1 a \l\ Oj \}t\ Jjlif5-fHMJm»l*?HSl . vO V*Y The New Standard Formulary Comprising in Part I all Preparations official or included in the Pharmacopeias, Dis- pensatories or Formularies of the World, together with a vast collection from other sources. The Parts following embracing Domestic and Veterinary Remedies, Proprietary and Synthetic Remedies, Perfumes and 1 oilet Articles, Soda and other Beverages and Domestic Utilities. BY A. EMIL HISS, PH. G. A*ND ALBERT E. EBERT, PH. M., PH. D. FIFTH REVISED EDITION BY E. D. IRVINE, PH. G. CHICAGO G. P. ENGELHARD & COMPANY 19 2 <* COPYRIGHT 1920 By G. P. ENGELHARD & COMPANY -2 1.920 ©CI.A597285 CONTENTS PAGES PART I PHARMACEUTICAL PREPARATIONS ... H Part II. Domestic and Veterinary Remedies . 545 Part III. Synthetic and Proprietary Preparations 659 Part IV. Perfumes and Toilet Articles ... 881 Part V. Soda Fountain Beverages . . ■ • 1023 Part VI. Domestic Utilities ...••• 1033 PREFACE The original Standard Formulary has been so extensively revised and greatly enlarged that the present edition is more than double the former size. The first part contains a vast collection of so-called pharma- ceutical or galenical preparations. It includes all the formulas of the United States Pharmacopoeia, the National Formulary, the Eclectic Dispensatory, the Homeopathic Pharmacopeia, the Cin- cinnati Academy of Pharmacy, the British Pharmacopeia, the British Formulary, the German Pharmacopeia, the Thomsonian preparations, Rademacher's preparations, and Kneipp's remedies ; also many from the Austrian Pharmacopeia, the German For- mulary, the Swedish, Danish and Norwegian Pharmacopeias, the French Codex, from formularies of several American hospitals, and of the London Throat Hospital ; also the best afforded by Hager's and Dietrich's manuals, as well as many other formulas which are considered practical and useful and have received the sanction of good authority. In this part are included formulas for articles of surgical use, such as medicated cottons, gauzes, ligatures, etc., also dermatic varnishes and pastes, and many of Unna's and Lassar's preparations. Part II includes the vast array of preparations for Domestic and Veterinary use which pharmacists are expected to keep put up ready for counter sale. Whatever information regarding dis- eased conditions is necessary to enable the pharmacist to make intelligent selections from the formulas here offered is also in- cluded. Part III includes the so-called Patent Medicines, the Phar- maceutical Preparations, and the Synthetic Remedies. These three classes, while not similar, frequently bear similar titles, and are for this reason more appropriately placed together than in separate divisions. The arrangement is entirely alphabetical. Part IV is a comprehensive treatise on Perfumes and Toilet Articles. A great deal of attention is paid to the chemistry of volatile oils, the isolated principles of these oils, and the various synthetics used in the manufacture of perfumery prod- ucts. As many reliable formulas as possible, mentioning these synthetics, for perfumery articles, are included. Part V contains a choice collection of formulas from the Manual of Soda and Other Beverages. Part VI includes all remaining formulas which will prove of service to the pharmacist, such as shoe blackings, inks, polishes, and everything else of whatsoever nature the druggist deals or wishes to know about. This part is therefore not the least useful of all. Whenever possible, the formulas in the different parts have been arranged in alphabetical order. A copious index is also provided. All information that has ever been furnished in the pamphlets and treatises by the various departments at Washington, par- ticularly the Department of Agriculture, has been utilized to the fullest possible extent in this book. A large amount of valuable information has been derived from this source. Attention is called to the completeness of the various intro- ductories to each primary topic. The quantities of all formulas have been adapted to the usual needs of retail pharmacists, these quantities being such even amounts as a pint, half-gallon, gallon, etc. Formulas taken from foreign sources have been recast so as to eliminate the weighing of liquids and to reduce or change the amounts to these even quantities. Owing to the greater familiarity of druggists in this country with the avoirdupois system of weights, troy weights and the metric system have been discarded. The reformed spelling has been adopted in designating chemical names, such as iodin for iodine, sulfur for sulphur, chlorid for chloride, sulfid for sulphide, etc. A. E. HISS. The above, written by Professor Hiss, one of the authors of the First Edition of the New Standard Formulary, applies equally to this, the Fifth Edition. The present edition has been revised to correspond with all Pharmacopoeias and Official Formularies, published since the date of the first edition. E. D. IRVINE. Part I. PHARMACEUTICAL PREPARATIONS Abstracts. These preparations were introduced into the United States Pharmacopeia of 1880, but were dropped from the edition of 1890. They are still used to some extent ; ,the following is a general proc- ess for their manufacture : Drug, No. 60 powder av.oz. 8 Menstruum, t Powdered sugar of milk, each.. sufficient Moisten the drug with menstruum, and pack, macerate, and extract in the usual way for making fluid extracts, re- serving the first 6^4 fluidounces of per- colate obtained and continuing percola- tion until the drug is exhausted. Evap- orate the second percolate, at a temper- ature not exceeding 50 degrees C, to 1% fluidounces; mix this with the re- serve percolate, place the whole in a broad evaporating dish or other suitable vessel; add 4 av. ounces of milk sugar, mix well, cover the vessel with a piece of thin muslin gauze to exclude dust, and set the whole aside in a warm place, where the temperature will not rise above 50 degrees C, until the mixture is dry. Then add enough milk sugar to make the whole weigh 4 av. ounces, re- duce the whole to a uniform fine pow- der, and keep in a well-stoppered bottle. Essentially, therefore, the process of manufacture consists in making a fluid extract, evaporating this to a dry solid extract, and adding enough milk sugar to make up a quantity of one-half of the weight of the original drug. Eleven abstracts were official, viz., aco- nite, belladonna (root), conium (fruit), digitalis, henbane (leaves), ignatia, ja- lap, nux vomica, podophyllum, senega and valerian. The menstruum usually employed in extracting the drugs was alcohol, the exceptions being nux vom- ica and ignatia, in which the menstruum was a mixture of alcohol and water in the proportion of eight of the former to one of the latter, and conium, in which the first four fluidounces of alcohol used as menstruum is mixed with three fluidrams of diluted hydrochloric acid. Abernethy's Remedies. Abernethy was a celebrated English physician who placed great reliance on the mercury treatment, his favorite pre- scription being a 5-grain blue mass pill at night, to be followed by 1 to 1^ fluidounces of black draught (compound infusion of senna). The composition of the pill was changed subsequently but was finally settled at 3 gr. of blue mass with 2 gr. of compound extract of colocynth. This is what should be given when Aber- nethy's pills are demanded, although sometimes a 5-gr. pill composed of 2 parts of compound extract of colocynth and 1 part of blue mass is used. This is also used as Abernethy's pill: Socotrine aloes gr. 2 Extract of henbane gr. 2 Blue mass gr. 1 Ipecac gr. 5/6 Acid, Acetic, Diluted. Acetic acid » . . . av.oz. 1 Distilled water av.oz. 5 Both ingredients are to be weighed. The acid employed should be of the U. S. P. strength, viz., 36 per cent, of absolute acid. A weaker acid may be used as well as a stronger one, in the one case using less water for dilution, in the other more, so that the product contains 6 per cent, of absolute acid. — U. S. P. Acid, Carbolic, Liquefied. Liquefy the acid by placing the un- stoppered container in a water bath and heat gradually until the crystals are 12 STANDARD FORMULARY OF melted ; transfer the liquid to a tared vessel and weigh, and to every 9 parts by weight add one part of distilled wa- ter, and mix thoroughly.— U. S. P. The liquefied acid of the Germ. Pharm. differs from this only in being made from 10 parts of acid to one part of water. Acid, Carbolic, No. 33. This is a dilution of carbolic acid recommended by the Cleveland Phar- maceutical Association as more conveni- ent and safe to use than liquefied car- bolic acid, i.e., crystal carbolic acid melted and maintained in a liquid state by the addition of 5 per cent, of water, alcohol, or glycerin. It was directed to be prepared as follows : Carbolic acid, crystal. . av.oz. 2 or fl.oz. 2 Glycerin av.oz. 5 or fl.oz. 4 Melt the acid and add the glycerin. This No. S3 acid mixes readily with water in all proportions, and, not being as caustic as the ordinary liquefied acid, cannot result in as much mischief or fatality if used improperly, or if taken accidentally or purposely. In Chicago the sale of a 33 1/3 per cent, acid consisting of equal parts of liquefied carbolic acid, alcohol and gly- cerin is permitted by a city ordinance. Acid, Carbolic, Camphorated. (Phe- nol Camphor. — Carbolized Cam- phor. — Camphorated Phenol.) Camphor, coarse powder, .av.oz. 10 Carbolic acid, crystal av.oz. 3 l / 2 Alcohol fl.oz. y 2 Triturate together until an oily liquid is obtained, or mix in a bottle and agi- tate frequently until solution occurs. Acid, Carbolic, Iodized. (Phenol Iodatum. — Idoized Phenol.) Iodin, reduced to powder, .av.oz. 1 Glycerin av.oz. 3 Carbolic acid av.oz. 1 Put the iodin into a flask, add the acid, previously melted, then the gly- cerin, and digest the mixture at a gentle heat, frequently agitating, until the iodin is dissolved. Keep the product in glass-stoppered vials, in a dark place. The above is used as a local applica- tion in uterine and skin diseases. A modified form is the so-called carbolate of iodin inhalant. — N. F. Acid, Hydrobromic, Diluted. This preparation is recognized by the U. S. P. which, however, gives no proc- ess for it. It may be prepared as fol- lows : Potassium bromid av.oz. 3 Tartaric acid av.oz. 2>Va Distilled water fl.oz. 16 Dissolve the salt and acid each sepa- rately in 8 fluidounces of water, then mix the solutions, put the mixture in a cold place, preferably on ice, for about 12 hours, then decant the clear liquid, and filter it. The product contains 10 per cent, of absolute hydrobromic acid. There is also some cream of tartar which is unob- jectionable in most instances but at times may interfere with its usefulness. A superior product is obtained by Squibb's process, the mixing of solution of potassium bromid and sulfuric acid, allowing the potassium sulfate to cry- stallize out, and then distilling. The product should be kept in glass- stoppered bottles, protected from light Acid, Hydrochloric, Diluted. (Dilu- ted Muriatic Acid.) Hydrochloric acid fl.oz. 4^ Distilled water fl.oz. 11^2 Or mix in the proportion of 5 av. ounces and 11 av.ounces. — U. S. P. Keep in glass-stoppered bottles. The acid used for the above should be a c. p. article corresponding in strength to the U. S. P. If weaker, more of it or proportionately less water should be employed. The diluted acid should contain 10 per cent, by weight of absolute acid. Acid, Hydrocyanic, Diluted. (Prus- sic Acid.) I. The U. S. P. VIII states that it may be prepared extemporaneously as follow*: PHARMACEUTICAL PREPARATIONS. 13 Silver cyanid gr. 54 Diluted hydrochloric acid. . .fl.dr. 2^ Distilled water fl.dr. 7 Mix the acid and water, add the silver cyanid and shake the whole together in a glass-stoppered bottle. When the pre- cipitate has subsided, pour off the clear liquid. The product contains not less than 2 per cent, by weight of absolute acid. U. S. P. IX gives no process but gives the strength as 1.9% to 2.1%. This preparation should be kept in small, dark amber-colored, cork-stopper- ed bottles in a cool place. The U. S. P. 1890 gave another more elaborate process for this preparation, which is here given. II. Potassium ferrocyanid, coarse powder gr. 300 Sulfuric acid fl.dr. 2 Water fl.dr. 17 Distilled water, sufficient. Place the potassium salt in a tubulated retort and add to it 10 fluidrams of water. Connect the neck of the retort (which is to be directed upward) by means of a bent tube with a well-cooled condenser, the delivery tube of which terminates in a receiver, surrounded by ice-cold water, containing 17 fluidrams of distilled water. All the joints of the apparatus, with exception of the neck of the receiver, having been made air- tight by means of well-fitting corks, pour into the retort through the tubu- lure the sulfuric acid previously di- luted with 6]/ 2 fluidrams of water. Gent- ly mix the contents of the retort, and then heat it in a sand bath so as to keep the liquid in brisk ebullition until about one-half of its volume has passed into the receiver. Detach the receiver and assay a small portion of the contents by the method given below. Then add to the remainder so much distilled water as may be required to bring the product to the strength of 2 per cent, by weight of absolute acid. The sulfuric acid used must be of U. S. P. quality, i. e., of 98 per cent, strength, free from arsenic, etc. If weaker than 98 per cent., more of it must be used and correspondingly less water. The assay process for the above is as follows: Mix in a flask, about 100 c. c. capacity, 0.27 gm. of the distillate with sufficient distilled water and light mag- nesia to make an opaque mixture of about 10 c. c. Add to this 2 or 3 drops of potassium chromate test solution U. S. P., and then from a burette silver nitrate decinormal volumetric solution until a red tint is produced which does not again disappear on shaking. Each c. c. of silver solution used indicates 1 per cent of absolute hydrocyanic acid. Acid, Hydrocyanic, Scheele's. This is to be prepared from potassium ferrocyanid and sulfuric acid according to the process of the U. S. P., but in- creasing the quantity of the ingredients . proportionately. It should contain 4 per - cent, of absolute hydrocyanic acid. — Brit. Form. Acid, Hydrofluoric, Diluted. This is to contain 1/5 per cent, of ab- solute hydrofluoric acid. — Brit. Form. Acid, Hypophosphorous. According to the U. S. P., this con- tains 30 to 32% by weight of absolute hypophosphorous acid and 70 per cent, of water. The U. S. P. gives no process for making it but one is given by the N. F. Ill and the Brit. Form., both of which are here given : I. Potassium hypophosphite. .av.oz. 9 Tartaric acid av.oz. 12^4 Diluted alcohol. Distilled water, each, sufficient. Dissolve the potassium salt in 9 fluid- ounces ,of water, previously warmed and the tartaric acid in 17 fluidounces of diluted alcohol. Mix the solutions in a flask of sufficient capacity to permit agitation, cork and shake well, and set the flask in a bath, of ice water for 12 1 1 STANDARD FORMULARY OF hours. Then carefully pour the mixture into a funnel, the neck of which has been closed with a pledget of cotton, and when all the liquid has drained off, rinse the flask and wash the crystalline precipitate in the funnel with small por- tions of cold diluted alcohol unitl the washings no longer respond to the tests for hypophosphorous acid (black precip- itate with silver nitrate or white precipi- tate with mercuric chlorid). Mix the original filtrate and the washings, and evaporate the whole on a water bath at a temperature not exceeding 60 degrees C. until all the alcohol has been dissi- pated. Allow the liquid to cool and add enough distilled water to make the prod- uct weigh 18 av. ounces. This meas- ures about 16 fluidounces. It should be preserved in well-stop- pered bottles. II. Barium hypophosphite, contain- ing not less than 95 p. c. Ba. (H 2 P 2 ) 2 av.oz. 8 Diluted sulfuric acid, Distilled water, each, sufficient. Dissolve the barium salt in 36 fluid- ounces of hot distilled water, add 22^/^, fluidounces of diluted sulfuric acid, after which continue the addition of more acid, drop by drop, until no furth- er turbidity is produced. Set aside in a warm place and filter the clear liquid. Wash the precipitate by decantation with successive portions of water until the washings are no longer acid, filter, unite the filtrates, and evaporate the combined liquid on a water bath until it has the sp. gr. of 1.1367. — Brit. Form. The product will weigh about 11^2 av. ounces, and contain 30 per cent, of absolute acid. Acid, Hypophosphorous, Diluted. According to the U. S. P. this prep- aration contains 9.5 to 10.5% by weight of absolute hypophosphorous acid and is directed to be made by maxing 1 part by weight of the 30 per cent, acid with 2 parts of distilled water. Acid, Metaphosphoric, Diluted. (Di- luted Glacial Phosphoric Acid.) Phosphoric acid, glacial gr. 365 Distilled water, to make. . .fl.oz. 8 Dissolve the acid in the water, with- out heat. This preparation should be kept in a cool ancl dark place, and should not be prepared in larger quantity than may be consumed within a few months. The resulting product contains about 10 per cent, of metaphosphoric acid, provided the glacial acid was free from impurities. That which is sold in form of glassy lumps is usually of sufficient purity. The variety in form of round sticks is more or less impure, containing generally more than 15 per cent, of sodium phosphate. If this variety is alone available, a proportionately larger quantity must be taken, to be determin- ed, if time permits, by an assay of the free acid present. If no special accur- acy is required, about 420 grains of this variety of the acid may be reckoned to be equivalent to the quantity directed in the above given formula. Whenever iron pyrophosphate (U. S. P. or scale) forms one of the ingredi- ents of a mixture containing diluted phosphoric acid, the official tribasic acid is unsuitable, as it produces with the salt a gelatinous precipitate. If a clear mixture is required, the above prepara- tion is to be used in place of the official. The same may be done when iron phos- phate (U. S. P. or scale) is prescribed, though the precipitate caused by the offi- cial acid in this case is not as bulky, and under certain conditions may not form at all. It must also be remembered, however, that the glacial acid is itself incompatible with certain other sub- stances.— N. F. III. Acid, Nitric, Diluted. Nitric acid fl.oz. i l / 2 Distilled water fl.oz. 12^2 Or mix in the proportion of 2 l / 2 av. ounces and 14H av. ounces. Keep in dark amber-colored glass- stoppered bottles. PHARMACEUTICAL PREPARATIONS. 15 The acid should be of U. S. P. quality and strength; if weaker, more should be employed and correspondingly less water. The product should contain 10 per cent, by weight of absolute acid. — U. S. P. VIII. Acid, Nitrohydrochloric. (Nitromu- riatic Acid. — Aqua Regia.) Nitric acid, U. S. P fl.dr. 3 Hydrochloric acid, U. S. P. fl.dr. 13^ Mix the acids in a capacious glass vessel and, when effervescence has ceas- ed, transfer the product to dark amber- colored, glass-stoppered bottles which should not be more than half filled and keep them in a cool place. — U. S. P. Acid,, Nitrohydrochloric, Diluted. (Diluted Nitromuriatic Acid.) Nitric acid fl.dr. 5% Hydrochloric acid fl.oz. 3 Distilled water fl.oz. 13 Mix the acids in a capacious glass vessel and, when effervescence has ceas- ed, add the water. Keep the product in dark amber-colored, glass-stoppered bot- tles in a cool place. — U. S. P. The acids should be of the U. S. P. quality and strength, viz., nitric acid 68 per cent, of absolute acid and the hydro- chloric acid 31.9 per cent. If somewhat weaker acids be at hand, more must be employed and a proportionately smaller amount of water. Acid, Phosphoric, Diluted. Phosphoric acid fl.dr. 9 v'Vater, distilled fl.oz. 14^2 Or mix in the proportion of 2 av. ounces and 15 av. ounces. Keep in well-stoppered bottles. The phosphoric acid of the U. S. P. contains 85 per cent, of absolute acid. If a weaker acid be employed, more of it must be used, and correspondingly less water. A 50 per cent, acid is quite common; this may be used in the pro- portion of 2 fluidounces of acid and io^4 fluidounces of water, or 1 av. ounce and 4 av. ounces. The diluted acid should contain 9.5 to 10.5% of absolute acid.— U. S. P. Acid, Sulfuric, Aromatic. (Elixir of Vitriol. — Tinctura Aroma tica Acida.) Sulfuric acid fl.dr. 14 Tincture of ginger fl.dr. &/i Oil of cinnamon, m. 8 or about drops 12 Alcohol to make fl.oz. 16 Add the sulfuric acid gradually 'and with great caution to 11^2 fluidounces of alcohol and allow the mixture to cool. Then add to it the tincture and oil and then enough alcohol to make 16 fluidounces. — U. S. P. Preserve in glass-stoppered bottles. The product contains 20 per cent, of absolute acid by weight providing fuli strength acid, 92^ per cent., was used in making it. The preparation of the Brit. Pharm. contains about 15 per cent, of absolute acid, that of the 1st Germ. Pharm. (not mentioned in later editions) contained about 4 per cent, of absolute acid. Acid, Sulfurous. Sulfuric acid fl.oz. 2 Wood charcoal, coarse powder .. • : gr. 300 Distilled water fl.oz. 16 Introduce the charcoal into a glass flask having a capacity of about 16 fluid- ounces, add the acid, and mix well. Connect the flask by means of bent glass tubing, about 20 inches long, with a wash bottle having a capacity of about 8 fluidounces, containing about 2 fluid- ounces of water, so that the end of the inlet tube shall be below the surface of the water. Through the triply perfor- ated rubber stopper of the wash bottle pass a safety tube, which should reach nearly to the bottom of the bottle, and connect the latter by means of glass tub- ing with a bottle provided with a doubly perforated rubber stopper, having a capacity of about 32 fluidounces and con- taining 16 fluidounces of well-cooled distilled water. The inlet tube should dip about 1 inch below the surface of the distilled water. By means of a second tube connect this bottle with an- other containing water, the end of the 16 STANDARD FORMULARY OF tube extending 2 inches below the sur- face of the water. Having ascertained that all the connections are air-tight, apply a moderate heat to the flask con- taining the acid and charcoal, until the evolution of gas has nearly ceased, and during the passage of the gas, keep the bottle containing the distilled water at or below 10 degrees C. by surrounding it with cold water or ice. Assay a small portion of the sulfurous acid by the method given below. Then add to the remainder enough distilled water to bring the product to the strength of 6.4 per cent by weight of sulfur dioxid. Finally pour the sulfurous acid into dark amber-colored, glass-stoppered bot- tles which should be compeltely filled, and kept in a cool place, protected from light.— U. S. P. VIII. Owing to its rapid deterioration, sul- furous acid should be frequently assay- ed, and none should be dispensed if it fails to conform to the assay given be- low. The wash bottle retains the sulfuric acid which is carried over mechanically, also some of the sulfur dioxid, while the distilled water in the receiving bot- tle becomes a saturated solution of the sulfur dioxid, probably containing also some carbon dioxid. The sulfuric acid used for this prep- aration should be chemically pure but need not be U. S. P. strength, as low as a 75 per cent, acid serving the pur- pose but somewhat more of it should be employed. This preparation may also be made by heating together metallic copper with sulfuric acid, copper sulfate and sulfur dioxid being formed. The U. S. P. describes the prepara- tion as an aqueous solution containing not less than 6 per cent, by weight of sulfur dioxid, but the strength men- tioned in the assay is 6.4 per cent. Assay Process : Introduce into a stoppered weighing-bottle 2 c. c. of sul- furous acid and weigh accurately. To this add .so c. c. tenth-normal volumetric solution of iodin and allow it to stand for 5 minutes, then slowly add tenth- normal volumetric solution, of sodium thiosulfate until the mixture is just de- colorized. Subtract the number of c. c. of the sodium thiosulfate solution used from 50, and mulitply the difference by 0.318 and divide this product by the weight of the acid taken : the quotient represents the percentage of absolute sulfurous acid in the latter. Alcohol. Alcohol, meaning thereby ethyl alco- hol, is used in different strengths, some of these strengths having received spe- cific titles and are recognized authorita- tively. Alcohol (U. S. P.).— This contains 92.3 per cent, by weight or 94.9 per cent, by volume of absolute alcohol and has a specific gravity at 60 degrees F. of 0.816 or at J7 degrees F. of 0.809. Diluted Alcohol (U. S. P.).— This may be made by mixing equal volumes of alcohol and distilled water, or by mixing the alcohol and water in the proportions of 41 and 50 by weight. The product contains about 41.5 per cent, by weight or about 48.9 per cent, by volume of absolute alcohol, the apparent discrepancy in strength being due to contraction in volume which oc- curs when alcohol and water are mixed, 20 volumes of alcohol mixed with the same measure of water forming but about 39 volumes of mixture. Absolute Alcohol (U. S. P. and Brit. Pharm.). — This should contain at least 99 per cent, by weight of absolute alco- hol (about 99.4 per cent, by volume). Ordinary alcohol may be made strong- er by macerating it with dried copper sulfate and filtering, or by macerating with freshly-burnt lime for 24 hours, decanting the liquid, and distilling off about three-fourths of the latter. Deodorized Alcohol (U. S. P. 1800). — This differed from ordinary alcohol in being somewhat stronger (92^2 per cent, by weight or 95.1 per cent by PHARMACEUTICAL PREPARATIONS. 17 volume of absolute alcohol) and in hav- ing been deprived of certain foreign constituents contained in the latter. The commercial "cologne spirits" is a de- odorized alcohol but is usually not up to the requirements of the U. S. P. Alcohol of the present pharmacopeia is practically equal to the deodorized alcohol of the U. S. P. 1890. Many methods for deodorizing alcohol have been recommended, but the follow- ing will be found satisfactory: A convenient amount of alcohol is shaken with powdered potassium per- manganate until it assumes a decided color. Then allow to stand for several hours until the permanganate has be- come decomposed, and brown man- ganese dioxid has deposited. A small amount, say V\ ounce, of pulverized calcium carbonate should then be added, and the whole subjected to distillation, using a well-cooled receiver. Distil very slowly at first, testing the distillate frequently, until a mixture of the dis- tillate and a strong (syrupy) solution of pure caustic soda or potassa, in the pro- portion of 10 of the former to 1 of the latter, gives no perceptible yellow color- ation even on standing for 20 minutes or half an hour. The first portion of distillate that yields this coloration should be rejected; the last one-eighth of liquid should not be distilled, and should also be rejected. The remaining portion only is adapted for use. This alcohol is adapted to all chemical purposes and for use in the manufac- ture of perfumes. Alcohol or Alcohol Fortius or Strong Alcohol (Homeopathic) is the same as alcohol (U. S. P.). Whenever the term alcohol is used in homeopathic phar- macy, this kind of alcohol is under- stood. It is used in the preparation of tinctures. The so-called "homeopathic alcohol" is a good grade of this kind of alcohol, such as sold under the name "cologne spirits." Officinal or Dispensing Alcohol or Al- cohol Officinale (Homeopathic) con- tains 83 per cent, by weight or 88 per cent, by volume of absolute alcohol and has a sp. gr. of 0.840 at 60 degrees C. It may be prepared by adding 1 volume of distilled water to 11 24 volumes of alcohol or 1 part by weight of distilled water to 9.64 parts by weight of alcohol. It is used for making dilutions from tinctures because this degree of strength is more readily absorbed by both cane and milk sugars. Proof Spirit, Brit. Pharm. (spiritus tenuior) is slightly stronger than diluted alcohol U. S. P., containing about 49 per cent, by weight or about 57 per cent. by volume of absolute alcohol. Alcohol, Dehydrated, U. S. P., con- tains not less than 99% by weight of absolute alcohol. Alcoolats. These are a class of French prepara- tions produced by distillation of drugs with alcohol. Balsamum (or baume de) fioravanti is an example. Alcoolatures. A class of French preparations pro- duced by the action of alcohol upon fresh plant parts. They correspond to the tinctures of fresh herbs of our phar- macopeia. Alcooles. Alcoole is a name sometimes applied in French to alcoholic tinctures of dry drugs. Aloes, Purified. Socotrine aloes av.oz. 16 Alcohol ' fl.oz. Z l A Heat the aloes by means of a water bath until it is completely melted, then add the alcohol and, having stirred the mixture thoroughly, strain it through a No. 60 sieve which has just been dipped into boiling water. Evaporate the strained mixture by means of a water bath, constantly stirring, until a thread of the mass becomes brittle on cooling. Then allow to cool, break the product into pieces of convenient size, and keep in well-stoppered bottles. 18 STANDARD FORMULARY OF This process removes mechanical im- purities from the aloes, such as frag- ments of wood, earthy matter, etc. Alum, Porous. This is prepared by evaporating the saturated solution of alum, freed from iron, and just before it is upon the point of crystallizing adding about 1/5 of 1 per cent, of sodium bicarbonate. The carbonic acid gas produced, when expelled by the heat, renders the mass porous. Alum, Exsiccated or Dried. (Burnt Alum.) Alum, small pieces. av.oz. 20 Place in a shallow porcelain capsule so as to form a thin layer and heat it on a sand bath until it liquefies. Then continue the application of a moderate heat with constant stirring until aqueous vapor ceases to be evolved and a dry, white, porous mass is obtained weighing 11 av. ounces. When cold, reduce to f:ne powder. — U. S. P. It should be preserved in well-closed containers. Potassa alum, not ammonia alum, should be used to make the dried article. Antimony Sulfid, Purified. Antimony sulfid av.oz. 8 Ammonia water fl.oz. 4 Water, sufficient. Reduce the antimony sulfid to very fine powder if not already in powder. Separate the coarse particles by elutria- tion and when the finely divided sulfid has deposited, pour off the water, add the ammonia water, and macerate for 5 days agitating the mixture frequently. Then let the powder settle, pour off the ammonia water, and wash the residue by repeated affusion and decantation of water. Finally dry the product by the aid of a gentle heat. This process removes copper and ar- senic sulfids and other impurities. The antimony sulfid must not be the ordinary commercial variety, as it is usually adulterated with coal dust. — U. S. P. 1890. Arquebusade. (Brown Arquebusade. — Wund Wasser. — Mistura Vul- neraria Acida. — Aqua Vulneraria Thedeni.) Acetic acid, diluted fl.oz. 8}4 Alcohol fl.oz. zV\ Water fl.oz. 1 Sulfuric acid, diluted fl.oz. 1% Clarified honey fl.oz. 2 Mix and filter. — H. and D. Arquebusade, White. (Aqua Vulner- aria Spirituosa or Vinosa.) Oil of sage drops 7 Oil of wormwood.-. drops 7 Oil of rue drops 7 Oil of peppermint drops 7 Oil of rosemary drops 7 Oil of marjoram drops 7 Oil of lavender flowers. .. .drops 7 Alcohol fl.oz. 19 Water fl.oz. 13 Dissolve the oils in the alcohol and then add the water. — H. Balm of Gilead, Factitious. (Arti- ficial Balsam of Mecca.) The original is an oleoresin derived from a tree growing on the shores of the Red Sea. Imitations are much more common and are prepared as stated be- low: I. Benzoin, coarse powder av.oz. 2 Liquid storax av.oz. i l /i Tolu balsam av.oz. 1 Balsam of fir av.oz. 12 Place in a glass flask or bottle, and subject to the heat of a water bath for several hours; agitate frequently until liquefied : allow to cool, and decant the clear portion, to which add sufficient of the oils of lemon, cassia, rosemary, and nutmeg and vanilla extract to give it a strong aromatic odor. II. Benzoin, coarse powder. . .av.oz. 1 Peru balsam av.oz. 1 Vanilla, cut small gr. 60 Nutmeg, broken gr. 60 Balsam of fir av.oz. 8 Digest the whole as above, decant, and to decanted liquid add same essen- tial oil? as in I. PHARMACEUTICAL PREPARATIONS. 19 Balm, Parturient. Blue cohosh — av.oz. I Spikenard av.oz. i Black cohosh av.oz. y 2 Mitchella av.oz. y 2 Queen-of-the-meadow root. av.oz. y 2 Ladies' slipper root av.oz. l /^. Comf rey av.oz. ^4 Sugar av.oz. 10 Alcohol, water, each to make fl.oz. 16 Mix the drugs, reduce to moderately coarse powder, and extract in the usual manner with a mixture of i volume of alcohol and 2 of water so as to obtain 10 fluidounces and in the latter dissolve the sugar by agitation, strain, and add simple syrup if necessary to make 16 fluidounces of percolate. — Eclectic modi- fied. Balsam Fioravanti. (Baume de Fi- oravanti. — Spiritus Balsamicus.) Peru balsam drops 15 Rectified oil of turpentine. drops 15 Oil of cassia drops 15 Oil of clove drops 15 Oil of juniper berries drops 15 Oil of mace drops 15 Oil of thyme (white) drops 15 Alcohol to make fl.oz. 16 This is a simpler and more rational formula than that of the Codex, which requires distillation. — H. Balsam, Friar's. (Traumatic, Wound, Vervain's, St. Victor's, Turling- ton's, Persian, Swedish, Com- mander's, or Wade's Balsam. — Jesuit's Drops. — Traumatic Elix- ir.) Benzoin, coarse powder gr. 720 Storax gr. 240 Tolu balsam gr. 240 Peru balsam gr. 120 Aloes, coarse powder gr. 60 Myrrh, coarse powder gr. 60 Angelica root, moderately coarse powder gr. 30 Alcohol fl.oz. 16 Macerate the substances with the alco- hol during 10 days, frequently agitat- ing, then filter. The above is lilce the formula adopted by the Philadelphia College of Phar- macy, the latter containing in addition 240 grains of extract of licorice. The official compound tincture of ben- 2 zoin is a simplified preparation intended to replace the above compound, and is in fact usually dispensed for it. See Tincture of Benzoin, Compound. Balsam of Honey. (Pectoral Bal- sam.) Turmeric, powder gr. 40 Opium, powder gr. 80 Tolu balsam av.oz. t y 2 Honey av.oz. 3^ Alcohol fl.oz. 12 Mix, macerate for 7 days, and filter. This preparation is also made without opium. This is used for coughs, hoarseness, etc. It must be used cautiously on ac- count of the opium present. The dose is 20 to 40 drops. — Cooley. Balsam, Locatelli. (Wund Balsam.) Venice turpentine av.oz. 2^2 Yellow wax av.oz. 3 Olive oil av.oz. 4 Peru balsam av.oz. J / 2 Alkannin gr. 10 Melt the wax, add the other ingredi- ents, and stir until solidified. This is used for chilblains, sore nip- ples, etc. — H.'s Revised Praxis. Balsam, Malta. (Balsam de Maltha.) This makes a preparation known by this name: Benzoin, powder av.oz. i^4 Peru balsam av.oz. 1 Aloes gr. 120 Alcohol fl,.oz. 16 Macerate for 7 days and filter. Balsam, Metz's. Olive oil av.oz. 6 Linseed oil av.oz. 6 Oil of laurel berries, ex- pressed av.oz. 1 Gum of turpentine av.oz. 2 Verdigris, powder gr. 180 Aloes, powder gr. 150 Zinc sulfate, powder gr. 75 Oil of juniper wood fl.dr. 3 Oil of clove fl.dr. 1 Mix the linseed and olive oils and gum by gentle heat, transfer to a bottle and incorporate the powders and other oils. Used as a dressing to wounds, ulcers, boils, etc. — H. 20 STANDARD FORMULARY OF Balsam, Nutmeg. (Balsamum Nucis- tae. — Muskat Balsam. — Magen Balsam. — Nutmeg Cerate.) Yellow wax av.oz. i Olive oil av.oz. 2 Expressed oil of nutmeg. . .av.oz. 6 Melt the wax and add the oils. — Germ. Pharm. II. A cheaper preparation can be prepared according to the following formula : Olive oil fl.oz. 6 Yellow wax av.oz. 2 Spermaceti gr. 130 Expressed oil of nutmeg, .av.oz. 7^ Alkanet gr. 5 Annatto gr. 15 Alcohol fl.dr. 2 Melt the wax and spermaceti, add the oil, divide it into two parts ; in one portion, digest the alkanet for 5 min- utes, add the nutmeg oil and strain ; triturate the annatto with the alcohol, digest the mixture with the second por- tion of oily liquid for 5 minutes, strain, add this to the first colature, mix well, and pour into molds if desired. Of course, a cheaper preparation may be produced by using a cheaper oil than olive oil, such as cottonseed or benne oil. — D modified. This is used as a warming application to the abdomen in bowel complaints of infants. Balsam, Riga, Factitious. The genuine, which is derived from a tree grown in northern Europe and Asia, is scarcely ever seen in this coun- try, and the following mixtures are used as imitations : I. Aromatic water fl.oz. 14 Spirit of sage (1 of oil to 49 of alcohol) fl.oz. i l /i Tincture of Spanish saffron. fl.dr. 3 Oleobalsamic mixture might be sub- stituted for the aromatic water. — H. modified. II. Oil of juniper wood fl.oz. 2 Compound tincture of ben- zoin fl.oz. 2 Alcohol fl.oz. 12 The genuine balsam is recommended for all kinds of ailments, internal and external, e. g., for colds, indigestion, sea- sickness, bruises, toothache, etc. Balsam of Sulfur. (Sulfurated Oil.) I. Linseed oil av.oz. 12 Sublimed sulfur, washed and dried perfectly av.oz. 2 Boil together in an iron vessel, stir- ring constantly, until a uniform liquid is obtained, being cautious in regulating the heat so that the liquid will not boil over. — H. II. The directions of the old Edinburgh Pharmacopeia were to gently boil 8 parts of olive oil and 1 part of sub- limed sulfur, in a large iron pot, stir- ring constantly until united. The pot should be large enough to hold three times the quantity of material operated upon, as otherwise the mixture might boil over. As the vapors which are given off are liable to take fire, a lid should be near at hand, so as to place over the pot and extinguish the flames. Undoubtedly other oils, such as cot- tonseed oil, could be employed for mak- ing this preparation. — H. Balsam of Turpentine. This preparation is known by this name : Olive oil fl.oz. 6 Oil of turpentine fl.oz. 2 Yellow wax av.oz. 1 Peru balsam fl.dr. 2 Camphor gr. 120 Essential oil of nutmeg. .. .fl.dr. 2 Melt the wax, add the olive oil, and then incorporate the other ingredients. Balsam, Universal. Liniment of camphor fl.oz. 2 Cottonseed oil fl.oz. 2 Yellow wax av.oz. 2 Infused oil of henbane fl.oz. 8 Solution of lead subacetate. .fl.oz. iy 2 Melt the wax, add the oils, allow to cool, and when fairly cool, thoroughly incorporate the lead solution with the mixture. — D. Under the above title, many kinds of preparations are offered, but the for- mula given is believed to be the most sensible and will furnish as good a product as any. PHARMACEUTICAL PREPARATIONS. 21 Bandages, Plaster of Paris. These are made by taking gauze of suitable kind and of the width desired, and rolling it up just as in making roller bandages, and while doing so, sprinkling over it freshly burned plaster of Paris sufficient to fill the pores. The band- age is then to be wrapped in waxed paper and put into a tin box, or it is put directly into the box, which latter should then be well closed. — D. Benzin, Petroleum, Purified. Potassium permanganate. . .av.oz. 1^4 Sodium hydroxid av.oz. J4 Sulfuric acid fl.oz. 8 Petroleum benzin gall, i Water, sufficient. Add the acid to 70 fluidounces of water and when the mixture has become cold, pour it into a bottle having the capacity of about 2 gallons. Add 1 av. ounce of potassium permanganate and agitate until it is dissolved, then add the benzin in four portions, shaking the liquid after each addition. Allow the liquids to remain in contact for 24 hours, shaking the bottle at frequent in- tervals ; then decant the benzin into an- other bottle of the same capacity, and having dissolved Va av. ounce of potas- sium permanganate in 32 fluidounces of water, in which the caustic soda has previously been dissolved, mix the liquids and agitate the mixture frequent- ly during several haurs, then decant, re- peat the washing with water, and again decant the purified benzin. — U. S. P. Bismuth Oxid, Hydrated. Bismuth subnitrate av.oz. 6 Nitric acid av.oz. 10 or fl.oz. 7 Ammonia water. . . av.oz. 12 or fl.oz. 12 Sodium bicarbonate. . .'. . .av.oz. 1 Distilled water, sufficient. Mix the bismuth subnitrate with 4 fluidounces of distilled water in a quart flask, add 9 av. ounces (or about 6]4 fluidounces) of nitric acid, and promote the solution of the salt by agitation, and, if necessary, by a gentle heat. Pour the solution into 1 gallon of distilled water previously acidulated with 1 av. ounce of nitric acid, and filter the liquid through absorbent cotton. Mix the am- monia water with 2 gallons of distilled water in a glazed vessel of double that capacity, and pour into it, slowly and with constant stirring, the bismuth solu- tion. Let the mixture stand during 4 hours so that the precipitate may sub- side, then pour off the supernatant liquid, and wash the precipitate 4 times more by decantation with distilled water, the sodium bicarbonate being dis- solved in the last wash-water. Pour the precipitate upon a wetted muslin strainer, and wash it with distilled water, until the washings run off taste- less. Transfer the strainer to a warm place, so that the precipitate may dry. Then rub the latter to powder, and keep it in well-stoppered bottles. The nitric acid and the ammonia water used for the above should be of U. S. P. strength, the former 68 per cent., the latter 10 per cent. If the am- monia water be weaker or stronger than 10 per cent., correspondingly more or less of it must be employed. Hydrated oxid of bismuth is some- times demanded in the form of a creamy mixture with water, under the name of Cremor Bismuthi or Cream of Bismuth. This may be prepared by triturating 20 parts of the oxid with 80 parts of water. — N. F. III. Bitters, Astringent. Bayberry lb. 2 Golden seal lb. 1 Ginger lb. 1 Capsicum -. oz. 2 Clove oz. 2 All in fine powder; mix well. — Thom- sonian (from the Guide and the Ma- teria Medica). Bitters, Restorative and Relaxing. Ox gall pint 1 Holland gin pints 4 Molasses pints 4 — Thomsonian (from the Guide and the Materia Medica). STANDARD FORMULARY OF Bitters, Spice. I. Thomsonian (from the Guide and the Materia Medica). Poplar bark lb. I Balmony oz. 7 Bayberry oz. 4 Ginger oz. 4 Clove oz. 3 Golden seal oz. 3 Capsicum oz. 1 Sugar lb. 2 All in powder; mix well. II. Thomsonian (from the Guide and the Materia Medica). Poplar bark oz. 10 Bayberry oz. 2 Balmony oz. 2 Golden seal oz. 1 Clove oz. 1 Capsicum oz. y 2 Sugar oz. 16 All in powder ; mix well. III. Thomsonian (from Comfort's Practice). White aspen poplar bark oz. 3 Black aspen poplar bark oz. 3 Ginger oz. 2 Golden seal oz. 2 Cinnamon oz. 1 Clove oz. 1 Prickly ash bark oz. y 2 Capsicum oz. l / 2 Sugar lb. 8 or 9 All in fine powder; mix well. Bitters, Spice, Ladies'. (Woman's Friend.) Poplar bark lb. 5 Gov lb. Capsicum oz. 4 Sugar lb. 8 All in fine powder ; mix well. Another method of preparation is to add the powdered myrrh and unicorn root to the spice bitters in equal amount with the clove.— Thomsonian (from Comfort's Practice). Bitters, Wine. I. Thomsonian (from the Guide and the Materia Medica). Balmony part 1 Poplar bark parts 5 Boil one ounce in enough water so that when strained there will be i]4 pints of liquid, to which add, while hot, 3 x / 2 ounces of sugar and 5/32 ounce of powdered ladies' slipper, strain, add i^4 pints best Malaga wine and 2 fluid- ounces each of tincture of meadow fern and prickly ash berries. II. Thomsonian (from the Guide and the Materia Medica). Poplar bark oz. 5 Balmony oz. 1 Water pints j l / 2 Sugar oz. 20 Ladies' slipper, powder oz. 1 4th-proof Jamaica rum or brandy pints 2 Malaga wine pints 10 Tincture of meadow fern. . .fl.oz. 8 Tincture of prickly ash bark. fl.oz. 8 Boil the poplar and balmony with the water, strain, add while hot, the sugar and ladies' slipper, strain again and add the other ingredients. The strength of the two tinctures is not stated. III. Thomsonian (from Comfort's Practice). Cinchona oz. I Gentian oz. 1 Columbo oz. 1 Virginia snakeroot oz. y 2 Add a portion of orange peel and 2 quarts of good Madeira or Sherry wine. IV. For the eclectic "wine bitters," see Wine of Golden Seal, Compound. Blood, Dried Defibrinated. (Sanguis Bovinus Inspissatus or Exsicca- tus.) This may be prepared by evaporating fresh defibrinated bullock's blood on a water bath, stirring constantly, until it assumes a granular condition ; then spread on glass plates or parchment paper and keep at a temperature of 30 to 35 degrees C. (in a drying oven) until perfectly dry, after which it is powdered and put into well-stoppered bottles. The defibrinated blood may be pre- pared by vigorously beating fresh blood in a broad dish with a stick or twig until there is no further separation of fibrin. -D. PHARMACEUTICAL PREPARATIONS. 23 Boroglycerin. (Glyceryl Borate. — Boroglyceride. — Glycerite of Boric Acid.) Boric acid, fine powder av.oz. 10 Glycerin av.oz. 14% Heat the glycerin in a tared porcelain capsule to a temperature not exceeding 150 degrees C, and add acid in por- tions, constantly stirring. When all is added and dissolved, continue the heat at the same temperature, frequently stir- ring, and breaking up the film which forms on the surface. When the mix- ture has become reduced to a weight of 16 av. ounces, pour it out on a flat sur- face previously coated with a very small quantity of petrolatum, let it cool, cut it into pieces and transfer them imme- diately to bottles or jars, which should be well-stoppered. The official glycerite of boroglycerin may be made from this by adding an equal weight of glycerin to the finished boroglycerin while it is still warm. When a solution of boroglycerin is required, it is preferable to prescribe or dispense the glycerite of boroglycerin of the N. F. Bougies. See Suppositories. Brandy, Proof. The standard of proof for alcoholic liquids was 50 per cent by volume of ab- solute alcohol and 50 per cent of water. Second proof was 52 l / 2 per cent of abso- lute alcohol; third proof was 55^ per cent, and fourth proof was 58 per cent. These were London proof. Brandy was formerly official in U. S. P. Caffeine, Citrated. Caffeine (alkaloid) av.oz. 1 Citric acid av.oz. 1 Distilled water, hot fl.oz. 2 Dissolve the acid in the water, add the caffeine and evaporate the resulting solution on a water bath to dryness, constantly stirring towards the end of the process.. Reduce the product to fine powder and transfer to well-closed bot- tles.— U. S. P. Considerable confusion exists in re- gard to caffeine. It was formerly the custom of manufacturers to put up caf- feine alkaloid under two labels, "caf- feine" and "caffeine citrate." Caffeine is now put up under its proper label; caffeine citrate, true salt, is also to be had ; and finally there is the above citrated caffeine. When physicians pre- scribed caffeine citrate, it was the alka- loid that was dispensed, and it is quite likely that when they now prescribe caffeine citrate, they intend the same article that was formerly dispensed, viz., the alkaloid. The U. S. P., however, intends that when, caffeine citrate is pre- scribed, the above citrated caffeine should be dispensed. Caffeine Sodio-Benzoate. Caffeine (alkaloid) av.oz. I Sodium benzoate av.oz. I Water sufficient. Dissolve the caffeine and the sodium benzoate in 2 fl, ozs. of water and evap- orate to dryness on a water bath. Rub the dry mass to powder, and keep in well-stoppered bottles. This is not a definite chemical com- pound, but a mixture. — U. S. P. Caffeine Sodio-Salicylate. Caffeine (alkaloid) av.oz. I Sodium salicylate av.oz. I Alcohol, sufficient. Triturate the caffeine with the sodium salicylate and a sufficient quantity of alcohol to a smooth paste, and dry this by exposure in a moderately warm place. Rub the dry mass to powder, and keep it in well-stoppered bottles. The product contains 50 per cent, of caffeine, and is soluble in 2 parts of water. — N. F. According to the Germ. Pharm., this preparation is to be made as follows : Caffeine, alkaloid av.oz. 5, Sodium salicylate av.oz. 6 Water fl.oz. 19 Dissolve the solids in the water and evaporate to dryness. 24 STANDARD FORMULARY OF Calcium Sulfid. (Hepar Sulfur.) The homeopathic article should be prepared according' to Hahnemann's di- rections, by mixing equal weights of clean and finely powdered oyster shells and washed sulfur, placing this in a hermetically-closed clay crucible, and keeping the mixture at a white heat for 10 minutes. The product is to be cooled and preserved in glass-stoppered bottles, protected from light. Camphor, Carbolized. (Phenol Cam- phor.) Carbolic acid, crystal, part I by weight. Camphor, triturated parts 2 Mix in a bottle and agitate frequently until liquefied. — D. Camphor, Chloral. (Camphorated Chloral. — Chloral and Camphor. — Chloral with Camphor.) Chloral hydrate. Camphor, equal parts by weight. Mix by agitation in a bottle or tritura- tion in a warm mortar until liquefied and combined. — N. F. and Brit. Form. Camphor Cream. This mixture has been known by this name : White castile soap gr. 120 Ammonia carbonate gr. 120 Camphor, powder gr. 120 Tincture of opium fl.dr. 2 Oil of origanum fl.dr. 1 Water to make fl.oz. 16 Dissolve the soap in 4 or 5 times its weight of boiling water, allow the solu- tion to cool, add the remaining ingredi- ents, and mix well. Sometimes this is made with double the amount of soap and is also made to contain 1 fluidounce of oil of turpentine to the pint. A formula for a toilet preparation by the name of "Cream of Camphor" may also be found in the book on toilet preparations. Camphor Julep. This preparation has been credited to Thomsonian practice : Camphor gr. 60 Myrrh gr. 210 Sugar gr. 120 Water .fl.oz. 4 Triturate the solids together until well mixed, then gradually incorporate the water. Camphorated Menthol. Camphor. Menthol, equal parts by weight. Reduce the two separately to powder, then mix them, and triturate until the mixture is completely liquefied. — N. F. Capsules, Gelatin, Sealing of. Soft or elastic gelatin capsules are now furnished empty so as to be filled with any desired medicament. To seal them after filling, use a mixture of 6 drams of gelatin, 6 fluidrams of water and 2 fluidrams of glycerin. Mix these in a wide-mouth bottle, stopper the lat- ter, and heat on a water-bath till the gelatin is all dissolved. The solution should be applied hot with the end of a rather broad round piece of wood. Great care must be exercised in filling the capsules not to get any of the liquid on the neck of the capsule. The ordinary variety of gelatin cap- sule may be filled, if desired, with liquid and sealed with the same solution, in this case painting or daubing the inside of the cap with the solution immediate- ly before putting it on the body of the capsule. The Germ. Pharm. specifically men- tions capsules, but two kinds are de- scribed, one being the ordinary gelatin capsule, the other the so-called cachet or konseal. The new N. F. also directs under the heading Powders that powders or tritu- rations may be dispensed enclosed in hard capsules of gelatin. Carbolated Chloral. (Chloral-Phenol.) This is prepared by the triturating to- gether equal parts by weight of chloral hydrate and crystal carbolic acid. PHARMACEUTICAL PREPARATIONS. 25 Cataplasms. See Poultices, also Cataplasm of Kao- lin. Cataplasm of Kaolin. (Kaolin Paste.) Kaolin, very fine powder, .av. oz. 9 r A Boric acid, very fine powder.av.oz. 74 v Thymol gr. 4 Methyl salicylate gr. 15 Oil of peppermint, gr. 4 (about 6 drops). Glycerin av.oz. 6 Heat the kaolin in a suitable vessel at 100 deg. C. with occasional stirring, for one hour; mix it intimately with the acid, and then incorporate thoroughly with the glycerin, which has previously been dehydrated by heating to 100° C. ; finally add the thymol which has pre- viously been dissolved in the methyl sali- cylate and oil, and make a homogeneous mass. — N. F. Catgut Ligatures. Wliat is known as catgut is prepared from the intestines of different animals, but usually of the sheep. To. prepare the gut, the intestines are cleaned, me- chanically freed from adherent fat, steeped for some time in water, after which the external membrane is scraped with a blunt tool like the back of a knife. The membrane is then cut into strips, bleached possibly, washed repeat- edly in alkaline liquids and in water, sometimes dyed, dried, twisted or rolled, then smoothed, the last two operations being done by machinery, and finally is rubbed with a cloth impregnated with some fatty oil. The catgut most commonly seen is that used as strings for musical instru- ments. Certain sizes of these strings are suitable for use as ligatures. These are what are known as the first and second banjo, and violin E, A, and D. These correspond to the sizes of liga- tures known as Nos. o, 1, 2, 3 and 4. Nos. 1, 2 and 3 are most generally em- ployed. Owing to the application of oil to the catgut before cutting to proper lengths and tying them into skeins, the ligature cannot be said to be in an aseptic con- dition if treated merely with an aqueous solution of carbolic acid (with or with- out chromic acid) or with cold alcohol with or without added antiseptic, al- though catgut so treated is used by surgeons. The gut should preferably be freed from fatty matter or at least it should be thoroughly penetrated by an actual solvent of the fatty matter, which solvent will, at the same time, render permanently sterile any septic matter or germs that may be contained in the gut. The fatty matter may be removed by maceration in chloroform, stronger ether or oil of juniper berries, or by boiling with absolute alcohol un- der pressure to no deg. C. or more. Treatment with these agents removes the fatty matter and at the same time renders the gut sterile. Among other methods for sterilizing catgut (besides those mentioned under succeeding articles) are: 1. Maceration in oil of juniper ber- ries and subsequent boiling with U. S. P. alcohol, then transferring to and keeping in biniodized chloroform (chlo- roform saturated with red mercuric iodid). 2. Treatment as in No. 1, but with omission of the oil. 3. Maceration for at least 48 hours in biniodized chloroform. The strings are to be left in this solution and taken out as required. The gut may be boiled conveniently with U. S. P. alcohol (or other desired liquid) in a wide-mouthed glass flask provided with a well-cooled upright con- denser which causes the condensed liq- uid to flow back into the flask. Catgut cannot be boiled under pressure with alcohol much weaker than absolute al- cohol without softening and weakening it, and it is best not to continue the boiling for more than about an hour. 26 STANDARD FORMULARY OF When boiling the gut in any of the above-mentioned liquids, the skeins may be suspended in the liquid as they are, or they may be wound on a reel or spool (preferably of glass), or they may be wound on a test-tube and the latter be loaded with shot so as to sink it in the liquid. A firm manufacturing antiseptic dress- ings thus describes its process for ster- ilizing catgut : i. Exterior cleansing of the ligatures by scrubbing. 2. Removal of moisture. 3. Winding in coils and sealing with- in a toughened filter-paper envelope, this envelope is closed with an antiseptic cement which is germproof, but allows the disinfecting solutions used after- wards to pass through. After the liga- tures are sealed in this envelope, they are not touched by any one until they reach the surgeon. 4. Successive percolation with solv- ents, naphtha, ether, benzol, alcohol, etc., for the removal of dirt, blood, foreign material, etc., within the tissue of the gut. 5. Sterilizing by boiling in a solution of cumol compound at a temperature of 160 to 170 deg. C. 6. Removal of cumol compound. 7. Sealing in a second or outer en- velope and final packing in sterilized glass jars. The biniodized chloroform or "chlo- roform with biniodid" is prepared by adding 35 grains of red mercuric iodid to 5 pounds of pure chloroform con- tained in a flask provided with an up- right condenser, and boiling until the salt is dissolved, which requires about half an hour. The solution should then be transferred to bottles, which must be well stoppered. The solution is of the strength of 1 in 1,000, and at the ordinary indoor temperature is perma- nent. When exposed to a temperature of 15 deg. C. or less, some of the salt will crystallize out, but not much, un- less the temperature is quite low. The mixture may assume a pink tinge due to the presence of loose chlorin com- pounds in the chloroform which liberate iodin from the iodid. Catgut, Alcohol. This is raw catgut treated with alco- hol before use, as described above un- der Catgut Ligatures. Catgut Ligatures, Carbolated. I. Lister's process (in D.) : Carbolic acid, crystal av.oz. \Y\ Distilled water fl.dr. 1 Olive oil fl.oz. 7 Mix in a wide-mouth glass bottle or other suitable vessel. Place in the mix- ture as much catgut as is to be impreg- nated, adding more liquid if necessary, to completely immerse the gut. Allow the gut to remain in the turbid fluid until the latter becomes clear, agi- tating from time to time. When the liquid becomes transparent, the gut will have become soft and have absorbed water and acid. It is now wound upon glass spools, the whole then being im- mersed in a mixture of crystal carbolic acid and olive oil in the proportion of 1 of the former to 4 of the latter. This is also the process of the mili- tary pharmacopeia of Austria. II. Block's process (in D.) : Roll the cleansed catgut upon glass spools, macerate in a 5 per cent, aqueous solution of carbolic acid for 48 hours, then unwind in a dish containing a freshly prepared 5 per cent aqueous car- bolic acid solution, and now rewind (tightly) the gut upon the spool. Pre- serve in a 5 per cent solution of car- bolic acid in alcohol. III. Block's carbolic-alcohol process (in D.) : Prepare like the preceding, using an alcoholic solution of carbolic acid in- stead of an aqueous one as above. Catgut Ligatures, Chromicized. Chromic acid gr. 2 Carbolic acid, crystal gr. 400 Distilled water fl.oz. 17^ PHARMACEUTICAL PREPARATIONS. 27 Dissolve and add an amount of catgut equal in weight to the carbolic acid used; allow to remain in the solution for 48 hours, then remove, dry, wind upon glass spools, and place in 20 per cent, carbolized oil. This is Lister's process for hardening gut so that it will not be readily ab- sorbed.— D. Catgut Ligatures, Formaldehyde. The raw catgut, wound on glass spools, is to be freed from fat by ex- traction with ether in the usual manner, and then placed in a sterile glass jar with a mixture of equal parts of 95 per cent, alcohol and 40 p. c. formaldehyde solution for 6 days, the jar being secure- ly closed. The liquid is then to be poured off and the gut then boiled in normal salt solution for 20 minutes. The boiling may be repeated the next day. The gut is then to be transferred to sterile bottles with a sterile forceps and kept in alcohol. Catgut Ligature, Mercuric Chlorid. (Corrosive Sublimate or Sub- limated Catgut.) I. Bergman's process (in D.) : Catgut rolled on glass spools is to be placed in 5 per cent, alcoholic solution of mercuric chlorid, renewing the solu- tion every 2 days, until it remains clear, then preserve the gut in this solution. II. Schede-Kuemmell process (in D.) : Catgut rolled upon glass spools is to be placed for 12 hours in a 1 per cent, aqueous solution of mercuric chlorid; then preserve in y 2 per cent, alcoholic solution of the same salt to which has previously been added 10 per cent, of glycerin. Catgut Ligatures, Oil Juniper. Macerate catgut for 24 hours in oil of juniper berries, then wind upon spools and preserve either in this oil or in the following solution : Mercuric chlorid gr. 4 Glycerin * fl.dr. 10 Alcohol fl.oz. 16 — Kocher's process (in L\). Caustic, Arsenical, Ratier's. Arsenous acid gr. 5 Kino gr. 40 Cinnabar gr. 80 All should be in very fine powder. Caustic, Black, Velpeau's. Triturate powdered licorice root in a mortar, adding sulfuric acid until a suit- able mass is formed. Caustic, Filhos\ Caustic potash parts 2 Lime . part 1 Fuse together and cast into pencils. Caustic, Vienna. See Potassa with Lime. Cearin. This is an ointment vehicle, proposed by Islieb, composed of 1 part of liquid paraffin and 4 of carnauba wax. It dif- fers from paraffin ointment of the Germ. Pharm. in containing carnauba wax in- stead of paraffin. Cerate, Benzoated. Yellow wax part 1 Benzoinated lard parts 2 — Eclectic. Cerate, Brown. (Brown Cerate or Ointment. — Mutter Salbe. — TJn- guentum Fuscum. — Emplastrum Fuscum Molle.) I. Austr. Pharm. : Lead plaster .av.oz. 5 Yellow wax .av.oz. 2 Lard av.oz. 3 Melt the lead plaster and stir con- stantly while liquid, until it assumes a dark brown tint ; add the wax and lard ; allow to cool somewhat, and pour into molds. II. D.: A more rational and easy method of preparation is the following : Black mother plaster av.oz. 5 Lard av.oz. 4 Yellow wax av.oz. 1 Melt the plaster and wax, add the lard, allow to cool somewhat, and pour into molds as before. Cerate, Calamine. (Turner's Cerate. — Cerate of Zinc Carbonate.) Zinc carbonate av.oz. 1 Simple cerate av.oz. 5 —Eclectic- 28 STANDARD FORMULARY OF Under the name Turner's Cerate or Calamine Ointment, the N. F. gives a preparation of the same strength as the above, but made with simple ointment. Cerate, Calendula. This may be prepared as follows : Lard, fresh av.oz. 8 Fluid extract of calendula. . .fl.oz. i Heat on a water bath until the alcohol has - evaporated, stirring frequently meanwhile. Another method consists in digesting the flowers with melted lard for about 10 minutes, stirring occasionally; then strain, and stir frequently until cooled. It is advisable to add about 2 av.ounces of yellow wax. Cerate, Camphor. Camphor liniment fl. or av.oz. 1^4 White petrolatum av.oz. 2^4 White wax av.oz. s l A Benzoinated lard av.oz. 6 Melt the wax. add the petrolatum, then the benzoinated lard, and continue the heat until the mixture is liquefied. While the mixture is cooling, add the camphor liniment and incorporate by stirring until it congeals.— N. F. Cerate, Cantharides. (Blistering Ce- rate or Plaster. — Cantharides Plaster. Cantharides, No. 60 powder. av.oz. 7 Glacial acetic acid fl.oz. Y 2 Oil of turpentine fl.oz. 3 Yellow wax av.oz. Z l / 2 Rosin av.oz. 3 l / 2 Benzoinated lard av.oz. 4 Moisten the cantharides with the oil of turpentine and acetic acid, and set the mixture aside, well covered, in a warm place, for 48 hours. Then add it to the rosin wax and lard, previously melted and strained through muslin, and keep the mixture in a liquid condition by means of a water bath, stirring occa- sionally, for one hour. Finally remove it from the bath, and stir until the mix- ture begins to congeal.— U. S. P. In the U. S. P., 1890, the cantharides was extracted with oil of turpentine. See also Cerate of Extract of Can- tharides. Cerate of Copper Subacetate. (Cera- tum Aeruginis. — Ceratum Viride. — Green Cerate.) Yellow wax av.oz. 6 Resin av.oz. 3 Gum turpentine av.oz. 2 Verdigris, powder av.oz. y 2 Mix the wax, resin, and turpentine together, add the verdigris, which has previously been triturated to a smooth paste with some of the melted mixture, mix well, and pour into molds. — H. Cerate, Croton Oil. (Ceratum Tigli- um.) Lard av.oz. 5 White wax av.oz. 1 Croton oil fl.oz. 2 Melt lard and wax together, when nearly cold add the oil, and stir until solid. — Eclectic. Cerate of Extract of Cantharides. Cantharides, No. 60 powder. av.oz. 3 Resin av.oz. 1 y 2 Yellow wax av.oz. 3^2 Lard av.oz. 3^2 Alcohol '. sufficient Moisten the cantharides with 2 fluid- ounces of alcohol and pack firmly in a cylindrical percolator ; then gradually pour on alcohol until 17 fluidounces of percolate are obtained, or until the can- tharides are exhausted. Distil off the alcohol by means of a water bath, transfer the residue to a tared capsule and evaporate it, on a water bath, until it weighs V/ 2 av.ounces. Add to this the resin, wax and lard previously melt- ed together and keep the whole at a temperature of 100 deg. C. for 15 min- utes. Lastly, strain the mixture through muslin and stir it constantly until cool. — N. F. Appendix and U. S. P. 1880. See also Cerate of Cantharides. Cerate of Lead Subacetate. (Gou- lard's Cerate.) Sol. of lead subacetate. . .av.oz. 3 Wool fat, anhydrous av.oz. 3 Paraffin av.oz. 3 White petrolatum av.oz. sH Camphor gr. 140 To the melted wool fat contained in a warm mortar, add the lead solution and incorporate by slow trituration. To PHARMACEUTICAL PREPARATIONS. 29 the mixture add the petrolatum and paraffin, previously melted and in which the camphor has been dissolved; mix thoroughly until homogeneous. — U. S. P. The corresponding preparation of the Germ. Pharm. is unguentum plumbi or lead ointment (different from diachylon ointment), which" is made by evapora- ting 2 parts by weight of solution of lead subacetate to I part and incorpora- ting with 19 parts of paraffin ointment. Cerate, Nutmeg. See Balsam, Nutmeg. Cerate, Paraffin. This has -been offered as a pleasant substitute for simple cerate: Paraffin dr. 4 White wax dr. 2 Sweet almond oil fl.oz. 1 Oil of rose drops 2 Cerate, Rosin. (Basilicon or Resin Ointment.) Rosin av.oz. S T A Yellow wax av.oz. 2 X A Lard av.oz. 7^/2 Melt the rosin, add the wax and lard, and continue the heat until liquefied, then strain the liquid through muslin, and allow it to congeal with occasional stirring. In cold weather, 8 av.ounces of lard and \Ya av.ounces of wax may be used. — U. S. P. For the corresponding preparation of the Brit, and Germ. Pharms., see Oint- ment, Resin. Cerate, Rosin, Compound. (Deshler's Salve.) Rosin av.oz. 4 Yellow wax av.oz. 4 Suet, prepared av.oz. 5^4 Gum turpentine av.oz. 2 Linseed oil, raw fl.oz. 2^/2 Melt the rosin, wax, turpentine and suet together, add the linseed oil, con- tinue the heat until the mixture is lique- fied, then strain through coarse muslin. — N. F. This is a new preparation reintro- duced from the U. S. P. 1870. Cerate, Savine. (Savine Ointment.) Fluid extract of savine fl.oz. 1 Resin cerate av.oz. 2>Va Melt the resin cerate by means of a water-bath, add the fluid extract, and continue the heat until the alcohol has evaporated; then remove the heat, and stir constantly until cool.— U. S. P. 1880. Cerate, Simple. (Cerate.) White wax av.oz. 2y 2 Benzoiriated lard av.oz. 6 Melt the wax by the heat of a water bath, add the lard, continuing the heat until the mixture is liquefied, and stir it constantly until it begins to congeal. For use in southern latitudes, and during the heated season in other lo- calities, y 2 av.ounce of lard may be re- placed by an equal quantity of white wax.— U. S. P. Cerate, Spermaceti. Spermaceti av.oz. 1 White wax av.oz. 3^ Olive oil av.oz. $y 2 Melt together the spermaceti and wax, then add the oil previously heated, and stir the mixture constantly until cool. The oil must be heated before adding to the waxes to avoid a granular prod- uct.— U. S. P. 1890. Charcoal, Animal, Purified. Animal charcoal, No. 60 powder av.oz. 8 Hydrochloric acid fl.oz. 21 Water, boiling sufficient Introduce the charcoal into a capa- cious flask, add 14 fluidounces of hydro- chloric acid and 32 fluidounces of boil- ing water, and connect the flask with an upright condenser. By means of a sand bath, keep the mixture boiling gently during 8 hours, adding water oc- casionally to maintain the original vol- ume. Then add 40 fluidounces of boil- ing water, transfer the mixture to a muslin strainer, and when the liquid has run off, return the charcoal to the flask, add to it 7 fluidounces of hydrochloric 30 STANDARD FORMULARY OF acid and 16 fluidounces of boiling water; boil for 2 hours ; again add 40 fluid- ounces of boiling water, transfer the whole to a plain filter, and when the liquid has run off, wash the residue with boiling water until the washings give only a faint cloudiness with silver nitrate test solution. Dry the powder in a drying oven and immediately trans- fer to well-stoppered bottles. — The hydrochloric acid must be of full U. S. P. strength, 31.9 per cent, of ab- solute acid, else proportionately more of it must be employed. It converts the calcium phosphate and carbonate present in animal charcoal into* chlorid and acid phosphate which are soluble in water and are removed by the washing. Chloral, Camphorated. See Camphor, Chloral. Chloral, Carbolated. See Carbolated Chloral. Chloral, Mentholated. Triturate together equal parts by weight of chloral and menthol, and then heat on a water bath until melted. This is used as an application for neuralgia. Chlorodyne. This was first introduced in England as a "combination of perchloric acid with a new alkaloid." The name "chlo- rodyne" was undoubtedly invented by Dr. J. Collis Browne, but Mr. Freeman, pharmacist, claimed to be the inventor of the preparation. Whether Browne's and Freeman's chlorodynes were exact- ly the same is not known, but there was no foundation for their claims that new vegetable principles were contained in their medicines. Dr. Ogden, of St. Mary's Hospital, London, published the following form- ula as a result of a pretended "analy- sis" : Morphine hydrochlorid gr. 8 Hydrocyanic acid, Scheele's drops 12 Oil of peppermint drops 2 Perchloric acid drops 20 Tincture of cannabis indica.fl.dr. 1 Tincture of capsicum m. 30 Chloric ether fl.dr. 1 Molasses fl.dr. 1 Chloroform fl.dr. 6 The formula, actually used by Dr. Ogden in the hospital, appears to have been slightly different from this. Later, after the nostrum was intro- duced into America, Charles Bullock published the following formula as the result of an analysis : Morphine hydrochlorid gr. 8 Water m. 30 Perchloric acid (25 deg. B.) drops 20 Chloroform fl.dr. 1 ^ Tincture of cannabis indica.fl.dr. 1 Hydrocyanic acid, U. S. P.. drops 12 Molasses fl.dr. 4 Oil of peppermint drops 2 Oleoresin of capsicum drop 1 To the morphine salt and water con- tained in a flask, add the perchloric acid and heat until a clear solution is effect- ed. Then add the molasses, previously warmed so as to render it fluid. Heat the mixture and agitate well. When cold add the other ingredients and mix well. A number of other substitutes have been and are still in use, the formulas (there are about 30 published formulas and an innumerable number of private formulas) for which differ from another more or less, sometimes quite materially, both in kind and quantity of ingredients. The National Formulary recognizes one of these preparations under the name Compound Mixture of Chloroform and Cannabis Indica or "chloroform ano- dyne." The Brit. Pharm. preparation is called compound tincture of chloroform and morphine. Browne's preparation is thick, turbid, and brownish, but many of the other preparations now on the market arc limpid, transparent, and bright green in color. PHARMACEUTICAL PREPARATIONS. 31 The formulas given below are the ones which have proved the most popu- lar : Chloroform Anodyne — I. Chloroform fl.oz. 2 Stronger ether fl.dr. 4 Tincture of cannabis indica. fl.oz. 3 Tincture of capsicum fl.dr. 4 Morphine sulfate gr. 18 Oil of peppermint m. 15 Glycerin fl.oz. 2 Water fl.oz. 1 Alcohol, to make fl.oz. 16 Dissolve the oil in 8 fluidounces of alcohol, add the chloroform, ether and tinctures, mix well, add the morphine sulfate previously dissolved in the wa- ter and glycerin ; finally add the remain- der of alcohol. — N. F. II. Brit. Pharm. 1898 (which calls it compound tincture of chloroform and morphine) : Morphine hydrochlorid gr. 36 Diluted hydrocyanic acid, .fl.dr. 3*4 Tincture of capsicum m. 100 Tincture of cannabis indica fl.dr. ey 2 Oil of peppermint m. 6 Glycerin fl.oz. 2 Alcohol, to make fl.oz. 8 This preparation contains 4 times as much morphine as the corresponding preparation of the Brit. Pharm. of 1885. Otherwise it differs materially from the latter. See No. III. III. Brit. Pharm. 1885 (which called it tincture of chloroform and mor- phine) : Chloroform fl.oz. 1 Ether fl.dr. 2 Alcohol fl.oz. 1 Morphine hydrochlorid gr. 8 Diluted hydrocyanic acid. .. .fl.dr. 4 Oil of peppermint m. 4 Fluid extract of licorice fl.oz. 1 Molasses fl.oz. 1 Simple syrup, to make. fl.oz. 8 Dissolve the morphine and oil in the alcohol, and add the chloroform and ether. Mix the extract and molasses with 3 fluidounces of syrup, add to the solution, mix thoroughly, add the acid and the remainder of the syrup. IV. Chloroform fl.dr. 2 Morphine gr. 10 Ether . # fl.dr. 1 Oil of peppermint drops 8 Diluted hydrocyanic acid. . .fl.dr. 2 Tincture of capsicum fl.dr. 2 Molasses fl.oz. 2^2 Extract of licorice gr. 30 This is said to resemble Browne's very closely. V. Chandler's formula: Morphine hydrochlorid gr. 16 Oil of peppermint drops 20 Tincture of capsicum drops 30 Fluid extract of cannabis indica fl.dr. 1 Alcohol fl.oz. 2 Glycerin fl.oz. 2 VI. Smith's formula (modified) : Chloroform fl.dr. 4 Morphine hydrochlorid gr. 20 Oil of peppermint drops 8 Tincture of capsicum fl.dr. 1 Diluted hydrocyanic acid. . .fl.dr. 2 Mucilage of acacia fl.oz. 1 Fluid extract of cannabis indica fl.dr. 2 Simple syrup, to make fl.oz. 4 Caramel, sufficient to color properly. VII. Squires' formula: Chloroform fl.oz. I Stronger ether . . . ^ fl.dr. 2 Alcohol fl.oz. I Molasses fl.oz. 1 Extract of licorice, powder.. gr. 300 Morphine hydrochlorid gr. 2 Oil of peppermint drops 4 Simple syrup fl.oz. 4^ Diluted hydrocyanic acid, .fl.dr. 4 Dissolve the morphine and oil of pep- permint in the alcohol, mix the chloro- form and ether with this .solution, mix the licorice with the syrup, add the mo- lasses, shake these two mixtures well together, and, lastly, add the hydro- cyanic acid and again shake well. VIII. Gilman's formula : Chloroform .fl.dr. 2 Spirit of peppermint fl.dr. 2 Diluted hydrocyanic acid. .. .fl.dr. 2 Tincture of capsicum fl.dr. 2 Morphine hydrochlorid gr. 8 Glycerin fl.oz. 2 Alcohol fl.oz. 2 Molasses fl.oz. 3 32 STANDARD FORMULARY OF IX. Fenner's formula No. I : Chloroform fl.dr. 4 Ether fl.dr. 2 Diluted hydrocyanic acid. . .fl.dr. 4 Tincture of capsicum fl.dr. 4 Mucilage of acacia fl.oz. 1 Morphine sulfate gr. 20 Oil of peppermint m. 8 Molasses fl.oz. 4 Mix the chloroform with the mucilage and shake, add the oil and molasses; dissolve the morphine in the tincture, and add this solution with the other liquids to the mixture of syrup, etc., and shake them thoroughly. This is stated to be very similar to Browne's. X. Fenner's formula No. 2: Morphine sulfate gr. 15 Chloroform fl.oz. 1 Fluid extract of cannabis indica fl.oz. 1 Glycerin fl.oz. 1 Alcohol fl.oz. 1 Diluted hydrocyanic acid, .drops 15 Spirit of peppermint drops 15 Mix the liquids and dissolve the mor- phine in the mixture. XI. A prominent manufacturing house makes a preparation called "chlo- ranodyne" which is stated to contain in each fluidounce — Morphine hydrochlorid gr. 2^8 Fluid Indian cannabis m. 46 Chloroform m. 46 Oil of peppermint m. 1J/2 Tincture of capsicum m. i l / 2 Diluted hydrocyanic acid m. 9 This is similar to No. II. Chloroform of Aconite. (Aconite Chloroform.) Aconite root av.oz. 11 Ammonia water fl.oz. 2 Distilled water fl.oz. 10 Chloroform sufficient Bruise the aconite, moisten thorough- ly with the distilled water and ammonia previously mixed, macerate for 4 hours, dry carefully, reduce to Xo. 40 powder, pack tightly in a percolator (such as would be used for highly volatile liq- uids), macerate for 24 hours with 11 fluid ounces of chloroform, and then percolate slowly, adding more chloro- form until 16 fluidounces of product are obtained. — Brit. Form. "Chloroforms'' of other alkaloidal drugs, such as belladonna, hyoscyamus, etc., may be produced in the same man- ner. Chloroform of Belladonna. (Bella- donna Chloroform. Prepare like the preceding, using belladonna root in Xo. 60 powder as the drug. — Brit. Form. Chloroform, Camphorated. Chloroform fl.oz. 4 Camphor av.oz. 8 Mix and dissolve. — Brit. Form. Cigarettes, Cubeb. While it probably will not pay the pharmacist to prepare his own cubeb cigarettes, the following hints and form- ula may not be amiss : The first step in the process of manu- facture is the molding of the casement of the cigarettes, which consists in forming into a sound hollow tube cigar- ette paper about 3 inches long and about 34 inch in diameter. The ordinary round lead pencil will answer for a mold around which the paper can be rolled — when the paper tube is formed, turn in one of the ends so as to form the bot- tom. Now place a number of these tubes into a rack, and by the use of a s sieve of the proper fineness the mixture of drugs is sifted over the paper tubes until they are filled up within an inch of the top, after pressing the mixture so that it is evenly distributed a small piece of cotton is placed over it and a mouthpiece is inserted, which is made out of a piece of cardboard one inch long and a trifle smaller in diameter so that it can be inserted into the paper tube and the cigarette is finished. Ten or thirty of these are then wrapped in paraffin paper and placed in a paper carton with printed directions for use. The mixture used for filling varies with different manufacturers ; the fol- lowing are said to be used: Cubeb berries part 1 Cubeb berries, exhausted. .. .parts 3 Mullein leaves part 1 PHARMACEUTICAL PREPARATIONS. 33 Or— Cubeb berries .parts 9 Anise seed .part 1 Or— Cubeb berries part 1 Cubeb berries, exhausted. .. .parts 4 Cpltsfoot leaves part 1 Or- Cubeb berries parts 7 Mullein leaves parts 2 Lobelia herb part 1 Or— Cubeb berries parts 15 Cassia buds part 1 Cloves part 1 Chestnut leaves parts 3 Or— Cubeb berries parts 2 Cubeb berries, exhausted. . .parts 10 Mullein leaves parts 4 Cascarilla bark part 1 The drugs should be ground to No. 20 powder. Some manufacturers add to the mixture of drugs glycerin and potassium nitrate, to increase the burn- ing quality of the cigarette. The usual quantity is 1 av.ounce of the potassium salt to a pint of water, or 4 fluidounces of glycerin and 12 fluidounces of water, either of these to be added to 10 av. pounds of the mixture of drugs, the whole then to be thoroughly dried. Each of the cigarettes contains about 15 grains of the mixture. The paper casements or tubes are an article of the market, and can be pur- chased at 50 cents per thousand from manufacturers. At this figure it hardly would be profitable for the beginner to make them himself. Several of the formulas contain ex- hausted cubeb berries. If these cannot be purchased, the .crushed berries can easily be exhausted of a large percent- age of the oil of cubeb by solvents like ether, carbon bisulphide or benzin. Ben- zin would seem to be the best, as it is readily obtained of very light gravity in the market and at a very low price. The oil of cubeb so extracted can be puri- fied and thus becomes an extra source of profit in this line of manufacture. It is stated that where the excess of oil is not removed, the paper casement be- comes stained, and it is also objection- able in the smoking of the cigarette, as some of the oil is carried into the mouth. As is well known, these cigarettes are used in catarrh, hay fever, asthma, etc. Ether, stronger Alcohol Collodion. Pyroxylin (soluble gun cotton) gr. 290 fl.oz. 12 fl.oz. 4 To the pyroxylin, contained in a suit- able bottle, add the ether and let stand for 15 minutes; then add the alcohol and shake the bottle until the pyroxylin is dissolved. Cork the bottle well and set it aside until the liquid has become clear. Finally decant the clear portion from any sediment which may have de- posited, and transfer it to bottles which should be well corked and sealed. Keep in a cool place remote from lights and fire.— U. S. P. Acetone is said to be an excellent solvent for pyroxylin and inight be sub- stituted for the alcohol and ether. The Brit. Pharm. directs only 150 gr. of pyroxylin for the above amount of liquid. The Germ. Pharm. uses 240 gr. of pyroxylin, agitates this with ify fluidounces of alcohol until well mixed, then with 1454 fluidounces of stronger ether. Collodion, Aconite. Such a preparation may be made as follows : Aconite root, fine powder. av.oz. Sy 2 Stronger ether fl.oz. 12 Alcohol sufficient. Balsam of fir gr. 240 Pyroxylin gr. 60 Pack the powder very tightly in a percolator intended for volatile liquids. mix the ether with 4 fluidounces of al- cohol, saturate the drug with this liquid, macerate for about 6 hours, then perco- late slowly, adding enough alcohol through the percolator so as to make 16 fluidounces of percolate. In this dis- solve the balsam and pyroxylin. 34 STANDARD FORMULARY OF Collodion, Belladonna. (Fluid Bella- donna Plaster.) Alcoholic extract of bella- donna leaf, a quantity containing 2>7 grains of alkaloids. Camphor gr. 108 Gun cotton gr. 185 Alcohol, stronger ether, each, to make fl.oz. 16 Dissolve the extract in yY 2 fluidounces of alcohol, add the same volume of stronger ether, set aside for 24 hours, decant, dissolve the gun cotton and camphor in the liquid, and equal parts of stronger ether and alcohol enough to make 16 fluidounces. — Brit. Form. Collodion, Benzoinated. (Kelly's Collodion Paint.) Glycerin fl.dr. 2 Compound tincture of ben- zoin fl.oz. 3 Collodion fl.oz. 6 This is used in New York City hos- pitals. Collodion, Cantharidal. (Blistering or Vesicating Collodion. — Collo- dion with Cantharides.) I. Cantharides, in fine powd..av.oz. 6 Glacial acetic acid min. 8 Flexible collodion av.oz. 9 Acetone to make av.oz. 10 Mix the cantharides with \ l / 2 drams of the acetone, to which the acetic acid has been added, and set the mixture aside in a closely covered container for 24 hours. Then pack it in a percolator, and per- colate with acetone until the drug is practically exhausted. Reduce the per- colate by distillation on a water bath in a tared flask to 24 grains. Dissolve this in the flexible collodion, allow the solu- tion to stand for several hours and de- cant the clear liquid. Keep Cantharidal Collodion in a cool place, remote from fire.— U. S. P. Cantharidin collodion may be used in place of cantharidal collodion as a vesi- cant if desired. II. Pyroxylin gr. 45 Blistering liquid fl.oz. 4 Mix in a well-stoppered bottle and dissolve by agitation. — Brit. Pharm. III. Exhaust coarsely-powdered cantha- rides with stronger ether, evaporate the liquid on a water bath to syrupy con- sistency, and add enough collodion to make up a weight equal to the original weight of the cantharides. — Germ. Pharm. Collodion, Cantharidin. Cantharidin gr. 3 Gum turpentine av.oz. 1 Chloroform fl.dr. 3 Collodion, to make fl.oz. 8 Triturate the cantharidin with the tur- pentine to as fine a powder as possible, then add the chloroform and heat the mixture very cautiously until solution occurs; then add to the collodion. If a green color be desired, add a small amount of Squibb's or English extract of cannabis indica. — D. modified. This contains 1/10 per cent, of can- tharidin. This may be used in place of cantha- ridal collodion, being more easily made and equally efficacious. Collodion, Carbolated Salicylic. Carbolic acid, crystal av.oz. I Salicylic acid av.oz. 1 Collodion fl.oz. 5 Mix and dissolve by agitation. The product contains one-third by weight of the combined acids. — Unna's (in D.). Collodion, Chrysarobin. Chrysarobin gr. 320 Collodion fl.oz. 8 The chrysarobin should be in very fine powder and be dissolved in the col- lodion by agitation. — D. The product contains about 10 per cent by weight of chrysarobin. It may be used instead of chrysarobin ointment. Collodion, Croton Oil. (Tiglium Col- lodion.) Croton oil av.oz. l /i Flexible collodion av.oz. 4^2 PHARMACEUTICAL PREPARATIONS. 35 Or mix in the proportion of 60 min- ims of oil with 7 fluidrams of flexible collodion. — N. F. Collodion, Flexible. (Elastic Collo- dion.) Collodion av.oz. 9]/ 2 Camphor grs. 85 Castor oil grs. 130 Weigh the ingredients successively into a tared bottle and mix them thor- oughly. Preserve in cork-stoppered bottles in a cool place remote from lights or fire. -U. S. P. The Brit. Pharm. directs 4 fluidounces of its collodion, 80 gr. of Canada tur- pentine and 40 gr. of castor oil. The Germ. Pharm. directs 4 av. ounces of its collodion, 18 gr. of castor oil and 90 gr. of common, thick turpentine. Collodion, Iodized. Todin, reduced to powder... gr. 160 Flexible collodion fl.oz. 8 Introduce the iodin into a bottle, add the flexible collodion and agitate until the iodin is dissolved. — N. F. This contains about 5 per cent, by weight of iodin. Collodion, Iodoform. Iodoform gr. 160 Flexible collodion fl.oz. 8 Mix and dissolve the iodoform in the flexible collodion by agitation. — N. F. This contains about 5 per cent, by weight of iodoform. Collodion, Iodol. Such a preparation may be made as follows : Iodol av.oz. }i Alcohol fl.dr. 11 Ether fl.oz. 6 Pyroxylin gr. 130 Castor oil, fl.dr. 3^ (or gr. 185 if weighed). Dissolve the iodol in the mixture of alcohol and ether, add the pyroxylin in small portions, agitate until dissolved, and finally add the oil. The product contains about to per cent, by weight of iodol. Collodion, Salicylated, Compound. (Corn Collodion.) Salicylic acid av.oz. 1 Extract of cannabis indica (Squibb's or English) gr. 80 Alcohol fl.oz. 1 Flexible collodion, to make. av.oz. 9 Dissolve the extract in the alcohol and the acid in about 5 ounces of flexi- ble collodion previously weighed into a tared bottle. Then add the former solu- tion to the latter and finally add enough of the collodion to make 9 av. ounces. — N. F. Collodion, Styptic. (Tannin Collo- dion.) I. Tannic acid av.oz. 2 Flexible collodion ..av.oz. 8 Add the tannic acid to the flexible col- lodion in a bottle and agitate the mix- ture until the tannic acid is dissolved. -N. F. This differs from the formula in U. S. P. VIII in using flexible collodion instead of collodion and omitting the ether. Keep the product in cork-stoppered bottles in a cool place remote from lights or fire. II. Benzoin gr. 44 Pyroxylin -. . gr. 44 Tannic acid av.oz. 1 Absolute alcohol fl.oz. 1 Stronger ether fl.oz. 4 Dissolve the benzoin in the alcohol, filter, in the filtrate dissolve the acid, add the other ingredients, set aside for 3 days and decant the clear liquid. , — Brit. Form. Collodion, Tannated. (Paves's Styp- tic Collodion.) Tannin gr. 150 Benzoic acid gr. 90 Carbolic acid, crystal gr. 300 Collodion fl.oz. 8 Mix and dissolve by agitation. Coloring Agents. A number of preparations are used for the purpose of imparting color to other preparations. The preparations. 36 STANDARD FORMULARY OF used for this purpose, mentioned in this part are cochineal color, solution of lit- mus, solution of carmine, tincture of cochineal, tincture of cudbear, compound tincture of cudbear, tincture of turmeric and tincture of saffron. Color, Cochineal. Cochineal, No. 50 powder. av.oz. 1 Potassium bitartrate av.oz. 1 Potassium carbonate av.oz. ^2 Glycerin fl.oz. 8 Alcohol fl.dr. 4 Water, to make fl.oz. 16 Triturate the cochineal intimately with the potassium carbonate and 8 fluidounces of water. Then add the alum and potassium bitartrate succes- sively, heat the mixture to boiling in a capacious vessel, then set it aside to cool, add to it the glycerin and alcohol, filter, and pass enough water through the filter to make 16 fluidounces. — N. F. Concentrations. This class of preparations was origin- ally introduced by physicians of the Eclectic school of medicine and subse- quently was employed by physicians of other schools. They are now employed in Europe; and one, at least, has found recognition in the U. S. P., viz., po- dophylin. The general plan for their manufac- ture originally consisted in extracting the drug with strong alcohol, evaporat- ing this tincture to small bulk, adding to cold water, stirring constantly mean- while, allowing the precipitate formed to subside, collecting the latter, and dry- ing and powdering it. If the drug contain an ojeoresin, the precipitate cannot be dried sufficiently to powder, but remains a soft, sticky mass. In this case, the precipitate should be dried sufficiently to remove the water, then add enough of the ori- ginal drug, in powdered form, to reduce to a rather tough mass, break the latter into small piece-, dry in warm air, and pulverize as before. In many instances, there would be, by the use of water alone as a precipitat- ing agent, an inappreciable amount of precipitate. In such cases, alum is added to the water and some ammonium car- bonate to the alcoholic liquid. The pre- cipitate contains aluminium hydrate, and the product will very often be green from precipitated chlorophyll. Other substances are added to the water to facilitate precipitation, such as acids and alkalies, depending, of course, upon the character of the drug. While the above methods of preparing concentrations were advised by Eclectic practitioners, other methods are or have been in vogue among manufacturers. In many instances, the concentration is simply a powdered extract, the so-called "euonymin," for example, the drug often being exhausted with dilute alcohol or water. Instead of using the powdered drug as a drying agent, as is stated above, most manufacturers use milk sugar, magnesia or other absorbent powder. Probably most concentrations of the present day are simply powdered extracts. See "Hydrastin" and "Iridin" for one method for making these concentrations. Most of the concentrations are sup- posed to be resinous in character, and are termed "resinoids," while others are alkaloidal in character. The latter are believed to be prepared by exhausting the drug with a very dilute acid (from Yi to 3 per cent.), usually hydrochloric or sulfuric, evaporating the liquid ob- tained to moderate bulk, adding am- monia to neutralize the acid, collecting the precipitate, and washing and drying it. Hydrastis and sanguinaria are drugs treated in this manner. As may be surmised from what has been stated, concentrations from differ- ent manufacturers differ from each other greatly in quality and strength and color, as well as in other properties. The nomenclature of the concentra- tions is very confusing. The resinoids have names ending in "in" — cornin, PHARMACEUTICAL PREPARATIONS. 37 helenin, etc. — while those of alkaloidal character are known by names ending either in "in" or "ia," and are coupled with names indicating the acid employed in extraction, e. g., hydrastia sulfate, sanguinarin nitrate, etc. Manufacturers of pharmaceuticals have not only modi- fied the processes of preparation, but have introduced innovations in the titles. When it is borne in mind that glucosides have names terminating in "in," and that aklaloidal names end in "ine" ("ia" is also used), and that al- most all drugs contain glucosides or alkaloids or even both, one can readily see that almost inextricable confusion must result, often to the serious detri- ment of sick persons. This is the case particularly with the derivatives of hydrastis and sanguinaria. The following table is presented be- cause of its convenience for reference. It will not apply to the products of all manufacturers, nor does it mention all concentrations, but it may prove useful nevertheless. Class I. Concentrations consisting largely of resin and nearly or entirely soluble in alcohol: Aletridin,* Asclepidin,* Cimicifugin (Macrotin), Eryngin,* Helonin,* Iridin,* Liatrin* Podophyllin (U. S. P.), Pte- lein.* Class II. Concentrations which gen- erally contain inorganic constituents from the process of manufacture, and are frequently of a green character : Barosmin, Euonymin (green variety), Lobelin, Lycopin, Podophyllin (yellow variety), Scutellarin, Senecin. Class III. Concentrations which con- tain a number (probably most) of the soluble drug constituents : Aletrin,* Alnuin, Ampelopsin, Apocy- nin, Asclepidin,* Baptisin, Betulin, Cau- lophyllin, Cerasin, Chelonin, Chimaphi- lin, Chionanthin, Collinsonin, Colocyn- thin, Cornin, Corydalin, Cypripedin, Dioscorin, Euonymin (brown variety), Euptaorin. Euphorbin, Eupurpurin, Fra- serin, Gelsemin, Geranin, Gossypin, Hamamelin, Humulin, Inulin, Irisin,* Jalapin, Juglandin, Leontodin, Leptand- rin, Liatrin,* Liriodendrin, Menisper- min, Myricin, Phytolaccin, Prunin, Rhusin, Rumicin, Smilacin, Stillingin, Taraxin, Trillin, Viburnin, Xanthoxylin. Class IV. Concentrations which con- sist of alkaloids or alkaloidal salts in more or less impure form : Hydrastin, Hydrastia Sulfate, Muri- ate, etc.; Sanguinarin, Sanguinarina Nitrate, Sulfate, etc. Those concentrations whose names have the stars appear in the market in both pulverulent and oleoresinous forms. Cones, Homeopathic. See Medications, Homeopathic. Confection of Calamus. (Sugared Calamus. — Candied Sweet Flag.) This may be prepared as follows : Calamus root, peeled, sliced and cut into pieces about Yz inch long av.oz. 8 Water fl.oz. 32 Sugar av.oz. 96 Macerate the root in the water for 12 hours, add the sugar, and heat, stirring constantly until perfectly dry. At first the evaporation may be conducted over a direct flame or fire, but toward the latter end of the operation, water-bath temperature only should be employed. Care must be taken not to burn or scorch the root. Confection of Hollyhock. (Conserve of Hollyhock. — Antidyspeptic Conserve.) I. Thomsonian (from the Materia Medica) : Fresh hollyhock blossoms lb. 1 Or dry ones moistened to the same consistence as the green. Sugar lb. 4 Poplar bark lb. 2 Ginger lb. 2 Golden seal lb. Y% Balmony lb. ^2 Clove lb. V2 Slippery elm bark lb. V? Capsicum lb. x : Pennyroyal oz. T 4 38 STANDARD FORMULARY OF Beat the blossoms with the sugar to a uniform paste, then incorporate the other substances, all in powder, and roll into small cones. These may be dried or kept moist as may be desired. II. Thomsonian (from Comfort's Prac- tice) : Poplar bark oz. Bayberry bark oz. Golden seal oz. Clove oz. Cinnamon oz. Cypripedium oz. Capsicum oz. y? Oil of pennyroyal oz. y 2 Hollyhock flowers oz. 16 Mix the first seven ingredients, add the oil and flowers, pound together, and form into balls the size of small marbles. Confection of Opium. (Electuary of Theriac. — Theriac.) I. Brit. Pharm. (1885): Compound powder of opium av.oz. 4 Simple syrup fl.oz. 9 II. U. S. P. 1870: Opium, powder gr. 120 Aromatic powder av.oz. 3 Clarified honey av.oz. 7 III. H.: Cassia bark av.oz. \Y\ Angelica root gr. 350 Virginia snake root gr. 280 Valerian root gr. 140 Squill gr. 140 Zedoary gr. 140 Opium gr. 70 Cardamom gr. 70 Clove gr. 70 Myrrh gr. 70 Iron sulfate, crystal gr. 70 Glycerin, Simple syrup. Honey, equal parts to each by weight, to make av.oz. 16 Mix the ingredients above in powder form, or preferably mix them whole, and then reduce to powder; then add the glycerin, syrup and honey. The cardamom should be used with- out the capsule or enveloping membrane. These preparations differ in many re- spects, but the most noteworthy differ- ence is in the proportion of opium, the first two containing about 2 l / 2 per cent. of this drug, the last about 1 per cent. ; the kind of confection to be dispensed therefore will depend on the nationality of the consumer or the kind he has been in the habit of using. Confection of Pepper. Black pepper, powder av.oz. 1 Caraway, powder av.oz. 1V2 Clarified honey ,. . .av.oz. 7/2 —Brit. Pharm. Confection of Rose. (Confection of Roses.) I. Red rose petals, fine powder.gr. 290 Sugar, fine powder av.oz. 5 Honey, clarified av.oz. 1 Stronger rose water fl.oz. 1J/4 Rub the red rose with the water pre- viously heated to 65 degrees C, then gradually add the sugar and honey, and beat the whole together until a uniform mass results. — N. F. II. F*esh red rose petals av.oz. 4 Sugar , av.oz. 12 Beat together in a stone mortar.— Brit. Pharm. Confection of Senna. (Lenitive Elec- tuary.) I. Senna, fine powder av.oz. 2 Cassia fistula, bruised av.oz. 3% Tamarind av.oz. 2 Prunes, sliced av.oz. \Y% Figs, bruised av.oz. 2^2 Sugar, fine powder av.oz. \\V\ Oil of coriander m. 50 Water sufficient. Place the cassia fistula, tamarind, prune and fig in a covered vessel with 10 fluidounces of water and digest for 3 hours by means of water bath. Separate the coarser portions with the hands, and rub the pulpy mass first through a coarse sieve and then through a fine one or through a muslin cloth. Mix the residue with 3 fluidounces of water and having digested the mixture for a short time, treat it as before and add the product to the pulpy mass first obtained. Then by means of a water bath, dis- solve the sugar in the pulpy liquid, and evaporate the whole in a tared vessel until it weighs 18 av. ounces. Lastly PHARMACEUTICAL PREPARATIONS. 39 incorporate the senna and oil with the pulpy mixture while the latter is yet warm. — N. F. t II. Senna, fine powder av.oz. I Simple syrup av.oz. 4 Tamarind pulp, purified. .. .av.oz. 5 Mix the senna with the syrup, incor- porate the pulp, and warm the whole on a water bath for an hour. — Germ. Pharm. Confection of Senna, Compound. Confection of senna av.oz. 1 Potassium bitartrate av.oz. ^2 Jalap, powder gr. 180 Potassium nitrate gr. 120 Sulfur gr. 120 Extract of butternut, enough to make a mass of pilular consistence. This has been used in constipation and in piles in doses of 10 to 15 grains given about twice daily. — Eclectic. Confection of Sulfur. I. Sulfur av.oz. 4 Cream of tartar av.oz. 1 Tragacanth, powder gr. 18 Tincture of orange, Brit. Pharm fl.dr. 4 Mix well. — Brit. Pharm. II. Sulfur av.oz. 4 Cream of tartar av.oz. 1 Syrup of orange fl.oz. 4 Tragacanth, powder gr. 18 Mix intimately. — Eclectic. Confection of Turpentine. Oil of turpentine fl.oz. 1 Licorice root, powder av.oz. 1 Honey fl.oz. 2 Mix the oil and powder, then incor- porate the honey. — Eclectic. Conserves. In conformity with the custom of the N. F., preparations formerly under this title are here classed with the con- fections. Copper, Aluminated. (Lapis Divinus. — Augen Stein.) Copper sulfate, pure av.oz. 2 Potassium nitrate ...av.oz. 2 Potassa alum av.oz. 2 Camphor gr. 55 Triturate the three salts separately to fine powder, then mix, melt carefully in a porcelain evaporating dish over a hot fire, then quickly add the camphor in a powdered state and previously mixed with an equal weight of powdered alum, and pour the whole out on a porcelain slab. When cold, it may be broken into pieces or rubbed to powder, and then preserved in well-stoppered bottles. — Germ. Pharm. Copper, Ammoniated. (Ammonio— Sulfate of Copper.) Ammonium carbonate av.oz. 3 Copper sulfate av.oz. 2 Triturate together in a glass mortar until effervescence ceases, then lay be- tween folds of bibulous paper and dry with a gentle heat.— U. S. P. 1870. Keep in well-stoppered bottles. Cordials. The above title is applied to many preparations which vary greatly in char- acter, and could not properly be placed under one heading. Some occur under other more appropriate titles in this book. Consult index. Cordial, Blackberry. (so-called Blackberry Brandy.) Cinnamon, No. 40 powder... gr. 310 Clove, No. 40 powder gr. 78 Nutmeg, No. 40 powder gr. 78 Purified talc gr. 124 Syr. blackberry fruit Diluted alcohol sufficient Percolate the powdered spices with diluted alcohol to obtain 8 fluidounces of tincture. To this add' sufficient syrup of blackberry fruit to make the product measure 32 fluid-ounces, mix, add the purified talc and filter. — N. F. This differs from the preparation of the former N. F. principally in the sub- stitution of blackberry syrup for black- berry fruit. Cotton, Absorbent. (Purified Cotton, U. S. P. — Gossypium Purifica- tum.) Ordinary cotton contains, in addition to the dirt and other matter that ac- companies it, some fatty and coloring 40 ST A N D ARD FO R M U L A R Y OF matter. The fatty matter does not per- mit the cotton to absorb water or aque- ous fluids to any appreciable extent, and the unpurified is therefore of no value for surgical and pharmaceutical pur- poses. There are several methods by which ordinary cotton may be rendered absor- bent. An easy process is to wash it re- peatedly with ether, which, of course, extracts or dissolves out the fatty mat- ter. The first portions of ether may be economically replaced by gasolin or petroleum ether, finishing the washing with ether so as to avoid the odor of gasolin in the product. By means of this process cotton can be rendered ab- sorbent and be dried in a very few minutes. The process adopted by manufactur- ers on the large scale is usually about as follows : Boil any desired quantity of the best carded cotton with a 5 per cent, solu- tion of caustic potassa or s®da for one- half hour, or until the cotton is entirely saturated with the solution, and the al- kali has saponified all the fatty matter ; wash thoroughly in clear water to re- move all the soap and nearly all the alkali; press out the excess of water; place in a 5 per cent, solution of chlorin- ated lime, allowing to remain for 15 or 20 minutes ; again wash, first in some clear water, then dip in water acidulated with hydrochloric acid, and wash again thoroughly in clear water; press out the excess of water and again boil for 15 or 20 minutes in 5 per cent, alkali solu- tion; now wash well in clear water, dip in water acidulated with hydrochloric acid, and again wash thoroughly in clear water; now press out the water and dry. Owing to the cellular character of cot- ton, it is very likely to absorb a liquid and not readily give it up again; hence when cotton is to be well washed, it should be kneaded with the hands or otherwise. In removing excess of water or other liquid, an ordinary clothes- wringer will be found to serve the pur- pose admirably. Cotton batting, as pur- chased, ordinarly occurs in rolled sheets; if care be taken in the above manipulation, the product can be made to retain this "sheet" form. Medicated Cottons. — These are pre- pared by impregnating good absorbent cotton by means of immersion in liquid containing the medicating substance. Sorrfetimes a large excess of liquid is employed for impregnation, the excess being removed by subsequent expres- sion; or else only so much is used as that when the whole is taken up by the cotton, the latter will contain the requi- site or prescribed amount of medica- ment. In the former case, the expres- sion may be by means of an instrument like an ordinary clotheswringer, con- ducting the expression so that the liquid which the cotton is allowed to retain will yield a proper strength of finished product. In either case, therefore, the result is identical, and while preference is usually given, in the formulas which , follow, to the use of a large amount of liquid, the other process may be substi- tuted, the result always depending more on the care and skill of the operator than on any other circumstances. In impregnating cotton, it may be necessary to knead the latter with the liquid, and sometimes even to macerate for one or two hours ; if the small quantity of liquid be used, then the cotton must be weighted down in some convenient man- ner. In expressing cotton after im- pregnating in a large quantity of liquid, it may be advisable to wrap the cotton in parchment paper to protect it from the press ; if salicylic acid be present, the solution and cotton must not be al- lowed to come in contact with any iron parts. Cotton must always be passed through the press evenly to medicate uniformly. Drying of impregnated cotton may be done on screens either in a drying closet or in a room which is dry and perfectly aseptic or clean. PHARMACEUTICAL PREPARATIONS. 41 Good absorbent cotton, when dipped in water, will take up or retain, after expression, twice its weight of liquid, each pound of dry cotton yielding there- fore three pounds of mpist cotton. All prepared cottons should be kept in suitable receptacles or wrappers such as glass, parchment paper, paraffined paper, paraffined or resin-coated pasteboard boxes, etc., to prevent loss by evapora- tion or accession of septic matter. Cotton, Alembroth. (Sal Alembroth Cotton.) Mercuric chlorid gr. 27 Ammonium chlorid gr. 11 Alcohol fl.oz. g l / 2 Distilled water fl.oz. 40 Absorbent cotton av.oz. 16 Immerse the cotton in the solution and press out to the weight of 48 av. ounces ; dry in the dark.— D. Cotton, Aluminum Acetate. Solution of aluminium ace- tate fl.oz. 16 Distilled water .fl.oz. 32 Absorbent cotton av.oz. 16 Proceed as with borated cotton. This makes a 5 per cent, cotton. For a 10 per cent, cotton of the same kind, use 32 fluidounces of solution and 16 of water for the impregnating solution. — Process of Burow (in D.) : Cotton, Antirheumatic. (Gr i c h t Watte.) I. This article is sometimes called for Germans : Oil of birch tar, rectified, .drops 8 Oil of turpentine, rectified. drops 8 Oil of juniper wood drops 8 Oil of clove drops 8 Oil of rosemary drops 8 Camphor gr. 15 Alcohol fl.dr. 2 Tincture of capsicum fl.dr. 6 Absorbent cotton .-...av.oz. 16 Dissolve the oils and camphor in the alcohol, filter, and moisten the cotton with the filtrate in any convenient way, as, for example, by means of an atom- izer. During this moistening the cotton should be picked into thin layers, and be turned about frequently so as to im- pregnate evenly. Dry by exposure to atmosphere for one hour, and wrap in waxed paper or other suitable con- tainer. — D. II. Red saunders ...... gr. 96 Benzoin gr. 20 Peru balsam gr.,5 Alcohol fl.dr. 8 Macerate for several days, filter and impregnate cotton with filtrate as in the preceding.— H. Modified. Cotton, Benzoated. I. Process of Von Bruns, Jr. (in D.) : 3 per cent. . 4 per cent. Benzoic acid, .av.oz. Y\ av.oz. 1 Castor oil. .. .av.oz. y 2 av.oz. Y* Alcohol, 95 p. c. fl.oz. 58 fl.oz. 58 Absorbent cotton av.oz. 16 av.oz. 16 5 per cent. 10 per cent. Benzoic acid. .av.oz. i 1 /^ av.oz. 2^2 Castor oil. .. .av.oz. 1 av.oz. 1 Alcohol, 95 p. c. fl.oz. 58 fl.oz. 55 Absorbent cotton av.oz.16 av.oz. 16 Dissolve the acid in the alcohol, add the oil, saturate the cotton with this liquid, prepared after any of the given proportions, then press it until it weighs 48 av. ounces, and dry at ordinary tem- perature. II. England's process : Benzoic acid av.oz. 3, gr. 75 Glycerin av.oz. 2 Water, boiling av.lb. 4 Absorbent cotton av.oz. 16 Dissolve the acid in the water, add the glycerin, and the cotton, allow it to soak up all- the liquid, and then dry it. The glycerin is used to prevent crys- tallization of the acid. The product contains 15 per cent, of acid. Cotton, Borated. 5 per cent. Boric acid av.oz. 1 Distilled water, hot fl.oz. 37^ Absorbent cotton av.oz. 16 10 per cent. Boric acid av.oz. 2 Distilled water, hot fl.oz. 36^ Absorbent cotton av.oz. 16 STANDARD FORMULARY OF 20 per cent. Boric acid av:oz. 4 Distilled water, hot fl.oz. 34^ Absorbent cotton av.oz. 16 Dissolve the acid in the water, im- merse the cotton in the solution, press out to the weight of 48 av. ounces, and proceed as with benzoated cotton. — D. See Cotton, Benzoated, No. 1. Cotton, Carbolated. 5 per cent. Carbolic acid, crystal av.oz. i J A Castor oil av.oz. J / 2 Resin av.oz. 5 Alcohol, 95 per cent fl.oz. 50 Absorbent cotton av.oz. 16 10 per cent. Carbolic ^cid, crystal av.oz. 2% Castor oi. fl.oz. 1 Resin av.oz. 7^ Alcohol 95 per cent fl.oz. 47 Absorbent cotton av.oz. 16 Dissolve the resin in the mixed oil and alcohol by agitation, filter, impreg- nate the cotton as before, pressing out to the weight of 48 av. ounces, and dry- ing without heat. Pack immediately in air-tight containers. — Process of Germ. Form, and of Von Bruns, Jr. Cotton, Ichthyol. 20 per cent. Ichthyol av.oz. 5 Alcohol fl.oz. 13^2 Distilled water fl.oz. 32 Absorbent cotton av.oz. 16 50 per cent. Ichthyol av.oz. 12 Alcohol fl.oz. 14 Distilled water fl.oz. 23 Absorbent cotton fl.oz. 16 Dissolve the ichthyol in the alcohol and water, saturate the cotton with the solution, press out to the weight of 48 av. ounces, and dry at a temperature not to exceed 25 degrees C. — D. The ordinary ichthyol (ammonium compound) is to be used for the above. Cotton, Iodized. Iodin gr. 700 Absorbent cotton av.oz. 16 Place the iodin at the bottom of a -wide-mouth glass vial, insert the cotton, tie over the mouth with parchment paper wetted with glycerin, place the vial in a water-bath of from 50 to 60 degrees C, and continue the heat until all of the iodin has been vaporized and the cotton is evenly impregnated with it. Pack in well-closed glass containers. — D. The product is called a 10 per cent, cotton; practically it contains but 9 per cent, of iodin. Cotton, Iodoform. I. Von Mosetig's process (in D.) : 5 per cent. Iodoform av.oz. 1*4 Ether, stronger .fl.oz. 16^2 Alcohol, 95 per cent fl.oz. 44 Absorbent cotton av.oz. 16 10 per cent. Iodoform av.oz. 3 Castor oil av.oz. 1 Resin av.oz. 1 Ether, stronger fl.oz. 33 Alcohol, 95 per cent fl.oz. 36^ Absorbent cotton av.oz. 16 20 per cent. Iodoform av.oz. 6 Castor oil av.oz. 2 Resin av.oz. 2 Ether fl.oz. 53 Alcohol, 95 per cent fl.oz. 12 Absorbent cotton av.oz 16 Dissolve the iodoform in the ether and alcohol, add the resin and castor oil if they be used, agitate until dissolved, saturate the cotton with the solution, wrap in thin parchment paper, puncture a number of holes along the edge, and press out to the weight of 48 av. ounces. This work must be performed with a certain amount of celerity. Dry in the open air, excluding daylight during the entire operation. A better mode of preparation for iodoform cotton is to use only so much solution that, when all is absorbed, the fabric will contain the proper propor- tion. II. England's process: Iodoform gr. 370 Ether fl.oz. n 1 ^ Alcohol fl.oz. 30 T /2 Absorbent cotton av.oz. 16 Dissolve the iodoform in the ether, add the alcohol, impregnate the cotton PHARMACEUTICAL PREPARATIONS. 43 with this liquid so as to take up the whole volume, and then dry it. The product contains 5 per cent, of iodoform, but can be made stronger if desired. Cotton, Iodol. Iodol av.oz. 2 Glycerin av.oz. iY 2 Alcohol fl.oz. 42 Absorbent cotton av.oz. 16 Dissolve the iodol in the alcohol with the aid of a gentle heat (50 degrees C), gradually add the glycerin, saturate the cotton with the solution, kneading thor- oughly, and proceed as described under iodoform cotton, pressing out to 48 av. ounces. The product is a 10 per cent, cotton. A 5 per cent, cotton may be prepared by using a solution composed of 1 av. ounce of iodol, Y\ av. ounce of glycerin and 45 fluidounces of alcohol. — D. Cotton, Mercuric Chlorid. (Sublima- ted or Corrosive Sublimate Cot- ton.) I. Schede's process (in D.) : Y4. and y 2 per cent. Mercuric chlorid gr. 27 or 54 Glycerin av.oz. 5 Alcohol fl.oz. 1^/2 Distilled water fl.oz. 32 Absorbent cotton av.oz. 16 Dissolve the corrosive sublimate in the mixed liquids, filter, and impregnate the cotton as in the preceding, express the cotton until it weighs 48 av. ounces, and dry in the dark at a temperature of about 25 to 30 degrees C. A 1 in 1000 cotton may be prepared by using 11 gr. of mercuric chlorid. II. Link and Voswinkel's process (in D.): J4 per cent. Mercuric chlorid gr. 27 Lithium chlorid gr. 27 Alcohol fl.oz. igY 2 Distilled water fl.oz. 32 Absorbent cotton av.oz. 16 y 2 per cent. Mercuric chlorid gr. 54 Lithium chlorid gr. 54 Alcohol fl.oz. 19^2 Distilled water fl.oz. 32 Absorbent cotton av.oz. 16 Proceed as before and press out to the weight of 48 av. ounces ; dry at a temperature of 25 to 30 degrees C. A 1 in 1000 cotton may be prepared by using 11 gr. each of mercuric and lithium chlorids. Ordinarily sublimated cotton suffers diminution in strength due to reduction of the mercuric chlorid. This is as- cribed to lack of care in preparing the absorbent cotton used, the presence of glycerin and of stearic acid to impart a brilliant whiteness, and creaking sound when pressed between the fingers, etc. The second process is supposed to yield a permanent product. The lithium chlorid is intended to replace the glycerin of other processes. The formula of the Germ. Form, dif- fers from first one of the above only in that 55 fluidounces of alcohol is em- ployed instead of the mixture of alcohol and water. III. England's process (modification of Ruemmel's) : Mercuric chlorid gr. 39 Alcohol .fl.oz. 2^ Glycerin av.oz. 2 Distilled water av.lb. 4 Absorbent cotton av.oz. 16 Dissolve the chlorid in the alcohol, add the cotton, impregnate the cotton with all the liquid, and dry it. The product contains y 2 per cent, of mercuric chlorid. A 1 in 1000 cotton may be prepared by using 8 gr. of mer- curic chlorid. IV. With tartaric acid, T /i per cent, (in D.): Mercuric chlorid gr. 27 Tartaric acid av.oz. ^4 Alcohol fl.oz. 28^ Distilled water fl.oz. 24 Absorbent cotton av.oz. 16 Proceed according to the usual mode, press out to the weight of 48 av. ounces, and dry under exclusion of daylight. V. Lister's sero-sublimate or mercury albuminate cotton, y 2 per cent, (in D.) : Mercuric chlorid gr. 54 Horseblood serum av.oz. 12^ Distilled water fl.oz. 36 Absorbent cotton av.oz. 16 41 STANDARD FORMULARY OF Dissolve the corrosive sublimate by trituration in the blood serum, add the water, and saturate the cotton with the liquid ; press out to 48 av. ounces, and dry at a temperature of 25 to 30 degrees C, light to be excluded. If horseblood serum cannot be had, dissolve 52 gr. of corrosive sublimate and 210 gr. of sodium chlorid, by tritu- ration with 134 av. ounces of egg albu- men diluted with 45 fluidounces of dis- tilled water, and with this prepare the cotton as before. Instead of the horseblood serum, there may be used dried albumen from blood which is now commercially avail- able. One-tenth as much of this as of serum should be employed, to be dis- solved in 9 times its quantity of water. This cotton contains mercury in the form of albuminate. Cotton, Resorcin. 3 per cent. Resorcin av.oz. 1 Glycerin av.oz. 1% Alcohol fl.oz. 23 Distilled water fl.oz. 42^ Absorbent cotton av.oz. 16 5 per cent. Resorcin av.oz. 1% Glycerin av.oz. 1*4 Alcohol fl.oz. 16^ Distilled water fl.oz. 32 Absorbent cotton av.oz. 16 Proceed in the usual manner, pressing out to the weight of 48 av. ounces ; dry at a temperature between 25 and 30 de- grees C. — D. Cotton, Salicylated. I. Process of Von Bruns, Jr. (in D.) : 5 per cent. Salicylic acid av.oz. ^ Castor oil av.oz. l / 2 Alcohol, 95 per cent fl.oz. 34 Absorbent cotton av.oz. 16 10 per cent. Salicylic acid av.oz. i l / 2 Castor oil av.oz. 1 Alcohol, 95 per cent fl.oz. 33 Absorbent cotton av.oz. 16 Dissolve the acid in the alcohol, add the oil, and proceed in the usual way, pressing out to the weight of 48 av. ounces; dry at a temperature between 25 and 30 degrees C. II. Thiersch's process (in D.) : 4 per cent. Salicylic acid av.oz. 1 Glycerin gr. 75 Alcohol fl.oz. S l / 2 Distilled water, hot fl.oz. 40 Absorbent cotton av.oz. 16 10 per cent. Salicylic acid av.oz. 2 l / 2 Glycerin av.oz. x /2 Alcohol fl.oz. 16 Distilled water, hot fl.oz. 32 Absorbent cotton av.oz. 16 Dissolve the acid in alcohol, add the glycerin and water, and proceed as be- fore. A 5 per cent, cotton may be prepared by using the first of the quantities given but increasing the acid to i l /i av. ounces. III. England's process modified : Salicylic acid av.oz. 2 Glycerin av.oz. 2 Alcohol fl.oz. 20 Distilled water, hot fl.oz. 16 Absorbent cotton av.lb. 1 Dissolve the acid in the alcohol, add the glycerin and water, impregnate the cotton with all of the liquid, and dry it. Contact with metals, particularly iron, should be avoided. The product contains 10 per cent, of salicylic acid. Cotton, Styptic. (Hemostatic Cotton. — Ferrated Cotton.) I. Absorbent cotton, Solution of iron chlorid, Glycerin, Water each, sufficient. Mix the liquids in the proportion of 5 parts of the iron solution, 1 part of glycerin, and 14 parts of water by mea- sure, in such quantities that the cotton shall be completely immersed in the liquid when gently pressed. Allow the cotton to remain in the liquid one hour, then remove it, press it until it has been brought to twice its original weight, spread it out in thin layers, in a warm place, protected from dust and light, and when it is sufficiently dry, transfer it to well-closed receptacles. — N. F. PHARMACEUTICAL PREPARATIONS. 45 Solution of ferric chlorid, U. S. P fl.oz. 6H or av.oz. 9M Glycerin fl.oz. 1 or av.oz. ij4 Distilled water fl.oz. 19 Alcohol fl.oz. 19 Absorbent cotton av.oz. 16 Impregnate and press the cotton in the usual manner; dry with exclusion of daylight, and keep the product in amber-colored bottles. — D. III. Solution of iron chlorid (Germ. Pharm. sp. gr. 1.28) fl.oz. 9 Glycerin fl.oz. 1 or av.oz. i}4 Water fl.oz. 19 Alcohol fl.oz. iS'A Absorbent cotton av.oz. 16 Mix the liquids, immerse* the cotton therein, then press it until the product weighs 48 av. ounces, and dry it at a gentle heat, with exclusion of light. — Germ. Form. One hundred parts contain about 25 parts of anhydrous ferric chlorid. Keep the product protected from light. The 9 fluidounces of solution of ferric chlorid of the German pharmacopeia used in the last formula corresponds to 7 fluidounces of the U. S. P. solution. Cotton, Thymol. 2 per cent. 5 per cent, .av.oz. y 2 av.oz. V/± .av.oz. 1 av.oz. 2^4 .av.oz. 7 av.oz. 8 . ..fl.oz. 48 fl.oz. 44 Thymol .... Resin Spermaceti . Alcohol Absorbent cotton av.oz. 16 av.oz. 16 Dissolve the solids in the alcohol, sat- urate the cotton with this solution, the latter being warmed, express to a weight of 48 av. ounces, and spread out to dry. — Ranke's process (in D.). Culture "Fluids. (Nutrient Fluids.) I. Pasteur's for bacteria (in D.) : Ammonium tartrate gr. 35 Potassium phosphate gr. 5 Sugar gr. 700 Distilled water fl.oz. 14^ Dissolve and filter. II. Conn's for bacteria (in D.) : Ammonium tartrate gr. 100 Ammonium acetate gr. 100 Potassium phosphate gr. 5 Magnesium sulfate gr. 3 Calcium chlorid, dry gr. 3 Distilled water fl.oz. 22 Dissolve and filter. III. Miquel's for bacteria (in D.) : Peptone gr. 200 Gelatin gr. 20 Sodium chlorid gr. 50 Potassium carbonate gr. 5 Distilled water fl.oz. 22 Dissolve by aid of heat, and filter. Culture Medium. This is a much-used medium: Agar-agar gm. 7.5 Peptone (Witte) gm. 5 Extract of beef gm. 2.5 Sodium chlorid gm. 2 to 5 Distilled water cc. 500 The ingredients are to be mixed in a porcelain or granite-iron sauce-pan, and boil at a gentle heat until the agar is completely dissolved, care being taken to maintain the exact volume of the mixture by repeated additions of dis- tilled water; remove from the heat, carefully neutralize with a solution of sodium carbonate, and clarify with egg albumen ; finally filter in a funnel pro- vided with a steam or hot-water jacket. In cold weather the proportion of agar may be decreased to 5 grams. The medium while still hot should be poured into sterilized tubes to the depth of about 1)4 inches, the cotton plugs should be replaced, and the tubes be placed in a wire basket and again sterilized as described below for the tubes. On completing the third day's treat- ment, the tubes should be removed while still hot and rotated on a block of ice, holding them horizontally so as to leave a film of the culture medium congealed on the sides. Some tubes may be al- lowed to cool in an inclined position merely, when a thicker stratum of the medium is desired. For the purpose of cultures, test- tubes 6 inches long and tolerably wide diameter may be used. These should first be washed clean, then rinsed with distilled water, the openings closed 4() STANDARD FORMULARY OF tolerably tight with cotton batting (not absorbent cotton), and then sterilized for 4 or 5 hours on three consecutive days. So long as the cotton is not dis- turbed, the interior of the tubes re- mains sterile. Decoctions. (Decocta.) The U. S. P. directs that an ordinary decoction, the strength of which is not directed by the physician, shall be pre- pared according to the following for- mula : The substance, coarsely com- minuted gr. 365 Water, to make fl.oz. 16 Put the substance in a suitable vessel provided with a cover, pour upon it 16 fluidounces of cold water, cover it well, and boil for 15 minutes. Then let it cool to about 40 degrees C, express, strain the expressed liquid, and pass enough cold water through the strainer to make the product measure 16 fluid- ounces. Caution. — The strength of decoctions of energetic or powerful substances should be specially prescribed by the physician. All decoctions should be made in porcelain, porcelain-lined or glass ves- sels. No decoctions are recognized by the present U. S. P. Decoction of Aloes, Compound. (Baume de Vie.) Extract of aloes gr. 72 Myrrh gr. 54 Spanish saffron gr. 54 Potassium carbonate gr. 36 Extract of licorice, powder, .gr. 250 Compound tincture of carda- mom fl.oz. 4 Water, to make fl.oz. 16 Reduce the myrrh and extract of aloes to a coarse powder, mix this with the potassium carbonate and extract of licorice in a suitable covered vessel, and pour on 10 fluidounces of water; boil for 5 minutes, and add the saffron. When cool, add the compound tincture of cardamom, and allow the mixture to macerate for 2 hours ; then filter through flannel, and add enough water to make the product measure 16 fluidounces. This preparation should be freshl) made when required. — N. F. This preparation is original in the Brit. Pharm. The formula of the latest Brit. Pharm. differs from the above in using extract of barbadoes aloes, and in having 36 gr. each myrrh and saffron, 290 gr. of extract of licorice, and 5 fluidounces of compound tincture of cardamom. Decoction of Barley. (Barley Water.) Pearl barley av.oz. 1^2 Distilled water fl.oz. 22 Wash the barley with cold water, and reject the washings; boil the washed barley with the distilled water for 20 minutes in a covered vessel, and strain. The product is about 16 fluidounces. — Brit. Pharm. 1885. Decoction of Broom, Compound. Broom tops gr. 240 Juniper berries gr. 240 Dandelion gr. 240 Distilled water fl.oz. 24 Mix, boil down to 16 fluidounces, and strain. Decoction of Cetraria. (Decoction of Iceland Moss.) Iceland moss gr. 360 Water sufficient. Cover the moss, in a suitable vessel, with 6]/ 2 fluidounces of cold water, let stand for l / 2 hour, and express, throwing the liquid away. Then boil the moss with 16 fluidounces of water for l / 2 hour, strain, and add enough cold water through the strainer to make the colature measure 16 fluid- ounces. — N. F. and U. S. P. 1890. Decoction of Logwood. Logwood, chips gr. 365 Cinnamon, coarse powder... gr. 55 Distilled water, to make. . .fl.oz. 16 Boil the logwood with 16 fluidounces of water for 10 minutes in a closed vessel, adding the cinnamon towards the end of the boiling. Strain and add enough distilled water through the strainer to make 16 fluidounces of cola- ture. PHARMACEUTICAL PREPARATIONS. 47 Contact with iron and other metals should be avoided. — Brit. Pharm. Decoction of Pomegranate Root Bark. (Decoction of Granatum.) I. Pomegranate bark, cut av.oz. 2> l A Distilled water sufficient Add 20 fluidounces of water to the bark, boil for 10 minutes, strain and add, if necessary, enough water through the strainer to make the colature meas- ure 16 fluidounces.— Brit. Pharm. II. Physicians of the Eclectic school are said to use this formula: Drug av.oz. 8 Water gall. 1 Boil the drug well with y 2 of the water, strain through muslin and press well. Boil the residue with the remain- der of the water, strain again. Mix the two liquids and evaporate to 1 pint. — Eclectic. This is used as a tenifuge, the direc- tions being as follows: — The patient should fast for one day and on retiring should take two compound cathartic pills, to be followed in the morning on arising by a good dose of Rochelle salt. As soon as there is profuse stool, he should take 2 or 3 fluidounces of the decoction. If the liquid be retained by the stomach, the worm will probably pass with the next stool. If it be re- jected, as may- be the case, another dose should be given, but not for about 2 hours, to give the stomach a rest. Decoction of Sarsaparilla. Sarsaparilla root oz. 6 Soft water, boiling gall. 1 Macerate the root in the water for 2 hours, then remove the root, bruise, add it again to the liquid, macerate for an- other 2 hours, boil the liquid down to 4 pints, and strain. — Thomsonian (from the Materia Medica). Decoction of Sarsaparilla, Compound. (Decoctum Sarsse Compositum.) I. Sarsaparilla, cut and bruised.gr. 720 Guaiac wood, rasped gr. 145 Sassafras, coarse powder. . . .gr. 145 Licorice root, bruised gr. 145 Mezereum, cut and bruised, .gr. 73 Water, to make fl.oz. 16 Boil the sarsaparilla and guaiac for l / 2 hour in a suitable vessel with 16 fluidounces of water, then add the other ingredients, cover the vessel well, mac- erate for 2 hours, strain, and add enough cold water through the strainer to make 16 fluidounces of product. — N. F. II. Sarsaparilla, cut moderately fine gr. 280 Senna, cut gr. 70 Licorice root, cut gr. 30 Anise, bruised gr. 15 Fennel, bruised gr. 15 Potassa alum gr. 15 Sugar gr. 15 Water sufficient Mix the sarsaparilla with 17 fluid- ounces of water, heat to 35 or 40 deg. C. and maintain at this temperature for 24 hours. Then add the sugar and alum, and expose, in a covered vessel, to the heat of the boiling water bath, for 3 hours, stirring frequently. Now add the senna, anise and fennel, heat for 15 minutes more, strain with ex- pression, allow to stand for a short time, decant the clear liquid from the sediment, and to the former add enough water to make the product weigh 16 av. ounces.— Germ. Pharm. III. Sarsaparilla, Jamaica, cut transversely gr. 910 Sassafras, chips gr. 92 Guaiac wood, rasped gr. 92 Licorice root, bruised gr. 92 Mezereum, cut and bruised.. gr. 92 Distilled water, boiling. .. .fl.oz. 24 Digest the solid ingredients in the water for an hour, boil for 10 minutes in a covered vessel, cool and strain pouring distilled water on the strainer if necessary, to make 16 fluidounces.- Brit. Pharm. 1885. This preparation is not recognized in the Brit. Pharm. 1898, but in its stead is what is called ''concentrated com- pound solution of sarsaparilla," which is 8 times the strength of the above and 48 STANDARD FORMULARY OF from which the above may be prepared by diluting one volume with 7 volumes of water. It is prepared by infusine 16^ av.ounces of Jamaica sarsaparilla, in three successive portions of 5 pints each of distilled water, for one hour each, at 70 deg. C. Boil 730 grains each of sassafras, guaiac wood, licorice root, and mezereum with distilled water un- til exhausted. Rapidly concentrate the mixed infusion and decoction until, when cold, the liquid measures 12^ fluidounces. To this add 3>4 fluidounces of alcohol, set aside for at least 14 days, and filter. The product should measure 16 fluidounces. IV. Thomsonian (from the Materia Medica) : Sarsaparilla root, cut and bruised oz. 6 Sassafras bark oz. 1 Guaiac wood, cut oz. 1 Licorice root oz. 1 Water pints 10 Bruise the drugs, mix with the water, steep over gentle fire for 6 hours, then boil down the liquid to 5 pints, and strain. Diluted alcohol would now be sub- stituted for the high wines. Decoction of Sarsaparilla, Compound Stronger. (Zittmann's Decoction. — Zittmann's Stronger Decoc- tion.) The preparation of 2nd Germ. Pharm. of the above name is the same as that known in the present (3rd) Germ. Pharm. as compound decoction of sar- saparilla. See Decoction of Sarsaparilla, Compound. The formula of the 1st Germ. Pharm. was similar; 18 grains each of sugar and alum were directed, also 12 grains each of anise and fennel, and 35 grains of licorice root. It was further directed, however, in this work that when Decoc- tum Zittmanni is prescribed, it should be prepared in a similar manner except that to the sugar and alum should be added 12 grains of calomel and 3 grains red sulfid of mercury, enclosed in a linen bag. The formula given last is an unsci- entific one, but contains mercury in some form, unless the process has been con- ducted in metallic vessels, and hence is often preferred on this account. Decoction of Sarsaparilla, Comp'd, Weaker. (Zittmann's Weaker or Milder Decoction.) The present (3rd) Germ. Pharm. does not recognize this preparation, but the 2nd and 1st did recognize it. The form- ula of the 2d edition was as follows : Sarsaparilla, cut gr. 140 Lemon peel, cut gr. 15 Cinnamon, bruised gr. 15 Cardamom, bruised gr. 15 Licorice root, cut gr. 15 Water sufficient Macerate the sarsaparilla with 15 fluidounces of water for 24 hours, then heat in a covered vessel on a boiling water bath for 3 hours, stirring occa- sionally; add the other ingredients, mac- erate for 15 minutes, strain the liquid with expression, allow the decoction to settle, pour off the clear liquid, and add enough water to make it weigh 16 av.ounces. The formula of the 1st Germ. Pharm. was slightly different, as follows : Residue from the stronger decoction Sarsaparilla, cut fine gr. 140 Cardamom, bruised gr. 8 Cinnamon, bruised gr. 8 Lemon peel, cut gr. 8 Licorice root, cut gr. 8 Water fl.oz. 17 Mix the residue above specified with the sarsaparilla, and boil the whole with the water in a covered vessel on a steam or boiling water bath for 3 hours. Near the end of this time add the re- maining drugs ; allow to cool, strain, set aside to settle, and decant the clear liquid. The product should weigh about 16 fluidounces. The present Austr. Pharm. recognizes both the stronger and the weaker com- pound decoctions of sarsaparilla. Dilutions, Homeopathic. (Liquid At- tenuations.) The homeopathic process of dilution by means of a progressive scale of 1 part of tincture to 100 parts of vehicle, known as the centesimal scale, was rec- PHARMACEUTICAL PREPARATIONS. 49 ommended by Hahnemann, the father of homeopathy, and adopted by him as the standard. Under this rule, each at- tenuation contained just i/ioo part as much of the drug substance as the pre- ceding attenuation. In order to secure intermediate grades of strength, there has since been introduced the method of diluting in the proportion of I in 10, instead of I in ioo, this constituting the decimal scale. The great advantage of the latter has led to its replacement, to a very great extent, for the centesimal scale. The decimal scale is the only one recognized by the present authority of American homeopathists, the Pharma- copeia of the American Institute of Ho- meopathy, and hence only this one will be recognized in this work. The centesimal scale of dilution or trituration is indicated by numbers af- fixed to the name of the medicament, e. g., belladonna I, belladonna 2, etc., meaning respectively the first centesimal and the second centesimal dilution or trituration. Or the centesimal scale is also indicated by adding "c," viz., bella- donna ic, belladonna 2c, etc. The deci- mal scale is indicated by numbers to which is affixed an "x," viz., belladonna ix, belladonna 2x, etc., so that belladon- na 1 is equal to belladonna 2x. Attenuation or expansion is accom- plished in the process of dilution by the addition of the diluent or vehicle (men- struum) to the liquid or .the solid which is to be attenuated. In the decimal scale the original quan- tity of medicine is diluted progressively by ten so that the first dilution (ix) contains 1/10, the second dilution (2x) contains 1/100, the third dilution (3x) 1/1000, etc., of the original medicine. As solutions and tinctures are to be made, according to the above-mentioned homeopathic standard work, so that 1 part of drug is to be contained in every 10 parts of the diluent, each tincture or solution (with some few exceptions) is equal or equivalent to the first decimal dilution (ix). The exceptions are such sparingly soluble substances as phos- phorus, arsenic, sulfur, etc., which re- quire more solvent, and in such cases the product should contain 1 part of drug in 100 parts, or in 1000 parts, of diluent, dependent on the degree of solu- bility, and this product is therefore the second decimal (2x) or the third deci- mal (3x) dilution. The method of making each dilution, after the original solution or tincture has been prepared, is to take 1 volume of the liquid to be diluted and to add 9 volumes of diluent or vehicle (usually alcohol). The first dilution thus diluted makes the second dilution, the second forms the third, and so on. Dilutions may be made from tritura- tions if desired (a trituration of any strength to make a dilution of the next higher attenuation), provided it is a trit- uration of a substance soluble in alcohol or water. The preferred rule, however, is to use soluble substances for dilu- tions and insoluble substances for tritu- rations. See Triturations. The menstruum to be used in making each dilution will be stated under the respective tincture or solution, which see, in each case, under* Tinctures and Solutions. Discs. (Lamellae.) These are prepared by adding to a concentrated solution of gelatin some glycerin and a solution of a medicating ingredient. While hot this is poured on a perfectly level plate of glass or porcelain, which has previously been very slightly greased, and after drying the discs are cut out from the sheet, each disc to weigh about i/soth to i/30th grain. The discs of the British Pharm. are used only in ophthalmic practice. They are as follows: Discs of Atropine, each containing i/50C0th grain of atropine sulfate. Discs of Cocaine, each containing 1 /50th grain of cocaine hydrochlorid. Discs of Homatropine, each contain- 50 STANDARD FORMULARY OF ing i/iojth grain of homatropine hydro- bromid. Discs of Physostigmine, each contain- ing i/ioooth grain of physostigmine sul- fate. The cocaine discs should weigh about i/30th grain; the others should weigh about i/50th grain. Each disc will be about 1/25 inch in thickness. Disks, Homeopathic. See Medications, Homeopathic. Douche, Nasal. Boric acid gr. 60 Glycerite of tannin fl.oz. i l / 2 Oil of wintergreen drops 10 Water, to make fl.oz. 4 —New York Hospitals. Dressings, Surgical. Descriptions of the methods for pre- paring the various kinds of surgical dressings may be found under the titles Bandages, Plaster Paris; Catgut Liga- tures; Cottons; Flannel; Gauzes; Jutes; Lint ; Oakum ; Silk Ligatures ; Silk Pro- tective; Soap, Surgical; Sponges, Med- icated ; and Wood Wool. Drops. (Guttse.) Preparations popularly known as "drops" vary considerably in character. Some are grouped here, others may be found in other and more appropriate places in this work. Consult the index for the latter. Some of the many popular German and Scandinavian "drops" are mentioned here, but whether the equivalents are always correct is doubtful, as different preparations are dispensed under the same name in different parts of the country of their origin and in different parts of this country. Many of the "drops" are spirits, i. e., alcoholic solutions of volatile oils, for example, "peppermint drops." Drops, Anti-Emetic. Capsicum, powder av.oz. 1 Salt gr. 240 Vinegar fl 07 l6 Water fl.oz. 16 This is to be used in vomiting or nau- sea in doses of a tablespoonful as often as required. — Eclectic. Drops, Bitter. (Beska or Bitre Draa- ber.) For this Scandinavian preparation is to be dispensed compound tincture of wormwood (see Tincture of Worm- wood, Compound) or tincture amara (see Tincture, Bitter, No. IV). Some- times tincture of wormwood is dispensed but the former is the proper "bitre draaber." Drops, Brown. Tannic acid gr. 10 Sodium borate gr. 10 Glycerin fl.dr. 1 Camphor water, to make. . . .fl.oz. 1 Use as eye drops. — New York Hos- pitals. Drops, Camphor. (Kampfer Draaber.) This is the same as Spirit of Ether, Camphorated, which see. Drops, Cholera. Various preparations commonly known by this title will be found under Mix- tures. Drops, Cinnamon. (Kanel Draaber.) For the Scandinavian "Kanel Draa- ber," tincture of cinnamon is to be dis- pensed. The Scandinavian preparation is stronger than the U. S. P., 2> l A av. ounces to be made into 1 pint of tin ture with diluted alcohol. The "Sure Kanel Draaber" (sour chv. namon drops) is tinctura aromatic*, acida, which is practically aromatic sul- furic acid. Drops, Cramp. For Krampf Tropfen it is customary to dispense tincture of valerian or etne- real tincture of valerian, usually the former. For the "red" cramp drop5, also known as Herzstaerkungs Tropfen and Tinctura Apoplectica, one of the follow- ing mixtures may be dispensed : r. Aromatic tincture fl.dr. 4 Tincture of catechu fl.dr. 4 Tincture of cinnamon fl.dr. 4 Red saunders, rasped er. 6a PHARMACEUTICAL PREPARATIONS. 5J Water fl.oz. 2 Alcohol fl.oz. 5 Spirit of ether fl.oz. 7 Macerate for several days, and strain through cotton. — H. II. Oil of peppermint drops 3 Oil of anise drops 5 Oil of cinnamon drops 8 Chloroform fl.dr. y 2 Tincture of catechu fl.oz. 1 Aromatic tincture fl.oz. 2 Water fl.oz. 2 Spirit of ether ...fl.oz. 5 Alcohol fl.oz. 5 l / 2 — H. For the "white" cramp drops, spirit of ether should be dispensed. For the cramp drops of Scandinavians is to be dispensed a mixture of equal parts of solution of ammonium succinate and Hoffmann's drops. Drops, Dysmenorrhea. (Guttee ad. Menstrua Tormentosa, Rade- macher's. Tincture of nux vomica Alcohol Tincture of castor Drops, Family, Yellow. Opium Spanish saffron Castile soap Oil of rosemary. -. Oil of origanum Camphor Alcohol Macerate the opium, saffron and soap with the alcohol for 7 days, agitating occasionally, then add the oils and cam- phor, dissolve, and filter in a well-cov- ered funnel. This is said to be used in some por- tions of the East. Drops, Gold. (Gold Tropfen or Tink- tur. — Golden Tincture. — Tinctura or Essentia Dulcis.) Potassium acetate av.oz. l A Caramel gr Spirit of hydrochloric ether (of ethyl chlorid) fl.oz. Acetic ether fl.dr. Simple syrup fl.oz. Water fl.dr. Alcohol fl.oz. Dissolve the caramel in the water and add the other ingredients. — H. modified. 4 fl.oz . 1 fl.oz 1 fl.oz 2 — H. . . .av.oz. 1 . . .av.oz. iVa . . .av.oz. 8 ....fl.oz. 2/ 2 ....fl.oz. I . . .av.oz. I ....fl.oz. 14^ • gr. 90 1/2 2 1/2 2 12 Sometimes other preparations are dis- pensed for gold drops or golden tinc- ture, such as aromatic or bitter tincture. Spirit of ether is used, so is also com- pound spirit of ether tinted with saf- fron, and also this mixture: Alcohol .fl.oz. 7 l / 2 Ether fl.oz. 7]/ 2 Solution of iron chlorid fl.oz. 1 The ethereal tincture of iron chlorid, N. F., is also known as Lamotte's Gold Drops (or elixir of gold), and this is what may be desired when "gold drops" are requested. Still other formulas which are used are the following: Ether fl.oz. 2 Alcohol fl.oz. 2 Tincture of opium fl.oz. 2 Chloroform fl.oz. 1 Another formula is like the above, but has only ]/ 2 fluidounce of chloro- form. A preparation like either of these lat- ter two must not be dispensed for gold drops or golden tincture unless it is quite certain that such a mixture is wanted. An eclectic preparation called golden tincture is made as follows: Tolu balsam av.oz. ^ Guaiac resin av.oz. *4 Hemlock gum (Canada pitch) av.oz. *4 Myrrh av.oz. % Oil of hemlock fl.dr. 3 Oil of wintergreen fl.dr. 2 Alcohol fl.oz. 16 Reduce the solids to coarse powder, mix all, macerate for 14 days, agitating frequently, and filter. The dose is a teaspoonful. It is rec- ommended for rheumatism, colic, and stomach, pains in the chest or stomach, languor, etc. Drops, Heart-Strengthening. (Herzs- taerkungs Tropfen. — Hjertestyr- kende Draaber.) If asked for by Germans, dispense red cramp drops. See Drops, Cramp. If asked for by Scandinavians, dis- pense a mixture of compound tincture of lavender and spirit of ether. 52 STANDARD FORMULARY OF Drops, Hoffmann's. (Weisse Mutter- krampftropfen.) See Spirit of Ether. Drops, Hoffmann's, Red. For the "red" Hoffmann's drops of Scandinavians, the following is to be dispensed: Oil of amber, rectified m. 15 Oil of clove m. 25 Oil of cinnamon m. 25 Oil of lavender m. 25 Oil of mace m. 25 Peru balsam . gr. 40 Alkanet root gr. 40 Alcohol fl.oz. 1SV2 Mix, macerate for several days, and filter. Drops, Hot. Used in New York Hospitals : Tincture of opium fl.oz. 1 Tincture of capsicum fl.oz. 1 Spirit of camphor fl.oz. I Spirit of peppermint fl.oz. 1 Water fl.oz. 4 See also Tincture of Capsicum and Myrrh. Drops, Jesuit's. (Guttae Jesuitarum.) Guaiac resin, powder av.oz. 3% Sassafras bark, cut av.oz. 2^2 Peru balsam gr. 75 Water fl.oz. 5 Alcohol fl.oz. 13 Mix. macerate for 7 days, agitating occasionally, and filter. — H. Jesuit's Drops is also an old name for Friar's Balsam and for which com- pound tincture of benzoin is now usu- ally dispensed. See Balsam, Friar's, and Tincture of Benzoin, Compound. Drops, Mother. (Mutter Tropfen. — Moder Draaber.) Tincture of cinnamon or of valerian is dispensed as mother drops (when asked for by Germans), also Nos. I or II given under Drops, Cramp, which see. "Red" mother drops is properly aromat- ic tincture. The following is also dispensed as "mother drops" in this country: Crocated tincture of opium, .fl.oz. 4 Fluid extract of valerian. .. .fl.oz. 4 Spirit of ether fl.oz. 8 -pound tincture of zedoary is also used. For the Norwegian "moder draaber," dispense either antihysteric tincture, thebaic tincture of castor, or the follow- ing: Tincture of castor fl.oz. 4 Spirit of ether fl.oz. 4 Tincture of cinnamon fl.oz. 8 Or a mixture of 3 volumes of tincture of cinnamon and 1 of tincture of castor is used. Scandinavians also use a mixture of 1 fluidounce each of camphorated spirit of ether and tincture of castor (Tinc- ture of Castor, No. II) and 10 fluid- ounces of tincture of asafetida. For the "white" mother drops, dis- pense spirit of ether or compound spirit of melissa. Drops, Nerve. See Spirit of Ether, Camphorated. Drops, Pectoral. See Tincture, Pectoral. Drops, Prince's. (Prinsen's Aekta Draaber.) This is Solution of Ammonium Suc- cinate, which see. Drops, Red, Hunter's. Mercuric chlorid gr. 10 Hydrochloric acid drops 12 Compound spirit of lavender fl.oz. 1 Mix and dissolve. — Eclectic. Wine of antimony may be substituted for the compound spirit of lavender. Drops, Rhubarb. (Rhabarber Draa- ber.) The "Rhabarber Draaber" of the Nor- wegian Pharm. is to be prepared as fol- lows : Rhubarb, cut av.oz. 2 Sodium bicarbonate gr. 100 Water fl.oz. 16 Cinnamon water fl.oz. 2^ Macerate the rhubarb and sodium bi- carbonate with the water for 12 hours, strain, and to 13^2 fluidounces of the colature add the cinnamon water. Drops, Stomach. (Bitter Stomachic Drops. — Magen Tropfen.) See Tincture, Bitter, which is dis- pensed for Magen Tropfen or Bittere Magen Tropfen. PHARMACEUTICAL PREPARATIONS. 53 For the so-called Danziger Magen Tropfen is dispensed either compound elixir of orange (compound wine of orange, N. F.) or aromatic tincture. For "white" stomach drops, dispense spirit of ether. Effervescent Salts. See Salts, Effervescent. Electuaries. In conformity to the practice of the U. S. P., these preparations have been placed under "Confections." Elixirs. The presentation of this multitudinous array of elixirs perhaps requires an ex- planation. The catalogues of the large manufacturers list all of the elixirs here- in mentioned, and this fact indicates a demand for them. In order, therefore, that retail pharmacists may supply this demand without recourse to the manu- facturer or the wholesaler, we have giv- en reliable formulas for these prepara- tions. The elixirs of the N. F., U. S. P., and other standard American works are also included. "Elixoid" is a term used to some ex- tent in Great Britain instead of elixir. Under the heading "elixirs," the Na- tional Formulary has the following gen- eral remarks : "The elixirs for which formulas are given in this formulary should, without exception be perfectly clear when dispensed. In most form- ulas ample provision is made for secur- ing preparations that will be, and will remain, satisfactory in this respect. If, however, for any reason an elixir shall become turbid on keeping, it must be filtered through paper or otherwise clari- fied. To secure a brilliantly clear fil- trate it is recommended to shake the turbid elixir with a little purified talc, before filtration, about 3 or 4 drams suf- ficing for 32 fluidounces. While it is manifestly obligatory to use for all medicinal preparations only material of accepted purity and quality, it is worth remembering that no class of preparations calls for greater care in the selection than does that of elixirs and that this is particularly true with regard to the flavoring ingredients (the volatile oils) which must be absolutely fresh and of reliable quality if a satis- factory product is the desideratum. Elixirs should not be exposed to ex- tremes of temperature; they should be kept as near as practicable at the ordi- nary room temperature." Elixir, Adjuvant. I. Fl. ext. of licorice fl.oz. 2 Aromatic elixir fl.oz. 14^2 Mix and filter if necessary. — U. S. P. II. Coriander av.oz. ^2 Caraway av.oz. Yz Sweet orange peel av.oz. 1 Wild cherry av.oz. 2 Licorice root, Russian, peeled av.oz. 4 Simple syrup fl.oz. 20 Alcoh'l, water, each, to make fl.oz. 60 Reduce the wild cherry to a moderate- ly coaise powder, moisten it with 2^/2. fluidounces of water, and set aside for 12 hours. Reduce the other solids also to a moderately coarse powder, mix this intimately with the wild cherry, and having mixed 1 volume of alcohol with 2 of water, moisten the powder with 2^ fluidounces of the mixture, and pack tightly in a percolator. Then gradually pour menstruum on top until 40 fluid- ounces of percolate are obtained. Mix this with the syrup and filter. — N. F. (ist edition.) This preparation is intended as a ve- hicle particularly for acrid or saline rem- edies. Elixir of Acetanilid. This formula may be used : Acetanilid av.oz. 1 Alcohol fl.oz. 5 Glycerin .fl.oz. 4 Tincture of sweet orange peel to make pint 1 Reduce the acetanilid to fine powder and agitate it with the alcohol until dis- solved ; then add the glycerin with 4 fluidounces of the tincture of orange 54 STANDARD FORMULARY OF and make up to 16 fluidounces with the same tincture. Each fluidram contains about 3^ gr. of acetanilid. Elixir of Aletris. (Elixir of Star- grass or Unicorn Root.) Fluid extract of aletris farinosa fl.oz. 2 Simple elixir fl.oz. 14 Mix, let stand for several days, and filter. Each fluidram represents 7^/2 grains of aletris farinosa (unicorn root or star- grass). The formula of the Brit. Form, is as follows : Fluid extract of aletris, Brit. Pharm fl.oz. 4 Liquid extract of licorice, Brit. Pharm fl.oz. 1 Tincture of orange, Brit. Pharm fl.oz. 1 Simple syrup fl.oz. 6 Distilled water, to make fl.oz. 16 Elixir, Aletris, Compound. Aletris (star-grass or uni- corn root) av.oz. 1 Wintergreen av.oz. 1 Catnip av.oz. l /i Cramp bark av.oz. ^2 Blue cohosh av.oz. *4 Cinnamon gr. 60 Bitter orange peel gr. 30 Caraway gr. 15 Sugar av.oz. 5 Alcohol fl.oz. 5 Water, to make fl.oz. 16 Reduce the drugs to moderately coarse powder, and extract by percola- tion in the usual manner, using as men- struum a mixture of the alcohol with an equal volume of water. When this menstruum has passed through the mixed drugs, follow with water until 13 fluidounces of percolate are obtained. In this dissolve the sugar by agitation, add enough water to make 16 fluid- ounces, and filter. — Cine. Acad. Pharm. Several manufacturers make a com- pound elixir of aletris, all of which dif- fer from each other and from the above. Elixir of Aloes, Acid. (Elixir Pro- prietatis Paracelsi.) Aloes, coarse powder av.oz. 1 Myrrh, coarse powder av.oz. 1 Saffron, Spanish, cut fine, .av.oz. Yi Alcohol fl.oz. 15 J4 Diluted sulfuric acid fl.oz. 1 Mix, macerate for 8 days, occasional- ly, and filter. — D. A quick process is to mix 10 fluid- ounces of tincture of aloes and myrrh, 5 of tincture of saffron, and 1 of diluted sulfuric acid. — H. modified. Tincture of aloes and myrrh is usual- ly, but mistakenly, dispensed for elixir proprietatis Paracelsi. Elixir of Aloin, Belladonna and Strychnine, Compound. Aloin gr. 16 Podophyllin gr. 16 Fluid extract of belladonna leaves m. 80 Strychnine sulfate gr. 1^/2 Distilled water fl.dr. 2 Alcohol fl.oz. 2 Simple elixir, to make fl.oz. 16 Dissolve the alkaloidal salt in the wa- ter by the aid of heat, the podophyllin in the alcohol, the aloin in a portion of the elixir, mix all, add the remaining ingredients, and filter if necessary. Each fluidram contains % gr. each of aloin and podophyllin, about 1/80 gr. of strychnine sulfate, and represents about V2 gr. of belladonna leaf. Elixir of Aloin and Strychnine. Aloin gr. 32 Strychnine sulafte gr. 2 Simple elixir fl.oz. 16 Dissolve the alkaloidal salt in the elixir by trituration in a mortar, or agi- tation in a bottle; add the aloin, agitate until dissolved, and filter if necessary. Each fluidram contains yi gr. aloin, and 1/64 gr. strychnine sulfate. Elixir of Aloin, Strychnine and Belladonna. Fluid extract of belladonna root m. 64 Elixir of aloin and strych- nine, to make fl.oz. 16 Each fluidram contains J4 gr. of aloin, and 1/64 gr. of strychnine, and repre- sents Yi gr. of belladonna root. Elixir of Ammonium Bromid. Ammonium bromid gr. 640 Syrup fl.oz. 3 PHARMACEUTICAL PREPARATIONS. 55 Distilled water fl.oz. 8 Aromatic elixir, q. s. Dissolve the ammonium bromid in the distilled water, add the syrup and enough of the elixir to make 16 fluid- ounces, and filter if necessary. — N. F. Elixir of Ammonium Chlorid and Licorice, Compound. Ammonium chlorid ....... .gr. 640 Compound elixir of licorice, to make fl.oz. 16 Dissolve by agitation, and filter if nec- essary. Each fluidram contains 5 gr. of am- monium chlorid. Elixir of Ammonium Valerianate. I. Ammonium valerianate gr. 256 Chloroform m. 10 Tincture of vanilla fl.dr. 2 Compound tincture of cud- bear fl.dr. 2 Ammonia water sufficient Aromatic elixir, to make, .fl.oz. 16 Dissolve the ammonium valerianate in about 1 fluidounce of aromatic elixir, in a graduated vessel, and add enough water of ammonia, in drops, until a faint excess of it is perceptible in the liquid ; then add the chloroform, tincture of vanilla, and compound tincture of cudbear, and finally enough aromatic elixir to make 16 fluidounces. Filter if necessary. — N. F. Each fluidram contains 2 gr. of am- monium valerianate. Should the odor of valerianic acid be- come perceptible after the elixir has been kept for some time, it may be over- come by slightly supersaturating with ammonia water. II. Goddard's formula, modified: Valerianic acid, from the root fl.dr. 3 Ammonium carbonate ....sufficient Distilled water fl.oz. 4 Elixir of curacao fl.oz. 10 Orange flower water fl.oz. 4 Mucilage of gum arabic. .. .fl.oz. 1 Tincture of cudbear fl.dr. 2 Add the acid to the water and neu- tralize with ammonium carbonate ; mix with the other ingredients, and filter. Elixir of Ammonium Valerianate and Chloral Hydrate. Chloral hydrate gr. 640 Elixir of ammonium valeria- nate, to make fl.oz. 16 Dissolve by agitation and filter if nec- essary. Each fluidram contains 5 gr. of chlo- ral hydrate and 2 gr. of ammonium valerianate. Elixir of Ammonium Valerianate with. Cinchonidine. Cinchonidine sulfate gr. 64 Elixir of ammonium valeria- nate, to make fl.oz. 16 Dissolve by agitation. The elixir of ammonium valerianate employed in ma- king this preparation should be exactly neutral. Each fluidram contains Yz gr. of cin- chonidine sulfate and 2 gr. of am- monium valerianate. Elixir of Ammonium Valerianate, Cinchonidine and Iron Pyrophos- phate. Iron pyrophosphate, soluble, .gr. 64 Distilled water, hot .fl.dr. 4 Elixir of ammonium valeria- nate with cinchonidine, to make fl.oz. 16 Dissolve the iron salt in the water and add the elixir of ammonium valerianate with cinchonidine. Each fluidram contains nearly 2 gr. of ammonium and Y2 gr. of cinchonidine sulfate, as well as Y2 gr. of iron pyro- phosphate. Elixir of Ammonium Valerianate with Cinchonidine, Iron Pyro- phosphate and Quinine. Iron pyrophosphate, soluble, .gr. 64 Distilled water, hot fl.dr. 4 Elixir of ammonium valeria- nate^ with cinchonidine and quinine, to make fl.oz. 16 Dissolve the iron salt in the water and add the elixir. Each fluidram contains nearly 2 gr. of ammonium valerianate, Y2 gr. of cincho nidine sulfate, and Y\ gr. of quinine hy- drochlorid, as well as Y gr. of iron pyrophosphate. 56 STANDARD FORMULARY OF Elixir of Ammonium Valerianate with Cinchinidine, Iron Pyro- phosphate, Quinine and Strych- nine. Strychnine sulfate gr. i]4 Distilled water fl.dr. 2 Elixir of ammonium valeria- nate, cinchonidine, iron py- rophosphate, and quinine, to make fl.oz. 16 Dissolve the strychnine salt in the water and add the elixir. Each fluidram contains 2 gr. of am- monium valerianate, J4 gr. each of cin- chonidine sulfate and iron pyrophos- phate, and 1/100 gr. of strychnine sul- fate. Elixir of Ammonium Valerianate with Cinchonidine, Iron Pyro- phosphate and Strychnine. Strychnine sulfate gr. i}4 Distilled water fl.dr. 2 Elixir of ammonium valeria- nate, cinchonidine and iron pyrophosphate, to make. . .fl.oz. 16 Dissolve the strychnine sulfate in the water, and add the elixir. Each fluidram contains nearly 2 gr. of ammonium valerianate, Yi gr. of cin- chonidine sulfate and H gr- of iron py- rophosphate, as well as 1/100 gr. of strychnine sulfate. Elixir of Ammonium Valerianate with Cinchonidine and Quinine. Quinine hydrochlorid gr. 32 Cinchonidine sulfate gr. 64 Elixir of ammonium valeria- nate, enough to make. .. .fl.oz. 16 Mix, dissolve by agitation and filter. Each fluidram contains 2 gr. of am- monium valerianate, ^ gr. of cinchoni- dine sulfate and J4 gr. of quinine hydro- chlorid. Elixir of Ammonium Valerianate with Cinchonidine, Quinine and Strychnine. Strychnine sulfate gr. 1% Distilled water fl.dr. 2 Elixir of ammonium valeria- nate with cinchonidine and quinine, to make fl.oz. 16 Dissolve the strychnine in the water and add the elixir. Each fluidram contains 2 gr. of am- monium valerianate, ]/j gr. of cinchoni- dine sulfate, x /\ gr. of quinine hydro- chlorid and 1/100 gr. of strychnine sul- fate. Elixir of Ammonium Valerianate with Cinchonidine and Strych- nine. Strychnine sulfate gr. 1% Distilled water fl.dr. 2 Elixir of ammonium valeria- nate with cinchonidine, to make fl.oz. 16 Dissolve the strychnine sulfate in the water, add the elixir and filter if neces- sary. Each fluidram contains 1/100 gr. of strychnine sulfate, ^ gr. of cinchonidine sulfate and 2 gr. of ammonium valeria- nate. Elixir of Ammonium Valerianate and Iron. Iron pyrophosphate, soluble, .gr. 128 Distilled water, hot .fl.oz. 1 Elixir of ammonium valeria- nate fl.oz. 15 Dissolve the iron salt in the water and add the elixir. Each fluidram contains 1 gr. of iron pyrophosphate and 2 gr. of ammonium valerianate. Elixir of Ammonium Valerianate with Iron and Quinine. Quinine hydrochlorid gr. 32 Iron pyrophosphate, soluble, .gr. 64 Distilled water, hot fl.dr. 4 Elixir of ammonium valeri- anate, to make fl.oz. 16 Add the quinine salt to 15 fluidounces of elixir, dissolve by agitation, dissolve the iron salt in the water, mix the two solutions, and add the remainder of the water. Each fluidram contains Y gr. of qui- nine hydrochlorid, Y gr. of iron pyro- phosphate and 2 gr. of ammonium vale- rianate. Elixir of Ammonium Valerianate with Iron, Quinine and Strych- nine. Strychnine sulfate gr. iJ4 Distilled water fl.dr. 2 Elixir of ammonium valeri- anate with iron and qui- nine, to make fl.oz. 16 \ Dissolve the strychnine sulfate in the PHARMACEUTICAL PREPARATIONS. water and add the elixir. Each fluidram contains 2 gr. of am- monium valerianate, Ya gr. of quinine hydrochloric!, Yz gr. of iron pyrophos- phate and 1/100 gr. of strychnine sul- fate. Elixir of Ammonium and Morphine Valerianates. Morphine valerianate . .gr. 8 Elixir of ammonium valeri- anate fl.oz. 16 Dissolve by agitation. The elixir of ammonium valerianate used in making this preparation should not be alkaline. Each fluidram contains 1/16 gr. of morphine valerianate and 2 gr. of am- monium valerianate. Elixir of Ammonium Valerianate and Quinine. Quinine hydrochlorid ...gr. 32 Elixir of ammonium valeri- anate, N. F fl.oz. 16 Dissolve the quinine hydrochlorid in the elixir, and filter if necessary. Each fluidram contains Ya gr. of qui- nine hydrochlorid and 2 gr. of ammo- nium valerianate. Elixir of Ammonium, Quinine and Strychnine Valerianates. Strychnine (alkaloid) gr. \Y\ Valerianic acid sufficient Quinine valerianate gr. 64 Elixir of ammonium valeri- anate, N. F., to make fl.oz. 16 Dissolve the strychnine in 2 fluidrams of the elixir of ammonium valerianate by the aid of a slight excess of valeri- anic acid. Triturate the quinine salt with this solution and add the remainder of the elixir of ammonium valerianate, agitate occasionally until dissolved, then filter. In case the valerianic acid is in such excess that its odor is perceptible, the liquid must be cautiously neutralized by stirring it with a glass rod which is re- peatedly moistened with very dilute am- monia water. Any excess of the latter must be avoided, as otherwise alkaloidal strychnine will be precipitated. Each fluidram contains 1/100 gr. of strychnine valerianate, Yz % x - °f quinine valerianate and 2 gr. of ammonium va- lerianate. Elixir of Ammonium Valerianate with Sumbul. (Elixir of Ammo- nium Valerianate with Musk Root.) Fluid extract of sumbul fl.oz. 2 Elixir of ammonium valeri- anate fl.oz. 14 Mix, let stand for several hours and filter through purified talcum. Each fluidram contains nearly 2 gr. of ammonium valerianate and represents 7Y2 gr. of sumbul root. See also No. II under Elixir of Sum- bul, Compound. Elixir of Ammonium Valerianate with Strychnine. Strychnine sulfate gr. i% Distilled water fl.dr. 2 Elixir of ammonium valeri- anate fl.oz. 16 Dissolve the strychnine sulfate in the water by the aid of heat, add the elixir, and filter. The elixir of ammonium valerianate must not be alkaline. Each fluidram contains 2 gr. of ammo- nium valerianate and 1/100 gr. of strych- nine sulfate. Elixir of Anise. (Aniseed Cordial.) Anethol m. 25 Oil of fennel. m. 5 (about, drops 8) Spirit of bitter almond. .. .fl.dr. i l / 2 Distilled water fl.oz. 2 Alcohol fl.oz. 4 Simple syrup fl.oz. 10 Purified talc dr. 2 Mix the anethol, oil and spirit with the alcohol, add the syrup and water, and set the mixture aside for 12 hours. Then mix it intimately with the talc and filter it through a wetted filter, returning the first portions of the filtrate until it runs through clear. — N. F. This elixir is liable to become cloudy, from separation of essential oils, when it is exposed to a temperature lower than that at which it has been filtered. In general, it is recommended that it be cooled to, and filtered at, a temperature of about 15 deg. C. In the northern sections of this country, or in winter STANDARD FORMULARY OF time, it should be cooled to a proportion- ately lower temperature, previous to fil- tration. Anethol is the stearopten of oil of anise, and possesses a finer and purer aroma and taste than any commercial variety of oil of anise. If it cannot be readily obtained, the so-called Saxon oil of anise may be substituted for it. The Russian oil of anise may be used but is not so good as the Saxon. Oil of star-anise, which is usually supplied by wholesalers when "oil of anise" is or- dered, does not answer well for this purpose. The oil of fennel should be from the seed (the so-called "sweet" oil), not that from the chaff. Elixir, Anti-Asthmatic, Hare's. Sodium iodid gr. 256 Sodium bromid gr. 256 Tincture of lobelia fl.dr. 4^4 Fluid extract of euphorbia pilulifera . fl.dr. &/ 2 Spirit of nitroglycerin fl.dr. 1 Distilled water fl.dr. 2 Simple elixir, to make fl.oz. 16 Dissolve the sodium salts in the water, mix the tincture, fluid extract and spirit with 10 fluidounces of elixir, add the solution, and the remainder of the elixir. Each fluidram contains 2 gr. each of sodium iodid and bromid. 2 m. of tinc- ture of lobelia, 3 m. of fluid extract of euphorbia pilulifera and 1/25 m. of ni- troglycerin. Elixir of Arbor Vitse. (Elixir of Thuja Occidentalis.) Fluid extract of arbor vitse.. fl.dr. io>4 Simple elixir, to make fl.oz. 16 Mix, allow to stand for several hours and filter. Each fluidram represents 5 gr. of ar- bor vit?e. Elixir, Aromatic. Compound spirit of orange, .fl.dr. 6 Simple syrup fl.oz. 24 Talc, purified av.oz. 2 Alcohol, deodorized ; distilled water, each, to make fl.oz. 64 To the spirit add enough alcohol to make 16 fluidounces; to this add the syrup in several portions, agitating after each addition, and afterwards add, in the same manner, 24 fluidounces of wa- ter. Mix the talcum with this liquid, agitate viogrously, and filter through a well-wetted filter, returning the first por- tions of the filtrate until a clear liquid is obtained. Lastly, wash the filter with a mixture of 1 volume of alcohol and 3 of water until the product measures 64 fluidounces. — U. S. P. Elixir Aromatic, Red. Cudbear gr. 15 Aromatic elixir fl.oz. 16 Add the cudbear to the elixir, let stand Elixir of Arsenic. (Elixir of Potas- sium Arsenite.) Fowler's solution ' fl.dr. 10^ Simple elixir, to make fl.oz. 16 Each fluidram contains 5 minims of Fowler's solution, which represents 1/20 gr. of arsenous acid. Elixir of Arsenic and Iron Chlorid. See Elixir of Chlorids of Arsenic and Iron. Elixir of Arsenic, Iron and Mercury Chlorids. See Elixir of Chlorids of Arsenic, Iron and Mercury. Elixir of Arsenic, Iron and Quinine. See Elixir of Iron, Quinine and Ar- senic. Elixir of Arsenic and Mercury Iodids. Donovan's solution fl.dr. io^4 Simple elixir, to make fl.oz. 16 Each fluidram contains 1/20 gr. each of red mercuric iodid and arsenic iodid. Elixir of Arsenic and Quinine. Solution of arsenous acid... fl.dr ioy 2 Quinine sulfate gr. 128 Simple elixir, to make fl.oz. 16 Dissolve by agitation and filter if nec- essary. Each fluidram contains 1/20 gr. of ar- senous acid, and 2 gr. of quinine sulfate. Elixir of Arsenic and Strychnine. Solution of arsenous acid... fl.dr 10J/2 Strychnine sulfate gr. 154 Simple elixir, to make fl.oz. 16 Dissolve by agitation and filter. Each fluidram contains 1/20 gr. of ar- senous acid and 1/100 gr. of strychnine sulfate. PHARMACEUTICAL PREPARATIONS. 59 Elixir of Beef. Extract of beef gr. 256 Distilled water fl.oz. 1 Simple elixir, to make fl.oz. 16 Dissolve the extract in the water, add the elixir, let stand for several days if possible, and filter. Each fluidram contains 2 gr. of ex- tract of beef. The extract of beef suitable for this and similar preparations is that which is prepared by Liebig's method. Elixir of Beef, Bismuth, Cinchona and Iron. Extract of beef gr. 256 Distilled water fl.oz. 1 Elixir of bismuth, cinchona . and iron, to make fl.oz. 16 Dissolve the extract in the water, add the elixir, let stand for several days if possible, and filter. Each fluidram contains 2 gr. of ex- tract of beef, 1 gr. of bismuth salt, near- ly 2 gr. of iron, and represents about 1% gr. of calisaya. Elixir of Beef and Cinchona. Extract of beef gr. 256 Distilled water fl.oz. 1 Efetannated elixir of cincho- na to make fl.oz. 16 Dissolve the extract in the water, add the elixir, let stand for several days if possible, and filter. Each fluidram contains 2 gr. of ex- tract of beef and represents about 1^2 gr. of cinchona. Elixir of Beef, Cinchona and Iron. Extract of beef gr. 256 Distilled water fl.oz. 1 Elixir of cinchona and iron, to make fl.oz. 16 Dissolve the extract in the water, add the elixir, allow to stand for several days if possible, and filter. Each fluidram contains 2 gr. of ex- tract of beef and nearly 2 gr. of iron phosphate and represents about i l A gr. of cinchona. Elixir of Beef, Cinchona, Iron and Strychnine. Strychnine sulfate gr. Ij4 Distilled water ..fl.oz. Y* Elixir of beef, iron and cin- chona, to make fl.oz. 16 Dissolve the alkaloidal salt in the wa- ter by the aid of heat, add to the elixir, and filter. Each fluidram contains nearly 2 gr. each of extract of beef and iron phos- phate, 1/100 gr. of strychnine sulfate, and represents about 1*4 gr. of cin- chona. Elixir of Beef, Coca and Iron. Iron phosphate, soluble gr. 256 Extract of beef gr. 256 Distilled water, hot fl.oz. 2 Elixir of coca, to make. . . .fl.oz. 16 Dissolve the iron salt and extract each in 1 fluidounce of water, mix with the elixir, allow to stand for several days, and filter. Each fluidram contains 2 gr. each of iron phosphate and extract of beef and represents about 7 gr. of coca. Elixir of Beef and Iron. Citrate of iron and ammo- nium gr. 128 Distilled water, warm fl.oz. 1 Elixir of beef, to make fl.oz. 16 Dissolve the iron salt in the water and add the elixir. Each fluidram contains 1 gr. of iron salt and about i}4 gr. of extract of beef. Elixir of Beef, Iron and Malt. Extract of beef gr. 256 Extract of malt (thick) . .av.oz. 4 Citrate of iron and ammo- nium gr. 128 Spirit of orange fl.dr. 1 Alcohol fl.oz. 2 Sherry wine fl.oz. 9 Water, Ferric hydrate, each sufficient Dissolve the extract of beef in one fluidounce of hot water, and add the alcohol containing the spirit of orange, then the wine with which the malt ex- tract has previously been mixed ; shake frequently during 2 or 3 days, filter, and wash the filter with a mixture of alcohol and water in the proportion of 1 of the former to 4 of the latter by measure, so as to obtain a filtrate of 15 fluidounces. Dissolve the iron salt in 6 fluidrams of water, add to the filtrate, and then add enough water to make 16 fluidounces. fiO STANDARD FORMULARY OF The ferric hydrate may be prepared as described under elixir of gentian; the amount to be used must be sufficient to detannate the mixture, and if an insuf- ficient amount has been used, more must be added, allowing to stand for several days more. The test to be applied is the usual one — filtering a small amount of liquid and testing the filtrate with solu- tion of iron chlorid to note if any black- ish discoloration occur. Each fluidram contains 2 gr. of extract of beef, 1 gr. of soluble iron citrate and 15 gr. of malt extract. Elixir of Berberine. Berberine phosphate gr. 32 Distilled water, hot fl.oz. 1 Simple elixir fl.oz. 15 Dissolve the berberine in the water and add the elixir. Each fluidram contains %. gr. of ber- berine phosphate. Elixir of Berberine and Iron. Iron pyrophosphate, soluble, .gr. Distilled water, hot fl.oz. Elixir of berberine, to make fl.oz. Dissolve the iron salt in the 128 1 16 water, add the elixir, and filter if necessary. Each fluidram contains 1 gr. of iron pyrophosphate and nearly l / A gr. of ber- berine phosphate. elixir of Bismuth. Glycerite of bismuth fl.oz. 2 Glycerin fl.oz. 2 Distilled water fl.oz. 4 Aromatic elexir fl.oz. 8 Mix in the order given and filter if necessary. Each fluidram contains 2 gr. of bis- muth and sodium tartrate.— N. F. In the former N. F., this preparation was made by dissolving 256 grains of citrate of bismuth and ammonium in 1 fluidounce of hot water by the aid of a few drops of ammonia water, then add- ing enough aromatic elixir to make 16 fluidounces. Elixir of Bismuth, Beef, Cinchona and Iron. Elixir of Beef, Bismuth, Cinchona and Iron. Elixir of Bismuth and Cinchona. Bismuth and ammonium cit- rate gr. 128 Distilled water, hot fl.dr. 4 Ammonia water sufficient Detannated elixir of cincho- na, N. R, to make fl.oz. 16 Mix the bismuth salt with the hot water, allow the solution to stand to permit any undissolved matter to sub- side; decant the clear liquid and add to the residue just enough ammonia water to dissolve. Mix this solution with the decanted liquid, and if alkaline, neu- tralize the mixture with dilute solution of citric acid gradually added. To the whole add the elixir of cinchona, let stand 24 hours, and filter if necessary. Or instead of the above method of preparation, mix 1 fluidounce of glycer- ite of bismuth with 15 of the cinchona elixir. Each fluidram contains 1 gr. of bis- muth salt and represents lYi gr. of cali- saya. Elixir of Bismuth, Cinchona and Iron. Glycerite of bismuth fl.oz. 1 Distilled water fl.oz. 1 Elixir of cinchona and iron. fl.oz. 14 Dilute the glycerite with the water, add the elixir, mix thoroughly, and fil- ter if necessary. — N. F. Each fluidram contains 1 gr. of bis- muth salt and nearly 2 gr. of iron phos- phate. Elixir of Bismuth, Cinchona, Iron and Pepsin. Glycerite of bismuth fl.oz. 1 Detannated tinct. cinchona. fl.oz. 2^ Iron pyrophosphate, soluble.. gr. 256 Pepsin, scale gr. 128 Distilled water fl.oz. 2 Simple syrup fl.oz. 4 Simple elixir, to make. .. .fl.oz. 16 Dissolve the pepsin in 6 fluidounces of simple elixir and the iron salt in the water, then mix all the ingredients, al- low to stand for 24 hours and filter if necessary. Each fluidram represents 1 gr. each of bismuth salt and pepsin, nearly 2 gr. of cinchona and 2 gr. of iron pyrophos- phate. PHARMACEUTICAL PREPARATIONS. 61 Elixir of Bismuth, Cinchona, Iron, Pepsin and Strychnine. Strychnine sulfate gr. V/\ Distilled water, hot. fl.dr. 4 Elixir of bismuth, cinchona, iron and pepsin fl.oz. 15^2 Dissolve the strychnine sulfate in the water, add the elixir, and filter. Elixir of Bismuth, Cinchona, Iron and Strychnine. Strychnine sulfate gr. I % Water, hot fl.dr. 1% Elixir of bismuth, cinchona, and iron, to make fl.oz. 16 Dissolve the strychnine sulfate in the hot water, add the elixir of cinchona, iron and bismuth, and filter, if neces- sary. — N. F. Elixir of Bismuth, Cinchona and Pepsin. Detannated tine, cinchona, .fl.oz. 2 l /2 Glycerite of bismuth fl.oz. 1 Pepsin, scale gr. 128 Distilled water fl.oz. 2 Simple syrup fl.oz. 4 Simple elixir, to make fl.oz. 16 Dissolve the pepsin in the water by agitation, add all the other ingredients, shake thoroughly, allow to stand for 24 hours, and filter if necessary. Each fluidram represents nearly 2 gr. of cinchona and contains 1 gr. each of pepsin and bismuth salt. Elixir Bismuth and Iron. Iron pyrophosphate, soluble.. gr. 128 Distilled water, hot fl.dr. 4 Elixir of bismuth fl.oz. 8 Simple elixir, to make fl.oz. 16 Dissolve the iron salt in water and add the elixirs. Each fluidram contains 1 gr. each of iron pyrophosphate and bismuth salt. Elixir Bismuth, Iron and Pepsin. Glycerite of bismuth fl.oz. 1 Iron pyrophosphate gr. 128 Pepsin, scale gr. 128 Distilled water fl.oz. 3 Simple elixir, to make. .. .fl.oz. 16 Dissolve the iron salt and pepsin each separately in half the water, mix, add all the other ingredients, shake thor- oughly, allow to stand for 24 hours, and filter if necessary. Each fluidram contains 1 gr. each of iron pyrophosphate, pepsin and bismuth salt. Elixir of Bismuth, Iron, Pepsin and Quinine. Quinine hydrochlorid gr. 32 Elixir of bismuth, iron and pepsin fl.oz. 16 Mix, dissolve by agitation, and filter, if necessary. Each fluidram contains 1 gr. each of pepsin, iron pyrophosphate and bismuth salt and l /± gr. of quinine hydrochlorid. Elixir Bismuth, Iron and Quinine. Iron pyrophosphate gr. 128 Quinine hydrochlorid gr. 64 Glyecrite of bismuth fl.oz. 1 Distilled water fl.oz. 2 Simple elixir, to make .... fl.oz. 16 Dissolve the iron and quinine each in 1 fluidounce of water, mix, add the other ingredients, and filter if necessary. Each fluidram contains 1 gr. of iron pyrophosphate, ^ gr. of quinine hydro- chlorid, and 1 gr. of bismuth salt. Elixir of Bismuth, Iron and Strychnine. Iron pyrophosphate, soluble, .gr. 128 Strychnine sulfate gr. 1% Distilled water fl.oz. 1 Elixir of bismuth fl.oz. 8 Simple elixir, to make fl.oz. 16 Dissolve the iron salt and strychnine salt separately in 4 fluidrams of the wa- ter ; add the two elixirs, and filter if necessary. The elixir of bismuth must be perfectly neutral. Each fluidram contains 1/100 gr. of strychnine sulfate and 1 gr. each of iron pyrophosphate and bismuth salt. Elixir of Bismuth, Nux Vomica and Pepsin. Tincture of nux vomica. .. .fl.dr. S X A Elixir of pepsin and bismuth, to make fl.oz. 16 Each fluidram contains nearly 1 gr. of pepsin and 2 gr. of bismuth salt and represents about J / 2 gr. of nux vomica. Elixir of Bismuth and Pancreatin. Glycerite of bismuth fl.oz. 1 Pancreatin, pure gr. 128 Distilled water fl.oz. 1 Simple elixir, to make fl.oz. 16 Mix the pancreatin with the water, agitate occasionally until apparently dis- 62 STANDARD FORMULARY OF solved, add the other ingredients, mix well, and filter. Each fluidram contains I gr. each of pancreatin and bismuth salt. Elixir of Bismuth, Pancreatin and Pepsin. See Elixir of Pancreatin and its com- binations. Elixir Bismuth and Pepsin. Pepsin, scale (1:3000) gr. 64 Glycerin fl.oz. 2 Glycerite of bismuth fl.oz. 2 Distilled water fl.oz. 4 Tinct. of caramel fl.oz. 1 Y2 Aromatic elixir fl.oz. 8 Dissolve the pepsin, the mixed glycerin and distilled water by agitation, then add the glycerite of bismuth and elixir. If decidedly acid, neutralize with solution of sodium hydroxide. Finally add the tincture of caramel and filter. — N. F. Each fluidram contains Y2 gr. of pep- sin and 2 gr. of bismuth and sodium tar- trate. Elixir of Bismuth, Pepsin and Quinine. Quinine hydrochlorid . . .gr. 32 Elixir of pepsin and bis- muth fl.oz. 16 Mix and dissolve by agitation. Each fluidram contains Ya gr. of qui- nine hydrochlorid, Y2 gr. of pepsin, and 2 gr. of bismuth salt. Elixir Bismuth, Pepsin and Strychnine. Strychnine (alkaloid) gr. lY Tartaric acid gr. \Ya Elixir of bismuth and pep- sin fl.oz. 16 Triturate the strychnine and acid with 4 fluidrams of the elixir until dissolved, then add the remainder of the elixir, and filter if necessary. Each fluidram contains about 1/100 gr. of strychnine, Y2 gr. of pepsin, and 2 gr. of bismuth and sodium tartrate. — X. F. Elixir of Bismuth, Pepsin and Wafer Ash. Fluid extract of wafer ash. .fl.oz. 2 Elixir of pepsin and bis- muth fl.oz. 14 Mix, allow to stand 24 hours, and fil- ter through purified talcum. Each fluidram represents 7^ S r - oi wafer ash, nearly 1 gr. of pepsin and nearly 2 gr. of bismuth salt. Elixir of Bismuth and Quinine. Quinine hydrochlorid gr. 32 Elixir of bismuth, to make, .fl.oz. 16 Dissolve the quinine salt in the elixir (which should be neutral) by agitation and filter, if necessary. Each fluidram contains 1 gr. of qui- nine hydrochlorid and 2 gr. of bismuth salt. Elixir of Bismuth and Strychnine. Strychnine sulfate gr. \Y\ Distilled water, hot fl.dr. 4 Elixir of bismuth fl.oz. 15^ Dissolve the alkaloidal salt in the water and add to the elixir, which latter should be neutral. Each fluidram contains 1/100 gr. of strychnine sulfate and nearly 2 gr. of bismuth salt. Elixir, Bitter. (Elixir Amarum.) Extract of wormwood av.oz. 2>Y, Oleosaccharate of pepper- mint av.oz. \Y\ Aromatic tincture fl.oz. \i/i Bitter tincture fl.oz. iYi Water fl.oz. 8^ Triturate the extract and oleosaccha- rate with the water to a smooth condi- tion and add the other ingredients. Al- low the mixture to stand for a short time, then decant the liquid from the sediment. — Germ. Pharm. This preparation should be cloudy and of a dark brown color. Elixir of Blackberry. (Elixir of Rubus.) I. Fluid extract of blackberry root fl.oz. 2 Tincture of vanilla fl.dr. 4 Compound elixir of taraxa- cum fl.oz. 4 Simple elixir, to make fl.oz. 16 Each fluidram represents 7Y2 gr- of blackberry root bark. PHARMACEUTICAL PREPARATIONS. 