaster. Ammoniac, 5 ounces. Diluted Acetic Acid, 7 ounces. Digest the Ammoniac in the Diluted Acetic Acid until it is entirely emulsionized ; then strain and evaporate by means of a water-bath, stirring constantly until a small portion taken from the vessel hardens on cooling. EMPLASTRA — PLASTERS. 383 811. Emplastrum Ammoniaci cum Hydrargyro. Ammoniac Plaster with Mercury. Ammoniac, 4 ounces av. Mercury, 1 ounce av. Olive Oil. 19 grains. Sublimed Sulphur, 2^ grains. Diluted Acetic Acid, 5^3 fl. ounces. Lead Plaster, a sufficient quantity. Digest the Ammoniac in the Diluted Acetic Acid and pro- ceed as directed for making Ammoniac Plaster. Heat the Olive Oil and gradually add the Sulphur until they unite ; then add the Mercury and triturate until extinguished. Next, add gradually the Ammoniac Plaster while yet hot ; and, finally, having added enough Lead Plaster previously melted to make the mixture weigh 5^ ounces av., mix them thor- oughly together. The Br. formula corresponds with the U. S., 1870, Acetic Acid and Lead Plaster being omitted. 812. Emplastrum Arnicae. Arnica Plaster. Extract of Arnica Root, 1 ounce. Resin Plaster, 2 ounces. Add the Extract to the Plaster, previously melted by means of a water-bath, and mix them thoroughly. 813. Emplastrum Asafcetidae. Asafctida Plaster. Asafetida 3^ ounces av. Lead Plaster. 3*/ ounces av. Galbanum, \y 2 ounce av. Yellow Wax 1 ]/, ounce av. Alcohol 14 fl. ounces. Digesl the Gums with the Alcohol on a water-bath, and strain while hot; evaporate to the consistence of hone)-; then 384 K.MT I. ASTRA — PLASTERS. add the Lead Plaster and Wax, previously melted together, stir the mixture well, and evaporate to the proper consistence. 814. Emplastrum Belladonae. Belladonna Plaster. The U. S. 1880 formula directs to make a solid extract from Belladonna Root 100 parts, by exhausting with Alcohol and evaporating, and then to add to the Extract enough Resin Plaster, previously melted, to make 100 parts, and mix thoroughly. The Belladonna Extract is best made by water-bath perco- lation as directed. (See Extract Belladonna Root.) The Br. Pharmacopoeia directs: Alcoholic Extract of Belladonna, . . 1 part. Resin Plaster 2 parts. Soap Plaster, 2 parts. Melt the Plasters by the heat of a water-bath, then add the Extract, and mix the whole thoroughly together. 815. Emplastrum Capsici. Capsicum Plaster. The official Capsicum Plaster is made by first spreading Resin Plaster upon muslin and then brushing it over with a thin coating of Oleoresin of Capsicum, leaving a narrow blank margin along the edges. As furnished by manufacturers, the Oleoresin or Extract of Capsicum is first incorporated with the plaster mass before spreading. 816. Emplastrum Cantharidis. Cantliarides Plaster. In the U. S. P. this is classed among the Cerates, as Ceratum Cantharidis (376), which see. The Br. formula for Emplastrum EMPLASTRA — PLASTERS. 385 Cantharidis is given under the same heading. The German Pharmacopoeia gives two formulas, one being called Ernplas- trum CantJiaridam Ordinarium, or Spanischfliegenpflastcr , and the other Emplastrtim Cantharidum Perpetuum, or Zngpflaster. The former is similar to the U. S. Cerate Cantharidis ; the latter contains 23^ per cent. Euphorbium. 817. Emplastrum Cerussae. White Lead Plaster, Bleiweisspflaster. The G. P. gives the following formula: Lead Plaster, 60 parts. Common Olive Oil 10 parts. Carbonate of Lead, 35 parts. Melt the Lead Plaster and Olive Oil together and add the Carbonate of Lead ; boil the mixture, stirring frequently, and occasionally adding a little water until it is reduced to the consistence of plaster. 818. Emplastrum Ferri. Iron Plaster, Strengthening Plaster, U. S., Chalybeate Plaster, Br. The U. S., 1880, formula is: Hydrated Oxide of Iron, dried at a tem- perature not exceeding 8o° C. ( 1 76 F.) . i ounce. Canada Turpentine (Balsam Fir) 1 ounce. Burgundy Pitch, 1 ounce. Lead Plaster, 7 ounces. Melt the Lead Plaster, Balsam, and Pitch by means of a water-bath, then add the Oxide of Iron and stir continually until the mixture thickens on cooling. The Br. formula is Peroxide of Iron, in fine powder, 1 ounce. Burgundy Pitch 2 ounces, Lead Plaster 8 ounces. 386 EMPLASTRA — PLASTERS. 819. Emplastrum Fuscum Camphoratum. Universal Plaster, Mutterpfiastcr. The G. P. contains the formula for this Plaster, more famil- iarly known in this country as black plaster : Oxide of Lead, in fine powder, .... 30 parts. Common Olive Oil, 60 parts. Yellow Wax, 15 parts. Camphor 1 part. Boil the Oxide of Lead and Olive Oil together, constantly stirring until the mass has acquired a blackish-brown color, then add the Yellow Wax, and then, while cooling, the Cam- phor previously triturated with a little Olive Oil. 820. Emplastrum Galbani. Galbanum Plaster. The U. S. formula is : Galbanum, 8 ounces. Turpentine (Gum Thus.), 1 ounce. Burgundy Pitch 3 ounces. Lead Plaster, 38 ounces. To the Galbanum and Turpentine, previously melted together and strained, add, first the Burgundy Pitch and then the Lead Plaster, melted over a gentle fire, and mix the whole together. The Br. formula is Galbanum, Ammoniacum, Yellow Wax of each 1 ounce, Lead Plaster 8 ounces. 821. Emplastrum Hydrargyri. Mercurial Plaster. The U. S. formula is : Mercury, by weight, 3 ounces. Olive Oil, by weight, 1 ounce. Resin, by weight, 1 ounce. Lead Plaster, 5 ounces. Melt the Oil and Resin together, and, when they have become cool, rub the Mercury with it until extinguished; then EMPLASTRA — PLASTERS. 387 gradually add the Lead Plaster, previously melted, and mix the whole thoroughly together. The Br. formula is Mercury 3 ounces, Olive Oil 56 grains, Sublimed Sulphur 8 grains, Lead Plaster 6 ounces. It is made in a similar manner. The German formula resembles the U. S., but directs Tur- pentine (Gum Thus) instead of Resin. 822. Emplastrum Ichthyocollae. Isinglass Plaster, Court Plaster. This is made by dissolving 10 parts of Isinglass in enough hot water to make 120 parts ; one half of this solution is then spread in successive layers with a brush upon taffeta stretched on a level surface. The remainder of the solution is then mixed with 40 parts of Alcohol and 1 part of Glycerin, and the taffeta is again varnished with the solution as before. To make water-proof, varnish the back side of the taffeta with Tincture Benzoin. This method of preparing Court Plaster is similar to that used by manufacturers, except that the fresh fish-sounds are generally used for making the solution and that the taffeta is usually brushed over with the solution a great many times. Some manufacturers have machinery by which the solution can be more evenly spread. Court Plaster is made in various colors by coloring the solutions. It is also made on silk, thin muslin, and paper. For the retail trade it is put up in small packages containing different colored sheets, and sold as Court Plaster. For physicians' use it is furnished in yard rolls. 823. Emplastrum Opii. Opium Plaster. The U. S. formula is: Extract of Opium, 1 ounce. Burgundy Pitch 3 ounces. Lead Plaster \2 2 / l ounces. Water, 1^ ounces. Rub the Extract of ( )pium with the Water until uniformly soft, and add to it the Pitch and Lead Plaster, melted together 388 EMPLASTRA — PLASTERS. by means of a water-bath ; then continue the heat for a short time, stirring constantly, until the moisture is evaporated. The Br. formula is: Opium in finest powder i ounce or i part, Resin Plaster 9 ounces or 9 parts ; melt the Plaster by means of a water-bath, then add the Opium by degrees and mix thoroughly. 824. Emplastrum Picis. Pitch Plaster. The Br. P. gives the following formula. There is no corre- sponding U. S. formula : Burgundy Pitch, 26 ounces or parts. Common Frankincense, . . . 13 ounces or parts. Resin, 4^2 ounces or parts. Yellow Wax 4^ ounces or parts. Expressed Oil of Nutmeg. . 1 ounce or part. Olive Oil, 2 ounces or parts. Water, 2 ounces or parts. Add the Oils and Water to the Frankincense, Burgundy Pitch, Resin, and Wax, previously melted together ; then, con- stantly stirring, evaporate to a proper consistence. 825. Emplastrum Picis Burgundicae. Burgundy Pitch Plaster. Burgundy Pitch, 90 parts or 9 ounces. Yellow Wax, 10 parts or 1 ounce. Melt them together, strain the mixture and stir constantly until it thickens on cooling. 826. Emplastrum Picis Canadensis. Canada Pitch Plaster, Hemlock Pitch Plaster. Canada Pitch (Hemlock Gum), 90 parts or 9 ounces. Yellow Wax 10 parts or 1 ounce. Melt them together, strain the mixture and stir constantly until it thickens on cooling. EMPLASTRA — PLASTERS. 389 827. Emplastrum Picis cum Cantharide. Pitch Plaster, with Cantharides — Warming Plaster. {Emplastrum Calefaciens, Br.) The U. S. formula is: Burgundy Pitch, .... 92 parts or nj4 ounces. Cerate of Cantharides, . . 8 parts or 1 ounce. Heat the Cerate as nearly as possible to ioo° C. (21 2° F.) on a water-bath, and, having continued the heat for 15 min- utes, strain it through a close strainer which will retain the Cantharides. To the strained liquid add the Pitch, melt them together by means of a water-bath, and, having removed the heat, stir the mixture constantly until it thickens. The Br. formula directs an infusion of Cantharides 1 part in 5 parts of boiling water for six hours, then strain and press through a calico strainer and evaporate the liquid until it is reduced to % part. Expressed Oil of Nutmeg, Yellow Wax, and Resin each 1 part, Resin Plaster 13 parts, Soap Plaster 8 parts, are then melted together with the Extract of Cantha- rides, and well stirred until the whole is thoroughly mixed. 828. Emplastrum Plumbi. Lead Plaster, Diachylon Plaster, Litharge Plaster. The U. S. formula is : Oxide of Lead (Litharge), in very fine powder, 8 ounces. Olive Oil, by weight, 15 ounces. Water, a sufficient quantity. Rul) the Oxide of Lead with about one half the Olive Oil and add the mixture to the remainder of the Oil, contained in ;i suitable vessel of a capacity equal to three times the bulk of the' ingredients ; then add about 4 ounces of boiling Water and boil the whole together until a homogeneous plaster is formed, adding from time to time during the process a little Water as that first added is evaporated. 890 K.MPLASTRA — PLASTERS. The Br. formula directs 5 ounces of Oxide of Lead, 10 ounces of Olive Oil, and 5 ounces of Water, to be boiled together by the heat of a steam bath for four or five hours, stirring constantly until the product acquires a proper con- sistence for a plaster, adding more Water during the process if necessary. The German Pharmacopoeia directs equal parts of common Olive Oil, Lard and Oxide of Lead to be boiled together with Water in the same manner as above directed. It is called Emplastrum Lithargyri in the G. P. Lead Plaster is the basis of most of the official plasters. The British formula makes the best product. The Compound Lead Plaster {Emplastrum Lithargyri Com- position) of the German Pharmacopoeia is nearly identical with the Galbanum Plaster of the Br. P. 829. Emplastrum Plumbi Iodidi. Iodide of Lead Plaster. This is official in the Br. P., as follows : Iodide of Lead, 2 ounces or 1 part. Lead Plaster 16 ounces or 8 parts. Resin, 2 ounces or 1 part. Add the Iodide of Lead, in fine powder, to the Plaster and Resin, previously melted at as low a temperature as possible, and mix them intimately. 830. Emplastrum Resinae. Resin Piaster, Adhesive Plaster. The U. S. formula is: Resin, in fine powder, ... 14 parts or /£ ounce. Lead Plaster, 80 parts or 5 ounces. Yellow Wax 6 parts or ->8 ounce. To the Lead Plaster and Wax, melted together over a gen- tle fire, add the Resin and mix them. The Br. formula is Resin 4 ounces or 2 parts, Lead Plaster 2 pounds (av.) or 16 parts. Curd Soap 2 ounces or 1 part. To EMPLASTRA — PLASTERS. 391 the Lead Plaster, previously melted at a low temperature, add the Resin and Soap, first liquefied, and stir them until they are thoroughly mixed. This is the "Adhesive Plaster," which, when spread, is used so extensively in surgery. Druggists are familiar with the spread plaster but are little acquainted with the plaster mass. 831. Emplastrum Saponis. Soap Plaster. The U. S. formula is : Soap, dried and in fine powder, 10 parts or 1 ounce. Lead Plaster, 90 parts or 9 ounces. Water sufficient. Rub the Soap with Water until brought to a semi-liquid state, then mix it with the Lead Plaster, previously melted, and evaporate to the proper consistence. The Br. formula is Curd Soap 6 ounces, Lead Plaster 2^ pounds av., Resin 1 ounce. To the Lead Plaster, melted at a low temperature, add the Soap and the Resin, first liquefied ; then, constantly stirring, evaporate to a proper consistence. The German formula is Lead Plaster 70 parts, Yellow Wax 10 parts, melted together, and to the partially cooled mass add medicinal Soap, powdered, 5 parts, and Camphor, rubbed with a little Olive Oil, I part. 832. Emplastrum Saponis Fuscum. Brown Soap Plaster. I in Mr. formula directs : Curd Soap, in powder. ... 10 parts or ounces. Yellow Wax 12 parts or ounces. ( Hive ( )il 20 II. parts or ll. ounces. Oxide of Lead 15 parts or ounces. Vinegar 160 fl. parts or ounces. Boil the Vinegar and Oxide of Lead together by the heat of a steam bath, Constantly stirring them, until the Oxide has 392 EMPLASTRA — PLASTERS. combined with the Acid ; then add the Soap and boil again until most of the moisture is evaporated ; finally, add the Wax and Oil, melted together, and stir the whole continuously, maintaining the heat until, by evaporation of the remaining moisture, the product has acquired the proper consistence for a plaster. Other Plasters. The official Plasters for which formulae have been given embrace most that are used to any extent in pharmacy; but a few others deserve attention, and are therefore mentioned here : 833. Aconite Plaster. — This Plaster was formerly official in the U. S. P. It is made by exhausting 16 ounces of Aconite Root with Alcohol, evapor- ating to a soft extract and adding to it sufficient Resin Plaster, previously melted, to make 16 ounces. 834. Antimonial Plaster. — This is best prepared extemporaneously by sprinkling Tartar Emetic in very fine powder on the surface of common Adhesive Plaster or any kind of spread plasters. It is used as a counter- irritant. 835. Camphor Plaster.— For extemporaneous work Camphor in fine powder may be applied to the warmed surface of adhesive or other spread plaster. Several plasters containing Camphor are official. 836. Cancer Plaster.— Several Plasters are furnished for the purpose of removing Cancers. The one to which the greatest success is attributed is used by some of the most noted cancer doctors. Sheep-sorrel is gathered green and pounded to a pulp, the juice is expressed and dried on pewter plates to an extract ; this is then used as it is as a plaster, or combined with some sort of adhesive salve and applied. Another Cancer Plaster is made with Extract of Hemlock 1 drachm, Arsenious Acid in very fine powder 30 grains, Wax Plaster 1 ounce. Many other Cancer Plasters are used, most of them consisting of Arsenic combined with other substances. 837. Corn Plaster.— A great variety of Corn Plasters are found in the market, the most popular being made of Felt coated with Adhesive Plaster, and a hole punched in the centre to relieve the pressure from the corn. These are not in any way medicinal, but simply remove the pressure from the corn. To apply to corns in the form of a plaster, the following will be found effective : Salicylic Acid 60 grains, Beeswax 6 drachms, Venice Turpentine EMPLASTRA — PLASTERS. 393 2 drachms, Verdigris, in fine powder, 60 grains. Melt the Wax, add the Venice Turpentine, and mix in the other ingredients. 838. Croton-Oil Plaster. — The most common way of making a Croton- Oil Plaster is to rub a few drops of Croton-Oil over the surface of Adhesive or any spread plaster. It can also be made by melting Lead Plaster and adding 1 part of Croton-Oil to 6 parts of the plaster. 839. Elemi Plaster. — Wax Plaster 3 parts, Gum Elemi 1 part, melted together. This is also called Issue Plaster. 840. Euphorbium Plaster. — Burgundy Pitch Plaster 8 ounces, melted and mixed with Euphorbium in fine powder 1 drachm. Capuchin Plaster is sometimes furnished by the name of Euphorbium Plaster. It is made of Burgundy Pitch and Beeswax each 3 ounces, Venice Turpentine 1 ounce, melted together and then added to the mass Gum Ammoniacum, Olibanum, Mastich and Calamine, each 1 ounce. Euphorbium, Pyrethrum (pellitory) and Common Salt, all in fine powder, each 2 ounces. The whole is then well mixed together. 841. Extract Plasters.— A great variety of plasters may be made by mixing solid extracts of drugs with Burgundy Pitch Plaster, Resin Plaster, Lead Plaster, or other combined plasters. The plaster is first melted and the extract incorporated. The proportion is generally 1 part of extract to 9 parts of plaster. 842. Issue Plaster. — Beeswax 8 parts, Burgundy Pitch and Chian Tur- pentine, each 4 parts, Vermilion and Orris Root each 1 part. Many other stimulating plasters are used as Issue Plasters. 843. Mustard Plaster.— This is always made extemporaneously by mixing powdered Mustard to a stiff paste with warm water or vinegar. It is usually diluted with 3 or 4 parts of Corn-meal. Ginger Plaster may be made in the same way. Spread Mustard Plasters are prepared mustard spread upon paper. The formulae will be found under Charter Sinap/s (407). 844. Poor Man's Plaster.— This is another name for Pitch Plaster, which is conveniently made by melting together Beeswax 1 ounce, Resin 3 ounces. Tar 3 ounces, and spreading upon paper or cloth. 845. Quinine Plaster.— Quinine may be mixed with Adhesive, Wax or Lead Plaster, or any compound plasters, when melted, in the propor- tion of 1 part to 10, or any other proportion desired. Other alkaloids or their salts may also be combined in the same way. 846. Sticking Plaster or Sticking Salve.— A great variety of Sticking Salves or Plasters are found in the market, most of them being made of Bur- gundy Pitch combined with various ingredients and sold under various names. The following formula makes a first-class " Sticking Salve": Burgundy Pitch 6 parts, Resin 4 parts, Turpentine Gum 2 parts, Canada Balsam 1 part, Yellow Wax 2 parts, Venice Turpentine 1 part. Melt them 394 EMULSIONES — EMULSIONS. together. This may be colored green with Bayberry Wax 2 parts. It. is put up in small round sticks and sold by various names. 847. Verdigris Plaster. — Beeswax 4 parts, Burgundy Pitch 2 parts, melted together, and, while liquid, Venice Turpentine 1 part and powdered Verdigris 1 part added and stirred while cooling. 848. Wax Plaster or Simple Plaster.— Beeswax 3 parts, Yellow Resin 2 parts, Suet (fresh tallow) 2 parts, melted together and stirred while cooling. 849. Zinco-Lead Plaster.— Beeswax 8 ounces, Olive Oil 3 ounces, Black Lead 3 ounces, Carbonate of Lead 2 ounces, Calamine 1 ]/> ounce, Olibanum }i ounce. Melt and mix together to make a plaster. The foregoing are all the Plasters for which formuke are generally needed ; but many other combinations are made, and may occasionally be called for. The judgment of the druggist will generally enable him to prepare any com- bination that may be wanted. EMULSIONES — EMULSIONS. Emulsions are preparations in which an oil, liquid resin r balsam, or other fluid fatty matter is made to combine with water or aqueous solutions by means of some substance which combines with it to form a homogenous mixture in which the globules of oil or other substance are so broken up or divided as to be invisible except by a microscope. To fulfill the required conditions, an Emulsion must be of a uniform con- sistence, permanent without separation, miscible in all pro- portions with water, syrup or aqueous liquids, and sufficiently fluid to be poured readily from a bottle. To make such an Emulsion it is necessary to use the proper emulsifying ingre- dients in the proper proportions and to combine them in the proper manner, all of which requires an understanding of the method of making emulsions and care in preparing them. In medicine Emulsions are employed to render many nau- seating medicines palatable, and by minutely dividing the globules of oil, etc., fitting them for digestion and assimila- tion. They are mainly employed as nutritive food in debil- itated conditions. EMULSIONES — EMULSIONS. 395 Emulsificatioti is the process of making emulsions, which may be briefly described as follows : 850. General Directions for Preparing Emul- sions. To prepare Emulsions in a small way, choose a shallow- shaped mortar that will hold double the quantity of the Emul- sion desired to be made, and a pestle with a large flattened head. See that the mortar and pestle are perfectly dry, then put the powdered Gum Arabic in the mortar, and gradually add the water, rubbing it to a smooth paste: or if Acacia Mucilage Syrup is used, rub it with the pestle around the sides of the mortar. Then begin to add the Oil by pouring it very slowly from a bottle into the centre of the Gum Solution, constantly rubbing it with the pestie with a circular motion around the sides of the mortar. This will form a thick pasty mass, which should get thicker as more Oil is added. If the Oil does not combine as rapidly as added, stop pouring for a moment and work the mass with the pestle until it is homo- geneous. The Oil should be more slowly added as the process proceeds, and care must be used to maintain a coating of the pasty mass on the sides of the mortar and on the pestle, the Oil being broken up and emulsified between the two clinging surfaces thus presented. When all the Oil is added, the mass should be white and of a thick, pasty consistence, having no globules of Oil visible. The Flavoring Oils should then be added, the Glycerin or Syrup incorporated with the mass by rubbing them together, and then the water, to which is added any salts or solutions that are directed to be incorporated, should be gradually added and thoroughly rubbed with the pasty mass to complete the Emulsion. If any insoluble salts or other insoluble substances are to be added, they should be reduced to a very fine powder and nibbed with the Emulsion when completed. In making Emulsions it frequently happens that the Oil is added too fast to emulsify, or that the sides of the mortar be- come "greased" and will not "cling" to the Oil and break up its globules. It is then necessary to start the Emulsion over 396 EMULSIONES — EMULSIONS. again in a clean dry mortar, with a small quantity of fresh Mucilage Syrup, and work in the "cracked" Emulsion in the mortar in the same manner as at first. The clinging surfaces must be maintained or the Emulsion cannot be made. On a large scale Emulsions are best made in revolving churns or other apparatus by which the Oil and Mucilage may be thoroughly agitated. The Mucilage sufficient for the whole batch is first put in the churn and the inside thoroughly cov- ered, the Oil is then added in portions and the mixture well agitated after each portion is added. The Mucilage or Mucilage Syrup which is used for emulsi- fying must be sweet and fresh, and of a uniform consistence without lumps. 851. Acacia Mucilage Syrup. For making Emulsions it is most convenient to have a Mucil- age Syrup prepared and ready, for when made by rubbing powdered Gum Arabic with Water considerable delay is expe- rienced and the results are not always satisfactory. We have, therefore, found it desirable to have the following syrup pre- pared for this purpose : Best Gum Arabic, granulated, ... 6 ounces av. Albumen, (white of egg,) 8 fl. ounces. Glycerin, 4 fl. ounces. Boric Acid, 30 grains. Rub the Boric Acid to a very fine powder, and dissolve by rubbing with the Glycerin. Mix the solution with the Albu- men in a wide-mouth bottle or jar, add the Gum Arabic, and stir several times a day with a stick from the bottom, until the Gum is entirely dissolved, strain, if necessary, stop tight, and put away in a cool place. This requires two or three days to make, as heat cannot be used to effect the solution. It should be kept on hand, but it may be quickly made by using powdered Gum Arabic and rubbing with the Glycerin, etc., in a mortar. This is used as the emulsifying agent instead of Gum Arabic alone, as it is more effective. EMULSIONES — EMULSIONS. 397 852. Stronger Lime Water. Lime, in lump, selected, 1 ounce av. Water 14 fl. ounces. Sugar, 4 ounces av. Slack the Lime by pouring upon it half an ounce of hot water, and allowing to stand until it is reduced to a powder, add the Water and Sugar, allow to stand, and filter. This is sometimes used in making preparations of Cod Liver Oil that are sold as emulsions, although it does not make a true Emulsion, but rather saponifies the Oil, the Hydrate of Calcium uniting with the oleic acid of the Oil. 853. Emulsion Castor Oil. Taste/ess Cod Liver Oil. Castor Oil, 8 fl. ounces. Acacia Mucilage Syrup, 5 fl. ounces. Oil of Wintergreen, 20 minims. Water, 3 fl. ounces. Rub the Oils with the Syrup, and add the Water as directed (850). The efficacy of Castor Oil as thus prepared is very much increased, and it is not unpleasant to take. The dose is a dessertspoonful to a tablespoonful in milk or plain. It contains 50 per cent, of Oil. 854. Emulsion Cod Liver Oil. Tasteless Cod Liver Oil. Cod Liver Oil 8 fl. ounces. Acacia Mucilage Syrup 5 fl. ounces. Oil Hitter Almonds IO drops. ( )il Wintergreen 5 drops. Water 3 flounces. Rub the Oils with the Syrup and add the Water as directed (850'. This Emulsion'contains 50 percent, of ( )il, and is very 398 EMULSIONES — EMULSIONS. palatable if made from good Oil. The dose is a dessertspoon- ful to a tablespoonful. The New-York and Brooklyn Formulary gives the following: 855. Emulsio Olei Morrhuse Fortior. Stronger Emulsion of Cod Liver Oil. Acacia, in fine powder 2 ounces av. Sugar, in fine powder 4 ounces av. Cod Liver Oil 16 rl. ounces. Water, enough to make 28 fl.ounces. Mix the Acacia and Sugar with the Cod Liver Oil in a dry mortar, and add 8 fl.ounces of Water, then triturate thoroughly and continuously until the Oil is emulsified, and finally incorporate enough Water to make the product measure 28 fl.ounces. The Common Emulsion of Cod Liver Oil is made by mixing 14 fl.ounces of the Stronger Emulsion of Cod Liver Oil, 15 minims each Oil of Sassafras and Wintergreen, Water enough to make 16 fl.ounces. This makes a 50 per cent. Emulsion. Unless this Emulsion is very skillfully made it will soon separate, and it will soon ferment in warm weather. It is therefore good only for immediate use. 856. Cod Liver Oil with Lime. This is not a true Emulsion, but has every appearance of one, and is much sold both as plain Emulsion of Cod Liver Oil and as Emulsion of Cod Liver Oil and Lime. It is very conveniently made and gives good satisfaction, but thickens after a time, and is therefore not desirable to put upon the market. Cod Liver Oil, 8 fl.ounces. Stronger Lime Water, 4 fl.ounces. Syrup, 4 fl.ounces. Oil Bitter Almonds, 10 drops. Oil Wintergreen, 5 drops. This may be mixed simply by shaking together violently in a bottle. It is a valuable preparation whenever Lime is indi- cated in connection with Cod Liver Oil. The dose is a des- sertspoonful or more. EMULSIONES — EMULSIONS. 399 857. Emulsion of Cod Liver Oil with Hypo- phosphites of Lime and Soda. Cod Liver Oil, 8 fl. ounces. Acacia Mucilage Syrup, . . . ... . 5 fl. ounces. Hypophosphite of Calcium, . . . . 64 grains. Hypophosphite of Sodium, .... 64 grains. Oil Wintergreen, 10 drops. Oil Bitter Almonds, 5 drops. Water, 3 fl. ounces. Rub the Oils with the Mucilage Syrup, dissolve the salts, first reduced to a fine powder, in the Water, and add as directed (850). A dessertspoonful, which is the usual dose, contains 1 grain each of the Hypophosphites of Lime and Soda and 50 per cent, of Oil. This has been a very popular preparation, extensively sold as a proprietary remedy, and much prescribed in all parts of the country. Quite a number of combinations of this Emulsion with other preparations are found in the market, but they may be made generally as required by adding the desired ingredients. 858. Cod Liver Oil with Iodine. Cod Liver Oil, 8 fl. ounces. Acacia Mucilage Syrup, 5 fl. ounces. Compound Solution of Iodine, . . . 1 fl. ounce. Water, 2 fl. ounces. Oil Bitter Almonds, 10 drops. Rub the Oils with the Mucilage Syrup, add the Solution of Iodine and Water as directed (850). A dessertspoonful, which is the usual dose, contains % grain Iodine, 73 grain Iodide of Potassium, and 50 per cent. Cod Liver Oil. There is also a preparation called Iodized or lodinized Cod Liver Oil, which is a solution of Iodine in Cod Liver Oil, not an Emulsion. It is noticed under Proprietary Medicines. 40() EMULSIONES — EMULSN >NS. 859. Emulsion Cod Liver Oil, Iodo-Ferrated. Cod Liver Oil, 8 fl. ounces. Acacia Mucilage Syrup, 5 fl. ounces. Tasteless Iodide of Iron 128 grains. Water, 3 fl. ounces. Oil Bitter Almonds 10 minims. Oil Wintergreen, 5 minims. Rub the Oils with the Mucilage Syrup, dissolve the Iodide of Iron in the Water, and add the solution as directed (850). A teaspoonful, which is the usual dose, contains 2 grains Tasteless Iodide of Iron and 50 per cent, of Cod Liver Oil. There is also a preparation called Iodo-Ferrated Cod Liver Oil, which is not an Emulsion. See Proprietary Medicines. 860. Emulsion Cod Liver Oil with Iodide of Potassium. Iodide of Potassium, 256 grains. Water, 1 fl. ounce. Cod Liver Oil Emulsion (854), ... 15 fl. ounces. Dissolve the Iodide in the Water and mix with the Emul- sion. A dessertspoonful, the usual dose, contains 4 grains of Iodide of Potassium combined with Emulsion Cod Liver Oil. 861. Emulsion Cod Liver Oil with Iron. Emulsion Cod Liver Oil, Ferrated. Cod Liver Oil may be combined with an)' of the soluble salts of Iron, as the Phosphate, Pyrophosphate, Citrate, etc., and also with solutions of Iron, as Dialysed Iron, etc. The following formula may be used : Phosphate of Iron in scales, 1880 (or any other soluble salt of Iron), . . . .128 grains. Water, y 2 fl. ounce. Emulsion Cod Liver Oil (854), .... 1 pint. Dissolve the Iron salt in the Water by the aid of heat, and add the solution to the Emulsion, rubbing them well together. EMULSIONES — EMULSIONS. 401 A dessertspoonful contains 2 grains of the Iron salt and 50 per cent, of Cod Liver Oil. 862. Emulsion Cod Liver Oil with Lacto- phosphate of Iron. Solution Lacto-phosphate of Iron, . . ^ fl. ounce. Emulsion Cod Liver Oil (854), . . . 1 pint. Add the solution to the Emulsion and mix them thoroughly. A dessertspoonful contains 1 grain Lacto-phosphate of Iron combined with Emulsion Cod Liver Oil. 863. Emulsion Cod Liver Oil with Lacto-phos- phate of Lime. Solution Lacto-phosphate of Calcium, 1 fl. ounce. Emulsion Cod Liver Oil (854), ... 15 fl. ounces. Mix them thoroughly. A dessertspoonful contains 2 grains Lacto-phosphate of Lime with Emulsion Cod Liver Oil. This may also be made by rubbing 128 grains of Precipitated Lacto-phosphate of Lime with a pint of the Emulsion of Cod Liver Oil. 864. Emulsion Cod Liver Oil with Lacto- phospfiates Compound. Solution Lacto-phosphate of Iron, . . y 2 fl. ounce. Solution Lacto-phosphate of Calcium, 1 fl. ounce. Emulsion Cod Liver Oil (854), . . . 14^ fl. ounces. Mix the solutions with the Emulsion. A dessertspoonful contains 1 grain Lacto-phosphate of Iron and 2 grains Lacto-phosphate of Lime. This may also be made by rubbing 64 grains Lacto-phos- phate of Iron and 128 grains Lacto-phosphate of Calcium with a pint of Emulsion Cod Liver Oil. 40-2 EMULSIONES — EMULSIONS. 865. Emulsion Cod Liver Oil with Phosphate of Lime. Solution Phosphate of Calcium, ... 1 fi. ounce. Emulsion Cod Liver Oil (854), ... 15 fi. ounces. Add the solution to the Emulsion and mix them thoroughly. A dessertspoonful, the usual dose, contains 2 grains Phos- phate of Lime with Emulsion Cod Liver Oil. This may also be made by rubbing 256 grains Precipitated Phosphate of Lime with a pint of Emulsion Cod Liver Oil. 866. Emulsion Cod Liver Oil with Phosphates Compound. Cod Liver Oil with Cliemical Food. Concentrated Solution of Phosphates, y 2 fl. ounce. Emulsion Cod Liver Oil (854), . . . 1 pint. Add the solution to the Emulsion and mix them thoroughly. A dessertspoonful contains about 3^ grains of Mineral Phosphates with 50 per cent. Cod Liver Oil. 867. Emulsion Cod Liver Oil with Phosphate of Lime and Wild Cherry. Fluid Extract Wild Cherry, .... 2 fi. ounces. Emulsion Cod Liver Oil and Phosphate of Lime, 14 fl. ounces. Mix them thoroughly. Dose, a dessertspoonful. 868. Emulsion Cod Liver Oil with Pepsin. Saccharated Pepsin, 128 grains. Emulsion Cod Liver Oil (854), ... 1 pint. Rub the Pepsin first with a small portion of the Emulsion, and then with the remainder, and mix them thoroughly. A dessertspoonful contains 2 grains of Pepsin combined with Emulsion Cod Liver Oil. EMULSIONES — EMULSIONS. 403 869. Emulsion Cod Liver Oil with Pepsin and Quinine. Sulphate of Quinine 64 grains. Saccharated Pepsin, 128 grains. Emulsion Cod Liver Oil (854), ... 1 pint. Rub the Quinine and Pepsin together to a fine powder, then with a small portion of the Emulsion, and then with the remainder until thoroughly mixed. A dessertspoonful contains 1 grain Quinine, 2 grains Pepsin, and 50 per cent. Cod Liver Oil. 870. Emulsion Cod Liver Oil Peptonized. Peptonized Cod Liver Oil and Milk. Condensed Milk, 2 ounces. Saccharated Pepsin, 128 grains. Acacia Mucilage Syrup, 3 fl. ounces. Cod Liver Oil, 8 fl. ounces. Oil of Hitter Almonds, 10 minims. Oil of Wintergreen, 5 minims. Water, 3 fl. ounces. Rub the Condensed Milk with the Saccharated Pepsin and 1 fl. ounce of Water, and allow them to stand for 6 hours, then add the Mucilage Syrup, and rub the Oils with the mixture to make an Emulsion ; finally, add the Water as directed (850). The dose is a dessertspoonful to a tablespoonful. Many combinations may be made by mixing this with other preparations, solutions, salts, etc. 871. Emulsion Cod Liver Oil with Pancreatine. Pancreatine, in powder 128 grains. Cod Liver Oil, 8 fl. ounces. Glycerin, 3 fl. ounces. Water 3 (Pounces. Acacia Mucilage Syrup 2 fl. ounces. I )il Wintergreen, 10 minims. Oil Bitter Almonds, 5 minims. 404 EMULSIONES — EMULSIONS. Mix the Pancreatin with the Water and Glycerin, and let stand for 6 hours, then add the Acacia Mucilage Syrup, and rub the Oils with the mixture to make an Emulsion. A dessertspoonful contains 2 grains Pancreatine, with 50 per cent. Cod Liver Oil. 872. Emulsion Cod Liver Oil with Pancrea- tine and Pepsin. Pepsin, saccharated, 128 grains. Emulsion Cod Liver Oil and Pancreatine, 1 pint. Rub the Pepsin first with a portion of the Emulsion, then add the remainder. A dessertspoonful contains 2 grains each of Pepsin and Pancreatine with 50 per cent. Cod Liver Oil. 873. Emulsion Cod Liver Oil with Wild Cherry. Fluid Extract of Wild Cherry, ... 4 fl. ounces. Acacia Mucilage Syrup, 4 fl. ounces. Cod Liver Oil, 8 fl. ounces. Rub the Oil with the Mucilage Syrup, and add the Fluid Extract. A dessertspoonful contains y 2 drachm Fluid Extract Wild Cherry with 50 per cent. Cod Liver Oil. 874. Emulsion Cod Liver Oil with Yolk of Egg, Cod Liver Oil and Glyconin. A kind of Emulsion is made with the Yolks of Eggs by- shaking them with Cod Liver Oil and other ingredients : The Yolks of Eggs, 2^ fl. ounces. Glycerin, 3 fl. ounces. Diluted Phosphoric Acid, 2 fl. ounces. Sherry Wine, 4 fl. ounces. Cod Liver Oil, 10 fl. ounces. Old Bitter Almonds, 10 drops. Oil Wintergreen, 10 drops. EMULSIONES — EMULSIONS. 405 Beat the Yolks of Eggs and Glycerin together, then add the Oils gradually, shaking them well together after adding each portion. Lastly, add the Acid and Wine, and mix them well together. The dose is a dessert to a tablespoonful. A preparation made like this, but containing only half the quantity of Oil is known and prescribed as " Hospital Emulsion." 875. Cod Liver Oil Mixture with Hypophos- phites. The contents of two good-sized Eggs, white and yolk, about 3 fl. ounces. Cod Liver Oil, 8 fl. ounces. Oil Wintergreen, 10 drops. Oil Bitter Almonds, 5 drops. Hypophosphorous Acid, diluted (34), . 2 fl. ounces. Syrup Hypophosphites Compound, . 4 fl. ounces. Beat the Eggs with the Oils and add the Syrup and Acid. A dessertspoonful contains 2^ grains mixed Hypophos- phites and 50 per cent. Cod Liver Oil. Wine or Brandy may be added to this mixture if desired. 876. Cod Liver Oil Mixture with Phosphates. Cod Liver Oil with Chemical Food. The contents of two good-sized Eggs, white and yolk, about . . . . . 3 fl. ounces. Cod Liver Oil, 8 fl. ounces. Diluted Phosphoric Acid, I fl. ounce. Syrup Phosphates Compound, ... 4 fl. ounces. Oil Wintergreen, 10 drops. Oil Bitter Almonds, 5 drops. Beat the Eggs with the Oils and add the Syrup and Acid. A dessertspoonful contains nearly 2 grains mixed Phos- phates with 50 per cent. Cod Liver Oil. This may be mixed with Wine or Brandy if desired. 406 EMULSIONES — EMULSIONS. 877. Phosphorated Emulsion Cod Liver Oil. The contents of two good-sized Eggs, white and yolk, about 3 fl. ounces. Phosphoric Acid, diluted 2 fl. ounces. Syrup, 2 fl. ounces. Sherry Wine 4 fl. ounces. Cod Liver Oil 8 fl. ounces. Oil Bitter Almonds 10 drops. Oil Wintergreen, 5 drops. Beat the Eggs with the Oils, and add the Syrup, Wine and Acid. Dose, a dessertspoonful to a tablespoonful. 878. Cod Liver Oil with Extract of Malt. Cod Liver Oil, 8 fl. ounces. Extract of Malt, 8 fl. ounces. Oil Wintergreen, 20 minims. Oil Bitter Almonds, 5 minims. Rub the Oils with the Extract of Malt as directed for making Emulsions. The dose is a dessert to a tablespoonful, containing 50 per cent, each, Cod Liver Oil and Malt Extract. Extract of Malt makes a semi-solid palatable mixture with Cod Liver Oil, and is an excellent combination for debilitated conditions and wasting diseases. A great variety of combinations of Cod Liver Oil with Ex- tract of Malt may be advantageously made, but it is unneces- sary to give formulas for them, as they may be made by adding powders, Pepsin, Pancreatine, etc., or solutions, as Phosphate of Calcium, Phosphates Compound, etc., or other substances as may be desired. 879. Emulsion Copaiba. Acacia Mucilage Syrup, 6 fl. ounces. Balsam Copaiba, 4 fl. ounces. Syrup 3 fl. ounces. Water, 3 fl. ounces. Oil Wintergreen, 20 drops. EMULSIONES — EMULSIONS. 407 Rub the Oil and Balsam with the Mucilage Syrup, and add the Syrup and Water, as directed for making Emulsions. A fl. drachm contains 15 minims Balsam Copaiba. The dose is a teaspoonful to a dessertspoonful or more. 880. Emulsion Olive Oil. Acacia Mucilage Syrup, ..... 6 fl. ounces. Best Olive Oil, 8 fl. ounces. Oil Wintergreen, 20 minims. Water, 2 fl. ounces. Rub the Oils with the Mucilage Syrup and add the Water as directed (850). Dose, a dessertspoonful containing 50 per cent, of Oil. 881. Emulsion Turpentine. Acacia Mucilage Syrup, 6 fl. ounces. Syrup, 3 fl. ounces. Water, 3 fl. ounces. Oil of Turpentine, 4 fl. ounces. Oil of Wintergreen, 20 minims. Rub the Oils with the Mucilage Syrup, and add the Syrup and Water as directed (850J. A fl. drachm contains 15 minims Oil of Turpentine. The dose is half to a teaspoonful or more. 882. Emulsion Canada Turpentine. Emulsion Balsam Fir. Acacia Mucilage Syrup 6 fl. ounces. Water, 3 fl. ounces. Syrup 3 fl. ounces. Canada Balsam, 4 fl. ounces. Oil of Wintergreen, 20 minims. Rub the Oil and Balsam with the Mucilage Syrup, and add the Syrup and Water as directed (850). A fl. drachm contains 15 minims Canada Balsam. 408 EMULSIONES — EMULSIONS. Other Emulsions. A variety of other Emulsions may be made from fixed and volatile Oils, Balsams, Gums, Resins, Extracts, etc., in the same manner as the foregoing. A few sample formulas are given : 883. Emulsion of Almonds— Milk of Almonds. — Blanched Almonds, 1 ounce aw, beat to a pulp, with water gradually added sufficient to make 10 fl. ounces, and strained through gauze or cheese cloth. This may also be made with Oil of Almonds 3 fl. drachms, Acacia Mucilage Syrup 10 fl. drachms, Rose Water 1 fl. ounce, Distilled Water 3 fl. ounces. Rub the Oil with the Mucilage, then add the other ingredients. 884. Emulsion Asafetida. — Asafetida 1 ounce, Oil of Almonds 3 fl. ounces, Acacia Mucilage Syrup 4 fl. ounces, Water 3 fl. ounces. Warm the Asafetida with the Oil, and rub in a mortar until uniformly mixed, then rub with the Mucilage Syrup, and add the Water. This may be flavored with Peppermint if desired. Many other Gums or Gum Resins may be made into Emulsions in the same manner. 885. Emulsion Balsam Peru. — Balsam Peru 2 ounces, Acacia Mucilage Syrup 4 fl. ounces, Syrup 6 flounces, Water 4 fl. ounces. Rub the Balsam with the Mucilage Syrup, add the Syrup and Water. Emulsions of other liquid Balsams and Oleo-resins may be made in the same manner. 886. Emulsion of Wax. — White Wax 1 ounce, Acacia Mucilage Syrup 4 ounces, Water 1 2 ounces. Melt the Wax, and having warmed the Mucil- age Syrup to about i4o°F., rub the melted Wax with it in a mortar, and gradually add the Water, warmed to about ioo°F., rubbing them well together until cold. Emulsions of other waxes, Spermaceti, etc., may be made in the same manner. ESSENTIA — ESSENCES — FLAVORING EXTRACTS. The term Essoicc is applied in a general way to the import- ant or essential part or portion of plants or other substances, and in -pharmacy to a class of preparations made from or pos- sessing the essential principles of substances, such as Essential Oils or their solutions in alcohol, Ethers used as artificial flavors, Fluid Extracts or Tinctures of odorous substances used for flavoring or in perfumery, etc., etc. ESSENTIA — ESSENCES — FLAVORING EXTRACTS. 409 In the U. S. P. there is no mention of essences, but in the Br. P. Essence of Anise and Essence of Peppermint are assigned a place, being very much stronger solutions of the Essential Oils than the " Spirits" of the same. Many of the preparations which are commonly known as essences are found in the Spirits of the U. S. and other pharmacopoeias, and others are found among the Ethers, Fluid Extracts, Tinc- tures, etc. It is intended in this work to class under this heading only such preparations as are known as Essences and Flavoring Extracts — the esprits and essences used in perfumery being classed under perfumes. The preparations included under this classification are natu- rally divided into several departments, as solutions of Essential Oils or Essences proper, many of which are also known as Ex- tracts, Extracts of odorous substances used for flavoring, etc., Soluble Extracts or Essences used for flavoring beverages, Artificial Fruit, Essences or Flavors, and miscellaneous essences and extracts that cannot well be classified under any of these heading's. Concentrated Essences or Extracts. Solutions of Essential Oils. The Solutions of Essential Oils in Spirits have been famil- iarly known from time immemorial as " Essences," and the characteristic "Yankee Essence Peddler" is not even now entirely extinct in the rural districts. No uniform standard of strength has ever been adopted for Essences, but the general practice of Pharmacists in this coun- try is to use i ounce of the Oil in a pint of Alcohol for all the more common ones, but Peddlers' Essence is made much weaker as a rule. It is needless to remark that only the best quality of oils and good cologne spirit or alcohol should be used in making all these preparations. Many of them are used for flavoring soda water syrups, and are known as "Concentrated Extracts." Others are extensively used for flavoring confectioner)-, ice 410 ESSENTLE — ESSENCES — FLAVORING EXTRACTS. cream, and for culinary use, and some are well known domestic remedies. 890. Anise Essence. Oil of Anise, 1 fl.ounce. Cologne Spirit 15 flounces. Mix them. The Essence of Anise of the Br. P. contains 20 per cent, of the Oil. which is double the strength of the U. S. Spirit of Anise; both are stronger than is generally sold as Essence of Anise. 891. Bay Essence. Oil of Bay Leaves, 4 fi drachms. Cologne Spirit, 1 pint. Mix them. This is used for flavoring soups, etc., in place of the leaves. A soluble Essence of Bay for making Bay Rum may be made by dissolving 4 fl. drachms Oil of Bay in 6 ounces Cologne Spirit, rubbing 6 drachms of Car- bonate of Magnesium with 8 ounces of Water, adding the mixture to the solution, and filtering. 892. Bergamot Essence. Oil of Bergamot 1 fl.ounce. Cologne Spirit, 1 pint. Mix and filter. This Essence is considerably called for as a scent for hair preparations, etc. 893. Bitter Almond Essence. Oil of Bitter Almond 4 fl. drachms. Cologne Spirit 1 pint. Mix them. This is sold as the Concentrated Essence or Extract of Bitter Almond. A good ordinary Essence may be made by dissolving 1*4. fl. drachm of Oil Bitter Almond in 8 fl.ounces of Alcohol and adding 8 fl.ounces of Water. 894. Calamus or Sweet Flag Essence. Oil of Calamus, 1 fl.ounce. Cologne Spirit, 15 fl.ounces. Mix them. Used for flavoring confectionery, etc., and in making Bitters, etc. An extract may also be made by macerating 4 ounces av. of powdered Cala- mus in a pint of Alcohol. ESSENTIA — ESSENCES — FLAVORING EXTRACTS. 411 895. Caraway Essence. Oil of Caraway Seed . . 1 fl. ounce. Cologne Spirit, 15 fl.ounces. Mix them. Used for flavoring confectionery, pastry, etc. 896. Cardamom Essence. Oil of Cardamom Seed 4 fl .drachms. Cologne Spirit, 15 fl.ounces. Mix them. Used for flavoring, etc. The Oil of Cardamom is quite expen- sive, but of fine flavor. An extract may also be made by macerating 4 ounces of powdered Cardamom Seed in a pint of Alcohol. 897. Cassia or Cinnamon Essence. Oil of Cassia 1 fl. ounce. Cologne Spirit 15 fl.ounces. Mix them. The U. S. Spirit of Cinnamon contains 10 per cent, of the Oil ; the Br. contains but 2 per cent. 898. Cedar Essence. Oil of Cedar, 1 fl. ounce. Cologne Spirit ..15 fl.ounces. Mix them. 899. Celery Essence. Oil of Celery, 4 fl.drachms. Cologne Spirit 1 pint. Mix them. Used for flavoring. An extract is also made from Celery Seed. 900. Clove Essence. Oil of Cloves 1 fl. ounce. Cologne Spirit 1 pint. Mix them. Used for flavoring, etc. 901. Cherry Essence. Cherry Laurel Oil 4 fl.drachms. Cologne Spirit 1 pint. Mix them. Used for flavoring. 412 ESSENTIA — ESSENCES — FLAVORING EXTRACTS. 902. Cognac Essence. Oil of Cognac 2 fl. drachms. Cologne Spirit, 1 pint. Mix them. This is used for flavoring, also for making artificial Brandy. Good Oil of Cognac is very expensive. This Essence may be diluted, if desired, cheaper. 903. Coriander Essence. Oil of Coriander, 4 fl.drachms. Cologne Spirit 1 pint. Mix them. Used for flavoring. 904. Curacoa Essence. Oil of Curacoa, 1 fl. ounce. Cologne Spirit i5fl.ounces. Mix them. Used for flavoring, like Orange. 905. Dill Essence. Oil of Dill 1 fl.ounce. Cologne Spirit, 15 fl.ounces. Mix them. 906. Fennel Essence. Oil of Fennel Seed, 1 fl.ounce. Cologne Spirit 15 fl.ounces. Mix them. 907. Hemlock Essence. Oil of Hemlock 1 fl.ounce. Cologne Spirit 15 fl.ounces. Mix them. 908. Juniper Essence. Oil of Juniper Berries, 1 fl.ounce. Cologne Spirit 1 5 fl.ounces. Mix them. The U. S. Spirit of Juniper contains 3 per cent, of the Oil; the Br. P. directs 2 per cent. ESSENTIA — ESSENCES — FLAVORING EXTRACTS. 413 909. Lavender Essence. Oil of Lavender, 1 fl. ounce. Cologne Spirit, 15 fl. ounces. Mix them. The U. S. Spirit of Lavender contains 3 per cent, of the Oil ; the Br. P. directs 2 per cent. 910. Lemon Essence. Oil of Lemon, fresh, 1 fl.ounce. Fresh Lemon Peel, chopped fine or grated 1 ounce av. Cologne Spirit, 15 fl. ounces. Mix them and macerate for 7 days, then filter. The outer, yellow portion of the peel only should be used. If the fresh Lemon Peel cannot readily be obtained, color with a few chips of Fustic. This essence is the well-known Extract of Lemon, so much sold as a flavoring extract. It may be made stronger or weaker if desired by using more or less Lemon Oil ; but this formula makes an extract fully up to the standard. The U. S. P. directs 6 per cent, of Lemon Oil and 4 per cent, of Lemon Peel. 911. Lime Essence. Oil of Limes, 1 fl.ounce. Cologne Spirit, 15 flounces. Mix them. Used for flavoring, like Lemon. 912. Mace Essence. Oil of Mace, etherial 1 fl.ounce. Cologne Spirit, 15 flounces. Mix them. Used for flavoring, like Nutmeg. 913. Mustard Essence. Oil of Mustard, essential, 4 lldrachms. Cologne Spirit 1 pint. Mix them. Used for flavoring. The Oil of Mustard must be carefully handled. 914. Nutmeg Essence. Oil of Nutmeg I llounce. Cologne Spirit 15 fl.ounces. Mix them. Used for llavoring. The Br. P. directs 2 per cent, of the Oil for making Spirit of Nutmeg. 414 ESSENTIA — ESSENCES — FLAVORING EXTRACTS. 915. Orange Essence. Oil of Sweet Orange, fresh 1 fl .ounce. Fresh Orange Peel, outside, grated 1 ounce av. Cologne Spirit 15 rl. ounces. Mix them and macerate for 7 days, then filter. See remarks after Lemon Essence. 916. Parsley Essence. Oil of Parsley 4 fl. drachms. Cologne Spirit 1 pint. Mix them. Used for flavoring. 917. Pennyroyal Essence. Oil of Pennyroyal, 1 fl. ounce. Cologne Spirit 15 fl. ounces. Mix them, and filter. 918. Peppermint Essence. Oil of Peppermint 1 fl. ounce. Cologne Spirit 15ft. ounces. Mix them, and filter. It is customary with some druggists to color Essence of Peppermint green, which may be done by adding a little peppermint herb to the Essence, or a little grass-green coloring (443). The U. S. P. Spirit of Peppermint contains 10 per cent, of the Oil ; the Br. P. directs 2 per cent, of the Oil for making Spirit of Peppermint, but also gives an Essence of Pepper- mint containing 20 per cent, of the Oil. 919. Pimento or Allspice Essence. Oil of Pimento, 1 fl. ounce. Cologne Spirit, 15 fl. ounces. Mix them. Used for flavoring. 920. Rose Essence. Oil of Rose, ' . 1 fl. drachm. Cologne Spirit 1 pint. Mix them. This may be reduced if a cheaper Essence is desired. ESSENTIA — ESSENCES — FLAVORING EXTRACTS. 415 921. Rosemary Essence. Oil of Rosemary, 1 ii. ounce. Cologne Spirit, 15 fl. ounces. Mix them. 922. Sage Essence. Oil of Sage, 1 fl. ounce. Cologne Spirit, 15 flounces. Mix them. 923. Sarsaparilla Essence. Oil of Sassafras 3 fl. drachms. Oil of Wintergreen 4 fl.drachms. Oil of Anise, 30 minims. Cologne Spirit, 12 fl. ounces. Water 3 fl. ounces. Mix them. This is the popular " Sarsaparilla Flavoring" so much used for flavoring Soda Water, Syrup Sarsaparilla, etc. A stronger flavor can be made by using a larger quantity of the Oils and no Water. 924. Sassafras Essence. Oil of Sassafras, 1 fl. ounce. Cologne Spirit, 15 fl. ounces. Mix them. 925. Spearmint Essence. Oil of Spearmint 1 fl. ounce. Cologne Spirit 15 fl.ounces. Mix them. This may be colored with Spearmint herb or grass-green color- ing if desired. See remarks under Essence Peppermint. The U. S. P. Spirit of Spearmint contains 10 per cent, of the Oil. 926. Spruce Essence. oil of Spruce, 1 fl. ounce. Cologne Spirit, 15 fl.ounces. Mix them, and filter. 927. Wintergreen Essence. Oil of Wintergreen 1 fl. ounce. Cologne Spirit 15 ll. ounces. Mix them. The U. S. P. directs Spirits of Gaultheria to be made with 3 parts of < )il of Wintergreen and 97 parts of Alcohol. 416 ESSENTIA — ESSENCES — FLAVORING EXTRACTS. 928. Wormwood Essence. Oil of Wormwood 1 fl. ounce. Cologne Spirit 15 fl. ounces. Mix them. Essences of other Oils may be made in the same manner as the preceding, the judgment of the druggist directing how much of the Essential Oil should be used with a pint of Alcohol. Concentrated Extracts. In this department are included the liquid extracts of sub- stances, not Essential Oils, that are used as Flavoring Extracts, or for flavoring beverages, pastry, etc. Some of them are properly Fluid Extracts, others are Tinctures and others are mixtures both of Extracts and Essences. 929. Angelica Extract or Essence. Angelica Root, in coarse powder, 4 ounces av. Alcohol, 12 fl.ounces. Water, sufficient to make 1 pint. Mix 4 ounces of Water with the Alcohol, and macerate the drug in the mixture for 7 days, then pour off the liquid, transfer the drug to a percolator, and percolate first with the poured off liquid, then with Water, until a pint is obtained. This may also be made by mixing y 2 fl. ounce Oil of Angelica with a pint of Cologne Spirit. 930. Beef or Meat Extract, Essence or Juice. A variety of preparations are sold under this name. The Extracts of Meat or Beef are usually of the consistence of a soft, solid Extract, while some are gelatinous. The Essences of Beef found in the market are liquid. Of the Beef or Meat Extracts, Liebig's is the most popular. It is made on a large scale in South America by evaporating Meat Juices in vacuo in iron cylinders — the finished Extract representing 32 times its weight of fresh meat. It is much used in making Wine of Beef and Iron and other similar nutritive preparations, and for making soups and other articles of diet. Essence of Beef or Meat Juice is prepared from the expressed juice of fresh meat, condensed and preserved with glycerin. The most popular meat ESSENTIA — ESSENCES — FLAVORING EXTRACTS. 417 juice in this country is Valentine's. It is said to contain the nutritive value of two pounds of beef in a fl. ounce. In a small way Meat Juice may be made by chopping fresh beefsteak fine, enclosing it in a linen cloth, and pressing it in a lemon squeezer or a small press. It is much better and more nutritious than beef tea. 931. Chocolate Extract or Essence. Confectioners' Cocoa or Chocolate 1 6 ounces av. Alcohol, a sufficient quantity. Reduce the Cocoa or Chocolate to a coarse powder, and put in a wide- mouth quart bottle, pour upon it a pint of Alcohol, and shake them thoroughly together, let stand in a warm place for 12 hours, with occasional agitation, then heat in a water-bath for one hour or more to about i6o°F., leaving a little vent in the cork for the steam to escape. When cool, pour off the liquid and add half a pint more of Alcohol, heat as before, and add the product to the liquid before obtained to make about a pint of the Extract. The Choco- late may be still more thoroughly exhausted by adding more Alcohol, con- centrating the Tincture by distillation and adding the soft extract to the liquid formerly obtained. 932. Coffee Extract or Essence. Java Coffee, browned or roasted, 8 ounces av. Mocha Coffee, browned or roasted, 8 ounces av. Alcohol 8 flounces. Water, a sufficient quantity to make 1 pint. Grind the Coffee to a moderately fine powder, mix the Alcohol with 8 ounces of Water, and moisten the powder with 8 ounces of the mixture, pack firmly in the water-bath percolator, pour the remainder of the mixture upon it, and set in a warm place for one day, then heat moderately, and after one hour begin to percolate, adding Water through the percolator, and continuing the percolation until 14 ll. ounces are obtained, which reserve, continue the percolation with Water until the drug is exhausted, then evaporate to 2 fl. ounces, and add to the reserved liquid to make a pint. This is a Fluid Ex- tract of Coffee, It may be used for flavoring soda water syrups, etc., or medicinally. It requires about 4 fl.ounces to flavor a gallon of Coffee Syrup for soda water. 933. Jamaica Ginger Extract or Essence. Extracts or Essences of Jamaica Ginger arc well known as proprietary remedies, and are considerably used as flavors for pastry and other articles of diet. The following formula is for a Fluid Extract of Jamaica Ginger, 418 ESSENTLE — ESSENCES — FLAVORING EXTRACTS. which is used chiefly for flavoring, or may be diluted for the proprietary Essence of Jamaica Ginger : Jamaica Ginger, in moderately fine powder 16 ounces av. Alcohol, a sufficient quantity. Moisten the powder with Alcohol, pack firmly in a water-bath percolator, pour upon it sufficient Alcohol to cover it, and set in a warm place for 2 days, then heat moderately for one hour, and begin to percolate, adding Alcohol to the drug, and continuing the percolation until 14 flounces are obtained, which reserve ; continue the percolation with Alcohol until the drug is exhausted, then concentrate the later percolate by distillation to 2 fl. ounces, and add to the reserved portion to make a pint of Fluid Extract of Jamaica Ginger. This is used as a Flavoring for Soda Water Syrup and other beverages. To make the proprietary Essence of Jamaica Ginger, mix 3 parts of this Ex- tract with 5 parts of Cologne Spirit. 934. Orris Extract or Essence. Orris Root, in moderately fine powder 4 ounces av. Cologne Spirit, sufficient to make 1 pint. Moisten the powder with Cologne Spirit, pack firmly in water-bath perco- lator, cover with Cologne Spirit, let stand 2 days, then heat moderately 1 hour, and percolate with Cologne Spirit until a pint has passed. Used for flavoring and in compound perfumes. It has the odor of violets. 935. Sherbet Extract or Essence. Vanilla Extract (940) 6 fl. ounces. Oil of Orange, fresh 3 fl.drachms. Oil of Rose 3 minims. Acetate of Amyl 1 fl .drachm. Cologne Spirit, 8 fl. ounces. Mix them, and filter. 936. Tonka Extract or Essence. Tonka Beans, in fine powder 4 ounces av. Cologne Spirit, sufficient to make 1 pint. Moisten the powder with the Cologne Spirit, pack firmly in the water-bath percolator, cover with Cologne Spirit, and let stand for 2 days, then heat moderately and percolate with Cologne Spirit until a pint has passed. This was formerly much used to combine with Vanilla for making a cheap Vanilla Extract, but is now rapidly going out of use. It is considerably employed in perfumery. ESSENTLE — ESSENCES — FLAVORING EXTRACTS. 419 937. Vanilla Extract or Essence. A great variety of Extracts of Vanilla are found on the market, and as it is one of the most important Extracts, the selection of the beans for preparing it, and the manner of making, should be well understood. The Mexican Vanilla Beans have the finest flavor, and the longer the bean, as a rule, the better the Extract ; but owing to the increased value of the longer beans they are seldom used by the large manufacturers. The Bourbon Beans are considerably used, but they have a ranker flavor, more like Tonka, and a first-class Extract cannot be made from them alone. They are, however, used to mix with the Mexican Beans, and give a strength to the flavor, which is considered desirable by some manufacturers, but is not liked by the best judges of Good Vanilla Extract. Owing to the high price of Vanilla Beans, they are liable to manipulation in the hands of unscrupulous jobbers, and an Extract is frequently made by soaking the whole beans in spirits, then drying and selling them. They are then brittle and lighter colored, and are practically worthless. The best way- is to buy them of reliable houses only. Several strengths of Vanilla Extracts are made. One containing 4 ounces to a pint being usually called Fluid Extract of Vanilla ; one, containing 2 ounces to the pint, being called Concentrated Extract of Vanilla, chiefly used by confectioners and for flavoring soda water, etc. ; and one for the popular trade, usually made 1 ounce to the pint, and called by any name that the manufacturers chose to give it. Besides these, which rank as first-class, and vary only in strength, are the Extracts made of Vanilla and Tonka, or of poorer quality of beans, which are much sold by grocers and also by drug- gists. The following are the formulas : 938. Fluid Extract of Vanilla. Vanilla Beans, cut fine 4 ounces av. Cologne Spirit 12 flounces. Water, sufficient to make 1 pint. The Beans are best cut fine with a dried-beef sheer, or by chopping in a chopping-bowl ; they should then be pounded in an iron mortar until they are thoroughly crushed or dessicated, then pack them firmly in the water- bath percolator, and pour upon them 8 ounces of Cologne Spirit mixed with 4 ounces of Water, and set in a warm place for 2 days ; then heat moder- ately for 2 hours, and begin to percolate. When the liquid has ceased to drop add the remaining 4 ounces of Cologne Spirit, mixed with 4 ounces of Water, and continue the percolation, adding Water, if necessary, through the pen olator until a pint of the Extract is obtained, then filter. This Extract is not sold except as a Fluid Extract, or for special use to those who know its strength. 420 ESSENTIA — ESSENCES — FLAVI >RING EXTRACTS. 939. Concentrated Extract of Vanilla. Vanilla Beans, cut fine. 2 ounces av. Cologne Spirit, 12 fl.ounces. Water, sufficient to make 1 pint. .Make the same as the preceding. 940. Extract of Vanilla. This is the Flavoring Extract of Vanilla that is mostly made and sold by druggists and manufacturers when Extract of Vanilla is wanted : Vanilla Beans, cut fine 1 ounce av. Cologne Spirit 10 rl. ounces. Water, sufficient to make 1 pint. Reduce the Cut Beans to a coarse powder by beating in an iron mortar and put them in a pint wide-mouth bottle. Mix the Cologne Spirit with 6 ounces of Water, and pour one third of the mixture upon the Vanilla, and stop with a perforated cork, heat for one hour in a water-bath to about i6o°F., pour off the liquid and reserve ; pour on the drugs one third more of the menstruum, and heat as before, adding the liquid to the portion previously reserved. Pour on the remainder of the liquid, heat as before, and add the product to the reserved Extract, then add sufficient Water to the Vanilla in the bottle, heat again and pour off, adding the liquid to the reserved extract to make a pint of the Extract of Vanilla. In making larger quantities of this Extract, it is best made by water-bath percolation the same as the preceding. 941. Vanilla-Tonka Extract. Many druggists mix a portion of Tonka with Vanilla to make an Extract of Vanilla. Although it gives a stronger flavor, it is not the same as Vanilla. This is called by some manufacturers Fortified Extract of Vanilla, but those who are accustomed to the true Vanilla flavor think but little of it. It may be made by using : Vanilla Beans ?+' ounce. Tonka Beans X ounce. Alcohol, 10 fl.ounces. Water, sufficient to make 1 pint. Make in the same manner as Extract of Vanilla. Some manufacturers use a still larger proportion of Tonka. ESSENTIA — ESSENCES — FLAVORING EXTRACTS. 421 Soluble Flavoring Extracts. Most of the Essences and Extracts made from Essential Oils and substances containing Oleo-resins, are insoluble in aqueous solutions — making cloudy or milky mixtures. It is desirable for many purposes that some of them should make clear solutions when mixed with Water or Syrup. A general formula is therefore given by which any of the Essences made from Oils may be made soluble, and a few special formulae for others are given. These Soluble Extracts are mainly used for Soda Water Syrups and for making bottled beverages. 942. General Formula for Soluble Extracts. The Essential Oil or Oils ]/ 2 fl. ounce. Cologne Spirit, 9 fl. ounces. Carbonate of Magnesium '4 to 1 ounce av. Water, sufficient to make 1 pint. Mix the required Oil or Oils with the Cologne Spirit, rub half an ounce of Carbonate of Magnesium to a fine powder, and then with the Water, and add the mixture to the solution, shaking them well together, let stand a few days, shaking occasionally, then filter, adding enough Water through the filter to make a pint. As some Oils are much less soluble than others in aqueous solutions, the filtered product may not make a clear mixture with Water. This may be ascertained by dropping a few drops into a few ounces of Water. If the solution is cloudy it will be necessary to rub the filtrate with more Carbonate of Magnesium and again filter. 943. Soluble Extract of Ginger. Jamaica Ginger Root, in moderately fine powder, . . 4 pounds av. Al' oliol, a sufficient quantity. Water, a sufficient quantity. Carbonate of Magnesium 3 ounces av. Carbonate of Sodium (Sal Soda) 1 ounce av. ihe (linger in the water-hath percolator, and pour sufficient Alcohol upon ii to cover it, let stand 4v distilling off the Alcohol until only a pint of the Extract remains; add this to the per- colate reserved. Dissolve the Carbonate of Sodium in 4 pints of Water; rub 422 ESSENTIA — ESSENCES — FLAVORING EXTRACTS. the Carbonate of Magnesium to a smooth mixture with the solution, and add the mixture to the Extract. Let stand for several days, with occasional agita- tion, and finally filter. This is about half the strength of a Fluid Extract, and makes a clear solu- tion with Syrup or Water. It is used for flavoring Syrup for Soda Water, Ginger Beer, and other beverages. For making the U. S. official Syrup of dinger, mix i ll. ounce of this Extract with 15 H. ounces of Syrup. 944. Ginger Ale Extract. Jamaica Ginger, in moderately fine powder, .... 4. pounds av. Oil of Lemon 1 rl. ounce. Oil of Orange 3 fl.drachms. Oil of Pimento i)4 fl.drachms. Carbonate of Magnesium 4 ounces av. Carbonate of Sodium, 1 ounce av. Caramel Coloring, 2 fl. ounces. Alcohol, a sufficient quantity. Water, a sufficient quantity. Pack the Ginger in the water-bath percolator, and pour sufficient Alcohol upon it to cover it, let it stand 48 hours in a warm place, then add more Alcohol, heat moderately for 1 hour and begin to percolate, adding Alcohol to the percolator, and continuing the percolation until the drug is exhausted. Reserve the first 4 pints that pass, and concentrate the remainder by distilling off the Alcohol until only a pint of the Extract remains. Add this to the percolate reserved, then add the Oils to the same. Dissolve the Carbonate of Sodium in 4 pints of Water, rub the Carbonate of Magnesium with the solution, add the Caramel Coloring, and then add the mixture to the Extract. Let stand several days, with occasional agita- tion, and finally filter. This is the popular Ginger Ale Extract so much used as a flavoring for Soda Water Syrups and bottled beverages. For making Ginger Ale to bottle or charge in a fountain, mix 6 ounces of this Extract with i' 2 gallons of Syrup, 7 gallons of Water, 1 ounce solution Citric Acid and 2 ounces Caramel, and charge to 30 pounds. For making Syrup Ginger Ale to draw from the fountain, mix 3 ounces of the Extract with 1 gallon Syrup, and add l / z ounce solution Citric Acid. 945. Soluble Extract of Lemon. Oil of Lemon, fresh yb fl.ounce. Carbonate of Magnesium }4 ounce av. Cologne Spirit, 9 flounces. Water, q. s., or 8 fl. ounces. ESSENTIA — ESSENCES — FLAVORING EXTRACTS. 423 Dissolve the Oil of Lemon in the Cologne Spirit, rub the Carbonate of Magnesium with the Water, and add to the solution, let stand a few days, with occasional agitation, then filter, adding enough Water through the filter to make the measure one pint. . For making Lemon Pop, etc., mix 8 ounces of this Extract with 2 gallons of Syrup and 8 gallons of Water, add 1 ounce of Citric Acid, and charge to 30 pounds. For Soda Water Syrup, mix 3 ounces with 1 gallon of Syrup, and add 1 ounce Citric Acid Solution. 946. Soluble Extract of Mead. A great number of formulas have been published for making this popular beverage, some being in the form of Extracts, and others in the form of a Syrup. The following makes a soluble Extract of fine flavor and strength : Oil of Lemon 2 fl. ounces. Oil of Sassafras 4 fl.drachms. Oil of Cloves 3 fl.drachms. Oil of Wintergreen 1 fl.drachm. Oil of Pimento, 1 fl.drachm. Oil of Cinnamon, 40 minims. Caramel Coloring, 2 fl.ounces. Carbonate of Magnesium 4 ounces av. Cologne Spirit 4J^ pints. Water, q. s., or 4 pints. Dissolve the Oils in the Cologne Spirit, rub the Carbonate of Magnesium with the Water, and add the Caramel Coloring, then add the mixture to the solution, and let stand a few days, shaking occasionally, and filter. For charging in a fountain or bottling, mix 6 ounces of this Extract with i>2 gallons of Syrup, 7 gallons of Water, and 1 ounce Solution Citric Acid, and charge to 30 pounds. For making Syrup of Mead to diaw from the fountain, mix 3 ounces with 1 pint Strawberry or Raspberry Fruit Juice, and ]/z ounce Citric Acid Solu- tion, and add enough Syrup to make 1 gallon. 947. Excelsior Mead Extract. Fluid Extract Sarsaparilla Compound 4 fl.ounces. Strawberry Juice (or other Fruit Juice) 4^ pints. Soluble Mead Extract (946) 8 fl.ounces. Caramel Coloring 1 fl. ounce. Sugar 5 pounds av. Cologne Spirit 12 fl.ounces. Mix the liquids and dissolve the Sugar in the mixture. 424 ESSENTIA — ESSENCES — FLAVORING EXTRACTS. To charge in a fountain, or make Bottled Mead, mix i y z gallons of this Extract with i gallon of Syrup and 7^ gallons of Water, and charge to 30 pounds. For Excelsior Mead Syrup to draw from the fountain, mix 1 part with 3 parts of Syrup. 948. Soluble Extract of Orange. Oil of Orange y 2 fl. ounce. Carbonate of Magnesium % ounce av. Cologne Spirit 9 fl. ounces. Water, q. s., or 8 fl .ounces. Dissolve the Oil in the Cologne Spirit, rub the Carbonate of Magnesium with the Water, and add to the solution, let stand a few days, shaking occa- sionally, then filter, adding enough Water through the filter to make the measure a pint. For making Orange Syrup for Soda Water, mix 3 ounces with 1 gallon Syrup and x / z ounce Solution Citric Acid. 949. Soluble Extract of Sarsaparilla. Oil of Wintergreen, iy 2 rl.drachms. Oil of Sassafras 1% fl.drachm. Oil of Anise, 15 minims. Carbonate of Magnesium y 2 ounce av. Cologne Spirit 9 rl. ounces. Water, q. s., or 8 rl. ounces. Dissolve the Oils in the Cologne Spirit, rub the Carbonate of Magnesium with the Water, and add to the solution, let stand a few days, then filter, adding enough Water through the filter to make the measure a pint. For charging in a fountain, making Sarsaparilla Pop, etc., mix S ounces of this Extract with 2 gallons of Syrup, 8 gallons of Water, y 2 ounce Citric Acid, and 8 ounces Caramel Coloring, and charge to 30 pounds. For Soda Water Syrup, mix 3 ounces with 1 gallon Syrup, and color with Caramel. 950. Soluble Extract of Tolu. Balsam Tolu i}4. ounce av. Alcohol 3 flounces. Carbonate of Magnesium, 2 ounces av. Water, a sufficient quantity to make 1 pint. ESSENTIA — ESSENCES — FLAVORING EXTRACTS. 425 Dissolve the Balsam of Tolu in the Alcohol by the aid of a water-bath, and rub the solution thoroughly with the Carbonate of Magnesium, then gradually add to the mixture a pint of boiling Water, rubbing them well together, allow the mixture to stand until cold, then filter, adding through the filter sufficient Water to make the measure 16 fl. ounces. To make Syrup of Tolu, mix 2 fl.ounces of this with 14 flounces of Syrup. It is also used to flavor Soda Water Syrup in the same proportion. 951. Soluble Extract of Wintergreen. Oil of Wintergreen 3 fl.ounces. Carbonate of Magnesium )A. ounce av. Cologne Spirit 9 fl.ounces. Water, q. s., or 8 fl.ounces. Dissolve the Oil in the Cologne Spirit, rub the Carbonate of Magnesium with the Water, and add to the solution, let it stand for a few days, shaking occasionally, then filter, adding enough Water through the filter to make the measure a pint. For charging in a fountain, etc., use the same as Sarsaparilla. For Soda Water Syrup, mix 3 ounces with 1 gallon Syrup. 952. Birch Beer Extract. Oil Wintergreen 3 ll. ounces. ( )il Sassafras, y z tl. ounce. Oil Lemon l / 2 fl. ounce. Oil Cassia 10 minims. Catechu 60 grains. Carbonate of Magnesium 3 ounces av. Caramel Coloring 2 11. ounces. Cologne Spirit \V 2 pints. Water, q. s., or 4 pints. Dissolve the Oils in the Cologne Spirit, rub the Carbonate of Magnesium with the Water, add the Caramel and Catechu, and add the mixture to the solution, let stand several days, with occasional agitation, then filter. This Soluble Extract is much used by bottlers and for flavoring Soda Water Syrup. For Birch Beet charged in a fountain or bottled, mix 6 ounces with \ l / z gallon of Syrup, 2 ounces of Caramel, '. ounce Solution Citric Acid, 8 gallons of Water, and charge to 30 pounds. For Birch Beer Syrup to be drawn from the fountain, mix 3 ounces with 1 gallon of Syrup, and add '.. ounce Solution Citric Acid. Color with mel. 420 ESSENTLE — ESSENCES — FLAVORING EXTRACTS. 953. Ottawa Beer Extract. This was formerly a proprietary preparation, but now all the leading Soda Water manufacturers furnish it. A good Extract may be made as follows : Burdock Root, 1 pound av. Sarsaparilla 1 pound av. Sassafras, 8 ounces av. Sweet Flag (Calamus) 2 ounces. Dandelion Root 6 ounces av. Caramel Coloring 1 rl.ounce. Oil of Wintergreen 2 rl. drachms. Oil of Lemon, 2 fl. drachms. Carbonate of Magnesium, 1 ounce av. Alcohol 4 1 2 pints. Water, q. s. to make 1 gallon. Grind the drugs to a coarse powder, mix 4 pints of Alcohol with 4 pints of Water, make an Extract by water-bath percolation, reserving the first 7 pints that pass, continue the percolation with water, evaporate the remaining percolate to 1 pint, and add. Dissolve the Oils in 8 flounces of Alcohol, and add ; rub the Carbonate of Magnesium with a portion of the Extract, add to the remainder, and, after standing, filter. For Ottawa Beer charged in a fountain, mix 6 ounces with 1 yi gallon Syrup, 1 ounce Solution Citric Acid, 2 ounces Caramel, and 8 gallons of W 7 ater, and charge to 30 pounds. For Ottawa Beer Syrup, mix 3 ounces with l / z ounce Solution Citric Acid and 1 gallon of Syrup, and color with Caramel. 954. Peruvian Beer Extract. Fluid Extract of Sarsaparilla Compound, .... 4 rl. ounces. ( )il of Lemon 2 rl. drachms. Oil of Sassafras, 2 rl.drachms. Oil of Wintergreen 1% fl. drachm. Oil of Spruce, 1 rl.drachm. Oil of Nutmeg l /i rl.ounce. Carbonate of Magnesium 1 ounce av. Caramel Coloring ]/ 2 rl.ounce. Alcohol 16 rl.ounces. Water, .... 16 rl.ounces. Dissolve the Oils in the Alcohol, rub the Carbonate of Magnesium with the Water, add the Fluid Extract and Caramel, then add the mixture to the solution, and, after standing a few days, with occasional agitation, filter. Directions for charging, bottling and drawing as a Syrup the same as for Birch Beer. ESSENTIA — ESSENCES — FLAVORING EXTRACTS. 427 955. Root Beer Extract. American Sarsaparilla, 16 ounces aw Sassafras Bark 12 ounces av. Dandelion 12 ounces av. Sweet Flag (Calamus) 3 ounces av. Nutmeg 2 ounces av. Oil of Wintergreen 2 fl. drachms. Oil of Lemon, 2 fl. drachms. Oil of Spruce 1 fl. drachm. Caramel Coloring 1 fl. ounce. Carbonate of Magnesium 1 ounce av. Alcohol \Yz pints. Water, sufficient to make 1 gallon. Grind the drugs to a coarse powder; mix 4 pints of the Alcohol with 4 pints of Water ; make an Extract by water-bath percolation, reserving the first 7 pints which pass, and continue the percolation with Water until the drugs are exhausted ; evaporate this last percolate to 1 pint, and add to the reserved Extract. Dissolve the Oils in 8 ounces of Alcohol, and mix with the Extract. Rub the Carbonate of Magnesium with a portion of the Extract, and add to the remainder ; then add the Caramel, and, after standing a few days, with occasional agitation, filter. Directions for charging, bottling, and drawing as a Syrup the same as for Ottawa Beer. 956. Spruce Beer Extract. Oil Hemlock, pure 4 fl. drachms. Oil Lemon 1 11. drachm. Oil Wintergreen y 2 fl. drachm. Oil Sassafras > 2 fl.drachm. Carbonate of Magnesium 1 ounce av. Alcohol, 20 fl. ounces. Water 12 fl. ounces. Dissolve the Oils in the Alcohol, rub the Carbonate of Magnesium with the Water, and add to the solution ; let stand a few days, with occasional agita- tion, and filter. Directions for charging, bottling, and drawing as a Syrup the same as for Birch Beer, except that the color is omitted. Artificial Fruit Essences or Flavors. A variety of artificial Fruit Flavors or Essences arc made from various ethers, which, when Largely diluted, resemble the flavors of fruit t<> a greater or less degree. 4*28 ESSENTIA — ESSENCES — FLAVORING EXTRACTS. They are considerably used by bottlers and confectioners,. and were formerly much used for flavoring soda water syrups, but have now been superseded almost entirely by natural Fruit Juices, which are infinitely better for the purpose. The strongest preparations of this class are known in the market as Ethers or Fruit Oils, and generally consist of Amyl and Ethyl Oxides, either simple or combined ; but the prepa- rations that are generally furnished as Fruit Essences, Ex- tracts, or Flavors are diluted and mixed so as to more closely imitate the real flavor of fruit, some of them being very good imitations, while others are poor representatives of the natural fruit flavors. The following formula 1 represent all the flavors of this kind for which there is a demand, and make them about the same strength as are furnished by the leading manufacturers for this purpose. The)- may, however, be made stronger or weaker by using more or less Cologne Spirit or Alcohol in making them : 957. Apple Essence or Extract. Valerianate of Amyl . . . 1 %. fl. ounce. Acetic Ether, 1 ti drachm. Aldehyd, 1 tidrachm. CEnanthic Ether 30 minims. Glycerin, 2 flounces. Cologne Spirit or Alcohol 12 ti ounces. Mix them. This may also be made by mixing 3 fl. ounces of Valerianate of Amyl (which is also called Apple Oil) with 3 fl. ounces of Glycerin and io- flounces of Alcohol. 958. Apricot Essence or Extract. Butyrate of Amyl 1 fl. ounce. Valerianic Ether X/ 2 fl. ounce. CEnanthic Ether, 1 fl.drachm. Butyric Ether 2 fl.drachms. ( )il of Bitter Almond 20 minims. Glycerin 2 fl.ounces. Cologne Spirit 12 fl.ounces. Mix them. ESSEXTLE — -ESSENCES — FLAVORING EXTRACTS. 429 959. Banana Essence or Extract. Acetate of Amyl, 1 1 / 2 flounce. Butyrate of Amyl, . yi flounce. Chloroform 10 minims. Aldehyde 30 minims. Glycerin 2 11. ounces. Cologne Spirit 12 M. ounces. Mix them. A very good Essence of Banana may also be made by mixing 3 fl. ounces of Acetate of Amyl with 13 fl. ounces of Alcohol. 960. Blackberry Essence or Extract. Formic Ether 2 fl. drachms. Acetic Ether 6 fl. drachms. Butyrate of Amyl 1 fl. drachm. Acetate of Amyl 30 minims. Blackberry Juice 3 flounces. Glycerin, 2 flounces. Cologne Spirit 10 flounces. Mix them, and filter. 961. Black Cherry Essence or Extract. Benzoic Ether 4 fl.drachms. Acetate of Amyl 1 11. drachm. GEnanthic Ether 1 fl. drachm. Oil of Bitter Almond 30 minims. Black Cherry Juice 4 tl. ounces. Glycerin 2 II. ounces. Cologne Spirit 9 flounces. Mix them, and filter. 962. Black Currant Essence or Extract. Acetic Ether 1 flounce. I ither 1 ll. drachm. Extract of Orris (934) 2 fl.drachms. Black Currant Juice 5 flounces. Oil of Bitter Almond 20 minims. ( rlycerin 2 flounces. ■in- spirit 9 flounces. Mix them, and filter. 430 ESSENTIA — ESSENCES — FLAVORING EXTRACTS. 963. Blueberry Essence or Extract. Acetic Ether, 2 fl. drachms. Benzoic Ether 2 rl. drachms. CEnanthic Ether, 1 fl.drachm. Pelargonic Ether 30 minims. Blueberry Juice 5 flounces. Glycerin, 2 fl.ounces. Cologne Spirit, 9 fl.ounces. Mix them, and filter. This is also known as Huckleberry Extract. 964. Cranberry Ether or Extract. Acetic Ether, 2 fl. drachms. Formic Ether, 1 fl.drachm. Benzoic Ether, 1 fl.drachm. Wine Vinegar 2 fl.ounces. Cranberry Juice, .5 fl.ounces. Glycerin 2 fl.ounces. Cologne Spirit, 8 fl.ounces. Mix them, and filter. 965. Grape Essence or Extract. CEnanthic Ether 1 fl. ounce. Formic Ether 1 fl.drachm. Aldehyd, 1 fl.drachm. Grape Juice, any variety, 4 fl.ounces. Glycerin, 2 fl.ounces. Alcohol 9 fl.ounces. Mix them, and filter. The flavors of different varieties of Grapes may be imparted to this Essence by adding to it 2 fl. drachms of the Oil distilled from the required variety of grape, as Catawba, Sherry, Port, Claret, etc. These Oils are also produced artificially by combining various Ethers. 966. Gooseberry Essence or Extract. Acetic Ether 1% fl.ounce. Benzoic Ether 2 fl. drachms. CEnanthic Ether, 1 fl.drachm. Aldehyd '. . . 1 fl.drachm. Succinic Ether 1 fl.drachm. Glycerin 2 fl.ounces. Cologne Spirit 12 fl.ounces. Mix them. ESSENTLE — ESSENCES — FLAVORING EXTRACTS. 431 967. Melon Essence or Extract. Sebacic Ether, Valerianic Ether Butyric Ether, Aldehyd. . . Formic Ether. Glycerin, . . Cologne Spirit, Mix them. 1 fl.ounce. 3 fl.drachms. 2 fl.drachms. 1 fl. drachm. 30 minims. 2 fl. ounces. 12 fl. ounces. 968. Nectar Essence or Extract. Butyric Ether, . . . Oil of Wintergreen, Oil of Bitter Almonds, Extract of Vanilla (940J, Glycerin, Cologne Spirit, . . . Mix them, and filter. 1 fl. ounce. 60 minims. 15 minims. 3 fl. ounces. 2 fl. ounces. 10 fl. ounces. 969. Nectarine Essence or Extract. Butyric Ether ]A fl. ounce. Acetic Ether ]/ 2 fl. ounce. GEnanthic Ether >£ fl.ounce. Formic Ether ]/ 2 fl.ounce. Valerianic Ether )/% fl.ounce. Sebacic Ether 1 (1. drachm. Aldehyd 1 ll. drachm. ( '.lycerin 2 ll. ounces. Cologne Spirit 12 fl. ounces. Mix them. 970. Orgeat Essence or Extract. Oil of Bitter Almonds 2 fl.drachms. Acetic Ether 2 fl.drachms. Butyric Ether 4 11. drachms. Orris Extract (934) 1 5 ll. ounces. Mix them. 432 ESSENTIA — ESSENCES — FLAVORING EXTRACTS. 971. Peach Essence or Extract. CEnanthic Ether 4 H.drachms. Acetic Ether 4 fl.drachms. Butyrate of Amyl, 2 fl.drachms. Valerianic Ether 2 fl.drachms. Oil of Bitter Almonds 20 minims. Peach Juice, 4 flounces. Glycerin 2 flounces. Cologne Spirit 9 A -ounces. Mix them, and filter. 972. Pear Essence or Extract. Acetate of Amyl 1 flounce. Acetic Ether 4 fl.drachms. Glycerin 2 fl. ounces. Pear Juice 2 flounces. Cologne Spirit n fl.ounces. Mix them, and filter. The Essence of Jargonelle Pear is made the same as this, only using 30 drops of Acetic Ether. 973. Pineapple Essence or Extract. Butyrate of Amyl, 4 fl.drachms. Butyric Ether, 2 fl.ounces. Sebacic Ether, 4 fl.drachms. Acetic Ether 2 fl.drachms. Acetate of Amyl, 2 fl.drachms. Pineapple Juice, 2 fl.ounces. Glycerin 2 fl.ounces. Cologne Spirit 12 fl.ounces. Mix them, and filter. A very fair Essence of Pineapple is made by mixing 2 ounces of Butyric Ether with 12 ounces of Cologne Spirit and 2 ounces of Water. 974. Plum Essence or Extract. Acetic Ether, )/* fl.ounce. Aldehyd Yz fl.ounce. Butyric Ether 2 fl.drachms. Formic Ether, 1 fl.drachm. ESSENTLE — ESSENCES — FLAVORING EXTRACTS. 433 Oil of Bitter Almond, 30 minims. Plum Juice, 3 fl. ounces. Glycerin 2 fl. ounces. Cologne Spirit 9 fl. ounces. Mix them, and filter. 975. Prune Essence or Extract. Acetic Ether, y z fl.ounce. Aldehyd, l / 2 fl.ounce. CEnanthic Ether, 2 fl. drachms. Butyric Ether, ■. 1 fl. drachm. Formic Ether, 1 fl. drachm. Prune Juice, 3 fl. ounces. Glycerin 2 fl. ounces. Oil Bitter Almond 20 minims. Cologne Spirit 10 fl. ounces. Mix them, and filter. 976. Quince Essence or Extract. Pelargonic Ether, 1 fl.ounce. Aldehyd 1 fl. drachm. Chloroform 1 fl. drachm. Quince Juice 3 fl. ounces. Glycerin 2 fl. ounces. Cologne Spirit 10 fl. ounces. Mix them, and filter. 977. Raspberry Essence or Extract. Butyrate of Amyl, 2 fl.drachms. Acetic Ether 2 11. drachms. Benzoic Ether 1 fl. drachm. CEnanthic Ether 1 fl.drachm. Formic Ether 30 minims. Sebacic Ether 30 minims. Acetate )f Amyl 4 11. drachms. Extract of Orris 1 fl.ounce. Oil of Rose 2 minims. Raspberry Juice 3 fl.ounces. Glycerin 2 11. ounces. ne spirit 9 fl.ounces. Mix them, and filter. 434 ESSENTIA — ESSENCES — FLAVORING EXTRACTS. 978. Red Cherry Essence or Extract. Butyrate of Amyl, 2 fl.drachms. Benzoic Ether, 4 rl. drachms. Acetate of Amyl 1 rl. drachm. QEnanthic Ether, 1 rl. drachm. Oil of Bitter Almonds 30 minims. Red Cherry Juice 3 fl. ounces. Glycerin, 2 fl. ounces. Cologne Spirit, 10 fl. ounces. .Mix them, and filter. 979. Red Currant Essence or Extract. Acetic Ether, 1 fl. ounce. OZnanthic Ether 1 fl. drachm. Orris Extract, 2 fl. drachms. Red Currant Juice . 5 fl. ounces. Oil Bitter Almond 20 minims. Glycerin 2 fl. ounces. Cologne Spirit, 9 fl. ounces. Mix them, and filter. 980. Strawberry Essence or Extract. Acetic Ether, Butyric Ether, . Acetate of Amyl, Butyrate of Amyl, Formic Ether, . Extract of Orris, Strawberry Juice, Glycerin, . . . Cologne Spirit, . Mix them, and filter. 1 fl.ounce. 4 fl. drachms. 2 fl. drachms. 2 fl. drachms. 1 fl.drachm. 1 fl.ounce. 3 fl. ounces. 2 fl. ounces. 9 fl. ounces. 981. Wild Cherry Essence. Benzoic Ether 4 fl. drachms. CEnanthic Ether 1 fl.drachm. Acetate of Amyl, 1 fl.drachm. Oil of Cherry Laurel, 30 minims. Fluid Extract of Wild Cherry 3 fl. ounces. Glycerin, 2 fl .ounces. Cologne Spirit 10 fl. ounces. Mix them, and filter. ESSENTIA — ESSENCES — FLAVORING EXTRACTS. 435 982. Havana Cigar Flavoring. Tonka Beans, in fine powder 2 ounces av. Valerian, in fine powder 1 ounce av. Vanilla Beans, cut fine 1 ounce av. Beaver Castor, cut very fine 2 drachms. Benzoin, in fine powder 2 drachms. Balsam Peru 2 drachms. Oil of Cassia, 20 minims. Oil of Nutmeg 30 minims. Valerianic Ether 1 fl. ounce. Benzoic Ether, 1 fl.ounce. Acetate of Amyl, 2 fl. drachms. Cologne Spirit, 1 pint. Macerate the Tonka, Valerian, Vanilla, Castor and Benzoin in the Cologne Spirit in a warm place for seven days, then pour off the liquid, put the drugs in a percolator and percolate with the poured off liquid, adding through the percolator enough Cologne Spirit to make 14 fl. ounces, to this add the Oils, Ethers and Balsam, and mix thoroughly. 983. Cachou Flavor. Oil of Peppermint 2 rl. ounces. Oil of YVintergreen 1 fl.ounce. Oil of Cassia 2 fl. drachms. Oil of Cloves i fl. drachm. Mix them. By the addition of 2 drachms Oil of Calamus or the same quantity of Oil of Cardamom the flavor is much improved, but they add to the expense. Aromatic I achous for the breath are made by mixing powdered Extract of Liquorice 7 parts, powdered Purified Catechu 2 parts, powdered Cum Arabic 1 parr. Cachou Flavoring 1 part, with Water sufficient to make a mass, and making into pills which may be coated with silver leaf. Trix, a proprietary article, are made in the same manner, but rolled out in sheets and cut in small squares. The flavoring may be varied by adding other aro- matic substances, as desired. 984. Essence of Coltsfoot. Balsam Tolu 1 ounce av. pound Tincture of Benzoin 3 ounces. Alcohol 3 ounces. Mix the liquids, dissolve the Balsam in themixture by the aid of gentle heat, and filter. This is used for flavoring Coltsfoot Candy, and as a remedy for coughs. 436 ESSEXTI.E — BITTERS EXTRACTS. Bitters Extracts. These Extracts are used for flavoring Liquors and for making Bitters to bottle. They are dispensed at bars from squirt bottles, by which a few drops may be added to a glass of liquor, and are used as directed for flavoring put-up Bitters, for which druggists have considerable demand : 985. Angostura Bitters Extract. Angostura Bark, 16 ounces av. Bitter Orange Peel 8 ounces av. Canada Snake Root, 8 ounces av. Calisaya Bark 8 ounces av. Virginia Snake Root 8 ounces av. Gentian Root, 4 ounces av. Galangal Root 4 ounces av. Sweet Flag (Calamus) 4 ounces av. Cardamom Seed, 2 ounces av. Cinnamon, 1 ounce av. Cloves 1 ounce av. Coriander 1 ounce av. Mace, 1 ounce av. Alkenet Root 2 ounces av. Alcohol, 6 pints. Water, sufficient to make 1 gallon. Grind the drugs to a moderately tine powder, and moisten them with 2 pints of Alcohol, pack in the water-bath percolator, and, having mixed the remain- der of the Alcohol with 4 pints of Water, pour enough of the mixture upon the drugs to cover them, and set in a warm place, let stand 2 days, then pour the remainder of the diluted Alcohol upon them, heat very moderately, and after one hour begin to percolate, adding Water to the drugs, and continuing the percolation until the drugs are exhausted. Reserve the first 7 ' 2 pints that pass, evaporate the remainder of the percolate to a Y> pint, and add to the reserved portion to make 1 gallon. This is a very strong Extract. To make Angostura Bitters for bottling, take 2 ounces of this Extract, % gallon Pure Proof Spirit, % gallon Water, 1 ounce Glycerin. 986. Aromatic Bitters Extract. Bitter Orange Peel 2 pounds av. Sweet Flag Root (Calamus), 8 ounces av. Hops 8 ounces av. ESSENTIA — BITTERS EXTRACTS. 437 Cardamom Seed 2 ounces av. Cassia Bark 2 ounces av. Coriander Seed 1 ounce av. Cloves 1 ounce av. Mace 1 ounce av. Cochineal 1 ounce av. Alcohol 5 pints. Water, sufficient for 1 gallon. Grind the Orange and Hops to a coarse powder, and the other articles to a fine powder, mix them, moisten with 1 pint of Alcohol, pack, percolate, and proceed in the same manner as for making Angostura Bitters Extract. This is a pleasant Aromatic Extract. To make Aromatic Bitters to bottle, mix 4 fl. ounces of this Extract with 6 pints Pure Proof Spirit and 2 pints of Water, and add 1 ounce Glycerin. 987. Boker's Bitters Extract. Ouassia 8 ounces av. Sweet Flag Root, 8 ounces av. Bitter Orange Peel 12 ounces av. Catechu 4 ounces av. Cardamom 3 ounces av. Alcohol 5 pints. Water, sufficient to make \ gallon. Make by water-bath percolation same as the preceding. 988. Orange Bitters Extract. Fresh Orange Peel, chopped fine 2 pounds. I iitter Orange Peel, coarsely ground, 1 pound. Oil of Orange 1 fl.ounce. Cologne Spirit 6 pints. Water, sufficient to make 1 gallon. Mix the Orange Peels, fresh and dry, and cover them with Cologne Spirit, 4 pints ; let stand a f<-u days and pour off the liquid, pour on 2 pints fresh Cologne Spirit, macerate as before, and pour off, then pour 3 pints Water upon the drugs, macerate as before, pour off and express. Dissolve the Oil of < (range in the spiritous tincture, and add the last portion obtained by macer- ation and pressure to it. After standing a few days filter. To make Orange Bitten for bottling, add 8 il. ounces of this Extract to 6 pints I 'ure Proof Spirit, 2 pints of Water, and 1 ounce Glycerin. 438 ESSENTIA — BITTERS EXTRACTS. 989. Peruvian Bitters Extract. Peruvian or Calisaya Bark, in coarse powder, . . . \ l / 2 pound av. Bitter Orange Peel, in coarse powder i pound av. Galangal Root, in fine powder, [ ounce av. Cinnamon Bark 2 ounces av. Nutmeg, 1 ounce av. Cloves 1 ounce av. Alcohol 6 pints. Water, sufficient to make 1 gallon. Make by water-bath percolation the same as Angostura Bitters. To make Peruvian Bitters or Cinchona Bitters for bottling, mix 8 fl. ounces of this Extract with 6 pints of Pure Proof Spirit and 2 pints of Water, and add 1 ounce of Glycerin. 990. Stomach Bitters Extract. Wahoo Bark, 2 pounds av. Bitter Orange Peel 1 pound av. Hops 8 ounces av. Juniper Berries, 4 ounces av. Cardamom Seed 4 ounces av. Cinnamon, 3 ounces av. Cloves 1 ounce av. Nutmeg, 1 ounce av. ■ Alcohol 6 pints. Water 2 pints. Grind the Wahoo, Orange and Hops to a coarse powder and the other drugs to a fine powder, mix them and make by water-bath percolation as directed for making Angostura Bitters. To make Stomach Bitters for bottling, mix 4 ounces of this Extract with 6 pints of Pure Proof Spirit, and 2 pints of Water, and add 1 ounce of Gly- cerin. 991. Stoughton Bitters Extract. Gentian, in coarse powder 1 pound av. Virginia Snake Root, in coarse powder, ..... 8 ounces av. Bitter Orange Peel, in coarse powder, 1 pound av. Sweet Flag (Calamus), in coarse powder, .... 8 ounces av. Cardamom Seed, in fine powder, 4 ounces av. ESSENTIA — CORDIAL FLAVORS. 439 Cloves, in fine powder, i ounce av. Coriander Seed, in fine powder 2 ounces av. Red Saunders, in fine powder, 4 ounces av. Alcohol, 6 pints. Water, sufficient to make 1 gallon. Make by water-bath percolation as directed for Angostura Bitters. This is a strong extract and is to be diluted for use. 992. Wild Cherry Bitters Extract. Fluid Extract of Wild Cherry, 15 fl. ounces. Oil of Cherry Laurel, 60 minims. Cologne Spirit 1 fl. ounce. Dissolve the Oil in the Cologne Spirit, and mix with the Extract. A Wild Cherry Bitters may be made by mixing 6 ounces of this extract with 6 pints of Pure Proof Spirit, 2 pints of Water, and 1 ounce of Glycerin. Cordial Essences or Flavors. The following- are familiar Cordials which arc used for flav- oring Liquors, etc., similar to the foregoing Bitters. Other Cordials will be found under other headings. 993. Absinthe Essence. Absinthe is usually made by distillation from the drugs, but a good article may be made from this essence : Oil of Wormwood 4 flounces. 1 )il of Anise 2 ll. ounces. Oil of Fennel 2 fl. ounces. Oil of Coriander 1 fl.drachm. Cologne Spirit 8 flounces. Mix them. 994. Absinthe.- To make Absinthe mix 2 fl.ounces of Absinthe Essence with 5 gallons of ( Cologne Spirit, and add 5 gallons of water in which 5 pounds of white sugar has formerly been dissolved, then color by adding 2 (unices Quid Extracl of Wormwood and sufficient grass-green coloring to give the I tint, or by macerating 1 pound of fresh Wormwood tops in the liquid. Filter if necessary. 440 ESSENTIA — CORDIAL FLAVORS. 995. Anisette Essence. Many formulas, all differing somewhat in flavor, are employed for making Anisette. The following combination will be found as agreeable as any: Oil of Aniseed 8 fl.ounces. Oil of Coriander 1 fl.drachm. Oil of Cinnamon 1 fl.drachm. Oil of Nutmeg 30 minims. Oil of Neroli 30 minims. Cologne Spirit, 8 fl.ounces. Mix them. 996. Anisette or Anisette Cordial. — To make Anisette mix 2 fl.ounces of this essence with 4 gallons Cologne Spirit and add to the mixture 5 gallons of water and 1 5 pounds of white sugar. Let stand and filter through a little Carbonate of Magnesium, if necessary. 997. Kiimmel Essence. Oil of Caraway Seed 8 fl.ounces. Oil of Aniseed, 2 fl.drachms. Oil of Calamus 20 minims. Oil of Coriander 20 minims. Oil of Bitter Almond 20 minims. Cologne Spirit 8 fl.ounces. Mix them. 998. Kiimmel. — To make Kiimmel mix 2 fl.ounces of Kiimmel Essence with 4 gallons of Cologne Spirit and add 5 gallons of water in which 1 5 pounds of white sugar has previously been dissolved. Let stand and filter through a little Carbonate of Magnesium. A good Kiimmel may also be made by dissolving 1 fl.drachm Oil of Car- away Seed in 3 pints Cologne Spirit, adding 4 pints of water, \ x /z pounds of sugar, and filtering through Carb. Magnesium. Cura^oa Cordial is noticed on page 262. Some other cordials will be mentioned under other headings, but do not properly belong with the fore- going. ETHYL. The radical Ethyl is the most important of the series of hydrocarbons, known as the Alcohol radicals. Its combinations with various acids form a variety of Oxides, which are known as " Ethers," and its combination with the EXTRACTA — EXTRACTS. 441 elements of water forms the Hydrate of Ethyl, which is familiarly known as "Alcohol." See Ethers, page 78, and Alcohol, page 86. As most of the Ethyl Compounds have been noticed under these headings, further description here will be unnecessary. Ethylamine — NH 3 (C 2 H 5 ).— A base of the Ethyl series, obtained by substituting an atom of hydrogen in ammonia by the Ethyl radical. EXTRACTA — EXTRACTS. The class of Galenicals known as Extracts or Solid Extracts are preparations usually in the form of mass or powder, and intended to represent in a concentrated form the soluble por- tions of vegetable drugs. In pharmacy they are used for making pills, plasters, ointments, suppositories, and many other forms of medicine where a concentrated preparation is desirable. Various methods are employed for obtaining the soluble properties of the drugs, as may best be suited to their nature, and their solutions are then concentrated by evapora- tion in various ways to the required consistence. In large manufacturing establishments the evaporation is usually conducted in vacuo, at a low temperature, as the vola- tile properties are best preserved in this manner; but as this process is not expedient to the ordinary pharmacist, the for- mulas here given are designed for such conveniences as may readily be employed by them. I'Mi- making small quantities of Solid Extracts the fluid extract of the drug may be evaporated by a water-bath to a pilular consistence. For prescription work, Powdered Extracts are much used and are more convenient than extracts in mass. Many ex- tractS cannol well be reduced to a powder without admixture with other substances, but they are furnished by manufacturers who claim to give a true representative of the extract in the form of powder. 442 EXTRACTA — EXTRACTS. The following formulae are for Extracts Official in the U. S., Br. and German Pharmacopoeias. They represent, however, but a small part of the number of extracts that may be made, for it is evident that extracts may be prepared from all vegeta- ble drugs; but from the formulae given the intelligent druggist will have no trouble to prepare any extract that may be desired by using the same menstruum for exhausting the drug which is directed for making a Fluid Extract of the same and evap- oration in the manner directed for making other Extracts of the same nature. iooi. General Formula for Making Extracts. The general directions which apply to making all kinds of Extracts, may be briefly stated as follows : The Substance, any convenient quantity. The Menstruum, a sufficient quantity. Moisten the drug with the Menstruum, allow to macerate from 12 to 24 hours, pack in the water-bath percolator, pour Menstruum upon it and set in a warm place for one or two days, then heat moderately, adding the Menstruum or Water to the drug, and percolate until the drug is exhausted. Evaporate the percolate by distillation if it contains alcohol, or by gentle heat if aqueous, to a pilular consistence, adding 5 per cent, of Glycerin to such extracts as become hard and dry after standing, unless wanted in powdered form. 1002. Extracts from Expressed Juices. I nsp is sated Ju ices. The Extracts made by evaporating the expressed juices of fresh plants have always been considered superior to those made from the dried plants, and the popularity of the English Extracts made by reliable houses in this manner is well known. The following is the general process of the Br. P. for making extracts in this manner : The fresh leaves, tops or plants, any convenient quantity. EXTRACTA — EXTRACTS. 443 Bruise in a stone mortar and press out the juice, heat it gradually to 130 F. (54°4 C), and separate the green coloring matter by straining through a calico filter. Heat the strained liquid to 200 F. (93°3 C.) to coagulate the albumen, and again filter through calico. Evaporate the filtered liquid by a water- bath at a low temperature to the consistence of a thin syrup, then add to it the green coloring matter previously obtained, and pass through a hair sieve; then stir together and continue the evaporation at a temperature not exceeding 140 F. (6o° C.) until an extract of pilular consistence is obtained. 1003. Extractum Absinthium — Extract of Wormwood. — Exhaust Wormwood with Alcohol 2 parts mixed with water 3 parts, by means of the water-bath percolator. Distill off the Alcohol and evaporate the remainder to a thick extract. This is official in the G. P. The dose is %. to 2 grains. 1004. Extractum Aconiti — Extract of Aconite Root. — Exhaust Aconite Root with Alcohol by means of the water-bath percolator, distill off the Al- cohol until a thick extract remains, to which add 5 per cent of its weight of Glycerin and mix thoroughly. Official in the U. S. and G. P. Dose ^\ to X grain. 1005. Extract of Aconite Leaves.— This is official in the Br. P., and is made by bruising the fresh leaves and flowering tops of Aconite, expressing the juice, heating, evaporating, etc., as directed (1002). The dose is % to 1 grain. It was formerly official in the U. S. P. and was made by exhausting the dried Aconite Leaves with diluted Alcohol, distilling off the Alcohol and evap- orating the residue to a solid extract. 1006. Extractum Aloes — Extract of Aloes. — Dissolve Aloes 1 part in Water 10 parts, and strain. Set aside for 12 hours, then pour off the clear liquid from the residue and evaporate by a current of warm air or by the heat of a water-bath to dryness. The dose is from 2 to 6 grains. The V . S. P. calls this Aqueous Extract of Aloes ; the Br. directs an Ex- fcract both of Parbadoes and Socotrine Aloes. 1007. Extractum Arnicas Radicis — Extract of . Xrnica Root. — Exhaust Arnica Root with Diluted Alcohol, distill off the Alcohol and evaporate the remainder to a thick extract, add 5 per cent, of its weight of Glycerin, and mix thoroughly. An Extract of Arnica Flowers is made in the same manner. Extract of Arnica is used in making plasters. 1008. Extractum Belladonnae Alcoholicum — . //, 0/10/ic Extract of Belladonna. The r. S. P. directs this to be made from Belladonna I while the Br. P. directs the Root to be used ; the following formula will do for cither: Exhaust the Leaves or Root of Belladonna with Alcohol by means of 444 EXTRACTA — EXTRACTS. the water-bath percolator, distill off the Alcohol until only a soft extract remains, then evaporate to a pilular consistence, add 5 per cent, of its weight of Glycerin and mix thoroughly. Dose ^ to X grain. Under the name Extractum Belladonna the Br. P. and G. P. direct Ex- tract of Belladonna to be made from the fresh leaves, by bruising, expres- sing the juice, evaporating, etc., as directed (1002). The same process was official in the 1870 U. S. P. The dose is from X to l grain. 1009. Extractum Calumbae — Extract of Calumba. — Exhaust Calumba Root with diluted Alcohol, by maceration and pressure with separate por- tions of the menstruum, mix the liquors, distill off the Alcohol, and evaporate the residue to an extract of pilular consistence. The dose is 2 to 10 grains,. Br. P. 1010. Extractum Cannabis Indicae — Extract of Indian Cannabis. — Exhaust Indian Hemp with Alcohol by water-bath percolation, distill the Alcohol from the percolate until an extract of pilular consistence remains. The dose is X to J grain. 1011. Extractum Cascarae Sagradae — Extract of Cascar a Sagrada. — This is a new extract of the Br. P., and is made by exhausting the drug first with two parts of diluted Alcohol, then with Water by means of water-bath percolation. The Alcohol is then distilled from the first portion of the per- colate, and the residue, with the remaining percolate, is evaporated to an extract of pilular consistence. Dose from 2 to 8 grains. 1012. Extractum Cinchona? — Extract of Cinchona, Extract of Bar/:. — Exhaust Yellow Cinchona by means of the water-bath percolator, first with 2 parts of an alcoholic or partly alcoholic menstruum, then by continuing the percolation with water. Distill the Alcohol from the first portion of the per- colate and evaporate the residue together with the remainder of the percolate to an extract of pilular consistence, add 5 per cent, of its weight of Glycerin and mix thoroughly. The dose is 1 to 5 grains. The German Pharmacopoeia directs an Aqueous Extract of Cinchona to be made by exhausting the drug with separate portions of water, by macera- tion and expression, evaporation, etc.; also an Alcoholic Extract of Cinchona made with diluted Alcohol in the same manner. 1013. Extractum Cardui Benedicti — Extract of Blessed Thistle. — Blessed Thistle is exhausted with boiling water, and the liquid strained and evaporated to pilular consistence. The dose is from 3 to 30 grains. G. P. 1014. Extractum Cascarillae - Extract of Cascarilla. — Exhaust Casca- rilla in No. 40 powder with boiling water, strain the liquid and evaporate to pilular consistence. The dose is 2 to 20 grains. G. P. 1015. Extractum Calami — Extract of Calamus. — Exhaust Calamus Root in No. 30 powder by percolating in the water-bath percolator, first with diluted Alcohol, then with Water. Distill the Alcohol from the first portion of the percolate and evaporate the residue with the remainder of the perco- late to pilular consistence. This is official in the G. P. EXTRACTA — EXTRACTS. 445 1016. Extractum Colchici Radicis — Extract of Colchicwn. — The U. S. P. directs dried Colchicum Root to be used. The Extract may be made by exhausting the root with 35 per cent, of its weight of Acetic Acid and sufficient Water, with repeated maceration and pressure. The mixed liquids are then strained and evaporated at a low temperature to an extract of pilular consistence. The Br. P. makes an Acetic Extract of Colchicum from the fresh Corms deprived of their coats and crushed, using about 20 per cent, of their weight of Acetic Acid, macerating, pressing and evaporating to pilular consistence. The dose is y 2 to 2 grains. The Br. P. also directs an Extract of Colchicum to be made from the juice of the fresh Colchicum Corms by straining and evaporating at a low temperature. 1017. Extractum Colocynthidis — Extract of Colocynth. — Exhaust the pulp of Colocynth, deprived of seeds, with diluted Alcohol by maceration with separate portions of the Menstruum and expression. Distill off the Alcohol and evaporate the remainder by means of a water-bath to dryness. The dose is )i to % grain. 1018. Extractum Colocynthidis Compositum — Compound Extract of Colocyntii — Extract of Colocynth 8 ounces. Aloes 25 ounces. Cardamom in No. 60 powder, 3 ounces. Resin of Scammony, in fine powder 7 ounces. Soap, dried and in coarse powder 7 ounces. Alcohol 5 ounces. Melt the Aloes on a water-bath, then add the Alcohol, and having stirred the mixture thoroughly, strain it through a fine sieve, which has just been dipped into boiling water. To the strained mixture add the Soap, Extract and Resin, and heat the mixture not to exceed 248°F., until it is perfectly homogeneous, and a thread taken from the mass becomes brittle when cool. Then remove from the heat, add the Cardamom, mix thoroughly, and cover. This is much used in making Cathartic Pills. The dose is from 3 to 10 grains. 1019. Extractum Conii Alcoholicum — . Ucoholic Extract of Conium, — The U. S. formula is : Conium (fruit) in No. 40 powder 16 ounces av. Diluted Hydrochloric Acid yi ounce av. rin ami Diluted Alcohol each a sufficient quantity. Exhaust the drug with Diluted Alcohol, distill off the Alcohol, add the Diluted Hydrochloric Acid to the remainder, and evaporate by heat of water- bath not exceeding [22 I'. to a pilular consistence, to this add 5 per cent, of its weight of Glycerin, and mix thoroughly. The Br. P. directs it to be made from the Juice expressed from the bruised young branches and fresh leaves of I lemlock, as direi ted 1 1002). The dose is from 2 to 6 grains. 446 EXTRACTA — EXTRACTS. 1020. Extractum Digitalis — Extract of Digitalis. — Exhaust the Digi- talis by means of a water-bath percolator, first with 4 parts of a menstruum, consisting of % Alcohol, ami continue the percolation with Water. Distill the Alcohol from the first portion of the percolate, and evaporate the remain- der with the aqueous percolate to the consistence of an Extract. To this add 5 per cent, of its weight of Glycerin, and mix thoroughly. The dose is from % to 3 grains. 1021. Extractum Ergotae — Extract of Ergot. — The U. S. P. directs this to be made by evaporating Fluid Extract of Ergot to the consistence of a semi-solid extract by means of a water-bath at a temperature not exceed- ing I22°F. Ergotin is purified Extract of Ergot, made by evaporating 4 fl. ounces of Fluid Extract of Ergot by a water-bath to a syrupy consistence, and when cold mixing with 4 fl. ounces of Alcohol. After standing half an hour the alcoholic solution is filtered, and the filtered liquid evaporated to the consist- ence of a soft extract. This is usually called Bonjean's Ergotin. The dose is 2 to 5 grains. In solution it is used for hypodermic injections. 1022. Extractum Euonymi — Extract of Enonymus ( Wahod). — Exhaust Wahoo Bark with diluted Alcohol. Distill off the Alcohol, evaporate the remainder to the consistence of a solid extract, add 5 per cent, of its weight of Glycerin, and mix them thoroughly. 1023. Extractum Ferri Pomatum — Ferrated Extract of Apples — (Aepfclsai/rcs Eisc/icxtracf). — This is official in the G. P., and is made from Sour Apples, 50 parts converted to a pulp and expressed. To the expressed juice is added powdered Iron 1 part. The mixture is then heated on a water- bath as long as gas is evolved. The liquid is then diluted with 50 parts of Water and set aside. After several days it is filtered, and the filtrate evap- orated to a thick extract. This is much prescribed among the Germans. 1024. Extractum Gelsemium Alcoholicum — Alcoholic Extract of ' Gel- semium. — Gelsemium in fine powder is exhausted first with Alcohol 4 parts, and the percolation then continued with Water. The Alcohol is distilled from the first percolate until it is reduced to a soft extract, the aqueous percolate is then evaporated and mixed with the soft extract, and the whole is reduced to a pilular consistence. The dose is yi to 2 grains. 1025. Extractum Gentians — Extract of Gentian. — Gentian Root in very coarse powder is macerated in successive portions of boiling water, expressed, and the mixed liquids evaporated to a pilular consistence. The dose is from 2 to 10 grains. 1026. Extractum Glycyrrhizae Pura — Ptire Extract of Liquorice. Ex- haust Liquorice Root in coarse powder first with water in which 12 per cent, of the weight of the root of Water of Ammonia has been added, then with water until no more strength is perceptible. Heat the liquids obtained to boiling, then strain and evaporate by a water-bath to a solid extract. EXTRACTA — EXTRACTS. 447 Crude or common Extract of Liquorice is made by exhausting Liquorice with water and evaporating to an extract. 1027. Extractum Haematoxyli — Extract of Logwood. — Exhaust Log- wood with hot water, boil, strain, and evaporate the liquid to a solid extract. Dose 10 to 30 grains. 1028. Extractum Hyoscyami Alcoholicum — Alcoholic Extract of Hy- oscyamus. The U. S. P. directs recently dried Hyoscyamus leaves, which may be exhausted by means of the water-bath percolator by percolating first with 4 parts of a menstruum of two-thirds Alcohol and then with Water. The Alcohol is distilled from the first portion of the percolate and the residue together with the aqueous percolate evaporated by water-bath to pilular con- sistence. The dose is 5 to 10 grains. The Br. P. directs the juice of the fresh leaves to be obtained by bruising them and pressure, and evaporated, strained, etc., in the same manner as is directed (1002). 1029. Extractum Helenii — Extract of Inula {Elecampane). — Exhaust Inula in No. 40 powder by percolating in the water-bath percolator, first with Diluted Alcohol, then with water, distill the Alcohol from the first por- tion of the percolate and evaporate the residue with the remainder of the percolate by water-bath, to pilular consistence. The dose is from 2 to 15 grains. This is official in the G. P. 1030. Extractum Iridis — Extract of Iris {Blue Flag). — Exhaust the drug by water-bath percolation, first with Alcohol 4 parts, and then by per- colating with Diluted Alcohol. Distill off most of the Alcohol and evaporate the residue by means of a water-bath to pilular consistence. The dose is %. to 1 grain. U". S. 1031. Extractum Jaborandi — Extract of Jaborandi. — Percolate the drug in the water-bath percolator first with Alcohol 4 parts and then with until exhausted. Distill the Alcohol from the first percolate until only a soft extract remains, evaporate the aqueous percolate and, having mixed the extracts thus obtained, reduce them to pilular consistence. The dose is 2 to to grains. This extract is official in the Br. P. 1032. Extractum Jalapa— Extract of Jalap. — Exhaust Jalap by means of water- bait 1 percolation first with 4 times its weight of Alcohol and then with Water, distill the Alcohol from the first portion of the percolate until only a soft extracl remains, then evaporate the aqueous percolate, and having the two extracts thus obtained reduce them to pilular consistence. 'I he dose is from 5 to 15 -rains. This extract is official in the Br. I'. 1033. Extractum Juglandis — Extrac t of Juglans {Butternut Bark). — Exhaust the Bark of Butternul Root with Alcohol by means of water-bath ion, Distill off the Alcohol until the residue is reduced to a pilular consistence; to this add 5 per cent, of its weight of Glycerin and mix thor- oughly. The dose is 2 to 10 grains. 448 EXTRACTA — EXTRACTS. 1034. Extractum Krameriae — Extract of Rhatany. — Exhaust the Rha- tany Root by percolating in the water-bath percolater with hot water. Heat the percolate to boiling, strain and evaporate by a water-bath at a tempera- ture not exceeding 158 F. to dryness. The dose is from 5 to 20 grains. 1035. Extractum Lactucae — Extract of Lettuce. — The Br. P. directs this to be made from the fresh flowering herb of Lettuce, by bruising, ex- pressing the juice and evaporating, treating in the same manner as is directed ( 1002). The dose is from 5 to 15 grains. 1036. Extractum Leptandrae — {Extract of Leptandra Cu/vcrs Root). — Exhaust Leptandra by percolating in the water-bath percolator, first with a menstruum of two thirds Alcohol and then with water. Distill the Alcohol from the first portion of the percolate and evaporate the residue together with the aqueous percolate, by means of a water-bath to a pilular consistence, to this add 5 per cent, of Glycerin and mix thoroughly. The dose is 2 to 10 grains. 1037. Extractum Lupuli — Extract of Hop. — The hops are first perco- lated in the water-bath percolator with Alcohol, 4 parts, and then with water until exhausted. Distill the Alcohol from the first portion of the percolate and evaporate the aqueous percolate to a soft extract, mix the two extracts, and evaporate to a pilular consistence. The dose is 5 to 1 5 grains. This is official in the Br. P. 1038. Extractum Malti — Extract of Malt. — Exhaust coarsely ground Malt in a water-bath percolator with water heated to about 6o°C. (i40°F.) and as the percolate is received evaporate it by the heat of a water-bath not exceed- ing 6o°C. (i40°F.) until it is reduced to the consistence of a thick syrup. It is necessary in making this preparation to begin the evaporation at once as the percolate is received, and to continue it at a temperature as uniform as pos- sible until it is evaporated to the proper consistence, for upon this depends the preservation of the Diastase which is its important constituent. Extract of Malt is combined with many other preparations, which may be added to it in concentrated form. These combinations will be noticed under the head- ing Maltum, which see. 1039. Extractum Mezerei — Extract of Mezereum. — The U. S. P. directs an Alcoholic Extract, which may be prepared by exhausting Mezereum Bark in No. 30 powder, with Alcohol, by means of the water-bath perco- lator, and then distilling the Alcohol from the percolate until only a soft extract remains, and evaporating this by a water-bath to pilular consistence. The Br. P. directs an Ethereal Extract of Mezereon to be prepared in a similar manner as the above, but after being thus prepared, to dissolve the Extract in Ether and macerate with occasional agitation for 24 hours, then to decant the etherial solution, recover part of the Ether by distillation, and evaporate the remaining liquid to a soft extract. 1040. Extractum Nucis Vomicae — Extract of Nux Vomica. — Exhaust rasped or powdered Nux Vomica by percolating in the water-bath percolator EXTRACTA — EXTRACTS. 449 with a menstruum composed of 8 parts of Alcohol to i part of water. Distill off the Alcohol and evaporate the residue, by a water-bath, to a pilular con- sistence. The Br. P. directs an assayed Extract of Nux Vomica to be made which shall contain 15 per cent, of the total alkaloid. The dose is from % to 2 grains. The G. P. directs the Nux Vomica to be exhausted by digesting with diluted Alcohol, and the liquors to be evaporated to a dry extract. 1041. Extractum Opii — Extract of Opium. — Exhaust Opium by first macerating with boiling Water, until it is reduced to a pulp, then percolating with hot water in the water-bath percolator. Evaporate the percolate, strain and continue the evaporation until reduced to an extract, to which add 5 per cent, of Glycerin and mix thoroughly. The extract should contain about 20 per cent, of Morphine. The dose is l /i to 2 grains. 1042. Extractum Papaveris — Extract of Poppy. — Exhaust Poppy Cap- sules, freed from their seeds and in No. 20 powder, with successive portions of boiling water. Evaporate the liquors by a water-bath to a pint for each pound of the capsules used, to this add 2 fl. ounces of Alcohol, allow to stand 24 hours, then filter and evaporate the filtered liquid to pilular consistence. The dose is 2 to 5 grains. Br. P. 1043. Extractum Pareirae — Extract of Pareira. — Exhaust Pareira Root in Xo. 40 powder by percolating in the water-bath percolator with boil- ing Water, and evaporate the percolate by a water-bath to pilular consistence. The dose is from 10 to 30 grains. Br. P. 1044. Extractum Physostigmatis — Extract of Pkysostigma (Calabar Bean).— Exhaust Calabar Bean in No. 40 powder with Alcohol, by means of the water-bath percolator, and evaporate the percolate by distillation to the consistence of a pilular extract. The dose is ,',; to J grain. 1045. Extractum Podophylli — Extract of Podophyllum [Mandrake). — Exhaust Mandrake Root in No. 60 powder by percolating in a water-bath percolator first with a menstruum of 75 per cent. Alcohol, then with Water. Distill off the Alcohol from the first percolate and evaporate the residue with the remaining percolate to pilular consistence. The dose is ^ to 2 grains. 1046. Extractum Quassiae Extract of Quassia. — Exhaust Ouassia by means of a water-bath percolator with boiling Water, and evaporate the percolate by a water-bath to pilular consistence, to this add 5 per cent, of its weight of Glycerin and mix thoroughly. The dose is from 2 to 5 grains. 1047. Extractum Rhamni Frangulae — Exit -act of Frangula or Buck- tkorn Bark. — Exhaust Buckthorn Hark in No. 40 powder by percolating in a water-bath percolator, first with Diluted Alcohol and then with Water. Distill the Alcohol from the first portion <>i the percolate and evaporate the residue together with the remaining percolate to pilular consistence. Dose, 10 to 60 grains. 450 EXTRACTA — EXTRACTS. 1048. Extractum Rhei — Extract of Rhubarb. — Exhaust Rhubarb in No. 30 powder by percolating in a water-bath percolator first with Diluted Alcohol and then with water. Distill the Alcohol from the first portion of the percolate and evaporate the residue together with the remainder of the percolate by a water-bath, at a temperature not exceeding 70° C. (1 58 F.) to pilular consistence. The dose is from 5 to 15 grains. This may also be prepared by macerating with successive portions of Water and pressure, then evaporating the liquids as above. 1049. Extractum Rhei Compositum — Compo unci Extract of Rhubarb. — This is made according to the G. P. from — Extract of Rhubarb, 30 parts. Extract of Aloes 10 parts. Resin of Jalap, 5 parts. Medicinal Soap 20 parts. Rub them together, and, having moistened the mixture with Diluted Alco- hol, evaporate to a dry extract by means of a steam-bath. 1050. Extractum Sabinae — Extract of Savine. — Exhaust Savine with Diluted Alcohol by means of the water-bath percolator. Distill off the Alco- hol and evaporate the percolate, by a water-bath, to a thick extract. The dose is 2 to 15 grains. G. P. 1051. Extractum Scillae — Extract of Squill. — Macerate Squill with separate portions of Diluted Alcohol and express. Mix the liquids, distill off the Alcohol, and evaporate the residue to a thick extract. The dose is )/ 2 to 2 grains. G. P. 1052. Extractum Stramonii — Extract of Stramonium. — Exhaust Stra- monium Seed in No. 40 powder with diluted alcohol by percolating in the water-bath percolator. Distill the Alcohol from the percolate and evaporate the residue at a temperature not exceeding 50°C. ( 1 22°F.) by means of a water- bath to a pilular consistence. The dose is % to % grain. 1053. Extractum Taraxaci — Extract of Dandelion. — Fresh Dandelion Root, gathered in September, is cut fine, crushed in a mortar until reduced to a pulp, a little water added, and the juice expressed and allowed to deposit. It is then strained and heated to boiling, strained again and evaporated to pilular consistence. The dose is from 5 to 30 grains. 1054. Extractum Trifolii Fibrini — Extract of Buckbean. — Exhaust Buckbean with boiling water, strain and evaporate the liquid to a thick extract. This is official in the G. P. 1055. Extractum Tritici — Extract of Couch Grass. — Exhaust Triticum with boiling water, strain and evaporate the liquid to a thick extract. This is official in the G. P. under the name Extraction Graminis. 1056. Extractum Valerianae — Extract of Valerian. — Exhaust Vale- rian Root in No. 40 powder by percolating in the water-bath percolator with EXTRACTA DESTILLATA — DISTILLED EXTRACTS. 451 75 per cent. Alcohol, then with water. Distill the Alcohol from the first por- tion of the percolate, and evaporate the residue with the remainder of the percolate, by water-bath, at a temperature not exceeding 5o°C. (i22°F.) to a pilular consistence. Dose 2 to 20 grains. Although this extract is not official, it is more frequently used than many of those which are. 1057. Other Extracts. The foregoing Extracts, official in the U. S., Br. and German Pharmaco- poeias are all that are usually required. But a great number are quoted by manufacturing houses, and may be made by druggists in the same general manner as is directed for the Official Extracts, by using for exhausting the drug the same menstruum as is directed for making a fluid extract of the drug. EXTRACTA DESTILLATA — DISTILLED EXTRACTS. In American Pharmacy only two or three Distilled Extracts are known, and none are official ; but from the favor with which Distilled Extract of Witch Hazel has been received, it is evi- dent that many such Distilled Extracts might with advantage be made. In French Pharmacy under the name Alcoolats quite a large number of preparations made by distilling aromatic substances with a spiritous medium are known, and several of them are official. All drugs whose valuable medicinal properties are volatilized by the heat of boiling alcohol or water, and do not consist of essential oils which rise to the surface when cool, may be rep- resented in the form of Distilled Extracts. For making these Extracts the steam still, by which steam ma)- be forced tli rough the substances, is the best ; but for pharmaceutical use they may be distilled with the low shape still described on page 26 in the same manner as is directed on •; for distilling medicated waters from leaves, etc. A Wire-cloth basket should be suspended in the boiler in which the drugs should be placed to preserve the drug from too close contact with the heat. 4.V2 EXTRACTA DESTILLATA — DISTILLED EXTRACTS. A few formulas only are given as samples from which the druggist ma}- make any desired extract : 1058. Extractum Hamamelidis Destillatum. Distilled Extract Witch Hazel. Witch Hazel Leaves, fresh 2 pounds aw Water 1 gallon. Alcohol, 8 fl. ounces. Bruise the leaves in a mortar, pour the Alcohol upon them; put them in the still without the water-bath, add the Water and distill 2 pints. This may also be made by distilling with Water alone and then adding to the dis- tillate 25 per cent, of Alcohol. Distilled Extract of Horseradish, Scurvy Grass, Mustard, Nasturtium, Smartweed, and all other substances possessing like volatile principles, may be made in a similar manner. 1059. Extractum Buchu Destillatum. Distilled Extract Buchu. Buchu Leaves 1 pound av. Water 1 gallon. Alcohol, 8 fl. ounces. Moisten the Buchu leaves with the Alcohol and put them in the still with- out the water-bath, add the water and distill 2 pints. A great variety of similar aromatic dry substances may be treated in the same manner. 1060. Extractum Pruni Virginianse Distillatum. Distilled Extract Wild C Vierry. Wild Cherry Bark, of root, fresh 2 pounds av. Water 1 gallon. Alcohol, 8 fl. ounces. Bruise the bark, pour the Alcohol upon it and put in the still without the water-bath, pour the water upon it and distill 2 pints. This may also be made from the dry bark 1 pound, Alcohol 8 ounces, Water 1 gallon, and distill 2 pints, in the same manner as Extract Buchu. Other extracts of similar substances, whose virtues consist of volatile prin- ciples, may be made in the same manner. Alcoolats or Alcoholates. These are extracts made in a similar manner, but with a much larger proportion of Alcohol. Many substances con- EXTRACTA DESTILLATA. EXTRACTA FLUIDA. 453 taining essential oils are distilled with alcohol and represented in this manner. When made from the Oils they would be classed as spirits. The following formulae are examples. In French Pharmacy they are variously called Esprit or Eau without reference to their Alcoholic strength or composition : 1061. Alcoolat d'Absinthe. — Fresh leaves and tops of Wormwood 1,000 parts, Alcohol 80 per cent., 4,000 parts, distilled Wormwood water 1,000 parts. Let them macerate for 4 days, then distill by a salt water-bath, 2,500 parts. Alcoolats of Sweet Basil, Hysop, Lavender, Marjorum, Balm, Pep- permint, Spearmint, Sage, Thyme and other similar fresh substances are prepared in the same manner. 1062. Alcoolat d'Anis. — Aniseed 1 part, Alcohol 56 per cent., 5 parts, Let them macerate for two days then distill until all the Alcohol used is re- covered. Alcoolats of Caraway, Coriander, Fennel, Spice and other similar substances are prepared in this manner. 1063. Alcoolat de Cannelle (Cinnamon). — Cinnamon Bark ground fine 1 part, Alcohol 80 per cent., 5 parts. Let macerate 4 days then distill until all the Alcohol used is recovered. Alcoolats of Angelica, Calamus, Mace, Sassafras. Cloves, and a great variety of other strong aromatic substances are made in a similar manner. The foregoing formula: will be sufficient to show the general method of making the Alcoolats of French Pharmacy. Many more are known and used, but they are seldom called for in this country, and generally the simple spirits or essences of the substances will do when simple Alcoolats are desired ; of the compound Alcoolats so few are used here that it seems unnecessary to give their formulas. EXTRACTA FLUIDA FLUID EXTRACTS. Fluid extracts arc of American origin, and our Pharma- copoeia is tin- only one which recognizes preparations by this i), line Tin: British Pharmacopoeia has a few " Liquid Ex- tracts," some of which are similar to Fluid Extracts, bu1 this clas-, of preparations may he claimed as distinctly .American. Fluid Extracts aim to represent tin- entire soluble medicinal constituents of a certain weight of drug in an equivalent fluid 454 EXTRACTA FLUIDA — FLUID EXTRACTS. measure. As such, they are the most convenient of the galenicals, for they may be used in place of the drugs them- selves in making many preparations extemporaneously that would otherwise require considerable time to prepare. They are also very convenient to prescribe, as the dose is the same as of the powdered drug or substances from which they are prepared. Since the introduction of Fluid Extracts, some forty years ago, many methods for making them have been proposed, all having in view the same object, viz.: To represent the entire medicinal value of a specified weight of the drug in an equiva- lent quantity of Fluid Extract. While in main, this may readily be done, yet it must be borne in mind that the entire medicinal value of some drugs cannot be held in solution in an equivalent fluidmeasure of Fluid Extract, by the menstruums usually employed for making them. A brief description of the principal methods which have heretofore been employed for making Fluid Extracts, is given for the convenience of our readers, but the process of water- bath percolation presents great advantages over any other, and is therefore employed in the formulae for the preparations. It is, in fact, the only process by which first-class fluid extracts can be made economically, in a small way, by druggists. The value of a fluid extract depends upon the amount of active medicinal agent that it contains, and the formulae given are designed to best secure that end, without producing prep- arations loaded with inert and worthless extractive matter as is often the case with those furnished by manufacturers. The formulas are each calculated to make a pint of fluid extract, but larger quantities may be made somewhat more advantageously. In making large quantities it may not be necessary to con- tinue the heat so long as is directed, as the water-bath will retain its heat for some time, when once heated. When Fluid Extracts are used for making Tinctures, Infu- sions, Syrups, etc., fluidmeasure equivalent to the weight of the drug, or drugs directed, may be used. Solid extracts may be made from nearly all the fluid extracts by evaporating them to the proper pilular consistence. EXTRACTA FLU IDA — FLUID EXTRACTS. 455 The following are the principal popular methods that have been employed or directed for making fluid extracts : 1064. U. S. 1870 Process. "The quantity of powdered material directed to be used is 16 troyounces. This powder is to be moistened with a specified quantity of menstruum, and properly packed in a suitable percolator. The surface of the powder is then to be covered with a disc of paper, and the remaining portion of 16 fluid- ounces of menstruum is to be poured upon it. When the liquid begins to drop from the percolator, close the lower orifice with a cork, and, having closely covered the percolator to prevent evaporation, set it aside in a moderately warm place for four days. " The cork is then to be removed, more menstruum is to be gradually poured on, and the percolation continued until 24 fluidounces have been ob- tained. Of these, the first 14 fluidounces are to be reserved, and the remainder having been carefully evaporated to two fluidounces, is to be mixed with the reserved portion, and filtered through paper if necessary." The quantity of drug directed in the 1870 formulas is about 5 per cent, more than the equivalent fluid measure of the fluid extract obtained, the difference being the same as between troyweight and fluid measure. 1065. U. S. 1880 Process. No general formula is given in the 1880 Pharmacopoeia for making fluid extracts, each drug having a detailed formula for itself ; but from them the following general formula may be deduced: 100 grammes of the powdered material directed to be used are moistened with from 30 to 50 grammes of menstruum (according to the nature of the drug;, and properly packed in a suitable percolator; enough menstruum is then added to saturate the powder, and leave a stratum above it. When the liquid begins to drop from the percolator, the lower orifice is closed, the per- colator covered, and its contents allowed to macerate for 48 hours. The stopper is then loosened, and the percolation allowed to proceed gradually, adding first the remainder of 100 grammes of the menstruum, which has not previously been used, and then more menstruum, as is directed in the formula until the drug is exhausted. The first 85 cubic centimetres of the percolate received are reserved and, by means of a water-bath and still the Alcohol is recovered from the remainder, and the residue evaporated to a soft extract ; this soft extract is then dissolved in the reserved portion, and enough menstruum (as is directed in the formula) added to make the fluid extra* t measure 100 cubic centimetres. Fluid extracts made by this process r< present the medicinal value of a gramme of a drug in a cubic centimetre, therefore the weight of the drug and fluid measure of the fluid extract are equivalent. 456 EXTRACTA FLUIDA — FLUID EXTRACTS. 1066. Repercolation Process. The following is an abstract of Squibb's method of Fractional or Reper- colation. This process is probably the best cold process in use, but it is too tedious to be generally employed by druggists ; some skill and experience are required to use it successfully : To make 3 pints of a fluid extract take of The required drug, or drugs, in powder as directed, 50 ounces av. The required menstruum as directed, a sufficient quantity. First. — Take )■< of the powder (16% ounces avoir.) and 3 pints of the menstruum required. Moisten the powder with from 6 to 8 fl. ounces of the menstruum, pack it properly in a suitable percolator, pour upon it suf- ficient menstruum to saturate the drug and leave a stratum above it, and when the percolate begins to drop, close the lower orifice and allow to macerate from two or three days ; then begin to percolate, adding the remainder of the menstruum (and more if necessary) to the powder, con- tinuing the percolation until the drug is exhausted, receiving the percolate as it passes in the following manner : Reserve the first 12 fl. ounces mark a. the next 6 fl. ounces mark b. the next 8 fl. ounces mark c. the remainder of the percolate, mark d. The last portion, d, is a variable quantity, but should be from 20 to 30 rl.ounces. With some drugs this may be forced through by adding water through the percolator, while with others the same menstruum must be used throughout. Second. — Take yi more of the powder (165^ ounces avoir.) as before, moisten it with the portion of percolate marked b, pack as before, pour upon it the percolate marked c, and afterward sufficient of the percolate marked d and sufficient fresh menstruum to exhaust the drug, receiving the percolate as follows . Reserve the first 16 fl. ounces mark e. the next 6 fl. ounces mark/". the next 8 fl. ounces, mark £-. the remainder of the percolate, mark h. The last portion, h, is a variable quantity, but should be from 16 to 20 rl.ounces. With some drugs it may be forced out with water, while with others the same menstruum should be used throughout. Third. — Take the remaining '/$ i l ^> z A ounces avoir.) of the powder; moisten it with the portion marked /, pack as before, pour upon it the portion marked g, and afterward sufficient of the percolate marked // to saturate the powder and leave a stratum above; allow to macerate and EXTRACTA FLUIDA — FLUID EXTRACTS. 457 percolate as before, adding the remainder of the percolate marked // and sufficient fresh menstruum to exhaust the drug, receiving the percolate as follows : Reserve the first 20 fl. ounces mark /. the remainder of the percolate, mark j. Lastly. — Mix the reserved portions, a, e and i, which constitute the fluid extract and reserve the last portion j, to moisten and percolate the next batch of drugs to be made into fluid extract of the same kind, marking it repercolate of the drug or drugs from which the fluid extract was prepared. 1067. Pressure Process. The following is an abstract of N. Spencer Thomas's method of extracting the strength of drugs by maceration and pressure : Although this process does not entirely exhaust the medicinal strength of the drugs, it produces better extracts than most that are in the market. First. — Take 16^ ounces avoir, of the drug, of the proper fineness, and menstruum sufficient. Moisten the drug with from 8 to 12 fl. ounces of the menstruum (according to the nature of the drug), and set aside in a wide- mouth jar, or suitable covered vessel. Allow to stand four days, then press out as much as possible with a tincture press, and reserve the product. Second. — Moisten the same drug, as before, with from 6 to 8 ounces of the menstruum. Allow to stand, and press out as before, adding the product to the portion before reserved. Third. — Repeat the second operation, adding the product to the portions before reserved. Fourth. — Repeat the second operation, but so regulate the last amount of menstruum added as to make 1 pint of the fluid extract when added to the portions before reserved. Filter, if necessary. When this process is employed the drugs should be inclosed in a coarse, canvas cloth or bag before putting in the press. The pressure should be gradual and long continued, that the moisture may be as nearly as possible extracted from the drugs. A 1 -gallon tincture press will answer very well for making from 1 to 3 pounds of fluid extract. Combination Process — Repercolation and Pressure. — A combination of the Repercolation and Pressure process is used by some manufacturers. The percolation is conducted the same as is directed for repercolation, except that the last portions, d, h and /, are obtained by pressure instead of by percolation. It is more economical than repercolation alone, as there is no loss of menstruum in the last part of the percolations, which is quite an important item of the expense of the Fluid Kxtracts. 458 EXTRACTA FLUIDA — FLUID EXTRACTS. 1068. Fluid Extracts by Water-Bath Perco- lation. To give a detailed formula for every Fluid Extract which is made or known on the market, would require a large volume, and, indeed, it is unnecessary, for they may be classed accord- ing to the nature of the drug employed, and a few formulas will represent them all, it being necessary only to insert the name of the drug in the specified formula to adapt it to the particular Fluid Extract being made. The drugs from which Fluid Extracts are made are there- fore divided as far as is practicable into Classes, and a general formula given which is suited to the nature of the drugs in each Class. The formulae given are by water-bath percolation, which, as previously explained, is considered the best process for making Fluid Extracts. Other processes, however, maybe employed by using the menstruum designated for the drug, and proceeding as is directed in the process. Full detailed formulae for all the official Fluid Extracts will be found in Fenner's Working Formul/E. Fluid Extracts, Class A. In this class are included all Fluid Extracts made from drugs requiring Alcohol as a menstruum, except such as require special treatment or manipulation. To complete the formula for any Fluid Extract in this class, put the name of the drug and the fineness of the powder in the following 1069. General Formula. The Drug in No. powder, . . . 16 f< ounces av. Alcohol, a sufficient quantity. Moisten the powder with from 6 to 8 fl. ounces of Alcohol, pack firmly in the water-bath percolator, pour upon it enough Alcohol to saturate and cover the drug and set in a warm EXTRACTA FLUIDA — -FLUID EXTRACTS. 459 place for two days ; then heat very moderately, and after one hour begin to percolate slowly, adding Alcohol to the drug, and continuing the heat and percolation until 14 fl. ounces have passed, which reserve. Turn off the heat and continue the percolation with Alcohol until the drug is exhausted. Distill the Alcohol from this last portion of the percolate until only 2 fl. ounces remain, which add to the reserved portion to make a pint of the Fluid Extract. Lastly, after standing a few days filter through paper or muslin, adding enough Alcohol through the filter to make the measure a pint. If Glycerin is directed to be used it should be added to the first portion of the menstruum used. The Alcohol remaining in the drug after percolation may be recovered by distillation. The star ( * ) before a formula denotes that a Fluid Extract is also made from the green plant. See Green Plant Fluid Extracts. U. S. Official Fluid Extracts. The following are the U. S. Official Fluid Extracts made with Alcohol in accordance with this formula: 1070. Extractum Aconiti Fluidum — Fluid Extract of Aconite. — Aconite Root in No. 60 powder — Alcohol. Make a fluid extract as directed O069), and add 30 grains Tartaric Acid to a pint. 1071. Extractum Aromaticum Fluidum — Aromatic Fluid Extract. — Aromatic powder — Alcohol. Make a fluid extract as directed (1069). 1072. Extractum Belladonna Fluidum — Fluid Extract of Belladonna Root. — Belladonna Root in No. 60 powder — Alcohol. Make a fluid ex- tract as directed (1069). For Fluid Extract Belladonna Leaves see Class C. 1073. Extractum Brayerae Fluidum — Fluid Extract of Kousso. — Kousso Flowers in No. 40 powder — Alcohol. Make a fluid extract as directed ( 10691. 1074. Extractum Calami Fluidum — Fluid Extract of ( alamus (Sweet Flag), -Calamus in No. 50 powder — Alcohol. Make a fluid extract as llllr. ted I I069). 1075. Extractum Cannabis Indicae Fluidum — Fluid Extract of Indian Cannabis or Indian Hemp. — Cannabis in No. 20 powder — Alcohol. Make a fluid extract as directed 1 1 069). 460 EXTRACTA FLUIDA — FLUID EXTRACTS. 1076. Extractum Capsici Fluidum — Fluid Extract of Capsicum {Cayenne Pepper). — Capsicum in No. 60 powder — Alcohol. Make a fluid extract as directed ( 1069). 1077. * Extractum Cimicifugae Fluidum — Fluid Extract of Cimici- fuga {Black Cohosh). — Cimicifuga in No. 50 powder — Alcohol. Make a fluid extract as directed (1069). The British Liquid Extract of Cimicifuga is identical with this. 1078. Extractum Cubebae Fluidum — Fluid Extract of Cubeb. — Cubeb in No. 60 powder — Alcohol. Make a fluid extract as directed (1069). 1079. * Extractum Cypripedii Fluidum — Fluid Extract of Cypri- pedium {American Valerine, Nervine). — Cypripedium in No. 60 powder — Alcohol. Make a fluid extract as directed (1069). 1080. * Extractum Gelsemii Fluidum — Fluid Extract of Gelsemium {Yelhtu /asmino. — Gelsemium in No. 60 powder — Alcohol. Make a fluid extract as directed (1069). 1081. * Extractum Gossypii Radicis Fluidum — Fluid Extract of Cotton Root. — Gossypium (Cotton Root Bark) in No. 30 powder, 16^ ounces av., Glycerin 4^ ft ounces, Alcohol a sufficient quantity. Percolate first with the mixed Glycerin and Alcohol, then with Alcohol as directed (1069). 1082. Extractum Lupulinae Fluidum —Fluid Extract of Lupulin.— Lupulin — Alcohol. Make a fluid extract as directed (1069). 1083. Extractum Mezerii Fluidum — Fluid Extract of Mezereum (Mezereon). — Mezereum in No. 30 powder — Alcohol. Make a fluid extract as directed (1069). 1084. Extractum Sabinae Fluidum — Fluid Extract of Savin. — Savin (tops) in No. 40 powder — Alcohol. Make a fluid extract as directed (1069). 1085. Extractum Sanguinariae Fluidum — Fluid Extract of Sangut- naria 1 Bloodrooi). — Sanguinaria in No. 50 powder — -Alcohol. Make a fluid extract as directed (1069). 1086. Extractum Scillae Fluidum— Fluid Extract of Squill. — Squill in No. 20 powder — Alcohol. Make a fluid extract as directed (1069). 1087. -'Extractum Veratri Viridis Fluidum — Fluid Extract of I'era- trum I'iridc {American Hellebore). — Veratrum Viride in No. 60 powder — Alcohol. Make a fluid extract as directed (1069). 1088. Extractum Xanthoxyli Fluidum — Fluid Extract of Xanthoxy- luni {Prickly Ash). — Xanthoxylum (Prickly Ash) in No. 40 powder — Alcohol. Make a fluid extract as directed ([069). 1089. Extractum Zingiberis Fluidum — Fluid Extract of Ginger. — Ginger in No. 40 powder — Alcohol. Make a fluid extract as directed (1069). EXTRACTA FLITDA — FLUID EXTRACTS. 461 Unofficial Fluid Extracts. The following are unofficial Fluid Extracts which require Alcohol as a menstruum for preparing them, and are made in the same manner as directed (i< UNOFFICIAL FLUID EXTRACTS CLASS A. LATIV NAME. COMMON NAME. IO9O IO9I IO92 IO93 IO94 IO95 1096 IO97 IO9S IO99 1 1 OO IIOI 1 102 1103 1104 1 105 1 106 1 107 110S 1 109 1 1 10 in 1 1 1 12 1113 1114 1115 1 1 16 1.17 1118 UK; 1 1 20 I 121 1122 1123 I I24 1125 I [26 I I 27 1 1 28 I I2<; ll/. 1131 1132 1133 Acta-a alba Acta-a rubra Agaricus albus Akasga Alkanna (Anchusa) Alstonia constricta Alstonia scholaris Angelica officinalis Apium graveolens Asarum Canadense Asclepias cornuti Asclepias incarnata *Asclepias tuberosa Aspidium (Filix Mas). . . . A vena Sativa Azederach (melia A.). . . . *Baptisia tinctoria Boldus (Peumus B.) Boletus Laricis Bryonia alba Canella alba *Cannabis sativa Cantharis vesicatoria. . . . Capsella, B'a pastoris . . . Cardamomum Carophyllus *Cereus Chenopodium Cinnamomum Cocculus Indicus Convallaria Majalis Coriandrum Curcuma longa Delphinum consolida. . . . Delphioum Staphisagria. Dioscorea villoma Dipterix odorata Dita (Alst'a scholaris). . . 1 frosera Drimys Winteria Erechthites hieracif'a. . . . Icnse • : Eriodictyon •Euphorbia corollata White Cohosh Baneberry, red White Agaric Boundon, Ikaju, Quai. . Alkanet Australian Bitter Bark. . Dita Bark Angelica Celery Canada Snakeroot Silkweed White Indian Hemp. . . . Pleurisy, or White Root. Male Fern Common Oats Bride of India or China. . Wild Indigo Boldo Agaric Bryony, White Canella American Hemp Cantharides Shepherd's Purse Cardamom Cloves Cactus Wormseed Cassia or Cinnamon. . . . Fish lorries Lily of the Valley Coriander Turmeric Larkspur Stavesacre Wild Nam Tonka, Tonqua.orT. Bean Dita Bark Sundew Winter's Bark Fireweed » lanada Fleabane Verba Santa Large Flowering Spurge Powder No. Root 60 Root I 60 Fungus .... 40 Root j 60 Root , 50 Bark '• 60 Bark j 60 Root 60 Seed j 60 Root I 60 Root 60 Rcot 60 Root 60 Root 60 Seed ! 40 Root bark. . 60 Root 60 Leaves 50 Fungus ... 40 Root 60 Bark j 60 Plant 50 Whole fly... 60 Herb 50 Seed 60 Flower buds 60 Plant 50 Seed 00 P.ark Oo fruit I 60 Rootorflow's do Fruit 60 Rhizome ... (>o Seed Oo Seed 60 Rhizome. ... 60 Seed 60 P.ark 60 Herb 40 Bark 60 Herb 40 Herb 40 Leaves 50 Root ' 60 462 EXTRACTA FLUIDA — FLUID EXTRACTS. UNOFFICIAL FLUID EXTRACTS CLASS A — Continued. LATIN NAME. COMMON NAME. Powder No. Filix Mas(Aspid'm)... Galanga Gillenia stipulacea. . . . Gillenia trifoliata Guaiacum lignum Helonias Hibiscus Abelmos's. . . Humulus Hyoscyami semen. . . . Ignatia Imperatoria Ins Elorentina Jalapa (Ipomea J'a)... Kamala (Rottlcra) Kava (Methisticum). . . Levisticum Lindera Liquidambar Lippia Mexicana Liriodendron ^Lobelia Magnolia glauca Methysticum Micr meria Myrica cerefera. . Myristica fragrans. . . . Petroselinum. ....... Peumus Boldus Phelandrium Physostigma P menta Piper Methysticum . . . Piper Nigrum Pimpinella saxifraga. . . *Popu!us Candicans. . . . Pyrethrum *Rhus Toxicodendron. . Ricinus Rottlera; glandulae. . . . Sabadilla Santalum citrinum. . . . Santalum rubrum. . . . Santonica Silphium lacinatum... Staphisagria (Del. S.). Strychnos Ignatia. . . . | Sumbul (Ferula S.).. . . *Thuja occidentalis. . . . i Trillium pendulum. . Turnera aphrodis'ca. . . Urechites suberecta.. . Veratrum sabadilla. . . Wintera (Drimys W.). Xanthoxylum Zedoaria Male Fern Galangal (Catarrh Root). American Ipecac Indian Physic Guaiac False Unicorn : Amber or Ambrette. . . . j Hops i Henbane Ignatia Bean Masterwort Orris Root Jalap Kameela Ava Kava Lovage Spicewood, Fever Bush. Sweet Gum Tree Tulip Tree, Whitewood. Lobelia, Indian Tobacco Magnolia Ava Kava, Kava Kava. . Verba Buena Bayberry Mace or Nutmeg Parsley Seed Boldo Water Fennel Seed Calabar Bean Allspice Ava or Kava Kava Black Pepper Pimpernel, Small Saxifrage Balm or Balsam of Gilead Pellitory ; Poison Ivy or Oak Castor Oil Bean (Kamala) Kameela Cevadilla i White or Yellow Santal. Red Saunders Wormseed, unexpanded. Rosin weed Stavesacre Ignatia Bean Musk root I Arbor Vita-, Thuya, Beth or Birth Root Damiana Cevedilla Winter's Bark Prickly-Ash Berries Zedoary Root Rhizome. . .. Root Root Wood Root Seeds Flowers .... Seed Seed Rhizome. . .. Rhizome.. .. Tuber Glands, etc. Root Root or seed Bernesorb'k Bark Herb Bark Seed Flowers or b Root Plant Bark Seed Fruit Leaves Fruit Seed Fruit Root Fruit Root Leaf buds. . Root Leaves Seed Glands, etc. Seed Wood Wood Flower heads Root Seed. . . Seed .... Root Twigs . . Root 1 eaves . . Leaves . . Seed. . . . Bark.... f-ruit.. . . Root EXTRACTA FLUIDA — FLUID EXTRACTS. 463 Fluid Extracts Class B. The following drugs require a menstruum of three measures of Alcohol to one measure of Water for preparing their Fluid Extracts. To complete the formula for any Fluid Extract in this class put the name of the drug and the fineness of powder required in the following 1 189. General Formula. The Drug, in No. powder, . . 16% ounces av. Alcohol, I , rr ■ ' - each, a sufficient quantity. Water, ) 4 y Mix three measures of Alcohol with 1 measure of Water, and having moistened the drug with from 8 to 10 ounces of the mixture, macerate for 24 hours in a covered vessel in a warm place ; transfer to the water-bath percolator, pack firmly, pour upon it sufficient menstruum to saturate and cover the drug and set in a warm place for two days ; then heat mod- erately and after one hour begin to percolate slowly, adding menstruum to the drug and continuing the heat and percolation until 13 ounces have passed, which reserve. Turn off the heat and continue the percolation with the menstruum until the drug is exhausted. Distill the Alcohol (^ of the measure) from this last portion, evaporate the residue to a soft extract, which dissolve in the reserved portion and add enough of the menstruum to make a pint of the Fluid Extract. The Alcohol remaining in the drug after percolation may be recovered by distillation. If Glycerin is directed it should be added to the fust portion of the menstruum used. The * indicates that Fluid Extracts are also prepared from the fresh or green drug. See Green Plant Fluid Extract. Many of the drugs that are included in Class A yield their medicinal properties to a menstruum of 3 parts Alcohol to 1 of Water, and might properly be included in this class, but as the\- have generally been made with Alcohol only as a men- struum we have not thought best to depart from the estab- lished custom for the small saving that would be made. 4(54 EXTRACTA FLUIDA — FLUID EXTRACTS. U. S. Official Fluid Extracts. The following are the U. S. Official Fluid Extracts, requir- ing a menstruum of 3 parts by weight of Alcohol to 1 of Water. They may, however, be made by the general formula ( 1189), using 3 measures of Alcohol to I of Water. 1190. *.Extractum Grindeliae Fluidum — Fluid Extract of Grindelia. — Grindelia in No. 30 powder. — Alcohol 3, Water 1. Make a fluid extract as directed (11891. 1 191. Extractum Guaranae Fluidum — Fluid Extract of Guar ana.— Guarana in No. 50 powder. — Alcohol 3, Water 1 . Make a fluid extract as directed ( 1189). 1 192. Extractum Hydrastis Fluidum — Fluid Extract Hydrastis {Golden Seal). Hydrastis in No. 50 powder. — Alcohol 3, Water 1. Make a fluid extract as directed (4 189). 1 193. * Extractum Iridis Fluidum — Fluid Extract of Iris {Blue Flag). Iris (Blue Flag Root) in No. 50 powder. — Alcohol 3, Water 1. Make a fluid extract as directed ( 1 189). 1 194. Extractum Nucis Vomica? Fluidum — Fluid Extract lYux Vomica. — Nux Vomica in No. 60 powder. — Alcohol 8, Water 1. Make a fluid extract as directed (1189). The official formula directs a menstruum of 8 parts by weight (9 by mea- sure) of Alcohol to 1 part of Water. This formula is included in this class, but the menstruum as here directed should be used. 1 195. Extractum Podophylli Fluidum — Fluid Extract of Podophyllum (Mandrake). — Podophyllum (Mandrake Root) in No. 50 powder. — Alcohol 3. Water 1. Make a fluid extract as directed (1189). 1 196. Extractum Serpentariae Fluidum — Fluid Extract of Serpen- taria. — Serpentaria in No. 50 powder. — Alcohol 3, Water 1. Make a fluid extract as directed (1189). P'luid Extracts of Digitalis, Hyoscyami/s, Rhubarb and Stramonium, are directed by the U. S. P. to be made with 3 parts by weight of Alcohol to 1 of Water, but in our opinion their properties are as well obtained by a men- struum of less Alcoholic strength, and we have put them in Class C. Some of the fluid extracts included in this class might be made with a menstruum of less alcoholic strength, but it is rather difficult to direct the exact proportion of Alcohol which would be necessary to hold the medicinal properties of the drugs, as they are found in the market, in solution ; there- fore, it is best to have the menstruum contain an excess rather than a deficiency of spirit. EXTRACTA FLUIDA — FLUID EXTRACTS. 465 Unofficial Fluid Extracts. The following are unofficial Fluid Extracts which require 3 measures of Alcohol to I measure of Water as a menstruum for preparing them, and are made in the same manner as directed (i 189) : UNOFFICIAL FLUID EXTRACTS CLASS B. LATIN NAME. COMMON NAME. 1 197 Acalypha Virginica 1 198 Anemopsis Californica. . .. 1 199 *Arum triphyllum 1200 Asimina triloba 1201 Aspidosperma 1202 *Baccharis pilularis 1203 '•■"Calycanthus Floridus 1204 Cascarilla(Croton Eluteria) 1205 Cochlearia armoracia 1206 Coto (add 4 fl. oz. Glycerin) 1207 Eremocarpus Setigerus. . . 1208 Erythrophlctum, Casca. . . 1209 Ephedra Antisyphilitica. . 1210 Euphorbia Ipecacuanha. ..[ 1211 Euphorbia pilulifera 1212 *Grindelia squarrosa j 1213 Juglans cinerea 1214 Menispermum 1215 Mercurialis annua 1216 Nectandra 1217 ''Polygonum 1218 *Polymnia uvedalia 1 2 19 Sassafras officinalis 1220 ^Stramonium (Datura S.). . Mercury Weed Yerba Mansa Wild or Indian Turnip. Quebracho Kidney Root Carolina Allspice Cascarilla Horseradish Coto Bark Ginger Leaf Sassy or Mancona. . . . Ephedra Ipecacuanha Spurge. . Pill Bearing Spurge. . American Butternut. Yellow Parilla Mercury Herb Bebeeru Smartweed Bearsfoot, Leafcup. . Sassafras Stramonium Part Used. [^ Herb 40 Plant \ 40 Cormus . . . 50 Seed I 50 Bark 50 Root 50 Bark 50 Bark | 50 Root 50 Bark 50 Herb 40 Bark. ; 50 Plant j 50 Root 50 Plant 40 Leaves, tops 40 Root bark. . . 50 Root 50 Herb 40 Bark 50 Herb 30 Root 50 Root bark... 50 Leaves 1 40 Fluid Extracts, Class C. The following drugs require a menstruum of two measures of Alcohol to one measure of Water, for preparing their Fluid Extracts. To complete the formula for any Fluid Ex- tract in this Class, put tin: name of the drug and the fineness of powder required in the following 1221. The Drug Alcohol, / Water, i General Formula. in No. powder i < i ' j < lunces av. each, a sufficient quantity. 466 EXTRACTA FLUIDA — FLUID EXTRACTS. Mix two measures of Alcohol with one measure of Water, and having moistened the drug with from 8 to 10 ounces of the mixture, macerate for 24 hours in a covered vessel in a warm place ; transfer to the water-bath percolator, pack firmly, pour upon it sufficient menstruum to saturate and cover the drug, and set in a warm place for two days ; then heat moder- ately, and after one hour begin to percolate slowly, adding menstruum to the drug, and continuing the heat and percola- tion until 13 ounces have passed, which reserve. Turn off the heat and continue the percolation with the menstruum until the drug is exhausted. Distill the Alcohol {-A, of the measure) from this last portion, evaporate the residue to a soft extract, which dissolve in the reserved portion, and add enough of the menstruum to make a pint of the fluid extract. The Alcohol remaining in the drug after percolation may be recovered by distillation. If Glycerin is directed it should be added to the first portion of menstruum used. The " :: " indicates that fluid extracts are also prepared from the fresh or green drug. See Green Plant Fluid Extract. U. S. Official Fluid Extracts. The following U. S. Official Fluid Extracts are directed by the U. S. P. to be made with a menstruum of Alcohol 2 parts by weight to Water 1 part, but they may be made by the gen- eral formula (1221), using Alcohol 2 parts by measure to Water 1 part. 1222. Extractum Aurantii Amari Fluidum — Fluid Extract of Bitter Orange Peel. — Bitter Orange Peel in No. 20 powder — Alcohol 2, Water 1. Make a fluid extract as directed (1221). 1223. Extractum Buchu Fluidum — Fluid Extract of Buchu. — Buchu in No. 40 powder — Alcohol 2, Water 1. Make a fluid extract as directed (1221). 1224. Extractum Colchici Radicis Fluidum — Fluid Extract of Col- chicum Root. — Colchicum Root in No. 50 powder — Alcohol 2, Water 1. Make a fluid extract as directed (1221). 1225. Extractum Colchici Seminis Fluidum — Fluid Extract of Col- chic u»i Seed. — Colchicum Seed in No. 30 powder — Alcohol 2, Water 1. Make a fluid extract as directed (1221). EXTRACTA FLUIDA — FLUID EXTRACTS. 467 1226. Extractum Digitalis Fluidum — Fluid Extract of Digitalis {Foxglove). — Digitalis (recently dried) in No. 50 powder — Alcohol 2, Water 1. Make a fluid extract as directed (1221 ). 1227. Extractum Hyoscyami Fluidum — Fluid Extract of Hyoscyamus (Henbane). — Hyoscyamus in No. 50 powder — Alcohol 2, Water 1. Make a fluid extract as directed (1221). 1228. Extractum Matico Fluidum — Fluid Extract of Matico. — Matico in No. 40 powder — Alcohol, Water, Glycerin. Mix 14 fl. ounces of Alcohol 3 fl.ounces each Water and Glycerin for first percolation, then finish with Alcohol 2, Water 1, as directed ( 1221 1. 1229. Extractum Rhei Fluidum — Fluid Extract of Rhubarb. — Rhu- barb in No. 30 powder — Alcohol 2, Water 1. Make a fluid extract as di- rected (1221). 1230. Extractum Rubi Fluidum — Fluid Extract of Rubus {Black- berry). — Blackberry Root-Bark in No. 50 powder — Alcohol, Glycerin, Water. Mix 8 fl.ounces Alcohol, 5 fl.ounces of Water and 1% fl.ounces of Glycerin for first percolate, then finish with a menstruum of 26 fl.ounces Alcohol to 16 fl.ounces of Water. 1231. Extractum Senegae Fluidum— Fluid Extract of Senega. — Se- nega in No. 40 powder — Alcohol 2, Water 1, Water of Ammonia. Make a fluid extract as directed (1221), and when completed add 3 fl. drachms Water of Ammonia to a pint. 1232. Extractum Stramonii Fluidum — Fluid Extract of Stramo- nium. — Stramonium in No. 40 powder — Alcohol 2, Water 1. Make a fluid extract as directed (1221). 1233. Extractum Valerianae Fluidum — Fluid Extract of Valerian. — Valerian in No. 50 powder — Alcohol 2, Water 1. Make a fluid extract as directed (1221). 1234. ••Extractum Viburni Fluidum — Fluid Extract of Viburnum. — Viburnum (Black Haw) in No. 50 powder — Alcohol 2, Water 1. Make a fluid extract as directed (1221). Fluid Extract of Digitalis, Hyoscyamus, Rhubarb and Stramonium, are directed by the l. S. P. to be made with a menstruum of 3 parts Alcohol by weight to 1 part Water, but we have classed them here, as we think the alcoholic strength of the menstruum sufficient. Many of the fluid extracts included in this class might readily be made with diluted Alcohol instead of 2 parts of Alcohol to 1 part of Water but for the difficulty experienced in percolating with the weaker menstruum, on account of the larger proportion of water softening their mucilaginous con- stituents, thus making it impossible for the menstruum to pass through them. It is therefore necessary in exhausting them to use a menstruum of sufficient alcoholic strength to prevent this difficulty and allow the percolation to 468 EXTRACTA FLUIDA — FLUID EXTRACTS. proceed freely. Some manufacturers first exhaust these drugs with an alco- holic menstruum and then distill off a portion, making up the quantity with water, but this is hardly expedient in making small quantities. Unofficial Fluid Extracts. The following are unofficial Fluid Extracts which require 2 measures of Alcohol to I measure of Water for preparing them, and are made in the same manner as is directed (1221): UNOFFICIAL FLUID EXTRACTS CLASS C. No. LATIN NAM?:. COMMON NAME. Powder No. 1235 Acacia jurema Adstringens Bark 50 1236 Aconiti folia Aconite, Monkshood ... Leaves ! 30 1237 .Esculus glabra Buckeye Bark 40 123S .Esculus Hippocastanum. Horse Chestnut : Seed 40 1239 *Ailanthus Tree of Heaven ' Root bark. . . 40 1240 Adansonia digitata I Baobab i Bark 40 1241 Alnus rubra (or Serrulata) . j Tag Alder Bark 40 1242 Althsese radix Marsh Mallow Root 20 1243 Anemopsis Californica. . . Herba Mansa Root 40 1244 Anethum graveolens Dill Seed Fruit 40 1245 Angostura (Galip'cuspora). Angustura Bark 50 1246 Anisum Anise Seed Fruit | 40 1247 Apocynum androsiu'um. . . Bitter Root Root \ 50 1248 Apocynum cannabinum. . . Black Indian Hemp. . . . Root j 50 1249 Arnica; flores j Arnica Flowers Flowers 30 1250 Artemisia frigida Mountain Sage Plant 30 1251 Artemisia vulgaris Mugwort Root 40 1252 Asclepias curassavica Blood Flower Plant j 30 1253 Belladonna? folia , Belladonna Leaves j 30 1254 " : "Berberis aquifolium Oregon Grape Root 50 1255 Berberis vulgaris Barberry Bark 50 1256 Betonica officinalis Betony Herb 30 1257 Buxus sempervirens Box j Barkorl'v's. 30 1258 Calendula Marigold Flowers 30 1259 Carum carvi j Caraway Seed Fruit I 50 1260 Carrota (Dancus C.) Carrot Seed Fruit .. 50 1261 Catalpa (Bignonia C.) ... Cigar Tree Bark, pods.. ! 50 1262 Caullophyllum Blue Cohosh Root I 50 1263 j*Cheledonium majus Garden Celandine Herb 40 1264 Chiococca racemosa j Cachinca Root bark. . . 40 1265 Chrysophyllum ' Monesia j Bark j 40 1266 "Collinsonia Stone Root, Heal All. ... ! Root j 40 1267 Corallorhiza ; Coral Root, Crawley Root 50 1268 "Corydalis (Dicentra Can.). Turkey Corn Tuber 50 1269 Corypha cerefera Carnauba, Wax Palm . . . Root 50 1270 Cuminum Cyminum Cummin Seed Fruit 50 1271 *Draconitum Skunk Cabbage Root 50 1272 Duboisia Myoporoides. . . . Duboisia Leaves 30 1273 Equisticum Horsetail i Stems 40 1274 *Eryngium aquaticum Water Eryngo 1 Root 50 EXTRACTA FLUIDA — FLUID EXTRACTS. 469 UNOFFICIAL FLUID EXTRACTS CLASS C — Continued. LATIN NAME. COMMON NAME. 127; 1276 1277 1278 1279 I28o I2Sl 1282 1283 1284 1285 1286 1287 1288 12S9 1290 1291 1292 1293 1294 1295 1296 1297 1298 1299 I30O I301 1302 1303 1304 I305 1306 1307 1308 1309 I3IO 13" 1312 1313 1314 1315 1316 1317 1318 1319 1 J20 1321 1322 1323 1324 1325 1326 1327 1328 Eryngium yuccjefolium. . . *Euonymus Fceniculum Francisca uniflora Garrya Fremontii Hedeoma Helianthus Helleborus niger Hyoscyami radix Illicium Anisatum Inula Helenium Laurus nobilis Ledum palustre Manzanita(Arctostaphylos) Matricaria Monarda ristulosa M onarda punctata Monotropa uniflora Myrtus Checan Nuphar advena Nymph;va odorata Onosmodium Virginianum Origanum Paonia officinalis *Penthorium sedoides * Phytolacca Phellandrium aquaticum. . Piscidia Polemonium reptans Polygonatum giganteum. . Potentilla Canadensis. .. . Potentilla Tormentilla. . . . Populus alba Ptelea trifoliata Pulsatilla (Anemone P.) . . Pycnanthemum Quillaia * Rhus aromatica Rhododendron maximum. Robina Sabal serrulata I Salix alba Salix nigra Saponaria Satureja hortensis Sessamum orientate Simaba Cedron Sterculia acuminata. .... Sy mplocarpus ( 1 Iraconitum) Veratrum album Xanthium Strumarium. . . . Xanthium spinosum U vularia perfoliata Viburnum opulus Zanthorrhiza Apiifolia 1 Corn Snakeroot Wahoo Fennel Seed Manaca Quinine Bush Pennyroyal Sunflower Black Hellebore Henbane Star Anise Seed Elecampane Bay Laurel, Bay Tree. Labrador Tea Glauca German Chamomile. . . Wild Bergamont Horsemint Fit Root, Ice Plant Cheken, Chequin Yellow Pond Lily White Pond Lily False Gromwell Wild Majoram Peony Virginia Stone Crop. . . Garget or Poke Water Fennel Jamaica Dogwood Abscess Root Soloman's Seal Cinquefoil, Firefinger. Tormentil White Poplar Waferash, Hoptree. . . Pulsatilla Mountain Mint Soap Tree Sweet Sumach Great Laurel Locust Tree Palmetto Saw Perries. . White Willow Black Willow Soapwort Summer Savory Penne Cedron Seed Cola or Kola Skunk Cabbage White Hellebore Cockleburr Spiney Hurweed Bellwort 1 ramp, Cranberry.. . . Yellow' Root Root . Bark. . Fruit . Root . 50 50 50 50 Herb I 40 Leaves Seed. Root Root Fruit Root Leaves Twigs, Tops Leaves Flowers Herb Plerb Plant Leaves Root Root Seeds, root. . Herb Root Herb 30 Root Seed Root bark. . . Root Root Plant Root Inner bark. . Inner bark. . Herb Herb Bark Root Bark . , Inner bark. . Leaves 40 Fruit .. Bark . . Park . . Root . . Herb.. Leaves Seed . . Nuts.. Root . . Root . . Burrs . . Plant . . Root . . Hark. . Root . . 470 EXTRACTA FLUIDA — FLUID EXTRACTS. Fluid Extracts Class D. The following drugs require Diluted Alcohol as a menstruum for preparing their fluid extracts; equal measure of Alcohol and water, although it is not the present officinal standard for Diluted Alcohol, will be of sufficient Alcoholic strength for these Fluid Extracts. To complete the formula for any Fluid Extract in this class, put the name of the drug and the fineness of powder required in the following 1330. General Formula. The Drug in No. powder, . . . 16^ ounces av. Diluted Alcohol, a sufficient quantity. Moisten the drug with from 8 to 10 ounces of Diluted Alcohol mixed with the Glycerin, if any is directed to be used, and macerate for 24 hours in a covered vessel in a warm place ; transfer to the water-bath percolator, pack firmly, pour upon it sufficient Diluted Alcohol to saturate and cover the drug, and set in a warm place for two days, then heat moderately and after one hour begin to percolate slowly, adding Diluted Alcohol to the drug and continuing the heat and percolation until 13 ounces have passed, which reserve. Turn off the heat and continue the percolation with Diluted Alcohol until the drug is exhausted. Distill the Alcohol (}4 the measure) from this last portion, evaporate the residue to a soft extract, which dissolve in the reserved portion and add enough Diluted Alcohol to make a pint of the Fluid Extract. The Alcohol remaining in the drug after percolation may be recovered by distillation. The* indicates that Fluid Extracts are also prepared from the fresh or green drug. See Green Plant Fluid Extract. U. S. Official Fluid Extracts. The following are the U. S. Official Fluid Extracts made with diluted AlcoJwl, in accordance with this formula. When EXTRACTA FLUIDA — FLUID EXTRACTS. 471 Glycerin is used it should be added to the diluted Alcohol used to moisten the drug : 1331. Extractum Arnica; Radicis Fluidum — Fluid Extract of Arnica Root. — Arnica Root in No. 50 powder — Diluted Alcohol. Make a fluid extract as directed (1330). 1332. Extractum Calumbae Fluidum — Fluid Extract of Calumba {Columbo). — Calumba (Columbo), in Xo. 20 powder — Diluted Alcohol. Make a fluid extract as directed (1330). 1333. Extractum Chimaphilae Fluidum — Fluid Extract of Chima- pliila (Pifisissewa). — Chimaphila (Prince's Pine), in No. 20 powder — Diluted Alcohol — Glycerin ( 1% fl.ounce to a pint.) Make a fluid extract as directed (1330J. 1334. Extractum Chiratse Fluidum — Fluid Extract of Chiraia. — Chirata in No. 30 powder — Diluted Alcohol — Glycerin (\% fl.ounce to a pint). Make a fluid extract as directed (1330). I 335- Extractum Conii Fluidum — Fluid Extract of Conium (Cicuta Water Hemlock). — Conium (Fruit), in No. 40 powder — Diluted Alcohol — Diluted Hydrochloric Acid ( l / 2 fl.ounce to a pint). Make as directed (1330), adding the diluted acid to the portion to be evaporated. 1336. Extractum Cornus Fluidum — Fluid Extract of Cornus {Dog- wood). — Cornus (Dogwood Bark), in No. 50 powder — Diluted Alcohol — Glycerin (2 l / 2 fl.ounces to a pint). Make a fluid extract as directed (1330). 1337. Extractum Dulcamarae Fluidum — Fluid Extract of Dulcamara {Bittersweet). — Dulcamara (Bittersweet), in No. 50 powder — Diluted Alcohol. Make a fluid extract as directed ( 1330. 1338. Extractum Erythroxyli Fluidum — Fluid Extract of Erythroxy- lou (Coca). — Erythroxylon (Coca leaves), in No. 40 powder — Diluted Alcohol. Make a fluid extract as directed ( 1330). The Br. Liquid Extract 1 is similar to this fluid extract. 1339. Extractum Eupatorii Fluidum — Fluid Extract of Eupatorium • [Thoroughworf). — Eupatorium (Boneset), in No. 30 powder — Diluted Alcohol. Make a fluid extract as directed (1330). 1340. Extractum Gentianae Fluidum — Fluid Extract of Gentian — Gentian in Xo. 20 powder— Diluted Alcohol. Make a fluid extract as directed f 1330). 1341. Extractum Geranii Fluidum — Fluid Extract of Geranium {Cranesbill). -Geranium (Cranesbill Root), in No. 30 powder — Diluted Alcohol —Glycerin ( 1 ' 4 fl.ounce in a pint). Make a fluid extract as directed <'33°J- 1342. Extractum Glycyrrhizse Fluidum —Fluid Extract of Glycyrrhiza {Liquorice). Glycyrrhiza (Liquorice Root), in No. 30 powder — Diluted 472 EXTRACTA FI.UIDA — FLUID EXTRACTS. Alcohol — Water of Ammonia (ij4 fl. ounce in a pint). Mix the Water of Ammonia with the first portions diluted Alcohol used and make a fluid extract as directed (1330). 1343. Extractum Krameriae Fluidum — Fluid Extract of Krameria (Rhatany). — Krameria (Rhatany), in No. 30 powder — Diluted Alcohol — Glycerin (2}{ fl. ounces in a pint). Make a fluid extract as directed (1330). 1344. *Extractum Leptandrae Fluidum — Fluid Extract of Leptandra {Culver's Root). — Leptandra (Black Root) in No. 50 powder — ■ Diluted Alco- hol — Glycerin (2 fl. ounces in a pint). Make a fluid extract as directed (1330). 1345. * Extractum Lobeliae Fluidum — Fluid Extract of Lobelia. — Lobelia (herb) in No. 50 powder. — Diluted Alcohol. Make a fluid extract as directed (1330). 1346. Extractum Pareirae Fluidum — Fluid Extract of Pareira. — Pareira in No. 40 powder — Diluted Alcohol — Glycerin {2% fl.ounces in a pint.) Make a fluid extract as directed (1330). 1347. Extractum Pilocarpi Fluidum — Fluid Extract of Pilocarpus (faborandi). Pilocarpus (Jaborandi) in No. 30 powder — Diluted Alcohol. Make a fluid extract as directed ( 1330). 1348. Extractum Quassias Fluidum — Fluid Extract of Quassia. — Quassia in No. 50 powder — Diluted Alcohol. Make a fluid extract as directed (1330). 1349. Extractum Rhois Glabrae Fluidum — Fluid Extract of Rhus Glabra (Sumac). — Rhus Glabra (Sumac " bobs ") in No. 30 powder — Dilu- ted Alcohol — Glycerin (i# fl.ounces in a pint). Make a fluid extract as directed (1330). 1350. Extractum Rosae Fluidum — Fluid Extract of Rose. — Red Rose in No. 30 powder — Diluted Alcohol — Glycerin (1% flounce in a pint). Make a fluid extract as directed (1330). 1351. Extractum Rumicis Fluidum — Fluid Extract of Runiex (Yel- low Dock). — Rumex (Yellow Dock) in No. 30 powder — Diluted Alcohol. Make a fluid extract as directed (1330). 1352. Extractum Spigeliae Fluidum — Fluid Extract of Spigelia (Pink Root). — Spigelia (Pink Root) in No. 50 powder — Diluted Alcohol. Make a fluid extract as directed (1330). I 353- * Extractum Stillingiae Fluidum — Fluid Extract of Stillingia ( Queensroot). — Stillingia in No. 30 powder — Diluted Alcohol. Make a fluid extract as directed (1330). 1354. Extractum Uvae Ursi Fluidum — Fluid Extract of Uva Ursi. — Uva Ursi in No. 30 powder — Diluted Alcohol — Glycerin (\)i fl.ounce in a pint). Make a fluid extract as directed (1330). EXTRACTA FLUIDA — FLUID EXTRACTS. 473 Unofficial Fluid Extracts. The following are unofficial fluid extracts which require Diluted Alcohol as a menstruum for preparing them, and are made in the same manner as directed (1330). Many of these extracts may be made with a menstruum of less alcoholic strength, but, generally, their soluble properties are better held in solution with Diluted Alcohol than with a weaker menstruum. UNOFFICIAL FLUID EXTRACTS CLASS D. 1355 1356 1357 1358 1359 1360 1361 1362 1363 1364 I3 r >5 1366 1367 1368 1369 1370 1371 1372 1373 1374 1375 1376 1377 1378 1379 1380 1381 1382 1383 1384 1385 1386 1387 13S8 1389 1390 1 39 1 1392 1393 1394 1395 LATIN" NAME. Abies balsamea Absinthium (Artemisia). . Acanthus mollis Achillea millefolium Adiantum Agrimonia Eupatoria . . . . *Aletris farinosa Althaea flores Ambrosia trifida Ampelopsis *Amygdalus Persica ...... Anagallis arvensis Anemone Anthemis nobilis Andira inermis Aralia hispada Aralia spinosa Aralia nudicauhs Aralia racomosa Areca catechu Aster punicus Asparagus officinalis Aurantii cortex, dulcis. . . . Betula Lenta Bidens bipinnata Bistorta ( Pologonum B.). Borago officinalis Caffea CafTea tosta Carduus Benedictus Carya alba I arthamus tinctorius Cascara amarga Cascara sagrada < lataria ( Nepeta C.) Cephalanthus Celastrus scandens < en is Canadensis Cetraria Ceonothus Americanus. . . Chelone glabra COMMON NAME. Balsam Fir Tree Wormwood Acanthus Yarrow Maidenhair Fern Agrimony Unicorn, Star Grass. . Marshmallow Rich weed, Ragweed.. Virginia Creeper Peach Tree Scarlet Pimpernel. . . . Wood Anemone English Chamomile. . Cabbage Tree, Yellow Dwarf Elder Southern Prickly Ash. Amer. Sarsaparilla. . . Spikenard Betel nut Red Stalked Aster. . . Asparagus Sweet Orange Peel.. . Black or Cherry Birch Spanish Needles Pistort, Snakeweed.. . Porage < offee Berries, green . Coffee Perries, roasted Blessed Thistle White Hickory Safflower, Am. Saffron I londuras Park Rhamnus Prushiana. . . Catnip, Catmint Button Push Staff Tree Judas Tree Iceland Moss Jersey Tea, Red Root. Balmony, Snakehead.. 1 Powder I No. Inner bark. . 40 Leaves, tops. 30 Leaves | 30 Leaves, tops. 30 Plant 30 Whole plant. 30 Root 50 Flowers 20 Herb 30 Twigs, bark. 30 Leaves 30 Herb 30 Flerb 30 Flowers 30 Park 40 Root 40 Bark 40 Root 30 Root 30 Seed 50 Root 40 Young shoots 30 Fruit rind. . . 20 Bark 40 Root 50 Rhizome .... 50 Herb 30 Seeds ! 30 Seeds 40 Leaves, tops. 30 Inner bark. . 50 Flowers 30 Bark 40 Park 50 Herb 30 Park 50 Root bark. . . 50 Root bark.. . 50 Entire plant. 20 Root 50 1 1 t-rli 20 474 EXTRACTA FLUIDA — FLUID EXTRACTS. UNOFFICIAL FLUID EXTRACTS CLASS D — Continued. LATIN NAME. I39 6 1397 I39S 1399 1400 140 1 1402 M03 1404 I405 1406 1407 1408 1409 1410 1411 1412 1413 1414 1415 1416 1417 141S 1419 1420 1421 1422 1423 1424 1425 1426 1427 1428 1429 1430 1431 1432 1433 1434 1435 1436 1437 1433 M39 1440 1441 1442 1443 1444 1445 1446 1447 144S 1449 I450 Chicorium Intybus China ( Smilax glabra).. *Chionanthus Virginica. . Cochleria, fresh Colocynthus Comptonia asplenifolia. . Conii folia Convulvulus panduratus. Coptis teeta Coptis tnfolia Cornus circinata Cornus sericea Crocus sativus Cucumis citrullus Cucumis pepo Cunderango Cunila Mariana Cynoglossum Cyperus articulatus Diospyros cortex , Diospyros fructus Dirca palustris , Dulcamara (Solanum D.), Elephantopus tomentosus Epiphegus ( Orobanche). . Epigiva repens *Epilobium Erythracea Erythnea Centaurium. . . Eupatorium aromaticum. Eupatorium perfoliatum. Eupatorium purpureum . Euphrasia Fagus ferruginea *Frankenia Frasera Fraxinus Americana .... Fraxinus sambucifolia. . . Fucus vesiculosus Fumaria officinalis Galla Galium aperine Galium verum Gaultheria Gentiana quinqueflora. . . Geum rivale Geum urbanum Gnaphalium Gouania Domingensis. . . Granati fructus cortex. . . Granatum Gratiola officinalis Cuaco ( Mikania G.) Humatoxylon Hamamelidis cortex COMMON NAME. Chicory China Root Fringe Tree Scurvy Grass Colocynth, Bitter Apple. Sweet Fern Cicuta, Conium Wild Jalap J East Indian Coptis ! Coptis, Gold Thread I Green Ozier Swamp Dogwood j True Saffron Watermelon Seed Pumpkin Seed ; Conderango Dittany, American Hound's Tongue Adrue Persimmon Persimmon Leatherwood 1 Bittersweet Elephant's Foot Cancer Root Trailing Arbutus Wickup or Willow Canchalagua European Centaury White Snakeroot Boneset, Thoroughwort. Queen of the Meadow. . Eyebright American Beech Verba Rheuma American Columbo White Ash Black Ash Bladder or Sea Wrack. . Fumitory Nutgall i Cleavers j Lady's Bedstraw Wintergreen Five-Flowered Gentian. Water Avens 1 European Avens Life Everlasting Chewstick Pomegranate Pomegranate Hedge Hyssop Guaco Logwood Witch Hazel Root Rhizome Root bark. . . Bruised herb. Fruit Herb Leaves Root Rhizome.. . . Entire plant. Bark Bark Stigmas Seed Seed Bark Root Herb Root Bark Green fruit. . Bark Twigs Herb Plant Leaves Herb Herb Herb Root Herb Root Herb Inner bark. . Plant Root Bark Bark Plant Leaves Excrecenses. Herb Herb Leaves Plant Root Root Herb Stems Fruit rind . . . Root bark . . . Herb Leaves Wood Bark Powder No. EXTRACTA FLUIDA — FLUID EXTRACTS. 475 UNOFFICIAL FLUID EXTRACTS CLASS D — Continued. LATIN* NAME. COMMON NAME. Powde No. 1451 He'.ianthemum Frostwort, Rockrose. . . . Herb 30 1452 Hemidesmus Indian Sarsaparilla. . . . Root 40 1453 Hepatica Liverwort, Kidney Leaf. Leaves 30 1454 Heracleum Masterwort Leaves, root. 30 1455 Heuchera Alum Root Root 40 1456 Hippocastanum Horse Chestnut Bark 40 1457 Hydrangea arborecens. . . Hydrangea, Seven B'ks. Root 50 1458 Hyssopus Hysop (Am., European) Plant 30 1459 Hypercum perforatum. . . Johnswort Herb 30 1460 Ilex Paraguayensis Paraguay Tea , Leaves 30 1461 Jeffersonia diphylla Twin Leaf Root 40 1462 Jacaranda Caroba Caroba Leaves 40 1463 Juglans nigra Black Walnut Bark 40 1464 Juglans regia European Butternut. . . . Leaves 30 1465 Kalmia latifolia Mountain Laurel Leaves 30 1466 Lactuca virosa Wild Lettuce Leaves 30 1467 Lappae fructus Burdock Seed Fruit 40 1468 Lappa; radix Burdock Root Root 40 1469 , Larix Americana Tamarack Bark 40 1470 Lavendula vera ' Lavender Flowers 30 1471 Leonorus cardiaca Motherwort Herb 30 1472 Limonis cortex Lemon Peel Fruit rind... 20 1473 Liatris odoratissima Vanilla Plant Leaves 30 1474 Liatris spicata Button Snakeroot Root 50 1475 Liatris squarrosi Blazing Star Root 50 1476 *Lycopus Europaeus Bitter Bugle Herb 30 1477 Lycopus Virginicus Bugle Weed Herb 30 1478 Maltum Barley Malt Malted Seed . 30 1479 Malva sylvestris Common Mallow Leaves 20 1480 Mangifera Indica Mango Bark rind ... 30 148 1 Mangostana Mangosteen Fruit rind. . . 30 1482 Marjorana (Origanum M.) Sweet Marjoram Herb 30 1483 Marrubium vulgare Hoarhound Herb 30 1484 Maruntacotula May Weed Herb 30 1485 Melissa Sweet Balm Herb ! 30 i486 Melilotus officinalis Melilot, Sweet Clover. . . Ilowers 30 1487 Mentha piperita Peppermint Herb 30 1488 Mentha viridis Spearmint Herb 30 Menyanthes trifoliata. . . . Buck Bean, Bog Bean. . Leaves 30 [490 Mikania Guaco duaco Leaves Leaves 30 1491 Mitchella repens Partridgeberry Herb 30 140,2 Moras ni^ra Mulberry Root 40 1 4')3 Myriea Gale Sweet < iale Herb 30 i|M ' 1 in iihera biennis livening Primrose Twigs, leaves 40 [495 Osmarrhiza longistyl is . . . Sweet Cicely Root 40 [496 Osmunda regalis Buckhorn Brake Root 40 [ \')~ < >strya Virginica Ironwood Bark 40 1 it Oxydendron arboreum . . . Sourwood Twigs ' 30 Panax (Aralia quiquefolia) Ginseng Root 30 1500 Papaver Sonimiferam. . . . Poppy Cap., leaves. 50 1501 Pepo ( Cucurbita P.) Pumpkin Seed 20 1502 Persia gratissima Alligator Pear Seed 40 Petroselinum Parsley Root, seed., 30 i--"i Pinus Strobus White Pine Inner bark. , |0 1505 I Phoradendron American Mistletoe ... 1'lant 30 476 EXTRACTA FLUIDA — FLUID EXTRACTS. UNOFFICIAL FLUID EXTRACTS CLASS D — Continued. 1506 1507 1508 1509 1511 1512 1513 i5M 1515 1516 1517 151S 1519 1520 1521 1522 1523 1524 1525 1526 1527 1528 1529 1530 i53i 1532 1533 1534 1535 1536 1537 1538 1539 1540 1541 1542 1543 1544 1545 1546 1547 1548 1549 1550 i55i 1552 1553 1554 1555 1556 1557 1558 1559 1560 1561 LATIN NAME. Plantago major Pinus Canadensis Polygala amara Polypodium vulgare Polytrichum Prinos verticillatus Pulmonaria Pyrethrum Parthenum.. Pyrola rotundifolia Pyrus Malus Quercus alba Rhamnus catharticus. . . . Rhamnus Prushiana Rhceas ( Papaver R.). . . . Ricini folia Rubus strigosus Rubia Rudbeckia Ruta graveolens Sabbatia angularis Sabbatia Elliottii Salvia officinalis Sambucus Canadensis. . . Sarracenia purpurea I Scrofularia nodosa *Senecio gracilis Simaruba officinalis Smilax Sarsaparilla Solidago odora Spirita tomentosa Statice Caroliniana Stigmata Maydis Symphytum officinale. . . Tabacum ( Nicotiana T.) . Tanacetum vulgare Tecoma radicans Thea Chinensis Theobroma Cacao Thymus Vulgaris Trifolium partense Triosteum perfoliatum. . Tilia Tonga Tormentilla Tussilago Farfara ' Ulmus fulva Umbellaria Urtica dioica. ... Ustilago Maydis VerbascUm thapsus Verbena hastata Viburnum dentatum.. . . , Viola tricolor Viscum Album Vaccinum Crassifolium. . COMMON NAME. Powder No. Common Plantain Hemlock Bitter Polygala Polypody Hair Cap Moss Black Alder Lungwort Feverfew Canker Lettuce Apple Tree White Oak Buckthorn Cascara Sag. Chittem. . . Red Poppy Castor Oil Leaves Red Raspberry Madder Thimbleweed Rue Am. or Red Centaury . . Quinine Flower Sage Elder Pitcher Plant Carpenter's Square Life Root Simaruba Bamboo Brier Golden Rod Hardhack Marsh Rosemary Corn Silk Comfrey Tobacco Tansy Trumpet Creeper Tea Chocolate Thyme Red Clover Fever Wort Linden Mixed Fiji Island Barks Tormentil Coltsfoot Slippery Elm California Laurel Nettle Corn Smut or Ergot. . . . Mullein Vervain Arrow Wood Wild Violet or Pansy. . . Mistletoe Creeping Huckleberry. . Plant 30 Inner bark. . 30 Plant 30 Root 40 Plant 30 Bark 40 Herb 30 Herb 30 Herb 30 Root bark. . . 40 Bark ! 40 Berries 20 Bark 40 Flowers 30 Leaves 30 Leaves 30 Root 30 Tops 30 Leaves 30 Plant 30 Herb 30 Leaves 30 Bark, flowers 30 Plant 30 Root 30 Plant 30 Bark 30 Root 30 Herb 30 Herb 30 Root 40 Stigmas 20 Root 30 Leaf 30 Herb 30 Bark 40 Leaves 30 Seeds 40 Herb 30 Flowers 30 Herb 30 Flowers 30 Barks 50 Rhizome. ... 30 Leaves 40 Bark 30 Leaves ' 30 Root ! 40 Fungus j 50 Flowers, l'v's 30 Herb j 30 Bark 40 Plant j 30 Plant 30 Plant I 30 EXTRACTA FLUIDA — FLUID EXTRACTS. 477 Other U. S. Official Fluid Extracts. The following U. S. Official Fluid Extracts cannot well be included under the foregoing classes as they require a differ- ent menstruum or some special manipulation. The essential details only are given here. For full detailed formulas, see Fenner's Working Formulae. They should be made by water-bath percolation in a manner similar to those classed in A, B, C, or D. 1562. Extractum Castaneas Fluidum — Fluid Extract of Castanea [Chestnut Leaves). — Castanea (Chestnut Leaves) in No. 12 powder i6 2 i ounces av., Water, Alcohol, each sufficient. Percolate the drug with hot Water till exhausted, evaporate the percolate, by water-bath, to 2 pints, add 5 fl. ounces Alcohol, let stand 24 hours for precipitate to subside, filter through calico, evaporate the filtered liquid to 1272 fl. ounces, and add enough Alcohol to make a pint. 1563. Extractum Cinchonae Fluidum — Fluid Extract Cinchona (Calis- aya). — Yellow Cinchona (Galisaya Bark) in No. 50 powder 1673 ounces av., Glycerin 5 fl. ounces, Alcohol, Water, each sufficient. Mix the Glycerin with 14.% fl.ounces of Alcohol and percolate first with the mixture, then with a menstruum of 3 measures of Alcohol mixed with one measure of Water until the drug is exhausted. Reserve the first 13 fl.ounces. Distill the Alcohol from the remainder of the percolate and evaporate the residue to 3 fl.ounces, which add to the reserved portion. Liquid Extract of Cinchona — The Br. P. directs an Aqueous Fluid Extract of Cinchona to be prepared from Cinchona Bark by the aid of a small quantity of Hydrochloric Acid. This is then to be assayed and the quantity of liquid so regulated that it shall contain 5 per cent, of total Alkaloids. 1564. Extractum Ergotae Fluidum — Fluid Extract of Ergot [Spurred or Smut Rye). Ergot recently ground in No. 50 powder 1673 ounces av., Alcohol, Water, each sufficient, diluted Hydrochloric Acid 1 fl.ounce. Per- colate first with 6 fl.ounces Alcohol mixed with 10 fl.ounces of Water, then with Water. Reserve first 13 ounces that pass. Mix the dilute Hydrochloric Acid with the remainder of the percolate, evaporate to 3 ounces, and add to the reserved portion. The Br. Liquid Extract if Ergot is similar to this but contains no acid. 1565. Extractum Frangulae Fluidum — Fluid Extract of Frangula {Buckthorn Bark). Frangula (Buckthorn Bark) in No. 40 powder \<>' , ounces av , Alcohol, Water, each sufficient. Percolate firsl with 6 fl.ounces Alohol mixed with 8 fl.ounces Water, then with Water until exhausted. 478 EXTRACTA FLUIDA — FLUID EXTRACTS. Reserve the first 13 fl .ounces of percolate, evaporate the remainder to 3 ft ounces, and add. The Br. Liquid Extract of Rhavinus Frangula is similar to this Fluid Extract. 1566. Extractum Hamamelidis Fluidum — Fluid Extract of Hamame- lis {Witch //a:.c/).— Hamamelis (Witch Hazel Leaves) in Xo. 40 powder i6 2 ; ounces av., Alcohol, Water. Percolate first with 6 fl.ounces Alcohol mixed with 12 11. ounces of Water, then with Water until exhausted. Reserve the first 13 fl.ounces of percolate, evaporate the remainder to 3 fl.ounces, and add. 1567. Extractum Ipecacuanha Fluidum — Fluid Extract of Ipecac. — Ipecac in No. 60 powder 16-3 ounces av., Alcohol, Water, each sufficient. Percolate the drug with Alcohol until exhausted, distill off the Alcohol until only 4 rl. ounces remain, mix this with a pint of Water and evaporate by water-bath to 12 rl. ounces, let stand 48 hours, then filter and add Water through the filter until the washings are tasteless, evaporate the filtrate and washings to half a pint, and, when cool, add half a pint of Alcohol, and filter. This process removes all the resinous matter and makes an extract mixable with syrup without cloudiness. 1568. Extractum Lactucarii Fluidum — Fluid Extract of Lactuca- rium. — Lactucarium 167-3 ounces av. is first macerated and washed with gasoline, then dried and percolated with a menstruum of Alcohol 8 fl.ounces mixed with Water 20 fl.ounces. The first 12 fl.ounces of percolate are reserved and the remainder evaporated to 4 fl.ounces and added. This makes an extract that can be mixed with syrup to make Syrup of Lactucarium. 1569. Extractum Pruni Virginianae Fluidum — F/uid Extract of Wild Cherry. — Wild Cherry in No. 20 powder 167^ ounces av., glycerin 1% fl.ounces, diluted Alcohol, Water, each sufficient. Mix the Glycerin with 6 ounces of Water and moisten the drug, macerate 48 hours, pack in percola- tor and percolate with diluted Alcohol until 13 fl.ounces have passed, which reserve, then with Water until exhausted. Evaporate the last portion to 3 fl.ounces and add to the reserved portion. 1570. Extractum Sarsaparilla Fluidum — /'///'/,'/ Extract of Sarsapa- rilla. — Sarsaparilla in No. 30 powder 167^ ounces av., Glycerin 1% fl. ounce, Alcohol, Water, each sufficient. Mix the Glycerin with 6 fl.ounces Alcohol and 10 fl.ounces of Water and percolate first with this mixture, then with a mixture of 1 measure of Alcohol to 2 measures of Water until the drug is exhausted. Reserve the first 13 fl.ounces and evaporate the remainder to 3 fl.ounces, and add to the reserved portion. The Br. Liquid Extract of Sarsaparilla is similar to this but contains a little sugar. 1 57 1. -Extractum Scutellariae Fluidum — Fluid Extract of Scutellaria [Skullcap). — Scutellaria (Skullcap) in No. 30 powder \6% ounces av., Alco- hol, Water, each sufficient. Mix Alcohol and Water in the proportion of 10 EXTRACTA FLUIDA — FLUID EXTRACTS. 479 fl. ounces of Alcohol to 16 fl. ounces of Water and percolate the drug with the mixture until exhausted, reserve the first 13 fl. ounces of percolate, distill the Alcohol from the remainder, and evaporate the residue to 3 fl. ounces and add to the reserved portion. 1572. Extractum Sennae Fluidum — Fluid Extract of Senna. — Senna in Xo. 20 powder 1673 ounces av., Alcohol, Water, each sufficient. Mix Alcohol and Water in the proportion of 13 fl. ounces Alcohol to 16 fl. ounces of Water, and percolate, reserving the first 13 fl. ounces, distilling the Alcohol from the remainder and evaporating the residue to 3 fl. ounces, which add to the reserved portion. 1573. Extractum Taraxaci Fluidum — Fluid Extract of Taraxacum (Dandelion). — Taraxacum (Dandelion Root) in No. 20 powder 16%' ounces av., Alcohol, Water, each sufficient. Mix Alcohol and Water in the propor- tion of 9 fl. ounces of Alcohol to 12 fl. ounces of Water and percolate with the mixture, reserving the first 14 fl. ounces of percolate and distilling the Alcohol from the remainder, evaporating the residue to 2 fl ounces, which add to the reserved portion. The Br. Liquid Extract of Dandelion is similar to this Fluid Extract. Other Unofficial Fluid Extracts Requiring Special Treatment. The following arc unofficial Fluid Extracts requiring special treatment, which cannot well be included in Classes A, B, C and 1 ) : 1574. Fluid Extract of Cinchona, Detannated — Mix 6 ounces of freshly precipitated, washed, moist Hydrated Peroxide of Iron (Ferric Hydrate) with a pint of Fluid Extract of Cinchona, and allow to stand for 4 days, shaking frequently; then filter, adding through the filter enough Dilu- ted Alcohol to make the measure a pint. If the filtered extract still shows traces of Tannin when tested with Tincture of Chloride of Iron, add an ounce more of the moist Ferric Hydrate, and proceed as before, until it is detannated. 1575. Fluid Extract Garlic — Allium Sativum. — Garlic, crushed, 1' 1 ounces av., Alcohol 10 fl.ounces, Water, a sufficient quantity. Mash the Garlic t" a pumice in a mortar, pour the .Alcohol upon it and macerate for twenty-four hours in a covered vessel in a warm place; transfer to the water- hath percolator, pack moderately, pour upon it sufficient Water to cover the drug, heat very moderately at once, and after one hour begin to percolate, adding Water to the drug and continuing the heat and percolation until a pint of the fluid extract has passed. Although this fluid extract does not 480 EXTRACTA FLUIDA — FLUID EXTRACTS. properly come in this class, it is placed here for want of a more convenient place. 1576. Fluid Extract of Hydrastis, Purified — Fluid Hydrastis. — Hy- drastis in No. 50 powder 1673 ounces aw, Glycerin 5 fl. ounces, Alcohol, Water, each a sufficient quantity. Moisten the powder with 8 ounces of Alcohol, and pack firmly in the water-bath percolator, pour upon it a pint of Alcohol and set in a warm place for two days ; then heat very moderately and after one hour begin to percolate, adding Alcohol to the drug and con- tinuing the heat and percolation until it is exhausted. Distill the Alcohol from the percolate until it is reduced to a soft extract. To this add the Glycerin and 6 ounces of Water, and agitate ; then filter and add through the filter enough Water to make a pint of the fluid extract. The resinous matter remains on the filter. This makes a preparation similar to " Fluid Hydrastis," containing the valuable principles of the drug which are soluble in an aqueous menstruum, and omitting the objectionable ones that are obtained when Water or Alcohol alone is used as a menstruum. 1577. Fluid Extract Ignatia Bean. — Ignatia Bean in No. 60 powder 1654 ounces av., Alcohol, Water, each a sufficient quantity. This Fluid Ex- tract is made with the same menstruum and in precisely the same manner as Fluid Extract of Nux Vomica, which see. 1578. Fluid Extract of Senna, Alcoholized — Purified Fluid Extract of Senna. — Senna in No. 20 powder 16% ounces av., Alcohol, Water, each a sufficient quantity. Pack the Senna moderately in the water-bath percolator, pour upon it enough Alcohol to saturate and cover it and set in a warm place for twenty-four hours ; then heat very moderately and after one hour begin to percolate, adding a pint and a half of Alcohol to the drug and continuing the per- colation until it will no longer drop. [The object of this proceeding is to remove from the Senna the principles which cause it to " gripe " when taken. The Alcohol which is used may be distilled.] Then pour Water upon the Senna and percolate until exhausted. Reserve the first 12 fl. ounces that pass, evap- porate the remainder to 4 fl. ounces and add to the reserved portion to make a pint of the Purified Fluid Extract. 1579. Fluid Extract Vanilla— [One half strength.] — Vanilla 8 ounces av., Alcohol, Water, each a sufficient quantity. Mix three measures of Alco- hol with two measures of Water, and having cut the Vanilla in fine pieces and reduced it to a coarse powder by thoroughly beating in a mortar, moisten it with 6 ounces of the menstruum, pack firmly in ihe water-bath percolator, pour upon it 10 ounces of menstruum and set in a warm place for seven days ; then heat moderately and after one hour begin to percolate slowly, adding menstruum to the drug and continuing the heat and percolation until \\Yz fl.ounces have passed, which reserve. Continue the percolation with the menstruum until the drug is exhaused, then distill the Alcohol from this last portion, evaporate the residue to a soft extract, add to the reserved por- tion, and afterward sufficient menstruum to make a pint of the fluid extract. After standing a few days filter through muslin. EXTRACTA FLUIDA — FLUID EXTRACTS. 481 It will be observed that this is but half the strength of ordinary fluid extracts. It is thus made because a fluid extract of full strength cannot be obtained without impairing the flavor of the preparation by the heat required to evaporate it. To make Flavoring Extract of Vanilla from this Fluid Extract, use from i to 2 fl. ounces, with enough Alcohol and Water mixed in the proportion of three measures of Alcohol to two of Water to make a pint. To make Tincture of Vanilla, U. S., 1880, use 3 ounces of this fluid extract with enough Alcohol and Water, mixed as above, to make a pint. 1580. Fluid Extract Wild Cherry, Detannated. — Mix 6 ounces freshly precipitated, washed, moist, Hydrated Peroxide of Iron (Ferric Hydrate) with a pint of Fluid Extract of Wild Cherry and allow to stand for four days, shaking frequently ; then filter, adding through the filter enough Diluted Alcohol to make the measure a pint. If the filtered extract still shows traces of tannin, when tested with Tincture of Chloride of Iron, add an ounce more of the moist Ferric Hydrate and pro- ceed as before until it is detannated. Compound Fluid Extracts. Under this heading are included all fluid extracts that are made from two or more powdered drugs combined. As only two of them are official, they are called by their ordinary commercial or trade names as they are known and quoted in the market. Compound fluid extracts may be conveniently made by mixing the fluid extracts of the drugs which compose them in the same proportion as they are directed to be used in the formulas. The prescribing and use of compound fluid extracts should be discouraged, for the reason that there is no official standard for them, and as made by different manu- facturers they represent varying proportions of the drugs composing them, and are therefore indefinite. The following formulae contain the essential directions for making the fluid extracts, but detailed formulas are given in full in FENNER'S WORKING FORMUL E : 1581. Fluid Extract Blackberry Compound.— Blackberry Root 12 ' 2 ounces av., Cinnamon 2 ounces av., Nutmeg, Coriander, each 1 ounce av., all in No. 40 powder, Glycerin 2 flounces, Alcohol 2, Water 1. a sufficient quantity. Make a pint of fluid extract as directed (l22l). 482 EXTRACTA FLl'IDA — FLUID EXTRACTS. 1582. Fluid Extract Black Cohosh Compound.— Black Cohosh in No. 40 powder, 6 ounces aw, Wild Cherry in No. 20 powder 4 ounces aw, Liquorice Root in No. 30 powder 4 ounces aw, Ipecac, Senega, each, in No. 40 powder, 1 ounce aw, Alcohol 2, Water 1, a sufficient quantity. Make a pint of fluid extract as directed (1221 ). 1583. Fluid Extract Blue Cohosh Compound. — Blue Cohosh in No. 40 powder %% ounces aw, Cramp Bark in No. 30 powder 3 ounces aw, Unicorn Root in No. 40 powder 3 ounces aw, Celery Root in No. 40 powder, 2 ounces aw, Alcohol 2, Water 1, a sufficient quantity. Make a pint of fluid extract as directed ( 1221). 1584. Fluid Extract of Buchu and Juniper with Acetate of Potassium. ■ — Buchu Leaves in No. 40 powder 8 ounces aw, Juniper Berries in No. 40 powder 4 ounces aw, Acetate of Potassium 5 ounces aw, Alcohol 2, Water 1. a sufficient quantity. Make 13 ounces of fluid extract from the Buchu and Juniper and add the Acetate of Potassium. 1585. Fluid Extract Buchu and Pareira Brava. — Buchu Leaves in No. 40 powder, Pareira Brava in No. 50 powder, each 8 ounces aw, Alcohol 2, Water 1, a sufficient quantity. Make a pint of fluid extract as directed (1221). 1586. Fluid Extract Buchu Compound. — Buchu Leaves, Juniper Berries, Cubebs, Uva Ursi, each in No. 50 powder 4 ounces aw, Alcohol a sufficient quantity. Make a pint of fluid extract as directed (1069). 1587.— Fluid Extract of Cardamom Compound.— Cardamom, Cinna- mon, each 6 l / 2 ounces aw, Caraway 2 ounces aw, Cochineal i l /z ounce aw. all in No. 50 powder, Alcohol 3, Water i, a sufficient quantity. Make a pint of fluid extract as directed (1189). 1588. Fluid Extract Chinchona Aromatic. — Cinchona Bark S}4 ounces aw, Cinnamon 3 ounces aw, Nutmeg, Bitter Orange, each 2 ounces aw, all in No. 50 powder, Glycerin 2 fl. ounces, Alcohol 3, Water 1, a sufficient quantity. Make a pint of fluid extract as directed (1189). 1589. Fluid Extract Cinchona Compound. — Red Cinchona Bark in No. 50 powder 8}4 ounces aw, Bitter Orange Peel in No. 20 powder 6% ounces aw, Serpentaria in No. 50 powder 1% ounces aw, Glycerin 2 fl. ounces, Alcohol 3, Water 1, a sufficient quantity. Make a pint of fluid extract as directed (1 189). 1590. Fluid Extract Colocynth Compound.— Purified Aloes, Colocynth Pulp, each in coarse powder 6j4 ounces aw, Liquorice Root in coarse pow- der, Resin of Scammony, Cardamom Seed, each in fine powder 1 ounce aw, Carbonate of Potassium l / 2 ounce aw, Alcohol 3, Water 1, a sufficient quan- tity. Make a pint of fluid extract as directed (1189). 1591. Fluid Extract Dandelion and Rhubarb.— Dandelion, Rhubarb, each in No. 20 powder 8'^ ounces aw, Diluted Alcohol, a sufficient quantity. Make a pint of fluid extract as directed (1330). EXTRACTA FLUIDA — FLUID EXTRACTS. 483 1592. Fluid Extract Dandelion and Senna. — Dandelion, Senna, each in No. 20 powder 8y< ounces av., Diluted Alcohol a sufficient quantity. Make a pint of fluid extract as directed (1330). 1593. Fluid Extract Dandelion Compound. — Dandelion in No. 20 powder 14% ounces av., Mandrake in No. 40 powder, Conium Leaves in No. 30 powder, each 1 ounce av., Diluted Alcohol a sufficient quantity. Make a pint of fluid extract as directed (1330). 1594. — Fluid Extract Gentian Compound. — Gentian in No. 20 powder 10 ounces av.. Bitter Orange Peel in No. 20 powder 4 ounces av., Cardamom in No. 50 powder 2% ounces av., Alcohol 3, Water 1, a sufficient quantity. Make a pint of fluid extract as directed (1 189). I 595- Fluid Extract of Grindelia Compound. — Grindelia Robusta in No. 30 powder 8% ounces av., Jaborandi in No. 30 powder 4 ounces av., Cubeb in No. 40 powder, Conium Leaves in No. 30 powder, each 2 ounces av.. Alcohol, a sufficient quantity. Make a pint of fluid extract as directed (1069). 1596. Fluid Extract Helonias Compound. — Helonias in No. 40 powder 9 ounces av., Buchu, Gentian, Golden Seal, each in No. 30 powder 2)4 ounces av., Alcohol 2, Water 1, a sufficient quantity. Make a pint of fluid extract as directed (1221). I S97- Fluid Extract Hoarhound Compound. — Hoarhound in No. 20 powder, Red Root, Elecampane, Spikenard, Comfrey, Wild Cherry, Blood- root, each in No. 30 powder 234 ounces av., Alcohol 3, Water 2, a sufficient quantity. Make a pint of fluid extract as directed (1221). 1598. Fluid Extract Ipecac and Senega.— Ipecac, Senega, each in No. 50 powder 8> 3 ' ourices av., Diluted Alcohol, a sufficient quantity. Make a pint of fluid extract as directed (1330). 1599. Fluid Extract Jalap and Rhubarb.— Jalap in No. 40 powder, Rhubarb in No. 20 powder each 8)4 ounce av., Carbonate of Potassium )4 ounce av , Alcohol 3, Water 1, a sufficient quantity. Make a pint of fluid extract as directed 189J. 1600. Fluid Extract Jalap and Senna. Jalap in No. 40 powder, Senna in No. 30 powder, each 8*4 ounces av., Alcohol 2, Water 1, a sufficient quantity. Make a pint of fluid extract as directed ( 1221 >. 1601. Fluid Extract of Liquorice Compound — /vv Quinine Mixtures. Liquorice Knot 7 ounces av.. Wild Cherry 6 ounces av., Anise, Coriander, Caraway, each 1 ounce av.. all in No. 30 powder, Alcohol 3 tl.ounces, Water, Sufficient to make 13 tl.ounces of aqueous fluid extract, and add the Alcohol. 1602. Fluid Extract Lobelia Compound.— Lobelia Herb in No. 30 powder, Bloodroot, Skunk Cabbage in No. 40 powder, each $)4 ounces av., Alcohol 2, Water 1, a sufficient quantity. Make a pint of fluid extract as directed IIJ2II. 484 EXTRACTA FLUIDA — FLUID EXTRACTS. 1603. Fluid Extract of Mandrake Compound.— Mandrake in No. 50 powder, Leptandra in No. 40 powder, Senna in No. 30 powder, each 5 ounces av., Canella in No. 40 powder 1% ounce av., Alcohol 2, Water 1, a sufficient quantity. Make a pint of fluid extract as directed (1221). 1604. Fluid Extract of Matico Compound.— Matico, Buchu, Cubeb, each in No. 40 powder, $}4 ounces av., Alcohol a sufficient quantity. Make a pint of fluid extract as directed (1069). 1605. Fluid Extract Mitchella Compound.— Mitchella (Squaw Vine) 9>£ ounces av., Helonias Root, Blue Cohosh, each 1%. ounces av., Cramp Bark 2 ounces av., all in No. 40 powder, Alcohol 2, Water 1, a sufficient quantity. Make a pint of fluid extract as directed (1221). 1606. Fluid Extract Pink Root and Senna. — Pink Root in No. 40 powder 9^3 ounces av., Senna in No. 30 powder 5^ ounces av., Caraway, Anise, each in No. 50 powder 1 ounce av., Diluted Alcohol a sufficient quan- tity. Make a pint of fluid extract as directed (1330). 1607. Fluid Extract Poke Root Compound.— Poke Root (Phytolacca), Black Cohosh (Cimicifuga), each in No. 40 powder, 6% ounces av., Prickly- Ash Berries, Juniper Berries, each in No. 30 powder 2 ounces av., Alcohol, a sufficient quantity. Make a pint of fluid extract as directed (1069). 1608. Fluid Extract of Rhubarb and Senna.— Rhubarb in No. 20 pow- der 10 ounces av., Senna in No. 20 powder 3 ounces av., Coriander, Fennel and Liquorice, each in No. 50 powder, \% ounce av., Alcohol 2, Water 1, a sufficient quantity. Make a pint of fluid extract as directed (1221). 1609. Fluid Extract of Rhubarb, Aromatic. — Rhubarb in No. 20 pow- der 10^ ounces av., Cloves, Cinnamon, each in No. 50 powder 2 ounces av., Nutmeg in No. 50 powder 1 ounce av., Carbonate of Potassium x / 2 ounce av., Alcohol 3. Water 1, a sufficient quantity. Make a pint of fluid extract as directed (1069). 1610. Fluid Extract of Rumex Compound.— Compound Fluid Extract of Yellow Dock. — Yellow Dock Root in No. 20 powder 8}^ ounces av., False Bitter-Sweet Bark in No. 30 powder 4^ ounces av., American Ivy Bark, Figwort, each in No. 30 powder 2 ounces av., Diluted Alcohol a sufficient quantity. Make a pint of fluid extract as directed (1330). 161 1. Fluid Extract Sarsaparilla and Dandelion.— Sarsaparilla, Dan- delion, each in No. 30 powder, 8}<, ounces av., Diluted Alcohol a sufficient quantity. Make a pint of fluid extract as directed (1330). 1612. Extractum Sarsaparillae Compositum Fluidum, U. S. — Com- pound Fluid Extract of Sarsaparilla. — Sarsaparilla in No. 30 powder \2% ounces av., Liquorice Root in No. 30 powder 2 ounces av., Sassafras Bark in No. 30 powder 1 % ounces av., Mezereum in No. 30 powder l / 2 ounce av., Glycerin 1 % fl.ounce, Alcohol, Water, each a sufficient quantity. Mix the Glycerin with 6 fl. ounces of Alcohol and 10 fl. ounces of Water, and having moistened the mixed powders with 8 ounces of the mixture, macerate for 24 EXTRACTA FLUIDA — FLUID EXTRACTS. 485 hours in a close vessel ; transfer to the water-bath percolator, pack firmly, pour upon them the remainder of the mixture and set in a warm place for two days ; then heat very moderately and after one hour begin to percolate slowly, adding to the drugs, after the liquid has ceased to drop, Alcohol and Water mixed in the proportion of one part of Alcohol to two parts of Water, and continuing the heat and percolation until the drugs are exhausted. Re- serve the first 13 fl. ounces that pass, evaporate the remainder to a soft extract, which dissolve in the reserved portion, and add enough of the menstruum last used to make a pint of the fluid extract. Lastly, after standing a few days filter through muslin. 1613. Fluid Extract Skullcap Compound. — Skullcap in No. 20 powder 6 2 /i ounces av., Cypripedium in No. 40 powder 4 ounces av., Hops, Wild Lettuce, each in No. 20 powder 3 ounces av., Alcohol 2, Water 1, a sufficient quantity. Make a pint of fluid extract as directed (1221). 1614. Fluid Extract Senna Compound. — Senna in No. 30 powder 8% ounces av., Rhubarb in No. 20 powder 4 ounces av., Jalap, Mandrake, each in No. 50 powder 2 ounces av., Alcohol 2, Water 1, a sufficient quantity. Make a pint of fluid extract as directed (1221), 1615. Fluid Extract Spikenard Compound — Compound Fhdd Extract of Ar alia. — Spikenard Root, Yellow Dock Root, Burdock Root, Guaiac Wood, Sassafras Bark, each in No. 20 powder iy z ounces av., Southern Prickly-Ash, Elder Flowers, Blue Flag Root, each in No. 30 powder 2 ounces av., diluted Alcohol a sufficient qnantity. Make a pint of Fluid Extract as directed (1330). 1616. Fluid Extract Squill, or Scilla Compound. — Squill in No. 20 pow- der, Senega in No. 40 powder, each 8^ ounces av., Water of Ammonia y z fl. ounce, Alcohol 2, Water 1, a sufficient quantity. Make a pint of Fluid Extract as directed (1221), and add the Water of Ammonia. 1617. Fluid Extract Stillingia Compound. — Stillingia, Turkey Corn, each 4 ounces av., Elder Flowers, Blue Flag, Pipsissewa, each 2 ounces av., Coriander Seed, Prickly-Ash Bark, each 1 ounce av., all in No. 30 powder, Alcohol 2, Water 1, a sufficient quantity. Make a pint of Fluid Extract as directed (1221). 1618. Fluid Extract Wild Cherry Compound.— Wild Cherry in No. 20 powder 8% ounces av., Hoarhound, Wild Lettuce, each in No. 20 powder 3 ounces av., American Hellebore, Bloodroot, each in No. 40 powder 1 ounce av., Alcohol 2, Water 1, a sufficient quantity. Make a pint of Fluid Extract as directed (1221). Other Compound Fluid Extracts. — The foregoing formula? for Com- pound Fluid Extracts represent nearly all that are at present quoted by manufacturers, but other combinations will, no doubt, be added, and it is only necessary for the intelligent druggist to follow the data here given to prepare any Compound Fluid Extract that may be desired. EXTRACTA FLUIDA — FLUID EXTRACTS. Green Plant Fluid Extracts. Fluid Extracts prepared from recently gathered herbs, barks, flowers, roots, etc., have been extensively advertised by manu- facturing houses, and some of them are deservedly popular with physicians. Although they cannot have the same uni- formity of strength as Fluid Extracts prepared from dry drugs, yet many of them are stronger and better, especially such as depend for their medicinal value upon volatile principles, which would be lost by the process of drying. As there is no stand- ard of strength established for green plant Fluid Extracts except that the liquid shall be saturated with the medicinal properties of the drug, the following general formula, which is adapted for making all of them, is given. These Fluid Extracts are called by some manufacturers concentrated or specific tinctures : 1619. General Formula for Green Plant Fluid Extracts. The fresh drug, cut, bruised, crushed, dessicated, or otherwise reduced to proper fineness for macerating and percolating, a convenient quantity, Alcohol a sufficient quantity. Having reduced the drug to the proper fineness, pack it in the water- bath percolator, pour sufficient Alcohol upon it to saturate and cover it, and set in a warm place for 2 days ; then heat very moderately, and after one hour begin to percolate slowly, and continue until the liquid ceases to drop. Reserve this portion and continue the percolation with Alcohol until the drug is exhausted. Distill the Alcohol from this last portion until the residue is reduced to the consistence of thin syrup, which add to the reserved portion to complete the fluid extract. The Alcohol remaining in the drug after percola- tion may be recovered by distillation. The following are the drugs from which Green Plant Fluid Extracts are usually prepared. The * denotes that the drug should be macerated as soon as gathered, the + denotes that it should be partly EXTRACTA FLUIDA — FLUID EXTRACTS. 487 dried before macerating, and the £ denotes that the recently gathered drug should be dried or nearly dried before making up. Herbs should be gathered when in flower, roots and barks in the autumn or early spring: No. LATIX NAME. COMMON NAME. PART USED. | 1620 Chinese Sumac Root bark, crushed, f 1621 Star Grass, Unicorn . . . 1622 Amygdalus Persica Common Peach Leaves, bruised. * 1623 Arum Triphvllum Indian or Wild Turnip. Cormus, mashed.* 1624 Asclepias Tuberosa Pleurisy or White Root. Root, crushed, f J 625 Baptisia Tinctoria Wild Indigo Root, crushed, f 1626 Berberis Aquifolium Oregon Grape, Root, crushed. % 1627 1628 Cimicifuga Racemosa. . . . Cactus Grandiflora Root, crushed, f Fresh flowers, bruis'd.* Fresh Plant, or 1629 Cannabis Sativa American Hemp Plant, bruised. * 1630 1631 Cereus Bonplandi Chelidonium Majus Garden Celandine Leaves, bruised. * 1632 1633 Chionanthus Virginicus. . Collinsonia Canadensis. . . Bark, crushed. + Root, crushed. { Stone Root, Ox Balm. . 1634 Corydalis Formosa Turkey Corn or Pea . . . Root, crushed, \ 1635 Cypripedium Pubescens. . Lady's Slipper Root, cut and crushed. f 1636 1637 1638 Epilobium Paulustre Eridiction Glutinosum. . . Verba Santa Leaves, bruised. * 1639 Eryngium Aquaticum. . . . Water Eryngo Root, crushed. * 1640 Euonymus Atropurpureus Wahoo Bark, crushed. \ 1641 Euphorbia Ilipericifolia. . Large Spotted Spurge. . Leaves, bruised. * 1642 Frankenia Grandifolia . . . Verba Rheuma Plant, cut. 1643 Gelsemium Sempervirens. Yellow Jasmine Root, crushed, j 1644 Gossypium ... Cotton Root Bark, crushed. \ 1645 Gnndelia Robusta Herb, bruised. * 1 640 1647 Helonias Diocia 1648 Iris Versicolor Blue Flag 1649 luglans Cineria Butternut 1050 Leptandra Virginica Culver's or Black Root. Root, crushed. \ 1651 Lobelia Inflata Lobelia Herb, bruised. * 1652 Lycopus Virginicus Macrotys Racemosa 1 l.nuthera Biennis 1653 1654 Root, crushed, f Plant, bruised. * Evening Primrose 1655 Penthorum Sedoides Virginia Stone Crop . . . Herb, bruised. * [656 I'liyto'acca Deoandra. . . . Poke, Skoke or Garget. Root, crushed. | lb 5 7 Polygonum Punctatum. . . Water Pepper I lerb, bruised. | 1658 I'olyinnia Uvedelia Bearsfoot, Leaf Cup. . . Root, bruised. * 1659 Populus Candicans Balm or Balsam Gilead. Buds, bruised. * idhl) I'telia Trifoliata Bark, crushed. | Leaves, bruised. |- 1661 Rhus Toxicodendon Poison Oak or Ivy 1662 Rhus Aromatica Aromatic Sumach Root bark, crushed. * 1664 Senecio Aureus Stillingia Sylvatica Stillingia, Oueen's Root Root, crushed. | Root, crushed. \ 1661 Symplocarpus Fostidus. . . 1 abbage [667 L'huja Oo identalis [668 V n. ,1111111 Viride American 1 Icllebore . . . Root, ci nshed. * [66g \ ibunura Prunifolium. . . . Black I law Root bark, crushed, f 488 EXTRACTA FLUIDA — FLUID EXTRACTS. Acetic Fluid Extracts. A few Fluid Extracts made with Acetic Acid, instead of an Alcoholic menstruum, have some merit and reputation ; as they are all made by the same general formula and with the same menstruum it is unnecessary to repeat the formula for each. 1670. General Formula for Acetic Fluid Extracts. To complete the formula for any Acetic Fluid Extract, substitute the name of the drug and the required fineness of powder in the following general formula : The Drug in No. powder, . . . 1673 ounces av. Acetic Acid, 16 fl. ounces. Water, a sufficient quantity. Moisten the powder with the Acetic Acid, and macerate in a closed earthenware, or glass vessel, for twenty-four hours ; transfer it to the water-bath percolator, pack moderately, pour upon it a pint of water, and heat at once ; after one hour begin to percolate adding water to the drug and continuing the heat and percolation until 14 fl. ounces have passed, which re- serve. Turn off the heat and continue the percolation with Water until the drug is exhausted. Evaporate the last portion to two fl. ounces and add to the reserved portion to make a pint of the Fluid Extract. After standing a few days filter through muslin. The following drugs are those from which Acetic Fluid Extracts are usually prepared. They may be made from any other drugs which yield their virtues to Acetic Acid. No. 1671 1672 1673 1674 1675 LATIN NAME. Digitalis Ergota Lobelia Sanguinaria Scilla COMMON NAME. Foxglove Ergot Indian Tobacco . . . Bloodroot Squill Part Used Leaves. . . Fungus . . Herb Root Bulb EXTRACTA FLUIDA — FLUID EXTRACTS. 489 To make the 1870 Vinegars of these Fluid Extracts mix two fl. ounces with 14 fl. ounces of water. To make the 1880 Vinegars, mix 1% fl. ounces of these Extracts with enough water to make a pint. To make Syrup of Squill, mix 1 fl. ounce of the Acetic Fluid Extract of Squill with 15 fl. ounces of Syrup. Aqueous Fluid Extracts. In this class of Fluid Extracts are included all those in which water is mainly employed for extracting their medicinal virtues, and in which Alcohol would be objectionable, either as a menstruum, or for the uses required. In some, however, Alcohol is added as a preservative. But few Aqueous Fluid Extracts are used, but it is evident that a larger variety might be employed with advantage by the profession. Any drug which yields its medicinal value to water may very properly be exhibited in an Aqueous Fluid Extract, and the formulae which follow will be sufficiently ex- plicit for making any preparation of this kind that may be desired. Several Aqueous Fluid Extracts are given in the Br. P. under the name of Liquid Extracts 1676. Fluid Extract Bael Fruit — Belce Fructus, Bengal Quince, sEgle Marmelos, Indian Bael. — Bael Fruit, cut in pieces, 16 ounces av., Water, 12 pints, Alcohol, 3 fl.ounces. Put the Bael Fruit loosely in the water-bath percolator, pour upon it 4 pints of Water and macerate in a warm place for 12 hours, then draw off the liquid by the stop-cock and reserve. Pour on the drug again 4 pints of Water, macerate for two hours and draw off as before. Mix the liquids, evaporate them by gentle heat to 14 fl.ounces, and after straining add 3 fl.ounces of Alcohol to preserve the extract and complete the measure. This is an astringent aromatic demulcent, officinal in the British Pharmacopoeia under the name Liquid Extract of Bael, but little used in this country. 1677. Fluid Extract of Broom Tops, Aqueous — Sarotliamnus Scopa- rius. — Broom Tops, in No. 20 powder, 10- ( ounces av., Glycerin, 5 fl.ounces. Water, a sufficient quantity. Moisten the drug with 10 ounces of Water and macerate for 24 hours in a warm place ; then pack moderately in the water- bath percolator, pour upon it a pint of Water, heat moderately, and after 490 EXTRACTA FLUIDA — FLUID EXTRACTS. one hour begin to percolate, adding Water to the drug and continuing the heat and percolation until the drug is exhausted. Evaporate the percolate to 10 fi.ounces, filter and add through the filter enough Water to make n fi.ounces, then add the Glycerin to make a pint of the tiuid extract. 1678. Fluid Extract Cascara Sagrada, Aqueous — Rhamnus Pru- sJu'na. — Cascara Sagrada Bark in No. 30 powder 1673 ounces av., Glycerin 5 fi.ounces, Water, a sufficient quantity. Mix the Glycerin with a pint of Water and having moistened the powder with 10 ounces of the mixture, macerate for 24 hours in a warm place; then pack moderately in the water- bath percolator, pour upon it the remainder of the mixture, heat moderately, and after one hour begin to percolate, adding Water to the drug and con- tinuing the heat and percolation until the drug is exhausted. Evaporate the percolate, by means of a water-bath to a pint, and after standing a few days filter through muslin. The Br. P. directs Liquid Extract of Cascara Sagrada to be made by boiling 1 pound av. of the bark in successive quan- tities of Water till exhausted, then evaporating the strained liquors to 12 ounces and adding 4 ounces Alcohol. A fluid extract of Cascara Sagrada is also made with Diluted Alcohol as a menstruum, but the Aqueous Extract seems to contain all the valuable medicinal properties of the drug. 1679. Fluid Extract Golden Seal, Aqueous — Hydrastis without Alcohol. Fluid Hydrastis. — Golden Seal (Hydrastis) in No. 30 powder, 1673 ounces av., Glycerin 6 fi.ounces, Water, a sufficient quantity. Mix the Glycerin with 10 ounces of Water, moisten the powder with 8 ounces of the mixture, and macerate for 24 hours in a warm place ; transfer to the water- bath percolator, pack moderately, pour the remainder of the liquid upon it and set in a warm place for two days, then heat moderately and after one hour begin to percolate, adding Water to the drug and continuing the heat and percolation until 13 fi.ounces have passed, which reserve. Turn off the heat and continue the percolation with Water until the drug is exhausted. Evaporate this last portion to 3 fi.ounces, which add to the reserved portion to make a pint of the fluid extract, and after standing a few days filter through muslin. 