63 II. Fluid extract of blackberry- root fl.oz. 2 Oil of clove m. 10 Oil of cassia m. 10 Tincture of ginger fl.dr. 4 Simple elixir, to make fl.oz. 16 Elixir of Blackberry, Compound. (Aromatic Elixir of Blackberry.) Blackberry root gr. 120 Galls gr. 120 Cinnamon, Saigon gr. 120 Clove gr. 30 Mace gr. 15 Ginger 15 Syrup blackberry fruit fl.oz. 24 Diluted alcohol sufficient Reduce the solids to a moderately coarse powder, moisten it with diluted alcohol, and percolate it with this men- struum in the usual manner, until 4 fluidounces of percolate are obtained. To this add the syrup of blackberry fruit and mix thoroughly, allow it to stand for several days, and filter. — N. F. Elixir of Black Cohosh. (Elixir of Cimicifuga.) Fluid extract of black co- hosh fl.oz. 4 Alcohol fl.oz. 1 Simple elixir fl.oz. 11 Mix, let stand 24 hours, and filter through purified talcum. Each fluidram represents 7^ gr. of black cohosh. Elixir of Black Cohosh, Compound. (Compound Elixir of Cimicifuga.) Fluid extract of black cohosh fl.dr. 9^ Fluid extract of wild cherry. fl.dr. 8 Fluid extract of bloodroot. fl.dr. 3*4 Fluid extract of licorice. .. .fl.dr. 2>Ya Simple elixir fl.oz. 13 Mix, allow to stand for 24 hours, and filter through purified talcum. Each fluidram represents about 4^ gr. of black cohosh, 4 gr. of wild cherry, and 1^2 gr. each of bloodroot and licor- ice. Elixir of Black Haw. (Elixir of Vi- burnum Prunifolium.) Fluid extract of black haw. fl.oz. 2 Compound tincture of car- damom fl.dr. 10 Aromatic elixir, to make. . .fl.oz. 16 Mix, allow the mixture to stand a few days, if convenient, and filter. Each fluidram represents y]^ gr. of black haw.— N. F. Elixir of Black Haw, Compound. (Compound Elixir of Viburnum Prunifolium.) Fluid extract of black haw.. fl.oz. 2 Fluid extract of hydrastis. . .fl.oz. 2 Fluid extract of Jamaica dogwood fl.oz. 1 Simple elixir fl.oz. 11 Mix, allow to stand for 24 hours, and filter. Each fluidram represents 7^2 gr. each of black haw and golden seal and nearly 4 gr. of Jamaica dogwood. This is listed in manufacturers' cata- logues under the names "Sedative Cor- dial" and "Sedative Elixir." Elixir of Blue Flag. Fluid extract of blue flag. ..fl.oz. 4 Alcohol fl.oz. 1 Simple elixir fl.oz. 11 Mix, allow to stand for 24 hours, and filter. Each fluidram represents 15 gr. of blue flag. Elixir of Blue Flag and Wahoo. Fluid extract of blue flag. ..fl.oz. 2^. Fluid extract of wahoo fl.oz. 2^ Alcohol fl.oz. y 2 Simple elixir fl.oz. 10 Mix, allow to stand for 24 hours and filter through talcum. Each fluidram represents about 10 gr. each of blue flag and wahoo. Elixir of Bromid of Ammonium. See Elixir of Ammonium Bromid. Elixir of Bromid of Caffeine. See Elixir of Caffeine. Elixir of Bromid of Calcium. See Elixir of Calcium Bromid. Elixir of Bromid of Lithium. See Elixir of Lithium Bromid. Elixir of Bromid of Potassium. Potassium bromid gr. 1350 Syrup fl.oz. 3 l / 2 Distilled water fl.oz. 7V 2 Aromatic elixir, q. s. Dissolve the potassium bromid in the distilled water, add the syrup and suffi- cient elixir to make 16 ounces, and filter. 64 STANDARD FORMULARY OF Elixir of Six Bromids. Potassium bromid gr. 640 Sodium bromid gr. 640 Ammonium bromid gr. 384 Calcium bromid gr. 192 Lithium bromid gr. 64 Iron bromid gr. 64 Compound tincture of cud- bear fl.dr. 2 Simple elixir, to make fl.oz. 16 Dissolve by agitation and filter, if necessary. Each fluidram contains 5 gr. each of potassium and sodium bromids, 3 gr. of ammonium bromid, \ l / 2 gr. of calcium bromid, and 1 gr. each of lithium and iron bromids. Elixir of Bromid of Sodium. Sodium bromid gr. 1350 Syrup fl.oz. Z l / 2 Distilled water fl.oz. 7 l / 2 Aromatic elixir, to make, .fl.oz. 16 Dissolve the sodium bromid in the water, add the syrup and sufficient aro- matic elixir to make 16 fluid ounces, and filter.— N. F. Elixir of Bromid of Sodium and Lupulin. See Elixir of Lupulin and Sodium Bromid. Elixir of Three (or Triple) Bromids. Potassium bromid gr. 128 Sodium bromid gr. 128 Elixir of caffeine, to make. fl.oz. 16 Mix, dissolve by agitation, and filter, if necessary. Each fluidram contains 1 gr. of each of the bromids of potassium, sodium and caffeine. Elixir of Bromid of Zinc. Zinc bromid gr. 128 Simple elixir fl.oz. 16 Dissolve by agitation and filter, if necessary. Each fluidram contains 1 gr. of zinc bromid. Elixir of Buchu. Fluid extract of buchu fl.oz. 2 Alcohol fl.oz. 1 Simple syrup fl.oz. 1 Purified talc gr. 120 Aromatic elixir, to make.. fl.oz. 16 Mix the fluid extract of buchu with the alcohol, add the other ingredients. shake well, and if time permits occa- sionally during 12 hours, then filter, re- turning the first portions of filtrate until the liquid passes through clear. Each fluidram represents about yV 2 gr. of buchu. — N. F. Elixir of Buchu, Compound. Compound fl. ext. of buchu. fl.oz. 4 Purified talc gr. 120 Aromatic elixir, to make.. fl.oz. 16 Prepare like elixir of buchu. Each fluidram represents 10 gr. of buchu, and 2 gr. each of cubeb, juniper and uva ursi. — N. F. The process differs from the preceding edition, but the strength is unchanged. Elixir of Buchu and Juniper, Com- pound. (Rheumatic Elixir.) Fluid extract of buchu fl.dr. 6 l / 2 Fluid extract of barberry bark fl.dr. z l A Fluid extract of juniper berries fl.dr. $ l A Sodium salicylate gr. 160 Simple syrup. fl.oz. 1 Alcohol fl.oz. 1 Simple elixir, to make fl.oz. 16 Mix all, let stand for 24 hours, and filter through purified talcum. Each fluidram contains 1*4 g r - of so- dium salicylate, and represents 3 gr. of buchu, and \ l / 2 gr. each of barberry bark and juniper berries. Elixir of Buchu, Juniper and Potassium Acetate. Fluid extract of buchu. .. .fl.dr. 12 Fluid extract of juniper berries fl.dr. 4 Potassium acetate gr. 192 Alcohol fl.oz. 1 Simple syrup fl.oz. 1 Simple elixir fl.oz. 12 Mix, allow to stand for 24 hours and filter through talcum. Each fluidram contains 1^2 gr. of po- tassium acetate, and represents about $y 2 gr. of buchu, and 2 gr. of juniper berries. Elixir of Buchu, Juniper, Uva Ursi and Potassium Acetate. Fluid extract of buchu fl.oz. 2 Fluid extract of uva ursi. . .fl.dr. 11 Fluid extract of juniper berries fl.dr. $ l / 2 Potassium acetate av.oz. i l / 2 Alcohol fl.oz. 1 Simple syrup fl.oz. 1 Simple elixir, to make fl.oz. 16 PHARMACEUTICAL PREPARATIONS. 65 Mix, allow to stand for 24 hours, and filter through purified talcum. Each fluidram contains about 5 gr. of potassium acetate, and represents 7^ gr. of buchu, 5 gr. of uva ursi, and 2^2 of juniper berries. See also Elixir, Diuretic. Elixir of Buchu and Pareira. Fluid extract of buchu fl.oz. 2 Fluid extract of pareira brava fl.oz. 2 Alcohol fl.oz. 1 Simple syrup fl.oz. 1 Simple elixir fl.oz. 10 Mix, allow to stand for 24 hours, and filter through purified talcum. Each fluidram represents 7^ gr. each of buchu and pareira brava. Elixir of Buchu and Pareira, Compound. Fluid extract of buchu fl.dr 8 Fluid extract of juniper berries fl.dr. 4 Fluid extract of pareira brava fl.dr. 2 Fluid extract of stoneroot. .fl.dr. 2 Alcohol fl.oz. 1 Simple syrup fl.oz. 1 Simple elixir . .fl.oz. 12 Mix, allow to stand for 24 hours, and filter through purified talcum. Each fluidram represents about 4 gr. of buchu, 2 gr. of juniper berries, and 1 gr. each of pareira brava and collin- sonia. Elixir of Buchu and Potassium Acetate. Potassium acetate gr. 640 Elixir of buchu, to make. . .fl.oz. 16 Dissolve the potassium acetate in the elixir and filter, if necessary. Each fluidram represents 5 gr. of po- tassium acetate, and about 7^2 gr. of buchu.— N. F. Elixir of Buckthorn. (Elixir of Frangula.) Fluid extract of buckthorn, .fl.oz. 4 Alcohol fl.oz. 1 Compound elixir of taraxa- cum fl.oz. 4 Aromatic elixir fl.oz. 7 Mix them, allow the mixture to stand 48 hours, if convenient, and filter. Each fluidram represents 15 gr. of buckthorn. Elixir of Butyl Chloral Hydrate. See Elixir of Croton Chloral Hydrate and its combinations. Elixir of Caffeine. Caffeine gr. 128 Diluted hydrobromic acid. . ..m. 30 Syrup of coffee fl.oz. 4 Aromatic elixir, to make, .fl.oz. 16 Rub the caffeine in a mortar, with the acid and about 2 fluidounces of aromatic elixir, until solution is effected; then add the syrup, and lastly the remainder of the aromatic elixir. Filter, if neces- sary. Each fluidram contains 1 gr. of caf- feine.- Elixir of Calcium Bromid. Calcium bromid gr. 640 Diluted hydrobromic acid. . . .m. 30 Syrup fl.oz. 3 Distilled water fl.oz. 8 Aromatic elixir Dissolve the calcium bromid in the distilled water to which has been added the diluted hydrobromic acid, add the syrup and sufficient aromatic elixir to make 16 fluidounces. Elixir of Calcium Hypophosphites. Calcium hypophosphite gr. 256 Hypophosphorous acid, 30%. m. 30 Aromatic elixir, to make. . .fl.oz. 16 Dissolve the calcium hypophosphite in 12 fluidounces of aromatic elixir, add the acid and the remainder of the aromatic elixir and filter. Each fluidram contains 2 gr. of cal- cium hypophosphite. — N. F. Elixir of Calcium Iodid. I. Calcium iodid av.oz. 1^2 Simple elixir, to make fl.oz. 16 Dissolve by agitation, and filter. II. Inasmuch as calcium iodid is an unstable compound, it should be pre- pared as needed, and the following for- mula should therefore recieve prefer- ence : Solution of iron iodid, pre- pared without hypophos- phorous acid fl.dr. 13^2 KG STANDARD FORMULARY OF Calcium oxid, C. P av.oz. 2 Distilled water sufficient. Sugar av.oz. z l / 2 Compound spirit of orange, .fl.dr. 2 Alcohol fl.oz. 4 Hydrate the calcium oxid with 6 fluid- ounces of water, add the solution of iron iodid, heat to boiling, allow to stand a few minutes, decant the clear liquid, add to the residue a fresh portion of dis- tilled water, heat again to boiling, decant as before, and repeat the process again until the mixed decantes measure 10 fluidounces ; add the alcohol containing the spirit, let stand for an hour or more, filter, in the filtrate dissolve the sugar by agitation, and strain if necessary. Each fluidram contains 5 gr. of cal- cium iodid. Elixir of Calcium Lactophosphate. Precipitated calcium carb gr. 75 Lactic acid fl.dr. 4 Phosphoric acid fl.dr. 2 Comp. spirit orange fl.dr. \y 3 Syrup fl.oz. 6 Alcohol fl.oz. 3 l A Purified talc dr. 2 l / 2 Distilled water, q. s. Dissolve the precipitated calcium car- bonate in the lactic acid, which has pre- viously been mixed with 3]/ 2 fluidounces distilled water, and then add the phos- phoric acid diluted with 7 fluid drams distilled water. To this add the syrup and then, in divided portions, the mix- ture of alcohol and compound spirit of orange. Add distilled water to make 16 fluidounces, add the talc, and filter. Elixir of Calcium Lactophosphate, Cinchona and Iron. Syrup calcium lactophos- phate fl.oz. 8 Potassium citrate dr. 4 Elixir cinchona and iron, to make fl.oz. 16 Dissolve the potassium citrate in 7 fl. ozs. elixir cinchona and iron, add the syrup and sufficient elixir to make 16 fluid ounces. Elixir of Calcium Phosphate. Calcium phosphate gr. 640 Hydrochloric acid, U. S. P. fl.dr. 5 Water fl.oz. 1 Tincture of cudbear fl.dr. 2 Simple elixir, to make fl.oz. 16 Mix the calcium phosphate with the water, add the acid, dissolve, add the elixir, and then the tincture. Each fluidram contains 5 gr. of cal- cium phosphate. Elixir of Calcium and Sodium Hypo- phosphites with Cinchona. See Elixir of Cinchona and Hypo- phosphites. Elixir of Calcium and Sodium Hypo- phosphites with Malt. Calcium hypophosphite gr. 128 Sodium hypophosphite gr. 128 Distilled water fl.oz. 2 Adjuvant elixir fl.oz. 6 Fluid extract of malt fl.oz. 8 Dissolve the salts in the elixir by tri- turation, filter, and add the malt ex- tract. Each fluidram contains 1 gr. each of the hypophosphites of calcium and so- dium. Elixir of Calcium and Sodium Hypo- phosphites with Tar. Calcium hypophosphite gr. 128 Sodium hypophosphite gr. 128 Distilled water fl.oz. 2 Elixir of tar, to make fl.oz. 16 Dissolve the salts in the water, add the elixir, and filter. Each fluidram contains 1 gr. of each of the hypophosphites. Elixirs of Calisaya. Elixir of calisaya, and its various combinations, will be referred to under the head of Elixir of Cinchona. Elixir of Cascara Sagrada. I. Aromatic fl. ext. cascara sagrada fl.oz. 8 Aromatic elixir fl.oz. 8 Mix them, allow the mixture to stand a few days, if convenient, and filter. Each fluidram represents 30 gr. of cascara sagrada. N. F. PHARMACEUTICAL PREPARATIONS. II. Tincture of orange, Brit. Pharm fl.oz. iH Alcohol fl.dr. 6 Cinnamon water fl.oz. 2*4 Simple syrup fl.oz. 4 l / 2 Fluid extract of cascara sagrada, Brit. Pharm fl.oz. 6 Brit. Form. Elixir of Cascara Sagrada, Com- pound. (Laxative Elixir. — Elixir Purgans.) Aromatic fl. ext. cascara sagrada fl.oz. 4 Fluid extract of senna fl.dr. 10 Fluid extract of butternut, .fl.oz. 1 Aromatic elixir fl.oz. 11^ Mix them, allow to stand a few days, if convenient, and filter. — N. F. See also Elixir, Cathartic, Compound, Nos. I and II. Elixir, Castillon's. Cinchona, coarse powder. .. .gr. 160 Gentian, coarse powder gr. 160 Ipecac, coarse powder gr. 80 Columbo, coarse powder. .. .gr. 80 Cinnamon, coarse powder... gr. 20 Aqueous extract of opium... gr. 20 Diluted alcohol, to make. . .fl.oz. 16 Mix the drugs, and extract by per- colation or other suitable process. Elixir, Cathartic, Compound. Fluid extract of buckthorn. fl.oz. 4 Fluid extract of senna fl.oz. 3 Fluid extract of rhubarb. . .fl.oz. 2 Spirit of peppermint fl.dr. 3^ . Solution of potassa fl.dr. 1 Saccharin gr. 60 Aromatic elixir, to make. . .fl.oz. 32 Dissolve the saccharin in about 20 fluidounces of aromatic elixir previously mixed with the solution of potassa, then add the fluid extracts, the spirit and the remainder of the elixir, mix well, allow to stand for 24 hours, and filter. — N. F. The dose as an aperient is 1 fluidram, as a cathartic, 3 fluidrams. Other cathartic elixirs mentioned in this work are those containing senna, rhubarb, cascara sagrada senna, and aloin and elixir of long life. The following are cathartic elixirs containing cascara sagrada in which the taste of the latter is well disguised : 5 I. Fluid extract of cascara sagrada, bitterless or aro- matic fl.oz. 3 Fluid extract of senna fl.oz. 2 Fluid extract of wahoo fl.oz. 1 Glycerite of licorice fl.oz. 2 Saccharin gr. 60 Aromatic elixir, to make... fl.oz. 16 The bitter taste of the wahoo is well concealed and the elixir is miscible with water. II. Fluid extract of cascara sagrada, bitterless or aro- matic fl.oz. 3 Fluid extract of rhubarb. . .fl.oz. i l / 2 Fluid extract of senna fl.oz. \ l / 2 Glycerite of licorice fl.oz. 2 Saccharin gr. 60 Aromatic elixir, to make fl.oz. 16 Elixir of Celery, Compound. (Elixir Apii Graveolentis Compositum.) Fluid extract of celery seed. fl.oz. 1 Fluid extract of coca fl.oz. 1 Fluid extract of kola. ..... .fl.oz. 1 Fluid extract of black haw. .fl.oz. 1 Alcohol fl.oz. 2 Aromatic elixir, to make. . .fl.oz. 16 Mix the alcohol with 4 fluidounces of aromatic elixir ; to this add the fluid ex- tract of celery in several portions, shak- ing after each addition, and afterwards the other fluid extracts ; finally, add the remainder of the elixir, allow the mix- ture to stand 24 hours, and filter. Each fluidram represents y x / 2 gr. each of celery seed, coca, kola and black haw. Elixir of Celery and Guarana. (Com- pound Elixir of Guarana.) Fluid extract of celery seed. fl.oz. 2 Fluid extract of guarana. . .fl.oz. 2 Aromatic elixir fl.oz. 12 Mix, allow to stand for 24 hours, and filter through talcum. Each fluidram represents y]/ 2 gr. each of celery and guarana. Elixir of Cherries. (Elixir Ceraso- rum.) Ripe, sour cherries, free from stems av.oz. 8 Alcohol fl.oz-. 2 Glycerin fl.oz. 1 Simple syrup sufficient. 68 STANDARD FORMULARY OF Crush the cherries and stones to a pulp, add the alcohol and glycerin, mac- erate for 7 days, press and filter, and to the filtrate add simple syrup enough to make 16 fluidounces. This is used as a vehicle and adju- vant. Elixir of Chirata. Tincture of chirata fl.oz. 4 Simple elixir fl.oz. 12 Each fluidram represents lj4 gr. of chirata. Elixir of Chloral Hydrate. (Elixir of Chloral.) Chloral hydrate, crystal gr. 640 Simple elixir, to make fl.oz. 16 Mix, dissolve by agitation, and filter, if necessary. Each fluidram contains 5 gr. of chloral hydrate. Elixir of Chloral Hydrate and Am- monium Valerianate. See Elixir of Ammonium Valerianate and its combinations. Elixir of Chloralamid. Chloralamid gr. 480 Tincture of cudbear fl.dr. 2 Alcohol fl.oz. 2 Simple elixir, to make fl.oz. 16 Dissolve by agitation and filter if necessary. Each tablespoonful contains 15 gr. of chloralamid. Elixir of Chlorids of Arsenic and Iron. (Elixir of Two Chlorids.) Solution of arsenous acid. . .fl.dr. 10^2 Tincture of citrochlorid of iron fl.dr. s l A Simple elixir fl.oz. 14 Each fluidram contains 1/20 gr. of ar- senous acid (as so-called "chlorid of ar- senic") and about % gr. of iron chlorid. Elixir of Chlorids of Arsenic, Iron and Mercury. (Elixir of Three Chlorids.) Solution of protochlorid of iron m. 48 Mercuric chlorid gr. 1 Solution of arsenous acid m. 50 Compound elixir of quinine, to make fl.oz. 16 Mix, dissolve, and filter. Each fluidram contains % gr. of fer- rous chlorid, 1 128 gr. of mercuric chlorid and 1/256 gr. of arsenous acid (as so-called "chlorid of arsenic"). Elixir of Four Chlorids. (Four Chlorids.) I. This is from Official Formulas of America Hospitals : Mercuric chlorid gr. Y± Solution of arsenous acid, .fl.dr. 2 Tincture of ferric chlorid. . .fl.dr. 6 Diluted hydrochloric acid. . .fl.dr. 4 Syrup of ginger fl.dr. 12 Water, to make fl.oz. 6 Mix, dissolve and filter, if necessary. Each fluidram contains about 1/40 gr. of arsenous acid (as so-called "chlorid of arsenic"), 1/64 gr. of mercuric chlorid, about V± gr. of ferric chlorid, and about 5 minims of diluted hydro- chloric acid. II. Formula of Dr. A. H. Smith: Mercuric chlorid gr. ito 2 Solution of arsenous acid. .. .fl.dr. 1 Tincture of iron chlorid fl.dr. 4 Diluted hydrochloric acid. .. .fl.dr. 4 Simple syrup fl.oz. 3 Water, to make fl.oz. 6 This is powerful alterative in chloro- sis, anemic syphilitic cases, etc. Elixir of Chloroform. Chloroform m. 256 Simple elixir, to make fl.oz. 16 Mix the alcohol and chloroform, and add the elixir. Each fluidram contains 2 minims of chloroform. Elixir of Chloroform, Compound. (Chloroform Paregoric.) Chloroform fl.oz. 3 Tincture of opium fl.oz. 3 Spirit of camphor fl.oz. 3 Aromatic spirit of ammonia. fl.oz. 3 Oil of cassia m. 40 Alcohol, to make fl.oz. 16 Mix the chloroform with the alcohol; then add the oil, aromatic spirit of am- monia, spirit of camphor and tincture of opium. Allow the mixture to stand a few hours, and filter in a well-covered funnel. Each fluidram represents about 1 gr. of opium and about 11 minims of chloro- form. This preparation was proposed by Dr. Hartshorne and is called chloroform PHARMACEUTICAL PREPARATIONS. 69 paregoric in some sections of the coun- try. Elixir of Cinchona Alkaloids. (Elixir of Calisaya. — Compound Elixir of Quinine.) I. Quinine sulfate gr. 30 Cinchonidine sulfate gr. 15 Cinchonine sulfate gr. 15 Compound tincture of cud- bear fl.oz. \ X A Purified talc gr. 240 Aromatic elixir, to make. ..fl.oz. 32 Dissolve the alkaloidal salts in 30 fluidounces of aromatic elixir, add the compound tincture of cudbear and enough aromatic elixir to make 32 fluid- ounces, triturate with the talcum, allow the mixture to stand several hours if convenient, occasionally shaking, then filter through paper, returning the first portions until the filtrate passes per- fectly clear. — N. F. This preparation is sometimes known as "elixir of cinchona from alkaloids." The formula replaces that given for elixir of cinchona in previous editions of the N. F. which was directed to be made from tincture of cinchona and is believed to produce a practical equiva- lent of the older preparation with the advantage of giving no reaction with salts of iron. It also replaces Detan- nated Elixir of Cinchona and Com- pound of Quinine. The formula of the older N. F. in which tincture of cinchona was employ- ed is also here given. II. Tincture of cinchona fl.oz. 5 Simple syrup fl.oz. 4 Glycerin fl.oz. 4 Aromatic elixir fl.oz. 19 Mix the liquids, allow to stand as long as convenient, and filter through a wet- ted filter.— N. F. (1st edition.) Each fluidram represents nearly 2 gr. of yellow cinchona. III. A. B. Taylor's formula: Yellow cinchona gr. 420 Sweet orange peel, recently dried gr. 210 Ceylon cinnamon gr. 105 Coriander gr. 105 Anise gr. 25 Caraway gr. 25 Cardamom gr. 25 Cochineal gr. 25 Brandy fl.oz. 9 Simple syrup fl.oz. 9 Water, alcohol, each, to make fl.oz. 32 Reduce the orange peel to moderately fine powder by contusion in an iron mortar, add the other solids previously reduced to a moderately fine powder, moisten with the brandy, pack in a per- colator, add the remainder of the brandy, then percolate mith a mixture of 1 volume of alcohol and 3 of water so as to obtain 23 fluidounces of perco- late and to the latter add the simple syrup. This is almost identical with Elixir of Cinchona, Compound, which see. IV. Yellow cinchona gr. 480 Sweet orange peel, fresh gr. 480 Cinnamon . .gr. 180 Tincture of cardamon fl.dr. 1 Simple syrup fl.oz. 8 Diluted alcohol, to make... fl.oz. 32 Contuse the orange peel, in an iron mortar, to moderately fine powder, add the other drugs in moderately fine pow- der, extract by percolation with diluted alcohol so as to obtain 24 fluidounces of percolate; to the latter add the syrup. Elixir of Cinchona and Beef. Elixir of Cinchona, Beef and Iron. Elixir of Cinchona, Beef, Iron and Strychnine. For above, see Elixir of Beef and its combinations. Elixir of Cinchona and Bismuth. Elixir of Cinchona, Bismuth and Iron. Elixir of Cinchona, Bismuth, Iron and Pepsin. Elixir of Cinchona, Bismuth, Iron, Pepsin and Strychnine. Elixir of Cinchona, Bismuth, Iron and Strychnine. 70 STANDARD FORMULARY OF Elixir of Cinchona, Bismuth and Pepsin. For above, see Elixir of Bismuth and its combinations. Elixir of Cinchona, Calcium Lacto- phosphate and Iron. See Elixir of Calcium Lactophosphate and its combinations. Elixir of Cinchona and Coca. (Com- pound Elixir of Cinchona.) Fluid extract of cinchona. . .fl. dr. 10 Fluid extract of coca fl.dr. 10 Tincture of cacao fl.oz. 2V2 Simple elixir fl.oz. 11 Mix, and filter if necessary. Each fluidram represents about 4V2 gr. each of cinchona and coca. Elixir of Cinchona, Compound. (Sim's Elixir of Calisaya.) Yellow cinchona av.oz. Vz Sweet orange peel av.oz. Y± Ceylon cinnamon gr. 60 Coriander gr. 60 Cochineal gr. 20 Anise gr. 15 Cardamom gr. 15 Caraway gr. 15 Brandy fl.oz. 5 Simple syrup fl.oz. 5 Diluted alcohol, to make. .. .fl.oz. 16 Mix the drugs, reduce to coarse pow- der and extract by percolation in the usual manner, using the brandy as a first, and diluted alcohol as a second menstruum, until 11 fluidounces of per- colate are obtained. To the latter add the syrup and filter. — Cine. Acad. Pharm. This is almost identical with Elixir of Cinchona No. Ill, which see. Elixir of Cinchona, Detannated. Instead of using a detannated elixir of cinchona, the present N. F. directs that elixir of cinchona from alkaloids (see Elixir of Cinchona) be used but for those who wish to make the detannated elixir the formula of the older N. F. is here given : I. Detannated tinct. cinchona, .fl.oz. 5 iple syrup fl.oz. 4 Glycerin fl.oz. 4 Aromatic elixir fl.oz. 19 Mix the liquids and filter if necessary. Each fluidram represents nearly 2 gr. of yellow cinchona. — N. F. (1st edi- tion.) II. Diehl's formula: Yellow cinchona gr. 480 Curacoa orange peel gr. 320 Coriander gr. 80 Cinnamon gr. 60 Cardamom gr. 30 Anise gr. 20 Cocoa (any good brand) ... .gr. 160 Spirit of orange fl.dr. 3 Sugar av.oz. 10 Purified talcum av.oz y 2 Alcohol, water, each sufficient. Reduce the cinchona, orange peel, spices, and cocoa together to a moder- ately fine powder, extract by slow per- colation with a menstruum, consisting of 1 volume of alcohol with 3 of water so as to obtain 16 fluidounces of perco- late. Prepare hydrate of iron as directed under Detannated Tincture of Cinchona or under Elixir of Gentian, and de- tannate the above percolate as there di- rected, washing the residue, with a mix- ture similar to the menstruum used, until the liquid measures 24 fluidounces. To the latter add the spirit of orange and the talcum, shake well, washing the filter with the same liquid that was used before until the filtrate measures 26 fluidounces. To the filtrate add the sugar, and dissolve by agitation ; strain or filter, if this be necessary. III. Lime process: Yellow cinchona, fine powder gr. 480 Quicklime gr. 360 Slake the lime in the least quantity of water, mix intimately with the bark, moisten with alcohol, pack in a glass percolator, and percolate slowly with alcohol as a menstruum in the usual manner until 8 fluidounces are obtained. The first portions of the percolate must be tested with solution of ferric chlorid ; so long as this liquid affords a discolor- ation it must be returned to the perco- lator. PHARMACEUTICAL PREPARATIONS. :j Prepare flavoring as follows : Oil of orange peel fl.dr 2 Oil of caraway fl.dr. I Oil of cassia fl.dr. I Alcohol fl.oz. i Triturate I fluidounce of this mixture with 60 gr. of purified talcum, Vz fluid- ounce of alcohol and 1 of water, and filter. To 12 fluidounces of simple syrup add 5 gr. of citric acid, previously dissolved in a very small amount of water, and mix this with the percolate, subsequent- ly adding 11 fluidounces of water. Then to this add the flavoring mixture, mix well, and filter the whole. Finally, add through the filter enough of a mixture of equal volumes of diluted alcohol and simple syrup to make 32 fluidounces. The lime takes the part of the ferric hydrate in No. II. IV. Fenner's formula, modified : Yellow cinchona gr. 480 Sweet orange peel, fresh.... gr. 480 Saigon cassia gr. 120 Coriander gr. 120 Red rose petals gr. 120 Nutmeg gr. 40 Star-anise gr. 40 White of one egg, Sugar av.oz. 8 Alcohol fl.oz. 4 Diluted alcohol, water, each sufficient. Mix the cinchona, cassia, coriander, rose nutmeg, and star-anise, reduce to No. 50 powder, and extract by the usual method of percolation, with diluted alco- hol, so as to obtain 16 fluidounces of percolate. To this add the egg-white, previously beaten with a portion of the percolate. Agitate thoroughly, allow to stand for 24 hours, agitating occasional- ly, and then strain. Contuse the orange peel in an iron mortar to coarse powder, macerate with the alcohol for 2 days, agitating occasionally, decant the liquid, pack the residue in a percolator, pass the previously-obtained detannated per- colate through this drug, and when all has passed continue percolation with water until the total percolate measures 24* fluidounces. In this dissolve the sugar by agitation, add the alcoholic de- cantate which was reserved, and then enough of a mixture of equal parts of diluted alcohol and simple syrup to make 32 fluidounces, and filter the whole. The color of this preparation may be heightened by adding compound tinc- ture of cudbear. The original process is here modified by a slight change in the quantities of the drug so as to reduce the preparation to the strength of that of the N. F., and also by a slight change in the men- struum. Of the five formulas here given, it is the least satisfactory because detanna- tion with egg-white is less satisfactory than with ferric hydrate or lime. Elixir of Cinchona, Gentian and Iron Chlorid. Elixir of cinchona fl.oz. 10 Tincture of iron citrochlorid.fi. dr. 2 Fluid extract of gentian. .. .fl.dr. 2 Simple elixir fl.oz. s z A Mix and filter. Each fluidram represents about 1 gr. each of gentian and cinchona and about 1 m. of tincture of iron chlorid. Elixir of Cinchona, Gentian and Iron Malate. Malate of iron ("scales") .. .gr. 128 Extract of gentian gr. 40 Tincture of vanilla fl.dr. 2 Oil of cinnamon drop 1 Water, hot fl.oz. 1 Simple syrup fl.oz. 4 Elixir of cinchona fl.oz. 6 Aromatic elixir, to make. . .fl.oz. 16 Dissolve the iron salt and extract in the water, add the other ingredients and filter. Each fluidram represents about 1 gr. of gentian and */> gr. of cinchona, and contains 1 gr. of iron malate. The malate of iron to be used should not be the ferrated extract of apples, but the pure malate of iron which ap- pears in the scale form. Elixir of Cinchona and Hypophos- phites. Calcium hypophosphite. . . . /.gr. 128 Sodium hypophosphite gr. 128 STANDARD FORMULARY OF Hvpophosphorous acid, 30%. gr. 30 Water fl.oz. \ Elixir of cinchona, to make . fl.oz. 10 Dissolve the hypophosphites in the water, add acid and the elixir of cin- chona, and filter. Each fluidram contains 1 gr. each of the hypophosphites of calcium and so- dium. — N. F. Elixir of Cinchona and Iron. (Fer- rated Elixir of Cinchona or Cali- saya.) Iron phosphate, soluble gr. 256 Water, distilled fl.oz. 1 Elixir of cinchona, to make . fl.oz. 16 Dissolve the iron phosphate in the water, allow the liquid to cool, add the elixir, and filter. Each fluidram contains 2 gr. of iron phosphate. — N. F. Elixir of Cinchona, Iron and Bis- muth. See Elixir Bismuth, Cinchona and Iron. Elixir Cinchona, Iron, Bismuth and Strychnine. See Elixir Bismuth, Cinchona, Iron and Strychnine. Elixir of Cinchona, Iron and Pepsin. Glycerite of pepsin fl.oz. 3 Elixir of cinchona and iron. fl.oz. 12 Mix, allow to stand a few days, if convenient, then filter, if necessary. Each fluidram represents 1 gr. of pep- sin and about 1J/2 gr. of iron phosphate. — N. F. Elixir of Cinchona, Iron and Phosphorus. Spirit of phosphorous fl.dr. 754 Elixir of cinchona and iron. to make fl.oz. 16 Each fluidram contains 1/200 gr. of phosphorus, 2 gr. of iron phosphate, and represents nearly 2 gr. of cinchona. Elixir of Cinchona and Iron "Protoxid." Solution of iron "protoxid' .fLo"". \ X A Glycerin fl.oz. \ l / 2 Elixir of cinchona fl.oz. 13 Mix the solution and the glycerin, and add the elixir. Elixir of Cinchona, Iron and Strychnine. Strychnine sulfate gr. iJ4 Distilled water m. 75 Elixir of cinchona and iron, to make . fl.oz. 16 Dissolve the strychnine sulfate in the water, add the elixir, and filter if neces- sary. Each fluidram contains 1/100 gr. of strychnine sulfate, and about 2 gr. of iron phosphate. — N. F. Elixir of Cinchona and Pepsin. I. Pepsin, pure gr. 128 Hydrochloric acid m. 30 Detannated elixir of cin- chona or elixir of cin- chona, to make fl.oz. 16 Dissolve by agitation and filter, using purified talcum, if necessary. II. Quinine sulfate gr. 16 Cinchonine sulfate gr. 8 Elixir of pepsin fl.oz. 16 Dissolve the alkaloidal salts in the elixir and filter if necessary. Elixir of Cinchona, Pepsin and Strychnine. Quinine sulfate gr. 15 Cinchonine sulfate gr. j 1 /* Cinchonine sulfate gr. 7^2 Strychnine sulfate gr. i]4 Elixir of pepsin, to make, .fl.oz. 16 Dissolve the alkaloidal salts in the elixir, and filter, if necessary. Each fluidram represents small quan- tities of cinchona alkaloids, 1/100 gr. of strychnine sulfate, and 1 gr. of pepsin. Elixir of Cinchona and Strychnine. Strychnine sulfate gr. 1% Detannated elixir of cin- chona fl.oz. 16 Dissolve by agitation. Each fluidram contains 1/100 gr. of strychnine sulfate, and represents nearly 2 gr. of cinchona. Elixir of Cinchonidine. Cinchonidine sulfate gr. 128 Simple elixir fl.oz. 16 Dissolve by agitation, and filter, if J necessary. PHARMACEUTICAL PREPARATIONS. 73 Each fluidram contains I gr. of cin- chonidine sulfate. Elixir of Cinchonidine and Ammo- nium Valerianate. Elixir of Cinchonidine, Ammonium Valerianate and Iron Pyrophos- phate. Elixir of Cinchonidine, Ammonium Valerianate, Iron Pyrophosphate and Quinine. Elixir of Cinchonidine, Ammonium Valerianate, Iron Pyrophosphate and Strychnine. Elixir of Cinchonidine, Ammonium Valerianate and Quinine. Elixir of Cinchonidine, Ammonium Valerianate, Quinine and Strych- nine. Elixir of Cinchonidine, Ammonium Valerianate and Strychnine. For above, see Elixir of Ammonium Valerianate and its combinations. Elixir of Cinchonidine and Iron. Iron pyrophosphate, soluble.gr. 256 Cinchonidine sulfate gr. 128 Distilled water, hot fl.dr. 6 Simple elixir fl.oz. 15 Dissolve the iron pyrophosphate in the water, and the cinchonidine in the elixir; mix the two solutions and filter if necessary. Each fluidram contains 1 gr. of cin- chonidine sulfate and 2 gr. of iron pyro- phosphate. Elixir of Cinchonidine, Iron Phos- phate and Strychnine. See Elixir of Iron Phosphate, Cin- chonidine and Strychnine. Elixir of Cinchonidine, Iron and Strychnine. Make this either by adding 1*4 gr- of strychnine sulfate, dissolved in a small quantity of hot distilled water, to elixir of cinchonidine and iron, or the elixir of iron phosphate, cinchonidine and strychnine may be employed, which see. Elixir of Coca. (Elixir of Erythroxylon.) Fluid extract of coca fl.oz, 2 Alcohol fl.oz. 1 Simple syrup fl.oz. 2 Tincture of vanilla fl.dr. 2 Purified talcum gr. 120 Aromatic elixir, to make.. fl.oz. 16 Mix the fluid extract with the alcohol, syrup and 10^ fluidounces of aromatic elixir, add the purified talcum and in- corporate the latter thoroughly. Let the mixture stand during 48 hours, if con- venient, shaking occasionally ; then filter, add the tincture of vanilla to the filtrate, and pass the remainder of the elixir through the filter. Each fluidram represents 7^2 gr. of coca. Elixir of Coca, Beef and Iron. See Elixir of Beef and its combina- tions. Elixir of Coca and Cinchona. See Elixir of Cinchona and Coca. Elixir of Coca and Guarana. (Com- pound Elixir of Cocoa.) Fluid extract of coca fl.oz. 2 Fluid extract of guarana. .fl.oz. 2 Purified talcum gr. 120 Compound elixir of taraxa- cum fl.oz. 12 Mix the liquids, and thoroughly in- corporate the purified talcum with the mixture; let it stand during 48 hours, if convenient, occasionally agitating, then filter. Each fluidram represents 7^2 gr. each of coca and guarana. Elixir of Coca and Phosphorus. Spirit of phosphorus fl.dr. 15 Elixir of coca, to make fl.oz. 16 Mix and filter if necessary. Each fluidram contains 1/100 gr. of phosphorus and represents 6^2 gr. of coca. Elixir of Codeine. Codeine sulfate gr. 16 Simple elixir fl.oz. 16 Dissolve by agitation. Each fluidram contains Y% S r - oi co- deine sulfate. Elixir of Codeine and Terpin Hydrate. See Elixir Terpin Hydrate and Codeine. : i STANDARD FORMULARY OF Elixir of Corydalis, Compound. (Al- terative Elixir.— C o m p o u n d Elixir of Turkey Corn.) Fluid extract of turkey corn fl.oz. I Fluid extract of stillingia. .fl.oz i Fluid extract of prickly ash bark fl.dr. 4 Fluid extract of blue flag, .fl.oz. i l /2 Alcohol fl.oz. 2 Potassium iodid gr. 360 Aromatic elixir, to make. :fl.oz. 16 Mix the alcohol with the fluid ex- tracts, dissolve the potassium iodid in the mixture, and add the aromatic elixir. Let the mixture stand a few days, if convenient, and filter. Each fluidram contains 3 gr. of potas- sium iodid, and small quantities of the several fluid extracts. — N. F. Elixir of Crampbark, Compound. (Compound Elixir of Viburnum Opulus.) Fluid extract of crampbark. fl.dr. 10 Fluid extract of aletris (uni- corn root) fl.dr. 10 Fluid extract of bethroot. . .fl.oz. 2 l / 2 Compound elixir of taraxa- cum >. . . .fl.oz. 11 Mix, allow to stand a few days, if convenient, and filter. — N. F. Elixir of Croton Chloral Hydrate. (Elixir of Butyl Chloral Hy- drate.) Croton chloral hydrate gr. 256 Alcohol fl.oz. 1 Tincture of cacao fl.oz. 2 Simple elixir, to make fl.oz. 16 Dissolve the croton chloral in the alco- hol, add the tincture and elixir, and filter, if necessary. Each fluidram contains 2 gr. of croton chloral hydrate. Elixir of Croton Chloral Hydrate and Quinine. Quinine sulfate gr. 128 Elixir of croton chloral hydrate fl.oz. 16 Reduce the quinine salt to fine pow- der, add the elixir, dissolve by agitation, and filter, if necessary. Each fluidram contains 1 gr. of quin- ine sulfate and 2 gr. of croton chloral hydrate. Elixir of Curacao. (Curacao Cordial.) Spirit of curacao m. 125 Orris root, fine powder gr. 30 Citric acid gr. 50 Purified talc gr. 120 Alcohol fl.oz. 4 Simple syrup fl.oz. 8 Distilled water, to make. . .fl.oz. 16 Mix the spirit of curacao with the alcohol, add the orris root, talc, and 3 fluidounces of water. Allow the mix- ture to stand 12 hours, occasionally agi- tating; then pour it on a wetted filter, returning the first portions of the filtrate until it runs through clear, and pass enough water through the filter to make the filtrate measure 8 fluidounces. In this dissolve the citric acid, and finally add the syrup. Elixir of Damiana. (Elixir of Tur- nera.) Fluid extract of damiana. .fl.oz. 2]/ 2 Purified talc gr. 120 Alcohol fl.oz. 4 Glycerin fl.oz. 1 Aromatic elixir fl.oz. 8^2 Mix the fluid extract with the alcohol, add the glycerin and elixir. Incorporate the talc thoroughly with the mixture by trituration, allow to stand, with occa- sional agitation, during 24 hours, if convenient, and then filter. Each fluidram represents nearly 10 gr. of damiana. Elixir of Damiana, Iron, Nux Vom- ica and Phosphorus. Fluid extract of damiana. .fl.oz. 2 Tincture of nux vomica. . .fl.dr. 10^ Iron pyrophosphate, soluble.gr. 128 Elixir of phosphorus fl.oz. 4 Alcohol fl.oz. 2 Distilled water, hot fl.dr. 4 Simple elixir, to make. .. .fl.oz. 16 Mix the fluid extract, tincture, elixir of phosphorus, alcohol, and 6 fluidounces of simple elixir, also dissolve the iron salt in the water, mix the two liquids, add the remainder of the simple elixir, and filter, if necessary, in a well-covered funnel. Each fluidram represents 7^ gr. of damiana and about 1 gr. of nux vomica, and contains 1/200 gr. of phosphorus" and 1 gr. of iron pyrophosphate. PHARMACEUTICAL PREPARATIONS. 75 Elixir of Damiana, Iron and Phosphorus. Fluid extract of damiana. .fl.oz. 2 Elixir of phosphorus fl.oz. 4 Iron pyrophosphate, soluble.gr. 128 Alcohol fl.oz. 1 Distilled water, hot fl.dr. 4 Simple elixir, to make fl.oz. 16 Mix the fluid extract, elixir of phos- phorus, alcohol, and 8 fluidounces of simple elixir, dissolve the iron pyro- phosphate in the water, mix the two liquids, add the remainder of the elixir, and filter, if necessary, in a well-covered funnel. Each fluidram contains 1/200 gr. of phosphorus and 1 gr. of iron pyrophos- phate and represents j l / 2 gr. of damiana. Elixir of Damiana, Nux Vomica and Phosphorus. Fluid extract of damiana. . .fl.oz. 2 Tincture of nux vomica. .. .fl.dr. 10^ Elixir of phosphorus fl.oz. 2 Alcohol fl.oz. 2 Simple elixir, to make fl.oz. 16 Mix the above ingredients in the or- der given and filter, if necessary, in a well-covered funnel. Each fluidram represents 1/200 gr. of phosphorus, about 1 gr. of nux vomica, and 7^2 gr. of damiana. Elixir of Damiana and Phosphorus. Elixir of phosphorus fl.oz. 8 Fluid extract of damiana. .. .fl.oz. 2 Alcohol fl.oz. 2 Simple elixir fl.oz. 4 Mix the elixir of phosphorus, alcohol, and fluid extract and add the simple elixir. Each fluidram represents 1/100 gr. of phosphorus and j l / 2 gr. of damiana. Elixir of Damiana, Phosphorus and Strychnine. Elixir of phosphorus fl.oz. 8 Fluid extract of damiana. . .fl.oz. 2 Alcohol fl.oz. 2 Strychnine sulfate gr. i}4 Simple elixir fl.oz. 4 Mix the elixir of phosphorus, alcohol, and fluid extract and add the simple elixir, having first dissolved the alka- loidal salt in the latter. Each fluidram represents 7 l / 2 gr. of damiana and contains 1/100 gr. each of phosphorus and strychnine sulfate. Elixir of Dandelion. Fluid extract of dandelion, .fl.oz. 6 Simple elixir, to make fl.oz. 16 Each fluidram represents 22^2 gr. of dandelion. Elixir of Dandelion, Compound. See Elixir of Taraxacum, Compound. Elixir of Dewberry Boot, Compound. Dewberry root, coarse pow- der av.oz. 2J4 Galls, powder gr. 120 Kino, powder gr. 120 Cinnoman, powder gr. 60 Clove, powder gr. 30 Capsicum, powder gr. 5 Tincture of opium fl.dr. 4 Spirit of peppermint m. 45 Brandy fl.oz. 16 Sugar av.oz. y l / 2 Macerate all of the above, sugar ex- cepted, for 14 days, shaking occasional- ly; express, filter, and in the filtrate dis- solve the sugar. — D. C. Form. Elixir, Digestive, Compound. See Elixir of Pepsin, Compound. Elixir Diuretic. Buchu av.oz. V/^ Juniper berries av.oz. Y^. Cubeb av.oz. ^4 Bitter orange peel gr. 360 Coriander gr. 180 Cassia buds gr. 180 Anise gr. 60 Caraway gr. 60 Cardamom gr. 20 Potassium acetate av.oz. 1^2 Spirit of nitrous ether fl.oz. i l / 2 Sugar av.oz 4 Alcohol, water, each to make fl.oz. 16 Reduce the drugs to moderately coarse powder, extract by percolation in the usual manner with a menstruum com- posed of 1 volume of alcohol and 2 oi water so as to obtain ij l / 2 fluidounces of percolate. Evaporate the latter on a water bath to 11^2 fluidounces, in this dissolve the sugar and potassium ace- tate, when cool add the spirit and enough water to make 16 fluidounces, and filter. — Cine. Acad. Pharm. 76 STANDARD FORMULARY OF Elixir, Emmenagogue. I. Rue gr. 96 Spanish saffron gr. 96 Savin gr. 96 Socotrine aloes gr. 192 Adjuvant elixir, to make. . .fl.oz. 16 Reduce the drugs to moderately fine powder, mix with 12 fluidounces of ad- juvant elixir, macerate for 7 days, agi- tating occasionally, filter, and through the filter add the remainder of the elixir. Each fluidram represents Y\ gr. each of rue, saffron and savin, and ij4 g r - of aloes. II. Fluid extract of blue co- hosh fl.dr. 12^4 Fluid extract of juniper berries fl.dr. 10H Fluid extract of blue flag. . .fl.dr. 4 J A Alcohol fl.oz. 2 Simple elixir, to make fl.oz. 16 Mix and filter. Each fluidram represents 6 gr. of blue cohosh, 5 of juniper berries, and 2 of blue flag. Elixir of Eucalyptus. (Aromatic or Compound Elixir of Eucalyptus.) Fluid extract of eucalyptus. fl.oz. 2 Alcohol fl.oz. 2 Purified talc gr. 120 Syrup of coffee fl.oz. 6 Compound elixir of taraxa- cum fl.oz. 6 Mix the fluid extract with the alcohol, then add the other ingredients, shake the mixture occasionally during 48 hours, if convenient, and filter, Each fluidram represents 7^ gr. of eucalyptus. This preparation is also known as aromatic or compound elixir of eucalyp- tus. Elixir of Eucalyptus, Compound. Eucalyptus leaves av.oz. 2 Licorice root av.oz. 1 Wild cherry av.oz. 1 Sugar av.oz. 5 Compound spirit of orange, .fl.dr. 1 Alcohol, water, each sufficient. Mix the three drugs, reduce them to coarse powder, and extract by percola- tion with a mixture of 1 volume of al- cohol and 2 of water so as to obtain 13 fluidounces of percolate. To this add the spirit and sugar, and dissolve the latter by agitation. This is said to be a good vehicle for disguising the taste of quinine. Elixir Flavoring No. 29. (Elixir Flavoring No. 508.) Oil of sweet orange peel. . . .fl.oz. 4 Oil of caraway seed fl.dr. 2 Oil of coriander fl.dr. 2 Oil of cassia fl.dr. 2 Oil of anise (or oil of nut- meg) fl.dr. 1 Alcohol fl.oz. 15 The oils used must be perfectly fresh. One fluidounce of this flavor is used for 1 gallon of elixir. This flavoring for elixirs is used to some extent and for this reason is here inserted. Elixir of Galls, Aromatic. Nutgall . av.oz. 1 Nutmeg av.oz. */ 2 Cinnamon av.oz. J^ Brandy sufficient. Elixir of orange fl.oz. 10 Reduce the drugs to moderately coarse powder, moisten with brandy, pack in a percolator and percolate until 6 fluid- ounces of liquid are obtained, to which add the elixir. Elixir de Garus. (Elixir Gari. — Aro- matic Elixir.) I. Aloes av.oz. Yi Myrrh av.oz. K Cinnamon gr. 30 Canella gr. 30 Clove gr. 30 Nutmeg gr. 30 Spanish saffron gr. 8 Orange flower water fl.oz. 1 Water fl.oz. 8 Simple syrup fl.oz. 16 Alcohol fl.oz. 16 Reduce the drugs, except the saffron, to a moderately coarse powder, macer- ate for 24 hours in a small still with 8 fluidounces of alcohol and the water, then distil off 8 fluidounces ; to this dis- tillate add the saffron, the remainder of the alcohol and the orange flower water, macerate for 2 days, agitating oc- casionally; add the syrup, and filter. PHARMACEUTICAL PREPARATIONS. 77 [I. Oil of cassia drops 8 Oil of clove .drops 8 Oil of mace drops 8 Saffron gr. 20 Tincture of vanilla fl.dr. V2 t Alcohol fl.oz. 5 Orange flower water fl.oz. 6j4 Sugar av.oz. 7 Mix the oil, saffron, tincture and alco- hol, macerate for 2 days, agitating oc- casionally; strain to remove the saffron, add the orange flower water and sugar, agitate until the latter is dissolved, and filter. — H. modified. Elixir of Gentian. I. Fluid extract of gentian fl.dr. 4 Compound spirit of carda- mom fl.dr. 2 Sodium citrate dr. 4 Glycerin fl.oz. 1 Syrup fl.oz. 5 Alcohol fl.oz. 3 Purified talc dr. 2V 2 Distilled water, q. s. Dissolve the sodium citrate in 6 fluid ounces of distilled water, add this solu- tion to the alcohol with which the com- pound spirit of cardamom has been mixed, then add the fluidextract of gen- tian, the syrup, the glycerin and suffi- cient distilled water to make 16 fluid ounces. Add the purified talc and filter, returning the first portion to the filtrate until it passes through clear. — N. F. Elixir Gentian and Iron. Tinct. ferric citro- chlorid fl.oz. V/ 2 Elixir gentian, to make fl.oz. 16 Mix and filter.— N. F. Each fluidram represents about two grains of gentian. This must not be confused with other elixirs of iron and gentian, or gentian and iron, and particularly with Elixir of Gentian, Fcrrated, the iron salt in this preparation being the phosphate. 11. Extract of gentian gr. 70 Aromatic spirit fl.dr. 3 Tincture of vanilla fl.dr. 2 Simple syrup fl.oz. 1 Aromatic elixir, to make fl.oz. 16 Dissolve the extract in about 2 fluid- ounces of aromatic elixir, add the syrup, spirit, tincture and remainder of the elixir. Filter, if necessary. — N. F. (ist edition.) This is of about the same strength as the preceding. III. This preparation is also made according to one of the formulas for compound elixir of gentian which fol- low. Elixir of Gentian, Compound. I. Stronger compound infusion of gentian fl.oz. 4 Aromatic elixir fl.oz. 12 II. Gentian gr. 256 Coriander gr. 60 Bitter orange peel gr. 60 Compound spirit of orange. fl.dr. 1 Egg albumen gr. 120 Citric acid gr. 5 Sugar '. .av.oz. 5 Alcohol, water, each sufficient Mix the first three ingredients, reduce them to moderately fine powder, and percolate with a mixture of 5 volumes of alcohol and 9 of water until 13 fluid- ounces of percolate are obtained. To this percolate add the albumen and citric acid, agitate until the latter is dissolved, and filter. To the filtrate add the spirit and sugar, agitate until the latter is dis- solved and filter again. — D. C. Form. In the absence of dried egg albumen, the white of 1 egg may be employed. III. Compound tincture of gen- tian fl.oz. 5 Simple elixir fl.oz. 11 Each fluidram represents 2 gr. of gen- tian. Elixir of Gentian, Cinchona and Iron Malate. See Elixir of Cinchona and its com- binations. 78 STANDARD Elixir of Gentian, Ferrated. The X. F. uses this title as a synonym for elixir of gentian and iron phos- phate, but many preparations of this name on the market are made with iron .pyrophosphate instead of the phosphate. See Elixir of Gentian and Iron Phos- phate and Elixir of Gentian and Iron Pyrophosphate. Elixir o? Gentian, Glycerinated. Fluid extract of gentian m. 75 Fluid extract of dandelion, .fl.dr. 2 Acetic ether m. 3° Phosphoric acid, 85% S r - 6 4 Tincture of sweet orange peel fl.dr. 2 Compound tincture of car- damom , fl.oz. 1 Glvcerin fl.oz. 6 l / 2 Sugar av.oz. 354 Sherry wine, to make fl.oz. 16 Dissolve the sugar in 5 fluidounces of wine, add the other ingredients previ- ously mixed, and enough wine to make 16 fluidounces. Allow to stand 24 hours if convenient, and filter. — N. F. Elixir of Gentian and Iron. of citro-chlorid of FORMULARY OF Tincture iron fl.dr. 13 Elixir of gentian, to make.. fl.oz. 16 Mix and filter, if necessary. Each fluidram represents about 24 g r - of ferric chlorid and nearly 2 gr. of gentian. — N. F. Elixir of Gentian and Iron Phos- phate. (Ferrated Elixir of Gen- tian. — Ferrophosphated Elixir of Gentian.) Iron phosphate, soluble gr. 128 Distilled water, hot fl.dr. 4 Elixir of gentian, to make. fl.oz. 16 Dissolve the iron phosphate in the water, add the elixir of gentian, and filter, if necessary. Each fluidram represents I gr. of iron phosphate and nearly 2 gr. of gentian. — •A T . F. Elixir of Gentian and Iron Pyrophosphate. Iron pyrophosphate, soluble.gr. 128 Distilled water, hot fl.dr. 4 Elixir of gentian, to make, .fl.oz. 16 Dissolve the iron salt in the water, add the elixir, and filter, if necessary. Each fluidram contains 1 gr. of iron salt and represents nearly 2 gr. of gen- tian. Elixir of Glycerophosphates Comp. Solution sodium glycero- phosphate dr. 5 Calcium glycerophos dr. 2 Iron glycerophos gr. 24 Soluble manganese glycero . . . gr. 16 Quinine glycerophos gr. 8 Strychnine glycerophos gr. \% Lactic acid fl.dr. 2 l / 2 Comp. spirit cardamom m. 30 Alcohol fl.oz. 2 Glycerin fl.oz. 5 Purified talc dr. 2 l / 2 Distilled water, q. s. Triturate the calcium glycerophos- phate to a smooth paste with 2 fluid ounces glycerin, dissolve the iron and manganese salts with gentle heat in l / 2 ounce distilled water containing l / 2 fl. dr. of the lactic acid. Dissolve the strych- nine and quinine glycerophosphates in \Y\ ounces water, containing the re- mainder of the lactic acid; dissolve the sodium glycerophosphate in y 2 fl. oz. distilled water, hot; and add all solu- tions to the calcium glycerophosphate mixture, mix, add the remainder of the glycerin, the alcohol, the spirit of carda- mom, the talc, water to 16 fl. ozs., and filter.— N. F. Elixir of Glycyrrhizin, Aromatic. Coriander gr. 28 Caraway gr. 28 Cinnamon ..gr. 24 Star-anise gr. 16 Tonka gr. 16 Canella gr. 8 Nutmeg gr. 8 Clove gr. 8 Ammoniated glycyrrhizin. .. .gr. 160 Oil of sweet orange drops 10 Simple syrup fl.oz. 7 Alcohol fl.oz. 6 Water, to make fl.oz. 16 Mix the drugs, and reduce to fine powder. Mix the alcohol with the oil, add 4 l / 2 fluidounces of water, and per- colate the drugs with this menstruum. PHARMACEUTICAL PREPARATIONS. 79 To the percolate add the syrup and the glycyrrhizin dissolved in a small amount of hot water, and if necessary to make a total of 16 fluidounces add sufficient water through the percolator, and add this percolate to the liquid. — Remington's formula. Elixir of Grindelia. Fluid extract of grindelia. .fl.oz. I Compound spirit of orange... m. 75 Alcohol fl.dr. 14 Compound elixir of taraxa- cum fl.oz. 13 Mix them, allow the mixture to stand a few days, if convenient, then filter. Each fluidram represents nearly 4 gr. of grindelia. Elixir of Grindelia, Aromatic. Fluid extract of grindelia. .fl.oz. 4 Canada snakeroot, coarse powder gr. 60 Oil of clove drops 10 Alcohol ._ fl.oz. 3 Simple elixir fl.oz. 9 Dissolve the oil in the alcohol, add the other ingredients, macerate for several days, and filter. Each fluidram represents 15 gr. of grindelia. Elixir of Guaiac. Tincture of guaiac fl.oz. 4 Potassium carbonate gr. 20 Water fl.dr. 2 Glycerin fl.oz. 4 Compound elixir of taraxa- cum fl.oz. 4 Simple syrup fl.oz. 4 Dissolve the potassium carbonate in the water, add to the tincture of guaiac and to this mixture add the remaining ingredients in the order given above. Elixir of Guarana. I. Fluid extract of guarana fl.oz. 3 Aromatic elixir fl.oz. 3 Compound elixir of taraxa- cum fl.oz. 9 Mix them ; allow the mixture to stand during 48 hours, if convenient, and fil- ter.— N. F. Each fluidram represents about 12 gr. of guarana. II. Guarana, powder av.oz. 2> l A Light magnesia gr. 180 Oil of cinnamon drops 5 Simple syrup fl.dr. 13 Diluted alcohol sufficient Sand, clean and coarse. . . .av.oz. 6 l / 2 Mix the guarana and magnesia, moist- en with 2^2 fluidounces of diluted alco- hol, set aside for 24 hours, then mix with the sand, pack in a percolator, per- colate with diluted alcohol until 13 fluid- ounces of liquid are obtained, then re- move the mass from the percolator, in- close it in a cloth and express in a tincture press ; to the percolate add the oil and syrup, and make up to 16 fluid- ounces by addition of the expressed liquid, previously concentrating the lat- ter, if necessary, by evaporation. Each fluidram represents about 11 gr. of guarana. — H. modified and Brit. Form. Elixir of Guarana and Coca. See Elixir of Coca and Guarana. Elixir of Guarana, Compound. (Elix- ir of Guarana and Celery.) See Elixir of Celery and Guarana. Elixir of Helonias. Fluid extract of helonias. . . .fl.oz. 4 Simple elixir fl.oz. 12 Mix, allow to stand for 24 hours and filter. Each fluidram represents 15 gr. of he- lonias. Elixir of Helonias, Compound. (Com- pound Elixir of Squaw-Wine. Compound Elixir of Mitchella. — Helonias Cordial.) Fluid extract of false unicorn (helonias dioica) fl.oz. 1 Fluid extract of blue cohosh. fl.oz. 1 Fluid extract of crampbark. fl.oz. 1 Fluid extract of mitchella. .fl.oz. 2 Purified talcum av.oz. l /> Aromatic elixir, to make fl.oz. 16 Mix and filter. Each fluidram represents 15 gr. of mitchella, and nearly 4 gr. each of helo- nias, blue cohosh and crampbark. Elixir of Hops. Fluid extract of hops fl.oz. 2 Purified talc gr. 120 Tincture of vanilla fl.dr. 4 so STANDARD FORMULARY OF Compound elixir of taraxa- cum fl.oz. 2 Aromatic elixir, to make, .fl.oz. 16 Triturate the fluid extract with the talc, then gradually add the compound elixir of taraxacum, tincture of vanilla, and the aromatic elixir. Allow the mix- ture to stand several days, if convenient, occasionally agitating and then filter. Each fluidram represents 7J/2 gr. of hops. — N. F. Elixir of Hypophosphites. Calcium hypophosphite gr. 384 Sodium hypophosphite gr. 128 Potassium hypophosphite. .. .gr. 128 Hypophosphorous acid, 30%. m. 30 Glycerin fl.dr. 4 Compound spirit of carda- mom fl.dr. 4 Water fl.oz. 7 Aromatic elixir, to make, .fl.oz. 16 Dissolve the hypophosphites and the acid in the water ; then add the glycerin, compound spirit and the aromatic elixir. Filter, if necessary. Each fluidram contains 3 gr. of cal- cium hypophosphite and 1 gr. each of sodium and potassium hypophosphites. — N. F. Elixir of Hypophosphite of Calcium. See Elixir of Calcium Hypophosphite. Elixir of Hypophosphites and Cinchona. See Elixir of Cinchona and Hypo- phosphites. Elixir of Hypophosphites, Compound. The elixir of hypophosphites with iron is sold and dispensed under this name. Elixir of Hypophosphite of Iron. See Elixir of Iron Hypophosphite. Elixir of Hypophosphites with Iron. Calcium hypophosphite gr. 180 Sodium hypophosphite gr. 128 Potassium hypophosphite. .. .gr. 64 Ferric hypophosphite gr. 64 Potassium citrate gr. 85 Hypophosphorous acid, 30%. m. 30 Distilled water fl.oz. 4 Simple syrup fl.oz. 4 Aromatic elixir, to make. ..fl.oz. 16 Dissolve the ferric hypophosphite and potassium citrate in 3 fluidounces of water, and add the syrup. Dissolve the other hypophosphites in the remainder of the water, and mix this with the other solution. Finally add the acid and sufficient aromatic elixir to make the product measure 16 fluid ounces, and filter. Keep the product in dark amber- colored bottles. This process is slightly different from that in the previous edition. Each fluidram contains Vz gr. of iron (ferrous) hypophosphite, 1 gr. each of the hypophosphites of calcium and so- dium, and ^2 gr. of potassium hypophos- phite.— N. F. Elixir of Hypophosphites of Iron and Quinine. I. Iron hypophosphite gr. 128 Potassium citrate gr. 128 Quinine sulfate gr. 128 Calcium hypophosphite gr. 30 Spirit of orange fl.dr. 2 Orange flower water fl.oz. 1 Sugar . . av.oz. 4^ Alcohol, distilled water, each sufficient Dissolve the iron hypophosphite with the aid of the potassium citrate in the orange flower water, and enough water to make the solution measure 6^/2 fluid- ounces, and in this dissolve the sugar. Triturate the quinine sulfate with 5 fluid- ounces of alcohol, add a solution of the calcium hypophosphite in 4 fluidrams of water, and shake the mixture occasion- ally during 1 hour; filter, and wash the filter with enough alcohol to make 7 fluidounces. Add this solution to the spirit of orange, mix this with the iron solution and sugar solution previously prepared, and filter the whole. Each fluidram contains 1 gr. each of the hypophosphites of iron and quinine. II. Solution of iron hypophos- phite fl.dr. 13 Quinine hypophosphite gr. 128 Hypophosphorous acid sufficient Simple elixir, to make fl.oz. 16 Mix the quinine hypophosphite with 8 fluidounces of elixir, add enough of the acid to dissolve the quinine, add the solution of iron hypophosphite, and then PHARMACEUTICAL PREPARATIONS. 81 enough elixir to make 16 fluidounces, and filter. This is of the same strength as the preceding. Elixir of Hypophosphites of Iron, Quinine and Strychnine. This may be prepared by dissolving \ x /\ gr. of strychnine sulfate in 4 fluid- drams of distilled water, and adding enough of the preceding elixir to make 16 fluidounces. . Elixir of Hypophosphites with Malt. See Elixir of Calcium Hypophosphite and its combinations. Elixir of Hypophosphite of Sodium. Sodium hypophosphite gr. 256 Hypophosphorous acid. 30%. .m. 30 Aromatic elixir, to make. . .fl.oz. 16 Dissolve the hypophosphite in about 13 J/2 fluidounces of elixir by agitation, then add the acid and the remainder of the elixir, and filter. Each fluidram contains 2 gr. of sodium hypophosphite. — N. F. Elixir of Hypophosphites with Tar. See Elixir of Calcium Hypophosphite and its combinations. Elixir of Iodids of Arsenic and Mercury. See Elixir of Arsenic and its combi- nations. Elixir of Iodid of Calcium. See Elixir of Calcium Iodid. Elixir of Iodid of Potassium. Potassium iodid gr. 640 Aromatic elixir of licorice, to make fl.oz. 16 Dissolve by agitation. Each fluidram contains 5 gr. of po- tassium iodid. Elixir of Iodid of Potassium, Com- pound. (Alterative Elixir.) Potassium iodid gr. 640 Tincture of citrochlorid of iron fl.dr. 10^ Spirit of orange fl.dr. 4 Fluid extract of saxifrage. fl.dr. 12 Fluid extract of stillingia. .fl.dr. 12 Fluid extract of menisper- mum fl.dr. 12 Fluid extract of helonias. . .fl.dr. 12 Sugar av.oz. 4^ Water, to make fl.oz. 16 Dissolve the potassium iodid in the water, add the tincture of iron, and in this mixture dissolve the sugar by agi- tation. Mix the fluid extracts, add the spirit, then the previously prepared solu- tion, allow the whole to stand for 2 days, and filter. Each fluidram contains 5 gr. of potas- sium iodid, and represents about J / 2 gr. of ferric chlorid, and about S Z A gr. each of saxifraga, stillingia, menispermum and helonias. Elixir of Six Iodids. Arsenic iodid gr. 1 Mercuric iodid gr. 1 Manganese iodid gr. 13 Sodium iodid gr. 128 Potassium iodid gr. 128 Solution of iron iodid m. 15 Sodium hypophosphite sufficient Simple elixir, to make fl.oz. 16 Add the six iodids to the elixir, dis- solve by agitation, add a few grains of sodium hypophosphite, or sufficient to decolorize the liquid, and filter. Each fluidram contains 1/128 gr. each of arsenic and mercury iodids, 1/12 gr. of ferrous iodid, 1/10 gr. of manganese iodid, and 1 gr. each of sodium and po- tassium iodids. Elixir of Iodo-Bromid of Calcium, Compound. (Compound Elixir of Calcium Bromid with Iodids.) Calcium bromid gr. 256 Sodium iodid gr. 256 Potassium iodid gr. 256 Magnesium chlorid gr. 256 Compound fluid extract of sarsaparilla fl.oz. 2 Compound fluid extract of stillingia fl.oz. 2 Aromatic elixir fl.oz. 4 Sugar av.oz. 4 J/2 Water, to make fl.oz. 16 Dissolve the salts in the water add the sugar and to this syrup add the fluid extracts previously mixed with the aro- matic elixir ; after standing for 2 days, filter and add the remainder of the wa- ter. Elixir of Iron Albuminate. Flavored solution of iron albuminate is used as elixir of iron albuminate. Any solution of iron albuminate when con- 82 STANDARD FORMULARY OF taining flavor may be used. See Solu- tion of Iron Albuminate, No. I or II. Elixir of Iron and Ammonium Vale- rianate. See Elixir of Ammonium Valerianate and its combinations. Elixir of Iron and Arsenic, Bitter. (Putzel's Elixir.) Tincture of iron citrochlo- rid fl-oz. 2 Quinine sulfate gr. 128 Strychnine sulfate gr. 1 Sodium arsenate, exsiccated.gr. 1^4 Alcohol fl.dr. 4 Aromatic elixir, to make. . .fl.oz. 16 Mix all but the tincture, dissolve by agitation, add the tincture, and filter. Before the sodium arsenate is weighed a sufficient quantity of it should be powdered and dried at 100 deg. C. un- til it ceases to lose weight. It will then still contain two molecules of water. which cannot be driven out at a tem- perature below 148 deg. C. If a per- fectly crystalline salt, without any trace of efflorescence, is available, this may be used. In this case \Y\ gr. of the crystallized salt should be substituted for the iJ4 gr. of the dried. Each flnidram contains 1 gr. of qui- nine sulfate, 1/128 gr. of strychnine sul- fate, 1/100 gr. of dried sodium arsenate, and 7V2 m. of tincture of iron chlorid. — N. Y. Hosp. Elixir of Iron, Arsenic and Strych- nine. Solution of iron (ferrous) chlorid .....fl.dr. 6 l / 2 Solution of arsenous acid. . .fl.dr. 6H Strychnine sulfate gr. 1^4 Distilled water fl.dr. 4 Solution of arsenous acid, .fl.dr. 6^4 Glycerin fl.oz. 1 Aromatic elixir, to make. . .fl.oz. 16 Mix the ferrous chlorid solution with the glycerin and 4 fluidounces of elixir. To this add the solution of arsenous acid, the strychnine dissolved in the wa- ter by the aid of heat and the remainder of the elixir. Filter if necessary. Each flnidram contains 1 gr. of fer- rous chlorid, 1/32 gr. of arsenous acid and t/too pr of strychnine sulfate. Elixir of Iron and Arsenic Chlorids. Elixir of Iron, Arsenic and Mercury Chlorids. See Elixir of Arsenic and its combina- tions. Elixir of Iron, Beef and Cinchona. Elixir of Iron, Beef, Cinchona and Strychnine. Elixir of Iron, Beef and Coca. Elixir of Iron, Beef and Malt. See Elixir of Beef and its combina- tions. Elixir of Iron and Berberine. See Elixir of Berberine and its combi- nations. Elixir of Iron and Bismuth. Elixir of Iron, Bismuth and Cin- chona. Elixir of Iron, Bismuth, Cinchona and Pepsin. Elixir of Iron, Bismuth, Cinchona, Pepsin and Strychnine. Elixir of Iron, Bismuth, Cinchona and Strychnine. Elixir of Iron, Bismuth and Pepsin. Elixir of Iron, Bismuth, Pepsin and Quinine. Elixir of Iron, Bismuth and Quinine. Elixir of Iron, Bismuth and Strych- nine. See Elixir of Bismuth and its combi- nations. Elixir of Iron, Calcium Lactophos- phate and Cinchona. Elixir of Iron and Cinchona. Elixir of Iron, Cinchona and Pepsin. Elixir of Iron, Cinchona and Strych- nine. See Elixir of Cinchona and its combi- nations. Elixir of Iron Chlorid Tincture and Gentian. See Elixir of Gentian and Iron Chlo- rid Tincture. Elixir of Iron, Cinchona and Phos- phorus. See Elixir of Cinchona and its combi- nations. Elixir of Iron and Cinchonidine. PHARMACEUTICAL PREPARATIONS. 83 Elixir of Iron, Cinchonidine and Strychnine. See Elixir of Cinchonidine and its combinations. Elixir of Iron, Damiana, Nux Vom- ica and Phosphorus. Elixir of Iron, Damiana and Phos- phorus. See Elixir of Damiana and its combi- nations. Elixir of Iron Hypophosphite. Solution of iron hypophos- phite fl.dr. 13 Aromatic elixir, to make. . .fl.oz. 16 Mix, allow the mixture to stand a few days in a cool place, and filter, if nec- essary. Each fluidram contains 1 gr. of ferric hypophosphite. — N. F. Elixir of Iron and Hypophosphites. See Elixirs of the Hypophosphites. Elixir of Iron Malate, Cinchona and Gentian. See Elixir of Cinchona and its combi- nations. Elixir of Iron Lactate. Iron lactate, in crusts gr. 128 Potassium citrate gr. 384 Water fl.oz. 2 Aromatic elixir, to make, .fl.oz. 16 Dissolve the iron and potassium salts in the water by the aid of a gentle heat, add the elixir and filter. Each fluidram contains 1 gr. of iron lactate.— N. F. Elixir of Iron and Malt. See Elixir of Malt and Iron. Elixir of Iron, Malt and Beef. See Elixir of Beef and its combina- tions. Elixir of Iron and Pepsin. (Ferrat- ed Elixir of Pepsin.) See Elixir of Pepsin and Iron. Elixir of Iron, Pepsin and Quinine. Iron pyrophosphate, soluble, .gr. 256 Quinine hydrochlorid gr. 32 Distilled water, hot fl.oz. 1 Elixir of pepsin, to make, .fl.oz. 16 Dissolve the iron salt in the water, add the elixir and the quinine salt, agi- 6 tate occasionally until dissolved, and filter. Each fluidram contains 2 gr. of iron pyrophosphate, J4 § r - of quinine hydro- chlorid, and nearly 1 gr. of pepsin. Elixir of Iron Peptonate. I. Howard's formula : Peptone gr. 365 Solution of dialyzed iron.. fl.oz. zV\ Solution of soda fl.dr. 2}/i Alcohol fl.dr. 13 Aromatic elixir fl.dr. 5 Distilled water, to make. . . .fl.oz. 16 Dissolve the peptone in 32 fluidounces of distilled water, and add to the iron solution previously diluted with 32 fluid- ounces of distilled water. Then add enough of a dilute solution of soda to exactly neutralize the mixture. This is shown by the character of the precipi- tate which at the end of the reaction collects in large flakes and separates rapidly from the clear liquid. Wash the precipitate by decantation several times with water and drain on muslin or on a filter. Transfer the precipitate to a capsule, add the solution of soda diluted with 10 fluidrams of distilled water, stirring immediately and continu- ously until dissolved, then add 3 fluid- ounces of water, the elixir and alcohol, and lastly enough distilled water to make 16 fluidounces. Care must be taken throughout the manipulations to avoid loss and so weak- en the preparation. The solution contains 0.7 per cent, of iron, corresponding to 1 p. c. of ferric oxide. II. Pepsin, pure , gr. 4 Dried egg albumen gr. 30 Simple syrup fl.dr. 4 Solution of dialyzed iron or iron oxychlorid .fl.dr. I2j4 Aromatic elixir fl.dr. \2 l / 2 Distilled water, to make. .. .fl.oz. 16 Dissolve the albumen in z l A fluid- ounces of water, add the pepsin and di- gest for 4 hours at 50 deg. C. Mix the syrup and solution of iron with 9 fluid- ounces of the water, then add to the pepsin solution and heat to 90 deg. C. 84 STANDARD FORMULARY OF Cool, add the elixir and the remainder of the water. Set aside for 8 days and then decant the clear solution. If to the above be added 32 gr. of crystal manganese chlorid, previously dissolved in 1 fluidram of water, it will constitute Solution of Iron and Man- ganese Peptonate. III. The preparation under the title of Solution of Iron Peptonate may be dispensed as elixir of iron peptonate. Elixir of Iron Phosphate. Iron phosphate, soluble gr. 256 Water, distilled fl.oz. 1 Aromatic elixir, to make, .fl.oz. 16 Dissolve the iron phosphate in the water, mix this solution with the aro- matic elixir, and filter if necessary. Each fluidram contains 2 gr. of iron phosphate. — N. F. Elixir of Iron Phosphate, Cinchoni- dine and Strychnine. Iron phosphate, soluble gr. 256 Potassium citrate gr. 32 Cinchonidine sulfate gr. 64 Strychnine sulfate gr. 1% Alcohol fl.oz. 1 Distilled water, hot fl.dr. 6 Aromatic elixir, to make. . .fl.oz. 16 Dissolve the iron phosphate and potas- sium citrate in the water, using gentle heat, if necessary. To 12 fluidounces of aromatic elixir, contained in a bottle, add the alcohol, and afterwards the al- kaloidal salts, and agitate until the latter are dissolved, or nearly so. Then mix the two solutions, and, having shaken the mixture, add the remainder of the aromatic elixir. Finally, filter. This elixir should preferably not be dispensed in a mixture with water, as the latter may cause separation of some of its constituents. Each fluidram contains 2 gr. of iron phosphate, l / 2 gr. of cinchonidine sulfate, and 1/100 gr. of strychnine sulfate. — N. F. 1st edition. Elixir of Iron Phosphate and Gen- tian. See Elixir of Gentian and Iron Phos- phate. Elixir of Iron Phosphate, Quinine and Strychnine. I. Iron phosphate, soluble gr. 128 Quinine (alkaloid) gr. 64 Strychnine (alkaloid) gr. 2 Alcohol fl.oz. 2 Distilled water, warm fl.dr. 6 Aromatic elixir, to make. ..fl.oz. 16 Dissolve the alkaloids in the alcohol and add 12 fluidounces of aromatic elix- ir, then dissolve the iron phosphate in the water, and add to the previous mix- ture. Finally, add the remainder of the aromatic elixir, and filter. Each fluidram contains 1 gr. of iron phosphate, Yz gr. of quinine, and 1/64 gr. of strychnine. — N. F. (ist edition). If the iron phosphate is acid, its solu- tion should be very carefully neutralized with ammonia water. This preparation has been discarded by the present N. F. in favor of the elixir of iron pyrophosphate, quinine and strychnine. II. Hausmann's formula: Strychnine (alkaloid) gr. 1% Quinine sulfate gr. 64 Citric acid gr. 5 Iron phosphate, soluble gr. 256 Alcohol fl.oz. 3 Simple syrup fl.oz. 6 Distilled water, warm fl.oz. 4 Orange flower water fl.oz. 3 Sodium bicarbonate sufficient Triturate the strychnine and quinine sulfate with the acid until well mixed, and rub this mixture with the alcohol gradually added. Heat the syrup to about 65 deg. C, add to it the alcoholic liquid, and stir until clear. Dissolve the iron salt in the water, add the crange flower water, mix this with the prece- ding liquid, and allow to cool. Then add sodium bicarbonate in very small amounts, stirring thoroughly after each addition, until the elixir remains but slightly acid. xMlow to stand for a few hours, then filter through white filter paper. Any excess of soda must be avoided. PHARMACEUTICAL PREPARATIONS. 85 III. Steven's formula : Strychnine sulfate gr. i T A Quinine hydrochloric! gr. 128 Iron phosphate, soluble gr. 256 Potassium citrate gr. 32 Alcohol fl.oz. i l / 2 Distilled water, hot fl.oz. 1 Glycerin fl.dr. 18 Aromatic elixir, to make. . .fl.oz. 16 Dissolve the quinine salt in 10 fluid- ounces of elixir, mixed with the alcohol, by agitation, and mix this solution with the strychnine sulfate previously dis- solved in 2 fluidrams of the water. Dissolve the iron phosphate in 6 fluid- drams of the water, add 2 fluidounces of glycerin and mix this solution with the preceding liquid. Now to this mix- ture add the potassium citrate dissolved in i l / 2 fluidounces of aromatic elixir mixed with 2 fluidrams of glycerin. Al- low the whole to stand for several hours, then filter. IV. Edel's formula: Iron phosphate, soluble. ... ..gr. 256 Quinine sulfate gr. 128 Strychnine sulfate gr. i J A Alcohol fl.oz. 2 Glycerin fl.oz. 2 Simple syrup fl.oz. 2 Distilled water, warm fl.oz. 1 Aromatic elixir, to make. . .fl.oz. 16 Dissolve the strychnine salt in the al- cohol, and add the quinine; mix the glycerin and syrup, and heat, and when warm add to the alkaloidal solution; continue heating carefully, until the qui- nine is dissolved, and add enough elixir to make IS fluidounces. Dissolve the iron salt in the water, add this to previous liquid, let stand 3 or 4 hours, and filter. V. Remington's formula: Iron phosphate, soluble gr. 256 Quinine sulfate . .-. gr. 128 Strychnine sulfate gr. i J /i Alcohol fl.oz. 1 Simple syrup fl.oz. 8 Aromatic elixir, to make. . .fl.oz. 16 Dissolve the iron phosphate in the syr- up by the aid of heat, and raise the temperature to near the boiling point. Dissolve the alkaloidal salts in 6 fluid- ounces of aromatic elixir, contained in a flask, by the aid of heat, and while still hot add this solution all at once to the iron solution, shaking immediately. Al- low to stand 24 hours, then filter. VI. See also Elixir of Iron, Quinine and Strychnine Phosphates, Elixir of Iron Pyrophosphate, Quinine and Strychnine, and Elixir of Iron, Quinine^ and Strychnine. Elixir of Iron, Phosphorus, Quinine and Strychnine. See Elixir of Phosphorus, Compound. Elixir of Iron "Protoxid." Solution of iron "protoxid". fl.oz. 2 Simple elixir fl.oz. 14 Elixir of Iron "Protoxid" and Cin- chona. See Elixir of Cinchona and its combi- nations. Elixir of Iron Pyrophosphate. Iron pyrophosphate, solublc.gr. 256 Distilled water, warm fl.oz. I Aromatic elixir, to make. ..fl.oz. 16 Dissolve the iron pyrophosphate in the water, add the elixir, and filter, if nec- essary. ' Each fluidram contains 2 gr. of iron pyrophosphate. — N. F. Elixir of Iron Pyrophosphate and Ammonium Valerianate. Elixir of Iron Pyrophosphate, Am- monium Valerianate and Cin- chonidine. Elixir of Iron Pyrophosphate, Am- monium Valerianate, Cinchoni- dine and Quinine. Elixir of Iron Pyrophosphate, Am- monium Valerianate, Cinchoni- dine, Quinine and Strychnine. Elixir of Iron Pyrophosphate, Am- monium Valerianate, Cinchoni- dine and Strychnine. Elixir of Iron Pyrophosphate, Am- monium Valerianate and Qui- nine. Elixir of Iron Pyrophosphate, Am- monium Valerianate, Quinine and Strychnine. See Elixir of Ammonium Valerianate and its combinations. Elixir of Iron Pyrophosphate and Gentian. See Elixir of Gentian and its combina- tions. STANDARD FORMULARY OF Elixir of Iron Pyrophosphate and Quinine. This may be prepared like elixir of iron pyrophosphate, quinine and strych- nine, the strychnine to be omitted, of course. Elixir Iron Pyrophosphate, Quinine and Strychnine. I. Iron pyrophosphate, soluble, .gr. 256 Quinine sulfate gr. 64 Strvchnine (alkaloid) gr. 1 Citric acid gr. 5 Alcohol fl.oz. 4 Oil of orange (about 8 drops) m. 5 Simple syrup fl.oz. 6 Ammonia water, Distilled water, to make. . .fl.oz. 16 Triturate the quinine, strychnine and acid together until minutely divided, then add the alcohol and oil. Warm the syrup slightly (to about 65 deg. C.) and add to it the turbid alcoholic mixture which upon stirring should become clear. To this add the iron salt previously dis- solved in s l / 2 fluidounces of distilled wa- ter and then ammonia water, drop by drop, until the liquid is perfectly neutral to test paper. Finally add enough dis- tilled water to make 16 fluidounces, and filter.— N. F. Each fluidram contains 1/128 gr. of strychnine, Yz gr. of quinine sulfate and 2 gr. of iron pyrophosphate. II. Thompson's formula : Strychnine (alkaloid) gr. 1% Quinine (alkaloid) gr. 64 Iron pyrophosphate gr. 128 Alcohol fl.oz. 2 Distilled water, warm fl.oz. 3 Simple syrup fl.oz. 3 Aromatic elixir fl.oz. 8 Dissolve the strychnine and quinine in the alcohol, also the iron salt in the water, mix the two solutions, add the syrup and then the elixir, and filter, if necessary. III. Hausmann's formula: Strychnine (alkaloid) gr. \% Quinine sulfate gr. 64 Citric acid gr. 5 Iron pyrophosphate, solublc.gr. 256 Alcohol fl.oz. 3 Simple syrup fl.oz. 6 Distilled water, warm fl.oz. 4 Orange flower water fl.oz. 3 Sodium bicarbonate sufficient .Triturate together the alkaloids and the acid until thoroughly mixed; rub this with the alcohol gradually added. Heat the syrup to about 65 deg. C, add it to the alcoholic mixture, and stir until clear. Dissolve the iron salt in the wa- ter, and add the orange flower water ; mix the two solutions, and when cold, add carefully sodium bicarbonate in small portions until the elixir remains but slightly acid. Allow to stand for a few hours, then filter through white filter paper. Excess of soda must be carefully avoided. IV. Bechmann's formula: Quinine sulfate gr. 120 Strychnine sulfate gr. 2 Iron pyrophosphate gr. 240 Sodium or ammonium citrate gr. 60 Alcohol fl.oz. 2 Water fl.oz. 1 Glycerin fl.oz. 3 Simple elixir, to make fl.oz. 16 Put the quinine and strychnine in a flask, pour on the alcohol and 5 fluid- ounces of simple elixir, then place the flask in hot water, shaking occasionally until dissolved. Dissolve the iron in the water without heat, then add the sodium (or ammonium) citrate and the glycerin. Pour this solution into the previous so- lution and shake well. When cold add enough simple elixir to bring the quan- tity up to 16 fluidounces. Elixir of Iron Pyrophosphate and Strychnine. Iron pyrophosphate gr. 256 Strychnine sulfate gr. 1% Distilled water, hot fl.oz. 2 Simple elixir, to make fl.oz. 16 Dissolve the iron salt and strychnine sulfate in the hot water, add the elixir, and filter. Each fluidram contains 2 gr. of iron pyrophosphate and 1/100 gr. of strych- nine sulfate. PHARMACEUTICAL PREPARATIONS. 87 Elixir of Iron, Quinine and Arsenic. Tincture of iron citrochlo- rid fl.dr. 8H Quinine hydrochlorid gr. 64 Solution of arsenous acid. . . .m. 400 Simple elixir, to make fl.oz. 16 Dissolve the quinine salt in about 12 fluidounces of elixir, by agitation, add the acid solution, the tincture and the remainder of the elixir, and filter. Each fluidram contains 4 m. of tinc- ture of iron citrochlorid, Vz gr. of qui- nine hydrochlorid, and 1/32 gr. of ar- senous acid. Elixir of Iron and Quinine Citrate. (Elixir of Iron and Quinine.) Citrate of iron and quinine, .gr. 256 Water, warm fl.oz. 1 Aromatic elixir, to make. . .fl.oz. 16 Dissolve the citrate in the water, add the elixir, and filter. Each fluidram contains 2 gr. of iron and quinine citrate. Or prepare like elixir of iron, quinine and strychnine, which see, but omitting the strychnine. Elixir of Iron and Quinine Hypo- phosphites. Elixir of Iron, Quinine and Strych- nine Hypophosphites. See the Elixirs of Hypophosphites for these. Elixir of Iron and Quinine Hypo- phosphites. See Elixir Hypophosphites of Iron and Quinine. Elixir of Iron, Quinine and Strych- nine. Whenever elixir of iron, quinine and strychnine is asked for, the elixir of iron, quinine and strychnine phosphates of the U. S. P. or the preparation the formula for which is given below may be dispensed. Tincture of citrochlorid of iron fl.oz. 2 Quinine hydrochlorid gr. 64 Strychnine sulfate gr. 1*4 Comp. spirit orange fl.dr. \y 2 Alcohol fl.oz. 4 Purified talc dr. 3 Distilled water, to make fl.oz. 16 Dissolve the quinine salt in the alco- hol, add the compound spirit of orange, then the strychnine sulphate dissolved in \y 2 fluid drams water, the glycerin, the iron tincture and sufficient distilled water to make the product measure 16 fluid ounces. Add the purified talc and filter, returning the first portions to the fil- trate until it runs clear. Preserve in dark bottles.— N. F. Elixir of Iron, Quinine, Strychnine and Arsenic. See Elixir of Iron and Arsenic, Bitter. Elixir of Iron, Quinine and Strych- nine" Phosphates. (Elixir of Three or Triple Phosphates.) Nearly all of the preparations dis- pensed under this name contain the iron as phosphate or pyrophosphate, and the quinine and strychnine in some other form than as phosphate. If it be desired to dispense such a preparation as "elixir of three phosphates," then any of the preparations made according to formu- las given in this formulary under elixir o£ iron phosphate, or pyrophosphate, quinine and strychnine may be dis- pensed. The following formulas do actually contain the three bases in the form of phosphates. I. Iron phosphate, soluble gr. 128 Quinine (alkaloid) gr. 64 Strychnine (alkaloid) gr. 2 Phosphoric acid, U. S. P. or 85 per cent m. 15 Or phosphoric acid, 50 p. c. .m. 25 Acetic acid, 36 per cent gr. 225 Ammonium carbonate gr. 71 Alcohol fl.oz. 1 Ammonia water, distilled wa- ter, aromatic elixir, each, to make fl.oz. 16 Dissolve the quinine and strychnine in the alcohol, then add the phosphoric acid and 6 fluidounces of aromatic elixir. Add the ammonium carbonate to the acetic acid contained in a beaker or graduate, and when solution is com- plete, neutralize with ammonia water 88 STANDARD FORMULARY OF and add enough distilled water to bring the volume up to 6 fluidrams. Mix the ammonium acetate solution with the solution of quinine and strychnine phos- phates, and add enough aromatic elixir to make the liquid measure 14 fluid- ounces. Dissolve the iron salt in 4 fluidrams of distilled water by the aid of a gentle heat, and if the solution be acid to litmus paper, neutralize it ex- actly with ammonia water, add enough aromatic elixir to make 2 fluidounces, add this to the preceding liquid, and fil- ter the whole. This preparation conforms in strength to that claimed for the majority of the elixirs of the market, containing in each fluidrarn 1 gr. of iron phosphate, and ^2 gr. of quinine and 1/64 gr. of strych- nine, all in the form of the phosphates. If an elixir of twice the strength be desired, it can readily be made by doubling the quantities of all the ingre- dients, except the aromatic elixir. With some samples of iron phosphate, a slightly increased quantity of the am- monium acetate solution may be neces- sary, possibly owing to loss of water by evaporation and a consequent relative in- crease of the proportion of ammonia water. II. Patch's formula: Solution of iron chlorid, U. S. P fl.dr. 71/2 Quinine (alkaloid) gr. no Strychnine (alkaloid) gr. 1 Phosphoric acid, U. S. P. (85 per cent.) fl.dr. 2^ Distilled water fl.dr. 2 Alcohol fl.oz. 1 Simple elixir fl.oz. 10 Simple syrup, to make fl.oz. 16 Mix the iron solution, phosphoric acid and water, and in this mixture dissolve the alkaloids; to this solution add the syrup, and then elixir and alcohol pre- viously mixed. Some manufacturers place upon the market a so-called "permanent elixir of three phosphates," which contains the iron as citrochlorid ; a preparation of this character would be well represented by the elixir of iron, quinine and strych- nine. Elixir of Iron, Quinine and Zinc Valerianates. See Elixirs of Valerianates of differ- ent bases. Elixir of Iron Salicylate. Iron salicylate gr. 640 Distilled water, hot fl.oz. 2^ Glycerin fl.oz. 2 Y /\ Simple elixir, to make fl.oz. 16 Dissolve the iron salt in the hot water and glycerin, add the elixir, allow to stand for a few days and filter. Each fluidrarn contains 5 gr. of iron salicylate. Elixir of Iron Salicylate, Compound. Iron salicylate gr. 640 Distilled water, hot fl.oz. 2^4 Glycerin fl.oz. 2^4 Fluid extract of colchicum root fl.dr. 9 Deodorized tincture of opi- um fl.dr. 4I/2 Simple elixir, to make fl.oz. 16 Dissolve the iron salt in the hot water and glycerin, add the other ingredients, allow to stand a few days, and filter. Each fluidrarn contains 5 gr. of iron salicylate and represents about 4^ gr. of colchicum root and 2 m. of deodor- ized tincture of opium. Elixir of Iron Valerianate. Iron valerianate gr. 128 Alcohol fl.oz. 1 Simple elixir fl.oz. 15 Dissolve the iron salt in the alcohol, add the elixir, and filter. Each fluidrarn contains 1 gr. of iron valerianate. Elixir of Iron and Wild Cherry. (Ferrated Elixir of Wild Cherry.) Iron pyrophosphate gr. 128 Distilled water, hot fl.dr. 4 Fluid extract of wild cherry fl.oz. 2 Alcohol fl.oz. 2 Simple elixir, to make fl.oz. 16 Mix the alcohol and fluid extract, add the elixir, and then iron salt previously dissolved in the water, and filter through purified talcum. Each fluidrarn contains 1 gr. of iron PHARMACEUTICAL PREPARATIONS. 89 pyrophosphate, and represents 7^2 gr. of wild cherry. Elixir of Jaborandi. (Elixir of Pilo- carpus.) Fluid extract of jaborandi. .fl.oz. 1 Syrup of coffee fl.oz. 3 Tincture of vanilla fl.dr. 4 Compound elixir of taraxa- cum fl.oz. 11^ Mix, allow the mixture to stand dur- ing 4 days, if convenient, and filter. Each fluidram represents zVa gr. of jaborandi. Elixir of Juniper, Buchu and Potas- sium Acetate. Elixir of Juniper, Buchu, Potassium Acetate and Uva Ursi. See Elixir of Buchu and its combina- tions. Elixir of Juniper and Potassium Acetate. See Elixir of Potassium Acetate and Juniper. Elixir of Kola. Fluid extract of kola fl.oz. 2 Ammoniated glycyrrhizin gr. 60 Saccharin gr. 60 Oil of orange drops 5 Water fl.oz. 7 Alcohol fl.oz. 2>V2 Simple syrup .fl.oz. 3>4 Simple elixir, to make. .... .fl.oz. 16 Dissolve the ammoniated glycyrrhizin in the water and in this dissolve the sac- charin; add the syrup and alcohol, fol- lowed by the fluid extract of kola, to which has been added the oil of orange ; set aside for 5 or 6 hours, agitating oc- casionally; filter, and add the simple elixir. Or instead of the glycyrrhizin, J / 2 to 1' fluidounce of glycerite of licorice may be used. Each fluidram represents 7Y 2 gr. of kola. Elixir of Lactophosphate of Calcium, Cinchona and Iron. Elixir of Lactophosphate of Calcium. See Elixir of Calcium Lactophosphate and its combinations, Elixir of Licorice, Aqueous. Fluid extract of licorice. .. .fl.oz. 2Y 2 Compound spirit of carda- mom fi.dr. \y A Stronger oranger flower water fl.oz. 2>y 2 Glycerin fl.oz. 2 l / 2 Syrup fl.oz. 2y 2 Distilled water, to make fl.oz. 16 Mix and filter. — N. F. II. Extract of licorice, purified.. gr. 480 Ammonia water sufficient Aromatic elexir, to make, .fl.oz. 16 Triturate the extract with 12 fluid- ounces of elixir, to 10 fluidounces of this add ammonia water in slight ex- cess, add the reserved portion, then the remainder of the elixir, and filter if nec- essary. — N. F., 1st edition. This preparation is superior to No. I. A more superior preparation than either of the above can be made by mix- ing 1 fluidounce of glycerite of licorice with 15 fluidounces of elixir, and filter- ing. Elixir of glycyrrhizin, which see, is an acceptable substitute for this prepara- tion. III. Purified extract of licorice, .av.oz. 3^ Anisated solution of ammo- nia fl.oz. 3^4 Fennel water fl.oz. g x / 2 Dissolve the extract in the water and add the solution. — Germ. Pharm. The mixture is turbid and must be shaken before use. A more acceptable preparation and one more readily made may be obtained by mixing 6 l / 2 fluidounces of glycerite of licorice, 5 of fennel water and 3*4 of anisated solution of ammonia. This last preparation is best known by the names Elixir e Succo Lequiritise, Elixir Pectorale, Pectoral Elixir, Liquor Pectoralis, Brust Tropfen, Brust Elixir, and Bryst (or Brost) Draaber. Elixir of Licorice with Ammonium Chloride, Compound. See Elixir of Ammonium Chlorid. etc. 90 STANDARD FORMULARY OF Elixir of Licorice, Aromatic. (Com- pound Elixir of Licorice — "Qui- nine Elixir.") This elixir is employed for disguising the taste of bitter medicines, particularly quinine. No acid should be used be- cause it dissolves the quinine and makes its bitter taste more perceptible, and at the same time liberates the glycyrrhizin from its combination with ammonia and renders it insoluble, and therefore value- less for the purpose of disguising or modifying taste. I. Fluid extract of licorice. . .fl.oz. 2 Oil of clove m. 6 (about io drops.) Oil of cinnamon (Ceylon) .. .m. 6 (about io drops.) Oil of nutmeg m. 4 (about 6 drops.) Oil of fennel m. 12 (about 20 drops.) Purified talc gr. 120 Aromatic elixir fl.oz. 14 Triturate the oils with the talc and gradually add the fluid extract and elixir. Shake occasionally during an hour, set the mixture aside for a day or two if convenient, then filter. — N. F. A better preparation will be obtained if 1 fluidounce of glycerite of licorice be substituted for the fluid extract. II. Licorice root, coarse powder av.oz. 2 Wild cherry, coarse powder av.oz. 1 Red rose petals, coarse pow- der av.oz. Yi Orange peel, fresh, cut small av.oz. Y2 Alcohol fl.oz. 3 Glycerin fl.oz. 3 Water, to make fl.oz. 16 Mix the drugs, moisten them with 4 fluidounces of water and set in a warm place for 12 hours ; then, having mixed the alcohol and glycerin with 6 fluid- ounces of water, pack the drugs in a percolator and pour the mixture upon them; set aside for 12 hours, then begin to percolate, adding water to the drugs until 16 fluidounces of percolate have been obtained. III. Select licorice root, cut and slightly bruised av.oz. 2*4 Ammonia water fl.dr. 4 Glycerin fl.oz. 1 Water fl.oz. 16 Simple syrup fl.oz. 6 Alcohol fl.oz. 4 Spirit of orange fl.dr. 3 Oil of cinnamon (Ceylon) .drops 2 Macerate the drug with the glycerin, water and ammonia water for 24 hours, then strain, boil for 10 minutes, filter, evaporate the filtrate to 6 fluidounces ; to this add the simple syrup and the spirit and oil, the latter two previously dissolved in the alcohol. IV. Licorice root av.oz. 2 Anise gr. 40 Caraway gr. 40 Cinnamon gr. 40 Clove gr. 20 Nutmeg, powder gr. 10 Spirit of orange fl.dr. 4 Tincture of vanilla ...fl.dr. 2 Sugar av.oz. 8 Diluted alcohol sufficient Mix the drugs, reduce them to coarse powder, and extract them in the usual way, using diluted alcohol as the men- struum until 11 fluidounces of percolate are obtained. In the latter dissolve the sugar by agitation, strain, and add the tincture and spirit. V. See Elixir of Glycyrrhizin, Aromatic, which may be used as an aromatic elixir of licorice. Elixir of Licorice, Compound. Glycerite of licorice fl.oz. I Wine of antimony fl.oz. I Paregoric fl.oz. 2 Spirit of nitrous ether fl.dr. 4 Aromatic elexir, to make. . .fl.oz. 16 The above replaces "brown mixture" in the form of an elixir. The name compound elixir of licorice is also applied to aromatic elixir of licorice, but should be applied to the above only. PHARMACEUTICAL PREPARATIONS. 91 Elixir of Life. (Elixir Vitee.) Syrup of iron iodid. fl.dr. 2 Syrup of hypophosphites. .. .fl.dr. 2 Glycerin fl.dr. 2 Water, to make fl.oz. 3 —New York Hospitals . Elixir of Lithium Bromid. Lithium bromid gr. 640 Syrup fl.oz. 3V 2 Distilled water fl.oz. 8 Aromatic elixir, q. s fl.oz. 16 Dissolve the lithium bromide in the distilled water, add the syrup and suffi- cient elixir to make 16 fl. ozs. ium bromid. — N. F. Elixir of Lithium Citrate. Lithium citrate gr. 640 Aromatic elixir, to make. . .fl.oz. 16 Dissolve by agitation, and filter. Each fluidram contains 5 gr. of lithium citrate.— N. F. Elixir of Lithium Salicylate. Lithium salicylate gr. 640 Aromatic elixir, to make, .fl.oz. 16 Dissolve by agitation, and filter. Each fluidram contains 5 gr. of lithium salicylate. — N. F. Elixir of Long Life. (Elixir ad Longam Vitam — Elixir of Life — Compound Tincture of Aloes — "Swedish Bitters" — Kronessens — Wunder Kronessens — Hjerne's Testament Drops — Elixir Sacrum — Lebens Essenz — Jenaer Trop- fen.) Aloes av.oz. y 2 Rhubarb gr. 35 Gentian gr. 35 Zedoary gr. 35 Spanish saffron gr. 35 Water fl.oz. tf/2 Alcohol fl.oz. 13 Mix the drugs in coarse powder with the two liquids, macerate for 3 days, ag- itating frequently; express and filter. — Germ. Pharm. Sometimes 35 gr. of agaric is added to the other drugs and the menstruum em- ployed is diluted alcohol. The following is a simple formula which may be used for the preparation of this ancient and complicated remedy : Tincture of aloes fl.oz. 8 Tincture of rhubarb fl.oz. 2 Compound tincture of gen- tian fl.oz. 1 Water fl.oz. 1 Alcohol ... fl.oz. 4 Elixir of Lupulin. Fluid extract of lupulin fl.oz. 1 Magnesium carbonate av.oz. 1 Simple elixir, to make fl.oz. 16 Triturate the fluid extract with the magnesium carbonate, add the elixir, transfer to a bottle, set aside for several hours, and filter. The above is of the strength usually furnished by manufacturers; Diehl's formula, which is largely used, directs the use of 2 fluidounces of the fluid ex- tract to the pint of finished elixir. Elixir of Lupulin and Sodium Bro- mid. Fluid extract of lupulin. . . .fl.dr. io^ Purified talcum gr. 120 Sodium bromid gr. 640 Aromatic elixir of licorice, to make fl.oz. 16 Triturate the fluid extract with the talcum, add some of the elixir, transfer to a bottle, add the sodium salt and the remainder of the elixir, dissolve by agi- tation, and filter after several hours. Each fluidram represents 5 gr. of lupu- lin and contains 5 gr. of sodium bromid. Elixir of Malt, Beef and Iron. See Elixir of Beef and its combina- tions. Elixir of Malt with Calcium and Sod- ium Hypophosphites. See Elixir of Calcium Hypophosphite and its combinations. Elixir of Malt and Iron. Extract of malt fl.oz. 4 Iron phosphate, soluble gr. 128 Water, warm fl.dr. 4 Aromatic elixir, to make. ..fl.oz. 16 Dissolve the iron phosphate in the water by the aid of heat, mix the solu- tion with the extract of malt, and add the elixir. Set the mixture aside for 24 hours, and filter. Each fluidram represents 1 gr. of iron phosphate and 15 m. of extract of malt. Extract of malt, most suitable for this 9? STANDARD FORMULARY OF preparation, should have about the con- sistence of Peru balsam at a tempera- ture of 15 deg. C. Elixir of Manaca and Salicylates. Fluid extract of manaca. . .fl.oz. 2 l / 2 Sodium salicylate av.oz. I$4 Potassium salicylate gr. 384 Lithium salicylate gr. 96 Simple elixir, to make fl.oz. 16 Dissolve the salicylates in some of the elixir, add the fluid extract and the re- mainder of the elixir, allow to stand for a few hours, and filter through talcum. Each fluidram contains 6 gr. of so- dium salicylate, 3 gr. of potassium sali- cylate, and 24 gr. of lithium salicylate, and represents 10 gr. of manaca. Elixir of Matico. Fluid extract of matico fl.oz. 3 Alcohol fl.oz. 1 Aromatic elixir fl.oz. 12 Mix, and filter through purified talcum if necessary. Elixir of Matico, Compound. Fluid extract of matico fl.oz Fluid extract of buchu fl.oz Fluid extract of cubeb fl.oz Alcohol fl.oz Simple elixir fl.oz. 4 Compound elixir of taraxa- cum fl.oz. 4 Mix, set aside for 3 days, and filter through talcum. Each fluidram represents 11 gr. of matico and nearly 6 gr. each of buchu and cubeb. Elixir Mercury and Arsenic Iodids. See Elixir of Arsenic and its combi- nations. Elixir of Mercury, Arsenic and Iron Chlorids. See Elixirs of Chlorids for above. Elixir of Morphine Valerianate. Morphine valerianate gr. 16 Simple elixir fl.oz. 16 Dissolve by agitation, and filter. Each fluidram contains ]4> gr. of mor- phine valerianate. Elixir of Nitroglycerin, Compound. Spirit of nitroglycerin m. 128 Fluid extract of digitalis m. 64 Tincture of strophantus, .fl.dr. 4% Strychnine sulfate gr. 2^ 3 1/2 1/2 2 Distilled water fl.dr. 2 Aromatic elixir, to make. . .fl.oz. 16 Dissolve the strychnine sulfate in the water by the aid of heat, allow it to cool, and add the other ingredients. Each fluidram contains 1/100 m. of nitroglycerin, 1/50 gr. of strychnine sul- fate, Yi m. of tincture of digitalis, and 2 m. of tincture of strophanthus. Elixir of Nux Vomica, Bismuth and Pepsin. See Elixir of Bismuth and its combi- nations. Elixir of Nux Vomica, Damiana, Iron and Phosphorus. See Elixir of Damiana and its combi- nations. Elixir of Nux Vomica and Phospho- rus. Tincture of nux vomica m. 65 Elixir of phosphorus, to make fl.oz. 4 Mix them. This preparation should be freshly made, when wanted for use. — N. F. Each fluidram represents 2 m. of tinc- ture of nux vomica, and about 1/60 gr. of phosphorus. Elixir of Orange. Oil of orange m. 100 Alcohol fl.oz. 14 Water fl.oz. 22 Simple syrup fl.oz. 28 Purified "talcum av.oz. y 2 Mix the oil and alcohol, add the tal- cum, shake well, then add the other in- gredients in small portions at a time, agitating well after each addition, and filter.— U. S. P. 1880 modified. The oil used should be a perfectly fresh sweet oil of orange peel. Simple syrup is used in place of the sugar. and corresponding amount of the water in the U. S. P. 1880 formula. Elixir of Orange, Compound. (Elixir Aurantiorum Composition. — Compound Wine of Orange. — Vinum Amarum, Bitter Wine. — Elixir Stomachicum, Stomachic Elixir. — Elixir Viscerale Hoff- manni. — Hoffmann's Stomach Elixir. — Pomeranzen Elixir.) Bitter orange peel, cut gr. 1600 Cinnamon, bruised , ., gr. 320 PHARMACEUTICAL PREPARATIONS. 93 Potassium carbonate gr. 80 Extract of gentian gr. 160 Extract of wormwood gr. 160 Extract of bnckbean gr. 160 Extract of cascarilla gr. 160 Sherry wine fl.oz. 17J/2 Macerate the orange peel, cinnamon, and potassium carbonate with the sherry wine for 8 days, agitating occasionally ; express the liquid portion, in the latter dissolve the extracts, and filter. The National Formulary also recog- nizes what is identically the same prep- aration under the title of Compound Wine of Orange and which is intended to be used in place of the above ; in the latter no extracts are used, but the drugs themselves are mixed with the orange peel, cinnamon, and potassium carbonate, the whole being extracted by percola- tion. See Wine of Orange, Compound. The N. F. formula should receive pref- erence. Elixir of Pancreas. Take 1 pig pancreas, chop into pieces, and macerate in a cool place for 3 days in a mixture of — Water fl.oz. 32 Glycerin fl.oz. 6^2 Hydrochloric acid fl.dr. 5 Strain, add H fluidram of oil of or- ange and enough glycerin to make 48 fluidounces, and filter. The oil of orange and last portion of glycerin may be replaced by simple elixir. Elixir of pancreatin may be used in place of this preparation. Elixir of Pancreatin. Pancreatin, pure gr. 128 Sodium bicarbonate gr. 16 Water fl.oz. 2 Simple elixir, to make fl.oz. 16 Macerate the pancreatin in the water for 24 hours, add the sodium bicarbon- ate, triturate until dissolved, gradually add the elixir, and filter. Each fluidram represents 1 gr. of pan- creatin. The elixir of pancreas may be sub- stituted for the above, if deemed desir- able. Elixir of Pancreatin and Bismuth. See Elixir of Bismuth and its combi- tions. Elixir of Pancreatin, Bismuth and Pepsin. Citrate of bismuth and am- monium gr. 128 Pancreatin, pure gr. 64 Pepsin, pure gr. 64 Distilled water, hot fl.oz. 1 Ammonia water sufficient Glycerin .fl.oz. 2 Water fl.oz. 2 Tincture of cudbear fl.dr. 2 Simple elixir, to make fl.oz. 16 Triturate the bismuth salt with the water, allow the insoluble portion to sub- side, decant the clear portion, to the residue add ammonia water very gradu- ally, until solution occurs, carefully avoiding any excess, and mix this liquid with the decanten portion. Macerate the pepsin and pancreatin with the glycerin and water for 24 hours, agitating occasionally; add the tincture, the bismuth solution, and the" elixir, and filter through purified talcum. One fluidounce of glycerite of bis- muth and sodium tartrate may be used for the bismuth salt of the above and the water and ammonia water used to dissolve it. Each fluidram contains 1 gr. each of pepsin and of bismuth salt, and Yz gr. of pancreatin. Elixir of Pancreatin, Potassium and Rhubarb. See Elixir of Rhubarb and its combi- nations. Elixir of Papain. Papain gr. 256 Glycerin fl.oz. 2 Aromatic elixir fl.oz. 14 Mix, macerate for 7 days, agitating occasionally, and filter. Each fluidram contains 2 gr. of pa- pain. Elixir of Paraldehyde. (25 per cent.) Paraldehyde fl.oz. 4 Glycerin fl.oz. 2 Alcohol . ,-r fl.oz. 5 Tincture of cardamom fl.dr. 2 Oil of orange m. 15 94 STANDARD FORMULARY OF Oil of cinnamon m. 15 Compound tincture of cud- bear fl.dr. 2 Aromatic elixir, to make. .. .fl.oz. 16 Mix the ingredients in the order giv- en, and filter, if necessary. Each fluidram contains 15 m. of paral- dehyde. Elixir of paraldehyde varies in strength from 10 to 25 per cent., as pre- scribed in different localities. The form- ula here given produces a 25 per cent, elixir, and from this the weaker prep- arations may readily be made by the ad- dition of aromatic elixir colored with compound tincture of cudbear in the proportion used in the above formula. To make a 20 per cent, elixir of paral- dehyde, for instance, 4 fluidounces of the 25 per cent, elixir are mixed with 1 fluidounce of colored aromatic elixir. To make 5 fluidounces of 15 per*cent. elixir, 3 fluidounces of the 25 per cent, elixir are required, and to make the same quantity of 10 per cent, elixir, 2 fluidounces of the above elixir are re- quired. Elixir of Pareira and Buchu. Elixir of Pareira and Buchu, Com- pound. See Elixir of Buchu and its combina- tions. Elixir of Pepsin. Glycerite of pepsin fl.oz. s l A Glycerin fl.dr. 13 Hydrochloric acid m. 30 Aromatic elixir, to make. . . .fl.oz. 16 Mix, allow to stand several days, if convenient, and filter if necessary. Each fluidram contains 1 gr. of pepsin. — X. F. Elixir of Pepsin and Bismuth. Elixir of Pepsin, Bismuth and Cin- chona. Elixir of Pepsin, Bismuth, Cinchona and Iron. Elixir of Pepsin, Bismuth, Cinchona, Iron and Strychnine. Elixir of Pepsin, Bismuth and Iron. Elixir of Pepsin, Bismuth, Iron and Quinine. Elixir of Pepsin, Bismuth and Nux Vomica. Elixir of Pepsin, Bismuth and Qui- Elixir of Pepsin, Bismuth, and Strychnine. Elixir of Pepsin, Bismuth and Wafer Ash. See Elixir of Bismuth and its combi- nations. Elixir of Pepsin and Cinchona. Elixir of Pepsin, Cinchona and Iron. Elixir of Pepsin, Cinchona and Strychnine. See Elixir of Cinchona and its combi- nations. Elixir of Pepsin, Compound. (Elixir of Lactated, or Lactinated, or Lacticated Pepsin. — Compound Digestive Elixir.) I. Pepsin, soluble scales (1:3000) -. gr. 75 Pancreatin, pure gr. 8 Diastase gr. 8 Lactic acid gr. 4 Hydrochloric acid m. 8 Glycerin fl.oz. 4 Water fl.oz. 2 Tincture of cudbear fl.dr. 2 Talcum, purified .gr. 120 Aromatic elixir, to make. ..fl.oz. 16 Mix the acids with the water and glycerin, and to this mixture add the pepsin, pancreatin, and diastase, and macerate until solution is apparently ef- fected ; then add the tincture and aro- matic elixir ; thoroughly incorporate the talcum, and filter. The best commercial variety of dias- tase, capable of converting the largest amount of starch into dextrin and glu- cose, should be used for this prepara- tion. It is now known that pepsin, pancrea- tin and diastase mutually destroy one another when present together in a liquid, in a period of from 3 to 6 weeks, and hence this and similar preparations should either be discontinued entirely or else made in only such quantities as will e quickly consumed. PHARMACEUTICAL PREPARATIONS. II. Pepsin, pure gr. 80 Pancreatin gr. 20 Diastase or ptyalin gr. 8 Cudbear, powder gr. 90 Diluted hydrochloric acid. . .fl.dr. 1 Lactic acid drops 5 Spirit of orange fl.dr. 2 Alcohol fl.oz. 5 Water fl.oz. 7 Simple syrup fl.oz. 4 Mix all the above except the syrup, macerate for 3 days, agitating frequent- ly ; filter, to the filtrate add the syrup, and then through the filter add, if nec- essary, enough of a mixture of alcohol and wate^ in the proportion of 5 to 7 by measure, to make the liquid measure 16 fluidounces. The first formula should be preferred, but the second more nearly conforms to many of the commercial preparations. Elixir of Pepsin and Iron. Tincture of iron citrochlo- rid fl.dr. 9^ Elixir of pepsin, to make. . .fl.oz. 16 Mix and filter, if necessary. Each fluidram represents about Yi gr. of iron (ferric) chlorid and nearly 1 gr. of pepsin. — N. F. Elixir of Pepsin, Iron and Quinine. See Elixirs of Iron and combinations. Elixir of Pepsin and Strychnine. Strychnine sulfate gr. i 1 /^ Distilled water fl.dr. 4 Elixir of pepsin fl.oz. 15^2 Dissolve the alkaloidal salt in the wa- ter by the aid of heat, and add the elixir. Each fluidram contains 1/100 gr. of strychnine sulfate and nearly 1 gr. of pepsin. Elixir of Pepsin and Wafer Ash. (Elixir Pepsin and Ptelea.) Pepsin, pure (1 13000) gr. 128 Fluid extract of wafer ash. fl.oz. 2 Purified talcum av.oz. Y\ Simple elixir fl.oz. 14 Add the pepsin to the simple elixir, agitate until dissolved, add the remain- ing ingredients, set aside for 24 hours, and filter. Each fluidram contains 1 gr. of pepsin and represents 7^2 gr. of wafer ash. Elixir of Phorphorus. I. Spirit of phosphorus. .. fl.oz. 3^ Oil of anise m. 15 Glycerin fl.oz. 9 Aromatic elixir, to make. . . .fl.oz. 16 To the spirit, contained in a gradu- ated bottle, add the oil and glycerin, and mix them by repeatedly inverting the bottle until they form a clear liquid. Then add the elixir, in several portions, gently agitating after each addition, un- til a transparent liquid is obtained. Keep the product in dark amber-col- ored, well-stoppered bottles, in a cool and dark place. — U. S. P. 1890 and N. F. Each fluidram contains about 1/60 gr. of phosphorus. II. Compound tincture of phos- phorus fl.oz. 1 Glycerin fl.oz. 4 Add the tincture to the glycerin and shake well. This elixir should be freshly prepared and should be preserved from the light in full bottles. — Brit. Form. Each fluidram contains 1/30 gr. of phosphorus. Elixir of Phosphorus, Cinchona and Iron. See Elixir of Cinchona and its com- binations. Elixir of Phosphorus and Coca. See Elixir of Coca and its combina- tions. Elixir of Phosphorus, Compound. (Elixir of Phosphorus, Iron, Qui- nine and Strychnine.) Strychnine sulfate gr. \ x /\ Quinine sulfate gr. 64 Iron phosphate gr. 128 Tincture of cudbear fl.dr. 2 Distilled water, warm fl.oz. 1 Alcohol fl.oz. 1 Elixir of phosphorus fl.oz. 8 Simple elixir, to make fl.oz. 16 Dissolve the strychnine salt in 4 fluid- drams of the water, and the iron salt in the remainder of the water. Mix the alcohol and elixir of phos- phorus, add the two solutions already 96 STANDARD FORMULARY OF prepared, then the quinine salt and the simple elixir, agitate until dissolved, and filter in a well-covered funnel. Each fluidram contains i/ioo gr. of strychnine sulfate, i gr. of iron phos- phate, Yi gr. of quinine sulfate, and i/ioo gr. of phosphorus. Elixir of Phosphorus and Damiana. Elixir of Phosphorus, Damiana and Iron. Elixir of Phosphorus, Damiana, Iron and Nux Vomica. Elixir of Phosphorus, Damiana and Nux Vomica. Elixir of Phosphorus, Damiana and Strychnine. See Elixir of Damiana and its combi- nations. Elixir of Phosphorus and Gentian. See Elixir of Gentian and its combi- nations. Elixir of Phosphorus and Nux Vom- ica. See Elixir of Nux Vomica and its combinations. Elixir of Phosphorus, Quinine and Strychnine. Elixir of phosphorus fl.oz. 8 Quinine hydrochlorid gr. 32 Strychnine sulfate gr. i}4 Distilled water, hot fl.dr. 4 Tincture of cudbear fl.dr. 2 Simple elixir, to make fl.oz. 16 Dissolve the quinine salt in 7 fluid- ounces of simple elixir, and the strych- nine salt in the water, mix the two so- lutions, then add the other ingredients, ■dissolve by agitation, and filter in a •well-covered funnel. Each fluidram contains 1/100 gr. of strychnine sulfate, ]/[ gr. of quinine hy- drochlorid, and i/ioo gr. of phosphorus. Elixir of Phosphorus and Strych- nine. Strychnine sulfate gr. 154 Distilled water fl.dr. 4 Elixir of phosphorus fl.oz. 8 Tincture of cudbear fl.dr. 2 Simple elixir, to make fl.oz. 16 Dissolve the quinine salt in the water and add the remaining ingredients. Each fluidram contains 1/100 gr. each of phosphorus and strychnine sulfate. Elixir of Potassium Acetate. Potassium acetate gr. 640 Aromatic elixir, to make. . .fl.oz. 16 Dissolve the potassium acetate in the elixir, and filter, if necessary. Each fluidram contains 5 gr. of po- tassium acetate. — N. F. Elixir of Potassium Acetate, Buchu and Juniper. Elixir of Potassium Acetate, Buchu, Juniper and Uva TJrsi. See Elixir of Buchu and its combina- tions. Elixir of Potassium Acetate and Juniper. Potassium acetate gr. 640 Fluid extract of juniper ber- ries fl.oz. 2 Purified talc gr. 120 Aromatic elixir, to make. ..fl.oz. 16 Triturate the fluid extract with the talc, add 12 fluidounces of aromatic elix- ir in which the potassium acetate has previously been dissolved ; then add enough aromatic elixir to make 16 fluid- ounces and shake occasionally. Allow to stand for a day or two if convenient, and filter.— N. F. Each fluidram represents 5 gr. of po- tassium acetate and 7^2 gr. of juniper berries. Elixir of Potassium Bromid. See the Elixirs of Bromids. Elixir of Potassium Iodid. See Elixir of Iodid of Potassium. Elixir of Potassium Iodid, Com- pound. See Elixir of Iodid of Potassium. Compound. Elixir Proprietatis. (Tincture Aloes Crocata.) Aloes, coarse powder av.oz. 1 Myrrh, coarse powder av.oz. 1 Spanish saffron av.oz. % Alcohol fl.oz. 16 Mix, macerate for 8 days, and filter. In the United States, the official tinc- ture of aloes and myrrh is frequently dispensed for the above preparation. For elixir proprietatis Paracelsi, see Elixir of Aloes, Acid. PHARMACEUTICAL PREPARATIONS. Elixir, Pulmonic. (Pectoral Elixir- Lung Tonic.) Pure extract of licorice gr. 300 Fluid extract of squill m. 128 Fluid extract of senega m. 128 Fluid extract of henbane leaves m. 128 Fluid extract of ipecac m. 64 Morphine sulfate gr. 8 Distilled water fl.dr. 4 Tincture of cacao fl.oz. 1 Elixir of cherries, to make. fl.oz. 16 Dissolve the morphine salt in the water, add the licorice extract, mix well, add the remaining ingredients, and filter. Ten fluidrams of glycerite of licorice may be substituted for the extract of licorice. Each fluidram contains 1/16 gr. of morphine sulfate. Elixir of Quinine and Ammonium Valerianate. Elixir of Quinine, Ammonium Vale- rianate and Cinchonidine. Elixir of Quinine, Ammonium Val- erianate, Cinchonidine and Iron. Elixir of Quinine, Ammonium Val- erianate, Cinchonidine, Iron and Strychnine. Elixir of Quinine, Ammonium Val- erianate, Cinchonidine and Strychnine. Elixir of Quinine, Ammonium and Strychnine Valerianates. See Elixir of Ammonium Valerianate and its combinations. Elixir of Quinine and Arsenic. Elixir of Quinine, Arsenic and Iron. See Elixir -of Arsenic and its com- binations. Elixir of Quinine and Bismuth. Elixir of Quinine, Bismuth, Iron and Pepsin. Elixir of Quinine, Bismuth and Pep- sin. See Elixir of Bismuth and its com- binations. Elixir of Quinine Bisulfate. Quinine bisulfate gr. 128 Simple elixir fl.oz. 16 Dissolve by agitation and filter, if necessary. Each fluidram contains 1 gr. of qui- nine bisulfate. Elixir of Quinine and Croton Chlo- ral. See Elixir of Croton Chloral Hydrate and its combinations. Elixir of Quinine, Iron and Bismuth. See Elixirs containing Bismuth. Elixir of Quinine and Iron Citrate. Elixir of Quinine, Iron and Pepsin. Elixir of Quinine, Iron and Strych- nine. Elixir of Quinine and Iron Hypo- phosphites. Elixir of Quinine, Iron and Strych- nine Hypophosphites. Elixir of Quinine, Iron Phosphate and Strychnine. Elixir of Quinine, Iron and Strych- nine Phosphates. Elixir of Quinine and Iron Pyro- phosphate. Elixir of Quinine, Iron Pyrophos- phate and Strychnine. See Elixir of Iron and its combina- tions. Elixir of Quinine, Iron, Phosphorus and Strychnine. See Elixir of Phosphorus, Compound. Elixir of Quinine, Iron and Zinc Valerianates. See Elixirs of the Valerianates. Elixir of Quinine and Phosphates, Compound. Quinine sulfate gr. 32 Iron phosphate, soluble gr. 128 Potassium citrate gr. 128 Syrup of calcium lactophos- phate fl.oz. 4 Water, warm fl.dr. 4 Aromatic elixir, to make. ..fl.oz. 16 Dissolve the quinine sulfate in 10 fluidounces of aromatic elixir, if neces- sary, with the aid of a gentle heat. Dis- solve the iron pohsphate and the potas- sium citrate in the water, and add the solution to that first prepared. Then add the syrup of calcium lactophosphate and lastly the remainder of the elixir ; filter, if necessary. Each fluidram contains x /\ gr. of qui- 98 STANDARD FORMULARY OF nine sulfate. I gr. of iron phosphate, and about 34 gr- of so-called calcium lactophosphate. The above is very similar to Elixir of Cinchona. Iron and Calcium Lacto- phosphate, which see. Elixir of Quinine, Phosphorus and Strychnine. See Elixir of Phosphorus and its com- binations. Elixir of Quinine and Strychnine. Quinine sulfate gr. 64 Strychnine sulfate gr. i l A Simple elixir fl.oz. 16 Dissolve the alkaloidal salts in the elixir by agitation, and filter. Each fluidram contains Yi gr. of qui- nine sulfate and 1/100 gr. of strychnine sulfate. Elixir of Quinine Valerianate. Quinine valerianate gr. 128 Tincture of cudbear fl.dr. 2 Simple elixir, to make fl.oz. 16 Triturate the quinine valerianate with a little of the elixir to a smooth paste. Add about 8 fluidounces more of elixir, triturate until dissolved, add the tinc- ture and the remainder of the elixir. Each fluidram contains 1 gr. of qui- nine valerianate. Elixir of Quinine and Strychnine Valerianates. Strychnine (alkaloid) gr. ^ \ x /\ Valerianic acid sufficient Quinine valerianate gr. 128 Tincture of cudbear fl.dr. 2 Simple elixir, to make fl.oz. 16 Triturate the strychnine and quinine valerianate with a little elixir to a smooth paste, add 4 fluidounces of elixir and just enough valerianic acid to dis- solve the alkaloids; then add the tincture and the remainder of the elixir, and fil- ter. Should the liquids, before filtra- tion, contain a slight excess of valerianic acid, which would betray itself by its odor, this should be cautiously neutral- ized by stirring with a glass rod repeat- edly dipped into very dilute ammonia water. Each fluidram contains 1 gr. of qui- nine valerianate and 1/100 gr. of strych- nine valerianate. Elixir of Quinine Valerianate and Strychnine. Quinine valerianate gr. 128 Strychnine sulfate gr. 1% Compound tincture of cud- bear fl.dr. 2 Distilled water min. 80 Aromatic elixir, to make. ..fl.oz. 16 Dissolve the strychnine sulphate in the distilled water, mix the solution with 13 fluid ounces aromatic elixir, and dis- solve the quinine valerianate in this mixture. Then add the remainder of the aromatic elixir, and filter, if neces- sary. — N. F. Each fluidram contains 1 gr. of qui- nine valerianate, and 1/100 gr. of strych- nine sulfate. Elixir of Rhubarb. I. Sweet tincture of rhubarb. . .fl.oz. 8 Alcohol fl.oz. 1 Glycerin fl.oz. 2 Simple syrup fl.oz. 2 Water fl.oz. 3 Mix and filter. Each fluidram represents about 3 gr. of rhubarb. II. Rhubarb, No. 12 powder, .av.oz. 4 Fennel, bruised . . . .av.oz. 1. .gr. 290 Glycerin fl.oz. 2^2 Sugar av.oz. 3% Alcohol, water, each, to make fl.oz. 16 Mix alcohol and water in the propor- tion of 1 volume of the former to 3 of the latter, moisten the mixed rhubarb and fennel with 12 fluidounces of this mixture, macerate for 48 hours, and ex- press. Break up the marc, add to it enough menstruum to make with the previous pressing 12 fluidounces of clear product. Express again after 24 hours' maceration. Unite the liquids, allow to stand for 2 days, and filter into the mixed glycerin and sugar. Dissolve the sugar by agitation without heat, and if necessary add enough of the same men- struum to make 16 fluidounces of prod- uct.— Brit. Form. PHARMACEUTICAL PREPARATIONS. 99 Elixir of Rhubarb, Aromatic. Aromatic fluid extract of rhubarb fl.oz. I Simple elixir fl.oz. 15 This is of the same strength as the aromatic syrup of rhubarb of the U. S. P. Elixir of Rhubarb and Magnesium Acetate. (Elixir of Rhubarb and Magnesia.) Magnesia, calcined gr. 150 Acetic acid, U. S. P. or 36% sufficient Fluid extract of rhubarb, .fl.oz. 2 Aromatic elixir, to make. . .fl.oz. 16 Dissolve the magnesia in 2^2 fluid- ounces of acetic acid, with the aid of a gentle heat, adding, if necessary, a little more acid, drop by drop, until the solu- tion is neutral to test-paper. Then add the fluid extract and the elixir, allow to stand a day or two if convenient, and filter. Each fluidram represents about 4 gr. of magnesium acetate and 7^ gr. of rhubarb. Elixir of Rhubarb, Magnesia and Senna. Magnesia, calcined gr. 144 Acetic acid sufficient Fluid extract of rhubarb, .fl.dr. &y 2 Fluid extract of senna fl.dr. 8^ Aromatic elixir, to make. . .fl.oz. 16 Dissolve the magnesia in 2 l /> fluid- ounces of acetic acid with the aid of a gentle heat, adding, if necessary, a little more acetic acid, drop by drop, until the solution is neutral to test-paper; then add the fluid extracts and elixir, and filter. Each fluidram contains 4 gr. of mag- nesium acetate and represents 4 gr. each of rhubarb and senna. Elixir of Rhubarb and Potassium, Compound. (Neutralizing Elix- ir.) Rhubarb gr. 240 Golden seal gr. 120 Cinnamon gr. 120 Potassium bicarbonate gr. 240 Spirit of peppermint fl.dr. 1 Simple syrup fl.oz. 2 Diluted alcohol, simple elixir, each sufficient 7 Reduce the three drugs to moderately coarse powder, extract them in the usual way by percolation with diluted alcohol until 6 fluidounces of percolate are ob- tained. In this percolate dissolve the potassium bicarbonate, add the spirit, syrup, and enough elixir to make 16 fluidounces of product, and filter. This preparation represents the well- known syrup of rhubarb and potassium in the elixir form. Elixir of Rhubarb and Potassium with Pancreatin. Rhubarb gr. 320 Golden seal gr. 160 Cinnamon gr. 160 Potassium bicarbonate gr. 320 Pancreatin , L . .gr. 32 Spirit of peppermint fl.dr. 1 Simple syrup fl.oz. 2 Diluted alcohol, simple elixir, each sufficient Moisten the rhubarb, golden seal and cinnamon (first reduced to a suitable powder), with diluted alcohol, and pack moderately in a percolator; allow to ma.cerate 48 hours and then percolate with diluted alcohol until 6 ounces have been obtained; in the percolate dissolve the potassium bicarbonate and add the pancreatin previously mixed with the syrup, and about 4 fluidounces of elixir ; mix thoroughly, add the spirit and enough elixir to make the whole meas- ure 16 fluidounces, and filter. This is similar to the preceding, con- taining only pancreatin in addition. Like the preceding also, it may be prepared with fluid extracts. Elixir of Rhubarb and Senna. Fluid extract of rhubarb. . . .fl.oz. 2 Fluid extract of senna fl.oz. 2 Tincture of cacao fl.oz. 2 Aromatic elixir fl.oz. 10 Mix and filter, if necessary. Each fluidram represents j l / 2 gr. each of senna and rhubarb. Elixir of Saccharin. (Elixir of Glu- side.) Saccharin gr. 384 Sodium bicarbonate gr. 192 Alcohol fl.oz. 2 Distilled water, to make. . .fl.oz. 16 100 STANDARD FORMULARY OF Rub the saccharin and sodium bicar- bonate in a mortar with 8 fluidounces of water gradually added ; when dis- solved, add the alcohol, filter, and wash the filter with the remainder of the water.— Brit. Form. Twenty minims contain I gr. of sac- charin. This preparation is intended as a sweetening agent in place of sugar or syrup. See also Solution of Saccharin. Elixir of Salicylic Acid. Salicylic acid gr. 640 Potassium citrate gr. 960 Glycerin fl.oz. 8 Aromatic elixir, to make. ..fl.oz. 16 Dissolve the potassium citrate in the glycerin with the aid of a gentle heat, add the acid, and continue the heat until it is dissolved; then add the elixir. This elixir should be freshly made when wanted. Each fluidram contains 5 gr. of sali- cylic acid. Elixir of Salicylic Acid, Compound. See Elixir of Salicylic, Compound. Elixir of Salicylate of Iron. Elixir of Salicylate of Iron, Com- pound. See combinations of elixirs containing iron. Elixir of Salicylate of Lithium. See Elixir of Lithium Salicylate. Elixir of Salicylates and Manaca. Sec Elixir of Manaca, etc. Elixir of Salicylate of Sodium. See Elixir of Sodium Salicylate. Elixir of Salicylate of Sodium, Com- pound. See Elixir Sodium Salicylate, Com- pound. Elixir of Salol. Salol gr. 300 Glycerin fl.oz. d,Vi Oil of curacao orange m. 30 Oil of lemon m. 22 Compound tincture of cud- bear m. 30 Alcohol (95 per cent.), to make fl.oz. 16 Dissolve the salol and oils in 7^ fluidounces of the alcohol; mix 2 fluid- ounces of the alcohol with the tincture and glycerin, and mix this with the salol solution. Then add enough alcohol to make 16 fluidounces, and filter. — Cine. Acad. Pharm. It is preferable to use absolute alcohol and dilute it to 95 per cent. Each fluidram contains nearly 2^ gr. of salol in clear solution. Elixir Saw Palmetto, Compound. Fluid extract of saw palmet- to fl.oz. 2 Fluid extract of sandalwood. fl.oz. 2 Fluid extract of corn silk... fl.oz. 4 Simple elixir fl.oz. 8 Mix and filter. Elixir of Senna. I. Deodorized fluid extract of senna fl.oz. 8 Compound tincture of carda- mom fl.oz. Yz Simple elixir fl.oz. 7^ II. Brit. Form. : Alexandria senna av.oz. 11 Sugar av.oz. 8 Chloroform m. 16 Oil of coriander drops 2 Tincture of capsicum m. 20 Alcohol, water, diluted alco- hol, each sufficient Mix 2V4. fluidounces of alcohol with 8*4 fluidounces of water, and with it evenly moisten the senna ; pack tightly in a closed vessel, macerate for 3 days, express forcibly, break up the marc, macerate it with enough more of the same kind of menstruum to furnish, in all, 11 fluidounces of liquid, express in 24 hours, mix the two liquids, add the sugar, heat in a closed vessel by means of a water bath to 94 deg. C, maintain at this temperature 10 minutes, allow to cool, strain, add the chloroform, tincture of capsicum, and oil of coriander, first mixed with 2 fluidrams of alcohol, and finally add, if necessary, enough of a mixture of 5 volumes of alcohol and 3 of water to make 16 fluidounces. PHARMACEUTICAL PREPARATIONS. 101 Elixir of Senna, Compound. Fluid extract of senna fl.oz. 2 Purified tamarind pulp. . . .av.oz. 4 Oil of coriander drops 12 Alcohol fl.dr. 2 Simple elixir, to make fl.oz. 16 Dissolve the oil in the alcohol, add to the fluid extract and pulp, then add the elixir. This is similar to confection of senna. Elixir of Senna, Magnesia and Rhu- barb. Elixir of Senna and Rhubarb. See Elixir of Rhubarb and its combi- nations. Elixir, Simple. By simple elixir is commonly under- stood a flavored and sweetened dilute alcohol, intended as a vehicle for medic- inal remedies, the flavoring agent being a volatile oil or combination of oils. The term may, however, include all such elixirs as are employed as vehicles, although these may be something more than a flavored and sweetened dilute al- cohol. If the second definition holds good, then the following elixirs, which have already been mentioned, will come un- der the head of simple elixirs : Elixir of orange, elixir of cherries, aromatic elixir, compound elixir of taraxacum, elixir de Garus, elixir of anise and ad- juvant elixir. Whenever simple elixir is mentioned, as an ingredient of a preparation in this formulary, some one of the elixirs that are prepared by simply flavoring and sweetening dilute alcohol should be se- lected, using such a one as will best disguise the taste of the medicament ; at times it will, of course, be found neces- sary or advantageous to employ one of the others, like compound elixir of ta- raxacum, elixir of cherries, etc. In case there be no preference whatever, the aromatic elixir of the U. S. P. should be used. It is suggested that a finer product will always be obtained by using de- odorized alcohol instead of ordinary al- cohol; also that no volatile oil be used which is not only perfectly pure, but also perfectly fresh. The favorite pre- dominant odor of simple elixir is that of orange peel. Formulas for making simple elixir other than the preceding are the follow- ing : I. Diehl's formula: Oil of orange peel m. 30 Oil of cinnamon drops 5 Oil of anise drops 2 Oil of bitter almond drop 1 'Tincture of cardamom. .. .fl.dr. 5 Alcohol fl.oz. 16 Water fl.oz. 36 Sugar av.oz. 24 Cocoa (Baker's) gr. 240 Magnesium carbonate . . . .av.oz. 1 Mix the oils, tincture and alcohol, and triturate with the cocoa and magnesium carbonate, having first mixed the latter intimately; transfer the mixture to a bottle, add the water gradually, agitate occasionally for several hours, filter, ex- press the filter between muslin, filter the expressed liquid, mix the two filtrates, in the liquid dissolve the sugar by agi- tation, and filter or strain as may be necessary. II. Schultz's formula: Oil of orange peel (fresh).. m. 48 Oil of lemon drops 12 Oil of coriander drops 3 Tincture of vanilla fl.oz. 1 Tincture of cardamom fl.oz. 1 Powdered chocolate (Ba- ker's) gr. 480 Alcohol fl.oz. 16 Simple syrup fl.oz. 24 Water (filtered through char- coal), to make fl.oz. 64 Dissolve the oils in 4 fluidounces of alcohol, add 12 fluidounces water and the remainder of the alcohol, and shake well. Dissolve the chocolate in 3 fluid- ounces of hot water, add the syrup, shake well, add the tinctures of carda- mom and vanilla, and enough water to make 64 fluidounces. Filter through pa- per, on which about x /i av. ounce of tal- cum has been distributed; return the first part until the filtrate is clear. 102 STANDARD FORMULARY OF III. Schmidt's formula: Oil of sweet orange Oil of caraway Spirit of cinnamon Alcohol Simple syrup Glycerin Distilled water Calcium phosphate Mix the oils and alcohol, cium phosphate, shake well, er ingredients, shake again, IV. Kimball's formula: . ..fl.oz. 2 . .drops 20 ..drops 32 . . .fl.oz. I4 1 A . . .fl.oz. 36 ...fl.oz. 8 ...fl.oz. 4 . .av.oz. \ l /2 add the cal- add the oth- and filter. Oil of orange peel fl.dr. 2}4 Oil of Ceylon cinnamon. . . .drops 3 Oil of anise drops 3 Oil of caraway drops 6 Tincture of vanilla fl.dr. 9 Sherry wine fl.oz. 3 Water fl.oz. 23 Simple syrup fl.oz. 26 Purified talcum av.oz. 1 Mix the oils with the talcum; mix the alcohol, wine and water, add to the mix- ture of talcum and oils, then add the vanilla and the syrup; let stand one hour, shaking often, and filter. V. Schnackenberg's formula: Soluble saccharin gr. 24 Oil of anise m. 160 Alcohol fl.oz. 16 Distilled water, to make. . .fl.oz. 64 Dissolve the saccharin in 40 fluid- ounces of water, add the oil of anise, previoi sly dissolved in 16 fluidounces of alcohol, and the remainder of the water. Add 1 av. ounce of purified talcum; let stand 24 hours, occasionally shaking, and filter. VI. Cinnamon water fl.oz. 24 Simple syrup fl.oz. 24 Alcohol fl.oz. 16 Spirit of orange fl.oz. 2 This may be clarified by shaking with paper pulp or purified talcum, and filter- ing. The pulp can be made by beating l A av.ounce filter paper in a mortar with sufficient water just to moisten it. If distilled cinnamon water be used, it makes a fine elixir. If distilled cinna- mon water cannot be had, the water should be made with oil of Ceylon cinna- mon. This is similar to the next formula. VII. Brit. Form.: Oil of bitter orange m. 96 Alcohol fl.oz. 19 Cinnamon water, distilled. . .fl.oz. 22J4 Simple syrup fl.oz. 22Y2 Dissolve the oil in the alcohol, add the other ingredients, filter through paper moistened with diluted alcohol, and well sprinkled with kaolin, returning the first portions of filtrate until it passes through bright. See also formula immediately prece- ding. VIII. Mclntyre's formula: Oil of orange peel fl.dr. 1 Oil of Ceylon cinnamon. . .drops 20 Alcohol fl.oz. 12 Simple syrup fl.oz. 25 Distilled water fl.oz. 27 Dissolve the oils in the alcohol, add the syrup to this solution until a milki- ness or slight precipitation of oil is pro- duced, then pour the mixture into the remaining syrup, constantly stirring dur- ing the whole process, and filter, using paper pulp or purified talcum, if neces- sary, to clarify. IX. Biroth's formula: Orange flower water fl.oz. 32 Bitter almond water fl.oz. 8 Simple syrup fl.oz. 8 Glycerin fl.oz. 8 Alcohol fl.oz. 8 Mix all and filter through purified tal- cum. X. Ceylon cinnamon gr. 90 Coriander gr. 90 Caraway gr. 90 Star-anise gr. 60 Nutmeg gr. 3° Oil of sweet orange peel m. 30 Diluted alcohol sufficient Simple syrup fl.oz. 32 Percolate the aromatics, previously re- duced to coarse powder, with diluted alcohol previously mixed with the oil of orange, continuing the percolation until 32 fluidounces of aromatic tincture are obtained, and mix with the syrup, filter- ing through talcum, if necessary. PHARMACEUTICAL PREPARATIONS. 103 XL Oil of sweet orange peel, .fl.dr. 2 Oil of caraway. fl.di. 1 Oil of coriander m. 40 Oil of cassia m. 40 Alcohol fl.oz. 16 Water fl.oz. 36 Sugar av.oz. 18 Purified talcum av.oz. 1 Mix the oils with the alcohol, add the water and sugar, shake till latter is dis- solved, add the talcum, shake again, and filter. XII. Oil of orange peel m. 70 Alcohol fl.oz. 28 Purified talcum gr. 120 Orange flower water fl.oz. 18 Simple syrup fl.oz. 18 Mix the oil and alcohol, add the tal- cum, shake well, add the other ingre- dients, shake again, and filter. XIII. Tincture of fresh orange peel fl.oz. 12 Tincture of fresh lemon peel. fl.oz. 4 Alcohol fl.oz. 8 Orange flower water fl.oz. 8 Purified talcum av.oz. 2 Simple syrup fl.oz. 32 Mix the whole well and filter. The tincture of fresh lemon peel is to be prepared like the tincture of orange peel, U. S. P. This and the preceding have been known as elixir of orange. XIV. Bitter orange peel av.oz. 1 Clove gr. 40 Canella gr. 40 Cinnamon water fl.oz. 24 Orange flower water fl.oz. 16 Holland gin fl.oz. 14 Sugar av.oz. 18 This is an old formula, quite different from any of the preceding. It is not recommended. Elixir of Six Bromids. See Elixirs of the Bromids. Elixir of Six Iodids. See Elixir of the Iodids. Elixir of Sodium Bromid. See Elixirs of the Bromids. Elixir of Sodium Bromid and Lu- pulin. See Elixir of Lupulin and its combi- nations. Elixir of Sodium Hypophosphite. See Elixir of Hypophosphite of So- dium. Other elixirs containing sodium hypo- phosphite may be found with Elixir of Calcium Hypophosphite and its combina- tions, and with Elixirs of the Hypophos- phites. Elixir of Sodium Hypophosphite. See Elixir of Hypophosphite of So- dium. Elixir of Sodium Salicylate. Sodium salicylate gr. 640 Syrup fl.oz. 3 Distilled water fl.oz. 7^ Aromatic elexir, to make. . .fl.oz. 16 Dissolve the sodium salicylate in the distilled water, add the syrup and elixir. Elixir of Sodium Salicylate, Com- pound. Sodium salicylate gr. 620 Fluidextract cimicifuga ..fl.oz. \y 2 Fluidextract gelsemium ...fl.dr. 2 Potassium iodid dr. 2 Purified talc dr. 2V 2 Aromatic elixir, to make.. fl.oz. 16 Dissolve the sodium salicylate and potassium iodide in 13 fluid ounces of aromatic elixir, add the fluidextracts and then sufficient aromatic elixir to make the product measure 16 fluid ounces. Then incorporate the purified talc, mix and filter, returning the first portions of the filtrate until it passes through clear. Store the product in dark amber-colored bottles.— N. F. The salicylic acid made from natural oil of wintergreen is preferable for this preparation. Keep in a cool, dark place. Elixir of Stillingia, Compound. I. Comp. fl. ext. of stillingia. .fl.oz. 4 Aromatic elixir fl.oz. 12 Mix them, allow the mixture to stand 104 STANDARD FORMULARY OF a few days, or longer, if convenient, and filter. Each fluidram represents 15 m. of compound fluid extract of stillingia. II. It may be prepared directly from the drugs as follows: Stillingia av.oz. 1 Turkey corn av.oz. 1 Blue flag av.oz. y 2 Elder flowers av.oz. y 2 Pipsissewa av.oz. x / 2 Coriander av.oz. J4 Prickly ash berries av.oz. y Aromatic elixir sufficient Mix the drugs, reduce to moderately coarse powder, moisten thoroughly with the elixir, let stand for several hours or over night, pack in a percolator, and pass elixir through it until 16 fluid- ounces of product have been obtained. Elixir of Strychnine Valerate. Strychnine valerate gr. \y Distilled water fl.dr. 1 x / 3 Tincture of vanilla fl.dr. 2 Comp. tincture of cudbear, .fl.dr. 2 Aromatic elixir, to make. . . .fl.oz. 16 Dissolve the strychnine valerate in the distilled water with the aid of heat, mix this solution with 15 fluid ounces aro- matic elixir. Then add the tinctures, and lastly, the remainder of the aromatic elixir. Filter, if necessary- — N. F. Each fluidram contains 1/100 gr. of strychnine valerate. Elixir of Sumbul. (Elixir of Musk Root.) Fluid extract of sumbul. .. .fl.oz. 2^/2 Alcohol fl.oz. 1 Adjuvant elixir fl.oz. 12^2 Purified talcum av.oz. l /> Triturate the fluid extract with the talcum, and the alcohol and elixir, and filter. Each fluidram represents about 10 gr. of sumbul. Elixir of Sumbul and Ammonium Valerianate. See Elixir of Ammonium Valerianate and its combinations. By way of comparison, see also No. II of the formulas immediately following. Elixir of Sumbul, Compound. I. Fluid extract of sumbul. .. .fl.oz. 2 Fluid extract of scullcap. .. .fl.oz. 1 Fluid extract of valerian. . .fl.dr. 2 Alcohol fl.oz. 1 Adjuvant elixir, to make. . .fl.oz. 16 Purified talcum av.oz. y 2 Mix the fluid extracts and alcohol, add the talcum, shake well, then add the elixir, shake again, and filter. Each fluidram represents 7 l / 2 gr. of sumbul, about 2 gr. of scullcap, and about x /l gr. of valerian. II. Fluid extract of sumbul fl.oz. 2 Alcohol fl.oz. 1 Elixir of ammonium valeri- anate fl.oz. 8 Simple elixir fl.oz. 5 Mix the fluid extract and alcohol, add the two elixirs, and filter through tal- cum. Each fluidram contains 1 gr. of ammo- nium valerianate and represents 7^ gr. of sumbul. These two mixtures are quite dissimi- lar, but both are dispensed under the name "compound elixir of sumbul." Elixir of Tar with Calcium and Sod- ium Hypophosphites. See Elixir of Calcium Hypophosphite and its combinations. Elixir of Tar, Compound. Syrup of wild cherry fl.oz. 3 Syrup of tolu fl.oz. 3 Morphine sulfate gr. 2^/2 Alcohol fl.dr. 6 Distilled water, hot m. 75 Wine of tar, to make fl.oz. 16 Dissolve the morphine sulfate in the water, add the syrups and alcohol and the wine of tar; allow to stand a day or two, if convenient, and filter if nec- essary. Each fluidram contains about 1/50 gr. of morphine sulfate. Elixir of Taraxacum, Compound. I. Fluid extract of dandelion. . .m. 256 Tincture of sweet orange peel fl.oz. 1 Fluid extract of wild cherry, .m. 150 PHARMACEUTICAL PREPARATIONS. 105 Fluid extract of licorice root fl.oz. i Tincture of cinnamon fl.dr. 4 Compound tincture of carda- mom fl.dr. 4 Aromatic elixir, to make. . .fl.oz. 16 Mix, let stand a few days, and filter. If a precipitate subsequently makes its appearance, it should be removed by filtration.— N. F. This elixir is intended chiefly as a vehicle or corrigent, to cover the bitter taste of quinine and similar. substances. II. Dandelion gr. 320 Wild cherry gr. 320 Sweet orange peel, recently- dried gr. 320 Licorice, Russian, peeled, .av.oz. 2^4 Cinnamon, Saigon gr. 80 Cardamom gr. 80 Canada snake root gr. 80 Caraway gr. 80 Clove gr. 27 Simple syrup fl.oz. 21 Alcohol, water, each sufficient Mix the drugs, reduce them to a mod- erately coarse powder, and extract by percolation with a mixture of 1 volume of alcohol and 2 of water, so as to ob- tain 11 fluidounces of percolate; to this add the syrup ; let stand a few days, if possible, and filter. — N. F. (1st edition). III. A formula for a preparation of the same name, which is also much in use and which is different in some re- spects from either of the preceding, is the following: Fluid extract of dandelion, .fl.dr. 5 Fluid extract of wild cherry. fl.dr. 3 Fluid extract of gentian. . . .fl.dr. 1 Fluid extract of licorice root fl.dr. 1 Simple elixir, to make fl.oz. 16 Mix and filter. Elixir of Terpin Hydrate. I. Terpin hydrate, fine powder.gr. 128 Tincture of sweet orange peel m. 75 Spirit of bitter almond m. 40 Alcohol fl.oz. 6V 2 Glycerin ....fl.oz. 6 l A Simple syrup, to make. .. .fl.oz. 16 Dissolve the terpin hydrate in the al- cohol, add the tincture, solution, glycerin and syrup. Mix well and filter, if nec- essary. — N. F. Each fluidram contains I gr. of terpin hydrate. II. Vigier's formula: Terpin, hydrate gr. 60 Tincture of vanilla fl.dr. 1 Alcohol fl.oz. 2 Glycerin fl.oz. 2 Honey fl.oz. 2 Elixir of Terpin Hydrate and Con- deine. Codeine gr. 16 Elixir of terpin hydrate fl.oz. 16 Dissolve the codeine in the elixir by trituration. — N. F. Each fluidram contains 1 gr. of terpin hydrate and % gr. of codeine. Elixir of Terpin Hydrate and Di- acetylmorphine. Diacetylmorphine hydrochl SY 2 Elixir of terpin hydrate. .. .fl.oz. 16 Dissolve the heroin in the elixir. — N. F. Each fluidram contains 1 gr. of terpin hydrate and 1/24 gr. of diacetylmorphine hydrochlor. Elixir of Turkey Corn, Compound. See Elixir of Corydalis, Compound. Elixirs Containing- Valerianate of _ Ammonium. All elixirs containing valerianate of ammonium may be found under the head of Elixir of Ammonium Valerianate. Elixir of Valerianate of Iron. See Elixir of Iron combinations. Elixir of Valerianates of Iron, Qui- nine and Zinc. — (Elixir of Three or Triple Valerianates.) Iron valerianate '.gr. 64 Quinine valerianate gr. 64 Zinc valerianate gr. 64 Tincture of cudbear fl.dr. 2 Valerianic acid sufficient Simple elixir, to make fl.oz. 16 Triturate the three valerianates with 8 fluidounces of elixir to a smooth paste, add, if necessary, a very small amount of the acid, just enough to dissolve the salts, then add the tincture and the re- mainder of the elixir, and filter. If too much valerianic acid has been 106 STANDARD FORMULARY OF added so that it is betrayed by its odor, it should be exactly neutralized by stir- ring with a glass rod repeatedly dipped in dilute ammonia water. Each fluidram contains Yz gr. each of the valerianates of iron, quinine and zinc. Elixir of Valerianate of Morphine. See Elixirs of Morphine combinations. Elixir of Valerianate of Quinine. Elixir of Valerianate of Quinine and Strychnine. See Elixir of Quinine and its combi- nations. See Elixir of Valerianate of Strych- nine. Elixir of Valerate of Zinc. Zinc valerate gr. 128 Citric acid gr. 124 Alcohol fl.oz. 2 Distilled water, q. s. Aromatic elixir, to make.. fl.oz. 16 Neutralize the citric acid with the stronger ammonia water, and add suffi- cient distilled water to make l l / 2 fl. ozs. of solution. Add 4 fluid ounces of aro- matic elixir and the alcohol and dissolve the zinc valerate in this mixture. Then add the spirit of bitter almond, the com- pound tincture of cudbear and finally sufficient aromatic elixir to make the product measure 16 fluid ounces.— N. F. Each fluidram contains i gr. of zinc valerianate. Elixir of Wafer Ash. (Elixir of Ptelea.) Fluid extract of wafer ash. .fl.oz. 2^ Simple elixir, to make fl.oz. 16 Mix, and allow to stand for about 24 hours, then filter through purified tal- cum. Each fluidram represents 1© gr. of wafer ash. Elixir of Wafer Ash, Bismuth and Pepsin. See Elixir of Bismuth and its combi- nations. Elixir of Wafer Ash and Pepsin. See Elixir of Pepsin and its combina- tions. Elixir of Wahoo. (Elixir of Euony- mus.) Fluid extract of wahoo fl.oz. 2 l / 2 Water fl.oz. 2 Syrup of coffee fl.oz. 2 Compound elixir of taraxa- cum fl.oz. gy 2 Mix them, let the mixture stand 48 hours, if convenient, and filter. Each fluidram represents about 9^ gr. of wahoo. Elixir of Wahoo and Blue Flag. See Elixir of Blue Flag and its com- binations. Elixir of White Pine, Compound. Fluid extract of white pine bark fl.oz. 1 Fluid extract of wild cerry bark fl.oz. 1 Fluid extract of balsam gil- ead buds fl.dr. Fluid extract of spikenard, .fl.dr. Fluid extract of bloodroot. .fl.dr. Fluid extract of sassafras. .. .m. Morphine acetate gr. 3 Chloroform m. 64 Alcohol fl.oz. 7 Water fl.oz. 4 Simple syrup fl.oz. 3 Mix the fluid extracts with the alcohol, water and syrup previously mixed, and filter through purified talcum until clear : add the chloroform and dissolve mor- phine salt in the mixture. The above represents the now well- known "white pine cough syrup" in elix- ir form. Elixir of Wild Cherry. Fluid extract of wild cherry.fl.oz. 4 Alcohol fl.oz. 1 Simple elixir fl.oz. 11 Mix, allow to stand for 24 hours, and filter through purified talcum. Each fluidram represents 15 gr. of wild cherry. Elixir of Wild Cherry and Iron. See Elixir of Iron and its combina- tions. 1 1 1 30 PHARMACEUTICAL PREPARATION S. 107 Elixir of Yerba Santa. (Elixir of Eriodictyon.) Fluid extract of yerba santa fl.oz. 2 Pumice stone, powder. .. .av.oz. i Magnesium, carbonate gr. 160 Alcohol fl.oz. i Simple elixir, to make fl.oz. 16 Triturate the fluid extract with the pumice and magnesium carbonate until well mixed, add the alcohol, mix again, then add 13 fluidounces of elixir, mix once more, let the whole stand for sev- eral hours, stirring occasionally, then fil- ter, returning the first portions of fil- trate to the filter until the liquid is clear, and finally adding enough simple elixir through the filter until the filtrate meas- ures the requisite amount. • Each fluidram represents 7^ gr. of yerba santa. Elixir, of Yerba Santa, Aromatic. Elixir Corrigens.) I. Fluid extract of yerba santa fl.oz. 1 Simple syrup fl.oz. 8 Pumice, fine powder and washed gr. 240 Magnesium carbonate gr. 75 Compound elixir of taraxa- cum, to make fl.oz. 16 Mix 7 fluidounces of the elixir with the syrup and pumice, then add the fluid extract, and mix the whole thoroughly by agitation. Shake the mixture occa- sionally during 2 hours, then allow it to settle, and carefully decant the liquid into a funnel, the neck of which con- tains a small pellet of absorbent cotton. Afterwards add the dregs and allow them to drain. To the filtrate add the magnesium carbonate, and shake occa- sionally during several hours. Let the mixture stand at rest during 12 hours, if convenient, then decant the liquid and filter it tnrough paper. To the fil- trate add enough compound elixir of taraxacum, if necessary, to make 16 .fluidounces. — N. F. This preparation is chiefly intended as a vehicle for quinine and other bitter remedies. .. II. Edel's formula modified : Yerba santa, coarse powder.. gr. 360 Sweet orange peel, recently dried and in coarse powder.gr. 120 Oil of clove drops 4 Oil of cinnamon drops 4 Oil of caraway drops 2 Oil of coriander drop 1 Comp. tinct. of cardamom, .fl.dr. 1 Sugar . .av.oz. 7 Glycerin, water, alcohol, so- lution of potassa, each, .sufficient Mix the oils and tincture with the drugs and extract by percolation in the usual way, employing as a menstruum a mixture of 1 part of alcohol, 1 of glycerin, and 3 of water, all by measure, with 1 per cent, of liquor potassa. 12 fluidounces of percolate are to be ob- tained, which is to be returned to the percolator if not clear ; to this add the sugar and dissolve by agitation. III. Yerba santa .av.oz. 1 Sweet orange peel gr. 144 Cardamom (without capsule) gr. 28 Clove gr. 28 Cinnamon gr. 28 Anise gr. 20 Coriander gr. 20 Caraway gr. 20 Red saunders gr. 10 Sugar av.oz. 7 Alcohol, glycerin, water, each sufficient Mix the drugs, reduce to moderately coarse powder, extract by percolation with a menstruum composed of 1 part of alcohol, 1 of glycerin, and 3 of water, all by measure, until 12 fluidounces of percolate are obtained ; in the latter, dis- solve the sugar by agitation, and filter. Elixir of Yerba Santa, Compound. Fluid extract of yerba santa. fl.oz. 1 Fluid extract of grindelia. .fl.oz. 1 Alcohol fl.oz. 1 Pumice stone, powder. ... .av.oz. 1 Simple elixir, to make fl.oz. 16 Mix the fluid extracts, triturate with pumice stone, add 13 fluidounces of sim- ple elixir, mix again, allow the whole to stand for several hours, stirring occa- sionally, and filter. Each fluidram represents nearly 4 gr. each of yerba santa and grindelia. 108 STANDARD FORMULARY OF Elixir of Zinc Bromid. See Elixirs of the Bromids. Elixir of Zinc, Iron and Quinine Valerianate. Elixir of Zinc Valerianate. See the elixirs of the valerianates. Emulsions and Emulsifiers. The N. F. states that the successful formation of emulsions, whether of fix- ed or volatile oils, is most .satisfactorily and expeditiously accomplished with powdered acacia as the emulsifying agent. Hence, preference is given acacia, though other emulsifying agents are not ignored. When acacia is used as the emulsify- ing agent of fixed oils, it is important that the oil, the acacia and the water shall primarily be in absolutely definite proportion to each other by weight. This proportion is 8 parts of oil, 2 parts of acacia, and 3 parts of water. The oil and acacia, the latter in fine powder, are weighed into a mortar, and well mixed by trituration ; the water is then added in one portion, and the whole is triturated briskly until a thick, creamy emulsion is produced, the sides of the mortar being carefully scraped, and the mixture again triturated so as to insure the complete emulsification of all the oil. During warm weather, the water and oil should be cooled. The other ingredients may then be gradual- ly added ; first the flavoring, then the greater part of the water necessary to make the final quantity, then the syrup, etc. Finally the quantity is adjusted by the addition of sufficient water. Alcoholic liquids should be added last and should be previously mixed with a portion of the water. If these simple conditions and direc- tions are carefully observed, and par- ticularly if the proportions by weight are accurate, a perfect emulsion is ob- tained with certainty and rapidity. In making emulsions of volatile oils, the use of tragacanth, or of tragacanth and acacia mixed, is more satisfactory than acacia alone, despite the above statement of the N. F. Even in mak- ing emulsions of fixed oils it is desirable to add a small amount of powdered tragacanth ; this gives more "body" to the emulsion and, if used in proper pro- portion, the emulsion will not separate in the least. Large manufacturers of cod-liver oil emulsions habitually use a mixture of acacia and tragacanth as the emulsifier. A mixture of Irish moss mucilage and acacia is also a favorite. Less acacia is required if tragacanth or Irish moss mucilage be employed in connection with it. With other emulsifying agents — muci- lage of Irish moss, mucilage of dex- trin, glycerite of yolk egg (glyconin), tincture of soap bark — the proportions need not be adjusted with the same minuteness. It suffices to place the emulsifier into a bottle or mortar, and to add the oil in small portions at a time, shaking or triturating briskly after each addition until emulsification is completed. Obviously the preparation of this class of emulsions is very much fa- cilitated by mechanical contrivances that are capable of producing brisk agitation and mingling of the two fluids, and such are necessarily resorted to when emul- sions are to be made in large quantities for the market. The above-mentioned emulsifiers do not, by any means, include all those known, nor even all those commonly accepted. Extract of malt is an excellent emulsifier for fixed oils, and formulas for combinations of malt extract with cod liver oil will be found under Ex- tract of Malt, which see. Powdered gum tragacanth may also be used as an emulsifier but while it is fairly satisfactory for volatile oils, ■ it alone is scarcely efficient for fixed oils. Besides the quality of available powder- ed tragacanth is exceedingly variable This latter statement also applies to powdered acacia of which only the very best quality should be employed. Saccharated casein is an excellent PHARMACEUTICAL PREPARATIONS. 109 emulsifier of fixed oils. It is prepared by heating any suitable quantity of cow's milk, say, one gallon, to 40 deg. G, adding 2 fluidounces of 10 p. c. ammonia water, or somewhat more if the ammonia water be weaker, and set- ting aside in a separatory funnel for 24 hours. Then draw off the lower limpid layer, the so-called "lactoserum," from the upper layer of partially saponified cream or fat. To this lactoserum add acetic acid until no further precipita- tion occurs. Wash the precipitate re- peatedly with water at a temperature of 35 to 40 deg. C. until the water is no longer acid. Then collect the precipi- tate on a muslin strainer and press it to remove excess of water. In the re- sulting cake, determine the proportion of actual casein by drying a small weighed portion in a drying oven at no deg. C. Now triturate the moist cake of casein with 4 av. ounces of powdered sugar until well mixed, and then incorporate 8 parts of sodium bi- carbonate for every 100 parts of casein calculated as dry. Under the influence of prolonged trituration, in the pres- ence of the sodium bicarbonate, the casein swells up and becomes thinner, translucent, and soluble in water. On no account must the bicarbonate be added directly to the casein as a tough, unmanageable mass would result. Add more powdered sugar until there are 9 parts by weight of powdered sugar for every 1 part of casein calculated as dry. A mixture of about the consistence of lozenge paste is formed, which should be divided into small fragments, well dried at a temperature of 25 to 30kdeg. C, powdered fine, and enough powdered sugar added, if necessary, to make the whole weigh 10 times as much as the weight of the casein in the original moist mass calculated as dry. Still other emulsifying agents are condensed milk, gelatin, egg yolk, muci- lages of acacia and linseed, etc. Some- times it is of advantage to combine two emulsifiers. The latest recommended emulsifier is saponin, the active prin- ciple soap bark and soapwort. Finally, there are also a number of proprietary emulsifiers on the market which are in powder form. The advan- tages claimed for these are that the emulsion may be produced by agitation in a bottle, that the emulsion is per- manent, and that only a small quantity of the emulsifier is required (in some cases 4 drams is sufficient to make one pint of emulsion which may contain as much as 50 per cent, of oil). The following mixtures will equal the above referred-to proprietary emulsi- fiers: I. Equal parts of acacia, tragacanth, sugar and corn starch, all to be in fine powder, and the gums to be of the best quality. Mix well. n. Saccharin parts 3 Saponin parts 13 Tragacanth powder parts 200 Mix well. III. Gelatin, No. 80 powder part I Tragacanth, powder part 1 Sugar, powder parts 2 Mix well. For typical formulas for emulsions of fixed oils, see the emulsions of cod-liver oil, and for typical formulas for emul- sions of volatile oils, see emulsions of turpentine oil. For methods of emul- sifying other substances, such as chloro- form, camphor, etc., see the formulas for emulsions which follow. The above hints and suggestions re- fer only to emulsions made with an added emulsifier. Emulsions may also be made of substances which contain not only the oil or resin to be emulsi- fied, but also the emulsifying agent. Examples of such substances are gum- resins and seeds. See Emulsion of Ammoniac and of Asafetida for ex- amples of gum-resin emulsions and manner of making the same ; and see Emulsion of Almond and of Pumpkin Seed for examples of seed emulsions 110 STANDARD FORMULARY OF and manner of making the same. The German and Austrian pharmacopeias direct that when no directions are given for making a seed emulsion, the product should represent io p. c. by weight of seed (equivalent to i pint of emulsion from i}i av. ounces of seed). All emulsions may be flavored with volatile oils, flavoring syrups, or other- wise. This will be explained in detail under Emulsion of Cod-Liver Oil, which see. All emulsions should be shaken before use. Emulsion of Almond. (Almond Mix- ture U. S. P. 1880. — Simple Emulsion. — Milk of Almond. — Almond Milk. — Emulsum Amyg- dalae. — Emulsio Simplex. — Emul- sio Amygdalarum Saccharata.) I. Sweet almond av.oz. I Acacia, fine powder gr. 75 Sugar av.oz. l / 2 Water, to make fl.oz. 16 Having blanched the almonds with hot water, add the acacia and sugar, and beat in a mortar until well mixed. Then rub this with 14^2 fluidounces of water, at first very gradually added, until a uniform mixture results. Strain this and wash the mortar and strainer with enough water to make the cola- ture measure 16 fluidounces. The first portions of water should be added very slowly, making a uniform paste before adding more water. This preparation should be freshly made when wanted for use. — U. S. P. II. Sweet almond gr. 365 SW 1 ; • gr. 365 Distilled water fl.oz. 16 Blanch almonds in the usual way, triturate with a little sugar, then with a little water gradually added, then slowlv add the remainder of the water, mix well, strain with expression, and in the colature dissolve the remainder of the sugar. — Codex. III. Sweet almond av.oz. \Y\ Sugar av.oz. 1^4 Distilled water sufficient From the almond prepare an emulsion in the usual manner, so as to obtain 15 fluidounces of emulsion, and in this dissolve the sugar by agitation. — Germ. Form. IV. Sweet almond, blanched, .av.oz. \Y\ Sugar av.oz. 1 Water enough to make fl.oz. 16 Triturate the almond with the sugar and prepare an emulsion in the usual manner. — Austr. Pharm. V. Brit. Pharm. — Same as Mixture, Almond, which see. VI. The following is also called "emulsion of almond/' "but is also known as "look album," "white linctus.'' or "white drink": Sweet almond av.oz. 2>V\ Bitter almond - gr. 90 Sugar, granulated av.oz. zVa Tragacanth, fine powder gr. 24 Orange flower water fl.dr. 9 Distilled water fl.oz. 12 Make an emulsion with the almonds, 4 fluidounces of water, and nearly the whole of the sugar, and strain. Tritu- rate the tragacanth with the rest of sugar, then add small portion of the emulsion, and triturate briskly and for a long time, until well mixed; then add the remainder of the emulsion in small portions, while continuing the tritura- tion, and finally add the orange flower water. Emulsion of Almond Oil. (Oil Emul- sion. — Emulsio Oleosa. — Simple Emulsion.) Sweet almond oil fl.oz. iVa, Gum arabic, powder gr. 365 Distilled water fl.oz. 13^ Triturate oil with gum until well mixed, emulsify with i J / 2 fluidounces of water, and then gradually incorporate the balance of the water. This contains about 10 per cent of oil.— Germ. Pharm. PHARMACEUTICAL PREPARATIONS. Ill Emulsion of Almond, Compound. (Compound Almond Milk.) Sweet almond, blanched, .av.oz. i l / 2 Henbane seed gr. 130 Calcined magnesia gr. 130 Sugar, powder av.oz. V/ 2 Bitter almond water. . . . -. .fl.dr. 6 Water fl.oz. 13K' From the sweet almond and henbane seeds, prepare an emulsion with the water, strain, add the matter almond water, mix the magnesia and sugar with this emulsion, and shake until the sugar is dissolved. — Germ. Form. Emulsion of Ammoniac. (Mixture of Ammoniac, U. S. P. 1880.— Milk of Ammoniac. — Lac Am- moniac.) Gum ammoniac gr. 300 Water to make fl.oz. 16 Rub the gum in a mortar with 14^ fluidounces of water, at first very grad- ually added, until a uniform emulsion results. Then strain the mixture and wash the mortar and strainer with enough water to make the product measure 16 fluidounces. This should be made freshly when wanted for use. This contains about 4 per cent, of ammoniac— U. S. P. 1890. The mixture of ammoniac of the Brit. Pharm. is made from 225 grains of ammoniac, 1 fluidounce of syrup of tolu and 15 fluidounces of distilled water. Emulsion of Asafetida. (Asafetida Mixture U. S. P. 1880.— Milk of Asafetida. — Lac Asafetida.) Made like emulsion of ammoniac, substituting asafetida in selected tears for the ammoniac. — U. S. P. Emulsion Camphorated. I. Camphor gr. 15 Alcohol drops 25 Acacia, powder gr. 75 Sugar, powder gr. 365 Emulsion of almond fl.oz. 8 Reduce the camphor to fine powder by trituration with the alcohol, then add the acacia and incorporate thor- oughly, next add the sugar, and finally the almond emulsion. — H. II. Sweet almond, blanched. ...gr. 365 Sugar gr. 365 Camphor water fl.oz. jY 2 Make an emulsion of the almonds with the water, strain, and dissolve the sugar in the colature. — D. III. Camphor may also be emulsi- fied by dissolving it in oil (the official liniment of camphor may be used) and making an emulsion of this solution in the usual manner for fixed oils. For an emulsion which contains cam- phor with chloroform, see Emulsion of Chloroform, No. III. Emulsion of Castor Oil. I. Castor oil av.oz. 5% Acacia, fine powder gr. 575 Tincture of vanilla fl.dr. 3^ Simple syrup fl.oz. s l / 2 Water to make fl.oz. 16 Carefully weigh the castor oil and the acacia into a mortar, triturate until well mixed; then add 2 fluidounces of water all at once to the mixture of oil and acacia, triturating briskly until a thick, creamy emulsion is produced. To this add gradually with stirring, a mixture of the syrup and tincture with a por- tion of the remaining water, and finally enough water to make 16 fluidounces. — N. F. This emulsion contains about 1/3 its volume of oil. The flavoring may be varied to suit. The preparation should be freshly prepared as required. See also Emulsion of Castor Oil, Palatable. II. This makes an excellent emul- sion of castor oil much stronger than the preceding: Castor oil fl.oz. 11 Egg yolk fl.oz. 2 Syrup fl.oz. 3 Oil of cassia fl.dr. i l / 2 Beat the yolk thoroughly in a mortar, add the two oils, triturate until emulsi- fied, and finally add the syrup. 112 STANDARD FORMULARY OF III. The following is the castor oil mixture of the Brit. Pharm. : Castor oil fl.oz. 6 Mucilage of acacia fl.oz. 3 Orange flower water, stronger fl.oz. 2 Cinnamon water fl.oz. 5 Mix the two waters, place the muci : lage into a mortar and add to it, alter- nately, in portions, the oil and the waters, with constant trituration. Emulsion of Castor Oil, Palatable. Castor oil av.oz. 8 White of 3 eggs, or about, .fl.dr. 13 Sugar av.oz. 4 Oil of cinnamon drops 15 Water, to make fl.oz. 16 Emulsify the oils in a mortar with the egg white and ij^ fluidounces of water, in this dissolve the sugar by agi- tation, strain through a moistened straining cloth, and add enough water through the strainer to make 16 fluid- ounces. Should be freshly made when wanted. This contains 50 per cent, of castor oil. — Cine. Acad. Pharm. Emulsion of Chian Turpentine, Dr. Clay's. Chian turpentine gr. 120 Stronger ether fl.dr. 4 Mucilage of acacia fl.oz. 4 Glycerite of yolk of egg. ..fl.oz. 2 Simple syrup fl.oz. 1 Sulfur gr. 40 Cinnamon water, to make, .fl.oz. 16 Dissolve the turpentine in the ether, mix the mucilage with the glycerite in a mortar, add the ethereal liquid, and triturate until emulsified. Triturate the sulfur with the syrup, incorporate this with the emulsion, and then add the cinnamon water. Emulsion of Chloroform. (Chloro- form Mixture U. S. P. 1880.) I. Chloroform m. 80 Sweet almond oil fl.dr. 2 Tragacanth, very fine powder.gr. 20 Water, to make fl.oz. 4 Introduce the tragacanth into a per- fectly dry bottle of sufficient capacity, add the chloroform, and shake the bot- tle thoroughly so that every part of the interior surface may become wetted. Then add about 1 fluidounce of water and incorporate it by vigorous shak- ing. Next add the oil, in several por- tions, shaking after each addition, and when the oil has become thoroughlv emulsified, add enough water, in divid- ed portions, shaking after each addi- tion, until the product measures 4 fluid- ounces. — U. S. P. The above involved procedure is un- necessary. An equally efficient and more convenient method of emulsifying the chloroform is to mix it with all the oil in a suitable bottle, turn the bottle about so as to moisten every portion of its interior with the oily mixture, then introduce the tragacanth, agitate until well mixed, then add, all at once, 3 fluidounces of water, agitate the whole thoroughly until well mixed, and finallv incorporate the remainder of the water. Each fluidram contains 2.y 2 m. of chloroform. The N. F., 1st edition, and the U. S. P. 1880 also recognized emulsions of chloroform. II. Chloroform m. 80 Tincture of soap bark fl.dr. 1 Acacia, fine powder gr. 24 Water, to make fl.oz. 4 Put the chloroform and tincture into a 4-ounce bottle, add the acacia, shake well, add the water, and again shake well.— N. F. (1 st Edit.). III. Ihe U. S. P. 1880 recognized a compound emulsion of chloroform un- der the name "chloroform mixture." The formula was as follows : Chloroform fl.dr. 2 Camphor gr. 45 Yolk of egg fl.dr. 4 Distilled water fl.oz. ^H Rub the yolk, first by itself in a mor- tar, then with the camphor previously dissolved in the chloroform, and finally the water gradually added so as to make a uniform mixture. This contains about 8 per cent, by weight of chloroform and about 2 per PHARMACEUTICAL PREPARATIONS. 113 cent, of camphor, or each fluidram con- tains about ZV2 rn. of chloroform and about i*4 g r - of camphor. Emulsion of Cod Liver Oil. The U. S. P. recognizes one emul- sion of cod liver oil, which is made with acacia, while the N. F. recognizes four emulsions of cod liver oil made with acacia, mucilage of Irish moss, glycerite of yolk of egg, and dextrin mucilage. These emulsions may be plain; that is, may consist simply of oil, emulsifier, water, sugar and flavor- ing, or they may be combined with other agents, such as hypophosphites,' phosphates, lactophosphates, phosphorus, creosote, etc., or perhaps with two or more such agents. The method adopted in incorporating these medicaments varies according to its character; if it be soluble in the oil, it is added to the latter before emulsifying, and if soluble in water it is dissolved in the latter be- fore it is added to the mixture of gum and oil. Should, however, the sub- stance not be soluble in either the oil or water, then other methods still must be adopted ; if it be solid in character, it should be triturated to a very fine powder and be added to the emulsion; if it be an alcoholic liquid, like tincture of benzoin or spirit of nitrous ether, it is generally best to add it to the emulsion after all the water has been added. Flavoring. — Emulsions of cod-liver oil usually require flavoring, and this con- sists most frequently in the addition of a volatile oil, like cassia, wintergreen, bitter almond, sassafras, etc., which should be added to the oil before emul- sification, or it may consist of a flavored syrup like syrup of tolu, which should be incorporated with the emulsion after most of the water has been added. No objection can be made to using two or three flavoring agents. Since no single or compound aromatic can be devised which would be accept- able under all circumstances as a flavor- ing for emulsion of cod-liver oil, the selection of the most suitable aromatic must be left to the prescriber or dis- penser. Among those which are found to be most serviceable, according to the N. R, are the following, the quan- tities given below being intended for 16 fluidounces of finished emulsion, though in some cases a smaller or a larger quantity, in the same proportions, may be preferable: 1. Oil of wintergreen m. 30 2. Oil of wintergreen m. 15 Oil of sassafras m. 15 3. Compound spirit of orange... m. 15 4. Oil of wintergreen m. 15 Oil of bitter almond, .drops 4 to 6 Oil of coriander drops 4 to 6 5. Oil of wintergreen. m. 15 Oil of sassafras m. 15 Oil of bitter almond, .drops 4 to 6 6. Oil of wintergreen m. 20 Oil of bitter almond. , m. 20 7. Oil of neroli m. 15 Oil of bitter almond. m. 15 Oil of clove drops 4 to 6 Preservation. — When an emulsion of cod-liver oil is to be kept for some time, its deterioration may be prevented or retarded by the addition of 1 fluid- ounce of alcohol in the place of the same quantity of water, when making 16 fluidounces of emulsion. The emulsions here given are made with the use of different emulsifying agents and different flavoring agents, but no one need be restricted to the use of such of either as may be men- tioned. In the formulas for acacia cod-liver oil emulsions taken from the N. F., the proportions of oil and acacia relative to the total ammount have been slightly increased; the N. F. directs 464 grams of oil and 116 of acacia to make 1000 cc, where as this work directs 8 av. ounces of oil and 2 of acacia to make 16 fluidounces. The slight increase makes no difference and conveniently rounds out the quantities. 114 STANDARD FORMULARY OF I. Acacia emulsion (of the U. S. P.) : Cod liver oil fl.oz. 8 Acacia, fine powder av.oz. 2 Simple syrup fl.dr. 13 Oil of wintergreen m. 30 Water to make fl.oz. 16 Rub the acacia with the cod liver oil in a dry mortar until uniformly mixed, then add at once 4 fluidounces of water, and triturate lightly and rapidly until a thick, homogeneous emulsion is pro- duced; to this add the oil of winter- green and enough water to make 16 fluidounces, and mix thoroughly. The oil of wintergreen may be re- placed if desired by a suitable quantity of oil of bitter almond or other suit- able flavoring. II. Acacia emulsion (preferred form- ula of N. F.) : Cod-liver oil av.oz. 8 Acacia, fine powder av.oz. 2 Syrup of tolu v . fl.dr. 13 Flavoring (any desired kind, see above) sufficient Water to make fl.oz. 16 Triturate oil and acacia together thoroughly in a mortar, add 3 fluid- ounces of water all at once to the mix- ture of oil and acacia, triturating brisk- ly until a thick, creamy emulsion is pro- duced. To this add the flavoring and syrup and then the remainder of the water. The 1st N. F. directed 8 fluidounces of oil, 720 grains of acacia, 2 fluid- ounces of syrup of tolu, desired flavor- ing, and water to make 16 fluidounces. Emulsion of cod-liver oil may also be prepared by any other method capable of emulsifying oil, the following form- ulas being given as examples : III. Irish Moss Emulsion : Cod-liver oil fl.oz. 8 Mucilage of Irish moss fl.oz. 5 Syrup of tolu fl.dr. 13 Flavoring (any desired kind, see above) sufficient Water to make fl.oz. 16 Pour the mucilage into a suitable bottle, add the oil in divided portions, shaking well after each addition, and when a perfect emulsion is formed, add the syrup and flavoring, and lastly, enough water to make 16 fluidounces. Finally, mix the whole thoroughly to- gether. — N. F. This was the preferred formula of the 1 st N. F. but the acacia emulsion is now preferred. IV. Glyconin Emulsion : Cod-liver oil fl.oz. 8 Glycerite of yolk of egg. . . .fl.oz. 2^4 Syrup of tolu fl.dr. 13 Flavoring (any desired kind, see above) sufficient Water, to make fl.oz. 16 Triturate the glycerite (glyconin) in a mortar with the oil, added in small portions at a time, and thoroughly in- corporate each portion before adding the next. Then, continuing the tritura- tion, gradually add the syrup and flav- oring. Finally add enough water to make 16 fluidounces, and mix the whole thoroughly together. — N. F. V. Dextrin Emulsion: Cod-liver oil fl.oz. 8 Mucilage of dextrin fl.oz. 5% Syrup of tolu fl.oz. 2 Flavoring (any desired kind, see above) sufficient Water, to make fl.oz. 16 To the mucilage contained in a suit- able bottle add the oil, first in small portions, agitating each time, until the last added portion is emulsified. Then add the flavoring, the syrup and lastly, enough water to make 16 fluidounces, and mix the whole thoroughly together. VI. Quillaja Emulsion: Cod-liver oil fl.oz. 8 Tincture of soap-bark fl.oz. 1 Syrup of tolu fl.dr. 13 Flavoring (any desired kind. see above) sufficient Water to make fl.oz. 16 Pour the tincture into a suitable bot- tle, then add the oil in portions of about 2 fluidounces each, and shake after each addition until a perfect emulsion results. Next add the syrup and the flavoring, and lastly, enough water to make 16 fluidounces. Finally, mix the PHARMACEUTICAL PREPARATIONS. 115 whole thoroughly together. — Former N. F. An 85 per cent, emulsion of cod-liver oil may be prepared by mixing in the manner just prescribed: Cod-liver oil fl.oz.13H Tincture of soap-bark fl.dr. 13 Flavoring (any desired kind, see above) sufficient Syrup of tolu to make fl.oz. 16 Emulsion of cod-liver oil made with quillaja should not be dispensed without the direction or consent of the pre- scriber. In fact, these formulas are only given here in deference to the N. F. ; they should never be used. VII. Condensed Milk Emulsion: Cod-liver oil fl.oz. 8 Condensed milk av.oz. 6 Oil of sassafras drops 10 Oil of wintergreen drops 10 Oil of bitter almond drops 2 Glycerin fl.oz. 1 Water, to make fl.oz. 16 Add the oil in divided portions to the condensed milk, taking care that each portion of oil is well emulsified before adding another portion. Occa- sionally where the emulsion becomes too thick, a small quantity of water may be added. Then incorporate the flavor- ing oils, the glycerin, and the remain- der of the water. Only the thick condensed milk can be used as an emulsifier ; the non-sac- charated kind is unsuited for this pur- pose. VIII. Cod-liver oil fl.oz. 8 Yolk of two eggs, Tragacanth, powder gr. 16 Elixir of saccharin fl.dr. 1 Tincture of benzoin fl.dr. 1 Spirit of chloroform fl.dr. 4 Oil of bitter almond m. 8 Distilled water, to make. .. .fl.oz. 16 — Brit. Form. Measure 5 fluidounces of distilled water, place the powdered tragacanth in a dry mortar, and triturate with a little of the cod-liver oil; then add the egg-yolk and stir briskly, adding water as the mixture thickens. When of a suitable consistence, add the remainder of the oil and water alternately, with constant stirring, avoiding frothing. Transfer to a pint bottle, add the elixir of saccharin, tincture of benzoin, spirit of chloroform, and oil of almond, prev- iously mixed, shake well, and add dis- tilled water, if necessary, to make 16 fluidounces. Instead of the elixir of saccharin, the solution of saccharin, N. F., may be em- ployed. IX. Lime Emulsion: Cod-liver oil fl.oz. 8 Lime water fl.oz. 4 Tincture of soap-bark. ... .fl.dr. 4 Glycerin fl.oz. 1 Oil of wintergreen drops 15 Oil of sassafras drops 15 Oil of anise drops 15 Mucilage of acacia, Irish moss or dextrin, to make. fl.oz. 16 Agitate the oil, water and tincture to- gether in a bottle until well mixed, then add the glycerin arid volatile oils, shake again, and finally add the muci- lage and shake again. X. Acacia and Tragacanth Emulsion: Acacia, powder gr. 60 Tragacanth, powder gr. 60 Starch, powder gr. 60 Cod-liver oil fl.oz. 8 Simple syrup fl.oz. 2 Oil of bitter almond drops 10 Water to make fl.oz. 16 Triturate the powders thoroughly with the cod-liver oil, then add gradu- ally $Vz fluidounces, triturating con- stantly, incorporate the almond oil and syrup, and finally add enough water to make 16 fluidounces of product. XL Saccharated Casein Emulsion: - Cod-liver oil fl.oz. 8 Saccharated casein av.oz. 4 Water to make fl.oz. 16 Triturate the casein with 4 fluid- ounces of water until well mixed, then add the oil in divided portions, being careful that each portion is emulsified before adding more. Occasionally, as the mixture becomes too thick, a small amount of water must be added. Fin- ally add enough water to make 16 fluidounces. Ilfi STANDARD FORMULARY OF XTI. Egg Emulsion: For examples of egg emulsions of cod-liver oil see Nos. Ill and VII, or prepare as follows: Cod-liver oil fl.oz. 8 Yolk of egg fl.oz. 2 Simple syrup fl.oz. 2 Water fl.oz. 4 Thoroughly triturate the oil in a suitable mortar, gradually incorporate the oil, emulsifying each portion before more is added, then incorporate the water and finally the syrup. XIII. Chocolate Emulsion : A so-called chocolate emulsion of cod- liver oil may be prepared by emulsifying 8 fluidounces cod-liver oil with acacia, mucilage of Irish moss or mucilage of dextrin in the usual manner as de- scribed above, then adding ^ to 1 av. ounce of powdered cocoa or chocolate, about 2 fluidounces of simple syrup, 2 to 4 fluidrams of tincture of vanilla, and enough water to make 16 fluid- ounces. XIV. The emulsions of cod-liver oil with malt extract are considered un- der Extract of Malt, which see. Emulsion of Cod-Liver Oil with Coca. I. Stronger emulsions of cod- liver oil fl.oz. 14 Elixir of coca fl.oz. 2 Oil of clove drops 24 Add the elixir and oil gradually to the emulsion, shaking thoroughly after ich addition. Each fluidram represents nearly 1 gr. of coca. II. Prepare an emulsion like any o^ those mentioned under Emulsion of Cod-Liver Oil. replacing 2 fluidounces of water by elixir of coca, and flavoring in any desired manner. Emulsion of Cod Liver, Compound. (Egg Emulsion of Cod-Liver Oil with Creosote and Iron.) Cod-liver oil av.oz 5^ Yolk of egg (about 12).. fl.oz. 5 Creosote fl.dr. 3 Sweet almond, blanched gr. 300 Brandy fl.oz. 2^2 Solution of iron peptonate (Cine. Acad. Pharm.) . .fl.oz. 2> l A Oil of bitter almond drops 5 Oil of lemon drops 5 Distilled water fl.dr. 11 Simple syrup to make fl.oz. 16 Rub the almond to powder, add wa- ter gradually to make a smooth paste, add the creosote, emulsify the latter by trituration, add the remainder of the water, and strain. Beat the yolk of egg with the brandy to a smooth mixture, and gradually add the oils so as to emulsify well. Then to this add the creosote emulsion and the solution of iron peptonate, mix well, and incorporate enough syrup to make 16 fluidounces. — Cine. Acad. Pharm. This preparation should be freshly prepared when wanted. Each fluidram contains about 20 drops of cod-liver oil, \ l /z drops of creo- sote and 6 drops of solution of iron peptonate. Emulsion of Cod-Liver Oil with Cre- osote and Hypophosphites. Cod-liver oil fl.oz. 8 Creosote, pure (beech- wood) fl.dr. 2 Acacia, powder av.oz. 2 Calcium hypophosphite gr. 128 Sodium hypophosphite gr. 128 Oil of wintergreen m. 30 Oil of sassafras m. 30 Oil of cinnamon m. 30 Glycerin fl.oz. 1 Syrup of orange fl.dr. 4 Distilled water, to make. . .fl.oz. 16 Mix the cod-liver oil, creosote, and essential oils, with the acacia, in a dry mortar ; dissolve the hypophosphites in 3 fluidounces of water, pour the solu- tion, all at once, into the other mix- ture, and stir briskly in one direction with the pestle until emulsification takes place; then add the glycerin, syrup and enough water to make 16 fluidounces. Each fluidram contains about 1 drop of creosote and 1 gr. each of hypophos- phites. PHARMACEUTICAL PREPARATIONS. 