1680. Fluid Extract Ipecac, Aqueous. — Ipecac in No. 30 powder 167/3 ounces av., Glycerin 6 fi.ounces, Water, a sufficient quantity. Moisten the powder with 12 ounces of Water and macerate for 24 hours, then pack moderately in the water-bath percolator, pour upon it a pint of Water and heat moderately at once. After one hour begin to percolate slowly, adding Water to the drug, and continuing the heat and percolation until the drug is exhausted. Evaporate the percolate to 10 fi.ounces, filter, and add enough Water through the filter to make 10 fi.ounces; then add the Glycerin to make a pint of the fluid extract. This formula makes a preparation which is essentially the same as the officinal fluid extract ; but it is much easier and less complicated to prepare. To make Syrup of Ipecac, mix 1 fl. ounce of this extract with 1 5 fi.ounces of Syrup. EXTRACTA FLUIDA — FLUID EXTRACTS. 491 1681. Fluid Extract Liquorice, Aqueous — For Quinine Mixtures, etc. — Liquorice Root in No. 20 powder 16^ ounces av., Glycerin 5 fl. ounces, Water of Ammonia 3 fl.ounces, Water, a sufficient quantity. Mix the Water of Ammonia with 8 ounces of Water, moisten the drug with the mixture and set in a warm place for one day, then pack moderately in the water-bath percolator, pour upon it a pint of Water, heat at once, and after one hour begin to percolate slowly, adding Water and continuing the heat and perco- lation until the drug is exhausted. Reserve the first y 2 pint that passes, evaporate the remainder to 3 fl.ounces ; mix it with the reserved portion, and add the Glycerin to make a pint of fluid extract. After standing a few days filter through muslin. This is an excellent adjuvant for quinine and other bitter medicines. Liquid Extract of Liquorice of the Br. P. is made by exhausting 1 pound av. of Liquorice Root with Water by successive maceration and pressures, straining the liquors, evaporating to a sp. gr. of 1. 1 60 when cold, and adding l /o of its volume of rectified spirit. To make Elixir of Liquorice for quinine mixtures, mix two fl.ounces of this Fluid Extract with six fl.ounces of Syrup of Wild Cherry and half a pint of simple elixir. To make Syrup of Liquorice, mix two fl.ounces of the Fluid Extract with 14 fl.ounces of Syrup. 1682. Fluid Extract of Opium, Aqueous. — Powdered Opium, 4 ounces av., Glycerin, 5 fl.ounces, Water, a sufficient quantity. Pour 8 ounces of Boiling Water upon the Opium, and after macerating for 2 hours, having covered the perforated diaphragm of the water-bath percolator with a coarse piece of muslin, pour the mixture upon it, heat to about 185 F. and begin to perco- late, adding Water to the drug and continuing the heat and percolation until the drug is exhausted. Evaporate the percolate by means of a water-bath until it is reduced to 10 fl.ounces, filter and add enough Water through the filter to make the measure 1 1 fl.ounces, then add the Glycerin to make a pint of the Fluid Extract. Each minim of this Extract represents about % grain ( >pium. Manufacturers have no definite standard for Fluid Extract Of < >pium, many of them making it only the same strength as the Tincture. The Br. P. directs Liquid Extract of Opium to be made so that the fin- ished product shall contain 5 per cent, of Opium. 1683. Fluid Extract Senega, Aqueous — For making Syrup of Senega. -Senega Root in No. 20 powder, 167^ ouncesav., Glycerin, 5 fl.ounces, Water of Ammonia, }{ fl.ounces, Water, a sufficient quantity. Moisten the powder with 10 ounces of Water and macerate for 24 hours, then pack moderately in the water-bath percolator; pour upon it a pint of Water, heat very moder- ately and after one hour begin to percolate, adding Water to the drug and continuing the heat and percolation until the drug is exhausted. Evaporate the percolate to 10 fl.ounces, add the Ammonia and strain through muslin, adding through the strainer enough Water to make the measure 11 fl.ounces, and then add the Glycerin to make a pint of the Fluid Extract. In evaporating this Extract quite ;i precipitate of albuminous and starchy matter is formed ; when the Water of Ammonia is added the valuable pot- 492 EXTRACTA FLUIDA — FLUID EXTRACTS. tion of this precipitate, Polygalic Acid, is dissolved, and the remainder, which is worthless, is retained on the filter. To make Syrup of Senega mix 2 rl.ounces of this Extract with 14 fl.ounces of Syrup. 1684. Fluid Extract Senna, Aqueous. — Senna, in No. 12 powder, 16^ ounces aw, Glycerin, 5 fl.ounces, Water, a sufficient quantity. Pour upon the Senna 4 pints of hot Water and steep with gentle heat for two hours, pour off the Liquid, press the drug gently, and reserve the liquid ; pour two pints more of hot water upon it, steep for half an hour, pour off and press as before, adding the liquid to the reserved portion. Again pour on two pints of Water, steep, pour off and press as before, adding the liquid to the re- served portion. Evaporate the liquid to 10 fl.ounces, strain, add through the strainer enough Water to make 1 1 fl.ounces, and then add the Glycerin to make a pint of the Fluid Extract. Aqueous Fluid Extract of Senna does not "gripe " as does that made with a partly Alcoholic menstruum. Senna leaves may be percolated first with Alcohol, to remove the principles which produce griping, and a fluid extract may then be made with Water or Diluted Alcohol, in the ordinary manner. Etherial Fluid Extracts. Among the first Fluid Extracts that were officinal in the U. S. were a number of preparations made with ether as a men- struum that are now classed as oleoresins. Manufacturers have furnished several Etherial Fluid Extracts which have had more or less reputation, but none are now official and they are rapidly going out of use, mainly because ether is an unstable and disagreeable vehicle for the exhibition, of medicine. As Etherial Fluid Extracts may, however, be required, we give the following : 1685. General Formula for Etherial Fluid Extracts. To complete the formula for any Fluid Extract in this class put the name of the drug and the fineness of powder required in the following formula : The Drug, in No. powder,. . . 167^ ounces av. Ether, ) Alcohol, \ each, a sufficient quantity. EXTRACTA FLUIDA — FLUID EXTRACTS. 493 Moisten the powder with from 6 to 8 fl. ounces of the Ether and pack quickly and firmly in the water-bath percolator, pour upon it sufficient Ether to saturate and barely cover the drug, and, having covered closely, set in a warm place for two days, then pour hot Water in the water-bath surrounding the per- colator, and after one hour begin to percolate, adding Alco- hol to the drug and continuing the percolation until the drug is exhausted. Reserve the first 14 fl. ounces that pass, evapo- rate the remainder by distillation to 2 fl. ounces and add to the reserved portion. The Alcohol remaining in the drug may be recovered by distillation. The following drugs are those from which Etherial Fluid Extracts are usually prepared. They may be made from any other drugs which contain Oleoresins or principles best soluble in Ether. No. LATIX NAME. COMMON NAME. Part Used. Powder No. 1686 Whole fly . 60 1687 1638 1689 60 Digitalis Digitalis or Foxglove. . . Ergota Ergot Leaves Fungus 60 60 Fluid Extracts of Gums, Resins, Etc. Liquid Extracts. This class of preparations (which are not in fact Fluid Extracts as the term is generally applied, but which might much more properly be called Liquid Extracts) seem superflu- ous, ;m< ounces av., Alcohol a sufficient quantity. Mix the Asafetida with an equal bulk of rice chaff and pack moderately in the water-bath percolator ; pour upon it sufficient Alcohol to saturate and cover the drugs, and set in a warm place for seven days ; then heat very moder- ately and after one hour begin to percolate, adding Alcohol to the drug and continuing the heat and percolation until a pint of the Fluid Extract has passed. This preparation seems entirely unnecessary, and would not be given here except that several manufacturers quote such a Fluid Extract for making Tincture of Asafetida. To make Tincture of Asafetida mix 5^ fl.ounces with 11 fl.ounces of Alcohol. 1693. Fluid Extract Benzoin — Liquid Extract of Benzoin. — Benzoin in No. 50 powder, 8J/3 ounces av., Alcohol, a sufficient quantity. Mix the powder with a pint of Alcohol and macerate in a warm place for 3 days, then, having covered the perforated diaphragm of the water-bath percolator with a piece of coarse muslin or burlap, pour the mixture upon it, heat mod- erately for two hours ; then begin to percolate slowly, adding Alcohol to the drug after the percolate has ceased to drop, and continuing the heat and per- colation until a pint of the Fluid Extract is obtained. To make Tincture of Benzoin mix 6 fl.ounces of this Fluid Extract with 10 fl.ounces of Alcohol. 1694. Fluid Extract Benzoin Compound — Liquid Extract of Benzoin Compound. — Benzoin, in No. 50 powder, 6^ ounces av., Purified Aloes. No. 50 powder, 1 ounce av., Storax, \ x / 2 ounces av., Balsam Tolu, 2% ounces av., Alcohol, a sufficient quantity. Mix the gums with a pint of Alcohol and macerate in a warm place for 3 days, then, having covered the perforated diaphragm of the water-bath percolator with a piece of coarse muslin or bur- lap, pour the mixture upon it, heat moderately for two hours ; then begin to EXTRACTA FLUIDA — FLUID EXTRACTS. 495 percolate, adding Alcohol to the drugs when the percolate has ceased to drop, and continuing the heat and percolation until a pint of the Fluid Ex- tract is obtained. To make Compound Tincture of Benzoin mix 4 fl. ounces of this Fluid Extract with 12 fl. ounces of Alcohol. 1695. Fluid Extract of Catechu — Liquid Extract of Catechu. — Cate- chu, in coarse powder, %y$ ounces av., Alcohol, 4 fl. ounces, Water, a suffi- cient quantity. Mix the Catechu with a pint of Water, and heat it on a water-bath until the Catechu is dissolved ; strain through coarse muslin and evaporate the liquid to 12 fl. ounces; when cool add the Alcohol, strain through muslin and add enough Water through the strainer to make a pint of the Fluid Extract. To make Compound Tincture of Catechu mix 3^ fl. ounces of this Ex- tract with t-Yt. fl. ounces of Fluid Extract of Cinnamon and enough Diluted Alcohol to make a pint. 1696. Fluid Extract of Guaiac — Liquid Extract of Guaiac. — Guaiac Resin, in coarse powder, 8 ';{ ounces av., Alcohol, a sufficient quantity. Mix the Guaiac with 12 ti. ounces of Alcohol in a wide mouth bottle, and heat moderately on a water-bath for 3 hours, then strain through muslin ; add enough Alcohol through the strainer to make a pint of the Fluid Extract. To make the Tincture, mix 5^ flounces with 10;^ fl. ounces of Alcohol. 1697. Fluid Extract Kino — Liquid Extract of Kino. — Kino in No, 40 powder, 6 ounces av., Glycerin, 4 fl. ounces, Alcohol, a sufficient quantity. Mix the Glycerin with 8 fi.ounces of Alcohol and, having mixed the Kino with the liquid in a wide mouth bottle, stop tightly, and heat gently on a water-bath until the Kino is dissolved, then strain through muslin and add through the strainer enough Alcohol to make the measure a pint. Two fi.ounces of this Extract mixed with 1 1 fl ounces of Alcohol and 3 11. ounces of Water makes the officinal tincture. 1698. Fluid Extract Liquorice Extract — Liquid Extract of Liquorice. — Extract Liquorice, in No. 50 powder, 8 ounces av., Alcohol, 4 fi.ounces, Water, a sufficient quantity. Mix the Liquorice with a pint of Water and heat it on a water-bath until the Liquorice is dissolved : strain through muslin and evaporate to 12 11. ounces; when cool add the Alcohol; strain through muslin, and add through the strainer enough Water to make a pint of the fluid extract. 1699. Fluid Extract Myrrh — /./'quid Extract of Myrrh. — Myrrh in moderately fine powder 8^ ounces av., Alcohol, a sufficient quantity. Mix the Myrrh with an equal bulk of rice chaff, pack it moderately in the water- bath percolator, pour upon it a pint of Alcohol and set in a warm place for seven days ; then heat very moderately, and after one hour begin to percolate slowly, adding Alcohol to the drug and continuing the heat and percolation until 14 11. ounces have passed, which reserve. Turn off the heat and con- tinue the percolation with Alcohol until the drug is exhausted. Distill the Alcohol from this last portion until only two ounces remain, which add to 496 EXTRACTA FLUIDA — FLUID EXTRACTS. the reserved portion to make a pint of fluid extract. To make Tincture of Myrrh, mix $% fl. ounces of this fluid extract with enough Alcohol to make a pint. 1700. Fluid Extract Opium — Liquid Extract of Opium. — Opium in coarse powder 4 ounces aw, Alcohol 8 fl. ounces, Water 8 fl. ounces, Diluted Alcohol, a sufficient quantity. Mix the Opium with half a pint of Water, and having covered the perforated diaphragm of the water-bath percolator with a piece of burlap pour the mixture upon it and set in a warm place for two days, then heat to about So C. ( 176 F.) for four hours, add half a pint of Alcohol, and after half an hour begin to percolate, adding Diluted Alcohol to the drug and continuing the heat and percolation until 14 fl.ounces have passed, which reserve. Continue the percolation with Diluted Alcohol until the drug is exhausted. Distill the Alcohol ()4 the measure) from this last portion and evaporate the residue to a soft extract, which dissolve in the reserved portion and add enough Diluted Alcohol to make a pint of the fluid extract. To make Tincture Opium, U. S., 1870, mix $% fl.ounces of this fluid extract with enough Diluted Alcohol to make a pint. To make Tincture Opium, U. S., 1880, mix b% fl.ounces of this fluid extract with enough Diluted Alcohol to make a pint. There is no particular standard among manufacturers for making this fluid extract, many of them making it of the same strength as Tincture of Opium. We have adopted this standard because it seems best adapted to the wants and uses of druggists. Four minims represents a grain of Opium. 1701. Fluid Extract of Opium, Deodorized — Liquid Extract of Opium, Deodorized. — Opium in coarse powder 4 ounces av., Gasoline (Petroleum Ether), 8 fl.ounces, Alcohol, 4 fl.ounces, Water, a sufficient quantity. Mix the Opium with a pint of Water, and having covered the perforated diaphragm of the water-bath percolator with a piece of burlap pour the mixture upon it and set in a warm place for two days ; then heat to about 85° C. (185 F.) for four hours, and begin to percolate, adding Water to the drug and continuing the heat and percolation until the drug is exhausted. Evaporate the percolate to half a pint, and when cool mix with it, in a quart bottle, half a pint of Gasoline, and agitate them frequently during 24 hours ; then filter the mixture through a calico strainer, without pressure, and afterward pour the Gasoline from the purified solution ; evapo- rate by water-bath until no odor of Gasoline remains ; filter, and add to the filtrate 4 fl.ounces of Alcohol and enough Water to make a pint of the fluid extract. To make the 1870 strength Deodorized Tincture of Opium, mix 5>£ fl.ounces of this fluid extract with 3 fl.ounces of Alcohol and enough Water to make a pint. To make the 1880 Tincture, mix 6^ fl.ounces of this fluid extract with 3 fl.ounces of Alcohol and enough Water to make a pint. 1702. Fluid Extract Opium, Camphorated — Concentrated Extract of Paregoric. — Powdered Opium 1 ounce av., Benzoic Acid 1 ounce av., Cam- phor % ounce av., Oil of Anise 1 fl.ounce, Alcohol 12 fl.ounces, Water, a EXTRACTA FLUIDA. FEL BOVIS. 497 sufficient quantity. Macerate the Powdered Opium with 2 ounces of hot Water for two hours. Dissolve the Benzoic Acid, Camphor and Oil of Anise in the Alcohol, and having mixed the solution with the pulpy Opium mass, macerate it for seven days, then filter through paper, adding enough Alcohol through the filter to make a pint of the fluid extract. To make Paregoric, mix 1 fl. ounce of this Extract, 1 fl.ounce of Glycerin, and 14 fl. ounces of Diluted Alcohol. This may be colored by adding to it half a fl. drachm of fluid extract of Liquorice Extract. 1703. Fluid Extract Tolu — Liquid Extract of Tolu. — Balsam of Tolu 8 y 3 ounces av., Alcohol, a sufficient quantity. Mix the Balsam with 8 ounces of Alcohol in a wide mouth bottle, and, having stopped it tightly, heat on a water-bath until the Balsam is dissolved ; then strain through muslin and add enough Alcohol through the strainer to make a pint of the fluid extract. To make the 1870 Tincture of Tolu, mix 3X fl. ounces of this extract with enough Alcohol to make a pint. To make the 1880 Tincture, mix 2^ ounces with enough Alcohol to make a pint. FEL BOVIS — OX-GALL. Ox-gall is the fresh fluid obtained from the gall bladder of Bos Taurus. In domestic medicine and the treatment of do- mestic animals, it is considerably used as an ingredient of lini- ments and lotions. In pharmacy it is used to prepare more permanent preparations of Ox-gall, which are as follows, the first two being official in the U. S. 1704. Fel Bovis Inspissatum — Inspissated Ox-gall. — Made by heating fresh Ox-gall 100 parts or 10 ounces to a temperature not exceeding 8o°C. (i76°F.), straining through muslin, and evaporating the strained liquid on a water-bath to 1 5 parts, or 1 y 2 ounce. This is chiefly used as an ingredient in pills. The dose is 5 to 15 grains. 1705. Fel Bovis Purificatus — Purified Ox-gall. — Made by evaporating 3 parts or 16 tl.ounces of fresh Ox-gall on a water-bath to 1 part or s l A fl. ounces ; then adding 1 part or 6 fl. ounces, agitating, and setting aside for 24 hours, then decanting and filtering, distilling off the alcohol and evapo- rating the residue to pilular consistence. The uses and dose are the same as the preceding. 1706. Fel Bovis Preparatus — Prepared Ox-gall. — The liquid Ox-gall is frequently required in liniments, and, as the fresh < >x-gall will not keep, the following formula for a permanent liquid preparation is presented : Ox-gall, fresh, 16 fl. ounces ; Alcohol, 5 fl. ounces ; evaporate the Ox-gall at a temperature not exceeding 80' C. (176 V.) to 12 tl.ounces; add the Alcohol, allow to stand 24 hours, ami decant the clear liquid. 498 FERMENTUM — YEAST. FERRUM— IRON. 1707. FERMENTUM — YEAST. The ferment obtained in brewing beer and by various other processes is a vegetable growth [Cerevisice Fermentum), which varies somewhat with the substance in which it is developed. It appears as a foam or froth upon the surface of the ferment- ing liquid, and is instrumental in converting the sugar of the solution into alcohol with the evolution of C0 3 . It may be cultivated by the addition of a little yeast to any saccharine solution. It is used in medicine as a poultice for gangrene and ulcers and is given in diabetes. In the form of Vienna Yeast, which is prepared by fermenting an infusion of maize and rye with barley malt, and preserved in various other forms,, it is a well known article of household use. FERRUM — IRON. Symbol, Fe ; Atomic weight, 55.9: Sp. gr. 7.84. Iron is the most useful, abundant, and widely distributed of the metals, and in pharmacy, as well as in the arts, holds the first place for utility and value. It occurs in nature in the form of ores, and is only prepared in metallic form on a large scale. It melts at about 3300 F. Heated with carbon it forms steel. It combines chemically with all the non-metals except hydrogen and nitrogen, and with most of the metals and the acids, forming a great variety of important salts. In the metallic state Iron is employed in pharmacy in the form of fine bright annealed iron wire, which is chosen on account of its purity and cheapness. Reduced Iron in the form of powder is also employed for some purposes. In manufac- turing chemicals in a large way coarser iron is used and the salts obtained purified by various means. Iron is the base of two important series of salts, ferrous and ferric, in the former acting as a dyad and in the latter as a hexad. Ferrum Pulveratum — Poivdered Iron — is official in the G. P. and is considerably used in European countries. It is FERRUM — IRON. 499 made from good cast iron and contains some carbon. It is known as Limatura Martis Prceparata. The following are the official Iron salts : 1708. Ferrum Redactum. Reduced Iron. Sub-carbonate of Iron is first thoroughly washed with water until freed from all traces of sulphate of sodium, then cal- cined until free from moisture, and placed in a reduction tube heated to. dull redness, through which a current of purified hydrogen gas is made to pass for from 5 to 8 hours, or until the oxygen of the iron salt has completely combined with the hydrogen and escaped in the form of steam, leaving the re- duced metallic iron in the form of a fine grayish powder. Uses. — Reduced Iron or Quevenne 's Iron by Hydrogen, as it is frequently called, is used in pharmacy for making pills, lozenges, etc., and may be used instead of iron-wire for making fine preparations, but is too expensive for general use. The dose is from 2 to 5 grains. 1709. Ferri Arsenias, Br. Arseniate of Iron. This is prepared according to the Br. P., by dissolving 20^ ounces av. of Sulphate of Iron in about one gallon of water, and 15^ ounces av. of Arseniate of Sodium, dried at 300 F., in about 6 pints of water, mixing the solutions and adding to the mixture 4^ ounces av. of Bicarbonate of Sodium dissolved in a little distilled water. The mixture is then thoroughly stirred and the precipitate allowed to settle, and washed as is directed for washing precipitates (page 44), until the washings show no reaction with a dilute solution of chloride of barium. The precipitate is then collected, drained, squeezed, and dried • Hi porous bricks in a warm-air chamber, at a temperature not ding ioo° F. Uses. This salt is used as an alterative chalybeate, in doses of ,',; to ' j grain. 500 FERRUM — IRON. 1710. Ferri Carbonas Saccharatus. Saccharated Carbonate of Iron. This salt is official in the U. S., Br., and G. Pharmacopoeias, the method of preparing being slightly different in each, but the resulting preparation being about the same. The U. S. formula is : Sulphate of Iron, .... 10 parts or 10 ounces. Bicarbonate of Sodium, . . 7 parts or 7 ounces. Sugar, in fine powder, ... 16 parts or 16 ounces. Distilled Water, a sufficient quantity. The Sulphate of Iron is to be dissolved in 40 fl. ounces of hot distilled Water, and the Bicarbonate of Sodium in about 6 pints of warm distilled Water. The solutions are to be filtered separately while hot, and the Iron solution gradually added to the solution of Soda, and the resultant precipitate washed with boiling distilled Water as directed (page 44), until the washings give no reaction with test solution Chloride of Bar- ium. The precipitate is then to be collected, drained quickly and pressed, and mixed with the sugar in a porcelain capsule, then evaporated by means of a water-bath to dryness, reduced to powder, and kept in small, well-stopped vials. It contains about ten per cent, of Iron. This should not be mistaken for the Snbcarbonate of Iron, also called Carbonate of Iron, which was formerly official. Uses. — This salt is used as an Iron tonic, in doses of from 5 t° 30 grains. 171 1. Ferri Chloridum. Chloride of Iron — Ferric Chloride. Fe 2 Cl 6 .i2H 2 0. This is official in the U. S. P., and is prepared as follows: Iron Wire, cut in fine pieces 15 parts or 4 ounces av. Hydrochloric Acid, ... 86 parts or 19 fl. ounces. Nitric Acid, Distilled Water, each a sufficient quantity. FERRUM — IRON. 501 Put the Iron Wire into a quart flask and pour upon it 54 parts or 12 fl. ounces of the Hydrochloric Acid, previously- mixed with 25 parts or 6 fl. ounces of Water. Let the mixture stand until effervescense ceases, then heat to boiling and filter the solution through paper, adding a little boiling distilled Water to the Iron Wire in the flask to rinse it, and passing the rinsing through the filter. To the filtered liquid add 27 parts or 6 fl. ounces of Hydrochloric Acid and pour the mixture slowly and gradually in a stream into 8 parts or 12 fl. drachms of Nitric Acid ; heat by means of a sand-bath until nitrous fumes cease to be evolved, then test a small portion with a freshly-prepared test solution of Ferricyanide of Potassium. If a blue color results add a little more Nitric Acid and evap- orate off the excess as before. Then add the remaining 5 parts or 1 fl. ounce of Hydrochloric Acid and enough distilled Water to make the whole weigh 60 parts or 16 ounces av.,and set aside, covered with glass, until it forms a solid crystalline mass. Finally, break up the mass and keep in glass-stopped bottles, protected from light. Uses. — This salt is used externally as a styptic and in solu- tion as an application for sore throat, diphtheretic growths, ulcers, etc. Also, as a tonic, in doses of 3 to 5 grains. 1712. Ferri Citras. U. S. Citrate of Iron — Ferric Citrate. Fe 2 (C H 5 O 7 ) 3 .6H 2 O. This is directed to be made by evaporating solution of Citrate of Iron, at a temperature not exceeding 6o° C. (140 F.), to the consistence of Syrup, and spreading it on glass so that when dry the salt may be obtained in scales. This salt should not be confounded with the Ammonio- Citrate of Iron, which is very much more soluble. This salt, being very slowly soluble, is used chiefly for mak- ing pills, for which it is better adapted than the soluble salt. The dose is 5 to 20 grains. The solution of Citrate of iron from which this salt is pre- pared yields 50 per cent, of the scaled salt. 502 FERRUM — IRON. 1713. Ferri et Ammonii Citras. Citrate of Iron and Ammonium — Soluble Citrate of Iron — Ammonio-Ferric Citrate. The U. S. P. directs this to be prepared from the U. S. offi- cial solution of Citrate of Iron by mixing 3 parts or 1 pint with 1 part or 7 fl. ounces of Water of Ammonia and evapo- rating the mixture at a temperature not exceeding 6o° C. (140 F.) to the consistence of syrup, which is to be spread upon glass, so that, when dry, the salt may be obtained in scales. It is more commonly known as Soluble Citrate of Iron, and should be used in making elixirs, syrups, and all preparations in which a soluble salt is desired. Uses. — This is the soluble Citrate of Iron which is employed for nearly all purposes, except making pills. The dose is from 5 to 20 grains. 1714. Ferri et Quininae Citras. Citrate of Iron and Quinine. The U. S. P. directs this salt to be made as follows : Citrate of Iron (171 2), . 88 parts or n ounces av. Quinine (Alkaloid), dried at ioo° C. (2 1 2° F.), until it ceases to lose weight, 12 parts or \]/ 2 ounces av. Distilled Water a sufficient quantity. Dissolve the Iron Salt in 160 parts or 19 fl. ounces of Distilled Water, by heating on a water-bath at a temperature not ex- ceeding 6o° C. (140 F.). To this solution add the Quinine and stir constantly until dissolved ; then evaporate the solu- tion at the temperature previously stated to the consistence of syrup, and spread on glass, so that when dry the salt may be obtained in scales. Uses. — This salt contains 12 per cent, of Quinine, is not very soluble and is much used for making Bitter Wine of Iron and other tonics, and for making pills. The dose is from 5 to 10 grains. FERRUM — IRON. 503 Citrate of Iron Quinine and Strychine is not an official salt, but may be made by adding I part or 65 grains of Strychnine (Alkaloid) to the above formula, at the same time the Quinine is added. This contains 12 per cent, of Quinine and 1 per cent. of Iron. It is sometimes used for making Elixirs or Syrups of Iron Quinine and Strychnine, and in making pills. This scale salt and the Citrate of Iron and Quinine, as found in the market, generally contain only 10 per cent, of Quinine. 1 715. Ferri et Strychninae Citras. Citrate of Iron and Strychnine. The U. S. P. directs this salt to be made from : Citrate of Iron and Ammonium, 98 parts, or 490 grains. Strychnine I part or 5 grains. Citric Acid 1 part or 5 grains. Distilled Water ... . . . 120 parts or 1 1 fl. drachms. Make in the same manner as directed for Citrate of Iron and Quinine. It contains 1 per cent, of Strychnine and is used as a bitter tonic in doses of 3 to 5 grains. 1716. Ferri et Ammonii Sulphas. Sulphate of Iron and Ammonium ■ — Ammonio-Ferric Sulphate — Ammonio-Ferric Alum. No process for making this salt is now official, but it may be prepared by heating a pint of Solution of Tersulphate of Iron to boiling and adding to it 2y 2 ounces av. of Sulphate of Am- monium, stirring until dissolved and setting aside to crystal- lize. This salt readily deliquesces in warm weather. It is used as a styptic, generally in solution. 1717. Ferri et Ammonii Tartras. Tartrate of Iron and Ammonium Ammonio-Ferric Tartrate. Dilute 90 parts, or 1 3 fl. ounces, of Solution of Tersulphate of Iron with 900 parts or 10 pints, of cold Water; dilute ~ 2 parts 504 FERRUM — IRON. or 14^ fl. ounces, of Water of Ammonium with 180 parts or 2]^ pints of cold Water. Mix the two liquids and wash the precipitate produced as directed (page 44), until the washings cause but a slight turbidness to test solution of Chloride of Barium. Drain and press the precipitate; dissolve 30 parts or 6 ounces av. of Tartaric Acid in 130 parts or i]4 pints of Dis- tilled Water, neutralize the solution exactly with Carbonate of Ammonium, then add 30 parts, or 6 ounces, more of Tartaric Acid and dissolve by gentle heat ; in this solution while still warm dissolve the moist Iron Precipitate, adding a small por- tion at a time until no more will dissolve, then filter the solu- tion, evaporate the filtrate to the consistence of syrup and spread upon glass, so that when dry the salt may be obtained in scales. Uses. — This salt is used as a mild iron tonic in doses of 5 to 20 grains. 1718. Ferri et Potassii Tartras. Tartrate of Iron and Potassium — Potassio-Ferric Tar- trate, U. S. — Tartrated Iron, Br. Mix 13 fl. ounces of Solution Tersulphate of Iron with 9 pints of cold Water. Mix 15 fl. ounces of Water of Ammonia with 2 pints of cold Water, add the Iron Solution to the Ammonia solution, precipitate, wash, drain, etc., as directed in the previous formula. Put the drained precipitate into a stone ware or porcelain vessel, and add to it 3 pints of dis- tilled Water, heat the mixture on a water-bath to a tempera- ture not exceeding 6o° C. (140 F.), add to it 6 ounces av. of Bitartrate of Potassium, and stir until the iron precipitate is dissolved, filter while hot and let the filtrate stand in a cool place for 24 hours, then stir it well and cautiously add just enough Water of Ammonia to dissolve the precipitate. Evaporate the solution to the consistence of a thick syrup, and spread upon glass so that, when dry, the salt may be obtained in scales. This is a mild, ferruginous tonic, and may be given in doses of 10 to 30 grains. FERRUM — IRON. 505 1719. Ferri Hypophosphis. Hypoplwsphite of Iron — Ferric Hypophosphite. Fe 2 (H 2 P0 3 ) 6 . No official process is given for making this salt ; but the most convenient method is by the double decomposition of Sulphate of Iron and Hypophosphite of Calcium. 480 grains of pure Ferrous Sulphate in Crystals is dissolved in a pint of hot Water and the solution added to a solution of 326 grains of Hypophosphite of Calcium in a pint of cold Water. Sul- phate of Calcium is precipitated and ferrous hypophosphite held in solution, the solution is evaporated, and the ferrous becomes a ferric salt, known as Hypophosphite of Iron. Uses. — This salt is given in the form of pills or powders, and is somewhat used in making solutions and syrups of the Hypophosphites but it is not very soluble. The dose is 3 to 10 grains. 1720. Ferri Iodidum Saccharatum. Saccharated Iodide of Iron — Saccliarated Ferrous Iodide. The U. S. P. directs this preparation to be made as follows: Iron Wire, cut fine, ... 6 parts or 60 grains. Iodine, 17 parts or 170 grains. Distilled Water, 20 parts or 3 fl. drachms. Sugar of Milk, 80 parts or 800 grains. Mix the Iron, Iodine and distilled Water in a thin glass flask, shake the mixture occasionally until the reaction ceases and the solution has acquired a green color, and lost the smell of Iodine ; then filter through a wetted filter into a porcelain capsule containing 40 parts or 400 grains of Sugar of Milk. Rinse the flask and Iron Wire with a little distilled Water and pass the rinsings through the filter into the capsule, and evaporate on a water-bath, stirring constantly until a dry mass remains. Transfer the mass quickly to a heated iron mortar containing the remainder of the Sugar of Milk and rub them 506 FERRUM — IRON. well together. Transfer at once to dry bottles, which must be well stopped and kept cool and dark. Uses. — This salt is not very stable after it is opened, and is apt to decompose with the liberation of Iodine. It is used in making pills and in powders, and may be given in doses of i to 5 grains. Iodide of Iron in the form of a solution is official in the G. P. and is made by mixing Powdered Iron 30 parts, with Water 100 parts, and gradually adding Iodine 82 parts, with constant stirring. The solution is then filtered and a little water added through the filter. This is a liquid, which may be evaporated to a mass Fel 2 when required for pills. The Iodide of Iron — Fel 2 — Formerly official in the Br. P. was prepared by mixing i 1 /, ounce of Iron Wire with 3 ounces of Iodine and 12 ounces of Water in a flask, heating gently for 10 minutes, and then boiling until the froth becomes white. The solution is then rapidly filtered through a calico filter and boiled down until a drop solidifies upon cooling. Tasteless Iodide of Iron in the form of a salt is made after a process patented by J. Cruse, by adding Citrate of Sodium or Potassium to the solution as above prepared, sufficient to deprive it of its peculiar ferruginous taste, and then evaporat- ing. It is used in making several tasteless preparations of Iodide of Iron. 1 72 1. Ferri Lactas. Lactate of Iron — Ferrous Lactate. Fe(C 3 H 6 3 ) 2 ,3H 3 0. No official process is now given for making this salt, but it was formerly prepared by mixing 240 grains of Iron filings with Lactic Acid 1 fl. ounce and distilled water a pint, heating the mixture by water-bath, and adding a little distilled water from time to time to preserve the measure. When the action has ceased, filter the solution while hot and set aside to crys- tallize ; after two days decant the liquid, collect the crystals, FERRUM — IRON. 507 wash them with a little alcohol and dry on bibulous paper. More crystals may be obtained by evaporating the poured off liquid and again crystallizing. Uses. — Lactate of Iron is given for the same purpose as other mild Iron salts. It is also used for making some syrups and elixirs. The dose is from I to 5 grains. 1722. Ferri Oxalas. Oxalate of Iron — Ferrous Oxalate. FeC 2 4 .H 2 0. This salt may be made by dissolving 960 grains of Sulphate of Iron in a quart of water; 436 grains of Oxalic Acid in a pint of water, adding the Iron solution to the Acid solution, and washing the precipitate which results as directed (page 44), then drying it by gentle heat. It is but little used in medicine; the dose is 2 to 3 grains. 1723. Ferri Oxidum Hydratum. Hydratcd Oxide of Iron — Ferric Hydrate. Solution of Tersulphate of Iron, 10 parts or 6 fl. ounces. Water of Ammonia, .... 8 parts or Syi fi. ounces. Water, a sufficient -quantity. Dilute the Water of Ammonia with 20 parts or 1 pint of cold water, and the Iron solution with 100 parts or 5 pints of cold water; add the Iron solution, with constant stirring, to the Ammonia solution and wash the precipitate which results as directed (page 44). Then press and add enough water to the mass to make the whole weigh 20 parts or 1 pound av. This is known as moist Oxide of Iron. Uses. — When freshly prepared this is used as an antidote to Arsenical poisoning, and for detannating preparations as elixirs, etc., which are to be combined with salts or solutions of Iron. It loses its value by standing. The Br. P. directs Hydrated 1'eroxide of Iron to be prepared with solution of soda instead of Ammonia; but the result is the same. FERRUM — IRON. 1724. Ferri Oxidum Hydratum cum Magnesia. Hydrated Oxide of Iron witJi Magnesia. This U. S. official is intended to be kept conveniently at hand as an antidote for arsenical poisoning. The ingredients are to be mixed when wanted for use. Solution Tersulphate of Iron, 1, 000 grains, or 1^ fl. ounce. Magnesia {Calcined), . 1 50 grains. Water a sufficient quantity. Mix the solution with twice its weight of water, and keep the mixture in a well-stopped bottle properly labelled. Rub the magnesia with water to a smooth thin mixture, transfer to a quart bottle properly labelled and fill the bottle with water- When wanted for use mix the two liquids by adding the mag- nesia mixture gradually to the Iron solution, and shaking them well together. Uses. — In arsenic poisoning this mixture as thus prepared is freely given, the whole quantity sometimes being used. 1725. Ferri Phosphas. Phosphate of Iron — Ferric Phosphate. This new U. S. official Iron Salt in scales being soluble, is intended to fill the place of the gray powder, which has form- erly been used as Phosphate of Iron (Ferrous Phosphate), which was insoluble. Citrate of Iron, 5 parts or 5 ounces av. Phosphate of Sodium, ... 6 parts or 6 ounces av. Distilled Water, 10 parts or 10 fl. ounces. Dissolve the Citrate of Iron in the Distilled Water by heat- ing on a water-bath, add the Phosphate of Sodium to the solu- tion, and stir until dissolved, then evaporate the solution at a temperature not exceeding 6o°C. (i40°F.) to the consistence of FERRUM — IRON. 509 a thick syrup, and spread upon glass, so that when dry it may be obtained in scales. Uses. — In pharmacy this salt in now much used in making elixirs, syrups, etc., instead of the Pyrophosphate of Iron, which was formerly directed, as it is less sensitive to excess of acid, and more permanent in solution. In medicine it may be given as a mild Iron tonic in doses of 5 to 10 grains. Phosphate of Iron {Ferrous Phosphate) — Fe 3 (P0 4 ) 2 8H 2 0.— The grayish or slate-blue amorphous powder which was form- erly official in the U. S. P. is still retained in the Br. P. It is made by precipitating a solution of 3 ounces of Sulphate of Iron in 30 ounces of Water, with a solution of 2^ ounces of Phosphate of Sodium and ^ ounce Bicarbonate of Sodium in 30 ounces of Water, washing the precipitate and drying at a temperature not exceeding I20°F. 1726. Ferri Pyrophosphas. PyropJiospJiate of Iron — Ferric PyrophospJiate. Citrate of Iron, 9 parts or 9 ounces av. Pyrophosphate of Sodium, . 10 parts or 10 ounces av. Distilled Water, 18 parts or 18 fl. ounces. Dissolve the Citrate of Iron in the Distilled Water by heat- ing on a water-bath, and add to the solution the Sodium salt, stirring until dissolved ; then evaporate the solution to the consistence of a thick syrup and spread upon glass, so that when dry it may be obtained in scales. It is precipitated from its solution by excess of acid. Uses. — This salt has been much used in making elixirs, syrups, solutions, etc., and is also employed in pills and pow- ders. The dose is 2 to 5 grains. 1727. Ferri Sulphas. Sulphate of Iron Ferrous Sulphate. rcS(),.7lL<>. This salt, which is familiarly known as "Copperas," is usually made on a large scale by manufacturing chemists from scrap 510 FERRUM — IRON. iron and oil of vitriol, and purified for pharmaceutical use. It may be made according to the Br. P. by dissolving 4 ounces av. of Iron Wire with 4 fl. ounces (Imperial measure) of Sul- phuric Acid mixed with 30 fl. ounces of distilled Water. When the disengagement of hydrogen gas has nearly ceased, boil for 10 minutes ; then cool, filter the solution and set aside to crys- tallize. After 24 hours collect the crystals, drain on porous bricks, and when dry preserve in stoppered bottles. Uses. — Sulphate of Iron is the basis of many of the other salts of Iron, which are made by decomposing it. It is quite astringent, and is used as a tonic astringent, both externally and internally. The dose is 1 to 2 grains. The commercial Sulphate of Iron (Copperas) is considerably used as a disin- fectant and as a wash for trees to prevent worms and bugs. Sulphate of Iron and Ammonium, or Iron Alum, is a double salt of Iron, used in photography and other arts, and also given for the same purposes as Sulphate of Iron. (See 1716.) 1728. Ferri Sulphas Exsiccatus. Dried Sulphate of Iron. FeS0 4 .H 2 0. This is prepared by heating Sulphate of Iron in an unglazed earthen vessel moderately, until it has effloresced, then increas- ing the heat to 149 C. (300 F.), and maintaining it at that temperature until it ceases to lose weight, and, lastly, reducing it to a fine powder. Uses. — This is chiefly used in making pills, but is some- times prescribed in powders. 1729. Ferri Sulphas Praecipitatus. Precipitated Sulphate of Iron or Ferrous Sulphate — Granu- lated Sulphate of Iron. FeS0 4 7H 2 0. Sulphate of Iron, . . 100 parts or 4 ounces av. Distilled Water, . . . 170 parts or 6y 2 fl. ounces. Sulphuric Acid, ... 4 parts or 38 minims. Alcohol, a sufficient quantity. FERRUM — IRON. 511 Dissolve the Iron salt in the Water, previously mixed with the Acid, and filter the solution ; then pour it gradually, with constant stirring, into an equal volume, about 8 fl. ounces, of Alcohol, and set aside for 24 hours. Collect and drain the precipitate, wash with Alcohol in a funnel until neutral, press and dry without artificial heat and keep in well-stopped bottles. Uses. — This is the same as Sulphate of Iron, but purified, and is more convenient to use in making powders, pills, etc. It is also much less liable to change than the crystalline salt. The dose is 1 to 2 grains. 1730. Ferri Valerianas. Valerianate of Iron — Ferric Valerianate. Fe 2 (C B H 9 2 ) 6 . This may be made by mixing solutions of Sulphate of Iron and Valerianate of Sodium. Ferric Valeriate is precipitated, and may be washed and dried. Uses. — This is but little used in pharmacy and is seldom prescribed. It is given as a tonic nervine, in doses of from 1 to 10 grains. Other Salts of Iron. Besides the foregoing salts of Iron, which are official, are several others, which are more or less used in pharmacy: 1 73 1. Acetate of Iron — Fe g (C 8 H 8 0g) 6 . — Made by dissolving freshly precipitated H yd rated Oxide of Iron to saturation in Acetic Acid, evaporat- ing the solution and crystallizing. 1732. Benzoate of Iron — Fe 2 6C 7 H O 2 .6H 2 O. — By adding a solution of Sulphate of Iron to a concentrated solution of Benzoate of Sodium, col- lecting the precipitate, washing, and drying. 1733. Bromide of Iron — FeBr B .— By adding 2 parts of Bromine diluted with 10 parts of Water to 1 part Iron Wire, and digesting with gentle heat until the liquid assumes a greenish color and the reaction is completed, then filtering and evaporating to dryness. 1734. Carbonate or Subcarbonate of Iron. — By dissolving 4 ounces of Sulphate of Iron and \ l / 2 ounces of Carbonate of Sodium, separately, each in 2 quarts of warm Water, mixing the solutions and washing the precipitate 512 FERRUM — IRON. with sweetened Water, and drying without heat. By exposure this is con- verted into Ferrous Oxide. 1735. Ferrocyanide of Iron — Fe 4 (FeCN R ) 3 . — By dissolving Ferrocyanide of Potassium and adding to it a solution of Sulphate of Iron as long as the blue precipitate is formed, then washing the precipitate and drying. This is known commercially as Prussian Blue. It is made soluble by the addition of 20 per cent, or more of Oxalic Acid, and is then known as Soluble Bhie, an article much sold for laundry bluing. 1736. Nitrate of Iron — Fe 2 (N0 3 ) 6 . — By concentrating a solution of Nitrate of Iron by evaporation and crystallizing. I 737- Oxides of Iron. — With Oxygen Iron combines in several propor- tions. Ferrous Oxide FeO being unknown except in chemistry, as it rapidly absorbs oxygen and passes into a higher oxide. Ferric Oxide Fe 2 3 which is made by burning ferrous sulphate in a crucible until fumes cease to be evolved. This is known commercially as Crocus Mart is, Colcothar, Rouge, Red Oxide of Iron, Venitian Red, etc., as made for various uses. Magnetic Oxide of Iron — Ferroso-Ferric Oxide — Fe 3 4 — a black magnetic Oxide of Iron obtained in various ways and also occurring native ; and some other forms not sufficiently important to notice. The German Pharmacopoeia directs a soluble saccJiarated Oxide of Iron to be prepared by precipitating 30 parts of a solution Chloride of Iron, with a solution of Carbonate of So- dium, adding solution of soda and of Bicarbonate of Sodium, washing the precipitate under water and mixing it with 50 parts of sugar and drying. 1738. Persulphate of Iron — Monsell's Salt. — By evaporating a solution of persulphate or tersulphate of Iron to dryness. Used as a styptic. 1739. Phosphate of Iron, White — Fe 2 2P0 4 4H 2 0.— Besides the official scale salt, Phosphate of Iron (a compound salt) and the former official gray powder, Phosphate of Iron (Ferrous Phosphate), a White Phosphate of Iron (Ferric Phosphate) is made by mixing 4 ounces of solution of normal ferric sulphate, with 1 ounce Acetate of Sodium in solution, and then adding a solution of Phosphate of Sodium, and washing and drying the precipitate. 1740. Sulphide of Iron — FeS. — Made by heating a mixture of 3 parts iron filings with 2 parts of sublimed sulphur in a red hot crucible, into which it is introduced in small portions at a time. This is used for making sulphu- retted hydrogen. Iron Pyrites FeS 2 is another combination of Iron with sulphur, found abundantly in nature. Some other salts of Iron are used occasionally, but are seldom prepared by pharmacists and are of but little interest. Of the unofficial salts of Iron not previously mentioned the more important are the Lacto- Phosphate, Sali- cylate, Succinate, Sulpho-Carbolate, Malate, and Tannate. Dialysed Iron in scales, is mentioned on page 273. and the various solutions of Iron among the solutions. FLUORINE. GELATINA — GELATIN. 513 FLUORINE. Symbol F. ; Atomic weight, 19. The element Fluorine has until recently resisted all attempts to isolate it, but its isolation has lately (November, 1886,) been accomplished by M. H. Moissan of Paris, who obtained it as a colorless inflammable gas, from anhydrous fluoric acid, by electrolysis. It is classed chemically with the halogens, chlor- ine, bromine, and iodine, as its compounds are similar. It is chiefly known by its compound with hydrogen, Hydro- fluoric Acid, which reacts with metals, forming salts called Fluorides. It also combines with boron and silicon forming gaseous compounds. 1741. Hydrofluoric Acid — HF. — This is prepared by pouring concen- trated Sulphuric Acid upon finely powdered Fluor Spar in a capacious leaden retort, gentle heat is then applied and the gas which is evolved is col- lected in a leaden receiver surrounded by ice. It is a colorless fluid vaporizing at 59 F., and is chiefly known by its property of corroding glass. It is much used for etching on glass. It must be kept in leaden bottles. GELATINA — GELATIN. When animal tissues, bones, tendons, ligaments, etc., are boiled for some hours in water, and the water allowed to stand sometime after becoming cold, a mass resembling jelly is obtained. The finer varieties of this jelly thus prepared are purified, evaporated to the proper consistence, spread into sheets, dried on nets, and are known as Gelatin. The coarser varieties, made from hoofs, hides and other refuse animal sub- stances, arc made into Glue of various grades. Isinglass, or Fisk-gluc, is a species of Gelatin prepared from the air bladders of certain fish; but common Gelatin is often called Isinglass. Gelatin, prepared in various ways, is largely consumed as an article of food; in the arts it is extensively used for adhesive 514 GELATINA — GELATIN. purposes, for making Gelatin compositions, for making Gelatin plates for photography, etc.; in pharmacy it is employed for coating pills, making capsules, suppositories, etc., for fining wines and liquors, and for many other useful purposes. 1742. Gelatin Capsules.— A solution of 1 part of Cox's or French Gelatine in 4 parts of Water is made by first soaking the Gelatin for an hour or two in the Water, then heating until the Gelatin is dissolved, and straining the solu- tion. Metal molds of the proper shape are then dipped in the solution, which is heated by a water-bath, and when cool, but still pliant, the Gelatin is removed from the molds, and may be filled with any liquid and the orifice closed with a drop of the Gelatin solution, or may be left empty (as they are now largely used) for filling with powdered substances, quinine, etc. For some purposes a small proportion — say 5 per cent. — of glycerin is added to the solution, making them more elastic. Medicinal Pearls, which contain ether, volatile oils, etc., are made of similar material but by different processes. 1743. Gelatin Coating. — For coating pills with Gelatin a solution may be made with Gelatin 2 parts, Gum Arabic 1 part, Water 9 parts. The Gum Arabic must first be dissolved in the Water, the Gelatin soaked with the solu- tion, and the mixture then heated by water-bath and strained. The solu- tion is kept heated by water-bath, and the pills, stuck on needles or pins, are dipped in the solution and revolved in the air until the coating is suffi- ciently firm to remove the pills from the pins. This makes a fine soluble coating for pills. Various Gelatin-coating pill machines are in use. 1744. Gelatin Suppositories. — For making medicated suppositories, bougies, etc., with elastic Gelatin, 3 parts of Gelatin are soaked in 2 parts of Water and then dissolved by heat and 7 parts of Glycerin added. The solu- tion is then strained and the required medicinal substances added, thoroughly mixed, and the mixture poured into molds of suitable shape. If insoluble substances are added, the mixture must be stirred until the moment it is run into the molds, and the molds chilled with ice. Gelatin Suppositories are not so readily soluble as those made with a cacao butter base, and cannot be recommended as a good form of medication. Tannin is incompatible with Gelatin, forming an insoluble compound, therefore cannot well be used in Gelatin Suppositories. 1745. Liquid Glue.— Acids dissolve Glue, and acid solutions of Glue are used as Liquid Glue and Cement, being more convenient to apply in this form. The following formula; may be used : Dissolve 4 ounces of good Glue or Gelatin in a pint of Acetic Acid, by the aid of gentle heat, and add 20 drops of Nitric Acid, 5 drops Oil of Cloves, and 1 ounce Glycerin. Or Dissolve 5 ounces of good glue in a pint of Water, by the aid of heat, and add 1 ounce of Nitric Acid. GLUCOSE AND GRAPE SUGAR. 515 1746. GLUCOSE AND GRAPE SUGAR. Glucose, as it is now known on the market, is a syrup pre- pared by the action of Sulphuric Acid on Starch, aided by heat. The process by which the purified Starch is transformed into Glucose is called conversion, and different grades of conversion produce quite different results. When the Glucose syrup alone is wanted the process of conversion is stopped when the Starch has disappeared, the product being a mixture of Dextrin and Glucose. This is often called Dextrin Syrup or Starch Syrup. When solid Grape Sugar is desired, the conversion is continued longer so as to convert the Dextrin still further into Dextrose or Glucose. Many large manufacturing establishments in this country are now engaged in the manufacture of Glucose and Grape Sugar, which are extensively sold as articles of food and employed by confectioners for manufacturing candy. In pharmacy, Dextrine Syrup or Glucose is employed for sweet- ening preparations in place of cane syrup or sugar, as it is less liable to fermentation. Grape Sugar is used as an excipient for pills, for making masses, etc., as it does not crystallize like cane sugar. Lccvulose, Maltose, Du/cietose, Mannitose, and Galactose are other Glucoses derived from various substances. 1747. Glucosides. A class of neutral principles found in plants, which yield Glucose, C a 1 1 1 ..< >,;. when decomposed are called Glucosides. They comprise a great variety of substances, varying greatly in characteristics, some of them being the active medicinal agents of the plants from which they are derived and others being of no medicinal importance. They consist of Glucosidal resins, Glucosidal tannins, bitter principles, sweet principles, etc., some being soluble in Alcohol or ether, some in water, and some in other liquids. They are vari- ously prepared and may be decomposed into Glucose and derivitive products in several different ways, some by the action of dilute mineral acids, others by alkalies, and others by the action of ferments. A few of the more import- ant ones, as Salicin, Santonin, etc., arc official and are noted under other headings. Their names all terminate with in, although all principles which terminate with in are not Glucosides. As tluy arc so numerous, and pre- sent such varying characteristics, they cannot well be included in a class, but are included with the other general principles of plants. 516 GLYCERINUM — GLYCERIN. 1748. GLYCERINUM — GLYCERIN. Glycerin, as it is found in the market, is a sweet, viscid, col- orless liquid, of about 125 sp. gr. and the consistence of thick syrup. It was first made known by Scheele, in 1779, and was formerly prepared as a by product of the manufacture of lead plaster and soap, being now sometimes called for as Oil of Soap. At present it is made commercially by distillation, the process consisting in decomposing fats by super-heated steam, under high pressure, the stearine of the fats (which is propenyl tristearate) uniting with the elements of water to form Glycerin and Stearic Acid. Chemically, Glycerin is the hydrate of the radical Glyceryl or Propenyl, C 3 H 5 , and is classed with the Alcohols, being known as Glyceric Alcohol, Propenyl Alcohol, or Glycerol. Glycerin is extensively used in the arts for various purposes, and in pharmacy ranks next to Alcohol as a preservative of medicinal solutions and a solvent of medicinal agents. It is employed in making many fluid extracts, both as a preserva- tive and a solvent ; it is used as an addition to solid extracts, keeping them soft and pliable, and in making many solutions, syrups, tinctures, and like preparations. In medicine it is used to allay inflammation and irritation, both external and internal, and it is a familiar household application for chaps, sunburn, etc. It should be somewhat diluted before it is applied, because of its affinity for moisture. The dose intern- ally is a teaspoon ful or more. 1749. Nitroglycerin — C 3 H 5 (NOg) 3 3 . — Made by mixing 1 part of Nitric Acid with 2 parts of Sulphuric Acid and adding to the mixture slowly and with constant stirring, keeping the mixture cooled artificially as low as 8o°F., one seventh of its weight of Glycerin. The mixture is then poured into a large quantity of water and the oily liquid which settles to the bottom washed with water containing an alkali. Uses. — In mining operations Nitroglycerin is extensively used for blasting, also for " shooting " oil and gas wells. Mixed with some inert absorbing sub- stances, which makes it safer to handle, it is known as Dynamite, which is much used for blasting, and in fire-works, etc. In medicine, a 1 per cent, solution of Nitroglycerin is somewhat used for nervous disorders, in very small doses. GLYCERITA — GLYCERITES. 517 GLYCERITA — GLYCERITES. U. S. Glycerina — Glycerines. Br. Glycerites or Glycerines are preparations in which Glycerin is used as the solvent of the medicinal agents, or the medium by which it is exhibited. Two Glycerites are official in the U. S. and eight Glycerines in the Br. Pharmacopoeia. Many more are supplied under various names, as Glycerols, etc., by manufacturing pharmacists. The following are those official in the U. S. and Br. Pharmacopoeias, most of them being intended for external application. Many of those official in the present Br. P. were official in the 1870 U. S. P., but have been deleted. 1750. Glycerinum Acidi Carbolici. Br. Glycerine or Glycerite of Carbolic Acid. Carbolic Acid, 1 ounce av. Glycerin, 4 fl.ounces. Rub them together in a mortar until the Acid is dissolved. 1751. Glycerinum Acidi Gallici. Br. Glycerine or Glycerite of Gallic Acid. Gallic Acid 1 ounce av. Glycerin 4 fl.ounces. Stir together in a porcelain dish and apply a temperature not exceeding 212 F. until complete solution is effected. 1752. Glycerinum Acidi Tannici. Br. Glycerine or Glycerite of Tannic Acid. Tannic Acid 1 ounce av. Glycerin, 4 fl.ounces. Stir them together in a porcelain dish and apply a temperature not exceed- ing that of a water-bath until complete solution is effected. 1753 Glycerinum Aluminis. Br. Glycerine or Glycerite of Alum. Alum, in line powder 1 ounce av. Glycerin 5 fl.ounces. Stir thriii together in a porcelain dish, gently applying heat until solution ted. Set aside and pour off the clear fluid from any deposited matter. 518 GLYCERITA — GLYCERITEJ 1754. Glyceritum Amyli. U. S. Glycerinum Amyli. Br. Glycerite or Glycerine of Starch. The U. S. formula is: Starch 1 part or 1 ounce av. Glycerin 9 parts or 9 ounces av. Rub them together and heat to 140 C. (284 F.), stirring constantly until uniformly gelatinous. The Br. formula is Starch 1 ounce av., Glycerin 5 flounces, distilled Water 3 fl. ounces. Stir them together in a porcelain dish and apply heat, stirring constantly until the starch particles are completely broken and a translucent jelly is formed. The U. S. preparation is of much firmer consistence than the Br. Uses. — Glycerite of Starch is used in pharmacy as an excipient for pills and a body for suppositories, and may be used in making troches and masses. In medicine it is employed as an application to irritated surfaces, chafe, etc. By perfuming with essential oils or bulk perfumes this makes an elegant toilet preparation, which may be sold as Amy line, for uses similar to Cam- phor Ice. 1755. Glycerinum Boracis. Br. Glycerine or Glycerite of Borax. Borax, in fine powder 1 ounce av. Glycerin 4 fl. ounces. Distilled Water, 2 flounces. Rub them together in a mortar until the Borax is dissolved, or heat gently until solution is effected. 1756. Glycerinum Plumbi Subacetatis. Br. Glycerine or Glycerite of Subacetate of Lead. Acetate of Lead 5 ounces av. Oxide of Lead, in powder y/ 2 ounces av. Glycerin, 20 fl. ounces. Distilled Water, 12 flounces. Mix together and boil for fifteen minutes, then filter and evaporate until the Water is dissipated, which may be known when steam no longer rises. I 757- Glycerinum Tragacanthae. Br. Glycerine or Glycerite of Tragacanth. Tragacanth, in powder, no grains or 3 parts. Glycerin, 1 flounce or 12 flparts. Distilled Water \% fl.drachm or 2 flparts. Mix the Tragacanth with the Glycerin in a mortar, add the Water and rub until a translucent homogeneous jelly is produced. GLYCERITA — GLYCERITES. 519 1758. Glyceritum Vitelli. U. S. Glycerite of Yolk of Egg — Glyconin. Fresh Yolk of Egg, by weight 4^ ounces. Glycerin, by weight 5X ounces. Rub the Yolk of Egg with the Glycerin gradually added until they are thoroughly mixed. This is used in pharmacy for making emulsions. Other Glycerites. The following Glycerites are not official in any Pharmaco- poeia, but some of them are considerably used. 1759. Glycerite of Albumen. Albumen, White of Egg, 6 fl.ounces. Glycerin 10 fl.ounces. Mix them thoroughly, allow to stand 24 hours and strain through a cloth strainer. This is a bland application for chap, chafe, or any irritation of the skin. As the Glycerin is absorbed a thin coating of Albumen is left on the surface, which protects it from contact of the air. By adding ]/ 2 ounce of any good bulk perfume to this preparation it makes an elegant toilet article. 1760. Glycerite of Arnica. Fluid Extract of Arnica 2 fl.ounces. Glycerin 6 fl.ounces. Water 4 fl.ounces. Alcohol, 4 fl.ounces. Mix the Fluid Extract, Alcohol, and Water and filter the mixture clear, then add the ( '.lycerin. 1761. Glycerite of Bismuth. Tris-nitrate of Bismuth 1 ounce av. Glycerin 4 11. ounces. Dissolve the Nitrate of Bismuth in the Glycerin, without heat. It is the crystallized Nitrate of Bismuth (312), not the subnitrate, which is directed in this formula. 520 GLYCERITA — GLYCE RITES. 1762. Glycerite of Calendula. Calendula (Marigold Flowers) 3 ounces av. Glycerin 8 flounces. Water, sufficient to make 1 pint. Mix the Glycerin with 8 ounces of Water, moisten the flowers with the mixture and make a tincture by water-bath percolation, adding Water to the drug sufficient to make a pint of the percolate. 1763. Glycerite of Camphor-Chloral. Camphor, in powder, 75 grains. Chloral 60 grains. Oil of Juniper 30 minims. Glycerin 4 fl. drachms. Alcohol, 5 fl. drachms. Mix in a bottle and heat gently, not over 104 F., until dissolved, cool, and keep well stopped. 1764. Glycerite of Carbolate of Iodine. Carbolic Acid, 1 ounce av. Iodine, 1 ounce av. Alcohol, 4 flounces. Water 5 fl. ounces. Glycerin, ' 5 fl. ounces. Dissolve the Carbolic Acid in the Glycerin and add the Water, dissolve the Iodine in the Alcohol and mix the solutions. 1765. Glycerite of Hypophosphites. Hypophosphite of Calcium 256 grains. Hypophosphite of Sodium, 128 grains. Hypophosphite of Potassium 64 grains. Water, 8 fl. ounces. Glycerin, 8 fl. ounces. Rub the Hypophosphites to a very fine powder and dissolve by rubbing in a mortar with successive portions of the mixed Glycerin and Water, previ- ously warmed. When dissolved strain through muslin or filter. A fl. drachm represents 3^ grains of the mixed Hypophosphites. The dose is a teaspoon- ful to a dessertspoonful. It is considerably used in place of the Syrup of Hypophosphites. GLYCERITA — GLYCERITES. 521 1766. Glycerite of Iodine. {Colorless Tincture or Solution of Iodine.) Tincture of Iodine 8 fl.ounces. Hyposulphite of Sodium 1 ounce av. Glycerin, 8 fl.ounces. Rub the Sodium salt to a fine powder and then with the Glycerin until dis- solved, and add the Tincture to the solution, allow to stand, and filter or decant. This is a Glycerite of Iodide of Sodium, but is more familiarly known as Colorless Tincture of Iodine. 1767. Glycerite of Pepsin. Pepsin in scales, or Pure Pepsin 64 grains. Concentrated Lactic Acid 2 fl. drachms. Water 8 fl.ounces. Glycerin 8 fl.ounces. Rub the Pepsin to a powder and then with the Water and Glycerin previ- ously mixed, add the Lactic Acid and allow to stand a few days, with occa- sional agitation, then strain or filter. A fl.drachm contains % grain of pure Pepsin, equivalent to 5 grains saccharated Pepsin. The dose is a teaspoon- ful to a dessertspoonful. 1768. Glycerite of Pepsin and Wafer Ash. Fluid Extract of Wafer Ash (Ptelea) 1 flounce. Glycerite of Pepsin, 15 fl.ounces. Mix them, and, after standing a few days, filter. A fl.drachm represents about 2> l A grains Wafer-Ash bark combined with Glycerite of Pepsin. The dose is a teaspoonful to a dessertspoonful. 1769. Glycerite of Phosphorus. Phosphorus 3 grains. Glycerin 1 pint. Shave the Phosphorus under water and mix with 1 ll.ounce of the Glyce- rin, melt in a water-bath and shake together in a well-stopped bottle ; warm the remainder of the Glycerin to about 120° F. and add to the mixture. A fl.drachm contains about r \, grain Phosphorus. 1770. Glycerite of Quinine. Bisulphate of Quinine 128 grains. Water 8 fl.ounces. Glycerin 8 ll. ounces. Mix the Water and Glycerin and dissolve the Quinine salt by rubbing in a mortar with the mixture. A ll. drachm contains 1 grain of the Quinine salt. T)22 GLYCERITA — GLYCERITES. 1771. Glycerite of Quinine and Strychnine. Sulphate of Strychnine, 2 grains. Glycerite of Quinine, 1 pint. Dissolve the Strychnine salt by rubbing with the Glycerite of Quinine, or add 2 ti drachms solution of Strychnine to a pint of the Glycerite of Qui- nine. A fl. drachm contains 1 grain of Quinine Bisulphate and ^ grain Strychnine Sulphate. Other combinations of Glycerite of Quinine with the salts of Iron, etc., may be made by adding the required salts in solution to the Glycerite of Quinine. 1772. Glycerite of Tar. Tar, Pine or Birch, 1 ounce av. Carbonate of Magnesium 1 ounce av. Glycerin, . . ■ 8 flounces. Alcohol 3 flounces. Water, o fl.ounces. Rub the Carbonate of Magnesium to a fine powder and incorporate the Tar with it. Mix the Glycerin, Alcohol and Water and rub with the mixture in a mortar, then put in a quart jar, allow to stand a few days, and decant and filter the clear portion. This is given for coughs in doses of a teaspoon- ful to a dessertspoonful. J 773- Glycerite of Tar Compound. Fluid Extract of Wild Cherry %. fl. ounce. Fluid Extract of Squill, 80 minims. Glycerite of Tar, 1 pint. Mix them and filter if necessary. The dose is a teaspoonful or more for coughs, etc. 1774. Glycerite of Yerba Santa Compound. Fluid Extract of Yerba Santa, 2 fl.ounces. Fluid Extract Grindelia 1 fl. ounce. Fluid Extract Wild Cherry 1 fl. ounce. Fluid Extract Liquorice 1 fl. ounce. Bromide of Potassium, 160 grains. Salicylic Acid, 80 grains. Tar, 80 grains. Glycerin, 8 fl.ounces. Water 4 fl.ounces. Carbonate of Magnesium, 1 ounce av. Mix the Fluid Extracts and Tar and rub with the Carbonate of Magne- sium in a mortar, mix the Glycerin and Water and rub with the mixture in the mortar, filter and dissolve the Bromide of Potassium and Salicylic Acid in the filtrate. The dose is a teaspoonful or more for cough, asthma, etc. GLYCYRRHIZINU.M AMMONIATUM. HYDRARGYRUM. 523 1775. GLYCYRRHIZINUM AMMONIATUM. A nuiwniated Glycyrrhizin. (MADE BY WATER-BATH PERCOLATION.) Liquorice Root, in No. 20 powder 16 ounces. YVater, \ Water of Ammonia, - each a sufficient quantity. Sulphuric Acid, ) Mix 1 ounce of YVater of Ammonia with a pint of Water and moisten the drug with 6 ounces of the mixture ; pack moderately in the water-bath per- colator, and having poured the remainder of the mixed Water and Ammonia upon it, cover it closely and set in a warm place for one day ; then heat very moderately, and after one hour begin to percolate, adding Water to the drug and continuing the percolation and heat until two pints have passed, or until the drug is exhausted. Add to the percolate slowly (stirring at the same time) Sulphuric Acid, so long as a precipitate is produced ; collect this on a strainer, wash it and redissolve in Water with the aid of Water of Ammonia, filter if necessary, and again add Sulphuric Acid so long as a precipitate is formed. Collect again on a strainer, wash with cold Water as before, and dissolve with just sufficient Water of Ammonia diluted with an equal quan- tity of Water. Finally, pour on plates of glass and set in a warm place to evaporate. The product is in scales. It is used chiefly in solution for mask- ing the taste of disagreeable or bitter medicines. HYDRARGYRUM — MERCURY. Symbol, Hg; Atomic weight, 199.7; sp. gr., 13.59. Mercury, or Quicksilver, is a fluid metal, found chiefly asso- ciated with sulphur in the form of ore, called Cinnabar, in California and other parts of the world. It is obtained by roasting the ore in kilns through which flames are made to pass, which ignite the sulphur and vaporize the Mercury, which is subsequently condensed. It congeals into a solid at — 40 F. Mercury has been known and used since the earliest history of medicine-, wonderful virtues being ascribed to it by the earlier writers and practitioners. It is extensively used in mining operations to separate silver and gold from crushed quartz, sand, etc., which it does by forming an amalgam with 524 HYDRARGYRUM — MERCURY. them. It is employed for making thermometers, barometers, and other philosophical instruments, and, with tin foil, making an amalgam for glass mirrors, etc. Its salts are extensively- employed in the arts, in chemistry, pharmacy, and medicine. It combines with most acids, forming two classes of salts, Mercurous and Mercuric. The following are the combinations and salts of Mercury official in the U. S., Br., and German Pharmacopoeias : 1776. Hydrargyrum Ammoniatum. Ammoniatcd Mercury — White Precipitate. NH 2 HgCl. The U. S. P. directs 10 parts or 1 ounce av. of Corrosive Chloride of Mercury to be dissolved in 200 parts or 20 fl. ounces of warm distilled Water, and the solution to be filtered and allowed to cool. The filtrate is then carefully poured, with constant stirring, into 15 parts, or \ l /i fi. ounces of Water of Ammonia, which should be in slight excess. Then collect the precipitate, drain on a filter and wash twice with 20 parts or 2 fl. ounces of Distilled Water mixed with 1 part or 50 minims of Water of Ammonia. Finally, dry between sheets of bibulous paper at a temperature not exceeding 30 C. (86° F.). The Br. process is about the same. The salt obtained is a Chloride of Mercuric-Ammonium. Uses. — This is used chiefly for making ointment. 1777. Hydrargyrum cum Crete. Mercury with Chalk. The U. S. P. directs Mercury 38 parts or 167 grains, Sugar of Milk 12 parts or 53 grains, Prepared Chalk 50 parts or 218 grains, Ether and Alcohol, each a sufficient quantity. The Mercury, Sugar of Milk and 12 parts or 53 grains of the Chalk are put into a suitable mortar and moistened with a mixture of equal parts of Ether and Alcohol, and briskly triturated. The remainder of the Chalk is gradually added, HYDRARGYRUM — MERCURY. 525 the powder is occasionally moistened with the Alcohol and Ether and the trituration continued until Globules of Mercury are no longer visible under a magnifying power of 10 diameters, and the powder is of a uniform gray color, and dry. The process may be hastened by using Tincture Tolu in place of Alcohol. The Br. P. directs Mercury I ounce by weight, and prepared Chalk 2 ounces by weight, to be rubbed together in a mortar until the Mercury is extinguished and they are uniformly mixed as above. Uses. — This is a mild form of Mercury considerably used for children. The dose is from 3 to 10 grains. Mercury with Magnesia is made in the same proportion and manner and is used for the same purposes. 1778. Hydrargyri Chloridum Mite. Calomel — Mild Chloride of Mercury — Mercurous Chloride — Subchioride of Mercury. Hg CI. No formula nor process of making is given in the present U. S. P., for this salt, but under the heading Subchioride of Mercury the Br. P. directs Persulphate of Mercury 10 ounces, Mercury 7 ounces, Chloride of Sodium 5 ounces, Boiling Dis- tilled Water a sufficiency. The Persulphate of Mercury is to be moistened with some of the Water and rubbed with the Mercury until globules are no longer visible. The Chloride of Sodium is then to be added and thoroughly mixed by trituration. The mixture is then to be sublimed in a suitable apparatus of such si/.e that the Calomel shall fall in a fine powder on the floor instead of adhering to the sides of the vessel. The powder is then to be washed with boiling Dis- tilled Water,and dried at a temperature not exceeding boiling water. Uses. Calomel is used in making several other prepara- tions of Mer*cury, and is the favorite mercurial salt lor internal administration as an alterative and purgative. The dose is l /> rain - or more. 526 HYDRARGYRUM — MERCURY. 1779. Hydrargyri Chloridum Corrosivum. Corrosive Chloride of Mercury — Corrosive Sublimate — Mercuric Chloride — Bichloride of Mercury — Perchloride of Mercury. HgCl 2 . The present U. S. P. does not give the formula nor process of making this salt. The Br. P. under the name Perchloride of Mercury directs 20 ounces of Persulphate of Mercury to be mixed with 16 ounces of Chloride of Sodium and I ounce of Black Oxide of Manganese, and heated together in an apparatus adapted for sublimation, by which the vapors which rise are condensed. Uses. — This salt is used for making several other prepara- tions of mercury and in medicine as a mercuric alterative in doses of -Jg- to l /i grain. It is also extensively employed in weak solutions to destroy zymotic germs, and by surgeons to prevent poisoning during operations. Antidote. — The best antidote for 'poisoning with Corrosive Sublimate is albumen (white of egg). 1780. Hydrargyri Cyanidum. Cyanide of Mercury — Mercuric Cyanide. Hg(CN) 2 . No process for making this salt is given in the present U. S. P., but it may be made from the process formerly official, which is as follows : Dissolve 5 tr.ounces of Ferrocyanide of Potassium in 20 fl. ounces of Water and add the solution to 4^ tr.ounces of Sulphuric Acid, diluted with 10 fl. ounces of Water and con- tained in a glass retort. Distill the mixture nearly to dryness, conducting the vapor into a receiver containing 10 fl. ounces of Water and 3 tr.ounces of Red Oxide of Mercury. Set aside 2 fl. ounces of the distilled liquid and to the remainder add, with agitation, sufficient Red Oxide to destroy the odor of Hydrocyanic Acid, then filter the solution, and having added the reserved liquid evaporate the whole in a dark place, HYDRARGYRUM — MERCURY. 527 in order that crystals may form, which should be kept in a well stopped bottle protected from the light. Uses. — This salt is used as an alterative in Syphilis, in doses of yL to }4 grain. 1781. Hydrargyri Iodidum Rubrum. Red Iodide of Mercury — Biniodide of Mercury — Mercuric Iodide. Hg I,. The U. S. formula is : Corrosive Chloride of Mercury, 9 parts or 1 ounce av. Iodide of Potassium, ... 11 parts or 535 grains. Distilled Water, a sufficient quantity. Dissolve the Mercury salt in 150 parts or a pint of warm Distilled Water and the Iodide in 30 parts or 3 fl. ounces of Distilled Water and filter the solutions separately. Add the Mercury solution to the solution of Iodide of Potassium, con- stantly stirring. Collect the precipitate on a filter, wash it with Distilled Water until the washings cease to give a pre- cipitate with a test solution of Nitrate of Silver, and dry it between sheets of bibulous paper at a temperature not exceeding 40° C. ( 140 F.), and keep in well stopped bottles. The Br. formula is similar. Uses. — This salt is given in doses of ^V to l /% of a grain for syphilis, etc., and is used in making ointments, and other absorbent applications. 1782. Hydrargyri Iodidum Viride. Green Iodide of Mercury — Pro/ iodide of Mercury — Mercurous Iodide. Hg a I a . Mercury 8 parts or i ounce av. Iodine 8 parts or 274 -rains. Alcohol, a sufficient quantity. I'our about 3 parts or ' _. tl. ounce of Alcohol into a mortar containing the Mercury, add the Iodine in successive portions 528 HYDRARGYRUM — MERCURY. and triturate the mixture, adding sufficient Alcohol from time to time to keep the mass constantly moist and taking care that it shall neither become too hot nor be exposed to light during the various steps of the process. Continue the tritura- tion until all the globules of Mercury have disappeared and the mixture has become nearly dry and has acquired a greenish- yellow color. Then add sufficient Alcohol to reduce the whole to a thin paste ; pour this into a bottle, let stand for several days and then wash the Iodide twice with about 50 parts or 8 fl. ounces of Alcohol each time and decant the washings. Transfer the Iodide to a filter and continue the washing with Alcohol until the washings are no longer affected by Hydrosulphuric Acid. Lastly, dry the product in a dark place, between sheets of bibulous paper, at a temperature not exceeding 40 C. (104 F.), and keep in well stopped bottles, protected from light. Uses. — This salt is used as an alterative and absorbent; being milder than the Red Iodide, it is better adapted for internal use. Dose, 1 grain. 1783. Hydrargyri Oxidum Flavum. Yellow Oxide of Mercury — Yellow Mercuric Oxide. HgO. The U. S. formula is : Corrosive Chloride of Mercury, 1 part or 1 ounce av. Solution of Potassa, ... 9 parts or S}4 fl. ounces. Distilled Water, a sufficient quantity. Dissolve the Mercury Salt in 100 parts or about 6 pints of warm, Distilled Water, and filter the solution ; pour the filtrate into the Solution of Potassa previously diluted with 100 parts or 6 pints of Distilled Water, stirring constantly, and set aside for 24 hours: then decant the supernatant clear liquid from the precipitate, and wash the latter repeatedly with Distilled Water until the washings cease to be affected by a test solu- tion of Nitrate of Silver. Let the precipitate drain, and diy it between sheets of bibulous paper in a dark place, at a HYDRARGYRUM — MERCURY. 529 temperature not exceeding 40 C. (104 F.). The British formula is essentially the same, except that Solution of Soda is used. Uses. — In pharmacy this salt is used for making Oleate of Mercury and in making ointments, etc. It is not admin- istered internally. 1784. Hydrargyri Oxidum Rubrum. Red Oxide of Mercury — Red Precipitate — Red Mercuric Oxide. HgO. Although this salt is chemically the same as the preceding one, it presents an entirely different appearance. The present U. S. P. gives no formula for preparing it. The following is the formula of the Br. P.: Mercury, by weight, 8 ounces av. Nitric Acid, 4^ fl. ounces. Water, 2 fl. ounces. Dissolve half the Mercury in the Nitric Acid, diluted with the Water, evaporate the solution to dryness and with the dry salt thus obtained, triturate the remainder of the Mercury until the two are uniformly blended together. Heat the mixture in a porcelain dish, with repeated stirring, until acid vapors cease to be evolved. Uses. — Red Precipitate, as it is most familiarly known, is used in pharmacy for preparing an ointment and for other purposes. It is a favorite domestic application in the form of ointment for Itch, body-vermin, etc. It is not administered internally. 1785. Hydrargyri Persulphas. Persulphate of Mercury — Sulphate of Mercury — Mer- curic Sulphate. HgS0 4 . This salt is official in the Br. P., but not in the U. S. P. It is known commercially as Sulphate of Mercury, and is 530 HYDRARGYRUM — MERCURY. considerably used in batteries for generating electricity. It is made by heating together in a porcelain vessel, with constant stirring, 10 ounces av. of Mercury and 6 fl. ounces Sulphuric Acid until they are combined, and continuing the heat until the moisture has evaporated and a dry, white salt remains. It is a white, heavy crystalline powder, and in British Phar- macy is used for making Perchloride of Mercury and Sub- chloride of Mercury. 1786. Hydrargyri Subsulphas Flavus. Yellow Subsulphate of Mercury — Basic Mercuric Sulphate — Turpcth Mineral. Hg(HgO) 3 S0 4 . Mercury, 10 parts or 2 ounces av. Sulphuric Acid, ... 5 parts or 1 ounce av. Nitric Acid, 4 parts or 4^ fl. drachms. Distilled Water, a sufficient quantity. Upon the Mercury contained in a capacious flask pour the Sulphuric Acid, then gradually add the Nitric Acid previously mixed, with three parts or y 2 fl. ounce of Distilled Water, and digest at a gentle heat until reddish fumes are no longer given off. Transfer the mixture to a porcelain capsule and heat it on a sand-bath, frequently stirring, until a dry, white mass remains. Reduce this to a fine powder and throw it in small portions at a time, and constantly stirring into 200 parts or 2^ pints of boiling Distilled Water. When all has been added continue the boiling for 10 minutes, then allow the precipitate to settle, decant the supernatant liquid, transfer the precipitate to a strainer, wash it with warm, Distilled Water until the washings no longer have an acid reaction, and dry in a moderately warm place. Uses. — This salt was formerly considerably used as an alterative, in doses of ^ to ]/ 2 grain, but is now mostly replaced for internal use by milder mercurial salts. HYDRARGYRUM — MERCURY. 531 1787. Hydrargyri Sulphidum Rubrum. Red Sulpiride of Mercury — Cinnabar — Vermilion. HgS. The Native Red Sulphide of Mercury is called Cinnabar, but the manufactured article is usually called Vermilion. It is extensively used as a red pigment and is made by different manufacturers of different grades of brilliancy and value, the Chinese being considered the finest. The U. S. P. of 1870 directed it to be made by melting 8 ounces of Sulphur, and gradually adding 40 ounces of Mercury, with constant stirring, continuing the heat until the mass begins to swell, then removing the vessel from the fire and covering it closely, to prevent from inflaming. When the mass is cold it is rubbed into a powder and sublimed. In medicine this is sometimes used as a fumigation, a small portion being put upon coals or a red hot shovel and the fumes inhaled. Other Salts of Mercury. The foregoing official Salts of Mercury embrace nearly all that are used to any extent in Pharmacy. A few other salts are sometimes employed for various purposes, and are here mentioned : 1788. Acetate of Mercury. — Made by dissolving Oxide of Mercury in Acetic Acid, concentrating and crystallizing. 1789. Arseniate of Mercury.— I iy adding a solution of Arsenic Acid to a solution of Nitrate of Mercury and collecting the precipitate in the usual way. 1790. Bromide of Mercury — Mercuric Bromide — HgBr 2 . — I'.y dis- solving Oxide of Mercury in a hot solution of Hydrobromic Acid, filtering, ■ oncentrating and crystallizing. Mercurous Bromide 1 [gBr. may be made by precipitating a solution of Mercurous Nitrate by a solution of bromide of Potassium. 1791. Carbonate of Mercury — Hg 8 CO 8 . — By precipitating a solution of Mercurous Nitrate with Acid Potassium Carbonate, and collecting the pitate. 532 HYDROGENUM — HYDROGEN. 1792. Nitrate of Mercury — Hg 2 (N0 3 ) 2 .2H 2 0. — By mixing 4 parts of Mercury with a mixture of 3 parts of Nitric Acid and 1 part of Water, and after 24 hours collecting the crystals. Several other unimportant Salts of Mercury are sometimes used but so- seldom as to require only mention, as Chlorate of Mercury, Chromate of Mercury. Lactate of Mercury, Phosphate of Mercury, etc. HYDROGENUM — HYDROGEN. Symbol, H. ; Atomic Weight, 1 ; Sp. gr., 1. The Element Hydrogen is a colorless, odorless, inflammable gas, the lightest of all known substances. It rarely exists in Nature in a free state, but combined w r ith other substances from which it may be obtained by chemical action. In chemistry it is one of the most important elements, being used as the standard of comparison for all others, its atomic weight being taken as unity. It unites with all the gaseous elements, and a few of the metals and non-metals, forming binary compounds called Hydrides. It is present in Water, in all true acids, and in all organic radicals. Its affinity in the molecules of substances is less than most of the metals and other basic substances, and it is therefore replaced wholly or partly in the molecules by other bases when they are brought together. It forms gaseous, binary combinations with the haloid elements, Bromine, Chlorine, Iodine and Fluorine, the solutions of which in Water are called Hydro- acids, as Hydrobromic Acid, etc. It forms compounds with Antimony, Arsenic, Copper, Phosphorus, Sulphur, Selenium, Silicon and Tellurium. With Oxygen it forms two oxides, Water, H 2 0, and Peroxide of Hydrogen, H 2 2 , and with Nitrogen it unites to form Ammonia, H 3 N. Its compounds with Carbon form an extensive series of radicals, known as Hydrocarbons, among which are included the Alcohol and Benzene radicals, and it is a constituent of all alkaloids and other principles of plants. 1793. — Peroxide of Hydrogen — H,0 2 . — Made by decomposing Peroxide of Barium by Hydrochloric Acid in the presence of ice-cold Water and the precipitation of the newly formed Barium Chloride by means of Sulphate of INFUSA — INFUSIONS. 533 Silver, the Peroxide of Hydrogen remaining in solution. This compound is seldom made except in chemical laboratories. It is a wonderful bleaching agent and has been extensively employed by hair dressers for bleaching hair, making it blonde or golden. Blondine, a proprietary preparation for this purpose, is composed chiefly of this solution. 1794. Hydracids. — The inorganic acids which are formed by the com- bination of Hydrogen with non-metallic elements, and do not contain Oxygen, are known as Hydracids. They are Hydrobromic Acid, Hydro- chloric Acid, Hydrofluoric Acid, Hydriodic Acid, Hydrosulphuric Acid, and Hvdrocvanic Acid. INFUSA — INFUSIONS. Infusions are preparations in which the medicinal strength of the drug is obtained by infusing or steeping it in hot Water without boiling. They were formerly much used, but on account of the superior convenience and greater reliability of fluid extracts and other modern galenicals are now but little employed except by the "old-time" physicians. The present U. S. P. contains but 5 of the 31 infusions that were formerly official. The Br. P. contains 28. As infusions (with the exception of Infusion Digitalis) contain no Alcohol or other preservative, they will keep only for a short time, and must be freshly made when wanted. It has become the custom in this country, when infusions are wanted for prescriptions, to mix the fluid extract of the drug directed, an equivalent quantity, with the Water directed to be used. This practice, although very convenient, is not to be commended. The following are the infusions official in the U. S. P. : x 795- General Formula for Infusions. The U. S. P. gives a general formula for infusions not specified in the Pharmacopoeia, from which they may be pre- pared as follows : The substance coarsely , . , 10 parts or 1 ounce av. 1 omminuted, \ ' Boiling Water ioo parts or 10 fl. ounces. Water, a sufficient quantity. 534 INFUSA — INFUSIONS. Put the substance into a suitable vessel provided with a cover, pour upon it the boiling Water, cover the vessel tightly and let it stand for two hours. Then strain, and pass enough Water through the strainer to make the infusion weigh ioo parts or measure 10 fl. ounces. BY WATER-BATH PERCOLATION. It is evident from the nature of Infusions that the water- bath percolator is the most convenient vessel in which to make them. This formula may be used for making all Infusions which may be prescribed or directed, except those for which formulae are given : The substance, coarsely ground, i part or ounce. Water, sufficient to make . . . io parts or ounces. Having adjusted the perforated diaphragm or strainer in the bottom of a small-sized water-bath percolator, put the substance in the percolator and pour the water upon it. Cover the percolator closely with the cover, and having filled the vessel surrounding the percolator two-thirds full of Water, heat to boiling, continue the heat moderately for half an hour and draw off the liquid by the stop-cock, adding enough Water through the percolator to make io parts of the preparation. 1796. Infusum Brayerae. Infusion of Bray era {Kousso). Brayera, in No. 20 powder, 6 parts or 1 ounce av. Boiling Water, .... 100 parts or 1 pint. Pour the boiling Water upon the Brayera and let it macerate in a covered vessel until cool. This is to be dispensed, powder and all, in doses of from 4 to 8 fl. ounces. IXFUSA — INFUSIONS. 535 1797. Infusum Cinchonae. Infusion of Cinchona. Cinchona, in No. 40 powder, 6 parts or 1 ounce av. Aromatic Sulphuric Acid, 1 part or 75 minims. Water, to make . . . 100 parts or 1 pint. Mix the Acid with 50 parts of Water and moisten the powder with 3 parts of the mixture ; pack it firmly in a conical glass percolator and gradually pour upon it, first, the remainder of the mixture, and afterward, Water until the Infusion weighs 100 parts or measures a pint. The dose is a tablespoonful. 1798. Infusum Digitalis. Infusion of Digitalis. Digitalis, 3 parts or ^ ounce av. Cinnamon, 3 parts or ^ ounce av. Boiling Water, .... 185 parts or 1 pint. Alcohol, 15 parts or 13^ fl. ounce. Pour the Boiling Water upon the mixed powders and macerate for two hours in a covered vessel. Then strain, add the Alcohol, and pass enough Water through the strainer to make the Infusion weigh 200 parts or measure 1 pint. The dose is a teaspoonful or two. 1799. Infusum Pruni Virginianae. Infusion of Wild Cherry. Wild Cherry, in No. 40 powder, . . . 307 grains. Water, sufficient to make a pint. Moisten the powder with 6 fl. drachms of Water and macer- ate tor one hour; then pack firmly in a conical glass perco- lator, and gradually pour Water upon it until a pint of the Infusion is obtained. This Infusion is made with (.old Water because the heat of boiling Water volatilizes the Hydrocyanic Acid, to which its flavor and value is due. The dose is 1 to 2 fl. ounces. 536 INFUSA — INFUSIONS. 1800. Infusum Sennae Compositum. Compound Infusion of Senna — Black Draught. Senna, 6 parts or 1 ounce av. Manna, 12 parts or 2 ounces av. Sulphate of Magnesium, 12 parts or 2 ounces av. Fennel, bruised, ... 2 parts or y^ ounce av. Boiling Water, .... 100 parts or 1 pint. Water, a sufficient quantity. Pour the boiling Water upon the solid ingredients and macerate in a covered vessel until cold. Then strain and add enough Water through the strainer to make the Infusion weigh 100 parts. The Compound Infusion of Senna, Black Draught, or Vienna DraugJit (Wiener Trank) of the German Pharmacopoeia is as follows : Senna, cut, 5 parts, boiling Water 30 parts. Heat them by means of a steam-bath for five minutes, when cold, strain and dissolve in the infusion Tartrate of Potassium and Sodium 5 parts, Manna 5 parts. The dose of Infusion of Senna Compound, as a laxative is from 1 to 2 fl. ounces, as a brisk purgative 4 to 6 fl. ounces. Other Infusions. The following are the official Infusions of the 1885 Br. P. Most of these were formerly official in the U. S. P. The dose of all the following, unless otherwise noted, is from i to 2 fl. ounces: 1801. Infusum Anthemidis — Infusion of Chamomile. — Chamomile Flowers J^ ounce, boiling Distilled Water 10 flounces. Infuse for 15 minutes in a covered vessel and strain. 1802. Infusum Aurantii — Infusion of Orange Peel. — -Bitter Orange Peel cut small ]A ounce, boiling distilled Water 10 fl. ounces. Infuse for 15 minutes in a covered vessel and strain. 1803. Infusum Aurantii Compositum — Compound Infusion of Orange Peel. — Bitter Orange Peel cut small X ounce, Fresh Lemon Peel cut small, 56 grains, Cloves bruised 28 grains, boiling distilled Water 10 fl.ounces. Infuse in a covered vessel for 15 minutes and strain. INFUSA — INFUSIONS. 537 1804. Infusum Buchu — Infusion of Buchu. — Buchu Leaves, bruised l i ounce, boiling, distilled Water 10 ft. ounces. Infuse in a covered vessel for half an hour and strain. 1805. Infusum Calumbae — Infusion of Calumba. — Calumba Root cut small y 2 ounce, cold distilled Water 10 fl. ounces. Macerate in a covered vessel (without heat) for half an hour and strain. 1806. Infusum Caryophylli — Infusion of Cloves. — Cloves bruised % ounce, boiling distilled Water, 10 fl.ounces. Infuse in a covered vessel for half an hour and strain. 1807. Infusum Cascarillae — Infiision of Cascarilla. — Cascarilla Bark in No. 20 powder 1 ounce, boiling distilled Water 10 fl.ounces. Infuse for half an hour in a covered vessel and strain. 1808. Infusum Catechu — Infusion of Catechu. — Catechu in coarse powder 160 grains, Cinnamon Bark bruised 30 grains, boiling distilled Water 10 fl.ounces. Infuse in a covered vessel for half an hour and strain. 1809. Infusum Chiratae — Infusion of Chiretta. — Chiretta, cut small % ounce, distilled Water at 120 F. 10 fl.ounces. Infuse in a covered vessel for half an hour and strain. 1810. Infusum Cinchonae Acidum — Acid Infusion of Cinchona. — Red Cinchona Bark in No. 40 powder }4 ounce, Aromatic Sulphuric Acid 1 rl. drachm, boiling distilled Water 10 fl.ounces. Infuse in a covered vessel for one hour and strain. This is similar to the U. S. Infusion of Chinchona. 181 1. Infusum Cusparise — Infusion of Ctcsparia. — Cusparia Bark in No. 40 powder % ounce, distilled Water at 120 F. 10 fl.ounces. Infuse in a covered vessel for one hour and strain. 1812. Infusum Cusso — Infusion of Kousso. — Kousso in coarse powder yi ounce, boiling distilled Water 8 fl.ounces. Infuse in a covered vessel for 1 5 minutes. Not to be strained. Dose 4 to 8 fl.ounces. This is similar to the U. S. Infusion of Kousso. 1813. Infusum Digitalis — Infusion of Digitalis. — Foxglove Leaves, dried 28 grains, boiling distilled Water 10 fl.ounces. Infuse in a covered vessel for 15 minutes and strain. Dose, 2 to 4 rl.drachms. This is only about half the strength of the U. S. Infusion of Digitalis. 1814. Infusum Ergots — Infusion of Ergot. — Ergot crushed % ounce, boiling, distilled Water, 10 fl.ounces. Infuse in a covered vessel for half an hour and strain. 1815. Infusum Gentianae Compositum — Compound Infusum of Gen- tian.— Gentian Root, sliced, Bitter Orange Peel cut small, of each, 55 grains, Fresh Lemon Peel, cut small % ounce, boiling distilled Water 10 ll.ounces. Infuse in a covered vessel for half an hour and strain. The U. S. 1870 Compound Infusion of Gentian, which is still considerably used, was Gentian x / 2 tr .ounce, Bitter Orange Peel, Coriander Seed, each 60 538 INFUSA — INFUSIONS. grains, Alcohol 2 fl. ounces, Water sufficient to make a pint. The Alcohol was mixed with 14 fl.ounces of Water and the drugs percolated with the mixture. 1816. Infusum Jaborandi — Infusion of faborandi. — Jaborandi, cut small Yz ounce, boiling distilled Water 10 fl.ounces. Infuse in a covered vessel for half an hour and strain. 1817. Infusum Krameriae — Infusion of Rhatany. — Rhatany Root % ounce, boiling distilled Water 10 fl.ounces. Infuse in a covered vessel for half an hour, and strain. 1818. Infusum Lini — Infusion of Linseed. — Linseed 1 50 grains, Dried Liquorice Root, in No. 20 powder 50 grains, boiling distilled Water 10 fl.ounces. Infuse in a covered vessel for two hours, and strain. 1819. Infusum Lupuli — Infusion of Hop. — Hop % ounce, boiling dis- tilled Water 10 fl.ounces. Infuse in a covered vessel for one hour, and strain. 1820. Infusum Maticae — Infusion of Matico. — Matico Leaves, cut small y z ounce, boiling distilled Water 10 fl.ounces. Infuse in a covered vessel for half an hour, and strain. 1821. Infusum Quassia? — Infusion of Quassia.— Quassia Wood, in chips 55 grains, cold distilled Water 10 fl.ounces. Macerate in a covered vessel (without heat), for half an hour, and strain. 1822. Infusum Rhei — Infusion of Rhubarb. — Rhubarb Root, in thin slices % ounce, boiling distilled Water 10 fl.ounces. Infuse in a covered vessel for half an hour, and strain. 1823. Infusum Rosae Acidum — Acid Infusion of Roses. — Dried Red Rose Petals, broken up, % ounce. Diluted Sulphuric Acid 1 fl.drachm, boil- ing distilled Water 10 fl.ounces. Add the Acid to the Water, infuse the petals in the mixture in a covered vessel for half an hour, and strain. 1824. Infusum Senagae — Infusion of Senega. — Senega Root in No. 20 powder yi ounce, boiling distilled Water 10 fl.ounces. Infuse in a covered vessel for half an hour, and strain. 1825. Infusum Sennas — Infusion of Senna. — Senna 1 ounce, Ginger, sliced 28 grains, boiling distilled Water 10 fl.ounces. Infuse in a covered vessel for half an hour, and strain. 1826. Infusum Serpentariae — Infusion of Serpenlary. — Serpentary Root in No. 20 powder X ounce, boiling distilled Water 10 fl.ounces. Infuse in a covered vessel for half an hour, and strain. 1827. Infusum Uvae Ursi — Infusion of Bearberry. — Uva Ursi Leaves, bruised V z ounce, boiling distilled Water 10 fl.ounces. Infuse in a covered vessel for one hour, and strain. IODOFORMUM — IODOFORM. 539 1828. Infusum Valerianae— Infusion of Valerian. — Valerian Rhizome, bruised % ounce, boiling- distilled Water 10 fl. ounces. Infuse in a covered vessel for one hour, and strain. The foregoing Infusions include all that are at present official in the U. S., Br. and G. Pharmacopoeias, and all for which there is generally a demand ; if others are desired, they may be made by the general directions in the beginning of this article. 1829. IODOFORMUM — IODOFORM. CHI3. To prepare Iodoform, Felhol's process is usually chosen as being most economical. Two parts of Crystallized Carbonate of Sodium are dissolved in 10 parts of Water and 1 part of Alcohol, by the aid of gentle heat, 1 part of Iodine is then added to the solution in small portions, and after cooling the crystals are collected, and the solution or mother liquor fil- tered. This is warmed, 2 parts of Carbonate of Sodium are again added, and a current of Chlorine passed rapidly through the mixture as long as Iodoform is separated. The crystals are then washed with a little cold Water and carefully dried. Iodoform is insoluble in Water, but soluble in Alcohol, Ether, Chloroform, etc. It has a peculiar, disagreeable odor, which makes it objectionable in medicines, but this is in a measure overcome by the addition of Oil of Peppermint or other strongly flavored oils. Caff-Iodoform is a mixture of finely powdered Coffee with Iodoform, intended to overcome its disagreeable odor, which it does imperfectly. Uses. — Iodoform is given internally as an alterative, in doses of 1 to 3 grains, but is chiefly used in the form of oint- ment, in suppositories, and as a dusting to sores, ulcers. Syphilitic growths and diseased surfaces. It is also used as a al dressing in the form of Iodoform Cotton, which is made by dissolving 24 grains of Iodoform in a mixture of 4 11. drachms of Alcohol with 2 fl.drachms of Ether, and adding 2 fl.drachms of Glycerin, saturating 360 grains of Purified Cotton with the liquid, and drying by exposure to the air. 540 IODUM— IODINE. IODUM — IODINE. Symbol, I ; Atomic Weight, 126.6; Sp. gr., 4.95. Iodine is a non-metallic element, first discovered by De Courtois, in 1812, examined and described in 181 3, by M. Clement, and assigned a place as an element soon afterward by Sir H. Davy and M. Gay Lussac. It is chiefly obtained from Kelp, the ashes of sea-weeds, obtained off the coast of Scotland, by percolating them with Water, filtering the percolate, concentrating it by evaporation to a small volume, removing the crystalline salts as they form in the liquid during evaporation, and adding finally to the dark- brown liquid residue, which is called Iodine Lye, Sulphuric Acid in excess. After standing, the liquid is decanted, heated to about 140 F., and mixed with Binoxide of Manganese, as much as was used of Acid. The whole is then introduced into a cylindrical leaden still, heat is applied and the vapor of Iodine which rises is condensed in glass receivers. It is then " resublimed," and in this form is furnished to the trade. Iodine, Bromine, Chlorine and Fluorine are classed in chemistry as hologcns (salt-producers). Their characteristics and properties are similar. Iodine unites with the most of the metallic bases, forming a class of salts called Iodides ; with Hydrogen it forms Hydri- odic Acid, which also combines with bases to form Iodides, the Hydrogen being displaced. With Oxygen it forms iodic and periodic anhydrides, which unite with bases in the presence of Water, forming iodates. In pharmacy Iodine is used in the form of tincture, solu- tions and ointments, and for making Hydriodic Acid, Iodo- form and many well-known salts, etc. Medicinally, it is seldom used except in solution or admixture with other substances. The combinations of Iodine with bases are noticed under the basic substances. The following are the combinations of Iodine with Hydrogen and Oxygen, called Acids : Acids of Iodine. 1830. Hydriodic Acid — HI. — A solution of this gas in Water is made by passing a current of Hydrosulphuric Acid gas through a solution of Iodine LAC — MILK. 541 until it acquires a pure yellowish color, and ceases to turn brown on shak- ing. This solution was formerly made by the U. S. process to contain 15 per cent, of real Hydriodic Acid, but is not now official. The Syrup of Hydriodic Acid, which is the only official preparation, contains 1 per cent, of the real Acid. 1831, Iodic Acid or Anhydride — HI0 3 . — This is made by heating 1 part of Iodine with 10 parts of Nitric Acid in a retort until the Iodine is dissolved and fumes cease to be evolved. The solution is then evaporated and the residue heated to 200 F. until all traces of acid are removed. The white powder is Iodic Anhydride. 1832. Periodic Acid or Anhydride — HI0 4 . — By adding 1 part of Iodine to 7 parts of Carbonate of Sodium dissolved in 100 parts of Water, and passing Chlorine into the heated liquid until a precipitate ceases to form. Collect this precipitate, dissolve it in pure Nitric Acid then add Nitrate of Silver, and dissolve the precipitate which forms in hot, diluted Nitric Acid. Concentrate the solution and crystallize, then re-dissolve the crystals in Water and re-crystallize. LAC — MILK. Milk obtained from the mammary glands of the cow, goat, or mare is the source of many important articles employed in pharmacy and medicine. It consists of about 85 per cent, of water and 15 per cent, of solid constituents, the most import- ant of which are butter (327), casein, of which cheese is made, and milk-sugar. The following are the preparations used in pharmacy which are derived from milk: 1833. Condensed Milk. — Made by evaporating Milk in vacuo at a low temperature until most of its water has been vaporized and it is reduced to the consistence of an extract. It is only made by large manufacturing estab- lishments, and is usually put up in sealed cans. It may be used advantage- ously for making emulsions. 1834. Koumiss.— This is milk prepared as a beverage or nutritive drink for invalids. It was first introduced by the Russians, who made it by fer- menting mare's milk, but is now made quite extensively in this country from cow's milk, by adding to one gallon of skimmed sweet Milk 4 ounces of white Sugar and a cake of Vienna Yeast. This is allowed to stand in a warm place for a few hours and is then transferred to pint or quart bottles, which are tightly Stopped and set in a warm place, for a few hours to ferment and then put on their sides in a cool cellar. In about three days it is ready for use. Koumiss does not keep a great while, and when opened, like cham- loses its gas and becomes worthless. Small quantities, as wanted for use. may be drawn from the bottles by a champagne tap. 542 LAMELL/E — DISCS. 1835. Saccharum Lactis— Sugar of Milk— C, gH^O, , .H 2 0.— When the Casein and albuminous matter has been separated from Milk, as in the process of making cheese, there remains a liquid called whey, which con- tains Milk-Sugar in solution. This may be obtained by evaporating the whey, purifying the syrup obtained, and allowing the Milk-Sugar to crystal- lize. The best Sugar of Milk is obtained from goat's milk, but cow's milk yields a good quality when properly treated. Uses. — Milk-Sugar is used in pharmacy as a dilutent to powerful alka- loids and other medicines which are triturated with it to a very fine powder. It is used in making abstracts, powdered extracts, triturations, saccharated pepsin, and many other similar preparations. It is much harder and less soluble than other sugars. 1836. Acidum Lacticum — Lactic Acid — HC 3 H 5 3 . — By standing, Milk becomes sour, or, rather, its milk-sugar is converted by oxidation into Lactic Acid, which may be obtained from it by various processes. It is made, however, by manufacturing chemists from cane sugar by treating it with sulphuric acid until "inverted," then adding caustic soda and heating the mixture until it ceases to precipitate Fehling's solution, showing the absence of sugar. To this, sulphuric acid is then added, which forms sodium sulphate, which crystallizes out. The liquid is then mixed with alcohol, allowed to precipitate, and one half the alcoholic solution heated with car- bonate of zinc until effervescense ceases ; the other half is then added, and, when cool, zinc Lactate crystallizes out, which, when treated with hydrosul- phuric acid, yields sulphide of zinc in crystals, Lactic Acid remaining in solution. Uses. — The salts of Lactic Acid, with bases, are called Lactates, for mak- ing which it is chiefly employed. It is also used in making some solutions, syrups, elixirs, etc., and in medicine to aid digestion, etc. (See 36.) LAMELLA — DISCS. The 1885 Br. P. introduces, under this name, the following preparations : 1837. Lamellae Atropine — Discs of Atropine. — Discs of Gelatine with some Glycerin, each weighing about ^ grain and containing -j-^ grain of Sulphate of Atropine. 1838. Lamellae Cocoainae — Discs of Cocoaine. — Discs of Gelatine with some Glycerin, each weighing about 7 V grain and containing 3^0 grain of Hydrochlorate of Cocaine. 1839. Lamellae Physostigminae — Discs of Physostigimine. — Discs of Gelatine, with some Glycerin, each weighing about -^ grain, and containing ttiVo grain of Physostigmine. LINIMENTA — LINIMENTS. 543 LINIMENTA — LINIMENTS. Liniments in pharmacy are solutions or liquid mixtures intended for external application, and generally applied by rubbing on the skin with friction, for reducing swellings, relieving pain, etc. A great number of proprietary liniments are also recommended for internal use as well as application. Under this heading only, the liniments which are official in the U. S., Br. or German Pharmacopoeias will be noticed. Those popular as proprietary remedies, will be found under The Standard Remedies, etc. The following are the formulae for liniments official in the U. S., Br. and German Pharmacopoeias: 1840. Linimentum Aconiti — Aconite Liniment. — Aconite Root in No. 40 powder 20 ounces av., Camphor 1 ounce av., Rectified Spirit, a sufficient quantity to make 30 fl. ounces (Imperial measure). Mix the Aconite with 20 fl. ounces of the spirit and macerate in a closed vessel for three days, agitating occasionally; then transfer to a percolator, and when the liquor ceases to pass continue the percolation with more of the spirit, allowing the liquor to drop into a receiver containing the Camphor, until the product measures the quantity above stated. Br. 1841. Linimentum Ammoniae — Ammonia Liniment. — The U. S. P. directs Water of Ammonia 30 parts or 3 ounces av. Cotton Seed Oil 70 parts or 7 ounces av., to be mixed together with violent agitation. The I Jr. P. directs 1 part or fl. ounce of Solution (Water) of Ammonia to be mixed with 3 parts or fl.ounces of Olive Oil. The G. P. directs 3 parts Olive Oil, 1 part Poppy Oil and 1 part Water of Ammonia. The French Codex directs 90 parts Almond Oil to 10 parts of 4 F. Water Ammonia. The U. S. preparation has been found defective, as it will not remain mixed without separating. The I!r. formula makes a preparation which solidifies or becomes too thick upon standing for some time. The German contains too much oil for the. Ammonia. ring half Olive I >il with the Cotton Seed Oil. in the U. S. formula, or by .substituting nil of Hemic altogether for the Cotton Seed Oil, a stable and tionable Liniment is produced. This Liniment is popularly known as Volatile Liniment. 1842. Linimentum Belladonnae - Belladonna Liniment. The U. S. formula is, Fluid Extract of Belladonna (root) 95 parts or 9>i fl.ounces 544 LINIMENTA — LINIMENTS. Camphor 5 parts or % ounce av. Dissolve the Camphor in the Fluid Extract. The Br. P. directs a strong tincture of Belladonna Root to be made in the same manner and in the same proportion as is directed for making Linimen- tum Aconiti, and Camphor 1 ounce av. to be dissolved in the tincture thus prepared to make 30 fl. ounces (Imperial measure). 1843. Linimentum Calcis — Lime Liniment. — Solution of Lime 1 part or 2 fl. ounces, Cotton Seed Oil or Olive Oil 1 part or 2 fl.ounces. Mix them by agitation. The U. S. P. directs Cotton Seed Oil, the Br. P. Olive Oil. The 1870 U. S. P. directed equal parts of Lime Water and Flax Seed Oil, which formula is still followed by most druggists. As thus prepared it was popularly known as Carron Oil, deriving its name from the Carron Iron Works, Scotland, where it was extensively used for burns. 1844. Linimentum Camphorae — 'Camphor Liniment, Camphorated Oil. — The U. S. formula is, Camphor 20 parts or 3 ounces av., Cotton Seed Oil 80 parts or 1 2 ounces av. The Camphor is to be dissolved in the Oil. The Br. P. directs Olive Oil in the same proportion in place of the Cotton Seed Oil. The G. P., under the name Oleum Camphoratum, directs 1 part of Camphor to be dissolved in 9 parts of Olive Oil, making a preparation only about two thirds the strength of Camphor as the U. S. or Br. 1845. Linimentum Camphorae Compositum — Compound Camphor Lin- iment. — Br. Camphor 2^ ounces av., Oil of Lavender 1 fl. drachm, strong solution of Ammonia 5 fl.ounces (Imperial measure), Rectified Spirit 15 fl.ounces (Imperial measure). Dissolve the Camphor and Oil of Lavender in the Spirit, then add the solution of Ammonia, gradually shaking them together until a clear solution is formed. 1846. Linimentum Camphorae Ammoniatum — Ammoniated Camphor Liniment. — The G. P. directs Camphorated Oil (see G. P. formula above) 3 parts, Poppy Oil 1 part, Water of Ammonia 1 part. Mix them to a uni- form Liniment by shaking. 1847. Linimentum Cantharidis — Cantharides Liniment. — The U. S. formula is Cantharides in No. 60 powder 15 parts or 2 ounces av., Oil of Turpentine sufficient to make 100 parts or a pint. Digest the Cantharides with 100 parts or 1 pint Oil of Turpentine in a closed vessel, by means of a water-bath, for three hours ; then strain and add enough Oil of Turpentine through the strainer to make 100 parts or 1 pint. 1848. Linimentum Chloroformi — Chloroform Liniment. — The U. S. formula is commercial Chloroform 40 parts or 2 fl.ounces, Soap Liniment 60 parts or S'A fl.ounces. Mix them. The Br. P. directs Chloroform 2 fl.ounces, Liniment of Camphor 2 fl.ounces. 1849. Linimentum Crotonis — Liniment of Croton Oil. — This is official in the Br. P., the formula being Croton Oil 1 fl.ounce, Oil of Cajuput 3^ fl.ounces, Rectified Spirit y/ 2 fl.ounces. LINIMENTA — LINIMENTS. 545 1850. Linimentum Hydrargyri — Liniment of Mercury. — This is offi- cial in the Br. P., as follows : Ointment of Mercury 1 ounce, Solution (Water) of Ammonia 1 fl. ounce, Liniment of Camphor 1 fl. ounce. Mix the Solution of Ammonia with one half the Liniment of Camphor, rub the Mer- curial Ointment with the other half, and mix them together. 1851. Linimentum Iodi — Liniment of Iodine. — This is rather a solu- tion than a liniment. It is official only in the Br. P. Iodine 1% ounce aw, Iodide of Potassium l / z ounce av., Glycerin % ounce av., Rectified Spirit 10 rl. ounces. Dissolve the Iodine, Iodide of Potassium, and Glycerin in the Spirit. 1852. Linimentum Opii — Liniment of Opium. — This is official in the Br. P., being simply a mixture of equal parts by measure of Tincture of Opium and Soap Liniment. 1853. Linimentum Plumbi Subacetatis — Liniment of Subacetate of. Lead. — The U. S. P. directs this to be made with Solution Subacetate of Lead 40 parts or 2 ounces av., Cotton Seed Oil 60 parts or 3 ounces av., by mixing them well together. 1854. Linimentum Potassii Iodidi cum Sapone — Liniment of Iodide of Potassium and Soap. — The Br. P. formula is as follows : Curd Soap cut small 2 ounces av., Iodide of Potassium i>< ounce av., Glycerin 1 fLounce, Oil of Lemon 1 fl. drachm, distilled Water 10 fl.ounces. Dissolve the Soap in the Water and Glycerin by the aid of heat, add the Iodide of Potassium in fine powder and stir while cooling, then rub the Oil of Lemon into the cream- like product. 1855. Linimentum Saponis — Soap Liniment. Liquid Opodeldoc. — The U. S. formula is soap, in shavings 10 parts or 480 grains, Camphor 5 parts or 240 grains, Oil Rosemary 1 part or 48 grains, Alcohol 70 parts or 9 fl.ounces, Water q. s. to make 100 parts or lyi. fl.ounces. The soap is digested in the Water until dissolved. The Camphor and oil are dissolved in the Alcohol ; the solutions are then mixed and filtered. The Br. formula is about the same. In our experience, however, we find that a larger propor- tion of Water is advantageous, and so give the following: Improved Formula — White Castile Soap, dry 4% ounces av., Camphor 1% ounces av., oil Rosemary }< II. ounce, Alcohol 32 fl.ounces, Water 8 the soap in the Water on a water-bath until dissolved; dissolve the Camphor and oil in the Alcohol, then mix the solutions and filter. 1856. Linimentum Sinapis Compositum — Compound Mustard Lini- ment, The I'. S. formula is, Volatile Oil of Mustard 3 parts or 1 fl.dracbm, Extract of Mezereum 2 parts or 40 grains, Camphor 6 parts or 120 grains, Castor Oil 15 parts or 6 fi.drachms, Alcohol, sufficient to make 100 parts 01 \% fl.ounces. Dissolve the extract in 70 parts or 4 fl.ounces of Alcohol, then add the oil <,f Mustard and the Castor oil, and, finally, enough Alcohol t" make 100 parts or 5'.. II. miners. The Br. formula is about the same. 546 LIQUORES— SOLUTIONS. 1857. Linimentum Terebinthinae — Turpentine Liniment. — The U.S. formula is Resin Cerate 65 parts or 13 ounces av., Oil of Turpentine 35 parts or 8 fl. ounces. Melt the Cerate and add the Oil of Turpentine, mixing them thoroughly. The Br. P. directs Soft Soap 2 ounces av., distilled Water 2 fi. ounces, Camphor 1 ounce av., Oil of Turpentine 16 fi. ounces. Mix the Soap with the Water, dissolve the Camphor in the oil, then rub the fluids together until they are thoroughly mixed. The G. P. gives the following: Carbonate of Potassium 6 parts, Soft Soap 54 parts, Oil of Turpentine 40 parts. Mix them. 1858. Linimentum Terebinthinae Aceticum — Liniment of Turpentine and Acetic Acid. — Oil of Turpentine 4 fl. ounces, Glacial Acetic Acid 1 ounce av., Liniment of Camphor, 4 fl. ounces. Mix them. Br. Other Liniments. Other liniments will be found under other headings, as Proprietary Medicines, Standard Remedies, etc. LIQUORES — SOLUTIONS. Under this general classification, a great variety of liquid preparations, widely dissimilar in methods of making, charac- teristics, properties, and strength are included. The Liquorcs of the U. S. P. are chiefly aqueous solutions of Chemical Salts. The Br. P. includes solutions of the gases, ammonia and chlorine, several solutions of salts charged with carbonic acid gas, and some preparations made with alcoholic or other mediums, and the name "solutions" as popularly understood includes preparations in nearly all classes of liquid galenicals. In this department the solutions official in the U. S., Br., and German Pharmacopoeias are first given ; then the solu- tions convenient for use in making elixirs, syrups and other similar preparations; then the test-solutions and such un- official solutions as are frequently called for. Many other solutions are also included under other headings, as ACIDS, Coloring Substances, Dialysates, Glycerites, etc., etc. LIQUORES — SOLUTIONS. 547 The following are the official solutions of the U. S., Br. and German Pharmacopoeias. They are given less prominence than the solutions which are employed for combining with elixirs, syrups, etc. : 1859. Liquor Acidi Arseniosi. Solution of Arsenious Acid — Solution Chloride of Arsenic. The U. S. P. directs : Arsenious Acid in small pieces 1 part or 74 grains. Hydrochloric Acid 2 parts or 135 minims. Distilled Water sufficient to make . . . 100 parts or 1 pint. Boil the Arsenious Acid with the Hydrochloric Acid mixed with 25 parts or 4 II. ounces of Distilled Water, until it is dissolved. Filter the solution and pass enough Distilled Water through the filter to make 100 parts or one pint. The Br. formula, under the name Liquor Arsenici Hydrochloricus, is Arsenious Acid in powder 87 grains, Hydrochloric Acid 2 fl. drachms, Dis- tilled Water a sufficiency to make 20 fl. ounces (Imperial). Uses. — This solution is used as an alterative, the same as Fowler's Solu- tion, in doses of 2 to 5 minims. i860. Liquor Acidi Chromici. Br. Solution of Chromic Acid. The Br. P. gives the following formula : Chromic Acid 1 ounce av. Distilled Water, 3 fl. ounces. Dissolve. This solution is used as an escharotic and caustic. 1861. Liquor Aluminii Acetici. G. P. Solution of Acetate of Aluminium. Sulphate of Aluminium 300 parts. Acetic Acid 360 parts. Precipitated Carbonate of Calcium . . poparts. Water 1 000 parts. Dissolve the Sulphate of Aluminium in 800 parts of Water, add the Acetic A' nl and having triturated the Precipitated Carbonate of Calcium with 2co parts of Water, add it gradually to the solution, stirring constantly. Let the mixture stand 24 hours at the ordinary temperature, stirring frequently; then strain the liquid from the sediment, press the latter without washing it and filter the liquid. 548 LIQUORES — SOLUTIONS. 1862. Liquor Ammoniac. Br. Solution of Ammonia. The 10 per cent, solution of Ammonia Gas, NH 3 , which is known in the U. S. as Water of Ammonia. In the G. P. is called Liquor Ammonii Caustici. See Aqua Ammonia ( 145). 1863. Liquor Ammonias Fortior. Br. Strong Solution of Ammonia. This official of the Br. P. is a 32.5 per cent, solution of Ammonia Gas in Water; the U. S. stronger Water of Ammonia being a 28 per cent, solu- tion. See Aqua Ammonia Fortior (146). 1864. Liquor Ammonii Acetatis. Solution of Acetate of Ammonium. — Spirit of M indereras. The U. S. process for making this solution is to neutralize any convenient quantity of Diluted Acetic Acid with Carbonate of Ammonium, by adding the salt to the Dilute Acid as long as effervescence occurs. As Carbonate of Ammonium contains a variable quantity of Ammonia Gas, definite pro- portions cannot well be given ; but in general 1 ounce av. of Carbonate of Ammonium, if fresh, will neutralize about a pint of Dilute Acetic Acid. The Br. P. directs this solution to be made by mixing 4 fl. ounces of the strong solution of Acetate of Ammonium (1865) with 16 fl.ouncesof Distilled Water. The G. P. directs it to be made by neutralizing Water of Ammonia 10 parts with Acetic Acid 12 parts, or sufficient, and heating to evaporate excess of Ammonia. Uses. — This solution is used as a diaphoretic or diuretic in doses of 4 to 6 fl.drachms. 1865. Liquor Ammonii Acetatis Fortior. Br. Strong Solution of Acetate of Ammonium. Carbonate of Ammonium 5 ounces av. Acetic Acid, a sufficiency, or 13 flounces. Distilled Water, sufficient to make 16 flounces. Crush the Carb. Ammonium and add it gradually to 12 ounces of the Acetic Acid, then add more of the acid until a neutral solution results. To this add sufficient water to make 16 fl. ounces. Uses. — This is a convenient solution to keep on hand for preparing the ordinary solution of Acetate of Ammonia. It is five times as strong as the foregoing. The dose is }i to 1^ drachm. LIQUORES — SOLUTIONS. 549 1866. Liquor Ammonii Anisatus. G. P. Anisated Spirit of Ammonia. Oil of Anise 1 part. Alcohol 24 parts. Solution (Water) of Ammonia, 5 parts. Mix the Oil of Anise with the Alcohol and dissolve, then add the Water of Ammonia. 1867. Liquor Ammonii Citratis. Br. Solution of Citrate of Ammonium. Strong Solution Citrate of Ammonium, 5 fl. ounces. Distilled Water 15 flounces. Mix them. The dose is 2 to 6 fl. drachms. 1868. Liquor Ammonii Citratis Fortior. Br. Stro7ig Solution of Citrate of Ammonium. Citric Acid, 12 ounces av. Strong Solution of Ammonia, Br., a sufficiency, or . 11 fl. ounces. Distilled Water, a sufficiency. Neutralize the Add with the Ammonia, adding sufficient Distilled Water to yield 20 fl. ounces (Imperial) of the product. If U. S. stronger Water of Ammonia is used, a larger quantity will be required. 1869. Liquor Antimonii Chloridi. Br. Solution of Chloride of Antimony — Butter of Antimony — Perchloride of Antimony. Purified Black Antimony 1 pound av. Hydrochloric Acid, Br 80 fl.ounces (Imperial). Place the Purified Black Antimony in a porcelain vessel, pour upon it the Hydrochloric Acid, and, constantly stirring, apply to the mixture, beneath a Que with a good draft, a little heat, which must be gradually augmented as the evolution of gas begins to slacken un' il the liquid boils. Maintain it at this temperature for fifteen minutes, then remove the vessel from the fire and filter the liquid through calico into another vessel, until clear. Boil this down to the bulk of 40 fl. ounces (Imperial) and preserve it in stopped bottles. Uses. -This solution is familiarly known as Butter of Antimony, and is Used as an escharotic for foul ulcers, and for " fouls " of sheep and cattle, etc. In pharmacy it is used for making the Oxide of Antimony. 550 LIQUORES — SOLUTIONS. 1870. Liquor Arsenii et Hydrargyri Iodidi. Solution of Iodide of Arsenic and Mercury — Donovan's Solution. The U. S. formula is: Iodide of Arsenic, 1 part or 74 grains. Red Iodide of Mercury, 1 part or 74 grains. Distilled Water sufficient to make 100 parts or . . . 1 pint. Triturate the Iodides with 15 parts or 2 flounces of Distilled Water until dissolved. Filler the liquid and pass enough Distilled Water through the filter to make 100 parts or 1 pint of the solution. The Br. formula is 45 grains each Iodide of Arsenicum and Red Iodide of Mercury, dissolved in 10 fl. ounces (Imperial) of Distilled Water. Uses. — Donovan's Solution contains about 1 per cent, of each of the iodides, and is employed as an alterative, the same as Fowler's, in doses of 3 to 5 minims. It should be largely diluted when prescribed, and may best be given in the form of an elixir, which see (525). 1871. Liquor Arsenitis Potassii. Solution of Arsenite of Potassium — Fowler's Solution. The U. S. formula is : Arsenious Acid in small pieces, 1 part or .... 74 grains. Bicarbonate of Potassium, 1 part or 74 grains. Compound Tincture of Lavender, 3 parts or . . . 2 fl. drachms. Distilled Water sufficient to make 100 parts or a pint. Boil the Arsenious Acid and Bicarbonate of Potassium in a glass vessel with 10 parts or 1 J^ fl.ounces of Distilled Water until dissolved. Then when cool add the Compound Tincture of Lavender and enough Distilled Water to make 100 parts or a pint of the solution. Then set aside for eight days and filter. The Br. P., under the name Liquor Arsenicalis, directs Arsenious Acid 87 grains, Carbonate of Potassium 87 grains, Compound Tincture of Lavender 5 fl.drachms, Distilled Water a sufficient quantity to make 20 fl.ounces (Imperial). The German formula Liquor Kalii Arsenicosi is the same as the Br. except that Compound Spirit of Balm is used as the flavoring ingredient. Uses. — Fowler's Solution, as it is popularly known, contains 1 per cent, of Arsenious Acid or about 4^- grains in an ounce. It is much employed in medicine as an alterative in doses of three to five minims. It should be largely diluted when given, and is best exhibited in the form of an elixir, which see (524). LIQUORES — SOLUTIONS. 551 1872. Liquor Atropinae Sulphatis. Br. Solution of Sulphate of Atropine. Sulphate of Atropine, 1 part or 9 grains. Camphor Wattr, 99 fl. parts or i6>£ fl. drachms. Dissolve. The strength is 1 to 100. The dose is one to 4 minims. A great variety of Solutions of Alkaloidal Salts may be made in a similar manner to ihis. Some of them are prepared for hypodermic injections and for internal use. 1873. Liquor Bismuthi. Liquor Bismuth — Solution of Bismuth. Citrate of Bismuth and Ammonium . 256 grains. Water of Ammonia, a sufficient quantity, Distilled Water, sufficient to make 1 pint. Rub the Bismuth Salt to a smooth mixture with 2 fl.ounces of Distilled Water, and add Water of Ammonia drop by drop until the salt is dissolved and the solution is clear or nearly clear, then add Distilled Water enough to make a pint, and after standing a few hours filter through paper. This solution is not official in the U. S., but is such as is furnished by manufacturers and prescribed by physicians under this title. Elixir Bismuth (536) contains the same amount of the salt, and is to be preferred to it. The Br. P., under the name Liquor Bismuthi et Ammonii Li/ratis, gives the following : Citrate of Bismuth, 800 grains. Solution (Water) of Ammonia, ) Distilled Water f of each a sufficiency. Rub the Citrate of Bismuth to a paste with a little of the Water ; add the Solution of Ammonia, gradually and with stirring, until the salt is just dis- solved, and dilute with Distilled Water to form 20 fi. ounces (Imperial). Tnis solution contains 5 grains of Citrate of Bismuth in a 11. drachm or about z)A times as much of the Bismuth Salt as the foregoing, and the dose is y 2 to a fi. drachm. In Br. pharmacy it is evaporated over a water-bath to the consistence of a syrup, and spread upon glass in thin layers, to make the Citrate of Bismuth and Ammonium Salt. A strong solution of Citrate of Bismuth and Ammonium for combining wiili elixirs, eic, is also given (1924). 1874. Liquor Calcii Chloridi. Br. Solution of Chloride of Calcium. Chloride of Calcium 88 grains. Distilled Water 1 flounce. Dissolve, and filter if necessary. Dose, 15 to 50 minims. 552 LIQUORES — SOLUTIONS. 1875. Liquor Calcis. Solution of Lime — Lime Water, The U. S. formula is Lime ]/ z ounce, which is to be slaked by the gradual addition of about 3 fl. ounces of Water, a pint of Water is then to be added and the mixture agitated occasionally for half an hour, and allowed to settle. The Water is then to be poured off and thrown away, and 1 gallon of Distilled Water poured upon the remaining precipitate which is to be mixed with it and allowed to settle, when the clear supernatant fluid is ready for use. It contains about 0.15 per cent, of Hydrate of Calcium in solution. The Br. P. directs 2 ounces of slaked Lime to be well washed with water, and the washed Lime to be added to 1 gallon (160 fl. ounces Imperial) of Distilled Water. As Solution of Lime is a saturated solution, the U. S. and Br. preparations are the same strength. Uses. — Solution of Lime, or Lime Water, as it is popularly called, is much used to allay irritation of the stomach, nausea, etc., and externally in the form of liniments, washes, etc., to sooth irritation and inflammation. The dose internally is from ^ to 4 fl. ounces. 1876. Liquor Calcis Chlorinatae. Br. Chlorinated Lime, 1 part or 1 ounce av. Distilled Water, 10 parts or 10 fl.ounces. Mix them well by triturating in a mortar, and set away in a stoppered bot- tle for three hours, with occasional agitation, then Alter through a calico filter until clear. 1877. Liquor Calcis Saccharatus. Br. Saccharated Solution of Lime. Slaked Lime 1 ounce. Sugar 2 ounces. Distilled Water 20 fl.ounces. Mix the Lime and Sugar by trituration in a mortar and add the mixture to a bottle containing the Water; shake occasionally for a few hours, and finally decant the clear liquid for use. The Sugar adds to the solubility of the Lime. Uses. — This solution is given for the same purposes as ordinary Lime Water, the dose being from 15 to 60 minims. The U. S. Syrupus Calcis is a much stronger preparation. See also Stronger Lime Water (852.) 1878. Liquor Chlori. Br. Solution of Chlori7ie — Chlorine Water. This is the Aqua Chlori formerly official in the U. S. P. and still official in the Br. P. under the above title. See page 235. LIQUORES — SOLUTIONS. 553 1879. Liquor Corrosivus. G. P. Corrosive Liquid. Sulphate of Copper, 6 parts. Sulphate of Zinc, 6 parts. Vinegar 70 parts. Solution Subacetate of Lead 12 parts. Dissolve the salts in the Vinegar and add the Solution. This should be freshly prepared for use. 1880. Liquor Epispasticus. Br. Blistering Liquid — Linimentum Cantharides. Cantharides in powder, 5 ounces. Acetic Ether sufficient to make 20 fl. ounces. Mix the Cantharides with 3 fl. ounces of Acetic Ether; pack in the water- bath percolator and allow to stand 24 hours ; then pour Acetic Ether on the drug in the percolator, pour hot water in the water-bath surrounding the percolator, allow to stand an hour, and begin to percolate, adding Acetic Ether to the drug and continue the percolation until 20 fl.ounces have passed. Uses. — This is used in British Pharmacy for preparing Collodium Vesicans (see page 242), and is sometimes applied as it is as a counter-irritant or epis- pastic for neuralgia, etc. 1881. Liquor Ferri Acetatis. Solution of Acetate of Iron — Solution of Ferric Acetate. The U. S. formula is : Solution of Tersulphate of Iron, . . 100 parts or 14^ fl.ounces. Glacial Acetic Acid 26 parts or 4^ fl.ounces. Water of Ammonia 80 parts or 16 fl.ounces. N ater * " * * \ of each a sufficient quantity. Distilled Water, I H The solution of Iron is diluted with 350 parts or 4 pints of cold Water, and added with constant stirring to the Water of Ammonia previously mixed with 200 parts or 2>£ pints of Water. The precipitate is washed as directed, page 44, until the washings cause but a slight precipitate with test solution of Chloride of Barium. It is then drained and pressed as dry as possible and dissolved in the Glacial Acetic Acid, and enough Distilled Water added to the solution to make 100 parts or 1 pint. This solution should have a sp. gr. of 1.160 and contain 33 per cent, of anhydrous Ferric Acetate. It is used mainly for making Tincture of Acetate of Iron. The dose is 3 to 5 minims. 554 LiguoRES — solutions. It is somewhat stronger than the Br. Liquor Ferri Acetatis Fortior, which has sp. gr. 1.127, and is made in the same manner with solution Per- sulphate of Iron 5 fl. ounces, solution of Ammonia a sufficiency, Glacial Acetic Acid 3 flounces, Distilled Water, a sufficiency to make 10 fl. ounces. The Liquor Ferri Acetatis of the Br. P. is a solution of the same strength as the Br. Tincture of Acetate of Iron, made by mixing 1 fl.ounce of the Br. strong solution of Acetate of Iron with enough Distilled Water to make 4 fl. ounces. Its sp. gr. should be 1.031. The German preparation by the same name contains about 5 per cent, of the Iron Salt, and is somewhat stronger than the Br. solution last named. 1882. Liquor Ferri Dialysatus. Solution of Dialysed Iron. This solution is official in the Br. P. The formula will be found on page 272. It should contain 5 per cent, of Oxide of Iron. Liquor Ferri Oxy- chlorate (1887) is frequently sold for Dialysed Iron, as it is much' more readily made. 1883. Liquor Ferri Chloridi. Solution of Chloride of Iron — Solution of Ferric Chloride. The U. S. formula is: Iron in the form of fine wire and cut into small pieces, 1 5 parts, or y/ 2 ounces av. Hydrochloric Acid, 86 parts, or 16^ fl.ounces. Nitric Acid, a sufficient quantity. Distilled Water, a sufficient quantity. Put the Iron Wire into a flask capable of holding double the volume required and pour upon it 54 parts or xoyi fl.ounces of Hydrochloric Acid previously diluted with 25 parts or 5^ fl.ounces of Distilled Water, and let the mixture stand until effervescense ceases ; then heat it to the boiling point ; filter through paper, and, having rinsed the flask and Iron Wire with a little boiling Distilled Water, pass the washings through the filter. To the filtered liquid add 27 parts or 5X fl.ounces of Hydrochloric Acid and pour the mixture slowly and gradually in a stream into 8 parts, or \*/% fl.ounces of Nitric Acid contained in a capacious porcelain vessel. Afrer effervescense ceases, apply heat by means of a sand bath until the liquid is free from nitrous odors. Then test a small portion with freshly prepared test-solution of ferricyanide of potassium. Should this reagent produce a blue color, add a little more Nitric Acid and evaporate off the excess. Finally, add the remain- ing 5 parts, or 1 fl.ounce of Hydrochloric Acid and enough Distilled Water to make 100 parts or 1 pint of the liquid, which contains 37.8 per cent, of the anhydrous salt. Its sp. gr. is about 1 .40. LIQUORES — SOLUTIONS. 555 The Br. Liquor Ferri Perchloridi Fortior, or Strong Solution of Per chlo- ride of Iron, is made in the same manner as the foregoing, but contains a trifle more of the iron salt, 4 ounces av. of Iron Wire being used to produce 17^ fl. ounces (Imperial) of the solution. Sp. gr. about 1.42. The Br. Liquor Ferri Perchloridi, or Solution of Perchloride of Iron, is the same strength as the Br. Tincture of Perchloride of Iron, and is made by mixing 5 fl. ounces of the strong solution of Perchloride of Iron with sufficient Distilled Water to produce after admixture 20 fl. ounces sp.gr. i.n. The dose is 10 to 30 minims. The German Liquor Ferri Perchloridi, or Solution of Perchloride of Iron, is made in a similar manner as the U. S. solution, but is much weaker, containing only 10 per cent, of Iron. Sp. gr. about 1.280. Uses. — The Solution of Chloride of Iron is used chiefly for making Tincture of Chloride of Iron, Dialysed Iron and some other Iron prepara- tions. As the same or similar names are applied to solutions of different strengths it is necessary to understand which one is intended. 1884. Liquor Ferri Citratis. U. S. Solution of Citrate of Iron — Solution of Ferric Citrate. The U. S. formula is : Solution of Tersulphate of Iron, . . 105 parts or \oy z ounces av. Citric Acid 30 parts or 3 ounces av. Water of Ammonia, 84 parts or 8jS^ fl. ounces. Water, sufficient to make . . . . 100 parts or 10 ounces av. To the Water of Ammonia previously diluted with 200 parts or 20 fl. ounces of Cold Water add, constantly stirring, the Solution of Iron previously diluted with 1000 parts or 6 pints of Cold Water. Wash the precipitate which forms as directed, page 44, until the washings cause but a slight cloudiness with test-solution of chloride of barium ; then pour off the Water, drain the pre- cipitate and transfer it to a porcelain dish, add the Citric Ac'd, and heat the mixture on a water-bath to 6o° C. (140 F.), stirring constantly until the pre- cipitate is dissolved. Lastly, filter the liquid and evaporate it at the above named temperature to about 100 parts or 10 ounces av. This solution contains about 35.5 per cent, of the anhydrous salt, equivalent to 50 per cent, of the scaled salt. Uses. — In pharmacy this solution is used for making several other scale salts and solutions of Iron, and is very convenient to use in solutions in place of the scale salt when directed, double the quantity by weight being required. A solution of Citrate of Iron and Ammonium is used for combining with elixirs, syrups, etc., see 1925. 556 LIQUORES — SOLUTIONS. 1885. Liquor Ferri et Quininae Citratis. Solution of Citrate of Iron and Quinine. The U. S. formula is : Citrate of Iron and Ammonium, . . 65 parts or 1 136 grains. Quinine (Alkaloid), dried at ioo° C. (212 F.) 12 parts or 210 grains. Citric Acid, 28 parts or 490 grains. Alcohol 30 parts or 12 rl. drachms. Distilled Water, sufficient to make . 200 parts or 8 ounces av. Dissolve the Citrate of Iron and Ammonium in 200 parts or 8 ounces of Distilled Water contained in a weighed capsule, heat the solution to 6o° C. (140" F.) on a water-bath, add the Citric Acid, and, when dissolved, add the Quinine, stirring the mixture until a perfect solution has been obtained. Evaporate this to 160 parts or 6 ounces av., allow it to cool, add the Alcohol, and finally enough Distilled Water to make 200 parts or 8 ounces av. Uses. — This solution is just half the strength of the scaled salt and is very convenient to use in solutions instead of it when required. Double the quantity by weight must be used as is directed of the scaled salt. It may be used instead of the salt in making elixirs, syrups, wines, etc. The dose is from 10 to 20 minims. 1886, Liquor Ferri Nitratis. Solution of Nitrate of Iron — Solution of Ferric Nitrate. The U. S. formula is as follows : Solution of Tersulphate of Iron, ... 18 parts or 2^ fl. ounces. Water of Ammonia 15 parts or 3 flounces. Nitric Acid, 7 parts or j]/ 2 drachms. is 1 e a er, / eac ^ su ffj c j ent to ma k e IOO p ar t s or 20 ounces av. Water, . . . ) F Dilute the Water of Ammonia with 40 parts or 8 fl.ounces of cold Water and add to it the Solution of Iron previously diluted with 100 parts or 20 fl.ounces of Water, stirring constantly. Wash the precipitate as directed, page 44, until the washings show only a slight cloudiness with test-solution of chloride of barium, then drain it, transfer to a capacious weighed porcelain dish and add the Nitric Acid, stirring until a clear solution is obtained. Finally, add enough Distilled Water to make 100 parts or 2 ounces av. The Br. Liquor Ferri Pernitratis, or Solution of Pernitrate of Iron, is made by dissolving 1 ounce av. of Iron Wire in 4^ fl.ounces of Nitric Acid, diluted with 16 fl.ounces of Water, filtering the solution and adding enough water to make 30 fl.ounces (Imperial). Uses. — This solution is given in doses of 5 to 30 minims as a tonic and astringent. LIQUORES — SOLUTIONS. 557 1887. Liquor Ferri Oxychlorati. G. P. Solution of Oxychloride of Iron. This Solution is official in the G. P. Solution of Chloride of Iron (G. P.) 35 parts. Water of Ammonia 35 parts. Hydrochloric Acid, 3 parts. Water, a sufficient quantity. Mix 160 parts of Water with the Solution of Chloride of Iron and add it, with constant stirring, to the Water of Ammonia, mixed with 320 parts of Water ; wash the precipitate as directed, page 44, and having drained and pressed it, mix it with the Hydrochloric Acid and set aside for three days ; then add enough water to bring the specific gravity of the product to 1.050. This liquid contains 3.5 per cent, of Iron. It may be used in place of Solu- tion of Dialvsed Iron. 1888. Liquor Ferri Subsulphatis. Solution of Subsulphate of Iron — Solution of Basic Ferric Sulphate — Monsel's Solution. The U. S. formula is: Sulphate of Iron, 77 parts or 13 ounces av. Sulphuric Acid, 7 parts or 510 grains. > each sufficient to make 1 14 parts or to ounces av. Distilled Water, S Mix the Sulphuric Acid with n parts or 800 grains of Nitric Acid, and 50 parts or 8 fl. ounces of Distilled Waiter, in a capacious porcelain capsule, and having heated the mixture to the boiling point add the Sulphate of Iron (one fourth at a time), stirring after each addition until effervescence ceases. Should the addition of a few drops of Nitric Acid cause a further evolution of red fumes, cautiously add Nitric Acid until red fumes cease to be evolved. Then keep the solution in brisk ebullition until nitrous vapors are no longer perceptible and the liquid assumes a deep ruby-red tint. Lastly, add enough Distilled Water to make the solution weigh 114 parts or 19 ounces av. It contains 48. 7 per cent, of Basic ferric Sulphate Fe 4 0(S0 4 ) 6 . Sp.gr. 1.55. 'I he Br. Liquor Ferri Persulphatis, or Solution of Persulphate of Iron, is similar to this, and when .Solution of Persulphate of Iron is prescribed or ! this should be 1 ed. It contains less acid than the Solution of ! ulphate of Iron, and is much stronger of the iron salt. Uses.— This solution is used as a styptic application for stopping hemor- tnd is given internally in doses of 3 to 6 minims, diluted with water;, as .in astringent. 558 LIQUORES — SOLUTIONS. 1889. Liquor Feiri Tersulphatis. Solution of Tcr sulphate of Iron — Solution of Normal Ferric Sulphate. Sulphate of Iron, 80 parts or 8 ounces av. Sulphuric Acid, 15 pans or \y z ounces av. Niiric Acid, ) each a sufficient quantity to make \ 2Q ounces av Distilled Water, ) 200 parts or i Mix the Sulphuric Acid with n parts or 482 grains of Nitric Acid and with 50 parts or 5 fl. ounces of Distilled Water, and proceed as directed in the foregoing formula, adding enough Distilled Water at last to make 200 parts or 20 ounces av. This solution contains 28.7 per cent of Normal Ferric Sul- phate, Fe 2 (S0 4 ) 3 . Its sp. gr. is 1.32. Uses.— In pharmacy this solution is used in making many other iron prep- arations, Ferric Hydrate being precipitated from it with Ammonia. For medicinal use the Solution of Subsulphate of Iron is preferred. 1890. Liquor Gutta-Perchae. Solution of Gutta-Percha. The U. S. formula is — Gutta-Percha in thin slices 9 parts. Commercial Chloroform, by weight, 91 parts. Carbonate of Lead 10 parts. Add the Gutta-Percha to 70 parts of the Chloroform contained in a bottle, cork it well, and shake it occasionally until the Gutta-Percha is dissolved. Then add the Carbonate of Lead previously mixed with the remainder of the Chloroform, and having several times shaken the whole together at intervals of half an hour, set the mixture aside until the insoluble matters have sub- sided and the solution has become perfectly clear. Lastly, decant the liquid and preserve it in small cork-stoppered vials. The Br. formula is about the same. Gutta-Percha in thin slices 1 ounce, Chloroform 8 fl ounces, Carbonate of Lead in tine powder 1 ounce. It is made in the same way. Uses.— This soluron is used in pharmacy for mixing with mustard to make mustard paper, and may be used for other adhesive purposes, and as a cement or glue for rubber, etc. 1891. Liquor Hydrargyri Nitratis. Solution of Nitrate of Mercury — Solution of Mercuric Nitrate. The U. S. formula is : Red Oxide of Mercury, 60 parts or 4 ounces av. Nitric Acid 45 parts or 3 flounces. Distilled Water 1 5 parts or 1 K flounces. LIQUORES — SOLUTIONS. 559 Mix the Nitric Acid with the Water and dissolve the Red Oxide of Mer- cury in the mixture. Keep the solution in glass-stoppered bottles. This solution contains about 50 per cent, of Mercuric Nitrate Hg (N 3 ) 2 . The solution of Nitrate of Mercury, formerly official, was similar to the Br., which is now called Liquor Hydrargyri Nitratis Acidus, or Acid Solu- tion of Nitrate of Mercury, and is made by dissolving with the aid of gentle heat 4 ounces av. of Mercury in 5 fi.ounces of Nitric Acid mixed with i]/ 2 fi.ounces of Distilled Water. Uses. — This solution is used as a caustic application for ulcers, cancers, and malignant sores. 1892. Liquor Hydrargyri Perchloridi. Br. Solution of Per chloride of Mercury. This is official in the Br. P., made as follows : Perchloride of Mercury (Corrosive Sublimate). ... 10 grains. Chloride of Ammonium 10 grains. Distilled Water (Imperial measure; 20 fi.ounces. Dissolve. The dose is y 2 fl. drachm to 2 fl. drachms. 1893. Liquor Iodi Compositus. Compound Solution of Iodine — ■ Lugol's Solution. The U. S. formula is : Iodine 5 parts or yi ounce av. Iodide of Potassium io parts or 1 ounce av. Distilled Water, 85 parts or 8}i fi.ounces. live the Iodine and Iodide of Potassium in the Distilled Water, and keep the solution in wcll-stopoed bottles. The P>r. P. under the heading Liquor Iodi or Solution of Iodine directs 10 parts, Iodide of Potassium 15 parts, Distilled Water 200 parts. The percentage of Iodine is the same as in the U. S. formula. Uses.— Lugol's Solution, as it is popularly known is given internally in if 3 to 5 minims diluted with water, as an alterative and absorbent. The following are well-known similar unofficial solutions of Iodine Compound : 1894. Churchill's Iodine Caustic— Iodine 60 grains, Iodide of Potassium 120 grains, Water 4 fl.drachms. For external use. 1895. Magendie's Iodine Solution. — Iodine 2 grains, Iodide of Potassium 24'« grains, Peppermint Water 6 fi.ounces. Dose, a teaspoonful or more. 560 LIQUORES — SOLUTIONS. 1896. Liquor Kalii Acetici. G. P. Solution of Acetate of Potassium. Acetic Acid (G. P.) 100 parts. Bicarbonate of Potassium 48 parts. Water, sufficient to make 147 parts. Add the Bicarbonate of Potassium gradually to the Acetic Acid, and heat the Solution to boiling ; then neutralize with Bicarbonate of Potassium and add sufficient Water to make 147 parts. Three parts of the Solution contain one part of the dry salt. 1897. Liquor Kalii Carbonici. G. P. Solution of Carbonate of Potassium. Pure Carbonate of Potassium 11 parts. Water 20 parts. Dissolve the salt in the Water, and filter the Solution. Three parts of the Solution contain one part of the dry salt. 1898. Liquor Lithiae Effervescens. Br. Effervescing Solution of Lit/iia — Lithia Water. This is made by adding 10 grains of Carbonate of Lithium to 20 fl.ounces of Water and charging with Carbonic Acid Gas to about 60 pounds pressure, in strong glass bottles. It is used for kidney diseases. The dose is 5 to 10 fl.ounces. 1899. Liquor Magnesii Carbonatis. Br. Solution of Carbonate of Magnesium — Fluid Magnesia. Sulphate of Magnesium (Epsom Salt) 2 ounces av. Carbonate of Sodium (Sal Soda) 1%. ounces av. Distilled Water, a sufficiency. Dissolve the Salts separately each in half a pint of water. Heat the Solution of Sulphate of Magnesium to the boiling point and add to it the Solu- tion of Carbonate of Sodium and boil them together until Carbonic Add ceases to be evolved. Wash the precipitate as directed, page 44, until the washings cease to give a precipitate with test solution of Chloride of Barium. Mix the precipitate with 20 fl.ounces of Distilled Water and charge with Carbonic Acid Gas to about 50 pounds pressure. Let stand under pressure for 24 hours, then filter to remove any undissolved Carbonate of Magnesium and charge again with gas in bottles. This solution contains about 2 per cent, of Magnesia. The dose is 1 to 2 fl.ounces. Fluid Magnesia is a popular remedy in Great Britain, but is little used in this country. LIQUORES — SOLUTIONS. 561 1900. Liquor Magnesii Citratis. Solution of Citrate of Magtiesium. Carbonate of Magnesium 200 grains. Citric Acid, 400 grains. Syrup of Citric Acid, 2 fl. ounces.- Bicarbonate of Potassium 30 grains. Water, a sufficient quantity. Dissolve the Citric Acid in 4 fl. ounces of Water, and, having added the Carbonate of Magnesium, stir occasionally until it is dissolved. Filter the solution into a strong bottle of 12 fl. ounces capacity, containing the Syrup of Citric Acid, then add, without agitation, Water previously boiled and filtered to nearly fill the bottle, and, lastly, add the Bicarbonate of Potassium in Crystals and immediately close the bottle with a good cork, which must be tied down with twine. The Br. formula directs l / z fl. ounce Syrup of Lemons instead of the Syrup of Citric Acid, and 40 grains instead of 30 grains of Bicarbonate of Potas- sium. Uses.— This solution is familiarly known as "Citrate of Magnesia," and is. used as a laxative and refrigerant, in doses of a bottle or less. 1901. Permanent Solution Citrate of Magnesium. As made by the foregoing formula this solution soon decomposes and becomes unfit for use. The following is proposed as an unalterable solution that will keep indefinitely : Boric Acid 1 ounce av. Citric Acid 6 ounces av. Carbonate of Magnesium y/ 2 ounces av. Distilled Water 40 ll.ounces. Dissolve the Boric Acid in 20 flounces of hot water, add the Citric Acid and the remainder of the water. When cool add the Carbonate of Magnesium, dissolve and filter the solution. To 8 fl.ounces of this solution in a 12-ounce bottle add 2 ounces Syrup Citric Acid and 30 grains Bicarbonate of Potas- sium. Cork and tic down in the usual manner. 1902. Liquor Morphinae Acetatis. Br. Solution of Acetate of Morphine. Ai etate of Morphine 9 grains or 1 part. Diluted Arctic Acid, iS minims or 2 fl.parts. Rectified Spirit # fl.ounce or 24 11. parts. Distilled Water [# fl.ounces or 73 fl.parts. Mix the Acid, the Spirit and the Water and dissolve the Acetate of Mor- phine iu the solution. The solution contains 1 per cent, of the. Salt. The dose is 10 to 60 minims. 562 LIQUORES — SOLUTIONS. 1903. Liquor Morphinae Bimeconatis. Br. Solution of Bimeconate of Morphine. Hydrochlorate of Morphine 9 grains. Solution (Water) of Ammonia, a sufficiency. Meconic Acid, 6 grains. Rectified Spirit, ]/ z flounce. Distilled Water, a sufficiency. Dissolve the Morphine salt in two or three drachms of Distilled Water, by the aid of heat, then add the solution of Ammonia until Morphine ceases to be precipitated. Cool, filter, wash the precipitate with distilled water until the washings cease to give a precipitate with Nitrate of Silver. Drain, mix the precipitate with sufficient water to produce an ounce and a half, add the Rectified Spirit and the Meconic Acid, and dissolve. This solution may also be made by dissolving 5^ grains of Bimeconate of Morphine in water 5 ti. drachms mixed with Alcohol 3 fl.drachms. ft is about the same strength as Tincture of Opium. Uses. — This solution is considerably used in place of Tincture of Opium in doses of 5 to 40 minims. 1904. Liquor Morphinae Hydrochloratis. Br. Solution of Hydrochlorate of Morphine. Hydrochlorate of Morphine, ... 9 grains or 1 part. Diluted Hydrochloric Acid, ... 18 minims or 2 fl.parts. Rectified Spirit, y 2 flounce or 24 fl.parts. Distilled Water, 1%. flounce or 73 fl.parts. Mix the Hydrochloric Acid, the spirit and the water and dissolve the Morphine salt in the mixture. It contains 1 per cent, of the Morphine salt. The dose is 10 to 60 minims. 1905. Liquor Morphinae Sulphatis. Solution of Sulphate of Morphine. Although this solution is not now official it is more frequently prescribed in this country than any of the foregoing solutions of Morphine. The formula of the 1870 U. S. P. was : Sulphate of Morphine 8 grains. Distilled Water 8 flounces. Dissolve the Morphine salt in the Water. Dose, yi grain. Elixir Mor- phine (697) is preferable to this solution, and of the same strength. Magendies Solution of Morphine is made with Sulphate of Morphine 8 grains, Distilled Water 1 flounce. This should never be dispensed unless it is definitely prescribed or directed. LIQUORES — SOLUTIONS. 563 1906. Liquor Pepsini. U. S. Solution of Pepsin — Liquid Pepsin. Saccharated Pepsin 40 parts or 300 grains. Hydrochloric Acid 12 parts or 66 minims. Glycerin 400 parts or 5 fl. ounces. Water, 548 parts or 8 fl.ounces. Dissolve the Saccharated Pepsin in the Water previously mixed with the Hydrochloric Acid, add the Glycerin, let the mixture stand 24 hours, and filter or strain. Uses.— Solution of Pepsin is given as an aid to digestion in doses of 2 to 4 11. drachms, or more. 1907. Solution of Lactopeptine or Liquid Lactopepti?ie may be made in the same proportions and manner as the above. Lactic Acid may be used instead of Hydrochloric Acid. Liquor Pancrco-Pepsin may be made by macerating Saccharated Pepsin 256 grains, Saccharated Pancreatin 128 grains, in a mixture of Hydrochloric Acid 90 minims, Lactic Acid 60 minims, Glycerin 5 fl.ounces, Water 1 1 fl.ounces ; then filter. This is similar to Solution of Lactopeptine. 1908. Liquor Plumbi Subacetatis. Solution of Subacetate of Lead — Goulard's Extract. The U. S. formula is : Acetate of Lead 170 parts* or 1900 grains. Oxide of Lead (Litharge) 120 parts or 1242 grains. Distilled Water, sufficient to make, . 1000 parts or 10 fl.ounces. Dissolve the Acetate of Lead in 800 parts or 10 fl.ounces of boiling Distilled Water in a glass or porcelain vessel. Then add the Oxide of Lead and boil for half an hour, adding a little Distilled Water from time to time to make up for the evaporation. Remove the heat, allow the liquid to cool, and add enough Distilled Water previously boiled to make 1000 parts or 10 tl. ounces and finally filter. Sp. gr. 1.228. The Br. P. directs Acetate of Lead 5 ounces av., Oxide of Lead 5^ ounces av., Distilled Water sufficient to make 20 fl.ounces (Imperial measure), to be made in the same manner as the foregoing. Sp. gr., 1.275. The German official preparation is made with Acetate of Lead 3 parts, Oxide of Lead r part, Distilled Water 10 parts, by melting the lead salts with one-twentieth part of the water on a water-bath and continuing the heat until the yellowish color of the mixture has changed to a white or reddish white, then adding the remainder of the water, setting aside and filtering. Sp.gr. 1.235. Uses.— This solution is used in Pharmacy for making cerate and liniment of Subacetate of Lead, and in medicine as an astringent and sedative application to inflamed surfaces, for injections, etc. It is generally diluted before using. 564 LIQUORES — SOLUTIONS. 1909. Liquor Plumbi Subacetatis Dilutus. Diluted Solution of Subacetate of Lead — Lead Water. This is the foregoing solution diluted, the U. S. formula being: Solution of Subacetate of Lead, ... 3 parts or 2 fl. drachms. Distilled Water 97 parts or 10 flounces. Mix the solution with the water previously boiled and cooled. The Br. P. directs Solution of Subacetate of Lead 2 fl.drachms, Rectified Spirit 2 fl.drachms, Distilled Water 19^ flounces, (Imperial measure) mak- ing a preparation only half the strength of the U. S. Uses.— This is used as a soothing application, etc., the same as the foregoing. 1910. Liquor Potassae. Solid ioti of Potassa. The U. S. formula is : Bicarbonate of Potassium, .... 90 parts or 2 ]/ 2 ounces av. Lime 40 parts or 1 ounce av. Distilled Water, sufficient to make, . 1000 parts or 24 fl. ounces. Dissolve the Bicarbonate of Potassium in 400 parts or 10 flounces of Distilled Water, heat the solution until effervescense ceases and then raise it to boiling. Slake the Lime, make it into a smooth paste with 400 parts or 10 fl. ounces of Distilled Water and heat to boiling, then gradually add the first liquid to the second and continue the boiling for 10 minutes. Remove the heat, cover tightly, and when cold add enough Distilled Water to make 1000 parts or 1% pints. Lastly, strain through linen, set the liquid aside until it is clear, and decant. Simple Process. — This may also be made by dissolving 1 ounce av. of Potassa (Caustic Potash) in a pint of Distilled Water; this is the method most generally employed by druggists. The U. S. preparation contains about 5 per cent, of Hydrate of Potassium. The Br. formula is Carbonate of Potassium 1 pound av., Slaked Lime 12 ounces av., Distilled Water 1 gallon (Imperial measure). The solution is made in a similar manner to the U. S., and contains 5.84 per cent, of the hydrate. The German Liquor Kail Canst lei, contains nearly 1 5 per cent, of the hydrate and must not be used when the U. S. or Br. solutions are intended. Uses.— In pharmacy Solution of Potassa is frequently used to saponify balsams or oils in mixtures, and in medicine is given largely diluted as an alkali or antacid. LIQUORES — SOLUTIONS. 565 1911. Liquor Potassii Arsenitis. Solution of Arsenite of Potassium — Fowler's Solution. Arsenious Acid in small pieces, ... 1 part or 74 grains. Bicarbonate of Potassium 1 part or 74 grains. Compound Tincture of Lavender, . . 3 parts or 2 fl. drachms. Distilled Water sufficient to make . . 100 parts or 1 pint. Boil the Arsenious Acid and Bicarbonate of Potassium in a glass vessel with 10 parts or \ l / z fl. ounce of Distilled water until the acid is completely dissolved. Then add the Compound Tincture of Lavender and enough Distilled Water to make 100 parts Or 1 pint; set the mixture aside for 8 days and filter through paper. 1912. Liquor Potassii Citratis. U. S. Citric Acid 6 parts or 480 grains. Bicarbonate of Potassium 8 parts or 640 grains. Water, a sufficient quantity. Dissolve the Acid and Potassium salt, each separately in 40 parts or about 6 fl.ounces of Water. Filter the solutions and wash the filters with enough water to make 50 parts or 8 tl. ounces of each. Then mix them together and when effervescense has ceased, bottle. It should be freshly made when wanted for use. Concentrated solutions of these salts, made double the strength of the above, may be made and kept on hand for making this solution. Then for each fl. ounce of the solution required mix 2 fl. drachms of each solution with enough Water to make 1 flounce. Uses. — This solution is used as a cooling draught and diaphoretic in doses of 1 nr 2 teaspoonfuls mixed with water. A strong solution of Citrate of Potassium is also made for combining with elixirs, etc. (1926). 1913. Liquor Potassae Effervescens. Br. Effervescing Sola lion of Potash — Potash Water. Bicarbonate of Potassium 30 grains. Water 20 fl.ounces. Dissolve the Salt in the Water and charge with Carbonic Acid ('.as to about 60 pounds pressure, then bottle under pressure. Uses.— This is given in doses of 2 to 4 11. ounces as an antacid or alkaline draught. 566 LIQUORES — SOLUTIONS. 1914. Liquor Potassii Permanganatis. Br. Solution of Permanganate of Potassium. Permanganate of Potassium, 88 grains. Distilled Water (Imperial measure) 20 fl. ounces. Dissolve. This solution was official in the 1870 U. S. P. ; 4 grains of the salt being dissolved in 1 fl. ounce of water. Uses.— It is given in doses of 2 to 4 fl. drachms for foul stomach, bad breath, etc. ; also used externally as a wash for sores, ulcers, etc. 1915. Liquor Sodas. Solution of Soda. The U. S. formula is : Carbonate of Sodium, 180 parts or 5 ounces av. Lime 60 parts or 1 l / 2 ounces av. Distilled Water sufficient to make . 1000 parts or 24 flounces. Dissolve the Carbonate of Sodium in 400 parts or 10 fl. ounces of boiling Distilled Water. Slake the Lime and make it into a smooth mixture with 400 parts or 10 fl. ounces of Distilled Water and heat to boiling. Then graduallv add the first liquid to the second and continue the boiling for 10 minutes. Remove the heat, cover the vessel tightly, and when cold add enough Distilled Water to make 1000 parts or \)A pints. Lastly, strain through linen, set the liquid aside until clear, and decant. Simple Process. — This may also be made by dissolving 1 ounce av. of Soda (Caustic Soda) in a pint of Distilled Water, and this method is generally employed by druggists. The U. S. preparation contains about 5 percent, of Sodium Hydrate. The Br. formula is Carbonate of Sodium 28 ounces, Slaked Lime 12 ounces, Distilled Water 1 gallon (Imperial measure). The solution is made in a similar manner to the U.S. and contains a little more than 4 per cent, of Sodium Hydrate. The German Liquor Natri Caustici contains nearly 15 per cent, of the Hydrate and must not be used when the U. S. or Br. solutions are intended. Uses.— This solution is used for similar purposes and in the same doses as Solution of Potassa, the last named being generally preferred for medicinal uses. 1916. Liquor Sodae Chloratae. U. S. Solution of Chlorinated Soda — Liquor Soda Chlorinates. Br. The U. S. formula is : Carbonate of Sodium 100 parts or 25 ounces av. Chlorinated Lime, 80 parts or 20 ounces av. W ater sufficient to make 1000 parts or 14 pints. LIQUORES — SOLUTIONS. 567 Mix the Chlorinated Lime intimately with 400 parts or 5^ pints of Water in a tarred vessel provided with a closely fitting cover. Dissolve the Car- bonate of Sodium in 400 parts or $}4 pints of boiling Water, and immedi- ately pour the latter solution into the former; cover the vessel tightly, and when the contents are cold, add enough Water to make 1000 parts or 14 pints. Lastly, strain the mixture through muslin, allow the precipitate to subside and remove the clear solution by means of a siphon, or decant. The Br. formula is Carbonate of Sodium 24 ounces av., Chlorinated Lime 16 ounces av., Distilled Water 1 gallon (Imperial measure). It is made in a similar manner. The solution of Chlorinated Lime was formerly called Labarraque's Solution or Liquor of Chloride of Oxide of Soda. It differs from Eau de fa-velle (Javelle Water) in being prepared with Carbonate of Sodium instead of Carbonate of Potassium, but its uses are similar. Uses. — This solution is used as a deodorizer and disinfectant also for bleaching and removing fruit stains from linen, and is given as an antiseptic in doses of 10 to 20 minims ; also used as a gargle and for insufflating largely diluted with Water. 1917. Liquor Sodii Arseniatis. Solution of Arseniate of Sodium. Arseniate of Sodium, rendered anhy- drous by a temperature not exceeding 300 F. (148 9 C.j, 9 grains or 1 part. Distilled Water 2 fl. ounces or 99 fi. parts. Dissolve. Dose 5 to 10 minims. The Br. formula is the same. Uses.— This solution is used for the same purposes as Fowler's Solution. It contains 1 per cent, of the Arsenic salt. 1918. Liquor Sodii Ethylatis. Br. Solution of Ethylate of Sodium. Metallic Sodium, free from Oxide, 22 grains. Ethylic (Common) Alcohol 1 il. ounce. Dissolve the Sodium in the Alcohol contained in a Mask, the latter being kept cool in a stream of cold water. The solution should be recently prepared. 1019. Liquor Sodii Silicatis. Solution oj Silicate of Sodium Liquid Glass— Water Glass. This may be made by mixing one part of line sand and two parts of dried Carbonate of Sodium together and fusing them in an earthenware crucible, 568 LIQUORES — SOLUTIONS. pouring out the fused mass on a slab, and, when cool, powdering it and dissolving its soluble portion in water by the aid of heat ; the clear liquid being decanted and reduced to a liquid of the consistence of thick syrup by evaporation. It contains about 30 per cent, of the salt. Uses. — This solution is known commercially as Liquid Glass, and is used in making cements, kalsomine preparations, plaster compositions, wood filling, and many other like purposes. It is frequently added to cheap soaps to increase their weight and make them absorb more water. In surgery, it is used in preparing mechanical dressings ; and in dentistry, for mixing with plaster for casts, making cements, etc. 1920. Liquor Strychninae Hydrochloratis. Br. Solution of Hydrochlorate of Strychnine — Liquor Strychninae. Strychine in Crystals 9 grains or 1 part. Diluted Hydrochloric Acid 14 minims or 2 fl. parts. Rectified Spirit ]/ 2 flounce or 24 fl. parts. Distilled Water \ l / 2 fl. ounce or 73 fl. parts. Mix the Acid with 4 drachms of the Water and dissolve the Strychnine in the mixture by the aid of heat ; then add the Spirit and remainder of the Water. This solution contains 1 per cent, of Strychnine and may be given in doses of 5 to 10 minims. 1921. Liquor Zinci Chloridi. Solution of Chloride of Zi>ic. The U. S. formula is : Zinc, Granulated 240 parts or 6% ounces av. Nitric Acid 12 parts or 100 minims. Precipitated Carbonate of Zinc, . . 12 parts or 136 grains. Hydrochloric Acid, ) Distilled Water, . \ each a suftlcient ^ uantit ^ To the Zinc contained in a glass or porcelain vessel, add, gradually, enough Hydrochloric Acid to dissolve it; then strain the solution, add the Nitric Acid, evaporate to dryness, and bring the dry mass to fusion. Let it cool, dissolve it in 150 parts or 4}4 flounces of Distilled Water, add the precipi- tated Carbonate of Zinc and agitate the mixture occasionally during 24 hours. Finally, filter through white filtering paper free from iron and pass enough Distilled Water through the filter to make 1000 parts or 1 pint of the solu- tion, which contains about 50 per cent, of Chloride of Zinc. The Br. formula is Granulated Zinc 1 pound av., Hydrochloric Acid 44 fl. ounces, Solution of Chlorine ("Chlorine Water") a sufficiency, Carbonate of LIQUORES — SOLUTIONS. 569 Zinc, l />. ounce, or a sufficiency, Distilled Water 20 rl. ounces ; to be made into 2 pints (Imperial measure) of solution. Solution of Chloride of Zinc may also be conveniently made by dissolving 1 ounce av. of granular Chloride of Zinc in 1 rl. ounce of Distilled Water. This is the method usually employed by druggists. A common cheap solution of Chloride of Zinc for disinfecting may be made by dissolving Zinc in strips or cuttings in commercial Hydrochloric Acid to saturation. Uses. — This solution is used mainly as a disinfectant and antiseptic. Embalming Fluids are chiefly diluted solutions of Chloride of Zinc. Unofficial Solutions. USED FOR COMBINING WITH ELIXIRS, SYRUPS, ETC. The preparations included under this heading are mostly- strong solutions of chemical salts, convenient for combining with elixirs, emulsions, syrups, etc. A few, however, are intended to be used or prescribed as they are. Several other solutions useful for similar purposes will be found under other headings, as coloring solutions, dialysates, official solutions, etc. These arc the solutions which are referred to in the various elixirs, emulsions, syrups, etc., when it is noted that " an equivalent quantity of the solution of the specified salt may be used." They are given more prominence in this work than the official solutions, because of their use as described. 1922. Solution of Carbolic Acid. Although a standard solution of Carbolic Acid is not official, sucli a preparation is furnished by manufacturers and by com- mon consent is made to contain 5 grains of Carbolic Acid in each tl. drachm. It may be made as follows: Carbolic Acid (Crystals) 640 grains. ( rlycerin, } , cc ■ , , -.. each, a sufficient quantity. Water. * Liquefy the Acid by the aid of heat and add 2 ounces of Glycerin to the solution, then add enough Wain- to make the measure \ \ fl.ounces. If the solution is then clear add enough 570 LIOUORES — SOLUTIONS. Water to make 16 fl. ounces, but if it should be " milky " add enough Glycerin to make clear, and then sufficient water to make the measure a pint, and filter. Solutions of Carbolic Acid of other strengths may be made in the same manner. See, also, Nos. 29 and 1750. 1923. Solution Chloride of Iron. (Tasteless.) TASTELESS TINCTURE CHLORIDE OF IRON. Solution Chloride of Iron (1883), • • 4 A. ounces. Carbonate of Sodium 10 ounces av. Citric Acid, 6 ounces av. Water, q. s. to make, 1 pint. Dissolve the Citric Acid in 4 fl. ounces of boiling Water and add the Carbonate of Sodium, in crystals, gradually until all is added and effervescense has ceased ; then add the Solution of Chloride of Iron and enough Water to make a pint of the solution. This is a Solution of Citro-Chloride of Iron and Sodium. It may also be made by dissolving 6 ounces av. of Citrate of Potassium or Citrate of Sodium in half a pint of Water and adding the Solution of Iron and then enough Water to make the measure a pint. Uses. — This solution is the same strength of Chloride of Iron as the official Tincture Chloride of Iron, and may be used for the same purposes and in the same dose. It is somewhat acid, but the styptic taste of the Iron is avoided. It is used in making several elixirs and syrups, as Elixir Gentian with Tincture Chloride of Iron, etc., and is employed in the same quantity as the official tincture. 1924. Solution Citrate of Bismuth and Ammonium. For combining with elixirs, etc., a strong solution of Citrate of Bismuth and Ammonium is desirable to use instead of the salt, as an equivalent quantity may be added to any prepara- LIQUORES — SOLUTIONS. 571 tion and thus save the time and trouble of dissolving the salt. It may be made as follows : Citrate of Bismuth and Ammonium, . 8 J 3 ounces av. Water of Ammonia, q. s., about, . . I )A fl. ounce. Warm Water, sufficient to make, . . i pint. To S ounces of Warm Water contained in a mortar add the Bismuth Salt in small portions at a time and Water of Ammonia a little at a time, rubbing them well together until the salt is all dissolved, taking care that Ammonia shall not be in excess enough for its odor to be noticeable, then add sufficient water to make a pint, and filter or decant. This solution contains 50 per cent, of the Bismuth Salt, therefore, in using it in elixirs, etc., where Citrate of Bismuth and Ammonium is directed, twice the quantity stated of the salt, or 2 minims for each grain should be used. 1925. Solution of Citrate of Iron and Ammonium. Citrate of Iron and Ammonium, . . 8^-3 ounces aw Water, sufficient to make, . . . . 1 pint. Dissolve the Iron Salt in half a pint of hot water, and when cool add enough water to make a pint. This is a 50 per cent, solution convenient for using in elixirs, syrups, etc., when the scale salt is directed. Use 2 minims for each grain of the salt directed in the formula. Solution of Citrate of Iron (1884) may be used in many preparations instead of this, but is not so readily held in solution. 1926. Solution Citrate of Potassium. Carbonate of Potassium 8 ounces av. Citric Acid 6 ounces aw Water, sufficient to make 20 fl.ounces. I': iolve the Carbonate of Potassium in io fl.ounces of Water and add the ' it in Arid a little at a time When all has LIQUORES — SOLUTIONS. been added and effervescense ceases, add enough Water to make 20 fl. ounces of the solution and filter. Use double the quantity of this solution as is directed of the salt in the formula. 1927. Solution of Citric Acid. A convenient Solution of Citric Acid for combining may be made as follows : Citric Acid 8^3 ounces av. Water, sufficient to make . . . . 1 pint. Dissolve the Acid in half a pint of hot water and when cool make up the measure with water to a pint. This is a 50 per cent, solution and will keep without change. Use 2 minims of this solution for each grain of Citric Acid directed in the formula. 1928. Solution Hypophosphite of Iron. Solution Phosphate of Iron (1936), . . 2 fl. ounces. Hypophosphorus Acid, diluted (34), . . 1 fl. ounce. Glycerin, 1 fl. ounce. Mix them. Although this is not, chemically, a true solution of Hypo- phosphite of Iron, it is, in effect, the same for all pharmaceu- tical and medicinal use, and is readily made and permanent. Four minims of this Solution represents one grain of the Iron salt. 1929. Solution Hypophosphite of Manganese. Hypophosphite of Manganese, . . . 480 grains. Hypophosphorus Acid, diluted (34), . 3 fl. ounces. Water, sufficient to make 4 fl. ounces. Dissolve the Manganese salt in the Acid by the aid of gentle heat and add Water sufficient to make the measure 4 fl. ounces. Four minims of this solution represents one grain of the Manganese salt. LIQUORES — SOLUTIONS. 573 1930. Solution of Hypophosphites Compound. Hypophosphite of Calcium, .... 256 grains. Hypophosphite of Sodium, . . Hypophosphite of Potassium, . Hypophosphite of Iron Solution, Hypophosphorous Acid, diluted, Water, sufficient to make . . . 128 grains. 64 grains. 4 fl. drachms. 4 fl. drachms. 1 pint. Rub the Hypophosphite salts to a fine powder and then with Water in portions of 4 ounces each until they are dis- solved ; add the Solution and Acid, and filter. This Solution is not intended to combine with other prepara- tions but to be used as it is. It is similar to a preparation which was once extensively sold as a proprietary medicine, as " CJmrcJiiirs Solution of Hypophosphites Compound," but it has been mostly superseded by various syrups of Hypophosphites. A fl. drachm contains about 4 grains of Hypophosphites. The dose is a teaspoonful to a dessertspoonful. 1931. Solution Lactophosphate of Cal- cium (Lime). Solution Phosphate of Calcium (1935), . 8 fl. ounces. Concentrated Lactic Acid, 1 fl. ounce. Evaporate the Solution of Phosphate of Calcium by the heat of a water-bath to 7 fl. ounces, and when cool add the ntrated Lactic Acid. This Solution may also be made by dissolving 1 ounce of Soluble Lactophosphate of Lime in sufficient Water to make 4 fl. ounces. Four minims of this Solution represents one grain of Lacto- phosphal e of < 'alcium. 1932. Solution Lactophosphate of Iron. Solution Phosphate of Iron 2 fl. ounces. Glycerin 1 fl.ounce. Concentrated Lactic Acid 1 fl.ounce. Mix them. 574 LIQUORES — SOLUTIONS. Four minims of this Solution represents one grain of the Iron salt. It is not, strictly speaking, a Solution of Lacto- phosphate of Iron but of the Compound Phosphate of Iron with Lactic Acid. It is conveniently made and may be used for all pharmaceutical and medicinal purposes, where Lacto- phosphatc of Iron is desired in solution. 1933. Lactophosphate of Manganese. Solution Phosphate of Manganese, . . 8 fl. ounces. Concentrated Lactic Acid, 1 fl. ounce. Evaporate the Solution of Phosphate of Manganese by the heat of a water-bath to 7 fl. ounces, and when cool add the Lactic Acid. Four minims of this Solution represents one grain of Lac- tophosphate of Manganese. 1934. Solution of Lactophosphates Compound. Solution Lactophosphate of Calcium, . 2 fl. ounces. Solution Lactophosphate of Iron, . . 1 fl. ounce. Mix them. This solution may be used in making some elixirs, syrups, etc., or may be diluted with 10 parts of Water and employed as a medicine, in doses of a teaspoonful or more. Four minims of the Solution represents one grain of the Lactophosphates combined in the proportion of ^3 g r - Lacto- phosphate of Calcium and ^ gr. Lactophosphate of Iron. I 935- Solution Phosphate of Calcium (Lime). Precipitated Phosphate of Calcium, . . 2 ounces av. Phosphoric Acid, 50 per cent. (U. S. 1880), 6 fl. ounces. Distilled Water, a sufficient quantity. Put the Phosphoric Acid in a porcelain evaporating dish and add the Phosphate of Calcium in small portions, stirring it well with the Acid. When all is added heat moderately by a water-bath, stirring occasionally for several hours, then heat LIQUORES — SOLUTIONS. 575 on a sand-bath to about 240 F., stirring occasionally for sev- eral hours, until the liquid is reduced to a granular crystalline mass. Allow this to cool, and add sufficient distilled Water that when dissolved the liquid shall measure 10 fl. ounces, and filter. As this is a saturated Solution it may happen that it will solidify or become gelatinous, but it is only necessary to add to it a small quantity of Water and dissolve by the heat of a water-bath before using. Four minims of this Solution represents about one grain of the Salt, which, in this Solution, is converted from the Phos- phate into the Biphosphate of Calcium. This Solution is used for making several elixirs, syrups, etc., and as the basis of Solution Lactophosphate of Calcium. A soluble salt, Biphosphate of Calcium, may be prepared by con- centrating this Solution and crystallizing. A Solution of Phosphate of Lime or Calcium has formerly been prepared by dissolving precipitated Phosphate of Calcium in sufficient Hydrochloric Acid, diluted with Water, filtering the solution, precipitating it with Ammo- nia or Solutions of the Alkaline Carbonates, washing the precipitate, draining and pressing it, and dissolving it in Phosphoric Acid, but it is believed the method as above described will be more satisfactory. 1936. Solution Phosphate of Iron. Phosphate of Iron, in scales (1880), . 4^3 ounces av. Glycerin, 2 fl. ounces. Water, sufficient to make 8 fl. ounces. Heat 6 fl. ounces of Water to boiling in an evaporating dish and add the Iron salt in small portions at a time, stirring constantly, and continuing the heat until all has been added and dissolved, then add the Glycerin and evaporate the liquid carefully until it measures 8 fl. ounces. This solution contains 50 per cent, of the Iron Salt. Two minims of this solution contains 1 grain of the Iron Salt, therefore double the quantity of minims as is directed of grains in the formulas may be used. It is very convenient to keep prepared in this form for general dispensing purposes, as well as for making Elixirs, Syrups, etc. A solution of Phosphate of lion was formerly made by precipitating a solution of Phosphate of Sodium with a solution of Sulphate of Iron, 576 I.F< >UORES — SOLUTIONS. washing- the precipitate, draining and pressing it and dissolving it in Phos- phoric Acid, using the same proportions and method as is directed for making solution Phosphate of Manganese; but the introduction of the Scale Salt Phosphate of Iron gives us a much better preparation, made with much less trouble. 1937. Solution Phosphate of Manganese. Sulphate of Manganese, 5 ounces av. Phosphate of Sodium, 7 ounces av. Phosphoric Acid, 50 per cent., .... 8 fl. ounces. Sugar, 5 ounces av. Water, a sufficient quantity. Dissolve the Manganese and Sodium Salts separately, each in 4 pints of warm Water, and add the Solution of Sulphate of Manganese to the Solution of Phosphate of Sodium. Wash the precipitate as directed, page 44, collect, drain and press out the Water as much as possible, then dissolve the moist precipitate in the Phosphoric Acid, add the Sugar to the solution and sufficient Water to make the measure 20 fl. ounces and filter. Use 4 minims of this solution as an equivalent of 1 grain of the salt when directed in liquid prep- arations. 1938. Solution of Phosphates Compound, Concentrated. Solution Phosphate of Calcium, 12 fi. ounces. Solution Phosphate of Iron, ... 1 fl. ounce. Phosphate of Sodium 320 grains. Carbonate of Potassium, . . . .128 grains. Carbonate of Magnesium, . . . .128 grains. Phosphoric Acid, 50 per cent., . . I fl. ounce. Water, sufficient to make, .... 1 pint. Mix the solution of Phosphate of Calcium and Iron, add the Carbonate of Magnesium and Potassium to the Phos- phoric Acid, and when effervescense has ceased, add the Phos- phate of Sodium, in fine powder, and 1 ounce of warm Water. Mix the two solutions and add enough Water to make the measure a pint. LIQUORES — SOLUTIONS. 577 A fl. drachm of this solution contains about 12 grains Phos- phate of Calcium, 2 grains Phosphate of Iron, 2 x / 2 grains Phos- phate of Sodium, and 1 grain each Phosphate of Potassium and Magnesium, with excess of Phosphoric Acid. It is similar in composition to nearly all the Compound Elixirs, Syrups. and solutions of Phosphates Compound, and may be used for making them by diluting with Elixir, Syrup, Water or other liquids. It is also used for making "Acid Phosphate," and " Fruit Phosphates," for Soda Water, etc. A formula for this solution was published in The Formulary, August. 1885, of which the following is an abstract, but it is believed the foregoing will be more satisfactory : Phosphate of Calcium, 32 ounces, is dissolved in a sufficiency of Hydro- chloric Acid diluted with Water and the solution filtered ; this is precipitated with a sufficient quantity of stronger Water of Ammonia, and set aside. Carbonate of Sodium, 6 ounces, is dissolved in half a gallon of Water and Sulphate of Iron, 5 ounces, in half a gallon of Water, and the Iron solution added to the Sodium solution, precipitating Oxide of Iron. This mixture is then added to the reserved Calcium mixture, and the precipitate washed as directed, page 44, until free from chlorides and sulphates. The precipitate is then collected, drained and pressed, and while moist dissolved in 5 lbs. av. of Phosphoric Acid, 50 per cent. To this solution add Phosphate of Sodium 6 ounces, and Carbonate of Potassium 3 ounces, and Water sufficient to make 1 gallon. 1939. Solution of Phosphates Compound. " Acid Phosphate." Solution Phosphates Compound, concen- trated, 1 pint. Water, 4 pints. Mix them, and, after standing, filter. This solution is similar in composition to a popular proprie- tary preparation made by the Rumford Chemical Co. of Providence, R. I., and known as "Acid Phosphate." As the manufacturers claim this title as proprietary, druggists are not allowed to put it up or dispense it under this name. Solution of Phosphates Compound is considerably used at the Soda Water counter as an addition to beverages, etc., and is a popular nerve tonic and vitalizes 578 LIQUORES — SOLUTIONS. 1940. Solution " Protoxide" of Iron. A Solution of Protocitrate of Iron, which is the same as is generally furnished as " Protoxide " of Iron may be made as follows : Sulphate of Iron, pure crystals, ... 3 ounces av. Carbonate of Sodium 4 ounces av. Citric Acid, 2 ounces av. Sugar, 4 ounces av. Warm Water, a sufficient quantity. Dissolve the Iron Salt in half a gallon of warm Water, and the Sodium Salt in half a gallon of warm W r ater, and add the Iron solution to the Sodium solution. When the precipitate has subsided, wash as directed, page 44, until the washings are tasteless, then drain the precipitate quickly, press it, mix the Sugar with it and dissolve it in 8 fl. ounces of Water, in which the Citric Acid has previously been dissolved ; add enough Water if necessary to make the measure 16 fl. ounces, and filter. Four minims of this solution contains about I grain Pro- tocitrate of Iron. It is used in making several Elixirs, Syrups, Solutions, etc. 1941. Solution Pyrophosphate of Iron. Pyrophosphate of Iron 4^ ounces av. Glycerin, Water of Ammonia, 10 per cent. Water, sufficient to make . . In 8 fl. ounces of Water heated nearl the Pyrophosphate of Iron by adding it in small portions and stirring until dissolved, then, when cooling, add the Water of Ammonia and the Glycerin, and, lastly, sufficient Water to make the measure 1 pint. This solution is very convenient to use in place of the Salt, 4 minims being equivalent to I grain of Pyrophosphate of Iron. Since the introduction of the soluble Phosphate of Iron (scale salt), Pyrophosphate of Iron is much less used than formerly. 4 fl. ounces. ]/ 2 fl. ounce. 1 pint. y to boiling, dissolve LIQUORES — SOLUTIONS. 579 1942. Solution Sulphate of Strychnine. For combining with Elixirs, Syrups, Solutions, Wines, and like preparations, as well as for general dispensing, a Solution of Strychnine is a great convenience, if not a necessity. The following Solution is well adapted for this purpose : Sulphate of Strychnine, powdered, . . 32 grains. Citric Acid 8 grains. Alcohol, 2 fi. ounces. Water, sufficient to make 4 fi. ounces. Dissolve the Citric Acid in 2 fi. ounces of hot Water and add the Strychnine salt ; when nearly cool add the Alcohol and then sufficient Water to make the measure 4 fl. ounces. A fl. drachm of this Solution contains 1 grain Sulphate of Strychnine, therefore a fi. drachm may be used for each grain of Strychnine directed in the formulae. Caution. — This solution must only be used for combining with preparations or dispensing in place of Strychnine directed in liquid preparations. Several other Solutions of Strychnine, as Hall's (2038), containing only 1 grain in a fi. ounce, or the Br. Liquor Strychnine (1920), containing 1 part in 100, are known, and care must be exercised that this Solution is not used instead of them. Test-Solutions. The Pharmacopoeias designate and give formulas for a vari- ety of Solutions of chemical reagents which are used for test- ing the various substances mentioned in their pages, and which are known as Test-Solutions. The following are official in the U.S., Br., and German Pharmacopoeias : Qualitative Test-Solutions. 1943. Test-Solution Acetate of Copper. Br.— Subacetate of Copper of Commerce in fine powder (Verdigris) y z ounce av., Acetic Acid 1 fi. ounce, distilled Water a sufficiency. Dilute the Acid with half a ll. ounce of Water; digest the Subacetate of Copper in the mixture at a temperature not exceed- ing 2 1 2 F. (100 C), with repeated stirring, and continue the heat until a 580 LIQUORES — SOLUTIONS. dry residue is obtained. Digest this in 4 ounces of boiling distilled Water, and by the addition of more of the Water make up the Solution to 5 flounces, and filter. 1944. Test-Solution Acetate of Lead. U. S.— Acetate of Lead 1 part, distilled Water 10 parts. Dissolve, and, if necessary to give a faint acid reaction, add a few drops of Acetic Acid. 1945. Test-Solution Acetate of Potassium. Br. — Acetate of Potas- sium %. ounce av., distilled Water 5 fl. ounces. Dissolve, and filter. 1946. Test-Solution Acetate of Sodium. Br. — Acetate of Sodium >£ ounce, distilled Water 5 fl.ounces. Dissolve, and filter. The German Solu- tion is made by dissolving 1 part Acetate of Sodium in 4 parts of Water. 1947. Test-Solution of Albumen. U. S.— A Solution recently prepared by triturating the White of one Egg with 100 cubic centimetres of distilled Water, and filtering through cotton moistened with distilled Water. The Br. Solution is the White of one Egg mixed with 4 fl.ounces of distilled Water, and filtered through tow. 1948. Test-Solution Ammonio-Nitrate of Silver. U. S.— A Solution prepared by adding Water of Ammonia in drops to Test-Solution Nitrate of Silver until the precipitate at first formed is very nearly all dissolved, and fil- tering. The Br. Solution is Nitrate of Silver in crystals %. ounce av., Solu- tion of Ammonia X A-ounce, or a sufficiency, distilled Water a sufficiency. Dissolve the Nitrate of Silver in 8 fl.ounces of the Water and add Ammonia until the precipitate first formed is nearly dissolved, filter, and add enough distilled Water to make 10 fl.ounces. 1949. Test-Solution Ammonio-Sulphate of Copper. U. S. — Add Water of Ammonia in drops to Test-Solution Sulphate of Copper until the precipitate first formed is nearly all dissolved, and filter. The Br. formula is Sulphate of Copper in crystals y 2 ounce av., Solution of Ammonia a suffici- ency, distilled Water a sufficiency. Dissolve the Copper salt in 8 fl.ounces of Water, and cautiously add Solution of Ammonia until the precipitate first formed is nearly dissolved, then filter, and add distilled Water to make 10 fl.ounces. 1950. Test-Solution Ammonio-Sulphate of Magnesium. Br. — Sul- phate of Magnesium 1 ounce av., Chloride of Ammonium % ounce av., Solu- tion of Ammonia y 2 fl.ounce, distilled Water a sufficiency. Dissolve the Sulphate of Magnesium and Chloride of Ammonium in 8 ounces of distilled Water, and add the Water of Ammonia and sufficient distilled Water to make 10 fl.ounces. 1951. Test-Solution Bichromate of Potassium. U. S. — Bichromate of Potassium 1 part, dissolved in 10 parts of distilled Water. 1952. Test-Solution Bitartrate of Sodium. U. S. — Bitartrate of Sodium 1 part, dissolved in 10 parts of distilled Water, by the aid of heat, and filtered when cold. LIQUORES — SOLUTIONS. 581 1953. Test-Solution Boric Acid. Br. — Boric Acid 50 grains, dissolved in rectified Spirit 1 fl.ounce, and filtered. 1954. Test-Solution Bromine. Br.— Bromine 10 minims, distilled Water 5 fl.ounces. Place the Bromine in a bottle, pour on the Water and shake several times. Keep closely stopped and from the light. I 955- Test-Solution Carbonate of Ammonium. U. S.— Carbonate of Ammonium 1 part, dissolved in distilled Water 10 parts. The Br. formula is Carbonate of Ammonium y z ounce, Solution of Ammonia % fl.ounce, dis- tilled Water 10 fl.ounces. The German formula is Carb. Ammonium 1 part, Water of Ammonia 1 part, Water 3 parts. 1956. Test-Solution Carbonate of Sodium. G. P. — Prepared by dis- solving 1 part of Carbonate of Sodium in crystals in 4 parts of Water. 1957. Test-Solution Chloride of Ammonium. Br. — Chloride of Am- monium 1 ounce av., dissolved in distilled Water 10 fl.ounces, and filtered. The G. P. formula is 1 part to 9 of Water. 1958. Test-Solution Chloride of Barium. U. S. — Chloride of Barium, pure, 1 part, dissolved in distilled Water 10 parts, and filtered. The Br. for- mula is the same. 1959. Test-Solution Chloride of Calcium. U. S. — Chloride of Cal- cium, pure, 1 part, dissolved in distilled Water 10 parts, and filtered. The G. P. formula is 1 part to 9 of Water. i960. Test-Solution Chloride of Gold. U. S— Chloride of Gold 1 part, dissolved in distilled Water 20 parts. 1961. Test-Solution Chromate of Potassium. U. S. — Chromate of Potassium 1 part, dissolved in distilled Water 10 parts. The German for- mula is 1 part to 9 of Water. 1962. Test-Solution of Ferric Chloride. U. S. — Ferric Chloride 1 part, dissolved in distilled Water 10 parts, and filtered. The German formula is the official Solution Chloride of Iron. 1963. Test-Solution Ferricyanide of Potassium. U. S.— Ferricyanide of Potassium, pure, 1 part, dissolved in 10 parts of distilled Water. The Br. formula is % ounce of the salt in 5 ll.ounces of distilled Water. The Ger- man, 1 part to 9 of Water. 1964. Test-Solution Ferrocyanide of Potassium. U.S. — Kerrocyanide of I'otassium 1 part, dissolved in distilled Water 10 parts. The Br. formula is X ounce of the salt, dissolved in 5 ll.ounces of distilled Water. 1965. Test-Solution Ferrous Sulphate. U. S. — A recently-prepared Solution made by dissolving 1 part of selected clear crystals of Ferrous Sul- phate in 10 parts of distilled Water. 1966. Test-Solution of Gelatin. U. S.— Gelatin or Isinglass 1 part, soaked for half an hour in Water, and dissolved in distilled Water 50 parts, by the 582 LIQUORES — SOLUTIONS. heat of a water-bath. The Br. formula for Solution of Isinglass is : Isin- glass 50 grains, warm, distilled Water 5 flounces, made in the same way. 1967. Test-Solution Hydrosulphuric Acid. U. S.— A saturated Solu- tion of Hydrosulphuric Acid Gas in distilled Water. 1968. Test-Solution Hyposulphite of Sodium. U. S.— Hyposulphite of Sodium 1 part, dissolved in distilled Water 10 parts. 1969. Test-Solution of Indigo. U. S. — A liquid prepared by digesting 1 part of Indigo in powder with 12 parts of Sulphuric Acid on a water-bath for 1 hour, pouring the Solution into 500 parts of Sulphuric Acid, then leav- ing the mixture to subside and decanting the clear portion to use. 1970. Test-Solution of Iodide of Mercury and Potassium. U. S. — Made by adding 100 parts of Test-Solution of Mercuric Chloride to 367 parts of Test-Solution of Iodide of Potassium. 197 1. Meyer's Test-Solution, which is similar to the foregoing, and is frequently referred to in pharmaceutical works, is made by dissolving 49.8 grammes of Iodide of Potassium in 400 cubic centimeters of distilled Water and 13.546 grammes of Corrosive Chloride of Mercury in 500 cubic centime- ters of distilled Water, adding the latter solution to the former and enough distilled Water to make 1 litre. This is the standard Test-Solution or reagent for Alkaloids, which it precipitates, and the percentage of which may be calculated by the quantity of the solution required to precipitate them. 1972. Test-Solution Iodide of Potassium. U. S. — Iodide of Potassium 1 part, dissolved in distilled Water 20 parts. The Br. Solution is 1 to 10, the German 1 to 9. 1973. Test-Solution of Iodine. U. S. — Iodine 1 part, Iodide of Potas- sium 3 parts, Water 50 parts. Dissolve the Iodide of Potassium in the Water and add the Iodine to the solution. 1974. Test-Solution of Magnesium. U. S. — Sulphate of Magnesium 1 part, Chloride of Ammonium 2 parts, dissolved in 8 parts of distilled Water, and Water of Ammonia 4 parts added to the Solution. Allow to stand two or three days, and filter. The Br. Solution Ammonio-Sulphate of Magne- sium (1950) is similar to this but different in proportions. I 975- Test-Solution of Mercuric Chloride. U. S. — Mercuric Chloride 1 part, dissolved in distilled Water 20 parts. 1976. Test-Solution Nitrate of Barium. U. S. — Nitrate of Barium 1 part, dissolved in 20 parts of distilled Water. The G. P. formula is 1 part to 19 of Water. 1977. Test-Solution Nitrate of Silver. U. S. — Nitrate of Silver 1 part, dissolved in distilled Water 20 parts. 1978. Test-Solution Oxalate of Ammonium. U. S.— Oxalate of Am- monium 1 part, dissolved in distilled Water 20 parts. The Br. formula is LIQUORES — SOLUTIONS. 583 Oxalate of Ammonium l / 2 ounce, dissolved in warm distilled Water 20 fl.ounces (Imperial). 1979. Test-Solution Permanganate of Potassium. U. S. — Perman- ganate of Potassium 1 part, dissolved in distilled Water 1,000 parts. 1980. Test-Solution Phosphate of Ammonium. U. S. — Phosphate of Ammonium 1 part, dissolved in distilled Water 10 parts. 1981. Test-Solution Phosphate of Sodium. U. S.— Phosphate of Sodium 1 part, dissolved in distilled Water 10 parts. The Br. formula is the same. The G. P. directs 1 part to 19 of Water. 1982. Test-Solution Picric Acid. U. S. — A saturated Solution pre- pared by dissolving 1 part of Picric Acid in 100 parts of distilled Water, by aid of heat, and filtering after 24 hours. 1983. Test-Solution Platinic Chloride. U. S.— Platinic Chloride 1 part, distilled Water 20 parts. Dissolve, and filter. The Br. formula con- verts Metallic Platinum into a solution of Perchloride of Platinum. 1984. Test-Solution Potassio-Cupric Tartrate. U.S. — Dissolve 6^ grammes of selected crystals of Sulphate of Copper in 20 cubic centimeters of distilled Water; dissolve 36 grammes of Tartrate of Potassium in 140 cubic centimeters of Solution of Soda, then add the former solution gradu- ally to the latter, with stirring, and finally add sufficient Solution of Soda to make the measure 200 cubic centimetres. 1985. Test-Solution Potassio-Mercuric Iodide. Br. — Nessler's Rea- gent. — Iodide of Potassium 135 grains, Perchloride of Mercury a sufficiency, Caustic Soda 2 ounces av., distilled Water 1 pint (20 ounces Imperial). Dis- solve the Iodide of Potassium and 100 grains of Perchloride of Mercury in 15 fl.ounces of boiling distilled Water. To this add more aqueous Solution of Perchloride of Mercury until the precipitate produced no longer continues to disappear on well stirring, and a slight permanent precipitate remains ; then add the Caustic Soda. When the latter has dissolved add a little more of the aqueous Solution of Perchloride of Mercury, shake, allow to settle, and dilute the whole with Water to 20 fl.ounces (Imperial). This is used the same as Meyer's Solution as a reagent for alkaloids, etc. 1986. Test-Solution Stannous Chloride. Br. — Granulated Tin 1 ounce av., Hydrochloric Acid 3 fl.ounces, distilled Water sufficient to make 5 fl.ounces. Dilute the Acid in a flask with 1 ounce of Water and apply heat gently until gas ceases to be evolved, then add enough Water to make 5 fl.ounces, leaving the undissolved Tin in the bottle. 1987. Test-Solution Sulphate of Calcium. U. S. — A saturated Solu- tion made by digesting 1 part of powdered native crystallized Sulphate of Calcium with about 300 parts of distilled Water at the ordinary temperature. With repeated agitation for several days, then decanting the clear liquid, 1988. Test-Solution Sulphate of Copper. U. S.— Sulphate of Copper selected crystals 1 part, dissolved in distilled Water 10 parts. 584 LIQUORES — SOLUTIONS. 1989. Test-Solution Sulphate of Magnesium. G. P. — Sulphate of Magnesium 1 part, dissolved in Water 9 parts. 1990. Test-Solution Sulphate of Potassium. U. S. — Sulphate of Potassium 1 part, dissolved in distilled Water 15 parts. 1991. Test-Solution Sulphate of Silver. U. S. — Sulphate of Silver 1 part, dissolved in distilled Water 250 parts, by the aid of gentle heat. 1992. Test-Solution Sulphide of Ammonium. U.S. — Made by passing washed Hydrosulphuric Acid Gas into 3 parts of Water of Ammonia until the latter is saturated, then adding 2 parts of Water of Ammonia. The Br. Solution Sulphydrate of Ammonium is the same. 1993. Test-Solution Sulphite of Sodium. G. P. — Dissolve 1 part of the Salt in 9 parts of Water. 1994. Test-Solution Tannic Acid. U. S.— Tannic Acid 1 part, dis- solved in 9 parts of Water and 1 part of Alcohol. The G. P. directs 1 part of Tannic Acid to 1 9 of Water. 1995. Test-Solution Tartaric Acid. U. S. — Tartaric Acid 1 part, dissolved in distilled Water 5 parts. The G. P. directs 1 part to 4 parts of Water. The Br. formula is Tartaric Acid 1 ounce av., distilled Water 8 H. ounces, Rectified Spirit 2 fl.ounces. 1996. Test-Solution Yellow Chromate of Potassium. Br. — Red Chro- mate of Potassium 295 grains, Bicarbonate of Potassium 200 grains, distilled Water 10 fl.ounces. Dissolve the Red Chromate of Potassium in the Water and exactly neutralize the solution with the Bicarbonate evolution of all Carbonic Acid, being insured by ebullition, then filter. 1997. Tincture of Phenol-Phthalein. Br.— Phenol-phthalein 1 grain, Proof Spirit 100 grains. Dissolve. Volumetric Solutions. Volumetric Solutions are used for determining the quantity of a chemical salt contained in a given quantity of a solution. They are used for quantitative chemical analysis only, the ordinary test solutions being sufficient for qualitative analysis and the general uses of the pharmacist. As the U. S., Br., and Gr. formulas are nearly the same, the U. S. only will be given. For the equivalents of these solutions refer to the Pharmacopoeia. 1998. Volumetric Solution Bichromate of Potassium. — Bichromate of Potassium 14.75 grammes, distilled Water, a sufficient quantity to make 1000 cubic centimeters, or 1 litre. Dissolve the Bichromate of Potassium in about LIQUORES — SOLUTIONS. 585 700 cubic centimeters of distilled Water, then add of the latter enough to make the solution measure 1000 cubic centimeters. 1999. Volumetric Solution Hyposulphite of Sodium.— Hyposulphite of Sodium 32 grammes, Volumetric Solution of Iodine 100 cubic centimeters, distilled Water, a sufficient quantity to make 1000 cubic centimeters. Dis- solve the Hyposulphite of Sodium in enough distilled Water to make the solution measure 1000 C.c. To the Volumetric Solution of Iodine (which should measure exactly 100 C.c.) add a sufficient quantity of the Solution of Hyposulphite of Sodium, from a burette, nearly to decolorize the Iodine Solution, then add freshly gelatinized starch and continue the addition of the Hyposulphite until the blue color of the mixture is just destroyed, noting the number of cubic centimeters added. Then take of the Solution of Hyposulphite of Sodium ten times this number of cubic centimeters, and add thereto enough distilled Water to make the solution measure 1000 cubic centimeters. 2000. Volumetric Solution of Iodine. — Iodine 12.66 grammes, Iodide of Potassium 18 grammes, distilled Water a sufficient quantity to make 1000 cubic centimeters. Dissolve the Iodide of Potassium in about 700 cubic centimeters of distilled Water ; in this solution dissolve the Iodine and add enough distilled Water to make the solution measure 1000 cubic centimeters. 2001. Volumetric Solution Nitrate of Silver. — Nitrate of Silver, well crystallized and dry, 16.97 grammes, distilled Water a sufficient quantity to make 1000 cubic centimeters. Dissolve the Nitrate of Silver in about 700 parts of distilled Water and add enough of the latter to make the solution measure 1000 cubic centimeters. 2002. Volumetric Solution of Oxalic Acid.— Oxalic Acid in perfect crystals 63 grammes, distilied Water a sufficient quantity to make 1000 cubic centimeters. Dissolve the Oxalic Acid in about 700 cubic centimeters of distilled Water and add of the latter enough to make the solution measure 1000 cubic centimeters. 2003. Volumetric Solution of Soda. — Oxalic Acid in perfect crystals 6.3 g rarn mes, Solution of Soda, Distilled Water, of each a sufficient quantity. To the Oxalic Acid, add from a burette enough Solution of Soda exactly to neutralize the Acid, as indicated by the color of litmus, and note the number of cubic centimeters of Solution of Soda required. Take 10 times this number of cubic centimeters of the same Solution of Soda and add thereto enough distilled Water to make the solution measure 1000 cubic centimeters. Other Solutions. Besides the Solutions for which the formula' have been given in the preceding sections, quite a number art.: know n and 586 LIQUORES — SOLUTION: used which cannot well be included in the classes named, and are therefore given under this heading : 2004. Solution Albuminate of Iron.— Dried Egg Albumen, soluble. 1 ounce av\, dissolve in Water 7 n.ounces and add to the Solution 75 grains crystallized Chloride of Iron dissolved in 3 rl. ounces of Water, then add to the Solution 2 n.ounces of Alcohol mixed with 4 rl. ounces of Glycerin, and mix them well together. By omitting the Glycerin and Alcohol this Solution may be evaporated by gentle heat to a thick syrup, which may be spread on glass and obtained in the form of a scale salt Albuminate of Iron. See, also. Albuminate of Iron and Sodium (syrups). 2005. Battery Solutions or Fluids.— The Solution most commonly used for batteries of Zinc and Copper, which are called Gravity Batteries, is a Solution of Sulphate of copper (Blue Vitriol) in Water, sufficient of the salt being used to leave a small portion undissolved in the bottom of the jar. The batteries with Carbon and Zinc plates, known as High Resistance Bat- teries, are charged with a Battery Fluid made with Bichromate of Potassium 1 part, Sulphuric Acid 2 parts by weight, Water 10 parts, the Zincs being amalgamated with Mercury. The Leclanche Battery, which has a porous cup filled with Carbon, and a Zinc annode, is charged with a Solution of Chloride of Ammonium about 1 part to 4 parts of Water. Small Batteries, for medicinal use, are usually made with Copper and Zinc and charged with a Solution of Sulphate of Mercury. Platinum Batteries are charged with the same, some Mercury being left in the bottom of the jar, which keeps the Zincs amalgamated. Many other kinds of batteries are known and used, but these mentioned are the most common. 2006. Disinfecting Solutions. — To give formulas for all the Disinfecting Solutions which have been used would require a volume. We can, therefore, only mention those which have been best known and have most merit. The formulas for many of them are given under other headings, as Solution of Chlorinated Lime, Solution of Chlorinated Soda, Solution Chloride of Zinc, etc., nearly all having in them free or combined Chlorine, which is considered the best available disinfectant. 2007. Solution Bromo-Chloralum. — Under the name Bromo-Chloralum, put up by Tilden & Co., a Solution for disinfecting, etc., is well known. A similar preparation may be made as follows : Alum 1 1 ounces av., Carbonate of Sodium (Sal Soda) 10 ounces av., Bromide of Potassium 8 ounces av., Hydrochloric Acid a sufficient quantity, Water sufficient to make a gallon. Dissolve the Alum in 6 pints of boiling Water and add the Carbonate of Sodium to the Solution, which precipitates Hydrate of Aluminium ; add to the mixture sufficient Hydrochloric Acid to dissolve the precipitate, then dis- solve the Bromide of Potassium in the Solution, and, if necessary, add sufficient Water to make the measure 1 gallon. 2008. Condy's Fluid or Solution. — A Solution of Permanganate of Potassium, made by dissolving ]/ z ounce Permanganate of Potassium in 1 LIQUORES — SOLUTIONS. 587 gallon of Water. By using the crude salt a very cheap and efficient disin- fectant may be made. This Solution is also a valuable wash for foul ulcers and sores. 2009. Coutaret's White Fluid or Solution. — Sulphate of Zinc 1 '- ounce av., Water sufficient to make a pint. 2010. Darby's Prophylactic Fluid or Solution.— Permanganate of Potas- sium 5 grains, Sulphate of Potassium 150 grains, Carbonate of Potassium \%. ounce av., Chloride of Potassium X ounce av., Water sufficient to make a pint. 201 1. De Wessely's Disinfecting Solution. — Sulphate of Iron 1 ounce av., Chloride of Iron 3^ ounces av., Chloride of Zinc iy& ounce, Water sufficient to make a pint. 2012. Farwell's Disinfectant Solution. — Sulphate of Iron 2)4, ounces av., Carbolic Acid 5 drachms, Water sufficient to make a pint. 2013. Girondin Disinfectant Solution. — Sulphate of Zinc 4% ounces, Sulphate of Copper ]4- ounce, Sulphate of Lime yi ounce, Water sufficient to make a pint. 2014. Grantville Carbolic Alkali. — Carbolic Acid ^ ounce, Caustic Potassa 1 50 grains, Water sufficient to make a pint. 2015. Le Doyen's Disinfectant Solution. — Nitrate of Lead 2}£ ounces av.. Water sufficient to make a pint. 2016. Mattenheimer's Disinfecting Fluid. — Sulphate of Iron 1 ounce, Carbolic Acid 7 drachms, Water, sufficient to make a pint. 2017. Monsell's Disinfecting Solution.— Solution of Subsulphate of Iron to 4 ounces being required according to the consistence of the Extract. This solution is about 30 per cent, stronger than Tincture of Opium, and is claimed to be superior to it as some of the objectionable principles of ( )pium are removed. 2028. Liquor of Opium is another name for Acetum Opii or Black Drop (20 and 21). 2029. Liquor Opii Hydrochloricus, or solution Muriate of Opium is made with Powdered Opium, 1 1 / 2 ounce av., Distilled Water, 20 fl.ounces, Hydrochloric Acid, 1% fl. ounce. Digest for two weeks, agitating daily and filter. It is about the same strength as Tincture Opium, and does not con- tain some of the objectionable principles of Opium. Liquor Opii Citratis is made in the same manner, except that Citric Acid is used instead of Hydrochloric. 2030. Solution Per-Oxide of Hydrogen. — This solution is most con- veniently made by decomposing 1 part of Dioxide of Barium with 2 parts of Hydrochloric Acid, Chloride of Barium precipitates leaving Hydrogen Di- oxide Cor Per-oxide) in solution. The solution is not very stable. It is chiefly used for bleaching hair, which can be made of a golden or blonde color by applying it. It is seldom made except by manufacturing chemists, and as found in the market will yield from 10 to 20 volumes oxygen gas for each volume of the solution. 2031. Solution Phosphorus, Thompson's. Phosphorus, not oxidized 1 grain. Absolute Alcohol 5 fl. drachms. Glycerin ij£ fl.ounces. Alcohol 2 fl. drachms. Spirit of Peppermint 40 minims. Dissolve the Phosphorus in the Absolute Alcohol, contained in a well stopped bottle, by the aid of gentle heat, and having mixed and warmed the Glycerin, Alcohol and Spirit of Peppermint to about 150° F., add them to the solution, agitating them well together. The solution should be kept 590 LIQUORES — SOLUTIONS. closely stopped in a dark place. A H. drachm contains fa grain of Phos- phorus. The dose is 20 minims or more. 2032. Solution Phosphorus Compound. Phosphorus Bromine and Iodine. Phosphorus 10 grains. Bromine, 1 70 grains. Iodine 1 70 grains. Alcohol 1 fl. ounce. Glycerin, sufficient to make 8 fl.ounce. Dissolve the Iodine in the Alcohol and add the Solution to the Glycerin, then add the Bromine a little at a time, and when combined with the Solu- tion add the Phosphorus, in small portions, keeping the bottle well stopped during its solution. The Phosphorus should be added in fine shavings kept under water until used, and great care must be used in adding it, as the action is violent. This solution is used in making some syrups, wines, etc. 2033. Solutions for Plating. — For electro-plating with silver, nickei, gold, etc., it is necessary to use batteries to generate the electrolytic action, and deposit the metals from their solutions upon the surfaces which are to be plated. The details of the processes are too voluminous to be repeated here, and the solutions from which the metal is deposited can only be briefly men- tioned. Silver-Plaiing Solution. This may be made with Cyanide of Potassium, 4 ounces av., Cyanide of .Silver, \%. ounce av., Water, 160 fl. ounces. Gold-Plating Solution. This may be made with Cyanide of Potassium, 1 pound av., Cyanide of Gold, T J 5 ounce av., Water, 160 fl. ounces. Nickel-Plating Solution. This may be made with double Salts of Nickel (Sulphate of Nickel and Ammonium), 4 ounces, Water, 160 fl. ounces. Many other Plating Solutions are used, and the metal is deposited in vari- ous ways on different articles. Plate Liquor is intended to brighten and increase the luster of plated- ware. It is made by dissolving 1 ounce each of Alum, Cream of Tartar and Salt, in 80 fl. ounces of Water. The articles are to be boiled in the Liquor. 2034. Solutions for Preserving Fruit, etc.— Salicylic Acid 1 ounce av., Boric Acid 4 ounces av„ Water 10 pints. Dissolve the salts in the Water by the aid of heat. Use 2 ounces of this Solution for each quart of fruit which it is desired to put up, adding sugar, etc., in the regular way. This Solution may be used for all soft fruits, berries, etc. Vegetable Preserving Solution. — Salicylic Acid 1 ounce av., Boric Acid 4 ounces av., Rock Salt 8 ounces, Alum 1 ounce, Water sufficient to make 10 pints. Mix and dissolve by the aid of heat. Use 3 ounces of this Solution for each quart of corn, peas, beans, or other vegetables desired to be preserved, cooking them as usual before canning. LIQUORES — SOLUTIONS. 591 Pickle Preserving Solution — For preserving pickles in casks : Cider Y'inegar 10 gallons, Rock Salt 10 pounds, Alum, in powder, X pound, Cap- sicum 2 ounces, Cloves i ounce, Salicylic Acid i ounce. Mix and dissolve. Wash the cucumbers thoroughly and pack them in the cask until nearly full, then add sufficient of the Solution to cover them thoroughly. 2035. Silvering Solution. — For silvering the inside of glass vessels, vases, etc., the following Solution is used : No. 1. — Distilled Water 12 fl.ounces, Rochelle Salt 12 grains, Nitrate of Silver 16 grains. Dissolve the Rochelle Salts in the Water and heat to boil- ing, then add the Nitrate of Silver dissolved in 1 ounce of distilled Water and continue the boiling for 10 minutes, adding enough distilled Water, when cold, to make the measure 12 fl.ounces. No. 2. — Distilled Water 10 fl.ounces, Nitrate of Silver 1 ounce, Water of Ammonia a sufficient quantity, Alcohol 1 fl.ounce. Dissolve the Silver Salt in the Water and add enough Water of Ammonia to nearly, but not quite, dissolve the precipitate first formed ; lastly, add the Alcohol, and distilled Water enough to make the measure 12 fl.ounces. Allow the Solutions to stand several days, then mix equal parts of each, and pour into the glass vessels desired to be silvered, or, for making mirrors, lay glass flat on the surface of the Solution. 2936. Soldering Solution. — Hydrochloric Acid 5 fl.ounces, Zinc, in small pieces, a sufficient quantity, Sal Ammoniac 1 ounce av. Add the Zinc to the Acid until nearly all has dissolved that will, then add the Sal Ammoniac and heat to a simmer for five minutes. For making Solder flow freely. 2037. Solution of Salicylate of Sodium. Salicylic Acid 1 ounce av. Bicarbonate of Sodium }( ounce av. Alcohol, 4 fl.ounces. Glycerin, 4 fl.ounces. Water, sufficient to make 1 pint. Mix the Salicylic Acid with 6 fl.ounces of Water, in a capacious bottle- and add the Bicarbonate of Sodium in portions. When effervescense has ceased and the salts are dissolved add the Alcohol and Glycerin and enough Water to make the measure a pint. This Solution is given for rheumatism, gout, etc., in doses of a teaspoonful to a tablespoonful. 2038. Solution of Strychnine, Hall's. Sulphate of Strychnine, in crystals, 16 grains. Alcohol, 8 II. ounces. Water, 7>£ fl.ounces. Diluted Sulphuric Acid, q. s., or % Rub the Strychnine salt to a fine powder and then, with the Alcohol, add the Water to the Solution, and then the diluted Sulphuric Acid yi ounce or 502 LIQUORES — SOLUTIONS. LITHIUM. sufficient to make a perfectly clear Solution without precipitation, and Water, if necessary, to make the Solution measure a pint. A fl.ounce of this Solution contains i grain of the Strychnine salt. It is a very convenient Solution for prescribing and for dispensing purposes, but is not generally used for combining with elixirs, etc., the stronger Solution Sulphate of Strychnine (1942), 1 grain in a fl. drachm, being generally used for this purpose. 2039. Solution of Sulphurated Lime.— This Solution is made by boiling together in a porcelain vessel for one hour sublimed Sulphur y/ z ounces av., Lime 7 ounces av., Water 2 pints, stirring and adding Water occasionally to preserve the volume. . The vessel is then removed from the fire and set aside for the sediment to subside ; the clear Solution is then poured off. It is used as an application or wash for itch and other similar parasites in the skin. 2040. Solution of Tar or Pitch, Alkaline. — Purified Tar 2 parts, Caus- tic Potassa 1 part, Water 7 parts. Mix and stir frequently for 24 hours, then let it settle and pour off the clear Solution from the sediment. It is used externally like tar. 2041. Solution Tartar Emetic. — Tartar Emetic 30 grains, Alcohol 4 fl. ounces, boiling Water 12 fl. ounces. Dissolve the salt in the Water and when cool add the Alcohol and sufficient Water to make a pint. This is the same strength as Wine of Antimony, but preferable to it, as the salt is not precipitated by the astringent properties of the wine. 2042. Solution of Tin — Solution of Muriate or Chloride of Tin, Tin Liquor, Cochineal Compottnd, Madder Compound. — This may be made by dissolving granulated Tin 1 pound av., in a mixture of commercial Muri- atic Acid 5 pounds, commercial Nitric Acid 1 pound, with Water sufficient to make a gallon. It may also be made by dissolving crystallized Chloride of Tin 1 pound in a mixture of commercial Hydrochloric Acid i}4 pound av. with Water suf- ficient to make a gallon. This Solution is used as a mordant in dyeing. LITHIUM. Symbol, Li., Atomic weight, 7 ; sp. gr., 0.589. Lithium is the lightest of all the known metals, and belongs to the alkaline group, being similar to Potassium and Sodium, although not so ready as they are to combine with Oxygen. It was first obtained by Sir H. Davy, by exposing Hydrate of LITHIUM. Lithium in contact with Mercury to galvanic action, and de- composing the amalgam thus formed by distilling off the Mercury, leaving the metallic Lithium. It is white, and fuses at 356° F. Lithium forms chemical combinations with the Acids and the Haloid Elements, several of which are official, the salts being used chiefly for kidney troubles and rheumatism. The following are the official Salts of Lithium. 2043. Lithii Benzoas. Benzoate of Lithium. The U. S. P. does not give a formula for this Salt, but it may be made conveniently by Shuttleworth's process : Car- bonate of Lithium 1 ounce av. is mixed in a capsule with 9 fl.- ounces of- Water and heated, then 3^ ounces av., of Benzoic Acid is added in small portions and the heat continued until the Carbonate of Lithium is decomposed and effervescense has ceased. The solution is then filtered, concentrated by evap- oration, and crystallized or evaporated to dryness on a water- bath. Uses. — This Salt is a favorite remedy with physicians for gout and rheumatism. The dose is 15 to 20 grains. 2044. Lithii Bromidum. Bromide of Lithium. LiBr. This is official in the U. S. P., and may be made by dissolv- ing Carbonate of Lithium to saturation in Hydrobromic Acid, or by decomposing a solution of Bromide of Potassium with a solution of Sulphate of Lithium. It is also prepared in other ways, but is seldom made except by manufacturing chemists. Uses. — Bromide of Lithium is employed as a hypnotic, especially in rheumatic affections. It is one of the most effi- cient of Bromides. The dose is from 1 5 to 30 grains. 594 2045- Lithii Carbonas. Carbonate of Li thin in. LiC0 3 . This Salt is official in the U. S., Br., and German Pharma- copoeias. It may be most readily prepared by decomposing a strong solution of Sulphate of Lithium with a strong solution of Carbonate of Ammonium, Carbonate of Lithium being precipitated, which is washed with a little Alcohol and dried. It resembles Carbonate of Magnesium. In a commercial way it is obtained by fusing the mineral Lepidolite with Carbonate of Barium, Sulphate of Barium and Sulphate of Potassium, and then separating the Potassium and Lithium Sulphates which rise to the surface by lixivation, and prepar- ing the Carbonate from them as above. Uses. — This is used as the basis for preparing most of the Lithium Salts, and is given in doses of 2 to 10 grains, and used as an injection suspended in mucilage water, for urinary calculi. 2046. Lithii Citras. Citrate of Lithium. Li 3 C 6 H 5 7 . This Salt is official in the U. S. and British Pharma- copoeias, the latter giving the following formula : Carbonate of Lithium, 50 grains. Citric Acid, 90 grains. Warm Distilled Water, 1 fl. ounce. Dissolve the Citric Acid in the Water, and add the Carbon- ate of Lithium in successive portions, applying heat until effervescense ceases and a perfect solution is obtained. Evap- orate by a steam or sand bath, until the product has a specific gravity of about 1.230 and set aside for crystals to form. Dry the crystals and preserve them in a stoppered bottle. Uses. — The Citrate of Lithium is a soluble salt, conveni- ent for using in solutions, etc. The dose is 15 to 20 grains. LITHIUM. 