117 Emulsion of Cod-Liver Oil with Hypophosphites. I. Cod-liver oil fl.oz. 8 Acacia, fine powder av.oz. 2 Calcium hypophosphite gr. 36 Potassium hypophosphite. .. .gr. 18 Sodium hypophosphite gr. 18 Simple syrup fl.dr. 13 Oil of wintergreen m. 30 Water, to make fl.oz. 16 Rub the acacia with the cod-liver oil in a dry mortar until uniformly mixed, then add at once 4 fluidounces of water and triturate lightly and rapidly until a thick, homogenous emulsion is produc- ed, add the oil of wintergreen and in- corporate thoroughly. Dissolve the three hypophosphites in 13 fluidrams of water, mix the solution with the syrup, and add the liquid gradually to the emulsion with continued trituration. Lastly, add enough water to make the product measure 16 flidounces, and mix thoroughly. — N. F. II. Cod-liver oil av.oz. 8 Acacia, fine powder av.oz. 2 Any soluble hypophosphite (calcium, sodium, or po- tassium) gr. 128 Syrup of tolu fl.dr. 13 Flavoring (any desired kind, see above) sufficient Water, to make.. ...fl.oz. 16 Emulsify the oil with the acacia and 3 fluidounces of water, and add the flavoring. Then dissolve the hypophos- phite in sufficient water, mix this solu- tion with the syrup, and add the mix- ture gradually to the emulsified oil; lastly, add enough water to make 16 fluidounces, and mix the whole thor- oughly. If several hypophosphites are requir- ed, and no definite quantity is directed, equal parts of them may be used, amounting altogether to 128 gr. for the above formula. Varying quantities, larger or smaller than the above, may, of course, be used upon prescription. — N. F. (1 st Edit). The above is intended only as an ex- ample of this kind of a combination. Each fluidram contains 1 gr. of hypo- phosphite. III. Stronger emulsion of cod- liver oil fl.oz. 14 Oil of sassafras m. 15 Oil of wintergreen m. 15 Any soluble hypophosphitc.gr. 128 Water fl.oz. 2 Agitate the emulsion with the oils, then with the water containing the hypophosphite in solution. Emulsion of Cod-Liver Oil with Hypophosphite of Calcium. Prepare like the preceding, using 128 gr. of calcium hypophosphite for every 16 fluidounces of emulsion. Emulsion of Cod-Liver Oil with Hypophosphites of Calcium, and Sodium. Prepare like the preceding but using 64 grains each of the hypophosphites of calcium and sodium instead of the other hypophosphite. Emulsion of Cod-Liver Oil with Hypophosphites of Calcium, So- dium and Potassium. Stronger emulsion of cod- liver oil fl.oz. 12 Calcium hypophosphite gr. 128 Sodium hypophosphite gr. 96 Potassium hypophosphite. .. .gr. 64 Flavoring (any desired kind, see above) sufficient Water, to make fl.oz. 16 Agitate the emulsion with the flavor, then with 3 fluidounces of water con- taining the hypophosphites in solution, and finally with the balance of the water. Each fluidram contains 1 gr., Y\ gr. and Yz gr. respectively of each of the hypophosphites. Emulsion of Cod-Liver Oil with Lactophosphate of Calcium. I. Cod-liver oil av.oz. 8 Acacia, fine powder av.oz. 2 Calcium lactate gr. 256 Phosphoric acid (U. S. P., 85 per cent.) fl.oz. \V 2 Syrup of tolu fl.oz. 1 1 4 Flavoring (any desired kind, see above) sufficient Water to make fl.oz. 16 ns STANDARD FORMULARY OF Emulsify the oil with the acacia, and 3 fluidounces of water, and add the flavoring. Then dissolve the calcium lactate in I fluidounce of water with the aid of the phosphoric acid, add the solution gradually to the emulsified oil, then the syrup, and lastly enough water to make 16 fluidounces. Mix the whole thoroughly. This emulsion should be freshly pre- pared when wanted. — N. F. Each fluidram contains about 2>4 gr. of so-called "lactophosphate of cal- cium." II. Stronger emulsion of cod- liver oil fl.oz. 14 Oil of sassafras m. 15 Oil of wintergreen m. 15 Calcium lactate gr. 256 Phosphoric acid (U. S. P. or 85 per cent.) fl.dr. iy 2 Water, to make fl.oz. 16 Agitate the emulsion with the oils, then dissolve the calcium lactate in 1 fluidounce of water with the aid of the acid, add this solution to the emulsion, agitate again, add enough water to make 16 fluidounces, and agitate again. Emulsion of Cod-Liver Oil with Malt Extract. See Extract of Malt and its combina- tions. Emulsion of Cod-Liver Oil with Phosphate of Calcium. I. Cod-liver oil av.oz. 8 Acacia, fine powder av.oz. 2 Calcium nhosphate gr. 256 Syrup of tolu fl.dr. 13 Flavoring (any desired kind, see above) sufficient Water to make fl.oz. 16 Emulsify the oil with the acacia, and 3 fluidounces of water, and add the flavoring. Then triturate the calcium phosphate with the syrup and a portion of the remaining water, add the mix- ture gradually to the emulsified oil, and lastly, enough water to make 16 fluid- ounces. Mix the whole thoroughly. The mixture should be well shaken before use. Each fluidram contains 2 gr. of cal- cium phosphate. — N. F. II. Stronger emulsion of cod- liver oil fl.oz. 14 Oil of sassafras m. 15 Oil of wintergreen m. 15 Calcium phosphate gr. 256 Water, to make fl.oz. 16 Agitate the emulsion with the oils ; triturate the calcium phosphate to a smooth mixture with iy 2 fluidounces of water, add this to the emulsion, agitate again, add enough water to make 16 fluidounces, and mix well. Emulsion of Cod-Liver Oil with Phosphates of Calcium and Sodium. I. Cod-liver oil av.oz. 8 Acacia, fine powder av.oz. 2 Calcium phosphate ..-gr. I2"8 Sodium phosphate gr. 128 Syrup of tolu fl.dr. 13 Flavoring (any desired kind, see above) .sufficient Water, to make fl.oz. 16 Emulsify the oil with the acacia, and 3 fluidounces of water, and add the fla- voring. Then triturate the salts to a fine powder, incorporate with the syrup and a portion of the remaining water, and triturate with the emulsified oil. Finally, add enough water to make 16 fluidounces, and mix the whole thor- oughly together. Each fluidram contains 1 gr. each of the phosphates of calcium and sodium. II. Stronger emulsion of cod- liver oil fl.oz. 14 Oil of sassafras m. 15 Oil of wintergreen m. 15 Calcium phosphate gr. 128 Sodium phosphate gr. 128 Water, to make fl.oz. 16 Triturate the two phosphates with i l A fluidounces of water until well mixed. Add the oils to the emulsion, agitate well, add the aqueous mixture, again ag- itate, then add enough water to make 16 fluidounces, and again agitate thor- oughly. PHARMACEUTICAL PREPARATIONS. 119 Emulsion of Cod-Liver Oil with Phosphate of Sodium. Every 16 fluidounces should contain 128 gr. of sodium phosphate. This should be dissolved in 2 fluidounces of water which may be added to 14 fluid- ounces of either simple or stronger emulsion of cod-liver oil, or the solution may be incorporated during the process of emulsification in making an emulsion of cod-liver oil. Each fluidram contains 1 gr. of so- dium phosphate. Emulsion of Cod-Liver Oil, with Egg. Cod-liver oil fl.oz. 4 Glycerite of yolk of egg. . .av.oz. 1^4 Syrup of tolu fl.oz. V/ 2 Flavoring. Water, to make fl.oz. 16 To the glycerite contained in a suit- able bottle, gradually add the cod-liver oil, in small portions at a time, shaking after each addition, until the added por- tion is emulsified. Then gradually add the syrup of tolu and the flavoring, continuing the trituration. Finally add sufficient water. — N. F. This replaces the Emulsion Cod Liver Oil, Phosphatic, of the previous issue. Emulsion of Cod-Liver Oil, Phos- phorized. Cod-liver oil av.oz. 8 Acacia, powder av.oz. 2 Calcium hyphosphite gr. 128 Sodium hyphosphite gr. 128 Spirit of phosphorus fl.oz. 1 Simple syrup fl.oz. 1 Water, to make fl.oz. 16 Triturate the oil with the acacia until well mixed, add 3 fluidounces of water, all at once, until emulsification is com- pleted, then add 2 fluidounces of water in which the hypophosphites have been dissolved, then the spirit and syrup, and finally enough water to make 16 fluid- ounces, and stir the whole thoroughly together. Each fluidram contains 1 gr. each of the hypophosphites of calcium and so- dium and about 1/200 gr. of phosphorus. Emulsion of Cod-Liver Oil, Stronger. Prepare this like emulsion of cod- liver oil No. I or II, but adding only enough water to make 14 fluidounces of product. Instead of using formula No. I or II, Nos. Ill, IV, V, VII, VIII, IX, X, XI or XII may be used instead if thought more desirable, leaving out a portion of the water as before. This makes a stock emulsion to be used for preparing the usual 50 per cent, simple emulsion of cod-liver oil, or compound emulsions containing such ad- ditions as may be desired. It is advisable to keep this emulsion in the bottles in which the emulsions are usually dispensed, 7 fluidounces in an 8-ounce bottle, 14 fluidounces in a 16- ounce bottle, etc. Whenever an emul- sion of cod-liver oil, simple or com- pound, is wanted it can then, in many cases at least, be quickly prepared by simple addition of the requisite ingre- dients. The medicating agent, if liquid, may be added, the mixture agitated, enough water added to fill the bottle, and the whole again agitated. Or if the medicating liquid be solid, it may be dissolved, or, if insoluble, triturated with the water, the solution or mix- ture added to the emulsion, enough wa- ter added to fill the bottle, and the whole again well agitated. Emulsion of Cod-Liver Oil with "Wild Cherry. I. Cod-liver oil av.oz. 8 Acacia, fine powder av.oz. 2 Fluid extract of wild cherry.fl.oz. 1 Syrup of tolu fl.dr. 13 Flavoring (any desired kind, see above) sufficient Water, to make fl.oz. 16 Emulsify the oil with the acacia and 3 fluidounces of water, and add the fla- voring. Mix the fluid extract and syrup with a portion of the remaining water, and add the mixture gradually to the emulsified oil. Lastly, add enough water to make 16 fluidounces and mix the whole thoroughly.— N. F. 120 STANDARD FORMULARY OF II. Stronger emulsion of cod- liver oil fl.oz. 14 Oil of bitter almond drops 5 Fluid extract of wild cherry.fl.oz. 1 Simple syrup fl.oz. I Mix well by agitation. Emulsion of Linseed Oil, Dr. Thom- son's. Linseed oil fl-oz. 4 Oil of wintergreen fl.dr. y 2 Oil of cinnamon fl.dr. x / 2 Acacia, powder av.oz. 2 Water fl.oz. 6^ Glycerin fl.oz. V/* Simple syrup fl.oz. 3 Hydrocyanic acid, diluted m. 45 Triturate the mixed oils with the aca- cia, add 3 fluidounces of water, triturate until emulsified, add the syrup, glycerin, acid, and remainder of the syrup and mix well. Emulsion of Monobromated Cam- phor. Monobromated camphor ....gr. 36 Sweet almond oil fl.dr. 5 Acacia, powder gr. 135 Distilled water, to make. . .fl.oz. 4 Dissolve the camphor compound in the oil, add the gum, triturate well, add 4^2 fluidrams of water, triturate until an emulsion is formed, and then add enough water to make 16 fluidounces. — D. Emulsion of Paraffin Oil and Hypo- , phosphites. (Compound Emul- sion of Liquid Petrolatum. — Emulsion of Petroleum with Hypophosphites, Brit. Form.) This may be prepared acceptably ac- cording to either of the following meth- ods: I. Paraffin oil (liquid petrola- tum) fi.oz. $y 2 Acacia, powder av.oz. 2 l / 2 Glycerin fl.oz. iJ4 Calcium hypophosphite gr. 96 Sodium hypophosphite gr. 96 Water, to make fl.oz. 16 Add the acacia to the oil and mix thoroughly in a large mortar, then add 4 fluidounces of water, all at once, and triturate brisklv until the emulsion is formed. Dissolve the hypophosphites m 3 fluidounces of water, to which add the glycerin; then add this to the emulsion and rub well together, add water to make up 16 fluidounces, and triturate thoroughly. This contains about ZZ 1 A per cent, of paraffin oil and Y\ gr. of each of the hypophosphites. See also Emulsion of Petroleum, to which hypophosphites may be added if desired. II. Liquid petrolatum fl.oz. 4 Oil of sweet almond fl.oz. 2 Acacia, powder av.oz. i l / 2 Glycerin fl.oz. 1 Sodium hypophosphite gr. 128 Calcium hypophosphite gr. 128 Lime water fl.oz. 4 Water, to make fl.oz. 16 Mix all the oil and petrolatum and incorporate well with the gum, then add 2 l / 2 fluidounces of the water all at once, stir briskly until an emulsion is formed ; dissolve the hypophosphites in 3 fluid- ounces of the lime water, mix with the preceding liquid, then add the glycerin, and enough water to make 16 fluid- ounces. This contains 25 per cent, of liquid petrolatum and 1 gr. of each of the hypophosphites. These preparations may be flavored in any suitable manner. III. Liquid paraffin fl.oz. 5 Acacia, powder av.oz. 2 r / 2 Oil of cinnamon m. 15 Tragacanth, powder gr. 75 Calcium hypophosphite gr. 120 Sodium hypophosphite gr. 120 Distilled water, to make. . .fl.oz. 15 Mix the first four ingredients' thor- oughly in a mortar, add all at once 2>Va fluidounces of water, triturate until a perfect emulsion is produced, then add the hypophosphites dissolved in 2 l / 2 fluidounces of water, and finally add enough water to make 15 fluidounces. — Brit. Form. PHARMACEUTICAL PREPARATIONS. 121 Emulsion of Petroleum. White petrolatum gr. 360 Sweet almond oil fl.oz. 4j4 Acacia, fine powder oz. 2 Simple syrup fl.oz. 1^2 Tincture of lemon peel. . . .fl.dr. 2 Water, to make fl.oz. 16 Melt the petrolatum and mix it thor- oughly with the almond oil. Mix the acacia and tragacanth, in a capacious mortar, with 2Y2 fluidounces of water, and add the oil mixture gradually, trit- urating rapidly until a smooth emulsion is formed. To this add the syrup and tincture and the remainder of the water, and mix well. — N. F. See also Emulsion of Paraffin Oil with Hypophosphites for similar prep- arations. Emulsion, Phosphatic. See Emulsion of Cod-Liver Oil, Phos- phatic. Emulsion of Phosphorus. (Phos- phorated Emulsion.) Phosphorated oil m. 10 Olive oil m. 10 Acacia, powder gr. 60 Distilled water m. 90 Peppermint water fl.oz. 3^4 Simple syrup fl.dr. 3 Mix the oils and gum in a dry mor- tar, emulsify by addition of the water, then add the peppermint water and the syrup, and mix well.— D. Each fluidram represents about 1/300 gr. of phosphorus. The proportion of phosphorus in the product can be increased by using more of the phosphorated oil and correspond- ingly less of the olive oil. Emulsion of Pumpkin Seed. Eclectic : Pumpkin seed, fresh av.oz. 2 Water fl.oz. 7^ Beat the seeds in a mortar until the outer envelope is broken, then add 1 fluidounce of water and rub the mix- ture briskly; continue to beat and rub it, with occasional additions of small portions of water, until 7^ fluidounces have been added and the outer envelope is completely separated from the pulp, which is converted by the process into a smooth emulsion. Strain by passing through a wire sieve, rubbing the sep- arated envelopes to remove, as thor- oughly as possible, adherent portions of the pulp. This is used to expel tapeworm, giv- ing the above amount at night, allowing no supper and but a light diet during the day. The following morning a dose of castor oil should be given, to which 30 to 60 drops of ether may be added to make the treatment more certain. To the emulsion may be added sugar or milk, if desired, to make it more pala- table. Emulsion of Salicylic Acid. (Emul- sio Salicylica.) Salicylic acid gr. 40 Sweet almond oil fl.dr. 6 Acacia, powder gr. 160 Orange flower water fl.oz. 2^4 Simple syrup fl.dr. 3 Mix the salicylic acid and oil, add the gum, and to this mixture add 4 flu- idrams of orange flower water, stirring briskly until emulsification is complete ; then add the remainder of the water and the syrup. — D. This forms about a 2 per cent, emul- sion of salicylic acid, each fluidram con- taining about 1% gr. of salicylic acid. Emulsion of Spermaceti. An emulsion of spermaceti may be prepared as follows: Spermaceti gr. 64 Acacia, powder gr. 15 Water, warm fl.oz. 2> l A Simple syrup fl.oz. 24 Put the syrup and gum into a warm mortar, add the spermaceti and triturate with a warm pestle until well mixed ; then add the warm water gradually, and continue agitation or trituration until the whole is cold. Emulsion of Turpentine Oil. I. Oil of turpentine, rectified. fl.dr. 4^ Sweet almond oil fl.dr. iVz Simple syrup fl.oz. I Acacia, fine powder gr. 270 Water, to make fl.oz. 4 122 STANDARD FORMULARY OF Introduce the acacia into a perfectly dry bottle of sufficient capacity, add the two oils, shake the bottle thoroughly, then add 9 fluidrams of water, and in- corporate by vigorous shaking. When the oils have been completely emulsi- fied, first add the syrup, in several por- tions, shaking after each addition, and then enough water, in divided portions, shaking after each addition, to make the product measure 4 fluidounces.— U. S. P. This differs from the formula of the N. F. (No. II) and the two formulas illustrate different methods of making emulsions of volatile oils. It is consid- ered that the addition of a bland fixed oil to a volatile oil makes the emulsion more permanent. About 1 volume of fixed oil to 2 volumes of volatile oil will be sufficient II. Oil of turpentine fl.dr. 4 Acacia, fine powder gr. 36 Yolk of egg fl.dr. 5 Aromatic elixir fl.dr. 5 Cinnamon water, to make, .fl.oz. 4 Triturate the acacia with the yolk of egg, then add the oil very slowly, con- tinuing the trituration, and finally add the elixir and enough cinnamon water, in the same manner, to make 4 fluid- ounces. — N. F. (1st Edit.). For general formulas for making emulsions of volatile oils, see Emul- sions of Volatile Oils. Emulsion of Turpentine Oil, Strong- er. (Forbes' Emulsion of Oil of Turpentine.) Oil of turpentine fl.oz. 4 Acacia, fine powder gr. 90 Water fl.oz. 4 Pour the oil into a perfectly dry vial, having a capacity of a little more than 8 fluidounces, and shake so that the in- ner surface may be completely wetted by the oil. Then add the acacia, and shake again. Now add one-half of the water, and shake until the <^1 separates in form of a milky emulsion. Add the remainder of the water, and continue the shaking until the oil separates from the water in the form of a creamy emul- sion upon standing. This emulsion must be shaken before dispensing. The formula for this strong emulsion of oil of turpentine is essentially that proposed by Mr. J. W. Forbes, in 1872. While the oil separates in the form of a cream-like layer upon standing, the two liquids are easily united by brief sha- king. It keeps well, and is useful for dispensing small quantities of oil of tur- pentine in a fairly well emulsified con- dition. Emulsions of Volatile Oils. The present National Formulary states that although volatile oils are readily emulsionized by themselves, the addition of a small portion of some bland fixed oil, such as sweet almond oil, is an advantage. Usually about 1 volume of fixed oil will be enough for 2 volumes of the volatile oil as exem- plified in the following: Volatile oil gr. 150 Sweet almond oil gr. 90 Acacia, fine powder gr. 60 Simple syrup fl.dr. 6 Water, to make fl.oz. 3 Weigh the oils carefully into a mor- tar, add the acacia and triturate them thoroughly together; then add 90 gr. of water, carefully weighed, and triturate briskly until a creamy emulsion is pro- duced. To this add the syrup and enough water to make 3 fluidounces of emulsion. The former N. F. gave a different formula, which is worth mentioning: Volatile fl.dr. 4 Acacia, fine powder gr. no Simple syrup fl.oz. I Water, to make fl.oz. 4 Pour the oil into a perfectly dry bot- tle, and, having corked the latter, agitate it so that the inner surface will be com- pletely wetted by the oil; then add file acacia, and shake again; finally add the syrup and enough water to make 4 fluid- ounces, and mix thoroughly. This latter is the so-called "bottle method" of making emulsions. PHARMACEUTICAL PREPARATIONS 123 Still another method of making an emulsion of a volatile oil may be found under Emulsion of Turpentine Oil. - Emulsions of volatile oils (without fixed oil) made with acacia will sep- arate into aqueous and creamy layers, the former occupying but a small por- tion of the total volume. Tragacanth makes an emulsion which is liable to be so thick that it cannot be poured from the bottle. A better emulsion will be obtained if acacia and tragacanth be uni- ted as follows : Acacia, powder gr. 15 Tragacanth, powder gr. 15 Corn starch gr. 15 Volatile oil fl.dr. 4 Simple syrup fl.oz. 1 Water, to make fl.oz. 4 Prepare like the above "bottle meth- od" for emulsion of volatile oil, substi- tuting the three powders for the acacia. Emulsion of Wax. This may be prepared like the emul- sion of spermaceti, substituting yellow wax for the spermaceti, or by the use of the following method of D. : Yellow wax gr. 192 Mucilage of acacia fl.oz. l 1 /^ Distilled water, warm fl.oz. 2^ Melt the .wax in a capacious mortar on a water bath or by any other suitable method, at the same time warming the pestle; to the wax add the mucilage, mix well until an emulsion is formed, then add the distilled water. Enemas. (Clysters. — Rectal Injec- tions.) These are solutions or mixture in- tended for injection into the rectum. They are intended either for evacuation of the bowels, or for medicating or feeding purposes when the stomach will not retain medicine or food. The amount of liquid used as enema is large or small, depending on the purpose. The Brit. Pharm., 1885 and previous edi- tions, recognized several enemas, but none is official in the 1898 edition. Esprits. This is the French name for spirits, or alcoholic solutions oi volatile oils. Essences. (Essentia?.) Many of the spirits (see Spirits) are commonly known as "essences." Form- ulas for other so-called essences are given herewith. Essence of Diastase and Pancreatin (Disatasic Essence of Pancrea- tin.) The following makes a suitable prep- aration of this kind : Diastase (malt or taka) gr. 40 Pancreatin, pure gr. 40 Sodium bicarbonate gr. 15 Water fl.oz. 2 Sherry wine fl.oz. 2 Simple syrup fl.oz. 2 Aromatic elixir, to make. . .fl.oz. 16 Essence of Ginger, Soluble. (Solu- tion of Ginger. — Liquor Zingi- bers. — Soluble Tincture of Gin- ger.) Fluid extract of ginger (U. S. P.) fl.oz. 5 K Pumice, moderately fine powder av.oz. 1 % Water, to make fl.oz. 16 Pour the fluid extract into a bottle, add to it the pumice, and shake the mixture thoroughly and repeatedly in the course of several hours. Then add the water in portions of about 2 fluid- ounces, shaking well and frequently aft- er each addition. When all is added, repeat the agitation occasionally during 24 hours, then filter, returning the first portions of the filtrate until it runs through clear, and, if necessary, pass enough water through the filter to make 16 fluidounces. Essence of Life, Augsburg. Angelica root gr. 300 Myrrh gr. 240 Gentian gr. 240 Aloes, socotrine gr. 240 Rhubarb gr. 120 Zedoary gr. 120 Spanish saffron gr. 60 Camphor gr. 60 Castor gr. 60 Diluted alcohol fl.oz. 16 Reduce the drugs to moderately fine powder, add the liquid, macerate for 5 days, agitating frequently, then express, and filter. This is very similar to the Elixir oi Long Life, which see. '124 STANDARD FORMULARY OF Essence of Pepsin and Rennin Comp. I. Pepsin, scale (1 :3000) . . . . . .gr. 338 Rennin gr. 240 Lactic acid, 75 per cent m. 30 Tinct. of sweet orange peel. fl. dr. 2y 2 Alcohol fl.oz. 7 Glycerin fl.oz. 5 Oil of nutmeg m. 6 Purified talc gr. 300 Water, to make fl.oz. 32 Mix the pepsin and rennin with 10 fluidounces of water, add the acid and glycerin, allow the mixture to stand with occasional gentle agitation until solution is effected, add the tincture, oil and alco- hol, previously mixed, the latter being added in portions with agitation, and finally add sufficient distilled water to make the product measure 32 fluid ounces. Add the talc, allow to stand, shaking occasionally, and filter. Rennin is a milk-curdling enzyme pre- pared from calves' rennets. The following are among the best of other numerous formulas for this prep- aration which are in vogue: II. Pepsin, scale (1:3000) gr. 128 Hydrochloric acid, diluted.drops 10 Aromatic elixir fl.oz. 3 Glycerin fl.oz. 1 Water fl.oz. 6 Angelica wine, to make. . . .fl.oz. 16 Mix all, agitate frequently until the pepsin is dissolved, and filter through purified talcum. III. Pepsin, scale (1:3000) gr. 240 Hydrochloric acid, diluted. .fl.dr. 1 Glycerin fl.oz. 1 Comp. elixir of taraxacum.fl.oz. 1 Simple syrup fl.oz. 2 Alcohol fl.oz. 2 Oil of clove drop 1 Water, to make fl.oz. 16 Mix the pepsin, glycerin, acid and 8 fluidounces of water, agitate frequently until the pepsin is dissolved, then add the syrup, elixir, oil of clove first dis- solved in the alcohol, and the remainder of the water, and filter. IV. Pepsin, scale (1:3000) gr. 128 Glycerin fl.oz. 3^2 Oil of cinnamon drop 1 Oil of pimento drop 1 Oil of clove drops 2 Hydrochloric acid m. 20 Purified talcum av.oz. V/\ Alcohol fl.dr. 4 Sherry wine (good, and light color) fl.oz. 3^2 Distilled water, to make. . .fl.oz. 16 Mix the wine with the acid and 6 fluidounces of water; add to it the pep- sin and shake until dissolved; the oils are added to the alcohol, triturated with the talc, the pepsin solution gradually added and filtered ; return the first por- tions until the filtrate is perfectly bright, and pass the remainder of water through filter ; when every portion has passed, add the glycerin to the filtrate. V. Beringer's formula : Fresh calves' rennet av.oz. 3^ Glycerin fl.oz. 2> l A Alcohol .fl.dr. 14 Tinct. of sweet orange peel. .fl.dr. i l / 2 Water fl.oz. n]/ A Purified talcum av.oz. 1 Mix the rennet and glycerin, then add the alcohol, water and tincture of or- ange, and macerate for 4 or 5 days, with repeated agitation; add the talc, agitate and allow to stand for an hour, or until the talc has been largely de- posited ; now decant, on a muslin or flannel filter, the supernatant liquid first, and finally the dregs ; then filter through paper. Essence of Tamarinds. This is the formula adopted by the Berlin Apothecaries' Society: Tamarind pulp, purified. . .av.oz. 8^4 Alexandria senna (previous- ly extracted with alcohol) av.oz. ~\% Water, boiling fl.oz. 40 Infuse for 12 hours, then strain, press the marc, and evaporate the strained liquor by boiling to 19 av. ounces. Then take wYd, fluidounces of the residue, neutralize with solution of soda, and add: Alcohol fl.oz. s l / 2 Simple syrup fl.oz. \ X A Tincture of vanilla fl.dr. i$4 PHARMACEUTICAL PREPARATIONS. 125 Etheroles. These are a class of French prepara- tions similar to the ethereal tinctures used to some extent in this country. Extracts. (Solid Extracts.) These are solid or semi-solid prepara- tions, generally made by exhausting a drug, usually in a more or less fine powder, with a suitable menstruum, then evaporating the liquid obtained either to dryness or to pilular consistence. The process of the U. S. P. for the majority of its extracts is about as fol- lows : Moisten i av.pound of drug with 6^4 fluidounces of menstruum, pack it firmly in a cylindrical percolator, prefer- ably of glass, and add enough men- struum to saturate the drug and leave a stratum of liquid above it. When the liquid begins to drop from the percola- tor, close the lower orifice, and having closely covered the percolator, macerate for 48 hours. Then allow percolation to proceed (the rate of flow should be from 2 to 5 drops a minute), gradually adding more menstruum until 46 fluid- ounces of percolate are obtained or the drug is exhausted. Reserve the first 14^4 fluidounces of percolate, evaporate the remainder in a porcelain capsule at a temperature, usually, about 50 or 70 deg. G, to i l / 2 fluidounces, add the reserved portion, and evaporate the liquid at or below the above-mentioned temperature either to pilular consistence or to dryness. While the above process is a typical one for many extracts, the U. S. P. has many deviations from it. In many cases, the fluid extract is used to make the extract, thereby avoiding the preliminary extraction of the drug. The U. S. P. directs that the drug may be extracted by the process of re- percolation or any other process that will exhaust the drug. (See Extracts, Fluid.) About one-half of the extracts of the U. S. P. are evaporated to pilular con- sistence, the other half to dryness. To the pilular extracts, the U. S. P. 1890 directed the addition of 10 per cent, by weight of glycerin while still warm to keep them in a permanently plastic con- dition. The U. S. P. 1880 directed but 5 per cent., which is probably quite suf- ficient. The present U. S. P. directs 10 p. c. in the preliminary portion of the book, but does not direct its use in only one of the formulas, viz., licorice, when 5 p. c. is specified. Many of the dry extracts of the U. S. P. are directed to be reduced to fine powder and enough powdered peeled Russian licorice root added to establish a definite relationship between the fin- ished extract and the drug. In the pre- liminary portion of the U. S. P., it is stated that dried and powdered marc of the same drug may be used for this pur- pose. ' Anew feature of the present U. S. P. is that many extracts are to be assayed. According to the Germ. Pharm^ the drug is to be extracted according to the method adapted to each case and the liquid is to be evaporated to extract consistency. Alcoholic liquids are to be evaporated at a temperature not exceed- ing 85 deg. C, ethereal liquids at a tem- perature not above 35 deg. C. When alcohol has been used in the menstruum, small amounts of alcohol should be add- ed towards the end of the evaporation and the liquid stirred constantly. Ex- tracts are either to be of the consistency of fresh honey, thick so that when cold they cannot be poured from the vessel, or dry when they may be rubbed to powder. Dry extracts are to be pre- pared by evaporating the liquid in a porcelain vessel on a steam or water bath to tough consistency, while warm removed from the dish, pulled into strings, and then dried at a gentle heat. Dry narcotic extracts are to be pre- pared from the thick extracts by mixing 4 parts of the latter with 3 parts of fine- ly-powdered licorice root, mixed thor- oughly in a porcelain evaporating dishj 126 STANDARD FORMULARY OF heated on a water bath until there is no further loss in weight, then rubbed to nowder while still warm and enough finely-powdered licorice root added to make twice the weight of the extract originally employed. Extracts, Fluid. (Called Fluidex- tracts by the U. S. P., 9th Re- vision.) These are preparations which, accord- ing to the U. S. P. and N. F., represent ioo grams of drug in every ico cubic centimeters of liquid, or, in other terms, i pint (16 fluidounces) of fluid extract contain the virtues of i6^4 av. ounces of drug. There are a number of processes for making these preparations, all of them being more or less satisfactory, but all having some disadvantageous features. The process directed by the U. S. P. is known as "maceration and percolation" or as "simple percolation." The follow- ing is the general process, the kind of menstruum, and the quantity of perco- late to be set aside as reserve being specified in each case: i6}i av.ounces of drug in No. 6o pow- der are thoroughly moistened with 6^ fluidounces of menstruum, packed firm- ly in a cylindrical percolator, preferably of glass, and enough menstruum is poured on to completely saturate the powder and leave a stratum of liquid above it. When the liquid begins to drop from the percolator, close the low- er orifice, and having closely covered the percolator to prevent evaporation, mac- erate for 48 hours. Then allow perco- lation to proceed slowly, gradually add- ing menstruum until the drug is ex- hausted. Reserve the first n}4 to 14^/2 fluidounces of percolate and evaporate the remainder of the percolate at a tem- perature not exceeding 50 deg. C. to soft extract, dissolve this in the reserved portion, and add enough menstruum to make 16 fluidounces of product, if the menstruum in the course of making the fluid extract be changed, the second menstruum is the one added at the end to make up the volume of 16 fluid- ounces. The evaporation of the weak percolate may be conducted in a still so as to recover the larger portion of the alcohol contained therein, then the evap- oration may be completed in a porcelain capsule on a water bath at not above the specified temperature. The U. S. P. also permits the use of the process of repercolation whenever practicable. The fluid extracts of the N. F. are to be prepared according to one of the fol- lowing two processes, the particular one to be employed being designated in each case. These two processes are neces- sary because, in the preparation of some fluid extracts, two menstrua are suc- cessively used, the first containing glyc- erin, and being in definite proportion to the drug used, while the second is free from glycerin, being intended for the exhaustion of the drug and subsequent evaporation. Accordingly these men- strua are designated as menstruum I (containing glycerin) and menstruum II (containing no glycerin). As an alter- native to either of these processes, a third process, termed fractional perco- lation, may be used. In this the use of heat is avoided, and it involves the use of only one kind of menstruum, even in the case of drugs for which two dif- ferent menstrua (I and II) are pre- scribed. In the case of the latter, a sufficient quantity of menstruum I must be prepared to serve throughout the process. Process A. The Menstruum contains no Glycerin. This is practically the same as the U. S. P. process, 14 fluidounces of percolate to be reserved for 16^ av. ounces of drug, and the second percolate to be evaporated at a temperature sufficiently low to prevent loss of any important volatile constituent (the temperature di- rected by the U. S. P. should be pre- ferred), the soft extract to be dissolved in enough menstruum so that when add- ed to the reserve portion, the total will PHARMACEUTICAL PREPARATIONS. 127 measure 16 fluidounces. Allow the prod- uct to stand a few days, or longer, if convenient, and filter, if necessary. Process B. The Menstruum contains Glycerin. Moisten 16Y4. av. ounces of the drug with a sufficient quantity of mentsruum I to render it distinctly damp and to maintain it so after several hours' mac- eration in a well-covered vessel. When the drug has ceased to swell, pack it in a suitable percolator and pour the re- mainder of menstruum I on top. When this has just disappeared from the sur- face, follow it by a sufficient quantity of menstruum II. As soon as the perco- late begins to drop from the orifice, close the latter, cover the percolator, and allow the contents to macerate dur- ing 24 (or better 48) hours. Then per- mit the percolation to proceed. Receive the first 13V2 fluidounces of the perco- late separately and set it aside. Then continue the percolation with men- struum II, until the drug is practically exhausted. Evaporate this second por- tion — at a temperature sufficiently low to prevent the loss of any important volatile constituent — to a soft extract, and dissolve this in a sufficient quantity of menstruum II, so that when this is added to the reserved portion, the prod- uct will measure 16 fluidounces. Allow the fluid extract to stand a few days, or longer, if convenient, and filter, if nec- essary. Process C. Fractional Percolation. Take of the drug, in powder of the prescribed fineness, i6^4 av. ounces and divide it into three portions of 8 l / 2 , S/i and 3 av. ounces. Moisten the first portion of the drug (8H av. ounces) with the menstruum and percolate in the usual manner. Set aside the first 3 fluidounces of perco- late, and continue until 24 fluidounces more of percolate have passed, which must be received in several portions, so that the more concentrated will be sep- arate from the last, weak percolate. Then moisten the second portion of the drug (5*4 av. ounces) with the more concentrated percolates received during the preceding operation after the first 3 fluidounces have passed, and percolate again in the usual manner, using the several reserved percolates, successively, as menstrua. Set aside the first 5 fluid- ounces and continue the percolation un- til 10 fluidounces more have passed, which should also be received in sev- eral portions. Finally moisten the third portion of the drug (3 av. ounces) with the most concentrated of the last reserved perco- lates, and proceed as directed for the second portion. Collect 8 fluidounces of percolate, and mix with the two por- tions (5 and 3 fluidounces) previously set aside, so as to make 16 fluidounces of fluid extract. Note. — If this method is applied to drugs for which the Process B is di- rected, use a sufficient quantity of menstruum I to obtain the required quantities of percolate, and omit the use of menstruum II. Manufacturing firms employ still other processes besides those described above. The liquid extracts of the Brit. Pharm. are usually, though not in all instances, of the same strength as the fluid extracts of the U. S. P. and N. F. and are made by processes similar to those used in the latter. According to the Germ. Pharm., fluid extracts are made by percolation, 100 parts by weight of product being made from 100 parts by weight of drug. The rate of flow of liquid is not to exceed more than 40 drops per minute. The first 85 parts by weight of percolate are to be reserved, percolation is to be con- tinued until the drug is exhausted, this weak percolate is to be evaporated at a temperature which will avoid loss ot active volatile constituents to thin ex- tract, and then dissolved in enough menstruum to make 15 parts which is to be added to the reserved percolate. 128 STANDARD FORMULARY OF Extract of Aconite. Make according to the general process given under Extracts, which see, using alcohol as a menstruum, the drug being the root of aconite. The extract should be of pilular consistence. — N. F. Appen- dix and U. S. P. 1890. Extract, Fluid, of Aconite. Prepare according to the general proc- ess (see Extracts, Fluid) from the root, reserving 1234 fluidounces as the first percolate (for 16^. av. ounces of drug) and using as menstruum a mixture of 3 volumes of alcohol and 1 of water. The remainder of the percolate is to be evaporated, in a porcelain dish, at a temperature not exceeding 50 deg. C, to soft extract ; dissolve this in the re- served portion and mix thoroughly. The product is to be assayed and made to contain 0.4 gram of aconitine in each 100 cc. If it contains more than this, enough menstruum is to be added to reduce it to this standard. — U. S. P. Extract of Aconite Leaves. Aconite leaves av.oz. 16 Alcohol fl.oz. 19 Diluted alcohol sufficient Mix the drug with 6 fluidounces of alcohol, put into a percolator, add the remainder of the alcohol, then percolate with diluted alcohol to 20 fluidounces, and allow this percolate to evaporate spontaneously to 3^2 fluidounces. Con- tinue the percolation with diluted alco- hol to get 40 fluidounces more of per- colate or until the drug is exhausted. Evaporate this on a water bath, at not above 72 deg. C. to the consistence of syrup, add the other 2V2 fluidounces, and then continue evaporation at not above 50 deg. C. to proper consistence. — U. S. P. 1870. Extract, Fluid, of Adonis. (Fluid Extract of Bird's Eye or False Hellabore.) From the root of Adonis vernalis. Prepare according to Process A (see Extracts, Fluid), using the drug in No. 60 powder and alcohol as the mens- truum. — X. F. Extract of Aloes. Aloes av.oz. 5 Water, boiling fl.oz. 48 Mix the aloes with the water in a suitable vessel, stirring constantly until the particles of aloes are thoroughly disintegrated, let the mixture stand for 12 hours, pour off the clear liquid, strain the residue, mix the liquids, and evap- orate to dryness by means of a water or steam bath. The Brit. Pharm. recognizes an ex- tract of barbadoes aloes which is to be prepared like the above, but the evapora- tion is to be conducted at a temperature not above 60 deg. C. The extract of aloes of the Germ. Pharm. is made by dissolving 8 av. ounces of cape aloes in 38 fluidounces of boiling water, then adding another 38 fluidounces of water, setting aside for 2 days, decanting the liquid from the deposited resin, filtering the former and evaporating the filtrate to dryness. Extract, Fluid, of Aloes. What is commonly sold under this name is usually made by dissolving 8 av. ounces of aloes in 16 fluidounces of diluted alcohol by the aid of a moderate heat, straining, and evaporating the colature to 16 fluidounces. To make the official tincture of aloes, it is directed to mix 3 fluidounces of the above with 3 fluidounces of fluid extract of licorice and 10 fluidounces of diluted alcohol. Extract, Fluid, of Aloes and Myrrh. This, like the fluid extract of aloes, is one of the "convenience" prepara- tions put up by the large manufacturers. It may be prepared as follows : Socotrine aloes av.oz. 4V2 Myrrh av.oz. 4*/> Alcohol sufficient Mix the drugs is coarse powder with 12 fluidounces of alcohol, macerate for 7 days in a warm place, occasionally agitating, then heat moderately on a water bath for 2 hours, strain through flannel, add through the strainer enough PHARMACEUTICAL PREPARATIONS. 129 alcohol to make 16 fluidounces, and al- low to cool. To make the tincture of aloes and myrrh, the manufacturers direct that 5 fluidounces of this "fluid extract" be mixed with 11 fluidounces of alcohol. Inasmuch as the official preparation con- tains licorice, the tincture is not properly made unless i J A fluidounces of the alco- hol be replaced by fluid extract of licorice. Extract, Fluid, of Asafetida, Ethe- real. Asafetida, broken into small pieces av.oz. 1 Stronger ether fl.oz. 3^ Water fl.dr. 3 Mix all in a well-stoppered bottle, macerate for 2 or 3 days, agitating oc- casionally, and strain. — Eclectic. Extract, Fluid, of Australian Fever Bark. (Fluid Extract of Alsto- nia Constricta.) Extract the bark in moderately fine powder by the use of alcohol as a menstruum, using the process of the U. S. P. or N. F., or any other suitable process of making fluid extracts. Extract, Fluid, of Angelica Boot. Prepare according to Process A (see Extracts, Fluid), using the drug in No. 60 powder, and as menstruum a mixture of 3 volumes of alcohol with 2 of water. — N. F. Extract of Apples, Ferrated. (Ex- tractum Ferri Pomatum. — Ex- tractum Pomi Ferratum. — Crude Malate of Iron.) Iron, in the form of fine, bright wire, and cut gr. 140 Ripe sour apples av.oz. 16 Water sufficient Convert the sour apples into a homo- geneous pulp by pounding or grinding, and express the liquid portion. Then mix the latter with the iron in an enameled or porcelain vessel, macerate for 48 hours, and then apply the heat of a water bath, until no more bubbles of gas are given off, adding a little water from time to time to make up any loss by evaporation. Dilute the liquid with water to make it weigh 16 av. ounces and set it aside for a few days. Then filter, and evaporate the filtrate in the before-mentioned vessel to a thick extract, which should be greenish-black, and should yield a clear solution with water. This preparation contains about 6 per cent, of iron, calculated as metal. — N. F. and Germ. Pharm. Extract, Fluid, of Arnica Flowers. Prepare according to Process A (see Extracts, Fluid), using the drug in No. 40 powder, and diluted alcohol as the menstruum. — N. F. Extract of Arnica Root. Make according to the general process given under Extracts, which see, the menstruum being diluted alcohol, and obtaining an extract of pilular consist- ence. — N. F. Appendix and U. S. P. 1890. Extract, Fluid, of Arnica Root. Prepare according to the general process (see Extracts, Fluid), using as a menstruum a mixture of 3 volumes of alcohol and 1 of water. — U. S. P. 1890. Extract, Fluid, Aromatic. Prepare from aromatic powder ac- cording to the general process (see Ex- tracts, Fluid), using alcohol as a mens- truum, moistening 16^4 av. ounces of drug with s l A fluidounces of menstruum and reserving 13^2 fluidounces as the first percolate. The remainder of the percolate is to be evaporated at a tem- perature not above 50 deg. C. — U. S. P. Extract, Fluid, of Bamboo Brier, Compound. (Alterative Com- pound. — McDade's Compound. — Creek Indian Remedy. — Mistura Smilacis Compositus.) Bamboo brier root av.oz. 4 Stillingia av.oz. 4 Burdock root av.oz. 4 Poke root av.oz. 4 Prickly ash bark av.oz. 1 Diluted alcohol sufficient Mix the drugs, reduce to fine powder, and extract, using diluted alcohol as a menstruum, by the process of the U. S. P. or N. F., or any other suitable proc- 130 STANDARD FORMULARY OF ess for fluid extracts, the product to measure 16 fluidounces. Extract, Fluid, of Baptisia. Baptisia in No. 30 powder. Prepare according to Process A (see Extracts, Fluid), using the drug in No. ■60 powder, and a mixture of 3 volumes of alcohol and 1 of water as a mens- truum. — N. F. Extract, Fluid, of Bearsfoot. (Fluid Extract of Polymnia.) Extract the root in moderately fine powder by any suitable process for fluid extracts, using alcohol as the menstruum. Extract of Belladonna. Sprinkle 16 av. ounces of fresh bella- donna herb in blossom with 6 fluidrams of water, contuse and express. Moisten the residue with 18 fluidrams of water, contuse again, and express. Mix the two liquids, heat on a water bath to 8o deg. C, strain, evaporate on a water bath to iH av. ounces, and add 2 fluid- ounces of alcohol. Allow to stand for 24 hours, agitating frequently, strain, mix the residue with 6 fluidrams of al- cohol and 2 of water, warm this for a short time, in a closed vessel, agitating repeatedly, allow to stand, decant the clear liquid; add it to the first alcoholic liquid, filter, and evaporate the filtrate on a water bath to thick extract.— Germ. Pharm. For U. S. P. extract of belladonna, see extract of belladonna leaves. Extract of Belladonna, Alcoholic. (Extract of Belladonna Root.) Evaporate one fluidounce of liquid extract of belladonna (see Extract, Fluid, of Belladonna) in a tared porce- lain capsule, on a water bath, to the consistence of a moderately firm ex- tract, and weigh. Substract the weight, in grains, of the extract obtaine'd from 3^0 grains ; the difference indicates the amount of milk sugar to be used as a d^uent for each fluidounce of liquid ex- tract to make the extract. Now evaporate 8 fluidounces of the liquid extract to a thin syrup, add to it the requisite quantity of milk sugar as determined from the data obtained from the foregoing experiment, and continue the evaporation until the ex- tract weighs 6*4 av. ounces. — Brit. Pharm. The extract of the Brit. Pharm. 1885 contained no milk sugar and average samples of it were about the strength of the extract of the present Brit. Pharm. Extract of Belladonna, Green. Bruise the fresh leaves and young branches in a mortar (stone, marble or wedgewood, not metal), press out the juice and heat it to 55 deg. C. Separate the green coloring matter by straining through cloth, heat the strained liquid to 95 deg. C.j and filter. Evaporate the filtrate on a water bath to the consist- ence of thin syrup ; add to this the green coloring previously separated and passed through a hair sieve, stir the whole well together, and evaporate at a temperature not exceeding 55 deg. C. to the consistence of soft extract. At a temperature of 55 deg. C, the chlorophyll is coagulated ; at 95 deg. C. the albumen is coagulated. The latter is filtered out and rejected; the former is reincorporated with the extract, and the product will be bright green in color. Towards the end of the evapora- tion, the extract must be stirred con- stantly and vigorously so that the chlor- ophyll will be in intimate mixture with the extract. — Brit. Pharm. The above may be used as a general process for making the so-called "green" or "English extracts." For the extract of belladonna, Germ. Pharm., also made from fresh herb, see Extract of Belladonna. Extract of Belladonna Leaves. I. Make according to the general process for extracts (see Extracts), us- ing a mixture of 2 volumes of alcohol and 1 of water as a menstruum. Con- duct the evaporation at a temperature not to exceed 50 deg. C. — U. S. P. PHARMACEUTICAL PREPARATIONS. 131 The product is to be assayed and is to contain 1.4 per cent, of mydriatic alkaloids. If found to contain more than this percentage, enough powdered sugar of milk should be added to reduce it to the standard of 1.4 per cent. The Brit. Pharm. recognizes a green extract of belladonna (leaves) and an alcoholic extract of belladonna (root), which see. The Brit. Form, recognizes an extract of belladonna leaf; see No. II: See also Extract of Belladonna. II. Extract belladonna leaf in No. 60 powder with 90 per cent alcohol by percolation until exhausted, distil off most of the alcohol from the perco- late, and evaporate the residue on a water bath to the consistence of an ex- tract. — Brit. Form. This extract is to be assayed. Extract, Fluid, of Belladonna Root. (Fluid Extract of Belladonna U. S. P. 1880.) Prepare according to the general proc- ess (see Extracts, Fluid), moistening i6}% av. ounces of drug with s J A fluid- ounces of menstruum and collecting the first 12^4 fluidounces of percolate as the reserve. The menstruum is a mixture of 4 volumes of alcohol and 1 of water. The second percolate is to be evaporated at not above 50 deg. C. to soft extract and dissolved in the reserved percolate. The product is to be assayed and made to contain 14 gram of mydriatic alka- loids in 100 cc. If it contains more, enough menstruum should be added to reduce it to this standard. — U.-S. P. The liquid extract of belladonna of the Brit. Pharm. is made by extracting belladonna root in No. 20 powder by repercolation with a mixture of 7 vol- umes of alcohol and 1 of water, and standardizing the product so that every no minims of liquid extract contains 24 gr. of alkaloids (or 100 cc. contain 0.75 gm.). 9 Extract, Fluid, of Benzoin. (Con- centrated Tincture of Benzoin.) Benzoin, coarse powder. .. .av.oz. Sy 2 Alcohol sufficient Mix the benzoin with 12 fluidounces of alcohol, macerate the mixture in a warm place, then heat on a water bath until quite warm, strain through flan- nel, and wash the dregs and strainer with enough alcohol to make the cola- ture measure 16 fluidounces. This is similar to the "convenience" preparations put up by manufacturers. The tincture is directed to be prepared from it by mixing 6 fluidounces of it with 10 fluidounces of alcohol. It may be used for making benzoinated lard and for benzoinating other fats and fatty bodies. Extract, Fluid, of Benzoin, Com- pound. Benzoin av.oz. 4^2 Storax av.oz. 3 Tolu balsam av.oz. i J / 2 Aloes gr. 325 Alcohol sufficient Reduce the benzoin and aloes to coarse powder, add these and the tolu and storax to 12 fluidounces of alcohol contained in a closed vessel, digest the mixture, at a temperature not exceed- ing 65 deg. C, for 2 hours, then strain through flannel, and wash the residue and strainer with enough alcohol to make the colature measure 16 fluid- ounces. This is another "convenience" prep- aration from which the compound tinc- ture of benzoin is directed to be pre- pared by mixing 6 fluidounces with 10 fluidounces of alcohol. Extract, Fluid, of Berberis. (Fluid Extract of Berberis Aquifolium or Oregon Grape.) Prepare according to the general process (see Extracts, Fluid), using di- luted alcohol as the menstruum. Re- serve the first n J A fluidounces of perco- late (for every 16^4 av. ounces of drug used).— N. F. 132 STANDARD FORMULARY OF Extract, Fluid, of Bethroot. (Fluid Extract of Trillium.) From the rhizome of Trillium erec- tum and other species of Trillium. Prepare according to Process A (see Extracts, Fluid), using the drug in No. 40 powder, and a mixture of 3 volumes of alcohol and 2 of water as the mens- truum. — N. F. Extract of Bittersweet. (Extract of Dulcamara.) Dulcamara, coarse powder. av.oz. 4 Distilled water fl.oz. 24 Mix the drug with 16 fluidounces of water, macerate for 24 hours, strain with expression, upon the residue pour 8 fluidounces of boiling distilled water, macerate for 1 hour, and strain and ex- press once more. Mix the two cola- tures, add 2 drams or so of filter paper torn into shreds — scraps of filter paper from the cutting of filter papers may be used — and heat the liquid to boiling. Now skim the liquid, filter it through flannel, and evaporate to extract con- sistency. A preparation that will keep better may be prepared by evaporating the strained liquid after boiling to a weight of 2 av. ounces, adding to the latter 2 fluidounces of alcohol, mixing well, al- lowing to stand for 48 hours, filtering, passing through the residue on the filter a mixture of 6 fluidrams of alcohol and 2 of water, and evaporating the total filtrate to extract consistency. — D. modi- fied. The alcohol separates the mucilage extracted from the drug. Extract, Fluid, of Bittersweet. (Fluid Extract of Dulcamara.) Prepare according to the general process (see Extracts, Fluid). The menstruum is diluted alcohol— N. F. Appendix and U. S. P. 1890. Extract, Fluid, of Blackberry Root, (.fluid Extract of Rubus.) Prepare according to the general process (see Extracts, Fluid), by moistening i<5$4 av. ounces of it with S l/ 2 fluidounces of menstruum, reserving the first 12^4 fluidounces of percolate, and evaporating the remainder on a water bath. The menstruum is diluted alcohol. Extract, Fluid, of Blackberry Root Bark, Compound. Blackberry root bark av.oz. 12 Cinnamon av.oz. i]/ 2 Nutmeg av.oz. 1 1 / 2 Clove av.oz. 34 Pimento av.oz. £4 Diluted alcohol sufficient Mix the drugs, grind to fine powder, and extract, using diluted alcohol as a menstruum, by the process of the U. S. P. or N. F., or any other suitable proc- ess for fluid extracts, the product to measure 16 fluidounces. Other spices may be used instead of those in the amove formula. Such a preparation may be employed for making mild and pleasant carmina- tive elixirs, syrups, "balsams," etc., for summer complaint, dysentery, etc. The above may be converted into the aro- matic syrup of blackberry, N. F., by mixing 1 fluidounce with 5 of diluted alcohol, 11 fluidounces of blackberry juice, and 16 av. ounces of sugar, agi- tating until dissolved and straining. A syrup without juice may be prepared by mixing 1 fluidounce of fluid extract, 5 of diluted alcohol and 20 of simple syrup. Extract of Black Cohosh. (Extract of Cimicifuga.) Evaporate 4 fluidounces of the fluid extract in a porcelain dish by means of a water bath, at a temperature not ex- ceeding 70 deg. C, with constant stir- ring, to complete dryness. Reduce the product to fine powder and add enough peeled Russian licorice root in No. 80 powder to make the finished extract weigh 1 av. ounce. — U. S. P. Extract, Fluid, of Black Cohosh. (Fluid Extract of Cimicifuga, or Actaea Racemosa.) Prepare according to the general process (see Extracts, Fluid), by moistening i6}£ av. ounces of drug with 4 fluidounces, reserving the first 14^ PHARMACEUTICAL PREPARATIONS. 133 fluidounces of percolate, and evaporat- ing the second percolate on a water bath. The menstruum is alcohol. — U. S. P. The liquid extract of black cohosh of the Brit. Pharm. is made with the same menstruum. Extract, Fluid, of Bla^x Cohosh, Compound. Black cohosh av.oz. 8^4 Wild cherry av.oz. 4^ Licorice av.oz. 2^4 Ipecac ... av.oz. 1 Senega . . . av.oz. 1 Diluted alcohol sufficient Mix the drugs, reduce to fine pow- der, and extract, using diluted alcohol as a menstruum, by the process of the U. S. P. or N. F., or any other suitable process for fluid extracts, the product to measure 16 fluidounces. Extract, Fluid, of Black Haw. (Fluid Extract of Viburnum Prunifo- lium. — Fluid Extract of Vibur- num, U. S. P. 1880.) Prepare according to the general process (see Extracts, Fluid), but re- serving the first 13^ fluidounces of per- colate from i6}i av. ounces of drug. The menstruum is a mixture of 2 vol- umes of alcohol and 1 of water. — U. S. P. Extract of Bladder-Wrack. (Ex- tract Sea-Wrack, Fucus or Fu- cus Vesiculosus.) Exhaust the drug in No. 20 powder by percolation, using diluted alcohol as the menstruum. Recover the alcohol from the percolate by distillation and evaporate the residue to the consistence of a firm extract. — Brit. Form. Extract, Fluid, of Bladder-Wrack. (Fluid or Liquid Extract of Sea- Wrack, Fucus or Fucus Vesicu- losus.) I. Prepare according to Process A (see Extracts, Fluid), using the drug ~in No. 40 powder, and a mixture of 3 volumes of alcohol and 1 of water as the menstruum. — N. F. 21. Extract of bladder-wrack. av.oz. 2>Va Diluted alcohol, to make. . . .fl.oz. 16 Dissolve the extract in 13 fluidounces of diluted alcohol, let stand for an hour, filter, and wash the residue on the filter with the remainder of the diluted alcohol. — Brit. Form. Extract of Blessed Thistle. (Ex- tract of Carduus Benedictus.) Blessed thistle, cut av.oz. 8 Water, boiling fl.oz. 61 Pour on the drug 38 fluidounces of boiling water, let stand for 6 hours at 35 to 40 deg. C, agitate occasionally, express, add the remainder of the water to the residue, macerate again for 3 hours, again express, mix the two liquids, evaporate till it weighs 15 av. ounces, when cold add S J / 2 fluidounces of alcohol, set aside in a cool place for 2 days, filter, and evaporate the filtrate to thick extract. — Germ. Pharm. Extract, Fluid of Blood Root. (Fluid Extract of Sang-uinaria.) Prepare according to the general proc- ess (see Extracts, Fluid), moistening 16^4 av. ounces of the drug with 5 fluidounces of menstruum and reserving the first 13^2 fluidounces of percolate. The menstruum is a mixture of 11 vol- umes of 36 per cent, acetic acid and 25 volumes of water. — N. F. In the U. S. P. 1890, the preparation was made with a mixture of 3 volumes of alcohol and 1 of water. Extract, Fluid, of Blue Cohosh. (Fluid Extract of Caulophyl- lum.) Prepare according to Process A (see Extracts, Fluid), using the drug in No. 60 powder, and a mixture of '3 volumes of alcohol and 1 of water as the mens- truum. — N. F. Extract of Blue Flag. (Extract of Iris.) Prepare according to the general proc- ess (see Extracts), using alcohol as a menstruum, and obtaining an extract of pilular consistence. Extract, Fluid, of Blue Flag. (Fluid Extract of Iris.) Prepare according to the general proc- ess (see Extracts, Fluid). The mens- 134 STANDARD FORMULARY OF truum is alcohol. Extract, Fluid, of Boldo. From the leaves of Peumus Boldus. Prepare according to Process A (see Extracts, Fluid), using the drug in No. 60 powder, and a mixture of 2 volumes of alcohol and 1 of water as a mens- truum. — N. F. Extract, Fluid, of Boneset. (Fluid Extract of Thoroughwort or Eu- patorium.) Prepare according to the general proc- ess (see Extracts, Fluid), but using the drug in Xo. 40 powder, reserving the first 13 fluidounces of percolate (for 16^4 av. ounces of drug), and evapor- ating the remainder on a water bath. The menstruum is diluted alcohol. — N. F. Extract, Fluid, of Broom. (Fluid Extract of Scoparius.) Prepare according to the general proc- ess (see Extracts, Fluid). The mens- truum is diluted alcohol. — N. F. Extract, Fluid, of Bryony. Moisten 16^4 av. ounces of drug in moderately fine powder with 3 fluid- ounces of water. Allow to stand in a covered vessel for one hour, then mix intimately with 6 fluidounces of alcohol, let stand for another hour, then ex- haust by any suitable process for fluid extracts (see Extracts, Fluid), using a menstruum composed of 3 volumes of alcohol to 2 of water. Extract, Fluid, of Buchu. Prepare according to the general proc- ~ee Extracts, Fluid), the first 13K fluidounces of percolate (from 16^4 av. ounces of drug), and evaporating the balance of the percolate on a water bath at a temperature not exceeding 50 C. The menstruum is a mixture of 1 volume of water and 3 of alcohol. — U. S. P. Extract, Fluid, of Buchu, Compound. Buchu av.oz. ioy 2 Cubeb av.oz. 2. gr. 35 Juniper berries av.oz. 2. gr. 35 Uva ursi av.oz. 2, gr. 35 Alcohol, water, each sufficient Mix the drugs and reduce to No. 40 powder. Prepare the fluid extract ac- cording to Process A (see Extracts, Fluid), using a mixture of 2 volumes of alcohol and 1 of water as the mens- truum, the above mixture of drugs to make 16 fluidounces of product. — N. F. Most of the preparations of the above name which are on the market repre- sent, in each pint, 8 av. ounces of buchu, 2 av. ounces each of cubeb, juni- per and uva ursi, and 2 fluidounces of spirit of nitrous ether. Extract, Fluid, of Buchu, Juniper and Potassium Acetate, Comp'd. Buchu av.oz. 12^ Juniper av.oz. 3 Potassium acetate av.oz. 1 Alcohol, water, each sufficient Mix the buchu and juniper, reduce them to tolerably fine powder, and ex- tract by the process of the U. S. P. or X. F. (see Extracts, Fluid). The mens- truum should consist of 2 volumes of alcohol to -i of water. The percolate, after dissolving the potassium acetate in it, should measure 16 fluidounces. Extract, Fluid, of Buchu and Pareira. Mix buchu leaves and cut pareira in equal parts, reduce to fine powder, and extract by the process of the U. S. P. or X. F. (see Extracts, Fluid), using as menstruum composed of 2 volumes of alcohol and 1 of water. Extract, Fluid, of Buchu, Pareira and Uva Ursi. Make like the preceding, using 8^< av. ounces of buchu and 4^4 av. ounces of each of pareira and uva ursi, the product to measure 16 fluidounces. Extract of Buckbean. (Extractum Trifolii Fibrini.) Buckbean, cut moderately fine av.oz. 16 Alcohol fl.oz. i8J4 Water, boiling sufficient Macerate the drug with 77 fluidounces of the water for 6 hours, agitating oc- casionally, express, macerate the resi- due with 46 fluidounces more of the PHARMACEUTICAL PREPARATIONS. 135 water for 3 hours, express again, mix the two liquids, evaporate to a weight of 32 av. ounces, when cold add the al- cohol, set aside in a cool place for 2 days, filter, and evaporate the filtrate to thick extract. — Germ. Pharm. Extract, Fluid, of Buckbean. (Fluid Extract of Menyanthes.) From the leaves of Menyanthes tri- foliata (Trifolium fibrinum, Germ. Pharm.). Prepare according to Process A (see Extracts, Fluid), using the drug in No. 20 powder, and diluted alcohol as the menstruum. — N. F. Extract of Buckthorn. (Extract of Frangula.) I. Buckthorn bark, coarse powder av.oz. 8 Diluted alcohol fl.oz. 20 Water sufficient Mix the bark and diluted alcohol, macerate for 48 hours in a closed ves- sel, pack in a percolator, allow the liquid to drain, and then pass enough water through the drug to make the percolate measure 30 fluidounces. Evap- orate this percolate on a water bath to thick extract consistency. — Brit. Pharm. 1885. II. Frangula, moderately coarse powder av.oz. 4 Water fl.oz. 24 Mix the drug with 16 fluidounces of water, macerate for 24 " hours, strain with expression, upon the residue pour 8 fluidounces of boiling water, macerate again for 1 hour, strain and express, mix the two liquids, and evaporate to dryness. — D. Extract, Fluid, of Buckthorn. (Fluid Extract of Frangula.) Prepare according to the general proc- ess (see Extracts, Fluid), but using the drug in No. 40 powder, moistening 162/4 av. ounces of it with s l A fluidounces of menstruum, reserving the first 13 fluid- ounces of percolate, and evaporating the remainder on a water bath. The mens- truum is a mixture of 5 volumes of al- cohol and 8 of water. — U. S. P. The fluid extract of the Germ. Pharm. is made with a mixture of 1 volume of alcohol and 2 of water. The Germ. Pharm, directs making 100 parts by weight of fluid extract from 100 parts of drug, using a mixture of 1 volume of alcohol and 2 of water as a menstruum. Extract, Fluid, of Buckthorn, Bitter- less. (Extractum Frangulae Ex- amaratae Fluidum.) Bitterless buckthorn bark. av.oz. 16^4 Alcohol, water, each sufficient Extract the bark by the process of the U. S. P. or N. F., or any other suitable process for , fluid extracts. The mens- truum should consist of a mixture of 3 volumes of alcohol to 1 of the water, the product should measure 16 fluid- ounces. Bitterless buckthorn bark is prepared by intimately mixing 10 av. ounces of buckthorn bark in very fine powder and 1 av. ounce of calcined magnesia with 20 fluidounces of water, allowing to stand for 12 hours, drying on a water bath -with constant stirring, powdering again, and sifting. — D. Extract, Fluid, of Blackthorn. Palatable. Fluid extract of buckthorn, U. S. P fl.oz. 16 Ammoniated glycyrrhizin. . .gr. 120 Saccharin gr. 30 Solution of potassa fl.dr. 2 Water fl.oz. 2 Dissolve the saccharin and glycyrr- hizin in the water to which has been added the solution of potassa, the fluid extract of buckthorn, and mix thor- oughly. The result is an elegant prod- uct, free from nauseating or disagree- able taste. This product is, of course, somewhat weaker than a fluid extract is supposed to be. Extract, Fluid, of Burdock. (Fluid Extract of Lappa or Burdock Root.) Prepare according to the general proc- 136 STANDARD FORMULARY OF ess (sec Extracts, Fluid). The mens- truum is diluted alcohol— U. S. P. 1890. Extract of Butternut-bark. (Extract of Juglans.) Prepare according to the general proc- ess (see Extracts), but using the drug in No. 30 powder and evaporating the percolate on a water bath to pilular con- sistence. The menstruum is diluted al- cohol. — N. F. Appendix and U. S. P. 1800. Extract, Fluid, of Butternut. (Fluid Extract of Juglans.) From the inner bark of Juglans cin- erea. Prepare according to Process A (see Extracts, Fluid), using the drug in No. 40 powder, and diluted alcohol as the menstruum. Extract, Fluid, of Cactus Grandi- florus. (Fluid Extract of Cereus Grandiflorus.) The preparation sold under this name is usually a concentrated tincture, made from the freshly gathered fleshy stems, leaves and flowers, which are crushed, covered with alcohol, and macerated for 2 weeks, then expressed and filtered. Three species of plants are now gener- ally employed indiscriminately in mak- ing this preparation, viz., Cereus grandi- florus. C. Bonplandi and C. McDonaldi. Extract of Calabar Bean. (Extract of Physostigma.) I. Prepare according to the general process (see Extracts), using the drug in Xo. 80 powder. The menstruum is alcohol. The liquid is to be evaporated to dryness at a temperature not exceed- ing 50 deg. C. The product is to be ed and made to contain 2 per cent, of ether: soluble alkaloids. If it con- tains more, enough peeled Russian, licor- ice root in No. 80 powder is to be added to it to reduce it to this percent- age. Then reduce to powder, mix well, and transfer at once to well-stoppered amber-colored vials.— U. S. P. II. Calabar bean, No. 40 pow- der av.oz. 16 Alcohol fl.oz. 76 Milk sugar sufficient Mix the drug with 19 fluidounces of alcohol, set aside in a closed vessel for 48 hours, agitating occasionally, trans- fer to a percolator, and when the liquid ceases to pass, add the remainder of the alcohol so that it may slowly perco- late through the drug. Remove the marc from the percolator, subject it to pressure, add the expressed liquid to the percolate, filter, recover most of the alcohol by distillation, transfer the resi- due to a tared porcelain capsule, evap- orate to the consistence of very soft ex- tract, weigh, add three times its weight of milk sugar, and mix thoroughly. — Brit. Pharm. The extract of the Brit. Pharm. 1885 contained no milk sugar and hence was 4 times as strong as the extract of the present Brit. Pharm. Extract of Calamus. (Extract of Sweet Flag.) Calamus, cut fine av.oz. 4 Alcohol, water, each sufficient Mix the drug with 9% fluidounces of alcohol and 11^ of water, macerate for 4 days, agitating occasionally, and strain with expression. To the residue, add 4^2 fluidounces of alcohol and sH of water, macerate for 24 hours, and strain with expression.' Mix the two liquids, heat on a water bath, set aside for 2 days, filter, and evaporate the fil- trate to thick extract. — Germ. Pharm. Extract, Fluid, of Calamus. (Fluid Extract of Sweet Flag.) Prepare according to the general proc- ess (see Extracts, Fluid), moistening i6^4 av. ounces of drug with 5^ fluid- ounces of menstruum receiving the first 14^ fluidounces of percolate as the re- serve, and evaporating the weak perco- late on a water bath at not above 5c deg. C. The menstruum is a mixture of 3 volumes of alcohol and 1 of water Extract, Fluid, of Calendula. (Fluid Extract of Marigold.) From the flowering herb of Calen- dula officinalis. PHARMACEUTICAL PREPARATIONS. 137 Prepare according to Process A (see Extracts, Fluid), using the drug in No. 40 powder, a mixture of 2 volumes of alcohol and 1 of water as the mens- truum. — N. F. Extract, Fluid, of Calendula, Non- Alcoholic. Calendula (flowering herb) No. 40 powder av.oz. 16^ Glycerin fl.oz. 8 Alcohol, water, each sufficient Moisten the drug with a menstruum composed of 2 volumes of water and 1 of alcohol, and macerate for 12 hours. Percolate to exhaustion with same menstruum, recover the alcohol by dis- tillation, then evaporate carefully to 8 fluidounces, and add the glycerin. Extract, Fluid, of Canadian Hemp. (Fluid Extract of Black Indian Hemp or Apocynum or Apocy- num Cannabinum.) Prepare according to the general proc- ess (see Extracts, Fluid), using as a first menstruum, for i6}i av. ounces of drug, a mixture of 13 fluidrams of glycerin, 9^ fluidounces of alcohol and 4^4 fluidounces of water, to be followed by a mixture of 3 volumes of alcohol and 2 of water. The weak percolate is to be evaporated at not above 50 deg. C— N. F. • Extract of Cannabis Indica. (Extract of Indian Cannabis or Indian Hemp.) Moisten 16^4 av. ounces of drug in No. 20 powder with 5 fluidounces of al- cohol, and pack it firmly in a cylindri- cal percolator, then add enough alcohol to saturate the powder and leave a stratum above it. When the liquid be- gins to drop from the percolator, close the lower orifice and, having closely covered the percolator, macerate for 48 hours. Then allow percolation to pro- ceed, gradually adding alcohol, until the drug is exhausted. Distil off the alco- hol from the percolate by means of a water bath, and evaporate the residue in a porcelain dish, on a water bath, to pilular consistence. — U. S. P. The preparation of the Brii. Pharm. differs from this only in being evapor- ated to soft extract. Extract of Cannabis Indica, Alco- holic or Resinous. (Cannabin of T. & H. Smith.) Digest the drug in successive quan- tities of warm water till the expressed liquid comes away colorless, and again for 2 days, at a moderate heat, in a solution of sodium carbonate in the proportion of 1 part of salt to 2 of drug ; coloring matter, chlorophyll, and inert concrete oil are thereby removed. Ex- press and wash the residue, dry it, and exhaust it by percolation with alcohol. Agitate the percolate with milk of lime containing 1 av. ounce of lime for every av. pound of drug, filter, and to the filtrate add a small amount of sulfuric acid to precipitate the excess of lime. Also add a little animal charcoal, again filter, from the filtrate distil most of the alcohol, to the residue, contained in a porcelain capsule, add twice its weight of water, and allow the remaining alco- hol to be dissipated by spontaneous evaporation. Collect the resin and wash it with water until the washings are neither acid nor bitter, and dry the resin in thin layers. Extract, Fluid, of Cannabis Indica. (Fluid Extract of Indian Canna- bis or Indian Hemp.) Prepare according to the general proc- ess (see Extracts, Fluid), but using the drug in No. 30 powder, reserving the first 14H fluidounces of percolate (from 16^4 av. ounces of drug), and evapor- ating the remainder on a water bath at not above" 50 deg. C. The menstruum is alcohol.— U. S. P. Extract, Fluid, of Capsicum. Prepare according to the genera! proc- ess (see Extracts, Fluid), but moisten- ing i6}i av. ounces of drug with 8 fluidounces of menstruum, reserve the first 14^ fluidounces of percolate, and evaporate the remainder on a water bath. The menstruum is alcohol. J 38 STANDARD FORMULARY OF Extract, Fluid, of Cardamom, Com- pound. What is commercially sold under this title may .be made as follows : Cardamom, without cap- sules av.oz. 2>Va Cassia cinnamon av.oz. 3% Caraway av.oz. 1^4 Cochineal gr. 290 Diluted alcohol sufficient Grind the drugs to moderately fine powder, and extract with diluted alco- hol (see Extracts, Fluid), so as to ob- tain 16 fluidounces of product. This product is ten times the strength of the official tincture, which may be prepared by mixing 1 fluidounce of this with 14 fluidounce of glycerin, and 8^2 fluidounces of diluted alcohol. Extract of Cascara Sagrada. I. Prepare according to the general process given under Extracts. In this case 16 av. ounces of drugs in No. 60 powder is to be exhausted with a mix- ture of 1 volume of alcohol and 7 of water. The first 14 fluidounces of per- colate are to be reserved, the remainder is to be evaporated on a water bath not exceeding 70 deg. C. to the consistence of syrup. This is to be mixed with the reserved portion, and the whole liquid is to be evaporated at the same temperature to dryness. Reduce the extract to fine powder and add enough peeled Russian licorice root in No. 80 powder to make the whole weigh 4 av. ounces. — U. S. P. II. Moisten the drug, in No. 20 pow- der, with water, let it remain a few hours to soften and swell, then place it loosely in a percolator, and percolate with water until the drug is exhausted. Evaporate on a water bath to dryness. —Brit. Pharm. III. Cascara sagrada, No. 20 powder, Alcohol, water, each sufficient Take any suitable quantity of the bark, moisten with a mixture of 3 parts of alcohol and 4 of water, then pack in a percolator, moisten, and percolate in the usual manner until the drug is ex- hausted ; then evaporate the percolate on a water bath either to thick consist- ency or to dryness as may be desired. The yield of pilular extract is about 28 per cent., of dry extract, about 24 per cent. — D. modified. Extract, Fluid, of Cascara Sagrada. I. Prepare according to the general process (see Extracts, Fluid), reserving the first 13 fluidounces of percolate from 16^4 av. ounces of drug, and evaporat- ing the remainder on a water bath. The menstruum is a mixture of 2 vol- umes of alcohol and 3 of water. — U. S. P. The fluid extract of cascara sagrada of the market varies greatly. Some brands are sweetened, either with sac- charine or sugar, some contain licorice extract. A formula recommended for making this fluid extract is to exhaust 16 av. ounces of the drug by passing water through it, evaporating the percolate on a water bath to 12 fluidounces, adding 3 fluidounces of alcohol and 1 fluid- ounce of glycerite of licorice, and filter- ing, if necessary. II. Brit. Pharm. formula for liquid extract of cascara sagrada : Cascara sagrada av.oz. i6^4 Diluted alcohol fl.oz. 6 l / 2 Distilled water sufficient Moisten the drug with 12 fluidounces of distilled water, set the mixture aside for 6 hours, then place it loosely in a percolator, and percolate with more water until the drug is exhausted. Evaporate the percolate to g l / 2 fluid- ounces, and add the diluted alcohol. Extract, Fluid, of Cascara Sagrada, Aromatic. (Cascara Aromatic.) The bitterness of cascara sagrada is removed by means of an insoluble alkali such as lime or magnesia; the taste of the preparation is further improved by adding sugar, saccharin, licorice, and flavoring oils and spirits. The following formulas are all excellent : PHARMACEUTICAL PREPARATIONS. 139 I. Cascara sagrada, fine pow- der av.oz. 16^4 Extract licorice gr. 318 Glycerin fl.oz. ZY 2 Alcohol T. fl.oz. 4 Benzosulphinide gr. 8 Oil anise m. 20 Oil coriander m. 1 Oil wintergreen m. 1 Boiling water, to make fl.oz. 16 Mix the powdered drug and the mag- nesia with 32 fluidounces of boiling water, set aside for 2 hours, stirring occasionally, and then pack in a perco- lator. Pour on boiling water and allow percolation to proceed until the drug is exhausted. Evaporate the percolate to 8 z / 2 fluid ounces, and while still warm, dissolve in it the extract of licorice. When cold, add the glycerin, then the alcohol in which the benzosulphinide and the oils have been dissolved, and finally sufficient water to make the fluidextract measure 16 fluidounces. — U. S. P. II. N. F. (which calls it Bitterless Fluid Extract of Cascara Sagrada) : Cascara sagrada, fine pow- der av.oz. i6>}4 Quicklime gr. 360 Sugar av.oz. 7 Oil of coriander drops 10 Oil of anise drops _ 6 Water sufficient Slake the lime, add 32 fluidounces of water, stir in the drug, and digest on a water bath for 6 hours, or until the bitter taste has become faint. Pack the magma into a percolator, allow it to drain, then percolate with water until the drug is exhausted. Evaporate the percolate to 12 fluidounces, dissolve the sugar in this liquid, and then add the oils, shake well, filter if necessary and add enough water to make 16 fluid- ounces. This preparation is said to keep well, even though it contains no alcohol. The flavor may be varied by adding oil of cinnamon, wintergreen, fennel, etc. Lic- orice may be added either by mixing the ground root with the drug or by in- corporating extract or glycerite with the evaporated liquid. III. Steven's process: Cascara sagrada, No. 40 powder av.oz. i7 x A Calcined magnesia av.oz. i}i Water fl.oz. 18 Alcohol fl.oz. 13 Glycerin ' fl.oz. 4 Extract of licorice, puri- fied av.oz. 454 Saccharin gr. 30 Oil of fennel drops 5 Diluted alcohol sufficient Mix the first two ingredients very in- timately, moisten with water and mac- erate for several hours. Then pack the mixture in a percolator and allow to macerate about 48 hours; then add the alcohol and allow to macerate 12 hours longer. Now start percolation with di- luted alcohol and continue until the drug is exhausted. The percolation should be allowed to go on very slowly at first, the heavier portion being re- served to the amount of about 13 fluid- ounces and the remainder in succession to about 16 fluidounces. Recover the alcohol, commencing with the most di- lute of the liquors, and evaporate until the whole is reduced to 12 fluidounces, including the glycerin ; to this product add the extract of licorice, saccharin and oil of fennel, the whole to measure 16 fluidounces. If the total volume falls short of 16 fluidounces, add enough di- luted alcohol. This process may be varied slightly as follows : Evaporate the percolate to 8 fluidounces (without the glycerin), and add 8 fluidounces of glycerite of licorice, the saccharin and oil. IV. Urban's process (recommended by Hemm) : Cascara sagrada, No. 60 powder av.oz. 1634 Licorice root, No. 40 pow- der av.oz. 2 l / 2 Freshly slaked lime av.oz. 1^4 Compound spirit of orange, .m. 100 Solution of saccharin fl.oz. 1 Alcohol fl.oz. 8 Glycerin fl.oz. 4 Water, diluted alcohol, each sufficient HO STANDARD FORMULARY OF Mix the freshly slaked lime with the cascara sagrada and licorice root, add 16 fluidounces of water, mix thoroughly, pass through a No. 20 sieve, macerate for 24 hours, and dry at a temperature of 40 to 50 deg. C. Mix the alcohol and glycerin with 4 fluidounces of water, moisten the drugs with 6]/ 2 fluidounces of this menstruum and then extract in the usual manner for fluid extracts, using diluted alcohol as a menstruum after the above liquid has all been add- ed to the drugs. Reserve the first 13^ fluidounces of percolate, evaporate the remainder to soft extract, dissolve the latter in reserve percolate, add the solu- tion of saccharin and the spirit and then enough diluted alcohol to make 16 fluidounces ; filter after several days, if necessary. V. This preparation may also be pre- pared from the bitterless fluid extract of cascara sagrada by the addition of extract or glycerite of licorice and aro- matics. Extract, Fluid, of Cascara Sagrada, Bitterless or Tasteless. (Ex- tractum Cascarae Sagradse Ex- amaratee Fluidum — Tasteless Liquid Extract of Cascara Sag- rada, Brit. Form.) I. Bitterless cascara sagrada. av.oz. 17^ Alcohol, water, each sufficient Use as menstruum a mixture of 3 volumes of alcohol with one of water. The process of extraction may be that of the U. S. P. or N. F., or any other suitable process for fluid extracts. The product should measure 16 fluidounces. Bitterless cascara sagrada is made by intimately mixing 10 av.ounces of cas- cara sagrada in fine powder and 1 of calcined magnesia with 20 fluidounces of water, allowing to stand for 12 hours, then drying on a water bath with con- stant stirring, powdering again, and sifting.— D. Modified. This is Dieterich's formula for bitter- less cascara sagrada bark. II. Gilpin's formula is as follows: Cascara sagrada, powder, .av.oz. 10 Licorice root, powder av.oz. 2%, Calcined magnesia gr. 90 Clove, powder gr. 45 Mix the powders intimately, moisten with water and knead thoroughly. Transfer the mass to a closed drying chamber and subject to a temperature of 82 deg. C. for 48 hours. Then per- mit the moisture to escape from the chamber, dry the powder thoroughly, repowder, and sift. III. Cascara, No. 40 powder. . .av.oz. 20 Calcined magnesia, light. . .av.oz. 2 Distilled water, alcohol, each, to make fl.oz. 20 Mix the powders, moisten thoroughly with water, macerate for 24 hours, dry thoroughly over a water bath, and re- duce the dry mass to powder. Moisten this powder with 20 fluidounces of a mixture of o volumes of alcohol and 5 of water, pack lightly in a percolator, and allow percolation to proceed, using the same menstruum, until the drug is exhausted. Reserve the first 17 fluid- ounces of percolate, distil ofT the alcohol from the remainder, evaporate the resi- due to soft extract, dissolve this in the reserved percolate, and add enough of the mixture of 9 volumes of alcohol and 5 of water to make 20 fluidounces of percolate. — Brit. Form. IV. Edel's process : Cascara sagrada, coarse powder av.oz. i6|4 Calcined magnesia av.oz. i}£ Alcohol, water, glycerin. each sufficient Mix the drug and magnesia, moisten with water and allow to macerate for several hours. Then pack the mixture in a percolator and allow to macerate for 48 hours; add 12 fluidounces of al- cohol, allow to macerate for 12 hours longer, and finally begin, percolation using diluted alcohol as the menstruum. The first 12 fluidounces should be re- served, and percolation continued to ex- PHARMACEUTICAL PREPARATIONS. 14:1 haustion. Recover the alcohol and evap- orate the percolate to soft extract, and dissolve it in the reserved portion, add- ing sufficient glycerin to make 16 fluid- ounces. The bitterless fluid extracts may be used as they are or be made still more pleasant by the addition of licorice and cinnamon or other aromatics. See Ex- tract, Fluid, of Cascara Sagrada, Aro- matic, also Extract, Fluid, of Cascara Sagrada, Water-Miscible. Extract, Fluid, of Cascara Sagrada, Water-Miscible. Cascara sagrada, No. 20 powder av.oz. 16^4 Alcohol fl.oz. 4 Distilled water sufficient Moisten the bark with water, allow to remain a few hours to soften and swell, pack loosely in a percolator, and percolate with more water until ex- hausted. Evaporate on a water bath to the consistency of a brittle extract, which, when cold, treat with cold water until thoroughly disintegrated. Allow this to stand and settle. Strain through flannel, and evaporate the strained liquor to 12 fluidounces, add the alcohol, when cold, and filter if necessary. This preparation does not deposit either on keeping or on diluting with water, and, although bitter, is free from nauseous taste and smell. Extract of Cascarilla. Cascarilla, coarse powder. av.oz. 16 Water, boiling fl.oz. 123 Macerate the drug with 77 fluidounces of the water for 24 hours at a tempera- ture of 15 to 20 deg. C, express, mac- erate the residue with the remainder of the boiling water for 24 hours, again express, mix the two liquids, evaporate to a weight of 32 av.ounces, set aside in a cool place for several days, decant the clear liquid, and evaporate to thick extract. — Germ. Pharm. Extract, Fluid, of Catechu, Comp'd. The article sold under this name may be made as follows: Catechu, powder av.oz. 7 Cassia cinnamon, powder. . .av.oz. 2> l A Clean, dry sand, diluted al- cohol, each sufficient Mix the two drugs and then add about twice the volume of sand; extract this mixture by the usual method for making fluid extracts, using diluted alcohol as a menstruum, the product to measure 16 fluidounces. Extract, Fluid, Catnep. Catnep in No. 40 powder. Fluidex- tract by type process A, using 3 volumes of alcohol and 4 of water.— N. F. Extract, Fluid, of Celery Fruit. From the fruit of Apium graveolens. Prepare according to Process A (see Extract, Fluid), using the drug in No. 40 powder, and alcohol as the mens- truum. — N. F. Extract of Chamomile. (Extract of Anthemis.) English (Roman) chamo- mile flowers av.oz. 4 Oil of chamomile drops 5 Distilled water fl.oz. 40 Boil the flowers with the water until the volume is reduced one-half, strain off the liquid, express the residue, mix the two liquids, filter, and evaporate the filtrate to soft extract, adding the oil towards the end of the process. — Brit. Pharm. Extract, Fluid, of (Roman) Chamo- mile. Prepare fluid extract by the usual process (see Extracts, Fluid), using a mixture of 3 volumes of alcohol and 2 of water as the menstruum. Extract, Fluid, of Chestnut. (Fluid Extract of Castanea.) Castanea, No. 30 powder, .av.oz. i6^4 Glycerin fl.dr. 13 Alcohol, water, each sufficient Pour 5 pints of boiling water upon the powder, allow it to macerate for 2 hours, then express the liquid, transfer the residue to a percolator, and pour water upon it until the powder is ex- hausted. Evaporate the united liquids 142 STANDARD FORMULARY OF on a water bath to 32 fluidounces, al- low this to cool and add g l / 2 fluidounces of alcohol. When the insoluble matter has subsided, separate the clear liquid, filter the remainder, evaporate the uni- ted liquids to 11 J 2 fluidounces, allow this to cool add the glycerin and enough alcohol to make the fluid extract meas- ure t6 fluidounces. — N. F. Extract, Fluid, of Chioanthus. Drug in No. 30 powd. Type process A, 3 volumes alcohol and 1 volume water.N. F. Extract, Fluid, of Chirata. Prepare according to the general formula (see Extracts, Fluid), but using the drug in No. 30 powder, moistening 16^4 av. ounces of it with 5H of men- struum, reserving the first 13^ fluid- ounces of percolate and evaporating the second percolate on a water bath. The menstruum is diluted alcohol. — U. S. P. Extract of Cinchona. I. Make according to the general process (see Extracts) except that 1 av. pound of the drug (calisaya bark) is to be moistened with $y 2 fluidounces of men- struum before packing in the percola- tor, continuing percolation until 62 fluid- ounces of percolate are obtained or the drug is exhausted, and evaporating the percolate on a water bath to pilular consistence. The menstruum is a mix- ture of 46 fluidounces of alcohol and 15^2 fluidounces of water for 1 av.pound, the percolation to be continued then with diluted alcohol.— N. F. Cinchona used for any U. S. P. prep- aration should contain not less than 5 per cent, of total alkaloids and not less than 2 l / 2 per cent, of quinine. IT. Germ. Pharm. formula for alcoholic extract of cinchona : Red cinchona, coarse powd.av.oz. 16 Alcohol, water, each sufficient Macerate the cinchona with a mixture *f 66 fluidounces of alcohol and 22 of water for 6 days at a temperature of 15 to 20 deg. C, agitate frequently, express, macerate the residue with the same amount of alcohol and water for 3 days, express again, mix the two liquids, let stand for 2 days, filter, and evaporate the filtrate to dry extract. See also No. III. III. Germ. Pharm. formula for aqueous extract of cinchona, or the so-called "extractum chinae frigidum para- tum" : Red cinchona, coarse powd.av.oz. 16 Water pints 19 Mix the drug with one-half the water, set aside for 48 hours at a temperature of 15 to 20 deg. C. and express. Add the remainder of the water, let stand for 48 hours as before, and express. Mix the two liquids, evaporate to a weight of 2> 2 av.ounces, allow to cool, filter, and evaporate the filtrate to a thin extract. See also No. II. Extract, Fluid, of Cinchona. (Fluid Extract of Calisaya.) I. Prepare according to the general proc- ess (see Extracts, Fluid), but moisten- ing i6}£ av.ounces of drug (yellow cin- chona) with s x / 2 fluidounces of men- struum, reserving the first n l A fluid- ounces of percolate, and evaporating the remainder on a water bath. The men- struum for this amount of drug is a mixture of 13 fluidrams each of glycerin and water and i2^i fluidounces of alco- hol, to be followed by a mixture of 4 volumes of alcohol and 1 of water. The product is to be assayed and is to be made to contain 4 grams of anhydrous ether-soluble alkaloids in 100 cc. ; if it contains more, add enough of the mix- ture of 4 volumes of alcohol and 1 of water to reduce it to this standard. — U. S. P. II. Brit. Pharm. formula for liquid ex- tract of cinchona: Red cinchona, No. 60 powd.av.oz. 12^ Hydrochloric acid fl.oz. 3 Glycerin fl.oz. \Vz Alcohol, distilled water sufficient PHARMACEUTICAL PREPARATIONS. 143 Mix the drug with 60 fluidounces of distilled water to which the acid and glycerin have previously been added, set aside in a covered vessel for 48 hours, stirring frequently, and transfer to a percolator. When the liquid ceases to pass and the contents of the percolator have been properly packed, continue the percolation with distilled water until 180 fluidounces of percolate have been ob- tained or until it no longer gives a precipitate when mixed with an excess of solution of potassium hydrate. This percolate is then to be evaporated, in a porcelain or enameled-iron vessel at a temperature not exceeding 82 deg. C, until reduced to 12 fluidounces. The liquid is now to be assayed for total alkaloids, and every volume that contains 5 grams of total alkaloids is to be brought to a volume of 85 cc, either by evaporation or by addition of distilled water; to this is to be added i2 z / 2 cc. of alcohol and enough distilled water to make 100 cc. The product contains 5 grams of to- tal alkaloids in 100 cc. (5 grains in no minims). The bark (red only being recognized) is also to be standardized to contain be- tween 5 and 6 per cent, of total alka- loids, of which not less than half should consist of quinine and cinchonidine. Extract, Fluid, of Cinchona, Aqueous. Red cinchona, No. 40 powd..oz. 16 Hydrochloric acid dr. 4 Glycerin fl.oz. 2 Alcohol, Water, each, q. s. Mix the hydrochloric acid and glyc- erin with five pints water and moisten the drug with 6 fluid ounces of the mix- ture. Pack in a cylindrical percolator, pour on additional menstruum and pro- ceed in the usual way to percolate 10 fluid ounces. Then add enough alcohol and water to the percolate to make it, when completed, 12% by volume of abso- lute alcohol and 5% total alkaloids. — N. F. Extract, Fluid, of Coca. Prepare according to the general proc- ess (see Extracts, Fluid), moistening 16^4 av.ounces of the drug with 7 l / 2 fluidounces of the menstruum (di- luted alcohol), reserving the first nj4 fluidounces of percolate and evapora- ting the remainder at not above 50 deg. C. The product is to be assayed and is to be made to contain y 2 gram of ether- soluble alkaloids in 100 cc. ; if it con- tains more than this amount, diluted alcohol is to be added to it to reduce it to this standard.— U. S. P. Extract, Fluid, of Cocillana. Drug in No. 20 powder, process A; menstruum, 3 volumes alcohol to 1 vol- ume of water. — N. F. Extract of Cod-Liver Oil. Cod-liver oil, brown av.oz. 15 Sodium carbonate, pure, monohydrated gr. 290 Distilled water fl.oz. 8 Alcohol -s fl.oz. 27 Dissolve the sodium salt in the water,, add to the oil, agitate repeatedly and thoroughly during 24 hours, then allow to remain quiet for 12 hours, and decant the oily layer. Mix the latter with 18 fluidounces of alcohol, agitate vigorous- ly for half an hour, set aside for a short time, decant the alcoholic layer, mix the oily portion with the remainder of the alcohol, agitate thoroughly, allow to stand, and again decant the alcoholic layer. Mix the two alcoholic liquids and distil off the alcohol. The residue is a so-called "extract of cod-liver oil." The product should be kept in a well- closed bottle protected from light. — H. modified. Light-colored oil is also used for ma- king this "extract," but the yield is smaller. The light oil requires no pre- liminary washing with alkali and water which are used to remove acids from the dark oil. Extract, Fluid, of (Green) Coffee. From the commercial, unroasted seeds of Co-ffea arabica. 144 STANDARD FORMULARY OF Prepare according to Process B (see Extracts, Fluid), using the drug in No. 20 powder, the first menstruum being a mixture of I fluidounce of glycerin, 4 of alcohol and 11 of water (for 16^4 av.ounces of drug), the second a mix- ture of 1 volume of alcohol and 3 of water. It is recommended that the best qual- ity of either of the commercial varieties known as "Java," or "Mocha," coffee be employed for this preparation. Extract, Fluid, of (Roasted) Coffee. Prepare extactly like Extract, Fluid, of (Green) Coffee, which see, using roasted coffee (same varieties preferred) instead of green coffee. — N. F. Extract of Colchicum Corm. (Extract of Colchicum Root.) Prepare according to the general proc- ess (see Extracts), but moistening 1 av.pound of drug with 8 fluidounces of menstruum, percolating the drug till ex- hausted, and evaporating the percolate on a water bath at a temperature not exceeding 80 deg. C. The menstruum for 1 av.pound of drug is a mixture of lY 2 fluidounces of acetic acid and 23 fluidounces of water, the percolation to be continued with water. The product is assayed and is to con- tain 1.4 per cent, of colchicine. If found to contain more than this percentage, enough powdered sugar of milk should be added to reduce it to this standard. — U. S. P. Extract, Fluid, of Colchicum Root. Prepare according to the general proc- ess (see Extracts, Fluid). The men- struum is a mixture of 2 parts of alcohol and 1 of water. — N. F. Appendix and U. S. P. 1890. Extract, Fluid, of Colchicum Seed. Prepare according to the general proc- ess (see Extracts, Fluid), extracting 16^4 av.ounces of the drug in No. 50 powder with a mixture of 2 volumes of alcohol and 1 of water, first moistening with 5 fluidounces of menstruum. Re- serve the first 12 fluidounces of perco- late and evaporate the remainder to soft extract. The product is to be assaved and made to contain T / 2 gram of colchi- cine in 100 cc. ; if it contains more than this amount. — U. S. P. Extract of Colocynth. I. Colocynth, dried, and freed from seeds av.oz. 8 Diluted alcohol sufficient Reduce the drug to coarse powder by grinding or bruising, macerate in 27 fluidounces of diluted alcohol for 4 days, stirring occasionally, express strongly, and strain through flannel. Pack the residue, previously broken up with the hands, firmly in a cylindrical percolator, cover it with the strainer, and gradu- ally pour diluted alcohol upon it until the percolate and the expressed liquid, mixed together, measure 38^ fluid- ounces. Distil off the alcohol from the mixture on a water bath, evaporate the residue to dryness, and reduce the dry mass to powder. — U. S. P. The product should be kept in well- stoppered bottles. II. Colocynth, coarsely cut, with the seeds av.oz. 16 Alcohol, water, each sufficient Macerate the drug with a mixture oi 18 pints of alcohol and 6 pints of water for 6 days, at a temperature of 15 to 20 deg. C, agitating occasionally, ex- press, macerate the residue for 3 days with a mixture of 138 fluidounces of alcohol and 115 of water, agitating oc- casionally, express again, mix the two liquids, and evaporate to dryness — Germ. Pharm. Extract of Colocynth, Compound. Aloes, purified av.oz. 2 Extract of colocynth gr. 280 Resin of scammong, fine powder gr. 245 Castile soap, dried, coarse powder gr. 245 Cardamom, No. 60 powder, .gr. 105 Alcohol fl.dr. 3 Heat the aloes, contained in a suitable vessel, on a water bath, until it is com- pletely melted, then add the alcohol, soap, extract of colocynth and resin of scammony, and heat the mixture at a PHARMACEUTICAL PREPARATIONS. 145 temperature not exceeding 120 deg. C. until it is perfectly homogeneous and a thread taken from the mass becomes brittle when cool. Then withdraw the heat, thoroughly incorporate the carda- mom with the mixture, and cover the vessel until the contents are cold. Then reduce to fine powder. — U. S. P. Keep in well-stoppered bottles. This is a preparation that every phar- macist should make for himself, owing to the notoriously variable and inferior character of the commercial product. The preparation of the Brit. Pharm. is practically the same, although extract of barbadoes aloes is used instead of purified aloes, curd soap instead of cas- tile soap, and the pulp of colocynth is directed to be extracted instead of using the extract itself. Extract of Columbo Columbo, coarse powder, Water, alcohol, each sufficient Take any suitable quantity of drug, moisten with a mixture of 4 parts of alcohol and 5 of water, then pack in a percolator, macerate and percolate in the usual manner with the same menstruum until the drug is exhausted, then evapo- rate to soft extract or dryness on a water bath. — D. modified. The yield is 9 to 11 per cent. Extract, Fluid, of Columbo. (Fluid Extract of Calumba.) Prepare according to the general proc- ess (see Extracts, Fluid), but using the drug in No. 20 powder, moistening i6}i av.ounces of it with 5 fluidounces of menstruum, collecting, the first ii-$4 fluidounces of percolate as the residue, and evaporating the remainder of the percolate on a water bath. The men- struum is a mixture of 7 volumes of alcohol and 3 of water. — N. F. Extract, Fluid, of Condurango. (Liquid Extract of Condurango.) I. Exhaust the drug by any suitable process for fluid extracts (see Extracts, Fluid), moistening i6^i av.ounces of drug with a mixture of 22 fluidrams of alcohol, 4 fluidounces of water and 10 fluidrams of glycerin, then percolating with a mixture of 2 volumes of alcohol and 5 of water. — Germ. Pharm. modi- fied. II. Prepare the fluidextract by Process A., using a menstruum of diluted alco- hol. The drug should be in No. 30 powder. — N. F. Extract of Conium. (Extract of Hem- lock.) Make according to the general process (see Extracts), but using the drug (which is the fruit, or so-called "seed") in No. 40 powder and moistening 1 av.pound of drug with 4^ fluidounces of menstruum. The latter, for 1 av. pound of drug, is a mixture of 2^2 fluid- drams of acetic acid and 15 fluidounces of diluted alcohol, to be followed by diluted alcohol.— N. F. Extract, Fluid, of Conium. (Fluid Extract, of Hemlock.) I. Prepare according to the general proc- ess (see Extracts, Fluid), but using the drug (which is the fruit or so-called "seed") in No. 40 powder, moistening 16^4 av.ounces of it with 5 fluidounces of menstruum, reserving the first 13 fluidounces of percolate, and evapora- ting the remainder at not above 50 deg. C. The menstruum is a mixture 2 T / 2 fluidrams of 36 per cent, acetic acid with 15^ fluidounces of diluted alcohol, to be followed by diluted alcohol. The product is to be assayed and made to contain 0.45 gram of coniine in 100 cc. ; if it contains more, enough diluted al- cohol is to be added to reduce it to this standard. — N. F. II. Conium fruit, No. 40 pow- der av.oz. 16^4 Acetic acid m. 100 Alcohol, 60 per cent, by vol- ume, to make fl.oz. 16 Mix the acid with 16 fluidounces of 146 STANDARD FORMULARY OF the alcohol, and exhaust the drug by percolation, using alcohol without acid when the acid menstruum is all con- sumed; reserve the first 13^ fluid- ounces of percolate.— Brit. Form. Extract, Fluid, of Corn Silk. (Fluid Extract of Zea— Extractum Stig- matum Maydis Fluidum.) From the stigmata of Zea Mays (In- dian Corn). Prepare according to Process A (see Extracts, Fluid), using the drug in No. 40 powder, and diluted alcohol as the menstruum. — N. F. Such a preparation is, however, infe- rior to one made from the fresh drug as follows : Corn silk, fresh av.oz. 16 Alcohol fl-oz. 16 Mix in a well-closed vessel, macerate for 7 days, then express, and filter, if necessary. Extract, Fluid, of Coto. Prepare according to Process A (see Extracts, Fluid), using the drug in No. 60 powder, and a mixture of 9 volumes of alcohol and 1 of water as the men- struum. — N. F. Extract of Coto, Saccharated. Exhaust 1 av. pound of finely pow- dered coto bark with alcohol, making a fluid extract in the usual manner, then evaporate this on a water bath to soft extract, add 4 av. ounces of powdered milk sugar, evaporate the mixture at a low temperature to dryness, powder, then add enough sugar of milk to make 1 av. pound, triturate the whole until well mixed and reduced to fine powder. Extract, Fluid, of Cotton Root Bark. Prepare according to the general proc- ess (see Extracts, Fluid), but using the drug in No. 30 powder, moistening i6^4 av. ounces of drug with 8 fluidounces of menstruum. The menstruum for 16^4 av.ounces of drug is a mixture of 4 fluidounces of glycerin and 12 of alcohol, to be followed by alcohol — U. S. P. 1890. Extract of Couch-Grass. (Extract of Triticum.) Couch-grass, cut av.oz. 8 Water, boiling fl.oz. 38 Digest for 6 hours, strain, boil the liquid down to about 3 fluid or av. ounces, filter, and evaporate to a thick extract. — Germ. Pharm. (2nd). Extract, Fluid, of Couch-Grass. (Fluid Extract of Dog-Grass or Triticum — Extractum Fluidum Graminis.) I. Couch-grass, finely cut av.oz. 16^ Alcohol, water, each sufficient Pack the drug in a cylindrical perco- lator, pour boiling water upon it, and allow percolation to proceed, supplying hot water as required until the drug is exhausted. Evaporate the percolate to 12 fluidounces, add, when cool, 4 fluid- ounces of alcohol, mix well, and set aside for 48 hours. Then filter the liquid, and add to the filtrate enough of a mixture of 3 volumes of water with 1 of alcohol to make 16 fluidounces of mixture. — U. S. P. II. The following is a quicker proc- ess than that of the U. S. P., and yields a product equally good: Couch-grass, cut av.oz. i6}4 Alcohol fl.oz. 4 Water sufficient Boil the drug for one-half hour with 5 pints of water, strain and express ; boil the residue again in the same way with the same amount of water, strain again and express. Mix the two decoc- tions, evaporate them to 12 fluidounces, add 4 fluidounces of alcohol, filter, and add enough water through the filter, if necessary, to make 16 fluidounces. III. The commercial fluid extract is usually made by reducing the drug to powder and extracting by the usual process of percolation for fluid extracts, using a mixture of 1 volume of alcohol and 3 volumes of water as the men- struum. _ PHARMACEUTICAL PREPARATIONS. 147 IV. Brit. Form, formula for liquid ex- tract of couch-grass : Couch-grass, No. 20 oowder.av.oz. 8J4 Alcohol, distilled water, each sufficient Moisten the drug with 3 fluidounces of water, pack in a percolator, and pour on boiling distilled water until the drug is exhausted. Evaporate the percolate to 12 fluidounces, add to it 4 fluidounces of alcohol, set aside 48 hours, filter, and through the filter add enough of a mix- ture of I volume of alcohol and 3 of water to make the filtrate measure 16 fluidounces. This makes a preparation which is only one-half the strength of a fluid extract. Extract Liquid of Couch-Grass. (Mellago Graminis.) Extract of couch-grass av.oz. 7 Water fl.oz. 3 Dissolve the extract in the water. This preparation decomposes very readily and must be made only as re- quired — H. This preparation need not be made from the extract; it may be directly from the drug, then evaporating the in- fusion to the consistence of honey. Extract, Fluid, of Cramp Bark. (Fluid Extract of Viburnum Op- ulus.) Prepare according to the general proc- ess (see Extracts, Fluid), but moisten- ing 16^4 av.ounces of drug with 5 fluid- ounces of menstruum, reserving the first i3 J / 2 fluidounces of percolate, and evap- orating the remainder on a water bath. The menstruum is a mixture of 2 vol- umes of alcohol and 1 of water. — N. F. Extract, Fluid, of Cubeb. Prepare according to the general proc- ess (see Extracts, Fluid), but moisten- ing i6$£ av.ounces of drug with 3^2 fluidounces of menstruum, reserving the first i4 l / 2 fluidounces of percolate, and evaporating the remainder on a water bath. The menstruum is alcohol. — N. 10 Extract of Culver's Root. (Extraot of Leptandra.) Evaporate 4 fluidounces of fluid ex- tract in a porcelain dish by means of a water bath at a temperature not exceed- ing 70 deg. C. with constant stirring to complete dryness. Reduce the product to fine powder and add enough peeled Russian licorice root in No. 80 powder to make the product weigh 1 av. ounce. -N. F. . Extract, Fluid, of Culver's Root. (Fluid Extract of Leptandra.) Prepare according to the general proc- ess (see Extracts, Fluid), reserving the first I3 J A fluidounces of percolate from 16^4 av.ounces of drug and evaporating the remainder on a water bath. The menstruum is a mixture of 3 volumes of alcohol and 1 of water.— N. F. Extract, Fluid, of Damiana. (Fluid Extract of Turnera — Liquid Ex- tract of Damiana.) I. Prepare according to Process A (see Extracts, Fluid), using the drug in No. 20 powder, and a mixture of 2 volumes of alcohol and 1 of water as the men- struum. — N. F. II. Extract the drug in No. 60 powder with 60 per cent, (by volume) alcohol, using 16M av.ounces of drug to make 16 fluidounces of product. — Brit. Form. Extract of Dandelion. (Extract of Taraxacum. I. Exhaust the dried drug in the usual manner (see under Extracts), using the drug in No. 30 powder and a menstruum composed of 1 part of alcohol and 7 of water. Exhaust the drug and evaporate the whole of the liquid on a water bath to pilular consistence. — U. S. P. In the U. S. P. 1890, the fresh drug was contused and expressed and the product evaporated to pilular consist- ence. II. The Brit. Pharm. directs the fresh root to be contused, express the juice, allow the feculence to subside, 148 STANDARD FORMULARY OF heat the liquid to ioo cleg. C, maintain the temperature for 10 minutes, strain, and evaporate the liquid to soft extract. III. Dandelion, cut moderately fine av.oz. 16 Alcohol fl.oz. 1&/2 Water sufficient Macerate the drug with 77 fluidounces of water for 48 hours at a temperature of 15 to 20 deg. C, agitating occasion- ally, express, macerate the residue in the same manner with 46 fluidounces of water for 12 hours, again express, mix the two liquids, evaporate to a weight of },2 av. ounces, when cold add the al- cohol, set aside in a cool place for 2 days, filter, and evaporate the filtrate to thick extract.— Germ. Pharm. The root should be collected before flowering time. Extract, Fluid, of Dandelion. I. Prepare according to the general formula (see Extracts, Fluid), but using the drug in No. 30 powder, moistening i6^4 av. ounces of it with 5 fluidounces of menstruum (diluted alcohol), reserv- ing the first 13 fluidounces of percolate and evaporating the remainder on a water bath to soft extract. Dissolve this in the reserved percolate, add 6 fluidrams of solution of sodium hydrate, and enough diluted alcohol to make 16 fluidounces. The alkali neutralizes the taraxacic acid and retains the tar- axacin and taraxacerin in solution. — U. S. P. IT. Brit. Pharm. formula for liquid ex- tract of dandelion : Dandelion root, dried, No. 20 powder av.oz. 16M Alcohol fl.oz. 20 Distilled water sufficient Macerate the drug with the alcohol mixed with 12 fluidounces of water, in a closed vessel, for 48 hours, express 8 fluidounces of liquid, mix the residue with 32 fluidounces of distilled water, set aside for 48 hours, express again, evaporate this liquid to 8 fluidounces, mix this residue with the previous liquid, add enough water, if necessary, to make 16 fluidounces, and filter. Extract of Digitalis. Evaporate the fluid extract in a por- celain dish on a water bath at a tem- perature not exceeding 50 deg. C, stir- ring constantly, until reduced to pilular consistence. Extract, Fluid, of Digitalis. Prepare according to the general proc- ess (see Extracts, Fluid), reserving the first 13^2 fluidounces of percolate re- ceived from 16^4 av. ounces of drug. The menstruum is diluted alcohol. The weak percolate is to be evaporated at not above 50 deg. C— U. S. P. Extract, Fluid, of Dioscorea. Dioscorea in No. 30 powder. Prepare the fluidextract by Process A., using a menstruum of three volumes of alcohol and one volume of water. — N. F. Extract, Fluid, of Dogwood. (Fluid Extract of Cornus.) Prepare according to Process B (see Extracts, Fluid), using the drug in No. 60 powder, a mixture of 2^ fluidounces of glycerin with 14 fluidounces of dilu- ted alcohol being the first menstruum (for 16^ av.ounces of drug), and dilu- ted alcohol the second menstruum. — N. F. and U. S. P. 1880. Extract, Fluid, of Echinacea. Echinacea in No. 40 powder. Extract by Process A., using a mens- truum of four volumes of alcohol and one volume of water. — N. F. Extract of Ergot. (Ergotin.) Hydrochloric acid m. 40 Petroleum benzin, q. s. Alcohol, distilled water, each sufficient Percolate the drug with the benzin, until a drop of the percolate leaves no greasy stain when evaporated from blot- ting paper. PHARMACEUTICAL PREPARATIONS. 149 Reject this percolate and remove and dry the ergot. Then re-pack in the per- colator and percolate with a mixture of 7 fluid ounces, alcohol and \ l / 2 fluid ounces water, to which the hydrochloric acid has been added. When the liquid begins to drop from the percolator, close the lower orifice, and having closely cov- ered the percolator, macerate for 48 hours. Then allow percolation to pro- ceed, gradually adding menstruum, using the same proportions of alcohol and water as before, until the drug is ex- hausted. Evaporate the percolate in a porcelain dish by means of a water bath, at a temperature not exceeding 70 deg. C, to a pilular consistence. — U. S. P. This process is simpler and much pre- ferable to that in the former edition, as the ergot is now deprived of its oil be- fore extraction. In the former process, the use of sodium carbonate was not nearly so satisfactory, owing to the somewhat soapy product. All the alkaloid (cornutine) is re- tained in solution, while much useless matter such as fixed oil, resin, coloring matter, etc., is removed ; a small amount of sodium chlorid remains in solution, but this does no harm. The extract is of the consistency of thick honey, rep- resents 8 times its weight of drug, makes a perfectly clear solution with water, and is well adapted for hypo- dermic use. It is almost needless to say that the ergotin or extract of ergot of commerce is not made by any such careful method. Usually the drug is extracted with a more or less aqueous menstruum, and the liquid is evaporated to extract con- sistency. Bon jean's ergotin was origi- nally made by exhausting powdered er- £0t with cold water by percolation, heat- ing the percolate to 90 deg. C, filtering, evaporating the filtrate to a syrupy con- sistence, allowing to cool, adding alcohol in considerable excess to precipitate gummy and albuminous matter, allow- ing to stand, decanting the clear liquid, or else filtering, and evaporating the decantate or filtrate on a water bath to soft extract. The ergotin of Wiggers, which is probably no longer in use, was simply a dried alcoholic extract of ergot. II. Ergot, No. 40 powder av.oz. 8 Diluted hydrochloric acid. . .fl.dr. 3 Sodium carbonate, crystal, pure gr. 70 Alcohol, distilled water, each .sufficient Moisten the drug with 8 fluidounces of a mixture of 2 volumes of alcohol and 1 of water, pack into a percolator, and percolate with the same menstruum until exhausted. Evaporate the perco- late to 2 fluidounces, add 2 fluidounces of distilled water, and filter when cold, washing the residue on the filter with a small quantity, of distilled water. Add the acid to the filtrate, set aside for 24 hours, filter, wash the residue on the filter with distilled water until the wash- ings are no longer acid, adding the washings to the filtrate. Add the so- dium carbonate to the liquid, and evap- orate to soft extract.— Brit. Pharm. III. Ergot, coarse powder av.oz. 8 Distilled water fl.oz. 31 Alcohol fl.oz. 4^4 Mix the drug with one-half of the water, set aside for 6 hours where it will be at a temperature of 15 to 20 deg. C, agitating occasionally, and express. Macerate the residue in the same man- ner with the same amount of water, and again express. Mix the two liquids, evaporate them to a weight of 4 av.- ounces, and add the alcohol. Set aside for 3 days, agitating occasionally, filter, 150 STANDARD FORMULARY OF and evaporate the filtrate to thick ex- tract. — Germ. Pharm. The yield is about 15 per cent. IV. Ergot, coarse powder av.oz. 8 Distilled water fl.oz. 3^/2 Alcohol sufficient Mix the drug with 15^2 fluidounces of distilled water, pack in a percolator, macerate for 12 hours, then allow the liquid to drain off, heat the percolate on a water bath until flocculent matter separates, and filter. Through the drug slowly pass the remainder of the water, evaporate this percolate to syrupy con- sistence, mix with the preceding evap- orated liquid, and to this mixture add 3 times its volume of alcohol, set aside for 24 hours, agitating frequently, filter, and evaporate on a water bath to thick extract. — Austr. Pharm. Extract, Fluid, of Ergot. I. Prepare according to the general proc- ess (see Extracts, Fluid), but moisten- ing 16^4 av.ounces of drug with 5 fluid- ounces of menstruum, and collecting the first 13^2 fluidounces that passes the percolator as the reserve percolate. The drug should be freshly ground. The menstruum for 16^ av.ounces of drug is 2 x / 2 fluidrams of acetic acid (36 per cent.) mixed with 13^ fluidounces of diluted alcohol, to be followed by di- luted alcohol. The weak percolate is to be evaporated at a temperature not above 50 deg. C. — U. S. P. II. Brit. Pharm. formula for liquid ex- tract of ergot: Ergot, crushed av.oz. 16^4 Distilled water fl.oz. 120 Alcohol fl.oz. 6 Digest the ergot with 80 fluidounces of the water for 12 hours, decant the liquid, repeat the digestion with the re- mainder of the water, express the liquid, mix the two liquids, evaporate them to 11^4 fluidounces, add the alcohol, set aside for an hour, and filter. III. Ergot, coarse powder av.oz. 16 Hydrochloric acid fl.dr. 3 Alcohol, distilled water, each sufficient Moisten the drug with a mixture of 3 fluidrams of alcohol and 10 fluidrams of water, pack in a percolator, and per- colate with a mixture of 3 volumes of alcohol and 10 of water, to exhaustion. Reserve the first 13^ av.ounces of per- colate, mix the weak percolate with the acid, evaporate it to a soft extract. Mix the reserve with the soft extract and add enough menstruum to make the product weigh 16 av.ounces. — Germ. Pharm. IV. Another preparation highly de- sirable for hypodermic use is the fol- lowing (Hallberg's formula) : "Purified ergot" is digested with twice its weight of water at 65 deg. C., for 24 hours and expressed ; the residue is again macerated in warm water for 12 hours. After settling, the expressed liquids are strained and evaporated sep- arately; when both together weigh one- half as much as the ergot employed, they are mixed and sufficient alcohol added to make the liquid of 25 per cent, alco- hclic strength, or one-third as much as the aqueous solution. After standing for several hours, the liquid is filtered and the gummy residue washed with so much 25 per cent, alcohol (4 volumes of alcohol and 11 of distilled water) as to make the filtered liquid measure three-fourths or 75 per cent, of the amount of crude drug employed (vol- ume for weight). To this glycerin is added to make the finished preparation represent the amount of crude drug er- got originally used, pint for pound. This preparation should be kept in small well-filled bottles in a cool, dark place. Purified ergot used for this prepara- tion may be made by percolating coarse- ly powdered ergot with deodorized ben- zine, until no more fatty matter is ex- tracted, then passing alcohol through the PHARMACEUTICAL PREPARATIONS. 151 drug until all the benzine is displaced, and then spreading the extracted drug out in thin layers and allowing it to remain exposed until perfectly dry and free from the odor of alcohol and ben- zine. Such a prepared ergot will keep in- definitely. Extract, Fluid, of Eucalyptus. Prepare according to the general proc- ess (see Extracts, Fluid), but using the drug in No. 40 powder, reserving the first 14^2 fluidounces of percolate ob- tained from 16^4 av.ounces of drug, and evaporating the remainder on a water bath at not above 50 deg. C. The men- struum is a mixture of 3 volumes of alcohol and 1 of water. — U. S. P. Extract, Fluid, of Euphorbia Pilu- lifera. The drug should be in No. 40 powder and should be extracted by Process A. The menstruum should be diluted alco- hol.— N. F. Extract, Fluid, of False Damiana. (Fluid Extract of Aplopappus.) Extract the leaves in very fine pow- der by any suitable process for fluid ex- tracts, using alcohol as the menstruum. ^Extract, Fluid, of Frostwort. (Fluid Extract of Helianthemum.) From the herb of Helianthemum cana- dense. Prepare according to Process A (see Extracts, Fluid), using the drug in No. 40 powder and diluted alcohol as the menstruum. — N. F. Extract, Fluid, of Galega. Drug in No. 30 powder, using Pro- cess A. for extraction. The menstruum should be diluted alcohol. — N. F. Extract, Fluid, of Gelsemium. Prepare according to the general proc- ess (see Extracts, Fluid), but moisten- ing 16^4 av.ounces of drug with 5 fluid- ounces of menstruum, reserving the first 14^} fluidounces of percolate, and evap- orating the remainder on a water bath. The menstruum is alcohol.— U. S. P. Extract of Gentian. I. Gentian, No. 20 powder. . .av.oz. 16 Water sufficient Moisten the powder with 6 l / 2 fluid- ounces of water, macerate for 24 hours, pack in a conical percolator, and gradu-. ally pour water upon it until the perco- late has but a slight bitter taste. Then reduce the liquid to three-fourths of its bulk by boiling, strain, and evaporate on a water bath to pilular consistence. — U. S. P. Commercial extract of gentian is made by boiling with water, the yield being greater, but a cold-prepared extract is superior. The extract of the Brit. Pharm. is made by infusing the drug with 10 times its weight of distilled water for 2 hours, boiling 15 minutes, straining, express- ing, and evaporating the liquid to soft extract. II. Gentian, cut into thin sha- vings av.oz. 16 Water fl.oz. 123 Alcohol fl.oz. i8>4 Macerate the drug with 77 fluidounces of water for 48 hours at a temperature of 15 to 20 deg. C., agitating occasion- ally, and express. Concentrate the liquid by evaporation; also macerate the resi- due in the same manner for 12 hours with 46 fluidounces of water, express, mix the two liquids, evaporate them to a weight of 48 av.ounces, when cold add the alcohol, set aside for 2 days in a cool place, filter, and evaporate the filtrate to thick extract. — Germ. Pharm. Extract, Fluid, of Gentian. Prepare according to the general proc- ess (see Extracts, Fluid), but using the drug in No. 30 powder, moistening i6^4 av.ounces of it with s x A fluidounces of menstruum, reserving the first 13 fluid- ounces of percolate, and evaporating the remainder on a water bath. The men- struum is diluted alcohol, — \J, S. P. 152 STANDARD FORMULARY OF Extract, Fluid, of Gentian, Com- pound. The article sold commercially under this title may be prepared as follows : Gentian av.oz. 10 Bitter orange peel av.oz. 4 Cardamom av.oz. 1 Alcohol, water, each, to make fl.oz. 16 Reduce the drugs together to mod- erately coarse powder, and extract by the usual process for making fluid extracts, so as to obtain 16 fluid- ounces of product, using as a men- struum a mixture of 3 volumes of alco- hol and 2 of water. The product is six times the strength of the official compound tincture, which latter may be prepared from it by mix- ing 1 fluidounce of it with 3 of alcohol and 2 of water. Extract, Fluid, of Gentiana Quinque- folia. Extract the root in moderately fine powder, by any suitable process for fluid extracts, using as a menstruum a mix- ture of 3 volumes of alcohol and 2 of water. Extract, Fluid, of Geranium. (Fluid Extract of Cranesbill.) Prepare according to the general proc- ess (see Extracts, Fluid), but using the drug in No. 30 powder, moistening i6}4 av.ounces of it with 5^2 fluidounces of menstruum, reserving the first 11H fluidounces of percolate, and evapora- ting the remainder on a water bath. The menstruum for 16^4 av.ounces of drug is a mixture of 13 fluidrams of glycerin, g l / 2 fluidounces of alcohol and 4H fluid- ounces of water, to be followed by a mixture of 3 volumes of alcohol and 2 of water. — N. F. Extract, Fluid, of Ginger. Prepare according to the general proc- ess (see Extracts, Fluid), but using the drug in No. 40 powder, moistening i6^4 av.ounces of it with 4 fluidounces of menstruum (alcohol), reserving the first 14^2 fluidounces of percolate, and evap- orating the remainder at not above 50 deg. C.-U. S. P. Extract of Golden Seal. (Extract of Hydrastis.) Exhaust golden seal in fine powder by any suitable process for extracts (see Extracts), using as a menstruum a mix- ture of alcohol and water in the propor- tion of 2 of the former to 1 of the latter by volume; then evaporate the tincture on a water bath to soft extract con- sistency. The alcohol may be recovered from the percolate by distillation. Extract, Fluid, of Golden Seal. (Fluid Extract of Hydrastis.) Prepare according to the general formula (see Extracts, Fluid), but moistening 16^4 av.ounces of drug with 5 fluidounces of menstruum, reserving the first 12 fluidounces of percolate, and evaporating the remainder on a water bath. The menstruum is a mixture of 13 fluidrams of glycerin with gY 2 fluid- ounces c: alcohol and 4^4 of water, to be followed by a mixture of 2 volumes of alcohol and 1 of water. The product is to be assayed and made to contain 2 grams of hydrastine in 100 cc. ; if it contains more than this proportion, a mixture of 2 volumes of alcohol and 1 of water should be added to reduce it to this standard. — U. S. P. The Germ. Pharm. directs a men- struum composed of 3 volumes of alco- hol and 1 of water, making 100 parts by weight of fluid extract from 100 parts of drug. The preparation of the Brit. Pharm. is made with diluted alcohol as the men- struum. Extract, Fluid, of Golden Seal, Aque- ous or Non-Alcoholic. The preparation which is sold under this name is generally prepared like the "glycerite of hydrastis" of the U. S. P. This is prepared according to the fol- lowing formulas : I. U. S. P.: Golden seal, fine powder. . .av.oz. 16^4 Glycerin fl.oz. 8 Alcohol, water, each sufficient Moisten the drug with 5^2 fluidounces of alcohol, pack it firmly in a percolator, PHARMACEUTICAL PREPARATIONS. 153 and percolate with alcohol until the hy- drastis is practically exhausted. To the percolate add 4 fluidounces of water, and then remove the alcohol by evap- oration or distillation. After the alco- hol is driven off, add enough water to the residue to make it measure 8 fluid- ounces, set it aside for 24 hours, then filter, pass enough water through the filter to make the filtrate measure 8 fluidounces, and, lastly, add the glycerin. II. Clark's process : Golden seal, fine powder. ..av.oz. 16^ Glycerin fl.oz. 8 Alcohol, water, each sufficient Exhaust the drug by percolation with a mixture of 9 volumes of alcohol and 1 of water. To the percolate add the glycerin and 4 fluidounces of water, and recover the alcohol by distillation. Let the residue stand for 2 days to separate resinous matter which deposits, decant the clear liquid, filter it, and add suffi- cient water to make the preparation measure 16 fluidounces. III. Lippincott's process : Golden seal, No. 40 powder.av.oz. 12 Distilled water fl.oz. 12 Glycerin fl.oz. 12 Alcohol fl.oz. 2 Mix the liquids, moisten the drug with 12 fluidounces, pack into a water-bath percolator, and the remaining liquid, heat the water bath and percolate to 88 deg. C. Reserve all the percolate, add to the drug twice successively 16 fluid- ounces of hot distilled water. Evaporate all of the latter percolate to a bulk that when mixed with the reserved liquid will make 16 fluidounces; mix and fil- ter. Extract, Fluid, of Golden Seal, Color- less. The prepartion which is sold under this title is the same as the "colorless solution of hydrastis." See Solution of Hydrastis, Colorless. Extract, Fluid, of Goldthread. (Fluid Extract of Coptis.) Prepare according to Process A (see Extracts, Fluid), using the drug in No. 40 powder, and diluted alcohol as the menstruum. — N. F. Extract, Fluid, of Green Osier. From the bark of Cornus circinata. Prepare according to Process A (see Extracts, Fluid), using the drug in No. 40 powder, and diluted alcohol as the menstruum. — N. F. Extract, Fluid, of Grindelia. Prepare according to the general proc- ess (see Extracts, Fluid), but using the drug in No. 30 powder, moistening i6^4 av.ounces of it with 5 fluidounces of menstruum, reserving the first 13J/2 fluidounces of percolate, and evapora- ting the remainder on a water bath. The menstruum is a mixture of 3 vol- umes of alcohol and 1 of water. — U. S. P. The liquid extract of grindelia of the Brit. Form, is made in the same man- ner, but using alcohol as the menstruum. This was also the menstruum of the U. S. P. 1890. Extract, Fluid, of Grindelia, Alka- line. Rother's formula: Grindelia, ground av.oz. 16^ Sodium bicarbonate gr. 240 Alcohol, water, each sufficient Moisten the drug with a mixture of 2 fluidounces of a mixture of 7 volumes of alcohol and 1 of water, pack in a percolator, and extract with the same menstruum to exhaustion. Distil the percolate to recover the alcohol, mix the dark-green residue with 8 fluid- ounces of water, and add the sodium bicarbonate gradually, stirring constant- ly. When the effervescence has nearly all subsided, warm the mixture gently, allow to cool, add water to make 12 fluidounces, filter, adding through the filter, if necessary, enough water to make 12 fluidounces of filtrate, and to the lat- ter add 4 fluidounces of alcohol. Extract, Fluid, of Guaiac. The so-called fluid extract of guaiac listed by manufacturers may be prepared as follows: 154 STANDARD FORMULARY OF Guaiac resin, coarse powd.. av.oz. & J /4 Alcohol, to make fl.oz. 16 Mix the resin with the alcohol in a wide-mouthed bottle, cork well, set aside for several days, in a warm place, agi- tating occasionally, until the resin is practically dissolved, then strain through muslin, and add enough alcohol through the strainer to make the liquid measure 16 fluidounces. This is 2 l / 2 times the strength of the U. S. P. tincture, which may be prepared from the above by mixing in the pro- portion of 2 fluidounces with 3 fluid- ounces of alcohol. Extract, Fluid, of Guarana. Prepare according to the general proc- ess (see Extracts, Fluid), but using the drug in No. 80 powder, moistening i6$4 av.ounces of it with zV\ fluid- ounces of menstruum, reserving the first wVz fluidounces of percolate and evaporating the remainder on a water bath. The menstruum is diluted alcohol. The product is to be assayed and made to contain 3.5 grams of alkaloids in 100 cc. ; if it contains more than this pro- portion, enough diluted alcohol should be added to reduce it to this standard. — U. S. P. Extract of Hemlock Spruce, Non- Alcoholic. (Concentrated Extract or Fluid Extract of Pinus Can- adenis.) The following corresponds in strength to that claimed for commercial prepara- tions : Pinus Canadensis, No. 40 powder av.oz. 32 Water, alcohol, each sufficient Glycerin fl.oz. 8 Mix 1 volume of alcohol with 2 of water, and exhaust the drug by the proc- ess of percolation. Distil the alcohol from the percolate, evaporate the re- maining liquid to 8 fluidounces, and to the residue add the glycerin. Extract, Fluid, of Hemlock Spruce. (Fluid Extract of Pinus Cana- densis.) Hemlock spruce bark, coarse powder av.oz. i6)4 Diluted alcohol , sufficient Extract in the usual manner for fluid extracts (see Extracts, Fluid), reserv- ing the first 14 fluidounces of percolate. Extract of Henbane. (Extract of Hy- oscyamus.) Evaporate fluid extract of henbane in a porcelain dish by means of a water bath at a temperature not exceeding 50 deg. C., constantly stirring, until re- duced to pilular consistence. This extract is to be assayed and is to contain 3 per cent, of mydriatic alka- loids. If the extract should be found to contain more than this percentage, enough powdered sugar of milk should be added to reduce it to this standard. — U. S. P. The Brit. Pharm. recognizes an Ex- tract of Henbane, Green, which see. The extract of henbane of the Germ. Pharm. is prepared like extract of bella- donna, which see. Extract of Henbane, Green. Prepare like Extract of Belladonna, Green (which see), from the fresh leaves, flowering tops and young branch- es of the plant. — Brit. Pharm. Extract, Fluid, of Henbane. (Fluid Extract of Hyoscyamus.) Prepare according to the general proc- ess (see Extracts, Fluid), reserving the first 13 fluidounces of percolate obtained from i6^4 av.ounces of drug. The men- struum is a mixture of 2 volumes of alcohol and 1 of water. The weak per- colate is to be evaporated at not above 50 deg. C. The product is to be assayed and made to contain 0.075 gram mydri- atic alkaloids in 100 cc. ; if it contains more than this proportion, enough of a mixture of 2 volumes of alcohol and 1 of water, should be added to it to reduce it to this standard.— U. S. P. Extract, Fluid, of Hops. Prepare according to Process A (see Extracts, Fluid), using the drug in No. 20 powder, and a mixture of 5 volumes of alcohol with 3 of water as the men- struum. — N, F, PHARMACEUTICAL PREPARATIONS. 155 Extract, Fluid, of Horehound, Com- pound. Horehound av.oz. 8H Comf rey av.oz. 4% Senega av.oz. 2}/% Wild cherry * av.oz. 2^8 Alcohol, water, each sufficient Mix the drugs, reduce to moderately coarse powder, and extract in the usual manner for fluid extract (see Extracts, Fluid), using a mixture of 1 volume of alcohol and 3 of water as the men- struum. Extract, Fluid, of Hydrangea. (Fluid Extract of Seven Barks.) From the root of Hydrangea arbores- cens. Prepare according to Process A (see Extracts, Fluid), using the drug in No. 60 powder, and a mixture of 3 volumes of alcohol and 2 of water as the men- struum. — N. F. Extract of Ignatia (Extract of St. Ignatius' Bean.) Procter's process : St. Ignatius' beans av.lb. 1 Water, alcohol, each sufficient Bruise the drug in an iron mortar until reduced to small fragments or very coarse powder, moisten with water in a covered vessel and apply heat cau- tiously until the tissues of the drug be- come soft and can be reduced to a pulpy mass. Mix this mass with about twice its bulk of alcohol, macerate in a closed vessel, in a warm place, for 24 hours, then place in a percolator and percolate with alcohol until 10 to 12 pinte of percolate are obtained, or the drug is exhausted. Evaporate the per- colate to soft extract consistency. The yield is about 10 per cent. Extract, Fluid, of Ipecac. I. Prepare according to the general proc- ess (see Extracts, Fluid), but using the drug in No. 80 powder, moistening i6^i av.ounces of it with s J A fluidounces of menstruum, and reserving the first izVz fluidounces of percolate. The men- struum is a mixture of 3 volumes of alcohol and 1 of water, The weak per- colate is to be evaporated at not above 50 deg. C. The product is to be as- sayed and made to contain 175 grams of alkaloids in 100 cc. ; if it contains more than this proportion, enough of a mixture of 3 volumes of alcohol and 1 of water should be added to reduce it to this standard.— U. S. P. II. Brit. Pharm. formula for liquid ex- tract of ipecac : Ipecac, No. 20 powder av.oz. 15 Calcium hydrate (slaked lime) av.oz. 1^2 Alcohol sufficient Moisten the drug with s x A fluidounces of alcohol, pack firmly in a percolator, and saturate the drusr with alcohol. When the liquid begins to drop from the percolator, close the lower orifice, and set aside for 24 hours. Then per- colate slowly until the drug is exhaust- ed. Reserve the first I2J4 fluidounces of percolate, mix the calcium hydrate intimately with the marc, allow them to remain in contact for 24 hours, and then continue percolation as before until the drug is again exhausted. Recover the alcohol from the two weak percolates by distillation, and dissolve the extract obtained in the reserved portion of per- colate. Assay the liquid for alkaloids, and to it add enough alcohol to make a liquid extract containing not less than 2 nor more than 2.25 grams of alkaloids in 100 cc, or from 2 to 2^ gr. in no minims. Extract, Fluid, of Jaborandi. (Fluid Extract of Pilocarpus.) Prepare according to the general formula (see Extracts, Fluid), but using the drug in No. 40 powder, moistening i6^4 av.ounces of it with 5^ fluidounces of menstruum, and reserving the first 12 fluidounces of percolate. The men- struum is diluted alcohol. The weak percolate is to be evaporated at not above 50 deg. C. The product is to be assayed and made to contain 0.4 grams of alkaloids in 100 cc. ; if it contains more than this proportion, enough dilu- ted alcohol should be added to it to 156 STANDARD FORMULARY OF reduce it to this standard.— U. S. P. and Brit. Pharm. extract of Jalap. I. Prepare according to the general proc- ess (see Extracts), but moistening i av.pound of drug with s l / 2 fluidounces of menstruum, percolating to exhaustion and evaporating the percolate to pilular consistence on a water bath. The men- struum is alcohol.— N. F. and U. S. P. 1890. II. Jalap, coarse powder av.oz. 8 Alcohol fl.oz. 38 Distilled water fl.oz. 76 Macerate the drug with, the alcohol for 7 days, express, filter the liquid, and evaporate the nitrate to soft extract. Macerate the marc with the water for 4 hours, again express, strain through flannel, evaporate the colature to soft extract, add the other extract, and evap- orate the whole at a temperature not exceeding 60 deg. C. to a hard extract. — Brit. Pharm. Extract, Fluid, of Jalap. Prepare according to Process A (see Extracts, Fluid), using the drug in No. 60 powder, and alcohol as the men- struum. — N. F. Extract, Fluid, of Jamaica Dogwood. (Fluid Extract of Piscidia.) Jamaica dogwood, fine pow- der av.oz. 16^4 Glycerin fl.oz. 1*4 Alcohol, water, each sufficient Moisten the drug with a mixture of the glycerin and 4^2 fluidounces of al- cohol, pack in a percolator, and exhaust with a mixture of 3 volumes of alcohol and 1 of water. Reserve the first 13 fluidounces, evaporate the remainder to soft extract, dissolve this in the reserved portion, and add enough of the second menstruum used for extraction, to make the product measure 16 fluidounces. — D. modified. Extract, Fluid, of Juniper. (Fluid Extract of Juniper Berries.) Prepare according to Process A (see Extracts, Fluid), using the drug in No. 10 powder, and diluted alcohol as the menstruum. — N. F. Extract, Fluid, of Kava Kava. (Fluid Extract of Ava or Kava.) From the root of Piper methysticum. Prepare according to Process A (see Extracts, Fluid), using the drug in No. 40 powder, and a mixture of 3 volumes of alcohol and 2 of water as the men- struum. — N. F. Extract of Kola. Kola, coarse powder av.oz. 8 Alcohol, distilled water, . each sufficient Macerate the drug with a mixture of 28 fluidounces of alcohol and 11 ^ of water for 2 days and express. Macerate the residue w T ith 185^ fluidounces of al- cohol and yy 2 of water for 2 days and again express. Mix the two liquids, filter, and evaporate the filtrate on a water bath to dryness. — D. The yield is about 8 or 8^ per cent. Extract, Fluid, of Kola. (Fluid Ex- tract of Sterculia — Liquid Ex- tract of Kola.) I. Prepare according to Process B (see Extracts, Fluid), using the drug in No. 20 powder, a mixture of 1 fluid- ounce of glycerin, 4 of alcohol and 11 of water being the first menstruum (for 16^ av. ounces of drug), and a mixture of 1 volume of alcohol and 3 of water the second menstruum. — N. F. II. Exhaust the drug in No. 40 pow- der by percolation with a mixture of 9 volumes of alcohol and 5 of water, using 1634 av.ounces of drug to make 16 fluid- ounces of product, and setting the first iT,y 2 fluidounces of liquid aside as the reserve percolate. — Brit. Form. Extract, Fluid, of Kousso or Cusso. (Fluid Extract of Brayera U. S. P. 1880.) Prepare according to the general proc- ess (see Extracts, Fluid), but using the drug in No. 40 powder. The menstruum is alcohol.— U, 3. P, 1890. PHARMACEUTICAL PREPARATIONS. 157 Extract, Fluid, of Lactucarium. Lactucarium (German or English preferred) coarse pieces av.oz. 4Y Stronger ether fl.oz. 5 Alcohol, water, each sufficient Add the lactucarium to the ether con- tained in a tared flask having the ca- pacity of 24 fluidounces, and let it mac- erate for 24 hours ; then add 12 fluid- ounces of water, and shake the mixture well. Fit a bent glass tube into the neck of the flask, and, having immersed the flask in hot water, recover the ether by distillation. When all the ether has distilled over, remove the tube, and, aft- er thoroughly shaking the contents of the flask, continue the heat for Y2 hour. Let the mixture cool, add 4Y av. ounces (5 fluidounces) of alcohol, and enough water to make the whole mixture weigh 20 av.ounces ; after maceration for 24 hours, with occasional agitation, express and filter the liquid. Return the dregs to the flask and macerate them with %Y\ av.ounces of a mixture of alcohol and water made in the proportion of 1 part of alcohol to 3 of water by weight ; re- peat the maceration 2 or 3 times, suc- cessively, with fresh portions of the mixture, until the dregs are tasteless, or nearly so. Mix, and filter the liquids thus obtained, and concentrate them, by means of a water bath (the first ex- pressed liquid by itself), until the com- bined weight of the liquids is 2.Y2 av.- ounces : mix the liquids, add 1^4 av.- ounces of alcohol, and let the mixture cool in the evaporating vessel, stirring the mixture frequently, and during the intervals keeping the vessel well cov- ered. When cool, add enough alcohol to make the mixture weigh 4Y av.- ounces, transfer the liquid to a flask, and add enough water to make the mixture measure 4 fluidounces, using the water so required to rinse the evaporating ves- sel. Shake the mixture occasionally, during several hours (and frequently, if a portion of the precipitate is found to be tenacious), and when a uniform mixture results, set it aside for 24 hours, so that any precipitate formed may subside. Decant the clear liquid, transfer the precipitate to a filter, and, after thoroughly draining it into the decanted liquid, wash it with a mixture of alcohol and water made in the pro- portion of 3 parts of alcohol to 4 of water, by weight, until the washings pass tasteless. Concentrate the washings, by evaporation, to a syrupy consistence, mix with the decanted liquid, and add enough of the last-named mixture of alcohol and water to make the whole measure 4 fluidounces. Lastly, after 24 hours, having meanwhile shaken the fluid extract occasionally, filter it through paper. This preparation was recognized in the U. S. P. 1880, but was rejected in the U. S. P. 1890, which adopted instead a tincture of lactucarium, which see. The revised N. F. admitted all the dropped preparations of the U. S. P. 1880, the above included. Owing to the fact that the tincture of lactucarium is the supe- rior preparation, and that these prep- arations are used only for making the syrup of lactucarium, which is more readily and satisfactorily made from the tincture, it is the tincture onlv which should be recognized. Extract, Fluid, of Ladies' Slipper. (Fluid Extract of Cypripedium.) Prepare according to the general proc- ess (see Extracts, Fluid), but moisten- ing i6ji av.ounces of drug with 5Y2 fluidounces of menstruum, reserving the first 13Y2 fluidounces of menstruum, and evaporating the remainder on a water bath. The menstruum is diluted alcohol. — N. F. Extract, Fluid, of Lavender, Comp'd. The article sold commercially under this title may be prepared as follows : Cassia cinnamon av.oz. 2f4 Nutmeg gr. 580 Red saunders gr. 580 Clove gr. 200 Oil of lavender flowers. .. .fl.oz. 1 Oil of rosemarv fl.dr. 2 158 STANDARD FORMULARY OF Alcohol fl.OZ. 1 1 Water fl.oz. 4 Diluted alcohol sufficient Reduce the drugs to coarse powder ; add the oils to the alcohol, add the wa- ter and with this mixture extract the drugs by any suitable process for fluid extracts, so as to obtain 16 fluidounces of product, adding diluted alcohol, if necessary, to make up the requisite vol- ume. The product is 8 times the strength of the compound tincture, which latter may be prepared from it by mixing 2 fluidounces of it with 10 fluidounces of alcohol and 4 fluidounces of water. Extract of Licorice. (Succus or Ex- tractum Liquiritiae.) I. Prepare according to the general process (see Extracts), but using the drug (licorice root) in No. 20 powder, moistening 1 av. pound of it with 15 fluidounces of menstruum, percolating to exhaustion, evaporating the percolate in a tared porcelain dish, by means of a water bath, to pilular consistence and while the mass is still warm, incorpor- ating with it 5 per cent, of its weight of glycerin. The menstruum for 1 av. pound of drug is a mixture of 2}/ 2 fluid- ounces of ammonia water with 46 fluid- ounces of distilled water, the percola- tion to be continued with distilled water. -U. S. P. II. Extract of licorice, in sticks, Water, each sufficient Put a layer of well-washed rye-straw over the bottom of a keg or other suit- able tall vessel. Then put a single layer of sticks of extract, broken into coarse pieces, over it. Continue to put in alternate layers of straw and extract until the vessel is full, or the whole of the extract has been disposed of. Fill the vessel with cold water, and allow it to remain for 3 days. Then draw off the solution., which has formed, by means of a faucet, or siphon, or other- wise, refill the vessel with cold water, and proceed as before. Mix the several solutions obtained, allow any suspended matter to subside, decant the clear solu- tion, and strain the remainder without pressure. Finally evaporate the liquid on a water bath to the consistence of a pilular extract. Excelsior may be substituted for the straw. The addition of a small quantity of salicylic acid or formaldehyde solu- tion will prevent fermentation of the aqueous liquid. Glycerite of licorice, which see, is a better preparation than either of the above, is more easily prepared, and is more convenient to use. III. Licorice root, No. 20 pow- der av.oz. 16 Distilled water fl.oz. 77 Mix the drug with one-half of the water, macerate for 24 hours, strain, express, mix the marc with the re- mainder of the water, macerate for 6 hours, strain and express again, mix the two liquids, heat to 100 deg. C, strain through flannel, and evaporate to soft extract. — Brit. Pharm. IV. Licorice root, cut av.oz. 8 Distilled water sufficient Dry the livorice, reduce it to coarse powder, macerate with 24 fluidounces of water for 12 hours, and express; mix the residue with 16 fluidounces of hot water, macerate for one hour and again express. Mix the two liquids, add some filter paper pulp or scraps of filter paper, boil for not less than 15 minutes, removing the scum, and filter. This filtrate must be returned to the filter until it is absolutely clear. Then evaporate to the consistence of thick honey, set it aside in a cool place for two days, dissolve in 2 parts of water, filter again, and evaporate on a water bath to thick extract. — D. Inasmuch as the liquids obtained or produced in the manufacture of this preparation "sour" quite easily this ex- tract is best made during the cool sea- sons of the year, the different opera' PHARMACEUTICAL PREPARATIONS. 159 lions being performed as rapidly as pos- sible. The yield from Russian licorice is 35 to 38 per cent, from Spanish, 20 to 25 per cent V. Russian licorice, coarse powder av.oz. 8 Alcohol fl.oz. g Water sufficient Pour 40 fluidounces of cold water over the licorice, allow to stand for 4 hours, stirring frequently, and then ex- press. Extract the press cake with 24 fluidounces of boiling water and again express. Mix the two liquid extracts and at once. Evaporate to 4 av. ounces, and add to the solution while hot the alcohol, and allow to stand for 24 hours. Then filter through paper and from the filtrate dis- til off 5 fluidounces. Evaporate the residue to a medium thick extract. The extract is completely soluble in water. The yield is about " 18 to 20 per cent. It is necessary, particularly in summer, to perform the operation rapidly; by beginning at 6 in the morn- ing one can be ready by midday to go on with the evaporation and the alcohol can be added by evening. Extract of Licorice, Pure. See Extract of Licorice, No. I. Extract of Licorice, Purified. See Extract of Licorice, No. II. Extract, Fluid, of Licorice. Pour 6]/2 fluidounces of boiling water upon 16^ av. ounces of drug, in No. 20 powder, contained in a suitable ves- sel and allow it to stand for an hour. Fack the moistened powder loosely in a metallic percolator, pour boiling water upon it, and allow percolation to pro- ceed, adding boiling water until the drug is exhausted. Evaporate the per- colate at a moderate heat until it meas- ures 7K fluidounces, when coo!, add 7 l A fluidounces of alcohol, mix well, and set aside for 3 days. After filter- ing the liquid, distil it until 8 fluid- ounces of distillate have been obtained; transfer the liquid in the still to a suit- able container, add 4 fluidounces of glycerin, 6}£ fluidrams of amm nia water, 2>Va fluidounces of alcohol, and enough water to make 16 fluidounces. — U. S. P. II. Brit. Pharm. for liquid extract of licorice : Licorice root, No. 20 pow- der ....av.oz 16 Distilled water fl.oz. 77 Alcohol sufficient Mix the drug with half of the water, macerate for 24 hours, strain and ex- press, mix the marc with the remainder of the water, macerate for 6 hours, again strain and express, mix the two liquids, heat to 100 deg. C, strain through flannel, evaporate the colature until it has a sp. gr., when cold, of 1.200, add to this one-fourth of its vol- ume of alcohol, let the mixture stand 12 hours, and filter. Extract, Fluid, of Lily-of-the-Val- ley Flowers. (Fluid Extract of Convallaria Flowers.) Prepare according to Process A (see Extracts, Fluid), using the drug in No. 40 powder, and diluted alcohol as the menstruum. — N. F. Extract, Fluid, of Lily-of-the-Val- ley Root. (Fluid Extract of Convalliara.) Prepare according to the general proc- ess (see Extracts, Fluid), reserving the first 13 fluidounces of percolate (from 16M av. ounces of drug), and evaporat- ing the remainder on a water bath. The menstruum is a mixture of 13 volumes of alcohol and 7 of water. — N. F. Extracts, Liquid. A class of preparations by the name of "liquid extracts" are recognized by the British Pharmacopeia and British Formulary. These are, in general, of the same strength as the fluid extracts of this country, and such of the liquid extracts as are recognized in this for- 160 STANDARD FORMULARY OF miliary are mentioned under the title of "fluid extracts." Sometimes the so-called "fluid ex- tracts" of resinous bodies, myrrh, ben- zoin, etc., which are really concentrated tinctures, are called "liquid extracts." Extract, Fluid, of Lobelia. Extract the drug, in Xo. 50 powder, by the usual process (see Extracts, Fluid), but moistening i6^4 av. ounces of drug (the herb), in No. 50 powder, with S l A fluidounces, reserving the first 14J/2 fluidounces of percolate, and evap- orating the remainder at not above 50 deg. C. The menstruum is a mixture of 11 volumes of 36 per cent, acetic acid with 29 of water. — U. S. P. The preparation of the U. S. P. 1890 was made with diluted alcohol. Extract, Fluid, of Lobelia, Comp'd. Lobelia seed av.oz. 4^ Lobelia herb av.oz. 4^ Blood root av.oz. 4^4 Skunk cabbage root av.oz. 4^ Diluted alcohol, to make. . .fl.oz. 16 Exhaust the mixed drugs in powder by any suitable process for fluid ex- tracts (see Extracts, Fluid). Most manufacturers make this preparation with S}/ 2 av. ounces of lobelia herb in- stead of herb and seed mixed — Eclectic. Extract of Logwood. Logwood, rasped av.oz. 16 Water pints 9^4 Macerate the logwood with the water for 48 hours, then boil (avoiding the use of metallic vessels) until about one- half the water has evaporated, then strain the liquid while hot, and evapor- ate to dryness. A suitable vessel for boiling- is an enameled-iron dish, providing the enamel be unbroken. This extract is not to be confused with the commercial extract which is decidedly inferior to the above for medicinal purposes. — U. S. P. Extract, Fluid, of Logwood. (Liquid Extract of Logwood.) Logwood, unfermented, Xo. 16 powder av.oz. 16^ Alcohol fl.or. 2 T / 2 Distilled water pints 6 Boil the logwood with 2 pints of the water in a covered copper or enameled pan for l / 2 hour, strain, boil the residue, with another 2 pints of the water for J / 2 hour, strain, and boil the residue again as before with the remainder of the water, and again strain, mix the three liquids, evaporate over a water bath (or preferably in a vacuum appara- tus) until the product measures 13^2 fluidounces, add the alcohol, set aside for 7 days, and then decant or siphon off the clear liquid from any sediment which may have deposited. — Brit. Form. Extract of Lupulin. Lupulin Alcohol .av.oz. 4 sufficient Place the drug loosely in a percolator, cover it with alcohol, allow to stand for 1 hour, then gradual!}- add alcohol until 32 fluidounces of percolate are obtained or the drug is practically exhausted. Evaporate the percolate on a water bath to soft extract consistency. Extract, Fluid, of Lupulin. Prepare according to the general proc- ess (see Extracts, Fluid), but packing the drug in the percolator without the preliminary moistening. The reserve percolate from i6}i av. ounces of drug is 14^2 fluidounces ; the menstruum is alcohol. The drug is to be used in its ordinary commercial condition, without further comminution. The drug is packed dry in the percolator because of its large proportion of extractive mat- ter.— N. F. Extract of Malt. (Extractum Byni.) I. -Malt, coarse powder, not finer than No. 12 av.oz. 67 Water gal. 2 l / 2 Upon the powder, contained in a suitable vessel, pour J / 2 gallon of water (not warmed), and macerate for 6 hours. Then add 2 gallons of water, heated to about 30 deg. C, and digest for an hour at a temperature not ex- ceeding 55 deg. C. Strain the mixture PHARMACEUTICAL PREPARATIONS. 161 with strong expression. Finally, by means of a water bath, or vacuum ap- paratus, at a temperature not exceed- ing 55 deg. C. evaporate the strained liquid rapidly to the consistence of thick honey. Keep the product in well-closed ves- sels, in a cool place. — U. S. P. and N. The above is Liebig's process for ex- tract of malt. There are also other ex- tracts of malt on the market, such as the numerous liquid extracts which are merely strong beers variously flavored. There is also a fluid extract of malt which is recognized by the former edi- tion of the N. F. Dry extract of malt is also to be had which is made by evap- orating the thick (the above) extract of nalt. The commercial brands of extract of malt vary greatly in quality; some of them are grossly adulaterated with glu- cose. II. Barley malt, freshly crushed av.lbs. 4 Water pints 22 Into a suitable vessel pour the water previously heated to 65 deg. C, add the malt, constantly stirring meanwhile, macerate for 2 hours, draw off the liquid, and evaporate this in a vacuum apparatus at a temperature not exceed- ing 55 deg. C. to the consistence of thick honey. The product is to be assayed. — Brit. Form. This process is practically the same as the preceding. III. Mattison's process: The quantities given here are such as would be used upon a tolerably large scale; these may, of course, be reduced as desired. Use a tube or churn of a capacity of 5 gallons and having a perforated^false bottom. Pour into it 3 l / 2 gallons of water of a temperature of about 76 to 78 deg. C, then add y 2 peck of barley malt, coarsely ground, gradually stir- ring it in well. Cover the vessel and set away in a warm place, and allow to remain perfectly at rest for 3 or 4 hours, taking care that the tempera- ture does not fall below 65 deg. C. This is the process of mashing. At the end of the allotted period of time, open the stop-cock below, draw off the fluid; now sprinkle over the top of the malt some water a little above the temperature of the extract, and draw off the fluid below, until the malt is practically exhausted. Evaporate the fluid by means of a water bath to thick consistence. The tub or churn must be kept per- fectly clean. Once a week it should be washed with alkaline water and when not in use it should be keot filled with lime water. Extract, Fluid, of Malt. Malt av.bz. 16 Alcohol, water, each sufficient Reduce the malt to coarse powder, not finer than No. 20. Moisten it with 7 J / 2 fluidounces of a^ mixture of 1 vol- ume of alcohol and- 3 volumes of water, and set it aside, well-covered, until it has ceased to swell. Then mix it with as much of the menstruum as it will take up without dripping, pack it uni- formly, but without pressure, in a per- colator, and add enough of the before- mentioned menstruum to cover it. When the liquid begins to drop from the ori- fice, close the latter, and allow the con- tents to macerate during 24 hours, add- ing from time to time more mens- truum, if necessary, to keep the malt just covered. Then remove the cork and allow the percolation to proceed until the percolate weighs 12 av. ounces. Set this aside, well-corked, until any susnended matters have been deposited. Then decant the clear liquid and pre- serve it for use. The product thus obtained may be re- garded as being practically equivalent to the drug in the proportion of minim for grain, the apparent excess of dis- solved matters present in the first por- tions of the percolate being about offset 162 STANDARD FORMULARY OF by the soluble matters still remaining in the drug, when the percolation is interrupted.— N. F. III. Extract of Malt with Alteratives. Calcium bromid gr. 160 Sodium bromid gr. 96 Potassium iodid gr. 160 Water, hot fl.oz. 1 Extract of malt, to make, .fl.oz. 16 Dissolve the salts in the water, and add to the extract. Extract of Malt with Beef. Extract of beef, Liebig's. ..av.oz. y 2 Water fl.oz. 1 Extract of malt, to make. . .fl.oz. 16 Dissolve the extract of beef in the water and mix the malt extract. Extract of Malt with Beef, Wine and Iron. Extract of malt fl.oz. 8 Beef, wine and iron fl.oz. 8 Extract of Malt with Cascara Sag- rada. Fluid extract of cascara sagrada fl.oz. 2 Extract of malt fl.oz. 14 It is best to use the bitterless fluid extract of cascara sagrada. Each tablespoonful represents 30 gr. of cascara sagrada. Extract of Malt with Cod Liver Oil. (Emulsion of Cod Liver Oil with Malt — Malted Emulsion of Cod Liver Oil.) I. Cod liver oil fl.oz. 5 Tragacanth, po gr. 23 Water fl.oz. iy 2 Extract of malt, to make fl.oz. 16 Mix the oil and tragacanth thoroughly in a bottle, add the water, and shake the mixture until a homogeneous suspension is formed. Finaly add the extract of malt in portions, shaking the mixture thoroughly after each addition until the finished product measures 16 fluid ounces. — N. F. IT. Cod liver oil fl.oz. 3 Extract of malt fl.oz. 17 Warm the extract to 45 deg. C. pour into a warm mortar, and incorporate the oil gradually and with constant trituration. — Brit. Form. III. Cod liver oil fl.oz. 8 Extract of malt fl.oz. 8 Yolk of two eggs, Tragacanth, powder gr. 15 Water, warm fl.dr. 4 Spirit of lemon drops 15 Spirit of bitter almond. .. .drops 15 Mix the extract with the warm water to thin it. - Beat yolks in a mortar with the tragacanth and add the oil and extract alternately, and lastly the spirits which latter may be varied to suit the taste. IV. Extract of malt fl.oz. 8 Cod liver oil fl.oz. 8 Oil of wintergreen drops 20 Oil of bitter almonds drops 5 Rub the cod liver oil verv gradually and thoroughly with the malt extract, then add the flavoring oils. If the mixture becomes too thick at any time, thin by the addition of a little water. It may be flavored in any other de- sired manner. V. Cod liver oil fl.oz. 8 Tragacanth, powder gr. 25 Extract of malt fl.oz. 6 Water fl.oz. 2 Triturate the gum with the malt ex- tract until well mixed, then add the oil gradually with uninterrupted trituration, and then add the water. VI. Commercial combinations of malt extract with cod liver oil usually contain only from 20 to 30 per cent, by volume of the oil instead of 38 to 50 per cent, as in the preceding. Malt extract is best combined with fixed oils by first warming it sufficiently to work easily as by using a warm mortar. Extract of Malt with Cod Liver Oil and Hypophosphites. Calcium hypophosphite gr. 64 Sodium hypophosphite gr. 48 Potassium hypophosphite. .. .gr. 32 Glycerin fl.oz. I PHARMACEUTICAL PREPARATIONS. 163 Water, hot fl.oz. I Extract of malt with cod liver oil fl.oz. 14 Triturate the hypophosphites to a fine powder, dissolve them as nearly as possible in the water and glycerin, and incorporate with malt extract and oil. Each tablespoonful contains 4^ gr. of the hypophosphites. Extract of Malt with Cod Liver Oil and Hypophosphites of Calcium. (Extract of Malt with Cod Liver Oil and Lime — Calcarated Ex- tract of Malt.) Extract of malt fl.oz. 8 Cod liver oil fl.oz. 4 Mucilage of dextrin fl.oz. 1 Calcium hypophospfiite gr. 192 Water fl.oz. 3 Mix the extract with the mucilage, add the oil gradually with constant tri- turation, then incorporate the water, having previously dissolved the hypo- phosphite in the latter. Each tablespoonful contains 6 gr. of the hypophosphite. Extract of Malt and Cod Liver Oil and Iodid of Iron. Extract of malt fl.oz. 8 Cod liver oil fl.oz. 4 Mucilage of dextrin fl.oz. 1 Syrup of iron citro-iodid. . .fl.oz. Yi Water fl.oz. 2^ Triturate the extract with the mucil- age, gradually add the oil with con- stantly stirring, and then incorporate the syrup and water. Each tablespoonful represents 1 gr. of tasteless iron iodid. Extract of Malt with Cod Liver Oil and Iron. (Ferrated Extract of Malt with Cod Liver Oil.) I. Cod liver oil fl.oz. 6 Extract of malt fl.oz. 6 Syrup -of soluble saccharat- ed iron fl.oz. 4 Add the oil gradually to the extract by trituration in a mortar until an emul- sion is formed, then add the syrup. II. Solution of dialyzed iron... fl. dr. s l A Extract of malt with cod liver oil, to make fl.oz. 16 Mix well by trituration. II III. Citrate of iron and am- monium gr. 64 Water, warm fl.dr. 4 Extract of malt with cod liver oil fl.oz. 15% Dissolve the iron salt in the water and incorporate this solution with malt extract and oil. IV. Iron phosphate, soluble gr. 64 Water, warm fl.dr. 4 Extract of malt with cod liver oil fl.oz. 15^2 Prepare like the preceding. V. Replace the iron phosphate in IV. with soluble iron pyrophosphate. Extract of Malt with Cod Liver Oil and Iron and Quinine Citrate. Extract of malt fl.oz. 8 Cod liver oil fl.oz. 4 Mucilage of dextrin fl.oz. 1 Iron and quinine citrate gr. 64 Water fl.oz. 3 Mix the extract with mucilage, add the oil gradually with constant tritura- tion, then incorporate the water, having previously dissolved the citrate in a portion of the water by the aid of a gentle heat. Each tablespoonful contains 2 gr. of iron and quinine citrate. Extract of Malt with Cod Liver Oil and Pancreatin. (Malt Extract with Pancreatized Cod Liver Oil.) I. Cod liver oil fl.oz. 6 Water fl.oz. 2 Extract of malt fl.oz. 8 Pancreatin, pure gr. 20 Sodium chlorid gr. 40 Sodium bicarbonate gr. 60 Oil of pimento sufficient Dissolve the pancreatin and two salts in the water, add the oil, and keep at a temperature of about 32 deg. C. for 3 hours, stirring occasionally. Put the malt extract in a mortar, add the pan- creatized oil gradually with constant stirring, and flavor the whole with oil of pimento (or other suitable flavor- ing). II. In this preparation, the oil is not 164 STANDARD FORMULARY OF first pancreatized as in the foregoing formula : Pancreatin, saccharated gr. 64 Extract of malt with cod liver oil fl.oz. 16 Triturate the pancreatin to fine pow- der, add a small portion of the extract with oil, mix well, and add the re- mainder. Extract of Malt with Cod Liver Oil, Pancreatin and Pepsin. Pancreatin, saccharated ....gr. 64 Pepsin, saccharated gr. 128 Extract of malt with cod liver oil fl.oz. 16 Triturate the pepsin and pancreatin together to fine powder, add a portion of the malt extract with oil, mix well, and add the remainder. Each tablespoonful contains 2 gr. of pancreatin and 4 of pepsin. Extract of Malt with Cod Liver Oil and Pepsin. Pepsin, saccharated gr. 128 Extract of malt with cod liver oil fl.oz. 16 Triturate the pepsin to fine powder, add a portion of the malt extract with oil, mix well, and add the remainder. Each tablespoonful contains 4 gr. of pepsin. Extract of Malt with Cod Liver Oil and Phosphorus. I. Phosphorus gr. 1 Cod liver oil fl.oz. 24 Extract of malt fl.oz. 24 Dissolve the phosphorus by the heat of a water bath in 4 fluidounces of the oil in a stoppered bottle, shake thor- oughly and when still warm incorporate the extract of malt, then add the re- mainder of the oil slowly to form an emulsion. II. Instead of using phosphorus as above, 100 minims of phosphorated oil may be employed, this latter to be add- ed to the cod liver oil, and this mix- ture then to be added to the extract of malt in the usual manner. III. Instead of using either free phosphorus or phosphorated oil, solu- tion of phosphorus N. F. may be em- ployed as according to the following : Solution of phosphorus. .. .fl.oz. 1 Extract of malt with cod liver oil fl.oz. 1 5 Mix well by trituration. Each tablespoonful contains about 1/100 gr. of phosphorus. Extract of Malt with Gentian and Iron Chlorid. Extract of malt fl.oz. 8 Elixir gentian and iron chlorid ....... fl.oz. 8 Extract of Malt and Hops. (Com- pound Extract of Malt — Some- times called Extract of Malt, plain.) I. Hops, fresh parti Malt parts 9 Water sufficient Make into an extract like extract of malt, which see. II. Fluid extract of hops fl.oz. y 2 Extract of malt fl.oz. 153/2 Mix well. Extract of Malt with Hypophos- phites. Calcium hypophosphite gr. 64 Sodium hypophosphite gr. 48 Potassium hypophosphite ....gr. 32 Water, hot fl.oz. 1 Glycerin fl.oz. 1 Extract of malt fl.oz. 14 Rub the salts in a mortar with the water until dissolved or nearly so, add the glycerin and finally the malt ex- tract. The above is also made to contain 32 gr. of iron hypophosphite. Each tablespoonful contains 4^2 gr. of hypophosphites. Extract of Malt with Hypophosphite of Calcium. (Extract of Malt with Lime — Calcarated Extract of Malt.) Calcium hypophosphite gr. 128 Water, hot fl.oz. 1 Glycerin fl.oz. 1 Extract of malt fl.oz. 14 Triturate the calcium salt to fine pow- der, dissolve as nearly as possible in the water and glycerin, and add the malt extract. PHARMACEUTICAL PREPARATIONS. 165 Each tablespoonful contains 4 gr. of hvoophosphite. Extract of Malt and Iron. (Ferrated Extract of Malt.) I. Iron pyrophosphate gr. 64 Water, warm fl.dr. 4 Extract of malt, to make. ..fl.oz. 16 Dissolve the iron salt in the water and incorporate the solution with the malt extract. This is the usual method of prepar- ing ferrated extract of malt. II. Solution of dialyzed iron. . .fl.dr. 5 J / 2 Extract of malt, to make ... fl.oz. 16 III. Citrate of iron and am- monium gr. 64 Water, warm fl.dr. 4 Extract of malt. fl.oz. 15^2 Dissolve the iron salt in the water and add the extract. IV. Instead of iron citrate in the last formula, soluble iron phosphate may be employed. V. Tincture of iron citro- chlorid fl.dr. 4 Extract of malt fl.oz. 15^ Extract of Malt with Iron and Qui- nine Citrate. Citrate of iron and quinine, .gr. 128 Water, warm fl.oz. 1 Extract of malt fl.oz. 15 Dissolve the iron and quinine salt in the water and incorporate with the malt extract. Each tablespoonful contains 4 gr. of iron and quinine citrate. See also Extract of Malt with Phos- phate of Iron and Quinine. Extract of Malt with Iron Iodid. Extract of malt fl.oz. 15^2 Syrup of iron citro-iodid. . .fl.oz. l / 2 Mix well. Each tablespoonful represents 1 gr. of tasteless iron iodid. Extract of Malt with Iron, Quinine and Strychnine Citrate. Strychnine sulfate gr. $/$ Distilled water, hot .fl.dr. Extract of malt with iron and quinine citrate, enough to make fl.oz. 16 Dissolve the strychnine salt in the water and incorporate this solution with the compound malt extract. Each tablespoonful contains 4 gr. of iron and quinine citrate and 1/50 gr. of strychnine sulfate. Extract of Malt with Pancreatin. Pancreatin, saccharated gr. 64 Extract of malt fl.oz. 16 Triturate the pancreatin and a small portion of the extract to a smooth paste and add the remainder of the ex- tract. Each tablespoonful contains 2 gr. of pancreatin. Extract of Malt with Pancreatin and Pepsin. Pancreatin, saccharated gr. 64 Pepsin, saccharated gr. 128 Simple syrup fl.oz. 1 Extract of malt, to make.. fl.oz. 16 Triturate the pepsin and pancreatin to a smooth paste with the syrup, then add the malt extract. Each tablespoonful contains 2 gr. of pancreatin and 4 of pepsin. Extract of Malt with Pepsin. Pepsin, pure gr. 64 Hydrochloric acid fl.dr. 1 Glycerin fl.oz. 1 Water fl.oz. 1 Extract of malt fl.oz. 14 Add the acid to the water and in this dissolve the pepsin, then add the glyc- erin and finally the malt extract. Each tablespoonful contains 2 gr. of pepsin. Extract of Malt with Phosphate of Iron and Quinine. Elixir of iron phosphate and quinine fl.oz. 8 Extract of malt fl.oz. 8 Mix well. See also Extract of Malt with Iron and Quinine Citrate. Extract of Malt with Phosphate of Iron, Quinine and Strychnine. Elixir of iron phosphate. quinine and strychnine. .. .fl.oz. 8 Extract of malt fl.oz. 8 166 STANDARD FORMULARY OF Extract of Malt with Syrup Phos- phates, Compound. Compound syrup of the phosphates fl.oz. 8 Extract of malt fl.oz. 8 Extract of Malt with Wine of Coca. Extract of malt fl.oz. 8 Wine of coca fl.oz. 8 Extract of Malt with Wine of Pep- sin. Extract of malt fl.oz 8 Wine of pepsin fl.oz. 8 Extract of Malt with Yerba Santa. Fluid extract of yerba santa fl.oz. i Solution of potassa fl.dr. 4 Extract of malt fl.oz. 14^ Mix the fluid extract with the solu- tion and incorporate the extract. Extract of Manaca, Fluid. Manaca root, fine powder. av.oz. i6^4 Glycerin fl.oz. 2 ^ Alcohol, water, each sufficient Moisten the drug with a mixture of the glycerin and zYa fluidounces of al- cohol, then pack in a percolator and exhaust by the usual process of perco- lation, using as a menstruum a mix- ture of 3 parts by volume of 'alcohol and 1 of water. Reserve the first 12 fluidounces of percolate, evaporate the weak percolate to 4 fluidounces and mix with the reserve percolate. — D. modified. Extract of Mandrake. ("Extract of May-Apple or Podophyllum.) Prepare according to the general proc- ess (see Extracts), using the drug in No. 60 powder and obtaining an ex- tract of pilular consistence. The mens- truum is a mixture of 4 volumes of alcohol and 1 of water. — N. F. Appen- dix and U. S. P. 1890. Extract, Fluid, of Mandrake. (Fluid Extract of May-Apple or Podo- phyllum.) Prepare according to the general proc- ess (see Extracts, Fluid), but moisten- ing i6^4 av. ounces of drug with 5 fluidounces of menstruum, reserving the first 13^2 fluidounces of percolate, and evaporating the remainder on a water bath. The menstruum is a mixture of 4 volumes of alcohol and 1 of water. — U. S. P. Extract, Fluid, of Mangifera. Mangifera bark, moderate- ly fine powder av.oz. 21 Glycerin fl.oz. 24 Water fl.oz. 72 Macerate the drug with the glycerin mixed with 40 fluidounces of water for 24 hours, strain with expression, mac- erate the residue with 32 fluidounces of water for 24 hours, strain again with expression, mix the two liquids, filter them, evaporate the filtrate on a water bath to 13 fluidounces, and to the latter add 3 fluidounces of alcohol. This drug is very difficult to extract ; the above is an easy process and fur- nishes a very good product. Extract, Fluid, of Matico. Prepare according to the general proc- ess (see Extracts, Fluid), but using the drug in No. 40 powder, moistening 16^4 av. ounces of it with 5 fluidounces of menstruum, reserving the first 13H fluidounces of percolate and evaporat- ing the remainder on a water bath. The menstruum is a mixture of 3 vol- umes of alcohol and 1 of water. — U. S. P. Extract of Mezereum. Make according to the general proc- ess (see Extracts), using alcohol as the menstruum. — U. S. P. 1880 and Germ. Pharm. (1st) modified. Extract, Fluid, of Mezereon. Prepare according to the general proc- ess (see Extracts, Fluid), but moisten- ing 1634 av. ounces of drug with 6 l / 2 fluidounces of menstruum, and reserving the first 14^2 fluidounces of percolate. The menstruum is a mixture of 4 vol- umes of alcohol and 1 of water. — N. F. Extract, Fluid, of Mullein. (Fluid Extract of Verbascum.) From the leaves and flowers of Ver- bascum Thapsus. Prepare according to Process A (see PHARMACEUTICAL PREPARATIONS. 167 Extracts, Fluid), using the drug in No. 20 powder, and diluted alcohol as the menstruum. — N. F. Extract, Fluid of Nettle Root, i^'iuid Extract of Urtica.) From the root of Urtica dioica. Prepare according to Process A (see Extracts, Fluid), using the drug in No. 40 powder, and diluted alcohol as the menstruum. Extract of Nux Vomica. (Extract- um Strychni.) I. Nux vomica, No. 20 pow- der av.oz. 16 Acetic acid, 36 p. c fl.oz. 8 Alcohol, water, and sugar of milk (dried and in fine -powder), each sufficient Mix the acid with 20 fluidounces of distilled water and having moistened the drug with 6 fluidounces of this menstruum, pack it moderately in a cylindrical glass percolator; then add enough menstruum to saturate the drug and leave a stratum above it. When the liquid begins to drop from the percolator, close the lower orifice, and, having closely covered the percola- tor, macerate for 48 hours. Then allow percolation to proceed slowly, gradually adding, first, the remainder of the mens- truum, and then water, until the per- colate passes but faintly imbued with bitterness and the drug is exhausted. Reserve the first 12 fluidounces of per- colate and having heated the remainder to boiling, filter, and evaporate the filtrate to soft extract; dissolve this in the reserved portion and add enough distilled water to make the liquid meas- ure 14 fluidounces. To the liquid thus obtained, add 46 fluidounces of alcohol, shake the mixture well, and set it aside for 24 hours, with occasional agitation. Filter the liquid through paper, and wash the residue in the filter with a mixture of 3 volumes of alcohol and 1 of water until the washings are only faintly bitter. Evaporate the filtrate and washings in a porcelain dish on a water bath to dryness. Assay the percentage of strychnine in this extract and add enough well-dried sugar of milk to bring the percentage of strychnine in the final dried extract down to 5 per cent, of the total weight. Reduce to fine powder, mix well, and keep in small, well-stoppered vials. — U. S. P. II. Sixteen fluidounces of liquid ex- tract of nux vomica is to be converted into 5 av. ounces of extract by distilling off the alcohol and adding sugar of milk. — Brit. Pharm. The product should contain 5 per cent, of strychnine. This extract has about 2-/3 the alka- loidal strength of the extract of the Brit. Pharm. 1885.— Brit. Pharm. III. Nux vomica, coarse pow- der av.oz. 16 Alcohol, water, each sufficient Macerate the drug with a mixture of 25^2 fluidounces of alcohol and Sy 2 of water for 24 hours at a temperature not exceeding 40 deg. C, agitating occa- sionally, express, macerate the residue in the same manner with a mixture of 19M2 fluidounces of alcohol and 6 l / 2 of water, again express, mix the two li- quids, let stand for several days, filter, and evaporate the filtrate to dryness. — Germ. Pharm. Extract, Fluid, of Nux Vomica. I. Nux vomica, No. 40 pow- der av.oz. i6^4 Acetic acid, 36 per cent fl.dr. 6*/ 2 Alcohol, water, each sufficient Mix the alcohol and water in the pro- portion of 3 volumes of the former to one of the latter. Moisten the drug with 16 fluidounces of this mixture to which the acetic acid has previously been added, and let it digest in a cov- ered vessel in a warm place for 48 hours. Then pack in a cylindrical glass percolator, and gradually pour mens- truum upon it until the drug is prac- tically exhausted, allowing percolation to take place slowly. Reserve the first 14^2 fluidounces of percolate, distil off 168 STANDARD FORMULARY OF the alcohol from the remainder by means of a water bath and evaporate the residue at a temperature not above 50 deg. C. to soft extract; dissolve this in the reserved portion, and mix thor- oughly. The product is to be assayed and made to contain 1 gram of strych- nine in 100 cc. ; if it contains more, enough menstruum should be added to it to reduce it to this standard. — U. S. P. II. Brit. Pharm. formula for liquid ex- tract of nux vomica : Nux vomica, No. 20 pow- der av.oz. 16 Alcohol, water, each sufficient Moisten the drug with 8 fluidounces of a mixture of 3 volumes of alcohol and 1 of water, set aside in a covered vessel for 6 hours, pack firmly in a percolator, and proceed further as in making a fluid extract or tincture, us- ing the above menstruum. Reserve the first 11^2 fluidounces of percolate, and continue percolation until 58 fluidounces more of percolate have been obtained. Express the marc and add the expres- sed liquid to the weak percolate. Re- cover the alcohol from this latter liquid by distillation, evaporate the residue to 1 fluidounce, add to this 3 fluidounces of alcohol, add this mixture to the re- served percolate, set aside for 24 hours, pour off the clear liquid, and filter the remainder. Determine the amount of strychnine in this filtrate, and to it add enough of a mixture of 3 volumes of alcohol and 1 of water so that every 100 cc. of product will contain 1.5 grams of strychnine, or every no minims i l / 2 grains. Extract of Opium. (Aqueous Ex- tract of Opium.) I. Opium, powder av.oz. 4 Sugar of milk, recently dried and in fine powder, Water, each sufficient Rub the opium in a mortar to a smooth paste with g J / 2 fluidounces of water, transfer to a bottle of the capac- ity of 40 fluidounces, wash the mortar with 28^2 fluidounces of water, in suc- cessive portions, and add the washings to the contents of the bottle. Cork the bottle and shake it vigorously once every 2 hours during 12 hours. Then filter through a rapidly-acting double filter and pour water slowly on the magma, until the filtrate passes nearly colorless and only faintly bitter. Evap- orate the filtrate and washings in a tared dish, on a water bath, until the contents weigh about 8 av. ounces, and allow the extract to become cold. Then assay it for morphine, and also deter- mine the proportion of moisture present by drying a small amount, in a flat-bot- tomed dish, at 100 deg. C, until it ceases to lose weight. Then add enough well-dried sugar of milk so as to bring the quantity of morphine in the final dry extract to 20 per cent, evaporate the whole to dryness, reduce it to pow- der, and transfer it to small, well-stop- pered vials.— II. Opium, sliced av.oz. 4 Distilled water fl.oz. 30 Macerate the opium with one-third of the water for 24 hours, express, mac- erate the residue with another third of the water for 24 hours, again express, macerate the residue with the remainder of the water for 24 hours, again ex- press, mix the three liquids, strain through flannel, and evaporate to 2 av. ounces. This extract should yield upon assay 20 per cent, of anhydrous morphine; if containing more, it should be diluted with" sufficient milk sugar. — Brit. Pharm. III. Opium, moderately fine powder av.oz. 4 Water fl.oz. 30 Macerate the drug with 20 fluidounces of water for 24 hours, agitating occa- sionally, express, macerate the residue with the remainder of the water for 24 hours, occasionally agitating, again ex- press, mix the two liquids, filter, and evaporate the filtrate to dryness. — Germ. Pharm. PHARMACEUTICAL PREPARATIONS. 16? Extract of Opium, Scale. I This preparation may be made in this manner : Exhaust opium, cut or broken into small pieces, by repeated digestion with warm water, evaporate the mixed in- fusions, by the aid of a gentle heat, to tolerably small bulk, allow to cool, agi- tate thoroughly with 2 or 3 times its volume of ether or purified benzin or gasolin, allow to stand for 24 hours, agitating occasionally, then decant the upper ethereal layer, pass the remain- ing liquid through filter paper, evapor- ate the filtrate on a water bath to syrupy consistence, spread or paint on glass or porcelain plates, and place in a warm location so that the extract may form into scales. II. Dyson's process : Deodorized tincture of opium fl.oz. 16 Acacia, powder gr. 120 Evaporate the tincture to 4 fluid- ounces, remove the vessel from the fire, add the gum and triturate thoroughly, replace the vessel on the fire, and con- tinue evaporation until the liquid is of such a density that it will have a syrupy consistence when cold. Now spread the liquid, while still warm, in thin layers on glass or porcelain plates and set aside to dry. Extract of Opium, for Smoking. The process given below is stated by Mr. John Calvert to be the actual method followed by the Chinese of San Francisco, arid presumably is the usual process, for preparing opium for smok- ing purposes. The apparatus of the Chinaman con- sists of two charcoal-burning fire-clay furnaces, about 15 inches high and of about the same width, open on three sides ; some palm leaf or other cheap fans for fanning himself and the fire ; sev- eral brass pans; a brass ladle and sev- eral tin ones ; a large spoon for skim- ming ; a gridiron, two pair of pincers for lifting the pans, and some thick wooden cloth to protect the hands, some fiber brushes, several buckets, basket strainers, muslin for straining, fibrous material for drawing off the liquor, some heavy sticks to be used as pestles, several spatulas, about a foot long and 3 inches wide at lower end, and made of oak or ash, and a steel- bladed scraper. One or two low stools complete the arrangements. The opera- tor does not require any tables or benches, as all the work is done on or near the ground. The operation re- quires two days, but after the first day, the two days' work goes on' regularly, and a batch of extract is turned out by the same workman every evening. The quantity of opium operated upon, so that a workman can do a fair day's work, is usually about 16 or 18 pounds. The balls are placed in tepid water, to soften the surface, and they are washed by hand to remove grit, leaves and other foreign substances. The material is then placed in one of the shallow concave brass pans, which is kept gently heated over the naked charcoal fire, and by means of the wooden pestle, is kneaded into a soft paste. When homo- geneous, the softened opium is uniform- ly spread over the inner surface of the pan, and pattecl down by the hand, so as to give it a smooth surface. The heat is continued until the greater part of the moisture has evaporated, and the opium has become so solid that the pan can be turned over. The direct heat of a very small fire is now allowed to act directly on the face of the opium by turning the pan upside down. This has to be carefully and skillfully done. As soon as the surface of the material has become sufficiently hardened, it is deftly removed in thin layers, and this is continued until all the opium has been taken from the pan, except the dried portion which remains attached to the bottom and sides of the vessel. This is scraped off. The crusts which were laid aside- in the former operation are now put on the gridiron, a few at a 170 STANDARD FORMULARY OF time, with the greatest care, to avoid breaking them, and are toasted over the charcoal at a low temperature until they have become perfectly crisp. The crusts are then placed in one of the brass pans, covered with warm water, and left standing until the next morning. On resuming work the infusion is first drawn off into buckets through baskets lined with muslin strainers. The brass pan is slightly tilted, and by means of a knot of vegetable fibre the liquor is drawn off over the edge of the pan without loss. The roasted opium is drained, and a second quan- tity of warm water added, with as lit- tle breakage of the crusts as possible, and the extraction is finished with a third lot of water. Only the first and second infusions are used for the ex- tract; the washings and weak infusion are employed for the extraction of the next batch. There seems to be no pre- cise rule as to the quantity of water for making the infusion, the crusts are merely covered. The infusion is then mixed with some egg albumen and a part of it is placed in the largest of the brass pans over the naked charcoal fire, and is heated, skimmed and boiled constantly. The pan is not filled, but room is allowed for frothing, and fresh portions of warm infusion containing albumen are added from time to time as the bulk diminishes. During the boiling there are several matters to be attended to, such as keeping up the fire, or banking it up with ashes if too hot, prevention of boiling over by addition of small quantities of the infusion, or of water, and keeping the sides of the pan free from hardened extract. This is effected by water and the fiber scrubbing brushes. When all the infusion has been added, and the evaporation has proceeded as far as is considered to be necessary, the pan is removed from the fire, and the extract constantly stirred by means of a wooden spatula in a current of air produced by fanning until cool and uni- formly mixed. The yield of extract varies according to the kind and quality of opium. Eighteen pounds of first quality opium generally ^ yield about ten pounds of this extract. The greatest watchfulness is exercised over the roasting or toasting nart of the process. Although a small exposed cor- ner of the crusts may become charred occasionally, the object of this operation is to expose the opium to such a heat only as to render it porous, to do away with the quality of stickiness, which is said by some authors to be produced by an easily decomposed caoutchouc-like substance, and to allow the aqueous ex- tractive matter to ooze out of the ma- terial without stirring. Extract of Opium, Liquid. Extract of opium of the Brit. Pharm gr. 256 Distilled water fl.oz. 12 Alcohol fl.oz. 3 Macerate the extract in water for an hour, stirring frequently, then add the alcohol, set aside for 24 hours, in a cool place, and filter. — Brit. Pharm. If the U. S. P. extract be employed 284 gr. of it will be required. Extract, Fluid, of Opium, Camphor^ ated. (Concentrated Paraegoric.) Opium, fine powder gr. 240 Benzoic acid gr. 240 Camphor gr .240 Oil of anise fl.dr. 4 Alcohol fl.oz. 12 Water fl.oz. 3 Dissolve the camphor, oil and acid in the alcohol, triturate the opium to a smooth paste with the water, mix the two liquids, macerate for 7 days, agi- tating frequently, and filter. This is similar to the "convenience" preparations put up by manufacturers which may be used for making pare- goric, being 8 times stronger than the latter. To make the latter mix 2 fluid- ounces of the concentrated preparation with 1 fluidounce of glycerin and 13 fluidounces of diluted alcohol. PHARMACEUTICAL PREPARATIONS. 171 Extract, Fluid, of Opium, Deodor- ized or Deodorized Aqueous. The article sold under this title is the deodorized tincture of opium of the U. S. P. Extract, Fluid, of Orange Peel. (Bitter.) Prepare according to the general proc- ess (see Extracts, Fluid), using the drug in No. 40 powder, moistening 16^. av. ounces of drug with $y 2 fluid- ounces of menstruum, packing in a coni- cal percolator, reserving the first 12^4 fluidounces of percolate and evaporat- ing the remainder at not above 50 deg. C. The menstruum is a mixture of 2 volumes of alcohol and 1 of water. — U. S. P. Extract, Fluid, of Pareira. I. Prepare according to the general process (see Extracts, Fluid), but using the drug in No. 40 powder, reserving the first i^A fluidounces of percolate received from 16% av. ounces of drug, and evaporating the remainder on a water bath. The menstruum for 16^4 av. ounces of drug is a mixture of 13 fluidrams of glycerin, 9^2 fluidounces of alcohol, and 4^4 fluidounces of water, to be followed by a mixture of 2 vol- umes of alcohol and 1 of water. — U. S. P. II. Brit. Pharm. formula for liquid ex- tract of pareira : Add to the drug, in No. 40 powder, rather more than equal weight of boil- ing distilled water, macerate for 24 hours, pack in a percolator, and pass through the drug boiling distilled water until the percolate amounts to about 10 times the weight of the drug used, or until the latter is exhausted. Ascer- tain the proportion of extractive matter in the percolate by evaporating a small portion on a water bath to a firm ex- tract. Then evaporate the total perco- late until it contains 1/3 of its weight of such extractive matter. To this liquid add 1/3 of its volume of alcohol. Filter, or otherwise clarify, if neces- sary. Extract, Fluid, of Parsley Root. Prepare according to Process A (see Extracts, Fluid), using the drug in No. 40 powder, and diluted alcohol as the menstruum. — N. F. Extract, Fluid, of Pink Root. Prepare according to the general proc- ess (see Extracts, Fluid), but moisten- ing 16^4 av. ounces of drug with 5 fluidounces of menstruum, reserving the first 13^2 fluidounces of percolate, and evaporating the remainder on a water bath. The menstruum is diluted alco- hol.— U. S. P. Extract, Fluid, of Pinkroot, Comp'd. (Fluid Extract of Entozoic Pow- der.) .av.oz. 3 , av.oz. 3 .av.oz. 3 .av.oz. 3 av.oz. $y 2 Pink root Swamp milkweed .... Mandrake Dogsbane Balmony Alcohol, water, each sufficient Mix the drugs, reduce to moderately fine powder, and exhaust by the usual process for fluid extracts (see Extracts, Fluid), using a mixture 3 volumes of alcohol and 1 of water as the mens- truum, and making 16 fluidounces of product. — Eclectic. Extract, Fluid, of Pink Root and Senna. Fluid extract of oink root..fl.oz. 10 Fluid extract of senna fl.oz. 6 Oil of anise m. 20 Oil of caraway m. 20 Mix the fluid extracts and dissolve the oils in the mixture. — U. S. P. 1870. In the U. S. P. i860 formula, 240 grains potassium carbonate was added to the above mixture. Many manufac- turing firms make this preparation with the alkaline admixture, sometimes how- ever adding but 120 grains. Extract, Fluid, of Pinus Canadensis. See Extract, Fluid, of Hemlock Spruce. 172 STANDARD FORMULARY OF Extract, Fluid, of Pipsissewa. (Fluid Extract of Chimaphila or Prince's Pine.) Prepare according to the general proc- ess (see Extracts, Fluid), but using the drug in No. 30 powder, receiving the first 11^2 fluidounces (from i6^4 av. ounces of drug) as reserve percolate, and evaporating the remainder on a water bath. The menstruum is diluted alcohol— U. S. P. Extract, Fluid, of Pleurisy Root. (Fluid Extract of Asclepias or Asclepias Tuberosa.) Prepare according to the general proc- ess (see Extracts, Fluid). The mens- truum is diluted alcohol. — N. F. and U. S. P. 1890. Extract, Fluid, of Poke Root. Prepare according to the general for- mula (see Extracts, Fluid), reserving the first 13 fluidounces of percolate from 16^4 av - ounces of drug. The mens- truum is diluted alcohol. — U. S. P. and N. F. (1st Ed.). Extract, Fluid, of Pomegranate. Prepare according to the general proc- ess (see Extracts, Fluid), but moisten- ing i6^4 av. ounces of drug, in No. 30 powder, with 6^2 fluidounces of mens- truum, and reserving the first 13 fluid- ounces. The menstruum is a mixture of 13 fluidrams of glycerin with 14^ fluidounces of diluted alcohol, to be fol- lowed by diluted alcohol. — U. S. P. Extracts, Powdered. Most extracts now appear on the market, not only in the old-style plastic or pilular form, but also in the form of powder. Inasmuch as almost all plant extracts are injured by the appli- cation of heat, the powdered extracts do not very well represent the drug, less so in fact than almost any prepara- tion made from a crude drug. How- ever, there is a demand for these pow- dered extracts, and this demand will be supplied. Extracts like those of opium and kino can be evaporated to dryness without any appreciable injury to the principles present, but others again, like hyostyamus, valerian, etc., are very sus- ceptible to change, either because of the presence of easily decomposable prin- ciples or because of the presence of volatile matter. These latter extracts should never be prepared in the pow- dered form. However, practically all extracts now appear in the market in the powder form, irrespective of the ap- propriateness, suitability or value fluidounces of water. The formula of the Brit. Pharm. is practically like that of the N. F., viz., 666 gr. of pepsin, 90 m. of hydrochloric acid, g l /2 fluidounces of glycerin, and water enough to make 16 fluidounces. The Brit. Pharm. pepsin should be ca- pable of dissolving 2,500 times its weight of coagulated egg albumen. Glycerite of Pepsin, Comp. (Glycer- ite of Pepsin and Wafer Ash.) Oleoresin of wafer ash gr. 120 Pepsin, scale gr. 64 Glycerin fl.oz. 16 — Eclectic modified. King's Dispensatory gives the above formula with 256 grains of "dry" pep- sin, but does .not describe what is meant by this term. Inasmuch as. the scale pepsins of the present-day market are of such excellent quality, the above mod- ified formula should be satisfactory. Glycerite of Phosphates of Iron, Quinine and Strychnine. Iron phosphate, scale gr. 290 Quinine, alkaloid gr. 380 Strychnine, alkaloid gr. 3 Phosphoric acid, S> p. c. . . .fl.dr. 13 Glycerin fl.oz. 4 Distilled water, to make. . .fl.oz. 8 Heat the iron salt with \ l / 2 fluidounces of distilled water in a porcelain di'sh at a temperature not exceeding 70 deg. C. until dissolved, then add the acid, qui- nine and strychnine, and enough dis- tilled water to make 4 fluidounces, and stir until solution is effected. Mix this with the glycerin and filter if necessary. — U. S. P. VIII. This preparation is used to make syr- up of phosphates of iron, quinine and strychnine. Glycerite of Potassium Bromid. Potassium bromid gr. 60 Glycerin gr. 300 Triturate together thoroughly. — Eclec- tic. Glycerite of Potassium Chlorate. (Glycerin Solution of Chlorate of Potassium.) Potassium chlorate, powder.. gr. 60 Glycerin gr. 600 Place together in a bottle and agitate. — Eclectic. Glycerite of Quinine Sulfate. (Glyc- erite of Quinine.) Quinine sulfate gr. 24 Glycerin fl.oz. 2 Triturate together until the quinine is dissolved. — Eclectic. Glycerite of Quinine Sulfate with Strychnine. (Glycerate of Qui- nine and Strychnine.) Strychnine gr. 1 Quinine sulfate gr. 40 Glycerin fl.oz. 4 Triturate together. — Eclectic. It is preferable, however, to use strychnine sulfate or some other soluble salt of strychnine instead of the alka- loid. Glycerite of Bhatany. Fluid extract of rhatany. .. .av.oz. 3 Glycerin av.oz. 1 Water av.oz. 1 Mix, evaporate the alcohol at the tem- perature of the water bath, and add water to the residue to make it weigh 3 av.ounces. This is used when the presence of al- cohol is considered objectionable. — Ec- lectic. Glycerite of Salicylic Acid. Salicvlic acid (from natural wintergreen oil) gr. 60 Borax, fine powder gr. 60 Glycerin fl.oz. 2 Triturate the acid with the borax un- til well mixed, then add the glycerin, PHARMACEUTICAL PREPARATIONS. 201 and rub until a clear solution is ob- tained. — Eclectic. Glycerite of Silver Nitrate. Silver nitrate, crystal gr. 80 Glycerin fl.oz. 1 Weaker preparations may be made by diluting this with glycerin or distilled water. — Eclectic. Glycerite of Sodium Sulfite. Sodium sulfite gr. 120 Glycerin fl.oz. 3 Triturate thoroughly together and transfer to a bottle. — Eclectic. Glycerite of Starch. (Glycerin Oint- ment — Plasma — Glycamyl — Glyceritum Amyli.) Cornstarch av.oz. 2 Water fl.oz. 2 Glycerin fl.oz. 12^4 or av.oz. 16 To the starch contained in a porcelain capsule add the water and glycerin, and stir until a homogeneous mixture is produced. Then apply heat gradually raised to 140 deg. C. and not exceeding 144 deg. C., stirring constantly, until a translucent jelly is formed. Transfer the product to suitable vessels provided with well-fitting covers. — U. S. P. It is advisable to rub the starch to a •smooth mixture with the water before adding glycerin. The addition of 1 to 2 grains of pow- dered tragacanth will prevent the sep- aration, on standing, of the starch from the glycerin. The preparation of the Brit. Pharm. is of the same strength as the above. II. The corresponding preparation of the 3rd Germ. Pharm., called Unguen- tum Glycerini, was prepared as follows: Wheat starch av.oz. 1 Tragacanth. fine powder gr. 90 Alcohol fl.dr. 5 Water fl.oz. i l / 2 Glycerin av.oz. 10 Triturate the starch to a smooth paste with the water, add the glycerin, then incorporate the tragacanth previously triturated to a smooth paste with the alcohol, and heat the whole with almost constant stirring until the alcohol has dissipated and a translucent jelly is pro- duced. The preparation of the last (4th) Germ. Pharm. is somewhat different, as follows : Wheat starch av.oz. 1 Water fl.oz. ij£ Glycerin av.oz. 10 Triturate the starch with the water to a smooth paste, incorporate the glyc- erin and heat the whole on a water bath with constant stirring until a translucent jelly is obtained. Glycerite of Tannic Acid. (Glycerite of Tannin.) Tannic acid av.oz. 4 Glycerin av.oz. 16 Triturate the acid with the glycerin to a smooth paste, transfer this to a porcelain dish, avoiding contact with metallic utensils, and apply the heat of a water bath until the acid is completely dissolved. Then transfer the solution to a bottle.— U. S. P. It is usually advisable to strain the solution, while still warm, through a piece of flannel or a pledget of cotton. Glycerite of Tar. Pine tar av.oz. 1 Magnesium carbonate av.oz. 2 Glycerin fl.oz. 4 Alcohol fl.oz. 2 Water, to make fl.oz. 16 Upon the tar, contained in a mortar, pour 3 fluidounces of cold water, stir them thoroughly together, and pour off the water. Repeat this once or twice, until the water only feebly reddens blue litmus-paper. Now triturate the washed tar with the alcohol, gradually incor- porate the magnesium carbonate and glycerin, and lastly, 10 fluidounces of water. Pour the mixture upon a filter of loose texture spread over a piece of straining muslin, and, after the liquid portion has passed through, wash the residue on the filter with water, until the whole filtrate measures 16 fluid- ounces.— N. F. and U. S. P. 1870. Regarding filters of loose texture, see Glycerite of Pepsin. An Eclectic preparation of the same name for external use is made by tritu- rating one part by weight of tar with 8 202 STANDARD FORMULARY OF parts by weight of glycerite of starch to a smooth paste. It is advisable to warm the glycerite of starch previous to the mixing. Glycerite of Tragacanth. Tragacanth, pure, fine pow- der av.oz. 2 Glycerin fl.oz. 12 Water fl.oz. 3 Triturate the trangacanth with the glycerin in a mortar, add the water, and continue the trituration, until a homo- geneous, thick paste results. — N. F. The preparation of the Brit. Pharm. is prepared by mixing 4% av.ounces of tragacanth with 12 fluidounces of glyc- erin in a mortar, adding 4 fluidounces of water, and triturating until a homo- geneous paste is formed. Glycerite of Veratrine. Veratrine (alkaloid) gr. 3 Glycerin gr. 297 Alcohol sufficient Dissolve the alkaloid in a small quan- tity of alcohol by triturating in a warm mortar, then gradually add the glycerin, and continue trituration in the warm mortar until the alcohol has evaporated. -^Eclectic. Glycerite of Yolk of Egg. (Glyconin Glyceritum Vitelli.) Yolk of egg, fresh av.oz. 9 Glycerin av.oz. 1 1 Or use equal parts by measure. Rub the yolk of egg in a mortar with the glycerin, gradually added, until they are well mixed.— N. F. and U. S. P. 1890. Glycerogelatins. Glycerogelatins are soft masses, melt- ing at the body temperature, composed of glycerin, gelatin, water and a medica- ment suitable for external application in dermatological practice, such as sali- cylic acid, iodoform, ichthyol, resorcin, chrysarobin, etc., either by themselves or with the addition of zinc oxid. They were originally suggested by Dr. Unna. The formulas given below serve as types. The added solid substance must be in very fine powder. — N. F. Glycerogelatin, Iodoform, 10 per cent. Glycerinated gelatin, U.S.P..parts 2 Glycerin parts 3 Distilled water parts 13 Iodoform, very fine powder. parts 2 Melt glycerinated gelatin on a water bath, at a gentle heat, add 10 parts of water and, continuing the heat, a pre- viously prepared mixture of the iodo- form, the glycerin and the remainder of the water. Mix well and immedi- ately pour the mixture into chilled molds or other suitable containers.— N. F. Glycerogelatin, Salicylic Acid, 10 per cent. Glycerinated gelatin, U.S. P.. .parts 4 Glycerin parts 7 Distilled water parts 7 Salicylic acid, very fine pow- der parts 2 Triturate the acid with the glycerin and water, add the mixture to the pre- viously melted glycerinated gelatin, con- tinuing the gentle heat of a water bath and stirring until a homogeneous mix- ture is effected. Then pour it into chilled molds or other suitable contain- ers. — N. F. Glycerogelatin, Zinc, Firm. Glycerinated gelatin, U.S. P.. parts 6 Glycerin parts 5 Distilled water parts 7 Zinc oxid parts 2 Melt the glycerinated gelatin on a wa- ter bath, at a gentle heat, add 2 parts of glycerin and the water, and, contin- uing the heat, the zinc oxid, previously finely levigated with the remainder of the glycerin. Mix thoroughly, and pour the mixture into chilled molds or other suitable containers. — N. F. Glycerogelatin, Zinc, Soft. Prepare like the preceding, but de- creasing the glycerinated gelatin to 4 parts and increasing the glycerin to 7 parts.— N. F. Granules. Granula — Kcerner. The German Pharmacopoeia gives a general formula for preparations of this name as follows : Triturate the substance, either as it is or in solution in ether, alcohol or water PHARMACEUTICAL PREPARATIONS. 203 with a suitable quantity of a powdery mixture composed of 4 parts of milk sugar and 1 part of acacia until inti- mately mixed, make a mass with simple syrup containing 10 per cent, of glyc- erin, and divide into the required num- ber of granules which are to be of spherical form. Each dry granule is to weigh 1/20 gram (& grain). Greases. Greases or fats, more properly termed lards, may be found under the latter designation. Honeys. (Mellita.) The preparations known as honeys are a diminishing class, their place being taken by the glycerites and syrups. They are prepared either by dissolving or mixing medicinal agents with honey. Honey, Clarified. (Mel Depuratum.) I. Mix honey intimately with about 2 per cent, of its v/eight of paper pulp which has previously been reduced to shreds, thoroughly washed and soaked in water strongly expressed, and again shredded. Then apply the heat of a water bath, and, as long as any scum rises to the surface, carefully remove this (with a skimmer). Then add enough distilled water to make up the loss by evapora- tion, strain, and mix the strained liquid with 5 per cent, of its weight of glyc- erin.-U. S. P. Filter paper should be used for ma- king paper pulp for the above. The shredding or reducing to pulp may be facilitated after moistening by vigor- ously triturating in a large mortar. II. The directions of the Brit. Pharm. for clarified honey are quite simple, viz. : Honey of commerce, melt- ed in a water bath, and strained, while hot, through flannel previously moist- ened with warm water. III. Honey av.oz. 16 Water fl.oz. 23 Heat together on a water bath for one hour, allow to cool to about 50 deg. G, strain through thick flannel, and evap- orate on a water bath until the liquid has a sp. gr. of 1.33. — Germ. Pharm. The honey used should be examined for acidity ; 10 grams should require not more than Y 2 cc. normal, or 5 cc. deci- normal, solution of potassium hydrate for neutralization. Honey of Borax. (Borax Honey- Mel Boracis.) I. Borax, powder av.oz. 2 Clarified honey av.oz. 16 Mix and dissolve by the aid of a gen- tle heat.— U. S. P. 1870. II. Borax, powder av.oz. 2 Glycerin av.oz. 1 Honey av.oz. 16 Prepare like the preceding. — Brit. Pharm. Honey of Rose. (Mel Rosae — Mel Rosatum or Rosarum.) I. Fluid extract of rose fl.oz. 2^2 Honey, clarified, to make the total weigh av.oz. 22 The product will measure approxi- mately 16 fluidounces. — U. S. P. II. Red rose petals, cut av.oz. 2 Glycerin av.oz. 2 Water fl.oz. 3 Alcohol fl.oz. 9 Clarified honey av.oz. 18 Mix the petals with the alcohol and water, macerate for 24 hours in a well- closed vessel, agitate frequently, express, filter, add the glycerin and honey, and evaporate the whole to the weight of 20 av.ounces. — Germ. Pharm. III. Red rose petals av.oz. 2 Water, boiling fl.oz. 24 Glycerin fl.oz. 3 Honey fl.oz. 12 Pour the water on the petals, let stand 24 hours, express, evaporate the cola- ture to about 1^2 fluidounces, and to this add the glycerin and honey. — H. modified. This is an excellent preparation and is very easily made. 204 Standard formulary of IV. Inspissated extract of rose.av.oz. y 2 Glycerin av.oz. 2 Clarified honey av.oz. 17^2 Dissolve the extract by the aid of a gentle heat in the honey, and add the glycerin. — D. Honey of Rose with Borax. Borax gr. 150 Glycerin Gr. 75 Honey of rose oz. 3 Mix and dissolve borax by aid of a gentle heat. — N. F. Honey of Borax. Made by dissolving 150 grains borax in a mixture of 75 grains glycerin and 3 av. ozs. of clarified honey. — N. F. Hydrastin. Extract golden seal, No. 60 powder, by the usual method of percolation, with a mixture of 2 volumes of alcohol with 1 of water, remove the alcohol from the percolate by distillation, evaporate the residue to dryness, and reduce to fine powder. — Brit. Form. Keep in a well-closed vessel. Hydromel. Honey fl.oz. 1 Water fl.oz. 9 Hypodermic Injections. See Injections, Hypodermic. Ichthyol, Deodorization and Dis- guising Taste of. For external use, ichthyol, 50, and 1 each of oil of citronella and euca- lyptus ; or ichthyol, 9, and oil of tur- pentine, 1. For internal use, ichthyol, 5 to 8, pep- permint water, 80, and simple syrup, 20; or, ichthyol, 30 to 60, oil of peppermint, 1, absolute alcohol, 10, and distilled wa- ter, 1000. Infusions. (Infusa.) According to the U. S. P., any ordi- nary infusion, the strength of which is not directed by the physician nor speci- fied by the pharmacopeia, shall be pre- pared by the following formula : The drug, coarse powder. . . .gr. 365 Water, boiling fl.oz. 16 Water, to make fl.oz. 16 Put the drug into a suitable vessel provided with a cover, pour upon it the boiling water, cover the vessel lightly, and let it stand for y 2 hour in a warm place. Then strain (through muslin or flannel), and pass enough water through the strainer to make the colature meas- ure 16 fluidounces. It is advisable to express the sub- stance on the strainer before adding more water. The product represents 5 per cent, of drug. Caution. — The strength of infusions of powerful or energetic substances should be specially prescribed by the physician. Infusions should be made in porce- lain, porcelain-lined or glass vessels. According to the German Pharmaco- poeia, infusions are to be made by pour- ing boiling water on the drug, then heat- ing on a water bath for 5 minutes, stir- ring frequently, allowing to cool, and straining. When the strength of the infusion is not snecified, it is to be made to represent 10 per cent, of drug. Infusion of Broom. (Infusion of Scoparius.) Broom tops, bruised gr. 730 Distilled water, boiling. .. .fl.oz. 16 Infuse in a covered vessel for 15 min- utes, and strain. — Brit. Pharm. This has been introduced in place of the decoction of broom of the Brit. Pharm. of 1885 which was made from 365 gr. of broom tops and 16 fluid- ounces of water. Infusion of Buchu. (Infusum Bar- osmee or Diosmse.) I. Buchu gr. 480 Distilled water, boiling. .. .fl.oz. 16 Mix, let stand in a covered vessel for 2 hours, then strain. — U. S. P. 1870. II. Buchu . gr. 365 Distilled water, boiling. .. .fl.oz. 16 Infuse in a covered vessel for 15 min- utes, and strain. — Brit. Pharm. III. The Eclectic formula is the same as No. II. PHARMACEUTICAL PREPARATIONS. 205 Infusion of Cascarilla. Cascarilla, No. 10 powder... gr. 365 Distilled water, boiling. .. .fl.oz. 16 Infuse in a covered vessel for 15 min- utes, and strain. — Brit. Pharm. Infusion of Catechu. (Compound In- fusion of Catechu, U. S. P. 1870.) Catechu, fine powder gr. 240 Cinnamon, moderately fine powder gr. 60 Water, boiling fl.oz. 16 Macerate in a covered vessel for an hour, and strain. — U. S. P. 1870. Infusion of Chamomile. Roman chamomile gr. 365 Water, boiling fl.oz. 16 Infuse in a closed vessel for y 2 hour, then strain. — Brit. Pharm. 1885. Infusion of Chiretta. Chiretta, cut small gr. 365 Distilled water, boiling. .. .fl.oz. 16 Infuse in a covered vessel for 15 min- utes, and strain. — Brit. Pharm. The Brit. Pharm. also recognizes a "concentrated solution of chiretta" which is 10 times the strength of the above. It is prepared by extracting 8*4 av.ounces of drug in No. 40 powder with a mixture of 4 volumes of alcohol and 15 of water to make 16 fluidounces of product. The infusion may be pre- pared by mixing this with 9 times its volume of water. Infusion of Cinchona. (Acid Infu- sion of Cinchona.) Yellow cinchona, No. 40 powder av.oz. 1 Aromatic sulfuric acid m. 80 Water, to make fl.oz. 16 Mix the acid with 8 fluidounces of water, and moisten the drug with 4 fluidrams of this mixture, pack it firmly in a conical glass percolator, and gradu- ally pour upon, first, the remainder of the mixture, and afterwards water, un- til the infusion measures 16 fluidounces. N. F. and U. S. P. 1890. The acid infusion of cinchona of the Brit. Pharm. is prepared by mixing 365 grains of red cinchona, in No. 40 pow- der, with 16 fluidounces of boiling dis- tilled water, adding 90 m. of aromatic sulfuric acid (corresponding to 65 m. of U. S. P. aromatic sulfuric acid), in- fusing in a covered vessel for one hour, and straining. Infusion of Cloves. Cloves, bruised gr. 180 Distilled water, boiling. .. .fl.oz. 16 « Infuse in a covered vessel for 15 min- utes, and strain. — Brit. Pharm. Infusion of Columbo. (Infusion of Calumba.) I. Columbo, cut small av.oz. y 2 Distilled water, cold.. fl.oz. 16 Macerate for two hours and strain, or extract by percolation with water. — U. S. P. 1870. II. Columbo, thinly sliced gr. 365 Distilled water, cold fl.oz. 16 Infuse for half an hour, and strain. — Brit. Pharm. The Brit. Pharm. also recognizes a "concentrated solution of columbo" which is 10 times the strength of the above. It is prepared by macerating 8*4 av.ounces of drug in No. 5 powder with 8 fluidounces of distilled water for 24 hours, expressing strongly, again mac- erating the drug with 8 fluidounces of distilled water for 24 hours, and again expressing strongly. Mix the expressed liquids, heat for 5 minutes to 80 deg. C, allow to cool, add the alcohol, set aside for some time, then decant the clear liquid or filter, adding to the clear liquid enough distilled water to make 16 fluidounces. The infusion may be prepared from this by mixing 1 volume with 9 volumes of water. Infusion of Cusparia. Cusparia bark, No. 20 powd..gr. 365 Distilled water, boiling. .. .fl.oz. 16 Infuse in a covered vessel for 15 min- utes, and strain. — Brit. Pharm. The Brit. Pharm. also recognizes a "concentrated solution of cusparia" 206 STANDARD FORMULARY OF which is 10 times the strength of the above and is prepared by extracting 8)4 av. ounces of drug in No. 40 powder with a mixture of 4 volumes of alcohol and 15 of water to make 16 fluidounces. The infusion may be prepared from this by adding to 1 volume of this 9 volumes of water. Infusion of Digitalis. Digitalis, bruised- av.oz. % Alcohol fl.dr. 13 Cinnamon water fl.dr. 19 Water, boiling; fl.oz. 8 Water, cold, to make fl.oz. 16 Upon the digitalis pour the boilinqr water, and allow it to macerate for one hour. Then strain, add the alcohol and cinnamon water to the colature, and pass enough cold water through the residue on the strainer to make the liquid measure 16 fluidounces. — U. S. P. Infusion of digitalis of the Brit. Pharm. is prepared from 50 grains of digitalis, in No. 20 powder, and 16 fluid- ounces of boiling distilled water, in- fusing in a covered vessel for 15 min- utes, and straining. The Brit. Pharm. recognizes a "con- centrated infusion of digitalis" made as follows : Digitalis, No. 20 powder gr. 400 Alcohol, 90 per cent fl.oz. 4 Distilled water, to make. . .fl.oz. 16 Macerate the drug with 12 fluidounces of water for 24 hours, strain, and to 8 fluidounces of the colature add the al- cohol. Again macerate the leaves with a second 12 fluidounces of the water for 6 hours, and strain ; macerate with a third 12 fluidounces of water for 6 hours, and strain. Mix the residue of the first with the second and third liq- uids, evaporate at a low temperature to 4 fluidounces, add this to the portion set aside. This preparation is 8 times the strength of the Brit. Pharm. infusion. Infusion of Ergot. Ergot, freshly crushed gr. 365 Distilled water, boiling. .. .fl.oz. 16 Infuse in a covered vessel for 15 min- utes, and strain. — Brit. Pharm. Infusion of Gentian, Compound. Gentian gr. 240 Bitter orange peel gr. 60 Coriander gr. 60 Alcohol fl.oz. 2 Water sufficient Extract the drugs in the form of moderately coarse powder, by percola- tion, using as a menstruum a mixture of the alcohol with 14 fluidounces of water, to be followed by water, until 16 fluidounces of percolate are obtained. — U. S. P. 1870. The Brit. Pharm. directs 90 grains each of gentian root, thinly sliced, and dried bitter orange peel, cut small, and 180 gr. of fresh lemon peel, cut small, to be infused with 16 fluidounces of boiling distilled water in a covered ves- sel for 15 minutes, and strain. See also Infusion of Gentian, Com- pound, Stronger. Infusion of Gentian, Comp. Stronger. Gentian gr. 960 Coriander gr. 240 Bitter orange peel gr. 240 Diluted alcohol, to make.. fl.oz. 16 Reduce the drugs to a moderately coarse (No. 40) powder, moisten it with diluted alcohol, pack it in a percolator, and percolate with diluted alcohol, until 16 fluidounces of percolate are obtained. When compound infusion of gentian is prescribed, it may be prepared by mixing 1 volume of this preparation with 3 of water. II. The Brit. Form, recognizes a sim- ilar preparation under the name "con- centrated compound infusion of gen- tian," as follows : Gentian, No. 20 powder gr. 800 Bitter orange peel, dried gr. 800 Lemon peel, dried gr. 400 Tinct. of fresh lemon peel.. fl.dr. 6 l / 2 Alcohol, 90 per cent fl.oz. 3*4 Distilled water, to make... fl.oz. 16 Mix the gentian and orange and lem- on peels, pour over them 16 fluidounces of water, macerate 24 hours, and ex- press. Reserve 8 fluidounces and to it add the tincture and alcohol. Treat the marc with two further macerations of 16 fluidounces of distilled water for 6 PHARMACEUTICAL PREPARATIONS. 207 hours, express as before, mix the two liquids, adding any left over from the first maceration. Evaporate this liquid to 4 fluidounces, and add it to the re- served liquid to make 16 fluidounces. This preparation is 8 times the strength of the Brit. Pharm. compound infusion of gentian. The tincture of fresh lemon peel for this preparation is to be made by mac- erating 2 av. ounces of the grated outside peel of fresh lemons with 4 fluidounces of alcohol, and filtering. Infusion of Geranium, Comp. (Com- pound Infusion of Cranesbill.) Geranium av.oz. J4 Witchhazel av.oz. *4 Black cohosh av.oz. *4 Golden seal av.oz. Y\ Water, boiling fl.oz. 16 Bruise the drugs to coarse powder, pour on the water, and digest at a gentle heat, in a closed vessel, for 2 hours, then strain. If required, 30 grains of powdered alum may be added. — Eclectic. This is used as an astringent wash in aphthous sore mouth and throat. Infusion, of Golden Seal, Compound. Golden seal av.oz. y 2 Blue cohosh av.oz. y 2 Witchhazel bark av.oz. y 2 Alum gr. 60 Water, boiling fl.oz. 16 Honey sufficient Digest trie drugs in a closed vessel with the boiling water, at a gentle heat, for half an hour, strain, add the alum, dissolve, and then add sufficient honey to sweeten thoroughly. — Eclectic. Used as wash for various forms of sore mouth, and as a gargle. Infusion of Hops. (Infusum Lupuli.) Hops, freshly broken gr. 365 Distilled water, boiling. .. .fl.oz. 16 Infuse in a covered vessel for 15 min- utes, and strain. — Brit. Pharm. Infusion of Kousso. (Infusion of Brayera or Hagenia or Cusso.) Kousso, No. 20 powder. . . .av.oz. 1 Boiling water fl.oz. 16 Pour the boiling water upon the drug, and let it macerate in a covered vessel until cool. This infusion should be dispensed without straining. — N. F. and U. S. P. 1880. Infusion of Linseed. (Infusion of Flaxseed — Compound Infusion of Linseed, U. S. P. 1870.) Linseed, whole gr. 240 Licorice root, bruised gr. 120 Water, boiling fl.oz. 16 Macerate for 2 hours, then strain. — U. S. P. 1870. Infusion of Orange Peel. Bitter orange peel, dried, cut small gr. 365 Distilled water, boiling fl.oz. 16 Infuse in a covered vessel for 15 min- utes, and strain. — Brit. Pharm. Infusion of Orange Peel, Compound. Bitter orange peel, dried, cut small gr. 180 Lemon peel, fresh, cut small.gr. 90 Clove, bruised gr. 45 Distilled water, boiling. .. .fl.oz. 16 Infuse in a covered vessel for 15 min- utes, and strain. — Brit. Pharm. Infusion of Parsley, Compound. (In- fusum Apii Compositum.) Parsley root, coarsely bruised av.oz. 1 Parsley seed av.oz. 1 Iron subcarbonate av.oz. 1 Horseradish root, small pieces av.oz. l / 2 Juniper berries, finely bruised av.oz. y Squill, finely brused av.oz. *4 White mustard seed, finely bruised av.oz. *4 Mandrake root, finely bruised av.oz. V\ Queen-of-the-meadow, finely bruised av.oz. y Cider fl.oz. 48 Boil the cider, pour on the drugs con- tained in an earthen vessel, and digest at a gentle heat for 24 hours. — Eclectic. The cider should not be too hard nor too new, but preferably pleasantly tart. The above is used in some varieties of dropsy. 208 STANDARD FORMULARY OF Infusion of Quassia. Quassia, finely rasped gr. 73 Distilled water, cold fl.oz. 16 Infuse in a covered vessel for 15 min- utes, and strain.— Brit. Pharm. The Brit. Pharm. also recognizes a "concentrated solution of quassia" which is 10 times the strength of the above and is prepared by extracting 730 grains of drug in No. 40 powder with a mix- ture of 4 volumes of alcohol and 15 of water to make 16 fluidounces. The in- fusion may be prepared by mixing 1 volume of this with 9 volumes of water. Infusion of Rhatany. (Infusion of Krameria.) Krameria. bruised gr. 365 Distilled water, boiling fl.oz. 16 Infuse in a covered vessel for 15 min- utes, and strain. — Brit. Pharm. The Brit. Pharm. also recognizes a "concentrated solution of rhatany" which is 10 times the strength of the above and is prepared by extracting S X A av. ounces of drug in No. 40 powder with a mixture of 4 volumes of alcohol and 15 of water to make 16 fluidounces. The infusion may be prepared by mix- ing 1 volume of the above with 10 vol- umes of water. Infusion of Rhubarb. Rhubarb, thin slices gr. 365 Distilled water, boiling. .. .fl.oz. 16 Infuse in a covered vessel for 15 min- utes, and strain. — Brit. Pharm. The Brit. Pharm. also recognizes a ''concentrated solution of rhubarb" which is 10 times the strength of the above and is prepared by extracting 8^4 av. ounces of drug in No. 40 powder with a mixture of 4 volumes of alcohol and 15 of water to make 16 fluidounces. The infusion may be prepared by mix- ing 1 volume of this with 9 volumes of water. Infusion of Rose, Compound. (Acid Infusion of Roses.) Red rose petals gr. 95 Diluted sulfuric acid m. 70 Sugar gr. ,300 Boiling water fl.oz. 16 30 16 Pour the boiling water upon the rose in a glass or porcelain vessel, add the acid, cover the vessel, and macerate for an hour. Then dissolve the sugar in the liquid and strain.— N. F. and U. S. P. 1870. The acid infusion of roses of the Brit. Pharm. is made from 180 grains of dried red rose petals, adding to these a mixture of 90 m. of diluted sulfuric acid (equal to 65 m. of U. S. P. diluted sulfuric acid) and 16 fluidounces of boil- ing distilled water, infusing in covered vessel for 15 minutes, and straining. Infusion of Sage. Sage gr. 240 Water, boiling fl.oz. 16 Mix, let stand in a covered vessel for half an hour, and strain. — U. S. P. 1870. Infusion of Sage, Compound. Sage av.oz. y 2 Hyssop av.oz. y 2 Borax gr. Water, boiling fl.oz. Digest the drugs, in a closed vessel, with the water, for half an hour, strain, and dissolve the borax in the colature. Used as a mouth wash and gargle. — Eclectic. Infusion of Senega. Senega root, No. 10 powder.gr. 365 Distilled water, boiling. .. .fl.oz. 16 Infuse in a covered vessel for half an hour and strain. — Brit. Pharm. The Brit. Pharm. also recognizes a '"'concentrated solution of senega" which is 10 times the strength of the above and is prepared by extracting 8^+ av.- ounces of the drug in No. 20 powder with a mixture of 8 volumes of alcohol and 19 of water to make 16 fluidounces. The infusion may be prepared by mix- ing 1 volume of this with 9 volumes of water. Infusion of Senna. I. Senna gr. 480 Coriander, bruised gr. 60 Distilled water, boiling. .. .fl.oz. 16 Infuse for an hour, and strain. — U. S. P. 1870. PHARMACEUTICAL PREPARATIONS. 209 II. Senna gr. 730 Ginger, sliced gr. 45 Distilled water, boiling. .. .fl.oz. 16 Infuse in a covered vessel for 15 min- utes, and strain. — Brit. Pharm. The Brit. Pharm. also recognizes a "concentrated solution of senna" which is 10 times the strength of the above and is prepared as follows : Senna, No. 5 powder av.oz. 16^ Tincture of ginger, U. S. P. fl.oz. 1 Alcohol fl.dr. 21 Distilled water sufficient Divide the senna into three equal por- tions, slightly moisten one portion with distilled water, pack in a percolator, set aside for 24 hours, then pass distilled water through it until 4 fluidounces of percolate are obtained. Slightly moist- en the second portion of drug with this percolate, set aside for 24 hours, and then pass the remainder of the perco- late, adding to the drug an additional 4 fluidounces of distilled water. Treat the remaining portion of drug in the same manner, and continue successive percolation with water through the three portions of drug until a quantity of I2}i fluidounces of percolate has been obtained from the third percolator. Heat the liquid to 80 deg. C. for 5 minutes, cool, add the tincture and alcohol, pre- viously mixed, set aside for 7 days, and filter. The product should measure 16 fluidounces. The infusion may be prepared by mix- ing 1 volume of this with 9 volumes of water. Infusion of Senna, Compound. (Black Draught — Vienna Draught — Wiener Trank.) I. Senna, cut av.oz. 1 Manna av.oz. 2 Magnesium sulfate av.oz. 2 Fennel, bruised gr. 145 Water, boiling fl.oz. 12^ Water, cold, to make fl.oz. 16 Upon the senna and fennel pour the boiling water and macerate for half an hour. Then strain with expression, dis- solve the salt and manna in the cola- ture, again strain, and add enough wa- ter to the strainer containing the senna and fennel to make the liquid measure 16 fluidounces. — U. S. P. II. Senna (India), cut av.oz. 2 Rochelle salt av.oz. 2 Sodium carbonate gr. 17 Manna av.oz. 4 Alcohol fl.oz. 1 Water sufficient Upon the senna pour 18 fluidounces of boiling water, heat the whole on a water bath for 5 minutes, allow to cool, strain with expression, in the colature dissolve the rochelle salt, sodium carbonate, and manna. Strain the liquid, add boiling water to the colature to make it weigh 19 av.ounces, add the alcohol, let the mixture stand for 24 hours, and decant the clear liquid (measuring about 16 fluidounces). — Germ. Pharm. III. The "black draught" of the Brit. Pharm. is quite different from either of the preceding and is called compound mixture of senna. It is prepared as follows : Magnesium sulfate av.oz. 4^4 Fluid extract of licorice. .. .fl.dr. 6y 2 Compound tincture of carda- mom fl.dr. 13 Aromatic spirit of ammo- nia ..fl.dr. 6y 2 Infusion of senna, Brit. Pharm., to make fl.oz. 16 Dissolve the magnesium sulfate in 8 fluidounces of the infusion, add the mixed fluid extract, tincture and spirit, and then add the remainder of the in- fusion. Infusion of Serpentaria. (Infusion of Virginia Snakeroot.) Serpentaria, No. 10 powder, .gr. 365 Distilled water, boiling. .. .fl.oz. 16 Infuse in a covered vessel for 15 min- utes, and strain. — Brit. Pharm. The Brit. Pharm. recognizes a "con- centrated solution of serpentaria" which is 10 times the strength of the above and is prepared by extracting 8J-4 av.- ounces of drug in No. 40 powder with a mixture of 4 volumes of alcohol and 15 of water to make 16 fluidounces. The 210 STANDARD FORMULARY OF infusion may be prepared by mixing one volume of this with 9 volumes of water. Infusion of Tar. (Tar Water— Aqua Picis.) Pine tar fl.oz. 4 Water fl.oz. 16 Mix, shake frequently during 24 hours, decant the supernatant liquid, and filter.— U. S. P. 1870. II. Formula for tar water : Pine tar part by weight 1 Pumice, coarse powder parts 3 Distilled water sufficient Mix the tar and pumice, the latter having previously been washed with wa- ter and dried. To prepare the water, mix 4 av.ounces of this mixture with gY 2 fluidounces of distilled water, agi- tate for 5 minutes, and filter.— Germ. Pharm. This preparation should be freshly prepared when wanted for use or at least should not have been long on hand when it is dispensed. Infusion of Trailing Arbutus, Com- pound. (Infusion of Epigaeae Compositum — Diuretic Comp'd.) Trailing arbutus av.oz. *4 Queen-of-the-meadow root.. av.oz *4 Dwarf elder bark av.oz. ]4- Marshmallow root av.oz. Y\ Water, boiling fl.oz. 8 Holland gin fl.oz. 8 Honey sufficient Bruise the drugs to very coarse pow- der, pour on the water and gin, and digest at a gentle heat for 6 hours ; then strain, and add enough honey to render the liquid pleasantly sweet. — Eclectic. This is used in gravel and various disorders of the urinary organs. Infusion of Uva Ursi. (Infusion of Bearberry.) Uva ursi, bruised gr. 365 Distilled water, boiling. .. .fl.oz. 16 Infuse in a covered vessel for 15 min- utes, and strain. — Brit. Pharm. Infusion of Valerian, Compound. Valerian, cut av.oz. 1 Acetic ether m. 40 Syrup of cinnamon fl.oz. i l / 2 Water, hot sufficient Make 7V2 fluidounces of infusion from the valerian and water, and, when cold, add the other ingredients. — H. Infusion of Wild Cherry. Wild cherry, No. 20 powder.gr. 290 Glycerin fl.dr. 6 l / 2 Water, to make fl.oz. 16 Moisten the powder with 1 fluidounce of water, macerate for 1 hour, pack firmly into a conical glass percolator, and, having placed the glycerin in the receiving vessel, gradually pour water on the drug until the percolate meas- ures 16 fluidounces. — N. F. Inhalations. (Vapors.) Preparations by this name were rec- ognized in the Brit. Pharm. of 1885, but not in the 1898 edition. These are hard- ly pharmaceutical in character and are usually to be prepared in the bedcham- ber, but this reference to them can hard- ly be considered out of place. The sub- stance or mixture of substances is to be placed with water, cold or boiling, in a suitable apparatus, and the vapor arising is to be inhaled. Inhalation of Chlorin. (Vapor of Chlorin.) Chlorinated lime ("chlorid of lime") av.oz. 2 Water, cold sufficient Put the powder into a suitable ap- paratus, moisten it with water, and let the vapor that arises be -inhaled. — Brit. Pharm. 1885. Inhalation of Conine. (Vapor of Conine.) Juice of hemlock, fl.dr. 4 Solution of potassa m. 80 Distilled water fl.oz. 1 Put 20 minims of this mixture on a sponge, in a suitable apparatus, so that the vapor of hot water passing over it may be inhaled. — Brit. Pharm. 1885. The potassa liberates the volatile al- kaloid conine from the hemlock juice. Inhalation of Creosote. Creosote, beechwood m. 15 Water, boiling fl.oz. 10 Mix in an apparatus so arranged that air may be made to pass through the solution and may afterward be inhaled. —Brit. Pharm. 1885. PHARMACEUTICAL PREPARATIONS. 211 Inhalation of Fir-Wool Oil. (In- halation of Oil of Wild Pine, Scotch Fir, or Pinus Sylvestris.) Fir- wool oil m. 40 Magnesium carbonate, light, .gr. 20 Water, to make fl.oz. 1 Triturate the oil with the magnesium carbonate and add the oil. One fluidram of this is to be mixed with id fluidounces each of cold and boiling water in an apparatus so ar- ranged that air may be made to pass through the solution and may after- wards be inhaled. — Brit. Pharm. 1885. Inhalation of Hydrocyanic Acid. Diluted hydrocyanic acid.m. 10 to 15 Water, cold fl.dr. 1 Mix in a suitable apparatus and let the vapor that arises be inhaled. — Brit. Pharm. 1885. Inhalation of Iodin. Tinct. of iodin, Brit. Pharm.. fl.dr. I Water, boiling fl.oz. 1 Mix in a suitable apparatus which can be gently heated ; let the vapor that arises be inhaled. — Brit. Pharm. 1885. Inhalation, Iodin, Ethereal. This has been advised: Iodin gr. 3 Ether fl.dr. 2 Carbolic acid fl.dr. 2 Creosote or thymol gr. 60 Alcohol fl.dr. 3 Ten minims of this are to be dropped on the respirator for dry inhalation. This is similar to carbolized solution of iodin. Inhalation, Warren's. Thymol gr. 8 Sodium borate gr. 300 Glycerin fl.oz. ij4 Camphor water fl.oz. 2^ Tar water fl.oz. 7 To be used as an inhalation by means of an atomizer. Injections, Hypodermic. Preparations of this name are recog- nized by the Brit. Pharm. They are aqueous solutions of active substances, usually alkaloidal salts, intended for subcutaneous use. Distilled water only must be used, it is to be boiled and Ik cooled before use, the solution should be perfectly clear, and it should be made only as wanted for use. The Brit. Pharm. 1885 used camphor water as the solvent, instead of distilled water, in some instances. Injection, Hypodermic, of Apomor- phine. Apomorphine hydrochlorid. .gr. 1 Diluted hydrochloric acid. .. .m. 1 Distilled water m. no Boil the water for a few minutes, cool, add the acid, dissolve the alkaloidal salt in this liquid, and add, if necessary, enough recently boiled and cooled dis- tilled water to make no m. of liquid.— Brit. Pharm. In the Brit. Pharm. 1885 this was pre- pared from 2 gr. of the salt and 100 m. of camphor water. Injection, Hypodermic, of Cocaine. Cocaine hydrochlorid gr. S3 Salicylic acid gr. l /> Distilled water fl.dr. 6 Boil the water, add the acid, dissolve the cocaine salt in the solution when cool, and add, if necessary, enough re- cently boiled and cooled distilled water to make 6 fluidrams of solution. no minims contain about 10 gr. of cocaine hydrochlorid. — Brit. Pharm. Injection, Hypodermic, of Curare. Curare gr. 5 Distilled water sufficient Reduce the curare to powder in such a way as to prevent it from coming in contact with the naked hand or any other portion of the body, add distilled water to form a thin paste, transfer to a small funnel plugged with absorbent cotton, and gradually pour upon it dis- tilled water until 1 fluidram is obtained. If the injection is required in haste, proceed in this manner: To the 5 gr. of curare, reduced to powder, add 1 fluidram of distilled wa- ter, pour on a filter, and when the liquid ceases to drop, pour on the contents of the filter enough distilled water to make 1 fluidram of filtrate.— Brit. Form. 212 STANDARD FORMULARY OF Injection, Hypodermic, of Ergot or Ergotin. Extract of ergot gr. ioo Phenol (pure carbolic acid).gr. 3 Distilled water m. 220 Mix the phenol with the water, boil for a few minutes, cool, add the extract, dissolve, and then add enough recently boiled and cooled distilled water to make 330 minims of solution. — Brit. Pharm. Injection of Lead and Opium. Lead acetate gr. 8 Zinc sulfate gr. 8 Tincture of opium fl.dr. 2 Water, to make fl.oz. 4 — New York Hospitals. Injection, Hypodermic, of Morphine. Morphine tartrate gr. 5 Distilled water sufficient Dissolve the morphine salt in enough recently boiled and cooled distilled wa- ter to make no minims of solution. — Brit. Pharm. The preparation of the Brit. Pharm. 1885 contained n gr. of morphine ace- tate to no m. of injection. Injection, Urethral. Boric acid gr. 60 Zinc sulfate gr. 8 Alcohol fl.dr. 2 Water, to make fl.oz. 4 — New York Hospitals. Injection, Urethral, Lloyd's. Zinc acetate gr. 6 Lead, acetate gr. 6 Glycerite of hydrastis fl.oz. i]/ 2 Water, to make fl.oz. 4 — New York Hospitals. Iodoform, Aromatic or Deodorized. Iodoform gr. 96 Cumarin gr. 4 Mix them intimately by trituration. Should cumarin not be available, or should it be objectionable to the patient, the odor of iodoform may also be more or less masked by many essential oils, for instance those of peppermint, cloves, cinnamon, citronella, bergamot, sassa- fras, eucalyptus, etc. Another efficient covering agent is freshly-roasted and powdered coffee. • The odor of iodoform may be re- moved from the hands or anv utensils which it has come in contact with, by washing them with an aqueous solution of tannic acid or by rubbing with oil of turpentine. — N. F. Iridin. Extract blue flag, No. 60 powder, with a mixture of 2 volumes of alcohol and 1 of water by the usual method of per- colation, remove the alcohol from the percolate by distillation, evaporate the residue to dryness, and reduce to fine powder. — Brit. Form. Keep in a well-closed vessel. Iron Ammonio-Chlorid. (Amoniated Iron.) Ammonium chlorid, moder- ately coarse powder av.oz. 5 Solution of ferric chlorid. . .fl.dr. 6 Mix the ammonium chlorid with the solution in a porcelain capsule, and heat on a water bath, stirring constantly, un- til dry. — Germ. Pharm. modified. Keep protected from light. Iron Ammonium Citrate. See Iron (Ferric) Citrate. Iron and Ammonium Tartrate. (Am- monio-Ferric Tartrate — Am- monio — Tartrate of Iron.) Solution of iron (ferric) sul- fate fl.oz. 4 Tartaric acid gr. 530 Distilled water fl.oz. 8 Ammonia water, 10 p. c, water, each sufficient To 4H fluidounces of ammonia water, previously diluted with 10 fluidounces of cold water, add slowly with constant stirring, the iron solution previously diluted with 52 fluidounces of cold wa- ter. When the precipitate has subsided. draw off the clear, supernatant liquid by means of a siphon, then mix the pre- cipitate intimately with 30 fluidounces of cold water, again draw off the clear liquid, and repeat the washing with wa- ter in the same manner until the de- canted liquid gives no more than a slight cloudiness with barium chlorid so- lution. Then transfer the precipitate to a wet muslin strainer, allow it to drain, and express the water as completely as possible. Dissolve one-half the tartaric PHARMACEUTICAL PREPARATIONS. 213 acid in the distilled water, neutralize the solution exactly with ammonia water, then add the other half of the acid, and dissolve it by the application of a gen- tle heat. Now add the moist ferric hy- drate, in successive portions, stirring constantly, and continue the heat, which should not exceed 60 deg. C. until the hydrate is dissolved. Filter the solution while hot, evaporate it in a porcelain vessel, at or below the above-mentioned temperature, to the consistence of syrup, and spread it on plates of glass, so that when dry the salt may be obtained in scales.— U. S. P. 1890. Keep the product in Well-stoppered bottles, protected from light. Iron (Ferrous) Carbonate, Sacchar- ated. Ferrous sulfate, pure av.oz. 2 Sodium bicarbonate, pure.. av.oz. 1. .gr. 175 Sugar, fine powder, distilled water, each sufficient Dissolve the ferrous salt in 8 fluid- ounces of distilled water and the sodium bicarbonate in 20 fluidounces of distilled water, at a temperature not above 50 deg. C, and filter the solutions sepa- rately. To the sodium salt, contained in a flask or bottle having the capacity of about 40 fluidounces (it might even be larger), add gradually the ferrous solution, and mix thoroughly during the addition by vigorously rotating the flask or bottle. Fill up the flask or bottle with boiling distilled water, cork it loosely, and set the mixture aside. When the precipitate has subsided, draw off the clear, supernatant liquid by means of a siphon and then fill the flask again with hot distilled water and shake it. Again draw off the clear liauid and re- peat the washing with hot distilled wa- ter in the same manner until the de- canted liquid gives merely a slight cloudiness with barium chlorid test solution. Finally drain the precipitate thoroughly on a muslin strainer, trans- fer it to a porcelain capsule containing 3/4 av.ounces of sugar, and mix inti- mately. Evaporate the mixture to dry- ness on a water bath, reduce it to pow- der and mix intimately with it, if nec- essary, enough well-dried sugar to make the product weigh 4 av.ounces. Keep the product in small, well-stop- pered bottles. The product should contain at least 15 per cent, of ferrous carbonate. — U. S. P. The Brit. Pharm. precipitates the iron carbonate with ammonium carbonate in- stead of sodium bicarbonate. Iron (Ferric) Citrate. The U. S. P. recognizes two scale preparations of this kind, one being called "iron citrate" (or "ferric cit- rate"), the other "iron and ammonium citrate." The latter is also called "ara- monio-ferric citrate," but is known com- mercially more frequently as "soluble citrate of iron," it being more quickly soluble than the former compound. I. The first one is prepared by evap- orating any conveinent quantity of so- lution of iron citrate (which see) on a water bath, at a temperature not ex- ceeding 60 deg. C, to the consistence of syrup, and spreading on plates of glass so that when dry the salt may be ob- tained in scales. After spreading on plates of glass (porcelain is equally good), it should be kept at a temperature of about 35 deg. C. to facilitate the drying. The product, which is in garnet-red scales, should be preserved in well-stop- pered bottles protected from light. II. Iron and ammonium citrate ("soluble citrate of iron") : Solution of iron citrate fl.oz. 5 Ammonia water (10 p. c.) . . fl.oz. 2 Mix the solution with the water, evap- orate the mixture by means of a water bath at a temperature not exceeding 60 deg. C. to the consistence of syrup and spread it on plates of glass so that when dry the salt may be obtained in scales. The drying on the plates should be facilitated as in the preceding case. 214 STANDARD FORMULARY OF The product, which is in garnet-red scales, should be preserved in well-stop- pered bottles protected from light. For making this preparation, some formulas recommend the addition to the solution of iron citrate, not of ammonia water, but a solution of ammonium cit- rate. This is the method of the Nor- wegian Pharmacopeia. Iron (Ferric) Hydrate. (Magma, Fer- ri Hydroidi.) Solution of iron (ferric) sul- fate fl.oz. 4 Ammonia water fl.oz. $ l / 2 Water sufficient To the ammonia water, previously di- luted with 20 fluidounces of cold water, add gradually under constant and vigor- ous stirring the iron solution previously diluted with 40 fluidounces of cold wa- ter. As soon as the precipitate has sub- sided, draw off the clear liquid by means of a siphon, then mix the precipitate intimately with about 40 fluidounces of cold water, again draw off the clear liquid after subsidence of the precipi- tate, and repeat this operation until a portion of the decanted liquid gives not more than a slight cloudiness with bari- um chlorid test solution. Finally trans- fer the precipitate to a wet muslin strainer, and after it has drained mix it with sufficient cold water to make the mixture weigh 12 av. ounces. — N. F. The ammonia water must be 10 p. c. in strength; if weaker, proportionately more of it must be used and less water, or if stronger, less may be used, and more water. Iron (Ferric) Hydrate with Mag- nesia. (Arsenic Antidote.) Solution of iron (ferric) sul- fate fl.dr. 5 Light magnesium oxid gr. 75 Water sufficient Mix the solution with 2 fluidounces of distilled water and keep the liquid in a large, well-stoppered bottle. Rub the magnesia with cold water to a smooth and thin mixture, transfer this to a bottle capable of holding 16 fluid- ounces, and fill with water to about three-fourths of its capacity. When the preparation is wanted for use, shake the magnesia mixture to a homogeneous, thin magma, gradually add it to the iron solution, and shake them together until a uniform, smooth mixture results. -U. S. P. It is supposed that the two mixtures be kept on hand so as to be readv for immediate use in case of acute arsen- ical poisoning. Iron (Ferric) Hypophosphite. Iron and ammonium sulfate (U. S. P.), perfect crys- tals av.oz. 3 Sodium hypophosphite av.oz. 2 Distilled water sufficient Dissolve the iron and ammonium sul- fate in 11 fluidounces. and the sodium hypophosphite in 3*^ fluidounces of dis- tilled water, and, if necessary, filter each solution. Then mix them, and stir thoroughly; after a short time transfer the mixture to a close linen or muslin strainer, and wash the precipitate with distilled water, until the washings run off tasteless. Transfer the strainer to a warm place and, when the contents are dry, preserve them for use. Hypophosphite of iron (ferric) may also be prepared in the following man- ner : Calcium hypophosphite av.oz. 2 Solution of chlorid of iron (U. S. P.), distilled water, each sufficient Dissolve the calcium hypophosphite in 24 fluidounces of distilled water, and fil- ter the solution. To this add solution of chlorid of iron, in small portions, stirring well each time and allowing the precipitate to subside before adding a fresh portion. Toward the end, remove a small quantity of the clear supernatant liquid, add to it some solution of chlorid of iron diluted with 10 times its volume of water, and observe whether any tur- bidity occurs either at once or after a few minutes. If it remains clear, the precipitation may be regarded as com- plete. Then transfer the mixture to a close linen or muslin strainer, and wash PHARMACEUTICAL PREPARATIONS. 215 the precipitate with distilled water, un- til the washings run off tasteless. Trans- fer the strainer to a warm place and, when the contents are dry, preserve them for use. Hypophosphite of iron is rendered soluble in water by mixing it with about an equal weight of potassium citrate, or some other alkali citrate. Theoret- ically, ioo parts of iron and ammonium sulfate will yield 51.9 parts, and 100 parts of calcium hypophosphite will yield 85.3 parts of dry hypophosphite of iron (ferric). — N. F. (1st ed.). Iron (Ferrous) Iodid, Saccharated. (Saccharated Ferrous Iodid.) Iron, in the form of fine, bright wire, and cut into small pieces (so-called "card-teeth" are excellent ).gr. 210 Reduced iron gr. 36 Iodin av.oz. 1 . .gr. 155 Distilled water, sugar of milk recently dried, each . sufficient Mix the iron wire, iodin, and iY 2 fiuidounces of distilled water in a flask of thin glass, shake the mixture occa- sionally until the reaction ceases and the solution has acquired a green color and lost the odor of iodin; then filter through a small, well-wetted filter into a porcelain capsule containing 3 av.- ounces of milk sugar. Rinse the flask and iron wire with a small quantity of distilled water, pass the rinsings through the filter into the capsule, and evaporate on a water bath with fre- quent stirring until a dry mass results. Transfer this quickly to a heated iron mortar, reduce to powder, and mix it intimately with the reduced iron and enough milk sugar to make the final product weigh 8 av.ounces. Transfer the product at once to small and perfectly dry, well-stoppered bot- tles, to be kept in a cool, dark place. The product contains 20 p. c. of fer- rous iodid (twice as much as syrup of iron iodid). It is soluble in 7 parts of water.— U. S. P. 1890. Iron Oxid, Soluble or Saccharated. (Eisen Zucker.) Solution of iron chlorid (U. S. P.) ... av.oz. 2 (about fl.dr. ny 2 ) Sodium carbonate, pure, crystal av.oz. 2*4 Caustic soda, pure gr. 30 Water, sugar, each sufficient Mix the iron solution with 13^2 fluid- ounces of water, and to this liquid add gradually, with constant stirring, the sodium carbonate dissolved in 13^2 fluid- ounces of water until no more precipi- tation occurs, being careful towards the end of the process to add but a little of the carbonate at a time, and to allow the precipitate to subside before adding more of the precipitant. Then allow the precipitate to subside, decant the moth- er-liquor, and wash the precipitate by repeated affusion and decantation of dis- tilled water, until the washings when mixed with 5 volumes of distilled water no longer make an opalescent mixture with silver nitrate solution. Transfer the precipitate to a dampened piece of muslin, and express gently so as to re- move most of the contained water. Then mix the precipitate in a porcelain cap- sule with 4 l / 2 av.ounces of sugar and 30 gr. of pure caustic soda, the latter pre- viously dissolved in. 3 fluidrams of wa- ter, heat cautiously until the liquid is clear, and evaporate, with constant stir- ring, to dryness. Mix with enough sugar to make 8^4 av.ounces, mix well, reduce the whole to moderately fine powder. — N. F. Iron (Ferric) Phosphate, Soluble. Iron citrate av.oz. 5 Sodium phosphate, unefflo- resced (i. e., clear crys- tals) av.oz. 5 l / 2 Distilled water fl.oz. 10 Dissolve the iron salt in the distilled water by heating on a water bath. To this solution add the sodium phosphate and stir constantly until it is dissolved. Evaporate the solution on the water bath at a temperature not exceeding 60 deg. C, to the consistence of thick syr- up and spread on plates of glass (or 216 STANDARD FORMULARY OF porcelain) so that it may dry in scales. The drying on the plates may be fa- cilitated by the use of a temperature of about 35 deg. C. The product should be preserved in dark amber-colored, well-stoppered bot- tles.— U. S. P. 1800. This iron phosphate is not to be con- founded with the blue phosphate of iron of the British Pharmacopeia and of the U. S. P. 1870, which is made by pre- cipitation from ferrous sulfate and is bluish powder, nor with the white phos- phate of iron made by precipitation from solution of ferric sulfate which is also a powder. Iron and Potassium Tartrate. (Po- tassio-Ferric Tartrate — Tarta- rated Iron.) Solution of iron (ferric) sul- fate fl.oz. 4 Potassium bitartrate gr. 695 Distilled water fl.oz. 12- Ammonia water, 10 p. c, wa- ter, each sufficient Precipitate the ferric hydrate from the iron solution with ammonia water, wash, drain, and express it as in making the tartrate of iron and ammonia (which see). Then mix the potassium salt with the distilled water in a porce- lain vessel, heat the mixture on a water bath to a temperature not exceeding 60 deg. C. and gradually add the moist ferric hydrate, stirring constantly until it is dissolved. Filter the liquid while hot and let the filtrate stand in a dark, cool place for 24 hours. Then stir it well with a porcelain or glass spatula so that the precipitate which has formed may be thoroughly incorporated with the liquid. Now add very cautiously just enough ammonia water to dissolve the precipitate, evaporate the solution in a porcelain vessel, at or below the above -mentioned temperature, to the consistence of syrup, and spread it on plates of glass (or porcelain) so that when dry the salt may be obtained in scales. The drying on glass or porcelain plates may be facilitated by the use of a temperature of about 35 deg. C. The product should be preserved in well-stoppered bottles, protected from light.— U. S. P. 1890. Iron (Ferric) Pyrophosphate, Solu- ble. Prepare like iron phosphate, soluble (which see), but using, instead of the sodium phosphate, 5 av. ounces of so- dium pyrophosphate, also uneffloresced. — U. S. P. 1890. In the U. S. P. 1870, this compound was made by first preparing precipitated ferric pyrophosphate, then dissolving this in a solution of ammonium citrate, and then evaporating and scaling as be- fore. This soluble iron phosphate is not to be confused with the white iron pyro- phosphate, in powder, made by precipi- tation, which is also commercially avail- able. Iron and Quinine Citrate. Iron citrate av.oz. 7 Quinine (alkaloid), dried at 100 deg. C. to constant weight av.oz. 1 Citric acid av.oz. ^ Distilled water sufficient Dissolve the iron citrate in 13 fluid- ounces of distilled water by heating on a water bath to a temperature not ex- ceeding 60 deg. C. To this solution add the quinine and citric acid previously triturated with 2 fluidounces of distilled water, and stir constantly until the qiu- nine and citric acid are dissolved. Last- ly evaporate the solution on a water bath at a temperature not exceeding 60 deg. C. and spread it on plates of glass so that when dry the salt may be ob- tained in scales. Plates of porcelain may be used as well as plates of glass for the final dry- ing. This drying may be facilitated by a temperature of not to exceed 35 deg. C.—V. S. P. 1890. The product contains at least 11^2 p. c. of quinine. It should be preserved in well-stoppered bottles protected from light. The preparation of the Brit. PHARMACEUTICAL PREPARATIONS. 217 Pharm. contains about 15 p. c. of qui- nine. The product is in transparent scales of a reddish brown color and slowly soluble in water. The commercial cit- rate of iron and quinine, however, is in greenish-yellow scales readily soluble, due to the addition of ammonia, and such a preparation is now recognized by the U. S. P. under the name soluble iron and quinine citrate (which see). Iron and Quinine Citrate, Soluble. This is the -^reparation sold commer- cially under the name "citrate of iron and quinine." It is prepared similarly to iron and quinine citrate (which see), quinine and citric acid being mixed with water and stirred into warm iron cit- rate soluton until dissolved. Then add gradually with constant stirring 4 fluid- ounces, or a sufficient quantity of am- monia water (10 p. c), so that after the addition of each portion of the latter, the precipitated quinine will be redis- solved and the liquid acquire a greenish- yellow tint. Lastly evaporate the solu- tion on a water bath at a temperature not exceeding 60 deg. C. to the consist- ence of syrup, and spread it on glass (or porcelain) plates to dry in scales. — U. S. P. 1890. This drying on the plates should be facilitated by the use of a temperature of about 35 deg. C. The product is in greenish-yellow scales containing at least 11^ p. c. of ouinine. It should be preserved in well- stoppered bottles protected from light. Iron, Quinine and Strychnine Citrate. This may be prepared like iron and strychnine citrate (which see), but the strychnine and citric acid should be increased to 20 grains each, and to the mixed iron and strychnine solutions add a solution of 225 grains of quinine (al- kaloid) and 60 gr. citric acid in 1 fluid- ounce of distilled water. Evaporate and scale the product like the other scale salts, Iron and Strychnine Citrate. Iron and ammonium citrate.av.oz. 4 Strychnine (alkaloid) gr. 18 Citric acid , gr. 18 Distilled water fl.oz. 5 Dissolve the citrate in 4 fluidounces of the water, and the strychnine and citric acid together in 1 fluidounce of water. Mix the two solutions, evap- orate the mixture by means of a water bath at a temperature not exceeding 60 deg. C. to the consistence of syrup, and spread on glass (or porcelain) plates to dry in scales. The drying on the plates may be fa- cilitated by the use of a temperature of 35 deg. C. The product, which contains 1 p. c. of strychnine, should be preserved in well- stoppered bottles protected from light. — U. S. P. 1890. Iron (Ferrous) Sulfate, Dried or Ex- siccated. Take any convenient quantity of pure ferrous sulfate, crystal, in coarse pow- der, allow the salt to effloresce at a temperature of about 40 deg. C. in dry air and then heat it in a porcelain dish on a water bath, constantly stirring, until for every 100 parts by weight of crystals used there shall be 64 to 65 parts by weight of dried salt. Lastly reduce the residue to fine powder and transfer at once to perfectly dry, well- stoppered bottles. — U. S. P. 3 grains of the dried salt are about equal in strength to 5 grains of the crys- talline. Iron (Ferrous) Sulfate, Granulated. (Precipitated Iron Sulfate, U. S. P. 1880.) Ferrous sulfate, pure, crys- tal av.oz. 4 Diluted sulfuric acid m. 100 Alcohol fl.oz. 1 Distilled water fl.oz. 4 Dissolve the iron salt in the distilled water, previously heated to boiling, add the diluted acid, and filter the solution while hot. Evaporate the solution im- mediately in a tared porcelain capsule 218 STANDARD FORMULARY OF on a sand bath until it weighs 6 av.- ounces. Then cool it quickly, under constant stirring, transfer the product to a glass funnel stopped with a plug of absorbent cotton, and when it has drained thoroughly pour upon it the alcohol. When this also has drained, spread the crystalline powder on bibu- lous paper, dry it quickly in the sun- light or in a dry room at the ordinary temperature and transfer it at once to perfectly dry, well-stoppered bottles. — U. S. P. This preparation has the same com- position as the crystal salt. According to the U. S. P. 1880, it was made by dissolving 6 av. ounces of pure ferrous sulfate in 10 fluidounces of distilled water previously mixed with 1 fluidram of sulfuric acid, filtering, al- lowing to cool, adding the filtrate to an equal volume of alcohol, setting aside for 24 hours, collecting the precipitate on a filter, washing it with alcohol, and drying it Jellies. The form of jelly has been advised as a convenient and easy method of ad- ministering medicines, especially fixed oils, e. g., cod-liver and castor oils. The following general formula has been rec- ommended by Prof. Parrish and W. C. Bakes : Oil av.oz. 4 Honey or simple syrup. . .av.oz. 2 Acacia, powder av.oz. 1 Russian isinglass gr. 150 Orange flower water fl.oz. zY\ Dissolve the isinglass in 2 fluidounces of the water by the aid of heat, re- placing the water as it evaporates, trit- urate the other ingredients with the re- mainder of the water, in a warmed mor- tar, to a homogeneous paste, add the hot isinglass solution, stir the mixture as it cools, and set aside to gelatinize. Other flavoring waters may be sub- stituted for the orange flower water. In the case of cod-liver jelly, cherry- laurel or bitter almond water, somewhat diluted with plain water, may be used. Hager uses this formula: Oil av.oz. 4 Gelatin, best gr. 150 Aromatic tincture m. 50 Simple svru" fl.oz. i l / 2 Distilled water fl.oz. 2 Dissolve the gelatin in the water by the aid of heat, restoring water lost by evaporation, add the syrup, then the oil and tincture. Jelly, Castor Oil. See under heading Jellies. Jelly, Cod-Liver Oil. See under heading Jellies. Jelly, Currant. See Paste, Currant. Jelly, Zinc. See Gelatin, Zinc. Juice of Belladonna. (Succus Bella- donna}.) Bruise the fresh leaves and young branches of Atropa Belladonna, press out the juice, to every 3 volumes, add one of alcohol, set aside for 7 days, and filter.— Brit. Pharm. Juice of Broom. ( Succus Scoparius.) Bruise fresh broom tops, press out the juice, to every 3 volumes add one of alcohol, set aside for 7 days, and filter. —Brit. Pharm. Juice, Calendula. (Succus Calendu- la}.) Bruise the entire fresh plant gathered while flowering, express the juice, add one-seventh its volume of alcohol, set aside for several days, and strain. Juice of Conium. (Succus Conii. — Juice of Hemlock.) Bruise the fresh leaves and young branches of Conium maculatum, press out the juice, to every 3 volumes add one of alcohol, set aside for 7 days, and filter.— Brit. Pharm. Juice of Dandelion. (Succus Tar- axaci.) Bruise fresh dandelion root, press out the juice, to every 3 volumes add one of alcohol, set aside for 7 days, and filter.— Brit. Pharm. Juice of Digitalis. Bruise fresh digitalis leaves, express PHARMACEUTICAL PREPARATIONS. 219 the juice, to every 3 volumes add one volume of alcohol, set aside for 7 days, and filter. — Brit. Form. Juice, Elder. (Succus Sambuci In- spissatus. — Roob Sambuci. — Sy- rupus Sambuci. — Elder-Berry Syrup or Juice.) Take any desired quantity of freshly gathered elder berries, heat, with con- stant stirring, until they burst open, then strain through a hair sieve and express the residue; evaporate the juice to a rather thick extract, and add to this powdered sugar in the proportion of 1 part by weight to every 9 parts by weight of the extract. — Austr. Pharm. All application of heat must be over a water bath. Juice of Henbane. (Succus Hyoscy- ami.) Bruise the fresh leaves, flowering tops and young branches of Hyoscyamus niger, press out the juice, to every 3 volumes add one of alcohol, set aside for 7 days, and filter. — Brit. Pharm. Juice, Huckleberry. (Succus Myrtil- li Inspissatus.) Huckleberries, fresh av.oz. 16 Water fl.oz. 8 Sugar av.oz. 1^ Heat the berries in a porcelain or enameled iron evaporating dish, on a boiling water bath, for one hour, and express. Heat the residue for an hour with the water, express again, mix the two liquids, add the sugar and heat until dissolved. Strain through a fine cloth and then evaporate on a water bath to thick extract, stirring constantly meanwhile. This is used sometimes, in domestic practice, in the treatment of the diar- rhea of children. — D. Juice, Juniper. (Roob Juniperi.— Succus Juniperi Inspissatus. — Juniper-Berry Syrup.— Syrupus Juniperi.) juniper berries, fresh, bruised av.oz. 8 Water, hot fl.oz. 31 Mix, stir frequently during 12 hours, express, and evaporate the liquid to a thin extract,— Germ. Pharm, In the absence of fresh berries this preparation may be made from the or- dinary dried berries, by the use of a larger proportion of water and a longer period of maceration. Juice, Lemon, Artificial. When lemon juice is not readily ob- tainable, the following may be employed instead : Citric acid gr. 525 Distilled water fl.oz. 14 Oil of lemon drops 10 Alcohol fl.oz. i l / 2 Dissolve the acid in the water and the oil in the alcohol, mix the two solutions and filter.— H. Juice, Lime, and Pepsin. I. Glycerite of pepsin fl.oz. 8 Lime juice fl.oz. 12 Mix and filter if necessary. Each fluidram represents about 2 gr. of pep- sin (1 :300o). — N. F. II. Pepsin, pure gr. 128 Water fl.oz. 1 Lime juice fl.oz. 2 Simple elixir, to make fl.oz. 16 Mix, dissolve by agitation, and filter. Jutes. Medicated jute is used sometimes as a surgical dressing instead of medicated cotton. The so-called raw or unbleached jute as well as the bleached is used for making the medicated jute, but the bleached, being more absorbent, is pre- ferred and is the only kind mentioned in the formulas here given. Bleached jute may be prepared from the un- bleached in the same manner as absorb- ent cotton and gauze are made from the raw material. In general jute is less absorbent than cotton, but the former possesses the ad- vantage of being more porous and not packing together so closely. Medicated jute is usually prepared similarly to medicated cotton and gauze ; the material is saturated with the medi- cating liquid by kneading, subsequent ex- | pressing to a weight double that of the 220 STANDARD FORMULARY OF original material, drying, and packing in boxes, packages, etc., like medicated cotton. Jute, Carbolated. I. 5 p. c. iop. c. Carbolic acid, crystal av.oz. 1^4 av.oz. 2^4 Distilled water, fl.oz. J fl.oz. 6 Alcohol fl.oz. 19 fl.oz. 19 Bleached jute. .av.oz. 16 av. oz. 16 Dissolve the acid in the alcohol and water, saturate the jute with this solu- tion by kneading, express to a weight of 32 av. ounces, and dry in the air. — D. IT. Process of Muennich : Carbolic acid crystal av.oz. . Y^ Spermaceti av.oz. 1 Resin av.oz. 2 Alcohol, 95 p. c fl.oz. 15 Bleached jute av.oz. 10 Dissolve the acid, resin and spermaceti in the alcohol, impregnate the jute with all of this solution, slightly warmed, weight down in a warm place for sev- eral hours, and dry in the air. — D. This makes a yY 2 per cent. jute. III. Rosenwasser's process: Carbolic acid, crystal av.oz. 1 Paraffin av.oz. 1 Resin av.oz. 4 Bezin fl.oz. 30 Jute av.oz. 10 Dissolve the acid, paraffin and resin in the benzin and saturate the jute with all of this solution if a 10 p. c. jute is wanted, or with half of it if a 5 p. c. jute is wanted. This is a cheap process owing to the use of the cheap solvent. Jute, Iodoform. Iodoform av.oz. 1 Resin gr. 130 Castor oil gr. 130 Ether, stronger fl.oz. g]/ 2 Alcohol fl.oz. s T A Bleached jute av.oz. 10 Dissolve the iodoform, resin and oil in the mixed ether and alcohol, impreg- nate the jute with all of this liquid, and dry by exposure to the air, under ex- clusion of daylight. This makes a 10 per cent. jute. — D. Jute, Mercuric Chlorid. (Corrosive Sublimate or Sublimated Jute.) Mercuric chlorid gr. 22 Sodium chlorid av.oz. 2 Glycerin av.oz. 1 Distilled water fl.oz. uy 2 Bleached jute av.oz. 10 Dissolve the two chlorids in the water, add the glycerin, impregnate the jute with all of this liquid, and dry at a temperature of 25 to 30 deg. C. — D. This makes a T / 2 per cent. jute. A 1 in 1000 jute may be prepared from 4H gr. of mercuric chlorid, 175 gr. of sodium chlorid, 1 av. ounce of glycerin. 12 fluidounces of water and 10 av. ounces of jute. Jute, Salicylated. 5p.c. 10 p. c. Salicylic acid... av.oz. i*4 av.oz. 2 l /> Castor oil av.oz. y 2 av.oz. 1 Alcohol fl.oz. 26y 2 fl.oz. 24^ Bleached jute, .av.oz. 16 av.oz. 16 Dissolve the acid and oil in the alco- hol, saturate the jute with this solution, express to a weight of 32 av. ounces, and dry at a temperature of 25 to 30 deg. C— D. Kneipp's Remedies, Pastor. The following are the formulas given for these remedies by Landauer and Oberhauser (in Pharm. Ztg. 1893) and in Holfert's Arzneimittelnahmen : Breast and Cough Tea (Brust und Husten-Thee). — Coltsfoot leaves, 8 parts ; nettle leaves, 4 parts ; equisetum, 4 parts; fennel, 2 parts; juniper berries, 2 parts ; snake plantain, 2 parts ; mallow flowers, 2 parts ; linden blossoms, 2 parts ; mullein flowers, 1 part ; fenu- greek, 1 part. There is also a liquid form. Felon or Secretive Oil (Malefiz Oel — Ausscheidungs Oel). — Croton oil, 1 part ; sweet almond oil, 6 parts. Strengthening, Blood-Purifying and Laxative Tea (Staerkungs, Abfuehr- ungs-und Blutreinigungs-Thee.) . — Elder flowers, 4 parts ; elder leaves, 4 parts ; dwarf elder root, 4 parts ; sandalwood, 4 parts: buckthorn bark, 4 parts; mis- PHARMACEUTICAL PREPARATIONS. 221 tletoe, 4 parts ; sloe blossoms, 2 parts ; strawberry leaves, 2 parts ; nettle leaves, 2 parts : juniper tops, 1 part. Stomach Drops or Consoler (Magen- trost). — St. Johnswort leaves and flow- ers, 30 parts; milfoil, 10 parts; juniper berries, 10 parts; dog-rose (hips), 10 parts ; gentian root, 10 parts ; worm- wood, 5 parts ; buckbean, 5 parts ; equi- setum, 5 parts ; eye-bright, 5 parts ; little centaun-, 5 parts ; peppermint oil, 1 part ; alcohol, 60 p. c, 1,000 parts. • Searcher, or Tonic Laxative (Wuehl- huber). — This may be used as "tea" (species) or as powder. No. 1 is com- posed of aloes, 8 parts ; fenugreek, 8 parts; fennel, 25 parts; juniper berries, 25 parts. No. 2 is composed of aloes, 1 part; fenugreek, 1 part; fennel, 2 parts; juni- per berries, 3 parts, and dwarf elder, 3 parts. Wuehlhuber pills are made of pow- dered wuehlhuber massed with acacia mucilage, each weighing i l / 2 gr. Eye-Bright (Augentrost).— Extract of aloes, 1 part ; fennel, 50 parts ; eye- bright, 50 parts ; alcohol, 100 parts ; wa- ter, 400 parts. Dropsy and Kidney Tea (Wasser- sucht und Nieren-Thee). — Equisetum, 8 parts; dog-rose, 4 parts; rosemary, 2 parts ; elder root, 2 parts ; sassafras, 2 parts; rue, 1 part; buckbean, 1 part; uva ursi, 1 part; mistletoe, 1 part; san- dalwood, 1 part; juniper berries, 1 part. Kneipp's Cathartic Pills; Genuine Wuerzburger Rhubarb Pills (Aechte Wuerzburger Rhabarber Pillen— Abfiihr Pillen). — Rhubarb, 40 grams; extract of aloes, 40 grams ; extract of rhubarb, 10 grams; soap, 10 grams; juniper berries, 3 grams : fenugreek, 3 grams ; dwarf elder, 3 grams; fennel, 3 grams. Make into 600 pills. There is also a Wuerzburger rhubarb syrup for children and others who can- not take the pills. Lumbago Plaster (Hexenschuss Pflaster) . — Dispense burgundy pitch plaster, Pitch Plaster (Pech Pflaster).— This is the regular pitch plaster, such as that of the oharmacopeias. Wormwood Pills (Wermuth Pillen). — Powdered wormwood herb made into pills with acacia mucilage, each weigh- ing iy 2 gr. Calendula Ointment (Calendula Sal- be). — Simple ointment impregnated with flower and herb of calendula. Reise Tropfen. — This does not con- tain cinchona, but is composed of tinc- tures of chamomile, wormwood, little centaury and arnica, using fresh drugs. Blood-Forming Bone Meal. — Iron lac- tate, 2 parts ; manganese lactate, 1 part ; manganese phosphate, 1 part, and bone meal, freshly calcined to whiteness, 200 parts. Bone Meal is made by calcining ox bones. Gray Bone Meal is a mixture of equal parts of white and black bone meal and powdered olibanum. White Bone Meal is calcium phos phate. Black Bone Meal is animal charcoal. Clay Ointment (Lehm-Salbe) is fine bole [probably like terra alba] made into an ointment-like mixture with water. Veilchen Blaetter and Wurzel (or vi- olet) used in Kneipp's preparations are the leaves and root of Viola odorata. Sage Oil (Salbei-Oel), St. Johnswort Oil (Johanniskraut-Oel), Rue Oil (Rauten-Oel) and other oils are infused oils prepared from the leaves like in- fused oil of henbane. Tinctures. — All tinctures for Kneipp's preparations are to be prepared as far as possible from the freshly-gathered plant parts. Tape Worm Remedy is oleoresin of male fern and castor oil in capsules. Worm Chocolates are troches of san- tonin with chocolate as the vehicle. Lard. (Adeps. — Adeps Suillus. — Ax- ungia Porci.) The adipose tissue adhering to the 222 STANDARD FORMULARY OF kidneys, mesentery and omentum of the hog is considered the source of the best lard. This is freed from flesh, then cut into small pieces, removing, as far as possible, all bloody matter and the mem- branous tissue. Then heat in a tinned copper, porcelain, or enameled-iron dish on a water bath until the fat is about all melted, and then strain. The U. S. P. describes lard as the prepared internal fat of the abdomen of the hog, Sus scrofa, purified by wash- ing, melting, and straining. The Brit. Pharm. describes it as the purified fat of the hog, Sus scrofa, and gives the following process: From the perfectly fresh fat of the abdomen of the hog, remove as much of the external membranes as possible, suspend the fat so that it shall be free- ly exposed to the air for some hours, cut it into small pieces, reduce these to a uniform mass in which the mem- branous vesicles are completely broken, by beating in a mortar or by some similar process, put the mass thus pro- duced into a vessel surrounded by warm water, heat to a temperature not exceeding 57 deg. C. until the fat has melted and separated from the mem- branous matter, and strain. The fat may be conveniently and quickly reduced to small pieces by grinding in a food chopper. The small- er the pieces the more quickly will the lard be melted out and the more nearly odorless, therefore, will it be. The U. S. P. directs that lard should be kept in well-closed vessels, impervi- ous to fat, and in a cool place. Lard, Anhydrous or Dehydrated. Lard may be made perfectly anhy- drous by heating on a water bath for about 30 minutes with about one-twelfth its weight of anhydrous or dry sodium sulfate in fine powder, then filtering through paper, using some system of hot filtration to maintain the lard in a liquid state. Lard prepared in this manner re- mains "sweet" much longer than the ordinary lard. — D. Lard, Benzoinated. (Benzoated .Lard.) Lard av.oz. 16 Benzoin, coarse powder gr. 140 Add the benzoin to the lard and mix thoroughly ; then melt the lard by means of a water bath, and, stirring, frequent- ly, continue the heat for 2 hours, cov- ering the vessel and not allowing the temperature to rise above 60 deg. C. Strain the liquid through muslin and stir occasionally while it cools. When benzoinated lard is to be kept or used during warm weather, it may be hardened somewhat by adding 5 per cent, (or more if necessary) of white wax.— U. S. P. The addition of stearin or Japan wax has also been suggested for slightly hardening lard and making it more suit- able for use in summer time or in warmer climates, but white wax is to be preferred. Benzoinated lard of the Brit. Pharm. is made from 16 av. ounces of lard and 210 grains of powdered benzoin, heat- ing on a water bath for 2 hours, stir- ring frequently, then straining to re- move the benzoin, and stirring the lard until cold. Benzoated lard of the Austr. Pharm. is made like that of the Brit. Pharm., but using 280 grains of powdered Siam benzoin. Benzoated lard of the Germ. Pharm. is made melting, on a water bath, 1 av.pound of lard, and dissolving 71 grains of benzoic acid, from benzoin, in it. Lard may be benzoinated most conve- niently and satisfactorily in the follow- ing manner: Benzoin, coarse powder av.oz. 1 Ether fl.oz. 2 Castor oil, to make av.oz. Y* Macerate the benzoin in the ether for 24 hours, agitating frequently, filter, to the filtrate add one av.ounce of the oil. PHARMACEUTICAL PREPARATIONS. 223 carefully distil off the ether, and add the remainder of the oil to the residue. Instead of the ether, 4 fluidounces of pure wood alcohol may be used. Then melt together, on a water bath, 1 av. ounce of white wax and 3 av. pounds of lard, and incorporate with this the above oil solution of benzoin. Anhy- drous lard is to be preferred for this mixture. Lards, Factitious. Quite a number of fats of animals, frequently called "greases," are demand- ed of pharmacists. Some of these lards or fats cannot be obtained, or at least with great difficulty, and as a rule other substances or mixtures of other sub- stances are substituted for them. The formulas given herewith will be found acceptable for preparing these "greases." Badger Fat (Dachs-Fett). Ordinary lard is dispensed. Bear's Fat or Grease (Baeren-Fett). Olive oil, yellow fl.oz 4 Lard av.oz. 12 Benzoic acid, powder gr. 60 Melt the lard at a gentle heat, add the oil and incorporate the acid by stirring until uniform. Ordinary lard is most commonly given for it. Castor Fat or Grease (Biebergeil-Fett). Lard av.oz. 1 Beef suet av.oz. I Burgundy pitch av.oz. 1 Castor, powder gr. 20 Melt all together at a gentle heat, strain, and stir till cool. A common substitute is to use lard with a few drops of tincture of castor added. Cat's Fat or Grease (Katzen-Fett). Lard av.oz. 4 Oil of valerian drops 4 Dog's Fat or Grease (Hunde-Fett). Olive oil, yellow fl.oz. 1 Lard av.oz. 3 or 4 Lard is often dispensed for it, but its consistence is too firm. Eel Fat or Oil (Aal-Fett). Cod-liver oil is usually dispensed for it. Hager recommends mixture of 9 parts each of sweet almond and castor oils and 2 of cod-liver oil. Fox Fat or Grease (Fuchs-Fett). Dispense lard. Goose Grease or Oil (Gaense-Fett). Olive oil fl.oz. 1 Lard av.oz. 4 Oil of nutmeg or mace drops 4 This is also dispensed without the fla- voring oil. Monkey Fat or Grease (Affen-Fett). Lard is dispensed for this. Rabbit Fat (Hasen-Fett). Olive oil, yellow av.oz. 2 Z A Lard av.oz. 2 Beef suet av.oz. 2 Yellow wax av.oz. 1 Resin cerate is sometimes dispensed for it, but the above is a better substi- tute. Skunk Oil or Grease. Lard oil fl.oz. 8 Lard av.oz. 8 Animal oil, Dippel's drops 5 Snake Fat (Schlangen-Fett). Dispense cod-liver oil. Stork Fat (Storchen-Fett). Dispense lard. Wild Cat Fat or Grease (Wild Katzen- or Kater-Fett). Dispense lard. Wolf Fat (Wolfs-Fett). Dispense lard. Other lards may be found under head- ing Suets, which see. Lead Tannate, Pasty or Pultiform. (Unquentum or Linimentum ad Decubitum Autenriethii.) Oak bark, cut or bruised. . .av.oz. 8 Alcohol fl.oz. 1 Water, solution of lead sub- acetate, each sufficient Boil the bark for one-half hour with sufficient water so that after straining, the decoction will measure 40 av.ounces. Filter this, and to the filtrate add the solution, stirring constantly, until no more precipitate is formed. Collect this on a filter, allow to drain, transfer the damp, pasty mass (amounting to about 12 av.ounces) to a wide-mouthed bottle, 224 STANDARD FORMULARY OF Ligatures. add the alcohol, and shake well. — Germ. Form. See Catgut Ligatures and Silk Liga- tures. Linctus (also called Look, Loch, Lo- boch, Lincture, Lambative, etc.) The preparations known as linctuses are now practically obsolete. They were sweetened, of the consistency of honey and intended to be licked off a spoon. Only one linctus, the common or white linctus. is mentioned in this work; see Emulsion of Almond. Liniment, ABC. I. The ordinary or original is made as follows : Liniment of aconite, Brit. Pharm fl.oz. i Liniment of belladonna, Brit. Pharm fl.oz. i Liniment of chloroform, Brit. Pharm fl.oz. i A modification, which makes a clear mixture, and which is now largely used, is as follows: II. Liniment of aconite, Brit. Pharm fl.oz. 5 Liniment of belladonna, Brit. Pharm fl.oz. 5 Chloroform fl.oz. 2 ^ Camphor gr. 210 Glycerin fl.oz. 2 Dissolve the camphor in the mixed chloroform and liniments, and add the glycerin. Liniment of Aconite. I. Aconite root, No. 40 pow- der av.oz. io^4 Camphor gr. 250 Alcohol, to make fl.oz. 16 Extract the drug by percolation with alcohol so that the percolate when mixed with the camphor, will make 16 av.- ounces; dissolve the camphor by agita- tion. — Brit. Pharm. II. Aconite root, powder av.oz. 4 Glycerin fl.dr. 2 Alcohol sufficient Extract the drug by maceration and slow percolation to obtain 16 fluidounces of percolate, distil off 12 fluidounces, evaporate the residue to 12 fluidrams, and to this add the glycerin and 2 fluid- drams of alcohol. — Eclectic. Liniment of Aconite and Chloroform. Fluid extract of aconite (U. S. P.) fl.dr. 6 Alcohol fl.dr. 10 Chloroform fl.oz. 2 Soap liniment fl.oz. 12 — N. F. See also Liniment, Chloroform, Com- pound, which also contains chloroform and aconite. II. Castor oil fl.oz. 1 Chloroform fl.oz. 1 Ammonia water fl.oz. 1 Tincture of aconite fl.oz. 1 Soap liniment fl.oz. 4 — Eclectic. Liniment of Aconitine, Compound. (Anodyne Pomade.) Aconitine gr. 1 Glycerin fl.dr. 1 Hydrocyanic acid fl.dr. 1 Triturate the aconitine with the glyc- erin until well mixed, then add the acid, mix thoroughly, and put into a well- stoppered vial. In preparing this, care should be taken not to inhale any of the mixture, and after adding the acid, the mixture should be bottled as quickly as possi- ble. — Eclectic. This is applied by means of a camel's hair pencil to parts affected with neu- ralgia. Liniment of Amber Oil, Compound. (Linimentum Succini Composi- tum.) Oil of amber, rectified fl.oz. 1 Oil of stillingia fl.oz. I Oil of lobelia fl.dr. 3 Olive oil fl.oz. 2 — Eclectic. PHARMACEUTICAL PREPARATIONS. 225 Liniment, Ammonia. (Volatile, Hartshorn, Ammoniacal or Com- mon Liniment.) I. Ammonia water, 10 p. c fl.oz. 10^2 Alcohol fl.oz. iy 2 Cotton seed oil fl.oz. 17 Oleic acid fl.oz. 1 Mix all by agitation in a bottle which should be well-stoppered. This liniment should be freshly pre- pared when wanted. — U. S. P. Sometimes other oils are used instead of cotton seed oil; lard oil is excellent. The oleic acid for this purpose need not necessarily be the purified article; the crude will serve as well. Stearic acid may also be used instead of it. Liniment of ammonia of the Brit. Pharm. is made from 1 fluidounce each of ammonia water, 10 p. c. and sweet almond oil and 2 fluidounces of olive oil. The preparation of the Germ. Pharm. is made from 3 parts by weight of olive oil, 1 of poppy-seed oil, and 1 of 10 p. c. ammonia water. II. Cine. Acad, of Pharm. formula for liquid oleate of ammonium or harts- horn liniment which is an improvement on the U. S. P. formula for ammonia liniment and is intended to be used in place of the latter: Ammonia water av.oz. 10 Lard oil av.oz. 9 Cottonseed oil av.oz. 11 Mix by agitation in a bottle. The ingredients may be mixed if de- sired in the same proportion by fluid measure. The ammonia water must be of the strength of the U. S. P., viz., 10 per cent. This preparation is of about the same strength as liniment of ammonia U. S. P. (which see) and contains about 57 per cent, of ammonium oleate. Liniment of Ammonia, Camphorated. See Liniment of Camphor, Ammoni- ated. Liniment of Ammonia, Compound. (Granville's Counter-irritant Lotion.) I. Stronger : Stronger ammonia water. . .fl.oz. 5 Spirit of camphor fl.oz. 2 Oil of rosemary fl.dr. 1 Alcohol to make fl.oz. 8 II. Weaker: Stronger ammonia water. . .fl.oz. 5 Spirit of camphor fl.oz. 3 Oil of rosemary fl.dr. 2 Alcohol to make fl.oz. 10 Liniment of Ammonium Iodid. Iodin gr. 30 Oil of rosemary fl.dr. 2 Oil of lavender flowers. . .fl.dr. 2 Camphor gr. 240 Ammonia water, 10 p. c fl.dr. 14 Alcohol to make fl.oz. 16 Dissolve the iodin, the oils and the camphor, in 12 fluidounces of alcohol, then add the ammonia water and lastly, enough alcohol to make 16 fluidounces. On standing, the liquid will become colorless, and there will, usually, be a slight precipitate, which may be sepa- rated by filtration. — N. F. Liniment, Arnica. This formula may be used : Tincture of arnica fl.oz. 4 Soap liniment fl.oz. 12 Liniment, Belladonna. I. Camphor gr. 365 Fluid extract of belladonna root, to make fl.oz. 16 Dissolve the camphor in about 13 fluidounces of the fluid extract and then add enough of the latter to make 16 fluidounces. — U. S. P. II. Liquid extract of belladonna (corresponding practically to fluid extract of bella- donna root, U. S. P.)... fl.oz. 8 Camphor gr. 365 Distilled water fl.dr. 13 Alcohol, to make fl.oz. 16 Dissolve the camphor in 5 fluidounces of alcohol, then add the extract, water, and remainder of the alcohol. — Brit. Pharm. The U. S. P. formula is the preferable one. 226 STANDARD FORMULARY OF Liniment, Black. (Linimentum Ni- grum.) Olive oil fl.oz. 6 Oil of turpentine fl.oz. 2 Sulfuric acid • • . fl-dr. 4 Add the acid very gradually, and with constant stirring, to the olive oil, allow to cool, and add the oil of turpentine.— Eclectic. Liniment, Cajeput, Compound. Oil of cajeput fl.oz. 2 Oil of sassafras fl.oz. 2 Oil of hemlock ..fl.oz. 2 Soap sufficient Mix together and form a liniment. — Eclectic. The above are the directions as they are given ; presumably about ^2 av.- ounce of powdered castile soap should be sufficient. Liniment, Camphor. (Camphorated Oil. — Camphor Embrocation.) I. Camphor, coarse powder. ..av.oz. 6 Cottonseed soil av.oz. 24 Mix in a bottle or flask, apply a gen- tle heat on a water bath, loosely stop- pering the bottle, and agitating from time to time until the camphor is dis- solved.— U. S. P. Liniment of camphor of the Brit. Pharm. is made from 6J4 av.ounces of camphor and 24 fluidounces of olive oil. Camphorated oil of the Germ. Pharm. is made from 1 av.ounce of camphor and 9 av.ounces of olive oil. There is also a stronger camphorated oil in the Germ. Pharm. made from 1 av.ounce of camphor and 4 av.ounces of olive oil. II. Camphor av.oz. V/2 Chloroform . % fl.dr. 2 Olive oil fl.oz. 2 Mix and dissolve the camphor by agi- tation. Liniment of Camphor, Ammoniated. (Compound Liniment of Cam- phor.) Camphor av.oz. 2 Oil of lavender flowers m. 50 Stronger ammonia water. . . .fl.oz. 4 Alcohol, to make fl.oz. 16 Dissolve the camphor and oil in to fluidounces of alcohol, add the water gradually with constant agitation, and then add the remainder of the alcohol. —Brit. Pharm. Ammonio-camphorated liniment of the Germ. Pharm. is made from 1 av.ounce each of 10 p. c. ammonia water and poppy-seed oil (cottonseed oil may be used for this) and 3 av.ounces of cam- phorated oil (G. P.). Camphorated ammonia liniment of the Norw. Pharm. is made from 1 part of camphorated oil (1 of camphor and 4 of olive oil), 2 of rapeseed oil and 2 of ammonia water. The preparation of the Dan. Pharm. is made from 1 of camphor, 14 of rapeseed oil and 5 of ammonia water. Liniment of Camphor, Compound. (Comp'd Tincture of Camphor.) . .av.oz. . .av.oz. ...fl.oz. ...fl.oz. ...fl.dr. ...fl.dr. ...fl.dr. Y2 fl.oz. 16 Camphor Capsicum, powder . . Oil of origanum .... Oil of hemlock Oil of sassafras .... Oil of cajeput Oil of turpentine ... Alcohol Mix, macerate for 14 days, and filter in a well-covered funnel. — Eclectic. This is recommended for both exter- nal and internal use. It is used in chron- ic rheumatism, bruises, sprains, chil- blains, lameness, etc. In ordinary cases, rub in well several times, then wrap in warm flannel. Internally take 20 drops on sugar. In severe and obstinate cases, bathe the parts as directed, apply flan- nel, and keep the latter moist with the liniment. In case of toothache, apply a small quantity of the liquid to the hollow of the tooth on a piece of cot- ton. If the face is swollen, apply some of the liquid externally. The Brit. Pharm. recognizes a Lini- ment of Camphor, Ammoniated, which is also known as compound liniment of camphor. Liniment, Cantharids. Cantharides, No. 60 powd.. av.oz. 2 x /i Oil of turpentine, to make. fl.oz. 16 PHARMACEUTICAL PREPARATIONS. 227 Digest the cantharides with 16 fluid- ounces of oil, in a closed vessel, by means of a water bath, for 3 hours ; then strain, and add enough oil through the strainer to make the liniment meas- ure 16 fluidounces.— U. S. P. 1880. Liniment, Capsicum, Compound. Tincture of capsicum fl.oz. 8 Tincture of opium fl.oz. 1^2 Ammonia water fl.oz. i l / 2 Oil of origanum fl.oz. 1 Oil of cinnamon fl.oz. ]/ 2 Spirit of camphor fl.oz. y 2 — Eclectic. Liniment, Chloroform. Chloroform fl.oz. 4^4 Soap liniment fl.oz. 11 *4 Or mix 3 fluidounces with 7 fluidounces. — U. S. P. Liniment of chloroform of the Brit. Pharm. is made from equal volumes of chloroform and liniment of camphor (B. P.). Liniment, Chloroform, Compound. (Chloroform and Aconite Lini- ment.) Chloroform fl.oz. 2 Tincture of aconite fl.oz. 2 Soap liniment fl.oz. 12 See also Liniment of Aconite and Chloroform. Liniment of Croton Oil. (Linimen- tum Tiglii or Crotonis.) Croton oil fl.dr. 4 Oil of cajeput fl.dr. 14 Alcohol fl.dr. 14 — N. F. and Brit. Pharm. Croton oil liniment was formerly made (old London Pharm.) from 1 vol- ume of croton oil and 7 of oil of tur- pentine. Liniment, Croton Oil, Compound. Croton oil fl.oz. 1 Oil of sassafras. fl.oz. 1 Oil of turpentine fl.oz. 1 Olive oil fl.oz. 2 — N. F. Liniment, G. D. D. Tincture of aconite fl.dr. 6 l / 2 Chloroform fl.dr. 6 l / 2 Spirit of camphor fl.dr. 6V2 Oil of thyme m. 100 Soap liniment, to make. .. .fl.oz. 16 — New York Hospitals. IS Liniment, Iodin. Iodin gr. 960 Potassium iodid gr. 360 Glycerin fl.dr. 4 Water fl.oz. 1 Alcohol, to make fl.oz. 16 Mix 12 fluidounces of alcohol with the other ingredients, and dissolve the solids by agitation. Then add enough alcohol to make 16 fluidounces. This is modeled after the formula of the Brit. Pharm. 1885, which differed from the above only in directing 16 fluidounces of alcohol instead of simply enough to make 16 fluidounces. The preparation of the Brit. Pharm. 1898, in which the title has been changed to "strong solution of iodin," is made from 900 grains of iodin, 540 grains of po- tassium iodid, 15 fluidrams of water, and 14^ fluidounces of alcohol. Liniment of Ipecac. Ipecac, powder gr. 120 Sweet oil ...fl.dr. 2 Lard av.oz. l / 2 — Eclectic. Liniment of Lead Subacetate. (Lini- mentum Plumbi Subacetatis.) Solution of lead subacetate. fl.oz. $y 2 Cottonseed oil . .fl.oz. 10^2 — N. F. Appendix and — U. S. P. 1880. Liniment, Lime. (Carron Oil. — Lini- mentum Calcis.) Lime water, linseed oil, raw, each, equal parts by volume. Mix well by agitation. — U. S. P. The U. S. P. 1880 used cottonseed oil instead of the linseed oil. The Brit. Pharm. uses equal volumes of lime wa- ter and olive oil. Liniment, Menthol. Martindale's formula : Menthol gr. 360 Chloroform fl.oz. 1 Alcohol, to make fl.oz. 4 Liniment of Mercury. (Linimentum Hydrargyri.) Me"rcury ointment, 50 p. c. av.oz. 1 Stronger ammonia water.... m. 160 Camphor liniment sufficient Add to the water enough liniment iO 228 STANDARD FORMULARY OF make V/2. fluidounces : triturate the oint- ment with enough liniment to make V/2 fluidounces; mix the two liquids.— Brit. Pharm. Liniment, Mott's. Chloroform • • . fl.oz. 2 Tincture of iodin fl.oz. 2 Tincture of aconite fl.oz. 2 Ammonia water fl.oz. 2 Soap liniment fl.oz. 8 Add the chloroform and tincture of aconite to the soap liniment, then add the tincture, shake well, and add the ammonia water. — Xew York Hospitals. Liniment of Mustard. (Linimentum Sinapis.) Volatile oil of mustard fl.dr. 2^ Camphor gr. 200 Castor oil fl.oz. 1 Alcohol •• fl.oz. 6 l / 2 Dissolve the camphor in the alcohol and add the two oils.— Brit. Pharm. Liniment of Mustard, Compound. Oil of mustard, volatile fl.dr. 2 Fluid extract of mezereum.. fl.dr. 13 Camphor av.oz. y 2 Castor oil fl.oz. 1 % Alcohol, to make • . . . . .fl.oz. 8 Dissolve the camphor in 4" fluidounces of alcohol, add the fluid extract, then the oils, and finally the remainder of the alcohol.— N. F. and U. S. P. 1890. This is practically identical with the preparation of the Brit. Pharm. 1885 (not in 1898 edition). Liniment of Oils. (Linimentum Olei.) Oil of cedar fl.oz. 1 Oil of cajeput fl.oz. 1 Oil of clove fl.oz. 1 Oil of sassafras fl.oz. 1 — Eclectic. Liniment of Oils, Compound. (Con- centrated Liniment.) Oil of origanum av.oz. 1 Oil of hemlock av.oz. 1 Oil of cajeput av.oz. 1 Camphor av.oz. 1 Capsicum, powder av.oz. l / 2 Mix, macerate for 14 days, agitating occasionally, and filter in a well-covered funnel. — Eclectic. Liniment of Opium. (Anodyne Lini- ment.) Tincture of opium fl.oz. 8 Soap liniment fl.oz. 8 —Brit. Pharm. Liniment of Opium, Ammoniated. Soap liniment • • fl.oz. 6 Compound camphor liniment, Brit. Pharm .fl.oz. 6 Tincture of opium fl.oz. 6 Belladonna liniment, Brit. Pharm fl.oz. 1 Stronger ammonia water. .. .fl.oz. 1 Mix, and after standing 7 days, filter quickly. — Brit. Form. Liniment of Opium, Compound. (Canada Liniment.) Tincture of opium. ...... .fl.oz. i l / 2 Camphor gr. 120 Alcohol fl.oz. 4 Oil of peppermint fl.dr. 3 Ammonia water, 10 p. c... fl.oz. 6 Oil of turpentine, to make. fl.oz. 16 Dissolve the camphor and the oil of peppermint in the alcohol, then add the tincture of opium, ammonia water .and enough oil of turpentine to make 16 fluidounces. Shake the mixture when- ever any of it is to be dispensed. This liniment will separate a short time after it has been mixed. It may be made somewhat more permanent by adding 3 fluidrams of tincture of soap bark to the ammonia water before add- ing it to the mixture. — N. F. Liniment of Petroleum, Compound. Crude petroleum •• fl.oz. 12 Ammonia water fl.oz. 2 Tincture of opium fl.oz. 2 Camphor gr. 120 Mix and dissolve. — Eclectic. Liniment of Potassium Iodid with Soap. Curd soap, recently prepared and in shavings av.oz. 2.Y\ Potassium iodid .-..av.oz. 2 Glycerin - fl.dr. 10 Oil of lemon m. 80 Distilled water fl.oz. 13) Reduce the soap to fine shreds, mix it with the water and glycerin in a porce- lain dish on a water bath ; when the soap is dissolved, oour the liquid into PHARMACEUTICAL PREPARATIONS. 229 a mortar in which the potassium has previously been powdered, mix briskly by trituration, continue the trituration until the mixture is cold, set aside for an hour, then incorporate the oil of lemon. — Brit. Pharm. Liniment, Rheumatic. Thomsonian (from the Materia Med- ica) : White soap • • lb. 3 Soft water pints 5 Capsicum, powder oz. 2 Oil of rosemary oz. 1 Oil of origanum • • oz. y 2 High wines gall. I Dissolve the soap in 4 pints of water by boiling, dissolve the camphor and oils in the high wines, and mix the two so- lutions. Mix the capsicum with one pint of boiling water, steep over a hot fire for 10 minutes, and pour this into the other mixture. Liniment, Soap. (Camphorated Tinc- ture of Soap, U. S. P. 1850.— Liquid Opodeldoc.) I. Castile soap, white, dried and granulated av.oz. 2 Camphor, small pieces av.oz. i l / 2 Oil of rosemary fl.dr. 2 l / 2 Alcohol • • fl.oz. 23 Water, to make fl.oz. s 2 Add the soap to 6 l / 2 nuidounces of boiling water and heat on a water bath until a clear gelatinous mass results. Mix this while yet warm with 16 fluid- ounces of alcohol and stir until solution is effected. Dissolve the camphor and oil in 7 nuidounces of alcohol by agita- tion. Add this solution to the warm soap mixture, mix thoroughly, and if necessary add water to make 32 fluid- ounces. Set aside in a cool place for 24 hours, and then filter. — U. S. P. It is customary to use about equal parts of white and mottled castile soaps. These may be granulated conveniently by grating, and then dried by exposing in thin layers to the air for several days. See also Spirit of Soap, Camphorated, which is a similar preparation. II. Soft (green) soap av.oz. 3 Camphor av.oz. 1 1 / 2 Oil of rosemary fl.dr. 4 Distilled water fl.oz. 6 Alcohol fl.oz. 23 Dissolve the soap in the water, the camphor and oil in the alcohol, mix the two solutions, set aside for one week, and filter. — Brit. Pharm. Liniment, Soap, Camphorated. (Opo- deldoc. — Solid Opodeldoc. — Sapo- nimentum Camphoratum.) I. Castile soap, white gr. 600 Camphor gr. 180 Oil of thyme m. 25 Oil ' of rosemary m. '45 Stronger water of ammo- nia ..- fl.dr. 6 l / 2 Alcohol fl.oz. 1 5 Introduce the soap, camphor, and al- cohol into a flask or suitable bottle, and apply a gentle heat until solution is ef- fected, taking care that no loss of alco- hol be incurred by evaporation. Filter the liquid, while hot, into another flask or bottle; warm again, if necessary, to render the contents liquid, add the oils and stronger water of ammonia, and when the whole has been thoroughly mixed, pour it into small dry vials, which should have been previously warmed, and should immediately be corked and cooled. — N. F. The quantity above given is usually divided into about 10 vials. Solid opo- deldoc is directed by the Germ. Pharm. to be prepared with soap made from animal fats ; but pure, white castile soap may be used, provided it has been pre- viously deprived of water. The stronger water of ammonia should be of the full strength prescribed^ by the U. S. P., viz., 28 per cent. II. Medicinal soap av.oz. 2 Camphor av.oz. l 2 Oil of thyme • • m. 50 Oil of rosemary m. 75 Ammonia water, 10 p. c. ... fl.dr. 10 Alcohol fl.oz. 24 The soap and camphor is to be dis- 230 STANDARD FORMULARY OF solved by the aid of a gentle heat in the alcohol, filtered in a covered funnel into a wide-mouthed bottle, to the filtrate add the oils mixed with the ammonia, close the bottle, and quickly cool the liquid. — Germ. Pharm. Liniment of Soap, Compound. Thomsonian (from the Materia Med- ica) : Camphor oz. I Soap oz. 3 Spirit of rosemary f int I Capsicum, powder oz. Yz Digest the soap and capsicum in the spirit until the soap is dissolved, and add the camphor. Liniment of Soft Soap. (Tincture of Green Soap, U. S. P. 1880.) I. Soft (i. e., green) soap av.oz. io^4 Oil of lavender flowers. .. .fl. dr. 2^ Alcohol, to make fl.oz. 16 Mix the oil with 5 fluidounces of al- cohol, dissolve in this the soap by agita- tion or stirring, set the solution aside for 24 hours, filter through paper, and then pass enough alcohol through the filter to make the filtrate measure 16 fluidounces. — U. S. P. The preparation of the U. S. P. 1890 contained seme water. See Spirit of Soap, which is similar. II. Smith's formula for making the preparation directly from oil and alkali : Linseed oil, raw av.oz. S J A Caustic potassa. • av.oz. 1% Oil of lavender flowers fl.dr. 2 l / 2 Alcohol fl.oz. 5 Water, to make fl.oz. 16 Dissolve the potassa in 3^2 fluidounces of water, put the solution into a bottle of the capacity of about 24 fluidounces, add the oil and alcohol, and shake the mixture briskly from time to time until there is no further separation of oil on standing. Let the solution stand in a moderately warm place for 24 hours, then dissolve in it the oil of lavender and add enough water to make 16 fluid- ounces. Purified cottonseed oil or olive oil may be substituted for the linseed oil, but the latter makes a brown prepara- tion of the color generally desired. The potassa should be of the U. S. P. strength, i. e., containing 90 per cent, of absolute potassium hydroxid. Liniment of Stillingia, Compound. (Stillingia Liniment.) I. Oil of stillingia... fl.oz. 1 Oil of cajeput .fl.dr. 4 Oil of lobelia 7. .fl.dr. 2 Alcohol fl.oz. 2 — Eclectic. This preparation is often used by Ec- lectics of weaker strength as follows : Oil of stillingia fl.dr. 4 Oil of caj eput fl.dr. 4 Oil of lobelia fl.dr. 1 Alcohol fl.oz. 3 In asthma and croup, the chest is to be bathed with this preparation and a few drops are to be taken on sugar. It is also used as an application for rheu- matism and sprains. II. This preparation has been improved by Eclectics as follows: Oil of stillingia..-. fl.oz. 1 Oil of lobelia fl.dr. 4 Oil of cajeput. fl.dr. 4 Alcohol fl.oz. 2 Glycerin fl.oz. 2 Mix ingredients in the order named. This preparation has the advantage over the original preparation, No. I, in that its component parts do not separate on standing. III. Oil of stillingia fl.dr. 9 Oil of cajeput fl.dr. 4 l / 2 Oil of lobelia .fl.dr. 2% Alcohol, to make fl.oz. 4 — Cine. Acad. Pharm. This is practically like No. I, but No. II should be preferred. Liniment, Stimulating. Thomsonian (from the Materia Med- ica) : White soap lb. 1 Whiskey (high proof) gall. 1 Capsicum, powder • . . .oz. 2 Water fl.oz. 8 Essence of hemlock. . .small amount PHARMACEUTICAL PREPARATIONS. 231 Melt the soap, add the whiskey, boil the capsicum with the water for 5 or 10 minutes, add the other liquid and a small amount of essence of hemlock. Liniment, Turpentine. (Kentish's Liniment or Ointment.) I. Resin cerate av.oz. 13 Oil of turpentine • . .fl.oz. 8 Melt the cerate in a capsule on a wa- ter bath, add the turpentine, and mix thoroughly.— U. S. P. The cerate should be melted at as low a temperature as possible and the oil added gradually until a smooth mixture results. This is a valuable application for burns and scalds, to be applied on lint soon after the occurrence of the acci- dent. Liniment of turpentine of the Brit, and Germ. Pharms. is a different prep- aration from the above, as may be ob- served. II. Soft (green) soap av.oz. 1% Camphor gr. 365 Oil of turpentine fl.oz. io}4 Distilled water, to make. . .fl.oz. 16 Mix the soap with 2 fluidounces of the water, dissolve the camphor in the oil, gradually add the latter solution to the former, triturating until the mix- ture becomes a creamy emulsion, and lastly add enough distilled water to make 16 fluidounces. — Brit. Pharm. III. Potassium carbonate parts 6 Soft (green) soap... parts 54 Oil of turpentine parts 40 Mix the potassium carbonate intimate- ly with the soap and add the oil.— Germ. Pharm. (2nd). Liniment, Turpentine, Acetic. (Com* pound Liniment of Turpentine — Linimentum Album — White Lini- ment — Stokes' Liniment — St. John Long's Liniment — White Oils.) I. Oil of turpentine fl.oz. 3 Fresh egg, albumen and yolk 1 Oil of lemon fl.dr. 1 Acetic acid, 36 per cent fl.dr. 5 Rose water fl.oz. 2 l / 2 Triturate or beat the contents of the egg with the two oils in a mortar until they are thoroughly mixed; then incor- porate the acid and rose water. Shake the mixture, whenever any of it is to be dispensed. — N. F. and Ec- lectic. See also Liniment of Turpentine and Acetic Acid, which contains some of the ingredients of the above. II. Redwood's formula for white oils: White and yolk of egg 1 Oil of turpentine fl.dr. 6 Solution of lead subacetate. fl.dr. 2 Alcohol fl.dr. 6 Diluted acetic acid ...fl.oz. 12 Triturate the egg and oil to a smooth mixture, add the solution, mix again, add the acid, mix once more, and finally add the alcohol. There are many other formulas extant for white oils. Liniment of Turpentine and Acetic Acid. (Camphorated Turpentine Liniment.) Oil of turpentine fl.oz. 4 Liniment of camphor fl.oz. 4 Acetic acid, glacial fl.oz. 1 —Brit. Pharm. See Liniment of Turpentine, Acetic, which contain some of the ingredients of the above. Liniment, Turpentine, Acid. (Bro- die's Liniment.) Sulfuric acid fl.dr. 1 Olive oil . . • • fl.oz.. 1 Oil of turpentine fl.oz. 1 Add the acid gradually to the olive oil, stirring in a mortar; when the mixture is cold, add the oil of turpentine. — New York Hospitals. Liniment of Turpentine, Compound. See Liniment, Turpentine, Acetic. Liniment, Verdigris. (Linimentum iEruginis — Mel or Unguentuni iEgyptiacum.) Verdigris av.oz. 1 Vinegar fl.oz. 7 Honey • • av.oz. 14 Dissolve the verdigris in the vinegar, •23-2 STANDARD FORMULARY OF strain, add the honey, and evaporate to proper consistence. This preparation is still occasionally demanded. The above are the directions of the former London Pharmacopeia. Lint, Medicated. (Turunda.) Lint may be medicated by saturating with a solution of the medicating sub- stance. The solvent is preferably water, though alcohol, ether or other liquids may be necessary. Sometimes mixtures of glycerin and other substances with water are advisable. Borated and car- bolated lint may be made, for example, by saturating a certain weight of ab- sorbent or purified lint with an aqueous solution, which may contain glycerin, containing the required amount of acid. The lint should be made to absorb all the liquid by kneading, as in making some of the gauzes (see Gauzes), then weighting down for several hours, and finally suspending on strings or wooden rods to dry. Iodoform lint may be prepared by dis- solving the requisite amount of iodo- form in ether or chloroform, saturating the lint with this liquid, weighting down for several hours, then suspending on strings or wooden rods to dry. Daylight must be excluded during the entire op- eration. The principal medicated lints in use and their strengths are as follows : Bo- rated, 10 per cent. ; carbolated, 5 p. c. ; and corrosive sublimate, 1 in 1000. Liquid, Blistering. (Liquor Epis- pasticus.) Cantharides, No. 20 powd..av.oz. S l /i Acetic ether, to make fl.oz. 16 Mix the drug with .4 fluidounces of acetic ether, pack in a percolator, at the end of 24 hours pour on acetic ether, allowing percolation slowly until 16 fluidounces of percolate are obtained. — Brit. Pharm. This preparation is twice the strength of that of the Brit. Pharm. 1885. Liquid Extracts. See Extracts, Liquid. Lotion, Alkaline. (Alkaline Wash.) Sodium carbonate gr. 60 Water fl.oz. 16 — Eclectic. Lotion of Ammonium Chlorid. Ammonium chlorid gr. 120 Water fl.oz. 1 Tincture of conium fl.oz. 1 Dissolve the salt in the water and add the tincture. — Eclectic. Another similar eclectic lotion is the following : Ammonium chlorid av.oz. 1 Water fl.oz. 8 Tincture of lobelia fl.oz. 4 Spirit of camphor .fl.oz. 4 Dissolve the salt in the water and add the tincture and spirit. Lotion, Astringent. (Warren's Styp- tic. — Styptic Balsam.) Sulfuric acid fl.oz. iJ4 Oil of turpentine fl.oz. 1 Alcohol fl.oz. 1 To the acid, contained in a wedgewood mortar, slowly add the oil, in small por- tions at a time, constantly stirring. Al- low the mixture to cool, then add the alcohol cautiously, in the same manner, and continue stirring until no more fumes arise. When the liquid is cold, pour it into a glass-stoppered bottle. In preparing this mixture, caution should be used, so that the temperature may not rise too high. Particular care is to be observed, if a larger quantity of this mixture is to be prepared. In this case it is preferable to prepare it in several portions. — N. F. The acid used for this preparation should be the so-called concentrated or 92^ per cent. acid. The above preparation was introduced many years ago by Dr. Jas. Warren, who used it internally for hemorrhages. Lotion, Black. (Black Wash. — Lotio Nigra. — Aqua Phagedoenica Nigra. — Lotio Hydrargyri Nigra. — Black Mercurial Lotion.) I. Calomel gr. 32 Water fl.dr. 2 Lime water, to make fl.oz. 8 Triturate the calomel with the water. PHARMACEUTICAL PREPARATIONS. 233 and gradually add a sufficient quantity of lime water to make 8 fluidounces. This mixture should be well agitated, whenever any of it is to be dispensed. — N. F. II. Calomel gr. 25 Glycerin m. 200 Mucilage of tragacanth. . . .fl.oz. 1 Lime water, to make fl.oz. 8 Triturate the calomel with the glyc- erin and mucilage, transfer to a bottle, add 2 fluidounces of lime water, agitate thoroughly, and then add the remainder of the water. — Brit. Pharm. Lotion of Borax. (Borax Lotion.— Cooling Wash.) Borax, powder gr. 240 Rose water fl.oz. 16 Mix and dissolve. — Eclectic. Some English preparations of the above title are also used ; these are as follows : I. Abercrombie's : Borax • . . . gr. 300 Diluted acetic acid fl.oz. 8 II. Copeland's : Borax gr. 80 Rose water fl.oz. 4 Orange flower water fl.oz. 4' III. Johnson's : Borax gr. 160 Chalk, precipitated av.oz. i}4 Rose water • • fl.oz. 4 Alcohol fl.oz. 4 IV. Meig's: Borax . av.oz. y 2 Morphine sulfate gr. 6 Rose water ...-..< fl.oz. 8 Lotion, Borax, with Morphine. Borax av.oz. 1 Morphine, sulfate gr. 12 Decoction of golden seal (strength not stated) fl.oz. 16 — Eclectic. This is used for inflamed eyes, mouth, fauces, nipples, etc. Lotion, Cooling. (Lotio Refrigerans. —Saline Wash.) Salt, table av.oz. y 2 Alcohol fl.oz. 4 Diluted acetic acid fl.oz. 4 Water fl.oz. 4 Mix, and dissolve the salt— Eclectic. Lotion, Ethereal, Compound. (Evap- orating Lotion.) Ether fl.oz. 3 Alcohol • fl.oz. 3 Solution of ammonium ace- tate fl.oz. 3 Rose water fl.oz. 7 — Eclectic. Lotion, Glycerin. Glycerin fl.dr. 4 Water fl.oz. 8 — Eclectic. Lotion of Golden Seal and Aconite. Golden seal, powder gr. 240 Water, boiling fl.oz. 4 Tincture of aconite fl.dr. 1 Make a decoction of the golden seal and water, filter, evaporate to 2 fluid- ounces, and add the tincture. — Eclectic. Lotion of Golden Seal, Compound. Strong infusion of green tea. fl.oz. 8 Strong infusion of golden seal fl.oz. 8 (strengths not specified.) Zinc sulfate • • gr. 60 Gunpowder gr. 60 Mix the decoctions, add the other in- gredients, agitate briskly, and after solu- tion has taken place and decomposition has ceased, decant the clear liquid from the sediment. — Eclectic. Lotion of Lead and Opium. (Lead and Opium Wash.) Lead acetate gr. 128 Tincture of opium fl.dr. 4 Water, to make fl.oz. 16 Dissolve the lead acetate in about 12 fluidounces of water, add the tincture, and enough water to make 16 fluid- ounces. This mixture should be well agitated, whenever any of it is to be dispensed. — N. F. Lotion, Lobelia, Compound. (Herpetic Wash.) Bayberry bark gr. 120 Lobelia herb gr. 120 Lobelia seed gr. 120 Yellow dock gr. 120 Vinegar or diluted acetic acid •• fl.oz. 16 Extract the mixed drugs by 7 days' maceraton or by percolaton. — Eclectic. •234 STANDARD FORMULARY OF The drugs may be extracted with di- luted alcohol. For erysipelas it is recommended to add 8 fluidounces of saturated solution of ammonium chlorid. This is used as an application in ery- sipelas and other skin diseases. Lotion, Mercurial, Cazenave's. Mercuric chlorid gr. 2 Spirit of camphor fl.dr. I Alcohol fl.oz. i% Distilled water, to make fl.oz. 8 — H. Lotion, Myrrh, Compound. Myrrh, powder gr. no Zinc acetate gr. 45 Lead acetate gr. IS Water fl.oz. 16 Boil the myrrh with a portion of the water for io or 15 minutes, when cold add the salts previously dissolved in the remainder of the water, let stand 24 hours, filter, and through the filter add enough water to make 16 fluidounces. This is used as an eye wash.— Eclectic. Lotion, Red. (Red Wash.) Zinc sulfate gr. 10 Compound tincture of laven- der •• .. .fl.dr. 2 Water, to make fl.oz. 4 Used as a urethral injection.— New York Hospitals. Lotion, Sassafras. Sassafras pith gr. 60 Rose water fl.oz. 16 Let stand for 4 hours, agitate occa- sionally, or boil for a few minutes, and strain. Distilled water may be substi- tuted for the rose water. — Eclectic. Lotion, Soda, Compound. Rock salt av.oz. 3 Zinc sulfate av.oz. 1 Iron persulfate (Monsel's salt) gr. 8 Soft water fl.oz. 16 — Eclectic. Lotion of Sulfur, Compound. (Tay- lor's Lotion.) Sulfur, sublimed gr. 90 Borax, powder av.oz. % Spirit of camphor .fl.dr. 1 Glycerin fl.dr. 1 V2 Water fl.oz. 3 Dissolve the borax in the water, add the spirit and then incorporate the mix- ture with the sulfur previously tritu- rated to a smooth paste with the glyc- erin. — New York Hospitals. Lotion, White. (White Wash.— Lo- tio Alba.) Zinc oxid gr. 120 Solution of lead subacetate.fl.dr. 3 Glycerin • • fl.dr. 4 Lead water, to make fl.oz. 4' —New York Hospitals. Another preparation of the same name used in hospitals and elsewhere is the following: Sulfurated potassa ("sulferet of potash") gr. 60 Zinc sulfate gr. 60 Water fl.oz. 4 Dissolve each in 2 fluidounces of wa- ter, and mix the solutions. Lotion, Yellow. (Yellow Wash. — Lo- tio Flava. — Aqua Phagedeenica ±iava. — Lotio Hydrargyri Flava. — Yellow Mercurial Lotion. — Altschaden Wasser.) Mercuric chlorid gr. 12 Water, boiling fl.dr. 2 Lime water, to make fl.oz. 8 Dissolve the chlorid in the boiling wa- ter, and add the solution to a sufficient quantity of lime water to make 8 fluid- ounces. This mixture should be well agitated whenever any of it is to be dispensed. — N. F. The preparation of the Brit. Pharm. is made from 17 grains of mercuric chlorid and 8 fluidounces of lime water. Lotion of Zinc, Compound. Zinc sulfate gr. 10 Alum • • gr. 10 Distilled water fl.oz. 16 — Eclectic. Lozenges. See Troches. Lubricant, Surgeon's. Fatty or oily substances, petrolatum, for example, have been used for lubri- cating surgical instruments, such as ure- thral sounds and vaginal specula. Lat- terly mucilaginous preparations are ad- vised for this purpose, as they may be PHARMACEUTICAL PREPARATIONS. 235 readily removed by washing with water. Such a preparation may be made as fol- lows : I. Tragacanth, whole gr. 48 Carbolic acid, linuefied m. 50 Glycerin fl.oz. 4 Distilled water fl.oz. 4 Mix the three liquids, pour upon tragacanth contained into a mortar or graduate, let stand for 12 to 24 hours or until the gum is thoroughly softened, then triturate or beat to a smooth paste. If desired still smoother, strain forcibly through cheese-cloth. Dispense in an ointment jar. II. A preparation now on the market is stated to contain the gelatin of Irish moss with oil of eucalyptus and for- maldehyde. Such a preparation may be made by adding to 16 fluidounces of mucilage of Irish moss, which see, 10 drops of oil of eucalyptus and 5 drops of formaldehyde solution. III. Dr. Gouley recommends this: White castile soap, powder. av.oz. 1 Water fl.oz. 3 Mucilage of Irish moss (1 av.oz. to 16 fl.oz.) fl.oz. 3 Formaldehyde solution (40 per cent.) m. 10 Thymol ..-• gr. 5 Oil of thyme, white.... m. 5 Alcohol . . . . .m. 15 Heat the soap and water, and stir un- til a homogeneous mixture is formed, add the mucilage, when cool add the formaldehyde, then the thymol and oil of thyme dissolved in the alcohol, stir, strain and keep in a covered vessel un- til all air-bubbles have vanished. The result is an opalescent substance of the consistence of honey, which should be put up at once in 2-ounce col- lapsible tubes and sterilized. IV. This is used by Leclerc and Guyon (Paris) : White castile soap, powder, glycerin, water, each, equal parts by weight. To 6 av.ounces of such add 30 grains of pure carbolic acid or betanophthol or 90 grains of resorcin. The last is pref- erable, as it is not caustic. Magnesium Tartrate. The Rademacher preparation is made (according to H.) by dissolving tartaric acid in twice its quantity of warm dis- tilled water, gradually adding magne- sium carbonate until neutralized, then evaporating the product on a water bath to dryness and rubbing to powder. Marrow. (Medulla.) Take fresh marrow from cattle, cut into small pieces and heat on a water bath until thoroughly melted, then strain with expression. The product may be dehydrated if desired by heating with a small amount of anhydrous sodium sulfate for about 15 minutes, stirring frequently, and fil- ter by hot filtration. Such a preparation will keep better than when not dehy- drated.— D. A factitious article may be prepared by melting 1 part of oil of theobroma and adding 2 parts of fresh lard. — H. Masses. These are soft solids intended to be divided into pills as required. They are made into mass form in the same man- ner as pills. The masses are called "pills" in the Brit. Pharm. Mass of Copaiba. (Solidified Copai- ba.— Pill of Capaiba, U. S. P. 1870.) Balsam of copaiba ...av.oz. 3 Magnesia, light, calcined gr. 84 Water sufficient Triturate the magnesia with a small amount of water, in a capsule, until the powder is uniformly dampened. Then gradually incorporate with it the copaiba so that a uniform mixture will result, place the capsule on a water bath, and heat during y 2 hour, frequently stirring. Lastly, transfer the mixture to a suit- able vessel and set this aside until the mass has acquired a pilular consistence. — N. F. Appendix and U. S. P. 1890. When balsam of copaiba is mixed with calcined magnesia, combination en- sues, a concrete mass being formed. Ail 236 STANDARD FORMULARY OF varieties of copaiba are not equally well adapted for making this preparation, de- pending on their relative contents of volatile oil and resin. The Maracaibo is the best, as it has the smallest pro- portion of oil. The presence of a small amount of water is also necessary to facilitate combination. This is the rea- son for moistening the magnesia before adding the copaiba. It is even advisable to agitate the latter with a small amount of water, allowing the water to subside, decanting the balsam, and mixing this with the magnesia as before. In the U. S. P. 1880 no heat was used, the mixture of balsam and magnesia be- ing allowed to stand until it became solid, usually about 8 or 10 hours. Mass of Iron Carbonate. (Vallet's Mass. — Vallet's Ferruginous Mass. — Pill of Carbonate of Iron, U. S. P. 1870.— Iron Pill or Pilu- la Ferri, Brit. Pharm.) I. Ferrous sulfate, pure, clear crystals av.oz. 4 Sodium carbonate, monohy- drated • gr. 805 Honey, clarified av.oz. i l / 2 Sugar, coarse powder av.oz. 1 Simple syrup, distilled wa- ter, each sufficient Dissolve the ferrous sulfate and the sodium carbonate, each separately, in 8 fiuidounces of boiling distilled water, and having added 6 fluidrams of simple syrup to the solution of the iron salt, filter both solutions, and allow them to become cold. Introduce the solution of sodium carbonate into a bottle or flask having a capacity of about 20 fiuidounces and gradually add the solution of the iron salt, rotating the vessel, constantly or frequently, until carbonic acid gas no longer escapes. Add enough distilled water to fill the bottle ; then cork it and set it aside that the ferrous carbonate may subside. When subsided pour off the supernatant liquid, and continue washing the precipitate by decantation with a mixture of 1 volume of simple syrup and 19 volumes of distilled water until the washings no longer have a saline taste. Drain the precipitate on a muslin strainer, and express as much water as possible. Then mix the pre- cipitate at once with the honey and sugar, and evaporate the mixture in a tared capsule on a water bath, with constant stirring, until it is reduced to a weight of 4 av. ounces. — U. S. P. This preparation contains approxi- mately 40 per cent, of ferrous carbonate. II. Pilula Ferri or Iron Pill: Ferrous sulfate, pure, dried.gr. 150 Sodium carbonate, pure, dried .gr. 95 Acacia, powder gr. 50 Tragacanth, powder gr. 15 Simple syrup fl.dr. 2 Glycerin • • m. 10 Distilled water m. 20 Mix the three liquids, add to the fer- rous sulfate contained in a mortar, mix well, add the sodium carbonate, mix by trituration, let stand for .15 minutes or until the reaction is complete, then add the gums, and mix thoroughly. If the mass is too hard, a small amount of water may be added. — Brit. Pharm. This contains 20 p. c. of ferrous car- bonate. III. Pilula Ferri Carbonici: Ferrous sulfate, pure, clear crystals av.oz. "j l / 2 Sodium bicarbonate, pure. av.oz. s l A Sugar, moderate fine powd...gr. 525 Honey, clarified av.oz. 334 Distilled water sufficient Dissolve the iron salt in 28 fluid- ounces of boiling distilled water and the sodium salt in 72 fiuidounces of luke- warm distilled water, and filter both so- lutions separately. Then mix the two filtrates thoroughly in a bottle (about i-gallon capacity'), fill the latter with hot distilled water, close the vessel, shake well, and set aside. When the precipitate has subsided, decant the clear liquid, refill the bottle with hot distilled water, shake well, and again set aside. Repeat this affusion of hot water and decantation of supernatant liquid until the wash-water gives but slight turbid- ity with solution of barium nitrate or PHARMACEUTICAL PREPARATIONS. 237 chlorid. Transfer the precipitate to a muslin strainer, allow the liquid to drain, mix it in a porcelain or enameled- iron capsule with the sugar and honey, and evaporate the mixture on a water bath to the weight of &% av. ounces. — Germ. Pharm. This mass is to be mixed with a suf- ficient quantity of althea and divided into pills, when the latter are required. See Pills of Iron Carbonate. Mass of Mercury. (Blue Mass. — Blue Pill. — Mercurial or Mercury Pill.) I. Mercury av.oz. 2 Licorice root, No. 60 powder.gr. 265 Althaea root, No. 60 powder.gr. 400 Glycerin gr. 240 Honey of rose av.oz. 2 Triturate the mercury with the glyc- erin and honey of rose until it is ex- tinguished, then gradually add the lic- orice and althaea and continue the trit- uration until the mass is homogeneous. — U. S. P. Keep in well-closed containers. This preparation is also to be had in the market in powder ' form known as "powdered blue mass." A preparation of this kind may be made according to the following formula: Mercury av.oz.. 1 Sugar, fine powder- av.oz. 1 Slippery elm bark, fine powd. av.oz. 1 Alcohol sufficient Triturate the mercury with the pow- dered bark, adding from time to time " enough alcohol to maintain a pasty con- sistence, till the mercury is extinguished. Then spread the mixture on paper to dry, then powder, 'and incorporate the sugar. II. Mercury av.oz. 2 Confection of rose av.oz. 3 Licorice root, fine powder. . .av.oz. 1 Triturate the mercury with the con- fection until the globules are no longer visible, and incorporate the licorice root. — Brit. Pharm. Medications, Homeopathic. Medications, in homeopathy, are of three kinds, powders, globules, and cones. The powders are prepared by adding to 10 gm. of milk sugar 1 cc. of the next lower than the desired strength of dilution (or 10 minims of dilution to 95 grains of milk sugar), mixing the same in a mortar with a spatula, then triturating with a pestle until fully dry. The resulting powder will represent the degree of strength next above the dilu- tion used in its preparation; that is, a 3x dilution will make a 4x powder, etc. As to the method of designating the strength of medications and other ho- meopathic preparations, see Dilutions, Homeopathic. Medicated globules, also called pellets or pilules, are made almost exclusively of cane sugar. They are formed into small globular masses of different sizes, designated according to the length of 10 globules laid in a straight row, meas- ured in millimeters. Globules are also made to a limited extent of milk sugar ; these will absorb alcoholic dilution con- taining a much larger percentage of water than will those made of cane sugar. Globules are medicated by placing them in a vial, adding the dilution in sufficient quantity, and allowing them to stand a sufficient length of time to become saturated ; any excess of liquid is then to be poured off. If necessary to remove the surplus fluid, the vial may be inverted on a clean, white blot- ting paper until the globules cease to cling together. In medicating cane-sugar globules, care should be exercised not to use a dilution having an alcoholic strength of much less than 88 per cent, or that of dispensing alcohol. As in the case of the powders, a dilu- tion of a certain strength will make globules of the next higher strength. Medicated cones, also called disks, are made of cane sugar, and rendered more absorbent by the addition of a small quantity of white of egg. which also I 238 STANDARD FORMULARY OF makes them very light and porous. They are formed into hemispherical masses, and are designated according to size by the diameter of the base in millimeters. The common size, numbered 6, should absorb about 2 drops of dispensing al- cohol. They are medicated exactly like the medicated globules described above. Mercury, with Chalk. (Gray Pow- der.) Mercury •• av.oz. 3 Honey, clarified gr. 350 Prepared chalk av.oz. _ AY* Water sufficient Weigh the mercury and honey into a strong bottle of the capacity of about 8 fluidounces and add 80 minims of wa- ter. Cork the bottle, and shake it for about V2. hour at a time, until the ag- gregate time of shaking reaches 10 hours or until the globules of mercury are no longer visible under a lens mag- nifying 4* diameters. This shaking may be more conveniently performed by me- chanical means. Rub the chalk with water in a mortar to a thick, creamy paste, and, having added the contents of the bottle, washing out the last portions with a little water, triturate the whole to a uniform mixture. Finally dry the mixture, first between ample layers of bibulous paper, and afterwards in a dish at the ordinary temperature until it weighs 8 av.ounces. Then reduce to uniform powder without trituration. Keep in well-stoppered bottles, pro- tected from light. — U. S. P. This preparation contains 38 per cent, of metallic mercury. The preparation of the Brit. Pharm. is made by triturating 1 av.ounce of mercury with 2 av.ounces of prepared chalk. Mercury with Magnesia. Triturate together 1 av.ounce of mer- cury with 2 av.ounces of magnesium car- bonate. Mercury, Soluble, Hahnemann's. The complex formula of Hahnemann is now replaced by the following from the British Homeopathic Pharmacopeia, which furnishes a satisfactory and uni- form preparation : Mercury (metal) gr. 132 Nitric acid, pure (68 p. c.) . .m. 80 Ammonia water .m. 70 Distilled water sufficient Mix the acid with 6Y 2 fluidrams of distilled water in a flask, and digest the mercury in the mixture, applying a grad- ually increased heat until about no grains of the metal have dissolved and a small portion of the solution diluted with about 20 times its bulk of distilled water yields a perfectly black precipi- tate with ammonia water. Dilute the hot solution with 10 fluidrams of dis- tilled water, and, while warm, filter it into a vessel containing 4 times its bulk of cold distilled water. Having thor- oughly mixed the filtrate with the wa- ter, add the ammonia water, previously diluted with 1 fluidounce of distilled wa- ter, in a thin stream, stirring constantly meanwhile. As soon as the precipitate has subsided, decant the supernatant liquid, shake the precipitate with a fresh portion of distilled water, collect it on a filter, wash it thoroughly, and dry it between folds of filtering paper, without the aid of heat. Milk of Magnesia. (Magnesia Mag- ma.) Magnesium carbonate av.oz. A l A Sodium hydrate av.oz. 2ft Water, to make n.oz. 61 Mix the magnesium carbonate with enough distilled water (about 17 fluid ounces) to make a smooth paste. Dis- solve the sodium hydrate in Uy 2 fluid ounces distilled water and add the solu- tion to the magnesia mixture with con- stant stirring and agitate frequently dur- ing 15 minutes. Wash the resuting magma by decantation, using about 4 pints of water each time, until the red color produced in Wx fluid ounces of the washings, by 3 drops of phenolphthalein T. S. is discharged by the addition of 1 drop of diluted sulphuric acid. Allow the precinitate to subside until it meas- PHARMACEUTICAL PREPARATIONS. 239 ures 2 fluid ounces. Decant the super- natant liquid.— U. S. P. One teaspoonful contains about 3 gr. of magnesium hydroxid. The water used in preparing this must be free from organic matter or the magma will become discolored. Mixture, ACE. (Chloroformum Mitigatum.) Alcohol volume i Chloroform volumes 2 Ether volumes 3 Mixture of Acacia. (Mixtura Gum- mosa.) Acacia, coarse powder gr. 85 Sugar gr. 85 Water fl.oz. 2 Dissolve the acacia and sugar in the water. This preparation should be freshly made, when wanted for use. — Germ. Pharm. (1st). Mixture of Ammonium Chlorid. (Mistura or Mixtura Solvens Simplex. — Mixtura Solvens. — Solvent Mixture. I. Ammonium chlorid gr. 180 Purified extract of licorice. . .gr. 180 Water, to make fl.oz. 16 Dissolve the solids in a sufficient quantity of water to make 16 fluid- ounces. — N. F. 6 fluidrams of glycerite of licorice may be advantageously substituted for the extract. II. Ammonium chlorid gr. 190 Purified extract of licorice. . .gr. 115 Water fl.oz. 16 — Germ. Form. Mixture of Ammonium Chlorid with Tartar Emetic. ( Mistura Solvens Stibiata.) Ammonium chlorid gr. 180 Purified extract of licorice, .gr. 180 Tartar emetic gr. 2 Water, to make fl.oz. 16 Dissolve the solids in the water. This may be prepared from the mix- ture of ammonium chlorid by adding to the latter the tartar emetic dissolved in a small quantity of water. Mixture, Antidiphtheritic, Warren's. Thymol gr. 6 Potassium chlorate gr. 55 Quinine sulfate gr. 32 Diluted hydrochloric acid.... m. 40 Glycerin fl.oz. 1 ^2 Brandy, to make fl.oz. 8 Mixture of Bismuth, Compound. Morphine hydrochlorid gr. 6 l / 2 Compound tincture of carda- mom fl.oz. 2^/2 Chloroform m. 56 Liquid extract of nux vom- ica, Brit. Pharm m. 108 Diluted hydrocyanic acid m. 256 Concentrated solution of bis- muth, Brit. Form fl.oz. 12 Distilled water, to make. . .fl.oz. 16 Dissolve the morphine in 3^2 fluidrams of water, and tincture, chloroform, ex- tract and acid, and finally the bismuth solution and the remainder of the wa- ter. — Brit. Form. Mixture of Bloodroot, Compound. (Cough Drops.) Syrup of ipecac, Syrup of squill, Syrup of tolu, Tincture of bloodroot, Paregoric, each equal parts — Eclectic. Mixture of Brandy. Brandy fl.oz. 4 Cinnamon water k . fl.oz. 4 Yolks of 2 eggs. Sugar av.oz. y 2 Triturate the yolk and sugar together, add the brandy and water, and mix well. — Brit. Pharm. This is a nutritive and stimulating preparation to be used in cases of pros- tration from fevers, etc. Mixture, Cajeput, Compound. (Hunn's Drops.) Oil of caj eput fl.oz. 1 ..fl.oz. 1 . .fl.oz. I . .fl.oz. I . .fl.oz. 4 Oil of clove. Oil of peppermint. Oil ot anise Alcohol This has been employed in the treat- ment of diarrhea, cholera, etc. — Eclec- tic. Mixture, Camphor, Acid or Hope's. (Antidysenteric Mixture — Mis- tura Antidysenterica.) Nitric acid m. 30 Tincture of opium m. 20 Camphor water, to make fl.oz. 4 240 STANDARD FORMULARY OF Mix the acid with about 2 fluidounces of camphor water, add the tincture, and lastly, enough camphor water to make 4 fluidounces. — N. F. The acid for the above should be the regular strength or 68 per cent. Hope's mixture originally contained nitrous acid instead of the nitric, as in the above. The fuming nitric acid which contains nitrogen tetroxid is the acid referred to as nitrous acid. Mixture, Camphor, Aromatic or Par- rish's. Comp. tinct. of lavender. .. .fl.oz. 1 Sugar gr. 60 Camphor water, to make. . . .fl.oz. 4 Mix the tincture with about 2 fluid- ounces of camphor water, dissolve the sugar in the mixture, and add enough camphor water to make 4 fluidounces. — N. F. Mixture of Camphor, Compound. Camphor water fl.oz. 5 Peppermint water fl.oz. 5 Spearmint water fl.oz. 5 Paregoric fl.dr. 10 — Eclectic. This is used for nausea and vomiting, the dose being one teaspoonful to one tablespoonful every 5 or 10 minutes. Mixture, Carminative. (Dalby's Car- minative.) Magnesium carbonate gr. 480 Potassium carbonate gr. 24 Tincture of opium fl.dr. 3 Oil of caraway drops 6 Oil of fennel drops 6 Oil of peppermint drops 6 Simple syrup fl.oz. 2>4 Water, to make fl.oz. 16 Triturate the oils with about 75 grains of magnesium carbonate, and 12 fluid- ounces of water gradually added. Then add the remainder of the magnesium carbonate and the other ingredients, and lastly add enough water to make 16 fluidounces. This preparation should be freshly made when wanted for use. Each fluidounce represents about 1 gr. of opium. — X. F. Mixture, Castor Oil. See Emulsion of Castor Oil, Xo. III. Mixture, Chalk. (Cretaceous Mix- ture.) Compound chalk powder. .. .gr. 365 Cinnamon water fl.dr. 13 Water, to make....„ fl.oz. 4' Rub the powder in a mortar with the cinnamon water and about 6 fluidrams of water, gradually added, to a uniform mixture; transfer to a graduate and rinse the mortar with enough water to make the product measure 4 fluidounces. — U. S. P. The U. S. P. does not direct the use of distilled water, but this is the only kind that should be used. This preparation should be freshly made, when wanted. The preparation of the Brit. Pharm. is made from 60 gr. of prepared chalk, 8 gr. of powdered tragacanth, 120 gr. of sugar, and cinnamon water to make 4 fluidounces. The tragacanth keeps the other solids in better suspension than the acacia of the U. S. P. prepara- tion. Mixture of Chloral and Potassium Bromid, Compound. (Chloral and Bromid Compound — Compound Elixir of Potassium Bromid — Compound Elixir of Chloral with. Potassium Bromid.) I. Chloral hydrate ...av.oz. 3. .gr. 130 Potassium bromid. .av.oz. 3. .gr. 130 Extract of cannabis indica, U. S. P gr. 15 Extract of henbane, U. S. P..gr. 15 Pumice, fine powder and well washed gr. 150 Water, to make fl.oz. 16 Triturate the extracts in a mortar with the pumice, gradually added, until they are thoroughly disintegrated. Dissolve the chloral hydrate and potassium bro- mid in 10 fluidounces of water, previous- ly heated to about 45 deg. C. and grad- ually add the hot solution to the ex- tracts and pumice with constant tritu- ration. Set the mixture aside during 24 hours, shaking it occasionally, and filter, adding enough water through the filter to make 16 fluidounces. One fluidram represents about 12 grains each of chloral hydrate and po- PHARMACEUTICAL PREPARATIONS. 241 tassium bromid and % gr. each of the extracts of cannabis indica and henbane. — N. F. Although this preparation is slightly weaker in chloral and bromid than the preparation heretofore recommended in the N. F., it possesses the advantage of holding the active constituents of the extracts completely in solution and is believed to be in other respects more satisfactory. III. The Brit. Form, recognizes a similar preparation under the name "compound solution of bromo-chloral'.' : Potassium bromid gr. 1280 Chloral hydrate gr. 1280 Juice of henbane gr. 1280 Tincture of cannabis indica, Brit. Pharm m. 320 Tincture of fresh orange peel m. 320 Simple syrup fl.oz. 3 Liquid extract of licorice. . .m. 190 Distilled water, to make, .fl.oz. 16 Dissolve the potassium bromid in 5 J / 2 fluidounces of the water, dissolve the syrup and extract, add the bromid solu- tion to the chloral solution, filter, and wash the filter with just enough distilled water to make the filtrate measure 16 fluidounces. This should be shaken when it is to be dispensed. Each fluidram contains 10 gr. each of chloral hydrate and potassium bromid. Mixture of Chloroform and Canna- bis Indica, Compound. (Chloro- form Anodyne — Chlorodyne — Mixture of Chloroform and Opium — Tincture of Chloroform and Morphine.) Chloroform fl.oz. 2 Tincture of Indian cannabis. fl.oz. 3 Tincture of capsicum fl.dr. 4 Stronger ether fl.dr. 4 Morphine sulfate gr. 18 Oil of peppermint m. 15 Glycerin .'.fl.oz. 2 Water , fl.oz. 1 Alcohol, to make fl.oz. 16 Dissolve the oil in 8 fluidounces of al- cohol, add the chloroform, ether, and the tinctures. Mix well, and add the morphine sulfate, previously dissolved in the water and glycerin, and then add the remainder of the alcohol. — N. F. Each fluidram represents about 7 min- ims of chloroform, n minims of tinc- ture of Indian cannabis, 2 minims oi tincture of capsicum, and 1/7 gr. of morphine sulfate. See under heading Chlorodyne. Mixtures, Cholera or Diarrhea. I. Bevan's : There are two preparations of this, one being a preventive or prophylactic, which is as follows : Magnesium sulfite gr. 120 Sulfurous acid fl.oz. 2 Distilled water fl.oz. 2 Tincture of capsicum fl.dr. 4 Dissolve the sulfite in the water, and add the other ingredients. This is used when there is suspicion of possible disease, the dose" being a teaspoonful night and morning. The other preparation, called the ther- apeutic or the remedy, differs from the above only in the addition of 2 grains of morphine sulfate. This is used when disease is actually present, the dose being a teaspoonful every half hour until relieved. II. Casey's : Potassium bicarbonate gr. 120 Comp. spirit of lavender. . .fl.dr. 2 Spirit of camphor fl.dr. 4 Spirit of ammonia fl.oz. 1 Spirit of peppermint fl.oz. 1 Comp. spirit of ether fl.oz. 1 Tincture of opium fl.oz. 1 III. Christensen's : Chlorodyne fl.dr. 4 Paregoric fl.oz. 1 Tincture of opium fl.dr. 2 Tincture of catechu fl.oz. 1 Neutralizing cordial fl.dr. 10 IV. Close's (Geo. C.) : Diluted sulfuric acid fl.oz. 1 Comp. tincture of cardamom. fl.oz. 2 Sugar av.oz. 4 Spearmint water fl.oz. 9 Take 2 teaspoonfuls in a wineglassful of water, after each evacuation; as a tonic, take one teaspoonful 3 times a day. The mixture is useful in chronic diarrhea. 24: STANDARD FORMULARY OF V. Dunlap's : Tincture of ginger fl.oz. 3 Spirit of peppermint fl.oz. 3 Tincture of opium fl.dr. 4 Tincture of capsicum fl.dr. 2 Spirit of camphor fl.dr. 4 Hoffmann's anodyne fl.dr. 4 A teaspoonful to be taken after each stool. VI. Ebert's: Solution of iron nitrate fl.dr. 2 Deodorized tinct. of opium.. fl.dr. 2 Caraway water fl.dr. 4 Dose, from H to 1 teaspoonful after each evacuation. VII. Greenhow's: Guaiac resin av.oz. ]/z Clove, powder av.oz. x / 2 Cinnamon, powder av.oz. y 2 Brandy fl.oz. 16 Macerate the drugs in moderately fine powder with the brandy for 14' days, and filter. The dose is from a teaspoonful to a tablespo mful, in sweetened water, every 15 or 20 minutes until relief is ob- tained. VIII. Hamlin's (1) : Tincture of opium fl.oz. 1 Tincture of rhubarb fl.oz. 1 Spirit of camphor fl.oz. 1 IX. Hamlin's (2) : Tincture of opium fl.oz. 1 Tincture of ginger fl.oz. 1 Tincture of capsicum fl.dr. 4 Tincture of cardamom fl.oz. 1 This is used in the second stage of cholera when there is threatened col- lapse. X. Harney's (Gen'l) : Chloroform fl.oz. 1 Tincture of opium fl.oz. 1 Spirit of cinnamon fl.oz. 1 Spirit of peppermint fl.oz. 2 Camphor, powder gr. 16 Syrup of ginger fl.oz. 2 Mix and dissolve. XI. Loomis : Tincture of opium fl.dr. 4 Tincture of rhubarb. ...... .fl.dr. 2 Comp. tincture of gambir. . .fl.oz. 1^2 Oil of sassafras m. 20 Compound tincture of laven- der, to make fl.oz. 4 XII. Rubini's: Camphor av.oz. 1 Hoffmann's anodyne fl.oz. 2 Dose : 2 to 5 drops on sugar every 20 minutes until relieved. XIII. Rademacher's (in H.) : Zinc acetate gr. 90 Distilled water fl.oz. 6 Mucilage of acacia fl.oz. 1 XIV. Ruschenberger's : Tincture of opium fl.oz. 1 Spirit of camphor fl.oz. 1 Tincture of capsicum fl.oz. 1 Spirit of peppermint fl.oz. 1 Aromatic tincture of rhubarb, fl.oz. 1 Dose: 30 to 40 drops in water. XV. Russian : Thielmann's may be dispensed, though other similar mixtures are used. XVI. Scammon's : Tincture of opium fl.dr. 3 Spirit of camphor fl.dr. 3 Tincture of capsicum fl.dr. 1 Diluted alcohol fl.dr. 1 XVII. Squibb's (in N. R— also called compound tincture of opium) : Tincture of opium fl.dr. 6 Tincture of capsicum fl.dr. 3 Spirit of camphor fl.dr. 6 Chloroform fl.dr. 2^2 Alcohol fl.dr. 14 XVIII. Sun : Tincture of opium fl.dr. 6 Tincture of capsicum .fl.dr. 3 Tincture of rhubarb fl.dr. 3 Spirit of camphor fl.dr. 6 Spirit of peppermint fl.dr. 6 Alcohol fl.dr. 6 Mix them and filter. XIX. Swedish : Thielemann's are also known by this name. XX. Thielemann's : Wine of opium fl.oz. 1 Tincture of valerian fl.oz. 1^2 Ether, stronger fl.dr. 4 Oil of peppermint fl.dr. 1 Fluid extract of ipecac m. 16 Alcohol to make fl.oz. 4 This preparation is practically identi- cal with the Mistura Thielemanni of the Swedish Pharmacopeia. Thielemann's Mixture of the Swedish PHARMACEUTICAL PREPARATIONS. 243 Pharm. is made from 2 parts of oil of peppermint, 22 of alcohol, 10 of wine of opium with saffron (containing 10 p. c. of opium and 3 1/3 p. c. of saffron), 25 of wine of ipecac (1:10), and 40 of ethereal tincture of valerian (1:5). XXL Velpeau's: Tincture of opium fl.dr. 10 Compound tincture of gam- bir fl.dr. 21 Gum camphor gr. 65 Mixture, Cochineal. Cochineal, powder gr. 10 Potassium carbonate gr. 20 Water fl.oz. 4 Sugar to sweeten — Eclectic. Mixture, Copaiba, Compound. The first two preparations given below are mentioned by the N. F. ; the third is an Eclectic preparation. I. Lafayette Mixture : Balsam of copaiba fl.oz. 2 Spirit of nitrous ether fl.oz. 2 Compound tincture of lav- ender fl.oz. 2 Solution of potassa fl.dr. 4 Simple syrup fl.oz. 5 Mucilage of acacia. to make fl.oz. 16 Mix the balsam with the solution and the spirit. Then add the tincture, and lastly, the syrup and mucilage. Mix the whole thoroughly by shaking. This mixture should be well agitated, whenever any of it is to be dispensed. Each fluidram contains 7H minims of copaiba. In the former N. F., this was made with mucilage of dextrin and the mix- ture was said not to separate so quickly. A mixture of somewhat similar com- position, in considerable use in some parts of the country, is the following : IL Chapman's Mixture: Balsam of copaiba fl.oz. 4 Spirit of nitrous ether fl.oz. 4 Compound tincture of lav- ender fl.oz. 1 Tincture of opium fl.dr. 4 Mucilage of acacia fl.oz.. 2 Water to make fl.oz. 16 III. Eclectic (also called Diuretic Drops) : 16 Spirit of nitrous ether fl.oz. 2 Sweet almond oil fl.oz. 2 Balsam of copaiba fl.oz. 1 Oil of turpentine fl.oz. 1 Camphor gr. 20 Mixture, Copper. Rademaqher's : Tincture of copper acetate, Rademacher's m. 60 Mucilage of acacia fl.dr. 5 Cinnamon water fl.oz. 2>Va Distilled water fl.oz. zVa — H. Mixture, Creosote. Creosate, beechwood m. 4 Spirit of juniper m. 4 Simple syrup fl.dr. 2 Distilled water, to make fl.oz. 4 —Brit. Pharm. The preparation of 1885 had also 4 m. of glacial acetic acid (equal to about 1 fluidram of diluted acetic acid). Mixture, Eucalyptus, Compound. This preparation is used in this city for gonorrhea: Mucilage of acacia fl.oz. 2 Solution of potassa » fl.oz. V/z Sandalwood oil fl.oz. 2 Fluid extract of eucalyptus. fl.oz. 1 Fluid extract of cubeb fl.oz. 2 Camphor water fl.oz. 4 Water, to make fl.oz. 16 Mixture, Expectorant, Stokes'. (Stokes' Expectorant.) Ammonium carbonate gr. 128 Fluid extract of senega. . . .fl.dr. 4 Fluid extract of squill fl.dr. 4' Camphorated tincture of opium fl.oz. 2 l / 2 Ammonia water sufficient Water fl.oz. i]/ 2 Syrup of tolu, to make. .. .fl.oz. 16 Neutralize the fluid extract with ex- actly sufficient ammonia water. To this add the fluid extract, the tincture and the ammonium carbonate, previously dissolved in the water, and then add the syrup of tolu. — N. F. Mixture, Gentian, Alkaline. This preparation is used in some Eng- lish hospitals. Its formula is : Sodium bicarbonate gr. 240 Diluted hydrocyanic acid....m. 50 Compound infusion of gen- tian fl.oz. 16 244 STANDARD FORMULARY OF Mixture of Guaiac. (Guaiacum Mix- ture.) Guaiac resin, powder gr. 180 Sugar gr. 180 Acacia, fine powder gr. no Cinnamon water fl.oz. 16 Triturate the powdered guaiac with the sugar and acacia, then gradually add the cinnamon water, and mix thor- oughly. This mixture should be well agitated, whenever any of it is to be dispensed. — N. F. The preparation of the Brit. Pharm. differs from the above only in containing 27 gr. of powdered tragacanth for the acacia. Mixture, Iron. Rademacher's : Tincture of iron acetate, Rademacher's fl.oz. 1 Mucilage of acacia fl.oz. \ Y / 2 Water fl.oz. s J A — H. Mixture of Iron, Acid. A preparation similar to this is used in hospitals : Ferrous sulfate gr. 80 Magnesium sulfate gr. 360 Diluted sulfuric acid fl.dr. 1 Infusion of quassia, to make fl.oz. 4 Mixture of Iron, Aromatic. (Heber- den's Mixture or Ink.) This English preparation is some- times used here : Pale cinchona av.oz. ^ Columbo gr. 150 Clove gr. 100 Iron filings gr. 180 Compound tincture of car- damom fl.oz. 2]/ 2 Tincture of orange peel. . .fl.dr. 2 l / 2 Peppermint water, to make. fl.oz. 16 Reduce the cinchona, columbo and clove to coarse powder, digest with 12 fluidounces of peppermint water, in a closed vessel for 3 days, agitating fre- quently, strain, and add the other in- gredients. Mixture, Iron, Compound. (Griffith's Mixture. — Griffith's Myrrh Mix- ture. — Antihectic Mixture. — Mis- tura Ferri Composita. — Ferrated Emulsion of Myrrh.) Ferrous sulfate, pure, clear crystals gr. 45 Potassium carbonate gr. 60 Myrrh, pieces gr. 135 Sugar gr. 135 Spirit of lavender fl.oz. 1 Rose water, to make fl.oz. 16 Break the myrrh into small pieces, mix it and the sugar and potassium carbonate, in a mortar, with 12 fluid- ounces of rose water, at first gradually added, so that a uniform mixture may result. Transfer this to a graduate, add the spirit, and then the ferrous sul- fate, previously dissolved in about 1 fluidounce of rose water, and lastly enough rose water to make the product measure 16 fluid ounces. — N. F. The myrrh used for this preparation should be selected pieces of the gum ; on no account should the powder be employed. The N. F. directs the preparation to be freshly made, when wanted. How- ever the above mixture may be made up without the iron, to 15 fluidounces, to the latter adding the ferrous sulfate dissolved in 1 fluidounce of rose water when the mixture is wanted. The mix- ture without the iron is quite stable. The Brit. Pharm. uses 42 gr. of fer- rous sulfate, 50 of potassium carbonate, 100 each of myrrh and sugar, 85 minims of spirit of nutmeg and rose water to make 16 fluidounces. Mixture of Licorice, Compound. (Brown Mixture. — Mistura Fus- cus.) I. Pure extract of licorice. . .av.oz, y 2 Acacia, granulated av.oz. J / 2 Spirit of nitrous ether fl.dr. 4 Simple syrup fl.dr. 6y 2 Wine of antimony fl.oz. 1 Paregoric fl.oz. 2 Water, to make fl.oz. 16 Rub the extract and acacia in a mor- tar with 8 fluidounces of water until they are dissolved. Transfer this solu- tion to a graduate containing the other ingredients, and rinse the mortar with PHARMACEUTICAL PREPARATIONS. 245 enough water to make the product measure 16 fluidounces. — U. S. P. If glycerite of licorice be used instead of the extract, a preparation will be ob- tained which is almost free from insolu- ble matter. II. Extract of licorice, powder, .gr. 120 Acacia, powder gr. 120 Sugar gr. 120 Paregoric fl.oz. 1 Tincture of bloodroot fl.dr. 4 Spirit of nitrous ether fl.dr. 2 Water fl.oz. 6 Triturate the three solids with the water until practically dissolved, strain, and add the other ingredients. — Eclectic. Mixture of Linseed Oil. The following have been used under this name : I. Linseed oil, raw fl.oz. 3 Yolk of egg fl.oz. 4 Cinnamon water, to make.. fl.oz. 16 Make an emulsion. II. Linseed oil, raw fl.oz. 4 Lemon j uice fl.oz. 2 Mucilage (any kind, acacia, dextrin, etc.) fl.oz. 1 Water, to make fl.oz. 12 Mixture of Magnesia and Asafetida. (Dewees' Carminative.) Magnesium carbonate gr. 360 Tincture of asafetida fl.dr. g l / 2 Tincture of opium m. 80 Sugar av.oz. 1^4 Distilled water... to make fl.oz. 16 Rub the magnesium carbonate and sugar in a mortar, with the two tinc- tures, then gradually add enough dis- tilled water to make the mixture meas- ure 16 fluidounces. — N. F. and U. S. P. 1880. Mixture of Oils, Camphorated. (Mis- tura Oleorum Camphorata.) Oil of clove fl.oz. 1 Oil of cajeput fl.oz. 1 Oil of amber, rectified fl.oz. 1 Camphor av.oz. 1 — Eclectic. I his is used to relieve toothache. This preparation has been sold exten- sively under the name of "Parisen's Vegetable Specific." Mixture of Oils, Compound. (Verm- ifuge Oil.) Castor oil fl.oz. 2 Oil of wormseed fl.oz. 2 Oil of turpentine fl.oz. 1 Oil of anise fl.oz. 1 — Eclectic. Use in teaspoonful doses for adults, every 2 hours. After using for 2 or 3 days, a purgative should be taken. Mixture, Oleo-Balsamic. (Mixtura Oleoso-Balsamica. — Balsamum Vitee Hoffmanni. — Hoffmann's Balsam of Life.) Oil of lavender flowers m. 30 Oil of thyme m. 30 Oil of lemon m. 30 Oil of nutmeg m. 30 Oil of orange flowers m. 30 Oil of clove m. 25 Oil of cinnamon m. 25 Peru balsam m. 80 Alcohol, to make fl.oz. 16 Dissolve the oils and the balsam in the alcohol, let the solution stand a few days, and then filter. — N. F. The formula of the Germ. Pharm. is practically the same as the above, but contains no oil of orange flowers, al- though the earlier editions of this work did specify this ingredient, also men- tions eugenol instead of oil of clove. The preparation of the Austr. Pharm. contains no oil of thyme. Mixture of Rhubarb, Compound. (Squibb's Rhubarb Mixture.) Fluid extract of rhubarb. .. .m. 90 Fluid extract of ipecac m. 15 Sodium bicarbonate gr. 175 Glycerin fl.oz. 4 Peppermint water, to make fl.oz. 16 Dissolve the sodium bicarbonate in about 8 fluidounces of peppermint water, then add the fluid extracts and glycerin, and lastly, enough peppermint water to make 16 fluidounces. — N. F. This is closely related to mixture of rhubarb and soda, U. S. P., containing the same ingredients as the latter, but the official mixture is about 20 per cent, the stronger. 246 STANDARD FORMULARY OF Mixture of Rhubarb and Soda. Sodium bicarbonate gr. 256 Fluid extract of rhubarb. . .fl.dr. 2 Fluid extract of ipecac m. 25 Spirit of peppermint fl.dr. 4^4 Glycerin fl.oz. 5 l A Water, to make fl.oz. 16 Dissolve the sodium bicarbonate in about 7 fluidounces of water, then add the fluid extracts, the glycerin, and the spirit, and the remainder of the water. — N. F. Mixture of Sassafras and Opium. (Mistura Opii Alkalina. — God- frey's Cordial.) Oil of sassafras m. 8 (about drops 12) Tincture of opium fl.dr. 4 Alcohol fl.dr. 6 Potassium carbonate gr. 60 Molasses fl.oz. 5 Water, to make fl.oz. 16 Mix the tincture with the alcohol in which the oil had previously been dis- solved. Dissolve the potassium carbon- ate in about 8 fluidounces of water, mix this with the molasses, then add the mixture first prepared, and lastly, enough water to make 16 fluidounces. Allow the mixture to become clear by standing, then pour off the liquid por- tion and preserve it for use. Each fluidram contains 2 minims of tincture of opium, corresponding to about 1/5 gr. of opium. — N. F. Mixture of Soda. Fluid extract of rhubarb fl.dr. 2 Tincture of cinnamon fl.dr. 4 Brandy fl.dr. 2 Sodium bicarbonate gr. 60 Oil of clove f drops 2 Simple syrup fl.oz. 3 Water fl.oz. 4 This is similar to Mixture of Rhubarb and Soda and Mixture of Rhubarb, Compound, which see. Mixture of Soda and Spearmint. (Soda Mint.) Sodium bicarbonate gr. 360 Aromatic spirit of ammonia. m. 75 Spearmint water, to make. fl.oz. 16 Dissolve the sodium bicarbonate in about 12 fluidounces of spearmint water, add the spirit and enough spearmint water to make 16 fluidounces. Filter, if necessary. — N. F. While the above directs the use of spearmint water, peppermint water is generally employed. Mixture, Splenetic. (Spleen Mixture. — Gadberry's Mixture.) Ferrous sulfate, pure gr. 100 Quinine sulfate gr. 100 Nitric acid m. 100 Potassium nitrate gr. 300 Water, to make fl.oz. 16 Triturate the ferrous sulfate, reduced to powder, with the acid previously mixed with an equal volume of water. When effervescence has ceased, warm the mixture gently, until it no longer evolves visible vapors of a yellowish tint. Then add to it the quinine sulfate, the potassium nitrate, and lastly, enough water to make 16 fluidounces. When solution has been effected, filter. Mixture, Startin's. Magnesium sulfate gr. 360 Ferrous sulfate gr. 60 Diluted sulfuric acid fl.dr. 2 Syrup of wild cherry fl.oz. 1 Water, to make fl.oz. 4 This is given in teaspoonful doses to be taken after meals. Another mixture used by Dr. Startin is the so-called "acid aperient mixture," which is prepared as follows : Magnesium sulfate av.oz. 3 Diluted sulfuric acid fl.dr. 3 Fluid extract of licorice. .. .fl.dr. 3 Water, to make fl.oz. 16 The first mentioned, the tonic mixture, is the one generallv used in this coun- try. It is frequently made with some syrup other than syrup of wild cherry, such as simple syrup. The "mixture of iron, acid," is a slight variation of this mixture. Mixture, Sulfuric Acid. (Haller's Acid Elixir.) Sulfuric acid av.oz. 1 Alcohol av.oz. 3 Add the acid very gradually to 3 av. ounces of alcohcl, contained in a flask, agitating after each addition, and taking care that the temperature of the mix- ture be not allowed to rise above 50 PHARMACEUTICAL PREPARATIONS. 247 deg. C. When the mixture is cold, add enough alcohol, if necessary, to make 4 aw ounces. The same product may be obtained, approximately, by carefully and slowly adding I volume of sulfuric acid to 7 volumes of alcohol, and this method may be used when small quantities are required for immediate use in a pre- scription. — N. F. and Germ. Pharm. The sulfuric acid used in this prep- aration should be chemically pure and of the strength designated by the U. S. P., viz., g2]/ 2 per cent, of absolute acid. Mixture of Tar Oil. (Tar Mixture.— Mistura Picis Liquidae.) Purified extract of licorice, .gr. 480 Oil of tar, pure fl.dr. 4 Chloroform m. 75 Oil of peppermint m. 20 Alcohol fl.oz. 2]/ 2 Sugar av.oz. 4^1 Water, to make fl.oz. 16 Add the extract and sugar to 10 fluid- ounces of water, contained in a covered vessel, and heat the mixture to boiling until the solids are dissolved. Then add the oil of tar, cover the vessel, and allow the contents to cool, stirring occa- sionally. Next add the chloroform and oil of pepperment previously dissolved in the alcohol, and lastly, enough water to make 16 fluidounces. This mixture should be well agitated, when any of it is to be dispensed. — N. F. Mixture, Taraxacum Laxative. The following is used in this city un- der the above name : Magnesium sulfate av.oz. 1 Diluted nitromuriatic acid, .fl.oz. 1 Fluid extract of conium. .. .fl.oz. 1 Fluid extract of dandelion, .fl.oz. 4 Aromatic fl. ext. of cascara. fl.oz. 4 Water, to make fl.oz. 16 Mixture, Tonic, Compound. (Mistura Alterantise Composita.) Ferrous sulfate gr. 40 Sodium phosphate gr. 240 Quinine (alkaloid) gr. 128 Strychnine (alkaloid) gr. 4 Sugar av.oz. g% Diluted phosphoric acid. . .fl.oz. g l / 2 Distilled water sufficient Dissolve the iron sulfate in 6 fluidrams of boiling distilled water, also dissolve the sodium phosphate in i l / 2 fluidounces of boiling distilled water, and mix the 2 solutions ; collect the precipitate and wash it with distilled water until the washings are tasteless; add this preci- pitate together with the quinine and strychnine to the diluted phosphoric acid, shake until dissolved, add the sugar, dissolve without heat and strain. — Ec- lectic. This is similar to Easton's Syrup. Mixture, Wormseed, Compound. (Mistura Chenopodii Composita — Worm Mixture.) Castor oil fl.oz. 3 Oil of wormseed fl.dr. 3 Oil of anise fl.dr. 3 Tincture of myrrh fl.dr. 3 This is a vermifuge, to be used in doses of one teaspoonful for an adult 3 or 4 times daily for 3 successive days, then to be followed by a cathartic. — Ec- lectic. Mixture, Zollickoffer's. Potassium iodid gr. 20 Guaiac resin gr. 20 Wine of colchicum root fl.dr. 1 Cinnamon water fl.oz. 2 Syrup of ginger fl.oz. 2 Sometimes simple syrup is used in- stead of syrup of ginger. Mollin. See Soap, Fat. Mucilage of Acacia. (Mucilage of Gum Arabic. ) Acacia, in small fragments. av.oz. 6J4 Lime water av.oz. 6 l A Distilled water 7 sufficient Wash the acacia with cold water and allow it to drain. Add the lime water and enough water to make the mixture weigh i&/ 2 av. ounces, agitate or stir occasionally until the gum is dissolved, and strain. — U. S. P. The product measures about 16 fluid- ounces. It should be kept in well-stop- pered, completely filled bottles, in a cool place. Only the best select acacia in clean. clear ' tears (never in powder) should 248 STANDARD FORMULARY OF be used. The water should be cold or at most lukewarm, not hot. The lime water facilitates solution and aids in preserving the preparation. Tolu water is another excellent solvent and preservative for use in this prepapa- tion and has been highly recommended for this purpose. The preparation of the Brit. Pharm. is made from 6% av. ounces of gum and 9 fluidounces of distilled water; dissolve in a closed vessel and strain. The preparation of the Germ. Pharm. is made from I av. ounces of gum and 2 av. ounces of distilled water. Mucilage of Dextrin. Dextrin av.oz. 5^4 Water, to make fl.oz. 16 Mix them in a tared vessel, and heat the mixture, under constant stirring, to near boiling, until the dextrin is dis- solved and a limpid liquid results. Then restore any loss of water by evaporation, strain the liquid through muslin, and allow it to cool short of gelatinizing, when it will be ready for immediate use. If the mucilage is not at once to be used for preparing emulsions or other mixtures, transfer it, while hot, to bot- tles, which should be filled to the neck. Then pour into each bottle a sufficient quantity of olive or other bland fixed oil to form a protecting layer, and when the mucilage has gelatinized, securely cork the bottles, and keep them in a cool place, in an upright position. When gelatinized mucilage of dextrin is to be used for the preparation of emulsions or for other mixtures, pour off the protecting layer of oil from the surface, remove the remainder of the oil by a pellet of absorbent cotton and warm the bottle gently, until the muci- lage is liquefied. Then allow it to cool short of gelatinizing. The kind of dextrin suitable for this preparation is the commercial, while variety, provided it still contains some unaltered or only partially altered starch and forms a jelly on cooling when made into a mucilage after the formula above given. The yellow variety, which is completely soluble in 2 parts of cold water, will not answer the purpose. Mucilage of Elm. (Mucilage of Slip- pery Elm Bark. — Mucilago TJlm- us.) Slippery elm bark, bruised. av.oz. I Water fl.oz. 16 Digest the bark with the water on a water bath during i hour, then strain. Elm bark is difficult to bruise so that it is advisable to grind it coarsely in a mill or to cut it with an herb cutter. This preparation should be freshly made when wanted. Mucilage of Irish Moss. (Mucilage of Chondrus or Carrageen.) Irish moss av.oz. y 2 Water, to make fl.oz. 16 Wash the Irish moss with cold water, then place it in a suitable vessel, add 16 fluidounces of water, and heat it, on a boiling water bath, for 15 minutes, frequently stirring. Then strain it through muslin, and pass enough water through the strainer to make the liquid, when cold, measure 16 fluidounces. This preparation may also be made in the following manner : Gelatin of Irish moss gr. 145 Water, to make fl.oz. 16 Heat the gelatin with 16 fluidounces of water, at a boiling temperature, until it is completely dissolved. Then allow the solution to cool, and add enough water, if necessary, to make 16 fluid- ounces. Mucilage of Irish moss, thus prepared, is well adapted for the preparation of emulsions of fixed oils. If it is, how- ever, required for admixture with clear ' liquids, it should be diluted, when fresh- ly made, and while still hot, with about 3 volumes of boiling water, filtered, and the filtrate evaporated to the volume corresponding to the proportions above given. The filtration may be greatly facilitated by filling the filter loosely PHARMACEUTICAL PREPARATIONS. 249 with absorbent cotton, and pouring the liquid upon the latter. This mucilage may be preserved for some time by transferring it, while hot, into bottles, which should be filled to the neck, then pouring a layer of olive or other bland fixed oil on top, securely stoppering the bottles, and keeping them in an upright position in a cool place. When the mucilage is wanted for use, the layer of oil may be removed by means of absorbent cotton. — N. F. Mucilage of Linseed. A mucilage of linseed may be pre- pared as follows: Linseed, whole av.oz. 3 Distilled water, warm fl.oz. 14^ Macerate for 6 hours, agitating fre- quently and strain. — D. The linseed should be rinsed off, be- fore using, in a sieve with running water, to remove adherent dust. Mucilage of Quince Seed. (Mucilage of Cydonium.) Quince seed, whole gr. 40 Distilled water fl.oz. 4 Macerate the quince seed for Yz hour, in a covered vessel, with the distilled water, frequently agitating. Then drain the liquid through muslin without pres- sure. This preparation should be freshly made, when required for use. — N. F. Appendix and U. S. P. 1880. Mucilage of Salep. Salep, fine powder gr. 72 Water, cold fl.oz. 1 x /i Water, boiling fl.oz. 14^2 Place the powder into a flask contain- ing the cold water and shake until the powder is well divided. Then add the boiling water and shake the mixture continuously until it has cooled to 25 deg. C. or below this temperature. The cooling may be hastened by frequent and brief immersion of the flask in cold water. This preparation should be freshly made, as required for use. If sugar or syrup is prescribed in the same mixture with mucilage of salep, it is preferable to triturate the required quantity of powdered salep with either of the former, as the case may be and then to rapidly add the proportionate amount of boiling water. — N. F. and Germ. Pharm. Mucilage Sassafras Pith. (Mucilago Sassafras Modullae.) Sassafras pith gr. 36 Water fl.oz. 4 Macerate the pith in the water dur- ing 3 hours, and strain.— N. F. The mixture should be stirred fre- quently during maceration. The pith should be broken into small pieces be- fore adding the water. The preparation should be freshly made, when wanted. Mucilage of Starch. Starch gr. 200 Distilled water fl.oz. 16 Triturate the starch with water gradu- ally added until a smooth paste is form- ed, then boil for a few minutes, con- stantly stirring. — Brit. Pharm. 