595 2047. Lithii Salicylas. Salicylate of Lithium. 2LiC,H g 3 .H 2 0. This is official in the U. S. P., and is conveniently prepared by adding to 1 fl. ounce of Water 60 grains of Carbonate of Lithium, and then heating to boiling and gradually adding 220 grains of Salicylic Acid, and continuing the heat until effer- vescence ceases, then filtering and evaporating to dryness on a water-bath. Uses. This is used for gout, rheumatism, etc., in doses of 20 to 40 grains. It seems to be more effective than other salicylates for this use. Other Lithium Salts. The foregoing official Lithium Salts are all that are used to any extent in medicine, but the following are known and sometimes called for: 2048. Borocitrate of Lithium. — Citric Acid, 10 parts, Lithium Carbon- ate, 2 parts, Boric Acid, 3 parts, dissolved together in boiling water and care- fully evaporated to dryness and crystallized. 2049. Chloride of Lithium, LiCl. — Dissolve Carbonate of Lithium to saturation in Hydrochloric Acid, concentrate the solution by evaporation and crystallize. 2050. Diborocitrate of Lithium. — Citric Acid, 20 parts, Carbonate of Lithium, 7 parts, Doric Acid, 12 parts. Dissolve in boiling water and evapor- ate carefully to a dry powder. 2051. Iodide of Lithium, Lil. — Add Carbonate of Lithium to a solution of Iodide of Calcium until no more will dissolve when heated, then filter, concentrate and crystallize. 2052. Nitrate of Lithium, LiN0 8 . — Dissolve Carbonate of Lithium to saturation in Nitric Acid, concentrate the solution and crystallize. 2053. Oxide of Lithium is an Alkaline Earth, found in petalite, and in solution in many mineral waters. 2054. Phosphate of Lithium, Li 8 P0 4 . — This maybe made by dissolv- ing Carbonate of Lithium to excess in Phosphoric Acid, concentrating the solution and crystallizing. 596 LOTIONES — LOTIONS. 2055. Sulphate of Lithium, Li 2 S0 4 .H 2 0. — Dissolve Carbonate of Lith- ium to saturation in Sulphuric Acid, concentrate and crystallize. Many other Salts of Lithium may be made with other acid in the same manner as the foregoing. 2056. Effervescing Citrate of Lithium is" made by mixing Citric Acid, 4 parts, with Bicarbonate of Sodium, 5 parts, and Bicarbonate of Lithium, 1 part, and heating together in a flat vessel to about ioo° C, stirring continu- ally until granulated, then sifting through proper size sieves. LOTIONES — LOTIONS. Lotions are preparations intended to be applied externally for various purposes, and consisting of medicinal substances mixed with, dissolved or suspended in water, or other aqueous vehicles. A great number of Lotions were formerly known and used in medicine, but since the introduction of Glycerites, Oleates and other like preparations, by which the medicinal ingredients are more effectively applied, they have mostly gone out of use. Formulae will therefore be given for a few only of those best known and most liable to be called for. The two first given are official in the Br. P. Many of the liniments and solutions are frequently called Lotions. Other Lotions will be found under Toilet Preparations, etc. 2057. Lotio Hydrargyri Flava. Br. Yellow Mercurial Lotion — Yellow Wash — Aqua Phagedomica — Lotio Flava. Perchloride of Mercury (Corrosive Sublimate), ... 18 grains. Solution of Lime (Lime Water), 10 fl.ounces. Mix them. This is used as a wash for syphilitic sores, ulcers, etc. 2058. Lotio Hydrargyri Nigra. Black Mercurial Lotion — Black Wash — Lotio Nigra. Subchloride of Mercury (Calomel), 30 grains. Solution of Lime (Lime Water) 10 fl.ounces. Mix them. By adding 30 grains of powdered Acacia, this is greatly im- proved. This wash is applied on lint to syphilitic sores, ulcers, etc., and is frequently used as an injection for venereal diseases. LOTIONES — LOTIONS. 597 2059. Bateman's Lotion. — Corrosive Chloride of Mercury, 6 grains, Compound Spirit of Lavender, 3 fl. ounces. Dissolve, and add Water, 12 fl.ounces. Used for skin diseases. 2060. Fuller's Leg Wash. — Acetic Acid, 1 fl. ounce, Sal Ammoniac, x / z ounce av., Tincture of Aconite Root, 2 fl.ounces, Tincture of Asafetida, ]/ z fl.ounce. Mix and dissolve. A teaspoonful to a tablespoonful of this solution is used in a pint of water for washing horse's legs before or after racing. 2061. Gowland's Lotion. — Jordan or Sweet Almonds, 1 ounce, Bitter Almonds, l / 2 ounce. Soak them in water, remove the skin and mash them to a pulp in a mortar, add water by trituration to make a pint of emulsion. Add to this Corrosive Chloride of Mercury, 1 5 grains, dissolved in 4 fl.ounces of Alcohol, and 2 fl.ounces of Glycerin, and mix them well together. This is different than the original formula, by the addition of Alcohol as a preservative and Glycerin as an emollient. It is a fine cosmetic for the complexion, to remove sunburn, tan, freckles, etc., and is useful for skin diseases. 2062. Granville's Milder Lotion. — Stronger Water of Ammonia, 4 fl.ounces, Spirit of Rosemary, 3 fl.ounces, Spirit of Camphor, 1 fl.ounce. Mix them. This is used as a stimulating lotion. 2063. Granville's Stronger Lotion. — Stronger Water of Ammonia, 5 fl.ounces, Spirit of Rosemary, 2 fl.ounces, Spirit of Camphor, 1 ounce. This is also used as a stimulating Lotion, but is much stronger than the preceding. 2064. Hemorrhoidal Lotion. — Solid Extract of Stramonium, 120 grains, Tincture of Iodine, 2 fl. drachms, Glycerin, 8 fl.ounces, Water, 8 fl.ounces, powdered Golden Seal, 1 ounce, Tannin, 1 20 grains. Heat the Glycerin and Water and digest all, except the Tincture of Iodine, in the mix- ture for 6 hours, at a heat of not more than 175 F. Then filter, add enough water through the filter to make a pint of the filtrate, and mix with it the Tincture of Iodine. This is an excellent application for piles. 2065. Kirkland's Lotion or Lotion of Myrrh. — Tincture of Myrrh, 4 fl.ounces, Solution of Lime (Lime Water), 4 fl.ounces. Mix them. This is used for ulcers, spongy gums, etc. Compound Myrrh Lotion. — Honey of Roses. 2 fl. drachms, Tincture of Myrrh, 2 11. drachms, Lime Water, 2<4 fl.ounces. This is used as a denti- frice, etc. 2066. Moth and Freckle Lotion. — Bichloride of Mercury (Corrosive Sublimate), 60 grains, Chloride of Ammonium (Sal Ammoniac), 240 grains, Alcohol, 2 11. ounces, Rose Water or Orange Flower Water, 2 11. ounces. Rub the Corrosive Sublimate to a fine powder and dissolve it in the Alcohol. Dissolve the Chloride of Ammonium in the Water. Mix the solutions, add 598 MAGNESIUM. the Rose Water, and after standing a day or two filter. This may be applied once or twice daily, with a soft sponge, allowing it to dry on the skin. 2067. Palmer's Lotion. — Corrosive Chloride of Mercury, 8 grains, Alum, 1 2 grains, Water, a pint. Dissolve the salts in the water. This is used as an application for skin diseases, cuts, sores, etc., and is sometimes employed as a cosmetic. MAGNESIUM. Symbol, Mg. ; atomic weight, 24; sp. gr., 1.743. The metallic element Magnesium was first discovered by- Sir H. Davy in 1808, but was not isolated in a sufficient quan- tity for examination until 1830, when Bussy examined it and established its characteristics. It may be obtained commercially by heating to redness a mixture of Chloride of Magnesium, 6 parts, with fused Chlo- ride of Sodium 1 part, Fluoride of Calcium 1 part, and Sodium, in slices, 1 part. To prepare it chemically pure requires particular manipula- tion. It is furnished for laboratory use in the form of a ribbon. Magnesium in metallic form is used for making the brilliant Magnesium Light when acted upon by the oxy-hydrogen jet, and is the basis of all the Magnesium salts, which resemble those of Calcium and Barium, and form an important portion of the crust of the earth. The salts of Magnesium are considerably used in pharmacy and medicine. The following are the official salts : 2068. Magnesia. Light Magnesia — Calcined Magnesia — Oxide of Magnesium. — Magnesia Levis. MgO. This is made by heating Light Carbonate of Magnesium in a crucible to a low red heat until its carbon dioxide and water are expelled, or until a small portion, taken from the centre of the crucible and moistened with water, causes no MAGNESIUM. 599 effervescense when dropped into warm diluted Sulphuric Acid. Uses. — In pharmacy Magnesia is used for making some other preparations and given in doses of 10 to 30 grains as an antacid and laxative. It is usually called for and sold as Cal- cined Magnesia. 2069. Magnesia Ponderosa. Heavy Magnesia — Heavy Calcined Magnesia. MgO. This is the same chemically as the foregoing, but an equal weight is only about one fourth as bulky, It is prepared from Heavy Carbonate of Magnesium in precisely the same manner as the Light Magnesia. Husband's Magnesia and Henry s Magnesia are simply Heavy Magnesia put up in proprietary form and sold at a fancy price. Uses. — Heavy Magnesia is used for the same purposes as Light Magnesia, but is more convenient on account of being less bulky. The dose is 10 to 30 grains or more. 2070. Magnesia Carbonas. Carbonate of Magnesium. (MgC0 3 ) 3 Mg(HO) 2 . 4 H 2 0. The U. S. P. gives no formula for this preparation, but the Br. P. gives two processes, one for making Magnesii Carbonas Levis or Light Carbonate of Magnesia, the other for making Magnesii Carbonas Ponderosa or Heavy Carbonate of Magne- sium, the latter being generally used in pharmacy. The proportions of both arc the same, varying only in the manner of making. Heavy Carbonate of Magnesium, Br. Sulphate- of Magnesium 10 ounces av. Carbonate of Sodium 12 ounces av. Boiling Distilled Water, a sufficiency. Dissolve the Sulphate of Magnesium and the Carbonate of Sodium each in 20 ounces of the Water, mix the two solutions 6()() MAGNESIUM. and evaporate the whole to perfect dryness by means of a sand-bath. Digest the residue for half an hour with 2 pints (Imperial) of Water, and, having collected the insoluble mat- ter, wash it repeatedly with distilled Water until the washings no longer give a precipitate with Chloride of Barium. Finally, dry the product at a temperature not exceeding 212° F. (ioo° C). As prepared for the market this powder is pressed while still moist in bricks or squares of 2 or 4 ounces or less. Light Carbonate of Magnesia is made with the same ingredi- ents, in the same proportion, but the salts are dissolved each in half a gallon (imperial) of cold Water, the solutions mixed and boiled 15 minutes, then the precipitate is washed with boiling distilled Water, as above directed, and dried at a tem- perature not exceeding 212 ' F. (ioo° C). Milk of Magnesia. — By omitting to dry the precipitate as above prepared, and suspending it instead in as little water as will answer the purpose, Milk of Magnesia is produced. A proprietary article by this name has had a popular sale. Uses.— Carbonate of Magnesium is extensively used in pharmacy for various purposes, and in medicine is employed as an antacid and laxative, in doses of 20 to 60 grains or more. It is a familiar household remedy for "heart-burn," and is considerably used as a toilet powder, and in tooth powders, etc. 2071. Magnesii Citras Granulatus. Granulated Citrate of Magnesium. Carbonate of Magnesium, . 1 1 parts or 770 grains. Citric Acid, 48 parts or 2880 grains. Bicarbonate of Sodium, . . 37 parts or 2220 grains. Sugar, in No. 60 powder, . 8 parts or 480 grains. Alcohol, ) each a su ffi c ient quantity. Distilled Water, ) Mix the Carbonate of Magnesium intimately with 33 parts or 1980 grains of Citric Acid and enough distilled Water to make a thick paste, dry this at a temperature not exceeding MAGNESIUM. 601 30 C. (86° F.), and reduce it to a fine powder. Then mix it intimately with the Sugar, the Bicarbonate of Potassium, and the remainder of the Citric Acid, previously reduced to a very fine powder. Dampen the mass with a sufficient quantity of Alcohol and rub it through a No. 20 tinned-iron sieve to form a coarse granular powder. Lastly, dry it in a moderately warm place and put up in well-closed bottles. Uses. — This is given as an agreeable laxative, in doses of 1 to 3 teaspoonfuls, dissolved in cold water. A great number of effervescing salts may be made in the same general manner. 2072. Magnesii Sulphas. Sulphate of Magnesium — Epsom Salt. MgS0 4 . 7 H 3 0. This is prepared commercially by treating the earthy sili- cious Magnesium Hydrate with Sulphuric Acid. The mass is then dried and calcined at a red heat, to convert Ferrous Sul- phate into Red Oxide of Iron. It is then dissolved in Water and Sulphide of Calcium added to separate any portion of Iron remaining, and at last dissolved again and crystallized to make the Epsom Salt of commerce. For laboratory experiments Carbonate of Magnesium may be dissolved to saturation in Sulphuric Acid, the solution concentrated by evaporation and crystallized. Uses. — Sulphate of Magnesium is the commercial basis of most of the Magnesium Salts. It is extensively used as a medicine, being familiarly known as " Salts." It acts as a cathartic in doses of 1 ounce, and is used in smaller doses as a laxative and refrigerant. 2073. Magnesii Sulphis. Sulphite of Magnesium. MgS0 3 .6H 2 0. This Salt is now official in the U. S. P., and is readily made by passing .t current of purified Sulphurous Acid Gas into a 602 MAGNESIUM. rather thick milk of Magnesia, until the Acid is in slight excess. Uses. — This salt is employed for the same purposes as Sul- phite of Sodium and Sulphate of Potassium, but is less solu- ble and therefore less disagreeable to the taste. The dose is 15 to 30 grains. Other Magnesium Salts. The foregoing Official Salts of Magnesium are all that are much used in pharmacy or medicine, but as it combines with most of the Acids and the non-metals, a great number of other preparations are known. The following are the more im- portant unofficial Salts : 2074. Acetate of Magnesium. — Mg (C 2 H 3 2 )2. — Made by adding Carbonate of Magnesium to saturation to Acetic Acid, filtering the solution, concentrating and crystallizing. 2075. Bromide of Magnesium. — This is most conveniently made by add- ing Carbonate of Magnesium in excess to a solution of Bromide of Iron, then filtering, concentrating and crystallizing. 2076. Chloride of Magnesium. — MgCl. — This is a very deliquescent Salt, made by neutralizing Hydrochloric Acid with Magnesia, evaporating to dryness, adding an equal weight of Chloride of Calcium, heating in a red-hot platinum crucible, and fusing. 2077. Citrate of Magnesium. — Mg 3 (C 6 H 5 7 ) 2 . — This Salt is but little used, the effervescing Citrate being generally employed. It may be made by dissolving Citric Acid 3 parts in Water, yi part by the aid of heat, and adding to the solution 1 part of Magnesia and stirring them together until a dry mass results. 2078. Iodide of Magnesium. — Mgl 2 — This Salt may be made by dis- solving Magnesia to saturation in Hydriodic Acid, concentrating and crystal- lizing. 2079. Lactate of Magnesium. — Mg2C3H5O3.3H.3O. — This may be made by dissolving separately, in hot water, 6 parts of Lactate of Calcium and 5 parts Sulphate of Magnesium, mixing the solutions, filtering, evaporat- ing the filtrate, and crystallizing. 2080. Phosphate of Magnesium.— MgHP0 4 .6H 2 0. — This Salt may be made by mixing concentrated solutions of Sulphate of Magnesium and Phos- MALTUM — MALT. 603 phate of Sodium, allowing to stand some time, and collecting the crystals which form. 2081. Sulphate of Magnesium, Dried. — MgS0 4 — This is prepared by- heating Sulphate of Magnesium until it has lost one-third of its weight, then sifting it. 2082. Tartrate of Magnesium. — This maybe prepared by saturating a solution of Tartaric Acid with Carbonate of Magnesium, and evaporating by gentle heat to dryness. 2083. Magnesium Aperient or Seltzer Aperient. — Several Magnesian or Seltzer Aperients have had a large sale as proprietary medicines. The following formulae make preparations similar to those most popular: Sulphate of Magnesium 1 pound av., dry it by gradually increasing heat until it has lost one third of its weight ; then add Tartaric Acid, dried and powdered, 10 ounces av., Magnesia (calcined) 8 ounces av., White Sugar, 24 ounces av., Bicarbonate of Sodium, dried and powdered, 8 ounces av., and mix them all well together and pass through a sieve. Carbonate of Magnesium 1 pound, Bicarbonate of Sodium 1 pound, Rochelle Salts 2 pounds, Tartaric Acid 2 pounds. Mix them intimately. MALTUM — MALT. Grain, such as barley, oats, rye, maize, etc., in which a por- tion of the starch has become converted into sugar by malting is called malt. Barley and rye are the cereals usually employed for making malt, but other grains are sometimes used. The process of malting in brief consists in macerating the grain with just sufficient water to cover it, for 24 to 48 hours, during which time the water is mostly absorbed. The superfluous water is then drained off and the grain is deposited in heaps on the floor, where it is allowed to stand for 24 to 26 hours, dur- ing which time partial germination takes place, with a rise of temperature of about io° F. It is then spread thickly on the floor and repeatedly turned with wooden shovels for some time. When the grain has germinated sufficiently (which it requires experience to determine) it is thrown into a kiln and kiln-dried until the water has evaporated and it is gradually heated to about 150° F. As thus prepared it constitutes the Malt used by brewers. Tin- changes that occur in barley are 604 MALTUM — MALT. shown grains : by the followin g table. They are similar in other Composition of Barley. Composition of Malt. 55 32 5 3 4 1 56 15 15 100 IOO The chief changes that occur, therefore, are the transforma- tion of the hordeine (a form of starch peculiar to barley) into starch, sugar, and gum. 2084. Extract of Malt. The process of making Extract of Malt has previously been referred to (1038), the changes consisting in the conversion of starch, by the action of diastase, aided by heat, first into dex- trin and then into grape sugar. It is a thick syrup similar to glucose. The value of Extract of Malt, aside from its nutritive value as food, depends upon the quantity of Diastase which it con- tains, and which acts in the same manner as the Ptyalin of saliva to digest starch, one part being sufficient to dissolve 2,000 parts of starch. This Diastase is a ferment peculiar to the germination of grains and seeds, and is developed in the process of malting, its action of converting starch into sugar being cut short by the drying of the germinating grain. In making Extract of Malt great care must be exercised to preserve the excess of Diastase for the reasons above stated. The coarsely-ground Malt is first dampened with water heated to about 150 F., then firmly packed in the water-bath perco- lator, which is surrounded with water at about the same tem- perature. It is then covered with water heated to about 150 F. and allowed to stand for two hours, the heat being main- tained at the same temperature. The percolation is then begun and water, heated to the specified temperature, added to the Malt until the percolate has no longer a perceptibly MALTUM — MALT. 605 sweet taste. As the percolate is received it must be at once placed in the evaporating apparatus, which should be a water- bath, by which the heat maybe maintained at about 150 F., and the evaporation is to be conducted at that temperature until the product is concentrated to a thick syrup of 36 Bawne, or of which a pint will weigh 1^ pound av. As thus prepared Extract of Malt contains all its valuable properties unimpaired, and may be used as the basis for any of the vari- ous combinations which are called for. Uses. — Extract of Malt is a valuable aid to digestion of amylaceous food, and is in itself a nutritive and tonic. It is given in doses of a tablespoonful or more. Maltine. — Maltine is a proprietary Malt Extract, made by the Maltine Manufacturing Co., Yonkers, on the Hudson. It is claimed to be made of malted barley, wheat, and oats, equal parts, in the same general manner as has been described for making Extract of Malt. It is used for the same purposes and in the same manner as the foregoing. The formulas which are given for Malt Extract combinations apply to Maltine as well. 2085. Liquid Malt Extract. The thick Extracts of Malt which have previously been described are inconvenient for some forms of medication, a more limpid extract being much more desirable. In the thick Malt Extracts, also, a great portion of the Diastase has been required to convert the starchy matters into sugar, the excess, which was not required for that purpose, only being available. In the Liquid Malt Extracts it is aimed to retain the diastase and valuable extractive matter of the Malt without the con- version of its starch into sugar (as that only serves as a food which may be more cheaply supplied from other sources), and a consequent saving of Diastase. The following formula is designed to secure this result : Barley Malt, coarsely ground, ... 2 pounds av. Hops (new crop), coarsely ground, . . 2 ounces av. Alcohol, 2 pints. Water, a sufficient quantity. g06 MALTUM — MALT. Mix the Alcohol with 4 pints of Water, and, having mixed the Malt and the Hops together, moisten them with the liquid and pack firm in the water-bath percolator, and pour upon them the remainder of the liquid. Allow to stand 24 hours, then heat moderately, and, after one hour, begin to percolate and continue until the percolate will no longer drop, then add Water to the drugs in the percolator and continue the perco- lation until 4 pints have been obtained, which reserve ; con- tinue the percolation with Water until the drugs are exhausted, evaporate the last portion of the percolate by open evapora- tion to 4 fl. ounces. Distil the Alcohol from the reserved por- tion by the heat of a water-bath not exceeding 150 F., and when 2 pints have been recovered continue the evaporation on a water-bath, at the specified heat, until the liquid is reduced to 24 fl.ounces. To this add the reserved portion and 8 fl. ounces of Alcohol and filter clear. This makes a Fluid Extract of Malt in which all the valua- ble properties of Malt are retained. It is much stronger than most of the preparations put up as Liquid Malt Extract, and may be reduced for general sale by adding to it 3 or 4 parts of Water, with just sufficient Alcohol to insure its keeping. Uses.— It is used for the same purposes as other Malt Extracts and given in doses of a dessertspoonful or more. The diluted liquid may be given in doses of a wineglassful. Liquid Malt Extract may be used in any of the combinations for which formulae are given instead of Malt Extract, if desired. 2086. Malt Extract with Hops. Malt Extract l P lflt ' Fluid Extract of Hops # fl.ounce. Rub the fiuid Extract in a mortar first with a small portion of the Malt Extract and then with the remainder. It may also be made by steeping 1 part of hops in the percolate from 32 parts of malt during the process of condensation. This is called by some manufacturers Extract of Meat (plain). It is more desirable for dispensing and taking than simple Extract of Malt on account of the hop bitter, but it should not be used in combinations unless so directed. The dose is a dessertspoonful to a tablespoonful. 607 2087. Malt Extract with Alteratives. Bromide of Calcium, 160 grains. Iodide of Potassium, 160 grains. Bromide of Sodium 96 grains. Water, hot, 1 flounces. Malt Extract, 15 fl. ounces. Dissolve the Salts in the hot water and mix thoroughly with the Malt Ex- tract. The dose is a tablespoonful containing 13 grains of the Alterative Salts. 2088. Malt Extract with Beef and Iron. Liebig's Extract of Meat y 2 ounce av. Water, 1 fl. ounce. Malt Extract, 15 fl. ounces. Rub the Extract of Meat with the water and mix thoroughly with the Malt Extract. Dose, a tablespoonful to a wineglassful. 2089. Malt Extract with Cod Liver Oil Combinations. The formula for Cod Liver Oil with Extract of Malt is given (878), and consists simply in rubbing 8 fl. ounces of Cod Liver Oil with 8 fl. ounces of Malt Extract, and adding 20 minims Oil of Wintergreen, and 5 minims Oil of Bitter Almonds for flavoring. A great variety of medicines may be com- bined with this base, the following being the principal combinations known in the market. 2090. Malt Extract with Cod Liver Oil and Dialysed Iron. — Add 320 minims of Dialysed Iron to a pint of Malt Extract with Cod Liver Oil. The dose is a tablespoonful containing 10 minims Dialysed Iron. 2091. Malt Extract with Cod Liver Oil and Iodide of Iron. — Dissolve 32 grains Tasteless Iodide of Iron (Creuse's), in y 2 ounce hot Water and mix thoroughly with a pint of Malt Extract with Cod Liver Oil. The dose is a tablespoonful containing 1 grain Tasteless Iodide of Iron. 2092. Malt Extract with Cod Liver Oil and Pepsin. — Saccharated Pepsin, 128 grains, rubbed to a fine powder in a mortar, then with a portion of the Cod Liver Oil and Malt, and then with the remainder. Dose, a table- spoonful containing 4 grains of Pepsin. 2093. Malt Extract with Cod Liver Oil and Pancreatin. — Saccharated I'ancreatin, 128 grains, rubbed to a fine powder in a mortar, then with a por- tion of the Cod Liver Oil and Malt, and then with the remainder. Dose, a tablespoonful containing 4 grains Pancreatin. 608 MA LIT M — MALT. 2094. Malt Extract with Cod Liver Oil, Pepsin and Pancreatin. — Saccharated Pepsin, 1 28 grains, Saccharated Pancreatin, 1 28 grains, mixed with a pint of Cod Liver Oil and Malt, the same as the preceding. The dose is a tablespoonful containing 1 grain each Pepsin and Pancreatin. 2095. Malt Extract with Cod Liver Oil and Hypophosphites. — Hypo- phosphite of Calcium, 64 grains, Hypophosphite of Sodium, 48 grains, Hypo- phosphite of Potassium, 32 grains, Glycerin, 1 fl.ounce, hot Water, 1 flounce. Malt with Cod Liver Oil, 14 flounces. Rub the Hypophosphites to a fine powder and dissolve as nearly as possible in the hot Water and Glycerin, then rub thoroughly with the Malt and Cod Liver Oil. Dose, a tablespoonful containing about 4^ grains of the Hypophosphites. 2096. Malt Extract with Cod Liver Oil and Phosphorus. — Thomp- son's Solution of Phosphorus, 1 fl.ounce, mixed thoroughly by rubbing first with a small portion of Malt Extract with Cod Liver Oil sufficient to make a pint. Dose, a tablespoonful, containing about T 4„ grain of Phosphorus. 2097. Malt Extract with Cod Liver Oil, Phosphorus, Iron and Nux Vomica. — Add to the above preparation 1 drachm Tincture of Nux Vomica, and 1 drachm Solution of Phosphate or Iron. 2098. Malt Extract with Cod Liver Oil and Phosphates.— Concentrated Solution of Phosphates Compound (1938), ]/ 2 fl.ounce, Cod Liver Oil and Malt, 1 pint. Mix them thoroughly by rubbing together in a mortar. 2099. Extract of Malt with Iron. — Extract of Malt may be combined with most any of the strong Solutions or Soluble Salts of Iron. 2100. Extract of Malt with Citrate of Iron. — Dissolve 64 grains of Citrate of Iron and Ammonium in half an ounce of Hot Water and mix with a pint of Extract of Malt. Dose, a tablespoonful, containing 2 grains of the Iron Salt. 2101. Extract of Malt with Dialysed Iron. — Mix 320 minims Solution Dialysed Iron with a pint of Malt Extract. Dose, a tablespoonful, containing 10 minims Dialysed Iron. 2102. Extract of Malt with Iodide of Iron. — Dissolve 64 grains Taste- less Iodide of Iron (Creuse's) in half fl.ounce Warm Water and mix with a pint of Extract of Malt. Dose, a tablespoonful, containing 2 grains of the Iron Salt. 2103. Extract of Malt with Phosphate of Iron.— Dissolve 64 grains Phosphate of Iron in scales (1880) in half an ounce of Hot Water and mix with a pint of Malt Extract. The dose, a tablespoonful, contains 2 grains of the Iron Salt. 2104. Extract of Malt with Tincture of Iron.— Tasteless Tincture of Iron (1923) half fl.ounce Extract of Malt a pint; mix them well together. Combinations may also be made by mixing equal measures of Malt Extract and Elixir Gentian with Tincture Chloride of Iron. 609 2105. Extract of Malt with Phosphate of Iron and Quinine. — Malt Extract, 8 fl. ounces, Elixir Iron and Quinine, 8 fl. ounces; mix them well together. Citrate of Iron and Quinine with Malt Extract may be made by adding 2 fl. ounces of Solution Citrate of Iron and Quinine to 14 fl. ounces of Extract of Malt. 2106. Extract of Malt with Phosphate of Iron, Quinine and Strych- nine. — Malt Extract, 8 fl.ounces, Elixir Iron, Quinine and Strychnine, 8 fl.ounces. Mix them well together. Citrate of Iron, Quinine and Strychnine with Malt Extract, may be made by adding 2 fl.ounces Solution Citrate of Iron and Quinine and 1 fl.drachm of Solution of Strychnine to 14 fl.ounces of Malt Extract. 2107. Extract of Malt with Hypophosphites. Hypophosphite of Calcium 64 grains. Hypophosphite of Sodium 48 grains. Hypophosphite of Potassium 32 grains. Glycerin 1 fl. ounce. Hot Water 1 fl.ounce. Extract of Malt, 14 fl.ounces. Rub the Hypophosphites to a very fine powder in a mortar, dissolve them as nearly as possible in the Hot Water and Glycerin, and mix them with the Malt Extract. The dose is a tablespoonful, containing 4^ grains of the mixed Hypophosphites. 2108. Extract of Malt with Lactopeptine. Lactopeptine 128 grains. Hydrochloric Acid, diluted 1 fl.drachm. Glycerin 1 fl.ounce. Water 1 fl.ounce. Malt Extract 14 fl.ounces. Rub the Lactopeptine with the Glycerin and Water, add the Acid, and macerate in a warm place for 12 hours, then mix with the Malt Extract. The combinations of Lactopeptine with Malt Extract may be made in the same manner as those of Pepsin. 2109. Extract of Malt with Lactophosphates. Solution Lactophosphate of Calcium '.. fl.ounce. Solution Lactophosphate of Iron '4 fl.ounce. Malt Extract 1 pint. Mix them thoroughly. A tablespoonful contains 5 grains of the Lacto- phosphates. A variety of combinations of Extract of Mall and I actophos- 610 MALTUM — MALT. phates, and Calisaya, Gentian, etc., may be made by mixing equal parts of Malt Extract with Lactophosphates, and Elixirs of Calisaya, Gentian, etc., as desired. 21 io. Extract of Malt with Pepsin. Saccharated Pepsin 128 grains. Hydrochloric Acid, diluted 1 fi.drachm. Glycerin, 1 fl.ounce. Water 1 fl.ounce. Malt Extract, 14 fl.ounces. Rub the Pepsin with the Glycerin and Water, add the Acid and macerate in a warm place for 1 2 hours, then mix with the Malt Extract. A tablespoon- ful contains 4 grains Pepsin. 2111. Extract of Malt with Pepsin and Bismuth. — Solution of Bis- muth (1873) ]/ 2 fl.ounce, Extract of Malt with Pepsin 1 pint. Rub the Solu- tion first with a small portion of the Extract of Malt and Pepsin, and then with the remainder. A dessertspoonful, the usual dose, contains 2 grains each Pepsin and Bismuth. 21 12. Extract of Malt with Pepsin, Bismuth, and Strychnine. — Solution of Bismuth (1873) y* fl.ounce, Solution of Strychnine (1942) 1 fi.drachm, Extract of Malt with Pepsin 1 pint. Rub the Solutions first with a small portion of the Extract of Malt and Pepsin, and then with the remain- der. A dessertspoonful, the usual dose, contains 2 grains each Pepsin and Bismuth and -fe grain Strychnine. 21 13. Extract of Malt with Pepsin and Iron.— Solution of Citrate or Phosphate of Iron yi fl.ounce, Extract of Malt with Pepsin 1 pint. Mix the Solution with the Extract. Other solutions or salts of Iron may be combined, as desired, with Extract of Malt with Pepsin. The usual dose is a table- spoonful, containing 4 grains of the Iron salt and 4 grains of Pepsin. 21 14. Extract of Malt with Pepsin and Pancreatin. — Saccharated Pep- sin 128 grains, Saccharated Pancreatin 128 grains, Extract of Malt 1 pint. Rub the powders first with a small portion of the Extract, and then with the remainder. A dessertspoonful, the usual dose, contains 2 grains each Pepsin and Pancreatin. 21 15. Malt Extract with Peptones. — This is made by digesting finely chopped beef 2 ounces av., at about ioo° F., in a solution made of Scale Pepsin 30 grains, Hydrochloric Acid, diluted, 2 fl.drachms, Water 1 fl.ounce, Glycerin 1 fl.ounce, until the beef is reduced to a semi-fluid state, requiring about 6 or 7 hours. This is then mixed with sufficient Malt Extract to make a pint. MALTUM — MALT. 611 2116. Malt Extract with Phosphates. Concentrated Solution of Phosphates, 1 fl.ounce. Malt Extract 15 flounces. Mix them thoroughly. Dose, a dessertspoonful to a tablespoonful. A variety of combinations of this preparation with Calisaya, Gentian, etc., may be made if desired. 21 17. Malt Extract with Cascara Sagrada. — This may be made by mixing 1 fl.ounce of Fluid Extract Cascara Sagrada with 15 fl. ounces of Malt Extract. It is best combined with Liquid Malt Extract. It is a valuable laxa- tive, in doses of a tablespoonful or more. 21 18. Malt Extract with Viburnium. — Mix 1 fl.ounce Fluid Extract of Black Haw with 15 fl. ounces Liquid Extract of Malt. Dose, a tablespoonful as a tonic for female difficulties, etc. 2119. Malt Extract with Wafer Ash. — Mix 1 fl.ounce Fluid Extract Ptelea or Wafer Ash Bark with i 5 fl. ounces Malt Extract. Used for a tonic, dyspepsia, etc. Dose, a dessertspoonful or more. Many other combinations of Malt Extract or Liquid Malt Extract with fluid extracts of tonics, laxa- tives, etc., may be used to advantage. 2120. Malt Extract with Yerba Santa.— Mix 1 fl.ounce Fluid Extract Verba Santa with 15 fl.ounces of Malt Extract. As a carrier for Quinine and other bitter medicines this preparation cannot be excelled. The following combinations of Malt Extract have a popular sale as proprietary medicines, and may be readily and profitably put up by druggists : 2121. Malt Bitters. Bitter Orange Peel, 4 ounces av. Wahoo Bark 2 ounces av. Cardamom Seeds 1 ounce. iraon Bark 1 ounce. Good Whisky 3 pints. Water zyi pints. Liquid Malt Extract 3 pints. Grind the drugs to a coarse powder and percolate in the water-bath per- colator with the mixed Whisky and Water, then add the Liquid Malt Extract to the percolate, and filter or strain. The dose is a tablespoonful to a wine- glassful. C12 MALTUM — MALT. 2122. Malt and Tar Cough Syrup. Oil of Tar ^ fl.ounce. Oil of Wintergreen, . . . 15 minims. Oil of Peppermint io minims. Oil of Sassafras 10 minims. Oil of Anise 15 minims. Tincture of Tolu 2 fl.ounces. Carbonate of Magnesium, 2 ounces av. Water y/ 2 pints. Alcohol l / 2 pint. Fluid Extract Lobelia, 1 fl.ounce. Fluid Extract Bloodroot, l / 2 fl.ounce. Tincture of Opium, 6 fl.ounces. Chloroform 2 fl.drachms. Chloride of Ammonium 2 ounces av. Tartar Emetic 30 grains. Malt Extract, 4 pints. Mix the Oils with the Tincture of Tolu, and rub together with the Carbon- ate of Magnesium in a mortar. Mix the Alcohol with the Water, and tritu- rate with the mixture in the mortar ; then set aside for a few hours and filter. Dissolve the Tartar Emetic and Chloride of Ammonium in the filtrate. Mix the fluid extracts Tincture of Opium and Chloroform with the Malt Extract by agitation ; then add the filtrate in which the salts have been dissolved and shake them well together. This is a very efficient cough remedy. Other ingredients may be added if desired. The dose is from a teaspoon ful to a dessertspoonful. 2123. Malt Tonic. Sulphate of Quinine 60 grains. Sulphate of Cinchonidine, 120 grains. Compound Tincture of Cardamom 4 fl.ounces. Good Whisky 4 pints. Water 2 pints. Liquid Malt Extract 3 pints. Mix the Whisky, Water, and Compound Tincture of Cardamom and dis- solve the Alkaloidal salts in the mixture. After standing a few hours add the Malt Extract and strain or filter. Many other ingredients may be added to this preparation if desired, as Tincture or Fluid Extract of Hops, say 2 ounces, for Mai (-Hop Ionic, etc. The dose is a dessertspoonful to a tablespoonful. MANGANESE. 613 2124. Malt Cordial, or Malt-Wine Cordial. This may be made the same as the foregoing, only using Wine in place of the Whisky, or as follows : Sulphate of Quinine, 40 grains. Sulphate of Cinchonidine 80 grains. Soluble Elixir Flavoring 4 fl. ounces. Sherry or other Wine, 3 pints. Water 1% pint. Alcohol Yz pint. .Malt Extract 3 pints. Mix the Wine, Water, and Alcohol and dissolve the Alkaloidal salts in the mixture, add the Elixir flavoring, let stand a few hours, then add the Malt Extract and strain or filter. This is also known as Malt Wine, and many combinations with it may be made. MANGANESE. Symbol, Mn ; Atomic Weight, 54; Sp. gr., 7.13. Manganese is a very hard, brittle metal, found quite abund- ant in the form of black oxide. It is classed chemically with iron and chromium, its salts very much resembling those of iron. Metallic Manganese is seldom seen except in the chem- ist's laboratory; its affinity for oxygen is so great that when powdered it decomposes water without the aid of heat, and must be preserved in naphtha. It forms compounds with the non-metallic elements, and unites with hydrogen and oxygen, forming Manganic Acid(H 2 Mn O^), which is only known in its combinations with bases called Manganates. With Oxygen it forms definitely five compounds, and two more are supposed to exist. The Binoxide of Man- ganese is much employed as a source of Oxygen for manufac- turing purposes, as in the production of chlorine for bleaching purposes, the melting of glass with the oxyhydrogen jet, etc. In pharmacy it is employed for the production of chlorine, permanganate of potassium, and peroxide of hydrogen. A 014 MANGANESE. few of the Manganese salts are employed in medicine as alteratives and tonics. The following- are the official salts of Manganese : 2125. Mangani Oxidum Nigrum. Black Oxide of Manganese — Dioxide of Manganese. MnO s This is described in the U. S. P. as native crude Binoxide of Manganese, containing at least 66 per cent, of the pure Oxide. The Br. P. gives it the name Manganesii Oxidum Nigrum. Uses. — It is the commercial basis of the Manganese salts, and is extensively used for obtaining oxygen for chemical and industrial purposes. As found in the market it varies consid- erably as regards it purity, and those who use it largely for industrial purposes buy it only upon assay. 2126. Mangani Sulphas. Sulphate of Ma?iganese. MnS0 4 .4H 2 0. This may be prepared by the process suggested by Pro. Diehle, which consists in heating together to redness in a crucible Manganese dioxide and charcoal, treating the residue with Sulphuric Acid and again heating to redness, then dis- solving the residue in water, filtering the solution and crystallizing. Uses. — This salt is used in making some other preparations of Manganese, and is sometimes given in doses of 5 to 15 grains as a tonic. Other Salts of Manganese. The two foregoing are all the salts of Manganese official in the U. S. P. The Permanganate of Potassium is the most MANGANESE. 615 important Manganese compound medicinally, but that is included in the Potassium salts. Quite a number of the other Manganese salts have their uses in pharmacy and medicine, the most important ones being noted below : 2127. Acetate of Manganese— Mn(C 2 H 3 2 ) 2 . — This salt may be most conveniently made by neutralizing Acetic Acid with Carbonate of Manganese, concentrating the solution by evaporation and crystallizing. 2128. Arseniate of Manganese— MnHAs0 4 . — By neutralizing a Solu- tion of Arsenic Acid with freshly precipitated Carbonate of Manganese, concentrating and crystallizing. 2129. Benzoate of Manganese. — By adding to a Solution of Benzoic Acid Carbonate of Manganese until no more will be combined. 2130. Carbonate of Manganese — MnCO s . — This is most conveniently- made by adding a Solution of Sulphate of Manganese to a Solution of Car- bonate of Potassium or Sodium, washing the precipitate and drying. 2131. Chloride of Manganese — MnCl 2 . — By dissolving Dioxide of Manganese in Hydrochloric Acid, purifying from Iron salts, etc., evaporating and crystallizing. 2132. Citrate of Manganese. — By dissolving Carbonate of Manganese in a strong Solution of Citric Acid, concentrating and crystallizing. 2133. Hypophosphite of Manganese. — By dissolving Carbonate of Manganese in Hypophosphorous Acid, and crystallizing, or by decomposing a Solution of Sulphate of Manganese with a strong Solution of Hypophosphite of Calcium, filtering, and concentrating the solution. 2134. Iodide of Manganese. — By dissolving Carbonate of Manganese in Hydriodic Acid, concentrating and crystallizing in vacuo. 2135. Oxides of Manganese. — Besides the official Dioxide of Mangan- ese, Mn0 2 , which is black, there exists the Monoxide, MnO, light green, the Sesquioxide, M11J),, dark brown, the Magnetic Oxide, Mn 3 4 , red, and Permanganic Oxide, Mn 2 7 , a dark brown liquid. 2136. Phosphate of Manganese — MnHP0 4 .6H 2 0. — This is most con- veniently made by precipitating a Solution of Sulphate of Manganese by adding it to a Solution of Phosphate of Sodium, washing the precipitate and drying. 2137. Tartrate of Manganese — MnC 4 H 4 O .— By adding freshly pre- cipitated Carbonate of Manganese to a Solution of Tartaric Acid, concentrat- ing and crystallizing. Manganic Acid, lUInu,, is only known by its salts, which are called Manganalcs. /'crmaiign/iit Acid, 1 1 MnO.,, is obtained by cautiously dis- tilling Permanganate of Potassium and Sulphuric Acid. It is the acid base of the Permanganate salts. 616 MASS. K— MASSES. M ASS^E — MASSES. Under this title the U. S- P. gives the formulae for three preparations, which are made and kept in the form of a pilular mass, and are frequently sold or dispensed in this form, but are also designed to be made up into pills, or to be mixed with other substances for making pills. Under the title Pilulae in the Br. P. quite a number of masses are included, see PlLUL^E. The U. S. official formulas are as follows : 2138. Massa Copaibae. Mass of Copaibce — Pilnhu Copaiba? . Copaiba 94 parts or 1 ounce av., Magnesia (recently pre- pared) 6 parts or 28 grains. Mix them intimately and set aside until it concretes into a pilular mass. 2139. Massa Ferri Carbonatis. Mass of Carbonate of Iron — Vallefs Mass — Pilala? Ferri Carbonatis. Sulphate of Iron, . . . Carbonate of Sodium, . Clarified Honey, . . . Sugar, in coarse powder, Distilled Water, ) Syrup, ! Dissolve the Iron Salt and Sodium Salt separately, each in 200 parts or a pint of boiling Distilled Water, and, having added 25 parts or 3 fl. drachms of Syrup to the solution of Iron Salt, filter both solutions. Mix them when cold in a bottle just large enough to hold both solutions, and stop the bottle tightly and set aside so that the Carbonate of Iron may subside. Pour off the supernatant liquid, and having mixed Syrup and Distilled Water in the proportion of one part or 100 parts or 2 ounces av. 1 10 parts or 2}i ounces av. 38 parts or Y^ ounce av. 25 parts or y 2 ounce av. each a sufficient quantity. MASS.E — MASSES. 617 \y 2 fl. drachm of Syrup to 16 parts or 4 fl. ounces of water. Wash the precipitate until the washings no longer have a saline taste. Drain the precipitate on a flannel cloth and ex- press as much of the water as possible. Lastly, mix the pre- cipitate immediately with the Honey and Sugar, and by means of a water-bath evaporate the mixture, stirring constantly until it is reduced to 100 parts or two ounces av. The Br. Pilula Ferri Carbonatis is made with Saccharated Carbonate of Iron, Br., 1 ounce, Confection of Rose y± ounce. The German Pilulce Ferri Carbonici is made with Sulphate of Iron 50 parts, Bicarbonate of Sodium 35 parts, Powdered Sugar 8 parts, Clarified Honey 26 parts, Water, etc., in the same manner as by the U. S. formula, to make 40 parts. 2140. Massa Hydrargyri. Mass of Mercury — Blue Mass— Blue Pill. Mercury, 33 parts or 578 grains. Glycyrrhiza, in N0.60 Powder, 5 parts or 58 grains. Althaea, in No. 60 Powder, 25 parts or 1 ounce av. Glycerin, 3 parts or 45 minims. Honey of Rose, .... 34 parts or 1 x /% fl. ounce. Triturate the Mercury with the Honey of Rose and Glycerin until it is extinguished. Then gradually add the Glycyrrhiza and Althaea, and continue the trituration until globules of Mercury cease to be visible under a lens magnifying 10 diam- eters. The extinguishment of the Mercury may be hastened by adding to the Honey of Rose a few drops of Tincture of Tolu or Benzoin occasionally. The Br. formula under the title Pilula Hydrargyri or Mer- curial Pill is Mercury 2 ounces av., Confection of Rose 3 ounces av., Liquorice Root in fine power 1 ounce av. The Mercury is first rubbed with the Confection, then with the Liquorice. Blue Mass is one of the articles most frequently called for, but it is seldom made by druggists, being supplied by manu- facturing pharmacists, who have better facilities for pre- paring it. 618 MELITA — HONEYS. MELITA — HONEYS. Honey is a saccharine secretion deposited by the Honey Bee, Apis Mcllifica, in honey comb. In pharmacy strained or drawn Honey only is employed as a basis of Honey prep- arations and sold or dispensed in medicine. The following preparations of Honey are official. They are thick, syrupy preparations, used chiefly for their local effect or as carriers for medicinal substances. 2141. Mel Despumatum. U. S. Clarified Honey. Honey, a convenient quantity. Heat by means of a water- bath, remove the scum, and strain. The Br. and German Pharmacopoeias, under the title of Mel Depuratiun, direct similar methods of preparing it. This is used for making confections, oxymel, etc. 2142. Mel Boracis. Br. Borax Honey. Borax, in fine powder, ... 60 grains or 2 parts. Glycerin, 30 grains or 1 part. Clarified Honey, 480 grains or 16 parts. Mix them. This is used for cankered mouth and throat. 2143. Mel Rosae. U. S. Honey of Rose. Red Rose, in No. 40 powder, 8 parts or 2 ounces av. Clarified Honey, .... 92 parts or 23 ounces av. Diluted Alcohol, a sufficient quantity. Moisten the powder with 2 parts or y 2 fi. ounce of diluted Alcohol, pack it firmly in a conical glass percolator and gradu- ally pour diluted Alcohol upon it until 33 parts or 8 fi. ounces MELITA — HONEYS. METHYL. 619 of percolate are obtained. Reserve the first 3 parts or 6 fl. drachms of the percolate, evaporate the remainder by means of a water-bath to 5 parts or 10 fl. drachms, add the reserved portion, and mix the whole with the clarified Honey. The German formula produces a similar preparation. This is used in making several washes and confections. The following Oxymels, official in the Br. P., may quite properly be included under this heading: 2144. Oxymel. Br. Clarified Honey, 40 ounces or 8 parts. Acetic Acid, 5 fl. ounces or 1 fl.part. Distilled Water, 5 fl. ounces or 1 fl.part. Liquefy the Honey by heat and mix with the Acetic Acid and Water. The dose is 1 to 2 fl. drachms for coughs, etc. 2145. Oxymel Scillae. Br. Oxymel of Squill. Vinegar of Squill 1 pint or 5 fl. parts. Clarified Honey, 2 pounds or 8 parts. Mix and evaporate by a water-bath until the product, when cold, shall have a specific gravity of 1.32. This is used for coughs, in doses of ^ to a teaspoonful. METHYL. CH 8 . Methyl is the radical of the Methyl series of compounds of which Methylic or Wood Alcohol is the hydrate. It forms, with other bodies, a large number of compounds highly impor- tant in chemistry and pharmacy, similar in characteristics to 620 \iisrrk.K — mixtures. the compounds of Amyl, Ethyl and other radicals of the Alco- hol series, see page 85. The most important combination of Methyl is its hydrate, Methylic or Wood Alcohol, which is obtained by distillation from carbonaceous substances and is hence called Carbonol. It is the commercial basis of the Methyl products, and has already been described, page 95. The other Methyl salts are but little used in pharmacy, the Acetate, Chloride and Iodide being the most important. Methyl salts form valuable com- binations with Aniline, producing some of the most brilliant colors, and Oil of Wintergreen is chemically Salicilate of Methyl. MISTUR^ MIXTURES. The term Mixture is applied in Pharmacy to aqueous liquid preparations which contain insoluble substances suspended or precipitated, and are intended for internal use or administra- tion. In a popular sense the name Mixture is applied to a great variety of preparations, many of which are emulsions, solutions, syrups, tinctures, etc. Under this heading the Mix- tures official in the U. S. and Br. Pharmacopoeias will first be given and then the more important unofficial Mixtures which are not more naturally included under other headings. See, also, Proprietary Medicines, the Standard Remedies, etc. 2146. Mistura Ammoniaci. Ammoniac Mixture. U. S. — Ammouiacum Mixture. Br. Ammoniac, 4 parts or 18 grains. Water, 100 parts or 1 fl. ounce. Rub the Ammoniac with the Water gradually added until they are thoroughly mixed, and strain. The Br. formula is about the same, being ]/^ ounce av. to 8 fl. ounces of Water. This is used for coughs, etc., in doses of y 2 to a fl. ounce. MISTURA — MIXTURES. 621 2147. Mistura Amygdalae. Almond Mixture. The U. S. formula is : Sweet Almonds 6 parts or 240 grains. Acacia, in fine powder, . . 1 part or 40 grains. Sugar, 3 parts or 120 grains. Distilled Water, .... 100 parts or 9 fl. ounces. Having blanched the Almonds, add the Acacia and Sugar and beat them in a mortar until thoroughly mixed ; then rub the mixture with the distilled Water, gradually added, and strain. The Br. formula is compound powder of Almonds 2 ounces, distilled Water 16 fl. ounces, rubbed together and strained. This is a bland mixture, used for irritable stomach, coughs, etc. Dose I to 2 fl. ounces. 2148. Mistura Asafoetidae. U. S. Asafctida Mixture. Asafetida, 4 parts or 18 grains. Water 100 parts or 1 fl. ounce. Rub the Asafetida with the Water, gradually added, until they are thoroughly mixed, and strain. The dose is a dessertspoonful to a tablespoonful, as an anti- spasmodic, for worms, etc. 2149. Mistura Chloroformi. U. S. Chloroform Mixture. Purified Chloroform, . . . 8 parts or 4 11. drachms. Camphor, 2 parts or 96 grains. Fresh Yolk of Egg, ... 10 parts or 1 fl.ounce. Water 80 parts or 8 tl. ounces. Rub the Yolk of Egg in a mortar, first by itself, then with the Camphor, previously dissolved in the Chloroform, and, 622 M ISTUR/E — MIXTURES. lastly, with the Water, gradually added, so as to make a uni- form mixture. This is really an emulsion of Chloroform and Camphor, mak- ing a very convenient manner of exhibiting them. The dose is a teaspoonful to a dessertspoonful. 2150. Mistura Creasoti. Br. Creasote Mixture. Creasote, Glacial Acetic Acid, Spirit of Juniper, Syrup, .... Distilled Water, . 1 5 minims or 1 fl.part. 15 minims or 1 fl.part. 30 minims or 2 fl. parts. 1 fl. ounce or 32 fl. parts. 15 fl. ounces or 480 fl. parts. Mix the Creasote with the Acetic Acid, gradually add the Water, and, lastly, the Syrup and Spirit. Dose, 1 to 2 fl. ounces. 2151. Mistura Cretae. Chalk Mixture. The U. S. formula directs : Compound Chalk Powder, . 20 parts or 240 grains. Cinnamon Water 40 parts or 1 fl. ounce. Water 40 parts or 1 fl. ounce. Rub the Powder with the Cinnamon W T ater, and Water gradually added, until they are thoroughly mixed. This preparation as thus prepared will not keep for any great length of time, and it is suggested to use, instead of 1 fl. ounce of Water, only x / 2 ounce, and y 2 ounce Alcohol, making a permanent preparation. The Br. formula is : Prepared Chalk %. ounce av., powdered Acacia % ounce av., Syrup y 2 fl. ounce, Cinnamon Water jy 2 fl. ounces. The dose of Chalk Mixture is 1 to 2 fl. ounces, as an antacid and for bowel complaints of children. MISTUR^E — MIXTURES. 623 2152. Mistura Ferri Aromatica. Br. Aromatic Mixture of Iron. Red Cinchona Bark, in powder, . . 1 ounce av. Columba Root, in coarse powder, . . y 2 ounce. Cloves, bruised, in coarse powder, . . y ounce. Fine Iron Wire, y 2 ounce. Compound Tincture of Cardamom, . 3 fl. ounces. Tincture of Orange Peel y 2 fl. ounce. Peppermint Water, a sufficient quantity. Macerate the drugs and the Iron with 12 fl. ounces of Pep- permint Water, in a closed vessel, for three days, agitating occasionally; then filter the liquid, adding as much Pepper- mint Water to the filtrate as will make the product measure \2y 2 fl. ounces ; to this add the tinctures, and preserve the mixture in a well-stopped bottle. Dose, 1 to 2 fl. ounces, as an iron tonic. 2153. Mistura Ferri Composita. Compound Iron Mixture — Griffith's Mixture. The U. S. formula is: Sulphate of Iron, in coarse powder, 6 parts or 24 grains. Myrrh, in small pieces, . . 18 parts or 72 grains. Sugar, 18 parts or 72 grains. Carbonate of Potassium, . . 8 parts or 32 grains. Spirit of Lavender 50 parts or y 2 fl. ounce. Rose Water 900 parts or 8 fl. ounces. Rub the Myrrh, Sugar and Carbonate of Potassium with the Rose Water, gradually added, then with the Lavender, and lastly with the Sulphate of Iron. Pour the mixture immedi- ately into a bottle, which should be well stopped. The Br. formula is Sulphate of Iron 25 grains, Myrrh, Sugar. each 60 grains. Carbonate of Potassium, 30 grains, Spirit of G24 MISTUR^E — MIXTURES. Nutmeg, 4 fl. drachms, Rose Water, g 1 /, fl. ounces, made in a similar manner. This is used as an iron tonic, especially for female com- plaints, amenorrhcea, etc. The dose is from I to 2 fl. ounces. 2154. Mistura Ferri et Ammonii Acetatis. U.S. Mixture of Acetate of Iron and Ammonium — Bashairi s Mixture. Tincture Chloride of Iron, . 2 parts or 3 fl. drachms. Diluted Acetic Acid, ... 3 parts or 4 fl. drachms. Solution of Acetate of Am- monium 20 parts or 3^ fl. ounces. Elixir of Orange (Simple Elixir), 10 parts or 1^ fl. ounce. Syrup, 15 parts or 2 fl. ounces. Water, 50 parts or 8 fl. ounces. To the Solution of Acetate of Ammonium, previously mixed with the Diluted Acetic Acid, add the Tincture of Chloride of Iron, and afterward the Elixir of Orange, Syrup and Water, and mix the whole thoroughly. The dose of this, as an aromatic iron tonic, is an ounce or more after meals. 2155. Mistura Glycyrrhizae Composita. U. S. Compound Mixture of GlycyrrJiiza — Brown Mixture. Pure Extract of Glycyrrhiza, 3 parts or ]/ 2 ounce av. Sugar 3 parts or x / 2 ounce av. Acacia, in fine powder, . . 3 parts or y 2 ounce av. Camphorated Tincture of Opium, 12 parts or 2 fl. ounces. Wine of Antimony, . . . 6 parts or 1 fl. ounce. Spirit of Nitrous Ether, . 3 parts or x / 2 fl. ounce. Water, 70 parts or 12 fl. ounces. Rub the Extract of Liquorice, Sugar, and Acacia, with the Water gradually added ; then add the other ingredients, and mix the whole thoroughly. MISTURjE — MIXTURES. 625 Brown Mixture Improved. — As made by the foregoing formula, this preparation always has quite a precipitate or sediment, and although this corre- sponds with the pharmaceutical idea of a mixture, it is quite undesirable for dispensing in this form. The following formula does away with this objec- tion chiefly : Glycyrrhizin Ammoniated 160 grains, Acacia in fine powder y 2 ounce av., Tincture of Opium 160 minims, Wine of Antimony I fl.ounce, Spirit of Nitrous Ether y* fl.ounce, Alcohol 2 fl.ounces, Warm Water suffi- cient to make a pint. Mix and dissolve. Uses. — Brown Mixture was formerly very much prescribed as a cough preparation, and is yet considerably used for that purpose, in doses of a tea- spoonful or more. 2156. Mistura Guaiaci. Br. Guaiacum Mixture. Guaiacum Resin, ... y 2 ounce av. or 1 part. Refined Sugar, ... y 2 ounce av. or 1 part. Gum Arabic, powdered, . y ounce av. or y part. Cinnamon Water, ... 20 fl.ounces or 40 fl. parts. Triturate the Guaiacum with the Sugar and the Gum, add- ing gradually the Cinnamon Water. Uses. — This is a favorite remedy for rheumatism, in doses of y 2 to 2 fl.ounces. 2157. Mistura Magnesii et Asafoetidae. U. S. Mixture of Magnesia and Asafetida — Dewee's Carminative. Carbonate of Magnesium, 5 parts or 260 grains. Tincture of Asafetida, . . 7 parts or 10 fl. drachms. Tincture of Opium, . . . 1 part or 75 minims. Sugar, 10 parts or 1^ ounce av. Distilled Water, sufficient to make 100 parts or a pint. Rub the Carbonate of Magnesium and Sugar in a mortar with the Tinctures, then add gradually enough distilled Water to make 100 parts or a pint. This favorite remedy is much used for children, in doses of a teaspoonful to a tablespoonful. 626 mistura — MIXTURES. 2158. Mistura Potassii Citratis. Mixture of Citrate of Potassium — Neutral Mixture. Fresh Lemon Juice, strained, 100 parts or 4 fl. ounces. Bicarbonate of Potassium, about 10 parts or 170 grains. Add the Bicarbonate of Potassium gradually to the Lemon Juice until it is neutralized. This should be freshly made when wanted for use. It is used chiefly as a refrigerant. 2159. Mistura Rhei et Sodae. U. S. Mixture of Rhubard and Soda. Bicarbonate of Sodium, . 30 parts or ]/ 2 ounce av. Fluid Extract of Rhubarb, 30 parts or 3 fl. drachms. Spirit of Peppermint, . . 30 parts or 5 fl. drachms. Water, sufficient to make 1000 parts or a pint. Dissolve the Bicarbonate of Sodium in 500 parts or half a pint of Water, add the Fluid Extract and Spirit and then enough Water to make 1000 parts or a pint. This is used as an antacid and laxative, in doses from y 2 to 2 fl. ounces. 2160. Mistura Scammonii. Br. Scammony Mixture. Scammony, in powder, ... 6 grains or I part. Milk, 2 fl. ounces or 146 parts. Triturate the Scammony with the Milk until a uniform emul- sion is obtained. This should be freshly made when wanted for use. The dose is from 1 to 3 fl. ounces, as a purgative. MISTURiE — MIXTURES. 627 2161. Mistura Sennas Composita. Br. Compound Mixture of Senna — Black Draught. Sulphate of Magnesium, 4 ounces av. or 4 parts. Liquid Extract of Liquor- ice, 1 ounce av. or 1 fl.part. Tincture of Senna, . Compound Tincture Cardamoms, . . . Infusion of Senna, Dissolve the Sulphate of 23/2 fl. ounces or 2.y 2 fl.parts. )f \y 2 fl. ounce or \y 2 fl.part. 15 fl. ounces or 15 fl.parts. Magnesium in the Infusion of Senna with the aid of a little heat, then add the Liquid Extract and the Tinctures. This is the familiar British Black Draught, quite similar to the U. S. and German Infusion of Senna Compound, but stronger. Uses. — This is used as a purgative, in doses of 1 to lyi fl. ounces, and as a laxative in smaller doses. 2162. Mistura Spiritus Vini Gallici. Br. Mixture of French Brandy. French Brandy, 4 fl. ounces. Cinnamon Water, 4 fl. ounces. The Yolks of two Eggs. Refined Sugar, y ounce. Rub the Yolks and the Sugar together, then add the Cinna- mon Water and the Spirit. Uses. — Although our British friends call this a pharmaceu- tical preparation, it is more familiarly known in this country ,-Nogg, but is somewhat improved by more Sugar. Other Mixtures. The foregoing official Mixtures are all that are recognized in the U. S. and Br. Pharmacopoeias, but a great many others 628 MISTUR.-E — MIXTURES. have been introduced by popular physicians as their favorite mixtures, and their formulae have been preserved, and are here repeated. Other formulas for Mixtures will be found under other headings: 2163. Brown-Sequard's Anti-Epileptic Mixture. — Bromide of Sodium 360 grains, Bromide of Potassium 360 grains, Bromide of Ammonium 360 grains, Iodide of Potassium 180 grains, Iodide of Ammonium 180 grains, Carbonate of Ammonium 120 grains, Tincture of Columba 3 fl.ounces, Water sufficient to make a pint. Dose, 1 ]/ 2 teaspoonful before meals, 3 tea- spoonfuls at bed-time. 2164. Fothergill's Asthma Mixture.— Iodide of Ammonium 240 grains, Bromide of Ammonium 360 grains, Syrup of Tolu 6 fl.ounces, Tincture of Lobelia 10 fl.ounces. Mix and dissolve. Dose, a teaspoonful. 2165. Hoffmann's Balsamic Mixture — Mixtura Oleoso-Balsamzca, G. P. — Hoffmann s Balsam of Life. — Oil of Lavender, Oil of Cloves, Oil of Cinnamon, Oil of Thyme, Oil of Lemon, Oil of Mace, Oil of Orange Flow- ers, each 1 part, Balsam of Peru 3 parts, Alcohol 240 parts. Mix them and set the mixture aside for several days in a cool place, shaking occasionally, then filter. 2166. Hope's Camphor Mixture. — Tincture of Opium 80 minims, Nitrous Acid 120 minims, Camphor Water a pint. Dose, a tablespoonful every two hours, for dysentery. 2167. Paris' Carminative Mixture. — Calcined Magnesia y 2 ounce av., Peppermint Water 2^ fl.ounces, Compound Tincture of Lavender ]/ z fl.ounce, Spirit of Caraway 4 fl.ounces, Syrup of Ginger 2 fl.ounces. Mix. Dose, 2 to 4 fl. drachms. 2168. Richard's Chalk Mixture. — Precipitated Chalk 480 grains, Sugar 410 grains, Tincture of Opium 1 fl. drachm, Spirit of Cinnamon 15 minims. Compound Tincture of Lavender 1 fl.ounce, Tincture of Kino 1 fl.ounce, Water 3 fl.ounces. Mix them. Dose, a teaspoonful or more. 2169. Jackson's Cholera Mixture.— Spirit of Lavender Compound 2 fl.ounces, Spirit of Camphor 2 fl.ounces, Tincture of Opium 1 fl.ounce, Spirit of Ether Compound 1 fl.ounce. Mix them. The dose is ]/ z to a teaspoonful. 2170. Jackson's Cough Mixture or Syrup. — Sassafras Pith 60 grains, Gum Arabic 1 ounce av., White Sugar 28 ounces av., Muriate of Morphine 8 grains, Water 1 pint, or sufficient. Put the Sassafras Pith and Gum Arabic in the Water and let stand 12 hours, with frequent stirring, then strain, and dissolve the Sugar in the liquid by stirring. The dose is a teaspoonful. 2171. Sparkman's Cholera Mixture. — Camphor 1 drachm, Kino 2 ounces, Catechu y 2 ounce. Powdered Cinnamon 2 ounces. Powdered Cloves 1 ounce, Powdered Capsicum 2 ounces, Brandy 1 l / 2 pint, Tincture Opium i l / 2 MUCILAGINES — MUCILAGES. 629 fl.ounces, Chloroform i fl.ounce. Macerate for two weeks, and filter. Dose, y z to i teaspoonful. 2172. Sun Cholera Mixture.— Tincture of Opium, Tincture of Capsicum, Tincture of Rhubarb, Spirit of Camphor, Spirit of Peppermint, each 1 fl.ounce. Mix them. The dose is a teaspoonful in water. 2173. Chapman's Copaiba Mixture. — Copaiba 4 fl.ounces, Acacia, pow- dered, 120 grains, Sugar 60 grains, Spirit of Nitrous Ether 4 fl.ounces, Com- pound Tincture of Lavender 2 fl.ounces, Tincture of Opium 1 fl. drachm, distilled Water 4 fl.ounces. Mix. Dose, a tablespoonful. 2174. Alkaline Copaiba Mixture. — Copaiba 4 fl.drachms, Acacia 240 grains, Sugar 240 grains, Solution of Potassa 4 fl.drachms, Spearmint Water sufficient to make 8 fl.ounces. Mix the Copaiba and Solution of Potassa and rub with the Water Acacia, etc. 2175. Copaiba, Santal, and Cubeb Mixture — Nesbit's Specific. — Oil of Santal 5 fl.drachms, Oil of Copaiba 4 fl.drachms, Oil of Cubeb 4 fi. drachms, Oil of Pimenta 1 fl. drachm, Oil of Cassia 1 fl. drachm, Alcohol sufficient to make 16 fl.ounces. Mix and dissolve. Dose, a teaspoonful in water or syrup. 2176. Pancoast's Cough Mixture.— Wild Cherry Bark 240 grains, Sen- ega 240 grains, Ipecac 1 20 grains, Extract of Conium 1 5 grains, Compound Tincture of Cardamom 1 fl.ounce, Compound Spirit of Juniper 1 fl.ounce, Water sufficient to make 10 fl.ounces. Percolate the Bark and Roots with sufficient Water to make 8 fl.ounces. Rub the Extract of Conium with the percolate and add the other ingredients. The dose is 1 to 2 teaspoonfuls. 2177. Gould's Diarrhoea Mixture. — Compound Tincture of Rhubarb 1 fl.ounce, Tincture of Opium 4 fl.drachms, Spirit of Camphor 2 fl.drachms, Water of Ammonia 1 fl.drachm, Oil of Peppermint 30 minims. Mix them. Dose, a teaspoonful in hot sweetened water. 2178. Squibb's Diarrhoea Mixture — Compound Tincture of Opium. — Tincture of Opium 1 fl.ounce, Tincture of Capsicum 1 fl.ounce, Spirit of Camphor 1 fl.ounce, Purified Chloroform 3 fl.drachms, Alcohol sufficient to make 5 fl.ounces. Mix them. The dose is 20 to 60 minims. 2179. Velpeau's Diarrhoea Mixture.— Tincture of Opium 1 fl.ounce, Tincture of Rhubarb 1 fl.ounce, Camphorated Tincture of Opium 1 fl.ounce, Spirit of Peppermint \% fl.ounce, Tincture of Capsicum ^ fl.ounce. Mix them. The dose is 20 to 60 minims. 2180. Laville's Gout Mixture.— Sulphate of Quinine 30 grains, Sulphate Cinchonine 22 grains, Extract of Colocynth 195 grains, Diluted Alcohol 3 fl.ounces, Red Wine sufficient to make 16 fl.ounces. Mix them and dissolve. The dose is a tablespoonful. 2181. Tully's Iron and Conium Mixture. — Subcarbonate of Iron 600 grains, Extract of Conium 300 grains, Sugar 8 ounces, Oil of Cassia 18 630 MUCILAGINES — MUCILAGES. minims, Oil of Gaultheria 20 minims, Compound Tincture of Cinnamon 2 fl. ounces, Tincture of Tolu 4 fl. drachms, Water sufficient to make a pint. Mix them. 2182. Gadberry's Spleen Mixture. — Nitrate of Potassium 300 grains, Sulphate of Quinine 65 grains, Sulphate of Iron 65 grains, Nitric Acid 65 minims, Water sufficient to make a pint. Mix them and dissolve. Dose, a tablespoonful 3 times a day. 2183. Townsend's Mixture — (New-York Hospital). — Red Iodide of Mer- cury 1 grain, Iodide of Potassium 300 grains, Syrup of Orange Peel 2 fl. ounces, Compound Tincture of Cardamom 2 fl. drachms, Water sufficient to make 4 fl.ounces. Dose, 1 to 4 teaspoonsful for Syphilis. MUCILAGINES— MUCILAGES. Mucilages, as they are understood in pharmacy, are thick viscid liquids, prepared by dissolving gums or other vegetable substances, containing mucilage, in water, either cold or by the aid of heat. They are used in medicine chiefly for suspending more active medicinal substances, for soothing irritated internal or external surfaces and for their local action as palliatives. In pharmacy they are used for making pill masses, troches, emulsions, mixtures, etc. The gum mucilages are also extensively used as adhesives for labels, papers, etc., and some of the other mucilages are employed as a base for toilet preparations, such as bandoline, fragrant cream, etc. The Mucilages official in the U.S., Br. and German Pharma- copoeias are as follows : 2184. Mucilago Acacia. Mucilage of Acacia. The U. S. formula is : Acacia in small fragments, 34 parts or 4 ounces av., Water, sufficient to make 100 parts or 9 fl.ounces. Wash the Acacia with cold water, then add to it 66 parts or 7^ fl.ounces of Water, and agitate occasionally until it is dissolved, and strain. MUCILAGINES — MUCILAGES. 631 The Br. P. directs Acacia 4 ounces, and Distilled Water 6 fl. ounces. The G. P. directs 1 part of the Gum to 2 parts of Water. In making Mucilage of Acacia for medicinal use the best quality of Gum Arabic should be selected ; for making " Mucil- age " for adhesive purposes inferior Gum is used. Uses. — In pharmacy Acacia Mucilage is used for making emulsions, many masses, mixtures and compounds. In medi- cine it is employed as a vehicle for suspending powders and other kinds of medicine. 2185. Mucilago Amyli. Br. Mucilage of Starch. Starch, 120 grains or 24 parts. Distilled Water, .... 10 fl. ounces or 875 fl. parts. Triturate the Starch, with the Water gradually added ; then boil for a few minutes, constantly stirring. Uses. — This is a bland Mucilage, which maybe used for the administration of irritating medicines. 2186. Mucilago Cydonii. U. S. Mucilage of Cydonium or Quince. Cydonium (Quince Seed), . . 2 parts or 72 grains. Distilled Water, 100 parts or 16 fl. ounces. Macerate the Cydonium for half an hour in a covered vessel will) the Distilled Water, agitating frequently, then drain the liquid through muslin without pressure. Uses. — In pharmacy this Mucilage is frequently used as a bland vehicle for the administration or application of other medicines, for which it is well fitted, especially for applications to the eye. Made with double the quantity of the Seeds and longer maceration it forms an admirable base for several pop- ular toilet preparations, as fragrant cream, bandoline, etc., which see. 632 MUCILAGINES — MUCILAGES. 2187. Mucilago Salep. G. P. Mucilage of Salep. Salep, in fine powder, I part. Water, 100 parts. Shake the Salep with 10 parts of cold Water, and add 90 parts of boiling Water, mixing them well together. This is similar to Starch Mucilage. 2188. Mucilago Sassafras Medullae. U. S. Mucilage of Sassaf?-as Pith. Sassafras Pith 2 parts or 72 grains. Water, 100 parts or 8 fl. ounces. Macerate for three hours and strain. Uses. — This Mucilage has the flavor of Sassafras, and is used chiefly in cough mixtures. 2189. Mucilago Tragacanthae. Mucilage of Tragacanth. The U. S. formula is : Tragacanth, 6 parts or 190 grains. Glycerin, 18 parts or 1 fl. ounce. Water sufficient to make . 100 parts or 8 fl. ounces. Mix the Glycerin with j6 parts or $y 2 fl. ounces of Water; heat the mixture to boiling, add the Tragacanth and let it macerate for 24 hours, stirring occasionally; then add enough Water to make 100 parts or 8 fl. ounces; beat it to a uniform consistence and strain forcibly through muslin. The Br. formula is Tragacanth, in powder, 60 grains, dis- tilled Water 10 fl. ounces, rectified Spirit 2 fl. drachms. Mix the Tragacanth with the Spirit, then pour in the Water with constant agitation. Uses. — Tragacanth Mucilage is used chiefly as an excipient for pills and to mix with troches and other substances required to be made into a mass. It is also employed as an adhesive for labels, etc. NICCOLUM — NICKEL. 633 2190. Mucilago Ulmi. U. S. Elm, sliced and dried, . . 6 parts or 216 grains. Boiling Water, 100 parts or 8 fl. ounces. Macerate for two hours in a covered vessel and strain. Uses. — Elm Mucilage is a favorite domestic remedy for coughs and irritation of the throat, taken as a drink ad libitum. Other Mucilages. Mucilages are sometimes made from other mucilaginous sub- stances, the principal ones being as follows: 2191. Mucilage of Fenugreek. — Digest 1 part of Fenugreek Seed in 10 parts of Water for 12 hours, then boil and strain. 2192. Mucilage of Linseed. — Digest 1 part of Linseed (Flaxseed) in 6 parts of warm Water for 6 hours, stirring occasionally, and strain. 2193. Mucilage of Liquorice. — Pour 6 parts of boiling Water on 1 part of Liquorice Root, cut in fine pieces, and, after a few hours, strain. 2194. Mucilage of Marsh Mallow. — Make in the same proportion and manner as the preceding. NICCOLUM — NICKEL. Symbol, Ni ; Atomic weight, 38 ; Sp. gr., 8.9. Nickel is a metal classed chemically with cobalt and tin, obtained from ores found in different parts of the world by fusing them and separating the Nickel by various means. It is hard, white, malleable and magnetic, resembling silver, but harder, being therefore better adapted for plating, for which it is extensively used. It forms alloys with copper and zinc, known as German Silver, Albata, etc. (482), which are much employed as a basis for silver-plated ware. It is also used as a coin of small denomination, in the United States. Its salts are not used in medicine, but some of them are extensively used in silver-plating solutions. 634 NICCOLUM — NICKEL. The following are the principal salts of Nickel: 2195. Acetate of Nickel — Ni(C 2 H 3 2 ) 2 .— By adding Carbonate of Nickel to Acetic Acid until neutralized, concentrating and crystallizing. 2196. Bromide of Nickel— NiBr- —By neutralizing Hydrobromic Acid with Carbonate of Nickel, concentrating and crystallizing. 2197. Carbonate of Nickel — NiC0 3 . — This may be made by adding Carbonate of Sodium to a solution of Chloride of Nickel and collecting the precipitate, or by heating Chloride of Nickel with Carbonate of Sodium in sealed tubes. 2198. Chloride of Nickel— NiCl„. — By neutralizing Hydrochloric Acid with Carbonate of Nickel, concentrating and crystallizing, or by heating Nickel filings to low redness in a current of Chlorine. Double Chlorides of Nickel with Ammonium, Potassium or Sodium, may be made by combining solution of Chloride of Nickel with Solution of Chlorides of the substances named. 2199. Cyanide of Nickel — NiCN 3 . — By adding a solution of Cyanide of Potassium to a solution of any Nickel Salt in slight excess and collecting the precipitate. 2200. Hydrate of Nickel — Ni (HO) 2 .— By precipitating a solution of any soluble Salt of Nickel with Caustic Potassa. This may be dissolved in Acids for making any of the Soluble Nickel Salts. 2101. Oxides of Nickel. — With Oxygen Nickel forms two oxides, the Monoxide, NiO, being of an olive-green color, and the Sesquioxide, Ni 2 3 , a black powder. 2202. Sulphate of Nickel — NiS0 4 . — By dissolving Carbonate or Oxide of Nickel in Sulphuric Acid diluted with water, concentrating and crystal- lizing. This salt is obtained in pale-green crystals, and is much used for nickel-plating. Double Sulphates of Nickel with Ammonium, Potassium and Sodium, may be made by mixing a solution of Sulphate of Nickel with a solution of the Sulphates of the other substances. The Double Salts of Nickel, as they are called, are much used for nickel-plating. NITROGENIUM— NITROGEN. Symbol, N. ; Atomic weight, 14; Sp.gr. 0.97. Nitrogen is a colorless, odorless and tasteless gaseous element, discovered in 1722 by Rutherford, and found to be a constitu- ent of the atmosphere (of which it forms about four-fifths), by NITROGENIUM — NITROGEN. 635 Lavoisier, in 1755. It is also called Azote. It is an essential part of nearly all animal matter, and enters largely into the composition of vegetable substances, and in the form of salts forms an important portion of alluvial soils. In the atmos- phere it serves the purpose of diluting the oxygen. In a free gaseous state its qualities are neutral and negative, but com- bined with other elements it forms very energetic compounds. With hydrogen only one combination is known — Ammonia, NH 3 — from which are derived a great number of valuable substances ; with carbon it forms Cyanogen, CN, the basis of a class of poisonous salts. Its combinations with oxygen are of the greatest importance, forming acids which unite with bases to produce Nitrites and Nitrates. It is also an essential constituent of all alkaloids, and many other principles of plants. Nitrogen is most readily obtained by boiling a solution of Nitrate of Ammonia and collecting the vapor, which consists of water and nitrogen gas. Oxides of Nitrogen. With Oxygen, Nitrogen forms 5 distinct compounds, which are as follows : 2203. Nitrous Oxide or Laughing Gas — Monoxide of Nitrogen — N 2 0. — This is made by heating fused Nitrate of Ammonium, free from Chloride, in a glass retort, to about 200 C. (392 F.), and gradually increasing the heat as the decomposition proceeds. The salt is decomposed into water and nitrous oxide, the gas is washed by passing through warm water. This is the popular exhilarant known as Laughing Gas, or Hyponitrons Oxide, which is inhaled before drawing teeth or other minor surgical operations. 2204. Nitric Oxide — Dentoxide or Binoxide of Nitrogen — NO.— This is most readily obtained by pouring Nitric Acid on copper shavings in a retort, effervescence ensues, and the arising gas, Nitric Oxide, is collected. 2205. Nitrous Anhydride — Trioxide of Nitrogen — N 2 3 . — By heat- ing Starch in powder, 1 part with Nitric Acid, sp. gr. 1.25, 8 parts, in a retort, and ( ollecting the evolved gas, which must be passed through a long drying- tube containing Chloride of Calcium, etc., and then condensed by cold to a blue liquid. 2206. Nitrogen Pentoxide or Nitric Anhydride — N 2 5 . — The process for making this substance is difficult and tedious. It is obtained in colorless crystals, which melt at 86°F., and boil at 1 i$°F. 2207. Nitrogen Peroxide or Nitric Peroxide — N„0 4 . — This may be obtained by heating dried Nitrate of Lead in a retort and condensing the gas 636 OLEA — OILS. which is evolved, by cold. In the absence of any moisture it crystallizes in clear transparent crystals, but if any moisture be present it forms a liquid. Nitrogen also combines with Chlorine and Iodine, forming explosive com- pounds, with Glycerin forming Nitro-Glycerin, with Benzol forming Nilro- Benzol, etc. Acids of Nitrogen. By absorbing or uniting with the elements of water, the two Anhydrides of Nitrogen form Acids as follows : 2208. Nitrous Acid — HN0 2 . — This is a solution of Nitrous Anhydride, N 2 3 . in water. The commercial Nitrous Acid, which is usually dispensed for this is a reddish acid containing Nitric Acid with Nitrogen Tetroxide, N 2 4 . The fumes which arise when Nitric Acid is boiled are principally Nitrous Acid. Nitrous Acid combines with bases forming Nitrites, and is sometimes employed in medicine for external use chiefly. 2209. Nitric Acid — HNO3. — This Acid is formed by the addition of the elements of water to Nitric Anhydride or Nitric Oxide, N 2 5 +H 2 0=(HN0 3 ) 2 . The U. S. P. describes it as a liquid compound of 69.4 per cent, of Absolute Nitric Acid and 30.6 per cent, of Water. This description corresponds to the C. P. or 43 Nitric Acid. Commercial Nitric Acid is known as 38 Acid, and contains more or less acids of lower oxidation. It is also known as aqua fortis, and is used to combine with bases forming Nitrates, and in medicine largely diluted as a tonic and astringent. (See page 62.) Nitric Acid is the commercial bases of the Nitrates, and is made by dis- tilling Nitrate of Sodium or Potassium with concentrated Sulphuric Acid. Fuming Nitric Acid, or Nitroso-Nitric Acid, is Nitric Acid containing a considerable amount of Hyponitric Acid. Commercial Nitrous Acid is a weak preparation of this composition. Aqua Regia is a mixture of 3 parts of Nitric Acid with 4 parts of Hydro- chloric Acid. It is a solvent for gold. OLEA — OILS. Under this heading is classed a great variety of substances ranging from liquids to solids, and obtained from the mineral, animal, and vegetable kingdoms. They are very properly divided pharmaceutically into Fixed Oils, which are obtained by expression from fatty bodies, and Volatile Oils, which are mainly obtained by distillation, and these again may be arranged in several groups according to their characteristics, OLEA — OILS. 637 manner of making, etc. To these classes may be added the Mineral Oils, which, though not officially recognized, are con- siderably used in pharmacy, and many Mixed and Medicated Oils, which have their uses in the art. Fixed Oils. Fixed Oils are fatty bodies either liquid or solid, obtained, usually by expression, from vegetable or animal substances of a fatty nature. They differ from Volatile Oils by having a greasy feeling to the touch, while Volatile Oils do not, and by leaving a permanent oily spot on paper, while Volatile Oils do not. Volatile Oils are also vaporized by a degree of heat which will boil water, while the Fixed Oils remain unchanged. In the arts, the Fixed Oils, both of vegetable and animal origin, are extensively used for many industrial purposes, but in pharmacy no animal oils, except lard oil and cod liver oil, are officially recognized. The Fixed Oils and fats are, chemically, oxides of glyceryl or compound ethers, produced by the union of the fatty acids peculiar to each substance with glycerin (glyceric alcohol). They consist generally of the neutral principles, Oleiu, C 3 H 5 (C 18 H 33 2 )3, which is liquid, combined with Pahnatin or Stcarin, which, when separate, are solids at ordinary tempera- tures, but when combined with Olein are soluble in it at ordinary temperatures, but are congealed at lower temperatures, making many of the Fixed Oils solid in winter and fluid in summer. Margarin is considered a mixture of Stearin with other like principles. These neutral principles may be decomposed into Glycerin and Oleic Acid, C 18 H 34 2 , Stearic Acid, C 18 H 30 O 2 , and Palmetic Acid, < ! 16 H 82 8 . Fixed Oils are obtained by pressing the fatty substances, either with or without the aid of heat, in strong layer presses, by which the oily liquids are separated from the more solid fatty matters, or from the solid constituents of seeds, etc. Some of the Fixed Oils (especially flaxseed oil) arc also obtained by solution in naphtha, which is afterwards evapo- rated, leaving the Fixed Oil. 638 OLEA — OILS. The following are the Fixed Oils official in the U. S., Br., and German Pharmacopoeias : 2210. Oleum Adipis— Lard Oil. — A Fixed Oil obtained by expression from lard at a low temperature. This is known on the market as summer- strained and winter-strained Lard Oil, the winter-strained being pressed at a much lower temperature and therefore remaining fluid at lower temperatures than the former. Lard Oil is used as a lubricant and in pharmacy for making citrine ointment, hair oil, etc. 221 1. Oleum Amygdalae Expressum — Expressed Almond Oil. — A Fixed Oil expressed from sweet or bitter Almond. The Almonds are deprived of the colored powder adhering to them, by rubbing together, or are blanched, then ground in a mill and the meal enclosed in strong linen bags and pressed between warmed iron plates. The yield is 35 to 40 per cent. The sp. gr. 0.915 to 0.920. Used for making rose-water ointment and whenever a fine bland Oil is required. 2212. Oleum Cocos. G. P. — Coco-Nut Oil. — A Fixed Oil expressed from the seed-kernels of Coca Nucifera, having a white color and the con- sistence of butter. This is considerably used as a lubricant and emollient. It has the odor of coconut. 2213. Oleum Gossypii Seminis — Cotton Seed Oil, U. S. — A Fixed Oil expressed from the seed of Gossypium herbaceum and subsequently purified. The kernels of Cotton Seed are separated from their testa, ground, and the oil expressed by powerful pressure. It is then purified by treating and filter- ing, and put upon the market under various names, and for various purposes. The ordinary Cotton Seed Oil is largely used to adulterate Linseed Oil and Olive Oil, and is sold as cheap Paint Oil and Sweet Oil. The finer grades are known as Salad Oil, Union Salad Oil, etc. Although directed for making several liniments, etc., in the U. S. P., it has not proven very satisfactory. It is considerably used as a base for hair oil. 2214. Oleum Lauri — Expressed Oil of Laurel, G. P. — An oil expressed from the fruit of Laurus Nobilis, of the consistence of lard, and consisting both of fixed and volatile oils. It is dark-green and aromatic. 2215. Oleum Lini — Flaxseed Oil, Linseed Oil. — A Fixed Oil expressed from flaxseed without the use of heat. This Oil is now mostly made by treating or percolating the ground flaxseed with naphtha, and then distilling off the naphtha, the Linseed Oil being left in the boiler of the still and subse- quently purified. Linseed Oil is extensively used for painting and other industrial purposes, and in pharmacy for making liniments, etc., and inter- nally as a laxative. 2216. Oleum Morrhuse — Cod Liver Oil. — A Fixed Oil obtained from the fresh livers of Gadus Morrkua, or other species of Gadus. This Oil is prepared in the cod-fishing districts by heating the fresh livers in a wooden OLEA — OILS. tank by means of steam. The oils and other matters are drained off and separated by standing, and the Oil filtered, then cooled or frozen that it may deposit the heavier fats, then pressed in linen bags to obtain the pure light oil. Cod Liver Oil is extensively used in medicine, plain and combined in many ways. The dose is a teaspoonful to a tablespoonful. This is often prescribed by the name Oleum Jacoris Aselli, its German-Latin title. 2217. Oleum Myristicae Expressum — Expressed Oil of Nutmeg. Br. — A concrete Oil obtained by means of expression and heat from Nutmeg. This is of the consistence of lard and is called Myristica Adeps, also Butter of Nutmeg. The German-Latin title is Oleum Nucistce. It is used as a vehicle for other medicines. 2218. Oleum Olive — Olive Oil.- — A Fixed Oil expressed from the ripe fruit of Olea Europoea. This Oil has been extensively used in pharmacy in all countries, and is an important article of commerce. The finer grades, which are obtained from the first expression of choice fruit, are called Virgin Oil ; the cheaper grades are made after the Virgin Oil has been expressed by heating the cake with boiling water and strong expression. Imported Salad Oil is a fine quality of Olive Oil. In pharmacy it is used in liniments, plas- ters, and ointments, and for many other purposes. The color of Olive Oil is from a light straw to a greenish yellow. It sp. gr. is about 0.917. 2219. Oleum Papaveris — Poppy Oil. G. P. — A Fixed Oil expressed from the seeds of Papaver somniferum. This is a very bland Oil, free from irritating qualities and albuminous matter. It is sometimes employed in medicine and is used for fine painting and to oil watches, etc. It is fre- quently sold as Watchmakers' Oil. 2220. Oleum Rapae— Oil of Rape Seed. G. P.— A Fixed Oil obtained by expression from the seeds of the cultivated varieties of Brassica or Rape. This is a bland Oil, used for the same purposes as Oil of Cotton Seed or Mustard. 2221. Oleum Ricini — Castor Oil. — A Fixed Oil expressed from the seed of Ricinus Communis. The seeds or beans of the Castor Oil plant are crushed and subjected to powerful pressure, and then purified by heating with water to remove albuminous matter. The clear Oil is then filtered and constitutes the cold-pressed Castor Oil of Commerce. An inferior quality is made by pressing the cake between heated plates. Castor Oil is a well- known cathartic in doses of a teaspoonful to a II. ounce. It is much more effective in the form of an emulsion. It mixes with alcohol in all proportions and is considerably used as a base for hair oil, mixed 2 parts of Oil with 1 part of alcohol. 2222. Oleum Sesami — Oil of Sesamum — Oil of Bcnntf. U. S. — A Fixed Oil expressed from the seeds of Sesamum Indicum. This is a bland, odorless Oil, similar to Oil of Almond or Olive Oil, and may be used for sim- ilar purposes. It is highly esteemed as a base for hair oil. 640 OLEA — OILS. 2223. Oleum Sinipis Expressum — Expressed Oil of Mustard. — A Fixed Oil obtained by expression from the seeds of Sinapis alba or nigra. This Oil very much resembles Cotton Seed Oil. It is made chiefly in Califor- nia, and is used as a base for hair oil and other similar purposes. 2224. Oleum Theobromae — Oil of Theobroma, Butter of Cacao. — A Fixed Oil expressed from the seeds of Theobroma Cacao. This Oil resem- bles tallow, and is made by pressing the kernels or nibs of the chocolate nut between hot iron plates and running the Oil into moulds. It is used in phar- macy for making suppositories, for which it is best adapted of any substance having a low melting point (86° to 95 F.), and a firm consistence when cold. It is sometimes used in ointments, and is a favorite requisite for the toilet for rubbing over the face, hands, lips, etc. 2225. Oleum Tiglii, U. S. Oleum Crotonis, Br. P. and G. P.— A Fixed Oil expressed from the seed of Croton Tiglium. This Oil is employed externally as a rubefacient and vesicant. Internally it is a powerful purgative in doses of 1 drop. It is sometimes combined in pills, but seldom given in any other form on account of its irritating effect. The following are official formulae for preparations contain- ing a Fixed Oil as a solvent of medicinal agents. For Oleum Sulphuratum, see page 186. 2226. Oleum Cantharidatum — Cantharides Oil. G. P. — Cantharides 3 parts, Oil of Rape Seed 10 parts. Digest for 10 hours on a steam-bath, express and filter. This is applied as a vesicant and rubefacient. 2227. Oleum Hyoscyami —Hyoscyamus Liniment. G. P. — Hyoscyamus, cut, 4 parts, Alcohol 3 parts. Macerate for a few hours, then add Olive Oil 40 parts, and digest on a steam-bath, stirring occasionally, until the Alcohol is evaporated. Finally, express and strain. This is used as a sedative sooth- ing application. Other medicated Oils prepared in a similar manner are classed as Olea Cocta. Either green or dried plants are used, and they may be prepared either with or without alcohol to aid in extracting the prop- erties of the drugs. Oil of Belladonna, Capsicum, Colocynth, Elder leaves, also called Green Oil or Oil of Swallows, Digitalis, Conium, etc., are made as above. 2227. Oleum Phosphoratum — Phosphorated Oil. — The U. S. formula is : Phosphorus 1 part, Stronger Ether 9 parts, expressed Oil of Almond sufficient to make 100 parts. Introduce a sufficient quantity of the Almond Oil into a flask, heat it on a sand-bath to 250 C. (482 F.) and keep it at that tempera- ture for 1 5 minutes, then allow to cool and filter it. Put 90 parts of the fil- tered Oil together with the Phosphorus, previously well dried by blotting paper, into a dry bottle capable of holding somewhat more than 100 parts, insert the stopper and heat the bottle in a water-bath until the Phosphorus melts, agitate it until the Phosphorus is dissolved and allow it to cool, then add the Ether. OLEA — OILS. 641 The Br. formula directs 16 grains of Phosphorus to be dissolved in 4 fl. ounces of Oil of Almonds, in a similar manner, but Ether is not used. Phosphorated Oil contains 1 per cent, of Phosphorus, and is given in doses of 3 to 5 minims, usually in the form of an emulsion. Other Fixed Oils. Besides the official Fixed Oils which have been mentioned, quite a number which have no official recognition are used in pharmacy. The following are the most important: Animal Oils. 2228. Oleum Animale ^Ethereum — Dippel's Animal Oil. — This was formerly official in the P. G. It is obtained by dry distillation from bones and animal substances, and is known as bone oil. It has a very fetid odor, which is removed by rectifying, the purified oil being used in smelling salts, etc. 2229. Bear's Oil or Bears Grease. — This is obtained by "trying out" the internal fat of the bear. It resembles lard, and is much esteemed as a base for hair pomade, a popular article of this kind being known as " Ursina." Goose Oil, Hen's Oil, Rattlesnake Oil, Skunk Oil, and Woodchuck Oil, are all made in a similar manner, and are used in domestic medicine externally for swellings, rheumatism, etc., and sometimes internally for croup, etc. Angleworm Oil. — This may be made by putting a quantity of Angleworms in a bottle, covering them with Olive Oil and keeping them exposed to sun- shine for several days until a sediment has separated. The Oil is then decanted and filtered or strained. This may also be made by "trying out" the Oil by heat. It is a domestic remedy for rheumatism, stiff joints, etc. Lanolin is a fatty Oil obtained from the washings of wool, and now con- siderably used as an ointment base. It is more readily absorbed than other fats. It is also known by other names, as Oleum Lanae, Agnine, etc. 2230. Neatsfoot Oil.— This is made by boiling the feet of cattle, deprived of their hoofs, in water and removing the Oil which rises to the surface, and after it has stood sometime in warm water straining it. This is used for softening leather, for stiff joints, etc., and in some liniments. 2231. Sperm Oil.— This is obtained from cavities in the head of the Sperm and is the source of Spermaceti. Sperm Oil when purified is exten- sively used as a lubricating oil for tine machinery. It constitutes the best Machine Oil. It is best purified by heating to coagulate any albu- minous matter, then filtering, and then chilling with ire and pressing out in linen bags. 2232. Whale Oil.— An Oil obtained by "trying out" the " blubber " of the Whale. It is chiefly used f< r. Many other Fish Oils 642 OLEA — OILS. are used for similar purposes, as Menhaden Oil, Porpoise Oil, Seal Oil, Shark Oil, Walrus Oil, etc. Dugong Oil and Eulachon Oil have been proposed as substitutes for Cod Liver Oil, but are not used in this country. Vegetable Oils. 2233. Nut Oils. — These are prepared, as a rule, by grinding- the kernel or ' meat " of the nuts to a coarse meal and expressing- the Oil, either by cold expression or between heated iron plates. The Oils from nuts are generally bland and have an odor somewhat resembling the nuts from which they are obtained. Beech-Nut Oil, Brazil-Nut Oil. Ground-Nut Oil, Hazle-Nut Oil, Hickory- Nut Oil, Walnut Oil, Peach-Pit Oil, and other similar Oils are obtained in this manner. Coco-Nut Oil, Candle-Nut Oil, Bayberry Oil, and other solid Oils are obtained by boiling the nuts or fruit in water, expressing while hot, and collecting the oil when cold from the surface. 2234. Oils from Seeds.— The Oils from seeds are prepared either by expression or by percolating the ground seeds with Naphtha, Ether, or some other solvent of the Oils and then evaporating the light substance by distilla- tion, leaving the Oil in the boiler of the still, the latter process being usually preferred as it insures a larger yield of the Oil at a less expense. The fol- lowing unofficial Oils are made in this manner : Oil of Cardamom, Oil of Melon Seed, Chaulmoogra, " Niker Seed, Cucumber Seed, " Pumpkin Seed, Ergot, " Stramonium Seed, Hemp, " Sunflower Seed, Hyoscyamus Seed, " Tonka. Larkspur Seed, 2235. Oils from Fruit. — The Oils from fruit are usually obtained by making the fruit into a pulp and steeping in water, then pressing and collect- ing the Oil which rises to the surface, Palm Oil is the most used of any unofficial Oil of this kind, large quantities being consumed in the manufac- ture of soap. Mangosteen Oil, Behn Oil and Tucum Oil are sometimes used. Volatile Oils. Volatile Oils are obtained from plants mainly by the process of distillation. They consist generally of the odorous princi- ples of the plants from which they are obtained, and are there- fore called Essential Oils. The term Otto instead of Oil is used in perfumery to designate the Essential Oils, as being less liable to mislead when there are Fixed and Essential Oils from the same substance. OLEA — OILS. 643 The Volatile Oils are divided chemically into several classes : Hydrocarbons or Terpenes, which consist of carbon and hydrogen (usually C 10 H 16 ), of which Oil of Turpentine is the type. Oxygenated Oils, which contain oxygen combined with the hydrocarbon radical, and of which Cinnamon Oil is an example. Sulphurated Oils, which contain Sulphur combined with a hydrocarbon radical, of which Volatile Oil of Mustard is an example. Nitrogenized Oils, which contain Hydrocyanic Acid, or Ni- trogen combined with a Hydrocarbon radical, of which Essen- tial Oil of Almond and its associates are all that are known. Many of the Volatile Oils which have chemically the same composition are entirely different in odor and other character- istics. For example, Oil of Turpentine, Oil of Orange, Oil of Lemon, and Oil of Bergamot, are all terpenes, having the chemical formula C 10 H 1G , their difference consisting only in the arrangement of the Carbon and Hydrogen atoms in the molecule. Volatile Oils consist generally of two parts, which volatilize or congeal at different temperatures, as would a mixture of alcohol and water. The lighter or more etherial portion may be separated by distillation at a moderate temperature, and is much more soluble than the heavier portion which remains behind. By congealing or freezing many of the Oils a solid matter is obtained, which is called Stearopten. This may be collected and separated from the Oil by pressure. The terpenes are designated by the termination entoxides, as they combine with I, 2, 3, 4 or 5 volumes of Oxygen. Oxides which are reduced from hydrates by depriving them of the elements of water, without otherwise changing their composition, are frequently called anhydrides. In combination with hydrogen Oxygen unites with many positive bases, form- ing hydrates or hydroxides. Oxygen is most readily obtained for experimental purposes by heating Chlorate of Potassium with about one-eighth its weight of manganese dioxide in a flask and collecting the gas. The combinations of Oxygen with bases are noted under the basic substances with which it combines. Oxidation is the operation by which Oxygen combines with other substances forming Oxides. The term oxigenation is sometimes used to describe the same process. Ozone is an allotropic form of Oxygen, produced by the union of three atoms of Oxygen in one molecule, while the Oxygen molecule is composed of but two atoms. It is a color- less gas, having a peculiar unpleasant odor, and rapidly chang- ing into normal Oxygen. It is a wonderful bleaching and de- odorizing agent. It is produced by the action of electricity on Oxygen and by other methods, and was formerly called electri- fied air. 2435. PANCREATINUM — PANCREATIN. Pancreatin is a ferment, the agent by which fats are con- verted into emulsions before entering the circulation. It is obtained for medicinal use from the Pancreas of beef by chop- ping them fine, macerating with successive portions of water, PANCREATIN. PEPSIN. acidulated with Hydrochloric Acid (i part to 30), straining the liquids, then filtering through coarse paper, neutralizing by adding Carbonate of Calcium, again filtering, adding to the filtrate an equal bulk of Alcohol, and after standing gathering the precipitate, washing, pressing between bibulous paper and drying. The product is a transparent, brittle, yellow mass, which might properly be called Crystal Pancreatin. This is used in pharmacy in making emulsions and elixirs, and in medicine to aid the assimilation of fats. The dose is 5 to 10 grains. 2436. Pancreatinum Saccharatum. Saccharated Pancreatin. Pancreatin, 1 part or 1 ounce. Sugar of Milk, 9 parts or 9 ounces. Powder them together. The dose is from 20 to 60 grains or more. 2437. PEPSINUM - PEPSIN. Pepsin is a ferment, the agent by which a portion of the food which is taken into the stomach is dissolved and fitted for assimilation. It is obtained from the lining or mucous mem- brane of the stomachs of various animals, that from the stomach of the hog being preferred for most purposes. Prof. Scheffer's method is now quite generally employed. It is as follows : The fresh stomachs are deprived of their fat and divested of their outer coating, cut open, gently washed with cold water, and macerated for several days in a " pickle " com- posed of Water 30 parts, and Hydrochloric Acid 1 part, with frequent stirring. The liquid is then strained and filtered clear through coarse paper, or allowed to stand 24 hours, and then poured off. Common salt is then added and thoroughly mixed with the liquid. The Pepsin rises to the top, and after PEPSINUM — PEPSIN. 669 standing is skimmed off and drained in a strainer, then sub- mitted to strong pressure to force out all that is possible of the saline solution, and carefully dried in warm air without heat. This constitutes the Crude Pepsin which is used for making Purified Pepsin, Saccharated Pepsin, etc. Purified Pepsin or Scale Pepsin. — This is prepared by redissolving the crude Pepsin, before drying, in water acidu- lated with Hydrochloric Acid, then adding just sufficient salt to separate it from its solution, washing it gently with cold water and draining, pressing, and drying rapidly on glass with gentle heat. Crystal Pepsin. — A Pepsin bearing this brand is prepared by Dr. Carl L. Jensen, of Philadelphia. The process by which it is prepared is said to be by subjecting the stomachs to the action of heat and dilute acid, whereby a gastric digestion takes place and a Peptone containing their digestive ferments is produced. It is then purified and dried in the manner above described. Many rival manufacturers of Pepsin under different names urge the superiority of their product, but the process as given (2437) is believed, if properly conducted, to produce the most reliable of any. 2438. Pepsinum Saccharatum. Saccharated Pepsin. Saccharated Pepsin is now official in the U. S. and may be prepared as follows : Scale or Crude Pepsin, . . . . I part or 1 ounce. Sugar of Milk, 9 parts or 9 ounces. The value of this preparation must, of course, depend upon the scale or crude Pepsin which is employed. The pharmaco- pceia requires that 1 part of the finished product dissolved in 500 parts of water acidulated with 7.5 parts of Hydrochloric Acid shall digest at least 50 parts of hard-boiled egg albumen, in 5 or 6 hours, at a temperature of 38 to 40 C. (iOO° to 104 F.) It is a fact that much of the Saccharated Pepsin of the market is nearly worthless. 670 PEPSINUM — PEPSIN. PEPTONES. 2439. Pepsin Compound. Compound Powder of Pepsin. Scale or purified Pepsin, 10 parts. Pancreatin, pure, 10 parts. Diastase (Vegetable Ptyalin), 1 part. Lactic Acid, I part. Hydrochloric Acid, 3 parts. Sugar of Milk, 75 parts. Powder the Pepsin and Pancreatin by rubbing with the Sugar of Milk, add the Diastase, and, when they are all reduced to a fine powder and intimately mixed, add the Acids first to a small portion by rubbing them well together and then add the remainder and mix. If Saccharated Pancreatin and Pepsin are used, 47^ parts of each should be used and the Sugar of Milk omitted. Under the name " Lactopeptine" a preparation put up by the New-York PJiarmacal Association has had an extensive sale. Its composition is similar to the foregoing. 2440. PEPTONES. Peptones are formed by the action of Pepsin or Pepsin, Pancreatin, etc., on albuminous foods or substances. They are in fact partially digested foods, fitted for assimilation. Several manufacturers have introduced preparations containing Peptones, to aid disordered peptic digestion, etc. They are usually made by chopping lean beef very fine and macerating it for about 6 hours in a Solution of Pepsin with water and hydrochloric acid, at a temperature of about 104 F. The beef is thus mostly dissolved, the mixture is strained, and the solution may be combined with various medicines as may be required. Excess of Pepsin and Pancreatin are sometimes added, and the solution thus prepared is added to wine, elixirs, emulsions, etc. The liquid Peptone is also evaporated and furnished in the form of a scale salt, as Beef Peptone. PETROLEUM. 671 PETROLEUM. This important hydrocarbon, which is obtained from the earth by drilling " oil wells," is the source of many valuable sub- stances employed in pharmacy and medicine. As obtained from the earth it is called " Crude Oil," or " Crude Petroleum." By fractional distillation several light etherial products are first obtained, then the illuminating oils, and after these the heavier products, among which are Petrolatum and Paraffin. Crude Petroleum is considerably used in liniments for rheu- matism, swellings, etc. The lighter products of the fractional distillation of Petro- leum are 2441. Cymogene, Sp. gr. 0.590, which boils at 32 F., the freezing point of water, and is only obtained by condensing the vapors, which first pass over, by a specially constructed pump. It has no practical use. 2442. Rhigolene, Sp. gr. 0.625. Boils at 65° F., and is condensed by ice and salt from the first vapors that come over. It is used for freezing mixtures, and as a spray for local freezing in surgical operations. It must be handled with great caution. 2443. Gasoline, Petroleum Ether or Benzine.— Sp. gr. 0.665 to 0.675. Condensed in a worm by cold water. It is extensively used for vaporizing in gas machines and for burning in properly-constructed stoves, also for re- moving grease and as a solvent for fixed oils. This is the Official Benzine, see page 189. 2444. Naphtha. — Sp. gr. 0.695 to 0705. This is a heavier form of Gaso- line, used for burning and as a solvent for oils, etc. See page 1 89. 2445. Benzine.— Sp. gr. 0.725 to 0.737. This was formerly extensively used as a substitute for Turpentine, but is now little employed except as a solvent for gums, in making some kinds of varnishes and rubber. It is mostly worked in with the illuminating oils. 2446. Carbon Oil or Refined Petroleum.— Sp. gr. 0.800 to 0.815. This is the Illuminating Oil which varies considerably in sp. gr. etc., as made for different purposes and by different houses. The standard test at which Carbon Oil will flash or explode when heated, is regulated by legislation in different States from 120 F. to 150 F., New- York test being 138 F. Signal Oil, which is burned in lanterns and locomotive engines, is a still higher test oil usually mixed with Sperm Oil. After the illuminating Oils are obtained, lubricating Oils are separated, then the heavier products Petrolatum, Paraffin (370), Carbolic Acid, and other derivatives, which correspond to the products obtained from Coal Tar. 672 PETROLATUM. PHENYL. 2447. PETROLATUM. Cosmoline, Vaseline, Petroleum Ointment, etc. This is official in the U. S. P., and is described as a semi- solid substance consisting of hydrocarbons chiefly of the marsh-gas series (C 16 H 34 , etc.), obtained by distilling off the lighter and more volatile portions from American Petroleum and purifying the residue. Its melting point is from 104 to 125° F. This substance is mostly prepared from the residuum which collects in storage tanks, oil wells, etc., which is famil- iarly known as " B. S. Oil." From this the lighter portions are distilled and the residue transferred to large percolators or cylinders, partly filled with freshly-prepared animal charcoal (bone black) and kept heated by proper appliances to a degree which will liquefy the oil. As it comes through the percolator it is deodorized and decolorized, the first portions being white when cold and the later runs being from a light amber to a dark color. It is then brought up to the proper melting point, which is usually 104 F., by adding paraffin and mixing them thoroughly. Uses. — The value of this product as an ointment base has caused it to be almost universally adopted for that purpose in advance of official directions. It does not become rancid by age. It is claimed that it is not so readily absorbed as lard, and that some desired chemical changes in some ointments do not take place when this is used. These objections are noted under the proper formulas. Paraffin, Paraffin Oil, Lubricating Oil, and other Petroleum products have been noticed elsewhere. PHENYL. Phenyl is the hypothetical radical of the Phenyl series of compounds, of which Phenol and Phenylamine are derivations. 2448. Phenol or Carbolic Acid— C 6 H 5 HO.— A product of the distilla- tion of coal-tar between the temperatures of 180 and 190 C. (356 and 374° F.). PHENYL. PHOSPHORUS. 673 Carbolic Acid or Phenol is the hydrate of Phenyl, or Phenic Alcohol. Crude Carbolic Acid is a liquid distilled from coal-tar, containing many empyreumatic products. Pure Crystallized Carbolic Acid is made by distill- ing crude Carbolic Acid and purifying the crystallized product obtained by repeated distillations. (See 28.) Cresylic Acid or Cresol, C 7 H 8 0, is a homologue of Carbolic Acid, very similar to it, but less soluble. Phenol-pthalein is prepared from Phenol and Pthalic Anhydride. It is used in making a test solution. 2449. Phenylamine or Aniline, C 6 H H 3 N, is the base of the Aniline salts so extensively used for dyeing. (See 179.) It is prepared by treating an alcoholic solution of Nitrobenzol with Ammonia and Hydrogen Sulphide until Sulphur is precipitated. The liquid portion is again treated with Hydro- gen Sulphide until no more sulphur can be precipitated. The liquid is then mixed with an excess of acid, filtered, boiled, and distilled with an excess of Caustic Potassa. PHOSPHORUS. Symbol, P; Atomic weight, 31. Phosphorus is a non-metallic element, existing in nature mainly in the form of salts, and obtained for use by decom r posing its compounds. It is mostly prepared from Acid Cal- cium Phosphate by heating with charcoal and collecting the distillate under warm water, afterward filtering by squeezing through chamois leather under warm water, theii moulding it in sticks, in which form it comes into the market. Phosphorus assumes several allotropic forms under different treatment. In its normal condition, as above described, it is the ordinary Phosphorus of the market, pale-yellow, semi- transparent; soft and waxy when warmed to about 75°F., melting at iii°F., taking fire in the air at l65°F., and slowly oxidizing in the air at all temperatures above 6o°F. It must be preserved under water. Uses. — Phosphorus is extensively used in making matches, ami in the form of pills and solutions is considerably employed in medicine as a nerve tonic and vitalizer. Its acids and salts are important pharmaceuticals extensively used both in medi- cine and pharmacy and in the industrial arts. The dose of Phosphorus is from , ,', „ to ,,'„ grains, in pills or solution. 674 PHOSPHORUS. Allotropic Forms of Phosphorus. Phosphorus assumes under different treatment several allotropic forms, which, although different in physical characteristics, are the same chemically. 2450. Red or Amorphous Phosphorus is prepared by exposing ordinary phosphorous to an atmosphere of Carbonic Acid at 225° to 25o°C. for several days, when it is converted into a red, amorphous mass, having entirely differ- ent properties than ordinary phosphorous, being non-luminous, non-combus- tible at ordinary temperatures, and non-poisonous. . When heated to 28o°C. it is reconverted into ordinary phosphorus. White Phosphorus, Black Phosphorus, and Liquid Phosphorus are other allotropic forms obtained by various treatment but are not used in pharmacy. Combinations of Phosphorus. Phosphorus combines with the metallic bases forming Phosphides, the more important ones being noticed under the metals with which it combines. It also unites with the non-metals, forming compounds, the more important of which are here noticed. 2451. Chloride of Phosphorus — PC1 5 . — By the spontaneous combustion of Phosphorus in an excess of dry Chlorine, or by passing dry Chlorine into liquid Terchloride of Phosphorus, an Oxychloride of Phosphorus, PC1 3 0, is made by heating Chloride of Phosphorus with a quantity of Water insufficient to convert it into Phosphoric Acid. 2452. Hydride of Phosphorus, PH 3 , or Phosphoretted Hydrogen, is an explosive gas made by boiling Phosphorus with Milk of Lime, as in making Hypophosphorus Acid. It has a very disagreeable smell. 2453. Oxides of Phosphorus. — With Oxygen, Phosphorus forms three Oxides, Phosphoric Oxide, P 2 5 , Phosphorus Oxide, P 2 3 , and Hypophos- phorus Oxide, P 2 0. 2454. Acids of Phosphorus. — The more important of these Acids have been already described. (34, 42, 43.) Orthophosphoric Acid, H 3 P0 4 (tribasic), is made by dissolving Phosphoric Oxide in water, or by the action of Nitric Acid on Phosphorus. The 50 per cent, solution is the U. S. official Phosphoric Acid. The salts made by com- bining this Acid with bases are called Phosphates. Pyrophosphoric Acid, H 4 P 2 0, by heating Orthophosphoric Acid to 2i3°C. (41 5.4 F.). Metaphosphoric Acid by igniting tribasic Phosphoric Acid or by dissolving P 2 5 in cold water. These three Acids correspond with the Oxides above mentioned. PICROTOXINU M — PICROTOXIN. PILULE — PILLS. 675 Phosphorous Acid, H 3 P0 3 , cannot be formed directly from Phosphorus Oxide but is a dibasic Acid, containing one hydrogen atom that cannot be replaced by a metal. The salts of this Acid are called Phosphites. Hypophosphorus Acid, H 3 P0 2 , cannot be made directly from Hypophos- phorous Oxide. It contains two hydrogen atoms not replaceable by a metal. It is the acid basis of the Hypophosphite salts. 2455. PICROTOXINUM — PICROTOXIN. C 9 H 10 O 4- A neutral principle prepared from the seeds of Anamirta Paniculata — the kernel of Cocculus Indicus — by exhausting with hot water, evaporating to an extract, mixing the extract with Magnesia, then treating with hot Alcohol, filtering through animal charcoal, concentrating by evaporation, and crystallizing. Uses. — This is used as an antispasmodic and nerve tonic, like Strychnine, in doses of jfo to -^ grain. PILULE — PILLS. Since the general introduction of sugar and gelatine-coated pills, their manufacture has been almost entirely monopolized by manufacturing houses. The pill business has come to be a great nuisance to druggists, for the reason that so many manu- facturers urge their claims for superiority upon the physicians, that a large stock of many different makes must be kept on hand in order to supply the demand. It is not only unprofitable, but very annoying to be obliged ep so many manufacturers' pills on hand, but as yet there seems to be no way of avoiding it. '1 he pills that are included iri the Pharmacopoeia constitute but a very small portion of those in use, and as manufacturers' pills are nearly always coated with sugar or gelatine, it maybe said that scarcel)' any pills made by the Pharmacopoeia formula} are dispensed by druggists. 676 PILUL.L — PILLS. The making and coating of pills to any great extent is impracticable for the mass of druggists, because it requires considerable apparatus and some experience and skill ; and further, because there are so few of any but the leading or special pills used that it does not pay to make the small quan- tity required for the retail trade. Many druggists, however, prefer to make their own pills as a matter of reliability. We give, therefore, the general processes for making and coating pills, and such formulae as may seem expedient for those who wish to prepare their own pills. The recent introduction of reliable powdered extracts of American manufacture, has very much simplified the making of pills, as the ingredients may be readily and accurately mixed before combining into a pill mass. Many of the old solid extracts were very difficult to work evenly into a pill mass, and required much preparation before they were ready for use. This is now happily done away with by the introduction of powdered extracts of all dangerous drugs, and by the use of which a thorough distribution of the medicinal agents may be secured. Not only are the powdered extracts better on this account, but the mass can be much more readily prepared ; as, with the old solid extracts it was often necessary to soften them, so that an extra amount of drier had afterwards to be used, which increased the bulk of the pill. Small pills are now the fash- ion in medicine, and a pill without some kind of coating is looked upon with great disgust by the great American stom- ach. Upon the nicety of the pill depends the nicety with which it can be coated, so we will first consider the pill itself, and afterwards its outer covering. This is the reverse of the view taken by the pill-taker, as he usually is more concerned as to the character of the covering than the character of the pill ; but the pill-maker and the pill-taker can hardly be ex- pected to take the same view of the subject. The directions which follow are intended for the use of the ordinary druggists, with such conveniences as they all have, to make and coat pills in small quantities, suitable for the retail .trade, and for extemporaneous and prescription business. PILULE — PILLS. 677 Conveniences for Pill Making. Pill Mac/ilnes are only adapted to making certain sizes of pills. For the manufacturer who is making large quantities of certain sizes they are a great assistance, but for the retail druggist but little use can be made of them. Those who have them can use them for such sizes as their material will prop- erly make, but it is hardly advisable for those who do not have them to buy them, as there are so few pills for which they can be used. Materials vary so much that it is almost impossible for the druggist to so regulate the mass as to get the desired amount of material in each pill, when working with a machine. Take, for instance, Calomel and Quinine, a two-grain pill of one would be much smaller than a two-grain pill of the other, but the pill machine would make them both of the same size. They are very convenient for marking and dividing the pill, and those who have them can use them for that purpose, but a simple, inexpensive pill marker and divider is more service- able. The ordinary pill tile will answer every purpose. This, with a pill roller, a pill rounder, and the ordinary mortars and pestles completes the necessary outfit for ordinary pill making, and experience does the rest. The Excipients. Many Excipients have been proposed for making pills, with which druggists are already familiar, as mucilage, syrup, glu- cose, honey, soap, glycerin, etc., and all of them have their uses, but nothing has been found so good for general purposes as the Starch Plasma, or, as we shall call it here, Excipient. It is tenacious without being elastic, readily mixable, free from odor or objectionable taste, does not mould or spoil, keeps without change, keeps the pills soft and pliable, is inex- pensive, and readily made as follows: 2456 Excipient. Starch, in fine powder, 1 drachm. Glycerin, by weight 1 ounce. 678 PILUL/E — PILLS. Mix and heat, with constant stirring, to boiling (240 F.), or until it has assumed a uniform gelatinous mass. Too high a degree of heat must not be used, as it will burn the Starch on the bottom, and it must be constantly stirred to prevent this result. It can be made best on a sand-bath. In making pills with this Excipient, use only a small quan- tity, well worked in with the pestle, and then if more is required it may be added. The Driers. The chief use of the Drier is to dust the tile and roller and the pills after they are made, to prevent sticking together. It is also sometimes necessary to use it with the mass when the extracts used are too soft or when oils or other liquids enter into the composition. A great many substances are used as Driers, as Powdered Liquorice Root, Lycopodium, Flour, Starch, etc., but the best dryer to meet all the requirements for which it is needed, is made thus : 2457. Drier. Starch, in very fine powder, ) , , . , - - equal parts, mixed. Elm Bark, in very fine powder, 1 This will be found much better than powdered Liquorice, Lycopodium, or other substances usually used for this purpose. Finely powdered Starch or Wheat Flour alone is better for white pills than the above Drier, as it does not color them. Dextrine also makes a good Drier for colored pills. They are best applied as a dusting, with an ordinary salt sprinkler or pepper-box, such as are used on the dining table. This completes the list of requisites for making pills, except, of course, the drugs that enter into their composition. Making Pills. The Mass should always be made in a mortar, propor- tionate to the amount required, and with a long-handled PILULE — PILLS. 679 pestle, not too large. It is best to observe the following order in making the mass, so as to secure the best results in the least time. First. — Reduce all crystals or pulverizable masses to a very fine powder by rubbing in the mortar. Powerful drugs like Strychnine, Atropia, Morphia, etc., should be mixed with a small quantity of Sugar of Milk in powdering, so as to secure a thorough distribution of their particles. When the crystals or other drugs are thoroughly powdered, add any powdered extracts, resinoids, or other powdered drugs that may be directed, and mix thoroughly and intimately in the mortar. Second. — Add any solid extracts, confections or other masses that may be directed, taking great care to have them in such condition that they can be readily worked up with the other ingredients. Most extracts can be softened by warming a little ; some require a little Water or Alcohol. Mix these thoroughly with the powders in the mortar by working them in with the pestle. When this is done, if it requires to be softened (which is generally the case), add enough of the Excipient to make into a pilular mass, or, if too soft, add enough of the Drier to harden it. In using the Excipient but a small amount isjiecessary, but it must be well worked in. Never add Alcohol, Water, or Syrup to a pill mass if it can be avoided. If any oils are directed in the formula, they should be mixed in a mortar with the Excipient before it is added to the mass. They are thus emulsified and the oily particles broken up, so that a thorough distribution is effected. Do not add oils to the powders in the mortar, as a portion of the powder absorbs the oil and the distribution is much retarded. It is also much more difficult to work the mass than when the oils are first combined with the Excipient. If two much Excipient has been used, Drier may be added to bring it to the requisite temper, but it is better to be care- ful and not add too much, as the Drier increases the bulk and size of the pill. 680 PILULE — PILLS. The Pill. Having now prepared the mass, the Pill is next in order. First. — Weigh the mass carefully and then (if for more than 24 Pills) divide it into portions that will make as many Pills as the Pill machine, tile, or divider indicates — 12, 18 or 24 is the usual number. For instance, if 100 Pills are to be made, and the whole mass weighs 316 grains, each Pill will be 3.16 grains. If the Pill tile, divider or machine is marked for 18 Pills, 3.16x18=56.88, or 57 grains, should be the weight of each portion, and you will have as many portions as 18 is con- tained in 100, or 5^ portions. Second. — Dust the tile or machine with the drier, and roll each portion out to the length indicated for the number of Pills. Several portions may be rolled out together at the same time, side by side, if the mass is of proper consistence, and drier is properly used. They should be rolled evenly from end to end, with a slanting motion of the roller. When rolled to the proper length, divide as indicated by the tile, divider or machine, and roll into Pills. Complete the rolling at last by rolling the rounded Pills gently with a circu- lar motion of the roller on the slab. Put in a shallow tin, or other convenient dish, in a cool place to harden. A jelly-cake tin is very convenient for this purpose. A scale pan may also be used. The Pills, thus prepared, are ready for coating. Coating Pills. Pills are coated chiefly to render them tasteless while being taken ; but the coating serves the further important office of protecting them from the atmosphere. Sugar Coating. — The apparatus for coating Pills advan- tageously with sugar is quite expensive, and the experience required to coat them artistically is considerable. They may, however, be coated in a small way by revolving the Pills after they are made in a little albumen or mucilage, to give them a thin coating, then transferring to another dish, dusting them well with finely powdered sugar, and rolling them in a shallow evaporating dish, thus giving them an even coating. PILULE — PILLS. 681 This method is only used for extemporaneous work. To coat Pills with sugar as they are found in the market requires large copper revolving globes, of which the upper third is cut off, and which are revolved at an angle (the same as are used by confectioners). The best apparatus of this sort is also ar- ranged for an oscillating motion, which prevents the Pills from adhering to the side. They are also arranged with heating apparatus, so that the heat may be maintained at any desired degree. The Pills are first partially dried, then coated over with Tincture of Tolu or a Solution of Shellac. Then put in the coating apparatus, add a little syrup of white sugar and a sprinkling of starch from time to time, while the globe is slowly revolved, a very moderate heat being applied at the same time, until the coating is of sufficient thickness. To give a finish or polish to the Pills after they are coated, they are agitated in the coater with a few lumps of paraffine or wax. It is obvious that small quantities of Pills cannot be conveniently sugar- coated in this manner. It will thus be seen that sugar-coating Pills as they are found in the market requires expensive machinery, experience and time, which are not at the disposal of the ordinary drug- gist in his business. Gelatine Coating. — Pills may be coated with Gelatine by sticking them on pins and dipping them in a Solution of Gela- tine, etc., heated sufficiently to keep it liquid, then revolving them in the air until the coating is sufficiently set so that the Pills will not adhere when put together. The solution for Gelatine or Soluble Coating may be made as follows : 2458. Gelatine Coating. Best White Gelatine, Cooper's, Cox's, or French, I ounce av. Water, 4 fl. ounces. Dissolve the Gelatine in the water, by heat of water- bath, and strain through a tin strainer or a sieve into a water- bath, which must be kept warm, adding a trifle of warm water 682 PILUL.E — PILLS. occasionally to make up for the evaporation. Dip the Pills in the Solution quickly, and revolve in the air until dry. 2459. Gelacacia or Soluble Coating. Gelatin, best white 1 ounce av. Gum Arabic, select, ]/ 2 ounce av. Glycerin, % ounce av. Water, 4^ ounces av. Dissolve the Gum Arabic in 2 ounces of the Water by allowing to stand over night, add this to the Gelatin and bal- ance of the Water and Glycerin and heat to dissolve the Gel- atin. W T hen dissolved strain and keep warm with a water-bath while using. The pills, stuck on pins or needles, are to be dipped into the solution and dried by revolving in the air. This makes the best and smoothest coating for pills. It may with propriety be called Gelatin Coating. Apparatus of various kinds may be obtained for Gelatin-Coating pill, but without experience it proves generally unsatisfactory in the hands of druggists. Pills may also be coated with a solution of Shellac, 90 grains to 1 ounce of Alcohol, which does very well for extemporane- ous work. They may be dipped in the solution or revolved in an evaporating dish with a very small quantity of it. 2460. Silvering and Gilding Pills. Pills are sometimes coated with silver or gold leaf. This is done simply by moistening the pills with a thin coating of Albumen or Acacia solution and then revolving in a small globe in which leaves of silver or gold have been placed. The process is familiar to most druggists and many already have the small globes for silvering or gilding. Besides the substances already mentioned for coating pills, French Chalk or Starch are sometimes used, the pills being first rolled in a solution of Acacia and then transferred to another dish containing the coating substance, which adheres sufficiently for the purpose. Paraffin and Cacao Butter are also used for coating pills. PILULE — PILLS. 683 Formulae for Pills. In the formulae which follow it is not intended to give work- ing formulas for definite quantities of Pills, but only the com- position of those most used, with such hints as may be neces- sary for making them. The composition is mostly given for one Pill only, and it is obvious that any number may be cal- culated by multiplying the ingredients of the formula by the number of Pills desired. 2463. Abernethy's Pills. — Aloes Socotrine, Extract Hyoscyamus, each 2 grains, Pill Hydrarg., 1 grain, Ipecac f grain. 2464. Aconitine Pills. — (Amor- phus) are made y£^ and ^ grain, each with Extract Gentian as an excipient. 2465. Aconitine Pills (Dequesnels Crystallized), are made 5^ to^J-^ grain each, with Extract Gentian as an ex- cipient. 2466. Aconite Extract Pills. — These may be made %, % or 1 grain, or to contain x /% to l / z minim of Tincture of Aconite in each. 2467. Aloes Pills.— The U. S. for- mula is equal parts of purified Aloes and Soap, to make a 4-grain Pill. The Br. P. directs these to be made both from Barbadoes and Socotrine Aloes, contain- ing about one-half Aloes, one-fourth each Soap and Confection of Roses, anil .,'., part Oil of Caraway. 2468. Aloes and Asafetida Pills. — The U. S. P. directs purified Aloes, Asafetida and Soap, each l 1 /^ grains. The Br. P. directs the same propor- tions, with the addition of about the same quantity of Confection of Roses, the dose being 5 to 10 grains. 2469 Aloes and Iron Pills.— The U. S. P. directs purified Aloes, dried Sulphate of Iron and Aromatic Powder, each one grain, with sufficient Confection of Roses to make a mass. The Br. formula is Sulphate of Iron 1%. part, Barbadoes Aloes 2 parts, Compound Powder of Cinnamon 3 parts, Confec- tion of Roses 4 parts, the dose being 5 to 10 grains. Some manufacturers add l / 2 grain Extract Conium to each Pill. 2470. Aloes and Mastic — Lady Webster's Dinner Pill. — Purified Aloes 2 grains, Mastic, Red Rose, each )/ z grain in each Pill. This is a favorite Dinner Pill. 2471. Aloes and Myrrh Pills — The U. S. formula is purified Aloes 2 grains, Myrrh 1 grain, Aromatic Pow- der ^ grain, mixed with syrup, in each pill. The Br. is about the same. 2472. Aloes, Myrrh and Iron Pills. — Socotrine Aloes, Myrrh, each 2 grains, dried Sulphate of Iron 1 grain, in each pill. 2473. Aloes and Nux Vomica Pills. — Socotrine Aloes i]/ z grains, Extract Nux Vomica )4 grain, in each pill. 2474. Aloes, Nux Vomica and Belladonna Pills.— Add ; s urain Ex- tract of Belladonna to the former for- mula. 2475. Aloin Pills.— These Pills are made , * grain, 2 grain, ^ on grain of Aloin in each, with Extract of Gentian as an excipient. 2476. Aloin Compound Pills. — Aloin 'yn j^rain, Podophyllum Js grain, Extract Belladonna ){ grain, in each 684 PILULE — PILLS. pill. Many other compounds are made with Aloin and Podophyllin. 2477. Aloin and Strychnine Pills. — Aloin I grain, Strychnine ■£$ grain, with Extract Gentian as an excipient. 2478. Aloin, Strychnine and Bel- ladonna Pills. — Add }i grain Extract of Belladonna to each pill, made as the preceding. 2479. Alterative Pills. — Ipecac, Opium, each y$ grain, Pill Hydrag. (Blue Mass), 1 grain in each pill. 2480. Anderson's (Scot's) Pills. — These are generally prepared in this country from Aloes 24 parts, Castile Soap 4 parts, Colocynth and Gamboge, each 1 part, Oil Anise %, part, made into 3 grain pills. 2481. Anti-bilious Pills— Com- pound Extract of Colocynth 2^ grains, Podophyllin % grain in each. Many other similar formulas may be used. 2482. Anti-Constipation Pills. — Juglandin, Leptandrin, each % grain, Extract Henbane )/% grain, Strychnine j-jj^ grain, in each pill. 2483. Anti-Chill Pills.— Chinoidin 1 grain, Oleo-resin, Black Pepper, 1 grain, Ferrocyanide of Iron 2 grains, Arsenious Acid -£§ grain in each. Many other similar formulas may be used. 2484. Anti-Dyspeptic Pills. — Strychnine -£$ grain, Extract Belladon- na, Ipecac, each ^ grain, Blue Mass, Extract Colocynth Compound, each 2 grains in each pill. 2485. Anti-Periodic Pills.— Sul- phate Cinchonidine I grain, Sulphate Iron ^ grain, Podophyllin, Gelsemin, each 4ts grain, Strychnia -^ grain, Oil Capsicum -fa drop, in each pill. 2486. Anti-Malarial Pills.— Sul- phate Quinine 1 grain, Sulphate Cin- chonidine 1 grain, Arsenious Acid ^ grain, Carbolic Acid % grain, Oil Pep- permint }i grain, Capsicum % grain, in each pill. 2487. Anthelmintic Pills.— Santo- nine, Calomel, each 1 grain in each pill, with confection Senna as an excip- ient. 2488. Aperient Pills.— Extract Col- ocynth Compound 2 grains, Extract Nux Vomica ^ grain, Extract Hyoscy- amus x / z grain in each pill. Many other pills may be put up under this name. 2489. Aphrodisiac Pills. — Extract Damiana 2 grains, Extract Nux Vomica y$ grain, Phosphorus y^ grain, in each pill 2490. Arsenious Acid Pills. — These pills are made -£$, -^, -£$, and ■£$ grain, with Excipient or Extract Gen- tian in each pill. Iodide of Arsenic and other salts of Arsenic are made generally about -g^ grain in each pill. 2491. Asafetida Pills. — Asafetida, in powder \ x / 2 grain, Castile Soap ^ grain in each, well rubbed together to form a mass. This makes a 2-grain pill. Double the quantities for 4-grain pill. Asafetida Pills should be well coated with Tolu or Shellac. 2492. Asafetida Pills Compound, or Compound Galbanum Pills.— The Br. P. directs Asafetida, Galbanum, Myrrh, each 2 parts, Treacle 1 part to make a mass, of which 5 to 10 grains is a dose. 2493. Asafetida and Iron Pills. — Asafetida 2 grains, dried .Sulphate of Iron 1 grain, in each pill. 2494. Asafetida and Nux Vomica Pills.— Asafetida 3 grains, Extract Nux Vomica ^ grain, in each pill. 2495. Atropine Pills.— These are made to contain j^, j^q, or ■£$ grain of Atropine with Excipient or Extract Gentian in each. 2496. Belladonna Extract Pills. — Pills of Extract of Belladonna are PILULE — PILLS. 685 made -J v , yi, ]i, and ^ grain, in each pill. 2497. Bismuth Subnitrate Pills. These pills are made 3 or 5 grains, with excipient, in each pill. Subcarbonate of Bismuth is also made into pills the same quantity. 2498. Bismuth and Nux Vomica Pills. — Bismuth 2^ grains, Extract Nux Vomica % grain, in each pill. 2499. Bromide of Ammonium, Bromide of Potassium, and Bro- mide of Sodium Pills are made 5 grains in each pill, but they are much more desirable in the form of elixirs or solutions. 2500. Blue Pill or Pill Hydrarg. — This mass is made up into pills y z grain, 1 grain, 3 grains, and 5 grains each. 2501. Blue Pill Compound. — Blue Mass 1 grain, Opium l / 2 grain, Ipecac % grain, in each pill. 2502. Caffeine Citrate Pills.— Cit- rate of Caffeine 1 grain, with excipient in each Pill. 2503. Calcium Sulphide Pills. — These Pills are made to mask the dis- agreeable odor of this salt. \(j,%,y2,l, 2 and 3 grains, each with excipient. 2504. Calomel Pills.— Pills of Cal- omel are made fVi i. 1 > 2 > 3 an< 3 5 grains, each with excipient. 2505. Calomel Compound Pills. — Compound Pills of Antimony, Plutn- vur's Pills. — The U. S. formula is Sulphurated Antimony, Calomel each \ grain, Resin Guaiac 1 grain, in each pill. The Br., Till contains Castor Oil also. 2506. Calomel, Nux Vomica and Podophyllin Pills. — Calomel 1 grain, Extract Nux Vomica ^ grain, l'odo- phyllin y z grain, in each pill. 2507. Calomel and Opium Pills. — Calomel 2 grains, Opium 1 grain, in each pill. 2508. Calomel and Rhubarb Pills. — Calomel •/ grain, Extract Rhubarb, Compound Extract Colocynth, each % grain, Extract Hyoscyamus l /e grain, in each pill. 2509. Camphor Compound Pills. — Camphor, Opium, Kino, each 1 grain, Capsicum -^ grain, in each pill. 2510. Camphor Hyoscyamus Pills. — Camphor, Extract Henbane, each 1 grain, in each pill. 251 1. Camphor, Hyoscyamus and Valerian Pills. — Camphor, Henbane Extract, each 1 grain, Extract Valerian j4 grain, in each pill. 2512. Camphor Monobromated Pills. — These Pills are made with 2 grains, 3 grains or 5 grains of mono- bromated Camphor, in each Pill. 2513. Camphor and Opium Pills. — Camphor 2 grains, Opium 1 grain, in each pill. 2514. Camphor, Opium and Tan- nin Pills. — Camphor i%. grains, Opium, Tannin, each ^5 grains, in each pill. 2515. Cannabis Indica Extract Pills. — These are made %, % and 1 grain of the Extract in each pill. 2516. Capsicum Pills. — Capsicum 1 grain, with Extract Gentian as an ex- cipient in each pill. 2517. Cascara Sagrada Extract. — Cascara Sagrada Extract 2 grains, in each pill. 2518. Cathartic Compound Pills. — The U. S. formulu is Compound Ex- tract of Colocynth 130 grains, Abstract of Jalap 100 grains, Mild Chloride of Mercury ioograins, Gamboge 25 grains, to make 100 pills. 2519. Cathartic Compound Pills. — Active. — Calomel, Powdered Extract Colocynth Compound, Gamboge, Cas- tile Soap, each '/$ grain, Ipecac, j- grain, Socotrine Aloes }4 grain, Rhubarb % PILULE — PILLS. grain. Capsicum, Podophyllin each y 1 ^ grain, in each pill. 2520. Cathartic Compound Pills. — Mild. — Calomel % grain, Colocynth Compound % grain, Ipecac ]/(, grain, Gamboge, Socotrine Aloes, Rhubarb, Capsicum, Castile Soap, each ]A, grain, Podophyllin 4$ grain, in each pill. 2521. Cathartic Compound Im- proved Pills. — Extract Colocynth Com- pound 1 grain, Extract Jalap yl grain, Resin Podophyllin y$ grain, Resin Lep- tandrin y% grains, Extract Hyoscya- mus % grain, Extract Gentian % grain, Oil Peppermint ^ minim, in each pill. Several other similar formulas are in use. 2522. Cathartic Vegetable Pills. — j Grains. — Compound Extract Colo- cynth i]4. grains, Podophyllin y$ grain, Leptandrin % grain, Extract Jalap % grain, Socotrine Aloes % grain, Extract Hyoscyamus % grain, Oil Peppermint t^jj minim, in each pill. 2523. Cerium Oxalate Pills.— These are made 1, 2 or 3 grains, with Excipient or Extract of Gentian in each pill. 2524. Charcoal Pills.— Willow Charcoal 3 grains in each. 2525. Chinoidin Pills.— These are made )4, 1, 2, 3 or 5 grains of purified Chinoidin in each. 2526. Chinoidin Compound Pills. — Chinoidin 2 grains, Iron 1 grain, Piperin }4 grain, in each pill. 2527. Cinchona Bark Alkaloids Pills. — Sulphate of Quinine, Sulphate of Quinidine, Sulphate of Cinchonine, Sulphate of Cinchonidine, each % grain, in each pill made in a mass with excipient. 2528. Cinchonine Sulphate Pills. — These are made iyi, 2, 3 and 5 grains in each, with excipient. 2529. Cinchonidine Sulphate Plils. — These are made 1, 2, 3, 4 and 5 grains in each pill, with excipient. 2530. Coca Extract Pills. — These are made 1, 2, or 3 grains of the Ex- tract in each pill. 2531. Cocaine Pills. — These are made of the alkaloid and also of the hydrochlorate, %, %, and 1 grain in each pill. 2532. Codeine Pills. — These are made y 1 ^, yi, %, and % grain of the alkaloid with Extract of Gentian as an excipient in each pill. 2533. Colocynth Compound Ex- tract Pills. — These are made 3 grains of the extract in each pill. 2534. Colocynth Compound Pills. — The Br. P. directs Colocynth Pulp 4 parts, Barbadoes Aloes 8 parts, Resin of Scammony 8 parts, Sulphate of Pot- assium 1 part, Oil of Cloves 1 part, to be mixed and beat into a mass, of which 5 to 10 grains is the dose. Man- ufacturers furnish 4 and 5 grain pills of this composition. 2535. Colocynth Compound and Blue Mass Pills. — Extract Colocynth Compound 3 grains, Blue Mass 2 grains, in each pill. 2536. Colocynth, Ipecac and Blue Pills. — Blue Mass, Extract Colocynth Compound, each 2 grains, Ipecac ]/(, grain, in each pill. 2537. Colocynth and Hyoscyamus Pill.— The Br. P. directs Colocynth Compound Pill 2 parts, Extract of Hy- oscyamus 1 part, to be made into a mass, of which the dose is 5 to 10 grains. 2538. Colocynth and Podophyllin Pill. — Compound Extract of Colo- cynth iy 2 grains, Resin of PodophyLin % grain, in each pill. 2539. Colocynth, Hyoscyamus, and Blue Mass Pills. — Compound Extract of Colocynth 3 grains, Extract PILULE — PILLS. 687 Hyoscyamus, Blue Mass, each i grain in each pill. 2540. Colocynth, Nux Vomica, and Belladonna Pills. — Compound Extract of Colocynth 2 grains, Extract Nux Vomica %. grain, Extract Bella- donna -^j grain, in each pill. 2541. Conium Extract Pills. — Extract of Conium j4 grain, 1 or 2 grains, in each pill. 2542. Conium Compound Pills. — The Br. P. directs Conium Extract 5 parts, Ipecac 1 part, to be made into a mass with Treacle, of which the dose is 5 to 10 grains. 2543. Cook's Pills. — Rhubarb, Aloes, each 1 grain, Calomel ^ grain, Soap % g ra i n > m eacn Pil'- 2544. Copaiba Pills. — Solidified Copaiba is made up into pills of 3 grains each. 2545. Copaiba and Cubebs Pills. — Solidified Copaiba 2 parts and Oleo- resin Cubeb 1 part is made up into pills of 3 to 5 grains each. It is necessary to use some drier, as Magnesia, in mak- ing this pill. 2546. Copaiba Compound Pills. — Pill Copaiba, Resin Guaiac, each 1% grain, Citrate Iron, Oleo-resin Cubebs, each y 2 grain, in each pill. 2547. Corrosive Sublimate Pills. — These may be made T J ff , T V. in, tV- or yi grain of the salts, with Extract Gentian, in each pill. 2548. Croton Oil Pills.— Croton Oil y 2 grain, Wheat Flour i l / 2 grain in each pill, with excipient or some extract. 2549. Cubebs and Alum Pills.— Extract Cubebs 2 grains, Alum 1 grain, in each pill. 2550. Cubebs, Rhatany, and Iron Pills.— Kxtract Cubebs i l / 2 grains, Extract Rhatany */ 2 grain, Sulphate of Iron, 1 grain, in each pill. 2551. Damiana Extract Pills. — These are made 3 to 5 grains of the extract in each pill. 2552. Damiana and Phosphorus Compound Pills. — Extract Damiana 2 grains, Extract Nux Vomica )/% grain, Phosphorus y-J-g- grain, in each pill. 2553. Digitalin Pills. — Digitalin ■g 1 ^ grain in each pill with Extract of Gentian as excipient. 2554. Digitalis Extract Pills. — Digitalis Extract y z grain in each pill. 2555. Digitalis Compound Pills. — Digitalis, Squills, each 1 grain, Ni- trate Potassium 2 grains, in each pill. 2556. Dinner Pills (Chapman's). — Aloes, Mastic, each 1%. grain, Ipecac 1 grain, Oil Fennel -fe grain, in each pill. 2557. Dinner Pills (Cole's). — Blue Pill, Aloes, Jalap, each 1^ grains, Tar- tar Emetic ^j grain, in each pill. 2558. Dinner Pill (Dr. Hall's)— Aires Pill Dihde. — Aloes, Liquorice, Soap, and Theriaca, each 1 grain in each pill. 2559. Dinner Pill (Lady Web- ster's). — Aloes 2 grains, Mastic % grain, Rose Leaves yi grain, beat together, in each pill. 2560. Diuretic Pills.— Extract of Buchu, Nitrate of Potassium, each 1 grain, Squill j4 grain, in each pill. 2561. Elaterium Pills (Clutter- buck's). — These are made - 3 J to -fa grain each of Elaterium with Extract Gentian as an excipient. 2562. Elaterin Pills.— These are prepared ,,',,, to „'„ grain of the neutral principle Elaterin in each pill with Ex- tract Gentian as an excipient. 2563. Emmenangogue Pills.— I'.r- gotin, Extract Cotton Root, Aloes, Iron, each 1 grain, Oil Savin ^ grain, in each pill. 2564. Ergotin Pills. — These are made with Ergotin 1, 2, or 3 grains in PILUL/E — PILLS. each pill. One grain of Ergotin equals 10 grains of Ergot. 2565. Ergotin Compound Pills (Dr. C. Godson's). — Ergotin 3 grains, Extract Cannabis Indica }/(, grain, Strychnine u ^ grain, in each pill. 2566. Eucalyptus Extract Pills. — These are made 2 to 4 grains in each pill. 2567. Extract Pills. — Any extract can be made up into pills as desired, the quantity in the pill being regulated according to the medium dose usually given of the extract. 2568. Ferruginous Pills (Blaud's Pills). — Sulphate of Iron, dried, Car- bonate of Potassium, each in equal quantities, made into a mass with pow- dered Tragacanth, \)/ 2 or 2^ grains each of the Iron and Potassium, in each pill. 2569. Gelsemium Extract Pills. — These are made 1 grain each of Gelse- mium Extract. Gelsemin Pills are made j4 grain with Extract Gentian excipient. 2570. Gentian Extract Compound Pills. — Extract Gentian, Aloes, each 7^ grain, Rhubarb 1^3 grain, in each pill. 2571. Gonorrhoea Pills. — Cubebs 2 grains, Pill Copaiba 1 grain, Sulphate Iron Exsic. x / 2 grain, Venice Turpen- tine 1% grain, in each pill. 2572. Grindelia Robusta Extract Pills. — These are made 3 grains Ex- tract Grindelia, in each pill. 2573. Guarana Extract Pills.— Extract of Guarana or Paullinia 1 or 3 grains in each pill. 2574. Helonias Compound Pill.— Helonias x /% grain, Caullophyllin j^f grain, Vibernin y% grain, Extract Mitchella \*4. grain, in each pill. 2575. Hepatic Pills.— Blue Pill 3 grains, Extract Colocynth Compound 2 grains, Extract Belladonna % grain. 2576. Hooper's Pills.— Barbadoes Aloes 1 grain, Sulphate Iron Exsic. y i grain, Extract Hellebore, Gum Myrrh, Castile Soap, each )i grain, Jamaica Ginger l /% grain, Canella Alba l /% grain in each pill. 2 577- Hydrastine Pills. — These are made y or 1 grain each of the white Alkaloid. 2578. Hyoscyamus Extract Pills. — Extract of Hyoscyamus ^ on grain in each pill. Hyoscyamine (resinoid) Pills are made y grain in each pill. Hyoscyamine (alkaloid) Pills are made ^ and x^ grain and -^ grain in each pill. 2579. Hypophosphites Compound Pills. — Hypophosphite of Lime 1 grain, Hypophosphite of Soda y grain, Hypo- phosphite of Potassium y z grain, Hypo- phosphite of Iron y grain, Extract Gen- tian )/ 2 grain, in each pill. 2580. Iodoform Pills. — Iodoform 1 grain with Extract of Gentian y z grain as an excipient in each pill. 2581. Iodoform and Iron Pills. — Iodoform, Iron by Hydrogen each 1 grain with Extract of Gentian as an ex- cipient in each pill. 2582. Iodoform, Iron and Quinine Pills. — Iodoform 1 grain, Protocarb. Iron 2 grains, Quinine Sulph. y 2 grain in each pill. Other combinations of Iodoform are made with Opium, Nux Vomica, etc. 2583. Ipecac Pills. — Ipecac %, y, or 1 grain in each pill with excipient. 2584. Ipecac and Opium Pills, Dover s Pills. — Dover's Powder 1 grain, iy 2 grains and 5 grains each in each pill. A Pill of Ipecac and Opium in which 2 grains represent the active ingredients of 5 grains of Dover's Powder may be made with Opium and Ipecac, each y grain, Sulphate of Potassium 1 grain, in each pill. PILUL.E — PILLS. 2585. Ipecac and Hyoscyamus Pills. — Ipecac, Extract Hyoscyamus, each 1 grain, in each pill. 2586. Ipecac and Squill Pills. — Dover's Powder 3 grains, Squill, Ammo- niac, each 1 grain, with Theriaca as an excipient. This is official in the Br. P. 2587. Irisin Compound Pills.— Irisin % grain, Podophyllin j f) - grain, Strychnine £$ grain, in each pill. 2588. Iron by Hydrogen Pills (Quevenne's Pills). — These are made 1 grain, 2 grains or 4 grains of Iron by Hydrogen in each pill, with Ext. Gen- tian as excipient. 2589. Iron Bromide Pills. — Brom- ide of Iron 3 grains, with Extract Gen- tian as excipient in each pill. 2590. Iron Citrate Pills.— These are made 2 or 3 grains of Citrate of Iron (not Citrate of Iron and Ammo- nium) in each pill. 2591. Iron Citrate and Cincho- nidine Pills. — Citrate of Iron 1 y 2 grain, Cinchonidine Sulph. y 2 grain, in each pill. These pills are also made 3, 4 or 5 grains in the same proportion. 2592. Iron Citrate and Quinine Pills. — These are made 1, 2, 3, 4 and 5 grains of Citrate of Iron and Quinine in each pill. 2593. Iron Citrate and Strych- nine Pills. — Citrate of Iron 1 grain, Strychnine ..',, grain, in each pill. 2594. Iron Citrate, Quinine and Strychnine Pills. — Citrate of Iron and Quinine 1 grain, Strychnine - 1 ,, grain, in each pill. 2595. Iron Ferrocyanide Pills.— Ferrocyanide of Iron 3 grains with Ext. m as excipient in each pill, 2596. Iron Iodide Pills.— Blanch- artfi I 'ills. — These are made t grain of Iodide of Iron in each pill, with Extract < rentian as excipient. 2597. Iron Lactate Pills. — Lac- tate of Iron 1 grain in each pill, with Extract Gentian as excipient. 2598. Iron Phosphate Pills. — Phosphate of Iron 1, 2, 3 or 5 grains, in each pill. Many Compounds of Phosphate of Iron with other salts and substances are made in the same proportion as com- binations of Citrate of Iron. 2599. Iron Proto-Carbonate Pills. — Vallefs Pills — These are made of Vallet's Mass, 2, 3 or 5 grains. The Br. Official Formula for Pill of Carbon- ate of Iron is Saccharated Carbonate of Iron 4 parts, Confection of Roses 1 part. 2600. Iron Sulphate Exsiccated Pills. — These are made from dried Sulphate of Iron 4 grains, with Extract of Gentian as excipient, in each pill. 2601. Iron Valerianate Pills. — Valerianate of Iron 1 grain in each pill, with Extract Gentian as excipient. 2602. Jaborandi Extract Pills. — These are made 3 grains of Extract of Jaborandi in each pill. 2603. Jalap Extract Pills.— Ex- tract of Jalap 1 grain in each pill. 2604. Laxative Pills. — Rhubarb 1 grain, Castile Soap }( grain, Socotrine Aloes, y z grain, Myrrh '/$ grain, Ipecac ,'.. grain, Bircarb. Soda l / z grain, Oil Anise -, 1 ., minim, in each pill. 2605. Leptandrin Pills. — These are made %., 1 or 2 grains of Resin Leptandrin in each pill. 2606. Leptandrin Compound Pills. — Leptandrin 1 grain, Irisin % grain, I'odophyllin ' ,' grain, in each pill. 2607. Lupulin Pills. — These are made 3 grains of Lupulin in each pill. 2608. Lupulin and Camphor Pills. — Lupulin 1 grain, Camphor 1J2 grains, in each pill. 690 PILUL.E — PILLS. 2609. Lupulin and Lettuce Pills. — Lupulin 1 grain, Extract of Lettuce 2 grains, in each pill. 2610. Mandrake Extract Pills. — These are made 1 grain of Extract of Mandrake in each pill. 261 1. Mercurial or Blue Pill. — Br. Blue Mass — is made with Mercury 2 parts, Confection of Roses 3 parts, Liquorice Root 1 part. Rub the Mer- cury with the Confection of Roses until Globules of Mercury are no longer vis- ible, then add the Liquorice and mix the whole well together. 2612. Mercury Bin-Iodide Pills.— These are made with Red Iodide of Mercury j^, £g or ^ grain in each pill, with Extract Gentian as an excipient. 2613. Mercury Cyanide Pills. — Cyanide of Mercury ^ grain in each pill. 2614. Mercury Proto-Iodide Pills. — These are made yi, A, %, y 3 , and l /-, grain of Green Iodide of Mercury in each pill. 2615. Mercury with Chalk Pills. — These are made yi and 1 grain of Hydrarg. cum Creta, in each pill. 2616. Morphine Pills are made of the Acetate, Muriate, Sulphate, and Valerianate of Morphine r \, yi, Ye, and % grain each, the ' s grain being the size more frequently used. Morphine is also combined with many other salts in the form of pills. 2617. Morphine Compound Pills. (Dr. Hubbard's). — These are made with yi, ]/(,, or X grain of Morphine Sulphate combined with 2 grains of Extract of ilyoscyamus and 1 grain of Camphor, in each pill. 2618. Neuralgia Pills (Brown- Sequard). — Extract Belladonna yi grain, Extract Stramonium -| grain, Ex- tract Cannabis Indica % grain, Extract Aconite J/j grain, Extract Opium yi grain, Extract Conium 1 grain, Extract Ilyoscyamus 73 grain, in each pill. With Extract Ignatia add y 2 grain Extract Ignatia in each pill. 2619. Neuralgia Pills (Dr. Gross). — Sulphate of Quinine 2 grains, Sulphate of Morphine t,\ grain, Powdered Ex- tract Aconite j4 grain, Strychnine ■£$ grain, Arsenious Acid -^ grain, in each pill. Without Morphine, omit the Mor- phine from above formula. 2620. Nux Vomica Extract Pills. — These are made y± and l / z grain of the extract in each pill. 2621. Opium Pills. — Opium is made up into pills of 1 grain each, with Soap as an excipient. 2622. Opium Extract Pills. — Aqueous Extract of Opium is made into y, %, and 1 grain pills. 2623. Opium and Acetate of Lead Pills. — These pills are made with 1 grain each Opium and Acetate of Lead in each pill, also with ]A grain Opium, lyi grain Acetate of Lead, or with Acetate of Lead 6 parts, Opium 1 part, Confection of Roses 1 part, to make a 5 grain pill, the latter being the Br. P. formula. 2624. Ox Gall Pills.— Purified Ox Gall 2 grains, Ginger 1 grain 2625. Phosphate Iron, Quinine, and Strychnine Pills. — Phosphate of Iron 2 grains, Quinine I grain, Strych- nine g 1 ^ grain. 2626. Phosphorus Pills.— The U. S. P. directs Phosphorous Pills to be made by dissolving 1 grain of Phospho- rus in a test tube with 50 grains of puri- fied Chloroform, then mix Althcea 80 grains with Acacia 20 grains in a mor- tar, add the dissolved Phosphorus, mix, then add Glycerin 40 grains, Water 20 grains, to make a mass which is to be divided into 100 pills. These are then to be well coated over with a solution of PILUL.-E — PILLS. 691 Tolu in stronger Ether. Each pill con- tains y^j grain Phosphorus. The Br. P. directs 3 grains of Phos- phorus and 120 grains of Balsam of Tolu to be put into a small mortar about half full of hot water, and when the Phosphorus has melted and the Bal- sam become sufficiently soft they are to be well rubbed together until no parti- cles of Phosphorus are visible, the temperature of the water being main- tained to about 6o c C, 140° F. Yellow Wax 57 grains is then added and mixed with the mass under water, and the whole then allowed to cool and be kept under water. When dispensed, 2 grains of this pro- duct is to be rubbed with one grain of Soap, a few drops of Alcohol being used if necessary to soften the whole. Three grains of the mass represents ^ grain Phosphorus. Washed Tolu is also used as a means of dividing Phosphorus, and an excipi- ent is made with Phosphorus 24 grains, White Wax 60 grains, Venice Turpen- tine 156 grains, which contains ten per cent, of Phosphorus and is very con- venient for making pills. Phosphorus Pills are made j^- G , -fa, **&• 'sV> ~ia grain each of Phosphorus, with Soap, Wax, or other excipient, and should be well coated with a varnish of Tolu or Shellac. 2627. Phosphorus Compound Pills. — Phosphorus , ,* grain, Extract Nux Vomica % grain. These are also made Phosphorus ,.\, grain, Extract Xux Vomica % grain, or Phosphorus -'„ ;f water, heating and dissolving the Oxide to it uration in the liquid, then filtering and concentrating by evaporation and crystallizing. Uses. — This salt is used in solution as an external applica- tion, and for making hair restoratives is preferable to the Ace- tate, as it has a less disagreeable odor. 698 PLUMBUM — LEAD. 2700. Plumbi Oxidum. Oxide of Lead, Litharge. PbO. This is Oxide of Lead which has been rendered semi-crystal- line by incomplete fusion, and is hence called Semi-vitrous Oxide of Lead. It may be prepared in a small way by heating Nitrate of Lead in a platinum crucible until all its acid has been driven off; but, commercially, it is a by-product of extracting silver from lead ore. Uses. — Oxide of Lead is a working basis for many of the lead salts, and is used in making plasters and solutions for external use. Other Salts of Lead. Besides the official Salts of Lead which have been described, several others are occasionally used in pharmacy. 2701. Arseniate of Lead — Pb 3 (As0 4 ) 2 — Made by gradually adding a solution of Acetate of Lead to a solution of Arseniate of Sodium, collecting, washing, and drying the precipitate. As an application to cancers and malignant ulcers. 2702. Bromide of Lead — PbBr 2 . — By adding a solution of Acetate of Lead to a solution of Bromide of Potassium, collecting and washing the precipitate. Uses similar to Iodide of Lead. 2703. Chloride of Lead — PbCl 3 . — By adding gradually to a solution of Acetate of Lead in water Hydrochloric Acid as long as a precipitate is formed, then collecting and drying, or by adding a solution of common salt to the solution of Acetate of Lead. 2704. Chromate of Lead — PbCr0 4 . — By adding a solution of Acetate of Lead gradually to a solution of Bichromate of Potassium and collecting the precipitate. This is a pigment known as Chrome Yellow, Lemon Yellow, Leipsic or Paris Yellow. 2705. Bichromate of Lead, which is known as Chrome Orange or Chrome Red. is made by adding Potassa to the Solution of Bichromate of Potassium before adding the Solution of Acetate of Lead. POTASSIUM OR KALIUM. 699 2706. Cyanide of Lead — PbCy g . — By adding Hydrocyanic Acid to a Solution of Acetate of Lead as long as a precipitate is formed, and collect- ing the same. 2707. Oxides of Lead. — Besides the official Oxide of Lead (Litharge), Binoxide of Lead, Pb0 2 , is made by treating Red Lead wiih Nitric Acid and collecting the undissolved powder, and Red Oxide of Lead ox Red Lead, Pb 3 4 , is made by heating Massicot or unfused Oxide of Lead to a dull red heat in contact with the air until it is converted into a bright red powder. This is also called Minium. 2708. Saccharate of Lead.— By adding a Solution of Saccharic Acid to a Solution of Acetate of Lead as long as a precipitate is formed and collect- ing the same. 2709. Sulphate of Lead — PbS0 4 . — By dissolving Nitrate of Lead in Water, adding Sulphuric Acid as long as a precipitate is formed, then collect- ing the precipitate. 2710. Tannate of Lead. — By precipitating a Solution of Acetate of Lead with a Solution of Tannin and collecting the precipitate. Some other important salts of lead are known, but they are made in the same general manner as the foregoing. POTASSIUM OR KALIUM. Symbol, K; Atomic weight, 39; Sp. gr., 0.865. Potassium is one of the group of four elementary substances (Potassium, Sodium, Lithium, and Ammonium) which, on account of their marked, positive characteristics, are called the Alkali-metals. It was first isolated and described by Sir H. Davy in 1807, and is now chiefly obtained from its carbonate by heating it to a high degree with charcoal, in a retort, when it distills over and is condensed in Naphtha, cooled by ice. It is so readily oxidized that it must be preserved under naphtha or sunn- other hydrocarbon. In water it burns violently and exposed to air is soon converted into an oxide, and its other properties and characteristics arc similar to the Alkali-metals in general. Potassium is tin- basis of a great variety of salts which are formed by its union with acids and negative elements. They 700 POTASSIUM OR KALIUM. are as a class very soluble and are of great value in the indus- trial arts and in pharmacy and medicine. Potassium derives its name from Potash, the chief source of the Potassium salts. Potash was formerly made by evaporating the lye which is obtained by percolating or lixivating wood ashes, but is now chiefly obtained by decomposing native impure Chloride of Potassium, obtained from mines in Germany. The salts of Potassium are either Alkaline, neutral, or acid according to the proportions in which they are combined. In German phar- macy they are called Kalium salts. The official salts of Potas- sium constitute a large class, and are as follows : 271 1. Potassa. Caustic Potash or Potassa, Hydrate of Potassium. KHO. This is prepared by evaporating Solution of Potassa rapidly in a clean iron vessel until an oily fluid remains which will solidify on cooling. It is then poured into cylindrical molds to form " sticks," which, while still warm, are put into dry bot- tles and tightly sealed. It is sometimes made in the form of powder by stirring while cooling. Uses. — This is used chiefly as a caustic for morbid growths, excrescences, warts, etc., and in pharmacy may be used for pre- paring Liquor Potassa (which see) and many salts and prepar- ations of Potassium. 2712. Potassa cum Calce. Potassa with Lime. Potassa, 50 parts or 1 ounce. Lime, 50 parts or 1 ounce. Rub them together in a mortar so as to form a powder and keep in a well-stopped bottle. Uses. — This is used as a caustic, the same as Potassa, but is milder and slower in its action. Being in powder it is some- times more convenient. POTASSIUM OR KALIUM. 701 2713. Potassa Sulphurata. SidpJiuratcd Potassa. Sublimed Sulphur, 1 part or 1 ounce. Carbonate of Potassium, ... 2 parts or 2 ounces. Rub the Carbonate of Potassium, previously dried, with the Sulphur, and heat the mixture gradually in a covered crucible until it ceases to swell and is completely melted. Then pour the liquid on a marble slab and when solidified and cold put into well stopped bottles. This is also known as Liver of Sulphur, and possesses a very disagreeable odor like rotten eggs. Uses. — It is sometimes given internally as an alterative and used externally in solution for skin diseases or parasites. It is used by barbers for removing Nitrate of Silver stains. 2714. Potassii Acetas. Acetate of Potassium. This may be made most conveniently by adding to pure Acetic Acid crystals of Bicarbonate of Potassium as long as effervescence ensues, then adding a very small quantity of acid and cautiously evaporating to dryness in a porcelain dish by means of a sand-bath. Uses. — This is given as a diuretic, especially in derange- ments of the kidneys and bladder, and in rheumatic affections, in doses 10 to 60 grains. 2715. Potassii Bicarbonas. Bicarbonate of Potassium. KHCO3. This salt may be made by passing a current of Carbonic- Acid Gas through a strong solution of Carbonate of Potassium 702 POTASSIUM OR KALIUM. until it is entirely saturated, then filtering the liquid and evap- orating at a temperature below y\° C. (160 F.) that it may not be decomposed, and crystallizing when sufficiently concen- trated. Commercially, crude Bicarbonate of Potassium, which is called Salceratus, is prepared by suspending a solution of Car- bonate of Potassium contained in an open vessel in the fer- menting tuns of a brewery, thus utilizing the Carbonic Acid gas produced. When the solution is saturated it is evaporated to dryness. Uses. — Bicarbonate of Potassium in crystals is largely used in Pharmacy as a source of other Potassium Salts. It is less irritating than the carbonate, and is therefore administered in- ternally when an alkaline Salt of Potassium is desired as an antacid, etc. The dose is from 10 to 30 grains. 2716. Potassium Bichromas. BicJir ornate of Potassium. This is obtained from Chrome Iron Ore by first roasting the ore, then powdering, mixing with Carbonate of Potassium and chalk, and heating the mixture to a high temperature in the air. Ferric Oxide and Chromic Acid are produced, the latter combining with the Carbonate of Potassium and forming neu- tral Chromate of Potassium with evolution of Carbonic Dioxide. The Solution of Neutral Chromate of Potassium, which is obtained by lixivation with Water, is then treated with Sul- phuric or Nitric Acid, and the salt crystallized from the solution. Uses. — This salt, which is also known as Red Chromate of Potassium, is used in pharmacy for making several preparations and as a test-solution. The dose internally is ^ to 4- grain in solution. It is also extensively used in dyeing. POTASSIUM OR KALIUM. 703 2717. Potassii Bitartras. U. S. Potassii Tartras Acida, Br. — Bitartrate of Potassium, U. S. Acid Tartrate of Potassium, Br. — Cream of Tartar. KHC 4 H 4 O fi . This is an acid salt of Potassium prepared from Crude Tar- tar or Argots, which is deposited in wine casks during the fer- mentation of grape juice. Uses. — Cream of Tartar is extensively used as the acid basis of Baking Powder and for other culinary purposes. In medicine it is considerably employed as a mild acid and laxa- tive in doses of ]/> to 4 drachms. 2718. Tartaric Acid — H a C 4 H 4 G . — This is the acid of Cream of Tar- tar, prepared by dissolving 45 ounces av. of Cream of Tartar in 2^ gallons of boiling Water, adding \z l / 2 ounces av. of prepared chalk, and when effer- vescence has ceased 13^ ounces av. of Chloride of Calcium dissolved in 2^ pints of Water. When the Tartrate of Calcium thus found has subsided pour off the liquid and wash the precipitate with Water until tasteless. Then mix 13 fl. ounces of Sulphuric Acid with 60 ounces of Water, pour upon the precipitate, mix thoroughly and boil for half an hour, with repeated stirring, and filter through calico. Evaporate the filtrate at a low temperature until it acquires the sp. gr. of 1. 2i. Allow to cool, separate and reject the crystals of Sulphate of Calcium which form, then evaporate the remaining liquor until a film forms on the surface, and allow it to cool and crystallize. Finally, purify the crys- tals obtained by dissolving, tillering, and recrystallizing. This acid is used in making the Tartrate salts and for other purposes. 2719. Potassii Bromidum. Bromide of Potassium. KBr. The Br. Official process is to add 2 ounces av. of Bromine in sive portions to 1 pint 1 Imperial 1 of Solution of Potash and evaporate to dryness, then mix the powder with wood charcoal in fine powder 1 ounce av., throw, in small quantities at a time, into a red-hol Crucible and when all is fused pour 704 POTASSIUM OR KALIUM. out, and when cooled dissolve in 15 fl. ounces of boiling Dis- tilled Water, filter, evaporate and crystallize. Another process is to decompose a solution of Bromide of Iron with Carbonate of Potassium, Carbonate of Iron being precipitated and the solution, which contains Bromide of'Po- tassium, filtered, concentrated and crystallized. Uses. — Bromide of Potassium is one of the most valuable salts used in medicine. It is employed as a nervine and seda- tive in doses of 20 to 60 grains. 2720. Potassii Carbonas. Carbonate of Potassium — Sal Tartar. (K 2 C0 3J2 . 3 H 2 0. This salt is obtained from commercial PcarlasJi (impure Car- bonate of Potash) by dissolving it in an equal weight of cold Water, " allowing to stand a day or two, filtering the solution and evaporating the filtrate by gentle heat until it thickens, then removing it from the fire and stirring it constantly with an iron spatula until it is in the form of a granular salt, which is known familiarly as " Salts of Tartar." Uses. — This is considerably used as a basis of other Potas- sium Salts and internally as an antacid, and externally in some ointments and lotions. The dose is 5 to 15 grains largely dil- uted. One ounce in 1 gallon of Water makes the Shampoo Liquid used by barbers. 2721. Potassii Chloras. Chlorate of Potassium. The Br. P. directs this to be made by mixing 20 ounces of Carbonate of Potassium with 53 ounces of slacked Lime, trit- urating with a few ounces of Water to make the mixture slightly moist, and putting in a carboy ; then generating Chlo- rine Gas from 80 ounces of Black Oxide of Manganese and 24. pints (Imperial) of Hydrochloric Acid with 6 pints (Imperial) POTASSIUM OR KALIUM. 705 of Water, heated in a retort, on a sand-bath, and conducting the gas thus generated into the carboy containing the mixture of Carbonate of Potassium and Lime until all has passed over. The contents of the carboy are then removed and boiled for 20 minutes with 7 pints (Imperial) of Water, then filtered and the solution evaporated and crystallized. The product is puri- fied by recrystallization. Uses. — -Chlorate of Potassium is extensively used as a source of Oxygen and in pyrotechnics. In medicine, it is used for sore throat, scarlet fever, etc., in doses of 2 to 20 grains. It is quite popular in the form of lozenges and tablets. 2722. Potassii Citras. Citrate of Potassium. K 3 C c H g 7 .H 2 0. This salt is conveniently made by adding Bicarbonate of Potassium to a strong Solution of Citric Acid until it no longer effervesces, then filtering the solution and evaporating to dryness. The Br. P. directs 8 ounces or a sufficiency of Carbonate of Potassium, 6 ounces or a sufficiency of Citric Acid, and 40 fl. ounces of Water. The Acid is to be dissolved in the Water and enough Carbonate of Potassium added to make the solu- tion neutral, then filtered and evaporated to dryness. Uses.— This salt is considerably used in elixirs and other preparations and in medicine as a diaphoretic and refrigerant, to 20 grains. 2723. Potassii Cyanidum. Cyanide of Potassium. KCN. This may be prepared according to the Br. P. process by healing Ferrocyanide of Potassium at a red heat until gas ceases to be evolved, allowing the sediment to subside in the still molten mass, and pouring off the clear fluid. This is 706 POTASSIUM OR KALIUM. called fused Cyanide of Potassium. If desired to be purified, it may be dissolved in spirit, the solution filtered and concen- trated by evaporation, and then crystallized. Uses. — In pharmacy this is used in making several prepara- tions and in medicine it is employed as a sedative the same as Hydrocyanic Acid, in doses of \% of a grain or less. 2724. Potassii et Sodii Tartras. U. S. Tartrate of Pot as shun and Sodium — RocJicllc Salts. U. S. Soda- Tartarata — Tartratcd Soda. Br. KNaC 4 H 4 6 4H 2 0. This is made by dissolving 12 ounces av. of Carbonate of Sodium in 5 pints of boiling water, adding 16 ounces av. of Bitartrate of Potassium (Cream of Tartar) to the solution, boiling for a few moments, and then testing to see if the solu- tion is neutral, and adding a little of either of the salts to make it so if it is not. It is then evaporated until a pellicle begins to form, and set aside to crystallize. Uses. — Rochelle Salt is usually powdered for convenient use, and is employed in pharmacy for making Seidlitz Powders, and in medicine is much used as a laxative and cathartic. The dose is from 2725. Potassii Ferrocyanidum. Ferrocyanide of Potassium — Yellow Prussiate of Potash. K 4 Fe(CN) c . 3 H 3 0. This is obtained by heating refuse animal substances, such as horns, hoofs, skins, etc., with Crude Potash in an iron kettle, then lixivatingor percolating the mass with hot water, treating with freshly precipitated Carbonate of Iron, filtering the solu- tion, concentrating and crystallizing. Uses. — This salt is considerably used for dyeing, and as a test for ferric salts, with which it forms a blue color (Ferro- cyanide of Iron). POTASSIUM OR KALIUM. 707 2726. Potassii Hypophosphis. Hypophosphite of Potassium. KH 2 P0 3 . This salt is prepared by boiling a Solution of Potassa and Phosphorus together, then treating with Carbonic Acid gas to neutralize the excess of Potassa,* evaporating to dryness, dissolving out the Hypophosphite of Potassium with Alcohol, and evaporating to a granular powder. It is also made by double decomposition between Hypophosphite of Calcium and Carbonate of Potassium in solution. Uses. — This salt is combined with other Hypophosphites in solutions and syrups. It is very deliquescent. 2727. Potassii Iodidum. Iodide of Potassium. KI. The U. S. P. gives no formula for the preparation of this salt, but the Br. P. directs : Solution of Potash, Br., . . 1 gallon, Imperial. Iodine, a sufficiency, about . .21 ounces av. Wood Charcoal, in fine powder, . 3 ounces av. Boiling Distilled Water, a sufficiency. Put the Solution of Potash into a glass or porcelain vessel and add Iodine in small quantities at a time, with constant agitation, until the solution acquires a permanent brown tint. Evaporate the whole to dryness in a porcelain dish, pulverize the residue and mix it intimately with the Charcoal, throw the mixture, a small quantity at a time, into a red hot crucible and when all has been brought to a state of fusion pour out the contents. When cooled dissolve it in 2 pints (Imperial) of Boiling Distilled Water, filter the liquid through paper, add a little Boiling Distilled Water through the filter, evaporate the liquid till a film forms on the surface, and set aside to crys- tallize, drain and dry the crystals in a warm place. In a commercial way other methods are employed which are more economical. 708 POTASSIUM OR KALIUM. Uses. — Iodide of Potassium is one of the most valuable medicinal salts. It is employed as the source of other Iodides by double decomposition, and in medicine as an alterative and absorbent in scrofula, syphilis, rheumatism, dropsy, etc., and externally in lotions, ointments, and other forms. The dose of this salt is from 2 to 20 grains, or much more in solution. 2728. Potassii Nitras. Nitrate of Potassium — Saltpetre — Sal Nitre — ■ Nitre. KNO3. This salt is obtained in some parts of the world as a natural product, but is chiefly made by the process of Nitrification. Earth, wood ashes, animal and vegetable refuse, sewage, etc., are mixed together in what are called nitre beds, and by the action of the peculiar ferment which causes nitrification nitre is produced. It is now a well-established fact that nitre is the product of living organisms acting upon appropriate materials. The mixed soils, etc., of the nitre beds, after standing for a long time, are lixivated with water, and the crude Nitre which is obtained by evaporating the liquid, purified and crystallized, in which form it appears in the market. Uses. — In the arts Nitre is extensively employed as an in- gredient of gunpowder and pyrotechnics. In medicine it is used as a diuretic and diaphretic in doses of 5 to 20 grains, and also used externally in solution. Sal Prunelle is fused Nitrate of Potassium cast in the form of balls about the size of small marbles. 2729. Potassii Permanganas. Permanganate of Potassium. K 2 Mn 2 8 . The U. S. P. gives no process for making this salt, but the Br. P. directs : Caustic Potash, 5 ounces av. Black Oxide of Manganese, ... 4 ounces av. Chlorate of Potassium, 3^ ounces av. Distilled Water, 43 fl. ounces. Carbonic Acid, a sufficiency. POTASSIUM OR KALIUM. 709 Reduce the Chlorate of Potassium to a fine powder and mix it with the Oxide of Manganese ; put the mixture in a porce- lain basin and add to it the Caustic Potash previously dissolved in 4 fl. ounces of Water, evaporate to dryness on a sand-bath, stirring well to prevent spurting. Powder the product and place the powder in a covered crucible, exposing it to a dull red heat for an hour or until it has assumed a semi-fluid condi- tion. Let cool, powder it, and boil with 30 fl. ounces of Water, let the insoluble matter decant, pour off the liquid, boil the sediment again with 10 fl. ounces of Water, pour off the liquid and add to that previously reserved, saturate with Carbonic Acid gas and evaporate until a pellicle forms on the surface, then set aside to cool and crystallize ; drain the crystalline mass, boil it in 6 ounces of Water, strain through a little as- bestos in a funnel, again crystallize, drain the crystals and dry them under a bell jar over a vessel containing Sulphuric Acid. Uses. — This salt is used as an antiseptic, disinfectant, and oxidizing agent. It is given internally in small doses in solution and applied externally to putrescent or gangrenous wounds, sores, ulcers, etc. 2730. Potassii Sulphas. Sulphate of Potassium. K 2 S0 4 . Sulphate of Potassium is produced as a by-product of the manufacture of several other more important salts. It may be made by decomposing Nitrate of Potassium with Sulphuric Acid. Uses. — In pharmacy this salt has been mainly used in mak- ing Powder of Ipecac and Opium, in which it acts as a dilutent. 2731. Potassii Sulphis. Sulphite of Potassium — Neutral Potassium Sulphite. K,S() :; .jII 2 0. This salt, which is official in the U. S. P., is made by passing a current of Sulphurous Acid gas through a concentrated Solution of Carbon, it'- of Potassium until the Carbonic Acid 710 POTASSIUM OR KALIUM. gas is expelled and the liquid is strongly acid, then adding an equal weight of Carbonate of Potassium, evaporating and crystallizing, making Neutral Potassium Sulphite. Uses. — This salt is given in doses of 10 to 60 grains as an anti-ferment in bowel troubles, etc., and is sometimes used to prevent fermentation in juices, etc. 2732. Potassii Tartras. Tartrate of Potassium — Neutral Tartrate of Potassium. (K 2 C 4 H 4 6 ) 2 .H 2 0. The U. S. P. gives no formula, but the Br. P. directs : Acid Tartrate of Potassium (Cream Tartar), . . .20 ounces or a sufficiency. Carbonate of Potassium, . 9 ounces or a sufficiency. Boiling Distilled Water, . 50 ounces. Dissolve the Carbonate of Potassium in the Water, add the Cream Tartar a little at a time, and if, after a few minutes' boiling, the liquid is not neutral to test-paper, make it so by the careful addition of more of the Carbonate or Cream Tar- tar ; then filter, evaporate till a pellicle forms and set aside to crystallize. This is known as Neutral Tartrate, and Cream of Tartar is known as Acid Tartrate of Potassium. Uses. — This is used as a laxative in small doses and as a purgative in doses of ^ to 1 ounce. It is used in making Fehling's Solution. Other Potassium Salts. The foregoing official Salts of Potassium are all that are used to any extent in Pharmacy and Medicine, but a number of others are prepared and sometimes called for, the more im- portant being as follows: 2 733- Antimoniates of Potassium. — The Acids of Antimony combine with Potassium the same as other Acids forming normal or neutral and Acid Salts. Antimoniate of Potassium — KSbO s . — Is the normal Salt produced by heating 1 part of Metallic Antimony with 4 parts of Nitrate of Potassium in POTASSIUM OR KALIUM. 711 a crucible, washing the powdered mass with Water, boiling it with Water for an hour or two, which converts a portion of it into a soluble salt, obtained by filtering the solution and evaporating to dryness. Acid Antimoniate of Potassium — K 2 Sb 4 1 1 . — May be made by passing a current of Carbonic Acid gas through the normal Salt. Acid Metantimoniate of Potassium is also prepared and used as a test for Sodium. 2734. Arseniate of Potassium — KH 3 As0 4 . — Heat Arsenious Acid (Anhydride) and Nitrate of Potassium, each in powder, 1 part in a glass flask to dull redness until the mixture fuses and red vapors cease to be evolved. Dissolve the residue when cold in 50 parts of boiling Distilled Water, filter, concentrate the solution by evaporation and crystallize. Dose T 1 ^ to l /% grain in solution. 2735. Bisulphate of Potassium — KHS0 4 . — This is the residue left in the retort after preparing Nitric Acid from Nitrate of Potassium and Sul- phuric Acid. 2736. Bisulphite of Potassium — KHS0 3 .— By passing an excess of Sul- phurous Acid Gas into a concentrated solution of Carbonate of Potassium. 2737. Borate of Potassium— K 4 B 4 O s . — By heating equal parts of dry Carbonate of Potassium and Boric Acid in powder in a covered crucible, dis- solving the sublimed mass in boiling Water, filtering the solution, concen- trating and crystallizing. The dose is 1 to 6 grains, for dissolving cal- culi, etc. 2738. Borortartrate of Potassium. — By heating 4 parts of Cream Tartar with i part Boric Acid in 10 parts or sufficient Water to dissolve them, then evaporating 10 dryness. This is also called Soluble Cream of Tartar. It is very soluble and deliquescent. Used for gout and lithic calculi in doses of 15 to 30 grains, and as a laxative in doses of 2 or 3 drachms. 2739. Chloride of Potassium— KC1. — This is obtained as a by-product in the manufacture of Chlorate of Potassium and other Salts, or may be made by neutralizing a solution of Carbonate of Potassium with dilute Hy- drochloric Acid, evaporating and crystallizing. Dose 10 to 30 grains. 2740. Chromate of Potassium— K 2 Cr0 4 . — By adding Carbonate of Potassium to a hot solution of Bichromate of Potassium until effervescense ceases, concentrating and crystallizing. In a large way it is made direct from Chronic 1 >re, and is extensively used in dyeing. 2741. Cyanate of Potassium — KCNO. — This may be made by mixing mide of Potassium and Litharge and heating, then dissolving out the Cyanate bom the fused mass by Alcohol, and crystallizing. 2742. Ferricyanide of Potassium — K 6 Fe 8 Cy, ... — By passing Chlorine Gas into a cold solution of Ferrocyanide of Potassium until it ceases to give a blue precipitate with Chloride of Iron. It is used as a test. 2743. Iodate of Potassium— K K )., — This is made during the manu- facture ol Iodide of Potassium, and may be obtained by dissolving out the 712 POTASSIUM OR KALIUM. Iodide of Potassium before heating the mixture in a crucible, with Alcohol, and dissolving the residue which is the Iodate in hot Water and crystallizing. 2744. Iodohydrargyrate of Potassium.— This is made by dissolving 2 parts of Iodide of Potassium in a small quantity of hot Water and adding to the solution 3 parts of Iodide of Mercury, upon cooling the salt crystal- lizes. It is used as a test. 2745. Nitrite of Potassium — KN0 2 . — By heating Nitrate of Potassium to redness, dissolving the fused mass in a little Water, adding twice the vol- ume of the solution of Alcohol and after a few hours decanting the upper stratum, separating the crystals from the lower stratum and evaporating to dryness. 2746. Oxalates of Potassium. — With Oxalic Acid Potassium forms sev- eral Salts, as follows : Oxalate of Potassium, K 2 C 2 4 , by neutralizing a solution of Oxalaic Acid with Carbonate of Potassium, evaporating and crystallizing. Binoxalate of Potassium, KHC 2 4 , also called Salts of Sorrel, or Salts of Lemon. By saturating a solution of Oxalic Acid 1 part with Carbonate of Potassium and adding to the mixture 1 part of Oxalic Acid, evaporating and crystallizing. (}uadr oxalate of Potassium. By neutralizing 1 part of Oxalic Acid in solution with Carbonate of Potassium, then adding 3 parts of Oxalic Acid, concentrating and crystallizing. The two last are used to remove iron rust, ink stains, etc., and are gener- ally sold under the name Salts of Lemon ; a simple mixture of powdered Oxalic Acid 4 parts and powdered Carbonate of Potassium 1 part being generally put up for this purpose. 2747. Perchlorate of Potassium — KC10 4 . — By heating Chlorate of Po- tassium until it melts, and keeping at this temperature until gas ceases to be evolved, then dissolving in Water and crystallizing. 2748. Salicylate of Potassium— (KC 7 H 5 3 ) 2 .H 2 0.— This Salt may be made by dissolving 7 parts of Bicarbonate of Potassium in Water, and grad- ually adding 10 parts of Salicylic Acid and evaporating to dryness. 2749. Silicate of Potassium — K„Si0 3 . — By fusing 10 parts of Carbonate of Potassium with 15 parts of fine sand and 1 part of Charcoal a salt is obtained similar to Silicate of Sodium, which is used for making Water Glass. 2750. Sulphide of Potassium — K 2 S. — By passing a current of Sulphu- retted Hydrogen into a solution of Potassa as long as it is absorbed, then ad- ding an equal quantity of solution of Potassa and evaporating. See also (2713). 2751. Sulphocarbonate of Potassium — K,CS :i . — By mixing a solution of Sulphide of Potassium with Bisulphide of Carbon and evaporating without heat. 2752. Sulphocyanate of Potassium — KSCN. — By melting together 17 parts of Carbonate of Potassium, 32 parts of Sulphur and 46 parts Anhydrous PROPYL OR TRITYL. PULVERES — POWDERS. 713 Ferrocyanide of Potassium and heating to redness, exhausting with Water, evaporating the solution to dryness, powdering and exhausting with Alcohol and crystallizing. This is chiefly used as a test for Ferric Oxide. Other Salts of Potassium are known, but the foregoing are all that are liable to be called for. PROPYL OR TRITYL. The gaseous radical of which Propylic Alcohol, C 3 H 7 HO, is the hydrate is known as Propyl or Trityl. Propylic Alcohol is a fusel oil obtained from the fermented residuum of ex- pressed grapes after the marc-brand)' has passed over. It is also called fusel oil of marc-brandy. It combines with Ammonia, forming Propylamine, with Phenol, forming Phenol-Propyl-Alcohols, etc. PULVERES — POWDERS. Aside from the general meaning of the word Powder or Powders as describing any finely comminuted substance, the term is applied in Pharmacy to a class of Compound Powders which have been adopted as convenient or efficient prepara- tions to be dispensed in this form. Other Powders, as Tooth Powders, Face Powders, etc., are found under their proper headings, only these which are intended to be used as medi- cine being included here. The following are those official in the leading Pharmaco- poeias : 2753. Pulvis Aerophorus. G. P. Effervescing Powder. Bicarbonate of Sodium 10 parts. ii Acid 9 parts. Sugar 19 parts. Dry them separately in tine powder at a gentle heat and then mix them in- timately. When mixed with water they effervesce with liberation of carbonic acid gas. 714 PULVERES — POWDERS. 2754. Pulvis Aerophorus Anglicus. Soda Powders. The German formula under the above title is : Bicarbonate of Sodium, put up in a blue paper, . . 2 grammes. Tartaric Acid, put up in a white paper, 1 y z gramme. Under the title Pulveres effervescentes they were official in the 1870 U. S. P. Bicarbonate of Sodium 360 grains and Tartaric Acid 300 grains were each put up separately in 12 powders each. When given, one of each of the powders is dissolved in one ounce of Water and the solution mixed and drank during effervescense. 2755. Pulvis Amygdalae Compositus. Br. Compound Powder of Almonds. Sweet Almonds 8 ounces or 8 parts. Refined Sugar 4 ounces or 4 parts. Gum Acacia 1 ounce or 1 part. Blanch the Almonds, dry them thoroughly and powder them, then mix with the Gum and Sugar. This is used for making mixture of almond. 2756. Pulvis Antimonialis. Antimo7iial Powder — Janus Powder. Oxide of Antimony 1 ounce or 1 part. Precipitated Phosphate of Calcium, .... 2 ounces or 2 parts. Mix them intimately. Dose 3 to 5 grains. 2757. Pulvis Aromaticus. U. S. Aromatic Powder. Cinnamon, No. 60 powder, 7 drachms. Ginger, No. 60 powder, 7 drachms. Cardamom, No. 60 powder, 3 drachms. Nutmeg, No. 60 powder, 3 drachms. Mix them intimately. Under the title Pulvis Cinnamomi Composzttis, Compound Powder of Cinnamon, the Br. P. directs Cinnamon, Cardamom Seeds and Ginger, each in fine powder, 1 ounce. Aromatic Powder is used for making several preparations, and as an ad- dition to other powders. PULVERES — POWDERS. 715 2758. Pulvis Catechu Compositus. Br. Compound Pou'der of Catechu. Catechu, in powder, 4 ounces or 4 parts. Kino, in powder, 2 ounces or 2 parts. Rhatany, in powder, 2 ounces or 2 parts. Cinnamon, in powder 1 ounce or 1 part. Nutmeg, in powder, 1 ounce or 1 part. Mix them thoroughly, pass the powder through a fine sieve and rub it lightly in a mortar. Dose 20 to 40 grains as an astringent for bowel com- plaints, etc. 2759. Pulvis Cretae Compositus. U. S. Compound Chalk Powder. Prepared Chalk 30 parts or 3 ounces. Acacia 20 parts or 2 ounces. Sugar, 50 parts or 5 ounces. Mix them intimately. This powder is used for making chalk mixture and is given in powder for summer complaints and teething, in doses of 10 to 60 grains. The Aromatic Powder of Chalk of the Br. P. is Cinnamon 4 ounces, Nut- meg 3 ounces, Saffron 3 ounces, Cloves 1 ^ ounce, Cardamom Seeds 1 ounce, Refined Sugar 25 ounces, Prepared Chalk 1 1 ounces, all in powder, and in- timately mixed. 2760. Pulvis Cretae Aromaticus cum Opio. Br. Aromatic Powder of Chalk and Opium. Aromatic Powder of Chalk, Br., 39 parts. Opium, in powder, 1 part. Mix them thoroughly, pass the powder through a fine sieve and finally rub it lightly in a mortar. The dose is 10 to 40 grains, for looseness of the bowels. 2761. Pulvis Effervescens Compositus. U. S. Seidlitz Powders Aperient Effervescing Powders. bicarbonate of Sodium 480 grains. Tartrate of Potassium and Sodium, 1440 grains. 716 PULVERES — POWDERS. Mix them intimately together and divide into 12 powders, which are to be put up in blue papers. Tartaric Acid, in fine powder, 420 grains. Divide into 1 2 powders, which are to be put up in white paper. When taken the contents of one of the blue papers is to be dissolved in about \% ounce of water, and the contents of one white paper in about one ounce of water. The solutions are then to be mixed and immediately drank during effervescense. The German Pulvis Aerophorus Laxans is about the same. 2762. Seidlitz Mixture is prepared with 1 part of Bicarbonate of Sodium and 3 parts of Tartrate of Potassium (Rochelle Salt) intimately mixed. Seidlitz Measures made of boxwood may be had, by which a sufficient quantity of the mixture is taken for each powder. 2763. Pulvis Elaterini Compositus. Br. Compound Powder of Elaterin. Elaterin 5 grains or 1 part. Sugar of Milk 195 grains or 39 parts. Rub them together in a mortar until they are reduced to a fine powder and intimately mixed. Dose X to 5 grains. This contains only "zyi per cent, of Elaterin. The U. S. Trituration of Elaterin contains 10 per cent. 2764. Pulvis Glycyrrhizse Compositus. Compound Powder of Glycyrrhiza or Liquorice. The U. S. formula is : Senna, in powder 18 parts or 2}( ounces. Liquorice Root, in powder 16 parts or 2 ounces. Fennel, in powder 8 parts or 1 ounce. Washed Sulphur, 8 parts or 1 ounce. Sugar, in fine powder, 50 parts or 6% ounces. Mix them thoroughly by rubbing together and passing through a sieve. The Br. formula differs but slightly from this in proportion of ingredi- ents and corresponds with the German Pulvis Liqitiritce Compositus, which is Senna, Liquorice, each 2 parts, Fennel, Washed Sulphur, each 1 part, Sugar 6 parts. This is also called Laxative Powder and Brustpulver, and is used both as a laxative and pectoral, in doses of half to a teaspoonful or more in a little water. PULVERES — POWDERS. 717 2765. Pulvis Gummosus. G. P. Compound Powder of Acacia — Gummipulver. Acacia 15 parts or 3 ounces. Liquorice Root 10 parts or 2 ounces. Sugar, 5 parts or 1 ounce. Used in cough mixtures, etc. 2766. Pulvis Ipecacuanhas et Opii. U. S. Pulvis Ipecacuanha; Compositus, Br. — Pulvis Ipecacuanha; Opiatus, G. P. — Dover's Powder — Pcwder of Ipecac and Opium — Compound Powder of Ipecacuanha. The present U. S. formula is : Ipecac, in powder, 10 parts or 1 ounce. Opium, in powder 10 parts or 1 ounce. Sugar of Milk, in powder, 80 parts or 8 ounces. Rub them together to a very fine powder. The German preparation is identical with this. The Br. formula corresponds with the 1870 U. S. formula, using Sulphate of Potassium in fine powder instead of Sugar of Milk. This formula is still preferred, and with good reason, by many practitioners. 2767. Pulvis Jalapae Compositus. Compound Powder of fa/ap. The U. S. formula is : Jalap, in powder 35 parts or 1 ounce. Bitartrate of Potassium, in powder, .... 65 parts or 2 ounces. Rub them together until they are thoroughly mixed. The Br. formula is Jalap, in powder, 5 parts. Acid Tartrate of Potassium (Cream of Tartar) 9 parts, Ginger, in fine powder, 1 part. The dose of this powder is 20 to 60 grains, usually given in syrup. 2768. Pulvis Kino Compositus. Br. ( 'ompound Powder of Kino. Kino, in powder 3^" ounces or 15 parts. Opium, in powder %. ounce or 1 part. Cinnamon, in powder 1 ounce or 4 parts. Mix them intimately. The dose is 5 to 20 grains for looseness of the bowels, etc. 718 PULVERES — POWDERS. 2769. Pulvis Morphinae Compositus. Cotnpojind Powder of Morphine — Tully's Powder. This preparation was introduced by Dr. Tully, and has been quite popular with physicians as a substitute for Dover's Powder. Sulphate of Morphine 1 part or 22 grains. Camphor 20 parts or 1 ounce av. Liquorice Root, in powder 20 parts or 1 ounce av. Precipitated Carbonate of Calcium, ... 20 parts or 1 ounce av. Alcohol, a sufficient quantity. Powder the Camphor by rubbing it with a little Alcohol, then add the Liquorice and Chalk, and rub to a uniform powder. Rub the Morphine first with a small portion of the powder, then gradually add the remainder, rub- bing them intimately together. Another form of Tully's Powder is made with Opium 60 grains, Camphor, Liquorice, and precipitated Chalk, each 180 grains, powdered and thoroughly mixed. 2770. Pulvis Opii Compositus. Br. Compound Powder of Opium. Opium, in powder, \]A ounce or 3 parts. Black Pepper, in powder, 2 ounces or 4 parts. Ginger, in powder, 5 ounces or 10 parts. Caraway Fruit, in powder, 6 ounces or 12 parts. Tragacanth, in powder l / 2 ounce or 1 part. Mix them thoroughly. The dose is 2 to 5 grains for bowel trouble, etc. This powder is used for making confection of Opium, 1 part to 4. 2771. Pulvis Rhei Compositus. Compound Powder of Rhubarb — Gregory 's Powder. The U. S. formula is Rhubarb, in powder 25 parts or i]/ 2 ounces. Magnesia (calcined), 65 parts or 6>£ ounces. Ginger, in powder 10 parts or 1 ounce. Rub them thoroughly together. The Br. formula is Rhubarb 2 ounces. Light Magnesia 6 ounces. Ginger 1 ounce. PULVERES — POWDERS. 719 The German formula for Powder of Magnesia and Rhubarb is : Rhubarb, 15 parts. Oleo-Saccharate of Fennel, 40 parts. Carbonate of Magnesium 60 parts. The dose of this powder is from 20 to 60 grains, as a laxative and antacid stomachic. 2772. Pulvis Salicylicus cum Talco. G. P. Powder of Salicylic Acid and Talc. Salicylic Acid 3 parts. Wheat Starch 10 parts. Talc 87 parts. Mix them thoroughly. This powder is used as a dusting for chapped or inflamed surfaces, or as a Baby Powder. 2773. Pulvis Scammonii Compositus. Br. Compound Powder of Scammony. Scammony Resin, in powder, 4 ounces or 4 parts. Jalap, in powder 8 ounces or 8 parts. Ginger, in powder 1 ounce or 1 part. Mix them thoroughly. This is used as a cathartic in doses of 10 to 20 grains. 2774. Pulvis Tragacanthae Compositus. Compound Powder of Tragacanth. Tragacanth, in powder 1 ounce or 1 part. Gum Acacia, in powder 1 ounce or 1 part. Starch, in powder 1 ounce or 1 part. Refined Sugar, in powder 3 ounces or 3 parts. Rub them well together. Dose, 20 to 60 grains. Unofficial Powders. Tin- foregoing powders include those official in the leading pharmacopoeias, but many others arc used in pharmacy. The (20 PULVERES — POWDERS. following are the more important unofficial powders used in medicine which are not included under other headings : 2 775- Aloes and Canella Powder. Pulvis Aloes et Canella (Htera Pier a). This powder was formerly official under the above title : Socotrine Aloes, in fine powder 4 ounces. Canella, in fine powder 1 ounce. Rub them together until they are thoroughly mixed. This is familiarly known as " Picra," and used as a bitters, physic and vermifuge. Liquid Picra may be prepared by macerating i l / 2 ounce av. of the above powder in diluted alcohol 1 pint, and filtering. 2776. Aloes Powder Compound. Aloes, in fine powder, 3 ounces. Guaiacum Resin, in fine powder 2 ounces. Aromatic Powder 1 ounce. Rub them well together. This is a warm, sudorific, purgative, in doses of 10 to 20 grains. 2777. Aloes and Iron Powder. — Aloes i}& ounce, Myrrh 2 ounces. Sul- phate of Iron 1 ounce, Extract of Gentian dried, 1 ounce, all in fine powder and thoroughly mixed. Dose 10 to 20 grains. 2778. Calomel and Jalap Powder. — Calomel 1 part, Jalap 2 parts, in- timately mixed. The dose is 20 to 30 grains as a purgative, in syrup. This was the popular physic of our grandfathers but has been mostly superseded by other Less heroic preparations. 2779. Composition Powder — (Thompsonian). — Bayberry Bark 1 pound av., Ginger, Cloves, Capsicum, each 1 ounce av. All in fine powder and in- timately mixed. A teaspoonful in a cup of boiling water, to be drank hot, as a diaphoretic, etc. Another formula is : Hemlock Bark 2 pounds, Bayberry Bark 1 pound, Ginger y z pound, Cap- sicum, Cloves, each 1 ounce, all in fine powder and intimately mixed. This powder is not so strong as the preceding, and the Hemlock Bark is con- sidered an addition to its diaphoretic properties. The dose is 1 or 2 teaspoons- ful prepared as above. 2780. Cubebs and Alum Powder. — Cubeb, in fine powder, 4 ounces, Alum, in fine powder, 1 ounce. Mix them. The dose is 2 drachms or less for Gonorrhoea or other vitiated discharges. One part of this powder may be mixed with 4 parts of Syrup and given in this form. PYROXYLINUM. 721 2781. Diapente Powder.— Serpentaria, Gentian, Bayberry, Myrrh, Phos- phate of Lime, each in fine powder equal parts, thoroughly mixed. 2782. Fumigating Powder. — Amber, Mastich, Olibanum, each 3 parts, dry Storax 2 parts, Benzoin and Labdanum, each 1 part, all in coarse powder and well mixed, to be burned on hot coals. 2783. Insect or Fly Powder. — This is the powdered unexpanded flow- ers of Pyrethrum Roseum or Persian Chamomile. It is not poisonous ex- cept to insects which breathe by trachea; on their sides, and are asphyxiated by it. 2784. Worm Powder. — Worm Powders are made in great variety, but are chiefly composed of Santonine combined with some laxative, as Santo- nine 60 grains, Calomel 60 grains, Sugar of Milk 60 grains, rubbed together and divided into 30 powders, one of which may be given to a child of 6 to 10 years old before meals. 2785. PYROXYLINUM. Pyroxylin — Soluble Gun Cotton. This is made by the U. S. P. as follows: Cotton, 1 part or 1 ounce. Nitric Acid, 10 parts or 10 ounces. Sulphuric Acid, 12 parts or 12 ounces av. Alcohol, ... I Stronger Ether, - . . . each a sufficient quantity. Water, . . . j Mix the Acids gradually in a glass or porcelain vessel, and when the temperature of the mixture has fallen to 30 C. (90 F.) add the Cotton. By means of a glass rod imbue it thoroughly with the Acids and allow it to macerate for 10 hours or until a sample of the Cotton taken out, washed thor- oughly with Water, and subsequently with Alcohol and pressed, is found to be soluble when shaken in a test-tube with a mixture of 1 volume of Alcohol and 3 volumes of stronger Ether. Then remove the Cotton from the Acids and wash thoroughly with successive portions of cold Water and after- wards with boiling Water, then drain and dry by heat of a water-bath. 722 RESINS — RESINS. Soluble Gun Cotton, as thus prepared, is chemically Di- nitro Ccllulin, and is soluble in a mixture of Alcohol and Ether, making the Collodion of pharmacy. It combines with Camphor, making Celluloid, which, by pressure, is made into a hard, flexible substance used for making toilet and other fancy articles, imitating ivory and other substances by adding color- ing ingredients. It is extensively manufactured from wood- paper pulp for this purpose. By varying the strength of the Nitric Acid used three kinds of Gun Cotton may be prepared varying in soluble properties — Mononitro-Cellulin being but slightly explosive and insoluble, Dinitro-Cellulin (the official pyroxylin) being more explosive and soluble in a mixture of Alcohol and Ether, and Trinitro- Cellulin, which is made with the strongest acids, being very explosive but insoluble. This is the Gun Cotton chiefly used for mining operations. RESINS — RESINS. Including Gujus. Gum-Resins, and Resinous Substances. Resins, as understood in pharmacy, are substances obtained from vegetable matters, insoluble in water but soluble in oils, alcohol or ether, and, obtained as natural exudates, or as resi- dues by distillation from oleo-resins or turpentines, or by pre- cipitation from alcoholic fluid extracts of drugs in which they naturally exist as active principles. The Gums, Gum-Resins, and Resinoids are also included in this section as they have similar origin and characteristics. 2786. Resina. Resin — Colophony. The residue left after distilling off the volatile oil from the crude turpentine obtained from various species of Pinus. It is often improperly called Rosin. It is a hard, brittle, transparent substance, from a very pale to a dark amber color, and consists of Abietic Anhydride, which, when treated with dilute alcohol, is converted into Abietic Acid. Uses. — Resin is extensively used in the industrial arts for various purposes and in pharmacy is employed to impart adhesiveness to ointments, cerates, and plasters. RESIN.E — RESINS. 723 Resin Oil is an oil obtained by the dry distillation of Resin. It is used for lubricating, etc., being first made into a soap with slacked lime. It is an ingredient of axle-grease. 2787. Resina Copaibae. Resin of Copaiba. The residue left after distilling off the volatile oil from Copaiba. It is a yellowish, brittle resin, of a weak odor and taste of Copaiba, and an acid reaction. It is used to combine with Copaiba and Oil of Cubebs, making "Extract of Cubebs and Copaiba," a paste or soft mass, used for Gonor- rhoea. 2788. Resina Damar. Demur Resin. A Resin obtained from various species of Damar a, found in Southern India. It is a clear or light amber-colored Resin, used for making Demar Varnish by dissolving in Oil of Turpentine, and as a dusting for various purposes. It is official in the G. P. 2789. Resina Jalapae. Resin of Jul up. Jalap, in No. 60 powder 16 ounces av. Alcohol, ) , cc ■ . y each a sullicient quantity. Water, j Exhaust the Jalap by percolating with Alcohol in the water-bath perco- lator as directed (1069), and evaporate the percolate by distillation to 6 l / 2 fl.ounces, which add to one gallon of water, gradually, and with constant stirring, wash the precipitate with fresh water. Drain, press and dry by gentle heat. This is used as a cathartic, usually in Pills. 2790. Resina Podophylli. Resin of Podophyllum — {Podophyllin?) Podophyllum, in No. 60 Powder 16 ounces. Hydrochloric Acid 1 fl. drachm. Al( <>hol. ) , • r each a sufficient quantity. W .iter, ) ' ' Exhaust the Podophyllum by percolating with Alcohol in the water-bath percolater as directed (1069) and evaporate the percolate by distillation to the consistence of Honey, which is then to be slowly added, with constant Stirring, to 1 pint of Water, previously cooled by ice and mixed with the 724 RESINS — RESINS. Hydrochloric Acid. Wash the precipitate twice with cold water, drain, press and dry in a cool place. This is more commonly called Podophyllin, and is the active principle of Mandrake or May-apple root. Uses, — This is extensively used in the manufacture of Liver and Cathar- tic Pills and given in powders. The dose is y% to i grain. 2791. Resina Scammonii. Resin of Scammony. Scammony, in No. 60 Powder 16 ounces av. AlCOhol, ) , rr- . V each a sufficient quantity. Water, [ M 3 Digest the Scammony with successive portions of boiling Alcohol until ex- hausted. Mix the tinctures thus obtained, and evaporate by distillation to a syrupy consistence. Then add the residue to 2^ pints of water, wash the precipitate with water and dry it with gentle heat. Uses. — Resin of Scammony is used in making pills, powders, etc. The dose is from 3 to 10 grains. The foregoing Resins are official in the leading pharmaco- poeias. The following unofficial Resins are considerably used : 2792. Amber — Succinum. — Also called Electron from its property of generating electricity. A fossil-resin, supposed to have been produced by species of Pinus now extinct. It is used for making ornaments, mouth-pieces of pipes, etc. By dry distillation it yields Acetic Acid and Oil of Amber, which pass over as liquids into the receiver, and Succinic Acid, H 2 C 4 H 4 4 , which sublimes and gathers in the neck of the retort, and which combines with bases forming Succinates. Amber is extensively used for making fine varnishes. 2793. Anime — Gum-Anime, West India Copal. — A pale brownish-yel- low, brittle, transparent Resin, obtained from a species of locust in the West Indies. It emits a very fragrant odor when burned, and is used as a fumiga- tion for asthma and in solution is externally applied. It is used in making pastilles and for varnishes. 2794. Asphaltum. — A black, hard, brittle variety of bitumen found in various parts of the world as a natural exudation from the earth. It is also called Mineral Pitch, Fossil Bitumen, etc. It is not properly included with the Resins but has similar characteristics. Liqtiid Asphaltum. — This is prepared as a Black Japan or gloss varnish by melting Asphaltum l / 2 pound av., adding Balsam Copaiba, heated, 1 pound, and thinning with Oil of Turpentine. Ordinary Black Asphaltum Varnish is made by melting Asphaltum and adding twice its weight of hot Oil of Turpentine. RESIN^E — RESINS. 725 2795. Caoutchouc — India Rubber — Resina Elastica. — This is the con- crete juice of several species of Elastica found in tropical countries. The fresh milky juice is spread over mounds of unbaked clay and exposed to heat by torches, from which its smoky color is derived. Successive layers of the juice are spread on until the mass is sufficiently thick and hard, when the clay is broken. India Rubber is extensively used in the arts, for a great variety of purposes. Its solution in ether or benzol is used as an adhesive and a water-proof covering for fabrics. Vulcanized Rubber or Hard Rubber is made by combining Caoutchouc with from 12 to 15 per cent, of Sulphur, by heating them together. It is used for making a great variety of useful and ornamental articles. 2796. Copal — Gum Copal. — A resinous exudate from various species of locust and other trees found in tropical countries. The variety obtained from East India is known as Gum Anime (2793), that from the West Indies is known as Copal. These resins are extensively used in the manufacture of varnishes. 2797. Dragon's Blood — Sanguis Draconis, Resina Draconis. A rich- red resin obtained from the fruit of Calamus Draco, a species of palm, by beating or shaking the fruit in a bag, which breaks off the resin, which is then separated, melted and run into reed moulds or masses as it appears on the market. Its solution is used for coloring some medicinal substances, varnishes and lacquers. 2798. Guaiac Resin — Gum Guaiac. — This Resin is obtained by various means from Guaiacum Officinale and contains Guaiac ic Acid, C 13 H 16 6 , and several other similar compounds. By dry distillation an Oil is obtained containing Guaiacol, C 7 H 8 2 , Guaiacene, C 8 H 8 0, and other compounds. Uses.— Guaiac Resin is used in making several preparations, and in medi- cine is employed for gout, rheumatism, etc., either in solution or in powder. 2799. Gutta-Percha. — This is a substance resembling India Rubber, ob- tained from Isonandro Gutta, growing only in the Malayan Archipelago. The tree is notched or tapped and the milky juice which exudes exposed to the air for some time when it solidifies, forming the Gutta Percha of com- merce. It is purified and made into sheets which are elastic, pliable and tough, and may be moulded into any desired form. Its solution in Benzol or Bisulphide of Carbon is used for adhesive purposes, and for making water- proof fabrics. 2800. Lac. — A resinous substance, combined with considerable coloring matter, obtained from the branches of several tropical trees and produced by the puncture of an inset, Coccus /area. The crude resinous substance is Stick Lac. Shellac is prepared by melting the resin in long linen bags be- fore a fire and spreading it on bamboo in thin layers. It is obtained in scales. It is used as a varnish and for making sealing wax, etc. Lac Dye is the coloring matter obtained from Lac by washing with water, and Seed Lac is the residue obtained after dissolving out most of the coloring matter from the crude I.ac. 726 RESINS — RESINS — GUMS. 2801. Mastic — Gum Mastic. — A resin obtained from Pistacia Lentis- cus by incising the bark and collecting the exudate. It occurs in tears, is- soluble in Alcohol and in Oil of Turpentine, and is used for making a varnish for pictures and for making cements, and as a dusting for gilding on leather, cloth, etc. for bookbinders' use. 2802. Sandarach — Gum Sandarach. — This is a resinous exudate ob- tained from Thuja articulata and Juniperus communis grown in warm cli- mates. It is used in making spirit varnish for photographic plates, etc., and in the form of powder for pounce bags, etc. Gums. Under this commercial title are included a great number of substances which are pharmaceutically classed under other headings. In pharmacy the substances classed as gums are natural exudates from trees or plants, which are soluble, or partly soluble, in water, and not in Alcohol, Ether, or Oils, Acacia or Gum Arabic being the most perfect type of this kind. Acacia and Tragacanth, which are official, are the only true gums. The remainder, which are thus classed commercially, consisting of balsams, oleo-resins, turpentines, resins, gum- resins, stearoptens (camphor), and inspissated or concrete juices (as aloes and opium), and extracts (as catechu). 2803. Acacia. Gum A?-abic. This is a natural exudate, obtained from various species of Acacia, found in Arabia, Morocco, Turkey, Africa and the East Indies, the product gener- ally bearing the name of the country or locality from which it is obtained — as Gum Arabic from Arabia, Barbary or Morocco Gum from Morocco, Gum Senegal from the settlements on the Senegal River, and East India Gum from Bombay. They are all furnished commercially as Gum Arabic of dif- ferent qualities, the best being known as Extra, Select, White, and the in- ferior qualities as 1st, 2d, 3d, 4th, 5th, Select and Sorts. Acacia consists chiefly of Arabic Acid or Arabin, combined with lime, potassium, or magnesium. Uses. — It dissolves in water forming mucilage, and is used for making Syrup Acacia, and in making troches, pills, powders, etc. In medicine it is used as a demulcent. Gum Senegal is a species of Acacia extensively used in the arts. RESIX.E — RESINS — GUMS. 727 2804. Tragacantha. Tragacanth or Gtim Tragacanth. This is a gummy exudate from several varieties of Astragalus, found in western Asia. It contains about 33 per cent, of Bassorin, an insoluble gum,' and 53 per cent, of a soluble gum peculiar to it. Uses. — Tragacanth absorbs water and forms a gelatinous mass or paste, which is used as a mucilage. It is used in the form of a powder to give ad- hesive properties to lozenges, troches, etc., also to make bandoline and hair fixers. Besides these gums, which are official, a few others are known and some- times used, as Cherry-tree Gum, which is mostly insoluble, Hog Gum from Rhus Metopium, Mesqtiit Gum from Algarobia Glandulosa, etc. The following substances are classed commercially with Gums, but are known in pharmacy by the names they bear : 2805. Aloes. — The inspissated juice of the leaves of several varieties of Aloes found in Africa. Socotrine Aloes only is official in the U. S. The Br. P. recognizes Socotrine and Barbadoes Aloes. See page 135. It is com- monly known as Gum Aloes. 2806. Camphor — Gum Camphor — C 10 H 16 O. — Although Camphor is a stearopten — an oxygenated turpene — possessing none of the properties of gums or gum-resins, and does not properly belong in this department, it is commercially classed with gums, and is familiarly known as " Camphor Gum." It is obtained by subliming the crude Camphor, imported from China and Japan, from Cinnamonum Camphora, in shallow iron vessels, the sublimed Camphor collecting on the covers of the vessels. Uses. — Camphor is one of the most familiar household remedies, " Spirits of Camphor " being used for everything. In pharmacy it is much used in making liniments, ointments, and other external applications and also an ingredient of many preparations given internally. It is a stimulant and may be given in doses of 2 to 10 grains. It is sold extensively to pack with furs to prevent moths, etc. Monobromated Camphor — C, H, 5 BrO. — This is prepared by the reaction of Bromine upon Camphor, and subsequent separation of the crystalline mass, and purification. It is given as a nervous sedative in doses of 2 to 5 grains. 2807. Catechu. — An extract prepared from the wood of Acacia Catechu, containing Catcchu-tannic Acid, Catcchin and Catechol. It is known com- mercially as Gum Catechu, (aim Cutch, Terra Japonica, etc. It is exten- sively used for dyeing and tanning, and in medicine as an astringent and tonic, the dose being from 5 to 20 grains. 2808. Kino — Gum Kino.— The inspissated juice of Pterocarpus Mar- SUpt'um, found in the East Indies, and containing several astringent principles. 728 RESIN. E — RESINS — GUM-RESINS. It is used in pharmacy for making Tincture of Kino, and in medicine is employed as an astringent and tonic, in doses of 5 to 20 grains. 2809. Opium — Gum Opium. — The concrete milky exudation from Pafia- -ver Somniferum. Although classed commercially with the gums it has none of their characteristics. See 2433. Gum-Resins. Gum-Resins, as understood in pharmacy, are natural exu- dates from trees or plants, consisting' of gum, a portion soluble in water, and Resin, soluble in alcohol, therefore possessing the properties of both Gum and Resin. They are all classed commercially and familiarly known as Gums. The following are official in the U. S. and Br. pharma- copoeias, under the titles given : 2810. Ammoniacum. Ammoniac or Gum Ammoniac. A Gum-Resin obtained from Dorema Ammoniacum, containing about 25 per cent, of Gum, 70 per cent, of Resin, and 3 per cent, of volatile oil. It forms an emulsion when rubbed with water, and is somewhat employed as an expectorant and stimulant. It is also given in powders. The dose is 5 to 1 5 grains. 2811. Resorcin. — C G H 6 3 — Ammoniac is exhausted with alcohol, and the alcohol distilled until an extract only remains ; this is carefully fused with three times its weight of caustic potassa; the mass is then dissolved in water and slightly acidulated with sulphuric acid, the solution filtered and agitated with ether. The etherial portion is then separated and distilled or evaporated, leaving impure Resorcin as a residue, which is purified by dis- solving in ether, distilling and crystallizing. Resorcin is used as an antiseptic in fevers, cholera, etc., in doses of 5 to 10 grains. 2812. Asafcetida. Asafetida or Gum Fetida, A Gum-Resin obtained from the root of Ferula Narthax and other species of Ferula, containing about 20 per cent, of Gum and about 70 per cent, of Resin and a volatile oil. A portion is soluble in water, but the valuable portion is soluble in alcohol. It forms an emulsion when rubbed with water. It is em- ployed as an antispasmodic in doses of 3 to 10 grains, and is given in the form of tincture and syrup for worms. Owing to its disagreeable odor it is usually given in the form of pills. RESINjE — RESINS — GUM-RESINS. 729 2813. Cambogia. Gambogia, Gum Gamboge. A Gum-Resin obtained from Garcinia Hanburii, containing about 20 per cent, of Gum and 75 per cent, of Resin, called Gambogic Acid. It is a pow- erful hydrogogue cathartic, and is mostly used in combination with other substances in cathartic pills. The dose is l /> to 3 grains. It is also used as a pigment, making with water a glossy golden color. 2814. Galbanum. Gum Galbanum. A Gum-Resin obtained from Ferula Galbaniflua, containing 20 per cent, of gum, 65 per cent, of resin, and about 8 per cent, of volatile oil. It is a valu- able ingredient of plasters and is used in pills. Its resin, extracted with alco- hol, yields resorcin by the same treatment as is employed with ammoniac, and by dry distillation Umbelliferone, C 9 H 6 3 , which is the principal in gums, giving a blue color when dissolved with water and a little ammonia added. Galbanum is employed internally as an antispasmodic, in doses of 5 to 1 5 grains. 2815. Myrrha. Myrrh — Gum Myrrh. A Gum-Resin obtained from Balsamodendro?i Myrrha, containing about 30 per cent, of gum, 60 per cent of resin, about 3 per cent, of a volatile oil, and a bitter principle. Myrrh is used in making several official preparations and employed in medicine as a stimulant and tonic. The dose is 5 to 20 grains. 2816. Scammonium. Scammony. A dried exudation from the root of Convulvulus Scammonium, containing gum and resin. The best varieties are called Virgin Scammony. It is used for making Resin of Scammony and in medicine as a purgative. Other Gum-Resins. Several other Gum-resins besides the foregoing official ones are used in pharmacy and medicine. The more important are as follows: 2817. Bdellium— 1 htm Bdellium. — A substance resembling Myrrh, obtained from Africa and the East Indies. It is used as a stimulant and orant. 2818. Euphorbium. — A substance containing about 18 per cent, of gum and 38 per cent, of resin, obtained from Euphorbium resinifera found in Morocco. It is used in irritating plasters, especially in veterinary practice, and in catarrh snuffs, etc. 730 RESIN.E — RESINS — GUM-RESINS. 2819. Olibanum — Gum Olibanum or Frankincense. — A Gum-Resin obtained from several species of Boswellia. It resembles Myrrh and is burned as incense. It contains 30 to 36 per cent, of gum and about 56 per cent, of resin, with a little volatile oil and insoluble gum (bassorin). It is used in making plasters and some other preparations. 2820. Opoponax — Gum Opoponax.— A Gum-Resin obtained from the roots of Opoponax Chironium, and containing gum, volatile oil, and resin. It is sometimes used as a stimulant and in plasters. 2821. Sagepenum — Gum Sagepenum. — A Gum-Resin obtained from some species of Ferula, somewhat resembling Asafetida and Galbanum. Factitious Gum Sagepenum is made by melting 3 parts Asafetida with 1 5 parts Galbanum and adding 1 part Oil of Turpentine. Its uses are similar to Galbanum. 2822. Spruce Gum. — A Gum-Resin obtained from the black spruce, Abies Nigra, found in the elevated regions of New England and in Canada. This gum is highly esteemed as a chewing gum, the pure gum having a fine flavor, but, as it is not abundant, most of the gum sold as Spruce Gum consists mainly of Bergundy Pitch. An alcoholic Tincture of Pure Spruce Gum is used as a pectoral, and may be made into a syrup the same as Tolu. 2823. Tamarac Gum.— This is a Gum-Resin exuding from the tamarac or hackmatack tree, Larix Americana. It is not very abundant. It is used in the form of tincture as a pectoral, and the gum is chewed for the same purpose. Many other exudates which are known commercially as Gums will be found under other headings, as Benzoin, Liquidamber or Sweet Gum under Balsams, Elemi, Gum Thus or White Pine Gum, etc., under Oleo- Resins, etc. 2824. Chewing Gums. The practice of Gum chewing has recently developed to quite an extent among all classes, and enterprising manufacturers advertise the superior qualities of their Gums with great vigor. They can only be mentioned in this connection, their formulas being given in another department. The Chewing Gums sold as " Spruce Gum " are mainly composed of Burgundy Pitch. The white Gums under various titles as "Mastic," " Tolu," " Rosebud," etc., are soft Paraffin, some of them being mixed with sugar, fruits, etc. "Rubber Gum" is made from Rubber mixed with some other Gums. The Taffy and Caramel Gums are made with mixed Gums and Sugar or Caramel, etc. The Black Gums contain Black Pitch, etc. In fact, so great is the variety of Chewing Gums found in the market that it is next to impossible to enumerate them. RESINOIDS OR CONCENTRATIONS. 