1885. Mucilage of Tragacanth. I. Tragacanth, in pieces av.oz. 1 Glycerin av.oz. 3 Water, to make av.oz. 16^ Mix the glycerin with 12 fluidounces of water in a tared vessel, heat to boil- ing, add the tragacanth, and let it mac- erate for 24 hours, stirring occasionally. Then add the remainder of the water, beat the mixture so as to make it of uni- form consistence, and strain it forcibly through muslin. — U. S. P. II. Tragacanth, pure, powder... gr. 100 ALohol fl.dr. 3 Distilled water, to make. . .fl.oz. 16 Mix the gum with the alcohol in a bottle, agitating thoroughly, then add the water, and shake immediately. — Brit. Pharm. Mulls, Plaster and Salve. Plaster mulls and salve mulls were introduced in dermatologic practice by Dr. Unna. Plaster mulls may be made in the following manner : Place a fine, moist linen cloth on an 250 STANDARD FORMULARY OF ironing board, which is not too thickly padded, over this a sheet of gutta- percha, which must not be too thin, however, about 6 to 8 inches wide, and over this a large sheet of smooth gauze, which must not come in contact with the moist linen. Then the gauze is made to adhere to the gutta-percha by ironing over with a flat iron, which re- quires some practice, for if the iron is too hot, and remains too long on the gauze, the gutta-percha will become per- forated; on the other hand, when not hot enough, the two will not adhere permanently. This fabric is then spread and fastened on a plaster board, and coated several times with the plaster mass, which is dissolved in petroleum benzine in the proportion of I to 4, or even 1 to 3. To prepare the plaster, heat a piece of caoutchouc for Yz hour to a tempera- ture of 200 deg. C. After cooling, cut into pieces as small as possible, place in an iron or brass mortar into a steam bath, add to 3 parts of caout- chouc, 1 part of oleic acid and 3 parts of resin and knead thoroughly, at intervals, until no more lumps of caoutchouc are visible. This is dis- solved, as above stated, in 3 or 4 parts of petroleum ether (gasolin) to 1 part of the mass. With this solution the gauze is to be coated several times, avoiding presence of any fire. When dry, a piece of starched gauze is to be laid on the face. The National Formulary states that salve mulls are ointments of high fusing points, containing the desired medicinal agent and spread upon gauze or "mull" in a manner similar to the ordinary spread plasters. Although these mulls are more conveniently produced with the aid of special mechanical appliances, it is quite practicable to prepare them on a limited scale as follows : A sheet of moistened parchment paper is spread smoothly on a table top, the excess of moisture wiped off with a cloth, and a corresponding piece of un- sized gauze is evenly stretched upon the parchment paper and held in place by thumb tacks. The previously melted and partly cooled ointment is then spread evenly on the gauze by means of a broad, flat, bristle brush, and when a sufficient layer has been applied in this way, the surface is smoothed by the aid of two flexible spatulas, heated by im- mersion in hot water, wiped dry, and used alternately to expedite this opera- tion. A smooth surface having been at- tained, the thumb tacks are removed, and the salve mull is withdrawn from the parchment paper, this operation be- ing facilitated by wrapping the uncoated end of the gauze over a flat stick of wood. The salve mull is then suspended on a string in a cool room, and when thoroughly chilled, it is covered with paraffin paper and rolled up. Salve mulls differ therefore from plaster mulls in not having a gutta- percha backing, the mass is made with- out caoutchouc, it melts more readily, and is applied to the mull in a melted condition. The most suitable base for preparing salve mulls is a mixture of suet and lard, in variable proportions, with the occasional addition of wax or lead plas- ter, this depending on the nature of the medicinal component or the intended use. The following formulas may serve as examples : I. Zinc Salve Mull (10 per cent.) : Zinc oxid part 1 Benzoinated lard parts 2 Benzoinated suet parts 7 II. Salicylic Acid Salve Mull (10 per cent.) : Salicylic acid part 1 Benzoinated lard part 1 Benzoinated suet parts 8 III. Corrosive Mercuric Chlorid Salve Mull (2/10 per cent.) : Mercuric chlorid parts 2 Alcohol parts 50 Benzoinated lard parts 50 Benzoinated suet parts 900 PHARMACEUTICAL PREPARATIONS. 251 IV. Creosote-Salicylic Acid Salve Mull (20:10 per cent.) : Salicylic acid parts 10 Creosote parts 20 Yellow wax parts 5 Benzoinated suet parts 65 Oakum, Medicated. Medicated oakum is sometimes used as a surgical dressing instead of cotton. It is somewhat cheaper than jute and much cheaper than cotton. Carbolated (5 per cent.) 'and mercuric chlorid (1:1000) oakums are used mostly. These may be prepared like the corres- ponding jutes. See Jutes. Oil of Amber. (Oleum Succini.) I. Crude oil of amber (U. S. P. 1850) : Mix amber in powder with an equal weight of sand, introduce into a glass retort or flask, which is to be only half filled, then distil on a sand bath, with a gradually increasing heat. The dis- tillate will separate into an acid liquid, an oil, and a concrete acid impregnated with oil. The oil is to be separated from the other matters and kept in well- stoppered bottles. II. Rectified oil of amber (U. S. P. 1870) : Crude oil of amber pint 1 Water pints 6 Mix in a glass retort or flask, and distil until 4' pints of water have passed with the oil into the receiver; then separate the oil from the water and pre- serve in a well-stoppered bottle. There is probably but little genuine oil of amber on the market and those requiring a true oil should prepare it themselves. Oil, Angleworm. Angleworms, freed from ad- herent dirt part 1 Olive or other bland fixed oil parts 2 Macerate for three days in a warm place, then strain or filter. Presumably cottonseed or lard or other bland fixed oil to which a very small amount of Dippel's animal oil has been added will serve equally well, Oil of Ants. (Ameisen Oel.) Raw linseed oil, also spirit of formic acid are dispensed for this. Oil of Arnica, Infused. Prepare like the infused oils (see Oils, Infused), but using 1^4 av. ounces of cut arnica flowers for the herb and adding to the flowers 75 grains of coarsely powdered turmeric root. — D. modified. Oil, Baunscheidt. (Compound Oil of Euphorbium.) Baunscheidt was a German charlatan who claimed to cure rheumatic and other diseases by means of what he called a "lebenswecker," i. e., "awaken- er" or "revulseur." This consists of a number of sharp-pointed needles set in a bed of hard rubber. By means of a spiral spring arrangement these needles are driven into the skin over the seat of pain, not deep enough to draw blood, while into the wounds produced is rub- bed the "Baunscheidt oil." This is an irritating substance and produces papu- lar eruptions similar to those produced by croton oil. The effect is that of a powerful counter-irritant. In medicine this treatment is known as acupuncture. Formulas for the oil are as follows: Cantharides, powder gr. 48 Euphorbium powder gr. 80 Olive or cottonseed oil fl.oz. 4 — H. modified. Macerate for 7 days and filter. II. Cantharides, powder gr. 12 Euphorbium, powder gr. 64 Mezereum, cut fine gr. 128 Alcohol, absolute fl.dr. 4 Ether fl.dr. 6 Olive or cottonseed oil fl.oz. 4 Mix the two powders, alcohol and ether in a closed vessel, macerate for about 3 days, agitating occasionally ; then add the oil, macerate again for about 3 days, strain, heat the colature gently so as to expel the ether, and filter,— H. modified. 252 STANDARD FORMULARY OF III. Croton oil fl.dr. i Cantharidal oil fl.oz. i l / 2 Olive or cottonseed oil fl.oz. 2 l / 2 — D. modified. Oil of Belladonna, Infused. Prepare from belladonna leaves by the process under Oils, Infused, which see. Oil, British. (Oleum or Linimentum Britannicum. — Oil of Stone.) There are many formulas for this preparation. Originally oil of stone was natural rock oil or petroleum and many formulas for imitations of this article were in vogue, in former days when it was scarce, expensive and reputed to possess great medical virtues. The for- mulas for British oil were similar and gradually the two names became to be considered synonymous. When oil of stone is asked for, it may, however, sometimes be the crude petroleum which is desired instead of the mixture known as British oil. The following are the principal for- mulas for British oil: I. Cooley : Oil of turpentine fl.oz. 4 Barbadoes tar fl.oz. 2 Oil of rosemary fl.dr. 1 Oil of origanum fl.dr. 1 II. Formula of Philadelphia College of Pharmacy : Oil of turpentine fl.oz. 4 Linseed oil, raw fl.oz. 2 Oil of amber fl.oz. 1 Oil of juniper fl.oz. 1 Barbadoes tar fl.dr. 6 American petroleum fl.dr. 2 III. Parrish's modification of No. II : Oil of turpentine fl.dr. 4 Linseed oil fl.oz. 6 Oil of amber fl.oz. 2 Oil of juniper m. 30 Barbadoes tar fl.dr. 2 Crude petroleum fl.dr. 2 IV. This mixture has been recom- mended for oil of stone: American petroleum volume 1 Barbadoes tar volume 1 Oil of turpentine volumes 3 Oil of Cade, Factitious. (Empyreu- matic Oil of Juniper.) While oil of cade as such is commer- j daily available and should be used in prescriptions when demanded, there is also a factitious article used for veter- inary applications which is said to be prepared as follows : Pine tar av.oz. iH Oil of juniper wood fl.oz. 7 Olive or other similar fixed oil fl.oz. 7 Gum benzoin, coarse powder.gr. 80 Melt together by the aid of a gentle heat, and strain. Oil, Calendula. (Infused Oil of Cal- endula — Calendulated Oil.) Beringer's formula: Calendula flowers, con- tused av.oz. 1 Ammonia water m. 10 Alcohol fl.dr. 6 Olive oil, pure av.oz. 1 Moisten the flowers with the mixed ammonia and alcohol, place in a suitable container, add the oil, macerate for about 4 days at a temperature of 50 to 70 deg. C. with frequent agitation, ex- press and filter. Oil, Cantharidal or Cantharides. Cantharides, powder av.oz. 3 Olive oil, yellow av.oz. 10 Mix, heat for 10 hours on a boiling water bath, express and filter. — Germ. Pharm. Cottonseed oil may be substituted for the olive oil. Oil, Carbolized. Carbolic acid, crystal part 1 Cottonseed oil parts 19 Parts are by weight. Melt the acid with a gentle heat, and mix it with the oil. — N. F. The carbolized oil of the Germ. Form. is made from 1 part of oil to 49 of olive oil. Oil, Carminative. (Colic Oil.) Oil of spearmint fl.dr. 5 Oil of caraway fl.dr. 2 l /> Oil of cumin fl.dr. 2 l / 2 Oil of fennel ...fl.dr. 2]/ 2 Infused oil of chamomile, to make fl.oz. 16 This is what is desired by Scandina- vians when green oil is asked for, but PHARMACEUTICAL PREPARATIONS. 253 Germans understand by this title the in- fused oil of henbane. Oil of Chamomile, Infused. This may be like any of the infused oils, using German chamomile flowers, whole, and omitting the ammonia water. See Oils, Infused. Oil, Chloroform. Chloroform part i Olive oil part i Parts are by weight. — Germ. Pharm. Oil, Cod-Liver, Aromatized or Palat- able. I. Oil of lemon drops 50 Oil of neroli drops 20 Oil of peppermint drops 10 Vanillin gr. 1 Coumarin gr. 1/10 Cod liver oil fl.oz. 16 Dissolve the coumarin and vanillin in the volatile oils, with the aid of a very gentle heat, and mix the solution with the cod liver oil. — D. II. Cod liver oil may also be made palatable by adding to a pint 2 or 3 fluidrams of a 1 in 10 solution of sac- charin in acetic ether. Volatile oil such as peppermint, cinnamon, wintergreen, etc., may also be added. III. Pavesi's formula: Cod liver oil fl.oz. 16 Roasted coffee, powder. .. .av.oz. 24 Animal charcoal av.oz. T / 2 Place in a well-closed flask, digest on a water bath for one hour, then set aside for 3 days, and filter. — H. IV. Cod liver oil fl.oz. 16 Oil of peppermint .drops 4 Oil of anise drops 8 Chloroform drops 20 — H. V. See also Emulsion of Cod Liver Oil. Oil, Cod-Liver, with Iodin. (Iodized Cod-Liver Oil.) Iodin gr. 8 Chloroform m. 10 Cod liver oil fl.oz. 16 Triturate the iodin with a few drops of oil, then add more of the oil and the chloroform, mix this with the remainder of the oil contained in a bottle, and agitate frequently until dissolved. — D. modified. See also Oil, Iodized. The iodized cod liver oil of the Germ. Form, is made from 1 part of iodin and 1000 of oil (same strength as the above), triturating the iodin with some of the oil, and then agitating frequently until the iodin is dissolved. Oil, Cod Liver, with Iron. (Ferrated Cod Liver Oil.) I. Iron benzoate gr. 70 Cod liver oil fl.oz. 16 Triturate the iron salt with the oil and warm gently until the former is dissolved. The product contains 1 per cent, of the iron salt. — Germ. Form. II. Medicinal soap gr. 60 Solution of iron oxychlorid. fl.oz. 2 Distilled water sufficient Sodium chlorid gr. 90 Cod liver oil fl.oz. 16 Dissolve the soap in 2 fluidounces of water by the aid of heat, also mix the iron solution with 2 fluidounces of water, add the latter liquid gradually to the soap solution (when cold), stirring constantly. Collect the precipitate with- out washing; place between folds of filter paper until tolerably dry, or weigh- ing about 350 grains, place in a porce- lain or enameled iron evaporating dish with the salt and oil, heat on a water bath until solution takes place, and filter. The object of the salt is to ab- stract water from the iron compound and thus facilitate its solution in the oil.— D. This contains about Y / 2 per cent, of ferric oleate. It may be made stronger by using proportionately more of the soap, iron solution and water. The iron oleate may also be prepared from solution of iron tersulfate and solution of sodium oleate (castile soap). III. Ferris chlorid, sublimed gr. 68 Cod liver oil fl.oz. 16 254 STANDARD FORMULARY OF Dissolve the chlorid by triturating in a mortar with the oil gradually added, then filter. Ferric chlorid when perfectly anhy- drous as it is when sublimed and keep in well-closed bottles is soluble in the oil. Oil, Cod Liver, with Iron Iodid. (Eer- ro-Iodized or Iodo-Ferrated Cod- Liver Oil.) Iodin gr. 30 Reduced iron gr. 15 Stronger ether m. no Cod liver oil, to make. . . .av.oz. 16 Triturate the iodin, iron and 1 fluid- ounce of oil in a mortar with the ether until a black mixture results and the iodin and iron have combined ; then add the remainder of the oil, let stand for several days, and filter. The product contains about Yz per cent, of ferrous iodid. — D. Oil, Cod Liver, with Malt Extract. Oil, Cod Liver, Malted. For cod liver oil with malt extract, see Extract of Malt with Cod Liver Oil. Oil, Cod Liver, with Phosphorus. (Phosphorized or Phosphorated Cod Liver Oil.) This may be made by dissolving 1 gr. of phosphorus in 16 fluidounces of cod liver oil by the aid of a gentle heat on a water bath, agitating frequently. This preparation may also be con- veniently prepared by mixing 2 fluidrams of phosphorated oil with 16 fluidounces of cod liver oil. Oil, Cod Liver, with Quinine. This may be prepared by dissolving 64 grains of dry quinine alkaloid in a small amount of pure oleic acid by the aid of a gentle heat, and add enough cod liver oil to make 16 fluidounces. Of course, a ready-prepared quinine oleate may be added directly to the oil. Oil of Conium, Infused. This is prepared like the infused oils, using conium herb. See Oils, Infused. Oil, Eel, Factitious. See Lards, Factitious. Oil of Eggs. This is obtained by subjecting hard- boiled yolk of eggs to pressure, or by extracting hard-boiled yolks with car- bon disulfid. About 1 fluidounce of oil is thus obtained from 16 yolks. The oil deteriorates very readily and must be preserved in dram-vials in a cool, dark place. A factitious article may be prepared as follows : Olive or cottonseed oil fl.oz. 13^2 Cocoa butter av.oz. 2^2 Yellow wax av.oz. y 2 Melt together on a water bath. — H. It may often be replaced by olive, sweet almond, cottonseed or other simi- lar bland fixed oil. Oil, Ethereal. (Oleum Aethereum. — Oil of Wine.) Alcohol fl.oz. 32 Sulfuric acid, U. S. P fl.oz. 32 Distilled water fl.dr. 6 l /2 Ether, stronger sufficient Add the acid slowly to the alcohol, mix them thoroughly, and allow the mixture to stand, in a closed flask, for 24 hours, or until the liquid is clear ; then pour the liquid into a tubulated re- tort of such capacity that the liquid shall nearly fill it. Insert a thermometer through the tubulure, so that the bulb shall be deeply immersed in the liquid and having connected the retort with a well-cooled condenser and also having connected with the receiver a bent glass tube for conducting the uncondensed gases into water, distil, by means of a sand bath at a temperature between 150 and 160 deg. C. until only drops cease to come over, or until a black froth, which forms on the surface, begins to rise in the retort. Separate the yellow ethereal liquid from the distillate and expose it to the air, for 24 hours, in a shallow dish. Then transfer it to a wet filter, and, when the watery portion has drained ofT, wash the oil which is left on the filter with the distilled water which should be as cold as possible. When this also has drained off. mix the PHARMACEUTICAL PREPARATIONS. 255 remaining oil with an equal volume of stronger ether. The oily liquid obtained is what is known as heavy oil of wine, so that ethereal oil is a mixture of equal vol- umes of heavy oil of wine and stronger ether. The product should be preserved in small glass-stoppered bottles in a cool place. — N. F. Ethereal oil of the market is fre- quently known as heavy oil of wine but of course should not be confused with the true heavy oil of wine, which is also obtainable. The commercial ether- eal oil can be had at almost any price and probably consists of heavy oil of wine diluted with more or less ether or alcohol or both to suit the ideas of intending purchasers. As the average yield of oil is about 2 to 2^ per cent, of the alcohol used, it follows that the oil cannot but be an expensive article. It is used pharmaceutically only in the making of compound spirit of ether. Oil, Felon or Secretive. (Malefiz or Ausscheidungs Oel.) Kneipp's : Croton oil part I Sweet almond oil parts 6 Oil of Gladness. This mixture is used in some parts of this country under the above name: Oil of sweet marjoram fl.dr. I Oil of peppermint fl.dr. I Oil of horsemint fl.dr. I Tincture of opium fl.dr. I Tincture of capsicum fl.dr. 4 Ether fl.dr. 2 Alcohol, to make fl.oz. 8 Red sounders, ground gr. 10 Mix, macerate for several days and filter. Oil, Goose. See Lards, Factitious. Oil, Gray. (Oleum Cinereum.) This is a fluid form of mercurial oint- ment employed by Prof. Lang of Vienna for subcutaneous injection. There are two strengths, a stronp - and a mild, one prepared from a strong, the other from a weak, special mercurial ointment. The strong oil is prepared from 9 parts by weight of the strGng gray oint- ment and 4 of olive oil, mixing thor- oughly. It contains nearly 50 per cent, of metallic mercury, and is injected in quantities of 0.1 cc. The weak oil is prepared from 6 parts by weight of mild gray ointment and 4 of olive oil, mixing thoroughly. It con- tains 30 p. c. of metallic mercury, and is injected in quantities of 0.1 cc. The strong "gray lanolin ointment" is prepared from 1 av. ounce of anhy- drous wool fat, 2 av. ounces of metallic mercury, and about 2 to 2Y2 fluidounces of chloroform. The fat and mercury are to be triturated together in a capacious mortar, gradually adding chloroform, until the mercury is well extinguished. Then continue trituration till the chloroform has dissipated. The weak ointment is prepared in the same manner from 1 av. ounce each of anhydrous wool fat and metallic mer- cury and about 10 to 12 fluidrams of chloroform. The strong gray oil may be made di- rectly from the metal by mixing 6 parts by weight of it with 3 of anhydrous wool fat and 4 of olive oil; the weak gray oil from 3 each of metallic mer- cury and anhydrous wool fat and 4 of olive oil. The metal should be tritur- ated with the fat until extinguished, then incorporated with the oil. Oil, Green. Dispense either carminative oil or in- fused oil of henbane. See Oil Carmina- tive and Oil of Henbane, Infused. Sometimes simply the so-called Malaga olive oil is dispensed. Oil, Green "Wonder. This is said to be used in some parts of this country: Venice turpentine av.oz. 4 Zinc sulfate, fine powder gr. 15 Copper acetate, fine pow- der av.oz. i l / 2 Peru balsam gr. 60 Linseed oil lb. 1 Olive oil lb. 1 Warm the two oils, add the turpen- 256 STANDARD FORMULARY OF tine, then the other ingredients, and stir until cold. This is used for scalds, burns, wounds and piles. Oil, Haarlem. (Medicamentum.- - Dutch Drops. — Tilly Drops. — Haarlem Balsam. — Dutch or Hol- land Balsam or Drops. — Silver Balsam or Drops. — Batavia Em- pyreumatic Oil.) I. Hager states that the original Batavian empyreumatic oil was sold as Haarlem oil. It was prepared by the dry distillation of 5 parts each of aloes and myrrh, 2 of olibanum and 50 of olive oil. The preparation current in this coun- try is not made according to the above but always contains balsam of sulfur and oil of turpentine, similar to Nos. II and III. II. Balsam of sulfur, from lin- seed oil part 1 Oil of turpentine parts 3 — H. III. Balsam of sulfur, from lin- seed oil part 1 Oil of turpentine parts 2 Oil of cade parts 4 — H. IV. The following formula is an Am- erican variation : Balsam of sulfur fl.oz. 3 Barbadoes petroleum fl.oz. 1 Oil of amber, crude fl.oz. 1^2 Oil of turpentine fl.oz. 8 Linseed oil, raw fl.oz. 4 Oil of Henbane, Infused. (Oleum Hyoscyami Coctum. — Oil of Hy- oscyamus. — Groen Olje. I. This may be prepared from hen- bane leaves according to the process given under Oils, Infused. II. Henbane leaves, cut moder- ately fine av.oz. I Alcohol fl.dr. 7 Olive oil av.oz. 10 Moisten the leaves with the alcohol, keep in a closed vessel, for several hours, add the oil. heat on a water bath until the alcohol has dissipated, express, and filter. — Germ. Pharm. Oil of Henbane, Compound. (Com- pound Oil of Hyoscyamus. — Bal- samum Tranquillans. — Baume Tranquille.) Oil of wormwood drops 5 Oil of lavender flowers drops 5 Oil of rosemary drops 5 Oil of sage drops 5 Oil of thyme, white drops 5 Infused oil of henbane fl.oz. 8 The Baume Tranquille (Balsamum tranquillans) of the Codex is a more complex preparation, not identical with the above, but possessing about the same properties. — N. F. Oils, Infused. (Olea Cocta or Infusa.) The following is the general process of the N. F. for preparing the so-called infused oils, such as oil of hyoseyamus, oil of chamomile, etc. : The dry herb, moderately coarse (No. 40) powder. av.oz. zVa Alcohol fl.oz. 3 Ammonia water, 10 p. c m. 30 Lard oil av.oz. 8 Cottonseed oil av.oz. 8 Moisten the powdered herb with a sufficient quantity of the alcohol and ammonia water previously mixed, then pack it tightly into a stone or enamelled iron vessel of suitable capacity, pour on the remainder of the ammoniated alco- hol, cover it well, and allow the mix- ture to macerate for 24 hours. Then add 2 av.ounces of the mixed oils, digest, under frequent agitation, during T2 hours, at a temperature between 50 and 60 deg. C, transfer the mixture to a strainer, and express strongly. To the residue, returned to the vessel, add the remainder of the oils, digest and express in the same manner, and unite the expressed portions. This process is a modification of that prescribed by the Germ. Pharm. The alcohol and free ammonia are dissipated during the digestion. Infused oils are usually prepared usually from so-called narcotic plants, but it is known that only a portion of their active constitu- ents is taken up by the oil. PHARMACEUTICAL PREPARATIONS. 257 Oil, Iodized. A redely method of incorporating iodin with oils is the following: Iodin gr. 20 Sodium iodid gr. 5 Glycerin, about drops 5 Triturate thoroughly and incorporate the requisite amount of oil. Oil of Joy. This is said to be used in some parts of this country under the above name: Oil of sassafras fl.dr. 1 Oil of cedar fl.dr. 1 Chloroform fl.dr. 3 Camphor gr. 30 Tincture of quaiac fl.dr. 1 Tincture of capsicum fl.dr. 2 Ammonia water fl.dr. 4 Alcohol fl.oz. 8 Oil, Lily. A preparation which may be sold un- der this name is the following: Cottonseed oil, bleached. .. .fl.oz. 16 Oil of bergamot drops 16 Oil of Origanum. The so-called pure oil of origanum is the red or unpurified oil of thyme (Thymus vulgaris). The so-called com- mercial oil of origanum is the pure oil mixed with oil of turpentine. Oil, Paraffin. (Liquid Petrolatum or Petrolatum Oil.) See Paraffin. Oil, Phosphorated. I. Phosphorus gr. 22 Sweet almond oil, stronger ether, each sufficient Introduce a quantity of the oil into a flask, heat it on a sand bath to 250 deg. C, keep it at that temperature for 15 minutes, then allow it to cool, and filter it. Put 4^2 av.ounces of the fil- tered oil together with the phosphorus, previously well dried with filtering or blottins: paper, into a dry, tared bottle capable of holding about 6 fluidounces, insert the stopper, and heat the bottle in a water bath until the phosphorus is completely melted (occasionally open- ing the bottle to allow the expanded air to escape). Then agitate it until the phosphorus is dissolved, allow it to cool, add enough stronger ether to make the mixture weigh 5 av. ounces, and shake again. Lastly, transfer the solu- tion to small glass-stoppered vials, which should be completely filled and kept in a cool and dark place. — N. F. and U. S. P. 1890. The preliminary heating of the oil is to coagulate albuminous matter which fixed oils contain, also to expel air and traces of water. The ether assists in preservation of the product as well as to render it less disagreeable to the taste. The phosphorus used should be in translucent pieces. The product contains 1 per cent, by weight of phosphorus, or slightly over y 2 gr. in a fluidram. It should be free from any undissolved phosphorus. II. Heat sweet almond oil in a porcelain dish to about 150 deg. C. and keep it at this temperature for about 15 minutes, then let it cool, and filter through pa- per. Put 99 parts by weight into a stoppered bottle capable of holding rath- er more than this amount, and add to" it one part by weight of dry phosphorus. Immerse the bottle in hot water until the mixture has acquired the tempera- ture of 82 deg. C, removing the stopper two or three times to allow the escape of expanded air; then shake until the phosphorus is entirely dissolved. The proportion of phosphorus to oil is 18 grains of the former to 4 av.- ounces of the latter. — Brit. Pharm. Oil of Pumpkin Seed. Pumpkin seed av.oz. 2 Ether av.oz. 2 Beat the seeds in a mortar until thor- oughly broken, then add the ether in small portions at a time, rubbing until well mixed; transfer to a bottle, cork well, and let stand 10 hours; then change to a small funnel or percolator, and pass enough ether through the mass to obtain 2 av. ounces of percolate ; al- 258 STANDARD FORMULARY OF iow it to evaporate in a current of air until it has lost the odor of ether. This is used to expel tapeworm, y 2 ounce being a dose, to be repeated in 2 hours, then followed in 4 hours with castor oil to which 30 to 60 drops of ether may be added. — Eclectic. Oil, Rainworm, Artificial. (Regen- wurm Oel.) The following are used : I. Oil of birch tar part I Rapeseed oil, crude, to make parts 25 — H. II. Linseed oil, raw parts 49 Animal oil part 1 III. Animal oil parts 2 Petroleum parts 5 Rapeseed or other neutral fixed oil parts 150 IV. Cottonseed or other neutral fixed oil, colored with al- kanet root. V. Raw linseed oil. Oil of Rhodium. (Oil of Duty.) True oil of rhodium is distilled from the roots of Convolvulus Scoparius and other species. There are, however, a number of mixtures parading under the name oil of rhodium which are used as baits by rat-catchers, fishermen, and others. Among these mixtures are the following : I. Oil of rose fl.dr. 1 II. Oil of rose drops 20 Sweet almond oil fl.oz. 1 Balsam of copaiba fl.oz. 1 III. Oil of rose fl.dr. I Oil of sandalwood fl.oz. 2^ IV. Oil of rose fl.dr. 1 Sweet almond oil fl.oz. 2 Oil of sandalwood fl.dr. 4 Probably in many instances the oil of rose in the above formulas is replaced wholly or in part by oil of rose gera- nium. Oil, Rue. Kneipp's: This is prepared from the leaves like infused oil of henbane. See Oils, In- fused. Oil, Sage. Kneipp's : This is prepared from the leaves like infused oil of henbane. See Oils, In- fused. Oil, Skunk. See Lards, Factitious. Oil of Spike. True oil of spike is a distillate of the spike lavender plant. The commercial oil of spike which is used so largely for veterinary purposes is, however, a very different article, mixtures of various kinds being used. The most common mixture is Barbadoes tar with about 3 times its volume of oil of turpentine. Sometimes some raw linseed oil is add- ed, also a small amount of crude oil of amber or oil of hemlock is added to partially modify the odor of the turpen- tine. Another mixture which has been suggested is a mixture of 1 fluidounce of amber oil, 2 fluidounces of Barbadoes tar and 16 each of linseed and turpen- tine oils. Oil, St. Johnswort. Kneipp's : This is prepared from the leaves like infused oil of henbane. See Oils, In- fused. Oil of Stone. See Oil. British. Oil of Stramonium, Infused. This is to be prepared from stramo- nium leaves according to the process given under Oils, Infused, which see. Oil of Turpentine, Rectified. Oil of turpentine a convenient quantity. Solution of sodium hy- drate sufficient Shake the oil thoroughly with au PHARMACEUTICAL PREPARATIONS. 259 equal volume of the solution, introduce the mixture into a copper still con- nected with a well-cooled condenser, then distil until about three-fourths of the oil has passed over, and separate the clear oil from the mixture of oil and water in the distillate. The product should be kept in well- stoppered bottles, in a cool place, pro- tected from light.— U. S. P. The above should always be dispensed when oil of turpentine is required for internal use. In the Germ. Pharm. and the U. S. P. 1890, this preparation is made by dis- tillation of the oil with 6 volumes of lime water. Oils, White. See Liniment, Turpentine, Acetic. Oil of Wormwood, Infused. Prepare like the infused oils. See Oils, Infused. Oil-Sugars. (Oleossacharates — Oleo- sacchara — Elaeossachara.) The general process of the N. F. for oil-sugars is as follows: Any volatile oil drop 1 Sugar gr. 30 Triturate the sugar with the oil to a fine powder. This preparation should be freshly made when wanted for use. When Elseosaccharum Anisi, E. Fce- niculi, E. Menthse Piperise, etc., etc., are prescribed, these are to-be prepared from the corresponding essential oils, accord- ing to the above formula. The Germ. Pharm. directs the pro- portions of 1 part by weight of oil to 50 of sugar and- directs 25 drops of oil to be considered equal to 1 grain of oil. But inasmuch as these prepara- tions are used only as adjuvants, the above more convenient formula may al- ways be employed. The Dan. and Norw. Pharms. direct 1 part of oil and 49 of sugar. Ointments. (TJnguenta.) These are mixtures of fatty or fatty and wax bodies, or these combined with 17 other solid or medicinal substances. They are softer than cerates and are in- tended for rubbing (inunction) into the skin. Ointment of Aconite. Extract of aconite leaves. .. .part 1 Lard parts 2 Soften the extract with water or di- luted alcohol and mix well with the lard. — Eclectic. Ointment, Aconitine. Aconitine gr. 10 Oleic acid, pure gr. 80 Lard gr. 410 Rub the aconitine with the acid and gently warm the mixture until dis- solved, then incorporate the lard. — Brit. Pharm. Ointment, Alkaline. Sodium carbonate gr. 120 Tincture of opium fl.dr. 1 Lard av.oz. 1 Triturate the sodium salt to an im- palpable powder, mix with the lard, and then add the tincture.— Eclectic. Ointment, Alkaline, Camphorated. Potassium carbonate gr. 20 Camphor, powder gr. 6 Lard gr. 420 Warm the lard, add the camphor, stir well till dissolved, and mix the potas- sium carbonate. — Eclectic. Ointment of Aluminum Acetate. Unna's : Simple ointment av.oz. 1 Wool fat, hydrous av.oz. 2 Solution of aluminum ace- tate av.oz. 4 (about fl.dr. 30) Mix the ointment and fat, and grad- ually incorporate the solution. — D. Ointment, Ammoniacal. (Gondrat's Pomade.) Lard gr. 240 Suet gr. 160 Sweet almond oil m. 80 Stronger water of ammonia (28 per cent, or concen- trated) fl.oz. 1 Melt the lard and suet together, add the oil, and when the mixture is tol- erably cool, pour it into a wide-mouthed bottle, add the ammonia water, cork 260 STANDARD FORMULARY OF well, and shake occasionally until cold. — Eclectic. This is a slight modification of the formula of the Codex which directs i part each of suet and lard, then add 2 parts of ammonia water, sp. gr. 0.920. This is used as a rubefacient and vesicant. Ointment of Ammoniated Mercury. (Ointment of White Precipitate — Unguentum Hydrargyri Album — Weisse Quecksilber Salbe.) Ammoniated mercury (white precipitate) part 1 White petrolatum parts 5 Wool-fat, hydrous parts 4 Rub the ammoniated mercury to a perfectly smooth paste with about an equal weight of melted white petrola- tum, then add the remainder of the petrolatum melted and the wool-fat and stir the mixture until it congeals. — U. S. P. The Brit, and Germ. Pharms. direct the use of paraffin ointment as the ve- hicle. Ointment, Antimonial. (Tartar Emet- ic Ointment — Ointment of Tartar- ated Antimony — Unguentum Sti- biatum — Autenrieth's Ointment.) Tartar emetic, very -fine pow- der gr. 100 Lard gr. 400 — U. S. P. 1870. The Brit. Pharm. 1885 (not in 1898) directs simple ointment instead of lard. The Germ. Pharm. directs paraffin ointment instead of lard. No water should be employed in ma- king this ointment. Ointment, Astringent. Mutton suet lb. 1 Witch-hazel or sumach leaves, .oz. 2 Melt the suet, boil with the leaves for one-half hour and strain. — Thomsonian (from Comfort's Practice). Ointment, Atropine. Atropine gr. I© Oleic acid, pure gr. 40 Lard gr. 450 Triturate the atropine with the acid and gently warm the mixture until dis solved, then incorporate the lard. — Brit Pharm. and Eclectic. Ointment, Bayberry. Bayberry plaster av.oz. 4 Olive oil fl.oz. 1 Melt the plaster, add the oil, and stir until cool. — Eclectic. This may also be prepared from: Bayberry wax av.oz. 2 Gum turpentine av.oz. 2 Olive oil fl.oz. 1 Ointment of Bayberry, Compound. Bayberry wax av.oz. 1 . Sweet gum av.oz. 1 Suet : av.oz. 2 — Eclectic. Ointment of Bearsfoot. (Ointment of Polymnia.) Polymnia, fresh root part 1 Lard or mutton suet parts 2 Cut the root into small pieces, add the fat, heat , the mixture until water ceases to evaporate, and strain while hot. — Eclectic. Another Eclectic formula for this preparation is the following: Fluid extract of bearsfoot. .av.oz. 1 Lard av.oz. 2 Heat together until vapors cease to escape. Ointment of Belladonna. I. Extract of belladonna leaves. av.oz. y 2 Diluted alcohol fl.dr. 2 Wool fat, hydrous...., av.oz. 1 Benzoinated lard av.oz. 3^2 Triturate the extract with the diluted alcohol until a smooth mixture is ob- tained, with this incorporate "the wool fat, and then add the lard.— U. S. P. II. Fluid extract of belladonna root, Brit. Pharm fl.oz. 3 Benzoinated lard av.oz. 3 Evaporate the fluid extract on a wa- ter bath to Y% av.ounce (165 grains), and then incorporate the lard. 1000 parts of this ointment should contain 6 parts of alkaloids of bella- donna root.— Brit. Pharm. Ointment, Black. (Black Salve.) Thomsonian works directed this PHARMACEUTICAL PREPARATIONS. 261 "black salve," which was the same as "mother salve," but Thomson himself objected to its use. Instead of it, as an application to old sores and ulcers, he recommended beef's gall dried down to the consistence of ointment. Ointment, Blue. (Mercurial Oint- ment, Diluted or Milder — Gray or Neapolitan Ointment — Franz- osen, Reuter or Material Salbe.) Mix 2 parts of mercurial ointment (U. S. P. or 50 p. c.) with 1 part of petrolatum. — U. S. P. The product contains," therefore, 2>Z X A per cent, of metallic mercury. The preparation of the Brit. Form, is made from 1 part of mercurial ointment (Brit. Pharm.) and 2 parts of lard. The ^product contains approximately 16 per cent, of mercury. Ointment of Boric Acid. (Boric Oint- ment.) I. Boric acid, fine powder part 1 Paraffin part 1 White petrolatum . . . ' parts 8 Melt the paraffin, add the petrolatum and heat gently for 10 minutes; then add the hot liquid to the acid, contained in a warm mortar, triturating thorough- ly, and stir the mixture until it con- geals.— U. S. P. In the Brit, and Germ. Pharms., this is made from 1 part of boric acid and 9 parts of paraffin ointment. II. Lister's formula: Boric acid, fine powder part 1 White wax part 1 Paraffin parts 2 Sweet almond oil parts 2 Triturate the acid to a smooth paste with a portion of the oil, melt the par- affin, wax and remainder of the oil to- gether and add the previous mixture. Ointment, Brown. (Mother's Salve — Unguentum Fuscum — TJnguent- um Matris — Mutter Salbe.) Camphorated brown plaster. av.oz. 2 Olive oil av.oz. 1 Suet av.oz. 1 Melt them together, and stir the mass until it is cold. — N. F. Cottonseed or other bland fixed oil could be substituted for the olive oil. Ointment, Burn. Melt yellow wax and burgundy pitch together (no quantities given) and add enough swee. oil to make an ointment. — Thomsonian (from the Materia Med- ica). Ointment, Calamine. (Unguentum Zinci Carbonatis Crudi — Un- guentum Calaminare or Calaminse — Turner's Cerate — Ointment of Zinc Carbonate.) I. Prepared calamine part 1 Simple ointment parts 5 Mix them intimately, by trituration, so as to produce a smooth and homoge- neous ointment. — N. F. II. The calamine ointment of the Brit. Pharm. 1885 (not in 1898) was made with benzoinated lard instead of simple ointment. III. Rademacher's formula for cala- mine ointment : Camphor, powder gr. 55 Litharge av.oz. 1 Armenian bole av.oz. 1 Lead carbonate av.oz. 1 Calamine, prepared av.oz. 1 Yellow wax av.oz. i]/ 2 Lard av.oz. 6 Mix the litharge, lead carbonate, bole and calamine to a smooth paste with a portion of the lard, also melt the wax, to it add the remainder of the lard, add the previous mixture, mix the whole thoroughly, add the camphor and stir occasionally until solid. — D. and H. Ointment, Calendula. (Calendulated Ointment.) I. Beringer's (said to be similar to the homeopathic preparation) : Yellow wax av.oz. *4 Paraffin av.oz. J4 Petrolatum av.oz. 4J4 Fluid extract of calendula flowers fl.dr. 2 Extract of calendula part 1 II. Diluted alcohol., .sufficient to soften the extract. Simple ointment parts 9 — H. 262 STANDARD FORMULARY OF III. It may also be prepared by di- gesting I av.onnce of calendula flowers in 9 av.ounces of simole ointment for about 2 hours, then expressing. IV. Kneipp's : Simple ointment impregnated with the flower and herb of calendula. Ointment, Calomel. Calomel part I Benzoated lard parts g —Brit. Pharm. Ointment, Camphor. Camphor, coarse powder. .. .parts 2 White wax part I Lard parts 6 Melt the wax and lard with a gentle heat, then add the camphor, and stir the ointment until it is cold. — N. F. Ointment, Cantharides or Canthari- dal. I. Cantharides, bruised part i Benzoinated lard parts io Melt the lard, add the cantharides, digest at a temperature of about SO deg. C. for 12 hours, strain through calico, press the residue gently, and stir until cold. — Brit. Pharm. II. Cantharides oil parts 3 Yellow wax parts 2 The Germ. Pharm. also recognizes a cantharidal ointment for veterinary use. See Ointment, Cantharides, Veterinary. — Germ. Pharm. Ointment, Canthardes, Veterinary. Cantharides, moderately fine powder av.oz. 3 Gum euphorbium, moderate- ly fine powder av.oz. V/2 Soft turpentine av.oz. 3 Yellow wax av.oz. V/2 Olive oil av.oz. 3 Lard av.oz. 3 Mix the cantharides, oil and lard, heat on a water bath, and keep warm for 10 hours, stirring occasionally, add the wax and turpentine, and, when melted, re- move from the water bath, add the euphorbium, and stir the mixture fre- quently until cold.— Germ. Pharm. Ointment, Capsicum. Capsicum pods, bruised gr. 120 Spermaceti gr. 60 Olive oil av.oz. 1 Digest on a water bath for 1 hour, stirring occasionally, strain, and allow to cool without stirring. — Brit. Pharm. See also Ointment of Oleoresin of Capsicum. Ointment of Carbolic Acid. (Carbolic or Phenol Ointment.) I. Carbolic acid, crystal gr. 108 White petrolatum av.oz. 8 Melt the petrolatum, add the acid, and stir the mixture until it begins to con- geal. The product contains 3 per cent, of acid— U. S. P. This acid used for making this and other carbolic ointments should be the crystal acid itself or preferably this melted by aid of heat, and then should be added to the melted fat. On no account should an acid liquefied by the aid of alcohol, water, glycerin or other similar liquid be used, as this interferes with the solution of the acid. In the U. S. P. 1890 this ointment contained 5 per cent, of acid and was made with simple ointment as the ve- hicle. II. Glycerin Paraffin ointment av.oz. iy 2 av.oz. io l / 2 Dissolve the acid in the glycerin and incorporate with the ointment. — Brit. Pharm. III. Lister's carbolic salve: Carbolic acid, crystal av.oz. 1 Linseed oil, raw av.oz. 4 Prepared chalk sufficient Mix the acid and oil and add sufficient chalk to make a soft ointment. — D. Ointment, Casein, Unna's. Casein av.oz. 2^ Potassium hydrate gr. 23 Sodium hydrate gr. 5 Glycerin fl.oz. 1 Petrolatum gr. 150 Zinc oxid gr. 36 Carbolic acid gr. 36 Water, to make av.oz. 16 PHARMACEUTICAL PREPARATIONS. 263 Prepare the casein as follows : Take milk from which the cream or fat has been entirely removed, curdle it by the addition of rennet essence, at a tempera- ture of 30 to 40 degs. C. ; collect the coagulum and wash with running water or otherwise until the washings are no longer acid; dry carefully and powder. Dissolve the alkalies in a portion of the water, and in this solution dissolve the casein, add the glycerin and carbolic acid, incorporate the petrolatum and zinc oxid, and finally the remainder of the water. This is recommended by Unna as a vehicle to be used instead of fatty bodies for inunction. Ointment, Chaulmugra or Gynocar- dia. Chaulmugra oil part 1 Paraffin ointment parts 3 Mix together in a mortar or on a tile. — Eclectic. Ointment, Chrysarobin. Chrysarobin gr. 92 Benzoinated lard av.oz. 4 Triturate the chrysarobin with the lard, previously melted, and heat the mixture on a water bath with occasional stirring for 20 minutes, then strain and stir until it congeals. — U. S. P. The directions of the Brit. Pharm. are similar. Triturate 73 grains of chrysa- robin with 4 av.ounces of benzoinated lard previously melted by heat ; con- tinue the heat until the chrysarobin is dissolved and stir until cold. Ointment of Chrysarobin, Compound, Unna's. Chrysarobin gr. 200 Ichthyol gr. 200 Salicylic acid gr. 80 Petrolatum av.oz. 8 — H. Ointment, Clay. See Kneipp's Remedies. Ointment, Cocaine. Cocaine (alkaloid) gr. 20 Oleic acid, pure gr. 80 Lard gr. 400 Triturate the cocaine with the acid, gently warm the mixture till cocaine is dissolved, and then incorporate the lard. —Brit. Pharm. Ointment of Cocculus Indicus. Kernels of cocculus indicus. .gr. 30 Lard gr. 150 Rub up the kernels in a mortar, first alone, then with a small portion of the lard, and gradually add the rest of the lard. An ointment composed of 3 grains of picrotoxin and 144' grains of lard is sometimes used in place of the above. Ointment, Conium. (Ointment of Poison Hemlock.) I. Extract of conium gr. 6© Lard av.oz. 1 Soften the extract with water or di- luted alcohol and add the ointment. — Eclectic. II. Conium juice fl.oz. 11 Wool fat, hydrous av.oz. 4 • Evaporate the juice, on a water bath at a temperature not over 60 deg. C, to one-eighth of its volume, then incor- porate with the wool fat. — Brit. Pharm. Ointment of Copper Subacetate. (Un- guentum JEruginis or Apostolor- um — Egyptian or Apostle Salve.) Copper subacetate (verdi- gris) av.oz. y 2 Rosin av.oz. y 2 Yellow wax av.oz. 2 Lead plaster av.oz. 4 Olive oil av.oz. 9 Olibanum, finest powder. .. .av.oz. 2 Melt the wax, plaster and rosin to- gether and add 7^2 av.ounces of the oil. Intimately mix the verdigris with the remaining oil to a smooth paste, add this mixture to the previous one, stir well, add the olibanum, and stir fre- quently until cool. — H. Another ointment containing verdigris is what is known as green ointment. See Ointment, Green. Ointment, Creosote. Creosote, beech wood av.oz. 1 Paraffin av.oz. 4 Petrolatum, white av.oz. 5 Melt the paraffin and petrolatum to- 264 STANDARD FORMULARY OF gether, add the creosote, and stir until cold. — Brit. Pharm. Ointment, Diachylon. (Lead Oint- ment — Hebra's Ointment — He- bra's Diachylon Ointment.) I. Lead plaster av.oz. I White petrolatum oz. 1 Oil of lavender flowers. . .drops 10 Melt the plaster by applying a gentle heat, add the petrolatum, and mix thor- oughly; then allow the mixture to cool, add the oil of lavender flowers, and stir the ointment until it congeals. — U. S. P. The U. S. P. directs this ointment to be prepared as needed. This ointment is readily decomposed in making it unless great care be exer- cised to apply only a gentle heat ; and it is liable to spoil within a few days after making it. If even only slightly rancid, it will be unfit for use. If a soft grade of petrolatum be substituted for the olive oil in the above, the product will keep quite well and will be equally effi cient. II. When made according to the U. S. P. 1880, this ointment was more nearly like the preparation used by Prof. Hebra of Vienna. The U. S. P._ 1880 formula was 60 parts of lead plaster, 39 of olive oil, and 1 of oil of lavender flowers, corresponding to 1 av.ounce of lead plaster, s l A fluidrams of olive oil, and 10 drops of oil of lavender flowers. III. Lead plaster, Olive oil, each. .equal parts by weight Melt together at a gentle heat, and stir until the mixture has concreted. After standing for several hours, again thoroughly stir the mixture. — Germ. Pharm. This is the preparation recognized by the Germ. Pharm. under the name di- achylon ointment. Lead ointment, Germ. Pharm., is a different preparation; see Ointment, Lead. IV. Hebra's original directions are the following: Litharge av.oz. 4 Water fl.oz. 1 Olive oil av.oz. 20 Oil of lavender flowers fi.dr. 2 Mix the litharge with the water in a capacious vessel, add the olive oil, and heat over a naked flame, stirring con- stantly, until the reddish color has com- pletely disappeared, from time to time adding a small amount of water to re- place that lost by evaporation. Then heat the mixture on a water bath to evaporate the superfluous water. When the ointment no longer foams or effer- vesces, wash it repeatedly with warm water until the washings no longer have a sweet taste. Then beat the ointment so as to dissipate, as much as possible, the retained water. Finally incorporate the lavender oil. — D. Preserve the ointment in not too large wide-mouthed bottles, in a cool place protected from daylight. If quite free from water this ointment is said to keep tolerably well. Ointment, Diabolic. (Unguentum Diabolicum.) Potassium iodid gr. 25 Water m. 20 Mercurial ointment gr. 20 Wool fat, hydrous gr. 100 Lard gr. 280 Dissolve the iodid, in the water and add the other ingredients. — H. Ointment, Eucalyptus. Oil of eucalyptus av.oz. 1 Paraffin av.oz. 4 Petrolatum, white av.oz. 5 Melt the paraffin and petrolatum to- gether, add the oil and stir until cold. —Brit. Pharm. Ointment, Fern. Thomsonian (from the Materia Med- ica) : Take fresh leaves of meadow fern, balm of Gilead buds and gum myrrh, each, equal parts, simmer in fresh but- ter, and strain. Harden with bayberry wax and rosin. Ointment of Figwort. Figwort leaves, fresh av.oz. 4 Lard av.oz. 2 Suet av.oz. 1 PHARMACEUTICAL PREPARATIONS. 265 Heat together until the leaves are crisp, then strain with expression. — Ec- lectic. Ointment of Gallic Acid. Gallic acid part I Benzoinated lard parts 9 Rub the acid with the lard, gradually added, until they are thoroughly mixed, avoiding the use of an iron spatula. — U. S. P. 1880. Ointment, Green. This is sometimes used under the above name : Verdigris, fine powder part 1 Resin cerate parts 15 Add the powder to the cerate, pre- viously melted at a gentle heat, and stir until it concretes. For another ointment containing ver- digris, see Ointment of Copper Subace- tate. Another green ointment is bay- berry ointment. See Ointment, Bay- berry. Ointment, Healing-. (Thomson's Salve — Thomson's Healing Salve.) Thomsonian (from the Guide) : Yellow wax oz. 4 Salt butter oz. 4 White turpentine oz. 6 Balsam of fir oz. 3 Another formula mentions fresh but- ter instead of salt butter, and still an- other 2 ounces of turpentine. Ointment of White Hellebore. (Oint- ment of Veratrum Album.) White hellebore (veratrum album), powder av.oz. 1 Lard av.oz. 4 Oil of lemon m. 10 Mix well. — Eclectic. Ointment of Hydrochloric Acid. (Ointment of Muriatic Acid.) Hydrochloric acid fl.dr. 1 Spermaceti ointment av.oz. 1 Melt the spermaceti at a gentle heat and incorporate the acid. — Eclectic. Ointment, Ichthyol. Unna's : Ichthyol gr. 50 Water m. 50 Lard gr. 150 Wool fat, hydrous gr. 250 Triturate the ichthyol with the water and add the other ingredients. — D. Ointment, Ichthyol, Salicylated or Compound. Unna's : Ichthyol .gr. 50 Salicylic acid gr. 10 Lard gr. 220 Wool fat, hydrous gr. 220 — D. Ointment, loci". I. Iodin gr. 2& Potassium iodid gr. 20 Glycerin gr. 60 Benzoinated lard gr. 400 Triturate the iodin and iodid in a glass mortar with the glycerin until dis- solved, then gradually add the lard and mix thoroughly, avoiding the use of a metallic spatula. — U. S. P. This should be freshly made when re- quired. II. The preparation of the Brit. Pharm. is made in the same manner. III. Rademacher's : Iodin gr. 24 Alcohol sufficient Lard gr. 450 Dissolve the iodin in a little alcohol and add the lard. The product contains 5 per cent, of iodin. — H. Ointment, Iodin, Compound. This is very similar to the iodin oint- ment of the present U. S. P. : Iodin gr. 15 Potassium iodid gr. 30 Water m. 30 Lard gr. 480 Rub the iodin and potassium iodid with the water until both are dissolved, then with the lard, gradually added, un- til well mixed.— U. S. P. 1870 and Ec- lectic. Ointment, Iodoform. Iodoform gr. 50 Lard gr. 450 Triturate the iodoform thoroughly with about twice its weight of lard, then gradually incorporate the remainder of the lard. This preparation should be freshly made, when required. — U. S. P. »-66 STANDARD FORMULARY OF The disagreeable odor of the iodo- form may be neutralized or overcome by adding a few drops of almost any volatile oil; oil of sassafras is very sat- isfactory. The Brit. Pharm. uses yellow paraf- fin ointment instead of the lard. Ointment of Ipecac. Ipecac, fine powder gr. 12© Olive oil fl.dr. 2 Lard Mix well.— Eclectic. .av.oz. Ointment, Lead. See Ointment, Diachylon.-— U. S. P. Unguentum Plumbi (Germ. Pharm.), lead ointment, lead cerate, or ointment of lead subacetate is a different prep- aration, being made as follows : Solution of lead acetate part 1 Wool fat, anhydrous part 1 Paraffin ointment parts 8 Ointment, Lead Acetate. Lead acetate, fine powder... gr. 20 Paraffin ointment gr. 480 —Brit. Pharm. Ointment of Lead Subacetate. See Ointment, Lead. Ointment of Lead Carbonate. (Un- guentum Cerussse.) Lead carbonate gr. 50 Benzoinated lard gr. 450 Triturate the lead carbonate to very fine powder, then add the lard, gradu- ally added, until wel mixed. — U. S. P. 1890. The Brit. Pharm. uses paraffin oint- ment instead of the lard. The preparation of the Germ. Pharm. is made from 3 parts of the carbonate and 7 of paraffin ointment. Ointment of Lead Carbonate, Cam- phorated. (Unguentum Cerussae Camphoratum.) Camphor, fine powder gr. 23 Ointment of lead carbonate, Germ. Pharm av.oz. I Mix the camphor thoroughly with a portion of the ointment and then add the remainder of the ointment. — Germ. Pharm. Ointment, Lead, Compound. (Mayer's Ointment.) Olive oil av.oz. 10 Gum turoentine av.oz. 2 Yellow wax av.oz. 1 Butter, unsalted av.oz. 1 Red lead av.oz. 4 Honey av.oz. 3 Camphor, powder av.oz. 2 Melt the wax and turpentine together, add the butter and oil, heat nearly to boiling, and add gradually, with con- stant stirring, the red lead, continuing the heat and the stirring until the mix- ture becomes black or brown ; allow to cool, and when nearly cold add the honey and camphor, stirring until the latter is dissolved. — Eclectic. Ointment of Lead Iodid. Lead iodid gr. 50 Benzoinated lard gr. 450 Triturate the lead iodid to very fine powder, then rub with the lard, gradu- ally added, until well mixed. — N. F. Appendix and U. S. P. 1890. The Brit. Pharm. uses yellow paraffin ointment instead of the lard. Ointment, Lead Subacetate. (Oint- ment of Glycerite of Lead Sub- acetate.) Glycerite of lead subacetate. av.oz. 1 Paraffin ointment, white. .. .av.oz. 5 —Brit. Pharm. Ointment of Lead Tannate. (Ungu- entum Phembi Tannici — Ungu- entum ad Decubitum.) Tannic acid part 1 Solution of lead subacetate. parts 2 Lard parts 17 All parts by weight. Triturate the acid and solution to a smooth mixture, and incorporate the lard. — Germ. Pharm. Ointment, Marjoram. (Meiran or Mairan Butter.) Sweet marjoram, coarse powder av.oz. 3^ Alcohol fl.oz. 3 Ammonia water m. 40 Lard av.oz. 16 Moisten the herb with the mixed al- cohol and ammonia, place in a suitable vessel and close tightly; after 12 hours, PHARMACEUTICAL PREPARATIONS. 267 melt the lard, add the moistened herb, digest the whole at a temperature of 50 to 60 deg. C. for 5 to 6 hours, agi- tating frequently, and express. — D. Ointment, Marshmallow. (Althsea Ointment — Yellow Ointment — Unguentum Flavum.) Turmeric, powder gr. 150 Lard av.oz. 8J4 Yellow wax av.oz. y 2 Resin av.oz. y 2 Digest the turmeric in the lard for half an hour over a water bath, then add the wax and the resin previously melted together, melt the whole together and strain the ointment— Germ. Pharm. (1st). Ointment, Mercurial. (Unguentum Hydrargyri or XJng. Hyd. cin- ereum.) I. Mercury (metal) av.oz. 8 Benzoinated lard av.oz. 4 Prepared suet av.oz. zVa Oleate of mercury, 25 p. c. . .gr. 140 Triturate the oleate in a warm mor- tar, add the mercury gradually by means of a pipette and when the globules are divided and distributed, set it aside for about 15 minutes. Melt the lard and suet, allow the mixture to cool partially, add about y 2 av. ounce of it to the mer- curial mixture, and continue the tritura- tion until globules of mercury are no longer visible under a lens magnifying 10 diameters. Then add the remainder of the lard and suet and mix thoroughly. The product is to be assayed and 100 parts of ointment should yield not less than 49 parts of mercury.— U. S. P. The above is an excellent process for the extinction of the mercury. A sub- stance which is superior to mercury oleate as an extinguisher of mercury is hydrous wool fat; see formula No. IV. The U. S. P. mercurial ointment con- tains one-half mercury, that of many of the other pharmacopeias only one-third mercury. The above may be made into one-third preparation by using corres- pondingly less mercury, e. g., 4 av. ounces each of mercury, lard and suet and 72 grains of oleate of mercury. The above ointment may be diluted for counter sale by addition of petrola- lum as directed in Ointment, Blue, which see. II. Mercury av.oz. 16 Lard av.oz. 16 Mutton suet av.oz. 1 Triturate together until metallic glob- ules cease to be visible. — Brit. Pharm. III. Mercury av.oz. 5 Olive oil gr. 65 Mutton suet av.oz. 3^ Wool fat, anhydrous av.oz. Y\ Lard av.oz.5..dr. 4^ Triturate the oil and wool fat to- gether, then incorporate the mercury by trituration, adding the metal gradually in small portions, not adding a further portion of metal, until the previous por- tion is no longer discernible to the naked eye. Now melt the lard and suet together and when nearly cold, incor- porate with the previous mixture. — Germ. Pharm. IV. Mercury av.oz. 5 Wool fat, hydrous av.oz. 5 Lard av.oz. 4 White wax av.oz. 1 Triturate the mercury with the wool fat until the former is extinguished, then add the lard and wax, previously melted together and allowed to cool. — Austr. Pharm. Ointment of Mercury Amnionio- Chlorid. See Ointment of Ammoniated Mer- cury. Ointment, Mercurous Chlorid. See Ointment, Calomel. Ointment, Mercury, Compound. Mercurial ointment parts 10 Yellow wax parts 6 Olive oil parts 6 Camphor parts 3 Mix the wax, oil and ointment by the aid of a gentle heat, add the camphor, and triturate until cold. — Brit. Pharm. 268 STANDARD FORMULARY OF Ointment of Red Mercuric Iodid. Red mercuric iodid gr. 20 Benzoated lard gr. 480 —Brit. Pharm. Ointment of Mercuric Nitrate. (Cit- rine or Yellow Ointment — Ungu- entum Hydrargyri Nitratis or Citrinum — Unguentum Citrinum — Gelbe Quecksilber Salbe — Mer- curial Balsam.) I. Mercury (metal) av.oz. 1 Nitric acid av.oz. 2.y 2 Lard av.oz. io^4 Heat the lard, in a glass or porcelain vessel, to a temperature of 105 deg. C. ; then withdraw the heat, gradually add 1 av. ounce of nitric acid, and, when the reaction moderates, reapply the heat, un- til effervescence ceases. Then allow the mixture to cool to about 40 deg. C. In the meantime dissolve the mercury in the remainder of the acid with the aid of sufficient heat to prevent the solution from crystallizing and add this solution to the lard mixture. When the mass begins to congeal, stir it thoroughly with a wooden spatula until it is of a bright citrine color. Avoid contact with metallic utensils. — U. S. P. The nitric acid should be of the strength of the U. S. P., viz., 68 p. c. of absolute acid; the lard should be real hog's lard, not a composition. This formula is an excellent one, al- though other fatty bodies such as lard oil, cod liver oil, neatsfoot oil, etc., have been suggested in place of the lard. The U. S. P. 1890 used lard oil. The main point to secure a good prod- uct is not to allow the temperature to exceed that specified. England has made the excellent suggestion to use 470 grains of red mercuric oxid instead of the mercury (being purer and more easily weighed), dissolving this in the acid, adding gradually to the mixture of lard and acid at a temperature of 60 deg. C. (instead of 40), stirring till cool, and adding Y av. ounce of glyc- erin (to prevent ultimate friableness). II. Mercury av.oz. I Nitric acid fl.oz. 3 • Lard av.oz. 4 Olive oil av.oz. 7 Dissolve the mercury in the acid with- out the aid of heat, agitating gently from time to time. Heat the lard and oil together on a sand bath, so that the mixture when transferred to a heated earthenware jar, capable of holding ten times the quantity, shall be at a tempera- ture of about 145 deg. C. Add the cold mercurial solution very gradually, stir- ring constantly to promote disengage- ment of the fumes. After frothing has ceased, the mixture, which should have a temperature of not less than 90 deg. C, must be kept stirred until cold. The product should be firm in consist- ence and have a pale lemon color. — Brit. Pharm. Judged from the American standpoint, this formula is faulty in not having a portion of the acid added to the lard and oil before adding the mercurial solu- tion, in excessive acidity of the product, and in directing an excessive tempera- ture. Ointment, Mercuric Nitrate, Diluted. Ointment of mercuric nitrate. part 1 Petrolatum, yellow parts 4 —Brit. Pharm. Ointment, Mercuric Oleate. Oleate of mercury, precip- itated part 1 Benzoated lard parts 3 —Brit. Pharm. Ointment of Bed Mercuric Oxid. (Ointment of Bed Precipitate — Unguentum Hydrargyrum Bu- brum.) I. Red mercuric oxid, very fine powder gr. 50 Water m. 50 Wool fat, hydrous gr. 200 Petrolatum gr. 200 Triturate the oxid with the water un- til the mixture is perfectly smooth and absolutely free from gritty particles, then add the wool fat in divided por- PHARMACEUTICAL PREPARATIONS. 269 tions and incorporate thoroughly with the petrolatum. — N. F. Avoid contact with metallic utensils. II. Brit. Pharm: Red mercuric oxid, very fine powder part I Paraffin ointment, yellow. . .parts 9 III. Germ. Pharm. also uses 1 of oxid and 9 of paraffin ointment. The first formula is the best, the prod- uct being the smoothest. Ointment of Yellow Mercuric Oxid. I. Yellow mercuric oxid gr. 50 Water m. 50 Wool fat, hydrous gr. 200 Petrolatum gr. 200 Triturate the oxid with the water un- til the mixture is perfectly smooth, then add the wool fat in divided portions and incorporate thoroughly with the petrolatum. — U. S. P. Avoid contact with metallic utensils. In making an ointment of yellow oxid of mercury, the oxid may also be first triturated to a smooth paste with a small amount of a bland fixed oil (olive, sweet almond, paraffin) before adding the vehicle. II. Improved Ointment of Yellow Mer- curic Oxid or Unguentum Hydrar- gyric Oxidi Flavi Meloriatum : Yellow mercuric oxid, fresh- ly prepared part 1 Wool fat, hydrous parts 2^ Distilled water sufficient Petrolatum, soft, pure, enough to make parts 10 Prepare the oxid by dissolving 63 grains of pure mercuric chlorid and 24 grains of pure sodium hydrate each separately in a little distilled water, add- ing the mercuric solution to the other with constant stirring, collecting the pre- cipitate on a white filter, and washing with distilled water until absolutely free from chlorids. Allow the precipitate to drain, transfer the magma to a porce- lain mortar, and triturate in its moist state, adding a small quantity of distilled water if necessary to make a thin paste. Then add first the wool fat, triturating to a perfectly smooth mixture, then gradually incorporate the petrolatum. — Cin. Acad. Pharm. This ointment contains 10 per cent, of mercuric oxid and is perfectly free from grit. Weaker ointments may be pre- pared as desired by the physician. The 2 per cent, ointment, the kind usually prescribed, may be made by mixing the 10 per cent, with petrolatum in the pro- portion of 50 grains of the former to 200 of the latter. —Brit. Pharm. III. Yellow mercuric oxid, very fine powder part 1 Petrolatum, yellow parts 9 —Brit. Pharm. IV. Pagenstecher's ointment of yellow mercuric oxid or ophthalmic oint- ment (Unguentum Ophthalmicum) : Yellow mercuric oxid gr. 3 Ointment of rose water gr. 100 -D. Ointment, Mezereum. Fluid extract of mezereum. .fl.oz. 1 Lard av.oz. 2> l A Yellow wax av.oz. ^2 Melt together the lard and wax with a moderate heat, add the fluid extract, and stir the mixture constantly until the alcohol has evaporated; then remove from the source of heat and continue stirring until cool.— U. S. P. 1880. Ointment, Nerve. . Bittersweet root bark parts 2 Wormwood part 1 Chamomile part 1 Moisten with hot water, put into por- poise oil or any kind of soft animal oil, and simmer over a slow fire for 12 hours. Strain and add 1 ounce of oil of turpentine for each pound of oint- ment. — Thomsonian (from the Guide and the Materia Medica). Ointment of Nitric Acid. Olive oil fl.oz. 1 Lard gr. 60 Nitric acid m. 10 Melt the lard at a gentle heat, add the 270 STANDARD FORMULARY OF oil, and stir in the acid with a glass rod until the mixture stiffens.— Eclectic. Ointment, Nutgall. (Ointment of Galls — Gall Ointment.) Nutgall, No. 80 powder av.oz. 1 Simple ointment av.oz. 4 Rub the nutgall with the lard, gradu- ally added, until well mixed. The use of metallic utensils should be avoided. — U. S. P. The Brit. Pharm. uses benzoated lard instead of simple ointment. Ointment of Nutgall and Opium. (Gall and Opium Ointment.) Nutgall ointment gr. 925 Opium, verv fine powder... gr. 75 —Brit. Pharm. Ointment of Oleoresin of Capsicum. Oleoresin of capsicum av.oz. 1 Yellow wax av.oz. Yz Benzoated lard av.oz. 4 Melt the lard and wax at a low tem- perature, add the oleoresin, mix thor- oughly, and, if necessary, strain through muslin. Stir until cold. — Brit. Pharm. As a counter-irritant, the ointment will bear dilution from three to six times. Ointment, Ophthalmic, Pagenstech- er's. See Ointment of Yellow Mercuric Oxid, No. IV. Ointment, Ophthalmic, St. Yves'. (Compound Ophthalmic Ointment — St. Yves' Ophthalmic Balsam.) Red mercuric oxid gr. 36 Zinc oxid gr. 12 Camphor gr. 10 Sweet almond oil gr. 20 Yellow wax gr. 48 Lard gr. 280 The lard and wax should be melted together, the zinc and mercuric oxids should be rubbed to a perfectly smooth mixture with a portion of this mixture, the remainder should be added, and then the camphor previously dissolved in the oil by the aid of a gentle heat. — Germ. Pharm. (1st). Ointment, Paraffin. Several pharmacopeias (but not the U. S. P.) now recognize what is termed paraffin ointment which is used as an ointment vehicle instead of simple oint- ment when a non-absorbent vehicle is desired or required. This preparation is a mixture of a hard with a soft or liquid paraffin. Hard paraffin (usually called simply paraffin, also paraffin wax) does not make a smooth mixture with soft paraffin (petrolatum), and hence paraffin ointment is liable to lack homo- geneity. Ceresin or beeswax would make a smoother mixture than hard paraffin. I. Paraffin parts 3 Petrolatum parts 7 Melt together in a shallow evaporat- ing dish; as the liquid cools, triturate constantly, until, when cold a uniform plastic ointment is produced. — Brit. Pharm. When the paraffin ointment is used as the vehicle for white substances, such as zinc oxid, lead carbonate, etc., it should be prepared with the white vari- ety of petrolatum; when used in col- ored ointments it should be prepared with the yellow variety of petrolatum. The proportions of paraffin and pe- trolatum in this ointment may be varied to meet the exigencies of climate and prevailing temperature. II. Paraffin, hard part 1 Paraffin oil (liquid petrola- tum) parts 4 This should melt at a temperature be- tween 40 and 50 deg. C. — Germ. Pharm. III. Paraffin oil (liquid petrola- tum) parts 7 Yellow wax parts 3 Melt the wax, add the oil, and stir until cool. — Eclectic. Ointment of Pepper. (Ointment of Black Pepper.) Black pepper, fine powder, .av.oz. 1 Pine tar fl.oz. 4 Soot av.oz. 1 Lard av.oz. 4 Melt the lard and tar together, then PHARMACEUTICAL PREPARATIONS. 271 add the soot, and finally the pepper; stir frequently until cool. — Eclectic. Ointment, Pine and Lanoline. Petrolatum, white ...... .av.oz. 1^2 White wax !. . .av.oz. Ya Wool fat, hydrous . , . gr. 390 Oil of pinus sylvestris (oil of Scotch fir or oil of pine needles) fl.dr. 1 Oil of juniper berries : .m. 15 Melt the solid ingredients on a water bath, allow to cool partially, stir in the oils, and continue stirring until a uni- form smooth ointment is formed. A pleasant ointment for eczema, scab- ies, etc.— Cine. Acad. Pharm. Ointment of Poke. Poke leaves, collected just before ripening of the berries av.lb. 1 Lard av.oz. 4 Alcohol fl.oz. 4 Yellow wax av.oz. y 2 Mix all, simmer slowly until the leaves are crisp, and express through linen. An ointment is sometimes made by mixing 90 grains of powdered poke leaves or root or of the extract with 1 av. ounce of lard. — Eclectic. Ointment of Potassium Cyanid. Potassium cyanid gr. 6 Sweet almond oil fl.dr. 1 Cold cream av.oz. 1 Mix well. — Eclectic. This is used as an application to the sound skin in neuralgia. Ointment of Potassium Iodid. Potassium iodid gr. 50 Potassium carbonate gr. 3 Water m. 50 Benzoinated lard gr. 400 Dissolve the two potassium salts in the water by trituration, then gradually incorporate the lard. — N. F. and Brit. Pharm. This preparation should be freshly made as required. The Germ. Pharm. directs 40 parts of potassium iodid, l / 2 of sodium hypo- sulfite, 30 of water and 330 of lard. Ointment of Potassium Sulfuret. (Ointment of Potassium Sulfid.) Sulfurated potassa (sulfuret of potash) gr. 60 Sodium carbonate gr. 60 Lard av.oz. 1 Triturate the two salts to an impalpa- ble condition and incorporate the lard. — Eclectic. This is used in ringworm, itch, and other cutaneous diseases. Ointment, Pyrogallol, Comp. Unna's. (Compound Pyrogallic Acid Oint- ment.) Pyrogallic acid parts 5 Salicylic acid parts 2 Ichthyol parts 5 Petrolatum, yellow parts 88 — H. Ointment, Resin. I. Resin, powder av.oz. 2 Yellow wax av.oz. 2 Olive oil av.oz. 2 Lard av.oz. i]/ 2 Melt the resin and wax together, add the oil and lard, strain and stir until cold. — Brit. Pharm. II. The corresponding preparation of the Germ. Pharm. is called Basilicon Ointment (commonly known as Koe- nig's Salbe) and is prepared as follows : Soft turpentine av.oz. 1, Mutton suet av.oz. 1I/2 Resin av.oz. 1 V2 Yellow wax av.oz. ij4 Olive oil .av.oz. 4>4 The above are somewhat softer than the resin cerate or basilicon ointment of the U. S. P. See Cerate, Resin. Ointment, Resorcin, Compound. ("Soothing Ointment.") Resorcin parts 6 Zinc oxid ' parts 6 Bismuth subnitrate parts 6 Oil of cade parts 12 Paraffin parts 10 Petrolatum .parts 25 Wool fat, hydrous parts 32 Triturate the resorcin, zinc oxid, and bismuth subnitrate with a small quan- tity of the wool fat until a perfectly smooth mixture is obtained. Incorpor- ate this with the remainder of the wool fat, add the paraffin and petrolatum pre- 272 STANDARD FORMULARY OF viously melted together, and lastly the oil of cade. — N. F. Preserve in containers protected from the light. Ointment of Rose Water. (Cold Cream — Unguentum Aquae Rosae — Unguentum Leniens or Emol- liens or Refrigerans — Creme Ce- leste.) Spermaceti av.oz. 2 White wax av.oz. 2 Sweet almond oil av.oz. 9^ Stronger rose water fl.oz. 3 Borax, fine powder gr. 35 Reduce the spermaceti and white wax to fine shavings and melt them at a moderate heat, add the oil and stir, con- tinuing the heat until the mixture is uniform; then gradually add the rose water, previously warmed and in which the borax has been dissolved, stirring the mixture rapidly and continuously until it congeals and becomes of uni- form consistence. — U. S. P. Objection has repeatedly been made to the presence of borax in this oint- ment as this chemical reacts with many substances with which cold cream is frequently combined. Borax is of ad- vantage only to assist in combining the rose water with the fats. The U. S. P. 1880 directed no borax ; neither does the Brit, or Germ. Pharm. The present U. S. P. directs that if the ointment is to be used as a vehicle for metallic salts, the borax should be omitted. The Brit. Pharm. directs 2 av. ounces each of white wax and spermaceti, 12 av. ounces of sweet almond oil, 9 fluid- ounces of stronger rose water, and 12 minims of oil of rose. The Germ. Pharm. directs 1^4 av - ounces of white wax, 2 of spermaceti, 14^4 of sweet almond oil, 7 of water, and 14 drops of oil of rose. Ointment, Rosemary, Comp'd. (Un- guentum Nervinum — Aromatic Ointment.) Yellow wax av.oz. 1 Expressed oil of nutmeg. . .av.oz. 1 Mutton suet av.oz. 4 Lard av.oz. 8 Oil of rosemary fl.dr. 4' Oil of iuniper berries fl.dr. 4 Melt the wax and suet, add the lard and nutmeg oil, stir till melted, allow to cool, then add the two volatile oils, and stir until well mixed. — Germ. Pharm. Ointment, Salicylic Acid. I. Salicylic acid, powder gr. 10 Paraffin ointment, white. .. .gr. 490 —Brit. Pharm. II. The following is used sometimes in this country: Salicylic acid gr. 40 Tincture of benzoin m. 80 Petrolatum gr. 160 Simple ointment gr. 200 Dissolve the acid in the tincture, and, having previously mixed the other in- gredients, incorporate the solution, with the mixture. Ointment of Shepherd's Purse. (Un- guentum Bursas Pastoris, Rade- macher's.) Shepherd's purse herb, freshly gathered part 1 Lard parts 2 Contuse the shepherd's purse to a pulp, add it to the melted lard, and care- fully heat the mixture over a direct flame until the moisture has all evapor- ated.— D. and H. Ointment, Simple. (Ointment — Oint- ment of Lard, U. S. P. 1860.) I. White wax part 1 Benzoinated lard parts 4 Melt the wax, add the lard and heat gently until liquefied ; then stir the mix- ture until it congeals. — U. S. P. In the former editions of the U. S. P., this preparation was made with yellow wax. When made with the latter, it keeps better than when made with white wax. II. White wax av.oz. 2 Benzoated lard av.oz. 3 Sweet almond oil fl.oz. 3 Melt together and stir constantly until cool.— Brit. Pharm. 1885. There is no corresponding preparation in the Brit. Pharm. 1898. III. The corresponding preparation PHARMACEUTICAL PREPARATIONS. 273 of the Germ. Pharm. is called Unguen- tum Cereum or Wax Ointment and is prepared from 7 parts of olive oil and 3 of yellow wax. Ointment of (Wood) Soot. (Unguent- um Fuliginis.) Wool soot, very fine powder. part 1 Lard parts 4 Used for burns, tinea capitis, and other cutaneous affections. — Eclectic. Ointment, Spermaceti. Spermaceti av.oz. 2^2 White wax av.oz. 1 Sweet almond oil av.oz. 9 Benzoin, coarse powder. .. .av.oz. *4 Melt together the spermaceti, wax and oil, add the benzoin, continue the appli- cation of heat for 2 hours, frequently stirring the mixture, then strain, and stir the ointment constantly until cold. — Brit. Pharm. Ointment, Stavesacre. (Unguentum Staphisagrige.) Stavesacre seeds, crushed. . .av.oz. 2 Yellow wax av.oz. 1 Benzoated lard av.oz. 8^2 Digest the seed with the lard on a water bath for 2 hours, strain and press through calico, add the wax, heat gently until the wax is melted, and stir the mixture until cold. — Brit. Pharm. Ointment of Stramonium. Extract of stramonium leaves gr. 5© Diluted alcohol m. 25 Wool fat, hydrous gr. 100 Benzoinated lard gr. 325 Triturate the extract with the diluted alcohol to a smooth paste, with this in- corporate the wool fat, then add the lard, and mix thoroughly. — U. S. P. Ointment of Stramonium, Compound. Bittersweet root bark av.oz. 1 Stramonium leaves av.oz. 1 Cicuta leaves av.oz. 1 Belladonna av.oz. 1 Yellow dock root av.oz. 1 Venice turpentine av.oz. 1 Lard av.oz. 8 Alcohol sufficient Bruise the leaves and roots, cover with alcohol, allow to digest at a mod- erate heat for 4 hours, add the lard, continue the heat until the leaves are crisped, strain through linen, add the turpentine and stir until cold. — Eclectic. Ointment of Strychnine. Strychnine (alkaloid) gr. 20 Oleic acid, pure gr. 120 or sufficient to dissolve the alkaloid. Simple ointment gr. 360 — Eclectic. Ointment, Sulfur. Sublimed sulfur parts 3 Benzoinated lard parts 17 Rub the sulfur with the lard, gradu- ally added, until well mixed. — U. S. P. The Brit. Pharm. directs 1 part of finely sifted sublimed sulfur and 9 parts of benzoated lard. Ointment, Sulfur, Alkaline. Washed sulfur gr. 100 Potassium carbonate gr. 50 Water m. 25 Benzoinated lard gr. 320 Rub the sulfur with the potassium carbonate and the water, gradually add the lard, and mix thoroughly. — N. F. Appendix and U. S. P. 1880. Ointment, Sulfur, Compound. (Wil- kinson's Ointment — Hebra's Itch Ointment — Unguentum Cadini.) I. Precipitated calcium car- bonate parts 2 Sublimed sulfur parts 3 Oil of cade parts 3 Green soap parts 6 Lard parts 6 Mix the lard with the soap and oil, then gradually incorporate the sulfur and precipitated calcium carbonate. — N. F. The above is Hebra's modification of Wilkinson's ointment. Sometimes birch tar is used for the oil of cade and petrolatum for the lard. II. Sulfur av.ov. 1 White hellebore, powder gr. 57 Potassium nitrate gr. 8 Soft soap av.oz. 1 Poke ointment av.oz. 3 Oil of bergamot m. 15 — Eclectic. STANDARD FORMULARY OF Ointment of Sulfur Hypochlorite. The following has been used under the above name: Sulfur sublimed gr. 60 Oil of bitter almond m. 10 Lard gr. 420 Sulfur chlorid m. 8 Mix the first three ingredients, then quickly incorporate the chlorid. Ointment of Sulfur Iodid. Sulfur iodid gr. 20 Glycerin gr. 20 Benzoated lard gr. 460 Triturate the iodid with the glycerin in a slightly warmed mortar until a smooth paste results, gradually add the lard and stir until cold. — Brit. Pharm. Ointment, Sulfur, Red, Lassar's. (Red Salve.) Vermillion (red mercuric sulfid) part 1 Sulfur, sublimed parts 25 Petrolatum, yellow parts 74 Oil of bergamot part 1 — D. Ointment of Sulfuric Acid. Sulfuric acid fl.dr. 1 Lard av.oz. 1 Mix in a glass or porcelain mortar. — Eclectic. Ointment of Tannic Acid. Tannic acid av.oz. 1 Glycerin av.oz. 1 Simple ointment av.oz. 3 Dissolve the acid in the glycerin with the aid of a gentle heat, then mix the solution thoroughly with the ointment in a mortar, avoiding the use of iron uten- sils.— U. S. P. Ointment, Tar. (TJnguentum Picis Liquidee.) Pine tar av.oz. 5 Yellow wax av.oz. i l / 2 Lard av.oz. 3^2 Melt the wax, add the lard, and, to the melted mixture, add the tar, previ- ously warmed, and incorporate thor- oughly; then strain through muslin, and stir until congealed. — U. S. P. This preparation is not as satisfactory as that of the U. S. P. 1880 which was made from equal parts of suet and tar, the suet being melted, the tar added, the whole strained, and then stirred while congealing. The preparation of the Brit. Pharm. is made from 5 parts of tar and 2 of yellow wax. Ointment, Tar, Compound. Oil of tar parts 4 Tincture of benzoin parts 2 Zinc oxid . , parts 3 Yellow wax parts 25 Lard parts 32 Cotton seed oil parts 35 Melt the ^ellow wax and lard with the cottonseed oil at a gentle heat. Add the tincture of benzoin, and continue heating until all the alcohol has evapor- ated. Then withdraw the heat, add the oil of tar, and finally the zinc oxid, in- corporating the latter thoroughly, so that on cooling, a smooth, homogeneous ointment may result. — N. F. Ointment, Tartar Emetic. See Ointment, Antimonial. Ointment of Thymol. Thymol part 1 Alcohol part 1 Paraffin ointment parts 9 Dissolve the thymol in the alcohol, and incorporate with the ointment.— Ec- lectic. Ointment of Tobacco. I. Extract of tobacco gr. 60 Alcohol fl.oz. 1 White wax av.oz. l / 2 Lard av.oz. 4^2 Dissolve the extract in the alcohol, then add the wax and lard previously melted together, and continue the heat until all of the alcohol has been evap- orated. — Eclectic. This large amount of alcohol is un- necessary : only so much should be used as will soften the extract. It is directed that the ointment may also be prepared by heating together 8 av. ounces of fresh tobacco leaves, 2 av. ounces of lard, 2 fluidounces of alcohol, and Ya av. ounce of yellow wax, until the leaves are crisp, then straining. PHARMACEUTICAL PREPARATIONS. 275 II. Tobacco leaves lb. y 2 Yellow dock root lb. i Lovage root lb. i Soft water gall. 2 Lard, fresh lb. 2 Yellow wax oz. 4 Burgundy pitch oz. 4 Bruise the leaves and roots, which should be fresh, in a mortar, add the water, boil one hour, strain with ex- pression, evaporate liquid to the consist- ency of a thick syrup, add the other in- gredients, and continue a gentle heat until all the moisture has evaporated. Thomsonian (from the Materia Med- ica). Ointment, Turpentine. I. Gum turpentine, Yellow wax, Oil of turpentine, each, equal parts by weight. Melt the turpentine and wax together at a gentle heat, add the oil and stir until cold. — Germ. Pharm. II. Oil of turpentine fl.oz. 1 Resin, coarse powder gr. 54 Yellow wax av.oz. z / 2 Lard av.oz. y 2 —Brit. Pharm. 1885. Ointment, Veratrine. Veratrine (alkaloid) gr. 20 Sweet almond oil gr. 30 Benzoinated lard gr. 450 Rub the veratrine with the oil to a smooth paste, then gradually add the laid, and mix thoroughly. — N. F. The Brit. Pharm. directs 10 grains of veratrine, 40 of pure oleic acid, and 450 of lard. Rub the veratrine with the acid, gently warm the mixture until the alkaloid is dissolved, and incorporate the lard. Ointment, Wax. White wax oz. 4 Spermaceti oz. 3 Olive oil pint 1 — Thomsonian (from the Materia Med- ica). 18 Ointment of Wild Indigo. (Ointment of Baptisia.) Fluid extract of wild in- digo fl.oz. 5 Butter av.oz. 2^ Yellow wax av.oz. Y^ Tallow gr. 165 Melt the fats together, add the fluid extract, and continue heating carefully until all the alcohol and water have evaporated, meanwhile stirring frequent- ly; allow to cool, stirring from time to time till nearly solid. — Eclectic. Instead of the fluid extract of wild indigo, a corresponding amount of "solid" extract may be used ; this should be softened with water or diluted alco- hol after which the fats in melted state should be incorporated with it. Ointment, Witch Hazel. (Hamamelis Ointment.) Fluid extract of witch hazel leaves m. 50 Wool fat, hydrous gr. 420 —Brit. Pharm. Ointment, Wool Fat. Wool fat, anhydrous parts 4 Water part 1 Olive oil part 1 Melt the fat on a water bath at a gentle heat, incorporate the water and then the oil. — Germ. Pharm. Ointment, Zinc, Comp'd. (Wilson's Ointment — Wilson's Zinc Oint- ment.) Zinc oxid av.oz. 3 Benzoin, fine powder av.oz. l / 2 Lard av.oz. 12^2 Digest the benzoin with the lard, on a water bath for one hour, stirring con- stantly; then strain, incorporate the oxid, and stir until cool. — H. Ointment, Zinc, Mild. Olive oil av.oz. 4 Spermaceti av.oz. V/z White wax gr. 495 Zinc oxid av.oz. l / 2 Morphine sulfate gr. 15 Benzoic acid gr. 15 Oil of rose drops 3 Prepare like Ointment of Zinc Oxid, Compound, which see. — Eclectic. 276 STANDARD FORMULARY OF Ointment, Zinc Oleate. Zinc sulfate, pure av.oz. 2 Castile soap, white, shav- ings av.oz. 4 Distilled water, boiling, Petrolatum, white, each sufficient Dissolve the zinc sulfate in 4 fluid- ounces of distilled water and the soap in 40 fluidounces of water. Mix the solutions, collect the precipitated zinc oleate, wash it with hot distilled water until the washings afford little or no reaction for sulfate, dry on a water bath, mix with an equal weight of the paraffin previously melted, and stir till cold. — Brit. Pharm. Ointment of Zinc Oxid. (Commonly called Zinc Ointment.) Zinc oxid, very fine pow- der av.oz. 3 Benzoinated lard av.oz. 12 Rub the oxid, which must be free from gritty particles, with an equal weight of melted benzoinated lard, and with this incorporate the remainder of the lard, previously melted. If neces- sary, strain the ointment while warm and stir thoroughly until it congeals. — U. S. P. Manufacturing chemists now make a very fine grade of zinc oxid suitable for preparing this ointment ; on no account should a cheap, inferior grade of oxid be used as this always contains gritty particles. In the U. S. P. 1890, the ointment was made by sifting the oxid through a fine sieve into the melted lard, the mix- ture then being stirred till congealed. The Brit. Pharm. directs 3 of zinc oxid and 17 of benzoated lard. The Germ. Pharm. directs 1 part of the oxid to 9 of lard. Ointment of Zinc Oxid, Compound. Olive oil av.oz. 4 Spermaceti av.oz. 1^2 White wax av.oz y 2 Zinc oxid gr. 380 Benzoic acid gr. 15 Morphine sulfate gr. 6 Oil of rose drops 3 Triturate the zinc oxid, benzoic acid, morphine sulfate and olive oil to a smooth paste, add this to a melted mix- ture of the wax and spermaceti, stir almost constantly till cool, and then add the oil of rose. — Eclectic. Ointment of Zinc Stearate. Zinc stearate, fine powder, White petrolatum, equal parts by weight. To the petrolatum, melted on a water bath, add the stearate. Continue the heat until the mixture becomes smooth, then stir while cooling until it congeals. — U. S. P. Ointment of Zinc Sulfate. Zinc sulfate part 1 Butter, fresh .'.parts 6 Rub the zinc sulfate to an impalpable powder and add the ointment. — Eclectic. Oleates. (Oleata.) While the oleates themselves are true chemical compounds the preparations known as oleates and recognized by the U. S. P. and N. F. are mixtures of these oleates with excess of oleic acid. These oleates may be divided into two classes, metallic and alkaloidal, the for- mer being prepared by solution of a metallic oxid, the latter by solution of an alkaloid, in pure oleic acid. The method of preparation of these oleates is to triturate the alkaloid or oxid, preferably sifting the latter first through a fine sieve, with the acid in a mortar to a smooth paste, then stirring until combination or solution is effected. Sometimes application of heat is recom- mended but this is not advisable and if used at all should not exceed 40 deg. C. Triturating the alkaloid with the acid in a warmed mortar is to be recom- mended. The oleic acid for these preparations should be the purest obtainable. It is difficult to free this acid entirely from stearic and palmitic acids, but a very good article is now commercially avail- able. The presence of these foreign acids makes a decided difference in the consistence of the oleate produced. These oleates are used in different PHARMACEUTICAL PREPARATIONS. 277 strengths indicating the percentage by weight of metallic oxid or of alkaloid present in the finished product. Any oleate can be reduced to a weaker oleate b) r adding the proportionate amount of oleic acid or of fatty vehicle, if latter be preferred. The oleates intended to be used for the physiological or systemic effects of the base, as quinine, morphine and mercuric oleates, should be diluted with oleic acid, or with purified wool fat; the oleates intended for surface medication should be diluted with lard or petrolatum. These oleates are unstable prepara- tions, becoming rancid quite readily. The weaker the preparation, the more readily it undergoes change ; and when made by the application of warmth the decomposition is facilitated. It there- fore follows that the precipitated or normal oleates keep the best, and that it is advisable to have these on hand and to dilute them, as required, to the desired strength. The dilution should be with oleic acid, lard, etc., as de- scribed above for dilution of oleates. The normal oleates are prepared adding an aqueous solution of a salt of the base to a solution of sodium or potassium oleate, collecting the precipi- tate, washing out the alkaline salt with warm or hot water (for mercuric oleate use only warm water), and then freeing from excess of water. The commercial nomenclature of the normal oleates of metallic bases is pe- culiar. For example, normal mercuric oleate is* said to be 28.3 per cent, strength, maining 28.3 per cent, of oxid. But of course it contains no free oxid of mercury. What is meant is that if 28.3 parts by weight of mercuric oxid be converted into a soluble mercuric salt and then be precipitated with sodium or potassium oleate solution, the collected, washed and dried mercury oleate should weigh 100 parts. In the case of the alkaloidal oleates, the percentage given indicates the pronortion of base present in the compound. The preparations known as ointments of oleates are oleates reduced with lard, petrolatum, paraffin ointment, simple ointment, wool fat, etc. The various ointments of alkaloids (aconitine, atro- pine, cocaine, veratrine) of the Brit. Pharm. are now prepared by dissolving the alkaloid in oleic acid and then add- ing lard, and hence these are examples of ointments of oleates. See also Oint- ment of Zinc Oleate (Brit. Pharm.) which is a mixture of equal parts of precipitated zinc oleate and petrolatum, and Ointment, Mercuric Oleate (Brit. Pharm.), a mixture of 1 part of pre- cipitated mercuric oleate and 3 parts of lard. Oleate of Aconitine. Aconitine (alkaloid) gr. 33 Oleic acid, pure .fl.oz. 4 Or mix in the proportion of 1 part by weight of aconitine to 49 by weight of acid. Triturate the aconitine with a small portion of the acid in a mortar, then in corporate the remainder of the acid, and stir the mixture frequently until the alkaloid is dissolved. The market affords a variety of aconi- tines made by different processes, by different manufacturers, and of greatly different potency. Only the pure crys- tallized or crystallizable alkaloid, having all the characters demanded by the U. S. P. should be used.— N. F. Oleate of aconitine should never be applied with the unprotected hand or fingers. A pencil or little mop should be used. Oleate of Ammonium, Liquid. See Liniment, Ammonia. Oleate of Atropine. Atropine (alkaloid) gr. 33 Alcohol m. 35 Oleic acid, pure fl.oz. 2 Olive oil . . .• fl.dr. 15 Triturate the alkaloid with the alco- hol, add about an equal volume of oleic acid, and after warming the mortar stir until the alcohol has evaporated, add the remainder of the acid and continue STANDARD FORMULARY OF stirring until the atropine is dissolved ; then add the olive oil. — N. F. The product contains 2 per cent, by weight of atropine. Oleate of Cocaine. Cocaine (alkaloid) gr. 82 Alcohol m. 85. Oleic acid, pure fl.oz. 2 Olive oil fl.dr. 15 Prepare like oleate of atropine. — U. S. P. Oleate of Lead. See Plaster, Lead. Oleate of Mercury. I. Yellow mercuric oxid, very fine powder av.oz. 1 Distilled water fl.oz. 1 Oleic acid, pure, to make. . .av.oz. 4 Triturate the oxid with the water in a tared mortar, add 3 av. ounces of acid and mix thoroughly, warm the mortar to a temperature not exceeding 50 deg. C, stir occasionally till the water has evaporated, then add, if necessary, oleic acid to make 4 av. ounces and mix thor- oughly.— U. S. P. Avoid contact with metallic vessels. Keep the oleate in tightly stoppered bottles. This oleate will be more or less dense according to the purity of the oleic acid; the purer it is, that is the freer it is from palmitic and stearic acids, the thinner it is. Of course only the very purest obtainable oleic acid should be employed. While the U. S. P. directs the application of warmth to facilitate solution and combination of the oxid, this is not necessary nor is it advisable. Combination can be effected by mixing the oxid and acid in a mortar, and stir- ring occasionally, being careful to break down any lumps of oxid which may have formed. The cold process requires more time than the warm but the for- mer yields a product which keeps longer. The preparation of the U. S. P. is what is denominated as a "25 per cent, oleate of mercury," as it contains 25 per cent, by weight of mercuric oxid. The preparation of the U. S. P. 1880 was a 10 per cent, oleate and this is the strength intended, as a rule, by physi- cians when none is specified. The U S. P. 1890 had a 20 per cent, prepara- tion. Other strengths, such a 5 per cent, or 15 per cent, may be made by diluting the 20 or 25 per cent, prepara- tion with oleic acid. There is also on the market what is known as "precipi- tated or normal oleate of mercury," which is stated to represent 28.3 per cent, of mercuric oxid. While the other oleates of mercury consist actually of mercuric oleate dissolved in an excess of oleic acid, the normal oleate is the true oleate without the excess of oleic acid. This normal oleate can be pre- pared only by precipitation as follows : Yellow mercuric oxid. . . ._. . .gr. 175 Nitric acid, U. S. P gr. 150 Solution of sodium oleate. fl.oz. 16 Distilled water sufficient To the oxid contained in a small evaporating dish add the nitric acid, then 2 fluidounces of distilled water, and heat until the oxid is dissolved, adding, if necessary, to complete solution, a few more drops of acid, but as little as pos- sible for the purpose. Dilute this with 2 pints of distilled water, add this to the sodium oleate solution, stirring con- stantly. Collect the precipitate and wash several times with luke warm dis- tilled water to remove the sodium nitrate. If solution of potassium oleate be used instead of solution of sodium oleate, 150 grains of mercuric oxid and 130 grains of nitric acid must be used for 1 pint of the solution. The normal oleate of mercury may be diluted to weaker strengths by adding to 100 grains the following amounts of oleic acid (Edel's table) : To make 5 p. c. oleate add 466 gr. oleic acid. To make 6 p. c. oleate add 371 gr. oleic acid. To make 7 p. c. oleate add 304 gr. oleic acid. PHARMACEUTICAL PREPARATIONS, 279 To make 8 p. c. oleate add 254 gr. oleic acid. To make 9 p. c. oleate add 214 gr. oleic acid To make 10 p. c. oleate add 183 gr. oleic acid. To make 12 p. c. oleate add 136 gr. oleic acid. To make 14 p. c. oleate add 102 gr. oleic acid. To make 15 p. c. oleate add 89 gr. oleic acid. To make 16 p. c. oleate add yj gr. oleic acid. To make 18 p. c. oleate add 56 gr. oleic acid. To make 20 p. c. oleate add 41 gr. oleic acid. See also Ointment, Mercuric Oleate. II. Brit. Pharm. formula for mercuric oleate (precipitated or normal only being recognized) : Mercuric chlorid, pure. . . . .av.oz. 1 White castile soap, powder. av.oz. 2 Oleic acid, pure fl.dr. 1 Distilled water, boiling. .. .sufficient Dissolve the chlorid in 10 fluidounces of the distilled water; triturate the oleic acid with the soap, and dissolve the mixture in 11 fluidounces of the distilled water. Mix the two solutions, boil for 10 minutes, set aside for the mercuric oleate to deposit, decant the supernatant liquid, wash the precipitate with hot dis- tilled water until the washings give lit- tle or no reaction for chlorid, and dry on a water bath. Oleate of Morphine. Morphine (alkaloid) gr. 86 Oleic acid, pure fl.oz. 4 Triturate the morphine to fine powder, add to the oleic acid, and dissolve by the aid of a gentle heat. The above makes a preparation con- taining 5 per cent, of alkaloid by weight. If stronger preparations are desired, relatively greater proportions of alkaloid must be used. A 10 per cent, oleate, for instance, would require the use of 172 grains of morphine. Oleate of Quinine. Quinine (alkaloid) gr. 137 Oleic acid, pure fl.oz. 1 Or mix in the proportion of 1% av. ounces of alkaloid to 4 fluidounces of acid ; or in the proportion of 1 av. ounce of alkaloid to 3 av. ounces of acid. Triturate the quinine with the acid in a warm mortar with a small quantity of the acid to a smoth paste, then add the remainder of the acid, previously warmed, and stir frequently until the quinine is dissolved. — N. F. The above makes a preparation con- taining 25 per cent, of alkaloid; prepara- tions containing 10 per cent, and 5 per cent, of alkaloid are also common. A 10 per cent, preparation may- be made by dissolving 184' gr. of alkaloid in 4 fluidounces of acid, or y 2 av. ounce of alkaloid in 4^ av. ounces of acid. A 5 per cent, preparation may be made by dissolving 86 gr. of alkaloid in 4 fluidounces of acid. In the N. F. (2nd edition), which recognized this preparation, it was di- rected that the quinine be first dried at 100 deg. C. until it ceases to lose weight. When the quinine (alkaloid) is not available, it may be prepared as follows : Take 340 grains of official quinine sul- fate, dissolve it in 32 fluidounces of water with the aid of a sufficient quan- tity of diluted sulfuric acid, then pre- cipitate the quinine by means of am- monia water, added, under constant stir- ring, until it is in slight excess. Trans- fer the magma to a close muslin strainer, previously wetted, allow the liquid to drain off, and wash the precipitate with ice cold water, until the washings are practically tasteless, but using not more than about 1 quart of water. Lastly, dry the precipitate. The theoretical quantity of dry qui- nine obtainable from 340 grains of the sulfate is 253 grains. In practice, ap- proximately 250 grains will be obtained. Oleate of Strychnine. Strychnine (alkaloid) gr. 33 Oleic acid, pure fl.oz. 4 280 STANDARD FORMULARY OF Or mix in the proportion of I part by weight of alkaloid with 49 of oleic acid. Triturate together, dissolving by the aid of a gentle heat, if necessary. The product contains 2 per cent, of strychnine by weight. Oleate of Veratrine. Veratrine (alkaloid) gr. 33 Oleic acid, pure fl.oz. 2 Olive oil fl.dr. 15 Triturate the veratrine with about 1^ fluidrams of olive oil, and after warm- ing the mortar, add the acid and con- tinue stirring until the alkaloid is dis- solved, then add the remainder of the oil.— N. F. Oleate of Zinc. The U. S. P. 1890 recognized a 5 per cent, oleate, the N. F. a precipitated oleate. I. Zinc oxid gr. 92 Oleic acid, pure av.oz. 4 Put the oleic acid into a capacious porcelain capsule, gradually add to it the oxid by sifting it through a fine sieve upon the surface of the acid, and incorporate it by vigorous stirring. Set the mixture aside for a few hours, and then heat it on a water bath, frequently stirring, until the oxid is dissolved. — U. S. P. 1890. This preparation contains 5 per cent, of zinc oxid and is of ointment consist- ency. II. Zinc acetate, crystal av.oz. 1 Solution of sodium oleate. . .fl.oz. 42 Water sufficient Dissolve the zinc acetate in 84 fluid- ounces of cold water, filter the solution, if necessary, through a pellet of absor- bent cotton placed in the neck of a funnel, and then mix it slowly, and under constant stirring, with the solu- tion of sodium oleate. Transfer the mixture to a wetted muslin strainer, and when the liquid has drained off, wash the precipitate with water, until the washings are practically tasteless. Last- ly, dry the precipitate, spread on paper. by exposure to dust-free air, without heat. The product contains an amount ol zinc corresponding to about 13 per cent, of zinc oxid. The theoretical yield of zinc oleate obtainable from 1 av. ounce of zinc ace- tate is 2^2 av. ounces ; in practice, about 2*4 av. ounces will be obtained. Zinc oleate, prepared by the above process, is in the form of a soft, white powder, and may be converted into a plaster or ointment by mixing it with such a pro- portion of oleic acid as may be re- quired. See also Ointment, Zinc Oleate. Oleo-Stearate of Zinc. Zinc acetate av.oz. 2V2 Stearic acid, pure av.oz. s l A Oleic acid, pure av.oz. 1 Caustic potassa, pure av.oz. 1 Alcohol fl.oz. 27 Distilled water sufficient Dissolve the oleic and stearic acids in i6 l / 2 fluidounces of alcohol by the aid of heat and the caustic potassa in 11 fluidounces of water by the aid of heat and mix the hot solutions. Strain the -mixture into a caoacious vessel and add to it 27 fluidounces of hot distilled water. Dissolve the zinc acetate in 27 fluidounces of boiling distilled water, filter the solution, if necessary, and pour it, in a thin stream, into the hot alco- holic solution first obtained, with con- stant stirring. Then stir the mixture occasionally until cool, transfer it to a muslin strainer, allow the precipitate to drain, wash it thoroughly on the strainer with distilled water, and dry it in a moderately warm place. When dry. sift it through a very fine sieve. This is similar to Stearate of Zinc, which see. Oleoresins (Ethereal Extracts.) These preparations which may be de- scribed as acetone extracts consisting mainly of oil and resin. Comparatively few drugs are of a character suitable for making these preparations. The general process of the U. S. P. is as follow? : Take any suitable qnantity of PHARMACEUTICAL PREPARATIONS. 281 drug, usually about i av. pound, in about No. 40 powder, put it into a cylindrical glass percolator provided with a stop- cock and arranged with a cover and re- ceptacle suitable for volatile liquids, pack the drug firmly, and percolate slowly with acetone (which should be 99 per cent, pure), added in successive portions, until the drug is exhausted. Recover the greater part of the acetone from the percolate by distillation on a water bath, and having transferred what remains to a suitable dish, allow the remaining acetone to evaporate spontan- eously in a warm place. In the U. S. P. 1890, the drug was extracted with stronger ether. This was Changed in the present pharma- copoeia to acetone (except for cubeb, when alcohol is used) which is a liquid of great solvent power and is exceed- ingly volatile. Its solvent powers are similar to those of both alcohol and ether. All oleoresins should be preserved in well-stoppered bottles. The oleoresins of the market are in- clined to be of somewhat uncertain character. Some are said to be with alcohol, wood spirit, benzin, ligroin, or other menstruum; or, if ether be used, this may be imperfectly evaporated. The oleoresins were formerly classed with the fluid extracts. They are now still frequently known as "ethereal ex- tracts," although of course this name is now inappropriate. Oleoresin of Capsicum. (Ethereal Ex- tract of Capsicum.) Prepare according to the general proc- ess (see Oleoresins). After all the ace- tone has evaporated, pour off the liquid portion, transfer the remainder to a glass funnel provided with a pledget of cotton and when the separated fatty matter (which is to be rejected) has been completely drained, mix the liquid portions together.— U. S. P. Keep the product in a well-stoppered bottle. Oleoresin of Cubeb. (Ethereal Ex- tract of Cubeb — Extractum Cu- bebarum — Extract of Cubeb.) I. Prepare according to the general proc- ess (see Oleoresins), but using the drug in No. 30 powder, and using alcohol as the menstruum instead of acetone. Keep the product in well-stoppered bottles.— U. S. P. This preparation deposits, after stand- ing for some time, a waxy and crystal- line matter, which should be rejected, only the liquid portion being used. II. The corresponding preparation of the Germ. Pharm. called extract of cubeb is prepared as follows: Cubeb, coarse powder av.oz. 20 Stronger ether fl.oz. 65 Alcohol fl.oz. 55 Macerate the drug with a mixture of 39 fluidounces of the ether and 33 of alcohol for 3 days at a temperature of 15 to 20 deg. G, agitate occasionally, and express. Macerate the marc with the remainder of the ether and alcohol as before and again express. Mix the two liquids, filter, and evaporate the filtrate on a water bath to a thin extract. The yield is about 17 or 18 per cent. Oleoresin of Ginger. (Ethereal Ex- tract of Ginger — Piperoid.) Prepare according to the general proc- ess (see Oleoresins), but using the drug in No. 60 powder. Keep the product in a well-stoppered bottle.— U. S. P. Oleoresin of Lupulin. (Ethereal Ex- tract of Lupulin.) Prepare according to the general proc- ess (see Oleoresins), but using the drug without further grinding, and, owing to the large proportion of extractive in the drug, it should be packed dry and yery lightly in the percolator. — N. F. Keep the product in a well-stoppered bottle, 282 STANDARD FORMULARY OF Oleoresin of Male Fern. (Oleorsin of Aspidium — Oleoresina Filicis — Extractum Filicis Liquidum — Liquid Extract of Male Fern — Ethereal Extract of Male Fern — Oleum Filicis Maris — Oil of Fern — Extractum Filicis — Wurmfarn- extrakt or Oel.) I. U. S. P.: Prepare according to the general proc- ess (see Oleoresins), from drug which has recently been reduced to No. 40 powder. Keep the product in well-stop- pered bottles. This oleoresin usually deposits, on standing, a granular, crystalline precipi- tate, consisting of filicic acid, which should be thoroughly mixed with the liquid portion before use. II. The corresponding preparation of the Brit. Pharm., called liquid extract of male fern, is directed to be prepared by exhausting male fern, in No. 20 pow- der, with stronger ether, by percolation, evaporating the ether from the clear percolate on a water bath or by distilla- tion, until an oily extract remains. III. The corresponding preparation of the Germ. Pharm., called extractum filicis, is prepared as follows: Male fern, coarse powder. av.oz. 20 Stronger ether fl.oz. 135 Macerate the drug with 81 fluidounces of the ether for 3 days, at a tempera- ture of 15 to 20 deg. C, agitating occa- sionally, decant the clear liquid, macer- ate the marc with the remainder of the ether for 3 days as before, express, mix the two liquids, filter, and evaporate the filtrate on a water bath to a thin extract free from the odor of ether. Oleoresin of Pepper. (Oleoresin of Black Pepper — Ethereal Extract of Pepper— "Oil of Black Pep- per.") Prepare according to the general proc- ess (see Oleoresins). The spontaneous evaporation of acetone is to be continued until all of it has evaporated, and until the deposition of crystals of piperin has ceased; then the olearesin is to be sepa- rated from the crystals by straining through purified (absorbent) cotton.— U. S. P. Keep the product in a well-stoppered bottle. The commercial article known as "oil of black pepper" is similar to the above ; it is said to be a by-product in the manufacture of piperin. Oleosaccharates. See Oil-Sugars. Opium, Deodorized. (Denarcotized Opium.) Opium, powdered, contain- ing 10 to \oy 2 p. c. of amorphous morphine, any desired quantity. Purified petroleum benzin. .sufficient Macerate the opium for 24 hours in a wide-mouthed, well-closed bottle with enough of benzin to cover it, shaking occasionally. Decant the liquid as closely as possible and repeat the treat- ment with benzin. Again decant the liquid and pour the contents of the bottle into a plain filter contained in a glass funnel which should be well cov- ered; drain, and then percolate the resi- due slowly with benzin until the latter passes without color. Remove the filter cointaining the opium from the funnel and expose the powder to the open air that it may dry thoroughly. — U. S. P. Opium in coarser powder may be de- odorized in the same manner. Deodorized opium should be kept in well-stoppered bottles and should con- tain not less than 10 nor more than 10j£ per cent of anhydrous morphine. In the U. S. P. 1890, the opium was deodorized with stronger ether. Opium, Granulated. Opium dried at a temperature not ex- ceeding 85 deg. C. and reduced to coarse (No. 20) powder. It should yield when assayed not less than 10 nor more than 10^4 per cent of anhydrous morphine. Granuated opi- um of a higher percentage may be brought within these limits by admix- ture with a granulated opium of a lower percentage in proper proportions. — U. S. P. PHARMACEUTICAL PREPARATIONS. 283 Opium, Powdered. Opium, dried at a temperature not exceeding 85 deg. C. and reduced to a very fine (No. 80) powder. Powdered opium, for pharmaceutical ©r medicinal purposes, should yield not less than 10 nor more than 10^ per cent of anhydrous morphine. Any pow- dered opium of a higher percentage morphine strength may be brought with- in these limits by admixture with pow- dered opium of a lower percentage or powdered sugar of milk, in proper pro- portions. — U. S. P. Opodeldoc. For solid opodeldoc, see Liniment, Soap, Camphorated; for liquid opodel- doc, see Liniment, Soap. Ox-Gall, Purified and Inspissated. (Pel Bovis or Tauri — Extractum Fellis Bo vini— Purified Ox Bile.) I. Purified, recognized by U. S. P. 19C0: Fresh ox-gall fl.oz. 6 Alcohol fl.oz. 2 Evaporate the ox-gall in a tared por- celain dish on a water bath to about 2 av.ounces, then add to it the alcohol, mix well, let stand well covered for 3 or 4' days, then decant the clear solu- tion, filter the remainder, and having mixed the liquids and distilled off the alcohol, evaporate the remainder to a pilular consistence. A powder may be obtained by evap- orating to dryness and powdering the residue. II. The inspissated of the U. S. P. 1880, not recognized bv the present U. S. P., was to be made by heating 20 av.ounces of ox-gall to a temperature not exceeding 80 deg. C, straining through muslin, and evaporating the colature on a water bath, in a porcelain capsule, to 3 av.ounces. No. I is to be preferred. III. Ox-gall, fresh fl.oz. 16 Mcohol fl.oz. 8 Evaporate the gall to 4' fluidounces, add the alcohol, shake thoroughly, set the mixture aside until the solid matter has subsided, decant the clear solution, filter the remainder, washing the filter and contents with a little more alcohol. Distil off most of the alcohol from the mixed liquids, evaporate the residue in a porcelain dish, by means of a water bath, to the consistence of thick ex- tract. — Brit. Pharm. Oxymel. (Simple Oxymel.) Acetic acid, 35 p. c fl.oz. 1 Clarified honey, liquefied. .. .av.oz. 9 Distilled water sufficient Mix the honey with the acid and about 10 fluidrams of distilled water, or suffi- cient to produce a preparation having the sp. gr. 1.32. — Brit. Pharm. Oxymel of Squill. I. Vinegar of squill fl.oz. 6 Honey av.oz. 10 Mix them in a tared porcelain capsule or enameled iron vessel, and apply the heat of a water bath until the mixture has been reduced to the weight of 10 av.ounces. Then strain, allow it to cool, and transfer it to bottles, which should be well corked. — N. F. The Brit. Pharm. 1885 directed that the mixture be evaporated until the product, when cold, shall have a specific gravity of 1.32. The Germ.. Pharm. directs a mixture of 1 part by weight of vinegar of squill to be mixed with 2 parts clarified honey, evaporated on a water bath to 2 parts, and strained. II. The Brit. Pharm. 1898 has an im- proved process requiring no evapora- tion, as follows: Squill, bruised av.oz. 1 Acetic acid, 36 p. c fl.dr. 7 Distilled water fl.oz. 2> l A Clarified honey, liquefied. . .sufficient Macerate the squill for 7 days in a mixture of the acid and water, then ex- press strongly, and filter. Mix the prod- uct, which should measure approximate- ly zYa fluidounces, with 10*4 fluidounces of the honey, or enough to produce a preparation having the sp. gr. 1.32. 284 STANDARD FORMULARY OF Papers. (Chartse.) Papers of the U. S. P. consist of paper either saturated with or coated with some substance. They are used by ignition or by application. The U. S. P. also recognizes some test-papers, which are mentioned here. Paper, Asthma (or Antasthmatic Paper). Potassium nitrate av.oz. i$4 Extract of stramonium. .. .av.oz. i Sugar av.oz. 2 Water, hot fl.oz. 10 Dissolve the solids in the water, strain the solution, impregnate white filter pa- per with it, and dry the paper.— Germ. Form. Paper, Cantharides. (Blistering or Vesicating Paper.) White wax av.oz. 2 Olive oil av.oz. 1 Spermaceti ...av.oz. ^4 Balsam of fir .' . . av.oz. % Cantharides, No. 40 powder. av.oz. Ya Water fl.oz. 2>4 Mix all the substances in a tinned vessel, and boil gently for 2 hours, con- stantly stirring. Strain through a wool- en strainer without expressing, and, by means of a water bath, keep the mixture in a shallow, flat-bottomed vessel with an extended surface. Coat strips of sized paper with the melted plaster, on one side only, by passing them success- ively over the surface of the liquid ; when dry, cut the strips into rectangular pieces.— U. S. P. 188Q. Paper, Litmus. Blue. — Impregnate strips of white, un- sized paper, free from wood pulp, but not too porous, with litmus test solu- tion (see Solution, Litmus), and dry the strips by suspending them on strings of clean twine in an atmosphere free from acid or ammoniacal vapors. — U. S. P. Red. — Add to the test solution of lit- mus used to impregnate the paper just sufficient of a highly diluted solution of hydrochloric acid to impart to it a faint red tint. Then with this solution prepare the paper the same as the blue. -U. S. P. Neither red nor blue litmus paper should have a very intense color. Preserve in bottles so as to exclude dust and acid or ammoniacal vapors. Paper, Mustard. I. Mustard, black, No. 6© powd.av.oz. 1 India-rubber gr. 45 Benzin, carbon disulfid, each sufficient Pack the mustard in a conical perco- lator, and gradually pour benzin upon it until the percolate ceases to produce a permanent, greasy stain upon blotting paper. Remove the powder and dry it by exposure to the air. Having mean- while dissolved the rubber in a mixture of 1 fluidounce each of benzin and car- bon disulfid, mix the purified mustard with enough of this mixture to produce a semi-liquid magma and apply this by ■ means of a suitable brush to one side of a piece of rather stiff, well-sized paper, so as to cover it completely, and then allow the surface to dry. — U. S. P. The percolation of the mustard with benzin is for the purpose of removing the fixed oil present in the former. A surface of 9 square inches should contain about 60 grains of mustard. Before the paper is applied to the skin, it should be dipped in warm (not hot) water for about 15 seconds. II. Black and white mustard seeds equal parts by weight Benzol, solution of India rubber, each sufficient Bruise the seeds and extract the fixed oil by percolation with benzol. Dry the residue by exposure to the air in a warm closet and reduce to No. 60 pow- der. Mix 80 grains of the purified mus- tard with 5 fluidrams of the rubber so- lution and spread by means of a suitable brush over about 30 square inches of one side of a piece of a cartridge paper. Allow to dry by exposure to the air. The solution of India-rubber (liquof caoutchouc) is prepared from 2 av.ounce PHARMACEUTICAL PREPARATIONS. 285 of India rubber, cut into fine shreds, and placed in a well-stoppered bottle with a mixture of g l / 2 fluidounces each of benzol and carbon disulfid. Set aside in a cool place and agitate occasionally until the rubber is dissolved. — Brit. Pharm. III. The Germ. Pharm. recognizes this preparation, but gives no process for it, merely describing it as paper covered with finely powdered mustard freed from oil. Paper, Phenolphthalein. This is prepared by impregnating white, unsized paper with the test-solu- tion and drying it. Paper, Potassium Nitrate. (Charta Nitrata — Asthma Paper.) Potassium nitrate av.oz. I Distilled water fl.oz. 4 Dissolve the salt in the water, im- merse strips of white, unsized paper (such as filter or blotting paper) in the solution, and dry them. — N. F. and U. S. P. 1890. Keep the paper in well-closed vessels. This is used as a relief for asthma, the paper being ignited and the fumes thereof inhaled. The directions of the Germ. Pharm. are practically the same; it directs 1 part by weight of potassium nitrate and 5 of water. See also Paper, Asthma. Paper, Turmeric. Impregnate white, unsized paper with tincture of turmeric, and dry it. — U. S. P. This is a test paper which turns brown with alkalies, the yellow color being re- stored by acids. Boric acid, however, even in the presence of hydrochloric acid, turns the color to reddish brown, and this is changed to bluish-black by ammonia. Paraffins. The paraffins are the residues of pe- troleum after the distillation of naphtha, kerosene, etc, These paraffins vary in consistence and melting point from the liquid form to the hard, wax-like form, intermediate forms being of a soft-solid consistency. These different forms ap- pear in the market in various degrees of purity, partially purified ones appear- ing more or less dark yellowish, the purest forms being white or colorless, and nearly odorless and tasteless. The pure forms only are recognized by the pharmacopeia. The liquid form, known as paraffin oil, petrolatum oil, or liquid petrolatum is recognized bv the German, British, French, Norwegian and Danish phar- macopeias and the U. S. P. The U. S. P. requires a sp. gr. of 0.870 to 0.940 at 25 deg. C, the Germ. Pharm. not less than 0.880 at 15 deg. C., the Norw. and Dan. Pharms. 0.895 to 0.905, the Brit. Pharm. 0.885 to 0.890, and the Codex 0.800 to 0.820. The white, wax-like form, called par- affin wax or hard or solid paraffin, or usually simplv paraffin (this term is used in this work) appears in the mar- ket of different melting degrees, viz., 116, 120, 125, 130 and 136 deg. F. (47! 49, 52, 55 and 58 deg. C). The Dan. and Norw. Pharms. do not recognize it at all; the U. S. P. requires a melting point of 125 to 135 deg. F. (51.6 to 57.2 deg. C.), the Brit. Pharm. 130 to 135 deg. F. (54.4 to 57 deg. C), the Germ. Pharm. 165 to 176 deg. F. (74 to 80 deg. C.), and the Codex mentions 44 to 65 deg. C. The intermediate form, the so-called petrolatum, soft paraffin or petroleum ointment appears in the market in white and yellow and darker forms, and of varying soft or semi-solid consistence. In this country the light yellow variety, the so-called amber, is commonly em- ployed, unless otherwise specified. The U. S. P. recognizes two kinds, a yellow and a white, the former being called "petrolatum," the latter "white petrola- tum." They should melt at a tempera- ture between 113 and 118 deg. F. (4. to 48 deg. C). The Brit. Pharm. sped- 286 STANDARD FORMULARY OF fies a melting point of 96 to 102 deg. F. (35.5 to 39 deg. C), or even some- what higher, the Codex a melting point of 104- deg. F. (40 deg. C), the Norw. Pharm. the same, and the Danish Pharm. a melting point of 95 deg. F. (35 deg. C). The dark yellow or brownish forms of petrolatum will suffice for veterinary purposes. Instead of petrolatum, the Germ. Pharm. recognizes a mixture of paraffin wax and liquid paraffin (see Ointment, Paraffin) which melts between 104 and 122 deg. C. (ao to 50 deg. C). The paraffin ointment of the Brit. Pharm. is a mixture of petrolatum and paraffin wax. It melts at about the same temperature as that of the Germ. Pharm. is a mixture of petrolatum and when used as the vehicle of white oint- ments, it should be prepared with white petrolatum; and when used in colored ointments, it should be prepared with yellow petrolatum. Paste, Canquoin's. (Canquoin's Caus- tic—Pate de Canquoin.) Zinc chlorid av.oz. 1 Zinc oxid av.oz. % Wheat flour av.oz. }i Distilled water fl.dr. 1 Mix well so as to make a paste, form into pencils, and dry. Preserve in well-stoppered bottles or vessels containing some quicklime.— Co- dex. The zinc chlorid should be dry. The flour should previously have been dried at a temperature of 100 deg. C. Mixtures of 1 part of zinc chlorid with 2, 3, 4 and 5 parts of wheat flour are also used under the name Can- quoin's Paste, different strengths being used. The zinc chlorid is to be reduced to very fine powder, incorporated with half the flour, made into a thin dough, mixed with the remainder of the flour, roll the mass into flat plate, and roll this into a cylinder. Paste, Carbolic. Listers. Carbolic acid, crystal av.oz. 1 Linseed oil, raw av.oz. 4 Prepared chalk sufficient Dissolve the acid in the oil and add sufficient chalk to make a soft paste. — H. Paste, Currant. (Currant Jelly.) Black-currant paste is used in the London Throat Hospital, and now else- where, as a vehicle, instead of gums, etc., for throat lozenges of certain kinds such as have been used under the direc- tion of Sir Morrell Mackenzie. The directions of the Hospital Phar- macopeia for preparing it are as fol- lows: Take 7 pounds of black currants and 20 fluidounces of water, boil to- gether, crushing the berries with a pes- tle until the mixture is thoroughly pulped, then pass through a sieve and beat into a paste with 3 or 4 pounds of powdered sugar. Red-currant paste may be made in the same manner from red currants. Another formula, probably a better one, is the following: Take fully ripe currants, either red or black, whichever may be wanted ; put them into a suitable dish, bruise them and place them on the fire, stirring con- stantly with a wooden spatula until they become scalding hot, carefully avoiding scorching. When reduced to a pulp, remove from the fire, and strain and express all the juice with a thick flannel cloth or a crash towel. Measure the juice into a clean and bright copper basin, or, still better, a porcelain-lined basin; place upon the fire and boil for 10 or 15 minutes in order to evaporate some of the water; remove the scum, and add 1 pound of sugar for each pint of juice. Stir constantly with a wooden spatula until the sugar is dissolved; then remove the scum and immediately fill the jelly glasses, or other suitable vessels. Pastes, Dermatologic. Dermatologic pastes are medicaments for external use, suggested by the prac- PHARMACEUTICAL PREPARATIONS. 287 tice of noted dermatologists (Lassar, Unna and others). They are ointment- like mixtures of starch, dextrin, zinc oxid, sulfur or calcium carbonate made into a paste with glycerin, soft (green) soap, petrolatum, lard or other fat, med- icated with antiseptic and astringent agents. — N. F. Eight of these preparations are men- tioned by the N. F. Dextrinated paste (see Paste, Dex- trinated) is the vehicle for some of these pastes. See also Paste Pencils. Paste, Dextrinated. Dextrin part I Glycerin part I Distilled water sufficient Dissolve the dextrin in the glycerin and i part of water by heat, and then add enough water, if necessary, to make 3 parts.— N. F. This is a general vehicle for many medicated pastes used in dermatology. Paste, Ichthyol, Unna's. Ichthyol part I Dextrinated paste parts 3 Mix.— N. F. Paste, Kaolin. See Cataplasm of Kaolin. Paste, Betanaphthol. Betanaphthol, fine po gr. 15 Precipitated sulfur gr. 77 Petrolatum gr. 30 Soft soap gr. 30 Triturate the betanaphthol and sulphur with the petrolatum and then incorpor- ate the soft soap with the mixture. — N. F. Paste, London. See Soda with Lime. Paste, Naphthol, Lassar's. Betanaphthol, very fine pow- der part 1 Petrolatum parts 2 Soft (green) soap parts 2 Precipitated sulfur parts 5 Triturate the betanaphthol and sulfur with the petrolatum and then incorpo- rate the green soap with the mixture. — N. F. Paste Pencils. This is a form of medication similar to pastes, but partaking of the form of pencils. See Pencils, Paste. Paste, Resorcinol, Mild, Lassar's. Resorcinol part 1 Zinc oxid parts 2^2 Starch .parts 2^/2 Liquid petrolatum .parts 4 Thoroughly levigate the zinc oxid with enough liquid petrolatum to make a thin paste. Reduce the resorcin to very fine powder, mixed with the starch, and add the mixture to zinc oxid paste, triturating until a uniformly smooth mixture is obtained. Then add the re- mainder of the liquid "petrolatum, and incorporate it thoroughly. — N. F. The Strong Resorcinol Paste contains twice as much resorcinol and 25% more zinc oxid and starch. — N. F. Paste, Vienna. See Potassa with Lime. Paste, Ward's. Thomsonian (from Comfort's Prac- tice) : Black pepper, powder av.oz. 2 Elecampane, powder av.oz. 2 Fennel, powder av.oz. 1 Honey av.oz. 4 Sugar av.oz. 4 Mix and make into a paste. This is an old-time and celebrated remedy for piles. A piece as large as a chestnut is to be taken 4 or 5 times daily. Paste, Wax. Yellow wax av.oz. 2> l A Cocoanut oil av.oz. 1 Wool fat, hydrous av.oz. 1 Borax gr. 55 Distilled water fl.oz. 7*4 Melt the wax, add the oil and wool ^ fat, then gradually incorporate the wa- ' ter in which the borax has previouslj been dissolved. — D. This is used as an ointment vehicle, Paste, Zinc, Lassar's. (Lassar's Zinc* Salicyl Paste.) Salicylic acid, fine powder... gr. 20 Zinc oxid gr. 240 Starch gr. 240 White petrolatum gr. 50© 288 ST A N DA RD FO R M U L ARY OF Thoroughly levigate the zinc oxid with a portion of the petrolatum, then add the acid, starch and remaining pet- rolatum, and triturate until a perfectly smooth mixture is obtained. — N. F. Paste, Zinc, Soft, Unna's. Zinc oxid Part T Calcium carbonate part I Linseed oil part I Lime water P art l Thoroughly levigate the zinc oxid and calcium carbonate with the oil, gradual- ly added, so as to form a perfectly smooth mixture; then incorporate the lime water by trituration.— N. F. Paste, Zinc-Oil, Lassar's. Zinc oxid, pure av.oz. 3 Olive oil av.oz. 2 Mix thoroughly.— D. Paste, Zinc-Dermatol, Unna's. Dermatol av.oz. 1 Zinc oxid av.oz. 1 Wool fat, hydrous av.oz. 2 Linseed oil, raw sufficient Rub the dermatol and zinc oxid to- gether with the oil to a paste and add the wool fat.— D. Paste, Zinc-Sulfur, Unna's. Zinc oxid parts 3 Precipitated sulfur parts 2 Silicic acid (silica) part 1 Benzoinated lard parts 14 Thoroughly levigate the zinc oxid with a small portion of the benzoinated lard, the silica with another, and the sulfur with a third portion. Mix the three portions until a uniformly smooth mix- ture results and thoroughly incorporate the remainder of the lard. — N. F. Paste, Zoll's Pink. This is said to be prepared as fol- lows : Sandalwood oil part 1 Oil of copaiba parts 3 Oil of turpentine parts 4 Sugar parts 8 Acacia parts 8 Mix and rub up together. This is used in some hospitals. Pastilles, Glyco-Gelatin. The London Throat Hospital uses a form of troche called glyco-gelatin pas- tilles. The vehicle for these is to be prepared as follows: Gelatin, pure av.oz. 1 Glycerin av.oz. 2*4 Oramje flower water av.oz. 2^4 Solution of carmine, sufficient to color as desired. The gelatin is to be soaked in the water for 2 hours, the mixture is to be heated on the water bath until the gela- tin is dissolved, the glycerin is to be added, and finally the carmine solution. The medication of the pastilles is ac- complished by warming a sufficient quantitv of the above glyco-gelatin on a water bath, then incorporating the medicament, previously rubbed to a thick paste with glycerin if it be a solid, stirring till somewhat cool, and making into square or round or pastilles, pref- erably the latter, which may be formed in a suitable mold, which latter should be slightly oiled before used. The medicament, if it be a solid, must be rubbed to an impalpable powder with the glvcerin before incorporating with the vehicle. Most of the medicaments are in solid form and hence this method of incorporation applies in most in- stances. Sometimes the medicament may or should be otherwise incorporated. Carbolic acid may be dissolved in a small amount of glycerin by the aid of a gentle heat. Water-soluble substances like ammonium chlorid may be tritura- ted with glycerin or they may be dis- solved in the water used to make the glyco-gelatin vehicle. Substances like menthol may be incorporated by dissolv- ing in as small amount of alcohol and adding this solution to the melted ve- hicle. Other flavors may be used in the glyco-gelatin vehicle besides orange flower water, such as rose or tolu water. The carmine coloring may be omitted if desired. Most of the troches (see Troches) may be made into glyco-gelatin pastilles if desired. PHARMACEUTICAL PREPARATIONS. Pellets, Homeopathic. See Medications, Homeopathic. Pencils, Cocaine, 5 per cent. Cocaine hydrochloric! part I Tragacanth part j Starch parts ? Dextrin parts 7 S^r • parts 4 Distilled water, to make a firm plas- tic mass. All solids should be in fine powder — N. F. See Pencils, Paste, for method of preparing these pencils. 1 av.ounce of this material makes about 15 pencils. Pencils, Iodoform. (Bacilli Iodoform.) Iodoform, fine powder parts 10 Cocoa butter parts 9 Castor oil p ar |- z Mix all in a gently warmed mortar, and when the mass has partially cooled, suck it into glass tubes having a lumen of % inch, place these in cold water, push the mass out when cold, and cut it into pencils about 2^ inches long.— Germ. Form. Jhe pencils may also be prepared by mixing the cocoa butter in a grated con- dition with the oil and iodoform, add- ing a little more oil if necessary, until a suitable mass is obtained, then rolling out on a pillboard or tile like a pill .mass and cutting into required lengths. 289 Pencils, Menthol. (Migraine Pen- cils—Stilus Mentholi.) These may be prepared by carefully melting pure menthol and pouring into tin molds having about the form of an ordinary thimble, in which it is allowed to crystallize at a low temperature, usu- ally by placing in an ice chest or other cold place for 12 hours. The menthol cone is removed from the molds, at- tached to a handle and preserved in a convenient form for use. A good cone should be made only of pure menthol, as even so small a quantity as 2 per cent, of thymol, which addition has been rec- ommended, will render them greasy. The cone may be attached to the holder with some liquid glue or solution of glue in hot water. Pencils, Paste. (Medicated Pencils- Stilus dilubilis— Pasten Stiften.) These pencils are for the direct ap- plication of medicinal agents to the skin, suggested by Dr. Unna, and used in modern dermatologic practice. The me- dicinal agent is incorporated with a paste consisting of starch, dextrin, trag- acanth and sugar [all solids used should be in very fine powder] with enough distilled water to form a plastic mass. This^ is rolled into cylinders of about 1/5 inch diameter which are cut into sections 2 inches long, dried on parch- ment paper at the room temperature and wrapped in tin-foil.— N. F. Pencils of cocaine and salicylic acid are recognized by the N. F. Other medications used are ichthyol, pyrogal- lol, mercuric chlorid, zinc oxid, etc. Pencils, Salicylic Acid, 10 per cent. Salicylic acid parts 2 Tragacanth part I Starch parts 6 Dextrin parts 7 Sugar parts . Distilled water, to make a firm plas- tic mass. All solids should be in fine powder. — N. F. See Pencils, Paste, for method of preparing these pencils. 1 av.ounce of this material makes 12 or 13 pencils. Pepsin, Aromatic. Saccharated pepsin g r . 480 Aromatic fluid extract m. 30 Tartaric acid gr _ g Sodium chlorid gr. 8 Mix the ingredients by trituration, dry' the product by exposure to warm air, and keep it in well-stoppered bottles. Pepsin, Saccharated. Pepsin (1:3000) avoz 1 Sugar of milk, recently dried, in No. 30 powder av.oz. 9 Triturate the pepsin with the sugar of milk to a fine, uniform powder. Keep the product in well-stoppered 890 STANDARD FORMULARY OF bottles.— N. F. and U. S. P. 1890. A weaker pepsin than a i to 3000 may be employed for this mixture if pro- portionately more of it be used and correspondingly less milk sugar. Petrolatum. (Soft Paraffin— Petrole- um Ointment.) See Paraffins. Petrolatum, Saponated, Liquid. (Liquid Petrox.) Liquid petrolatum, U. S. P.. parts 5 Oleic acid, U. S. P parts 3 Oil lavender part 1/5 Stronger ammonia water part Yz Alcohol part \y 2 Mix them. Other N. F. preparations of petrox- olin are petrox. betanaphthol, 9 to 1 ; cade, 3 to 1 ; chloroform camph., 2 to 1 each ;"creosote, 4 to 1 with % part oleic acid; eucalyptol, 4 to 1 ; guaiacol, 4 to 1 with Y^ part oleic acid; mercury, 2 to 1 with lanolin and oleic acid ; iodine, 10% iodine ; iodine, dilute, 5% iodine ; iodo- form 3 parts, with acetone 20 parts, oleic acid 10 parts, eucalyptol, 3 parts ; men- thol, 3 parts ; oil wintergreen, 20 parts ; phenol, 5 parts ; camphorated phenol, camphor 37 parts, phenol, 12 parts; tar, 25 parts ; sulphur, 3 parts with linseed oil 37 parts and oleic acid 30 parts ; Ven- ice turpentine, 20 parts. Petrolatum, Saponated, Solid. (Solid Petrox.) Petrolatum, yellow, U. S. P.. parts 4 Oleic acid, U. S. P parts 2 Spirit of ammonia, U. S. P. .part 1 Melt the petrolatum on a water bath, add the acid, and stir the mixture until it has cooled almost to the point of con- gealing, then add the spirit of ammonia while stirring, and continue to stir until th<> mixture is cold.— N. F. Pills. (Pilulaj.) The pills enumerated here are made according to the methods usually ap- proved. The mass for pills of the U. S. P. and nearly all other pharmacopeias is usually divided into the appropriate number or size, while in the case of the Brit. Pharm. it is usually allowed to remain as such, the same to be divided as re- quired. The "pills" of the Brit. Pharm. are, therefore, strictly speaking, "mass- es." The dose of these "pills" is stated by this work. In looking up Pills, com- pare same with Macses. Pills, Abernethy's. See Abernethy's Remedies. Pills of Aconite, Compound. Each pill should contain — Extract of aconite leaves gr. Yz Extract of stramonium leaves.gr. 1/15 Quinine valerianate gr. l /z — Eclectic. Pills, Aloes. Each pill should contain — Aloes, purified gr. 2 Soap, castile gr. 2 Each of these is to be in fine powder, and the mixture is to be massed with water.— U. S. P. The Brit. Pharm. recognizes Pill of Barbadoes Aloes, which is made from 2 av. ounces of barbadoes aloes, 1 of castile soap, 1 or sufficient of confection of rose, and 1 fluidram of oil of cara- way. The dose is 4 to 8 grains. The same work also recognizes a Pill of Socotrine Aloes, which is made like the preceding except that socotrine aloes is used instead of the barbadoes, and oil of nutmeg instead of oil of caraway. Dose, 4 to 8 grains. Pills of Aloes and Asafetida. Each pill should contain — Aloes, purified gr. V/s Asafetida gr. \Ys Soap, castile gr. 1*/$ Beat with sufficient water to form a mass. — N. F. Appendix and U. S. P. 1890. Only select tears of asafetida should be used for the above. Pill of aloes of asafetida, Brit. Pharm., PHARMACEUTICAL PREPARATIONS. 240 120 I20 60 DO 60 30 pills is made from 1 av.ounce each of soco- trine aloes, asafetida, and castile soap and 1 aviounce or sufficient of confec- tion of rose. Dose, 4 to 8 grains. Pills of Aloes, Compound. (Antidvs- peptic Pills.) Aloes g r# - Gamboge !!'. !.'gr. Castile soap g T [ Extract of boneset .'.'.' .'gr. Extract of mandrake gr. Extract of ginseng gr.' Capsicum gr Lobelia seed er' Oil of clove '.'/.m.' 1 Make a mass and divide into weighing 4 grains each.— Eclectic. Another formula is also used, as fol lows : Aloes, socotrine gr. 240 Extract of gentian .gr. 240 Castile soap g r _ I2 o Colocynth g r _" I20 Gamboge [] gr [ I20 Oil of clove m. I5 Divide like the preceding. This is said to be the formula origi- nally employed. Pills of Aloes and Iron. (Ferrated Aloetic Pills.) Each pill should contain — Aloes, purified g r> x Ferrous sulfate, dried .'.'.'gr.' 1 Aromatic powder g r . 1 Confection of rose, enough to make a mass. — N. F. Pill of aloes and iron, Brit. Pharm., is made from 1 av.ounce of dried fer- rous sulfate, 2 of barbadoes aloes, 3 of compound powder of cinnamon, and 3 or sufficient of syrup of glucose. Dose, 4 to 8 grains. The Ferrated Aloetic Pills, Germ. Pharm., are made from equal parts by weight of dried ferrous sulfate and aloes, "massed" with spirit of soap, and divided into i^-grain pills. Pills of Aloes and Mastic. (Dinner Pills— Lady Webster's Dinner Pills—Lady Hesketh's Dinner Pills— Crespigny's Pills.) Each pill should contain— Aloes, purified gr. Mastic < ]g V [ Red rose petals, fine powder... gr. 291 to form a (Rufus's Beat with diluted alcohol mass. — N. F. Pills of Aloes and Myrrh. Pills.) Each pill should contain — Aloes, purified ffr Myrrh,. .:.::::£? Aromatic powder g r# 3/- Make into a mass with simple syrup. — N. F. Pill of aloes and myrrh, Brit. Pharm., is made from 2 av.ounces of socotrine aloes, 1 of myrrh, and 2^ or sufficient of syrup of glucose. Dose, 4 to 8 grains. Pills of Aloes and Podophyllum, Compound. (Janeway's Pills- Compound Pills of Podophyllin.) Each pill should contain— Aloes, purified g r . 1 Resin of podophyllum. .'. .' .' ' ' [ .'gr.' y 2 Extract of belladonna leaves, .gr. y A Extract of nux vomica gr ]/ A — N. F. Pills of Aloin, Compound. Each pill should contain— Aloin gr. x/ of podophyllum g r . J 2 3/5 Resin Extract of belladonna leaves — N. F. Pills of Aloin, Strychnine and Bella- donna. Each pill should contain— Aloin gr# j/ 5 Strychnine (alkaloid) gr ! 1/120 Extract of belladonna leaves..gr." % — N. F. These pills are also prepared ' with double the amount of strychnine. It is recommended that the stronger pills be dispensed only when specially demanded. However, the pill usually dispensed, the so-called No. 1, does contain 1/60 gr. of strychnine. Aloin, strychnine and extract of belladonna are also combined in proportions other fchan those given above. Pills of Aloin, Strychnine and Bella- donna, Compound. Each pill should contain— Aloin g n j/r Strychnine (alkaloid) ...'].' .'gr.' 1/120 Extract of belladonna leaves. .gr.' % Extract of cascara sagrada..gr l /> — N. F. These pills are also prepared with 292 STANDARD FOR MULARY OF The .av.oz. . . .av.oz. . . .av.oz. . . .av.oz. ....fl.dr. 6 i Va Va i double the amount of strychnine N. F. recommends that the stronger pill be dispensed only when specially de- manded. However, the commercial al- most always does contain 1/60 gr. of strychnine. Pills, Anderson's Scot's. Formula of the Philadelphia College of Pharmacy : Each pill should contain— Barbadoes aloes . . Soap Colocynth Gamboge Oil of anise Water sufficient Mix the aloes, colocvnth and gamboge, previously reduced to very fine powder, add the soap and sufficient water to form a mass, and divide into 3-grain pills. The pills made by manufacturing houses each contain — Aloes, purified g r - 1 3/5 Colocynth S r - *l}\ Gamboge g[- */**> 1/30 gr. gr. Soap § r - Oil of anise g r - Pills, Anti-Canker. (Compound Iron Pills.) This formula appears in some formu- laries and is credited to Thomsonian practice : Each pill should contain— Iron subcarbonate gr. 2 V 2 Extract of conium gr. 2/2 See also Pills No. 3- Pills, Anti-Catarrhal, Andrews'. (Anti-Grippe or Yellow Pills.) Each pill should contain— Quinine salicylate gr. 1 Arsenous acid gr. T / I2 5 Ext. of belladonna leaves. . .gr. 1/33 Pills, Anti-Constipation, Carson's. Each pill should contain — Extract of cascara sagrada gr. 1 Extract of rhubarb gr. 1 Extract of nux vomica gr. V\ Aloin gr- l A Pills, Anti-Constipation, Goss\ Each pill should contain— Resin of podophyllum gr. J A Extract of colocynth gr. V\ Extract of butternut bark gr. T /2 Extract of nux vomica gr. l A Extract of henbane g r - A Extract of gentian gr. A Extract of cascara sagrada gr. A Apocynum cannab., powder gr. A Pills, Antidyspeptic. Each pill should contain— Strychnine (alkaloid) gr. 1/40 Ipecac • g r - ^ Extract of belladonna leaves.gr. 1/10 Mass of mercury g r - 2 Comp. ext. of colocynth. .. .gr 2 — N. F. See also Pills, Carminative. Pills, Antineuralgic. (Neuralgia Pills.) I. Gross': Each pill should contain— Quinine sulfate gr. 2 Morphine sulfate gr. 1/20 Strychnine (alkaloid) gr. 1/30 Arsenous acid g r - 1/ 20 Extract of aconite leaves gr. 1/2 When Antineuralgic Pills, or Neural- gia Pills, without other specification, are prescribed, it is recommended that the above preparation be dispensed. Some- times the morphine is omitted. II. Brown-Sequard's : Each pill should contain— Extract of henbane gr. 2/3 Extract of conium gr. 2/3 Extract of ignatia gr. 1/2 Extract of opium gr. 1/2 Extract of aconite leaves. gr. 1/3 Extract of Indian cannabis gr. 1/4 Extract of stramonium gr. 1/5 Extract of belladonna leaves. . .gr. 1/0 Pills, Antimony, Compound. (Plum- mer's Alterative Pills— Compound Calomel Pills— Compound Pills of Mercurous Chlorid.) Each pill should contain— Sulfurated antimony (ker- mes mineral) g r - 3/5 Calomel g r - 3/5 Guaiac resin gr. 1 *'S Castor oil sufficient _ Triturate the powders together until well mixed, then mass with the oil which should be very gradually added.— N. F. and U. S. P. 1890. The U. S. P. 1880 directed mucilage of tragacanth for massing the powders. Plummer's Pill, Brit. Pharm., is made from 1 av. ounce each of calomel and PHARMACEUTICAL PREPARATIONS sulfurated antimony, 2 of guaiac resin, 180 grains of castor oil, and 1 fluidram or sufficient alcohol. Dose, 4 to 8 grains. Pills, Antiperiodic. (Warburg's Pills.) 6 I. With aloes: Each pill should- contain— Extract of aloes gr T * hub f rb ••••• Wgn 1/2 Angelica seed 293 Elecampane gr. 1/2 1/4 /4 Pills of Asafetida, Compound. Each pill should contain Asafetida, Opium, Ammonium carbonate, each. ..gr. 4/5 Mix the opium and asafetida together by the aid of a gentle heat and, while soft, incorporate the bonate.— Eclectic. ammonium car- /8 1/8 1/8 1./8 1/8 Saffron " " r ^ e " nei ..wwww.gr: i/ 4 ^°? ry gr. 1/8 Cubeb r_ Myrrh wwwwfr; W hite agaric £ r Camphor Wgr Quinine sulfate gr " T 2/c Extract of gentian... sufficient Reduce the drugs to a fine, uniform powder, and make this into pill form by means of extract of gentian.— N. F. II. Without aloes : Prepare in the same manner as di- rected in the previous formula, but omit the extract of aloes. _N. F. These pills have been introduced for the purpose of facilitating the adminis- tration of Warburg's Tincture in a solid form. When Warburg's Pills, or Pills of Warburg's Tincture are prescribed, without further specification, those con- taining aloes should be dispensed. Those Without aloes should be furnished only when they are expressly demanded. Each Warburg's pill represents about 1 fluidram of Warburg's Tincture, with or without aloes, respectively (see Tinc- ture, Antiperiodic). Pills, Arsenic, Hebra's. Each pill should contain Arsenous acid gr 2 / 2 r Extract of licorice, powder.'! .'gr' z/a. licorice root, powder sr %/l Mucilage of acacia sufficient Roll in lycopodium.— D. Pills, Asafetida. Each pill should contain Asafetida gr . Soap, castile, fine powder* . W 'g r * 1 Make a mass with water.— U. S. P The asafetida should be in select tears. Pills, Asiatic. Each pill should contain Arsenous acid gn l/l6 -Black pepper gr x / 2 Mucilage of acacia, to form 'a mass. — Eclectic. Pills of Black Colosh, Compound. (Compound Pills of Cimicifuga.) Each pill should contain Extract of black cohosh. . gr 1 Extract of sculcap gr " T Quinine valerianate Wgr. y 2 — Eclectic. Pills of Camphor, Compound. (Chol- era Pills.) Each pill should contain Camphor ffr Opium .WW" Jr Kino '. . .. Capsicum gr. 1 gr. 1 Confection of rose, .".".".".'.'.'sufficient — Eclectic. These pills are given in Asiatic chol- era, one pill being given after each dis- charge from bowels, or oftener, if the urgency of the case demands it. Pills, Carminative. (Fothergiir tidyspeptic Pills.) Each pill should contain Strychnine sulfate Ipecac Black pepper Extract of gentian '.'" ar s An- gr. 1/20 gr. 2/3 1 1/2 gr. 1 What are called Modified Carminative Pills, Modified Fothergill's Antidyspep- tic Pills, or Fothergill's Tonic and Car- minative Pills are each to contain Strychnine sulfate g ,. , /f Black pepper .....WW" Oil of clove Extract of gentian.!.. •gr • gr. 1 7 gr. 1 1/4 20 294 STANDARD FORMULARY OF Pills, Cascara Cathartic, Hinckle's. (Hinckle's Comp'd Cascara Pills — Cascarin Comp. Pills.) Each pill should contain Cascarin § r - ]/+ Aloin g f - l/ A Podophylhn S r Extract of belladonna gr 1/6 1/8 Strychnine fj \^ Gingerine S r - l/8 Sometimes l £ gr. of extract of cas- cara is substituted for the cascarin. Gin- gerine is oleoresin of ginger. Pills, Catarrh, Hager's. (Pilul® An- tiphlogistic® Hageri— Conchmin Pills.) Each pill should contain Chinidine sulfate gr. 3/4 Gentian root • g r - 5/» Tragacanth .: S r - 3-/ 2° Althea § r - \% n Hydrochloric acid . . .gr. 3/1° Roll in powdered cassia cinnamon — Hager's Manual. The formula as given Hager's Praxis is as follows : Each pill should contain Chinidine sulfate gr. 3/4 Tragacanth g r - K 2 Althea § r - /4 Gentian root g r - x/ 4 Red saunders g r - l / / \ 2 . Glycerin S r - 9 ^ Hydrochloric acid gr. 9/1° One American manufacturer follows the latter in its essential constituents, but using V& gr. each of quinidine and cinchonidine sulfates for the chinidine, another uses V% gr. each quinine and cinchonidine sulfates for the same. Pills, Cathartic, Compound. (Anti- bilious Pills.) I. Each pill should contain Comp. ext. of colocynth gr. 1/4 Calomel S r - * Resin of jalap gj- (j Ma£e°the mass' with diluted alcohol. The U. S. P. 1890 directed V2 gr. of extract of jalap instead of the resin. II. Each pill should contain Extract of culver's root gr. 3/5 Gamboge § r - 3'5 Scammony g f - 3/5 Podophyllin gr- 3/io Castile soap gr- 3/1° Another eclectic formula is 1 gr. each of extract of henbane and extract of culver's root and K g r - of podophyllin for each pill. —Eclectic. Pills, Cathartic, Vegetable. ("Im- proved" Vegetable Cathartic Pills.) Each pill should contain Comp. ext. of colocynth gr. I Extract of henbane gr. Vj Extract of leptandra • • gr. A Resin of jalap g r - /} Podophyllin g r - V* Oil of peppermint ■ • • m. A Mix the compound extract intimately with the resin of jalap, extract of lep- tandra, and podonhyllin, and then add the oil. Rub the extract of henbane with enough diluted alcohol to render it plastic, incorporate it with the mix- ture first prepared, then add diluted al- cohol to make a mass.— N. F. Pill Coating. The N. F. has this to say about pills and pill coating :— Pills, in their simplest form, are prepared as required and dis- pensed with enough dusting powder to prevent them from adhering while still moist; but if they are prepared for stock, or if it is desirable to mask their taste, or for other reasons, they may be coated with some suitable substance that will readily dissolve or disintegrate in the juices of the stomach (sugar, gela- tin, chocolate, tolu, silver). In some cases, however, it is desirable to coat the pills with a material which, while insoluble in the acid contents of the stomach (salol, keratin), dissolves read- ily in the alkaline fluids of the intes- tines. I. Gelatin Coating: The pills, freed from dusting powder may be dipped in a warm solution of gelatin? th7 excess removed, and allowed to dry. In extemporaneous pharmacy, it may be convenient to roll the pills into cylindrical shape and insert them into gelatin capsules of suitable size, so PHARMACEUTICAL PREPARATIONS. 295 as to completely fill them, observing that here also the dusting powder is com- pletely removed. II. Sugar Coating: The pills, freed from dusting powder, may be quickly rolled on a filter paper saturated with mucilage of acacia, until uniformly but superficially moist, then immediately transferred to a porcelain capsule containing a mixture of 4 parts of powdered milk sugar and 1 part of powdered acacia, and rapidly rotated un- til covered with a firm, white coating. III. Cocoa Coating: Moisten the pills with mucilage as in the preceding, then immediately shake with powdered cocoa until well coated, transfer to a clean warmed porcelain capsule, and rotate rapidly until a smooth coating is produced. IV. Tolu Coating: The pills, freed from dusting powder, may be dropped into the lid of a por- celain ointment jar (or a porcelain cap- sule) into which a thin layer of ethereal tincture of tolu has previously been placed and rotated until coated with the tincture. They are then turned into an- other lid (or capsule) of the same kind and size and rotated for a few moments to remove the excess of tincture, and while the pills are still shining, but not too -moist, they are transferred to and rotated until dry in a third lid (or cap- sule), previously coated with a very thin layer of oil, which has been applied by merely the tips of the fingers. A second or third coating may be applied in the same manner, if necessary. V. Silver Coating: The pills, preferably coated with tolu (as described under IV), if moist, are dropped into the lid of a porcelain oint- ment jar, into which a very thin layer of a mixture composed of equal parts of alcohol, simnle syrup, mucilage of acacia and water has been placed, and they are rotated until they have acquired a thin coat of this mixture. They are then dropped into a one-pound ointment jar, containing the requisite quantity of sil- ver-foil (determined by experience), and the jar is rapidly rotated until the pills are thoroughly coated. This coat- ing may be brightened by transferring the pills to a second jar, containing a few leaves of silver-foil and shaking for some time until thoroughly polished. VI. Keratin Coating: The pills, which should not be massed with an aqueous excipient, may be dipped into melted cocoa butter, rolled in finely powdered charcoal, then sprin- kled with a suitable quantity of solution of keratin, and rotated until dry. The sprinkling and drying are repeated sev- eral times until a sufficiently thick coat- ing of keratin is obtained. VII. Salol Coating: The pills, carefully freed from dust- ing powder, are dropped into a capsule containing enough salol (approximately 1 gr. for every 3-gr. pill), previously melted by the heat of a water bath and allowed to cool so that by passing the hand along the bottom of the dish there is scarcely any warmth felt, and the capsule is then rotated until the pills are coated and the salol has congealed. This process is repeated twice, each time reducing the salol about one-half. Finally a finishing coat is applied by using only enough salol to coat the dish when melted ; the dish being now kept quite warm (almost hot), the pills ro- tated quite rapidly until they are quite shiny, then turned into a cool dish, and the rotation continued until the pills are quite cool. Pills of Colocynth, Compound. (Pilu- les Cocciee — Cochia Pills.) Each pill should contain Extract of colocynth gr. 1-6 Purified aloes gr. 2 Resin of scammony gr. 2 Oil of clove m. 1/4 — N. F. The Pilula Colocynthidis Composita of the Brit. Pharm., for which the above is an equivalent, is prepared with colo- cynth pulp, and contains potassium sul- 296 STANDARD FORM ULARY OF fate, which was originally added as an aid to reduce the ingredients to powder. With the use of extract of colocynth, this becomes unnecessary. The directions of the Brit. Pharm. are to triturate 2 fluidrams of oil of clove with Ya av.ounce of potassium sulfate, in very fine powder, add 1 av.ounce of colocynth pulp, and 2 av.ounces each of barbadoes aloes and resin of scammony, mix well, and incorporate enough water to make a mass. Dose, 4 to 8 grains. Pills of Colocynth and Henbane. Each pill should contain Extract of colocynth gr. 1/10 Extract of henbane gr. 1 « 2 Purified aloes gr. I 1/2 Resin of scammony gr. n/2 Oil of clove rn. 1/6 The Pilula Colocynthidis et Hyoscy- ami of the Brit. Pharm. is directed to be made by mixing 2 parts of compound pill of colocynth (see Pill of Colocynth, Compound) with 1 part of extract of henbane, and is directed to be kept as a pill-mass, to be made into pills of such weight as may be directed.— N. F. Pills of Colocynth and Podophyllum. Each pill should contain Comp. ext. of colocynth gr. 2 x /2 Resin of podophyllum V§r. /4 — JN. r. gr. 1 .gr. 1 / -gr. V2 .gr. V2 Pills, Cook's. Each pill should contain Rhubarb Aloes Calomel Soap Pills of Copaiba. Each pill should contain Copaiba balsam S r - 2 White wax « ^f —Eclectic. Pills of Copaiba, Compound. Mass of copaiba gr. 60 Myrrh * r - °° Oleoresin of cubeb . g r - 3° Extract of nux vomica gr. 15 Resin of podophyllum gr. 9 Divide into 3-gr. pills.— Eclectic. Pills, Creosote. Creosote is very difficult to incorpo- rate into pills unless wax is used, an objectionable substance because not readily disintegrated in the alimentary canal. Various methods have been sug- gested to "mass" creosote, but all more or less satisfactory. The following method works quite well. Make a paste or jelly of Gelatin P ar ts n Sugar Parts 5 Water P af ts 24 Dissolve the gelatin and sugar in the water by the aid of a gentle heat. This mixture is to be kept on hand and used for making creosote pills. One grain of the jelly will mass one minim of creosote. To make 20 one-minim creosote pills, weigh 20 grains of the jelly, put into a previously warmed mortar so as to liquefy the paste, add the creosote, mix well, and bring to proper pill-mass consistence by adding about 10 grains of powdered extract of licorice and 20 of powdered licorice root. These pills will be of about the size of 2-grain quinine pills. Larger amounts of creosote, of course, acquire a larger proportion of the other sub- stances. The creosote pills of the Germ. Pharm. are directed to be made as fol- lows: Creosote, beechwood gr. 100 Licorice root, fine powder... gr. 190 Glycerin § r - I0 Mix the creosote and licorice root in- timately, add the glycerin, make a pill mass, and dhide into pills weighing 2 y A gr . (0.15 g.) ; dust with powdered cinnamon. Pills of Dandelion, Compound. Extract of dandelion gr. 60 Bloodroot S r - <*> Podophyllin S r - ™ Oil of spearmint m - Make into 50 pills— Eclectic. These pills are laxative and diuretic, useful in jaundice, kidney and liver dis- eases, etc., the dose being I to 2 pills 3 times a day. Pills, Dinner. I. When "Dinner Pills," under this or some other equivalent name, are pre- PHARMACEUTICAL PREPARATIONS. 297 scribed without further specification, it is recommended that the Pills of Aloes and Mastic, also called Lady Webster's Dinner Pills, be dispensed. Of other combinations, bearing simi- lar names, or used for similar purposes, the following appear to be those most commonly in use : II. Chapman's Dinner Pill: Each pill should contain Purified aloes gr. i 1/2 Mastic gr. 1 1/2 Ipecac gr. 1 Oil of fennel about m. 1/4 The commercial pill usually contains 1 gr. of aloes, mastic and rhubarb. III. Cole's Dinner Pill: Each pill should contain Purified aloes gr. 1 1/5 Mass of mercury gr. 1 1/5 Jalap gr. 1 1/5 Tartai emetic gr. 1/50 IV. Hall's Dinner Pill: Each pill should contain Purified aloes gr. 1 Extract of licorice gr. 1 Soap, powder gr. 1 Molasses gr. 1 — N. F. Pills, Emetic. Extract of peach leaves, pop- lar or butternut bark oz. 1 Capsicum, powder . . . .teaspoonful 1 Lobelia seed, powder oz. y 2 Ladies' slipper, powder teaspoonfuls 2 Oil of pennyroyal, spearmint or peppermint a few drops Make a mass and divide into pills (number not stated). — Thomsonian (from the Materia Medica). Pills of Galbanum, Comp'd. (Comp'd Pills of Asafetida.) Each pill should contain Galbanum gr. V/ 2 Myrrh gr. i l / 2 Asafetida gr. y 2 Simple syrup sufficient rr-U. S. P. 1880. Compound Pill of Galbanum, Brit. Pharm., is made from 2 av.ounces each of galbanum, myrrh, and asafetida, and I av.ounce or sufficient syrup of glucose. The gum resins should be used whole ; all should be heated together on a wa- ter bath, stirring until a uniform mass is produced. Dose, 4' to 8 grains. Pills of Gamboge, Compound. I. Each pill should contain Gamboge gr. I Scammony gr. 1 Elaterium gr. 1/6 Croton oil m. 2/3 Extract of henbane sufficient — Eclectic. This is the formula as it is given. II. Gamboge av.oz. 1 Barbadoes aloes av.oz. 1 Comp. powder of cinnamon. av.oz. 1 Castile soap av.oz. 2 Syrup of glucose.av.oz. 1 or sufficient Dose, 4 to 8 grains. — Brit. Form. Pills of Nitroglycerin. (Pills of Glonoin.) Each pill should contain Spirit of glonoin gr. 1 Althea gr. 1 Confection of rose sufficient Mix the spirit intimately with the powdered althea, expose the mixture for a short time to, the air, so that the alco- hol may evaporate, then make a pill mass by means of confection of rose. Each pill contains 1/100 grain of glonoin (nitroglycerin). — N. F. Pills of Henbane, Compound. Extract of henbane leaves. . . .gr. 60 Extract of valerian gr. 60 Extract of aconite leaves gr. 30 Quinine sulfate gr. 30 Divide into 3-gr. pills. — Eclectic. These pills are useful in neuralgia, rheumatism, dysmenorrhea, chorea, etc., giving one every 2, 3 or 4 hours. Pills, Hooper's Female. (Hooper's Pills.) Formula adopted by the Philadelphia College of Pharmacy: Barbadoes aloes av.oz. 8 Ferrous sulfate, dried av.oz. 2 . . gr. 90 Or crystal ferrous sulfate. av.oz. 4 Extract of black hellebore. av.oz. 2 Myrrh av.oz. 2 Castile soap av.oz. 2 Canella av.oz. 1 Ginger av.oz. 1 Water sufficient Divide into 2^-grain pills. ^98 STANDARD FORMULARY OF - manufacturing The pills made by houses each contain Aloes, purified g r - T Ferrous sulfate, dried gr. >J Extract of black hellebore. .. .gr. V\ Myrrh S r - H Soap S r - Y/ Ginger g r - $ Canella g r - n Pills, Imperial. (Kaiser Pillen.) Various formulas are used for Kaiser Pillen. These pills are purgative; the following may be used: Resin of jalap gr. 30 Resin of scammony. gr. 3° Gamboge § r - 3Q Aloes >---g r - 30 Extract of colocynth gr. o Soap g r - x § Gentian root g r - 3© Water, enough to make pills 100 Sometimes calomel is added. — H. Pill, Iodin. Each pill should contain Iodin g^ 1/2 Morphine sulfate gr. 1/10 Burnt sponge gr. I — Eclectic. Pill of Ipecac with Squill. Comp. powder of ipecac — av.oz. 3 Squill av.oz. 1 Ammoniac a Yi°?- T Syrup of glucose sufficient This contains about .5 per cent, of opium. Dose, 4 to 8 grains.— Brit. Pharm. Pills of Iron (Ferrous) Carbonate. (Blaud's Pills— Ferruginous Pills —Chalybeate Pills— Iron Pills.) I. Ferrous sulfate, granulated, .gr. 250 Potassium carbonate gr. 125 Sugar gr- 6° Tragacanth, fine powder. .. .gr. 15 Althea, No. 60 powder gr. ^ 15 Glycerin, water, each sufficient Rub the potassium carbonate in a mor- tar with a sufficient quantity (about 10 drops each) of glycerin and water, then with the ferrous sulfate and sugar, pre- viously rubbed together to a uniform powder, and rub the mass thoroughly until it assumes a greenish color. When the reaction has terminated, incorpo- rate the tragacanth and althea, and, if necessary, add a little more water so as to obtain a mass of pilular consistence. Divide into 100 pills.— U. S. P. These pills should be freshly pre- pared when wanted. Each pill contains about 1 grain of ferrous carbonate. These pills were recognized by the N. F., 1st edition, but the proportions were somewhat different; there was somewhat more potassium carbonate, somewhat less sugar, and no althea. Sometimes so-called 3-grain Blaud's pills (Pilulse Blaudii minores) are pre- scribed or demanded. These may be prepared by using the quantities given in the above formula but dividing the mass into 168 pills. To obtain pills of ferrous carbonate, the mass of iron carbonate or Vallet's mass may be used if desired, although exactly the same composition is not ob- tained. The commercial Bland's pills, regular size or 5-grain, are always stated to be made with 2 l / 2 grains each of ferrous sulfate and potassium carbonate. The U. S. P. pill is made with 2 l / 2 grains of ferrous sulfate and just sufficient po- tassium carbonate to convert this into ferrous carbonate, so that the latter is preferable. Similarly the commercial 3-grain pill is stated to be made with i]/ 2 grains each of ferrous sulfate and potassium carbonate, but the U. S. P. mixture made into 168, instead of 100, pills, should be preferred. II. The Pilula Ferri or Iron Pill of the Brit. Pharm. is prepared as fol- lows : Ferrous sulfate, pure, dried, .gr. 150 Sodium carbonate, pure, dried gr. 95 Acacia, powder gr. 50 Tragacanth, powder gr. 15 Simple syrup gr. 15° Glvcerin gr. . 10 Distilled water . . .gr. 20 or sufficient To the syrup, glycerin and water, pre- viously mixed, add the ferrous sulfate, mix, quickly add the sodium carbonate, mix thoroughly, set aside for 15 min- PHARMACEUTICAL PREPARATIONS. 299 utes, or until the reaction is complete, add the two gums, and incorporate thoroughly. Dose, 5 to 15 grains. If divided into 5-grain pills, each pill will contain about 1 grain of ferrous carbonate. III. Ferrous sulfate, pure, crys- tal r. ..gr. 250 Potassium carbonate, purc.gr. 150 Sugar, powder gr. 50 Tragacanth, powder gr. 17 Glycerin, distilled water, each.m. 11 Reduce the ferrous sulfate to fine powder, add the sugar and tragacanth, and mix intimately. Powder the car- bonate finely in another mortar, and thoroughly incorporate the glycerin and water. Transfer this mixture to the mortar containing the iron, beat the whole thoroughly until the mass be- comes green and assumes a soft pilular consistence, and divide into 100 pills. — Brit. Form. (2nd ed.). IV. Ferrous sulfate, dried gr. 135 Potassium carbonate, finely powdered gr. 105 Sugar, powder gr. 45 Marshmallow root, powder, .gr. 20 Magnesia, calcined gr. 10 Glycerin. . .sufficient or about gr 60 Mix the solids intimately, add enough glycerin to make a suitable pill mass and divide into pills weighing 4 grains (0.25 g.) ; dust with lycopodium. — Germ. Pharm. V. The following is said to be the original formula of Blaud : Ferrous sulfate, pure dried.. gr. 384 Potassium carbonate, pure, dried gr. 384 Acacia gr. 64 Simple syrup gr. 192 Water gr. 384 Dissolve the acacia in the water, in a porcelain capsule, on a water bath, add the syrup and ferrous sulfate, stir for some moments to make the mixture ho- mogeneous, add the potassium carbon- ate, constantly stirring with an iron spatula, and continue stirring until the mass has acquired a pilular consistence rather more hard than soft. Withdraw from the source of heat and divide the mass into 100 pills, which must be dried in the stove, and then silvered. Put into bottles and cork well. Each pill weighs about 6 grains. Pills of Iron, Compound. (Griffith's Pills.) I. Each pill should contain Myrrh gr. i l / 2 Sodium carbonate, crystal gr. Y\ Ferrous sulfate gr. Y\ Simple syrup sufficient II. Eclectic Compound Pills of Iron (or Emmenagogue Pills) are as fol- lows : Each pill should contain Mass of iron carbonate gr. 2 Gum turpentine gr. 1 Resin of podophyllum gr. y 2 Pills of Iron Ferrocyanid, Compound. Each pill should contain Iron ferrocyanid, Quinine sulfate, Extract of black cohosh, each. .gr. 1 — Eclectic. These pills are tonic, alterative and antiperiodic and are used in intermit- tent fever, chorea, epilepsy, etc. Pills of Iron (Ferrous) Iodid. (Blancard's Pills.) Reduced iron gr. 60 Iodin gr. 75 Licorice root, No. 60 powd..gr. 60 Sugar, fine powder gr. 60 Ext. of licorice, fine powder.gr. 15 Acacia, fine powder gr. 15 Tolu balsam gr. 150 Ether fl.dr. 4 Water sufficient To the reduced iron, contained in a small mortar, add i l / 2 fluidrams of wa- ter, and then, gradually, the iodin, con- stantly stirring until the liquid ceases to have a reddish tint. Then add the re- maining powders, previously well mixed together, and mix the whole thorough- ly. Transfer the mass to a porcelain capsule, and evaporate the excess moist- ure on a water bath, with constant stir- ring, until the mass has acquired a pilu- 300 STANDARD FORMULARY OF lar consistence. Then divide into ioo pills. Dissolve the balsam in the 4 fl. dr. ether, shake the pills with a sufficient quantity of this solution until they are uniformly coated, and put them on a plate to dry, occasionally rolling them about until the drying is completed. Keep the pills in a well-stoppered bottle.— U. S. P. These are practically the same as Blancard's pills. Each pill contains about i grain of ferrous iodid with an excess of iron. Pills, Jalap. Jalap soap parts 3 Jalap, powder part 1 Make into i^-grain pills. — Germ. Pharm. Pills, Janeway's. See Pills of Aloes and Podophyllum, Compound. Pills, Laxative. Thomsonian (from the Materia Med- ica) : Poplar or peach extract oz. 1 Bitter root oz. y 2 Ox-gall, dried oz. y 2 Mix well, and add a small amount of capsicum. Make a mass and divide into pills (number not stated). Pill, Laxative, Compound. Each pill should contain Aloin gr. 1/5 Strychnine (alkaloid) gr. 1/120 Ext. belladonna leaves gr. 1/8 Ipecac gr. 1/16 Licorice root gr. 7/10 Simple syrup sufficient — N. F. This formula is very similar to that of a number of proprietary pills, but the latter usually contain 1/60 grain of strychnine. Pills, Laxative Post Partum, Bark- er's. (Laxative Pills after Con- finement.) Each pill should contain Comp. ext. of colocynth. . . .gr. 12/3 Purified aloes gr. 5/6 Extract of nux vomica gr. 5/12 Resin of podophyllum gr. 1/12 Ipecac gr. 1/12 Extract of henbane gr. 1 1/4 This is the formula generally em- ployed by Dr. Fordyce Barker, except where special circumstances render modifications necessary. The formula usually quoted in manufacturers' lists and some formularies is not correct. — N. F. Pills of Leptandra, Compound. (Com- pound Pills of Culver's Root.) Each pill should contain Extract of leptandra gr. 1 Resin of podophyllum gr. l / 2 Extract of rhubarb sufficient Some prefer to make the mass with extract of dandelion instead of extract of rhubarb. — Eclectic. This is a cholagogue, useful in liver affections, obstinate constipation, etc. Pills, Lobelia, "Compound. Lobelia seed, fine powder oz. 4' Capsicum, fine powder oz. 4 Acacia, fine powder oz. 1 Water, enough to form a mass. Divide into pills (number not stated). — Thomsonian (from Comfort's Prac- tice). Pills, Mixed Treatment. Each pill should contain Red mercuric iodid gr. 1/20 Potassium iodid gr. 5 Pills, Metallic. (Bitter Metallic Pills — Pilulse Metallorum.) Each pill should contain Reduced iron gr. 1 Quinine sulfate gr. 1 Strychnine (alkaloid) gr. 1/20 Arsenous acid gr. 1/20 — N. F. These are similar to Aitken's Tonic Pills (see Pills, Tonic, Aitken's). Pills of Myrrh. This formula has been credited to Thomsonian practice: Myrrh tablespoonful 1 Acacia teaspoonful 1 Sugar teaspoonful 1 Make into pills. Pills, Neuralgia. See Pills, Antineuralgic. PHARMACEUTICAL PREPARATIONS. 301 Pills No. 3. These are from hydro-alcoholic ex- tract of bayberry root bark. — Thomsoni- an (from Comfort's Practice). In some formularies the formula giv- en is equal parts of capsicum and ex- tract of bayberry. Another name given to the latter is anti-canker pills. See Pills, Anti-Canker. Pills, Opium. Each pill should contain Opium, powder gr. I Soap, castile gr. 3/10 Water sufficient The corresponding preparation of the Brit. Pharm. is called compound pill of soap which is prepared from 1 av.ounce each of powdered opium and syrup of glucose and 3 of powdered castile soap. Dose, 2 to 4 grains. Pills of Opium and Camphor. Each pill should contain Opium, powder gr. 1 Camphor gr. 2 — N. F. Pills of Opium and Lead. (Pills of Lead and Opium.) Each pill should contain Opium, powder gr. 1 Lead acetate gr. 1 Pills of Opium, Digitalis and Quinine. To make 100 pills : Powdered opium gr. 15 Digitalis, fine powder gr. 100 Quinine sulphate gr. 100 Clarified honey, q. s. Pills, Phosphorus. I. Phosphorus gr. 1 Althea, No. 60 powder gr. 90 Acacia, fine powder. gr. 45 Tolu balsam gr. 150 Ether fl.dr. 4 Chloroform, glycerin, water, each sufficient Dissolve the phosphorus in a test- tube in 80 minims of chloroform, with the aid of a very gentle heat, replacing from time to time any of the chloroform which may be lost by evaporation. Mix 'he althea and acacia in a mortar, next add the solution of phosphorus, then immediately afterwards a sufficient quantity (about 1 fluidram) of a mix- ture of 2 volumes of glycerin and 1 of water, and quickly form a mass, to be divided into 100 pills. Dissolve the tolu balsam in the 4 fl. dr. ether, shake the pills with a sufficient quantity of this solution until they are uniformly coated, and put them on a plate to dry, occasionally rolling them about until the drying is completed. Keep the pills in a well-stoppered bottle.— U. S. P. II. Phosphorus gr. 10 White wax gr. 125 Lard gr. 125 Kaolin gr. 115 Carbon disulfid m. 33 or sufficient Place the wax and lard, previously melted, in a slightly warmed mortar, and stir until the mixture has the con- sistence of Cream. Dissolve the phos- phorus in the carbon disulfid and care- fully mix the solution with the melted fats, add the kaolin, and mix well to- gether. Keep the mixture immersed in cold water in a bottle from which the light is excluded (amber bottle, for example). —Brit. Pharm. W T hen dispensed, every 3 grains of the mass is to be mixed with 1 grain of powdered acacia, and the resulting pills should be varnished. Phosphorus Pill, including the acacia, contains 2 per cent, of phosphorus, hence is nearly double the strength of the Phosphorus Pill of the Brit. Pharm. 1885. Dose, 1 to 2 grains. Pills of Podophyllin, Compound. Each pill should contain Podophyllin gr. l / 2 Scammony gr. ': Gamboge . ; gr. J .. — Eclectic. These are used for their cathartic ef- fect, one or two pills being taken every 302 STANDARD FORMULARY OF night or several times a week, as may be required. Owing to the difficulty of obtaining pure scammony, extract of apocynum or of rhubarb, or irisin. is sometimes substitutped for it by the Eclectics. Pills of Podophyllum, Belladonna and Capsicum. (Squibb's Podo- phyllum or Laxative Pills.) Each pill should contain Resin of podophyllum gr. % Extract of belladonna leaves.. gr. x /s Capsicum, moderately fine powder gr. Vi Sugar of milk, fine powder. . . .gr. I Acacia, fine powder gr. l /± Glycerin, simple syrup, each sufficient Pills of Poke, Compound. Extract of poke leaves gr. 30 Extract of stillingia gr. 15 Ext. of stramonium leaves... gr. 2 Make 16 pills. — Eclectic. Pills, Quadruples. (Quatuor Pills — Compound Pills of Iron and Qui- nine.) Each pill should contain Sulfate of iron, dried gr. I Quinine sulfate gr. 1 Purified aloes gr. 1 Extract of nux vomica gr. Ya Extract of gentian sufficient — N. F. Pills of Quinine Sulfate. I. Quinine sulfate gr. 60 Aromatic sulphuric acid... drops 45 Make into 60 pills. — Eclectic. II. Quinine sulfate gr. 30 Tartaric acid, powder gr. 1 Glycerin gr. 4 Tragacanth, powder gr. 1 Triturate the quinine sulfate with the acid, add this to the tragacanth and glycerin which have previously been mixed, and make a mass. — Brit. Pharm. Dose, 2 to 8 grains. Pills of Quinine, Compound. Quinine sulfate gr. 60 Extract of dogwood gr. 60 Tartaric acid gr. 60 Extract of black cohosh. . .sufficient Divide into 4-gr. pills. — Eclectic. The above is the formula as it is given. Pills, Bhubarb. Each pill should contain Rhubarb, No. 60 powder gr. 3 Soap, castile, fine powder gr. 1 Water sufficient — N. F. Pills, Rhubarb, Compound. Each pill should contain Rhubarb gr. 2 Aloes, purified gr. 1 1/2 Myrrh gr. 1 Oil of peppermint m. 1/12 Mix the oil with the powders and make mass with water. — U. S. P. Compound Rhubarb Pill, Brit. Pharm., is made from 2 av.ounces of rhubarb, 1J/2 of socotrine aloes, 1 each of myrrh and castile soap, 1 fluidram of oil of peppermint, and l$4 av.ounces or suf- ficient of syrup of glucose. Dose, 4 to 8 grains. Pills, Rhubarb, Wuerzburger. (Kneipp's Pills.) Each is said to be composed of Rhubarb gr. 1 Extract of aloes gr. 1 Extract of rhubarb gr. 1/4 Soap gr. 1/4 Juniper berry gr. 3/40 Fenugreek gr. 3/40 Dwarf elder gr. 3/40 Fennel gr. 3/40 Pill, Scammony, Compound. Resin of scammony av.oz. 1 Resin of jalap av.oz. 1 Curd soap, powder av.oz. 1 Tincture of ginger fl.oz. 3 Add the tincture to the soap and resins, dissolve by the aid of a gentle heat, and evaporate on a water bath to suitable consistency. — Brit. Pharm. Dose, 4 to 8 grains. Pills, Scot's. See Pills, Anderson's Scot's. Pills of Soap, Compound. (Diuretic Pills.) Oil of spearmint fl.dr. 1 Oil of juniper berries fl.dr. 1 Oil of sassafras fl.dr. 1 Castile soap gr. 90 Beat the soap in a mortar, gradually adding the oils, thoroughly incorporating PHARMACEUTICAL PREPARATIONS. 303 after each addition, and, when all is added, divide into 18 pills. — Eclectic. These are stimulant and diuretic, use- ful in gravel and chronic urinary affec- tions. For the Compound Pill of Soap of the Brit. Pharm., see Pill, Opium. Pill, Squill, Compound. Squill, powder av.oz. 1%. Ginger, powder av.oz. I Gum ammoniac, powder. .. .av.oz. I Castile soap, powder av.oz. I Syrup of glucose av.oz. i or sufficient Dose, 4 to 8 gr. — Brit. Pharm. Pills, Sumbul, Goodell's, Each pill should contain Extract of sumbul gr. I Ferrous sulfate, dried gr. i Asaf etida gr. 1/2 Arsenous acid gr. 1/40 Pills, Tonic, Aitken's. Each pill should contain Reduced iron gr. 2/3 Quinine sulfate gr. I Strychnine (alkaloid) gr. 1/50 Arsenous acid gr. 1/50 Honey, sufficient — N. F. These are similar to Pills, Metallic. Pills, Townsend's. It is said that pills of this name should each be made from Mass of mercury gr. 1 1/4 Gamboge gr. 1 1/4 Extract of aloes gr. 1 1/4 Ginger gr. 1 1/4 Oil of peppermint drop 3/16 Pills, Triplex. (Pilulae Triplices— Compound Pills of Scammony.) I. Regular formula : Each pill should contain Purified aloes gr. 2 Mass of mercury gr. 1 Resin of podophyllum gr. yi — N. F. When Pilula Triplex, under this name or some equivalent, is prescribed with- out further specification, it is recom- mended that the above preparation be dispensed. A formula devised by Dr. John W. Francis is also in use: II. Francis' Triplex Pill : Each pill should contain Purified aloes gr. 5/6 Scammony gr. 5/6 Mass of mercury gr. 5/6 Croton oil m. 1/20 Oil of caraway m. 1/4 Tincture of aloes and myrrh (U. S. P.) sufficient — N. F. The following is said to be the origi- nal formula of Dr. J. W. Francis: Scammony ("gum"), powd..gr. 120 Aloes, socotrine, powder. .. .gr. 120 Mass of mercury gr. 120 Croton oil . . .^ m. 5 Oil of caraway m. 22 Tincture of aloes and myrrh. m. 30 Make 100 pills. The pill furnished by manufacturing houses corresponds to the latter form- ula, not to that of the N. F. Pills of Valerian, Compound. Extract of scullcap gr. 60 Extract of Roman chamomile-.gr. 60 Extract of boneset gr. 30 Quinine sulfate gr. 30 Capsicum gr. 10 Oil of valerian gr. 15 Make into 45 pills. — Eclectic. These pills are tonic and nervine, the dose being one every 2 or 3 hours. Pills of Viburnum, Compound. (Com- pound Pills of High Cranberry or Cramp Bark.) Each pill should contain Extract of cramp bark gr. ^4 Extract of blue cohosh gr ^ Extract of mitchella gr. i l / 2 Useful in uterine diseases, the dose being 1 or 2 pills 3 times a day. — Ec- lectic. Pills, Warburg. See Pills, Antiperiodic. Pills of Wild Indigo, Compound. (Compound Pills of Baptisia.) Each pill should contain Extract of leptandra gr. 1/4 Resin of podophyllum .gr. 1/2 Sanguinarin gr. 1/16 Extract of wild indigo, enough to form a mass. This is a cholagogue, laxative and antiseptic, useful in typhoid fever. — Ec- lectic. 304 STANDARD FORMULARY OF Pills of Zinc Acetate, Rademacher's. Each pill should contain Zinc acetate gr. 3 Extract of licorice sufficient — H. Plasters. (Emplastra.) These are solid compounds, of fatty- character, intended for external use. They are harder than cerates, are to be spread by heat on cloth, leather, etc., and in this form are applied to the body to which they adhere. The spread plasters of the market consist of plasters of the above charac- ter spread on suitable material or they have a caoutchouc (india-rubber) in- stead of a fatty vehicle. The U. S. P. recognizes one spread plaster, viz., cap- sicum. Plaster, Aconite. Fluid extract of aconite fl.oz. 4 Lead plaster av.oz. Z X A Evaporate the extract to soft extract consistency, add the plaster, previously melted, and stir constantly until thor- oughly incorporated and the whole is nearly cold. — Eclectic. Plaster, Adhesive. Rubber, cut in small pieces. av.oz. l /$ Petrolatum, yellow av.oz. % Lead plaster av.oz. 12 Melt the rubber at a temperature not exceeding 150 deg. C, add the petrola- tum and continue the heat until the rubber is dissolved. Add the lead plas- ter to the hot mixture, continue the heat until it becomes liquid, then strain, allow it to cool and stir until it stiffens — U. S. P., 1900. This was introduced into the 1900 U. S. P. to replace the resin plaster of the U. S. P. 1890 in making other plasters, such as belladonna, opium and capsicum plasters. Plaster, Ammoniac. Gum ammoniac av.oz. 5 Diluted acetic acid fl.oz. 7 Digest the ammoniac with the diluted acetic acid, in a suitable vessel, avoid- ing contact with metals, until it is en- tirely emulsionized ; then strain and evaporate the strained liquid, by means of a water bath, stirring constantly, un- til a small portion, taken from the ves- sel, hardens on cooling. — U. S. P. 1880. Plaster, Ammoniac, with Mercury. (Ammoniac and Mercury Plas- ter.) I. Gum ammoniac av.oz. 3 Mercury av.oz. }i Oleate of mercury gr. 15 Diluted acetic acid fl.oz. 4 Lead plaster, to make av.oz. 4. .gr. 75 Digest the ammoniac with the acid, in a closed vessel, avoiding contact with metals, until the gum is entirely emulsi- fied, then strain, and evaporate the strained liquid by means of a water bath, stirring constantly, until a small portion taken from the vessel hardens on cooling. Triturate the oleate with the mercury, gradually added, until globules of metal cease to be visible. Next add gradually the ammoniac while yet hot, then enough lead plaster, pre- viously melted on a water bath, to make 4 av.ounces, 75 gr., and mix the whole thoroughly.— U. S. P. 1890. II. Ammoniac plaster.. .part by weight 1 Plaster of mercury, eclectic parts by weight 2 — Eclectic. III. Ammoniac av.oz. 3 Mercury (metal) av.oz. $4 Olive oil gr. 14 Sulfur gr. 2 Heat the oil, add the sulfur to it grad- ually, stirring until they are uniformly blended; with this mixture triturate the mercury until metallic globules are no longer visible. To this add the am- moniac, previously purified by boiling with successive portions of water, pass- ing the resulting emulsions through a hair sieve, rubbing the residues on the latter; after mixing, evaporate the emul- sions to suitable consistence. — Brit. Pharm. PHARMACEUTICAL PREPARATIONS. 305 Plaster, Arnica. I. Extract of arnica root av.oz. i Resin plaster av.oz. 2 Add the extract to the plaster, pre- viously melted on a water bath, and mix them thoroughly.