731 RESINOIDS OR CONCENTRATIONS. . Eclectic Extracts, Powders, or Active Principles. A class of preparations first introduced by the Eclectics and known as concentrated medicines or resinoids, of which Resin of Podophyllum (" Podophyllin ") may be taken as a type, are considerably used, many of them possessing great merit as representing the principles of the drugs from which they are derived in concentrated form. These preparations are gener- ally precipitated alcoholic extracts of the drugs, some being resins, some oleo-resins, and others mixed principles, which may or may not represent the true active medicinal value of the drug, depending upon its solubility in alcohol. They must not, therefore, be confounded with true active principles of definite chemical composition bearing the same names, as they are sometimes widely different. 2825. General Formula for Resinoids or Concentrations. Take of the required drug in moderately fine powder any convenient quantity and Alcohol sufficient. Exhaust the drug by water-bath percolation with the alcoholic menstruum and concentrate the percolate by distillation until it is reduced to the consistence of a thin syrup, which pour gradually and with constant stirring into a sufficient quantity of cold Water. After standing, collect the precipitate, wash it with a little cold water, spread it upon plates and carefully dry it by means of a current of warm air, or in the case of Oleo-resins, or very soft extracts which are precipitated, mix them with a suffi- cient quantity of the powdered drug from which they were derived, to make them into the form of powder. The consistence of the residue after concentration by distil- lation <>r evaporation depends much upon the constituents of the drug, but as a rule the liquid should be no more than one fourth the quantity of the powdered drug which was taken. And the quantity of cold Water into which it is poured should be from 10 to 30 times as much as of the concentrated liquid. Some extracts deposit tarry matter, which is undesirable, and 782 RESINOIDS OR CONCENTRATIONS. should be removed by allowing them to stand and decanting the clear solution before adding to Water. Alum is sometimes added to the Water to facilitate the precipitation. Asclepidin, CypHpedin, Ptelein, Scnccin, XantJioxylin and some other preparations are mostly Oleo-resins, and must be mixed with the powdered substances in order to make them into a powder. Some, like Leptandrin and Ergotin, are soft resinous substances and are much improved by the addition of a por- tion of the powdered substance. The following list embraces most of the Concentrations or Resinoids which are used, although it is obvious that many others may be made. They may be prepared as directed by the foregoing General Formula : ECLECTIC CONCENTRATIONS OR RESINOIDS. 2827 282S 2829 2830 2831 2832 2833 2834 2835 2836 2837 2838 2S39 2840 2S41 2842 2843 2844 2845 2846 2847 2848 2849 2850 285. 2852 2853 2854 2855 2856 2857 2858 2859 2860 2861 2862 2863 Aconitin , Aletrin Alunin , Ampelopsin.. . Apocynin , Asclepin Atropin , Baptisin Barosmin Betin Caulophyllin . Ceanothin Cerasein Chelonin Chimaphilin . Chionanthin . Cimicifugin . . Collinsonin . . Colocynthin .. Cornin Corydalin. . . . Cypripedin Di gitalin Diosconn Ergotin Erythroxylin . Euonymin . . . Eupatorin. . . . Euphorbin . . . Eupurpurin... Krazerin Gelsemin .... Geraniin Gossypiin Hamamelklin Helonin Hydrastin. . . . Hyoscyamin. . PREPARED FROM. PART USED. Aconitum Napellus Root. Aletris Farinosa Root Aluns Rubra Bark Ampelopsis Quinquefolia Bark Apocynum Androsaemifolium. . Root Asclepias Tuberosa Root Atropa Belladonna Root or leaves. . Baptisia Tinctoria Root Barosma Betulina Leaves Beta Vulgaris Root Caulophyllum, thalictroides . . . Root Ceanothus Americana Root Cerasus Virginiana Bark Chelona Glabra Herb Chimaphila Umbellata : Leaves Chionanthus Virginiana Bark Cimicifuga Racinosa Rhizome Collinsonia Canadensis Herb Cucumis Colocynthis Fruit Pulp Cornus Florida Root bark Dicentra Canadensis Tubers Cypripedium Pubescens Rhizome Digitalis Purpurea Leaves Dioscorea Villosa Root Ergota, Claviceps purpurea.. . . Fungus Erythroxylon Coca Leaves Euonymus Atropurpureus Bark Eupatorium Perforatum Leaves and tops. Euphorbia Corollata Root Eupatorium Purpureum Root Frasera Waited Root Gelseminum Sempervirens .... Rhizome Geraneum Maculatum Root Gossipium Herbaceum Root bark Hamamelidis Virginica Root Helonias Dioica Root Hydrastis Canadensis Rhizome Hyoscyamus Niger I Leaves & to 2 to 2 to V 2 to 35 to '.to 1 to 2 to U to 2 to 5 to 1 to 1 to 1 to 1 to 1 to Kto 3 to 5* to 1 to *to 2 tO IS tO M to 2 to V2 to 1 to 1 to l 2 to 2 to ■k grain. 5 grains. 3 grains. 8 grains. 2 grains. 5 grains. A grain. 1 grain. 4 grains. 5 grains. 1 g.ain. 5 grains. 10 grains. 2 giains. 4 grains. 3 grains. 5 grains. 3 grains. 2 grains. 5 grains. 2 grains. 2 grains, r grain. 5 grains. % grain. 3 grains. 4 grains. 4 grains. 2 grains. 3 grains. 5 grains. 2 grains. 3 grains. 5 grains. 5 grains. 2 grains. 5 grains. 2 grains. RESINOIDS OR CONCENTRATIONS. SACCHARA. 733 ECLECTIC CONCENTRATIONS OR RESINOIDS — Continued. No. NAME. PREPARED FROM. PART USED. DOSE. 2864 Inulin 2865 Irisin or Iridin . . . 2866 Jalapin 2867 Juglandin Inula Helenium Root Root Tub.r Root bark 1 to #to Kto 2 tO 2 tO 2 tO iV to I to 1 to 1 to 1 to t to ^to ^5 to 2 tO I to 1 to 2 tO I to 1 to K to 3 to 1 to 2 tO X A to 3 to tfto 1 to #to 3 grains. 2 grains. 2 grains. 5 grains. 5 grains. 4 grains. % grain. 3 grains. 3 grains. 5 grains. 2 grains. 5 grains. 1 grain. 1 grain. 5 grains. 3 grains. 3 grains. 4 grains. 3 grains. 2 grains. 2 grains. 5 grains. 3 grains. 5 grains. 1 grain. 5 grains. % grain. 2 grains. 1 grain. Leontodon Taraxacum. ....... Leptandra Virginica Lobelia Inflata Humulus Lupulus Lycopus Virginicus 2869 Leptandrin 2870 Lobelin 2871 Lupulin Herb Strobiles Plant Rhizome Root Bark Rhizome 2S73 Macrotin 2874 Menispermin Menispermum Canadense Myrica Cerifera Phitolacca Decandra Podophyllum Peltatum 2876 Phytolaccin 2877 Podophyllin Bark Root bark Bark... 2881 Rhein Rhus Glabra Root bark Root 2883 Rumin 2884 Sanguinarin Rumex Crispus Sanguinaria Canadensis Scutellaria Laterifolia Rhizome Herb Plant 2888 St llingin 2889Tri!liin 289x1 Veratrin 2891 Viburnin 2892 Xanthoxylin Trillium Pendulum Rout Rhizome Bark Viburnum Opulus Xanthoxylum Fraxineum Bark SACCHARA — SUGARS. Sugars arc substances composed of carbon, hydrogen and oxygen, of a sweet taste, crystallizable, and mostly of a vege- table origin. The most important sugars, are Saccharose, the ordinary Sugar of commerce, prepared from sugar-cane, sor- ghum, etc., and glucose, which has already been described (page 515). The glucoses have the composition C H 12 O 6 ,and are di- rectly subject to vinous fermentation. The saccharoses have the composition C, JLO, , , and arc fermentable only after being converted into a Sugar of the glucose: class. There are also a number of non-fermentable Sugars termed saccharoids, some of them having the same composition as glucose, and others varying somewhat. 734 SACCHARA — SUGARS. Among other products that are derived from the decompo- sition of Saccharine fluids, Alcohol, Acetic Acid and Oxalic Acid may be mentioned as most valuable. 2894. Saccharum. Sugar. The greater part of the Sugar found in the market is pre- pared from the expressed juice of the Sugar-cane, grown in the Southern States, the West Indies, and Central America. The Sugar-cane is crushed in mills, and the juice, which is about 80 per cent, of the whole, is expressed, a little lime and bisulphite of calcium added, then strained and evaporated to a thick syrup, which is placed in casks, allowed to crystallize and drained. In the larger manufacturing establishments the pro- cess employed is somewhat different, the vacuum pan being used instead of open evaporation, and the draining being ac- complished by "centrifugals," which by rapid motion separate the fluid from the solid portions. The process for making Sugar from Sorghum is the same, and Beet-Root Sugar is made in a similar manner, but is not so readily purified. The crude or "raw" sugars prepared as described are puri- fied and decolorized by filtering their solutions through pow- dered animal charcoal, or bone-black. When allowed to crys- tallize from the solution thus purified the crystals obtained are called Rock Candy, but if evaporated to a solid mass with continual agitation, it is granulated. Granulated Sugar, on account of its purity and convenience, is generally chosen for making syrups and liquid preparations, and powdered Sugar for making troches, powders, triturations, etc. Cane-sugar is often adulterated or mixed with Grape Sugar, which may be discovered by Trommer's test, which is as follows: Trommer's Test. — To a solution of the sugar or saccharine liquid desired to be tested, add a little solution of sulphate of copper, and then solution of potassa in excess ; heat the mixture to boiling. When cool, if the saccharine solution contained only saccharose or cane-sugar, there will be but a small deposit of red powder ; but if it contained grape-sugar or glucose, there will be a copious greenish precipitate, which changes to scarlet and afterward to a dark brownish-red. SACCHARA — SUGARS. 735 Saccharine Substances. The following substances, having similar composition and characteristics, are known as Saccharine substances : Saccharoses. C 12 Ho,O u . Cane-Sugar (Saccharose). — From sugar-cane, beets, and sorghum. Parasacc/iarose. — Produced by spontaneous fermentation of cane-sugar. Milk Sugar (Lactose, Lactin). — Obtained from milk. (See page 542.) Mycose. — Obtained from ergot, identical with trehalose. Melezitose. — Obtained from manna found in Tasmania and Persia. Melitose. — Obtained from various species of eucalyptus. Trehalose. — Obtained from cocoons of Larinus Maculatus. Glucoses. C H 12 O 6 . Glucose (Dextrose or Dextro-Glucose). — From starch, etc. (See page 515.) Ro- tates the plane of polarization strongly to the right. Grape- Sugar. — By crystallizing glucose. (See page 515.) Lcevulose (Lsevo-Glucose). — From sugar-cane and molasses. Rotates plane of polarization to the left. Maltose (Barley-Sugar). — By the action of diastase on starch. Dulcilose. — By oxidizing dulcit with nitric acid. Mannitose. — Found in muscular flesh. Galactose — By treating sugar of milk with dilute sulphuric acid. The following are the non-fermentable saccharine substances : Maunit — C 6 H 14 6 . — From manna and other similar substances. Dulcit — C 6 H 14 O c . — From meiampyrum nemorosum. Eucalyn — C 6 H 12 O . — From the fermentation of melitose. fnosil C H 12 O 6 . — From muscular flesh. Quercitrose — C c H 12 O . — From quercitrine. Sorbil — C H 12 O 6 . — From mountain ash berries. Erythromannil — C 12 H 30 O 12 . — From protococcus vulgaris. Isodulcit — C II 1 .,O . — From quercitrine. Piirit — C e H 18 B . — From pinus Iambertiana. Quercil — C c 1 1 , 2 5 . — From acorns. 2895. Saccharates are prepared by saturating sugar with tinctures, drying it, then powdering. Homoeopathic pellets are prepared in a similar manner, by saturating them with a tincture strongly alcoholic and allowing them to dry. 2896. Oleo-Saccharures — ElcBO-Sacchara — are prepared by rubbing 1 drop of any volatile oil wilh 30 grains of powdered sugar until they are thoroughly mixed. 2897. Saccharine.— This is a new substance prepared by a complicated process from Toluene, by treating with acids and ammonia. Its every-day 736 SALICINUM — SALICIN. SALICYL. chemical name is Benzoyl-Sulphonic-Imide, but when it is on dress-parade it is known as Anhydroorthosulpaminbenzoic Acid, its composition being C 6 H 4 COS0 2 NH. It is said to be about three hundred times sweeter than sugar, and to possess wonderful antiseptic properties. Its uses have not yet been well denned, but it is predicted to be of great value in sweetening preparations which with sugar would be liable to ferment, as fruit juices, etc. 2898. SALICINUM — SALICIN. C 13 H 18 7 . A neutral principle prepared from the bark of Salix of dif- ferent species, by treating a boiling concentrated decoction of the bark with Oxide of Lead until it becomes nearly colorless, the lead combining with the gum tannin and extractive mat- ter, which is removed by filtration. The filtered liquid is then treated with Sulphuric Acid to convert the dissolved Oxide of Lead into a sulphate, and then with Sulphide of Barium to remove sulphates, etc. The liquor is then filtered, evaporated, and crystallized, Salicin being obtained, Salicin is a Glucoside, which yields Saligcnin and Sugar when heated with dilute acids. Uses. — It is used as a febrifuge and tonic in doses of 5 to 30 grains. Some practitioners prefer it to quinine, especially in rheumatic fever. SALICYL. C,H 4 0. This is the hypothetical compound radical of the Salicyl series of compounds. It is not known as a free radical, but only in combination. The volatile Oil of Meadow Sweet, Spircea Ulmaria, is a natural hydride of Salicyl. Oil of Wintergreen and Oil of Birch are also compounds of Salicyl. 2899. Acidum Salicylicum— Salicylic Acid, — HC 7 H 5 3 . The greater part of the Salicylic Acid found in the market is made according to the pro- cess of Kolbe, by treating Carbolate of Sodium with Carbon dioxide (Car- bonic Acid gas) ; by this process it is made as follows : A highly concen- SALICYL. SANTONINUM — SANTONIN. 737 trated solution of Caustic Soda is evaporated with a corresponding amount of Carbolic Acid to a dry powder. This is then heated in a retort to ioo° C. (212 F.) and a current of dry carbon dioxide passed over it. The tempera- ture is gradually increased to 180 C. (356 F.) and then to 220 C. (428 F.), at which temperature the free Phenol distills over. The temperature is then increased to 250 C. (482 F.) and continued until no more Phenol dis- tills. Half of the Phenol used now remains in the retort as Salicylate of Sodium, the other half having been recovered by distillation as Phenol. The Sodium Salicylate thus obtained is dissolved in water, decomposed by the addition of Hydrochloric Acid, the precipitate washed and crystallized from its solution in hot water, then drained and dried, making the Salicylic Acid of commerce, which may be termed Pheno-Salicylic Acid. A Salicylic Acid in much larger crystals is also prepared from Oil of Win- tergreen, but is too expensive for general use. It is known as Gaulthero- Salicylic Acid, and has the same chemical composition as that previously described. It forms with bases a class of Salts called Salicylates. Uses.— Salicylic Acid is employed extensively as a preservative of non-al- coholic liquids, fruits, etc., and in medicine is used as a remedy for rheum- atism, neuralgia, and septic diseases, and in large doses as an antipyretic. The dose is from 5 to 1 5 grains. 2900. Salicylous Acid — C 7 H 6 3 — Salicylol. This is an oily liquid, ob- tained from Volatile Oil of Meadow Sweet, which, when pure, consists en- tirely of it. It is also obtained from Salicin. It is not employed in medicine. 2901. Salol. — This new antiseptic and antipyretic is a phenyl ether of Salicylic Acid, its chemical formula being C C H 5 .C 7 H 5 3 . The process for making it is complicated, but it is claimed that it possesses the valuable medicinal properties of Salicylic Acid without its disagreeable effects. It is given for rheumatism, fevers, etc., in doses of 5 to 20 grains, with excellent results, and also applied as a dusting powder for eruptions, sores, etc. 2902. SANTONINUM -SANTONIN. C ]5 H 18 0. r A neutral crystalline principle prepared from Santonica. A formula for its preparation is official in the Br. P., as follows: Santonica, bruised 1 pound av. Slacked Lime, 7 ounces av. Hydrochloric Acid, a sufficient quantity. Solution of Ammonia ^ fi. ounce. Rectified Spirit, 14 fl. ounces. Purified Animal Charcoal 60 grains. Distilled Water, a sufficiency. f38 SANTONINUM — SANTONIN. SAPOES — SOAPS. The bruised " Worm Seed " is boiled first with I gallon (Imperial) of Water and 5 ounces of the Lime for an hour; the liquid is then strained off with pressure and the residue again boiled for half an hour with half a gallon (Imperial) of Water and 2 ounces of the lime, and the liquid strained with pressure as before and added to the portion previously obtained. The liquid is then allowed to settle, strained, and evaporated to 2^ pints (Imperial). To this,, while hot, Hydro- chloric Acid is added until the liquid is slightly acid and set aside for 5 days to precipitate. The liquid is then poured off from the precipitate, which is washed first with cold Water, then with the Solution of Ammonia diluted with 5 ounces of cold Water. It is then pressed, dried, and mixed with the Animal Charcoal, 9 fl. ounces of the Spirit added, and, after half an hour, the mixture boiled for 10 minutes. It is then filtered while hot and the residue in the filter washed with an ounce of boiling spirit and the liquid set aside to crystallize. The crystals are then collected, dissolved in 4 ounces of boiling Spirit and recrystallized. It should be protected from the light, which changes it yellow. Uses. — Santonin is employed in medicine as an anthel- mintic in doses of 1 or two grains. It is best given in the form of powder or suspended in syrup or emulsion, or in the form of troches. The worm confections and lozenges which are popular contain Santonin. SAPOES — SOAPS. Soaps are compounds of fatty acids with alkalies, and are prepared by mixing fats or oils with a caustic alkali in solution, and either boiling until a thick mass is formed or combining cold, and allowing to stand until the combination is effected. The use of Soaps in the arts and industries is well known. In pharmacy and medicine they are considerably employed. Soaps are naturally divided into hard soaps, which are made with soda alkali, and soft soaps, which are made with Potassa alkali. As different fats vary in proportion of their fatty acids, and the caustic soda and potassa of commerce vary in caustic SAPOES — SOAPS. 739 strength, definite formulas for the Soap bases cannot well be given, but the following general formulas and processes given by W. J. Menzies in the Manufacturers Review for November 15, 1880, will be satisfactory. The first can be used either for making Castile Soap or Curd Soap : 2903. General Formula for Hard Soaps. Take exactly 20 pounds of Greenbank double refined 98 per cent, pow- dered caustic soda ; put it into any suitable iron or metal vessel with 90 pounds of soft water, stir it once or twice with a stirrer ; it will dissolve immediately and become quite hot ; let it stand until the lye thus made is cold. Weigh out and place in any convenient vessel for mixing and melting exactly 145 pounds of clean tallow, grease or oil (where oil is used no heat- ing is required). Melt it slowly either with steam or fire until it is liquid and feels warm to the hand — that is to say, not exceeding ioo° F. Pour the lye slowly into the melted tallow in a small stream continuously, at the same time stirring with a flat wooden stirrer about three inches broad ; continue gently stirring until the lye and melted tallow or oil are thoroughly combined and the mixture appears like honey. Do not stir too long, or the mixture is liable to separate again. The time required varies somewhat with the weather and kind of tallow, grease or oil used, from fifteen to twenty minutes will be quite enough. When the mixture is complete, pour it off into an ordinary soap frame ; or this may be dispensed with, and an old square wooden box may be used for a mould, previously damping the sides with white wash or water so as to prevent the soap sticking. Put the frame or box in a warm place until the next day, covering it up well with blankets ; it will then be found to contain about 255 pounds of fine white hard soap, which can be cut up with a wire into bars for the convenience of weighing, etc. Remember the chief points in the above directions, which must be exactly followed. The lye must be allowed to cool. The heated tallow or grease used must hot be over a temperature of about ioo° F. The lye must be thoroughly stirred into the melted tallow, not tallow or oil into the lye. The exact weights of Double Refined Powdered 98 per cent. Caustic Soda and tallow, grease or oil must be taken. If the tallow or grease is not clean or contains any salt, it must be " rendered " or purified previous to use, that is to say, boiled with water and allowed to cool, as any salt present spoils the whole operation entirely. Discolored or rancid grease or tallow, however, is just as good for common soap-making purposes. If the soap turns out streaky and uneven, it has not been thoroughly mixed. If very sharp to the taste, too much caustic soda has been used. If soft, mild and greasy, too much tallow or oil has been taken. In either case it should now be thrown into a kettle with about six gallons of water and cut up into shavings or very small pieces. In the first case boiling is all that is necessary — in the other instances a very little more oil or a very little more of the Double Refined 98 740 SAPOES — SOAPS. per cent. Caustic Soda must be added to the water previous to boiling. None of these things will happen, however, if the above directions are exactly fol- lowed, and with the experience gained after making a few batches of soap the whole process is an exceedingly easy one. 2904. General Formula for Soft Soap. Take 50 pounds of Greenbank pure caustic potash ; put it in any iron or earthenware vessel with 90 pounds of water. Stir it once or twice ; it will dissolve immediately and become quite hot. Let it stand until the lye thus made is cold. Place in any convenient vessel for mixing 185 pounds of cot- tonseed oil and 20 pounds of clean melted tallow. Pour the lye into the oil in a small stream, at the same time stirring with a flat wooden stirrer about three inches broad. Continue gently stirring until the lye and oil are thor- oughly combined, and in appearance like honey. Now cover the vessel up and put it in a warm place until the next day. The oil and lye will then be found nearly all combined. Stir up well again and leave for a few days, when the mixture will become quite even and the saponification complete ; the result being the production of about 345 pounds of very stiff potash soap, costing for materials about 3X cents per pound. If made for use by an actual consumer nothing more need be done ; the requisite quantity can be thrown into the scouring vat, either with or without the addition of a small quantity of carbonate potash to increase the alkali present, and depending upon the purpose for which the soap is used. The potash soap produced in this way is very much more concentrated than the ordinary" fig " soap hitherto sold. If it is desired to make an ordinary soft soap it can be produced in the following manner : Take 200 pounds of the stiff potash soap and add to it about 70 pounds of water. Put it into a boiling pan and gently heat and stir it so as to mix well together ; at the same time adding about eight pounds of crystalline carbonate of potash, which will remove all " stringyness " and produce a clear homogeneous soap. It will improve in appearance by keeping for a short time. The above "cold process " is simple and effective, and even a few pounds alone of soft soap can be made by it. With mechanical mixing apparatus and large pans, soft soap can easily be produced on a large scale by this process. The following are the Soaps of the U. S., Br. and German Pharmacopoeias : 2905. Sapo. U. S. White Castile Soap. Soap prepared from Soda and Olive Oil. In Br. pharmacy this is known as Sapo Duris, or Hard Soap ; in German pharmacy it is known as Sapo Oleaceous ; but in commerce it is known only as Castile Soap. SAPOES — SOAPS. 741 The common varieties made from inferior oil and mottled by the addition of an iron salt are extensively sold as ordinary Castile Soap, but in medicine and in pharmacy only that made with fine Olive Oil and pure Soda should be used. It is employed for making oleates, liniments and pills, and is exten- sively used mixed with other kinds of Soap for making perfumed and toilet soaps. 2906. Sapo Animalis. Br. Curd Soap. A Soap made with Soda and purified animal fat, consisting principally of stearin. This is a nearly neutral White Soap, generally made with fine tallow and pure soda alkali or caustic soda. It is known as Tallow Soap, and used as the basis of most of the perfumed toilet Soaps. In pharmacy it is used in making several plasters, liniments, pills, and suppositories. For making fine Toilet Soaps, Curd Soap is reduced to shavings by passing over a plane and then, being moistened, it is combined with the perfuming oils desired, by working them well in with it in a mortar, until the mass is of uniform consistence without streaks. For larger manufacturing the Soap is milled with the oils, and then pressed into cakes. If desired to be colored the coloring matter is well worked in. 2907. Sapo Jalapinus. G. P. Jalap Soap. The G. P. gives the following formula for Jalap Soap or Jalapenseife : Resin of Jalap, 4 parts. Medicinal Soap 4 parts. Diluted Alcohol 8 parts. Dissolve the Resin of Jalap and Medicinal Soap in the Diluted Alcohol, and evaporate on a steam-bath, stirring constantly, to 9 parts. 2908. Sapo Mollis. Br. Soft Soap. Made with Potash and Olive Oil. In Br. pharmacy it is used in making turpentine liniment. It is of a gelatinous consistence, and is soluble in recti- fied spirit. The Sapo h'alinus of the G. P., which is known as Potassa Soap or Soft Soap, is made by adding to solution of Potassa, G. P., 135 parts, heated on a steam-bath, Linseed Oil 100 parts, stirring constantly, and continuing the heat for half an hour ; then adding Alcohol, 25 parts, stirring, and gradually adding Water, 200 parts, and heating until a transparent viscid soap is formed, and continuing the heat until the Alcohol is evaporated, and the finished product weighs 150 parts. This is a soft lubricous mass, and differs from the Soft Soap of the Br. P. in being transparent. 742 SAPOES — SOAPS. 2909. Sapo Medicatus. G. P. Met lit i)i a I Soap. The German Pharmacopoeia directs : Solution of Soda, G. P., 1 20 parts. Lard, 50 parts. 50 parts. 12 parts. Olive Oil, Alcohol, . Water 280 parts. Chloride of Sodium 25 parts. Carbonate of Sodium 3 parts. Heat the solution of Soda by means of a steam-bath, and gradually add the Lard, previously melted, then the Olive Oil ; stir and continue the heat for half an hour; then add the Alcohol, and then 200 parts of Water, grad- ually adding, if necessary, small portions of the solution of Soda until a transparent viscid Soap is formed ; then add a filtered solution of the Chloride and Carbonate of Sodium in 80 parts of Water, and heat and stir until the Soap has wholly separated from the liquid. The separated Soap is afterward washed, expressed, and cut into cakes, and is used as a neutral Medicinal Soap. 2910. Sapo Viridis. U. S. Green Soap, Soap prepared from Potassa and Fixed Oils. This is a Soft Soap, called in the G. P. Sapo Kalimcs Venalis. It is prepared from various Oils, which contain but little stearin, by boiling with solution of Potassa. It is used in pharmacy in making Tincture of Green Soap, and medicinally in skin diseases. Other Soaps. The foregoing are all the Soaps official in the leading phar- macopoeias, but a large variety of other Soaps are used in pharmacy and the toilet, the more important medicinal soaps being here mentioned. 2911. Yellow Soap. — This is the common Laundry Soap, made from tallow, resin and lard, with Soda, the same as curd soap. 2912. Marine Soap, or Salt- Water Soap. — This is a Coconut Oil Soap, made with Soda, and containing an excess of alkali. It is used for washing in salt water and for making toilet soaps. It is known also as Coconut Soap. 2913. Palm Soap.— This is a yellow soap, made with Palm Oil and Soda, considerably used for mixing in making toilet soaps. SAPOES — SOAPS. 743 2914. Naples Soft Soap is made from Fish Oil mixed with Olive Oil with Potash alkali. Fig Soft Soap is made with Olive and other Oils and Potash. 2915. Whale Oil Soap is made with common Whale Oil and Potash. It is also called Black Soap, and is used chiefly for washing plants to remove insects. The foregoing are used as bases and for combining to make other soaps. A few medicinal soaps have some sale and use, especially Carbolic, Sulphur, and Tar Soaps. 2916. Arsenical Soap. — Carbonate of Potassium 6 ounces, Arsenic, White Soap, each 2 ounces, Powdered Camphor 3 drachms, Water sufficient to make a stiff paste. This is used for preserving the skins of birds and small animals. 2917. Antimonial Soap.— Golden Sulphuret of Antimony 2 drachms, Solution of Caustic Potassium 6 drachms. Dissolve the salt in the solution, and mix thoroughly with Castile Soap, in powder, 1%. ounce. 2918. Camphorated Soap.— This Soap is usually prepared by incorpo- rating from 2 to 5 per cent, of Camphor with Curd Transparent Soap. The Camphor is dissolved in as little Alcohol as possible, and added to the melted Curd or Transparent Soap, the Alcohol evaporating and leaving the Camphor mixed with the Soap. It may also be mixed by melting powdered Camphor with Soap. 2919. Carbolic Soap. — This popular Soap maybe made for toilet pur- poses by incorporating 2 to 3 per cent, of Carbolic Acid by melting with Curd or Castile Soap. For medicinal and surgical use it is usually made about 5 per cent, by incorporating with White Castile Soap. For veterinary use and as a wash for dogs and other animals to remove vermin, it is generally made with 10 per cent, of Crude Carbolic Acid, mixed with any kind of cheap hard soap. 2920. Chlorinated Soap.— Powdered Castile Soap 11 ounces, dry Chlo- rinated Lime 1 ounce. Mix them together and make into a mass with Alco- hol, in which some perfume has been dissolved. This is used as a detergent and antiseptic in hospital practice. 2921. Cod Liver Oil Soap.— This may be made with Cod Liver Oil 2 ounces, Caustic Soda 2 drachms, Water 5 fl. drachms. 1 drachm of Iodide of Potassium may be added to this ; making a valuable Soap for scrofulous and syphilitic sores. It is also given internally. 2922. Croton Oil Soap. — Croton Oil and Solution of Potassa, equal parts, triturated together in a warm mortar until they combine. This is given as a cathartic, in doses of 1 to 3 grains, and is much less irritating than the oil taken alone. 2923. Glycerin Soap.— For medicinal use any good toilet, transparent, or Curd Soap may be made by melting with a very little water, and mixing 744 SAPOES — SOAPS. thoroughly with from 3 to 5 per cent, of Glycerin. It may be perfumed as desired. The following formula may be used if desired to make the Soap from crude materials : 40 pounds of Tallow, 40 pounds of Lard, and 20 pounds of Coconut Oil are saponified with 45 pounds of Soda Lye and 5 pounds of Potash Lye of 40 Baume ; to the saponified mass 6 pounds of Glycerin, l / 2 ounce Oil of Portugal, yi ounce Oil of Bergamot, 5 ounces Oil of Bitter Almond, and 3 ounces Oil of Vitivert are added. 2924. Iodine Soap. — This may be made by melting Castile Soap, 1 pound, and adding while melted 1 ounce of Iodide of Potassium, dissolved in 3 ounces of Water. It is used for scrofulous and syphilitic sores. 2925. Juniper Tar Soap. — This Soap may be prepared by saponifying Juniper Tar 1 part, mixed with Tallow 4 parts, with a solution of Caustic Soda, in the same manner as is directed for making Curd Soap. Other Tar Soaps may be made in the same general manner, care being used not to have them contain an excess of alkali. The Tar Soaps are highly esteemed in skin diseases. 2926. Mercurial Soap. — This is made by saponifying Nitrate of Mercury Ointment with a solution of Caustic Soda. It is employed for some skin diseases. White Precipitate Soap may be made by incorporating 1 drachm of White Precipitate with 6 ounces of Curd or other White Soap. Red Precipitate Soap may be made with double the quantity of Red Pre- cipitate, as directed above. Corrosive Sublimate Soap may be prepared with Castile Soap, in powder, 4 ounces, Corrosive Sublimate, in fine powder, 60 grains, Alcohol 1 fl. ounce, all well beaten together. 2927. Sulphur Soap. — This Soap may be prepared by incorporating 5 per cent, of Precipitated Sulphur (see Sulphur) with Curd Soap while making. Alum-Sulphur Soap may be made by using 1 per cent, of Alum and 5 per cent, of Sulphur in the same manner. Sulphur Soap is a popular remedy for skin diseases. 2928. Transparent Soap. — By cutting dry Curd, Castile or other varieties of Soap in fine shavings, and dissolving in an equal weight, or as little as possible, of Alcohol, and after standing for some time until all is dissolved that will, then pouring off the clear portion and casting in moulds, and drying. No more spirit than is necessary should be used. It may be perfumed as desired. 2929. Turpentine Soap.— This may be made by mixing Carbonate of Potassium, Oil of Turpentine and Venice Turpentine, equal parts, in a warm mortar, adding a little water until they are combined. This is a stimulating soap for washing indolent ulcers, etc. The foregoing Soaps include nearly all that are used to any extent medic- inally. Other Soaps will be found among the toilet preparations. SELENIUM. SILICON. 745 SELENIUM. Symbol, Se. ; Atomic weight, 78.8. Selenium is a rare elementary substance discovered in 1817, by Berzelius, in the refuse of the manufacture of sulphuric acid from pyrites of Fahlun in Sweden. Like sulphur it assumes three allotropic forms — amorphous, vitreous, and crystalline. It combines with oxygen and with hydrogen and some other elements, but its compounds are not used in pharmacy. 2930. Selenic Acid — H 2 Se0 4 . — This is prepared by fusing Selenium with Nitrate of Potassium or Sodium, treating the fused mass with Water, precipitating the solution thus made with Nitrate of Lead, and then decom- posing the precipitated Selenate of Lead with Sulphuretted Hydrogen, and separating the liquid, which is Selenic Acid, from the precipitate. This Acid unites with bases forming Selenates. 2931. Selenous Acid — H 2 Se0 3 . — This may be made by heating the foregoing rapidly. SILICON. Symbol, Si ; Atomic weight, 28. Silicon is an element classed chemically with Carbon and Boron, and like them is found in three allotropic states — amor- phous, crystalline, and graphitoidal. It is found abundantly in nature combined with earths, and in the form of sand, flint, quartz, etc., as an anhydride (silica), which is its only oxide. 2932. Silica — Si() 2 . — This may be obtained most conveniently by de- composing the solution of Silicate of Sodium (1919) with Hydrochloric Acid, washing and drying the precipitate. It is a tine white powder, insoluble in all acids except hydrofluoric. It is an anhydride, but more frequently called Silicic Acid. It is soluble in strong alkali solutions by the aid of heat, form- ing salts called Silicates, as Silicate of Sodium, Silicate of Potassium, etc. In the crystalline form Silica is found in agate, amethyst, calcedony, corne- lian, onyx, etc., colored variously by admixture with other substances. In the form of sand and quartz, Silica is extensively employed in the manufacture of glass, being fused with soda ash or other alkali. 746 SODIUM OR NATRIUM. SODIUM OR NATRIUM. Symbol, Na. ; Atomic weight, 23 ; sp. gr., 0.972. Sodium is one of the Alkali metals, having the same general characteristics as potassium. It is silver-white, soft, fuses at 194 F., is volatilized at a red heat and oxidizes rapidly in con- tact with the air, having to be preserved in some hydro-carbon, as mineral naphtha. Thrown upon water it decomposes it with great violence but without flame, differing in this respect from potassium. It is prepared in the same manner as potassium (which see), and is the basis of the Sodium salts, combining with all acids and negative elements to form them. The salts of Sodium are all white, crystallizable, readily soluble, and are of great importance in the arts and in medicine. The following are the salts of Sodium official in the leading pharmacopoeias : 2 933 Soda, U. S. Soda Caustica. Br. Soda — Hydrate of Sodium — Caustic Soda. NaHO. Caustic Soda as it is termed in trade is an article of great commercial importance, and is extensively used in the arts and industries of the world. It is prepared of several degrees of strength for manufacturing purposes, being from 60 to 98 per cent, pure, and is furnished in drums or smaller packages, either in a solid mass, granulated, or in powder. For medici- nal use it is usually prepared by evaporating the solution of Soda, and casting in sticks in the same manner as is directed for making Potassa (which see). Uses. — Caustic Soda is extensively employed for making soap and many other articles of commercial importance. In pharmacy it is used for making Solution of Soda, and for other purposes. In medicine it is used as a caustic and given in solution greatly diluted. SODIUM OR NATRIUM. 747 2934. Soda Tartarata. Br. Tartarated Soda — RocJielle Salt. NaKC 4 H 4 6 . 4 H 2 0. This is the British title for Potassii et Sodii Tartras, U. S., or Rochelle Salt, the process for making it being given under the U. S. title, which see (2424). 2935. Sodii Acetas. Acetate of Sodium — Natrium Aceticum. NaC 2 H 3 2 .3H 2 0. This salt may be prepared by neutralizing Acetic Acid with Carbonate of Sodium, filtering the solution, concentrating by evaporation, and crystallizing. By continuing the evapora- tion, with stirring, it may be obtained granulated, in which form it is more convenient for pharmaceutical use. Uses. — Acetate of Sodium is used in pharmacy for making many other salts by double decomposition, and in medicine is much esteemed as a diuretic. The dose is from 20 to 60 grains. 2936. Sodii Arsenias. Arseniate of Sodium. The formula and process for making this salt will be found on page 178, which see. 2937. Sodii Benzoas. Benzoate of Sodium — Natrium Bcnzoicum. NaC 7 H 5 2 .H 2 0. This salt may be prepared by adding Benzoic Acid to a hot concentrated solution of pure Carbonate of Sodium as long as effervescense occurs, then evaporating to dryness and granulating by stirring, or by crystallizing from the solution. Uses. — This salt is used in the treatment of rheumatism, and some kidney diseases. Also in septic diseases in doses of 20 to 60 drains. 748 SODIUM OR NATRIUM. 2938. Sodii Bicarbonas. Bicarbonate of Sodium — Natrium Bicarbonicum — " Baking Soda." NaHC0 3 . Commercial Bicarbonate of Sodium is prepared by saturat- ing Carbonate of Sodium with Carbonic Acid gas. As thus prepared it contains some impurities which are not desirable for medicinal use, the U. S. P. directing that the official salt shall contain 99 per cent, of Bicarbonate of Sodium. This may be made from the commercial salt by percolating 2 pounds av. with three pints of water, which dissolves out the impurities; the residue left in the percolator is then dried on blotting paper. For most purposes, however, the commercial salt is employed. Uses. — Bicarbonate of Sodium is used for making many pharmaceutical preparations, and in medicine as an Anti-acid. In making aerated waters it is a convenient source of Carbonic Acid gas, which is liberated when it is decomposed. 2939. Sodii Bisulphis. Bisulphite of Sodium. NaHS0 3 . The salt is prepared by passing Sulphurous Acid gas into a solution of Carbonate of Sodium until saturated, then evapor- ating and crystallizing. Uses. — In the arts this salt is extensively used for treating fabrics after bleaching with chlorine to neutralize excess. In medicine it is used as an antiseptic and antiferment in doses of 5 to 10 grains. 2940. Sodii Boras. Borax — Borate or Bi-borate of Sodium. This salt is described on page 199, which see. SODIUM OR NATRIUM. 749 2941. Sodii Bromidum. Bromide of Sodium. NaBr. This salt may be prepared according to the Br. P. in the same manner as is directed for making Bromide of Potassium, only using Solution of Soda instead of Solution of Potash, and being crystallized from warm solutions. It may also be pre- pared by decomposing Ferrous Bromide with Sodium Carbon- ate, Carbonate of Iron precipitating, and leaving Bromide of Sodium in solution which may be obtained by evaporating and crystallizing. Uses. — This salt is used for the same purposes as Bromide of Potassium, but is thought to be less irritating to the stomach. The dose is 30 to 60 grains. 2942. Sodii Carbonas. Carbonate of Sodium. Na 2 C0 3 .ioH 2 0. Soda Ash is an impure Carbonate of Sodium prepared by first converting common salt into Sodium Sulphate by treating with Sulphuric Acid, and then by heating the Sodium Sulphate with Calcium Carbonate (Limestone) and fine coal, which de- composes the Sulphate of Sodium, forming insoluble Sulphate of Calcium and soluble Sodium . Carbonate, which is dissolved out, evaporated to dryness and further carbonated by calcin- ing with one-fourth its weight of sawdust. This mass is then redissolved in water and the solution evaporated to dryness, which forms the Soda Ash of Commerce, an article of great commercial importance in the manufacture of paper, glass, etc. Carbonate of Sodium is prepared from Soda Ash by lixivation and crystallization, Soda Ash containing about 50 per cent, of commercial Carbonate of Sodium. It is also prepared by the Ammonia process, and by the Cryolite process, the resultant product being the same. Uses. — It is extensively employed in the industrial arts, and is the source of mosl of the sodium salts. It is seldom given in medicine except in combination. The dose is 5 to 20 grains. 750 SODIUM OR NATRIUM. 2943. Sodii Carbonas Exsiccatus. Dried Carbonate of Sodium. This is prepared by breaking the salt into small fragments and allowing it to effloresce by exposure to warm air for seve- ral days, then heating it to 45 C. ( 1 1 3 F.) until it has been converted into a white powder weighing only one half as much as the quantity taken, it is then passed through a fine sieve. The Br. P. directs 8 ounces of Carbonate of Sodium in crystals to be dried until vapors cease to be evolved, leaving a residue of about 3 ounces, entirely deprived of water, Na 3 C0 3 . Uses. — This is better for some uses in pharmacy than the crystallized salt, as its water of crystallization is driven off. It is used for making into pills and powders. The dose is 5 to 10 grains. 2944. Sodii Chloras. U. S. Chlorate of Sodium. NaC10 3 . This salt may be prepared by decomposition between Acid Sodium Tartrate in solution, and Chlorate of Potassium in solution. Acid Potassium Tartrate is precipitated and Chlor- ate of Sodium remains in solution. The filtered solution is evaporated and crystallized. Uses. — This may be used for the same purpose as Chlorate of Potassium, and is preferable for solutions, being more soluble. The dose is 10 to 20 grains. 2945. Sodii Chloridum. Chloride of Sodium — Salt. NaCl. This is one of the most abundant and widely distributed of natural salts. It is found in beds and mines as rock salt, and in solution in sea-water and salt springs and wells obtained by drilling, from which it is separated in crystalline form by SODIUM OR NATRIUM. 751 evaporation. It is extensively used for various industrial purposes and as a seasoning and preservative of food. In pharmacy it is employed as a source of Chlorine, and in medi- cine is used as a styptic and for some other purposes. 2946. Sodii Citro-Tartras Effervescense. Br. Effervescing Citro -Tartrate of Sodium. This is made according to the Br. formula as follows : Bicarbonate of Sodium, ... 17 ounces or parts. Tartaric Acid, in powder, . . 9 ounces or parts. Citric Acid, in powder, ... 6 ounces or parts. Refined Sugar, in powder, . . 5 ounces or parts. Mix the powders thoroughly, place them in a dish or pan of suitable form heated to between 200 and 220 F., and when the particles of the powder begin to aggregate, stir them assiduously until they assume a granular form ; then, by means of suitable sieves, separate the granules of uniform and most convenient size and preserve in well stopped bottles. Uses. — This is an effervescing salt when added to water, and is used as a refrigerant. It is given 60 to 120 grains in part of a glass of water. 2947. Sodii Hypophosphis. HypopJiospJiitc of Sodium. NaH 2 P0 2 .H s O. This salt may be most conveniently prepared by adding Carbonate of Sodium to solution of Hypophosphite of Cal- cium as long as a precipitate of Carbonate of Calcium is formed, then filtering and evaporating to dryness by heat of a steam- bath, stirring constantly to granulate the salt. Uses. — This is similar in medicinal properties to other hypophosphites, and is much used in making syrups and solu- tions of Hypophosphites Compound, the dose being 5 to 10 grains. 752 SODIUM OR NATRIUM. 2948. Sodii Hyposulphis. Hyposulphite of Sodium. Na 2 S 2 3 .5H 2 0. This salt is prepared from alkali waste by decomposing its Soluble Thiosulphate of Calcium, with Sulphate or Carbonate of Sodium. Uses. — It is a cheap sodium salt used for tanning, paper- making, etc., and by photographers, and in other arts. In medicine it is employed as an alterative and resolvent, in doses of 10 to 30 grains. 2949. Sodii Iodidum. Iodide of Sodium. Nal. This may be made in exactly the same manner as Iodide of Potassium, except the Solution of Soda must be used instead of Solution of Potassa. It may also be made by decomposing a solution of Ferrous Iodide with Carbonate of Sodium, the solution being filtered, evaporated and crystallized. Uses. — Its uses are similar to Iodide of Potassium, the dose being 5 to 15 grains or more. 2950. Sodii Nitras. Nitrate of Sodium — Natrium Nitricum. NaN0 3 . This is a native salt obtained from Chili and Peru and quite extensively sold as Chili Saltpetre. Being the cheapest source of nitrates it is extensively used for making Nitric Acid and some other preparations. Uses.— Its uses are similar in medicine to Nitrate of Potassium, but it is not considered so effective. The dose is 10 to 20 grains. SODIUM OR NATRIUM. 753 2951. Sodii Phosphas. Phosphate of Sodium — Natrium Phosphor icum. Na 2 HP0 4 .i2H 2 0. This may be prepared by adding a solution of Carbonate of Sodium to a solution of Acid Phosphate of Calcium prepared from a mixture of Bone-Ash and Sulphuric Acid. The follow- ing working formula shows the preparation of the Acid Phos- phate, and also of the Sodium Salt. The Acid Phosphate is first prepared and then the Sodium Salt : Bone-Ash, 16 ounces av. Sulphuric Acid, 10 ounces av. Carbonate of Sodium, \ yj j each a sufficient quantity. Mix the powder with the Sulphuric Acid in an earthen vessel, and add 1 pint of water. Stir thoroughly and allow to stand three days heated moderately, with occasional stirring and addition of water to make up for evaporation ; then add a pint of boiling water, pour the mixture on a muslin strainer and gradually add more boiling water until the liquid passes nearly tasteless. Mix the liquids obtained and set aside to settle, then pour off the clear portion and evaporate to a pint. This is a solution of Acid Calcium Phosphate, containing some Sulphate of Calcium, which is mostly precipitated upon cooling. Let cool, pour off the liquid from the deposited salt, and heat the liquid again in a porcelain vessel ; to this add gradually a concentrated solution of Carbonate of Sodium so long as effervescense ensues, then filter and set aside to crystallize, the crystals being Phosphate of Sodium, and the Neutral Phosphate of Ca/cium is precipitated as a white powder. Uses. Phosphate of Sodium is considerably used in phar- macy to prepare other phosphates, by double decomposition, and is given as a cathartic in doses of % to ] ounce. The Acid Phosphate of Calcium in solution as above prepared when diluted is the basis of the Acid Phosphates. Liquor Acidi Phosphorici Compositum may be made by taking of this solution 1 pint, Water 2 pints, Phosphate of Sodium 2 ounces av., Carbonate of Magnesium ' unce av., Phos- 754 SODIUM OR NATRIUM. phate of Iron (scale salt) I ounce av., dissolving and filtering. If wanted without Iron the Iron Salt may be omitted. This is used as a nerve tonic, and for making syrup for soda water, I ounce being added to a pint of syrup. 2952. Sodii Pyrophosphas. U. S. Pyrophosphate of Sodium. Na 4 P 3 7 .ioH 3 0. This is prepared by heating Phosphate of Sodium in a suit- able vessel to redness. It first melts, losing its water of crystallization by evaporation, only 40 per cent, of the salt remaining. The heat is then increased to 300 C. (572 F.), at which temperature it is converted into tribasic phosphate, or Pyrophosphate. This residue is then dissolved in water, the solution filtered, and the salt crystallized, making Pyro- phosphate of Sodium. Uses. — This is used in making Pyrophosphate of Iron, but is not employed in medicine. 2953. Sodii Salicylas. Salicylate of Sodium. 2NaC 7 H g 3 .H 2 0. This is most conveniently prepared from Salicylic Acid by mixing 100 parts with water to form a paste; then adding 104 parts of pure crystallized Carbonate of Sodium reduced to a moderately fine powder. The reaction proceeds with efferves- cense caused by escaping Carbonic Acid gas. The solution is then strained, heated in a porcelain capsule until all gas is expelled, made neutral by the addition of either Salicylic Acid or Carbonate of Sodium, and evaporated at a low heat to dryness. The method of preparing this from phenol is described under Salicylic Acid, which see. Uses. — This salt is much used as a remedy for rheumatism and neuralgia, in doses of 15 to 30 grains, and in pharmacy for making other Salicylates. SODIUM OR NATRIUM. J55 2954. Sodii Santoninas. Santoninate of Sodium. 2NaC 15 H 19 4 . 7 H 3 0. This may be prepared by adding to 4 fl. ounces of solution of Soda 1 fl. ounce of Water and mixing with the solution 1 ounce av. of Santonin, heating and stirring until the salt is dissolved, then filtering and setting aside to crystallize. More crystals may be obtained by further concentration and crystal- lization. Uses. — This salt is sometimes used instead of Santonin as an anthelmintic, being more soluble, but it possesses no advantage over it. The dose is I to 3 grains. 2955. Sodii Sulphas. Sulphate of Sodium — Glauber s Salt. Na 2 S0 4 .ioH 2 0. This salt is more familiarly known as Glauber's Salt, and is obtained most altogether as a by-product of the manufacture of other chemicals. It may be readily made by adding Sul- phuric Acid to a solution of Carbonate of Sodium until it is neutralized, evaporating and crystallizing. Uses.— It is used in making other preparations and as a " physic " for horses and cattle. It is also preferred by some to Epsom Salts as a cathartic in doses of half to one ounce. 2956. Sodii Sulphis. Sulphite of Sodium. Na 2 S0 3 .7H 3 0. This may be most conveniently prepared by passing Sul- phurous Acid gas through a concentrated solution of Carbon- ate of Sodium until it is completely saturated and Acid Sodium Sulphite is formed. To this an equal weight of Car- bonate of Sodium is then added, making a solution of the neutral Sulphite of Sodium, which when evaporated with con- stant stirring to dryness yield Sulphite of Sodium as a granu- 756 SODIUM OR NATRIUM. lar salt, which is preferred for medicinal use. A crystallized salt is also obtained by crystallizing from the solution. Uses. — This salt is used in the preparation of some phar- maceuticals, and in solution as an anti-ferment. It is also given in doses of from 10 to 30 grains. 2 957- Sodii Sulphocarbolas. Sulphocarbolate of Sodium. NaC 6 H 5 S0 4 .2H 2 0. This may be prepared by mixing equal parts by weight of C. P. Sulphuric Acid and pure Carbolic Acid. The mixture must then be heated to a temperature of 55° C. (155 F.) for several days, and after that 20 parts of water added. Two parts of Carbonate of Barium are then mixed, a little at a time, with the solution to remove excess of Acid. The solu- tion is then filtered and the Sulphocarbolate of Barium re- maining in solution is decomposed by adding Carbonate of Sodium as long as a precipitate is formed. The liquid is then filtered, concentrated and crystallized. Uses. — This is given as an antiferment in doses of 10 to 20 grains, and is used in cleansing injections. Also for making some preparations. 2958. Sodii Valerianas. Br. Valerianate of Sodium. NaC 5 N 9 2 . The Br. P. directs this to be made as follows : Amylic Alcohol (Fusel Oil), ... 4 fl. ounces. Bichromate of Potassium 9 ounces av. Sulphuric Acid G 1 /? fl. ounces. Solution of Soda, a sufficiency. Water, 72 fl. ounces. Dilute the Sulphuric Acid with 10 fl. ounces of the Water, and dissolve the Bichromate of Potassium in the remainder of the Water with the aid of heat. When both liquids are cold mix them with the Amylic Alcohol in a retort or flask, with SODIUM OR NATRIUM. 757 occasional brisk agitation, until the temperature of the mixture has fallen to about 90 F. (32°2C). Connect with a condenser and distill until about 5 pints of liquid have passed. Saturate the distilled liquid accurately with the solution of Soda, remove any oily fluid that floats on the surface, evaporate till watery vapor ceases to escape, then raise the heats cautiously so as to liquefy the salt. When cold put at once into stoppered bottles. Uses. — This salt is used for making Valerianate of Zinc and other valerianates, and is given as a nervine in doses of 1 to 5 grains. Other Sodium Salts. The foregoing are all the salts of Sodium official in the leading pharmacopoeias, but some other salts are known and have their uses in pharmacy and medicine. The following are the most important : 2959. Carbolate of Sodium— NaC 6 H 5 0. — Made by adding metallic Sodium to Carbolic Acid and allowing the solution to crystallize. 2960. Citrate of Sodium.— By saturating a solution of Citric Acid with Bicarbonate of Sodium, concentrating the solution and crystallizing. 2961. Ethylate of Sodium. — This salt may be prepared the same as Ethylate of Potassium by heating together Acetate of Ethyl and Metallic Sodium. It is used as a caustic. 2962. Lactate of Sodium.— This may be made by diluting Lactic Acid with 3 parts of Water and saturating, while boiling, with Bicarbonate of Sodium, then evaporating. 2963. Nitrate of Sodium— NaN0 2 . — This salt may be prepared by heat- ing together in a crucible 7 parts of Nitrate of Sodium and 1 part of Starch, dissolving the residue in Water and evaporating. 2964. Silicate of Sodium— Na g 9i0 8 . — By mixing 1 part of Silica with 2 parts of dried Carbonate of Sodium, and fusing in an earthenware crucible, and dissolving the mass, when cool and in powder, in water, then filtering, concentrating and • crystallizing. The solution of this salt is known as Water-Glass. (See 1919.) 2965. Tartrate of Sodium— Na 2 C 4 H.,O .2H 2 O. — By dissolving 12 parts of Tartaric Acid and 1 5 pans Bicarbonate of Sodium, each separately in suf- ficient Water, mixing the solutions, filtering, concentrating and crystallizing. Some other Salts of Sodium are used for various purposes, as, Aluminiate of Sodium, and Stannate of Sodium as mordants for dyeing, and many double Salts of Sodium are known but are little used in pharmacy. 758 SPECIES — TEAS. SPECIES — TEAS. Under this heading the German and some other pharma- copoeias direct a variety of mixtures of cut drugs, such as herbs, flowers, barks, roots, woods, leaves, etc., which are designed to be steeped in Water, and the liquid given as a drink or used dry as pillows, or moistened as cataplasms, etc. Several similar preparations have been put upon the market as proprietary remedies and have been quite popular. The following are official in the German Pharmacopoeia ; others will be found among The Standard Remedies. 2966. Species Aromaticae. Aromatic Species or Herbs — Gewurzhafte Krduter. Peppermint, Wild Thyme, Garden Thyme, Lavender Flowers, each 2 ounces or parts, Cloves, Cubebs, each 1 ounce or part. Cut and mix them. This is used dry for filling pillows and scent bags, or may be steeped if desired. 2967. Species Emollientes. Emollient Cataplasm — Eriveichende Krduter. Althaea Leaves, Mallow Leaves, Melilot, Matricaria, Flaxseed, each equal parts. This is made into a poultice for pains, sores, swellings, etc. 2968. Species Laxantes. Laxative Tea — St. Germain Tea — Abfiihrender Thee. Senna 16 parts, Elder Flowers 10 parts, Fennel 5 parts, Anise 5 parts, Bitartrate of Potassium 4 parts. Moisten the Senna previously cut ; sprinkle it uniformly with the Bitartrate of Potassium and mix. When dry, add the other ingredients and mix them well together. 2969. Species Lignorum. Wood Tea — Hohthee. Guaiacum Wood 5 parts, Rest-harrow Root 3 parts, Russian Liquorice Root, Sassafras Wood, each 1 part. Cut them and mix well together. SPIRITUS — SPIRITS. 759 2970. Species Pectorales. Pectoral Tea — Brustthee. Althaea (Flowers), 8 parts. Russian Liquorice Root 3 parts. Orris Root, r part. Coltsfoot, 4 parts. Mullein Flowers, 2 parts, Anise , 2 parts. Cut and mix them. This is the most popular of the teas, being much used by the Germans for colds, influenzas and similar indispositions. A cup of boiling water is poured upon a tablespoonful of the tea and the infusion drank while warm, SPIRITUS — SPIRITS. As understood in Pharmacy, Spirits are solutions of volatile substances in alcoholic or hydro-alcoholic liquids made by dis- tillation. They include solutions of volatile oils, ethers, gases and other substances. Commercially, spirits are understood to be alcohol, or alcoholic liquids, made by distillation and known as Liquors, or Spiritous Liquors. Many liquids are familiarly known as " Spirits " that are classed in pharmacy under other headings, and many of the liquids included among the Spirits, in pharmacy, are familiarly known as essences, extracts, etc. The following are the Spirits official in the leading pharma- copoeias : 2971. Spiritus ^Etheris. Spirit of Ether. The U. S. preparation is made by mixing Stronger Ether, .... 30 parts or 4 fl. ounces. Alcohol 70 parts or SPIRITUS — SPIRITS. The German Pharmacopoeia directs : Ether, by weight, I part. Alcohol, by weight, 3 parts. and is familiarly known as " Hoffmann's Tropfen," although it differs from the U. S. preparation by this name. It is used as an anodyne in doses of 20 to 60 minims. 2972. Spiritus ^theris Compositus. Compound Spirit of Ether — Hoffmann s Anodyne. The U. S. formula is : Stronger Ether, .... 30 parts or 4 fl. ounces. Alcohol, 67 parts or 8 fl. ounces. Etherial Oil, 3 parts or 150 minims. Mix them. The Br. formula amounts to the same, the Etherial Oil being directed to be made in the formula as it is not official in the Br. P. This is used as an anodyne and hypnotic, being generally called for as Hoffmann's Anodyne. The dose is from 20 to 60 minims. 2 973- Spiritus Athens Nitrosi. Sweet Spirit of Nitre — Spirit of Nitrous EtJier. The U. S. formula is: Nitric Acid, 9 parts or 9 ounces av. Sulphuric Acid, 7 parts or 7 ounces av. Alcohol, . . I -rv 4--H j \\i «. f each a sufficient quantity. Distilled Water, \ H y Add the Sulphuric Acid gradually to 31 parts or 36 fl. ounces of Alcohol. When the mixture has cooled transfer it to a tubulated retort connected with a well-cooled condenser, to which a receiver, surrounded by broken ice, is connected air- tight, and which is further connected, by means of a glass tube, with a small vial containing water, the end of the tube dipping into the latter. Now add the Nitric Acid to the con- tents of the retort, and, having introduced a thermometer SPIRITUS — SPIRITS. 761 through the tubulature, heat rapidly, by means of a water- bath, until strong reaction occurs and the temperature reaches 8o° C. (176 F.). Continue the distillation at that temperature, and not exceeding 82 C. (1S0 F.), until the reaction ceases. Disconnect the receiver and immediately pour the distillate into a flask containing 16 parts, or 1 pint of ice-cold distilled water. Close the flask and agitate the contents repeatedly, keeping down the temperature by immersing the flask occa- sionally in ice-water. Then separate the etherial layer and mix it immediately with nineteen times its weight of Alcohol. The processes and formulas of the Br., German and other pharmacopoeias differ considerably from the foregoing, but the resultant preparation is about the same. The liquid separated from the surface of the water before mixing with Alcohol is Nitrous Ether, which has lately had a large sale as concentrated Nitrous Ether, used for making Spirit of Nitre, by mixing with 19 parts of Alcohol. Uses. — Spirit of Nitrous Ether is much used as a diuretic and diaphoretic combined with other remedies. The dose is from 20 drops to a teaspoonful or more. 2974. Spiritus Ammoniae. U. S. Spirit of Ammonia. Stronger Water of Ammonia, .... 8 fl. ounces. Alcohol, recently distilled, and which has been kept in glass, a quantity sufficient to make 16 fl. ounces. Pour the Stronger Water of Ammonia into a flask connected with a well-cooled receiver into which a pint of Alcohol has been introduced. Heat the flask carefully and very gradually to a temperature not exceeding 6o° C. (140 F.), and maintain it at that temperature for about 10 minutes; then disconnect the receiver and having ascertained the ammoniacal strength of tin contents, bymeans of the volumetric solution of Oxalic Acid, add enough alcohol to make the product contain 10 per cent, of Ammonia. Uses. — This is used as a stimulant ^\\^\ antiacid, but is not known to possess any advantage over Water of Ammonia. 762 SPIRITUS — SPIRITS. 2 975- Spiritus Ammoniae Aromaticus. Aromatic Spirit of Ammonia. The U. S. formula is: Carbonate of Ammonium, . 40 parts or 516 grains. Water of Ammonia, . . 100 parts or 3 fl. ounces. Oil of Lemon, 12 parts or 3 fl. drachms. Oil of Lavender Flowers, 1 part or 15 minims. Oil of Pimenta, 1 part or 15 minims. Alcohol, recently distilled, . 700 parts or 24}^ fl. ounces. Distilled water to make, . . 1000 parts or 35 fl. ounces. To the Water of Ammonia contained in a flask add 140 parts, or 4 fl. ounces of distilled water, and afterwards the Car- bonate of Ammonia reduced to a moderately fine powder- close the flask and agitate the contents until the Carbonate is dissolved ; weigh the Alcohol in a tared flask of suitable capac- ity, or pour 400 parts or 24^ fl. ounces in a bottle; add the oils and afterward enough Distilled Water to make the product weigh 1000 parts, or measure 35 fl. ounces; lastly, filter through paper and keep in well-covered bottles. The Br. P. directs this to be made by distillation of the oils with rectified Spirit and Water, and then adding the Carbon- ate and Solution of Ammonia. The formula is as follows : Carbonate of Ammonium, .... 4 ounces av. Strong Solution of Ammonia, ... 8 fl. ounces. Volatile Oil of Nutmeg, \y 2 fl. drachms. Oil of Lemon, 6% fl. drachms. Rectified Spirit, sp. gr. 0.838, . . 1 153^ fl. ounces or 6 pints, Imp. Water, 57/4 fl. ounces or 3 pints. Imp. Place the Oils of Lemon and Nutmeg and Rectified Spirit with the Water in a retort. Distill 7 Imperial pints (134^ fl. ounces), and then distill and separately collect an additional 9 fl. ounces. Place the 9 ounces of distillate, together with the Carbonate of Ammonium and the Strong Solution of Ammo- nia, in a bottle holding rather more than a pint (20 fl. ounces). Securely cork the bottle and gently warm it in a water-bath to SPIRITUS — SPIRITS. 763 140 F. (6o° C), shaking it from time to time until all the salt has dissolved. Filter if necessary, when cold, through cotton- wool, and gradually mix with it the 7 pints (134^ fl. ounces) of the Distilled Spirit. The product should measure an Imperial gallon (153^3 American fl. ounces). Anisated Spirit of Ammonia is made with Rectified Spirit 12 fl.ounces, Oil of Aniseed 3 fl. drachms, Water of Ammonia 3 fl.ounces. The Oil is dissolved in the Rectified Spirit and the Ammonia added. Uses. — Aromatic Spirit of Ammonia is used as a quick stimulant and diaphoretic in doses of 20 to 60 minims. 2976. Spiritus Ammoniae Foetidus. Br. Fetid Spirit of Ammonia. Asafetida, i^s ounces av. Strong Solution of Ammonia, ... 2 fl.ounces. Rectified Spirit, a sufficiency. Break the Asafetida into small pieces and macerate it in a closed vessel in 15 fl.ounces of the Spirit for 24 hours; then distill off the Spirit, mix the product with the Solution of Ammonia, and add sufficient Spirit to make 20 fl.ounces. Uses. — This is given as an antispasmodic and stimulant in doses of 20 to 60 minims. 2977. Spiritus Angelicae Compositus. G. P. ('(impound Sfdrit of Angelica. This is made by macerating Angelica Root 16 parts. Vale- rian | parts, Juniper Berries 5 parts, cut and bruised, in Alcohol 75 parts, Water [25 parts, for 24 hours, then distilling off IOO partsand dissolving in the distillate Camphor 2 parts. Uses. — This is an aromatic stimulant and may be given in doses of !_• to i teaspoonful or more. 764 SPIRITUS — SPIRITS. 2978. Spiritus Anisi. U. S. Spirit of Anise. Oil of Anise 10 parts or 1 ^ fl.ounces. Alcohol, 90 parts or 14% fl. ounces. Mix them. Uses. — This is familiarly known as Essence of Anise, and is considerably used as an addition to carminative mixtures, as an aromatic. The dose is 5 to 20 minims or more. (See 890.) 2979. Spiritus Armoraciae Compositus. Br. Compound Spirit of Horse Radish. Horse Radish Root scraped, . . 20 ounces av. Bitter Orange Peel cut and bruised, 20 ounces av. Nutmeg, bruised, Yz ounce av. Proof Spirit, 1 53 A. ounces. Water, 58 fl. ounces. Mix them and distill a gallon. This is used as an aromatic stomachic, in doses of 1 to 2 fl. drachms. 2980. Spiritus Aurantii. U. S. Spirit of Orange. Oil of Orange Peel, . . 6 parts or i}£ fl.ounces. Alcohol, 94 parts or 14^ fl.ounces. Mix them. This is used as a flavoring for elixirs, syrups, mixtures, etc. (See 509, 91 5.) 2981. Spiritus Cajuputi. Br. Spirit of Cajnput. Oil of Cajuput, 1 fl.ounce. Rectified Spirit, 49 fl.ounces. Mix them. This is given as a stimulant, etc., in doses of ^ to 1 teaspoonful. SPIRITUS — SPIRITS. 765 2982. Spiritus Camphorae. Spirit of Camphor. The U. S. formula for this spirit was changed in the 1880 pharmacopoeia, the new preparation having proven generally unsatisfactory. The 1870 and 1880 formulas are, therefore, both given, the former being preferred. 1870. 1880. Camphor, . . 4^ ounces aw Camphor, . . . 3^ ounces av. Alcohol, ... 2 pints. Alcohol, . . . 1b 1 /, fl.ounces. _. , , „ . . , . . Water 9 fl.ounces. Dissolve the Camphor in the Alco- hol and filter through paper. Dissolve the Camphor in the Alco- hol, add the Water and filter through paper. The Br. P. formula is : Camphor, . . 1 ounce av. Rectified Spirit, 9 fl.ounces. The G. P. formula is : Camphor, 1 part. Alcohol, 7 parts. Water, 2 parts. Uses. — Spirit of Camphor is used extensively in liniments and other similar preparations in which it is obvious that the addition of Water in the formula is inexpedient. In medicine it is used for pain, swellings, rheumatic affections and in fact for nearly everything both externally and internally. The dose is 10 to 30 minims. 2983. Spiritus Chloroformi. Spirit of Chloroform. The U. S. formula is : Purified Chloroform, . . 10 parts or 623 grains. Alcohol 90 parts or 15 fl.ounces. It may be made with Chloroform 1 fl.ounce, Alcohol 16 fl.ounces. 766 SPIRITUS — SPIRITS. The Br. formula is : Chloroform, I fl. ounce. Rectified Spirit, 19 fl. ounces. Uses. — Spirit of Chloroform is often prescribed and dis- pensed as Chloric Ether. It is used externally and internally as an anodyne and relaxative. The dose is 20 to 60 minims. 2984. Spiritus Cinnamomi. Spirit of Cinnamon. The U. S. formula is: Oil of Cinnamon, ... 10 parts or 1^ fl. ounces. Alcohol, 90 parts or 14^3 fl. ounces. Mix them. The Br. P. formula is : Oil of Cinnamon, 1 fl. ounce. Rectified Spirit, 49 fl. ounces. Uses. — Spirit of Cinnamon is used as a flavoring ingredient for many preparations, and is given as a quick stimulant in doses of 20 to 60 minims. It is familiarly known as Essence of Cinnamon. (See 897.) 2985. Spiritus Cochleariae. G. P. Spirit of Scurvy Grass. Scurvy-Grass 8 parts. Alcohol, 3 parts. Water, 3 parts. Cut the fresh flowering Scurvy-grass, mix it with the Alco- hol and Water, and distill off 4 parts. This is similar to but less aromatic than the Br. Spiritus Armoraciae Compositus. The dose is 1 to 2 fl. drachms. 2986. Spiritus Formicarum. G. P. Spirit of Formic Acid. Alcohol, 70 parts. Water, 26 parts. Formic Acid, 4 parts. Mix them. This is also called Spirit of Ants. SPIRITUS — SPIRITS. 767 2987. Spiritus Frumenti. Whisky. This is official in the U. S. P., and is described as an Alco- holic liquid, obtained by the distillation of fermented grain (usually corn, wheat or rye), and at least two years old. Whisky contains about 50 per cent, of Alcohol, its standard proof being 100. The method of preparing it is described under the heading SPIRITOUS LIQUORS. It is a diffusive stimulant. 2988. Spiritus Gaultheriae. U. S. Spirit of Gaultheria. Oil of Gaultheria (Wintergreen), 3 parts or 165 minims. Alcohol, 97 parts or 1 pint. Mix them. This is a weak solution of the oil corresponding with the strength of similar British Spirits. To make Essence of Win- tergreen, 1 ounce of the Oil should be dissolved in 15 fl. ounces of Alcohol. (See 927.) 2989. Spiritus Juniperi. Spirit of Juniper. The U. S. formula is : Oil of Juniper 3 parts or 224 minims. Alcohol 97 parts or 1 pint. Mix them. (See also 90S.) The liquor called gin is often prescribed under the name Spiritus Juniperi, but is entirely unlike this preparation. The Br. formula directs Oil of Juniper 1 part, Alcohol 49 parts. The G. P. directs Juniper Berries 4 parts, Alcohol, Water, each 15 parts, allowed to macerate: for 24 hours, and then 20 parts to be distilled. Uses. — Spirit of Juniper is used as a stimulating diuretic, and for mixtures. 768 SPIRITUS — SPIRITS. 2990. Spiritus Juniperi Compositus. U. S. Compound Spirit of Juniper. Oil of Juniper, .... 10 parts or 27 minims. Oil of Caraway, .... 1 part or 3 minims. Oil of Fennel, .... 1 part or 3 minims. Alcohol 3000 parts or 20 fl. ounces. Water, sufficientto make 5000 parts or 2 pints. Dissolve the Oils in the Alcohol, add the Water, mix and filter. This is given as a stimulant and diuretic. 2991. Spiritus Lavandulae. Spirit of Lavender. The U. S. formula is : Oil of Lavender Flowers, . 3 parts or 220 minims. Alcohol, 97 parts or 16 fl. ounces. (See also 909). The Br. P. formula directs I fl. ounce of Oil of Lavender to be dissolved in 49 parts of Rectified Spirit. The G. P. directs Lavender Flowers, 5 parts to be mace- rated in Alcohol 15 parts, Water 15 parts, for 24 hours, and then 20 parts distilled. Uses. — Spirit of Lavender is given as an aromatic stimulant and stomachic in doses of 20 to 60 minims. 2992. Spiritus Limonis. U. S. Spirit of Lemon. Oil of Lemon, 6 parts or 1 fl. ounce. Lemon Peel, freshly grated, . 4 parts or ]/ 2 ounce. Alcohol, sufficient to make 100 parts or 1 pint. Mix, macerate and filter. This is also known as Essence of Lemon or Flavoring Ex- tract of Lemon. It is used for flavoring medicinal prepara- tions, syrups, pastry, etc. (See also 910.) SPIRITUS — SPIRITS. 2993. Spiritus Melissae Compositus. G. P. Compotind Spirit of Balm. Balm Leaves 14 parts, Lemon Peel 12 parts, Nutmeg 6 parts, Cinnamon, Cloves, each 3 parts, are bruised and distilled with Water 250 parts, Alcohol 150 parts, recovering of the distillate 200 parts. This is a fragrant spirit used for flavoring medicines, etc. 2994. Spiritus Menthae Piperitae. Spirit of Peppermint — Essence of Peppermint. The U. S. formula is: Oil of Peppermint, .... 10 parts or \T>/% fl. ounces. Peppermint in coarse powder, 1 part or 60 grains. Alcohol, sufficient to make . 100 parts or 1 pint. The substances are mixed, macerated and filtered. By add- ing a little Carbonate of Magnesium to the filter a clearer preparation is produced. The Br. P. directs 1 fl. ounce of Oil of Peppermint to be dissolved in 49 fl. ounces of Rectified Spirit. The G. P. formula is 1 part of Oil of Peppermint dissolved in 9 parts of Alcohol. Essence of Peppermint is usually made with Oil of Pepper- mint 1 ounce, Alcohol 15 ounces. (See 918.) Uses. — This essence is extensively used as household remedy for flatulence, colic, etc. The dose is 10 to 60 drops. 2995. Spiritus Menthae Viridis. U. S. Spirit of Sjuarmint — Essence of Spearmint. Oil of Spearmint, .... 10 parts or i/s fl. ounces.. armint in coarse powder, 1 part or 60 grains. Alcohol, sufficient to make . 100 parts or 1 pint. Mix, macerate and filter. (See also 925.) Uses. — This is used for similar purposes as Essence oi Pep- permint. 770 SPIRITUS — SPIRITS. 2996. Spiritus Myrciae. U. S. Spirit of Myrcia — Bay Rum. Oil of Myrcia, .... 16 parts or 1 fl. ounce. 1 part or 35 minims. Oil of Orange Peel, Oil of Pimenta, . Alcohol, . . . Water, .... To make . . . 1 part or 28 minims. IOOO parts or 78 fl. ounces. 782 parts or 49 fl. ounces. 1800 parts or 1 gallon. Mix the Oils with the Alcohol and gradually add the Water to the solution. Set the mixture aside in a well-stopped bottle for 8 days, then filter through paper in a well-wetted funnel. Other formulas for Bay Rum which may be preferred to this will be found among the toilet preparations. 2997. Spiritus Myristicae. Spirit of Nutmeg — Essence of Nutmeg. The U. S. formula is : Oil of Nutmeg, 3 parts or 220 minims. Alcohol, 97 parts or 1 pint. Dissolve the Oil in the Alcohol. The Br. formula is Volatile Oil of Nutmeg 1 fl. ounce, Rec- tified Spirit, 49 fl. ounces. This is used as a flavoring for medicinal preparations and pastry. (See 914.) 2998. Spiritus Odoratus. Perfumed Spirit — Cologne Water. Oil of Bergamot, ... 16 parts or 2 fl. ounces. Oil of Lemon, .... 8 parts or 1 fl. ounce. Oil of Rosmary, .... 8 parts or 1 fl. ounce. Oil of Lavender Flowers, . 4 parts or y 2 fl. ounce. Oil of Orange Flowers (Neroli), 4 parts or ]/ 2 fl. ounce. Acetic Ether, .... 2 parts or ^ fl. ounce. Alcohol, 800 parts or 106 fl. ounces. Water, 158 parts or 17 fl. ounces. To make 1000 parts or 1 gallon. SPIRITUS — SPIRITS. 771 Dissolve the Oils and the Ether in the Alcohol and add the Water. Set the mixture aside in a well-closed bottle for eight days, then filter through paper in a well-covered funnel. Other formulas for Cologne which may be preferred to this will be found among the perfumes and toilet preparations. 2999. Spiritus Rosmarini. Br. Oil of Rosmary, 1 fl. ounce. Rectified Spirit, 49 fi. ounces. Dissolve. An aromatic stimulant. Dose 20 to 60 minims. 3000. Spiritus Saponis. G. P. Spirit of Soap. Olive Oil, 60 parts. Solution of Potassa, G. P., 70 parts. Alcohol, 300 parts. Water, 170 parts. Boil the Oil and Solution of Potassa with one-fourth of the Alcohol on a water-bath until the Oil is saponified, and a small portion is found on trial to form a clear mixture with Alcohol and Water. Now replace any Alcohol lost by evaporation, add the remaining three-fourths of the Alcohol and the Water, and filter the liquid when cold. 3001. Spiritus Sinapis. G. P. Spirit of Mustard. Volatile Oil of Mustard, 1 part. Alcohol, 49 parts. Mix and dissolve. A rubefacient and quick stimulant. It is given in doses of 10 to 60 minims. 3002. Spiritus Vini Gallaci. Brandy — ■ French Brandy. An Alcoholic liquid obtained by the distillation of fermented grapes, and al leasl four years old. It is I'm ther noticed under the heading Spiri n »US LIQUORS. The German- Latin title is Spiritus Vini Cognac. 77*2 SPIRITUS — SPIRITS. Other Spirits. Besides the official Spirits named, Alcohol, Diluted Alcohol, Rectified Spirit, and proof Spirit are noted under the heading ALCOHOL. The Alcoolats of French Pharmacy which corre- spond with spirits are noticed pages 94 and 453. Many of the preparations used in perfumes, and also Spiritous Liquors are classed as Spirits. A few only of those most popular in medi- cine, which have not been mentioned, are noticed here. 3003. Spirit of Bryony Compound. — Bryony 8 ounces, Valerian 2 ounces, Pennyroyal 3 ounces, Rue 3 ounces, Mugwort, Feverfew, Savin, each yi ounce, Orange Peel, Lovage seeds, each 1 ounce, Brandy 10 pints, macerate and distill. 3004. Spirit Fioravanti. — Swiss Turpentine 5 ounces, Elemi, Tacama- haca, Amber, Liquid Styrax, Galbanum, Myrrh, Bayberries, each 1 ounce, Aloes, Galangal Root, Ginger, Zedoary, Cinnamon, Cloves, Nutmeg, Cretum marium leaves, each ]/ 2 ounce, Alcohol 2 pints, macerate 6 days and distill 25 fl.ounces. This is also known as Balsam Fioravanti, and is used for bruises, " black and blue " spots, etc. 3005. Spirit of Mastic Compound. — Mastic, Myrrh, Olibanum, each 1 ounce, Rectified Spirit 20 ounces, macerate and distill. This is used as an application for bruises, lameness, etc. 3006. Spirit of Honey Compound.— Honey 32 parts, Coriander 32 parts, Lemon Peel, fresh, 4 parts, Cloves 3 parts, Nutmeg, Benzoin, Storax, each 2 parts, Vanilla 1 part, Rose Water 20 parts, Orange Flower Water 20 parts, Alcohol 200 parts, macerate for 3 days and distill all the spiritous part. This is a fine aromatic for adding to other preparations or the toilet. 3007. Vulnerary Spirit. — Dried Sage, Wormwood, Fennel Hyssop, Mar- joram, Savory, Thyme, Rosmary, Calamint, Balm, Peppermint, Scordium, Fresh leaves of Angelica, Basil, and Lavender Flowers, each 2 ounces, Proof Spirit 10 pints, digest 14 days and distill over 7 pints. This is a stimulant and vulnerary much used on the Continent as a cordial and cosmetic. 3008. Spirit Pyoracetic, Acetone. — C 3 H 6 0. This is an inflammable volatile liquid obtained by subjecting Acetate of Lead or other mineral ace- tates to dry distillation. The acetates are first dried to make them anhydrous and then distilled with increased heat until all the volatile portions have passed over. The receiver contains crude acetone, which is purified by vari- ous means. It is also obtained as by-product in the manufacture of Aniline and some other substances. It is a solvent for resins and oils. 3009. Spirit Pyroxylic — Wood Naphtha— Wood Spirit. — This is another name for Methylic Alcohol, which is obtained from crude Pyroligne- ous Acid by distillation and subsequent treatment. It was once employed considerably in medicine under the name of Hasting 's Wood Naphtha. (See also page 95.) STANNUM — TIN. 773 STANNUM- TIN. Symbol, Sn ; Atomic weight, 1 1 7.7 ; Sp. gr. 7.30. This is a metallic element known since the earliest civiliza- tion. It is found mostly in the form of ore associated with other metals, and is obtained generally by smelting, and cast in bars or made into grain tin. It is white, like silver, harder than lead, very malleable, melts at 442 F., and is volatilized at a white heat. Tin is extensively used in the arts in making tin plate, tin foil, solder, etc. In solution with acids it is used as a mordant for dyeing, and its salts are somewhat used for various purposes. It forms important alloys with many other metals, making- bronze, bell metal, solder, pewter, etc. In the form of Tin Foil it is used to quite an extent for wrapping packages to keep them from moisture and to protect them, etc. It is also used for making tubes for paints, oint- ments, etc. The following are the Salts of Tin most used : 3010. Chlorides of Tin — Stannous Chloride. Sn CL. — An anhydrous salt is made by distilling together a mixture of Tin and Chloride of Mercury. A hydrated or crystallized salt is made by boiling Tin in excess with Hydro- chloric Acid, the liquid may be poured off and evaporated to a granular salt. Stannic Chloride, SnCl 4 . This is made by dissolving grain tin in a mix- ture of 2 measures of Hydrochloric Acid with one measure each of Nitric Acid and Water. The solution evaporated to granulation is known as " Salts of Tin," used for dyeing. Solution of Chloride of Tin (Stannic Chloride) is also much used for dyeing. (See 2042.) This is also known as Spirits of Tin. 301 1. Hydrates of Tin — Hydrated Oxide of Tin, Sn(HO) 3 .— This is made by precipitating Stannous Chloride with Carbonate of Potassium, and washing the precipitate. Hydrated Peroxide of Tin or Stannic Acid, Sn(HO) 4 is made by adding Carbonate of Potassium to a solution of Stannic Chloride, and washing the precipitate. 3012. Iodides of Tin — Protiodide of Tin, SnP, — is prepared by heating tin and iodine together. Stannic Iodide Snl, is made by dissolving tin in hydriodic acid and crystallizing. 3013. Oxides of Tin — Stannous Oxide, SnO, — is made by igniting the Hydrate of Tin in an atmosphere of Carbonic Anhydride. Stannic Oxide is prepared by the action of Nitric Acid on metallic tin and washing the powder 774 STRONTIUM. with water. It is also prepared by heating tin above its melting point in the air. It is known as Polisher's Putty, and is used for polishing tin ware and other substances. 3014. Sulphides of Tin— Stannous Sulphide, SnS— is made by heating tin and sulphur together. Stannic Sulphide SnS 2 , known also as bronze powder, mosaic gold, etc., is made by melting tin 12 ounces, and adding Mercury 6 ounces, allow to cool and add Chloride of Ammonium 6 ounces, Sulphur 7 ounces, and after thoroughly mixing heating in a glass flask by a sand-bath for several hours to redness until white fumes cease to rise. This is used as a substitute for gold in bronzes, varnishes, sealing wax, etc. 3015. Tin Mordants— A great variety of these are used for dyeing, different combinations being used for different purposes. For Cochineal, a mixture of Nitric Acid and Water, each 2 pounds, Sal Ammoniac 2 ounces, dissolved, and \yi ounces of pure Tin, gradually dissolved in the liquid. For Madder — Nitric Acid 8 parts, Common Salt 1 part, Water 8 parts. Tin 1 part. This is the common Tin Spirit used by dyers. Other combinations are used for other purposes. STRONTIUM. Symbol, Sr. ; Atomic weight, 87.4. A metallic element discovered by Sir H. Davy in 1808, and similar in its characteristics to Barium, but having less metallic luster. Its salts are chiefly used in pyrotechnics for making red fire, but are not employed in medicine. 3016. Carbonate of Strontium — SrC0 3 . — This may be prepared by add- ing a solution of Carbonate of Sodium to a solution of Nitrate of Strontium and collecting the precipitate. 3017. Nitrate of Strontium — Sr2N0 3 . — This is made by saturating Nitric Acid with Carbonate of Strontium, concentrating the solution and crystallizing or stirring while evaporating to granulate. It must be dried by very gentle heat. It is used in making red lire for pyrotechnics and theatrical illuminations. 3018. Strontium Oxide — SrO. — This is obtained by igniting the Nitrate of Strontium and collecting the residue. 3019. Strontium Sulphate — SrS0 4 . — This may be made by adding Sulphuric Acid to a solution of Nitrate of Strontium ; Sulphate of Strontium is precipitated. SUCCI — JUICES. 775 SUCCI — JUICES. The name juice is applied in pharmacy to a variety of very different preparations. No juices as such are now official in the U. S. P., but the Br., French and German Pharmacopoeias recognize several inspissated and liquid juices. Besides the juices that are employed as medicinal agents, the juices of fruits are extensively used in making syrups for Soda Water and other purposes. The following are the juices which may be classed as medicinal. 3020. Succus Belladonnae. Br. Juice of Belladonna. Fresh leaves and young- branches of Belladonna, . . 7 pounds av. Rectified Spirit a sufficiency. Bruise the Belladonna in a stone mortar, press out the juice, and to every 3 measures of juice add one of the Spirit. Set aside for seven days and filter, keep in a cool place. The dose is 5 to 15 minims. 3021. Succus Conii. Br. Juice of Hemlock. Fresh leaves and young branches of Hemlock (Conium), 7 pounds. Rectified Spirit, a sufficiency. Make in the same manner as the preceding. The dose is )/ z to 1 fl. drachm. 3022. Succus Hyoscyami. Br. Juice of Henba?ie. Fresh leaves, flowering tops and young branches of Henbane, 7 pounds. Rectified Spirit, a sufficiency. Make in the same manner as Juice of Belladonna. Dose yi to 1 fl. drachm. 3023. Succus Juniperi Inspissatus. G. P. Inspissated Juice of Juniper Berries — Extract of J 101 /per Berries. Fresh Juniper Berries bruised 1 part. Hot Water 4 parts. Pour the Water on the Berries and having stirred them frequently during 12 hours, express the liquid and evaporate the strained liquid to a thin 776 succi — juices. 3024. Succus Liquiritiae. G. P. Extract of Liquorice. An Extract prepared by boiling and expressing the roots of glycyrrhiza glabra. The ordinary Extract of Liquorice of commerce. It is made up in the form of mass for manufacturing purposes, but is made into sticks for sale and use in pharmacy. The Liquorice Mass is extensively used in making plug tobacco. 3025. Succus Liquiritise Depuratus. G. P. Purified Extract of Liquorice. Prepared by exhausting the Extract of Liquorice with cold water and evaporating the clear liquid to a thick extract. (See also 1026.) 3026. Succus Scoparii. Br. Juice of Broom. Fresh Broom Tops, 7 pounds. Rectified Spirit, a sufficiency. Make in the same manner as Juice of Belladonna. Dose 1 to 2 fl.drachms. 3027. Succus Taraxaci. Br. Juice of Dandelion. Fresh Dandelion Root 7 pounds. Rectified Spirit, a sufficiency. Make in the same manner as Juice of Belladonna. Dose 1 to 2 fl.drachms. Chicory Jtiice is made in the same manner. In French Pharmacy the juices of a great number of plants prepared in a similar manner to the foregoing are used. Fruit Juices. Although these are not employed in medicine, except for their flavoring and acid constituents, they are extensively used by druggists for making Soda Water Syrups and aerated beverages. The following general process for preparing Fruit Juices if carefully followed will prove perfectly satisfactory : 3028. General Process for making Fruit Juices. The fruit should be thoroughly ripe, but not over ripe, and it should be carefully selected, throwing out all that is mouldy or spoiled. Some fruits require mashing or grinding and others do not. When the juice can well be obtained without mashing the fruit, as with strawberries, raspberries and succi — juices. 777 similar fruit, it is best not to mash them, as when mashed they form a gelat- inous mass from which it is more difficult to express the juice then when in their natural state. Grapes, cherries, currants and other similar fruit having a heavy skin must be ground or mashed with pounders ; grinding is the best. Pineapples, apples, pears, etc., must be either ground, grated or dessicated. and pulpy fruits like lemon, orange, etc., should be chopped or otherwise cut up so that the juice may be obtained by pressure. When the fruit is prop- erly reduced to the condition for pressing it is put in a wooden press and the juice as much as possible obtained from it by pressure. In making juice in a large way the pulp is run through wooden rollers first, by which a large portion of the juice is separated and the pomace afterward pressed in a press. A layer press is the best, but an ordinary wooden hoop cider press will do for small manufacturing and still smaller quantities may be imperfectly pressed out by hand. In small presses all the juice cannot be obtained with one pressing, and the pumace may be taken out, broken up and pressed again. When the juice is obtained, care being taken to keep it as cool and clean as possible, it may either be put up hot in bottles without any preservative or cold in bulk by adding the proper preserving ingredients. If put up hot, the juice is to be brought to a quick boil and skimmed ; then, while still boiling hot, put into hot bottles taken from boiling water and at once securely corked and put away in a cool place. If put up by the cold process in bulk, it may be preserved by adding 1 5 per cent, of cologne Spirit of Alcohol proof, or by adding to each gallon 30 grains of Salicylic Acid dissolved in 4 ounces of Cologne Spirit, or by dissolving in it all the sugar that will hold in solution. After standing, juices deposit albuminous matter, which may be separated by decanting or filtering. The cold process for preparing juices secures the finest product and the best flavor, much of the fine flavor of fruits being volatilized when heated. The important points to bear in mind are : first, to select good, sound ripe fruit; second, to work it up quickly and keep it cool and as little exposed as possible ; and third, to put up and put away in a cool place before fermenting, or as soon as possible after the juice is obtained. No matter if the juice is " muddy," it will settle clear, and can be decanted or filtered before using. Juices put up by the cold process retain their entire flavor and most of their color ; if heated, much of their flavor is dissipated and the color changed. Fruit Syrups may be made from these juices as a rule, by adding 1 part of the juice to 4 parts of syrup. They are very convenient to use as additions to medicinal preparations and are extensively used as soda water syrups. The following Juices and Syrups may be made in the manner which has been described : Apricot, Currant, Black, ( (range, Quince, Blackberry, Currant, Red, Peach, Raspberry, Black, Blueberry, Grape, Pear, Raspberry, Red, Cherry, Black, Lemon, Pineapple, Strawberry, Cherry, Red, Lime, I'lum or P ruen, and others. 778 SULPHUR. SULPHUR. Symbol, S ; Atomic weight, 32. Sulphur is an elementary substance, existing in nature mostly in combination with other substances in the form of ores, but sometimes found in a free state as a result of vol- canic action. It is closely allied in its analogies and charac- teristics to phosphorus. Its salts, the sulphides and sulphates, are very abundant in all parts of the world, and form an im- portant part of the mineral constituents of the earth. Sulphur is found in three different forms in the market : Sublimed Sulphur, Roll Sulphur, and Precipitated Sulphur, all of them having their uses in the arts and in pharmacy. It combines directly with several of the elements, forming sul- phides or snlphnrcts, which vary in their union with other bodies, some of them acting as bases and some as acids. Sulphur is employed to a large extent for manufacturing sulphuric acid, gunpowder, vulcanized rubber, and many other articles of great commercial importance. 3029. Sulphur Sublimatum. Sublimed Sulphur. S. Sublimed Sulphur, or Flowers of Sulphur, is made by heating Sulphur and conducting the vapor into properly con- structed cooled chambers, where the Sulphur collects on the sides and bottom in the form of a light powder, which is known in commerce as " Sulphur." It is a light-yellow pow- der, insoluble in water or alcohol, and when ignited burning with a blue flame with production of Sulphurous Acid gas. Brimstone or Roll Sulphur is the same chemically, but is run into sticks or rolls, and usually contains impurities. Uses. — Sublimed Sulphur is used in the arts for various purposes, and given in medicine as a laxative and diaphoretic in doses of 20 to 120 grains, or more. It is used externally in the form of ointment as an application for parasitic diseases, etc. SULPHUR. 779 3030. Sulphur Lotum. Washed Sulphur. S. This is a purified Sulphur, made by washing 12 parts or 16 ounces of Sulphur with 1 part or 10 fl. drachms of Water of Ammonia and a quantity of water sufficient, so that the wash- ing will produce no precipitate with test solution, Chloride of Barium, showing it free from soluble combinations or Sul- phuric or Sulphurous Acids. Uses. — This is intended to be used for internal administra- tion, and is frequently mixed with Cream of Tartar and taken as a laxative and blood-cleanser. 3031. Sulphur Praecipitatum Lac Sulphur. Precipitated SiripJmr — Milk of Sulpliur. S. Sublimed Sulphur, .... 100 parts or 2 pounds. Lime, 50 parts or 1 pound. Hydrochloric Acid, ) ■yxj r each a sufficient quantity. Slake the Lime and make it into a uniform mixture with 500 parts or 10 pints of Water; add the Sulphur, previously well dried and sifted, and mix well together; then add 1000 parts or 20 pints of water, and heat the mixture to boiling for one hour, stirring constantly, and adding water occasionally to make up for evaporation ; then cover the vessel, allow to cool, pour off the clear solution and filter the remainder, add- ing the filtrate to the poured off portion, and gradually add to the liquid Hydrochloric Acid diluted with an equal volume of Water until the liquid is nearly neutral but still slightly alkaline. Collect the precipitate which forms on a strainer and wash with water until the washings are tasteless, and dry by gentle heat. Uses. — Precipitated Sulphur is much used in making hair restoratives and general!}' in liquid preparations, when Sul- 780 SULPHUR. phur is required to be suspended, as it is much finer and softer than other forms of Sulphur. It is also used in making oint- ments, cerates, etc. The dose is from 30 grains to 3 drachms. 3032. Sulphuris Iodidum. Iodide of Sulphur. Washed Sulphur, I part or 1 ounce. Iodine, 4 parts or 4 ounces. Rub them together until they are thoroughly mixed, then introduce the mixture into a flask, close the orifice loosely, and apply a gentle heat, so as to darken the mass without melting it. When the color has become uniformly dark throughout, increase the heat so as to liquefy the mass, and incline the flask in different directions in order to return into the liquid any portion of the Iodine which may have con- densed on the inner surface of the flask; then withdraw the heat, and after the liquid has become solid break the flask and remove the mass to glass-stoppered bottles. Uses. — This compound is chiefly used for making ointment for skin diseases. Other Forms of Sulphur. 3033. Amorphous Sulphur— Sulphur Fitscum, Brown Sulphur, Red Sulphur. — This is prepared from Sublimed Sulphur by melting it, increasing the heat to from 320 to 350 F., and continuing at that temperature for about half an hour, or until it becomes brown and viscid, then pouring into water. In this state it is ductile and easily moulded like wax, but does not become fluid until heated to over 6co° F. 3034. Roll Sulphur or Brimstone. — This is Crude Sulphur purified by melting, skimming and pouring it into moulds. It is used extensively for bleaching, burning more readily than sublimed Sulphur, and as a cement for setting stone and many other purposes. It is seldom employed in medicine because of its impurities. 3035. Sulphur Vivum — Black Sulphur, Crude Sulphur, Horse Brim- stone. — This is Crude native Sulphur, a gray or mouse-colored powder. It is seldom found in the market, — the residuum of the subliming pots being substituted for it. It contains quite a large percentage of Arsenic, and is therefore not used except for horses and stock. SULPHUR. 781 Salts of Sulphur. The Iodide of Sulphur is the only official salt in which sulphur acts as the basic substance. It forms compounds, however, with the other halogen elements. Bromine — Bromide of Sulphur S 2 Br 2 , and with Chlorine — Chloride of Sulphur, S 2 C1 2 , but they are seldom used. With most of the positive elements Sulphur combines, forming Sulphides or Sulphurels, which are noticed under the basic elements with which the combination is made. The name hepar was given by the old chemists to the liver-colored combinations formed by the union of Sulphur with antimony, potassa, soda, calcium, etc. It is still retained in Homoeopathic Pharmacy. Hepar Sulphuris or Hepar Sulphur (Calx Sulphurata), Hepar Sulphuris Kalinum (Sulphuretted Potash), being the official titles in their pharma- copoeia. Acids of Sulphur. Sulphur forms combinations with hydrogen and oxygen, as follows : 3036. Hydrogen Sulphide — Sulphuretted Hydrogen H 2 S. — This is an inflammable gas occurring in nature and produced by the decomposition of substances containing sulphur. It may be conveniently prepared by decom- posing ferrous sulphide with Sulphuric Acid diluted with water. This gas is extensively used in chemical laboratories in the manufacture of chemicals. Hydrogen Persidphide is an oily fluid similar in properties and uses to Hydrogen Peroxide. With Oxygen, Sulphur forms two oxides, which are known as Sulphurous and Sulphuric Anhydrides, and which unite with the elements of water making Sulphurous and Sulphuric Acids. 3037. Sulphurous Acid — H 2 S0 3 . — When Sulphur is burned in the atmos- phere, gaseous Sulphurous Anhydride or Oxide S0 2 is formed, which, when dissolved in water produces Sulphurous Acid. The Sulphurous Acid of the market contains about 5 per cent, or less of the gas. (See page 74.) The salts formed with this acid and basis are called Sulphites. 3038. Sulphuric Acid — H 2 S0 4 — Oil of Vitriol. — This Acid is now mostly made by roasting iron pyrites or Bisulphide of Iron or other Sulphides, the metals of which have a commercial value. The Sulphur contained in the compounds is converted into Sulphuric Acid by distilling its vapor, which consists of Sulphuric anhydride or < >.\ide S( > :; , which unites with the elements of water, forming Sulphuric Acid. This Arid is extensively used in various manufacturing industries and in pharmacy. (See page 73.1 Tin- salts formed with this acid and bases are called Sulphates. Besides these acids formed from the oxides of Sulphur, Hypo-Sulphurous Acid, H 8 S0 9 , the oxide corresponding to which has not been determined, Thiosulphurii Acid, I l.,S,,0 ;i and other Acids, forming a Thionic series, are known. 782 SULPHUR. SUPPOSITORIA — SUPPOSITORIES. 3039. Sulpho-Acids. — Sulphuric Acids unites with some other acids, forming a class of Sulpho-Acids. 3040. Sulpho-Carbolic Acid— HC 6 H 3 S0 4 — is made by mixing equivalent weights of Sulphuric and Carbolic Acids. It is obtained from its solution as a solid by crystallization. This Acid forms with metallic bases a class of salts known as Sit/p/iocarbo/ates, as Sulphocarbolate of Calcium Ca 6 (CH 5 S0 4 ) 2 , Sulphocarbolate of Copper Cu(C 6 H 5 S0 4 ) 2 , Sulphocarbolate of Iron, Fe (C 6 H 5 S0 4 ) 2 , Sulphocarbolate of Sodium, Na(C 6 H 5 )S0 4 , Sulphocarbolate of Potassium, KC 6 H 5 S0 4 , Sulphocarbolate of Ammonium, NH 4 C 6 H 5 S0 4 , Sulphocarbolate of Zinc, Zn(C c H 5 S0 4 ) 2 , etc. 3041. Sulphocyanogen.— This is a compound, made by the union of Sul- phur and Cyanogen, acting as an acid and forming with some bases salts known as Sulphocyanides. 3042. Sulphovinic Acid — C 3 H 5 HS0 4 . — This acid is formed by the union of Sulphuric Acid with the Etheylic Alcohol radical before the forma- tion of ether is completed. The salts of this acid are called Sulpha vinates, or Sulphetliylates, as Sulphethylate of Calcium, copper, potassium, sodium, etc. SUPPOSITORIA — SUPPOSITORIES. Suppositories are bodies, usually of cone shape, and made of some substance readily melted or soluble at the tempera- ture of the internal cavities of the body. They are prepared with medicinal substances mixed with the mass so that their effect will be obtained as the suppository melts. Moulds of suitable form may be obtained for making sup- positories, the ones usually employed beir g cone-shape for making rectal suppositories. Many substances have been employed as a base for supposi- tories, but none has been found so suitable for this purpose as Oil of Theobroma (" Butter of Cacao "). It melts readily at the temperature of the body, yet has consistence enough to retain its form at ordinary temperatures. It is mild, bland, and non-irritant. Many attempts have been made to introduce suppositories in which Gelatin is used as a base; but without success, for the reason that it cannot be made soluble at the normal temperature of the body, and is therefore worthless for this purpose. The following is in substance the general formula for sup- positories given in the 1S80 Pharmacopoeia: SUPPOSITORIA — SUPPOSITORIES. 783 3043. General Formula for Suppositories. Mix the medicinal substance, or substances (previously brought to a proper consistence if necessary), with a small quantity of Oil of Theobroma, by rubbing them together, and add the mixture to the remainder of the Oil of Theobroma, previously melted and cooled to the temperature of 35 C. (95 ° F.). Then mix thoroughly without applying more heat and immediately pour the mixture into suitable moulds, which have been previously cooled on ice. The melted oil, etc., should be stirred before filling each mould. Suppositories may be made without moulds by mixing the medicinal substance, or substances, with a small portion of the Oil of Theobroma in a mortar which has been slightly warmed, and then adding the remainder of the Oil of Theobroma and mixing thoroughly. When thus mixed the mass may be trans- ferred to a pill tile (which has been sprinkled with flour or other convenient substance to prevent it sticking), rolled out and divided the same as a pill mass. The sections may then be made conical in shape by rolling one end of them on the pill tile. This is by far the most convenient way to make supposi- tories when prescribed, and it ensures a more even distribution of the medicinal agent than when made by heat, as it is almost impossible to incorporate many of the solid extracts with the melted oil. The solid Extracts must be softened by rubbing with a little water or alcohol before mixing with the Oil. Several machines for making suppositories by the cold pro- cess have been invented, some of which are very good, though but few druggists have enough demand for suppositories to make it profitable to buy one. The following general formula for making one dozen 15 grains suppositories will be found convenient for reference. 3044. Formula for one dozen Suppositories. The medicinal substance or substances. Oil of Theobroma, sufficient to make . 180 grains. Make as previously directed. 784 SUPPOSITORIA — SUPPOSITORIES. This is the size that is usually prescribed as rectal supposi- tories with which druggists are most familiar. They are usually made conical in form. Vaginal suppositories are usually made at least double this size, and oviform. Urethral Suppositories are generally made "long, slim and slender," like a pipe stem. Pessaries are made larger than any of the preceding, and usually ob-oviform. Suppositories are also made hollow for the introduction of medicine, but are not in general favor, as the prolonged action of the medicine by the gradual, melting of the suppository, is usually desired. A great variety of combinations are made up in the form of Suppositories, being naturally classed according to the uses for which they are designed, as Anodyne, Antiseptic, Astrin- gent, Hypnotic, etc. There are also Rectal, Urethral, Vaginal, Aural, and Nasal Suppositories, made up in different forms to suit the localities in which they are designed to be used. The medicinal composition of the principal Suppositories is shown in the following list, each Suppository containing the stated quantity of the medicinal agent, with sufficient Cacao Butter to make them. Other substances also are used as a base for Suppositories, as Starch Plasma, Soap, etc., but they are not as good as Cacao Butter : Rectal Suppositories. These are generally made in cone-shape moulds, containing about 15 grains. The moulds are dusted with Lycopodium or fine Starch, and cooled on ice before pouring in the material. ANODYNE. 3045. Extract Belladonna. — These 4 grains, Aqueous Extract Opium 1 are made )^, )/ z and 1 grain in each of grain, in each. Extract of Belladonna. ^g H yoscyamus, Codeine, and 3046. Extract Hyoscyamus.— Cannabis Indica.— Extract Hyoscya- These are made to contain 3 or 5 grains mus> Codeine, each 1 grain, Extract each of Extract Hyoscyamus. Cannabis Indica % grain ; or Extract 3047. Hyoscyamus and Opium. — Hyoscyamus, Codeine, and Extract Extract Hyoscyamus 2 grains, Aqueous Cannabis Indica, each 2 grains, in each Extract Opium 1 grain; or Hyoscyamus suppository. SUPPOSITORIA— SUPPOSITORIES. 785 3049. Hyoscyamus, Coca, and Cannabis Indica. — Extract Hyoscya- mus 1 grain, Extract Coca 2 grains, Extract Cannabis Indica ]/ z grain ; or Extract Hyoscyamus 4 grains, Extract Coca 5 grains, Extract Cannabis Indica 2 grains, in each suppository. 3050. Morphine Sulphate or Ace- tate. — These are made with either the Sulphate or Acetate of Morphine, to contain T V, }s> l A>, %, %, or 1 grain of the salt. 3051. Morphine and Atropine. — Sulphate of Morphine l /% grain, Sulphate of Atropine -.j}^ grain ; or Sulphate of Morphine yi grain, Sulphate of Atro- pine 2^ grain, in each suppository. 3052. Morphine, Atropine, and Cocaine. — Sulphate of Morphine X grain, Sulphate of Atropine -j-J,,- grain, Hydrochlorate of Cocaine }i grain ; or Sulphate of Morphine %, grain, Sul- phate of Atropine T ^ v grain, Hydro- chlorate of Cocaine y, grain, in each suppository. 3053. Morphine, Atropine, Co- caine, and Cannabis Indica. — Sul- phate of Morphine y. grain, Sulphate of Atropine -j-J-j grain, Hydrochlorate of Cocaine l /£ grain, and Extract Can- nabis Indica ]/ 2 grain ; or Sulphate of Morphine x / 2 grain, Sulphate of Atro- pine T } i(i grain, Hydrochlorate of Co- caine Yz grain, Extract Cannabis Indica y 2 grain, in each suppository. 3054. Opium. — These are made to contain y§, yi, %, y, 1, 2, 3, or 4 grains each of Powdered Opium. 3055. Extract Opium. — These are made to contain %, y, 1, or 2 grains each of Aqueous Extract of Opium. 3056. Opium and Belladonna. — These are made in a great many pro- portions as follows : Powdered Opium %, grain, Extract Belladonna y grain ; Powdered Opium t grain, Extract Bella- donna % grain ; Powdered Opium 2 grains, Extract Belladonna y grain ; Powdered Opium 3 grains, Extract Bel- ladonna yi grain. 3057. Extract Opium and Bella- donna. — These are made in several proportions as follows : Aqueous Ex- tract Opium yi grain, Extract Bella- donna yi grain; Aqueous Extract Opium 1 grain, Extract Belladonna yi grain ; Aqueous Extract Opium \% grain, Ex- tract Belladonna y z grain ; Aqueous Extract Opium 2 grains, Extract Bella- donna y z grain; Aqueous Extract Opium 2 grains, Extract Belladonna 1 grain. 3058. Opium and Ipecac. — These are made with Powdered Opium 1 grain, Powdered Ipecac 1 grain ; Powdered Opium 2 grains, Powdered Ipecac 2 grains. ASTRINGENT. Those which contain a larger quantity of the medicinal agent than can well be contained in a 1 5-grain mould are made of a correspondingly larger size. 3059. Extract Belladonna and Acetate of Lead. — These are made with Extract of Belladonna \i grain, .\i etate of Lead, 1 '• grains ; or Kxtract of llclladonna y z grain, Acetate of Lead 3 grains. 3060. Extract Belladonna and Tannin Compound.— Kxtract Bella- donna y z grain, Tannin 5 grains, Sul- phate of Morphine y grain, Iodide of Lead 3 grains, in each. 3061. Extract Krameria. — These are made to contain 3 grains, 5 grains, or 10 grains of the Extract in each. 3062. Extract Stramonium and Acetate of Lead. — These are made witli Extract Stramonium 1 grain, Ace- tate of Lead 2 grains, in each. 786 SUPPOSITOK1A — SUPPOSITORIES. 3063. Extract Stramonium and Tannin. — These are made to contain Extract Stramonium 1 grain, Tannic Acid 5 grains, in each. 3064. Extract Stramonium and Tannin Compound. — Extract Stra- monium y z grain, Tannic Acid l / 2 grain, Carbonate of Lead 1 grain, Liquor Subacetate of Lead 2 minims, Creasote y 2 minim, in each. 3065. Gallic Acid, Ergot, and Digitalis. — These are made with Gal- lic Acid 2 grains, Extract Ergot 5 grains, Digitalis 1 grain ; or Gallic Acid 5 grains, Extract Ergot 10 grains, Digitalis 2 grains, in each. 3066. Opium and Acetate of Lead. — These are made of several propor- tions, as follows : Powdered Opium 1 grain, Acetate of Lead 2 grains ; Powdered Opium 2 grains, Acetate of Lead 2 grains ; Pow- dered Opium 1 grain, Acetate of Lead 5 grains ; Powdered Opium 2 grains, Acetate of Lead 5 grains. 3067. Tannic Acid. — These are made to contain 2 grains, 5 grains, or 10 grains of Tannin in each suppository. 3068. Tannic Acid and Bismuth. — These are made to contain Tannic Acid 5 grains, Bismuth Subnitrate 10 grains ; Tannic Acid 10 grains, Bis- muth 20 grains, in each. 3069. Tannic Acid and Opium. — A number of combinations are made as follows : Tannic Acid 2 grains, Powdered Opium 1 grain ; Tannic Acid 2 grains, Powdered Opium 2 grains ; Tannic Acid 5 grains, Powdered Opium 1 grain; Tannic Acid 5 grains, Powdered Opium 2 grains. 3070. Tannin, Extract Krameria, and Gallic Acid. — These are made to contain Tannic Acid 5 grains, Extract Krameria 1 grain, and Gallic Acid 2 grains ; or Tannic Acid 10 grains, Ex- tract Krameria 5 grains, Gallic Acid 4 grains. 3071. Tannin, Eucalyptol, and Iodoform. — These are made with Tan- nic Acid 5 grains, Eucalyptol 1 minim, Iodoform 2 grains ; or Tannin 20 grains, Eucalyptol 2 minims, Iodoform 5 grains, in each. 3072. Tannin, Bismuth, and Cor- rosive Sublimate. — Tannin 5 grains, Bismuth Subnitrate 5 grains, Corrosive Sublimate -^ grain ; or Tannin 10 grains, Bismuth Subnitrate 10 grains, Corrosive Sublimate ^ grain, in each suppository. 3073. Thymol and Bismuth. — Thymol 2 grains, Bismuth Subnitrate 10 grains ; or Thymol 1 grain, Bismuth Subnitrate 20 grains, in each. ANTISEPTIC. Many of these require to be made larger than the 1 5-grain size. 3074. Boric Acid.— These are made to contain 5 grains of Boric Acid in each. 3075. Boric Acid, Thymol, and Eucalyptus. — Boric Acid 5 grains, Thymol 2 grains, Oil Eucalyptus 1 minim ; or Boric Acid 10 grains, Thy- mol 1 grain, Oil Eucalyptus 3 minims, in each. 3076. Benzoic Acid, Corrosive Sublimate, and Resorcin. — These are made, Benzoic Acid 5 grains, Re- sorcin 10 grains, Corrosive Sublimate yV grain ; or Benzoic Acid 10 grains, Resorcin 10 grains, Corrosive Sublimate T V grains, in each. 3077. Iodoform. — These are made to contain 1, 2, or 3 grains of Iodoform in each suppository. 3078. Iodoform and Tannic Acid. — Iodoform 5 grains, Tannin 10 grains ; SUPPOSITORIA — SUPPOSITORIES. 787 or Iodoform 5 grains, Tannin 20 grains in each suppository. 3079. Iodoform, Thymol, and Re- sorcin. — Iodoform 2 grains, Thymol 1 grain, Resorcin 10 grains ; or Iodo- form 5 grains, Thymol 1 grain, Resor- cin 10 grains, in each suppository. 3080. Naphthalin Compound. — Naphthalin 2 grains, Borax 10 grains, Corrosive Sublimate ^ grain, Oil Euca- lyptus 2 minims ; or Naphthalin 3 grains, Borax 10 grains, Corrosive Sub- limate yV grain, Oil Eucalyptus 2 min- ims, in each. 3081. Salicylic, and Boric Acid with Thymol. — Salicylic Acid 5 grains, Boric Acid 5 grains, Thymol 2 grains ; or Salicylic Acid 10 grains, Boric Acid 10 grains. Thymol 5 grains, in each suppository. HYPNOTIC. Most of these Suppositories contain a larger quantity of medicine than can be made up into ordinary size suppositories, and must be made larger. 3082. Chloral Hydrate, Atropine, and Morphine.— Chloral Hydrate 10 grains, Sulphate of Atropine yJ,j grain, Sulphate of Morphine % grain ; or Chloral Hydrate 30 grains. Sulphate of Atropine T0Tr grain, Sulphate of Mor- phine % grain, in each suppository. 3083. Chloral Hydrate, Mono- bromated Camphor, and Hyoscy- amine. — Chloral Hydrate 15 grains, Monobromated Camphor 5 grains, Hy- drochlorate of Ilyoscyamine T J- ff grain ; or Chloral Hydrate 20 grains. Mono- bromated Camphor 10 grains, Hydro- chlorate of Ilyoscyamine K ' grain in each. 3084. Chloral Hydrate, Morphine, and Atropine. — Chloral Hydrate 15 grains, Sulpha'e of Morphine % grain, Sulphate of Atropine ,.!,, grain; or Chloral Hydrate 20 grains, Sulphate of Morphine % grain, Sulphate of Atro- P'" c 100 g ra i n . in each. 3085. Lupuline, Codeine, and Hyoscine. — Lupuline 5 grains, Co- deine 1 grain, Hyoscine Hydrobromate too grain ; or Lupuline 10 grains, Codeine 2 grains, Hyoscine Hydrobro- mate ^jy grain, in each. 3086. Lupuline and Opium Com- pound. — Lupuline 5 grains, Extract Hyoscyamus 1 grain, Extract Cannabis Indica 1 grain, Extract Opium % grain; or Lupuline 15 grains, Extract Hyoscy- amus 2 grains, Extract Cannabis In- dica 2 grains, Extract Opium 1 grain, in each. 3087. Lupuline and Cannabis Indica Compound. — Lupuline 5 grains, Extract Hyoscyamus 1 grain, Monobromated Camphor 2 grains, Ex- tract Cannabis Indica %, grain ; or Lu- puline 15 grains, Extract Hyoscyamus 2 grains, Monobromated Camphor 2 grains, Extract Cannabis Indica 1 grain, in each. Urethral Suppositories. • Suppositories are made long and slim and of a uniform size, '.. inch or smaller, suitable for inserting in the urethra. They may be made up in the same manner that pills are made into rolls before cutting. They are 788 SUPPOSITORIA — SUPPOSITORIES. used for gonorrhoea, gleet, stricture, and other irritations or ailments of the urethra. They are usually made from two to three inches long. 30S8. Bismuth and Lead. — Sub- carbonate of Bismuth 2 grains, Carbon- ate of Lead 1 grain ; or Subcarbonate of Bismuth 3 grains, Carbonate of Lead 1 grain, in each. 3089. Calomel and Chlorate of Potassium. — Calomel 1 grain, Chlo- rate of Potassium 1 grain ; or Calomel 2 grains, Chlorate of Potassium 3 grains, in each. 3090. Calomel, Corrosive Subli- mate, and Eucalyptus. — Calomel 1 grain, Corrosive Sublimate ^5 grain, Oil Eucalyptus 1 minim ; or Calomel 5 grains, Corrosive Sublimate ■£$ grain, Oil Eucalyptus 1 minim, in each. 3091. Copaiba and Tannin.— Co- paiba 2 minims, Tannic Acid 2 grains ; or Copaiba 3 minims, Tannic Acid 3 minims in each. 3092. Copaiba and Bismuth. — Copaiba 2 minims, Subnitrate of Bis- muth 3 grains ; or Copaiba 3 minims, Subnitrate of Bismuth 5 grains, in each suppository. 3093. Copaiba, Cubebs, and Sali- cin. — Copaiba 2 minims, Oil of Cubebs 1 minim, Salicin 3 grains ; or Copaiba 2 minims, Oil Cubebs 1 minim, Salicin 3 grains, in each. 3094. Hydrastine and Salicin. — Hydrastine }4 grain, Salicin 2 grains ; or Hydrastine 1 grain, Salicin 3 grains in each. 3095. Iodoform, Tannin, and Thy- mol. — Iodoform 2 grains, Tannic Acid 1 grain, Thymol ]/ 2 grain ; or Iodoform 2 grains, Tannic Acid 1 grain, Thymol x /z grain, in each. 3096. Zinc and Copper Sulphates. — Sulphate of Zinc 1 grain, Sulphate of Copper 1 grain ; or Sulphate of Zinc 3 grains, and Sulphate of Copper 1 grain, in each. Vaginal Suppositories. These Suppositories are made much larger, and usually of an oviform shape. Mould may be obtained for making them, or for extemporaneous use they may be formed by hand into the required shape. The formulae are as follows : 3097. Copaiba and Tannin. — Copaiba 30 grains, Tannic Acid 20 grains, Oil Cloves 1 minim ; or Copaiba 15 grains, Tannic Acid 10 grains, Oil Cloves 2 minims, in each. 3098. Iodoform and Corrosive Sublimate. — Iodoform 5 grains, Cor- rosive Sublimate ^V grain ; or Iodoform 10 grains, Corrosive Sublimate -^ grain, in each. 3099. Iodoform and Tannin. — Iodoform 5 grains, Tannic Acid 15 grains ; or Iodoform 5 grains, Tannic Acid 30 grains, in each. 3100. Salicylic, Boric, and Tan- nic Acids. — Salicylic Acid 10 grains, Boric Acid 5 grains, Tannic Acid 20 grains ; or Salicylic Acid 15 grains, Boric Acid 5 grains, Tannic Acid 20 grains, in each. 3101. Tannic and Boric Acid. — Tannic Acid 40 grains, Boric Acid 5 grains ; or Tannic Acid 40 grains, Boric Acid 10 grains, in each. 3102. Tannin and Bismuth. — Tannic Acid 20 grains, Subnitrate of Bismuth 20 grains ; or Tannic Acid 20 grains, and Subnitrate of Bismuth 40 grains, in each. 3103. Tannin, Bromide, and Chlo- rate of Potassium. — Tannic Acid 20 grains, Bromide of Potassium 15 SUPPOSITOKIA — SUPPOSITORIES. 789 grains, Chlorate of Potassium 10 grains; 3106. Zinc and Thymol. — Oxide or Tannic Acid 35 grains, Bromide of of Zinc 5 grains, Sulphocarbolate of Potassium 20 grains, Chlorate of Potas- Zinc 10 grains, Thymol 2 grains ; or sium 10 grains, in each. Oxide of Zinc 10 grains, Sulphocarbol- 3104. Nitrate and Acetate of ate of zinc 20 grains, Thymol 5 grains, Lead. — Nitrate of Lead 2 grains, Ace- in eacn - tate of Lead 5 grains ; or Nitrate of 3107. Resorcin Salicin and Bis- Lead 5 grains, and Acetate of Lead 10 muth. — Resorcin 5 grains, Subnitrate grains, in each. of Bismuth 20 grains, Salicin 10 grains ; 3105. Lead Bismuth and Euca- or Resorcin 10 grains, Subnitrate of typtol.— Carbonate of Lead 10 grains, Bismuth 30 grains, and Salicin 10 Subcarbonate of Bismuth 10 grains, grains, in each. Eucatyptol 2 minims; or Carbonate of 3108. Salicin and Cocaine. — Sali- Lead 10 grains, Subcarbonate of Bis- cin 20 grains, Hydrochlorate of Cocaine muth 10 grains, Eucalyptol 2 minims, ^ grain ; or Salicin 40 grains, Hydro- in each. chlorate of Cocaine 1 grain, in each. Other Suppositories. Besides the Suppositories enumerated, there are Aural Suppositories, con- taining small quantities of medicinal substances in small oblong suppositories, -and Nasal Suppositories, also small, and containing small quantities of medic- inal agents mostly of an antiseptic nature. These are but little used, and it is not necessary to give their composition here. The Suppositories of the Br. P. are as follows : 3109. Suppositoria Acidi Carbolici cum Sapone — Carbolic Acid Sup- positories. — Carbolic Acid 12 grains, Curd Soap 180 grains, Glycerine of Starch 40 grains, or a sufficiency. Mix the ingredients so as to form a paste of suitable consistence, and make 12 Suppositories by hand. 3110. Suppositoria Acidi Tannici— Tannic Acid Suppositories.— Tan- nic Acid 36 grains, Oil of Theobroma 144 grains. Make 12 Suppositories by running in moulds. 31 1 1. Suppositoria Acidi Tannici cum Sapone— Tannic Acid Sup- positories with Soap. — Tannic Acid 36 grains, Glycerine of Starch 2,0 grains, Curd Soap in powder 100 grains, Starch in powder, a sufficiency. Mix, roll and mould by hand into \z Suppositories. 3112. Suppositoria Hydrargyri — Mercurial Suppositories. — Ointment of Mercury 60 grains, Oil of Theobroma 120 grains. Make into 12 Supposi- tories by wanning them gently together and running into moulds. 31 13. Suppositoria Iodoformi — Iodoform Suppositories. Iodoform in powder 36 grains, Oil of Theobroma 144 grains. Make into 1 2 Suppositories. 3114. Suppositoria Morphinae -;1/^; phine Suppositories. Hydrochlo- rate of Morphine 6 grains, Olycerine of Starch 30 grains; Curd Soap in 790 SUPPOSITORIES. SVRUPI — SYRUPS. powder ioo grains, Starch in powder, a sufficiency. Make 12 Suppositories by hand. 31 15. Suppositoria Morphinae cum Sapone — Morphine Suppositories with Soap. — Hydrochlorate of Morphine 6 grains, Glycerine of Starch 30 grains, Curd Soap in powder 100 grains, Starch in powder, a sufficiency. Make 12 Suppositories by hand. 31 16. Suppositoria Plumbi Composita — Compound Lead Suppositories. — Acetate of Lead 36 grains, Opium in powder 12 grains, Oil of Theobroma 132 grains. Make 12 Suppositories by running in moulds. A few other Suppositories have a popular sale as proprietary remedies, as : 31 17. Pile Suppositories. — These may be variously made, but as good a formula as any is Opium in powder 2 grains, Galls in fine powder 10 grains, with sufficient Oil of Theobroma to make a 30-grain Suppository. 31 18. Purgative Suppositories. — These may be most conveniently made of powdered Elaterium 1 grain, made up with Oil of Theobroma into a sup- pository. 31 19. Vermifuge Suppositories — For pin worms. — Aloes 10 to 20 grains in powder made up into 30-grain Suppositories. SYRUPI— SYRUPS. Syrups as understood in pharmacy are concentrated Solu- tions of Sugar in Water or other aqueous liquids, containing, usually, some flavoring or medicinal ingredients. They are prepared by dissolving the sugar in the medicinal solution either by the aid of heat or by agitation, or stirring cold, the latter method being now quite generally employed as the flavor of the preparation is better retained by the cold process. The best process for making Syrups is by water-bath perco- lation, as by this method the making of the Syrup is facili- tated by the heat without exposure, and the flavor and strength of the preparation is unimpaired. Only the best quality of granulated sugar should be used for making Syrups, and the water should, if not distilled, be free from all impurities. Rain water boiled and filtered is suf- ficiently pure for most purposes. Many of the Syrups do not keep well during the summer. Such Syrups should only be made in small quantities and if SYRUPI — SYRUPS. 791 admissible should be rubbed in a mortar with a few drops only of Oil of Cloves, which prevent them from spoiling for a long time. Syrups should be made slightly heavier of sugar for summer use than when designed to be used in the winter. A great number of Syrups are employed in pharmacy, but only a comparatively small number are official. Those official in the U. S., Br., and German Pharmacopoeias will first be considered, and then the more important unofficial Syrups. 3120. Syrupus — Syrupus Simplex. Syrup. — Simple Syr up. The U. S. 1880 formula is: Sugar, in coarse powder, . 65 parts or 28^6 ounces av. Distilled water, enough to make 100 parts or 2 pints. Two pints of Syrup as thus prepared weighs as follows : Weight in grains, 19102 Weight in av. ounces (nearly), .... AZ 2 A Specific gravity, i-3io Dissolve the Sugar with the aid of heat in 1 1 fl. ounces of Distilled Water, raise the temperature to the boiling point, and strain the solution while hot. Then incorporate with the solution enough Distilled Water, added through the strainer, to make the Syrup measure two pints, or weigh as above. This is dispensed as Simple Syrup and used as the basis of other Syrups. MADE BY WATER-BATH PERCOLATION. Sugar, granulated, .... 7 pounds i ^ ounces av. Distilled, or pure Water, enough to make a gallon. Having covered the perforated diaphragm of the water-bath percolator with a piece of muslin or canton flannel, put the sugar upon it in the percolator, and add to it 3 pints of water, heat the solution to boiling, with occasional stirring, then draw off by the stop-cock and add enough Distilled Water through the percolator to make a gallon. 792 SYRUPI — SYRUPS. It will readily be seen that this is the most convenient and practical way to make Simple Syrup. It is not only made, but strained or filtered at the same operation, and produces a clear, bright syrup. If it is desirable to make the syrup (or any syrup) without heat, it may be made in the same manner, simply omitting the heat. For other purposes Syrup is variously made, as Flavored Syrup, for making elegant preparations, Soda Water Syrup for making soda water, etc. 3121. Syrupus Acaciae. Syrup of Acacia — Syrup of Gum Arabic. Mucilage of Acacia, . . 25 parts or 4^ fl. ounces. Syrup 75 parts or 12 fl. ounces. Mix them. This Syrup should be freshly made when required for use. The proportion of one part by measure of mucilage to three parts of syrup, although not exactly correct, is accurate enough for making this syrup extemporaneously. This is used in cough mixtures and as a vehicle for other medicines. MADE BY WATER-BATH PERCOLATION. Fenners Formula. Acacia, granulated, 3 ounces av. Sugar, granulated, 24 ounces av. Oil of Cloves, 10 minims. Water, enough to make 2 pints. Dissolve the Acacia by stirring it from time to time in eight ounces of water, When it is dissolved put the sugar in the water-bath percolator and add the solution and four ounces of water to it ; heat gently and stir occasionally until the sugar is dissolved, then draw off by the stop-cock and add enough water through the percolator to make two pints of the syrup. Rub the Oil of Cloves with an ounce of the syrup and mix it with the remainder by agitation. Syrup Acacia made in this manner will keep sweet through the summer. SYRUPI — SYRUPS. 793 3122. Syrupus Acidi Citrici. Syrup of Citric Acid. Citric Acid 8 parts or 150 grains. Water, 8 parts or 2^ fl. drachms. Spirit of Lemon, . . 4 parts or 95 minims. Syrup, 980 parts or 2 pints. Mix the Spirit of Lemon with the Syrup contained in a bottle ; then add, gradually, the Citric Acid, dissolved in the water, shaking the bottle after each addition until the whole is thoroughly mixed. This is used chiefly for flavoring. 3123. Syrupus Acidi Hydriodici. Syrup of Hydriodic Acid. Iodine, 10 parts or 190 grains. Alcohol, 80 parts or 4 fl. ounces. Syrup, 150 parts or 5 fl. ounces. Sugar, 500 parts or 22 fl. ounces. Spirit of Orange, ... 5 parts or 2 fl. drachms. Distilled water, sufficient to make 1000 parts or 2 pints. F'or directions for making see U. S. P. 1880. As a current of hydrosulphuric acid gas is required to be passed through this preparation during the process of making, it will be made by but few druggists, therefore the directions for making are not here repeated. This Syrup contains one per cent, of absolute Hydriodic Acid. The dose is a teaspoonful. 3124. Syrupus Allii. Syrup of Garlic. Fresh Garlic, sliced and bruised, 15 parts or Gyi ounces av. Sugar, in coarse powder, ... 60 parts or 26 ounces av. Diluted Acetic Acid 40 parts or 1 pint. Macerate the Garlic for four days with ten ounces of Diluted Acetic Acid and express the liquid. Then mix the residue 794 SVRUPI — SYRUPS. with the remainder of the Acid and again express until enough additional liquid has been obtained to make the whole, when filtered, measure a pint. Then pour the filtered liquid upon the Sugar contained in a bottle and agitate occasionally until it is dissolved. Keep the Syrup in well stopped, filled bottles in a cool place. This is used in cough and worm medicines. A Compound Syrup of Garlic is made with Garlic l / z ounce, Aniseed y 2 ounce, Elecampane Root 3 drachms, Liquorice Root 2 drachms, macerated with Brandy 24 fl.ounces, and the liquid made into a Syrup with 1 % pound of Sugar. 3125. Syrupus Althaea. Syrup of Althcea. This is official in the U. S. and German Pharmacopoeias, the formula being about the same in each. Althaea root, cut, ... 4 parts or 1 ounce av. Sugar, granulated, ... 60 parts or 15 ounces av. Water, a sufficient quantity to make 100 parts or 1 pint. Having washed the Althaea with cold Water, pour upon it fourteen ounces of cold Water and macerate for one hour, stirring frequently ; then drain through flannel without ex- pressing. To nine fl.ounces of the drained liquid add the Sugar and dissolve it by agitation without heat. This Syrup should be freshly made, when required for use. This is a demulcent Syrup used for coughs and as a diu- retic. Dose, a teaspoonful or more. 3126. Syrupus Amygdalae. Syrup of Almonds (Orgeat). Sweet Almond, ... 10 parts or 5 ounces av. Bitter Almond, ... 3 parts or 1*4, ounces av. Sugar, 50 parts or 25 ounces av. Orange Flower Water, 5 parts or 2}& fl.ounces. Water, enough to make 100 parts or 2 pints. Having blanched the Almonds rub them to a very fine paste, adding, during the trituration, \]/ 2 ounces of Water and 5 ounces of Sugar. Mix the paste thoroughly with the Orange SYRUPI — SYRUPS. 795 Flower Water and 15 ounces of Water, strain with strong ex- pression, and add enough Water to the dregs to obtain, after renewed expression, 25 fl. ounces of strained liquid. To this add the remainder of the Sugar, dissolve it by agitation, with- out heat, and strain through muslin. Keep the Syrup in well- stopped, filled bottles in a cool place. (U. S. 1880.) The German formula directs a smaller proportion of Bitter Almonds, but is otherwise about the same. It is used mainly for flavoring. A Syrup of Bitter Almond for flavoring may be made with Essence of Bitter Almond ]/ 2 fl. ounce mixed with 1 pint of Syrup. 3127. Syrupus Aurantii. Syrup of Orange. The U. S. formula is : Sweet Orange Peel, de- prived of the inner white layer, and cut into small pieces, . . 5 parts or 2]/ 2 ounces av. Alcohol, 5 parts or 3 fl. ounces. Precipitated Phosphate of Calcium, 1 part or x / 2 ounce av. Sugar, 60 parts or 30 ounces av. Water, a sufficient quan- tity to make .... 100 parts or 34 fl. ounces. Macerate the Orange Peel with the Alcohol for seven days, then express the liquid ; rub this with the Precipitated Phos- phate of Calcium and 15 ounces of Water gradually added; filter the mixture and pass enough Water through the filter to make the filtrate weigh 40 parts or measure 19^ ounces. Lastly, add the Sugar, dissolve it by agitation, without heat, and strain. Used mainly for flavoring. The Br. P. directs Tincture of Orange Peel 1 fl. ounce, Syrup 7 fl. ounces, to be mix'ed together. The G. P. formula is: Orange Peel 5 parts, White Wine 45 parts, macerate for 2 days and express, then add to 40 parts of expressed liquid 60 parts of Sugar and dissolve. 796 SYRUPI — SYRUPS. FENNER S FORMULA. As Syrup of Orange is used only for its agreeable flavor, and has no medicinal value, it seems unnecessary to go to so much trouble to make it when a simpler method will answer the purpose as well. The following formula is therefore given, which will make a fine preparation, provided only a good quality of Oil of Orange is used : Oil of Orange 40 minims. Alcohol, 2 fi. drachms. Carbonate of Magnesium, 80 grains. Sugar, granulated, 28 ounces av. Water, sufficient to make 2 pints. Dissolve the Oil of Orange in the Alcohol and rub with the Carbonate of Magnesium in a mortar, gradually adding 12 fl. ounces of Water ; filter the mixture and add enough Water through the filter to make 14 fl. ounces ; dissolve the Sugar in the filtrate by agitation or percolation and add enough Water, if necessary, to make 2 pints of the Syrup. 3128. Syrupus Aurantii Florum. Syrup of Orange Flowers. Sugar, in coarse powder, . 65 parts or 28^8 ounces av. Orange Flower Water, 35 parts or enough to make 2 pints. Dissolve the Sugar as nearly as possible by agitation in 14 fl. ounces of Orange Flower Water, then add enough Orange Flower Water to make 2 pints of the Syrup and agitate until dissolved. The amount of Sugar directed is a little more than will readily dissolve by agitation. The 1870 revision directs to use gentle heat. It may be readily made to dissolve by water- bath percolation without injuring its flavor. The formulas of the Br. and German Pharmacopoeias direct the Sugar first to be dissolved in distilled Water by heat, and Orange Flower Water added when nearly cold, to make of the desired specific gravity. This Syrup is used for flavoring other medicines. SYRUPI — SYRUPS. 797 3129. Syrupus Calcii Lactophosphatis. Syrup of Lactophosphate of Calcium {Lime). Precipitated Phosphate of Calcium (Lime), . . 22 parts or 1 ounce av. Lactic Acid, concentrated, 33 parts or 9^ fl. drachms. Orange Flower Water, . 80 parts or 3 fl. ounces. Sugar, in coarse powder, 600 parts or 28 ounces av. Hydrochloric Acid, \ Water of Ammonia, - each a sufficient quantity to make Water, ) IOO ° parts or about 2 pints. Mix the precipitated Phosphate of Calcium with 300 parts or 13 fl. ounces of cold W T ater and add enough Hydrochloric Acid to dissolve it. Filter the solution and add to the filtrate 1200 parts or 3 pints of cold Water, and Water of Ammonia until slightly in excess, which may be distinguished by the odor of Ammonia after standing a few moments. Allow the precipitate to subside, pour off the supernatant Water, pour on more Water, agitate, and repeat the operation several times until the precipitate is thoroughly washed, then pour it upon a muslin strainer, drain and press out the Water, and, at once, dissolve the magma in the Lactic Acid. Then add the Orange Flower Water and enough Water to make the solution weigh about 350 parts or measure 14 fl. ounces ; filter, and pass enough Water through the filter to make the filtrate weigh 400 parts or measure 17 fl. ounces. Lastly, add to this the Sugar and dissolve it by agitation or percolation, without heat, and strain. This is essentially the same as was formerly published in FENNER'S FORMULARY. The addition of a fl. drachm of Hydro- chloric Acid to the finished Syrup tends to prevent the pre- cipitation whichis so common in this preparation. In fact, as the Syrup is prepared by many manufacturers, it contains hardly any Lactic Acid, it place being supplied by Hydro- chloric Acid, which is cheaper and makes a more stable preparation. This Syrup is given as a nutritive tonic in doses of a teaspoonful or mure. Another formula for this Syrup is given among the Unofficial Syrups. 798 SYRUPI — SYRUPS. 3130. Syrupus Calcis. Syrup of Lime — SaccJiaratcd Solution of Lime. Lime (unslacked), ... 5 parts or 1 ounce av. Sugar, in coarse powder, . 30 parts or 6 ounces av. Water, a sufficient quantity to make 100 parts or 20 ounces av. Triturate the Lime and Sugar together in a mortar, then add the mixture to 12 ounces of boiling Water, contained in a bright copper or tinned iron vessel, and boil the mixture for five minutes, constantly stirring ; dilute it with an equal vol- ume of W T ater and filter it through white paper. Finally, evaporate the Syrup to 100 parts or 20 ounces avoirdupois. This is a new U. S. official, but a similar preparation has been for some time official in the British Pharmacopia under the name of Liquor Calcis Saccharatus. It is used as an antacid. Dose, teaspoonful or more. 3131. Syrupus Cerasorum. G. P. Syrup of Cherries. Bruise black sour Cherries with the seeds (stones) and set them aside in a covered vessel at a temperature of about 20°C, stirring frequently until a small filtered portion yields a clear mixture with half its volume of Alcohol; then express and filter. The liquid may be called Cherry Juice. Then take Cherry Juice, 1 pint or 35 parts. Sugar, 2 pounds or 65 parts. Dissolve the Sugar in the Juice. This is a finely-flavored acid Fruit Syrup. Other Fruit Syrups may be prepared in the same manner. 3132. Syrupus Cinnamomi. G. P. Syrup of Cinnamon — Zimmet Syrup. Cinnamon, in coarse powder, 10 parts. Cinnamon Water, 50 parts. Sugar, 60 parts. Water, 40 parts. SYRUPI — SYRUPS. 799 SO : grains. I# fl. drachms, I fl. ounce. Macerate the Cinnamon in the Cinnamon Water for 2 days, strain and filter, then add the Sugar and dissolve. This Syrup is used as a flavoring for other medicines. 3133. Syrupus Chloral. Br. Syrup of Chloral. Hydrate of Chloral Distilled Water, Simple Syrup, sufficient to make . Dissolve the Chloral in the Water and add enough Syrup to make the measure I fl. ounce. This Syrup contains 10 grains of Choral in a fl.drachm and is used as a hypnotic and anodyne. It should be freshly made when wanted. A teaspoonful contains 10 grains of the salt. The dose is 1 to 4 fl. drachms. 3134. Syrupus Ferri Bromidi. Syrup of Bromide of Iron. Iron, in the form of fine wire cut in small pieces, 30 parts or \y 2 ounces av. Bromine, 75 parts or 3^ ounces av. Sugar, in coarse powder, 600 parts or 30 ounces av. Distilled Water, a suffi- cient quantity to make 1000 parts or about 2 pints. Introduce the Iron into a flask of thin glass of suitable capacity, add to it 200 parts or 9 fl. ounces of distilled Water, and afterwards the Bromine; shake the mixture occasionally until the reaction ceases and the solution has acquired a green color and has lost the odor of Bromine. Place the Sugar in a porcelain capsule and filter the solution of Bromide of Iron into the Sugar; rinse the flask and the Iron Wire with go parts or 4 fl. ounces of distilled Water and pass the washings through the filter into the Sugar; stir the mixture with a porcelain or wooden spatula, heat it to the boiling point on a sand-bath and, having strained the Syrup through linen into a tared 800 SYRUPI — SYRUPS. bottle, add enough distilled Water to make the product weigh iooo parts or measure 33 fl. ounces. Lastly, shake the bottle and transfer its contents to small vials, which should be well filled, corked, and kept in a cool dark place. This Syrup, which has previously been furnished chiefly by manufacturing chemists, is now made officinal. It should con- tain 10 per cent, by weight of Ferrous Bromide. The dose is 15 to 60 minims. 3135. Syrupus Ferri Iodidi. Syrup of Iodide of Iron. Iron, in the form of fine wire cut in small pieces, 25 parts or 532 grains. Iodine, 82 parts or 4 ounces av. Sugar, in coarse powder, 600 parts or 28 ounces av. Distilled Water, a suffi- cient quantity to make 1000 parts or . 2 pints. Introduce the Iron into a flask of thin glass of suitable capacity, add to it 200 parts or 10 fl. ounces of distilled Water, and afterwards the Iodine ; shake the mixture occasionally until the reaction ceases and the solution has acquired a green color, and lost the odor of Iodine. Place the Sugar in a por- celain capsule, and filter the solution of Iodide of Iron into the Sugar. Rinse the flask and Iron Wire with 90 parts or 4 fl. ounces of distilled Water, and pass the washings through the filter into the Sugar. Stir the mixture with a porcelain or wooden spatula, heat it to boiling on a sand bath, and having strained the syrup into a tared bottle, add enough distilled Water to make the product weigh 1000 parts or measure 2 pints. Lastly, shake the bottle, and transfer its contents to small vials, which should be securely corked, and kept in a cool, dark place. This Syrup contains 10 per cent, of Ferrous Iodide. The Br. and German contain only about 5 per cent. The 1880 preparation contains more Sugar than the 1870, and is there- fore a more stable preparation. The dose is 15 to 60 minims. Many methods have been proposed for preventing the decomposition and change of color of Syrup of Iodide of SYRUPI — SYRUPS. 801 Iron, but if carefully made by the present official formula, and preserved as directed, it seldom changes. Should any change be noticeable, a very small crystal of Ferrous Sulphate will generally restore it. A so-called " Tasteless Syrup of Iodide of Iron " (which see) is furnished by manufacturing chemists, and is quite popular with many physicians. 3136. Syrupus Ferri Oxydati Solubilis. G. P. Syrup of Oxide of Iron. Saccharated Oxide of Iron, \ o f of each equal parts by \Y™ e p r,* '. ; ; ; ; •; ; f wd § ht - Mix them and dissolve. It contains I per cent, of Iron and is given as a mild ferruginous tonic. The dose is a teaspoonful 3137. Syrupus Ferri Phosphatis. Br. Granulated Sulphate of Iron, . . . 224 grains. Phosphate of Sodium, 200 grains. Bicarbonate of Sodium, 56 grains. Concentrated Phosphoric Acid (Br. P.), \)/± fl. ounces. Refined Sugar, 8 ounces av. Distilled Water, 8 fl. ounces. Dissolve the salts separately, mix, and wash the precipitate as directed page 37, press the residue and dissolve it in the Phosphoric Acid, filter the solution, add the Sugar, and dis- solve, making the measure 12 fl. ounces. This contains about one grain of Phosphate of Iron in a fl. drachm. This Syrup is much more readily prepared by mixing Solution Phosphate of Iron (1936), . 2 fl. drachms. Syrup, 15 fl. ounces. Or, by dissolving Phosphate of Iron in scales 128 grains in 6 fl. ounces hot Water, adding 14 ounces av. of Sugar, and then enough Water to make a pint. The dose is a teaspoonful or more as an iron tonic. 802 SYRUPI — SYRUPS. 3138. Syrupus Ferri, Quininae et Strychninae Phosphatum. U. S. Syrup of the Phosphates of Iron, Quinine and Strychnine. Phosphate of Iron (scale salt), 133 parts or 200 grains. Quinine, 133 parts or 200 grains. Strychnine, 4 parts or 6 grains. Phosphoric Acid, .... 800 parts or 2 fl. ounces. Sugar, in coarse powder, . 6000 parts or 21 ounces av. Distilled Water, a sufficient quantity to make . . . 10000 parts or 2 pints. Add the Phosphate of Iron to 2500 parts, or y 2 pint of dis- tilled Water in a tared bottle large enough to hold the finished Syrup and agitate freely until the salt is dissolved. Having added the Phosphoric Acid to the solution, triturate the Qui- nine and Strychnine gradually with the mixture in a mortar until they are dissolved, then return the solution to the bottle and add enough Distilled Water to make the liquid weigh 4000 parts or measure 12 fl. ounces. Lastly, add the Sugar, dissolve it by agitation, without heat, and filter through paper. Keep the Syrup in well-stopped vials in a cool, dark place. This new official is entirely unlike the unofficial prepara- tions bearing the same name. In making it the new officinal Phosphate of Iron in scales is to be used, and the alkaloids Quinine and Strychnine ; the Phosphoric Acid is also the new officinal 50 per cent, solution. The unofficial preparation of this name is more familiarly known as Easton's Syrup, the formula for which is as follows : 3139. Syrup Phosphates of Iron, Quinine and Strychnine. Easton's Syrup. This preparation has been much used in the past, but is now superseded by the U. S. official syrup. As some druggists may still wish to prepare it, the formula is given : Sulphate of Iron, 1% ounce av. Phosphate of Sodium 1 }( ounce av. Quinine (alkaloid), 1 ounce av. Strychnine (alkaloid), 8 grains. Phosphoric Acid (1880) 4 fl. ounces. Sugar 4 pounds av. Water, a sufficient quantity. SYRUPI — SYRUPS. 803 Dissolve the Sulphate of Iron and the Phosphate of Sodium each separately in a quart of water, add the Iron solution to the Sodium solution gradually and with constant stirring, and wash the precipitate as directed (page 37) until the washings are tasteless ; then collect the precipitate, drain and press quickly, and dissolve in the Phosphoric Acid. Add sufficient Water to the solution to make 36 fl.ounces, dissolve the Quinine and Strychnine in the Solution, filter, and dissolve the Sugar in the filtrate. The dose is a tea- spoonful, as a tonic, containing about 1 grain each Iron and Quinine, and ^ grain Strychnine. 3140. Syrupus Hemidesmi. Br. Syrup of Hemidesmus — {Indian Sarsaparilld). Hemidesmus Root, 4 ounces av. Refined Sugar, 28 ounces av. Boiling Distilled Water, 20 fl.ounces. Infuse the Hemidesmus Root in the Water in a covered vessel for 4 hours and strain. Set it by till the sediment sub- sides ; then decant the clear liquid, add the sugar and dissolve by aid of a gentle heat. This is used as an alterative and blood purifier. The dose is a teaspoonful. Syrup of Sarsaparilla of any other kind may be made in the same proportions and manner. 3141. Syrupus Hypophosphitum. Syrup of Hypophosphites. The U. S. official formula is : Hypophosphite of Calcium (Lime), 35 parts or 700 grains. Hypophosphite of Sodium (Soda) 12 parts or 240 grains. Hypophosphite of Potas- sium, 12 parts or 240 grains. Citric Acid, 1 part or 20 grains. Spirit of Lemon, .... 2 parts or 48 minims. Sugar, in coarse powder, . 500 parts or 23 ounces av. Water, a sufficient quantity to make 1000 parts or 2 pints. Mix the Hypophosphites and dissolve them by trituration in 350 parts, or one pint, of Water. Should there be any 804 SYRUPI — SYRUPS. residue undissolved allow the solution to settle, pour off nearly all of it and add the Citric Acid so that it may be dissolved. Then, having mixed the liquids, add the Spirit of Lemon and filter through paper, adding enough Water through the filter to make the whole weigh 500 parts or measure 21 fl. ounces. In this liquid dissolve the Sugar by agitation or percolation, without heat, and strain. Keep in well-stopped bottles. This is employed as a nutritive and tonic, especially for wasting diseases. The dose is a dessertspoonful. This Syrup has been in use for many years, under the gene- ral title of Syrup of Hypophosphites Compound, or Churchill's Syrup. The title " Syrup of Hypophosphites" seems insuffi- cient, as there are so many combinations called by that gene- ral name. Physicians prescribing Syrups of Hypophosphites should state the combination they desire by designating the Hypophosphite Salts, otherwise much confusion will result. In the officinal formula Citric Acid is used instead of Hypo- phosphorous Acid, which is usually directed in unofficinal formulae, and which seems more appropriate in the preparation. Formulae for the various combinations of Hypophosphites in syrups will be found further on in unofficial Syrups. 3142. Syrupus Hypophosphitum cum Ferro. Syr up of Hypophosphites with Iron. The U. S. P. formula is: Lactate of Iron, 1 part or 96 grains. Syrup of Hypophosphites, . . 99 parts or 1 pint. Dissolve the Lactate of Iron in the Syrup by trituration, and keep the Syrup in well-stopped bottles. This Syrup is also a new official, being designed to take the place of the popular unofficial "Syrup of Hypophosphites of Lime, Iron, Soda, and Potassa." Lactate of Iron is made to take the place of freshly precipi- tated Hypophosphite of Iron, which has usually been directed in the unofficinal formulae. This is given as a nutritive tonic in doses of a teaspoonful SYRUPI — SYRUPS. 805 3143. Syrupus Ipecacuanhas. Syrup of Ipecac. The U. S. formula is: Fluid Extract of Ipecac, . 5 parts or 2 fl. ounces. Syrup, 95 parts or 25 fl. ounces. Mix them. The present official Fluid Extract will mix with syrup and make a transparent preparation, because, by the process of preparing it, the resinous matter is removed; but the 1870 Fluid Extract and most manufacturers will make a " muddy" preparation, because of the precipitation of the resin of the Fluid Extract which is held in solution. The druggist may readily ascertain if his fluid extract con- tains resin by adding a few drops of it to water. If it contains resin it will have a muddy or cloudy appearance; if free from it, the result will be a clear solution. If it contains resin, the syrup should be made as follows : Fluid Extract of Ipecac, ..... 2 fl. ounces. Water, 13 fl. ounces. Sugar, 28 ounces av. Mix the Extract with the Water and half of the Sugar, and allow to stand until the Sugar is dissolved, then filter, add the remainder of the Sugar and dissolve by percolation or gentle heat, adding water if necessary to make two pints. If it is desired to make the Syrup of Ipecac from the root insteadsof the fluid extract, it may be made by the following formula : Ipecac, in moderately fine powder, . . 8 ounces av. Alcohol, 4 fl. ounces. Sugar, in coarse powder, 7 pounds av. Water, a sufficient quantity. Moisten the Ipecac with the Alcohol and pack moderately in the water-bath percolator: pour upon it 4 ounces of Water and set in a warm place for 24 hours; then heat very moder- ately and after one hour begin to percolate, adding Water to the drug and continuing the heat and percolation until two 806 SYRUPI — SYRUPS. pints have passed. Evaporate this by means of a water-bath — boiling it for a few moments — to a pint, and when cool filter, add to the filtrate enough Water to make 60 fl. ounces and dissolve the Sugar in the liquid by gentle heat, or water- bath percolation. The product should be one gallon of Syrup. Lastly, while still warm, put it in half-pint well-stopped bottles, and set away in a cool place. Syrup of Ipecac made and preserved in this manner will keep for years. It is given as an emetic in doses of ^ to 1 teaspoonful, repeated in 15 minutes if necessary, and is used in cough remedies. The German Syrup of Ipecac contains only 1 per cent, of Ipecac. The Br. P. contains no formula for it. 3144. Syrupus Krameriae. Syrup of Krameria (Rliatany). Fluid Extract Krameria, . 35 parts or 12 fl. ounces. Syrup, 65 parts or 20 fl. ounces. Mix them. As this Syrup is so little used, it is much more convenient to prepare it from the Fluid Extract as required ; 3 parts or fl. drachms of the Fluid Extract to 5 parts or fl. drachms of Syrup makes the preparation in the proper proportion. The dose is a teaspoonful or more as an astringent. 3145. Syrupus Lactucarii. Syrup of Lactucarium. Fluid Extract of Lactucarium, 5 parts or 2 fl. ounces. Syrup, . 95 parts or 29 fl. ounces. Mix them. This is used as an anodyne in doses of 1 to 3 fl.drachms. 3146. Aubergier's Syrup of Lactucarium. This preparation is much used in Europe and is occa- sionally called for in this country. Prof. Proctor, in the SYRUPI — SYRUPS. 807 A. J. P. 1866, page 290, furnished the following formula for its preparation : Lactucarium (German), y 2 ounce av. Sugar, granulated, I ounce av. Syrup, 4^ pints. Citric Acid, in powder, 60 grains. Orange Flower Water, 4 fl. ounces. Diluted Alcohol, ) , „. . . \ each a sufficient quantity. Water, ... I Triturate the Lactucarium with the Sugar until reduced to powder, put it into a funnel-shaped percolator, pour on diluted Alcohol until the Lactucarium is nearly exhausted, or until 10 fl. ounces have passed, evaporate to 2 fl. ounces and add it to the Syrup, previously heated by boiling, and mix. Continue the ebullition slowly until the whole measures 4 pints and 6 fl. ounces. Then add the Citric Acid and strain, and, lastly, when nearly cool, the Orange Flower Water, and mix them. This preparation is much inferior in strength to the officinal preparation. 3147. Syrupus Limonis. Syiup of Lemon. Lemon Juice, recently ex- pressed and strained, . . 40 parts or 17 fl. ounces. Lemon Peel, fresh, ... 2 parts or I ounce av. Sugar, in coarse powder, . 60 parts or 28 ounces av. Water enough to make . .100 parts or 2 pints. Heat the Lemon Juice to the boiling point, then add the Lemon Peel and let the whole stand closely covered until cold, filter, add enough Water through the filter to make the filtrate measure 17 fl. ounces, dissolve the Sugar in the filtered liquid by agitation, without heat, and strain. Syrup of Lemon will not keep long during the summer months. It is better preserved if put up hot, in small bottles, and kept in a cool place. The Br. formula is Lemon Juice 20 fl. ounces, Lemon Peel 2 ounces av., Sugar 2]/^ pounds av., made in the same manner. 808 SYRUPI — SYRUPS. 3148. Syrupus Liquiritiae. G. P. Syrup of Liquorice Root. Russian Liquorice Root, 20 parts. Water of Ammonia, 10 parts. Water, 100 parts. Alcohol, 10 parts. Syrup, sufficient to make 100 parts. Macerate the Liquorice Root in the mixed Water of Ammo- nia and Water for 10 hours, then express, heat the liquid once to boiling, and evaporate on a steam-bath to 10 parts ; to this add the alcohol, set aside for 12 hours, then filter and add to the filtrate enough Syrup to make 100 parts. This is used as a vehicle for bitter medicines and as a demulcent in cough mixtures, etc. 3149. Syrupus Mannae. G. P. Syrup of Manua. Pure Manna, 10 parts. Water, -40 parts. Sugar, 50 parts. Dissolve the Manna in the Water, filter and dissolve the Sugar in the filtrate. This is slightly laxative. 3150. Syrupus Menthae. G. P. Syrup of Peppermint. Peppermint, cut, IO parts. Alcohol, 5 parts. Water, 50 parts. Sugar, 60 parts. Moisten the Peppermint with the Alcohol, then add the Water, allow to stand one day, strain without pressure, and to 40 parts of the liquid add the Sugar, dissolve by gentle heat and when cold strain or filter. A great many other Syrups of Aromatic herbs may be pre- pared in the same manner. SYRUPI — SYRUPS. 809 3151. Syrupus Mori. Br. Syr up of Mulberries. Mulberry Juice, 20 fl. ounces. Refined Sugar, 36 ounces av. Rectified Spirit, 2^ fl. ounces. Heat the Juice to the boiling point and when cool, filter. Dissolve the Sugar in the filtered Liquid with the aid of heat and, when cool, add the Spirit. The dose is a fl. drachm or more. 3152. Syrupus Papaveris. The Br. formula is : Poppy Capsules freed from the seeds, and in No. 20 powder, 18 ounces av. Rectified Spirit, 8 fl. ounces. Refined Sugar, 2 pounds av. Boiling Distilled Water, a sufficiency. Mix the Poppy Capsules with 40 fl. ounces of the Boiling Water and infuse for 24 hours, stirring frequently; then pack in a percolator, and adding some more of the Water, allow the liquid to pass slowly until exhausted, or until about 160 fl. ounces have passed. Evaporate this percolate by water- bath to 44 fl. ounces, and when cold add the Spirit, allow to stand 12 hours, filter, distill off the Spirit, evaporate the re- maining liquor to 20 fl. ounces, add the Sugar and dissolve. The dose is 1 fl. drachm as an anodyne, etc. The German Pharmacopoeia directs this to be made the same as Syrup of Peppermint (which see). This is not official in the U. S. P. 3153. Syrupus Picis Liquidae. Syrup of Tar. Tar, 6 parts or 2^3 ounces av. Cold Water, .... 12 parts or 5 fl. ounces. Boiling Distilled Water, 50 parts or 22 fl. ounces. Sugar, in coarse powder, 60 parts or 26 ounces av. Upon the Tar contained in a suitable vessel, pour the Cold Water and stir the mixture frequently during 24 hours; then 810 SYRUPI — SYRUPS. pour off the water and throw it away. Pour the Boiling Dis- tilled Water upon the residue, stir the mixture briskly for fifteen minutes and set it aside for 36 hours, stirring occasion- ally. Decant the solution and filter. Lastly, in forty parts, or 17 fl. ounces of filtered solution, dissolve the Sugar by agita- tion, without heat. U. S. MADE BY WATER-BATH PERCOLATION. Fcnner s Formula. Tar, 2 ounces av. Cold Water, 4 fl. ounces. Pine Sawdust, 12 ounces av. Sugar, granulated, 28 ounces av. Boiling Water, a sufficient quantity. Pour the Cold Water upon the Tar and stir the mixture occasionally during 24 hours ; then pour off the water and mix the Tar intimately with the Pine Sawdust and pack firmly in the water-bath percolator. Pour upon it a pint of Boiling Water and keep at a moderate heat for 2 hours, then pour on more Boiling Water and begin to percolate, adding water and continuing the heat and percolation until 20 ounces have passed. Allow the percolate to stand until cool, then filter off a pint and dissolve the Sugar in the filtrate, by agitation or percolation. This is much used in cough mixtures, etc. 3154. Syrupus Pruni Virginianae. Syrup of Wild Cherry. 1880. Wild Cherry, in No. 20 powder, 12 parts or 5^ ounces av. Sugar, in coarse powder, 60 parts or 28 ounces av. Glycerin, 5 parts or 2 fl. ounces. Water, a sufficient quan- tity to make about . 2 pints. Moisten the Wild Cherry thoroughly with Water and mace- rate for 24 hours in a close vessel, then pack it firmly in "a cylindrical glass percolator and gradually pour Water upon it SYRUPI — SYRUPS. 811 until 15 ounces of percolate are obtained. Dissolve the Sugar in the liquid by agitation without heat, add the Glycerin and strain. U. S. MADE BY WATER-BATH PERCOLATION. Wild Cherry, in No. 20 powder, . . 5^ ounces av. Sugar, granulated, 28 ounces av. Glycerin, 2 fl. ounces. Water enough to make 2 pints. Moisten the Wild Cherry with six ounces of Water, and allow it to stand in a warm place for 24 hours in a covered vessel ; then pack in the water-bath percolator, pour a pint of Water upon it and heat very moderately, not over 100 F., for one hour, then begin to percolate, and continue the heat and percolation, adding Water to the drug, if necessary, until 14 fl. ounces have passed, dissolve the Sugar in the percolate while still warm, and add the Glycerin. Keep in small, well-stopped bottles in a cool place. Prepared and preserved in this man- ner this Syrup will keep through the summer. If the heat is kept within the limit mentioned, a much better preparation will result than when made by the cold process ; but too high a degree of heat vaporizes the Hydrocyanic Acid which has been developed by moistening the drug, and injures the preparation. This Syrup is much used as a sedative in cough remedies. 3155. Syrupus Rhamni Catharticae. G. P. Syrup of Buckthorn. This Syrup is officinal in the German Pharmacopoeia and is quite frequently called for in this country. It is made from the fresh juice of Buckthorn Berries, which is not obtainable in this country, by dissolving 65 parts of Sugar in 35 parts of the juice. We, therefore, have to depend upon the imported syrup, which can be obtained of wholesale druggists. Fluid Extract and Elixir of Buckthorn made from the Bark or Berries are now extensively used, and have nearly superseded, in this country, the Syrup made from the fresh juice. 812 SYRUPI — SYRUPS. 3156. Syrupus Rhei. Syrup of Rhubarb. The U. S. P. formula is: Rhubarb, sliced, ... 90 parts or 3^$ ounces av. Cinnamon, bruised, . . 18 parts or 340 grains. Carbonate of Potassium, 6 parts or 112 grains. Sugar, in coarse powder, 600 parts or 27 ounces av. Water, a sufficient quan- tity to make .... 1000 parts or 2 pints. Mix the Rhubarb, Cinnamon and Carbonate of Potassium with 420 parts or 20 fl. ounces of Water, and macerate the mixture in a glass or porcelain vessel for twelve hours. Then strain and filter, adding through the dregs, if necessary, enough Water to make the filtered liquid weigh 400 parts or measure a pint. Lastly, add the Sugar, dissolve it by agitation, with- out heat, and strain. MADE BY WATER-BATH PERCOLATION. Rhubarb, in No. 20 powder, ... 4 ounces. Cinnamon, in No. 20 powder, . . . 360 grains. Carbonate of Potassium, 120 grains. Sugar, granulated, 28 ounces av. Water, a sufficient quantity. Mix the Rhubarb and Cinnamon ; dissolve the Carbonate of Potassium in 4 ounces of Water, and, having moistened the drugs with the solution, set in a warm place in a closed vessel for 12 hours, then pack moderately in the water-bath percola- tor, pour upon them a pint of Water and heat very moderately for one hour ; then begin to percolate, adding Water to the drugs if necessary, and continue the heat and percolation until a pint of the percolate has passed; while still warm dissolve the Sugar in the liquid by agitation, and filter. This will be found much superior to the U. S. process for making this Syrup. The Br. P. formula is Rhubarb, Coriander, each 2 ounces av., Refined Sugar 24 ounces av., Rectified Spirit 8 fl. ounces, Dis- tilled Water 24 fl. ounces. Percolate with the mixed Spirit and SYRUPI — SYRUPS. 813 Water. Evaporate the percolate to 14 fl. ounces, filter, and dissolve the Sugar in the filtrate. The German formula is very much like the U. S. Syrup of Rhubarb is much used as a stomachic and for bowel troubles, acting first as a purgative and then as an astringent. The dose is 1 to 4 fl. drachms. 3157. Syrupus Rhei Aromaticus. Aromatic Syrup of Rhubarb — Spiced Syrup of Rhubarb. The U. S. P. formula of 1870 was: Rhubarb, in No. 50 powder, 600 grains. Cloves, in No. 50 powder, 60 grains. Cinnamon, in No. 60 powder, .... 60 grains. Nutmeg, in No. 50 powder 60 grains. Syrup, 3 pints. Diluted Alcohol, a sufficient quantity. ' Mix the powders, and, having moistened the mixture with a fl. ounce of Diluted Alcohol, introduce it into a conical perco- lator and pour Diluted Alcohol upon it until a half pint of tincture has passed ; add this to the Syrup, previously heated, and mix them thoroughly. The U. S. P. formula of 1880 is: Aromatic Tincture of Rhubarb, 10 parts or 2 fl. ounces. Syrup, 90 parts or 14 fl. ounces. Mix the Aromatic Tincture of Rhubarb with the Syrup. As the Aromatic Tincture of Rhubarb is the same as is pro- duced by percolating the drugs with Diluted Alcohol in the 1870 formula, the resultant preparation is very nearly the same in both cases. A formula for preparing this Tincture by water- bath percolation will be found under the head of Tinctures. 3158. Syrupus Rhceados. Br. Syrup of Red Poppy. Fresh Red Poppy Petals 13 ounces av. Refined Sugar 36 ounces av. Distilled Water, 20 fl. ounces. Rectified Spirit, 2 l / z fl. ounces. 814 SYRUPI — SYRUPS. Add the petals gradually to the Water heated in a' water- bath, frequently stirring, and afterwards, the vessel being re- moved, infuse for 12 hours, then press out the liquor, strain, add the Sugar and dissolve by heat ; when nearly cold add the Spirit and enough Water to make the product weigh 58 ounces av. This is used for imparting a red color to Syrups, and as a mild anodyne. Dose 1 fl. drachm or more. 3159. Syrupus Rosae. Syrup of Rose. This Syrup in the 1870 U. S. P. was called Syrupus Roscz Gallicce, or Syrup of Red Rose. It was prepared by percolat- ing 2 troyounces of Red Rose petals with Diluted Alcohol, reserving the first fl. ounce, evaporating the next 5 ounces that passed to 1^ ounces and mixing with 7 ounces of Water; 18 troyounces of Sugar was then dissolved in the liquid by gentle heat, and when cold the first one ounce reserved was added and thoroughly mixed. The present officinal formula is as follows : Fluid Extract of Rose, . . 10 parts or 2 fl. ounces. Syrup, 90 parts or 14 fl. ounces. Mix them. This is used for coloring and flavoring. The Br. P. directs 2 ounces av. of dried Red Rose Petals to be infused for 2 hours in 20 fl. ounces of Water, then pressed and the liquid heated to boiling, filtered, and 30 ounces of Sugar dissolved in the filtrate. 3160. Syrupus Rubi. Syrup of Rubus {Blackberry). Fluid Extract of Rubus (Blackberry), . 4 fl.ounces. Syrup, 12 fl.ounces. Mix them. The fluid extract designated is made from Blackberry Root. A Syrup of Blackberry for flavoring Soda Water and for other purposes is also made from the fruit. This is used as an astringent for diarrhoea, etc. Dose a tea- spoonful or more. SYRUPI — SYRUPS. 815 3161. Syrupus Rubi Idaei. Syrup of Raspberry. The U. S. P. formula is as follows: Fresh ripe Raspberries, any convenient quantity. Sugar, a sufficient quantity. Reduce the Raspberries to a pulp and let it stand at rest for three days. Separate the juice by pressing and set it aside until it has completely fermented and become clear, and then filter. To each pint of the filtered juice then add 25 ounces av. of Sugar, heat to boiling, avoiding the use of tinned vessels, and strain. Keep the Syrup in well-stopped bottles in a cool, dark place. The G. P. formula is about the same. This is evidently given as a representative formula for Fruit Syrups, and although it makes a good Syrup it does not retain the natural flavor of the fruit as does a Syrup made from the juice without being fermented. See formulas for Fruit Syrups. 3162. Syrupus Sarsaparilla Compositus. Compound Syrup of Sarsaparilla. Sarsaparilla, .... 150 parts or 25 ounces av. Guaiacum Wood, . . 20 parts or T>/i ounces av. Pale Rose, .... 12 parts or 2 ounces av. Liquorice Root, . . 12 parts or 2 ounces av. Senna, 12 parts or 2 ounces av. Sassafras, 6 parts or 1 ounce av. Anise, 6 parts or 1 ounce av. Gaultheria, .... 6 parts or 1 ounce av. Sugar, 600 parts or 100 ounces av. Water, . . . ) each, sufficient to make Diluted Alcohol, I 1000 parts or about 7 pints. (The drugs should all be about No. 30 powder.) Mix the solid ingredients except the Sugar with three pints of Diluted Alcohol and macerate the mixture for forty-eight hours; then transfer it to a cylindrical percolator, pack it firmly, and gradually pour Diluted .Alcohol upon it until 6 pints of tincture have been obtained. Evaporate this portion, by means of a water-bath, to 3 pints, add a pint of Water, and filter, adding enough Water through tin- filter to make 4 pints. 816 SYRUPI — SYRUPS. Lastly, add the Sugar, dissolve it by agitation, without heat, and strain. U. S. 1880. Other formulas for Syrup Sarsaparilla Compound will be found among the Standard Remedies. MADE BY WATER-BATH PERCOLATION. Sarsaparilla, in No. 30 powder, . . 25 ounces av. Guaicum Wood, in No. 30 powder, 3 ounces av. Pale Rose, in No. 30 powder, . . 2 ounces av. Liquorice Root, in No. 30 powder, 2 ounces av. Senna, in No. 30 powder, .... 2 ounces av. Sassafras, in No. 30 powder, ... 1 ounce av. Anise, in No. 30 powder, . . . . 1 ounce av. Sarsaparilla Flavoring (see below), . y 2 fl. ounce. Sugar, in coarse powder, .... 6yi pounds av. Water, . . . ) „ . „.. . . , , , I each, a sufficient quantity. Diluted Alcohol, ) n ' Mix the solid ingredients, except the Sugar, and moisten them with \ l / 2 pints of Diluted Alcohol, set in a covered vessel in a warm place for 12 hours, then transfer to the water- bath percolator, pack moderately, pour upon them 2 pints of Diluted Alcohol and set in a warm place for 24 hours; then heat moderately, and after one hour begin to percolate, adding Diluted Alcohol to the drugs and continuing the heat and percolation until 6 pints of the tincture have passed. Distill off three pints of Alcohol, by means of the water-bath and still, add a pint of Water to the residue and filter, adding enough Water though the filter to make the measure 4 pints. Mix the Sarsaparilla Flavoring with 4 ounces of the Sugar and dissolve this with the remainder of the Sugar in the liquid by percolation or agitation. Sarsaparilla Flavoring, or Essence of Sarsaparilla, is the same as is used for flavoring Soda Water Syrups, and is made as follows : Oil of Wintergreen, 4 fl. drachms. Oil of Sassafras, 3 fl. drachms. Oil of Anise, 1 fl. drachm. Cologne Spirit, 12 fl. ounces. Water, 4 fl. ounces. SVRUPI — SYRUPS. 817 Mix, and, if necessary, filter through a little Carbonate of Magnesium. 3163. Syrupus Scillae. Syrup of Squill. The U. S. P. formula is as follows : Vinegar of Squill, ... 40 parts or 1 pint. Sugar, in coarse powder, . 60 parts or 26 ounces av. Water, sufficient to make 100 parts or 2 pints. Heat the Vinegar of Squill to the boiling point in a glass or porcelain vessel and filter while hot, adding enough Water through the filter to make the filtrate weigh 40 parts or mea- sure a pint ; add the Sugar, dissolve it by agitation, without heat, and strain. The Br. formula is about the same. This is used for coughs, in doses of J / 2 to a teaspoonful. 3164. Syrupus Scillae Compositus. Compound Syrup of Squill {Hive Syrup). The U. S. P. formula is : Squill, 120 parts or 2]/ 2 ounces av. Senega, 120 parts or 2]/ 2 ounces av. Tartrate of Antimony and Potassium, .... 3 parts or 28 grains. Sugar, 1200 parts or 26 ounces av. Precipitated Phosphate of Calcium, .... 9 parts or 90 grains. Diluted Alcohol, ) each sufficient to make Water, . . . 1 2000 parts or 2 pints. The drugs should be in No. 30 powder. Mix the Squill and Senega, and, having moistened the mix- ture with half a pint of Diluted Alcohol, macerate for an hour, then transfer the mixture to a conical percolator and gradually pour upon it Diluted Alcohol until one and a half pints of tincture are obtained. Boil this portion for a few minutes and then evaporate it by means of a water-bath to half a pint, having added three ounces of boiling Water, triturate the mixture with the precipitated Phosphate of Calcium, and add, 818 SYRUPI — SYRUPS. through the filter, enough warm Water to make the whole measure one pint. In this dissolve the Sugar by agitation, without heat, and strain. Lastly, dissolve the Tartrate of Antimony and Potassium in a fl. ounce of hot Water, and mix the solution thoroughly with the Syrup. U. S. 1880. MADE BY WATER-BATH PERCOLATION. Squill, in No. 20 powder, .... 2^ ounces av. Senega, in No. 30 powder, . . . 2^2 ounces av. Tartrate of Antimony and Potassium, 32 grains. Sugar, 28 ounces av. Diluted Alcohol, ( , „ . > each, sufficient. Water, . . . . ) Mix the Squill and Senega, moisten with 5 fl. ounces of Diluted Alcohol, and set in a covered vessel for 12 hours; then transfer to the water-bath percolator, pack very moder- ately, pour upon it a pint of Diluted Alcohol, and set in a warm place for 24 hours ; then heat very moderately, and after one hour, begin to percolate, adding Water to the drug and continuing the heat and percolation until a pint and a half of the percolate has passed. Distill off 12 fl. ounces of Alcohol, and boil the residue for 15 minutes; then evaporate it to half a pint and filter, adding enough Water through the filter to make 15 fl. ounces. In this dissolve the Sugar by percolation or agitation, and having dissolved the Tartrate of Antimony and Potassium in an ounce of hot Water, add to the Syrup and mix thoroughly. This is much used as a cough Syrup and emetic, in doses of ]/ 2 to a teaspoonful or more. 3165. Syrupus Senegae. Syrup of Senega — 1880. Syrup of Seneka — 1870. The U. S. P. 1880 formula is : Fluid Extract of Senega, . 160 parts or 8 fl. ounces. Water of Ammonia, . . 4 parts or 90 rrtinims. Sugar, in coarse powder, . 600 parts or 28 ounces av. Water, sufficient to make 1000 parts or 2 pints. Mix the Fluid Extract with 12 ounces of Water, add the Water of Ammonia, shake the mixture well, and let it stand SYRUPI — SYRUPS. 819 for a few hours ; then filter, adding enough Water through the filter to make ij fl. ounces. To the filtered solution add the Sugar and dissolve by agitation or percolation, without heat, and strain. This contains 16 per cent of Senega. The G. P. preparation contains only 5 per cent, of Senega. MADE BY WATER-BATH PERCOLATION. Senega, in No. 40 powder, ... 8 ounces av. Diluted Alcohol, 1 pint. Water of Ammonia, 1 % fl. drachm. Sugar, 28 ounces av. Water, a sufficient quantity. Moisten the drug with 8 fl.ounces of Diluted Alcohol and let stand for 12 hours, then pack moderately in the water-bath percolator; pour upon it the remainder (8 fl.ounces) of the Diluted Alcohol and set in a warm place for one day; then heat very moderately, and after one hour begin to percolate, adding Water to the drug, and continuing the heat and perco- lation until a pint of the tincture has passed ; boil this for 15 minutes to coagulate the albumen and starchy matter, continue the evaporation by gentle heat until the liquid is reduced to half a pint, and filter through muslin, without pressure, adding a little Water through the filter to preserve the measure. To the filtered liquid add 8 ounces of Water and the Water of Ammonia, and, after standing 3 or 4 hours, filter through paper and dissolve the Sugar in the filtrate by agitation or percolation. This is a tonic expectorant much esteemed in cough mix- tures. Dose ]/ 2 to 1 fl. drachm. 3166. Syrupus Sennae. Syrup of Senna. The U. S. P. 1880 formula is: Senna, bruised, . . . . 33 parts or 16 ounces av. Sugar, in coarse powder, . 60 parts or 29 ounces av. Alcohol, 4 parts or 2 fl.ounces. Oil of Coriander, ... 8 minims. Water, a sufficient quantity. 820 SYRUPI — SYRUPS. Digest the Senna in five pints of Water, at a temperature not exceeding 50 C. (122 F.), for 24 hours, express and strain the liquid ; digest the mass with 2 pints of Water, at the same temperature, for 24 hours, express and strain as before, mix the strained liquids and evaporate the mixture to 15 fl. ounces. When cold add the Alcohol, previously mixed with the Oil of Coriander, and filter through paper, adding, through the filter, enough Water to make the whole measure 17 fl. ounces. Then add the Sugar, dissolve it by agitation or percolation, and strain. As this Syrup is about one-half the strength of the Fluid Extract, it .seems an unnecessary officinal. It may be made extemporaneously by mixing equal measure of Fluid Extract of Senna and Syrup. It may also be made by water-bath percolation. The Br. P. formula is about the same. The G. P. prepara- tion contains only 10 per cent, of Senna. The dose as a laxa- tive is 1 to 4 fl. drachms. 3167. Syrupus Tolutanus. Syrup of To I u. As the U. S. P. 1870 formula for Syrup of Tolu is generally preferred, both that and the 1880 formula are given. U. S. P. 1870 FORMULA. Tincture of Tolu (U. S. 1870), . . 2 fl. ounces. Carbonate of Magnesium, .... 120 grains. Sugar, in coarse powder, .... 28^ ounces av. Water, 1 pint. Rub the Tincture of Tolu first with the Carbonate of Mag- nesium and 2 ounces of the Sugar, and then with the Water, gradually added, and filter. To the filtered liquid add the re- mainder of the Sugar, and, having dissolved it with the aid of a gentle heat, strain the solution while hot. U. S. P. 1880 FORMULA. Balsam of Tolu, .... 4 parts or 1^ ounces av. Sugar, in coarse powder, . 65 parts or 28 ounces av. Distilled Water, a sufficient quantity. SYRUPI — SYRUPS. 821 Mix the Sugar with 13 fl. ounces of Distilled Water, add the Balsam- and digest the whole in a covered vessel, at a tempera- ture not exceeding 82 C. (180 F.), for 2 hours. When cold, strain through a well-wetted muslin strainer, adding enough Water through the strainer to make the Syrup measure 2 pints, and mix thoroughly. The formula of 1870 is much to be preferred, both on ac- count of the manner of making and the quality and appear- ance of the finished Syrup. The Br. P. formula is about the same as the U. S. 1880. 3168. Syrupus Zingiberis. Syrup of Ginger. As the Syrup of Ginger of the U. S. P. 1870 and 1880 differ considerably, both formulas are given, the 1870 formula being generally preferred. U. S. P. 1870 FORMULA. Fluid Extract of Ginger, .... 3 fl. drachms. Carbonate of Magnesium, .... 60 grains. Sugar, in coarse powder, .... 26 ounces av. Water, I pint. Rub the Fluid Extract of Ginger with the Carbonate of Magnesium and 2 ounces of the Sugar, and then with the Water, gradually added, and filter. To the filtrate add the remainder of the Sugar, and, having dissolved it with the aid of gentle heat, strain the solution while hot. U. S. P. 1880. Fluid Extract of Ginger, . 2 parts or 1 fl. ounce. Sugar, in coarse powder, . 65 parts or 30 ounces av. Water, a sufficient quantity. Rub the Fluid Extract of Ginger with 12 ounces of Sugar and expose the mixture to a heat not exceeding 6o° C. (140 F.) until all the Alcohol has evaporated. Then mix the resi- due thoroughly by agitation with 15 ounces of Water and filter the liquid, adding through the filter enough Water to make the whole measure 22 fl. ounces. Finally, add the remainder of the Sugar, dissolve it by agitation, without heat, and filter. 822 SYRUPI — SYRUPS. As with Syrup of Tolu, the 1880 formula is no improvement over the 1870, in fact makes a much less desirable preparation and takes more time and trouble. The 1870 formula may be made without the use of heat, by percolation or agitation. The Br. P. formula is strong Tincture of Ginger 6 fl. drachms, Syrup 19 fl. ounces. This is used as a stimulant and stomachic, in doses of I or 2 fl. drachms. Unofficial Syrups. Besides the foregoing syrups official in the U. S., Br. and German Pharmacopoeias, a great many which are not official are much used. These include the syrups of vegetable sub- stances which are popular or convenient ; the syrups of chemical substances, which are mostly included in the prepara- tions of elegant pharmacy; syrups used for soda water and other beverages, and a great variety of other syrups which have been introduced into pharmacy and medicine, because of their value, utility or application. The following are those most used : Syrups of Vegetable Substances. These syrups are arranged in classes according to their methods of preparation, medicinal strength, etc. 3169. Syrup Adiantum or Maiden Hair. Maiden Hair Fern 1 ounce av. Boiling Water, 10 fl. ounces. Sugar, 17 ounces av. Pour the Boiling Water on the drug and infuse for half an hour, then strain, and dissolve the Sugar in 9 fl.ourices of the liquid. This is used for coughs, etc.; the dose being from a teaspoonful to a tablespoonful. It is also known as Syrup Capillaire. It may be flavored with orange flower or other aromatic water. 3170. Syrup Carrageen or Iceland Moss. — Soak first in Water, and pour off to deprive of bitterness. Then make as above. 3171. Syrup Corsican Moss, or Helminthocortus. Make as above. 3172. Syrup Liquorice Root, or Glycyrrhiza, and of other similar sub- stances which make demulcent syrups are prepared in the same manner. SYRUPI — SYRUPS. 3173. Syrup Aniseed. Aniseed in coarse powder 2 ounces av. Boiling Water 12 fl.ounces. Sugar 17 ounces av. Pour the boiling Water on the drug and infuse by gentle heat in a covered vessel for two hours, then strain and in 10 fl.ounces of the strained infusion dissolve the Sugar. This is a representative of a great number of aromatic syrups that may be made from seeds, fruit, and other substances. The following Syrups are made in the same manner : 3174. Syrup Caraway or Carum. 3175. Syrup Cardamom or Cardamomum. 3176. Syrup Cloves or Carophylles. 3177. Syrup Coltsfoot or Tussilagino. 3178. Syrup Cubeb or Cubebae. 3179. Syrup Eucalyptus, Eucalyptus Globulus. 3180. Syrup Fennel or Foeniculum. 3181. Syrup Gillinia. 3182. Syrup Hyssop or Hyssopus. 3183. Syrup Juniper Berries. 3184. Syrup Sweet Flag or Calamus. 3185. Syrup Violets. — Fresh flowers 8 ounces ; dried, 2 ounces. 3186. Syrup Anthemis. Syrup of Chamojnile. Chamomile Flowers 1 ounce av. Boiling Water, 12 fl.ounces. Sugar 17 ounces av. Pour the Boiling Water upon the drug and infuse for two hours in a covered vessel, then strain and in 9 fl.ounces of the strained infusion, dissolve the sugar. This is representative of a great many syrups that may be prepared from herbs, flowers, leaves, roots, barks, etc. The following syrups may be prepared in a similar manner : 3187. Syrup Bark or Chinchona. 3188. Syrup Bayberry Bark. 3189. Syrup Blackberry Root or Rubus. 3190. Syrup Bloodroot or Sanguinaria. 3191. Syrup Colchicum. 3192. Syrup Dulcamara or Bitter Sweet. 3193. Syrup Calls or Nutgalls. 3194. Syrup Hoarhound or Marrubium. 3195. Syrup Jalap. 3196. Syrup Lobelia. 824 SYRUPI — SYRUPS. 3197. Syrup Pipsissewa or Chimaphila. 3198. Syrup Saffron. 3199. Syrup Valerian. 3200. Syrup Vanilla, and many others. 3201. Syrup Asparagus. Asparagus Juice, clarified, 9 fl. ounces. Sugar, 17 fl.ounces. The juice is first clarified by heating almost to boiling and straining. The Sugar is then dissolved in 9 flounces of the clarified juice by gentle heat. Other syrups are prepared from fresh juices of succulent plants in a similar manner. The following are made in this manner : 3202. Syrup Fumitory. 3203. Syrup Hounds Tongue. 3204. Syrup Hedge Mustard. 3205. Syrup Symphytic. — Comfrey Juice and Plantain Juice each equal parts with Sugar, as above. 3206. Syrup Asafetida. Asafetida, in powder 1 ounce av. Carbonate of Magnesium, 6 drachms. Boiling Water, 10 fl.ounces. Essence of Peppermn: 1 1 fl.ounce. Sugar, 16 ounces av. Rub the Asafetida with the Carbonate of Magnesium in a mortar and add the Boiling Water ; when cool add the Essence of Peppermint, filter, adding water enough through the filter to make 9 fl.ounces, and dissolve the Sugar in the filtrate by agitation. Other syrups may be prepared from gum-resins, balsams, etc., in the same manner, omitting the Essence of Peppermint. 3207. Syrup Ammoniac. 3208. Syrup Balsam Peru. 3209. Syrup Benzoin. 3210. Syrup Canada Balsam. 321 1. Syrup Copaiba. 3212. Syrup Guaiacum. 3213. Syrup Liquidambar or Sweet Gum. 3214. Syrup Belladonna. Fluid Extract Belladonna 1 fl.ounce. Water, 8 fl.ounces. Sugar 17 ounces av. Mix the fluid extract with the water, filter and dissolve the Sugar in the filtrate. SYRUPI — SYRUPS. 825 This is representative of a great many syrups that may readily be made from fluid extracts in this manner, such as : 3215 Syrup Digitalis or Foxglove. 3216. Syrup Guarana or Paulinia?. 3217. Syrup Hydrastis or Golden Seal. 3218. Syrup Hyoscyamus or Henbane. 3219. Syrup Stramonium or Datura, and many others of similar strength and character. Syrups may be made from less active drugs by taking Fluid Extract of Drug, 2 fl.ounces. Water, 7 fl.ounces. Sugar 17 ounces av. and making a syrup in the same manner as the foregoing. 3220. Syrup Opium. Aqueous Extract of Opium 128 grains. Water, warm 9 fl.ounces. Sugar 17 ounces av. Rub the extract with the water until dissolved, filter and dissolve the Sugar in the filtrate. Dose, from half to a teaspoonful. Many other syrups of Extracts may be made in the same manner, using such a quantity of the extract that a teaspoonful will contain the ordinary dose of the medicine. The following are examples : 3221. Syrup Conium, 128 grains extract in a pint. 3222. Syru Coca or Erythroxylon 1 ounce extract in a pint. 3223. Syrup Euonymus yi ounce extract in a pint. 3224. Syrup Liquorice Extract, 1 ounce extract in a pint. 3225. Syrup Taraxacum or Dandelion, 2 ounces extract in a pint. Many others may be made in a similar manner. 3226. Syrup Svapnia. Svapnia 128 grains. Hot Water 9 fl.ounces. Sugar 17 ounces av. Rub the Svapnia to a fine powder and dissolve in the Hot Water, filter the solution and dissolve the Sugar in the filtrate. Dose, a half to a teaspoonful. Svapnia is a proprietary preparation of purified opium made by evapor- ating a purified solution of opium and pouring upon glass. It is used for the same purposes as Opium. SVRUPI — SYRUPS. Compound Vegetable Syrups. The following are the principal unofficial Compound Vegetable Syrups : 3227. Antiscrobutic Syrup. — Scurvygrass, Watercresses, Horseradish, fresh, of each, 10 ounces ; Buckbean 1 ounce, Bitter Orange 2 ounces, Cinnamon ]/ z ounce, White Wine 45 fl.ounces. Macerate 2 days, then distill off 10 ounces av. and add to the distillate 25 ounces av. of Sugar. Strain the residue left after distilling, clarify with White of Egg, and add to the syrup prepared from the distillate. Dose, 2 to 4 drachms. 3228. Syrup Aralia Compound — Alterative Syrup. — This may be made by mixing Fluid Extract Spikenard Compound (1615), . . . . 4 fl.ounces. Syrup 12 fl.ounces. or by making an extract of the ingredients as directed (161 5), distilling off the Alcohol and making 4 pints of syrup with Sugar and Water. This is the Eclectic Syrup Aralia or Spikenard Compound, much esteemed as an alterative. The dose is from a teaspoonful to a tablespoonful. 3229. Syrup Artemisia Compound — Syrup of Mugwort Compound. — Fresh tops of Mugwort, Pennyroyal, Catnip and Savine, each 2 ounces av. ; fresh roots of Elecampane, Lovage, and Fennel, each 88 grains ; fresh tops of Marjoram, Hyssop, Rue, Feverfew, and Basil, of each 1 ounce av. ; Aniseed % ounce, Cinnamon X ounce, Rectified Spirit 3 ounces, Water 30 ounces, Syrup of Honey 12^ ounces av. Infuse the plants with the Water and spirit, and after standing 24 hours distill over 4 fl.ounces, press the residue, clarify the liquid with White of Egg, add Sugar, 25 ounces av., make into a syrup, add the Syrup of Honey, and lastly the distilled liquid, and strain. The dose is 2 to 8 drachms as an aromatic tonic and bitter. 3230. Syrup Asarum Compound. — Macerate i]4 ounce av. of-Asarum (Canada Snakeroot or Wild Ginger), with 10 fl.ounces of Diluted Alcohol. Pour off the liquid and reserve. Then add 4 fl.ounces of Water, macerate and express, adding the liquid to the portion reserved. To this add 40 grains Cochineal in powder, 75 grains Carbonate of Potassium, Wine of Ipecae 1 fl.ounce, and 28 ounces of Sugar, dissolve and strain. This is used in cough mixtures, and as a fine aromatic. Dose, a teaspoonful or more. 3231. Syrup Blackberry Aromatic. — This syrup may be made by mixing: Fluid Extract of Blackberry Aromatic (1 581), .' . . 2 fl.ounces. Syrup, 14 fl.ounces. Or by making an extract of the ingredients as directed (161 5), distilling off the Alcohol and making 1 gallon of syrup with Sugar and Water. It may also be made by adding 2 fl.ounces of Fluid Extract of Blackberry and % ounce Fluid Extract of Aromatics to 14 fl.ounces of syrup. 3232. Syrup Carrageen Compound — Compotmd Syrup of Iceland Moss. — Pour Cold Water on l A ounce of Iceland Moss and let stand 12 hours, SYRUPI — SYRUPS. 827 then pour off and throw away. Boil Hoarhound yi ounce, Liverwort y 2 ounce and the softened Carrageen with i pint of Water for 20 minutes or more, then strain 12 fl. ounces and dissolve in the liquid 24 ounces av. of Sugar. This is an excellent demulcent cough syrup. Dose, a teaspoonful or more. 3233. Syrup Ceanothus Compound — Compound Syrup of Red-root. — Tops and leaves of Red-root or Ceanothus, Wild Lettuce, each 1 ounce av. ; Cimicifuga y z ounce, Pleurisy Root, Wild Ginger Root, each % ounce ; Lobelia, Bloodroot, each 1 drachm. Make an extract with Diluted Alcohol, distill off the Alcohol and make 2 pints of syrup with the residue, Sugar and Water. This is used as a cough remedy. The dose is a teaspoonful or more. 3234. Syrup Corydalis Compound. Compound Syrup of Turkey Corn. Turkey-corn Tubers, 10 ounces av. Twin Leaf (Jeffersonia Diphylla), 5 ounces av. Blue Flag, 2^ ounces av. Sheep Laurel Leaves, i l / 2 ounces av. Sugar, 6 pounds av. Alcohol, Water, each sufficient. Reduce the drugs to a coarse powder and cover them with Alcohol. Macerate for 24 hours, then put in the water-bath percolator. Draw off the Alcoholic tincture, and reserve. Continue the percolation with Water until exhausted. Evaporate the last portion of the percolate to a thin extract, add the reserved percolate and enough Water to make the measure 5 pints, after standing, filter, and dissolve the Sugar in the filtrate by percolation or very gentle heat. This syrup is much esteemed by the Eclectics as an alterative and diuretic for scrofula, syphilis, etc. The dose is a teaspoonful or more. 3235. Syrup Liquorice Compound. Compound Syrup of Glycyrrhiza. Liquorice Root, in coarse powder, 2 pounds av. Marshmellow Root, cut 8 ounces av. Sugar ' 6 pounds av. Alcohol, Water, each sufficient. Ma< crate the drugs with Warm Water enough to cover them well, pouring off the liquid after standing a few hours, and repeating the operation until one gallon is obtained, evaporate to 4 pints, strain, add one pint of Alcohol, and dissolve the Sugar in the liquid by percolation or gentle heat. This is an excellent demulcent syrup for coughs, etc., and a vehicle for quinine without any objectionable qualities. 828 SYRUPI — SYRUPS. 3236. Syrup Marrubium Compound. Compound Syrup of Hoarhound — Pulmonary Syrup. This may be made by mixing 3 fl.ounces of Fluid Extract of Hoarhound Compound ( 1 597). with 6 fl.ounces of Water, filtering and dissolving in the filtrate 14 ounces av. of Sugar, or by making an extract from the drugs directed for making the fluid extract (1597), and making with it, by the addition of Sugar and Water, 5 ]/ 2 pints of Syrup. This is an excellent tonic cough syrup for pulmonary affections. The dose is a teaspoonful. 3237. Syrup Mitchella Compound. Compound Syrup of Partridgeberry or Squaw Vine — Mother's Cordial. This may be made by mixing y/ z fl.ounces of Fluid Extract Mitchella Compound (1605) with 6 fl.ounces of Water, filtering and dissolving in the filtrate 14 ounces av. of Sugar, or by making an extract of the drugs as directed in the formula (1605), and by the addition of Water and Sugar, making 5 pints of syrup. This syrup is an Eclectic preparation much esteemed as a parturient and uterine tonic. The dose is a teaspoonful to a tablespoonful. 3238. Syrup Opium and Ipecac. Dover s Syrup. This may be prepared in several ways, all amounting to the same. The following are the most expedient : Fluid Extract of Ipecac 128 minims. Aqueous Extract of Opium 75 grains. Syrup • . . 1 pint. Rub the Extract of Opium with the fluid extract and a portion of the syrup until dissolved, then add the remainder of the syrup. Or by mixing Deodorized Tincture of Opium 2^ fl.ounces. Fluid Extract Ipecac 128 minims. Syrup, sufficient to make 1 pint. This syrup contains the equivalent of 10 grains of Dover's Powder in a teaspoonful or fl. drachm, the usual dose. 3239. Syrup Phytolacca Compound. Co77ipound Syrup of Poke. This may be made by mixing 3 fl.ounces Fluid Extract of Poke Compound (1607) with 6 fl.ounces of Water, filtering and dissolving 14 ounces av. of Sugar in the filtrate, or by making an extract of the drugs directed (1607), and with Water and Sugar making 5>£ pints of syrup. This is an Eclectic Syrup used as an alterative. The dose is a teaspoonful or more. SYRUPI — SYRUPS. 3240. Syrup Rhubarb and Potassium. Neidralizi7ig Cordial. Rhubarb in very coarse powder 5 ounces av. Bicarbonate of Potassium 5 ounces av. Golden Seal, in coarse powder 2 ounces av. Cinnamon, in fine powder 2 ounces av. Oil of Peppermint, 30 minims. Alcohol, 1% pint. Sugar, 6 pounds av. Water, a sufficient quantity. Pack the drugs loosely in the water-bath percolator and having mixed the Alcohol with a pint and a half of Water, pour enough of the liquid on them to saturate and cover them. Let stand for 24 hours, and having dis- solved the Bicarbonate of Potassium in the remainder of the liquid pour it upon the drugs ; heat very moderately, and after an hour begin to percolate, reserving all that will pass. Remove the heat and continue the percolation with water until the drugs are exhausted. Evaporate this latter portion to iy 2 pints. Dissolve the Oil of Peppermint in the portion first reserved, add the evaporated portion and enough Water to make 5 pints, filter and dissolve the Sugar in the filtrate. This is a valuable Eclectic preparation, much used for dyspepsia and acid stomach. The dose is a teaspoonful to a tablespoonful. 3241. Syrup Rumex Compound. Compound Syrup of Yellow Dock — Scrofulous Syrup. This may be made by mixing 5 fl. ounces Fluid Extract Rumex Com- pound (1610) with 5 fl. ounces of Water, filtering and dissolving in the filtrate 14 ounces av. of Sugar. Or by making an extract of the drugs directed (1610), and with Water and Sugar making 4 pints of syrup. This is an Eclectic syrup much esteemed as a blood-purifier, alterative, etc. The dose is a teaspoonful to a tablespoonful. Iodide of Potassium may be added 1 or 2 drachms in a pint, if desired. 3242. Syrup Stillingia Compound. Compound Syrup of Queen's Root. This may be prepared by mixing 4 flounces of Fluid Extract of Stillingia •Compound (161 7) with 5 fl. ounces of Water, filtering and dissolving in the filtrate 14 ounces av. of Sugar, or by making an extract from the drugs directed (1617) and with Water and Sugar making 4 pints of syrup. This is a valuable alterative syrup and blood-purifier first introduced by ilu- " Eclectics." It is much more effective than Syrup Sarsaparilla Com- pound, and is given in scrofula, syphilis, etc. The dose is a teaspoonful to a .tablespoonful. Iodide of Potassium may be added if desired. 830 SYRUPI — SYRUPS. 3243. Syrup Yerba Santa Compound or Aromatic. Verba Santa, coarsely ground, 4 ounces av. Orange Peel, in coarse powder ]/ z ounce av. Cinnamon, in powder, 60 grains. Cloves, in powder 60 grains. Magnesia, Calcined % ounce av. Sugar 28 ounces av. Alcohol, { . . - . ,,- . c of each sufficient to make 2 pints. Water, * v Mix one part of Alcohol by measure with 7 parts of Water. Mix the drugs with the Magnesia, moisten with sufficient of the mixed Water and Alcohol and pack in the water-bath percolator, cover with the menstruum and allow to stand 24 hours. Then heat very moderately and begin to percolate, adding the menstruum and continuing the percolation until a pint is obtained, filter this, adding a little more magnesia to the filter if necessary to make clear, and dissolve the Sugar in the filtrate by gentle heat or by percolation. This syrup is one of the best known vehicles for quinine, as it almost entirely masks its bitterness. It may also be used for bronchial affections. Syrups of Chemical Substances. The following are unofficial syrups prepared from chemical substances, for which there is a demand in this country, most of them being known as elegant pharmaceutical preparations. They are, therefore, given more prominence than other un- official syrups. A great number used in French pharmacy cannot be mentioned here. 3244. Flavored Syrup. For making syrups of chemical substances as well as for other uses, a flavored simple syrup, which may be used in the same manner as the official simple syrup, is desirable. The following will be found suitable for this purpose : Elixir Flavoring (508), I fl. ounce. Carbonate of Magnesium, .... y 2 ounce av. Water, 4 pints. Sugar, 8 pounds av. Rub the Elixir Flavoring with the Carbonate of Magnesium in a mortar, add about one-third of the Water gradually, and SYRUPI — SYRUPS. 831 rub them well together ; add the mixture to the remainder of the Water, and after standing a day or two, filter and dissolve the Sugar in the filtrate, by percolation or agitation. 3245. Syrup Bromide of Iron (Tasteless.) Besides the official syrup Bromide of Iron (3134) a so-called tasteless syrup is made as follows : Bromide of Iron, 384 grains. Citrate of Potassium, \y 2 ounce av. Soluble Flavoring (510), .... 1 fl. ounce. Water, 7 fl. ounces. Sugar, 16 ounces av. Dissolve the Citrate of Potassium in the Water, add the Bromide of Iron and then the Soluble Flavoring, and filter. Dissolve the Sugar in the filtrate. A fl. drachm contains 3 grains Bromide of Iron. Dose 20 to 60 minims. 3246. Syrup Bromide of Morphine. Bromide of Morphine, 16 grains. Flavored Syrup, 1 pint. Dissolve the Morphine in y£ ounce of Warm Water, and add to the syrup. A fl. drachm contains )/% grain Bromide of Morphine. Dose a teaspoonful. 3247. Syrup Bromide of Quinine. Bromide of Quinine, 128 grains. Water 8 fl. ounces. Soluble Flavoring (5 10), I fl. ounce. Sugar, 16 ounces av. Dissolve the Bromide of Quinine in the Water by the aid of heat, add the Flavoring, and dissolve the Sugar in the solution. A fl. drachm contains 1 grain Bromide of Quinine. Dose, a teaspoonful. 832 SYRUPI— SYRUPS. 3248. Syrup Bromide of Quinine and Morphine. Bromide of Morphine, 16 grains. Syrup Bromide of Quinine (3247), . . 16 fl. ounces. Dissolve the Bromide of Morphine in ^ ounce of Hot Water and add to the syrup. A fl. drachm contains 1 grain Bromide of Quinine, ]/z grain Bromide of Morphine. Dose, a teaspoonful. 3249. Syrup Bromide of Quinine, Mor- phine, and Strychnine. Bromide of Morphine, 16 grains. Solution of Strychnine (1942), .... 2 fl. drachms. Syrup Bromide of Quinine (3247), ... 1 pint. Dissolve the Morphine Salt in % ounce of Hot Water, and add the solution with the Solution of Strychnine to the syrup. A fl. drachm contains 1 grain Bromide of Quinine, ]/% grain Bromide of Morphine, and -^ grain Strychnine. Dose, a teaspoonful. 3250. Syrup Bromide of Strychnine. Bromide of Strychnine, 4 grains. Flavored Syrup, 1 pint. Dissolve the Strychnine in ^2 fl. ounce of Boiling Water and add to the syrup. A fl. drachm contains ^ grain of the Strychnine Salt. Dose, a teaspoonful. 3251. Syrup Bromide of Strychnine and Morphine. Bromide of Strychnine, 4 grains. Bromide of Morphine, 16 grains. Flavored Syrup, 1 pint. Dissolve the Bromides in y 2 fl. ounce of Boiling Water and add to the syrup. A fl. drachm contains ¥ ^ grain Strychnine and l /% grain Mor- phine Bromides. Dose, a teaspoonful. SYRUPI — SYRUPS. 833 3252. Syrup Bromide Strychnine, Iron and Quinine. Bromide of Strychnine, 2 grains. Bromide of Quinine, 128 grains. Bromide of Iron 256 grains. Citrate of Potassium, 1 ounce. Soluble Flavoring, 1 fl. ounce. Water, 7 fl. ounces. Sugar, 16 ounces av. Dissolve the Citrate of Potassium in the Water, add the Iron Salt, then the Bromides, and dissolve by gentle heat, then add the Flavoring and Sugar. A fl. drachm represents -2 grains Bromide of Iron, I grain Bromide of Quinine and ^ grain Bromide of Strychnine. Dose, a teaspoonful. 3253. Syrup Bromide of Sodium. Bromide of Sodium 640 grains. Soluble Flavoring, . • 1 fl. ounce. Water, 8 fl. ounces. Sugar, 16 ounces av. Dissolve the Salt in the Water, add the flavoring and dis- solve the Sugar in the solution. A fl. drachm contains 5 grains of the Sodium Salt. Dose, a teaspoonful to a tablespoonful. Syrups of other Bromides, as Syrup Bromide of Potassium, Syrup Bromide of Ammonium, etc., may be made in the same proportion and manner. 3254. Syrup Citrate of Iron. Citrate of Iron and Ammonium, . . 256 grains. Hot Water I fl. ounce. Flavored Syrup 15 fl. ounces. Dissolve the Iron Salt in the Water, and add to the Syrup. A fl. drachm contains 2 grains of the Iron salt. The dose is a teaspoonful or two. 834 SYRU PI — SYRUPS. 3255. Syrup Citrate of Iron and Quinine. Citrate of Iron and Quinine 256 grains. Hot Water, 1 fl. ounce. Flavored Syrup, sufficient to make . . 1 pint. Dissolve the Salt in the Water, and add to the Syrup. A fl. drachm contains 2 grains Citrate of Iron and Quinine. The dose is a teaspoonful. 3256. Syrup Citrate of Iron, Quinine and Strychnine. Solution of Strychnine (1942), . . . . 1 fl. drachm. Syrup Citrate of Iron and Quinine (3255), 1 pint. Mix them thoroughly. A fl. drachm contains 2 grains Iron and Quinine and y^-g- grain Strychnine. The dose is a tea- spoonful. 3257. Syrup Citrate of Iron and Strychnine. Citrate of Iron and Strychnine, . . . 256 grains. Hot Water, 1 fl. ounce. Flavored Syrup, 1 pint. Dissolve the Salt in the Hot Water and add the Syrup. A fl. drachm contains 2 grains of the Iron and Strychnine Citrate. Dose, a teaspoonful. 3258. Syrup Hypophosphite of Calcium (Lime). Hypophosphite of Calcium, .... 384 grains. Water, 8 fl. ounces. Soluble Flavoring, 1 fl. ounce. Sugar, 16 fl. ounces. Rub the Salt to a powder and triturate in a mortar with the Water until dissolved, add the Soluble Flavoring, filter, and dissolve the Sugar in the filtrate without heat. A fl. drachm contains 3 grains Hypophosphite of Calcium. The dose is a teaspoonful to a dessertspoonful. SYRUPI — SYRUPS. 835 3259. Syrup Hypophosphite of Calcium and Sodium. Syrup HypopJwsphites of Lime and Soda. Hypophosphite of Calcium, 384 grains. Hypophosphite of Sodium 256. grains. Water, 8 fl. ounces. Soluble Flavoring, I fl. ounce. Sugar, 16 ounces av. Rub the salts to a fine powder and dissolve by rubbing with the Water, add the Flavoring and filter, then dissolve the Sugar in the filtrate without heat. A fl. drachm contains 5 grains of the Hypophosphites. The dose is a teaspoonful to a dessertspoonful. 3260. Syrup Hypophosphite of Calcium, Sodium, and Potassium. Syrup Hypophosphites Lime, Soda, and Potassa — Compound Syr tip of HypopJwsphites. Hypophosphite of Calcium, 256 grains. Hypophosphite of Sodium, 128 grains. Hypophosphite of Potassium, .... 64 grains. Water, 8 fl. ounces. Soluble Flavoring, I fl. ounce. Sugar, 16 ounces av. Rub the salts to a fine powder and then with the Water until dissolved ; add the Flavoring, filter, and dissolve the Sugar in the filtrate without heat. 3261. Syrup Hypophosphites of Calcium, Sodium, Potassium, and Iron. Syrup Hypophosphite Lime, Soda, Potassa, and Iron. Solution Hypophosphite of Iron (1928), 1 fl. ounce. Syrup Hypophosphites Compound (3260), 15 11. ounces. .Mix then). A ll. drachm contains about 4^ grains of Hypo- phosphites. The dose is a teaspoonful to a dessertspoonful. 836 SYRUPI — SYRUPS. 3262. Syrup Hypophosphite of Iron. Solution Hypophosphite of Iron (1928), 1 fl. ounce. Flavored Syrup, 15 fl. ounces. Mix them. A fl. drachm contains 1 grain Hypophosphite of Iron. Dose, a teaspoonful or more. 3263. Syrup Hypophosphite of Iron and Calcium. Solution Hypophosphite of Iron (1928), 1 fl. ounce. Syrup Hypophosphite of Calcium (3258), 15 fl. ounces. Mix them. A fl. drachm contains 1 grain of Iron and about 3 grains of Calcium Hypophosphite. Dose, a teaspoonful or more. 3264. Syrup Hypophosphite of Iron and Manganese. Solution Hypophosphite of Iron (1928), I fl. ounce. Solution Hypophosphite of Manganese (1929), 1 fl. ounce. Flavored Syrup, 14 fl. ounces. Mix them. A fl. drachm contains 1 grain each of the Hypo- phosphites. The dose is a teaspoonful or more. 3265. Syrup Hypophosphite of Manganese. Solution Hypophosphite of Manganese (1929), 1 fl. ounce. Flavored Syrup, 15 fl. ounces. Mix them. A fl. drachm contains 1 grain of Hypophosphite of Manganese. The dose is a teaspoonful or a dessertspoonful. 3266. Syrup Hypophosphite of Sodium. Syrup HypopJiosphitc of Soda. Hypophosphite of Sodium, 256 grains. Hot Water, 1 fl. ounce. Flavored Syrup, 15 fl. ounces. SYRUPI — SYRUPS. 837 Dissolve the Salt in the hot Water, strain, and mix the solu- tion with the Syrup. A fl. drachm contains 2 grains Hypophosphite of Sodium. The dose is a dessertspoonful or more. 3267. Syrup Hypophosphites Compound with Quinine and Strychnine. This combination has of late become very popular as a nutritive tonic, and has, to a large extent, taken the place of other compound Syrups of Hypophosphites. Hypophosphite of Calcium, ... 4 ounces av. Hypophosphite of Sodium, ... 2 ounces av. Hypophosphite of Potassium, . . y^ ounce av. Hypophosphite of Manganese, . . % ounce av. Phosphate of Iron, in scales (1880), . I ounce av. Sulphate of Strychnine 8 grains. Sulphate of Quinine, y 2 ounce av. Citric Acid, 40 grains. Salicylic Acid, 10 grains. Sugar, 7 pounds av. Water, sufficient to make 1 gallon. Dissolve the Citric Acid in 8 fl. ounces of Water, and rub the Strychnine in a mortar with the solution until dissolved, then add the Quinine and Salicylic Acid to the solution, and, having transferred to a bottle, add 3 pints more of Water. Rub the Hypophosphites to a fine powder and add to the solution in the bottle. Dissolve the Phosphate of Iron in 8 fl. ounces of hot water, and add to the solution in the bottle. When all the salts are dissolved, filter the solution and dissolve the Sugar in the filtrate, making up the measure to 1 gallon with Water. If desired this may be flavored with 4 fl. ounces of Soluble Flavoring, but as found in the market it is usually without flavor. This is similar in composition to the proprietary Fellows' Syrup of Hypophosphites Compound. The dose is a teaspoonful to a dessertspoonful. A fl. drachm contains about 4 grains of the mixed Hypophosphites. 838 SYRUPI — SYRUPS. 3268. Syrup Hypophosphites Compound, with Lactopeptine. Syrup Hypophosphites Compound (3260), 12 fl. ounces. Lactopeptine, 256 grains. Hypophosphorous Acid I fl. ounce. Water. 3 fl. ounces. Rub the Lactopeptine with the Water, add the Acid and heat gently by water-bath until dissolved, strain the solution and add to the Syrup, mixing them thoroughly. 3269. Syrup Hypophosphites Compound, Iron, Quinine, and Strychnine. Quinine (Alkaloid), 60 grains. Strychnine (Alkaloid), 1 grain. Solution Hypophosphite of Iron (1928^. . 1 fl. ounce. Hypophosphorous Acid, 2 fl. drachms. Flavored Syrup, 15 fl. ounces. Dissolve the Quinine and Strychnine in the Hypophosphor- ous Acid by very gentle heat and add to the Syrup, then add the Iron Solution. A fl. drachm contains y 2 grain of Quinine, 1 grain Iron, and y^-g grain Strychnine. The dose is a teaspoonful to a dessert- spoonful. 3270. Syrup Iodide of Calcium. Syrup Iodide of Lime. Iodide of Calcium (Lime\ ...... 256 grains. Warm W^ater, I fl. ounce. Flavored Syrup, 15 fl. ounces. Dissolve the Calcium Iodide by rubbing with the Water and add the solution to the flavored Syrup. A fl. drachm contains 2 grains Iodide of Calcium. This Syrup is given as an alterative in doses of a teaspoonful or more. SYRUPI — SYRUPS. 839 3271. Syrup Iodide of Iron (Tasteless). Tasteless Iodide of Iron, 256 grains. Warm Water, I fl. ounce. Flavored Syrup, 15 fl. ounces. Rub the Iodide with the Water and add the solution to the Syrup. A fl. drachm contains 2 grains of the Tasteless Iodide of Iron. This is given as a tonic and resolvent in doses of a tea- spoonful or more. It has not the disagreeable taste of the official Syrup Iodide of Iron. 3272. Syrup Iodide of Iron and Manganese. Iodide of Iron (tasteless), 128 grains. Iodide of Manganese, 128 grains. Warm Water, 1 fl. ounce. Flavored Syrup, 15 fl. ounces. Rub the Iodides with the Water and add the solution to the Syrup. A fl. drachm contains 1 grain each Iodide of Iron and Man- ganese. The dose is a teaspoonful as a tonic and alterative. 3273. Syrup Iodide of Manganese. Iodide of Manganese, 256 grains. Warm Water, t fl. ounce. Flavored Syrup, 15 fl. ounces. Dissolve the Iodide by rubbing with the Water, and add the solution to the Syrup. A fl. drachm contains 2 grains Iodide of Manganese. The dose is a teaspoonful, as a tonic. 3274. Syrup Iodide. of Starch. Iodide of Starch, 16 grains. Flavored Syrup 1 11. ounce. Rub them well together. Id this the Iodide of Starch Is suspended in the Syrup, and it should be shaken when taken or dispensed. A colorless syrup 840 ' SYRUPI — SYRUPS. may be made by adding 128 grains Hyposulphite of Sodium, but this produces a Syrup of Iodide of Sodium instead. The Syrup Iodide of Starch may be given in doses of 1 to 4 fl. drachms. 3275. Syrup of Iron and Sodium Albuminate. " Nitrogenized Irony Chloride of Iron (the salt), 128 grains. Glycerin, 8 fl. ounces. Albumen (white of egg), 6 fl. ounces. Solution of Soda (1915), q. s., about . . 2 fl. ounces. Mix part of the Glycerin with the White of Egg and dis- solve the Iron by gentle heat in the remainder ; add the solu- tion of Iron thus prepared to the mixture of Glycerin and Albumen, stirring them well together for an hour or two, and forming a semi-solid gelatinous mass ; then add the Solution of Soda gradually, and with constant stirring, until the mass is dissolved and the solution is neutral. Allow to stand a few hours for the froth to subside, then pour off and strain. In making this preparation it is necessary to have it neutral, which may be determined by testing with litmus paper. If not entirely liquid after standing a few hours it will be neces- sary to add a little more Solution of Soda. This preparation has a bland, sweet taste and a bright color. It is an excellent iron tonic and nutritive, given in doses of a teaspoonful to a tablespoonful, a fl. drachm containing 1 grain of the Iron salt. 3276. Syrup Dialysed Iron. Solution Dialysed Iron (504), .... 640 minims. Flavored Syrup, enough to make ... 1 pint. Mix them. A fl. drachm contains 5 minims Solution Dia- lysed Iron. The dose is a teaspoonful to a dessertspoonful. 3277. Syrup Lactate of Iron. Solution Protoxide of Iron (1940), . . 1 fl. ounce. Lactic Acid, . . 90 minims. Flavored Syrup, 15 fl. ounces. Mix them. A fl. drachm contains I crrain Lactate of Iron. SYRUPI — SYRUPS. 841 3278. Syrup Lactophosphate of Calcium (Lime). Solution Lactophosphate of Calcium (1931), 2 fl. ounces. Flavored Syrup, 14 fl. ounces. Mix them. (See also 3129). A fl. drachm contains 2 grains Lactophosphate of Calcium. The dose is a teaspoonful to a dessertspoonful. 3279. Syrup Lactophosphate of Iron. Solution Lactophosphate of Iron (1932), 1 fl. ounce. Flavored Syrup, 15 fl. ounces. Mix them. A fl. drachm contains 1 grain Lactophosphate of Iron. The dose is a teaspoonful as a tonic. 3280. Syrup Lactophosphate of Iron and Calcium (Lime). Solution Lactophosphate of Iron (.1932), . y 2 fl. ounce. Solution Lactophosphate of Calcium (193 1), 1 fl. ounce. Flavored Syrup, 14^ fl. ounces. Mix them. A fl. drachm contains y 2 grain Iron and 1 grain Calcium Lactophosphates. The dose is a teaspoonful or more. 3281. Syrup Lactophosphate of Calcium and Pepsin. Syrup Lactophosphate of Calcium (3278), 8 fl. ounces. Syrup Pepsin (3288), 8 fl. ounces. Mix them. A fl. drachm contains about 1 grain Lactophos- phate of Calcium and 2 grains Pepsin. The dose is a tea- spoonful to a dessertspoon ful. 3282. Syrup Lactophosphate of Manganese. Solution Lactophosphate of Manganese (1933), 1 fl. ounce. Flavored Syrup, 15 fl. ounces. Mix them. A fl. drachm contains 1 grain Lactophosphate of Manganese. The dose is a teaspoonful to a dessertspoonful as a tonic. 842 SYRUPI — SYRUPS. 3283. Syrup Lactophosphates Compound. Syrup LactopJwspJiate Calcium, Iron and Manganese. Solution Lactophosphate of Iron (1932), . y 2 fl. ounce. Solution Lactophosphate of Calcium (1935), 1 fl. ounce. Solution Lactophosphate of Manganese (1933), y 2 fl. ounce. Flavored Syrup, 14 fl. ounces. Mix them. A fl. drachm contains x / 2 grain each Lactophos- phate of Iron and Manganese, and 1 grain Lactophosphate of Calcium. Dose, a teaspoonful to a dessertspoonful as a tonic. 3284. Syrup Lactopeptine. Lactopeptine, 384 grains. Hydrochloric Acid, i^fl. drachm. Water, 8 fl. ounces. Soluble Flavoring, 1 fl. ounce. Sugar, 14 fl. ounces. Macerate the Lactopeptine in the mixed liquids for 24 hours, with occasional agitation, then strain, and dissolve the Sugar in the liquid. A fl. drachm contains 3 grains Lactopeptine. The dose is a teaspoonful or more. 3285. Syrup Lactopeptine Compound. Solution Phosphate of Iron (1935), . 1 fl. ounce. Solution Phosphate of Calcium (1936), 1 fl. ounce. Phosphate of Sodium, 128 grains. Phosphate of Potassium 128 grains. Hydrochloric Acid i^fl. drachm. Lactopeptine, 256 grains. Water, 6% fl.ounces. Soluble Flavoring 1 fl. ounce. Sugar, 14 fl.ounces. Rub the Lactopeptine and the salts together; mix the solu- tions, add the Acid and Water, and add the powders to the SYRUPI — SYRUPS. • 843 mixture. Macerate for 24 hours, and strain, add the flavoring and dissolve the Sugar in the liquid. The dose is a teaspoon- ful to a dessertspoonful. 3286. Syrup Morphine. This may be made with either the Acetate, Hydrochlorate, SulpJiate, or other soluble salt of Morphine, as follows : The Morphine Salt, 16 grains. Hot Water, 2 fl. drachms. Flavored Syrup, I pint. Dissolve the Morphine Salt in the Hot Water and add to the Syrup. A fl. drachm contains y% grain of the salt. The usual dose is a teaspoonful, as an anodyne. 3287. Syrup Muriate of Ammonia. Syrup Chloride of Ammonium. Chloride of Ammonium in powder, . . 640 grains. Water, 8 fl. ounces. Soluble Flavoring, 1 fl. ounce. Sugar, 16 ounces av. Dissolve the salt in the Water, filter, add the Flavoring and dissolve the Sugar in the liquid. A fl. drachm contains 5 grains of the salt. The dose is a teaspoonful or more. 3288. Syrup Pepsin. Saccharated Pepsin, 1 ounce av. Hydrochloric Acid, 1 fl. drachm. Water, 8 fl. ounces. Soluble Flavoring, i fl. ounce. Sugar, 16 ounces av. Rub the Pepsin with the Water and add the Acid, let stand until dissolved, strain, add the Flavoring, and dissolve the Sugar in the liquid without heat. A fl. drachm contains 31^ grains Saccharated Pepsin. The dose is a teaspoonful to a dessertspoonful. 844 SYRUPI — SYRUPS. 3289. Syrup Nascent Phenic Acid. Pure Phenic or Carbolic Acid, .... 67 grains. Glycerin, 1 fl. ounce. Flavored Syrup, 15 fl. ounces. Rub the Acid with the Glycerin in a mortar until dissolved, and add to the Syrup. This is somewhat heavier and of a different flavor than the Syrup Pure Nascent Phenic Acid prepared by Declat Manufac- turing Co., New-York, but contains the same quantity of the acid. If desired like this, use double the quantity of Glycerin with 1 ounce of Water and plain Syrup, flavoring with Essence of Cognac, I fl. drachm. The dose is a tablespoonful. 3290. Syrup Phosphate of Calcium. • Syrup Phosphate of Lime. Solution Phosphate of Calcium (1935), . 2 fl. ounces. Flavored Syrup, 14 fl. ounces. Mix them. A fl. drachm contains 2 grains Phosphate of Lime. The dose is a teaspoonful to a dessertspoonful. 3291. Syrup Phosphate of Iron. Solution Phosphate of Iron (1936), . i 1 /^ fl. ounces. Flavored Syrup, 14^ fl. ounces. Mix them. This may also be prepared by dissolving 384 grains of Phosphate of Iron (the scale salt) in a fl. ounce of boiling Water and adding to 14.% fl. ounces of Flavored Syrup. A fl. drachm contains 3 grains of Phosphate of Iron. The dose is a teaspoonful or more. See also 3137. 3292. Syrup Phosphate of Manganese. Solution Phosphate of Manganese (1937), 1 fl. ounce. Flavored Syrup, 15 fl. ounces. Mix them. A fl. drachm contains 1 grain Phosphate of Man- ganese. The dose is 1 or 2 teaspoonfuls, as a tonic. SYRUPI — SYRUPS. 845 3293. Syrup Phosphate of Manganese Compound. Solution Phosphate of Iron (1936), . ]/ 2 fl. ounce. Solution Phosphate of Manganese (1937), 1 fl. ounce. Phosphate of Sodium, 128 grains. Flavored Syrup, 14 fl. ounces. Dissolve the Sodium Salt in half an ounce of hot Water and add to the Syrup, then add the solutions and mix. A fl. drachm contains I grain each Iron, Manganese, and Sodium Phosphates. Dose, a teaspoonful or two, as a tonic. 3294. Syrup Phosphates Compound. Chemical Food. Solution Phosphates Compound (1938), 2 fl. ounces. Flavored Syrup, 14 fl. ounces. Mix and color with Red Coloring (442). The dose is a tea- spoonful or two, as a tonic and vitalizer. A fl. drachm contains about 3^ grains of the mixed Phos- phates in solution, with excess of Phosphoric Acid. This Syrup has been a very popular preparation. The formula above given is the most convenient, as the solution has only to be mixed with the Syrup, the tedious process which was formerly used being avoided. As some may wish to prepare this after the old method the formula is here given. The following solutions are first made: Sulphate of Iron 1 jounces. Phosphate of Sodium 1 $ ounces. Dissolve the Iron salt in half gallon hot Water, and mix with 1 gallon Water in an earthen crock or other suitable vessel for precipitating. Dis- solve the Sodium salt in half gallon hot Water, and add the Solution of Iron to it in the jar. Agitate thoroughly and allow to stand a few hours for the precipitate to subside, l'our off the Water, and pour upon the precipitate 1 gallon of fresh Water. Agitate, allow to stand as before, pour off the Water, and pour the precipitate upon a cloth strainer to drain. (The object of using the large amount of Water in the precipitating jar is to dissolve the Sulphate of Sodium as soon as formed, and save the troublesome washing of 846 SYRUPI — SYRUPS. the precipitate usually adopted.) As soon as the precipitate is drained, mix it with Water, 2 flounces. Sugar 1 ounce av. Hydrochloric Acid 6 fl. drachms. and dissolve. This makes a Solution of Phosphate of Iron with Hydrochloric Acid. Then take of Phosphate of Calcium (Lime) 1280 grains. Hydrochloric Acid, q. s., or 4 ounces. Hot Water, 4 ounces. Mix the Phosphate of Lime with the hot Water, and add enough Hydro- chloric Acid to dissolve. (The amount depends upon the strength of the Acid.) This makes a Solution of Phosphate of Lime with Hydrochloric Acid. Then, to make the Syrup, take the Solution Phosphate of Iron, as above. The Solution Phosphate of Calcium (Lime), ... as above. Diluted Phosphoric Acid 5 ounces. Extract Vanilla 1 ounce. Cochineal, powdered y z ounce. Phosphate of Sodium 160 grains. Phosphate of Potassium 80 grains. Water, enough to make 3 pints. Sugar, ...'...■ 4>£ pounds av. Mix the Solutions of Iron and Calcium, and add the Phosphoric Acid. Dissolve the Phosphate of Sodium and Potassium in a little hot Water, and add to the Solutions. Add the Vanilla and Cochineal, and then Water enough to make the measure 3 pints. Allow to stand a few hours, to get the color from the Cochineal, etc., and filter. Dissolve the Sugar in the filtrate, and strain if necessary. This makes a beautiful permanent Syrup. Each fl. drachm contains 2 grains Phosphate of Calcium, 1 grain Phosphate Iron, with fractions of a grain of Phosphate of Sodium and Potassium, and an excess of Acid. The Hydrochloric Acid in it is not objectionable and makes the preparation permanent. 3295. Syrup Phosphate of Quinine. Sulphate of Quinine, 128 grains. Phosphoric Acid, diluted, y 2 fl. ounce. Flavored Syrup, 1 pint. Dissolve the Quinine Salt in the Acid and add the Syrup. A fl. drachm contains 1 grain of the Quinine Salt. SYRUPI — SYRUPS. 