— U. S. P. 1890. II. Fluid ext. of arnica flowers. fl.oz. 16 Resin plaster av.oz. 4 Burgundy pitch av.oz. 1 Evaporate the fluid extract on a wa- ter bath to a soft extract weighing about 2 av.ounces, then add the resin plaster and p'tch previously melted. — Eclectic. Plaster, Aromatic. (Spice Plaster.) Clove av.oz. 1 Cinnamon, saigon av.oz. 1 Ginger av.oz. 1 Capsicum av.oz. Y2 Camphor av.oz. Y2 Cottonseed oil av.oz. 3^2 Lead plaster av.oz. 2.y 2 Melt tcrether the plaster and oil, with the aid of heat. Cool the mixture and, while it is still soft, thoroughly incorporate with it the aromatic ingre- dients, previously reduced to a very fine powder. Plaster, Asafetida. Asafetida -. av.oz. iYa Lead plaster av.oz. iYa Galbanum av.oz. Y Yellow wax av.oz. Y Alcohol fl.oz. 6 Digest the asafetida and galbanum, both in coarse powder, with the alcohol on a water bath, separate the liquid portion, while hot, from the coarser impurities by straining, and evaporate it to the consistence of honey; .then add the lead plaster and the wax, previously me'.tcd together, stir the mixture well, and evaporate to the proper consistence. — U. S. P. 1880. Plaster, Bayberry. (Green Salve — Emplastrum Myricae.) Gum turpentine, Bayberry wax, each equal parts Melt together, strain, and stir until cool.— Eclectic. In winter a small quantity of olive or cottonseed oil may be added. Plaster, Belladonna. • Extract of belladonna leaves. parts 3 Adhesive plaster, U. S. P... parts 7 Melt the adhesive plaster on a water bath, add to it the extract of belladonna leaves, previously softened by the heat of a water bath, and continue the heat, stirring constantly until the mixture is perfectly homogeneous, then allow to cool.— U. S. P. 1900. Belladonna plaster should contain not less than 0.38 to 0.42 per cent, of mydri- atic alkaloids. It is customary for druggists to retail over their counters the spread belladonna plasters of the factories which are made with a rubber base. The U. S. P. requires that these also should assay not less than 0.35 nor more than 0.40 per cent of mydriatic alkaloids. The belladonna plaster of the U. S. P. 1890 was made with resin and soap plasters as a base. The plaster of the Brit. Pharm. is made by evaporating 6 x /i fluidounces of liquid (fluid) extract of belladonna, Brit. Pharm., on a water bath until it weighs 1Y2 av.ounces, then incorpora- ting yYz av.ounces of resin plaster, pre- viously melted. This latter plaster contains 0.5 per cent, of the alkaloids of belladonna root. The Brit. Form, recognizes a "green belladonna plaster" made by mixing al- coholic extract of belladonna leaf, such a quantity as contains 11 grains of al- kaloid, with enough resin plaster to make 10 av.ounces. This is half the alkaloidal strength of the belladonna plaster of the Brit. Pharm. Plaster of Belladonna, Compound. Resin plaster av.oz. 5 Extract of belladonna root. av.oz. 1 Extract of conium leaves, .av.oz. 1Y2 Iodin gr. 40 Place the plaster in a porcelain or wedgewood mortar and put this into hot water. When the plaster begins to melt- 306 STANDARD FORMULARY OF add the extract, and incorporate thor- oughly. Then remove the mortar from the water, allow to become cool, add to its contents the iodin, previously re- duced to powder, and continue the trit- uration until the whole is well mixed. The inspissated juices are preferred to the above extracts for this prepara- tion. The extracts as usually made in England from the fresh drugs would answer the requirements. — Eclectic. Plaster, Burgundy Pitch. See Plaster, Pitch, Burgundy. Plaster, Canada Pitch. (Hemlock Pitch Plaster — Hemlock Plaster — Emplastrum Picis Canadensis.) Canada or hemlock pitch (so- called hemlock gum) . . .av.oz. 4 Yellow wax gr. 175 Melt them together, strain the mix- ture, and stir constantly until it thick- ens on cooling.— U. S. P. 1880. Plaster, Cancer. Thomsonian (from the Guide) : Extract red clover heads by boiling with water, expressing, and evaporating to a thin extract. Plaster, Cantharides. (Emplastrum Cantharides, Epispasticum or Lyttae.) I. Cantharides, powder av.oz. 3^2 Yellow wax av.oz. 2 Lard av.oz. 2 Resin av.oz. 2 Soap plaster av.oz. ^2 Melt the resin, add the plaster, and afterwards the wax and lard, sprinkle the cantharides into the melted mixture, and stir the latter continuously while cooling. — Brit. Pharm. II. The preparation of the Germ. Pharm. called "ordinary cantharides plaster" is made as follows : Cantharides, moderately fine.av.oz. 2 Olive oil av.oz. 1 Soft turpentine av.oz. 1 Yellow wax av.oz. 4 Heat the cantharides with the oil on a water bath for 2 hours, add the wax and turpentine, allow all to meit to- gether, remove the dish from the source of heat, and stir until cold. The Germ. Pharm. also recognizes a perpetual and a veterinary cantharides plaster. Plaster, Cantharides, Perpetual. (Emplastrum Cantharides Per- petuum — Immerwaehrendes Spanischfliegen Pilaster.) Cantharides, moderately fine.av.oz. 1 Gum euphorbium, moderate- ly fine av.oz. y A Mutton suet av.oz. 1 Soft turpentine av.oz. 1^ Yellow wax av.oz. 2. l / 2 Resin av.oz. 3^ Melt the resin with the turpentine, add the suet and wax, when all is melt- ed, incorporate the two powders, and stir until cold. — Germ. Pharm. Plaster, Cantharides, Veterinary. Cantharides, coarse powder. av.oz. 3 Gum euphorbium, moderate- ly fine powder av.oz. 1 Resin av.oz. 6 Soft turpentine ,. . . av.oz. 6 Melt the resin, add the turpentine, incorporate the powders, and stir till cold. — Germ. Pharm. Plaster, Capsicum. Oleoresin of capsicum ,gr. 2 l /2 Rubber plaster, spread on fabric sufficient Over a piece of spread adhesive plas- ter 6 inches square, apply the oleoresin, painting it with a suitable brush over the surface of the plaster, but leaving a margin around the sides of the latter. — U. S. P. Plaster, Capsicum, Compound. (Com- mon Strengthening Plaster — Sear-Cloth Plaster.) Resin av.oz. 4 Yellow wax av.oz. 1 Tincture of capsicum, U. S. P fl.oz. 5 Camphor, powder av.oz. y 2 Oil of sassafras m. 45 Melt the rosin and wax, add the tinc- ture, and keep the whole at a gentle heat, stirring constantly, until the alco- hol has evaporated; then remove from the fire, and when nearly cold add the camphor and oil. — Eclectic. PHARMACEUTICAL PREPARATIONS. 307 It would be much more convenient to substitute 2 fluidrams of fluid extract of capsicum for the tincture. Plaster, Court. See Plaster, Isinglass. Plaster, Galbanum. (Compound Gal- banum Plaster, U. S. P. 1870 — Compound Lead or Drachylon Plaster.) Galbanum av.oz. 1 Gum turpentine gr. 55 Burgundy pitch gr. 165 Lead plaster av.oz. 4% To the galbanum and turpentine, pre- viously melted together and strained, add, first, the pitch, then plaster, melted over a gentle fire, and mix the whole thoroughly.— U. S. P. 1880. Galbanum Plaster, Brit. Pharm. 1885 (not in 1898 edition), is prepared from 1 av. ounce each of galbanum, ammoniac and yellow wax and 8 av.ounces of lead plaster. Melt the galbanum and am- moniac together, strain, and add the wax and plaster, previously melted to- gether. The latter is more similar than the former to compound lead plaster, Germ. Pharm. See Plaster, Lead, Compound. Plaster, Galbanum, Bed. (Oxycro- ceum Plaster — Ochsenkreuz Pnaster.) Resin av.oz. 3 Yellow wax av.oz. 1 ^ Ammoniac av.oz. 34 Galbanum av.oz. 34 Venice turpentine av.oz. ^4 Olibanum, fine powder gr. 395 Mastic, fine powder gr. 395 Spanish saffron, fine powder, previously moistened with alcohol gr. 198 Melt together the resin and wax, also the galbanum and ammoniac with the Venice turpentine at a gentle heat. When the former has partially cooled, add the second mixture, and then in- corporate the remaining ingredients. — Austr. Pharm. The ammoniac and galbanum should have previously been purified by repeat- ed boiling with water and evaporating the emulsion. 20 Previous editions of the same work directed powdered ammoniac and galba- num instead of the whole gums puri- fied. A cheap substitute is the following : Burgundy pitch av.oz. 5*4 Yellow wax av.oz. 3^ Soft turpentine .av.oz. 2^ Red saunders, fine powder, .av.oz. 1%. Beef suet av.oz. 34 Heat the saunders and turpentine in a closed vessel, on a water bath, for 1 hour, melt the other ingredients to- gether, strain, add the saunders mixture, and stir until concreted. — D. Plaster, Iron. (Strengthening Plas- ter.) Iron (ferric) hydrate, fresh- ly prepared and dried at a temperature not exceeding 80 deg. C av.oz. 3/ 4 (gr. 330) Olive oil gr. 180 or fl.dr. 3*4 Burgundy pitch gr. 510 Lead plaster av.oz. 6 Melt the plaster and pitch by means of a water bath, add the oil, then add the hydrate, and stir constantly until the mixture thickens on cooling. — U. S. P. 1890. Plaster, Isinglass. (Court Plaster— Emplastrum Ichthyocollae — Em- plastrum Adhaesivum Anglicum.) I. Isinglass, Russian gr. 150 Alcohol gr. 6©@ or fl.dr 12^ Glycerin gr. 15 Water, Tincture of benzoin, each, .sufficient Dissolve the isinglass in enough hot water to make the solution weigh 4 av.ounces. Spread one-half of this, in successive layers, upon taffeta (stretched on a frame), by means of a brush, waiting after each application until the layer is dry. Mix the second half of the isinglass solution with the alcohol and glycerin, and apply it in the same manner. Then reverse the taffeta, coat it on the back with the tincture of ben- zoin, and allow it to become perfectly dry. Cut the plaster in pieces of suitable length and preserve in well-closed ves- sels.— U. S. P. 1890. 308 STANDARD l-'ORMULARY OF The above directions are sufficient to cover a piece of taffeta 15 inches square. II. Isinglass, cut as fine as pos- sible av.oz. Yi Sugar gr. 5 Water, alcohol, tincture of benzoin, each sufficient Heat the isinglass with 2 fluidounces of water in a covered vessel on a water or steam bath until most of it is dis- solved, strain, treat the undissolved resi- due again with the same amount of water, strain again, mix the strained liquids, evaporate to a weight of 3 av.- ounces, and add the sugar, dissolving the latter by agitation. When the liquid has become tolerably cool, apply it by means of a soft, broad brush, upon silk taffeta stretched on a frame, in separate coats, the first three being applied in a cool room, the subsequent ones in a moderately warm room. Each coat must be dried before the next is ap- plied. The back of the taffeta is to be coated with tincture of benzoin diluted with an equal volume of alcohol. — Germ. Form. The Yz av.ounce of isinglass should coat about 480 square inches of cloth. The U. S. P. formula has the advan- tage of using glycerin, which prevents the plaster from cracking. Plaster, Lead. (Diachylon Plaster — Litharge Plaster — Emplastrum Plumbi or Lithargyri.) I. Soap, dried and in coarse powder av.oz. 10 Lead acetate av.oz. 6 Distilled water sufficient Dissolve the soap in 35 fluidounces of hot water and strain the solution, also dissolve the lead acetate in 25 fluid- ounces of hot water, and at once filter the lead solution into the warm soap solution, stirring constantly. When the precipitated lead oleate has sub- sided, decant the liquid, and wash the precipitate thoroughly with hot water. Transfer the mass to a warm slab and knead it thoroughly to free it from wa- ter. Finally roll the plaster into the form of a cylinder and wrap in paraf- fined paper.— U. S. P. 1900. The soap for this preparation should be a pure olive oil soap such as a cas- tile soap of known purity. This should be cut into rather small cakes, dried by exposure to the air, then grated and again dried by exposure to the air. Or in lieu of drying in this manner, the amount of moisture in the soap may be determined by examination and then proportionately more of the soap used in making the preparation. The lead acetate should be perfectly pure, not an ordinary commercial ar- ticle. Only distilled water should be used. This process of making lead oleate in U. S. P. 1900 was intended to replace the boiling process of the U. S. P. 1890, given herewith. It is somewhat similar to the present U. S. P. process, which see in No. IV. Lead oxid av.oz. 8 Olive oil av.oz. 15 Water sufficient Triturate the oxid, previously passed through a No. 80 sieve, with about one- half of the oil until well mixed, and add to the remainder of the oil contained in a bright copper boiler of a capacity equal to at least 4 times the bulk of the ingredients. Then add 2^ fluid- ounces of boiling water and boil the whole together over a fire, stirring con- stantly with a wooden spatula, scraping the spatula frequently along the sides and bottom of the boiler, until a small portion taken out and dropped into cold water is found to be pliable and tena- cious. From time to time add a little water to replace that lost by evapora- tion. When the contents of the boiler has acquired a whitish color and is per- fectly homogeneous, transfer it to a vessel containing warm water, and as soon as the mass has cooled sufficiently, knead it well with water so as to re- move the glycerin which has been formed during the above reaction, re- PHARMACEUTICAL PREPARATIONS. 309 newing the water from time to time as may be necessary to remove all of the glycerin. Dry the mass and divide into rolls of suitable size.— U. S. P. 1890. If the heat be continued too long, the plaster will become discolored; if not continued long enough, there will be uncombined oxid. III. Lead oxid av.oz. 8 Olive oil av.oz. 16 Distilled water fl.oz. 8 or sufficient Boil all the ingredients together gen tly by the aid of a steam bath; keep simmering for 4 or 5 hours, stirring constantly until the product acquires the proper consistence for plaster ; add more water during the process if necessary. — Brit. Pharm. IV. Lead oxid, No. 80 powd av.oz. 5 Olive oil, common av.oz. 5 Lard av.oz. 5 Boiling water sufficient Heat the olive oil and lard by a gentle heat in a bright copper or other suitable container, until liquefied. Sift the lead oxid upon the surface of the hot liquid and stir thoroughly. Gradually add 2y 2 fluid ounces boiling water and boil the mixture, stirring with a wooden spatula, replacing the water lost by evaporation. Wash several times with warm water to remove the glycerin, knead until free from water, and roll into cylinders. — U. S. P. Plaster, Lead, Compound. (Com- pound Diachylon or Litharge Plaster — Gummi Pflaster. . .av.oz. 6 ..av.oz. Y\ ..av.oz. y> ..av.oz. y 2 ..av.oz. y 2 Lead plaster Yellow wax Ammoniac Galbanum Soft turpentine Melt the plaster and wax together at a gentle heat and strain; also melt the ammoniac and galbanum with the tur- pentine, strain, and add this to the par- tially cooled plaster and wax mixture. ' — Germ. Pharm. This is somewhat akin to galbanum plaster. See Plaster, Galbanum. Plaster, Lead Iodid. Lead iodid, fine powder. .. .av.oz. y 2 Resin av.oz. y 2 Lead plaster av.oz. 4* Melt the resin and plaster together at as low a temperature as possible, and incorporate the lead iodid. — Brit. Pharm. Plaster, Lead, White. (Emplastrum Cerussce — Emplastrum Album Coctum — Plaster of Lead Carbon- ate. Lead carbonate, fine powder.av.oz. s J A Olive oil av.oz. 1 Lead plaster av.oz. 6 Water sufficient Triturate the lead carbonate to a per- fectly smooth paste with the oil, add this mixture to the lead plaster pre- viously melted on a water bath, continue the heat, occasionally adding a small amount of water, and stirring continu- ously, until a suitable plaster mass is formed. — Germ. Pharm. Plaster, Logan's. Lead oxid av.oz. 2 Lead carbonate av.oz. 2 Castile soap av.oz. i l / 2 Butter, fresh av.oz. y 2 Olive oil fl.oz. 5 Mastic, powder gr. 15 Mix the soap, oil and butter, add the lead oxid, and boil the whole gently for an hour and a half or until it has acquired a pale-brown- color, stirring constantly meanwhile; the heat may then be increased and the boiling con- tinued till a portion of the melted plas- ter dropped on a smooth board is found not to adhere ; then remove the vessel from the fire and add the mastic to the mixture. Plaster, Lumbago. (Hexenschuss Pflaster.) Kneipp's : Dispense burgundy pitch plaster. Plaster, Menthol. Menthol av.oz. 1 ^ Yellow wax av.oz. 1 Resin av.oz. y l / 2 Melt the resin and wax together; when the mixture approaches the tern- 310 STANDARD FORMULARY OF perature of 71 to 77 deg. C, stir in the menthol until dissolved — Brit. Pharm. This contains 15 per cent, of menthol. Plaster, Mercurial. (Emplastrum Hydrargyri.) I. Mercury (metal) av.oz. i l / 2 Oleate of mercury gr. 22 Wool fat, hydrous av.oz. */> Lead plaster, to make av.oz. 5 Triturate the mercury with the oleate until the metal is thoroughly divided, then add the wool fat and continue the trituration until the globules of mer- cury are no longer visible. Add the previously been melted in a tared dish, and incorporate thoroughly, adding if necessary enough more lead plaster to make the product weigh 5 av.ounces. II. Mercury av.oz. 1J/2 mixture to the lead plaster, which has Olive oil gr. 28 Sulfur gr. 4 Lead plaster av.oz. 3 Heat the oil, add the sulfur to it gradually, stir until uniformly blended, with this mixture triturate the mercury until metallic globules are no longer visible, and incorporate the lead plaster which has previously been melted. —Brit. Pharm. III. Mercury av.oz. 3 Resin av.oz. 1 Olive oil rl.dr. 9 Lead plaster av.oz. 6 Melt the resin, add the oil, allow to cool, add the mercury, triturate until the latter is extinguished, then add the lead plaster previously liquefied. — Eclec- tic. IV. Mercury av.oz. 1 Wool fat, anhydrous av.oz. J^ Yellow wax av.oz. Yi Lead plaster av.oz. 3 Triturate the mercury with the wool fat until well mixed, then incorporate with the previously melted and par- tially cooled mixture of wax and plas- ter. — Germ. Pharm. Plaster, Miraculous, Pvademacher's. Red lead av.oz. 4 Olive oil av.oz. 8 Amber, powder gr. 84 Camphor, powder gr. 56 Burnt alum, fine powder gr. 28 Water sufficient Boil the lead and oil with some wa- ter, according to the method of making mother plaster, until a black plaster is formed, allow to cool somewhat, and ncorporate the other ingredients. — H. This may be made directly from cam- phorated mother plaster as follows: Camphorated mother plas- ter av.oz. 4 Amber, powder gr. 28 Burnt alum, fine powder gr. 9 — H. Plaster, Mother, Camphorated. (Mother Plaster — Camphorated Brown Plaster — Emplastrum Fuscum or Fuscum Camphora- tum — Emplastrum Matris Cam- phoratum — Nuremburg or Uni- versal Plaster.) Red oxid of lead (red lead) av.oz. 3 Olive oil av.oz. 6 Yellow wax av.oz. 1^2 Camphor gr. 45 Triturate the red oxid of lead with a portion of the oil in a capacious cop- per kettle to a smooth paste. Then add the remainder of the oil, excepting a small quantity required for trituration with the camphor, and boil the whole over a naked fire, under constant stir- ring, until gas bubbles rise, or until the red color of the mixture begins to turn brown. Then moderate the heat, but keep up the stirring until the mixture has acquired a dark-brown color, and from time to time allow some drops of it to fall into cold water to test its con- sistence. When this is satisfactory (i. e., can be kneaded between the fingers), remove the vessel from the fire, add the wax in small pieces, and finally the cam- phor, previously rubbed to a smooth paste with a little olive oil. Mix thor- oughly, allow the mixture to become somewhat cool, and while it is still PHARMACEUTICAL PREPARATIONS. 311 warm, pour the plaster into paper molds previously coated with mucilage con- taining about 5 per cent, of glycerin, and dried. — N. F. and Germ. Pharm. The olive oil intended to be used for this preparation is the common grade having a greenish color. In place of it, cottonseed oil may be used. If desired, the camphor may be omit- ted; it often is. Sometimes / 2 to i av.ounce of black pitch is added to the above mixture. The Germ. Pharm. does not direct a copper vessel, but this is preferred. Plaster Mulls. See Mulls, Plaster and Salve. Plaster, Opium. (Emplastrum Odon- talgicum or Cephalicum.) Extract of opium gr. 260 Adhesive plaster av.oz. 9 Water fl.dr. 6^ Rub the extract with the water until it is uniformly soft, also melt the plaster in a tared dish on a water bath, add the softened extract, and continue the heat with constant stirring until the product weighs 10 av. ounces. Opium plaster of the Brit. Pharm. is made from 1 av.ounce of opium in very fine powder, with 9 av.ounces of resin plaster. Plaster, Pitch. (Emplastrum Picis.) I. See Plaster, Pitch, Burgundy. II. Burgundy pitch lb. 1 Venice turpentine lb. 1 Capsicum, powder ..'.... oz. 1 Melt together and if too hard, remelt and add a small amount of sweet oil. — Thomsonian (from Comfort's Prac- tice). Plaster, Pitch, Burgundy. I. Burgundy pitch av.oz. 4 Yellow wax av.oz. Y\ Olive oil av.oz. l / A Melt the pitch and wax, incorporate the oil, and stir constantly until the mass thickens on cooling, — U, S. P. 1890, _ II. Pitch Plaster: Burgundy pitch av.oz. 4 Olibanum av.oz. 2 Resin gr. 300 Yellow wax gr. 300 Olive oil gr. 135 Distilled water fl.dr. 2}/ 2 Add the oil and water to the oliba- num, pitch, resin and wax, previously melted together, and evaporate with constant stirring to proper consistence. —Brit. Pharm. Plaster, Pitch, Canada or Hemlock. See Plaster, Canada Pitch. Plaster, Pitch, Cantharidal. (Warm- ing Plaster.) I. Cerate of cantharides gr. 140 Burgundy pitch, to make, .av.oz. 4 Melt the cerate on a water bath con- taining boiling water, and continue the heat for 15 minutes; then strain it through a piece of muslin of close tex- ture so that the cantharides will be retained on the muslin. To the strained cerate, add enough pitch to make the whole weigh 4 av.ounces, render the mixture homogeneous by stirring, re- move the heat, and stir the mass until it thickens on cooling. II. Emplastrum Calefaciens or Warm- ing Plaster: Cantharides, coarse powder. av.oz. y 2 Yellow wax av.oz. V 2 ...av.oz. y 2 . . .av.oz. 4 ...av.oz. 6 l / 2 fl.oz. 2 l / 2 Resin Soap plaster Resin plaster Distilled water, boiling Infuse the cantharides in the water for 6 hours, express strongly in muslin, evaporate the liquid on a water bath until reduced to one-third, add the other ingredients, melt on a water bath, and stir until well mixed.— Brit. Pharm. A somewhat simpler formula than this, using the ingredients of the resin and soap plaster, is this: Cantharides av.oz. l / 2 Yellow wax av.oz. l / 2 Castile soap av.oz. 1 Resin av.oz. VA Lead plaster av.oz. 8& Water fl.oz. 2 X x Prepare as before. 312 STANDARD FORMULARY OF Plaster, Resin. (Emplastrum Ad- hsesivum — Adhesive or Sticking Plaster— Heft Pflaster.) Yellow wax av.oz. Y Resin, fine powder av.oz. iY Lead plaster av.oz. 10 Melt the lead plaster and wax to- gether at a gentle heat, add the resin, and when it is melted, mix the mass thoroughly.— U. S. P. 1890. P. 1890. The adhesive plaster of the U. S. P. 1900 was intended to replace the above. See Plaster, Adhesive. II. The Brit. Pharm. directs l / 2 av.- ounce of castile soap. 1 of resin, and 8 of lead plaster. Melt each separately at a low temperature, and mix. III. Lead plaster av.oz. 4 Paraffin wax av.oz. *4 Liquid paraffin av.oz. x /\ Caoutchouc (rubber) av.oz. 1 Dammar av.oz. 1 Resin av.oz. 3^ Petroleum benzin av.oz. yV 2 (fl.oz. 11) Heat the lead plaster on a water bath for some time until thoroughly free from water, add the two paraffins, and, when melted, add a previously melted mixture of the dammar and resin, and then add the rubber dissolved in the benzin ; finally heat the mixture cau- tiously on a water bath, stirring con- stantly meanwhile, until the benzin has been completely dissipated. — Germ. Pharm. Plaster, Resin, Compound. (Adhe- sive and Strengthening Plaster.) White resin av.oz. 12 Yellow wax av.oz. 1 Burgundy pitch av.oz. 1 Suet av.oz. 1 Olive oil fl.dr. 1 Oil of sassafras fl.dr. 1 Camphor, powder gr. 60 West India rum fl.oz. 1 Melt the first four ingredients to- gether, then add the other substances, incorporate thoroughly, pour the whole into cold water and work with the hands till cold, and form into rolls. —Eclectic. The pouring into and working in wa- ter is, however, an unnecessary proce- dure. The rum also serves no good purpose and may be omitted. Another Eclectic formula, preferred by some, is the following: Resin av.oz. 12 Yellow wax av.oz. 1 Oil of hemlock fl.dr. 2 Oil of sassafras fl.dr. 2 Oil of turpentine fl.dr. 1 Olive oil fl.dr. 2 Camphor gr. 55 Melt the resin and wax together, al- low to cool, and while still liquid add the camphor dissolved in the oils. Plaster, Soap. (Emplastrum Saponis or Saponatum.) Soap, castile, dried, coarse powder av.oz. 1 Lead plaster av.oz. 9 W T ater sufficient Rub the soap with enough water to reduce it to a semi-liauid state, then mix it with the lead plaster, previously melted, and evaporate it to the proper consistence. — N. F. The soap should be an olive-oil soap. such as castile soap is supposed to be. The Brit. Pharm. directs 1 /a av.ounce of resin, i l / 2 av. ounces of castile soap, and 9 of lead plaster. The Germ. Pharm. directs 7 av. ounces of lead plaster and 1 of yellow wax to be melted together at a moderate temperature, allowed to cool partially, adding l / 2 av.ounce of medicinal soap, powdered moderately fine, and 45 grains of camphor previously triturated with the same weight of olive oil, and stirred till cool. Plaster, Strengthening. Burdock leaves, Mullein leaves, each. .. .equal parts Water, Rosin, Turpentine, each sufficient Mix the fresh leaves, bruise in a mor- tar, boil thoroughly with sufficient wa- ter, strain and express, boil the liquid down to thin syrup, add 3 parts of rosin and 1 of turpentine and simmer till all the water has evaporated. Put PHARMACEUTICAL PREPARATIONS. 313 into cold water and knead with the hands. If too hard, add more turpentine; if too soft, add more rosin. — ThomsOnian (from the Guide and Materia Medica). Another strengthening plaster by Thomson was made from 2 ounces of rosin, 1 teaspoonful of powdered cap- sicum and enough lard to give the prop- er consistence. Plaster, Tar, Compound. (Irritating Plaster.) Resin av.oz. 5 Pine tar av.oz. 4 Mandrake root, No. 60 pow- der av.oz. 1 Poke root, No. 60 powder. ..av.oz. 1 Bloodroot, No. 60 powder, .av.oz. 1 Melt the resin and tar together, then stir in the mixed powders, and as the mass cools, mold it into rolls, or pour it into boxes. The above is a slightly modified Ec- lectic formula which is as follows : Burgundy pitch av.oz. 3 Gum turpentine av.oz. 2 Pine tar av.oz. 6 Mandrake root av.oz. 1%. Bloodroot . . . . av.oz. 1% Poke root av.oz. 1% Indian turnip av.oz. 1% Melt the pitch and turpentine togeth- er, add the tar, strain, add the other ingredients in fine powder, and incor- porate well together. When it is desired to have a more active preparation, and one which will act more promptly, add Vz av.ounce euphorbium, in powder to the above. Plaster, Warming-. (Emplastrum Calefaciens.) See Plaster, Pitch, Cantharidal. Plaster, White Lead. See Plaster, Lead, White. Potassa, Sulfurated. (Liver of Sul- fur — Hepar Sulfuris — Sulfurated Potash — Sulfuret of Potassium.) Sulphur, sublimed ....av.oz. 1 Potassium carbonate, dried. av.oz. 2 Mix the powdered and dried potas- sium carbonate thoroughly with the sul- fur, and gradually heat the mixture, in a covered crucible (Hessian), which should be not more than half filled with it, until the mass ceases to foam and is in a state of perfect fusion. Then pour the fused mass on a cold marble slab, and, after it has cooled, break it into pieces and keep in a well-stoppered bot- tle.— U. S. P. 1890, Brit. Pharm. and Germ. Pharm. Potio Biveri. See Solution of Sodium Citrate. Poultices. (Cataplasms.) A number of eclectic, Thomsonian, and other formulas for cataplasms (poul- tices) are here included. While the pharmacist does not, as a rule, make these preparations, it is only proper that he should have knowledge of them. The U. S. P., Germ. Pharm. and Brit. Pharm. 1898 do not recognize any poul- tices, but several are mentioned in the Brit. Pharm. 1885 and in the Codex. See Cataplasma Kaolini. Poultice. Thomsonian (from the Guide) : Make a strong tea of raspberry leaves or of No. 3, take a cracker, pounded fine, and powdered slippery elm bark, with some ginger, and make a poultice. Poultice, Alum. Alum '. gr. 30 White of one egg. Mix well. Poultice, Bread. Heat crumbs of bread with enough sweet milk to form a poultice. A little fresh lard may be added, which pre- vents the skin from becoming sodden and wrinkled. Poultice, Carrot. (Cataplasma Dauci or Carotse.) Carrots, fresh, scraped av.oz. 4 Corn meal av.oz. 1 Water, boiling, enough to make a cataplasm. — Eclectic. Poultice, Capsicum. Capsicum, powder, Slippery elm, powder, each. . equal parts Water, warm, to form a poultice. — Thomsonian (from Comfort's Prac- tice) . 314 STANDARD FORMULARY OF Poultice, Catnip. Catnip leaves steeped in water and thickened with slippery elm, ground flaxseed or fine corn meal.— Thomsonian (from Comfort's Practice). Poultice, Charcoal. (Cataplasma Carbonis.) I. Bread av.oz. 2 Linseed meal gr- 600 Wood charcoal, powder gr. 180 Water fl - oz - IO Macerate the bread, for a short time, with the water, in a warm place, to soften it, then gradually add the linseed, stirring so as to make a uniform mix- ture. Then add 120 grains of charcoal, and when the poultice is prepared for application, sprinkle on its surface the remaining 60 grains of charcoal. . The formula of the Brit. Pharm. 1885 differs from this in directing i l / 2 av.- ounces of linseed and y 2 av.ounce of charcoal. II. Charcoal, powder parts 3 Slippery elm. powder parts 2 Ginger, powder part 1 Water, warm, to make a poultice. —Thomsonian (from Comfort's Prac- tice). Poultice, Chlorin. (Chlorinated Soda Poultice — Chlorin Cataplasm — Cataplasma Sodee Chlorinata.) Linseed meal av.oz. 4 Water, boiling fl.oz. 8 Solution of chlorinated soda. fl.oz. 2 Mix the linseed meal with the water and gradually add the solution. — Brit. Pharm. 1885. Poultice, Corn Meal (Indian Meal Poultice.) Stir corn meal into boiling water un- til of the proper consistence. Poultice, Cranberry. (Cataplasma Oxycocci.) Eclectic : This is simply bruised ripe cranber- ries. Poultice, Elm or Slippery Elm. (Cataplasma Ulmi.) Stir powdered slippery-elm bark into hot water, or a mixture of water and milk, sufficient to form a poultice. — Ec- lectic. Poultice, Emollient and Stimulant. Slippen,' elm. powder parts 2 White pond lily root, powder.part 1 Cracker, pounded part 1 Water, warm, to form a poultice. — Thomsonian (from Comfort's Prac- tice). Poultice, Hemlock. (Cataplasma Conii.) Hemlock juice fl.oz. 1 Linseed meal av.oz. 4 Water, boiling fl.oz. 10 Evaporate the juice to y 2 fluidounce, and incorporate this with the meal and water previously mixed. — Brit. Pharm 1885. The extract or fluid extract of conium might be used instead of the juice. though the juice only is directed by the Brit. Pharm. Poultice, Linseed or Flaxseed. (Cata- plasma Lini, Emolliens or Com- munis.) Linseed meal av.oz. 4^2 or sufficient Water, boiling fl.oz. 10 To the water add the linseed meal or sufficient to form a suitable poultice. The Brit. Pharm. 1885 directed 4 av.- ounces of linseed meal to 10 fluidounces of boiling water. Poultice, Lobelia. (Cataplasma Lo- belise.) To equal parts of powdered lobelia and slippery-elm bark, add sufficient of a weak lye. — Eclectic. Poultice, Molasses. Add wheat flour to molasses in suffi- cient quantity to form a soft poultice. This is a useful application for burns and scalds. Poultice, Mustard. (Cataplasma Sin- apis or Rubefaciens—Sinapism.) Mustard, white and black mixed, powder av.oz. 2j^ Linseed meal av.oz. 2 l / 2 Water sufficient Mix the mustard with 2 or 3 fluid- ounces of boiling water, the linseed meal PHARMACEUTICAL PREPARATIONS. 315 with 6 or 8 fluidounces of boiling wa- ter, and then mix the two together. — Brit. Pharm. 1885. Neither vinegar nor any alcoholic liquid should be used in making mustard poultice. Poultice, Myrrh. Equal quantities of the residue from No. 6 and slippery elm powder and add enough water to make a poultice. — Thomsonian (from Comfort's Practice). Poultice, Poke Root. (Cataplasma Phytolacca.) Place fresh pokeroot in hot ashes to roast, and when sufficiently done, mash it and form a poultice. — Eclectic. Poutice, Potato. This is simply mashed boiled potatoes. Poultice, Spice. This is a domestic poultice prepared from the ordinary household spices, us- ing equal measures of ground mustard, ginger, clove, cinnamon and allspice, and making into a poultice with warm vine- gar. Poultice, Stimulant and Astringent. Composition powder, Slippery"' elm, powder, each, equal parts. Water, warm, to make a poultice. Lard, a small amount. — Thomsonian (from Comfort's Prac- tice). Poultice, Stramonium. (Cataplasma Stramonii.) Bruise fresh stramonium leaves and add a small quantity of hot water, suf- ficient to form a poultice. — Eclectic. Poultice, Wild. Indigo. Bark of the fresh root of wild indigo powdered fine. — Thomsonian (from Comfort's Practice). Poultice, Yeast. (Cataplasma Fer- menti.) I. Milk, tepid fl.oz. 8 Yeast fl.oz. 2 Slippery elm bark, powder, enough to make a poultice. — Eclectic. The formula of the Brit. Pharm. 1885 differed in directing 6 fluidounces of yeast to be mixed with an equal volume of water at 38 deg. C, incorporating 14 av. ounces of wheat flour, and placing near the fire until fermentation ensues when bubbles of carbonic acid gas are given off. 11. To yeast add a mixture of equal parts of ginger and rye or wheat flour, and put in a warm place till it be- gins to rise. — Thomsonian (from Com- fort's Practice). Powder of Acacia, Compound. (Pul- vis Gummosus.) Acacia, fine powder parts 3 Licorice, fine powder parts 2 Sugar, fine powder part 1 — N. F. III. The Germ. Pharm. directs 5 parts of acacia, 3 of licorice, and 2 of sugar. The Swed. Pharm. directs a mixture of 1 part of althea, 2 of acacia, and 2 of sugar, and for this the proper title is Compound Powder of Althea. Powder of Acetanilid, Ammoniated. Sodium bicarbonate part 1 Ammonium carbonate parts 2 Acetanilid parts 5 Sugar of milk parts 12 Triturate the ammonium carbonate and acetanilid intimately together, add the sodium bicarbonate and milk sugar, and mix thoroughly. — Cine. Acad. Pharm. Each 10 gr. contains 2^ gr. acetanilid, 1 gr. of ammonium carbonate and ^2 gr. of sodium bicarbonate. The powder is (said to be) readily soluble in water. The mixture should be preserved in well stoppered bottles. It has no depressing effects like ace- tanilid alone but on the contrary it stimulates the heart and circulatory sys- tem. Powder of Acetanilid, Compound. I. Acetanilid parts 7 Sodium bicarbonate parts 2 Caffeine (alkaloid) part 1 This is a favorite mixture in this country, especially for headache pow- ders,— N, F, and Brit. Form. 316 STANDARD FORMULARY OF II. Acetanilid parts 50 Sodium bicarbonate parts 45 Caffeine (alkaloid) parts 2 Tartaric acid parts 3 Reduce the ingredients separately to a fine powder and mix them thoroughly. This preparation is popularly pre- scribed in New Orleans, under the name of "Kamna-Fuga," as an antipyretic, and is claimed to have some advantages over acetanilid by itself. Powder of Almond, Compound. (Con- fection of Almond.) Sweet almond parts 6 Sugar, fine powder parts 3 Acacia, fine powder parts 1 Blanch the almonds, then dry them thoroughly with a soft cloth, and rub them lightly in a mortar, until they form a mass of a smooth consistence. Mix the acacia and sugar, add them to the mass previously prepared, and rub the whole to a coarse powder, which is to be preserved in a lightly covered jar. If 820 grains of this preparation be thoroughly triturated with 17 fluidounces of water, gradually added, and the mix- ture finally strained, the product will be about 16 fluidounces of Emulsion of Al- mond, U. S. P.— N. F. The Brit. Pharm. directs 8 parts of almond, 4 of sugar and 1 of acacia. The almonds, after blanching, should be dried in a warm place for 24 hours. Powder of Aloes and Canella. (Hiera Picra — Aloetic Powder — Holy- Bitter.) Purified aloes parts 4 Canella part 1 Both should be in fine powder and be intimately mixed. — N. F. Powder, Alum, Comp'd, Squibb's. Camphor part 1 Carbolic acid, crystal parts 2 Dried alum, fine powder. . .parts 47 Dissolve the camphor in the liquefied carbolic acid, and thoroughly incorpor- ate this with the alum. This is used for indolent ulcers and sores, especially for veterinary use. Powder, Anticatarrhal. See Snuff, Catarrh. Powder, Antimonial. (James' Pow- der — Jacob's Powder — Pulvis Jacobi — Compound Powder of Antimony — Pulvis Antimonial- is.) Antimony oxid part 1 Calcium phosphate, precipi- tated parts 2 — N. F., U. S. P. 1890 and Brit. Pharm. Dose of Brit. Pharm. : 3 to 6 grains. Powder, Antiseptic, Soluble. Salicylic acid gr. 5 Carbolic acid gr. 1 Eucalyptol gr. 1 Menthol gr. 1 Thymol gr. 1 Zinc sulfate gr. 128 Boric acid, impalpable pow- der gr. 888 Triturate the salicylic acid and zinc sulfate to very fine powder; add the carbolic acid, eucalyptol, menthol and thymol, and continue the trituration, adding the boric acid, in small portions at a time, until a uniform impalpable powder is obtained. — N. F. Powder, Aromatic. Cinnamon saigon, No. 60 powder parts 7 Ginger, Jamaica, No. 60 powder parts 7 Cardamom, deprived of the capsules and crushed parts 3 Nutmeg, No. 20 powder parts 3 Triturate the cardamom and nutmeg with a portion of the cinnamon, until they are reduced to a fine powder, then add the remainder of the cinnamon and the ginger, and rub them together until they are thoroughly mixed. — U. S. P. The corresponding preparation of the Brit. Pharm. is called Compound Pow- der of Cinnamon, and is prepared from equal parts of Ceylon cinnamon, carda- mom seed, and Jamaica ginger. Powder, Arsenical, Come's. (Cosmi's Powder.) Red mercuric sulfid parts 30 Arsenous acid parts 10 Dragon's blood parts 3 Charcoal, animal parts 2 Triturate together to a very fine pow- der.«-Germ. Pharm. 1st. PHARMACEUTICAL PREPARATIONS. 317 Powder of Bayberry, Compound. (Ce- phalic Powder — Pulvis Myricse Compositus.) Bayberry bark, powder, Bloodroot, powder, each, equal parts — Eclectic. This is used alone or combined with common snuff as a snuff in catarrh, headache, etc. The Thomsonian preparation known as Composition Powder (see Powder, Composition) is also known by the above name. Powder of Bismuth, Compound. The following was a favorite combin- ation of Dr. S. H. Tewksbury, Port- land, Me., now deceased. Since his death it has seemingly become popular- ized, and generally prescribed by phy- sicians all over the country. It is not infrequently prescribed as Mistura Bis- muthi Comp. Acacia, powder, Sugar, powder, Ginger, powder, Sodium bicarbonate, Bismuth subnitrate, each, equal parts Each article to be added separately and thoroughly incorporated and finally passed through a fine sieve. Powder, Black. (Emmenagogue Pow- der — Pulvis Nigrum.) Sulfur av.oz. i Myrrh av.oz. I Steel filings ....av.oz. i Loaf sugar av.oz. i White wine fl.oz. 8 Mix, and, by aid of a gentle heat, evaporate till nearly dry ; pulverize the mass when cold. — Eclectic. This is the formula as originally given. The substance is best dispensed in pill form. It is used in idiopathic amenorr- hea, chlorosis, etc., in doses of 30 grains, times a day. *owder of Calomel and Jalap. (Calo- mel and Jalap.) Calomel gr. 10 Jalap, fine powder gr. 20 Mix intimately. When "Calomel and Jalap" is pre- scribed for an adult, without any speci- fication of quantities, it is recommended that the above mixture be dispensed as one dose. — N. F. Powder of Camphor, Compound. Tannic acid parts 2 Kino parts 2 Camphor parts 2 Opium part 1 Eeach should be in fine powder and the whole should be well mixed. — Eclec- tic. Make into 3K gr. powders. Powder, Cancer, Esmarch's. (Pulvis Anticarcinomaticus Esmarch — Pulvis Causticus Esmarch — Es- march's Caustic Powder.) Arsenous acid part 1 Morphine hydrochlorid ....part 1 Calomel parts 8 Acacia, powder parts 48 — H. Powder of Catechu (Gambir) Comp. Catechu (Gambir, U. S. P.) .parts 4 Kirto parts 2 Phatany parts 2 Cinnamon parts 1 Nutmeg part 1 All should be in fine powder. Mix them intimately, pass the powder through a fine sieve, and afterwards rub it lightly in a mortar.. Keep in a stoppered bottle. — N. F. and Brit. Pharm. The dose given by the Brit. Pharm. is 10 to 4*0 grains. Powder of Chalk, Aromatic. (Pulvis Cretce Aromaticus.) Cinnamon, Saigon parts 4 Nutmeg parts 3 Clove parts i^A Cardamom part 1 Prepared chalk parts 11V2 Sugar parts 26 Mix the ingredients and reduce them to a fine powder. Pass this through a fine sieve, and afterwards rub it lightly in a mortar. Keep it in a stoppered bottle. This preparation is equivalent to the Pulvis Cretan Aromaticus of the Brit. Pharm. 1885 except that Spanish saffron was added. This authority adds the following fnote: "If a produ t of bright color be desired, the saffron may previ- ously be moistened and triturated with 318 STANDARD FORMULARY OF a little water or alcohol, or the fresh and faintly damp mixture may be sub- jected to considerable pressure in the triturating process."— N. F. The preparation of the Brit. Pharm. 1885 differed from the above only in having 11 parts of chalk and 25 of sugar. The present Brit. Pharm. differs from the 1885 edition in directing no saffron. Powder of Chalk with Opium, Aro- matic. Aromatic powder of chalk. parts 39 Powdered opium part 1 Mix it intimately. Every 40 grains of this preparation contain 1 grain of powdered opium. — N. F. and Brit. Pharm. Powder, Chalk, Compound. Prepared chalk parts 3 Acacia, fine powder parts 2 Sugar, fine powder parts 5 — U. S. P. On no account should precipitated chalk be used in mixture, as is some- times done. Powder of Charcoal, Compound. (Pulvis Carboni Ligni Composi- tus.) Wood charcoal parts 4 Rhubarb parts 2 Sodium bicarbonate part 1 All should be in fine powder and the whole well mixed. — Eclectic. This is useful in dyspepsia attended with acidity-, loss of appetite, distress after eating, etc. Powder of Cinnamon, Compound. See Powder, Aromatic, for this prep- aration of the Brit. Pharm. Powder, Clarifying. I. To facilitate the obtaining of per- fectly bright solutions of essential oils in water, the use of a mixture of pow- dered paper, asbestos and kaolin in some such proportions as the following has been recommended: Paper powder (obtained by rubbing dried white filter paper through a No. 20 sieve) part 1 Asbestos, sifted part 1 Kaolin parts 20 Mix lightly together, finally sifting. The powder should be shaken up with the turbid liquid for a few minutes and poured on the oreviously wetted filter, the filtrate being returned until it passes through bright, which it does in a short time. The powder is not lim- ited in its use to the solutions men- tioned, but answers well for other liquids also. II. D. recommends this mixture for wines, liqueurs and other alcoholic li- quids : Egg albumen, dried parts 2 Sugar of milk parts 2 Starch part 1 Reduce all to No. 80 powder and mix well. For one pint of liquid, use 8 to 4c grains of powder, according to the tur- bidity, agitate thoroughly, let stand for several days in a warm place, agitating occasionally, and filter. Powder, Composition. (Compound Powder of Bayberry — Vegetable Powder — Vegetable Cold Powder — Pulvis Myricae Compositus.) Bayberry root bark parts 12 Ginger parts 6 Capsicum part 1 Clove part 1 Reduce the substances to a moderately fine powder, and mix thoroughly. — N. F. In Thomson's Guide appears this for- mula: Bayberry root bark lb. 2 Inner bark of common hem- lock lb. 1 Ginger lb. 1 Capsicum - oz. 2 Clove oz. 2 All to be in fine powder, and well mixed. In the Thomsonian Materia Medica appear three "preparations" : First preparation is bayberry, 2 pounds, ginger, 1 pound, capsicum, 2 ounces, clove, 2 ounces. Second preparation is bayberry, gin- ger, poplar, and hemlock bark, each, 1 pound, red or white oak bark, y 2 pound, capsicum, 3 ounces, and clove, 2 ounces. Third preparation is bayberry and gin- PHARMACEUTICAL PREPARATIONS. 319 get each, 2 pounds, poplar and oak bark, each, 1 pound, capsicum, 3 ounces, and clove, 2 ounces. In Comfort's Thomsonian Practice of Medicine this formula is given : Bayberry root bark lb.. . 3 Ginger lb. I Yz Capsicum oz. 3 Clove oz. 3 All in fine powder; mix well. For the similar eclectic preparation, see Powder of Bayberry, Compound. Powder, Cooling. (Pulvis Refriger- ans — Kjoelende Pulver.) Oil sugar of lemon part 1 Potassium nitrate parti Potassium bicarbonate parts 6 — Danish Pharm. The formula of the Norw. Pharm. differs from the above only in directing 6 1/3 parts of potassium bicarbonate. Powder, Cough. Mix 4 teaspoonfuls of skunk cabbage, 2 of hoarhound, 1 of Indian turnip, 1 of lobelia herb, 1 of capsicum, 1 of bayberry bark, 1 of dogsbane, and 1 of ladies' slipper root, all in powder and well mixed. To be taken in molasses. — Thomsonian (from the Guide). Lobelia herb, Licorice root, Skunk cabbage root, each equal parts — Thomsonian (from Comfort's Prac- tice). Powder of Culver's Root, Compound. See Powder of Leptandra, Compound. Powder of Cypripedium, Compound. See Powder of Ladies' Slipper, Com- pound. Powder, Digestive, Momberger's. Rhubarb parts 2 Senna parts 2 Magnesium carbonate parts 2 Potassium bitartrate part 1 Oil-sugar of anise part 1 Reduce all to fine powder and mix well. Powder, Dover's, Camphorated. (Beach's Diaphoretic Powder — Compound Powder of Ipecac and Opium.) I. Opium part 1 Ipecac parts 2 Camphor parts 4 Potassium bitartrate parts 16 All should be in powder and should be well mixed. — Eclectic. There are other forms of camphorated Dover's powder in occasional use, as follows : II. Selle's: Ipecac gr. 2 Opium gr. 4 Camphor gr. 8 Sugar gr. 160 This is intended for 8 powders. III. Richter's : Ipecac gr. 1 Opium gr. 2 Camphor gr. 1 Sugar. gr. 12 IV. Von Graefe's: Ipecac gr. 3 Opium gr. 6 Camphor gr. 30 Sugar t . . gr. 60 This is intended for 6 powders. See also the regular Dover's powder, Powder of Ipecac and Opium. Powder, Dusting, Anderson's. (Pul- vis Anderson — Anderson's Pow- der — McCaull Anderson's Dust- ing Powder.) This is a sedative drying powder em- ployed by the famous London specialist in certain forms of wet eczema. The composition is variously given. These formulas are appended. I. Starch 1 .parts 16 Zinc oxid parts 8 Camphor part 1 II. Starch parts 16 Zinc oxid parts 3 Camphor part 1 III. Starch _ parts 16 Zinc oxid parts 4 Camphor parts 3 The latter was used by a prominent local physician making a specialty of skin diseases. An impalpable powder must be pro 320 STANDARD FORM duced by passing through fine bolting cloth. Preserve in well-corked, wide-mouthed bottles. Powder, Dyspeptic. Capsicum oz. 4 Golden seal lb. V2 Poplar bark lb. 4 Sugar, brown lb. 8 All in fine powder, mix well, and in- corporate one ounce of essence of pennyroyal. — Thomsonian (from the Materia Medica). Powders, Effervescent. See Salts, Effervescent. Powder, Effervescing. (Pulvis Aero- phorus.) Sodium bicarbonate parts 26 Tartaric acid parts 24 Sugar parts 50 Or use 53^ av. ounces of bicarbonate, 5 of acid, and 10^/2 of sugar. All should be in fine powder and per- fectly dry, and should then be well mixed. — Germ. Pharm. Preserve in well-stoppered bottles in a dry place. Powder, Effervescing, with. Mag- nesia. (Pulvis Aerophoms Cum Magnesia.) Tartaric acid part 1 Oleosaccharate of lemon. .. .parts 2 Sugar, moderately fine pow- der parts 3 Magnesium carbonate parts 4 — Germ. Form. Prepare and preserve like the preced- ing. Powder of Elaterin, Compound. Elaterin part 1 Sugar of milk parts 39 Triturate in a mortar until a fine powder is produced*. Dose, 1 to 4 grains.— Brit. Pharm. Powder of Golden Seal, Compound. (Compound Powder of Hydras- tis.) Golden seal, Blue cohosh, Helonias, each equal parts Reduce to fine powder. — Eclectic. ULARY OF Powder, Gun. (Pulvis Pyrius — Pul- vis Nitratis.) Ordinary gunpowder is prepared by mixing five or six parts of potassium nitrate with one part each of wood charcoal and sulfur. However, the pro- portions used by different manufacturers vary more or less. Gunpowder was formerly used a great deal in medicine but its only pharmaceutical use now is as an occasional ingredient of veterin- ary prescriptions. The following combination may be used for gunpowder when the latter is needed for veterinary or other mix- tures : Potassium nitrate parts 15 Charcoal parts 3 Sulfur parts 2 Powder, Gun, White. This formula may be used : Potassium ferrocyanid part 1 Sugar part 1 Potassium chlorate parts 2 Reduce each to powder separately, then mix well, but very carefully, using a bone or wooden spatula. Powders, Homeopathic. See Medications, Homeopathic. Powder, Infant, Hufeland's. (Pulvis Infantium or Carminativum Hufeland — Pulvis Anodynus In- fantium — Pulvis Puerorum Citri- nus — Krampf, Wind, Kinder, or Beruhigungs Pulver.) Saffron, Spanish gr. 130 Anise av.oz. 1 ^2 Magnesium carbonate ....av.oz. 2 Valerian av.oz. 2 Orris av.oz. 2^2 All should be in fine powder and be well mixed. — H. A cheaper preparation used as a sub- stitute for the above is this : Valerian av.oz. ^ Rhubarb av.oz. i l /> Oleosaccharate of fennel. . .av.oz. 3 Magnesium carbonate av.oz. 6 — H. For other infant powders, see Powder of Magnesia and Rhubarb, Powder of Rhubarb, Compound, and Powder of Rhubarb and Magnesia, Anisated. PHARMACEUTICAL PREPARATIONS. 321 Powder of Iodoform, Compound. (Naphthalin Iodoform.) Iodoform, fine powder av.oz. 2 Boric acid, fine powder av.oz. 3 Naphthalene av.oz. 5 Oil of bergamot fl.dr. 2 Triturate the naphthalin with the oil, then mix it with the iodoform and acid, and triturate until a homogeneous pow- der is produced. This powder is used in many cases, where a diluted preparation of iodoform, for external purposes, is desired. The odor of the iodoform is masked both by the oil of bergamot and the naphthalene. Powder of Ipecac and Opium. (Dov- er's Powder — Compound Powder of Ipecac — Opiated Powder of Ipecac.) I. Ipecac, No. 60 powder part 1 Opium, powder part 1 Sugar of milk, No. 30 pow- der parts 8 Rub together to a very fine powder. — U. S. P. and Germ. Pharm. The U. S. P. 1870 directed potassium sulfate instead of milk sugar. The Brit. Pharm. also directs potassium sulfate. The Austr. Pharm. directs sugar instead of milk sugar or potassium sulfate. II. The Eclectic "compound powder of ipecac" is as follows : Ipecac, Pleurisy root, Bloodroot, Potassium nitrate, each, .equal parts Reduce to fine powder. See also Powders, Dover's, Camphor- ated. Powder of Ipecac and Opium, Com- pound. See Powder, Dover's, Camphorated. Powder of Jalap, Compound. (Pulvis "Purgans.) I. Jalap, No. 6b powder .parts 7 Potassium bitartrate parts 13 — U. S. P. II. Jalap parts 5 Potassium bitartrate .parts 9 Ginger part 1 All in fine powder, and be well mixed. —Brit. Pharm. III. The Eclectic "compound powder of jalap," also called Antibilious Physic (or A. B. Physic) is as follows: Senna, Alexandria av.oz. 2 Jalap av.oz. 1 Clove or ginger gr. 60 All should be in powder and be well mixed. This is an excellent purgative, the dose being 30 to 60 grains. Powder of Kino, Compound. (Powder of Kino and Opium.) Kino, fine powder parts 15 Powdered opium part 1 Ceylon cinnamon, fine pow- der parts 4 Mix them intimately, pass the mixed powder through a moderately fine sieve, and afterwards rub it lightly in a mor- tar. Keep it in a stoppered bottle. — N. F. and Brit. Pharm. Every 20 gr. of this preparation con- tain I gr. of powdered opium. Powder of Ladies' Slipper, Com- pound. (Nerve Powder.) Ladies' slipper root. Pleurisy root, Skunk cabbage root, Scullcap, each equal parts Reduce to fine powder. — Eclectic. Powder of Leptandra, Compound. Extract T>f leptandra, dried. parts 2 Resin of podophyllum part 1 Sugar of milk parts 10 This is used as a chologogue cathar- tic, the dose being 8 grains repeated every hour or two until it operates freely. — Eclectic. Powder, Licorice, Compound. (Pulvis Glycyrrhizae or Liquiritiae Com- positus — Pulvis Pectoralis or Kurellae — Kurella's or Pectoral Powder— Brust Pulver.) I. Licorice root, No. 80 pow- der av.oz. 1 1 M Senna, No. 80 powder. .. .av.oz. 9 Sulfur, washed av.oz. 4' Oil of fennel m. 100 Sugar, fine powder av.oz. 25 j Mix the oil thoroughly with about 32£ STANDARD FORMULARY OF one-half of the sugar, add the remainder of the sugar, and the other ingredients, mix thoroughly, and pass through a No. 60 sieve. Keep the product in well-closed ves- sels.— U. S. P. While the above is the formula of the present U. S. P., it is probable that the older formula is the one still in common use. It is as follows : Licorice root, fine powder. av.oz. 8 Senna, fine powder av.oz. 9 Sulfur, washed av.oz. 4 Fennel seed, fine powder, .av.oz. 4 Sugar, fine powder av.oz. 25 II. The formula of the Brit. Pharm. differs from the latter only in having 8 av. ounces of senna and 24 of sugar and in specifying sublimed instead of washed sulfur. III. Licorice root, fine powder. av.oz. 7 J/2 Senna, fine powder av.oz. 7M2 Fennel, moderately fine. . . .av.oz. 5 Sulfur, washed av.oz. 5 Sugar, moderately fine. .. .av.oz. 25 —Germ. Pharm. Powder of Lobelia, Compound. (Emetic Powder.) Lobelia herb gr. 60 Ipecac gr. 40 Bloodroot gr. 30 Skunk cabbage gr. 30 Capsicum gr. 10 Reduce all to fine powder and mix well. — Eclectic. Powder of Magnesia and Rhubarb. (Compound Powder of Magnesia — Pulvis Magnesia? cum Pvheo — Pulvis Infantium — Kinder Pul- ver — Infant Powder — Barne Pul- ver.) I. Magnesium carbonate parts 10 Oleosaccharate of fennel. . .parts 7 Rhubarb, fine powder parts 3 Mix well. — Germ. Pharm. II. Magnesium carbonate, Oil-sugar of fennel, Rhubarb, fine powder, each equal parts — Norw. Pharm. See also Powder of Rhubarb, Com- pound and Powder of Rhubarb and Magnesia, Anisated, both of which are similar. The similar Pulvis Infantium (or Puerorum) Ribke or Ribke's Infant Powder is composed of : Magnesium carbonate parts 12 Oleosaccharate of fennel. . .parts 8 Rhubarb parts 3 See also Powder, Infant, Hufeland's. Powder of Mandrake, Compound. (Pulvis Podophylli Compositus — Compound Powder of Podophyl- lum.) Mandrake parts 2 Blue flag parts 2 Bitter root (dogsbane) parts 2 Swamp milkweed (Asclepias incarnata) parts 2 Bloodroot part 1 — Eclectic. This is cathartic and alterative, used in obstinate constipation, dyspepsia, scrofulous, rheumatic and syphilitic af- fections, etc., in doses of 30 to 60 grains, 3 times daily. Powder, Milk, Humanized. Peptonizing powder gr. 35 Sugar of milk gr. 965 Mix well. This preparation is intended for con- venient use in preparing humanized milk. An even teaspoonful approxi- mates about 100 grains. Powder of Morphine, Compound. (Tully's Powder.) Morphine sulfate gr. 8 Camphor gum gr. 170 Licorice root, No.80powder.gr. 176 Precipitated chalk gr. 180 Alcohol sufficient Rub the morphine with the chalk, added in portions of about 5 grains each, until it is thoroughly mixed, then rub the camphor with a small amount of alcohol until it is reduced to a pow- der, and mix this intimately with the licorice and the other powders. Finally pass the powder through a No. 40 sieve, pulverize the residue if any should be left on the sieve, add to the sifted powder, and mix thoroughly. Transfer to a well-stoppered bottle. PHARMACEUTICAL PREPARATIONS. 323 Sixty-six and two-thirds parts of this powder contain one part of morphine sulfate. Dr. Brinsmade's modification of the above, which is also in use, is as fol- lows : Morphine sulfate gr. 8 Camphor gr. 160 Sugar gr. 160 Prepared chalk gr. 160 Tully's powder is used for the same purposes and in the same doses as Dover's Powder. Powder, Nephritic, Bademacher's. Cochineal, powder part i Calcined magnesia parts 4 — H. Powder, Nerve. Thomsonian (in Guide and Materia Medica) : This is powdered ladies' slipper root, also known as American valerian, um- bil, and male and female nervine. For the Eclectic nerve powder, see Powder of Ladies' Slipper, Compound. Powder of Opium, Compound. Opium parts 3 Black pepper parts 4 Ginger parts 10 Caraway parts 12 Tragacanth part 1 All should be in powder and should be well mixed. — Brit. Pharm. This contains 10 per cent, of opium. It is used principally for making con- fection of opium. Dose, 2 to 10 grains. Powder of Pepsin, Compound. (Pul- vis Digestivus.) Saccharated pepsin av.oz. 1 Pancreatin (U. S. P.) av.oz. 1 Diastase gr. 30 Lactic acid m. 30 Hydrochloric acid m. 60 Sugar of milk av.oz. 4^2 Add the acids gradually to the sugar of milk, and triturate until they are thoroughly mixed. Mix the pepsin, pan- creatin and diastase and then incorpor- ate this mixture, by trituration, with the sugar of milk mixture. Finally, rub the mixture through a hair sieve, and oreserve the powder in bottles. 21 The best commercial variety of dias- tase, capable of converting the largest comparative amount of starch into dex- trin and glucose, should be used for this preparation. The pepsin should be of the strength of 1 to 300. The pancrea- tin should be of the quality described under Powder, Peptonizing, which see. The lactic acid should contain 75 per cent, of absolute acid; the hydrochloric acid should contain 32 per cent, of abso- lute acid. Powder, Peptonizing'. (Compound Pancreatic Powder.) Pancreatin (U. S. P.) part 1 Sodium bicarbonate parts 4 Mix them by trituration. If pancreatin of proper strength is not available, any other commercial preparation of the pancreas, as, for in- stance, the extract, may be used in place of it, provided it attains the required standard. — N. F. The test of the U. S. P. for pancrea- tin is as follows : If there be added to 100 cc. of tepid water, contained in a flask, 0.28 gm. of pancreatin and 1.5 gm. of sodium bicar- bonate, and afterwards 400 cc. of fresh cow's milk previously heated to 38 deg. C, and if this mixture be maintained at the same temperature for 30 minutes, the milk should be so completely pep- tonized that if a small portion of it be transferred to a test tube and mixed with some concentrated nitric acid, no coagulation should occur. Peptonized milk prepared in the man- ner just described, or even when the process is allowed to go on to the de- velopment of a very distinct, bitter flavor, should not have an odor sugges- tive of rancidity. Twenty-five grains of the above pow- der are sufficient to peptonize 1 pint of fresh cow's milk, by proceeding in the following manner: Add the powder to 4 fluidounces of tepid water, contained in a suitable flask, and afterwards add 1 pint of fresh cow's milk, previously heated to 38 deg. 324 STANDARD FORMULARY OF C. Maintain the mixture at this tem- perature during 30 minutes, then trans- fer the flask to a cold place. Milk thus peptonized should not be used when it has been kept over 24 hours, or when it has developed a bitter taste. The N. F. also gives a formula for a diluted peptonizing powder intended for the convenient preparation of humanized milk under the name Powder, Milk, Hu- manized. Powder of Pink Root, Compound. (King's Entozoic Powder — Com- pound Powder of Spigelia.) Pink root part 1 Bitter root (dogsbane) part 1 Swamp milkweed (Asclepias incarnata) part 1 Podophyllum part 1 Balmony parts 2 All should be in very fine powder and the whole well mixed. — Eclectic. This is used as an anthelmintic. The dose for a child 1 year old is 5 to 8 grains given every hour or two until it operates freely. Powder of Pleurisy Root, Compound. (Pulvis Asclepias Compositus.) Pleurisy root parts 4 Spearmint parts 4* Sumach berries parts 4 Bayberry bark parts 2 Skunk cabbage parts 2 Ginger part 1 All should be in powder and should be well mixed. — Eclectic. Powder of Podophyllin, Compound. (Hydragogue Powder — Com- pound Powder of Resin of Podo- phyllum.) Podophyllin part 1 Potassium bitartrate parts 45 Mix well. — Eclectic. Dose, 20 grains every 2 hours until it operates sufficiently. Powder of Podophyllum, Compound. See Powder of Mandrake, Compound. Powder of Quinine, Compound. Quinine sulfate, Iron ferrocyanid, each, .equal parts Reduce to fine powder. This powder is tonic, febrifuge and antiperiodic. — Eclectic. Powder of Rhubarb, Compound. (Gregory's Powder — Gregory's Laxative Powder — Powder of Magnesia and Rhubarb— Pulvis Infantum — Pulvis Antacidus — Infant Powder — Kinder Pulver.) I. Rhubarb, No. 60 powder. . .parts 5 Light magnesia parts 13 Ginger, No. 60 powder parts 2 The proportions of the Brit. Pharm. are 4 of rhubarb, 12 of magnesia and 2 of ginger. This work states that if a less bulky powder is desired, the heavy magnesia may be used instead of the light variety. — U. S. P. See also Powder of Magnesia and Rhubarb and Powder of Rhubarb and Magnesia, Anisated, both of which are similar to the above. II. The Eclectic compound Powder of Rhubarb, also called Neutralizing Powder, is prepared as follows : Rhubarb, Potassium bicarbonate, Peppermint leaves, each, equal parts Each should be in fine powder and the whole should be well mixed. Powder of Rhubarb and Magnesia, Anisated. (Compound Anise Powder.) Rhubarb, fine powder. .. .av.oz. 2 Heavy calcined magnesia. av.oz. 4 Oil of anise fl.dr. 3^ Alcohol fl.dr. 4^ Mix the powders, add the oil previ- ously dissolved in the alcohol, and tritu- rate until a uniform mixture results. See also Powder of Rhubarb, Com- pound, and Powder of Magnesia and Rhubarb which are both similar to the above. — N. F. Powder of Scammony, Compound. Resin of scammony parts 4 Jalap parts 3 Ginger part 1 All should be in fine powder, and be well mixed. Dose. 10 to 20 grains. — Brit. Pharm PHARMACEUTICAL PREPARATIONS. 325 Powders, Seidlitz. (Compound Effer- vescing Powder — Effervescent Tartarated Soda Powder — Ab- fuehrendes Brause Pulver — Pul- vis Aerophorus Laxans or Seid- litzensis or Aperiens — Pulvis Ef- fervescens Compositus or Aperi- ens.) Sodium bicarbonate, dried and fine powder gr. 40 Rochelle salt, dried and fine powder gr. 120 Tartaric acid, dried and fine powder gr. 35 Mix the first two powders intimately and wrap in paper of some pronounced hue, such as blue. Wrap the acid in another paper of some color other than that used for the preceding, white, for example. Keep the powders in well-closed ves- sels.— U. S. P. The formula of the Brit. Pharm. dif- fers from the above only in directing 38 grains of tartaric acid. The Germ. Pharm. directs 2.5 grams of sodium, 2.7 of rochelle salt, and 2 of tartaric acid. Powder, Soda. (Effervescing Pow- der — Pulvis Effervescens — Pulvis Aerophorus Anglicus — Eng- lisches Brause Pulver — Brus Pul- ver.) Sodium bicarbonate gr. 30 Tartaric acid gr. 25 Both should be in fine powder. The two substances should be placed ■ in separate papers, like seidlitz powder, the sodium salt to be wrapped in a blue paper, the acid in a white paper. — U. S. P. 1870. The Germ., Norw. and Dan. Pharms. directs 2 grams of sodium bicarbonate and 1.5 of tartaric acid. Powder, Styptic. (Red Powder.) Ferrous sulfate, powder parts 2 Alum, powder part 1 Mix them and apply strong heat until a reddish product is obtained; powder when cold. — Eclectic. Powder of Sulfur and Cream of Tar- tar. (Sulfur and Cream of Tar- tar). The proper proportion for combining these substances is 1 part of sulfur and 2 of cream of tartar. Powder of Tragacanth, Compound. Tragacanth part 1 Acacia part 1 Starch part 1 Sugar parts 3 All should be in fine powder and be well mixed. "Starch" of the Brit. Pharm. is wheat, corn or rice starch. — Brit. Pharm. Pulp of Cassia Fistula. (Cassien Mus.) Free the pulp of cassia fistula as far as possible from the woody walls and partitions and the seeds, macerate in warm water till thoroughly softened, rub through a hair sieve, evaporate in a porcelain vessel to a very soft extract, to every 3 parts by weight of this, add 1 part of powdered sugar, and evapor- ate the whole on a water bath to suit- able consistence. — Austr. Pharm. Pulp, Colocynth. This is the dried pulp of the fruit of colocynth, freed from seeds. — Brit. Pharm. Pulp, Prune. (Pflaumen Mus.) Boil cut prunes with water, stirring constantly, until thoroughly softened, press through a hair sieve, and evapor- ate on a water bath to thick extract consistency. To every 3 parts by weight add 1 part of powdered sugar, and evap- orate on a water bath to suitable con- sistence. — Austr. Pharm. Pulp, Tamarind, Purified. (Tamar- inden Mus.) Soften commercial tamarind pulp uni- formly with hot water, rub through a coarse sieve, evaporate in a porcelain vessel on a. water bath to thick extract consistency, and to every 5 parts by weight of pulp add I part of powdered sugar. — Germ. Pharm. Pyroxylin. (Soluble Gun Cotton — Colloxylin — Collodion Cotton.) The present U. S. P. describes this as a product obtained by the action of nitric and sulfuric acids on cotton and consisting chiefly of cellulose tetranit- 326 STANDARD FORMULARY OF rate, but gives no process. The U. S. P. 1890, however, did give an excellent working process which is here given. I. Cotton, purified (absorb- ent) av.oz. 1 Nitric acid av.oz. 14 or fl.oz. g l /s Sulfuric acid. ..av.oz. 22 or fl.oz. n^> Alcohol, stronger ether, water, each sufficient Mix the acids gradually in a glass or porcelain vessel, and, when the temper- ature of the mixture has fallen to 32 deg. C, add the cotton. By means of a glass rod imbue it thoroughly with the acids, and allow it to macerate, until a sample of it, taken out, thoroughly washed with a large quantity of water, and subsequently with alcohol, and pressed, is foun \ to be soluble in a mixture of 1 volume of alcohol and 3 of stronger ether. Then remove the cotton from the acids, transfer it to a larger vessel, and wash it, first, with cold water, until the washings cease to have a sour taste, and then with boiling water, until they cease to redden blue litmus paper. Finally, drain the pyroxy- lin on filter paper, and dry it in small, detached pellets, by means of a water or steam bath, at a temperature not ex- ceeding 60 deg. C. — U. S. P. 1890. It should be kept in cartons, protected from light. Purified cotton, consists of almost pure cellulose, which is converted by the above treatment into cellulose nitrates. Other pure forms of cellulose may be used, but the cotton is the most con- venient. The acids must be of U. S. P. strength, the nitric, 68 p. c, the sulfuric, 92J/2 p. c, of absolute acid. II. Cotton, purified av.oz. 1 Sulfuric acid, pure, 92^ p. c. fl.oz. 5 Xitric acid, pure fl.oz. 4^ Distilled water sufficient Mix the acids in a porcelain mortar, immerse the cotton in the mixture, and after it is thoroughly wetted by the acids, stir it for 3 minutes with a glass rod; wash the cotton with distilled water until free from acid, drain it on filter paper, and dry on a water bath. — Brit. Pharm. III. Cotton, purified av.oz. 1 Nitric acid, crude av.oz. y l / A Sulfuric acid, crude av.oz. 18^4 Cautiously mix the nitric acid with the sulfuric acid; when the temperature of the liquid has become reduced to 20 deg. C, add to it the cotton, and allow- to remain at a temperature of 15 to 20 deg. C. Transfer the cotton to a fun- nel, allow the acid to drain for 24 hours, then wash with water until the washings are no longer acid, express the wool, and dry at a temperature not exceeding 25 deg. C. — Germ. Pharm. The crude sulfuric acid of the Germ. Pharm. contains 91 p. c. of absolute acid and has a sp. gr. of 1.83 ; the crude nitric acid contains 61 p. c. of absolute acid, sp. gr. 1.38 to 1.40. Rademacher's Preparations. Rademacher was a physician who lived about one hundred years ago in Ger- many. He entertained peculiar ideas re- garding the practice of medicine, as well as the preparation and action of drugs. Many of his peculiar preparations are prescribed in this country by the older German physicians, and more recently some of them have been employed by physicians partial to the Eclectic school. This class of preparations includes the following : 1. Drops, Dysmenorrhea. 2. Extract of Tobacco. 3. Magnesium Tartrate. 4. Mixture, Copper. 5. Mixture, Diarrhea. 6. Mixture, Iron. 7. Ointment, Calamine. 8. Ointment, Iodin. 9. Ointment, Shepherd's Purse. 10. Pills, Zinc Acetate. 11. Plaster, Miraculous. 12. Powder, Nephritic. 13. Solution of Calcium Chlorid. PHARMACEUTICAL PREPARATIONS. 327 14. Solution of Sodium Nitrate. 15. Solution, Anodyne Turpentine. 16. Tincture of Celandine. 17. Tincture of Cochineal. 18. Tincture of Colocynth Seed. 19. Tincture of Copper Acetate. 20. Tincture of Golden Rod. 21. Tincture of Hips. 22. Tincture of Iron Acetate. 23. Tincture of Mary Thistle. 24. Tincture of Mugwort Root. 25. Tincture of Nux Vomica. 26. Tincture of Shepherd's Purse. 27. Water, Acorn. 28. Water, Castor. 29. Water, Nux Vomica. 30. Water, Quassia. 31. Water, Tobacco. Formulas for making these prepara- tions may be found elsewhere in this book, under the proper respective head- ings. Resin of Cannabis Indica. See Extract of Cannabis Indica. Resin of Capaiba. The residue left after distilling the volatile oil from copaiba balsam. — U. S. P. 1890. Resin of Jalap. I. Jalap, No. 60 powder av.oz. 8 Alcohol, water, each sufficient Moisten the powder with 2^ fluid- ounces of alcohol, pack it firmly in a cylindrical percolator, and then add enough alcohol to saturate the drug and leave a stratum of liquid above it. When the, liquid begins to drop from the per- colator close the lower orifice and hav- ing closely covered the percolator, mac- erate for 48 hours. Then allow the percolation to proceed, gradually adding alcohol until 19 fluidounces of percolate are obtained or until the percolate ceases to produce more than a slight turbidity when dropped into water. Distil off the alcohol by means of a water bath until the percolate is reduced to the weight of 2 av. ounces, and add the latter, slowly, with constant stirring, to 23 fluidounces of water. When the pre- cipitate has subsided, decant the supei natant liquid, and wash the precipitate twice, by decantation, with fresh por- tions of hot water. After having drain- ed off all the liquid, transfer the resin to a porcelain dish and heat it to dry- ness on a water bath. — U. S. P. The U. S. P. requires jalap to yield not less than 8 per cent, of resin, but the root may yield a great deal more or a great deal less, and therefore the per- colation with alcohol should be con- tinued until the percolate gives scarcely any turbidity with water. Should the root contain much less than 8 p. c. of resin, as much as 19 fluidounces of per- colate need not be collected. II. Jalap, No. 40 powder av.oz. 8 Alcohol, distilled water, each sufficient Digest the drug with twice its weight of alcohol in a covered vessel, heating gently, for 24 hours, transfer to a per- colator, and when the liquid ceases to pass, continue percolation with alcohol until nothing more is dissolved. Add to the percolate obtained, 4 fluidounces of distilled water, remove the alcohol by distillation, transfer the residue while hot to an open dish, allow it to become cold, pour off the supernatant fluid from the resin, wash this 2 or 3 times with hot distilled water, and dry. — Brit. Pharm. III. Jalap, coarse powder av.oz. 8 Alcohol .' fl.oz. 54 Digest the jalap with 36 fluidounces of alcohol at a temperature of 35 to 40 deg. C. for 24 hours, agitating occa- sionally, express, digest the residue with the remainder of the alcohol as before, and again express. Mix the two liquids, filter, distil or evaporate off the alcohol, wash the residue with warm water until the washings are colorless, and dry the resin on a water bath, stirring con- stantly. — Germ. Pharm. 3*» AXDARD FORMULARY OF Resin of Podophyllum. (Podophyllin — Resin of Mayapple or Man- drake.) I. Podophyllum root, No. 60 powder av.oz. 16 Hydrochloric acid, U. S. P.fl.dr. 1% Alcohol, water, each sufficient Moisten the drug with 7 l / 2 fluidounces of alcohol, pack it firmly in a cylindrical percolator, and add enough alcohol to saturate the powder and leave a stratum of liquid above it. When the liquid be- gins to drop from the percolator, close the lower orifice, and, having closely covered the percolator, macerate for 48 hours. Then allow the percolation to proceed, gradually adding alcohol, until 25 fluidounces of percolate are obtained, or until the percolate ceases to produce more than a slight turbidity when drop- ped into water. Distil off the alcohol by means of a water bath, until the per- colate is reduced to the consistence of thin syrup, and pour it slowly, with constant stirring, into 16 fluidounces of water, previously cooled to a tempera- ture below 10 deg. C. and mixed with the acid. When the precipitate has sub- sided, decant the supernatant liquid, and wash the precipitate twice, by decanta- tion, with fresh portions of cold water. Spread it, in a thin layer, upon a strain- er, and dry the resin by exposure to the air in a cool place, protected from light. Should it coalesce during the drying, or aggregate into lumps having a varnish-like surface, it should be re- moved, broken in pieces, and rubbed in a mortar. As this is liable to happen during warm weather, the preparation is best made in cold weather. — U. S. P. Owing to its being a powerful irritant, great care must be exercised not to get any of this resin into the eyes. II. Podophyllum, No. 40 powder av.oz. 16 Alcohol fl.oz. 58 or sufficient Distilled water, hydrochloric acid, each sufficient Exhaust the drug with the alcohol by percolation, and recover the greater por- tion of the alcohol from the percolate by distillation. Pour the residue slowly, with constant stirring, into 3 times its volume of distilled water, previously acidulated with 1/24 its bulk of hydr- chloric acid. Allow the mixture to stand for 24 hours, wash the resin on a filter with distilled water, and dry at a temperature not exceeding 38 deg. C. — Brit. Pharm. Resin of Scammony. I. Scammony (so-called "gum scammony") av.oz. 4 Alcohol, water, each sufficient Digest the scammony with successive portions of boiling alcohol until it is ex- hausted. Mix the tinctures, and reduce the mixture to a syrupy consistence by distilling off the alcohol. Then add the residue in a thin stream, with active stirring, to 10 fluidounces of water, separate the precipitate formed, wash it thoroughly with water, and dry it with a gentle heat. II. Scammony root, coarse powder av.oz. 8 Alcohol, distilled water, each sufficient Exhaust the drug with alcohol by per- colation, recover most of the alcohol from the percolate by distillation, slowly pour the residue into 3 times its vol- ume of distilled water, constantly stir- ring, allow the mixture to stand for 24 hours, wash the resin on a filter with distilled water, and dry on a water bath. —Brit. Pharm. Resinoids. See Concentrations. Sal Alembroth. Mercuric chlorid, Ammonium chlorid, each equal parts Mix well and make a fine powder. Salt, Carlsbad, Artificial. (Sal Caro- linum Factitium — Sal Therma- rum Carolinarum Factitim.) I. In a dry, amorphous (powder) form PHARMACEUTICAL PREPARATIONS. 3£9 (N. F. and Germ. Pharm.) — also known as German Cathartic Salt: Potassium sulfate parts I Sodium chlorid parts 9 Sodium bicarbonate parts 18 Sodium sulfate, dried parts 22 Triturate the ingredients, previously well dried, to a fine, uniform powder. The Germ. Pharm. directs a moderately fine powder. The dried sodium sulfate is prepared by slowly drying the crystalline salt until it has lost one-half of its weight. II. In a crystalline form (N. F.) : Potassium sulfate parts 2 Sodium chlorid parts 18 Sodium carbonate, clear cry- stal parts 61 Sodium sulfate, crystal parts 88 Distilled water parts 50 Dissolve the potassium sulfate and sodium chlorid in the water, and add this solution to the other two salts, pre- viously melted in a tared capsule and at a gentle heat in their own water of crystallization. Evaporate the mixture to about 180 parts, set it aside in a cool place, and stir frequently, so as to pre- vent the formation of large crystals, taking care, however, that none of the salt separate in a pulverulent form. Dis- tribute any remaining water of crystal- lization uniformly over the crystals, and dry the whole mixture sufficiently by ex- posure to air, so that it will retain its crystalline character. A solution of about 16 grains of the dry, or about 27 grains of the crystalline salt, in 6 fluidounces of distilled water, represents an equal volume of Carlsbad water (Sprudel) in its essential con- stituents. The salts employed in the preparation of the crystalline form must have been purified by recrystallization. For the latter, the Germ. Form, has a somewhat different formula, as follows : Sodium chlorid part 1 Sodium carbonate, crystal, .parts 2 Sodium sulfate parts 5 Water, hot parts 12 Dissolve the salts in the hot water, filter the solution, and evaporate the filtrate until a film begins to form on the. surface, then set it aside to crystal- lize. Separate the crystals from the mother liquid and transfer them (with- out washing them with water) to bot- tles. Reject the mother liquid. The resulting crystals are colorless, with a tendency to effloresce, and are soluble in i l / 2 parts of water. Salts, Effervescent. The effervescent salts or powders, for which formulas are here given, are most conveniently and efficiently dispensed in the form of fine powders, because in this condition they can be made extem- poraneously and with an assurance of their freshness and efficiency. The pop- ular demand, however, seems to be for granular effervescent salts, the prepara- tion of which requires certain modifica- tions of the formulas, important only in so far as they enable the dispenser to granulate the powder in a convenient and expeditious manner. Effervescent powders or salts are composed of the medicinal agent in ad- mixture with an alkaline bicarbonate, an organic acid, and sugar. The proportion of the medicinal agent is dependent upon its dose, that of the alkaline bicarbonate and of the organic acid is dependent upon their molecular relation to each other, while the proportion of sugar is dependent upon the quantity necessary as a sweetening agent and diluent. The sugar is now frequently omitted. The ingredients for making the fine pulverulent form of effervescent pow- ders are : The medicinal agent, sodium bicarbonate, tartaric acid and sugar, and it is necessary that these be well dried before mixing them. To make the granular form of effer- vescent salts the ingredients need not be dried, unless specially directed, and the ingredients are the same as for the pul- verulent form, with the single excep- tion that one-half the molecule of tar- taric acid is replaced by one-half a molecule of powdered citric acid. 330 STANDARD FORM ULARY OF In order to facilitate the manufacture of effervescent salts, the- revised Na- tional Formulary recognizes three new- preparations, viz. : saccharated citric acid, saccharated tartaric acid, and sac- charated sodium bicarbonate. Saccharated citric acid is prepared by mixing 5 av. ounces of citric acid with 3 av. ounces of sugar, each to be in very fine powder. Saccharated tartaric acid is prepared by mixing 6^4 av. ounces of tartaric acid with zVa av. ounces of sugar, each to be in very fine powder. Saccharated sodium bicarbonate is pre- pared by mixing 6 av. ounces of sodium bicarbonate with 2 av. ounces of sugar, each to be in very fine powder. The ingredients of these preparations should be intimately mixed, and should be preserved in well-stoppered bottles. The proportion of sugar in these sac- charates is so adjusted that when either of the acid saccharates is mixed with an equal weight of the alkaline saccharate, the acid and alkali are in molecular re- lation to each other, and, when dis- solved in water, will form the neutral tartrate and citrate of sodium respec- tively. With these three saccharates in stock, it becomes possible to make effervescent powders or salts quickly with any medi- cinal agent that may be prescribed, their use being exemplified by the following general formulas: I. Fine Powder: Medicinal agent, fine pow- der av.oz. 2 Saccharated sodium bicar- bonate av.oz. 19 Saccharated tartaric acid, .av.oz. 19 Triturate the ingredients until a uni- formly mixed powder is obtained. In order to insure permanence of the prod- uct, the ingredients should be well dried before mixing: II. Granular Salt: Medicinal agent, fine pow- der av.oz. 2 Saccharated sodium bicar- bonate av.oz. 19 Saccharated tartaric acid, .av.oz. 9^ Saccharated citric acid av.oz. g l / 2 Mix the ingredients (not dried) in a mortar, transfer them to an evaporating dish, and heat on a water bath, kept at 60 to 71 degrees C, under constant stir- ring with a wooden spatula, until dry and uniformly granular. The saccharated citric acid, being made from crystallized citric acid con- taining one molecule of water of cry- stallization, supplies the moisture neces- sary to cause the powder, when heated, to cake and adhere together. If the somewhat pasty mass is then stirred with the spatula, small granules are readily formed, and these become firm when completely dried. Another method of making the granu- lar effervescent salts is to add to either of the above mixtures just enough alco- hol to form a pasty mass, then rubbing this through a No. 20 porcelain colander, and drying the product in a drying rocm at a gentle heat. The powders should be well dried and powdered before use. The alcohol used should be just suffi- cient to form a pasty mass, as an excess would make the drying require a longer period of time, and at the same time w r ould prove a serious waste. The alcohol method of making effer- vescent salts is recognized by the U. S. P. and the first edition of the N. F., the heat method by the revised N. F. It is, of course, not always that the proportion of the ingredients is the same as in the above general formulas. There may, for example, be more or less of the medicinal agent, and it may be necessary to add an extra amount of sugar. It is not necessary, either, to use any of the saccharates mentioned, but instead the alkaline bicarbonate, acid, sugar and medicinal agent or agents may be employed. Throughout the process of making these "salts," contact with metals should be carefully avoided. The mixtures should always be pre- PHARMACEUTICAL PREPARATIONS. 331 served in well-stoppered, wide-mouthed bottles. The following formulas for efferves- cent salts are taken from standard works of reference. Salt, Effervescent, of Antipyrin. (Ef- fervescent Phenazone.) Antipyrin av.oz. i Sugar av.oz. 2 Citric acid av.oz. 2 Tartaric acid av.oz. 3 Sodium bicarbonate av.oz. sVa Use all in powder. Mix the antipyrin and two acids, and with this incorpor- ate the sodium bicarbonate and sugar previously mixed. Place in a enameled iron evaporating dish and apply heat sufficient to cause the mixture to as- sume a granular form, and separate into granules of a convenient size by means of a suitable sieve. Dry the granules at a temperature not exceeding 120 deg. F. — Brit. Form. Each heaping teaspoonful will con- tain about 7H gr. of antipyrin. Salt, Effervescent, of Citrated Caf- feine. Citrated caffeine av.oz. 1 Citric acid av.oz. 5 Tartaric acid av.oz. 7 l /i Sodium bicarbonate av.oz. 14^ The tartaric acid and sodium bicar- bonate should be well dried and tritu- rated to fine powder before use; the citric acid should be used in the form of unefHoresced crystals. Reduce the latter to powder and mix it intimately with the citrated caffeine and tartaric acid, then thoroughly incorporate the sodium bicarbonate. Place the mixed powders on a plate of glass or in a suitable dish, in an oven heated to be- tween 93 and 104* deg. C. When the mixture has acquired a moist consist- ence by the aid of careful manipulation with a wooden spatula, rub it through a No. 6 tinned-iron sieve and dry the granules at a temperature not exceeding 54 deg. C. . Keep the product in well-stoppered, bottles.— U. S. P. This is an entirely different process from that of the U. S. P. 1890. The preparation of the latter contained sugar and was granulated with alcohol. It was as follows: Caffeine av.oz. l /i Citric acid av.oz. Y^ Tartaric acid av.oz. 7^ Sodium bicarbonate av.oz 8^4 Sugar av.oz. 8M Granulate by means of alcohol as de- scribed under Salts, Effervescent. This mixture contains 2 per cent, of citrated caffeine, whereas that of the present U. S. P. contains 4 per cent. If desired, the caffeine and citric acid in this mix- ture may be increased to x /2 ounce each. If desired this mixture may be used and dispensed in powder form. Salt, Effervescent, of Caffeine Hy- drobromid. Caffeine hydrobromid av.oz. ^2 Sugar av.oz. 2% Citric avid av.oz. 2}4 Tartaric acid av.oz. 3 Sodium bicarbonate av.oz. S Z A Use all in powder. Mix the caffeine with the two acids, and incorporate with sodium bicarbonate and sugar previous- ly mixed. Place in an enameled-iron evaporating dish, and apply heat suffi- cient to cause the mixture to assume a granular form and then separate into granules of a convenient size by means of a suitable sieve. Dry the granules at a temperature not exceeding 120 deg. F. — Brit. Form. Each heaping teaspoonful contains about 4 gr. of caffeine hydrobromid. Salt, Effervescent (Artificial), Carls- bad. Artificial Carlsbad salt (in form of dry powder) av.oz. 4 l / 2 Saccharated sodium bicarbon- ate av.oz. ioJ4 Saccharated tartaric acid. . .av.oz. io l /i Mix the ingredients, previously well dried, and triturate them until a uni- form powder is obtained. If desired in the granular form, sub- stitute saccharated citric acid, not dried, for one-half of the saccharated tartaric acid, and prepare the granulated com- pound as directed under the general formula.-— N. F. 332 STANDARD FORMULARY OF A solution of about 90 gr. of this prep- aration in 6 fluidounces of distilled wa- ter represents an equal volume of Carls- bad water (Sprudel) in its essential constituents. The preparation of the Brit. Form, differs from this only in having 1 gr. of saccharin added to each 4 av.ounces of effervescent salt. Salt, Effervescent, of Iron Citrate. Iron pyrophosphate, soluble. av.oz. 2 Citric acid av.oz. 5 Sodium bicarbonate av.oz. 5 Sugar av.oz. 10 Triturate the iron salt to powder, add the other ingredients, mix thoroughly in a porcelain mortar, and gently heat the whole (with mortar) on a water bath, triturating constantly until a moist mass is formed, which agglutinates suf- ficiently so it may be passed through a sieve. Then dry and bottle the product in the usual manner. — Germ. Pharm. The above forms a white product; a 3-ellowish one may be prepared by sub- stitution of iron citrate for the pyro- phosphate as in the following: Iron citrate, soluble av.oz. 1 Sodium bicarbonate av.oz. 10 Tartaric acid av.oz. 7 Citric acid av.oz. 1 Sugar av.oz. 8 Alcohol av.oz. 7 Reduce the iron salt to very fine pow- der, add the other solids in fine powder, mix well, warm slightly in an evapora- ting dish, moisten with the alcohol, and sift drv, and bottle in the usual manner. — D. Properly speaking, the first "iron cit- rate" is not a citrate, but a pyrophos- phate. Salt, Effervescent, of Iron Citrate with. Magnesia (or Iron and Magnesium Citrate.) Iron citrate, soluble av.oz. 1 Magnesium carbonate av.oz. ^2 Sodium carbonate av.oz. 10 Tartaric acid av.oz. 8 Citric acid av.oz. 1 ^2 Sugar av.oz. 8 Alcohol fl.oz. 7 Prepare like the preceding.— D. Salt, Effervescent, of Iron and Quin- ine Citrate. Soluble citrate of iron and quinine gr. 71 Saccharated sodium bicar- bonate av.oz. 8 Saccharated tartaric acid. . .av.oz. 8 Mix the ingredients, previously well dried, and triturate them until a uni- form powder is obtained. If desired in the granular form, sac- charated citric acid may be substituted for one-half of the tartaric acid, then follow the rules of the general form- ula.— N. F. Ninety grains (or about a heaped tea- spoonful) of this preparation represent about 1 gr. of citrate of iron and qui- nine. Salt, Effervescent, of Iron Phos- phate. Iron phosphate, soluble, very fine powder gr. 172 Saccharated sodium bicar- bonate av.oz. 8 Saccharated tartaric acid, .av.oz. 8 Mix the ingredients, previously well dried, and triturate them until a uni- form powder is obtained. If desired in the granular form, fol- low the rules of the general formula, substituting saccharated citric acid for one-half the saccharated tartaric acid, heaping, etc. Ninety grains (about a heaped tea- spoonful) represent about 2 gr. of iron phosphate. Salt, Effervescent, of Lithium Cit- rate. Lithium citrate gr. 360 Citric acid av.oz. 2> l A Tartaric acid av.oz. 5 Sodium bicarbonate av.oz. g l A The tartaric acid and sodium bicar- bonate should be well dried and finely powdered before use ; the citric acid should be used in the form of unefflo- resced crystals. Powder the citric acid and mix it intimately with the lithium citrate and tartaric acid and then thor- oughly incorporate the sodium bicarbo- nate. Place the mixed powders on a plate of glass or in a suitable dish, in an PHARMACEUTICAL PREPARATIONS. 333 oven heated to between 93 and 104 deg. C. When the mixture, by the aid of careful manipulation with a wooden spatula, has acquired a moist consist- ence, rub it through a No. 6 tinned-iron sieve, and dry the granules at a tem- perature not exceeding 54 deg. C. — N. F. Keep the product in well-stoppered bottles. This is entirely different from the preparation of the U. S. P. 1890, which was made by triturating s l A av.ounces of citric acid with 3 av.ounces of pow- dered sugar, drying the mixture thor- oughly, incorporating with this 1 av. ounce of lithium carbonate and 4 av. ounces of sodium bicarbonate and an- other ounce of sugar. The product may be granulated if de- sired by either the heat or alcohol proc- ess, as described under Salts, Efferves- cent. The preparation of the Brit. Pharm. is made from i J /i av.ounces of lithium citrate, 5 av.ounces of citric acid, 7^4 av.ounces of tartaric acid and 14M2 av.- ounces of sodium bicarbonate. This mixture is to be granulated by means of heat like that of the present N. F. Salt, Effervescent, of Iron Pyrophos- phate. See Salt, Effervescent, of Iron Citrate. Salt, Effervescent (Artificial) Kissin- gen. Artificial Kissingen salt.. . . .av.oz. 7 Saccharated sodium bicar- bonate av.oz. 9 Saccharated tartaric acid av.oz. 9 Mix the ingredients, previously well dried, and triturate them until a uni- form powder is obtained. If desired in the granular form, fol- low the general formula by substituting saccharated citric acid, not dried, for one-half the saccharated tartaric acid, heating, etc., according to the general formula. — N. F. A solution of about 80 gr. of this preparation in 6 fluidounces of distilled water represents an equal volume of Kissingen water (Rackoczi springs)^ in its essential constituents. Salt, Effervescent, of Lithium Car- bonate. Lithium carbonate ....av.oz. 2 Sodium bicarbonate av.oz. 6 Tartaric acid av.oz. 4 Sugar av.oz. 8 Alcohol fl.oz. 9 Mix the solids, and moisten and sift in the regulation manner. Dry first at 20 deg. C, then increase the tempera- ture to 40 deg. C, until perfectly dry. — D. Salt, Effervescent, of Magnesium Citrate. Magnesium carbonate, pow- der av.oz. 2*A Citric acid av.oz. 11^ Sodium bicarbonate av.oz. 8 J /> Sugar 1 av.oz. 2 Alcohol, water, each sufficient Mix the magnesium carbonate with 7 l A av.ounces of citric acid and 1 fluid- ounce of water so as to form a thick paste. Dry this at a temperature not' exceeding 30 deg. C. and reduce to fine powder. Then mix this intimately with the sugar, sodium bicarbonate and the remainder of the citric acid, dampen with alcohol, and granulate as described under Salts, Effervescent.— U. S. P. 1890 and Germ. Pharm. This preparation may also be granu- lated by the heat process. The commercial brands of "efferves- cent citrate of magnesia" contain little or no magnesium citrate, but are com- posed mainly of magnesium or sodium sulfate. Such a preparation is designa- ted "English style" to distinguish it from the true citrate. The U. S. P. recog- nizes effervescent magnesium sulfate. See also Salt, Effervescent, of Sodium Sulfate; also Salt. Effervescent, of So- dium Citro-Tartratc for a suitable sub- stitute for magnesium citrate. Salt, Effervescent, of Magnesium Silfate. Magnesium sulfate av.oz. 20 Sodium bicarbonate av.oz. 16 Tartaric acid av.oz. %}/ 2 Citric acid av.oz. 5^ The sodium bicarbonate and tartaric l acid should be dried and rubbed to fine 334 STANDARD FORMULARY OF powder, the citric acid and salt should be used in the form of uneffloresced crystals. Dry the magnesium sulfate on a water bath until it ceases to lose weight, then after powdering the dry salt, mix it intimately with the citric acid, which has previously been pow- dered, and the tartaric acid and thor- oughly incorporate the sodium bicarbon- ate. Place the mixed powders on a plate of glass or in a suitable dish, in an oven heated to between 93 and 104 deg. C. When the mixture has acquired a moist consistence by the aid of careful manip- ulation with a wooden spatula, rub it through a No. 6 tinned-iron sieve and dry the granules at a temperature not exceeding 54 deg. C. Keep the product in well-stoppered bottles.— U. S. P. VIII. II. Magnesium sulfate, crystal. av.oz. 25 Sodium bicarbonate av.oz. 18 Tartaric acid av.oz. g l A Citric acid av.oz. 6 l A Sugar av.oz. 5% Dry the magnesium salt at a tempera- ture of about 55 deg. C, until it has lost nearly one-fourth (23 per cent.) of its weight; powder the product, and mix with the sugar and other ingredients, all in fine powder. Then granulate the mix- ture by the heat method, then dry gran- ules at a temperature not exceeding 55 deg. C. — Brit. Pharm. Salt, Effervescent, of Pepsin. Pepsin, pure, powder gr. 150 Citric acid av.oz. 5^4 Tartaric acid av.oz. 5 Sodium bicarbonate av.oz. 12^4 Sugar gr. 720 Make by the U. S. P. process, or it may be prepared by either of the N. F. processes. Salt, Effervescent, of Pepsin and Bis- muth. Pepsin, pure, powder , . .gr. 150 Bismuth and ammonium cit- rate gr. 150 Citric acid av.oz. sVa Tartaric acid av.oz. 4^ Sodium bicarbonate av.oz. 12^4 Sugar gr. 720 Prepare like the preceding. Salt, Effervescent, of Phenacetine with Caffeine. (Effervescent Phenacetine with Caffeine.) Phenacetine gr. 275 Caffeine citrate gr. 138 Sugar av.oz. 2.. gr. 30 Citric acid av.oz. 2 Tartaric acid av.oz. 3 Sodium bicarbonate av.oz. sVa Use all in powder, mix the phenace- tine, caffeine citrate and two acids, and incorporate with the sodium bicarbonate and sugar previously mixed. Place the mixture in an enameled-iron dish and apply a heat sufficient to cause the mix- ture to assume a granular form, and then separate into granules of conve- nient size by means of a suitable sieve. Dry the granules at a temperature not exceeding 120 deg. F. — Brit. Form. Each heaping teaspoonful contains about 5 grains of phenacetine and 2 l / 2 of caffeine citrate. Artificial Vichy salt av.oz. 4 Lithium citrate, very fine powder gr. 630 Saccharated sodium bicar- bonate av.oz. 10 Saccharated tartaric acid, .av.oz. 10 Mix the ingredients, previously well dried, and trituiate them until a uni- form powder is obtained. If desired in the granular form, follow the general formula by substituting sac- charated citric acid, not dried, for one- half the saccharated tartaric acid, heat- ing, etc., according to the general form- ula.— N. F. Ninety grains (or about a heaped tea- spoonful) of this preparation represent 14 gr. of artificial Vichy salt, and 5 gr. of lithium citrate. Salt, Health. (Sundheds Salt.) This is a formula which is used for this Scandinavian preparation: Sodium bicarbonate parts 14 Magnesium carbonate part 1 Oil-sugar of peppermint part 1 Salt, Kissingen, Artificial. (Sal Kis- singense Factitium.) Potassium chlorid gr. 42 Magnesium sulfate, anhy- drous (dried) gr. 145 Sodium bicarbonate gr. 265 Sodium chlorid av.oz. 2 PHARMACEUTICAL PREPARATIONS. 335 Triturate the ingredients, previously well dried, to a fine, uniform powder. — N. F. A solution of about 24 gr. of this preparation, in 6 fluidounces of distilled water, represents an equal volume of Kissingen water (Rakoczi spring) in its essential constituents. Salt, Vichy, Artificial. (Sal Vichy- anum Factitium.) Potassium carbonate part 1 Salt, Effervescent, of Potassium Bromid. Potassium bromid, very fine powder av.oz. 3 Saccharated sodium bicar- bonate av.oz. 12 Saccharated tartaric acid. . .av.oz. 12 Mix the ingredients, previously well dried, and triturate them until a uniform powder is obtained. If desired in the granular form, fol- low the general formula by substituting saccharated citric acid, not dried, for one-half the saccharated tartaric acid, heating, etc., according to the general formula. — N. F. - Ninety grains (or about a heaped tea- spoonful) of this preparation represent about 10 gr. of potassium bromid. Salt, Effervescent, of Potassium Bromid Compound. Prepare this like the preceding, adding 131 gr. of caffeine (alkaloid) to the above mixture. — N. F. Ninety grains (about a heaped tea- spoonful) represent about 10 gr. of po- tassium bromid and 1 gr. of caffeine. Salt, Effervescent, of Potassium Cit- rate. Potassium citrate av.oz. 8 Citric acid av.oz. 6 l / 2 Tartaric acid av.oz. 10 Sodium bicarbonate av.oz. 19 The sodium bicarbonate and tartaric acid should be dried and rubbed to fine powder before use, the citric acid should be used in the form of uneffioresced crystals. Dry the potassium citrate on a water bath until it ceases to lose weight, then powder the salt, mix it in- timately with the powdered citric acid and the tartaric acid, and then thor- oughly incorporate the sodium bicarbon- ate. Place the mixed powders on a plate of glass or in a suitable dish in an oven heated to between 93 and 104 deg. C. When the mixture, by the aid of careful manipulation with a wooden spatula, has acquired a moist consist- ence, rub it through a No. 6 tinned-iron sieve, and dry the granules at a tempera- ture not exceeding 54 deg. C. — U. S. P. Keep the product in well-stoppered bottles. Salt, Effervescent, of Sodium Citro- Tartrate. Sodium bicarbonate av.oz. S z / 2 Tartaric . acid av.oz. 4*/ 2 Citric acid .av.oz. 3 Sugar av.oz. 2y 2 Prepare according to the general form- ula. The mixture is to be heated to a temperature of between 95 and 105 deg. C. and dried at a temperature not ex-, ceeding 55 deg. C. — Brit. Pharm. Salt, Effervescent, of Sodium Phos- phate. I. By the U. S. P. process, this is perpared exactly like effervescent salt of potassium citrate, using 8 av.ounces of exsiccated sodium phosphate in fine pow- der in place of the potassium citrate. II. Sodium phosphate, crystal, .av.oz. 12J/2 Sodium bicarbonate av.oz. i2 l A Tartaric acid av.oz. 6^4 Citric acid av.oz. 4 l / 2 Dry the sodium phosphate until it has lost 60 per cent, of its weight, then pow- der, add the other ingredients, and com- plete the process as according to the preceding formula. — Brit. Pharm. The preparations of the market con- tain sugar, while the above do not. A saccharine preparation may be made from 4^4 av.ounces of dried sodium phosphate and 15^ av.ounces each of sacchared sodium bicarbonate and sac- charated tartaric acid, and granulate with alcohol. Or substitute saccharated citric acid for one-half the tartaric acid and granulate by the heat method. 336 STANDARD FORMULARY OF Salt, Effervescent, of Sodium Sulfate. Sodium sulfate, clear crys- tals av.oz. 12^ Sodium bicarbonate av.oz. 12^4 Tartaric acid av.oz. 6^4 Citric acid av.oz. 4^ Dry the sodium sulfate until it has lost rather more than one-half (56 per cent.) of its weight, then add the other ingredients, and prepare the salt ac- cording to the preceding formula. — Brit. Pharm. Salt, Effervescent (Artificial), Vichy. Artificial Vichy salt av.oz. 6 Saccharated sodium bicar- bonate av.oz. gY2 Saccharated tartaric acid. . .av.oz. 9^2 Mix the ingredients, previously well dried, and triturate them until a uni- form powder is obtained. If desired in the granular form, follow the general formula by substituting sac- charated citric acid, not dried, for one- half the saccharated tartaric acid, heat- ing, etc., according to the general form- ula.— N. F. A solution of about 57 gr. of this preparation in 6 fluidounces of water represents an equal volume of Vichy water (Grande Grille spring) in its es- sential constituents. Salt, Effervescent (Artificial), Vichy, with Lithium. Magnesium sulfate, anhy- drous (dried) part 1 Sodium chlorid parts 2 Sodium bicarbonate parts 22 Triturate the ingredients, previously well dried, to a fine, uniform powder. — N. F. A solution of about 14 gr. of this preparation, in 6 fluidounces of distilled water, represents an equal volume of Vichy (Grande Grille spring) in its es- sential constituents. Salts, Volatile. Thomsonian (from the Guide and the Materia Medica) : Crude sal ammoniac oz. 1 Pearlash oz. 2 Reduce each by itself and then mix. This is therefore a crude form of ammonium carbonate. It was used for inhalation for headaches and was also therefore a crude form of our present "smelling salts." Salve Mulls. See Mulls, Plaster and Salve. Silica. (Silicea.) The process of Hahnemann is now superseded by the following better proc- ess of the British Homeopathic Pharma- copeia : Silica, powder part 1 Sodium carbonate, pure, dried parts 4 Fuse the carbonate in a capacious clay crucible, then gradually add the silica. When the evolution of gas ceases, pour the fused mass upon a clean marble slab. While still warm, pulverize it in a mortar ; put into a wide-mouthed bot- tle with enough distilled water to dis- solve it ; stopper the bottle and cap with wet bladder. The next day dilute the solution somewhat and filter through ab- sorbent cotton. Add to the filtered liq- uid, from time to time, small quantities of pure hydrochloric acid. The hydra- ted silica will be thrown down as a bulky, gelatinous, white precipitate. Col- lect this and wash on a strainer with distilled water until the washings are tasteless and show only a faint cloudi- ness when mixed with solution of silver nitrate. Finally dry upon a porcelain water bath. This makes a pure silica suitable for homeopathic use. It is used in the form of a trituration. See Triturations, Ho- meopathic. Silk Ligature, Carbolated. I. Lister's process : White wax gr. 45 Carbolic acid, crystal av.oz. 1 Silk thread, strong (not dyed) sufficient Mix the acid and wax by fusion, place into the mixture as much of the thread as may be desired and allow it to re- main until the mixture is cold. Then wipe off the excess of liquid from the thread by means of a cloth, and then PHARMACEUTICAL PREPARATIONS. 337 preserve the medicated fiber in a mix- ture of Carbolic acid, crystal gr. 50 Glycerin fl.dr. 6 Alcohol fl.dr. 10 — D. II. Czerny's process : Boil strong or thick silk thread (un- colored) in 5 per cent, carbolic acid water, for from 10 minutes to 1Y2 hours, according to the thickness of the thread. At the end of every half hour of boil- ing the carbolized water should be re- newed. The thread should be preserved in 2 per cent, carbolic acid water. — D. Silk Ligature, Iodoform. Partsch's process : Wind strong silk thread (uncolored) upon a glass spool, or other similar suit- able object, and macerate for 2 days in a 10 per cent, solution of iodoform in stronger ether (1 dr. idoform in 13 fluid- drams of stronger ether). Then dry the thread by exposing for a moment to the atmosphere, and preserve in well-closed glass bottles or jars. — D. Silk Ligature, Mercuric Chlorid. (Sublimated Silk Ligature.) I. Macerate strong uncolored silk thread for 24 hours in a 1 per cent, solution of mercuric chlorid in distilled water, then preserve in a solution of Mercuric chlorid gr. 1 Glycerin fl.dr. 3 Alcohol fl.oz. aVa — D. II. Schede-Kuemmell's process: Boil strong uncolored silk for 2 hours in a 1 per cent, aqueous solution of mer- curic chlorid, and preserve in a one- tenth aqueous solution of the same agent. — D. Silk Protective, Carbolated. (Carbo- lated Protective Oiled Silk.) Dextrin av.oz. Y2. Starch av.oz. 1 Distilled water fl.oz. 7^ Carbolic acid, crystal av.oz. Y* Heat the starch and dextrin with the water until the starch granules are bro- ken up, allow to cool, incorporate the acid, and paint this liquid with a broad soft brush on silk protective (which is commercially available). — D. Snuff, Catarrh. (Anticatarrhal Pow- der — Catarrh Powder — Pulvis Sternutatorius — Anticatarrhalis — Ferrier's Snuff — Compound Powder of Bismuth.) Morphine hydrochlorid gr. 1 Acacia, fine powder gr. 60 Bismuth subnitrate gr. 180 Mix them intimately by trituation. This snuff was devised by Dr. Ferrier in 1876. Snuff, Menthol. (Mentholin.) Menthol gr. 45 Boric acid gr. 90 Sugar > av.oz. Y* Sugar of milk av.oz. 1 Coffee, roasted av.oz. 1Y2. All should be in fine powder and be well mixed. — H. Snuff, Schneeberger. (Pulvis Sternu- tatorius Albus.) Various formulas have been used for making this preparation, the following being the most acceptable : I. Orris root av.oz. 1 Bayberry bark av.oz. 1 White hellebore av.oz. 2 Starch av.oz. 12 Oil of clove drops 20 The first four ingredients should be in the finest powder and the whole should be well mixed. II. White hellebore av.oz. ^4 Canada snake root av.oz. 1 Orris root av.oz. 1 Yz Rice powder av.oz. 5 Oil of bergamot drops 30 The first four ingredients should be in fine powder and all should be well mixed. — H. III. Canada snake root av.oz. 1 White hellebore av.oz. 1 Orris root av.oz. 3 Starch av.oz. 5 Oleobalsamic mixture drops 75 The first four ingredients should be in fine powder and all should be well mixed. — H. modified. 338 STANDARD FORMULARY OF Soap, Castile, White. (Soap or Sapo, U. S. P. — Hard Soap or Sapo Du- rus, Brit. Pharm. — Sapo Oleini- cus or Oleaceus — Oel Seife.) This is described by the U. S. P. as soap prepared from sodium hydrate and olive oil. The Brit. Phann. describes it as soap made with sodium hydrate and olive oil, and containing about 30 per cent, of water. The U. S. P. permits 36 per cent, of water. The nearest approach to the above in the Germ. Pharm. is the so-called "me- dicinal soap." See Soap, Medicinal. Soap, Curd. (Tallow or Animal Soap — Sapo Animalis.) According to the Brit. Pharm., in which this soap is largely used in prep- arations, this is soap made with sodium hydrate and a purified animal fat con- sisting principally of stearin (viz., tal- low), and containing about 30 per cent. of water. Soap, Pat. (Sapo Unguinosus— Mol- lin.) Potassa (caustic potash, pure) av.oz. V/ 2 Lard av.oz. 8 Glycerin av.oz. 3 Water sufficient Dissolve the potassa in enough water to make 6>2 fluidounces, heat the solu- tion, add the lard, stir well during one- half hour, add the alcohol, and maintain a temperature of 50 to 60 deg. C. for 12 hours ; then incorporate the glycerin. — Germ. Form, modified. Soap, Surgical. (Surgeon's Liquid Soap or Solution of Soap.) Improvements have been made in soaps or saponaceous liquids for ster- ilizing the field of operations as well as the hands of the surgeon and his as- sistants. These mixtures may also be used for cleansing the hands at any time, being excellent to remove odors. Addi- tion of alcohol or ether to such mixtures not only aids the detergent action of the soap but carries it more deeply into the pores of the skin. The following are good formulas : I. Oleic acid fl.oz. 5H Potassa (pure caustic potash), Distilled water, each sufficient Alcohol fl.oz. 2 x / 2 Stronger ether, to make fl.oz. 16 Dissolve 570 grains of the potassa in enough distilled water to make 10 fluid- drams. Mix the oleic acid with the al- cohol in a flask and drop in the potassa solution gradually (about 9 fluidrams be- ing required), agitating occasionally un- til a neutral soap solution is obtained, using phenolphthalein as indicator. Then add 10 minims more of the potassa solution so that the liquid is just alka- line. Allow the liquid to cool, and add the ether. Set aside for some time, if desired, and decant the liquid from the slight precipitate which usually forms. The mixture may be flavored with 15 to 40 minims of oil of lavender flowers or about 75 minims of terebene. The product contains approximately 40 per cent, each of potassium oleate and ether, 16 of alcohol and 4 of water. II. A mixture of equal parts of tinc- ture of green soap and ether may be used for the same purpose. III. Green (soft) soap av.oz. 6 Water fl.oz. 2 Glycerin fl.oz. 2 Alcohol fl.oz. 2 Oil of rose geranium, winter- green, bergamot, or pep- permint sufficient to flavor The oil should be dissolved in the alcohol before adding to the other in- gredients. Soap, Green or Soft. (Sapo Mollis, U. S. P. 1900 — Sapo Viridis, U. S. P. 1880— Sapo Kalinus, Germ. Pharm. — Potassa Soap — Kali or Schmier Seife.) I. Linseed oil, raw av.oz. 8 l / 2 Potassium hydroxid (caustic potash) av.oz. 2 Alcohol fl.dr. 6 l / 2 Water fl.oz. 9 Heat the oil in a deep, capacious ves- sel on a water or steam bath to a tem- perature of about 70 deg. C. Also dis- solve the potassa in the water, warm the PHARMACEUTICAL PREPARATIONS. 339 solution to about 70 deg. C, add to this the warm oil, and mix thoroughly. Then incorporate the alcohol and continue the heat (without stirring) until a small portion of the mixture is found to be soluble in boiling water without the oeparation of oily drops. Now allow the mixture to cool and transfer into suit- able vessels. — U. S. P. The potassium hydroxid used in this process should be of the strength desig- nated by the U. S. P., viz., 85 per cent. Potassa of any other strength, however, may be used if a proportionately larger or smaller quantity be taken. II. The following process was rec- ommended by the A. Ph. A. committee several years ago: Olive oil fl.oz. 16 Potassa av.oz. 6 Water sufficient Dissolve 5 av.ounces of potassa in 2> 2 fluidounces of water, and add 8 fluid- ounces of this solution to the oil con- tained in a suitable vessel, place this over a moderate fire, stirring until the mix- ture has thickened sufficiently. Gradu- ally add the remaining solution of po- tassa and continue the heat with occa- sional stirring until the mixture assumes a gelatinous condition. Dissolve the re- maining 1 av.ounce of potassa in 16 fluidounces of water, add this to the gelatinous mass, and evaporate the whole to proper consistency. Soft soap may be prepared from other fixed oils, such as cottonseed oil, but linseed oil and pure olive oil are usu- ally preferred. Linseed oil makes a brown soap, olive oil a pale yellow. III. Linseed oil av.oz. 10 Potassa av.oz. 2 Alcohol " fl.dr. g]/ A Water sufficient Dissolve the potassa in enough water to make iiY 2 fluidounces of solution. Warm the oil in a porcelain capsule and to it gradually add the alkaline liquid previously mixed with the alcohol. Heat the mixture on a water bath until saponi- fication is completed. — Germ. Pharm. 22 Soap, Jalap. (Sapo Jalapinus — Mass of Jelap Resin.) Resin of jalap, fine powder, Medicinal soap equal parts of each by weight Mix thoroughly. — Gerni. Pharm. The preparation of the former Germ. Pharm. was as follows : Resin of jalap av.oz. 1 Medicinal soap av.oz. 1 Alcohol fl.dr. 14 Water fl.dr. 4 Dissolve the mixed resin and soap in the mixed alcohol and water on a water bath, and then evaporate with constant stirring to a weight of 2% av.ounces. Soap, Medicinal. (Sapo Medicatus or Medicinalis.) Lard av.oz. 4 Olive oil av.oz. 4 Caustic soda gr. 630 Salt av.oz. 2 Sodium carbonate gr. 105 Alcohol .fl.dr. 9 Water sufficient Dissolve the soda in 9 fluidounces of water, heat the solution on a water bath, add to it gradually the lard and oil pre- viously melted together, and then con- tinue heating for another half hour, fre- quently agitating. Now add the alcohol and when the mass has become homo- geneous, gradually add 15^2 fluidounces of water. Heat again, adding, if neces- sary, from time to time, small quantities of solution of soda made as before (70 grains of caustic soda in 1 fluidounce of water), until a transparent soap is ob- tained which is soluble in hot water without separation of fat. To this mass add a filtered solution of the salt and sodium carbonate in 6K fluidounces of water and heat the whole with constant stirring until the soap has separated completely from the liquid. Allow to cool, remove the soap from the liquid, wash it with a small amount of water, then express it carefully yet completely, cut the soap into pieces and dry in a warm place. Powder before using. — Germ. Pharm. The caustic soda should be the puri- fied variety containing 90 per cent, of sodium hydrate. ?A0 STANDARD FORMULARY OF Soda with Lime. (London Paste — Soda Cum Calce.) Caustic soda, lime, each, .equal parts Reduce them to powder in a clean iron mortar, previously warmed, and mix them intimately. Keep the powder in small, well-stop- pered vials. Sodium Arsenate, Exsiccated. Take any convenient quantity of so- dium arsenate in crystals, break the lat- ter up into small fragments, and allow these to effloresce at a temperature be- tween 40 and 50 deg. C. until they are completely disintegrated; then gradually increase the temperature to 150 deg. C. and continue the drying until the prod- uct ceases to lose weight. Reduce it to fine powder and transfer it to dry, well- stoppered bottles. — U. S. P. Sodium. Boro-Benzoate. Sodium borate, fine powder, .parts 3 Sodium benzoate parts 4 Mix intimately. Sodium Carbonate, Dried or Exsic- cated. (Natrium Carbonicum Sic- cum.) Sodium carbonate, c. p., clear crystals av.oz. 16 Break the crystals into small frag- ments, allow them to effloresce for sev- eral days in warm air, at a temperature not exceeding 25 deg. C, until they are completely disintegrated, then dry the white powder at a temperature of about 45 deg. C. until its weight is reduced to 8 av. ounces. Pass the powder through a rather fine sieve, and preserve in well- stoppered bottles.— N. F. III., U. S. P. 1890 and Germ. Phaim. According to the Brit. Pharm., sodium carbonate is to be dried until it has "lost nearly 63 per cent, of its weight. Sodium Phosphate, Dried or Exsic- cated. Take any convenient quantity of so- dium phosphate in crystals, allow it to effloresce for several days in warm air at a temperature of from 25 to 30 deg. C, men continue the drying in an oven. Raise the temperature very gradually up to 100 deg. C. and maintain this tem- perature until the salt ceases to lose weight. Powder and sift the residue, and preserve it in well-stoppered bot- tles.— U. S. P. Sodium phosphate in clear crystals contains 60 per cent, of water of crys- tallization, therefore the dried salt is 2Y2 times as strong as the crystals. Sodium Sulfate, Dried or Exsiccated. (Natrium Sulfuricum Siccum.) Prepare like dried sodium carbonate. See Sodium Carbonate, Dried. — Germ. Pharm. Solutions. (Liquores.) The solutions differ from the other pharmaceutical preparations in being as a rule of inorganic origin. The solvent is generpHv water. For remarks on homeopathic solutions, see Solutions, Homeopathic. Solution of Acetic Acid. Glacial acid av.oz. 1 Distilled water fl.oz. 8. .fl.dn 5 — Homeopathic. This is a ix solution. Dilutions are made with distilled water, to be freshly made, for immediate use only. See Di- lutions, Homeopathic. Solution of Albuminate of Iron. See Solution of Iron Albuminate. Solution of Aloes and Soda, Met- tauer's. (Mettauer's Laxative Aperient.) Socotrine aloes gr. 300 Sodium bicarbonate av.oz. i l / 2 Comp. tinct. of lavender. . .fl. dr. 6 Water fl.oz. 16 Macerate for 2 weeks, agitating oc- casionally, and filter. Solution of Aluminum Acetate^ (Burow's Solution.) Aluminum sulfate, crystal- lized av.oz. 5 Acetic acid, 36 per cent. . . .av.oz. 5 Calcium carbonate (precipi- tated chalk) av.oz. 2 Water fl.oz. 14^ Dissolve the calcium carbonate in the acid mixed with 3^ fluidounces of wa- ter, and the aluminum sulfate in 11 fluidounces. Mix the two solutions, and PHARMACEUTICAL PREPARATIONS. 3-A1 allow the mixture to stand for 24 hours, agitating occasionally. Then pour off the clear solution and filter. — N. F. and Germ. Pharm. The directions of the Germ. Pharm. differ from the above only in directing the precipitated calcium sulfate to be expressed, without subsequent washing, in a thick linen cloth, and filtering the colature. The solution contains from 7.5 to 8 per cent, of basic aluminum acetate. II. Burow's formula : Aluminum sulfate, pure av.oz. 3 Lead acetate, pure, clear crys- tals av.oz. 5 Distilled water sufficient Dissolve the aluminum salt in 24 fluid- ounces of water and the lead acetate in i4 l / 2 fluidounces of water. Cool both solutions to 100 deg. C., then pour the lead solution gradually into the alumi- num solution, stirring constantly mean- while, and set aside in a cool place for 3 or 4 days, then filter. — D. III. The formula given under Solu- tion of Aluminum and Sodium Acetates is also largely employed instead of either of the above. Solution of Aluminum Acetico-Tar- trate. Alum (U. S. P. or aluminum and potassium sulfate) . .av.oz. 15 Sodium carbonate, pure, crys- tal av.oz. 14 Glacial acetic acid (U. S. P.) av.oz. 3 Tartaric acid av.oz. 2. .gr. 300 Water, to make av.oz. 20 Dissolve the alum and the sodium carbonate each in 200 fluidounces of wa- ter, mix the solutions, and wash the precipitate with water, first' by decanta- tion, and afterwards on a strainer, until the washings run off tasteless. Allow the precipitate to drain and to shrink in volume by exposure on the strainer. Then transfer it to a tared capsule, add the two acids, and apply heat until solu- tion has been effected. Finally evapo- rate the liquid to a weight of 20 av.- ounces. The product contains about 50 per cent, of dry, so-called aluminum acetico- tartrate. The dry salt may be obtained by evap- orating the solution. — N. F. Solution of Aluminum and Sodium Acetate. (Burow's Solution.) Lead acetate, pure av.oz. 3 Alum av.oz. 2 Sodium sulfate gr. 160 Distilled water fl.oz. 24 Dissolve the lead acetate in 9 fluid- ounces of distilled water which has pre- viously been boiled and cooled. Dissolve the alum and sodium sulfate in 15 fluidounces of water, add the first solution to it, shake well, allow to stand for 24 hours, decant the clear superna- tant liquid, and filter. — Cine. Acad. Pharm. This formula is frequently slightly varied as follows : Lead acetate, pure av.oz. 4 Potassa alum av.oz. 2^2 Sodium sulfate, pure, crys- tal av.oz. % Distilled water fl.oz. 32 Dissolve the alum and sodium salt in one-half the water, the lead acetate in the other half, filter the solutions, if nec- essary, mix them, allow the precipitate to subside, and use the clear liquid. Solution of Ammonium Acetate. (Spirit of Mindererus.) I. Ammonium carbonate gr. 184 Diluted acetic acid fl.oz. 8 Add the ammonium carbonate gradu- ally to the acid, and stir until dissolved. The acid should be as cool as pos- sible, and it should be of the full strength specified by the U. S. P., viz., 6 p. c. of absolute acid. It should also be pure, as should be the ammonium carbonate. The latter should be from hard, translucent pieces, free from any white, pulverulent bicarbonate. This preparation should be freshly made as wanted for use. — U. S. P. The product is an aqueous solution of ammonium acetate, containing about 7 per cent, of the salt, together with small amounts of acetic and carbonic acids. The product is, however, unnecessari- 342 STANDARD FORMULARY OF ly acid, and is much more so than the same preparation of the U. S. P. 1880. 220 grains of ammonium carbonate would be a better proportion than 180 grains. See also No. II. II. Add sufficient ammonium carbonate gradually to diluted acetic acid until the latter is neutralized. The alternative process of the U. S. P. 1880 is the most convenient and is probably the one mostly largely used. It is as follows, modified to practical form : Dissolve 420 grains of ammonium car- bonate in enough distilled water to make 8 fluidounces and filter, also make a mixture of 2J/2 fluidounces of 36 p. c. acetic acid and 5^ fluidounces of dis- tilled water. Keep the liquids in sep- arate, well-stoppered bottles, and when the solution is wanted, mix them in equal volumes. — U. S. P. 1880. The above proportions are correct as determined by weight and measure. III.' Ammonium carbonate, pure, clear pieces gr. 365 Acetic acid, distilled water, each sufficient Dissolve the carbonate in 10 times its weight of distilled water, neutralize with acetic acid, and add enough distilled water to make 16 fluidounces. — Brit. Pharm. The Brit. Pharm. directs that the solu- tion be preserved in a green glass bottle. IV. Ammonia water, 10 p. c fl.oz. 5*4 Acetic acid, 36 p. c fl.oz. 5 Distilled water fl.oz. I Mix in a porcelain capsule, and boil for several minutes. When the liquid has become cold, neutralize with ammo- nia water, filter, and add sufficient wa- ter to bring the liquid to a sp. gr. of 1.032 to 1.034. — Germ. Pharm. V. Solution of ammonium ace- tate, U. S. P fl.oz. 1 Distilled water fl.oz. 6 This is called a 2x solution. — Homeo- oathic. Solution of Ammonia Acetate and Morphine. Solution of ammonium ace- tate, U. S. P fl.dr. 1 Morphine acetate gr. 8 Syrup of lemon, to make. .. .fl.oz. 1 — Eclectic. Solution of Ammonium Acetate, Con- centrated. Acetic acid, 36 p. c fl.oz. 8 Ammonium carbonate, water, each, to make fl.oz. 16 Neutralize the acetic acid with a suffi- cient quantity of ammonium carbonate, carefully avoiding an excess. Then add enough water to make the product meas- ure 16 fluidounces. The product is of about 3 times the strength of the official solution. It is not recommended to keep this solution on hand for the preparation of the official solution, as this is preferably made freshly when wanted for use. When it is, however, required, or deemed of advantage, to dispense the concen- trated solution, it is suggested that it be diluted with carbonic acid water ("soda water"), or be directed to be diluted with this at the time of administration. Solution of Ammonia, Anisated. Oil of anise fl.dr. 1 Alcohol fl.oz. 3 l A Ammonia water, 10 p. c fl.dr. 5*4 — Germ, and Austr. Pharms. Solution of Ammonium Benzoate. Such a preparation may be made as follows : Ammonium carbonate gr. 500 Benzoic acid gr. 1165 Distilled water, to make, .fl.oz. 16 Reduce the ammonium salt to powder, mix it and the acid in a capacious ves- sel, add the water, stir frequently until effervescence has ceased and solution is complete, and filter. Each fluidram contains 10 gr. of am- monium benzoate. Solution of Ammonium Citrate. Citric acid oz. 2 Ammonia water, Distilled water, each q. s. Dissolve the citric acid in 10 fluid PHARMACEUTICAL PREPARATIONS. 343 ounces of distilled water, add 3 fluid ounces ammonia water, then cautiously add more ammonia water until a neutral solution is obtained. Cool the solution and add sufficient distilled water to make the product measure 16 fluid ounces. — N. F. Solution of Ammonium Citrate, Stronger. Citric acid av.oz. g%. Stronger water of ammonia (U. S. P. or 28 p. c), wa- ter, each, to make fl.oz. 16 Neutralize the acid with the stronger water of ammonia, and add enough wa- ter to make 16 fluidounces. Two fluidounces of the solution may- be made rf desired from 510 gr. of citric acid and corresponding quantities of the other ingredients. The solution should be kept in bottles free from lead. Each fluidram contains about 40 gr. of ammonium citrate. This solution is apt to take up notable quantities of lead, if kept in bottles made of flint glass. The N. F. states that solution of am- monium citrate, Brit. Pharm., may be prepared from this by mixing 1 volume with 4 of water. This is an error; it should be 1 volume with 3^ of water. Solution of Ammonium Succinate. Succinic acid av.oz. I Distilled water, empyreumat- ic ammonium carbonate, each sufficient Dissolve the acid in 8 fluidounces of warm water, neutralize with the carbon- ate, set aside in a cool place for 24 hours, occasionally agitating, filter, and add enough distilled water to make 10 av.ounces. — Dan. and Norw. Pharms. The empyreumatic ammonium carbon- ate (ammonii carbonate pyroleosus) is made by mixing 3 parts by weight with 97 of ammonium carbonate, and tritu- rating together until reduced to powder and mixed intimately. Solution of Ammonium Valerianate. Ammonium valerianate. gr. 240 Borax, powder gr. 384 Ammonia water sufficient Distilled water, to make. .. .fl.oz. 16 Mix the ammonium valerianate with 2 fluidounces of distilled water and add ammonia water, drop by drop, until a clear and slightly alkaline solution is produced; then add 4 fluidounces of wa- ter and the borax, stir the whole well, and when all or almost all has dissolved, add enough water to make 16 fluid- ounces, and filter. This makes a tasteless and odorless preparation. Solution for Anesthesia by Infiltra- tion. (Schleich's.) The Schleich method of local anesthe- sia by infiltration consists in the injec- tion into the tissues of an aqueous solu- tion of cocaine muriate, morphine muri- ate, and sodium chlorid. The formula most generally used is one composed of ]/ 2 gr. of cocaine hydrochlorid, % gr. of morphine hydrochlorid, and 1 gr. of so- dium chlorid to 1 ounce of sterilized wa- ter. This can be made stronger or weaker by adding more or less of the cocaine. If it is desired to keep this solution for some time, a few drops of carbolic acid may be added. The fol- lowing formulas are used for the tablets for making solutions Nos. 1, 2 and 3 : Formula No. 1. Cocaine hydrochlorid gr. 3 Morphine hydrochlorid gr. 1/3 Sodium chlorid gr. 3 Formula No. 2: Cocaine hydrochlorid gr. 1 1/2 Morphine hydrochlorid gr. 1/3 Sodium chlorid gr. 3 Formula No. 3: Cocaine hydrochlorid gr. 1/6 Morphine hydrochlorid gr. 1/12 Sodium chlorid gr. 3 Different syringes have been devised for injecting the fluid, one having a ca- pacity of 2 or 3 drams being the most convenient. The needles should be of different lengths, and one or two of them curved. The ordinary hypodermic needle will answer the purpose in many cases. 344 STANDARD FORMULARY OF Solution of Antimony Chlorid. (Li- quid Butter of Antimony— Solu- tion of Terchlorid of Antimony- Liquor Stibii Muriatici or Chlo- rati.) Black snlfid of antimony, pure av.oz. 6H Hydrochloric acid fl.oz. 32 Place the antimony compound in a porcelain or enameled-iron dish, add the acid, apply to the mixture at first a gentle hea, which must be gradually in- creased, as the evolution of gas slack- ens, until the mixture boils. Continue boiling for 15 minutes, then remove the vessel from the fire, and filter the liquid through calico, returning that which passes through at first until a perfectly clear liquid is obtained. Concentrate this by evaporation to 16 fluidounces, and preserve in a glass-stoppered bottle. — Brit. Pharm. 1885. The acid , for the above may be the commercial variety, but should be of full strength, 32 per cent. Owing to the fact that most of the ''black antimony" of the market is very impure, great care should be exercised in the selection of a suitable article. This black antimony should be in fine powder. The boiling of the liquid should either be done under a good flue or in the open air, to avoid tainting the atmos- phere of the room with the disagree- ably odorous sulfuretted hydrogen gas. The above preparation is substantially that of the first Germ. Pharm. (not recognized in later editions). Solution, Antiseptic, Alkaline. ("Al- kaline Antiseptic") Potassium bicarbonate gr. 480 Sodium benzoate gr. 480 Sodium borate gr. 120 Thymol gr. 3 Eucalyptol m. 3 Oil of peppermint m. 6 Tincture of cudbear fl.dr. 4 Alcohol fl.oz. 2 Glycerin fl.oz. 8 Purified talc gr. 150 Distilled water, to make. . .fl.oz. 22 Dissolve the salts in 19 fluidounces, and the thymol, eucalyptol and oils in the alcohol. Mix the alcoholic solution with the glycerin and the tincture, add the solution of the salts and enough water to make 32 fluidounces. Add the talc and shake occasionally during a few days, if convenient, then filter, returning the first portions, until the filtrate passes brilliantly clear. — N. F. Solution, Antiseptic, Lister's. (Lis- ter's Antiseptic Fluid — Antisep- tic Solution, U. S. P. and Cine. Acad. Pharm. — Compound Solu- tion of Thymol — Liquor Antisep- ticus.) A number of formulas have been ad- vocated for this preparation. Among the best known are the following: I. Boric acid t gr. 145 Benzoic acid gr. 7 Thymol gr. 7 Eucalyptol m. 2 (or drops 3) Oil of wintergr'n.m. 2 (or drops 3) Oil of pepp'm't. . .m. 4 (or drops 6) Oil of thyme m. 1 (or drops 2) Alcohol fl.oz. 4 Purified talc gr. 150 Water, to make fl.oz. 16 Dissolve the boric acid in 11M2 fluid- ounces of water and the benzoic acid in 2^2 fluidounces of alcohol, and pour the aqueous solution into the alcoholic solu- tion. Then dissolve in a mortar the thymol in the eucalyptol and oils, thor- oughly incorporate the talc and add with constant trituration the solution first pre- pared. Allow the mixture to stand for 48 hours, agitating occasionally, filter, to the filtrate add ij4 fluidounces of alco- hol and enough water to make 16 fluid- ounces. — N. F. This formula mentions no w r ild indigo which is generally present in the solu- tion. II. Benzoic acid gr. 128 Boric acid gr. 96 Sodium bicarbonate gr. 64 Thymol gr. 24 Menthol gr. 16 Oil of wintergreen drops 20 Oil of eucalyptus drops 10 Tincture of wild indigo. .. .fl.dr. 1 Alcohol fl.oz. 6 l / 2 Distilled water, to make. . .fl.oz. 16 Dissolve the sodium bicarbonate and PHARMACEUTICAL PREPARATIONS. 345 boric acid in 5 fluidounces of water by the aid of heat. Dissolve the remaining ingredients in the alcohol. Add the first solution to the second and enough wa- ter to make 16 fluidounces, and filter if necessary.— Cine. Acad. Pharm. III. Benzoic acid gr. 64 Borax gr. 64 Boric acid gr. 128 Thymol gr. 20 Oil of eucalyptus drops 5 Oil of wintergreen drops 5 Oil of peppermint drops 3 Oil of thyme (white) drop 1 Fluid ext. of wild indigo, .drops 20 Alcohol fl.oz. _ 6 Distilled water sufficient Dissolve the two acids and borax by the aid of heat in 8 fluidounces of water, also dissolve the thymol and oils in the alcohol, mix the two solutions, agitating frequently during mixing, add the fluid extract, and then enough water to make 16 fluidounces; set aside for 24 hours, and filter through purified talcum. IV. Boric acid gr. 128 Thymol gr. 20 Eucalyptol drops 5 OH of wintergreen drops 5 • Oil of peppermint drops 3 Oil of thyme, white drop 1 Fluid extract of wild indigo, .m. 30 Alcohol fl.oz. 3 Distilled water, to make. . .fl.oz. 16 Dissolve the acid in some of the water, add the other ingredients to the alcohol, dissolve, mix the two solutions, add the remainder of the water, let stand for 24 hours, and filter through purified tal- cum. V. Boric acid gr. 128 Thymol gr. 16 Menthol gr. 16 Oil of eucalyptus drops 4 Oil of wintergreen drops 4 Oil of horsemint drops 4 Water fl.oz. 12 Alcohol fl.oz. 4 Caramel drops 1 or 2 Dissolve the boric acid in the water and the other ingredients in the alcohol, mix the solutions, let stand for a day or two, shaking frequently, and filter. Solution, Antiseptic, Setter's. Sodium bicarbonate gr. 240 Sodium borate gr. 240 Sodium benzoate gr. 10 Sodium salicylate gr. 10 Eucalyptol m. 5 Thymol . gr. 5 Menthol gr. 2^2 Oil of wintergreen drops 3 Glycerin fl.oz. 4% Alcohol fl.oz. 1 Distilled water, to make... pints 8 Dissolve the salt in 64 fluidounces of water by the aid of heat, also the euca- lyptol, thymol, menthol, and oil in the alcohol, mix the two solutions, add the glycerin and the remainder of the water, allow to stand for 24 hours, and filter. Solution, Antiseptic, Thiersch's. This is the formula generally used for this solution : Salicylic acid gr. 15 Boric acid gr. 90 Distilled water, recently boiled water fl.oz. 16 Solution, Antiseptic, Volkman's. (Volkman's Antiseptic Liquid.) Thymol gr. 60 Alcohol fl.oz. 2 Glycerin fl.oz. 2 Distilled water fl.oz. 12 Dissolve the thymol in the alcohol, add the glycerin, and lastly the water. Used as an antiseptic on wounds and dressings. See also Solution, Germicide, which is a similar preparation. Solution of Arsenic, Valangin's. This may be extemporized as follows : Solution of arsenous acid, U. S. P fl.oz. 1 Distilled water fl.oz. 1 fl.dr. 2% Solution of Arsenicum Album. (So- lution of Arsenous Oxid.) Arsenous acid, vitreous, pure, fine powder gr. J2> Alcohol fl.dr. 13 Distilled water, to make. . . .fl.oz. 16 Add the acid to 13 fluidounces of dis- tilled water contained in a flask, heat until the former is dissolved, filter, and add to the filtrate the alcohol and enough water to make 16 fluidounces. — Homeopathic. 346 STANDARD FORMULARY OF This is a ix solution. Dilutions are made from this with dispensing alcohol. See Dilutions, Homeopathic. Solution of Arsenous Acid. (Solu- tion of Arsenic Chlorid, TJ. S. P. 1870 — Hydrochloric Solution of Arsenic.) Arsenous acid gr. 70 Diluted hydrochloric acid gr. 350 Distilled water, to make, .av.oz. 16 Mix the hydrochloric acid with 4 av.- ounces of water in a tared porcelain dish, add the arsenous acid and boil the mixture until the latter is dissolved. Then add the remainder of the distilled water, and filter. — U. S. P. The product contains 1 per cent, by weight of arsenic trioxid. In the U. S. P. 1890, this preparation was made up to certain quantity by measure, viz., 73 gr. of arsenous acid, 6 fluidrams of diluted hydrochloric acid, and distilled water to make 16 fluid- ounces. Only the pure arsenous acid should be used for making this preparation, not the ordinary commercial kind in powder form. In the Brit. Pharm. this preparation is made from 73 grains of arsenous acid, 96 minims of hydrochloric acid, and enough water to make 16 fluidounces. Solution of Arsenic and Gold Brom- ide. See Solution of Gold and Arsenic Bromid. Solution of Arsenic and Gold Iodid. See Solution of Gold and Arsenic Iodid. Solution of Arsenous and Mercuric Iodids. (Donovan's Solution.) Arsenous iodid gr. 70 Red mercuric iodid gr. 70 Distilled water, to make. . .av.oz. 16 Rub the two iodids together in a mor- tar, add 2 l / 2 fluidounces of distilled water, and continue trituration until so- lution is effected. Filter the liquid and pass enough water through the filter to make the filtrate weigh 16 av.ounces. — U. S. P. The product contains 1 per cent, each by weight of arsenous and mercuric iodids. In the U. S. P. 1890 and the Brit. Pharm., this preparation is made up to a certain quantity by measure, viz., 73 grains each of arsenous and mercuric iodids and enough water to make 16 fluidounces. When this preparation becomes dark yellow or brown from liberated iodin, it may be decolorized by agitation with a small amount of metallic mercury or ar- senic. Solution of Atropine Sulfate. Atropine sulfate gr. 18 Salicylic acid gr. 2 l / 2 Distilled water, recently boil- ed and cooled fl.oz. 4 Dissolve the two solids in the water. —Brit. Pharm. One hundred and ten minims of solu- tion contain 1 gr. of atropine sulfate. Dose, J / 2 to 1 minim. Solution of Bismuth. (Liquid Bis- muth — Liquor Bismuthi — Solu- tion of Bismuth and Ammonium Citrate.) I. Glycerite of bismuth fl.oz. 2 Alcohol fl.oz. 2 Distilled water fl.oz. 12 Mix the glycerite of bismuth with the distilled water, then add the alcohol. Solution of bismuth may also be pre- pared in the following manner : Bismuth and ammonium cit- rate gr. 128 Alcohol fl.oz. 2 Glycerin fl.oz. 1 Water of ammonia (U. S. P., or 10 p. c), distilled water, each, to make fl.oz. 16 Dissolve the bismuth and ammonium citrate in 12 fluidounces of distilled water, and allow the solution to stand a short time. Should any insoluble mat- ter have deposited, pour off the clear liquid and add just enough water of ammonia to the residue to dissolve it, or to cause it to retain a faint odor of ammonia. Then filter the united liquids, add the alcohol, the glycerin, and enough distilled water to make 16 fluidounces. PHARMACEUTICAL PREPARATIONS. 34? This preparation should be freshly made when wanted for use. Each fluidram contains i gr. of bis- muth and ammonium citrate. — N. F. II. Bismuth subnitrate gr. 512 Potassium citrate gr. 512 Potassium carbonate, pure, dry gr. 148 Nitric acid, pure, 69 p. c. . .fl.dr. 6 J / 2 Ammonia water, 10 p. c, Distilled water, each sufficient Dissolve the bismuth subnitrate in the nitric acid diluted with an equal volume of distilled water; add distilled water, constantly sitrring, until the liquid is very faintly opalescent ; add the potas- sium citrate and carbonate dissolved in a small amount of distilled water; heat the liquid to boiling, allow to cool; col- lect the precipitate; wash it with dis- tilled water until free from nitrates ; gradually add ammonia water to the moist precipitate until it is just dis- solved, dilute with distilled water to make 16 fluidounces; finally filter. — Brit. Pharm. Each/ fluidram contains an amount of bismuth equivalent to about 3 gr. of bismuth oxid. III. The Brit. Form, recognizes a "concentrated solution of bismuth," pre- pared as follows : Bismuth subnitrate. .av.oz. 2 gr. 350 Sodium bicarbonate av.oz. 3^4 Citric acid av.oz. 2 Nitric acid fl.oz. 2 Solution of ammonium cit- rate fl.oz. 4. .fl.dr. 5 Ammonia water, 10 p. c, Distilled water, each, enough to make fl.oz. 20 Dissolve the bismuth subnitrate in the nitric acid mixed with an equal volume of water by the aid of a little heat, and after cooling, add a solution of the citric acid in 2^4 fluidounces of distilled water. Then add gradually with stirring a solution of the sodium bicarbonate in 2}£ fluidounces of water, and wash the precipitate by decantation with succes- sive portions of distilled water until the washings are free, from nitrates. Col- lect the precipitate, and after draining, dissolve it in 2 fluidounces and 3 fluidrams of ammonia water, using a little more ammonia water if necessary. To the solution add the solution of am- monium citrate and enough distilled water to make 20 fluidounces. This preparation is twice the strength of the preceding one. Solution of Bismuth and Ammonium Citrate. See Solution of Bismuth. Solution (Test) of Brazil Wood. Boil 50 gm. of finely cut Brazil wood with 100 cc. of water during y?. hour, from time to time replacing the water lost by evaporation. Allow the mixture to cool, strain, wash the contents of the strainer with water until 100 cc. of cola- ture are obtained, add 25 cc. of alcohol, and filter. This turns purplish-red with alkalies and yellow with acids. — U. S. P. Solution of Bromids of Gold and Ar- senic. See Solution of Gold and Arsenic Bromids. Solution of Bromin. (Smith's Solu- tion of Bromin.) Bromin gr. 360 Potassium bromid gr. 180 Water fl.oz. 3 Dissolve the potassium bromid in the water contained in a bottle, add the bromid, and shake the mixture until dis- solved. Keep the solution in glass-stoppered vials in a cool place. As bromin vapor is very injurious to the respiratory passages and destructive to balances, it is often preferable to take the contents of an original bottle of bro- min — weighing the bottle, both before opening it and after emptying it, in order to ascertain the exact weight of the bromin contained therein — and then to use a quantity of potassium bromid and of water proportionate to the quantities above given. — N. F. Solution of Calcium Acetate. (Solu- tion of Calcaria Acetica, Hahne- mann.) Boil clean oyster shells for one hour 348 STANDARD FORMULARY OF in pure water, break or crush to coarse powder in a wedgewood or porcelain mortar, dissolve in diluted acetic acid by the aid of heat until the acid is satur- ated, filter, and reduce to one-fifth its volume. The solution obtained will be of a deep yellow color which, after a time, precipitates a dark brown, mucil- aginous substance leaving a lighter col- ored liquid. To this lighter colored liquid add an equal quantity of dispens- ing alcohol. — Homeopathic. This preparation contains about 10 per cent, of acetate of lime, and hence may be considered a I x solution. Dilu- tions are made from this with dispens- ing alcohol. See Dilutions, Homeo- pathic. Solution of Calcium Chloride, Rade- macher's. (Liquor Calcii Chlo- ra ti — Liquor Calcariae Muriat- icse.) Calcium chlorid. pure av. oz. 6 l /+ Water fl.oz. 12 Dissolve and filter.— D. and H. Solution of Calcium Hydrate. (Solu- tion of Calcarea Caustic or Cal- carea Usta.) Fresh slaked lime gr. 7^4 Distilled water fl.oz. 16 Dissolve by agitation. This makes a 3 x solution. Dilutions are to be made from it by addition of distilled water. See Dilutions, Homeo- pathic. All preparations of this medicine should be freshly prepared and be kept in green or bohemian glass bottles. — Homeopathic. For solution of calcium hydrate or lime of other pharmacopeias, see Water Lime. Solution of Calcium Oxysulfuret. See Solution of Sulfurated Lime. Solution of Carbolic Acid. What is usually understood by "solu- tion of carbolic acid" is a 5 per cent. solution of carbolic acid in water, or about 7 fluidrams of liquefied carbolic acid with enough water to make 16 fluidounces. The Eclectic solution is made from 1 part of carbolic acid, 3 of oil of lemon, and loo of alcohol. Solution of Carbolate of Sodium. See Solution of Sodium Carbolate. Solution of Carmine. Carmine av.oz. 1 Ammonia water (U. S. P., or 10 p. c.) fl.oz. 5^2 Glycerin fl.oz. 5 l / 2 Water, to make fl.oz. I4>4 Triturate the carmine to a fine powder in a wedgewood mortar, gradually add the ammonia water, and afterwards the glycerin, under constant trituration. Transfer the mixture to a porcelain cap- sule, and heat it upon a water bath, con- stantly stirring, until the liquid is en- tirely free from ammoniacal odor. Then cool, and add enough water to make 14^ fluidounces. The best quality of carmine, known in commerce as "No. 40," should be used for this preparation. — N. F. Solution, Carter's. Zinc sulfate gr. 2 Boric acid gr. 20 Camphor water fl.dr. 4 Water, to make fl.oz. 4 For the eyes. — N. Y. Hospitals. Solution of Chlorin. Chlorin water, U. S. P. strength fl.oz. 1 Distilled water fl.oz. 3 — Homeopathic. This makes a 3 x solution from which dilutions are made by addition of dis- tilled water. See Dilutions, Homeo- pathic. Solution of Chlorinated Lime. (Li- quor Calcis Chlorinatse.) Chlorinated lime av.oz. 6^4 Distilled water gall. Vi Mix, transfer to a bottle, set aside for 3 hours, shaking occasionally, and strain through muslin. Preserve in a stoppered bottle in a cool, dark place. — Brit. Pharm. The solution should be capable of yielding, when fresh, about 3 per cent. of available chlorin. PHARMACEUTICAL PREPARATIONS. 349 Solution of Chlorinated Potassa. (Ja- velle Water — Eau de Javelle — Liquor Potassae Chloratae.) Potassium carbonate av.oz. 2 Chlorinated lime av.oz. 2^4 Water, to make fl.oz. 32 Mix the chlorinated lime, contained in a tared flask, with 12 fluidounces of water. Dissolve the potassium carbonate in 9 fluidounces of boiling water, and pour the hot solution into the mixture first prepared. Shake the flask well, stopper it, set it aside to cool, and then add enough water to make the contents weigh 34^ av. ounces. Allow the sus- pended matters to subside, and remove the clear solution by means of a siphon, or by straining through muslin. Keep the product in well-stoppered bottles. The chlorinated lime for this prepara- tion should not contain less than 25 per cent, of available chlorin. — N. F. Solution of Chlorinated Soda. (Liquor Sodse Chloratse or Chlorinatae — Labarraque's Solution — Liquor Natri Hypochlorosi.) Sodium* carbonate, mono- hydrated av.oz. 4^ Chlorinated lime av.oz. 6*4 Water, to make gall. l / 2 Triturate the chlorinated lime with 14 fluidounces of water, gradually added, until a uniform mixture results. Allow the heavier particles to subside, and transfer the thinner, supernatant por- tion to a filter. Then triturate the resi- due again with 14 fluidounces of water, transfer the whole to the filter, and when the liquid has drained off, wash the filter and contents with 7 fluidounces of water. Dissolve the sodium carbonate in 20 fluidounces of hot water, and add this solution to the previously obtained filtrate contained in a suitable vessel. Stir or shake the mixture thoroughly and if it should become gelatinous, warm the vessel until the contents liquefy. Then transfer the mixture to a new filter, and when no more liquid drains from it, wash the filter and contents with enough water to make the product measure Yz gallon. — U. S. P. The chlorinated lime used for this preparation should be capable of yield- ing at least 30 per cent, of available chlorin. The product should be kept in well- stoppered bottles protected from light, and in a cool place. This preparation is an aqueous solu- tion of several chlorin compounds of sodium, containing at least 2.4 p. c. by weight of available chlorin. The Brit. Pharm. directs 8 J /i av.ounces of chlorinated lime and i2 J / 2 of crystal sodium carbonate to l / 2 gallon of dis- tilled water. Solution of Chromic Acid. Chromic anhydrid (so-called "acid") « av.oz. 1 Distilled water fl.dr. 23 Or dissolve 152 grains of "acid" in 1 fluidounce of water. — Brit. Pharm. Solution of Coal Tar. (Liquor Picis Carbonis, an Imitation of Liquor Carbonis Detergens.) Soap bark, No. 20 powder. av.oz. 1^ Alcohol sufficient Prepared coal tar av.oz. 3 Extract the drug by percolation with the alcohol so as to obtain 14^ fluid- ounces of product ; to this add the tar, digest at a temperature of about 50 deg. C. for 2 days, agitating occasionally, allow to become cold, and decant the clear liquid or filter. — Brit. Pharm. Prepared coal tar (Pix carbonis prse- parata) is made by placing commercial tar in a shallow vessel, and heating to a temperature of 50 deg. C. for an hour, stirring frequently. Solutions, Concentrated. (Liquores Concentrati.) The present (1898) edition of the Brit. Pharm. recognizes a number of preparations known as "concentrated so- lutions" which are really decoctions or infusions in concentrated form, and are usually prepared by extracting the drug with a hydroalcoholic menstruum. They are 10 times the strength of the corres- ponding infusion except concentrated compound, solution of sarsaparilla which 350 STANDARD FORMULARY OF is 8 times the strength of the corres- ponding decoction. They are described under the head of the corresponding infusion or decoction. Solution of Conium. Inspissated juice of conium. .gr. 225 Tincture of tolu fl.oz. 4^ Madeira wine fl.oz. 6 Water fl.oz. 6 — Eclectic. Solution of Cresol, Compound. Cresol av.oz. 7V\ Linseed oil, raw av.oz. 6 Potassium hydroxid (caustic potash) av.oz. i l A Water, to make av.oz. 15J/2 Dissolve the potassa in 7 fluidounces of water in a tared dish, add the oil and mix thoroughly. Then add the cresol and stir until a clear solution is pro- duced and finally add the remainder of the water.— U. S. P. The product contains 50 per cent, by weight of cresol. The Germ. Pharm. recognizes a very similar preparation under the name Sa- ponated Solution of Cresol which is made by warming together equal parts by weight of crude cresol and soft (green) soap until a clear solution is obtained. See also a very similar preparation under Tincture of Cresol, Saponated. Solution of Crotalus. This is a Homeopathic preparation consisting of solution of 73 grains of drug in 16 fluidounces of glycerin. This makes a 2 x solution. See Solutions, Homeopathic. Dilutions are to be made from this so- lution with glycerin. See Dilutions, Homeopathic. The drug is the venom of the rattle- snake, procured by compressing the gland while the serpent is pinioned in a frame or is under the influence of chloroform. Solution of Cuprum Acetate. Copper acetate, pure gr. 73 Distilled water fl.oz. 16 — Homeopathic. This makes a 2 x solution, from which 3 x and higher are to be made with dis- tilled water. See Dilutions, Homeo- pathic. Preparations of copper acetate should be freshly made as required. Solution of Fehling's. (Alkaline Cupric Tartrate Volumetric Solu- tion — Solution of Potassio-Cup- ric Tartrate.) I. . The Copper Solution. — Dissolve 34.67 gm. of carefully selected, small crys- tals of pure copper sulfate, showing no efflorescence or of adhering moisture, in enough distilled water to make the solution measure, at 25 deg. C, exactly 500 cc— U. S. P. Keep this solution in small, well-stop- pered bottles. The Rochelle Salt or Alkaline 'Tar- trate Solution. — Dissolve 173 gm. of pure rochelle salt and 75 gm. of potassium hydrate (pure potassa of the U. S. P. containing 85 per cent, of absolute potas- sium hydrate) in enough distilled water to make the solution measure, at 25 deg. C, exactly 500 cc. Keep the solution in small, rubber- stoppered bottles. For use, mix exactly equal volumes of the two solutions at the time re- quired. II. No. 1 is made from 34.64 grams of copper sulfate in crystals, 0.5 cc. of sulfuric acid (58 p. c), and distilled water enough to make 500 cc. No. 2 is made from 176 grams of rochelle salt, 77 grams of sodium hy- drate, and distilled water enough to make 500 cc. Equal volumes of Nos. I and 2 are to be mixed at the time of using. — Brit. Pharm. Solution of Ferrum Acetate. This is to be prepared by making a fresh solution of 1 part of ferric acetate in 9 parts of distilled water. A solution of the same strength may be made by mixing 2 volumes of U, S. P. solution PHARMACEUTICAL PREPARATIONS. 351 of iron acetate with 5 of distilled water. — Homeopathic. This forms a I x solution, from which dilutions may be made by addition of distilled water as described under Dilu- tions, Homeopathic, which see. Solutions, Germicide. ("Germi- cide.") Thymol gr. 120 Oil of eucalyptus fl.oz. 1 Oil of lavender fl.oz. 1 Alcohol fl.oz. 12^4 Water, to make fl.oz. 16 Dissolve the thymol and oils in the alcohol, add the water and filter, if necessary. Solution of Gold and Arsenic Bro- mids. Arsenous acid gr. 18 Gold tribromid gr. 24 Bromin water, distilled water, each sufficient Introduce the arsenous acid and about 18 fluidrams of bromin water into a flask and heat gently until all free bro- min has disappeared. Then add bromin water, 20 to 30 drops at a time, until it will be present in slight excess, or until the solution does not become colorless after some time. Transfer the solution to a porcelain capsule, expel the excess of bromin with the aid of gentle heat, dilute it with water to about 10 fluid- ounces, and dissolve in this the gold tribromid, adding enough water to make 16 fluidounces. Ten minims of this solution contain 1/32 grain of gold tribromid and the equivalent of 1/13 grain of arsenic tri- bromid. — N. F. The quantity of gold tribromid re- quired for the above formula may be made by placing 11 grains of gold leaf into a flask containing s x A fluidounces of water and 115 grains of bromin, shak- ing the mixture until the gold is dis- solved, then boiling to expel excess of bromin. When cold this solution may be added to the solution of arsenic bro- mid, previously prepared, and the mix- ture adjusted with the water to the proper volume. Solution of Gold and Arsenic Iodid. Arsenous acid gr. 21 Iodin gr. 52 Gold triiodid gr. 24 Distilled water, to make. .. .fl.oz. 16 Introduce the arsenous acid and iodin into a flask, add about 8 fluidounces of water, and heat cautiously until the iodin is dissolved, being careful to avoid loss of iodin by volatilization. Dissolve the gold salt in this solution, then trans- fer to a porcelain capsule, and heat over a water bath until all the iodin is ex- pelled, cool and add enough distilled water to make 16 fluidounces. Ten minims of this solution contains 1/32 gr. gold triiodid and 1/32 gr. ar- senic pentoxid or equal to 1/8 gr. of arsenic triiodid. — Cine. Acad. Pharm. Gold triiodid may be prepared by dis- solving 30 grains of gold in a little nitro- hydrochloric acid to form chlorid. Then heat gently with 35 grains potassium iodid and 3 fluidrams of diluted sulfuric acid, allow to cool, shake out the gold triiodid with ether, decant the ethereal solution, and evaporate the latter spon- taneously. Solution of Gutta-Percha. (Trauma- ticin.) Gutta percha, thin slices. .. .av.oz. 1 Chloroform, commercial .fl.oz. 6*A Lead carbonate, fine powder. av.oz. 1 Add the gutta percha to 5 fluidounces of the chloroform, contained in a bottle, cork it well, and shake it occasionally until the gutta percha is dissolved. Then add the lead carbonate, previously mixed with the remainder of the chloroform, and, having several times shaken the whole together, at intervals of half an hour, set the mixture aside until the insoluble matters have subsided and the solution has become perfectly clear. Lastly, decant the liquid and preserve it in small, cork-stoppered vials. — N. F. and U. S. P. 1880. Purified gutta percha is now commer- cially available as so-called gutta percha tissue and may be used in place of the ordinary kind. A solution prepared from the purified article will not re- 352 STANDARD FORMULARY OF quire clarification by lead carbonate or other means. Solution, Homeopathic. Solutions used in homeopathic phar- macy are solutions of substances in water or in alcohol. Aqueous solutions are made of sub- stances which are soluble in water but not in alcohol, or those which., when soluble in alcohol, are subject to chemi- cal change or decomposition. These substances are to be dissolved in the proportion of i/io, i/ioo or i/iooo, de- pending on the degree of solubility. Aqueous solutions as a rule are unstable and will keep but a short time. Distilled water only should be used for homeo- pathic preparations. Alcoholic solutions (these are fre- quently but improperly called tinctures ; they should always be known as solu- tions) are made of substances which either wholly or in part yield their medicinal properties to alcohol. This applies to liquids like oil of turpentine and other oils. These are to be made on the decimal scale, that is, in the pro- portion of i part by weight of the medi- cinal substance to 10 parts by volume of alcohol, and hence equal to the first decimal dilution (i x). If the sub- stance is not soluble in the proportion of i to io, 4 i part by weight should be dissolved in ioo parts of alcohol, this making the second decimal dilution (2 X). If liquid acids are used or drugs con- taining water, this should be deducted from that contained in the solvent, and the anhydrous acid or drug taken as the unit of strength. For further remarks on alcoholic solu- tions, see Tinctures, Homeopathic. For method of indicating strength of dilutions, method of dilution or attenua- tion of liquids, etc., see Dilutions, Home- opathic. Owing to indiscriminate interchange of the terms solution and tincture, if a homeopathic solution be not founrl Jn this work under Solutions, then see un- der Tinctures. Solution of Hydrastine, Compound. (Compound Glycerite of Hydras- tine — "Colorless Fluid Extract of Hydrastis or Golden Seal.") I. Eccles' formula : Hydrastine hydrochlorid gr. 25 Aluminum chlorid gr. 23 Calcium chlorid gr. 20 Magnesium chlorid gr. 18 Potassium chlorid gr. ^ Diluted hydrochloric acid m. 10 Distilled water fl.oz. 6 Glycerin, to make fl.oz. 16 Dissolve the salts in the water, add the acid, then the glycerin, and filter. If the so-called hydrochlorid of alum- inum is used instead of the anhydrous chlorid, somewhat more than double the amount is needed. The above is based upon a chemical examination of the preparations of the market. a Hydrastis, fine powder av.oz. iy l / 2 Glycerin fl.oz. 8 Ether sufficient Diluted sulfuric acid fl.dr. 1 Distilled water fl.oz. 8 Exhaust the hydrastis with ether, re- cover the ether by distillation, to the residue add the water previously mixed with the acid, let stand 7 days, agitating frequently, decant the aqueous solution, and mix it with the glycerin. III. This formula is also used: Hydrastine hydrochlorid gr. 20 Glycerin fl.oz. 6 Distilled water fl.oz. 10 Mix, dissolve and filter. Solution of Hydriodic Acid. A 10 per cent, solution of hydriodic acid may be prepared as follows : Potassium iodid av.oz. 4^ Tartaric acid av.oz. 3^ Distilled water fl.oz. 16 Dissolve the solids separately, each in 8 fluidounces of the water, mix the solu- tions by thorough agitation, set aside in a cool place, preferably on ice, then de- cant the clear liquid, and filter. The syrup may be extemporized by PHARMACEUTICAL PREPARATIONS. 353 mixing I volume of the above with 9 volumes of simple syrup. Solution of Hydrochloric Acid. Acid. U. S. P. strength gr. 570 Distilled water, to make fl.oz. 4 — Homeopathic. This is a 1 x solution. Dilutions are made with distilled water, to be freshly made, for immediate use only. See Di- lutions, Homeopathic. Solution of Hypophosphites. Calcium hypophosphite gr. 256 Sodium hypophosphite gr. 145 Potassium hypophosphite ...gr. 128 Hypophosphorous acid, 30%. m. 45 Distilled water, to make. . .fl.oz. 16 Triturate the salts, add the acid, and dissolve them in the distilled water and filter.— N. F. Each fluidram contains 2 gr. of cal- cium hypophosphite, about i 1 /^ gr. of sodium hypophosphite and 1 gr. of po- tassium hypophosphite. Solution* of Hypophosphites, Com- pound. I. Calcium hypophosphite gr. 64 Potassium hypophosphite ....gr. 64 Ferric hypophosphite gr. 32 Sodium hypophosphite gr. 16 Manganese hypophosphite ...gr. 16 Quinine hypophosphite gr. 16 Strychnine (alkaloid) gr. ^2 Potassium citrate gr. 64 Hypophosphorous acid, 30%.. m. 45 Orange flower water fl.dr. 4 Glycerin fl.oz. 4 Distilled water, to make fl.oz. 16 Dissolve the calcium, sodium and po- tassium hypophosphites in 5 fluidounces of distilled water. Also dissolve the re- maining solids in 4 fluidounces of die- tilled water, adding the hypophosphorous acid. Mix the two solutions, add the orange flower water and glycerin, and enough distilled water to make 16 fluid- ounces. Allow the mixture to stand a day or two, if convenient, and filter. II. (Compound solution of iron hypo- " phosphite) : Calcium hypophosphite gr. 267 Sodium hypophosphite gr. 267 Magnesium hypophosphite. . .gr. 133 Solution of iron hypophos- phite, No. IV fl.oz. 5 Distilled water, to make. . .fl.oz. 16 Dissolve the three hypophosphites in 10 fluidounces of distilled water, add the solution of iron hypophosphite and the acid, filter, and add enough distilled water through the filter to make the product measure 16 fluidounces. — Brit. Pharm. Solution of Iodid of Arsenic and Gold. See Solution Gold and Arsenic Iodid. Solution of Iodin, Carbolized. (Boul- ton's Solution — French Mixture — Liquor Iodi Carbolatus.) Compound tincture of iodin. fl.dr. 2 Carbolic - acid, liquefied by gentle heat m. 40 Glycerin fl.oz. 2^ Water, to make fl.oz. 16 Mix the glycerin with the acid and tincture, add enough water to make 16 fluidounces and expose the mixture to sunlight until it has become colorless. — N. F. Solution of Iodin, Caustic. (Iodin Caustic — Churchill's Iodin Caus- tic.) Iodin av.oz. 1 Potassium iodid av.oz. 2 Water fl.dr. 30 Dissolve the potassium iodid and the iodin in the water. — N. F. Solution of Iodine, Caustic, LugoPs. Iodin gr. 455 Potassium iodid gr. 910 Water fl.oz. 2 Dissolve the potassium iodid in the water and add the iodin. This is for application as a caustic. — H. Solution of Iodin, Compound. (Lu- goPs Solution.) I. Iodin gr. 200 Potassium iodid gr. 400 Distilled water fl.oz. JV? Dissolve the iodin and potassium iodid in the water. — U. S. P. Keep the solution in glass-stoppered bottles. This is the solution that is to be dis- pensed when Lugol's solution of iodin is demanded. 354 STANDARD FORMULARY OF II. Iodin gr. 180 Potassium iodid gr. 360 Rose water fl.oz. 8 Distilled water may be substituted for the rose water. — Eclectic. Solution, Iodin, Magendie's. Iodin gr. 2 Potassium iodid gr. 240 Peppermint water fl.oz. 6 Dissolve the potassium iodid in the water and add the iodin. Solution of Iodin, Mild, Lugol's. Iodin gr. I Potassium iodid gr. 2 Distilled water fl.oz. 4^ This is used externally, for injection and for insuffation in coryza. — H. Solution of Iodin, Rubefacient, Lu- gol's. Iodin gr. 180 Potassium iodid gr. 360 Water fl.oz. 6 Dissolve the potassium iodid in the water and add the iodin. — H. Solution of Iron (Ferric), Acetate. I. Solution of iron (ferric) sulfate av.oz. 8 or fl.oz. sH Acetic acid, glacial, av.oz. 2, gr. 260 or fl.oz. 2, fl.dr. 3 Ammonia water fl.oz. 83^ Water, distilled water, each sufficient Mix the ammonia water with 30 fluid- ounces of cold water, and the iron solu- tion with 6 pints of cold water. Add the latter solution gradually, with con- stant stirring, to the ammoniacal liquid, let the mixture stand until the precipi- tate has subsided as far as practicable, and then decant the supernatant liquid. Add to the precipitate 6 pints of boiling water, mix well, and again set the mix- ture aside as before. Repeat the wash- ing with successive portions of boiling water, in the same manner until the washings are no longer affected by so- dium-cobaltic-nitrite test solution (show- ing the removal of ammonia and its salts). Transfer the mixture to a wet muslin strainer, allow the precipitate to drain completely, and press it, folded in the strainer, until it is reduced to a weight of 7 av.ounces or less. Now add the precipitate gradually to the glacial acid contained in a tared jar provided with a glass stopper, stirring the mix- ture after each addition until each por- tion added is nearly dissolved before adding another portion. Finally add enough distilled water to make the prod- uct weigh 10 av.ounces or measure 8*4 fluidounces, mix thoroughly, allow it to become clear by subsidence from stand- ing, and decant the clear liquid. The glacial acetic acid should contain at least 99 p. c. of absolute acid, the ammonia water should contain at least 10 p. c. of absolute ammonia : if weaker, proportionately more of it must be em- ployed. Keep the product in well-stoppered bottles, in a cool place, protected from light.— N. F. and U. S. P. 1890. The product is an aqueous solution of ferric acetate containing about 31 p. c. of the anhydrous salt, and corresponding to about 7.5 p. c. of metallic iron. The formula of the Brit. Pharm. is practically like the preceding. II. For the homeopathic solution, see Solution of Ferrum Acetate. Solution of Iron, Acid, Howe's. This is an eclectic preparation first advocated by Prof. Howe. It is as fol- lows : Ferrous sulfate, pure av.oz. 2 Nitric acid, pure fl.oz. 1 Distilled water fl.oz. 10 Triturate the ferrous sulfate to coarse powder, add the water and acid, and bottle when the liquid assumes a clear amber color. No heat is to be employed. Solution of Iron Albuminate. I. Egg albumen, dry gr. 565 Solution of iron oxychlorid. fl.oz. 4 Alcohol fl.dr. 29 Aromatic elixir fl.oz. 12 Solution of sodium hydrate, Distilled water, each, to make fl.oz. 31 Dissolve the albumen in 62 fluidounces PHARMACEUTICAL PREPARATIONS. 355 of distilled water, strain the solution through muslin, and add the iron solution previously diluted with 62 fluidounces of distilled water. Dilute 175 minims of solution of sodium hydrate with 3 fluid- ounces of distilled water, and cautiously add enough of this liquid to the iron- albumen mixture to exactly neutralize it. This is shown by the fine, light precipi- tate, first formed, becoming flocculent and settling to leave a clear and nearly colorless supernatant liquid. Wash the precipitate rapidly with distilled water by decantation, until the washings give but a faint cloudiness with silver nitrate test solution. Then drain the precipi- tate on a muslin strainer, transfer it to a porcelain dish, immediately add 141 grains of solution of sodium hydrate, and while stirring add distilled water, not exceeding 4^2 fluidounces, until the precipitate is dissolved. Finally add the alcohol anti aromatic elixir, previously mixed with enough distilled water to make the product measure 31 fluid- ounces. — N. F. Each fluidram of this preparation con- tains about 2/5 of metallic iron in the form of albuminate. II. Ferric chlorid (solid) gr. 72 White of egg, fresh fl.oz. 6 Glycerin fl.oz. 4 Distilled water, to make. .. .fl.oz. 16 Dissolve the ferric chlorid in 2 fluid- ounces of water, mix the egg-white with 4 fluidounces of water, add the iron solution to the egg mixture, allow to stand for 12 hours, then add the glyc- erin, mix, filter, and add enough water through the filter to make a total fil- trate of 16 fluidounces. — Cine. Acad. Pharm. Keep the product in well filled bottles in a cool place. Each fluidounce contains what is about the equivalent of 40 drops of tincture of iron chlorid, U. S. P. III. Egg-white, dry gr. 255 Solution of iron oxy- 23 chlorid av.oz. 2 Solution of soda, U. S. P...m. 75 Cinnamon water, Germ. Pharm fl.dr. 14 Aromatic tincture m. 20 Alcohol fl.oz. 3 Distilled water sufficient Dissolve the egg-white in 16 fluid- ounces of distilled water, strain, and add slowly, with constant stirring, to the iron solution previously diluted with 16 fluidounces of distilled water. To com- pletely precipitate the iron albuminate, neutralize the liquid exactly with Y per cent, solution of soda (3 volumes of U. S. P. solution of soda and 19 of water), adding the liquid slowly and with con- stant stirring. The precipitate is to be washed repeatedly by affusion of water and subsequent decantation of liquid un- til the washings when acidulated with nitric acid do not give more than a slight opalescence with solution of silver nitrate. Then decant to a suitable strainer, allow the liquid to drain, trans- fer the precipitate to a tared bottle, add to it the solution of soda previously mix- ed with 5 fluidrams of distilled water, and agitate until dissolved. Then add the cinnamon water, tincture, and alco- hol, and then enough distilled water to make the product weigh 16^4 av.ounces. — Germ. Pharm. IV. Solution of iron albuminate may also be prepared by dissolving iron al- buminate, which is now commercially available in scale and powder forms, in distilled water, and flavoring in any suitable or desired manner. Solution of Iron and Ammonium Acetate. (Mixture of Iron and Ammonium Acetate, U. S. P. 1880 — Basham's Mixture.) Tincture of iron chlorid fl.dr. 5 Acetic acid, diluted fl.oz. 1 Solution of ammonium ace- tate fl.oz. 8 Aromatic elixir fl.oz. 2 Glycerin fl.oz. 2 Distilled water, to make fl.oz. 16 To the ammonium solution (which should not be alkaline), add, successive- ly, the dilute acid, the tincture, the elixir, and the glycerin, and then enough Sofi STANDARD FORMULARY OF water to make the product measure 16 fluidounces. This preparation should be made freshly, as wanted for use. — U. S. P. The U. S. P., in directing this, to be made as needed, is in error, as when made strictly as directed this is not necessary. This is double the strength of the preparation of the U. S. P. 1890. Solution of Iron and Ammonium Citrate. Iron citrate, soluble av.oz. 8 Distilled water, to make fl.oz. 16 Dissolve and filter. ' Solution of Iron (Ferric), Chlorid. (Solution of Perchlorid or Ses- quichlorid of Iron.) I. Iron, in fine, bright wire, cut into small pieces av.oz. 3 Hydrochloric acid av.oz. 16 Nitric acid. Distilled water, each sufficient Introduce the iron into a flask or bot- tle having the capacity of about 3 pints, pour upon it a mixture of 9^4 av. ounces of hydrochloric acid and S l A fluidounces of distilled water, and heat the mixture upon a water bath for not less than an hour and fifteen minutes, or until effer- vescence ceases ; then heat it to the boil- ing point, filter it through paper, and having rinsed the flask or bottle and wire with a little hot distilled water, pass the rinsings through the filter. To the filtrate add 534 av.ounces of hydro- chloric acid, and then add this mixture, slowly and gradually, in a thin stream, to V/2 av.ounces of nitric acid contained in a capacious porcelain vessel, and warm gently. After effervescence ceases, apply heat, by means of a sand bath, stirring occasionally, until the liquid is free from nitric acid. If the solution has acquired a black color, continue the addition of nitric acid, drop by drop, until red fumes are no longer evolved and the solution assumes a clear red- dish-brown color. Finally add the re- maining 1 av.ounce of hydrochloric acid and enough distilled water to make the product weigh 2^/2 av.ounces or meas- ure 18^4 fluidounces. — U. S. P. While the U. S. P. directs finally to add water to make up a definite weight, in actual practice it may be found neces- sary to evaporate in order to reduce to this weight. A convenient form of iron wire for making this preparation is that which is commercially available under the name "card teeth." The acids for making this preparation must be of full strength, the hydrochloric 31.9 p. c. of absolute acid, the nitric 68 p. c. of absolute caid. The product is an aqueous solution of ferric, chlorid containing not less than 29 p. c. of anhydrous salt, corresponding to about 48 p. c. of crystallized salt (with 12 molecules of water), or to 10 p. c. of metallic iron, and containing also some free hydrochloric acid. II. The Brit. Pharm. recognizes a strong solution of ferric chlorid and a solution of ferric chlorid. The strong solution is made practically like that of the U. S. P., but is slightly stronger, representing almost 16 per cent, of me- tallic iron. The other solution is made by mixing t volume of this solution with 3 vol- umes of distilled water. III. The preparation of the Germ. Pharm. contains only 10 p. c. of metallic iron. Solution of Iron (Ferrous) Chlorid. (Solution of Iron Protochlorid.) Iron, in fine, bright, and fine- ly-cut wire av.oz. 2^4 Hydrochloric acid (U.S. P.) av.oz. n Glycerin fl.oz. 4 Diluted hypophosphorous acid (U. S. P. or 10 p. c.) m. 75 Distilled water, to make. .. .fl.oz. 16 To the iron contained in a flask, add 6 fluidounces of distilled water, and the hydrochloric acid, and apply a gentle heat, until effervescence ceases. Then raise the liquid to boiling, keep it at this temperature for a short time so that the iron may be brought into solution as far as possible, filter the solution through 3 pellet of absorbent cotton placed in the PHARMACEUTICAL PREPARATIONS. 357 neck of a funnel, and wash the cotton with a little distilled water. Evaporate the nitrate, over a boiling water bath, antil crystals begin to form, and the escaping vapors cease to redden, or only slightly affect, moistened blue litmus pa- per. Now add the glycerin and the di- luted hypophosphorous acid, continue the heat, if necessary, until a perfect so- lution is obtained; then transfer the liquid to a graduated bottle, allow it to cool, and add enough distilled water to make 16 fluidounces. Each fluidram represents about 20 gr. of protochlorid of iron (ferrous chlo- rid).— N. F. A convenient and satisfactory form of iron for making this preparation is what is known as "card teeth." Solution of Ferric (Iron) Citrate. Solution of iron (ferric) sul- fate 4. . .av.oz. 16^4 or fl.oz. 12^4 Citric acid av.oz. 6J4 Ammonia water, 10 p. c fl.oz. 17^ Water sufficient Mix the ammonia water with 60 fluid- ounces of cold water, and the iron solu- tion with I2Y 2 pints of cold water. Add the latter solution slowly to the ammo- niacal liquid, stirring constantly. Pour the mixture on a wet muslin strainer, and allow the liquid to run off and the precipitate to drain. Then remove the moist mass from the strainer, mix it well with jYt. pints of cold water, again pour it on the strainer and let it drain. Repeat this washing with several suc- cessive portions of cold water in the same manner, until the washings cease to produce more than a slight cloudiness with barium chlorid test-solution. Then allow the precipitate to drain completely, transfer it to a porcelain capsule, add the citric acid, and heat the mixture on a water bath to 60 deg. C, stirring con- stantly, until the precipitate is dissolved. Lastly, filter the liquid, and evaporate it at the above-mentioned temperature un- til it weighs 20M av.oances or measures 16 fluidounces.-N. F. and U. S. P. 1890. The precipitated ferric hydrate retains enough water to enable the ferric citrate to be dissolved; in fact, as may be ob- served, a portion of the water has to be evaporated from the solution. The product is an aqueous solution of ferric citrate, containing about 35 p. c. of the anhydrous salt, corresponding to about 7^2 p. c. of metallic iron. Solution of Dialysed Iron. ("Dia- lyzed Iron" — Dialyzed Solution of Oxid.) Solution of iron chlorid, U. S. P fl.oz. 5 Ammonia water, 10 p. c, Distilled water, each sufficient Mix 4J4- fluidounces of the iron chlo- rid solution with 20 fluidounces of wa- ter and stir into the mixture sufficient diluted ammonia water to impart a dis- tinct ammoniacal odor. Collect the pre- cipitate on calico or muslin, wash it with distilled water and squeeze the strainer to remove superfluous water. Add the precipitate to the remainder of the solution of iron chlorid, stir thor- oughly, warm gently, and when com- plete, or nearly complete solution is effected, filter if necessary, place the liquid in a dialyzer, and dialyze in the usual manner until the liquid on the dialyzer is almost tasteless. Then add to this liquid enough water to make it measure 16 fluidounces. — Brit. Pharm. Most of the so-called "dialyzed iron" of the market is not prepared by dialysis, but is made by a process the same or very similar to the one given under So- lution of Iron Oxychlorid, which see. The above contains 10 per cent, of iron oxychlorid. The preparation sold in this country usually contains but 5 p. c. of ferric oxid, and it is frequently made to contain one-eighth of its vol- ume of glycerin to prevent gelatinization. Solution of Iron Hypophosphite. This solution is used in making com- pound solutions and syrups of the hypo- phosphites : 358 STANDARD FORMULARY OF Iron and ammonium sulfate (U. S. P.), in perfect crys- tals gr. 600 Sodium hypophosphite gr. 400 Potassium citrate gr. 390 Glycerin fl.dr. 5 Distilled water, to make. . .fl.oz. 4 Dissolve the iron and ammonium sul- fate, and the sodium hypophosphite, each, in 6 fluidounces of the water, and, if necessary, filter each solution. Then mix them, and stir thoroughly; after a few minutes transfer the resulting mag- ma to a close linen or muslin strainer, and wash the precipitate with about 2 fluidounces of water. Allow it to drain, and then press it forcibly in the strain- er, so as to remove as much of the liquid as possible. Transfer the precipi- tate from the strainer to a mortar, add \o it the potassium citrate, and triturate until a perfectly smooth paste results, that may have formed, and keep the so- lution in small, completely-filled and well-corked bottles. II. This preparation may also be pre- pared in the following manner (N. F.) : Iron hypophosphite (ferric).