847 3296. Syrup Phosphate of Quinine and Iron. Sulphate of Quinine, 128 grains. Phosphoric Acid, diluted, y 2 fl. ounce. Solution Phosphate of Iron (1936), . ]/ 2 fl. ounce. Flavored Syrup, 15 fl. ounces. Dissolve the Quinine Salt in the Acid and add to the Syrup, mix, then add the. Iron Solution. A fl. drachm contains 1 grain each Iron and Quinine. 3297. Syrup Phosphate of Quinine, Iron and Strychnine. Syrup Phosphate of Quinine and Iron (3296), 1 pint. Solution of Strychnine (1942), 2 fl. drachms. Add the Strychnine Solution to the Syrup and mix them thoroughly. A fl. drachm contains I grain each Quinine and Iron and -^ grain Strychnine. See also the official Syrup (3138). This Syrup is known and often prescribed as Syrup Triple Phosphates. 3298. Syrup Protoxide of Iron. Solution Protoxide of Iron, 1 fl. ounce. Flavored Syrup, 15 fl.ounces. Mix them. A fl. drachm contains 1 grain Protocitrate of Iron. The dose is a dessertspoonful or more. 3299. Syrup Pyrophosphate of Iron. The Syrups of Pyrophosphate of Iron and combinations for which formula have been given in previous issues of FENNER'S FORMULARY are not here repeated, for the reason that much more stable preparations may be made with the new Phos- phate of Iron salt in scales of the U. S., 1880, Pharmacopoeia. If desired, they may be made by adding Solution of Pyro- phosphate of Iron, double the quantity as is directed of the Phosphate to neutral Syrups. Syrup Pyrophosphate of Iron may be made by adding 2 ll. ounces of the Solution to 14 fl.ounces of the Syrup. 848 SODA WATER SYRUPS. Soda Water Syrups. A great variety of Syrups are used by those who dispense Soda Water, for flavoring and sweetening the gaseous water. Simple Syrup is used as a base and the flavoring ingredients added. The flavoring consists of natural fruit juices, or vari- ous solutions of oils or aromatic substances, ethers, etc., which are mixed with the Syrup. As these solutions are variously made and are of different strength as prepared by different manufacturers, definite for- mulas cannot be given for any except those flavorings which are mentioned in this volume. It will, therefore, be under- stood that in the formulas given it is expected that the flavor- ings designated will be such as are made after the formulas which are referred to — which may be either prepared as directed or purchased of the Fenner Medicine Co. 3300. Syrup for Soda Water. As a basis for the Syrups used for Soda Water a simple Syrup of good body and quality, to which the flavoring ingredients are to be added, may be made by druggists as follows : Gelatin, Cooper's or Cox's ^ ounce av. Water, 1 gallon. Sugar, best white 10 pounds av. Soak the Gelatin in a pint of Water for half an hour, then dissolve it by the heat of a water-bath, and, while hot, strain into the remainder of the Water through a coarse muslin strainer, stir thoroughly, add the Sugar, stir until dissolved, strain and set away in a cool place. The Syrup should be made of Crushed, Granulated, or "A" Coffee Sugar, and the best water that can be conveniently obtained. It should be made in well-tinned or zinced cans, or stone crocks ; a wooden vessel of any kind imparts its peculiar flavor to Syrup after standing, and rapidly develops the " acetic " change. The Syrup is best made by putting the proper amount of water in a can or crock, adding the sugar a portion at a time, and stirring with a stick until dissolved. A cover should be fitted to the can or crock, and a stopcock can be placed at the bottom, or a dipper may be hung on the inside always ready for use. Syrup should not be made up in any large quantity (no more than enough to last a week or ten days), and should always be made by the cold process. Many druggists buy for this purpose the Double Refitted Rock Candy Syrup made by Dryden & Palmer, of Baltimore, Md., or other similar Syrup. SODA WATER SYRUPS. 849 As this has no ingredients in it to make it " hold its foam " when the water is drawn into it, " Soda Foam " must be added either to the simple Syrup or when made up and flavored, the most convenient way being to add it to the simple Syrup which is then all ready for use. This may be done by dissolv- ing y/ 2 ounces av. of Gelatin in 2 quarts of Water and adding to 10 gallons of the Syrup, while hot, or by adding the proper quantity of the prepared Soda Foam. (3301.) 3301. Soda Foam. If the Syrup used for Soda Water is prepared as directed (3300) no other Foam will be necessary, but if the boughten Syrup is used it is necessary to add something to make it retain its Foam. Gelatin may be used as directed, but it is sometimes convenient to have a liquid Foam which may be added to the Syrups as made up by the gallon. For this purpose the following for- mulas may be used : Soap Bark (Ouillaya. ground) 1 pound av. Alcohol, 8 fl. ounces. Water, a sufficient quantity. Cover the Soap Bark, in a porcelain-lined vessel, with boiling Water and infuse for 1 hour, then pour off the liquid and reserve. Pour fresh boiling Water on the Bark and again infuse, and pour off as before, repeating the operation three times; mix the decoctions obtained, and evaporate to \ l / 2 pint ; to this, when cool, add the Alcohol, and, after standing, filter. Add 1 ounce of this to a gallon of Syrup to make it foam. Acid Syrups require a larger quantity. A still better Foam, because it is nearly tasteless, may be prepared from Soaproot, a species of California lily-bulb, using the same proportions and making in the same manner as the foregoing. 3302. Fruit Acid. Citric Acid 4 ounces av. Hot Water 8 flounces. Dissolve the Acid in the Water. This is used for giving an acid or sour taste to Syrups, thereby making many of them more palatable. A more concentrated solution like 1927 is more desirable, but the formula here given is of the same strength as is generally prepared and used. _ The quantity to be used is usually stated in the formula, but may be regulated to suit the taste. 3303. Fruit Juice Syrups. For making; Fruit Syrups from juices a-- prepared (302S) it is only neces- sary to mix the juices 1 part by measure with 5 parts by measure <>f Syrup (3300). If they are desired of Stronger flavor mix one part of Juice with 4 parts of Syrup. 850 SODA WATER SYRUPS. Fruit Syrups may also be made from the freshly expressed juices by dis- solving in them all the Sugar they take when made by the cold process, which is about 14 pounds to each gallon of juice. Syrups made from Fruit Juices are infinitely superior to any which can be made from artificial extracts. The following Fruit Syrups may be made from Fenner's Fruit Juices in the manner above described, by mixing 1 measure of the Fruit Juice with 5 measures of Syrup : Syrup Apricot, Syrup Mulberry, Syrup Banana, Syrup Orange, Syrup Blackberry, Syrup Peach, Syrup Cherry, Black, Syrup Pear, Syrup Cherry, Red, Syrup Pineapple, Syrup Currant, Red, Syrup Plum or Prune, Syrup Grape, Syrup Quince, Syrup Huckleberry. Syrup Raspberry, Black, Syrup Lemon, Syrup Raspberry, Red, Syrup Lime, Syrup Strawberry. 3304. Ambrosia Syrup. Raspberry Juice 1 pint. Pineapple Juice 1 pint. Vanilla Extract, 1 fl.ounce. Syrup, sufficient to make 1 gallon. This is a rich, finely-flavored Fruit Syrup. Other Fruit Juices besides those mentioned may be used. 3305- Apple Syrup. Apple Essence (958) y z fl.ounce. Cider, sweet, 1 pint. Fruit Acid 14 fl.ounce. Syrup, sufficient to make 1 gallon. If sweet or bottled Cider is not readily at hand use 1 fl.ounce of the Essence of Apple, and omit it. 3306. Apricot Syrup. Apricot Juice 1 pint. Syrup 2 pints. An inferior Syrup may be made with Apricot Essence (958) 1 fl.ounce. Fruit Acid y z fl.ounce. Syrup 1 gallon. SODA WATER SYRUPS. 851 3307. Banana Syrup. Banana Juice 1 pint. Fruit Acid l / z fl.ounce. Syrup, 5 pints. Mix them. An inferior Syrup may be made with Banana Essence (959) 1 fl.ounce. Fruit Acid >£ fl.ounce. Syrup, 1 gallon. 3308. Birch Beer Syrup. Birch Beer Extract (952) 3 fl.ounces. Fruit Acid J^ fl.ounce. Syrup 1 gallon. Mix and color with Caramel. 3309. Ottawa Beer Syrup, from Ottawa Beer Extract (953). 3310. Peruvian Beer Syrup, from Peruvian Beer Extract (954). 331 1. Root Beer Syrup, from Root Beer Extract (955). 3312. Spruce Beer Syrup, from Spruce Beer Extract (956). And others similar may be made in the same proportion and manner as Birch Beer Syrup. Unless the business in Soda Water is quite large, it is much the best way to have these in the form of Syrup as above, and draw the plain Soda Water upon them the same as any other syrups. 3313. Blackberry Syrup. Blackberry Juice 1 pint. Fruit Acid X fl.ounce. Syrup 5 pints. Mix them. An inferior Syrup may be made with Blackberry Essence (960) 1 fl.ounce. Fruit Acid, >< fl.ounce. Syrup 1 gallon. This may be colored with Caramel and Red Coloring. 3314. Brandy Syrup. ic Essence % fl.ounce. I '.randy 2 pints. Fruit Acid 2 iLdrachm^ Syrup 6 pints. Mix them. 852 SODA WATER SYRUPS. Other Liquor Syrups may be prepared with other liquors in a similar man- ner, using the desired spirits and the essences of the kind required. Bour- bon and Rye Whisky, Rum, and other liquors are made into syrups in this way. They are usually sold under some fancy name. 3315. Calamus Syrup. Calamus Essence (894) 2 fl.ounces. Syrup 1 gallon. Mix them. 3316. Calisaya Syrup. Sulphate of Quinine 10 grains. Sulphate of Cinchonidine 30 grains. Fruit Acid 2 fi. drachms. Syrup 1 gallon. Dissolve the salts in the Acid and 1 ounce of Water, and mix with the Syrup. Color red with Red Coloring. 3317. Calisaya Phosphate Syrup. Fenner's Calisaya Phosphate 1 pint. Syrup 7 pints. Mix them. This is an excellent tonic, the valuable properties of Calisaya Bark being combined with Phosphates Compound. 3318. Caraway Syrup. Caraway Essence (895), 2 fl.ounces. Syrup, 1 gallon. Mix them. 3319. Catawba Syrup. Catawba Grape Juice 1 pint. Brandy }i pint. Syrup, 5 pints. Mix them. An inferior Syrup may be made with Catawba Grape Essence (965) . . . 1 fl. ounce. Fruit Acid 1 fl. ounce. Syrup 1 gallon. Other varieties of Grape Syrup may be made in the same manner by using other grape juices. SODA WATER SYRUPS. 853 3320. Champagne Syrup. Rhine Wine, 3 pints. Pear Essence (972) y 2 fl .ounce. Syrup 5 pints. Mix them. 3321. Cherry Syrup, Red or Black. Cherry Juice. Red or Black 1 pint. Syrup 5 pints. Mix them. Made from true Cherry Juice, these Syrups are excellent. Inferior Syrups may be made from the artificial extracts, as follows : Black or Red Cherry Essence (961 or 978) 1 flounce. Fruit Acid 1 fl. ounce. Syrup 1 gallon. Mix them. 3322. Cherry Phosphate Syrup. Concentrated Solution Phosphates (1938), 1 flounce. Cherry Juice 1 pint. Syrup 5 pints. Mix them. This may be flavored stronger by adding % fl. ounce Cherry Essence (961.) It is a popular drink at the fountain. 3323. Wild Cherry Syrup. Fluid Extract Wild Cherry 8 fl. ounces. " Syrup 1 gallon. Or, Wild Cherry Essence (981) 2 fl. ounces. Syrup 1 gallon. Mix them. 3324. Chocolate Syrup. lemur's Perfection Cream Chocolate 1 pint. Syrup 3 pints. Mix them. The Perfection Chocolate (ream mentioned is a liquid emulsion of Choco- late, made by grinding the finest Chocolate with Cum Syrups and Flavoring Extracts through a mill specially constru ted for the purpose. It mixes with 854 SODA WATER SYRUPS. Syrup without separation, and can be drawn like any other Syrup from the fountain. To make it successfully requires expensive machinery. Ordinary Chocolate Syrup is made as follows : Chocolate, i cake or 8 ounces av. Vanilla Extract (940) 1 fl. ounce. Syrup, 3^ pints. Liquefy the Chocolate by a water-bath and gradually add the Syrup, stir- ring them well together until all is added, strain through a wire sieve, and, when nearly cold, add the Vanilla, mixing them well together. As thus made the Syrup separates from the Chocolate after standing, and the mixture must be shaken before using. 3325. Cinnamon Syrup. Cinnamon Essence (897), 1 fl. ounce. Syrup, 1 gallon. Mix them. 3326. Claret Syrup. Claret, 2 pints. Syrup, 4 pints. Mix them. 3327. Coffee Syrup. Coffee Extract (932) 8 fl.ounces. Syrup 1 gallon. Mix them. This Syrup depends upon the strength of the Coffee Extract used. It may be flavored to suit with any other good Extract of Coffee, or as follows : Java and Mocha Coffee, browned, each 4 ounces. Boiling Water, 4 pints. Make a decoction, strain and dissolve in the liquid 6 pounds of Sugar, and add Soda Foam 1 ounce. 3328. Cognac Syrup. Cognac Essence (902,) 1 flounce. Syrup 1 gallon. Mix them. This may be improved by the addition of half a pint of Brandy. SODA WATER SYRUPS. 855 3329. Cream Syrup. Sweet Milk, fresh, 1 quart. Corn Starch, y z ounce av. Egg. l Sugar, 1 y 2 pound av. Vanilla Extract, 1 fl. ounce. Salicylic Acid, 5 grains. Mix the Corn Starch with an ounce of Water, beat up the Egg thoroughly and mix them, then heat the Milk with the mixture to make a custard. When it has thickened, take off and add the Sugar and Salicylic Acid. When cool add the Vanilla Extract. As thus prepared this Syrup will keep for some time, but it is advisable to make it fresh every morning for use during the day. This Syrup should not be kept in the syrup cans but in a bottle on the ice. Many do not make a Cream Syrup at all, but keep cream in a bottle handy, which is added to the other Syrups as desired. Cream Syrup is seldom drawn alone, but is mixed with other Syrups, as Chocolate, Coffee, Vanilla, Strawberry, and, in fact, nearly all others. Some druggists have the leading Syrups prepared already with cream, but it is not advisable except for a very large business, as the cream or Cream Syrup may readily be added to any other Syrup. 3330. Curacoa Syrup. Curacoa Essence (904) 1 fl.ounce. Fruit Acid y z fl.ounce. Syrup 1 gallon. Mix them. This is similar to but of finer flavor than Orange. 3331. Currant Syrup, Red or Black. Currant Juice 1 pint. Syrup 5 pints. Mix them. An inferior Syrup may be made with Currant Essence, Black or Red (962, 979) 1 fl.ounce. Fruit Acid, 1 fl.ounce. Syrup 1 gallon. Mix them. 3332. Don't Care Syrup. Most any Syrup may be drawn when " Don't Care" is wanted. The fol- lowing is a general favorite : Wintergreen Essence, 1 ounce. Vanilla Extract .... 2 ounces. Syrup i gallon. Mix them. 856 SODA WATER SYRUPS. 3333- E &g Nogg Syrup, or Milk Punch Syrup. Brandy, Jamaica Rum, each, 4 ounces. Fresh Cream 1 pint. or Milk 1 quart. Eggs 2 Corn Starch 2 ounces. Extract Vanilla (940), 1 ounce. Syrup, 1 quart. Beat the Eggs and the Corn Starch, and add the Milk ; heat to a custard, stirring constantly ; when it thickens remove from the fire, cool, and add the Brandy, Rum, and Vanilla Flavoring. 3334. Ginger Syrup. Soluble Extract of Ginger (943) 4 rl. ounces. Fruit Acid ]A. fl.ounce. Syrup 1 gallon. Mix them. Other Extracts of Ginger which are not " soluble " may be used, but they do not make so good preparations. 3335- Ginger Ale Syrup. Ginger Ale Extract (944), 3 fl.ounces. Fruit Acid >£ fl.ounce. Syrup, 1 gallon. Mix them. This is the most convenient manner of drawing Ginger Ale, and gives as good satisfaction as when drawn from a separate fountain. 3336. Grape Syrup. Grape Juice 1 pint. Syrup, 5 pints. Mix them. Any kind of Grape Juice may be made up into a Syrup; half a pint of Brandy added improves the flavor. An inferier Syrup may be made with Grape Essence (965} 1 fl.ounce. Fruit Acid, . . . . 1 fl.ounce. Syrup, ... 1 gallon. 3337. Grape Phosphate Syrup. Solution Phosphates Concentrated (938), .... \% fl.ounce. Grape Juice 1 % pint. Syrup, sufficient to make 1 gallon. Mix them. This is a very popular Syrup. SODA WATER SYRUPS. 857 3338. Huckleberry Syrup. Huckleberry Juice, 1 pint. Fruit Acid, % fl.ounce. Syrup, 5 pints. Mix them. Blueberry Syrup, which is much the same, is made in the same manner. An inferior Syrup may be made with Blueberry Essence 1 fl.ounce. Fruit Acid, % fl.ounce. Syrup 1 gallon. 3339- H oc k Syrup. Hock Wine 2 pints. Syrup 6 pints. Mix them. 3340. Lemon Syrup. This is usually made with Lemon Essence (910) 1 fl.ounce. Fruit Acid \}4. fl.ounce. Syrup 1 gallon. If Lemon Juice is used for making the Syrup, take Lemon Juice, . * 1 pint. Lemon Essence (910) ^ fl.ounce. Syrup 5 pints. A clear Syrup of Lemon may be made by taking- Soluble Extract of Lemon (945) 3 fl. ounces. Fruit Acid, i}4. fl.ounce. or Lemon Juice 1 pint. Syrup 1 gallon. Lemon Syrup deteriorates rapidly, and the very best way to dispense it is to have a bottle of Lemon Essence, with a squirt top, a bottle of Lemon Juice, and plain Syrup ready at hand. The plain Syrup should be kept for this and other purposes in one of the Syrup cans. Draw the Syrup in the glass, add the Juice (some want it more acid than others), then the Essence, and draw the gaseous water upon it as usual. These same remarks apply also to Lime and Orange Syrups. 3341. Lemon Phosphate Syrup. Solution Phosphates Concentrated O93S) 2 B.ounces. Lemon Essence (910) 1 fl.ounce. Syrup 1 gallon. Mix them. 858 SODA WATER SYRUPS. 3342. Lime Fruit Syrup. Lime Juice 1 pint. Syrup, 5 pints. This Syrup is strongly acid, which is as usually wanted when Lime Syrup is ordered. It may be flavored more, if desired, by adding l / 2 flounce Lime Essence (91 1 ). It is most convenient to have a bottle of Lime Juice handy, and add to plain Syrup when wanted, as directed for Lemon Syrup. 3343. Lime Fruit Phosphate Syrup. Solution Phosphates Compound (1938) i fl. ounce. Lime Fruit Juice, 1 pint. Lime Essence (911), 1 flounce. Syrup, sufficient to make 1 gallon. 3344. Mace or Nutmeg Syrup. Mace or Nutmeg Essence (91 1 or 914), i}4. fl. ounce. Syrup, 1 gallon. Mix them. This makes a fine addition to some of the other Syrups, but is seldom used alone. 3345. Malt Tonic Syrup. Liquid Malt Extract, 1 pint. Syrup 5 pints. Mix them. 3346. Malt Hop Phosphate Syrup. Fenner's Malt Hop Phosphate, 1 pint. Syrup 7 pints. Mix them. This is an excellent tonic and restorative, and makes an attrac- tive drink at the fountain. 3347- Maple Syrup. Maple Syrup, with Soda Foam added, or Maple Sugar, y/ 2 pounds. Water, 1 quart. Dissolve by heat and add Soda Foam. 3348. Mulberry Syrup. Mulberry Juice • . . . . 1 pint. Syrup 5 pints. Mix them. SODA WATER SYRUPS. 859 3349. Nectar Syrup. Vanilla Extract (939) 2 fl.ounces. Pineapple Juice, 1 pint. Raspberry Juice 1 pint. Syrup, 1 gallon. Mix them. This may be made, also, as follows : Nectar Essence (968), 1 fi.ounce. Fruit Acid, yi fi.ounce. Syrup 1 gallon. 3350. Nectarine Syrup. Nectarine Essence (969), 1 fi.ounce. Fruit Acid, ]/ z fi.ounce. Syrup, 1 gallon. Mix them. This may also be made from Nectarine Fruit Juice when it can be obtained, in the same manner as other Fruit Syrups. 335 1 - Orange Syrup. Orange Essence (915) 1 fi.ounce. Fruit Acid %, fi.ounce. Syrup 1 gallon. If Orange Juice is used for making the Syrup, take Orange Juice 1 pint. Orange Essence (915) ^"fi.ounce. Syrup, 5 pints. It may be made, also, with Soluble Extract of Orange (948), 3 fl.ounces. Fruit Acid >£ fi.ounce. Syrup 1 gallon. This Syrup deteriorates by standing, and may best be dispensed as directed after Lemon Syrup. 3352. Orange Phosphate Syrup. Concentrated Solution Phosphates (1938), .... 2 fl.ounces. Orange Essence (915) i l / 2 fi.ounce. Syrup 1 gallon. Mix them. This is quite a popular beverage. SCO SODA WATER SYRUPS. 3353. Maltese Orange Syrup. Red Orange of Malta Syrup — Blood Orange Syrup. < >range Essence (915), 1% fl.ounce. Fruit Acid }4 fl.ounce. Syrup 1 gallon. Mix them, and color red with Cochineal Coloring. 3354. Orange Flower Syrup. Orange Flower Water, 1 pint. Syrup, 4 pints. This is sometimes added to other Syrups but is seldom dispensed alone. 3355. Orgeat Syrup. Orgeat Essence (970) 1 fl.ounce. Syrup 1 gallon. The plain Bitter Almond Syrup is frequently dispensed under this title. Bitter Almond Essence (893) 1 fl.ounce. Syrup 1 gallon. 3356. Peach Syrup. Peach Juice 1 pint. Syrup, 5 pints. An inferior Syrup may be made from Peach Essence (971) 1 fl.ounce. Fruit Acid l / 2 fl.ounce. Syrup 1 gallon. Mix them. 3357. Pear Syrup. Pear Juice 1 pint. Syrup 5 pints. A very good artificial Pear Syrup may be made with Pear Essence (972) 1 fl.ounce. Fruit Acid % fl.ounce. Syrup 1 gallon. Mix them. 3358. Pear Phosphate Syrup. Concentrated Solution Phosphates (1938) 2 fl.ounces. Pear Essence (972) 1 fl.ounce. Syrup 1 gallon. Mix them. This may also be made with Pear Juice 1 pint, Concentrated Solution Phosphates 1 ounce, Syrup 5 pints. SODA WATER SYRUPS. 861 3359. Phosphate Syrups. A great variety of Phosphate Syrups may be made by combining Concen- trated Solution of Phosphates Compound (1938) with various Fruit Syrups, etc. The principal ones have been mentioned under the heading of the Syrup with which the combinations are made. The Phosphate Syrups are much in demand and take well wherever introduced. 3360. Acid Phosphate Syrup. Concentrated Solution of Phosphates (1938), ... 2 flounces. Syrup 1 gallon. This may be flavored with any flavoring extract if desired, but for general use is best kept plain as an addition to other Syrups, with which it may be mixed equally. It can also be drawn and served with a dash of Lemon, Orange, or Lime Fruit Essence, as wanted. Another way, which is perhaps as good as any, is to mix i part of the Concentrated Solution with 4 parts of Water and add this from a "squirt " bottle to any desired Syrup to make the combination desired. This does away with the necessity of keeping a variety of Phosphate Syrups already made up. 3361. Pineapple Syrup. Pineapple Juice 1 pint. Fruit Acid, . y z fl. ounce. Syrup 5 pints. Mix them. An inferior Syrup of Pineapple may also be made with Pineapple Essence (973) 1 fl.ounce. Fruit Acid % fl.ounce. Syrup, 1 gallon. 3362. Pineapple Phosphate Syrup. Concentrated Solution Phosphates (1938) 1 fl.ounce. Pineapple Juice 1 pint. Syrup 5 pints. Mix them. 3363. Plum or Prune Syrup. Plum or Prune Juice 1 pint. Syrup 5 pints. Mix them. An inferior Syrup may be made from Plum or Prune Essence (974 or 975) [fl.ounce. Fruit Acid i fl.ounce. Syrup 1 gallon. 862 SODA WATER SYRUPS. 3364. Quince Syrup. Quince Juice , . . 1 pint. Fruit Acid V* fl.ounce. Syrup, 5 P»nts. Mix them. A very good imitation of Quince may be made with Quince Essence, 1 fl. ounce. Fruit Acid • ^fl.ounce. Syrup I gallon. 3365. Raspberry Syrup, Red or Black. Raspberry Juice, Red or Black 1 pint. Syrup 5 P ints - Mix them. The Red Raspberry Syrup is considered the finest flavor of any of the fruit syrups. Black Raspberry Syrup has a much different flavor and a very dark color. An inferior Syrup, imitating Raspberry, may be made with Raspberry Essence (977) 1 fl.ounce. Fruit Acid 1 fl.ounce. Syrup • 1 gallon. 3366. Raspberry Phosphate Syrup. Concentrated Solution Phosphates (1938) I fl.ounce. Raspberry Juice, 1 pint. Syrup, 5 P ints - Mix them. This is one of the finest flavored Phosphate Syrups. 3367. Rose Syrup. Rose Essence (920) 1 fl.ounce. Syrup 1 gallon. Mix them. Color light red with Red Coloring. 3368. Sarsaparilla Syrup. Sarsaparilla Essence (923) i}4 fl.ounce. Fruit Acid, %. fl.ounce. Syrup 1 gallon. Mix, and color brown with Caramel. This Syrup is improved by adding 1 drachm of Glycyrrhizin in scales, dis- solved in a little water. A perfectly clear Syrup may be made with Soluble Extract Sarsaparilla (949) 3 fl. ounces Fruit Acid Yz fl.ounce. Syrup 1 gallon. Color with Caramel. SODA WATER SYRUPS. 863 3369. Sherbet Syrup. Vanilla Extract (940) 1 fl.ounce. Pineapple Juice 1 pint. Lemon Extract, Soluble (945) 1 fl. ounce. Syrup, 5 pints. This may also be mixed extemporaneously from the fountain by drawing equal parts of Vanilla, Pineapple, and Lemon or Orange Syrups. This may be made also with Sherbet Extract (935) 1 fl. ounce. Syrup 1 gallon. 3370. Persian Sherbet. This is usually served by drawing into a glass sufficient Strawberry or Vanilla Syrup, then adding from " squirt " bottles a few drops each of Lemon Extract, Orange Extract, Fruit Acid, and drawing the water upon them, or, adding ice, drawing most full of water and shaking it with a shaker. Fancy sauce bottles for this purpose are supplied by dealers. The Fruit Acid will be white, the Lemon yellow, and the Orange should be col- ored a bright red. The manipulation of the drink is an attraction. 3371. Strawberry Syrup. Strawberry Juice, 1 pint. Syrup, 5 pints. Mix them. As the color is usually deficient in Strawberry Juice to satisfy the popular taste, it may be colored slightly with Red Coloring, or by the addition of a little Raspberry Juice, which also improves its flavor. An inferior Syrup may be made with Strawberry Essence (980) 1 fl .ounce. Fruit Acid, % fl.ounce. Syrup, 1 gallon. With Red Coloring sufficient. 3372. Strawberry Phosphate Syrup. Concentrated Solution Phosphates 11938) 1 fl.ounce. Strawberry Juice I pint. Syrup 5 pints. Mix them. This is the least desirable of the Fruit Phosphate Syrups. 3373. Tea Syrup. Green Tea, good quality 2 ounces av. Boiling Water 1 pint. Sugar 1 '4 pound av. Infuse the Tea in the boiling Water, strain, and add enough Water to make 1 pint, then dissolve the Sugar in the liquid and add a little Soda Foam. 864 SODA WATER SYRUPS. 3374. Vanilla Syrup. Vanilla Extract (940) i]/ z fl. ounces. Syrup 1 gallon. Mix them. Vanilla Syrup is one of the most popuhr soda-water syrups. It is com- bined with nearly all the other syrups, and drawn with cream is a great favorite. It is necessary that only a pure Vanilla Extract of fine flavor be used for making this Syrup. Inferior or mixed extracts will not draw custom. 3375. Violet Syrup. Orris Extract (934) 1 fl. ounce. Syrup 1 gallon. Mix them. This makes a fair imitation of Violet. A true Syrup of Violets may be made by gathering the violet flowers 'in their season, and macerating with Syrup. 3376. Wine Syrups. Wine of any kind 2 pints. Syrup 3 pints. Mix them. 3377. Wintergreen Syrup. Wintergreen Essence (927) \ l / 2 flounce. Syrup 1 gallon. Mix them. A perfectly clear Syrup may be made with Soluble Extract Wintergreen (951), 3 fl. ounces. Syrup 1 gallon. Mix them. Other Soda Water Syrups, etc. The foregoing are the regular syrups dispensed at soda fountains, many of them being also useful for other purposes. Besides these, several other drinks are served in various ways in connection with the fountain. 3378. Ice Cream Soda. This is prepared by drawing the desired Syrup into a glass, adding a large spoonful or more of Ice Cream without flavor, and drawing the gaseous Water upon it. A long-handled spoon is generally put in the glass with SODA WATER SYRUPS. 865 which to stir its contents and sip the beverage or eat the ice cream which rises to the surface; it is therefore frequently called " Spoon Soda." Any Syrup may be combined in this manner with the Ice Cream, and if properly served it is very nice. The Ice Cream should be liberally used. 3379. Milk Shake. This has become very popular, special apparatus being provided for shak- ing it. Ice is first shaved into a tumbler, milk is poured upon it until nearly full, it is then transferred to the shaker, agitated, and then poured back into the glass. The milk may be mixed with a small quantity of any flavored syrup if desired, but is generally preferred without sweetening or flavor. In absence of the patent shakers it may be shaken in the ordinary hand shaker usually at hand. A little soda water may be drawn into it to give it "sparkle." 3380. Milk Punch Shake. This may be made by shaving ice in a glass, adding the usual quantity of Vanilla or other flavored Syrup, drawing part full of Soda Water, then nearly filling with milk and adding, if desired, a little liquor — Brandy, Rum, Whisky, or Wine — then shaking on the patent shaker or with the hand shaker as directed above. Without the liquor, this may be dispensed as Temperance Punch. An egg added is a great improvement. 3381. Fruit Juice Shakes. Shake drinks may be made with any of the Fruit Juices, as follows. They are similar to lemonade or other ades, and give excellent satisfaction. Plenty of ice should be used : Any Fruit Juice 1 fl. ounce. Syrup of the same kind 2 fl. ounces. Shave ice in the tumbler and draw "solid" with Soda Water, transfer to the shaker and shake, or shake with hand shaker. A dash of Lemon Essence, Orange Essence, or Lime Fruit Essence, added to Lemon, Orange, or Lime Fruit Shakes adds to their flavor and makes an attraction. By squeezing the juice from fresh fruit into the glass the attrac- tiveness of the drink is much increased. 3382. Cobbler Shakes. These are made by mixing in a small, thin glass, Wine, any kind 2 ounces. Lime or Lemon Juice }& ounce. Lemon Syrup 2 ounces. Shaving ice in the glass, drawing solid with Soda Water, and shaking as before dire< ted. 866 SODA WATER SYRUPS. 3383. Cocktail Shakes. These are made by adding to ice shaven in a glass, Brandy, Rum, Whisky, or Gin about 1 y 2 ounce, Lime, Lemon, or Orange Juice yi ounce, Syrup 1 ounce, a dash of Stoughton Bitters, and then enough Soda Water to fill a small glass, and shaking as directed. 3384. Egg Phosphate Shake. Shave ice in a glass, add Lemon or other Fruit Syrup 2 ounces, a dash of Lemon Essence, the contents of 1 Egg, a dash of Acid Phosphate enough to make sour, draw Soda Water in the glass to nearly fill, and then shake as directed. Other similar drinks with Egg may be prepared in the same way. 3385. Nerve Foods and Tonics. Nerve Foods and Nerve Tonics have become very popular beverages at the soda fountain. "Acid Phosphate " is extensively used, the original " Horsfords" being used by many druggists, but most of them making or buying in bulk a concentrated solution of Phosphates Compound, which may be diluted or made into a syrup as directed. " Malto " is an acid beverage, used as a Nerve Tonic like Acid Phosphate. It is put up in bottles, sweetened and charged with gas, making a sparkling acid drink. A " Malto Syrup " is also made, which is to be diluted with 4 parts of Syrup and drawn from the fountain as any other syrup. The " Acid Phosphate Syrup " will answer the same purpose as this. " Moxie " Nerve Food is an entirely different preparation. The proprie- tary " Moxie " has had a large sale. A similar preparation for use at the fountain may be prepared and drawn as a syrup like any other syrup, as follows : Fluid Extract Sarsaparilla Compound 6 fl. ounces. Tincture of Gentian Compound 1 fl. ounce. Sarsaparilla Extract, Soluble (949) 3 fl. ounces. Concentrated Solution Phosphates, 2 fl. drachms. Syrup, to make 1 gallon. Mix them. For Mead, Ginger Ale, etc., see pages 422 to 427. Hot Soda Syrups. It is unnecessary to state that the so-called " Hot Soda Water," unlike the cold soda water, contains no gas, but the force is obtained from force of water, and heated in an apparatus specially designed for it. SODA WATER SYRUPS. 867 But comparatively few druggists who have fountains run hot soda water, as the demand is not sufficiently large to pay except in central locations in large towns. The syrups and drinks which are generally supplied are as follows : 3386. Chocolate Syrup. Fenner's Perfection Cream Chocolate. This is kept hot in a tank or bottle from which it can be drawn. A suffi- cient quantity, say 2 ounces, is poured or drawn in a cup, and the Hot Water drawn upon it. Milk or Cream is usually added before drawing the Water. Chocolate Syrup may also be made by melting on a water-bath Chocolate 1 pound, Vanilla Chocolate Yz pound together, and adding Hot Syrup 3 quarts, mixing them well together. 3387. Coffee Syrup. Coffee Extract (932), 1 pint. Syrup 3 pints. Keep this hot in a tank or bottle. It may be served with Cream or hot Milk added, or plain, drawing about 2 ounces of the Syrup in a cup and then drawing the hot W T ater upon it. 3388. Beef Tea Extract. Extract of Beef, Liebig's 4 ounces. Black Pepper, y 2 ounce. Hot Water 1 pint. Infuse the Pepper with the Water for half an hour and strain, then mix the Beef Extract with the liquid. To make Beef Tea pour a tablespoonful of this into a cup, add a little salt and draw hot Water upon it. 3389. Hot Lemonade. Lemon Juice, 1 ounce. Syrup, 1 ounce. Mix in a cup with a dash of Lemon Essence and draw hot Water upon it. A little liquor — Whisky, Brandy, or Rum — is sometimes added. Lime Juice may be used instead of Lemon. 3390. Hot Egg Phosphate. This is a shake drink, made by drawing Lemon Syrup, 2 ounces, in a glass, adding 1 Egg and a dash of Acid Phosphate, shake well together, and draw hot Water sufficient to make a glass of the beverage. The Water should not be too hot for this purpose. / 868 SODA WATER SYRUPS. Mineral Waters. It is most convenient to keep Solutions made up for the various artificial Mineral Waters ; they can then be mixed at once with the water in the foun- tain, and charged. These Solutions are so designed that they represent one gallon of the Mineral Water in 4 ounces of the Solution. Hence, to make any Mineral Water for each gallon required, take of the Solution 4 ounces. Water 1 gallon. Mix in a fountain, and charge with Carbonic Acid Gas to 60 or 80 pounds. All of the Solutions do not make up clear, and some of them do not remain clear after they are made ; but it is only necessary to shake them before using, as the Carbonic Acid, when charged, dissolves all the sediment. Keep the Solutions in dark-colored, half-gallon bottles or demijohns, in a cool, dark place. Do not forget to shake them thoroughly just before using. 3391. Apollinaris Water Solution. Bicarbonate of Sodium 3 ounces. Fine Dairy Salt 3 ounces. Glauber's Salt (Sulphate of Sodium) 1 ounce. Carbonate of Magnesium, 1 ounce. Water, enough to make 4 pints. Mix them, rubbing the Magnesium salt first through a sieve. Use 4 ounces of the mixture for each gallon of the Water desired, and charge as directed. 3392. Carlsbad Water Solution. Sulphate of Sodium (Soda), 160 grains. Carbonate of Sodium (Sal Soda) 40 grains. Sulphate of Magnesium (Epsom Salts) 20 grains. Fine Dairy Salt 20 grains. Chloride of Calcium 20 grains. Tartrate of Iron and Potassium, 2 grains. Water, enough to make 4 pints. 3393. Congress Water Solution. Fine Dairy Salt 1 pound. Caustic Soda 46 grains. Bicarbonate of Potassium 40 grains. Calcined Magnesium, 2 ounces. Water, enough to make 4 pints. SODA WATER SYRUPS 3394. Friedrichshall Water Solution. Bicarbonate of Sodium 1 % ounce. Sulphate of Soda (Glauber's Salt) 2 ounces. Sulphate of Potassium, J<< ounce. Fine Dairy Salt, 1 pound. Sulphate of Magnesium (Epsom Salts) 2 pounds. Chloride of Calcium 1 ]/ 2 ounce. Water, sufficient to make 4 pints. Mix them. Use 4 ounces of the mixture for each gallon of W 7 ater desired. Only a small portion of the salts are dissolved ; it must be well shaken. 3395. Hunyadi Janos Water. Epsom Salts 28 ounces. Glauber's Salt, 23 ounces. Fine Dairy Salt, 2 ounces. Sulphate of Potassium, 1 drachm. Bicarbonate of Sodium, y 2 ounce. Sulphite of Lime, , \]/ 2 ounce. Water, to make 10 gallons. This Water is so strong of the Salts that it is not expedient to make a solution, as in the other W T aters. 3396. Kissengen Water Solution. Bicarbonate of Sodium, 2 drachms. Fine Dairy Salt, 1 pound. Muriate of Ammonia 8 grains. Sulphate of Sodium 320 grains. Epsom Salts 4 ounces. Phosphate of Sodium, 26 grains. Carbonate of Magnesium, 1 ounce. Water, enough to make 4 pints. Rub the Carbonate of Magnesium through a sieve before adding it to the Solution. 3397. Magnesian Aperient or Citrate of Magnesium Solution. Citric Acid 8 ounces. Carbonate of Magnesium 8 ounces. Essence Lemon (945) 4 ounces. Dissolve the Citric Acid in 2 pints of hot Water, and add the Carbonate of Magnesium, previously rubbed through a sieve. This does not all dissolve. 870 SODA WATER SYRUPS. When effervescence has ceased, add the Essence Lemon, and make up the measure with Water to 4 pints. Use 1 pint of this Solution to each gallon of Water before charging. This makes an agreeable effective Citrate of Magnesia. 3398. Pullna Water Solution. Sulphate of Sodium \% ounces. Sulphate of Magnesium (Epsom Salts) 2^ ounces. Carbonate of Sodium 40 grains. Chloride of Calcium, 1 drachm. Chloride of Magnesium 1 drachm. Fine Dairy Salt, 1 drachm. Water, enough to make 4 pints. 3399. Pyrmont Water Solution. Sulphate of Sodium 40 grains. Epsom Salts, . 40 grains. Chloride of Magnesium, 26 grains. Chloride of Calcium, 100 grains. Carbonate of Sodium 180 grains. Sulphate of Iron 10 grains. Water, enough to make 4 pints. 3400. Seltzer Water Solution. Chloride of Calcium, 1 ounce. Chloride of Magnesium, 3 ounces. Fine Dairy Salt 1 ounce. Carbonate of Sodium 4 ounces. Phosphate of Sodium 140 grains. Pyrophosphate of Iron 30 grains. Sulphate of Sodium, 1 % ounces. Water, enough to make 4 pints. Dissolve the Iron in a portion of the Water, mix the other Salts with the rest of the Water, and mix the solutions. 3401. Spa Water Solution. Carbonate of Sodium 20 grains. Chloride of Calcium 10 grains. Epsom Salts, 20 grains. Sulphate of Iron 6 grains. Water, enough to make .... 4 pints. SODA WATER SYRUPS. TABELL.E — TABLETS. 871 3402. Vichy Water Solution. Sulphate of Potassium 360 grains. Sulphate of Sodium 160 grains. Phosphate of Sodium 50 grains. Fine Dairy Salt, 1 x / 2 ounces. Bicarbonate of Sodium ioj4 ounces. Carbonate of Ammonia 20 grains. Water, enough to make 4 pints. 3403. Zoedone. This is a proprietary drink, containing Iron and Mineral Phosphates in solution. An imitation may be made as follows : Solution Phosphate of Calcium 10 flounces. Phosphate of Iron (1880 scale salt), 1 ounce. Phosphate of Potassium, %. ounce. Phosphate of Sodium 40 grains. Orange Flower Water, 1 pint. Orange Essence, Soluble (948) 3 rl. ounces. Syrup \% gallon. Water, sufficient to make 10 gallons. Mix, and charge in a fountain or bottle. Directions for other drinks which are charged in fountains will be found under the Extracts from which they are prepared. See pages 421 to 428. TABELL^ — TABLETS. This title is applied rather indefinitely to a variety of prep- arations, either cut, moulded, or pressed into desired shape and size. Many preparations thus made are also called Troches or Lozenges, which see. The only official Tablets are Tabellaj Nitroglycerin! of the Br. P. 3404. Tabellae Nitroglycerini. Tablets of Nitroglycerini. Tablets of Chocolate, each weighing 2^ grains and containing ,,',„ grain <>f purr Nitroglycerine. The dose is 1 or 2 tablets. 872 TABELL/E — TABLETS. 3405. Compressed Tablets. These are made by compressing the dry medicinal substances, either alone or mixed with powdered Sugar, into round, flattened, convex Tablets or Loz- enges. This may be done by a small, hand tablet or pill compressor. Power machines are also made for this purpose, but as they are very expensive they are used only by large manufacturers. The Tablets as thus prepared are called by various names. Those corre- sponding to the formulas of well-known pills are called Compressed Pills or Powders. The small Tablets of Sodium, Ammonium, and Potassium salts, and some others, which are made without addition of sugar, are called Com- pressed Tablets. Those containing a small but definite quantity of active medicine, intended to be dissolved for hypodermic use, are called Hypoder- mic Tablets. The larger ones, in which the medicinal agent is mixed with sugar or other dilutent, are called Compressed Lozenges or Troches. And still another class of very small Tablets, which are made by triturating active medicinal agents with some dilutent (as powdered sugar), and which are intended to insure accuracy of dose, are called Compressed Triturates. As all of these are usually made by manufacturers who have machinery adapted for the business, it is unnecessary to give formulas for them. They are furnished in great variety by John Weyth & Brother, Philadelphia, who were the first to introduce compressed pills, etc., to the trade. Ordinary Lozenges are made by mixing confectioners' Sugar with more or less powdered Tragacanth or other adhesive gum, adding medicinal or flavor- ing ingredients as desired, and making into a mass with water. The mass is then rolled out and the Lozenges cut in various shapes as desired, and dried in a current of warm air. 3406. Fruit Tablets or Lozenges. These are supplied by the confectioners in great variety and of various shapes and sizes, being generally moulded convex, oval, or nearly round, or cut in squares. To make first-class Fruit Tablets, the Fruit Juices must be added to melted Rock Candy and the mixture boiled until it is of proper temper. It is then run into or through properly-constructed moulds, such as are used by confectioners, or run into pans and cut into square Tablets. When made with ordinary sugar, Tablets soon become soft and discolored. It is therefore necessary to use Rock Candy as the basis of the Tablets, Fruit Juice being added sufficient to flavor and color them. Flavoring Extracts are also added just before running in the moulds. Many other Tablets besides those made with Fruit Juices are made in the same manner, Cough Tablets particularly having a large sale. These usually contain some opiate in small quantities, strongly flavored with Oil of Anise or Paregoric, and col- ored black, brown, or red with Elderberry Juice, Caramel, or Cochineal coloring. For other Tablets, Troches, or Lozenges, see Troches. TANNIN OR TANNIC ACID. 873 3407. TANNIN OR TANNIC ACID. Acidum Tannicum. Ci4 H lo0 9 - This may be prepared from Nutgalls, in fine powder, by first exposing it to a moist atmosphere for 24 hours, then mixing it with sufficient washed Ether to form a soft paste. This is set aside, closely covered, for 6 hours, then enclosed in a strong canvas bag and quickly expressed with power between tinned iron plates, in order to obtain the liquid portion, which is reserved. The cake is then broken up and again treated in the same manner. The liquids are then mixed and allowed to evaporate spontaneously to a syrupy consistence, then spread upon glass plates and quickly dried. This process is too expensive to be employed commercially. Tannic Acid is an abundant constituent of plants, being found in nearly all barks, leaves, and roots, usually associated with glucosides. Tannin that is employed medicinally is obtained from Nut- galls, but for industrial purposes the Solutions of Tannin obtained from Hemlock, Oak, and other barks are extensively used for tanning, converting the gelatin of hides into insoluble tannate of gelatin. This combination is made advantageous in making many elixirs and other medicinal preparations from substances containing Tannin, as by the addition of Gelatin or Albumen it is removed, leaving them free to combine with Iron or other salts, which would otherwise be precipitated or discolored if not removed. Chemically, Tannin is now considered an Anhydride of Gallic Acid. In medicine, Tannin is used as an astringent, both internally and externally. The dose is 3 to 10 grains. 3408. Gallic Acid — Acidum Gallicum — HC 7 H 5 O fl .H 2 0. — This is pre- pared from Nutgalls by mixing the powder with Water to form a thin paste and exposing the mixture in a shallow dish for one month to a warm atmos- phere, stirring occasionally, with addition of Water. The mass is then expressed and the liquid rejected, the cake being then boiled with Water and tin- solution altered through animal charcoal. The liquid is then concentrated and set aside for crystals to form. Gallic Acid is used in medicine as an astringent, in doses of 5 to 15 grains. 3409. Pyrogallic Acid — Acidum Pyrogallicum — C 6 H fi () a . — This is prepared by subliming ( )allic Acid. It is used in making hair dye and in some photographic operations. 874 TELLURIUM. THALLIUM. THERIACA. TELLURIUM. Symbol, Te ; Atomic weight, 128. This is an elementary substance, classed with the non- metals. It is found only in small quantities associated with bismuth, gold, silver, and lead, chiefly in the gold mines of Transylvania. It is a grayish-white substance resembling bis- muth, and having, when decomposed, like arsenic, the odor of garlic. With Oxygen it forms two Oxides, Te0 2 Tellurium Dioxide and TeO s Tellurium Trioxide, which, uniting with the ele- ments of Water, form Tcllurous Acid, H 2 Te0 3 , and Telluric Acid, H 2 Te0 4 . It also forms, with Hydrogen, a gaseous compound, Telluretted Hydrogen, H 2 Te, similar in character- istics to Sulphuretted Hydrogen. The Acids of Tellurium form salts with bases, but they have no practical use in pharmacy or medicine. THALLIUM. Symbol, Tl ; Atomic weight, 203.7; Sp. gr., n.8. This is an elementary metal, discovered by Crooks, in 1861, similar in characteristics to mercury, silver, and lead. It is found in iron and copper pyrites and native sulphur. It is not employed in pharmacy or medicine. 3410. THERIACA. Br. Treacle. The uncrystallized residue of the refining of Sugar, or what is known in this country as " Golden Syrup," is official in the Br. P. under the above title. In ancient pharmacy a variety of confections or electuaries were known by this name and employed as antidotes to infections or poisons. They were TINCTORA — DYES. 875 composed of a great number of ingredients, the Theriaca AndromacJii of the Ph. L., 1746, containing over 60 substan- ces, with 1 grain of Opium in 75. The Electnaire Thc'riaque or Theriaca of the Paris codex contains 72 ingredients, with 1 grain of Opium in 72 grains. Confectio Damocratus, Mithri- date, Philonium Romanum, the Opiate of Soloman (see, also, 464), and some others are compounds of a great number of aromatics, similar to the Therique of the Paris codex, but are now unused, ordinary molasses, syrup, or honey being used when Theriaca or Treacle is directed. TINCTORA — DYES. Since the introduction of Aniline Dyes, put up in packages for coloring, the sale of other dyes, which was once quite a feature of the drug business, has much decreased, but there is still considerable demand for coloring substances aside from the package Dyes. The principal substances used for this purpose are therefore mentioned and a few recipes for coloring given. 3411. Alizarin — C 10 H O 3 .2H 3 O. — This preparation, which is also called Lazaric Acid or Madder Red, was formerly obtained from Madder by exhausting it with boiling Water, precipitating with Sulphuric Acid, wash- ing the precipitate and, while moist, boiling it with a concentrated Solution of Hydrate of Aluminium in Hydrochloric Acid, then mixing the solution with Hydrochloric Acid, when red flakes of impure Alizarin are deposited. This is then purified, recrystallized, etc. It is now artificially prepared from a coal tar product called Anthracen, by several complicated processes, and the cultivation of the Madder plant, Rubia Tinctorum, which was once a very important industry, has very much decreased. The Madder colors, of which Alizarin is the most important, are exten- sively used for dyeing calicoes, which are familiarly known as Madder prints. Turkey Red is one of the most brilliant colors produced with this substance, but by combining it with other colors a great variety of colors are produced. 3412. Annato — . Xrnatto or Oreflana.— This is a coloring matter obtained from outer pellicle of the seeds of Bt'xa ( irellana, by macerating the crushed seeds or seed pods in Water for several weeks and collecting the pulpy mass. purifying and concentrating to a stiff extract by evaporation. This is used 876 TINCTORA — DYES. for coloring orange or yellow, nankeen being a familiar color produced by it. It is also extensively employed for coloring butter, cheese, etc. Annattoine is the principal coloring matter of Annatto. 3413. Archil— Orchil. — This is a violet-red, purple, or blue coloring matter obtained from several species of lichens, the finest being from Roc- cella Tinctoria. As found in the market it is a liquid paste, which is either blue or red or violet color, as it contains more or less alkali or acid. It is of the same nature and derived from a similar source as Cudbear and Litmus, all being prepared from lichens collected on rocks near the sea, which are ground into a pulp with Water, Ammoniacal liquors added, and, after standing for some time, the dissolved coloring matter expressed, filtered, precipitated with Tin Solution, purified, redissolved, etc. Cudbear is Archil paste, made by grinding the weeds and treating with Ammonia, dried and ground, and usually much adulterated with salt or other inert substance. Litmus is- blue Archil mixed with some inert substance, as chalk, or boiled with the pith of some plants which absorb the coloring matter. The former is in the form of a cake and the latter in the form of small flattened cubes, in which shape the absorbing substance is cut before saturating with the Archil solution. Solution of Litmus is used as a test for acids, etc. (See page 231.) Archil, Cudbear, and Litmus are used for coloring purple, violet, red, and blue. 3414. Carmine. — This is an important coloring matter, obtained from Cochineal, Coccus Cacti, by precipitating its decoction with various acid salts, or by other treatment, which is employed by experienced workmen. It is soluble in Ammonia and alkaline solutions. It is chiefly employed as a pig- ment in solution as Liqtiid Rouge, Carmine Lnk, etc., but Cochineal, from which it is derived, is extensively used for dyeing, yielding the finest scarlet red, which is durable and permanent. 3415. Carthamin — C 14 H 16 7 — Pure Rouge. — This is the red coloring matter obtained from Safflower, Carthamus Tinctorius, by treating it repeat- edly with a weak solution of Carbonate of Sodium and then precipitating the coloring matter with excess of Citric or Acetic Acid. The Safflower Car- mine precipitated is then collected, washed, and dried. Pink Saucers, which are a well-known article in the toilet trade, are made by covering the inside of white saucers with Carthamin. Rouge, which is sold as a toilet requisite, is Carthamin, either alone or pre- pared in the form of a paste or powder, with other substances. Safflower is also used for coloring orange. 3416. Indigo.— A blue dyestuff, extracted from different species of Indi- go/era, by immersing them in Water and allowing to ferment. The Chro- mogene contained in the plants is first dissolved, then by the action of the air becomes oxidized, precipitating an insoluble coloring matter, which is col- lected, pressed, and dried, and is known as Indigo. It contains a variety of TIXCTORA — DYES. 877 principles, the most important of which is Indigotin or Indigo-blue, which is present to the extent of 50 to 60 per cent. Indigo is extensively used in dye- ing blue and for blueing clothes. 3417. Indigo Sulphate or Soluble Indigo. — This is prepared by gradu- ally adding 1 part of best powdered Indigo to 5 parts of Nordhausen Sul- phuric Acid or 8 parts of Commercial Sulphuric Acid, keeping the mixture cooled by immersing in cold water until combined, then heating for 10 or 12 hours. After standing a few days it becomes a dark pasty mass, which is known by the above names; also called Chemic Blue, Indigo Compound, Extract of Indigo, Indigo Paste, etc. This is used for dyeing, for making some kinds of liquid blueing, etc. 3418. Lac Dye. — In the preparation of Shellac from stick-lac or seed-lac, it is boiled with Water, which dissolves the red coloring matter of the insect which produces it. This is precipitated by Alum and is called Lac Dye. It is used for coloring red and purple. 3419. Extracts Used for Dyeing.— Many Extracts of Woods and other substances are now used for dyeing where formerly the substances them- selves were employed. This arises from the greater convenience of employ- ing concentrated preparations, decreased cost of transportation, superior facilities for extracting, etc. Catechu, also called Cutch and Terra faponica, is a native Extract pre- pared from the dark or heart-wood of Acacia Catechu. For small retail trade the purified Catechu, put up in boxes, is now generally sold. Extract of Logwood &nd Extract of Fustic, put up in a like manner, are also much sold in a retail way for domestic coloring. Extracts of other woods or like coloring substances are not generally sold by druggists, but are extensively prepared and used by dyers, the process being to percolate the ground woods, etc., with boiling water to exhaust them of their soluble coloring, then evaporate them to the proper consistence. Many woods, flowers, barks, roots, and other natural, vegetable, and chem- ical substances are used for coloring, but it is unnecessary to mention them here. Recipes for Coloring. To give intelligent recipes for dyeing different kinds of fabrics in different ways would fill a volume, and it is impossible, in this limited sketch, to give even an outline of the recipes and processes used ; but for convenience of druggists, who are often called upon for information in this line, a few only of the simple recipes used for domestic dyeing or coloring are given. The quantities directed arc for 1 pound of goods. A larger quantity requires less in proportion. 3420. Black— For Woolen Goods. — Extract of Logwood 2 ounces, Blue Vitriol 1 ounce. Dissolve them separately in hot rain or soft Water about 1 gallon. Dip the goods first in the solution of Blue Vitriol and. after a few 878 TINCTORA — DYES. moments, take out, drain, and add the solution of Blue Vitriol to the solution of Logwood Extract, then add the goods and keep the dye at a scalding heat for twenty minutes, working the goods occasionally, then take out, drain, and set the color by dipping in a hot bath of 3 gallons of Water in which a tea- cupful of salt is dissolved. Let the goods remain in the bath until cold. For Silk Goods, dye in the same manner, but to set the color dip in boil- ing soap suds instead of the salt solution. For Cotton Goods, boil the goods with the dye, with constant stirring, and set the color the same as for woolen goods. This is the ordinary Logwood-Black dye. One pound of Logwood chips may be used instead of the extract. Other blacks may be used, but this is the best for domestic dyeing. 3421. Blue — For Woolen Goods. — Alum 2)4 ounces, Cream Tartar 1^ ounce. Dissolve in 1 gallon of Water and boil the goods for 1 hour in the solution, then dip them into a mixture of Indigo Sulphate (3415) and Water, using sufficient of the Indigo preparation to get the desired shade of blue. A larger quantity, say \ l / z ounce, making a dark blue ; less quantity a light blue. For Silk Goods, the same dye as for woolen may be used, but finer shades of color are produced with the Aniline dyes. For Cotton Goods. Prussian Blue, in powder, 1 ounce, Oxalic Acid ]/ 2 ounce. Dissolve them in just sufficient Water to cover the goods, and dip the goods in the dye, working it well in by hand until well colored, then wring out and dip in Alum Water to set the color. This dye is also made by dissolving Prussiate of Potassium 1 ounce, Cop- peras (Sulphate of Iron) 1 ounce, each separately, in boiling Water, mixing the solutions, adding l / 2 ounce Sulphuric Acid, dipping the goods in the dye and setting the color with Alum Water. 3422. Brown — For Cotton, Wool, or Silk. — Catechu 4 ounces, Bichro- mate of Potassium 1 ounce, each dissolved separately in sufficient Water to dip the goods. Boil the goods first in the solution of Catechu, then dip in the solution of the Potash salt. A great variety of Browns may be made with Catechu by adding Copperas, Blue Vitriol, Acetate of Lead, etc. This dye is used for dyeing carpet work and for dark browns on wool and silk. For fine browns for silk Aniline dyes are generally used. 3423. Green — For Woolen Goods, first color yellow with y/ z ounces Alum and 1 pound of Fustic Wood, or 2 ounces Extract of Fustic, steeped in hot Water enough to cover the goods. When a good yellow is obtained by this dye, strain the liquid from the chips (if Fustic chips are used) and add Indigo Compound to the liquid sufficient to make the desired color, rub the goods well with the dye and rinse in Alum Water. For Silk Goods, color in the same way and set the color with hot soap- suds. For Cotton Goods, first color blue as directed (3421), then dip in the yellow (3430) until a fine green is obtained. TIXCTORA — DYES. 879 3424. Maroon. — Cudbear 2 ounces, steeped in Water sufficient to cover the goods, Alum 4 ounces, dissolved in 1 gallon hot Water. Dip the goods in the Alum Water, then in the Cudbear Solution. If a deep color is desired dip in a solution of 1 ounce Bichromate of Potash in half a gallon of hot Water. This colors nicely on woolen goods but not very well on cotton. For silk the finer Aniline dyes are generally used. 3425. Orange — For Woolen Goods. — Quercitron Bark 4 ounces, Lac Dye \Yz ounce. Soak them in hot Water and add Madder Compound \y 2 ounce, boil for 10 minutes, then put in the goods and boil for half an hour. By combining yellows and reds a variety of orange shades, ranging from yellow to reddish may be made. For Cotton Goods. — Dissolve Sugar of Lead, 2 ounces, in sufficient hot soft Water to well cover the goods ; dissolve Bichromate of Potash, 1 ounce, in Water enough to cover, then dip the goods first in the Lead Water, then in the solution of Bichromate of Potash. This makes a yellow color, which is changed to orange by dipping the goods carefully in a clear, weak solution of Lime (Lime Water), then rinsing in clear Water. 3426. Salmon or Nankeen — For Cotton or Woolen Goods. — Annatto 1 ounce, dissolve in sufficient hot Water to cover the goods, add sufficient Soft Soap to make a suds and boil the solution for 10 minutes, then add the goods and keep at a scalding heat for half an hour, then remove and rinse in cold soft Water. 3427. Red, Madder — For Woolen Goods. — Madder, best quality, % pound, soak over night in a copper or brass kettle, then add 1 ounce Madder Compound. After standing a little while add the goods and bring slowly to a scalding heat. Leave in the dye until the desired shade of color is pro- duced, then rinse in clear Water. It is necessary for the goods to remain some time in the dye to obtain a fine color. This makes a deep-red color but bright. Cochineal Scarlet, for silk or woolen. Cochineal, in fine powder, 1 ounce, Cream of Tartar 1 ounce, Madder Compound 2 ounces, Water sufficient to cover the goods. Put the Cream Tartar in the Water, boil for a few moments, add the Cochineal and then the Madder Compound, boil for 5 minutes, then add the goods and boil together for about an hour or until a bright scarlet color is obtained, then rinse thoroughly in clear Water. This is the brightest and most durable red. The Aniline reds are very fine but discharge their color when washed. Fine reds cannot be made on cotton except by experienced dyers. Turkey Red is made from Madder but requires peculiar manipulation. A fair red for cotton may be made by steeping Camwood in Water and adding Muriate of Tin. Pink may be made by diluting the Cochineal Dye with Water to obtain ired shade. Eosin, an Aniline dye, makes a fine pink. Strong solution of Kosin is used for red ink. making the most brilliant red ink known. 880 TINCTORA — DYES. TINCTURE — TINCTURES. 3428. Purple. — A common purple may be made by first dyeing blue as directed (3419), then dipping in Cudbear or Madder Red Dye, but finer shades are made with Aniline dyes. 3429. Violet. — On silk and woolen goods, good violet colors may be made by first coloring with red and then with blue. A Logwood violet is also made by adding acid freely to Logwood Lye. Fine violets are obtained from Aniline dyes. 3430. Yellow — For Woolen Goods. — Alum 2 ounces. Madder Compound 1 ounce. Fustic 8 ounces or Extract of Fustic 1 ounce. Dissolve the Alum in a small quantity of hot Water and add the Madder Compound, boil the Fustic 1 hour in a sufficient quantity of Water, strain the liquor from the chips and add the solution of Alum, etc. Boil together a few minutes and then put in the goods and boil for one hour, then rinse. For Cotton Goods. — Sugar of Lead 2 ounces, Bichromate of Potash 1 ounce. Dissolve the Sugar of Lead in sufficient hot rain Water as will cover the goods, and the Bichromate in sufficient cold Water. Dip the goods first in the Lead Water, then in the solution of Bichromate until the color is satisfactory. The foregoing include most of the colors which are generally used for domestic dyeing, except the Aniline package dyes, which are now exten- sively used for small work, and of which there is a great variety. TINCTURE — TINCTURES. Tinctures are solutions of medicinal substances in an Alco- holic or Hydro-alcoholic menstruum, differing from spirits chiefly in being prepared from non-volatile substances. They are the most used of any class of official preparations, and it is highly important that they should be well made, of the best material, and up to the highest standard of strength. The directions for making Tinctures in the U. S. 1880 Phar- macopoeia are much more definite than in former revisions. Many Tinctures that were formerly prepared by percolation are now, very sensibly, prepared by maceration, and in most of the present formulae, where percolation is employed, it is directed to moisten the drug and macerate it for 24 hours before packing in the percolator. This is a very important direction, for, in following the former authority, it was often the case that inexperienced druggists would pack the drugs in the percolator and begin percolating at once, having a tincture finished in a few hours, which would, of course, only partly TINCTUR/E — TINCTURES. 88 1 represent the medicinal value of the drug. By moistening the drug and allowing it to stand before packing, it has an oppor- tunity to "swell " and gives time for the medicinal properties to be dissolved or loosened, and it is therefore in a fit condi- tion for the process of percolation. Of all processes, however, which have been proposed for making Tinctures, none will be found so valuable and econom- ical as the process of water-bath percolation, which, by the influence of heat, dissolves and removes with the percolate, all the medicinal value of the drug. The formulae that are given for making Tinctures by water-bath percolation mostly conform to the standard of strength of the 1880 Pharmacopoeia. The change in the U. S. 1880 Pharmacopoeia to parts by weight, instead of definite weight and fluid measure, as for- merly, causes much inconvenience to American druggists who are not accustomed to preparing them in this manner. This is especially the case with Tinctures, owing to their varying specific gravity and the varying amount of extractive matter which even the same drug will yield by different methods of exhaustion. The Tinctures of American Pharmacy are now mostly made to represent 5, 10, 15, or 20 per cent, of the medicinal sub- stance, there being but few variations to this general rule. Those of British Pharmacy mostly represent 5, io, 12).., and 20 per cent., while those of German and French Pharmacy are all in decimal proportion. The official formulas which follow, therefore, are arranged for definite weight and measure as well as in parts. Tin for- mulas of the Br., German, and man)- of those of the French Pharmacopoeias art: given as well as the U.S., for in this coun- try tin-) are frequently called for. The following are' those official in the authorities mentioned: 3431. Tinctura Absinthii. G. P. Tincture >>/ 11 'ormwood. Wormwood i part. Diluted Alcohol 5 parts. Make a Tincture by maceration or percolation. 882 TINCTUR.E —TINCTURES. 3432. Tinctura Aconiti. Tincture of Aconite. The U. S. P., 1880, formula is: Aconite (Root), .... 400 parts or 1 1 ounces av. Tartaric Acid, 4 parts or 48 grains. Alcohol, sufficient to make 1000 parts or 2 pints. Moisten the powder with 6 fl. ounces of Alcohol in which the Tartaric Acid has previously been dissolved, and macerate for 24 hours; then pack it firmly in a cylindrical glass percolator and gradually pour Alcohol upon it until 2 pints of Tincture are obtained. This Tincture contains 40 per cent, of Aconite. MADE BY WATER-BATH PERCOLATION. Aconite Root, in No. 60 powder, . . 11 ounces av. Tartaric Acid, 48 grains. Alcohol, sufficient to make .... 2 pints. Moisten the Aconite with 6 ounces of Alcohol and pack.it very firmly in the water-bath percolator. Pour upon it a pint of Alcohol and set in a warm place for 4 days, then heat mod- erately and, after 1 hour, begin to percolate slowly, adding Alcohol to the drug and continuing the heat and percolation until 2 pints have passed. Dissolve the Tartaric Acid in the Tincture and filter. The Alcohol remaining in the drug after percolation may be recovered by distillation, and used in liniments, etc. The Br. P. formula is Aconite Root 2]/ 2 ounces av., Rectified Spirit 20 fl. ounces, made in the same manner, the finished Tincture representing 10 per cent, of the drug. The German official is made 1 part of the Root with 10 parts of diluted Alcohol. The French Alcoolatnre d'Aconit is made from the fresh Root and 90 per cent. Alcohol, equal parts, by maceration and expression. The U. S. Tincture of Aconite is given as an arterial seda- tive in doses of ^ to 5 minims. Three or four times as much of the Br. or German preparations may be given. TIXCTUR.E — TINCTURES. " 883 Tincture of Aconite Leaves is also kept in most drug stores, and fre- quently prescribed or called for. although not officinal ; much care must, therefore, be used to prevent mistakes that might occur from misunderstand- ing as to the two preparations. This was formerly official in the U. S. P.. made with i part Aconite Leaves and 8 parts diluted Alcohol. The dose was 5 to 1 5 grains. 3433. Fleming's Tincture of Aconite. — This is a stronger Tincture of Root prepared by macerating Aconite Root, in fine powder, 16 ounces aw, with 1 pint of Alcohol, for five days, then transferring to a percolator and adding Alcohol, percolating slowly until 24 flounces are obtained. This is double the strength of the official Tincture. 3434. Etherial Tincture of Aconite (Paris Codex) is made by macerat- ing or percolating 4 parts of Aconite Root with 16 parts (by weight) of Ether. It is used externally. 3435. Tinctura Aloes. Tincture of Aloes. Purified Aloes, ...... JO parts or 3^ ounces av. Extract of Liquorice, . . 10 parts or 3^ ounces av. Diluted Alcohol, sufficient to make 100 parts or 2 pints. Mix the powders with a pint and a half of diluted Alcohol, and macerate the mixture for seven days in a closed vessel; then filter through paper, adding through the filter enough diluted Alcohol to make the Tincture measure 2 pints. U. S. 1880. MADE BY WATER-BATH l'KKCOLATION. Purified Aloes, in moderately fine powder 3 ' 4 minces av. Extract of Liquorice, in moderately fine powder 3' 4 ounces av. Diluted Alcohol, sufficient to make . 2 pints. Mix the drugs and agitate them with 2.X fl.ounces of diluted Alcohol; Cul a piece of burlap or coarse cloth and place in the bottom, on tin- perforated diaphragm of the water-bath per- colator. Pour the mixture into the percolator and let it stand in a warm place for two days ; then heat moderately, and, after one hour, begin t<> percolate, adding diluted Alcohol through 884 TINCTUR/E — TINCTURES. the percolator to make 2 pints of the Tincture. A little sedi- ment will be found at the bottom after the Tincture has cooled, as the warm diluted Alcohol dissolves a little more of the drugs than it will retain in solution. Forty grains of Carbon- ate of Potassium then added to the Tincture will nearly dis- solve the precipitate and will greatly improve the preparation. The Br. P. formula is Socotrine Aloes y 2 ounce av., Extract of Liquorice \ l /> ounce av., Proof Spirit a sufficiency. Mac- erate for seven days in 15 fl. ounces of the Spirit, then filter and add sufficient Proof Spirit through the filter to make 20 fi. ounces. The G. P. formula is Aloes 1 part, Alcohol 5 parts, prepared in the same manner. The U. S. Tincture of Aloes is given as a purgative in doses of ^ to 1 fl. drachm or more. 3436. Tinctura Aloes Composita. G. P. Elixir ad Longam Vitam. Aloes 6 parts, Rhubarb, Gentian, Zedoary, Saffron, each 1 part, diluted Alcohol 200 parts. Make a Tincture by maceration. 3437. Tinctura Aloes et Myrrhae. Tincture of Aloes and Myrrh [Elixir Proprietatis). Purified Aloes, .... 10 parts or 2^ ounces av. Myrrh, 10 parts or 27/q ounces av. Alcohol, sufficient to make 100 parts or 2 pints. Mix the powders with i l /> pint of Alcohol and macerate the mixture for seven days in a closed vessel, then filter through paper, adding through the filter enough Alcohol to make the Tincture measure 2 pints. U. S. 1880. This may also be made by water-bath percolation in the same manner as is directed for making Tincture Aloes (3435)- It is given as a laxative and regulator and for worms, etc. The dose is 30 minims to a teaspoonful or more. TIXCTL'R-E — TINCTURES. 885 3438. Tinctura Amara. G. P. Bitter Tincture — Bittertropfen. This is prepared by maceration or percolation from Gentian, Centaury, each 3 parts, Orange Peel 2 parts, Orange Berries, Zedoary, each 1 part, diluted Alcohol 50 parts. It is an aro- matic bitter. 3439. Tinctura Arnicae Florum. Tincture of Arnica Flowers. Arnica Flowers, .... 20 parts or 6^ ounces av. Diluted Alcohol, sufficient to make 100 parts or 2 pints. Moisten the Arnica Flowers with 12 fl. ounces of diluted Alcohol and macerate for 24 hours, then pack it firmly in a cylindrical percolator and gradually pour diluted Alcohol upon it until 2 pints of Tincture are obtained. U. S. 1880. MADE BY WATER-BATH PERCOLATION. Arnica Flowers, in coarse powder, . . 6 ounces av. Alcohol, 22 fl. ounces. Water, sufficient to make 2 pints. Moisten the Arnica with 8 ounces of Alcohol and pack' very firmly in the water-bath percolator, pour upon it the remaining 14 ounces of Alcohol and set in a warm place for one daw then heat moderately and, after one hour, begin to percolate, adding Water to the drug in the percolator after the Alcohol has disappeared and continuing the heat and percolation with Water until 2 pints of the Tincture arc obtained. Let it stand for a ivw days and filter. The Arnica Flowers can besl be reduced to a coarse powder by rubbing them through a coarse sieve. It will be noticed that the proportion of Alcohol is greater than the [880 Phar- macopoeia directs, but it lias been found necessary to use a larger quantity in order to retain the properties in solution, as 886 TINCTUR/E — TINCTURES. by water-bath percolation a much stronger Tincture is made than by the ordinary method. The German formula directs I part of the Flowers to 10 parts of diluted Alcohol. Tincture of Arnica is chiefly used externally. 3440. Tinctura Arnicae Radicis. Tincture of Arnica Root. Arnica Root, in No. 40 powder, 10 parts or 3^ ounces av. Diluted Alcohol, sufficient to make 100 parts or 2 pints. Moisten the powder with 3 ounces of diluted Alcohol and macerate for 24 hours, then pack it firmly in a cylindrical per- colator and gradually pour diluted Alcohol upon it until 2 pints of the Tincture are obtained. U. S. 1880. The Br. formula is essentially the same. When this Tincture is desired by physicians it should be so stated in the prescription. If " Tincture Arnica " only is writ- ten the Tincture of Arnica Flowers should be dispensed. MADE BY WATER-BATH PERCOLATION. Arnica Root, in No. 40 powder, ... 3 ounces av. Diluted Alcohol, sufficient to make . 2 pints. Moisten the drug with 3 ounces of diluted Alcohol and pack firmly in the water-bath percolator, pour upon it 24 ounces of diluted Alcohol and set in a warm place for. 24 hours, then heat moderately and, after one hour, begin to percolate, adding diluted Alcohol to the drug and continuing the heat and per- colation until 2 pints of the Tincture are obtained. 3441. Tinctura Aromatica. G. P. Aromatic Tincture. This is prepared by maceration or percolation from Cinna- mon 5 parts, Ginger 2 parts, Galangal Root, Cloves, Cardamom, each 1 part, and diluted Alcohol 50 parts. It is used as an aromatic addition to other preparations. TINCTURiE — TINCTURES. 887 3442. Tinctura Asafoetidae. Tincture of Asa fetid a. Asafetida, bruised, ... 20 parts or 5^ ounces av. Alcohol, sufficient to make 100 parts or 2 pints. Mix the Asafetida with a pint and a half of Alcohol and macerate for seven days in a closed vessel, then filter through paper, adding enough Alcohol through the filter to make the Tincture measure 2 pints. U. S. 1880. This Tincture may be made by water-bath percolation in the same manner as Tincture of Aloes, but, as it is so difficult to clean a vessel in which it is made, it may not be advisable to use a water-bath percolator for this purpose. It is most con- venient to keep a wide-mouth jar expressly for making Tinc- ture of Asafetida. allowing it to macerate for an indefinite time and filtering off a pint, more or less, as is required to fill the shelf bottle. The German preparation is the same as the U. S. The Br. P. directs 2^ ounces av. of the Gum-Resin to make 20 fl. ounces with Rectified Spirit. The dose is ^ to I fl. drachm as an anti-spasmodic. 3443. Tinctura Aurantii Amari. Tincture of Bitter Orange Pec/. Bitter Orange Peel, ... 20 parts, or 6 1 /^ ounces av. Diluted Alcohol, sufficient to make IOO parts or 2 pints. Moisten tin powder with 6 ounces of Diluted Alcohol and macerate for 24 hours; then pack it moderately in a conical percolator and gradually pour Diluted Alcohol upon it until 2 pints of the Tincture are obtained. MADE BY W \ iKk-i: A III PERC0LA1 I' >N. Mitt'T ' )r.iii;.;e Peel, in No. 30 powder, . (> ounces av. Diluted Alcohol, sufficient to make . 2 pints. Moisten the drug with 6 ounces of Diluted Alcohol and macerate in a closed vessel for 2 ) hours, then pack' moderately 888 TINCTUR.E — TINCTURES. in the water-bath percolator, pour upon it a pint and a half of Diluted Alcohol and set in a warm place for 24 hours. Then heat very moderately and after one hour begin to percolate, adding Diluted Alcohol to the drug and continuing the heat and percolation until 2 pints of the Tincture have passed. Set this aside for a few days to allow the albuminous matter to separate, and then filter. The Br. and German formulas are the same as the U. S. This is given as an aromatic bitter in doses of a teaspoonful or more. 3444. Tinctura Aurantii Dulcis. Tincture of Sweet Orange Peel. Sweet Orange Peel recently separated from the fresh fruit and deprived of the inner white layer, ... 20 parts or 6 ounces av. Alcohol, sufficient to make . 100 parts or 2 pints. Mix the Orange Peel previously cut into small pieces with 80 parts or \ l / 2 pints of Alcohol, and macerate for 24 hours, then pack it moderately in a conical percolator, and gradually pour Alcohol upon it until 100 parts or 2 pints of Tincture are obtained. U. S. 1880. This is a new officinal tincture used chiefly for flavoring other preparations. The short time which is given for maceration seems insufficient, and certainly is unless the peel is cut very fine and bruised so as to rupture the oil cells as much as possi- ble. It will be much better to add the Alcohol to the peel, chopped very fine, and allow it to remain upon it, instead of percolating as directed. After standing a few weeks it may be filtered off for use. The Br. P. Tinctura Aurantii Rcccntis is similar to this, but stronger. 3445. Orange Fruit Tincture. Oranges, medium size, sweet, No. 1 2, or 4 pounds av. Alcohol 4 pints. Water, sufficient. Peel the Oranges as you would an apple, taking off a peeling thick enough to contain all the oil cells, squeeze out the juice of the Oranges with a lemon TI.\CTl"R.-E — TINCTURE* squeezer, chop or cut the peel fine and put in a wide-mouth jar or other con- venient vessel, pour upon it the Alcohol and expressed juice of the Oranges, macerate for a week or more, add 2 pints of Water and macerate again for a week, then pour off the liquid, pack the macerated peel in a funnel or perco- lator, and percolate it, first with the poured off liquid, then add Water enough through the drugs to make the measure a gallon. If cloudy when filtered add a very little Alcohol. This is a finely-flavored preparation and may be used whenever Tincture of Sweet Orange is directed. It is far superior to any other Tincture of Orange. It should be made when oranges are cheap in sufficient quantity to last a year. 3446. Tinctura Belladonnae. Tincture of Belladonna. Belladonna Leaves, ... 15 parts or 4^ ounces av. Diluted Alcohol, sufficient to make 100 parts or 2 pints. Moisten the powder with 6 fl. ounces of Diluted Alcohol and macerate for 24 hours, then pack it firmly in a cylindrical per- colator and gradually pour diluted Alcohol upon it until 2 pints of Tincture are obtained. U. S. 1880. MADE BY WATER-BATH PERCOLATION. This may be made by water-bath percolation in the same manner as is directed for making Tincture Arnica Root. The Br. P. formula directs only I ounce of the drug with 20 of Proof Spirit, the product being only about one third as strong as the U. S. The U.S. Tincture is a narcotic poison, acting as a sedative in small doses. The dose is 3 to 10 minims. 3447. Tinctura Benzoini. Tinet nrc of Benzoin. Benzoin 20 parts or 6 ounces av. Alcohol, suflii ienl to make [00 parts or 2 pints. Mix the powder with a pint and a halt of Alcohol and mac- erate for seven day. iii a closed vessel, then filter through paper, adding through the filter enough Alcohol t" make the Tincture measure 2 pints. {J. S. [880. Tin German Tincture Benzoes is the same. 890 TINCTURE — TINCTURES. This may be made by water-bath percolation in the same manner as is directed for making Tincture Aloes. This is used in making some other preparations and in mak- ing Aromatic Lotions, etc. 3448. Tinctura Benzoini Composita. Compound Tincture of Benzoin. Benzoin, 12 parts or 3^ ounces av. Purified Aloes, ... 2 parts or 236 grains. Storax y 8 parts or 2]/^ ounces av. Balsam of Tolu, ... 4 parts or lyi ounce av. Alcohol, sufficient to make 100 parts or 2 pints. Mix the gums, etc., with a pint and a half of Alcohol and macerate the mixture for seven days in a closed vessel, then filter through paper, adding enough Alcohol through the filter to make the Tincture measure 2 pints. U. S. 1880. This may be made by water-bath percolation in the same manner as directed for making Tincture of Aloes. The Br. P. formula is Benzoin 2 ounces av., Prepared Storax \ x /t ounce av., Balsam Tolu x / 2 ounce av., Socotrine Aloes 160 grains, Rectified Spirit to make 20 fl. ounces. This Tincture was once a popular panacea known as " Friar s Balsam. The dose is ^ to 1 fl. drachm on sugar or in sweetened water. 3449. Tinctura Bryoniae. Tincture of Bryonia. Bryonia, recently dried, in No. 40 powder, ... 10 parts or 2^ ounce av. Alcohol, sufficient to make 100 parts or 2 pints. Moisten the powder with 3 fl. ounces of Alcohol and macer- ate for 24 hoars, then pack it firmly in a cylindrical percolator and gradually pour Alcohol upon it until 2 pints of Tincture are obtained. U. S. 1X80. TIXCTUR.-E — TINCTURES. S91 This Tincture may also be made by water-bath percolation in the same manner as is directed for making Tincture Aconite Root. It is used as a hydrogogue cathartic in doses of I to 2 fi. drachms. 3450. Tinctura Buchu. Br. Tincture of Buchu. Buchu Leaves, in No. 20 powder, . 2^ ounces av. Proof Spirit, 20 fl. ounces. Macerate the Buchu for 48 hours in 15 fl. ounces of the Spirit in a closed vessel, agitating occasionally, then transfer to a percolator and, when the fluid ceases to pass, continue the per- colation with the remaining 5 fl. ounces of Spirit, press the drugs remaining in the percolator, filter the liquids obtained and add through the filter sufficient Proof Spirit to make a pint. This is given in doses of I to 4 teaspoonfuls as a diuretic, etc. 3451. Tincture Calami. G. P. Tincture of Calamus {Sweet Flag). Calamus 1 part, diluted Alcohol 5 parts. Prepare a Tinc- ture by maceration or percolation. This is used as a stomachic and for flavoring other ■ preparations. 3452. Tinctura Calendulae. Tincture of Calendula or Marigold. Calendula, in No. 20 powder, .... 6 ounces av. Diluted Alcohol, sufficient to make . 2 pints. Moisten the powder with [2 fl.ounces of diluted Alcohol and macerate for 24 hours, then pack- it firmly in a cylindrical percolator, and gradually pour diluted Alcohol upon it until 2 pints of Tincture are obtained. U. S. [880. 892 TIXCTURiE — TINCTURES. The U. S. official Tincture of Calendula is intended to be made from the herb, but it is much more frequently made from the flowers, which are preferable for the purpose. .MADE BY WATER-BATH PERCOLATION. Calendula (flowers), in No. 20 powder, 6 ounces av. Alcohol, 22 fl. ounces. Water, sufficient to make 2 pints. Make in the same manner as is directed for making Tincture of Arnica Flowers. The Calendula Flowers, when dry, can be reduced to a coarse powder by rubbing through a coarse sieve. The proportion of Alcohol used in this formula is greater than the pharmacopoeia directs, but is no more than is required to hold the medicinal properties in solution. 3453. Tinctura Calumbae. Tincture of Calnmba. Calumba, No. 20 powder, . 10 parts or 3 ounces av. Alcohol, ) each sufficient to Water, \ make . . . 100 parts or 2 pints. Mix Alcohol and Water (by weight) in proportion of 3 parts of Alcohol to 2 parts of Water, and, having moistened the powder with 3 ounces of the mixture, macerate for 24 hours, then pack it in a cylindrical percolator and gradually pour men- struum upon it until 2 parts of Tincture are obtained. MADE BY WATER-BATH PERCOLATION. Calumba, in No. 20 powder, .... 3 ounces av. Alcohol, ) , rr ■ 1 f each sufficient to make . . 2 pints. Water, ) r Mix Alcohol and Water as above and make a Tincture by water-bath percolation as directed for making Tincture Arnica Root. The Br. P. directs 2^4 ounces of Calumba to be made into 20 fl. ounces of Tincture with Proof Spirit. This is given as a bitter tonic and stomachic in doses of *4 to 1 teaspoonful. TINCTURiE — TINCTURES. 893 3454. Tinctura Camphorae Composita. Br. Compound Tincture of CampJwr — ■ Paregoric. The Br. P. gives the following formula under the above title, the preparation corresponding nearly to the U. S. P. Tinctura Opii Camphorata and the G. P. Tincture Opii Bcnzoica (which see) : Opium, in powder 40 grains. Benzoic Acid 40 grains. Camphor, 30 grains. Oil of Anise, y 2 fl. drachm. Proof Spirit 20 fl. ounces. Macerate for seven days in a closed vessel, with occasional agitation, then filter and add sufficient Proof Spirit to make 20 fl. ounces. A fl. drachm contains % grain Opium. The dose is 15 to 60 minims. 3455. Tinctura Cannabis Indicae. Tincture of Indian Cannabis — Tincture of Indian Hemp. Indian Cannabis, 23/ ounces av. Alcohol, sufficient to make .... a pint. Moisten the powder with 3 fl. ounces of Alcohol and macer- ate for 24 hours, then pack it firmly in a cylindrical percolator and gradually pour Alcohol upon it until a pint of Tincture is obtained. U. S. l88o. MADE BY WATER-BATH PERCOLA I [I IN. Indian Cannabis, in No. 40 powder, . ^]/, ounces av. Alcohol, sufficient to make .... 2 pints. Moi^tc-n the powder with .\ ounces of Alcohol, pack firmly in the water-bath percolator, pour upon it a pint and .1 half of Alcohol and sel in a warm place for two days, then heat mod- erately and, after one hour, begin to percolate, adding Alcohol to tin- drug and continuing the heat and percolation until 2 • if t he Tincture have passed. 894 TINCTUR/E — TINCTURES. The Br. P. directs I ounce av. of Extract of Indian Hemp to be dissolved in Rectified Spirit 20 fl. ounces. The German formula directs 1 part of Extract of Indian Hemp to be dissolved in 19 parts (by weight) of Alcohol. The dose of the U. S. Tincture is 20 to 40 minims, of the Br. and German preparations 5 to 20 minims. 3456. Tinctura Cantharidis. Tincture of CantJiaridcs. Cantharides, 5 parts or 606 grains. Alcohol, sufficient to make . 100 parts or 2 pints. Moisten the powder with an ounce of Alcohol and pack it firmly in the cylindrical percolator, then gradually pour Alco- hol upon it until 2 pints of Tincture are obtained. MADE BY WATER-BATH PERCOLATION. Cantharides, in No. 60 powder, . . . 600 grains. Alcohol, sufficient to make 2 pints. Make in the same manner as directed for Tincture Cannabis Indica. The dose is 3 to 15 drops. The Br. P. formula is Cantharides, in coarse powder, y± ounce av., Proof Spirit 20 fl. ounces, made by maceration. Dose, 5 to 20 minims. It is only about one third the strength of the U. S. preparation. The G. P. directs Cantharides 1 part, Alcohol 10 parts, being double the strength of the U. S. 3457. Tinctura Capsici. Tincture of Capsicum. Capsicum, 5 parts or 600 grains. Alcohol, ) each sufficient to Water, i make .... 100 parts or 2 pints. Mix Alcohol and Water in the proportion of 19 parts of Alcohol to 1 part of Water, and, having moistened the pow- der with y 2 fl. ounce of the mixture, pack it firmly in a cylin- drical percolator, then gradually pour menstruum upon it until 2 pints of Tincture are obtained. U. S. 1880. TINCTUR.E — TINCTURES. 895 MADE BY WATER-BATH PERCOLATION. Capsicum, in No. 30 powder, .... 600 grains. ' ,- each sufficient to make ... 2 pints. Water, * Mix Alcohol and Water in the proportion of 19 parts of Alcohol to 1 part of Water and moisten the drug with an ounce of the mixture, pack it firmly in the water-bath percola- tor, pour upon it a pint and a half of the menstruum and set in a warm place for two days, then heat very moderately and, after one hour, begin to percolate, adding the menstruum to the drug and continuing the heat and percolation until 2 pints of the Tincture have passed. The Br. P. formula directs ^ ounce of Capsicum with suf- ficient Rectified Spirit to make 20 fl. ounces. The G. P. directs 1 part of Capsicum with 10 parts of Alco- hol, to be made by maceration. It is double the strength of the U. S. or Br. preparation. Tincture of Capsicum is much used externally in liniments, and is given as a warm stimulant in doses of 5 to 30 minims. 3458. Tinctura Cardamomi. Tincture of Cardamom. Cardamom, 15 parts or 4^$ ounces av. Diluted Alcohol, sufficient to make 100 parts or 2 pints. Moisten the powder with 4 fl. ounces of diluted Alcohol and macerate for 24 hours, then pack in a Cylindrical percolator and gradually pour diluted Alcohol upon it until 2 pints of the Tincture are obtained. U. S. 18S0. \i \\A : . i:\ \\.\ 1 ER-BA ill PERCOL VTH IN. Cardamom, in No. 30 powder, . . . 4^ ounces av. Diluted Alcohol, sufficient to make . 2 pints. Make in the same manner as directed for Tincture Arnica Root (3440). This is given as an aromatic stimulant in doses ol % to 1 teaspoonful. 896 T I NCTU R.E — TINCTU RES. 3459. Tinctura Cardamomi Composita. Compound Tincture of Cardamom. Cardamom, 20 parts or 280 grains. Cinnamon 20 parts or 280 grains. Caraway, 10 parts or 140 grains. Cochineal, 5 parts or 70 grains. Glycerin, 60 parts or 1 x / 2 fl. ounce. Diluted Alcohol, sufficient to make IOOO parts or 2 pints. Mix the drugs and reduce them to a moderately coarse pow- der, moisten them with an ounce of diluted Alcohol, pack them firmly in a cylindrical percolator and gradually pour diluted Alcohol upon them until 30^2 fl. ounces have passed ; to this add the Glycerin and mix them thoroughly. Filter if necessary. U. S. 1880. This may be made by water-bath percolation in the same manner as Tincture of Arnica Root (3440). The Br. P. formula directs Cardamom Seeds }£ ounce, Cara- way Fruit (seeds) ^ ounce, Raisins, freed from seeds, 2 ounces. Cinnamon Bark }4 ounce, Cochineal 55 grains, Proof Spirit 20 fl. ounces, to make a Tincture. This is a pleasant aromatic, used chiefly for flavoring other preparations. Dose, a teaspoonful. It is quite a favorite addition to bitters or other stomachics, in which it is used chiefly as a flavoring. 3460. Tinctura Cascarillae. Br. Tincture Cascarilla. Cascarilla Bark, in No. 40 powder, . 2]/ 2 ounces av. Proof Spirit, 20 fl. ounces. Make a Tincture by macerating 48 hours in 15 fl. ounces of tlic Spirit, then percolating with the addition of enough Spirit through the percolator to make 20 fl. ounces. This is a tonic and is given in doses of ^ to 2 fl. drachms. ' TIXCTURJE — TIN'CTUKES. 3461. Tinctura Castorei. G. P. Tincture of Castor. Castor, 1 part. Alcohol, 10 parts. Make by maceration. The formula for this Tincture was official in the U. S. 1870 Pharmacopoeia, Castor, bruised, 2 troyounces, Alcohol 2 pints. Made by maceration. It is given as an antispasmodic. Dose, 20 to 60 minims. 3462. Tinctura Catechu Composita. Compound Tincture of Catechu — 18S0. Tincture of Catechu — U. S. 1870. Catechu, in No. 40 powder, 12 parts or 3^ ounces av. Cinnamon, in No. 40 powder, 8 parts or 2.y 2 ounces av. Diluted Alcohol, sufficient to make 100 parts or 2 pints. Mix the powders, and, having moistened the mixture with 5 fl. ounces of diluted Alcohol, macerate for 24 hours, then pack it firmly in a cylindrical percolator and gradually pour diluted Alcohol upon it until 2 pints of Tincture are obtained. U. S. 1880. The U. S. 1870 formula was Catechu 3 tr.ounces, Cinnamon 2 tr.ounces, Diluted Alcohol sufficient to make 2 pints. It was called, simply, Tincture of Catechu. The Br. formula is Catechu 2 l / 2 ounces av., Cinnamon Hark 1 ounce, Proof Spirit 20 fl. ounces. Making a preparation nearly the same as the l T . S. The German Tincture Catechu is prepared from Catechu 1 part, diluted Alcohol 5 parts, by maceration. This may be made by water-bath percolation as directed foi Tincture Aloes 1 $435). This Tincture is given as an aromatic astringent in doses of y 2 to mfuls. It is a favorite addition Co diarrhoea mixtures, astringenl washes for spongy gums, and othei similar preparal ions. 898 TINCTURE — TINCTURES. 3463. Tinctura Chinoidini. G. P. Tincture of Chinoidin. Chinoidin, 10 parts. Diluted Alcohol, 85 parts. Hydrochloric Acid, 5 parts. Dissolve the Chinoidin in the liquids and filter. Dose ]/>, to a teaspoonful or more; This is a tonic and antiperiodic used particularly for chills, fever and ague, and malaria. Its extreme bitterness can be overcome in a measure by adding 30 grains of Extract of Liquorice, in powder, to each fl. ounce. 3464. Tinctura Chiratae. Tincture of CJiirata. Chirata, in No. 40 powder, 3 ounces av. Diluted Alcohol, sufficient to make . 2 pints. Moisten the powder with 3 fl. ounces of Diluted Alcohol and macerate for 24 hours, then pack it firmly in a cylindrical per- colator and gradually pour diluted Alcohol upon it until 2 pints of Tincture are obtained. U. S. 1880. This may be made by water-bath percolation in the same manner as is directed for making Tincture Arnica Root (3440). The Br. P. formula is Chirata 2^ ounces, Proof Spirit to make 20 fl. ounces. It is a bitter stomachic, similar to Tincture of Gentian. The dose is y 2 to 1 teaspoonful. 3465. Tinctura Chloroformi Composita. Br. Tincture of Chloroform. Chloroform, 1 fl. ounce. Rectified Spirit, 4 fl. ounces. Compound Tincture of Cardamom, . . 5 fl. ounces. Mix them. Although this preparation is not official in the U. S., it is frequently prescribed and used in this country. It is nearly double the strength of the U. S. official Spirit of Chloroform. TINCTURES — TINCTURES. 3466. Tinctura Chloroformi et Morphinae. Br. Tincture of Cliloroform and Morphine — " Chlorodyne." Contains in 10-minim dose. Chloroform, . . . . 1 fl. ounce. \)/± minim. Ether, 2 fl. drachms. ^ minim. Rectified Spirit, . . 1 fl. ounce. \]± minim. Hydrochlorate of Mor- phine, 8 grains. ^ grain. Diluted Hydrocyanic Acid, y 2 fl. ounce. ^ minim. Oil of Peppermint, . 4 minims. S L- minim. Liquid Extract of Li- quorice, 1 fl. ounce. 1^ minim. Treacle, 1 fl. ounce. Syrup, a sufficiency to make 8 fl. ounces. Dissolve the Hydrochlorate of Morphine and Oil of Pepper- mint in the Spirit and add the Chloroform and Ether. Mix the Liquid Extract of Liquorice and Treacle with 3 fl. ounces of Syrup and add to the previously formed solution, mix them thoroughly, add the Hydrocyanic Acid and make up the vol- ume of the liquid with Syrup to 8 fl. ounces. This is a new Br. P. official intended to supply a popular demand for " Chlorodyne," which was formerly a proprietary medicine. Other formulas for Chlorodyne will be found else- where. It is given in 5 to 10 minims doses as an anodyne. 3467. Tinctura Cimicifugae. Tincture of Cimicifuga {Black Cohosh) — Tincture of Actcea. Black Cohosh, in No. 60 powder, . Alcohol, sufficient to make . . . $ l /2 ounces a v. 2 pints. Moisten the powder with 4 ounces of Alcohol and macerate for 24 hours, then pack it firmly in a cylindrical percolator and gradually pour Alcohol upon it until 2 pints of Tincture art- obtained. U. S. 1880. 900 TINCTUR.E — TINCTURES. MADE BY WATER-BATH PERCOLATION. Black Cohosh, in No. 50 powder, . 5^ ounces av. Alcohol, sufficient to make .... 2 pints. Moisten the powder with 3 ounces of Alcohol and pack firmly in the water-bath percolator, pour upon it a pint and a half of Alcohol and set in a warm place for two days, then heat moderately, and, after one hour, begin to per- colate, adding Alcohol to the drug and continuing the heat and percolation until 2 pints of the Tincture have passed. The Br. P. directs Cimicifuga 2y 2 ounces to be made with Proof Spirit into 20 fi. ounces of Tincture by maceration and percolation. This is given as a tonic and anti-rheumatic in doses of 15 to 60 minims. 3468. Tinctura Cinchonae. Tincture of Cinchona — Tinctura Chines. G. P. Yellow Cinchona, in No. 60 powder, . . 6 ounces av. Glycerin, 2 fi. ounces. co 10 , eac ^ su f£ c i ent to ma ke . . 2 pints. Water, I Mix the Glycerin with 23 fl. ounces of Alcohol and 7 fl. ounces of Water, and, having moistened the powder with 6 ouncesof the mixture, macerate for 24 hours, then pack it firmly in a cylindrical glass percolator and gradually pour on the remain- der of the mixture. When the liquid has disappeared from the surface gradually pour on more of the mixture of Alcohol and Water, using the same proportions as before, and continue the percolation until 2 pints of the Tincture are obtained. U. S. 1880. The U. S. 1870 preparation contained no Glycerin. MADE BY WATER-BATH PERCOLATION. Yellow Cinchona, in No. 50 powder, . 6 ounces av. Glycerin, 2 fl. ounces. Alcohol, I , rr ■ . , 1 • each sufficient to make . . 2 pints. Water, I Mix the Glycerin with 20 fl. ounces of Alcohol and 8 fl. ounces of Water, moisten the powder with 6 ounces of the mixture TINCTUR/E — TINCTURES. 901 and macerate in a closed vessel for 24 hours ; transfer it then to the water-bath percolator, pack firmly, pour upon it the remainder of the mixture and set in a warm place for 24 hours, then heat very moderately, and, after one hour, begin to per- colate. When the liquid has disappeared from the surface add through the percolator enough Alcohol and Water, mixed in the proportion of 2 measures of Alcohol to 1 measure of Water, to complete the percolation and make 2 pints of Tinc- ture. Lastly, after standing a few days, filter through paper. The Br. P. directs Red Cinchona Bark 4 ounces, Proof Spirit to make 20 fl. ounces, in the same manner as the U. S. The G. P. directs i part of Cinchona and 5 parts of diluted Alcohol, to be made by maceration. This is given as a tonic in doses of y 2 to 2 fl. drachms. 3469. Tinctura Cinchonae Composita. Compound Tincture of Cinchona — Huxhani s Tincture — Tinctura Chinee Composita. G. P. Red Cinchona, ... 10 parts or 3 ounces av. Bitter Orange Peel, . 8 parts or 2^ ounces av. Serpentaria, .... 2 parts or 260 grains. Glycerin 10 parts or 2^ fl. ounces. Alcohol, J each sufficient Water, ) to make . 100 parts or 2 pints. Mix the Glycerin with 80 parts or 28 fl. ounces of Alcohol and 10 parts or 3 fl. ounces of Water. Having mixed the Cin- chona, Orange Peel, and Serpentaria, reduce them to a fine (No. 60) powder, moisten the powder with 20 parts or 5 fl. ounces of the menstruum and macerate for 24 hours, then pack it firmly in a cylindrical glass percolator and gradually pour on the remainder of the menstruum. When the liquid lias disappeared from the surface gradually pour upon it enough of a mixture of Alcohol and Water, using the same propor- tions as before, and continue the percolation until 100. parts or 2 pints of Tincture are obtained. U. S. 1880. The U. S. 1870 formula was about the same, except that no Glycerin was used; this i-^ added to prevent the precipitation 902 TINCTUR/E — TINCTURES. of cincho-tannic acid and other constituents, which occurs when it is not employed. MADE BY WATER-BATH PERCOLATION. This may be made by water-bath percolation, with the ingredients as above, in the same manner as is directed for making Tincture Cinchona, preceding. The Br. P. formula is Red Cinchona Bark 2 ounces, Bitter Orange Peel I ounce, Serpentary y 2 ounce, Saffron 55 grains, Cochineal 28 grains, Proof Spirit to make 20 fl. ounces, by mac- eration and percolation. The G. P. directs, under the title Tinctura Chinee Composita, Cinchona 6 parts, Orange Peel 2 parts, Gentian 2 parts, Cinna- mon 1 part, diluted Alcohol 50 parts. This is also called Elixir Roborans. This Tincture is much used as a tonic and stomachic, the dose being ^ to 2 fl. drachms. 3470. Tinctura Cinnamomi. Tincture of Cinnamon. Cinnamon, in No. 40 powder, 10 parts or 2l/% ounces av. Alcohol, l each sufficient to Water, \ make . . . .100 parts or 2 pints. Mix Alcohol and Water in the proportion of 3 parts by weight (22 fl. ounces) of Alcohol to 2 parts (12 fl. ounces) of Water, and, having moistened the powder with 3 fl. ounces of the mixture, pack it in a conical percolator and gradually pour menstruum upon it until 2 pints of Tincture are obtained. U. S. 1880. MADE BY WATER-BATH PERCOLATION. Make a Tincture of the ingredients named above by water- bath percolation. The Br. P. directs Cinnamon Bark 2 x / 2 ounces av., Rectified Spirit to make 20 fl. ounces of Tincture. The G. P. directs 1 part of Cinnamon and 5 parts of diluted Alcohol. Tincture of Cinnamon is used as an aromatic and stimulant in doses of x / 2 to 1 teaspoonful. TINCTUR/E — TINCTURES. 903 3471. Tinctura Cocci. Br. Tincture of Cochineal. Cochineal, in powder, 2 x / 2 ounces av. Proof Spirit, 20 fl. ounces. Macerate for seven days in a closed vessel, with occasional agitation, strain, press, and add sufficient Proof Spirit to make 20 fl. ounces. 3472. Tinctura Colchici. Tincture of Colchicum. Colchicum Seed, in No. 30 powder, 15 parts or 4^ ounces av. Diluted Alcohol, sufficient to make 100 parts or 2 pints. Moisten the powder with 4 ounces of diluted Alcohol and macerate for 24 hours, then pack it in a cylindrical percolator and gradually pour diluted Alcohol upon it until 2 pints of Tincture are obtained. U. S. 1880. MADE BY WATER-BATH PERCOLATION. Colchicum Seed, in No. 30 powder, . Afi/% ounces av. Diluted Alcohol, sufficient to make . 2 pints. Make a Tincture by water-bath percolation in the same manner as is directed for Tincture Arnica Root (3440). The Br. P., under the title Tinctura Colchici Seminum {Sem- iuis /1, directs Colchicum Seed 2 l / 2 ounces av. with Proof Spirit to make 20 fl. ounces of Tincture. The (i. P. directs 1 part of Colchicum Seed with 10 parts of diluted Alcohol. This is used as an anti-rheumatic, the dose being 10 to 40 minims. 3473. Tinctura Colocynthidis. G. P. Tincture of Colocyuth. Colocynth, with the Seeds I part. Alcohol, 10 parts. Prepared by maceration. This is a bitter stomachic and cathartic, the d<>><- being 5 to 15 minims. 904 TINCTUR/E — TINCTURES. 3474. Tinctura Conii. Tincture of Conium — Tincture of Hemlock. The 1870 Pharmacopoeia directed Conium Leaves to be used in this preparation, but in the present revision Conium Leaves have been dismissed, the fruit only being officinal. Conium (fruit), in No. 30 powder, . 4^ ounces av. Diluted Hydrochloric Acid, . . . 1 fl. drachm. Diluted Alcohol, sufficient to make . 2 pints. Moisten the powder with 2 fl. ounces of diluted Alcohol, previously mixed with the diluted Hydrochloric Acid, and macerate for 24 hours, then pack it moderately in a conical percolator and gradually pour diluted Alcohol upon it until 2 pints of Tincture are obtained. U. S. 1880. MADE BY WATER-BATH PERCOLATION. Conium (fruit), in No. 30 powder, . 4^ ounces av. Diluted Hydrochloric Acid, . . . 1 fl. drachm. Diluted Alcohol, sufficient to make . 2 pints. Make a Tincture by water-bath percolation in the same manner as directed for making Tincture Arnica Root (3440). The Br. P. formula is Hemlock Fruit 2]/ 2 ounces, Proof Spirit to make 20 fl. ounces. This is a sedative, the dose being 20 to 60 minims. 3475. Tinctura Croci. Tincture of Saffron. Saffron, 10 parts or 3 ounces av. Diluted Alcohol, enough to make 100 parts or 2 pints. Moisten the Saffron with 3 ounces of diluted Alcohol and macerate for 24 hours, then pack it firmly in a cylindrical per- colator and gradually pour diluted Alcohol upon it until 100 parts or 2 pints of Tincture are obtained. U. S. 1880. This is designed to be made from the foreign Saffron {Crocus Sativus). Many American druggists do not keep this on account of its high price, but use in its place American Saffron or Safflower {CartJiamus Tinctorius), which much resembles it. TINCTURE — TINCTURES. 905 It may be made by water-bath percolation as directed for making Tincture Arnica Fiowers. The Br. P. directs Saffron i ounce with Proof Spirit to make 20 fl. ounces. The G. P. formula directs Saffron 1 part, diluted Alcohol 10 parts. Tincture of Saffron is an aromatic, used to add to other preparations and for its orange colors ; also given in doses of y 2 to 1 teaspoonful. 3476. Tinctura Cubebae. Tincture of Cubeb. Cubeb, in No. 30 powder, 10 parts or 3^ ounces av. Diluted Alcohol, sufficient to make 100 parts or 2 pints. Moisten the powder with 3 ounces of diluted Alcohol and macerate for 24 hours, then pack it firmly in a cylindrical per- colator and gradually pour diluted Alcohol upon it until 2 pints of Tincture are obtained. U. S. 1880. MADE BY WATER-BATH PERCOLATION. Cubeb, in No. 30 powder, .... 3>6 ounces av. Diluted Alcohol, sufficient to make . 2 pints. Make a Tincture by water-bath percolation in the same manner as directed for making Tincture Arnica Root 13440). The Br. P. directs 2^ ounces of Cubebs, in powder, with Rectified Spirit to make 20 fl. ounces of Tincture. As the medicinal properties of Cubebs are better soluble in a stronger alcoholic menstruum, this is the better formula. This is given as a stimulant to the mucous membrane in doses of y 2 to 2 fl. drachms. 3477. Tinctura Digitalis. Tincture of Digitalis {Fox Glove). Digitalis, recently dried, and in No. 60 powder, . 15 parts or 4?;; ounces av. Diluted Alcohol, sufficient to make ICO parts or 2 pints. 906 TINCTURE — TINCTURES. Moisten the powder with 5 fl. ounces of diluted Alcohol and macerate for 24 hours, then pack it firmly in a cylindrical per- colator and gradually pour diluted Alcohol upon it until 2 pints of Tincture are obtained. U. S. 1880. MADE BY WATER-BATH PERCOLATION. Digitalis, recently dried, in No. 50 powder, 4^5 ounces av. Diluted Alcohol, sufficient to make . . 2 pints. Make a Tincture by water-bath percolation in the same man- ner as is directed for making Tincture of Belladonna (3446). The Br. P. directs 2]/ 2 ounces av. of Foxglove Leaves with Proof Spirit to make 20 fl. ounces of Tincture. The G. P. directs I part of Digitalis and 10 parts of diluted Alcohol. This is given as an arterial sedative, the dose of the U. S. Tincture being 5 to 30 minims. 3478. Tinctura Ergotae. Br. Tincture of Ergot. Ergot, finely comminuted, 5 ounces av. Proof Spirit, 20 fl. ounces. Macerate the Ergot for 48 hours in 15 fl. ounces of the Spirit in a closed vessel, agitating occasionally, then transfer to a per- colator, and, when the fluid ceases to pass, continue the perco- lation with Proof Spirit until 20 fl. ounces are obtained. The dose is 5 to 30 minims. 3479. Tinctura Ferri Acetatis. Tincture of Acetate of Iron {Ferric Acetate). By weight. By measure. Solution of Acetate of Iron, 50 parts. 6y& fl. ounces. Alcohol, 30 parts. 5^ fl. ounces. Acetic Ether, 20 parts. 3% fl. ounces. Mix the Alcohol and Acetic Ether and gradually add the Solution of Acetate of Iron, taking care that the mixture remains cool. Keep the Tincture in glass stoppered bottles in a cool, dark place. U. S. 1880. riNCTURiE — TINCTURES. 907 rademacher's tincture of acetate of iron. This is much better known than the officinal Tincture. The formula is therefore given : Sulphate of Iron, pure 23 parts. Acetate of Lead 24 parts. Distilled Water, 48 parts. Good Vinegar 96 parts. Alcohol, 80 parts. Triturate the Sulphate of Iron and Acetate of Lead together in a Wedgewood mortar until a thick magma results, then add gradually the Water and Vinegar, and pour the whole into a flask or bottle, which is to be kept at a temperature of 30 to 40 C. (86° to 104 F.) for three days, with occasional agitation ; filter and let the filtrate stand for 30 days, occasionally shak- ing, in a wide-mouth bottle, only half filled, and loosely cov- ered with a plate of glass ; then add 80 parts of Alcohol and allow to stand ten days more in the same flask, and, finally, filter. The Br. P. formula is strong Solution Acetate of Iron 5 fl. ounces, Acetic Acid 1 fl. ounce, Rectified Spirit 5 fl. ounces. distilled Water 9 fl. ounces. Mix and add sufficient distilled Water to make the measure 20 fl. ounces. The dose is 5 to 30 minims. The G. P., under the title Tinctura Ferri Acetici sEtherea or Etherial Tincture of Acetate of Iron, is Solution Acetate of Iron 80 parts, Alcohol 12 parts, Acetic Ether 8 parts. 3480. Tinctura Ferri Chloridi. Tincture of Chloride of Iron — Tincture Muriate of Iron. By weight. Solution of Chloridi- of Iron 35 parts. Alcohol, 65 parts. Mix the Solution with the Alcohol and let it stand in a closely-covered vessel at least three months, then transfer it to glass-stoppered bottles. 17, S. 18S0. In making this Tincture by the formula of the [&80 Phar- macopoeia, if the articles used are of the standard strength, '.)( >8 TINCTURE — TINCTURES. the proportion will be about 8 fl. ounces of the Solution to 25 fl. ounces of Alcohol, but as the Solution of Chloride of Iron as bought is not always of the same specific gravity as the Pharmacopoeia directs, it is best to combine the ingredients by weight. The Br. P., under the title Tinctura Ferri Pcrchloridi, or Tincture Perchloridc of Iron, directs strong Solution of Per- chloride of Iron 5 fl. ounces, Rectified Spirit 5 fl. ounces, dis- tilled Water 10 fl. ounces, to be mixed and enough distilled Water to be added to make 20 fl. ounces. Tincture of Iron is one of the best known preparations of Iron, acting as a tonic and astringent. The dose is from 10 to 30 minims, which should be diluted and taken through a tube to prevent blackening the teeth. A so-called Tasteless Tincture of Iron is considerably used. See page 570. 3481. Tinctura Ferri Chlorati /Etherea. G. P. Ethereal Tincture Chloride of Iron — Spiritus Ferri Chlorati ALthereus — Liquor Anodynus Martiatus — Tinctura Ton ico-Nervina Bestuscheffi. Solution Chloride of Iron, 1 part. Ether, 2 parts. Alcohol, 7 parts. Mix them and expose in clear glass bottles to sunlight until colorless, then remove to a shady place and open them occa- sionally until the contents have again assumed a yellow color. This Tincture contains 1 per cent, of Iron. 3482. Tinctura Ferri Pomatia. G. P. Tincture of Ferrated Extract of Apples — Stahltropfen. Ferrated Extract of Apples, 1 part. Cinnamon Water, 9 parts. Dissolve and filter. This Tincture (which is more properly a solution) is much prescribed and used as a tonic in German practice. TINCTURE — TINCTURES. 909 3483. Tinctura Gallae. Tincture of Nutgall. Xutgall, No. 40 powder, . 20 parts or 6 l < ounces aw Glycerin, 10 parts or 2]/ x fl. ounces. Diluted Alcohol, sufficient to make 100 parts or 2 pints. Mix the Glycerin with 30 fl. ounces of diluted Alcohol, and, having moistened the powder with 4 ounces of the mixture, pack it in a conical glass percolator, then gradually pour upon it, first, the remainder of the mixture, and, afterward, diluted Alcohol, until 2 pints of Tincture are obtained. U. S. 1880. The Br. P. directs Galls 2^2 ounces with Proof Spirit to make 20 fl. ounces of the Tincture. The G. P., under the title Tinctura Gallarum, directs 1 part of Nutgalls with 5 parts of diluted Alcohol. This Tincture is given as an astringent in doses of ]4 to 2 fl. drachms. 3484. Tinctura Gelsemii. Tincture of Gelsemium {Yellozv Jasmin). Gelsemium (root), in No. 60 powder, 15 parts or 4^ ounces av. Alcohol, sufficient to make 100 parts or 2 pints. Moisten the powder with 10 parts or 3 fl. ounces of Alcohol and macerate for 24 hours, then pack it firmly in a cylindrical percolator and gradually pour Alcohol upon it until 100 parts or 2 pints of Tincture are obtained. U. S. 1880. MAIM'. BY WATER-BATH PERCOLATION. Gelsemium, in No. 60 powder, ... 4 ounces av. Alcohol, sufficient to make .... 2 pints. Moisten the powder with 3 ounces of Alcohol and pack firmly in the water-bath percolator, pour upon it a pint and a half <.f Alcohol and set in a warm place for (wo days, then heat very moderately, and, after one hour, begin to percolate, adding Alcohol to the drug and continuing the heat and per- colation until 2 pints <»f Tincture have passed. 910 TINCTUR.K — TINCTURES. A saturated Tincture is also prepared from the green root, which is highly esteemed. The Br. P. directs 2]/ 2 ounces of Gelsemium with Alcohol to make 20 fi. ounces of Tincture. Tincture of Gelsemium is employed as an arterial sedative, the dose being 10 to 30 miniums of the official Tincture, but much less of the green Tincture. 3485. Tinctura Gentianae. G. P. Tincture of Gentian. Gentian, 1 part. Diluted Alcohol, 5 parts Prepare a Tincture by maceration. The dose is a teaspoonful or more. 3486. Tinctura Gentianae Composita. Compound Tincture of Gentian. Gentian, ...... 8 parts or 2^2 ounces av. Bitter Orange Peel, . . 4 parts or i 1 /^ ounces av. Cardamom, 2 parts or 280 grains. Diluted Alcohol, suffi- cient to make . . . 100 parts or 2 pints. Mix the Gentian, Orange Peel, and Cardamom, and reduce them to a moderately coarse powder, moisten the powder with 3 ounces of diluted Alcohol and macerate for 24 hours, then pack it in a cylindrical percolator and gradually pour diluted Alcohol upon it until 2 pints of Tincture are obtained. U. S. 1880. This may be made with the same ingredients by water-bath percolation as directed for making Tincture Arnica Root. The Br. P. formula is Gentian \]/ 2 ounce av., Bitter Orange Peel y^ ounce av., Cardamom Seed ]^ ounce av., with Proof Spirit to make 20 fl. ounces of Tincture. Tincture of Gentian Compound is a bitter tonic, a popular remedy for dyspepsia and similar disorders. The dose is x / 2 to 2 teaspoonfuls. TINCTURiE — TINCTURES. 911 3487, Compound Tincture of Gentian, Improved. Gentian, in coarse powder 2 x / 2 ounces av. Cardamom, a fine powder, .... y 2 ounce av. Oranges, medium size, sweet, . . . Xo. 3. Alcohol, 1 pint. Water, sufficient to make .... 2 pints. Peel the Oranges, squeeze out the juice and mix it with 12 fl. ounces each of Alcohol and Water, chop the Orange Peel fine, mix it with the Gentian and Cardamom, and, having moistened the drugs with 3 ounces of the mixture, macerate for 24 hours in a closed vessel. Transfer it then to a percola- tor, pack moderately, pour upon it the remainder of the mix- ture and set in a warm place for two days, then begin to per- colate, adding to the drugs, after the liquid has disappeared from the surface, the remaining 4 ounces of Alcohol mixed with 4 ounces of Water, and continuing the percolation with Water, if necessary, until 2 pints of Tincture are obtained. Lastly, after standing a few days for the albuminous matter to separate, filter. This makes an excellent Compound Tincture of Gentian, of much better flavor than the official preparation. 3488. Tinctura Guaiaci. Tincture of Guaiac. Guaiac (resin), in coarse powder, 20 parts or 51^ ounces av. Alcohol, sufficient to make 100 parts or 2 pints. Mix the powder with a pint and a half of Alcohol and mac- erate for seven days in a closed vessel ; then filter through paper, adding through the filter enough Alcohol to make 2 pints of Tincture. U. S. 1880. MADE BY WATER-BATH PERCOLATION. Guaiac, in coarse powder, . . . . 5 j ^ ounces av. Alcohol, sufficient to make .... 2 pints. Mix the Guaiac with an equal bulk of coarse sand and agi- tate the mixture with a pint and a half of Alcohol in a wide-- 912 TINXTUR.1-: — TINCTURES. mouth bottle, cover the perforated diaphragm of the water- bath percolator with burlap or coarse cloth and pour the mixture upon it ; keep in a warm place for three days, then heat moderately, and, after one hour, begin to percolate, add- ing Alcohol to the drug when the liquid has disappeared from the surface, and continuing the heat and percolation until 2 pints of the Tincture are obtained. This Tincture is given as an anti-rheumatic and laxative in doses of J/? to i teaspoonful diluted. 3489, Tinctura Guaiaci Ammoniata. Ammoniatcd Tincture of Guaiac. Guaiac (resin), in coarse powder, 20 parts or 51^ ounces av. Aromatic Spirit of Am- monia, sufficient to make 100 parts or sufficient. The 1870 Pharmacopoeia directs the Guaiac to be macerated with the Aromatic Spirit of Ammonia for seven days and filtered. The 1880 Pharmacopoeia directs to mix the powder with a pint and a half of Aromatic Spirit of Ammonia and macerate for seven days in a closed vessel, then filter through paper, adding through the filter Aromatic Spirit of Ammonia until 2 pints of Tincture are obtained. The filter should be well covered during filtration to prevent evaporation of Ammonia. The Br. P. directs Guaiacum Resin, in powder, 4 ounces av., to be macerated with 15 fl. ounces of Aromatic Spirit of Am- monia for seven days with occasional agitation, then filtered and enough Alcohol added through the filter to make 20 fl. ounces. The dose is l / 2 to 1 fl. drachm diluted. Tincture of Guaiac, Alkaline. — An Alkaline Tincture of Guaiac, not official, but known as Detvees Tincture of Guaiac, is made with Guaiac Resin, in powder, 2 tr.ounces. Carbonate of Potassium 45 grains, Pimenta, in powder, 240 grains, Diluted Alcohol sufficient to make 16 fl. ounces. Digest two weeks. The dose is 1 to 2 teaspoonfuls. TINCTURE — TINXTURES. 913 3490. Tincturae Herbarum Recentium. Tinctures of Fresh Herbs. Under this heading the 1880 revision gives a general formula for making Tinctures from Fresh Herbs. The Fresh Herb, bruised or crushed, .... 50 parts or 16 ounces aw Alcohol (by weight), . . 100 parts or 3773 fl. ounces. Macerate the Herb with the Alcohol for 14 days, then express the liquid and filter. MADE BY WATER-P.ATII PERCOLATION. Tinctures of fresh herbs, flowers, barks, leaves, roots, etc., may be made by water-bath percolation by the following General Formula for Tinctures from Fresh Herbs, etc. The Fresh Herb, Bark, Flower, Leaf, or Root, 16 ounces av. Alcohol, sufficient to make .... 2 pints. Bruise, crush, cut, grate, or otherwise reduce the substance to the proper condition for exhaustion and pack it in the water-bath percolator, pour upon it a pint of Alcohol and set in a warm place for two days, then heat moderately, and, aft cl- one hour, begin to percolate, adding Alcohol to the drug ami continuing the heat and percolation until a pint and a half has passed; remove the drug from the percolator, express, ami, If the expressed liquid measures more than half a pint, evaporate it to that measure and add t<> the percolate; but if it measures less than half a pint, make up to that measure with Alcohol and add to the percolate. Lastly, after standing for a few days, filter through paper. The so-called "Green Tinctures," "Saturated Tinctures," "Specific Tincture-,," etc., may l»e made in this manner. A great variety of Tinctures are prepared from green plants in this manner. 914 TINCTUR/E — TINCTURES. 3491. Tinctura Humuli. Tincture of Hops — Tincture Lupuli. Br. Hops, No. 20 powder, . 20 parts or 6^ ounces av. Diluted Alcohol, sufficient to make ..... 100 parts or 2 pints. Moisten the powder with 12 fl. ounces of diluted Alcohol and macerate for 24 hours, then pack firmly in a cylindrical percolator and gradually pour diluted Alcohol upon it until 2 pints of Tincture are obtained. U. S. 1880. MADE BY WATER-BATH PERCOLATION. Hops, in No. 20 powder, 6}^ ounces av. Diluted Alcohol, sufficient to make . 2 pints. Make a Tincture by water-bath percolation in the same man- ner as directed for Tincture Belladonna. The Br. P., under the title Tinctura Lupuli, directs Hops 2 Y / 2 ounces av. with Proof Spirit to make 20 fl. ounces of Tincture. The dose of Tincture of Hops is ]/ 2 to 2 fl. drachms as a tonic and nervine. 3492. Tinctura Hydrastis. Tincture of Hydrastis (Golden Seal). Hydrastis, in No. 60 powder, 20 parts, or 6^ ounces av. Diluted Alcohol, sufficient to make 100 parts or 2 pints. Moisten the powder with 5 fl. ounces of diluted Alcohol and macerate for 24 hours, then pack it in a cylindrical percolator and gradually pour diluted Alcohol upon it until 2 pints of Tincture are obtained. U. S. 1880. This may be made by water-bath percolation as directed for Tincture Arnica Root (3440). The dose is a teaspoonful or more. TINCTURE — TINCTU RES. 915 3493. Tinctura Hyoscyami. Tincture Hyoscyamus {Henbane). Hyoscyamus Leaves, re- cently dried, in No. 60 powder, 15 parts or 4^ ounces av. Diluted Alcohol, sufficient to make 100 parts or 2 pints. Moisten the powder with 4 fl. ounces of diluted Alcohol and macerate for 24 hours, then pack it firmly in a cylindrical per- colator and gradually pour diluted Alcohol upon it until 2 pints of Tincture are obtained. U. S. 1880. MADE BY WATER-BATH PERCOLATION. Hyoscyamus Leaves, in No. 50 powder, 4^ ounces av. Diluted Alcohol, sufficient to make . 2 pints. Make a Tincture by water-bath percolation in the same man- ner as is directed for Tincture Belladonna (3446). The Br. P. directs Hyoscyamus 2.y 2 ounces av. with Proof Spirit to make 20 fl. ounces of Tincture. This is given as an anodyne and sedative. Dose, y 2 to 1 fl. drachm. 3494. Tinctura Ignatiae. Tincture of Ignatia. Ignatia, in No. 60 powder, 10 parts. AlCOhol, j , rr ■ . ' - each sufficient. Water, ) This new official formula directs the powder to be exhausted with Alcohol and Water, mixed in the proportion of 8 parts of the former to 1 of the latter. A portion of the Tincture thus obtained is then assayed to ascertain the quantity of dry Extract of Ignatia which it contains, and from this the quan- tity of extract which the whole percolate represents is to be estimated. Menstruum is then to be added, if required, so that 1 part of the dried extracl may be contained in too parts of tin Tincture. For the detailed formula see Tincture of Nux Vomica, which is made in the same manner. 916 TINCTURiE — TINCTURES. A more simple method of making it is as follows : Extract Ignatia, Alcoholic, dry, . . 60 grains. Alcohol, 14 fl. ounces. Water, \ l / 2 fl. ounces. Mix the Alcohol and Water and dissolve the Extract in the mixture. This is the same strength as the officinal formula. 3495. Tinctura Iodi. Tincture of Iodine. Iodine, 8 parts or 495 grains. Alcohol, • 92 parts or 1 pint. Dissolve the Iodine in the Alcohol. U. S. 1880. This is. quite different from the Br. P. formula, which is Iodine y 2 ounce av., Iodide of Potassium ]/ 2 ounce av., dis- solved in Rectified Spirit 20 fl. ounces. The dose is 5 to 20 minims. It corresponds nearly with the U. S. 1870 Tincture of Iodine Compound. The G. P. formula, under the title Tinctura Jodi, is Iodine 1 part, Alcohol 10 parts. The U. S. and G. P. Tinctures are seldom given internally but are used for outward application as an absorbent, alone or combined with other substances. When given, the dose is 1 to 3 minims. 3496. Tinctura Iodinii Composita. Compound Tincture of Iodine. This was official in the U. S. 1870 Pharmacopoeia, and is still called for. Iodine, 240 grains. Iodide of Potassium 480 grains. Alcohol, a pint. Dissolve the Iodine and Iodide of Potassium in the Alcohol. This Tincture is omitted in the present Pharmacopoeia. Its only advantage was that it could be combined with Water without precipitation. TINCTURE — TINCTURES. 917 3497. Tincture Ipecacuanhae. G. P. Tincture of Ipecac. Ipecac, . . 1 part. Diluted Alcohol, 10 parts. Make a Tincture by maceration or percolation. The dose is 15 to 30 minims. 3498. Tinctura Ipecacuanhae et Opii. Tincture Ipecac and Opium — Tinctura Dover i. Deodorized Tincture of Opium, . . 15 fi. ounces. Fluid Extract of Ipecac, .... \y 2 fl. ounces. Diluted Alcohol, sufficient. Evaporate the deodorized Tincture of Opium to 12^ fl. ounces. When it has become cold, add to it the Fluid Extract of Ipecac, filter the mixture and pass through the filter enough diluted Alcohol to make 15 fl. ounces. U. S. 1880. This Tincture represents Dover's powder in a liquid form, 10 minims containing the strength of 1 grain each of Opium and Ipecac. The dose is 10 to 15 minims. 3499. Tinctura Jaborandi. Br. Tincture of Jaborandi — Tincture of Pilocarpus. Jaborandi, in No. 40 powder, .... 5 ounces av. Proof Spirit, 20 fl.ounces. Macerate the Jaborandi for 48 hours in 1 5 fl.ounces of the Spirit in a closed vessel, agitating occasionally, then transfer to a percolator and, when the fluid ceases to pass, continue the percolation with the remaining 5 ounces of Spirit. After- wards subject the contents of the percolator to pressure, filter the produ< t, mix the liquids, and add suffii ienl Proof Spirit to make 20 fl.ounces. This may also be made by water-bath percolation as directed for Tincture of I'.clladonna. Dose, y 2 to l tl. drachm. 918 TINCTURE — TINCTURES. 3500. Tinctura Jalapae. Br. Tincture of Jalap. Jalap, in powder, 2 1 /, ounces av. Proof Spirit, 20 fl. ounces. Make a Tincture by maceration, percolation, etc., as directed for the preceding. This Tincture was official in the 1870 U. S. P., the formula being Jalap 6 tr.ounces, Alcohol 2 parts to Water 1 part, a sufficient quantity to make 2 pints. The dose, as a purgative, is ]/ 2 to 2 fl. drachms. 3501. Tinctura Kino. Tincture of Kino. Kino, 10 parts or 360 grains. Glycerin, 15 parts or 1 fl. ounce. Alcohol, J each sufficient Water, \ to make . . 100 parts or y 2 pint. Mix the Glycerin with 60 parts or 6 fl. ounces of Alcohol, and 15 parts or 1 ^ fl. ounces of Water, rub the Kino in a mortar, adding gradually 30 parts or 3 fl. ounces of menstruum until a smooth paste is made ; transfer this to a bottle, add the remainder of the menstruum and macerate for 24 hours, occa- sionally shaking the bottle, then filter through paper, adding through the filter enough of a mixture of Alcohol and Water, made in the proportion of 5 measures of Alcohol to 1 measure of Water, to make half a pint of the Tincture. U. S. 1880. Keep the Tincture in well-stopped bottles. The great trouble with Tincture of Kino is its tendency to gelatinize. This formula, if properly followed, is supposed to overcome this difficulty. The Br. P. formula is Kino 2 ounces, Glycerin 3 fl. ounces, Distilled Water 5 fl. ounces, Rectified Spirit 12 fl. ounces. Mac- erate for 7 days in a closed vessel, with occasional agitation, filter, and add sufficient Rectified Spirit to make 20 fl. ounces. Tincture of Kino is an astringent, given in doses of x / 2 to 2 fl.drachms. TINCTUR^E — TINCTURES. 919 3502. Tinctura Krameriae. Tincture of Krameria {Rhatany). Rhatany (Root), in No. 40 powder, 20 parts or 6 l /± ounces aw Diluted Alcohol, sufficient to make 100 parts or 2 pints. Moisten the powder with 6 ounces of diluted Alcohol and macerate for 24 hours, then pack it in a cylindrical percolator and gradually pour diluted Alcohol upon it until 2 pints of Tincture are obtained. U. S. 1880. MADK BY WATER-BATH PERCOLATION. Rhatany, in No. 40 powder, . . . 6% ounces av. Diluted Alcohol, sufficient to make . 2 pints. Make a Tincture by water-bath percolation in the same manner as is directed for Tincture Arnica Root (3440). The Br. P. directs Rhatany Root 2% ounces av. with Proof Spirit to make 20 fl. ounces. The G. P., under the title Tinctura RatanJiice, directs Kra- meria I part, diluted Alcohol 5 parts, to be made by maceration. Tincture of Rhatany is an astringent, given in doses of ^ to 2 fl. ounces. 35°3- Tinctura Laricis. Br. Tincture of Larch. Larch Bark, in No. 40 powder, . . 2^ ounces aw Rectified Spirit 20 fl. ounces. Macerate the Larch Bark for 48 hours in 15 fl. ounces of the Spirit, then percolate, adding Rectified Spirit through tin- per- colator to make 20 fl. ounces of the Tincture. This is the Tincture of the European Larch, Abies Larix. The close is 20 to 30 minims. 3504. Tinctura Lavandulae Composita. Compound Tincture of Lavender > ('. S. 1880 Spirit us Lav- endula Composita, U. S. 1870 Spirit of Lavender. This preparation, which was formerly classed with Spirits, has been very properly transferred t" the Tinctures in the 920 TINCTURE — TINCTURES. present Pharmacopoeia. As the difference is so slight between the 1870 and 1880 preparation, the latter formula only is given. Oil of Lavender, ... 8 parts or 2 fl. drachms. Oil of Rosemary, ... 2 parts or 30 minims. Cinnamon, in coarse powder, 18 parts or 230 grains. Cloves, 4 parts or 52 grains. Nutmeg, 10 parts or 128 grains. Red Saunders, coarse powder, 8 parts or 103 grains. Alcohol (by weight), . . 680 parts or 23 fl. ounces. Water, 270 parts or 7^5 fl. ounces. Diluted Alcohol, suffi- cient to make . . 1000 parts or 2 pints. Dissolve the Oils in the Alcohol and add the Water, crush the Nutmeg in a mortar, mix with it the Cinnamon, Cloves, and Red Saunders, and reduce the mixture by grinding to a coarse powder; moisten the mixture with a sufficient quantity of the Alcoholic solution of the Oils, pack it firmly in a cylin- drical percolator, gradually pour upon it the remainder of the Alcoholic solution and, afterward, diluted Alcohol until 1000 parts or 2 pints of the Tincture are obtained. U. S. 1880. The Br. P. formula is so similar that it need not be repeated. Tincture of Lavender Compound is an agreeable stomachic and aromatic. The dose is Vi to 2 fl. drachms. 35°5- Tinctura Limonis. Br. Tincture of Lemon Peel. Fresh Lemon Peel, cut small, . . . 2^ ounces av. Proof Spirit, 20 fl. ounces. .Macerate for seven days in a closed vessel, with occasional agitation, strain, press, and filter; then add sufficient Proof Spirit to make 20 fl. ounces. It might with advantage be made much stronger. This is used for flavoring and given as an aromatic stimu- lant in doses of V 2 to 2 fl. drachms. TINCTURE — TINCTURES. 921 3506. Tinctura Lobeliae. Tincture of Lobelia. Lobelia (herb), in No. 40 powder, 20 parts or 6%. ounces av. Diluted Alcohol, sufficient to make 100 parts or 2 pints. Moisten the powder with 6 fl. ounces of diluted Alcohol and macerate for 24 hours, then pack it firmly in a cylindrical per- colator and gradually pour diluted Alcohol upon it until 2 pints of Tincture are obtained. U. S. 1880. MADE BY WATER-BATH PERCOLATION. Lobelia (herb), in No. 40 powder, . 6^ ounces av. Diluted Alcohol, sufficient to make . 2 pints. Make a Tincture by water-bath percolation as directed for making Tincture Arnica Root (3440). The Br. P. directs Lobelia 2]/ 2 ounces av. with Proof Spirit to make 20 fl. ounces of Tincture. The G. P. directs 1 part of Lobelia with 10 parts of diluted Alcohol. The dose is 5 to 15 minims. The dose of the U. S. and Br. preparations is from 10 to 30 minims. 3507. Tinctura Lobeliae ^Etherea. Br. Ether ia I Tincture of Lobelia. Lobelia, in coarse powder, .... 2 l /i ounces av. Spirit of Ether (2971) 20 fl. ounces. Macerate for seven days in a closed vessel, with occasional agitation, then strain, press, filter, and add sufficient Spirit of Ether to make 20 fl. ounces. Dose, 10 to 30 minims. 3508. Tinctura Lupulinae. Tincture of Lupuliu. This was official in the 1S70 I'. S. I'., a- follows : Lupujin p;; ounces aw Alcohol, sufficient to make .... 2 pints. 922 TINCTURE — TINCTURES. Pack the Lupulin in a narrow cylindrical percolator and gradually pour Alcohol upon it until 2 pints of Tincture are obtained. Although this Tincture was omitted from the 1880 Phar- macopoeia, it will be frequently called for. It may be made by water-bath percolation in the same manner as other Tinctures. This must not be mistaken for the Br. official Tinctura Lupuli or Tincture of Hop. See Tinctura Humuli. 3509. Tinctura Matico. Tincture of Matico. Matico, in No. 40 powder, . 10 parts or 3 ounces av. Diluted Alcohol, sufficient to make 100 parts or 2 pints. Moisten the Matico with 3 ounces of Diluted Alcohol and macerate for 24 hours, then pack it firmly in a cylindrical per- colator and gradually pour diluted Alcohol upon it until 2 pints of Tincture are obtained. U. S. 1880. MADE BY WATER-BATH PERCOLATION. Matico, in No. 40 powder, 3 ounces av. Diluted Alcohol, sufficient to make . . 2 pints. Make a Tincture by water-bath percolation in the same manner as directed for making Tincture Belladonna (3446). 3510. Tinctura Moschi. Tincture of Musk. Musk 10 parts or 337 grains. Alcohol, 45 parts or 4}i fl. ounces. Water, 45 parts or 3^ fl. ounces. Diluted Alcohol, sufficient to make, 100 parts or 8 fl. ounces. Rub the Musk in a mortar, first with a little of the Water, until a smooth mixture is made, and then with the remainder of the Water ; transfer the whole to a bottle, add the Alcohol, and macerate the mixture for seven days, occasionally shaking the bottle, then filter through paper, adding through the filter TINCTUR.K — TINCTURES. 923 enough diluted Alcohol to make the Tincture measure half a pint. U. S. 1880. As good grain Musk (which is to be used in this prepara- tion) is worth from §25.00 to $35.00 per ounce, it will be advis- able to touch this official very lightly. The G. P. directs Musk 1 part, diluted Alcohol, Water, each 25 parts, made as above. 351 1. Tinctura Myrrhae. Tincture of Myrrh. Myrrh, in No. 30 powder. 20 parts or 5^ ounces av. Alcohol, sufficient to make 100 parts or 2 pints. Mix the powder with a pint and a half of Alcohol and mac- erate for seven days in a closed vessel, then filter through paper, adding through the filter enough Alcohol to make 2 pints of Tincture. U. S. 1880. MADE BY WATER-BATH PERCOLATION. Myrrh, in No. 30 powder, . . . . $y 2 ounces av. Alcohol, sufficient to make .... 2 pints. Make a Tincture in the same manner as directed for making Tincture Guaiac by water-bath percolation. The Br. P. directs Myrrh, in coarse powder, 2 l /> ounces av. with Rectified Spirit to make 20 fi. ounces of Tincture. The G. P. formula is Myrrh 1 part, Alcohol 5 parts, made by maceration. 3512. Tinctura Nucis Vomicae. Tincture of Nux J "omica. \ m ■-. Vomica, in No. 60 powder 20 parts or 5^ ounces av. Alcohol, / 1 re ■ each sufficient. Water, * Mix Alcohol and Water in the proportion «>f s parts by weighl (19 tl. .Mm. .-si of Alcohol to 1 pari 12 fl.ounces) <>f Water; moisten the powder with 21 1 parts or 6 fl.ounces of the mixture .m. 1 macerate for 24 hours, then pack it firmly in a cylindrical percolator and gradually pour menstruum upon it 024 TINCTURE — TINCTURES. until the Nux Vomica is exhausted. Reserve the first 90 parts of the percolate, evaporate the remainder to 10 parts, and mix with the reserved portion. Of this Tincture (which should measure about 2 pints), take any convenient number of parts, and, by means of a water-bath, evaporate to dryness ; weigh the resulting extract, and, from its weight, calculate the quan- tity of dry extract contained in the 100 parts of Tincture; then dissolve the dried extract in the remainder of the Tinc- ture, and add enough of the above menstruum to make the product weigh so many parts that each 100 parts of Tincture shall contain 2 parts of dry extract. Lastly, mix thoroughly, and filter through paper. U. S. 1880. The Tincture thus prepared should represent about 20 parts of Nux Vomica in 100 parts, and would, therefore, measure about 2 pints. Although the U. S. 1880 formula has the advantage of mak- ing a preparation of definite strength, it will be seldom used by the majority of druggists, because of the trouble and nicety of calculation required to obtain the percentage of dry extract. The 1880 preparation is only about jj, the strength of the 1870, which was 8 tr.ounces of the drug to make 2 pints of Tincture, and the process of macerating with gentle heat, which was formerly employed, was of great advantage. A simple method of making this Tincture of the required strength is as follows : Extract of Nux Vomica, dry, ... 60 grains. Alcohol, 14 fl. ounces. Water, i}4 fl. ounces. Mix the Alcohol and Water and dissolve the extract in the mixture. The following formula will be found most expedient for exhausting the Nux Vomica, and is sufficiently accurate for all practical purposes: MADE BY WATER-BATH PERCOLATION. Nux Vomica, in No. 60 powder, . . ^ l / 2 ounces av. ' \ each sufficient to make . 2 pints. Water, ) r TIXCTUK.E — TINCTURES. 925 Mix Alcohol and Water in the proportion of 19 fl. ounces of Alcohol to 2 fl. ounces of Water, and, having moistened the Nux Vomica with 8 ounces of the mixture, macerate it for 24 hours in a closed vessel in a warm place, then pack firmly in the water-bath percolator, pour upon it a pint and a half of menstruum and set in a warm place for two days ; then heat moderately, and, after one hour, begin to percolate, adding menstruum to the drug, and continuing the heat and percola- tion until 2 pints of Tincture are obtained. The dose of this Tincture is 5 to 20 minims. The Br. P. formula is Extract of Nux Vomica 133 grains, distilled Water 4 fl. ounces, Rectified Spirit sufficient to make 20 fl. ounces. One fl. ounce contains 1 grain of the alkaloids of Nux Vomica. The dose is 10 to 20 minims. The G. P., under the title Tinctura Strychnia directs Nux Vomica I part, diluted Alcohol io parts, to be made into a Tincture by maceration. The dose is 5 to 15 minims. 3513. Tinctura Opii. Tincture of Opium {Laudanuni). As the U. S. 1870 and 1880 preparations are both used, the formulas are given : 1870. 1880. Powd. Opium, 2-;^ ounces av. 10 parts or 3^ ounces av. Water, ... 16 fl. ounces. 40 parts or 1 2 ; 4 11. ounces. Alcohol, . . 16 fl. ounces. 40 parts or 15^ fl.ounces. Diluted Alco- hol, sufficient to make . . 2 pints. 100 parts or 2 pints. < For 1X70 direction see U. S. 1'. [870.) Rub the Opium in a mortar with the Water, previously heated to the temperature of 90 C. i \>>.\ F.), until a smooth mixture is made, and macerate for \i hours, then add the Alcohol, mix thoroughly, and transfer the whole to a conical dator; return to the percolator the firsl portion of perco- late until it bei omes clear, and, when the liquid ceases to drop, gradually pour on diluted Alcohol, continuing the percolation until 2 pints of Tincture are obtained. I . S. [880. 926 TINCTURiE — TINXTURES. Although powdered Opium is directed to be used in this as well as all other preparations of Opium, it has not heretofore been used by one druggist in a hundred. Two causes have tended to bring about this result ; first, the higher price of powdered Opium, and, second, its liability to sophistication, as it has been formerly furnished ; but now that powdered Opium, bearing the assay label of reliable houses, may be obtained, this excuse is no longer tenable. No process for making Tincture of Opium will be found so efficient and economical as the process of water-bath percolation. MADE BY WATER-BATH PERCOLATION. (1870 U. S. P. Standard.) Powdered Opium, 2^ ounces av. Water, I pint. Alcohol, 1 pint. Diluted Alcohol, sufficient to make . 2 pints. Mix the Opium with the Water previously heated to boiling, and macerate for 12 hours, then, having covered the perforated diaphragm of the water-bath percolator with coarse cloth, pour the mixture upon it; heat to about 8o° C. (176 F.) for two hours, then add the Alcohol and, after half an hour, begin to percolate, adding diluted Alcohol to the drug when the liquid has all disappeared from the surface, and continuing the heat and percolation until 2 pints of Tincture are obtained. Lastly, after standing a day or two, filter through paper. If moist Opium is used instead of powdered, 3^ ounces av. may be used instead. It should be cut in small pieces and rubbed with hot water in a mortar to a uniform pasty mass, then macerated for 10 or 12 hours in a warm place, the Alco- hol added, and percolated either by the ordinary process or by water-bath percolation. If it is desired to make Tincture of Opium of the 1880 strength by water-bath percolation, simply substitute the quan- tities mentioned in the 1880 formula and proceed as directed. Tincture of Opium is given as an anodyne in doses of 10 to 30 minims. It is also used extensively for external application in liniments, etc. TIXCTUR.E — TINCTURES. 927 The Br. P. directs Opium, in powder, I y' 2 ounce with Proof Spirit sufficient to make 20 fl. ounces. Made by maceration. Dose, 5 to 40 minims. The G. P., under the title Tinctura Opii Simplex, directs Opium, in powder, 1 part, diluted Alcohol 5 parts, Water 5 parts. To be made by maceration. 3514. Tinctura Opii Acetata. Acctatcd Tincture of Opium. This preparation was official in the U. S. P. 1870, and is now occasionally called for. Powdered Opium 2 tr.ounces. Distilled Vinegar, 12 fl. ounces. Alcohol, 8 fl. ounces. Rub the Opium with the distilled Vinegar, then add the Alcohol and, having macerated for seven days, express and filter through paper. U. S. 1870. This Tincture is no longer official, and would not be here noticed except that it is sometimes called for, and the formula is convenient for reference. It has no advantages not pos- sessed by Vinegar of Opium, and two preparations so similar arc unnecessary. 3515. Tinctura Opii Ammoniata. Br. Ammoniated Tincture of Opium. Opium, in powder 100 grains. Saffron, cut small 180 grains. Benzoic Acid [80 grains. Oil of Anise 1 fl. drachm. Strong Solution of Ammonia 4 fl.ounces. Rectified Spirit, [6 fl.ounces. Macerate for seven days in a well-closed vessel, with occa- sional agitation, then strain, press, filter, and add sufficient Rectified Spirit to make 20 fl.ounces. The dose is 30 to 60 minims. 928 TINCTURE — TINCTURES. 3516. Tinctura Opii Benzoica. G. P. Benzoatcd Tincture of Opium — Paregoric Elixir. Opium, in powder I part. Oil of Anise, 1 part. Camphor, 2 parts. Benzoic Acid, 4 parts. Diluted Alcohol 192 parts. Prepare a Tincture by maceration. This is similar to the U. S. Camphorated Tincture of Opium, known as Paregoric, but contains a larger proportion of Cam- phor and Benzoic Acid. 3517. Tinctura Opii Camphorata. CampJwrated Tincture of Opium — Paregoric. 4 parts or 56 grains. 4 parts or 56 grains. 4 parts or 56 grains. 4 parts or 1 fl. drachm. 40 parts or 1 fl. ounce. Powdered Opium, Benzoic Acid, . Camphor, . . Oil of Anise, Glycerin, ... Diluted Alcohol, sufficient to make 1000 parts or 2 pints. Add 28 fl. ounces of diluted Alcohol to the other ingredients contained in a suitable vessel and macerate for seven days, frequently stirring, then filter through paper in a well-covered funnel and pass enough diluted Alcohol through the filter to make 2 pints. U. S. 1880. Sixty grains of powdered Extract of Liquorice added makes a darker and more desirable color. The following formula will be found very convenient for making Paregoric quickly or extemporaneously : RAPID PROCESS FOR MAKING PAREGORIC. Tincture of Opium (1870), . . . . i$4 fl. ounces. Benzoic Acid, 60 grains. Extract of Liquorice, powdered, . . 60 grains. Camphor, 40 grains. TINCTURE — TINCTURES. 929 Oil of Anise I fl. drachm. Glycerin, I fl. ounce. Alcohol 15 fl. ounces. Water 15 fl. ounces. Dissolve the Benzoic Acid, Camphor, and Oil of Anise in the Alcohol, mix the Glycerin, Tincture of Opium, and Water, and dissolve the Extract of Liquorice in the mixture; then mix the two solutions and, after standing a few hours, filter through paper. The dose is 20 to 60 minims or more. Tincturd CampJwrce Composita, Br., and Tinctura Opii Ben- zoica, G. P., are corresponding but dissimilar preparations. 3518. Tinctura Opii Crocata. G. P. Tincture of Opium and Saffron — Sydenham's Laudanum. Opium, in powder, 30 parts. Saffron, 10 parts. Cloves, 2 parts. Cinnamon, 2 parts. Diluted Alcohol, 150 parts. Water, 150 parts. Prepare a Tincture by maceration. The dose is 5 to 20 minims. This is the same strength of Opium as the official Tincture Opium. 3519. Tinctura Opii Deodorata. Deodorized Tincture of Opium. 1 870. 1 880. Powd. Opium, 2^ ounces av. 10 parts or ,V 4 ounces av. Ether, . . . 8 fl. ounces. 20 parts or 8j^ fl.ounces. Alcohol, . . 8 fl.ounces. 20 parts or 8 fl.ounces. Water, sufficient to make . . 2 pints. [ 00 parts or 2 pints. kul. the Opium in a mortar with [ 2 ounces of Water, grad- ually added, until thoroughly softened, and macerate for [2 hours; then express, and repeal the operation twice, using the 930 TINCTUR/E — TINCTURES. same amount of Water each time ; mix the expressed liquids, evaporate the mixture to 3^ ounces and, when it has cooled, shake it repeatedly with the Ether in a bottle, When the etherial solution has separated, by standing, pour it off and evaporate the remaining liquids until all traces of Ether have disappeared ; mix the residue with a pint of Water and filter the mixture through paper. When the liquid has ceased to pass, add enough Water through the filter to make the filtered liquid measure a pint and a half. Lastly, add the Alcohol and mix them. U. S. 1880. The directions for making are essentially the same in both revisions. The proportion of Opium is the same as in the ordinary Tincture of Opium. A method of making Deodorized Tincture of Opium, in which Petrolatum is used instead of Ether for separating the objectionable properties, has recently been proposed by E. Rother (A. J. P., February, 1883). If this process is rightly and carefully conducted it will be attended with good results, but it requires more care and attention than druggists usually bestow upon it. The following formula will be found the most expedient and economical of any that has been proposed. The Opium may be exhausted either by water-bath percolation, or as the Phar- macopoeia directs, but the water-bath process is to be preferred. 3520. Deodorized Tincture of Opium. Fenner's Improved Process. (1870 U. S. P. Standard.) Powdered Opium 2}( ounces av. Alcohol 8 fl. ounces. Gasoline (Petroleum Ether), 8 fl. ounces. Water, sufficient to make 2 pints. Mix the Opium with 12 ounces of hot Water and macerate for 12 hours; having covered the perforated diaphragm of the water-bath percolator with burlap or coarse cloth, pour the mixture upon it and heat it for four hours to about 85 C. (185 F.), then begin to percolate slowly, adding Water to ihe drug, and continuing the heat and percolation until a pint and a half has passed, or until the drug is exhausted ; evaporate this percolate to 6 fl. ounces and, when cool, mix it in a quart bottle with the Gasoline and shake it violently and frequently during 12 hours; then, having inserted a small plug of cotton TINCTURE — TINCTURES. 931 in the neck, and stopped the lower orifice of a glass funnel with a cork, pour the mixture in it and allow it to stand an hour to separate ; then loosen the cork so that the lower stratum of liquid may be drawn off, and allow the tarry matter and the supernatant Gasoline to remain in the funnel ; evapo- rate from the drawn-off liquid thus obtained (which is the depurated solution of Opium) all traces of Gasoline, mix it with a pint of Water and filter, pass- ing through the filter sufficient Water to make a pint and a half of the fil- tered liquid ; to this add the Alcohol and, after standing a few days, filter through paper. As thus prepared the Tincture contains the full strength of the Opium, deprived of its noxious and objectionable properties. The Gasoline is more efficient than the Ether for the purpose required and is entirely inexpensive. If it is desired to make this Tincture of the 1880 strength, substitute the proportions of the 1880 formula. 3521. Tinctura Pimpinellae. G. P. Tincture of Pimpinel. Pimpinel Root, . . . ; 1 part. Diluted Alcohol, 5 parts. Make a Tincture by maceration. 3522. Tinctura Physostigmatis. Tincture of Calabar Beau. Physostigma, in No. 40 powder 10 parts or 2^ ounces av. Alcohol, sufficient to make 100 parts or 2 pints. Moisten the powder with 3 ounces of Alcohol and macerate for 24 hours, then pack it firmly in a cylindrical percolator and gradually pour Alcohol upon it until 2 pints of Tincture are obtained. U. S. [880. MADE BY w Al ER-BA III PERI 1 >] A.TION. Calabar Bean, in No. 40 powder. . . 2\, ounces aw Alcohol, sufficient to make .... 2 pints. Make a Tincture by water-bath percolation in the same manner a- i- dire* ted lor making Tinctura I relsemii 1 3484 1. This is a narcotic sedative, used for neuralgia, etc. The dose is 10 to 30 minims. 932 TINCTURE — TINCTURES. 3523. Tinctura Podophylli. Br. Tincture of Podophyllum {Resin). Resin of Podophyllum, 160 grains or 1 part. Rectified Spirit, ... 20 fi. ounces or 54.68 fl. parts. Dissolve and filter. It contains 1 grain of the Resin in 1 fl. drachm. The dose is 15 to 60 minims. Care should be taken not to be misled by the title of this formula as an unofficial Tincture of Podophyllum (Mandrake Root) is sometimes used. 3524. Tinctura Pyrethri. Tincture of Pyrethrum (Pellitory). Pyrethrum, in No. 40 powder, 20 parts or 5^ ounces av. Alcohol, sufficient to make 100 parts or 2 pints. Moisten the powder with 5 ounces of Alcohol and macerate for 24 hours, then pack it firmly in a cylindrical percolator and gradually pour Alcohol upon it until 2 pints of Tincture are obtained. U. S. 1880. MADE BY WATER-BATH PERCOLATION. Pellitory, in No. 40 powder, ... 5^ ounces av. Alcohol, sufficient to make .... 2 pints. Make a Tincture by water-bath percolation in the same manner as is directed for making Tinctura Cimicifugae (3467). The Br. P. directs Pellitory Root 4 ounces with Rectified Spirit to make 20 fi. ounces of the Tincture. 35 2 5- Tinctura Quassiae. Tincture of Quassia. Quassia, in No. 40 powder,. to parts or 3 ounces av. Diluted Alcohol, sufficient to make 100 parts or 2 pints. Moisten the powder with 3 ounces of diluted Alcohol and macerate for 24 hours, then pack it firmly in a cylindrical per- colator and gradually pour diluted Alcohol upon it until 2 pints of Tincture are obtained. U. S. 1880. TINCTURE — TIN'CTURES. 933 MADE BY WATER-BATH PERCOLATION. Quassia, in No. 40 powder, .... 3 ounces av. Diluted Alcohol, sufficient to make . 2 pints. Make a Tincture by water-bath percolation in the same man- ner as is directed for making- Tincture Arnica Root. The Br. P. directs Quassia Wood, in chips, ^ ounce av. to be macerated for seven days with Proof Spirit sufficient to make 20 fi. ounces. It is only about one third the strength of the U. S. preparation. Tincture of Quassia is a bitter stomachic, the dose of the U. S. being 15 to 60 minims. 3526. Tinctura Quininae. Br. Tincture of Quinine. Hydrochlorate of Quinine, 160 grains. Tincture of Orange Peel, 20 fl. ounces. Dissolve the Hydrochlorate of Quinine in the Tincture with the aid of a little heat, then allow the solution to remain in a closed vessel for three days, shaking it occasionally, and after- wards filter. The dose is l / 2 to 2 fl. drachms, a fl. drachm containing 1 grain of the Quinine salt. A Tincture may be made from any other salt of Quinine by using the same quantity of the salt with 20 fl. ounces of Tincture of Orange Peel, or by dissolving 40 minims of Oil of Orange in 10 fl. ounces of Alcohol, and adding the Quinine salt, dissolving, then adding 10 fl. ounces of Water. 3527. Tinctura Quininae Ammoniata. Br. Ammoniated Tincture of Quinine, Sulphate of Quinine 160 grains. Solution of Ammonia J 1 ., fl. ounces. Proof Spirit 1 7 ' _• fl.ounces. Dissolve the Quinine salt in the Proof Spirit by the aid of a little heat and add the Solution of Ammonia. A fl. drachm contains 1 grain of the Quinine salt. The dose is x / z to 2 fl. drachms. 934 TINCTU RJE — TINCTURES. 3528. Tinctura Rhei. Tincture of RJmbarb. Rhubarb, 12 parts or 3^ ounces av. Cardamom, in fine powder, 2 parts or 270 grains. Diluted Alcohol, sufficient to make 100 parts or 2 pints. Mix the Rhubarb and Cardamom and reduce the mixture to a moderately coarse (No. 40) powder, moisten the powder with 4 ounces of diluted Alcohol and macerate for 24 hours, then pack it firmly in a cylindrical percolator and gradually pour diluted Alcohol upon.it until 2 pints of Tincture are obtained. U. S. 1880. This may also be made from the same ingredients, by water- bath percolation, as directed for making Tincture Arnica Root. The Br. P. directs Rhubarb Root, in No. 20 powder, 2 ounces av., Cardamom, Coriander, Saffron, each, bruised, % ounce av., with Proof Spirit to make 20 fl. ounces. Tincture of Rhubarb is given as a stomachic in doses of 1 to 2 fl. drachms, and as a purgative in doses of y 2 to 1 fl. ounce. 3529. Tinctura Rhei Aquosa. G. P. Aqueous Tincture of Rhubarb. Rhubarb, 100 parts. Borate of Sodium (Borax), 10 parts. Pure Carbonate of Sodium, 10 parts. Water, 900 parts. Cinnamon Water, 150 parts. Alcohol, 90 parts. Heat the Water to boiling, pour it upon the coarsely-cut Rhubarb (freed from powder), the Borate of Sodium and Car- bonate of Potassium, and allow them to digest in a closed vessel for a quarter of an hour, then add the Alcohol and set the mixture aside for one hour. Now strain the mixture through a woolen cloth and express gently the undissolved portion. Finally, add the Cinnamon Water in the proportion of 150 parts to 850 parts of the strained liquid. The dose of this Tincture is 1 to 4 fl. drachms as a laxative. TINCTURE — TINCTURES. 035 3530. Tinctura Rhei Aromatica. Aromatic Tincture of Rhubarb — Spiced Tincture of Rhubarb. Rhubarb 20 parts or 6^4 ounces av. Cinnamon 4 parts or 1 ^ ounces av. Cloves, 4 parts or 1 ' + ounces av. Nutmeg 2 parts or 2j' : grains. Diluted Alcohol, suffi- cient to make . . . 100 parts or 2 pints. Mix the Rhubarb, Cinnamon, Cloves, and Nutmeg and. reduce the mixture to a moderately coarse powder, moisten the powder with 15 parts or 5 ounces of diluted Alcohol and macerate for 24 hours, then pack it firmly in a cylindrical per- colator and gradually pour diluted Alcohol upon it until 100 parts or 2 pints of Tincture are obtained. U- S. 1880. MADE BY WATER-BATH PERCOLATION. From the same ingredients as directed make a Tincture by water-bath percolation in the same manner as directed for making Tinctura Aurantii Amari 13445). This is given for diarrhoea of children especially, acting first as a purgative, then as an astringent. The dose is a teaspoon- ful to a tablespoonful. 3531. Tinctura Rhei Dulcis. Sweet Tincture of Rhubarb. Rhubarb 8 parts or 2^4 ounces av. Liquorice (Root), . . 4 parts or [jS^ ounces av. Anise 4 parts or 1 ' + ounces av. Cardamom 1 part or [36 grains. Diluted Alcohol, suffici- ent to make . . . [00 parts or 2 pints. Mix the Rhubarb, Liquorice, Anise, and Cardamom ard reduce them to a moderately coarse (No. 40) powder, mi the powder with 15 parts or 5 ounces of diluted Alcohol and ni.K erate for 2 1 hour., then pat k it firmly in .1 cylindrical per- colator and gradually pour diluted Alcohol upon it until 100 or 2 pints of Tincture are obtained. I . S. [880. 936 TINCTUR.E — TINCTURES. MADE BY WATER-BATH PERCOLATION. From the same ingredients as directed make a Tincture by water-bath percolation in the same manner as directed for making Tincture of Arnica Root (3440). This is a weak, pleasant Tincture of Rhubarb, generally given to children in doses of a teaspoonful to a tablespoonful. 3532. Tinctura Rhei et Sennae. Tincture of Rhubarb and Senna. Although this Tincture has been dismissed from the present revision of the U. S. Pharmacopoeia it is still considerably used. It was formerly known as Warner s Gout Cordial, and has been an officinal preparation for many generations. Why it should be dismissed and other much less frequently used preparations retained is not apparent. The following is the formula: Rhubarb, in moderately coarse powder, 480 Senna, in moderately coarse powder, . Coriander, in moderately coarse powder, Fennel, in moderately coarse powder, Liquorice Extract, in moderately coarse powder, . . . • Raisins, deprived of their seeds, . . Diluted Alcohol, Macerate for seven days, express, and filter through paper. The dose is a teaspoonful as a laxative. 3533- Tinctura Rhei Vinosa. G. P. Vinous Tincture of Rhubarb. This preparation should properly be included with the Wines instead of the Tinctures, but is classed as above in the G. P. Rhubarb, 8 parts. Orange Peel, 2 parts. Cardamom, 1 part. Sherry Wine, 100 parts. Sugar, a sufficient quantity. l8o grains. 20 grains. 60 grains. 60 grains. 30 grains. 6% ounces av. 3 pints. TINCTURE — TINCTURES. 937 Make a Tincture by maceration and expression and in the filtered liquid obtained dissolve one seventh of its weight of Sugar. The dose is 2 to 4 fl. drachms or more. 3534. Tinctura Sabinae. Br. Tincture of Savine. Savine Tops, coarsely powdered, . . 2)4 ounces av. Proof Spirit 20 fl. ounces. Make 20 fl. ounces of Tincture by maceration and per- colation. 3535- Tinctura Sanguinariae. Tincture of Sanguinaria (Bloodroof). Sanguinaria, in Xo. 60 powder, 15 parts or 4^5 ounces av. Alcohol, / , «• . . • each sufficient. Water, j Mix Alcohol and Water in the proportion of 2 parts < by weight), or 24 fl. ounces of Alcohol with 1 part (by weight |, or 10 fl. ounces of Water, moisten the powder with 3 ounces of the mixture and macerate for 24 hours, then pack it firmly in a cylindrical percolator and gradually pour the menstruum upon it until 2 pints of Tincture are obtained. (J. S. [880. maim: by w.vi er-bath perc< >la rn in. Bloodroot, in No. 60 powder, . . . 4^3 ounces av. Alcohol 24 fl.ounces. Water IO tl. ounces. Diluted Alcohol, sufficienl to make 2 pints. Mix the Alcohol and Water, moisten the powder with 4 ounces of the mixture and macerate for 24 hours in a closed vessel, transfer it to the water-bath percolator, pack firmly, poui upon it the remainder of the menstruum and set in .1 warm place for two days, then lu-.it moderately and, after one hour, begin to percolate; when the liquid has all disappeared from the surface of the drug add sufficienl diluted Alcohol, 938 TIXCTUR.E — TINCTURES. through the percolator, to make the Tincture measure 2 pints. Lastly, after standing a few days, filter through paper. This is given as a stimulating expectorant and tonic in doses of 10 to 30 minims. 3536. Tinctura Saponis Viridis. Tincture of Green Soap. Green Soap, 65 parts or 10 ounces av. Oil of Lavender, ... 2 parts or 3 fl. drachms. Alcohol, sufficient to make 100 parts or 1 pint. Mix the Soap and the Oil of Lavender with 33 parts or 6 fl. ounces of Alcohol and let the mixture macerate until the Soap is dissolved, then filter through paper, adding Alcohol through the filter until 100 parts or 1 pint of Tincture is obtained. U. S. 1880. This preparation may be quickly made by heating the ingre- dients together in the water-bath percolator until the Soap is dissolved and then drawing off the liquid. 3537- Tinctura Scillae. Tincture of Squill. Squill, in No. 30 powder, . 15. parts or 4^ ounces av. Diluted Alcohol, sufficient to make 100 parts or 2 pints. Moisten the powder with 6 ounces of diluted Alcohol and macerate for 24 hours, then pack it moderately in a conical percolator and gradually pour diluted Alcohol upon it until 2 pints of Tincture are obtained. U. S. 1880. MADE BY WATER-HATH PERCOLATION. This may be made by water-bath percolation in the same manner as Tincture of Belladonna. The Br. P. directs Squill 2]/ 2 ounces av., Proof Spirit to make 20 fl. ounces. Made as the U. S. preparation. The G. P. directs Squill 1 part, diluted Alcohol 5 parts, made by maceration. Tincture of Squill is diuretic and expectorant. The dose is 10 to 30 minims. TINCTURE — TINCTURES. 939 353^- Tinctura Senegae. Br. Tincture of Senega. Senega Root, in Xo. 40 powder, . . 2 l / 2 ounces av. Proof Spirit, to make 20 fl. ounces. Macerate the Senega for 48 hours in 15 fl. ounces of the Spirit, percolate and add Spirit through the percolator to make 20 fl. ounces of Tincture. It may also be made by water-bath percolation. This is a tonic expectorant. The dose is ^ to 2 fl. drachms. 3539- Tinctura Sennas. Br. Tincture of Senna — Compound Tincture of Senna. Senna, broken small 2]/ 2 ounces av. Raisins, freed from seeds 2 ounces av. Caraway Fruit (Seeds), bruised, . . l / 2 ounce av. Coriander Fruit 1 Seeds 1, bruised, . x /> ounce av. Proof Spirit, to make 20 fl. ounces. Macerate the ingredients for 48 hours in 15 fl. ounces of the Spirit, then percolate, adding sufficient Spirit through the per- colator to produce 20 fl. ounces of Tincture. This may also be made by water-bath percolation in the same manner as is directed for Tincture Belladonna. This preparation was formerly known as Elixir Salutis. It is an excellent laxative in doses of a tablespoonful or more. 3540. Tinctura Serpentariae. Tincture of Scrpcntaria — Tincture of Serpeutary. Serpentaria, in No. 40 powder, io parts or 3 ounces av. Diluted Alcohol, sufficient to make 100 parts or 2 pints. Moisten the powder with 3 ounces. .f diluted Alcohol and macerate for 24 hour-, then pack it firmly in a cylindrical per- colator and gradually pour diluted Alcohol upon it until 2 pint- of Tincture are obtained. U.S. [880. 940 TINCTUR/E — TINCTURES. MADE BY WATER-BATH PERCOLATION. 'With the same ingredients make a Tincture by water-bath percolation as directed for making Tincture of Arnica Root (3440). The Br. P. directs Serpentary 2]/ 2 ounces, Proof Spirit to make 20 fl. ounces. Made by maceration and percolation as directed in the preceding. The dose is J / 2 to 2 fl. drachms as a stimulant and diaphoretic. 3541. Tinctura Sumbul. Tincture of Sumbul. ^ Sumbul, in No. 30 powder, 10 parts or 2^ ounces av. Alcohol, sufficient to make 100 parts or 2 pints. Moisten the powder with 10 parts or 3 fl. ounces of Alcohol and macerate for 24 hours, then pack it firmly in a cylindrical percolator and gradually pour Alcohol upon it until 100 parts or 2 pints of Tincture are obtained. U. S. 1880. MADE BY WATER-BATH PERCOLATION. Sumbul, in No. 30 powder, .... 2^ ounces av. Alcohol, sufficient to make .... 2 pints. Make a Tincture in the same manner as directed for making Tincture of Gelsemium. The Br. P. directs Sumbul 2]/ 2 ounces av. with Rectified Spirit to make 20 fl. ounces of Tincture. This is used as a nervine in doses of 10 to 30 minims. 3542. Tinctura Tolutana. Tincture of Tolu. U. S. 1870. Balsam of Tolu, 3^ ounces av. Alcohol, 2 pints. Macerate the Balsam with the Alcohol until it is dissolved, then filter through paper. This Tincture contains a larger proportion of Tolu than the U. S. 1880 preparation, and should be used when it is desired to make Syrup of Tolu by the U. S. 1870 formula. TINCTURiE — TINCTURES. 941 U. S. I 88c. Balsam of Tolu, 2^ ounces av. Alcohol, sufficient to make .... 2 pints. Add the Balsam of Tolu to. 30 fl. ounces of Alcohol and macerate until dissolved, then filter through paper, adding through the filter enough Alcohol to make 2 pints. Both the 1870 and 1880 formulas are given, as the former is still used for making the former official Syrup of Tolu. This Tincture may be quickly made by the aid of heat. The Balsam and the Alcohol may be put together in a bottle and macerated in a water-bath until the Balsam is dissolved. The Br. P. directs Balsam of Tolu 2y 2 ounces av. with suf- ficient Rectified Spirit to make 20 fl. ounces of Tincture. The dose is from 20 to 40 minims. 3543- Tinctura Valerianae. Tincture of Valerian. Valerian, in No. 60 powder, 20 parts or 6 ounces av. Alcohol, ) each sufficient to Water, ) make .... 100 parts or 2 pints. Mix Alcohol and Water in the proportion of 2 parts (by weight) or 24 fl. ounces of Alcohol to 1 part or 10 fl. ounces of Water; moisten the powder with 15 parts or 5 ounces of the mixture and macerate for 24 hours, then pack it firmly in a cylindrical percolator and gradually pour menstruum upon it until 100 parts or 2 pints of Tincture are obtained. U. S. 1880. MADE BY WATER-BATH PERCOLATION. Valerian, in No. 50 powder 6 ounces av. Alcohol, / Water, I Mix Alcohol and Water as above and make a Tincture by water-bath percolation in the same manner as directed for making Tincture Calumba. The Br. P. directs Valerian Root 2]/> ounces av. with Proof Spirit to make 20 fl. ounces of the Tincture by maceration and percolation. each sufficient to make . . 2 pints. 942 TIXCTUR.E — TINCTURES. The G. P. directs Valerian i part with diluted Alcohol 5 parts, to be made by maceration. Tincture of Valerian is given as a nervine, the dose being 1 to 2 fl. drachms. 3544. Tinctura Valerianae Ammoniata. Ammoniated Tincture of Valerian. Valerian, 20 parts or 6 ounces av. Aromatic Spirit of Ammonia, sufficient to make . . . 100 parts or 2 pints. Moisten the powder with 5 ounces of Aromatic Spirit of Ammonia and macerate for 24 hours in a closed vessel, then pack it firmly in a cylindrical glass percolator and gradually pour Aromatic Spirit of Ammonia upon it until 2 pints of Tincture are obtained. U. S. 1880. The Br. P. directs Valerian Root 2]/ 2 ounces av. with Aro- matic Spirit of Ammonia to make 20 fl. ounces of Tincture by maceration. This is used as a stimulant and nervine, the dose being 30 to 60 minims. 3545. Tinctura Valerianae ^therea. G. P. Etkerial Tincture of Valerian. Valerian, 1 part. Spirit of Ether, 5 parts. Prepare a Tincture by maceration. The dose is 20 to 60 minims. 3546. Tinctura Vanillae. Tincture of Vanilla. Vanilla, cut small and bruised, . 10 parts or 3 ounces av. Sugar, in coarse powder, ... 20 parts or 6 ounces av. Alcohol, ) each sufficient to Water, \ make 100 parts or 2 pints. Mix Alcohol and Water in the proportion of 2 parts (by weight) or 24 fl. ounces of Alcohol to I part or 10 fl. ounces of Water, macerate the Vanilla in 50 parts or 1 pint of this mix- TINCTURE — TINCTURES. 943 ture for 12 hours, then drain off the liquid and set it aside. Transfer the Vanilla to a mortar, beat it with the Sugar into a uniform powder, then pack it in a percolator and pour upon it the reserved liquid; when this has disappeared from the sur- face gradually pour on menstruum and continue the percola- tion until 100 parts or 2 pints of Tincture are obtained. U. S. 1880. MADE BY WATER-BATH PERCOLATION. Vanilla, cut small and bruised, ... 3 ounces av. Sugar, granulated 6 ounces av. Alcohol, I each sufficient to make _ _ 2 ints W ater, * Mix Alcohol and Water in the proportion of 24 fl. ounces of Alcohol to 10 fl. ounces of Water, moisten the Vanilla with 3 ounces of the mixture and macerate in a closed vessel for 24 hours, transfer it to a mortar and beat it thoroughly with the Sugar until it is reduced to a coarse powder, pack this very firmly in the water-bath percolator, pour upon it about a pint and a half of the menstruum and set in a warm place for two days, then heat very moderately and, after one hour, begin to percolate, adding the menstruum to the drug and continuing the heat and percolation until 2 pints of Tincture are obtained. Lastly, after standing a few days, filter through paper. This Tincture may be used as a flavoring extract but is stronger than is usually sold for that purpose. Formula' for flavoring extracts of Vanilla will be found on pages 419 and 420. 3547. Tinctura Veratri Viridis. Tincture of Veratrum Viride [American Hellebore?) Veratrum Viride, in No. 60 powder 50 parts or n'_. ounces av. Alcohol, sufficient to make 100 pails or 2 pints. Moisten the powder with 5 ounces of Alcohol and macerate for 24 hours, then pack it firmly in a cylindrical percolator and gradually pour Alcohol upon it until 2 pints of Tincture are obtained. V . S. [8 The dose is 3 to 10 minims. 944 TINCTURE — TINCTURES. MADE BY WATER-BATH PERCOLATION. Veratrum Viride, in No. 50 powder, 14^ ounces av. Alcohol, sufficient to make .... 2 pints. Make a Tincture by water-bath percolation in the same man- ner as is directed for making Tincture of Aconite Root (3432). This Tincture is made to take the place of Norwood's Tinc- ture of Veratrum Viride, which has become popular on account of its reliability. The original Norwood's Tincture is made from the green root of the American Hellebore and is probably superior to any preparation made from the dried root. This Tincture may be prepared from the green root in the same way as is directed for making Tinctures Herbarum Recentium, which see. The Br. P. formula directs green Hellebore, Rhizome, in No. 40 powder, 4 ounces av. with Rectified Spirit sufficient to make 20 fi. ounces of Tincture, by maceration and percolation. (Although this is called Tincture of Green Hellebore, the adjec- tive relates to the color, and not the green or recent root, as is directed for making Norwood's Tincture. See above.) This is only about one third the strength of the U. S. prep- aration. The dose is 5 to 20 minims. The G. P. formula is White Hellebore 1 part, diluted Alco- hol 10 parts, being only about one sixth as strong as the U. S. and one half as strong as the Br. Tincture of Veratrum is used as an arterial sedative in fevers, delirium, etc. 3548. Tinctura Zingiberis. Tincture of Ginger. As there is considerable difference in the U. S. 1870 and 1880 preparations, both are given. 1870. 1880. Ginger, in No. 40 powder, . . 8^ ounces av. 20 parts or 5^ ounces av. Alcohol, suffici- ent to make . 2 pints. 100 parts or 2 pints. Moisten the Ginger with 2 ounces of Alcohol and macerate for 24 hours, then pack it firmly in a cylindrical percolator and TINCTUR/E — TINCTURES. 945 gradually pour Alcohol upon it until 2 pints of Tincture are obtained. U. S. 1880. MADE BY WATER-BATH PERCOLATION. (1880 U. S. P. Standard.) Ginger, in Xo. 40 powder 5.^ ounces av. Alcohol, sufficient to make .... 2 pints. Moisten the Ginger with 4 ounces of Alcohol and pack firmly in the water-bath percolator, pour upon it a pint and a half of Alcohol and set in a warm place for two days, then heat very moderately and, after one hour, begin to percolate slowly, adding Alcohol to the drug and continuing the heat and percolation until 2 pints of Tincture are obtained. The Alcohol remaining in the drug after percolation may be recovered by distillation. The Br. P. gives two formulas, one of the same title as the U. S., which is made with Ginger, Rhizome, 2)^ ounces av., with Rectified Spirit sufficient to make 20 fl. ounces, made by maceration and percolation. The other is called Tinctura Zin- gibcris Forticr or Strong Tincture of Ginger, and is made with Ginger 10 ounces av., percolated with sufficient Rectified Spirit to make 20 fl. ounces of Tincture. The G. P. directs Ginger 1 part, diluted Alcohol 5 parts. Tincture of Ginger is a warm stimulant, the dose being from 10 to 60 minims of the LJ. S. 1880 preparation. Unofficial Tinctures. The 1 Tinctures are those official in the leading pharmacopoeias ; besides these are many other Tinctures which are or have been popular, and which are more or less called for, the principal ones Wring made by the formulae which fol- low, which are arranged in classes as much as possible to avoid repel ition : SIMPLE TINCTURES. 3550. Tinctures Containing 10 per cent, of the Drug, be made by the following general general formula: Take of the drug, in powderoi thepropei fineness, 1 part or 1 ounce. The menstruum, ;i sufficient quantity to make to parts or io fl.ounceSi 946 TINCTUR/E — TINCTU RES. Moisten the drug with a portion of the menstruum sufficient to cover it and macerate for 24 hours in a warm place, then transfer to a water-bath percolator, add sufficient menstruum to well cover it and heat moderately ; after one hour begin to percolate, adding more of the menstruum and con- tinuing the percolation slowly until 10 parts or 10 rl. ounces are obtained. The ordinary process of cold percolation may be employed but does not pro- duce so satisfactory preparations. Some Tinctures are best prepared by maceration altogether. They are designated with a *. The following Tinctures are prepared after this formula and represent about 10 per cent, of the drug : UNOFFICIAL TINCTURES — TEN PER CENT. Tincture Prepared From. 3551 3552 3553 3554 3555 3556 3557 3553 3559 356o 356i 3562 3563 3564 3565 3566 3567 3568 356q Ailanthus * Ambergris Balm Gilead or Poplar Buds.. * Balsam Copaiba -'Balsam Fir Canella Chamomile (Anthemis) Cocculus Indicus(F ish Berries) Conium Delphinum (Staphisagria). . . . *Euphorbium *Galbanum Geranium (Cranesbill) Gold Thread (Coptis Trif.) . . Horse Chestnut *Lactucarium *Oxgall Pareira Brava Rhododendon (Laurel) Bark Buds Balsam Balsam Bark Flowers. . . . Fruit Leaves Seed Gum Gum Root Root Bark Insp. Juice. Inspissated . Rhizome . . . Leaves Diluted Alcohol Alcohol Alcohol Alcohol Alcohol Diluted Alcohol Diluted Alcohol Alcohol Diluted Diluted Diluted Diluted Diluted Diluted Diluted Diluted Alcohol. Alcohol. Alcohol. Alcohol. Alcohol. Alcohol. Alcohol. Alcohol. Alcohol. Alcohol. Yz to 2 fi.drs. For perfume. Yz to 1 ti.dr. 1 to 2 fi.drs. 1 to 2 fi.drs. 1 to 4 fi.drs. Yz to 2 fl.drs. 2 to 20 m. Yz to 1 fl.dr. External. External. 1 to 3 fi.drs. Yz to 2 fi.drs. Yz to 1 fl.dr. Yz to 1 fl.dr. 20 to 60 m. r to 2 fl.drs. 1 to 2 fl drs. Yz to 1 fl.dr. 3570. Tinctures Containing 15 per cent, of the Drug. These may be made by the following general formula : Take of the drug, in proper fineness for percolation 2 parts or 2 ounces av. The menstruum, sufficient to make . . .14 parts or 14 fl. ounces. Moisten the drug with a portion of the menstruum sufficient to cover it and macerate for 24 hours in a warm place, then transfer it to the water-bath percolator, add menstruum to cover it, heat moderately and, after one hour, begin to percolate, adding menstruum to the drug and continuing the perco- lation until 14 parts or 14 fl. ounces of the percolate is obtained. These may be made by ordinary percolation, but the product is not so sat- isfactory. Some preparations are better made by maceration than percola- tion ; such are designated with a *. TIXCTUR/E — TINCTURE; 947 UNOFFICIAL TINCTURES— FIFTEEN PER CENT Tincture Prepared From. 3571 3572 3573 3574 3575 3576 3577 3578 3579 35SO 3581 35S2 3583 3584 3585 3^S6 'Amber Blessed Thistle (Carduus)... . Blue Cohosh (Caulophyllum). Cloves, Carophylles Cochineal* (Coccus) Dracontium (Skunk Cabbage) Galangal (Catarrh Root) 'Guarana Hedge Hyssop (Cratiola). . . . Hellebore ■ Monesia (Chrysophyllum). . . . Musk Seed (Ambrette) Pulsatilla (Anemone) Rhus Toxicodend. (Pois. Oak) Vittie-Vayr Zedoaria Resin Root Flow, heads Whole Root Rhizome . .. Extract. . . . Plant Root Extract. . . . Seed Plant Plant Root Root Alcohol Alcohol Alcohol Alcohol Diluted Diluted Diluted Diluted Diluted Diluted Diluted 1 Hinted Diluted Diluted Diluted Diluted Alcohol. Alcohol. Alcohol. Alcohol. Alcohol. Alcohol. Alcohol . Alcohol. Alcohol. Alcohol. Alcohol. Alcohol. y z to 1 fl.dr. r to 2 fl.drs. 1 to 2 fl.drs. 1 to 2 fl.drs. Coloring. 1 to 4 fl.drs. y z to r fl.dr. 1 to 2 fl.drs. 1 to 2 fl.drs. y z to I fl.dr. y 2 to 2 fl drs. '_. to 1 fl.dr. 10 to 40 m. 5 to 40 m. 15 to 30 m. V, to 1 fl.dr. 3588. Tinctures Containing- 20 per cent, of the Drug - . These may be made by the following general formula : Take of the drug, in proper fineness for percolation 3 parts or 3 ounces av. The menstruum, sufficient to make . .15 parts or 15 ll. ounces. Moisten the drug with a portion of the menstruum sufficient to cover it and macerate for 24 hours in a warm place, then transfer to the water-bath per- colator, add menstruum sufficient to well cover the drug, heat moderately and, after one hour, begin to percolate, adding menstruum to the drug and continuing the percolation until 15 parts or 15 ll. ounces of the percolate is obtained. These may be made by ordinary cold percolation but the product is not so satisfactory. Some preparations are better made by maceration than perco- lation ; such are designated with a *. UNOFFICIAL TINCTURES — TWENTY PER CENT. 3589 359° 359' 3592 3593 3594 3595 359" 3597 Tincture Prepared From. Alkanet or Aucfausa Root Ucohol Coloi IDg Angostura r.ark I Hinted Alcohol . 1 to 3 B.drs. Araiia Spinosa (Prickly Elder) Bark Dilated Alcohol. 10 to 60 m. Arbor Vita (Thuja) Fresh twigs. . Alcohol i to 4 tl.ilrs. Aspidosperma (Quebracho).. . Bark Alcohol 1 to 2 ll.drs. ^Balsam Peru Balsam Alcohol 5 to 30 m. Baptisia (Wild Indigo) Root \lcohol I 5 to DO m. Blue Flag (Iris Versicolor).. .Root Alcohol 5 to 15 m. Boldo I Leaves A lcohol 51040m. 948 TINCTUR.E — TINCTURES. UNOFFICIAL TINCTURES — TWENTY PER CENT.— Continued. Tincture Prepared From. 359SJ Castor Oil Beans (Ricinus). . .Fruit j Alcohol 1 to 2 fl.drs. 3599 Contrayerva Root Alcohol ' l / 2 to 1 fl.dr. 3600 1 Corydalis (Turkey Corn) .... Tubers Diluted Alcohol.:^ to 2 fl.dr. 3601 Coto Bark Alcohol 15 to 75 m. 3602 Croton Seed Fruit I Alcohol 5 to 15 m. 3603 Culver's Root (Leptandra). . .jRoot Diluted Alcohol. ^ to 2 fl.drs. 3604 1 Elecampane Root Diluted Alcohol. l / 2 to 2 fl.drs. 3605 Erigeron (Fleabane) [Plant Diluted Alcohol. 1 to 2 fl.drs. 3606' Eucalyptus [Leaves Alcohol 1 to 2 fl.drs. 3607 Guaiacum Wood Wood Diluted Alcohol . 1 to 2 fl.drs. 360S Kamala, Rottlera Glands Diluted Alcohol. 1 to 2 fl.drs. 3609 * Mastic I Resin Alcohol For cement. 3610 Matico Leaves Diluted Alcohol. 1 to 2 fl.drs. 361 1 Orris (Iris Florentina) Rhizome . . . .jDiluted Alcohol. Perfume. 3612 Phytolacca or Poke 'Berries or root Diluted Alcohol. 20 to 60 m. 3613 *Red Gum Gum Alcohol 20 to 40 m. 3614 Rose (Red Rose) Petals Diluted Alcohol. Flavoring. 3615 Rosemary Tops Sp. of Rosemary Flavoring. 3616 Saponaria or Quillaya Bark Diluted Alcohol. Emulsions. 3617 *Scammony j Resin Alcohol , l / 2 to 1 fl.dr. 3618 Stillingia [Root Diluted Alcohol. 10 to 40 m. COMPOUND AND UNCLASSIFIED TINCTURES. 3619. Tincture Absinthium Compound — Swedish.— Blessed Thistle, Orange Berries, Galangal Root, each l / 2 ounce aw. Wormwood 1 ounce, diluted Alcohol sufficient to make 16 fl.ounces. Dose, 1 to 3 A. drachms. 3620. Tincture Acetate of Copper, Rademacher's.— Acetate of Cop- per in crystals, 154 grains. Dissolve in warm Water 4 flounces and add 2^ fl.ounces of Alcohol. Dose, 2 to 5 minims. 3621. Tincture of Aloes, Alkaline — Swedish. — Aloes y 2 ounce, Liquor- ice Extract \y 2 drachms. Cinnamon Water 8 ounces, diluted Alcohol 8 fl.ounces, Carbonate of Sodium 1 ounce. Digest and strain. Dose, 1 to 4 fl. drachms. 3622. Tincture Amber Alkaline. — Rub 2 ounces of Amber with Car- bonate of Potassium sufficient to make a soft, pasty mass, dry this and digest it in 16 ounces of Alcohol for 7 days, then filter. Dose, 20 to 30 drops. 3623. Tincture Ammonia Compound. — Mastic 120 grains, Alcohol 9 fl.ounces, digest until dissolved, add Oil of Lavender 14 drops, filter and mix well with 20 fl.ounces stronger Water of Ammonia. This is used as an antacid, antispasmodic, and stimulant. Aqua Lucia or Eau de Luce is made by adding to this 4 drops Oil of Amber. This is given and applied for snake bites, stings of insects, etc. The dose is 10 to 20 drops in water. TINCTURE — TINCTURES. 949 3624. Tincture Ammonio-Chloride of Iron. — Chloride of Iron and Am- monium i ounce, distilled Water and diluted Alcohol, each 5 fl. ounces. Dis- solve. Dose 20 to 60 minims. 3625. Tincture Antiscorbutic — (Paris Codex). — Fresh Horseradish Root 8 ounces, Black Mustard Seed 4 ounces, Muriate of Ammonia 2 ounces, diluted Alcohol 17 fl. ounces, Compound Syrup of Scurvygrass iS tl. ounces. Macerate 10 days. Dose, 1 to 2 teaspoonfuls. 3626. Tincture Ants — Tint turn Formicarum. — This was formerly offi- cial in the Ph. G. and was prepared from ants recently collected, cleaned, and bruised, 2 parts or ounces, Alcohol 3 parts or ounces, by weight. Macerated 8 days. 3627. Tincture Astringent —Dr. Copeland's.— Catechu % ounce, Myrrh y 2 ounce, Peruvian Bark % ounce, Balsam Peru 1 % drachm, Spirit of Horse- radish 1% ounce, Alcohol 12 fl. ounces. Mix, digest, and, after standing, fil- ter. This is used for spongy gums, etc. 3628. Tincture Bloodroot Acetous— Tinctura Sanguinarice Acetata Composita. — This is an Eclectic preparation, called also Acetous Emetic. Bloodroot, Lobelia. Skunk Cabbage Root, each 2 ounces, distilled Vinegar 2 pints, Alcohol 2 ll.ounces. Macerate and percolate the drugs with the Vine- gar and add the Alcohol. In small doses it is an excellent expectorant; in doses of a teaspoonful it is an tmetic. Repeat if necessary. 3629. Tincture Bloodroot Compound — Tinctura Sanguinarice Compos- ita. — This is made the same as the above except that diluted Alcohol is used instead of Vinegar. The uses and dose are the same. 3630. Tincture Cactus — Tincture of Night Blooming Cereus. — The fresh (lowers and stems of Cactus Grandiflora cut in small pieces and bruised, 5 ounces, Alcohol. 1 pint. Macerate for two weeks with occasional agitation, then filter. A Saturated Tincture maybe made by preparing the fresh (low- ers as directed and adding sufficient Alcohol to just cover them. This is usually sold as fluid Extract of Cactus. The dose of the weaker Tincture is 5 10 10 drops for heart disease, etc. 3631. Tincture Caulophyllum Compound — Blue Cohosh Compound Amer. Disp. Blue Cohosh 2 ounces. Ergot 1 ounce, Water Pepper (Smart- 1 ounce, I >il of Savin 30 minims, Alcohol sufficient to make 24 ll.ounces of I in< line. Macerate or percolate. This is an EmmenagOgue, given in doses of 15 drops to 1 H.drachm. 3632. Tincture Cimicifuga Compound — Black Cohosh Compound Amer. Disp. This is prepared by mixing Tincture of Black Cohosh 4 parts. Tincture of Bloodroot 1 parts, and Tincture of Poke Rool 1 pari, it is used for Rheumatism, et< , the dose being 10 to 50 minims. 3633. Tincture Cinchona Ammoniated— This is made by percolating <.r macerating Cinchona 2 ounces with Aromatic Spirit of Ammonia sufficient to make 16 ll.ounces. The dose is '_. to 1 teaspoonful. 950 TINCTUK.E — TINCTURES. 3634. Tincture Cochineal Ammoniated. — Cochineal %. ounce, Water of Ammonia % ounce. Alcohol 8 fl.ounces. Macerate and filter. Used for whooping cough, etc. Dose, 5 to 10 drops. 3635. Tincture Cockroaches — linctura Blattcc. — This is prepared from dried Cockroach, in No. 60 powder, 2 ounces aw, Alcohol 10 fl.ounces, by maceration and percolation., The dose is 20 to 30 minims. 3636. Tincture Colchicum Seed Compound.— Colchicum Seed, in fine powder, 2 ounces, Black Cohosh, in fine powder, 3 ounces, Diluted Alcohol sufficient to make 2 pints, by maceration and percolation. The dose is 15 to 30 minims for rheumatism, etc. 3637. Tincture Corydalis Compound— Amer. Disp. — Turkey Corn, Yellow Dock, Tag Alder, Figwort. Mandrake, each 1 ounce, diluted Alcohol sufficient to make 22 fl.ounces. Make a Tincture by maceration and perco- lation and dissolve 4 ounces of Sugar in the liquid. Trie dose is from 1 to 4 fl. drachms as an alterative. It is also called Scudders Alterative. 3638. Tincture Curcuma or Turmeric. — Turmeric, in fine powder, 4 ounces, Alcohol sufficient to make a pint. Macerate and percolate. This is. used for coloring alcoholic solutions yellow. 3639. Tincture Elaterium. — Elaterium 8 grains, Alcohol 8 fl.ounces. Triturate the Elaterium first with a small portion of the Alcohol, then add the remainder. The dose is y z to 2 fl. drachms as a hydrogogue cathartic. 3640. Tincture Gentian Ammoniated — Elixir Antiscrofuleux. Fr. — (Paris Codex). — Gentian 1 ounce, Carbonate of Ammonium %. ounce, diluted Alcohol 32 fl.ounces. Make a Tincture. For acid stomach and low spirits. Dose, 1 to 2 fl.drachms. 3641. Tincture Hydrastis Compound — Amer. Disp. — Hydrastis, Lobe- lia Seed, each 2 ounces, diluted Alcohol sufficient to make 1 pint. This is used externally. 3642. Tincture Iodine Decolorized.— This may be made by adding stronger Water of Ammonia 1 part to Tincture of Iodine 5 parts, and then adding a few drops of .Carbolic Acid. See, also, 1766, which is generally preferred. 3643. Tincture Ipecac Compound — Tincture Opium and Ipecac — Liquid Dover 's. — Fluid Extract of Ipecac i}4 fl.ounce, Tincture of Opium sufficient to make 1 pint. Mix and filter. It may also be made with Deodor- ized Tincture of Opium, instead, using the same quantity. A fl. drachm is intended to represent 1 grain Dover "s Powder. 3644. Tincture Lobelia Compound — Antispasmodic Tincture. — Lobe- lia, Sanguinaria, Skunk'Cabbage, Wild Ginger, Pleurisy Root, each X ounce. Alcohol 10 fl.ounces, Water 5 fl.ounces. Make a Tincture by maceration and percolation. Dose, 15 to 150 minims. 3645. Tincture Lobelia and Capsicum Compound — Antispasmodic Tincture — Amer. Disp. — Lobelia, Capsicum, Skunk Cabbage, each 1 ounce TINCTURE — TINCTURES. 951 av., diluted Alcohol sufficient to make i pint. Make a Tincture by macera- tion and percolation. Dose, 30 to 60 minims. 3646. Tincture Myrrh and Capsicum — Hot Drops — No. 6 — Pain Killer. — Capsicum y z ounce, Myrrh 1 ounce, Alcohol 1 pint. Mix, macerate in a warm place for a week or longer, and filter. Other additions are some- times made to this and it is quite generally sold as Pain Killer. The dose is ).\ to 1 ti. drachm in sweetened water. This is also made with }{ ounce of Capsicum in a pint, instead of ' 2 ounce, as above. 3647. Tincture Opium Compound, or Diarrhoea Mixture. — Tincture of Opium, Tincture of Capsicum, Spirit of Camphor, each 3 rl.ounces, purified Chloroform 540 minims, Alcohol sufficient to make 14 fi. ounces. Mix the Chloroform with the Alcohol and add the Tinctures. This is given for diarrhoea in doses of 20 to 60 minims. 3648. Tincture Opium Deodorized with Nitre. — This is prepared in the same manner as Deodorized Tincture of Opium, but instead of Alcohol Spirit of Nitrous Ether is used. It may also be made by evaporating Deo- dorized Tincture of Opium to half its volume and making up to the original volume with Spirit of Nitrous Ether. The strength and dose is the same as ordinary Tincture of Opium Deodorized. 3649. Tincture of Phosphorus Compound.— Phosphorus 4 grains, Abso- lute Alcohol 2>£ rl ounces, Alcohol 1 ounce, Glycerin 2 ll.ounces, Peppermint Essence %, fl.ounce. Shave the Phosphorus and dissolve it in the Absolute Alcohol contained in well-stopped small bottle by the aid of heat of a water- bath. When dissolved add the Alcohol, then the Glycerin and the Essence of Peppermint. Ten minims of this Tincture contain ,,', grain of Phosphorus. 3650. Tincture Rhubarb Compound — Amer. Disp. — Rhubarb 1 ounce. Bitter Root, Hydrastis, Gentian, Prickly Ash Berries, each y 2 ounce, Sas-a- fras, Cardamom, each % ounce, diluted Alcohol sufficient to make 20 rl.ounces. Make a Tincture by maceration and percolation. Dose, : in 4 fl.drachms. 3651. Tincture of Strychnine, Magendie's.— Strychnine 1 -rains, Alco- hol 1 fl.ounce. Dissolve. Care must be used not to dispense this when other preparations of Strychnine are intended. 3652. Warburg's Tincture— (Americanized). Take of Socotrine Aloes 120 grains. Confection Rose, E. I. Rhubarb, Angelica Seed, each 30 grains, Elecampane Root, Saffron, Fennel Seed, Prepared Chalk, each 15 grains, Gentian Root, Zedoary Root, Cubebs, Myrrh, Camphor, each 8 grains, Sul- phate of Quinine 75 grains, dilute, 1 Alcohol enough to make 1 pint. Pow- der the drugs and percolate all except the Confection Rose. Prepared Chalk and Quinine, with the diluted Alcohol until 1 pint is obtained. Rub the Quinine to a tine powder and then with the ( ionfection Rose, triturate this in a mortar with the percolate obtained, and dissolve the Quinine in the mixture by gentle heat; cool, add the prepared chalk, allow to stand 24 hours, and 952 TINCTU R-K — TINCTURES. filter. This has enjoyed a great reputation as a Fever Tincture, being given in doses of about 4 fl. drachms. 3653. Tincture White Pine.— White Pine Turpentine (gum) 2 ounces, Alcohol 14 fl. ounces. Cut the Turpentine into small pieces and dissolve it in the Alcohol by gentle heat of water-bath. This is used for making Syrup of White Pine and Syrup of White Pine Compound, used as cough remedies. 3654. Tincture Zedoary Compound.— Zedoary 4 ounces, Calamus, Gal- angal, each 2 ounces, Chamomile, Aniseed, Caraway, each 1 ounce, Bay Ber- ries, Cloves, each % ounce. Orange Peel, Mace, each l / 2 ounce, Peppermint Water, Alcohol, each 24 fl. ounces. Macerate for two days, then percolate, adding diluted Alcohol sufficient to make 14 fl.ounces, and then add 4 ounces of Chloric Ether. This is employed as a warm carminative Tincture. Dose, 30 to 60 minims. ETHERIAL TINCTURES. 3655. Tincture Asafetida Etherial. — Asafetida, in powder, 1 part, Alco- hol, Ether, each equal quantities, by weight, sufficient to make 5 parts of Tincture. Macerate the gum-resin in the mixed Alcohol and Ether for seven days and then decant. 3656. Tincture Cantharides Etherial.— Cantharides, in powder, 1 part or ounce. Acetic Ether 10 parts or ounces by weight. Macerate for seven days and decant the clear portion. (See also 58.) 3657. Tincture Castor Etherial.— Castor, in powder, 1 part or ounce, Alcohol, Ether, each equal quantities, by weight, sufficient to make 10 parts or ounces of Tincture. Macerate and decant. 3658. Tincture Ergot Etherial. — Ergot, in coarse powder, 1 part or ounce, Ether 3 parts or ounces. Macerate for seven days, pour off, express, and filter. 3659. Tincture Iodine Etherial.— Iodine 80 grains, Ether 3 fl.ounces. Dissolve. 3660. Tincture Iodoform Etherial. — Iodoform 1 part, Ether 4 parts by weight. 3661. Tincture Lobelia Etherial. — Lobelia, in powder, 1 part, Spirit of Ether (2971) 8 parts by weight. Macerate seven days, decant, press, and filter. Dose, 5 to 30 minims. 3662. Tincture Nux Vomica Etherial.— Nux Vomica, in powder, 1 part, Spirit of Ether 10 parts by weight. Macerate seven days, decant, express and filter. Other Etherial Tinctures will be found among the Official Tinctures and under other headings. HOMOEOPATHIC TINCTURES. 953 HOMOEOPATHIC TINCTURES. The Tinctures of Homoeopathic Pharmacy are mostly supplied by Homoeo- pathic manufacturing pharmacists, but there is no reason why they should not be made by pharmacists the same as other Tinctures. As a great number are prepared from a great variety of substances it will be impracticable to give detailed formulas for each, but the general method and formulas for making the different classes and potencies are given. The original Tinctures are called Mother Tinctures ; their dilutions or' attenuations are called Potencies, and are known as first, second, third, etc., in the centesimal scale, or ix, 2\. 3x, etc., in the decimal scale, as explained below. 3663. Class I. Tinctures. Tinctures prepared with equal parts, by weight, of the juice of the plant and Alcohol. The freshly-gathered plant or part which is used is chopped and pounded to a pulp, which is enclosed in a piece of new linen and sub- jected to pressure. The expressed juice is then mixed, with brisk agitation, with an equal weight of Alcohol, the mixture allowed to stand eight days in a well-stopped bottle in a dark, cool place and then filtered. The drug power of Tinctures thus prepared is l / z . Potentiation — Centesimal Scale. — The 1st potency is prepared by mixing 2 minims of the Tincture with 98 minims of diluted Alcohol. The 2d potency is prepared by adding 1 minim of the 1st potency to 99 minims of Alcohol. Each succeeding higher potency is prepared in the same manner as the 2d by adding 1 minim of the next lower to 99 minims of Alcohol. Decimal Scale. — The first or ix potency is prepared by adding 2 minims of the Tincture to 8 minims of diluted Alcohol. The second or 2x potency is prepared by mixing 1 minim of the IX potency with 9 minims of diluted Alcohol. The 3d or 3X potency is prepared by adding 1 minim of the 2x pot< 9 minims of diluted Alcohol, The higher potencies are prepared in a like manner from the next lower. 3664. Class II. Tinctures. Tinctures expressed by the aid of 2 parts of Alcohol added to 3 parts of plant or the part of plant used. The finely-Chopped fresh plant or part which is used is weighed, and in every 3 parts 2 pans by weight, of Alcohol are taken. The chopped plant is moistened with sufficient Alcohol to make it into a thick mass or pulp when well stirred together, The remainder of the Alcohol is then added and the whole mixed together and strained through a piece of new linen. The Tine- 954 HOMOEOPATHIC TINCTURES. ture thus obtained is allowed to stand eight days, then filtered. The drug- power of Tinctures thus prepared is yi. Potentiation. — As the drug power of Tinctures thus prepared is the same as Class I., their potencies are prepared in exactly the same manner as directed for preparing them. 3665. Class III. Tinctures. Tinctures prepared with 2 parts, by weight, of Alcohol to 1 part of plant or part of plant used. The fresh plant or part used is pounded to a fine pulp and weighed, then 2 parts, by weight, of Alcohol are taken ; one sixth of it being first mixed with the pulp and then the remainder added, well stirred together and set aside in a cool, dark place for eight days. The Tincture is then decanted, strained and filtered. The drug power of Tinctures thus prepared is \. Potentiation — Centesimal Scale. — The 1st potency is prepared by mixing 6 minims of the Tincture with 94 minims of diluted Alcohol. The 2d potency is prepared by adding 1 minim of the 1st potency to 99 minims of Alcohol. Each successive higher potency is prepared in the same manner as the 2d, by adding 1 minim of the next lower to 99 minims of Alcohol. Decimal Scale. — The first or ix potency is prepared by adding 6 minims of the Tincture to 4 minims of diluted Alcohol. The second or 2x potency is prepared by adding 1 minim of the ix potency to 9 minims of diluted Alcohol. The 3d or 3.x potency is prepared by adding 1 minim of the 2x potency to 9 minims of diluted Alcohol. The higher potencies are prepared in a like manner from the next lower. 3666. Class IV. Tinctures. Tinctures prepared with 5 parts, by weight, of Alcohol to 1 part of the dried and finely powdered substance, or fresh animal substances. Weigh the substance and pour oVer it 5 parts, by weight, of Alcohol and let the mixture remain eight days or longer, at ordinary temperature, in a dark place, shaking it twice a day, then pour off, strain, and filter. (Fresh animal substances are pounded.) The drug power of Tinctures thus prepared is T ^. Potentiation — Centesimal Scale. — The 1st potency is prepared by adding 10 minims of the Tincture to 90 minims of Alcohol. The 2d potency is pre- pared by adding 1 minim of the 1st potency to 99 minims of Alcohol. Each successive higher potency is prepared in the same manner as the 2d, by add- ing 1 minim of the next lower to 99 minims of Alcohol. Decimal Scale. — As the Tincture contains T V drug power, it corresponds to the first or ix potency. The 2d or 2x potency is prepared by adding 1 minim of the ix potency to 9 minims of Alcohol. The higher potencies are prepared in the same manner from the next lower. HOM(KOPATHIC SOLUTIONS. 955 HOMCEOPATHIC SOLUTIONS. Although these are not properly classified under Tinctures, they most con- veniently come in this connection and are therefore given here. 3667. Class V.— a. Aqueous Solutions. One part, by weight, of the medicinal substance dissolved in 9 parts, by weight, of distilled Water. Amount of drug power of Solution. ,'„. Potentiation — Centesimal Scale. — The 1st potency is made by adding 10 minims of the Solution to 90 minims of distilled Water. The 2d potency is prepared by adding 1 minim of the 1st potency to 99 minims of Alcohol. The higher potencies are prepared in a like manner from the next lower. Decimal Scale. — The original Solution contains -,,,- drug power and is, therefore, the first or ix potency. The second or 2x potency is prepared by adding 1 minim of the Solution to 9 minims of distilled Water. The third or 3X potency is prepared by adding 1 minim of the 2x potency to 9 minims of diluted Alcohol. Higher potencies are prepared from the next lower in the same manner by adding 1 minim to 9 minims of Alcohol. 3668. Class V.— .J. Aqueous Solutions. One part, by weight, of the medicinal substance is dissolved in 99 parts, by weight, of distilled Water. The amount of drug power of the Solution is , ,',,,. Potentiation — Centesimal Scale. — As the drug power of the Solution is T ^ it corresponds to the 1st potency. The 2d potency is prepared by adding 1 minim of the original Solution to 99 minims diluted Alcohol. The higher potencies are prepared from the next lower by adding 1 minim to 99 minims of Alcohol. Decimal Scale. As the Solution contains ,,',„ drug power it corresponds to the second or 2x potency. The third or 3.x potency is prepared by adding 1 minim of the Solution to 9 minims of dilute Alcohol. The fourth or 4X potency is prepared by adding 1 minim of the ;,\ potency to 9 minims of Alcohol. Higher pol prepared in a like manner from the next lower. 3669. Class VI.— a. Alcoholic Solutions. I mi- part, by weight, of the medicinal substance is dissolved in 9 parts, by weight, of Alcohol. The amount of drug power of the Solution is /,,. Potentiation.— I h<- potencies an- prepared in th<- same manner as those of the Aqueous Solutions, <>. using Alcohol as the dilutent. 956 TISANES. TRITURATIONES — TRITURATIONS. 3670. Class VI.— @. Alcoholic Solutions. One part, by weight, of the medicinal substance is dissolved in 99 parts, by weight, of Alcohol. Potentiation. — The potencies are prepared in the same manner as those of the Aqueous Solutions, )3, using Alcohol as the dilutent. For the remaining classes of Homoeopathic preparations, see Triturations. TISANES. In French Pharmacy, Tisanes are slightly medicated infu- sions of some aromatic substance combined with barley, rice, or tamarind water, or other mucilaginous vehicle, the dose being a wineglassful or more every half hour until the medici- nal effect is obtained. They are not used to any extent in this country. TRITURATIONES — TRITURATIONS. Triturations are a class of preparations newly introduced into the Pharmacopoeia, which consist of some active medici- nal agent, reduced by rubbing intimately in a mortar with nine times its weight of Sugar of Milk or some other inert dilutent. But one formula, besides the general formula, for making them is given ; any substance, however, may be made up in the form of a trituration if desired, and, indeed, this is a very good way to exhibit medicines of which a very small dose only is required, as the medicinal agent is finely divided and the dose can be properly regulated. The following is the U. S. P. 1880: 3671. General Formula for Triturations. The Substance, 10 parts. Sugar of Milk, in moderately fine powder, 90 parts. To make 100 parts. Weigh the Substance and Sugar of Milk separately, then place the Substance, previously reduced, if necessary, to a moderately fine powder, in a mortar, add about an equal bulk TRITURATIONES — TRITURATIONS. 957 of Sugar of Milk, mix well by means of a spatula and tritu- rate them thoroughly together. Add fresh portions of the Sugar of Milk, from time to time, until the whole is added, and continue the trituration until the substance is intimately mixed with the Sugar of Milk and finely comminuted. 3672. Trituratio Elaterini. Trituration of Elatcrin. Elaterin, . . . . - 10 parts or grains. Sugar of Milk, in moderately fine powder, 90 parts or grains. To make 100 parts or grains. Mix them thoroughly by trituration. This serves as a sample formula, the only one that is given as officinal in the U. S. P. Others may be made in the same manner. HOMOEOPATHIC TRITURATIONS. In Homoeopathic Pharmacy Triturations are extensively used, but their strength does not at all correspond with those of Regular Pharmacy. Aside from the particular directions for manipulating, which amount only to insure that the substances shall be thoroughly triturated together, the directions for making are as follows : Triturations on the Centesimal Scale. This scale was introduced bj' Hahnemann and is still employed for making the higher potencies, the lower being generally made by the Decimal Scale. 3673. Class VII. Trituration of Dry Medicinal Substances. First Trituration.— Take 1 grain of the medicinal substance and 99 grains or parts of Sugar of Milk, add the medicinal substance to about one third of the Sugar of Milk in an unglazed porcelain mortar and triturate them thoroughly together for six minutes, then scrape the Trituration from tre of the mortar with a porcelain spatula and stir it thor- oughly with the same for four minutes, and again triturate for six minutes as before. To this powder again scraped up for four minutes, now add the sec- ond third of the quantity of Sugar Of Milk, triturate and scrape up as before twice successively, then add the remainder of the Sugar of Milk and combine 958 TRITURATIONES — TRITURATIONS. it with the powder in the mortar by trituration and scraping up as previously directed. This is the first or standard Trituration, containing i per cent, of the medici- nal substance. It is also known as the First Centesimal Trituration. Second Trituration. — Take i grain or part of the first Trituration and 99 grains or parts of Sugar of Milk and prepare by triturating portions of the Sugar of Milk successively, added with the first Trituration in the same man- ner as directed for making the first Trituration. This contains 1 part of the medicinal substance in 10,000, and is called the Second Centesimal Trituration. Third Trituration. — Take 1 grain or part of the second Trituration and 99 grains or parts of Sugar of Milk and prepare a Trituration in the same manner as previously directed. This contains 1 part of the medicinal sub- stance in 1,000,000 parts of the Trituration and is called the Third Centesi- mal Trituration. Liiftiid Potencies. — The third Trituration may be converted into Liquid Potencies by dissolving in Alcohol and Water, in the following manner : One grain or part of the Third Centesimal Trituration is added to 50 minims or parts of distilled Water and agitated, then, when dissolved, 50 minims or parts of Alcohol are added, and the stoppered vial, only two thirds full, is shaken ten times. This is the Fourth Potency. One minim of this liquid (the Fourth Potency) is added to 99 minims of Alcohol and the vial shaken ten times to make the Fifth Potency, and so on, the theory being that the higher the potency used the more effective the medicine. Attenuations above the thirteenth are termed High Potencies. Triturations on the Decimal Scale. This scale was introduced by Dr. Hering, and is used for the lower potencies. First Decimal Trituration. — Take 10 parts or grains of the medicinal substance and 90 parts or grains of Sugar of Milk, and prepare a Trituration in the same manner as is directed for making the Centesimal Trituration. The Second Decimal Trituration is prepared by taking 10 parts of the first with 90 parts of Sugar of Milk. The Third, by taking 10 parts of the second with 90 parts of Sugar of milk, etc., each higher Trituration representing 10 parts of the next below it. Liquid Potencies. — The Sixth Decimal (6x) Trituration is converted into Liquid Potencies by adding 1 grain or part to 50 minims or parts of distilled Water, then, when dissolved, adding 50 minims or parts of Alcohol. This is called the Eighth Potency (8x). One drop of this with 9 of diluted Alco- hol gives the Ninth Potency (9X). Higher potencies in this scale are made in the same manner by adding 1 drop of the next lower to 9 of diluted Alcohol. Do not forget that the mixture must be shaken ten times by ten powerful downward strokes of the arm. TRITURATIONS. TROCHISCI — TROCHES. 959 3674. Class VIII. — Trituration of Liquid Substances. These are prepared according to the Centesimal Scale by triturating 1 minim or part of the liquid with 99 grains or parts of Sugar of Milk for the first, 1 part of the first with 99 of Sugar of Milk for the second, and so on. By the Decimal Scale 1 part of the liquid is triturated with 9 parts of Sugar of Milk for the first, 1 part of the first with 9 parts of Sugar of Milk for the second, and so on. These are converted into Liquid Potencies in the same manner as has already been described. 3675. Class IX.— Trituration of Fresh Vegetable and Animal Substances. Fresh vegetable or animal substances are first pounded or grated to a fine pulp, then triturated and potentized as directed in the foregoing classes. To make the 1st Trituration of the Centesimal Scale 2 parts, by weight, of the substance are triturated with 99 parts, by weight of Sugar of Milk. (Two parts are taken because of loss of weight of the fresh substance by exposure during the trituration.! The 2d Trituration is made with 1 part of the first and 99 parts of Sugar of Milk, as heretofore described. These are converted into Liquid Potencies as before described. Medicated Globules or Pellets. These are prepared by saturating the pellets, globules, or discs with alco- holic solution of whatever potency may be desired, then draining off the superfluous fluid and allowing to dry. These globules or pellets are of different sizes, and are known as No. 8, 10, 15, 20, 25, 30, 40, 50, 60, 70, and 80, according to their size — No. 8 being the smallest, and No. 80 being the largest ; the most commonly used being from No. 20 to No. 40. TROCHISCI -TROCHES. Troches or Lozenges arc flat or slightly convex bodies, made up in various shapes, usually containing some medicinal agent mixed with sugar and gum or <>thcr adhesive substance and intended to dissolve slowly in the mouth and by their solution apply the medicinal agent to the internal surface of the throat and surrounding organs. Like sugar-coated pills, they are now seldom prepared by druggists, manufacturers having mostly monopolized the busi- 960 TROCHISCI — TROCHES. ness and driven the officinal Troches out of use, by introduc- ing more elegant or convenient preparation. Many of the medicinal agents that are introduced in the form of Troches in the Pharmacopoeia formulae seem inappro- priate to be exhibited in this form. It would seem natural that only such remedies should be used in Troches as, by their slow solution, would act locally upon the mucous membrane of the parts with which they come in contact — the throat, larynx, etc. To make Troches, a board about 5x10 inches, with a rim projecting above its surface about % of an inch, and a cylin- drical rolling-pin, should be provided. The ingredients are then to be mixed into' a stiff mass or dough, the board dusted with a mixture of powdered sugar and starch, and the mass rolled out between the projecting lateral edges of the board, filling it entirely from the end out, as far as it will. It is then to be divided with a knife or spatula into the required number of Troches, and dried by gentle heat. Lozenge cutters that make about 12-grains Troches may be obtained of jobbers or dealers in pharmaceutical apparatus, but they cut only a defi- nite size, not adapting themselves to the specific quantity of the medicinal agent directed in the formula. The following formula for Troches represent those now offi- cial in the leading pharmacopoeias. Others can be made as desired in the same general manner. The solid ingredients to Be incorporated are all to be in fine powder. Many of them are called Tablets by manufacturers: 3676. Trochisci Acidi Benzoici. Btnizotc Acid Lozenges. Benzoic Acid 360 grains. Refined Sugar, in powder, 25 ounces av. Gum Acacia, in powder, 1 ounce av. Mucilage of Gum Acacia 2 fl. ounces. Distilled Water, a sufficiency. Mix the Benzoic Acid, Sugar and Gum, add the Mucilage and Water to form a proper mass. Divide into 720 Lozenges and dry in a hot-air chamber at a moderate temperature. Each Lozenge contains half a grain of Benzoic Acid. Br. TROCHISCI — TROCHES. 961 3677. Trochisci Acidi Tannici. Troches of Tannic Acid. Tannic Acid, 100 grains or 6.50 grammes. Sugar, in fine powder, 1000 grains or 65.00 grammes. Tragacanth, in fine powder, ... 25 grains or 1.60 grammes. Orange Flower Water, sufficient to make 100 troches. Rub the powders together until they are thoroughly mixed, then, with Orange Flower Water, form a mass, to be divided into 100 Troches. U. S. The Br. P. makes these only x / 2 grain Tannin in each. 3678. Trochisci Ammonii Chloridi. Troches of Chloride of Ammonium. Chloride of Ammonium, in fine powder, 200 grains or 13.00 grammes. Sugar, in fine powder 1000 grains or 65.00 grammes. Tragacanth, in fine powder 25 grains or 1.60 grammes. Syrup of Tolu, sufficient to make 100 troches. Rub the powders together until they are thoroughly mixed, then, with Syrup of Tolu, form a mass, to be divided into 100 Troches. U. S. 3679. Trochisci Bismuthi. Bismuth Lozc?iges. Subnitrate of Bismuth, 1440 grains. Carbonate of Magnesium, 4 ounces av. Precipitated Carbonate of Calcium 6 ounces av. Refined Sugar, 29 ounces av. Gum Acacia, in powder 1 ounce av. Mucilage of Gum Acacia 2 fl. ounces. Rose Water, a sufficiency. Mix the dry ingredients, then add the Mucilage and form the whole into a proper mass with Rose Water. Divide the mass into 720 Lozenges and dry these in a hot-air chamber at a moderate temperature. Each Lozenge contains 2 grains Subnitrate of Bismuth. Br. 3680. Trochisci Catechu. Troches of Catechu. Catechu, in tine powder 100 grains or 6.50 grammes. Sugar, in fine powder 1000 grains or 65.00 grammes. Tragacanth, in line powder, . . . 25 grains or 1.60 grammes, Orange Flower Water, sufficient to make 100 troches. Rub the powders together until they are thoroughly mixed, then, with < irange Flower Water, form a mass, to be divided into 100 Troches. The I ir. P. directs the same quantity of Catechu. 962 TROCHISCI — TROCHES. 3681. Trochisci Cretae. TrocJies of Chalk. Prepared Chalk, 400 grains or 26.00 grammes. Acacia, in fine powder, 100 grains or 6.50 grammes. Nutmeg, in fine powder 15 grains or 1.00 gramme. Sugar, in fine powder, 600 grains or 39.00 grammes. Rub them together until they are thoroughly mixed, then with Water, form a mass, to be divided into 100 Troches. U. S. 3682. Trochisci Cubebse. Troches of Cubed. Oleoresin of Cubeb 50 grains or 3.25 grammes. Oil of Sassafras, 15 grains or 1. 00 gramme. Extract of Liquorice, in fine powder, 400 grains or 26.00 grammes. Acacia, in fine powder, 200 grains or 13.00 grammes. Syrup of Tolu, sufficient to make 100 Troches. Rub the powders together until they are thoroughly mixed, then add the Oleoresin and Oil and incorporate them with the mixture. Lastly, with Syrup of Tolu, form a mass, to be divided into 100 Troches. U. S. 3683. Trochisci Ferri. Troches of Iron. Hydrated Oxide of Iron, dried at a temperature not exceeding 8o° C. (176 F.), 500 grains or 32.50 grammes. Vanilla, cut in slices 10 grains or 0.65 gramme. Sugar, in fine powder 1500 grains or 97.50 grammes. Mucilage of Tragacanth, sufficient to make 100 troches. Rub the Vanilla first with a portion of the Sugar to a uniform powder, and afterward with the Oxide of Iron and the remainder of the Sugar until they are thoroughly mixed ; then, with Mucilage of Tragacanth, form a mass, to be divided into 100 Troches. U. S. This differs from the U. S. 1870 formula for Troches of Subcarbonate of Iron by the substitution of the Hydrated Oxide of Iron in place of the Sub- carbonate. 3684. Trochisci Ferri Redacti. Reduced Iron Lozenges. Reduced Iron 720 grains. Refined Sugar, in powder 25 ounces av. TROCHISCI — TROCHES. 963 Gum Acacia, in powder, i ounce av. Mucilage of Gum Acacia 2 flounces. Distilled Water, 1 ounce or a sufficiency. Mix the Iron, Sugar, and Gum and add the Mucilage and Water to form a proper mass. Divide into 720 Lozenges and dry them in a hot-air chamber at a moderate temperature. Each Lozenge contains 1 grain of Reduced Iron. Br. 3685. Trochisci Glycyrhizae et Opii. Troches of Liquorice and Opium. Extract of Liquorice, in fine powder, 200 grains or 13.00 grammes. Extract of Opium 5 grains or 0.32 gramme. Acacia, in fine powder, 200 grains or 1 3.00 grammes. Sugar, in fine powder, 300 grains or 19.50 grammes. Oil of Anise 3 grains or 0.20 gramme. Rub the powders together until they are thoroughly mixed, then add the Oil of Anise and incorporate it with the mixture. Lastly, with Water, form a mass, to be divided into 100 Troches. U. S. 3686. Trochisci Ipecacuanhas. Troches of Ipecac. Ipecac, in fine powder, 25 grains or 1.60 grammes. Tragacanth, in fine powder, . . . 25 grains or 1.60 grammes. Sugar, in fine powder, 1000 grains or 65.00 grammes. Syrup of Orange, sufficient to make 100 troches. Rub the powders together until they are thoroughly mixed, then, with Syrup of Orange, form a mass, to be divided into 100 Troches. U. S. The 1870 formula directed about 25 per cent, of Arrow Root ; its place is supplied in the present formula with Sugar. The Br. P. directs the same quantity of Ipecac in each. 3687. Trochisci Krameriae. Troches of Krameria (Rhatany). Extract of Krameria 100 grains or 6.50 grammes. Sugar, in fine powder 1 000 grains or 65.00 grammes. Tragacanth, in fine powder, . . . 25 grains or 1.60 grammes. Orange Flower Water, sufficient to make 100 troches. Rub the powders together until they are thoroughly mixed, then, with Orange Flower Water, form a mass, to be divided into 100 Troches. I'. S. 964 TROCHISCI — TROCHES. 3688. Trochisci Magnesiae. Troches of Magnesia. Magnesia, . " 300 grains or 19.50 grammes. Nutmeg, in fine powder, .... 15 grains or 1.00 gramme. Sugar, in fine powder, 900 grains or 15.50 grammes. Mucilage of Tragacanth, sufficient to make 100 troches. Rub the Magnesia and the pow r ders together until they are thoroughly mixed, then, with Mucilage of Tragacanth, form a mass, to be divided into 100 Troches. U. S. 3689. Trochisci Menthae Piperitae. Troches of Peppermint. Oil of Peppermint 15 grains or 1. 00 gramme. Sugar, in fine powder 1 200 grains or 78.00 grammes. Mucilage of Tragacanth, sufficient to make 100 troches. Rub the Oil of Peppermint and Sugar together until they are thoroughly mixed, then, with Mucilage of Tragacanth, form a mass, to be divided into 100 Troches. U. S. 3690. Trochisci Morphinae. Morphine Lozenges. Hydrochlorate of Morphine 20 grains. Tincture of Tolu, %. fl.ounce. Refined Sugar, in powder, 24 ounces av. Gum Acacia, in powder 1 , ounce av. Mucilage of Gum Acacia, a sufficiency. Distilled Water l / 2 fl.ounce. Dissolve the Morphine in the Water, add this solution to the Tincture of Tolu, previously mixed with 2 fl.ounces of the Mucilage, then add the Gum and Sugar, previously mixed, and more Mucilage, if necessary, to form a proper mass. Divide into 720 Lozenges and dry these in a hot-air chamber at a moderate temperature. Each Lozenge contains ^ grain of the Morphine salt. Br. 3691. Trochisci Morphinae et Ipecacuanhae. Troches of Morphine and Ipecac. Sulphate of Morphine, .... 2^ grains or 0.16 gramme. Ipecac, in fine powder 8 grains or 0.15 gramme. Sugar, in fine powder 1000 grains or 65.00 grammes. Oil of Gaultheria, 1 grain or 0.07 gramme. Mucilage of Tragacanth, sufficient to make 100 troches. TROCHISCI — TROCHES. 965 Rub the powders together until they are thoroughly mixed, then add the Oil of Gaultheria and incorporate it with the mixture. Lastly, with Mucilage of Tragacanth, form a mass, to be divided into ioo Troches. U. S. The Br. formula is about the same. 3692. Trochisci Opii. Opium Lozenges. Extract of Opium 72 grains. Tincture of Tolu yi fl. ounce. Refined Sugar, in powder 16 ounces av. Gum Acacia, in powder 2 ounces av. Extract of Liquorice, 6 ounces av. Distilled Water, a sufficiency. .Make a mass, to be divided into 720 Lozenges. Each Lozenge contains T \ grain Extract of Opium, equal to -V grain of Morphine. 3693. Trochisci Potassii Chloratis. Troches of Chlorate of Potassium. Chlorate of Potassium, in fine powder, 500 grains or 32.50 grammes. Sugar in fine powder 1900 grains or 124.00 grammes. Tragacanth, in fine powder, . . . 120 grains or 6.50 grammes. Spirit of Lemon 10 grains or 0.65 gramme. To make 100 troches. Mix the Sugar with the Tragacanth and the Spirit of Lemon by trituration in a mortar, then transfer the mixture to a sheet of paper and, by means of a bone spatula, mix with it the Chlorate of Potassium, being careful to avoid trituration and pressure to prevent the mixture from igniting or exploding. Lastly, with Water, form a mass, to be divided into 100 Troches. U. S. The Br. P. directs the same quantity of Chlorate of Potassium. 3694. Trochisci Santonini. Santonin Lozenges. Santonin, in powder 720 grains. Refined Sugar, in powder 25 ounces av. Gum Acacia, in powder 1 ounce av. Mucilage of Gum Acacia 2 II. ounces. Distilled Water, a sufficiency. Mix the Santonin, Sugar, and Gum, add the Mucilage and Water to form a proper mass. Divide into 720 Lozenges and dry these in a hot air cham- ber at a moderate temperature. Each Lozenge contains 1 grain of Santonin. Br. The G. P. directs only 0.025 gramme of Santonin in each. 960 TROCHISCI — TROCHES. 3695. Trochisci Sodii Bicarbonatis. Troches of Bicarbonate of Sodium. Bicarbonate of Sodium, .... 300 grains or 19.50 grammes. Sugar, in fine powder, 900 grains or 58.50 grammes. Nutmeg, in fine powder 15 grains or 1 .00 gramme. Mucilage of Tragacanth, sufficient to make 100 troches. Rub the Bicarbonate of Sodium with the powders until they are thoroughly- mixed, then, with Mucilage of Tragacanth, form a mass, to be divided into 100 Troches. U. S. The Br. P. directs 5 grains of Carbonate of Sodium in each. 3696. Trochisci Sodii Santoninatis. Troches of Santoninate of Sodium. Santoninate of Sodium, in fine powder, 100 grains or 6.50 grammes. Sugar, in fine powder 2000 grains or 130.00 grammes. Tragacanth, in fine powder, ... 50 grains or 3.25 grammes. Orange Flower Water, sufficient to make 100 troches. Rub the powders together until they are thoroughly mixed, then, with Orange Flower Water, form a mass, to be divided into 100 Troches. U. S. These Troches are evidently designed to take the place of the Troches of Santonine that were official in the 1870 revision, but it is much to be ques- tioned if Santoniate of Sodium is so effective or safe as the Alkaloid for a vermifuge. 3697. Trochisci Zingiberis. Troches of Ginger. Tincture of Ginger, 200 grains or 13.00 grammes. Tragacanth, in fine powder, ... 