-gr. 300 Potassium citrate gr. 390 Glycerin fl.dr. 5 Distilled water, to make ... fl.oz. 4 Triturate the iron hypophosphite with 3 fluidounces of water to a perfectly smooth mixture, then add the potassium citrate and glycerin, and apply a gentle heat, until solution has been effected. Allow the liquid to cool, and add enough water to make 4 fluidounces. Place the solution for several days in a cold place, if convenient ; then pour off the clear solution from any precipitate or crystals that may have formed, and keep the solution in small, completely-filled and well-corked bottles. Six minims of each of the above solu- tions contain 1 gr. of ferric hypophos- phite, or 1 fluidram contains 10 grs. The following two formulas contain ferrous, instead of ferric, hypophosphite. III. Sodium or potassium hypo- phosphite gr. 360 Ferrous sulfate, pure, clear.. gr. 480 Potassium citrate gr. 400 Glycerin fl.dr 5 Distilled water, to make ... fl.oz. 4 Prepare like No. 1. It is of the same strength as the latter, but contains fer- rous instead of ferric, hypophosphite. IV. The Brit. Form, (last edition) has a formula for a preparation it calls "strong solution of iron hypophosphite :" Ferric chlorid. dry gr. 800 Sodium hypophosphite gr. 880 Citric acid gr. 640 Stronger ammonia water (28 p. c.) fl.dr. 5 y 2 Solution of potash, distilled water, each sufficient Dissolve the chlorid and hypophosphite each in 8 fluidounces of distilled water and pour the solution of the hypophos- phite slowly with stirring into the iron solution. Collect the precipitate and wash it with successive portions of dis- tilled water until the washings are al- most free from chlorid. Dissolve the well-drained precipitate in a solution of the ammonia water and acid in 4 fluid- ounces of distilled water, and filter. De- termine the proportion of iron hypophos- phite present in this solution by the fol- lowing process : Take any small amount of the solution, dilute it with an equal volume of distilled water, add an excess of solution of potash and apply a gentle heat. Collect the precipitate, wash, dry, ignite and weigh the resulting iron ox- ide. The weight in grammes multiplied by the factor 137. 1 will indicate the num- ber of grains of iron hypophosphite in each fluidounce of solution. Adjust the volume of liquid by the addition of dis- tilled water so that each fluidounce shall contain 40 grs. of iron hypophosphite. Ferric hypophosphite is now commer- cially available and may be used instead of making it by precipitation, although when freshly prepared it is more readily soluble. The corresponding preparation of the former Brit. Form, was a solution of ferrous hypophosphite. See No. V. PHARMACEUTICAL PREPARATIONS. 359 V. Ferrous sulfate, crystal, pure gr- 155 Barium hypophosphite (con- taining not less than 95 of Ba. (H 2 P 2 ) 2 , H 2 O gr. 170 Diluted sulfuric acid, U. S. P..m. 30 Distilled water fl-oz. 5 Dissolve the iron salt in 1 fl uidounce of distilled water, and place in a tall bottle of a capacity not less than 5 fluidounces. Dissolve the barium hypophosphite in the remainder of the water, and add slowly with agitation to the iron solution. Add the sulfuric acid, shake again, set aside for 2 days, and decant the clear liquid. Preserve in filled bottles, in a dark place.— Brit. Form. (2nd edit.). Each fluidram contains about 5 grs- of ferrous hypophosphite. Solution of Iron (Ferrous) Iodid. I. Iron, in the form of fine, bright, and finely-cut wire av.oz. 3H Iodin av.oz. 11 Diluted hypophosphorous acid, 10%, fl. dr. 3 Distilled water to make fl. oz. 16 Mix the iron with 12 fluidounces of distilled water in a flask, add about one- half of the iodin, and agitate continuous- ly until the liquid becomes hot. Then moderate the reaction by placing the flask in cold water, or by allowing cold water to flow over it, meanwhile keeping up the agitation. When the reaction has moderated, add one-half of the remain- ing iodin at a time, and carefully mod- erate the reaction each time, in the man- ner above directed. Finally, raise the contents of the flask to boiling and filter immediately through moistened pure fil- tering paper (the point of the filter being supported by a pellet of absorbent cotton) into a bottle containing the di- luted hypophosphorous acid. When all the liquid has passed, rinse the flask with 4 fluidrams of boiling distilled water, and pass this through the filter. Cork the bottle and set it aside to cool. Finally, add enough distilled water to make the product measure 16 fluid- ounces. This solution contains about 8 p. c. of ferrous iodid. On mixing 1 volume with 11 volumes of simple syrup, the product will be practically identical with syrup of iron iodid (U. S. P.). A convenient and satisfactory form of iron for making this preparation is what is known as "card teeth." II. Iron, fine powder av.oz. 3 Iodin av.oz. io^i Distilled water fl.oz. 12 Mix the iodin and water, add the iron gradually, constantly stirring, meanwhile cooling the mixture from time to time if the temperature rises too high; filter the resulting greenish liquid.— Germ. Pharm. The product contains 50 p. c. of fer- rous iodid. Solution of Iron and Manganese Sac- charate. Formula of Berlin Apotheker Verein: Iron oxid, saccharated av.oz. 5 Solution of manganese glu- cosate gr. 380 Alcohol fl.oz. 2 Tincture of orange peel m. 30 Aromatic tincture m. 15 Tincture of vanilla m. 15 Acetic ether drops. 3 Distilled water fl.oz. 11 Dissolve the iron oxid in the water and add the other ingredients. — D. Solution of Iron (Ferric) titrate. (Solution of Pernitrate of Iron.) I. Solution of iron sulfate, av.oz. 2^2, or fl.dr. 14^ Ammonia water, 10 p. c fl.oz. 2^ Nitric acid, gr. 500, or fl.dr. 6 l / 2 Water, distilled water, each, sufficient Mix the ammonia water with 8 fluid- ounces of cold water, and the iron solu- tion with 24 fluidounces of cold water. Add the latter solution slowly to the am- moniacal liquid, stirring constantly. Let the precipitate subside as far as prac- ticable and decant the supernatant liquid. Add to the precipitate 16 fluidounces of cold water, mix well, and again set the mixture aside as before. Repeat the 300 STANDARD FORMULARY OF washing with successive portions of cold water, in the same manner, until the washings cease to produce but a slight cloudiness with barium chlorid test solution. Pour the washed precipitate on a wet muslin strainer, and let it drain thoroughly. Then transfer it to a por- celain capsule, add the acid and stir with a glass rod until a clear solution is ob- tained. Finally, add enough distilled water to make the finished product weigh i6$4 av. ounces or measure IS J A fluidounces. Filter, if necessary. — N. F. and U. S. P. 1890. - The nitric acid should be of full strength, viz. : Containing 68 p. c. of ab- solute acid, in order to produce a solu- tion of normal ferric nitrate. The product is an aqueous solution of ferric nitrate, containing about 6.2 p. c. of the anhydrous salt, and corresponding to about 1.4 p. c. of metallic iron. II. Iron . .. gr. 245 Nitric acid, pure fl.dr. 19^2 Distilled water, to make . . . fl.oz. 16 Dilute the acid with 8> l / 2 fluidounces of the water, add the iron, set aside until the metal is dissolved, taking care to moderate the action, should it become too violent, by the addition of a little more distilled water, filter the liquid, and add enough distilled water to make 16 fluidounces. — Brit. Pharm. This- solution contains 3 p. c. of metal- lic iron, and is therefore more than twice the strength of the U. S. P. solu- tion. Solution of Iron Oxychlorid. Solution of iron chlorid, U. S. P av.oz. 6 Ammonia water, 10 p. c. ..av.oz. 6 Hydrochloric acid, U. S. P...gr. 173 Distilled water, to make. . .av.oz. 18 Mix the ammonia water with 50 fluid- ounces of cold distilled water, and the solution of iron chlorid diluted with 25 fluidounces of cold water. Add the lat- ter slowly to the diluted ammonia water, constantly stirring. Let the mixture stand until the precipitate has subsided as far as practicable, and then decant the supernatant liquid. Add to the precipi- tate 32 fluidounces of cold distilled water, mix well, and again set the mixture aside as before. Repeat the washing with successive portions of cold water in the same manner, until the washings produce only faint opalescence with sil- ver nitrate test solution. Then drain the precipitate on a cloth, express the excess of moisture as much as practicable, transfer it into a jar and mix the hydro- chloric acid with it. Let the mixture stand 3 days, stirring it occasionally, and, if necessary, complete the solution of the ferric hydroxid by heating to about 40 deg. C. Finally, add enough water to make the product weigh 18 av.ounces. — N. F. This is a brown-red, clear, odorless liquid containing about 3.5 p. c. of .iron in the form of oxychlorid. This preparation is official in the Germ. Pharm. and may, according to that authority, be dispensed when solu- tion of dialyzed iron is prescribed. Solution of Iron Oxysulfate. Ferrous sulfate, pure, crys- tal * av.oz. 2^4 Nitric acid (U. S. P.) av.oz. 2.Y\ or fl.dr. 14^ Distilled water, to make. .. .fl.oz. 16 Dissolve the iron salt in i$y 2 fluid- ounces of boiling distilled water, in a flask, gradually add the nitric acid, and continue the heat until the escaping vapors cease to have a nitrous odor. When the reaction is completed, allow the liquid to cool and add enough dis- tilled water to make 16 fluidounces. — ■ N. F. The nitric acid for the above must be of full strength, viz., containing 68 p. c. of absolute acid. Solution of Iron Peptonate. Fresh egg albumen oz. V/2 Pepsin gr. iy 2 Hydrochloric acid m. 30 Sodium citrate gr. 155 Sol. ferric oxychlorid fl.oz. 2 Alcohol fl.oz. 2Vz Syrup fl.oz. 1 %. Glycerin fl.oz. 1 l /^ Oil orange m. 2 PHARMACEUTICAL PREPARATIONS. 361 Acetic ether m. 3 Vanillin gr. 1/5 Sodium hydroxide, Distilled water, each, q. s. Mix the albumen with iy 2 fluid ounces distilled water and strain. Add the hy- drochloric acid and pepsin previously dissolved in y 2 fluid ounce of water, and digest the mixture at a temperature be- tween 40° and 50° C. until no cloudiness is produced by adding two drops of nitric acid to about sixty drops of the solution. Then filter the peptone solu- tion and neutralize the filtrate with so- dium hydroxide prexiously dissolved in about nine parts of distilled water. Now add the solution of iron oxychlorid and the. sodium citrate and warm the mix- ture until the precipitate has dissolved. When cold add the vanillin, acetic ether and oil of orange previously dissolved in the acohol. Finally add the syrup, glycerin and sufficient distilled water to make the product measure 16 fluid ounces. — N. F. Each fluidram contains about 2/5 gr. of metallic iron in the form of peptonate. II. Prepare like solution of iron pep- tonate with manganese, No. II., but omitting the manganese peptonate. — Cine. Acad. Pharm. III. Dietrich-Bartel formula: Solution of iron oxychlorid.fi. oz. 2 Peptone, dry (free from salt) gr. 240 Hydrochloric acid, pure m. 10 Alcohol fl.dr. 12 Brandy fl.dr. 14 Solution of soda, U. S. P., distilled water, each sufficient Mix the iron solution with 32 fluid- ounces of distilled water, and add to this gradually with stirring a solution of the peptone in 32 fluidounces of distilled water. Neutralize the mixture exactly by the cautious addition of solution of soda diluted with 6 times its volume of distilled water, constantly stirring mean- while, about 60 to 70 minims of the solu- tion being required. Wash the precipi- tate repeatedly with distilled water by the process of effusion and decantation until the washings no longer contain chlorid, then collect it on a moistened strainer of thick linen or muslin. After the liquid has drained off, transfer the precipitate to an evaporating dish, add the acid, and heat on a water bath until completely dissolved. To this add the alcohol, brandy and enough distilled water to make 16 fluidounces. Solution of Iron Peptonate with Manganese. This is practically the same as solu- tion iron peptonate, but with the addi- tion of 75 gr. soluble manganese citrate to the pint. — N. F. I. Ferric peptonate gr. 328 Manganese citrate, soluble. . .gr. 58 Ammonia water, 10 p. c m. 100 Aromatic elixir fl.dr. 6y Alcohol fl.oz. 2Y 2 Distilled water, to make. . .fl.oz. 16 Dissolve the peptonate in 4 fluidounces of distilled water, add the ammonia water and then the alcohol. Dissolve the manganese citrate in iY 2 fluidounces of distilled water, add it to the first solu- tion. Then add the elixir and enough distilled water to make 16 fluidounces. If manganese peptonate is available, 188 grs. of this may be used in place of the manganese citrate directed in the above formula. II. Iron peptonate av.oz. 2^ Manganese peptonate gr. 730 Glycerin fl.dr. 6 l / 2 Aromatic spirit fl.dr. 6 l / 2 Spirit of cinnamon fl.dr. 2y 2 Distilled water, to make fl.oz. 16 Dissolve the salts in the glycerin and io l / 2 fluidounces of water, add the two spirits and water to make 16 fluidounces, and filter. — Cine. Acad. Pharm. The solution represents about l /i p. c. of manganese and l /> p. c. of iron. Each fluidram contains about 6 grains of man- ganese peptonate and 9 grains of iron peptonate. The peptonates are now commercially !62 STANDARD FORMULARY OF available, or they may be made by the pharmacist. III. Formula of the Berlin Apotheker Verein: Iron peptonate (with 25 p. c. iron) gr. 184 Solution of manganese glu- cosate gr. 384 Solution of soda, U. S. P m. 220 Tincture of bitter orange peel m. 30 Aromatic tincture m. 15 Tincture of vanilla m. 15 Acetic ether drops 3 Alcohol fl.oz. 2 Simple syrup fl.oz. 2V2 Distilled water fl.oz. 9M Dissolve the iron peptonate in S J A fluidounces of hot distilled water; allow to cool, add the syrup, then add gradual- ly with frequent agitation the solution of soda previously mixed with 1^4 fluid- ounces of distilled water. The alkali is in slight excess so as to redissolve the precipitate. To the liquid add the man- ganese solution which has previously been mixed with a small quantity of solution of soda to render it slightly alkaline. To the clear liquid add the re- maining ingredients previously mixed to- gether. — D. The solution is slightly alkaline and represents 0.6 p. c. of metallic iron and 0.1 p. c. of metallic manganese. Solution of Iron Phosphate. I. Iron phosphate, soluble av.oz. 8 Distilled water, to make fl.oz. 16 II. Puchner's formula for a solution of which 2 Cc are equivalent to 1 gram of soluble ferric phosphate : Ferrous sulfate, pure, clear crystals av.oz., 2, gr. 265 Sulfuric acid m. 160 Potassium chlorate gr. 132 Ammonia water, 10 p. c. .fl.oz. 5J/2 Citric acid av.oz. 2 Sodium phosphate, unefnor- esced av.oz., 3, gr. 145 Water sufficient Add the sulfuric acid to 4 fluidounces of water contained in a glass or por- celain vessel, to this add the ferrous sul- fate, warm gently until all is dissolved, then add the potassium chlorate and con- tinue the heat for one-half hour, or until a drop of the solution added to potas- sium ferricyanid test solution no longer produces a distinct green or bluish-green color. Add this solution slowly and with constant agitation to the ammonia water contained in a suitable vessel; to this mixture add 64 fluidounces of hot water, allow to subside, and after one-half hour decant or siphon off the clear superna- tant liquid. To the residue add 32 fluid- ounces of hot water, allow to subside, and decant ; repeat this washing with six portions of hot water, allowing the last portion to subside for at least six hours or over night. Decant or siphon off the clear liquid as closely as possible, then add to the remaining magma the citric acid and the sodium phosphate, warm gently until solution results, and then evaporate on a water bath at a temper- ature not exceeding 60 deg. C, until the solution measures 8 fluidounces. Solution of Iron "Protoxide." (So- lution of Iron Protocitrate— -So- lution of Ferrous Citrate.) Ferrous sulfate, pure, crys- tal av.oz. 2> l A Sodium carbonate, pure, crystal av.oz. 3^ Citric acid av.oz. 2 Distilled water, simple syrup, each sufficient Dissolve the two salts separately in 32 fluidounces of water, mix by adding the iron solution to the sodium solution with constant stirring, collecting the precipi- tate, washing it quickly with more water, until the washings are tasteless, then dis- solve by the aid of a gentle heat in 4 fluidounces of water containing the citric acid and add enough simple syrup to make 16 fluidounces. Solution of Iron Pyrophosphate. Iron pyrophosphate, soluble.av.oz. 8 Distilled water, to make fl.oz. 16 Solution of Iron and Quinine Citrate. Citrate of iron and quinine, soluble av.oz. 8 Distilled water, to make. .. .fl.oz. 16 Dissolve and filter. PHARMACEUTICAL PREPARATIONS. 363 Solution of Iron Salicylate. Sodium salicylate oz. 2 Tr. iron citro-chloride fl.oz. 2 Ammonium carb gr. 50 Citric acid gr. 66 Glycerin fl.oz. 3 Distilled water, to make fl.oz. 16 Dissolve the citric acid in Zy 2 fluid ounces distilled water, add the ammon- ium carbonate and dissolve the sodium salicylate in this solution. Then add the tincture of iron citro-chloride, glyc- erin and the oil of wintergreen, and, after mixing, sufficient distilled water to make the product measure 16 fluid ounces, and filter. — N. F. Solution of Iron (Ferric) Subsulfate. (Solution of Basic Ferric Sulfate — Solution of Persulfate of Iron — Monsel's Solution.) Ferrous sulphate, pure, clear crystals av.oz. i&A Sulfuric acid av.oz. ift Nitric acid, distilled water, each sufficient Add the sulfuric acid to 13 fluid- ounces of distilled water in a capacious procelain vessel, heat. to nearly 100 deg. C, then add 1% av.ounces or 10 fluid- drams of nitric acid, and mix well. Di- vide the ferrous sulfate, coarsely pow- dered, into four equal portions, and add these portions, one at a time, to the hot liquid, stirring after each addi- tion until effervescence ceases. When all the ferrous sulfate is dissolved, add a few drops of" nitric acid, and if this causes a further evolution of red fumes, continue to add nitric acid, a few drops at a time, until it no longer causes red fumes to be evolved, then boil the solu- tion until it assumes a ruby-red color and is free from nitric acid. Lastly add enough distilled water to make the prod- uct weigh 27 av.ounces or measure 16^4 fluidounces. — U. S. P. The two acids must be of full strength, the sulfuric containing 92^ p. c. of ab- solute acid, the nitric 68 p. c. of absolute acid. The product should be kept in well- stoppered bottles, in a modertly warm place (not under 22 deg. C), protected from light. This solution will sometimes crystal- lize, forming a semi-solid, whitish mass. When this occurs, the application of a gentle heat to the bottle will restore the liquid condition. The product is an aqueous solution of basic ferric sulfate — this is not a definite compound — containing about 44 p. c. of this compound, corresponding to about 13.6 p. c. of metallic iron. This preparation should be dispensed when solution of persulfate of iron is wanted. Solution of Iron (Ferric) Sulfate. (Solution of Normal Ferric Sul- fate — Solution of Tersulfate of Iron.) Ferrous sulfate, pure, clear crystals av.oz. 10J/2 Sulfuric acid av.oz. 2 Nitric acid, distilled water, each sufficient Add the sulfuric acid to about 5 fluid- ounces of distilled water in a capacious porcelain vessel, heat the mixture to nearly 100 deg. C, then add 510 grains or 6 z /2 fluidrams of nitric acid, and mix well. Divide the ferrous sulfate, coarse- ly powdered, into four equal parts, and add these portions, one at a time, to the hot liquid, stirring after each addition until effervescence ceases. When all tlie ferrous sulfate is dissolved, if the solu- tion has acquired a black color, add nitric acid, a few drops at a time, heat- ing and stirring until it no longer causes red fumes to be evolved, and the solu- tion assumes a clear reddish-brown col- or; then boil the liquid until it is free from nitric acid. Lastly add enough distilled water to make the product weigh 21 av.ounces (measure about 14^4 fluidounces). Filter if necessary. — U. S. P. The two acids should be of full strength, viz., 68 per cent, of absolute nitric acid and 92^2 per cent, of absolute sulfuric acid. The product is an a^ieous solution of 364 STANDARD FORMULARY OF normal % ferric sulfate, containing about 36 per cent, of this salt, corresponding to not less than 10 per cent, of metallic iron. The preparation of the Brit. Pharm. is practically the same as that of the U. S. P. Solution of Lead Subacetate. (Gou- lard's Extract — Strong Solution of Lead Subacetate — Acetum Plumbi or Saturni — Blei Essig or Extrakt.) I. Lead acetate, pure, crystal. av.oz. 4H2 Lead oxid, pure av.oz. 2^4 Distilled water, to make av.oz. 25 Dissolve the acetate in 18 fluidounces of boiling distilled water, add this solu- tion slowly and in portions with con- stant stirring to the lead oxid (in finely powdered condition) contained in a por- celain dish of the capacity of about 1 quart, and boil the liquid for H hour, with occasional stirring. Finally, when cool, filter the solution and add enough distilled water, which has previously been boiled and cooled, to make the product weigh 25 av.ounces (measure about 20 fluidounces). It is best filtered in a closely-covered funnel to exclude air. This solution should be preserved in well-stoppered bottles. — U. S. P. This is an aqueous liquid, containing in solution not less than 25 per cent, of lead subacetate. This preparation may also be made without heat, the ingredients being mixed in a bottle and allowed to stand for several days, agitating frequently, until the oxid becomes white, then filter- ing as before. II. The Brit. Pharm. directs 4 av.- ounces and 75 grains of lead acetate and 2 av.ounces and 400 grains of lead oxid to make 16 fluidounces of solution, and is about one-fourth stronger than the U. S. P. solution. III. Lead acetate av.oz. 4^2 Lead oxid av.oz. i l / 2 Distilled water fl.oz. 1454 Triturate the two lead compounds and heat in a covered vessel on a water bath with 6 fluidrams of the water until the yellowish color of the mixture has changed to white or reddish-white. Then gradually add the remainder of the wa- ter, set aside in a closed vessel, allow to settle, and filter.— Germ. Pharm. Solution of Lead Subacetate^ Dilut- ed. (Lead Water — Goulard's Lo- tion or Water — Blei Wasser — Aqua Plumbi or Saturnini.) Solution of lead subacetate. fl.oz. 1 Distilled water, previously boiled and cooled fl.oz. 2(^/2 Keep in well-stoppered bottles. The product contains 1 p. c. by weight of lead subacetate. — U. S. P. The preparation of the Brit. Pharm. is made from 192 minims of strong solu- tion (equivalent to V 2 fluidounce of the U. S. P. solution of lead subacetate), the same amount of alcohol, and enough recently boiled and cooled distilled wa- ter to make 32 fluidounces. The alcohol is to be mixed with the water, and then the solution is to be agitated with this mixture. The preparation of the Germ. Pharm. is to be made from 1 part by weight of the strong solution (of the Germ. Pharm.) to 49 of water, equivalent to about J / 2 fluidounce of the former to enough of the latter to make 32 fluid- ounces. Solution of Licorice Extract. Purified extract of licorice.. sufficient Alcohol fl.oz. 2 Glycerin fl.oz. 4 Water, to make fl.oz. 16 In a small portion of purified extract of licorice, weighed into a tared capsule, determine the amount of water, by dry- ing it to a constant weight. Then take of this extract a quantity equivalent to 4^4 av.ounces of dry extract, dissolve this, on a water bath, in 4 fluidounces of water, add the glycerin, and allow the liquid to cool. Lastly, add the alcohol, and enough water to make 16 fluid- ounces. PHARMACEUTICAL PREPARATIONS. 365 Each fluidram represents 15 grains of dry extract of licorice. See also Glycerite of Licorice, which is double the strength of the above. Solution (Test) of Litmus. I. Exhaust powdered litmus with three separate and successive portions (rep- resenting about 4 times its weight) of boiling alcohol (which removes the un- desirable color erythrolitmin), each ex- traction lasting for about an hour. After draining off the alcohol, digest the resi- due with about an equal weight of cold water, and filter. (This blue solution, which contains some alkali, after being acidulated, may be used to make red lit- mus paper.) Finally extract the residue with about 5 times its weight of boiling water, and, after thoroughly cooling, fil- ter. The addition of 1 drop of tenth-nor- mal acid or alkali volumetric solution to 50 cc. of water containing 5 drops of lit- mus, solution should produce a distinct change in color. — U. S. P. Preserve the solution in wide-mouthed bottles stoppered with loose plugs of cot- ton so as to exclude dust but to admit air. II. Litmus, powder grams 20 Alcohol cc. 200 Distilled water cc. 200 Boil the litmus with 80 cc. of the al- cohol for one hour, pour away the clear liquid, repeat this operation with 60 cc. of alcohol, and then for a third time with the remainder of the alcohol. Di- gest the washed litmus in the distilled water, and filter the liquid. — Brit. Pharm. Solution of Magnesium Carbonate. (Fluid Magnesia.) Magnesium sulfate av.oz. 2 Sodium carbonate, crystal, pure av.oz. 2^2 Distilled water sufficient Dissolve the salts separately each in J)H fluidounces of distilled water, heat the magnesium solution to boiling, add to it the sodium solution, boil them to- gether until carbonic acid gas is no longer evolved, collect the precipitated magnesium carbonate on a muslin strain- er, and wash it with distilled water un- til free from sulfate. Mix the washed precipitate with 19 fluidounces of dis- tilled water, place the mixture in a suit- able apparatus, force into it pure car- bonic acid gas, let the mixture remain in contact with excess of the gas, re- tained under a pressure of three atmos- pheres, for 24 hours or longer, and de- cant the solution, into which again pass carbonic acid gas. The solution should be kept in bottles of convenient size, securely closed to prevent escape of the gas. — Brit. Pharm. When the bottles are opened, the solu- tion effervesces only slightly or not at all. Each fluidounce of solution contains nearly 10 grains of magnesium carbon- ate in the form of bicarbonate or acid carbonate of magnesium produced by contact of carbonic acid gas with mag- nesium carbonate. Solution of Magnesium Borocitrate. This may be prepared as follows : Magnesium carbonate, powd..gr. 310 Citric acid gr. 620 Borax, powder gr. 620 Water, to make fl.oz. 16 Dissolve the citric acid in 2 fluidounces of water at a boiling temperature, add the magnesium carbonate and afterward the borax, filter, and then add the re- mainder of the water. The solution contains about 10 gr. of the dry magnesium borocitrate in each fluidram. Solution of Magnesium Bromid. Diluted hydrobromic acid (U. S. P.) fl.oz. 8 Magnesium carbonate sufficient Saturate the acid with a sufficient quantity (240 grains) of magnesium car- bonate. When effervescence has ceased, filter. Each fluidram contains about lY* gT- of magnesium bromid. 366 STANDARD FORMULARY OF Solution of Magnesium Chlorid. Homeopathic : ix solution is to be made from 46 grains of anhydrous salt and 1 fluid- ounce of distilled water. 2x and higher solutions are to be made from this by adding distilled water according to the directions given under Dilutions, Home- opathic. Solution of Magnesium Citrate. I. Magnesium carbonate gr. 230 Citric acid •••••• gr. 508 Syrup of citric acid fl.oz. 2 Potassium bicarbonate gr. 38 Distilled water, to make. . .fl.oz. 12 Dissolve the acid in 4 fluidounces of water, add the magnesium carbonate, stir until it is dissolved, filter into a suitable 12-ounce bottle containing the syrup, then add water to nearly fill the bottle, drop in the potassium bicarbon- ate, and immediately stopper the bottle securely. Lastly, shake the mixture oc- casionally until the bicarbonate is dis- solved.— U. S. P. This solution should be freshly pre- pared when wanted. While the U. S. P. does not state that distilled water should be used, this should be preferred as it makes a more transparent and permanent preparation. Innumerable formulas have been of- fered for this preparation. In some the amounts of acid and magnesium carbo- nate differ from that of the above, in others again calcined magnesia is used. See No. II. Other solutions are used as substi- tutes for the above, among them being effervescent solutions of magnesium sul- fate and of sodium citrate. See Solution of Magnesium Sulfate, Effervescent, and Solution of Sodium Citro-Tartrate, Ef- fervescent. II. Citric acid . ... gr. 360 Magnesia, calcined gr. 105 Syrup of citric acid fl.oz. 1 Potassium bicarbonate, crys- tal gr. 40 Distilled water, to make. . . .fl.oz. 12 Mix the acid, magnesia and 4 fluid- ounces of water, stir or agitate until dis- solved, add the syrup and the remainder of the water, filter, introduce the clear filtrate into a suitable bottle, add the potassium salt, and cork and tie over the bottle immediately. — Parrish. The above is intended for 1 bottle. Solution of Magnesium Sulfate, Ef- fervescent. (Liquor Magnesiae Effervescens.) Magnesium sulfate gr. 360 Citric acid .. gr. bo Syrup of citric acid fl.oz. 2 Potassium bicarbonate, crys- tals ...gr. 35 Water, to make fl.oz. 12 Dissolve the magnesium sulfate and the acid in 8 fluidounces of water, add the syrup of citric acid, and filter the solution into a strong bottle of about 12 fluidounces capacity. Then add enough water to nearly fill the bottle, drop in the crystals of potassium bicarbonate, immediately close the bottle with a cork, and secure it with twine. Lastly, shake the bottle occasionally, until the crystals are dissolved. — N. F. This preparation is to be bottled in what are commonly known as "citrate of magnesia bottles." It is a substitute for solution of magnesium citrate. Solution of Manganese Glucosate. Formula of Berlin Apotheker Verein : Potassium permanganate ....gr. 224 Grape sugar, crystallized. . . . av.oz. 3 . . gr. 268 Soda (pure caustic soda) gr. 82 Alcohol, distilled water, each sufficient Dissolve the potassium salt in 27 fluid- ounces of hot distilled water, allow the solution to cool to about 60 deg. C, and add to it 121 grains of the sugar. After an hour, wash the precipitate twice with distilled water by the process of affusion and decantation, transfer it to a suitable strainer, allow the liquid to drain, press the precipitate lightly to remove most of the water, and transfer it to a por- celain capsule. Dissolve the soda in g l / 2 fluidrams of distilled water, add this and the remainder of the sugar to the magma in the capsule, and heat on a water bath PHARMACEUTICAL PREPARATIONS. 367 until the mixture is completely soluble in water. Dilute the liquid with enough distilled water to which has been added 5 per cent, of alcohol to make the total weigh 8 av.ounces. — D. The product contains the equivalent of 2 per cent, of metallic manganese. Dry manganese glucosate may be pre- pared by evaporating 3 fluidounces of the above solution to dryness on a water bath, and rubbing with enough sugar to make 2 av.ounces. Solution of Mercury Albuminate. Egg albumen, fresh gr. 585 Mercuric chlorid, pure gr. 39 Sodium chlorid gr. 156 Distilled water fl.oz. 8 Beat the egg albumen to foam, allow this to become liquid again by standing, and then add to it a solution of the two salts in the water. Set the liquid aside for two days in a cool and dark place, and filter. This preparation must be kept in the dark. It contains 1 per cent, of mercu- ric chlorid. — Germ. Form. A preparation containing 5 .p. c. of mercuric chlorid may be made by using 975 gr- of fresh egg-white, 195 grains of mercuric and sodium chlorids, and 6 l / 2 fluidounces of distilled water. Solution of Mercuric and Ammonium Chlorid. (Van Swieten's Solution or Liquor.) Mercuric chlorid gr. 7^2 Ammonium chlorid gr. 15 Alcohol fl.dr. 2 Orange flower water fl.oz. 8 Distilled water, to make. ,. .fl.oz. 16 Dissolve the salts in iY 2 fluidounces of water, and add the other ingredients. This solution should be kept in dark or amber-colored bottles. — Cine. Acad. Pharm. See also Solution of Mercury Chlorid, No. II. Solution of Mercury Chlorid. (Solu- tion of Mercury Perchlorid or Bichlorid.) I. Brit. Pharm.: Mercuric chlorid gr. 2 Distilled water fl.oz. 4 Dissolve. II. Mercuric chlorid gr. 2 Ammonium chlorid gr. 2 Distilled water fl.oz. 4 —Eclectic (from Brit. Pharm. 1885). These solutions contain 1/16 gr. of mercuric chlorid in each fluidram. Solution of Mercuric Nitrate. (Acid Solution of Nitrate of Mercury.) Red mercuric oxid av.oz. 4 Nitric acid av.oz. 4^2 Distilled water av.oz. i>4 Mix the acid with the water, and dis- solve the oxid in the mixture. — N. F. Keep the product in glass-stoppered bottles. The product contains about 60 p. c. of mercuric nitrate, with about 11 p. c. of free nitric acid. Acid Solution of Mercuric Nitrate of the Brit. Pharm. contains about same amount of mercuric nitrate as the above but is considerably more acid, being pre- pared from 4 av.ounces of mercury, 5 fluidounces of nitric acid and liy 2 fluid- drams of distilled water. Mix the acid with the water in a flask, dissolve the mercury in the mixture without the ap- plication of heat, boil gently for 15 min- utes, allow to cool, and preserve the solution, which should weigh about three times as much as the mercury employed, in a stoppered bottle not exposed to light (an amber bottle will suffice). Solution of Mercury Peptonate. Mercuric chlorid, pure gr. 18 Peptone, dry (free from salt) .gr. 54 Sodium chlorid gr. 14 Distilled water sufficient Dissolve the mercury salt in 6 fluid- drams of the water and mix this with a solution of the peptone in 3 fluidrams of the water. After one hour, collect the precipitate on a filter, allow it to drain, add it to a solution of the sodium chlo- rid in 2 fluidounces of the water, and when dissolved add enough water to make 4 fluidounces. — Germ. Form. This contains 1 p. c. by weight of mercuric chlorid. 368 STANDARD FORMULARY OF Solution of Mercury and Potassium Iodid. (Solution of Potassium Iodohydrargyrate — Channing's Solution.) Red mercuric iodid gr. 9 Potassium iodid gr. 7 Distilled water fl.oz. 2 Dissolve the salts in the water.— N. F. Solution of Morphine Acetate. I. Morphine acetate gr. g Acetic acid, diluted m. 20 Alcohol fl.dr. 4 Distilled water fl.dr. 12 —Brit. Pharm. II. Eclectic (from Brit. Pharm. 1885) : Morphine acetate gr. 4 Distilled water n.oz. 4 Diluted acetic acid m. 5 Solution of Morphine Citrate. Morphine (alkaloid) gr. 32 Citric acid gr. 27 Cochineal gr. 1 Alcohol fl.dr. 2 Distilled water, to make fl.oz. 2 Triturate the solids with the alcohol and 1% fluidounces of water, filter, and pass the remainder of the distilled water through the filter. This solution should not be kept on hand, but prepared only when required. Each fluidram contains 2 gr. of mor- phine in the form of citrate. Solution of Morphine Hydrochlorid. (Solution o* Morphine Muriate.) I. Morphine hydrochlorid gr. 9 Hydrochloric acid, diluted. .. .m. 20 Alcohol fl.dr. 4 Distilled water fl.dr. 12 —Brit. Pharm. II. Eclectic : Morphine hydrochlorid gr. 4 Distilled water fl.oz. 4 Diluted hydrochloric acid m. 5 Solution of Morphine, Magendie's. (Hypodermic Solution of Mor- phine.) Morphine sulfate gr. 32 Salicylic acid gr. 1 Distilled water, warm fl.oz. 2 Dissolve the morphine and acid in the warm distilled water and filter the solu- tion through a small pellet of absorbent cotton. When the solution is cold, pass a small amount of distilled water through the cotton, if necessary, to make the liquid measure 2 fluidounces. Keep the solution in well-stoppered vials, in a dark place. Particular care should be taken in dis- pensing and labeling this solution so that it may not be mistaken for the Solution of Morphine, U. S. P. 1870, containing only 1 gr. of morphine sulfate in each fluidounce, which is still used in some parts of this country. The addition of salicylic acid as a pre- servative is an innovation, intended to give stability to the solution if it is to be kept in stock. It may be omitted if the solution is prepared for immediate use. Other preservatives recommended for hypodermic solutions are chloroform wa- ter instead of distilled water, a small amount of benzoic acid, or about 5 grains of boric acid to a fluidounce of solution. Solution of Morphine Meconate. (So- lution of Morphine Bimeconate.) Morphine meconate gr. 22 Alcohol^ fl.dr. S l / 2 Comp. tincture of cudbear m. 15 Distilled water, to make fl.oz. 4 Dissolve the morphine salt in 4 fluid- ounces of water, add the alcohol, the tincture, and enough water to make 4 fluidounces. Each fluidounce contains s l A grains of morphine meconate, or 22 minims (about 66 drops from a dropper) con- tains % gr. of the salt. This solution is about as strong as tincture of opium U. S. P. by measure and two-thirds as strong by the drop- per. — Cine. Acad. Pharm. This is similar to the Solution of Morphine Bimeconate of the Brit. Pharm. 1885 (not in 1898), which, in simplified or modified form, is as fol- lows: Morphine (alkaloid) gr. 13^ Meconic acid gr. 12 Alcohol fl.oz. 1 Distilled water, to make fl.oz. 4 PHARMACEUTICAL PREPARATIONS. 369 Add the morphine and acid to the al- cohol, then add the water, dissolve by agitation, and filter through white pa- per. Solution of Morphine Sulfate. Morphine sulfate gr. I Distilled water fl.oz. I — U. S. P. 1870 and Eclectic. This solution should not be confound- ed with the solution of morphine of the X. F. or what is commonly known as Magendie's Solution. Solution of Morphine Tartrate. Morphine tartrate gr. 18 Alcohol rl.oz. 1 ■ Distilled water, to make rl.oz. 4 Dissolve the morphine salt in the al- cohol mixed with an equal volume of the water, then add the remainder of the water. — Brit. Pharm. Solution of Opium, Compound or Squibb's. (Liquor Opii Composi- tus.) Squibb's formula is Depurated solut'n of opium, fl.dr. 14 (equal to 20 gr. of morphine sulfate) Alcohol fl.dr. 13 Chloroform fl.dr. 1 Acetic ether fl.dr. 2 The depurated solution of opium is a preparation made practically like de- odorized tincture of opium. The above is the formula given in 1870. The solution of opium for the above is now stated to contain 25^2 gr. of morphine. This is not to be confounded with Squibb's diarrhea mixture; see Mix- tures, Cholera. Solution of Opium, Sedative. (Batt- ley's Sedative Liquid or Drops.) The formula usually employed is simi- lar to, or the same as, the following from Cooley: Extract of opium gr. 132 Alcohol fl.dr. 5 Water, to make rl.oz. 4 Dissolve the extract in hot water, al- low to cool, add the alcohol and the re- mainder of the water, and filter. Solution, Pancreatic. (Liquor Pan- creaticus.) I. Pancreatin (U. S. P.) gr. 128 Sodium bicarbonate gr. 360 Glycerin fl.oz. 4 Comp. spirit of cardamom.. fl.dr. 4 Alcohol fl.dr. 4 Purified talcum gr. 120 Water, to make. ". fl.oz. 16 Triturate the pancreatin and the so- dium bicarbonate gradually with 10 fluidounces of water; add the alcohol, compound spirit of- cardamom and tal- cum; mix them thoroughly by shaking, and pour the mixture upon a wetted filter, returning the first portions of the filtrate, until it runs off clear. Wash the filter with enough water to obtain 12 fluidounces of filtrate. To this add the glycerin. Each fluidram represents 1 grain of pancreatin (U. S. P.).— N. F. Tests for pancreatin are mentioned under Powder, Peptonizing, which see. II. Pancreas, fresh av.oz. 4^2 Glycerin fl.oz. 1 Alcohol fl.oz. 1 Water fl.oz. 12 Mix the pancreas, previously commi- nuted, with the liquids, macerate for several weeks, frequently shaking, and finally strain. The liquid portion may be used as soon as the red blood color has disap- peared. III. Macerate 5 av.ounces of pancreas, freed from fat and external membrane and finely divided by trituration with washed sand or powdered pumice, in a closed vessel with 19J4 fluidounces of 20 p. c. alcohol (4 fluidounces of U. S. P. alcohol and isVa of water) for 7 days, and filter. — Brit. Pharm. Solution of Pepsin. (Liquid Pepsin.) Glycerite of pepsin fl.dr. 6 Hydrochloric acid m. 75 Glycerin fl.oz. 5 Water, to make fl.oz. 16 Mix the glycerite, acid, and glycerin, add the water, mix well, and filter after 3 TO STANDARD FORMULARY OF standing a convenient time, if necessary. — N. F. and U. S. P. 1880. Solution of Pepsin, Aromatic. (Aro- matic Liquid Pepsin.) Pepsin (U. S. P. or 1:3000). gr. 128 Oil of cinnamon drops 2 Oil of pimento drops 2 Oil of clove drops 4 Purified talcum gr. 120 Alcohol fl.dr. 4 Hydrochloric acid m. 75 Glycerin fl.oz. 4 Water, to make fl.oz. 16 Mix the pepsin with 8 fluidounces of water and the acid, and shake the mix- ture frequently until the pepsin is dis- solved. Then i:dd the talcum and oils, previously dissolved in the alcohol ; mix the whole thoroughly, by agitation, and filter it through a wetter filter, returning the first portions of the liquid until it runs through clear. Pass enough water through the filter to make the filtrate measure 12 fluidounces. To this add the glycerin. Each fluidram represents 1 gr. of Pep- sin (U. S. P.).— N. F. Solution of Pepsin, Antiseptic. The antiseptic solution is three times the strength of the above, in pepsin, and contains 4 grains each of menthol, euca- lyptol and oil of wintergreen, to the pint. Ihe solution is glycerin, diluted hydro- chloric acid in the proportion of 5 to 2, in sufficient water. — N. F. Solution of Peptonate of Iron, See Solution of Iron Peptonate. Solution of Peptonate of Iron and Manganese. See Solution of Iron Peptonate with Manganese. Solution (Test) of Phenolphthalein. Dissolve 1 gm. of phenolphthalein in 50 cc. of alcohol and dilute to 100 cc. with water. About 3 drops are sufficient for 50 cc. of the solution to be titrated; it gives a red color to alkali hydroxids or carbonates, while acids render the solution colorless. It may be employed in hot titrations. It is not suitable as an indicator for ammonia, but is largely used for organic acids, alkali hydroxids and for carbonates and bicarbonates in boiling solutions. — U. S. P. Solution of Phosphorus. (Thompson's Solution of Phosphorus.) Phosphorus gr . 1 Absolute alcohol fl.dr! &3/ Spirit of peppermint (U.S.P.).m. 10" Glycerin fl. oz# 2 Dissolve the phosphorus in 1 fluid- ounce of absolute alcohol, in a stoppered vial or test-tube, by -immersion in a water bath and frequent agitation, ta- king care that any loss of alcohol, by evaporation, be made up from time to time. Allow the solution to become nearly cold, and then add to it the re- mainder of the absolute alcohol and the glycerin, previously mixed and slightly warmed. Finally add the spirit of pep- permint. Keep the solution in a well-stoppered bottle, in the dark. Each fluidram contains about 1/24 gr. of phosphorus. This solution must not be confound- ed with spirit of phosphorus, which is not intended to be administered as such, but is only to be used in compounding the elixir or other preparations of phos- phorus. The phosphorus should be perfectly translucent, cut and weighed under wa- ter, and quickly dried with filtering pa- per before being dropped into the al- cohol.— N. F. Solution of Potassa. (Solution of Potassium Hydroxid, IT. S. P. 1900— Solution of Caustic Potash Kali Lauge.) Potassa (i. e., purified caustic potassa) av-0z< j Distilled water, to make. .. .fl.oz. 16 The potassa should be of the full strength (85 per cent.) and quality di- rected by the U. S. P. Potassa of any other strength, however, may be used if a proportionately larger or smaller quantity be taken. This solution should be kept in bot- tles made of green glass and provided with glass stoppers coated with paraffin or petrolatum.— U. S. P. PHARMACEUTICAL PREPARATIONS. 371 The product is an aqueous solution of potassium hydroxid containing about 5 per cent, of this compound. In the U. S. P. 1890, this preparation was directed to be made by interaction between lime (calcium oxid) and po- tassium bicarbonate as follows : Potassium bicarbonate gr. 640 Lime gr. 300 Distilled water sufficient Dissolve the potassium salt in 7 fluid- ounces of distilled water, heat the solu- tion until effervescence ceases, and then increase the heat to the boiling point of the liquid. Slake the lime with about 3 nuidrams of distilled water, mix this with 7 fluidounces of distilled water, pour the mixture into a tared flask, and, having heated it to boiling, gradually add to it the solution of potassium bi- carbonate, and boil during 10 minutes. Then add enough distilled water to make the liquid weigh 16 H av.ounces (measuring about 16 fluidounces), set the flask aside, well stoppered, until the contents are cold. Lastly, strain the liquid through linen, set it aside in a well-stoppered bottle until it has be- come clear by subsidence, and separate the clear solution by decantation or by means of a siphon. This preparation may also be made in the cold, first heating the bicarbonate as in the above, slaking the lime, adding distilled water to each, mixing them in a bottle, adding enough of the water to make the proper weight, allowing to stand for several days, agitating fre- quently, then clarifying like the above. The preparation of the Brit. Pharm. conatins approximately 5 per cent, of po- tassium hydrate, that of the Germ. Pharm. 15 per cent. Solution of Potassium Acetate. (Li- quor Kali Acetici.) I. Acetic acid, 36 p. c fl.oz. 10^4 Potassium bicarbonate, Distilled water, each sufficient To the acid add 2% fluidounces of water, add gradually 6^ av.ounces of potassium bicarbonate, heat the liquid to 24 boiling, then neutralize by the further addition of the potassium salt, and then add enough water to produce a liquid of a sp. gr. between 1.176 and 1.180. — Germ. Pharm. II. (Also called Solution of Kali Ace- tate) : Potassium acetate gr. 183 Distilled water fl.oz. 4 — Homeopathic. This is a ix solution. Dilutions are to be made from this with distilled wa- ter. See Dilutions, Homeopathic. All preparations of this salt should be freshly made as required. Solution of Potassium Arsenate and Bromid. (Solution of Arsenic Bromide — Clemens' Solution — Liquor Arsenic Bromidi.) Arsenic trioxid gr. 73 Potassium bicarbonate gr. 294 Bromin gr. 118 Distilled water, to make. . .fl.oz. 16 Boil the acid with the potassium bi- carbonate, and 4 fluidounces of water, until solution is effected. Allow this to cool, add 8 fluidounces of water, then the bromin, and afterwards enough wa- ter to make 16 fluidounces. Let the mixture stand a few hours, agitating it occasionally, then filter. This solution contains an amount of arsenic in combination, corresponding to 1 per cent, of arsenous acid. The title "solution of arsenic bromid," which is often applied to Clemens' solu- tion or similar preparations, is a mis- nomer, since arsenic bromid cannot ex- ist, as such, in presence of water, but is split up into hydrobromic and arsen- ous acids. The proportions of the in- gredients, in the formula above given, have been adjusted, as closely as prac- ticable, so as to yield definite com- pounds, viz., arsenate and bromid of potassium. In order to prevent injury to the bal- ances by weighing a definite amount of bromin, the plan suggested under Solu- tion of Bromin may be applied to this preparation, viz., to prepare such a quan- tity of the latter at one time, as will be 372 STANDARD FORMULARY OF commensurate to the actual contents of an original vial of bromin. — N. F. Solution of Potassium Arsenite. (Fowler's Solution — Liquor Ar- senicalis — Arsenical Solution — Liquor Kali Arsenicosi— -Solutio Arsenicalis Fowleri.) I. Arsenous acid g". 70 Potassium bicarbonate gr. 140 Comp. tincture of lavender, .gr. 210 Distilled water, to make, .av.oz. 16 The arsenous acid (arsenic tricxid or arsenous oxid) should be rubbed to fine powder, then boiled with the potassium bicarbonate, in a tared dish, with about i l / 2 fluidounces of water until dissolved, then add enough water so that with the tincture the whole will weigh 16 av.- ounces, and filter through paper. — U. S. P. The product contains 1 per cent, by- weight of arsenous acid. In the U. S. P. 1890 this preparation was made up to a certain quantity by volume, viz., 73 gr. of arsenous acid, 146 gr. of potassium bicarbonate, 4 fluid- drams of compound tincture of laven- der, and enough distilled water to make 16 fluidounces. The arsenous acid used should be the pure, not the ordinary commercial vari- ety in powder form. The preparation of the Brit. Pharm. is of the same strength of arsenic but is made with 73 grains of potassium car- bonate instead of the bicarbonate. The preparation of the Germ. Pharm. differs from that of the Brit. Pharm. in that 16 fluidounces contain 7 fluidrams of spirit of lavender and 14 of alcohol. II. Solution of Kali Arsenite: This is prepared like the U. S. P. solution but omitting the compound tinc- ture of lavender, and adding 6 l / 2 fluid- drams of alcohol to the solution before adding the full amount of water. — Ho- meopathic. This makes a 2x solution, from which dilutions are to be made with dispensing alcohol. See Dilutions, Homeopathic. Solution of Potassium Bromid. (So- lution of Kali Bromid.) Potassium bromid gr. 183 Distilled water fl.oz. 4 — Homeopathic. This makes a ix solution. Dilutions: 2x is to be made from this with diluted alcohol; 3x is to be made with dispens- ing alcohol. See Dilutions, Homeo- pathic. Solution of Potassium Carbonate. Potassium carbonate av.oz. 10 Water fl.oz. 17^ Dissolve, filter, and dilute the liquid with water to the density of 1.330 to J-334- — Germ. Pharm. Solution of Potassium Chlorate. (So- lution of Kali Chlorate.) Potassium chlorate gr. 73 Distilled water fl.oz. 16 Mix and dissolve. — Homeopathic. This makes a 2x solution. Dilutions: 3x is to be made with diluted alcohol; 4x and higher are to be made with dis- pensing alcohol. See Dilutions, Homeo- pathic. Solution of Potassium Citrate. (Mix- ture of Potassium Citrate.) Potassium bicarbonate gr. 146 Citric acid gr. no Water, to make fl.oz. 4 Dissolve the bicarbonate and acid each in iH fluidounces of water, filter each separately, add enough water through each filter to make each filtrate measure 2 fluidounces, then mix the solutions, and when effervescence ceases transfer the liquid to a bottle.— U. S. P. This preparation should be freshly made when wanted. However, if the preparation is used very much, the two solutions (acid and bicarbonate) may be kept on hand and mixed as required. The product is an aqueous liquid con- taining about 9 per cent, of anhydrous potassium citrate, together with small amounts of citric and carbonic acids. If a similar solution of potassium citrate is desired without the two acids, it may be prepared extemporaneously by dis- solving 200 grains of potassium citrate PHARMACEUTICAL PREPARATIONS. 373 in enough distilled water to make 4 fluidounces. The preparation of the U. S. P. 1880, known as "mixture of potassium cit- rate," was similar to the above. See Mixture of Potassium Citrate. Solution of Potassium Dichromate. (Solution of Kali Bichromate.) Potassium bichromate gr. 183 Distilled water fl.oz. 4 — Homeopathic. This makes a ix solution, from which dilutions are to be made with distilled water. See Dilutions, Homeopathic. All preparations of this salt should be kept but a limited period of time. Solution of Potassium Permangan- ate. (Condy's Fluid — Liquor Kali Hypermanganici.) I. Potassium permanganate gr. 64 Distilled water fl.oz. 16 "Mix and dissolve. Preserve the solution in a glass or rubber-stoppered bottle. — U. S. P. 1870. II. Potassium permanganate gr. 73 Distilled water fl.oz. 16 — Brit. Pharm. III. Potassium permanganate. ..av.oz. 1 Distilled water fl.oz. 9 — Eclectic. Solution of Saccharin. Saccharin gr. 128 Sodium bicarbonate gr. 64 Alcohol fl.oz. 1 Water, to make fl.oz. 4 Dissolve the saccharin and the sodium bicarbonate in 2^2 fluidounces of water, filter the solution, add the alcohol to the filtrate, and pass enough water through the filter to make 4 fluidounces. This preparation is intended for sweetening liquids or solids when the use of sugar is objectionable or when a sweet taste is to be imparted to a liquid without increasing its density. It is sim- ilar to Elixir of Saccharin, which see. Solution (Salicylated) of Iron. See Solution of Iron, Salicylated. Solution, Salt or Saline, Normal or Physiological. (Therapeutic Salt Solution — Also called "Artificial Serum.") "Normal salt solution" is used for intravenous injection. When properly prepared it contains 0.6 to 0.75 per cent, of sodium chlorid, or 45 to 56 grains in 16 fluidounces of solution, the solvent being sterilized distilled water. Very frequently it is made from an even tea- spoonful of salt and 16 fluidounces of water. A good proportion, and one that should be adhered to, is a dram (60 gr.) to the pint. Drs. Locke and Hare have devised the following: Potassium chlorid gr. }£ Calcium chlorid gr. 2 Sodium chlorid gr. 65 Sterilized distilled water, to make fl.oz. 16 Before use, the solution should be warmed to 38 deg. C. The dose is 1 pint to 1 quart. Solution, Seller's. See Solution, Antiseptic, Seller's. Solution of Silver Nitrate. (Solution of Argentum Nitrate.) Homeopathic : ix is to be made with distilled water (46 grains to 1 fluidounce). See Solu- tions, Homeopathic. Dilutions are to be made from this with distilled water. See Dilutions, Ho- meopathic. Preparations of this salt should be kept in glass-stoppered bottles. Solution of Soap. See Soap, Surgical. Solution of Soda. (Solution of So- dium Hydroxid, U. S. P. 1900— Solution of Caustic Soda.) Soda (i. e., purified caustic soda) av.oz. 1 Distilled water, to make fl.oz. 16 The soda should be of the full strength (90 per cent.) and quality di- rected by the U. S. P. Soda of any oth- er strength, however, may be used if a proportionately larger or smaller quan- tity be taken. This solution should be kept in bottles 3T-A STANDARD FORMULARY OF made of green glass -and provided with glass stoppers coated with paraffin or petrolatum. — U. S. P. The product is an aqueous solution of sodium hydroxid containing about 5 per cent, of this compound. The prepara- tion of the Germ. Pharm. contains 15 per cent. In the U. S. P. 1890 this solution was directed to be prepared like Solution of Potassa (which see) by interaction be- tween lime (calcium oxid) and crystal sodium carbonate, using 375 grains of lime and 1,280 grains of pure crystal sodium carbonate to make 16 fluidounces of solution. Solution of Sodium Arsenate. Sodium arsenate, exsiccated, .gr. 20 Distilled water av.oz. 4^ Mix and dissolve. — U. S. P. The product is an aqueous solution containing not less than 1 per cent, of exsiccated sodium arsenate. In the U. S. P. 1890 this preparation was made up to a certain quantity by volume, viz., iS l / 2 grains of dried sodium arsenate and enough distilled water to make 4 fluidounces. This is also the formula of the Brit. Pharm. Solution of Sodium Arsenate, Fear- son's. Solution arsenate, perfect crystals gr. 12 Distilled water fl.oz. 16 Dissolve the sodium arsenate in the water, and filter, if necessary. This preparation may also be prepared as follows: Solution of sodium arsenate (U. S. P.) fl.oz. 1 Distilled water fl.oz. 9 Mix the solution of sodium arsenate with the water. This solution contains about 1/10 per cent, of anhydrous sodium arsenate, and each fluidram contains about 1/10 gr. of crystal sodium arsenate. This preparation should not be con- founded with the solution of sodium ar- senate U. S. P., which is ten times stronger than the above preparation. Pearson's Solution is recognized in the Codex, under the 'title Solute d'Arsen- ate de Soude (or Solution Arsenicale de Pearson). It is recommended that Pearson's Solution be dispensed only when expressly designated as "Pear- son's." — N. F. Solution of Sodium Borate, Com- pound. (DobelPs Solution.) Sodium borate gr. 240 Sodium bicarbonate gr. 240 Carbolic acid, crystallized. . . .gr. 48 Glycerin fl.dr. 9 Water, to make ..fl.oz. 32 Dissolve the salts in about 16 fluid- ounces of water, then add the glycerin, and the acid previously liquefied by warming, and lastly, enough water to make 32 fluidounces, and filter. — N. F. Solution of Sodium Carbolate or Phenate. I. Caustic soda (U. S. P.) gr. 22 Carbolic acid, crystal gr. 310 Water . fl.dr. 5 Dissolve the soda in the water, add the acid, and w T arm gently, until it is dissolved. This preparation should be made freshly when wanted for use, and should be preserved from the air. It is misci- ble in all proportions with water and alcohol. This formula is based upon that of the 1st Germ. Pharm. (is not in the present edition). II. What may sometimes be desired under the name "solution of sodium carbonate" or "phenol sodique" is the Codex preparation, which is as follows : Carbolic acid, crystal gr. 510 Caustic soda, pure gr. 220 Distilled water, to make... fl.oz. 16 Dissolve the soda in 10 fluidounces of the water, add the acid, mix well, and add the remainder of the water. This is much weaker than the pre- ceding. III. Still another preparation that may be desired under the name "phenol sodique" is the following (by Ber- inger) : PHARMACEUTICAL PREPARATIONS. 375 Coal tar av.oz. 2. .gr. 90 Caustic soda, pure gr. 120 Water, to make .fl.oz. 16 Dissolve the soda in 4 fluidounces of water, warm, add the tar and thorough- ly agitate for a few minutes. Then add the remainder of the water, set aside in a covered vessel in a warm place for several days, shaking frequently. De- cant and filter, washing the residue with enough water to bring the finished prep- aration to the measure of 16 fluidounces. Solution of Sodium Chlorid. (Solu- tion of Natrum Muriate.) Sodium chlorid, pure gr. 183 Distilled water fl.oz. 4 — Homeopathic. This makes a ix solution. Dilutions : 2x is to be made from this with distilled water; 3x is to be made with diluted alcohol; 4x and higher are to be made with dispensing alcohol. See Dilutions, Homeopathic. Solution of Sodium Citrate. (Mistura Sodii Citratis — Saturation — Potio Biveri — Saturatio — Saturatio Bi- veri — Biver's Potion or Draught.) Citric acid gr. 145 Sodium bicarbonate gr. 180 Distilled water fl.oz. 16 Dissolve the citric acid in the water contained in a bottle, add the sodium bicarbonate, in divided portions, dissolve it by agitation, and immediately stopper the bottle securely. This preparation should be freshly prepared when wanted for use. — N. F. The Germ. Pharm. directs that, when "Saturatio" is prescribed, without any specification of the ingredients or strength, Potio Riveri, represented here by the above, be dispensed. The directions of the Germ. Pharm. are to use 154 grains of citric acid to 16 fluidounces of distilled water and 346 grains pure sodium carbonate. Solution of Sodium Citro-Tartrate, Effervescent. (Tartro - Citric Lemonade — Effervescent Solution of Sodium Tartrate.) Sodium bicarbonate gr. 380 Tartaric acid gr. 350 Citric acid gr. 30 Syrup of citric acid fl.oz. 1^2 Water, to make fl.oz. 11^2 Dissolve 350 grains of sodium bicar- bonate in 8 fluidounces of water, add the two acids, and, when they are dis- solved, the syrup of citric acid. Filter the solution into a strong bottle of about 12 fluidounces capacity, and pass enough water through the filter to make the fil- trate measure 10V2 fluidounces. Dis- solve the remainder of the sodium bi- carbonate in 1 fl'uidounce of water, fil- ter the solution, pour it on top of the solution in the bottle, which close im- mediately with a cork, and secure it with twine. Then shake the bottle. — N. F. This is used as an efficient substitute for solution of magnesium citrate. The so-called "citrate of magnesia bottle" is to be used as a container for this preparation. Solution of Sodium Ethylate. Sodium metal, clean and bright gr. 23 Absolute alcohol fl.oz. 1 Cautiously dissolve the sodium in the alcohol contained in a flask, the latter being kept cool by a stream of cold wa- ter. The solution should be recently pre- pared, as it absorbs moisture from the atmosphere, which decomposes the com- pound C2H 5 ONa, of which it contains 18 per cent. — Brit. Pharm. It is used as a depilatory. Solution of Sodium Nitrate, Bade- macher's. (Saltpeter Tropfen — St. Peter's Tropfen.) Sodium nitrate, pure av.oz. 6 Distilled water fl.oz. iiY 2 — H. and D. While the above is known as "liquor natri nitrici," the following is given for "solutio natri nitrici Rademacheri" (in H.): Sodium nitrate gr. 120 Bismuth subnitrate gr. 15 Acacia av.oz. z /2 Distilled water fl.oz. 8 Solution of Sodium Oleate. Castile soap, white, dry and powdered gr. 480 Water, to make fl.oz, 16 376 STANDARD FORMULARY OF Mix the soap with 4 fluidounces of water so as to produce a uniform and gelatinous mixture. Then add \oy 2 fluid- ounces more of water, apply heat until the soap is dissolved, allow the liquid to cool and add enough water to make it measure 16 fluidounces. — N. F. This solution is intended to be used in the preparation of oleates. Solution of Sodium Phosphate, Comp. (Concentrated Solution of Sodi- um. Phosphate — Liquefied Sodium Phosphate — Solution of Sodium Citrico-Phosphate.) I. Sodium phosphate (selecting only transparent or unef- floresced crystals) av.oz. 16 Sodium nitrate gr. 280 Citric acid gr. 910 or av.oz. 2, gr. 35 Distilled water, to make. . .fl.oz. 15^2 Triturate the sodium phosphate and nitrate in a mortar with the citric acid until completely liquefied, then add enough water to make IS 1 A fluidounces, and filter.— N. F. Keep the solution in well-stoppered bottles in a moderately warm place. Most of the commercial concentrated solution of sodium phosphate contain sodium nitrate like the above ; the fol- lowing does not contain it. II. Sodium phosphate (select- ing only transparent crys- tals) av.oz. 16 Citric acid av.oz. 2> Z A Triturate together intimately, then heat gently on a water bath until lique- fied, and strain through a pellet of cot- ton if necessary. The above makes a total of about I2j^ fluidounces. — Cine. Acad. Pharm. Each fluidram of the liquid represents about 75 gr. of crystal sodium phos- phate and about 85 gr. of total solids. This preparation will crystallize at 15 deg. C, but will readily liquefy again on warming. It is miscible with water or syrup in all proportions. Solution of Sodium Salicylate. The following forms a 50 per cent. (1 gr. in 2 minims) aqueous solution which is convenient for dispensing pur- poses : Salicylic acid av.oz. 7^ Sodium bicarbonate av.oz. 4 J A Distilled water to make fl.oz. 16 Stir together until dissolved, and filter. Solution of Sodium Stearate. Edel's formula: Potassa (pure caustic pot- ash) gr. 143 Stearic acid, pure gr. 897 Alcohol fl.oz. 3 Distilled water to make. . . .fl.oz. 64 Dissolve the potassa in 1 fluidounce of alcohol, the acid in the remainder of the alcohol by the aid of a gentle heat, add- ing a little more alcohol if necessary, heat the potassa solution, add the acid solution, stir constantly till cool, and then add the water previously heated to about 80 deg. C. Solution of Strontium Bromid. A solution of this strength is used : Strontium bromid, pure gr. 480 Distilled water to make ... fl.oz. 8 Dissolve and filter. Solution of Strontium Lactate. A solution of this strength is used: Strontium lactate, pure gr. 480 Distilled water to make. . .fl.oz. 8 Dissolve and filter. Solution of Strychnine. Strychnine (alkaloid) gr. 4 Diluted hydrochloric acid .. sufficient Distilled water fl.dr. 10 Alcohol to make fl.dr. 20 Dissolve the strychnine in the water with the aid of a small amount of the acid, then add the alcohol. — Eclectic. See Solution of Strychnine Hydro- chlorid, which is similar. Solution of Strychnine Acetate. (Hall's Solution of Strychnine.) Strychnine acetate gr. 4 Diluted acetic acid (U. S. P.) fl.dr. 1 Alcohol fl.oz. 1 Compound tincture of car- damom m. 20 Distilled water, to make. . .fl.oz. 4 Dissolve the strychnine acetate in PHARMACEUTICAL PREPARATIONS. 377 about 2 fluidounces of water mixed with the acid, then add the alcohol, tincture, and lastly, enough water to make 4 fluidounces. Allow the mixture to stand a few days, if convenient, and filter. Each fluidram contains ]/§ gr. of strychnine acetate. — N. F. The Brit. Pharm. directs a Liquor Strychninae Hydrochloratis (with syno- nym : Liquor Strychnise) which is much stronger, and should not be confounded with the above preparation. It should never be dispensed, unless expressly designated. See Solution of Strychnine Hydrochlorid. Solution of Strychnine Hydrochlorid., (Liquor Strychniae — Solution of Strychnine.) Strychnine (alkaloid) gr. 18 Diluted hydrochloric acid. drops 36 Alcohol .fl.dr. 6 Distilled water fl.oz. 3 Dissolve the strychnine in the water with the aid of the acid, and then add the alcohol.— Brit. Pharm. 1885. The Brit. Pharm. 1898 directs 18 gr. of strychnine hydrochlorid, 1 fluidounce of alcohol, and 3 fluidounces of distilled water. See also Solution of Strychnine. Each fluidram contains 3/5 gr. of strychnine. See also Solution of Strychnine Ace- tate. Solution of Strychnine Nitrate. Strychnine (alkaloid) gr. 16 Nitric acid m. 25 Distilled water fl.oz. 4 Mix and agitate until dissolved. — Ec- lectic. Solution of Sulfurated Lime. ( Solu- tion of Sulfuret of Lime — Solu- tion of Oxysulfuret of Calcium — Vleminck's Solution or Lotion.) Lime, freshly slaked av.oz. 2 Sublimed sulfur av.oz. 3 Water, to make av.oz. 12 Mix the slaked lime with the sulfur, and add the mixture gradually to 20 fluidounces of boiling water. Then boil the whole, under constant stirring, until it is reduced to 12 av.ounces, strain, and having allowed the solution to become clear by standing in a well-stoppered bottle, decant the clear brown liquid, and keep it in completely filled and well- stoppered bottles. — N. F. Solution of Tar, Alkaline. (Bulkley's Solution of Tar.) Pine tar av.oz. 4 Caustic potassa av.oz. 2 Water fl.oz. 9 Dissolve the potassa in the water. Shake the solution with the tar so that the latter may be dissolved, and strain the solution through muslin. — N. F. Solution of Thymol. Thymol gr. 8 Alcohol fl.dr. iy 2 Glycerin fl.dr. 2 l / 2 Water to make fl.oz. 16 Dissolve the thymol in the alcohol, add the other ingredients, and filter. — Eclectic. Solution, Thyroid. (Liquor Thyroi- dei.) Remove the external fat and con- nective tissue from thyroid glands taken from sheep immediately after killing; cut the glands across, and reject any that contain cysts, are hypertrophied, or are otherwise abnor- mal ; count the healthy glands that re- main; slice them and bruise them thor- oughly in a mortar; for each entire gland (consisting of two lobes), add 33 minims of glycerin and 33 minims of y 2 per cent, solution of carbolic acid in dis- tilled water, transfer the mixture, well stirred, to a flask, and close the neck of the latter with a plug of cotton; allow to stand for 24 hours; strain through linen, with strong pressure; and add to the strained liquid enough of a ^ per cent, solution of carbolic acid in dis- tilled water to make 96 minims of solu- tion for each gland used. — Brit. Pharm. The product is a pinkish, turbid liquid entirely free from any odor of putres- cence. It must be freshly prepared and kept in well-stoppered, sterilized bottles, Dose, 5 to 15 minims. 0*/Q U I o STANDARD FORMULARY OF Solution, Anodyne, Turpentine, Rad- emacher's. Spirit of ether fl.oz. I2>4 Oil of turpentine, rectified, .fl.oz. i — H. Solution, Villate's. (Astringent and Escharotic Mixture.) Solution of lead subacetate.fi. dr. 12 Copper sulfate gr. 480 Zinc sulfate gr. 480 Diluted acetic acid fl.oz. 14 Dissolve the copper and zinc sulfates ■in the acid, add the solution of lead sub- acetate, and agitate thoroughly. Set the mixture aside, so that the precipi- tate may subside. Then decant, or siphon off, the clear liquid and preserve it for use. In attempting to pass the liquid through a filter, it will usually be found that the finely divided precipitate of lead sulfate will partially pass along with it. This may be prevented (in this and many similar cases) by adding to the mixture a small quantity of starch, thoroughly incorporating this by agitation, and pouring the mixture on the previously wetted filter. The first portions of the filtrate are poured back until it runs through clear. — N. F. Solution of Zinc and Aluminum, Compound. Zinc sulfate av.oz. 14 Aluminum sulfate av.oz. 14 Betanaphthol gr. 18 Oil of thyme fl.dr. 1 Water, to make gall. y 2 Dissolve the zinc and aluminum sul- fates in */2 gallon of water, by the aid of heat, add the naphthol and oil, and shake the mixture occasionally, in a stoppered bottle, until it cools. Set it aside for a few days, if convenient, and then pass it through a wetted filter, fol- lowing it with enough water to make Vz gallon.— N. F. The commercial aluminum sulfate (not alum) may be used for this prep- aration. This generally contains a trace of iron, but by allowing the liquid to stand, this will be gradually precipi- tated, See Solution of Zinc and Iron, Com- pound. Solution of Zinc Chlorid. (Burnett's Disinfecting Fluid,) I. Zinc, granulated av.oz. 6 Hydrochloric acid, .av.oz. 21 or fl.oz. 17K Nitric acid gr. 132 or m. 100 Zinc carbonate, precipitated.gr. 132 Distilled water sufficient To the zinc, contained in a glass or porcelain vessel, add 4 fluidounces of distilled water, then gradually add the hydrochloric acid, and digest until re- action ceases and the acid is saturated or refuses to dissolve any more of the metal. Pour off the solution, add the nitric acid, evaporate the solution to dryness, and heat the dry mass to fusion at a temperature not exceeding 115 deg. C. Let it cool, and dissolve it in a sufficient amount of distilled water to make the product weigh 25 av.ounces (measuring about 16 fluidounces). Then add the zinc carbonate, agitate the mix- ture occasionally during 24 hours, and then set it aside until it has become clear by subsidence. Finally, separate the clear solution by decantation or by means of a siphon. — U. S. P. The product is an aqueous solution of zinc chlorid, containing about 5° P er cent, by weight of the salt. This preparation is practically identi- cal with Burnett's disinfecting fluid, al- though the latter is really about 1/3 stronger. II. Zinc, granulated av.oz. 6^4 Hydrochloric acid fl.oz. 18 Zinc carbonate, Chlorin water. Distilled water, each sufficient Mix the acid with 8 fluidounces of water in a porcelain dish, add the zinc, apply a gentle heat until gas is no longer evolved, boil for half an hour, supplying the water lost by evaporation, and allow to cool. Test the product for iron and lead. If either be present, PHARMACEUTICAL PREPARATIONS. 379 filter the solution into a bottle and add chlorin water, little by little, with fre- quent agitation, until the liquid acquires a permanent odor of chlorin; add zinc carbonate in small quantities at a time, with renewed agitation, until a brown sediment appears and the whole of the lead or iron is thus precipitated; filter the liquid, and evaporate to 16 fluid- ounces. — Brit. Pharm. If no iron or lead be present in the liquid, filter the cooled product and evaporate it to 16 fluidounces. Solution of Zinc and Iron, Compound. (Deodorant Solution.) Zinc sulfate av.oz. 14 Ferrous sulfate av.oz. 14 Copper sulfate av.oz. 4^ Betanaphthol gr. 18 Oil of thyme fl.dr. 1 Hypophosphorous acid, 30 per cent fl.dr. 2 Water, to make .....gall. x / 2 Dissolve the zinc, ferrous and copper sulfates in 50 fluidounces of boiling water, add the naphthol and oil, and shake the mixture occasionally, in a stoppered bottle, until it is cold. Then add the acid, filter the liquid through a wetted filter, and lastly, pass enough water through the filter to make H gal- lon.— N. F. This solution is used as a simple de- odorant and antiseptic for common do- mestic use, when it is unnecessary or impracticable to employ more powerful agents. When a deodorant solution is re- quired for purposes where iron is ob- jectionable, as for instance, when woven fabrics are to be steeped in it, Solution of Zinc and Aluminum, Compound, may be employed (which see). Species. ("Teas" — Thee-Kraeuter — Theegemische.) Species, commonly known as "teas," are mixtures of crude drugs in a coarse- ly comminuted state, The drugs must not be in large pieces nor must any fine powder be present; Species, Alterative. (Swedish Blood- Purifying' Tea — Compound Spe- cies of Guaiac — Species ad Decoc- tum Lignorum.) Licorice root, cut av.oz. 1 Saponaria, cut av.oz. 2 Juniper wood, rasped av.oz. 4 Guaiacum wood, rasped. .. .av.oz. 6 — Swed. Pharm. See also Species, Wood. Species, Aromatic. (Aromatic Tea — Species Resolventes — Gewuerz- hafte Kraeuter.) Peppermint, cut fine parts 2 Wild thyme, cut fine parts 2 Garden thyme, cut fine. ... .parts 2 Lavender flower . .parts 2 Clove, cut fine part 1 ., , Cubeb, coarse powder part 1 — Germ. Pharm. Species, Bitter. (Bitter Tea.) I. Wormwood, cut parts 2 European centaury, cut... parts 2 Bitter orange peel, cut.... parts 2 Buckbean, cut part 1 Calamus, cut part 1 Gentian, cut .part 1 Cassia bark, cut part 3/10 — Austr. Pharm. II. Guaiac wood, Juniper berries, Buckbean leaves, Senna, each equal parts — Norw. Pharm. III. Juniper berries. Buchu, Senna, each equal parts — Dan. Pharm. IV. The Swed. Pharm. has what it calls Boecker's Bitter Tea, also called Species Quassise Amarae, which is pre- pared as follows : Star-anise, crushed part 1 Quassia, rasped parts 2 Blessed thistle, cut parts 2 Species, Diuretic. (Diuretic Tea — Harntreibender Thee.) I. Lovage root, cut, Restharrow root, cut, Licorice root, cut, Juniper berries, crushed, each equal parts —Germ. Pharm. 380 STANDARD FORMULARY OF II. An older formula is this: Licorice root, cut parts 4 Lovage root, cut parts 3 Rest harrow root, cut parts 3 Pansy herb, cut parts 3 Juniper berries, crushed. .. .parts 3 Parsley seed parts 2 Anise seed parts 2 — D. Species, Emollient. (Emollient Cata- plasm — Erweichende Kraeuter.) Althea leaves, Mallow leaves, Melilot tops, German chamomile, Flaxseed, each equal parts Reduce them to a coarse powder, and mix it uniformly. Mallow leaves are derived from Malva vulgaris Fries and Malva sylves- tris Linne. Melilot tops are the leaves and flowering branches of Melilotus offi- cinalis Desrousseaux, and Melilotus altissimus Thilliers. — N. F. and Germ. Pharm. Species, Juniper. (Juniper Tea — En- ebaer The.) Anise seed part 1 Licorice root part 1 Juniper berries parts 8 — Norw. Pharm. Species, Laxative. (St. Germain Tea — Species Laxantes — Laxative Tea.) I. Senna, cut av.oz. 8 Elder flowers av.oz. 5 Fennel, bruised av.oz. 2^2 Anise, bruised av.oz. 2H Potassium bitartrate, fine powder av.oz. 2 Moisten the senna with a small quan- tity of water ; then sprinkle over it, as uniformly as possible, the potassium bitartrate. When it has become dry, mix it lightly and uniformly with the other ingredients.— N. F., Germ. Pharm. (2nd) and Dan. Pharm. The present Germ. Pharm. directs that the bruised anise and fennel be moistened with a solution of i]4 av.- ounces of potassium tartrate in 2V2 fluidounces of water; in one-half hour, moisten them with a solution of }i av. ounce of tartaric acid in 6 fluidrams of water, dry, and add the elder and senna. II. The Norw. and Dan. (not the Swed.) Pharms. both recognize a "laxa- tive species," also called "Hamburg tea." The former directs this mixture: Senna, cut parts 60 Manna parts 25 Coriander, crushed parts 8 Potassium bitartrate, pow- der parts 7 x / 2 Mix the potassium bitartrate intimate- ly with the manna and add the other ingredients. The Dan. Pharm. directs a mixture of Senna parts 62>4 Manna parts 25 Coriander parts 7^2 Potassium bitartrate parts 5 The Dan. Pharm. also has the Laxa- tive Species or Species St. Germain. See No. I. Species, Long Life. (Species ad Long-am Vitam.) Aloes parts 4 Rhubarb part 1 Gentian part 1 Zedoary part 1 Galangal part 1 Myrrh part 1 Agaric part 1 Spanish saffron part 1 Theriac part 1 Reduce the first seven ingredients to small pieces, then rub the agaric to coarse powder, triturate the theriac with it and mix the whole. — H. Species, Marshmallow. (Marshmal- low Tea. — Species Althea.) Marshmallow root, cut parts 10 Marshmallow leaves, cut... parts 5 Licorice root, cut parts 2J/2 Mallow flowers (Malva syl- vestris), cut part 1 — Austr. Pharm. Species, Pectoral. (Breast Tea — Brust Thee — Bryst The — Species ad Infusum Pectorale.) Althea root, peeled parts 8 Coltsfoot leaves parts 4 Licorice root, Russian, peeled parts 3 Anise parts 2 Mullein flowers parts 2 Orris root part 1 Cut, bruise and mix them. Pectoral Infusion, or Infusion of Pec- toral Species, js made by infusing 480 PHARMACEUTICAL PREPARATIONS. 381 grains of the above preparation, in the usual manner, so as to obtain 10 fluid- ounces of strained product. — N. F. and Germ. Pharm. II. Marshmallow leaves parts 40 Licorice root parts 30 Marshmallow root parts 10 Barley parts 10 Mullein flowers part 1 Mallow flowers part 1 Red poppy petals part 1 Star anise part 1 — Austr. Pharm. III. Anise seed parts 2 Elder flowers parts 3 Coltsfoot parts 3 Licorice root parts 6 Althea root parts 6 — Norw. Pharm. Species, Wood. (Species Lignoruxn — Wood Tea — Blood-Purifying Tea — Blutreinigung Thee — Holz Thee.) Guaiac wood parts 5 Rest harrow parts 3 Licorice root part 1 Sassafras wood part 1 Cut into coarse pieces and mix well. — Germ. Pharm. See also Species, Alterative. Spirits. ("Essences.") The spirits of the U. S. P. are simply alcoholic solutions of volatile substances, such as volatile oils, camphor, etc. Many of them are known "commonly as essences, although the latter term is also applied to some other preparations. According to the N. F., any spirit or alcoholic solution of a volatile oil, for which no formula is given by the U. S. P., N. F. or otlier standard work, should be prepared in accordance with the following general formula : Volatile oil fl.oz. 1 Deodorized alcohol fl.oz. 15 Dissolve the oil in the alcohol. The strength of the spirit thus pre- pared is approximately 5 per cent, by weight, provided the specific gravity of the oil is in the neighborhood of 0.900, as is the case with the majority of volatile oils, Spirit of (Bitter) Almond. ( Essence of Bitter Almond.) Oil of bitter almond m. 80 Alcohol . T fl.oz. 123^ Distilled water to make fl.oz. 16 Dissolve the oil in the alcohol and add the water.— U. S. P. Spirit of Ammonia. (Dzondi's Spirit — Ammoniated Alcohol.) Stronger (28 p. c. or so- called "concentrated") am- monia water fl.oz. 8 Alcohol sufficient Pour the ammonia water into a flask provided with a safety funnel tube and connected with a glass condenser, the latter in turn to be connected with a well-cooled receiver containing 16 fluid- ounces of alcohol, the delivery tube of the condenser reaching to near the bot- tom of the receiver. Heat the flask carefully, and very gradually, to a tem- perature not exceeding 60 deg. C. and maintain it at that temperature until ammonia ceases to be evolved. Then disconnect the receiver and having as- certained the ammonia strength of the contents by the assay process, add enough alcohol to make the product contain 10 per cent, by weight of am- monia gas. Keep the product in glass-stoppered bottles in a cool place. The solution deteriorates and should be tested fre- quently. The alcohol for this preparation should have been recently distilled and, after distillation, kept in glass vessels. Spirit of Ammonia, Aromatic. (Com- pound Spirit of Ammonia — Spirit of Sal Volatile.) I. Ammonium carbonate, in hard, translucent pieces (not the white powder) .. .gr. 250 Ammonia water, 10 p. c. . . .fl.oz. i l / 2 Oil of lemon fl.dr. 1 % Oil of lavender flowers. . . . . .m. 8 (about drops 12) Oil of nutmeg m. 8 (about drops 12) Alcohol fl.oz. 11 Distilled water, to make. . .fl.oz. 16 To the ammonia water, contained in a flask or bottle, add 2V2 fluidounces ot 382 STANDARD FORMULARY OF water, and afterwards the ammonium carbonate reduced to moderately fine powder. Close the vessel and agitate the contents frequently until the salt is dissolved. Put the alcohol into another vessel, add the oils, then gradually add the solution of ammonium carbonate, and afterwards enough distilled water to make the product measure 16 fluid- ounces. Set the liquid aside during 24 hours in a cool place, occasionally agi- tating, then filter it through paper in a well-covered funnel. — U. S. P. Keep the product in glass-stoppered bottles in a cool place. It is best to let the mixture of am- monia water, ammonium carbonate and water stand for 24 hours before adding to the oil and alcohol mixture. II. Ammonium carbonate, trans- lucent pieces gr. 184 Strong solut'n of ammonia. fl. dr. 63^ Oil of nutmeg m. 27 Oil of lemon m. 40 Alcohol fl.oz. 12 Distilled water fl.oz. 6 Place the two oils with the alcohol and distilled water in a retort; distil 14 fluidounces ; then distil and separate- ly collect an additional 7 fluidrams. Place the latter, together with the am- monium carbonate and the solution of ammonia, in a bottle holding rather more than 2 fluidounces, securely cork the bottle, and gently warm in a water bath to 60 deg. C, shaking from time to time until all the salt is dissolved. Filter the solution, when cold, through a pledget of cotton, and gradually mix the filtrate with the portion first distilled. Spirit of Ammonia* Anisated. Anethol fl.dr. 4 Ammonia water fl.oz. 3 Alcohol, q. s. Dissolve the anethol in a portion of the alcohol, add the ammonia water and alcohol to make 16 fluid ounces. — N. F. Spirit of Ammonia, Fetid. Asafetida av.bz. 1*4 Stronger ammonia water, 28 p. c fl.dr. 15 Alcohol, to make fl.oz, 16 Break the asafetida into small pieces, macerate in a closed vessel with 12 fluid- ounces of alcohol for 24 hours, distil until alc.oholic vapors cease to be con- densed, mix the distillate with the am- monia water, and add the remainder of the alcohol. — Brit. Pharm. Spirit of Angelica, Compound. I. Angelica root, cut moderate- ly fine av.oz. 2. .gr. 145 Valerian, cut moderately finc.gr. 250 Juniper berries, bruised gr. 250 Alcohol fl.oz. 13 Water fl.oz. 18 Camphor gr. 125 Macerate the roots and berries in the alcohol and water for 24 hours, agitating occasionally, then distil off 16 fluid- ounces, and dissolve the camphor in the distillate. — Germ. Pharm. II. A simple formula is the following: Oil of angelica root m. 15 Oil of valerian m. 5 Oil of juniper berries m. 5 Camphor gr. 150 Water fl.oz. 4 Alcohol fl.oz. 12 — H. Spirit of Anise. Oil of anise fl.dr. 13 Deodorized alcohol, to make. fl.oz. 16 — U. S. P. and Brit. Pharm. The spirit of anise, Brit. Pharm., is one-half the strength of the essence of anise of the Brit. Pharm. 1885. Spirit, Apoplectic. (Slagvatten.) This is a Scandinavian preparation made by distilling equal parts of rose- mary and lavender flowers with dilute alcohol. Ordinarily spirit of lavender, which see, is dispensed. The gold leaf formerly added to it is not considered necessary. Spirit, Aromatic. Compound spirit of orange, .fl.oz. 1 Alcohol fl.oz. 15 Preserve the product, if it is to be kept in stock, in completely filled and well-stoppered vials or bottles, and stored in a cool and dark place. Aromatic spirit may also be prepared in this manner; PHARMACEUTICAL PREPARATIONS. 383 Sweet orange peel, fresh and deprived of the white, in- ner portion av.oz. ^A Lemon peel, fresh gr. 240 Coriander, bruised gr. 240 Oil of star anise m. 5 Alcohol, to make fl.oz. 32 Macerate the solids during 4 days with 29 fluidounces of alcohol, then add the oil of star anise, filter, and pass enough alcohol through the filter to make the product measure 32 fluidounces. When good, fresh essential oils can- not be readily obtained for preparing this spirit, the second formula may be used. But the product obtained by it should not be employed in mixtures con- taining iron, as the latter would cause a darkening of the mixture. — N. F. Spirit of Cajuput. Oil of cajuput fl.dr. 13 Alcohol, to make fl.oz. 16 —Brit. Pharm. This preparation is 5 times the strength of the same preparation of the Brit. Pharm. 1885. Spirit of Camphor. (Tincture of Camphor, TJ. S. P. 1850.) Camphor av.oz. s l A Alcohol, to make fl.oz. 32 Dissolve the camphor in 12 fluid- ounces of alcohol, filter through paper, and pass the remainder of the alcohol through the filter.— U. S. P. and Brit. Pharm. The formula of the U. S. P. 1880 {which is the formula of the Germ. Pharm.) directed 3 av.ounces of cam- phor, 24 fluidounces of alcohol and 6 fluidounces of water, the camphor to be dissolved in the alcohol, the water added, and the whole filtered. The latter will serve for ordinary counter sales, but when the spirit is to be mixed in liniments with oils, chloro- form, etc., the U. S. P. 1900 formula must be used, as it only makes a clear mixture. - The corresponding Eclectic and ho- meopathic preparations are called tinc- ture of camphor ; see Tincture of Cam- phor. Spirit of Caraway. (Tincture of Oil of Caraway — Essence of Cara- way.) Oil of caraway fl.oz. 1 Alcohol fl.oz. 1 1 — Eclectic. Spirit of Cardamom, Compound. Oil of cardamom fl.oz. \ x / 2 Oil of orange fl.oz. \ l / 2 Oil of cinnamon, Cassia m. 72 Oil of clove m. 36 Anethol m. 36 Oil caraway m. 4 Acohol, to make fl.oz. 16 Dissolve the oils in the alcohol, add- ing enough to make 16 fluid ounces. This preparation is intended as a fla- voring ingredient, being equivalent to the official compound tincture of carda- mom without the coloring matter. — N. F. Spirit of Chloroform ("Chloric Ether" — Spirit of Chloric Ether.) I. Chloroform fl.oz. 1 Alcohol . fl.oz. isV\ — U. S. P. The name "chloric ether" is often ap- plied to this mixture. II. Chloroform fl.dr. 6^ Alcohol, to make fl.oz. 16 —Brit. Pharm. III. A mixture of 1 volume of chlo- roform and 2 of alcohol has been called "concentrated chloric ether." Spirit of Cinnamon. Oil of cinnamon fl.dr. 13 Alcohol, to make fl.oz. 16 — U. S. P. and Brit. Pharm. The preparation of the present Brit. Pharm. is 5 times the strength of the Brit. Pharm. of 1885. Spirit of Curacao. Oil of Curagao orange fl.oz. 2]/ 2 Oil of fennel m. 25 Oil of bitter almond m. 6 Deodorized alcohol, to make. fl.oz. 16 Mix the oils with the alcohol, and keep the spirit in completely-filled and well- corked bottles, and stored in a cool and dark place. The essential oils used in this case must be as fresh as possible, and abso- 384 STANDARD FORMULARY OF lutely free from any terebinthinate odor or taste. Oil of Curasao orange may be obtained without difficulty in the mar- ket, but it should be carefully examined as to its quality, immediately upon re- ceipt, and should not be kept in stock, for any length of time, without special precautions. A still finer quality of oil of orange is that derived from Citrus nobilis, which is known in the market as oil of mandarin. Spirit of Ether. (Spiritus JEtheris — Hoffmann's Drops — Liquor Ano- dynie Mineralis Hoffmanni.) Stronger ether fl.oz. s J A Alcohol fl.oz. io^4 — U. S. P. The ordinary (not "stronger") ether may be used if desired, if it be mixed in the proportion of 6^4 fluidounces with 9l4 fluidounces of alcohol. The above is the preparation common- ly sold as Hoffmann's Drops and rec- ognized by German works under this name. The Brit. Pharm. directs mixing I volume of stronger ether with 2 vol- umes of alcohol. The Germ, and Austr. Pharms. direct I part by weight of stronger ether to 3 parts of alcohol, which is equivalent to 4J/2 fluidounces of the former to 11 24 of the latter. Spirit of Ether, Camphorated. (Kam- fer Draaber — Camphor Drops — Nerve Drops — Nerf Drofpar.) Norw. and Dan. Pharms. : Camphor av.oz. 3 Stronger ether fl.oz. 5 Alcohol fl.oz. 15 Spirit of Ether, Compound. (Hoff- mann's Anodyne.) I. Stronger ether fl.oz. 5 Alcohol fl.oz. 10 Ethereal oil fl.dr. 3 — N. F. Or mix ordinary (so-called U. S. P. 1880) ether, 6 l / 2 fluidounces, Sy 2 fluid- ounces of alcohol and 3 fluidrams of ethereal oil. The Hoffmann's anodyne of the mar- ket is an uncertain preparation obtained in the redistillation of crude sulfuric ether and subsequently more or less altered by the addition of alcohol, ether, etc. II. Stronger ether fl.oz. 2 l A Alcohol fl.oz. 39 Sulfuric acid fl.oz. 17 Distilled water fl.dr. 6 Sodium bicarbonate sufficient Gradually mix the acid with 20 fluid- ounces of alcohol, let stand 24 hours, then distil slowly until a thermometer, the bulb of which is within the liquid, indicates a temperature of 171 deg. C. Pour the distillate into a separator, and after separation is complete, remove the lower layer. Add the distilled water to the upper layer and also gradually so- dium bicarbonate until, after agitation, the liquid is nearly neutral to litmus paper. Separate the ethereal liquid and add to it the ether and 19 fluidounces of alcohol. — Brit. Pharm. Spirit of Formic Acid. (Spiritus Formicarum — Spirit of Ants — — Ameisen Spiritus or Geist.) Formic acid fl.dr. 4 Distilled water fl.oz. 2^/2 Alcohol, to make . .fl.oz. 16 Mix the formic acid with the distilled water, and add the alcohol. — N. F. Formic acid for this preparation should have a specific gravity of 1.060 to 1.063, or containing 25 per cent, of abso- lute formic acid. The formula of the Germ. Pharm. is practically identical with the above. Spirit of Horse-Radish, Compound. (Spiritus Armoraciae Compos- itus.) Horseradish root, fresh, scraped av.oz. 2 Bitter orange peel, cut small and well bruised av.oz. 2 Nutmeg, bruised gr. 22 Alcohol fl.oz. 10 Distilled water fl.oz. 12 Mix and distil 16 fluidounces. — Brit. Pharm. Spirit of Juniper. Oil of juniper berries fl.oz. 1 Alcohol fl.oz. 19 — U. S. P. and Brit. Pharm. The preparation of the Brit. Pharm. is 2^ times the strength of the Brit. Pharm. of 1885. PHARMACEUTICAL PREPARATIONS. 385 The Germ. Pharm. directs mixing 4 av.ounces of crushed juniper berries, 14 fluidounces of alcohol and ii^ of water, macerating for 24 hours at a tempera- ture of 15 to 20 deg. G, occasionally agitating, and distilling off 17 av.ounces. Spirit of Juniper, Compound. Oil of junioer berries fl.dr. 1 Oil of caraway m. 8 (about drops 12) Oil of fennel m. 8 (about drops 12) Alcohol fl.oz. 22.y 2 Water, to make. fl.oz. $2 Dissolve the oils in the alcohol, and gradually add the water. — U. S. P. This is used as a substitute for Hol- land gin. Spirit of Lavender. Oil of lavender flowers fl.oz. 1 Deodorized alcohol fl.oz. 19 The preparation of the Brit. Pharm. is 2 times the strength- of the above and is 5 times the strength of that of the Brit. Pharm. of 1885.— U. S. P. The Germ. Pharm. directs mixing 4 av.ounces of lavender flowers, 14 fluid- ounces of alcohol and 11 3*4 of water, macerating for 24 hours at a tempera- ture of 15 to 20 deg. C., occasionally agitating, and distilling off 17 fluid- ounces. Spirit of Lemon. (Essence of Lem- on — Spiritus Citri or Limonis.) Oil of lemon fl.oz. 1 Lemon peel av.oz. 1 Deodorized alcohol, to make.fl.oz. 20 Dissolve the oil in 18 fluidounces of the alcohol, add the lemon peel, macer- ate for 24 hours, agitating occasionally, filter, and through the filter add enough deodorized alcohol to make the filtrate measure 20 fluid ounces.— N. F. Ill, and U. S. P. 1890. The oil of lemon should be pure and perfectly free from terebinthinate odor, and the lemon peel should have been freshly grated from the fruit. Spirit of Mastic, Compound. (Spirit- us Matricalis — Mutter Spiritus.) Mastic av.oz. 34 Olibanum av.oz. 24 Myrrh av.oz. y A Alcohol fl.oz. 16 Water fl.oz. 4^ Macerate the contused drugs with the mixed alcohol and water for 24 hours, and distil 16 fluidounces. — H. modified. Spirit of Melissa. (Spirit of Balm — Melissen Geist.) This may be prepared by distilling 4 av.ounces of melissa herb with 14 fluid- ounces of alcohol and 20 of water, so as to obtain 16 fluidounces of product. — D. modified. It may also be prepared by dissolving 24 drops of oil of melissa in 12 fluid- ounces of alcohol and adding 4 fluid- ounces of water. Spirit of Melissa, Compound. (White Mother Drops — Carmelite Spirit — Karmeliter Geist — Eau de Me- lisse de Carmes.) I. Melissa herb gr. 465 Lemon peel gr. 400 Nutmeg gr. 200 Cassia cinnamon gr. 100 Clove gr. 100 Alcohol fl.oz. 13 Water fl.oz. 18 Mix all and distil off 16 fluidounces.— Germ. Pharm. II. A quicker and more convenient proc- ess is this: Oil of melissa, true m. 20 Oil of lemon m. 20 Oil of nutmeg m. 15 Oil of clove ; m. 15 Oil of cassia*. m. 15 Water fl.oz. 1 Alcohol, to make fl.oz. 16 — H. Spirit of Mustard. (Spiritus Sinapis.) Volatile oil of mustard fl.dr. 2^2 Alcohol, to make fl.oz. 16 Or mix in the proportion of 1 part by weight of oil to 49 of alcohol. — N. F. and Germ. Pharm. Spirit of Nitroglycerin. (Spirit of Glonoin or Trinitrin — Solution of Trinitrin or Nitroglycerin, Brit. Pharm.) Owing to the highly dangerous char- acter of nitroglycerin, this preparation is never made by the pharmacist, but always purchased by him in the form of 386 STANDARD FORMULARY OF a more or less dilute alcoholic solution. The spirit of nitroglycerin is described by the U. S. P. as "an alcoholic solution of glonoin or nitroglycerin (glyceryl or propenyl trinitrate) containing I per cent., by weight, of the substance." The spirit should be kept and trans- ported in well-stoppered tin cans, and should be stored in a cool place, remote from lights or fire. The preparation of the Brit. Pharm. is of the same strength as that of the U. S. P. See also the homeopathic Tincture of Glonoin. Great care should be exercised in dis- pensing, handling, packing, transporting and storing the spirit, as a dangerous explosion may result if any consider- able quantity be spilled and the alcohol be partially or wholly lost by evapora- tion. In case of spilling of the spirit, pour over it at once some solution of potassa, which quickly causes decomposition of the nitroglycerin. An expert on explo- sives advises pouring on the spilled spirit some solution of sodium sulfocar- bonate prepared by boiling sulfur with aqueous solution of sodium carbonate. Spirit of Nitrous Ether. (Sweet Spirit of Nitre — Spiritus Nitri Dulcis.) I. Sodium nitrite av.oz. 2^2 Sulfuric acid av.oz. 1 Sodium carbonate, monohy- drated gr. 7 Potassium carbonate, com- pletely deprived of water by drying gr. 35 Alcohol, water, each sufficient Mix the acid with 3 fluidounces of water, cool the liquid, add 2 fluidounces and 1 fluidram of alcohol previously diluted with the same amount of water and introduce the mixture into a flask, holding not less than 25 fluidounces, sur- rounded by a mixture of ice and water. Dissolve the sodium nitrite in 7 fluid- ounces of water, filter, and, having poured the filtrate into a separating fun- nel, allow the liquid to drop slowly into the flask containing the acid mixture. When all has been added and the reac- tion is complete, allow any crystals which may have formed to settle at the bottom of the flask and decant the cold mixture of ethyl nitrite and aqueous solution quickly to the previously cleaned separatory funnel and draw off and dis- card the aqueous liquid. Wash the sep- arated ethyl nitrite first with 4 fluid- drams of ice-cold water, and then re- move any traces of acid by washing it with 3 fluidrams of ice-cold water con- taining the sodium carbonate in solution. Carefully separate the ethyl nitrite from the aqueous liquid and agitate it in a well-stoppered vial with the potassium carbonate to remove traces of water. Then cool the liquid, decant it, and pour the ethyl nitrite immediately into a tared bottle 12^2 av.ounces of alcohol. -Ascer- tain the weight of the ethyl nitrite poured into the alcohol by noting the increase in the weight of the tared bot- tle and contents and then add enough alcohol to make the mixture weigh 22 times the weight of the ethyl nitrite added. Lastly, transfer the product to small, well-stoppered amber-colored vials, and keep these in a cool place, remote from lights or fire. — U. S. P. While the U. S. P. does not distinctly specify it, distilled water only should be used in making this preparation. This process is an entirely new one, as in all previous editions of the U. S. P. and in all other pharmacopeias, this preparation is made by distillation. Spirit of nitrous ether should contain not less than 4 per cent, by weight of ethyl nitrite. Commercial sweet spirit of nitre, es- pecially such as is obtained in large quantities as in carboys, is of very in- ferior quality. It contains water which hastens decomposition and it is always more or less exposed to light and air, which are both prejudicial. A better ar- ticle can be made from the commercial ethyl nitrite, or so-called "concentrated nitrous ether," which is usually stated to contain 90 per cent, of absolute ethyl PHARMACEUTICAL PREPARATIONS. 387 nitrite. This is to be mixed with 19 times its weight or 21 times its volume of alcohol, to make sweet spirit of nitre. The ethyl nitrite must, however, be quite fresh, as it soon decomposes. II. Nitric acid _ fl.oz. i l / 2 Sulfuric acid fl.oz. 1 Copper, fine wire av.oz. 1 Alcohol sufficient To 10 fluidounces of the alcohol, add gradually the sulfuric acid, stirring them together; then stir in i l /i fluidounces of the nitric acid, the mixture being made in a retort or flask in which the copper has been placed, to which is fit- ted a thermometer, and to which is at- tached an efficient condenser and re- ceiver, the latter containing 10 fluid- ounces of alcohol; apply heat gently; distil at a temperature commencing at 76 deg. C. and rising to 80 deg. C, but not exceeding 82 deg. C, until the vol- ume of the liquid in the receiver has been increased to 16 fluidounces, the receiver and condenser being kept cool with ice-cold water. Then withdraw the source of heat, and having allowed the contents of the retort to cool, intro- duce the remaining 2 fluidrams of nitric acid, and resume distillation as before, until the liquid in the receiver has in- creased to 17 fluidounces. Mix this liquid with 10 fluidounces of alcohol, or as much as will make the product con- tain 2^ p. c. of ethyl nitrite. — Brit. Pharm. The U. S. P. process is superior to that of the Brit. Pharm. It will be observed that the U. S. P. preparation is to contain 4 p. c. of ethyl nitrite, while that of the Brit, is to con- tain but 2 X A p. c. The Brit. Pharm. also recognizes a Solution of Ethyl Nitrite which is a mixture of 1 volume of glycerin with 19 of absolute alcohol, containing when freshly made 3 p. c. by weight of ethyl nitrite, and even when long kept not less than 2}/ 2 p. c. by weight of ethyl nitrite. The latter is to be obtained by the inter- action of alcohol, sodium nitrite and di- luted sulfuric acid, at a low temperature ; but no process is given. III. Alcohol av.oz. 20 Nitric acid, pure av.oz. 6 Calcined magnesia sufficient Weigh the nitric acid into a wide, ca- pacious glass flask; weigh half the al- cohol into another vessel; then pour the latter liquid slowly and carefully in a thin stream into the flask so that the alcohol will be superimposed on the acid, during the process disturbing the acid as little as possible. Without agi- tating, set aside for 2 days, then mix, and distil carefully, on a water bath, into a receiver containing the remainder of the alcohol. The condenser and re- ceiver must be thoroughly cooled. Con- tinue distillation until no more vapors arise, in the meantime, however, at any time discontinuing the process should yellow vapors arise. Neutralize the liquid with the magnesia, let stand for 24. hours, and redistil it, beginning with a very low temperature. Discontinue distillation when the distillate weighs 16 av.ounces. — Germ. Pharm. Spirit of Nutmeg. (Essence of Nut- meg — Spiritus Myristicse.) Oil of nutmeg. . . fl.oz. 1 Alcohol fl.oz. 19 — N. F. Appendix and U. S. P. 1890. The preparation of the Brit. Pharm. is 2 times as strong as the above and 5 times as strong as the preparation of the Brit. Pharm. of 1885. Spirit, Ophthalmic. (Alcoholic Eye- Wash.) Oil of lavender flowers m. 10 Oil of rosemary m. 30 Alcohol, to make fl.oz. 1 Mix them by agitation, and, if neces- sary, filter the liquid through paper. Spirit of Orange. Oil of orange peel fl.oz. 1 Deodorized alcohol fl.oz. 19 — U. S. P. 1890. The oil must be perfectly free from terebenthinate odor. 388 STANDARD FORMULARY OF Spirit of Orange, Compound. Oil of orange peel fl.dr. 6 Oil of lemon fl.dr. i l / 2 Oil of coriander m. 40 Oil of anise m. 10 Deodorized alcohol, to make.fl.oz. 4 Keep the product in completely filled, well-stoppered bottles in a cool and dark place.— U. S. P. and N. F. (1st edition). The oil of orange peel used should be that of the bitter orange. This preparation is used in making aromatic elixir. Spirit of Peppermint. (Essence of Peppermint.) I. Oil of peppermint fl.oz. i 1 /* Peppermint herb, bruised or coarsely ground gr. 70 Alcohol, to make fl.oz. 15 Dissolve the oil in 13^2 fluidounces of alcohol, add the herb, macerate for 24 hours, agitating occasionally, filter, and add enough alcohol, through the filter, to make the filtrate measure 15 fluid- ounces. — U. S. P. II. The preparation of the Brit. Pharm. is of the same strength as the above, but is made without the herb, in other words, it is uncolored. This preparation is 5 times the strength of the spirit of peppermint of the Brit. Pharm. of 1885 and half as strong as the essence of peppermint of the same work. III. The preparation of the Germ. Pharm. is made from 1 part by weight of oil and 9 parts of alcohol. IV. A cheap preparation, such as would be suitable for saloon use, may be made as follows : Oil of peppermint fl.oz. 1 Alcohol fl.oz. 24 Water fl.oz. 7 Mix the oil with the alcohol, add the water, color with tincture of curcuma and filter through calcium phosphate or talcum. Spirit of Phosphorus. (Tincture of Phosphorus.) Phosphorus gr. ioj^ Absolute alcohol fl.oz. 16 Weigh the phosphorus in a tared capsule containing water, then dry it carefully and quickly with blotting paper, and introduce it into a flask containing the absolute alcohol. Into the neck of the flask insert a perforated cork stopper bearing a long glass tube about 2 feet long, to serve as an air condenser. Place the flask into a water bath, and heat so that the alcohol may be kept gently boiling, until the phosphorus is dis- solved. Then allow the liquid to cool, and, if necessary, add to it enough ab- solute alcohol to restore the measure to 16 fluid ounces.— U. S. P. 1890. The phosphorus used should be per- fectly translucent and should be cut un- der water. Keep the product in small, dark am- ber-colored, well-stoppered vials, in a cool and dark place. Each fluidram contains about 1/15 gr. of phosphorus. The preparation is intended for mak- ing elixir of phosphorous. It is unsuit- ed for internal administration without corrigents. Care should be taken not to confound it with solution of phosphorus. See also Tincture of Phosphorus for the similar homeopathic preparation. Spirit, Rainworm. (Regenwunn Spiritus or Geist — Spiritus Lum- bricorum.) Ammonium carbonate gr. 25 Dippel's animal oil drop 1 Water fl.oz. 4 Alcohol fl.oz. 12 — H. Spirit of formic acid is also dis- pensed. Spirit of Rosemary. Oil of rosemary fl.dr. 1J/2 Alcohol, to make fl.oz. 15 —Brit. Pharm. This preparation is 5 times the strength of that of the Brit. Pharm. of 1885. Spirit of Sassafras. (Tincture of Oil of Sassafras — Essence of Sassa- fras.) Oil of sassafras. ." fl.oz. 1 Alcohol fl.oz. 11 — Eclectic. PHARMACEUTICAL PREPARATIONS. 389 Spirit of Scurvy-Grass. (Spiritus Cochlearise — Loeffelkraut Spirit- us.) Scurvy-grass, dried av.oz. 3 White mustard, bruised. . . .av.oz. $i Alcohol fl.oz. 29 Water . . :• av.oz. 13 Mix the scurvy-grass, mustard and water, macerate for 3 hours, add the alcohol, and distil off 16 fluidounces. — Germ. Pharm. This spirit may be more conveniently prepared from 60 drops of oil of scurvy- grass, 12 fluidounces of alcohol and 4 of water. The preparation of the former Germ. Pharm. was made by distilling fresh scurvy-grass with water and alcohol. Spirit of Soap. (Spiritus Saponis or Saponatus — Spiritus Saponis Ka- lini — Seifen Geist or Spiritus.) I. Castile soap, in shavings. . .av.oz. 3 Alcohol ..fl.oz. 9V2 Water, to make fl.oz. 16 Introduce the soap into a bottle, add the alcohol and 2^/2 fluidounces of wa : ter, cork the bottle, and immerse in hot water, frequently shaking. When the soap is dissolved, allow the bottle and contents to become cold, add the re- mainder of the water and filter. II. Castile soap av.oz. i^4 Alcohol fl.oz. 12 Water fl.oz. z x A Oil of lavender flowers . .m. 15 — Austr. Pharm. III. Olive oil av.oz. 3 Caustic potassa (90 p. c.) gr. 260 Alcohol fl.oz. 17 Water sufficient Dissolve the potassa in 3 fluidounces of water, mix this with the oil and aVz fluidounces of alcohol in a water bath, and heat to boiling until saponification ensues and a sample of the product makes a clear mixture with water and alcohol. Then add the remainder of the alcohol and the water, allow to cool, and filter. Each of the above should preferably be allowed to stand in a cool place for at least 24 hours before filtering. — Germ. Pharm. The above are similar to Liniment of Soft Soap, or so-called tincture of green soap, which see. Spirit of Soap, Camphorated. (Liquid Opodeldoc.) Spirit of camphor fl.oz. 4 Spirit of soap fl.oz. 11^ Ammonia water fl.dr. 6 Oil of thyme, white fl.dr. y 2 Oil of rosemary fl.dr. 1 Mix and filter. — Germ. Pharm. This may become turbid, so it is best to set it aside in a cool place for several days before filtering. This is similar to Liniment of Soap, which see. Spirit of Spearmint. (Essence of Spearmint.) The U. S. P. spirit is prepared like spirit of peppermint, which see. Spirit of Wintergreen. (Spirit of Gaultheria.) Oil of wintergreen fl.oz. 1 Alcohol .*. fl.oz. 19 — U. S. P. Sponge, Burnt, Artificial. The following mixture may be dis- pensed when burnt sponge is demanded: Potassium bromid gr. 132 Sodium chlorid av.oz. y 2 Potassium iodid av.oz. 1 Ferric oxid av.oz. iY 2 Sodium bicarbonate av.oz. 3 Prepared oyster shell av.oz. 4 Wood charcoal av.oz. g l / 2 Mix and reduce to fine powder. Prepared oyster shell is made by thor- oughly cleaning the shell, then reducing in a mortar, separating the finer par- ticles by elutriation and drying the lat- ter. — H. modified. Sponges, Antiseptic. Sponges for antiseptic purposes should be thoroughly cleansed, bleached, and thoroughly cleansed again by washing freely in water. Then place in a car- bolic solution, or if not desirable to use the latter on account of its odor, which is always suggestive of operations or hospitals, a solution of thymol or other antiseptic may be used instead. 390 STANDARD FORMULARY OF Sponge, Carbolized. Carbolic acid, crystal gr. 375 Alcohol fl.oz. 4 Water, distilled fl.oz. 12^ Bleached sponges are allowed to re- main in this solution for 24 hours, when an equal volume of water is added. The sponges are to remain in the fluid. — D. Sponge Tent. (Compressed Sponge.) Sponge, Mucilage of acacia, Water, each sufficient Mix a sufficient quantity of mucilage of acacia and of water, in the propor- tion of 1 volume of the former to 9 volumes of the latter, and immerse in this liquid, the sponge previously freed from sand and other obvious impurities, and cut into suitable pieces. When the sponge has been thoroughly impregna- ted, firmly wrap twine around it so as to bring it to the desired shape, and then dry it. The sponge thus prepared is best pre- served with the twine wrapped around it. If the twine is removed, special care must be taken to protect the sponge against damp air. Starch, Iodized. (Iodid of Starch.) Starch gr. 475 Iodin gr. 25 Distilled water sufficient Triturate the iodin with a small quan- tity of distilled water, add the starch gradually, and continue triturating until the compound assumes a uniform blue color, approaching to black. Dry it at a temperature not exceeding 40 deg. C, and rub it to a fine powder. Preserve in glass-stoppered vials. — U. S P. 1880. Another method of incorporating the iodin is to dissolve it in ether or chloro- form before adding it to the starch. A so-called "soluble iodid of starch" may be prepared by using white dextrin in place of the starch. Stearate of Morphine. Caustic soda, pure gr. 50 Stearic acid, pure. gr. 355 Morphine hydrochlorid gr. 470 Distilled water sufficient Heat the soda and acid with 10 fluid- ounces of distilled water until dissolved. To the sodium stearate solution ob- tained, add the morphine hydrochlorid previously dissolved in 14 fluidounces of water. Stir the mixture well, collect the precipitate, and wash it on a filter with distilled water until the washings are no longer rendered turbid by hydro- chloric acid, or, after the addition of nitric acid, by silver nitrate. Then dry the precipitate, after which it may be crystallized from alcohol. It contains 50 p. c. of morphine. Stearate of Zinc. Zinc acetate gr. 289 Solut'n of sodium stearate. fl.oz. 64 Distilled water fl.oz. "J2 Dissolve the zinc acetate in 8 fluid- ounces of the water, warm the solution to about 70 deg. C, add the solution of sodium stearate gradually, with con- stant stirring or agitation, add the re- mainder of the water, stir thoroughly, allow to stand a few minutes, transfer to a muslin strainer, wash with water until free from acetate, and finally dry. Instead of the zinc acetate, 379 grains of the sulfate may be used. — Edel's formula. See also the similar preparation of the N. F., Oleo-Stearate of Zinc. Steatins. (Unguenta Extensa.) See Mulls, Plaster and Salve. Storax, Liquid, Purified. (Prepared Storax.) The Brit. Pharm. describes it as being prepared by dissolving in alcohol, filter- ing and subsequently evaporating the solvent. The present Germ. Pharm. gives this process : Heat storax on a water bath until most of the contained moisture is ex- pelled, then dissolve in an equal weight of alcohol, filter, and evaporate the solvent. The 2nd Germ. Pharm. and the pres- ent Austr. Pharm. direct dissolving the storax in half its weight of benzol, fil- tering, and evaporating the solvent. PHARMACEUTICAL PREPARATIONS. 391 Suet, Prepared. (Tallow — Sevum or Sebum— Talg.) Mutton suet is official in the U. S. P. and Brit, and Germ. Pharms., but beef suet is also used. Either may be pre- pared by taking the fat from the vicin- ity of the kidneys of the sheep or cow, cutting into small pieces either by means of a knife or a chopper, heating cau- tiously until the fat is quite melted and then straining with expression through flannel. Dieterich recommends adding to the fatty matter in the dish i/io its weight of dried sodium sulfate in fine powder, continuing the heat for 15 min- utes after thorough fusion has occurred, stirring frequently and filtering by hot filtration. The sodium sulfate removes moisture and assists in separating the membranes. Beef suet has a slightly lower fusing point than mutton suet, otherwise the two are practically alike, so that one or the other may be selected, depending upon the use the product is to serve. Suet, Deer. Beef tallow is usually dispensed for this. It is generally sold either in the form of flat cake or of cylinders about I inch in diameter. It may be. slightly hardened by the addition of about 5 per cent, of spermaceti or white wax. Suet, Salicylated. Salicylic acid gr. 72 Benzoic acid gr. 36 Mutton suet av.oz. 8 Melt the suet on a water bath, add the acid, and dissolve by stirring. — Germ. Pharm. Sulfur, Black. (Sulfur Vivum.) Originally black sulfur is supposed to have been powdered crude sulfur or the residue from the purifications of the sulfur of commerce. Sometimes antim- onous sulfid was found to be present. Kebler, who analyzed a number of sam- ples several years ago, found no uni- formity in their composition, and from the analytical results and other informa- tion gathered at the time he suggested the following formula for making the article factitiously: Sulfur parts 9 Lampblack, or powdered charcoal part 1 If it is necessary to employ antimony sulfid, the following formula gives a fairly good product : Sulfur .' parts 22 Antimony sulfid .parts 3 Black sulfur is used to some extent in domestic veterinary practice as a remedy for scabies and other skin dis- eases. Sulfur Iodid. (Iodid of Sulfur.) Washed sulfur part 1 rbdin parts 4 Mix the two intimately by trituration, introduce the mixture into a glass flask, close the orifice loosely, and by means of a water bath, gradually, and with oc- casional agitation, apply a heat not ex- ceeding 60 deg. C. until the ingredients combine and become of a uniformly dark color throughout. Then increase the heat to the boiling point of the wa- ter, so as to fuse the mass. Should any iodin have sublimed and condensed on the glass, incline the flask so as to com- bine the iodin with the fused mass, and then pour the latter out upon a porce- lain plate or other suitable cold surface. After cooling, break the product into pieces of suitable size, and keep them in a glass-stoppered bottle, in a cool place.— U. S. P. The formula of the Brit. Pharm. dif- fers from the above only in directing sublimed sulfur instead of washed sul- fur. Sulfur, Precipitated. (Lac Sulfur — Milk of Sulfur.) Sulfur, sublimed av.oz. 16 Lime av.oz. 8 Hydrochloric acid, water, each sufficient Slake the lime by the gradual addi- tion of 3 pints of water and then mix it uniformly with 5 pints of water. Add the sulfur, previously sifted, and after thorough mixing add 10 pints of water and boil the mixture during 1 hour, agi- tating or stirring very frequently, and 392 STANDARD FORMULARY OF replacing the water lost by evaporation. Then cover the vessel and permit the contents to cool and to become clear by subsidence. Carefully draw off the clear solution and filter the remainder. To the united liquids add gradually and with constant stirring, the hydrochloric acid, previously diluted with an equal volume of water, until the liquid is nearly neu- tralized, still retaining, however, an al- kaline reaction and a yellow color. Col- lect the precipitate on a strainer, and wash it with water until the washings are tasteless and cease to give a precipi- tate with ammonium oxalate test solu- tion. Then dry the product rapidly, at a moderate heat, and keep it in well- stoppered bottles. — U. S. P. The hydrochloric acid must be of the full U. S. P. strength, viz., 31.9 p. c. ; if weaker, proportionately more of it must be used. The preparation of the market is usu- ally sold under the name lac sulfur and contains calcium sulfate from using sul- furic acid "as the precipitant instead of hydrochloric acid. Sulfur, Washed. (Sulfur Lotum — Sulfur Depuratum.) Sulfur, sublimed av.oz. 16 Ammonia water, 10 p. c....fl.dr. 13 Water sufficient Sift the sulfur through a No. 30 sieve, mix it thoroughly with 16 fluidounces of water, add the ammonia water, and digest for 3 days, agitating occasionally. Then add another 16 fluidounces of wa- ter, shake well, throw the mixture on a muslin strainer, allow the liquid to drain, and wash the sulfur with water until the washings no longer impart a blue color to red litmus paper. Then allow to drain, press the residue strong- ly, dry it rapidly at a moderate heat, and pass it through a Xo. 30 sieve. — U. S. P. Keep the product in well-stoppere J bottles. If the ordinary ammonia water be used, about 3 fluidounces will be neces- sary. The directions of the Germ, and Austr. Pharms. differ from the above only in using 11 fluidounces of water. Suppositories. (Suppositoria.) Suppositories are solid bodies of vari- ous weights and shapes, adapted for in- troduction into the various orifices of the human body, and melting readily at blood heat. They are made with different vehicles, cocoa butter, sodium stearate, glyceri- nated gelatin, agar agar, gum, soap, etc., and are made of different forms, accord- ing to the purpose intended for. The ordi- nary suppositories are the rectal sup- positories (these are understood when- ever the term ''suppositories" is used), nessaries or vaginal suppositories, bou- gies or urethral suppositories, nasal suppositories, and ear suppositories. The latter two kinds are but little em- ployed, while of the other three the rectal suppositories are the ones in most common use. The N. F. does not recognize any sup- positories nor does the Germ. Pharm. The Brit. Pharm. recognizes several co- coa butter suppositories. The U. S. P. recognizes only glycerin suppositories besides giving general directions for making rectal, vaginal and urethral sup- positories of cocoa butter and glycerin- ated gelatin. The N. F. recognizes sup- positories of boroglycerin. Cocoa Butter Suppositories. — The U. S. P. gives the following general process for these: Reduce the medicinal sub- stance, if dry, to very fine powder, or, if an extract, soften it with an appro- priate liquid, then mix it thoroughly in a mortar with about an equal weight of grated cocoa butter and incorporate the remainder of the cocoa butter until a homogeneous, plastic mass is obtained, adding, if necessary, a very small quan- tity of sweet almond oil (castor oil, wool fat or petrolatum are excellent) to assist in making a suitable mass. Roll the mass out on a graduated tile (like a pill tile) into a cylinder, cut this into the required number of equal parts, and PHARMACEUTICAL PREPARATIONS. 393 with a spatula or other suitable mechan- ical aid (or with the fingers), form them into the proper shape. Cocoa butter may be grated by means of an ordinary household grater. In rolling the suppository mass it is customary to use lycopodium as a dust- ing powder to prevent the mass from sticking to the tile and fingers. Suppositories made in the above man- ner are the so-called hand-made supposi- tories and these are preferred by many operators because troublesome heating of the mass and its subsequent cooling and chilling of molds is avoided, also because the medicament is more evenly distributed in the mass. If the process of fusion is preferred for making suppositories, the U. S. P. directs the medicinal substance to be re- duced to a fine powder, or, if an ex- tract, softened with a suitable liquid, then triturated in a mortar with about an equal weight of grated cocoa butter, and having previously melted the re- mainder of the cocoa butter at a gentle heat in a suitable dish provided with a good lip (such as a porcelain capsule or a casserole), add the mixture to the contents of the dish. Allow the whole to cool to about 38 deg. C, and when the mixture begins to show signs of congelation, pour it at once into well- cooled molds of the desired kind. The molds are to be cooled by placing them in a mixture of ice and water for some time before pouring in the suppository mixture into them. Keep the molds at a freezing temperature until the sup- positories have hardened and are ready to be removed. The objection to the fusion process in making cocoa butter is that the medica- ment is not so readily incorporated and will subside to the bottom of the mold (apex of the suppository). This is avoided to a great extent by not pouring the mixture into the molds until it is almost at the point of congelation and keeping it well stirred while pouring into the molds. If the mixture should solidify before pouring from the dish the latter may be very slightly rewarmed. When made in this manner the supposi- tories are also more readily removed from the molds. Before pouring the suppository mix- ture into the molds, the latter should be dusted with lycopodium or be rinsed with soap liniment, liniment of soft soap or spirit of soap to prevent adhe- sion of the suppository to the metal and facilitate its removal. For suppositories containing chloral, phenol, their derivatives, or substances which soften the vehicle, raise the melt- ing point of the cocoa butter by the ad- dition of 10 to 15 per cent, of sperma- ceti, but the melting point must not be raised above 37 deg. C. Unless otherwise specified the U. S. P. directs that rectal suppositories made of cocoa butter should be cone-shaped or spindle-shaped and of the weight of about 30 grains ; urethral suppositories (bougies) should be pencil-shaped, point- ed at one end, either 3 inches long, and weigh about 15 grains, or 6 inches long and weigh about 30 grains ; and vaginal suppositories (pessaries) should be globular or oviform and weigh about 60 grains. The Germ. Pharm. directs that rectal suppositories shall weigh 30 to 45 grains and vaginal suppositories twice as much. Providing the medicating substance is not in powder form, and cannot conve- niently or advantageously be reduced to this form, the method of mixing is not so simple as outlined above. If some- thing like an extract is to be incorpora- ted, this must first be softened with wa- ter, glycerin, diluted alcohol, or alcohol, according to its character, after which it may be mixed with the cocoa butter as before; or it may be that some fixed oil or other substance will be a more suitable softening agent. Possibly the substance is soluble in the cocoa butter in a melted condition; it should, of course, be so dissolved, and after cool- ing and hardening, the mass should be 394 STANDARD FORMULARY OF reduced to powder by grating or other- wise, mixed possibly with a little petro- latum or fixed oil, and be fashioned into suppositories as before. Large quanti- ties of liquids cannot, of course, be in- corporated with cocoa butter masses ; in many instances, however, it will be possible to concentrate the liquid by evaporation without injury to its medic- inal principles ; then, subsequently, the concentrated residue may be mixed with the cocoa butter as before. Cocoa butter suppositories have the advantage of melting at a low tempera- ture and of being readily absorbed, but the disadvantage, when in pencil form, is that they are too brittle. Hence cocoa butter suppositories are generally pre- ferred for rectal and vaginal use, but not for use in the urethra, glycerinated gelatin suppositories being preferred for the latter. Cocoa butter suppositories should al- ways be preserved in a cool place. Elastic cocoa butter urethral supposi- tories may be made as follows (in D.) : Cocoa butter av.oz. 4 Acacia, fine powder av.oz. 2 Glycerin av.oz. 1 Distilled water fl.oz. 1 Melt the cocoa butter at a gentle heat, stir in the acacia, keep at a temperature of 30 to 35 deg. C. for one-half hour, then stir until cool, meanwhile gradu- ally incorporating a mixture of the glyc- erin and water. This mixture is to be preserved in well-closed vessels. When bougies are to be prepared, the medicament is to be mixed with a requisite quantity of the mass, and then rolled out on the pill board or tile. Glycerinated Gelatin Suppositories (usually called gelatin suppositories). — The U. S. P. gives the following general process for making suppositories of glycerinated gelatin (also called glyco- gelatin) : Mix the medicinal substance, if solid and soluble, in water or glycerin, or if a miscible liquid, with a little wa- ter, and add enough glvcerin to make the weight of the mixture one-half that of the finished mass. Then thoroughly incorporate it with an equal weight of melted glycerinated gelatin and pour it at once into suitable molds which have been greased with a small quantity of petrolatum. Cool the molds thoroughly before removing the suppositories. Molds for urethral suppositories should be warmed sufficiently before pouring in the mass to facilitate proper filling of the mold. Suppositories having a firmer consistence may be prepared by substi- tuting mucilage of acacia for a portion of the water or glycerin. If the medic- inal be insoluble in water or glycerin, thoroughly rub it up in a warm mortar with enough glycerin to make the weight of the mixture one-half that of the fin- ished mass. Then thoroughly incor- porate it with an equal weight of melt- ed glycerinated gelatin and pour it into suitable molds as directed above. With bulky powders about one-half the glyc- erin may be replaced with water before levigation (or rubbing in the mortar). Glycerinated gelatin suppositories should be protected against the effects of heat and moisture and dry air by keeping them in tightly closed containers in a cool place. Unless otherwise specified, the U. S. P. directs that urethral suppositories (bougies) of glycerinated gelatin should be pencil-shaped, pointed at one extrem- ity and either 3 inches long and weigh about 30 grains or 6 inches long and weigh about 60 grains ; and vaginal sup- positories (pessaries) should be globu- lar or oviform in shape and weigh about 150 grains. Glycerinated gelatin for suppositories is directed by the U. S. P. to be made as follows : Glycerinated Gelatin. Gelatin av.oz. 8 Glycerin av.oz. 8 Water sufficient Pour upon the gelatin enough water, which has previously been boiled and cooled, to cover it, allow to stand one hour, pour off the water, and allow the PHARMACEUTICAL PREPARATIONS. 395 gelatin to drain for a few minutes, then transfer it to a tared dish, add the glyc- erin, and heat on a water bath until the gelatin is dissolved. Strain the solution while hot and continue the heat on the water bath until the product weighs 16 av.ounces. When cold, cut the mass into pieces, and preserve these in suit- able containers. By suitable containers would be un- derstood well-closed vessels which would prevent undue access of air. Besides the above from the U. S. P. the following from Dieterich's Manual are also used: Hard Glycerin-Gelatin Mass. Gelatin av.oz. 2^ Water fl.oz. 2y 2 Glycerin av.oz. 5 This mass is to be prepared as di- rected, and is then to be evaporated un- til it weighs 10 av.ounces. Soft Glycerin-Gelatin Mass. Gelatin av.oz. V/2 Water_ fl.oz. 4^ Glycerin av.oz. 5 Evaporate this also until it weighs 10 av.ounces. The molds used for bougies are of the hinged kind, so that they may be opened and the bougies taken out; they are constructed of brass, block tin or nickel- plated iron. Before using, the interior of the molds must be rubbed with petro- latum or oil to prevent adhesion of the bougies-; they must also be made quite warm to permit escape of air bubbles. After pouring the mixture into molds, the latter should be placed on ice to cause immediate and rapid hardening of the suppositories. After cooling, the mold should be opened and the bougies taken out and exposed to the air for several hours, that they may harden on the surface after which they should be wrapped in waxed paper and laid hori- zontally in boxes. Or they may be kept in a box, rolled in lycopodium. The boxes should then be well closed. In the absence of a mold, gelatin bou- gies may be formed by means of a glass tube of suitable size. Oil this tube by sucking into it a small quantity of olive oil or liquid petrolatum and allow- ing this to run out again. Now place the tube into the gelatin mass, suck up the latter to the desired height, cover the upper end quickly with the finger, and place the lower end on ice until the lower portion of the mass has solidified ; now remove the finger and lay the tube down on the ice in an inclined position. When the bougie has hardened it may be removed by pushing it out with a smaller glass tube or a rod of some kind. Urethral suppositories or bougies are usually made with gelatin, these being without the brittleness of cocoa butter bougies. Agar Agar Suppositories. — These may be prepared by heating 1 part of pow- dered agar agar with 29 parts of water until dissolved, adding the medicament if soluble or miscible with the vehicle and pouring into conical molds of paper. The latter may be formed from waxed paper with the apex turned over. In some cases the agar is triturated with the medicament, as in the cases of tannin, kneaded with water, and rolled out by hand. Before using agar agar, its slight acid- ity should be neutralized by adding 5 grains of sodium bicarbonate to 1 av.- ounce of powder. Gum Suppositories. — These may be prepared from mixtures of powdered tragacanth, starch, dextrin, sugar and medicament, rubbed to a paste "with water and glycerin, or they may be pre- pared by massing the medicating in- gredient with mucilage of acacia, glyc- erin and water, rolling into the proper form, and then drying. If the supposi- tories contain too large a proportion of medicating ingredient, the latter may be diluted with some inert or harmless body; powdered boric acid will serve acceptably. This kind of a mixture is suitable only for urethral suppositories. Soap Suppositories. — These may be 396 STANDARD FORMULARY OF prepared by incorporating the medica- ment with powdered curd or tallow soap, adding enough glycerite of starch to make a suitable mass, dividing into the requisite number of parts, and rolling these into the suppository form. Sodium Stearate Suppositories. — The U. S. P. recognizes one suppository made with this vehicle, viz., glycerin suppositories, and in this instance the vehicle is derived by chemical combina- tion from stearic acid and sodium car- bonate used in the making of the sup- pository. Suppositories (Urethral), Alum. Alum, powder av.oz. x / 2 Glycerite of starch av.oz. 2V2 Soft glycerin-gelatin mass, .av.oz. 7 Triturate the alum with the glycerite to a smooth paste, add to the melted gelatin mass, heat the whole for a few moments over a naked flame, pour into the hot molds, allow to stand for a few minutes, and then cool rapidly by plac- ing upon ice. The product contains 5 per cent, of alum. — D. These bougies may be made with cocoa butter by triturating the alum with the grated butter, adding oil or petrola- tum to make a suitable mass, rolling out on a pill board or tile, and cutting into suitable lengths. Suppositories of Asafetida. Ethereal fluid extract of asafetida gr. 360 Cocoa butter gr. 390 Heat the extract gently in a capsule on a water bath to expel the ether, add the cocoa butter, melt together, stir for a few minutes, and pour into molds to form 12 rectal suppositories. The orange- colored resin may be rejected as the cocoa butter has dissolved its valuable odorous principle. The resinous deposit may be avoided probably by first melting the cocoa but- ter, then adding the fluid extract, and heating until the ether is driven off. — Eclectic. Suppositories of Atropine. Atropine, alkaloid or sul- fate gr. 1/5 Cocoa butter gr. 390 Make into 12 rectal suppositories. — Eclectic. Suppositories, Belladonna. Extract of belladonna, Brit. Pharm gr. 18 Cocoa butter sufficient The cocoa butter should be enough to form with the extract a mixture which will fill 12 suitable molds of the capac- ity of 15 to 16 grains (or about 1 gram) of the butter. Melt the butter, triturate the extract intimately with a small amount of the butter, add to remainder of the butter, stir well, and as the mixture begins to thicken, pour it into the molds; or let the mixture cool and divide it into 12 equal parts of a conical or other con- venient form for a suppository. — Brit. Pharm. Each suppository contains approxi- mately 1/60 gr. of the alkaloids of bella- donna root. The method usually approved here for making suppositories containing bella- donna or other extract is to make a smooth paste of the extract with water, diluted alcohol, or alcohol (generally di- luted alcohol), triturating this intimate- ly with a small portion of the cocoa but- ter, adding to the remainder of the but- ter in a melted condition, stirring until it begins to thicken, and quickly pouring into well-chilled molds, keeping well stirred meanwhile. Or triturate the paste with all the butter in a grated condi- tion, make a mass by adding a little petrolatum or castor oil, divide into the requisite number of parts, and form the suppositories by hand or with a spatula. Suppositories of Boroglycerin. Glycerinated gelatin gr. 230 Boric acid gr. 60 Glycerin gr. 270 Water gr. 210 Triturate the boric acid with the glyc- erin and water and adc! the mixture to the glycerinated gelatin, melted on a PHARMACEUTICAL PREPARATIONS. 397 water bath. Continue the heat until the boric acid is dissolved, replacing the water if any be lost by exaporation, and pour the mixture into suitable molds, to make 12 rectal suppositories. — N. F. Suppositories, Carbolic Acid. (Phenol Suppositories.) Carbolic acid, crystal gr. 12 White wax gr. 24 Cocoa butter sufficient The cocoa butter should be enough to form, with the acid and wax, a mixture which will fill 12 suitable molds, each of the capacity of 15 to 16 grains (or about one gram) of cocoa butter. Dissolve the acid in butter and wax, previously melted together at a low tem- perature, and pour the mixture into the molds ; or let the mixture cool and then divide into 12 equal parts of a conical or other convenient form for a supposi- tory. Each suppository contains 1 grain of carbolic acid. — Brit. Pharm. Crystal carbolic acid only should be used in making these suppositories as the liquefied form, owing to the presence of foreign liquid, is insoluble in the fatty substances. The wax is added to counteract the softening action of the acid upon the cocoa butter. In the Brit. Pharm. 1885, carbolic acid suppositories (then called carbolic acid suppositories with soap) were directed to be prepared from 12 grains of acid, 180 grains of powdered curd soap, and 40 grains, or a sufficiency, of glycerite of starch. Mix the ingredients so as to form a paste of suitable consistence, divide the mass into 12 equal parts, each of which is to be made into a conical or other convenient form for a suppository. Suppositories (Urethral), Chloral Hydrate. Chloral hydrate gr. 23 Hard glycerin-gelatin mass. av.oz. 1 Reduce the chloral hydrate to fine powder, acid to the melted gelatin mass, stir until dissolved, and pour into warmed bougie molds, and cool by plac- ing on ice. The product contains 5 per cent, of chloral hydrate. — D. Cocoa butter suppositories of chloral hydrate may be prepared by melting to- gether at a gentle heat 26 grains of chloral hydrate, 52 grains of white wax, and 1 av. ounce of cocoa butter, allow to cool until the mass begins to thicken, and pour into well chilled bougie forms. Suppositories, Glycerin. Suppositories containing glycerin may be made either with stearin soap (so- dium stearate) or with gelatin. The former substance will take up or solidify with 'a larger proportion of glycerin. Cocoa butter will take up but a small amount of glycerin. Stearin soap sup- positories of glycerin are preferred in this country and are recognized by the U. S. P. ; gelatin suppositories of glyc- erin are recognized by the Brit. Pharm. I. U. S. P.: Glycerin gr. 450 Sodium carbonate, monohy- drated gr. 8 Stearic acid, pure gr. 30 Water m. 75 To make 10 rectal suppositories. Dis- solve the sodium carbonate in the water and add it to the glycerin contained in a dish on a water bath ; add the stearic acid and heat the mixture carefully until carbonic acid gas ceases to be evolved, and the liquid is clear. Then pour the melted mass into suitable molds, re- move the suppositories when they are completely cold, and preserve them in tightly-stoppered glass vessels. The molds should be perfectly dry and cold. These suppositories are one-half the size of those of the U. S. P. 1890. These suppositories may also be pre- served each in a small vial, or each may be dipped into melted paraffin, using paraffin of low melting point. If these suppositories be protected in some such manner there is no necessity for making them freshly as needed as was directed by the U. S. P. 1800. These suppositories weigh about 50 398 STANDARD FORMULARY OF grains of which about 90 per cent, by weight is glycerin. II. Gelatin, cut small av.oz. 1 Glycerin av.oz. 5 Distilled water sufficient Place the gelatin in a weighed evapor- ating dish with enough distilled water to cover it, let stand for 2 minutes, pour off the excess of water, set aside until the gelatin is quite soft, add the glyc- erin, dissolve on a water bath, evaporate until the mixture weighs 7 av. ounces and 75 grains. Pour the product into suppository molds having capacities equal to 30, 60 or 120 grains of the supposi- tory, or of such other capacities as may be required. — Brit. Pharm. Each suppository contains 70 p. c. of glycerin. III. Wool fat, anhydrous av.oz. 2 Cocoa butter av.oz. i34 White wax ax.oz. 1^ Glycerin av.oz. 2 Distilled water fl.dr. s l A Mix the first three together at a gen- tle heat, incorporate the glycerin and water, previously mixed, and form into 30 suppositories. — H. Suppositories, Iodoform. Iodoform gr. 36 Cocoa butter sufficient Make 12 suppositories. Prepare like belladonna suppositories. — Brit. Pharm. For gelatin suppositories of iodoform, see next article. These suppositories may also he pre- pared by incorporating the iodoform with the cocoa butter in a grated condi- tion, adding a small amount of petrola- tum or castor oil to make a suitable mass, divide into the requisite number of parts, and roll into the form of sup- positories on a pill board or tile. Suppositories (Urethral), Iodoform. I. Prepare like chloral hydrate sup- positories, but using 1 part by weight of iodoform and 3 of either hard or soft glycerin-gelatin mass, but less iodo- form may be used if desired. — D. modi- fied. II. Formula of the Munich Apoth. Verein : Iodoform, fine powder av.oz. 1 Gelatin av.oz. l / 2 Glycerin av.oz. 1 Distilled water fl.dr. 4 Mix the gelatin with the water and glycerin, let stand for 2 hours, then melt the mixture as rapidly as possible on a water bath, add the iodoform previously triturated to a smooth paste with a small amount of water, and pour the warm mixture into forms made of waxed paper. — D. III. Gum suppositories according to the formula of the Munich Apoth. Verein : Iodoform, fine powder av.oz. 1 Acacia, powder gr. 24 Glycerin, distilled water, each sufficient Mix the two powders intimately, and make a suitable mass with a mixture of equal parts by weight of the glycerin and water (or 4 parts by volume of glycerin and 5 of water), roll out into the form of pencils, and dry at 40 to 50 deg. C. If less iodoform is desired in the sup- positories, it may be partially replaced by powdered boric acid. — D. IV. Cocoa butter suppositories may be prepared by mixing intimately 1 part by weight of powdered iodoform with 3 parts of grated cocoa butter, making a mass by the addition of a small amount of petrolatum or castor oil, and rolling out in the form of pencils. Less iodoform may be used if de- sired. Suppositories (Urethral), Iron Chlorid. Solution of ferric chlorid, U. S. P., gr. 168, or m. 130 Glycerite of starch av.oz. Ij4 Soft glycerin-gelatin mass. av.oz. 3^ Melt the glycerite and gelatin mass, add the iron solution, and then proceed as with the alum bougies. — D. PHARMACEUTICAL PREPARATIONS. 399 Suppositories, Lead, Compound. Lead acetate, fine powder gr. 36 Opium, powder gr. 12 Cocoa butter to make 12 suppositories. Prepare like belladonna suppositories. — Brit. Pharm. The suppositories may also be pre- pared by triturating with grated cocoa butter, making into a mass with a small amount of castor oil or petrolatum, di- viding into the requisite number of parts and forming into suppositories on a pill board or tile. Suppositories, Mercurial. Mercurial ointment, 50 p. c. .gr. 60 Cocoa butter gr. 120 Melt the butter with a gentle heat, add the ointment, and, having mixed them thoroughly without applying more heat immediately pour the mixture, before it has congealed, into suitable molds of the capacity of 15 grains; or the liquid mix- ture may be allowed to cool, and then be divided into 12 equal parts, each of which is to be made into a conical or other convenient form for a supposi- tory.— Brit. Pharm. 1885. Suppositories, Morphine. I. Morphine hydrochlorid gr. 3 Cocoa butter to make 12 suppositories. Prepare like belladonna suppositories. — Brit. Pharm. The suppositories may also be pre- pared by triturating the morphine salt with grated cocoa butter, adding a small amount of petrolatum or castor oil to make a suitable mass, dividing into the requisite number of parts, and forming into suppositories on a pill board or tile. II. The Brit. Pharm. 1885 also rec- ognized morphine suppositories with soap which were to be prepared as fol- lows: Morphine hydrochlorid gr. 6 Curd soap, powder gr. 100 Glycerite of starch gr. > 30 Starch, powder sufficient Mix the morphine salt with glycerite and soap, add enough starch to form a mass of suitable consistence, and divide this into 12 equal parts, each of which is to be made into a conical or other con- venient form for a suppository. Less morphine may be used if desired. III. Eclectic : Each suppository is to contain 1/3 gr. of morphine .sulfate and z 2l A gr. of cocoa butter. Suppositories of Potassium Chlorate, Compound. Potassium chlorate, fine powder gr. 180 Alum, fine powder gr. 60 Cocoa butter av.oz. 3 Make into 12 vaginal suppositories. — Eclectic. Suppositories (Urethral), Potassium lodid. Potassium iodid, fine powder.gr. 23 Hard glycerin-gelatin mass. av.oz. 1 Melt the glycerin-gelatin mass on a water bath, add the potassium iodid, when the latter is dissolved, pour the mixture into warmed molds, and cool rapidly by placing on ice. The bougies contain 5 p. c. of potas- sium iodid. — D. Suppositories of Potassium Iodid, Compound. Potassium iodid, powder gr. 96 Extract of conium leaves gr. 36 Cocoa butter gr. 390 Make into 12 rectal suppositories. — Eclectic. Suppositories (Urethral), Silver Nitrate. Silver nitrate gr. 2 Distilled water drops 3 Hard glycerin-gelatin mass. .gr. 400 Dissolve the silver nitrate in the water, add this solution to the glycerin-gelatin mass, previously melted on a water bath, pour into molds which have been warm- ed, and cool rapidly by placing on ice. These bougies contain one-half per cent, of the silver salt. They soon be- come discolored and must be made fresh.— D. Suppositories, Tannic Acid. (Tannin Suppositories.) I. Tannic acid gr. 36 Cocoa butter to make 12 suppositories. Prepare like belladonna suppositories. —Brit. Pharm. 400 STANDARD FORMULARY OF Or the suppositories may be prepared by triturating the acid with grated cocoa butter, adding a small amount of petro- latum or castor oil to make a mass, di- viding into the requisite number of parts, and rolling these into supposi- tories on a pill board or tile. See also Suppositories (Urethral), Tannin. II. The Brit. Pharm. 1885 also recog- nized tannic acid suppositories with soap which were to be prepared as fol- lows: Tannic acid gr. 30 Glycerite of starch gr. 30 Starch powder sufficient Curd soap, powder gr. 100 Make like Suppositories, Morphine No. II, which see. More tannic acid may be used if de- sired. III. Eclectic: Each suppository is to contain 2Y 2 gr. of tannin and 32^2 gr. of cocoa butter. Suppositories (Urethral), Tannin. I. Tannin gr. 47 Alcohol fl.dr. 4 Tragacanth, powder gr. 14 Hard glycerin-gelatin mass. av.oz. 2 Dissolve the tannin in the alcohol, triturate this with the tragacanth, incor- porate with the melted gelatin mass, ex- pose to the heat of a water bath until the alcohol has evaporated, stirring con- stantly meanwhile, pour into molds, which have previously been warmed, and cool rapidly by placing on ice. The product contains 5 per cent of tannin. — D. II. Formula of the Munich Apoth. Verein for gum suppositories of tannin : Tannic acid, Boric acid, powder, each. equal parts Mucilage of acacia, Distilled water, Glycerin, each sufficient Intimately mix the acids, add enough of a mixture composed of equal parts of the three liquids to form a suitable mass, roll into pencils and dry. — D. III. Cocoa butter suppositories may be prepared by triturating the tannin with grated cocoa butter, adding a small amount of petrolatum or castor oil tc make a mass, and rolling into pencils on the pill board or tile. Suppositories of Zinc Sulfate, Com- pound. Zinc sulfate, fine powder gr. 36 Alum, fine powder gr. 120 Cocoa butter av.oz. 3 Make into 12 vaginal suppositories.— Eclectic. Surgical Dressings. For the surgical dressings described' in this work, see the following headings : Bandages, Plaster Paris; Catgut Liga- tures; Cottons; Flannel, Canton; Gauzes; Jutes; Lint; Oakum; Silk Liga- tures ; Silk Protective ; Soap, Surgical ; Sponges, Medicated ; and Wood Wool. Syrup of Acacia. (Syrupus Gummo- sus.) Acacia, selected pieces av.oz. i]/ 2 Sugar av.oz. 12 Distilled water fl.oz. 6 l / 2 Put the acacia into an enameled or porcelain dish, add the water, and stir occasionally until the acacia is dissolved. Add the sugar, place the dish on a water bath, apply a gentle heat, gradu- ally increasing the temperature, and stir- ring from time to time till the sugar is dissolved. Strain the syrup, if neces- sary, and enough distilled water through the strainer to make the product meas- ure 15 fluidounces. This preparation should be made in small quantities, and stored in small, tightly stoppered bottles, in a cool place. — U. S. P. In the U. S. P. 1890, it was made by mixing 1 volume of fresh mucilage of acacia with 3 volumes of simple syrup. Syrup of Albuminate of Iron. See Syrup of Iron Albuminate. Syrup of Almond. (Orgeat Syrup — Syrupus Amygdalarum — Mandel Saft or Syrup.) I. Spirit of bitter almond m. 80 Orange flower water fl.dr. 13 Simple syrup, to make fl.oz. 16 Mix them. PHARMACEUTICAL PREPARATIONS. 401 This preparation is quite different from that of the U. S. P. 1890 which WoS an emulsion of almonds converted into a syrup by the addition of sugar. For those who prefer the old formula it is here given. II. Sweet almond av.oz. 2, gr. 150 Bitter almond gr. 300 Sugar av.oz. zVk Orange flower water fl.dr. 13 Distilled water fl.oz. 2 Simple syrup, to make fl.oz. 16 Blanch all the almonds by immersion in hot water, removing the skins, and drying on a clean cloth. Then rub them in a mortar with V/2 av.ounces of sugar, and Vi fluidounce of distilled water to a smooth paste. Mix this well with the orange flower water and 3^2 fluidounces of simple syrup, and strain with strong expression. To the residue add i l / 2 fluidounces of distilled water, and ex- press again. In the strained liquid dis- solve the remainder of the sugar, with- out heat, adding enough syrup to make the product measure 16 fluidounces. — U. S. P. 1890. Keep the product in well-stoppered, completely filled bottles, in a cool place. Syrup Ammonium Hypophosphite. Ammonium hypophosphite. . .gr. 264 Dil. hypophosphorus acid....m. 15 Distilled water fl.oz. \ l / 2 Glycerin fl.oz. \]/ 2 Comp. spirit vanillin m. 15 Syrup, to make fl.oz. 16 Dissolve the ammonium hypophosphite in the distilled water, add the diluted hypophosphorous acid, filter, and then add the glycerin, compound, spirit of vanillin and sufficient syrup. — N. F. Syrup of Althea. (Syrup of Marsh- mallow — Eibisch Syrup or Saft.) . ..gr. .fl.dr. Althea root, deprived of the bark and cut into small pieces Alcohol , Glycerin fl.oz. Sugar av.oz. Distilled water, to make. . .fl.oz. Wash the drug with cold water, 360 U 16 then macerate it with 6 l / 2 fluidounces of the water previously mixed with alcohol, during 1 hour, stirring frequently, and strain without expressing the residue. In the strained liquid dissolve the sugar" by agitation without heat, add the glycerin, and then enough water to make 16 fluidounces. — N. F. P. 1890. Keep the product in well-stoppered, completely filled bottles, in a cool place. II. Althea root, cut coarse gr. 175 Alcohol m. 1 10 Distilled water fl.oz. g r / 2 Sugar av.oz. 12 Rinse the drug off with water, add the alcohol and water, macerate for 3 hours, agitating occasionally, strain without ex- pression, and in 8 av.ounces of the cola- ture dissolve the sugar by the aid of heat,' filter, and bring the filtrate to the weight of 20 av.ounces, if necessary, by the addition of simple syrup. — Germ. Pharm. Syrup of Apomorphine Rydrochlorid. Apomorphine hydrochlorid. . .gr. 4 Hydrochloric acid, diluted. .. .m. 12 N Alcohol fl.dr. 5^ Distilled water fl.dr. 5^2 Simple syrup, to make fl.oz. 16 Mix the alcohol and water, add the apomorphine salt to it, dissolve by agi- tation, add the acid, and mix with the syrup. — Brit. Form. Syrup of Aralia, Compound. (Com- pound Syrup of Spikenard — Al- terative Syrup.) The following is a practical formula for making this Eclectic syrup : Spikenard root gr. 270 Burdock gr. 270 Yellow dock gr. 270 Guaiac wood . . . .gr. 270 Sassafras bark gr. 180 Prickly ash bark gr. 180 Elder flowers gr. 180 Blue flag root gr. 180 Sugar av.oz. 10 Diluted alcohol sufficient Mix the drugs and reduce to a coarse powder, extract in the usual way by per- colation, with diluted alcohol; obtain 10 fluidounces of percolate in which dis- solve the sugar by percolation and to this solution add, if necessary, enough simple syrup to make 16 fluidounces. 402 STANDARD FORMULARY OF Syrup, Aromatic. Tincture of orange (from fresh bitter peel), Brit. Pharm fl.oz. 4 Cinnamon water fl.oz. 4 Simple syrup fl.oz. 8 Mix the tincture and water, shake the mixture with a little talcum, filter, and add the syrup. — Brit. Pharm. Syrup of Asafetida. Asafetida, select gum av.oz. Yz Boiling water fl.oz. 8 Sugar av.oz. 13 Rub the gum with a portion of the water to a smooth paste, add the re- mainder of the water and sugar, dis- solve by aid of gentle heat and strain. — Eclectic modified. Syrup of Bayberry. The following has been credited to Thomsonian practice : Bayberry bark pounds 2 Diluted alcohol gall, 1 Sugar pounds 2 Macerate the bark with the diluted al- cohol in a warm place for two days, strain, evaporate the colature to 1 quart and in this dissolve the sugar. Syrup of Blackberry Root. (Syrup of Rubus.) Fl'd ext. of blackberry root. fl.oz. 4 Simple syrup fl.oz. 12 — U. S. P. Syrup of Blackberry, Aromatic. (Syrupus Rubi Aromaticus.) Blackberry root . . . .av.oz. 4, gr. 80 Cinnamon gr. 240 Nutmeg gr. 240 Clove gr. 120 Allspice gr. 120 Sugar av.oz. 22 Diluted alcohol, blackberry juice, each, to make fl.oz. 32 'Reduce the blackberry root and the aromatics to a moderately coarse (No. 40) powder, and percolate it, in the usual manner, with the diluted alcohol, until 8 fluidounces of percolate are ob- tained. To this add 14^2 fluidounces of blackberry juice, and dissolve the sugar in the liquid by agitation. Lastly, add enough blackberry juice to make 32 fluidounces. The above really makes more than ^2 fluidounces of product. The blackberry juice should be reduced to 12 fluidounces and the sugar to 20 av. ounces. This is similar to Cordial, Blackberry, which see. Syrup of Black Cohosh, Compound. (Compound of Syrup of Acteea or Cimicifuga.) Fluid ext. of black cohosh. fl. dr. 5 Fluid extract of licorice. . .fl. dr. 2 J / 2 Fluid extract of senega. .. .fl. dr. 2 l / 2 Fluid extract of ipecac m. 75 Wild cherry, moderately fine powder gr. 300 Purified talcum gr. 120 Sugar av.oz. 1 1 Water, to make fl.oz. 16 Mix the wild cherry with 5 fluidounces of water, and allow it to macerate dur- ing one hour. Then add to it the fluid extracts and the talcum, and stir or agitate the mixture frequently and thor- oughly during about 15 minutes. Trans- fer it to a wetted filter, and, when the liquid ceases to drop from the funnel, wash the contents of the filter with water to obtain 8 fluidounces of filtrate. In this dissolve the sugar by agitation, and add enough water, previously passed through the filter, to make 16 fluid- ounces. — N. F. Syrup of Bloodroot. (Syrupus San- guinariae.) Bloodroot, No. 20 powder. av.oz. 3^4 Acetic acid, 36 per cent fl.oz. 2 Sugar av.oz. 13 J/2 Water, to make fl.oz. 16 Mix the acid with 6 fluidounces of water, moisten the bloodroot with a sufficient quantity of this menstruum, and allow it to macerate for 2 hours. Then pack it in a glass percolator, and percolate in the usual manner, first with the remainder of the menstruum previ- ously prepared, and afterwards with water, until 12 fluidounces of percolate are obtained, or until the drug is prac- tically exhausted. Evaporate the perco- late, at a moderate heat, to 7% fluid- ounces. In this dissolve the sugar with a gentle heat, if necessary, and add enough water to make 16 fluidounces. If a somewhat weaker acetic acid be at hand then one of 36 p. c. strengtn, PHARMACEUTICAL PREPARATIONS. 403 proportionately more of it may be em- ployed and correspondingly less water. Each fluidram represents about 13 gr. of bloodroot. — N. F. Syrup of the Bromids. (Syrupus Bromidorum.) I. Potassium bromid gr. 600 Sodium bromid gr. 600 Ammonium bromid gr. 360 Calcium bromid gr. 180 Lithium bromid gr. 60 Comp. tincture of cudbear. fl. dr. 4 Tincture of vanilla fl.oz. 1 Sugar av.oz. 10 Water, to make fl.oz. 16 Dissolve the bromid in 7^2 fluidounces of water, dissolve the sugar in this solu- tion, and the tinctures, and strain. Each fluidram contains about 15 gr. of the combined bromids. — Cine. Acad. Pharm. II. Potassium bromid gr. 600 Sodium bromid gr. 600 Ammonium bromid gr. 360 Calcium bromid gr. 180 Lithium bromid gr. 60 Tincture of vanilla fl.dr. 4 Comp. tincture of cudbear. fl.dr. 2 Comp. syrup sarsaparilla. .fl.oz. 7*4 Simple syrup, to make fl.oz. 16 Dissolve the bromids in the sarsapa- rilla syrup and 5 fluidounces of simple syrup, then add the tinctures and enough simple syrup to make 16 fluidounces. — N. F. Syrup of Buckthorn. (Syrup of Buck- thorn Bark.) This may be prepared as follows: Fluid extract of buckthorn bark fl.oz. 4 Simple syrup fl.oz. 12 This is used principally as a cathartic for dogs. Syrup of Buckthorn Berries. (Syrupus Spinee Cervinse — Syrupus Domes- ticus — Syrupus Rhamni Cathar- ticae.) Sugar av.oz. is l / 2 Fermented juice of buck- thorn berries sufficient Dissolve the sugar in 7^2 fluidounces of the juice, with the aid of a gentle heat, allow the syrup to cool, then add 26 enough of the juice to make 16 fluid- ounces and strain if necessary. This preparation is practically identi- cal with that of the Germ. Pharm. The species of buckthorn to be used is the Rhamnus Cathartica Linne, native of Europe, and naturalized, to some ex- tent, in the United States. If the fresh berries cannot be obtained, the imported fermented juice may be used in prepar- ing this syrup. — N. F. Syrup of Butyl Chloral. See Syrup of Croton Chloral. Syrup of Calcium Hydrochlorophos- phate. (Syrup of Chlorhydro- phosphate of Lime.) Calcium phosphate, precipi- tated gr. 128 Tincture of lemon peel. .. .fl.dr. 2 T A Hydrochloric acid, U. S. P., water, simple syrup, each, to make fl.oz. 16 Triturate the calcium phosphate witr 4 fluidrams of water, and dissolve it with the aid of the acid, avoiding an excess. Then add the tincture, filter the liquid, and wash the filter with a mix- ture of 4 fluidrams each of water and of syrup. Lastly, add enough syrup to the filtrate to make 16 fluidounces. Each fluidram contains 1 gr. of cal- cium phosphate. — N. F. Syrup of Calcium Glycerophosphate. Such . preparation may be made as follow o : Ca.cium glycerophosphate. . . .gr. 64 Citric acid gr. 8 Water fl.oz. 6 Sugar av.oz. 9 Dissolve the calcium salt and acid in the water, then dissolve the sugar with- out the aid of heat, and then add enough simple or flavored syrup or glycerin to make 16 fluidounces. See also Syrup of Glycerophosphate, Compound. Syrup of Calcium Hypophosphite, Syrup of Calcium and Iron Hypo- phosphites. Syrup of Calcium, Manganese and Potassium Hypophosphites. 404 STANDARD FORMULARY OF Syrup of Calcium and Sodium Hy- pophosphite. See Syrups of the Hypophosphites. Syrup of Calcium Iodid. Iodin gr. 560 Iron wire, fine, bright, and finely cut gr. 200 Precipitated calcium carbon- ate gr. 250 Sugar av.oz. 12 Distilled water, simple syrup, each, to make fl.oz. 16 Mix the iron wire with 415 grains of iodin and 3 fluidounces of distilled water, and apply a gentle heat, until the iodin is combined, and the liquid has ac- quired a greenish color. Filter the liquid through a small filter into a flask, con- taining the remainder of the iodin, wash the filter with 1 fluidounce of distilled water, and heat the solution gently, tak- ing care that no iodin is lost by evapora- tion. Heat 4 fluidounces of distilled water in a capacious capsule to boiling, and add to it small alternate portions, first of the calcium carbonate, and then of the solution of iron iodid, in small portions at a time, stirring briskly and waiting until the violence of the reaction moderates before adding a fresh portion. From time to time, add a little distilled water, to replace that lost by evapora- tion. When all the iron solution has been added, continue heating the mix- ture until it is quietly boiling, then filter it through a wetted filter, and ( T ash the latter with enough distilled wa T to make the product, when cold, measure 8 fluidounces. In this dissolve the sugar by agitation, then make up the volume with simple syrup to 16 fluidounces, and strain, if necessary. Each fluidram contains about 5 gr. of calcium iodid. — N. F. A convenient form of iron for the above preparation is the so-called "card teeth." This preparation may also be made by dissolving 640 grains of calcium iodid in 2 fluidounces of water, and adding enough simple syrup to make 16 fluid- ounces. This preparation will not be as satis- factory as the 4) Caustic soda, pure gr. 300 Sugar _ av.oz. 6 X A Distilled water, solution of soda, simple syrup, each... sufficient to make av.oz. 22 Dissolve the caustic soda in 4^2 fluid- ounces of water ; add this solution to the solution of iron chlorid previously mixed with 9 fluidrams of syrup, and set the mixture aside, during 24 hours, in a dark place. Then pour the clear liquid slowly into 34 fluidounces of boiling dis- tilled water, continue the boiling for a few minutes, and then set the mixture aside during one day, in a dark place, so that it may become clear by settling. Withdraw the supernatant liquid by means of a siphon, then wash the resi- due again with 34 fluidounces of boiling distilled water, by decantation. Trans- fer the magma to a wetted strainer, and wash it with hot distilled water, until this runs off colorless, but so that the mass on the strainer still retains a mod- erately strong alkaline reaction. Then allow the excess of liquid to drain off, transfer the moist magma to a tared porcelain capsule, add the sugar, and heat it on a water bath, with exclusion of daylight, during 2 hours, replacing from time to time any water lost by evaporation, and adding, if necessary, solution of soda, drop by drop, until the magma is entirely dissolved. Lastly, add enough simple syrup to make the prod- uct weigh 22 av.ounces, and transfer the product to bottles, which should be com- pletely filled, and stored in a cool and dark place. The caustic soda for this preparation should be pure and contain at least 90 per cent, of absolute soda ; if weaker, proportionately more of it must be used. 100 grains, or about 75 minims, of this syrup represent approximately 1 gr. of metallic iron. The above process is based upon that of the Germ. Pharm. (1st edition). The formula given by the later editions of this work presupposes the keeping in stock of a dry saccharated oxid of iron (see Iron Oxid, Soluble or Saccharated) representing 3 per cent, of metallic iron. When this is available, the syrup may also be prepared by the following form- ula: Saccharated or soluble oxid of iron, Simple syrup, Water, each . . . equal parts by weight Dissolve the oxid in the mixed liquids, PHARMACEUTICAL PREPARATIONS. 421 using a gentle heat if necessary. — N. F. Syrup of Iron (Ferrous) Phosphate. Iron, in wire gr. 63 Phosphoric acid, U. S. P. or 85 per cent . . .fl.dr. 6^ Or 50 p. c. phosphoric acid. fl.dr. 10^2 Simple syrup fl.oz. n J4 Distilled water, to make. .. .fl.oz. 16 Mix the iron with the 85 p. c. acid pre- viously diluted with 10 fluidrams of the water (or the 50 p. c. acid diluted with 6 fluidrams of water) in a small glass flask, close the neck of the latter with cotton, and heat gently until the iron is dissolved. When cold, filter into the syrup and pass the remainder of the water through the filter. Each fluidram contains 1 gr. of an- hydrous ferrous phosphate. — Brit. Pharm. A convenient form of iron to use for the above is what is known as "card teeth." The above preparation may also be made by a process similar to the one given under Syrup of Iron and Ammo- nium Phosphate, the ammonia water and half the acid to be omitted from the latter. Syrup of Iron Phosphate, Compound. See Syrup of the Phosphates, Com- pound. Syrup of Iron Protochlorid. See Syrup of Iron (Ferrous) Chlorid. Syrup of Iron Pyrophosphate. I. Iron pyrophosphate, scale. .. .gr. 64 Distilled water, warm fl.dr. 2 Simple syrup, to make fl.oz. 16 Dissolve the iron salt in the water and add the syrup. An alcoholic solution of some aromatic oil may be added to this mixture. — Eclectic. II. Iron pyrophosphate, soluble, .gr. 90 Distilled water fl.dr. 1 Simple syrup, to make fl.oz. 16 i — Codex. Syrup of Iron and Quinine Iodids. I. Bouchardat's formula : Iodin gr. 42 Iron, powder gr. 17 Simple syrup fl.oz. 15^ Quinine sulfate gr. 8 Diluted sulfuric acid sufficient Distilled water fl.dr. 4 l / 2 Digest the iodin, iron, and 3 fluidrams of the water until the red-brown color of the iodin has disappeared; filter through a small filter into the , syrup. Then dissolve the quinine salt in i 1 /^ fluidrams of water with the aid of dilu- ted sulfuric acid and mix this solution with the previously prepared syrup. II. Quinine sulfate gr. 20 Hypophosphorous acid, 10 per cent sufficient Potassium iodid gr. 8 Simple syrup, to make fl.oz. 8 Syrup of iron iodid (U. S. P.) fl.oz. 8 To the quinine sulfate add about 10 drops of hypophosphorous acid and then a small amount of simple syrup; when the quinine salt is dissolved, add the re- mainder of the syrup and afterwards the potassium iodid dissolved in a few drops of water. Now add the syrup of iron iodid and mix. Should any cloudiness appear, clear it up by a few drops of the hypophosphorous acid. A fluidram of this syrup contains about 4 gr. of dry iron iodid and about 6 gr. of quinine hydriodid. The latter is the best formula, as it is least likely to precipitate. Syrup of Iron, Quinine and Strych- nine Phosphates. See Syrup of Phosphates of Iron. Quinine and Strychnine. Syrup of Iron Superphosphate. Add freshly precipitated iron phos- phate (see manner of preparation under Syrup of Iron and Ammonium Phos- phate) to saturation to a boiling solution of glacial phosphoric acid. On con- centrating and cooling, the product forms a soft mass, which is freely solu- ble in water in all proportions and is free from inky taste. The syrup may be prepared by dis- solving 5 gr. of this substance in a fluidram of simnle syrup. 422 STANDARD FORMULARY OF Syrup of Lactophosphate of Calcium. See Syrup of Calcium Lactophosphate. Syrup of Lactucarium. Tincture of lactucarium fl.dr. 13 Glycerin fl.oz. z l A Citric acid gr. 8 Orange flower water fl.dr. 7 Simple syrup, to make fl.oz. 16 Mix the tincture with the glycerin, also dissolve the acid in the orange flower, mix the two liquids, and filter if necessary. Then add enough simple syrup to make the liquid measure 16 fluidounces. — U. S. P. Syrup of Lactucarium, Opiated. Ext. of French lactucarium. . .gr. 5 Extract of opium gr. 2 l / 2 Citric acid gr. 2 l / 2 Orange flower water fl.dr. 2 Sugar av.oz. 14^2 Distilled water sufficient Pour boiling water, about 10 fluid- ounces, on the lactucarium, add the acid and sugar, dissolve, clarify by adding white of egg and heating to a boil. Strain, add the opium extract, previous- ly dissolved in the orange flower water, and add enough water to make the prod- uct weigh 22 av.ounces (measuring about 16 fluidounces). — Codex. The extract of French lactucarium is prepared as follows : French lactucarium av.oz. I Alcohol, water, each sufficient Reduce the lactucarium to powder, mix with 4^4 fluidounces of alcohol and 17 fluidrams of water, macerate for 10 days, agitating occasionally, and strain with expression. Macerate the residue with a mixture of 12 fluidrams of alco- hol and 6 of water for 3 days, agitating occasionally, and again strain with ex- pression. Mix the two liquids and evap- orate on a water bath to dry extract. Syrup of Lemon. (Syrupus Limonis or Citri.) I. Lemon juice, freshly ex- pressed and strained fl.oz. 8J/2 Lemon peel, fresh av.oz. 2 l / 2 Sugar av.oz. 14 Water, to make fl.oz. 16 Heat the lemon juice to boiling, add the peel, let stand until cold, filter, add enough water through the filter to make the filtrate measure S l A fluidounces, in the latter dissolve the sugar by agitation without heat, and strain.— U. S. P. 1880. The peel should be deprived of the inner white, bitter layer, and should be cut into small pieces. Syrup of citric acid is frequently dis- pensed for syrup of lemon, but the above is a more agreeable preparation. II. Lemon juice fl.oz. 7H Lemon peel, fresh, in thin slices or grated gr. 135 Alcohol sufficient Sugar av.oz. 11^ Macerate the peel in 4 fluidrams of alcohol for 7 days, agitating occasion- ally, press, filter, adding through the fil- ter enough alcohol to make 5 fluidrams. In the lemon juice, clarified by subsi- dence, dissolve the sugar with the aid of a gentle heat. When this is cold, mix it with the alcoholic liquid. — Brit. Pharm. The product should weigh 20 av.- ounces (measuring about 16 fluid- ounces). Syrup of Licorice. (Syrup of Glycr- rhiza — Syrupus Liquiritiee.) I. Pure extract of licorice. . .av.oz. 2%, Glycerin fl.dr. 13 Sugar av.oz. 1 1 Water, to make fl.oz. 16 Dissolve the extract in 8 fluidounces of water, add the sugar, dissolve it by agitation, and strain. Then add the glycerin, and lastly, enough water to make 16 fluidounces. Each fluidram represents about 30 gr. of licorice. — N. F. A better preparation, and one which is more expeditiously obtained, is made by mixing 4 fluidounces of glycerite of licorice with 12 of simple syrup. Either of the above mixtures is un- necessarily strong and much stronger than usually made. A mixture of 2 fluidounces of glycerite of licorice with 14 of simple syrup will suffice for all purposes. PHARMACEUTICAL PREPARATIONS. 423 II. t Licorice root, cut fine av.oz. 4 Ammonia water, 10 p. c fl.oz. 1 Distilled water fl.oz. 15^ Alcohol fl.oz. 2 l A Simple syrup sufficient Mix the root, ammonia and water, let stand for 12 hours, agitating occasional- ly, then express, evaporate the liquid on a water bath to a weight of 2 av.ounces, to this add the alcohol, set aside for 12 hours, filter, and to the filtrate add enough simple syrup to make a total weight of 20 av.ounces. — Germ. Pharm. Syrup of Licorice, Aromatic. (Com- pound Syrup of Licorice.) Hassebrock's formula: Ceylon cinnamon gr. 145 Ginger, Cochin gr. 90 Clove gr. 60 Nutmeg gr. 22 Extract of licorice, purified, .gr. 365 Sugar av.oz. 12^2 Alcohol, water, simple syrup, each, to make. .. .fl.oz. 16 Reduce the first four ingredients to No. 40 powder, extract by the usual process of percolation, using alcohol as a menstruum, until 13 fluidrams of per- colate are obtained, mix this percolate intimately with 6%. av.ounces of sugar, and set the mixture aside in a moder- ately warm place until the alcohol has evaporated. Continue the percolation of the drug with water until 4 fluidounces more of percolate have been obtained, and dissolve the dry, aromatized sugar in this by agitation or percolation. Dis- solve the extract of licorice in 4 fluid- ounces of water, dissolve the remaining 6^4 av.ounces of sugar in this solution by agitation or percolation, mix this syrup with the previously prepared aro- matic syrup, and finally add simple syrup enough to make a total of 16 fluidounces. Syrup of Licorice and Yerba Santa. Fluid extract of yerba santa fl.dr. 6J^ Pure extract of licorice, U. S. P gr. 360 Magnesium carbonate gr. 150 Sugar av.oz. 10 Distilled water, to make, .fl.oz. 16 Mix the fluid extract with the mag- nesium carbonate and lYz av.ounces of sugar in a mortar. Add gradually 3^2 fluidounces of water, filter, and through the filtrate add enough water to make 6 l / 2 fluidounces of filtrate. Add the ex- tract of licorice dissolved in 1 fluid- ounce of water, the remainder of the sugar, heat to boiling, strain and add enough water through the strainer to make 16 fluidounces of colature. — Cine. Acad. Pharm. Instead of the extract of licorice, i l / 2 fluidounces of glycerite may be em- ployed. Keep the syrup n a cool, dark place. This makes a pleasant and perfect vehicle for quinine. ' See also Syrup of Yerba Santa, Aro- matic, Nos. Ill and IV, and Syrup of Yerba Santa and Licorice, Concentrated, and Syrup of Yerba Santa, Licorice and Chocolate, Compound, all of which also contain licorice and yerba santa. Syrup of Lime. (Syrupus Calcis or Calcarias — Saccharated Solution of Lime.) I. Lime (calcium oxid) gr. 480 Sugar av.oz 5^ Water, to make fl.oz. 16 Slake the lime by the addition of 6 fluidrams of water with the aid of heat, then mix it and the sugar thoroughly in a mortar, so as to form a homogeneous powder ; then add the mixture to 8 fluidounces of boiling water, contained in a bright copper or tinned-iron vessel, and boil for 5 minutes, constantly stir- ring. Dilute the liquid with enough water to make it measure 15 fluidounces and filter through white paper, closely covering the funnel during filtration. Then add through the filter enough water to make the product measure 16 fluidounces. Keep the syrup in well-stoppered bottles. The presence of sugar greatly facili- tates the solution of lime in water, so much so that the above may be con- sidered a concentrated lime water, be- 424 STANDARD FORMULARY OF ing about 20 times as strong as the latter. The lime, sugar and water need not be boiled as directed in the official for- mula ; the mixture may be allowed to stand for 2 or 3 days, occasionally agi- tating, then adding water, filtering, etc., as before. II. Brit. Pharm. formula for saccha- rated solution of lime which is the corresponding preparation to the above : Calcium hydrate (slaked lime) gr. 365 Sugar gr. 730 Distilled water fl.oz. 16 Dissolve the sugar in the water and add the lime. Set aside in a stoppered green glass bottle for a few hours, agi- tating occasionally, then siphon off the clear liquid, avoiding unnecessary ex- posure to the air. This contains nearly 2 per cent, of calcium oxid, or about 8 grains to the fluidounce, and is therefore about one- fourth weaker than the first prep- aration, which latter also contains more sugar. Syrup of Liquidambar. Sweet-gum bark, coarsely powdered av.oz. 2^ Sugar av.oz. 13 Water sufficient Moisten the bark thoroughly with water, macerate in a close vessel for 24 hours, pack in a percolator, and pour on water until 8 fluidounces of perco- late are obtained. In this dissolve the sugar by agitation or percolation. — Ec- lectic modified. This has been recommended for the bowel complaints of children, also for chronic cough and mucous affections. Syrup of Lobelia. I. Vinegar of lobelia fl.oz. 8 Sugar av.oz. 14 Dissolve the sugar in the vinegar by the aid of a gentle heat and strain. — Eclectic formula modified. II. This is credited to Thomsonian practice : Lobelia seed or herb pound l / 2 Water gall. 1 Vinegar pint l / 2 Sugar pounds 8 Tincture of lobelia pints 2 Boil the lobelia with the water and vinegar for one-half hour, occasionally replacing the water lost by evaporation, then strain, add the sugar, dissolve, and add the tincture. Syrup of Maidenhair. (Syrup of Adi- antum — Syrupus Capilli Veneris.) I. Infusion of maidenhair. .. .fl.oz. 8 Sugar av.oz. i2 l / 2 Dissolve the sugar in the liquid. The infusion is to be made from an amount of fresh drug equal to 365 grains of dry drug. The fresh drug is preferred. — Eclectic. II. Maidenhair gr. 320 Distilled water, hot fl.oz. 10 Sugar av.oz. 1 1 Macerate the drug in the water for 6 hours, strain, add the sugar, and dis- solve. — Codex. III. Maidenhair, fresh, cut av.oz. 1 Distilled water, hot fl.oz. nj^ Sugar av.oz. 16 Orange flower water m. 45 Heat the maidenhair with the water in a closed vessel on a water bath for an hour, strain, in 10 av.ounces of the colature, dissolve the sugar, strain again, and add the orange flower water. — Austr. Pharm. Syrup of Manganese Hypophosphite. See Syrup of Hypophosphite of Man- ganese. Syrup of Manganese Iodid. Procter's process : Manganese sulfate gr. 960 Potassium iodid gr. 1140 Sugar av.oz. 13 Distilled water, simple syrup, each sufficient Dissolve the two salts each in 3 fluid- ounces of water to which 2 fluidrams of syrup have been added, mix them, place in a cool location for at least on*- PHARMACEUTICAL PREPARATIONS. 425 half hour, filter, allowing the filtrate to pass into a bottle containing the sugar ; add sufficient water through the filter to make the whole measure 16 fluidounces, dissolve the sugar by agitation, and fil- ter if necessary. Each fluidram contains about 7^2 gr. of manganese iodid. Syrup of Manganese and Iron Iodid. See Syrup of Iron and Manganese Iodid. Syrup of Manganese (Saccharated) Oxid. (Syrup of Manganese Sac- charate.) Gerhard's formula: Potassium permanganate ...gr. 255 Sugar av.oz. 85^ Caustic soda, pure....gr. 12 to 15 Distilled water sufficient Dissolve the potassium salt in 28 fluidounces of distilled water, and 3 l / 2 av.ounces of sugar (or 4 l /> fluidounces of simple syrup), and set aside for sev- eral hours to allow a gelatinous precipi- tate to form. Now bring the liquid to the boiling point to make the precipi- tate denser, and separate the latter by filtration. Wash the magna (precipi- tate of manganese hydrate) with a lit- tle distilled water, and press it gently, when the product will be found to weigh somewhat over 4 l / 2 av.ounces. Triturate the latter with 5 av.ounces of sugar and add the soda dissolved in V/2 fluidrams of water, and heat until a clear solution is obtained. Finally add enough distilled water to make ithe product weigh 10 av.ounces (measuring about 8 fluidounces). The product contains 2 per cent, of manganese. Syrup of Manganese Phosphate. Wiegand's formula : Manganese sulfate gr. 940 Sodium phosphate . av.Oz. 3^ or sufficient Hydrochloric acid fl.dr. 5 Sugar av.oz. 13 Water, to make fl.oz. 16 Dissolve the salts separately in 10 fluidounces of water, and add solution of sodium phosphate to the solution of manganese sulfate as long as it pro- duces a precipitate, which wash with cold water, and then dissolve by means of the hydrochloric acid ; dilute this so- lution till it, measure S J A fluidounces, in this dissolve the sugar, adding enough water, if necessary, to make up 16 fluidounces. Syrup of Manna. (Syrupus Mannae or Mannatus.) Manna, best av.oz. 2^4 Sugar av.oz. i^A Alcohol fl.oz. 1 Water, to make fl.oz. 16 Dissolve the manna in 7 fluidounces- of hot water, add the alcohol, set the liquid aside for 12 hours in a moder- ately warm place, and filter. Dissolve the sugar in the filtrate, with the aid of a gentle heat, allow the syrup to cool, and add enough water, passed through the filter previously used, to make 16 fluidounces. — N. F. The product is approximately of the same strength as that which is official in the Germ. Pharm. The latter con- tains only about 4 fluidrams of alcohol and somewhat less sugar, about 11 av.