50 grains or 3.25 grammes. Sugar, in fine powder 2000 grains or 130.00 grammes. Syrup of Ginger, sufficient to make 100 troches. Mix the Tincture of Ginger with the Sugar and, having exposed the mix- ture to the air until dry, reduce it to a fine powder ; to this add the Traga- canth and mix thoroughly. Lastly, with Syrup of Ginger, form a mass, to be divided into 100 Troches. U. S. A great variety of other Troches or Lozenges may be made in the same general manner as the foregoing. Manufacturers quote long lists of Troches, Lozenges, or Tablets, which are usually compressed, as previously described. Formulas for any desired combination may readily be made by taking the required amount of the medicinal agents to make too Troches, and adding Sugar, Gum, Mucilage, etc., sufficient to make 100 Troches of the required size. TUNGSTEN OR WOLFRAMIUM. UNGUENTA. 967 TUNGSTEN OR WOLFRAMIUM. Symbol, Ti or W. ; Atomic weight, 48. This is an elementary metal discovered by Delhuyart in a heavy metal, found chiefly in Sweden, and called Wolfram. It is a heavy, gray, brittle metal, and may be obtained by reducing Tungstic Acid with charcoal at a white heat. With Oxygen it forms two Oxides, Ti0 3 (Dioxide), and Ti0 3 (Trioxide), which unite with the elements of water, form- ing corresponding acids. It also unites with Chlorine and some elements. Tungstic Acid, H 2 Ti0 4 , combines with Sodium and other alkali bases, forming salts known as Tungstates. 3698. Tungstate of Sodium — Xa„Ti0 4 . — This is used for rendering linen and other fabrics uninflammable by dipping them in a 20 per cent, solu- tion of the salt or painting them with the solution. It is useful for theatrical scenery, etc. It may be prepared by adding 9 parts of finely-powdered Tungsten to 8 parts of fused Carbonate of Sodium and heating them together for some time, then cooling, powdering, and boiling the powder with Water, filtering, and evaporating to dryness. 3699. Tungstic Glue.— This is a compound similar to hard rubber, and used as a substitute for it for many purposes. It is prepared by mixing together a thick solution of Glue with Tungstate of Sodium and adding Hydrochloric Acid. A compound of Tungstic Acid and Glue is precipitated, which, at a temperature of 100 to 104, becomes sufficiently elastic to be moulded or drawn into thin sheets, but is quite solid at ordinary temperature. UNGUENTA — OINTMENTS. Ointments arc fatty preparations of a solid or semi-solid consistence, intended for external application, and usually containing some medicinal substance which is designed to be absorbed or exert its action on tin- parts to which it is applied. The difference between Ointments and Cerates consists chiefly in their consistence- the Ointments as a class being softer tli. m tin- Cerates and being intended, generally, for rubbing in. while the Cerates arc usually spread and applied like a plaster. 968 UNGUENTA — OINTMENTS. The British Pharmacopoeia has done away with this classifi- cation, and now includes all Cerates among the Ointments. As has been previously remarked of Cerates, it seems strange that no attempt was made by the revisers of the 1880 Pharma- copoeia to introduce Petrolatum as a base for Ointments in the place of Lard ; for experience has shown its great superi- ority over it as an Ointment base, and it is now being generally used by pharmacists. It is quite generally directed in the 1885 Br. P. for making Ointments, under the name of Soft Paraffin. White and amber or yellow Petrolatum are now furnished by manufacturers, and it is advisable that druggists should use, in making their Ointments, the color that will best correspond with the color of the Ointments as they have been formerly made — for instance, simple Ointment that has been made with lard and yellow wax, and dark colored Ointments gen- erally, may be made with yellow Petrolatum, while those that have been made with Lard or Benzoinated Lard, if they are white or light colored when finished, should be made with white Petrolatum. Lanoleum or Wool-fat is also recommended and used as an Ointment base, it being more readily absorbed than any other known solid fatty matter. The following are the Ointments official in the leading pharmacopoeias, and also the same made, when practicable, with Petrolatum as a base : 3700. Unguentum. Ointment — Simple Ointment. Lard, 8 parts or 8 ounces. Yellow Wax, 2 parts or 2 ounces. Melt the Wax and add the Lard gradually, then stir the mixture constantly until cool. U. S. 1880. The Br. P., under the title Unguentum Simplex, directs White Wax 2 ounces or 2 parts, Benzoinated Lard 3 ounces or 3 parts, Almond Oil 3 fl. ounces or 3 fl. parts. Melt the Wax and Lard in the Oil on a water-bath, then remove the mixture and stir constantly while it cools. This has the advantage of keeping much better than the U. S. Ointment. UXGUEXTA — OINTMENTS. 3701. Unguentum or Petrolatum Ointment. MADE WITH. PETROLATUM. Petrolatum 8 ounces. Yellow Wax or Paraffin Wax 2 ounces. Melt the Wax and Petrolatum together with gentle heat and stir while cooling. This is now being quite generally used as an Ointment base instead of the official preparation ; it may be used with advantage whenever Ointment is directed or prescribed. It will not become rancid, and is readily incorpo- rated with any substance with which the officinal Ointment is usually used. Ointment or Simple Ointment is the basis of most of the other Ointments. It is very similar to Cerate or Simple Cerate, but contains a less proportion of Wax and is softer, being intended to be absorbed. It is seldom used except in combination. 3702. Unguentum Acidi Borici. Br. Ointment of Boric Acid. Boric Acid, in fine powder, . 2]/ 2 ounces or 1 part. Soft Paraffin (Petrolatum), . p 10 ounces or 4 parts. Hard Paraffin (Paraffin Wax), 5 ounces or 2 parts. Mix the Hard and Soft Paraffin together and add the Boric Acid, distributed over the surface of the liquid by passing it through a sieve, then stir them together constantly until cold. 3703. Unguentum Acidi Carbolici. Ointment of Carbolic Acid— Carbolic Ointment. Carbolic Acid, 1 part or 1 ounce. Ointment, 9 parts or 9 ounces. Mix them thoroughly. This contains 10 per cent, of the Acid. This Ointment is much stronger than manufacturers have been in the habit of furnishing as Carbolized Vaseline, Car- bolized Cosmoline, etc. The)- an- usually made to contain 3 instead of 10 per cent, of Carbolic Acid. 970 UNGUENTA — OINTMENTS. The Br. formula is Carbolic Acid i part, Soft Paraffin (Petro- latum) 12 parts, Hard Paraffin (Paraffin Wax) 6 parts. Melt them and stir constantly until cold. This is more like a Cerate as considered in U. S. Pharmacy than an Ointment. It con- tains about 5 per cent, of the Acid. Carbolic Salve is a popular proprietary preparation. The Carbolic Salves usually contain a larger proportion of Wax than is directed in the foregoing formula. 3704. Unguentum Acidi Gallici. Ointment of Gallic Acid. Gallic Acid, 10 parts or 1 ounce. Benzoinated Lard, .... 90 parts or 9 ounces. Rub the Gallic Acid with the Benzoinated Lard gradually added until they are thoroughly mixed, avoiding the use of an iron spatula. MADE WITH PETROLATUM. Gallic Acid, 1 ounce. Benzoinated Petrolatum, 9 ounces. Rub them together until they are intimately mixed. 3705. Unguentum Acidi Salicylici. Br. Ointment of Salicylic Acid. Salicylic Acid, 1 part. Soft Paraffin (Petrolatum), 18 parts. Hard Paraffin (Paraffin Wax), 9 parts. Melt the Hard and Soft Paraffins together, add the Salicylic Acid and stir until cold. 3706. Unguentum Acidi Tannici. Ointment of Tannic Acid. Tannic Acid, 10 parts or 51 grains. Benzoinated Lard, .... 90 parts or 459 grains. Rub the Tannic Acid with the Benzoinated Lard, gradually added, until they are thoroughly mixed, avoiding the use of an iron spatula. UNGUENTA — OINTMENTS. 971 MADE WITH PETROLATUM. Tannic Acid, i ounce. Benzoinated Petrolatum, 9 ounces. Rub them together until they are thoroughly mixed. 3707. Unguentum Aconitinae. Br. Ointment of Aconitine. This preparation is officinal in the British, but not in the U. S. Pharmacopoeia. The following formula corresponds to the British except that Benzoinated Petrolatum is used instead of Prepared Lard. Aconitine (Aconitia), 8 grains. Alcohol, 30 minims. Benzoinated Petrolatum, 1 ounce av. Dissolve the Aconitine in the Alcohol and mix the solution thoroughly with the Benzoinated Petrolatum. 3708. Uuguentum Antimonii Tartarati. Br. Ointment of Tartr cited Antimony — Tartar Emetic Ointment. Tartrated Antimony, in very fine powder, 100 grains or 1 part. Simple Ointment, 400 grains or 4 parts. Mix thoroughly. The G. P. Unguentum Tartari Stibiati is the same. 3709. Unguentum Aquae Rosas. Ointment of Rose Water — Cold Cream. Expressed Oil of Almond, . 50 parts or 5 ounces av. Spermaceti 10 parts or 1 ounce av. White Wax [o parts or 1 ounce av. Rose Water 30 parts or 3 ounces av. Melt together al a moderate heal the Oil, Spermaceti, and Wax, then gradually add the Rose Water, stirring the mixture briskly and constantly until it is com], and continue the stir- ring until it has become uniformly soft and creamy. U.S. [880. 972 UNGUENTA — OINTMENTS. The G. P. formula for Unguentum Leniens is nearly the same. All druggists who have made Cold Cream know how soon it becomes rancid when exposed. If made with Petrolatum it will remain without change, and a much finer, smoother preparation will result. White Petro- latum should be used for this purpose, but, with the exception of color, the amber Petrolatum will do as well. MADE WITH PETROLATUM. White Petrolatum, 6 ounces av. White Wax, I ounce av. Rose Water, 2)/ 2 fl. ounces. Oil of Rose, 2 minims. Melt the Petrolatum and Wax together by gentle heat, and, when the mixture begins to solidify, gradually incorporate the Rose Water and Oil of Rose with it, by beating briskly until it is cool. 3710. Unguentum Atropinae. Ointment of Atropine. This preparation is officinal in the British, but not in the U. S. Pharmacopoeia. The following formula corresponds to the British except that Benzoinated Petrolatum is used instead of Prepared Lard. Atropia (Atropine), ... 8 grains or 1 part. Alcohol, 30 minims or 3^ fl. parts. Benzoinated Petrolatum, . 1 ounce or 55 parts. Dissolve the Atropine in the Alcohol and mix the solution thoroughly with the Benzoinated Petrolatum. 371 1. Unguentum Belladonnae. Ointment of Belladonna. Alcoholic Extract Belladonna, 10 parts or 51 grains. Diluted Alcohol, 6 parts or 30 minims. Benzoinated Lard, .... 84 parts or 428 grains. Rub the Extract with the diluted Alcohol until uniformly soft, then gradually add the Lard and mix thoroughly. U. S. 1880. UNGUENTA — OINTMENTS. 973 MADE WITH PETROLATUM. Alcoholic Extract of Belladonna, . i ounce av. Diluted Alcohol, y 2 fl. ounce. Benzoinated Petrolatum, .... S}4 ounces av. Rub the Extract with the diluted Alcohol in a warm mortar until uniformly soft and gradually incorporate with it the Petrolatum by rubbing them together. The Br. P. formula is Alcoholic Extract of Belladonna I part, Benzoated Lard 9 parts. Mix them thoroughly. 3712. Unguentum Benzoini. Ointment of Benzoin, U. S. i8jo — Benzoinated Lard, U. S. 1880. Benzoin, in coarse powder, 2 parts or 140 grains. Prepared Lard, .... 100 parts or 16 ounces av. Melt the Prepared Lard by means of a water-bath and, hav- ing loosely tied the Benzoin (in coarse powder) in a piece of coarse muslin, suspend it in the melted Lard, and, stirring them together frequently, continue the heat for two hours, covering the vessel and not allowing the temperature to rise above 6o° C. (140 F.). Lastly, having removed the Benzoin, strain the Lard and stir while cooling. U. S. 1880. Following the alphabetical arrangement of the 1880 Phar- macopoeia this preparation will be found under its new title, Adeps Benzoinatus (see page 76), but, as it belongs properly with the ointments, it is also given here. 3713. Benzoinated Petrolatum. White (or amber) Petrolatum, ... 15 ounces. White (or yellow) Wax, q. s. or . . 1 ounce. Benzoin, in coarse powder, .... ]/^ ounce. Melt the Wax and Petrolatum together, and, having tied the Benzoin loosely in a piece of coarse muslin, suspend it in the melted mixture, stirring them frequently and continuing the heat for two hours at a temperature not exceeding 6o° C. (150 F.i; then remove the Benzoin, strain, and stir while cooling. The amount of Wax used should vary a little to correspond witli the melting point of the Petrolatum, 1 ounce being the 974 UNGUENTA — OINTMENTS. amount required for Petrolatum melting at 120 F., and about one fourth more for that which melts at 104 F. — the object being to have the preparation about the consistence of Lard. The White Petrolatum with White Wax makes a beautiful Ointment, which remains fresh for any length of time. If made with the Amber Petrolatum and Yellow Wax, it is just as good in every way except in color. 3714. Unguentum Calaminae. Br. Ointment of Calamine. Prepared Calamine, . . . . 1 ounce or 1 part. Benzoated Lard, 5 ounces or 5 parts. Mix them thoroughly. 3715. Unguentum Cantharidis. Ointment of Cantliarides. The Br. P. formula is : Cantharides, Yellow Wax, each 1 ounce, Olive Oil 6 fl. ounces. Infuse the Cantharides in the Oil in a covered vessel for 12 hours, then place the vessel in boiling Water for 15 minutes, strain through muslin with strong pressure, add the product to the Wax, previously melted, and stir constantly while the mix- ture cools. The German formula is Cantharides 2 parts, Olive Oil 8 parts, digested for 10 hours on a steam-bath, expressed and fil- tered, and 7 parts of the Oil thus obtained added to 3 parts of Yellow Wax, previously melted, and well stirred while cooling. The U. S. 1870 formula was Cantharides Cerate 120 grains, Resin Cerate 360 grains. Warmed and mixed together. 3716. Unguentum Cereum. G. P. Wax Ointment — Cerasalbe. Olive Oil, 7 parts. Yellow Wax, 3 parts. Melt the Wax and add the Oil. This is similar to Simple Cerate except that Oil is used instead of Lard, making it much softer. UNGUENTA — OINTMENTS. 975 3717. Unguentum Cetacei. Br. Ointment of Spermaceti. This Ointment is officinal in the British Pharmacopoeia, but possesses no advantages over Simple Ointment, and is not so good in any respect as Petrolatum Ointment or Benzoinated Petrolatum. The British formula is as follows : Spermaceti, 5 ounces av. or 10 parts. White Wax, 2 ounces av. or 4 parts. Almond Oil (expressed), 20 fl. ounces or 40 fl. parts. Benzoin, in coarse powder, x / 2 ounce av. or 1 part. Melt together with a gentle heat for two hours, remove the mixture, strain, and stir constantly while it cools. This also may be made with : Petrolatum, 4 ounces. Spermaceti, I ounce. Melt them together and stir while cooling. 3718. Unguentum Chrysarobini. Chrysarobin Ointment . The U. S. P. formula is: Chrysarobin, 10 parts or 60 grains. Benzoinated Lard, .... 90 parts or 540 grains. Rub the Chrysarobin with the Benzoinated Lard, gradually added, until fhey are thoroughly mixed. This is a new officinal, made from " Goa Powder," which has had some reputation in the treatment of skin diseases. It may be made with Benzoinated Petrolatum instead of Lard. It is better made by heating the ingredients together. The Br. P. formula is Chrysarobin 20 grains. Benzoinated Lard 4S0 grains, made in the same manner. 3719. Unguentum Creasoti. Br. Ointment of ( reasote. Creasote, 1 fl. drachm or 1 fl.part. Simple Ointment,. ... 1 ounce a\-. or x parts. Mix them thoroughly. 976 UNGUENTA — OINTMENTS. 3720. Unguentum Diachylon. Diachylon Ointment — Hebra Ointment. The U. S. formula is : Lead Plaster, 60 parts or 6 ounces av. Olive Oil, ... 39 parts or 4 fl. ounces. Oil of Lavender, ... 1 part or 75 minims. Melt together the Lead Plaster and Olive Oil at a moderate heat, then, having permitted the mass to become partly cool, incorporate with it the Oil of Lavender, and stir constantly until cold. Petrolatum may be used in place of the Olive Oil, but the resulting preparation will be of firmer consistence, although this is rather an improvement than otherwise. MADE WITH PETROLATUM. Lead Plaster, 6 ounces av. Petrolatum, 4 ounces av. Oil of Lavender, 75 minims. Melt the Lead Plaster and Petrolatum together at a moder- ate heat, and, when cool enough, add the Oil of Lavender and stir until cold. The G. P. formula is, Lead Plaster 5 parts. Free it from Glycerin by melting and washing it with Water, and, when dry, melt with Olive Oil 5 parts, and stir until cold. 3721. Unguentum Elemi. Br. Ointment of Elemi. Elemi, % ounce or 1 part. Simple Ointment, . . . . 1 ounce or 4 parts. Melt, strain through flannel, and stir constantly until the Ointment solidifies. 3722. Unguentum Eucalypti. Br. Oil of Eucalyptus, by weight, . . . 1 ounce or 1 part. Soft Paraffin (Petrolatum), . | f h Qunces Qr Hard Paraffin (Paraffin Wax, S F Melt the Paraffins together, add the Oil, and stir until cold. UXGUEXTA — OINTMENTS. 977 3723. Unguentum Gallae. Ointment of Nutgall. Nutgall, in No. 80 powder. . 10 parts or 48 grains. Benzoinated Lard, .... 90 parts or 432 grains. Rub the Nutgall with the Benzoinated Lard gradually added, until they are thoroughly mixed. U. S. 1880. The Br. P. formula is Galls, in fine powder, 80 grains, Ben- zoinated Lard I ounce. Mix thoroughly. 3724. Unguentum Gallae cum Opio. Br. Ointment of Nutgall and Opium. This Ointment, though not officinal in the U. S., is much more frequently prescribed than the preceding one. The fol- lowing is the same as the British formula, except that Benzoi- nated Petrolatum is used instead of the Benzoinated Lard : Nutgall, in No. 80 powder 80 grains. Opium, in No. 80 powder, 37 grains. Benzoinated Petrolatum, 1 ounce av. Rub the powders thoroughly with the Benzoinated Petro- latum. It is much used for hemorrhoides and as an astringent. 3725. Unguentum Glycerini. G. P. Glycerin Ointment. This can hardly be called an Ointment as it contains no fatty bodies, but it is used for similar purposes as Ointments. Tragacantli, powdered I part. Alcohol, 5 parts. 1 rl) cerill 50 parts. Rub tin- Alcohol and Tragacanth together, add the GI3 and heat tin- mixture on a steam-bath t<> form a white translu- cent Ointment <»t' uniform consistence. This is quite similar to the Glycerinum Tragacantha (1757) of the Br. I'. 978 UNGUENTA — OINTMENTS. 3726. Unguentum Glycerini Plumbi Sub- acetatis. Br. Ointment of Glycerine of Subacctate of Lead. Glycerine of Subacetate of Lead (1756), 1 part. Soft Paraffin (Petrolatum), 4 parts. Hard Paraffin (Paraffin Wax), . . . . 1^ part. Melt the Paraffins together, add the Glycerine of Subacetate of Lead and stir until the mixture has cooled. 3727. Unguentum Hydrargyri. Mercurial Ointment (Bine Ointment). The U. S. P. 1880 formula is: Mercury 450 parts or 4^ ounces. Lard, 225 parts or 2% ounces. Suet, ' 225 parts or 2^ ounces. Compound Tincture of Benzoin, 40 parts or 3 fl. drachms. Mercurial Ointment (y 2 Mercury), 100 parts or 1 ounce. Mix the Mercury with the Tincture of Benzoin in a mortar, add the Mercurial Ointment and triturate the mixture until globules of Mercury cease to be visible, then add the Lard and Suet, previously melted together and partially cooled, and con- tinue the trituration until globules of Mercury cease to be vis- ible under a magnifying power of ten diameters. MADE WITH PETROLATUM. Mercury, 4 l / 2 ounces. Petrolatum, 3 ounces. Yellow Wax, l% ounce. Compound Tincture of Benzoin, ... 3 fl. drachms. Mercurial Ointment, 1 ounce. Make an Ointment in the same manner as above. The Br. P. formula is Mercury, Prepared Lard, each 1 pound av., Prepared Suet 1 ounce av., rubbed together as above. UNGUENTA — OINTMENTS. 979 The G. P. directs Lard 13 parts, and Mutton Suet 7 parts, to be melted together and, when cold, to be incorporated with Mercury 10 parts. Mercurial Ointment is popularly known as " Unguentum " or "Anguintum." The Ointment, made with one third, instead of one half, Mercury, is generally sold by druggists, but should not be dis- pensed on physicians' prescriptions. This strength may be made by mixing with the 50 per cent. Ointment one half its weight of Petrolatum Ointment. 3728. Unguentum Hydrargyri Ammoniati. Ointment of Ammoniated Mercury {White Precipitate). Ammoniated Mercury, in very fine powder, 10 parts or 52 grains. Benzoinated Lard, .... 90 parts or 468 grains. Rub the Ammoniated Mercury with the Ointment or Ben- zoinated Lard until they are thoroughly mixed. U. S. 1880. The Br. P. formula is the same. MADE WITH PETROLATUM. Ammoniated Mercury, in very fine powder, 1 ounce. Benzoinated Petrolatum, 9 ounces. Rub the Ammoniated Mercury with the Benzoinated Petro- latum until the)* are thoroughly mixed. The G. P. formula, under the title Unguentum Hydrargyri Album, is the same strength. 3729. Unguentum Hydrargyri Compositum. Br. t 'ompound Ointment of Mercury. The British formula uses Yellow Wax and Olive Oil 3 ounces each, instead of the Petrolatum < hutment as here directed. Mercurial < hutment 6 ounces. Petrolatum Ointment 6 ounces. Camphor, in fine powder I|_> ounces. Mell the Petrolatum < hutment, dissolve in it the Camphor, and, when parti)' cool, mix it thoroughly with the Mercurial < )intment. 980 UNGUENTA — OINTMENTS. 3730. Unguentum Hydrargyri Iodidi Rubri. Br. Ointment of Red Iodide of Mercury. Red Iodide of Mercury, in powder, . . 16 grains. Simple Ointment, 1 ounce av. Mix them thoroughly. This was official in the U. S. P. 1870. Petrolatum Ointment may be used instead of Simple Ointment. 3731. Unguentum Hydrargyri Nitratis. Ointment of Nitrate of Mercury {Citrine Ointment). Mercury, 7 parts or \]/ 2 ounce. Nitric Acid, 17 parts or 3^ ounces. Lard Oil, j6 parts or 16^ ounces. Heat the Lard Oil in a glass or porcelain vessel to a temper- ature of 70 C. (158 F.), then add, without stirring, 7 parts or \y 2 ounce of Nitric Acid, and continue the heat so long as a moderate effervescence continues, and allow the mixture to cool. Dissolve the Mercury in the remainder of the Nitric Acid and, with the aid of sufficient heat to prevent the solu- tion from crystallizing, add this solution to the mixture before it has become entirely cold, and mix them thoroughly, avoid- ing the use of an iron spatula. U. S. 1880. There has been considerable discussion regarding the use of Petrolatum in making this Ointment, and the conclusion is that it is not admissible, for the reason that the reaction which is desired between the Nitric Acid and the olein of the Lard Oil, producing elaidin, does not occur with Petrolatum. The Br. P. formula is Mercury, by weight, 4 ounces av., Nitric Acid 12 fl. ounces, Prepared Lard 15 ounces av., Olive Oil 32 fl. ounces. Dissolve the Mercury in the Nitric Acid with the aid of gentle heat, melt the Lard in the Oil by a steam or water-bath in a capacious vessel, and, while the mix- ture is at about 212 F. (ioo° C.) add the Solution of Mercury, also at the same temperature, mixing them thoroughly. Un- less the mixture froths extensively, heat until it does. Then stir until cold. UNGUENTA — OINTMENTS. 981 3732. Unguentum Hydrargyri Nitratis Dilutum. Br. Diluted Ointment of Nitrate of Mercury. Nitrate of Mercury Ointment, Br. (3731), . 1 part. Petrolatum 2 parts. Mix them. 3733- Unguentum Hydrargyri Oxidi Flavi. Ointment of Yellow Oxide of Mercury. Yellow Oxide of Mercury, in very fine powder, . . . .10 parts or 48 grains. Ointment, 90 parts or 432 grains. Rub the Oxide of Mercury with the Ointment, gradually added, until they are thoroughly mixed. U. S. 1880. MADE WITH PETRI ILATUM. Yellow Oxide of Mercury, in very fine powder, 1 ounce. Petrolatum Ointment, 9 ounces. Rub the Oxide of Mercury with the ( )intment, gradually added, until they are thoroughly mixed. 3734. Unguentum Hydrargyri Oxidi Rubri. Ointment of Red Oxide of Mercury — Red Precipitate Ointment. Red Oxide of Mercury (Red Precipitate), in very fine powder, 10 parts or 48 grains. Ointment, 90 parts or 432 grains. Rub the Oxide of Mercury with a small quantity of the ( lintment until a perfectly smooth mixture is obtained, then gradually add the remainder of the ( lintment and mix thor- oughly. U. S. [880. MALI'. \\ II II III Rl 'I VI I M. Red Precipitate, in very fine powder, . . 1 ounce. Petrolatum Ointment 9 ounces. 982 UNGUENTA — OINTMENTS. Rub the Red Precipitate with a small portion of the Oint- ment and then gradually with the remainder until thoroughly mixed. Made with Petrolatum, this Ointment remains perma- nent and unchanged, which is a great advantage over the offi- cinal preparation. The Br. P. Ointment is made with Red Oxide of Mercury 62 grains, Soft Paraffin ^ ounce, Hard Paraffin y^ ounce. Melt the Paraffins and, when cooling, incorporate the Mercury Oxide. The G. P. formula, under the title Unguentum Hydrargyri Rubrum, is Red Oxide of Mercury 1 part, Paraffin Ointment 9 parts. 3735- Unguentum Hydrargyri Subchloridi. Br. Ointment of Subchloride of Mercury. Subchloride of Mercury, 80 grains. Benzoated Lard, 1 ounce av. Mix thoroughly. This is more familiarly known as Calomel Ointment, and is much used as a mild healing absorbent dressing for sores. 3736. Unguentum Iodi. Unguentuni Iodinii. i8jo — Iodine Ointment. Iodine, 4 parts or 20 grains. Iodide of Potassium, . . . 1 part or 5 grains. Water, 2 parts or 10 minims. Benzoinated Lard, .... 93 parts or 475 grains. Rub the Iodine and Iodide of Potassium first with the Water and then with the Lard or Benzoinated Lard, gradually added, until they are thoroughly mixed, avoiding the use of an iron spatula. U. S. 1880. The use of Petrolatum in making this Ointment is not recommended, as with it a greenish-black Ointment results, and the change that occurs is not yet well ascertained. The Br. P. formula is Iodine, Iodide of Potassium, each 32 grains, Glycerin 1 fl. drachm, Prepared Lard 2 ounces av., made in the same manner. UNGUENTA — OINTMENTS. 983 The Compound Iodine Ointment of the U. S. P. 1870 con- tains 15 grains of Iodine, 30 grains Iodide of Potassium, 30 minims Water, 480 grains of Lard. 3737- Unguentum Iodoformi. Iodoform Ointment. Iodoform, in very fine powder, 10 parts or 50 grains. Benzoinated Lard, .... 90 parts or 450 grains. Rub the Iodoform with the Benzoinated Lard, gradually- added, until they are thoroughly mixed. U. S. 1880. The Br. P. formula is the same. MADE WITH PETROLATUM. Iodoform, in very fine powder 1 ounce. Benzoinated Petrolatum, 9 ounces. Rub the Iodoform with a portion of the Benzoinated Petro- latum and then with the remainder, gradually added, until thoroughly mixed. 3738. Unguentum Mezerei. Mczeraim Ointment. Fluid Extract of Mezereum, 25 parts or 1 fl. ounce. Lard, 80 parts or 3^ ounces av. Yellow Wax, 12 parts or |j ounce av. Melt together the Lard and the Wax with a moderate heat. add the Fluid Extract and stir the mixture constantly until the Alcohol has evaporated, then continue to stir until cool. U. S. 1880. MADE WITH PETROLAT1 M. Fluid Extract of Mezereum, . . . i fl.ounce. Petrolatum 3 '-• ounces av. Yellow Wax '-• ounce av. Melt the Petrolatum and Yellow Wax together, add the Fluid Extract and stir the mixture constantly until the Alco- hol has evaporated, then continue to stir until cool. 984 UNGUENTA — OINTMENTS. 3739- Unguentum Paraffini. G. P. Paraffin Ointment — I ^aseline. This is directed to be prepared from : Solid Paraffin (Paraffin Wax), I part. Liquid Paraffin (Paraffin Oil), 4 parts. By melting the Solid Paraffin and incorporating with it the Liquid Paraffin. This is similar to Petrolatum (2447). 3740. Unguentum Picis Liquidae. Tar Ointment. The U. S. P. formula for this Ointment is : ' • each, equal parts. Suet, ) Mix the Tar with the Suet, previously melted with a mod- erate heat, and, having strained the mixture through muslin, stir it constantly until cool. This Ointment is not improved by using Petrolatum, but if it is used, one half as much Yellow Wax as is taken of Petro- latum should be used to give it the proper consistence. The Br. P. formula is Tar 5 ounces, Yellow Wax 2 ounces. The Wax is melted and the Tar added, the mixture being stirred until cool. 3741. Unguentum Plumbi Acetatis. Br. Ointment of Acetate of Lead. This Ointment, though not officinal in the U. S., is fre- quently prescribed. The following is the same as the British, except that Benzoinated Petrolatum is used instead of Ben- zoinated Lard. Acetate of Lead, in very fine powder, 12 grains or 2 parts. Benzoinated Petrolatum, . 1 ounce av. or 73 grains. Mix them thoroughly. The Cerate of Subacetate of Lead is generally preferred. The G. P., under the title Unguentum Plumbi, directs Solu- tion Subacetate of Lead 8 parts, Lard 92 parts, to be mixed together. UNGUENTA — OINTMENTS. 985 3742. Unguentum Plumbi Carbonatis. Ointment of Carbonate of Lead. Carbonate of Lead, in very- fine powder, 10 parts or 48 grains. Benzoinated Lard, .... 90 parts or 432 grains. Rub the Carbonate of Lead (in fine powder) with the Oint- ment or Benzoinated Lard, gradually added, until they are thoroughly mixed. U. S. 1880. MADE WITH PETROLATUM. Carbonate of Lead, in fine powder, . . 1 ounce. Benzoinated Petrolatum, 9 ounces.. Rub the Carbonate of Lead with the Benzoinated Petrola- tum, gradually added, until they are thoroughly mixed. The Br. P. formula is Carbonate of Lead, in fine powder, 62 grains, Simple Ointment 1 ounce av. The G. P. formula, under the title Unguentum Cerussa?, is Car- bonate of Lead 3 parts, Paraffin Ointment (Petrolatum) 7 parts. 3743. Unguentum Cerussae Camphoratum or Camphorated Carbonate of Lead Ointment of the G. P. is made by rubbing Camphor, in powder, 5 parts, with Carbonate of Lead Oint- ment 95 parts. 3744. Unguentum Plumbi Iodidi. Ointment of Iodide of Lead. Iodide of Lead, 10 parts or 4.X grains. Benzoinated Lard, .... 90 parts or 432 grains. Rub the Iodide "I" Lead (in fine powder) with the Ointment or Benzoinated Lard, gradually added, until they are thor- oughly mixed. U.S. 1SS0. MADE w nil PETRI »LATU \i. [odide of Lead, in very fine powder, . . i ounce. Benzoinated Petrolatum 9 oun Kul) the Iodide of Lead with the Benzoinated Petrolatum, gradually added, until they are thoroughly mixed. The Br. P. formula is Iodide of Lead 62 grains, Simple Ointment 1 ounce av. Mix thorough!}'. 986 UNGUENTA — OINTMENTS. 3745. Unguentum Plumbi Tannici. Ointment of Tannatc of Lead. Tannic Acid I part. Solution Subacetate of Lead, 2 parts. Lard, 17 parts. Rub the Acid with the Solution of Lead to a smooth paste, then incorporate with the Lard. It should be freshly- prepared. 3746. Unguentum Potassae Sulphuratae. Br. Ointment of SnlpJiurated Potash. Sulphurated Potash, ... 30 grains or 5 parts. Hard Paraffin (Paraffin Wax), % ounce or 18 parts. Soft Paraffin (Petrolatum), . 3^ ounce or 55 parts. Triturate the Sulphurated Potash in a glass or porcelain mortar and gradually add the melted Paraffins, rubbing them together until the Ointment is perfectly smooth and free from grittiness. This should be freshly prepared when wanted for use. 3747. Unguentum Potassii Iodidi. Ointment of Iodide of Potassium. Iodide of Potassium, ... 12 parts or 61 grains. Hyposulphite of Sodium, . 1 part or 5 grains. Boiling Water, 6 parts or 30 minims. Benzoinated Lard, . . . . 81 parts or 413 grains. Dissolve the Iodide of Potassium and the Hyposulphite of Sodium in the boiling Water in a warm mortar, then gradually add the Benzoinated Lard and mix thoroughly. U. S. 1880. The Hyposulphite of Sodium is added to prevent the dis- coloration which formerly occurred in this Ointment after standing. . MADE WITH PETROLATUM. Iodide of Potassium, in fine powder, . . 60 grains. Hyposulphite of Sodium, in fine powder, 5 grains. Boiling Water, 30 minims. Benzoinated Petrolatum, 413 grains. UNGUENTA — OINTMENTS. 987 Dissolve the Iodide of Potassium and the Hyposulphite of Sodium with the boiling Water in a warm mortar, gradually add the Benzoinated Petrolatum and mix thoroughly. The Br. P. formula is nearly the same as the U. S. The G. P. formula, under the name Unguentum Kalii Jodati, is Iodide of Potassium 20 parts, Water 10 parts, Paraffin Oint- ment (Petrolatum) 170 parts. 3748. Unguentum Resinae. Ointment of Resin — Basilicon Ointment. The Br. P. formula is : Resin, in coarse powder, 8 ounces av. Yellow Wax. 4 ounces av. Simple Ointment, 16 ounces av. Almond Oil, 2 fl. ounces. Melt at a low temperature, strain the mixture while hot through flannel and stir constantly while it cools. The G. P. formula is common Olive Oil 45 parts, Yellow Wax, Resin, Mutton Suet, each 15 parts, common Turpentine (gum) 10 parts. Melt them together, strain, etc. This is sim- ilar to the U. S. Compound Resin Cerate. The U. S. Resin Cerate is similar, but a firmer preparation than either of the others. (See page 221.) 3749. Unguentum Rosmarini Compositum. G. P. Rosemary Ointment — Xervensctlbe. Lard 16 parts, Mutton Suet 8 parts, Yellow Wax 2 parts, expressed Oil of Nutmeg 2 parts. Mix them together and add to the finished Ointment, Oil of Rosemary 1 part, Oil of Juniper Berries I part. 3750. Unguentum Sabinae. Sa;' in Ointment. The Br. P. directs this to be prepared from fresh Savin Tops 8 ounces. Yellow Wax x ounces, Benzoated Lard n> ounces, by melting the Laid and Wax together on a water-bath and 988 UNGUENTA — OINTMENTS. digesting for 24 hours with the Savin, then removing the heat and expressing the Ointment through calico. The G. P. directs Extract of Savin 1 part, with Wax Oint- ment 9 parts, melted together and mixed while cooling to form an Ointment. The U. S. Cerate of Savine is made from the Fluid Extract and corresponds nearly with the foregoing. (See page 222.) 3751. Unguentum Staphisagriae. Br. Ointment of Staphesacre. Staphesacre Seeds, 4 ounces or 1 part. Benzoated Lard, 8 ounces or 2 parts. Crush the Seeds and macerate them in the Lard, kept melted over a water-bath for two hours, strain through calico and set aside to cool. This contains about 10 per cent, of Oil obtained from the Seed. 3752. Unguentum Stramonii. Stramonium Ointment. Extract of Stramonium, . . 10 parts or 51 grains. Water, 5 parts or 25 minims. Benzoinated Lard, .... 85 parts or 433 grains. Rub the Extract with the Water until uniformly soft, then gradually add the Lard or Benzoinated Lard, and mix them thoroughly. U. S. 1880. This may be made with Benzoinated Petrolatum instead of Lard. 3753- Unguentum Sulphuris. Snlpliw Ointment. Sublimed Sulphur, .... 30 parts or 144 grains. Benzoinated Lard, .... 70 parts or 336 grains. Rub the Sulphur with the Lard or Benzoinated Lard, grad- ually added, until they are thoroughly mixed. U. S. 1880, Precipitated or Lac Sulphur makes a much smoother Oint- ment, and is much to be preferred. UNGUENTA — OINTMENTS. 989 MADE WITH PETROLATUM. Sublimed Sulphur, 3 ounces. Petrolatum, -J ounces. Mix them thoroughly by rubbing them together. The Br. P. formula is Sublimed Sulphur 1 ounce mixed with Benzoated Lard 4 ounces. 3754. Unguentum Sulphuris Alkalinum. Alkaline Sulphur Ointment. Washed Sulphur, 96 grains. Carbonate of Potassium, 48 grains. Water, 24 minims. Benzoinated Lard, 312 grains. Rub the Sulphur with the Carbonate of Potassium and the Water, gradually add the Benzoinated Lard and mix thor- oughly. U. S. 1880. This may be made with Benzoinated Petrolatum instead of Benzoinated Lard. 3755- Unguentum Sulphuris Iodidi. Br. Ointment of Iodide of Sulphur. Iodide of Sulphur, ... 30 grains or 5 parts. Hard Paraffin, ^ ounce or 18 parts. Soft Paraffin, ^ ounce or 55 parts. Triturate the Iodide of Sulphur in a glass or porcelain mor- tar and gradually add the melted mixture of Paraffins, rubbing them together until cold. 3756. Unguentum Tabaci. (hutment of Tobaeco. Tobacco, in fun- powder y> ounce. Lard S ounces. Water, ,1 sufficient quantity. Moisten the Tobacco with a little Water, introduce it into a conical glass percolator, and, having pressed it firmly, pour 990 UNGUENTA — OINTMENTS. Water upon it until 4 fl. ounces of liquid have passed. Evap- orate this liquid to the consistence of a soft extract, and mix it thoroughly with the Lard. U. S. 1870. This may be made with Petrolatum instead of Lard. 3757- Unguentum Terebinthinae. Turpentine Ointment. The Br. P. formula is Oil of Turpentine 1 fl. ounce, Resin, in coarse powder, 54 grains, Yellow Wax y 2 ounce av., Prepared Lard y 2 ounce av. Melt the solid ingredients together and, while cooling, add the Oil and stir. The G. P. formula is Common Turpentine (gum), Yellow Wax, Oil of Turpentine, each equal parts by weight. This is used as a stimulating Ointment for sores, ulcers, etc. The Br. preparation has less consistence than the German, and may be used when a very soft Ointment is desired, but the German is generally preferred. 3758. Unguentum Veratrinae. Veratrine Ointment. Veratrine, 4 parts or 20 grains. Alcohol 6 parts or 35 minims. Benzoinated Lard, .... 96 parts or 480 grains. Rub the Veratrine with the Alcohol in a warm mortar until dissolved, then gradually add the Benzoinated Lard and mix thoroughly. U. S. 1880. MADE WITH PETROLATUM. Veratrine, 20 grains. Alcohol, 35 minims. Benzoinated Petrolatum, 480 grains. Rub the Veratrine with the Alcohol in a warm mortar until dissolved, then gradually add the Benzoinated Petrolatum and mix thoroughly. The Br. P. formula is Veratrine 8 grains, Hard Paraffin (Par- affin Wax) y ounce av., Soft Paraffin (Petrolatum) ^ ounce av., Olive Oil 1 fl. drachm. Rub the Veratrine and Oil together and incorporate with the melted Paraffins. UN GUEXTA — OINTMENTS. 991 3759- Unguentum Zinci Oxidi. Oxide of Zinc Ointment. Oxide of Zinc, 20 parts or 96 grains. Benzoinated Lard, .... 80 parts or 384 grains. Rub the Oxide of Zinc with an equal weight of Benzoinated Lard, previously melted, until the mixture is perfectly smooth, then add the remainder of the Benzoinated Lard and mix thoroughly. U. S. 1880 MADE WITH PETROLATUM. Oxide of Zinc, 2 ounces. Benzoinated Petrolatum, 8 ounces. Rub the Oxide of Zinc with an equal weight of Benzoinated Petrolatum in a warm mortar until they are thoroughly and smoothly mixed, then add the remainder of the Benzoinated Petrolatum and mix them thoroughly. The Br. P. Ointment of Zinc is Oxide of Zinc 80 grains, Ben- zoinated Lard I ounce av., mixed in the same manner as above directed. The G. P. formula is common Oxide of Zinc 1 part. Lard 9 parts. 3760. Unguentum Zinci Oleati. Br. Ointment of Oleate of Zinc. < )leate of Zinc, i ounce or 1 part. Soft Paraffin (Petrolatum), . . . 1 ounce or 1 part. Mix by the aid of a little heat and stir until nearly cold. Unofficial Ointments. The foregoing ollicial Ointments include the greater share that are used to any extent in dispensing pharmacy, but many others are or have been used and are now occasionally called for. It would be impracticable to give detailed formulas for all of them, as the list of official Ointments is already sufficient for the general uses of pharmacy and medicine, so only the more important ones, for which there is sonic demand, are mentioned and classi- owing their composition. They can be made in the same general way as is directed for similar official I ointments. Solid drugs generally should be reduced to fine powder. Alkaloids should be rubbed with a few drops of Alcohol. Extracts should be slightly softened with Alcohol or Water. I oint- ment made with I.ard or with Petrolatum may be used as a base, the latter 992 UNGUENTA — OINTMENTS. being generally preferable. Lard or Petrolatum alone are sometimes used when softer Ointments are desired. The following list shows the composition of the more important Unofficial Ointments: SIMPLE UNOFFICIAL OINTMENTS. No. Ointment of Composed of 3761 Alum 3762 Ammonium Carb 3763 Arsenical (Mild) ... . 3764 Arsenical (Hospital) 3765 Arsenical (Cancer) 3766 Arseniate of Iron 3767 Arseniate of Sodium. . . 376S 1 Balsam Peru 3769 Balsams, other 3770 Bromide Salts 3771 Bromine 3772 Brown (Ungt. Fuscum). 3773 Cadmium Salts 3774 Caffeine 3775 Camphor 3776 Cantharidine 3777JCapsicum 3778 1 Catechu 3779 Chalk 3780 Chamomile 3781 Charcoal 3782 Cherry Laurel 3783 Chloral Hydrate 3784 Chloride of Lead 3785 Chlorine 3786 Chloroform 3787 Cocculus Indicus 3788 Cod Liver Oil 3789 Colocynth 3790 Corrosiye Sublimate . . . 379iCroton Oil 3792 Cyanide of Mercury ... 3793 Cyanide of Potassium . 3794 Elder Flower 3795 Elder Leaf, green 3796 Emetina 3797 Euphorbium 3798 Foxglove 3799 Garlic 3800 Gold (Pomade d'Or)... 3801 Gold Chloride 3802 Hellebore 3803 1 Hemlock (Conium) 3804 Hops 3805 1 Iodide of Sulphur 3806 Laurel 3S07 Lupuline 3808 Naphthalin 3809 Picrotoxin 3810 Pitch (Black Basilicon) . 3811! Poplar Buds 3842 Quinine 3S13 Scrof ularia 3814 Squill 3815 Strychnine 3816 Sulphate of Zinc 3X17 Virdigris 3818 W 1 Soot Alum 40 grains, Ointment 1 ounce. Carbonate Ammonium 1 drachm, Ointment 9 drachms. Arsenic 3 grains, Ointment 1 ounce. Arsenic 15 grains, Ointment 1 ounce. Ar.-i'iiic 40 grains, Ointment 1 ounce. Arseniate of Iron 20 grains, Ointment 1 ounce. Arseniate of Sodium 30 grains, Ointment 1 ounce. Balsam Peru 1 drachm, Ointment 1 ounce. The required Balsam 1 drachm, Ointment 1 ounce. The Bromide Salt 30 grains, Ointment 1 ounce. Bromide Potassium 20 grs., Bromine 10 m., Ointment 1 oz. Nitric Oxide of Mercury 30 grains, Resin Ointment 1 oz. J The Cadmium Salt 1 drachm, Ointment 1 ounce. Caffeine 5 grains, Ointment 1 ounce. Camphor 1 to 2 drachms, Ointment 1 ounce. Cantharidine 1 grain, Ointment 1 ounce. Oleo-resin Capsicum 5 grains, Ointment 1 ounce. Catechu 30 grains, Ointment 1 ounce. Prepared Chalk % ounce, Petrolatum 1 ounce. Chamomile Extract 1 drachm, Ointment 1 ounce. |Charcoal 1 part, Resin Ointment 3 parts. Cherry Laurel Oil 1 drachm, Ointment 9 drachms. Chloral Hydrate 1 drachm, Ointment 9 drachms. Chloride of Lead 1 drachm, Ointment 9 drachms. Chlorine Water 1 part, Lard 9 parts. Chloroform 1 drachm, Ointment 9 drachms. Cocculus Indicus 2 drachms, Lard 8 drachms. Cod Liver Oil 7 parts, White Wax and Cetaceum each 1 pt. Colocynth Pulp 1 part, Lard 8 parts. Corrosive Sublimate 5 grains, Spermaceti Oint. 1 ounce. Croton Oil 20 minims, Lard 1 ounce. Mercury Cyanide 10 grains, Lard 1 ounce. ! Cyanide of Potassium 5 grains, Cold Cream 1 ounce. Elder Flowers and Lard, equal parts, boiled together. Elder Leaves 3 pts., Lard 3pts., Suet3pts., boiled together. Emetina 30 grains, Alcohol q. s., Lard 1 ounce. Euphorbium 30 grains, Lard 1 ounce. Digitalis, fresh leaves, Lard, each equal pts., boiled together. Garlic, fresh bruised 2 pts., Lard 3 pts., simmered together. Gold Leaf 12 grains, rubbed with Ointment 1 ounce. Chloride of Gold 12 grains, Ointment 1 ounce. White Hellebore 2 drachms, Petrolatum 1 ounce. Conium Extract 1 drachm, Ointment 9 drachms. Hops, fresh, 1 part, Lard 5 parts, simmered together. Sulphur Iodide 30 grains, Petrolatum 1 ounce. Laurel Oil, expressed, 2 ozs., Suet 1 oz., Oil Turp. ij^ dr. Lupulin 1 part, Lard 3 parts, digest by heat. Naphthalin J£ ounce, Petrolatum 8 ounces. Picrotoxin 10 grains, Petrolatum 1 ounce. Pitch, Resin, Beeswax, each 1 ounce, Olive Oil 2 ounces. Poplar Buds, fresh, 1 part, Lard 4 parts, digest with heat. Sulphate of Quinine 2 drachms, Lard 6 drachms. Figwort Leaves, fresh, Lard, each 2 parts, Suet 1 pt., boil. Squill, in fine powder, 1 part, Mercurial Ointment 2 parts. Strychnine 16 grains, Lard or Petrolatum 1 ounce. Sulphate of Zinc, fine powder, 1 drachm, Lard 1 ounce. Verdigris 30 grains, Resin Ointment 1 ounce. Wood S iot and Lard, mixed, equal parts. UN< .UEXTA — OINTMENTS. 993 Compound Unofficial Ointments. Of the great number of Compound Ointments that are known but few, except those official in the leading pharmacopoeias (and already given), are of sufficient interest to require notice. Others will be found among The Stand- ard Remedies. 3820. Alkaline Ointment. — Carbonate of Sodium (^Sal Soda) 1 drachm, fresh slacked Lime 30 grains, powdered Opium 1 grain, Lard or Petrolatum 1 ounce. Mix them. 3821. Antiperiodic Ointment. Br. — Sulphate of Ouinine 90 grains, Saccharated Carbonate of Iron 60 grains, Oil Cajuput 30 drops, Petrolatum or fresh Butter 1 ounce. Mix them. 3822. Aromatic Ointment. — Yellow Wax, Oil of Laurel, expressed, each 1 ounce, Simple Ointment 13 ounces. Melt them together and add, when nearly cool, Oil of Juniper, Peppermint, Lavender, and Rosemary, each 40 minims. 3823. Astringent Ointment.— The official Ointment of Galls and the Lead Ointments are often used as Astringent Ointments. The following is also used : Powdered Catechu 90 grains, softened with boiling Water 2 drachms, and mixed with Spermaceti Ointment or Simple Ointment, melted until it forms a mass. Or, from Alum 1 ounce, Catechu 3 ounces, both in very fine powder, added to Olive Oil 10 ounces, in which Yellow Resin 4 ounces is melted, and stirred until cool. 3824. Egg Ointment. — Oil of Almonds i l / 2 ounce, Beeswax x / 2 ounce. Melt them together and, when cool but still fluid, add the Yolk of 1 Egg and 30 drops of Balsam of Peru and beat them thoroughly together. 3825. Egyptian Ointment. — Burnt Alum 1 part, Verdigris 10 parts, strong Vinegar 14 parts, purified, thick Honey 32 parts. Mix them well together. 3826. Juniper Tar Ointment. — Lard and Suet, each 6 parts, Beeswax 4 part-. Melt them together and, while cooling, add Oil of Juniper Tar (Oil of Cade) 16 parts, Oil of Lavender 1 part. 3827. Labdanum Ointment.— Labdanum 6 drachms, Petrolatum 2 ounces, Oil of Mace 1 drachm, Oil of Wormwood 10 drops, Balsam Peru 2 drachms. Make an Ointment. 3828. Mayer's Ointment — Compound Lead Ointment Amer. Disp. olive Oil 2ji pounds, White Pine Turpentine '2 pound. Beeswax, unsalted Butter, each 4 ounces, Red Lead 1 pound, Money u ounces, powdered 1 am- Melt the Oil, Turpentine, Beeswax, and Butter together and strain, then heat to nearly boiling and gradually add the Red Lead, stirring the mixture constantly until it becomes brown or black, then remove from the tire and. u hen it becomes somewhat cool, add 10 h the l loney and I !am- phor, previously mixed together. 994 UNGUENTA. URANIUM. UREA. 3829. Ointment Nervine — Nervine Balsam.— Expressed Oil of Mace, Ox Marrow, each 4 ounces. Melt by gentle heat and add Oil of Rosemary 2 drachms, Oil of Cloves 1 drachm, Camphor 1 drachm, Balsam Tolu 2 drachms (the last two dissolved in Alcohol 4 drachms). 3830. Pomade pour le Toncher or Obstetrical Ointment. — Yellow Wax, Spermaceti, each 1 ounce, Olive Oil 16 ounces. Melt together, strain, add Solution of Caustic Soda 1 fl. ounce, and stir until nearly cold. 3831. Stramonium Ointment Compound — {Beach's). — Bittersweet, bark of root, Stramonium Leaves, Cicuta Leaves, Deadly Nightshade, Yellow Dock Root, each 2 ounces, Lard 1 pound, Venice Turpentine 2 ounces. Bruise the roots and leaves, cover them with Alcohol and digest with a moderate heat for four hours, then add the Lard and continue the heat until the leaves are crisped. Lastly, strain and express through linen, add the Turpentine and stir constantly until cold. URANIUM. Symbol, U ; Atomic weight, 238.5. This is a rare metal, discovered by Klaproth about a cen- tury ago, but seldom used. It is distinguished as having the greatest combining weight of any known element. • It unites with Oxygen, forming Uranic Oxide, U 2 3 , and with Chlo- rine, forming two Chlorides, U 2 C1 S and UC1 2 . Its salts are used in photography, but are seldom employed in pharmacy. UREA. COH 4 U 2 . This is a constituent of urine, and is noted as being the first organic compound artificially produced. Artificial Urea is employed in medicine. Its salts are sometimes employed as diuretics. 3832. Nitrate of Urea. — This may be prepared by saturating artificial Urea with Nitric Acid, concentrating and crystallizing. The dose is from 2 to 5 grains as a diuretic, especially in dropsy. Other salts of Urea may be prepared in the same manner. 3833. Uric Acid — Lit hie Acid. — This occurs in the urine of certain animals and in morbid conditions of the kidneys. It is supposed to be the principal cause of acute rheumatic affections, gout, etc.. and is one of the most common constituents of urinary calculi. VANADIUM. VANILLIN. VAPORES — VAPORS. 995 VANADIUM. Symbol, V; Atomic weight, 51.3. A rare metallic element, discovered in certain iron and cop- per ores in various parts of the world. The salts of Vana- dium are chiefly used in dyeing, but as it is very expensive it is only used by experienced dyers. Vanadium black is the rich- est and most permanent black dye known. An ink is also made with Vanadium Ammoniate, Acid, and infusion of Galls, which is very permanent and durable. With Oxygen it forms several oxides, but the most important salts of Vanadium are its ammonia compounds, known as Vanadinate of Ammonium. 3834. VANILLIN. C 8 H 8 3 . Vanillin is the odorous crystalline principle of Vanilla and is chemically the Aldehyd of Methyl-protocatechuic Acid. It is also artificially prepared from the sap-wood or juice of pine trees, and from many other substances, by complex processes. It has been prepared and considerably sold for making Extract of Vanilla, but the flavor of the product lacks the richness and delicacy of the true extract or tincture made from Vanilla. One ounce of Vanillin with 1^ gallon of Cologne Spirit, 1 V\ gallon of Water, and ^ gallon of Syrup, colored with Caramel, produces a fair imitation of Vanilla Extract. VAPORES VAPORS. In British Pharmacy Vapors are solutions of medicinal sub- stances which ait- volatilized by passing through a suitable apparatus, and an- intended to be us.-d by inhalation. It seems hardly necessary to have made them official. For the inhalation of different substances different kinds of apparatus are required. 996 VAPO RES — VAPORS. 3835. Vapor Acidi Hydrocyanici — Inhalation of Hydrocyanic Acid. — Diluted Hydrocyanic Acid 10 to 15 minims, Water (cold) 1 fl.drachm. Mix in a suitable apparatus and let the vapor that arises be inhaled. 3836. Vapor Chlori — Inhalation of Chlorine.— Chlorinated Lime 2 ounces, Water (cold) a sufficiency. Put the powder into a suitable appara- tus, moisten it with the Water and let the vapor that arises be inhaled. 3837. Vapor Coninae — Inhalation of Conine. — ■ Juice of Hemlock (Co- nium) y z fl. ounce, Solution of Potash 1 fl. drachm, distilled Water 1 fl. ounce. Put 20 minims of the mixture on a sponge in a suitable apparatus so that the vapor of hot water passing over it may be inhaled. 3838. Vapor Creasoti — Inhalation of Creasote. — Creasote 12 minims, boiling Water 8 fl.ounces. Mix the Creasote and Water in an apparatus so arranged that air may be made to pass through the solution and may after- ward be inhaled. 3839. Vapor Iodi — Inhalation of Iodine. — Tincture of Iodine 1 fl.drachm, Water 1 fl.ounce. Mix in a suitable apparatus, which can be gently heated, and let the vapor that arises be inhaled. 3840. Vapor Olei Pini Sylvestris — Inhalation of Fir-wool Oil. — Oil of Fir-wool 40 minims, Light Carbonate of Magnesium 20 grains, Water a sufficiency. Rub the Oil with the Magnesium and gradually add sufficient Water to produce 1 fl.ounce. Put 1 fl.drachm of the mixture with 10 fl.ounces of cold Water and 10 fl.ounces of boiling Water into an apparatus so arranged that air may be made to pass through the solution and may after- ward be inhaled. Other Vapors. A great variety of other volatile substances may be employed in the form of vapor in a similar manner. 3841. Vapor of Carbolic Acid is prepared in the same manner as Vapor of Creasote. 3842. Vapor of Nitrite of Amyl is prepared with Nitrite of Amyl 8 min- ims in Alcohol 1 ounce, and a fl.drachm used in a pint of Water at ioo° F., for asthma, headache, etc. 3843. Vapors of Menthol, Thymol, and other similar substances are prepared in the same manner as Vapor of Fir-wool Oil. 3844. Vapor of Terebene and of Essential Oils, etc., are prepared in the same manner. Besides this method of applying Vapors, Steam Atomisers are considera- bly used for the local treatment of the nasal organs and throat. By this means a spray of the medicinal substance is applied directly to the parts. Inhalations of Oxygen and other gaseous substances in the form of vapor or otherwise are also employed, with suitable apparatus. VINA — WINES. 997 VINA — WINES. As considered in Pharmacy, Wines are liquid medicinal prep- arations in which Wine is chiefly used as the menstruum or vehicle for holding the medicinal principles in solution. They are similar to, but generally weaker than, Tinctures. The basis of the Medicinal Wines is the fermented juice of different varieties of grapes — the light colored varieties being known in U. S. Pharmacy as Vinum Album or White Wine, and the dark varieties being known as Vinum Rubrum or Red Wine. In other pharmacopoeias specific varieties of Wines are directed, as Vinum Xertcunt, Sherry Wine, Vinum Oporto or Port Wine, etc. As found in the market, Wines possess scarcely sufficient alcoholic strength for the solution and preservation of most medicinal substances. The U. S. Pharmacopoeia therefore directs that they shall be fortified with Alcohol sufficient to make up for this deficiency, as instanced in Vinum Album Fortius. The following are the official Wines of the leading phar- macopoeias : 3846. Vinum Album. This is described in the U. S. P. as a p. lie amber-colored or straw-colored alcoholic liquid, made by fermenting the unmodified juice of the grape, freed from seeds, stems, and skins. It should not contain less than 10 nor more than [2 per cent., by weight, of Absolute Alcohol. 3847. Vinum Album Fortius. Stronger White Wine. White Wine 7 parts or 55 fl. ounces. Alcohol I part or . , « _. ll. ounces. Mix tin-in. When tested for Alcohol, as described under White Wine, Stronger White- Wine should contain not less than 20 per cent, nor more than 25 per cent, oi Absolute Alco- hol, by weight. V . S. t88o. 998 VINA — WINES. The object of adding Alcohol is to have a Wine for pharma- ceutical purposes that will contain a definite and sufficient quantity of Alcohol to dissolve and preserve medicinal agents with which it is combined. This preparation is used as the base of all the medicinal Wines of the U. S. 1880 Pharmaco- poeia, in place of " Sherry Wine," which was directed in all the formulas of the 1870 revision. While this change is no doubt beneficial in a general sense, the present preparations will not necessarily correspond in flavor nor appearance with those that have been formerly prepared for any Wine, except a Red Wine may be used. 3848. Vinum Aloes. Wine of Aloes. Purified Aloes, 6 parts or 1 ounce av. Cardamom, 1 part or 73 grains. Ginger, 1 part or y^ grains. Stronger White Wine, sufficient to make a pint. Mix the Aloes, Cardamom, and Ginger and reduce them to a moderately coarse powder, macerate the powder with 13 ounces of the Wine for seven days, with occasional agitation, and filter through paper, adding through the filter enough Wine to make a pint of the finished liquid. U. S. 1880. The Br. formula is Socotrine Aloes 1 % ounce av., Cardamom Seeds, bruised, 80 grains, Ginger, in coarse powder, 80 grains, Sherry 40 fl. ounces. Macerate for seven days and filter. The dose of Wine of Aloes is from 1 to 2 fl. drachms. 3849. Vinum Antimonii Wine of Antimony. Tartrate of Antimony and Po- tassium, 4 parts or 29 grains. Boiling Distilled Water, ... 60 parts or 1 fl. ounce. Stronger White Wine, suffici- ent to make 1000 parts or a pint. Dissolve the Tartrate of Antimony and Potassium in the Water, and, while the solution is hot, add 10 fl. ounces of Wine VINA — WINES. 999 and filter through paper, adding through the filter enough Wine to make the filtered liquid measure a pint. U. S. 1880. Vinum Antimoniale or Antimonial Wine. — Under this title the Br. P. directs Tartrated Antimony 1 part or 40 grains, Sherry 219 fl. parts or 1 pint Imperial (20 fl. ounces). Vinium Stibiatum of the G. P. is made with Tartrate of Anti- mony and Potassium I part, dissolved in Sherry Wine 250 parts. The dose of Wine of Antimony is from 5 to 15 minims for cough and bronchial troubles, and a fl. drachm as an emetic, repeated if necessary. 3850. Vinum Aromaticum. Aromatic Wine. Lavender, Origanum, Peppermint, Rosemary, Sage, Wormwood, Stronger White Wine, sufficient to make 100 parts or a pint. Mix the solid ingredients and reduce them to a coarse pow- der, moisten the powder with a fl. ounce of Stronger White Wine, pack it moderately in a conical glass percolator and gradually pour enough Stronger White Wine upon it to make the filtered liquid measure a pint. U. S. 1880. This is somewhat similar to the Vin Aromatique of the French Codex. each, .... 1 part or 72 grains. 3851. Vinum Aurantii. Br. Orange Wine. Wine made: in Britain by the fermentation of a saccharine solution to which the fresh peel of the Bitter Orange has been added. Br. This official Br. Wine is simply a Wine flavored with ( >range, and it seems unnecessary to be to so much trouble to prepare it. It may be readily prepared by adding a sufficient quantity of Tincture of fresh Orange Peel or a Solution of ( hi of Bit- ter ' Grange in Alcohol to Sherry or other White Wine. Orange Wane is used for making flavored medicinal Wines. 1000 VINA — WINES. 3852. Vinum Camphoratum. G. P. Wine of Camphor. Camphor, 1 part. Alcohol, 1 part. Mucilage of Acacia, 3 parts. White Wine, 45 parts. Dissolve the Camphor by rubbing with the Alcohol and gradually add the remaining ingredients. By using Water instead of Wine this maybe dispensed as Camphor Julep when wanted. 3853. Vinum Chinae. G. P. Wine of Cinchona. Tincture of Cinchona, 1 part. Glycerin, 1 part. Sherry Wine, 3 parts. Mix and set the mixture aside for three weeks, then filter. See, also, Wine of Calisaya (3875). Wine of Cinchona made from the alkaloids of the bark is generally preferred to this. 3854. Vinum Colchici Radicis. Wine of Colchicum Root. Colchicum Root, .... 40 parts or 13^ ounces av. Stronger White Wine, suf- ficient to make . . . 100 parts or 2 pints. Reduce the Root to a No. 30 powder, and moisten it with 6 fl. ounces of Wine, pack it moderately in a conical percolator, and gradually pour enough Wine upon it to make the filtered liquid measure 2 pints. U. S. 1880. This is a standard remedy for rheumatism and gout, the dose being 5 to 20 minims. The Br. P. directs Colchicum Corm (root), in No. 20 powder, 4 ounces av., to be macerated with 20 fl. ounces of Sherry, then pressed and strained through calico and sufficient Sherry added to make 20 fl. ounces. This is only about half the strength of the U. S. preparation. The dose is 10 to 30 minims. VINA — WINES. 1001 3855. Vinum Colchici Seminis. Wine of Colchicum Seed. Colchicum Seed, ... 15 parts or 4^ ounces av. Stronger White Wine, suf- ficient to make . . . 100 parts or 2 pints. Reduce the Seed to a No. 20 powder and macerate it for seven days with 30 fl. ounces of the Wine, then filter and add through the filter enough Wine to make 2 pints. U. S. 1880. This is given for Rheumatism, etc., the dose being 10 to 20 minims. The G. P. directs Colchicum Seed 1 part, to be macerated with Sherry Wine 10 parts, for eight days, then expressed and the liquid filtered. The dose is 10 to 30 minims. 3856. Vinum Ergotae. Wine of Ergot. Ergot, in No. 30 powder, 15 parts or 4^ ounces av. Stronger White Wine, sufficient to make . .100 parts or 2 pints. Moisten the powder with 10 fl. ounces of Stronger White Wine, pack it moderately in a cylindrical percolator and grad- ually pour enough Stronger White Wine upon it to make 2 pints. U. S. 1880. This preparation, which was formerly very much prescribed and used by physicians, is now but little employed, as the Fluid Extract is more concentrated and convenient. 3857. Vinum Ferri. Br. Wine of Iron. [ron Wire 1 ounce or 1 part. Shell)' 20 ll. ounces or 20 ll. parts. Macerate for 30 days in a closed vessel, the Iron being almost but not wholly immersed in the Win., and the vessel frequently shaken and the stopper removed, then filter. The dose is 1 to 4 fl. drachms. 1002 VINA — WINES. 3858. Vinum Ferri Amarum. Bitter Wine of Iron. Solution of Citrate of Iron and Quinine, . 8 parts. Tincture of Sweet Orange Peel 12 parts. Syrup, 36 parts. Stronger White Wine 44 parts. To make 100 parts. Mix and filter through paper. U. S. 1880. Few druggists keep the solution of Citrate of Iron and Quinine on hand, and if it is desired to make this preparation from the officinal formula or its equivalent, the scale salt, Citrate of Iron and Quinine may be used. The following is identical in composition with the officinal formula: Citrate of Iron and Quinine (soluble) . . 580 grains. Tincture of Sweet Orange Peel 4 fl. ounces. Syrup, 10 fl. ounces. Stronger White Wine, 16 fl. ounces. Water, sufficient to make 2 pints. To 1 ounce of hot Water, in an evaporating dish, gradually add the Citrate of Iron and Quinine, agitating it gently over a spirit lamp until the salt is dissolved, add the solution to the Tincture, then mix with the Syrup and Wine and add enough Water to make the measure 2 pints. This is unlike the Bitter Wine of Iron furnished by manu- facturers, being much stronger of both Iron and Quinine. See 3876. 3859. Vinum Ferri Citratis. Wine of Citrate of Iron. Citrate of Iron and Ammo- nium, 4 parts or 580 grains. Tincture of Sweet Orange Peel, 12 parts or 4^ fl. ounces. Syrup, 12 parts or 3 fl. ounces. Stronger White Wine, . . 72 parts or 23 fl. ounces. Mix and filter through paper. U. S. 1880. VINA — WINES. 1003 The Citrate of Iron should be dissolved in an ounce of warm Water before adding to the other ingredients. The Br. P. formula is Citrate of Iron and Ammonium 160 grains or I part, Orange Wine 20 fl. ounces or 55 fl. parts. Dis- solve and let the solution remain for three days in a closed vessel, shaking occasionally; afterwards filter. The dose is from a teaspoonful to a tablespoonful. Other soluble salts of Iron that are not precipitated by the acid of the Wine may be used. 3860. Vinum Ipecacuanhas. J Vine of Ipecac. Fluid Extract of Ipecac, . 7 parts or 2]^ fl. ounces. Stronger White Wine, . 93 parts or 30 fl. ounces. Mix them and filter through paper. U. S. 1880. The Br. P. formula is Ipecacuanha, coarsely powdered, 1 ounce, Acetic Acid 1 fl. ounce, distilled Water a sufficiency. Sherry 20 fl. ounces. Macerate the powder in the Acid for 24 hours, transfer to a percolator and pass sufficient distilled Water through it to produce 20 fl. ounces of the liquor, evapo- rate the product to dryness over a water-bath, powder the resi- due and macerate it in the Sherry for 48 hours, with occasional agitation, and filter. The G. P. directs 1 part of Ipecac to be macerated with 10 parts of Sherry Wine. It will be observed that the U. S. preparation represents 7 per cent., the Br. 5 per cent., and the German 10 per cent, of the drug. The dose is from 5 to 20 minims, as an expectorant, and from l to 3 fl. drachms, as an emetic. 3861. Vinum Opii. Wine of Opium. U. S. P. [870. Opium, in powder 960 grains. Cinnamon, in powdei 60 grains. Cloves, in powder 60 grains. Sluii}' Wine, sufficient to make .... a pint. 1004 VINA — WINES. U. S. P 1880. Powdered Opium, 829 grains. Cinnamon, in powder, 73 grains. Cloves, in powder, 73 grains. Stronger White Wine, sufficient to make a pint. To the mixed powders add 14 fl. ounces of the Wine and macerate the mixture for seven days, with occasional agitation, then transfer it to a filter and gradually pour enough Wine upon it to make the filtered liquid measure a pint. U. S. 1880. Although this preparation is now but seldom used, the dif- ference in the strength of Opium should be noted, the 1880 being about one third weaker than the 1870. The Br. P. directs Extract of Opium 1 ounce av., Cinnamon Bark, bruised, 75 grains, Cloves, bruised, 75 grains, Sherry 1 pint. Macerate for seven days in a closed vessel and filter. The dose is 10 to 40 minims. 3862. Vinum Pepsini. G. P. Wine of Pepsin. Pepsin, . . . 50 parts. Glycerin, 50 parts. Water, 50 parts. White Wine, 1845 parts. Hydrochloric Acid, 5 parts. Rub the Pepsin, Glycerin, and Water together to a thin paste, then add the Wine and Acid, set aside for six days, with occasional stirring, and filter. See also Wine of Pepsin (3883). 3863. Vinum Quininse. Br. Wine of Quinine. Sulphate of Quinine, . . 20 grains or 1 part. Citric Acid, 30 grains or \y 2 part. Orange Wine, .... 20 fl. ounces or 438 parts. Dissolve first the Citric Acid and the Quinine salt in the Wine, allow the solution to remain for three days in a closed vessel, shaking it occasionally, and afterwards filter. A fl. ounce contains I grain of Quinine. Dose, 1 to 2 table- spoonfuls. VINA — WINES. 1005 A formula for Quinine Wine was given in a former edition of FENNER'S FORMULARY, double the strength of this. It was Sulphate of Quinine 32 grains, Sherry Wine 12 fl. ounces, Alcohol 2 fl. ounces, Syrup 1 ounce, Soluble Flavoring 1 ounce. A tablespoonful contains 1 grain of Quinine. 3864. Vinum Rhei. Wine of Rhubarb. Rhubarb, No. 30 powder, . 10 parts or 730 grains. Calamus, No. 30 powder, . 1 part or 73 grains. Stronger White Wine, suffi- cient to make 100 parts or a pint. Moisten the mixed powders with 2 ounces of Stronger White Wine, pack the mixture in a conical glass percolator and grad- ually pour enough Stronger White Wine upon it to make the filtered liquid measure a pint. U. S. 18S0. The Br. P. formula is Rhubarb Root, in coarse powder, 1^ ounce av., Canella bark, in coarse powder, 60 grains, Sherry 20 fl. ounces. Macerate for seven days in a closed vessel, then strain, press, filter, and add Sherry to make 20 fl. ounces. 3865. Vinum Rubrum. Red Wine. The U. S. P. describes this as a deep-red alcoholic liquid, made by fermenting the juice of colored grapes in presence of their skins. It should contain not less than 10 nor more than 12 per cent., by weight, of Absolute Alcohol. 3866. Vinum Xericum. Sherry. This is a light-colored Spanish Wine, which was formerly directed to be used in the U. S. 1'.. and is still directed in the Br. P. [t contains a larger percentage of Alcohol than mosl Wines, about 17 per cent, being the avera Other varieties of Wine are also used for making the official preparations, the California and native Wines being consider- ably used. It is only required that they contain sufficient alcohol to keep the preparations. 1006 VINA — WINES. Other Medicinal Wines. The foregoing Wines are those official in the leading phar- macopoeias, but besides these are many unofficial medicinal Wines which are considerably used, the most important among them being known as elegant preparations. They are, there- fore, given the same prominence as the official Wines. 3870. Prepared Wine. For making medicinal Wines, containing organic salts or principles, or salts of Iron, it is necessary to use a Wine which is free fron tannin or astringent principles which will cause dis- coloration or precipitation. Many of the Wines, also, have not sufficient alcoholic strength to keep the preparations in which they are combined, and it is necessary to add more Alco- hol to them, as is directed for making the Stronger White Wine of the U. S. P. In making the following Wines, therefore, it is expedient to have a Prepared Wine which corresponds with these require- ments, as follows : White Wine, Sherry or native, .... 7 pints. White of Egg, 1 fl. ounce. Alcohol, 1 pint. Beat the White of Egg to a froth and mix it with the Wine, heat to about 170 F., or until the albumen is coagulated, then cool, add the Alcohol and, after standing a few hours, filter clear through paper. This serves as a basis for all the medicinal Wines which fol- low, and may with advantage be used in the official Wines foregoing in place of the Stronger White Wine directed. 3871. Aromatic Wine. Cinnamon, in fine powder, 1 ounce av. Nutmeg, in fine powder, 1 ounce av. Cloves, in fine powder, 1 ounce av. Soluble Flavoring, 2 fl. ounces. Prepared Wine, 2 pints. Macerate for 14 days and filter. Dose, a tablespoonful. VINA — WINES. 1007 3872. Wine of Beef. Leibig's Extract of Meat I ounce av. Elixir, 4 fl. ounces. Prepared Wine, 12 fl. ounces. Rub the Extract of Meat with the Elixir and add the Wine. After standing a few days, filter. A tablespoonful, which is the usual dose, represents 1 ounce of fresh beef. This preparation is really much more desirable than the pop- ular Wine of Beef and Iron, as the Iron is better in some other combination than with the beef. See remarks after Wine of Beef and Iron. 3873. Wine of Beef and Iron. Leibig's Extract of Meat, y 2 ounce av. Phosphate of Iron, in scales (1880), . 64 grains. (Other soluble salts of Iron may be used. ) Elixir, 4 fl. ounces. Prepared Wine, 12 fl. ounces. Rub the Extract of Meat with the Elixir, dissolve the Iron salt in about ]/ 2 fl. ounce of hot Water and add to the Wine. then mix the Wine with the mixture of Beef, etc., and set aside, agitating occasionally, for several weeks, then filter. A tablespoonful represents x / 2 ounce of fresh Beef and 2 grains of the Iron salt. In this preparation an action between the salts which arc contained in the Meat Extract, the acid of the Wine, and the sol- uble salt of Iron which is used, continues to take place for some time after the preparation is made, resulting in the reduction of a portion of the Iron salt to an insoluble salt (mainly ( >xide of Iron). This cannot be avoided in the preparation except by the introduction of undesirable agents, and the only way to make- a satisfactory Wine of Beef and Iron is to let it stand until the action is completed, before filtering, for, if filtered when freshly made, it will soon precipitate and continue to do so after repeated filtrations unless allowed to stand at least four weeks alter being made, when it should be filtered. 1008 3874. Wine of Beef, Iron, and Cinchona. Sulphate of Quinine, 5 grains. Sulphate of Cinchonidine, 10 grains. Wine of Beef and Iron, 1 pint. Rub the Sulphates with a portion of the Wine of Beef and Iron, add the remainder, and, after standing, filter. A dessertspoonful of this preparation represents about 10 grains of Cinchona in addition to the Wine of Beef and Iron. 3875. Wine of Calisaya. Wine of Cinchona. Sulphate of Quinine, 60 grains. Sulphate of Cinchonidine, 90 grains. Elixir, 2 pints. Prepared Wine, 6 pints. Mix the Wine and Elixir, rub the Sulphates first with a por- tion of the mixture, then add the remainder and color as desired with Caramel and Cochineal Red. A dessertspoonful, the usual dose, represents about 10 grains of Cinchona or Calisaya Bark. This may also be prepared from the bark if desired, by per- colating 1% ounce of the bark with the mixture of Elixir and Wine sufficient to make a pint of the preparation. Also, by mixing 1^ fl. ounce of Fluid Extract of Calisaya or Cinchona, either plain or detannated, with enough of the mixed Wine and Elixir to make a pint. The preparation made from the salts is, however, generally preferred, and is much less trouble to make than from the bark. 3876. Bitter Wine of Iron. Wine of Cinchona and Iron. The formula for this preparation is now official in the U. S. P., and is given, with suggestions, etc., on page 1002. It may be added here, however, that any soluble salt of Iron may be used, and an equivalent quantity of the salts of Cinchona added. VINA — WINES. 1009 We give the following formula, which will probably give better general satisfaction than those mentioned : Sulphate of Quinine, 60 grains. Sulphate of Cinchonidine 90 grains. Phosphate of Iron, in scales (1880), . 2 ounces av. Elixir 1 3-/ pint. Prepared Wine 6 pints. Water, '. y^ pint. Rub the Sulphates with the Elixir and add the Prepared Wine, dissolve the Iron salt in the Water by the aid of heat, and add the Solution of Quinine, etc., gradually to the Solution of Iron, with constant stirring, until they are thoroughly mixed, and filter if necessary. As thus prepared it will be a light, greenish-colored prepara- tion. It may be colored dark with caramel, or reddish-brown with caramel and cochineal red. If Citrate of Iron and Ammonium is used instead of the Phosphate, it imparts the desired color, but is more liable to precipitate after standing. It may be more highly flavored, if desired, by adding Soluble Flavoring. This preparation represents in a dessertspoonful, the usual close, about 10 grains of Cinchona and 2 grains of the Iron salt. 3877. Wine of Calisaya, Iron, and Strychnine. Wine of Cinchona, Iron, and Strychnine. Sulphate of Strychnine 1 '_< grain. Hitter Wine of 1 ron i pint. Dissolve the Strychnine salt by rubbing with separate por- tions of the Bitter Wine of Iron, or use Solution of Strych- nine (1942) 1 1 .. fl.drachm instead ol the salt. A fl.drachm contains ,,',„ grain of Strychnine combined with Bitter Wine of I ron. 3878. Wine of Coca or Erythroxylon. Coca Leaves, in coarse powder, 3 ounces av. Elixir ') fl.oum Prepared Wine 1 .: fl.oum 1010 VINA — WINES. Percolate the drug with the mixed Wine and Elixir until I pint is obtained. This may also be made by mixing 3 fl. ounces of Fluid Extract of Coca with a mixture of 2 parts of Prepared Wine and I part of Elixir, sufficient to make I pint. The dose is a teaspoonful to a dessertspoonful or more. 3879. Wine of Cotton Root or Gossypium. This is most readily prepared from the Fluid Extract, as follows : Fluid Extract of Cotton Root, ... 4 fl. ounces. Prepared Wine, 8 fl. ounces. Elixir, 4 fl. ounces. Mix them. As a portion of the properties of Cotton Root is insoluble except in Alcohol a precipitate forms, and the preparation must be filtered. This is given in doses of 1 to 4 fl. drachms as a uterine tonic. 3880. Wine of Damiana or Turneria. Fluid Extract of Damiana, . . . . . 3 fl. ounces. Prepared Wine, 10 fl. ounces. Elixir, 3 fl. ounces. Mix them and, after standing, filter. The dose is 1 to 4 fl. drachms as a diuretic and aphrodisiac. 3881. Wine of Iron. This may be prepared from any of the soluble salts of Iron. The following will give the best satisfaction : Phosphate of Iron, in scales (1880), . 256 grains. Elixir, 5 fl. ounces. Prepared Wine, 10 fl. ounces. Water, . ^ fl. ounce. Dissolve the Iron salt in the Water by the aid of heat and add to the solution, first, the Elixir, then the Wine, and, after standing, filter if necessary. A fl. drachm contains 2 grains of the Iron salt. The dose is a teaspoonful or more. VINA — WINES. 1011 3882. Wine of Pancreatin. Powdered Pancreatin 160 grains. Elixir, 4 fl. ounces. Prepared Wine, 12 fl. ounces. Soluble Flavoring l / 2 fl. ounce. Mix them and macerate for several days, with occasional agita- tion, then strain through muslin or filter through coarse paper. This may also be prepared by macerating fresh Pancreas of the pig, chopped fine, with a mixture of Prepared Wine and Elixir, in the same proportion as above, using 1 pint of the mixture to half a pound of the chopped pancreas. A tablespoonful of this Wine represents 5 grains of Pancre- atin. The dose is a dessertspoonful to a tablespoonful. 3883. Wine of Pepsin. The formula for this Wine is given among the official prep- arations, but the product prepared from it does not correspond with that usually found on the market by that name, which may be made as follows : Pepsin, in scales, 256 grains. Hydrochloric Acid, 30 minims. Distilled Water, ill. ounce Prepared Wine, 1 5 fl. ounces. Rub the Pepsin to a coarse powder and macerate with the Water until it softens to a gelatinous mass, then add the Hydrochloric Acid and the Prepared Wine, and agitate occa- sionally until the Pepsin is dissolved, and strain through mus- lin. Do not filter. This is the most effective Wine of Pepsin, but, as it is not sweetened nor flavored, it is not so pleasanl as the following : Saccharated Pepsin 256 grains. Elixir 4 ll. ounces. I [ydrochloric Acid 15 minims. Soluble flavoring | . fl.ounce. Prepared \\ ine 12 flounces. Mix and macerate, with occasional agitation, for several days, then strain or filter through coarse paper. 1012 VINA — WINES. Wine of Pepsin may also be made by macerating the freshly dissected inner coating of the pig's stomach with Prepared Wine. When thus made there is no very definite strength to the preparation, but the general rule is to use one stomach to make a pint of the preparation. The dose of Wine of Pepsin is from a teaspoonful to a tablespoonful. Combinations of Wine of Pepsin with Bismuth are adver- tised by manufacturers, but they cannot be prepared except by neutralizing the Wine which is used, and the Elixirs of Pepsin and Bismuth are more desirable. 3884. Wine of Pepsin and Iron. Phosphate of Iron, in scales (1880), . . 128 grains. Wine of Pepsin, 1 pint. Dissolve the Iron salt in ]/ 2 fl. ounce of Water and add to the Wine of Pepsin. A dessertspoonful contains 2 grains of the Iron salt. 3885. Wine of Tar. Pine Tar, 1 ounce av. Pine Sawdust, 2 ounces av. Elixir, ! 4 fl. ounces. Prepared Wine, sufficient to make . . a pint. Rub the Tar in a mortar with the Pine Sawdust, mix the Elixir with 12 flounces of the Prepared Wine and rub with the Tar, etc., in a mortar, filter and add through the filter sufficient Prepared Wine to make 1 pint. 3886. Vitalized Wine. Phosphorus, yi grain. Absolute Alcohol, 1 fl. ounce. Glycerin, 1 fl. ounce. Phosphate of Iron, 64 grains. Prepared Wine, 14 fl. ounces. Dissolve the Phosphorus in the Absolute Alcohol by means of a water-bath, add the Glycerin, then the Wine, dissolve VINA — WINES. 1018 the Iron salt in the y 2 fl. ounce of Water and add to the solution. The dose is a dessertspoonful to a tablespoonful. 3887. Wine of Wild Cherry. Fluid Extract of Wild Cherry. ... 2 fl. ounces. Glycerin, 1 fl. ounce. Elixir, 4 fl. ounces. Prepared Wine, sufficient to make . . 1 pint. Mix them and, after standing 24 hours, filter. This may also be prepared by percolating the bark with the liquids, or by crushing 2 ounces of Wild Cherry Pits and mac- erating with the mixture of Elixir. Wine. etc.. sufficient to make 1 pint. The dose is a dessertspoonful. 3888. Wine of Wild Cherry and Iron. As the Wine of Wild Cherry, prepared from the bark, con- tains considerable astringent or tannin, it will not combine with Iron without making an inky mixture, except it is detan- nated, which may be done as directed (515). The preparation may then be made as follows: Wine of Wild Cherry, detannated, . . 1 pint. Phosphate of Iron, in scales (1880), . .128 grains. Dissolve the Iron in l / z fl. ounce of hot Water and add to the Wine. As the detannated Wine of Wild Cherry contains little else of the medicinal properties of the bark except the Hydrocy- anic Acid and flavoring Ingredients, a preparation which answers the purpose may be made from the following formula: Oil of Cherry Laurel Leaves 15 minims. Hydrocyanic Acid, diluted, U. S., . . 30 minims. Phosphate of Iron, in scales 1 i38o), . .128 grains. Glycerin 1 11. ounce Elixir, \ il.MMi, Prepared Wine, to make 1 pint. Dissolve the Iron sail in % fl.ounce of hoi Water and add to the mixed Wine, Glycerin, and Elixir, then add the Acid and 1014 V IN A — WINES. Oil, mixing them thoroughly together, color with Caramel and, after standing a few days, filter. Other soluble salts of Iron may be used instead of the Phosphate. Other Medicinal Wines. But few Medicinal Wines, except those already noted, are now used in medicine.* Wine was once a favorite vehicle for exhausting medicinal prin- ciples and the administration of medicine, but has now given way to more stable and uniform alcoholic liquids. A few Wines that are now occasionally called for are noticed as follows : 3889. Antiscrobutic Wine — (Paris Codex). — Fresh Horseradish Root 3 ounces, Scurvygrass 1% ounce, Watercress Leaves \]4. ounce, Buckbean 1% ounce, Mustard Seed \ l /z ounce, Chloride of Ammonium 5^ drachms, Wine 5 pints. Compound Spirit of Scurvygrass 1% ounce. Macerate for 14 days, drain, and express. 3890. Wine of Comfrey Compound — Restorative Wine Bitters — (Amer. Disp.). — Comfrey Root, Solomon's Seal Root, Helonias Root, each in coarse powder, 1 ounce, Chamomile Flowers, Colombo Root, Gentian Root, Cardamom Seed, Sassafras Bark, each in coarse powder, y 2 ounce. Sherry Wine 4 pints, boiling Water a sufficient quantity. Pour boiling Water upon the drugs in a covered vessel, sufficient to cover them, let macerate 24 hours, then add the Wine, macerate for 14 days, express, and strain. 3891. Wine of Gentian Compound — Bitter Wine Tonic. — This may be prepared by mixing 4 fl.drachms of Fluid Extract of Gentian Compound with 4 fl. ounces of Elixir and 12 flounces of Prepared Wine. A Bitter Wine of Iron may be made by adding 1 28 grains of Phosphate of Iron to this preparation. This is desirable for some purposes, for example, it may be combined with Iodide of Potassium, while the Bitter Wine of Iron made from Cinchona salts is not compatible with it. 3892. Wine of Golden Seal Compound — (Amer. Disp.). — Golden Seal Root, Tulip Tree Bark, Biiterroot, each in fine powder, 1 drachm, Prickly- Ash Berries, Sassafras Bark, Capsicum, each in fine powder, ]/ 2 drachm, Sherry Wine 3 pints. Macerate 14 days and filter. Dose, a tablespoonful. 3893. Wine of Hellebore Compound — (Amer. Disp.) — Black Hellebore, in coarse powder, Logwood, ground, Helonias Root, in powder, each 2 ounces, Sherry Wine sufficient to make \ l / 2 pint. Uterine tonic, etc. Dose, tablespoonful or more. 3894. Simple Wines of Drugs.— Wines may be made from many roots barks, leaves, flowers, etc., by macerating the substances, in coarse powder, with Sherry or other Wine, or by adding their fluid extracts to Wine. The proportion is usually 1 ounce in a pint of Wine, for ordinary preparations, and a less quantity of more powerful drugs. ZINCUM — ZINC. 1015 ZINCUM — ZINC. Symbol, Zn ; Atomic weight, 64.9; Sp. gr. 6.8 to 7.2. This elementary metal was known to the ancient metal- workers, but was first introduced to notice by Paracelsus in the 16th century. It is obtained by roasting its ores, by which it is volatilized, its vapor being collected in suitable receivers under water. It is a bluish-white metal, tough and ductile when cold, brittle and easily pulverized when heated to about 400 F. ; is fused at ;~$ I\, and burns with a bright green flame when heated to 941 F. in contact with the air. It is grouped with Aluminium, Cereum, and Cadmium, as it resem- bles them in physical properties. In the arts it is one of the most important metals, being extensively used in the man- ufacture of a great variety of useful and ornamental articles, and, combined with copper, forming brass and other alloys, which are of great importance. In pharmacy Zinc is the source of several important salts which are used in medicine and for other purposes. The official salts of Zinc are as follows: 3895. Zinci Acetas. Acetate of Zinc— White Vitriol. Zn(C s H s ( > 8 ) 8 .3H 2 ( >. This is official in nearly all countries. Tin Br. 1'. formula for preparing it is : Carbonate of Zinc 2 ounces av. Acetic Acid, 5 fl. ounces or a sufficiency. Distilled Water <> ll. ounces. Add the Carbonate of Zinc, in successive portions, to 3 ounces of the Acetic Acid, previously mixed with the Water in a flask-, heat gently, add by degrees the remainder of the A.< id till the Carbonate is dissolved, boil for a few minutes, filter while hot and set it aside for two days to crystallize. The crystals may be removed and more obtained by concentrating the liquid. The crystals arc drained and dried on porous tiles. Uses. — This salt is used for injection-, and washes, and is given as a tonic in doses of 1 to 2 grains, and as an emetic in ol io to 20 grains. 1010 ZINCUM — ZINC. 3896. Zinci Bromidum. Bromide of Zinc. ZnBr. This is official in the U. S. P. The formula is not given, but it may be made by double decomposition between Bromide of Potassium and Sulphate of Zinc, as follows : Bromide of Potassium, . . . 100 parts or grains. Sulphate of Zinc, 240 parts or grains. Dissolve them, each separately, in the smallest requisite quantity of hot Water and mix the solutions while hot, when the mixture is cool add twice its volume of Alcohol, filter through asbestos to separate the Sulphate of Potassium, which is precipitated, and evaporate the filtered liquid to dryness and granulation. Uses. — This salt of Zinc is given as a hypnotic in doses of 5 grains. 3897. Zinci Carbonas Praecipitatus. Precipitated Carbonate of Zinc. (ZnC0 3 ) 2 .3Zn(HO) 2 . Impure Carbonate of Zinc is known as Calamine, and is frequently directed in older pharmaceutical works ; but the precipitated salt is now generally used in medicine. The U. S. P. gives no formula for Precipitated Carbonate of Zinc, but the Br. P. directs : Sulphate of Zinc, 10 ounces av. Carbonate of Sodium, 10^ ounces av. Boiling Distilled Water, a sufficiency. Dissolve the Carbonate of Sodium in a pint of the Water in a capacious porcelain vessel and pour into it a solution of the Sulphate of Zinc, in 20 fl. ounces of the Water, stirring dili- gently ; boil for 15 minutes after effervescense has ceased and let the precipitate subside, decant the supernatant liquid, pour on the precipitate 60 fl. ounces of boiling distilled Water, agitat- ing briskly ; let the precipitate again subside and repeat the washing with hot distilled Water until the washings give no ZINCUM — ZINC. 1017 precipitate with Chloride of Barium, then drain and dry the precipitate. Uses. — This is considerably used externally in the form of ointment and washes, and is the working basis of many other of the Zinc salts. Calamine is used in making ointments and in injections, etc. 3898. Zinci Chloridum. Chloride of Zinc. ZnCl 2 . Commercial Chloride of Zinc is prepared by adding Zinc to Hydrochloric Acid and Water as long as it will dissolve, then evaporating until it will solidity. The pure salt is made by the Br. P. formula as follows: Granulated Zinc 16 ounces av. Hydrochloric Acid 44 fl. ounces. Solution of Chlorine, a sufficiency. Carbonate of Zinc, q. s., about . . }4 ounce av. Distilled Water,' 20 fl. ounces. Put the Zinc into a porcelain basin. ,n\(.\ by degrees the Hydrochloric Acid, previously mixed with the Water, and aid the action by gently warming on a sand-bath until gas is no longer evolved, boil for half an hour, supplying the Water lost by evaporation, and allow to stand on a cool part of the sandbath for 24 hours, stirring frequently. The liquid is then tested for iron <>r lead, which air removed, if present, by the Solution of Chlorine and the Carbonate of Zinc. It is then filtered and evaporated to a liquid which solidifies when cold, and moulded, granulated, or otherwise put u]) for convenient use. For many purposes it is unnecessary t<> make .1 chemically pure salt as above directed. Ordinary Chloride of Zinc may be made by dissolving Zinc t<> saturation in Hydrochloric Arid and evaporating the solution to dryness. Uses. Chloride of Zinc is considerably used as an antisep- ti< ,[])i\ disinfectant. It is .\\^<> employed .is an escharotic, and is a favorite application to war: nc< 3, etc. 1018 ZINCUM — ZINC. 3899. Zinci Iodidum. Iodide of Zinc. Znl 2 . This may be prepared by digesting granulated Zinc in excess with Iodine diffused in Water in a manner similar as is directed for making Iodide of Iron. (See page 506.) Uses. — This is given as an alterative in doses of y 2 to 2 grains. 3900. Zinci Oxidum. Oxide of Zinc. ZnO. The Br. P. directs to place Carbonate of Zinc, 6 ounces, in a loosely-covered Hessian Crucible and expose it to a dull red heat until a portion, taken from the centre of the contents of the crucible and cooled, no longer effervesces when moistened with Water and dropped into diluted Sulphuric Acid. The Carbonic Acid and Water are expelled by the heat. Uses. — Commercial Oxide of Zinc is extensively used for a paint base and for many industrial purposes. Pure Oxide of Zinc is used extensively in powder and in the form of Oint- ment. It is also an ingredient in face powders, liquid cosme- tiques, etc. 3901. Zinci Phosphidum. Phosphide of Zinc. Zn 3 P 2 . This may be made by fusing Zinc in a properly constructed apparatus and passing over the melted mass vapors of Phos- phorus in a current of dry Hydrogen until the Zinc is con- verted into a Phosphide. It is only made by manufacturing chemists. Uses. — Phosphide of Zinc is a nerve stimulant and aphro- disiac, largely given for nervous debility and loss of vital power. It is safer and less irritating than Phosphorus. The dose is from ^ to J 8 grain in powder or in pills. 1019 3902. Zinci Sulphas. Sulphate of Zinc. ZnS0 4 7H 8 0. The U. S. P. gives no formula for preparing this salt, but the Br. P. directs as follows : Granulated Zinc 16 ounces av. Sulphuric Acid 12 fl. ounces. Distilled Water 8o fl. ounces. Solution of Chlorine, a sufficiency. Carbonate of Zinc. ^ ounce av., or a sufficiency. Pour the Sulphuric Acid, previously mixed with Water, on the Zinc contained in a porcelain basin, and when efferves- cense has nearly ceased aid the action by heat. A few drops of the liquid may then be tested for Iron by adding excess of Ammonia and then Sulphydrate of Ammo- nium, when a black precipitate will be produced if Iron is present. For commercial Sulphate of Zinc it is unnecessary to remove it, but if a pure salt is desired the solution may be freed from it by adding the Solution of Chlorine until the liquid acquires a permanent odor of Chlorine, then add, with continued agitation, the Carbonate of Zinc until a brown pre- cipitate appears and all the Iron is precipitated, then filter, evaporate until a pellicle forms on the surface and crystallizes. Uses. — Sulphate of Zinc is an astringent and tonic much used for injections, eye-water, washes, etc.. and internally as an astringent in doses of I to 1 grains, and as an emetic in doses of io to 30 grains. 3903. Zinci Sulphocarbolas. Sulphocarbolate of Zinc. /ml,ILS<>. | L,.M.,<>. This sail is official in the Br. and (i. 1'., and may l><- mad. by heating a mixture "i" Carbolic Arid and Sulphuric Acid, saturating tin- product with Oxide of Zinc, evaporating and crystallizing. Uses. — It i- used a. anastringenl and antiseptic, chiefly for lotions, injection . etc. L020 /ixcum — zinc. 3904. Zinci Valerianas. Valerianate of Zinc. Zn(C 5 H 9 2 ) 2 .H 2 0. This is official in the U. S. or Br. P., the formula in the lat- ter being as follows: Sulphate of Zinc, 53^ ounces av. Valerianate of Sodium 5 ounces. Distilled Water, a sufficiency. Dissolve the Sulphate of Zinc and the Valerianate of Sodium, each separately, in 40 fl. ounces of Water, heat both the solutions to near the boiling point, mix them, cool, and skim off the crystals which are produced, evaporate the mother liquor, at a temperature not exceeding 200 F., till it is reduced to 4 fl. ounces, cool again, remove the crystals which form, and add to those before obtained, drain on filter paper, wash with a little cold distilled Water, drain and dry. Uses. — This salt is used as a nervine and antispasmodic in doses of 1 to 3 grains. 3905. Zincum Granulatum. Granulated Zinc. The Br. P. directs this to be made from Zinc of commerce, 1 pound, by heating it in an earthern crucible, and immedi- ately, when the metal is fused, remove the crucible from the fire and pour the fluid in a thin stream into a vessel containing about 2 gallons of cold Water. Drain off the Water and dry the granulated Zinc. This is the most convenient form for metallic Zinc to be used for pharmaceutical purposes. Other Salts of Zinc. Besides. the foregoing salts of Zinc, which are official in the leading pharmacopoeias, a few others are occasionally used, and are here mentioned. 3906. Cyanide of Zinc — Zn(CN)„. — Prepared by adding Hydrocyanic Acid to Solution of Acetate of Zinc and collecting the precipitate. This is used as a nervous sedative in doses of }4 to 14 grain. ZINCUM — ZINC. 1021 3907. Cyanide of Zinc and Potassium.— By dissolving Cyanide of Zinc in a solution of pure Cyanide of Potassium, concentrating, and crystallizing. 3908. Ferrocyanide of Zinc — Zn. 1 (C. < X 3 ) 4 Fe 2 . — By mixing Solutions of Sulphate of Zinc and Ferrocyanide of Potassium, collecting and washing the precipitate. 3909. Lactate of Zinc— Zn (C a H 6 O g ) 8 .3H 8 0.— By dissolving Carbon- ate of Zinc to saturation in diluted Lactic Acid, concentrating and crys- tallizing. 3910. Salicylate of Zinc — Zn(C 7 H 5 8 ) g .3H g O. — By heating Salicylic Acid with distilled Water and gradually adding Oxide of Zinc, suspended in Water, until no more will dissolve, then filtering, concentrating, and crys- tallizing. 391 1. Tartrate of Zinc. — This may be prepared by mixing hot concen- trated Solutions of Sulphate of Zinc and Neutral Tartrate of Potassium, col- lecting the precipitate and drying. 3912. Zinc-Ethyl, etc.— Zinc also combines with the organic bases form- ing liquid salts, which take fire spontaneously when exposed to the air. Zinc-Ethyl, Zinc-Methyl and Zinc-Amyl are examples of these substances, but they have no use except as chemical curiosities. The foregoing formulas, comprising Part [II. of this volume, include- most of the preparations, official and unofficial, which are known or required in the regular practice of pharmacy in this country. The pages which follow will be devoted to the consideration of special lines of preparations, which, though not essential to the practice of pharmacy,are closely connected with its interests. PART IV. ♦ • • THE STANDARD REMEDIES AND PROPRIETARY MEDICINES. The following formulas are designed for making a complete line of Standard Proprietary Remedies, which may be prepared and put up by druggists, or others, for local trade or for the market. It is well known to all who are conversant with the business that the making of Proprietary or " Patent " Medicines requires no knowledge nor facilities which are not ready at hand or readily obtainable by the average druggist. With reliable formulas and outfits of wrappers, cartoons, and labels, which may now be had specially designed for the purpose,* druggists may prepare and put up a line of Proprietary medicines or articles, such as they may select, with but a slight outlay and with an abundant reward in the way of profits. It is needless to urge the advantages to druggists of putting up and furnishing, as far as is possible, their own " Patent" Medicines in place of manufacturers. The profit of several hundred per cent., the reputation which naturally comes of putting before the people their own preparations, the constantly increasing trade in this line, and the satisfaction of furnishing reliable articles worth the money, should be inducement enough for any enterprising druggist to make the attempt to run a line of his own preparations. The formulas which follow in this department are mainly original, and intended to make preparations similar to those which have been best received or which possess the greatest merit. They are not, however, given as the exact formulas of particular proprietary prepa- rations now in the market or made by any particular manufacturer. * For further information on this subject, address the author, 1022 STANDARD PROPRIETARY REMEDIES. 1023 Some formulas, not original, for old and well-known preparations, are also given as selected from the best authorities. Besides the formulas given in this section, many others that may be put up as proprietary remedies are given in various departments of this work, and may be found by referring to the index. 3913. Acid Phosphate. Nerve and System Vitalizer. A proprietary preparation known as Fforsford's Acid Phosphate, put up by the Rumford Chemical Works, Providence, R. I., has had a large sale in this country. The title "Acid Phosphate" is claimed by them as a trade mark. Several formulas for \cid Phosphate have been given in the preceding pages (577, 753), but for conve- nient reference formulas are also given in this department. Solution Phosphate Compound, concentrated (1938), i pint. Water 4 pints. Mix them and, after standing, filter. This corresponds very nearly with the supposed composition of the preparation above named, which is said to contain in each tl. drachm 3 grains Phosphate of Calcium, '_> grain Phosphate of Iron, ' .. grain Phosphate of Magnesium, l /i grain Phosphate of Potassium, with excess of Phos- phoric A* id. Liquor Acidi Phosphorici Comp. (with Iron), which is put up by manufacturing pharmacists, is of about the same composition. The dose of this preparation is from ' _• to 1 teaspoonful in sweet- ened water after each meal and before retiring. It is also extensively used at the soda fountain, making an agree able acid addition to fruit syrups, etc. AGUE CURES. The Proprietary Remedies for Ague which are found on the market consisl of syrups, solutions or tinctures, mixtures and pills. They are given for 'lulls and fevers, ague, neuralgia, malaria, etc. The syrups are the most palatable of any ol the Ague Cures, but arc hss effe< live than the stronger remedies prepared in the form of tin. lures, mixtures and pills. All Ague < lures depend for their value upon the proper combination of antiperiodics and alteratives, both being essential, the former to "break " the chills, and the latter to stimulate the organs to throw oil the diseased matter with which they have become loaded. The following are representative of the ]()24 STANDARD PROPRIETARY REMEDIES. different varieties of Ague Preparations which are found in the market : 3914. Ague Cure or Syrup. For Chills, Fever and Malaria. Sulphate of Quinine, 128 grains. Sulphate of Cinchonidine, 128 grains. Diluted Sulphuric Acid, q. s., about . . 3 fl. drachms. Alcohol 2 fl. ounces. Oil of VVintergreen 10 minims. Fluid Extract of Sarsaparilla Compound, . 2 fl. ounces. Water, 5 fl. ounces. Sugar 14 ounces av. Mix the Sulphates with the Water, add sufficient of the acid to dissolve them. Add the Oil of Wintergreen to the Alcohol and add the solution to the solution of the Cinchona Salts. Then add the Fluid Extract of Sarsaparilla, mix them thoroughly, and after stand- ing a few days, filter and dissolve the Sugar in the filtrate by agita- tion. A fi. drachm contains 2 grains of Cinchona Salts. The dose is a teaspoonful to a tablespoonful for ague and chills. 3915. Ague Remedy or Tincture. For Chills, Fever and Malaria. Purified Chinoidin, 1 ounce av. Extract of Liquorice in powder, .... % ounce av. Fluid Extract of Podophyllum 1 fl. ounce. Fluid Extract of Leptandra 1 fl. ounce. Alcohol, 10 fl. ounces. Oil of Eucalyptus 2 fl. drachms. Water sufficient to make a pint. Dissolve the Chinoidin, and Oil of Eucalyptus, in the Alcohol mixed with the Fluid Extracts, by maceration. Dissolve the Liquor- ice Extract in 3 fi. ounces of Water by the aid of heat, and add to the solution of Chinoidin, etc., add enough Water to make a pint, and, after standing a few days, filter. This is a dark colored, very strong and bitter preparation, acting as a cholagogue and antiperiodic. It is very effective. A lighter colored, more pleasant preparation may be made by using 1 ounce of Quinine Sulphate instead of the Chinoidin. The dose is from a teaspoonful to a tablespoonful. STANDARD PROPRIETARY REMEDIES. 1025 3916. Ague Mixture or Cholagogue. This mixture is similar to several preparations on the market known as Cholagogues. It is an unsightly compound, as it contains quite a precipitate, but is very effective. Sulphate of Quinine % ounce av. Sulphate of Cinchonidine, '•: ounce ax- Fluid Extract of Stillingia, 3 fl. ounces. Fluid Extract Leptandra 1 fl. ounce. Fluid Extract Podophyllum }& fl. ounce. Fowler's Solution of Arsenic )\ fl. ounce. Oil of Wintergreen, 1 fl. drachm. Syrup, sufficient to make 1 pint. Rub the Sulphates with the Fluid Extracts, add the Oil and then mix thoroughly with the Syrup and Solution of Arsenic. A fl. drachm contains about 3^4 grains of the Cinchona Salts. The dose is y& teaspoonful to a dessertspoonful, for chills. This is similar to the proprietary Osgood's Indian Cholagogue, which has been a popular ague cure for nearly half a century. 3917. Ague and Neuralgia Pills. Chinoidin, purified 150 grains. Podophyllum Resin (Podophyllin) 5 grains. Leptandrin, 10 grains. Capsicum, in powder, 20 grains. Mix the ingredients thoroughly and make 100 pills. The dose for children is 1 or 2 pills, for adults 2 to 4 pills, every 3 hours between chills. 3918. Ague and Neuralgia Pills. Sulphate of Quinine 5° grains. Sulphate of ( :inchonidine 50 grains. Irsenious Acid 2 grains. Sulphate of Strychnine, '.• grain. Podophyllum Resin (Podophyllin), . ... 20 grains. Leptandrin 60 -rains. Extra* t of I dandelion, q. s. to make a mass. Mix thoroughly and make into 100 pills. The dose for 1 hildren is 1 to 2 pill's, for adults 2 to 4 pills. 1026 STANDARD PROPRIETARY REMEDIES. ALTERATIVES. Although most of the Blood Purifiers and Sarsaparillas on the market are also known as Alteratives, a few preparations which are supposed to have an especially alterative action on the various organs of secretion are known particularly as Alteratives. The following are representative of this class of preparations : 3919. Alterative Compound. Blood and Liver Syrup. Stillingia, in No. 40 powder, 8 ounces av. Sarsaparilla, in No. 30 powder, .... 8 ounces av. Burdock Root, in No. 30 powder, ... 3 ounces av. Blue Flag Root, in No. 20 powder, ... 1 1 /?, ounce av. Mandrake, in No. 50 powder, i^4 ounce av. Senna, in No. 20 powder, 1% ounce av. Prickly-Ash Bark, in No. 50 powder, . . % ounce av. Sarsaparilla Flavoring, ... ... % ounce av. Diluted Alcohol, 4 pints. Sugar, 5 pounds av. Water, a sufficient quantity. Mix the drugs, moisten them with 2 pints of diluted Alcohol and macerate in a covered vessel in a warm place for 24 hours, transfer to the water-bath percolator, pack moderately, pour upon . them 2 pints of diluted Alcohol and set in a warm place for one day ; then heat moderately and, after one hour, begin to percolate slowly, add- ing Water to the drugs after the liquid has ceased to drop, and con- tinuing the heat and percolation until ^/z pints have passed. To this add the Sarsaparilla Flavoring and, after standing a few days, filter, adding through the filter enough Water to make 5/2 pints, then dissolve the Sugar in the filtrate by agitation and add, if nec- essary, Water sufficient to make 1 gallon of the preparation. One ounce Iodide of Potassium may be added if desired. This is an excellent alterative compound, which may be put up under many names — as Blood Purifier, Sarsaparilla Alterative, Med- ical Discovery, etc. The dose is from 1 to 2 teaspoonfuls, three times a day. Many other formulas of similar composition will be found under other headings throughout this work. This preparation may be put up under the title designated in the heading, or under other names, as Sarsaparilla Compound, Blood Purifier, or other similar titles. STANDARD PROPRIETARY REMEDIES. 1027 3920. Alterative Extract or Juice. ("Succus Alteraus.") The original formula for this preparation was introduced by Geo. W. McDade, M. D., of Montgomery, Ala., who obtained it from the Creek Indians. (?) It is claimed to be prepared from the fresh green medicinal plants, each pint bottle containing the "unimpaired" virtues of 16 troyounces of the true medicinal plants Stillingia Sylvatica, Smilax Sarsaparilla, Phytolacca Decan- dra, Lappa Minor, and Xanthoxylum Carolinianum. It is fur- nished to the trade by Eli Lilly & Co., of Indianapolis, Ind. It is, of course, impracticable for druggists to obtain the fresh plants, which are claimed to compose the original article; but a good Alterative Extract may be made from the following formula, the ingredients of which are mentioned in the'McDade prescription: Stillingia Root, 24 ounces av. Sarsaparilla Root, 24 ounces av. Poke Root, 8 ounces av. Burdock Root, 16 ounces av. Southern Prickly-Ash Lark, 4 ounces av. Alcohol, 6 pints. Glycerin, 1 pint. Water, sufficient to make 1 gallon. Grind the drugs to a coarse powder, moisten them with 3 pints of Alcohol mixed with 2 pints of Water and macerate for 24 hours in a covered vessel, then transfer to a water-bath percolator, pack firmly, pour on the remainder of the Alcohol (3 pints) mixed with 3 pints of Water, and set in a warm place fur one day ; then heal moderately and, after one hour, begin to percolate, adding Water to the drugs, and continuing the heat and percolation until 7 pints of percolate are obtained. Continue the percolation with Water until 4 [)ints more have passed, evaporate this to a soft extract, add to it the Glycerin and the - pints of percolate previously obtained and, after standing a few days, filter. The dose is a teaspoonful to a dessertspoonful, three times a day. ANODYNES. Two kinds of Anodyne preparations may he made and put up as proprietary medicines. Those containing Ether, like Hoffman's Anodyne, which do not have a bad after effect, and those containing 1028 STANDARD PROPRIETARY REMEDIES. Opium, Morphine, or Chloral, which, though effective, are unsafe preparations to introduce. The term Anodyne is also used in con- nection with many other preparations, as " Tolu Anodyne " for coughs, " Clove Anodyne " for toothache, etc., but these will be fount! under other headings. Formulas are only given for the etherial and harmless Anodynes. If desired, the formulas for others will be found under other depart- ments. See preparations of Opium, Chloral, Cocaine, etc. 3921. Golden Anodyne Tincture. A preparation similar to Hoffman's Anodyne, of a yellow or gol- den color; is considerably in demand among the Germans, under the name " Golden Tincture." Various formulas have been given for preparing it, the following being as satisfactory as any : Ether, Sulphuric, 1 ounce. Alcohol 2 ounces. Tincture Tumeric, sufficient to color. Or it may be colored with Fustic Wood, by maceration. This is in effect the same as Hoffman's Anodyne, but is more attractive. The dose is 10 to 60 minims, for pain, cramp, etc. Another -formula is Ether 1 ounce, Laudanum 1 ounce, Chloro- form l /{. ounce, Alcohol 1 ounce, colored with Tincture Turmeric. 3922. Anodyne Elixir. Pain-Soothing Cordial, without Opium or Choral. An Anodyne without Opium or Chloral is desirable and valuable, yet there is no such preparation found in the market. The follow- ing is recommended to those who desire to put up such a prepara- tion. It is effective and at the same time harmless : Bromide of Potassium 2 ounces av. Sugar, 5 ounces av. Ether (Sulphuric), 1 fi. ounce. Alcohol, 2 fl. ounces. Tincture of Hyoscyamus, 3 fl. ounces. Elixir, 3 fl. ounces. Water, 4 flounces. Dissolve the Bromide of Potassium and the Sugar in the Water, mix the Ether with the Alcohol, add the Tincture of Hyoscyamus, then the Elixir and, having mixed them, add the Solution of STANDARD PROPRIETARY REMEDIES. 1029 Bromide of Potassium and Sugar to the mixture and mix them thoroughly. A fi. drachm contains about 7 grains Bromide of Potassium, 4 minims of Ether, and 12 minims of Tincture of Hyoscyamiis. It may be given in doses of a teaspoonful to a dessertspoonful, every hour, or, in severe cases of colic, cholera morbus, etc., a teaspoonful every 15 minutes until relieved. As the Ether in this preparation, although adding much to its effectiveness, is rather disagreeable, its place may be supplied with x% fl.drachms of Chloroform, or it may be omitted altogether. Other Anodyne preparations will be found under other headings, as Chlorodyne, Sedatives, Nervines, etc., etc. ASTHMA REMEDIES. The Asthma Remedies which are put up as Proprietary are in various forms, as powders and pastilles for burning slowly, the smoke being inhaled, cigarettes for smoking, remedies to take, and inhal- ants. The design of most of them is to produce diaphoresis ami expectoration as well as to subdue the spasmodic action of the inflamed bronchial organs. The following formulas make prepara- tions representative of the various remedies - 3923. Asthma Remedy. A Powder for Fumigation. Grindelia Robusta, in fine powder, 8 ounces. Jaborandi Leaves, in line powder, -S ounces. Eucalyptus Leaves, in fine powder, .... 4 oun< 1 5. Coca Leaves, in line powder, 4 ounces. Digitalis Leaves, in fine powder, 4 ounces. Cubeb, in line powder, 4 ounces. Stramonium Leaves, in fine powder r 6 ounces. Nitrate of Potassium, in fine powder 12 ounces. Cascarilla Bark, 1 ounce. Mix the powders and dry them thoroughly before putting up. This is used by burning a. half teaspoonful or more on a piece of saitpctn- paper and inhaling the sm<>ke which rises, it affords prompt relief ami will i am- cases nol too far advanced. It is also excellent for catarrh, hay-fever, and other troubles of the nasal pas- sages, throat, and lungs. 1030 STANDARD PROPRIETARY REMEDIES. 3924. Asthma Cure. A Liquid to Take. Fluid Extract Grindelia, 3 fl. ounces. Fluid Extract Skunk Cabbage, 1 fl. ounce. Fluid Extract Lobelia, ... . . . . 1 fl. ounce. Fluid Extract Bloodroot, 2 fl. drachms. Fluid Extract Senega, . 2 fl. drachms. Chloroform, 4 fl. drachms. Alcohol, 20 fl. ounces. Water, .... 6 fl. ounces. Mix them thoroughly and, after standing, decant or filter. This may also be prepared from the drugs Grindelia 3 ounces, Skunk Cabbage, Lobelia, each 1 ounce, Senega and Bloodroot, each 2 drachms, percolated with a mixture of 4 measures of Alcohol with 1 measure of Water, sufficient to make 2 pints, and Chloroform 1 fl. ounce, added to the tincture. The dose is a teaspoonful, in sweetened water, every 15 to 30 minutes, when the attack of asthma comes on, until relieved. It should also be continued, in small doses, three times a day to effect a cure. 3925. Asthma Relief. To take for Asthma, Hay Fever, etc. Nitrite of Amyl, 2 fl. drachms. Iodide of Potassium, 1 ounce av. Elixir, 1 pint. Mix and dissolve. The dose is a teaspoonful for Asthma, at the first indications of the paroxysm, repeated every 20 or 30 minutes until relieved. For Hay Fever, Influenza, etc., a teaspoonful every 3 or 4 hours. 3926. Asthma Inhalant. To be used by Inhalation. Nitrite of Amyl, 2 fl. drachms. Essential Oil of Mustard, 10 drops. Ether, Sulphuric, Y? fl. ounce. Alcohol, 4 fl. ounces. Mix them. Put a few drops of the liquid upon some cotton or sponge, hold in the hand and inhale the vapor. It is still better to STANDARD PROPRIETARY REMEDIES. 1031 put the cotton loosely in a glass tube or homeopathic bottle with the bottom out and inhale by drawing the air through the tube. This gives immediate relief. Other forms of inhalers may be used. 3927. Asthma Pastilles. Benzoin, in fine powder, . 1 ounces av. Jaborandi, in fine powder, .2 ounces av. Stramonium Leaves, in fine powder, ... 4 ounces. Xitrate of Potassium, in fine powder, ... 4 ounces. Charcoal, 20 ounces. Mucilage of Tragacanth, thin, sufficient. Beat the powders with the mucilage to a stiff mass and roll out into a cake about % inch thick, cut this into strips -/% inches wide and 1% inches long and dry by warm air. One end of the pastil is ignited and the smoke inhaled until re- lieved. 3928. Asthmatic Cigarettes. Stramonium Leaves, 4 ounces. Cascarilla Bark, }4 ounce. Lobelia Leaves, 2 drachms. Mullein Leaves, . . 4 ounces. Cut the leaves and drugs fine like smoking tobacco and make into cigarettes. This may also be smoked in a pipe. BALMS OR PANACEAS. In proprietary medicines Balms are remedies intended for internal or external use, and designed to allay pain, colic, cholera morbus, inflammation, etc. The following will be found satisfactory and similar in composition to those most popular in the market, known as Magic Balms, Pain Killers, Ready Reliefs, Magic Oils, etc. They are as a class hot, stimulating preparations, increasing the action of the parts with which they come in contact, or acting as counter- irritants, and thus, on the Indian principle, frightening away the disease. They are sold as general panaceas for pain, etc. Many other similar preparations for external and internal use will be found among the Liniments and under other headings. The sale for tins class of preparations as proprietary medicines is as large as of nearly any other class, and they may readily be prepared by druggists, affording a good profit. 103-2 STANDARD PROPRIETARY REMEDIES. 3929. Eucalyptus Balm. Oil of Eucalyptus 1 fl. ounce. Oil of Cloves X A-ounce. Oil of Hemlock, y> fl. ounce. Capsicum, y> ounce av. Camphor, y 2 ounce av. Alcohol, 1 pint. Mix them, macerate for a week or ten days, agitating occasionally, and filter. 3930. Magic Balm. Oil of Sassafras, . 1 fl. ounce. Oil of Cloves, y fl. ounce. Oil of Hemlock, y 2 fl. ounce. Chloroform, }i fl. ounce. Ether, y fl. ounce. Capsicum, y ounce av. Camphor, x / 2 ounce av. Water of Ammonia, y> fl. ounce. Alcohol, 1 pint. Mix them. Macerate for a week or ten days, agitating frequently and filter. 3931. Magnetic Balm. Oil of Sassafras, 1 fl. ounce. Oil of Peppermint, .... .... % fl. ounce. Oil of Hemlock, 1 fl. ounce. Capsicum, y ounce av. Camphor, y 2 ounce av. Alcohol, .... 1 pint. Mix them. Macerate for a week or ten days, agitating frequently and filter. 3932. Pain Cure Balm or "Pain Killer." Guaiac Resin, 1 ounce av. Capsicum, y 2 ounce av. Camphor y% ounce av. Opium, in powder, 60 grains. Water of Ammonia, % fl. ounce. Alcohol, 1 pint. STANDARD PROPRIETARY REMEDIES. 1033 Mix them. Macerate for a week or ten days and filter. This is similar to some of the Pain Killers. The preparation known as Xo. 6. or Tincture of Myrrh and Cap- sicum (3646), is often put up as a Pain Killer. 3933. Ready Balm or "Ready Relief." Camphor, y 2 ounce av. Capsicum, y? ounce av. Oil of Turpentine, % fl. ounce. Water of Ammonia, U. S. P., .... 5 fl. ounces. Alcohol, ... 12 fl. ounces. Dissolve the Camphor and Oil of Turpentine in the Alcohol, add the Capsicum and Ammonia, and after standing a week or ten days, filter rapidly. This is similar to Ready Relief. It should be given internally only in small doses, 10 to 20 minims. 3934. Wizard Balm. Oil of Cajuput, y fl. ounce. Oil of Sassafras, 1 fl. ounce. Oil of Hemlock, %. fi.ounce. Oil of Origanum, %. fl. ounce. Oil of Cedar, yk fl. ounce. Capsicum, % ounce av. Camphor, % ounce av. Chloroform % fl. ounce. Alcohol, 1 pint. Mix them. Macerate for a week and filter. BALSAMS. Many proprietary preparations, called " Balsams," are classed with other remedies, as " Cough Balsam" or " Lung Balsam," among the cough remedies; "Carminative Balsam," " Diarrhoea Balsam," etc., under cholera cures, etc. Others are included under other headings throughout the book. The few remaining unclassified, and known more particularly as Balsams, because they resemble the liquid Balsams, are noted in tins department. Several Balsams, also, which are put up as proprietary remedies, will be found on pages [83 to [86, which see. 1034 STANDARD PROPRIETARY REMEDIES. 3935. Anodyne Balsam. Castile Soap, 1 ounce. Opium Tincture, 3 ounces. Camphor, 3 drachms. Alcohol, 10 ounces. Cut the soap in fine pieces and digest, by gentle heat, with the Tincture of Opium and Alcohol until dissolved, then add the Cam- phor, dissolve and filter. This is for external use for swellings, pain, etc. 3936. Canker Balsam. Marsh Rosemary Root, in coarse powder, . 4 ounces av. Borax, in powder, 1 ounce av. Glycerin, 6 ounces av. Alcohol, 12 fl. ounces. Water, a sufficient quantity. Mix Alcohol and Water, equal measures, and percolate the Marsh Rosemary Root with the liquid until it ceases to drop, then add suf- ficient Water through the percolator to make 27 fl. ounces of the percolate, dissolve the Borax in the liquid, add the Glycerin, and .filter if necessary. This is an astringent liquid, useful as a gargle for sore throat, a mouth wash, etc., and as an application for cracked nipples or other similar sores. 3937. Caustic Balsam. A preparation known as Gombaulfs Caustic Balsam has had an extensive sale for veterinary use, etc. The following formula makes a preparation quite similar to the proprietary article : Sulphuric Acid (by weight), 1 ounce av. Oil of Turpentine, 6 fl. ounces. Croton Oil, 1 fl. ounce. Corrosive Sublimate, 60 grains. Camphor, ^ ounce. Cotton Seed Oil, 8 fl. ounces. Mix the Oils of Turpentine and Croton, add the Corrosive Sub- limate, in fine powder, and the Camphor, and dissolve ; then add, a little at a time, the Sulphuric Acid, taking care that the mixture does not become too hot, and, when all has been added and the mixture has become cool, add the Cotton Seed Oil, and mix them thoroughly. This is used for sprains, ringbones, strains, swellings, puffs, etc. STANDARD PROPRIETARY REMEDIES. 1035 3938. Locatelle's Balsam. Yellow Wax, 4 ounces. Olive Oil, 1 pound. Venice Turpentine 1 pound. Alkanet Root, 2 ounces. Steep the Alkanet Root for several days in the Olive Oil and strain, melt the Wax, add the Oil and the Turpentine and mix them well together. This is used as a pectoral in doses of Y? to 1 teaspoonful. 3939. Thibault's Balsam. Myrrh, Aloes, and Dragon's Blood, each . . 1 drachm. St. John's Wort Flowers, 1 ounce. Spirit of Wine (Alcohol), 10 ounces. Canada Balsam, ^2 ounce. Digest the Flowers in the Spirit for three days, then express the liquor and dissolve in it the other ingredients and, after standing, filter. This is used as a healing Balsam for wounds, cuts, etc., and is given as a diuretic and for kidney and bladder troubles, gonorrhea, etc., in doses of a teaspoonful or more. 3940. Turlington's Balsam. Benzoin, 12 ounces. Storax (liquid), 4 ouni es. Balsam Peru, ... 2 ounces. Myrrh, 1 oun< e. Aloes, .... 1 ounce. Balsam Tolu 4 ounces. Extract Liquorice, 4 ounces. Angelica Rool ' 2 ounce. Alcohol 1 gallon. Reduce the gums to a coarse powder and macerate all together with the Spirit for two weeks, with agitation, then filter. This has been a popular panacea for internal and external use. 3941. Vegetable Healing Balsam. White Resin 1 pound av. < >il of Turpentine, 1 pint. Melt the Resin, remove it from the fire and add the Oil of Tux« pentine, mixing them well together. 1036 STANDARD PROPRIETARY REMEDIES. This is similar to Peckham's Balsam, as it is now put up and sold, as a proprietary medicine. It is used for coughs and colds, also for kidney and bladder troubles, in doses of 3 to 10 minims or more. It is also used externally on sores, wounds, swellings, etc. The following is said to be the formula from which this Balsam was formerly prepared : Pale Resin 3 pounds, melted and strained ; then add Oil of Turpentine 2 pints, Balsam of Tolu 1 ounce, Balsam of Fir 4 ounces, Oil of Hemlock, Oil of Origanum, A 7 enice Turpen- tine, each 1 ounce, Strained Honey 4 ounces. Mix well together. Similar " Vegetable Healing Balsams'" are also prepared by oth- ers and sold under similar names. The following formulas may be used : Burgundy Pitch, 1^ pound av. Oil of Turpentine, 1 pint. Melt the Pitch, remove from the fire and gradually add the Oil of Turpentine, mixing them well together. Resin, 1 pound. Venice Turpentine, 1 pound. Oil of Turpentine, 1 pint. Melt the Resin, add the Venice Turpentine, warm together and add the Oil of Turpentine while cooling. Resin, 1 pound. Balsam Fir, % pound. Venice Turpentine, ^ pound. Oil of Turpentine, 1 pint. Melt the Resin, add the Balsam Fir and Venice Turpentine, warm together, and when cooling, add the Oil of Turpentine, mixing them well together. BITTERS. A great variety of Bitters are sold under various names as propri- etary medicines. They are designed for various uses, and may nat- urally be divided into three classes, as follows : Class A. These Bitters are weakly medicinal preparations designed to be taken in large doses, and depend for their effect more upon the liquor which they contain than the other medicinal ingredients. STANDARD PROPRIETARY REMEDIES. 1037 They are stimulating Bitters, and are to a great extent substitutes for liquors, although if properly used are very beneficial for disor- dered digestion, dyspepsia, malaria, etc. The most popular Bitters of this class found in the market are known as Hostetter's, Drake's, Wahoo, Niagara, etc. The following formulas make good prepara- tions of this kind. Other formulas will be found on pages 436 to 439- 3742. Stomach Bitters. Bitter Orange Peel, 2 drachms. Wahoo Bark, 2 drachms. Sweet Flag Root, 1 drachm. Cinnamon Bark, 1 drachm Cloves, 10 grains. Coriander, 30 grains. Whisky, 6 pints. Sugar, 2 ounces Water, . . , 2 pints. Reduce the drugs to a coarse powder and macerate with the Whisky and Water for several days, until the strength is obtained, then filter. If desired, Cologne Spirit (Alcohol .proof ) may be diluted with an equal quantity of Water and used instead of Whisky. The dose is from half to a wineglassful or more. 3943. Hop Bitters. * Hops, in coarse powder 3 ounces av. Buchu, in coarse powder 1 ounce av. Dandelion Root, in coarse powder, . . . 1 ounce av. Mandrake Root, in coarse powder, . . ,80 grains. Bitter Orange Peel, in coarse powder, . . 2 drachms. Wahoo Dark 1 drachm. Whisky 5 pints. W ater, q. s., or 3 '_• pints. Mix the Whisky with 3 pints of Water and macerate the drugs with the mixture for several days, then filter and add through the filter enough Water to make the measure a gallon. The dose is a tablespoonful to a wineglassful or more. This is much stronger of the medicinal ingredients than the pro prietary H<>p Bitters. [1 may l"- reduced with diluted Cologne Spirit. 1038 STANDARD PROPRIETARY REMEDIES. 3944. Wahoo Bitters. Wahoo Bark, in coarse powder, ..... x /z ounce. Sweet Flag Root, in coarse powder, ... % ounce. Cinnamon Bark, in coarse powder, . . . . 1 drachm. Cardamom Seed, in coarse powder, .... 20 grains. Oil of Orange (fresh), 10 drops. Whisky, 6 pints. Water, 2 pints. Glycerin, , 1 ounce. Mix and macerate for several days, then filter. Dose, from half to a wineglassful or more. Other Bitters of this class may be made in the same general way by using other bitter drugs, other liquors or other flavoring ingredients. 3945. Plantation Bitters. Wild Ginger Root, y 2 ounce. Bitter Orange Peel, . 1 ounce. Dandelion Root, 1 ounce. New England Rum, 1 pint. Whisky, 5 pints. Sugar, .............. 4 ounces. Water, .............. 2 pints. Reduce the drugs to a coarse powder and macerate with the mixed liquids for a few days, then filter. Bitters — Class B. This class of Bitters includes those in which iron is combined with bitter tonics, aromatics, etc., in the form of a pleasant cordial. Iron Bitters have, of late, by the reason of extensive advertising, become quite popular, and, although they are nothing new in the line of preparations, they now have a large sale, and, as they may be made at a low cost, are quite profitable to put up. In making these Bitters it is necessary to use tonics and aromatics which do not make an inky color or taste with the iron salts. 3946. Iron Bitters. Tonic Health Cordial. Wahoo Bark, in coarse powder, ..... 1 ounce av. Cardamom Seeds, in coarse powder, ... 2 drachms. Caraway Seeds, in coarse powder, .... 2 drachms. STANDARD PROPRIETARY REMEDIES. 1039 Coriander Seeds, in coarse powder, ... 2 drachms. Nutmeg, in coarse powder, 1 drachm. Oil of Orange, fresh, 1 fl. drachm. Oil of Cassia (Cinnamon) 10 minims. Citrate of Iron and Ammonium, . . . . 1 ounce aw Sugar, 1 pound aw Cologne Spirit (deodorized Alcohol), ... 2 pints. Water, sufficient to make 1 gallon. Mix the powdered drugs and macerate them with the Alcohol, with frequent agitation, for several days, then pour off the liquid, add the oils to the tincture and reserve. Now add 2 pints of Water to the macerated powders, agitate, let stand 12 hours and pour off ; repeat with the same quantity of Water, adding the aqueous liquids to the alcoholic solution and mixing them thoroughly ; dissolve the Iron salt and the Sugar in enough Water to make, when added to the mixed liquids, 1 gallon of the mixture, and, after standing a few days, filter clear. This may be made, also, by mixing 1 fl. ounce of Fluid Extract of Wahoo with 3 fl.ounces Compound Tincture of Cardamom and the other ingredients as directed in the formula above. ( )ther soluble salts of Iron may be used instead of the citrate. The dose is a dessertspoonful to a wineglassful. 3947. Iron Tonic Bitters. Sulphate of Quinine, 40 grains. Sulphate of Cinchonidine, 80 grains. Citrate of Iron and Ammonium, . . 512 grains. Cologne Spirit 2 pints. Essence of Calamus 1 fl. ounce. Soluble Elixir Flavoring, 6 fl.ounces. Water, 5/2 pints. Sugar, )i pound av. Mix the ingredients, dissolve and filter. This is similar to Bitter Wineof Iron except that it contains no Wine. Tlie dose is a dessertspoonful to a wineglassful, Many other preparations may be put up and sold as "Iron Bitters," or " Iron Tonic Bitters," and by other titles. The Elixirs of Calisaya and Iron, Gentian and Iron, and other tunic Elixirs containing iron, may be diluted one-half for this purpose with Alcohol 1 part, Syrup 1 part, and Water a parts. 1040 STANDARD PROPRIETARY REMEDIES. 3948. Iron Wine Bitters. Bitter Wine of Iron is frequently put up and sold as Iron Bitters, but is stronger than most that are put up for general sale. The fol- lowing makes a good Iron Bitters, using Wine as the menstruum : Citrate of Iron and Quinine, 1 ounce av. Essence of Calamus, 1 fl. ounce. Oil of Cinnamon, 10 minims. Oil of Orange, 40 minims. Sugar, 8 ounces av. Water (hot) 4 fl. ounces. Alcohol 1 pint White Wine (Sherry or Angelica), . . . 6^ pints. Dissolve the Citrate of Iron and Quinine in the hot Water and add the solution to the Wine, dissolve the Oils in the Alcohol and add the Essence, then mix the solutions, dissolve the Sugar in the mixture and, after standing, filter. The dose is a dessertspoonful to a wineglassful. Class C. In this class the formulas are given for the stronger medicinal Bitters, similar to proprietary Bitters, which have been or are popu- lar. They differ from the other classes of Bitters by being put up in smaller packages, containing more of the medicinal agents and being taken in smaller doses. 3949. Blood Bitters, or Burdock Bitters. Tonic System Renovator. Burdock Root, 12 ounces av. Mezereum Bark, 2 ounces av. Wild Cherry Bark, 2 ounces av. Senn-a Leaves, . 2 ounces av. Columbo Root, 1 ounce av. Sassafras Bark, 2 ounces av. Liquorice Root, 2 ounces. Cinnamon, y 2 ounce av. Cloves, %. ounce av. Sugar, 4 ounces. Alcohol, 4 pints. Water, a sufficient quantity to make 1 gallon. Grind the drugs to coarse powder, mix the Alcohol with 3 pints of Water, moisten the powder with a pint of the mixture and macerate, STANDARD PROPRIETARY REMEDIES. 1(141 in a warm place, in a covered vessel for 24 hours ; transfer to the water-bath percolator, pour upon it 2 pints of menstruum, pack mod- erately, and set in a warm place for one day, then heat very moder- ately and, after one hour, begin to percolate, adding the remainder of the menstruum, and then Water to the drug, and continuing the heat and percolation until a gallon of the Bitters is obtained, dis- solve the Sugar in the liquid and filter. This may be made by cold percolation, but this method does not so thoroughly exhaust the drugs. The dose is from 1 to 2 teaspoonfuls three or four times a day. This is similar to, but a better preparation than, several of the Blood Bitters in the market. 3950. German Liver Bitters. Leptandra (Culver's Root), 8 ounces av. Mandrake Root, 2 ounces av. Burdock Root, 6 ounces av. Liquorice Root, 2 ounces av. Sassafras Bark, 2 ounces av. Cinnamon Bark, ]/?, ounce av. Alcohol, 4 pints. Water, a sufficient quantity. Grind the drugs to a coarse powder, mix the Alcohol with 4 pints of Water, moisten the powder with a pint of the menstruum and macerate in a covered vessel for 24 hours ; transfer to the water- bath percolator, pack firmly, pour upon it 2 pints of the menstruum and set in a warm place for one day, then heat moderately and, after one hour, begin to percolate, adding the remainder of the men- struum, and then Water to the drugs, and continuing the heat and percolation until a gallon of the Hitters is obtained ; filter. This may be made, also, by cold percolation, but this process dors not so thoroughly exhaust the drugs. The dose is from 1 to 2 teaspoonfuls three or four times a day. This is similar to the German Hitters and Liver Invigorators that have been popular. The preparation is a good liver and blood remedy. A great variety of other similar preparations are put up and sold under various names, all of them being intended to acl on tin- liver to increase its secretion of bile, thereby acting as laxative. The sale of this kind of Hitters is much less than it was formerly, but they are, nevertheless, good preparations. 1042 STANDARD PROPRIETARY REMEDIES. 3951. Jaundice or Laxative Bitters. Cape Aloes, in powder, 2 ounces av. Carbonate of Potassium (Sal Tartar), . . y 2 ounce. Culver's Root, in powder, 2 ounces av. Cinnamon, in powder, 1 ounce. Anise, in powder, 1 ounce. Coriander, in powder, 1 ounce. Liquorice Root, in powder, 2 ounces. Alcohol, 2 pints. Water, a sufficient quantity to make . . . 1 gallon. Mix the drugs and macerate them with the Alcohol and 6 pints of Water for seven days, then pour off the supernatant liquid, put the drugs in a percolator, pour the liquid upon them and percolate, add- . ing Water through the percolator until a gallon of Bitters is obtained, and filter. This is similar to several Laxative and Jaundice Bitters on the market, which have had a popular sale. 3952. Poor Man's Bitters. A class of Bitters made with a small percentage of Alcohol, and put up usually in half-pint bottles, to retail at 25 cents, are known by the above title, and by various other names. They are neither very profitable nor satisfactory proprietary medicines, but may be made, if desired, as follows : Quassia, ground, 4 ounces. Orange Peel, ground, 1 ounce. Cloves, in powder, % ounce. Cinnamon, in powder, % ounce. Alcohol, iy 2 pint. Water, q. s., about 7 pints. Mix the powders with the ground drugs and, having mixed the Alcohol with \y 2 pint of Water, moisten the drugs with 6 flounces of the mixture and pack in the water-bath percolator, pour upon them the remainder of the mixed Alcohol and Water and, after 24 hours, heat moderately for one hour and percolate, adding Water through the percolator to make 1 gallon of the Bitters ; after stand- ing, filter clear. The close is a tablespoonful or more. Mandrake Bitters may be made by adding 2 ounces of Mandrake to the above. STANDARD PROPRIETARY REMEDIES. llMo 3953- Vinegar Bitters. A proprietary medicine known as " Vinegar Bitters " at one time had a large sale, the result of extensive advertising as a " no vile fancy drink" and other temperance mottoes. It had the reputation of being a pharmaceutical compound (?) of Aloes and sour Beer. A Vinegar Bitters of much value, but entirely unlike the prepara- tion mentioned, may be made as follows : Cascara Sagrada Bark 6 ounces. Leptandra Root, 2 ounces. Mandrake Root 1 ounce. Cinnamon, )A ounce. Allspice, y<2 ounce. Good Wine or Cider Vinegar, . . . . 4 pints Alcohol, 1 pint. Water, 4 pints. Grind the drugs to a coarse powder and infuse them with the Vinegar at a temperature of about 200 F. for four hours, then pour off the liquid, pour the Water upon the dregs, and infuse as before; mix the liquors obtained, add the Alcohol and. after standing, strain. This is a good laxative and liver regulator. Other forms of Bitters will be found under other headings. 3954. Bitters in Powder. Gentian, in fine powder 4 ounces. Golden Seal, in fine powder, 4 ounces. Black Cohosh, in fine powder, 2 oun< es. Rhubarb, in fine powder, 1 ounce. Cinnamon, in fine powder, y 2 ounce. Nutmeg, in fine powder, 1 ounce. Aloes, in line powder 1 ounce. Bicarbonate of Sodium y? ounce. Ginger, iri fine powder, % ounce. Mix thoroughly. This is to be put up in boxes, or p 1 about 1 which sell gene-rally for 25 cents. The contents of the package is to be put into •; oi a pint of Water, and >^ pint of Alcohol, and a tablespoonful is to be taken before meals. 1044 STANDARD PROPRIETARY REMEDIES. A much cheaper Bitters Powder, which has had a good sale under various names, may be made with Aloes, in fine powder, 8 ounces. Canella, in fine powder, 8 ounces. Lupulin, in fine powder, ^ ounce. Cassia, in fine powder, y 2 ounce. Mix them. To take, prepare as above, using only half the quan- tity of the powder BLOOD PURIFIERS. Remedies for purifying the blood are mostly included under other headings, as Alteratives, Bitters, Sarsaparillas, etc. A few only of such as are known by the title of " Blood Purifiers " are given here. 3955. Blood Purifier. Burdock Root, 8 ounces av. Stillingia, 8 ounces av. Sarsaparilla, 8 ounces av. Senna Leaves, 4 ounces av. Sassafras Bark, 2 ounces av. Iodide of Potassium, 1 ounce av. Oil of Wintergreen, 20 minims.. Sugar, 1 pound av. Alcohol, 3>2 pints. Water, sufficient to make a gallon. Grind the drugs to a coarse powder, and, having mixed a pint of the Alcohol with a pint of Water, macerate them for 24 hours with the liquid ; then pack in a percolator, mix the remaining 2^ pints of Alcohol with an equal measure of Water and pour upon the drugs ; set in a warm place for 24 hours, then percolate slowly, add- ing Water to the drugs after the liquid has all disappeared from the surface", and continuing the percolation until 7^2 pints have passed. Dissolve the Oil of Wintsergreen in half an ounce of Alcohol and add the solution, with the Sugar and Iodide of Potassium,' to the percolate ; dissolve and filter. The dose is a teaspoonful to a tablespoonful. This may be put up as Blood Purifying Bitters, Blood Cleanser, or by any other similar title. STANDARD PROPRIETARY REMEDIES. 1045 3956. Blood Purifying Tea. Burdock Root, cut, 4 ounces. Blue Flag Root, cut, 1 ounce. Dandelion Root, cut, 3 ounces. Sassafras Bark, cut, . . 1 ounce. Sarsaparilla Root, cut, 4 ounces. Wild Cherry Bark, cut, 2 ounces. Yellow Dock Root, cut, 1 ounce. Mix thoroughly and put up in packages of about 2 ounces. Directions for preparing : Steep the contents of the package in a quart of Water, with gentle heat, for two hours, strain off 1 }A pint into a quart bottle and add half a pint of Alcohol and 4 ounces of Sugar. The dose is a wineglassful for adults, before meals and at bedtime ; children in proportion, according to age. CARMINATIVES. Carminatives are a class of mild, aromatic astringent preparations intended to be used for diarrhoea, summer complaints and like dis- orders. They are particularly adapted to children, being mild, pleasant to take, and effective. Other preparations of a similar nature will be found under other headings. See also Cholera Cures, Dysentery Remedies, etc. 3957. Blackberry Carminative. Blackberry Juice, 4 pints. Tincture of Opium, 3 fl. ounces. Fluid Extract of Blackberry, 8 fl. ounces. Fluid Extract of Wild Yam, . . ... 2 fl.oun Oil of Cinnamon, 30 minims. Oil of Nutmeg, 20 minims. Oil of Sassafras, 30 minims. Sugar, 2 pounds av. Alcohol, 2 pints. Water, sufficient to make 1 gallon. Mix the Fluid Extracts with the Juice and dissolve the Sugar in the mixture by agitation. Dissolve the oils in the Alcohol and add to the mixture, then add enough Water to make a gallon of the preparation and, after Standing a few days, filter. Dose, for children, from half to a traspoouful ; for adults, from a teaspoonful to a tablespoonful. 1046 STANDARD PROPRIETARY REMEDIES. 3958. Carminative Cordial. Catechu, 4 ounces av. Opium, 1 ounce av. Camphor, y 2 ounce av. Oil of Peppermint, 1 fi. drachm. Oil of Cinnamon, 20 minims. Oil of Cloves, 20 minims. Sugar, 2 pounds av. Alcohol, 2 pints. Water, sufficient to make 1 gallon. Macerate the Catechu, Opium and Camphor, with iJ-3 pints of Alcohol, mixed with 2 pints of Water for seven days, agitating every day, pour off the liquid and reserve ; pour the drugs upon a filter and percolate them with Water until 3 pints of percolate have been obtained, mix this with the reserved liquid ; dissolve the Oils in the remaining half pint of Alcohol, and add to the mixture, then filter, dissolve the Sugar in the filtrate, and add enough Water, if necessary, to make a gallon of the finished product. Dose, for children, from half to a teaspoonful ; for adults, a tea, spoonful to a tablespoonful. 3959. Ginger Carminative. Jamaica Ginger, in No. 40 powder, .... 6 ounces ay. Blackberry Root, in No. 40 powder, 1 pound av. Cinnamon, in No. 50 powder, 1 ounce av.. Nutmeg, in No. 50 powder, 1 ounce av. Sassafras, in No. 40 powder, 1 ounce av. Tincture of Opium, 4 fi. ounces. Sugar, 2 pounds av. Alcohol, 3 pints. Water, sufficient to make 1 gallon. Mix the powdered drugs and, having mixed the Alcohol with 3 pints of Water, moisten the drugs with 2 pints of the liquid and macerate in a closed vessel for 24 hours ; then pack in a percolator, pour the remainder of the liquid upon it and, after standing one day, percolate, adding Water through the percolator after the liquid has disappeared from the surface, and continuing the percolation until 6 pints are obtained ; add the Tincture of Opium and filter, and to the filtrate add the Sugar and, after the Sugar is dissolved, enough Water to make a gallon. Dose, for children, from half to a teaspoonful ; for adults, a tea- spoonful to a tablespoonful. STANDARD PROPRIETARY REMEDIES. 1047 CATARRH REMEDIES. Besides the general remedies which are taken for catarrh, which will be found under other headings, as Alteratives, Blood Purifiers, Tonics, etc., there are several preparations designed for application, to be used by insufflation or to be applied in the form of an ointment. They are as follows : 3960. Catarrh Remedy — Liquid. Fluid Extract of Hydrastis (Aqueous) or " Fluid Hydrastis," 3 fl. ounces. Carbolic Acid, 2 drachms. Sulphate of Zinc, 4 drachms. Sulphate of Morphine, ... . . 10 grains. Glycerin, 8 fl. ounces. Water, 5 fl. ounces. Mix them. To use, put 1 teaspoonful of common salt in a small cup of water, add 1 teaspoonful or more of the Remedy and use by insufflation or with a douche. This also makes an excellent gargle for sore throat, etc. 3961. Catarrh Remedy — Powder. Golden Seal, in fine powder, 4 ounces. Chlorate of Potassium, in fine powder Sulphate of Zinc, Sulphate of .Morphine, ... Salicylic Acid, 1 ounce 2 drachms, o grains. o grains. Mix them well together. A teaspoonful <>\ this powder and 2 teaspoonfuls of salt added to a pint of boiling water makes a liquid to be used with a douche or by insufflation. 3962. Camphorated Cream Salve. For Catarrh, Etc. Camphor, in coarse powder, . ... . . 80 grains. Carbolic Acid, 60 grains. Oil of Eucalyptus 2 fl. drachms. Tincture of Aconite Root, 2 ll. drachms. Yellow Wax . 2 mimics aw Petrolatum, r 6 ounces av. 1048 STANDARD PROPRIETARY REMEDIES. Melt the Wax and Petrolatum, mix the Camphor, Carbolic Acid, Oil of Eucalyptus, and Tincture of Aconite, and, when the Camphor is dissolved, add the mixture to the melted mass while cooling. This may also be used as an ointment for chilblains, chaps, etc., and when- ever a soothing, healing ointment is desired. 3963. Catarrh Cream Balm. Tincture of Aconite, 2 fi. drachms. Carbolic Acid (crystals), 1 drachm. Oil Sassafras, 30 minims. White Pine Turpentine, 2 drachms. Yellow Wax 2 ounces av. Petrolatum, 16 ounces. Melt the Wax, Turpentine, and Petrolatum together and, when cooling, add the Tincture, Carbolic Acid, and Oil, mixing them well together. 3964. Catarrh Cure or Salve. Oil of Tar, 30 minims. Oil of Sassafras, 1 fl.ounce. Oil of Eucalyptus, 2 fl.drachms. Oil of Peppermint, 10 minims. Tincture Aconite Root, 2 fl.drachms. Yellow Wax, 2 ounces av. Petrolatum, 16 ounces av. Melt, and make in the same manner as the preceding. 3965. Catarrh Snuff. Catarrh Snuff, which was once a popular proprietary remedy, has now become of slow sale. The following formula will be sufficient: Euphorbium, in very fine powder, .... % ounce. Bismuth Subnitrate, y 2 ounce. Salicylic Acid, ^ ounce. Oil of Wintergreen, 30 minims. Scotch Snuff, 15 ounces. Mix them by rubbing the Oil of Wintergreen with a portion of the Snuff, adding the Euphorbium and Salicylic Acid, and then mixing with the remainder of the Snuff. STANDARD PROPRIETARY REMEDIES. 1(49 CATHARTICS AND LAXATIVES. A great variety of preparations designed to act as laxatives or cathartics are found among proprietary medicines, most of them, however, under some other title. The following are specially rep- resentative of this class of preparations, but others, which act as cathartics or laxatives, will be found under other headings. See Elixirs, Tinctures, Syrups, etc. 3966. Buckthorn Cordial. Cathartic or Laxative Elixir, A cathartic or laxative remedy — something for constipation and the many disorders that proceed from it — is as frequently called for as any patent medicine on the druggist's shelves. Cathartic or Lax- ative Elixirs, under various names, have been considerably called for of late, and are rapidly taking the place of pills and other physic. The following has been thoroughly triecLand is recommended : Buckthorn Bark, 16 ounces av. Rochelle Salts, 8 ounces av. Senna Leaves, 8 ounces av. 'Liquorice Root, 4 ounces av. Ginger Root, 2 ounces av. Sweet Flag Root, 1 ounce av. Coriander Seed 2 ounces av. Oil of Wintergreen, 5 minims. Oil of Peppermint, . . 10 minims. Diluted Alcohol, 6 pints. Sugar, 2 pounds av. Water, a sufficient quantity to make . . . 1 gallon. Grind the drugs together to a coarse powder, moisten them with 2 pints of diluted Alcohol and macerate in a covered vessel for 24 hours, then transfer to the water-bath percolator, pack moderately, pour upon them the remaining 4 pints <>!" diluted Alcohol and set hi a warm place for 24 hours ; then heat moderately and, after one hour, begin to percolate, adding Water to the drugs after the liquid has disappeared from the surface, and continuing the heat and per- colation until 7 pints are obtained. In this percolate dissolve the Rochelle Salt> and the Sn^ar. add the < >ils. previously dissolved in L050 STANDARD PROPRIETARY REMEDIES. half an ounce of Alcohol, and, after standing a few days, strain or filter. The dose, as a cathartic, is a tablespoonful to a wineglassful before brealcfast or at night ; as a laxative, a teaspoonful to a dessertspoonful. 3967. Cascara Cordial. Cathartic or Laxative Cordial. This cordial is highly recommended as a remedy for habitual con- stipation and the disorders which attend it, as sick-headache, liver and stomach troubles, etc. Cascara Sagrada Bark, . 16 ounces av. Liquorice Root, 6 ounces av. Sweet Flag Root, . . 2 ounces av. Cardamom Seed, ......... 1 ounce av. Angelica Root, . 1 ounce av. Bicarbonate of Sodium, . ^ ounce av. Diluted Alcohol, 6 pints. Sugar, 2 pounds. Water, sufficient to make 1 gallon. Make in the same manner as is directed for Buckthorn Cordial. Dissolve the Bicarbonate of Sodium in the diluted Alcohol before percolating. The dose, as a cathartic, is a tablespoonful to a wineglassful ; as a laxative, from a teaspoonful to a dessertspoonful. 3968. Castorol. Child's Laxative, " Castoria.'" Under the name "Castoria," a laxative and regulator for children has been extensively sold, and it is an excellent, preparation. The original is made after the formula of Dr. Samuel Pitcher, which is: Senna Leaves, . 16 ounces. Pumpkin Seed, 6 ounces. Anise Seed, 1 ounce. Worm Seed, .... 3 ounces. Rochelle Salts, .4 ounces. Bicarbonate of Sodium, 2 ounces. Sugar, 6^ pounds. Essence of Wintergreen y 2 fl.ounce. Essence of Peppermint, . . 1 fl. drachm Water, sufficient to make 1 gallon. STANDARD PROPRIETARY REMEDIES. 1051 Bruise the Senna, Pumpkin Seeds, Anise, and Worm Seed and steep them in 6 pints of Water, with gentle heat, for three hours ; pour off the liquid and reserve ; put 2 pints more Water on the drugs and steep for one hour more, then pour off the liquid, press lightly, and add the liquid to the portion previously reserved and evaporate it by gentle heat to 5 pints. When cool, strain, add the Essences and dissolve the Sugar, Salts, etc., in the liquid, by agita- tion. This may also be made by water-bath percolation in the usual manner. The dose is half a teaspoonful to a tablespoonful, according to age, etc. It is an excellent laxative for children, and, in fact, for adults. 3969. Cathartic Liver Pills. Extract Nux Vomica, 10 grains. Podophyllin, 10 grains. Capsicum, in fine powder, 20 grains. Extract Hyoscyamus, 30 grains. Purified Aloes, . . .100 grains. Mix and make 100 pills. Each pill contains -fa grain each Extract Nux Vomica and Pod- ophyllin, \ grain of Capsicum, about l /z grain Extract Hyoscyamus, and .1 grain of Purified Aloes. The dose, as a laxative and liver pill, is 1, before meals, from once to three times a day ; as a cathartic, 2 to 4 pills. This is an excellent tonic and liver pill, particularly valuable for habitual constipation, headache, inactive liver, etc., and cannot fail to give satisfaction. 3970. Little Giant Liver Pills. Aloin, 10 grams. Podophyllin, 20 grains. Capsicum, 10 grains. Extract of Xux Vomica, 20 grains. Hyoscyamine, 2 grains. Mix, and make 100 pills. These are generally sold under the title of Little Liver Pills, but are mostly used as a laxative or cathartic, the dose as a cathartic being 3 to 4 pills at night or morning. Many other formulas for Cathartic Pills will be found under "Pills." 1052 STANDARD PROPRIETARY REMEDIES. 3971. Fruit Laxative Lozenges. Under the name Tamar-Indien Tropical Fruit Laxative, Confectio- Laxative, etc., Laxative or Cathartic Lozenges have had a good sale. The following formula makes a good preparation of this sort. They are usually put up half a dozen in a tin box for 25 cents, or one dozen for 50 cents. Tamarind pulp, thick, 2 ounces. Extract of Senna, 2 ounces. Aloin, 10 grains. Podophyllum Resin (Podophyllin), .... 10 grains. Manna, 1 ounce. The Tamarind Pulp should be thick and the Extract of Senna of as firm consistence as can be obtained. The substances should then be warmed and well kneaded together, then rolled out and cut into oval lozenges of about 45 grains, covered with tin foil and wrapped in paraffin paper. The dose, as a laxative, is 1 lozenge at night ; as a light cathartic, 2 lozenges may be taken. Fig Pulp may be used in place of Tamarind Pulp. A very fine lozenge may be made by using a portion of Pistachio paste in the mixture. Grape Sugar may be used in place of Manna, but is not so good. 3972. Laxative Tea. Buckthorn Bark, cut, 4 ounces. Dandelion Root, cut, 4 ounces. Senna Leaves, cut, 4 ounces. Liquorice Root, cut, 1 ounce. Sweet Flag Root, cut, y 2 ounce. Coriander Seed, bruised J /> ounce. Anise Seed, bruised, y 2 ounce. Mix thoroughly, and put up in packages of about two ounces, which will retail for 25 cents. It is prepared in the same manner as No. 113, and the dose, as a cathartic, is about the same. As a laxative, a package may be steeped in a pint of water, strained and mixed with half a pint of whisky or gin and % pound sugar. Dose, a wineglassful. In the form of powder the Compound Powder of Glycyrrhiza (2764) is a good preparation to put up as a general laxative. STANDARD PROPRIETARY REMEDIES. 1053 CHOLERA CURES. The demand for Cholera Cures is limited, of course, to the later summer months, yet there is considerable sale for preparations under this name, as they are used also for dysentery, diarrhoea, etc. Many preparations which may be put up for this purpose have been already given under other headings (see Mixtures, Tinctures, etc.), but the following may be found useful, the first two being original, the others old and popular formulas. Other formulas for similar use will be found under Dysentery Remedies. 3973. Cholera Cure — Stimulating. Capsicum, 4 ounces av. Camphor, 4 ounces av. Catechu, -. 4 ounces av. Opium, 1 ounce av. Oil of Cajeput, 1 fl. ounce. Oil of Peppermint, 1 fi. ounce. Oil of Cinnamon, 2 fi. drachms. Oil of Cloves, 2 fl. drachms. Alcohol, 7>4 pints. Hot Water, 12 fl. ounces. Macerate the Catechu and Opium with the hot Water, rubbing them in a mortar until reduced to a pulpy mass, dissolve the Oils and Camphor in the Alcohol, add the Capsicum and the solution of Catechu and Opium, allowing the mixture to macerate a week or longer, shaking every day, then filter. Dose, as a preventive, 10 to 15 drops in a little water every morn- ing. For cholera, cholera infantum, cholera morbus, colic, cramp, or internal pain, from 15 drops to a teaspoonful in sweetened water every hour, or oftener, if necessary, until relieved. It may also In' applied over the pit of the stomach and bowels. 3974. Cholera Remedy — Sedative. Tincture of Opium 3 rl.ounces. Hydrate of Chloral, i ounce av. Spirit (Essence) of Peppermint i fl. ounce. Ether (Sulphuric), 1 fLounce. Tincture of Catechu, 4 fl. ounces. Diluted Alcohol, 6 fl.ounces. Mix the liquids and dissolve the Hydrate of Chloral in the mixture. Dose and directions the same as the preceding. 1054 STANDARD PROPRIETARY REMEDIES. 3975. Asiatic Tincture for Cholera. Powdered Opium, 1 ounce av. Camphor, 1 ounce av. Oil of Cloves, 1 ounce av. Powdered Capsicum, 1 ounce av. Hoffman's Anodyne, 1 pint. Macerate two weeks and filter. Dose, 20 to 60 drops. 3976. Australian Cholera Specific. Sulphuric Acid, 320 grains. Nitric Acid, 192 grains. Sugar, 240 grains. Gum Arabic, 240 grains. Water, enough to make a pint. Mix the AcichUlifcla 12 fl. ounces of Water, add the Sugar and Gum, dissolve, and add enough Water to make a pint. Dose, a tablespoonful, followed by a drink of water, and repeated in half an hour, or frequently until the disease is checked. The remedy is claimed never to have failed to cure if taken in reasona- ble time. 3977. New-York " Sun " Cholera Mixture. Tincture Capsicum, 1 part. Tincture Opium, 1 part. Tincture Rhubarb, 1 part. Spirit Peppermint, 1 part. Spirit Camphor, 1 part. Mix. Dose, 15 to 30 drops in a wine glass of water. 3978. Russian Cholera Drops. Oil of Peppermint, 75 minims. Tincture Opium, 5 fl. drachms. Wine of Ipecac, 2 fl. ounces. Tincture Valerian, etherial, 4 flounces. Mix. Dose, 10 to 20 minims. STANDARD PROPRIETARY REMEDIES. 1055 3979. Sparkman's Cholera Mixture. Camphor . . 1 drachm. Kino, 2 ounces. Catechu, y 2 ounce. Powdered Cinnamon, 2 ounces. Powdered Cloves, 1 ounce. Powdered Capsicum, 2 ounces. Brandy, q. s. Moisten the powders with Brandy, pack in a percolator, macerate 48 hours and percolate 18 ft. ounces. To this add : Tincture Opium 2^4 fl.ounces. Chloroform, • . 1 fl. ounce. Dose, 60 drops. 3980. Squibb's Cholera Mixture. Chloroform, ... Tincture Opium, Spirit Camphor, Tincture Capsicum, Alcohol, 3 parts. e found convenient for r< : Nicy aiv usually made to answer for most of the general ailments of horses and 1 attle, and are given 1056 STANDARD PROPRIETARY REMEDIES. to increase the appetite, purify the blood, act on the liver, kidneys, etc. The following represent a variety and serve as sample formulas : 3982. Condition Powder — Vegetable. For the Blood and Appetite. Bloodroot, in fine powder, 1 ounce. Sassafras, in fine powder, 3 ounces. Liquorice Root, in fine powder, 3 ounces. Gentian, in fine powder, 1 ounce. Ginger, in fine powder, 2 ounces. Fenugreek Seed, in fine powder, 4 ounces. Senna, in fine powder, 2 ounces. Mix. Dose, a tablespoonful or more in feed. It will be observed that this powder is entirely vegetable and more expensive than many of the others. It may be made cheaper by adding to it an equal bulk of Linseed Meal. 3983. Condition Powder— Mineral. Blood Purifier and Tonic. Nitrate of Potassium (Saltpetre), 2 ounces. Bitartrate of Potassium (Cream Tartar), ... 3 ounces. Sulphate of Iron (Copperas), 2 ounces. Sulphate of Antimony (Black Antimony), . . 1 ounce. Sulphur, 8 ounces. Powder and mix. Dose, a tablespoonful or more in feed, 3984. Condition Powder — Diuretic. Appetizer, Tonic, Diuretic, Etc. Gentian, in fine powder, 1 ounce. Ginger, in fine powder, 2 ounces. Fenugreek Seed, in fine powder, 4 ounces. Black Antimony, in fine powder, 1 ounce. Liquorice Root, in fine powder, 3 ounces. Sal. Nitre, in fine powder, 2 ounces. Linseed Meal, in fine powder, 3 ounces. Mix. Dose, a tablespoonful or more in feed. STANDARD PROPRIETARY REMEDIES. 1057 3985- Condition Powder — General. Gentian, in powder, 1 ounce. Fenugreek Seed, in powder, 4 ounces. Ginger, in powder, 2 ounces. Liquorice Root, in powder, 3 ounces. Resin, in powder, 3 ounces. Sulphur, in powder, 3 ounces. Mix. Dose, a tablespoonful or more in feed. 3986. Condition Powder — General. Sal. Nitre, in powder, , . . . 1 ounce. Ginger, in powder, 2 ounces. Fenugreek, in powder, 3 ounces. Black Antimony, in powder, 1 ounce. Liquorice Root, in powder, 1 ounce. Linseed Meal, in powder, 8 ounces. Mix. Dose, a tablespoonful or more in feed. 3987. Heave Powder. For Coughs, Colds, Heaves, Etc. Lobelia, in fine powder, 2 ounces. Skunk Cabbage, in fine powder, 4 ounces. Elecampane, in fine powder, 4 ounces. Tartrate of Antimony and Potassium, . . . 1 ounce. Liquorice Root, in fine powder, 5 ounces. Mix them. The dose is a dessertspoonful to a tablespoonful in feed. This may be diluted, if desired, with Linseed Meal, powdered Fenugreek, or other powdered drugs. 3988. Hog Cholera Powder. Remedies for the prevention and cure of Hog Cholera are much used in the West and South. They are of various composition and merits. The following, which is similar to Haas' Hog Remedy, is as popular as any : Phosphate of Lime, precipitated, .... 8 ounces. Common Chalk, in powder, 6 ounces. Carbonate of Magnesium, powdered, ... 2 ounces. Capsicum, powdered )' z ounce. Mix them well together. 1058 STANDARD PROPRIETARY REMEDIES. 3989. Hog Cholera Cure. The following is similar to another popular powder : Bicarbonate of Sodium 2 ounces. Powdered Gentian, 2 ounces. Powdered Ginger, 3 ounces. Powdered Nitre, 1 ounce. Powdered Chalk, 8 ounces. Mix them thoroughly. The doses of these powders are, as a preventive, from 1 to 2 tea- spoonfuls in feed twice a clay ; as a cure, a tablespoonful 3 or 4 times a day. 3990. Poultry Powder. For the diseases incident to poultry a general powder may be pre- pared as follows : Bone, ground, or Slaked Lime, 12 ounces. Gentian, powdered, 1 ounce. Capsicum, powdered, 1 ounce. Ginger, powdered, 2 ounces. Sulphur, 1 ounce. Mix them well together. Put a teaspoonful in a quart of feed. 3991- £ g£ Food. Phosphate of Lime or Ground Bone, . . . .12 ounces. Capsicum, in powder, 1 ounce. Ginger, in powder, 2 ounces. Cantharides, in powder, 1 drachm. Sulphur, 1 ounce. Nitrate of Potassium, powdered, 1 ounce. Mix them well. Put a tablespoonful in a quart of feed. 3992. Worm Powder. For Worms and Botts in Horses and Cattle. Cape Aloes, in powder, 5 ounces. Betel or Areca Nut, in powder, 8 ounces. Anise, in powder, 1 ounce. Fenugreek Seed, in powder, 2 ounces. Mix them well together. Dose, 2 tablespoonfuls in feed, morning and night. STANDARD PROPRIETARY REMEDIES. 1059 CORN, BUNION, AND CHILBLAIN CURES. For the past few years Corn Cures have been the rage, and have become almost as plenty, but not quite so painful, as the corns themselves. The most popular remedies have been those in which Collodion has been used as a base, and which form an artificial skin when applied, and thus keep the medicinal agents in place. The same remedies also apply to bunions. Chilblains require other treatment, but are included under this heading. 3993. Corn Killer. This preparation is similar to a variety of preparations known as Gerfnan Corn Cures, Corn Eradicators, and by many other names. Extract of Cannabis Indica is used in some, giving the preparation a greenish color. Gun Cotton (Pyroxylin), 200 grains. Ether (Sulphuric), i£}4 flounces. Alcohol, 2>Yz A. ounces. Salicylic Acid, 2 ounces av. Chloride of Zinc, 1 ounce av. Mix the Ether and Alcohol and dissolve the Gun Cotton in the mixture (this will require a day or two), then add the Salicylic Acid and, when it has dissolved, add the Chloride of Zinc. Keep tightly stopped and away from the light or fire. This is applied once a day for three days in succession, the part is then bathed in warm water and the skin and adhering corn removed. It may also be applied to bunions. 3994. Corn Salve — Caustic. A number of Corn Salves have been popular proprietary prepar- ations, but are not generally so effective as the foregoing. Caustic Soda or Potassa, 4 ounces av. Water, 4 fl. ounces. Starch, in fine powder, i ounce av. Glycerin, 8 ounces av. Dissolve the Soda or Potassa in the Water by the aid of heat, mix the Starch with the Glycerin and heat, with constant stirring, until the Stanh is entirely gelatinized and the preparation is of a uniform consistence, then mix with it the warm solution of Soda and put up while warm in small, wide-mouth bottles or glass boxes. 1060 STANDARD PROPRIETARY REMEDIES. To use, spread a little of the salve on the corn or bunion, taking care to cover only the part to be removed, cover with a piece of cloth and allow to remain from two to four hours, then soak the parts in warm water. This is a caustic application and needs only to be applied once or twice. It is equally efficacious for warts. 3995. Corn Salve — Magic. Salicylic Acid, 2 drachms. Arsenic, 1 drachm. Petrolatum, 1 ounce. Mix them by rubbing well together to form a salve which may be applied on a piece of linen. 3996. Corn Plaster. The most familiar Corn Plasters are those made by spreading some adhesive plaster over thick felt and then cutting, leaving a hole in the centre, allowing the corn to stick up and thus relieving the pressure upon it. A good Corn Plaster, to be spread upon leather or cloth, and thus applied to the corn, may be made with Salicylic Acid 1 part, Burgundy Pitch 1 part, Yellow Wax 1 part, melted together and mixed. 3997. Chilblain Lotion. Oil of Eucalyptus, 2 fi. ounces. Camphor, 2 ounces av. Carbolic Acid, 1 ounce av. Alcohol, sufficient to make 1 pint. Mix and dissolve. To be applied night and morning. It reduces the inflammation and is a sure cure for chilblains before they break. 3998. Chilblain Ointment. Oil of Eucalyptus, 1 fl. ounce. Camphor, 1 . ounce av. Carbolic Acid, ^ ounce av. Yellow Wax, 2 ounces av. Petrolatum, 12 ounces av. Mix the Wax and Petrolatum and, having mixed the other ingre- dients and dissolved them, add to the melted substances while cool- ing and mix well. This is a soothing and curative ointment for chilblains and tender feet. STANDARD PROPRIETARY REMEDIES. 1061 COUGH REMEDIES. The variety of cough preparations sold as proprietary remedies is greater than any other line of " patent medicines," and their sale altogether is probably as large as any, but being distributed among so many different kinds is not so noticeable as of some other lines of remedies. In the formulas which follow we have selected repre- sentatives only of such as are most popular. They are known on the market by names similar to those given, but the formulas do not claim to make exact duplicates of manufacturer's proprietary medi- cines, only that they are as good as any. As a general cough rem- edy the first one of the series (Xo. 3999) is recommended as giving good satisfaction. It is not like any other in the market, but will make a fine preparation. 3999. Cough Remedy. Paregoric, .8 fi. ounces. Fluid Extract Ipecac, 1 fl. ounce. Fluid Extract Squill, 1 fl. ounce. Tincture Tolu 2 fl.ounces. Tincture Lobelia, 1 fl. ounce. Tincture Hyoscya'mus, ....... 2 fl.ounces. Powdered Extract of Liquorice, .... ^ ounce av. Tartar Emetic, 50 grains. Muriate of Ammonia, 2 ounces av. Chloroform, }j ounce a v. Carbonate of Magnesium Yt. ounce av. Sugar, 5 pounds av. Water, sufficient to make a gallon. Rub the Tincture of Tolu with the Carbonate of Magnesium in a mortar, mix the Tinctures and Fluid Extracts with hall' a gallon of Water, dissolve the Extract of Liquorice in the mixture, add it to the Magnesia, etc., in the mortar and filter through paper until dear. Dissolve the Tartar Emetic in 4 ounces of boiling Water and add the solution and the Muriate of Ammonia to the filtrate and di»olve, put the Sugar in a gallon bottle or jug, add the Chloro- form to the dry'Sugar and mix them thoroughly, then add the liquid previously prepared and enough Water to make a gallon, and dissolve the Sugar by agitation. This is an excellent general cough remedy, the dose being 'i t" 1 teaspoonful. 1062 STANDARD PROPRIETARY REMEDIES. 4000. Cough Balsam. Tincture of Tolu, y? fl. ounce. Tincture of Opium, ^2 fl. ounce. Tincture of Bloodroot, . x /i fl. ounce. Fluid Extract of Conium, ]/?. fl. ounce. Fluid Extract of Elecampane, ^ fl. ounce. Oil of Sassafras, 5 drops. Tartar Emetic, 8 grains. Boiling Water, 1 fl. ounce. New Orleans Molasses, ....... 14 fl. ounces. Dissolve the Tartar Emetic in the boiling Water and add it to the Molasses, dissolve the Oil of Sassafras in the Tincture of Tolu, mix it with the other tinctures and fluid extracts, and add the Molasses to the mixture, shaking them thoroughly together. 4001. Cough Cordial. Anise Seed, Y /z ounce av. Fennel Seed, 20 grains. Blood Root, 180 grains. Wild Cherry 1 ounce av. Liquorice Root, J4 ounce av. Alcohol, ■ 6 fl. ounces. Water, q. s., or 10 fl. ounces. Sugar, 6 ounces av. Grind the drugs to a coarse powder, mix the Alcohol with 8 ounces of Water and, having moistened the drug with 4 ounces of the mixture, allow them to macerate in a covered vessel for 24 hours ; then pack moderately in a percolator, pour upon them the remainder of the liquid and percolate, adding Water through the percolator after the liquid has disappeared from the surface, and continuing the percolation until 13 fl.ounces have passed. In this dissolve the Sugar and, after standing a few days, filter. 4002. Cough Cure. Syrup of Squill, 3 fl.ounces. . Syrup of Tolu, 6 fl.ounces. Wine of Ipecac, 3 fl.ounces. Hydrocyanic Acid, diluted, 2 fl drachms. Tincture of Opium, Camphorated, ... 3 fl.ounces. Tincture of Sanguinaria, y 2 fl.ounce. Mix them. This is an excellent sedative cough cure. STANDARD PROPRIETARY REMEDIES. 1063 4003. Cough Honey. Sulphate of Morphine, ....... S grains. Tartar Emetic, . . 8 grains. Muriate of Ammonia, . . ... 256 grains. Boiling Water, . . 1 fl. ounce. Tincture of Opium, Camphorated, . . 1 fl. ounce. Tincture of Tolu, ... ... ) z fl. ounce. Sugar, . . .... 14 ounces av. Water, . ....... 7 fl. ounces. Mix the Tinctures with the Sugar and agitate in a bottle, dissolve the Morphine and Tartar Emetic in the boiling Water, and the Muriate of Ammonia in 6 ounces of cold Water ; mix the solutions and add them to the Sugar in the bottle. Dissolve by agitation. If a clear preparation is desired, the Tolu may be rubbed with Magnesium Carbonate and Water, and filtered. 4004. Consumption Cure. Tincture of Tolu, Fluid Extract of Lobelia, Fluid Extract of Indian Cannabis, Sulphate of Morphine, 8 Tartar Emetic Chloroform, Essence of Peppermint, Boiling Water, Sugar, Water, Mix the Fluid Extracts, Tincture of Tolu, Chloroform, and Essence with the Sugar in a bottle, and agitate them thoroughly ; dissolve the Morphine and Tartar Emetic in the boiling Water, and add the solution with the 8 ounce- oi Water to the Sugar in the bottle ; keep tightly stopped and agitate until the Sugar is dissolved. This makes a preparation quite similar to Piso's Cure. As thus prepared this preparation is not dear, but translucent. A clear syrup may be made by rubbing the tincture of Tolu, Fluid Extract of Lobelia, Fluid Extract of Cannabis [ndica and Essem e ol Peppermint first with '.- ounce of Carbonate of Magnesium, then adding in the mortar 8 0Un< es of water, nil. bin-' them well together, filtering, adding the Tarter Emetic dissolved in the boiling water, mixing the chloroform with the sugar, and then dissolving the Sugar and morphine in the liquid. '_> fl. ounce. ! 4 fl. ounce. '4 fl. ounce. 8 grams. 8 grains. 1 tl. drachm. '5 drops. 1 tl. ounce. M ounces av. s tl. ounces L064 STANDARD PROPRIETARY REMEDIES. 4005. Cure- for Consumption. Oil of Wintergreen, 5 minims. Oil of Peppermint, 15 minims. Oil of Tar, 60 minims. Tincture of Tolu, y 2 fl. ounce. Tincture of Sanguinaria, y 2 flounce. Fluid Extract of Ipecac, % fl.ounce. Hydrocyanic Acid, % fl.ounce. Chloroform r 40 grains. Molasses (Porto Rico) 1 pint. Mix and agitate thoroughly. This is similar to a Western preparation. 4006. Compound. Syrup of Tar and Wild Cherry. " German Syrup." Oil of Tar, 1 fl. drachm. Fluid Extract of Ipecac, ^2 fl.ounce. Fluid Extract of Wild Cherry, . . . . 1 fl.ounce. Tincture of Opium, y 2 fl.ounce. Sugar, 14 ounces av. Water, 8 fl. ounces. Mix the Oil of Tar by Trituration with the Sugar, add the Fluid Extracts and Tincture to the Water and filter, then dissolve the Sugar, by agitation in the filtrate. This may also be made by adding 1 fl. drachm of Oil of Tar and 1 fl.ounce of Fluid Extract of Wild Cherry to many of the Cough Remedies previously noticed, afterward straining or filtering if necessary. 4007. Compound Syrup of White Pine. To make this Syrup it is first necessary to prepare a Tincture of White Pine, which is made as follows : TINCTURE OF WHITE PINE. White Pine Turpentine (Gum Thus.), . . 2 ounces av. Alcohol, 14 fl. ounces. Cut the gum in small pieces and dissolve it in the Alcohol by the aid of a water-bath, or by macerating for two weeks in a warm place. STANDARD PROPRIETARY REMEDIES. 1065 COMPOUND SYRUP WHITE PINE. Sulphate of Morphine, 8 grains. Fluid Extract of Ipecac y 2 flounce. Chloroform, i fl. drachm. Tincture White Pine, 2 ft.ounces. Carbonate of Magnesium y 2 ounce av. Water, 8 fl. ounces. Sugar, 14 ounces av. Rub the Carbonate of Magnesium with 1 ounce of Sugar to a fine powder in a mortar and add to it the Tincture of White Pine, rubbing them thoroughly together, then add the Fluid Extract, gradually rub the Water with the mixture and filter ; mix the Chloroform with the Sugar in a bottle, dissolve the Morphine in the liquid, then mix the liquid with the Sugar in the bottle ami dissolve by agitation. 4008. Compound Syrup of Wild Cherry. Wild Cherry, in coarse powder, .... 2 ounces av. Ipecac, in fine powder, }4 ounce av. Bloodroot, in fine powder, j£ ounce av. Tincture of Opium, Yz fl.ounce. Water, q. s., or 12 fl. ounces. Sugar, • 14 ounces av. Chloroform, 1 fl. drachm. Mix the drugs, moisten them with 4 ounces of Water, and macer- ate for 12 hours, then pack moderately in a conical percolator and percolate with Water until 9 fl. ounces are obtained ; mix the Chloro- form with the Sugar in a bottle, add the percolate and dissolve by agitation. 4009. Cough Mixture. The following, with various modifications and additions, is a very common and popular prescription for coughs, etc.: Syrup of Squill, i ounce. Syrup of Tolu, . . .' 1 ounce. Wine of [pecac i ounce. Tincture of Opium, Camphorated, i ounce. To this is frequently added : Tincture of Bloodroot, ! { ouni e. Syrup of Wild < Iherry i ounce. Hydrocyanic Acid, diluted bounce. And various other medicines. 1066 STANDARD PROPRIETARY REMEDIES. 4010. Expectorant. Fluid Extract of Hyoscyamus. ..... y? fi. ounce. Fluid Extract of Lobelia, %. flounce. Fluid Extract of Skunk Cabbage, .... ^ fl. ounce. Cyanide of Potassium, 8 grains. Water, y^ fl. ounce. New Orleans Molasses, 14 fl. ounces. Dissolve the Cyanide of Potassium in the Water and mix with the Syrup, then add the Fluid Extracts and mix thoroughly. 4011. Honey of Hoarhound and Tar. Powdered Opium, 60 grains. Hoarhound, ^2 ounce av. Wild Cherry, 2 ounces av. Ipecac, Yo ounce av. Pine Tar, y 2 ounce av. Water, q. s., or 12 fl. ounces. Sugar, 14 ounces av. Grind the drugs to a coarse powder and mix them thoroughly with the Tar, pour upon them 4 ounces of Water and macerate for 24 hours, then pack moderately in a conical percolator and perco- late with Water until 9 ounces are obtained ; dissolve in this the Sugar by agitation. 4012. Sedative Cough Remedy. Without Opium. This formula is given to furnish a good remedy without opium (which is often objectionable). This preparation is especially valu- able in irritating and obstinate coughs and is a pleasant sedative and expectorant cough remedy. Bromide of Potassium, 1 ounce av. Tincture of Sanguinaria (Bloodroot), . . 3 fl. drachms. Tincture of Hyoscyamus, 2 fl.ounces. Ether (Sulphuric), >^ fl. ounce.- Syrup of Ipecac, 2 fl.ounces. Syrup of Tolu, 7 fl.ounces. Alcohol, 1 fl. ounce. Water, 3 fl.ounces. STANDARD PROPRIETARY REMEDIES. 1067 Dissolve the Bromide of Potassium in the Water and mix the solution with the Syrups ; mix the Alcohol with the Ether and Tinc- tures, then add the mixture to the Syrups and mix. Dose, the same as other cough remedies, but may be given freely without injury. 4013. Lung Balsam. Xitric Acid, . . 120 minims. Fluid Extract af Lobelia, . . .1 fl.ounce. Tincture of Opium, . . .... 6 fl. ounces. Fluid Extract of Conium, 4 fl. ounces. Extract of Liquorice, ... . • • 3 ounces av. Oil of Sassafras, . . 10 minims. Alcohol, ... 1 pint. Boiling Water, . . . . . . 8 fl. ounces. Water, 2 pints. Porto Rico Molasses, . . 4 pints. Mix the Fluid Extracts, Tincture of Opium, Oil, Acid, and Extract of Liquorice with the Water and Alcohol ; dissolve the Tartar Emetic in the boiling Water and add to the mixture, filter and add the Molasses to the filtrate. The dose is a teaSpoonful. 4014. Terebene Cough Mixture. Terebene, purified 1 fl.ounce. Acacia, in powder '_■ ounce av. Sugar, .... 3 ounces av. Yolk of Egg, No. 2. Anise Water, 2 tl. ounces. Camphor Water, }4 fl.oum e. Distilled Water, to make S ll. ounces. Rub the Acacia and Sugar with the Terebene in a mortar, beat the Volk of Egg with the medicated Waters and make an emulsion by rubbing with the contents of the mortar, then add Water enough to make 8 fl.OUnces. By using Lemon Juice instead Of the distilled Water a more palatable preparation may be made. The dose is a teaspoonful. 4015. Cough Drops or Candy. There are in the market a great variety of "Cough Drops," which are mainly sold by the ounce and not put up in the general style of proprietary remedies. They are usually made by COnfeC- 1068 STANDARD PROPRIETARY REMEDIES. doners and moulded in various shapes, and colored either black, red, or brown. The most popular Black Cough Drops were intro- duced by Smith Brothers, of Poughkeepsie, N. Y. A similar prep- aration may be made by adding to i pound of Rock Candy and i pound of Sugar, mixed and boiled to the proper consistence for making drops, 2 ounces Tincture of Opium, 20 grains Tartar Emetic, % ounce Oil of Anise, % ounce Oil of Wintergreen, and coloring black with Negrosine. Cherry Cough Drops are made by adding to 3 parts of Rock Candy and 1 part of Sugar, mixed and boiled to the proper consistence, a very little morphine, tartar emetic, capsicum, and flavoring with bitter almond, and coloring red. 4016. Cough Lozenges or Troches. Many kinds of Cough Troches or Lozenges have been popular as proprietary medicines. Brown's Bronchial Troches have been as well received as any, but now the compound troches, tablets, or loz- enges for colds are coming more into use. A good Bronchial Troche, similar to the most popular ones, may be made as follows : Extract of Liquorice, in powder, . . . * 1 pound. Cubebs, in fine powder, 6 ounces. Sugar, in fine powder, i^4 pound. Acacia, in fine powder, 4 ounces. Extract of Conium, powdered, 1 ounce. Tartar Emetic, in powder, 1 drachm. Mix them well together and, with Mucilage or Water, make into a mass, which is to be rolled out and cut into Lozenges of about 10 grains. By adding other substances, as Morphine, Opium, Ipecac, etc., other varieties may be made. Similar ingredients may be made into compressed Lozenges, if desired. DIARRHCEA AND DYSENTERY REMEDIES. The milder forms of remedies which are used for summer com- plaints and looseness of the bowels are known in proprietary medi- cines as Diarrhoea or Dysentery Remedies. Carminatives, which have been already mentioned, are similar. The stronger prepara- STANDARD PROPRIETARY REMEDIES. 1069 tions are mostly known as cholera cures, mixtures, drops, or by some other similar title. See Cholera Cures, page 1053. The following are the most popular : 4017. Blackberry Cordial. Blackberry Juice, 4 pints. Catechu, 4 ounces av. Cinnamon, 1 ounce. Nutmeg, 1 ounce. Coriander Seed 1 ounce. Opium, in powder % ounce. Sugar, 2 pounds av. Alcohol, 2^2 pints. Water, sufficient to make 1 gallon. Grind the drugs to a coarse powder and, having mixed the Black- berry Juice with the Alcohol, macerate them for a week or ten days in a warm place, then filter, add the Sugar, dissolve by agitation, and, having passed enough Water through the filter, add it to the mixture to make 1 gallon of the finished product. Dose from a teaspoonful to a dessertspoonful every hour or two until diarrhoea is checked. This makes a finely flavored, pleasant, and efficient cordial for summer complaints, and will give universal satisfaction. It may be made from the juice freshly expressed from the berries, or from well preserved Blackberry Juice put up by reliable houses. The following formula, although not quite so nicely flavored, is just as efficient and more convenient to make at all seasons of the year. 4018. Blackberry Cordial. Made from the Root. Blackberry Root 24 ounces av. Nutmeg, 1 ounce a\ . Cinnamon, 1 ounce av. Coriander Seed, i ounce av. Opium, in powder, % ounce av. Sugar, 12 ounces av. Alcohol, -''.■ pints. Water, sufficient to make i gallon, Grind the drugs to a moderately fine powder and, having mixed the Alcohol with 5 pints of Water, moisten them with 2 pints of the 1070 STANDARD PROPRIETARY REMEDIES. mixture and macerate for 24 hours in a covered vessel, then transfer to the water-bath percolator, pack moderately, pour upon them the remainder of the menstruum, heat moderately for one hour, then turn off the heat and begin to percolate, adding Water to the drugs after the liquid has disappeared from the top and continuing the percola- tion until 7^2 pints have been obtained. Lastly, dissolve the Sugar in the percolate and filter. Many other remedies for diarrhoea, dysentery and summer com- plaints will be found under other headings. 4019. Diarrhoea Tablets. Catechu in powder, 200 grains. Kino in powder, 100 grains. Opium in powder, 25 grains. Sugar in powder, 600 grains. Gum Arabic in powder 175 grains. Oil of Cinnamon, 20 drops. Mucilage Acacia, to make a mass which is to be made into 100 lozenges. Dose 1 to 4. DYSPEPSIA CURES. Among the general remedies for Dyspepsia may be included all the tonic, stomach, iron, and blood bitters, the alterative tonics and stimulants ; but besides these are a class of remedies particularly designed for Dyspepsia, which have a large sale. Dyspepsia is the chief cause of indigestion of amylaceous and nitrogenous food, and it is rational to supply to the stomach the lacking ferments or sol- vents of those foods, that it may perform its proper functions. Diastase is the proper solvent for amylaceous food and pepsin for nitrogenous. In the animal economy diastase is a constituent of saliva, and in the vegetable it is found in greatest abundance in malted grain, being now most employed in medicine in the form of Malt Extract. Pepsin is the digestive ferment of the stomach, and is abundantly obtained from the stomachs of various animals. Now, while it would seem reasonable to supply to a dyspeptic stom- ach these elements, the absence of which causes indigestion, yet there are few dyspepsia cures on the market that do so, and, as we STANDARD PROPRIETARY REMEDIES. 1071 must "follow the fashion," and make formulas for remedfes like some that are popular, we give a little variety. 4020. Dyspepsia Remedy. A proprietary remedy known as " August Flower" similar to the following, has had a large sale in this country : Rhubarb, 6 ounces av. Golden Seal, i)4 ounce av. Cape Aloes, % ounce av. Peppermint, herb, freshly dried, .... 2 ounces av. Carbonate of Potassium (Sal. Tartar), . 2 ounces av. Capsicum, 30 grains. Spirit (Essence) of Peppermint, .... 3 fl. drachms. Alcohol, 24 flounces. Porto Rico Molasses, 2 pints. Water, sufficient to make a gallon. Reduce the drugs to a coarse powder and, having mixed the Alco- hol with 3 pints of Water, dissolve the Carbonate of Potassium in the mixture, moisten the powder with 12 ounces of the liquid and macerate in a warm place for 24 hours ; transfer to a percolator, pack very moderately, pour upon it the remainder of the liquid and percolate, adding Water to the drugs after the liquid has disap- peared from the surface, and continuing the percolation until 6 pints have passed ; to this add the Essence of Peppermint and Molasses and, after standing a few days, strain or decant. This may also be made advantageously by water-bath percolation. The dose is a teaspoonful to a tablespoonful after meals. 4021. Dyspepsia Tonic. Tincture of Gentian Compound, .... 4 fl. ounces. Tincture of Rhubarb 4 fl. ounces. Tincture of dinger . . i fl.ounce. Essence of Peppermint yd fl.ounce. Bicarbonate of Sodium ^ ounce av. Water, sufficient to make a pint. Mix the Tinctures, etc., dissolve the Bicarbonate of Sodium in the Water, mix the solutions ami, after standing a day or two. filter. This is an excellent general remedy I'm' atonic dyspepsia with acid stomach, llatulcne.e, etc. Do e, a teaspoonful to a dessertspoonful after meals. 1072 STANDARD PROPRIETARY REMEDIES. 4022. Digestive Dyspepsia Remedy. Malt Extract, 6 fl. ounces. Pepsin, saccharated, ......... 240 grains. Tincture of Ginger, - 1 fl. ounce. Fluid Extract of Golden Seal, .... 1 fl. ounce. Essence of Peppermint y 2 fl. ounce. Fluid Extract of Senna 1 fl.ou.nce. Whisky, 4 flounces. Water, enough to make a pint. Mix them. " Shake before taking." Dose, teaspoonful or more after meals. This is not a nice-looking mixture, and would hardly be a popular remedy for the market. It is also too expensive for general sale, but it is a very effective digestive and dyspepsia remedy, and may be found useful by some of our readers. 4023. Dyspepsia Tablets. Saccharated Pepsin, 1000 grains. Saccharated Pancreatin, 1000 grains. Ginger, in fine powder, ........ 50 grains. Oil of Pimento, 50 minims. Acacia, in powder, . . 300 grains. Make into a mass with water or mucilage and divide into 100 tablets. Peptonic Tablets may be made to contain in each, pure Pepsin, 1 grain, pure Pancreatin, 1 grain, with Sugar and Gum to make a 5 grain compressed tablet. Soda-Mint Tablets are made 5 grains of Bicarbonate of Sodium and Yt, minim Oil of Peppermint in each. 4024. Dyspepsia Lozenges. A less expensive Dyspepsia Lozenge or Tablet may be made^with Rhubarb, in fine powder, 500 grains. Subnitrate of Bismuth, 500 grains. Bicarbonate of Sodium, 300 grains. Ginger, in fine powder, 100 grains. Oil of Peppermint, 50 minims. Acacia, in fine powder, 300 grains. Sugar, in fine powder, 300 grains. Make into a mass with mucilage and divide into 100 tablets or lozenges. STANDARD PROPRIETARY REMEDIES. 1073 ELIXIRS, ESSENCES, AND EXTRACTS. Quite a variety of proprietary preparations, under the name Elixirs, Essences, and Extracts, are found in the market, but most of them are included in this work under other headings. Of the first, the general Elixirs of Calisaya, Calisaya and Iron, and their combinations, Gentian and Tincture of Chloride of Iron, Elixirs of Pepsin, Elixirs of Lactopeptine, and combinations, have been very popular as pseudo-proprietary medicines. Many other proprietary medicines are also known as Elixirs, as Blood Elixir, Tonic Elixir, Down's Elixir for Coughs, McMunn's Elixir of Opium, etc. Of the proprietary remedies known as Essences, Essence of (rin- ger is the only one which has any popular sale, and that is more frequently called for as Extract of Ginger than as it is usually labeled. Of the Extracts sold as proprietary most of them are included under other headings, but a few are mentioned here for want of better classification. 4024. Essence or Extract of Jamaica Ginger. This preparation, more than any other, has been a popular favorite for mild forms of Diarrhoea and Summer Complaint. It is also much used as a quick stimulant for colds, cramp, colic, etc., and for dyspepsia. It is a popular domestic remedy and has a ready sale at all drug stores. The formula is as follows : Jamaica Ginger Root, unbleached, in mod- erately fine powder, 3 pounds av. Alcohol, sufficient to make 1 gallon. .Moisten the powder with 2 pints of Alcohol and pack firmly in the water-bath percolator, pour upon it 2 pints of Alcohol and set in a warm place for two days, then heat moderately and, after one hour, begin to percolate, adding Alcohol to the drug and continu- ing the heat and percolation until i gallon is obtained. The Alco- hol remaining in the drug may be recovered by distillation. The process of water-bath percolation is particularly valuable in making this preparation ; no extract can be made by the cold pro- cess which equals it in flavor and strength. Consequently, many manufacturers have been in the habit of adding ( apsicum, which is very objectionable in such a preparation. The dose of this preparation is from 10 to 60 drops in sweetened water. K»?4 STANDARD PROPRIETARY REMEDIES. 4025. Aromatic Extract of Jamaica Ginger. As some of the Essences of Ginger on the market contain aromatics combined with the Ginger, this formula is given : Jamaica Ginger, unbleached, in powder, . . 3 pounds av. Calamus, in powder, 1 ounce. Canada Snake Root, in powder, . , . . 1 ounce. Cinnamon and Mace, each, 1 drachm. Oil of Lemon, fresh 2 fi. drachms. Alcohol, sufficient to make . . . . . 1 gallon. Make an extract of the drugs by percolation the same as directed in the preceding formula and add the .Oil of Lemon. This is used for the same purposes and given in the same quanti- ties as the preceding. 4026. Extract Pinus Canadensis. This is a fluid extract prepared from the inner bark of hemlock trees, by extracting with water and evaporating the liquor until it is reduced to a thick fluid extract, which may be preserved by the addition of 3 fl. ounces of glycerin in a pint. A " white " or colorless extract is made from this by mixing with freshly precipitated Oxide of Iron and treating as directed for detan- nating(5i5). These Extracts are used for washes, injections, etc., and given internally for chronic diarrhoea and other similar diseases. 4027. Extract of Shaker's Roots. Sarsaparilla Root, 4 ounces. Leptandra Root, 2 ounces. Mandrake Root, 1 ounce. Valerian Root, 2 ounces. Calamus Root, 1 ounce. Hydrangea Root, 4 ounces. Diluted Alcohol, sufficient to make . . . . 1 pint. Make a pint of Extract by water-bath percolation. This is a general alterative, given in small doses, for almost everything. Other Extracts, which are put up as proprietary, are mostly included under other headings. The Buchu Extracts will be found under Kidney and Liver Cures, the Malt Extracts and combinations under Malt preparations, Witch Hazel Extract under Distilled Extracts, the Sarsaparilla Extracts under various headings, etc. STANDARD PROPRIETARY REMEDIES. 1075 EYE WATERS. Although the sale for proprietary Eye Waters is small as com- pared with other remedies it is steady, and the preparations pay a large margin of profit and are easily prepared ; therefore druggists can make it profitable to put them up. The following formulas are representative of the best prepara- tions of this kind : 4028. Standard Eye Water. Sulphate of Zinc, 20 grains. Sulphate of Morphine, 16 grains. Glycerin, 2 fl ounces. Rose Water, 14 tl. ounces. Mix and dissolve. 4029. Eye Water. Fluid Hydrastis, 2 fl. drachms. Sulphate of Zinc, 16 grains. Sulphate of -Morphine, .16 grains. Borax 30 grains. Glycerin 2 fl. ounces. Rose Water 14 fl. ounces. Mix and dissolve. 4030. Eye Water. Solution Subacetate of Lead, ^o minims. ( rlycerin, 2 il. ounces. Distilled Water 14 fl.OUnces. Mix. Any of the foregoing formulae make good general Eye Waters, similar to those which are sold as proprietary remedies. They are usually put up in i oun< e bottles and sold at 25 cents. EYE SALVES. The demand for Eye Salves, like Eye Waters, is steady but not large, yet they are so easily made and so profitable thai druggists hould put them up for their trade. The following formulae make 1076 STANDARD PROPRIETARY REMEDIES. reliable preparations. It is necessary to have all the ingredients in very fine powder, and have them thoroughly mixed : 4031. Standard Eye Salve. Oxide of Zinc, 1 ounce. Sulphate of Morphine, 30 grains. White Petrolatum Ointment, 9 ounces. Rub the Morphine intimately with the Zinc to an impalpable powder and gradually incorporate the Petrolatum with the mixture. The Hubbuck's English Oxide of Zinc is the best for this purpose. 4032. Astringent Eye Salve. Liquor of Subacetate of Lead, 2 fl. drachms. Opium, in fine powder, 30 grains. Tannin, in fine powder, 20 grains. White Petrolatum Ointment, 8 ounces. Mix the Goulard's Extract (Liquor Subacetate of Lead) with the Tannin and Opium and gradually incorporate the Petrolatum Oint- ment with the mixture. This is particularly useful for granulated lids and chronic sore eyes. 4033. Eye Salve. Ammoniated Mercury (White Precipitate), . . 240 grains. Sulphate of Morphine, 20 grains. White Petrolatum Ointment, 8 ounces. Rub the Ammoniated Mercury and the Morphine to a very fine powder and gradually incorporate the Ointment intimately with the mixture. 4034. Eye Salve. Calamine, 1 ounce. Sulphate of Morphine, 20 grains. White Petrolatum Ointment, 9 ounces. Rub the Calamine and Morphine together and gradually incor- porate the Ointment with the mixture. FEMALE REMEDIES. For the past few years a very large trade has been built up on proprietary remedies for female complaints. These consist mostly STANDARD PROPRIETARY REMEDIES. 1077 of uterine and nerve tonics combined. The following formulae will make preparations as valuable and reliable as any, and are repre- sentative of different kinds. 4035. Female Remedy. Women's Health Restorative. Cramp Bark [Vtb urn inn Opulus), ... 8 ounces av. Catnep, 4 ounces av. False Unicorn Root (Helonlas), .... 8 ounces av. Senna Leaves, S ounces av. Partridgeberry (Mitehella), 12 ounces av. Cinnamon "Saigon," ....... % ounce. Nutmeg, Yi ounce. Spirit of Nitrous Ether, 4 fl. ounces. Sugar, 8 ounces av. Alcohol, • • 3 pints. Water, sufficient to make a gallon. Grind the drugs to a coarse powder and, having mixed the Alco- hol with 3 pints of Water, moisten the powder with 3 pints of the liquid, pack firmly in the water-bath percolator, pour upon it the remainder of the liquid and set in a warm place for two days, then heat moderately and, after one hour, begin to percolate, adding Water to the drug after the liquid has all disappeared from the surface of the drugs, and continuing the percolation with Water until 7 'j pints have been obtained ; to this add the Sugar and Spirit of Nitre; dissolve and filter. This may be made from the fluid extracts, instead of the drugs, as follows : Fluid Extract Cramp Bark, Fluid Extract Falsi corn, Fluid Extract Senna, each 8 fl. ounces. Fluid Extract Mitehella 12 flounces, Fluid Extract Catnep 4 flounces, Spirit of Nitrous Ether 4 tl. ounces, Oil of Cassia 20 minims, Oil of Nutmeg 30 min- ims, Sugar 8 ounces av., Alcohol 2 pints. Water sufficient to make 1 gallon. Mix the Fluid Extracts and Spirit of Nitre, dissolve the Oils in the Alcohol and add to the solution _> pints of Water, mix this with the Fluid Extracts, etc., dissolve the Sugar in the mixture and add enough Water to make a gallon. The dose of this preparation is from 1 to j teaspoonfuls four times a day. 1078 STANDARD PROPRIETARY REMEDIES. 4036. Aletris Cordial. This is similar to the old eclectric preparation known as " Mothers' Cordial." The following formula will make a satisfactory prep- aration : Unicorn Root (Aletris), 8 ounces. Catnep Herb, 4 ounces. Cramp Bark, 4 ounces. Partridgeberry Leaves, 8 ounces. Blue Cohosh, 2 ounces. Cinnamon Bark, 1 ounce. Orange Peel, 1 ounce. Caraway Seed, ^ ounce. Sugar, 2^ pounds av. Alcohol, 2^ pints. Water, sufficient to make 1 gallon. Grind the drugs to a coarse powder and macerate 24 hours with the Alcohol mixed with an equal measure of Water, then percolate, adding Water after the liquid has disappeared from the surface of the drugs, and continue the percolation with Water until 6^ pints of the liquid are obtained ; filter, dissolve the Sugar in the filtrate and add enough Water to make a gallon of the finished cordial. The dose is a teaspoonful to a tablespoonful four times a day. 4037. Favorite Female Remedy. Witch Hazel Bark, 8 ounces av. Unicorn Root, 8 ounces av. Senna Leaves, 6 ounces av. Catnep Herb, 4 ounces av. Life Root Plant (Senecio Aureus), ... 4 ounces av. Vervain Herb, 4 ounces av. Black Haw Bark, 4 ounces av. Cinnamon Bark, ^ ounce av. Nutmeg, Y% ounce av. Sugar, 8 ounces av. Spirits of Nitre, 4 fl. ounces. Alcohol, 3 pints. Water, sufficient to make 1 gallon. Grind the drugs to a coarse powder, mix the Alcohol with 3 pints of Water, moisten the drug with 2 pints of the mixture and pack firmly in the water-bath percolator, pour the remainder of the mix- STANDARD PROPRIETARY REMEDIES. 1079 ture upon the drugs and set in a warm place for two days, then heat moderately and, after one hour, begin to percolate, adding Water to the drugs and continuing the heat and percolation until 7 pints are obtained ; to this add the Spirits of Xitre, dissolve the Sugar in the mixture, add enough Water to make a gallon, allow to stand a few days and filter. The dose is a teaspoonful to a tablespoonful four times a day. 4038. Female Pills. Under this title a great many pills are found in the market, most of them being indirectly advertised to "cure irregularity," and sold at an exorbitant price. A variety of formulas for Female Pills will be found among the Pills, or the following may be used : Ergotin, 100 grains. Extract Hellebore, 50 grains. Myrrh 50 grains. Sulphate of Iron, 50 grains. Aloin, . 20 grains. Make into 100 pills. The dose is 1 to 3 pills two or three times a day. HAIR DYES, RESTORATIVES, AND TONICS. Preparations for the hair, to dye or change its color and promote its growth, are extensively sold as proprietary remedies. The fol- lowing formulas are the best of the kinds used for their purposes : HAIR DYES. 4039. " Lightning Dye," Black, for the Hair and Whiskers. This is similar to the dye used by barbers. Ii is composed of a mordant and a dye, as follows : 1 . MORDA N 1 . Pyrogallic And . . 3 drachms. hoi 5 fl.ou Water . . . . 1 1 fl.ouncei Mix and dissolve. 1080 STANDARD PROPRIETARY REMEDIES. . NO. 2. BLACK DYE. Nitrate of Silver (Crystals), 2 ounces av. Aqua Ammonia, q. s., or about 4 fl. ounces. Distilled Water, q. s., or about 12 fi. ounces. Dissolve the Nitrate of Silver in 8 fl. ounces of the distilled Water and add 3 fl. ounces of Aqua Ammonia. This will produce a dark brown, precipitate. Continue to add Aqua Ammonia in small quantities until the precipitate is entirely redissolved, then add enough distilled Water to make a pint. In making this preparation for a black dye no more Aqua Ammo- nia must be used than is necessary to dissolve the precipitate, for a larger quantity than is necessary lightens the color. 4040. Lightning Dye — Brown. Nitrate of Silver, 1 ounce av. Aqua Ammonia, q. s., or about 2 fl. ounces. Carbonate of Sodium (Sal Soda), .... 3 drachms. Water, q. s., or about 10 fl. ounces. Dissolve the Nitrate of Silver in 8 ounces of Water and add Aqua Ammonia until the precipitate which is formed is dissolved ; dissolve the Sal Soda in the solution and add enough Water to make 1 2 fl. ounces, and, after standing a few days, decant. Use the same mordant for this dye as for the black. To apply these dyes the hair or whiskers are first washed with soda water or soap suds to remove any grease or oil, the mordant is then applied and allowed to dry ; the dye is then put on carefully with a tooth-brush or other convenient utensil and dried by fanning; the hair, when dry, is then washed with soapsuds, to remove any superfluous dye, and dried. Stains on the skin may be removed by rubbing them with the fol- lowing solution : Sulphate of Potassium 1 ounce. Water, 1 pint. Dissolve. 4041. Hair Dye — Black. (One Preparation.) Nitrate of Silver, 2 ounces Nitrate of Copper, 30 grains. Water of Ammonia, about 4 fl. ounces. Distilled Water, enough to make a pint. STANDARD PROPRIETARY REMEDIES. 1081 Dissolve the Nitrate of Silver and Copper in 8 ounces of distilled Water and gradually add the Water of Ammonia until the precipi- tate first formed is redissolved, then add sufficient distilled Water to make a pint. This dye may be used without a mordant. 4042. Blondine, or Golden Hair Coloring. What is sold on the market for the purpose of bleaching the hair or producing a blonde color is simply Peroxide of Hydrogen Solu- tion. It cannot readily be prepared except in a chemical laboratory. The hair is first washed in a weak solution of soda to remove any grease or oil, and then dried by ironing it with a warm flat-iron. The solution is then applied and dried in the same manner, several applications often being necessary to produce the desired color. HAIR RESTORATIVES. These preparations, which are designed for changing gray hair to its former natural color, have had a very extensive sale in past years, and still sell considerably. They are generally made to serve as invigorator and dressing for the hair as well as to restore the color. They all act by the absorption of lead and sulphur, and their conversion into sulphide of lead in the hair when exposed to light. It is necessary that these preparations be protected from the light. The following formulae make preparations similar to those most popular in the market : 4043. Hair Renewer or Balsam. Acetate of Lead i r j ounces av. Lac Sulphur (Precipitated Sulphur), ... 2 ounces av. Tincture of Cantharides 1 fl.ounce. Glycerin, 1 pint. Alcohol '-• pint. Oil of Citronella, - 1 fl.drachms. oil of Bergamot 1 fl.drachm. Water, suffii ient u> make a gallon, Dissolve the Oils in the Alcohol, add the Glycerin and Tincture of Cantharides and mix with the Water, then add the Sulphur and A( < tate "I I .ead. 1082 STANDARD PROPRIETARY REMEDIES. 4044. Hair Vigor or Vitalizer. Precipitated (Lac) Sulphur 2 ounces av. Nitrate of Lead i 1 /^ ounces av. Tincture of Cantharides, 2 fi. ounces. Glycerin, 1 pint. Alcohol, y 2 pint. Oil of Lavender, .... y 2 fl. ounce. Essential Oil of Almonds, 30 minims. Water, enough to make a gallon. Mix the Sulphur and the Lead and add to half a gallon of the Water, dissolve the Oils in the Alcohol, add the Tincture of Can- tharides and Glycerin and add to the mixture ; then add enough Water to make a gallon. The Nitrate of Lead is to be preferred to the Acetate on account of the disagreeable odor of the Acetate. If the odor of rose is preferred to Lavender, 3 pints of Rose Water may be used, the Oil of Lavender being omitted. 4045. Hair Renovator. Acetate or Nitrate of Lead, iJ-2 ounce av. Hyposulphite of Sodium, 5 ounces av. Glycerin, 1 pint. Alcohol, y 2 pint. Oil of Lemon, 2 fl. drachms. Essential Oil or Almonds, Yi fl. drachm. Oil of Cloves, y 2 fl. drachm. Rose Water, 2 pints. Water, sufficient to make a gallon. Dissolve the Lead and Hyposulphite of Sodium, each separately, in 2 pints of hot Water and mix the solutions ; dissolve the Oils in the Alcohol, add 2 pints of Water and rub with half ounce Carbon- ate of Magnesium in a mortar, filter and add the filtrate to the other mixture, then add the Glycerin and enough Water to make a gallon. This makes a preparation without sediment, which is much cleaner to use than those containing the Precipitated Sulphur. It must be kept from the light. 4046. Hair Restorer. (Two Preparations.) The following is similar to several preparations .that have been put upon the market, containing two bottles. It has no particular STANDARD PROPRIETARY REMEDIES. 1083 advantage over Xo. 4044, except that the bottles may be exposed to light without causing precipitation. NO. I SOLUTION. Hyposulphite of Sodium 2 ounces av. Rose Water 1 pint. Water 1 pint. Alcohol, yi pint. Mix and dissolve. Xo. 2 SOLUTION. Xitrate of Lead, ... 1 ounce av. Glycerin 4 fl.ounces. Distilled Water, 3 pints. Mix and dissolve. Apply Xo. 1 solution to the hair and allow to dry, then applv Xo. 2 solution, rubbing it in thoroughly with a hair brush. 4047. Mrs. Allen's Hair Restorer. From analyses of this preparation, conducted separately by Witt- stein and Musset, it is shown to contain Sulphur, Sugar of Lead, and Glycerin, with aromatic water. The following formula very nearly corresponds with the analysis : Lac Sulphur 135 grains. Acetate of Lead 190 grains. ( rlycerin, 3^ fl ounces. Water, ..11 fl.ounces. Cologne or bulk perfume, .... 1 ounce. Mix. This is one of the oldest and best known I lair Restorers. HAIR TONICS. 4048. Katharion Tonic. Castor Oil \ fl.ounces. Tincture Cantharides ( 1 S80), 4 fl.drachms. Tannic Acid, 30 grains. ( Ml ( Ttronella 30 minims. Oil Bergamol 30 minims. ( )il ( lloves 40 minims. Oil Lavender Flowers ... 60 minims. ( )il Rosemary, 60 minims. Alcohol 1 - fl.ounces. M t 1084 STANDARD PROPRIETARY REMEDIES. 4049. Hair Tonic. Tincture of Cantharides 4 fl. drachms. Water of Ammonia, 1 fl. ounce. Cologne, 2 fl. ounces. Glycerin, 4 fl. ounces. Borax 2 drachms. Bay Rum, 4 fl. ounces. Water, 4 fl. ounces. Mix. This is an excellent tonic, shampoo, or dressing : 4050. Hair Lotion or Wash. To prevent the Hair from falling out and promote its growth. Tincture Cantharides, 2 fl. drachms. Water of Ammonia, 1 fl. drachm. Glycerin, 1 fl. ounce. Bay Rum, 5 fl. ounces. Rose Water, 10 fl. ounces. Mix them. This is applied as a lotion for baldness, etc., also as a dressing. 4051. Carboline Hair Grower. Neutral Paraffin Oil 1 pint. Cantharides Tincture, 4 fl. drachms Euphorbium, 20 grains. Oil of Rosemary, 4 fl. drachms. Oil of Cassia, 20 drops. Ori of Cloves, 5 drops. Heat the Euphorbium and Tincture of Cantharides for 2 hours with the Paraffin Oil, then strain and add the other Oils. This is used for promoting the growth of the hair, baldness, etc. It should be rubbed thoroughly on the scalp. HEART PREPARATIONS. The sale for proprietary heart medicines has never been large, for the reason that people who have any trouble with this organ, if pos- STANDARD PROPRIETARY REMEDIES. 1085 sible, seek the advice of physicians. A very few preparations for heart troubles are found on the market, all similar in composition. 4052. Heart Corrector or Regulator. Digitalis, in coarse powder, 1 ounce. Hyoscyamus, in coarse powder, 1 ounce. American Hellebore (veratrum-viride), ... 2 drachms. Diluted Alcohol, sufficient to make 1 pint. Percolate the drugs with the Diluted Alcohol until a pint of Tinc- ture is obtained. The dose is from ){ to 1 teaspoonful for palpita- tion or other disturbances of the heart. HYPOPHOSPHITE COMPOUNDS. The Compounds of Hypophosphites are considerably sold as proprietary medicines, some special makes being quite popular, but as they have been noticed under solutions, emulsions, malt prepara- tions, syrups and other headings, it will be unnecessary to give fur- ther formulas for them in this department. INHALANTS AND INHALERS. Inhalants are designed to be used, by being vaporized in Inhalers v designed for that purpose, ami are employed for the relief or cure of asthma, catarrh, colds, bronchitis, hay-fever, and diseases affecting the air passages. A greal variety of Inhalers arc made, the most convenient and practical beingthose which admit of the passage of air through tubes of paper, wood, or other absorbing substance or loose fibrous material which is saturated with the In- halant. The air then being drawn through these saturated tube-, or substances carries the vapor of the Inhalant to the diseased part, where it exerts its curative action. Other forms of Inhalers are those by which a current of air is made to pass through a solution of some volatile medicinal substance contained in a bottle, 1086 STANDARD PROPRIETARY REMEDIES. The following Inhalants may be put up as proprietary. 4053. Carbolate of Iodine Inhalant. Carbolic Acid (Crystals), 120 grains. Glycerin, 1 drachm. Tincture Iodine, 3 drachms. Camphor, in powder 90 grains. Water of Ammonia, q. s. Dissolve the Carbolic Acid in the Glycerin, add the Tincture of Iodine and Camphor, and then add Water of Ammonia drop by drop until the solution is nearly colorless. 4054. Excelsior Inhalant. Carbolic Acid (Crystals), 1% ounce av. Camphor, 2 ounces av. Oil of Eucalyptus, . . . . . % fl. ounce. Oil of Sassafras, 1 fl. drachm. Oil of Tar, . . . . 1 fl. drachm. Oil of Hemlock, 1 fl. drachm. Mix and dissolve. This is an excellent Inhalant and may be put up by any other name than the one in the title. It is used for catarrh, etc. 4055. Menthol Inhalant. Menthol Inhalers are made by enclosing crystallized Menthol or pip-menthol loosely packed in a glass tube which may be opened at both ends. The air being inhaled through the tube is charged with the menthol vapor. They are used chiefly for headache. A solu- tion of Menthol may also be prepared by dissolving 1 ounce of Menthol in 8 ounces of Alcohol. This may be used with any of the ordinary forms of tubular inhalers. INJECTIONS. Injections which are sold as proprietary remedies are mostly for private diseases, but in regular pharmacy Hypodermic Injections of Apo-morphine, Ergotin and Morphine are official in the Br. P., and many others are prescribed or employed by physicians in their prac- STANDARD PROPRIETARY REMEDIES. 1087 tice. In this department the proprietary injections only will be noticed. 4056. Injection Brou. Acacia, in coarse powder ' . 2 drachms. Calamine, . . 1 drachm. Acetate of Zinc, 1 drachm. Tincture of Catechu, 4 fl. drachms. Tincture of Opium and Saffron, .... 4 fl. drachms. Water sufficient to make a pint. Dissolve the Acacia and Acetate of Zinc in the Water and tritu- rate with the Calamine in a mortar, then add the tinctures. This is to be shaken before using. Ordinary Laudanum may be used in- stead of the Tincture of Opium and Saffron. 4057. Rose Injection or Rose Wash. Sulphate of Zinc, 1 drachm. Tincture of Catechu, 4 fl. drachms. Tincture of Opium, 4 fl. drachms. Glycerin, i fl.ounce. Rose Water, 14 tl. ounces. M i.\ them. 4058. Compound Hydrastis Injection. Fluid Hydrastis, or Aqueous Fl. Extract Hydrastis. 1 fl.ounce. Sulphate of Zinc 1 drachm. Glycerin i tl. ounce. rincture of Catechu 4 fl. drachms. Rose Water 14 fl. ounces. Mix them. IODIDE ALTERATIVES. The following preparations have hern popular as proprietary medicines with published formulas of composition, and, sold mainly 1 ription of physicians. 4059. Iodide of Potassium Elixir Compound. •• lodia " Alterative Elixir. Under the name " lodia," Battle & Co., Chemists, Corporation of St. Louis, have mide and sold an alterative preparation, claiming it 1088 STANDARD PROPRIETARY REMEDIES. to contain certain alterative preparations combined with Iodide of Potassium and Phosphate of Iron. A good preparation of this kind, containing similar ingredients as is claimed for this, may be made as follows : Stillingia, in coarse powder, 2 ounces av. Prickly-Ash Bark, % ounce - Saxafraga, 1 ounce. Yellow Parilla, 1 ounce. Blue Flag, % ounce. Iodide of Potassium, 256 grains. Phosphate of Iron (Scale salt 1880), . .128 grains. Diluted Alcohol, 16 n. ounces. Water, sufficient to make 1 pint. Mix the powdered drugs and percolate with the diluted Alcohol first, and then with Water until 15 fl. ounces are obtained. Dis- solve the Iodide of Potassium in the tincture and the Iron Salt in 1 ounce of hot Water, and gradually add the tincture to the Iron solution and after standing filter. By using tasteless " Tincture of Iron " a better preparation may be made. 4060. Elixir Iodides and Bromides of Calcium Compound. " Elixir Iodo-Bromidc of Calcium Compound." Under the title " Elixir Iodo-Bromide of Calcium Compound," Tilden & Co. of New Lebanon, have had an extensive sale for an alterative compound, claiming to contain many valuable Alterative Salts and medicines. This is noted on page 292. The following formula is suggested by C. S. Hallberg of Chicago, in a paper read before the Illinois Pharmaceutical Association at Bloomington, 111., October 1, 1884 : Calcium Bromide, . . . . 256 grains. Sodium Iodide, 256 grains. Potassium Iodide, 256 grains. Magnesium Chloride, 256 grains. Fluid Extract Sarsaparilla Compound, ... 2 ounces. Fluid Extract Stillingia Compound, ... 2 ounces. Elixir Orange, 4 ounces. Sugar, 4 ounces. Water sufficient to make a pint. Dissolve the Salts in the Water, add the Sugar, and to this syrup add the fluid extracts previously mixed with the Elixir Orange. STANDARD PROPRIETARY REMEDIES. 10S9 After standing two days filter, adding Water to make the measure 16 fi.ounces. KIDNEY AND LIVER REMEDIES. Many of the remedies which are designed to act on the Kidneys and Liver are noticed under ofher headings, and only those which are known in the market by the name of Kidney and Liver Reme- dies or Cures, or by other similar titles are included in this section. There has always been a good demand for proprietary remedies for diseases of the kidneys, bladder and urinary organs. In the earlier days, Vaughn's Lithontriptic and Constitution Water were popular. More recently, Helmbold's and other Buchus had a big run ; still more lately Diuretic Elixirs of various kinds have had their day, and now a large family of Liver and Kidney Remedies have swept everything else out of the way, and are having the market all to themselves. So extensively have some of these late remedies been advertised and pushed, that it is now difficult to find a man, woman, var child who has not some serious kidney difficulty. In making the formulae for those preparations we would have pre- ferred to confine their use to the kidneys, bladder, and urinary organs, but we must follow the fashion and include the liver also. The formulae which follow make preparations similar to those most popular in the market, and are representative of different kinds of kidney and liver remedies. 4061. Diuretic Cordial, Kidney and Liver Remedy. Liverwort, herb (Hepatica), 16 ounces av. Dandelion Root, 8 ounces av. Digitalis, leaves 1 ounce av. Hydrangea Knot, 4 ounces av. Wintergreen, herb, 2 ounces av. Nitrate of Potassium, 3 ounces av. Sugar, \2 ounces av. Alcohol, i'j pints. Menthol, 5 grains. Water, sufficient to make a gallon. Grind the herbs, etc., to a coarse powder and, having mixed the Alcohol with 4 pints of Water, moisten the powder with 2 pints of the mixture and macerate in a covered vessel for 24 hours ; transfer to the water-bath percolator, pack moderately, pour upon it the r< tier of the liquid and set in a warm place for one day; then heat 1090 STANDARD PROPRIETARY REMEDIES. very moderately and, after one hour, begin to percolate, adding Water through the percolator after the liquid has disappeared from the surface, and continuing the heat and percolation until 7^ pints have passed ; in this dissolve the Nitrate of Potassium and Sugar, and, after standing 'a few days, filter. This may be made by the ordinary method of percolation instead of by water-bath, but the latter is preferable. If it is desired to use fluid extracts instead of the drugs, the for- mula is as follows : Fluid Extract of Liverwort 16 fl. ounces, Fluid Extract of Dandelion 8 fl. ounces, Fluid Extract of Hydrangea 4 fl. ounces, Fluid Extract of Digitalis 1 fl. ounce, Essence of Winter- green 1 fl. drachm, Nitrate of Potassium 3 ounces av., Sugar 12 ounces av., Alcohol 10 fl. ounces, Menthol 5 grains, Water 5 pints. Mix the Fluid Extracts, Alcohol, and Water, add the Essence of Wintergreen and Menthol, dissolve the Sugar and Nitre in the liquid, and filter. This is very similar to, but considerably stronger than, the " Safe " cure. The usual dose is from a dessertspoonful to a tablespoqnful, the latter containing about 5 grains of Nitrate of Potassium. 4062. Kidney and Liver Remedy. Dandelion Root, 12 ounces av. Buchu Leaves, short, 8 ounces av. Liverwort, herb, 8 ounces av. Hydrangea Root, 4 ounces av. Spirit of Nitrous Ether, 8 fl. ounces. Sugar, 12 ounces av. Alcohol, 2 pints. Water, sufficient to make a gallon. Grind the drugs to a coarse powder and, having mixed the Alco- hol with 4 pints of Water, moisten the powder with 2 pints of the mixture and macerate in a covered vessel for 24 hours ; transfer to the water-bath percolator, pack moderately, pour upon it the remainder of the liquid and set in a warm place for one day, then heat very moderately and, after one hour, begin to percolate, adding Water to the drugs after the liquid has disappeared, and continuing the heat and percolation until 7 pints have passed ; to this add the Spirit of Nitre and the Sugar, and enough Water to make a gallon, and, after standing a few days, strain. This may be made by the ordinary method of percolation instead of by water-bath. The dose is a dessertspoonful to a tablespoonful. STANDARD PROPRIETARY REMEDIES. 1091 It may be made from fluid extracts by taking Fluid Extract of Dandelion 12 fl. ounces, Fluid Extract of Buchu S fl. ounces, Fluid Extract of Liverwort S fl. ounces, Fluid Extract of Hydrangea 4 fl. ounces, Spirit of Nitre, sweet, 8 fl. ounces, Sugar 12 ounces av., Alcohol 1 pint, Water \% pints. Mix, dissolve the Sugar, and filter. 4063. Buchu Compound. Buchu Leaves, short 12 ounces av. Juniper Berries, S ounces av. Liverwort, herb, 4 ounces av. Hydrangea Root, 4 ounces av. Acetate of Potassium, 4 ounces av. Spirit of Nitrous Ether, 4 fl. ounces. Sugar, 12 ounces av. Alcohol, 2>4 pints. Water, sufficient to make a gallon. Grind the drugs to a coarse powder and, having mixed the Alco- hol with 4 pints of Water, moisten them with 2 pints of the mixture and macerate in a covered vessel for 24 hours ; transfer to the water-bath percolator, pack moderately, pour upon them the remain- der of the liquid and set in a warm place for one day, then heat very moderately and, after one hour, begin to percolate, adding Water to the drugs after the liquid has disappeared from the sur- face, and continuing the heat and percolation until 7% pints have passed ; in this dissolve the Sugar and Acetate of Potassium and, after standing a few days, filter. This is somewhat similar to the Diuretic Elixir, Buchu, Juniper, and Acetate of Potassium, which has been quite popular. 4064. Nephritic Compound. Buchu Leaves, short, 12 ounces av. Hydrangea Root, . 12 ounces av. Digitalis Leaves, 3 ounces av. Juniper Berries, S ounces av. Nitrate of Potassium, 3 ounces av. Essence of Wintergreen, 1 B.ounce. Alcohol, 3 pints. Water, sufficient to make a gallon. Grind the drugs to a coarse powder, moisten them with sufficient Alcohol and Water mixed in equal quantities by measure, and 1092 STANDARD PROPRIETARY REMEDIES. macerate for 24 hours, then transfer to a water-bath percolator, pack firmly, cover with a mixture of equal measures of Alcohol and Water, heat moderately and percolate with the same until the quan- tity of Alcohol which is directed has been used ; then add Water to the drugs, and continue the percolation, until one gallon of the percolate is obtained. Dissolve the Nitrate of Potassium in this and filter. The dose is a dessertspoonful to a tablespoonful as a remedy for kidney troubles. 4065. Kidney and Liverwort Tea. Liverwort, herb, cut, 8 ounces. Dandelion Root, cut, 4 ounces. Digitalis Leaves, cut, ^ ounce. Hydrangea Root, cut, 2 ounces. Wintergreen, herb, cut, 1 ounce. Peppermint, herb, cut, 1 ounce. Nitrate of Potassium, powder, 3 ounces. Mix thoroughly, and put up in packages, holding about 2 ounces. Directions for use : Steep the contents of the package in a quart of water, with gentle heat, for two hours, then strain off i}4 pints, and add to it half a pint of alcohol and 2 ounces of sugar. Adult dose of this preparation a wine-glass full (1 flounce ), four times a day. Kidncywort. — A proprietary medicine by this title is put up by Wells, Richardson & Co. of Burlington, Vt., both in a liquid and dry form. The dry Kidneywort is a mixture of drugs, as dandelion, hydrangea, etc., and extracts of other drugs, with roasted beans coarsely ground. The liquid contains the strength of similar medicinal ingredients. LINIMENTS. Proprietary preparations that are sold as Liniments may naturally be divided into two classes : A, those intended for internal and ex- ternal use, and B, those intended for external use only. The former are used the same as the Balms and Pain Killers as general pana- ceas, and consist mostly of oils or volatile substances dissolved in Alcohol or similar solvents ; the latter are usually mixtures of volatile oil and substances with some fixed or mineral oil, and are used externally for pain, swellings, sores, etc. The following formulse are representatives of popular liniments. Others will be found under other headings throughout this work. STANDARD PROPRIETARY REMEDIES. 1093 CLASS A. — For External and Internal Use. 4066. Arnica Liniment. Arnica Flowers, . 16 ounces av. Smartweed Herb, 18 ounces av. Marigold Flowers, 4 ounces av. Oil of Sassafras, 3 fl. ounces. Oil of Hemlock, 1 fl. ounce. Oil of Origanum, y? fl. ounce. Camphor, 1 ounce av. Alcohol, 7 pints. Water, a sufficient quantity to make a gallon. Reduce the drugs to a coarse powder and pack firmly in the water- bath percolator. Pour upon them 4 pints of alcohol, and macerate in a warm place for 24 hours, then heat very moderately for one hour, and begin to percolate slowly, adding first the remaining three pints of alcohol, and when it has disappeared from the surface con- tinue the percolation with water until 7^ pints have passed. To this percolate add the oils and the camphor and dissolve ; filter if necessary. This is for external or internal use. 4067. Cocaine Liniment. Hydrochlorate of Cocaine, 30 grains. Oil of Hemlock, 1 fl. ounce. Oil of Sassafras, 1 ounce. Alcohol, 14 fl. ounces. Mix and dissolve. The dose is 20 to 30 minims. It is also used externally for pains, etc. 4068. Eclectric Liniment. Oil of Origanum 2 fl. ounces. Oil of Hemlock 4 fl.oum Oil of Turpentine 4 fl.ounces. Oil of Sassafras, 2 fl.oum Oil of Amber )z fl.ounce. Camphor, 2 ounces av. Capsicum ia fine powder 1 ounce av. Myrrh in fine powder 1 ounce av. Waur of Ammonia 4 fl.ounces. Alcohol, sufficient to make a gallon. Mix and macerate for 7 days, then filter. For external or internal use. 1094 STANDARD PROPRIETARY REMEDIES. 4069. Indian Liniment. Oil of Sassafras, 1 ounce. Oil of Origanum, 1 ounce. Oil of Pennyroyal, 1 ounce. Oil of Hemlock, 1 ounce. Tincture of Capsicum, 2 ounces. Alcohol, 26 ounces. Mix them. This is a popular general panacea for pain, colic, etc. Dose 20 to 30 minims or more. 4070. Menthol Liniment. Menthol, 1 ounce. Tincture of Capsicum, 4 ounces. Sulphate of Morphine, 30 grains. Alcohol, 27 ounces. Mix and dissolve. This is used externally for pain, rheumatism, headache, etc., and may be taken in doses of 20 to 30 minims. 4071. "Ready Relief." Druggists have no right to use the title " Ready Relief " on their labels and wrappers, as it is claimed as proprietary by Radway & Co. This formula, however, makes a similar preparation. Camphor, 3 ounces av. Capsicum, .8 ounces av. Oil of Turpentine, 2 flounces. Stronger Waters of Ammonia, 8 fl. ounces. Alcohol, 1 gallon. Mix and macerate for a week, shaking daily, then filter. 4072. Thymol-Chloral Liniment. Thymol 1 ounce. Chloral Hydrate, 1 ounce. Tincture of Capsicum, 4 ounces. Alcohol, 26 ounces. Mix, dissolve and filter. For rheumatism, pain, etc. Dose 20 to 30 minims when taken. STANDARD PROPRIETARY REMEDIES. 1095 4073. Smartweed Compound or Extract. Smartweed, leaves or herb, 20 ounces. Alcohol, 6 pints. Water, 2 pints. Camphor, 6 drachms. Oil Hemlock, ) , 1 - each, 1 ounce. Oil Sassafras, ) Grind the Smartweed to a coarse powder, and moisten it with 1 pint of the Alcohol ; pack tightly in a percolator, and pour upon it the remaining Alcohol ; cover closely and allow to stand four days ; begin the percolation, and when no more Alcohol remains on top of drug, add the water. When the liquid has ceased to drop, press out what remains in the drug in the percolator, and add to the last portion. In the 4 pints first obtained by percolation (before the Water is added to the drug in the percolator), dissolve the Camphor and Oils, and when the last portion of the percolate and that from the pressure is obtained, add it gradually to the portion in which the Oils, etc., have been dissolved, and filter, adding Alcohol enough to make 1 gallon. For external and internal use. 4074. Wizard Liniment. Oil of Sassafras, S fl.ounces. Oil of Cloves, 2 fl.ounces. Oil of Turpentine, 4 fl.ounces. Stronger Water of Ammonia, 1 flounce Ether (Sulphuric), 4 fl.ounces. Chloroform, 1 fl. ounce. Camphor 2 ounc< Alcohol sufficient to make a gallon. Mix and dissolve. For internal or external use. Under the title Wizard oil, Wizard Liniment, Wizard Balm, Golden Relief, Golden Oil, and by many other similar names, a .lass..!" preparations for internal and external use are largely sold. In the preceding pages many good formulas for such preparations will be found under various titles. They are mostly compounds of aromatic oils with camphor and chloroform or ether, and prompt and diffusive remedies to relieve cramp, pain, colic. The profit on these preparations is large, and as they may readily be pre- pared there is no reason why druggists should not as well secure it to themselves as to pay it to others. 1096 STANDARD PROPRIETARY REMEDIES. 4075. Eclectric Oil. The following formula has been published as similar to Thomas'. Camphor, y 2 ounce. Oil Gaultheria, ^2 ounce. Oil Origanum ^4 ounce. Chloroform, 1 ounce. Laudanum, 1 ounce. Oil Sassafras 1 ounce. Oil Hemlock, 1 ounce. Oil Turpentine, 1 ounce. Balsam Fir, 1 ounce. Tincture Guaiacum 1 ounce. Tincture Catechu 1 ounce. Alcohol, 4 pints. Alkanet, sufficient to color. Several other formulas are given in this work which make prep- arations similar to this. CLASS B. — For External Use only. 4076. Fluid Lightning. Aconitia, 1 grain. Essential Oil of Mustard 1 drachm. Glycerin 1 ounce. Alcohol, 4 ounces. Mix. This is a valuable external preparation for headache, neuralgia, rheumatism, and all nervous pains. 4077. "Gargling Oil" Liniment. Camphor, 8 ounces av. Oil of Amber, 2 fi. ounces. Origanum Oil, 1 flounce. Carbolic Acid, 4 ounces av. Oil of Turpentine, 3 pints. Crude Petroleum Oil, 4 pints. Stronger Water of Ammonia, 2 fl. ounces. Mix and dissolve. This is somewhat like but we think a much better preparation than Gargling Oil. STANDARD PROPRIETARY REMEDIES. 1097 4078. Iodide of Ammonium Liniment. Iodine, 1 drachm. Camphor, J4 ounce. Oil Rosemary, ) , a 1 , _., ' c each, 2 drachms. Oil Lavender, ) Water of Ammonia, q. s.. or 1 ounce. Alcohol , 1 pint. Dissolve the Iodine in the Alcohol and add the Camphor and the Oils, then add Water of Ammonia enough to remove the dark color of the mixture, or change it to a light straw color. 4079. Mexican Liniment. Olive Oil, 2 pints. Camphor, 2 ounces. Oil Origanum, 1 ounce. Oil Sassafras, 1 ounce. Water of Ammonia, 8 ounces. Dissolve the Camphor in the Oils and mix well with the Water of Ammonia. 4080. Nerve and Bone Liniment. Oil of Origanum, 1 fl.ounce. Oil of Rosemary .1 fl.ounce. Oil of Amber, 1 fl.ounce. Oil of Hemlock, 1 fl.ounce. Camphor 4 ounces av. Oil of Turpentine 3 pints. Linseed Oil, 5 pints. Mix and dissolve. 4081. Ready Oil Liniment. ( )il < Origanum 1 fl.ounce. ( HI Sassafras 1 A.qi Oil 1 teralock 1 fl.ounce. ( >il Peppermint, ... 2 fl. drachms. Chloroform, ... 1 fl. drachms. ( lamphor 1 ounce av. il Paraffin ' >il 1 2 fl.ounces Mix the* Oils and dissolve the Camphor in the mixture. Cotton- Seed < HI or Linseed < »il may be used instead of the Paraffin < HI. 'This is a good general Oil Liniment. 1098 STANDARD PROPRIETARY REMEDIES. 4082. Rheumatic Liniment. Oil of Sassafras, 6 flounces. Oil of Origanum, . 4 flounces. Oil of Cedar, 2 ft. ounces. Oil of Amber, 1 ft. ounce. Camphor, 8 ounces av. Oil of Turpentine sufficient to make a gallon. Mix and dissolve. This is said to be quite similar to the popular preparation known as " St. Jacob's Oil." 4083. "Spavin Cure." This comes properly under the head of Liniments, but it is chiefly used in veterinary practice. It is, however, an excellent absorbent liniment for man or beast. An excellent application for swellings or lameness of any kind, but it must not be used internally. Camphor, 4 ounces av. Oil of Turpentine, 4 fl. ounces. Tincture of Iodine, 4 fl. ounces. Bichloride of Mercury, 30 grains. Oil of Spike, 2 flounces. Oil of Amber, 2 ft. drachms. Mix and dissolve. 4084. Veterinary Liniment. Oil of Amber, 2 flounces. Camphor, 4 ounces av. Carbolic Acid, 3 ounces av. Oil of Tar, 2 flounces. Oil of Sassafras, . 4 fl. ounces.- Oil of Turpentine, 2 pints. Crude Petroleum, 5 pints. Mix and dissolve. NERVINES, HYPNOTICS AND SEDATIVES. Nervines and Sedatives, as a class, do not have a large sale as proprietary medicines, which is rather strange considering the prev- alence of nervous diseases. It is to be inferred that persons thus afflicted either apply to their physician, or purchase some nervine of their druggist with which they have become familiar. STANDARD PROPRIETARY REMEDIES. 1099 It would seem from these conditions that there is a good opening for a proprietary nervine, which druggists may themselves prepare and put before their patrons. Many formulas for such preparations are given throughout this work, but the following are calculated, particularly, to put up as proprietary : 4085. Nervine Tonic. Scullcap, in coarse powder, 8 ounces av. Hops, in coarse powder, 8 ounces av. Hyoscyamus, in coarse powder, 8 ounces av. Valerian, in coarse powder, 8 ounces av. Bromide of Ammonium, 4 ounces av. Ether (Sulphuric), 4 fl. ounces. Alcohol, 3 pints. Sugar, 2 pounds av. Water, sufficient to make 1 gallon. Mix the powders, and having mixed the Alcohol with 3 pints of Water, pour upon them 2 pints of the liquid and macerate for 24 hours, in a warm place ; then transfer to the water-bath percolator, pack firmly, pour upon it the remaining Alcohol and Water, and set in a warm place for one day ; then heat very moderately, and after one hour begin to percolate, adding Water to the drugs when the liquid has disappeared from the surface, and continuing the heat and percolation until 7 pints have passed ; to this add the Ether and dissolve in the liquid, by agitation, the Bromide of Ammonium and Sugar. This is an excellent tonic nervine for general nervous depression and irritation, nervous headache, neuralgia, sleeplessness, epilepsy, etc. The dose is from a teaspoonful to a tablespoohful, as required. 4086. Nervine Elixir. Bromide of Ammonium 1 ' 4 ounce av. Valerianate of Ammonium, %. ounce av. Fluid Extract of Valerian i fl. ounce. Fluid Extract of Hyoscyamus i fl. ounce. Fluid Extract of Coca i fl.ounce. Syrup, 2 fl.ounces, Elixir simple, enough to make . . . . i pint Mix the liquids and dissolve the sails in the mixture ; after stand ing -• 1 hours filter. This is an excellent nervine and Anodyne 1100 STANDARD PROPRIETARY REMEDIES. Elixir, for nervousness, pain, neuralgia, hysteria, and all " nervous " troubles. Dose, from a teaspoonful to a tablespoonful, as required. 4087. Sedative Nervine Elixir. Bromide of Potassium, 640 grains. Sulphate of Morphine, 8 grains. Valerianate of Ammonium, 256 grains. Fluid Extract Valerian, 1 fl. ounce. Fluid Extract Hops, ]/?, fl. ounce. Water of Ammonia, 1 fl. drachm. Syrup, 2 fl. ounces. Elixir, simple, enough to make .... 1 pint. Dissolve the salts in the Elixir and Syrup, add the Fluid Extracts and the Water of Ammonia, let stand a day or two and filter. Dose, a teaspoonful to a dessertspoonful. 4088. Celery Compound. Several preparations of Celery compounded with other Nervines have had a good sale as proprietary medicines, under various titles, as " Celerina," Celery Cordial, Celery Compound, etc. The following formula will make a satisfactory preparation : Celery Seed, .1 ounce av. Coca Leaves, 1 ounce av. Black Haw Bark, 1 ounce av. Hyoscyamus Leaves, }4 ounce av. Orange Peel, 2 drachms. Sugar, 4 ounces. Alcohol, 6 ounces. Water, q. s., to make 1 pint. Grind the drugs to a coarse powder, mix the Alcohol with 6 ounces of Water, pour upon the drugs enough of the diluted Alcohol to cover, and macerate for 24 hours ; then heat moderately and perco- late, adding Water through the percolator until 14 fl.ounces are obtained ; in this dissolve the sugar and filter. The dose is a tea- spoonful to a dessertspoonful or more as a nerve tonic. 4089. Chloral-Bromide Compound. " Bromidia." Under the title " Bromidia," which is claimed as a trade-mark, Battle & Co., Chemists, Corporation of St. Louis, Mo., have pre- pared and extensively sold a preparation intended to be used as a STANDARD PROPRIETARY REMEDIES. 1101 nervine, sedative, and hypnotic. The following formula is based upon the qualitative composition of the preparation as published by them, but druggists are warned by them not to sell nor dispense any preparation other than their own as " Bromidia." Chloral, crystallized, Bromide of Potassium, Extract Cannabis Indica, Extract Hyoscyamus Water, sufficient to make Dissolve the Extracts in 4 ounces of boiling 4 ounces av. 4 ounces av. 16 grains. 16 grains. 1 pint. Water, rub the solu- tion with 1 drachm of Carbonate of Magnesium and filter. Dis- solve the Bromide of Potassium in 8 ounces of boiling Water and add the Chloral, mix the solutions and add Water enough to make 1 pint. This may be colored a little with a few grains Extract of Liquorice if desired. Uose 15 to 30 drops. 4090. Bromides Compound. A number of preparations of Bromides are sold as proprietary, as "Peacock's Bromides," and by other titles. The following formula makes a preparation similar to those found in the market. Bromide of Potassium, 640 grains. Bromide of Sodium, 640 grains. Bromide of Ammonium, 3S4 grains. . Bromide of Calcium, 192 grains. Bromide of Lithium, 64 grains. Water 8 fl. ounces. Extract of Vanilla, 1 flounce. Sugar, 10 ounces av. Rub the Bromides to a coarse powder. Mix the Water ami Extract of Vanilla and dissolve the Salts in the mixture; filter and dissolve the Sugar in the nitrate by agitation. Dose 1 to 2 fl. drachms in water. 4091. Chlorodyne. Chloroform Fluid Extract < lannabis Endica, Spirit of Ether Tincture < >pium deodorized, . I [ydrocyanic A< id 1 1 '. S. P.), ( Heoresin of ' lapsii um, . . . Dissolve the oleoresin in the Chlorofora and mix. 1 fl. ounce. 1 fl. ounce. 1 '.• fl. ounce. 1 '.• ll. ounce. 3 ll. drachms. 3 minims. Id the Spiril of Ether, 1102 STANDARD PROPRIETARY REMEDIES. 4092. Chlorodyne. Chloroform, 4 fl. drachms. Sulphuric Ether, 2 fl. drachms. Hydrocyanic Acid (U. S. P.), 4 fl. drachms. Tincture Capsicum, 4 -fl. drachms. Mucilage Acacia, 1 fl. ounce. Sulphate of Morphine, 20 grains. Oil of Peppermint, 8 minims. Treacle (Molasses), 4 fl.ounces. Mix the Chloroform with the Mucilage Acacia, add the Oil of Peppermint and Syrup and shake them well together. Dissolve the Sulphate of Morphine in the Tincture of Capsicum, and add to the mixture, and lastly add the Hydrocyanic Acid and mix. This is quite similar to the popular English Brown's Chlorodyne. It must be shaken before taking. The dose is 10 to 20 minims. 4093. Chlorodynia. Sulphate of Morphine, 15 grains. Chloroform, 1 fl. ounce. Alcohol, 1 fl. ounce. Fluid Extract Cannabis Indica, 1 fl. ounce. Glycerin, 1 fl. ounce. Hydrocyanic Acid, U. S. P., 15 minims. Peppermint Essence, 15 minims. Mix the liquids and dissolve the Morphine Salt in the mixture. This is one of the best forms of Chlorodyne, as it makes a clear preparation, not required to be shaken when taken. The dose is 10 to 30 minims. OINTMENTS AND SALVES. The sales of proprietary salves and ointments are perhaps as fre- quent as of almost any class of proprietary medicines ; and, although but few sell for more than twenty-five cents, the aggregate of sales is large. A great variety of these remedies are on the market ; but, with the exception of a very few, the public are not particular as to the preparation they have, provided, only, it is good for the pur- pose. Druggists can, therefore, put up their own ointments and salves from reliable formulas, and if the preparation is good, and the STANDARD PROPRIETARY REMEDIES. 1103 packages attractive, can secure most of the sales of such articles for their own preparations. Many formulas are given under other headings. The following are representatives of other popular ointments. 4094. Camphor Ice. Paraffin, 8 ounces av. White Petrolatum, 24 ounces av. Camphor, 6 ounces av. Oil of Xeroli, 5 minims. Oil of Bitter Almond, 20 minims. Oil of Cloves, 10 minims. Melt the Paraffin and Petrolatum together, reduce the Camphor to a coarse powder and dissolve it in the melted mixture, keeping at as low a temperature as it can he without solidifying. When all is dissolved strain while still fluid, add the perfuming oils and run in molds. 4095. Carbolic Salve or Ointment. Carbolic Acid (crystals), 1 ounce av. Yellow Wax, 2 ounces av. Petrolatum, 16 ounces av. Melt the Wax and the Petrolatum together, and when cooling add the Carbolic Acid, and mix them well together. This is a simple Carbolic Ointment or Salve, useful for all purposes. Other medic- inal agents an- frequently added, as Canada Balsam, or White Pine Turpentine, say one ounce, to make it more stimulating for old sores, etc. ; but the plain Carbolic Salve, as above prepared, meets the general requirement. This is a very popular preparation, and ha- only to be put up attractively to sell. 4096. Golden Ointment. oil of < >riganum a fl.drachms. Oil of Sassafras 2 fl.drachms. Balsam of Fir % fl.ounce. citrine t lintment, \ ounces av. Yellow Wax, 1 ounce av. Petrolatum 10 ounces av. M,lt the solid ingredients together, and when cooling add the oils ami Balsam, mixing them well together. 1104 STANDARD PROPRIETARY REMEDIES. 4097. Healing Ointment. White Pine Turpentine, 1 ounce av. Oil of Rosemary, 2 fl. drachms. Oil of Sassafras, 2 fl drachms. Yellow Wax, 1 ounce av. Petrolatum, 16 ounces av. Mix the solid ingredients together, and when cooling add the Oils. 4098. Itch Ointment. Lac Sulphur, 2 ounces av. Naphthalin, 60 grains. Oil Bergamot, 20 minims. Petrolatum, 6 ounces. Rub the Lac Sulphur to a fine powder and sift it into the melted Petrolatum, stirring them well together, and when nearly cool add the Naphthalin and Oil of Bergamot, stirring them well together until cold. The same may be made without Naphthalin, if desired. Red Precipitate Ointment is also much employed for the itch and other parasitic skin diseases. This is usually made with Red Pre- cipitate 1 ounce, Venice Turpentine 1 ounce, Yellow Wax 1 ounce, Petrolatum 9 ounces. 4099. Menthol Ointment. Menthol, . . . 1 ounce av. Yellow Wax, . . . • 1 ounce av. Petrolatum, 6 ounces av. Melt the Wax and Petrolatum, and when cooling add the Menthol and mix thoroughly. 4100. Pile Ointment. Powdered Nutgalls, 1 ounce av. Powdered Opium, 1 drachm. Powdered Myrrh, 2 drachms. Goulard's Extract, 4 fl.drachms. Yellow Wax, 2 ounces. Petrolatum, 16 ounces. Melt the Wax and Petrolatum, and while cooling add the other ingredients, with constant stirring until cold. STANDARD PROPRIETARY REMEDIES. 1105 4101. Salt Rheum Ointment. Oil of Sassafras, 2 fl. drachms. Oil of Hemlock, 1 fl. drachm. Oil of Rosemary, 1 fl. drachm. Pine Tar, % ounce av. Salicylic Acid, 2 drachms. White Pine Turpentine, 1 ounce. Solution Subacetate of Lead, . . . . l /> fl. ounce. Petrolatum, 16 ounces. Melt the solid ingredients together and while cooling incorporate the Oils, Tar and Solution of Lead, stirring them well together until cold. 4102. Skin Ointment. This ointment is designed for any kind of skin eruption or "Ec- zema" as it is popularly termed. For parasitic diseases, however, the Itch or Tetter Ointment will be more efficacious. Tincture of Benzoin, Compound 2 fl. drachms. Juniper Tar, .... 1 fl. ounce. Salicylic Acid, 2 drachms. Resin, 1 ounce av. Oil of Rosemary, 2 fl. drachms. Carbolic Acid, 1 drachm. Petrolatum, 16 ounces av. Melt the solid ingredients, and while cooling add the liquids. 4103. Tetter Ointment. Carbonate of Lead, 1 ounce av. Alum, in fine powder 1 ounce av. Calomel, 1 ounce av. White Pine Turpentine, 1 ounce av. Salicylic Acid, 2 drachms. Petrolatum, . . 12 ounces av. Melt the Petrolatum and Turpentine together, and when cooling add the other ingredients previously mixed, and stir them together constantly until cold. 4104. Thymol Ointment. Thymol, 1 ounce av. Yellow Wax, 2 ounces av. Petrolatum, 16 ounces av. Melt the Wax and Petrolatum together, and when COOling add the Thymol, stirring them well together. 1106 STANDARD PROPRIETARY REMEDIES. 4105. Veterinary Ointment. Citrine Ointment, 2 ounces av. Oil Sassafras, y 2 fl. ounce. Resin, 1 ounce av. Petrolatum, dark, 16 ounces av. Melt the Petrolatum and Resin together, and while cooling add the Citrine Ointment and Oil of Sassafras. PECTORALS. Pectorals might very properly be classed under Cough Remedies, but as there are a few preparations known more particularly as Pec- torals, they are included under this heading. 4106. Cherry Pectoral. Acetate of Morphine, 6 grains. Tincture of Sanguinaria, 4 fl. drachms. Wine of Ipecac, 6 fl. drachms. Wine of Antimony, 6 fl. drachms. Fluid Extract of Wild Cherry, 2 fl. ounces. Oil Bitter Almond, 5 drops. Hydrocyanic Acid, U. S. P., 1 fl. drachm. Alcohol, 2 fl. ounces. Syrup, sufficient to make 1 pint. Mix, and after standing a few days filter clear. This preparation is quite similar to Ayer's. The dose is 15 drops to 1 teaspoonful. 4107. Pectoral Drops. Bateman's. Tincture of Opium, Camphorated, ... 10 fl. ounces. Tincture of Castor 4 fl. ounces. Tincture of Opium, 1 fl. ounce. Tincture of Cochineal, y 2 fl. ounce. Oil of Anise, 15 drops. Mix them. This is supposed to be the original formula. The Philadelphia College of Pharmacy give the following formula as a substitute : Camphor, Catechu, powdered Opium and Red Saunders Wood, each 2 ounces av., Oil of Anise 4 fl.drachms, proof Spirit 4 gallons. Digest 10 days and filter. STANDARD PROPRIETARY REMEDIES. 1107 4108. Pectoral or Cough Pills. Ipecac, in powder, . 100 grains. Squill, in powder, ...... ... 50 grains. Sulphate of Morphine, 3 grains. Tartar Emetic 6 grains. Extract Hyoscyamus, 100 grains. Make 100 pills. The dose is one or two pills. 4109. Pectoral Tea or Hamburg Tea. Brust- Thee. Althaea Root, cut, 4 ounces. Liquorice Root, cut, 1 ounce. Mullein Leaves, cut, 4 ounces. Senna Leaves, cut, 1 ounce. American Saffron, J4 ounce. Malva Flowers, cut, 3 ounces. Blue Flowers (Asters or Bachelor Button), . % ounce. Fennel Seed, bruised, '2 ounce. Anise Seed, bruised, )? ounce. Granulated Sugar, ) 2 ounce. Mix them thoroughly. This is usually put up in packages of about 2 ounces, a tablespooni'ul being steeped in two or three- cups of boiling Water, and the infusion drank freely for influenza and colds. PILLS, PLASTERS AND POWDERS. So many formulas for pills have been given under other headings that it will be unnei essary to give any more in this department, druggists will be able to selei 1 such as they wish from the formulas already given. The manufacture of spread plasters is seldom attempted exi ept by those who have establishments and machinery Lily adapted for the purpose. There is now bul little sale for sticking salves and plasters, and sufficient formulas for them will be found under the heading "Emplastra." The formulas for powders will be found under other headings, the Condition Powders being the most important. 1108 STANDARD PROPRIETARY REMEDIES. RHEUMATIC REMEDIES. Proprietary remedies for Rheumatism, which are to be taken, are quite salable preparations, and the market is not so overstocked with them as with some other remedies. The following formulae are representative of the various kinds. 4110. Rheumatic Remedy. Salicylate of Sodium, 4 ounces av. Iodide of Potassium, 2 ounces av. Nitrate of Potassium, 3 ounces av. Fluid Extract of Black Cohosh, 4 fl. ounces. Fluid Extract of Colchicum, 4 fl. ounces. Oil of Wintergreen, 3 fl. drachms. Sugar, 1 pound av. Water, 5 pints. Alcohol, 2 pints. Mix the Oil of Wintergreen and the Fluid Extract with the Alco- hol. Dissolve the Salts and the Sugar in the Water, mix the solu- tion and allow to stand over night, then filter clear. This is an excellent remedy, the dose is 1 to 2 teaspoonfuls. 4111. Favorite Rheumatic Remedy. Iodide of Potassium, 1 ounce av. Fluid Extract of Colchicum, 1 fl. ounce. Spirit of Nitre, 3 fl. ounces. Syrup Sarsaparilla, compound 1 pint. Gin or Whisky, 12 fl. ounces. Formulas similar to this are popular, and very good results are usually obtained from their use. The dose is a teaspoonful to a dessertspoonful. 4112. Salicylica Rheumatic Remedy. Salicylic Acid, 8 ounces av. Bicarbonate of Sodium, 5% ounces av. Nitrate of Potassium, 3 ounces av. Tincture of Colchicum Seed, 8 fl.ounces. Oil of Wintergreen, 2 fl. drachms. Syrup, 2 pints. Alcohol, 2 pints. Water, sufficient to make 1 gallon. Mix the Salicylic Acid with 2 pints of Water in a gallon bottle and gradually add the Bicarbonate of Sodium in small portions, at STANDARD PROPRIETARY REMEDIES. 1109 intervals of a few moments, giving time for the effervescence to sub- side before adding more. When all has been dissolved (which will require about 2 hours), add the Alcohol in which the Wimergree n Oil has been dissolved, and then the tincture and Syrup, and lastly the Nitrate of Potassium and sufficient Water to make a gallon ; after standing filter. Dose, a dessertspoonful. 4113. Salol Rheumatic Remedy. Salol, 128 grains. Iodide of Potassium, 256 grains. Bicarbonate of Potassium, 12S grains. Elixir, 1 pint. Mix and dissolve. Dose a dessertspoonful. 4114. Rheumatic Elixir. Iodide of Potassium, 1 ounce av. Salicylate of Sodium, 1 ounce av. Wine of Colchicum Seed 2 ounces av. Elixir, sufficient to make 1 pint. Mix and dissolve. Dose, from a dessertspoonful to a table- spoonful. 4115. Rheumatic Cure. Acetate of Potassium, 2^ ounces av. Wine of Colchicum, 2 ll ounces. Elixir, sufficient to make 1 pint. Mix and dissolve. Dose from a teaspoonful to a tablespoonful. 4116. Rheumatic Bitters — Powder. Colchicum Root, in fine powder, 4 ounces. Black Cohosh Root, in fine powder, ... 4 ounces. Prickly-Asb Hark, in tine powder, .... x /i ounce. Cinnamon Bark, in fine powder jounce. Iodide of Potassium, in fine powder, . . . 1 ounce Nitrate of Potassium, in fine powder, . . . 1 ounce. Mix thoroughly and put up in packages Or boxes of about i ounce. The contents of the package to be .u\i\r<\ to a quarl of gin. 1110 STANDARD PROPRIETARY REMEDIES. 4117. Rheumatic Remedy — Tea. Black Cohosh Root, cut fine, 6 ounces. Colchicum Root, cut fine, . . 4 ounces. Sassafras Bark, cut fine, 2 ounces. Prickly-Ash Bark, cut fine, 1 ounce. Juniper Berries, crushed, 1 ounce. Nitrate of Potassium, in powder, 2 ounces. Mix thoroughly and put up in packages of about 2 ounces, which is sufficient for a quart of liquid medicine. It may be added to a quart of Gin or Diluted Alcohol. SARSAPARILLA COMPOUNDS. Of all proprietary medicines the Sarsaparilla Compounds have the largest sale. They are put up under various names and titles, as alteratives, blood purifiers, blood searchers, blood cleansers, medical discoveries, resolvents, etc., but are' best known and most frequently sold under the name of " Sarsaparilla," although this is considered medicinally the least valuable of the drugs composing the preparation. In the preceding pages many good formulas for Sarsaparilla preparations suitable for putting up will be found under other headings. The following are also given as representative of preparations of this kind found in the market as proprietary medicines. 41 18. Sarsaparilla Compound. With Iodide of Potassium. This is one of the best and most common Sarsaparilla prepara- tions. Sarsaparilla, in No. 30 powder, . Stillingia, in No. 40 powder, . . Burdock Root, in No. 30 powder, Blue Flag Root, in No. 20 powder, Mandrake Root, in No. 50 powder, Senna Leaves, in No. 20 powder, Prickly-Ash Bark, in No. 50 powder Iodide of Potassium, Sarsaparilla Flavoring, . Diluted Alcohol, . . . Sugar, Water, a sufficient quantity to make 8 ounces av. 8 ounces av. 3 ounces av. 1 y* ounces av. 1 V-2 ounces av. 1 % ounces av. H ounce av. 1 ounce av. 1 fl. ounce. 4 pints. 5 1 pounds av. gallon. STANDARD PROPRIETARY REMEDIES. 1111 Mix the drugs, moisten them with 2 pints of Diluted Alcohol and macerate for 24 hours ; transfer to the water-bath percolator, pack moderately, pour upon them 2 pints of Diluted Alcohol and set in a warm place for 24 hours ; then heat moderately, and after one hour begin to percolate adding Water to the drugs after the liquid has ceased to drop and continuing the heat and percolation until five pints are obtained. To this add the Sarsaparilla Flavoring and Iodide of Potassium, and after standing 24 hours filter, adding through the filter enough Water to make 5 pints. In this dissolve the Sugar and add enough Water to make 1 gallon. A larger quantity of Iodide of Potassium may be added if desired. 4119. Concentrated Extract of Sarsaparilla Compound. This formula makes a preparation similar to the stronger Sarsa- parilla compounds that are found in the market, like Ayer's and other similar preparations. Fluid Extract Sarsaparilla, Honduras, . 4 fl. ounces. Fluid Extract Yellow Dock, .... 4 fl. ounces. Fluid Extract Stillingia, 3 fl. drachms. Fluid Extract Mandrake, 2 fl. drachms. Sugar, i>4 ounce. Iodide of Potassium, 100 grains. Iodide of Iron, 10 grains. Alcohol, 4 fl. ounces. Water, sufficient to make 1 pint. Mix, dissolve and filter. The dose is from half t<> a teaspoonful The weaker Sarsaparilla compounds may be made from this by diluting it with 3 parts by measure of Syrup. 4120. Sarsaparilla, Stillingia and Red Clover Extract. Sarsaparilla, 8 ounces av. Stillingia, 8 ounces av. Red Clover Tops, 8 ounces av. Mezereum I'.ark, 1 ounce av. Sassafras Mark i ounce av. [odide of Potassium i <>un make a gallon. Make as directed in the preceding formula. Dose, a teaspoonful to a dessertspoonful. 1112 STANDARD PROPRIETARY REMEDIES. Sarsaparilla Resolvent. A few proprietary preparations found in the market are known as Resolvents. They are mostly compounds of Sarsaparilla with a considerable quantity of Iodide of Potassium or Potassa Alkali, and are known as Cuticura, Resolvent, Ready Resolvent, etc. One sample formula will suffice. Sarsaparilla, Honduras, 8 ounces av. Stillingia, 8 ounces av. Burdock Root, 8 ounces av. Sassafras Bark, 2 ounces av. Blue Flag Root, . .- 2 ounces av. Prickly-Ash Bark, ^ ounce av. Iodide of Potassium, 1 ounce av. Bicarbonate of Potassium, 1 ounce av. Sarsaparilla Flavoring, ^ ounce av. Diluted Alcohol, 6 pints. Sugar, 3 pounds av. Water, sufficient to make a gallon. Grind the drugs to a coarse powder and percolate by water-bath percolation, first with the diluted alcohol, then with enough Water to make 6^ pints of the percolate, add the flavoring, and the salts, and the sugar, and after standing filter. The dose is a dessert- spoonful. 4221. Medical Discovery. Under this title several Alterative and Sarsaparilla compounds have been extensively sold as blood purifiers, etc. The following will suffice for all. Sarsaparilla, Mexican, 8 ounces. Yellow Dock Root, S ounces. Blue Flag Root, 4 ounces. Yellow Parilla, 2 ounces. Leptandra Root, 1 ounce. Sarsaparilla Flavoring, }4 ounce. Iodide of Potassium, 2 ounces. Sugar, 4 pounds. Diluted Alcohol, 6 pints. Water, sufficient to make 1 gallon. Grind the drugs to a coarse powder and percolate by water-bath percolation, first with the Diluted Alcohol and then with Water STANDARD PROPRIETARY REMEDIES. 1113 until 6 pints are obtained, then add the Sarsaparilla Flavoring and Iodide of Potassium and filter, afterwards dissolving the Sugar in the filtrate, and making up the measure with Water to i gallon. The dose is a teaspoonful to a tablespoonful. Iodide of Mercury y 2 ounce may be used instead of Iodide of Potassium. SOOTHING AND TEETHING SYRUPS. The sale for proprietary Soothing Syrups and like preparations is quite extensive, and there are but comparatively few makes on the market. The following formulae make preparations similar to those in use and others quite different from any to be found. 4122. Baby-Soother, or Soothing Syrup. Tincture of Hyoscyamus, 8 fl. ounces. Fluid Extract of Senna, 2 fl. ounces. Oil of Anise, 3 fl. drachms. Chloroform, 30 minims. Alcohol, 10 fl. ounces. Water, 4 pints. Sugar, . 6 pounds av. Dissolve the Oil of Anise and Chloroform in the Alcohol, and mix with the tincture and fluid extract add the Water, fdter clear and dissolve the Sugar in the filtrate by agitation. This is a quiet- ing, slightly laxative Syrup and contains nothing injurious to chil- dren. It may be further improved by adding to it 1 pint of Syrup. Lacto-phosphate of Lime, which supplies to the blood the required nutrition during the critical period <>( dentition. From %. to a teaspoonful may be given at a tins, 4123. Soothing Syrup. Rochelle Salts iy'i ounces. Sulphate of Morphine 6 grains. Extract Jamaica (linger, >2 OUni «■. Essence Of Anise (1 part Oil Of Anise to 1 6 parts Alcohol), 1 ounce. Sugar, 13 ounces. Water, * ounces. Carbonate Magnesium, i drachm. Mix the Extracl Ginger and Essence Anise, and rub them with the Carbonate Magnesium, in a mortar, to a smooth paste ; add the 1114 STANDARD PROPRIETARY REMEDIES. Water a little at a time, and rub thoroughly ; filter, and dissolve the Morphine first, and then the Rochelle Salts in the filtrate ; when dissolved filter, if necessary, and dissolve the Sugar in the liquid by agitation. Dose, % to i teaspoonful. 4124. Quieting Syrup. Lactucarium, 256 grains. Extract Ginger, y 2 ounce. Essence Anise, 1 ounce. Sugar, 13 ounces. Hot Water, 8 ounces. Rochelle Salts, i J /i ounces. Rub the Lactucarium with the Hot Water in a mortar, and add the Rochelle Salts, 'allow to macerate with occasional agitation for twenty-four hours, then add the Ginger and Anise to the Sugar, and shake thoroughly together, and dissolve in the liquid by agitation. When dissolved, strain. Dose, ^ to 1 teaspoonful. 4125. Rhubarb Soothing Syrup. Rhubarb, 8 ounces. Anise Seed, .3 ounces. Jamaica Ginger, 2 ounces. Poppy Leaves, 4 ounces. Bicarbonate Potassium, 2 ounces. Water, q. s., to make 4^ pints. Sugar (avoirdupois weight), 7 pounds. Grind the drugs to a coarse powder. Dissolve the Bicarbonate Potassium in the Water and moisten the drugs with it ; pack in a percolator, and pour the Water upon the drugs ; macerate for two days, and begin the percolation ; percolate until 4)^ pints are ob- tained, adding enough Water through the percolator to make that quantity. Dissolve the Sugar in the percolate by agitation or gentle heat, and strain. Dose, %. to 1 teaspoonful. This is a harmless Soothing Syrup, well suited to neutralize the acid stomach and to correct the bowel difficulties incident to teething. STANDARD PROPRIETARY REMEDIES. 1115 4126. Nutritive Soothing- Syrup. Sulphate of Morphine, 6 grains. Syrup of Lacto-phosphates, compound,. . . 15 ounces. Water, 1 ounce. Dissolve the Morphine in the Water, and add to the Syrup. Dose, Yi to 1 teaspoonful. This is an excellent compound for teething babies. 4127. Malt Soothing Syrup. Sulphate of Morphine, 6 grains. Water, 1 ounce. Compound Svrup of Hvpophosphites, I , . - 1 1 .111 > 1 each, - 1 2 ounces. Liquid Extract Malt, ) Dissolve the Morphine in the Water and mix with the Extract of Malt, then mix the Syrup Hvpophosphites Dose, ^ to 1 teaspoonful. The same remarks apply to this as to No. 4, the addition of Malt being of much service. SALTS. A few preparations in the form of Salts have a good sale as pro- prietary medicines. The following are representative of those found in the market, others will be found under other headings. 4128. Seltzer Aperient. Sulphate of Magnesium dried 2 ounces. Rochelle Salt, dry 2 ounces. Tartaric Acid, dry 6 ounces. Bicarbonate of Sodium 6}4 ounces. Mix them thoroughly and put Up in dry bottles. It is necessary thai the Sulphate of Magnesium (Epsom Salts) should 1).- thoroughly dried by heating on a sand bath in a porce- lain vessel for a considerable time until it has lost its Water of crystallization. The dose is a teaspoonful or two in part of a glass of Water. 1116 STANDARD PROPRIETARY REMEDIES. 4129. Fruit or Grape Salt. Several preparations under various titles as Fruit Salt, Grape Salts, Fruit Saline, Sal Muscatel, etc., are put up as laxatives and restoratives. The following formula will suffice for all : Bicarbonate of Sodium, 6 ounces. Tartaric Acid, 2 ounces. Cream of Tartar, 10 ounces. Rochelle Salt, 4 ounces. Sugar, 1 ounce. Oil Lemon, 30 minims. Oil Orange, 20 minims. Oil Limes, 20 minims. Mix the Oils with a small portion of the Rochelle Salt, and then with the remainder, and incorporate this thoroughly, first with the Cream of Tartar and then with the Bicarbonate of Sodium and put up in dry bottles. 4130. Crab-Orchard Salts. Sulphate of Magnesium, 2 ounces. Sulphate of Sodium, 2 ounces. Cream of Tartar, 2 ounces. Tartaric Acid, 2 ounces. Bicarbonate of Sodium, 2 ounces. Sugar, 4 ounces. Dry the salts and mix them well together and put up in dry bottles. 4131. Carlsbad Salts, Artificial. Chloride of Sodium, 1 ounce. Bicarbonate of Sodium, 3 ounces. Sulphate of Sodium, dried, 10 ounces. Mix them thoroughly and put up in dry bottles. The Sulphate of Sodium must be dried by heating on a sand- bath until its Water of crystallization has evaporated and it is reduced to a dry powder. This may also be prepared by dissolving the salts altogether in water and evaporaring to a granular salt. This is given as a laxative in doses of a teaspoonful in part of a glass of Water. STANDARD PROPRIETARY REMEDIES. 1117 SPECIFICS. A few proprietary medicines are know as Specifics. The name is applied to medicines of various kinds, for asthma, catarrh, dyspepsia, gout, rheumatism, malaria, etc., but is more particularly understood to apply to remedies for Syphilis, and these only will be considered under this heading, as they are not given elsewhere except generally under alteratives, sarsaparillas, etc. 4132. S. S. Specific. Fluid Extract of Stillingia 8 fl. ounces. Fluid Extract of Blue Flag, 2 fl. ounces. Fluid Extract of Prickly-Ash, . . . . 1 fl. ounce. Iodide of Potassium, 1 ounce av. Iodide of Calcium Yil of Turpentine, i fl.drachm. ( lastor ( >il, 6 fl.oui M ix well together. 1124 STANDARD PROPRIETARY REMEDIES 4153. Vermifuge. Oil of Wormseed, .... . . . . 1 fl. ounce. Fluid Extract Pink and Senna, . . . 1 fl. ounce. Glycerine, ... 5 fl. ounces. Essence of Peppermint, y 2 fl. ounce. Mix well together, shake before taking. The usual dose of vermifuge is from one-half to a teaspoonful. 4154. Worm Lozenges. This is by far the most popular form of administering worm medicines, for children will readily take them. The making of worm lozenges is mostly done by manufacturing houses who have apparatus suitable for such work. Santonin is the chief medicinal ingredient ; it is sometimes combined with calomel or other laxative remedies. The following formulas make good worm lozenges, com- fits or tablets. They can be made in the same way as other lozenges : Santonin in fine powder, ....... 50 grains. Powdered Tragacanth, ..,.,. 150 grains. Chocolate, .... 300 grains. Powdered Sugar, . . ....... 700 grains. Rub the Chocolate with a little Water to a stiff paste. Mix the Santonin, Tragacanth and Sugar intimately, and with the addition of Water incorporate them with the Chocolate paste and cut into 100 lozenges. 4155. Worm Lozenges or Tablets. Santonin, in fine powder, 50 grains. Calomel, 5 grains. Carmine, 10 grains. Powdered Tragacanth, 150 grains. Powdered Sugar, 1,000 grains. Mix the Carmine intimately with a portion of the Sugar, add the Santonin and Calomel, then the Tragacanth, and having mixed them thoroughly together make into a mass with Water and cut into 100 lozenges. Other combinations may be made in the same manner. As each lozenge contains }4 grain of Santonin, the usual dose for children would be one or two before meals. STANDARD PROPRIETARY REMEDIES. 1125 4156. Worm Tea-Powder. This was formerly a very popular form of medicine for worms, but has now been superseded by more convenient preparations. Wormseed, in powder, 2 ounces. Pink Root, in powder 6 ounces. Senna, in powder, 6 ounces. Liquorice Root, in powder, 2 ounces. Mix them thoroughly. The dose is a teaspoonful to a dessert- spoonful in half a cup of hot water, sweetened, before meals. 4157. Vermifuge Tea. Pink Root, in coarse powder, 4 ounces. Pomegranate Bark, cut, 4 ounces. Senna Leaves, cut, 4 ounces. Wormseed, 2 ounces. Anise Seed, ground, 2 ounces. Mix thoroughly and put up in packages, of about two ounces. Directions for preparing : Steep the contents of the package in a pint and a half of Water with gentle heat for two hours, then strain off one pint, add to it half a pound of sugar and % pint alcohol. Directions for taking : For children two to three years old a tea- spoonful before meals, three times a day ; three to five years old, two teaspoonfuls ; five to ten years old, a tablespoonful ; ten years and older, a wine-glassful (two tablespoonfuls) before meals. 4158. Tape Worm Remedy. Pomegranate Dark, ground, 3 ounces av. Mali- Fern, ground i ounce av. Senna Leaves, -round 1 ounce av. Kanieela 2 drachms. Mix them well together. ( )ne-lialf of this quantity is to be Steeped in a pint of water and the infusion to he taken in doses of four ounces twenty minutes apart. If not successful in getting the head of the tape worm, the remainder can he prepared and taken in the same manner a week later. Fluid Extracts of the ingredients as above may be mixed in the same proportion and given in the same manner, but arc not consid- ered SO eiiic iciii as the infusion. 1126 STANDARD ^PROPRIETARY REft UNCLASSIFIED PROPRIETARY REMH.DIES. The following preparations were not included in the classes which have been already given. Many more might be included, but the line is already quite extended and is probably sufficient for the uses of the trade. 4159. Phosphorized Cod Liver Oil. Phosphorol. Phosphorus 1 grain. Cod Liver Oil, 24 fl. ounces. Shave the Phosphorus fine and having mixed it with 4 fl. ounces of the Oil, stop tightly in a bottle and heat by water-bath until the Phosphorus is melted, shake well until the Phosphorus is all dis- solved, then add the remainder of the Oil and mix them well to- gether. A dessertspoonful, the usual dose, contains ycto" g ram Phosphorus. 4160. Iodized Cod Liver Oil. Iodine, 16 grains. Cod Liver Oil 16 fl. ounces. Add the Iodine to the Cod Liver Oil contained in a closely stopped bottle, and heat by means of a water-bath until the Iodine is dissolved. A dessertspoonful, the usual dose, contains % grain Iodine. 4161. Iodo-ferrated Cod Liver Oil. Tasteless Iodide of Iron, 64 grains. Cod Liver Oil, 16 fl. ounces. Rub the Tasteless Iodide of Iron to a fine powder and then with the Cod Liver Oil gradually added, until the salt is dissolved as much as it will, then allow to settle and decant the clear portion. The dose is a dessertspoonful. 4162. Hamburger Drops. Socotrine Aloes, in powder, 2 ounces. Myrrh, in powder, % ounce. Cinnamon Bark, in powder, y% ounce. Cloves, in powder 1 drachm. STANDARD PROPRIETARY REMEDIES. 1127 Opium, in powder, i drachm. Saffron, American, 2 drachms. Alcohol, sufficient to make 1 pint. Mix the drugs and macerate first with 12 fl. ounces of Alcohol for one week with frequent agitation and pour off the clear liquid and reserve, then pour on the drugs, 6 flounces more of Alcohol, mace- rate as before and add the product to the reserved liquid. The dose is 10 to 30 drops or more. 4163. Holloway's Pills. As these are much called for, the formula is given. Aloes, ^00 parts. Rhubarb, 40 parts. Black Pepper, 18 parts. Saffron 10 parts. Sulphate of Sodium, dried, 10 parts. To be divided into 3)2 grain pills. 4164. Hunn's Life Drops. Oil of Cajuput 1 fl. ounce. Oil of Anise 1 fl. ounce. Oil of Cloves, 1 fl. ounce. Oil of Peppermint, 1 ll. ounce. Alcohol, 4 bounces. Dissolve the Oils in the Alcohol. This is used as a quick stimu- lant for colic, pain, etc. The dose is 10 to 20 drops on sugar. 4165. Liquid Rennet. 1 inner lining membrane of one calf's stomach, dis- ted off and i hopped. Hydrochloric Acid, 6 fl drachms. Glyi erin 6 fl.oum Water, - iffii ient to make i pint. Mai .rate for two weeks and strain or filter. This is used for dyspeps'a and also in cooking to make curd, with milk. Pepsin prepared from calf's stomach ma) be used instead of the fresh stomachs, but pepsin prepared from pig's, or other, stomachs will not make a curd with milk. The dose is a teaspoonful to a dessertspoonful. 1 128 STANDARD PROPRIETARY REMEDIES. 4166. Listerine. This is a proprietary medicine used as an antiseptic solution, and claimed to contain the essential antiseptic properties of thyme, eucalyptus, baptisia and mentha arvensis, combined with benzoic and boric acids. The following formula will make a good preparation of this kind, but is not claimed to be the exact formulae of the original. Boric Acid 128 grains. Benzoic Acid, 64 grains. Baptisin, 20 grains. Thymol, 20 grains. Eucalyptol, 10 grains. Menthol, ...'.... 10 grains. Oil of Wintergreen, 5 minims. Glycerin, 1 fl. ounce, Alcohol, 2 flounces. Water, sufficient to make 1 pint. Mix the Boric Acid with the Glycerin and Water, add the other ingredients to the Alcohol, and after standing 24 hours, add the aqueous solution to the alcoholic, and after standing filter. 4167. Papine. This is a proprietary preparation of Opium claiming to represent 1 grain of Opium in a fl. drachm. Such a preparation may be made as follows : Deodorized Tincture of Opium (1870), . . 3^ fl. ounces. Elixir, 13 fl.ounces. Mix them. Dose a tablespoonful. 4168. Soda Mint. Bicarbonate of Sodium, . 1 ounce av. Peppermint Water, 1 pint. Aromatic Spirit of Ammonia, 1 fl. drachm. Mix, dissolve and filter. This may be sweetened with 2 ounces of Sugar if desired, but for medicinal effect is usually preferred plain. This is given in doses of a teaspoonful to a tablespoonful, for acid stomach, dyspepsia, etc. STANDARD PROPRIETARY REMEDIES. 1129 4169. Chlorides Solution. A. solution of Chlorides for disinfecting, bleaching, deodorizing, etc., may be prepared and put up as proprietary. Formulas have been already given for such preparations under other headings. The following is, however, given : Chloride of Ammonium, % ounce. Chloride of Calcium, J4 ounce. Chlorinated Lime, 2 ounces. Carbonate of Sodium, 2)4 ounces. Water, sufficient to make 2 pints. Dissolve the Chlorides and Chlorinated Lime in 1 pint of Water and the Carbonate of Sodium in a pint of boiling Water, and pour upon the solution of Chlorides, etc. in a close vessel, stir the con- tents, cover tightly, allow to settle and decant the clear liquid. 4170. Colorless Solution Hydrastine. Hydrastine, White Alkaloid 20 grains. Glycerin, 2 ounces. Diluted Hydrochloric Acid, q. s. to dissolve, Water, sufficient to make 1 pint. Rub the Hydrastine with a portion of the Water and add the Acid drop by drop until it is dissolved, then add the Glycerin and the remainder of the Water. 4171. Stoke's Liniment. Oil of Turpentine, 3 fl. ounces. Oil of Lemon 60 minims. A. etic Auin> e Seeds for half a day with the Water and strain. Mix with the Glycerin. Dis- solve the Oil of Hitter Almonds in the Spirit of Camphor and gradually add to it the Mucilage of Ouince, etc., and mix them thoroughly. 4184. Fragrant Cream.— Ouince Seed 120 grains, Borax, in powder, 60 grains, Hot Water 12 fl.ounces, Glycerin 3 fl.ounces, Cologne 2 fl.ounces. Crush the Quince Seed and macerate with the Hot Water for one hour, stir- 1134 TOILET PREPARATIONS AND PERFUMES. ring frequently, then strain through muslin, without pressure, add the Glycerin and Borax, and then add the translucent solution to the Cologne slowly, shak- ing them well together. One ounce of Bulk Perfume and i ounce of Cologne Spirit may be used instead of the Cologne. This is used for softening the skin, chap, etc. By using double the quantity of Quince Seed a preparation similar to " Frostilla " may be made. 4185. Marshmallow Cream. — Tragacanth, in powder }£ ounce av., Marshmallow Root, cut, l / 2 ounce av., Water 12 fl. ounces, Glycerin 3 fl. ounces, Cologne 2 flounces. Mix the Glycerin with the Water, add the Tragacanth and Mallow to the mixture and agitate frequently for several days, then strain through a muslin strainer, add the Cologne, let stand two or three days and strain again. 4186. Savonia Cream. — White Castile Soap 1 ounce, Tragacanth % ounce, Water 8 fl.ounces, Glycerin 6 fl. ounces, Cologne 2 fl.ounces. Make in the same manner as the preceding. 4187. Blandine. — Take of Albumen (white of egg) 6 ounces, Glycerin 10 ounces, Oil Bitter Almonds 10 drops. Mix the Albumen with the Glycerin, and add the flavor ; pass several times through a muslin strainer to mix well and remove any "lumps." This is a fine liquid preparation for the skin. As the Glycerin is absorbed, a thin coating of Albumen is left on the surface, which protects it from the air. 4188. Amandine. — This is a preparation intended to whiten and soften the skin and prevent chaping, etc. Honey, strained, 2 ounces, White Soft Soap (2908) 1 ounce, Liquor Potassa, 1 fl. drachm, Oil of Sweet Almonds 28 ounces, Oil of Bergamot i}4 drachm, Oil of Bitter Almonds 1% drachm, Oil of Cloves 40 minims, Balsam Peru 40 minims. Rub the honey with the Soft Soap in a mortar add the Liquor Potassa, and when thoroughly mixed gradu- ally add the Almond Oil, with which the other oils have been previously mixed, stirring them thoroughly to form an emulsion. 4189. Shaving Cream.— White Wax, Spermaceti, Almond Oil, each y 2 ounce, Shaving Soap, William's 2 small cakes, Rose Water 2 ounces. Melt the Soap with the Rose Water in a wide mouth bottle. Melt the Wax Sper- maceti and Almond Oil together and add to the warm solution of Soap, beat- ing them all well together into a cream until cool. Another formula is, William's Soap 8 ounces, Almond Oil, Cologne and Glycerine each 1 ounce, Water 8 ounces, made in the same manner. 4190. Shaving Cream for Metal Tubes.— Lard 16 ounces, Spermaceti 1 ounce, Caustic Potassa 2 ounces, Alcohol ]/ 2 ounce, Oil Bitter Almond 20 minims, Water 16 ounces. Melt the Lard and Spermaceti together on a sand-bath. Dissolve the Caustic Potassa in half the Water and gradually add the solution to the melted Lard, etc., with gentle stirring. Dissolve the Oil of • Almond in the Alcohol, mix with the Water and while the Soap is cooling mix it thoroughly. This may be run into metal tubes while warm. TOILET PREPARATIONS AXD PERFUMES. 1135 Face and Toilet Powders, etc. A great variety of Toilet and Face powders are found on the market, some in the form of powder and some in the form of balls or solid blocks or tablets. The following formulas represent the most desirable kinds. 4191. Face Powder — (white). — Oxide of Zinc, English, Hubbuck's 6 ounces, Precipitated Chalk, English 6 ounces, Rice Flour, Bolted 16 ounces, French Chalk, very fine powder, 4 ounces, Orris Root, in very fine powder, 4 ounces, Oil of Santal 60 minims, Oil of Cloves 20 minims. The Orris Root must be reduced to an impalpable powder, and thoroughly mixed with the other powders, the Oils are then to be rubbed with a portion of the powder, and the remaining powder gradually added and thoroughly mixed. The chief trouble usually experienced with Face Powders is to reduce them to the proper fineness. This is especially the case when Orris Root is used, as it is a very refractory substance to reduce to an impalpable powder. To obviate this difficulty, the Extract of Orris (934), such as is used in perfumery; may be used in place of the powdered root. It may be gradually mixed by rubbing it with the powder, and the Alcohol evaporated off by exposing for a few hours in the open air to gentle heat. This should be done before adding the Essential Oils. Flesh. The Flesh-tinted Powders may be prepared from this or any other white powders, by first rubbing a little Carmine to an impalpable powder, mixing it with a portion of the powder, and then gradually incorporating more of the powder until the desired shade is obtained. It requires consider- able care to incorporate the Carmine so that it will not be "streaked," and it may therefore be advisable to add it in the form of a solution, first, with a portion of the powder, and then with enough gradually added to make the desired color. 4192. Swan-Down Face Powder. — Oxide of Zinc, Hubbuck's, 4 ounces, Orris Root, in very fine powder, 1% ounce, French Chalk 4^ ounces. Mix them thoroughly, perfume if desired. 4193. Peerless Face Powder.— French Chalk 2% ounces, Corn Starch 3 ounces, Oxide of Bismuth yi. ounce, Precipitated Chalk 4 ounces. Mix them. 4194. Bloom of Ninon Face Powder. — Precipitated Chalk 4 ounces, Sub-Carbonate of Bismuth 1 ounce, Oxide of Zinc, Hubbuck's, 2%. ounces, Corn Starch 4 ounces. Mix them thoroughly and perfume with Essence of Orris and Rose. This is known also as Saunders Face Powder. 4195. Invisible Face Powder. — French Chalk 4 ounces, Calcined Mag- nesia 1 ounce, Precipitated Chalk 2 ounces, Subcarbonate of Bismuth 1 ounce, Carmine 30 grains. Mix them. 4196. Complexion Powder. — French Chalk 4;^ ounces. Precipitated Chalk 3 oun es, Oxychlo le oi Bismuth [ounce. Mix them. 1136 TOILET PREPARATIONS AND PERFUMES. 4197. Lily White Tablet.— The Lily White tablets and solid cakes and balls that are found in the market consist mainly of Prepared or Precipitated Chalk 4 parts, French Chalk 5 parts, ground together in a mill with water sufficient to make a thick paste, and run into the desired form or cut, or formed while still moist into the required shape. 4198. Rose or Violet Toilet Powder. — The ordinary Toilet or Baby Powder which is used as a drier or dusting after washing, and by barbers after shaving, may be made with Wheat Starch or Arrow Root, in fine powder, 1 pound, Oxide of Zinc or Oxide of Bismuth 4 ounces, Orris Root, in very fine powder, 2>£ ounces. This may be perfumed with Essence of Rose for Rose Powder, or with Essence of Orris for Violet Powder. DENTIFRICES. Dentifrices or cosmetics for the teeth are found in the market in the forms of Tooth Powders, Tablets, Pastes, Washes and liquid saponaceous compounds. They are mostly to be used on a brush, and are put up in various ways to make them attractive and con- venient for use. The following formulae represents the different kinds of preparations which are in use : Tooth Washes and Cosmetics. 4199. Balm of a Thousand Flowers. — This is a liquid dentifrice, also used for softening the skin, shaving, etc. It may be made as follows : White Castile Soap 2 ounces, Honey 4 ounces, Water 12 ounces, Alcohol 4 ounces, Oil of Rose 3 drops, Oil of Wintergreen 10 drops, Oil of Cinnamon 5 drops, Extract of Vanilla y 2 ounce. Dissolve the soap in the water by the aid of heat, add the Honey ; dissolve the Oils in the Alcohol and mix with the solution of Soap, etc. After standing, filter. 4200. Oriental Tooth Wash. — Soap Bark (Ouillaya) 4 ounces, Orris Root 2 ounces, Tannin 30 grains, Cloves 60 grains, Oil Wintergreen 2 drachms, Cologne Spirit enough to make 20 ounces. Grind the drugs to a coarse powder and macerate for seven days in 1 pint of Cologne Spirit; pour off the liquid and put the drugs in a percolator ; pour the liquid upon the drugs and percolate, adding Cologne Spirit in the percolator until 20 ounces of percolate are obtained. Dissolve the Oil of Wintergreen in the percolate, and filter, if necessary. 4201. Saponaceous Tooth Wash. — White Castile Soap 1 ounce, Oil Cloves, Oil Cinnamon each 10 minims, Oil Wintergreen 15 minims, Oil Peppermint 20 minims, Hot Water 4 ounces, Alcohol or Cologne Spirit 10 ounces, Glycerin 2 ounces. Cut the Soap in thin shavings, and dissolve in the Hot Water; dissolve the Oils in the Alcohol, add the Solution of Soap and Glycerin, and color with Cochineal or Caramel, or both ; filter, add a little Powdered Charcoal in the filter. TOILET PREPARATIONS AND PERFUMES, 1137 4202. Eau Angelique.— Angelica Root, true, yi ounce, Red Rose Leaves 2 drachms, Cloves 90 grains, Nutmeg, Cinnamon, each, 60 grains, Extract Vanilla yi ounce, Oil Peppermint 30 minims, Oil Wintergreen 20 minims, Cologne Spirit 14 ounces, Glycerin 2 ounces, Cochineal 8 grains. Grind the drugs to a fine powder and macerate for seven days with the mixed Glycerin and Cologne Spirit ; pour off the liquid and put the drugs in a per- colator ; pour the liquid upon the drugs and percolate, adding enough Cologne Spirit through the percolator to make 1 pint. Dissolve the Oils in 2 drachms of Cologne Spirit and mix with the liquid ; then add the Extract Vanilla and filter, adding a little Powdered Charcoal in the filter. 4203. Balsamic Tooth Wash.— Compound Tincture of Benzoin, Tinc- ture Tolu, Tincture Myrrh, each yi ounce, White Castile Soap 1 ounce, Hot Water 10 ounces, Glycerin 2 ounces, Cologne Spirit 3 ounces, Oil Pepper- mint 40 minims, Oil Wintergreen 20 minims, Oil Cloves 10 minims. Mix the Tinctures and the Cologne Spirit, and dissolve the Oils in the mixture. Cut the Soap in fine shavings, and dissolve in the Hot Water ; add the Glycerin to this solution. Add the saponaceous solution very gradually to the solution of Oils and Balsams, allow to stand twenty-four hours, shaking occasionally, then filter, adding a little Powdered Charcoal to the filter. The saponaceous solution can be best added to the balsamic solution by putting a cork in a funnel so that it will be added drop by drop. The solution of soap must always be added to the balsamic solution. 4204. Almond Tooth Cream. — Tincture Myrrh, Tincture Tolu, each yi ounce, Oil Bitter Almonds 20 minims, Borax, powdered, yi ounce, Glycerin 2 ounces, Hot Water 13 ounces. Mix the Tinctures, and dissolve in the mixture the Oil of Bitter Almonds, dissolve the Borax in the Hot Water and add the Glycerin, add the solution of Borax very gradually (by dropping as directed in the previous formulae) to the Tinctures, etc. 4205. Carbolated Tooth Wash.— Carbolic Acid 20 grains, Alcohol 1 drachm, Eau Angelique 1 pint, dissolve the Carbolic Acid in the Alcohol and add the Eau Angelique. Carbolic Acid may be added to any of the other Tooth Washes, in the same proportion as above. It makes a valuable addition in many cases, as it destroys the odor of decayed teeth and offensive breath. 4206. Arnica Tooth Wash.— Arnica Flowers 1 ounce, Gum Myrrh yi ounce, Cloves 60 grains, Cinnamon 60 grains, Oil Peppermint 40 minims, Cologne Spirit enough to make 1 pint, grind the drugs to a fine powder and percolate with the Cologne Spirit until 1 pint is obtained, and add the Oil of Peppermint, filter if necessary. 4207. " Sozodont."— This is a proprietary Dentifrice, a similar prepara- tion may be made with White Castile Soap 1 % ounce av., Glycerin 4 fl.ounces, Cologne Spirit 6 fl.ounces, Water 6 fl.ounces, I »il Peppermint 20 minims, ( >il Wintergreen 30 minims, Oil Cloves, 10 minims, Extract Vanilla )i ounce, cut the Soap in line shavings and dissolve it in the water by the aid of heat, 1138 TOILET PREPARATIONS AND PERFUMES. then add the Glycerin and Extract Vanilla, dissolve the Oils in the Alcohol and add, and after standing filter. Tooth Pastes. Tooth pastes are favorite dentifrices, made up in the form of a soft mass and usually put up in flat earthen jars. 4208. Cherry Tooth Paste.— Precipitated Chalk 8 ounces, Powdered Orris Root 8 ounces, Powdered Areca Nut 2 ounces, Powdered Cuttle Bone 2 ounces, Powdered Quillaya Bark 1 ounce, Borax, in powder, 1 ounce, Carmine , in fine powder, or solution of Carmine, a sufficient quantity Oil of Cloves, Oil of Nutmeg-, each 40 minims, Oil of Bitter Almond 30 minims, Oil of Rose 10 minims, Glycerin, Honey and Mucilage Acacia, equal quantities, each a sufficient quantity to make into a mass, mix the powders first and color with the Carmine or Carmine solution, then make into a mass. 4209. Saponaceous Tooth Paste.— Precipitated Chalk 4 ounces, Pow- dered Orris Root 4 ounces, White Castile Soap 1 ounce, Powdered Borax 1 ounce, Powdered Myrrh y z ounce, Honey and Glycerin, equal parts, suffici- ent to make a paste. This may be perfumed with Wintergreen, Cassia or •other flavors, and colored with Carmine or Rose Pink, if desired. 4210. Odontine Paste. — French Chalk 8 ounces, Soap, in powder, 4 ounces, Sugar 4 ounces, Gum Arabic, in powder, y 2 ounce, Peppermint Oil, Winter- green Oil, each 1 drachm, Glycerin and Honey, sufficient to make a mass. This may be colored if desired. 421 1. Charcoal Tooth Paste. — A Charcoal Tooth Paste may be made by using 4 ounces of Charcoal, in fine powder, instead of the Soap, in the foregoing formula. 4212. Tooth Paste for Metal Tubes. — A Tooth Paste for putting up in metal tubes may be made from any of the foregoing formulas by making them much thinner with the Glycerin and Honey than when they are to be put up in jars or pots. Tooth Powders. Tooth Powders are the most frequently sold of any of the denti- frices, probably because they are better known and are furnished at a less price; a great variety are found in the market. The following formulae make preparations similar to a few of the best. 4213. Tooth Powder. — General formula. — Precipitated Chalk 8 ounces, Powdered Cuttle Bone 4 ounces, Orris Root, in powder, 3 ounces, Powdered Borax 1 ounce, Oil of Cloves 10 minims, Oil of Wintergreen 2 fl.drachms. Carmine solution a sufficient quantity, mix the powders and with a small por lion incorporate the Oils and sufficient of the Carmine solution to color the TOILET PREPARATION'S AND PERFUMES. 1139 batch, making a moist powder, to this gradually add the remainder of the powder, rubbing the mixture well together until they are thoroughly mixed and of uniform color and flavor. This may be flavored with other flavoring oils in place of those mentioned, as desired, giving it an entirely different flavor. Various substances may be added to this powder, changing it in appearance, flavor, etc., but it is essentially the basis of all the other powders and may be kept in stock for mixing other substances, as Powdered Pumice Stone or Marble Dust may be used instead of Powdered Cuttle Bone, but the latter is generally preferable. 4214. Carbolic Tooth Powder.— Mix Y 2 ounce of Carbolic Acid with 20 ounces of the foregoing, by rubbing it first with a small portion of the powder and then incorporating with the remainder. 4215. Cinchona Tooth Powder.— Add 2 ounces of powdered Cinchona Bark and 1 ounce of -powdered Myrrh to 20 ounces of the general Tooth Powder (4213). 4216. Camphorated Tooth Powder. — Mix Camphor in fine powder 1 ounce with 20 ounces of the general Tooth Powder (4213), and when thor- oughly mixed pass through a fine sieve. 4217. Quinine Tooth Powder.— Mix Sulphate of Quinine % ounce with" 20 ounces of the general Tooth Powder (4213). 4218. Rose Tooth Powder. — Precipitated Chalk 8 ounces, Powdered Orris Root 4 ounces, Powdered Cuttle Bone 4 ounces, Carmine in fine powder 2 drachms, or sufficient to color, Oil of Rose 30 minims, Oil of Santal Wood 5 minims, Oil Cassia 5 minims, mix them well together as directed in the general formula. 4219. Saponaceous Tooth Powder.— Precipitated Chalk 8 ounces, Pow- dered Cuttle Bone 4 ounces, Powdered White Soap 4 ounces, Oil of Winter- green 2 drachms, Oil of Calamus 10 minims, mix them well together. It is needless to give further formulas for tooth powders, as an infinite variety may be made in the same general manner as has been described in the foregoing, it being only necessary to change the flavor, or color, and add such other antiseptic or other ingredients as may be desired. 4220. Tooth Tablets. — These are simply tooth powders put up in the form of cakes or squares, and may be made as follows: Powdered Cuttle Bone or Pumice Stone 4 ounces, Orris Root, in powder, 4 ounces, Carbonate of Magnesium 4 ounces, White Castile Soap 4 ounces, Gum Arabic, in fine powder, 1 ounce, Water 6 ounces, Essence of Wintergreen 2 ounces. Beat the Castile Soap and the Gum Arabic with the water and Essence of Winter- green, and having mixed the other powders, gradually incorporate them widi the mixture by working ill a mortar the same as a pill or lozenge mass. Then roll out and cut out or mark as desired into squares, and dry them with gentle heat. 1140 TOILET PREPARATIONS AND PERFUMES. Mouth Waters. In this connection it is proper to give a few .ormulas for Mouth Waters, which are used for rinsing the mouth and teeth, pre- venting bad breath, etc. 4221. Eau de Botot or Mouth Water. — Anise Seed 10 ounces, Ceylon Cinnamon 2% ounces, Cloves 75 grains, Cochineal y 2 ounce, Oil of Pepper- mint l /z ounce, Alcohol sufficient to make 20 fl.ounces, grind the drugs and macerate with the alcohol, then percolate until 20 ounces have passed and dissolve the Oil of Peppermint in the percolate. This may be more readily made with Oil of Anise % ounce, Oil of Cinnamon 1 drachm, Oil Pepper- mint x / 2 ounce, Oil Cloves, 10 minims, dissolved in Alcohol 19 fl.ounces. A teaspoonful of this is poured into half a glass of Warm Water for rinsing the mouth and teeth. It may be applied to the teeth also with a brush, simply to clean them. 4222. Salicylic Mouth Water.— Salicylic Acid 20 grains, Oil of Pepper- mint 10 drops, Oil of Wintergreen 20 drops, Alcohol 2 fl.ounces, Orange Flower Water, Distilled Water, each, 2^ fl.ounces, mix the Oils and Acid with the Alcohol and add the Waters. This is to be diluted with 2 to 4 parts of Water when used. 4223. Violet Mouth Water.— Extract of Orris Root (934) 8 ounces, Essence of Rose (920) 8 ounces, Oil Bitter Almonds 5 drops, Alcohol 8 ounces, mix them. Use 1 teaspoonful in half a glass of water for rinsing the mouth, etc. HAIR PREPARATIONS. Preparations for the Hair are put up by most all druggists, and a great variety of Dyes, Restoratives, Tonics, Pomades, Cosmetics, Oils, etc., are found in the market. The formulae for Dyes, Re- storatives and Tonics have already been given in the Standard Remedies Department, and the formulas which follow will be more especially devoted to such as are classed with Toilet Preparations. Depilatories. Depilatories are preparations designed to remove superfluous hair, by killing its roots. They are but little used. 4224. Depilatory Paste.— Freshly-slacked Lime 1 ounce, Starch in fine powder 2 drachms, Glycerin 2 ounces, Water y z ounce ; heat the Starch with the Glycerin on a sand-bath until it is gelatinized ; then mix the Lime with the Water and stir with the paste until thoroughly mixed. The hair is to be shaved off close, this is then to be applied and left on for only a few moments TOILET PREPARATIONS AXD PERFUMES. 1141 {3 to 5 minutes), then removed and the part dressed with cream or soft ointment. 4225. Depilatory Powder. — Arsenic 1 part, Quick Lime 8 parts, well mixed together ; when used this is to be mixed with Glycerite of Starch, or Soft Soap ; it should be freshly made when wanted. As this is quite poisonous as well as caustic it should be handled with caution. 4226. Depilatory Liquid. — Quicklime, in powder, 1 ounce, Carbonate of Potassium 1 ounce, Sugar 2 ounces, Water 4 ounces, boil them together and after standing decant. The Caustic Liquid may be applied as it is or mixed with starch paste. Hair Dyes. Formulas for Hair Dyes will be found on pages 1079, 1080; but two more are appended' here. 4227. Bismuth Hair Dye.— Trisnitrate of Bismuth 1 ounce aw, Glycer- ine 3'< flounces, dissolve the Bismuth in the Glycerine. When desired to use mix the Dye with an equal quantity of Water and apply as usual. 4228. Vanadium Hair Dye.— This is applied with two preparations in the same manner as the Nitrate of Silver Dye 4039, using the same mordant, and then apply the Vanadium solution in the same manner as the Silver Dye. The Vanadium Solution is made with Vanadate of Ammonium 10 grains, dissolved in Water 4 ounces. Hair Oils, Etc. These are liquid preparations intended as a dressing for the hair to keep it soft and glossy, clean the scalp, etc. A great variety of such preparations may be made, but a few formulas only will be necessary; for, with a good base, the perfumes may be varied to suit the taste. The following bases may be used : 4229. Castor Oil Base for Hair Oil.— Castor Oil 12 (bounces, Alcohol 5 flounces. Mix them. As Castor Oil mixes in all preparations with Alco- hol this may be made thinner if desired by using a larger proportion of Alcohol. 4230. Other Hair Oil Bases.— Oil of Benne, Oil of Almond, Mustard Seed oil. Oil of Cotton Seed, refined, Lard OH. Salad Oil, Hickory Nut Oil a)i tine a red color to Oils as this. The Oils may be heated or macerated cold, but it requires longer if 1142 TOILET PREPARATIONS AND PERFUMES. prepared cold. Other colors for Hair Oils are seldom required, but they can be colored orange or yellow with Anatto, or green with fresh lawn grass. 4232. Walnut Hair Oil.— As a sample of Hair Oils that may be made by macerating substances of various kinds in oils the following is given : Crush 2 ounces of fresh green Walnut shells with % ounce of powdered Alum to a smooth paste ; digest with 10 ounces of White Neutral Paraffin Oil or any bland Vegetable Oil, as Cotton Seed or other oil, until all vapor has been driven off, then strain and perfume as desired. Fresh Violet Flow- ers, Rose or Orris or other odorous substances, may be macerated with Oil in a similar manner. Perfumes for Hair Oils. Hair Oils may be perfumed as desired with perfuming Oils or mixtures of Oils. The following mixtures for general use are recommended: 4233. Rose Oil Perfume, cheap.— Oil of Bergamot 4 ounces, Oil of Citronella 1 ounce, Oil of Cassia or Cinnamon 3 drachms, Oil of Cloves >£ drachm. Mix them. Of this, from 3 to 6 drachms or more may be used for each pint of Oil. If finer perfumes are desired without regard to expense, from 1 to 3 ounces of Bulk Perfume of any odor may be used in place of an equal quantity of Alcohol in the Castor Oil Base, or the following combina- tions of Fatty Perfuming Oils, etc., may be used to mix with any of the other Hair Oil bases. The fatty Oils mentioned in the formulas are made by mace- rating the fresh flowers in Almond or Olive Oil. They are imported and may be obtained of New- York jobbing houses. These perfumes can also be used for fine pomades or stick cosmetics. 4234. Fine Rose Oil Perfume. — Oil or Otto of Rose 2 parts, Oil of Rose Geranium 4 parts, Oil of Patchouli 1 part, Oil of Jasmine, fatty, 10 parts, Oil of Tuberose, fatty, 10 parts, Oil of Violet, fatty, 5 parts. Mix them. This may be used as is necessary to perfume the Oil, from 2 drachms to 1 ounce being used to each pint of Oil. 4235. Fine Orange Flower Perfume.— Oil of Neroli, Bigarade, 1 part, Oil of Neroli, Petit Grain, Oil of Jasmine, fatty, 10 parts. Mix them. This may be used the same as the foregoing. 4236. Hang Hang Perfume. — Oil of Hang Hang 1 part, Oil of Tuberose, fatty, 10 parts, Oil of Violet, fatty, 5 parts. Mix them. This maybe used the same as the foregoing. Other combinations may be made in the same manner. Hair Growers. For promoting the growth of the hair many preparations of an oily nature are used. Several such preparations are noticed under TOILET PREPARATIONS AND PERFUMES. 1143 Hair Tonics ; the following are added in this department. These are particularly used for thin or falling hair, baldness, etc. 4237. Hair Grower. — Neutral Paraffin Oil or Cotton Seed Oil 1 pint, Cantharides, in coarse powder, 60 grains, Alkanet Root, in coarse powder, Yz ounce, Oil of Cinnamon 5 minims, Oil of Lemon 30 minims, Oil of Citro- nella 10 minims, Oil of Bergamot 60 minims. Enclose the Cantharides and Alkanet in a coarse muslin bag and digest in the Oil by the aid of a water- bath at a moderate heat for 1 2 hours, occasionally squeezing the bag, and then, when cool, add the perfuming oils. 4238. Bay Hair Grower.— Castor Oil 10 ounces av., Tincture of Can- tharides (1880) 1 fl. ounce, Cologne Spirit 5 flounces, Oil of Bay Leaves 20 minims, Oil of Pimento 5 minims, Oil of Bergamot 30 minims. Mix them. This may be colored red if desired with Tincture of Alkanet. 4239. Cocoaine or Cocoa Cream. — Cocoanut Oil 1 ounce, Castor Oil 8 ounces, Cologne Spirit 7 ounces, Oil of Bergamot 1 drachm, Oil of Lemon y 2 drachm. Melt the Cocoanut Oil by gentle heat and add it to the Castor Oil previously warmed, add the Cologne Spirit and, when cool, the flavoring Oils. 4240. Tricophorus. — Castor Oil 8 ounces, Alcohol 8 ounces, Oil Berga- mot \]/z drachms, Tincture Cantharides (1880) 2 drachms, Tincture Alkanet, sufficient to color a light red. Mix. 4241. Hair Grower Pomade.— Petrolatum 1 pound, Tincture of Can- tharides \% ounce, Oil of Cinnamon 10 minims, Oil of Bergamot 60 minims, Oil of Citronella 20 minims, Oil of Cloves 5 minims. Melt the Petrolatum, add the tincture, and while cooling add the oils. Hair Lotions. Hair Lotions differ from Hair Oils in containing but little or no oil. They arc applied more freely to the hair and intended to pro- mote its growth, and give it a gloss or luster, also to clean the scalp and remove dandruff, eruptions, etc. 4242. Almond Hair Lotion.— Cologne 4 ounces, Glycerin 1 ounce, Water of Ammonia y 2 ounce, Bitter Almond or Cherry Laurel Water 4 ounces. Mix them. 4243. Bay Hair Lotion.— Make the same as the foregoing, only use Bay Rum instead of Cologne. 4244. Rose Hair Lotion.— Make the same as the first mentioned, but use Rose Water instead of Almond Water. Many others may be made in the same manner. 4245. Stimulating Hair Lotion.— For thin hair, baldness, etc., Tincture of Cantharides 1 [880) 2 drachms, Acetic Ether 2 drachms, Glycerin 2 ounces, Bay Rum 6 ounces. Mix them. Cologne diluted with an equal quantity of Water may be used instead of Bay Rum. 1144 TOILET PREPARATIONS AND PERFUMES. 4246. Bay Rum. — A great many formulas for Bay Rum have been pub- lished, but we have seen no reason to change the formula which we published many years ago, which quite closely imitates the imported distilled Bay Rum, and gives excellent satisfaction. It was as follows : Oil of Bay Leaves 2 fl. drachms, Oil of Bergamot 30 minims, Oil of Pimenta 15 minims, Acetic Ether 15 minims. Caustic Soda, or concentrated Lye, 2 drachms, Cologne Spirit yA pints, Water 4^ pints. Grass-green coloring, sufficient. Mix the oils and dissolve them in the Cologne Spirit, dissolve the Caustic Soda in the Water and gradually add the solution to the Alcoholic solution of the oils, then add the Acetic Ether and enough of the green coloring to give the de- sired color, and after standing a few days filter through a glass funnel without using a filter rack or any metallic substance. 4247. Shampoo Liquids.— Two kinds of Shampoo Liquids are used, the " wet " and the "dry." the former being intended to be used with a quantity of Water to wash the head and the other to be applied in small quantities and the hair rubbed until nearly dry. Of the former the two formulas are given. 4248. Barbers' Shampoo.— Carbonate of Potassium (Salts of Tartar) 90 grains, Water of Ammonia 3 fl. ounces, Cologne 2 flounces, Water, sufficient to make 2 pints. Mix and dissolve. 4249. Clifford's Shampoo Compound. — Borax 1 2 ounces, Salts of Tartar 4 ounces. Mix and dissolve 1 ounce of the mixture in 1 pint of Water when wanted for use. 4250. Dry Shampoo. — Cologne 1 ounce, Alcohol 2 ounces, Water of Ammonia 3 ounces, Water 1 2 ounces. Mix them. This is applied and the hair rubbed until the lather first formed has dried. 4251. Sea Foam.— Bay Rum 3 n.ounces, Water of Ammonia 3 fl.ounces, Water 10 fl.ounces. Mix them. 4252. Quillaya Sea Foam.— Tincture of Quillaya 2 ounces, Cologne or Bay Rum 2 ounces, Water 1 2 ounces. Mix them. This does away with the odor of Ammonia, which is disagreeable to many. Pomades. Pomades for the hair are fatty preparations of the consistence of ointments. They were formerly made of beef marrow, suet, washed lard, or a mixture of fats, generally perfumed and colored, but were quite liable to spoil or become rancid by standing. Since the intro- duction of Petrolatum it has, in this country, taken the place of other fats as a basis for pomades, as it is of about the right consistence, and never becomes rancid nor deteriorates. It is therefore directed in the following formulas, but if preferred, the purified suet directed for making stick pomades (4256) may be used as a base. 4253. Barbers' Pomade.— Petrolatum 16 ounces, Oil of Bergamot 60 minims, Oil of Citronella 20 minims, Oil of Cassia 10 minims, Oil of Cloves 5 TOILET PREPARATIONS AND PERFUMES. 1145 minims. Melt the petrolatum and while cooling, but still liquid, add the oils and mix thoroughly. If finer perfume is desired without regard to expense the fine perfumes given under Hair Oils may be used. 4254. Fine Pomades. — By mixing equal parts of Petrolatum with various Flower Pomades No. 24, and, if necessary, adding additional perfume, a great variety of Fine Pomades may be made, as Acacia or Cassia Pomade, Rose Pomade, Orange Flower Pomade, Violet Pomade, etc. They may also be made by mixing Petrolatum with Purified Suet (4256), equal parts, and scent- ing with fine perfuming Oils as directed for Stick Pomades. It is unneces- sary to give detailed formulas. 4255. — Pomade Hongroise or Moustache Wax.— White Wax 1 ounce, Powdered Castile Soap x /z ounce, Gum Arabic, powdered, yi ounce, Rose Water 1 ounce, Oil of Bergamot 30 minims, Oil of Thyme 3 drops. Melt the Gum Arabic and the Soap in the Rose Water by gentle heat, then, having previ- ously melted the Wax, add it gradually to the mixture, stirring them con- stantly ; while cooling, add the perfume. It is usually put up in jars or pots. Stick Pomades or Cosmetics. These are pomades of much firmer consistence than the foregoing, containing considerable wax, and run in sticks. They are used for the moustache and whiskers, and for making the hair lay where it is wanted. 4256. Stick Cosmetic Base.— Take 10 pounds of fresh Beef Suet, cut it in small pieces, pound it in a mortar and wash it thoroughly several times in pure cold Water. Then put over the fire and slowly " try it out," not allow- ing it to come to a boil (as that develops the disagreeable animal odor), add to it when melted 2 x / 2 drachms powdered Alum and about the same amount of Salt, then let it come to a simmer, remove the scum that rises, and strain through a fine wire or muslin strainer, into a deep dish partly filled with hot Water. Allow it to stand 2 or 3 hours, that all impure matter may settle, then remove from the dish, melt and mix 1 ounce powdered Gum Benzoin, and y z pint Rose Water, bring to a boil and simmer for a few minutes, skimming off all that rises to the top, add to it x / 2 gallon boiling water, agitate and stir thoroughly and at last pour off into a shallow pan to cool. This makes the same kind of purified grease that is used in making perfumed Pomades. It will keep for any length of time sweet and pure, without be- coming rancid, and is suited well for making any of the harder kinds of Pomades, Cosmetiques, etc. To make the Stick Pomade; take of the Purified Suet thus prepared m 1 . Ounces, White Wax or Paraffin l>£ ounce. Perfume as desired. This is sufficient to make 1 dozen 1 ounce sticks of Pomade, which in. i\ be made l'\ running in suitable moulds. The base may be perfumed with the mixtures of perfuming oils as given 1 140 TOILET PREPARATIONS AND PERFUMES. under hair oils, or as follows : The quantity of perfuming oils stated being for 12 ounces of the base. This may be variously perfumed with other in- gredients, or colored brown with umber, black with ivory black, etc. 4257. Almond Cosmetic— 30 minims Essential Oil of Almonds. 4258. Bay Cosmetic— 30 minims Oil of Bay. 4259. Cassia Cosmetic. — 30 minims Oil of Cassia. 4260. Orange Flower Cosmetic— 20 minims Oil of Neroli. 4261. Rose Geranium Cosmetic— 30 minims Oil Rose Geranium. 4262. Santalina Cosmetic— 30 minims Santal Wood Oil, 5 drops Oil Rose. 4263. Verbena Cosmetic— 20 minims Oil Lemon Grass. 4264. White Rose Cosmetic— 10 minims Oil Rose, 3 minims Oil Patchouly. 4265. Ylang Ylang Cosmetic. — 10 minims Oil Ylang Ylang, 3 minims Oil Rose. Hair Powders. For powdering the hair white ordinary powdered starch scented with some kind of bulk perfume is generally used. The perfume may be rubbed with a small quantity of the powder first and then with the remainder gradually added. Silver powder is made from mica, coarsely ground, and gold pow- der from gold colored mica or Tinsel ground or finely cut. COSMETIC ICES AND JELLIES. The most familiar preparation of this kind is Camphor Ice, which is considerably used for sun-burn, tan, chap, chafe, etc. Cold cream is a softer preparation much used for the same purpose. Formulas for both of these have been given under other headings (3709), (4094), and a few only will be given here. 4266. Camphor Ice with Glycerin.— Paraffin or White Wax 4 ounces, White Petrolatum or Washed Lard 1 2 ounces, Camphor 3 ounces, Glycerin 3 ounces, Oil of Bitter Almond 20 minims, Oil of Rose 5 minims, Oil of Cloves 5 minims. Melt the Paraffin and Petrolatum together and remove from the fire, add the Camphor in powder and keep warm until the Camphor is dis- solved, then strain, and while cooling add the Glycerin and Perfuming Oils, beating them well together until it is cool enough to set, when run into cold moulds or a flat pan on ice. It may then be cut up as desired. 4267. Carbolated Camphor Ice. — This may be made by adding 2 ounces of Carbolic Acid to the ingredients of the formula 4094. TOILET PREPARATIONS AND PERFUMES. 1147 4268. Carbolated Camphor Ice with Glycerin.— This may be made by adding 1 ounce of Carbolic Acid to the ingredients of the formula for Cam- phor Ice with Glycerin (4266). 4269. Glycerin, Honey or Jelly. — Solidified Glycerin. — Transparent Soap 4 ounces, Water 6 ounces, Glycerin 12 ounces, Oil Bergamot 20 minims, Oil Cloves 10 minims, Oil Bitter Almonds 5 minims. Cut the Soap in thin shavings and dissolve in an evaporating dish with the Water, when dissolved add the Glycerin and boil for one hour or until the vapor of Water no longer rises, and the liquid measures only 1 pint, when nearly cool stir in the essen- tial oils and pour into a shallow pan or boxes designed for the preparation ; the perfume may be varied to suit, by using other combinations. This makes transparent Jelly. 4270. Glycerin Jelly.— Another method of making this is as follows : White Castile Soap, in powder, 140 parts, Pure Glycerin 210 parts, Oil of Almonds, expressed, 1260 parts for winter use, or 1680 parts for summer use, Oil of Bergamot 8 parts, Oil of Rose 2 parts, Oil of Lavender 4 parts, mix the powdered Soap and the Glycerin in a Mortar, then add the Oil of Almonds and incorporate it by triturating rapidly and add the perfume. This Jelly is not transparent. 4271. Camphorated Glycerin Honey or Jelly. — This may be made by adding %. ounce of Powdered Camphor to the Glycerin Honey while warm. 4272. Carbolated Glycerin Honey.— This may be prepared by adding Carbolic Acid % ounce to the Glycerin Honey while warm, the same may also be added to the Camphorated Glycerin Honey if desired. 4273. Glycerine Ice.— Gelatine 2 ounces, Water 6 ounces, Glycerin 14 ounces, perfuming Oils to suit. Dissolve the Gelatin in the Water by the heat of a water- bath, add the Glycerin previously heated, boil until only 1 pint remains and strain, while cooling incorporate the perfumes, and pour into shallow tins, this may be colored red or other color if desired. It resembles Ice. To apply it the skin should first be moistened with Water and the cake rubbed over it. 4274. Glycerine Jelly. — Gelatin 1 ounce, Glycerin 1 pint, Boric Acid, in fine powder, 2 drachms, Water 1 pint, Bulk Perfume 1 or 2 ounces. Soak the Gelatin in the Water until soft, then heat until dissolved, add the Glycerin and Boric Acid and strain while cooling, add the perfume and mix thoroughly, this is a thin or soft Jelly and should be put up in pots or jars. It is an excel- lent preparation for chap, chafe and roughness of the skin. 4275. Arnica Jelly. — This may be made by adding 4 fl. ounces of Tincture of Arnica to the Solution of ( u-latin, and boiling the solution until only 1 pint remains, then adding the Glycerin, etc., as before. The firm Arnica Jelly may be made by adding Tincture Arnica 2 ounces, to each pint of any of the former preparations before adding the Glycerin, etc., other substances may be combined with the Jellies in the same manner. 1148 TOILET PREPARATIONS AND PERFUMES. LOTIONS. Lotions are intended to whiten and soften the skin, remove pimples, tan, freckles, sunburn, etc. The milks are also included under this heading, as they are employed for similar purposes. 4276. Moth and Freckle Lotion.— Bichloride of Mercury 60 grains, Chloride of Ammonium 240 grains, Alcohol 3 flounces, Rose or Orange Flower Water 3 fl. ounces, Water 10 flounces. Rub the corrosive sublimate to a fine powder and dissolve it in the Alcohol, dissolve the Chloride of Ammo- nium in the Water, add the Rose or Orange Flower Water and mix with the Alcoholic solution, after standing a day or two, filter. This may be applied once or twice a day with a soft sponge or linen cloth and will quickly remove moth or freckles, tan, etc. 4277. Anti-Freckle Lotion.— Bichloride of Mercury 12 grains, Hydro- chloric Acid 3 fl. drachms, Bitter Almonds i l / 2 ounces, Glycerin 1 ounce, Tincture Benzoin 2 drachms, Orange Flower Water sufficient to make 1 pint. Dissolve the Bichloride of Mercury in 3 ounces of the Orange Flower Water, add the Hydrochloric Acid and set aside. Blanch the Almonds and bruise them to a paste in a mortar with the Glycerin and add sufficient Orange Flower Water to make about 12 ounces of Cream or Milk of Almonds, add to this the Tincture of Benzoin, drop by drop, rubbing them well together, then add the solution of Bichloride of Mercury, and enough Orange Flower Water to make a pint and strain the whole forcibly through a cheese cloth strainer to remove the coarser particles of Almond. 4278. Freckle Lotion. — Sulpho-Carbolate of Zinc % ounce av., Glycerin 3 ounces av., Alcohol 2 fl. ounces, Orange Flower Water 3 fl. ounces, Rose Water sufficient to make a pint. Mix, dissolve and filter. 4279. Face Lotion.— Bitter Almonds, Sweet Almonds, each, 1 ounce, Oil of Almonds 1 ounce, Spermaceti l / z ounce, Borax, in powder, % ounce, Glycerin 4 ounces, Rose or Orange Flower Water sufficient to make a pint. Blanch the Almonds and reduce them to a uniform paste, by beating in a mortar and then rubbing with the Glycerin. Rub the Spermaceti in another mortar previously warmed with the Oil of Almonds, and beat until dissolved. Dissolve the Borax in half a pint of the perfumed Water, and having gradu- ally added the warm Oil solution to the emulsion of Almonds in the mortar, rubbing them constantly, then add the solution of Borax and shake them well together, then add enough of the perfumed Water to make a pint and strain the mixture through coarse cheese cloth to remove larger particles of Almond. 4280. Pimple Lotion. — Carbolic Acid 1 drachm, Borax 4 drachms, Glycerin 2 fl. ounces, Tannin 2 drachms, Alcohol 3 fl. ounces, Rose Water 10 flounces, mix and dissolve. Apply night and morning. 4281. Milk of Almonds. — Bitter Almond, Sweet Almond, each 1 ounce, Alcohol Glycerin, each, 3 ounces, Oil of Bitter Almonds 30 minims. Water TOILET PREPARATIONS AND PERFUMES. 1149 sufficient to make a pint. Blanch the Almonds, beat to a paste, add the Glycerin, dissolve the Oil of Almonds in the Alcohol and add, then add enough Water to make a pint and strain through cheese cloth to remove the coarser particles of Almond. This may also be made by mixing i ]A. ounce Expressed Oil of Almond with 8 ounces of Water, in which ]/z ounce of Borax has been dissolved and adding to the mixture 3 ounces of Glycerin, and 3 ounces of Alcohol in which 10 drops of Essential Oil of Almond is dissolved, and Water enough to make 1 pint. This is used as a bland application for sunburn, tan, etc., also as a vehicle for other medicinal substances. 4282. Milk of Roses. — This may be made in the same manner as Milk of Almond, except that Oil of Rose 1 5 drops, instead of Essential Oil of Bitter Almond, and Rose Water instead of Water, are to be used with the other ingredients. Another formula is Sweet Almonds, blanched, 4 ounces, Rose Water 1 pint, Alcohol 2 ounces, Oil of Rose 20 minims, White Wax, Spermaceti, Castile Soap, each, 2 drachms. The Almonds are blanched and beat with the Rose Water ; the Wax Soap and Spermaceti are melted together by water-bath and the Almond Emulsion is gradually mixed by rubbing in a warm mortar with the melted ingredients. The Alcohol in which the Oil of Rose is dissolved is then added to the mixture. By using Pistachio Nuts instead of Almonds, a finer preparation may be made. 4283. Lait Virginal. — Tincture of Benzoin l / z ounce, Cologne 2 ounces, Glycerin 2 ounces, Rose Water or other Perfumed Water 12 ounces; mix the Tincture of Benzoin with the Cologne, and having mixed the Water and Glycerin arrange a funnel in such a manner that the latter mixture will fall drop by drop into the former, by which process little or no precipitation of the resinous matter is formed, but a fine, smooth, milky preparation is pro- duced. This is much used as a wash for the complexion. Tincture of Myrrh, or Tincture of Tolu, may be used instead of Tincture of Benzoin in this preparation. 4284. Glycerin Lotions. — Quite a variety of preparations are, sold as Glycerin Lotions, the most common being Rose Water and Glycerin, equal parts of each, mixed ; or two parts of Rose Water to one of Glycerin. Lime Juice and Glycerin, usually made with equal parts of Lime Juice, Glycerin Rose Water, is also a favorite application for tan and freckles, and is some- times applied to the hair. Other Waters may be used instead of Rose Water ; Cherry Laurel or Orange Elower Water, making fine preparations. 4285. Hair Gloss.— Glycerin 12 ounces, Cologne 4 ounces. Mix them. Hair Gloss may also be made with Glycerin and Rose Water, or Orange Flower Water, mixed equal parts by measure. LIP SALVES AND COSMETICS. Lip Salves are used for softening the lips, preventing them from cra< king, curing sores, etc., and arc sometimes employed to impart 1150 TOILET PREPARATIONS AND PERFUMES. a color to them. The following formulas will suffice. Lip Salves are usually put up in small metal, glass or porcelain boxes. 4286. Lip Salve.— Oil of Sweet Almond 4 ounces. White Wax, Sper- maceti, each, 1 ounce, Essential Oil of Almonds, Oil of Bay Leaves, each, 15 drops. Melt the Wax and Spermaceti together, add the Almond Oil and while cooling the Perfuming Oils, and stir constantly until cold. 4287 Lip Salve.— The foregoing preparation is liable to deteriorate by age, this one will keep indefinately and is to be preferred. Petrolatum 8 ounces, White Wax or Paraffin 1 ]4. ounce, Tannin 1 drachm, Oil of Lavender, Oil of Bergamot, each, 1 drachm, Oil of Rose Geranium 2 drachms. Melt the Petrolatum and wax together and add the Tannin ; while cooling, add the oils and stir until cold. 4288. Coral Lip Salve. — This may be made by adding to either of the foregoing iormulas, 10 grains of Carmine for each ounce of the lip salve. It is best reduced to a fine powder in a mortar and then rubbed with a small portion of the salve, to a smooth mass, the remainder being gradually mixed with it. NAIL COSMETICS. Powder and ointment for the nails is sometimes called for as toilet preparations, and may readily be made by druggists. 4289. Nail or Manicure Powder.— This is for polishing, smoothing and cleaning the nails. Pumice Stone, in powder, 8 ounces, Powdered French Chalk 2 ounces, Carmine No. 40, in powder, 1 drachm, Bulk Perfume, Rose or Violet y 2 ounce. 4290. Nail or Manicure Salve.— This is for softening the nails, curing hang nails, etc. Petrolatum 1 ounce, Castile Soap, in powder, 1 drachm, Oil of Bergamot 10 drops, or other more expensive perfuming Oils if desired. Mix them thoroughly. This is to be applied at night and the fingers covered with gloves. PERFUMES FOR THE HANDKERCHIEF. Handkerchief Extracts, or "Perfumes" as they are popularly called, are kept by nearly all druggists and constitute quite an im- portant part of their trade. It will be inexpedient in this volume to give anything but a brief outline of the manner of making them, and a very few formulas for the more popular odors. They are made by but few druggists, — not because they are difficult to make, but because it is difficult and expensive to obtain the material requi- site to manufacture them. The following are the extracts, essences, TOILET PREPARATIONS AND PERFUMES. 1151 etc., necessary to be made and kept on hand for the manufacture of perfumes. The processes are adapted to the conveniences always at hand. Perfume Laboratories are supplied with machinery for the purpose. CLASS A. Extracts of Flowers from Pomades. The Pomades used for making these Extracts are prepared by Eufleurage (see page 645), and may be obtained of perfumers and New- York jobbers. They cost from $2.00 to $2.50 per pound, some of them, as Violet, costing much more. 4291. To make Triple Extracts from Pomades.— First. Take equal parts, by weight, of the required Pomade and the strongest Cologne Spirit (Deodorized Alcohol). Divide the Pomade into three equal parts, and put one part (one-third) of the Pomade and all of the Cologne Spirit in a glass or copper jar that will hold double the quantity, and can be stopped air-tight. (An ordinary glass fruit jar is just the thing for small quantities.) Put the jar in a water-bath, and keep at only a moderate heat (just sufficient to keep the Pomade melted) for three or four days, agitating frequentjy, then remove from the water-bath, cool, and pour the liquid extract from the Pomade. This product may be termed the Single Extract. Second. Take another part (one-third) of the fresh Pomade, and macerate it in the same manner as before, with the Extract which has been obtained from the first maceration. This product may be termed the Double Extract. Third. Take the remaining third of the fresh Pomade, and macerate it in the same manner as before, with the product of the previous macerations. When this maceration is completed, surround the jar containing the Pomade and Extract with ice, that all particles of fatty matter may be congealed. When thoroughly cold, pour off the Extract, straining through a little cotton wool into bottles, and keep closely stopped. This constitutes the Triple Extract, and is the finest and strongest Extract that can be obtained. The Pomade that remains after the Extract has been poured off may be again treated in a similar manner with Fresh Cologne Spirit, and the product will be a very fine Extract, but not as strong as the first. It will, perhaps, about correspond to the Single Extract, which may be used for another batch, or for making Colognes or cheap Perfumes. After the Pomade has been thus successively treated, it is called Washed Pomade, and is very good for making Cosmetics and Pomades for the hair. The following list embraces the Extracts made in the manner described, from Pomades readily obtainable in the market. 4292. Triple Extract Cassie or Acacia. — From Cassie Pomade. 4293. Triple Extract Jasmine.— From Jasmine Pomade. 1152 TOILET PREPARATIONS AND PERFUMES. 4294. Triple Extract Orange Flowers.— From Orange Flower Pomade. 4295. Triple Extract Rose. — From Rose Pomade. 4296. Triple Extract Tuberose.— From Tuberose Pomade. 4297. Triple Extract Violet.— From Violet Pomade. Others may be made in the same manner. The Extracts as thus prepared, are used only for combinations. They require something to give them permanence before putting up for sale, and Handkerchief Extracts of the same name contain such additions. CLASS B. Essences from Essential Oils. These are simply solutions of the best quality of Ottos or Essen- tial Oils, in the strongest Cologne Spirit (deodorized Alcohol). They are chiefly used in combining with other perfumes, and they should be kept on hand, prepared in small quantities ready for use. { Oil of Bitter Almonds 1 part, ( Cologne Spirit, 9 parts. \ Oil of Bergamot 1 part, I Cologne Spirit 9 parts. i Oil of Cassia, 1 part, ( Cologne Spirit, 9 parts. ) Oil of Cloves 1 part, /. Cologne Spirit, 15 parts. \ Oil of Lavender, English, . . . 1 part, ( Cologne Spirit 9 parts. \ Oil of Lemon, 1 part, I Cologne Spirit, 9 parts. \ Oil of Lemon-grass, 1 part, I Cologne Spirit, 15 parts. S Oil of Neroli (Bigarade), . . . . 1 part, ( Cologne Spirit, 15 parts. ) Oil of Orange Peel 1 part, t. Cologne Spirit, 9 parts. 4298. Essence Almond. — 4299. Essence Bergamot. 4300. Essence Cassia. — 4301. Essence Cloves. — 4302. Essence Lavender.- 4303. Essence Lemon.— 4304. Essence Lemon-grass or Verbena. 4305. Essence Neroli. - 4306. Essence Orange.— 4307. Essence Patchouly. J Oil of Patchouly 1 part, I Cologne Spirit, 20 parts. _ _ _, \ Oil of Rose (best Kissanlik) . . . . 1 part, 4308. Essence Rose.— , _ , „ . . , H > Cologne Spirit 60 parts. 4309. Essence Rose Geranium. \ Oil Rose Geranium, . . . 1 part, ( Cologne Spirit, ... 20 parts. \ Oil of Rosemary 1 part, 4310. Essence Rosemary.— . J ' Cologne Spirit, 9 parts. TOILET PREPARATIONS AND PERFUMES. 1153 _ _ , . \ Oil Santalwood (true), i part, 431 1. Essence Santal.— . „ , „ . . v ( Cologne Spirit, 20 parts. „ „, , T , ) Oil Ylang Ylang 1 part, 4312. Essence YlaHg Ylang.— '> „ , ° . . , ^ s s \ Cologne Spirit 60 parts. CLASS C. Extracts or Tinctures from Odorous Substances. These are Extracts or Tinctures of Odorous Substances that are used in Perfumes, chiefly to give permanence to the more volatile odors. They should be kept on hand ready to combine as desired. Most of them require long maceration to extract their odorous principle. 4313. Extract Ambergris.— \ ' a ' .' ' , ' ^° ° & / Cologne Spirit 60 parts. Rub the Ambergris fine and macerate for thirty days in warm place, in a tightly stopped bottle. 4314. Extract Angelica.- ( Angelica Root (true) 1 part, ( Cologne Spirit, 4 parts. Reduce the Angelica Root to coarse powder, and macerate for thirty days, with the Cologne Spirit. Press out and filter. 4315. Extract Civet.-] Civet,. I part, ( Cologne Spirit, ........ 60 parts. Macerate for thirty days in a tightly stopped bottle in a warm place. r Fine Grain Musk, 2 parts, 4316. Extract Musk.— 1 Carbonate of Potassium 1 part, ( Cologne Spirit, 120 parts. Macerate for thirty days in a warm place in a tightly stopped bottle. 4317- Extract Musk Root or Sumbul.- j Sumbul Root ' ■ • J P art ' ' Cologne Spirit, . . 4 parts. Reduce the Musk Root to a coarse powder, and macerate for thirty days. Express and filter. 4318. Extract Musk Seed or Ambrette.— \ Musk Seed ' " ' l part ' ( Cologne Spirit, . 4 parts. Macerate for thirty days. Express and filter. r Orris Root 3 parts, 4319. Extract Orris or Violet.— •' Cologne Spirit enough to '. make 4 parts. Reduce the Orris Root to a coarse powder, and macerate for thirty days with four parts of Cologne Spirit, then transfer to a percolator and percolate, adding fresh Spirit through the percolator until four parts are obtained. This is much used as a substitute for Violet. 4320. Extract Tonqua.- } JojiquaBeans 1 part, ' < ologne Spirit 9 parts. Cut the beans fine, crush, and macerate for thirty days. 1154- TOILET PREPARATIONS AND PERFUMES. _ . t ,. ... \ Vanilla i part, 4321. Extract Vanilla.— }_,'.. F f Cologne Spirit, 9 parts. Cut the Vanilla in fine pieces and rub with White Sand to a coarse powder, add the Cologne Spirit and macerate for thirty days in a warm place. JWild Ginger (Canada Snake Root), 1 part, . Cologne Spirit, 4 parts. Reduce the drug to a coarse powder, and macerate for thirty days in the Cologne Spirit. Express and filter. Balsam Peru, Tolu, Benzoin, Styrax, and some other odoriferous bodies are also used in perfumes, but no special extract need be prepared of them, 1 part to 9 of Cologne Spirit being used to make an extract or tincture. The druggist will, of course, make up these preparations in such quantities only as his trade demands, but it is best to have some of each kind on hand. The Citrine Oils, Bergamot, Lemon and Orange, change quickly if not dis- solved in spirit, and it will be found advantageous to dissolve these, while fresh, in Cologne Spirit, and keep them in this way. ODORS OF FLOWERS, Or Handkerchief Extracts. Having now prepared the elements, as they may be termed, of Perfumery (Classes A, B and C), the druggist may prepare any com- bination that may be desired. The formulas which follow are for those which have the most sale on the market, and which time has demonstrated to be good and salable perfumes. There may be of course as many combinations of odors as there are stars in the heavens : but it is not best to encourage a multiplicity of odors, but rather a familiarity with a few good ones, which will soon come to be favorites with the customers of the druggist. Since the introduction of bulk perfumes, many old and favorite odors have gone out of use, and many new ones come in. No standard has yet been established for many of the newly-named perfumes, and they are put up as the fancy of the fabricateur and the harmony of odors may direct. The formulae which follow make only the best grade or quality of perfumes. If the druggist desires to make cheaper goods, any of these may be diluted with Cologne Spirit to meet the desired cost. And in fact this is much better than to try to make them cheaper by using inferior material, because, although they may be weak, they will preserve their purity and delicacy of odor. TOILET PREPARATIONS AXD PERFUMES. 1155 For other combinations our readers are referred to more elaborate works on the subject, and to the published formulas from reliable sources. The essences, extracts, etc., which are directed to be used in the formulas are those which are given in the foregoing classes. 4323. Essence Bouquet — Esprit de Botiquet. — Essence Rose 8 parts, Essence Lemon 1 part, Essence Bergamot, Extract Orris, each, 4 parts, Ex- tract Ambergris, Essence Santal, each, 1 part. Mix. 4324. Extract Frangipanni. — Essence Neroli, Essence Rose, each, 2 parts, Essence Santal, Essence Cassia, Essence Rose Geranium, each, 1 part, Extract Musk, Extract Ambergris, Extract Civet, each, 1 part, Triple Extract Tuberose, Triple Extract Orange Flowers, each, 2 parts, Cologne Spirit 5 parts. Mix. 4325. Extract Jockey Club. — Triple Extract Rose, Triple Extract Tube- rose, each, 4 parts, Triple Extract Cassie, Triple Extract Jasmine, each, 2 parts, Extract Orris 3 parts, Extract Ambergris, Extract Civet, each, 1 part, Essence Rose 2 parts, Cologne Spirit 5 parts. Mix. 4326. Extract Lily of the Valley. — Triple Extract Tuberose 8 parts, Triple Extract Jasmine 1 part, Triple Extract Orange Flower, Triple Ex- tract Cassie 2 parts, Triple Extract Rose 4 parts, Essence Ylang Ylang 1 part, Essence Almonds X part, Extract Vanilla 3 parts, Cologne Spirit 5 parts. Mix. 4327. Extract Musk. — Extract Musk 10 parts, Extract Civet, Extract Ambergris, Extract Musk Seed, each, 4 parts, Essence Rose 3 parts, Extract Wild Ginger 1 part, Cologne Spirit 5 to 20 parts, according to strength de- sired. Mix. 4328. Extract Night Blooming Cereus. — Triple Extract Rose 8 parts, Triple Extract Orange Flower 2 parts, Essence Neroli 2 parts, Extract Vanilla 2 parts, Extract Orris 3 parts, Extract Musk, Extract Civet, each, 1 part, Essence Almond T V part, Tincture Benzoin ^$ part. Mix. 4329. Extract Mary Stewart. — Triple Extract Rose 3 parts, Triple Extract Cassie 1 part, Triple Extract Tuberose 2 parts, Essence Rose 3 parts, Essence Ylang "Slang 2 parts, Essence Rose Geranium 2 parts, Essence Orange X part, Extract Orris 2 parts, Extract Musk 1 part, Extract Ambergris 1 part. Tincture Benzoin, Extract Tonqua, each, % part, Cologne Spirit 5 parts. Mix. 4330. Extract Ilang-Ilang, or Ylang- Ylang. — Essence Ylang-Ylang S parts, Essence Rose 2 parts, Extract Orris 2 parts, Triple Extract Jasmine, Extract Musk, Essence Orange, each 1 part. Mix. 4331. Extract Ocean Spray, or Sea Breeze.— Triple Extract Jasmine, Triple Extract Cassia, each, 4 parts, Triple Extract Rose 6 parts, Essence Bergamot, Essence Lavender, each, 3 parts, Essence Santal 1 part, Extract Ambergris, Extract Civet, each, 1 part, Cologne Spirit 5 parts. Mix. 1156 TOILET PREPARATIONS AND PERFUMES. 4332. Extract Patchouly. — Essence Patchouly 8 parts, Essence Rose, Essence Rose Geranium, each, 2 parts, Cologne Spirit 4 parts. Mix. 4333. Extract Wild Olive.— Triple Extract Rose 8 parts, Triple Extract Jasmine, Triple Extract Violet, each, 4 parts, Triple Extract Cassie 2 parts, Essence Rose 4 parts, Essence Ylang Ylang 2 parts, Extract Musk, Essence Ambergris, each, l / 2 part, Cologne Spirit 5 parts. Mix. 4334. Extract White Rose. — Triple Extract Rose, Triple Extract Violet (or Extract Orris), Essence Rose, each, 4 parts, Triple Extract Jasmine 2 parts, Essence Patchouly 1 part. Mix. This may be diluted with 4 parts of Cologne Spirit if desired. 4335. Extract Stephanotis. — Triple Extract Cassie, Triple Extract Tuberose, each, 4 parts, Triple Extract Jasmine 2 parts, Essence Rose 3 parts, Extract Musk, Extract Tonqua, Essence Neroli, each, 2 parts, Extract Orris 8 parts, Extract Wild Ginger 1 part, Tincture Benzoin 1 part, Cologne Spirit 5 parts. Mix. 4336. Extract Upper Ten. — Triple Extract Rose, Triple Extract Jas- mine, Triple Extract Violet (or Extract Orris), each, 6 parts, Extract Musk 4 parts, Cologne Spirit 6 parts. Mix. 4337« Extract Violet — Finest. — Triple Extract of Violet) from pomade) 16 parts, Triple Extract Cassie 3 parts, Extract Orris 4 parts, Tincture Tolu 1 part, Tincture Vanilla 1 part, Cologne Spirit 6 parts. Mix. 4338. Extract Violet — Good. — A good Extract of Violet, such as is ordinarily sold, may be made with Triple Extract Cassie 2 parts, Triple Ex- tract Rose, Triple Extract Tuberose, each, 1 part, Extract Orris 6 parts, Essence Almonds ^ part, Tincture Tolu 1 part, Cologne Spirit 3 parts. Mix. The formulas given for handkerchief extracts are merely sample formulas representative of combinations that are popular on the market. A great variety of other odors by various names are found, and may be made by druggists by combining various extracts, essences, etc. COLOGNES AND TOILET WATERS. Colognes are fragrant compounds of much less strength and per- manence of odor than the foregoing Extracts. In addition to their legitimate use as toilet waters, they now take the place, to a large extent, of the cheaper grades of perfume that were formerly sold. As with the Handkerchief Extracts, the combinations that may be made are almost infinite, though but few have ever met with great public favor. The formulas which follow represent those most widely known and esteemed as Colognes; but, as any of the Handkerchief Extracts TOILET PREPARATIONS AND PERFUMES. 1157 may be made into Colognes, by following the " General Cologne Formula," the druggist may choose such as suits his fancy, and have as large a variety as he pleases. Colognes prepared from the Handkerchief Extracts may also be put up as cheap perfumes ; the grades that the druggist wishes to prepare may be regulated by the amount of Cologne Spirit added. For second grade perfumes, taking Handkerchief Extract i part, Cologne Spirit i part. For third grade perfumes, taking Handkerchief Extract i part, Cologne Spirit 2 parts, and for Colognes, the following General Cologne Formula : Handkerchief Extract i part, Cologne Spirit 3 parts, Water (distilled) * q. s. Mix the Extract with two and a half parts of the Cologne Spirit, and add Water gradually until, when shaken up, it remains, after standing a short time, just a trifle cloudy or milky, then add the balance of the Cologne Spirit, and set away for a month or more before using. These Colognes may be named from the Extracts of which they are made, as White Rose Cologne, Marie Stewart Cologne, Upper Ten Cologne, etc., and the druggist may have no lack of cheaper grades of perfumes and Colognes by following these directions. 4339- Farina Cologne. — Essence Bergamot 10 parts, Essence Neroli 1 part, Essence Lavender 2 parts, Essence Lemon 2 parts, Essence Orange 2 parts, Essence Cloves 1 part, Essence Cassia 1 part, Essence Rose 2 parts, Essence Rose Geranium 1 part, Triple Extract Jasmine 6 parts, Extract Angelica 1 part, Extract Orris 3 parts, Extract Musk Seed 2 parts, Essence Nutmeg 1 part, Essence Spearmint 2 parts, Essence Cedrat, 2 parts, Essence Thyme %. part, Essence Cajeput X P art > Cologne Spirit 400 parts, Distilled Water 60 parts. Mix the Essences, etc., with the Cologne Spirit, and gradu- ally add the Water. If it should remain milky after the addition of the Water, add enough Cologne Spirit to clear. 4340. Floral Cologne. — Essence Bergamot 10 parts, Essence Cassia 4 parts, Essence Orange 6 parts, Essence Lavender 2 parts, Essence Lemon 6 parts, Essence Santal 2 parts, Essence Neroli 2 parts, Essence Rose Geran- ium 4 parts, Extract Orris 4 parts, Extract Tonqua 2 parts, Extract Amber- gris 2 parts, Cologne Spirit 300 parts, Rose Water 50 parts. Mix the Essences, etc., with the Cologne Spirit, and gradually add the Rose Water. If milky after standing, add enough Cologne Spirit to make clear. 4341. German Cologne, A. I. — Essence Rose Geranium 8 parts, Essence Orange 10 parts, Essence Cassia 6 parts, Essence Bergamot 10 parts, Essence Cloves 1 part, Essence Neroli 2 parts, Essence Lavender 4 parts, Essence * If Rose Water or Oranpe Flower Water is added Instead of Distilled Water, the .mm be finer. Rose Water may be used with all Extracts, but Orangi Water is preferable in thoa pounds which contain Triple Extract < >range Flowers or Neroli, 11;")8 TOILET PREPARATIONS AND PERFUMES. Rose 4 parts. Essence Verbena 2 parts, Essence Santal 4 parts, Extract Am- bergris 1 part, Extract Musk 1 part, Tincture Cardamom 1 part, Cologne Spirit 300 parts, Rose Water 50 parts. Mix the Essences, etc., with the Cologne Spirit, add the Rose Water gradually, and then if milky, enough more Cologne Spirit to make clear. 4342. German Cologne, 2d. — Essence Bergamot 10 parts, Essence Lemon 6 parts, Essence Orange 6 parts, Essence Rosemary 6 parts, Essence Cassia 4 parts, Extract Orris 4 parts, Extract Tonqua 2 parts, Extract Musk Seed 4 parts. Extract Angelica 1 part, Extract Wild Ginger 2 parts, Tincture Benzoin 1 part, Cologne Spirit 400 parts, Rose Water 60 parts. Mix the Essences, etc., with the Cologne Spirit, add the Rose Water gradually, and if milky, enough more Cologne Spirit to make clear. 4343. Lavender Cologne, or Water. — Essence Lavender 3 parts, Es- sence Lemon 2 parts, Essence Cassia 1 part, Essence Cloves 1 part, Essence Santal 1 part, Cologne Spirit 60 parts, Water 10 parts. Mix the Essences with the Cologne Spirit, add the Water gradually, and then enough Cologne Spirit to clear, if milky. 4344. Musk Cologne. — Essence Bergamot 2 parts, Essence Lavender 2 parts, Essence Lemon 4 parts, Essence Neroli, 1 part, Extract Musk 4 parts, Cologne Spirit 60 parts, Rose Water 10 parts. Mix the Essences, etc., with the Cologne Spirit, add the Rose Water gradually, and then enough Cologne Spirit to make clear, if milky. 4345' White Rose Cologne. — Oil Neroli Bigarade 1 drachm, Oil Neroli, Petit grain, l / z drachm, Oil Bergamot 2 drachms, Oil Patchouly 1 drachm, Oil Rose 3 drachms, Extract Musk 2 ounces, Tincture Tolu 2 ounces, Cologne Spirit 7 pints, Rose Water 1 pint. Dissolve the Oils in the Spirit, and add the Rose Water, let stand 30 days, and filter. 4346. Hoyt's German Cologne. — The following formula has been pub- lished as similar to Hoyt's German Cologne : Oil Bergamot 1 ounce, Oil Lemon 1 ounce, Oil Neroli X ounce, Oil Santal Wood y 2 ounce, Camphor 20 grains, Cologne Spirit 7 pints, Rose Water 1 pint. Mix and let stand a month, then filter. 4347. Florida Water. — Oil of Lavender Flowers, English, 6 fl.drachms, Oil of Bergamot 2 fl.drachms, Oil of Lemon 1 >£ fl.drachm, Oil of Cloves 20 minims, Oil of Cassia 10 minims, Oil of Orange 30 minims, Essence Rose 60 minims, Essence Neroli 10 minims, Cologne Spirit 15 fi. ounces. Mix them. 4348. Violet Water. — This may be made by diluting Extract of Violet with 4 parts of Cologne Spirit. Other Toilet Waters may be made in the same general manner. 4349. Other Colognes and Toilet Waters may be made by the general formula. They may be made as the fancy of the maker may select, and may be made stronger or weaker as may be desired, to correspond with the trade for which thev are made. TOILET PREPARATIONS AND PERFUMES. 1159 SACHET POWDERS. A great variety of Sachet Powders may be made by adding to an Aromatic Base, composed of Ground Roots, Barks, Woods, Flowers, Leaves, etc., Bulk Perfumes or Essential Oils. A few formulas for the best selling powders are given here, and others may be made in the same general way. 4350. General Base for Sachet Powder.— Orris Root, in coarse pow- der, 1 pound, Santal Wood, ground, 4 ounces, Vanilla Beans, ground or cut fine, 1 ounce, Rose Leaves, (flowers,) ground, 6 ounces, Extract Musk, % ounce, Extract Civet, )A ounce. Mix them well together. To make any variety of Sachet Powder, add to 8 ounces of this 1 ounce of the Bulk Per- fume, of the kind desired and mix them thoroughly. The following are formulas for those most popular : 4351. Frangipani Sachet. — Powdered Orris 3 pounds, Ground Vitivert %. lb., Ground Santal % pound, Ground Vanilla Beans % pound, Ground Ton- quin Beans 2 ounces, Oil Neroli 60 minims, Oil Santal 40 minims, Oil Berga- mot 60 minims, Oil French Geranium 60 minims, Otto Rose 30 minims. Extract Musk 1 ounce, Extract Civet % ounce. Mix well. 4352. Heliotrope Sachet.— Powdered Orris 2% pounds, Ground Rose Leaves 1 pound, Ground Vanilla Beans 6 ounces, Ground Tonquin Beans 4 ounces, Extract Musk lyi ounces, Extract Civet yi, ounce, Essential Oil of Almonds 7 minims. Mix. 4353. Rose Sachet.— Powdered Orris j£ pound, Ground Rose Leaves 1 >£ lbs., Ground Santal Wood 4 ounces, Ground Patchouly 2 ounces, Extract Civet yi ounce, Oil French Geranium 30 minims, Otto Rose 20 minims. Mix. 4354. Jockey Club Sachet.— Powdered Orris 3 pounds, Ground Santal Wood Yz pound, Oil Bergamot 1 ounce, Otto Rose 30 minims, Extract Musk 2 ounces, Extract Civet 1 ounce. 4355. Essence Bouquet Sachet.— Powdered Orris 4 pounds, Ground Cassie Leaves (Flowers) 1 pound, Ground Rose Leaves (Flowers) 1 pound, Ground Vanilla Beans 3 ounces, Essence Bergamot 1 ounce, Essence Lemon 1 ounce, Oil French Geranium 60 minims, Extract Musk 2 ounces, Extract Ambergris >£ ounce. 4356. Ylang-Ylang Sachet.— Ground Rose Leaves 1 pound, Ground Cassie Leaves 1 pound, Ground Pimento % pound, Ground Tonquin Beans 2 ounces, Ground Vanilla Beans 2 ounces, Powdered Orris 3 pounds, Oil Pimento 60 minims, Oil Bergamot 120 minims, Oil French Geranium 60 minims, Oil Ylang-Ylang 120 minims, Otto Rose 20 minims, Extract Musk 1 ounce, Extract Civet ]/% ounce, < aim Benzoin (Ground) 1 ounce. Mix. 4357. Violet Sachet.— Powdered Orris 3 pounds, Essence Bergamot 30 minims, Essential Oil of Almonds 20 minims, Otto Rose 20 minims, Extract Musk 1 ounce. Mix. 1160 TOILET PREPARATIONS AND PERFUMES. 4358. Pot Pouri for Rose Jars. — Mixtures of Rose Leaves, etc., for filling Rose Jars are now considerably used. A favorite mixture for this pur- pose is as follows : Rose Leaves (Flowers) whole, 1 pound, Patchouly Leaves 4 ounces, Violet Flowers 4 ounces, Vanilla, cut fine, y* ounce, Cinnamon, in coarse powder, x / 2 ounce, Orris Root, in coarse powder, 4 ounces, Allspice, in coarse powder, yi ounce, Cloves, in coarse powder, % ounce, Oil Bergamot yi. ounce, Musk Extract 1 ounce. Mix the Oil and Musk Extract thoroughly with the powdered drugs, and then with the Leaves, etc. By grinding the Leaves, etc., to a coarse powder, this may be used as a Sachet Powder ; other combinations may be made in the same manner, by using other flowers, etc., in combination, as Lavender, Vitivert, etc. SMELLING SALTS OR PUNGENTS. The sale of Smelling Salts, or " Pungents," which, for a time was quite limited, has again revived. The following formulas make satisfactory preparations: 4359. Pungent Smelling Salts. — If something fine is desired without regard to cost this is recommended : Carbonate of Ammonium, crushed into a coarse powder, 6 ounces, Sal Ammoniac, granulated, 1 ounce, Pure Potash (Caustic Potash), crushed fine, 2 ounces, Orris Root, in coarse powder, 4 ounces, Lemon Peel, in coarse powder, Rosmary Leaves, in coarse powder, Lavender Flowers, in coarse powder, each, 1 ounce, Cloves, Cinnamon, Cala- mus, each, in powder, yi ounce, Oil of Bergamot l /z ounce, Oil of Lemon 2 drachms, Extract of Musk or Civet ^ ounce, Stronger Water of Ammonia Yz ounce. Mix them well together. 4360. Smelling Salts. — A more common article may be made as follows : Carbonate of Ammonium, crushed to a coarse powder, 1 2 ounces, Powdered Orris 4 ounces, Powdered Cloves, Powdered Cassia, Powdered Calamus, each, 1 ounce, Stronger Water of Ammonia 1 ounce, Oil of Bergamot yi ounce, Oil of Lavender X ounce. Mix them. 4361. Preston's Salts. — Carbonate of Ammonium, crushed, 4 ounces, stronger Water of Ammonia %. ounce, Oil of Cloves, Oil of Lavender, Oil of Bergamot, each 10 drops. Mix them well together. 4362. Smelling Salts. — Extemporaneous. — By crushing Carbonate of Ammonium, and adding to each ounce 30 drops of Stronger Water of Ammonia, and 30 drops of Bulk Perfume. 4363. Vinegarettes. — These are employed like smelling bottles and for similar purposes. Any inert Aromatic substance, as Orris or a mixture of Aromatic powdered drugs, may be saturated with Glacial Acetic Acid with which one-fourth the quantity of Bulk Perfume is mixed. The Toilet Vine- gars mentioned further on, may also be employed for the same purpose. TOILET PREPARATIONS AND PERFUMES. 1161 TOILET SOAPS. Toilet Soaps are seldom made except by experienced soap makers. The bases of Toilet Soaps are the common hard soaps referred to under the article on soaps, page 738. For making the finer grades of Toilet Soaps these are shaved, " milled " or ground, and mixed as may best be suited for the required product, and the perfuming Oils and ingredients worked into them. The mass is then slightly moistened if necessary and made up into the required quantity for cakes, and pressed in a dye into the shape desired by means of a strong press. The cheaper Toilet Soaps are made in the same manner as is directed for making Hard Soaps in the article referred to, but are more or less perfumed with essential Oils or odorous substances. An infinite variety of Toilet Soaps are supplied by soap makers, and druggists may themselves make them by securing the proper appliances. The perfumes for the soaps depend upon the price at which they are to sell, and may be selected from the formulas already given for bouquets of different kinds, and from the essential Oils suitable for the purpose. Glycerin in small quantities is fre- quently added to Toilet Soaps, and they are variously colored with harmless ingredients to suit the taste or caprice of the manufacturer. As so great a variety of Toilet Soaps are required, and so few make them, it would be inexpedient to give formulas for them here. TOILET VINEGARS. A class of preparations for the toilet called Aromatic Vinegars have a limited sale. They are chjpfiy used after bathing and wash- ing the hands and face to impart a freshness to the skin, and for their agreeable odor. The following formulas will suffice 4364. Aromatic Vinegar.— Glacial Acetic Acid 8 ounces, Cologne Spirit 4 ounces, Camphor, in small pieces, 1 ounce, Oil of Cloves 45 minims, Oil of Rosmary 30 minims, Oil of Bergamot, Oil of Cinnamon, Oil of Lavender, Oil of Pimento, Oil of Neroli, each, 15 minims. Mix, let stand until the ingredi- ents are dissolved, and filter. 4365. Aromatic Vinegar.— This may also be made by mixing any kind of Hulk Perfume with the other ingredients instead of the essential Oils, as : Glacial Acetic Acid 8 ounces, Cologne Spirit 2 ounces, Camphor 1 ounce, Bulk Perfume or Cologne (as desired), 2 ounces. Mix, dissolve and filter. To use these Vinegars a small quantity is added to a bowl of Water, and usually applied with a soft sponge. 1162 TOILET PREPARATIONS AND PERFUMES. TOILET WATERS. Toilet Waters as they are known in the market are not as their name would indicate, Waters, but solution of essential Oils or odor- ous principles in Alcohol or a partly Alcoholic liquid, prepared either by solution or distillation. These are known as Eau de Cologne, Eau de Lavande, Eau de Violette, etc., and have been noticed under Perfumes and other headings. The name is also ap- plied in a general way to perfumed Waters and spirits made by dis- tilling herbs and odorous substances, with Water or a diluted Alco- holic liquid; but as these have been already noticed under other headings, as Aquae, Spiritus, etc., further formulae will be unneces- sary. The foregoing formulas comprise most of the Toilet Preparations and Perfumes that are popular or on the market, and all that it is expedient or desirable for druggists to prepare. If it is intended to engage extensively in the manufacture of perfumes and like articles, many other formulas would be required, for which the reader is re- ferred to comprehensive works on perfumery, soap making, etc. PART VI. MISCELLANEOUS FORMULA The formulae which follow for miscellaneous preparations, often required in the druggist's business, are, as far as possible, arranged in classes according to their uses. Only a limited number of such formulas can be given in the space which is devoted to this subject, and we have endeavored to select such as are best suited for the purpose. ADHESIVE PREPARATIONS. Cements. These are generally to be applied to the edges of the articles to be mended, previously warmed, and they are then to be held or bound together with twine or otherwise until the cement hardens. The cements have to be warmed also. 4366. Diamond Cement.— Gelatin 1 ounce, Water 5 ounces, Gum Mastic i l / 2 drachms, Gum Ammoniac }i drachm, Alcohol 2j4 ounces. Dissolve the Gelatin in the Water and continue the heat until the solution has evaporated to about 3 fl. ounces; have the gums previously dissolved in the Alcohol, and to this solution, heated to nearly boiling, add the hot solution of Gelatin, and mix them thoroughly. Put up in small bottles tightly stopped. This cement may be used for china or glass ware, and for attaching wood, ivory, jewels, metallic substances, etc. 4367. Glutina Cement — For glass, china, wood, leather, etc. — Gelatin, Cooper's or Cox's, 3 ounces, Acetic Acid 2 ounces, Carbolic Acid 5 grains, Oil of Cloves 5 minims, Water, enough to make 1 pint. Soak the Gelatin in half a pint of Water for 4 hours, then heat by water-bath in a glass or porce- lain vessel, add the Acids, dissolve, add the Oil of Cloves and sufficient hot Water to make a pint, and strain. 4368. Insoluble or Chrome Cement —For glass and china. — This cement, which is impervious to hot Water, should be freshly made when wanted for use. Gelatin, in small pieces, 1 drachm, Hot Water %. ounce, 1163 1164 MISCELLANEOUS FORMULA. Bichromate of Potassium 1 5 grains. Dissolve the Gelatin in the Water con- tained in a small bottle by means of a water-bath, and while hot add the Bichromate of Potassium and apply as soon as possible, binding the pieces firmly together and setting in the sunlight. The Gelatin and Chrome Salt form an insoluble compound. 4369. Transparent Cement — For china, glass, etc. — Mix in a well- stopped bottle 20 parts of Chloroform and 25 parts of native India Rubber, or Caoutchouc, cut in small pieces ; when dissolved add 5 parts of Mastic and let the whole macerate for 8 or 10 days, shaking daily, then strain quickly through very thin cotton cloth. This makes a very firm Transparent Cement for china and glass, and may be used for other purposes. 4370. India Rubber Cement or Glue — For rubber, etc. — Dissolve Gutta Percha chips or sheet in Bisulphide of Carbon until the solution has the consistence of thick syrup, and strain the mixture with pressure quickly, through a thin cotton cloth. To use this on rubber shave down the edges to be cemented thin, apply the cement freely and warm the parts for a moment, join together and press, clamp or hammer down to hold them firmly until dry. 4371. Aquarium Cement.— Water Lime or Portland Cement, Marble Dust or White Sand, Litharge, each, 4 ounces, Powdered Resin l / z ounce. Mix the powders and make into a putty with boiled Linseed Oil just before using. 4372. Cement for Lamps. — Plaster of Paris wet up with glue Water is generally used, but a more permanent Cement may be made by dissolving 1 ounce of concentrated Lye in 5 ounces of Water, adding 3 ounces of pow- dered Resin, and boiling them together 5 to 10 minutes. Then to make the Cement, just before using mix Plaster of Paris up with this solution to the proper consistence and apply. 4373- Amber Cement. — To cement or join amber, paint the edges to be united with boiled Linseed Oil, press firmly together and v/arm for some time at a degree of heat not high enough to melt the amber. 4374. To join Glass to Metal. — To cement glass, porcelain, earthenware or other hard substances to metal, melt a little shellac and join the substances with it while it is melted. 4375. Metal Cement.— An excellent cement for metallic substances may be made by dissolving shellac to saturation in Water glass, by the aid of heat. 4376. Rubber Tire Cement. — A cement for Rubber Tire bicycles and other similar uses may be made by dissolving India Rubber 1 part in suffici- ent Naphtha, by the aid of gentle heat of water-bath, and when melted add- ing 2 parts of Shellac, and melting them together, by water-bath, the naphtha is evaporated. Pour the melted mass on metal plates or run in sticks. When used the parts are to be well warmed and the cement heated and applied like sealing wax. MISCELLANEOUS FORMULAS. 1165 Glues. Glues are prepared from glue, gelatin, etc., and are used for join- ing substances like wood, ivory, leather, etc., together, and for many other purposes. Some are prepared in solid form, requiring to be melted before using, and others are made to remain liquid by the addition of various substances. See also Gelatin, page 513, and Liquid Glue, page 514, and Tungstic Glue, page 967. 4377- Glue, Ordinary. — This is prepared by melting Glue in Water by the means of a glue pot or water-bath. It is made of different consistence for various purposes, more or less Water being used as required. It must be applied hot and the surfaces to be joined well bound together until dry. 4378. Liquid Glue. — Glue may be first made liquid by melting in Water as above, and then adding Alcohol 1 ounce to about 3 ounces of Glue, used while still liquid, but most Liquid Glue is prepared with Acid, either Acetic or Nitric as directed, page 514. It may be made of any desired consistence, by using more or less Glue. A little Oil of Sassafras or Cloves is generally used to prevent moulding. A good Liquid Glue for bottling may be made with good Glue 1 pound, dissolved by means of a water-bath in Water 1 pint in a porcelain vessel, and when dissolved gradually adding 5 ounces Nitric Acid, with constant stirring, or good Glue s l / 2 ounces, Acetic Acid 5J4 ounces, Oil Sassafras 15 drops, Water, enough to make a pint, made in the same manner. 4379. Water-Proof Glue — Marine Glue. — This is prepared by dissolv- ing separately in a sufficient quantity of pure Ether, 3 parts of Shellac and 1 part of India Rubber, and, when dissolved, mixing the solutions and keeping in tightly stopped bottles. This is insoluble either in hot or cold Water, Acids, etc. Another kind of Glue which will resist moisture, etc., may be made by add- ing a solution of Sandarach, Mastic and Turpentine Gum, each equal parts in Alcohol 16 parts, to Ordinary Glue or Gelatin melted in Water. The quantity to be used depends upon the purpose for which it is required, about 1 ounce to 2 ounces of Glue in a pint being the proportion for ordinary uses. 4380. Elastic or Mouth Glue.— This is prepared by dissolving good Glue in an equal quantity of Water, and adding to it one half as much Glycerin, and one fourth as much sugar as was used of the Glue. This is run into small pieces and may be moistened and applied to paper or other light sub- stances. 4381. Pad Glue.— This is now extensively used for the backs of pads of paper to fasten the leaves together, and for other similar purposes. Glue %, pound, Water '.- pint, Acetic Acid 1 ounce, Glycerin 2 ounces, Aniline red, green, blue, or other fdlur as desired, 1 drachm, or sufficient to color. Make the Glue in the usual manner by melting in the Water in a glue pot or water- 1106 MISCELLANEOUS FORMULA. bath, and add the Glycerin and coloring matter. This may be made more or less brittle or elastic by varying the quantity of Glycerin. Mucilages. Adhesive Mucilages for sticking labels to bottles, tinware, etc., papers together, and for gumming the backs of paper used for stamps, labels, etc., are much used. The following are the various kinds employed for different purposes. 4382. Casein Mucilage.— Heat sour milk with a little Tartaric Acid, which causes the Casein to separate. Collect and press the mass and while still warm add enough of a solution of Borax 1 ounce in 1 pint of Water to nearly dissolve the Casein. This may be used for the back of label paper and other adhesive purposes. 4383. Label Mucilage. — Soak 6 ounces of Glue in 20 ounces of warm Water, and then dissolve by heat ; while warm dissolve in it 3 ounces of granulated Gum Arabic and 8 ounces of Rock Candy. This is for gumming the backs of sheets, for labels, etc., and must be applied, while warm, with a brush. 4384. Stamp Mucilage. — The following is said to be the same as is used for gumming U. S. stamps : Dextrine 2 ounces, Gum Arabic 1 ounce, Acetic Acid X ounce, Sugar 1 ounce, Oil of Sassafras 10 drops, Water 6 ounces. Mix and dissolve by heat of water-bath, and apply with a brush while warm. 4385. Good Cheap Mucilage. — This may be made by soaking 1 part White Glue or Gelatin and 2 parts of Gum Arabic in 10 parts of Water, add- ing ]i part of Sugar, dissolving by gentle heat, straining and adding a few drops of Oil of Cloves to keep. 4386. Dextrine Mucilage. — Dextrine 3 parts, Water 5 parts, dissolve by heat of water-bath. 4387. Mucilage for Tin and Metal. — Most mucilages will not stick on tin or bright surfaced metals, and a mucilage must be specially prepared for this purpose. The following is A 1 : Starch 1 pound, Water 1 1 / 2 pint, Muriate of Tin Solution 4 fl.ounces, Glycerin 1 ounce, Oil of Sassafras 30 drops. Mix the Muriate of Tin solution with the Water and Glycerin, and add to the Starch, boil them together until a clear mucilage is formed, and while cooling add the Oil of Sassafras. Mucilage of Acacia and Mucilage of Tragacanth, which are much used for adhesive purposes, are noticed on pages 630 and 632. Pastes. Pastes for adhesive purposes are made from flour or starch, and are much cheaper than most mucilages for pasting labels, wrappers, MISCELLANEOUS FORMULAE. 1167 etc. When druggists are once accustomed to their use they prefer them to mucilage for that purpose, as they dry quicker, keep in place better, and do not wet the paper like mucilage. The following formulas will be sufficient: 4388. Good Flour Paste.— Wheat Flour 4 ounces, Alum, in powder, 90 grains, Oil of Cloves 5 minims, Carbolic Acid 10 grains, Water 1 pint. Mix the flour with enough Water to make a thin mixture, heat the remainder of the Water to boiling, add the Alum to it and then add it quickly to the mix- ture of flour and Water, stirring them well together, and heating if necessary to make a good smooth paste ; while cooling add the Oil of Cloves and Acid. 4389. Good Starch Paste.— This maybe made in the same manner as the foregoing, only using starch in place of flour ; 1 ounce of Glycerin added is advantageous. 4390. Paste for Tin.— To either of the foregoing formulas, add 1 ounce of Glycerin, X ounce of Acetate of Lead, in powder, and % ounce solution, Muriate of Tin, to the boiling Water, which is added to the flour or starch. BAKING POWDER. In making Baking Powders it is necessary in the first place to choose good and appropriate material, and in the second place to have the articles which enter into the composition dry and very finely powdered. They must then be combined in such proportions that the Acid will exactly unite with the Alkaline base, setting free the Carbonic Acid gas which is united with it, which causes, by its escape through the dough, the lightness of the pastry. In choosing material to combine in Baking Powders it is neces- sary to select such substances as will not react upon each other when mixed dry, but which will combine to liberate the Carbonic Acid gas under the influence of moisture and heat. Cream of Tartar. because of its insolubility is the most serviceable of tin- Acids for this purpose, and Bicarbonate of Sodium, which contains a large quantity of Carbonic Acid gas, readily liberated, when acted upon by an acid, is the best of the Alkaline base. Owing to the uncertain composition and strength of the material used for making Baking Powders, it is difficult to give definite formulas that will work every time to the entire satisfaction of the operator, for the test of the powder in baking is the only 'general way by which it may be known if the articles used are balanced SO as to be neither alkaline nor acid. 11(58 .MISCELLANEOUS FORMULA. It is also very important that the material used be very finely powdered, thoroughly dry, and perfectly mixed. Baking Powders cannot be thoroughly mixed by hand or in a mortar, because small particles of the bicarbonate of sodium will adhere together, and when used will make small yellow spots or points in the pastry ; some kind of a mixer is therefore required that will thoroughly crush these particles and mix all together intimately. Several kinds of mills and mixers are furnished for this purpose. The following formulas will, if properly combined from good material, make ex- cellent Baking Powders, but it should be understood, as previously explained, that the operator should test the powder by baking be- fore sending it out, and if it needs more acid or more alkali, add it until it is properly proportioned to make the best. 4391. Baking Powder, No. 1.— Pure Cream- Tartar, 3 pounds, Pure Bicarbonate Soda, 22^ ounces, Best Roller Flour, 1 pound, Corn Starch }i pound. If preferred, y z pound Corn Starch and y 2 pound Flour may be used in place of 1 pound Flour, in which case the Starch must be finely powdered. Use 1%. teaspoonfuls to 1 quart Flour. This is the best formula. 4392. Baking Powder, No. 2.— Pure Cream Tartar 1 % pounds, Pure Bicarbonate Soda 13 ounces, Tartaric Acid 1 ounce, Best Roller Flour 1 pound, Corn Starch y, pound. Use 2 teaspoonfuls to 1 quart Flour. 4393. Baking Flour, No. 3. — Pure Cream Tartar 2 pounds, Pure Bicar- bonate Soda 1 pound, Roller Flour 1 y. pounds, Tartaric Acid 1 ounce, Corn Starch 1 y. pounds. Use 2 teaspoonfuls to 1 quart Flour. 4394. Baking Powder, No. 4. — Pure Cream Tartar 1 pound, Pure Bicar- bonate Soda 1 pound, Tartaric Acid 3 ounces, Roller Flour 2 pounds, Corn Starch x / z pound. Use 2 teaspoonfuls to 1 quart Flour. This is a good, cheap powder. Keep well covered. CLOTH CLEANING COMPOUNDS, ETC. For cleaning cloth, gloves, lace and delicate fabrics that cannot well be washed in the ordinary way many preparations are put up and sold. Most of them are simply, Gasoline or Deodorized Ben- zine, perfumed with some fragrant oil, but other compounds are also used. Washing compounds are also included under this head- ing. The following are representative of the various preparations: 4395. Fragrant Benzine or Gasoline. — Gasoline 1 gallon, Oil of Berga- mot % ounce. Mix them. Any other volatile oil, as Cloves, Cassia, Laven- der, Lemon, etc., may be used instead of Bergamot. This may be put up by MISCELLANEOUS FORMULAE. 1169 any fancy name, and recommended to clean cloth, silks, gloves, etc., and remove grease spots. 4396. Cloth and Glove Cleaner.— Gasoline, or Deoderized Benzine 1 quart, Alcohol, Chloroform, Ether, each, ^ fl. ounce. Mix them. This may be put up and sold at a fancy price for cleaning silks, gloves, etc. It may be perfumed with lavender or cologne if desired. 4397- Clothes Cleaning Compound — For removing pai7it, grease, dirt, etc. — Water of Ammonia 1 pint, Alcohol 9 fl. ounces, Soap Liniment 6 fl. ounces, Borax, in powder, 4 ounces av., Castile Soap, cut or shaved, 4 ounces av., Boiling Water 6 quarts. Dissolve the Soap and Borax in the boiling Water, and when cool add the other ingredients. This is to be ap- plied by rubbing into the grease spot, and then washed out with clear warm water. 4398. Cleaning Cream. — Ivory, or other White Soap S ounces, Sal Tar- tar yi. ounce, Borax 2 ounces, Oil of Sassafras 1 drachm, Water 1)4 pint. Cut the soap in small pieces and dissolve in the Water by heat of water-bath, add the Borax and Sal Tartar, and while cooling add the Oil of Sassafras, mixing them well together. This removes grease, paint and dirt by rubbing in and washing out with warm water. 4399. Benzin Jelly.— White Soap 12 ounces, Hot Water 18 ounces, Am- monia Water 3 ounces. Dissolve the Soap in the Hot Water, pour in a bottle, and add the Water of Ammonia. Then add to the mixture 2 pints of Gasoline or deodorized Benzin, and shake thoroughly until the mixture is cold and solidified. This is applied by rubbing on the grease spots, and after- wards washing out with warm water. 4400. Erasive Soap.— White Soap 8 ounces, Borax 1 ounce, Sal Tartar 1 drachm, Oil of Sassafras 1 drachm, Water 8 ounces. Cut the soap in shav- ings and dissolve in the Water by heat of a water-bath, add the Borax and Sal Tartar and boil until reduced to 1 pound, then while cooling add the Oil of Sassafras, and make into cakes of about 2 ounces. 4401. Washing Fluid. — Concentrated Lye, or Caustic Soda, 1 pound, Oil of Turpentine 2 ounces, Borax 2 ounces, Camphor l / 2 ounce, Soap Bark, ground, }£ pound, Water of Ammonia % pint, Water sufficient. Steep the Soap Bark for two hours in ]/z gallon of Water, strain and press. Dissolve the Concentrated Lye and Borax in J^ gallon of Water, and add to the de- coction of Soap Lark. Dissolve the Camphor in the Oil of Turpentine and add to the solution, then add the Water of Ammonia, and after standing pour off or strain, add a tablespoonful of this to each gallon of Water used for -Making the cloths before washing, and a little in the washing Water. 4402. Washing Fluid.— Sal Soda 4 pounds, Borax 2 ounces, Sal Tartar I ounce, Water of Ammonia l / z pint, Spirit of Camphor 2 ounces, Oil of Tur- pentine 1 ounce, Hot Water 6 pints. Dissolve the Salts in the hot Water and add the liquids. This may be used the same as the foregoing. 1170 MISCELLANEOUS FORMULAE. 4403. Washing Crystal or Powder is prepared by mixing coarsely pow- dered Borax 8 ounces, with Carbonate of Potash (Sal Tartar) 4 ounces, or Crude Potash 3 ounces. The "1776 "and other similar compounds are made by adding excess of Alkali to Soap while making and evaporating to a mass or granular powder. It requires special machinery, and cannot be made except in large factories. EXTERMINATORS, DESTROYERS AND POISONS. For exterminating or poisoning rats, mice, bugs, flies and vermin generally, a great many different kinds of preparations are put up and sold. The following represent some of the best for the purpose : 4404. Bed Bug Poison or Exterminator.— Corrosive Sublimate, in pow- der, 2 ounces av., Alcohol 1 pint. Dissolve the powder in the Alcohol and apply to the bedsteads where the vermin hide. Another poison for the same purpose may be made with Cyanide of Potas- sium 2 ounces av., Water 1 pint. Dissolve and apply. These may be used for any kind of bugs, ants or vermin to which it can be applied. 4405. Bug and Ant Poison.— As a poison for cockroaches, other bugs and ants, to eat, the following will give satisfaction. Tartar emetic 1 ounce, powdered Sugar 7 ounces. Mix them intimately together and place the powder where the vermin will find it. 4406. Fly Paper. — Formulas for fly papers, both poison and sticky, will be found on pages 230 and 231. The following additional formula for Sticky Fly Paper is given : Common Resin 1 pound, Castor Oil about 5 ounces. Melt the Resin and add sufficient Castor Oil to make it properly adhesive when applied to the paper. As the resins vary, a little less or more than 5 ounces may be needed. Prepare manilla paper or other firm paper by brush- ing over each sheet with a size made of glue ^ pound, melted in hot Water, 1 gallon. This is applied hot, with a brush, to the paper, and the sheets dried by hanging on lines. The Resin compound is then applied warm, with a brush, to the sized sheets, which are then folded together. 4407. Anti-moth Paper. — Carbolic Acid Camphor, Oil of Cedar, each, 1 part, Benzin 8 parts. Dissolve and dip sheets of heavy porous paper in the liquid and hang on lines until the Benzin evaporates. The paper should then be cut up and kept in tin boxes. These sheets are put away in drawers or with firs, etc., to prevent moths. 4408. Rat Poison. — A great variety of poisons for Rats and vermin are put up under various names, and in various forms. They consist mainly of Arsenic, with the addition of some coloring matter or other substances. MISCELLANEOUS FORMULAE. 1171 Rough on Rats is an example of proprietary Rat Poisons. It consists of Arsenic colored a little with ivory black or some other black substance. It is mixed with lard and sugar and spread upon bread. 4409. Rat Paste Poison. — This maybe made by mixing Arsenic with brown sugar, equal parts, and making into an ointment or paste with lard, the same quantity as is taken of the Arsenic. Tartar Emetic may be used instead of Arsenic. 4410. Luminous Paste for Rats, Roaches, etc. — This was formerly quite a favorite rat poison, as it shines in the night attracting the attention of the rats, and at the same time acts as a poison. It is best made by melting Phosphorus 1 ounce in Petrolatum or Lard 1 pound, by means of a water- bath, and while melted and well mixed by agitation in a closely stopped wide-mouth bottle, allow to cool and solidify. This may then be mixed with Sugar 1 pound, and Flour 1 pound, or sufficient to make a stiff mass. A better Luminous paste is made with Arsenic, Luminous paint (made without Turpentine) and Sugar, each, one part, well mixed together. 441 1. Mosquito or Black Fly Preventive. — Hunters and fishers who go in the woods during the summer are much annoyed by flies and mosquitoes. The following preparation is for rubbing on the hands and face to keep them off. Petrolatum 3 ounces, Paraffin % ounce, Oil Tar 2 ounces, Oil Penny- royal 1 ounce, Carbolic Acid 2 drachms. Melt the solid ingredients together and when nearly cold enough to begin to solidify incorporate the other ingre- dients. 4412. To Prevent Flies from lighting on marble or glass. — Put a few drops of Oil of Wintergreen or Pennyroyal on a damp sponge and rub over the surface ; they will not light where this is done, but it must be repeated every 4 hours or so. 4413. Other Poisons. — For potato bugs Paris Green or London Purple seem to be the most successful. The same are also used for coddling moths, and curculio on trees and shrubbery. For liqe on plants Insect Powder is good, but washing with a spray of Whale Oil Soap suds seems to be the most effective. For squash and cucumber bugs, Calomel is used. FOODS. A few preparations arc known as foods for various purposes, as Baby Food, Infant Food, Plant Food, Egg Food, etc. Tin- follow- ing an- some of the principal popular preparations. 4414. Infants and Invalids Food.— These foods are prepared from various grains in various ways ; the object being to secure in them the most valuable constituents of the food, and to present them in the form most 1172 MISCELLANEOUS FORMULAE. readily digested. To this end the grains are variously treated, by malting, removing some of the less valuable constituents, concentrating, etc. As these processes require expensive machinery and experience, they are not adapted to the uses of druggists, and are, therefore, not given here. 4415. Plant Food. — For making plants grow and blossom, the following are used : Sulphate of Ammonium 4 ounces, Sal Nitre 2 ounces, Sugar 1 ounce, Hot Water 1 pint. Mix, dissolve and keep in a well-stopped bottle. A little is added to the Water used for plants. Another formula is Nitrate of Potas- sium 2 parts, Carbonate of Calcium (Precipitated chalk), Chlorate of Sodium, Phosphate of Calcium, each, 1 part, Silicate of Iron 3 parts, Water 20 parts. Mix. INKS, BLUINGS AND BLACKINGS. A great variety of Inks, Bluings and Blackings are found on the market. The following formulas make good preparations of this kind. It must be remembered, however, that there are many quali- ties of Anilines and other substances used in making inks, etc., which have the same name, but are of different degrees of excel- lence. The best should always be chosen. In the limited space only a few formulas can be given, but they will be sufficient. Inks. 4416. Fine Black Ink Aniline.— Negrosine (Black Aniline crystals), % ounce, Dextrin y 2 ounce, Corrosive Sublimate 2 'grains, Water 2 pints. Dis- solve the Negrosine in a pint of hot Water. Dissolve the Dextrin and Cor- rosive Sublimate in the remaining pint of Water and mix the solutions. This ink flows freely, is always black and does not mold. By using a less quan- tity of Aniline a very good ink may be made, but is not so black. 4417. Fine Red Ink Aniline. — Eosine Aniline 180 grains, Water 2 pints. Dissolve the Eosine in the Water. This is a bright, brilliant, fiery Red Ink. It is put up and sold as " Carmine Ink," but is much better and cheaper than it. 4418. Fine Violet Ink. — Aniline — Violet Aniline 120 grains, Alcohol }4 ounce, Dextrin ]4. ounce, Hot Water 2 pints. Put the Aniline in a bottle with the Alcohol and add the hot Water in which the Dextrin has been dis- solved. Different shades of Violet, ranging from reddish to blue, may be obtained and various shades of ink may be made. The letters B and R signify the proportions of Blue and Red used ; the " blue shades " are pre- ferred. MISCELLANEOUS FORMULA. 1173 Perfumed Violet I?ik was formerly just the thing but has now gone out of fashion, It may be made by adding % to i drachm of Bulk Perfume to a quart. Other perfumed inks may be made in the same way. Other Aniline Inks may be prepared in the same manner as the foregoing. 4419. Brown Ink.— )A ounce Brown Aniline, )i ounce Dextrin, 1 Quart Hot Water. 4420. Blue Ink.— Water Blue Aniline i l / 2 drachm, Dextrin % ounce, Hot Water 2 pints. 4421. Green Ink. — Green Aniline 2 drachms, Dextrin % ounce, Hot Water 2 pints. 4422. Maroon Ink. — Mix equal quantities of Red, Blue and Black Inks. 4423. Purple Ink.— This is made like Violet Ink. It is in fact the same as the bluish violet. 4424. Red Aniline Ink.— This may be made from Red Aniline (Fuch- sine) y z ounce, Alcohol 2 ounces, Dextrin }£ ounce, Hot Water 2 pints. It is not so good as the Eosine Red Ink. Scarlet Aniline Ink may also be made from Scarlet Aniline. 4425. Yellow Ink.— Picric (Carbazotic) Acid 2 drachms, Hot Water 2 pints. 4426. Black Ink, Logwood — School Ink. — Extract of Logwood 3 ounces. Bichromate of Potassium 3 drachms, Hydrochloric Acid 4 fl.drachms, Water 1 gallon. Boil the extract with the Water and Bichromate of Potassium in 1 quart of Water until dissolved, add the Hydrochloric Acid to the balance of the Water, and mix the solutions while warm. This ink flows nicely and has a good color. 4427. Blue Ink.— Soluble Prussian Blue (Laundry Blue) x /z ounce, Dex- trin X ounce, Hot Water 1 pint. Mix and dissolve. 4428. Carmine Ink— True. — No. 40 Carmine %. ounce, Water of Am- monia 1 ounce, Dextrin % ounce, Water 1 pint. Rub the Carmine to a pow- der, then with the Water of Ammonia, then with the Water gradually added, and dissolve the Dextrin in the solution. Red Ink made from Eosine Ani- line is much better. 4429. Japan Ink.— This may be made by boiling Borax 3 drachms, Shel- lac 1 drachm, Sugar 2 drachms, for one hour, in a pint of Water, then strain- ing the solution and dissolving in it # ounce Xegrosine or Black Aniline. This does not flow as freely as other inks, but is very black and glossy. Black Gloss Ink may be made from any good Black Ink by adding to it Gum Arabic and Sugar or a strong solution of Shellac and Borax as above. The very finest Japan Ink may be made by dissolving tine India Ink. by rub- 1174 MISCELLANEOUS FORMULAE. bing it with the solution of Shellac as above, made until it is of the proper consistence and color. Other colored inks may be made gloss inks in the same manner as is here described. 4430. Liquid India Ink. — This is prepared from Stick India Ink by rub- bing it down with Water on a plate or other glazed surface until an ink of the proper shade and consistence is obtained. The finest Stick India Ink is prepared from the finest lampblack made into a paste with an infusion of certain native albuminous seeds of China or Japan, and then moulded in sticks. The more common kinds are made up with glue gelatine, etc. 4431. Violet Black Ink — Violet passing to black. — Extract of Log- wood 3 ounces, Bichromate of Potassium 3 drachms, Alum 2 ounces, Lime Water 1 pint, Water of Ammonia 8 ounces, Commercial Hydrochloric Acid, by weight, 1 pound, Iron filings or old scraps of nails 1 pound, Gum Arabic 3 ounces, Water 1 gallon. Boil the Logwood Extract and the Bichromate of Potassium in one quart of Water until dissolved, add the Alum previously dissolved in 1 quart of hot Water, then add the Lime Water ; then the Water of Ammonia; stir thoroughly and gradually add the Hydrochloric Acid with constant stirring, then add the remainder of the Water in which the Gum Arabic is dissolved, and pour the mixture upon the scraps of Iron in an open vessel or crock. Let stand several days and decant. 4432. Writing Fluid. — Blue-Black. — Apello Nutgalls, coarsely ground, 1 pound, Sulphate of Iron, copperas, 5 ounces, Gum Arabic 4 ounces, Boric Acid y* ounce, Extract of Indigo 1 ounce, Picric Acid 1 drachm, Water suffi- cient to make a gallon. Macerate the Nutgalls in one gallon of Water for 12 hours, then boil- in a kettle for one hour and pour off the decoction, add half a gallon of fresh Water to the drugs, and boil again for half an hour and pour off the liquid, press the residue and mix the product with the previous decoc- tion. This will make about 1 gallon of the liquid ; to this, while still warm, add the remaining ingredients and dissolve ; add Water if necessary to make 1 gallon, and after standing 12 hours or more strain through a coarse muslin strainer. This is a good writing fluid, similar to those most popular in the market. Many other similar formulas might be given but this will be sufficient. The color may be varied by using more or less Indigo Extract or Picric Acid. 4433. Copying Ink, Black — For moist sheets. — By adding a little Gum Arabic and Sugar to most any of the foregoing inks, fair copying inks may be made, but the best copying ink may be made from the writing fluid last given (4431), by adding to each pint 1 ounce of Sugar and ]/ z ounce Gum Arabic. An excellent Copying Ink may also be made from the Violet-Black Ink (4430), by adding to each pint )£ ounce each of Sugar and Gum Arabic. This is similar to the popular French Copying- Ink. MISCELLANEOUS FORMULAE. 1175 4434. Colored Copying Inks.— Most of the high-colored Aniline Inks make good copies without the addition of other ingredients. If anything is required, however, l /z ounce of Gum Arabic in a pint is usually sufficient, care must be taken not to make the sheets too wet for copying colored inks, as they are apt to blur. 4435. Copying Inks — For dry paper. — Inks are sometimes wanted for " Dry Copying " as it is termed. This depends upon the ink altogether, which may be made by adding to any of the regular black or colored writing Inks, from 3 to 4 fl. ounces of Glycerin in each pint, or by making the same inks and using 3 ounces of Glycerin instead of the same quantity of Water in a pint. The writing is to be quickly done, without blotting and without shading, and the copy taken at once. 4436. Chromograph or Hektograph Inks. — These inks are designed to be used on the Hektograph or copying pad, by wlr'ch a hundred or more copies or duplicates may be made from one writing. Black, Blue, Red and I 'iolcl may be made in the same manner, but the Violet is most used, because a much larger number of clear copies may be made from it. The formula is as follows : Violet (or other) Aniline x / 2 ounce av., Alcohol ^ fl.ounce, White Sugar % ounce aw, Glycerin 1 ounce aw, Water 6 fl.ounces. Mix the Aniline with the Alcohol, add the Glycerin. Dissolve the Sugar in the Water and add. Of Black Aniline or Negrosine, double the quantity is required. 4437. Indelible or Marking Ink — For marking Linen. — Nitrate of Silver 2>% ounces, Bicarbonate of Sodium \%. ounces, Stronger Water of Ammonia 3^ ounces, Tartaric Acid 1 Y% ounce, Archil 1 ounce, Powdered Acacia 2^ ounces, Soluble Sap Gum (or Dextrin) 1 ounce, Sugar 1% ounces, Water, sufficient to make 20 fl.ounces. Dissolve the Silver and Soda salts, each separately, in two pints of boiling Water and mix the solutions. Allow the precipitate to settle; decant the fluid, and collect the precipitate on a paper filter, wash it with a pint of Water, and, when drained, transfer it to a mortar, add the Acid and mix. When effervescense has ceased add the Stronger Water of Ammonia, and transfer the whole to a bottle containing the Sugar. Now dissolve the Sap Gum or Dextrin in 4 ounces of Water, and 'nil by the aid of heat. Add the Acacia to the mixture, stir until dis- solved, and strain. Add the Ammoniacal solution to this, and make up to 20 ounces with Water. 4438. Indelible Laundry Ink. — Carbonate of Sodium (Sal Soda) 1 ounce av.. Nitrate of Silver ]/ 2 ounce av.. Acacia, powdered, ; , OUtN e av.. Water of Ammonia 1 flounce, Distilled Water 4 il. ounces. Dissolve the Carbonate of Sodium in the Distilled Water and rub with the powdered Acacia in a mor- tar. Dissolve the Nitrate of Silver in the Water <-f Ammonia and mix with the mucilage. Transfer to a flask of double the capacity of the liquid, stop 1176 MISCELLANEOUS FOR.MUL.E. closely, and heat by means of a water-bath to boiling, leaving the stopper loose during the latter part of the operation. 4439. Indelible Ink for Stamp or Stencil.— Negrosine 1 ounce, Tannin 2 drachms, Glycerin 4 ounces, Vanadinate of Ammonium 10 grains. Mix and dissolve. Other colors may be made from other Anilines. 4440. Another.— Asphaltum 1 ounce, Oil of Turpentine 4 ounces, Black Printing Ink 4 ounces, Chloride of Iron y 2 ounce. Mix, dissolve and rub them well together. 4441. Marking Ink for Packages and Boxes. — Extract Logwood 1 pound, Bichromate of Potash 1 % ounce, Hydrochloric Acid 1 % ounce, Dex- trin 8 ounces, Water 1 gallon. Boil the extract with the Water, add the Bichromate of Potash and the Acid, and lastly the Dextrin. Allow to stand and decant. 4442. Marking Ink for Cotton Bales, etc. — Logwood Extract 1 pound, Copperas 10 ounces, Bichromate of Potash \)/ 2 ounce, Hydrochloric Acid 2 ounces, Brown Sugar 1 pound, Water 1 gallon. Boil the extract Math the Water, add the Bichromate of Potash, then the Iron and Acid, and lastly the Sugar. After standing decant. 4443. Marking Inks in Cakes— For brush or stencil. — These are made by rubbing some pigment with Dextrin or Gum Arabic in solution and running the solution into boxes or molds. They are the same as water- color paints, and are to be used by wetting their surface with Water and the brush rubbed over them. Make a thick mucilage of Dextrin or Gum Arabic and stir in the pigment to a stiff paste. For Black, use drop black or ivory black ; for Blue, soluble Prussian blue or ultra-marine blue ; for Green, chrome green ; for Fine Red, rose pink, scarlet lake, or carmine ; for Cheap Red, Venetian red, red lead, etc. 4444. Stamping Inks for Rubber Stamps. — These are prepared from the Anilines by mixing them with Glycerin, }( ounce of Aniline to 1 ounce of Glycerin. Black, blue, green, red, and violet are the anilines usually used for this purpose. The same inks made in this manner may be used for marking pens. Cheaper inks for rubber stamps may be made with drop black, Prus- sian blue, chrome green, rose pink, etc., but they are not in general favor. 4445. Ink Powders. — These are prepared for quickly making Inks by the addition of hot Water. They are usually put up in packages sufficient to make a pint of ink, which requires from a teaspoonful to a tablespoonful of the powder. The following are the colors usually desired : Black, Negrosine in Crystals 1 part, Dextrin 3 parts. Blue, Water Blue Aniline 1 part, Dextrin 5 parts. This may also be made with soluble Prussian Blue 1 part, Dextrin 2 parts. Green, Green Aniline 1 part, Dextrin 4 parts. Red, Eosine Aniline 1 part, Dextrin 1 part. MISCELLANEOUS FORMULA. 1177 4446. Ribbon Inks. — Ribbon Inks for type writers, dating stamps, etc., are prepared by saturating thin silk with a solution of some Aniline color in Glycerin or other vehicle. The colors generally used are Black, Dark Green and J 'iolet or Purple. The solution may be made by dissolving % ounce of the Aniline in a mixture of Alcohol 2 fl. ounces, Water 2 fl. ounces, and Glycerin 4 fl.ounces. The ribbon is saturated with this solution and dried. 4447. Sympathetic Inks.— Sympathetic Inks are those that, when written with, show no writing until something is applied to develop them. They are of no particular use ; but the method of making and using is given below. Black Sympathetic Ink. Write with Tincture of Iron diluted with 10 parts of Water, and develop with a blotter moistened with a solution of Tan- nin or decoction of Nutgalls, or strong Tea. ■ This may be reversed by writing with a decoction of Nutgalls and develop- ing with the blotter moistened with Tincture of Iron. Blue Sympathetic Ink. Write with a solution of Ferrocyanide of Potas- sium, in 20 parts of hot Water. Develop with a blotter moistened with a solution of Iron. The operation may also be reversed. Sympathetic Ink Developed by Heat. Sulphate of Copper and Muriate of Ammonia, equal parts, dissolved in Water. The writing turns yellow when exposed to heat. Lemon juice or the mineral acids diluted, solution of Salt, Saltpetre and many other substances, when the writing is exposed to heat, turn yellow or brown. A weak solution of Chloride of Nickel, mixed with Chloride of Cobalt, turns a beautiful green when exposed to heat. A weak solution of Cobalt, in Nitro-muriatic Acid, becomes green when the writing is heated, and when cooled again, entirely disappears. Copper, dissolved in Muriatic Acid and diluted, becomes yellow when the writing is heated, and disappears when cold. A solution of Acetate of Cobalt, to which a little Nitrate of Cobalt is added, becomes rose color when the writing is heated, and disappears when cold. 4448. Gold and Silver Inks.— Take equal parts of Gold Leaf (or Silver Leafj and Honey. Triturate them in a mortar until perfectly fine, then add about 30 parts hot Water, and triturate. Allow to settle and pour off the Water. Triturate again with fresh hot Water. Allow to settle and pour off as before. Repeat the washing several times until the Honey is all washed out, then dry the powdered Gold Leaf and mix it with Water and Gum Arabic. It must be shaken occasionally while writing. Very fine Bronze may be made into Ink by adding Water and Gum Arabic and shaking occasionally while writing. 4449. White Ink.— For writing on black cards and some other purposes, White Ink is sometimes desired, tl may be made bv rubbing Flake White 1178 MISCELLANEOUS FORMULA. 6 drachms with Acacia, Mucilage 3 drachms, and enough Water to make 1 fl.ounce. It must be shaken up before using. 4450. Horticultural Inks — For writing on Metal. — This ink is pre- pared for writing on metal tags for labeling plants, trees, etc. Blue Vitriol 1 ounce, Salamoniac % ounce, both in powder, dissolve in ]/ z pint of strong vinegar. This may be used on Zinc or Iron strips or steel ; a quill should be used for writing. 4451. Liquid Slating for Blackboards. — Shellac 8 ounces, Lampblack \y 2 ounce, Ultramarine Blue lYz ounces, powdered Rottonstone 4 ounces, powdered Pumice Stone 6 ounces, Alcohol 4 pints. Dissolve the Shellac in the Alcohol, add the other ingredients and mix them well together, apply- quickly with a fiat varnish brush. Ink Erasing Fluid. Fluids for Erasing Ink are somewhat in demand and may readily be made by druggists. 4452. Ink Eraser — One Preparation. — Solution of Chlorinated Soda (Labarraque's Solution) 2 parts, Water 1 part. Mix them. This is to be applied, and as soon as the ink disappears the moisture absorbed with clean blotting paper. Ink Eraser. Two Preparations. No. 1. Hydrochloric Acid 1 ounce, Water 1 gallon. Mix them. No. 2. Solution of Chlorinated Soda 2 parts, Water 1 part. Mix them. To erase the ink apply No. 1 with the end of the penholder, and then directly apply No. 2, and when the ink has disappeared absorb the moisture with clean blotting paper. Bluings. These are made both dry and liquid. The dry Bluings aside from indigo, consist of soluble Prussian Blue, and the liquids are solutions of the same in Water. They may be prepared as follows : 4453. Dry Bluing. — Prussian Blue 4 parts. Oxalic Acid 1 part Powder the Oxalic Acid and mix them well together. If soluble Prussian Blue is used no acid is necessary. This is put up in various ways for the market. 4454. Liquid Bluing.— Soluble Prussian Blue 1 ounce, Oxalic Acid % ounce, Boiling Water 1 quart. Dissolve the salts in the water. Blackings and Shoe Dressings, etc. A great variety of Blackings and Shoe Dressings are found in the market good, poor and bad. We have space only to give two or three good formulas. 4455. Shoe Blacking — French Blacking. — The paste Shoe Blackings of the market are all made in the same general way, by combining some MISCELLANEOUS FORMULAE. 1179 elastic substances with oils, driers, black pigments, etc. The difference in them consists mainly in the quality of the materials used and the skill with which they are compounded. The following will make a good blacking. Dissolve India Rubber, cut fine, 2 ounces, in Cotton Seed Oil 1 pound, by the aid of heat, and add to the solution Ivory Black, in very fine powder, 7 pounds, Molasses 5 pounds, Gum Arabic, in powder, 2 ounces, Strong Vine- gar 22 fl.ounces. Mix them thoroughly and grind the mixture through a paint mill, then add the Sulphuric Acid 1 ]/$ pound, and stir daily for a week or more, or heat gently and incorporate the acid while warm. The use of Sulphuric acid in this blacking is not objectionable as it is neutralized by the lime salts contained in the Ivory or bone black used. 4456. Liquid Paste Blacking. — A liquid Blacking may be made by melting the above and mixing it with good vinegar, say three gallons for the above quantity. This is not like the popular Shoe Dressings on the market. 4457. Shoe Dressing. — Shellac, dark colored, \% pound av., Sal Soda, crystals, 6]4. ounces av., Gum Arabic 4 ounces av., Negrosine (Black Aniline) % ounce av.. Water sufficient to make 1 gallon. Put the Sal Soda in half a gallon of Water and heat to boiling, add the Shellac to the boiling solution and continue the heat for 10 or 15 minutes until all the Shellac has dissolved that will (there will be a small portion undissolved), then add the Negrosine and a pint of Water in which the Gum Arabic has previously been dissolved. When cool, strain and add enough Water to make 1 gallon. This is similar to most of the " patent " Shoe Dressings on the market. It may be made to dry more quickly by adding a little Alcohol. 4458. Bronze Shoe Dressing. — Add to the foregoing %. to ^ ounce of Red Aniline in a gallon, and dissolve by gentle heat. Some other colored anilines will also make a bronze finish. 4459. Patent Leather Dressing. — This is designed to give a finish like patent leather, and is waterproof. It may also be used as a Belt Polish, and for all similar purposes. India Rubber ]4 ounce, Shellac 4 ounces, Camphor y z ounce, Negrosine ]/ z ounce, Wood Alcohol 12 fl.ounces. Dissolve the rubber by heat of water-bath in the Wood Alcohol, then add the other in- gredients and dissolve. 4460. Bronzing Liquid. — Red Aniline 1 ounce, Violet or Purple Aniline Yz ounce, Alcohol 10 ounces, Benzoic Acid ; 2 ' ounce. Dissolve the Anilines in the Alcohol by aid of water-bath, then add the Benzoic Acid and boil 5 or 10 minutes, or until the greenish color of the preparation is changed to a light colored bronze. Apply with a brush or sponge. This may be added to the shoe dressing. 4461. Government Harness Dressing. — Watsfoot Oil 1 gallon, Bayberry Tallow 2 pounds, Beeswax 2 pounds, Beef Tallow 2 pounds, Castor Oil $4 gallon, Lampblack 1 ounce. Melt together the Wax and Tallow, and add the Oils and Lampblack. When thoroughly mixed, strain through muslin. 1180 -MISCELLANEOUS FORMULAE. 4462. Waterproof Blacking.— For greasing boots, making them Water- proof, etc. Neatsfoot Oil 1 gallon, Beeswax 2 pounds, Shellac yi pound, Beef Tallow 8 pounds, Castor Oil 1 quart, Lampblack % pound. Melt and mix them as the preceding. 4463. Harness Polish.— Glue 4 ounces, Vinegar \yi pint, Gum Arabic 2 ounces, Black Logwood Ink yi pint. Dissolve the Glue in the Vinegar by heat of water-bath, dissolve the Gum Arabic in the Ink. Mix the solutions while warm. This makes a jelly which should be dissolved by gentle heat when wanted to use. By adding to this y 2 ounce Nitric Acid it makes a liquid which is always ready for use. The Shoe Dressing (4457) may also be used for Harness Polish. 4464. Hectograph Copying Pad.— Hectograph Copying Pads should be made somewhat softer for winter use than for summer, which can be done by adding a little larger proportion of Glycerin. Good Glue 4 ounces av., Glycerin 16 ounces av., Water 8 flounces. Break up the Glue and soak in the Water for a few hours, then heat by water-bath until melted, and add the Glycerin and heat together for some time to evaporate part of the Water, then strain into a shallow square tin to make the desired shape, and skim with a card to free from bubbles. This is improved by adding 1 ounce car- bonate of barium to the liquid while warm. The writing to be copied is done with Hectograph Ink (4436) and trans- ferred to the pad, sheets of paper are then put on and copies made. 4465. Carbon Duplicating Paper. — Lard 10 ounces, Beeswax 2 ounces, Canada Balsam 1 y 2 drachm, Lampblack sufficient. Melt the Lard, Wax and Balsam together and add enough Lampblack to make of the desired color. This is applied to firm thin paper with a flannel dauber and wiped off with clean rags. POLISHING PREPARATIONS. Among the preparations put up and sold by druggists and others connected with the business are a great variety of Polishes of differ- ent kinds, and for various uses. The following are the formulas for the more important ones : Furniture Polish. For restoring the color or luster of furniture, preparations are designed to be applied with a cloth, and rubbed until dry. 4466. Furniture Cream. — Common White Soap 150 grains, Sal Tartar 60 grains, White Wax lyi ounces, Water 5 fl. ounces, Oil of Turpentine 10 fl. ounces. Melt the Soap in the Water by the heat of water-bath, add the Sal Tartar and then the White Wax. When the Wax is melted, remove from the fire and slowly add, with constant stirring, the Oil of Turpentine, MISCELLANEOUS .EURMUL.E. 1181 mixing them thoroughly while cooling. This is to be applied with a cloth and rubbed down with Canton flannel. 4467. Furniture Polish.— Linseed Oil 6 flounces, Alcohol 3 fl ounces, Shellac 1 ounce av., " Butter " of Antimony 1 Y flounces, Hydrochloric Acid x /z ounce, Oil of Turpentine 5 flounces. Dissolve the Shellac in the Alcohol, and mix with the Linseed Oil and Turpentine, then, having mixed the Hydro- chloric Acid and " Butter " of Antimony, add them to the preparation and mix thoroughly. Apply as the preceding. Glass Polish. For polishing glass, mirrors and bright ware, as silver-plated ware, etc., the following are recommended : 4468. Glass and Silver Polish. — Prepared Chalk 3 ounces av., Alcohol, Water of Ammonia and Water, each, 3 fl. ounces. Mix them by rubbing the Chalk to a smooth paste with the liquids. 4469. Glass Polish. — Calcined Magnesia mixed with Gasoline into a liquid of the consistence of cream is excellent for polishing plate glass, mir- rors, etc. Calcined Magnesia made up into balls with powdered soap is also a good preparation for this purpose. Silver Polishes. The following arc recommended for polishing silver and nickel- plated ware, etc. They make fine polishes that will not scratch. 4470. Silver Polishing Liquid. — Prepared Chalk 1 pound, Crocus Martis 4 ounces. Mix well together and to make up, put 1 ounce of the mixture in a 4 ounce bottle, add 1 ounce of Water of Ammonia and Water enough to fill the bottle. Shake before using and apply with a cloth, then rub off when acid, 159 formate, . . . 151 violet 155 ide 157 hydrate, . . 95 [50 violet, I [oilman's, 155 Antimonium, i55 hydrated oxide, . 151 yellow, .... 155 suiphuratum, . [59 iodide, .... 151 Animal alkali, r , 142 Antimony, . . . nitrate 15' charcoal, . •ji 1 alloys nitris '5' charcoal, purified, 21 1 ami potassium tart [5 e nitrite [« 1 drugs 23 Mark 158 nitrite pearls, . . 152 oil, I tippet's, . . 641 bromide, valerianate, 151 oils 643 butter, . . i' Ann lie alcohol, . 95 150 Anime ;-i chloride solution, 549 Amylene 151 gu'» 724 crocus of, . . . t6o 1206 Antimony, ethiops of [60 Appletreebark, fl. ext 476 Argenti, cyanidum, 172 fluoride, . . . 159 Apricot syrup, . . 850 iodidum, . . 173 glass of, ... 160 Aquse 161 nitras, . 173 golden sulphide. . 160 Aqua ammonia;, 143 nitras dilutus, 174 gray 155 ammonia; fortior, 144 nitras fusus, . 174 iodide 159 amygdalae amarse, 163 nitras mitigatus, 174 liver of, ... 160 anethi, .... 164 oxidum, . . 175 oxide, .... 157 anisi, .... 164 Argentum, . . 172 oxides, .... 159 aurantii riorum, . 164 foliatum, 172 oxyehloride .157 159 camphora?, 165 purificatum, . 172 oxysulphide. . 160 carbolisata, 165 Argols 703 pen-tasulphide, 160 carui, .... 166 Arnica flowers, fl. ex .,468 perchloride, 549 chlori, .... 235 flowers, extract, 443 purified sulphide, 15S chloroformi, . . 166 tincture, . . 885 sulphantimoniate, 160 cinnamomi, 166 glycerite, . . 519 sulphate, . . . 160 creasoti, . . . 167 jelly, . . . 1147 sulphide, . . . 158 destillata, . 167 liniment, 1092 sulphurated, . 159 foeniculi, 167 oil 652 sulphuret, . 15 s fortis 636 plaster, . . . 333 tartrated, . 156 gaultheriae, 168 root, fluid extract 471 terchloride, 160 lauro-cerasi, . 16S root extract, . 443 trioxide, 157 lucise, .... 94S tincture, . . 886 vitrified, . . . 160 menthae piperita;, 169 tooth wash, "37 wine, .... 99S menthae viridis, . 169 Arnotta, . 875 Anti-moth paper, . 1170 picis, .... 169 Aromatic fl. ext., 459 Antiperiodic oint, . 993 pimentae, . 170 bitters, . 437 Antipyrin, . 132 160 phagedaenica, . 596 bitters extract, 436 elixir, .... 284 regia, .... 636 cachous, 435 Anti-rheumatic paper, 230 rosa; 170 confections, . 266 Antiscrobutic syrup, 826 sambuci, 171 cordial, . . . 262 tincture, 949 Aquarium cement, . 1 164 ext. Jamaica gin wine,' .... 1014 Aqueous ext. aloes, 443 ger, . . • 1074 Antiscrofulous elixir, 950 extract cinchona, . 444 ointment, . 993 Antiseptic supposito- fl. ext. bael fruit, 489 powder, 714 ries 786 fl. ext. broom tops, 489 chalk andopiun 1, 715 Antispasmodic tinct. 950 fl. ext. cascara sa- series, . 190 Ants tincture, 949 grada, 490 species or herbs, 75S Aperient, seltzer, fl. ext. goldenseal, 490 spirit of ammonia 762 . . . . 603, "15 fl. ext. hydrastis, 490 tincture, . . 886 effervescing pow- fl. ext. ipecac, 490 vinegar, . 51 1161 ders, .... 715 fl. ext. liquorice, 491 vinegar of opium 54 magnesian water, 869 fl. ext. opium, 49 1 wine, . . 999 1006 magnesian, 603 fl. ext. senega, 491 Arrowroot, 153 Apis mellifica, . 61S fl. extract, senna, 492 Arrow wood, fl. ext. 476 Apium, fl. extract, . 461 fluid extracts, . . 489 Arseniate of ammo Apocynin, 732 tinct. of rhubarb, 934 nium, 149 Apocynum, fl. ext. 46S Arabic acid, . 726 barium, 1S7 Apocodeine, . . . 666 gum, .... 726 copper, . 266 Apollinaris water so- Arabin, .... 726 iron, . . 17 S, 499 lution 868 Aralia comp. fl. ext., 485 iron ointment, 992 Apomorphia, 104 666 hispida, fl. ext., . 473 lead, . . . 698 Apomorphina, 104 666 nudicaulis, fl. ext., 473 sodium, . 17 3, 747 Apomorphine, IC4 666 racemosa, fl. ext.. 473 sodium ointment, 992 Apomorphince h y - spinosa, fl. ext., . 473 manganese, 615 drochloras, . 105 spinosa tincture, . 947 mercury, 531 Apples, ferrated ex- Arbor vitse, fl. ext. . 462 potassium, . 711 tract, . . . 446 tincture, 947 Arseniates, 177 tincture, . . 90? Arbutin, .... 732 Arsenite of potas essence or ext. 428 Arbutus, trailing, fl. sium solution, 55o oil, 151 extract, . 474 Arsenites, 177 Apple, bitter, fl. ext. 474 Archil, .... 876 Arsenic, 177 syrup S50 Areca catechu, fl. ext 473 acid, . . . 177 INDEX. 1207 Arsenic and iodide of Aseptol ii*r Australian cholera mercury elixir, . 2S5 tooth-ache remedy, 1121 specific, 1054 and mercury io- Ash, black, fl. ext., 474 Ava kava, fluid ext. 462 dide, solution, . 550 prickly, fl. ext., . 460 A vena sativa, fl. ext. 46r and stry chnine prickly, southern, concentrated tinct. 1129 elixir. 285 fluid extract, . 469 Avens, European, fl. bisulphide, 179 wafer, fl. ext., 469, 4S7 extract, . . . 474 bromide, . . . 179 white, fl. ext., 474 water, fluid ext. . 474 chloride, . 179 Asiatic tincture for Azedarach, fluid ext. 461 chloride solution, 547 cholera, . . . 1054 Azote, ..... 635 elixir, .... •285 Asimina triloba, fluid iodide 178 extract, . 465 oxide, .... 177 Asphalt, .... 694 B trisulphide, 179 Asphaltum, . . . 724 white, .... 177 liquid, .... 724 Babbitt-metal, . . 156 Arsenical cerate, 225 Asparagin, 732 Baby soother, . . 1113 ointment, cancer, 992 Asparagus, fl. ext. . 473 Baccharis pilularis, fl. ointment, mild, . 992 Aspidium, fl. ext. . 461 extract, . 465 ointment, hospital, 992 oleo-resin, . . . 661 Bael fruit, fl. ext. . 4S9 soap 743 Aspidosperma, fl. ext 405 Baking soda, . 743 Arsenicum, . 177 tincture, 947 powder, . . . 1167 iodide, .... 178 Asthma cure, . . 1030 Balm, eucalyptus, . 1032 Arsenii iodidum, 178 cures 1030 Gilead 1S2 Arsenious acid, . 57 177 inhalant, . . . 1030 Gilead buds, tinct. 946 acid solution, . 547 mixture, . . . 628 Gilead, factitious, 133 anhydride, . .57 177 pastiles, 1031 Gilead, fl. ext., 462 ,437 oleate, .... 65S relief, .... 1030 lemon, fl. ext., 475 oxide, .... 177 remedies, . . . 1029 magic, .... 1032 Artificial fruit essen- remedy, . . . 1029 magnetic, . 1032 ces 427 Asthmatic cigarettes, 1031 mint oil, . . . flavors 427 Astragalus, . 727 pain cure, . 1032 gum 271 Astre puniceus, fl. ext • 478 ready, .... 1033 Artimisia abrota- Astringent ointment, 993 of a thousand flow- num, fl. ext., . 468 suppositories, . . 735 ers, .... 1 1 36 frigida, fl. ext., . 468 tinct., Copeland's, 949 spirit 769 syrup compound, 826 Atomizers, steam, . 000 universal, . 186 vulgaris, fl. ext., 468 Atropia, .... 105 wizard C033 Arum triphyllum, fl. sulphate, . . . 106 Balms or panaceas, . [ 03 1 extract, . . . 487 Atropin, .... 732 Balmony, fl. ext., . 473 Asafetida, . . . 728 Atrophia 105 Balsam anodyne, 1034 and magnesia mix- Atropin. e sulphas, . 106 calaba l8i ture, .... 625 Atropine, .... 105 "la, 663 elixir 285 discs 542 l.i, factition, 183 emulsion, . 408 elixir, .... 286 canker, .... 1034 fluid extract, . . 494 ointment, . . . 972 Carpathina, 1 sj liquid extract, 494 oleate 657 caustic, Go m- mixture, 621 sulphate solution, 551 baulfs, . . . l-U oil 052 Attwood's patent Al- China, varnish, . plaster cohol 37 copaiba, ■ syrup 824 Aubergier's syrup of copaiba factitious, is; tincture, . . . S87 lactucarium, 806 1I1. 1 reduced, . [83 tincture etherial, . 952 Aural suppositories, 7-o copaiba tincture, . 946 Asarum, fl. extract, 46] Aurantii, amari, fl. ext. 4'''' cough io6a 1 ompound syrup, 826 dull is, fluid ext. . 47.; flora vanti, . tin 732 elixir fir, ... 182 . 663 662 Aurantium infusion, fir hark. fl. ext., . uuti, fl. infusion comp. fir emulsion, l"7 . 46] ■ sodii cblori- fir oil, . curassavica, fl. ext. ilnin 179 tir tincture, . . 346 incamata, fl. ext., 461 Aurum C7 1 . 890 tuberosa, fluid ex- Australian bitter Goulard's, 185 tract, . . 461 ,487 hark, fluid <-\t. J6l 1- 120S INDEX. Balsam guaiacum, . 1S5 Barbers' shampoo, ' . 11 44 Beberia sulphate, 107 guriun, . . 1S2 , 663 Barium, . 1S7 Beberina, . 107 honey, .... 1S4 acetate, . . 1S7 Beberinse sulphas, 107 Hungarian, 1S2 , 663 arseniate, . . 1S7 Beberine, . 107 Japan varnish, 182 benzoate. . 1S7 Beberine sulphate, 107 life, Hoffman's, . 62S bromide. . 187 Beech American fl. e x- 474 Locatelle's, 1035 carbonate, ■ . . 1S7 Bed bug poisons, 1 1 70 lung 1067 chloride . iSS Beef coca and iroi l Mecca 1S2 chromate, . . iSS tonic, 111S Mecca factitious. . 1S3 hydrate, . 188 and coca tunic, 1 1 1 s Metz 1S5 iodide, . . . iSS elixir, 2S6 nervine, 994 nitrate, . . . I8S essence, . . 416 ointments. . 992 oxalate, . . IS8 extract, . . . 416 Peckham's, 1036 oxides, . . iSS and iron elixir, 2S6 pectoral, 1S5 peroxide, . IS8 iron and cinchom I Peru 181 sulphate, . iSS elixir. 2S7 Peru emulsion, 40S sulphide, . . iSS iron and cinchom I Peru factitious, 1S4 sulphite, . iSS wine, 1008 Peru ointment, 992 Bark extract, . • 444 juice, 416 Peru reduced, . 1S4 Barks, . . . 20 peptone, . . 670 Peru syrup, 824 Barley malt, fl. ext. 475 tea extract, hot, 867 Peru tincture, 947 sugar, . . • 735 wine, 1007 Rackasira, . 182 Barometer paper, . 240 wine and iron, 1007 Riga, .... 1S2 Barosmin, . 73 2 Beer, birch, . 425 saturnine, . 185 Basham's mixture , • 624 birch extract, 425 sulphur, . . . 186 Basic mercuric sul- Ottawa, . . 425 Thibault's, . . J 035 phate, • 530 Ottawa, extract, 425 tolu, 1S1 Basilicon oint. , 221,987 Peruvian, . 425 tolu factitious, 184 black, . . • 992 Peruvian extract, 425 Turlington's, . 1035 Bassorin, . • 727 root, . . . 427 turpentine, . 182 , 1S6 Bateman's pect oral spruce, . . . 427 universal, . 1S6 drops, . 1 106 spruce, extract, 427 vegetable, healing, 1035 lotion, . . • 597 Beeswax, . 214 viride, .... 1S5 Battery solutions or Beet-root sugar, 734 Balsamic comp'ds, . 1S4 fluids, . . • 5S6 Behn oil, . . . 642 mixt. Hoffman's, . 628 Batteries gravity, • 586 Belladonna abstract 47 tooth wash, "37 high resistance , • 5S6 dialysate, . Balsams, . 20, 180, 1033 Leclanche, . . 5S6 elixir, 287 factitious, . 183 medicinal, . • 5S6 extract, alcoholic 443 natural, true, . 1S1 Battley's sedative so- juice, 775 proprietary, 1033 lution, . 5S9 leaves, fl. extract 468 Balsamodendron Baumes, . . . 1S0 liniment, . . 543 mukul, .... 663 Bayberry bark syi up, 589 oil" .... 640 myrrh a, 729 fluid extract, . 462 ointment, . 072 Bambor, brier fl. ext. 476 oil, . . . . 662 plaster, . 384 Banana ess. or ext., 429 tallow, . . • 215 root, fluid extract, 459 syrup, .... 851 Bay essence, . . 410 syrup, . . . 824 Bandoline, 1131 hair grower, • 1 143 tincture, '8S9 rose, .... 1131 hair lotion. • "43 Belhvort fl. extract 469 quince, .... 1131 laurel fluid extr act, 469 Belt polish, "79 powder, .... 1131 oil, . . . • 649 Benjamin,' 1S2 Baneberry, red, fl. ext ,461 rum, . . 770, I 144 Benne fluid extract 469 Baobab, fluid ext., . 468 wax, 215 oil 639 Baptisia, fl. ext., 461 . 4S7 Bdellium, 663, 729 Benzene series, . 190 tincture, 947 Beach-nut oil, . 662 Benzin, 1S9 Baptisin, .... 732 Beach's ointment • 994 jelly, . . . 1169 Barata, caustic, . . 188 Bearberry fl. extr act, 472 petroleum, . 189 water, .... 18S infusion, • 538 Benzine, . 671 Barates, . . . 1S7 , 188 Bear's foot fl. ext. ,465,4S7 fragrant, 1 168 Barbadoes tar, 655 grease, . . 641 Benzinum, 189 Barberry, fl. extract, 468 oil, . . . . 641 Benzoate ammonium 145 Barbers' pomade, 1 144 Bebeeru fl. extrac t, • 465 barium, . 187 INDEX. 1209 Benzoate iron, . . 5 11 lithium, . . . 593 manganese, . . 615 sodium 747 Benzoated tincture opium Benzoates, . . . 182 Benzoic ether, . . 78 acid, . . . 57. acid lozenges, . . 960 acid troches, . . 960 aldehyd, ... 96 Benzoin 182 Benzoinated lard, 76, 973 ointment, ... 76 petrolatum, . . 973 Benzoin comp. fluid extract, .... 494 fluid extract, . . 494 comp. liquid ext. , 494 liquid extract, . 494 oil 654 ointment, . . . 973 tincture, . . . 889 tincture comp., . 890 svrup 824 Benzol, . . 1S9, 694 Benzolum, . . Benzoyl 182 sulphonic-imide, . 736 Benzyl-aldehyd, . . 645 benzoate, . . ■ I Si cinnamate, . . 1-1 Berberia, ... Berberina, . . . 10S Berberina; hydrochlo- ras, . . . • 109 Berberince sulphas. Berberine, . 1 and iron elixir, . 288 bismuth and iron elixir, . . . 2S7 hydrochlorate, . 109 sulphate, ... 109 Berberis aquifolium fluid extract, 468, 4-7 vulgaris, fl. ext., . 465 mot essence, . 4 I,J esse, for perfumes, 1152 oil wild, fluid ext., . 469 . . . 20 Betel nut fl ext., 473 Beth root, fl. ext., . 462 Betin dca, fl. ext., Betony, fl. ext., . . 468 Betula lenta, fl. ext.. 473 Bibiria 107 Biborate sodium, 1 Bicarbonate am'nium, 149 issiom, . . . 7" 1 Bicarbonate sodium, 745 sodium troches, . 966 Bichloride ethylene. Bo, B3 mercury, . . . 526 Bichromate am'nium, 149 lead, 698 potassium, . . . 702 Bidens bipinnati fl. extract, . . . 473 Bimeconate morphine, 122 Bin-iodide mercury. . 527 Bin-oxal'e potassium, 712 Bin-oxidide nitrogen, 635 Birch beer, . . . 425 beer extract, . . 425 beer syrup, . 425. -51 fluid extract, . 473 oil 652 tar, 694 tar oil, .... 652 Birth root, fluid ext., 462 Bismuth, .... 191 alloys, .... 191 amalgam, . . . 191 ammonium citrate, 194 ammonium citrate solution, . . . 570 basic chloride, . 196 bromide, . . . 196 carbonate, . . . 192 chromate, . . . 197 citrate, .... 193 elixir 2SS glycerite, . . . 519 hair dye, . . .1141 hydrated oxide, . 195 and iron elixir, . 289 iron and strychnine elixir, . . . 289 lactate, . . . . 197 liquor lozenges, . . . 961 nitrate 197 oleate, . . . 65S oxalate, . . 197 oxide, .... 194 oxycarbonate, . . 192 oxychloride, . . 197 oxynitrate, . . . 196 purified, . . . 192 salicylate, ... I r solution, 5 : ' sub-carbonate, I . : sub-chloride, . 196 sub-nitrate, . . [96 tannate, . . tartrate, . . , 1 C terchloride, . . i<)~ tris-nitrate, . . i<;7 valerianate, . . I<)7 Bismuthi carbonas, . [92 citraa 193 Bismuthi et ammonu citras, . . . . 194 oxidum, . . . 194 sub-carbonas, . . 195 sub-nitras, . . . 196. Bismuthic acid, . . 195 anhydride, . . . 195 oxide, .... 195 Bismuthum, . . . 191 puriricatum, . . 192 Bistort fluid extract, 473 Bistorta, fl. ext., . 473 Bisulphate of arsenic, 179 potassium, . . . 711 quinine, . . . 126 Bisulphide carbon, . 212 potassium, . . . 711 Bisulphite sodium, . Bitartrafepotass'm, 703 Bitter almond essence, 410 almond oil, . . 645 almond oil, artifi- cial, . . .190, 645 almond water, 163 apple, fl. ext., . 474 bugle, fl. ext., 47 r elixir 3S0 orange peel tinct- ure, . . . 8S7 polygala, fl. ext., . 476 root, fluid ext. , . 46S tincture, . . . 8S5 wine of iron, . 1002, 100S, 1014 Bitters, aromatic, . 437 angostura, . . . 436 blood, .... 1040 burdock blood, . 1040 cinchona, . . . 438 extracts, . . . 436 extract aromatic, extract, angostura, 436 extract, Boker's, . 437 extract orange, . 43; extract, Peruvian, 438 extract, stomach. 438 extract, Stoughton, 430 ext. wild cherry, . 439 ( lerman liver, . .104] hop 1037 iron 1038 iron tonic, . . . 1039 iron wine, . 1040 jaundice, . . . i"42 laxative, . . . 1042 malt 'I' mandrake, . . 1042 orange 437 Peruvian, . . 438 plantation, . . 1038 poor man's. [04a proprietary, . . 1036 1210 IXDI'.X. Bitters in powder, . 1043 Blood dragon's, . 725 Boro-glyceride, . • J 99 restorative wine, . 1014 flower, fl. extract 46S Boron • *97 rheumatic, . nog and liver syrup, 1026 Borotartrate of potas stomach, . 43S, 103/ orange syrup, . 860 sium, . • 7ii vinegar, 1043 proprietary, 1044 Boswellia, . • 730 wahoo, .... 103S purifiers, 1044 Bottle wax, . . . 217 wild cherry, . . 439 purifying tea, . 1045 Boundon, fl. ext., . 401 Bittersweet, fl. ex. 47] ,474 root, fl. extract, 460 Bouquet essence, • 1 1 55 false, fluid extract, 473 root, fl. ext. acetic 4 S3 Box, fluid extract, . 468 syrup 823 root syrup, . S23 Brandy, • 771 Bittern, . . 200 , 588 root tincture, . 937 artificial, . 11S7 Bitumen, fossil, . . 724 root tincture, acet mixture, • 771 Bixa, orellana, S75 ous, . . . 949 syrup, . . . . S51 Black antimony, . 158 root tincture com Brass . 26 Blackberry carmina- pound, . . 949 Brassica, . • 639 tive, .... 1045 Bloom of roses, . "33 Brayera, fluid ext., • 459 cordial, .... 1069 Ninon, face powde -.1135 infusion, • 534 elixir, . . 290 youth, . 1133 Brazil-nut oil, . 662 essence or extract, 429 Blondine, . 533 Brimstone, . 780 fluid extract, . . 467 Blueberry essence horse, . 780 fl. ext. compound, 4S1 extract, . . 430 Britannia metal, . . 156 root syrup, S23 syrup, . . . 857 British blackdraugh t, 627 syrup, . . . 81^1 , 850 Blue chemic, . 877 gum, . . . • 271 syrup aromatic, . S26 flag extract, 447 oil • 653 Black cherry essence flag, fl. extract, 464 Bromacetic acid, . 201 or extract, . . 429 flag tincture, . 947 Bromal, . . . c )6, 200 cohosh elixir, . 290 litmus, . 24S hydrate, . . . 200 cohosh elixir com- mass, 617 Bromates, . . 201 pound, . 291 ointment, . 978 Bromic acid, . . 201 cohosh fl. extract, 460 pill, .... 617 Bromide aluminium , 140 cohosh fl. extract Prussian, . 512 ammonium, • 145 compound, . 482 show bottle, . 251 ammonium elixir, 291 cohosh tincture, . 899 soluble, . 512 ammonium syrup 833 cohosh tincture stone, 265 antimony, . • 159 compound, 949 vitriol, . 265 arsenic, . • 179 currant essence or Bluing, . . 512 , 1178 barium, . . 187 extract, . 429 Boerhaave's anti-astli - bismuth, . . . 196 draught, . . 536, 627 matic elixir, 3S0 cadmium, . • 203 draught British, . 627 visceral elixir, 3S0 calcium, . . 205 drop, British, . 54 Bog bean, fl. ext., 475 calcium elixir, . 292 ink, . . 1172 to 1 1 76 Boker's bitters, ext., 437 chloral elixir, . • 294 Japan, .... 724 Boldo, fluid ext., 461 chlorine, 201 pepper oil, . 661. tincture, . . 947 chromium, . 239 pitch, .... 694 Boldus, fluid ext. , 461 copper, . 266 plaster, .... 386 Boletus laricis, fl. ext ., 461 gold, . . . 180 root, fluid ext., 472 Bone-black, . 211 iodine, . 201 Blacking, French, . I17S oil, ... 21 1,641 iron, 5ii harness, 1179 spirit, 211 iron elixir, . 292 Bladderwrack, fl. ext. , 474 Boneset, fl. ext., 47 1, 474 iron syrup, 799 Blandine, .... 1 1 34 Bonjean's ergotin, 446 iron syr. (tasteless , 831 Blazing star, fl. ext., 475 Borage, fluid ext., 473 lead, 69S Bleiwisspflaster, . 385 Borago, fluid ext., 473 lithium, 593 Blessed thistle, ext. 444 Boracic acid, . . 5 7, 198 magnesium, 601 thistle, fl. extract, 473 Borate of ammonium . 149 mercury, 531 thistle tincture, 947 potassium, . 711 morphine, 122 Blistering cerate, 219 sodium, . 19 3, 748 morphine elixir, 293 collodion, . 242 Borax, ... 19 3, 74S morphine syrup, 831 liquid 553 glycerite, . . . 51S nickel, . . . 634 paper, .... 228 honey, . 618 potassium, . 703 Blister plaster, 219 Boric acid, . . 5 7, 198 potassium elixir, 293 Blood bitters, 1040 acid ointment, 969 potassium elixi cleanser, 1044 Borocitrate of lithium , 595 compound, . 294 INDEX. 1211 Bromide of potassium Buchu tincture, . S91 syrup, . . S33 Buckbean extract, . 45o quinine, 126 fluid extract, . . 475 quinine syrup, 831 Buckeye fluid extract, 468 quinine and mor Buckhorn brake, fl.ext 475 phine syrup, S32 Buckthorn berries, fl. quinine elixir, . 295 extract, . . . 476 quinine, morphine bark, fluid extract, 477 and strychnine cordial, .... 1049 syrup, '. . S32 elixir, .... 325 salts ointments, 992 extract, .... 449 silver, . . . 176 syrup 811 sodium, . 749 Buds 20 sodium elixir, . 295 Bugle bitter, fl. ext., 474 sodium syrup, S33 weed, fl. ext., 475 4S7 strychnine anc 1 Burdock blood bitters, 1040 morphine syrup 832 root, fluid extract, 475 strychnine, iron seed, fluid extract, 473 and quinine syr S33 Burnt sugar coloring, 245 strychnine syrup, S32 elixir 33i sulphur, . . 7-i Burgundy pitch, . 694 zinc, . . . 1015 pitch plaster, . 3SS Bromidia, . . 2g_ , 1 IOO Burweed spiney, fl. ex. 469 Bromides, 200 Butter 202 541 compounds, IIOI artificial, 202 Bromine, . . . 200 Butterine 202 chloride of, 236 1 Sutter color, . 249, iifS~ ointment, . 992 cacao, .... 640 Bromo-chloralum, 536 antimony, . 549 Bromoform, . . 200 nutmeg, 639 Bromum, . . . 200 Butternut, American Bronze, . 2b 4 fluid extract, . 465 aluminium, 137 bark, extract, . . 447 phosphor, . . . 264 European, fl. ext. 475 Broom juice, . . • 776 Button snakeroot, fl. tops, fl. ext. aque - extract, . . . 475 ous, . . 489 Butyl 85 201 Brown mixture, . . 624 alcohol 35 mixture improved . 625 chloral, . . . 96, 201 ointment, . • 992 chloral elixir, . . 314 i ud's anti-epi chloral-hydrate, . 201 leptic mixture, chloral hyd'te elix. 321 Brucinc, . • 131 Butylic alcohol, . 201 Brust pulver, . . • 7"' Butyrate of amyl, 15 , 201 thee, • 759 Butyrate of ethel, . 201 Bryonia, ll. ext, . . 401 Butyrates 201 tincture, . . . 8go Butyrum 202 Bryony, lluid ext., V Butyric acid, . 201 spirit compound, ■ 772 ether, ... 78 , 201 Buchu compound, . tog] Butyrin ._., , 2 elixir, . . . . 296 Buxine 107 elixir compound, . 296 Buxus sempervirens extract, distilled, • l--- fluid extract, 468 fluid extract, . . 466 ll. ext. compouni , 1--' infusion, . 537 c juniper elixir, juniper fl. extrac , 482 Cabbage, skunk, ll. ex • 4»S oil .... 1 Pareirabravaelbt r, 296 c; Prariera brava, t . 1 butter, . . 640 extract, . 48a . . •j -j 5 Cacao fluid extract, . 476 Cachinca, fl. extract, 46S Cachou flavor, . . 435 Cachous aromatic, . 435 Cactus tincture, . . 949 fluid extract, . 461, 4S7 Cade oil, .... 648 Cadmium, . . . 203 bromide, . . . 203 carbonate, . . . 203 chloride, . . . 203 iodide, .... 203 nitrate 203 ointment, . . . 992 oxide, .... 204 sulphide, . . . 204 sulphate, . . . 204 Caesium 204 Caffea, fluid extract, 473 tosta, fluid extract, 473 Caffeina no Caffeinas citras, . . no Caffeine no citrate, ... no citrate elixir, . . 317 ointment, . . . 992 Caff-iodoform, . . 539 Cajuputene, . . . 646 Cajuput oil, . . . 646 spirit, . . . . 7114 toothache remedy, 1 1 2 1 Calaba balsam, . . 181 Calabar bean extract, 449 bean fluid extract, 462 bean tincture, . . 931 Calamine, . . . 1016 cerate 223 ointment, . . . 974 Calamus draco, . . 725 essence, . . 410 extract 444 fluid extract, . . 459 oil, 646 syrup, . . .823, tincture, . . . 89] ( !ali ii bromidum, . 205 carbonas, pi tatus, . . . 205 chloridum, . . hydras, . . . hypophosphis, . pbosphas praecipi- tatus, . . . 207 sulphurata, Calcined magnesia, . magnesia, heavj . - Calcium 204 bisulphide, . . . 210 bromide, tonate, . carbonate precipi- tated, . . . 20s 1212 INDEX. Calcium chloride, . 206 chloride solution, 55i fluoride, 209 hypophosphite, 207 hypophosp'e syrup. 834 iodate, .... 210 iodide, .... 210 iodide elixir, . 336 iodide syrup, . 33S iron lactophosph'e syrup, . 841 lactophosph'e sol'n, 573 lactophosph'e syrup 841 lactophosph'e syrup 797 oxide 20S pentasulphide, 210 phosphate, acid, . 753 phosphate, neutral, 753 phosphate solution, phosphate syrup, . phosphate precip'd, 207 sulphate, . . . 210 sulphide, . 209 210 sulphocarbolate, . 782 Calendula, fl. ext. , . 46S glycerite, . =;20 tincture, 891' California laurel, fl. ex. 476 Calisaya cordial, 261 bismuth elixir, 299 bismuth and strych- nine elixir, . 299 comp'd elixirs, 29910311 elixir, . . . 297 29S elixir, ferrated, 300 elixirs, other, . . 3 11 fluid extract, . . 477 iron and bismuth elixir's, . . 300 304 iron elixir's, 300, 302, 304, 310 ,3n iron and strychnine elixirs, 301, 303 305 iron and strychnine wine 1009 phosphate syrup, . 852 syrup, .... 852 wine 1008 Calomel T-: and jalap powder, 720 ointment, . 9S2 Calumba extract. 444 infusion, . . . 537 tincture, . . . 892 Calx 208 chlorata, 209 chlorinata, . 209 Calycanthus floridus fluid extract, . 465 Cambogia, 720 Camphor, .... 727 anise, .... 646 Camphor cerate, . 21S chloral 234 chloral glycerite, . 520 chloral, tooth-ache cure 1 1 20 cream H33 elixir compound, . 346 etherate, ... Sr ice, 1193 ice, carbolated, . 11 46 ice with glycerin, . 1146 ice with glycerin carbolated, . . 1147 Japanese, . . . 649 julep 1000 liniment, . . . 544 liniment, ammon'd, 544 liniment, comp'd, 544 mixture, Hope's, . 62S monobromated, . 727 monobromated elix. 311 ointment, . . . 992 peppermint, . . 649 plaster 392 oil 652 spirit, .... 765 tincture compound, 893 water, . . . . 165 wine, .... 1000 Camphorated glycer- ine jelly, . . 1 147 carbonate of lead ointment, . . 9S5 oil, . . ' . . . 544 soap, .... 743 tincture of opium, 92S ' tooth powder. . . 1139 Canada balsam, . . 182 balsam emulsion, 407 balsam, factitious, 163 balsam syrup. . . S24 pitch 694 pitch plaster, . . 388 snake root oil, . 652 turpentine, 182, 663 Canarium commune, 663 Cancer plaster, . . 392 root, fluid extract, 474 Canchalagua, fl. ext., 474 Candlenut oil, . . 662 Candied aromatics, . 260 sweet flag, . . . 260 Candleberry, . . 216 Cane sugar, . . . 734 Canella, fl. extract, 461 oil, 652 tincture, . . 946 Canelle alcoolat, . . 453 Canker lettuce, fl ex. 476 balsam 1034 Cannabis Indica ext., 444 Indian tincture, . 893 Cannabis sativa, fl. ext., . . 461, 4S7 Indica fl. extract, . 459 Cantharidal collodion, 241 Cantharides cerate, . 219 etherate, ... 81 fluid extract, . . 461 fl. ext., etherial, . 493 extract, cerate, . 220 liniment, . 553, 544 oil 640 ointment, . 974, 992 paper 227 plaster, . . .219, 3S4 tincture, . . . S94 tincture etherial, . 952 vinegar, . . . "52 ointment, . . . 992 Cantharis vesicatoria fluid extract, . 461 Caoutchouc, . . . 72: Caproyl 85 Ca P r yi 85 Capsella, fl. extract, 461 Capsicum elixir, . . 311 fluid extract, . . 460 myrrh tincture, . 951 oil, . . . . 640, 652 ointment, . . . 992 oleoresin, . . . 661 plaster 3S4 tincture, . . . S94 Capuchin plaster, . 393 Caramel 245 solution, . . . 245 Caraway essence, . 411 oil 647 seed, fl. extract, . 468 syrup S52 syrup, . . . 823 water 166 Carbazotate of am- monium, . . 149 Carbazotic acid, . . 57 Carbo animalis, . . 211 animalis, purine's, 211 ligni, . . ... 212 Carbolate of Iodine glycerite, . . 520 iodine, inhalent, . 10S6 sodium, . . . 757 Carbolated cam'r ice, 1146 with glycerin, 1149 glycerin jelly, . .1147 glycerin honey, . 11 47 tooth wash, . .1137 Carbolic acid, 56, 59, 672 acid glycerite, . . 517 acid liquefied, 56, 59 acid ointment, . 969 acid solution, . . 569 acid suppositories, 7S9 1213 Carbolic acid vapor 969 Carlsbad, salts, artifi- Castor beans, tincture, 048 acid water. . 165 cial 1116 leaves, fluid ext., 476 alkali Grantville, • 5S7 water solution, S6S oil emulsion, . 397 ointment, . 969, 1103 Carminative, black- oil, tasteless. . - salve, . . 970, 1 103 berry, . . * 1045 Castoria 1050 soap, . . . ■ 743 cordial. 1046 Castorol 1050 tooth-ache cure, 1120 Dewee's, 625 Castor, tincture, - tooth powder, . • 1139 elixir, Dalby's, . 3S0 tincture, etherial, . 952 Carbolized cosmol'e , 969 ginger, . .' . . 1046 Catalpa, lluid extract , 468 vaseline, . . • 969 mixture, Paris, . Cataplasm, emollient 75* Carbon, 210 Carminatives, 1045 Cataria, fluid extract 473 bisulphide, . . 212 Carmine S76 Catarrh, cream balm 1048 chlorides, . . . 213 coloring (red), . 246 cream salve, . 1047 dioxide, . . . 213 ink, . . 246, S76, 1173 cure 1048 hydrides, . 213 solution, 246 snuff 104S oil, . . . 654, 671 Carnauba, n. ext., . 46S remedy, i"47 oxides, . . . 213 wax 216 Catawba syrup, . paper, . . . 230 Caroba, fluid extract, 475 in 727 Carbonates, . 214 Carophvlles, fl. ext. 461 Catechol 727 Carbonate of ammo oil, '..... 647 Catechu, . . . 727. B77 nium, • M5 tincture, . . . 947 fluid extract, . . 495 barium, . 1S7 thina balsam, . 1S2 infusion, 537 bismuth, . . 192 Carpenter's square, liquid extract, . . 405 cadmium, . 203 fluid extract, 47" ointment, . 992 calcium, precipit't , 205 Carrageen syrup, S22 powder, comp'd, . 715 calcium, prepared 206 compound syrup, . 826 tannic acid, . . 727 copper, . . . 266 Carrot oil, ... 652 tincture, 897 iron, . . . 5ii Carrota, or carrot link troches 961 iron saccharated, 500 extract, . . . 46S Cathartic cordial, 1050 lead, . . . 696 Carthamus, . . . elixir, . . 312 . 313 lead ointment, 9S5 tinctorius, . . S76 . 904 laxative elixir, 313 camphorated, 9S5 tinct. fluid extract, 473 liver pills, . . . 1051 lithium, . . . 594 Carum carvi, ll. ext., 46S lozenges, 1052 magnesium, . 599 1 'arvene Catmint, fl. extract, 473 magnesium, heav) . 599 Carvol, .... 647 oil 652 magnesium, light 600 Carya alba, fl. ext., 473 Catnep, fl. extract, . 473 manganese, 615 Casca, fluid extract. 465 < 'aulophyllin, . 732 mercury, . . 531 Cascara amarga, fluid ( 'aulophylluin. fl. ext. 468 nickel, . . . 634 extract, . 473 compound, fl. ext., 4 s - potassium , . . 704 cordial, . . 312, [050 tincture, 947 silver, 176 sagrada elixir, 312 tincture COmp'd, . 949 lium, . 749 sagrada extract, . 444 < laUStic balsam, . . 1034 sodium, dried, 750 sagrada fluid ext., t hurchill's iodine, 559 strontium, . . 774 473. 476 490 lunar 147 zinc, precipitated, 1015 aqueous, . . 490 soda 746 1, . 213 sagrada liquid ext., 490 toughened, . . 173 acid true, . 214 sagrada lluid ext., 490 ' ■ pep'r, il. ex. 41.0 anhydride, 213 ( lascarilla extract, . 444 Ceanothin, 733 Carboni bisulphid'm 212 lluid extract, . . 465 1 leanothuscomp. syr. ium, . 210 infusion, . . . 537 fluid extract, . . < larbonol, . . . 9 5, 620 oil 652 < ledar ess< ace, . 411 Carburet'd h. 2x3 tincture, oil ( 'arc la:' 1" ... 84 541 < ledarwood oil, . fluid extract, . l"i mucilage, . . . ( 'e.lrat oil, . . . ll. extract comp., 482 . . ;>■ 1 ledron seed, fl. ext., 469 oil, . . . for perfumes, t lelastrus scandens, fl, tincture, 895 lluid extra, t, . . extract, . . . compound tincture , 896 oil '•1: 1 1 100 syrup, . . . 823 Castanea, fluid ext., 477 ■ ordial, . 1 100 Carduus, benedictus '. Iiite, . 740 compound, . . Moo fluid extract, , oil, elixir, compound, ;i | tincture, 947 bean, fluid 1 1' -' 11 e, ... 11 1 1214 Celery fluid extract, 461 Ceratum cetacei, 220 salt Il88 extracti cantharidis 220 oil 652 plumbi subacetatis, 221 guarana elixir, 333 resince 221 Celluloid, .... 722 resinre composftum 222 Cement 5U sabinae, .... 222 amber 1164 saponis, 222 aquarium, . 1 164 Cercis Canadensis, chrome, 1163 fluid extract, 473 diamond, . 1163 Ceresin 216 glass and metal, . 1 164 Cereus, fl. ex., . 461 ,4S7 glutina 1163 night blooming, for lamps, . 1 1 64 tincture, . . . 949 metal, .... 1 164 Cerevisiae fermen- rubber 1 164 tum 498 for rubber tire, . 1164 Cerii oxalas, . 226 tooth 11S8 Cerium, .... 225 transparent, 1 164 chloride, 226 Celandine, fl.ext., 468, 4S7 nitrate 226 Centaury, Am. fl. ext . 476 oxalate, .... 226 European, fl. ext., 474 oxides 226 Cephalanthus, fl. ext. 473 sulphate, . . . 226 Cera alba, 215 Cerolein, .... 214 flava 214 Cetaceum, 226 Cera.- 214 Cetin, 227 Cerasalbe, 974 Cetraria, fluid extract 473 Cerasein 732 decoction, . 268 Cerata, .... 217 Cevadilla, fluid ext., 462 Cerat de galien, . 224 Chalk cerate, . 225 Cerate 21S mixture, 622 acetate of lead, . 223 mixture, Richard's, 628 arsenical, . 225 ointment, . . . 992 blistering, . . . 219 powder, aromatic, 715 cacao 225 powder, comp'd, . 715 calamine, . . . 223 precipitated, . 205 camphor, . 218 prepared, . 206 cantharides, 219 troches, .... 962 chalk, .... 225 Chalybeate plaster, . 385 copaiba, 225 Chamomile, German, cosmetic, . 224 fluid extract, 469 ext. of cantharides 220 infusion, 536 Galen's, . . . 224 oil, 646 Goulard's, . 221 ointment, . 992 Kirkland's, 224 Roman, fl. ext., . 473 Marshall's, . . . 225 syrup, .... 823 neutral, Kirkland's , 224 tincture, . . . 946 pitch 225 Champagne, . n36 resin, .... 221 syrup, .... S53 resin compound, . 222 Chapman's copaiba rose, 225 mixture, . 629 savin, .... 222 Charcoal, .... 212 simple, .... 21S animal, .... 211 soap, .... 222 animal, purified, . 211 spermaceti, 220 ointment, . 992 subacetate of lead, 221 tooth paste, 113S Turner s, . . . 223 wood, .... 212 verdigris, . 225 Charts 227 Cerates, .... 217 Charta cantharides, 227 Ceratic acid, . 214 epispastica, 22S Ceratum, .... 21S potassii nitratis, . 228 camphora\ . 21S sinapis 229 cantharidis, • 210 Chaulmoogra oil, 642 Cheken or Chequin, fluid extract, . 469 Chelidonium majus, fluid extract, 468, 487 ! Chelone, glabra, fl. extract, . . . 473 : Chelonin, . . . 732 Chemic blue, . . . 877 Chemical action, . 19 affinity, ... 19 attraction, ... 19 food, .... S45 products, pharm'l, 23 products inorganic, 19 Chemicals, . . . 232 Chenopodium, fl ex. 461 oil, 647 Cherry birch, fl. ext. 473 essence, . . . 411 syrup, .... 798 laurel ointment, . 992 laurel oil, . . . 652 laurel water, . . 16S pectoral, . . . 1106 phosphate syrup, . S53 syrup, . .' . . 853 syrup, black, . . 850 syrup, red, . . 850 tooth paste, . . 1 138 tree gum, . . . 727 wild, fl. extract, . 478 Chestnut, horse, fl. ex. , 468 leaves, fl. extract, 477 Chewstick, fluid ext. , 474 Chewing gums, . . 730 Chian turpentine, . 663 Chickerberry oil, . 64 S Chicorium, fluid ext., 474 Chicory, fl. extract, 474 Chilblain ointment, . 1060 lotion 1060 Child's laxative, . . 1050 Chili saltpetre, . . 752 Chimiphila, fl. ext., 471 syrup, . . . . S24 Chimaphilin, . . . ,732 China clay, . . . 137 root, fluid extract, 474 Chinoidin, . . . in tincture, . . . S9S Chinoidine, . . . in Chinoidium, . . . 11 1 Chinoline, . . . 129 tartrate, . . . 130 Chiococca, fluid ext., 46S Chionanthin, . . . 732 Chionanthus, fluid ex- tract, . . . 474. 4S7 Chirata, fluid extract, 471 tincture, . . . 898 Chiretta, infusion, . 537 Chittem, fluid extract, 476 INDEX. 121 Chloral, ?6, 233 Chlorides, carbon, . 213 Chromic anhy- anhydrous, • 234 gold, . 1 So dride, ... 5 ", 230, bromide comp., . IIOO solution, . 1 129 Chromium, . . . 238 butyl, . . . . 201 tin • 773 compounds, . . 239 butyl, elixir, . • 3M uranium, . . • 994 oxides 239 S76 elixir, • 3M Chlorinated soap, ■ 743 Chromogene, . . hydrate, lime, . . . 209 Chrysarobin ointm't, Chrysophyl'm, fl. ex. 975 4' " hydrate elixir, . • 3i4 Chlorine, . ■ 235 hydrate butyl, . 201 acids, • 236 tincture, . . . 947 hydrate ointment 992 inhalation, . • 99 f > j Churchill's iodine syrup, . . . • 799 ointment, . . • 992 caustic, . • 559 Chloralum, . 140 solution, . . 235, 5^2 solution hypophos- Chlorate mercury, • 532 water, . . . 235, 552 phites comp'd, . 573 potassium, . • 704 Chlorodyne, . 895 , IIOI syrup hypophosph'i , S04 potassium elixir. • 314 Chlorodynia, . . . 1 102 Cicely, sweet, fl. ext. 475 potassium troches . 9 6 5 Chloroform, . 237 Cicuta, fl. ext., . 471 ■ 474 sodium, • 750 camphor emulsioi , 622 Cigarettes, asthmatic 1031 Chlorates, . . 2 55, 236 elixir, 315 Cigar flavoring, Ha- Chloric acid, . . . 236 liniment, . . 544 vanna, 4^5 ether, . . . i 0,766 mixture, 621 tree, fluid extract, 46S Chloride aluminium , 140 morphine tincture 899 Cimicifugafl. ext. ,460, 4S7 ammonium, 146 ointment, . 992 fl. ext. compound, 4S2 ammonium elixir, 3M spirit, . . . S O, 765 tincture, 899 ammonium syrup S43 tincture, . . S98 tincture, comp'd, 949 ammonium troche s, 961 water, . 166 Cimicifugin, . 732 43S amyl, . . . 151 Chloroformum, . 237 Cinchona bitters, arsenic, . . . 179 ; Chlorophyll, . . 24 s decoction, . 270 barium, . 188 Chlorous acid, 236 elixir, . . . 297 extract , 29S 444 bismuth, basic, 196 Chocolata, . . 237 bromine, . . 2c 1, 236 Chocolate essence, 417 extract, alcoholic, 444 cadmium, . . 203 extract, . 417 extract, aqueous, . 444 calcium, 206 fluid extract, . 476 extract, liquid, 477 cerium, . 226 syrup, . S53 fluid extract, . . 477 cobalt, . '. . 240 syrup, hot, 867 aromatic, . . 4S2 copper, . . . 266 Cholagogue, . 1025 compound, 4^2 gold and sodium, 179 Cholera cure, 1053 detannated, 47" gold ointment, 992 cures, . . . 1053 infusion, . . . 535 iron, . . . 500 drops, Russian, 1054 infusion acid, . . 537 iron and arsenic eli x. 315 drops, Thiele- iron and strychnine iron elixir, tasteles ?■ 314 mann's, . I055 wine 1009 iron tincture, . 907 mixture, larks,,,,'. . 628 iron, wine, . . . 100S iron tinct., ethena , 9O8 mixture, X.Y. Sun ,1054 syrup lead, . . . 698 mixture, Spark- tincture, 900 lead ointment, 992 man's, 628 1055 tinct'e ammoniated 949 lime, 2o', mixture, Squibb's, tincture compound. OUI lithium, . 595 mixture. Sun, . . tooth powder, . . 1 139 magnesium, 602 remedy, . . 1053 wine, . . IOOO, 100S manganese, 615 Specific, Australia! Cinchonia, 1 12 mercury, corrosive . 526 tincture, Asiatic, sulphate. . . . 112 mercury, mild, 525 Chromate barium, . Cinchonicine, in nickel, . . . . »34 bismuth, "'7 ( linchonidia elixir, . 315 phosphorus, '■7 1 lead 698 sulphate, 1 1 1 platinum, . mercury, . . . 532 < linchonidinse sulphas 1 1 1 potassium, . . . 711 potassium, . . . 711' Cinchonidine, . . 1 1 1 propylamine elixir 359 potassium, red. 702 elixir 315 silver silver 1-'. iron elixir, . 316 sodium 7-"" Chrome cement, . . [163 iron and arsenic elix. sulphur, 781 orange iron and strych, elix. tin solution, 592 red sulphate, . . . 1 1 1 zinc 1017 yellow Cinchonina, . 1 1 2 zinc, etherate, 81 Chromic acid, . 5 7. 239 < linchonime sulphas, 1 [2 Chlorides, ,23 acid solution, . nine, . . . I 12 1210 INDEX. Cinchonine sulphate, 112 Citro-tartrate sodium Cochineal fruit, red, 247 Cincho-quinine, . 129 effervescing, ' 751 mordant, . 7 . 774 elixir, .... 317 Citrus bergamia, 646 red 246 Cinnabar, .... 531 Civet ex. for perfumes ,H53 tincture, . . 903 .947 Cinnamic acid, . 647 Claret syrup, . S54 tincture, ammon'd, 950 aldehyd, 647 Claude's elixir, . 380 Cochlearia armoracia 465 Cinnamomum cam- Clay China, . 137 (scurvy grass) fluid phora, .... 727 Cleaning cream, 1 169 extract, . . . 474 Cinnamon ess., .411 , 766 Cleaver's fluid extract - 474 Cockleburr, fl. ext. . 469 fluid extract, . 461 Clifford's shampoo Cockroaches, tincture 950 oik 647 compound, . . 1 144 Cocktail shakes, . 866 powder compound, 714 Clothes cleaning com Cocoa, 237 spirit, .... 766 pound, . "1169 Cocoa cream, . . "43 syrup, . . . 798, 854 Cloth and glove Cocoaine or cocoa- tincture, 902 cleaner, . 1 169 cream, .... ii43 water, .... 166 Cloth cleaning com- Cocoanut oil, . 63S 642 Cinquefoil, fl. ext., . 469 pounds, . . . 1168 oil soap, 742 Cissampeline, 107 Clove anodyne tooth- Codamine, 666 Citrate ammonium, . M9 ache cure, . 1120 Codeia 114 Citrate bismuth, . 193 Clove essence, 411 Codeina, .... 114 bismuth and ammo- ess. for perfumes, 1152 Codeinje sulphas, 114 nium, 194 oil 647 Codeine, . . 114 666 bismuth soluble, . 194 ..Clover, sweet, fl. ext. , 475 sulphate, . . . 114 caffeine, no tops, red, fluid ext ,476 Cod liver oil, . 638 caffeine elixir, . 317 Cloves, fluid extract, 46 r with chem. food, 402 ,405 copper, .... 266 infusion, 537 emulsion, . 397 iron, .... 501 syrup 823 ferrated, . 400 iron and ammonium , 502 tincture, . . . 947 with hypophosp's 399 iron elixir, . 317 Coal oil, .... 654 with iodid potas. 400 iron syrup, 833 tar 694 iodo-ferrated, . 400 iron and quinine, 502 Coating, gelatin, 514 with iron. . . 400 iron and quin. elix. 317 sugar, .... 680 with lactophos. iron and quin. syrup ,834 Cobalt 240 iron, . 401 iron, quinine and chloride, 240 with lactophos. strychnine, . . 503 oxide 240 comp. . 401 iron, quinine and salts, .... 240 with lactophos. strychnine elixir, 3i8 Cobaltum, ... 240 lime, . 401 iron and strychnine Cobbler shakes, . . 865 with pancreatine, 403 syrup, 834 Coca elixir, 324 with pancreatine iron, quinine and fluid extract, . . 471 and pepsin, .. 404 strychnine elixir, 3i8 nucifera, 638 with pepsin, 402 iron, quinine and syrup 825 with pepsin and strychnine syrup, 834 wine, .... 1009 quinine 4C>3 iron and strychnine 503 Cocaina, .... 112 peptonized, . . 403 iron and strychnine Cocainae hydrochlo's, 113 with phosphate elixir, 3i8 Cocaine, .... 112 of lime, . . 402 iron wine, . 1002 discs, .... 542 with phosphate lithium, 594 elixir, .... 319 of lime and lithium effervescing 596 hydrochlorate, 113 wild cherry, . 402 lithium elixir, . 318 hydrochlorate elix. 319 with phosphates magnesium, 602 liniment, . . . 1093 compound, . 402 magnes. , granular, 600 oleate, .... 657 phosphorated, . 406 magnesium solution 869 toothache cure, 1121 stronger, 398 manganese, 615 Cocash, fl. extract, . 473 with wild cherry, 404 potassium, . 705 Cocculus Indicus, fl. with yolk of egg, 404 potassium mixture, 626 extract, . 461 tasteless, 397 sodium, .... 757 ointment, . . . 992 with extract of malt, 406 Citric acid, 57 tincture, 946 with glyconin. 404 acid solution, . 572 Coccus cacti, . 876 with iodine, . . 399 acid syrup, 793 lacca, .... 725 iodo-ferrated, . 1126 Citrine ointment, 9S0 Cochineal, 876 iodized, . . 399, 1126 Citronella oil, 652 compound, . 592 with lime, . . . 398 INDEX. 1217 Cod liver oil and milk . Collodium stypticum , 243 Compressed triturates, 872 peptonized, . 403 vesicans, 242 troches, . 872 mixture with hypo Colocynth apple, fl. ex. 474 Comptonia fluid ext. 474 phosphites, . 405 extract, . . . 445 Concentrated ext s. . 416 mixture with phos ■ extract, compounc , 445 essences, • 409 phates, . 405 fl. ext. compound 482 extract vanilla, . 420 ointment, . 992 oil, .... 640 solution phosphates phosphorized, . 1126 ointment, . 992 compound, • 576 soap, . . . 743 tincture, 9°3 Concentrations, ■ 731 Coffee elixir, . 319 Colocynthin, . 732 general formula for 731 essence, . . 417 Cologne, farina, . "57 Conderango, fl. ext., 474 extract, . . . 417 floral, . . . "57 Condensed milk, ■ 541 fluid extract, . 41 7,473 German, "57 Condition powders, . 1055 syrup, ... 41 7. S54 Hoyt's German, "53 powders, 1056 to 1058 syrup, hot, 867 lavender, . 115S Condy's fl. or solu'n, 586 Cognac essence, . 412 musk, . 1158 Cones menthol, . 649 oil 652 ♦ spirit, 88 Confectio laxativ e, . 1052 syrup, . . . 354 spirit, French, 88 Damocratus, • 875 Cohosh, black, fluic I water, . . . 770 opii, . . . 256 extract, . . 46 0, 487 white rose. . 115S piperis, . . • 257 black, fl. ex. comp , 482 Colognes and Toile t rosae, • 257 black tincture, 899 waters, . 1156 tosx canina?, • 257 black tinct. comp . 949 Colophony, . . 6c 2, 722 rosae gallicae, • 257 blue fluid extract 468 Color butter, . 249 , ngcT" scammonii, . 258 blue fl. ext. comp 482 Colored fires, . . 252 senna, . . 258 blue tincture, . 947 Colores, 244 sulphuris, . • 259 blue tinct. comp 949 Coloring burnt sugar , 245 terebinthenre, • 259 red ( baneberry ) carmine, 246 Confections, . 255, 260 fluid extract, 461 fustic yellow, . 248 Confection of almonds, 260 white fluid extract 461 grass-green, 248 aromatic, . . 260 Cola, fluid extract, 469 hair, . . . 107c , 1081 cherry laurel 1\ s. . 256 Colchicina, . . 114 hair oil, . "4i hips, . . • 257 Colchicine, . . 114 lemon-yellow, . 248 lemon, . . . 260 Colchicum extract, 445 liquids, . . . 245 opium, . . 258 extract acetic, . 445 liquids brown, 245 orange peel, . 260 fluid extract, . 466 orange, . 249 pepper, . • 257 root wine, . . 1000 recipes, . . 877 to 880 rose, . . ■ 257 seed wine, . . 1001 Colorless tine, iodine , 52i scammony, . 25S syrup, . . . 823 Colors, .... 244 scurvy grass, . 256 tincture, . . 903 powders, etc., . 250 senna, . . 258 tincture compounc I, 95'J show bottle, 250 sulphur, • 259 vinegar, . . 52 Coltsfoot essence, 435 turpentine, • 259 Colcothar, . . tin id extract, . 476 Congress water, so- Cold cream, . . 25 syrup, . . . 823 lution, . 868 Colinsonia, fl. ext., 437 Columbo, Am. fl. ext • 474 Conhydrine, . • "5. Collinsonin, . . 732 elixir, 3'9 Conia, . • "5 Collodia, . 240 fluid extract, . 47i Coniine, . . • "5 Collodion, . . 24 1,722 and rhubarb elixir 365 Conina, • 11; blistering, . . 242 Comfrev, tl. extract 47'' Conine, ■ US cantharidal, 241 syrup, . . . ,s2 4 hydrochlorate, • "5 with cantharides, 241 wine compound, 1014 inhalation, • 99 f » flexible, 243 Complexion powder "35 Conium abstract 47 iodinal, . 243 cosmetics, . 1132 ext. alcoholic, • 445 iodoform, . 244 < imposition powder . 720 fruit, fluid ext , • 471 Liebig's corn, . 244 Compound elixi r and iron elixir 320 styptic, . 243 phosphates, 356 s, fluid ex t-. • 474 styptic antiseptic, 243 < ^impressed bypode leaves, tincture :. • 946 Collodions, 240 mic tablets, . 872 oil, . . . 640 Colloid styptic, . 24 3, 244 lozenges, 872 ointment, . 992 Collodium, . . 241 powders, . . 872 syrup, . . . 825 cum cantharide, 241 pills, . . . 872 tincture, 0-1 flexile, . . . 243 tablets, . . . -;j 1 onservedecoch earie, 256 1218 INDEX. Conserves, . 255, 260 Cordial cascara, 312 , 1050 Cosmoline carbolized 969 Conserves de laurier celery, . . . 1 100 Cotarine, .... 666 cerise, . . . 256 cough, . . . 1062 Coto, fluid extract, . 465 Consumption cure, curacoa, 262 oil 652 1062, 1063 1064 diuretic, 1088 tincture, . . . 948 Contrayerva, tinct. 948 elixir, ferriphos Cotton, absorbent, . "94 extract liquid, ■\1') a, sordial, 262 fluid extract, . elixir 262 fluid (.■St. comp. !-< essence, . . 412 juice, 77'' Dandelion and rhub- arb, fl. ext. . 482 and sarsap. fl. ext. and senna fl. ext. 4S3 syrup, .... S25 Darby's prophylactic fluid, . . . 5S7 Daturia 115 Datura stramonium, fluid extract, . 4S7 syrup 82 5 Daturina, . . . 115 Daturine 11; sulphate, . . . 115 Decocta 267 Decoction, . . 33, 267 aloes, compound, cetraria, . . . 26S cinchona, . . . 270 pomegranate bark, 270 sarsaparilla comp. 269 Decoctions, . . . 269 other, .... 270 by water-bath per- colation, . . 26S Decoctum aloes com- positum, . . 269 cetrariaj, . . . 268 cinchona', . . . 270 granati radicis, . 270 sarsaparilla.* com- positum, . 269 Delphina, fluid ext. 46] Delphinum, tincture, 946 I >emar resin, . . . 723 Denarcotised opium, 663 Dentifrices . . .1136 Deodorized tincture opium, . . . 929 Depilatory liquid, . 1141 paste 114.. powder, . . .1141 Depilatories, ... 1 140 I lesiaurier's elixir. . Destillat.e, . . I distillates, . . . I >etannating elixirs, 2 B( 1 1 »euteropine, I teutoxide of nitrogen, 635 1 lewee's carminativ* . tincture guaiac, . 912 DeWessely's disin- fecting solution, 587 : 1 . . . [52,27] mucilage, . 271, 1166 syrup, . . Dextrinum, . . . --71 '"'■. • • 735 1 ii tro-quinine, . 1 -.'•) 1 lextrose, . . =1 I liachylon ointment, ■.:'■ plaster, .... 1220 I >ialysatx\ 272 Disinfectant solution Duboisia fl. extract, 468 Dialysate of aconite 273 Le Doyen's, 537 Duboisine, 115 belladonna, 273 Disinfecting fluid, sulphate, 116 Dialysates, . . 272 Mattenheimer's, 537 Duffy's elixir, 33i Dialysed iron, . 272 solutions, . . . 586 Dugong oil, . . . 642 iron elixir, . 323 solu., DeWessely's 587 Dulcamara, fl. ext. iron in scales, 272 solution, Farwell's 587 .... 47] . 474 iron solution, . 554 solution, Monsell's, 537 syrup 823 iron syrup, 840 solution, Seeley's, 537 Dulcietose, . 51; . 735 Dialysis, . . . 24 Disulphide of carbon 212 Dulcit, . . . ." 735 Diamides, . . 142 Distillation, . . . 26 Dutch liquid, . 80, 8< Diamines, 143 Distilled ext. buchu, 452 metal, .... 264 Diamond, . 210 ext. wild cherry, 452 Dwarf elder, fl. ext. 473 Diamond cement, 1 163 ext. witch hazel, . 452 Dye, hair, black, Diapente powder, 721 extracts, . . . 451 .... 1079, 1080 Diarrhcea mixture, 951 water, .... 167 hair, brown, 1080 mixture, Gould's, 629 Dita bark, fl. ext. . 461 hair, lightning, mixture, Squibb's 629 Dittany, Am., fl. ext. 474 .... 1079, 1080 mixt., Velpeau's, 629 Dobell's solution, . 587 lac, S77 remedies, . 1068 Dock, yellow, fl. ext. 472 Dyeing extracts, 877 tablets, . . . 1070 Dogwood, fluid ext. 47i Dyes, aniline, . . 154 Diastase, . 87, 27 2, 604 Jamaica, fl. ext. . 469 Dyes, 875 Diborocitrate lithiur n, 595 swamp, fluid ext. 474 hair, . . 1079, 1141 Dichloride chromiun 1. 239 Don't care syrup, S55 Dynamite, 5i6 Digestive dyspepsk i Donovan's elixir, 285 1 )ysentery remedies, 1068 remedy, . 1072 solution, 55° Dyspepsia cures, 1070 Digitalin, . 732 Dorema Ammoniacun ,728 lozenges, . . . 1072 Digitalis, abstract, 47 Double refined rock remedy, 1071 elixir, 323 candy syrup, . . 84S tonic, .... 1071 extract, . . . 446 Dover's elixir, . . 337 tablets, .... 1072 fluid extract, . 467 liquid, .... 950 fluid ext., acetic. 4S8 powder, . . 717 fl. ext., etherial, 493 syrup, .... 828 E infusion, . 53 5, 537 tincture, 917 oil, .... 640 Dracontium, fl. ext. 468 Earth's alkaline, . . 98 syrup, . . . 824 tincture, 947 Earth wax, 216 tincture, 905 Dragon's blood, 725 Easton's syrup, . 802 vinegar, 53 Draught, black, 536 627 Eau 453 Dill essence, . . 412 black, British, 627 Angelique, . . "37 fluid extract, . 46S . Vienna, . . . 536 de botot, . . . 1 140 oil, .... 641 Dr. De la Motte's de Cologne, . . 1162 water, . . . 164 golden drops, . 33i de javelle, 567 to 588 Dinitro-cellulin, . 722 Driers, pill, . 67S de lavande, 1162 Dioscorin, 732 Drop, black, British, 54 de luce, 948 Dioscorea, fl. ext. 461 Drops, Bateman's pec de violette, . . 1162 Diospyros, fl. ext. 474 toral 1 106 Eaux, 161 Dioxide of carbon, 213 cholera, . . . 1055 Eclectic extracts, 73i manganese, 614 cough, .... 1067 Eclectic powders, . 731 Dipterix, fl. ext. 461 Hamburger, . 1126 Economy in perco- Dipterocarpus turbi hop, . " . . ' . 95i lating, . . . 39 natus, . . Hunn's life, . . 1127 Ecuelle, the . 644 Dippell's acid elix. 380 Russian cholera, . 1054 Effervescing, citrate animal oil, . 641 Thielmann's chol- of lithium, . 596 Dirca palustris, fluic 1 era, .... 1055 citro-tartrate of extract, . • 474 Drosera,fl. ext. . 461 sodium, . . . 75i Discovery, medical, 1112 Drugs, animal, . . 23 powders, . 71310714 Discs, .... 542 difficult to percolate , 38 powders, aperient, 715 atropine, . . 542 mineral, 17 solution of lithia. 560 cocaine, 542 vegetable, . 19 solution of potash, 565 physostigmine, . 542 Drymy's winteria, fl. Egg albumen, . . 83 Disinfectant solutioi 1, extract, . . . 461 food, .... 1058 Girondin, . 537 Duboisia, .... "5 nogg, .... 627 INDEX. 1221 Egg nogg, syrup, . 856 Elixir arsenic and Elixir calisaya, 297 298 ointment, . 993 iodide mercury, 285 with beef ext., . 307 phosphate, hot, . 867 arse'e and strych'e, 2S5 beef and iron, . 307 phosphate, shake, 866 asafetida, . . . 2S5 and bismuth, . 297 Egyptian ointment, 993 atropine, 2S6 bismuth and pep- Elceo, succhara, . . 735 aurantii, 347 sin, . . . 307 Elaterin 274 bark and iron, 302 bismuth and powd'r compound, 716 beef 2M strychnine, . 299 trituration, 957 beef and iron, 2S6 with citrate of iron ,300 Elaterium, 274 beef, iron and cin- citrate of iron Elder, dwarf, fl. ext., 473 chona, . . ■ . 2S7 and bismuth. 300 flowers, fl. extract, 476 belladonna, 287 citrate of iron, flower, ointment, 992 berberine, . 287 bismuth and flower, water, . . T 7 J berberine and iron, 2SS strychnine, . 301 oil, . . . 640 to 652 berberine, bismuth detannated, 297 ointment, green, . 992 and iron, 2SS ferrated, . . 300 Elecampane, ext., . 447 bichloride merc'y, 320 ferrated with bis- fluid extract, . . 469 bismuth, . . . muth, . 300 Electic, active prin- bismuth, berberine ferrated with bis- ciples, . . . 731 and iron, . . 23S muth and Electrified air, . . 667 bism.andcalisaya, 299 strychnine, . 301 Electric liniment, 1093 bismuth, calisaya ferrated with oil, 1096 and iron, 300 strychnine, . 301 Electron 724 bismuth, calisaya ferriphosphated, 302 Electuaire theriaque, 875 and strychnine, 299 ferriphosphated Elements, chemical, 18 bismuth and iron, 2S9 with pepsin, . 302 Element'y subst'nees IS bismuth, iron and ferriphosp. with Elemi, 663 strychnine, . 289 strychnine, . 303 oil 652 bismuth, pepsin ferriphosp. with ointment, . . . 976 and quinine, 364 pepsin and plaster, .... 393 bism. and strych. 2S9 strychnine, . 303 Elephantopus.tl. ext. 474 bismuth, strychn'e ferrophosphorat- Elephants' foot, fluid and quinine, 364 ed with strych. 300 extract, . . . 474 bisulphate quinine, 364 ferrophosphorat- Electuaries, . 25510260 bitter, . . . 290 380 ed with bismu. 3' >-l Elixiria, .... 2 74 blackberry, 290 ferrophosphora'd 304 Elixirs, . . 274, 1072 black cohosh, . . 290 with hypophos- Elixirs, acid, . . . 380 black cohosh, comp 291 phites comp. 30S Dippell's, . . . 380 bromide amnion. . 291 and iron, 302 Haller's, . . . 380 calcium, . 292 and iron, with Vomer's, 380 iron, .... 292 beef extract, 307 Elixir acetate of po- morphine, . 293 ami iron, with tassium, . 282 potassium. . bismuth, . . 300 aconite 282 potass, comp. . 294 iron, bismuth adjuvans, . . . 282 potassium and ami beef, 307 album, . . 274 , 3^-7 hydrate chloral 294 iron and bismu.. aloes, .... 380 quinine, . with bi 307 alterative, . 10S7 sodium, . 295 iron and bismu.. amarum, . . 290 . 380 iodide calcium with lactopep- ammon'm bromide. 29] compound, . 292 tine. anise 283 buchu 295 iron, bismu. and anodyne, . compound, . 2<,'> pepsin, . . antiasthm.r 380 juniper and ace- iron, bismu. and antiasthmai tate p strychnine, . 305 baaves, . . . 380 Pareira Brava, . iron, bismuth, antifebrin, . buckthorn. 325 strychnine and antigoutteuxde vil- butyl chloral, . . |1 t pepsin, . . 306 lette, .... 380 butyl chloral hy- and iron, with antipyrin, . . . 284 . . ' . 321 lactopeptine, 308 antiscrofuleox, 950 caffeine citrate, 317 iron and pepsin, 302 aromatic, . . 280 , 284 ( ah iuni bromide, 2.|2 iron, pepsin and arsenii ..... 285 calcium hypophos. 335 Btrychnine, . 303 1222 Elixir calisaya iron and strychnine, . 303 iron and strych. 303 iron and strych. 301 iron and strych., with extract of beef, . . . 308 iron and strych. , with lactopep- tine, . . . 309 with lactopept'e, 30S withlactopept'e, 308 with lactophos- phate of cal- cium, . . . 309 with lactophos- phates comp. 310 with lactophos- phate of lime, 309 and pepsin, . . 306 and phosphate of iron, . . 302 with phosphates compound, . 310 with protoxide of iron, . . 310 and pyrophos- phate of iron, 304 pyrophosphate of iron and bism., 304 pyrophosphate of iron, bismuth and strychn'e, 306 pyrophosphate of iron, bismuth and pepsin, . 306 pyrophosphate of iron, bismuth and strychni'e, with pepsin, . 306 pyrophosphate of iron and strych. 305 with tinct. chlor- ide of iron, . 311 camphor monobro- mated, . . . 311 capsicum, . . . 311 carminat'e, Dalby's, 380 cascara sagrada, . 312 cathartic, . 312, 313 cathartic or laxat'e, 313 celery compound, 313 celery and guara'na, 333 chloral, . . . . 314 chloral hydrate, . 314 chloral hydrate and potass, bromide, 294 chlorate of potass. 314 chloride of ammo- nium, . . . 314 chloride of iron and Elixir chloride of iron, tasteless, chloride of propy- amine, . chloroform, . . cincho-quinine, . cinchona, . 297, cinchona, ferrated, cinchona, ferrated with bismuth, . cinchona, ferrated with bismu. and strychnine, . cinchonidia, cinchonidine, . cinchonidine and iron cinchonidine, iron and arsenic, cinchonidine, iron and strychnine, cimicifuga, citrate caffeine, citrate iron, citrate iron and calisaya, . citrate iron and quinine, . citrate iron, qui- nine and strych- nine, .... citrate iron and strychnine, . citrate lithium, Claude's, . . coca, cocaine, coffee, . . . cohosh, black, cohosh, bl'k comp columbo, columbo and rhu barb, . columbo, rhubarb and iron, conium and iron, cordial, . . . corrosive s u b 1 i mate, corydalis, . corydalis, comp. croton-chloral hy drate, curacoa, cyanide potassium damiana, . damiana comp dandelion, . dandeli'ncomp. 32 de garus, . Deslaurier's, detannating, 3M 359 315 317 298 300 300 301 315 315 316 316 316 290 317 317 300 317 3iS 3i8 318 380 324 319 319 290 291 319 365 365 320 280 320 320 321 321 262 321 322 322 322 37i 38i 380 280 Elixir digitalis, . . 323 dialysed iron, . . 323 Dover's, . . . 337 Duffy's, . . . 381 ergot 324 erythroxylon, . . 324 e succo liquiritioe, 381 eucalyptus, . . 324 eucalyptus, comp. 325 euonymus, . . 325 ferrated cordial, . 304 ferridialysati, . . 323 ferriphosphated cordial, . . . 360 flavoring, . . . 275 flavoring, soluble, 277 frangula, . . . 325 from fluid extracts, 279 gentian, . . . 326 gentian and bis- muth, . . . 327 gentian and citrate of iron, . . . 327 gentian, chlo. iron with quinine, . 331 gentian, chlo. iron, quinine and strychnine, . . 331 gentian, ferrated, 327 gentian, ferrophos- phated with strychnine, . . 329 gentian, ferriphos- phorated, . . 329 gentian, ferrophos- phorated, . . 329 gentian, iron and bismuth, . . 328 gentian, iron, bis- muth and strych- nine 328 gentian, iron and strychnine, . . 328 gentian and phos- phate iron, . . 329 gentian, phosphate iron and strych. , 329 gentian and pyro- phosphate iron, 329 gentian and strych- nine 320 gentian, strychnine and bismuth, . 330 gentian, with tinc- ture chlo. iron, 330 with quinine, . 331 with quinine and strychnine. . 331 gentian and tinc- ture chlor. iron with lactopep- tine 332 INDEX. 1223 Elixir gelsemium, . 326 Elixir iron protox. and Elixir matico, comp., 345 ginger, .... 332 iodide calcium, . 359 May apple, . . 345 glycyrrhiza, 342 protoxide and io- mono- bromated glycyrrhiza, comp. 343 dide potass. . 360 camphor comp., 346 gold, .... 38J protox. and qui- morphine, . 340 golden seal, 334 nine, . 360 morphine bromide, 293 gout 3S0 protox. quinine muriate of ammo. 314 grindelia robusta, 332 and strych. . 360 muriate of iron, guarana, 332 pyrophos. and tasteless. 314 guarana and cel- quinine, . 362 musk root, . 371 ery 333 pyrophos. and musk root. comp. 371 health, .... 33i quin. (neutral) 361 nervine, 1099 helonias, comp. . 333 pyrophos. quin. nervine, sedative, IIOO henbane, 335 and arsenic, . 363 neutralizing, . 366 hops 333 pyrophos. quin. nux vomica, . . 346 humulus, 333 and strych. opium 347 hydrastis, . 334 (neutral) . 361 opium deodorized. 347 hydrastis and bis- pyrophos. , quin. opium and ipecac, 337 muth, . . . 335 and strych. 363 opium, McMunn's, 347 hydrastis, ferri- quin. and pepsin, 354 orange, .... 347 phosphated, 334 quin., pepsin and orange comp., 34S 38i hydrastis and iron, 334 strychnine, . 355 pancreatin, 343 hydrastis. iron and strych. and pep. 353 pancreatin and bismuth, . . 334 quin., strych. and pepsin. . . . 349 hydrastis, iron and phosphorous, 35S pancreatin, pepsin strychnine, . . 335 jaborandi, . 338 and bismuth, . 349 hydrate chloral and juniper berries, . 338 paraldeffyd, 349 bromide potas- juniper, buchu and paregoric, . . . 928 sium. 294 acetate potass. . 296 Pareira brava, 350 hydrochlorate co- kairine, .... 338 Pareira brava and caine, 319 lactate iron, 339 buchu, 296 hyoscyamus, . . 335 lactate iron and pectoral, 38r hypophosphite cal- pepsin, . 339 pepsin, . . 350 to 35 cium, 335 lactic acid and pep- pepsin and bis- hypophosphite iron 336 sin 353 muth. 35i hypophosph. comp. 336 lactopeptine, . . 339 pepsin, bismuth hypophos. sodium, 336 lactopeptine, bism. and iron, 352 ignatia 336 and strychnine, 340 pepsin, bismuth, iodide calcium, . 336 lactopep. and bism. 340 iron and strych. 352 iodide iron tasteless 337 lactophos. calcium, 340 pepsin, bismuth iodide potassium, 337 lactophos. calcium, and quinine, 364 iodides and bro- and iron, . . 340 pepsin, bismuth mides comp. 1088 lactophos. calcium and strychnine, 352 iodo bromide cal- with pepsin, 34i pepsin and iron, . 353 cium compound, 1088 lactophosph. lime, 340 pepsin, iron and iodo bromide cal- lactucarium, . 342 strychnine, . . 353 cium compound, 292 laxative, 34i pepsin and lactic ipecac 327 laxative or cathar- acid 353 ipecac and opium, 327 tic, . . 313, 1049 pepsin, other, . 355 iron and bismuth, 289 leptandra, . 342 pepsin and p 35S bromide, . . 2<;2 liquorice, . 342 pepsin and quinine 354 bism. and strych. 28(j liquorice comp. 343 pepsin, t c|uinin<- and calisaya, 302 long life, . . . 38l and iron. calisaya and bis. 300 adlongam vitam, . 884 pepsin, quinine, calisaya, bismuth lupulin, . . 343 iron ami stiyi Q. 355 and strych. . 301 magnesia and pepsin, quinine calis. and pepsin, 302 rhubarb, 366 .iml strychnine, 354 calis. and strych- malt 344 pepsin and strych. 355 nine, . . 301 , 303 malt and iron, 344 pepsin and wafer and pepsin, . 353 malt with bypoph's, 344 asli 355 phos., quinine mandrake. . J45 percolating men- and strychnine 357 mandrake, comp., 345 struum, . 277 1224 INDEX. Elixir Peruvian bark Elixir pyrophosphate Elixir tartar emetic, 372 with protoxide of of iron, quinine tonic, .... 38i iron 310 and strych. (neu- tonifebrifuge quin- phosphate of cal- tral) 361 quinia et caffe. . 380 cium, 356 quinine, 363 tonique, antiglair- phosphate of iron, 356 quinine, bismuth eux, .... 38r phosphate of iron and pepsin, 364 valerian, 372 and quinine, 356 361 quinine, bismuth valerianate ammo- phosphate of iron, and strychnine, 364 nium, 373 quin. and strych- quinine bisulphate, 364 valerianate amm. nine . . 359 361 quinine bromide, . 295 with chl. hyd. 373 phosphate of lime, 356 quinine and pepsin, 354 valerianate amm. quinine, . 364 quinine, pepsin and and iron, . . 374 quinine and iron, 356 iron, .... 354 valerianate amm. phosphates comp., 356 quinine, pepsin, and morphine, . 374 phosphoric acid, . 357 iron and strych. 355 valerianate amm. phosphorus 358 quinine, pepsin and quinine, 374 compound, . 353 and strychnine, 354 valerianate amm. and nux vomica, 358 quinine phosphate, 364 and strychnine, 375 iron, quinine and red 307 valerianate iron, . 375 strychnine, .. 358 rheumatic, . . . 1 109 valerianate mor- pilocarpus, . 338 rhubarb, . . . 365 phine, 375 pink root compound 359 rhub. and columbo 365 valerianate q u i - podophyllum, . . 345 rhubarb, columbo nine 375 compound, . . 345 and iron, 365 valerianate strych. 376 potassium bromide, 293 rhubarb and potas- valerianate zinc, . 376 bromide comp., 294 sium, 366 veratrum viride, . 376 bromide and chlo- rhubarb and mag- vicerale, Hoffman- ral hydrate, . 294 nesia, 366 ni, . . 348 38i cyanide, . 321 roborans, . 381 902 viceral, Boer- proprietatis, 884 rubrum, . 274 367 haave's, . 380 propylamine, . 359 salicylate propyla- vitriol, .... 73 propylamine sali- mine, 367 wahoo, .... 325 clyate, 367 salicylate sodium, 367 wild cherry, 376 protoxide of iron, 359 salicin, .... 367 wild cherry, comp. 373 protoxide of iron salicylic acid, . . 368 wild cherry, detan- and iodide of salutis, . . 381 939 nated, . . . 376 calcium, . 359 santonin, . . . 368 wild cherry, fer- protoxide of iron sarsaparilla, comp. 368 rated, 377 and iodide of scilla, compound, 3§9 wild cherry, ferro- potassium, . 360 sedative, 294 phosphated, 378 protoxide of iron senna, .... 369 wild cherry, ferri- and quinine, 360 senna, compound, 369 phosphated, 377 protoxide of iron, simple 2S0 yellow jasmine, . 326 quinine and sodium bromide, . 295 yerba santa, . . 373 strychnine, . 360 squill, compound, 369 yerba santa, comp. 379 pyrophosphate of stillingia, . 37o Elixirs requiring per- iron 360 stillingia, comp. . 37o colation, 278 pyrophosphate of Stoughton's, . 381 with salts in solu- iron and cincho- strychnine, 370 tion 279 nidine, . 362 strychnine and bis- Elm mucilage, . . 633 pyrophosphate of muth, . . . 2S9 slippery, fluid ext. 476 iron and quinine, 262 strychnine and pep- Embalming fluids, . 569 pyrophosphate of sin, .... 355 Emetia 116 iron, quinine and sumbul, . . . 37i Emetic, acetous, 949 arsenic, . . . 363 sumbul, comp. 371 tartar 156 pyrophosphate of svapnia, 37i Emetina, .... 116 iron and quinine taraxacum, . . 322 Emetina ointment, 992 (neutral), 361 taraxacum, com- Emetine, .... 116 pyrophosphate of pound, . 322 371 Emetinia, .... 116 iron, quinine and tartrate antimony Emollient cataplasm, 75S strychnine, . 363 and potassium, 372 Emplastra, 382 1225 219, Emplastrum ammo- niaci, ammoniacium hy- drargyro, arnicse, asafsetidse, . belladonnae, califaciens, cantharidis, cantharidum, ordi narium, . . . cantharidum per- petuum, . capsici, cerussse, ferri, . . . • • fuscum camphor- atum, . . • galbani, . . • hydrargryri, . . ic'hthyocollse, . . lithargyri, . . . lithargyri comp. . opii picis, .... picis burgundicae, picis canadensis, . picis cum canthar. plumbi, plumbi iodidi, resinre, . saponis, saponis fuscum, . Emulsitication, . Emulsin, .... Emulsio olei morr- hux- fortior, Emulsion almonds, asafedita, . . . balsam fir, . . balsam Peru, . . Canada balsam, . castor oil, . cod liver oil, . , ferratcd , with iodide potassium, . iodo-ferrated, . with iron, . . with lacto-phos- phatescomp. with lacto-phos- phate of iron, with lacto-phos- pbate of lime, and malt ext., . with pancreatine with pancreatine and pepsin, . witli pepsin, with pepsin ami quinine, of 333 333 3S3 3S4 386 3S4 385 38S 3S4 ' 385 I 385 386 386 386 387 39° 390 387 388 388 388 389 389 390 390 391 39i 395 645 398 408 408 407 408 407 397 397 400 4> >u 400 400 401 401 406 403 4"4 I 1 '-' 403 Emulsion cod liver oil peptonized, . phosphorated, . with phosphates, with phos. lime, with phos. lime, and wild cherry, 402 stronger, . . 398 with wild cherry, 404 403 406 402 402 with yolk of egg, 404 copaiba, 406 hospital, . . . 405 olive oil, . . . 407 turpentine, 407 wax, .... 408 Emulsions, 394 Emulsiones, . . . 394 general directions for preparing, . 395 Enamel, liquid, . 1132 Enfleurage, . . 76, 645 Eosine 155 Ephedra, fl. extract, 465 Epigxarepens, fl. ex., 474 Epilobium, fl.ext.,474 ,4S7 Epsom salt, . 601 Epihegus, fl. extract, 474 Equisiticum, fl. ext., 46S Eradicator corn, 1059 Eraser, ink, . . . II 7 8 Erasing fluid, ink, . 1178 Erasive soap, 1 169 Eremocarpus, ll. ext. 465 Ergota, fl. extract, . 477 Ergot corn, fl. ext., 476 elixir 324 extract, 446 11. ext., acetic, 4S8 fl. extract, . . . 477 fl. ext., etherial, . 493 liquid extract, . 477 infusion, 537 oil 642 tincture, 906 tincture etherial, . 952 wine, .... IOOI Ergotin, . . . 44''. 7 J2 Bonjean's, . 446 Erigeron canadense, 647 fl. extract, . . . 461 oil, 647 tincture, . . 948 Eriodictyon, 11. ext. 161,487 Erweichende K tauter, 75S Eryngium aquaticum 11. extract, . 4 f 'S,4S7 yucca-folium, tl. ex. r < gO water, ll. extract, ... r Ervthr • acentaiinun tl. extract, . . . 171 4? 3 1155 409 43'' 4'4 4i" 410 Erythracea, fl. ext., 474 Erythromannit, . . 735 Erythroplceum, fl. ext. 465 Erythroxylin, . . 73 2 Erythroxyline, . . 112 Erythroxylon coca, fl. extract, . . 471 elixir, .... 324 syrup S25 wine 1009 Eserine 123 salicylate, . . . 123 Esprit de bouquet, . . Esprits Essence, absinthe, allspice, almond, almond, for per fumes, angelica anise, anisette, apricot, artificial, apple, artificial, . banana, artificial, bay, beef bergamot, . bergamot for per- fumes, . . . bitter almond, blackberry, artifi'l, bl'k currant, artifi. blueberry art ill. . bouquet, . . . bouquet sachet, . brand)' calamus, . . . caraway, . . cardamom, cassia for perfu's, cedar celery chocolate, . . . cherry cinnamon, . 41 clove 4 11 cloves for perfum'-, 1 1 52 410, 764 440 428 428 429 410 416 410 410 429 429 430 115? it- 4>" 411 4" 411 411 411 417 411 7'-' coffee coltsfoot, . . coriander, . cranberry, artific'l . . dill fennel i 1 -' gin 1 !■'' rry, artifi. 43" grape, artificial, , H" hemlock 11- 417 41- 135 li a 130 ti- ll- 12:26 INDEX. Essence Jamaica gin- Essence wild cherry Etherial tinct. castor, 952 ger, . 417, 41S, 1073 artificial, 434 tinct. chlorid. iron, 908 Jamaica rum, . 1189 wintergreen, 41 5, 707 tinct. ergot, . . 952 juniper. 412 wormwood, 416 tinct. iodine, . 952 kummel, 440 ylang ylang, . 1 164 tinct. iodoform, . 952 lavender, . 413 Essences, . . . 408 tinct. lobelia, 921 952 lavender, for per- artificial fruit. 427 tinct. nux vomica, 952 fumes, . . . 1152 cordial, 439 tinct. valerian, 942 lemon, . . 413 76S concentrated, . 409 Ethylamine, . 441 lemon for perfum's, "52 used for perfumes 1152 Ethyl 85 440 lemon grass, . 1152 proprietary, 1073 acetate, ... 78, 79 limes, .... 413 Essentia?, . . . 408 alcohol, . . 85, 86 mace, .... 413 Essential oils. 642 benzene, . . . 190 melon, artificial, . 430 oils, solutions, 409 benzoate, . 78 mustard, 413 Electrotype, moulds 191 bromide, . . 78, 79 nectar 431 Ethane, . . . 213 chloride, . . 78, 80 nectarine, artific'l, 430 Ether 77, 78 cinnamate, 182 neroli 1152 acetic, . . . 78, 79 ethers 78 nutmeg, . 413 , 77o benzoic, . . 7S formate, . . . 78 orange, 414 butyric, . . 78 hydrate, . . . S6 orange for perfum. 1152 chloric, . . .80, 766 iodide, .... 78 orgeat, .... 43i formic, . 78 nitrate, ... 78, 80 orris, .... 418 hydrobromic, . 78, 79 cenanthylate. . 78 parsley, 4M hydrochloric, . 78, 80 oxide 78 patchouly, . 1152 hydriodic, . 78 pelargonate, . 78 peach, artificial, . 432 nitrous, . 78, 80, 761 sebacate, . 78 pear, artificial, 432 nitrous, concen Ethylate of sodium, 757 pennyroyal, . . 414 trated, . . 80, 761 Ethylene bichloride, 80 peppermint, 414 . 769 nitrous, spirit, 760 Ethylic alcohol, . . 86 pimento, 414 cenanthic, . 78 Eucalyn, .... 735 pineapple, artific'l, 432 pelargonic, 78 Eucalyptol, . . . 648 plum, artificial, . 432 petroleum . 1 8 5, 671 Eucalyptus, . . . 324 prune, artificial . 433 purified, . . 79 balm 1032 quince, artificial, . 433 sebacic, . . 78 compound, elixir, 325 raspberry, artific'l, 433 spirit, . . . 759 fluid extract, . 460 red cherry, artifi'l, 434 spirit, compound 760 globulus, 648 red currant, artifi'l, 434 stronger, . . 79 oil 648 rose, .... 414 sulphuric, . 78 ointment, . 976 rose geranium, 1152 washed, 79 syrup 823 rose, triple. "52 Ethers, 77 tincture, . . . 948 rosemary, . 415 ethyl, . . . 78 Eugenol, . . 647, 649 rosemary, forperf. 1152 Etherates, 80 Eulachon oil, 642 rum Jamaica, . 1189 Etherate ammonia 81 Euonymin, 732 rum New England 1188 camphor, . 81 Euonymus, elixir, . 325 rum St. Croix, 11SS cantharides, . 81 extract, 446 sage 415 chloride zinc . 81 fluid extract, 469, 487 santal, for per- phosphorus. 82 syrup 825 fumes. "53 sulphur, 82 Eupatorin, . . . 732 sarsaparilla, 415 816 Etherial ext. meze Eupatorium aromat- sassafras, . . . 415 reon. . . . 44S icum, fl. ext., 471 .474 sherbet, . . . 41S fluid extracts, 492 perfoliatum, fl. ex- spearmint, . 415 769 fl. ext. cantharides , 493 tract, . . 471, 474 spruce 415 fl. ext. cubeb. . 493 purpureum, fl. ext. 474 strawberry, artifi- fl. ext. digitalis, 493 Euphorbia, corallata, cial, .... 434 fl. ext. ergot. . 493 fluid extract. 461 sweet flag, . 410 fl. ext. foxglove, 493 hipericifolia, fluid tonka 41S oil 82 extract, . 487 vanilla, .... 419 tinctures, . 952 ipecacuanha, fluid verbena, 1152 tinct. acetate iron 907 extract, . . . 465 whisky, bourbon, . 11S9 tinct. aconite. 883 pilulifera, fl. ext., 465 whisky, rye, . 1 190 tinct. asafetida, 952 Euphorbin, . 732 wine, .... 1186 tinct. cantharides 952 Euphorbium, 729 INDEX. T2-27 Euphorbium ointm't, 992 plaster 393 resinifera, . . . 729 tincture, . . . 946 Euphrasia, fluid ext. 474 Eupurpurin, . . . 732 Evaporation, . . 27 Evening primrose, fluid extract, 474, 487 Excelsior inhalant, mead, . . . mead, extract, mead, syrup. . Excipients, pill, Expectorant, Expressed juices, ex tracts from, Expression, . . Exsiccated alum, Exterminators and destroyers, Extracta, . . destillata, . fluida, ... Extract aconite lvs aconite root, . aloes, ... aloes, aqueous, alterative, . ambergris, for per- fumes, . . ambrette, for per fumes, . . apple, artificial, apples, ferrated, apricot, artificial arnica, flowers, arnica, root, . angelica. . . angelica, for per fumes, angostura bitters banana, artificial bark, beef, . . . beef tea. hot, . belladonna, alco holic. birch beer, bitters, aromatic blackberry, artifi black currant, art blessed thistle. blueberry, artific'l blue flag, . I'.oker's bitters, Bochu, distilled, buckbean, . . buckthorn, butternut bark, calabar bean, . io36 424 423 424 677 1066 442 29 138 44i 45i 453 443 443 443 443 1027 "53 "53 42S 446 428 443 443 416 "53 436 429 444 416 867 443 425 436 429 429 444 43" 447 437 542 450 449 447 449 Extract calumba, cascara sagrada, cascarilla, . cassie or acacia, chocolate, . cinchona. . . cinchona, alcoholic, 444 cinchona, aqueous, 444 civet, for perfumes, coffee colchicum, . colchicum, acetic, colocynth, . . . colocyth, comp. . columbo, . conium, alcoholic, couch grass, . . cranberry, artific'l, cubebs and copaiba Culver's root, dandelion, dandelion, liquid, digitalis, . . . elecampane, ergot euonymus, frangipanni, . frangula, . fustic 877 gelsemium, alcoh'ic, 446 444 444 "53 417 445 445 445 445 444 445 450 430 723 448 450 479 446 447 446 446 "55 449 calamus or blue Bag, 1 1 1 gentian, ginger ale, ginger, soluble, glycyrrhiza, pure, gooseberry, artiti Goulard's, . grape, artificial, henbane, . . hop, . . . huckleberry, artifi. 430 hyoscyamus, alco- holic, . . indigo, . . . inula, . . . iris, .... jaboramli, . jalap, Jamaica ginger, .... 417. 1073 Jamaica ginger, aromatic, Jamaica ruin, . jasmine, triple, jockey club, juglans . . . juniper berries, lemon, . lemon, soluble, leptandra, - , lettuce, . . lily of the valley, pure. 447 877 447 447 447 447 1074 ii-., [15] "55 447 775 41 ! 422 ip 1 r I'- ll' Extract liquorice, purified, . . . 776 liquors, . 1185101191 logwood, . 448, 877 malt, . . 44S, 604 malt, liquid. . . 605 malt combinations, 607, 611 malt with cod liver oil, .... 406 mandrake, . . . 449 mead excelsior, . 423 mead, soluble, . 423 meat 416 mezereum, . . . 44S mezereon etherial, 448 melon, artificial. . 430 musk root, for per- fumes, . . .1153 musk seed, for per- fumes, . . . 1 1 53 musk for perfumes, 11 53 musk 1 1 55 nectar, flavoring, 431 nectarine artificial, 431 night-blooming cereus, . . .1155 nux vomica, . . 44S opium 449 orange bitters^ . 437 orange flower, triple, . . .1152 orange soluble, . 424 orgeat, . . . . 431 orris 41 S orris for perfumes, 1153 Ottawa beer, . .425 Pareira, . . 44c) patchouly. . .1156 peach, artificial, . 432 pear, artificial, 432 Peruvian beer, 42s Peruvian bitters, . 438 physostigma, . . 449 pilocarpus, . . 447 pineapple, artific'l, 432 pinus Canadensis, 1 ■ • — 4 plasters, . . . 393 plum, artificial, . \ \2 podophyllum, . . 111 poppy Id prune, artificial, . 1 1 1 quassia, . . . \\ \ quince, artificial, raspberry, artificial, 1 ; \ red cherry, artifi- cial, . ' . . . i;i urrant, artific. 434 rhatany, . . . 44S rhubarb, . . . 450 rhubarb, comp. , . 450 triple, . 1 152 1228 INDEX. Extract root beer, . 427 Extracts soluble, gen- Extractum euonymi, 446 sarsaparilla comp. eral formula for, 421 eupatorii, fluidum, 471 concentrated, . mi triple, from po- felicis, liquidum, 462 sarsapar., stillingia mades, . "51 ferri pomatum, 446 and red clover. mi Extractum absinth- frangulas, fluidum, 477 sarsapar., soluble, 424 ium, .... 443 gelsemii, alcoholi- savine 45o aconiti, .... 443 cum, .... 446 Shaker's roots, 1074 aconiti fluidum, . 459 gelsemii, fluidum, 460 sherbet, . . . 418 aloes, .... 443 gentianas, . . . 446 spruce beer, . . 427 arnica? radicis, 443 gentianas, fluidum, 471 stephanotis, 1156 arnicas radicis geranii, fluidum, . 471 stramonium, . 450 fluidum, 47i glycyrrhizas, fluid'm ,471 strawberry, arti fie. 434 aromaticum fld'm, 459 glycyrrhizas, liqui'm ,491 stomach bitters, . 433 aurantii a m a r i glycyrrhizas, pura, 446 squill 450 fluidum, . . . 466 gossypii radicis, Stoughton bitters, 433 belladonna;, 444 fluidum, . 460 sumbul for per- belladonnas alco- graminis, . 450 fumes, "53 holicum. 443 grindelias, fluidum, 464 tolu soluble, . . 424 belladonna; fld'm 459 guaranas, fluidum, 464 tonka, .... 418 belae liquidum, 489 hasmatoxyli, . . 447 taraxacum. 450 brayera fluidum, 459 hamamelidis, dis- tuberose, triple, . 1152 buchu distillatum, 452 tillatum, 452 upper ten, . . . 1 1 56 buchu fluidum, 466 hamamelidis, fld'm 478 valerian, 450 calami 444 Helenii, 447 vanilla, . . .419 , 420 calami fluidum, . 459 hydrastis, fluidum, 464 vanilla, concent'd, 420 calumbas, . 444 hyoscyami, fluid'm, 467 vanilla, fortified, . 420 calumbas fluidum, 471 Indian cannabis, . 444 vanilla for perfu. 1154 cannabis Indicas, . 444 ipecacuanhas, flui- vanilla, tonka, 420 cannabis Indicas dum, .... 478 violet, .... violet, triple, . . 1156 fluidum, 459 iridis, .... 447 1152 capsici fluidum, . 460 iridis, fluidum, 464 wahoo, .... 446 cardui benedicti, . 444 jalapa, .... 447 white rose, . . . 1156 castaneaa fluidum, 477 jaborandi, . 447 wild cherry bitters, 439 cascara sagrada, . 444 juglandis, . . . 447 wild cherry, distill. 452 cascara sagrada kramerias, . 448 wild ginger for liquidium, . 490 kramerias, fluidum, 472 perfumes, . . "54 cascarillas, 444 lactucas, 448 wild olive, . . . "56 chimaphllas fld'm, 471 lactucarii, fluid'm, 478 wintergr. , soluble, 425 chiratas fluidum, 471 leptandras, . . . 44S witch hazel, distill. 452 cinchonas, . 444 leptandras, fluid'm, 472 wormwood, 443 cinchonas fluidum, 477 lobelias, fluidum, . 472 ylang ylang, . . "55 cinchonas liquid'm 477 lupuli, .... 443 Extracts, .... 441 cimicifugas fld'm, 460 lupulinas, fluidum, 460 bitters, .... 43b cimicifuga liqd'm 460 malti, .... 443 concentrated, . . 416 cocas liquidum, 47i matico, fluidum, . 467 distilled, . . . 45i colchici radicis, . 445 mezerii, .... 448 eclectic, 73i colchici radicis fid. 466 mezerii, fluidum, . 460 liquid, . . 453 , 493 colchici seminis fld. 466 nucis vomicas, 44S flavoring, . . . 40 S colocynthides, 445 nucis vomica, fluid- fluid, . . . . 453 colocynthides comp • 445 um 464 of flowers, . 645, 1151 conii alcoholicum, 445 opii, .... 449 from expressed conii fluidum, 471 opii, liquidum, 491 juices, . . . 442 cornus fluidum, . 460 papaveris, . 449 used for dyeing, . 377 cubebas fluidum . 460 Pareiras brava, 449 gen'l formula, for 442 cypripedii fld'm. . 460 Pareiras, fluidum, 472 handkerchiefs, "54 digitalis, . . . 446 Pareiras, liquidum, 472 other, .... 45i digitalis fluidum, 467 physostigmatis, . 449 for perfumes, . . 1151 dulcamara* fluid'm 47i pilocarpi, fluid'm, 472 powdered, . 441 ergotas, .... 446 podophylli, . . 449 proprietary, 1073 ergotas, fluidum, . 477 podophylli, fluid'm, 464 solid 441 ergotas, liquidum, 477 pruni Yirginianas, soluble, flavoring, 421 erythroxyli, fluidum .471 destillatum, 452 INDEX. 1229 Extractum pruni Vir False bittersweet, fl. Ferri sulphas exsic- ginianas, fluidum ,478 extract, , . . 473 catus, . . . 510 quassiae, 449 gromwell, fl. ext., 469 sulphas prcecipitat's ,510 quassia;, fluidum, 472 unicorn, fl. ext., . 462 valerianas, . 5" rhamni frangulce, 449 Farina cologne, . . "57 Ferric acetate, . . 5" rhamni frangula Farwell's disinfect- acetate solution, . 553 liquidum, 478 ing solution, 587 chloride, . . . 500 rhei, 450 Fatty oils, . 645 654 chloride solution, 554 rhei, compositum, 450 Favorite rheumatic citrate, .... 501 rhei, fluidum, . . 467 remedy, . . . 1 108 citrate solution, . 555 rhois glabra fluid., 472 Fayard papier, . 230 hydrate, 507 rosas fluidum, . 472 Fehling's solution, . 5S7 hypophosphite, 505 rubi fluidum, . 467 Fel bovis, . . . 497 nitrate solution, . 556 rumicis, fluidum, 472 bovis inspissatum, 497 oxide 512 sabinre, fluidum, . 460 bovis preparatus, 497 phosphate, . . . 508 sanguinariae, fluid. 460 bovis puriticatus, 497 pyrophosphate, . 509/ sarsae liquidum, . 478 Fellow's syrup hypo- salts 498 sarsaparilla;, fluid., 478 phosphites comp 837 sulphate, basic so- scillre 450 Female pills, . . . 1079 lution, . . . 557 scilla;, fluidum, . 460 remedies, . . . 1076 sulphate, normal Scutellaria?, fluid., 478 Fennel essence, . 412 solution, . . 55S senegae, fluidum, . 467 seed, fluid ext., . 469 valerianate, 5" sennas, fluidum, . 479 syrup, .... S23 Ferricyanide of po- serpentariro, fluid., 464 water, .... 167 tassium, . . . 7" spigelian, fluidum, 472 water, fluid ext., . 462 Ferriphosphat'd elix. stramonii, . . . 450 Fenugreek, mucilage 633 gentian, . 334 stramonii, fluidum, 467 Fermentum, . 498 Ferriphosphorated stillingix-, fluidum, 472 Fern, male, fl. ext., 461 elixir gentian . 329 taraxaci, 450 sweet, fluid ext., . 474 Ferri-phosphat'd elx. taraxaci, fluidum, 479 Ferrated elix. of gen- gent, and strych. 329 taraxaci, liquidum, 479 tian 327 elixir wild cherry. 377 trifolii tibrina, 450 elix. wild cherry, 377 Ferrocyanide of iron, 512 tritici 450 emulsion cod liver of potassium, . 706 uvx- ursi, fluidum, 472 oil 400 of zinc 1021 valerinre, 450 extract apples, 446 Ferrophosphated cor- valeriase, -fluidum, 467 ext. apples tinct., 908 dial elixir, . 360 veratri viridis, fluid. , 460 Ferri arsenias, . 499 elixir of gentian, . 329 viburni, fluidum, . 467 carbonas sacchara- elixir wild cherry, 378 xanthoxyii, fluid., 460 tus 500 Ferroso- ferric oxide, 5 1 2 zingiberis, fluidum, 460 chloridum, . . 500 Ferrous lactate, . 506 Extraits 645 citras 50I phosphate, 509 Eyebright, fl. ext., . 474 et ammonii citras, 502 oxalate, 507 Eye salve, astringent, 1076 et ammonii sul- oxide 512 salve, standard, . 1076 phas, . . . . 503 salts, .... 498 salves, . .1075, 1076 et ammonii tar- sulphate, water 1075 tras 503 sulphate, precipi- waters, .... 1075 et potassii tartras, 504 tated, . . . SI0 et quinina.' citras, 502 Ferrum et strychninae ci- dialysatum, . . F tras 503 Ferula galbaniflua, 729 hypophosphis. SOS oarthax, Face lotion, . 1148 iodidum sacchara- Fetid spirit oi ammo. powder, . . «35 tum 505 Fever, bush fl. ext., r •■ powder, bloom of lactas Feverfew, fl, ext. . . 47'' Ninon, . "35 oxalas oil powder, invisible, "35 oxidum hydratum, 5"7 t incline, . . . powder, pa : "35 oxidum hydratum Feverwort, fl. ext., . 17'' pow'r, swans down "35 cum ma 508 Fibrin "I and toilet pow- perchloridt, solu'n, 555 ifl soap, . 743 ders "35 phosphas, . lilix. mas, fl. ext., . r ■-■ Fagus ferruginea, fl. pyrophosphas, Filteration, extract, . . . 474 sulphas, . . . Filt'ring, economy in, 39 1230 INDEX. Filtering paper. . 232 Fluid, Darby's pro Fluid ext. anise, star 46S Filter rack, spiral, . 30 phylactic, 5S7 anisum. 468 Fine pomades, . "45 hydrastis, . 480 anthemis, . 473 Fineness of powder, 3i lightning, . 1096 apium 461 Fioravanti balsam, . 772 magnesia, . 560 apocynum, . . 468 spirit, .... 772 Mattenheimer's, 587 apple, bitter, . . 474 Fir, balsam, . 1S2 663 washing, 1169 apple tree bark, . 476 bals'm,bark,fl.ext. 473 white, Coutaret's, 587 aralia compound, 485 Fir-wood, oil, . . 650 Fluid ext. abies bal aralia hispida, 473 wool oil, 650 samea, . 473 aralia nudicaulus, 473 oil, inhalation, 996 abscess root, . 469 aralia racemosa, . 473 Fire, blue, 253 absinthium, 473 aralia spinosa, 473 green, .... 253 acacia jurema, 468 arbor vitce. 462 487 red 254 acalypha, . 465 arbutus, trailing, 774 violet, .... 254 acanthus, . 473 areca catechu, 473 white, .... 254 achillea, . . 473 arnica flowers, 46S yellow 254 aconite leaves, 468 arnica root, 47i Fires, colored, . . 252 aconite root, . 459 aromatics, . 469 colored, liquid, 255 actrea alba, 461 arrow wood, . 476 Fireweed, fl. extract, 461 actcea rubra, . 461 artemisia abrotan'm ,468 Fish berries, fl. ext., 461 adansonia, . 468 artemisia frigida, 468 glue, .... 513 adiantum, . 473 artemisia vulgaris, 468 oils, 641 adrue, . . . 474 arum triphyllum Fit, root, fl. extract, 469 adstringens, . 468 (wild turnip), 465, 487 Five finger, fl. ext., 469 resculus glabra, 468 asafetida, . 494 flowered gentian, 474 assculus hippocas asarum, 461 fl. extract, . 474 tanum, . 468 asclepias cornuti, 461 Fixed oils, 637 agaric, white, . 461 asclepias curassa- Flag blue. fl. ext., 487 agaricus albus, 461 vica, .... 468 sweet, fl. extract, 459 agrimonia, 473 asclepias incarnata 461 Flames, colored, 255 ailanthus, . 46 8,487 asclepias tuberosa, Flavor, cachou, . . 435 akasga, 461 (white root), 461 4S7 Plavored syrup, . 830 alder, black, . 476 ash, black, 474 Plavoring elixir, 275 alder, tag, . 468 ash, prickly, . 460 elixir, soluble, 277 alkanet, 461' ash, prickly, south- extracts, 408 aletris, . . 47 3, 487 ern, .... 469 extracts, soluble, 421 alligator pear, 475 ash wafer, . 469, 487 Havana cigar, 435 allium, . . . 479 ash, white, . . 474 prepared, . 277 allspice, . . 462 asimina triloba, . 465 sarsaparilla, 415 , 816 allspice, Carolina, 465 asparagus, . 473 Flavors, cordial, 439 alnus, rubra, . 468 aspidium, . 461 fruit, artificial, 427 aloes, 493 aspidosperma, 465 liquor, . 1184 to 1 1 90 aloes and myrrh, 494 aster, punicus, 473 Flaxseed oil, . 638 alstonia constricta , 461 aurantii dulcis, 473 Fleabane, fluid ext., 461 alstonia scholaris, 461 aurantii, amari, . 466 oil 647 altha-a flowers, 473 Australian bitter tincture, 948 althrea root, 468 bark, .... 461 Fleming's tincture of alum root, . . 475 ava kava, . 462 aconite, . 883 amber or ambrett 2, 462 avena sativa, . 461 Flies, to prevent ambrosia, . 473 avens, European, 474 lighting, . . 1171 ampelospsis, . 473 avens, water, . 474 Flexible coilodion, . 243 amygdalus persic a azedarach, . 461 Floral cologne, . "57 (peach l'ves), 4, 3.487 baccharis pilularis, 465 Florida water, 1158 anagallis arvensis 473 bael fruit, . 489 Flour paste, good, . 1 167 anchusa, 461 balm, lemon or Flowers, odors of, . "54 andira, . 473 sweet, . . 475 Foam, sea, 1 144 anemone, . 473 balm of Gilead soda, .... S49 anemopsis, 46S buds, . 462, 487 Frangipanni, ext. "55 anethum, . 468 balmony, . . . 473 sachet "59 angelica, 461 balsam of fir tree, 473 Freckle lotion, . . 1 148 angustura, . 468 bamboo brier, 476 Fluid, Condy's, . . 586 anise, . . . 468 baneberry, red, . 461 INDEX. 1231 Fluid ext. baobab, 46S Fluid ext. buckbean 475 Fluid ext. cascarilla, 465 baptisia, . 461, 487 buckeye, . . 46S cassia 461 barberry, . 468 buckhorn brake, 47 = castanea, 477 barley malt, . 475 buckthorn bark, 477 castor oil beans, . 462 bayberry, . 462 buckthorn berries 476 castor oil leaves, . 476 bay laurel or bay bugle, bitter, . 474 catalpa, . . . 46S tree, . . . 469 bugleweed, . 475, 4S7 cataria 473 bearberry (uva ursi), 472 burdock, root or catechu, 495 bearsfoot, . 465, 4S7 seeds, 475 catnep or catmint, 473 bebeeru, 465 burweed spiney, 469 caulophyllum, 468 beech, American, 474 butternut, Ameri compound, . . 482 belladonna leaves 468 can, . . . 465 cayenne pepper, . 460 belladonna root, 459 butternut, Europe ceanothus Ameri- bell wort, . . 469 an, 475 canus, . . . 47S benne, . 469 button bush, . 473 cedron seed, 469 benzoin, 494 button snakeroot 475 celandine, garden, benzoin compounc i, 494 buxus sempervir .... 46S 4^7 berberis aquifoli ens, . 46S celastrus scandens, 473 urn, ... 46 8,487 cabbage, skunk celery, .... 461 berberis vulgaris, 465 (dracontium).4< ,8,487 centaury, Ameri- bergamot, wild, 469 cabbage, tree bark . 473 can 47" betel nut, . 473 cachinca, . 468 centaury, Europe- beth or birth root 462 cactus, . . 46 1, 4>7 an, .... 474 betony or betonica , 468 caffea, . 473 cephalanthus, . 473 betula lenta, . 473 caffea tosta, 473 cercis canadensis, 473 bidens bipinnata, 473 calabar bean, . 462 cereus, . 401 487 birch, . . . 473 calamus, . . 45') cetraria, 4 73 bistorta or bistort 473 calendula, . 46S cevadilla, . . . 462 bitter apple, 474 California laurel 476 chamomile, Roman . 473 bitter bugle, . 475 calisaya, 477 German, 469 bitter polygala, 476 calycanthus floridv 15,465 chekin or chequin. 469 bitter root, 468 cancer root, . 474 chelidoniummajus, bittersweet, 47 t, 474 canchalagua, . 474 .... 468 487 bittersweet, false 473 canella, 461 chelone, glabra, . 473 blackberry, 467 canker lettuce, 476 chenopodium, 461 blackberry comp 481 cannabis indica, 459 cherry, birch, . 473 blackroot, . 47 2, 487 cannabis sativa,4f 1.4-7 cherry, wild, . . 47S bladderwrack, 474 cantharides, 461 cherry, wild, de- blazing star, . 475 cantharides, ethe tannated. 481 blessed thistle, 473 rial, . 493 cherry, wild, comp. 485 blood tlower, . 468 cantharis vesicato chestnut leaves. . 477 bloodroot, . 460 ria, . . . 461 chestnut, horse. . 468 bloodroot acetic, 488 capsella, . . 461 chewstick, . . . 474 blue flag, . . 464 capsicum, . »'"' ( hieorium, . 474 boldus or boldo, 461 caraway seed, . 468 chicory, . . . 474 bogbean, . . 475 cardamom, 4'" chimaphila, . . 471 boletus laricis, 461 cardamom comp 482 china root, . . 474 boneset, . 47 ■ 474 canluusbenedictu », 473 chiococca, . . . 4 l,s borago or borage 473 carnauba, . 468 chionanthus, . 474 . r: boundon, 46] caroba, . 17-- chirata 47' box, . . 468 carophyllus, . 46] cbittem, . . . 47'' bray era, . . 459 carpenter's square 47'' chocolate, . 47'' broomtops, aque tarrota or carrot, 468 chrysophyllum, . ous, . 489 carthamus tincto ( 1. ely. sweet, . . 475 bryonia or bryony 461 rius, . . . 473 cicuta, . . i;i i:t buchu, . . . 466 carum carri, . agar tree. . bnchn and juniper carya alba, 473 dmicifuga, r with :icetate po- cacao, . . . 476 . imii ifuga, 1 omp. .--■ tassium, . 482 casca, 460. < Inchona, . . . 1:: buchu and 1'areira Bia amarga, 473 cinchona, aromatic, 482 brava, . . 482 cascara sa g rada cinchona, detannat. 479 buchu compound 482 • • • 473. 47 cinchona, 1 omp., 1232 INDEX. Fluid ext. cinnamon, 461 cinquefoil, . . . 469 cleaver's, . . . 474 clover, sweet, . 475 clover tops, red, . 476 cloves, . . . . 461 coca, .... 471 cocash ( aster puni . ) 473 cocculus Indicus, 461 cochlearia amora. 465 cochlearia (scurvy grass), ... 474 cockleburr, . . 469 coffee, . . 417, 473 cohosh, black, 460, 487 cohosh, black comp. 4S2 cohosh, blue, . . 468 cohosh, blue comp. 4S2 cohosh, red (bane- berry), . . . 461 cohosh, white, . 461 cola or kola . . 469 colchicum, root or seed, .... 466 collinsonia, 468, 4S7 colocynth apple, . 474 colocynth comp., 482 coltsfoot, . . . 476 columbo, . . . 471 columbo Americ'n 474 co.mfrey, . . . 476 comptonia, . . 474 conderango, . . 474 conium fruit, . . 471 conium leaves, . 474 convallaria, . . 461 convulvulus pan- duratus, . . . 474 coptis teeta, . . 474 coptis trifolia, . 474 corallorrhiza, . . 468 coral root, . . . 468 coriander seed, . 461 corn ergot or smut, 476 corn silk, . . . 476 corn snake root, . 469 cornus florida, . 471 cornus circinata, . 474 cornus sericea, . 474 corydalis, . 468, 487 corypha cerefera, 468 coto, .... 465 cotton root, 460, 4S7 couch grass root, . 479 cramp bark, . . 469 cranberry b'k, high, 469 cranesbill, . . . 471 crawley, . . . 468 creeping huckle- berry, . . . 476 crocus sativus, . 474 cubeb, .... 460 Fluid ext. cubeb, ethe Fluid ext. erigeron, 461 rial, .... 493 eryngium aquati- cucumis citrullus, 474 cum, . . 468, 487 cucumis pepo, 474 yuccsefolium, . 469 Culver's root, 472 ,487 eryngo, water, 468, 487 cuminum cyminum 468 erythroplceum, 465 cummin, 468 erythroxylon coca, 47i cunila mariana. 474 erythracea, . . 474 curcuma, . . . 461 erythrrea, centau- cynoglossum, . . 474 rium, 474 cyperus articulatus, 474 eucalyptus, 460 cypripedium, 460 487 euonymus, . 469, 487 damiana, 462 eupatorium, 471, 474 dandelion, 479 aromaticum, 474 dandelion comp., 433 perfoliatum, 471, 474 dandeli'n and rhu- purpureum, 474 barb, 482 euphorbia corollata, 461 dandelion and sar- hypericifolia, . 487 saparilla, 484 ipecacuanha, . 465 dandelion and senna 483 pilulifera, 465 datura stramonium, 487 euphrasia, . . . 474 delphinum consol., 461 evening primrose, delphinum staph., 461 .... 474, 487 digitalis, 467 eyebright, . #74 digitalis acetic, 488 fagus ferruginea, 474 digitalis, etherial, 493 false bittersweet, . 473 dill, 468 false gromwell, 469 dioscorea, . . . 461 unicorn, . 462 487 diospyros, . . 474 fennel seed, 469 dipterix, . . . 461 fennel, water, . 462 dirca palustris, . 474 fern, male, . . 461 dita bark, . 461 fern, sweet, 474 dittany, American, 474 fever bush, 462 dock, yellow, . 472 feverfew, . 476 dogwood, . 47i fever wort, . 476 Jamaica, 469 filix mas., . 462 swamp, . 474 fir balsam bark, . 473 dracontium, . . 468 fireweed, . . . 461 drimys winteria, . 461 fish berries, . . 461 drosera, 461 fit root 469 duboisia, 468 five finger, 469 dulcamara, . 471, 474 five flowered gen- dwarf elder, 473 tian, .... 474 elder, dwarf, . 473 flag, blue, . 464 487 elder flowers, . . 476 flag, sweet, 459 elecampane, . . 469 fleabane, . . . 461 elephantopus, 474 fceniculum, 469 elephant's foot, 474 foxglove, . 466 elm, slippery, . 476 foxglove, etherial, 493 ephedra, 465 frangula, 478 epigaea repens, 474 francisca uni flora, 469 epilobium, . 474 487 frankenia, . 474 487 epiphegus, . 474 frasera, .... 474 equisticum, 468 fraxinus Ameri- erechthites, 461 cana, .... 474 eremocarpus, 465 sambucifolia, . 474 ergota, . . 477 fringe tree, 474 487 ergot, . . 477 488 frostwort, . 475 ergot, acetic, fucus vesiculosus, 474 ergot, corn, 476 fumaria officinalis, 474 ergot, etherial, 493 fumatory, . 474 eriodictyon, 461, 4S7 galangal or galanga , 462 INDEX. 1233 Fluid ext. gale, sweet , 475 Fluid ext., helianthe- Fluid extract Indian galium, aperine, . 474 mum, 475 hemp, black, 46S galium verum, . 474 helianthus, . . 469 Indian hemp, white, 461 galla 474 hellebore, Ameri- Indian physic, 462 garden celandine, can, . . 460 4S7 Indian sarsaparill 1. 475 .... 46S 4S7 hellebore, black, .■ 469 Indian tobacco seed. 462 garget root, 469 4S7 hellebore, white, . 469 Indian turnip, 465,487 garlic 479 helleborus niger, . 469 indigo, wild, 46 1. 487 garrya Fremontii, 469 helonias, . 462 ,487 inula Helenium, 469 gaultheria, 474 helonias comp., . 483 ipecac or ipecacu gelsemium, 460 487 hemidesmus, . . 475 anha, 478 gentian, . . . 47i hemlock, 476 ipecac, American, 462 gentian, cornp., . 4S3 hemlock, water, . 471 ipecac, aqueous, 490 five flowered, . 474 hemp, Amer. 461 , 4S7 ipecac and senega , 483 gentiana quinque- hemp, Indian, 459 ipecacuanha spurge, 465 flora, .... 474 hemp. Indian, bl'k, 46S ipomc ea jalapa, 462 geranium, . 471 hemp, Indian, wh'e , 461 iris florentina, 462 geum rivale, . . 474 henbane leaves, . 467 iris versicolor, 464, 4S7 geum urbanum, . 474 henbane root, . 469 iron wood, . . 475 gillenia stipulacea, 462 henbane seeds, 462 ivy, American, 473 gillenia trifoliata, 462 hepatica, . . . 475 ivy, poison, . 462, 487 ginger, .... 460 heracleum, . . 475 jarborandi, 472 ginger, Jamaica, . 417 herba or yerba jacaranda caroba, 475 ginger leaf, 465 mansa, . . . 468 jalap or jalapa, 462 ginseng, . . . 475 heuchera, . 475 jalap and rhubarb , 483 glycyrrhiza, 471 hibiscus abelmos- jalap and senna, 483 gnaphalium, . . 474 chus 462 jalap, wild, 474 golden rod, . . 476 hickory, white, 473 Jamaica ginger, 417 golden seal, 464 hippocastanum, . 475 jasmine, yellow gold'nseal, aqueous .490 hoarhound, 475 (gelsemium), 460, 487 gold thread, . 474 hoarhound comp., 483 jeffersonia diaphylla, 475 gossypium, 460, 487 Honduras bark, . 473 Jersey tea, . . 473 gouania domingen- hops, .... 462 johnswort, . . 475 sis 474 hoptree, . . . 469 judas tree, . . 473 granati fructus cor- horse chestnut bark 475 juglans cineria, 465, 4S7 tex 474 horse chestn't seeds 46S juglans nigra. . 475 granatum, . 474 horsemint, . . 469 juglans regia, . 475 grape, Oregon, 468, 487 horseradish, . . 4 f >5 kalmia latifolia, 475 gratiola officinalis, 474 horsetail, . 468 kamala or kameete , 4' '2 gravel plant, . . 474 hound's tongue, . 474 kava kava, 462 great laurel, . . 469 humulus, . 462 kidney leaf, 462 green ozier, . . 474 hydrangea, 475 kidney root, 465 grindelia comp., . 483 hydrastis, . 4(14 480 kino, . . 495 grindelia robusta, hydrastis, aqueous, 490 kola nut, 469 .... 464 487 hydrastis, purified, 480 kousso, . 459 grindelia squarrosa, 487 hydrastis, without krameria, . 472 gromwell, false, . 469 alcohol, . ,.,,, Labrador tea, . 469 guaco leaves, . 474 hyoscyami folia, . 467 lactucarium, 17- guaiac resin, . . 495 hyoscyami radix, 469 lactuca virosa, 475 guaiac wood, . . 462 hyoscyami semen, 462 lady's bedstraw, 474 guaiacum lignum, 462 hyoscyamus, . . 4f. 7 lady's slipper, 46 ». 487 guarana, 464 hypericum, . . 475 lappa, (root anc E ematoxylon, 474 hyssop or hyssopus, 475 Beeds), 475 hriir cap moss, 476 Iceland moss, 473 large Rowerinj hamamelidis cortex 474 ice plant, . r -. spurge, . . . |6l hamamelis bark, . 474 ignatia, 4^2 480 large Bpotte* hamamelis leaves, 478 ilix Paraguayensis, 475 spurge, . r- hard hack, . 476 illicium, . . . 469 larix Americana, . 475 haw, black, 467 ■1-7 Imperatoria, 462 larkspur seed. 461 hazel, witch, 474 478 Indian bad, . |8g laurel, K rcat . • ■ '69 hedeoma, . . . 469 Indian cannabis, , laurel, mountain, . 17-- hedge hysop, . . 474 Indian hemp, . 459 laurUS, nobilis, 1234 I. YD EX. fluid ext. lavendula Eluid ext. manzanita, 469 Fluid ext. nympha;a or lavender, . 475 marigold, . 468 odorata, . . . 469 leaf cup, . . 465, 487 marjoram, sweet, 475 oak, poison, 462 487 leatherwood, . 474 marjoram, wild, . 469 oak, white, . . 476 ledum palustre, 469 majorana, . 475 oats, common, . 461 lemon peel, 475 marrubium, 475 Oenothera biennis, leonurus cardiaca 475 marsh mallow, 468 (eve. primrose) 475,487 leptandra, . 472, 487 marsh mallow root 473 onosmodium, . 469 lettuce, wild, . 475 marsh rosemary, . 476 opium, .... 496 levisticum, . 462 marunta cotula, . 475 opium, aqueous, . 491 liatris ordoratissi masterwort, . 462 475 orris root, . 462 ma, . 475 matico, .... 467 opium, camphorat'd,496 liatris spicata, 475 matico comp. . 4S4 opium, deodorized, 496 liatris squarrosa, 475 matricaria, 469 orange peel, bitter, 466 life everlasting, 474 May apple, 464 orange peel, sweet, 473 life root, . . 476, 487 May weed, . . 475 Oregon grape, 468 487 lily of the valley, 461 melilotus or melilot 475 origanum, . 469 lily, white pond, 469 melissa, 475 osmorrhiza, . . 475 lily, yellow pond 469 menispermum, 405 osmunda, . . 475 limonis cortex, 475 mentha piperita, . 475 ostrya Virginica, . 475 linden, . 476 mentha viridis, 475 oxydendron, . 475 lindera, . 462 menyanthes, . 475 ozier, green, . 474 lippia Mexicana, 462 mercurialis annua, 465 palmetto saw ber- liquidambar, . 462 mercury herb, 465 ries 469 liquorice, . . 47i mercury weed, 465 panax, .... 475 liquorice, aqueous . 49i methysticum, . . 462 pansy, wild, 476 liquorice, comp., 483 mezereum, 460 papaver, . . . 475 liquorice, ext., 495 micromeria, . . 462 papaw, . 465 liriodendron, . 462 mikania guaco, 475 Paraguay tea, 475 liverwort, . 475 mistletoe, . 476 paregoric, concent'd,4g6 lobelia, 462, 472, 487 mistletoe, Amer. 475 Pareira, 472 lobelia, acetic, 488 mitchella, . 475 parilla, yellow, 465 lobelia, comp., 483 mitchella comp. . 484 parsley seed, . 462 lobelia seed, . 472 monarda fistulosa, 469 parsley root, . . 475 locust, . . . 469 monarda punctata, 469 partridgeberry, . 475 logwood. 474 monesia, . . . 468 partridgeberry com 484 lovage, . 462 monkshood, 468 paullinia (guarana) 464 lungwort, . 476 monotropa uniflora 469 peach leaves, 473 487 lupulin, . . . 460 morus nigra, . 475 pear, alligator, 475 lycopus Europreus , 475 motherwort, 475 pea, turkey, 468 487 lycopus Virgini mountain laurel, . 475 pellitory, 462 cus, . . 475, 487 mountain mint, . 469 pennyroyal, . . 469 mace, 462 mountain sage, . 468 penthorium sedoides, macrotys racemo mugwort, . 468 (V. stonecrop) 469, 487 sa, . . 460, 487 mulberry, . 475 peony, .... 469 madder, 476 mullein, 476 pepo, .... 475 magnolia, . . 462 musk root, . . 462 pepper, black, 462 maidenhair fern, 473 myrica, .... 462 pepper, cayenne or male fern, . 461 myrica gale, . 475 red, . . . 460 mallow, common 475 myristica fragrans, 462 pepper, water, 465 487 maltum or malt, 475 myrrh, .... 495 peppermint, 475 malva sylvestris, 475 myrtus checan, 469 persia gratissima, 475 manaca, 469 nectandra, . . . 465 persimmon, fruit 01 mancona bark, 465 nepeta cataria, 473 bark, 474 mandrake, . 464 nervine, American, 460 petroselinum, 462 475 mandrake comp. , 484 nettle, .... 476 peumus boldus, . 462 mangifera Indica 475 night-blooming ce- phellandrium, 462 469 mango, . 475 reus, . . 461 487 phoradendron, 475 mangostana, . 475 nuphar advena, . 469 physic, Indian, . 462 mangosteen, . 475 nutgall, 474 physostigma, . . 462 mansa, yerba r nutmeg, . . . 462 Phytolacca, 469, 487 herba, 465 nux vomica, . 464 pill-bearing spurge, 465 INDEX. 1235 Fluid ext. pilocarpus, 472 Fluid ext. pulsatilla, 469 Fluid ext. sabadilla. 462 pimenta, 462 pumpkin seed, 474 sabbatia angularis, 476 pimpernel or pim- pyenanthemum, . 469 sabbatia Elliottii, 476 pinella, . 462 pyrethrum, 462 sabina 460 pimpernel, scarlet, 473 pyrethrum parthe- sabul serrulata, . 469 pine, white, 475 nium, 476 saftlower, . 473 pink root, . 472 pyrola rotundifolia, 476 saffron, American, 473 pink and senna, . 434 pyrus malus, . 476 saffron, true, . . 474 pinus Canadensis, 476 quassia, 472 sage 476 pinus strobus, 475 quebracho, 4"5 sage, mountain, 468 piper methysticum, 462 queensroot, 472 487 St. Johnswort, 475 piper nigrum, 462 queen of meadow, 474 salix alba, . 469 pipsissewa, 471 quercus alba, . 476 salix nigra, 4'"! piscidia, 469 quillaia, 469 salvia, .... 476 pitcher plant, . 476 quince, Bengal, . 489 sambucus. 476 plantain, common, 476 quinine bush, . . 469 sanguinaria, . 400 plantigo major, . 476 quinine flower, 476 sanguiniaria, acet.. 488 pleurisy root, 461, 4S7 ragweed, 473 santal, white or yel- podophyllum, . 464 raspberry leaves, . 476 low, .... 462 pieonia officinalis, 469 red bark, . . . 477 satanum citrinum, 41-2 poison oak or ivy, red cloverheads, . 476 santalum rubrum, 462 .... 462 487 red root, 478 santonica, . 462 poke root, . 469, 4S7 red saunders, . 462 saponaria, . . . 469 poke root comp. . 484 rhamnus catharti- sarothamnusscop., 489 polemonium rep- cus, .... 476 sarracenia purpurea 47" tans 469 rhamnus frangula, 477 sarsaparilla, . . 47S polygala amara, 475 .47" rhamnus prushia- sarsaparilla.Amer. 473 polygala bitter, 476 na, . 473, 476 490 sarsaparilla and polygonatum g i - rhatany, 472 dandelion, . 484 ganteum, 469 rheum 467 sarsaparilla comp. 484 polygonum puncta- rhododendron maxi .469 sarsaparilla, Ind'n, 475 tum, . . 465 487 rhoeas, . 476 sassa bark, 465 polymnia uvadelia, rhubarb, 467 sassafras, . 4"5 • ... 465 487 rhubarb, aromatic, 4S4 satureja, 469 polypodium or poly rhubarb and dan- saunders, red, 4*'2 pody, . . . 476 delion. . . . 482 savine 460 polytrichum, , 476 rhubarb and jalap, 4S3 saxafrage, small, 462 pomegranate, . . 474 rhubarb and senna, 4S4 scilla, .... 460 pond lily, white, . V") rhus aromatic, 469, 487 scilla, acetic, . 488 pond lily, yellow, 469 rhus glabra, 472 scilla compound, 485 poplar, white, 4<") rhus toxicoden- scrofularia nodosa, 47'' poppy, .... 475 dron, . . 462 487 scullcap, . . 473 487 poppy, red, . . 47" richweed, . 473 scullcap comp., . 4S5 populus albus, 469 ricinus leaves, 476 scurvy .^rass, . 474 populus candicans, ricinus seeds, . . 462 Scutellaria, . 47S 4S7 . . . 4''2 487 robina 469 seawrack, . 474 potentilla Cana- rockrose, . . . 475 senecio, . 47(1 4S7 densis, 469 rose, .... 472 senega or seneka . r: potentilla tormen- rosemary, . 476 senega, aqueous, 491 tilla 469 rosemary, marsh, 476 senega and ipecac, r | prickly ash bark, . 40O rosin weed, . . . 4''-' senna, .... prickly ash berries, 462 rottlera, 402 senna alcoholized, 480 prickly-ash, south- ruliia 476 senna and dande- ern, . . 473 rubus strigOSUS, . 476 lion pride of India, 461 rtibus villosus, 4' <: senna and jalap, . »8 3 primrose, evening, rudbeckia, . . . 476 Senna and pink r't. 4S4 • ... 474 487 rue 476 senna and rhub'rb 484 prinos 47'- rumex, .... 472 senna, aqueous, . wa prunus Virginius, 478 rumex comp., . 434 senna, comp., ptelea trifoliata, rush, scouring, 468 senna, purified, . . . . . 469 487 rata graveolens, . 47'' serpentaria, . . pulmonaria, . . 476 rye, smut or spurred 477 unum, 469 V2M INDEX. Fluid ext. seven barks ,475 Fluid ext. stramoni Fluid ext. tussilago, 476 shepherd's purse, 461 um, green plant 487 twin leaf, . 475 silkweed, . . . 461 strychnos ignatia 462 ulmus fulva, . 476 silphium, . . . 462 sumach, 472 umbellaria, . . 476 simaba cedron, 469 sumach, aromatic unicorn, 487 simaruba, . 476 . . . . 469, 487 unicorn, false, 462 487 skoke or poke root, sumach, Chinese 487 urechites suberecta, 462 .... 469, 4S7 sumbul, . . 462 urtica dioica, . . 476 skunk cabbage, summer savory. 469 ustilago, maydis, 476 468, 469, 487 sundew, 462 uva ursi, . . . 472 slippery elm, . . 476 sunflower, . 469 uvalaria perfoliata, 469 smart weed, 465 swamp dogwood 474 vaccinum crassifol- smilax sarsapar., . 476 sweet balm, 475 ium 476 snakehead, 473 sweet cicely, . 475 valerian, 467 snakeroot, button, 475 sweet clover, . 475 valerian Amer. , . 460 snakeroot, Canada, 461 sweet fern, 474 vanilla, . . 419 480 snakeroot, corn, . 469 sweet flag, . . 459 vanilla plant, . . 475 snakeroot, Virg., 464 sweet gum tree. 462 veratrum sabadilla, 462 snakeroot, white, 474 sweet marjoram, 475 veratrum album, . 469 snakeweed, 473 sweet orange, . 473 veratrum v i r i d e, soap tree bark, 469 symplocarpus, 46 3, 487 . . . . 460, 487 soapwort, . . . 469 Symphytum offici verbascum thapsus, 476 solidago, , . . 476 nale, . . . 476 verbena hastata, . 476 Solomon's seal, . 469 tabacum, . . 476 vervain, 476 sourwood, . 475 tag alder, . . 46 S viburnum dentatum 476 Spanish needles, 473 tamarack, . . 475 viburnum opulus, 469 spearmint, . 475 tanacetum, 476 viburnum punifol- spicewood, 462 tansy, . . . 476 ium, . . 467 487 spigela, . . . 472 taraxacum, . ' 479 viola tricolor, . . 476 spikenard, . . . 473 tea 476 Virg. creeper, 469 473 spikenard comp. , 485 tea, Labrador, 469 viscum album, . 476 spiney burweed, . 469 tecoma radicans, 476 wafer ash, . 469, 487 spirre tomentosa, 476 thea Chinensis, 476 wahoo bark, 469 487 spurge, ipecacuanha, 465 theobroma cacao 476 water eryngo, 468 487 spurge, large, flow- thimbleweed, . 476 water fennel, 462 469 ering, . . . 461 thistle blessed, 473 watermelon seed, 474 spurge, large, thoroughwort, 471 water pepper, 465 487 spotted, . 465, 487 thuja Occident wax palm, . 468 spurge, pill-bearing, 465 alis, . . . 46 2, 487 whiteroot, . 461 spurred or smut rye 477 thyme, . . . 476 white wood, 462 square, carpenter's, 476 thymus vulgaris, 476 wickup, . 474, 487 squaw vine, 475 tilia, . . . 476 wild cherry, 478 squaw vine comp., 484 tobacco, 476 wild cherry comp., 485 squill, .... 460 tolu, . . . 497 wild cherry, detan- squill, acetic, . . 488 tonga, . 476 nated, . . 481 squill, comp., 485 tonqua, 461 wild indigo, 461 487 staff tree, . . . 473 tormentil, . 46 9. 476 wild lettuce, 475 staphisagria, . 461 tormentilla, 476 wild turnip, 465 star anise, . 469 trailing arbutus. 474 wild violet, 476 star, blazing, . 475 tree of heaven, 468 wild yam, . 461 star grass, . 473 487 trifolium partense , 476 willow black, . . 469 statice Carolina, . 476 triosteum perfoli willow herb, . . 474 stavesacre, . . 462 atum, 476 willow white, . 469 sterculia accumin, 469 trillium. 462 wintera or winter's 462 stigmata maydis, 476 triticum repens, bark, 462 stillingia, . 472 . 4S7 trumpet creeper, 476 wintergreen, . 474 stillingia, comp. . 4S5 tulip tree, . 462 witch hazel, 474 478 stone crop, Vir- turkey, corn wood anemone, . 473 ginia, . . 469, 487 pea, . . 46 8, 487 wormseed, . 461 462 stone root, . 468 , 4^7 turmeric, . . 461 wormwood, . . 473 stramonium leaves Turnera, . 462 xanthium s pi no- . ... 467 , 468 turnip, wild, 46 5, 4S7 sum 469 INDEX. 1237 Fluid ext. xanthium Foods »., Fruit, red, cochineal, 247 strumarium, 469 infants and inva- saline 1116 xanthoxylum bark, 460 lids, .... 1172 syrups, .... 777 xanthoxlum, ber- Formate of ammoni- tablets, .... 872 ries 462 um, .... 149 Fuchsine, 154 yarrow. 473 amyl I 5 I Fucus vesiculosus fl. yam, wild, . . . 461 Formic, acid, 56 ext 474 yellow dock, 472 4S4 acid spirit, . . . 766 Fuller's leg wash, . 597 yellow jasmine, . 460 ether, .... 7S Fumaria fl. ext., 474 yellow parilla, 465 Fortified ex. vanilla, 420 Fumitory fl. ext.. . 474 yellow root, 469 Fossil bitumen, . 724 Fumigating powder, 721 yerba buena, . 462 Fothergill's asthma Fumitory syrup, 824 yerba mansa, . 465 mixture, . . . 628 Furniture cream, 11S1 yerba rheuma, 474 487 Fousel oil, . 86, 95 150 polish, .... 1181 yerba santa, 461 487 Fowler's solution, . 565 varnish, "93 zanthorrhiza, . 469 Foxglove, fl. ex., 466 Fusel oil, . . 86, 95 150 zedoaria or zedoary 462 fl. ex. etherial, 493 Fusible metal, . . 191 zingiber, 460 ointment, . . . 992 Fustic extract, . 877 Fluid extracts, . . 453 syrup, .... S25 acetic 4S8 tincture, 905 aqueous, 489 Francisca uniflora, G class A, formula, 453 fl. ext., . . . 469 class B, 463 Fragrant benzine, . 1169 Gadberry's spleen class C, 465 cream, .... "33 mixture, . 630 class I J, " 470 Frangula elixir, . 325 Gadus morrhua, . . 638 compound, . . 481 extract, .... 449 Galactose, . 515 735 etherial, 492 fluid extract, . . 478 (ialangal, fluid ext. 462 green plant, . 466 Frankenia, fl. ext. 474 ,4S7 oil 652 official, 459, 464, 466, Frankincense, . . 730 tincture, 947 470, 477- Frasera, fl. ext., 474 Galbanum, . . . 729 gums and resins, 493 Fraxinus, Am. fl. ext. .474 plaster 3S6 processes for, 455 to 458 sambucifolia fl. ext. ,474 tincture, 946 U.S. 1 S 70 process 455 Frazerin, .... 732 Galena 696 U. S. 1880 process . 455 Freckle and moth Galen's cerate, . 224 combination proc, 457 lotion, . . . 597 Gale, sweet, tl. ext. 47? pressure process, 457 French blacking, 117S Galium aperine, tl. repercolat'n proc, 456 French brandy, 771, 1187 extract, . 474 water-bath percol., 458 Fresh herbs, tinct., 913 verum, fluid ext. 474 E luid Hydrastis, 480 490 Friar's balsam, . . 890 Galla, fluid extract, 474 writing, . . . 1 1 74 Friedrichshall water Gallate ammonium, 149 1 ilming, 5f>9 solution, 869 Gallic acid, . . 57 ,873 battery, 586 Fringe tree, fl. ext., acid, glyeerite, . 517 ink erasing, 1178 . • ■ • 474 4S7 acid, ointment. 970 Fluoride of ammoni- Frostilla "33 ( rails syrup, . 823 um 149 Frost wort, fl. ext., 475 Gambogia, 729 of antimony, . . ' 59 Fruit 21 < lambogic acid, . 729 of calcium, 209 acid 849 ( tarcinia 1 [anburii, . 7-"' of chromium, . 239 coloring, . . 247 ( tardea celandine, ll. Fluorides, . . . 513 flavors, artificial, 427 extract, . v>- . 4T Fluorine 5i3 or grape salt, . . 1 1 16 Garget root, tl. ext., Fluor-spar, . . . 209 juice preservative, 1183 .... 469 ■ I-- Flower pomades, i ( > . 645 juices 776 1 largling oil, . r.096 Flowers 20 juices, process for i rarlic, Quid ext., 4-w 1' ly paper, poison, . 230 making, . 776 oil 652 sticky, . . 231, 1170 juice, shakes, . 865 oil, artificial, . . 134 Fly stone, . . . 240 juice, syrups, . . 849 ointment, . powder, 721 laxatives, . . . syrup Foam soda, . . . 849 laxative lozenges, syrup, compound, 794 Fosniculum H. ex., . 469 oils from, . . . 642 Fremontii, il. Food, chemical, B4£ preserving liquids, extract, . . . 1058 preserving solu- Gas, laughing, . 635 plant 1 1 72 tions. 59° Liquor [46 1288 INDEX. Gasoline, .... 671 Gentian and tinct. of Glace, starch, IT83 Gaultheria, fluid ext. 474 iron elixir, with Glass liquid, . . . 567 spirit, .... 767 lactopeptine, . 332 and metal cement, 1 164 Gaulthero-sal i c y 1 i c wine compound, 1014 polish 1181 acid. . . 648, 737 Geraniin, . . . 732 varnish, "93 Gaultherilene, 648 Geranium, fl. extrac , 471 water 567 Gelacacia or soluble Geranium oil, 652 Glauber's salt, . . 755 pill coating, 682 tincture, 946 Globules, medicated, 957 Gelatin 513 German cologne, "57 Gloss, hair, . . . 1 149 Gelatina, .... 513 corn cure, . 24^ , 1059 starch 1182 Gelatin capsules. 514 liver bitters, . 104 1 Glove cleaner, 1 169 coating, 514 silver, . . . 264 Glucose, . . . 152, 515 coating pills, . 681 syrup, . . . 106.4 Glucoses 735 suppositories, . 514 tonic, . . . 1118 Glucosides, . 515 Gelsemin, 732 Geum urbanum, fl.ext. 474 Glue 513 Gelsemina, 116 rivale, fl. extract, 474 elastic, .... 1165 Gelsemine, . . . 116 Gewtirzhafte krauter , 758 liquid, . . 514, 1165 hydrochlorate, 117 Giant liver pills, 1051 marine, . . . 1165 Gelseminia, . . . 116 Gilding and silvering mouth, .... "65 Gelsemium, elixir, . 326 pills, . . . 682 ordinary, . 1165 extract, alcoholic. 446 solution, . . 11S1 pad, 1165 fluid extract, 460, 4S7 wax, 216 tungstic, 967 tincture, 909 Gilead balm, . 182 waterproof, 1165 General formula for Gillenia stipulacea fl Glutina cement, . 1163 extracts. . . . 442 ext., . 462 Glyceric alcohol, 85 , 516 soluble extracts. . 421 trifoliata fl. ext., 462 Glycerin 5i6 Gentian and bismuth Gillinia syrup, 823 and cod liver oil, 404 elixir, 327 Gin, .... 1 190 cream, .... 1 194 and chloride iron American, . . 1 190 honey 1147 elix. with quini. 33i Holland, . . 1191 honey, carbolated, 1147 chloride iron, qui- London cordial, 1191 ice, 1147 nine and strych- London dock. 1191 jelly, . . . . 1147 nine, elixir, 33i Old Tom, . . 1191 jelly, camphorat'd, "47 compound, fl. ext. 483 to clarify, . 1191 jelly, carbolated, "47 tincture, . . 910 to filter,' . . 1191 lotion "49 tinct. improved, 911 Ginger ale, . . 422 ointment, . . . 977 cordial, .... 262 ale extract, 422 soap 743 elixir, .... 326 ale syrup, . 422, 856 solidified, . "47 ferrated, . . 327 carminative, 1046 Glycerina, 517 extract, .... 446 elixir, . . . 332 Glycerines, 517 five-flowered , fl. ext. 474 extract, aromatic 1074 Glycerinum, . 5i6 fluid extract, . 471 extract or essence 417 acidi carbolici, 517 infusion comp., . 537 extract, Jamaica, 1073 acidi gallici, 517 and iron elixir, 327 329 fluid extract, . 460 acidi tannici. . 517 iron and bismuth grass oil, . . 652 aluminis, . 517 elixir, 328 Jamaica essence 1073 amyli 5i8 iron, bismuth and Jamaica extract. 1073 boracis, . . . 5i8 strychnine elix. 32S Jamaica extract plumbi subacetatis 5i8 iron and strychnine aromatic, 1074 tragacanthae, . . 5i8 elixir, . . . 329 leaf fl. ext., . 465 vitelli 519 iron and strychnine oil 652 Glycerita, 517 elixir, . . . 32S oleoresin, . 661 Glycerite albumen, . 519 and phosphate of plaster, . 393 of alum, 517 iron elixir, . 329 soluble extract, 421 arnica 519 strychnine and bis- syrup, . 422, S2 1, 856 bismuth, . . . 519 muth elixir, 330 tincture, . . 945 of borax, 518 and strychnine elix. 33o tincture, strong, 945 calendula, . 520 tincture, 910 tonic, 1118 camphor chloral. . 520 tinct. ammoniated. 950 troches, . . 966 carbolate of iodine 520 tinct. compound, 910 Ginseng fl. ext., 475 carbolic acid, . 517 with tinct. of iron Girondin disinfectant gallic acid, 517 elixir, 330 solution, 5S7 hypophosphites, . 520 INDEX. 1239 Glycerite iodine, 521 pepsin 521 of pepsin and wa- fer ash, . . . 521 phosphorus, . . 5 21 of quinine, 521 of quinine and strychnine, . 522 of starch, . . . 518 subacetate of lead, 519 tannic acid, 517 of tar, .... 522 of tar compound, 522 tragacanth, 518 yerba santa comp. , 522 yolk of egg, . . 519 Glycerites, . . . 517 Glyceritum amyli, . 518 Glycerol, .... 5i6 Glyceryl, .... 5i6 Glyconin 519 Glycyrrhiza elixir, . 342 elixir compound, . 343 extract, pure, . . 446 fluid extract, . . 471 mixture comp., . 624 powder comp., 716 syrup 822 syrup compound, 827 Glycyrrhizin, ammo- niated, . . . 523 Glycyrrhizinum, am- moniatum, . 523 Gnaphalium, fl. ext., 474 Gnoscopine, . 666 Gold, . . . 179 bromide, 180 chloride, 180 cyanide, 180 ink, . 1 177 iodide, . 180 leaf, . . . 179 264 Mannheim, ointment, . 992 oxides. . . 180 plating solution, . 590 andsodi'm chloride . 179 sulphide, . . . 180 thread, fluid ext., 494 thread, tincture, . <)46 white, .... 695 i lolden anodyne tinct. [028 drops, 1 >r. 1 »e 1 a Motte's, . . . 381 hair coloring, . IO-I ointment, . 1 103 rod, fluid extract, 476 rod, oil, 652 seal elixir, . 334 seal, fluid extract, 464 seal, fl. ext., aque., 490 seal tincture, 914 Golden seal wine comp., . . . 1014 syrup, .... 874 tincture, . . . 102S Gombault's caustic balsam, . . . 1034 Gooseberry essence or extract, . . . 430 Goose oil, . . . 641 Gossypiin, . . . 732 Gossypium fl. ext., . . . 460, 487 Gossypium herbacum, 638 wine, .... 1010 Gouania domingensis, 474 Goulard's balsam, . 1S5 cerate 221 extract 563 Gould's d i a r r h ce a mixture, . . . 629 Gout cordial, War- ner's, . . . 936 elixir 3S0 mixture, Lavelle's, 629 paper, .... 230 Government harness dressing, . .1179 Gowland's lotion, . 597 Granati fructus fluid extract, . . . 474 Granatum fl. ext., . 474 Grantville carbolic alkali, . . . 587 Granulated citrate of magnesia, . Coo zinc 1020 Granville's milder lo- tion, .... 597 stronger lotion, . 597 Grape essence or ext. , 430 or fruit salt, . .1116 Oregon fl. ext., 468, 487 phosphate syrup, 856 sugar, . 152, 515. 735 syrup, . . 850, 856 Graphite, .... 210 Grass-green coloring, 248 Gratiola, fluid ext., 474 Gravel plant, fl. ext., 474 Grease, bear's, . . 64] Great laurel. II. ext., 4'") Green show bottle . 251 balsam, . . l8l, l8j coloring, 248 hellebore, tinct., . 944 ink [173 iodide mercury, . 527 , fluid ext., . 471 plant, fluid cxts., .| -1. soap 742 soap, tincture, g )8 tinctures, . Gregory's powder, Griffith's mixture, Grindelia, fluid ext compound, . robusta, elixir, fluid extract, 464, 487 squarrosa, fl. ext. , 4S7 Gromwell, false, fl extract, . Ground-nut oil, . Guaco leaves, fl. ext Guaiacene, Guaiacic acid, Guaiac, liquid ext., resin, ... resin, fluid extract tincture, tincture alkaline ammoniated, tincture, Dewee's wood, fluid ext., Guaiacol, . Guaiacum balsam, lignum, fluid ext. mixture, officinale, . syrup, . wood, tincture Guarana elixir, and celery elixir fluid extract, syrup, . . tincture, Guarananine, Gum aloes, ammoniac, . amine, . . arabic, . arabic syrup, artificial, bdellium, . British, . . camphor, . catechu, cherry tree, copal, . cutch, . . euphorbium, fetida, . . galbanum, . gamboge, . tc, , hemlock, hog, . . . kino, mastic, . mesquit, myrrh, . . ohbanum, . opium, . opoponax, . resins, . 2 474 725 725 495 725 495 911 912 912 912 462 725 185 462 625 725 S24 94S 332 333 464 825 947 no 727 728 724 726 792 271 729 271 727 727 727 725 727 729 728 729 729 725 694 727 727 726 727 73o 728 73" 1240 INDEX. sagepanum, 730 Hall's solution of Hemlock, essence, 412 sandarach, 726 strychnine, 591 fl. ext 476 Senegal, . . 726 Halogens, . 513 , 540 gum, . . . 694 spruce, . 730 Hamamelidin, 732 juice, 775 sweet, . 182 Hamamelidis cortex, oil, .... 652 tamarac, . . 730 fl. extract., . 474 pitch, . . . 694 thus, . . . 182 Hamamelis, bark, fl. pitch plaster, . 388 tragacanth, 727 extract, . 474 tincture, 904 turpentine, 182, 662 leaves, fl. extract, 478 water, fl. ext., 471 Gummipulver, 717 Hamburg tea, . . 1 107 Hemorrhoidal lotior . 597 Gums, . . 21, 722, 726 Hamburger drops, . 1126 Hemp, American, fl chewing, 730 Handkerchief exts. , "54 ext., . . 46 1, 487 Gun cotton, soluble 721 perfumes, . "50 Indian, black, fl Gurjun balsam, iS 2, 663 Hardhack, fl. ext., 476 ext., . . . 468 balsam oil, 652 Harness dressing, Indian, fl. ext., 459 Guttapercha, 725 government, "79 Indian tincture, 893 solution, 558 polish, .... 1180 Indian, white, fl Gypsum, . 210 Hartshorn, . . . 145 ext., . 461 Hasting's wood, seed oil, 642 naphtha, . . 772 Henbane, extract, 447 H Havana cigar flavor- leaves, fl. ext., 467 ing, .... 435 root, fl. ext., . 469 Haarlem oil, . 653 Haw, black, fl. ext., 487 seed, fl. ext., . 462 Haematoxylon, fl. ex t. 474 Hazel-nut. oil, . 662 syrup, . . . 825 Hair balsam, 1081 witch, fl. ext., 478 474 tincture. 9 T 5 cap moss, fl. ext., 476 Healing ointment, 1 104 Henry's magnesia, 599 dye, bismuth, . 1141 Health elixir, . . 381 Hen's oil, . 641 dye, black, 1080 restorer, women's, 1077 Hepar sulphur, . 781 dye, brown, 1080 Heart corrector, 1085 sulphuris, . 781 dye, golden, . 1081 preparations, . 1084 sulphuris kalium, 781 dye, vanadium, 1141 regulator, . . . 1085 Hepatica, fl. ext., 475 dyes, 1141 Heave powder, . . 1057 Hepryl, . . . 85 gloss, . . . 1 149 Hebra's ointment, . 976 Heptyl alcohol, . 85 grower, "43 Hedeoma, fl. ext., 469 Heracleum, fl. ext. 475 grower, carboline 1084 Pledge garlic oil, 652 Herba or yerba man grower, pomade, "43 hyssop, fl. ext., . 474 sa, fl. ext., . 46S growers, 1142 hyssop, tincture, . 947 Herbs, . . . 21 lotion, . . . 1084 mustard syrup, 824 Heuchera, fl. ext., 475 lotion, almond, "43 Hektograph copying Hexyl, . . . 85 lotion, bay, "43 pad 11S0 alcohol, 85 lotion, rose, "43 inks "75 Hibiscus abelmos lotion, stimulating , "43 Helianthemus, fl. ex. 475 chus, fl. ext., 462 lotions. . "43 Helianthus, fl. ext., 469 Hickory-nut oil, 662 oil bases, •. 1141 Heliotrope oil, . 652 white, fl. ext., » 473 oil coloring, 1141 sachet "59 Hiera picra, . 720 oil perfumes, . 1 142 Hellebore, Ameri- High wine, . . 88 oil, walnut, 1142 can, fl. ext., 160 ,487 Hippocastanum, fl oils, .... 1141 American, tinct., 943 ext., . 475 powders, 1 146 black, fl. ext., . 469 Hips, .... 257 preparations, . 1 140 ointment, . 992 confection, 257 renewer, icSi white, fl. ext., 469 Hive syrup, . 817 renovator, . 1082 wine, comp., . 1014 Hoarhound com restorer, . . 10S2 Helleborus, niger, fl. pound, fl. ext. 483 restorer, Mrs. Al ext 4G9 compound syrup 828 len's, ■ 1083 Helminthocortus sy- fluid extract, . 475 tonic, katharion, 10S3 rup, .... 822 oil 652 tonics, . 1083 Helonias, fl. ext., 462, 487 syrup, . . . 823 vigor, . . . 1082 fl. ext., comp., 483 tar and honey, 1066 vitalizer, 1082 comp. elixir, . 333 Hock syrup, . 857 wash, 1084 Helonin 732 Hoffmann's anodyn -, 760 Haller's acid drops, 73 Hemidesmus, fl. ext., 475 balsamic mixture 628 acid elixir, 380 syrup, .... 803 balsam of life, 62S INDEX. 1241 vicerale elixir, 38 I, 343 Hungarian turpentine, 663 H ydrated oxide of Hog cholera cure, 1058 turpentine oil, 652 bismuth, . . . i95 powder, . . 1057 Hunn's life drops. 1127 oxide of iron, 507 Hog gum, 727 Hunyadijanos water, 869 oxide of tin, . 773 Holloway's pills, 1127 Husband's magnesia, 599 oxide of iron with Holzthee, . . . 75S Huxham's tincture, 901 magnesia, . . 508 Homoeopathic solu Hyacinth oil, 654 per oxide of tin, 773 tions, . . 955 Hydracides, . 533 Hydrates, . . . 667 triturations. 957 Hydramines, 96 of tin, . . . 773 tinctures, . 953 Hydrangea, fl. ext., 475 Hydride of phenyl, 1S9 Honduras bark, fl H ydrargy ri c h 1 r phosphorus, 674 ext 473 dumcorrosivum . 526 Hydrides, 532 Honey, balsam of, 1S4 chloridum mite, 525 carbon 213 borax, . 618 cyanidum, . 526 Hydriodate of morph. 122 clarified, . . 618 iodidum rubrum, 527 Hydriodic acid, . 540 cough, . 1063 iodidum viride, 528 acid diluted, . 50 glycerin, . . "47 oxidum flavum, 523 acid syrup, 793 hoarhound and tar , 1066 oxidum rubrum, 529 Hydriodic ether, 73 rose, 618 persulphas, 529 Hydro-acids, . . 532 spirit compound, 772 subsulphas flavus 530 Hydrobromate f Honeys, . 61S sulphidum rubrun 1, 531 morphine, . 122 Hope's camphor mix t. 628 Hydrargyrum, . 523 quinine, 126 Hop bitters, . . 1037 ammoniatum, . 524 Hydrobromic acid, . 201 extract, 44S cum crete, . 523 acid diluted, . 56, 59 infusion, 533 Hydrastia, "7 ether, ... 78, 79 Hoptree, fl. ext., 469 Hydrastin, 109, 11 7, 732 Hydrocarbon oil, 654 Hops, elixir, . . 333 Hydrastina, . . "7 Hydrocarbons, 532 643 fluid extract, . 462 Ilydrastine, . 117 Hydrocarbon series, 213 oil 652 colorless solution, 1129 Hydrochlorate f ointment, . 992 Hydrastis elixir, 334 berberine, . IO9 tincture, 914 and bismuth c-lixi . 335 cocaine, . . . 113 Horse brimstone, 780 elixir, ferriphos cocaine elixir, 319 chestnut bark, fl phated, . . 334 conine "5 extract, . 475 and iron elixir, 334 gelsemine, . "7 chestnut seeds, fl iron and bismuth morphine, . 105 121 extract, . . 468 elixir, 335 pilocarpine, . . 124 chestnut tincture, 946 iron and strychnin e propylamine, . 133 Horsemint, fl. ext., 469 elixir, . . 335 quinine, 126 oil 652 fluid, . . . 480 trimethylamine, . 133 Horseradish spiri . fluid ext., . 46 4, 480 Hydrochloric acid, compound, . 764 fluid ext., aqueou s, 490 . . . . 56, 60 236 oil 652 fl. ext., purified, 480 acid diluted, . 56, 6<> fluid extract, . 465 fluid ext., withou ether 73 Hoi 1 tail, fl. ext., 468 alcohol, . . 4')" Hydrocotarine, . 666 I [orsford's acid pho s- injection comp. 1087 1 [ydrocyanic acid, . 267 phate, 1023 tincture, 914 diluted, ... 56, 61 Horticultural ink, 1178 tincture compouni 1, 950 inhalation, 996 Hospital emulsion, 405 Hydrate of allyl, 134 Hydrofluoric acid, . 513 quinine, . . 129 amyl. 95 Hydrogenium, . 532 Hoi drops, 951 aluminium. 139 Hydrogen, . . 55 532 egg phosphate, 867 ammonium, 141 carburetted, 213 lemonade, . 867 barium, 18S carburetted light, 213 soda syrups, . 866 bromal, _•, « , carburetted heavy, 2 1 3 1 lound's tongue, il chloral, . . . 233 per oxide, [88 532 extract, . 474 chloral elixir, . 3M per oxide solution, 589 tongue syrup, 824 ethyl, . . . 86 per sulphide, . 7-1 11 oy t s <;<-r ma 1 1 lime, 2<«S phosphoretted, cologne, 1158 methyl, sulphide, . . . 78. Huckleberry e x t 430 nickel, . 634 sulphuretted, . 781 syrup, . . 8j 0, 857 potassium, 7(MI telluretted, . . J74 I lumulus elixir, 333 sodium, 746 Hydrosulphide of fluid extract, . 462 I [ydrated alumina, 1 19 ammonium, 149 1242 sul- sull Hydroxides, . Hyoscyamus, ext. alcoholic, Hyoscia, . . . Hyoscine, . . Hyoscina, Hyoscyamia, . Hyoscyamin, Hyoscyamine, Hyoscyamina, Hyoscyamine phas. Hyoscyamine ph'ate, . . . Hyoscyami folia, fl. extract, . radix, fl. extract, semen, fl. extract, Hyoscyamus, abst'ct, elixir fluid extract, . . juice liniment, . . . oil, seed oil, . . . s y ru P tincture, . . . Hypericum, tl. ext., Hypnotics, . . . : suppositories, Hypochlorous acid, Hypodermic tablets, compressed, Hyponitrous oxide, Hypophosphite of ammonium, calcium, . . . calcium elixir, calcium syrup, calcium and sodi- um syrup, . calcium, sodium and potas. syr., calcium, sodium, potassium and iron syrup iron, . . iron elixir, . iron syrup, iron and calcium syrup, . . iron and manga nese syrup, lime, lime syrup, lime and soda, lime and soda syr lime, soda and po tassa syrup lime, soda, po tassa and iron syrup, 467 469 462 48 335 467 775 640 6411 642 825 <)i5 47.; 098 787 236 872 &35 149 207 335 S34 835 835 835 505 336 8'36 S36 836 207 834 309 S35 835 Hypophosphite of manganese, manganese syrup potassium, sodium, . . sodium elixir, sodium syrup, Hypophosphites, compound elixir compound, glycerite, , iron, quinine and strychnine s y rup, . . . solution comp., syrup compound syrup, . syrup with iron, syrup compound Fellow's, syrup comp. with lactopeptine comp. syrup with quinine and strychnine, . Hypophosph o r o u acid, . acid diluted, oxide, . Hyposulphite of so dium, Hypo-sulphurous acid, ... Hyssop or hyssopus, fluid extract, oil syrup, . . . 615 836 707 751 336 836 675 336 1085 520 573 835 803 804 837 837 675 56, 61 674 752 78i 475 652 823 Ice camphor, camphor, with gly- cerine, camp'r, carbolat'd, glycerin. Iceland moss, fl. ext. moss syrup, . . moss comp. syr., Ice plant, fluid ext., Ignatia, abstract, elixir fluid ext., . 462 tincture, Illicium, anisatum, fluid extract, . Ilix Paraguayensis, fluid extract, . Imitation arrack, . Imperatoria fl. ext., Indelible ink, laundry ink, . • 1 103 1 146 1 146 1147 473 822 826 469 48 336 480 915 646 469 475 11SS 462 H75 "75 1174 725 489 444 459 652 893 India ink, rubber, .... Indian bael, fl. ext., cannabis extract, cannabis, fl. ext., cannabis oil, . . cannabis tincture, hemp, black, fl. ext., 468 hemp, fluid ext., . 459 hemp, tincture, . 893 hemp, white, fl. ext. , 461 liniment, . . . 1094 physic, fluid ext., 462 sarsaparilla, fl. ext., 475 sarsaparilla syrup, 803 tobacco seed, fl. ext ,462 turnip, fl. extract, 465, 487 Indigo, compound, extract, . paste, . soluble, suplate, wild, fl. ext., 461, 487 wild, tincture, Indigofera, Indigotin, Infants' and inva lids' foods, . Infusa, . . . Infusion, . . . bearberry, . . brayera, . . buchu, . calumba, . cascarilla, . catechu, chamomile, chiratre, cinchona, . cinchona, acid, cloves, . . . cusparia, digitalis, ergot, . . gentian comp hop, jaborandi, . kousso, . . linseed, . . matico, orange peel, . orange peel, comp quassia, rhatany, rhubarb, . . roses, ac'd, senega, . . . senna, . senna, comp., serpentaria;, .. 876 877 S77 877 877 877 947 876 876 1172 533 33 538 534 537 537 537 537 536 537 535 537 537 537 535, 537 537 537 538 538 534, 537 538 538 536 536 538 533 538 538 538 538 536 538 INDEX. 1243 Infusion serpentary, 53S 1 Irk, eosine, . "73 Iodide cadmium, 203 valerian, 539 eraser 1178 calcium, . . . 210 wild cherry, 535 erasing fluids, 117S calcium elixir, 330 Infusions, . . . 533 gold "77 calcium syrup, 838 general formula for , 533 green "73 chromium, . . . 239 Infusum anthemidis, 536 hektograph, . "75 gold 180 aurantii, 536 horticultural, . . 1178 iron, . . . . 506 aurantii comp. , . 536 indelible, . . . "75 iron, tasteless. 506 bray eras, 534 indelible laundry, "75 iron elix. tasteless. 337 buchu 537 India 11 74 iron, saccharated, 505 columbae. . . . 537 Japan, .... "73 iron syrup. 800 carophylli, 537 marking, . 1176 iron syr. tasteless. S39 cascarillas, . 537 marking cotton, . 1176 iron and manga- catechu, . . . 537 marking, in cakes, 1176 nese syrup, . 839 chiratae, . . . 537 maroon, "73 lead 694 cinchonas, . 535 powders, . 1176 lead plaster, . . 390 cinchona;, acidum, 537 purple, .... "73 lead ointment. 98 5 cusparias, . 537 red 1172 lime syrup, 838 cusso 537 rubber stamp, 1 176 lithium, 595 digitalis, . 53: . 537 school "73 mercury ointment, ergotas, .... 537 silver, .... "77 red 9S0 gentianas comp., . 537 stamping indelible 1176 magnesium, 602 jaborandi. . . . 538 violet 1172 manganese. 615 kramerias, . . . 538 violet-black. . . "74 manganese syrup, 839 lini 538 violet, perfumed, "73 potassium . . . 707 lupuli 538 white "77 potassium elixir. . 327 maticas, 538 yellow "73 potassium elixir, pruni Virgmianas, 535 Inks 1172 compound, . 10S7 quassias, . . . 538 copying. . . . "75 potassium 1 i n i - rhei 538 copying, colored, "75 ment with soap, 545 rosas acidum, . 538 hektograph, "75 potassium i n t - senegas, 538 ribbon, .... "77 ment, . . . 986 sennas, .... 538 sympathetic, 240, "77 silver, .... 173 sennas compositum .536 Inosit 735 sodium, 752 uvas ursi, . 538 Insect powder, . . 721 starch, .... 153 Valeriana.-, . 539 Inspissated juices, . 441 starch, soluble, 154 Inhalation of chlorine ,996 oxgall, .... 497 starch syrup, . 839 conine, .... 996 Inula Helenium.fl.ext. 469 sulphur, 780 creasote, . . . 996 extract 447 sulphur ointment. fir-wool oil. 996 oil 652 .... 992 , 989 hydrocyanic acid, 996 Inulin, .... 733 zinc, .... 1018 iodine 996 Invisible face powd., "35 Iodides, .... 540 Inhalant asthma. 1030 Iodal 96 and bromides of carbolate of iodine, 10S6 Iodamyl 151 calcium comp., 1088 excelsior, . 1086 Iodate of calcium, , . 210 tin, 773 menthol, 1086 potassium, . . . 7" Iodinal collodion, . 243 Inhalants, . . . 10S5 Iodates 540 Iodine 540 Inhalers 1085 todia 1087 carbolate given iu-, 520 Injection brou, . . 1087 Iodic anhydride, 54o carbolate inhalant, 1086 hydrastis comp., . 1087 acid, .... 54i colorless tincture, 521 rose, .... 1. .17 Iodide of ammonium 147 colorless solution, 521 Injections, !.,-(, alteratives, . . 1087 glycerite, . 521 Ink. black, . . . "73 aluminium. . . 140 inhalation, 996 black logwood, . "73 ammonium linim't, ,,„,- liniment, . . . 545 blue "73 amyl, .... 151 LugOl'S caustic sol. 538 brown "73 antimony, . 159 1^ 54o carmine, . . . 876 arsenic, 178 ointment, . 982 carmine, red, . . 246 arsenicum, . . 178 ointment, comp., . 983 carmine, true, "73 arsenic and mercu- soap 744 chromograph, "75 ry solution, 55o solution, COmp., . 559 copying, . . . "74 barium, [88 solution Lugol'fl copying, French, "74 bromine, 201 rubefacient, 588 1244 INDEX. Iodine tincture, . 915 Iron ammonium sul- Iron lactophosphate, tincture, decolorized, 950 phate, . . 503 510 solution. . . . 573 tincture, etherial, 952 ammonium tartrate . 503 lactophosphate, sy- tincture, comp., . 916 arseniate, . . . 499 rup 841 Iodized starch, . 153 beef wine of, . . 1007 malate, .... 512 cod liver oil, 399 1126 beef and cinchona manganese hypo- Iodo-bromide of cal- wine, 1008 phosphite syrup, 836 cium, comp. so- benzoate, . 5ii manganese iodide lution, . 5S3. 10S8 bitters 103S syrup, . . . 839 ferrated cod liver bitter wine of. mixture, aromatic, 623 oil, . . ._ . 1126 . . 1002, iooS, 1014 mixture, compound 623 ferrated emulsion bromide, 511 muriate tincture, . 907 cod liver oil, 400 bromide syrup, 799 nitrate, .... 512 Iodoform, 539 bromide syrup, nitrate solution, . 556 collodion, . 244 tasteless, 831 nitrogenized, . . 840 cotton, .... 539 by hydrogen, . 499 oleate 658 ointment, . 983 carbonate, . . . 5" ore, chrome, . . 702 suppositories, . . 7S9 carbonate mass, . 616 oxalate, 507 tincture, etherial, 952 chloride, 500 oxide, moist, . 507 Iodohydrargyrate of chloride solution, 554 oxide, saccharated, 512 potassium, . 712 chloride solution, oxide syrup, 801 Iodum, .... 540 (tasteless), . 57° oxides 512 Ipecac, American, chloride tincture, 907 oxychloridesol., . 557 fluid extract, 462 etherial, . . . 908 pepsin, elixir, . . 353 elixir, .... 327 tasteless, . . 570 pepsin and strych- or ipecacuanha, fl. cinchona wine, 1008 nine elixir, . 353 extract, . . . 478 citrate, .... 501 pepsin wine, . 1012 fl. ext.. aqueous, 490 citrate and ammo- perchloride solution ,555 and opium elixir. 337 nium. 502 perchloride tinct., 908 and opium powder 717 citrate elixir. . 317 per-nitrate solution 556 and opium syrup, 82S citrate of, soluble, 502 persulphate, . . 512 and opium tinct., citrate solution, . 555 persulphate solution .557 .... 917 . 950 citrate syrup, . S33 phosphate, . 508 509 powder comp., 717 conium mixture, elixir, 356 and senega, fl. ext. 483 Tully's, . . . 629 quinine elixir, . 356 syrup S05 dialysed, . 272 512 quin. and strych- wine, .... 1003 dialysed, elixir, 323 nine elixir, 357 tincture, 917 dialysed in scales, 272 solution, . 575 troches, 963 dialysed, solution, 554 syrup, . 801 844 Ipecacuanha spurge, dialysed, syrup, . 840 white, . . . 512 fluid extract, 465 ferrocyanide, . 512 plaster 385 Ipomoea jalapa, fl. ext .462 hydrated oxide, . 507 potassium tartrate, 504 Iridin, 733 hydrated oxide with powdered, . 498 Iris extract, . . . 447 magnesia, . 508 protoctrate solution 578 Irish whisky, . . 1 190 hypophosphite, 505 protoxide elixir, . 359 Irisin, 733 hypophosphite elix. ,336 iodide of calcium Iris, Florentina, fl. hypophosphite so- elixir, . 359 extract, . 362 lution, 572 iodide of potas- Florentina, tinct., 94S hypophosphite sy- sium elixir, . 360 versicolor, fl. ext. rup 836 quinine elixir, . 360 .... 464 4S7 iodide 506 quin. and strych- versicolor, tinct., 947 iodide elixir, taste- nine elixir, 360 Iron 498 less, .... 337 solution, . 578 acetate, 5" iodide, saccharated, 505 syrup, . . . 847 acetate solution, . 553 iodide, syrup. . . 800 pyrites, .... 512 acetate tincture, . 906 iodide svrup, taste- pyrophosphate, 509 albuminate, 5S6 less, '. . . . 839 elixir, 360 alum 510 iodide, tasteless, . 506 quinine elixir, 361 362 ammonio- chloride lactate, . . . 506 quinine and ar- tincture, . 949 lactate of, elixir, . 339 senic elixir, . 363 ammonium citrate, lactate, syrup, 840 quin. and strych- solution, . . .571 lacto-phosphate, . 512 nine elixir, 361 363 INDEX. 124.5 Iron pyrophosphate Isodulcit 73 s Jelly, benzin, 1 169 solution, . . . 578 Isomethyl benzene, 190 glycerin, "47 syrup, .... 847 Isonandro gutta. 725 Jersey tea. fl. ext., . 473 Quevenne's by hy- Issue plaster, 393 jockey club extract, "55 drogen, . . . 499 Itch ointment, 1 104 sachet "59 quinine citrate, 502 Ivory-black, . . . 211 Jonquil oil. 654 citrate elixir, 317 Ivy, American, fl. ext. 473 Johnswort, fl. ext., 475 citrate, solution, 555 Ivy, poison, fl. ext., Judas tree, fl. extract , 473 citrate syrup, . 834 ' 462 487 juglans cineria, fl. pepsin elixir, . 354 extract, . 465 , 4S7 phosphate syrup, 847 J extract, . . . 447 phosphorus and nigra, fl. extract., 475 strych. elixir. 358 Jaborandi, elixir, 33S regia, fl. extract, . 475 strychnine citrate 503 extract, .... 447 Juice, alterative, 1027 strychnine elixir, 357 fluid extract, . 472 beef 416 strychnine syrup, S02 infusion, 538 belladonna, 775 strychnine citrate oil 652 broom 776 elixir, . . . 318 tincture, . . . 917 chicory, . . . 776 strychnine citrate Jacaranda, caroba, dandelion, . 776 syrup, . S34 fluid extract, 475 fruit 776 strychnine hypo- Jackson's cholera hemlock, . . . 775 phosphites syr. 55- mixture, . 628 henbane, . . . 775 strychnine phos- cough mixture, . 628 juniper berries, . 775 phate syrup, . 847 cough syrup, . . 628 meat, .... 416 reduced, . 498 499 Jalapenseife, . . . 74i Juices 775 saccharated carbon. 500 Jalap, abstract, . . 48 inspissated, 442 salicylate, . 512 extract, .... 447 Julep camphor, . 1000 sodium albuminate or Jalapa fl. ext., 462 Juniper berries, ext., 775 syrup, S40 powder, compound 717 elixir, .... 338 sodium citrochlor- resin, .... 723 essence, 412 ide solution. 570 rhubarb, fl. ext., . 4S3 juice inspissated, . 775 solution, dialysed, 272 senna, fl. ext., 483 oil 648 strychnine citrate, 503 soap, .... 741 spirit, . . . . 767 strychnine citrate syrup, .... 823 spirit, compound, 768 elixir, 318 tincture, 918 syrup, .... 823 strych. citrate syr. , 834 wild, fl. ext., . . 474 tar, ... 64S 694 subcarbonate, . . 5" Jalapin 733 tar ointment, . 993 subsulphate solution, 5 57 Jamaica ginger es- tar soap, 744 succinate, . . . 512 sence, . 417, 1073 wood oil, . 64S sulphate, 509 extract, . . 417, 1073 Juniperus communis, 726 sulphate dried, 510 extract, aromatic, 1074 sulphate precipit'd, 5io fluid extract, . . 417 sulphide, . . . 512 rum, . . . . 1188 K sulpho-carbolate, rum, artificial, 11S8 .... 512 782 rum essence, . 1 1 So. Kairina "9 tannate, 512 James' powder, . 714 Kairine 110 tart rated, . 504 Japan black, . 724 elixir 333 tersulphate solution ,558 ink 1173 Kalium 699 tincture chloride, 907 lacquer, . . . 182 Kalmia, latifolia, fl. tastel* - 570 wax 216 extract, . . . 475 tonic, ... 1 1 i.j Japanese camphor, . 649 Kamala, or kamccla. tonic bitters, . . 1039 menthol, 64g 11. extra. 1. . . l'-' troches, . . . 902 Jasmine oil, . 654 tincture, M- valerianate, . . 5ii extract, triple, Us' Kaolin '." valerianate elixir, 375 yellow, tl. ext., 401 ,487 Katbarion hair tonic, I083 wine, . . 1001, IOIO yellow, tincture 909 Kava kava tl ext., 462 wine bitters, . . 1040 Jaundice bitti 1042 Keeper, cider, 1 1 S3 wire 498 Javelle's solution, KermeS, mineral, . 160 Iron wood, tl. ext , . 475 ter, . . s ( >" , 588 Kerosene oil, Isinglass 513 oniadiaphylla, Kidney leaf, ll ext., 4''- plaster 387 fluid extraet, . 175 root, tl. ext., . . 465 [sobutyl benzene, . 190 Jelly, arnica, . . . ' ' 1: liver remedies I089 1246 INDEX. Kidney and liverwort Lactophosphate ol Laundry wax, 1182 tea, .... 1092 calcium with pep- Laurel, great, fluid Killer, corn, . 1059 sin elixir, 341 extract, . 469 pain 1032 calcium with pep- mountain, fluid Kino 727 sin syrup, S41 extract, . . . 475 fluid extract, . . 495 calcium syrup, 84 1, 797 oil, expressed, 638 liquid extract, 495 iron syrup, 841 ointment, . 992 powder comp. , 717 lime elixir, . . . 340 Laurus nobilis, . 638 tincture, 918 lime syrup, . 79 7,841 fluid extract, 469 Kirkland's, cerate, . 224 magnanese syrup, 841 Lavender cologne or lotion, .... 597 Lactoph osphates water, . . . 1158 Kissengen water, compound solution, 574 essence, 413 solution, . . . 869 compound syrup 842 for perfumes, . 1152 Kola nut, fl. ext., . 469 Lactose, . 735 or lavendula, fluid Koumiss, .... 541 Lactucarium elixir, 342 extract, . 475 Kousso, fl. ext., . 459 fluid extract, . 478 oil, ...... 648 infusion, . 534 537 syrup, . . . S06 spirit, .... 768 Krameria, fl. ext., . 472 syrup Aubergier's 806 spirit compound, . 919 tincture, 919 tincture, 946 tincture, compound ,919 syrup, .... 806 Lactuca virosa, fluic Lavendula spica, 654 Ktimmel 440 extract, . 475 vera 648 essence, . . . 440 Lacquer, Japan, 182 Laville's gout mixt., 629 Lady's bedstraw, fl Laxative bitters, 1042 extract, . . . 474 Laxatives and cath- L Lady's slipper, fl. ex •, 4S7 artics, .... 1049 Laevo-glucose, 735 Laxative, child's, . 1050 Labarraque's solution 567 Lcevulose, . .51 5- 735 cathartic elixir, 313 Label mucilage, . . 1166 Lait Virginal, 1 149 cordial 1050 varnish, 1192 Lamella', . 542 elixir, . . 341, 1049 Labdanum Ointment, 993 atropine, . 542 fruit lozenges, 1052 Labrador tea, fl. ext. 469 cocaine, 542 powder, 716 Lac, ... 541 725 physostigmince, 542 tea, . . . 758, 1052 dye, . . 725 877 Lanoleum, 96S tropical fruit, . 1052 seed, .... 725 Lanolin, . . .75, 641 Laxatives, fruit, 259 stick 725 Lanthropine, 666 Lazaric Acid, 875 sulphur, . . . 779 Lapis infernalis, 174 Lead, 695 Lactate of Bismuth, 197 Lappa (root anc acetate 696 iron, .... 506 seeds), fl. extract 475 arseniate, . 698 iron elixir, . 339 Larax Americana, 730 bichromate, 698 iron and pepsin, . 339 Larch, European, 919 binoxide, . 699 iron syrup, 840 tincture, 91S bromide, 698 magnesium, 602 Lard, .... 75 carbonate, . . . 696 mercury, 532 benzoinated, . 7 6, 973 chloride, . . . 698 sodium, .... 757 oil, .... 638 chromate, . . . 698 zinc, 102 1 prepared, . 75 cyanide, . . . 699 Lactates 542 washed, . . 75 iodide, . . . . 697 Lactic Acid, . 56, 62 542 Large flowering nitrate 697 diluted, . . 56, 62 spurge, fl. extract 461 ointment, comp., 993 Lactin, .... 735 spotted spurge, fl oleate 658 Lactopeptine, 670 extract, . '487 oxide 698 bismuth elixir, 340 Larix Americana, fl oxides 699 bismuth and strych extract, . . 475 oxide semivitrous, 698 nine elixir, . 340 Europcea, . 663 plaster 389 elixir, .... 339 Larkspur seed, fluic 1 red oxide, . 699 liquid, .... 563 extract, . 461 saccharate, 699 solution, 563 oil. .... 642 subacetate glyceric - 519 syrup 842 Laudanine, 666 liniment, 545 syrup, compound, 842 Laudanum, . 925 solution, 563 Lactophosph'ate of Sydenham's, . 929 solution diluted, 564 calcium elixir, . 340 Laudanosine, 666 sugar of, 696 calcium and iron Laughing gas. . 635 sulphate, 699 elixir, 34o Laundry polish, uS2 suppositories, com , 790 1247 Lead, tannate, . . 699 water, . . . . 564. white, .... 696 Leaf cup, fl. ext., 465, 488 Leatherwood, fl. ext., 474 Leaves 22 Ledum palustre, fl. extract 469 Le Doyen's disin- fectant solution, . 5S7 Legumin, .... S4 Leg wash, Fuller's, 597 emonade hot, . . 867 .-non essence, 413, 76S ess. for perfumes. 1152 extract 413 extract, soluble, . 422 grass essence, . .1152 grass oil, . . . 652 oil 648 peel confection, . 260' peel, fluid extract, 475 phosphate syrup, 857 pop 423 salts of, ... 712 spirit 768 sugar of, . . .1194 syrup, . S07, 850, 857 syrup soda water, 423 tincture, . . . 920 yellow, . . . 69S yellow coloring, . 24S Leontodin, . . . 733 Leonurus cardiaca, fluid extract, . . 475 Leptandra elixir, . 342 extract 448 id extract, 472, 4S7 cturc, . . . 948 andrin, . . . 733 uce extract, . . 44S ' l heon, .... 79 tuce, wild, fl. ext., 475 ucoline, . . . 129 ■visticum, fl. ext., 462 latris ordoratissima, fluid extract, 475 spicata, fl. extract, 475 squarrosa, fl. ext., 475 Liebig'scorn collodion, 244 Life everlasting, fl. extract 474 T.ife root, fl. ext., 476,487 Light magnesia, . 598 Lightning, fluid, hair dye, . . .1079 tooth-ache remedy, [121 Lilac oil, .... 652 Lily of the Valley, fluid extract, . 467 extract II55 oil 65a Lily, white pond, fl. extract, . . . 469 white tablet, . .1136 yellow pond, fl. ext., 469 Lilies, cream of, . 1 133 Limatura Mart is praeparata, . . . 499 Lime, 208 chloride, . . . 209 chlorinated, . . 209 chlorinated solution, 552 essence, . . . 413 fruit phosphate syr., 858 fruit syrup, . . 858 hydrate, . . . 208 hypophosphite, . 207 hypophosphite syr., 834 iodide syrup, . . 838 lactophosphate sol., 573 lactophosphate syrup, . . 797, 841 liniment, . . . 544 phosphate, . . . 207 phosphate solution, 574 phosphate syrup, 844 saccharated solu- tion, . . 552, 79S slacked, . . . 20S solution, . . 552 sulphite, . . 210 sulphurated, . . 209 syrup, . . 798, 830 water, . . . . 551 water, stronger, . 397 Limes, juice, . . . 777 oil 649 Limette oil, . . . 652 Limonis cortex, fluid extract, .... 475 Linden, fluid extract, 476 oil, 652 Lindera, fluid extract, 462 Linimenta, . . . 543 Liniment, aconite, . 543 ammonia, . . . 543 arnica, . . . .1092 belladonna, . . 543 camphor, . . 544 crimp, ammoniated, 544 1 .miphor compound, ^44 cantharides, . . 544 chloroform, . . 544 | 1 :oi line. . . . 1093 1 roton oil, . . . 544 electric, . . . 1093 gargling oil, . . tog6 hyoscyamus, . ., 640 Indian 1094 of amnion.. It c ,7 iodide of potassium with Boap, . . 545 iodine 545 Liniment, lime, . . 544 menthol, . . . 1094 mercury, . . . 545 Mexican, . . . 1097 mustard, comp., . 545 nerve and bone, . 1097 opium, .... 545 polvform, . . . 1 194 ready oil, . . . 1097 rheumatic, . . . 109S soa P 545 Stoke's, . . . 1 129 subacetate of lead, 545 thymol-chloral, . 1094 turpentine, . . 546 turp. and acetic acid, 546 veterinary, . . . 109S volatile, . . . 543 wizard 1095 Liniments, . 543, 1092 Linimentum aconiti, 543 ammoniae, . . 543 belladome, . . 543 calcis, . . . . 544 camphora?, . . 544 camphora; ammo- niatum, . . . 544 camphora com- positum, . . 544 cantharides, 553, 544 chloroformi, . . 544 crotonis, . . . 544 hydrargyri, . . 545 lodl 545 °P». 54? plumbi subacetatis, 545 potasii iodidi cum, sapone, . . 545 saponis, . . . 545 sinapis compositum, 54? terebinthina 1 , . 546 terebinthinse acet- icum, . . . 546 Linseed, infusion, . mucilage, . . . 633 oil, . . . . . Lip salve, . 22?, [150 salves and cosmet- ics ti49 salve, coral, . . iuu Lippia Mexicana, fl. extract, . . . 4(12 Liquid acids, table, ?'> Liquidambar, . . [82 fluid extract, , . 402 syrup, ... - Liquid asphaltum, . 7.' 1 blistering, . . . bluing [178 bronzing, . . , 1179 colored fires, . . 255 osive, . 1248 INDEX. Liquid cosmetics, . 1132 depilatory, . . .1141 Dover's, . . . 950 Dutch, ... So, 83 enamel or pearl, . 1132 extract aloes, . . 493 aloes and myrrh, 494 asafetida, . . 494 Lael, .... 489 benzoin, . . . 494 benzoin comp., 494 buckthorn, . . 47S cascara sagrada, 490 catechu, . . . 495 cimicifuga, . . 460 cinchona, . . 477 coca, .... 471 dandelion, . . 479 ergot, ... 477 guaiac, . . . 495 kino 495 liquorice, . 491, 495 male fern, . . 462 malt, .... 605 myrrh, . . . 495 opium, . . 491, 496 opium deodorized, 496 Pareira, . . . 472 sarsaparilla, . 478 taraxacum, . . 479 tolu 497 paste blacking, . 11 79 polishing, . . .1182 silver polishing, . 118 1 slating,blackboard, 1178 extracts, . 453, 493 glass, .... 567 glue, . . 514, 1 165 lactopeptine, . . 563 opodildoc, . . 545 pepsin, .... 563 picra, .... 720 pitch 694 rennet, . . . .1127 rouge, . 246, 876, 1 133 shampoo, . . . 704 Liquids, coloring, . 245 fruit preserving, . 11 S3 preserving, . . 11 S3 shampoo, . . . 1144 Liquor acidi arseniosi, 547 acidi chromici, . 547 acidi phosphorici comp., 577, 753, 1023 aluminii acetici, . 547 ammonie, . . . 548 ammonia fortior, 54S ammonii acetatis, 548 acetatis fortior, 54S anisatus, . . 549 caustici, . . . 143 citratis, . . . 549 Liquor ammonii ci- tratis fortior, . 549 anodynus martiatus, 908 antimonii chloridi, 549 arsenicalis, . . 550 arsenici hydrochlo- ricus, . . . 547 arsenii et hydrar- gyri iodidi, . . 550 arsenitis potassii, 550 atropine sulphatis, 551 bismuth, . . . 551 bismuthi et ammonii citratis, . . . 551 calcii chloridi, . 551 calcis 552 calcis chlorinate, 552 calcis saccharated, 798 calcis saccharatus, 552 chlori, . . 235, 552 coloring, brown, . 245 corrosivus, . . 553 epispasticus, 243, 553 ferri acetatis, . 553 ferri acetatis fortior, 554 ferri chloridi, . . 554 ferri citratis, . . 555 ferri dialysatus, 272, 554 ferri nitratis, . . 556 ferri oxy chlorati ,554,557 ferri perchloridi, . 555 ferri perchloridi fortior, . . . 555 ferri pernitratis, . 556 ferri persulphatis, 557 ferri et quinine citratis, . . . 556 ferri subsulphatis, 557 ferri tersulphatis, 558 gutta-percha, . . 55S hydrargyri nitratis, 558 hydrargyri nitratis acidus, . . . 559 hydrargyri perchlor- idi, .... 559 iodi, 559 iodi compositus, . 559 kalii acetici, . . 560 kalii arsenicosi, . 550 kalii carbonici, . 560 kalii caustici, . . 564 Labarraque's, . 567 lithie effervescens, 560 magnesii carbonatis, 560 magnesii citratis, 561 morphinie acetatis, 561 morphinie bime- conatis, . . . 562 morphine hydro- chloratis, . . 562 morphine sulphatis, 562 natri caustici, . 566 Liquor opii citratis, 589 opii compositus, . 588 opii hydrochloricus, 589 opii sedativus, Batt- ley's 589 of opium, . . . 589 pancreo-pepsin, . 563 plumbi subacetatis, 563 plumbi subacetatis, dilutus, . . . 564 potasse, . . . 564 potasse efferves- cens 565 potassii arsenitis, 565 potassii citratis, . 565 potassii parman- ganatis, . . . 566 sode, .... 566 sodae chlorate, . 566 sode chlorinate, 566 sodii arseniatis, . 567 sodii ethylatis, . 567 sodii silicatis, . 567 strychnine, . . 568 strychnine, hydro- chloratis, . . 568 zinci chloridi, . 568 Liquores, .... 546 and cordials, . . 1192 spiritous, . . . 1187 to clarify, . . . 1 191 to filter, . . .1191 Liquorice, elixir, . 342 elixir compound, 343 extract, . . . 776 fluid ext., . . 495 liquid, . 491, 495 pure, . . . 446 purified, . . 776 syrup, . . . 825 fluid extract, . .471 fluid ext., aqueous, 491 fluid ext., comp., 483 ■ mucilage, . . . 633 powder, comp., . 716 and opium troches, 963 root, syrup, 808, S22 syrup, compound, 827 Liriodendron, fl. ext. 462 Listerine, . . . 112S Litharge 698 Litharge plaster, . 3S9 Lithia, solution effer- vescing, . . . 560 water 560 Lithic acid, . . . 994 Lithii benzoas, . . 593 bromidum, . . 593 carbonas, . . . 594 citras 594 salicylas, . . . 595 Lithium, .... 592 INDEX. 1249 Lithium benzoate, 593 Lotion, Granville's Magendie's morphine borocitrate, 595 stronger, 597 solution, . 562 bromide, 593 Gowland's, 597 tinct. of strychnine, 951 carbonate, . 594 hair, .... 1084 Magenta, . . . 154 chloride, 595 hemorrhoidal, . 597 Magic corn salve, IO60 citrate, . . . 594 Kirkland's, 597 balm, . . . IO32 citrate, effervescing, 596 moth and freckle Magnesia, . . 598 citrate, elixir, 318 • ••• 597 , 1148 and asafetidamix t. 625 diborocitrate, . 595 myrrh, . 597 calcined, 598 iodide, . . . 595 myrrh, comp., 597 calcined, heavy, 599 nitrate, 595 Palmer's, . . 598 fluid, . . . 560 oxide, . 595 pimple, . . 114S heavy, . 599 phosphate, 595 sulphur, . . "93 Henry's, 599 salicylate, . 595 Lotions, . . 596 ,1148 Husband's, 599 sulphate, 596 hair, ii43 levis, 598 Litmus, 876 Lovage, fl. ext., 462 light, . . . 598 blue, . . . 24S oil 652 milk of, 600 paper bhie, 232 Lozenges, S71 ponderosa, 599 paper red, . . 232 cathartic, . . 259 and rhubarb pow i. 719 solution, 231 compound, 872 troches, 964 Little Giant liver cough, . 106S Magnesian aperient 869 pills, . . . 1051 dyspepsia, . 1072 Magnesii carbonas, 599 Liver bitters, Ger fruit, laxative, 1052 carbonas levis, 599 man, . . 104 1 worm, . 1 1 24 carbonas ponder and kidney reme Lubricating oils, 654 osa, . . . 599 dies, . 1089 Lugol's solution, 559 citras granulatus, 600 pills, cathartic, 105 1 caustic solution f sulphas, 601 of sulphur, 701 iodine, 588 sulphis, . . 60 r Liverwort, fl. ext. , 475 rubefacient solu Magnesium, . 598 tea 1002 tion of iodine, 588 acetate, . . 602; Lobelia, fluid extract, Luminous paste, for aperient, 603, . . . 462, 472, 487 rats, etc., 1171 bromide, 602: fl. ext., acetic, 488 Lunar caustic, 147 carbonate, . ■ 599- fl. ext., comp., 483 Lung balsam, . 1067 carbonate, heavy , 599- oil 652 Lungwort, fl. ext., 476 carbonate, solutio n, 560 seed, fl. ext, . 472 Lupus metallorum, 155 chloride, . . . 602 syrup, . . . 823 Lupulin, . . . 733 citrate, . . . 602 tincture, . . 921 elixir, 343 citrate, granulate J, 600 tincture, comp., 95O fl. extract, . 460 citr. solution, 51 1 , 869 tinct., etherial, 92 I, 952 oleoresin, . 66 r citrate solution, pt sr- and capsicum, tin c- tincture, . . 921 manent, . . 561 ture, comp., 95t> Lupuline ointment, 992 iodide, . 602 vinegar, . . 53 Lycopin, . . . 733 lactate, . 602 Lobelin, . 733 Lycopus virginicus light, . , . 598 anaesthetic, 1194 fl. extract, 47 5, 4S7 oxide, 598 Locatelle's balsam, 1035 Europseus, fl. ext. 475 phosphate, . 602 t, fl. ext., . 469 sulphate, (ml iod, fl. ext., 474 M sulphate, dried, 603 extract, . . 44 7. 877 sulphite, DO] London cordial gin 119] Mace, essence, . 4' 3 tartrate, . . 603 dock gin, . . 1191 fl. extract, 46a Magnetic balm, . [032 Lotio, flava, . . oil 649 de of iron, . ni^ra, 596 syrup, . . . 858 oxide manganese 615 hydrargyri flava, 596 Maceration, . 33 Magnolia, fl. ext., 4''- hydrargyri nigra, Mac rutin, 733 Maiden hair fern, ll . . 596 Macrotys racemosa extract, . 473 Lotion anti-freckle, 1 148 11. ext, . . . 460 syrup, . . . 32a Bateman's, 579 Madder, compound 593 M.jc fern, fl. ext., l6l chilblain, . . [ODD fl, extract, . . 476 fern, oleoresin, 66] I.i' e, . . . 1 1 |- mordant, 711 Mallow, common, tl glycerin, II49 red 875 extract, . . 475 ( iranville's, milde r. 597 >!• 559 Malt 1250 INDEX. Malt bitters, . . . 6ll Malt tonic syrup, . 85S Mansa yerba, or cordial, .... 613 whisky, 1 190 herba, fl. ext., . 465 elixir, .... 344 wine 613 Manzanita, fl. ext., 469 elixir and gentian wine cordial, . 613 Maple syrup, 858 with tincture of Maltese orange syr. , 860 Map varnish, "93 iron 608 Maltine 605 Maranta, .... 153 elixirs, other, . . 344 Malting 603 Margarin, . . . 037 Malt extract, . 448, 604 Malto, 866 Marigold, fl. ext., . 468 with alteratives, . 607 syrup 866 tincture, . . . 891 beef and iron, . 607 Maltose, . . 515 , 735 Marine glue, 1165 cascara sagrada, . 611 Maltum, .... 603 soap, .... 742 citrate of iron, 608 or malt, fl. extract 475 Marjoram oil, 652 citrate of iron and Malva sylvertris, fl. wild, fl. ext., . . 469 quinine, . 6c 9 extract, . 475 sweet, fl. ext., 475 citrate of iron, qui- Manaca, .... 469 Marjorana, fl. ext., 475 nine and strych., 609 Mancona bark, fluid Marking ink, . . . 1 1 76 cod liver oil, . 607 extract, .... 465 for cotton, . . . 1176 and dialysed iron 607 Mandrake bitters, . 1042 in cakes, 1 1 76 and hypophosp., 608 elixir, .... 345 Maroon ink, . "73 and iodide of iron, 607 elixir, compound, 345 Marrubium, fl. ext., 475 and pancreatin, 607 extract 449 oil 652 and pepsin, . 607 fluid extract, . 464 syrup 823 pepsin and pan- fl. extract, comp., 484 syrup, compound, 828 creatin, 608 Manganates, . 613 ,615 Marshall's cerate, . 225 phosphates, 608 Manganese, . 613 Marsh Mallow, phosphorus, 608 acetate, 615 cream, . . . 1134 phosphorus, iron arseniate, . 615 fl. extract, . j and nux vomica,6o8 benzoate, . 615 mucilage, . dialysed iron, . 608 black oxide, . . 614 root, fluid extract hops, .... 606 carbonate, . 615 rosemary, fl. ex hyphosphites, . 609 chloride, 615 tea oil, . . 653 iodide of iron, 608 citrate, .... 615 Marunta cotr' • iron, 608 dioxide, 614 extract, lactopeptine, . 609 hypophosphite, . 615 Mary Stewart lactophosphates, . 609 hypophosphite sol. 572 fume, j liquid, .... 605 hypophosphite syr. 836 Mass blue, ,16 pepsin, .... 610 iodide, .... 615 carbonate of iron, 616 pepsin and bismuth 610 iodide syrup, . . 839 copaiba, 616 pepsin, bismuth lactophosphate sol. 574 mercury, . . . 616 and strychnine, 610 lactophosphate syr. ,841 Vallet's, . . . 616 pepsin and iron, . 610 oleate, .... 658 Massa copaibse, . 616 pep. and pacreatin, 610 oxides, .... 615 ferri carbonatis, . 616 peptones, . 610 phosphate, . 615 hydrargyri, 617 phosphate of iron, 608 phosphate solution 576 Massse, .... 616 phosphate of iron, phosphate syrup, . 844 Masses, .... 616 and quinine, 609 phosp. syr., comp. 845 Masterwort, fluid ex- phosphate of iron, sulphate, . 614 tract, . . 462 , 475 quin. and strych. 609 tartrate, 615 oil 653 phosphates, 611 Mangani sulphas, . 614 Mastic 726 tincture of iron, . 608 oxidum nigrum, . 614 spirit, compound, 772 tonic, .... 612 Manganic acid, . 615 tincture, 948 viburnium, 611 Mangifera indica, fl. varnish, "93 wafer ash, . 611 extract, . 475 Matricaria, fl. extract ,469 yerba santa, 611 Mango, fl. ext., . . 475 oil, . . . . . 653 Malt-hop phosphate Mangostana, fl. ext. 475 Matico elixir, comp.. 345 syrup, 858 Mangosteen, fl. ext. 475 fluid extract, . 467 Malt with hypophos- oil 642 fl. extract comp., 484 phites elixir, 344 Manicure powder, . 1150 infusion, 538 iron elixir, . 344 Manicure salve, . 1150 oil, 653 soothing syrup, . i"5 Manna syrup, . . 808 tincture, . . 922 948 tar cough syrup, . 612 Mannit 735 Mattenheimer's dis- tonic, .... 612 Mannitose, 515 infecting solution ,587 INDEX. 1251 Mauvine, . 155 Menthol vapor, . 996 Mercury sulphide, red . 531 May apple elixir, 345 Menyanthes, fl. ext 475 weed, fluid extract 465 fluid extract, . 464 Mercurial lotion, bl' c. 596 with chalk, . . 524 May weed, fl. extract, 475 yellow, . 596 Mesquit gum. 727 Mayer's ointment, 993 Mercurial ointment 978 Metaboric acid, . 198 McMunn's elixir of plaster, 386 Metal bell, . . . 264 opium, . 347 soap, . . . 744 cement, 1 164 Mead, . . . 423 suppositories, 789 fusible 191 excelsior, 424 Mercurialis annua, fl gun, .... 264 extract excelsior, 423 extract, . . 465 polish Il82 soluble extract, 423 Mercuric-ammoniun 1 Metals, oleates, . . 657 syrup, . . . 423 chloride, 524 Metaphosphoric acid, 674 syrup, excelsior, 424 bromide, . . 531 Methyl, . . .85 619 Meadow sweet oil, 736 chloride, . . 526 alcohol, . 85, 86, 95 Measures seidlitz, 716 cyanide, 526 benzene, . . . 190 Meat extract, 416 iodide, . 527 conine, "5 juice, . . . 416 nitrate solution, 558 hydrate, . . 95 Mecca balsam, . 1S2 oleate with morph • 659 salicilate, . . 620 648 factitious, . . 183 oleate precipitatec , 659 salts, .... 620 Meconate of morphine, 122 oxide, red, 529 Methylated spirit, . St, Meconic acid, 666 oxide, yellow, 528 Methylic alcohol, 95 Meconidina, . 122 salts, . . . 524 Methysticum, fl. ext. 462 Meconidine, . . 122, 666 sulphate, . . 529 Metz balsam, 185 Meconin, . 666 sulphate, basic, 53o Mexican liniment, . 1097 Meconoisin, . 666 Mercurious bromide . 531 Meyer's reagent for Medical discovery, 1112 chloride, 525 alkaloids, 582 Medicated globules iodide, . 527 test solution, . . 582 or pellets, . 957 salts, . . . 524 Mezereonext. etheria ,448 Medicinal pearls, 5H Mercury, . 523 Mezereum extract, . 44S soap, 742 acetate, 53i fluid extract, . 460 Medicines, propriet'\ , 1022 ammoniated, . 524 ointment, . . . 983 Melalenca cajuputi, 646 arseniate, . . 531 Micromeria, fl. ext., 462 Mel despumatum. 618 bichloride, 526 Mikania guaco, fl. ext ■ 475 boracis, . 618 binioJide, . 527 Milk 541 depuratum, 618 bromide, 53i almond, 260, 408, 114.S rosre, . . 61S carbonate, . 53i condensed, 54i Melezitose, 735 chromate, . 532 magnesia, . 600 Melilotus, or melilot chlorate, 532 punch shake, . . 865 fl. extract, 475 green iodide, . 527 punch syrup. 856 Melissa, fl. ext., 475 herb, 11. extract, 465 of roses, 1140 oil 653 lactate, . 532 shake 865 Melita, . . 618 liniment, 545 sugar, . . .541 735 Melitose, . 735 magnesia, . 525 sulphur, 77o Melon, essence or mass, 617 Mindereras spirit, . extract, . . 430 mild chloride, . 525 Mineral alkali, . 98 seed oil, . . 642 nitrate 532 drugs 17 Mcnispermin, 733 nitrate solution, 558 oils, Menhaden oil, 642 nitrate solution, ac id.ssg pitch 724 Menispermum, fl. ex . U5£ ointment, cemp., 979 turpeth, . . . 53o Menstruum, elixir oleate, . waters 868 percolating, 277 oxide, red, . 529 wax _• 1 ' . Mentha, arvensis, 649 oxide, yellow, . 523 Minium 699 piperita, fl, ext., 475 perchloride, 5 26 Mistletoe, fl. extract, 476 viridis, tl. ext., 175 perchloride sol., American, fl. ext., 475 Menthol, . . . 64a persulphate, Mistura ammoniaci, cones, . 649 phosphate, . amygdalae, . . . 621 inhalant. [08l protiodide, . . 527 asafcetidce, . ' 21 Tapani «, . . 649 ted iodide, . 527 chloroformi, . . 621 liniment, tOQ4 red Bulphide, . "li. ■ ■ . 022 ointment, . IP., Bubchloride, , 525 623 pip Bubsulphate, yello ferri el ammonii toothache cure, [iai sulphate, .... 62 ( 1252 INDEX. Mistura ferri aromatica 623 ferri composita, . 623 glycyrrhizae com- posita, . . . 624 guaiaci, . . . 625 magnesii, et asafce- tida, .... 625 oleoso-balsamica, . 628 potasii citratis, . 626 rhei et sodre, . . 626 scammonii, . . 626 senna; composita, 627 spiritus, vinigallici, 627 Mistura; 620 Mit'chella compound, "fl. extract, . . 484 fl. extract, . . . 475 syrup, compound, 828 Mithndate, . 257, 875. Mixture acetate iron and ammonium, 624 ague 1025 almond, . . . 621 ammoniac, . . . 620 anti-epiieptic, . . 628 asafetida, . . . 621 asthma, Fothergill's, 628 balsamic, Hoffm'n's, 628 Basham's, . . . 624 brown, .... 624 brown, improved, 625 camphor, Hope's, 628 carminative, Paris', 628 chalk, .... 622 chalk Richard's, . 628 chloroform, . . 621 choiera, . 1054, 1055 cholera, Jackson's, 628 cholera, Sparkman's,628 cholera, Sun, . . 629 citrate of potassium, 626 cod liver oil, with hypopnosphites, 405 cod liver oil with phosphates, . . 405 copjiDa alkaline, . 629 copiiDa, Chapman's, 629 copaiDa santal and cuDeb, . . . 629 cough, .... 1065 cough, Jackson's, 62S cough, Pancoast's, 629 creasote, . . . 622 diarrhcea, . . . 951 diarrhcea, Gould's, 629 diarrhoea, Squibb's, 629 diarrhcea, Velpean's,629 French brandy, . 627 glycyrrhiza, comp., 624 gout, Laville's, . 629 Griffith's 623 guaiacum, . . . 626 Mixture iron aromatic 623 Morphine powder, iron compound, . 623 compound, . 718 iron and conium, solution, Magendie's,562 Tully's, . . . 629 sulphate, . . . 121 mag. and asafetida, 625 sulphate solution, 562 neutral, .... 626 suppositories, . 789 potassium citrate, 626 suppositories, with rhubarb and soda, 626 soap, 790 scarnmony, 626 sy^P 843 seidlitz, .... 716 tartrate, . . . 122 senna, compound. 627 valerianate, 122 spleen, Gadberry's, 630 valerianate elixir, . 375 terebene cough, . 1067 Morphium, 119 Townsend's, . 630 Morus nigra, fl. ext., 475 Mixtures, . . . 620 Mosquito or black fly Modeling wax, . 216 preventive, . 1171 Molybdate of ammo- Moth and freckle lo- nium, 149 tion, . . 597, 1 148 Monamides, . 142 Mother tinctures, 953 Monamines, . M3 Mother's cordial, 828, 1078 Monarda fistulosa, fl. Motherwort, fl. ext., 475 extract, . 469 Mouth waters, 1 140 punctata, fl. extract 469 Mouth wat'r, salicylic 1 140 Monesia, fluid extract 468 violet 1 140 tincture, . . . 947 Mrs. Allen's hair re- Monkshood, fl. ext., 468 storer, 1083 Monobromated cam- Mucilage of acacia, 631 phor, .... 727 casein, .... 1 166 Mononitro-cellulin, . 722 of cydonium, . 631 Monotropa uniflora, dextrin, . 271, 1 166 fluid extract, 469 of elm 633 Monoxide of nitrogen, 635 of fenugreek, . . 633 Monsell's disinfect- label 1166 ing solution, 5S7 of linseed, . 633 salt 512 of liquorice, 633 solution, 557 of marsh mallow, 033 Mordants, tin, . . 774 of quince, . . . 631 Morphia 119 of salep, . . . 632 acetate, .... 120 of sassafras pith, . 632 muriate. 121 of starch, . 631 sulphate, 121 syrup acacia, . . 396 Morphina, 119 stamp, .... 1166 Morphinae acetas, . 120 tin and metal, 1 166 hydrochloras, . . 121 of tragacanthae, . 632 sulphas, 121 Mucilages, . 630, 1166 Morphine, . 119 666 Mucilagines, 630 acetate 120 Mucilago acacia. 630 acetate solution, . 56i amyli, .... 6 3 r bimeconate, 122 cyd'onii, . . . 631 bimeconate solution , 562 salep, .... 632 bromide, 122 sassafras medullar, 632 bromide syrup, 831 tragacanthae, . 632 elixir, .... 346 ulmi, .... 633 hydriodate, . . 122 Mugwort, fl. ext., . 468 hydrobromate, 122 syrup compound, 826 hydrochlorate, 121 Mulberry, fl. ext., . 475 hydrochlorate sol. , 562 syrup, 809, 850, 858 ipecac troches, 964 Mullein, fl. ext., . . 476 lozenges, 964 Muriatic acid, 56, 60, 236 meconate, . 122 diluted, . . 56, 60 nitrate, .... 122 Muriate of ammonium oleate, .... 657 elixir, 3U INDEX. 1253 Muriate of ammo- Nankeen, .... S76 Nickel oleate, 659 nium syrup, 843 Naphtha, . . . 189 671 oxides 634 iron elixir, tasteless, 314 wood, ... 95 772 plating solution, 590 iron tincture, . . 907 Naphthaline, . 694 silver, . 264 of tin solution, . 592 Naphthalin ointment, 992 sulphate, . . 634 Mutterpflaster, . . 3S6 Naples soft soap, . 743 Night blooming cere Musk cologne, . 1158 Narceia, .... 122 us extract, . 1 J 5 5 extract, .... "55 Narceine, . . .122 666 cereus, fl. ext., 46 I] 4" 7 ext. for perfumes, "53 Narcotine, . . . 666 cereus tincture. 949 oil, ... . . 654 Nasal suppositories, 789 Niker seed oil, . 642 root, elixir, 371 Natrium, .... 746 Nitrate of aconitine 104 elixir, comp. 371 aceticum, . 747 aluminium. 140 extract for perf . , "53 benzoicum, 747 ammonium, M7 fluid extract, . 462 bicarbonicum, 748 amyl, . . . 151 seed ext. for perf., 11-:} nitricum, 752 barium, . 1S8 seed tincture, . . 947 phosphoricum, 753 bismuth, x 97 tincture, Q22 413 Neatsfoot oil, . . Nectandra, fl. extract 641 . 4<'5 cadmium, . 203 Mustard essence, cerium, . 226 liniment, comp., . 545 Nectar essence or ext •,43i copper, . 265 oil, artificial, . . 134 syrup 859 iron, .... 512 expressed, . . 640 Negrosine, 155 lead, . . . 697 volatile, . . . 650 Nepeta cataria, fluid lithium, . 595 paper 229 extract, . 473 mercury, . . 532 plaster 393 Nephritic compound, 1091 mercury ointment 9S0 plasters spread, . 393 Neroli essence, . 1152 mercury ointmen spirit 771 Nerve and bone lin., 1097 diluted, . 9S1 Moulds electrotyping 161 food, " Moxie," . 866 morphine, . 122 Mountain balm oil, . 653 foods and tonics,. 866 potassium, . . ?- laurel, fl. ext.. 475 Nervensalbe, 9S7 potassium, paper 228 mint, fl. ext., . . 469 Nervine, American, sanguinarine, . 1 31 1 sage, fl. ext., . . 468 fluid extract, . 460 silver, . . . 173 Moustache wax, "45 balsam 994 diluted, . . 174 " Muxie " nerve food 866 elixir, .... 1099 fused, 174 Mycose, .... 735 ointment, . 994 mitigated, . 174 Myrbane, . . . 190 sedative elixir, 1 100 moulded, 474 oil 645 tonic [099 and potassium. 174 Myrcia acris, . . 649 Nervines 109S toughened, . 175 Myrciae, tl. ext., 462 Neroli oil, 646 sodium, 757 gale, fl. ext., . . 475 Nesbit's specific. 629 strontium, . . 774 Myrcia, spirit, . . 770 Nessler's reagant, . 583 urea, . . . 994 Myricin, . . 214 , 733 Nettle, fluid extract, 476 Nitrates, . 63 Myristioe adeps. 639 Neutral mixture. 626 Nitre Myristica, fragrans, phos. of calcium, 753 sal 708 il extract, . . . 4O2 principles, . 515 Spirit, sweet, . 7'"' Myrtle wax, . . . 215 sodium sulphite, . 755 Nitric acid. 2,636 Myrtus checan, fl. ext ,4'") spirit 88 diluted, . . Mvrrha 7?9 Neutral'g cordial, 31 1 fuming, . Myrrh, . . . 729 elixir, .... 366 anhydride, . . and capsicum tinct. 951 New England Rum, 1188 oxide, fluid extract, 495 artificial, . . . 1188 peroxide, . liquid extract, . 4<;5 New-York Sun chol- Nitrification, . lotion 597 era mixture, [05 1 Nitrite of ammoniui lotion, compound, 597 \i^ colum, 633 amyl, i = i Mil Nickel 633 amyl, pearls, . tincture, 923 acetate 634 amyl, vapor. . bromide, potassium, . 7" carbonate, , . . Nitrites, . . (, N chloride, . . . Nitrobenzol, cyanide. 634 Nitrogen, . 634 1 . . . 1 1:.. double chlorides, . acids, or manicure powd'r [I50 double sulphates, . monoxide, . or manicure salve. 1 hydrate, oxides, . • 635 1254 Nitrogen pentoxide, 635 Odors of flowers, . 1154 Oil cedrat, . . . 652 peroxide, . . . 635 (Enanthyl. . . s 5 celery, . . . . 652 trioxide, . . . 635 Oenothera bie inis.475,487 chamomile, 646 Nitrogenium, . . 634 Oil acoustic, . • • 653 chaulmoogra, . 642 Nitroglycerin, . 516, 636 allspice, ■ • 649 chenopodium, . 647 tablets 871 almond bitter, . 645 cherry laurel, . 652 Nitrogenized iron, . 840 almond expressed, 63S chickerberry, . 648 medicines, ... S4 amber, . . . 650 cinnamon, . 647 oils, 643 ambergris, . • • 654 citronella, . . 652 Nitro-hydroc h 1 r i c angelica, • • 652 cloves, , 647 acid, ... 56, 63 angleworm, . . 641 coal, .... 654 acid, diluted, . 56, 63 angostura, . . . 652 cocoanut, . . 63 S 642 Nitro-muriatic acid, 63 aniline, • 150, 154 cod liver, . . 638 acid, diluted, . . 63 animal, . . . 641 cognac, . 652 Nitroso-nitric acid, . 636 anise, . . 646 colocynth, . 640 Nitrous acid, . . . 636 apple, . . . 151 conium, . 640 anhydride, . . . 635 arnica, . . . 652 copaiba, 647 ether, . . 78, 80, 761 asa-fetida, . . 652 coriander, . 647 ether, concentrated, balm mint, . . -652 coto, . . . 652 80, 761 balsam fir, . .652, 663 cotton seed, 638 ether spirit, . . 760 bay, . . • • 649 cress, . . 652 oxide, .... 635 bayberry, . . 642 eroton, . 640 Nonyl 85 beading, . . 1190 croton liniment, 544 alcohol, .... 85 bear's, . . . 641 crude, . 671 Norwood's tincture, beechnut, . . 662 cubeb, . 647 veratrum viride, 944 behn, . . 642 cucumber seed, 642 Nuphar, ad vena, fl.ext. 469 belladonna, . . 640 cumin, . 652 Nut oils, .... 642 benne, . • • 639 curacoa, 646 Nutgall fl. ext., . . 474 benzoin, • • 654 cuscus, . . . 652 ointment 977 bergamot, . . 646 cyna, 652 opium ointment, . 977 birch, . . 652 dahlia, . 652 Nutritive soothing birch tar, . 652, 649 dead, 694 syrup, . . .1114 bitter almor ids, . 645 digitalis, 640 Nutmeg butter, . . 639 artificial, . . 190 dill 645 essence, . . 413, 770 bitter orang e, . . 646 dugong, 642 fluid extract, . . 462 black peppe r, . . 661 elder, ... 64 0, 652 oil, 649 bone, . 2ii, 641 electric, . . 1006 oil, expressed, . 639 british, . • • 653 elemi, 652 spirit, .... 770 buchu, . . • 652 ergot, 642 syrup, .... 858 burgundy p itch, . 652 erigeron, 647 Nuts, 22 cade, . . 648 etherial, 82 Nux vomica, abstract, 48 cajuput, . . 646 eucalyptus, 648 elixir, .... 346 calamus, . . 646 eulachon, . 642 extract 448 camphor, . . 652 fennel, . 648 fluid extract, . . 464 camphorate i, • • 544 feverfew, • . 652 tincture, . . . 923 Canada sna ce root, 652 fir- wood, or fir- wo 01,650 tincture etherial, . 952 candle-nut, . . 642 flaxseed, 638 Nymphssa odorata, canella, . . • 652 ■ fleabane, . . 647 fluid extract, . 469 cantharides . 640 fousel, . . 86, 9 5. 150 capsicum, . 640, 652 fusel, . . 86, 9 5. 150 caraway, • • 647 galangal, 652 caraway chz ff, . 647 gargling, . . 1096 caraway see d, . . 647 garlic, . 652 Oak poison, fl. ext., 462 carbon, . 654, 671 garlic, artificial, 134 Oak white, fl. ext., . 476 cardamom, . 642, 652 garlic, volatile, 134 Oats, common, fl.ext., 461 carrot, . . . 652 geranium rose, 652 concentrated tinct., 1129 cascarilla, . • 652 ginger, . . . 652 Obstetrical ointment, 994 cassia, . • • 647 ginger grass, . 652 Ocean spray perfume ,1155 castor, . • • 639 golden rod, 652 Octyl 85 catmint, . . 652 goose, . . . 641 alcohol, .... 35 cedar, . . . 652 green, . . . 640 Odontine toothpaste, 1138 cedarwood, . . 652 ground-nut, 662 INDEX. 1255 Oil gurjun balsam, . 652 Oil myrrh, 653 Oil spike, . . • 654 Haarlem, . 654 myrbane, . 645 spike lavender • 653 hazel nut, . 662 neatsfoot, . 641 spiritous, . • 645 hedge garlic, . 652 neroli, . 646 spruce, . . • 653 heliotrope, . 652 neroli, bigarade, 646 stillingia, . • 953 hemlock, . . . 652 neroli, petale, . 646 stone, . . ■ 655 hemp 642 neroli, petit grain 640 stramonium seed, 642 hen's, .... 641 niker seed, 642 styrax, . ■ 654 hickory nut, 662 nutmeg, 849 sulphurated, . 186 hoarhound, . . 652 nutmeg, expresse( I, 639 summer savor) , • 673 hops 652 olibanum, . 653 sunflower seed 642 horsemint, . 652 olive, . . . 639 swallows, . . 640 horseradish, 652 orange flowers. 646 sweet basil, • 653 Hungarian balsam, 652 orange peel, . 946 sweet marjoram, . 653 hyacinth, . . . 654 orange, sweet, 646 sweet sicily, • 653 hydrocarbon, . 654 origanum, . 6 5 r sweet violet, ■ 653 hyoscyamus, . 940 ,642 pear, 151 tansy, . . • 653 hyssop, .... 652 palm, . . . 642 tar, . . . ■ 649 Indian cannabis, . 652 parsley, . 653 tea, . • 653 inula, .... 652 patchouly, . 653 theobroma, . 640 jasmine, 654 peach pit, . 662 thuja, . . • 653 jonquil, .... 654 pennyroyal. 64S thyme, . . 651 juniper, .... 648 peppermint, 649 tobacco, • 653 juniper wood, . 648 petroleum, . . 654 tonka, . . . 642 juniper, empyreu- phellandrium, . 653 tuberose, . . 654 matic, 648 phosphate^, 640 tucum, . . 642 kerosene, . 654 pine apple, 201 turpentine, . 651 lard 638 pimento, . . 649 turpentine, rectified, 651 larkspur seed, . . 642 poppy, . . . 639 union salad, . 63S laurel, expressed, 638 porpoise, 642 valerian, . 651 lavender, . . . 648 pumpkin seed, 642 verbena, • 653 lavender flowers, . 648 rape seed, . 639 violet, . • 654 lemon, .... 648 rattlesnake oil, 641 virgin, . ■ 639 lemon grass, . . 652 red, .... 655 vitriol, . ■ 78] light 694 resin. . . . 723 walnut, . . 662 lilac 652 rhodium, . . 65 3. 654 walrus, . . 642 limes, .... 649 rock, 655 watchmaker's, • 639 limette or limes, . 652 rose, . . . 650 water plantain • 653 linden, .... 652 rosemary, . 650 whale, . . 651 liniment, ready, . 1097 rue 650 wild ginger, • 653 linseed, .... 638 saffron, . 653 wine, heavy, . 682 lobelia 652 sagapanum, 653 wintergreen, . 64S lovage 652 sage, . . . 653 Wood, 182, 663 lubricating, • . . 654 St. Jacob's, 1098 woodchuck, . 641 mace, .... 649 salad, . . . 639 wormseed, . • 047 mangosteen, . 642 salt, .... 236 wormwood, • 653 marjoram, . 652 santal, . 650 yarrow, . • 6g3 marrubium, . . 652 sassafras, . 650 ylang ylang, • 653 marsh tea, . 652 savin, . . . 650 zedoary, masterwort, 653 seal, .... 642 ( tiled paper, . 231 matico 653 seneka, . 954 Oils, . . . . 636 matricaria, . 653 serpentaria, 653 distilled, . • 643 meadow sweet, 736 sesamum, . 639 essential, . 642 melissa. 653 sewing machine, 641 fatty, . . fJ4 ?. 654 melon seed, 642 shark, . . . 642 fish, . . . . 641 menhaden, . . . 042 signal, . 671 . . . 637 mountain halm. 653 skunk, . 'Mi from fruit, . . 642 musk 654 smartweed, 653 hair, . . . M )1 mustard, artificial, 134 soap, methods of disl illing,643 mustard, expressed . ''1" soot, mineral, mustard volatile, , 650 spearmint, . 649 mixed, . 637. 653 mustard volatile, . 135 sperm, . . . 641 nitro) 643 1256 INDEX. Oils, nut, . . . . 642 Ointment croton oil 992 Ointment red precip- oxygenated, . 642, 643 cyanide of mercury, 992 itate, .... 9S1 paraffin, • 654 cyanide of potas. 992 resin, .... 987 from seeds, . 642 diachylon, . 976 rosemary, comp., 987 sulphurated, . ■ 643 egg. • • • 993 rose water. 971 vegetable, . . 642 Egyptian, . 993 salicylic acid, . 970 volatile, . . 642 elder flower, 992 salt rheum, . . 1 105 Ointment, . 9 63 elder, green, 992 savin 9S7 acetate of lead, • 9§4 elemi, 976 scrofularia, 992 aconitine, . • 97i emetina, 992 simple 968 alkaline, • 993 eucalyptus, 976 skin, .... 1105 alum, . . . . 962 euphorbium, 992 spermaceti, 975 ammon'd mercur y. 979 foxglove, . 992 squill 992 antiperiodic, . • 993 gallic acid, . 970 staphesacre, . . 988 aromatic, . ■ 993 garlic, . . 992 stramonium, . 988 . 994 iirseniate of iron • 992 glycerin, 977 strychnine, 992 arseniate of sodii im, 992 glycerine of sub subchloride of mer ,982 arsenical, . • 99 2 acetate of lead 978 sulphur, 988 astringent, . ■ 993 goa powder, . 975 sulphur, alkaline, 989 atropine, • 972 gold, . . 992 sulphurated potash 986 balsam of Peru, • 992 golden, . . 1 103 sulphate of zinc, . 992 basilicon, . . 2 21, 9S7 healing, 1 104 tannate of lead, . 986 basilicon, black, • 992 Hebra's, 976 tannic acid, . . 970 belladonna, • 972 hellebore, . 992 tar 984 benzoin, ■ 973 hemlock, 992 tartar emetic, . 971 benzoinated, . • 76 hops, 992 tartrated antimony 971 blue, ■ 978 iodide of lead, 9S5 tetter 1 105 boracic acid, . • "94 of potassium, 9S6 thymol 1 105 boric acid, . • 969 of sulphur, 989, 992 tobacco, 989 bromides, . • 992 iodine, . 982 turpentine, . . 990 bromine, • 992 iodine, compounc , 983 veratrine, . . . 990 brown, . • 992 iodoform, . 9S3 verdigris, . 992 ■cadmium, . • 99 2 itch 1 104 veterinary, . ii 06 caffeine, • 992 juniper tar, 993 wax 974 calamine, . • 974 laudanum, . 993 white precipitate, 979 calomel, . 9S2 laurel, . 992 wood soot, . 992 camphor, . • 992 lead, compound. 993 yel. ox. of mercurv . 9S1 cantharides, • 974 lupuline, 992 zinc, .... 991 cantharidine, . • 992 Mayer's, 993 Ointments, 9 (, 7 carbolic, . 96 9> 1 103 menthol, 1 104 and salves, 1 102 carbolic acid, . • 9 6 9 mercurial, . 978 of balsams, 992 carbonate of leac , 985 mercury, compound, 979 unofficial, . 99 * camphorated, • 9S5 mezereum, . 9S3 Old Tom gin, . . 1191 catechu, . . • 992 naphthalin, 992 Olea, 636 charcoal, ■ 992 nervine, 994 cocta 640 chalk, . . . • 992 nitrate of mercur) , 980 Europcea, . 639 chamomile, • 992 nit. of mere, diluted, 981 Oleata 655 cherry laurel, . • 992 nutgall, . 977 Oleate of aconitine, . 657 chilblain, . . 1060 nutgall and opium , 977 aluminium, 658 chloral hydrate, ■ 992 obstetrical, 994 arsenious, . . . 658 chloride of gold, • 992 oleate of zinc, . 991 atropine. 657 chloride of lead, • 992 oxide of mercury, 9S1 bismuth, 658 chlorine, . . ■ 992 oxide of zinc, . 79i cocaine, 657 chloroform, . Q92 paraffin, 984 copper 658 chrysarobin, . • 975 petrolatum, 969 iron, .... 658 citrine, . . 9S0 petroleum, . 672 lead 658 cocculus indicus, • 992 picrotoxin, . 992 manganese, . . 658 cod liver oil, . • 992 pile 1 104 mercury, 656 colocynth, . • 992 pitch, . . . 992 mercuric, precipit'c ,659 conium, . • 992 poplar buds, . 992 mercuric with mor- corrosive sublima te, 992 quinine, 992 phine, 659 creasote, • 975 red iodide of n en ., 980 morphine, . 657 INDEX. 1257 Oleate of nickel, 659 Oleum carvi, . 647 Opiate of soloman, . 875 potassium, . 657 chenopodii, 647 Opium, . . . 664 728 quinine, 657 cinnamomi, 647 alkaloids, . . . 665 silver 6 59 l cocos, .... 638 chalk powder, . 715 sodium, .... 657 copaibae. 647 confection, 256 strychnine, 657 coriandri, . 647 denarcotised. . . 665 tin 659 crotonis, . . . 640 denarcotisatum, . 665 veratrine, . .656 1 cubebse, 647 elixir 347 zinc, .... 659 erigerontis, 647 elixir, deodorized, 347 zinc, liquid, 659 eucalypti, . • . 648 extract 449 zinc, ointment, 991 fceniculi, . . . 648 extract liquid, . 491 496 Oleates 655 gaultheriae, 648 ext, liquid, deod., 40 alkaloids, . . . 6s6 gossypii seminis, . 63S fluid extract, . 496 metals 657 hedeomse, . 64S fl. extract aqueous, 49' Oleatum hydrargyri, 656 hyoscyami, 640 fl. ext., camphor'd, 496 veratrina.% \ . . 656 jecoris aselli, . 639 fl. ext., deodorized 496 Oleic acid, 56, 64.637 ,655 juniperi, 648 ipecac elixir, . 337 Olein, 637 lana;, .... 641 ipecac syrup, . 828 Oleomargarine, . 202 lauri, .... 638 ipecac tincture, 017 .950 Oleoresina aspidii, . 661 lavendulse, . . . 648 liniment, 545 capsici 661 limettse, 649 liquor, .... 539 cubeboe, 661 limonis, 648 lozenges, 9 6 5 piperis 661 lini, 638 plaster 387 lupulini, 66 1 macidis, . . . 649 powder, compound 71S zingiberis, . 661 menthie piperita, 649 powdered, . 664 Oleoresinae, . 660 mentha; viridis, . 649 saffron tincture. . 929 Oleoresin allspice, . 662 morrhuce, . 638 sol. comp., Squibb's,588 aspidium, . 66 r myrciae, . . ■ . 649 sol. sed.. Battle} 's, 5S9 Canada snake root, 662 myristicae, . . . 649 syrup S25 capsicum, . 661 myristicae expres- tincture. . . . 925 cubebs, .... 661 sum, .... 639 acetated, . . 927 ginger 661 nucistac, . . . 639 ammoniated, 927 horse chestnut, . 662 olive, .... 639 benzoated, . 928 lobelia, .... 662 papaveris, . . . 639 camphorated, . 928 lupulin, .... 661 phosphoratum, 640 compound, .951 629 male fern, . 661 pimentae, . 649 deodorized, . 929 pepper, .... 661 picis liquidae, . 649 deod. with nitre, 953 savin, .... 662 pini sylvestris, 650 vinegar, 53 < Heo-resins, . 660 rapae 639 vinegar, aromatic, 54 by U. S. P., . . ricini 639 wine, .... 1 1 N 13 water-bath percol'r , (><» > rosae, .... 650 • Opodeldoc, liquid, . 545 natural 662 rosmarini, . . . 650 1 tpoponax, 73" other, .... 662 ruta; 650 chironium, . Oleo-saccharures, 735 sabina;, .... 950 ( (range, bitter oil, . 646 Oleum adipis, 638 santali, .... 650 bitters 437 rum, . . . 82 sassafras, . 650 bitters, extract. . 437 amygdalae amarae, 645 sesami, . . . . 639 blood, syrup, . . 660 amygdalae expres- sinipis expressum, 640 chrome. 69E sum, .... 638 sinapis volatile, . 650 coloring. . . . 249 anethi 645 succini, . 650 elixir 347 .- 1 1 1 i 1 1 1 : 1 1 . • eetherium 641 terebinthihae, . elixir, COmp., 348 anisi, .... 646 terebinthin essence, . , • 4'4 anthemidis, 646 ficatus, . 651 essei aurantii corticis, . 646 theobromae, . 238 . 640 fumes, . . . aurantii tlorum, . thymi extra.!. Soluble, . 4-*4 miii, . 646 tigHi 640 flower ext., triple, [:5a puti, 646 Valerianae, . flower, oil, calami 646 < Hibanum, 730 flower, syrup, 791 camphoratum, 5+4 oil flower water. . 164 cari 647 Olive oil fruit, tincture, 888 carophylli, . 647 emulsion, . 407 ..1 Malta syrup. re< carui 647 ( Inosmodium, il. exi . r 1 peel, bitter, fl. ext. i" 1258 INDEX. Orange peel, confec- Oxide of aluminium, 139 tion 260 antimony, . 157 peel, infusion, 536 bismuth, . . . 194 peel,infusion,comp ,536 bismuth hydrated, 195 peel, sweet, fl. ext.. 473 cobalt, .... 240 peel, tinct., bitter, 887 cadmium, . 204 peel, tinct.. sweet, 888 calcium, 208 phosphate, syrup. 859 carbon 213 spirit, .... 764 iron, magnetic, 512 spirit, compound, 276 iron, red, . . . 512 sweet, oil, . . . 646 iron, saccharated, 512 syrup, . 795, 850 859 iron syrup, 801 syrup, .... 859 lead, .... 698 syrup, soda water, lithium, .... 595 .... 424 859 magnesium, 598 wine, .... 999 manganese, black, 614 Orchil 876 mercury oint., red, 981 Oregon grape, fl. ext. mercury ointment, 468 '4S7 yellow, . 981 Orellana, .... 875 mercury, red, . 529 Organic element. 210 mercury, yellow, . 528 Orgeat, essence or ex- phosphorus, 674 tract, 431 silver, .... 175 syrup, . . 794 860 strontium, . . . 774 Oriental cream, 1132 zinc, 1018 toothwash. 1136 zinc ointment, 991 Origanum, fl. ext., . 46S Oxides 667 oil 651 antimony, . 159 Orpiment, . 177 *79 barium, 18S Orthophosphoric acid carbon 213 .... 56,64 674 cerium, .... 226 Orris, essence, . . 418 chromium, . 239 extract 418 copper, .... 266 ext. for perfumes, "53 gold, .... 180 root, fl. ext., . 462 iron 512 tincture. 948 lead, 699 Osgood's Indian Chola- manganese, 615 gogue, . . . 1025 nickel, .... 634 Osmunda, fl. ext., . 475 nitrogen, . 635 Ostrya, Virginica, fl. platinum, . 695 extract, . . . 475 tellurium, . . . S74 Osmorrhiza, fl. ext., 475 tin 773 Ottawa beer. 425 uranium, 994 beer, extract, . 425 Oxycarb. of bismuth. 192 beer svrup, . 425 851 Oxychlor. of antimony -157 Otto, defined, . . 642 bismuth, . . . 197 Rose, .... 650 phosphorous, . . 674 Oxalate of ammoniun ,150 Oxydendron, fluid ex- barium 188 tract, .... 475 bismuth, 197 Oxygen, .... 666 cerium, .... 226 Oxygenated oils, 642, 643 iron, 507 Oxygenation, 667 potassium, . 712 Oxygenium, . . % . 666 silver, .... 176 Oxymel, .... 619 Oxaldines, 96 scillre, .... 619 Oxalic acid, . .57 734 of squill, 619 Ox-gall 497 Oxynarcotine, 666 inspissated, 497 Oxynitrate of bismuth ,196 prepared, . 497 Ozier green, fluid ex- purified, 497 tract, .... 474 tincture, 946 Ozokerite, . . . 216 Oxidation, 667 Ozone, .... 667 Pad copying hekto- graph, . . .1180 Pad glue 1 165 Pain cure balm, . . 1032 killer, . . 951, 1032 soothing cordial, 102S Palm oil 642 soap 742 Palmatin, . . . 637 Palmer's lotion, . . 598 Palmetic acid, . . 637 Palmetto saw berries, fl. ext., . . . 469 Panaceas or balms, . 103 c Panax, fl. ext , . . 475 Pancoast's cough mix., 629 Pancreatin, . . . 667 crystal, .... 668 elixir, . . . . 348 and pepsin elixir. 349 pepsin and bismuth elixir, . . . 349 wine, . . . .1011 Pancreatinum, . . (-67 saccharatum, . . 668 Pancro-pepsin liquor, 563 Pansy, wild, fl. ext., 476 Papaver, fl. ext., . 475 somnifer'm, 639,964,728 Papaverine, . . . 666 Papaw, fl. ext., . . 465 Paper, antimoth, . 1 170 antiasthmatic, . 230 antirheumatic, . 230 barometer, . . . 240 blistering, . . . 228 cantharides, . . 227 carbon, . . 230, 1180 copying, . . . 230 Fayard, .... 230 filtering, . . . 232 fly, 230 fly, sticky, . .1170 gout 230 litmus, blue, . . 231 litmus, red, . . 232 mustard, . . . 229 nitrate of potassium, 228 oiled 231 paraffin, . .232 parchment, . . 231 saltpetre, . . . 228 tracing 232 turmeric, ... 232 waxed, .... 232 Papers 227 test, 231 Papine, .... 1128 Paraffin, .... 216 oils, 654 INDEX. 12.59 Paraffin ointment, . 9 3 4 Pearl powder. 196 Pepsin lactic acid elix 353 paper, .... 232 Pearls, medicinal, 514 liquid 563 wax 216 of nitrate of amyl, 152 pancreatin elixir. . 349 Paraguay tea, fl.ext. 475 Peckham's balsam, . 186 powder, compound 670 Paraldehyd, . . . 97 Peckham's balsam, . 1036 ptelea elixir, . 355 elixir, .... 349 Pectoral balsam, 184 purified, . . . 669 Paramorphine, . 666 cherry, .... 1 106 quinine elixir. . . 354 Parasaccharose, . 735 drops, Bateman's, 1 106 quin. and iron elixir, 354 Parchment paper, . 231 elixir 38l quin. and strych- Paregoric, . . 893 92S pills 1107 nine elixir, . 355 concentrated, fl.ext ,496 tea, . . . 759, 1107 iron quinine and elixir 928 Pectorals, 1 106 strychnine elixir, 355 extract concent. , . 496 Peerless face powder, 1135 saccharated, . 669 rapid process for Pelargonic ether, 78 scale, .... 669 making. . 928 Pelosine, .... 107 solution, 563 Pareira, brava elixir. 350 Pelletierine, . 123 strychnine elixir, . 355 extract 449 tannate. 123 strych. and iron el. 353 fluid extract, . . 472 Pelletierina, . 123 syrup 843 tincture, 946 Pellets, medicated, . 957 wafer ash elixir, . 355 Paris' carmina t i v e Pellitory, fl. ext., . 462 wafer ash glycerite 521 mixture, . 628 tincture, 932 wine, . . 1004, ion Parsley essence, . . 414 Pennyroyal essence, 414 Pepsinum, 668 oil 653 fluid extract, . 469 saccharatum, . 669 root, fluid extract, 475 oil 64S Peptone, . 669 seed, fluid extract, 462 Pentane 213 beef 670 Parilla, yellow, fl. ext ,465 Pentasulphide of an- Peptones 670 Partridgeberry com- timony, . 160 Peptonized cod liver pound syrup, . 828 Penthorium sedoides, oil and milk, 403 fluid extract, . 475 fl. extract, 469, 487 emulsion of cod fl. extract, comp., 484 Pentoxide of nitrogen 635 liver oil, 403 Paste almond, 260 Peony, fl extract, . 469 Perchlorate of potas., 712 depilitory, . . . 1 140 Pepo, fl. ext., . . 475 Perchlorates, . 235 flour 1167 Pepper, black, fl. ex., 462 Perchloric acid, . 236 lum. for rats, etc., 1171 cayenne, or red, fl. Perchloride of antim. 549 rat 1 171 extract, . 460 iron tincture. . 908 starch 1 167 confection, . . 257 iron solutions. 555 tooth, .... 1138 oleoresin, . 661 mercury, 526 for tin 1 167 sauce, .... 1194 Percolation, . 34 Pastes 1 [67 water, fl. ext., 465. 4S 7 elixirs, requiring. 278 Pastilles, asthma. 1031 Peppermint camphor 649 water-bath, . . 40 Patchouly essence, . 1152 essence,. . .414 , 769 Percolator, water-bath, 41 extract [i 5 6 fluid extract, . 475 Percolating, econ. in 39 Oil Japanese, . 649 menstruum, elixir, 277 Patent leather dress- oil 649 Perfumed spirit. 770 ing U79 spirit 769 Perfumes for hair oil, 1 1 [2 medicines, . 1022 syrup 80S handkerchief, . [150 Paullinia (guarana), troches, . . . 964 Periodic acid, 541 fluid extract, . 464 water 169 anhydride, . 540 's bromides, 1 [01 Pepsin 6': 8 Permanganic acid, . 6i« Tea turkey, ll. ext. .468,487 and bismuth elixir, 351 oxide 615 Peach essence or ext .432 bismuth and irmi Permanganate of po- leaves, ll. ext., 473 • r: elixir, 352 tassium, . pit oil 662 bismuth, iron and Permanganates, . 615 syrup, . . 850, 860 strychnine elixir 352 Peroxide of hydrogen 5.^2 I'ear, alligator, fl. ext. .475 bis. and strych. elixir, J52 of hydrogen solut'n essence or extract. 432 compound, of nitrogen, 635 oil 151 crystal 669 Persia gratissima, fl. phosphate syrup, 86., elixir, . . .35c . 35' extract, . . . syrup, . . 850 860 elixirs, other, . Persian sherbet, Pearlash, . . 7"4 glycerite, . 521 Persimmon, fruit or Pearl barley, . 1-- ) iron elixir, . . . 353 bark. fl. ext., . . 1:1 liquid, .... 1 132 iron wine, . [OI5 Persulphate o| iron, 5'2 1260 INDEX. Persulphate of mer- Phosphate magnesiuir ,602 Physostigmine discs . 542 cury, .... 529 manganese, . . 615 salicylate,- . 123 of hydrogen, . 781 manganese syrup, 844 Phytolacca, fl. ext. Peru balsam, 181 manganese syrup. . . 469, 48 balsam, factitious, 1S4 compound, . S45 syrup, comp., . 828 balsam, reduced, 184 mercury, . . . 532 tincture, . . 948 Peruvian balsam, 181 quinine syrup, 846 Phytolaccin, . 733 beer, .... 424 quinine iron and Pickle preserving so- beer, extract, . 425 strychnine syrup, 847 lution, . . . 59i beer, syrup, 425 851 silver, .... 176 Picra 135 bitters 438 sodium, .... 753 hiera, . . . 720 bitters, extract, . 438 syrups, .... 861 liquid, . . . 720 Petrolatum, . 75, 672 Phosphates, . . . 674 Picraconitine, IOI benzoinated, . 973 elixir, compound, 356 Picrate of ammonium, 149 ointment, . 969 solution, compound .577 Picric acid, . . 57 Petroleum, 671 sol. comp. concent'c ,576 Picrotoxin, . . 675 benzin 189 syrup, compound, 845 ointment, . 992 crude, . 654 671 Phosphide of zinc, . 101S Picrotoxinum, 675 ether, . . 189 671 Phosphides, . 674 Pile ointment, . 1 104 naphtha, 189 Phosphites, . . . 675 suppositories, 790 oil, 654 Phosphorated emul- Pill bearing spurge, fl. ointment, . 672 sion cod liver oil 406 extract, . 465 refined 671 oil 640 blue, . . 616 Petroselinum, fi. ex- Phosphoretted hydro. 674 coating, . . 680 tract, . 462, 475 Phosphoric acid, di- coating, gelatine, 681 Peumus boldus, 462 luted, . . 56, 72 coating, soluble gela- Pewter, .... 156 acid, elixir, 357 cacia, 682 Phellandrium, fl. ex- acid, glacial, . 57, 65 coating, sugar, 680 tract, . 462 469 oxide 674 cough, . 1107 oil 653 Phosphorized cod driers, . 678 Phenic acid, 59, 672 694 liver oil, . . . 1126 excipients, . 677 nascent, syrup, 844 Phosphorol, . . . 1126 making, 678 Pheno-salicylic acid, 737 Phosphorous acid, . 675 making conv'ni'nces,677 Phenol, . 59, 672 694 Phosphorus, . 673 Pills 675 propyl, alcohol, . 713 acids of, ... 674 ague and neuralgic , 1025 pthalein, 672 allotropic forms of, 674 cathartic, liver, 1 05 1 sodique, 587 amorphous, 674 compressed, 872 Phenyl, .... 672 black 674 female, 1079 hydride, 189 chloride, . . . 674 formula;, . 683 to 693 propyl cinnamate. 1S2 elixir, .... 358 Holloway's, . 1127 Phenylamine, 150,15. ,673 elixir, compound, 358 little giant, 1051 Phenylate of ammo- etherate, 82 little liver, . . 1051 nium, 150 glycerite, . 521 pectoral, 1107 Philonium Romanum 875 hydride, 674 plast'rs and p'wd'rs, 1 107 Phoradendron, fl. ext. 475 iron quinine and Plummer's, 159 Phosphate, acid, 577, 1023 strychnine elixir, 35S silvering and gilding, 682 aluminium, T40 liquid, .... 674 Pilocarpina, . . 124 ammonium, . . 147 nu\ vomica elixir. 358 Pilocarpine, hydro calcium acid, . 755 oxides, .... 674 chloras, . 124 calcium elixir, 356 oxy chloride, 674 Pilocarpine, . 12a calcium precipitatec ,207 red 674 hydrochlorate, 124 calcium neutral, . 755 solution, compound 590 Pilocarpus elixir, 338 calcium syrup, S44 sol., Thompson's, 589 fl. extract, . . 472 iron, . . 508 509 tincture, compound 951 tincture, 917 iron elixir, . . . 356 white, .... 674 Pilulre, , . . 675 iron and quin. elixir, 356 Physic, Indian, fl. ext ,462 copaibce, 616 iron and quin. syr. 847 Physostigma, ext., . 449 Pilulie ferri carb., 616 iron syrup, . . 801 S44 fluid extract, . . 462 ferri carbonici, 617 iron, white, 512 Physostigmina, . 123 Pimento, fl. extract 462 lime, precipitated, 207 Physostigmince sali- water, . 170 lime syrup, S44 cylas, 123 essence, . . 414 lithium, 595 Physostigmine, . 123 oil 649 INDEX. 1261 Pimpernel or pimpi- antimonial, 392 Platinum 695 nella, fl. extract, 462 belladonna, 3S4 black 695 scarlet, fl. extract, 473 black, . . . 386 chloride, . . . 695 Pimpinel tincture. . 931 blister, . . . 219 oxides 695 Pimpinella anisum, . 646 burgundy pitch, 3SS sponge, .... 695 Pimple lotion. 114S calcined, 210 spongy, .... 695 Pinchbeck, 294 camphor, . . 392 Pleurisy root, fluid Pineapple, ess. or ext .432 Canada pitch, 3S8 extract, . . 46 r . 4S7 oil 20 1 cancer, . 392 Plum, essence or ext. , 432 phosphate syrup. S61 cantharides, 2 9.384 syrup, . . . S50, 861 syrup, . . .850 861 Capauchin, 393 Plumbi acetas, . 696 Pine tar 694 capsicum, . . 334 carbonas, . 696 white, fl. extract, 475 chalybeate, 3S5 iodidum, . . . 697 Pinit 735 corn, iofio nitras, .... 697 Pink root elix., comp .359 court . . . 3S7 oxidum, 69S fluid extract, . . 472 croton oil, . . 393 Plumbum, . . . 695 and Senna, fl. ext. 484 dentists', . . 210 Plummer's pills,. J 59 saucers, 876 diachylon, . 389 Podophyllin, . . 723 , 733 Pinus Australis, . 662 elemi, 393 Podophyllum, abstract, 4S Canadensis ext., . 1074 euphorbium, . 393 elixir, .... 345 Canadensis, fl. ext. .476 galbanum, . 386 elixir compound, . 345 pumilia, 663 ginger, . . . 393 extract, .... 449 strobus, fl. extract, 475 hemlock pitch, 388 fluid extract, . . 464 sylvestris, . . . 650 iodide of lead, 390 tincture, . . . 932 Piper, methvsticum, iron, 385 Poenia officinalis, fl. fluid extract, 462 isinglass, 3S7 extract, . 469 nigrum, fluid ext., 462 issue, 393 Poison bug, . 1 1 70 rip-menthol. . . . 649 lead, 3S9 oak or ivy, fluid Pipsissewa, fl. extract ,471 lead compound, 39° extract, . . 462 ,467 syrup 824 litharge, 389 oak tincture, . . 947 Piscidia, fl. extract. 469 mercurial, . 3S6 rat, "71 Pistacia terebinthus, 663 mustard, . . 393 rat paste, . 1171 lentiscus, . . . 726 mustard, spread, 393 Poke root fl. ext. ,469, 4S Pitch 694 opium, . 337 root, fl. ext., comp. ,484 black 694 of Paris, 210 syrup, compound, 828 burgundy, . . . 694 pitch, 3S8 tincture. 94S Canada, 694 pitch, with cantha r- Polemonium reptans, cerate 225 ides, . 389 fluid extract, . 4") hemlock, 694 poor man's, , 393 Polish for brass or mineral. 724 quinine, 393 metal, . . . 11S2 ointment, . 992 resin, 390 glass, .... 11S1 plaster 388 simple, . 394 furniture, . 11S1 plaster with canth., 389 soap, . . . 391 harness, white pine, . 694 soap, brown, . 391 laundry, 1182 Pitcher plant, fl. ext. 47'' sticking, 393 silver, .... 1181 Pix 694 strengthening, 385 stove, .... 1 [82 burgundica, 694 universal, . 385 tin II -J < Canadensis, . . 694 verdigris, . . 394 Polisher's putty. 774 liquida 694 warming, . . 389 Polishing liquid, [1 82 Plantain, common, wax. 394 powder silver, 1 181 fluid extract, 476 white lead, preparations, . . 11S0 Plantation bitters, . 1038 zinc lead, . 394 putty, .... [ 1 82 Plantigo, major, fluid Plasters, . . . 382 Polj i' 'i in liniment, . [I94 extract, . 476 ext rail, Polygala amara, fluid Plant food, . 1172 Plate liquor, . . 590 extract., . 475 476 Plants 21 Plating solution, go .1, 590 bitter, il. extract, 4 7" Plaster, aconite, 392 nickel, Polygonatum gigan- adhesive, . 390 silver, . . 59° tenm, il. ext . 469 ammoniac, . . 382 solutions, . 590 Polygonum, fluid amnion, with nut,, Platinic chloride, extrat t , . . 405 487 arnica 383 Platini chloridum, Polymnia uvadelia, asafetida, . 383 Platinous oxide, , fluid extract, 465 467 1202 INDEX. Polypodium or poly- Potassii hypophosphis . 7°° Potassium sulphide, 712 pody, tl. extract, 476 iodidum, 707 sulphite, 709 Polytrichum. fl. ext., 476 nitras 708 sulphite, neutral, 7cg Pomade, barber's, . 1 144 permanganas,. 708 sulphocarbolate, 7S2 d'or, .... 992 et sodii tartras, 706 747 sulphocarbonate, 712 hair grower, . "43 sulphas, 709 sulphocyanate, 712 Hongroise, 1145 sulphis, .... 709 tartrate, 710 pour le toucher, . 994 tartras 710 tartrate, neutral, 710 pultz 1182 tartras acida, . . 703 Potencies, 953 Pomades, flower, 645 Potassio-ferric tart., 504 Potentiation, . . 953 flower 76 Potassium, 699 Potentilla, tormen No. 24 and 30, 76 acetate, .... 701 tilla. fl. extract 469 Pomades, .... "44 acetate solution, . 560 Canadensis, fl. ext., 469 stick, .... "45 acid tartrate, . 703 Poultry powder, . 1058 Pomegranate decoc'n 270 antimoniate, . 710 Powder of acacia fluid extract. . 474 antimoniate acid, . 7" compound, . 717 Pond lily, white, fl. arseniate, . 711 algaroth, . . 159 extract, . 469 arseniate solution, 565 almond, compound, 714 yellow, fl. ext., 469 arsenite solution, 550 aloes and canella, 720 Toor man's bitters, . 1042 bicarbonate, 701 aloes, compound 720 man's plaster. . . 393 bichromate, 702 aloes and iron, 720 Pop, lemon, . 423 binoxalate, 712 antimonial, ■ . 7M sarsaparilla, 424 bisulphate, 711 aromatic, . 714 Poplar buds ointment .992 bisulphite, . . . 711 bandoline, . "31 white, fl. extract, 479 bitartrate, . 703 baking, . 1167 Poppy extract, . 449 borate, .... 7" bitters, . . . 1043 fluid extract, . 475 borotartrate, . . 711 calomel and jalap 720 oil, 639 bromide, 703 catechu, compound, 715 red, fluid extract, 476 bromide syrup, 333 chalk, aromatic, 715 syrup, red. 813 carbonate, . 704 chalk, compound 715 Populin 733 chromate, . 711 chalk and opium Populus albus, fl. ext ,469 chromate, red, 702 aromatic. 7i5 candicans, fluid chlorate, . . . 704 cinnamon, comp. 7M extract, . . 462 487 chloride, . . . 7" composition, . 720 Porpoise oil, . 642 citrate, . , . . 705 cubebs and alum 720 Port wine, 997 citrate solution, 565 ,57i curry, "94 Pot pouri sachet, 1 160 cyanate, 711 depilatory, . . 1141 pouri for rose jars, 1 160 cyanide, 705 diapente, . . 721 Potash, ... 97 700 cyanide elixir, 321 Dover's, 717 caustic 700 ferricyanide, . 7" effervescing, . 713 sol'n, effervescing, 565 ferrocyanide, . 706 elaterin, compound, 716 water, .... 565 hydrate, 700 fumigating, 721 yellow prussiate, . 706 hypophosphite, . 707 glycyrrhiza, comp ., 7i6 Potassa, .... 700 iodate, .... 7" Gregory's, . . 718 alkali, .... 97 iodide, .... 707 heave, . . . 1057 alum, .... 137 elixir, 337 hog cholera, 1057 caustic 700 iodide liniment with insect or fly, . 721 cum calce, . 700 soap, .... 545 ipecacuanha, comp., 717 with lime, . 700 iodohydrargyrate , 712 ipecac and opium 717 soap, .... 741 nitrate 708 of jalap, comp., 717 solution, . . . 564 nitrite, .... 712 James', . 714 sulphurata, . . 701 oleate 657 kino, compound, 717 Potassii, acetas, . 701 oleate solution, 657 laxative, 716 bicarbonas, 701 oxalate, 712 liquorice, compou id, 716 bichromas, . 702 perchlorate. 712 magnesia and rhub.,719 bitartras, . . . 703 permanganate, 708 manicure, . 1 1 50 bromidum, . 703 permanganate, sol. 566 morphine, comp.. 718 carbonas, . 704 quadroxalate, . 712 opium, compounc , 718 chloras, .... 704 salicylate, . 712 pearl, . . . 196 citras 705 silicate 712 pepsin, compound, 670 cyanidum, '. . . 705 and sodium tartrate » 706 poultry, 1058 ferrocyanidum, 706 sulphate, 709 rhubarb, comp., 718 1263 Powder of rhubarb and magnesia, . 719 salicylic acid and talc 719 scammony, comp., 719 tragacanth, comp., 719 Tally's, ... 718 worm 721 worm, for horses, etc 105S Powdered extracts, . 441 iron 498 Powders, . . . . 713 complexion, . .1135 compound, . . 872 condition, . . . 1055 eclectic, . . . 731 effervesc, aperient, 715 face and toilet, . 1135 fineness of, . . 31 hair 1146 ink 1176 sachet n 59 seidlitz, . . . 715 soda, .... 714 tooth 1138 Precipitate, red, . 529 white 524 Precipitates, washing, 44 Preparations, adhe- sive, . . .1163 toilet, . . . .1131 hair, . . .1149 Prepared corks, . . 1193 flavoring, . .227 lard 75 ox-gall 497 wine 1006 irative cider, . 1183 fruit juice, . . . 1183 Preservatives, . . 1 183 "83 Preserving organic substances, . .1184 solution, Wickers- heims, . . . 1 184 miens, . . 1 184 Pressure process, . 457 'rest. »u's salts, . . 1 160 'reventive mosquito, etc., . . . .1171 rickly-ash bark, fl, extract, . . . 460 berries, fl, ext., 402 southern, ll ext., 473 leof India, fl, ext., 461 Primrose, evening, fl, 474, 487 Prinos, ilui«l extract, 476 Pun' >■ Rupert's metal, 264 I is for fluid exts., 455 pressure, . 457 Process for repercola- tion 456 U. S. 1S70, . 455 U. S. 18S0, . 455 water-bath perco- lation. . . . 45S Processes, working, 24 Products, chemical, 19, 23 pharmaceutical, . 23 Propane, . . . . 213 Prophylactic fluid, Darby's, . . . 587 Propenyl 516 alcohol, . . . 516 tristearate, . . . 516 Proprietary medicine, 1022 Propyl, ... 85, 713 alcohol, .... 85 Propylamine, 132, 713 chloride elixir, . 359 elixir, .... 359 hydrochlorate, . 133 salicylate elixir, . 367 Propylbenzene, . . 190 Propylenyl, . . . 134 Propylic alcohol, . 713 Protein compounds, 84 Protiodide of mercury, 527 tin, .... . 773 Protoxide of iron elixir, 3 5 9 iron solution, . . 578 iron syrup, . . S47 Prune, essence or ext.. 433 Trunin, .... 733 Prune syrup, . . 850, 861 Prunus Virginius, fl. extract, . . . 478 Prussian blue, . . 512 Prussiate of potash, 706 j l'russic acid, . 61, 267 Pseud-aconine, . . 101 Pseud-aconitine, . IOI Ptelein, . . . 732, 733 Ptelea trifoliata, fluid ext., 469, 4S7 Pterocarpus marsup'm,727 Ptyalin 604 I'ullna water solution, 870 Pulmonaria, fl. ext., 476 Pulmonary syrup, . 82S Pulsatilla, 11. extract, 469 tincture, . . . 947 Pultz pomade, . . 11S2 71 2 ellerves, elites, . 714 Pulvis aerophorus, . 713 Anglicus, . . 714 laxans, . . 716 aloes et eailell.e, . 72(1 amygdalae comp's, 714 antimonialis, . . 714 aromaticus, . . 714 Pulvis catechu com- positus 715 cinnamomi comp's, 714 creta; aromaticus cum opio, . . 715 creta? compositus, 715 effervescens comp's, 715 elaterini comp's, . 716 glycyrrhiza? comp's, 716 gummosus, . . 717 ipecacuanha? comp's, 7 1 7 ipecacuanha? etopii, 717 ipecacuanha? opi's, 717 jalapa? compositus, 7 1 7 kino compositus, . 717 liquirita? compositus, 716 morphime comp's, 71S opii compositus, . 718 rhei compositus, . 71S salicylicus cum talco 7 19 scammonii comp's, 719 tragacantha?, com- positus, . . . 719 Pumpkin seed, fl. ext., 477 seed oil, . . . 642 Pungent smell'g salts, 1 160 Punicine, .... 123 Purgative suppos's, 790 Purifier, blood, . . 1044 Purified sulphide of antimony, . . 158 ox-gall, ... 497 Purifying beeswax, 1193 Purple ink, . . 1 173 Putt\-, polishers', . 774 polishing, . . . 1182 Pyenanthemum, 11. extract, . . . 469 Pyrethrum, fl. ext., 462 parthenum, fl. ext., 476 roseum, . . . 721 tincture, . . . 932 Pyridina, . . 124 Pyridine, . . .124, 133 Pyrmont, water solu- tion 870 Pyroacetic spirit, 77a Pyroboric acid, . . 19S llicacid, . 57, 873 Prola rotundifolia, fl. extract, . . 470 Pyrophosphate oi iron, 569 iron elixir, . . . 360 iron solution, . . 578 in >n syrup, - 17 sodium, . . . 754 Pyropbosphoric add, 67 \ Pyroxylic spirit, . 772 I lin, . . . 721 linura, 721 Pyrus Mains, fluid ex- tract 47'") 1264 INDEX. Q iron, pepsin and Red cherry ess. or ext. ,434 strychnine elixir, 355 chrome, 698 Quadroxalate of potas- iron phosp. syrup, 847 cloverheads, fl. ext., 476 sium, . . . 712 iron and strychnine cochineal, . 246 Qualitative test solu., 579 phosphate syrup 847 cudbear, . . 247 Quantitative test solu. 584 morphine brom.syr ,832 currant ess. or ext., 434 Quassia extract, . . 449 morph. and strych- elixir, 367 fluid extract, . 472 nine brom. syr., 832 fruit, cochineal, 247 infusion, 533 muriate, 126 gum, tincture, 948 tincture, 932 ointment, . 992 iodide of mercury , 527 Quebracho fl. ext., . 465 oleate, .... 657 lead, . . . 699 tincture, 947 pepsin elixir, . 354 madder, . . 875 Queen of the Meadow pepsin and strych- mercuric oxide, 529 fl. extract, . . 474 nine elixir, . 354 oil 655 Queensroot, fl. ext.. 472 phosphate elixir, . 364 oxide of mercury 529 syrup compound, . 829 phosphate syrup, . 846 phosphorus, . 674 Quercit, .... 735 plaster, .... 393 poppy syrup, . 3i3 Quercitrose, . 735 strychnine glycerite . 5 22 precipitate, 529 Quercus alba, fluid sulphate, 127 precipitate oint't 9S1 extract, . 476 sweet, .... 129 root, compound syr. ,827 Quevenne's iron by- tincture, 933 root, fluid extract 478 hydrogen, . 499 tinct. ammoniated, 933 saunders, fl. ext. 462 Quicksilver, . 523 valerianate, 129 or scarlet, . 252 Quieting syrup, . . 1114 valerianate elixir, 375 sulphide of mercury, 531 Quillaia fl. ext., . . 469 wine, .... 1004 Turkey, 875 Quillaya, sea foam, 1 144 Quinoidin, . . . in Venetian, . 512 tincture, 948 Quinolina, 129 wine, . . . 1005 Quince, bandoline, 1131 Quinoline, 129 wine artificial, 1186 Bengal, fl. ext., . 489 wines, . 1185 essence or ext., 433 Reduced iron, . 498, 499 mucilage, . 631 R iron lozenges, 962 syrup, . . 850 862 Regulator, heart, 1085 Quinine tooth powd. , 1139 Rackasira balsam, . 182 Regulus, . 155 Quinia 125 Rademacher's tinct. Relief, ready, 1033 , 1094 sulphate, 127 acetate of copper .94S Remedy, ague, . 1024 Qumicine, in tinct. acetate of iron, 907 cough, . 1061 Quinidia, .... I2 5 Ragweed, fl. extract, 473 digestive, dyspep , 1072 sulphate, 125 Rape seed oil, 639 dyspepsia, . . 107 1 Quinidina, 125 Raspberry ess. or ext -433 kidney and liver, 1089 Quinidince sulphas, . 125 juice 777 Remedies, cough, 1061 Quinidine, 125 leaves, fl. extract, 476 catarrh, , . 1047 sulphate, 125 phosphate syrup, . 862 diarrhoea, . 1068 Quinina, .... 125 syrup, . . .815 862 dysentery, . 1068 Quininse bisulphas, . 126 syrup, black, . 850 female, . . . 1076 hydrobromas. . 126 syrup, red, 850 rheumatic, . 1 108 hydrochloras, . 126 Rat paste, 1171 standard, . 1022 sulphas, . . . 127 poison 1171 toothache, . . 1120 valerianas, . . . 129 Ratsbane, .... 177 Renewer, hair, . 1081 Quinine, .... 125 Rattlesnake oil, . 641 Rennet, liquid, . 1127 bisulphate, . 126 Ready balm, . 1033 Renovator, tonic, sys ,1040 bisulphate elixir, . 364 oil liniment, . . 1097 Repercolation process, 456 bromide, 126 relief, . . 1033, 1094 Resin 662, 722 bromide syrup, . 831 Reagent, Meyer's, . 582 cerate, . 221 bush, fl. extract, . 469 Meyer's, for alka- cerate, compound 222 elixir 363 loids, .... 582 of copaiba, 723 flower, fl. extract, 476 Nessler's, . 533 demar, . 723 glycerite, . 521 Realgar, . . .177 179 of jalap, 725 hospital, . . . 129 Recipes for coloring, 877 oil, .... 723 hydrobromate, 126 Rectal suppositories, 784 ointment, . 987 hydrochlorate, 126 Rectified spirit, 87 plaster, . 390 iron citrate, 502 Red bark. fl. extract. 477 of podophyllum, 723 iron and pep. elixir 354 carmine, . . 246 scammony, 724 INDEX. 1265 Resina 722 | Rhubarb soda mixture, 626 soothing syrup, . 11 14 syrup, . . . . 812 syrup, aromatic, . 813 syrup, spiced, . 813 tincture, . . . 934 aqueous, . . 934 aromatic, . . 935 compound, . . 951 spiced, . . . 935 sweet, . . . 935 vinous, . . . 936 wine of, ... 1005 Rhus aromatica, fl. extract, . . 469, 4S7 glabra, fl. extract, 472 toxicodendron, fl. extract, . . 462, 487 toxicodendron tinct. ,947 copaibje, 723 damar, .... 723 draconis, . . . 72s elastica, 725 jalapoe 723 podophylli, . . 723 scammonn, 724 Resinte 722 Resinoids, . . . 731 general formula for 73i Resinous substances, 722 Resins, .... 722 Resolvent sarsap'a, . 1112 Resorcin 728 Restoratives, hair, . 1081 Restorative wine bit- ters, .... 1014 women's health, . 1077 Rex magnus specific, 1117 Rhamnus catharticus, fluid extract, . 476 frangula, fl. ext., 477 prushiana, fluid extract, 473, 476 490 Rhatany extract, 44« fluid extract, . 472 infusion, . . . S38 syrup 806 tincture, 919 troches, 03 Rhein 733 Rheum, fluid ext., . 476 Rheumatic bitters, . 1 109 elixir 1 109 liniment, 1098 remedies, . 1 108 tea mo Rhigolene, . . 671 Rhodium oil, .653 , 6*1 Rhododendron maxi- mum, fl. extract, 469 tincture, 946 Rhoeadine, . . . 666 Rho as, fl. extract, . 476 Rhubarb, aromatic, fluid extract, 4S4 COlumbo elixir, 36«5 and iron elixir, . 3<>5 dandelion, fl. ext., 482 elixir 3 r >5 extract 450 extract compound, 450 fluid extract, . 467 infusion, . . . S38 and jalap, fl. ext., 483 magnesia elixir, . 366 potassium elixir, . 366 potassium Byrup, . 829 powder, compound 718 senna fluid ext., . 484 senna tincture, Rhusin Ribbon inks, . . Rice Richards' chalk mixt Rich weed, fl. ext., . Ricinus communis, . leaves, fl. ext., . seeds, fl. ext., tincture, . . . Riga balsam, . Robina, fl. extract, . Roborans elixir, . Roccella tinctoria, . Rochelle salt: Rock candy, syrup, oil, . . rose, fl. extract and rye, rye and tolu Root beer, beer extract, beer syrup, Knots, . . . Rosa Uamascena Rosaniline, . Roseine, . Rose, bandoline, bloom of, . cerate, . confection, essence extract, triple, fluid extract, . . geranium, essence hair lotion, . . honey injection, . jars, pot pOUli, . oil or otto. . . . red syrup, . . . sachet 733 [177 153 62S 473 639 476 462 948 182 469 902 . 876 706, 747 • 734 . 848 • 655 • 475 . 1 190 . 1 190 • 427 • 427 427,851 syrup, 650 154 154 1131 "33 225 257 414, 1152 1 152 472 1152 • "43 . 618 . I I (Ml . 86a .11, Rose tincture, toilet powder, tooth powder, wash, water, . water ointment Roses, milk of, cream, . infusion, acid, Rosemary, essence, .... 415, marsh, fl. ext., oil ointment, comp., spirit, ... tincture, Rosin weed, fl. ext., Rottlera, fl. ext., tincture, Rouge, . . .51 246, 948 1136 "39 1087 170 97i "49 1132 53S 1152 476 650 987 77i 64S 462 462 94S 2,876 liquid, . 240, 1 1 33 pure 876 vinegar, . . .1133 Rubber, cement, . 1 164 hard 725 India, .... 725 stamp ink, . . .1176 tire cement, . .1164 vulcanized, . . 725 Rubia, fl. extract, . 47<> tinctorum, . . -75 Rubus, strigosus, fl. extract, . . . 476 syrup, . . . S14, 823 villosus, fl. extract, 467 Ruby sulphur, . . 177 Rudbeckia, fl. ext., 476 Rue, fluid extract, . 471. oil 650 Rum, artificial, . . . Il88 bay, . . . 770. ii.|( essence Jamaica, . 1189 Jamaica", . . . Il88 New England, . 1188 Santa Cruz, . u -- St. Croix, . . [188 Rumex, fl. extract, , 47a fl. ext., comp., sj rup, compound, 829 Rumirj 733 Rush, scouring, fl. extract. . . . 40S Russian chol'a drops, [054 Rut. 1 graveolens, graveolens, fl. ext Rye and rOCk, rOCk and tolu, smut or spurred fluid extra* t, whisky, . whislq 476 tigo 477 1 ! -■> I I9Q 1266 INDEX. s Sal tartar, • 704 Salts tartar, . . . 704 volatile, • 145 Salve, camp, cream, 1047 Sabadilla, fluid ext. 462 Salep mucilage, • 632 carbolic, . 970, 1 103 Sabbatia annularis Salicin, . . • 736 corn, . . 1059, 1060 fluid extract, 476 elixir, • 367 catarrh, 1048 Elliottii, fl. extract, 476 Salicinum, • 736 lip, . . . 225, 1 1 50 Sabina, fluid extract , 460 Salicyl, • 736 manicure, . 1150 Sabal serrulata, fl. ej .t. 469 hydride, • 736 sticking, . . . 393 Sacchara, . . 733 Salicylates, • 737 Salves, eye, . . , 1075 Saccharate of lead, 699 Salicylate of ammo- and ointments, 1 102 Saccharated carbon nium, . 150 Salvia, fluid extract, 476 ate of iron, . 500 bismuth, . 197 Sambucus, fl. extract , 476 ferrous iodide, 505 eserine, . 123 Sandarach, 726 iodide of iron, 505 lithium, • 595 Sanguinaria, fl. ext., 460 pancreatin, 668 methyl, 620, 648 fl. extract, acetic. 488 pepsin, . 669 physostigmine . 123 syrup, .... 823 sol. of lime, . 55 2, 798 potassium, . . 712 tincture, . . . 937 spermaceti, 227 sodium, • 754 vinegar, . . . 54 Saccharates, . 735 sodium elixir, . 667 Sanguinarin, . 733 Saccharine, . 735 sodium solution, . 591 Sanguinarina, 130 substances, 735 zinc, . 1021 Sanguinarine, 130 Saccharoids, . . 733 Salicylic acid, 57. 736 nitrate 130 Saccharose, . 735 acid elixir, . • 368 sulphate, .' . 130 Saccharum, . . 734 acid ointment, • 97o Sanguis draconis, 725 lactis, . . . 542 acid and talc powd., 719 Santa Cruz rum, 118S Sachet ess. bouquet , "59 aldehyd, . 96 Crux rum artificial 1188 frangipanni, . 1159 mouth water, . 1 140 St. Croix rum, . 1188 general, base for "59 tooth ache cure, . 11 21 Santal ext. for perf., "53 heliotrope, . "59 Salicylica, rheumatic essence, "53 jockey club, "59 remedy, . . 1 108 oil, 650 pot pouri, . 1 1 60 Salicylol, . • 737 white or yellow, fl. powders, "59 Salicylous, acid, • 737 extract, . . . 462 rose, .... "59 Saligenin. . • 736 Santalum citrinum, violet, . "59 Saline fruit, . . 1116 fluid extract, 462 ylang ylang, . "59 Salix, . . . • 736 rubrum, fl. extract 462 Satflower, fl. extract 473 alba, fl. ext.. • 469 Santonica, 737 Saffron, American nigra, fl. ext., • 469 fluid extract, . . 462 fluid extract, 473 Salol, . . . • 737 Santonin, . . . . 737 foreign, . . . 904 rheumatic remedy, 1109 elixir, . . . . 36S oil, .... 653 Salt, . . . • 75o lozenges, . . . 965 syrup, . . . 824 celery, . • "94 Santoninate of sod'm . 753 tincture, 904 Epsom, . . 601 Santoninum, . 737 true, fluid extract 474 fruit, . . . 1116 Sapoes, . . . . 733 Safrene 650 Glauber's, . • 755 Sapo 740 Safrol, .... 650 grape, . . . 1116 animalis, 741 Sagapenum, . 730 oil, . . . ■ 236 duris, .... 740 oil 653 Schlippe's, . 160 jalapinus, . . . 741 Sage, essence, 415 spirit, . . . 236 kalinus 74i fluid extract, . 476 water soap, • 742 kalinus venalis, . 742 mountain fl. ext., 468 Saltpetre, . . 70S medicatus, . 742 oil 653 Chili, . . . 752 mollis, . 74i Sago, ... • 153 Salt rheum ointment, 1 105 oleaceous, . . . 740 Saint Germain tea, 753 Salts, Carlsbad arti- viridis, . . . . 742 Jacob's oil, 1098 ficial, . 1 1 16 Saponaceous tooth Johnsvvort, fl. ext ■,- 475 Crab Orchard, . 1116 paste, "33 Salad oil, . . . 639 definition of, • 55 tooth powder, . . "39 oil, Union, 638 lemon, . . 712 tooth wash, 1 1 36 Salaeratus, 702 proprietary, . 1115 Saponaria, fl. extract 469 Sal ammoniac, . 146 Preston's, . . 1 160 tincture, 948 muscatel, . . 1116 Rochelle, . . 706 Sapone, .... 789 nitre, 708 smelling, . 146, 1160 Sarothamnus scopa- prunelle, 708 sorrel, . . . 712 rious, fl. extract, 489 1267 Sarracenia purpurea, Scilla, elixir, comp., 369 Senna and pink root, fluid extract, 476 Scotch whisky, . 1 190 fl. extract, . 484 Sarsaparilla, Ameri- Scrofularia nodosa, and rhubarb, fl. ex. ,484 can, fl. extract, 473 fl. extract, . . 476 syrup 819 coloring, 245 ointment, . 992 tincture, 939 compound, fl. ext., 4S4 Scrofulous syrup, 829 tincture comp., 939 decoction, . . 269 Scudder's alterative, 950 Series, aromatic, 190 elixir, 368 Scullcap, compound, benzene, 190 ext., concent'd, mi fl. extract, . . 4S5 Serpenteria, fl. ext., 464 with iodide of fluid ext., . . 47S , 4S7 oil 653 potassium, mo Scurvy grass, confec. 256 tincture, 939 compounds, I1IO fluid extract, . 474 Serpentary, infusion, 538 and dandelion, fl. spirit, 766 Sessamum, fl. ext., 469 extract, . 484 Scutellarin, 733 Indicum, 639 essence, . .415 ,816 Scutellaria, fluid ex- oil 639 extract liquid, 478 tract, . . 478 487 Seven barks, fl. ext., 475 extract soluble, 424 Sea breeze, perfume, 1 1 55 Sewing machine oil, 641 flavoring, . .415 ,816 foam 1 144 Shake, egg, phosphate , 866 fluid extract, . . 47S Sealing wax, . 216 milk, .... 865 Indian, fl. ext., . 475 varnish, "93 milk punch, 865 pop, 424 Seal oil, .... 642 Shakes, cobbler, 865 resolvent, . 1112 Seawrack, fl. ext., . 474 cocktail, 866 stillingia and red Sebacic ether, . . 7S fruit juice, . 865 clover extract, . mi Sedatives, 1098 Shaker's roots, ext., 1074 syrup, . . 803 , 862 Sedative cough rem. , 1066 Shampoo, barber's, . 1144 syrup, comp.. . . 815 Seed lac 725 Clifford's, . . "44 syr. , soda wat'r,42. , 862 Seeds, 22 dry "44 Sassa bark, fl. ext., 465 oils from, . 642 liquid, . . 704, "44 Sassafras, essence, . 415 Seeley's disinfecting Shark oil, . 642 fluid extract, . . 4D5 solution, 587 Shaving cream for oil 650 Seidlitz measures, . 716 metal tubes, "34 pith, mucilage, 632 mixture, 716 cream "34 Saturated tinctures, 913 powders, 715 Shepherd's purse, fl. Satureja, fl. ext., 469 Selenic acid, . 745 extract, . 461 Sauce pepper, . . 1 194 Selenium 745 Shellac 72S Worcestershire, . 1 1 94 Selenous acid, 745 varnish, 1 [92 Saucers, pink, 876 Seltzer, aperi'nt, 603 III5 Sherbet essence, . 418 Saunders' face powd. "35 water, solution, . 870 extract 4l8 red, fl. extract, 462 Senecin 733 Persian, 863 Savin ointment, . 987 Senecio, fl. ext., 47'', 487 syrup oil, 650 Senega, abstract. 48 Sherry wine, . IOOs Savine cerate, 222 or Seneka, fl. ext., 4"7 Shoe blacking, . extract 450 fluid ext., aqueous, 491 dressing, . . . I I 79 fluid extract, . 460 infusion, dressing bronze, . "79 tincture. 937 and ipecac, fl. ext., 483 dressings, . "78 Savonia cream, . 1134 syrup 818 Show bottle colors, . 250 Saxifrage, small, 11. tincture, . . . 939 Signal oil, 671 ext 402 Senegal gum, . . 726 Silica Scammonium, 729 Seiuka oil, 654 Silicate of potassium, 712 Scammony, . 729 syrup 818 sodium 757 confection, 258 Senna, confection, . Silicates mixture, . . 626 elixir silicic add, powder comp., 719 elixir, compound, Silicon 74S P'MH 7-1 fluid extra t. . 479 Silkweed, fl. extract, i< 1 tincture, . . . 948 fl. ext., alcoholized 480 Silphium, fl. extra* t. virgin 729 fl, e 492 Silver Schiedam schnapps, 1191 fl. ext., comp., . te Schlippe'a salt. . 100 fl, ext., punned, . bromide, 176 Schnapps, schiedam, Scilla, ft. ext., . . 1 [91 and dandelion, fl, c all.., 11. ite. . . . I' 1 ' ■ . . chloride, fl. ext., acetic, 48S infusion, . . . eliminate, . ■7" tract, comp., and jalap, fl cyanide, 1 268 INDEX. Silver, German, . 264 Soap, arsenical, . 743 Soda tartarata, . 747 ink "77 black 743 tartarated, . . . 747 iodide, . . . 173 camphorated, . 743 water, ice cream, . 864 leaf, .... 172 carbolic, 743 water, spoon, . 865 nickel, . 264 castile, mottled, . 740 water syrup, . 848 nitrate, . 173 cerate 222 Sodii, acetas, 748 diluted, . . 174 chlorinated, . . 743 arsenias, . .178 ,747 fused, . . 174 coconut oil, . . 742 ash 749 moulded, 174 cod liver oil, . . 743 benzoas, 747 toughened, . 175 corrosive sublimate , 744 bicarbonas, . . 748 oleate, . 65Q croton oil, . 743 bisulphis, . . . 748 oxalate, 17b erasive 1 169 boras. . . . 199,748 oxide, 175 glycerin, 743 bromidum, 749 phosphate, . . 176 green, .... 742 carbonas, . 749 plating solution, 590 green tincture, 938 carbonas exsiccatus 750 polishes, . . 11S1 iodine 744 chloras 750 polishing powder 1181 jalap, .... 741 chloridum, . 750 potassium nitrate, 174 juniper tar, 744 citro-tartras effer- refined, . 172 laundry, 742 vescens, . 751 sulphate, 176 liniment, 545 hypophosphis, 75i sulphide, 176 marine, 742 hyposulphis, . 752 Silvering and gilding medicinal, . 742 iodidum, 752 pills, . . . 682 mercurial, . . . 744 nitras, .... 752 solution, . . 591 soft, Naples', . . 743 phosphas, . . . 753 solution or polish 1181 oil 5i6 et potassii tartras, 747 Simaba cedron, fl.e> t.,469 palm, .... 742 pyrophosphas, . . 754 Simaruba, fl. extract , 476 plaster, .... 391 salicylas, 754 Simple elixir, 2S0 plaster, brown, . 39i santoninas, 755 cerate, . 218 potassa, 74i sulphas, 755 ointment, . red precipitate, 744 sulphis, .... 755 plaster, . . . 394 salt water, . 742 sulphocarbolas, . 756 syrup, . . 791 soft, .... 741 valerianas, 756 Sinapis alba, . . 640 soft, fig, . . . 743 Sodique phenol, . . 587 nigra, . . . 640 soft, gen. formula, 740 Sodium, .... 746 Skunk cabbage, flui I spirit, .... 771 acetate, .... 747 extract, 468, 46 9, 4S7 sulphur, 744 aluminiate, 757 cabbage tincture, 947 tallow, .... 741 arseniate, .178 747 oil 641 transparent, 744 arseniate solution, 567 Skin ointment, . 1105 turpentine, 744 benzoate, . 747 Skoke or poke root whale oil, . 743 biborate, . . . 748 fluid extract, 46 9. 4S7 white castile, . 740 bicarbonate, . . 748 Slating blackboard 1178 white precipitate, 744 bisulphite, . 748 Slippery elm, fl. ext ., 476 yellow 742 borate, . . . 199 748 Smartweed. fl. ext., 465 Soaps, 738 bromide. 749 compound, 1095 hard, .... 738 bromide syrup, 833 oil 653 hard, gen. formula 739 carbolate, . . . 757 Smelling salts, . 146 soft, .... 738 carbonate, . . , 749 salts or pungents 1 160 toilet, .... 1161 carbonate, dried, 75o Smilacin, . 733 Soaptree bark, fluid chlorate, 75o Smilax sarsaparilla extract, . . . 469 chloride, 750 fluid extract, 476 Soapwort, fl. ext., . 469 citrate, .... 757 Snakehead, fl. ext. 473 Soda 746 citro-tartrate, effer- Snakeroot, button alkali 97 vescing, . 751 fluid extract, 475 ash, 97 ethylate, 757 Canada, fl. ext., 461 baking, 748 ethylate, solution, 567 corn, fluid extract . 469 caustica. 746 hydrate, 746 Virginia, fl. extra :t, 464 chlorinated solution ,566 hypophosphite, 751 white, fl. extract 474 foam, .... 849 elixir, 336 Snakeweed, fl. ext., 473 mint, .... 1128 syrup. . . . 836 Snuff catarrh, 1048 powders, 714 hyposulphite, . 752 Soap, alum-sulphur 744 solution, 566 iodide, .... 752 antimonial, 743 syrups, hot, S66 lactate, .... 757 INDEX. Sodium nitrate, 752 757 Solution, bismuth, . 551 Solution, hypophos. oleate, .... 657 bromo-chloralum, 586 of iron, . 572 oleate solution, 657 caramel, 245 hypophos. of man'e.572 phosphate, . . 753 carbolic acid, . . 569 iodide of arsenic pyrophosphate, . 754 carb. of magnesium ,560 and mercury, . 55o salicylate, . 754 Carlsbad water, . 86S iodine, colorless, . 521 salicylate solution, 591 carmine, 246 compound, . . 559 salicylate, elixir, . 307 chlor. of antimony, 549 Churchill's, . 559 santoninate, . 755 arsenic, . 547 Lugol's caustic, 538 silicate, 757 calcium, . 551 Lugol's rube- silicate, solution, 567 iron, 554 facient, . . stannate, . 757 iron (tasteless), 570 Magendie's, 559 sulphate, . 755 tin 592 iodo-b romideof sulphite, . . . 755 zinc, .... 56S calcium comp., 588 sulphite acid, . . 755 chlorides, 1129 iron oxychloride, . 557 sulphite, neutral, 755 chlorinated lime, . 552 iron pernitrate, . 556 sulphocarbolate, 756, 7S2 chlorinated soda, 566 Javille's, . . . 5S8 tartrate, 757 chlorine, . . 235 552 Kissengen water, 869 tungstate, . . . 967 chromic acid, . 547 lactopeptine, . . 563 valerianate, . . 756 citrate of ammon'm ,549 lactophosphate of Soft soap, 74i ammon'm, strong, 549 calcium, 5 73 Solder, soft, . 191 bismuth and am- iron, .... 573 Soldering solution, . 59i monium, . 570 lime, . . 573 Solferino 154 iron 555 manganese, 574 Solid acids, table, . 57 iron and ammo- lactophosphates, extracts, 441 nium, . 570 compound, 5 74 Solidago, fl. ext., 47o iron and quinine, 555 lime, . . . 55' Solidified glycerin, . 1147 magnesium, 5 6l lime, saccharated, Solomon's seal, fluid potassium, . 565 57i .... 798 extract, . . . 469 citric acid, . 572 lithia, effervescing, 560 Soluble cit. of iron, . 502 citro-chloride of litmus 2 ;i elixir, flavoring, . 277 iron and sodium, 570 '!'-. • • 5 : '> extract of ginger, 421 Condy's, 586 magnesium, cit . . 869 lemon, . 422 Congress water, . 868 M a t te n heimer's mead, 423 Coutaret's white, . 537 disinfecting, . 587 orange, . 424 Darby's prophylac- mercuric, nitrate. sarsaparilla, 4^4 tic, . . '. . 5S7 Monsel's, . . . 557 toiu 42 4 I (eWessely's disin'g,587 Monsel's disinfect- wintergreen, 425 dialysed iron. . 272 554 ing extracts, general dis'ft, Le 1 loyen's 587 morphine, sulph . formula for, . 421 disinfect., < iirondin • ; -7 muriate of opium, flavoring extracts, 421 Dobell's, . . . muriate of tin. 592 Solution 44 Donovan's, nitrate of iron, 556 acetate of alumi- ethylate of sodium, men ury, nium, . . . 547 Farwell's disin'g, mercury, acid, - ammonium, 548 Fehling's, . opium, compound, strong, . . ferric acetate, . 553 depurated, morphii 561 chloride, . 554 . Squibb's, iron 553 citrate, . 555 sedat., 589 potassium, . nitrate, . 556 oxychloride "i iron, 557 albuminate <>l iron sulphate, basic, 557 pepsin ammonia, . 143 547 sulphate, normal 553 perchloride ol iron, 555 strong, . in 547 r's, , . 550 56S strong, . . . 555 Apollinaris water, 868 1 iedrichshall wat mercury, arseniateol gilding 1 1-1 permanganate <<( sium, . . . gutta percha, . .Mil, 566 mate of sodium ,567 hydra stis, • ii.', pernitrate "i iron, arsenious acid, 547 hydro, of morphine peroxide "I hydro., arsenite <>f p hydro, of strychn'e, persulphate ol iron, 557 atropine, sulphate, 551 hypophos., comp., phosphate "t cal., 574 bimeconateol mor- hypophosph ites iron 575 phine, 562 comp.,l fhurchill's lime 574 1270 INDEX. Solution phosphate Sourwood, fl. ext., . 475 Spirit finings, . . II9T of manganese, . 576 Sozodont, .... "37 fioravanti, . 772 phosphates, comp. 577 Spa water, solution, 870 formic acid, 766 phosphates, comp. Sparkman's cholera gaultheria, . 767 concentrated, 576 mixture, . 62S, 1055 honey, compound, 772 phosphorus, comp., 590 Spanishfliegenpflaster ,385 horseradish, comp. 764 phosphorus, Thomp- needles, fl. ext., . 473 juniper, . . . 767 son's, . 589 Spavin cure, . 109S compound, . . 768 potash, effervesc, 565 Spearmint ess., 415 769 lavender, . 76S potassa, 564 fluid extract, . 475 compound, . 919 potassium arseniate 565 oil 649 lemon, . 76S potassium oleate. 657 spirit, .... 769 mastic, compound, 772 preserving pickles, 59i water, .... 169 methylated. 86 preserving vege- Species 75S mindereras, 548 tables, . . . 591 aromaticre, 758 mustard, . . . 771 protoxide of iron, 578 emollientes, . . 758 myrcia, .... 770 Pullna water, . 870 laxantes, . . . 758 neutral 88 Pyrmont water, . 870 lignorum, . . . 758 nitre, sweet, . . 760 pyrophosphate iron 578 pectorales. 759 nitrous ether, . . 760 salicylate of sodium 591 Specific. Australian nutmeg, 770 sedative, Battley's, 589 cholera, . 1054 orange, .... 764 Seeley's disinfect'g 587 Nesbit's, . . . 629 orange, compound, 276 Seltzer water, . 870 Rex Magnus, . 1117 peppermint, 769 silicate of sodium, 567 S. S 1117 perfumed, ... 77o silvering, . . . 591 tinctures, . 913 proof 9i soda, .... 566 Specifics 1117 pure 88 sodium oleate, 657 Sperm oil, . . . 641 pyroacetic, . 772 soldering, . 591 Spermaceti, . . . 226 pyroxylic, . . . 772 Spa water . 870 cerate 220 rectified. 87 strychnine, Hall's, 591 ointment, . 975 rosemary, . 771 subsulphate of iron 557 saccharated, . 227 salt, 236 subacetate of lead, 563 Spiced syrup of rhu- scurvy grass, . 766 diluted, . . . 504 barb, 813 soap, .... 771 sulphate of atropine ,55i tinct. of rhubarb, 935 spearmint, . 769 sulphate of morph., 562 Spicewood, fl. ext., 462 varnish, 1192 sulphate of strych., 579 Spigelia, fl. extract, 472 vulnerary, 772 sulphurated lime, . 592 Spike, lavender oil, . 653 wine, .... 83 tar or pitch, alkaline .59 2 oil, 654 wine, rectified, . 88 tartar tmetic, . 592 Spikenard, fl. ext., . 473 wood 772 tersulphate of iron, 558 fluid ext., comp., 485 Spiritous liquors, 1 148 tin, . . . .592 > 773 syrup, compound, S26 oils 645 Vichy water, . 871 Spiney, Burweed, fl. Spirits, .... 759 Solutions 546 extract, . . . 469 or spiritous liquors, 1187 battery, 586 Spiraea, ulmaria, 736 tin 773 disinfecting, . 586 tomentosa, fl. ext. 476 Spiritus, . . . 8S 759 essential oils. . 409 Spirit of ammonia, 761 setheris, .... 759 homoeopathic, 955 anisated, . 549, 763 aetheris compositus 760 plating, . . . 590 aromatic, 762 a'theris nitrosi, 760 preserving fruit, . 590 fetid, . . . 763 ammoniae, . 761 qualitative, test, . 5S4 angelica, comp. , . 763 aromaticus. . 762 test, . . . 579 to 58 anise, .... 764 compositus, . . 764 volumetric, test, . 584 ants 766 foetidus, . 763 Sorbit, 735 balm, compound, 769 anisi, .... 764 Sorghum sugar, . 734 bone 211 angelicae comp's., 763 Soother, baby, . III3 bryony, compound , 772 aurantii, . . . 764 Soothing syrup, nu- cajuput, . . . 764 aurantii compositus , 276 tritive, 1114 camphor, . 765 camphone, 765 syrup, .... 1113 chloroform, . 80 765 cajuputi, 764 syrup, malt, 1115 cinnamon, . 766 chloroformi, 765 and teething syr. , . 1113 cologne, . . . 88 cinnamomi, 766 Soot oil, .... 263 ether, .... 759 cochleariK, 766 Sorrel, salts of, . 712 compound, . 760 dilutus, .... 92 INDEX. 1*271 Spiritus ferri chlorati S. S. specific, 1 11 7 Stillingia fl. extract aethereus, goS Staff tree, fl. ext., 473 compound, . 485 formicarum, 766 Stahltropfen, . 90S oil 653 frumenti, . 767 Stamp, mucilage, . 1 166 syrup, compound, S29 gaultheriae, 767 Stamping ink for rub- tincture, 94S juniperi, . 767 ber stamps, . 1 176 Stillingin 733 juniperi compositus , 76S ink indelible, . 1176 Stoke"s liniment, 1129 lavanduL-e, . 763 Standard remedies, 1022 Stomach bitters, 43S, 1037 laven';e composita, QIC. Stannate of sodium 757 bitters, extract, . 438 limonis, 768 Stannic acid, . 773 Stone crop, Virginia meliss?e compositus, 769 chloride, 773 fluid extract, 469, 487 menthse piperita, 769 iodide, . . . 773 oil 655 menthce viridis, . 769 oxide, . 773 root, fl. ext., . 469 4S7 myrcice. 770 sulphide, 774 Storecin 1S2 myristicce, . 770 Stannous chloride, 773 St. mghton bitters ext. ,43S odoratus, . . . 770 oxide, . . . 773 Stoughton's elixir, . 381 rectificatus, . . 37 sulphide, 774 Stove polish, . 11S2 rosmarini, . 771 Stannum, . . 773 Stramonium extract, 450 saponis, 771 Staphesacre, ointm't > 98S fl. ext., green plant .487 sinapis 771 Staphisagria, fl. ext , 461 leaves, fl. ext., 467 4S7 tenuior, 91 tincture, 946 ointment, . . 98S 994 vini cognac, 771 Star anise, fl. ext., 469 seed oil, 642 vini gallaci, . . 771 blazing, fl. extract, 475 syrup 825 vini rectificatus, . 88 grass, fl. ext., 473, 4S7 Strassburg turpentine, 663 Spleen mixture, . 630 Starch, . . . 152 turpentine oil, 651 Sponge, platinum, . 695 glace, I1S3 Strawberry ess. or ext. .434 Sponges bleaching, "93 gloss, . . . 1182 juice 777 Spoon soda, . . . 865 glycerite, . . 5i8 phosphate syrup, . 863 Spruce beer, . . . 427 iodide, . 153 syrup, . . . &50 863 beer, extract, . 427 iodide, soluble. 154 Strengthening plaster . 3S5 beer, syrup, 427 85t iodide syrup, . 839 Strontium, . . . 774 essence, 4i5 iodized, . 153 carbonate, . 774 gum 730 mucilage, . . 631 nitrate 774 syrup. . . . 730 paste, good, . 1167 oxide 774 tincture, . . . 730 syrup. ... 27 1, 515 sulphate, . . 774 oil 653 varieties of. 153 Stronger emulsion of Spurge, large, flower- Statice Carolina, fl.e> C..470 cod liver oil, 398 ing, fl. ext., 461 Stavesacre, fl. extra< t, 462 lime water. 397 spotted, fl. ex- Steam atomizers, 996 Strophanthin, . . [195 tract, . . 465 487 Stearic acid, . 1 Strychnia, . . . 130 pill bearing, fl. ext. 4*'' 5 Stearin, . . . 637 sulphate, 131 ipecacuanha, fl.ext. ,465 Stearopten, . . 043 Strychnin. e, sulphas. 131 Spurred or smut rye, Steel 498 Strychnine, . 130 fl. extract, . 477 Stencil ink indelible 1 17') bromide, syrup, . Square, carpenter's, 475 Stcphanotis extract. [I 5 6 elixir 370 fl. extract, . 476 Sterculia accuminat. 1 hydrochlorate, so- Squaw vine, fl. ext., 475 fluid extract. 469 lution, . . . 568 fl. ext. compound, 4S4 Stereotype metal, iron and quinine Squibb's chol. mix., 1055 Stibium, . 155 bromide, syrup, Bfc diarrhoea mixt., . Stilmite, . . . 155 liquor solu. opium, comp. , 588 Sticking plaster, . morphine bromide, Squill, elixir, comp., 3^9 salve. syrup. . . . - - extract 150 Stick cosmetic, var's . >■ t ; ointment, . fluid extract, . . 46 > cosmetic, b «4« oleate fluid ext., acetic, 488 pomades or <>>-., 1X45 salts 1 \2 fluid exl , comp., Ia<- solution, Hall'-, . 59I ointment, . . . 99a Sticky fly paper, '17') sulphate, . . . i |1 oxymel, 6ig Stigmata maydis, il solution, . . - syrup 817 ■ . . . t in. t , Magendie's, 95] syrup, compound, 817 Stillingia elixir, . 37" valerianate, elixir. tincture, . . 938 elixir, compound, Strychnos, Ignada, fl. vinegar, 55 fluid extract, . .47 2, 487 extract, , , . 12JT2 Styptic, colloid, 244 , 243 Sulphate of calcium, 210 Sulphite of sodium, collodion, . 243 cerium, . . 226 neutral, . 755 antiseptic, . 243 chromium, . • 239 Sulphites 781 Styracin, .... 182 cinchonia, . . 112 Sulpho-acids, . . 782 Styrax, .... 1S2 cinchonine, . 112 Sulphocarbolate of benzoin, 182 cinchonidine, . in sodium, . . . 756 oil, 654 codeine, • "4 zinc, .... 1019 Styrol, .... 182 copper, . • 265 Sulphocarbolates, 782 Subacetate of lead, daturine, IJ 5 Sulpho-carbolic acid, 782 cerate, 221 duboisine, . . 116 Sulphocarbonate of lead, glycerite, 519 hyoscyamine, . 118 potassium, . 712 lead, glycerine indigo, . . ■ .877 Sulphocyanateof ally -134 ointment, 978 iron, • 509 ammonium, 150 lead, liniment, 545 and ammoni urn, potassium, . 712 Subcarbonate of iron 5" 503, 5iO Sulphocyanide of allyl, 650 bismuth, 195 dried, • 510 Sulphocyanides, . 782 Subchloride of bis., 196 exsiccated . 510 Sulphocyanogen, 782 mercury, 525 granulated, . 5'o Sulphovinates, . 782 ointment, 982 precipitated . 510 Sulphovinic acid, 782 Sublimate, corrosive, 526 lead, . . • 699 Sulphur, .... 778 Subnitrate of bis., . 196 lithium, . • 596 acids, .... 781 Suboxide of copper, 266 magnesium, . 601 amorphous. 780 Subsulphate of mer- magnesium, dr ed, 603 balsam 186 cury, yellow, 530 manganese, . 614 black, .... 780 Succi 775 mercury, • 529 brown, .... 780 Succinate of ammo- morphine, . . 121 bromide, 781 nium, 150 nickel, . • 634 chloride, 781 Succinates, 724 potassium, • 709 confection, . 259 Succinic acid, 724 quinine, • 127 crude 780 Succinum, 724 quinidine, . • 125 etherate, 82 Succus, alterans, 1027 sanguinarine, . • 130 fuscum, 780 belladonna;. 775 silver, . . 176 hepar, .... 78i conii, .... 775 sodium, . • 755 iodide, .... 780 hyoscyami, 775 strontium, . • 774 lac 779 juniperi inispissatus ,775 strychnine, . • 131 liver of, 701 liquiritia;, . 776 strychnine solu ti'n, 579 lotion, .... "93 depuratus, . 776 zinc, . 1019 lotum, .... 778 scoparii, 776 zinc ointment, • 992 milk of, ... 779 taraxaci, 776 Sulphates, . 781 ointment, . 988 Sugar, 734 Sulphethylates, . . 782 ointment, alkaline, 989 barley, .... 735 Sulphide of allyl, • 134 precipitated, . 779 beet, .... 735 ammonium, • 149 p'rrecipitatum, 779 cane 735 antimony, . • 158 red 780 coating pills, . 680 antimony, golc en, 160 roll, ... 778 780 coloring, burnt, . 245 barium, . . 1S8 salts of, ... 781 grape, .... 515 cadmium, . . 204 soap, .... 744 lead, .... 696 calcium, 209, 210 sublimatum, . 778 lemon, .... 1 194 gold, . . . 180 sublimed, . 778 milk, . . 542 745 hydrogen, . . 781 vivum 780 Sugars, .... 733 iron, • 512 washed, . . . 779 non-fermentable, 735 potassium, . • 712 Sulphurated antimony .159 Sulphantimoniate of Sulphides, 778, 781 lime 209 antimony, 160 calcium, . 210 solution, 592 Sulphate of aconitine, 104 tin, . . . • 774 oil, 186 aluminium, . . 139 Sulphite of ammo ruum, 150 oils, 643 ammonium, 148 barium, . . 188 potash ointment, 986 antimony, . 160 lime, . . . . 210 potassa, 701 atropine, 106 magnesium, . 601 Sulphuret of antimon. 158 barium, .... 188 potassium, . . 709 Sulphurets, . 778, 78i beberina, . 107 silver, . . 176 Sulphuretted hydro., 781 berberine, . 109 sodium, • 755 Sulphuric acid, 56, 73 78r cadmium, . . . 204 sodium, acid, . • 755 aromatic, 73 1273 Sulphuric acid, diluted, Sweet clover, fl. ext. 475 Syrup bromide of iron 799 c 5. 74 fern, fl. extract, . 474 bromide of iron, taste- anhydride, 78i flag, candied, . 260 less, 831 ether 78 flag essence. . 410 bromide of iron, qu - Sulphuris iodidum. . 7S0 flag, fl. extract. . 459 nine and s try ch., 833 Sulphurous acid, 56, flag syrup, . S23 bromide of morph., 831. 74 ,781 flag tincture, . . 891 bromide of morph. anhydride, . 7S1 gum 1S2 and strych., 833 Sumach, aromatic fl. gum tree, fl. ext., 462 bromide of potass. , 833 extract, . 469 487 gum syrup, . . 824 bromide of quinine, 831 Chinese, fl. ext., . 437 marjoram, fl. ext., 475 bromide (if quinine fluid extract, . 472 marjoram oil, . 653 and morphine, . 832 Sumbul, elixir, . 37' orange, fl. extract, 473 bromide of quinine, compound, . . 371 quinine, 129 mor. and strych., 832 extr. for perfumes, "53 spirit of nitre, . 760 bromide of sodium, 833 fluid extract, . 462 tincture of rhubarb 935 bromide of strych., 832 tincture, «... 940 violet oil, . . 653 bromide of strych., Summer savory, fl. Sydenham's laudanum ,929 iron and quinine, S33 extract, . . . 469 Sympathetic inks, . 1177 bromide of strych. oil, .... 653 Symphytic syrup. 824 and morphine, . 832 Sun cholera mixture, 629 Symphytum officinale, buckthorn, . . . 811 Sundew, fl. extract, 462 fluid extract, . 476 calamus, . 823 852 Sunflower, fl. ext., . 469 Symplocarpus, fluid calcium and iron, seed oil, . . . 642 extract, . . 469 487 lactophosphate, 841 Suppositoria, . . 782 Syrup, 791 calisaya, S52 acidi carbolici cum acacia, .... 792 calisaya phosphate, 852 sapone, . 789 acacia mucilage, . 39" Canada balsam, . S24 tannici, . 789 acid phosphate, . 861 capillaire, . . . 522 tannici cum sa- adiantum, . 822 caraway, . ^3.852 pone, . . . 789 albuminate of iron cardamom, 823 hydrargyri, . . 789 and sodium, 840 carophylles, 32 ) iodoformi, . 789 althaea 794 carrageen, . . . 822 morphime, 789 almonds, . . . 794 carrageen comp., 826 cum sapone, -.,, alterative. . 826 catawba, 852 plumbi composita, 790 ambrosia, . 850 ceanothus comp.. Suppositories, . . 782 ammoniac, . . . 824 chamomile, anodyne, 7-1 aniseed, . . 823 champagne, astringent, 785 anthemis, . 823 cherry S53 antiseptic, 786 antiscrobutic, . . 826 cherry phosphate, 853 aural 789 apple 850 cherries, 798 gelatin, . . . 514 apricot 850 chimaphila, genera] formula, . 783 aralia, compound, 826 chloral hypnotic, . 787 artemisia compound, 826 chloride ol amnion nasal 789 asafetida, . 824 ium 843 pile 7')" .1 ,iniin compound, 826 chocolate, . purgative, . . . 790 asparagus, . 824 chocolate, hot, 867 rectal 784 bayberry bark. 823 cinchona, . . . urethral, 787 balsam Peru, . . 824 cinnamon, . .7 vaginal, 788 ■ ,851 citrate "I iron, vermifuge, . . . 790 belladonna, . . 824 citrate of iron and Svapnia 825 oin, 824 quinim 834 elixir 571 birch beer, 42; ,851 :.■ ot iron, syrup 825 bitter-sweet, . . 823 quin. and strych S. V. R 88 blackberry, . 814 . B50 citrate ol ir< 01 ami Swamp dogwood, fl. blackberry aromati strychnine, . . B34 ct, . . . 474 blackberry root, . citric acid, • • . Swandown fa< e pow black cherry, ■ 850 claret 854 der 1 135 blood and liver, cloves balm, il. ext., 475 blood root, coca basil oil, blueberry, , . . 857 fee, . . .417 . 854 drily oil, brandy, . offee, hot, . . 867 cicily. ll. extra* t, 475 brum, of amonium 833 a ic 1274 INDEX. Syrup colchicum, 823 Syrup hypophosphite Syrup lactophosphates coltsfoot, . 823 of calcium, so- compound, . S42 comfrey, S24 dium, potass. lactucarium, . . 806 conium, . 82s and iron, . . 835 Aubergier's, . 806 copaiba, 824 iron 836 lemon, . 807, 850, 857 corsican moss, 822 iron and calcium, 836 phosphate. . . 857 corydalis compounc .827 iron and manga- soda water, . . 423 cough, Jackson's, 628 nese, . 836 lime, .... 798 cream 855 lime, .... 834 fruit, .... 858 cubeb, . 823 lime and soda, . S35 fruit phosphate, 858 curacoa, 855 lime, soda and limes 850 currant, S50 855 potassa, . . 835 liquorice compound, 827 dandelion, . 825 lime soda, po- liquorice extract, . 825 datura, . 825 tassa and iron, 835 liq. root, . . 808, 822 dextrin, . 271 515 manganese, 836 liquidambar, . . 824 dialysed iron, S40 sodium, . 836 lobelia, .... 823 digitalis, 824 hypophosphites, . 803 mace, .... 858 don't care, . 855 Churchill's, . . 804 maiden hair, . . 822 Dover's, 828 compound, . . 835 malto 866 dulcamara, . 823 comp., Fellow's, 837 malt hop phosphate, 858 Easton's, . 802 comp., with iron, 804 malt and tar cough, 612 egg nogg. • 856 comp., with lac- malt tonic, . . . 858 erythroxylon, 825 topeptine, 838 manna, . . . . 80S eucalyptus, 823 comp., with qui- maple, .... 858 euonymus, . 825 nine and strych. 837 marrubium, . . 823 fennel, . 823 comp., iron, qui- marrubium comp., 82 i flavored, 830 nine and strych. 838 mead 423 foxglove, . 825 lime, iron, soda mead excelsior, . 424 fumitorv, . 824 and potassa, . 804 milk punch, . . 856 galls, '. . 823 hyssop 823 mitchella compound, 828 garlic, . 793 Iceland moss, . 822 morphine, . . . 843 garlic, compound. 794 compound, . 826 mugwort, comp., 826 German cough, . 1064 Indian sarsaparilla, 803 mulberry, . . 850, 858 gillinia, .... 823 iodide of calcium, 838 mulberries, . . 809 ginger, . 422, S21 856 iodide of iron. 800 muriate of amnion., 843 ginger ale, . . 422 856 iodide of iron, taste- nascent phenic acid, 844 glycyrrhiza, S22 less, 839 nectar 859 glycyrrhiza comp., 827 iodide of iron and nectarine, . . . 859 golden 874 manganese, . 839 nutgalls, . . . 823 grape, . . .850 856 iodide of lime. S38 nutmeg, . . . 858 grape phosphate, . 856 iodide of manga- opium 825 guaiacum, . 824 nese, . 839 opium and ipecac, 828 guarana, 825 iodide of starch, . 839 orange, 795, 850, 859 gum arabic, 792 ipecac, .... 805 blood, . . . 860 hedge mustard, . 824 ipecac and opium, 828 flowers, . 796, 860 helminthocortus, . S22 jalap, .... S23 Malta, red, . . 860 hemidesmus, . 803 juniper berries, 823 Maltese, . . . 860 henbane, . . . 825 krameria, . 806 phosphate, . . 859 hive 817 lactate of iron, 840 soda water, . 424 hoarhound. S23 lactopeptine, . 842 orgeat, . . 794, 860 hoarhound comp., 828 lactopeptine comp. 842 Ottawa beer, . 425, 851 hock 857 lactophosphate of oxide of iron, . . 801 hound's tongue, . 824 calcium, . . 797 841 partridgeberry com- huckleberry, 850 ,857 calcium and iron 841 pound, . . . 828 hydriodic acid, 793 cal. and pepsin, 841 peach, . . . S50, 860 hyoscyamus, . 825 iron, .... 841 pear, . . . 850, 800 hypophosphite of iron and lime, . 841 pear phosphate, . 860 calcium, . . . 834 lime, . . . 797 841 peppermint, . . 808 calcium and so- lime and pepsin, 841 pepsin, .... 843 dium, . 835 manganese,'. 841 Peruvian beer, 425, 851 calcium, sodium lactopho s p h a t e s phosphate of cal'm, 844 and potas sium 835 cal., iron mang., 842 iron, . . 801, S44 INDEX. 1275 Syrup phosphate of Syrup squill, . . . S17 Syrup hypophosphi lime 844 compound, . 817 turn, . . . . 803 manganese, 844 starch, ... 2^ 1, 515 hypophosp h i t u n 1 compound, . 845 stillingia, comp., 829 cum ferro, . S04 quinine, . 846 stramonium, . 825 ipecacuanha?, . S05 quinine and iron 847 strawberry, . 850, 863 krameria?, . 806 phosphates of iron, phosphate, . 863 lactucarii, . 806 quinine and svapnia, 825 limonis, S07 strychnine, 802 S47 sweet flag, 823 liquiritfce, . . SoS phosphates, comp., S45 sweet gum, 824 manna?, 808 Phytolacca, comp., 828 symphytic, S24 mentha?, SoS pineapple, . . S50 861 tar, .... 809 mori, . . . 809 phosphate, . 86 1 taraxacum, 825 papaveris, . . 809 pipsissewa, 824 tea, .... 863 picis liquid. e, . 809 plum, . . . S50 ,86i triple phosphates 847 pruni Virginians Rio poke, compound. 82S tolu, . . . 823 rhamni cathartica. , 811 prune, . . 850 861 from extract. 425 rhei, . . . S12 protoxide of iron, 847 turkey corn, comp ., 827 rhei aromaticus, 813 pulmonary, 828 tussilagino, 823 rhceados, . . 813 pyrophosphate of valerian, S24 rosne. . 814 iron 347 vanilla, . . 8: 4,864 rosa? gallica?, . . S14 queen's root comp. , 829 violets. . . S2 3. 864 rubi, . . . S14 quieting, 1114 wild cherry, 81 o, 853 rubi Idrei, . . . 815 quince, . . . S50 862 wild cherry, comp .,1065 sarsaparilla? com - quinine, iron and white pine, comp , 1064 positus, . . 815 strychnine, . . 802 wintergreen, . . 864 scilke, . . . • 817 raspberry, . .815 862 soda water, 42 5. 864 scillre, compositu ., 817 black, . . . 8 so worm, . . 1123 senega;, . 818 phosphate, . . 862 yellow dock, com p., 829 senna?, . S19 red, .... 850 yerba santa arom t., 829 simplex, • 79i red cherry, . . 850 Syrupi, 790 tolutanus, . . . 820 poppy,' . . . 813 Syrups, . . . ■ 79° zingiberis, . . . 821 root compound, 827 aromatic herbs, . 808 System renovator, . 1040 rhamnus, . 811 chemical substant es,830 rhatany, . . . 806 fruit, . . . 777 rhubarb, . . . 812 fruit juice, . . ■ 849 T aromatic, 813 phosphate, 86i and potassium, S20 soda hot, . 866 Tabacum, fl. ext., • 476 soothing, 1114 soda water, 84S Tabella?, . . . . 871 spiced, . 813 sooth'g and teeth' g,i"3 nitroglycerin!, • 871 rock candy, . . 848 wine, . 864 Tablet, lily white, . 1 136 root beer, . 427 851 Syrupus, . • 79i Tablets, '. . . . 871 rose, . . 814, 862 acaci.e, . 792 compressed, . 872 rubus, . 814. 823 acidi cilrici. 793 diarrhoea, . . . 1070 rumex, compound, -j , acidi bydriodici, 793 dyspepsia, . . 1072 <>n -~l allii 793 fruit, . . . 87a sanguinaria, . 823 althaea, . 794 hypodermic, com sarsaparilla. 803 862 amygdala.', . • 794 ed, . compound, . ->-- aurantii, . . 7os nitroglycerin, , . S71 soda water, 424 862 aurantii florum, 79 6 tooth, . . . 11 19 scrofulous, . . 829 calcis, . . 79? worm, . . . 11.:, senega, .... 818 calcii i-i' tophosp, . 797 1 acamahaca, . . 1-1 eneka 818 cerasorum, . Jder, il. ext., 1' " senna 819 chloral, . . . 700 • 215 sherbet, 863 i innamomi, soap, 741 simple 7oi ferri bromidi, . • 7oo Tamarac gum, . 7 JO for SOda w.it.r, 848 iodidi, . . il extract, . . soothing, . 1113 oxydali SOlubilis, Sol tincture, ■ 7^" spikenard, comp., 826 phospl . 801 Tamar [ndien, . spruce beer, . 427 851 quuunse 1 il :h- 1 .111.11 .turn. tl. ext 17'' spruce gum, . nin 1 phospc 1. 11111. itenf .iltimiiiiu 11. 1 |0 Squaw vine, eomp., 828 hemidesmf, . 803 bismuth, ■ , • 107 1276 INDEX. Tannate of lead, 699 lead ointment, 986 pelletierine, 123 Tannic acid, . . 5 7,873 glycerite, 517 ointment, 970 suppositories 7S9 vvith soap, . 789 troches, . . 961 Tannin, 873 Tansy, fluid extract 476 oil, .... 653 Tape worm remedy, 1125 Tapioca, . 153 Taraxacum, elixir 322 compound, 32 2, 371 extract, 450 fluid extract, . 479 Tar 694 655 barbadoes, birch, 694 oil, . . . 649 coal, 694 glycerite, . 522 compound, . 522 juniper, 64 8,694 and malt cot & L syrup, . . 612 oil, .... 6. 9,694 ointment, . 9S4 pine, 694 solution, alkali le 592 syrup, . 8O9 169 water, . wine, IOI2 Tartar, cream, . 703 soluble, . 711 crude, . • 703 emetic, . 156 elixir, • 372 ointment, • 971 solution, • 592 wine, . . . • 998 sal 704 salts of, • 704 Tartaric acid, e 7. 703 Tartrated antimony , 156 ointment, • 97i antimony and pot is., 156 elixir, . • 372 bismuth, • 197 chinoline, . . 130 iron, ■ 504 soda, . . . 7 36, 747 Tartrate of iron an 1 ammonium, • 503 potassium • 504 magnesium, ■ 603 manganese, . 615 morphine, . . 122 potassium, . . 710 acid, . . • 703 Tartrate of potassium neutral. . . . 710 and sodium, . 706 sodium, .... 757 zinc, 102 1 Tartrates 703 Tasteless castor oil, 397 cod liver oil, . . 397 iodide of iron, . 506 tincture of iron, . 570 Tea, blood purifying, 1045 Hamburg, . . . 1107 fluid extract, . . 476 labrador, fl. extract, 469 laxative, . 758, 1052 oil, . . . 653 pectoral, . 759, 1107 rheumatic, . . .1110 St. Germain, . . 758 syrup, .... 863 vermifuge, . . . 1125 wood, .... 758 worm, .... 1 125 Teas, 758 Tecoma radicans, fl. extract, . . . 476 Teething and sooth'g syrups, . . .1113 Telluretted hydrogen, 874 Telluric acid, . . 874 Tellurium, ... 874 dioxide, . . . 874 trioxide, . . . 874 Tellurous acid, . . 874 Terchloride of anti- mony, . . 160, 549 bismuth, . . . 197 Terebene, . . . 651 cough mixture, . 1067 vapor, .... 996 Terebinthina, . . 662 Canadensis, . . 663 Terminations of acids — ous — ic, . . 56 alkaloids — ia — ine, 99 glucosides — in, . 515 neutral prin. — in, 515 resinoids, etc. — in, 732 salts — ite — ate, . 56 salts — ide, ... 56 terpenes — ene, . 643 stearoptens — ol, . 643 Terpenes, . . . 643 Terra japonica, . 727, 877 Test papers, . . . 231 Test solutions, quali- tative, ... 579 acetate of copper, 579 acetate of lead, 580 acet. of potassium, 580 acetate of sodium, 580 albumen, . . 580 Test solutions am- monio-nitrate of silver, . . 580 sulp. of copper, 580 sulph. of mag., 580 bichromate of potassium, . 580 bitartrate of sod., 580 boric acid, . . 581 bromine, . . 581 carb. of ammon., 581 carb. of sodium, 581 chlor. of ammon., 581 chlor. of barium, 581 calcium, . . 581 gold, . . . 581 chrom. of potas., 581 ferric chloride, 581 ferricyanide of potassium, . 581 ferrocyanide of potassium, . 581 ferrous sulphate, 581 gelatin, . . . 581 hydrosulphu r i c acid, . . 582 hoposulphite of sodium, . . 582 indigo, . . . 582 iod. of mercury and potassium, 582 potassium, . 582 iodine, . . . 582 isinglass, . . 582 magnesium, . 582 mercuric chloride, 582 Meyers', . . 582 Nessler's reagent, 583 nitrate of barium, 582 silver, . . 582 oxalate of am- monium, . . 582 permanganate of potassium, . 583 phosphate of am- monium, . . 583 sodium, . . 583 picric acid, . . 583 platinic chloride, 583 potassio - cupric tartrate, . . 583 mercuric iodide, 583 stannous chlo., 583 sulphate of cal., 583 copper, . . 583 magnesium, . 584 potassium, . 584 silver, . . 584 sulphide of am- monium, . . 584 sulphite of sod., 584 tannic acid, . . 584 INDEX. 1277 Test solution tar- Thymus fluid ext., 476 Tinctura cinchona; taric acid, . 5S4 Tilia, fluid extract, 476 composita, . 901 tincture phenol- Tin 773 cinnamomi, 902 phthalein, . 584 chloride, 773 cocci 903 yellow chromate solution. 592 colchici. 903 of potassium, 5 84 foil 773 seminum, 903 Test solution, volu- hydrated per oxid e. 773 colocynthidis, . 903 metric, ... 584 iodide, . 773 conii, .... 904 bichrom ate of liquor, . 592 croci 904 potassium, . 584 mordants, . 774 cubelxe, . . . 905 hyposulphite of mucilage, . 1 166 digitalis, . . . 905 sodium, . . 5S5 oleate, . 659 1 >i »veri, .... 9i7 iodine, ... 585 oxide, . 773 ergotre, . . . 906 nitrate of silver, 585 paste, 1167 ferri acetatis, . . 906 oxalic acid, . . 585 polish, . . . 11S2 acetici setherea, 907 soda 585 protiodide, 773 chloridi, . 907 Test solutions, 579 to 585 solution, 592 chlorati aetherea 90S qualitative, . . 379 spirits, . 773 perchloridi, . . 908 volumetric, . . 584 sulphide, . . 774 pomatia, 908 Trommer's. . . 734 Tinctora, . . . 875 formicarum, . 949 Tetrane 213 Tincture , . 880 gallre 909 Tetryl, . . ,85, 201 Tinctura absinthii, 881 gallarum, . . . 909 Tetter ointment, . 1105 aconiti, . . 882 gelsemii, 909 Thallina 132 aloes, . . . 883 gentians, . 910 Thalline 132 composita, . 884 composita, . 910 Thallium, ... 874 et myrrhse, . 884 guaiaci, 911 Thea Chinensis, fl. amara, . . . 885 ammoniata, 912 extract, . . . 476 arnica? tlorum, 885 herbarum recentium,gi3 Thebaine, . 666 radicis, . 886 humuli 9U Theilemann's cholera aromatica, . 886 hydrastis, . . . 914 drops, . . . 1055 asafcetidse, . 887 hyoscyami, . . 915 Theine no aurantii amari, 887 ignatise, . . . 915 Theobroma cacao. dulcis, . . 888 ioili 915 .... 237, 640 recentis, 888 iodinii, composita, 916 fluid extract, . 476 belladonna.-, 889 ipecacuanha-, . 917 oil, 640 benzoics, 889 et opii, . . . 917 Theriaca, . . . 257, 874 benzoini, . 889 jaborandi, . . . 917 Andromachi, . . 875 composita, . 890 jalap.x 81S Thibault's balsam, . 1035 blattre. . . . 95o kamalse, 94S Thimbleweed, fl. ext. ,476 bryoniie, . . 890 kino 91S Thiosulphuric acid, 781 buchu, . 891 kramerise, . Thistle blessed, fl. ext.,473 calami, . . . 891 laricis 9] 1 '1 bompsonian com- calendulae, . . 891 lavendulse comp'a, 919 position powder, 720 calumbss, . . 892 limonis, 920 Thompson's solution camphor.x compo ... 893 lobelias, 921 phosphorus, . . 589 cannabis [ndicse, 893 lobelias setherea, . 921 Thoroughwort, fluid cantharidis, 894 lupuli oil extract, . 46a, r: capsict, . . . 894 lupulin.i-, . . . 921 Thuja articulata, 726 cardamomi, 895 matico 922 octidentalis, fluid composita, . B96 most In 922 extract, . ■ . 11 i 1 1 t ■ , . 896 myrrhse, 923 oil torei, . . B97 nucis vomicae, tincture, . . 947 1 J111. ( omposi opii Thyme, fluid extra' t, 476 < iiin.i-, . 900 ammoniata, , . 927 oil 1 posita, 'c benzoica, I hymene, 651 chinoidine, 898 camphorata, Thymol, . . chiratse, . . crocata, . . . chloral liniment, . [004 chloroform] com deodorata, . . ointment, . . . 1105 ... 898 simplex, . 927 toothache remedj , tiai it morphinse, pimpinellae, . . 931 vapor, .... cimicifugW, physostigmatis, 93] Thymus vulgaris, . 651 1 in. boa e, . podophyTli, 1278 INDEX. Tinctura pyrethri, . 932 Tincture antiscrobutic, 949 Tincture chloride of quassia, 932 antispasmodic, • 950 iron. . 907 quininae ammoniatc .933 ants, • 949 etherial, . 908 rhatanhia>, . . . 919 aralia spinosa, • 947 (tasteless), 570 rhei, 934 arbor vita, . • 947 chloroform, 898 aquosa, . 934 arnica flowers, . 885 and morphine, 899 aromatica, . 935 root, . . . 885 chrysophyllum, 947 dulcis, 935 aromatica, . 886 cimicifuga. 899 et senna;, 936 asafetida, . . 887 compound, . 949 vinosa, . 936 etherial, . • 952 cinchona, . . 900 sabinae 937 aspidosperma, • 947 ammoniated, 949 sanguinarire, . . 937 astringent, . • 949 compound, . 901 sanguinaria; ace- avena sativa, con- cinnamon, . 902 tata composita, 949 centrated, . 1129 cloves, . 947 sanguinaria; comp., 949 balm gilead buds, 946 cocculus Indicus, 946 saponis viridis. 938 balsam copaiba, . 946 cochineal, . 903, 947 scillae 938 fir, . . • 946 ammoniated, 950 senega;, 939 Peru, . . • 947 cockroaches, . 950 senna;, .... 939 baptisia, • 947 colchicum, 903 serpentariie, . 939 belladonna, . 889 seed compound 950 strychni, 925 benzoin, . 889 colocynth, . 903 sumbul, . . . 940 compound, . 890 conium, 904 tolutana, . . . 940 bitter, . . • 885 leaves, 946 tonico-nervina, 908 bitter orange p eel, 887 contrayerva. . 948 Valerianae, . 941 black cohosh, • 899 coptis trifolia, 946 ammoniata, . 942 black cohosh, c amp., 949 corydalis, . . 948 retherea, . . . 942 blessed thistle, • 947 compound, . 950 vanilla; 942 blood root, . • 937 coto, . . . 948 veratri viridis, 943 acetous, . • 949 cranesbill, . . 946 zingiberis, . 944 compound, • 949 croton seed, 948 zingiberis fortior, . 945 blue cohosh, ■ 947 crown bark, 381 Tinctura; 880 compound, • • 949 cubeb, . 905 Tincture absinthium blue flag, . • 947 Culver's root. 948 compound, . ■ . 948 boldo, . . • 947 curcuma, . 950 acetate of copper, 94S bryonia, . 890 delphinum, 946 acetate of iron, 906 buchu, . . . 891 digitalis, . . 905 acet. of iron etherial,g07 cactus, . . ■ 949 dracontium, 947 acet. of iron, Rade- calabar bean, • 93i ergot, . . . 906 macher's, 907 calamus, . 891 etherial, . 952 aconite 882 calendula, . . 891 erigeron, 94S etherial, . 8S3 calumba, . 892 eucalyptus, 948 Fleming s, . 883 camphor comp Dund, 893 euphorbium, . 946 leaves, 883 canella, . • 946 ferrated extract E root 8S2 cannabis, Indi an, 893 apples, 90S actasa, .... 899 cantharides, • 894 fleabane, . . 948 ailanthus, . . . 946 etherial, . • 952 foxglove, . 905 alkanet, 947 capsicum, . • 894 galangal, . 947 aloes alkaline, . 948 cardamom, • 895 galbanum, . 946 comp., 380, 3S1 , 884 compound, . 896 gelsemium, 909 and myrrh, . 884 carduus, • 947 gentian, » 9 ID amber 947 cascarilla, . . 896 ammoniated, 950 amber alkaline, 94 S castor, . . • 897 compound, . 910 ambergris. . 946 etherial, . • 952 comp., improve d, 911 ambrette, . 947 oil beans, • 948 geranium, . 946 American hellebore . 943 catechu, • 897 ginger, . . . 944 ammonia comp., . 948 compound, • 897 ginger, strong, 945 ammonio-chloride of catarrh root, • 947 gold thread, 940 iron, .... 949 caulophyllum, • 947 golden, . 102S anchusa, 947 compound, • 949 golden seal, . 914 anemone, . 947 chamomile, • 946 gratiola. 947 angustura, . 947 chinoidin, . . 898 green hellebore, 944 anthemis, . 946 chirata, . 898 green soap, 938 INDEX. 1 285 Zinci acetas, . 1015 Zinci oxidum, 1018 Zincum 1015 carbonas, pra;cipi- phosphidum, . 1018 granulatum, . . 1020 tatus, . . . 1016 sulphas, . . 1019 Zingiber, rl. extract, 460 bromidum, . . 1016 sulphocarbolas, 1019 Zoedone 871 chloridum, . 1017 valerianas, . . 1020 Zugpflaster, . . . 395 iodidum, . . . 1018 Zinco-lead plaster, 394 INDEX. 1279 Tincture guaiac, 911 Tincture of opium Tincture of strych alkaline, . 912 camphorated, 928 Magendie's, • 951 ammoniated, 912 compound, 62 9.951 sumbul, . . • 940 Dewees', 912 deodorized, 929, 930 sweet flag, . 891 guaiacum wood, 94S deod.. with nitre, 951 orange peel, . 888 guarana, 947 and ipecac, . 950 tamarac, • 730 hemlock, . . 904 and saffron, 929 thuja, . . . • 947 henbane, 9' 5 orange fruit, . 888 tolii • 940 hops, . . . 9U orris. 94S turkey, corn, . • 948 horse chestnut, 946 oxgall, . 946 Turneria, . ■ 950 Huxham's, 901 Pareira brava, 946 valerian, • 94i hydrastis, . 9M pellitory, . . 932 ammoniated. • 942 hydrastis, comp., 950 phenol-phthalein, 5S4 etherial, . • 942 hyoscyamus, . 915 perchloride of iron, 908 vanilla, . • 942 ignatia, . . . 915 persionis, . 247 veratrum viride, • 943 iodine, . 9'5 phosphorous comp., 951 Norwood's, • 944 iodine, colorless, 521 Phytolacca, 948 vittie vayr, • 947 iodine, compound , 916 pilocarpus, . . 917 Warburg's, • 951 iodine, decolorizec I, 950 pimpinel, . 93i white pine, 95 :, 1064 iodine, etherial. 952 podophyllum, . 932 wild indigo, • 947 iodoform, etherial , 952 poke, 948 wormwood, . 881 ipecac, . 917 poison oak, 947 yellow jasmin. . 909 ipecac, compounc . 95o prickly elder, . 947 zedoaria, • 947 ipecac and opium 917 Pulsatilla, . 947 compound, . • 952 iris Florentina, 94S pyrethrum, 932 Tinctures, . 880 iris versicolor, 947 quassia, . . 932 etherial. • 952 Indian cannabis, 893 quebracho, 947 fresh herbs, • 913 Indian hemp, . 893 quillaya, 94S green, . • 913 jaborandi, . 9H quinine, 933 homoeopathic, • 953 jalap, 918 quinine, ammoni mother, . • 953 jodi 916 ated, . . . 933 saturated, . • 913 kino, . . . 918 red gum, 948 specific, . . • 913 krameria, . . 919 rhatany, 919 unofficial, . . • 945 lactucarium, 946 rhododendron, 946 to per cent.. • 945 larch, 919 rhubarb. . . 934 15 per cent., • 946 laurel, . . . 946 aqueous, 934 20 per cent. . • 947 lavender, comp., 919 aromatic, 935 Tisanes, . . . • 956 lemon, . 920 compound, . 95' co, B. extracl 176 leptandra, . 948 and senna, . 936 oil, . . . • "53 lobelia, . 921 spiced, . 935 ointment, . . compound, . 950 sweet, 935 Toilet preparations , 1131 im, «omp M 950 vinous, . 93" powder, violet. . [i 36 etherial, . . 92 I. 952 rhus toxicodendn n.947 rose, . . 1 1 )6 lupulin,. . . 921 ricinus, . 94S soaps, . . . MM marigold, . 89I rose 948 vinegars, . . . 1 l6l mastic, . . . 948 rosmaiy, waters, . . II02 matico, . . 92 lera, . . 948 ■-. . 18] monesia, 947 saffron, . . :■> Ursina 641 compositum, ■ <>:•> 1 nil a dioica, fluid iodidi rubri, extract, . . . 476 nitratis, . . . .,-'i ■ may. lis, fl. dilutium, . f..r perfumes, . . 1 154 plant, fl. extract, . 475 syrup, . . - ) 1. §64 tincture, 942 tonka extract. . 4J.. Vanillin 99s di hydro, \ - anici. . . carbolic add, . chlori 996 coninae 996 loti, . . 996 1282 INDEX. Vapor iodi, menthol, nitrate of amyl, olei pini sylvestri; terebene, . thymol, . Vapors, . . . Vapores, . . . Varnish asphaltum black, balsam, China, balsam, Japan, carriage, copal, crystal, . . . demar, . . . furniture, . glass, label, . . . map, sealing wax, shellac, . spirit, transfer, wax, V T arnishes, Vaseline. . carbolized, . Vegetable alkali, drugs, . healing balsam, oils, .... preserving solution Velpeau's diarrhcea mixture, . 67 Venetian red, Venice turp. , . turp., factitious Veratria, . Veratrina. . Veratrin, . Veratrine, oleate, . ointment, Veratrum viride elixir album, fl. extract,. sabadilla, fl. ext., 90 996 996 996 996 996 995 995 724 182 182 1 193 1 193 1 193 "93 "93 "93 1 192 "93 "93 IIQ2 1 192 II92 "93 1192 , 934 969 98 19 1035 642 . 590 629 512 651, 663 663 133 133 733 133 05b 990 376 469 462 viride, fl. ext., 460, 4S7 viride tincture, Verbascum thapsus fluid extract, Verbena essence, hastata, fl. ext., oil, .... Verdigris, . . . cerate, . . . . plaster, . ointment, . . Vermifuge, . 1123 tea, . . . tonic, suppositories, 943 476 1152 476 653 265 225 394 992 1124 1125 1122 790 Vermilion, . . . 531 Vervain, fluid ext., 476 Veterinary liniment, 1098 ointment, . . . 1106 Viburnum, comp., 11 30 dentatum, fl. ext., 476 opulus, fl. ext., . 469 prunifolium, fluid extract, . . 467, 487 Viburnin, .... 733 Vichy water, solution, 871 Vienna draught paste, . . . yeast, . . . Vigor hair, . . Vin aromatique, . Vina, .... Vinegar, . aromatic, . . 5 bitters, . bloodroot, . cantharides, colchicum, . digitalis, lobelia, . opium, . rouge, . squill, . . . Vinegarettes, Vinegars. . toilet, . . . Vinous tincture c rhubarb, Vinum album album fortius, aloes, . . . antimoniale, . antimonii, . aromaticum, . aurantii, . . camphoratum, Chinas, . colchici radicis, colchici seminis, ergotas, . ferri, . . . ferri amarum, . ferri citratis, . ipecacuanha?, . opii, . . ■ . . oporto, . pepsini, . quinine, .... rhei rubrum, . . stibiatum, . xericum, Viola tricolor, fl. ext Violet, black ink, . extract, . extract, triple, 536 "95 49 3 1081 999 997 5i 1161 1043 54 52 52 53 53 53 "33 55 1 160 50 1161 936 997 997 998 999 998 999 999 1000 1000 1000 1001 IOOI IOOI 1002 1002 1003 1003 997 1004 1004 1005 1005 999 1005 476 252 1174 1156 1152 Violet ink perfumed, 1173 mouth water, . . 1140 oil 654 satchet, . . . .1159 syrup, . . . 828, 864 toilet powder, . .1136 water, . . .1158 Virgin oil, . . . 639 scammony. . . 729 Virginia creeper, fl. extract, . . 469, 473 Visceral elixir, Boer- have's, . . . 380 Hoffman's, . . 381 Viscum album, fl. ext., 476 Vitalized wine, . . 1012 Vitrified antimony, . 160 Vitriol elixir, . . 73 oil, 781 white, . . . 1015 Vittie-vayr tincture, 947 Vogler's acid elixir, 380 Volatile liniment, . 543 oils, ... . 642 Volumetric test so- lutions, . . . 584 Volumetric solution bi- chrom.of potas.,584 hypophos. of sod., 585 iodine, . . . 585 nitrate of silver, 585 oxalic acid, . . 585 soda, . . . . 585 Volumetric solutions, 584 Vulnerary spirit, . 772 w Wafer ash, fluid ex- tract, . . . 469, 4S7 Wahoo bark, fluid extract, . .469, 487 bitters 1038 elixir 325 extract 446 Walnut oil, . . . 662 hair oil, . . . 1142 Walrus oil, . . 642 Warburg's tincture, 951 Warming plaster, . 389 Warner's gout cordial, 936 Wash, black, . . . 596 Fuller's leg, . . 597 hair, .... 1084 yellow, .... 596 Washing crystal or powder, . . .1170 fluid, .... 1 169 precipitates, . . 44 Watchmaker's oil, . 639 Water of ammonia, 143 ammonia, stronger, 144 1283 468 4 62 Water of anise, . Apollinaris, barata, . . . bath percolation, bath percolator, bitter almond, camphor, . caraway, carbolic acid, . Carlsbad, . cherry laurel, . chloroform, chlorine, . . 2 cologne, Congress, . creasote, cinnamon, . dill distilled. . . elder flower, eryngo, fl. ext., fennel, . . . fennel, fl. ext., Florida, . . Friedricshall. . glass, . . . Hunyadi Janos, Javelle, . . 56 Ki^sc-ngen. lavender, . lead, . . lime, . . lime, stronger lithia, . . orange flower, pepper, fl. ext. ,46 peppermint, pimento, plantain oil, potash, . proof blacking, proof glue, . Pullna, . . Pyrmont, . . rose, . . Seltzer, . . Spa spearmint, tar, .... Vi< hy, . violet, . wintergreen, . Watermelon seed.fl Waters, med by distillation, eye by Kltration or per eolation, . by solution, mouth, . other, . . toilet, . . 40 164 B68 18S ,438 41 163 i6 S r66 165 686 16S 166 5. 552 770 868 167 166 164 167 171 .487 167 , 469 1158 869 567 869 7, 558 869 1158 5»4 551 397 560 164 5.487 169 170 654 565 11- ubs 870 870 170 870 870 i' 1 169 M-- 168 x-474 l6l [6l 1075 Wax. bay, bottle, . Carnauba, earth, emulsion, gilding, Japan, , laundry, mineral, modeling, moustache, myrtle, . ointment, palm, fluid paraffin, plaster, . sealing, varnish, white, . yellow, . Waxed paper Waxes, 216 216 4 o3 216 216 IIS2 216 2l6 "45 215 974 extract, 468 216 394 216 "93 215 214 232 214 767 [62 161 II40 '7' 1 [62 Weights and measures, 10 Weingist, Weingeist verdiinnter, 92 West India copal, Whale oil, soap, . Wheat whisky Whey, . . '. alum, Whisky, . . artificial, blends, . . bourbon, bourbon essence Irish, . . malt, . . rye, . . . rye essence, Scotch, . . wheat, . . White of egg, elixir, ink, . . . lead plaster, pine pitch, . syrup, comp tincture, 1064, 952 turpentine, 662, 694 Whiting, . Wickersheim's sol. 724 641 743 1189 542 138 11 89 11S9 1 1 89 1 189 1189 1 190 1 190 11S9 1 1 90 IIQO II89 83 367 "77 385 694 1064 precipitate, ointment, root, fluid extract tract, . vitriol, . . . wax, wine, artificial, stronger, wines, . Whitewood, fl, ext. 524 979 461 [156 M5 997 11-' ii- 162 206 11S4 Wickup, fl. ext., 474, 487 Wiener trank, . . 536 Wild cherry bitters, 439 extract, . . 439 elixir, . . . 376 compound. . 37 S detannated, . 376 ferrated, . . 377 fcrriphosphat'd.377 ferrophosphor- ated, . . 37S essence, . . . 434 extract, distilled, 452 fluid extract, . 478 fl. ext. comp., . 4S5 fl. ext., detannat, 481 infusion, . . 535 and iron wine, . 1013 syrup, . .810, 853 syrup, comp., . 1065 tar cough syrup, 1064 wine, . . . 1013 Wild ginger, ext. for perfumes, . .1154 oil 653 olive, extract, . .1156 indigo, . . 461, 487 lettuce, fl. ext., . 475 turnip, fl. ext., . 465 violet, fl. ext., . 476 yam, fl. ext., . . 461 Willow black, fl. ext., 469 herb, fl. ext., . . 474 white, fl. ext., . 469 Wine of aloes, . . 998 antimony, . . 998 antiscrobutic, . . 1014 aromatic, . 999, 1006 beef 1007 beef anil iron. . 1007 beef, iron and cin- chona, . . . 100S bitters, restorative, 1014 calisaya, . . . 1008 calisaya, iron and strychnine, . , toog camphor, . . . n*>o 1 inchona, . 1000, 1008 cinchona and iron. 1008 1 inchona, iron and strychnine, . . 1009 citrate ol iron, . 1002 coca i 1 "", colchicUm seed, 1001 colchicum root, . 1 color jvj 1 omfre] ip., , 1014 cotton root, , toio damiana, . . . toio ergot ion 1284 Wine erythroxylon, 2009 essences, or ext's, 1186 gentian compound, 1014 golden seal comp , 1014 gossypium, . . 1010 hellebore comp., 1014 high 88 ipecac, .... 1003 iron, . . 1001, 1010 iron, bitter, 1002, . . . . 1008, 1014 iron and pepsin, 1012 iron and wild ch'ry, 1013 malt, . . . . 613 oil of, heavy, . . 82 opium, .... 1003 orange, .... 999 pancreatin, . . 1011 pepsin, . . 104, ion pepsin and iron, 1012 prepared, . . . 1006 quinine, . . . 1004 red, . ... 1005 red, artificial, . .1186 rhubarb, . . . 1005 sherry, .... 1005 spirit of. . . . 88 spirit of, rectified, 88 syrups 864 tar 1012 tonic, bitter, . . 1014 Turneria, . . . ioro vitalized, . . . IOI2 white, artificial, . 1186 wild cherry, . . 1013 wild cherry and iron, .... 1013 Wines, . . 997, 1184 artificial, . . . 1186 of drugs, . . . 1014 improvement of, . n 85 and liquors, . . 1184 red 1185 white 1 185 Wintera or Winter's bark, fl. extract, 462 Wintergreeness., 415.767 extract, soluble, . 425 fluid extract, . . 474 oil, 648 syrup, . . . S64 syrup soda water, 425 water 168 Witch-hazel ext. dis. , 452 fluid extract, . 474, 478 Witherite, ... 187 Wizard balm, . . 1033 liniment, . . . 1095 Wolfram, .... 967 Wolfratnium, . . 967 Wood alcohol, 85, 86. 95 anemone, fl. ext., 473 Wood charcoal, . . 212 Woodchuck oil, . . 641 Wood naphtha, . 95, 772 naphtha, Hastings, 772 oil, .... 182, 663 soot ointment, . 992 spirit, .... 772 tea 758 Woods 22 Wool fat, . . .641, 968 Women's health re- storative, Working processes, Worm con. powder, killer, . . lozenges, . medicines, . powder, Wormseed oil, fluid extract, Worm syrup, syrup, standard, tablets, . . . tea, .... Wormwood essence, extract, . fluid extract, oil, . . . tincture, Writing fluid, 4" 1077 24 1058 1122 1 124 1122 721 647 , 462 1123 1123 1124 1125 416 443 473 653 881 1174 Xanthoxylin, . 732, 733 Xanthium strumari- um, fluid extract, 469 spinosum, fl. ext., 469 Xanthoxylum, bark, fluid extract, . 460 berries, fl. ext., . 462 Xylol 694 Xylene 180 Yam, wild, fl. ext., . 461 Yarrow, fl. extract, 473 oil 653 Yeast 498 Vienna, . . . 498 Yellow coloring, . 248 chrome, . . . 698 dock, fl. ext., .472, 484 dock syrup, comp., 829 ink, . . . 1 1 73 jasmine elixir, . 326 jasmine, fl. ext., . 460 jasmine tincture, . 909 lemon, .... 698 mercurial lotion, . 596 Yellow mercuric oxide, 528 oxide of mercury, 528 parilla, fl. extract, 465 root, fluid extract, 469 soap, .... 742 subsulphate of mer.,530 wash, .... 596 wax 214 Yerba buena, fl. ext., 462 mansa, fl. extract, 465 reuma, fl. ext., 474, 487 santa elixir, . . 378 elixir, compound, 379 fluid extract, 461, 4S7 glycerite, comp., 522 syrup, arom'c.829,830 syrup, comp., . 829 Ylang ylang essence, 1153 extract, . .1155 oil 653 sachet, . . .1159 Yolk of egg glycerite, 519 Youth, bloom of, . n 33 Zanthorrhiza, fl. ext. Zedoaria, or zedoary, fluid extract, tincture, Zedoary oil, . tincture, comp., . Zimmet syrup, . . Zinc, amyl bromide, carbonate, precip., chloride, . . . etherate, solution, cyanide, ethyl ferrocyanide, . granulated, . . iodide lactate, . . . ; methyl, .... ointment, . oleate, .... liquid, . . . ointment, . . oxide phosphide, potassium cyanide, salicylate, . sulphate, . . . sulphocarbo late, .... 782, tartrate, valerianate, elixir, 469 462 947 653 952 798 1015 102 1 1016 1016 1017 81 568 1020 1021 1021 1020 1018 1021 1021 991 659 659 991 1018 1018 1021 1021 1019 1019 1021 1020 376 ^^m M in ■ mm in ■ m m/'j':