- ounces. Syrup of Mercuric Iodid. (Gibert's Syrup.) Red mercuric iodid gr. 3 Potassium iodid gr. 120 Water fl.dr. 3 Simple syrup, to make. .. .fl.oz. 10 Dissolve the mercuric and potassium iodids in the water and add the syrup. Syrup of Mitchella, Compound. (Com- pound Syrup of Partridge Berry — Mother's Cordial — Compound Syrup of Squaw Vine.) The following is a practical formula for this Eclectic proparation : Mitchella (squaw vine) ... .av.oz. 2 Helonias root av.oz. ^ Cramp bark av.oz. l /> Blue cohosh av.oz. Yz Oil of sassafras drops 4 Sugar av.oz. 9 Water, alcohol, each sufficient Mix the drugs, reduce to powder, add the oil, and percolate in the usual man- ner so as to obtain 11 fluidounces of product, using as a menstruum a mix- 426 STANDARD FORMULARY OF ture of i volume of alcohol and 2 of water ; in this percolate dissolve the sugar. Syrup of Morphine Sulfate. (Syrup of Morphine.) I. Morphine sulfate gr. 4 Water, hot fl.dr. 1 Simple syrup, to make fl.oz. 4 Dissolve the morphine sulfate in the hot water, and add enough simple syrup to make 4 fluidounces. Each fluidram contains Y% gr. of mor- phine sulfate. This preparation is in considerable use in the Southern States. It should, however, never be dispensed in pre- scriptions, unless it is known to be the preparation intended, or unless it is designated as that of the National For- mulary III. V/hen Syrup of Morphine is pre- scribed without any such specific desig- nation or knowledge, it is recommended that the corresponding but weaker prep- aration of the French Pharm. be dis- pensed. The official title of this is Sirop de Chlorhydrate de Morphine (or Sirop de Morphine). This may be prepared approximately of the strength required by the Codex, as in II. II. Morphine hydrochlorid gr. i]4 Water fl.dr. 1 Simple syrup to make fl.oz. 4 Dissolve the morphine hydrochlorid in the water, and add the syrup to make 4 fluidounces. Each fluidram contains about 1/25 gr. of morphine hydrochlorid. — Codex. Syrup of Morphine, Compound. Fluid extract of ipecac m. 15 Fluid extract of rhubarb. . .fl.dr. 2 Fluid extract of senega. .. .fl.dr. 12 Morphine sulfate gr. 4 Oil of sassafras m. 8 (about drops 12) Simple syrup, to make fl.oz.. 16 Dissolve the morphine sulfate in about 1 fluidounce of simple syrup, then add the fluid extracts and the oil, and lastly, enough syrup to make 16 fluid- ounces. Mix the whole thoroughly by shaking. In some sections of the country this preparation is dispensed when Pectoral Syrup or Jackson's Cough Syrup is de- manded or ordered. As the formula differs too much from that originally used by Dr. Jackson it is recommended that the above preparation be dispensed only when it is designated by the title above given. See Syrup, Pectoral, also Syrup, Pec- toral, Compound. Syrup, Mucilaginous. See Thomsonian Remedies. Syrup, Onion. Such a preparation is used some- times ; it has been in great repute among Thomsonians and others and is still largely employed in domestic practice. One method of making it is to slice the onions, slightly brown them, ex- press the juice, and add syrup or honey. Another method is to make a decoction with water, strain, and dissolve sugar in the liquid. Still another method is to arrange sliced onions with alternate layers of sugar and allow to stand in a warm place. Syrup Opiated. (Syrupus Opiatus— Sirop Thebaique.) Extract of opium gr. 20 Water fl.dr. 2 Simple syrup, to make fl.oz. 16 Dissolve the extract in the water and add the syrup. — Codex. Syrup of Orange. (Syrup of Orange Peel.) I. Tinct. of sweet orange peel. fl.dr. 6V1 Citric acid gr. 40 Magnesium carbonate gr. 80 Sugar av.oz. \zV\ Water, to make fl.oz. 16 Triturate the carbonate in a mortar with the tincture, add gradually 6}4 fluidounces of water, filter, and add enough water through the filter to make the filtrate measure 7^2 fluidounces. In this dissolve the acid and sugar by agi- tation without heat, and then add PHARMACEUTICAL PREPARATIONS. 42 r enough water to make the product measure 16 fluidounces. — U. S. P. This syrup should never be made by mixing the fluid extract of orange peel with simple syrup, as is sometimes done. The product is dark, turbid and bitter, in no way resembling a properly-made syrup. II. Tincture of orange, Brit. Pharm volume I Simple syrup volumes 7 —Brit. Pharm. III. Bitter orange peel, cut fine.av.oz. 1 Sherry wine fl.oz. 9 Sugar av.oz. 12 Macerate the orange peel with the wine for 2 days, express, filter; in 8 av.ounces of the filtrate dissolve the sugar. — Germ. Pharm. Syrup of Orange Flowers. Sugar av.oz. 1434 Orange flower water, to make fl.oz. 16 Dissolve the sugar in 7^ fluidounces of the water by agitation, without heat, and add enough of the water to make 16 fluidounces.— U. S. P. The sugar may also be dissolved by percolation as described under Syrup, Simple, which see. The preparation of the Brit. Pharm. is practically the same. Syrup, Pectoral. (Jackson's Pectoral or Cough Syrup.) Morphine hydrochlorid gr. 4 Oil of sassafras m. 4 Syrup of acacia, to make. . .fl.oz. 16 Dissolve the morphine hydrochlorid in about 1 fiuid^unce of the syrup, add the oil of sassafras, and enough syrup to make 16 fluidounces. Each fluidram contains 1/32 gr. of morphine hydrochlorid. The original foimula cf Dr. Samuel Jackson's Cough Syrup was as follow? : Sassafras pith, 60 grains; acacia, 1 ounce ; sugar, 28 av.ounces ; morphine hydrochlorid, 8 grains ; water, enough to make 32 fluidounpes.- The sassafras pith was afterwards uniformly replaced by oil of sassafras, and the other con- stituents of the syrup have been more or less altered, so that a number of different formulas are in vogue in dif- ferent sections of the country. Some- times a small amount of Hoffmann's anodyne is added. It is recommended that the above be followed, if possible, for the sake of uniformity. — N. F. See also Syrup of Morphine, Com- pound; also Syrup, Pectoral, Compound, which latter is also used as Jackson's Syrup. Syrup, Pectoral, Compound. (Jack- son's Cough Syrup.) Fluid extract of ipecac m. 15 Fluid extract of senega m. 90 Fluid extract of rhubarb. ...fl.dr. 2 Morphine sulfate gr. 4 Oil of sassafras. . .drops 18 or m. 8 Simple syrup, to make fl.oz. 16 Dissolve the morphine salt in about 4 fluidrams of syrup, then add the fluid extracts and the oil and enough syrup to make 16 fluidounces. — Cine. Acad. Pharm. This syrup is not to be dispensed when compound syrup of morphine is prescribed, although the latter name has been applied to this preparation. See Syrup of Morphine, Compound; also Syrup, Pectoral. The above formula is an Eclectic modification of Jackson's Syrup. ^ Syrup of Peppermint. Peppermint herb, cut av.oz. 1^2 Alcohol fl.dr. 7 Water fl.oz. 8 Sugar av.oz. 13 Moisten the drug with the alcohol, add the water, let macerate for 24 hours at a temperature of 60 to 70 deg. F., strain, and in 7 av.ounces of the cola- ture dissolve the sugar by agitation. — Germ. Pharm. Syrup of Peru Balsam. (Syrupus Balsamicus.) Peru balsam av.oz. 1 Sugar, water, each sufficient Upon the balsam pour 9^2 fluidounces 428 STANDARD FORMULARY OF of hot water, set aside for 24 hours, occasionally agitating, filter, and in 8 av.ounces of nitrate dissolve 13 av.ounces of sugar.— Germ. Pharm. Syrup of the Phosphates, Compound. (Chemical Food.) I. Precipitated calcium carbon- ate gr. 512 Soluble ferric phosphate (U. S. P.) gr. 256 Ammonium phosphate gr. 256 Potassium bicarbonate gr. 60 Sodium bicarbonate gr. 60 Citric acid av.oz. 2^4 Glycerin fl.oz. 2 Phosphoric acid (85 p. c.).fl.dr. 10^2 Orange flower water fl.oz. 4 Tincture of cudbear fl.dr. 4 Sugar av.oz. 10 Water, to make fl.oz. 32 Triturate the calcium carbonate with the potassium and sodium bicarbonates, the citric acid, glycerin, and orange flower water, and gradually add the phosphoric acid, stirring until solution has been effected. Dissolve the iron and ammonium phosphates in 8 fluid- ounces of hot water, cool, and add the solution to that previously prepared. Filter the whole through a pellet of absorbent cotton placed in the neck of a funnel, and receive the filtrate in a graduated bottle containing the sugar. Agitate until the latter is dissolved, then add the tincture of cudbear, and lastly, enough water to make 32 fluidounces. Each fluidram contains about 2 gr. of calcium phosphate, 1 gr. each of the phosphates of iron and of ammonium, and smaller quantities of potassium and sodium phosphates. — N. F. The above makes a preparation of practically the same strength as Par- rish's. It differs from the latter in con- taining ferric instead of ferrous phos- phate, citric acid instead of hydrochloric acid, being made with bicarbonates in- stead of carbonates, which is an advan- tage, as the former are to be had purer, etc. It is more permanent than Par- ish's preparation, i. e., less liable to precipitate. II. Parrish's original formula : Ferrous sulfate gr. 300 Sodium phosphate gr. 360 Calcium phosphate gr. 360 Glacial phosphoric acid gr. 600 Sodium carbonate gr. 20 Potassium carbonate gr. 30 Cochineal, powder gr. 60 Sugar av.oz. 20 Orange flower water fl.dr. 4 Hydrochloric acid, ammonia water, water, each sufficient Dissolve the iron sulfate in 1 fluid- ounce of boiling water and the sodium phosphate in 2 fluidounces of boiling water. Mix the solutions and wash the precipitated iron phosphate with water until the washings are tasteless. Dissolve the calcium phosphate in 2 fluidounces of boiling water with suffi- cient hydrochloric acid to effect a clear solution ; when cool, precipitate with ammonia water and wash the precipitate with water until the washings are taste- less. To the freshly precipitated phosphates of calcium and iron, as thus prepared, add the phosphoric acid previously dis- solved in water; when clear add the potassium and sodium carbonates, pre- viously dissolved in water, and hydro- chloric acid to dissolve any precipitate which may have formed. Now dilute with water to 11 fluidounces, add the sugar, toward the last add the cochineal, dissolve by heat, strain, cool, and add the orange flower water. This preparation precipitates copious- ly and hence there are many modifica- tions of this formula, such as Nos. I and III. III. Brit. Form, formula for what it calls compound syrup of iron phos- phate : Iron wire, free from rust. . . .gr. 32 Phosphoric acid, 85 p. c... fl.dr. 7J^ Or 50 p. c. phosph. acid... fl.dr. 12^ Calcium carbonate, precipi- tated gr. 100 Potassium bicarbonate gr. 7^2 Sodium phosphate, crystal. . .gr. 7^2 Cochineal, powder gr. 25 Sugar av.oz. n}i Distilled water, to make... fl.oz. 16 Mix the iron with 5 fluidrams of 85 PHARMACEUTICAL PREPARATIONS. 429 p. c. acid and S l A fluidrams of distilled water (or with 8 l A fluidrams of 50 p. c. acid and 2 fluidrams of water) in a glass flask so that the iron is completely cov- ered, plug the neck of the flask with cotton, and heat gently until the iron is dissolved. Dissolve the calcium carbonate in the remainder of the acid mixed with dis- tilled water (the 85 p. c. acid with 14 fluidrams or the 50 p. c. acid with 12 fluidrams), allow to cool, and add the cooled iron solution. Add the potassium bicarbonate and sodium phosphate, dis- solve, and filter the whole. Mix the cochineal with 6 fluidounces of distilled water, boil for 15 minutes, and filter, adding through the filter enough distilled water to make 5^2 fluid- ounces of filtrate. In the latter dissolve the sugar by the aid of heat, strain, allow to cool, add the former filtrate, and finally distilled water enough, if necessary, to make 16 fluidounces. Each fluidram of this syrup contains about y 2 gr. of iron phosphate, about 4/5 gr. of calcium phosphate, with small quantities of potassium and sodium phosphates. The preparation should be kept in filled bottles. Syrup of Phosphates of Iron, Quinine and Strychnine. (Eaton's, Eas- ton's or Aitkin's Syrup — Syrup of Three or Triple Phosphates.) I. Ferric phosphate gr. 155 Quinine gr. 200 Strychnine gr. V/ 2 Phosphoric acid fl.dr. 7 Glycerin fl.dr. 14 Water fl.dr. 7 Syrup, q. s., ad fl.oz. 16 Dissolve the ferric phosphate in the water with the aid of heat, then add the phosphoric acid, the quinine and the strychnine, and stir until dissolved. Fil- ter the liquid into the glycerin contained in a graduated bottle, add sufficient syrup to make the product measure 16 fluid ounces, and mix thoroughly. II. The original U. S. P. formula: Ferrous sulfate, pure .gr. 208 Sodium phosphate, pure, clear crystals gr. 250 Quinine sulfate gr. 133 Strychnine gr. 4 Phosphoric acid, 85 p. c... fl.dr. 12 Or phosphoric acid, 50 p. c. fl.oz. 2. .dr. 5 Sugar av.oz. 10^ Distilled water, diluted sul- furic acid, ammonia water, each sufficient Dissolve the ferrous sulfate in 5 fluid- drams, and the sodium phosphate in 10 fluidrams, of boiling water, mix the so- lutions, collect the precipitate, wash it until the washings are tasteless, and then let drain thoroughly. Dissolve the quinine sulfate in \ l /2 fluidounces of water with the aid of diluted sulfuric acid, precipitate with ammonia water, collect the precipitate, and wash it thoroughly. Dissolve this and the preceding precipitate and the strychnine in the phosphoric acid mixed with enough distilled water to make 9 fluidounces, add the sugar and enough distilled water to make 16 fluidounces, and dissolve by agitation without heat. Instead of precipitating the quinine sulfate, quinine alkaloid may be used in the proportion of 118 grains. The product should measure about 24 fluidounces; to get this, the iron pre- cipitate should be well drained. III. The Brit. Pharm. preparation is called "syrup of phosphate of iron with quinine and strychnine": Iron, in wire gr. 64 Phosphoric acid, 85 p. c... fl.dr. 6 Or 50 p. c. phosphoric acid. fl.dr. io^4 Quinine sulfate gr. 108 Strychnine (alkaloid) gr. 4 Simple syrup fl.oz. 11 J4 Distilled water, to make... fl.oz. 16 Place the iron wire and the acid pre- viously diluted with 10 fluidrams of wa- ter (or the 50 p. c. acid diluted with 6 fluidrams of water), in a small glass flask, close the neck of the latter with cotton, heat gently until the iron is dis- 430 STANDARD FORMULARY OF solved, in the resulting solution dissolve the quinine sulfate and strychnine, filter into the syrup, and pass the remainder of the water through the filter. The iron used may he in the form known as "card teeth.'" Each fluidram of this syrup represents i gr. of anhydrous ferrous phosphate. 4/5 gr. of quinine sulfate, and 1/32 gr. of strychnine. Syrup of Phosphates With Quinine and Strychnine Compound. (Com- pound Syrup of Hydrochloro- phosphates.) See Syrup of Quinine Phospho-Muri- ate, Compound, No. I. Syrup of Phospho-Muriate of Qui- nine, Compound. See Syrup of Quinine Phospho-Muri- ate, Compound. Syrup of Poke, Compound. (Syrupus Phytolaccce Compositus.) The following is a practical formula for this Eclectic preparation : Poke root gr. 580 American ivy bark gr. 580 Black cohosh gr. 290 Sheep laurel .gr. 290 Oil of sassafras drops 3 Oil of wintergreen drops 3 Sugar av.oz. 10 Alcohol, water, each sufficient Mix the drugs, reduce to fine powder, add the oils, and extract by percolation so as to obtain 10 fluidounces of perco- late, using as a menstruum a mixture of 1 volume of alcohol and 2 of water. In this dissolve the sugar, and then add enough simple syrup, if necessary, to make 16 fluidounces. Syrup of Poppy. (Syrupus Papaveris — Syrupus Diacodii.) Poppy capsules av.oz. \ 2 /$ Sugar av.oz. 14 Water, q. s., ad fl.oz. 16 Loosely pack the powder in a suitable metallic percolator and percolate with boiling water until it is practically ex- hausted. Heat to boiling for 2 minutes, concentrate to 15 fluid ounces, dissolve the sugar in the concentrated percolate, add sufficient water, strain, bottle in small bottles and keep in cool place. ^N. F. The tincture of poppy of N. F. Ill was prepared as follows : Poppy capsules, freed from seeds and in coarse pow- der av.oz. S J /i Glycerin fl.oz. 2 Alcohol, water, each, to make fl.oz. 16 Digest the poppy heads with 3 pints of boiling water during 2 hours, then express and strain. Evaporate the cola- ture to 8 fluidounces, mix it with 4 fluidounces of alcohol, and set the mix- ture aside, well covered, until quite cold. Then filter, add the glycerin to the fil- trate, and pass enough of a mixture of 2 volumes of water and 1 of water through the filter to make the product measure 16 fluidounces. II. The above makes a preparation practically like that of the Brit. Pharm. 1885 (not recognized in present edition), which was made as follows: Poppy capsules, freed from seeds, and reduced to No. 20 powder av.oz. 9 Alcohol fl.oz. 4 Sugar av.oz. 16 Distilled water, boiling sufficient Mix the poppy heads with 20 fluid- ounces of water, and infuse for 24 hours, stirring frequently; then pack in a per- colator, add more water, and percolate slowly until about 80 fluidounces of per- colate have been obtained or the drug is exhausted. Evaporate the percolate on a water bath until reduced to 15 fluidounces. When cold, add the alcohol, let the mixture stand for 12 hours, fil- ter, evaporate off the alcohol from the filtrate and evaporate the remainder to 9 l / 2 fluidounces, add the sugar, and dis- solve. The product should weigh 26 av.- ounces (measuring about 19 fluidounces) and have the sp. gr. 1.330. III. The corresponding preparation of the Germ. Pharm. is decidedly weak- er and is prepared as follows : Poppy heads, cut moderate- ly fine av.oz. 2 Alcohol 3 fl-dr. 13 Distilled water fl.oz. 13^ Sugar av.oz. 13 PHARMACEUTICAL PREPARATIONS. 431 Moisten the poppy heads with the alcohol, add the water, macerate for 24 hours, stirring occasionall}-, express, evaporate the liquid to a weight of 7 av.ounces, filter, and in this filtrate dis- solve the sugar. The N. F. suggests that this prepara- tion may be extemporized by mixing 2 fluidounces of the tincture of poppy giv- en under No. I wifh 14 'fluidounces of simple syrup. This is an error; it should be at least 4 fluidounces of tincture with 12 of syrup. Syrup of Quinidine. Quinidine (alkaloid), crys- tals gr. 240 Mucilage of acacia fl.oz. I Solution of saccharin fl.dr. 4 Syrup of orange flowers, to make fl.oz. 16 Mix the quinidine with the mucilage and solution of saccharin, without break- ing up the crystals, and add the syrup of orange flowers. — N. F. This preparation must be well shaken before dispensing it. Syrup of Quinine Phospho-Muriate, Compound. (Compound Syrup of Quinine Phospho-Hydrochlorid — Compound Syrup of Phosphates With Quinine and Strychnine.) I. Potassium bicarbonate gr. 145 Magnesium carbonate gr. 145 Calcium carbonate gr. 145 Soluble ferric phosphate gr. 128 Quinine hydrochlorid gr. 32 Strychnine sulfate gr. 1 Phosphoric acid, 85 p. c... fl.dr. S J A Citric acid gr. 540 Orange flower water fl.oz. 2 Glycerin fl.oz. 4 Sugar av.oz. 8^4 Distilled water, to make. . .fl.oz. 16 Mix the acids with i l / 2 fluidounces of distilled water in a capacious vessel, and gradually add the magnesium and cal- cium carbonates and the potassium bi- carbonate. When effervescence has ceased and all is dissolved, make a solu- tion of the ferric phosphate, the qui- nine hydrochlorid and the strychnine sulfate in the orange flower water by the aid of a little heat, and add this to the first solution, followed by the glyc- erin and sugar. Shake the mixture un- til the sugar is dissolved, add enough distilled water to make 16 fluidounces, and filter.— N. F. II. Potassium bicarbonate gr. 280 Magnesium carbonate gr. 160 Calcium carbonate, precipi- tated gr. 160 Iron phosphate, scale gr. 128 Quinine hydrochlorid gr. 32 Strychnine (alkaloid) gr. 1 Phosphoric acid, U. S. P. or 85 per cent fl.oz. 2 l / 2 Orange flower water fl.oz. 2 Simple syrup, to make fl.oz. 16 Dissolve the salts in a mixture of the phosphoric acid and the orange flower, and add the simple syrup. — Cine. Acad. Pharm. This preparation is to be freshly made when wanted for use. Each fluidram contains ^ gr. of qui- nine muriate, 1/120 gr. of strychnine, 1 gr. of iron phosphate, and about 4 gr. of the combined phosphates of potas- sium, magnesium and calcium. Syrup of Raspberry, (Syrupus Rubi Ideei.) Take any convenient quantity of fresh, ripe raspberries, reduce them to a pulp, and let stand at a temperature of about 20 deg. C, occasionally thoroughly stir- ring, until a small portion of the juice when filtered makes a clear mixture with half its volume of alcohol. Then separate the juice by pressing, and fil- ter it. To every fluidounce of the fil- trate (which should not be allowed to remain unprotected by sugar for more than 2 hours), add ij^ av.ounces of sugar, heat the mixture to boiling, avoid- ing the use of tinned vessels, and strain. — N. F. Keep the product in well-stoppered bottles in a cool and dark place. The above is an acceptable mode of making any of the so-called concentra- ted fruit syrups. The preparation of the Germ. Pharm. differs from the above only in directing a somewhat larger proportion of sugar, 13 av.ounces of sup-ar to 7 av.ounces of juice. 432 STANDARD FORMULARY OF Syrup of Red Clover, Compound. See Syrup of Trifolium, Compound. Syrup of Red Poppy. (Syrupus Rhceados— Klatschrosen Saft.) Red poppy petals av.oz. 4% Alcohol fl.dr. 6 l A Sugar av.oz. 12 Distilled water sufficient Add the petals gradually to 6]/ 2 fluid- ounces of the water kept hot on a water bath, stir frequently, and afterwards, the vessel being removed from the bath, infuse for 12 hours. Then express the liquid, strain, add the sugar, dissolve by heat, and, when the liquid is nearly cold, add the alcohol and enough dis- tilled water to make the product weigh 19^4 av. ounces (measuring about 15 fluidounces).— Brit. Pharm. Syrup of Red Root, Compound. See Syrup of Ceanothus, Compound. Syrup, Restorative. (Restorative Cor- dial.) Thomsonian (in the Guide and the Ma- teria Medica) : Poplar bark oz. 1 Bayberry oz. 1 Boil in 1 pint of water, strain off, add 7 ounces of sugar, dissolve the latter, skim the liquid, and add J / 2 ounce of powdered peach-meats or cherry-stone meats. When cool, add y 2 pint of good brandy. Bitter almonds may be used as a sub- stitute for the peach-meats or cherry- stone meats when the latter are not ob- tainable. Another formula is from Comfort's Practice, as follows: White aspen poplar oz. Vz Black aspen poplar oz. y 2 Bayberry root bark oz. 1 Boil a few minutes in 1 pint of water, strain, add 7 ounces of sugar, dissolve the latter, skim the liquid, and add y 2 ounce of finely powdered peach-meats and 6 fluidounces of brandy. Syrup of Rhatany. (Syrup of Kra- meria.) Fluid extract of krameria. . .fl.oz. 9 Simple syrup fl.oz. 11 — N. F. Syrup of Rhubarb. (Rhabarber Saft.) I. Fluid extract of rhubarb fl.dr. 13 Spirit of cinnamon m. 30 Potassium carbonate gr. 72 Water fl.dr. 6 l / 2 Simple syrup, to make fl.oz. 16 Mix the spirit with the fluid extract, add the potassium carbonate dissolved in the water, and then the syrup. — U. S. P. II. For those who prefer not to make this syrup from the fluid extract, the U. S. P. 1880 formula is appended: Rhubarb root, sliced av.oz. 2 Cinnamon, bruised gr. 180 Potassium carbonate gr. 60 Sugar av.oz. 14 Water sufficient Mix the first three ingredients with 10 fluidounces of water and macerate the mixture in a glass or porcelain ves- sel for 12 hours. Then strain and filter, adding water through the dregs, if neces- sary, to make the filter measure 8 l /> fluid- ounces ; in the latter dissolve the sugar by agitation without heat, and strain, III. Brit. Pharm.: Rhubarb, No. 20 powder, .av.oz. 1 Coriander, No. 20 powder, .av.oz. 1 Sugar av.oz. 12 Alcohol fl.oz. 4 Distilled water fl.oz. 12 Moisten the mixed rhubarb and cori- ander with a portion of the mixed alco- hol and water, set aside for some time, then pack in a percolator and pass the remainder of the liquid slowly through the drug. Evaporate the percolate to 6^4 fluidounces, filter, and dissolve the sugar by the aid of heat. The product should weigh nearly 20 av.ounces (measuring nearly 16 fluid- ounces). IV. Rhubarb, cut av.oz. i Potassium carbonate gr. 45 Borax gr. 45 Cinnamon water, Germ. Pharm fl.oz. 2 Sugar av.oz. 12 J A Water fl.oz. 7^ Mix the rhubarb with the borax, po- PHARMACEUTICAL PREPARATIONS. 433 tassium carbonate and water, and mac- erate for 12 hours, agitating occasion- ally. Then express moderately, bring the colature to a boil, and filter. To 6 J /i av.ounces of filtrate add the cinna- mon water and sugar, and dissolve. — Germ. Pharm. Syrup of Rhubarb, Aromatic. (Spiced Syrup of Rhubarb.) Aromatic tincture of rhu- barb fl.oz. 2^2 Potassium carbonate gr. 8 Simple syrup, to make fl.oz. 16 Dissolve the potassium carbonate in the tincture, filter if necessary, and add the syrup.— U. S. P. Alkaline Mixture of Rhubarb. — Syrup of Rhubarb and Potassium Comp. (Neutralizing Cordial.) Fluid extract of rhubarb. ..fl.dr. 2 Fluid ext. of golden seal. . .fl.dr. I Potassium carbonate gr. 120 Tincture of cinnamon fl.oz. 1 Spirit of peppermint fl.dr. 1 Simple syrup fl.oz. 4 Diluted alcohol, to make., .fl.oz. 16 Dissolve the potassium carbonate in the syrup, and add the solution to the fluid extracts, tincture and spirit, pre- viously mixed with 8 fluidounces of di- luted alcohol. Mix well, add the re- mainder of the diluted alcohol, and filter, if necessary. — N. F. This is only about half the strength of the regular Eclectic preparation in its essential ingredients. Formulas for this preparation vary greatly and so do 'the commercial syrups. The original formula for this Eclectic preparation is the following: II. Original formula of Dr. Beach : Rhubarb, contused av.oz. 2 Peppermint av.oz. 1 Potassium bicarbonate av.oz. 2 Sugar av.oz. 1 Brandy fl.oz. 16 Water, boiling fl.oz. 32 Add the boiling water to the solids, allow to cool, add the brandy, macerate for 3 days, and strain. However, the formula which is usu- ally considered standard by Eclectics is that of Merrell; see No. III. III. MerrelPs formula (accepted Ec- lectic formula) : Rhubarb gr. 580 Potassium bicarbonate gr. 580 Cinnamon gr. 290 Golden seal gr. 290 Oil of peppermint m. 10 Sugar av.oz. 8 Brandy . fl.oz. 22 Water, warm, to make fl.oz. 32 The first four ingredients are to be made into a coarse powder, mixed with the brandy, macerated for 2 days, fre- quently agitated, then expressed with strong pressure; to the liquid add the oil dissolved in a small amount of alco- hol. Extract the marc with enough warm water so that the liquid when added to the previous liquid will make 28 fluidounces. In the latter dissolve the sugar by agitation. The preparation of manufacturers is usually made so as to contain the above proportions of rhubarb, cinnamon and golden seal. Very frequently only one- fourth as much potassium bicarbonate is used, and frequently it is potassium carbonate, which is used in one-fourth amount. The above preparation is equally effi- cacious if made with a mixture of 1 volume of alcohol and 2 of water, in- stead of the brandy and water. The sugar may be increased to 16 av.ounces if a more agreeable preparation is de- sired; in this case the liquid obtained must not exceed 22 fluidounces. Other formulas are also used, among which are the following: IV. Steam's modification: Fluid extract of rhubarb. ..fl.dr. 12 Fluid extract of cinnamon. fl.dr. 4 Fluid extract of hydrastis. . .m. 160 Oil of peppermint m. 4 Potassium carbonate gr. 56 Sugar av.oz. 12 Water, to make fl.oz. 16 Dissolve the potassium carbonate in a small amount of water and mix with the fluid extracts containing the oil of peppermint. Add water to make 5^ fluidounces; filter and wash the filter with water to obtain 8 fluidounces of fil- 434 STANDARD FORMULARY OF trate ; in this dissolve the sugar and add water to make 16 fluidounces. It will be observed that this is much stronger than any of the preceding and should not be used unless specifically demanded. Syrup of Rose. (Syrup of Red Rose.) I. Fluid extract of red rose...fl.oz. 2 Diluted sulfuric acid m. 80 Sugar av.oz. 12Y2 Water, to make fl.oz. 16 Mix the fluid extract and acid with 5 fluidounces of water; allow the mix- ture to stand 2 hours, filter, and dissolve the sugar in the clear filtrate, by agita- tion. Add enough water to the liquid to make it measure 16 fluidounces, and strain if necessary. II. Red rose petals av.oz. 1 Sugar av.oz. 15 Distilled water, boiling fl.oz. gY 2 Infuse the petals in the water for 2 hours, strain and express, heat the cola- ture to the boiling point, filter, and dissolve the sugar in the filtrate by the aid of heat.— Brit. Pharm. The product should weigh 23 av.- ounces (measuring about 18 fluid- ounces). III. This preparation may also be prepared from inspissated extract of rose. See Extract of Rose, Inspissated. Syrup of Rumex, Compound. See Syrup of Yellow Dock, Com- pound. Syrup of Saccharin. Saccharin gr. 150 Sodium carbonate, pure gr. 165 Or sodium bicarbonate, purc.gr. 180 Distilled water fl.oz. 32 Dissolve by the aid of a gentle heat. This may be employed sometimes as a substitute for simple syrup. Syrup of Sarsaparilla. This is usually prepared as follows : Fluid extract of sarsaparilla.. fl.oz. 4 Simple syrup fl.oz. T2 Syrup of Sarsaparilla, Compound. (Syrupus Sarsse Composita.) I. Fluid extract of sarsaparilla.. fl.oz. 13 Fluid extract of licorice r't.. fl.oz. 1 Fluid extract of senna fl.oz. 1 Oil of sassafras drops 8 Oil of anise drops 8 Oil of wintergreen drops 8 Sugar av.oz. 43 Water, to make fl.oz. 64 Add the oils to the mixed fluid ex- tracts, shake the liquid thoroughly, add enough water to make 39 fluidounces, mix well, set aside for 1 hour, and fil- ter. Dissolve the sugar in the filtrate, with the aid of a gentle heat; allow the liquid to cool, strain it, and add enough water through the strainer to make the liquid measure l / 2 gallon. — U. S. P. II. The U. S. P. 1880 formula is ap- pended for those who do not care to use fluid extracts : Sarsaparilla root, No. 30 powder av.oz. 12^2 Guaiac wood, No. 30 powd. av.oz. 1% Pale rose petals, No. 30 pow- der av.oz. 1 Licorice root, No. 30 powd. av.oz. 1 Senna, No. 30 powder av.oz. 1 Sassafras, No. 20 powder. av.oz. Y2 Anise, No. 20 powder av.oz. Y* Wintergreen, No. 20 powd.. av.oz. Y2 Sugar av.oz. 50 Diluted alcohol, water, each sufficient Mix the solid ingredients, except the sugar, with 28 fluidounces of diluted al- cohol and macerate for 48 hours ; then pack firmly in a cylindrical percolator, and gradually pour on diluted alcohol until 48 fluidounces of percolate are ob- tained. Evaporate this on a water bath to 24 fluidounces, add 8 fluidounces of water, filter, and through the filter add enough water to make the filtrate meas- ure 32 fluidounces. In the latter dis- solve the sugar by agitation without heat, and strain. The guaiac and rose may be omitted, as they are not present in the U. S. P. 1890 formula and do not serve any good purpose ; the sassafras, anise and win- tergreen are preferably used in the form PHARMACEUTICAL PREPARATIONS. 435 of volatile oils, which should be added near the latter end of the process. Syrup of Senega. I. Fluid extract of senega part i (by measure) Simple syrup parts 4 (by measure) Mix them.— U. S. P. The U. S. P. syrup of senega is three times the strength of the preparation of the Germ. Pharm., which fact should be borne in mind in compounding pre- scriptions or recipes written in Germany or written by physicians educated in Germany. II. Senega root, cut moderately fine av.oz. 1 Alcohol fl.dr. 9H Water fl.oz. 8M Sugar av.oz. 12 Macerate the drug with the mixed alcohol and water for 2 days, then ex- press the liquid and filter the latter. In 8 av.ounces of filtrate dissolve the sugar. — Germ. Pharm. Syrup of Senna. I. Fluid extract of senna fl.oz. 4 Oil of coriander m. 40 Simple syrup fl.oz. 12 Dissolve the oil in the fluid extract and add the syrup. — U. S. P. The preparations of the Brit, and Germ. Pharms. differ considerably from that of the U. S. P. The former is made by a very complicated process and rep- resents over 8 av.ounces of drug in 16 fluidounces. The preparation of the Germ. Pharm. represents but about 2 av.ounces of drug in 16 fluidounces and is flavored with fennel seed. Syrup of Senna, Aromatic. Fluid extract of senna fl.oz. 2 Jalap ; gr. 360 Rhubarb gr. 128 Cinnamon gr. 30 Clove gr. 30 Nutmeg gr. 15 Oil of lemon. m. 1© Sugar av.oz. ~~ 13 Diluted alcohol, to make. ..fl.oz. 16 28 Reduce the drugs to moderately fine powder, add to it the oil of lemon and percolate it, in the usual manner, with diluted alcohol. Reserve the first 6 fluidounces of percolate, add the fluid extract, and dissolve in this the sugar, with the aid of a gentle heat, if neces- sary, but avoiding loss of alcohol by evaporation. Allow the solution to cool, collect a further portion' of percolate, and add it to the previous' liquid so as to make 16 fluidounces of liquid. — N. F. Each fluidram represents 7J^ gr. of senna, 3 gr. of jalap, and 1 gr. of rhu- barb with aromatics. Syrup of Senna, Compound. Fluid extract of senna (U. S. P.) fl.dr. 17 Fluid extract of rhubarb. . .fl.dr. 4^ Fluid* extract of buckthorn.. fl.dr. 4^ Oil of wintergreen m. 30 Alcohol fl.oz. 1 Simple syrup, to make fl.oz. 16 Dissolve the oil in the alcohol, and add this to the mixed fluid extracts. Then add enough syrup to make 16 fluidounces, and mix by agitation. Each fluidram represents 8 gr. of sen- na, 2 gr.'of rhubarb, and 2 gr. of buck- thorn.— N. F. Syrup of Senna with Manna. (Sy- rupus Mannatus — Compound Sy- rup of Manna.) This preparation of the former Germ. Pharm. may be extemporized as fol- lows: Syrup of senna, U. S. P fl.oz. 2^ Simple syrup fl.oz. 5^2 Syrup of manna, N. F fl.oz. 8 This preparation may be made from the ingredients of the two syrups as follows : Senna, cut gr. 270 Fennel, bruised gr. 30 Manna av.oz. 1 Sugar av.oz. 12 Water sufficient Heat 10 fluidounces of water to boil- ing, add the senna, fennel and manna, macerate for 24 hours, stirring occasion- ally, strain through thick flannel, and filter the colature, adding more warm water to the mass on the strainer so 436 STANDARD FORMULARY OF that the filtrate measures S J A fluidounces. In the latter dissolve the sugar by agi- tation. Syrup, Simple. (Syrup — Syrupus— Syrupus Simplex, Albus or Sac- chari — Weisser Sirup — Weisser Zucker Sirup.) Sugar, dry, crystalline gran- ules (i. e., so-called "gran- ulated") av.oz. 57 Distilled water, to make. .. .gall. Vz Dissolve the sugar, with the aid of heat, in 29 fluidounces of distilled wa- ter, raise the temperature to boiling, strain the liquid, and pass enough dis- tilled water through the (strainer to make the product, when cold, measure 64 fluidounces, and mix the whole thor- oughly.— U. S. P. While these are the directions of the U. S. P., it is probable that they are followed by but few pharmacists. If distilled water is used, the boiling is unnecessary, in fact it is detrimental as it may produce changes in the sugar which will hasten subsequent fermenta- tion of the syrup. Ordinary water may be used as well as distilled water, pro- viding it be a fairly pure potable (drink- ing) water, the total amount of water that is to be used being first brought to a boil, then upon adding the sugar and stirring, the latter will dissolve in a few moments ; allow the syrup to cool somewhat, and strain. The more usual proportions of sugar and water for pre- paring this syrup are 3^2 av.pounds of the former to 2 pints of the latter. The straining cloth should preferably be of some kind of flannel; muslin is not satisfactory. The granulated sugar of the market is as a rule quite pure, but always, or practically always, contains small amounts of ultramarine blue added for the purpose of making the product ap- pear brilliantly white. This blue will pass through the finest straining cloth, will remain suspended in the syrup for a very protracted period of time, and will impart an opalescence to the prod- uct. The only way to obtain an abso- lutely transparent product is by hot fil- tration through filter paper; or the sugar may be replaced by the purer form known as white "rock candy." The U. S. P. gives an alternative process for making simple syrup, as fol- lows : Press down into the neck of a perco- lator of suitable size a pledget of puri- fied cotton, not too tightly, and in such a manner that the cotton shall nearly fill the neck of the percolator, and moist- en it with a few drops of distilled wa- ter. Place the 57 av. ounces of sugar into the apparatus, make its surface level without jarring or shaking, then careful- ly pour on 29 fluidounces of distilled water, and regulate the flow of the liquid, if necessary, so that it will pass out in rapid drops. Return the first portions of the percolate, until it runs through clear, and, when all the liquid has passed, follow it by distilled water, added in portions, so that all the sugar may be dissolved, and the product meas- ure 64 fluidounces. Mix the total per- colate thoroughly. Care must be taken in inserting the pledget of cotton. It must not be too small, as it will then pack into the throat of the percolator and impede percolation. The simple syrup of the Brit. Pharm. is made by dissolving 2 av.pounds of sugar in 15^ fluidounces of boiling dis- tilled water, then adding boiling dis- tilled water to make the product weigh 3 av.pounds. The preparation of the Germ. Pharm. is made from 3 av.pounds sugar and 2 av.pounds of water. Syrup of Sodium Hypophosphite. See Syrup of Hypophosphite of So- dium. Syrup of Spikenard, Compound. See Syrup of Aralia, Compound. Syrup of Squill. (Syrupus Scillse.) Vinegar of squill fl.oz. 7 l /i Sugar av.oz. i^Vi Water, to make fl.oz. 16 Dissolve the sugar in the vinegar with the aid of a gentle heat, then strain, and PHARMACEUTICAL PREPARATIONS. 437 when the strained liquid is cold, add enough water through the strainer to make the liquid measure 16 fluidounces. -U. S. P. The syrup of the Brit. Pharm. is made by dissolving 14J4 av.ounces of sugar in 7J4 fluidounces of vinegar of squill, Brit. Pharm., by the aid of a gentle heat. This preparation may be also made from an acetic fluid extract of squill. Syrup of Squill, Compound. (Hive Syrup.) I. Fluid extract of squill fl.dr. 10^ Fluid extract of senega fl.dr. io>4 Tartar emetic gr. 15 Purified talcum gr. 150 Sugar av.oz. 12^ Water, to make fl..oz. 16 Mix the fluid extracts, evaporate them, in a tared dish, on a water bath, to a weight of 154 av.ounces and mix this residue with $y 2 fluidounces of water. When the mixture is cold, incorporate with it intimately the talcum, filter, pass enough water through the filter to make the filtrate measure 6^ fluidounces, and to this add the tartar emetic dissolved in 3 fluidrams of hot distilled water. Dissolve the sugar in this liouid by agi- tation, without heat, strain, and add enough water through the strainer to make the product measure 16 fluid- ounces. — U. S. P. The sugar may also be dissolved in the liquid by percolation as described under simple syrup. See Syrup, Sim- ple. This preparation contains very nearly I grain of tartar emetic to the fluidram. II. For those who do not care to use the fluid extracts in making this prepara- tion, the U. S. P. 1880 process is ap- pended : Squill, No. 30 powder av.oz. 1%. Senega, No. 30 powder. .. .av.oz. i 1 /^ Tartar emetic .gr. 15 Calcium phosphate, precipi- tated gr. 45 Sugar av.oz. 12 Diluted alcohol, water, each sufficient Mix the squill and senega, moisten with 3 fluidounces of diluted alcohol, and macerate for 1 hour. Transfer to a conical percolator, and gradually pour diluted alcohol upon it until 10 fluid- ounces of percolate are obtained. Boil this for a few minutes, then evap- orate it by means of a water bath to 4 fluidounces ; add 2 fluidounces of boil- ing water, triturate the mixture with the calcium phosphate, filter, and add through the filter enough warm water to make the filtrate measure 8 fluid- ounces. In this dissolve the sugar by agitation without heat, and strain. Last- ly dissolve the tartar emetic in 4 fluid- drams of hot distilled water and mix it with the syrup. Syrup of Starch Iodid. The following is one method of ma- king this preparation: Iodin gr. 30 Starch gr. 250 Ether, water, sugar, each, .sufficient Dissolve the iodin in etfier, pour the solution on the starch and triturate until all the ether has evaporated. Then transfer the mixture to a porcelain cap- sule and heat on a water bath for Y* hour, stirring very frequently. At first considerable iodin vapor is evolved, but this soon ceases. From the soluble starch iodid thus formed, the syrup may be prepared by dissolving 84 gr. in 7H fluidounces of hot water, and in the solution dissolving 14 av.ounces of sugar. This syrup represents 1/1© per cent, of iodin. This preparation may also be made from soluble iodized starch. See Starch, Iodized. Syrup of Stillingia. (Syrup of Queen's Root.) The following is a practical formula for this Eclectic preparation: Stillingia gr. 1160 Prickly ash berries gr. 580 Sugar av.oz. 10 Alcohol, water, each sufficient Reduce the drugs to moderately coarse powder, extract by percolation with a mixture of 1 volume of alcohol and 2 43S STANDARD FORMULARY OF of water so as to obtain 10 fluidounces of percolate; in the latter dissolve the sugar by agitation, strain, and, if neces- sary, add simple syrup to make 16 fluid- ounces of product. Syrup of Stillingia, Compound. I. Comp. fl. ext. of stillingia. .fl.oz. 4 Purified talcum gr. 120 Sugar av.oz. 12 Water, to make fl.oz. 16 Mix the fluid extract with the talcum, and afterwards with 4 l A fluidounces of water, and shake them together thor- oughly. Then pour the mixture upon a wetted filter, add the sugar to the fil- trate, and pass enough water through the filter to make the product, after the sugar has been dissolved by agitation, measure 16 fluidounces. Each fluidram represents 15 m. of compound fluid extract of stillingia (see Extract, Fluid, of Stillingia, Compound). — N. F. The above is an Eclectic preparation, and is of the same strength as the usual Eclectic preparation. In No. II, the drugs themselves are used. II. The following is a practical mod- ification of the original Eclectic formula : Stillingia av.oz. 2 Turkey corn av.oz. 2 Blue flag av.oz. 1 Elder flowers av.oz. 1 Pipsissewa leaves av.oz. 1 Coriander av.oz. Yz Prickly-ash berries av.oz. y 2 Sugar av.oz. 10 Alcohol, water, each sufficient Mix the drugs, reduce to moderately fine powder, and extract by moistening, macerating and percolating in the usual manner, using a menstruum of 1 volume of alcohol and 2 of water, to obtain 10 fluidounces of percolate. In the latter dissolve the sugar by agitation, strain, and add enough simple syrup, if neces- sary, to make 16 fluidounces. Syrup, Strengthening. The following is credited to Thom- sonian practice : Comf rev oz. 4 Elecampane oz. 2 Horehound oz. 1 Beth root, powder oz. y* Brandy pint 1 Sugar pound 1 Water quarts 3 Boil the first three drugs with the water down to 3 pints, and add the re- maining ingredients. Syrup of Styrax or Storax. Storax av.oz. 1 Water, hot fl.oz. 10 Sugar av.oz. 13 Pour water on storax, macerate for an hour, agitatinsr frequently, strain, and in the colature dissolve the sugar. — H. modified. Syrup of Sunflower. Sunflower seed, bruised av.oz. 2 Water fl.oz. 40 Sugar av.oz. 12 Holland gin fl.oz. 12 Boil the seed with the water until but 24 fluidounces of liquid remain, strain, in this dissolve the sugar, and add the gin: — Eclectic. See also Syrup of Helianthus, Com- pound. Syrup of Sunflower, Compound. See Syrup of Helianthus, Compound. Syrup of Sweet Gum. See Syrup of Liquidambar. Syrup of Tamarinds Tamarind pulp av.oz. 4 Sugar av.oz. 5 Water sufficient Digest the pulp with 8 fluidounces of hot water on a water bath for an hour, express gently and strain, in the cola- ture dissolve the sugar by the aid of heat, strain, and add enough water to the product to make it weigh 8 av.- ounces. — H. Syrup of Tar. I. Pine tar gr. 36 Alcohol^ fl.dr. 6H Magnesium carbonate gr. 72 Clean, white sand gr. 75 Sugar av.oz. 14*4 Water, to make fl.oz. 16 Mix the tar intimately, in a mortar, with the sand, add i J / 2 fluidounces of water, and after kneading the mass thor- PHARMACEUTICAL PREPARATIONS. 439 oughly with the pestle, throw the water away. Treat *he residue with alcohol, and, when the tar is dissolved, add the magnesium carbonate and *A av.ounce of sugar, and after thorough trituration add 6 l / 2 fliudounces of water; stir the mixture occasionally during 2 hours, and filter. Dissolve the remainder of the sugar in the clear filtrate by gentle heat, strain, and add enough water to make the liquid measure 16 fluidounces. — U. S. P. II. The preparation of the Brit. Form, is practically like that of the U. S. P. 1890, the tar being rubbed with sand, washed with water, then treated again with water, filtered, and sugar and glycerin added to the filtrate. The process of the present U. S. P. is superior. Syrup of Tolu. (Syrup of Balsam of Tolu — Sometimes Called Syrupus Balsamicus.) I. Tincture of tolu fl.dr. 13 Magnesium carbonate gr. 150 Sugar av.oz. 27^ Water, to make fl.oz. '32 Rub the tincture in a mortar with the magnesium carbonate and 2 av. ounces of sugar, gradually add 15 fluidounces of water, with constant trituration, and filter. Dissolve the remainder of the sugar in the clear filtrate, with the aid of a gentle heat, strain the syrup while hot, and add enough water to the prod- uct to make it measure 32 fluidounces. — U. S. P. The sugar may also be dissolved in the filtered liquid by percolation as de- scribed under simple syrup. See Syrup, Simple. The above process of U. S. P. VIII is practically that of the U. S. P. 1870, an excellent process, and superior to those of the U. S. P. 1880 and 1890. II. Tolu balsam av.oz. x / 2 Sugar , av.oz. 12^4 Distilled water sufficient Boil the balsam with 8 fluidounces of water for half an hour in a lightly cov- ered vessel, stirring frequently. Then remove from the source of heat and add distilled water, if necessary, so that the liquid when cold shall measure 6 I / £ fluid- ounces. Filter the solution, add the sugar, and dissolve by the aid of a water bath. — Brit. Pharm. The product should weigh 19^4 av.- ounces. This is similar to the process of the U. S. P. 1880. Syrup of Trifolium, Comp. (Comp. Syrup of Red Clover.) Fl. ext. red clover blossom..fl.dr. 10 Fluid ext. of burdock root. fl.dr. 5 Fluid extract berberis aqui- folium fl.dr. 5 Fluid ext. cascara amarga. fl.dr. 5 Fluid ext. of poke root. .. .fl.dr. 5 Fluid ext. prickly-ash bark...m. 75 Potassium iodid gr. 144 Sugar av.oz. 11 Distilled water, to make ... fl.oz. 16 Mix the fluid extracts with enough water to make g J / 2 fluidounces, let stand one hour, filter, and percolate the filtrate through the sugar. Dissolve the iodid in the syrup, and add enough water to make 16 fluidounces. — Cine. Acad. Pharm. The above is somewhat stronger than the preparations of the market. The latter contain in 16 fluidounces $>y 2 fluid- drams of red clover blossom, 4% each of the fluid extracts of burdock root, berberis aquifolium, cascara amarga, and poke root, also the same amount of fluid extract of stillingia, 64 minims of fluid extract of prickly-ash bark, and 128 grains of potassium iodid. Syrup, Violet. (Syrupus Violae or Violarum — Veilchen Sirup or Saft.) Fresh petals of violets, care- fully freed from calyces, anthers and stigmas av.oz. 13^2 Sugar av.oz. 14 Distilled water sufficient Heat 24 fluidounces of distilled water in a well-tinned (or porcelain or enam- eled-iron) vessel to about 45 deg. C, add the petals, stir quickly with a glass rod, macerate for 3 minutes, then throw on a carefully cleansed linen strainer, 440 STANDARD FORMULARY OF and express strongly. Transfer the marc, after weighing, to well-tinned ves- sel on a water bath, add boiling hot dis- tilled water to make a total weight of io]/2 av.ounces, and digest for 10 to 12 hours, and express in a well-tinned press (if possible). In 71/4 av.ounces of liquid dissolve 14 av.ounces of sugar on a water bath in a well-tinned vessel. — H. To make a nice syrup, the petals should be freed from calyces, etc., with clean, dry hands, the water must not contain traces of ammonia, and the sugar must be free from alkaline earths. For the latter reason, white rock candy should be preferred to other forms of sugar. If fresh petals are not available, the syrup may be prepared factitiously as follows : Alkanet, bark of root gr. 48 Ipecac root gr. 12 Orris root gr. 72 Sodium carbonate, crystal gr. 72 Alcohol fl.oz. 2 Distilled water, warm fl.oz. 7 Sugar av.oz. 14 Mix the first four ingredients, reduce to coarse powder, add the distilled wa- ter, mix well, then add the alcohol, in- fuse for one hour, express, and in 8 av.ounces of colature dissolve the sugar by the aid of a gentle heat. — H. Syrup of White Pine, Comp. (White Pine Expectorant or Balsam — White Pine Cough Syrup — Sy- rupus Pini Strobi Compositus.) White pine bark av.oz. 3 Wild cherry bark av.oz. 3 Spikenard root gr. 150 Balm of gilead buds gr. 150 Bloodroot gr. 120 Sassafras bark gr. 100 Morphine sulfate gr. 8 Chloroform m. 90 Sugar av.oz. 26 Alcohol, water, simple syrup, each, to make fl.oz. 32 Reduce the vegetable drugs to mod- erately coarse powder, moisten the pow- der with a menstruum composed of 1 volume of alcohol and 7 volumes of wa- ter, and macerate for 12 hours. Then percolate with the same menstruum un- til 16 fluidounces of tincture have been obtained, in which dissolve the sugar and the morphine sulfate; lastly, add the chloroform, and sufficient simple syrup to make 32 fluidounces, and strain. — N. F. White pine bark is the bark of Pinus Strobus. Much of this drug found in the market is valueless, particularly that which is purchased in the ground condi- tion. The ingredients of the N. F. prepara- tion differ somewhat from those of the better class of preparations in the mar- ket. These latter are usually made to contain 960 grains each of white pine and wild cherry, 128 each of spikenard and balm of gilead, 112 of bloodroot, 64 of sassafras, 6 of morphine and 128 minims of chloroform to make 32 fluid- ounces of the preparation. The mor- phine salt used is the acetate, but the sulfate will serve equally well. A cheaper preparation and one which is almost as efficient as the above may be made by using a menstruum of glyc- erin and water as in the following: White pine av.oz. 8 Wild cherry av.oz. 8 Balm of gilead buds av.oz. 1 Spikenard av.oz. 1 Bloodroot av.oz. Y\ Sassafras av.oz. ^ Chloroform fl.oz. ^ Morphine sulfate gr. 24 Sugar av.oz. 64 Glycerin, water, simple syr- up, each, to make gall. 1 Mix the first six drugs, reduce them to moderately fine powder, moisten with a mixture of 1 volume of glycerin and 3 of water, allow to macerate in a closed vessel for 24 hours, pack in a percola- tor, and extract with the same men- struum so as to obtain 80 fluidounces of percolate. In the latter dissolve the morphine and sugar by agitation, strain, and to the colature add the chloroform and enough simple syrup to make I gallon. Sometimes 2 av.ounces of ammonium chlorid is added to the above mixture. Owing to the difficulty of incorpora- PHARMACEUTICAL PREPARATIONS. 441 ting the balm of gilead buds with the other drugs and also owing to its resin- ous character, it is best to bruise this drug alone in a mortar, add 3 fluid- ounces of alcohol, macerating for sev- eral hours, decanting the liquid, adding 2 fluidounces more of alcohol, macera- ting again, and finally straining the liq- uid through a pellet of cotton into the solution of sugar and morphine in the percolate. This may be objected to as it makes a turbid preparation. When the syrun is used for ordinary counter sale, it is best to omit the mor- phine. Syrup of Wild. Cherry. (Syrup of Virginian Prune, Brit. Pharm.) Wild cherry bark, No. 20 powder av.oz. 5 Glycerin fl.oz. 5 Sugar av.oz. 23^2 Water, to make fl.oz. 32 Moisten the drug with a sufficient quantity of water and macerate for 24 hours in a closed vessel; introduce the glycerin into a graduated receiving bot- tle. After the expiration of the 24 hours pack the drug firmly into a cylindrical glass percolator, and gradually pour water upon it until the percolate and glycerin combined measure 15 fluid- ounces (occasionally agitating the liquid during percolation). Dissolve the sugar in the liquid by agitation, without heat, strain, and pass enough water through the strainer to make the product meas- ure 32 fluidounces. — U. S. P. The sugar may also be dissolved in the liquid by percolation as described under simple syrup. See Syrup, Simple. The preparation of the Brit. Pharm. differs from the above only in contain- ing half the amount of gfycerin. In the U. S. P. 1890 the same pro- portions of liquids and drug were used, but the drug was extracted with mixed water and glycerin and the product was therefore of a dark red color and astrin- gent taste. This preparation should never be made by mixing the ordinary commer- cial fluid extract of wild cherry with simple syrup. Syrup of Wild Cherry, Compound. I. This preparation is stated to be used in some portions of the south: Morphine acetate gr. 3 Tincture of bloodroot fl.dr. 2 Wine of antimony fl.dr. 3 Wine of ipecac fl.dr. 3 Syrup of wild cherry fl.oz. 3 Some filter this mixture, others dis- pense it unfiltered. II. This is said to be used in some portions of New England: Fluid extract of wild cherry.fl.oz. 2Y2 Fluid extract of ipecac fl.dr. 4 Fluid extract of bloodroot. .fl.dr. 4 Morphine sulfate gr. 8 Tartar emetic gr. 2 Simple syrup, to make fl.oz. 16 The morphine sulfate and tartar emet- ic should be dissolved in a small amount of hot distilled water before adding to the other ingredients. Syrup of Yellow Dock, Compound. (Compound Syrup of Eumex — Scrofulous Syrup.) This is a satisfactory formula for this Eclectic preparation: Yellow dock av.oz. 2 False bittersweet av.oz. 1 American ivy bark av.oz. ^2 Figwort av.oz. ^2 Sugar av.oz. 10 Alcohol, water, each sufficient Mix the drug, reduce to fine powder and extract by percolation so as to ob- tain 10 fluidounces of product, using a menstruum composed of 1 volume of alcohol to 2 of water; in this percolate dissolve the sugar by agitation or perco- lation, adding enough simple syrup, if necessary, to make 16 fluidounces. Syrup of Yerba Santa. I. Fluid extract of yerba santa. fl.oz 1 Magnesium carbonate av.oz. H Water fl.oz. 7 l A Sugar av.oz. 14 Mix the fluid extract with the calcined magnesia and add the water gradually, with constant stirring; let it stand 24 hours and filter ; add the sugar and dis- solve with the aid of gentle heat. 442 STANDARD FORMULARY OF II. Hellmuth's formula: Yerba santa, No. 40 powd.av.oz. 2 Magnesium oxid gr- 165 Sugar- av^z. 12 Alcohol, water, each sufficient Mix the drug intimately with 55 grains of the oxid, moisten with a mixture of 1 volume of alcohol and 7 of water, let stand for 24 hours, pack tightly in a percolator, and percolate with the same menstruum, taking care that the drug is always covered with menstruum, until 8 fluidounces of percolate are ob- tained. Mix this percolate with the re- mainder of the magnesium oxid, let stand exposed to the air for not less than 48 hours, stirring occasionally, and then run through filter paper until per- fectly clear. Now add the sugar, dis- solve the latter by agitation, and strain the syrup. Syrup of Yerba Stanta, Aromatic. (Aromatic Syrup of Eriodictyon — Comp'd Syrup of Yerba Santa — Syrupus Corrigens.) I. Fluid extract of yerba santa.. fl.dr. 4 Solution of potassa fl.dr. 3 Comp. tinct. cardamom fl.oz. 1 Oil of sassafras m. 4 Oil of lemon m. 4 Oil of clove m. 8 Alcohol fl.dr. 4 Sugar av.oz. 13 Water, to make fl.oz. 16 Mix the fluid extract and solution of potassa, then add 5 fluidounces of water previously mixed with the compound tincture of cardamom, and afterwards add the oils dissolved in the alcohol. Shake the mixture thoroughly, then fil- ter it, and pour enough water through the filter to obtain 8 fluidounces of fil- trate. Pour this upon the sugar con- tained in a bottle, and dissolve it by placing the bottle in hot water, fre- quently agitating. Lastly, cool the prod- uct and add enough water, passed through the filter previously used, to make 16 fluidounces. This preparation is used chiefly for disguising the taste of quinine. For those who desire to use the drugs, the following formulas are appended II. Fenner's formula: Yerba santa Sweet orange peel. Cinnamon Clove Calcined magnesia . . . ..av.oz. 4 ..av.oz. y 2 gr. 60 gr. 60 ..av.oz. Y\ Sugar av.oz. 27 Alcohol, water, each, to make fl.oz. 32 Mix the drugs, reduce to moderately fine powder, incorporate thoroughly with the magnesia, moisten thoroughly with a mixture of 1 volume of alcohol and 7 of water and set aside for 24 hours. Then pack in a percolator, and percolate slowly with the same menstruum to ob- tain 16 fluidounces of percolate. In the latter dissolve the sugar by the aid of a gentle heat or by percolation. The orange peel used should be the fresh peel which has been dried suffi- ciently to admit of grinding. III. Huber's formula : Yerba santa, No. 30 powder.. gr. 240 Licorice root, crushed gr. 240 White oak bark, crushed. .. .gr. 120 Oil of clove drops 4 Oil of lemon drops 2 Oil of sassafras drops 2 Glycerin fl.oz. 1 Sugar av.oz. 12 Water, to make fl.oz. 16 Infuse the three drugs with 8 fluid- ounces of boiling water, allow to stand for 24 hours, agitating occasionally, then filter, adding water through the filter, if necessary, to obtain 7 fluidounces of filtrate. To the latter add the sugar, oils and glycerin, dissolve by agitation, strain, and through the strainer add enough water to make 16 fluidounces. It will be observed that this prepara- tion differs from the others in contain- ing no alkali nor alcohol and in con- taining a tannin-bearing drug (oak bark), which combines with quinine to form a tannate which is insoluble in the saliva and is therefore tasteless. It also contains licorice as does Syrup of Lic- orice and Yerba Santa, and Syrup of Licorice, Aromatic, which see, PHARMACEUTICAL PREPARATIONS. 443 IV. Hellmuth's formula: Syrup of yerba santa, No. II.fl.oz. 14 Aromatic tincture fl.dr. 14 Extract of licorice, powder. . .gr. 70 Mix well and strain. In place of the extract of licorice, glycerite of licorice may be used to ad- vantage, about 3 fluidrams. The aromatic tincture used may be that of the N. R, but the following is to be preferred for the above syrup : Cinnamon av.oz. 1 Dove gr. 60 Cardamom gr. 60 Nutmeg gr. 60 Ginger, Jamaica gr. 60 Diluted alcohol, to make fl.oz. 16 Reduce the drugs to quite fine pow- der, macerate with the diluted alcohol for 7 days, agitating occasionally, and filter clear. V. Mueller's formula: Fluid ext. of yerba santa.. fl.dr. 4 Comp. tinct. of cardamom, .fl.oz. 1 Oil of clove drops 20 Oil of lemon, pure and fresh drops 2 Oil of sassafras drops 10 Alcohol fl.dr. 2 Magnesium carbonate gr. 120 Sugar av.oz. 14 Water, to make fl.oz. 16 Triturate the fluid extract thoroughly with the magnesium carbonate, add the tincture first diluted with 7 fluidounces of water, and then the oils dissolved in the alcohol. Mix the whole thoroughly, allow to stand about an' hour, filter, percolate the filtrate through the sugar, and through the percolator add water enough to make 16 fluidounces. VI. Yerba santa av.oz. 4 Potassium bicarbonate ....av.oz. y 2 Tincture of cudbear fl.dr. 4 Oil of cinnamon drops 16 Oil of clove , drops 8 Oil of anise drops 8 Oil of coriander drops 5 Oil of cardamom drops 5 Alcohol fl.oz. 3 Sugar av.oz. 28 Water, to make fl.oz. 32 Boil the yerba santa and the potas- sium bicarbonate with 3 pints of water for Yz hour, strain, filter, evaporate the filtrate to 12 fluidounces, dissolve the sugar in the filtrate by heat, and add the tincture of cudbear. Dissolve the oils in the alcohol, add 3 fluidounces of water, and filter clear, through talcum, and add to the pre- viously made syrup. Syrup of Yerba Santa and Licorice. See Syrup of Licorice and Yerba Santa. Syrup of Yerba Santa, Ar- omtaic, Nos. Ill and IV; Syrup of Yerba Santa and Licorice, Con- centrated; and Syrup of Yerba Santa, Licorice and Chocolate, Compound, also contain yerba santa and licorice. Syrup of Yerba Santa, Licorice and Chocolate, Compound. Falk's formula : Chocolate (Baker's bitter).. .av.oz. 2. .gr. 90 Extract of licorice, purified. . av.oz. 2. .gr. go Fluid extract of yerba santa. fl.oz. 1 Honey fl.oz. 5 Potassium carbonate . gr. 60 Saccharin '. gr. 16 Oil of sassafras drops 6 Oil of anise drops 6 Oil of cinnamon drops 10 Oil of wintergreen drops 15 Water, to make fl.oz. 16 Shave the chocolate to thin slices into a mortar, add 2 fluidounces of water, place the mortar in a moderately warm place for 1 or 2 hours, stirring occa- sionally so as to form a smooth paste, and then add the extract of licorice and honey, mixing thoroughly. Dissolve the potassium carbonate in 1 fluidounce of water and in this dissolve the saccharin. Add this solution to the previously pre- pared mixture, and when the slight ef- fervescence has ceased, add the fluid ex- tract slowly and with constant tritura- tion. Then incorporate the essential oils and enough water to make 16 fluid- ounces. This combines the three best known disguisers of quinine, viz., yerba santa, licorice and chocolate, which are aided by the clinging sweetness of saccharin. The potassium carbonate serves the double purpose of permitting the mixing 444 STANDARD FORMULARY OF of the resinous fluid extract of yerba santa with an aqueous medium, and by rendering the mixture slightly alkaline prevents the solution, to a certain ex- tent, of suspended quinine sulfate. This latter compound may be dis- guised by this syrup in the proportion of 4 grains of salt to a teaspoonful of syrup. Syrup of Yerba Santa and Licorice, Concentrated. Hassebrock's formula: Fluid ext. of yerba santa .. fl.oz. I Oil of lemon, pure and fresh drops 3 Oil of sassafras drops 3 Oil of clove drops 6 Oil of cassia drops 6 Oil of wintergreen drops 6 Glycyrrhizin gr. 120 Water, warm fl.dr. 6 Honey, to make fl.oz. 6 Evaporate the fluid extract on a water bath to half its volume, while still warm, add 1 fluidounce of honey, and mix well. Dissolve the glycyrrhizin in the water and mix thoroughly with 2 fluid- ounces of honey. Rub the oils with 1 fluidounce of honey, add this to the other mixture, and finally add honey enough to make 6 fluidounces. This is a concentrated preparation of yerba santa and licorice, 1 fluidounce of which is capable of disguising the taste of 10 grains of quinine sulfate. Syrup of Zinc Iodid. Zinc, granulated gr. 250 Iodin gr. 820 Sugar av.oz. 13^2 Distilled water, to make, .av.oz. 22^4 Digest the zinc in a bottle or flask with the iodin and 4 fluidounces of wa- ter, agitating occasionally, until the color of iodin has disappeared. Filter into a bottle containing the sugar, rinse the vessel with 2 fluidounces of water, and pass the rinsings through the filter with sufficient additional water to make the total weigh 22^ av. ounces ; finally agi- tate until the sugar is dissolved, and strain if necessary — Eclectic. The product contains about 10 per cent, of zinc iodid. Tablets, Antiseptic. These usually contain mercuric chlo- rid with some other constituents, such as citric acid or sodium chlorid. They occur in two sizes, a large and a small. The large form usually appears on the market with either citric acid or sodium or ammonium chlorid. Those with citric acid contain 3 4/5 gr. of acid and 73/10 gr. of mercuric chlorid. Those with sodium chlorid contain 7 7/10 gr. of the latter with 7 3/10 gr. of mercuric chlorid. The third kind, called Dr. C. M. Wilson's, contain 7 7/10 gr. of mercuric chlorid and 73/10 gr. of ammonium chlorid. If one of the above tablets be added to one pint of water, the product will be a solution of 1 of mercuric chlorid in 1000 parts of liquid. The small tablets, called Bernay's, contain 1 41/50 gr. of mercuric chlorid and 87/100 gr. of citric acid. One tablet in a pint of water makes a solution of 1 part of antiseptic in 4000 parts of liquid. There are other- "antiseptic tablets" besides those enumerated above. Sei- ler's alkaline antiseptic tablets contain the ingredients of Seiler's antiseptic so- lution. See Solution, Antiseptic, Sei- ler's. Yarrow's antiseptic tablets contain the following ingredients : Sodium borate gr. 3 Boric acid gr. 3 Zinc sulfocarbolate gr. 3 Alum gr. 3 Oil of spearmint m. 1/10 Carbolic acid gr. 1/20 Oil of wintergreen m. 1/20 Eucalyptol gr. 1/2 Thymol gr. 1/8 Tablets of Nitroglycerin. (Trinitrin Tablets.) Tablets of chocolate each weighing 5 grains and containing i/ioo grain of the trinitroglycerin of commerce. — Brit. Pharm. Dose, 1 to 2 tablets, PHARMACEUTICAL PREPARATIONS 445 Tablets, Plasma Nasal. Each tablet is to contain Sodium chlorid gr. 51/2 Sodium sulfate gr. 1 1/2 Sodium phosphate gr. 1/4 Potassium chlorid gr. 2/5 Potassium sulfate gr. 1/4 Potassium phosphate gr. 1/3 Menthol gr. 1/15 This tablet was suggested by Dr. Mur- ray McFarlane, and is a decided im- provement over any other combination offered for the same purpose. One tab- let dissolved in about 2 fluidounces of warm water yields a solution that close- ly resembles the blood serum in compo- sition and specific gravity. The use of this solution, which does not favor un- equal osmosis, will not cause pain or other disagreeable effects. The menthol in small amount is also beneficial on ac- count of its soothing effect. Tablets of (Atificial) Vichy Salt with Lithium, Effervescing. Artificial Vichy salt, N. F. . .. av.oz. 7. .gr. 370 Lithium citrate . .. .av.oz. 9. .gr. 65 Saccharated sodium bicar- bonate av.oz. 9. .gr. 275 Saccharated tartaric acid. . . . ;•••■ -av.oz. 4. .gr. 350 Saccharated citric acid av.oz. 4. .gr. 350 Granulate according to general form- ula under Salts, Effervescent, then di- vide into 1000 compressed tablets. Each tablet contains 3 gr. of artificial Vichy salt and 4 gr. of lithium citrate. — Cine. Acad. Pharm. Talc, Purified. Talc, fine powder av.oz. 25 Hydrochloric acid, U. S. P. .fl.dr. 21 Water -. sufficient Mix the powdered talc with about 100 fluidounces of boiling water, gradually add 14 fluidrams of the acid and boil the mixture during 15 minutes, then al- low it to stand for 15 minutes. Decant and reject the supernatant liquid con- taining the finer particles of talc in sus- pension, and again boil the residue with 100 fluidounces of water mixed with 7 fluidrams of the acid and allow it to stand for 15 minutes, Again decant, and reject the finer suspended particles and wash the coarser residue with wa- ter by repeated decantation until a por- tion of the wash-water, after filtering and acidifying with nitric acid, fails to become opalescent upon the addition of silver nitrate solution. Then transfer the magma to a close linen or muslin strainer, allow it to drain, and dry it at 110 deg. C. A purified, native, hydrous, magnesium silicate sometimes containing a small amount of aluminum silicate. — U. S. P. The U. S. P. IX gives no process for the purification of talc. See Suets. Tartar, Soluble. (Soluble Cream of Tartar — Tartarus Boraxatus — Kali Tartaricum Boraxatum — Boro-Tartrate of Potassium.) Sodium borate av.oz. 2 Potassium bitartrate, pure, powder ..av.oz. 5 Distilled water fl.oz. 15 Dissolve the borax in the water in a porcelain vessel by the aid of heat, then add cream of tartar, stir till dissolved, keeping the vessel meanwhile on a wa- ter bath, filter, evaporate the liquid at a gentle heat to thick consistency, allow to cool, break the tough mass into small pieces, dry these completely by placing in a moderately warm place, then pow- der, and transfer to well-stoppered bot- tles. — Germ. Pharm. Teas. See Species. Thomsonian Remedies and Prepara- tions. Samuel Thomson was an "illiterate farmer," as he described himself, who was born in the eastern United States in 1769. After he had grown to man- hood, he acquired some knowledge of the native herbs of his section of the country, of their medical properties and of medicine. From this time until his death he practiced medicine, but with the virulent opposition of the regular medical fraternity. No doubt many of his ideas relating to diseases and their 446 STANDARD FORMULARY OF cure were fallacious, but so were the ideas of the regular profession, as has since been amply proved. Thomson gained headway in spite of all opposi- tion and many of his preparations are still in use. Two of them, No. 6 and Composition Powder, are recognized by the N. F. A course of treatment by Thomson meant vomiting, sweating, etc. His great axiom was that ''heat is life, and cold is death." He vomited his patients with lobelia, the internal heat was produced with capsicum and other "hot" sub- stances, the sweating was produced by hot drinks of various kinds, assisted by wrapping in blankets. Among the fa- vorite remedies of Thomson were lo- belia, capsicum, bayberry, skunk cab- bage, ladies' slipper root, balmony, pop- lar bark, etc. Thomson had several of his prepara- tions patented, patents being issued in 1813, 1823 and 1836. He also wrote sev- eral medical works which were of un- usual excellence, considering their source and the time at which they were writ- ten. Thomson traveled about in the vari- ous portions of the then limited popu- lated area of the United States, grant- ing "patents" to practice his system of medicine to those who bought his book, price about $25.00. The preparations of Thomson were numbered by him from 1 to 6, but there were also a number of other prepara- tions used by him. The formulas given in this work are copied from his "New Guide to Health" (edition 1827), "Thomsonian Materia Medica," by Sam- uel and John Thomson, the latter a son of Samuel (edition of 1840), "Thom- sonian Practice of Medicine," by Reuben Chambers, and some other works, and also include some other formulas which are current as formulas for Thomsonian preparations. The formulas from the first-named are marked "From the Guide," from the second "From the Ma- teria Medica," and from the third "From Chambers' Practice." These formulas are copied as they appear in the original text ; it will be observed that many are ambiguous. Others of Thomson's followers also wrote works, some of them apparently with his sanction, or, at least, cogni- zance, and these mention preparations other than those used by Thomson, but which are now classed as Thomsonian preparations. Thomson did not apparently have any regular or "set" formulas for some of his preparations. This accounts, in part at least, for the different formulas which appear for some of these preparations. This variation in formulas was probably due to the exhaustion, at times, of his stock of certain favorite drugs when other similar drugs were substituted, and also to changes he made as he ac- quired greater and more varied experi- ence. A man by the name of Beach imitated Thomson in his treatments, though his methods were less drastic, and he found- ed what is now known as the Eclectic school of medicine. The Thomsonians and the Eclectics were soon at war, and both again were opposed by the "regu- lars." The name Thomson is often spelled with a "p" (Thompson), but it appears in his work without the "p," hence the spelling Thomson and Thomsonian used in this work. The following is a list of the reme- dies : "Number one" (No. 1) is lobelia (emetic herb). This was used in three forms from the Guide and the Materia Medica). viz. : 1. Powder of the leaves and pods. 2. Tincture of the green herb (sec Tincture of Lobelia). 3. Mixture of powdered seed, l / 2 ounce or about a large spoonful, with the same quantity of powdered capsi- cum, a teaspoonful of ladies' slipper root, and 4 fluidounces of No. 6, PHARMACEUTICAL PREPARATIONS. 447 The powdered herb is dispensed un- less one of the other forms is wanted. "Number two" (No. 2.) (according to the Guide and the Materia Medica) is powdered capsicum, although red pep- pers, black pepper and ginger appear also to have been used. This is used for stimulating or "warming." "Number three" (No. 3) is to scour the stomach and bowels, and remove ''canker." This was composed (accord- ing to the Guide) of equal parts of bay- berry root bark, white pond lily root, and the inner bark of the common hem- lock, all in powder. One ounce of the powder was to be steeped in a pint of boiling water, the dose being a wine- glassful. If above is not to be had, use as a substitute sumach bark, berries or leaves, red raspberry leaves, witch-hazel leaves, marsh rosemary root, or squaw-weed or cocash; all are good for "canker" and may be used separately or together. The Thomsonian Materia Medica gives the following as "compounds" of No. 3: 1. Bayberry, powder oz. Y White pond lily root, powder. oz. Y* Water, boiling fl.oz. 16 Steep, sweeten, and add a small amount of capsicum. Sumach (rhus glabra) leaves, Red raspberry leaves, Witch-hazel leaves, Rosemary, each equal parts Red raspberry, Avens root, Marsh rosemary, all in fine powder, each equal parts Cranesbill, powder oz. 2 Witch-hazel, powder .oz. 2 Black oak bark, well rossed, powder oz. 1 Sage, Cocash (star flower), New Jersey tea, all in pow- der, each equal parts Hemlock bark. Black oak bark, Bayberry bark, all in pow- dear, each equal parts It is recommended that a small amount of capsicum be added to any compound for "canker" and colds. Thomson states that witch-hazel leaves may be used in connection with the other articles of No. 3, or they may be used alone as a substitute for the other articles, in all cases. "Number four" (No. 4) is the "Bit- ters," used to correct the bile and re- store digestion, and is composed (ac- cording to the Guide) of equal parts of bayberry root bark, poplar bark, and balmony. The kind of poplar preferred is what is known as stinking poplar, although the white poplar may be used. When any of the above are not obtain- able, bitter root (dogsbane) and ^olden seal may be used instead. The "compounds" of number four are (according to the Guide and the Ma- teria Medica) : 1. Balmony, Bayberry, Poplar bark, all in powder, each ^. .equal parts To one ounce of this add a pint of boiling water and Y* pint of alcohol. 2. Golden seal oz. 1 Poplar bark oz. 2 Black cherry bark oz. 4 Ladies' slipper oz. Y2 Capsicum teaspoonful : Use all in powder and mix well. To an ounce of this powder add 1 ounce of sugar, Y2 ^int of boiling water and 1 pint of best Holland gin. 3- Balmony, powder oz. 2 Poplar, powder oz. 2 Bayberry, powder oz. Y* Black birch, powder oz. 4 Capsicum oz. Y\ Sugar lb. 2 Take a teaspoonful night and morning in a little hot water, or an ounce may be put in 4 fluidounces of boiling water, to which add 1Y2 pints of good gin or ) West India rum. 448 STANDARD FORMULARY OF Other compounds of No. 4 are spice bitters, wine bitters, restorative and re- laxing bitters, astringent bitters, dys- peptic powder, and ladies' spice bitters or woman's friend. For the formulas for these preparations, see Bitters, Spice; Bitters, Wine; Bitters, Restora- tive and Relaxing; Bitters, Astringent; Bitters, Spice. Ladies'; and Powder, Dyspeptic. "Number live" (No. 5) is the "Syr- up," for dysentery, to strengthen the stomach and bowels, and restore weak patients. The syrup referred to is the so-called restorative syrup or cordial. See Syrup, Restorative (or restorative cordial). Other compounds of No. 5 are the following (from the Materia Medica) : Syrup for Weakly Patients.— Take 1 pound each of the roots of elecampane, spikenard and comfrey and Vz pound of boxwood flowers, bruise well together in a mortar, boil with 2 gallons for 1 hour, strain, and add while hot V2 ounce of golden seal, 2 ounces of dyspepsia powders, 4 ounces each of prickly-ash seed, acacia and slippery elm bark, all in fine powder, 8 pounds of sugar, 1 gallon of good Holland gin and V* gal- lon of Madeira wine. Syrup for Weakly Females. — Boil a large handful of comfrey roots, which have been well cleaned and bruised, with 2 quarts of water, strain and express the mixture, and to the liquid add 3 gra- ted nutmegs, 1 ounce of dyspepsia pow- ders, 1 pound of nulverized raisins, 6 pounds of loaf sugar, 1 pint of brandy, and 2 quarts of Madeira wine. When the mixture is cool, stir in the contents of 6 eggs which have previously been well beaten. Syrup for Dysentery. — Boil 1 ounce each of bayberrv bark and sumach (rhus glabra) leaves with 2 quarts of water for 1 hour, strain, add l / 2 ounce each of golden seal and clove, and when cool, 1 pint of rheumatic drops. Dysentery Syrup. — Make a strong de- coction of equal parts of bayberrv and sumach leaves, strain while hot, to a . gallon of decoction add 2 pounds of sugar, boil and skim, and add 1 ounce of golden seal and J^ ounce of clove. When cold add 3H quarts of rheumatic drops. Syrup for Dysentery or Relax. — Make a strong decoction of bayberry. or in lieu thereof sumach or marsh-rosemary, strain, and to 1 gallon of liquid add 2 pounds of brown sugar. When cold add 3 pints of hot drops (or enough to prevent souring). If necessary add more hot drops when taken. Syrup for Relax or Summer Com- plaint. — Take of poplar bark, black cher- ry bark, of the green roots [this is wording of original text], and balmony, each 1 pound, golden seal and hops, each Yi pound, boil these with 8 gallons of water and strain; then scald, add 25 pounds of sugar, remove the scum, and add while hot 1 pound of cloves. When cool add 2 gallons of rheumatic drops. Syrup to Strengthen the Stomach and Bowels. — Boil 1 pound each of poplar bark and bayberry with 2 gallons of water, strain, add 7 pounds of sugar, scald and skim it, then add y 2 pound of powdered peach or cherry stone meats. When cool add H gallon of good brandy. Mucilaginous Syrup. — Take the pith of the root of buckhorn brake, bruise it, add water, either cold or hot, and beat with a spoon until of about the consistence of white of egg. Pour off the liquid and to 1 gallon add 2 pounds of sugar, 1 quart of best brandy, 2 ounces of powdered caraway seed and 1 glass of volatile tincture. Antidyspeptic Restorative — Poplar bark lb. 5 Golden seal lb. 2 Ginger lb. 2 Balmony lb. 1 Ladies' slipper lb. 1 Clove lb. 1 Unicorn lb. I Cinnamon lb. I Capsicum lb. I Sugar lb. 15 All in fine powder ; mix well. PHARMACEUTICAL PREPARATIONS. 449 "Number six" (No. 6) was "rheumat- ic drops," also called "hot drops," to remove pain, prevent mortification, and promote a natural heat. See Tincture of Capsicum and Myrrh for the form- ula. Brown Lobelia is lobelia seed. Green Lobelia is lobelia herb. Nervine. — This preparation has been credited to Thomsonian practice : Tincture of aloes part I Ammoniated tincture of va- lerian ...parts 3 Compound tincture of cin- chora parts 4 Third Preparation of Lobelia, or "third preparation," as it is usually termed, is as follows (from the Materia Medica) : Lobelia seed, fine powder oz. 2 Capsicum, fine powder oz. 2 Cypripedium, powder oz. 1 No. 6 (tincture of capsicum and myrrh) fl.oz. 16 Shake well together, and preserve in small well-closed vials. For the third preparation and others of composition powder, see Powder, Composition. Astringent Bitters. — See Bitters, As- tringent. Restorative and Relaxing Bitters. — See Bitters, Restorative and Relaxing. Spice Bitters. — See Bitters, Spice. Ladies' Spice Bitters. — See Bitters, Spice, Ladies'. Wine Bitters. — See Bitters, Wine. Camphor Julep. — See Camphor Julep in its alphabetical order. Confection of Hollyhock. — See this in its proper alphabetical place. Antidyspeptic Conserve. — See Confec- tion of Hollyhock. Decoction of Sarsaparilla. — See in its alphabetical place. Compound Decoction of Sarsaparilla. — See in its alphabetical place. Rheumatic Liniment. — See Liniment, Rheumatic. Compound Liniment of Soap. — See Liniment of Soap, Compound. Stimulating Liniment. — See Liniment, Stimulating. Astringent Ointment. — See Ointment, Astringent. Burn Ointment. — See Ointment, Burn. Fern Ointment. — See Ointment, Fern. Healing Ointment. — See Ointment, Healing. Nerve Ointment. — See Ointment, Nerve. Tobacco Ointment. — See Ointment, Tobacco. Wax Ointment. — See Ointment, Wax. Ward's Paste. — See Paste, Ward. Pills No. 3. — See this in its alphabet- ical place. Anti-Canker Pills.— See Pills, Anti- Canker. Emetic Pills. — See Pills, Emetic. Laxative Pills. — See Pills, Laxative. Compound Lobelia Pills. — See Pills, Lobelia, Compound. Myrrh Pills.— See Pills of Myrrh. Cancer Plaster. — See Plaster, Cancer. Pitch Plaster.— See Plaster, Pitch. Strengthening Plaster. — See Plaster, Strengthening. Poultke. — See in its alphabetical place. Capsicum Poultice. — See Poultice, Cap- sicum. Catnep Poultice. — See Poultice, Cat- nep. Charcoal Poultice. — See Poultice, Charcoal. Emollient and Stimulant Poultice. — See Poultice, Emollient and Stimulant. Myrrh Poultice. — See Poultice, Myrrh. Stimulant and Astringent Poultice. — See Poultice, Stimulant and Astringent. Wild Indigo Poultice. — See Poultice, Wild Indigo. Yeast Poultice. — See Poultice, Yeast. Composition Powder. — See Powder, Composition. Cough Powder. — See Powder, Cough. Dyspeptic Powder. — See Powder, Dys- peptic. Nerve Powder. — See Powder, Nerve. Volatile Salts. — See Salts, Volatile. Bayberry Syrup. — See Syrup of Bay- berry. 450 STANDARD FORMULARY OF Garlic Syrup. — See Syrup, Garlic. Lobelia Syrup. — See Syrup of Lobelia. Restorative Syrup or Cordial. — See Syrup, Restorative. Strengthening Syrup. — See Syrup, Strengthening. iTincture of Capsicum and Myrrh. — See this in its alphabetical place. Tincture of Lobelia. — See in its alpha- betical order. Volatile Tincture. — See Tincture, Vol- atile. Thymol Iodid. Thymol av.oz. I Potassium iodid. .. .av.oz. I..gr. 70 Sodium hydrate, pure av.oz. 1 Distilled water, to make. . . .fl.oz. 19 Solution of chlorinated soda, sufficient, or about fl.oz. 58 Dissolve the solids in the water and gradually add the chlorinated soda solu- tion, collect the precipitate on filter and wash with water until free from chlo- rids. Dry the precipitate carefully at a temperature not to exceed 27 desr. C. — Cine. Acad. Pharm. The U. S. P. recognizes it under this title but gives no process. The U. S. P. VIII description reads : Dithymol- diodid, obtained by the condensation of two molecules of thymol and the intro- duction of two atoms of iodin into the phenolic groups of the thymol ; it con- tains 45 per cent, of iodin. Thymol iodid should be kept in amber-colored vials, protected from the light. Thyroid, Dry. This is recognized by the Brit. Pharm., in which the process of preparation is as follows : Remove the external fat and connect- ive tissue from thyroid glands taken from sheep immediately after killing. Cut the glands across, and reject any which contain cysts, are hypertrophied or are otherwise abnormal. Mince fine- ly the healthy elands, dry at a tempera- ture of from 32 to 38 deg. C, powder the dried product, remove all fat by treatment with petroleum ether, and again dry the residue. Dose, 3 to io grains. Tinctures. The tinctures of the U. S. P. are usually made from crude drugs by ex- traction in a percolator, using as a men- struum alcohol, or mixtures in various proportions of alcohol and water. The drug, in a more or less fine condition, is moistened with a small quantity of menstruum, transferred to a percolator, and, without pressing, is allowed to stand, well covered, for 6 hours. The drug is then oacked more or less firmly and enough menstruum is poured on to saturate it and leave a stratum of liquid above it. When the liquid begins to drop from the percolator, the lower ori- fice is closed, and, having closely cov- ered the percolator, macerated for 48 hours (sometimes 24 hours). Percola- tion is then allowed to take place slow- ly, menstruum being added gradually un- til the required amount of percolate is obtained. The kind of percolator generally used is that known as a cylindrical percola- tor which is only very slightly tapering. The percolator is best constructed of glass, as this is most convenient for re- tail pharmacy, but a percolator of any other suitable material not affected by drug or menstruum may be used. The size of the percolator selected should be in proportion to the quantity of drug extracted. When properly packed in the percolator, the drug should not occupy more than twe-thirds of its height. The percolator is nrepared for percolation by first gently pressing a small tuft of cotton into its throat, and this cotton may then be moistened with a few drops of menstruum to facilitate the passage of the first portion of percolate, which is often quite dense. The rate of flow of percolate is regu- A lated by means of a piece of rubber tubing which is attached to the lower orifice of the percolator by means of a perforated cork and a short segment of glass tubing. This rate of flow should not exceed 8 to 15 drops per minute, and by the expressions "slowly" and PHARMACEUTICAL PREPARATIONS. 451 "slow" percolation this rate is meant. A few of the tinctures, such as those derived from resinous substances, which contain a large amount of soluble mat- ter, are more conveniently and appro- priately prepared by macerating the coarsely powdered drug with the men- struum for 7 days (sometimes 3 days), in a stoppered container, occasionally agitating, then filtering through absorb- ent cotton or a plain paper filter. A few other tinctures, besides those from resinous drugs, are also prepared by maceration, such as arnica, sweet orange peel, cardamom compound, lavender compound, lemon peel, opium camphor- ated, squill and fresh herbs. The mac- eration should be conducted preferably at a temperature of about 15 to 20 deg. C. and in a shady place. The Brit. Pharm. gives the following specific directions for making tinctures : The Process of Percolation. — Moisten the drug, in a properly comminuted con- dition, with the prescribed quantity of menstruum, and set the mixture aside in a closed vessel for 24 hours. Pack the mixture in a percolator, lightly, firmly or otherwise, according to the na- ture of the drug. Pour over the con- tents, at intervals, further portions of the menstruum, always maintaining a layer of liquid above the drug, and allow percolation to proceed, slowly at first and afterwards less slowly, until a suf- ficient quantity of the menstruum has been used to produce about three-fourths of the volume of the finished tincture, or until exhaustion of the drug has been effected. When the liquid ceases to pass, remove the marc from the perco- lator and submit it to pressure. Filter the expressed liquid, if necessary, either at once or after standing, for 24 hours ; mix the nitrate with the percolate, and then add enough menstruum to produce the prescribed amount of tincture. [The U. S. P. directs percolation to be con- tinued until the whole volume of tinc- ture has been obtained, thus obviating the expression and filtration.] The Process of Maceration. — Mix the drug, in a properly comminuted condi- tion with the whole of the menstruum in a closed vessel for 7 days, agitate frequently, strain, press the marc, mix the expressed liquid with the strained liquid, and filter if necessary. [The U. S. P. directs maceration with about 90 per cent, of the menstruum for 7 days, agitating occasionally, filtering, and add- ing enough menstruum through the fil- ter to make the prescribed quantity of tincture.] The details and minor variations for the preparation of tinctures are left to the judgment of the pharmacist. A cylindrical percolator, preferably of glass or earthenware, may be employed in most cases, of such dimensions as to present to the menstruum a column of drug at least six times as high as wide. If a conical percolator be employed, the lower diameter should be not less than one-half the upper diameter. The pre- liminary treatment for 24 hours may be carried on in a closed percolator when desirable. Any necessary clarification may be effected by subsidence, filtration or both. For all tinctures for which no working formula is provided by the U. S. P. or N. F. or some other work of authority, and the strength of which is not other- wise specified by the prescriber, the N. F. directs the following general process : Drug, properly comminuted.av.oz. \ l / 2 Menstruum, to make fl.oz. 14^ The choice of the menstruum will de- pend upon the nature of the drug, and in some cases upon the uses to which the tincture is to be applied. In general, it may be stated that, if the useful con- stituents are soluble in alcohol, and but slightly or not at all soluble in water, strong alcohol should be used as a men- struum. Whenever it is possible, and consistent with the intended use of the preparation, the alcoholic strength of the menstruum should be made to ap- proach that of diluted alcohol, the object being not only to exhaust the drug of 452 STANDARD FORMULARY OF all its useful constituents, but also to retain them in solution. If the drug is fibrous and can be dried and powdered without injury or loss of useful constituents, percolation is pre- ferable. If the drug is resinous, and partly or almost wholly soluble in the menstruum, or if it is fibrous and can- not well be powdered without under- going injury, maceration should be re- sorted to. In the latter case, the drug, comminuted as much as possible, should be kept in contact with three-fourths the full quantity of the menstruum, in a moderately warm and shady place — the term "moderately warm'' signifying a temperature of 15 to 20 deg. C. — for two weeks, with oc- casional agitation; the liquid portion is then removed by pressure, and the resid- ual marc displaced with sufficient men- struum, either in a funnel containing a cotton filter, or by remaceration and ex- pression, until the full quantity of tinc- ture is obtained, but in the case of re- maceration, this should be done with several portions of the menstruum. The process of preparing tinctures by percolation having been devised with the primary object of securing with celerity and economy products of practically uniform and reliable com- position, and having replaced the older, and, in other respects, equally efficient, process of maceration, . the lat- ter may be resorted to in any case, if economy or time is no object, or if for other reasons it is desirable to resort to maceration, pro- vided this "alternative method" is car- ried out as follows : Reduce the dm? to the finest practi- cable division, and having weighed out the specified quantity, place it into a stoppered bottle, and add the specified menstruum in quantity equal to the to- tal volume of tincture to be made. Then macerate for at least two weeks, in a moderately warm and shady place. When required for use, decant the clear liquid and filter it through paper; express the residual marc, and having filtered the expressed liquid through the same filter, mix the clear filtrates. For the preparation of the homeo- pathic tinctures, see Tinctures, Homeo- pathic. The above remarks and directions al- lude more particularly to tinctures pre- pared from dry drug with alcohol or water or mixtures consisting essentially of one or both of these substances. For tinctures prepared with mixtures of al- cohol and ether, see Tinctures, Ethereal. For tinctures prepared from fresh or undried drugs, see Tinctures of Fresh Herbs and Tinctures, Homeopathic. Tinctures made with aromatic spirit of ammonia or ammonia mixtures are called ammoniated or volatile tinctures. Examples are the amoniated tinctures of guaiac and valerian. Tincture of Aconite. (Tincture of Aconite Root.) I. Aconite root, No. 60 powder (containing not less than V2 per cent, of aconitine).av.oz. \Y\ Alcohol, water, each, to make fl.oz. 16 Mix the alcohol and water in the pro- portion of 7 volumes of the former to 3 of the latter. Moisten the drug with 5 fluidounces of this menstruum, transfer it to a percolator, and, without pressing the powder, allow it to stand, well cov- ered, for 6 hours; then pack it very firmly and pour on enough menstruum to saturate the drug and leave a strat- um above it. When the liquid begins to drop from the percolator, close the low- er orifice, and having closely covered the percolator, macerate for 48 hours. Then allow percolation to proceed slowly, gradually adding menstruum until 16 fluidounces of liquid are obtained. The product should contain, when as- sayed, 0.05 ether soluble alkaloids in 100 mils.— U. S. P. The tincture of the U. S. P. 1890 was 3 l / 2 times the strength of the above, which fact may lead to considerable confusion. PHARMACEUTICAL PREPARATIONS. 453 Aconite root, No. 40 powder.gr. 365 Alcohol, water, each, to make fl.oz. 16 Extract the drug by percolation, using a menstruum composed of 3 volumes of alcohol and 1 of water. — Brit. Pharm. It will be noted that the U. S. P. preparation is twice as strong as this. It is also to be remarked that the prep- aration of the Brit. Pharm. 1885 was 2}/ 2 times as strong as this preparation. III. Aconite, coarse powder av.oz. i l / 2 Water fl.oz. s l / 2 Alcohol fl.oz. 13 Mix, macerate for 7 days, agitating occasionally, strain with expression, and filter. — Germ. Pharm. IV. For the homeopathic and Eclec- tic tinctures, see Tincture of Aconite Root. Tincture of Aconite, Fleming's. I. Aconite (root), fine powd.. av.oz. 11 24 Alcohol, to make fl.oz. 16 Moisten the aconite with enough alco- hol to render it distinctly damp and to maintain it so after 24 hours' macera- tion in a well-covered vessel. Then pack it tightly in a percolator, and per- colate it slowly, in the usual manner, with alcohol, until 16 fluidounces of tincture are obtained. This preparation is still prescribed by many physicians. It is recommended that their attention be directed to the official fluid extract and tincture of aconite, so that the above preparation may be grad- ually abandoned. II. When this preparation is required for immediate use, and it is not other- wise available, it may be prepared in the following manner: Fluid extract of aconite (U. S. P.) fl.oz. 7 Alcohol y fl.oz. 3 Mix them. Tincture of Aconite Leaf. L Aconite leaves, moderately fine powder av.oz. 2^4 Diluted alcohol, to make. . .fl.oz. 16 Moisten the drug with 1 fluidounce of the menstruum, macerate for 24 hours, pack firmly in a percolator, and gradually pour diluted alcohoj until 16 fluidounces of percolate are obtained. — U. S. P. i860. II. Aconite leaves, recently dried, fine powder av.oz. 2 Diluted alcohol, to make. . .fl.oz. 16 Prepare by percolation or maceration. — Eclectic. Tincture of Aconite Boot. I. Dry drug, No. 40 powder. .. .gr. 730 Alcohol, to make fl.oz. 16 Prepare by percolation. This is a ix tincture. See Tinctures, Homeopathic. This preparation may be made by di- luting 2 volumes of \J. S. P. tincture with 5 volumes of alcohol. — Homeo- pathic. Dilutions are made with dispensing alcohol. See Dilutions, Homeopathic. For the regular tincture of aconite root, see Tincture of Aconite. II. Aconite root, fine powder, .av.oz. 6 Diluted alcohol, to make. .. .fl.oz. 16 Prepare the tincture by percolation or maceration. — Eclectic. Tincture of Agaric. (Tincture of Boletus Laricis.) Drug (the dried fungus) . . . .gr. 730 Distilled water fl.oz. 6 l / 2 Alcohol fl.oz. 10K This is intended to make 16 fluid- ounces. See Tinctures, Homeopathic ; for method of preparation. This makes a ix tincture. Dilutions: 2x is to be made from 1 volume of tinc- ture, 3 of distilled water, and 6 of al- cohol; 3x and higher are to be made with dispensing alcohol. — Homeopathic. Tincture of Aloes. I. Purified aloes, No. 40 powd..gr. 730 Licorice r't, No. 40 powd. av.oz. 2>Va Diluted alcohol, to make. . .fl.oz. 16 Macerate the drugs in a stoppered container, in a moderately warm place, with 12 fluidounces of menstruum, for 7 days, agitating occasionally; then filter 454 STANDARD FORMULARY OF through absorbent cotton or a plain pa- per filter, and when the liquid has drained off completely, pass enough di- luted alcohol through the residue to make 16 fluidounces of filtrate.— U. S. P. II. Extract of barbadoes aloes.. gr. 182 Fluid extract of licorice, Brit. Pharm fl.dr. 19 Diluted alcohol, to make . . . fl.oz. 16 Mix the extract in a closed vessel with 13 fluidounces of diluted alcohol, set aside for 48 hours, agitate occasionally until the extract is dissolved, add the fluid extract, filter, and pass enough diluted alcohol through the filter to make the product measure 16 fluid- ounces.— Brit. Pharm. III. Aloes, coarse powder av.oz. 3 Water fl.oz. 3 l / 2 Alcohol fl.oz. 13 Mix, macerate for 7 days, agitating occasionally, and filter. Tincture of Aloes, Compound. Aloes, coarse powder gr. 195 Rhubarb, cut moderately fine.gr. 32 Gentian, cut moderately fine.gr. 32 Zedoary, cut moderately fine.gr. 32 Spanish saffron gr. 32 Water fl.oz. 3^ Alcohol fl.oz. 13 Macerate the drugs with the alcohol and water for 7 days, agitating occasion- ally, strain with expression, and filter. — Germ. Pharm. Tincture of Aloes and Myrrh, which see, is also called "compound tincture of aloes." Tincture of Aloes and Myrrh. (Com- pound Tincture of Aloes — Elixir Proprietatis.) Purified aloes gr. 730 Myrrh gr. 730 Licorice root gr. 730 Alcohol, water, each, to make fl.oz. 16 Extract the drugs, all in No. 40 pow- der, with a mixture of 3 volumes of alcohol and 1 of water, using the same method as for tincture of aloes. N. F. In the U. S. P. prior to 1890, there was no licorice in this formula. Without the licorice, and with the addi- tion of 360 grains of Spanish saffron, the preparation is quite like elixir pro- prietatis. This latter is somewhat differ- ent again from elixir proprietatis Para- celsi (or Elixir of Aloes, Acid, which see). Tincture of Ambergris. (Tinctura Ambra Grisea.) Drug gr. 18 Alcohol, to make fl.oz. 4 Macerate for about 7 days, agitating frequently, and filter. — Homeopathic. This is a 2x tincture. Dilutions are made with dispensing alcohol. See Di- lutions, Homeopathic. Tincture of American Ivy. (Tincture of Virginia Creeper — Tincture cf Ampelopsis Quinquefolia.) Fresh drug (bark and young twigs), containing solids... gr. 730 (plant moisture av.oz. 5) Alcohol fl.oz. 1 1^4 — Homeopathic. This is intended to make 16 fluid- ounces. It makes a ix tincture. See Tinctures, Homeopathic, for method of preparation. Dilutions : 2x is to contain 1 volume of tincture, 2 of distilled water, and 7 parts of alcohol ; 3x and higher are to be made with dispensing alcohol. Scv Dilutions, Homeopathic. Tincture, Antacrid. (Antacrid Mix- ture — Dysmenorrhea Mixture — Fenner's Guaiac Mixture — Falk's Antacrid Mixture or Tincture — Griffith's Guaiac Mixture.) Mercuric chlorid gr. 40 Guaiac resin, fine powder... av.oz. 2. .gr. 80 Canada turpentine (balsam of fir) av.oz. 2. .gr. 80 Oil of sassafras fl.dr. 4 Alcohol, to make fl.oz. 16 Introduce the guaiac and the turpen- tine into a flask, together with 12 fluid- ounces of alcohol, cork the flask loosely, and heat the contents, on a water bath, slowly to boiling. Then cool the flask, and filter the contents through a small filter. Dissolve the mercuric chlorid in 4 fluidrams of alcohol, and add this so- lution, as well as the oil, to the filtrate. Lastly, pass enough alcohol through the ^ PHARMACEUTICAL filter to make the product measure 16 fluidounces. Each fluidram contains nearly y$ gr. of mercuric chlorid. The dose of this preparation is about 10 to 20 minims. Tincture, Antihysteric. (Antihys- teric Drops.) Tincture of asafetida fl.oz. 4 Tincture of valerian fl.oz. 2 Tincture of castor (Cana- dian) fl.oz. 2 Tincture of opium fl.Ar.6y2 — H. Tincture, Antiperiodic. (Warburg's Tincture — Tincture Antifebrilis.) 1. Without aloes. Rhubarb gr. 58 Angelica seed gr. 58 Elecampane gr. 29 Spanish saffron gr. 29 Fennel gr. 29 Prepared chalk gr. 29 Gentian gr. 15 Zedoary gr. 15 Cubeb gr. 15 Myrrh gr. 15 Camphor gr. 15 White agaric gr. 15 Opium gr. 2 Black pepper gr. 3 Cinnamon gr. 6 Ginger gr. 6 Quinine sulfate gr. 145 Alcohol, distilled water, each, to make fl.oz. 16 Reduce all the drugs, with the excep- tion of the quinine, to a moderately coarse (No. 30) powder, and digest the powder with 14 fluidounces of a men- struum composed of 3 volumes of alco- hol and 2 of water, in a glass flask pro- vided with an upright condenser, on a water bath, at a temperature not higher than 150 deg. C. during 12 hours, care- fully avoiding loss of alcohol by vapor- ization. After cooling, strain the liquid by expression, and wash the residue with enough of the same menstruum, again expressing, to make 16 fluidounces of liquid. In this dissolve the quinine sul- fate, by the aid of a gentle heat, if nec- essary. Then filter the tincture through paper. — N. F. Each fluidounce contains 9 gr. of qui- nine sulfate. PREPARATIONS. 455 2. With aloes. Extract of aloes, U. S. P....gr. 2> 2 Antiperiodic tincture, without aloes fl.oz. 4 Dissolve the extract in the tincture. Each fluidounce contains 8 gr. of ex- tract of aloes, equal to about 15^2 gr. of aloes. This preparation (containing aloes) is to be dispensed when "Warburg's Tinc- ture," without further specification, is ordered. Dosage. — This depends on the kind of tincture used, whether with aloes or without, and the intended purpose, and varies from 1 to 4 fluidrams. The larg- er quantity is given • when ' Dr. War- burg's original directions are followed for administering the remedy in remit- tent fevers, which were as follows : One-half ounce to be given without di- lution, after the bowels have been evac- uated by any convenient purgative, all drink being withheld. After 3 hours, another half ounce is to be given. The original formula directed by Dr. Warburg contained the old Confectio Damocratis as one of the ingredients. This is a very complex preparation, many of the constituents of which are unobtainable at the present day. The formula of the Brit. Form, is al- most the same as that of the N. F., No. 1. Tincture of Arbor Vitse. (Tincture of Thuja.) Fresh drug (leaves and twigs), containing solids, .gr. 730 (plant moisture, av.oz. 2^4) Alcohol fl.oz. 14^ — Homeopathic. This is intended to make 16 fluid- ounces. See Tinctures, Homeopathic, for method of preparation. This is a ix tincture, from which dilu- tions are to be made with dispensing alcohol. See Dilutions, Homeopathic. Tincture of Arnica. (Tincture of Leopard's Bone.) Tincture of arnica of the U. S. P. is tincture of the flowers ; the tincture of arnica of the Brit. Pharm. is tincture of 456 STANDARD FORMULARY OF arnica root, which see; the tincture of ar- nica of the Eclectics and Germ. Pharm. is tincture of arnica flowers; see Tinc- ture of Arnica. Tincture of Arnica. (Tincture of Arnica Flowers.) I. Arnica flowers, No. 20 pow- der av.oz. Wa Diluted alcohol, to make...fl.oz. 32 Macerate the drug with 16 fluidounces of diluted alcohol in a closed vessel, in a moderately warm place, for 3 days, with occasional stirring, and express strongly. Repeat this operation twice successively with 8 fluidounces of dilu- ted alcohol, macerating 24 hours each time; then having ascertained the vol- ume of the united expressed liquids, macerate- the residual marc for 6 hours with, enough menstruum to make ap- proximately 32 fluidounces, and express as before. Mix the expressed liquids, filter through paper, and pass enough diluted alcohol through the filter to make 32 fluidounces of filtrate. — U. S. P. The drug may be expressed conve- niently by means of a tincture press. II. Arnica flowers Diluted alcohol, to make Prepare by percolation tion. III. Arnica flowers Water Alcohol fl.oz. 13 Mix, macerate for 7 days, agitating occasionally, strain with expression and filter. — Germ. Pharm. Tincture of Arnica Root. (Tincture of Arnica, Brit. Pharm.) I. Arnica root, No. 40 powder.gr. 720 Alcohol, water, each, to make fl.oz. 16 Mix the alcohol and water in the pro- portion of 13 volumes of the former to 7 of the latter. Moisten the drug with 2^2 fluidounces of menstruum, macerate for 24 hours, pack firmly in a cylin- drical percolator, and gradually pour on .av.oz. .fl.oz. or macera- av.oz. i x / 2 • fl.oz. zV 2 the above menstruum until 16 fluid- ounces of percolate are obtained. II. Arnica root, No. 40 powd...gr. 365 Alcohol, water, each, to make fl.oz. 16 Extract the drug with a mixture of 3 volumes of alcohol and I of water. — Brit. Pharm. Tincture, Aromatic. I. Cinnamon (Cassia) gr. 640 Ginger gr. 260 Galangal root gr. 130 Clove gr. 130 Cardamom gr. 130 Alcohol, water, each, to make fl.oz. 16 Reduce the drugs to a moderately coarse (No. 40) powder, and percolate it, in the usual manner, with a mixture of 2 volumes of alcohol and 1 of water, until 16 fluidounces of percolate are ob- tained. This preparation is almost identical with that which is official in the Germ. Pharm.— N. F. For a slight modification of the above, see Syrup of Yerba Santa, Aromatic, No. IV. II. Cassia cinnamon, coarse powder av.oz. V/2 Ginger, cut moderately fine..gr. 260 Galanga, cut moderately fine.gr. 130 Clove, cut moderately fine...gr. 130 Cardamom, bruised gr. 130 Alcohol av.oz. nj4 Water av.oz. 3^ Mix, macerate for 7 days, agitating occasionally, express and filter. — Germ. Pharm. Tincture of Asafetida. I. Asafetida, well bruised. .. .av.oz. 3 l /i Alcohol, to make fl.oz. 16 Macerate the drug with 12 fluidounces of alcohol, in a stoppered container in a warm place, for 3 days, agitating fre- quently, then filter through absorbent cotton or a plain paper filter, and when the liquid has drained off completely, PHARMACEUTICAL PREPARATIONS. 457 pass enough alcohol through the resi- due in the filter to make 16 fluidounces of nitrate.— U. S. P. The drug used must not be the com- mercial powder, but should be the whole gum reduced to coarse powder by con- tusion. The only practical difference between this preparation and that of the Brit. Pharm. is that in the latter the drug is extracted with a mixture of 3 volumes of alcohol and 1 of water. II. Asafetida, coarse powder, .av.oz. 2^4 Alcohol fl.oz. 16 Mix, macerate for 7 days, agitating occasionally, and filter. — Dan., Swed., and Norw. Pharms. III. Homeopathic : This is one-half the strength of the U. S. P. preparation and may be made from the latter by adding to it an equal volume of alcohol. This makes a ix tincture. Dilutions may be made from this by adding dispensing alcohol. See Dilutions, Homeopathic. Tincture of Asafetida, Compound. Asafetida gr. 180 Lupulin gr. 180 Stramonium seed gr. 180 Valerian root gr. 180 Alcohol fl.oz. 20 Mix the drugs, reduce to coarse pow- der, add the alcohol, macerate for 14 days, strain, express and filter. — Eclec- tic. Tincture, Asiatic. Opium av.oz. I Camphor av.oz. 1 Capsicum, powder av.oz. 1 Oil of clove fl.oz. 1 Hoffmann's anodyne fl.oz. 16 Mix, macerate for 10 to 20 days, and filter or decant the clear liquid. This is used for cholera, the dose be- ing 20 to 60 drops every 2, 3 or 4 hours in sweetened water. Tincture of Asparagus. Fresh drug (the young shoots), containing solids.. gr. 730 (plant moisture, av.oz. 6 2 /z) Alcohol fl.oz. 10^ — Homeopathic. This is intended to make 16 fluid- ounces. It is a ix tincture. See Tincture, Homeopathic, for method of preparation. Dilutions : 2x is to be made from 1 volume of tincture, 3 of distilled water, and 6 of alcohol; 3x and higher are made with dispensing alcohol. See Di- lutions, Homeopathic. Tincture of Avena Sativa. (Tincture of Oat.) I. Fresh drug (seed) contain- ing solids gr. 730 (plant moisture, av.oz. 3.9) Distilled water fl.oz. 2*/i Alcohol fl.oz. io^4 — Homeopathic. This is intended to make 16 fluid- ounces. It makes a ix tincture. See Tinctures, Homeopathic, for method of preparation. Dilutions : 2x are to be made from 1 volume of tincture, 3 of distilled water, and 6 of alcohol; 3x and higher are to be made with dispensing alcohol. See Dilutions, Homeopathic. II. An Eclectic formula is to prepare a strong tincture by crushing the entire plant when the grain is "in the milk," covering with alcohol, macerating 14 days, expressing, and filtering. Tincture of (Honey) Bee. (Tincture of Apis mellifica.) I. Bees, containing solids gr. 730 (moisture, av.oz. 2^) Glycerin fl.oz. 2> Z A Distilled water fl.oz. 2>Va Alcohol fl.oz. 7 — Homeopathic. This is intended to make 16 fluid- ounces. In preparing the tincture, the requisite amount of live bees should be put into a clean, wide-mouthed bottle; after irri- tating them by shaking, the menstruum should be poured in, and the whole al- lowed to macerate for 10 days, agitating twice daily. The resulting tincture should be poured off and filtered. The bees should not be pressed, as only the contents of the poison sac is desired, 458 STANDARD FORMULARY OF but the tincture takes up in solution much of the animal fluids, besides honey from the abdomen and pollen adhering to the antennae. The drug strength of the tincture varies, depending on the season of the year when the bees are secured. When they are dormant, their poison is supposed to be less virulent. Dilutions: 2x is to contain I volume of tincture, 4 of distilled water, and 5 of alcohol; 3x and higher are to be made with dispensing alcohol. See Di- lutions, Homeopathic. II. The Eclectic formula is slightly different from the preceding and is as follows : Collect a quantity of living honey-bees in a bottle, agitate the latter so as to irritate them and then cover them with alcohol ; after a few days, the liquid is ready for use. Tincture of Belladonna. The tincture of belladonna of the U. S. P. is derived from the leaves, while that of the Brit. Pharm. is derived from the root and is prepared as follows : Fluid extract of belladonna root, Brit. Pharm fl.oz. 1 Alcohol fl.oz. g l A Water fl.oz. 5 l / 2 Mix, set aside for 24 hours, and filter. See also Tincture of Belladonna Leaves. Tincture of Belladonna Leaves. Belladonna leaves, No. 60 powder (containing not less than 0.3 per cent of al- kaloids) av.oz. \Y\ Diluted alcohol, to make. . .fl.oz. 16 Moisten the drug with 5 fluidrams of diluted alcohol, transfer it to a perco- lator, and without pressing the drug, allow it to stand, well covered, for 3 hours ; then pack it firmly and pour on enough diluted alcohol to saturate the drug and leave a stratum above it. When the liquid begins to drop from the per- colator, close the lower orifice, and, hav- ing closely covered the percolator, mac- erate for 24 hours. Then allow perco- lation to proceed slowly, gradually pour- ing on diluted alcohol, until 16 fluid- ounces of percolate are obtained. Tincture of belladonna leaves, when assayed, should contain 0.035 gm. of alkaloids in 100 cc. — U. S. P. Tincture of Benzoin. (Simple Tinc- ture of Benzoin.) I. Benzoin, No. 40 powder. . . .av.oz. 2>Ya Alcohol, to make fl.oz. 16 Triturate the drug with 4 fluidounces of alcohol until a uniform magma is ob- tained. Transfer this to a stoppered container with 'the aid of 8 fluidounces of alcohol, and set it aside in a mod- erately warm place, agitating frequently, for 3 days. Then transfer the mixture to a filter paper, and, when the liquid has drained off completely, pour on the residue alcohol enough to make 16 fluid- ounces of filtrate. — U. S. P. The benzoin used should not be the ordinary, commercial powder, but should be a good quality of whole gum reduced to powder by contusion. II. Benzoin, powder gr. 730 Alcohol, to make fl.oz. 16 Macerate the benzoin with 13 fluid- ounces of alcohol for 24 hours, agitating frequently, then filter and add alcohol through the filter to make the process measure 16 fluidounces. — Brit. Form. III. Siam benzoin, coarse powd.av.oz 2^ Alcohol fl.oz. 14^2 Mix, macerate for 7 days, agitating occasionally, and filter— Germ, and Austr. Pharms. Tincture of Benzoin, Comp. (Friar's, Turlington's, Wade's, Persian, Swedish, or Commander's Balsam — Traumatic Elixir or Balsam — Balsamic Tincture — Jesuit's Drops.) I. Benzoin av.oz. 2^2 Storax „ av.oz. 2 Tolu balsam av.oz. 1 Purified aloes av.oz. y 2 Alcohol, to make fl.oz. 24 Triturate the benzoin and aloes with 6 fluidounces of alcohol until a uniform PHARMACEUTIC magma is obtained. Transfer this to a stoppered container with the aid of 12 fluidounces of alcohol, add the storax and balsam, and set the mixture aside in a moderately warm place, shaking frequently, for 3 days; then transfer it to a paper filter, and when the liquid has drained off completely, pour on enough alcohol to make 24 fluidounces of filtrate. -U. S. P. See also Balsam, Friar's. II. Benzoin, coarse powder gr. 730 Prepared storax av.oz. 1% Tolu balsam gr. 185 Socotrine aloes gr. 135 Alcohol, to make fl.oz. 16 Macerate the drugs with 13 fluid- ounces of alcohol for 2 days, agitating frequently, filter, and pass enough alco- hol through the filter to make the fil- trate measure 16 fluidounces. — Brit. Pharm. Tincture of Benzoin, Concentrated. This is the same as Extract, Fluid, of Benzoin. Tincture of Birch Tar. Hebra's (in D. and H.) : Oil of lavender flowers part I Oil of rue part 1 ' Oil of rosemary part 1 Rectified birch tar parts 25 Stronger ether parts ?j& Alcohol parts $ All parts are by weight. Tincture, Bitter. (Tinctura Amara — Stomachic Tincture — Bitter Stom- achic Drops — Stomach Drops — Magen Tropfen — Bittere Magen Tropfen.) I. Gentian av.oz. 2^2 European centaury herb, .av.oz. 2^2 Bitter orange peel av.oz. 2 l / 2 Zedoary root . . . . ...gr. 384 Alcohol Water, Of each to make fl.oz. 48 Reduce the drugs to moderately coarse powder and percolate it in the usual manner with a mixture of 2 volumes of alcohol and 1 of water until 48 fluid- ounces of percolate are obtained. — N. F. This makes a preparation practically identical with that of the Germ. Pharm. AL PREPARATIONS. 459 II. Gentian, cut moderately fine av.oz. 3 European centaury, cut mod- erately fine av.oz. 3 Bitter orange peel, cut mod- erately fine av.oz. 2 Orange berries, coarse pow- der av.oz. 1 Zedoary, cut moderately fine av.oz. 1 Water av.oz. 12^2 Alcohol av.oz. 37^ Mix, macerate for 7 days, agitating occasionally, strain with expression, and filter. — Germ. Pharm. III. Buckbean leaves av.oz. y 2 European centaury av.oz. y 2 Gentian av.oz. y 2 Bitter orange peel av.oz. y 2 Sodium carbonate, crystal, .av.oz. % Cinnamon water, spirituous (Germ. Pharm. or No. Ill) av.oz. 25 Digest for 3 days, agitating occasion- ally, express and filter. — Austr. Pharm. IV. The preparations of the Norw. and Dan. Pharms. differ from the above mainly in containing wormwood. The Norwegian preparation is as follows : Anise gr. 65 Orange berries .gr. 200 Buckbean gr. 200 Gentian gr. 200 Wormwood av.oz. 1^2 Water fl.oz. 4 Alcohol fl.oz. 123^ Reduce the drugs to coarse powder, macerate in the mixed alcohol and water for 7 days, agitating occasionally; then express and filter. The Danish preparation is as follows : Anise gr. 45 Orange berries gr. 165 Blessed thistle gr. 165 Gentian root gr. 165 Wormwood av.oz. \ x /z Water fl.oz. 4 Alcohol fl.oz. I2Y 2 Prepare like the preceding. These two preparations are called "bitre draaber" and are akin to the compound tincture of wormwood of the Swed. Pharm. See Tincture of Worm- wood, Compound. 460 STANDARD FORMULARY OF Tincture of Black Cohosh. (Tincture of Cimicifuga or Actsea Race- mosa.) Black cohosh, No. 40 powd.av.oz. 3% Alcohol, to make fl.oz. 16 Moisten the drug with 1 fluidounce of alcohol, transfer it to a percolator, and without pressing the drug, allow it to stand, well covered, for 6 hours; then pack it firmly and pour on enough men- struum to saturate the drug and leave a stratum above it. When the liquid be- gins to drop from the percolator, close the lower orifice, and having closely covered the percolator, macerate for 24 hours. Then allow percolation to pro- ceed slowly, pouring on enough alcohol to make 16 fluidounces of percolate. — N. F. The preparation of the Brit. Pharm. is one-half the strength of that of the N. F. The menstruum is also alco- hol. Tincture of Black Cohosh, Comp'd. (Compound Tincture of Cimici- fuga.) Tincture of blackcohosh fl.oz. 5 Tincture of blood root fl.oz. 2.^/2 Tincture of poke fl.oz. 1 — Eclectic. The Eclectic tinctures are intended for this mixture. This mixture may be extemporized if desired by mixing Fluid extract of black co- hosh fl.oz. 1 Fluid extract of blood root, .fl.dr. 4 Fluid extract of poke root. . .fl.dr. 2 Diluted alcohol, to make fl.oz. 8 Tincture of Bloodroot. (Tincture of Sanguinaria.) I. Bloodroot, No. 60 powder. av.oz. i^4 Hvdrochloric acid fl.dr. \y 3 Alcohol, water, each, to make fl.oz. 16 Mix the alcohol and water in the pro- portion of 3 volumes of the former to 2 of the latter. Moisten the drug with the hydrochloric acid mixed with four fluidrams of this menstruum, transfer it to a percolator, and without pressing the drug, allow it to stand, well covered, for 6 hours; then pack it firmly and pour on enough menstruum to saturate the drug and leave a stratum above it. When the liquid begins to drop from the percolator, close the lower orifice, and, having closely covered the percolator, macerate for 24 hours. Then allow per- colation to proceed slowly, pouring on enough menstruum to make 16 fluid- ounces of percolate. — U. S. P. II. Fresh drug (root), contain- ing solids gr. 730 (plant moisture, .av.oz. 5) Distilled water fl.dr. 13 Alcohol fl.oz. io^4 — Homeopathic. This is intended to make 16 fluid- ounces. See Tinctures, Homeopathic, for method of preparation. This makes a ix tincture. Dilutions: 2x are to be made from 1 volume of tincture, 3 of distilled water, and 6 of alcohol ; 3x and higher are to be made with dispensing alcohol. See Dilutions, Homeopathic. Tincture of Bloodroot, Compound. (Emetic Tincture.) Bloodroot av.oz. 1 Lobelia herb av.oz. 1 Skunk cabbage av.oz. 1 Diluted alcohol to make. . .fl.oz. 16 Extract the mixed drugs in fine pow- der by percolation or maceration. — Ec- lectic. See also next formula. Tincture of Bloodroot, Comp'd Ace- tated. (Acetous Emetic Tincture.) Bloodroot av.oz. 1 Lobelia herb av.oz. 1 Skunk cabbage av.oz. 1 Alcohol fl,pz. 1 Diluted acetic acid sufficient Reduce the drugs to moderately fine powder, extract by percolation or macer- ation with the acid so as to obtain 16 fluidounces of percolate, and to the lat- ter add the alcohol. — Eclectic. See preceding formula. Tincture of Blue Cohosh. (Tincture of Caulophyllum.) Blue cohosh, fine powder, .av.oz. 3 Alcohol fl.oz. 16 Macerate for 14 days and strain. — Ec- lectic. PHARMACEUTICAL PREPARATIONS. 461 Tincture of Blue Cohosh, Compound. Blue cohosh, fine powder. .. .gr. 580 Ergot, fine powder gr. 290 Water pepper, fine powder, .gr. 290 Oil of savin m. 160 Alcohol, to make ..fl.oz. 16 Extract the mixed drugs by percola- tion or maceration with alcohol, so that the percolate with the oil added will make 16 fluidounces. — Eclectic. Tincture of Blue Flag. (Tincture of Iris — Tinctura Iridis.) Blue flag, fine powder av.oz. iy 2 Alcohol, to make fl.oz. 16 Extract the drug by percolation or maceration. — Eclectic. Tincture of Bryony. I. Bryony, recently dried, and in No. 40 powder gr. 720 Alcohol, to make fl.oz. 16 Moisten the powder with 1^2 fluid- ounces of alcohol, macerate for 24 hours, pack firmly in a cylindrical per- colator, and gradually add alcohol until 16 fluidounces of percolate are obtained. — N. F. II. Bryony root, fresh, Alcohol, Distilled water, each sufficient Ascertain the percentage of moisture in the root by drying 100 grains of it over a water bath. Bruise the remainder, after having calculated the moisture it contains, and reckon this moisture as part of the water to form, with alcohol, a mixture equal in strength to 60 per cent, (by measure) of alcohol. Pro- duce a tincture by macerating for 7 days of such strength so that 9 l / 2 fluidounces shall represent 1 av. ounce of dried root. Add more diluted alcohol to the mixture of moist drug and alcohol to make the requisite quantity of finished tincture. — Brit. Form. Tincture of Buchu. (Tincture of Barosma.) I. Buchu, No. 20 powder av.oz. 2>Va Alcohol, water, each sufficient Mix 2 volumes of alcohol with 1 of water, moisten the drug with s 1 /^ fluid- ounces of this menstruum, and then ex- tract by percolation in the usual man- ner so as to obtain 16 fluidounces of product. — Brit. Pharm. II. Dried leaves gr. 730 Distilled water fl.oz. zVa Alcohol fl.oz. 13^ — Homeopathic. This is intended to make 16 fluid- ounces. This is a ix tincture. See Tinctures, Homeopathic, for method of preparation. This tincture is one-half the strength of that of the Brit. Pharm. Dilutions are to be made with dis- pensing alcohol. See Dilutions, Homeo- pathic. Tincture of Buckthorn. (Tincture of Frangula.) Dry drug (bark of young branches, gathered in spring and kept at least one year) gr. 730 Distilled water fl.oz. 3^ Alcohol fl.oz. 13^ — Homeopathic. This is intended to make 16 fl.oz. See Tinctures, Homeopathic, for method of preparation. This makes a ix tincture, from which dilutions are to be made with dispensing alcohol. See Dilutions, Homeopathic. Tincture of Cacao. (Tincture of Theo- broma.) Cacao beans, freshly roasted av.oz. 16 Cinnamon av.oz. 2 Tincture of vanilla, U. S. P. fl.oz. 2Y2 Diluted alcohol, to make. .. .fl.oz. 16 Reduce the cacao beans and the cinna- mon to moderately fine powder, add 16 fluidounces of diluted alcohol, macerate for 4 or 5 days, agitating occasionally, transfer to a glass percolator and perco- late, adding sufficient more of the di- luted alcohol to make the percolate, in- cluding the tincture of vanilla, measure 16 fluidounces. This is used as a flavor in some elixirs and otherwise. Tincture of Cactus Grandiflorus. (Tincture of Cereus Grandiflorus — Tinctura Cacti — Tincture of Cactus.) I. There is no tincture of this kind 462 STANDARD FORMULARY OF recognized by the U. S. P. or the Brit. Pharm. It is frequently prepared by diluting the fluid extract (which see), which is already in reality a tinc- ture, with 3 times its volume of diluted alcohol. Cactus Grandiflorus av.oz. 8 Alcohol, to make fl.oz. 16 Cut the cactus, crush in a mortar, add 12 oz. alcohol, macerate 7 days, express and percolate residue until percolate and expressed liquid measure 16 fl.ozs.— N. F. III. Fresh drug (flowers and young twigs) gr. 730 (plant moisture, .av.oz. g l / 2 ) Alcohol fl.oz. 7 l / 2 — Homeopathic. This is intended to make 16 fluid- ounces. It is a lx tincture. See Tinct- ures, Homeopathic, for method of prep- aration. Dilutions : 2x is to be made from 1 volume of tincture, 4 of distilled water, and 5 of alcohol ; 3x and higher are to be made with dispensing alcohol. See Dilutions, Homeopathic. Tincture of Calabar Bean. I. Calabar bean, No. 50 pow- der (containing 0.13 per cent ot ether-soluble alka- loids) av.oz. i^4 Alcohol, to make fl.oz. 16 Moisten the drug with 5 fluidrams of alcohol, transfer it to a percolator, and without pressing the powder, allow it to stand, well covered, for 6 hours; then pack it firmly and pour on enough alco- hol to saturate the drug and leave a stratum above it. When the liquid be- gins to drop from the percolator, close the lower orifice, and having closely covered the percolator, macerate for 24 hours. Then allow percolation to pro- ceed slowly, pouring on enough alcohol to make 16 fluidounces of percolate.— U. S. P. The product, when assayed, should contain not less than 0.013 gm. of ether- soluble alkaloids in 100 mils. The preparation of the Brit. Form, is one-half the strength of the above. The menstruum is alcohol. II. Dry drug gr. 730 Alcohol, to make fl.oz. 16 —Homeopathic. This is somewhat weaker than the U. S. P. tincture and may be prepared from the latter by mixing 2 volumes of it with 1 of alcohol. This makes a ix tincture. Dilutions are to be made from this with dispensing alcohol. See Dilu- tions, Homeopathic. Tincture of Calamus. (Tincture of Sweet Flag.) Calamus, cut moderately coarse av.oz 4 Water av.oz. 5 or fl.oz. 4^ Alcohol av.oz. 15 or fl.oz. ij%. Mix, macerate for 7 days, agitating occasionally, strain with expression and filter. — Germ. Pharm. Tincture of Calendula. (Tincture of Marigold Flowers.) Calendula (flowers), No. 20 powder av.oz. 2> l A Alcohol, to make fl.oz. 16 Moisten the drug with 10 fluidrams of alcohol, transfer it to a percolator, and without pressing the drug, allow it to stand, well covered, for 6 hours; then pack it very firmly and pour on enough alcohol to saturate the drug and leave a stratum above it. When the liquid begins to drop from the percolator, close the lower orifice, and, having closely covered the percolator, macerate for 24 hours. Then allow percolation to pro- ceed slowly, pouring on enough alcohol to make 16 fluidounces of tincture. — N. F. The preparation of the Brit. Form, differs from this only in being made with 60 per cent, aclohol as the men- struum. Tincture of Camphor. The Homeopathic tincture is the same as the U. S. P. spirit of camphor, which see. This is a lx preparation, from which dilutions are made with dispensing alco- hol. See Dilutions, Homeopathic. PHARMACEUTICAL PREPARATIONS. 463 Tincture of Camphor, Saturated. (Rubini's Camphor.) This Homeopathic preparation is satu- rated solution of camphor in alcohol containing about one-half camphor. Tincture of Cannabis. (Tincture of Indian Cannabis or of Indian Hemp 01 of Black Indian Hemp.) I. Cannabis, No. 40 powder, .av.oz. 1^4 powder av.oz. i}i Alcohol, to make fl.oz. 16 Moisten the drug with 6 fluidrams of alcohol, transfer it to a percolator, and, without pressing the drug, allow it to stand well covered for 6 hours ; then pack it very firmly and pour on enough alcohol to saturate drug and leave a stratum above it. When the liquid be- gins to drop from the percolator, close the lower orifice, and, having closely covered the percolator, macerate for 24 hours. Then allow percolation to pro- ceed slowly, pouring on enough alcohol to make 16 fluidunces of percolate. — U. S. P. II. Extract of cannabis indica, Brit. Pharm gr. 92 Alcohol, to make fl.oz. 4 Dissolve the extract in 3^ fluidounces of alcohol, filter if necessary, and add the remainder of the alcohol. — Brit. Pharm. III. Extract of cannabis indica. . . .gr. 80 Alcohol fl.oz. 4 — Germ. Pharm. (2nd). IV. Alcoholic extract gr. 23 Alcohol fl.oz. 4 — Homeopathic. The extract is to represent 8 times its weight of crude drug. This prepara- tion may be more conveniently made by mixing 1 volume of fluid extract of can- nabis indica with 9 volumes of alcohol. This makes a ix tincture, from which dilutions are to be made by the addition of dispensing alcohol. See Dilutions. Homeopathic. Tincture of Cantharides. (Tincture of Spanish Fly.) I. Cantharides, No. 60 pow- der av.oz. 1^4 Alcohol, to make fl.oz. 16 Moisten the drug with 4 fluidrams of alcohol, transfer it to a percolator, and without pressing the powder, allow it to stand, well covered, for 6 hours; then pack it very firmly and pour on alcohol enough to saturate the powder and leave a stratum above it. When the liquid begins to drop from the percola- tor, close the lower orifice, and, having closely covered the percolator, macerate for 24 hours. Then allow percolation to proceed slowly, pouring on enough alco- hol to make 16 fluidounces of percolate. — U. S. P. This preparation is twice the strength of that of the U. S. P. 1890. II. Cantharides, No. 40 powder.. gr. 92 Alcohol fl.oz. 16 Extract the drug by the maceration process. — Brit. Pharm. The U. S. P. preparation is 8 times the strength of that of the Brit. Pharm. III. Cantharides, No. 20 powder.gr. 610 Alcohol fl.oz. 16 Mix, macerate for 7 days, agitating occasionally, strain with expression and filter. — Germ. Pharm. IV. Cantharis, fine powder gr. 730 Alcohol, to make ...fl.oz. 16 — Homeopathic. See Tinctures, Homeopathic. This is about the strength of the U. S. P. preparation. It forms a ix tinct- ure, from which dilutions are made by addition of dispensing alcohol. See Di- lutions, Homeopathic. Tincture of Capsicum. (Tincture of Cayenne Pepper.) I. Capsicum, No. 50 powder. av.oz. i}£ Alcohol, water, each, to make fl.oz. 16 Mix the alcohol and water in the pro- portion of 19 volumes of the former tc 464 STANDARD FORMULARY OF i of the latter. Moisten the durg with 4 fluidrams of menstruum, transfer it to a percolator, and without pressing the powder, allow it to stand, well covered, for 6 hours ; then pack it firmly and pour on enough menstruum to saturate the drug and leave a stratum above it. When the liquid begins to drop from the percolator, close the lower orifice, and having closely covered the percolator, macerate for 24 hours. Then allow percolation to proceed slowly, pouring on enough menstruum to make 16 fluid- ounces of percolate. — U. S. P. This preparation is twice the strength of that of the U. S. P. 1890. II. Capsicum, No. 20 powder... gr. 365 Water fl.oz. 4*4 Alcohol fl.oz. 11M Mix, macerate for 7 days, agitating occasionally, strain with expression, and filter.— Brit. Pharm. [II. Capsicum, cut moderately fine gr. 730 ' Water fl.oz. 4 Alcohol fl.oz. 14^2 Mix, macerate for 7 days, agitating occasionally, strain with expression, and filter. — Germ. Pharm. IV. Capsicum, powder gr. 730 Distilled water fl.dr. &/ 2 Alcohol fl.oz. 15^ — Homeopathic. This is intended to make 16 fluid- ounces. See Tinctures, Homeopathic, for method of preparation. This makes a ix tincture (same as the U. S. P.) from which dilutions are made by the addition of dispensing al- cohol. See Dilutions, Homeopathic. Tincture of Capsicum and Myrrh. (Hot Drops — Rheumatic Drops — ''Number Six.") Capsicum, No. 20 powder... gr. 240 Myrrh, moderately coarse powder av.oz. 2, gr. 85 Water, alcohol, each, to make fl.oz. 16 Mix 'he powders with an equal bulk of clean, fine sand, and percolate, in the usual manner, with a mixture of 9 volumes of alcohol and 1 of water until 16 fluidounces of percolate are obtained. — N. F. This preparation is sometimes extem- porized by mixing equal parts of tinc- tures of capsicum and of myrrh, but such a mixture has only 80 per cent, of each of the ingredients as given in the above regular formula. This was originally a Thomsonian preparation. Thomson (in Guide and the Materia Medica) generally used 1 ounce of capsicum and 1 pound of myrrh to 1 gallon of high wines, fourth- proof brandy or other strong spirit. Other substances were somtimes added, such as bayberry, golden seal, camphor, oil of turpentine, etc. For rheumatism, itch, etc., one-fourth part of oil of tur- pentine was to be added ; for sprains and bruises, a small amount of gum camphor was to be added. For an eclectic variation of the above preparation, see Tincture of Myrrh, Compound, Tincture of Caramel. Caramel oz. 1 y 2 Alcohol fl.oz. 4 Water, to make fl.oz. 16 Dissolve the caramel in 4 ozs. water, add the alcohol and filter. Tincture of Cardamom. Cardamom av.oz. 1 % Diluted alcohol, to make fl.oz. 16 Prepare like tincture of calendula using diluted alcohol as the menstruum. — U. S. P. This preparation is twice the strength of that of the U. S. P. 1890. Tincture of Cardamom, Compound. I. Cardamom, No. 30 powder. av.oz. 2% Saigon cinnamon av.oz. 1% Caraway gr. 260 Cochineal gr. no Glycerin fl.oz. 2^2 Diluted alcohol, to make, .fl.oz. 48 Mix the glycerin with 45^2 fluidounces of diluted alcohol. Reduce the four drugs to No. 40 powder, and macerate PHARMACEUTICAL PREPARATIONS. 465 this in a stoppered container, in a mod- erately warm place, with 36 fluidounces of menstruum during 7 days, agitating occasionally; then filter through absor- bent cotton or a plain paper filter, and when the liquid has drained off com- pletely, pour on the residue, first, the remainder of the mixed liquid, and then, enough diluted alcohol to make 48 fluid- ounces of percolate. — U. S. P. II. Cardamom, bruised . ...gr. 92 Caraway, bruised gr. 92 Ceylon cinnamon, bruised. . .gr. 185 Raisins, freed from seeds... gr. 730 Cochineal, powder gr. 46 Water fl.oz. sVa Alcohol fl.oz. io>4 Mix, macerate for 7 days, agitating occasionally, strain with expression and filter.— Brit. Pharm. Tincture, Carminative. Cardamom seed, bruised. .. .gr. 500 Tincture of ginger, U. S. P. fl.oz. 2]/ 2 Oil of cinnamon m. 80 Oil of clove m. 80 Oil of caraway m. 80 Alcohol, to make fl.oz. 16 Macerate the cardamom with 12 fluid- ounces of alcohol for 7 days, decant the liquid, express the residue, filter the entire liquid, add the oils to the filtrate, and finally add - the remainder of the alcohol. — Brit. Form. Tincture of Casca. (Tincture of Ery- throphlceum.) Casca bark (Erythrophlceum guineense gr. 730 Alcohol, to make fl.oz. 16 Prepare the tincture by percolation. — Brit. Form. (2nd edition). Tincture of Cascara Sagrada. Dry drug (bark, at least 2 years old) gr. 730 Distilled water fl.oz. 6^ Alcohol fl.oz. 10^2 — Homeopathic. This is intended to make 16 fluid- ounces. See Tinctures, Homeopathic, for method of preparation. ' This is a ix tincture. Dilutions: 2x is made from 1 volume of tincture, 3 of distilled water, and 6 of alcohol ; 3x and higher are to be made with dispensing alcohol. See Dilutions, Homeopathic. Tincture of Cascarilla. Cascarilla, No. 40 powder. av.oz. 3^ Alcohol, water, each to make fl.oz. 16 Use a mixture of 3 volumes of alcohol and 1 of water as a menstruum, mois- ten the drug with 2^ fluidounces of this menstruum, and extract by percola- tion in the usual manner to obtain 16 fluidounces of percolate. — Brit. Pharm. Tincture of Castor. I. Castor (Russian preferred) .gr. 600 Alcohol, to make fl.oz. 16 Reduce the castor to as fine a condi- tion as possible, macerate with the alco- hol for 14 days, occasionally agitating, express, and filter, adding enough alco- hol through the filter to make the liquid measure 16 fluidounces. — Eclectic. II. Castor, coarse powder. Alcohol .av.oz. 2^4 .fl.oz. 16 Mix, macerate for 7 days, agitating occasionally, and filter. — Dan. Swed. and Norw. Pharms. III. Drug gr. 182 Alcohol fl.oz. 4 To make 4 fluidounces of tincture. See Tinctures, Homeopathic. This is a ix tincture. — Homeopathic. Dilutions are to be made from this by addition of dispensing alcohol. IV. The Germ. Pharm. (1st edition) recognized two preparations, one from Canadian and one from Russian castor, the preparations being otherwise iden- tical. Castor gr. 610 Alcohol fl.oz. 16 Reduce the drug to very fine condi- tion and extract by maceration with the alcohol. Tincture of Castor, Ammoniated. Castor av.oz. 1 Asaf etida gr. 240 Spirit of ammonia fl.oz. 16 Macerate in a close vessel for 7 days, 36 STANDARD FORMULARY OF agitating occasionally, express forcibly, and filter. — Eclectic. Tincture of Castor, Thebaic. (Tinc- ture of Castor with Opium.) Opium gr. 73 Ammonium carbonate gr. 210 Asafetida av.oz. 1 Castor, Canadian av.oz. 2 Dippel's animal oil gr. 7 Water fl.oz. aVa Alcohol fl.oz. I2,y 2 Reduce the solids to coarse powder, mix all, macerate for 7 days, agitating occasionally, and filter. — Swed. Pharm. Tincture of Catechu. See Tincture of Catechu, Compound. Tincture of Catechu, Comp'd. (Tinc- ture of Catechu U. S. P. 1870, and Brit, and Germ. Pharms.) T ±. Catechu, No. 40 powder gr. 730 Cassia cinnamon, No. 40 powder gr. 365 Diluted alcohol, to make. ..fl.oz. 16 Mix the powders, and without mois- tening, pack the mixture firmly in a cylindrical percolator, and gradually pour diluted alcohol upon it until 16 fluidounces of percolate are obtained. — U. S. P. 1890. This preparation was discarded in the U. S. P. 1900 for tincture of gambir, compound, which see. II. Catechu, coarse powder. . .av.oz. zVa Ceylon, cinnamon, bruised. . .gr. 365 Water fl.oz. s 3 A Alcohol fl.oz. io l /i Mix, macerate for 7 days, agitating occasionally, strain with expression, and filter.— Brit. Pharm. III. Catechu, coarse powder. . . .av.oz. 3 Water fl.oz. 3, fl.dr. 5 Alcohol fl.oz. 13 Mix, mcaerate for 7 days, agitating occasionally, strain with expression, and filter. — Germ, and Austr. Pharms. This is actually a simple tincture of catechu and is known as such by the Germ, and Austr. Pharms. The others are, however, just as much simple tinc- tures because the cinnamon is only a flavoring agent. Tincture of Celandine, Rademacher's. (Tincture of Chelidonium.) Chelidonium majus, fresh herb, Alcohol, each, equal parts by weight Contuse the herb to a pulp, add the alcohol, macerate for 2 days, agitating occasionally, express, and filter. — H. Tincture of Chamomile, Compound. (Comp. Tincture of Matricaria.) This preparation is said to be used by Eclectics : Chamomile, German av.oz av.oz. av.oz. av.oz. av.oz. av.oz. 2 1/2 y 2 Va Va H Cinnamon Ginger Galangal Clove Cardamom Diluted alcohol, to make. . .fl.oz. 16 Reduce the drugs to coarse powder and extract by percolation. Tincture of Chinoidin. I. Chinoidin Alcohol . Water .. Hydrochloric acid .av.oz. iy 2 . .fl.oz. 11 ..fl.oz. 3 ..fl.dr. 4 -Germ. Pharm. (2nd). II. Chinoidin Water Alcohol Hydrochloric acid av.oz. 1^2 fl.dr. 6 fl.oz. 14 fl.dr. 5 —Swed. Pharm. Tincture of Chirata. (Tincture of Chiretta.) Chirata, No. 40 powder gr. 720 Alcohol, water, each, to make fl.oz. 16 Mix the alcohol and water in the pro- portion of 13 volumes of the former to 7 of the latter. Moisten the powder with this menstruum, macerate for 24 hours, pack~1firmly in a cylindrical per- colator, and gradually pour menstruum upon it until 16 fluidounces of percolate are obtained.— U. S. P. 1890 and Brit Pharm. Tincture of Chloroform, Compound. Chloroform fl.oz. I Alcohol fl.oz. 4 Compound tincture of car- damom fl.oz. 5 —Brit. Form, and Brit. Pharm. i88|» PHARMACEUTICAL PREPARATIONS. 467 Tincture of Cinchona, (Tincture of Calisaya or Yellow Cinchona or Peruvian Bark — Tincture China — China Tinktur.) I. Yellow cinchona, No. 5 powder (yielding not less than 5 per cent of the alkaloids of cinchona. .. .av.oz. 3^4 Glycerin fl.oz. iJ4 Alcohol, water, each, to make fl.oz. 16 Prepare this tincture like tincture of calendula, which see, using a mixture of 10^4 fluidounces of alcohol, 4 of water, and iJ4 of glycerin as the first men- struum, to be followed by a mixture of 27 volumes of alcohol and 10 of water. The product should contain, when assayed, 0.9 gm. of the alkaloids of cin- chona in 100 mils.— U. S. P. II. The Brit. Pharm. preparation is made from red cinchona instead of the yellow as in the U. S. P. Red cinchona, No. 40, powd. av.oz. 4 Alcohol, water, each sufficient Moisten the drug with 4 fluidounces of a mixture of 3 volumes of alcohol and 1 of water, set aside for 24 hours in a closed vessel, pack in a percolator, and percolate slowly with more of the same menstruum until 13^ fluidounces of percolate are obtained. Express the marc, add the expressed liquid to the percolate, set aside for 24 hours, and filter. Assay this in the same manner as directed for liquid extract of cinchona, and dilute the filtrate with the same menstruum so that the 100 grams of the mixture shall contain 1 gram of alka- loids. III. Red cinchona, No. 2© pow- der av.oz. 3 Water fl.oz. 3^ Alcohol fl.oz. 13 Mix, macerate for 7 days, agitating occasionally, strain with expression and filter. — Germ. Pharm. V. Drug, moderately fine pow- der , gr. 730 30 Distilled water fl.oz. 3*4 Alcohol fl.oz. 13^ — Homeopathic. This is intended to make 16 fluid- ounces. See Tinctures, Homeopathic, for method of preparation. Any good cinchona bark may be used. This makes a ix tincture from which dilutions are to be made by addition of dispensing alcohol. See Dilutions, Homeopathic. Tincture of Cinchona, Comp. (Comp. Tincture of Peruvian Bark — Huxham's Tincture of Bark — Tinctura China Composita.) I. Red cinchona (yielding not less than 5 per cent, of anhydrous cinchona alka- loids) av.oz. 3 Bitter orange peel av.oz. 4 Serpentaria av.oz. 1 Glycerin fl.oz. 334 Alcohol, water, each to make fl.oz. 48 Reduce the first two drugs to No. 40 powder and the third to No. 60, and prepare like the tincture. — U. S. P. II. Bitter orange peel, dried, well bruised av.oz. 2^2 Serpentaria, No. 40 pow- der av.oz. 1 J4 Cochineal, powder gr. 70 Spanish saffron gr. 140 Tincture of cinchona, Brit. Pharm fl.oz. 24 Alcohol, water, each, to make fl.oz. 48 Mix the drugs with 6 fluidounces of water and 18 of alcohol, set aside in a closed vessel for 7 days, agitating fre- quently, strain, express the marc, mix the liquids, add the tincture of cinchona and enough of a mixture of 1 volume of water and 3 of alcohol to make 48 fluidounces, and filter. — Brit. Pharm. This differs from the formula of the preceding Brit. Pharm., which was as follows: Red cinchona, No. 40 pow- der av.oz. 5 Bitter orange peel, cut small and bruised av.oz. 2^4 Serpentaria, bruised av.oz. 1% 468 STANDARD FORMULARY OF Spanish saffron gr. 140 Cochineal gr. 70 Diluted alcohol, to make., fl.oz. 48 Extract the drugs by percolation. The newer preparation is superior be- cause it contains a definite proportion of cinchona alkaloids, and because contain- ing a larger proportion of alcohol in the menstruum which makes it a better sol- vent in this instance. III. The original formula for "Hux- ham's tincture of bark" is stated to be as follows: Red cinchona, powder av.oz. 4 Bitter orange peel av.oz. 3 Serpentaria, powder gr. 80 Spanish saffron gr. 160 Cochineal, powder gr. 80 Brandy fl.oz. 40 Digest in a warm place for 3 or 4 days, agitating frequently, then express and filter. This preparation is more like the tincture of the Brit. Pharm. than it is that of the U. S. P. Ferrated Huxham's tincture is pre- pared by dissolving 144 grains of solu- ble "scale" iron phosphate in J^ fluid- ounce of warm water, and adding this to 16 fluidounces of the tincture. IV. Red cinchona, coarse pow- der av.oz. 3 Bitter orange peel, cut mod- erately fine av.oz. 1 Gentian root, cut moderate- ly fine av.oz. 1 Cassia cinnamon av.oz. y 2 Water fl.oz. 6 Alcohol fl.oz. 213/2 Mix, macerate for 7 days, agitating occasionally, strain with expression, and filter. — Germ. Pharm. Tincture of Cinchona, Detannated. Fluid extract of cinchona, U. S. P fl.oz. 3 Alcohol fl.oz. 8 Solution of iron tersulfate. .fl.oz. 6 Ammonia wr.ter (U. S. P. or 10 p. c.) fl.oz. 6 Water, diluted alcohol, each, to make fl.oz. 16 To the ammonia water, diluted with 24 fluidounces of water, gradually add the solution of iron, tersulfate, previous- ly diluted with 40 fluidounces of water, under constant stirring. Pour this mix- ture, containing ferric hydrate as a pre- cipitate, upon a wet muslin strainer (which has been weighed, after having been wetted and deprived of the excess of water by moderate pressure), and when the liquid has drained off, return the precipitate to the vessel, and mix it intimately with about 64 fluidounces of water. Again drain it on the strainer, transfer it once more to the vessel, and treat it as before. Finally drain and press the precipitate on the strainer until it weighs 8^4 av.ounces. Mix the fluid extract of cinchona with 8 fluidounces of alcohol, and add the ferric hydrate previously prepared. Agi- tate the mixture frequently, until the tincture is deprived of tannin, which may be known by the absence of a blackish-green color when a small por- tion of the clear tincture is treated with a drop or two of tincture of iron chlo- rid. Insert a plug of absorbent cotton into a suitable percolator, and introduce the mixture. As soon as the liquid has disappeared from the surface, pour on enough diluted alcohol to make the product measure 16 fluidounces. This preparation is practically iden- tical, in strength of cinchona (without the tannin), with the official tincture of cinchona. Tincture of Cinchona, Ferrated. Comp. tincture of cinchona. fl.oz. 16 Ferric hydrate, freshly pre- cipitated av.oz. y 2 Citric acid, alcohol sufficient Citrate of iron and ammo- nium gr. 256 Mix the tincture with the hydrate, agitate occasionally until the tincture is detannated, extract the precipitate with boiling alcohol until all the alkaloid has been extracted, evaporate the solution to dryness, dissolve in a little water by the aid of a small amount of citric acid, add to the filtered liquid along with the citrate of iron and ammonium and agi- tate till dissolved. — Eclectic. PHARMACEUTICAL PREPARATIONS. 469 Tincture of Cinnamon. I. Saigon cinnamon, No. 50 powder av.oz. z z A Glycerin fl.oz. 1% Alcohol, water, each, to make fl.oz. 16 — U. S. P. Prepare this tincture exactly like tinc- ture of cinchona, which see. This preparation is twice the strength of that of .the U. S. P. 1890. II. Ceylon cinnamon, No. 60 powder av.oz. zVa Alcohol, water, each, to make fl.oz. 16 Moisten the drug with zVa fluidounces of a mixture of 1 volume of water and 3 of alcohol, and extract by percolation with the same menstruum. — Brit. Pharm. III. The preparation of the Germ, and Austr. Pharms. is a tincture of cassia, made as follows: Cassia cinnamon, No. 20 powder av.oz. 4 Water „ fl.oz. 4^ Alcohol fl.oz. lj 1 /^ Mix, macerate for 7 days, agitating occasionally, strain with expression, and filter. Tincture of Cinnamon, Compound. Cinnamon, Ceylon av.oz. y 2 Cardamom gr. 90 Prickly-ash berries gr. 90 Ginger gr. 90 Diluted alcohol, to make. .. .fl.oz. 16 Extract the mixed drugs in fine pow- der by percolation or maceration. — Ec- lectic. Tincture of (White) Clover. (Tinc- ture of Trifolium repens.) Tincture and dilutions of white clover are to be made the same as of red clover. See Tincture of Red Clover. — Homeopathic. Tincture of Coca. (Tincture of Ery- throxlyon.) I. Dry drug (leaves, carefully selected) gr. 730 Distilled water fl.oz. 8 Alcohol fl.oz. 8..fl.dr. 5 — Homeopathic. This is intended to make 16 fluid- ounces. See Tinctures, Homeopathic, for method of preparation. This makes a ix tincture. Dilutions: 2x is to be made from 1 volume of tincture, 4 of distilled water, and 5 of alcohol. See Dilutions, Homeopathic. II. Coca, coarse powder av.oz. 3 Water fl.oz. 4^ Alcohol fl.oz. iiY 2 Mix, macerate for 10 days, agitating occasionally, strain with expression, and filter. — Codex. Tincture of Cocculus Indicus. 'inc- ture of Indian Cockle.) Cocculus Indicus, No. 30 powd oz. \y 2 Diluted alcohol, to make. .. .fl.oz. 16 Saturate the powder with diluted alco- hol, and after macerating for six hours, percolate it in the usual manner with diluted alcohol until the product mea- sures 16 fluid ounces. This tincture is used almost exclu- sively for external application, to de- stroy parasites. — N. F. Tincture of Cochineal. (Tincture Coccionellse — Tincture Cocci — Tincture of Coccionella or Coceus Cacti.) I. Cochineal, powder av.oz. 1 y 2 Water fl.oz. 3^ Alcohol fl.oz. 13 Macerate for 3 days, agitating occa- sionally, and filter. — H. II. Cochineal, powder gr. 73® Diluted alcohol, to make. . .fl.oz. 16 Mix, macerate for 7 days, agitating oc- casionally, strain with expression, and filter.— Brit. Pharm. This preparation may be used for col- oring purposes, as for coloring elixirs. III. Dry drug gr. 730 Distilled water fl.oz. 8 Alcohol fl.oz. 8..fl.dr. 5 — Homeopathic. This is intended to make 16 fluid- ounces. See Tinctures, Homeopathic, for method of preparation. 470 STANDARD FORMULARY OF This makes a ix tincture. Dilutions : 2x is to be made from i volume of tinc- ture, 4 of distilled water, and 5 of alcohol. 3x is to be made from this with dispensing alcohol. See Dilutions, Homeopathic. Tincture of Coffee. (Tincture of Cof- fea.) Dry drug (the seed, using the best unroasted "Mo- cha" coffee) gr. 730 Alcohol, to make fl.oz. 16 — Homeopathic. See Tinctures, Homeopathic, for meth- of preparation. This makes a ix tincture, from which dilutions are made with dispensing al- cohol. See Dilutions, Homeopathic. Tincture of Colchicum Seed. (Tinc- ture of Colchicum, TJ. S. P. 1880.) I. Colchicum seed, No. 50 pow- der (containing not less than 0.55 per cent, of col- chicine) av.oz. iyi Alcohol, water, each, to make fl.oz. 16 Prepare this tincture like tincture of belladonna, using a mixture of 3 vol- umes of alcohol and 2 of water as a menstruum. — U. S. P. This preparation should contain 0.036 to 0.044 gm. of colchicine in 100 mils. II. Colchicum seed, No. 30 pow- der av.oz. zYa Diluted alcohol, to make. .. .fl.oz. 16 Extract by percolation. — Brit. Pharm. This preparation is rather more than i]/ 2 times the strength of that of the Brit. Pharm. 1885, which was made from 2 av. ounces of drug and enough diluted alcohol to make 16 fluidounces. III. Colchicum seed, No. 20 pow- der av.oz. 1 Water fl.oz. s l / 2 Alcohol fl.oz. 13 Mix, macerate for 7 days, agitating occasionally, strain with expression, and filter. — Germ. Pharm. Tincture of Colchicum, Compound. Colchicum seed, fine powd. av.oz. 1 ijlack cohosh, fine powder. av.oz. \ l / 2 Diluted alcohol, to make. . . .fl.oz. 16 Prepare the tincture by percolation or maceration. — Eclectic. This preparation may be extemporized by mixing 6 l / 2 fluidounces of U. S. P. tincture of colchicum seed, yy 2 fluid- ounces of U. S. P. tincture of black cohosh and 2 fluidounces of diluted al- cohol. Tincture of Colocynth. (Tincture of Bitter Apple.) I. Colocynth, with seeds, cut coarse av.oz. iH Water fl.oz. 3^ Alcohol fl.oz. 13 Mix, macerate for 7 days, agitating occasionally, strain with expression, and filter. — Germ. Pharm. II. Dry drug (pulp of the fruit, without the seeds) gr. 730 Distilled water fl.oz. 8 Alcohol fl.oz. 8. .fl.dr. 5 — Homeopathic. This is intended to make 16 fluid- ounces. See Tinctures, Homeopathic, for method of preparation. This makes a ix tincture. Dilutions: 2x is to be made from 1 volume of tincture, 3 of distilled water and 6 of alcohol. 3x and higher are to be made with dispensing alcohol. See Dilutions, Homeopathic. Tincture of Colocynth Seed, Rade- macher's. Colocynth seed av.oz. 3 Water fl.oz. 3^ Alcohol fl.oz. 125^ Wash the seed with water, dry it, re- duce to coarse powder, and add the water and alcohol. Macerate for 14 days, agitating occasionally, express, and filter. The product should weigh 14^2 av.ounces. — H. Tincture of Columbo. (Tincture of Calumtoa.) I. Columbo, No. 20 powder, .av.oz. zVa Alcohol, water, each, to make fl.oz. 16 Mix alcohol and water in the propor- tion of 3 volumes of the former to 2 of the latter. Moisten the drug with 13 fluidrams of this mixture, transfer it to PHARMACEUTICAL PREPARATIONS. 471 a percolator, and, without pressing the drug, allow it to stand, well covered, for 24 hours ; then pack with moderate pres- sure, pour on enough menstruum to sat- urate the powder and leave a stratum above it, and allow percolation to pro- ceed slowly, pouring on enough men- struum to make 16 fluidounces of perco- late.-U. S. P. On account of the large amount of extractive matter in the drug, the mac- eration is omitted. This preparation is twice as strong as that of the U. S. P. 1890. II. The preparation of the Brit). Pharm. is one-half the strength of that of the U. S. P. and is made with a mixture of 2 volumes of alcohol and 1 of water by the process of maceration. Tincture of Condurango. (Tincture of Cundurango.) Dry drug (bark) gr. 730 Distilled water fl.oz. 8 Alcohol fl.oz. 8..fl.dr. 5 - — Homeopathic. This is intended to make 16 fluid- ounces. See Tinctures, Homeopathic, for method of preparation. This makes a ix tincture. Dilutions : 2x is to be made from 1 volume of tincture, 4 of distilled water and 5 of alcohol. 3x and higher are to be made with dispensing alcohol. See Dilutions, Homeopathic. Tincture of Conium. (Tincture of Hemlock.) I. Conium (fruit, the so-called seed), No. 30 powder. . .av.oz. 2 J A Diluted hydrochloric acid m. 30 Diluted alcohol, to make. ..av.oz. 15 Moisten the powder with 6 fluidrams of diluted alcohol, previously mixed with the acid, and macerate for 24 hours; then pack it moderately in a conical glass percolator, and gradually pour diluted alcohol upon it until 15 av.ounces of tincture are obtained. II. Conium fruit, recently re- duced to No. 40 powder. av.oz. 2> l A Alcohol, water, each, to make fl.oz. 16 Extract the drug by percolation with a mixture of 3 volumes of alcohol and 1 of water. Tincture of Convallaria. (Tincture of Lily-of-the-Valley.) Lily-of-the-valley flowers and stalks, dried, No. 20 pow- der av.oz. 2 Water, alcohol, to make fl.oz. 15^2 Extract the drug by percolation, using as menstruum a mixture of 9 volumes of alcohol with 5 of water. — Brit. Form. Tincture of Copaiva. Copaiba balsam gr. 730 Alcohol fl.oz. 14J/2 — Homeopathic. This is intended to make 16 fluid- ounces. This makes a ix tincture. Dilutions are to be made from this with dispens- ing alcohol. See Dilutions, Homeo- pathic. Tincture of Copper Acetate, Rade- macher's. Copper sulfate, pure gr. 680 Lead acetate, pure, crystaL.gr. 1020 Distilled water fl.oz. 8^4 Alcohol fl.oz. 7^4 Triturate the two salts together until a smooth paste is formed, transfer this to a copper vessel, add the water, heat to boiling, allow to cool, add the alco- hol, set aside for 4 weeks, agitating fre- quently, and filter. — H.' A more expeditious process is the following : Copper acetate, crystallized, .gr. 570 Distilled water fl.oz. 9 Alcohol fl.oz. 7 Dissolve the acetate in the water pre- viously warmed, and filter. Tincture of Corn Smut. (Tincture of Ustilago Maidis.) Corn smut, fresh, containing solids gr. 730 (plant moisture, gr. 730) Distilled water fl.oz. 4^ Alcohol fl.oz. io^4 — Homeopathic. This is intended to make 16 fluid- ounces. See Tinctures, Homeopathic, for method of preparation. This makes a ix tincture. Dilutions : 2x is to be made from 1 volume of 472 STANDARD FORMULARY OF tincture, 3 of distilled water, and 6 of alcohol ; 3x and higher are to be made with dispensing alcohol. See Dilutions, Homeopathic. Tincture of Corydalis. (Tincture of Turkey Corn.) Turkey corn, fine powder, .av.oz. 3 Diluted alcohol, to make. . . .fl.oz. 16 Extract the drug by percolation or maceration. — Eclectic. Tincture of Corydalis, Comp'd. (Com- pound Tincture of Turkey Corn — Scudder's Alterative.) Turkey corn gr. 320 Yellow dock gr. 320 Tag alder bark gr. 320 Figwort herb gr. 320 Mandrake root gr. 320 Sugar av.oz. 3 Alcohol, water, each, to make fl.oz. 16 Mix the first four drugs, reduce to fine powder, and extract by percolation with diluted alcohol so as to obtain 12 fluidounces of percolate. To the man- drake in fine powder add 2^4 fluid- ounces of boiling water, macerate in a hot place for 2 hours, and express, or else obtain 2^2 fluidounces of infusion by percolation. In this liquid dissolve the sugar, and add the solution to the previously prepared tincture. — Eclectic modified. Dr. Scudder believed that water ex- tracts more of the alterative properties of mandrake than those of alcohol. Tincture of Coto. (Tincture of Para- coto.) Paracoto (No. 40 po.) av.oz. 2 Alcohol, to make fl.oz. 14^ Macerate the drug with 12 fluidounces of alcohol during 7 days ; then pour off the liquid, press the residue, and filter the united liquids through paper. Last- ly, wash the residue transferred to the filter with enough alcohol to make the product measure 14^2 fluidounces. Coto bark is derived from an unde- termined tree, probably belonging to the natural order Lauraceae, and is obtained from Bolivia. There are two varieties known, one as coto and the other as paracoto bark. True coto bark is, at times, difficult to obtain in the market. and in N. F. IV paracoto bark has been substituted for it. While they possess some useful properties in common, yet they differ materially in other respects. Hence, the paracoto bark should not be substituted for the true coto bark. — N. F. II. Coto bark, bruised gr. 730 Alcohol, to make fl.oz. 16 Macerate the drug with 16 fluidounces of alcohol for 7 days, agitating occasion- ally, express, filter, and add alcohol to make 16 fluidounces. Tincture of Couch Grass. (Tincture of Dog Grass or Triticum.) Fresh drug (root), contain- ing solids gr. 730 (plant moisture, av.oz. 3.9) Distilled water fl.oz. 2^ Alcohol fl.oz. 10K — Homeopathic. This is intended to make 16 fluid- ounces. See Tinctures, Homeopathic, for method of preparation. This makes a ix tincture. Dilutions : 2x is to be made from 1 volume of tincture, 3 of distilled water, and 6 of alcohol ; 3x and higher are to be made with dispensing alcohol. See Dilutions, Homeopathic. Tincture of Cowhage. (Tincture of Dolichos or Mucuna.) Cowhage gr. 730 Alcohol, to make fl.oz. 16 — Homeopathic. See Tinctures, Homeopathic, for method of preparation. This makes a ix tincture. Dilutions are to be made with dispensing alcohol. See Dilutions, Homeopathic. Tincture of Cramp Bark, Compound. See Tincture of Viburnum, Compound. Tincture of Cramp Bark, Vionaus. Cramp bark, coarse powd. av.oz. 1 Scullcap, coarse powder. . .av.oz. y 2 Skunk cabbage, coarse pow- der av.oz. x /2 Clove, coarse powder av.oz. *4 Capsicum, ^owder gr. 60 Sherry wine fl.oz. 32 — Eclectic. Macerate for several days, and filter. PHARMACEUTICAL PREPARATIONS. 473 Tincture of Cubeb. Cubeb, No. 30 powder. .. .av.oz. z l A Alcohol, to make fl.oz. 16 Moisten the drug with i l / 2 fluidounces of alcohol, macerate for 24 hours, then pack firmly in a cylindrical percolator, and gradually add alcohol until 16 fluid- ounces of percolate are obtained. — N. F., U. S. P. 1890, and Brit. Pharm. II. Homeopathic: This is of one-half the strength of the preceding preparation. It may be made from the latter by adding to it an equal volume of alcohol. This makes a ix tincture, from which dilutions are to be made with dispensing alcohol. See Dilutions, Homeopathic. Tincture of Cudbear. (Tinctura Persionis.) Cudbear, fine powder av.oz. 2 Alcohol, water, each, to make fl.oz. 14^ Pack the cudbear in a suitable perco- lator, and percolate it with a mixture of 1 volume of alcohol and 2 of water, until i4 l / 2 fluidounces of tincture are obtained. This preparation is intended as a col- oring agent, when a bright-red tint or -:olor is to be produced, particularly in acid liquids. — N. F. Tincture of Cudbear, Compound. Cudbear, fine powder gr. 120 Caramel av.oz. ij4 Alcohol, water, each, to make fl.oz. 16 Mix 1 volume of alcohol with 2 of water. Macerate the cudbear with 12 fluidounces of the menstruum, during 12 hours, agitating occasionally, and then filter through paper, and add the caramel, previously dissolved in 2 fluid- ounces of water. Then pass enough of the before - mentioned menstruum through the filter to make the whole measure 16 fluidounces. This preparation is intended as a col- oring agent, when a brownish-red tint or color is to be produced. — N. F. Tincture of Culver's Root. (Tincture of Leptandra — Tincture of Black- Root.) Culver's root, moderately fine powder av.oz. 3 Diluted alcohol, to make. .. .fl.oz. 16 Make into a tincture by percolation or maceration. — Eclectic. Tincture of Curare. Drug gr. 92 Distilled water fl.dr. 8 Alcohol fl.dr. 8^ — Homeopathic. This is intended to make 2 fluid- ounces. This is a ix tincture. Dilutions : 2x is to be made from 1 volume of tinc- ture, 3 of distilled water and 6 of dis- tilled water; 3X and higher are to be made with dispensing alcohol. See Di- lutions, Homeopathic. Tincture of Cyclamen. (Tincture of Sow-Bread or Hog's-Bread.) Fresh tubers av.oz. 8 Alcohol fl.oz. 16 — Eclectic. The tubers should be cut into small pieces, macerated with the alcohol for 7 to 14 days, and filtered. Prof. Scudder recommends the fresh tubers of hot-house plants. Tincture of Digitalis. (Tincture of Foxglove.) I. Digitalis, No. 60 powder, .av.oz. \Y\ Diluted alcohol, to make. . .fl.oz. 16 Prepare like tincture of cantharides, using diluted alcohol as the menstruum. This is an assayed tincture. — U. S. P. II. Brit. Pharm.: Digitalis, No. 20 powder. . .av.oz. 2 Alcohol, water, each, to make fl.oz. 15^ Extract the drug by percolation with a mixture of 7 volumes of alcohol and 4 of water. III. Digitalis, coarse powder. ..av.oz. 1 Water fl.oz. z x A Alcohol fl.oz. 13 Mix, macerate for 7 days, agitating occasionally, strain with expression, and filter. 4T4 STANDARD FORMULARY OF In the Germ. Pharm., 3rd edition, this preparation was made from fresh leaves as follows : Digitalis leaves, freshly gath- ered av.oz. 15 Alcohol fl.oz. 20^ Bruise the drug in a wedgewood mor- tar to a uniform pulp, incorporate the alcohol, allow to macerate for 7 days, then express, set the liquid aside in a cool place for 2 days, and filter. Keep protected from daylight. Tincture of Digitalis, Ethereal. Digitalis, cut very fine. .. .av.oz. 1^2 Spirit of ether fl.oz. 18^2 Mix, macerate for 7 days, agitating oc- casionally, and strain with expression. — Germ. Pharm. 2nd edition. See also Tinctures, Ethereal. Tincture of Digitalis, Fat-Free. England's process : Digitalis, freshly-ground. .. .av.oz. iji Purified petroleum benzin, Ammonia water, Diluted alcohol, each sufficient Exhaust the drug with the bezin by maceration, or maceration and perco- lation together, as may be most conve- nient. Then dry the drug, preferably by exposure to both sun and air to en- tirely remove the benzin. Then extract the drug by the U. S. P. process, con- tinuing percolation until 15M fluid- ounces of percolate are obtained. Neu- tralize the latter carefully with ammonia water, which will require about 1^ or 2 fluidrams. Then add diluted alcohol to make 16 fluidounces. The product mixes clear with water, contains no fats or free acids, and does not cause gastric disturbance. Tincture of Ergot, Ammoniated. Ergot, No. 30 powder av.oz. 4% Ammonia water fl.dr. 13 Alcohol, water, each, to make fl.oz. 16 Mix the ammonia water with 3 fluid- ounces of water and 9 fluidounces of alcohol, saturate the drug with this men- struum, and after macerating for 24 hours percolate it in the usual manner, first with the remaider of the men- struum and afterward with a mixture of two volumes of alcohol and one vol- ume of water until the product measures 16 fluid ounces. In the Brit. Pharm. 1885, diluted al- cohol was used as the menstruum. Tincture of Ergot, Ammoniated. See Tincture of Ergot. Tinctures, Ethereal. The following is the general formula of the N. F. for ethereal tinctures : Drug, properly comminu- ted av.oz. 1 Y /z Alcohol, stronger ether, each, to make ' fl.oz. 14^ Percolate the drug in the usual man- ner, but with proper precautions to avoid loss of menstruum by evaporation, with a mixture of 1 volume of stronger ether and 2 of alcohol, until 14H fluidounces of percolate are obtained. This formula is to be used, when ethereal tinctures of belladonna, castor, digitalis, lobelia, valerian, or of other drugs, are to be prepared. Tincture of Eucalyptus. (Tincture of Fever Tree or Australian Fever Tree.) I. Eucalyptus, No. 20 powder. av.oz. 3^ Alcohol, to make fl.oz. 16 Extract the drug by percolation. II. Dry drug (leaves) gr. 730 Distilled water fl.dr. 13 Alcohol fl.oz. 14. .fl.dr. . 5 — Homeopathic. This is intended to make 16 fluid- ounces. See Tinctures, Homeopathic, for method of preparation. This makes a ix tincture, from which dilutions are to be made with dispensing alcohol. See Dilutions, Homeopathic. Tincture of Euphorbia Pilulifera. Euphorbia, pilulifera, No. 40 powder av.oz. zVa Water, alcohol, to make fl.oz. 16 Prepare the tincture by percolation, using as a menstruum a mixture of 9 volumes of alcohol with 5 of water. PHARMACEUTICAL PREPARATIONS. 475 The drug is the herb of Euphorbia pilulifera collected when in flower and carefully dried. The involucral glands of the perianth are without appendages ; the mature seeds are minutely wrinkled. Tincture of Fennel, Compound. (Romershausen's Augen Essenz.) The following is the simplest formula for this preparation : Fennel seed, contused av.oz. 4 Oil of fennel drops 40 Oil of neroli drops 4 Water fl.oz. 4 Alcohol fl.oz. 11^ Macerate for several days and ex- press. — H. This was originally a secret remedy in Germany, but is now frequently com- pounded by pharmacists and sold as such. It is used by the public to pre- serve, strengthen and restore the eye- sight, -it being mixed before use with 5 volumes of soft water. Tincture of Ferrated Extract of Ap- ples. (Pomated Tincture of Iron — Tinctura or Liquor Ferri Po- mata — Tincture or Solution of Crude Malate of Iron.) Ferrated extract of apples. av.oz. V/2 Alcohol fl.dr. 1 1 Cinnamon water, to make, .fl.oz. 14H Dissolve the ferrated extract of ap- ples in n fluidounces of cinnamon wa- ter, add the alcohol, filter, and pass enough cinnamon water through the fil- ter to make 16 fluidounces. Each fluidram represents about ^ gr. of metallic iron. — N. F. This preparation is practically iden- tical with that official in the Germ. Pharm., which is made from 1 av.ounce of the ferrated extract and 9 av.ounces of the cinnamon water of the Germ. Pharm. Tinctures of Fresh Drugs. See Tinctures of Fresh Herbs. Tinctures of Fresh Herbs. ("Green," "German" or "Specific" Tinc- tures.) According to the U. S. P., tinctures of fresh (freshly-gathered) herbs, when not otherwise directed, are to be pre- pared by macerating 854 av.ounces of the fresh herb, cut, bruised or crushed with 16 fluidounces of alcohol in a closed vessel, in a moderately warm place, during 14 days, stirring occasion- ally; then express the liquid with strong pressure and filter it through a paper filter. The drug may be expressed by means of a tincture press. Tinctures of fresh drugs are in con- siderable use and hence the above gen- eral formula serves a useful purpose. The so-called "green" or "German" tinctures, sometimes also called "spe- cific" tinctures, of the market, are tinc- tures of fresh drugs. Tincture of Gambir, Compound. Gambir gr. 365 Saigon cinnamon gr. 182 Diluted alcohol, to make. . .fl.oz. 16 Macerate the gambir and cinnamon in a stoppered container, in a moderate- ly warm place, with 12 fluidounces of diluted alcohol, during 48 hours, agita- ting frequently. Then filter through absorbent cotton or a plain paper filter, and, when the liquid has drained off completely, pass enough diluted alcohol through the residue to make the filtrate measure 16 fluidounces. — U. S. P. Gamber is the so-called pale catechu and this tincture is intended as a sub- stitute for the compound tincture of catechu of former editions of the U. S. P. Tincture of Gelsemium. (Tincture of Yellow Jessamine.) I. Gelsemium, No. 60 powd.. av.oz. if£ Alcohol, water, each, to make fl.oz. 16 — U. S. P. Prepare like tincture of cantharides, using as a menstruum a mixture of 13 volumes of alcohol and 7 of water. II. Gelsemium, No. 40 powder.. gr. 730 Alcohol, water, each, to make fl.oz. 16 Mix alcohol and water in the propor- tion of 12 volumes of the former to 7 4T6 STANDARD FORMULARY OF of the latter, and extract the drug by percolation with this menstruum. — Brit. Pharm. Tincture of Gentian. Gentian, cut moderately fine av.oz. 3 Water fl.oz. 3^ Alcohol fl.oz. 13 Mix, macerate for 7 days, agitating occasionally, strain with expression, and filter. — Germ. Pharm. Tincture of Gentian, Compound. I. Gentian av.oz. 5 Bitter orange peel av.oz. 2 Cardamom av.oz. V2 Alcohol, water, each, to make fl.oz. 48 Mix 3 volumes of alcohol with 2 of water. Reduce the three drugs to No. 40 powder, moisten this with 3 fluid- ounces of menstruum, transfer it to a percolator, and, without press- ing the drug, allow it to stand, well covered, for 12 hours, then pack it moderately and pour on enough men- struum to saturate the powder and leave- a stratum above it. When the liquid begins to drop from the percolator, close the lower orifice, and, having closely covered the percolator, macerate for 12 hours; then allow percolation to proceed slowly, pouring on enough men- struum to make 48 fluidounces of per- colate.— U. S. P. II. The preparation of the Brit. Pharm. differs from that of the U. S. P. in having i$4 av.ounces of bitter orange peel and 260 grains of cardamom and in being extracted with diluted alcohol by maceration. III. Gentian Columbo Swamp milkweed .... Rhubarb Sassafras Prickly-ash berries . . Brandy, to make Prepare a tincture by the usual meth- od of percolation or maceration.— Ec- lectic. av.oz. Va av.oz. Va av.oz. Va av.oz. Va av.oz. Va av.oz. Va fl.oz. 16 Tincture of Ginger. I. Jamaica ginger, No. SO pow- der av.oz. zVa Alcohol, to make fl.oz. 16 Prepare like tincture of black cohosh. -U. S. P. II. The preparation of the Brit. Pharm. differs from that of the U. S. P. only in being made with one-half the pro- portion of drug. The Brit. Pharm. 1885 recognized two tinctures of ginger; one was made with somewhat more than 2 av.ounces of drug to the pint of tincture (one- fourth stronger than that of the present Brit. Pharm.) ; the other, called "strong tincture of ginger" (tinctura zingiberis fortior), was made with %Va av.ounces of drug to the pint of tincture. The latter is now recognized by the Brit. Form. III. Ginger, cut moderately fine.av.oz. 3 Water fl.oz. 3V2 Alcohol fl.oz. 13 Mix, macerate for 7 days, agitating occasionally, strain with expression, and filter. IV. Dry drug, Jamaica preferred.gr. 730 Alcohol, to make fl.oz. 16 — Homeopathic. See Tinctures, Homeopathic, for method of preparation. This forms a ix tincture, one-half the strength of the U. S. P. tincture, from which it may be made by mixing it with an equal volume of alcohol. Dilutions are to be made with dis- pensing alcohol. See Dilutions, Homeo- pathic. V. A cheap tincture of ginger suit- able for counter sale and saloon use may be prepared as follows: Ginger, African, powder, .av.oz. 60 Capsicum, powder av.oz. 1 Alcohol, water, each, to make fl.oz. 64 Use a menstruum composed of 3 vol- umes of alcohol and 1 of water and extract the mixed drugs by percolation or maceration. PHARMACEUTICAL PREPARATIONS. 477 Tincture of Glonoin. (Tincture of Nitroglycerin.) The Homeopathic tincture is the spir- it of glonoin, U. S. P,, and is a 2x tinc- ture. Dilutions are to be made from this with dispensing- alcohol. See Dilu- tions, Homeopathic. Tincture, Golden. See Drops, Gold. Tincture of Golden Rod, Rademach- er's. (Tincture Virgae Aurese.) Golden rod, fresh flowering- herb, Alcohol, each.. equal parts by weight Contuse the herb to a pulp, add the alcohol, macerate for 2 days, agitating occasionally, express, and filter. — H. Tincture of Golden Seal. (Tincture of Hydrastis.) I. Hydrastis, _ No. 60 powder (containing not less than 2.5 per cent, of hydrastis). av.oz. 2> l A — U. S. P. Prepare like tincture of black cohosh, using as a menstruum a mixture of 13 volumes of alcohol and 7 of water. The product, when assayed, should contain not less than 0.36 gm. of ether- soluble alkaloids in 100 mils. II. The preparation of the Brit. Pharm. is one-half the strength of the above; the menstruum is a mixture of 7 volumes of alcohol and 4 of water ; the process is percolation. Tincture of Golden Seal, Compound. Golden seal av.oz. 2 Lobelia seed av.oz. 2 Diluted alcohol, to make. . .fl.oz. 16 Extract the drugs by percolation or maceration. — Eclectic. Authority is also given for making this preparation by mixing 8 fluidounces of U. S. P. tincture of golden seal, 5 of U. S. P. tincture of lobelia and 3 fluidounces of diluted alcohol. Tincture of Green Soap. (Tincture Saponis Vieridis.) This is now known as liniment of soft soap, which see. Tincture of Green Soap, Compound. Green (soft) soap av.oz. 2^4 Oil of cade fl.dr. 2^ Alcohol, to make fl.oz. 16 Dissolve the soap in 12 fluidounces of alcohol, add the oil, and then enough alcohol to make the product measure 16 fluidounces, and filter. Tincture of Guaiac. I. Guaiac resin ("gum guaiac"), No. 40 powder av.oz. Z X A Alcohol, to make fl.oz. 16 Macerate the drug in a stoppered con- tainer, in a moderately warm place, with 12 fluidounces of alcohol, during 3 days, with frequent agitation ; then filter, and when the liquid has drained off, pour on enough alcohol to make 16 fluid- ounces of filtrate. — U. S. P. II. Homeopathic : This is one-half the strength of the U. S. P. tincture and may be made from the latter by mixing it with an equal volume of alcohol. Dilutions are to be made from this with dispensing alcohol. See Dilutions, Homeopathic. Tincture of Guaiac, Ammoniated. (Comp Tincture of Guaiac.) I. - Guaiac resin ("gum guaiac"), No. 40 powder av.oz. zVa Aromatic spirit of ammonia, to make fl.oz. 16 Macerate the guaiac, in a stoppered container, in a moderately warm place, with 12 fluidounces of the spirit, during 3 days, agitating frequently; then filter, and, when the liquid has drained off, pour on enough spirit to make 16 fluid- ounces of filtrate.— U. S. P. II. Guaiac resin, powder av.oz. zV\ Oil of nutmeg m. 24 Oil of lemon m. 16 Stronger ammonia water of the Brit. Pharm. (32^ p. c. by weight) fl.dr. g l / 2 Alcohol, to make fl.oz. 16 Mix the water with 13 fluidounces of alcohol, add the resin, set aside in a closed vessel for 48 hours, agitating fre- 478 STANDARD FORMULARY OF quently, filter, dissolve the oils in the filtrate, and pass enough alcohol through the filter to make the filtrate measure 16 fluidounces.— Brit. Pharm. Tincture of Guaiac, Aromatic. See Mixture, Cholera, Greenhow's. Tincture of Guaiac, Comp. (De-wees' Tincture of Guaiac — Alkaline Tincture of Guaiac.) Guaiac resin av.oz. 2. .gr. 85 Potassium carbonate gr. 45 Pimenta, moderately fire powder gr. 240 Pumice, fine powder av.oz. 1 Alcohol fl.oz. 7 Water fl.oz. 7 Diluted alcohol, to make. ..fl.oz. 16 Triturate the guaiac and potassium carbonate with the pimenta and the pumice, and afterwards gradually with the alcohol. Next add slowly 7 fluid- ounces of cold water and triturate the mixture thoroughly. Then filter, and pass enough diluted alcohol through the filter to make 16 fluidounces. Each fluidram represents 7^ gr. of guaiac resin.— N. F. and Eclectic modi- fied. Tincture of Hemlock Spruce. (Tinc- ture of Abies Canadensis or Pinus Canadensis.) Fresh drug (bark and buds) containing solids gr. 730 (plant moisture, av.oz. 3.9) Alcohol fl.oz. 13^4 — Homeopathic. This is intended to make 16 fluid- ounces. This is a ix- tincture. See Tinctures, Homeopathic, for method of prepara- tion. Dilutions are made with dispensing alcohol. See Dilutions, Homeopathic. Tincture of Henbane. (Tincture of Hyoscyamus.) Henbane herb, No. 60 pow- der (containing not less than o.c8 rer cent, of my- driatic alkaloids) av.oz. 1% Diluted alcohol, to make. . . .fl.oz. 16 Prepare like tincture of belladonna leaves. The product, when assayed, should contain 0.005 gm. of alkaloids of hyoscy- amus. — U. S. P. The preparation of the Brit. Pharm. is of the same strength, but is not assayed. Tincture of Hips, Kademacher's. (Tinctura Cynosbati — Tincture of Bedeguar.) Rose hips, fresh, cut fine, .av.oz. 2 Alcohol fl.oz. 11H Macerate the hips with the alcohol for 7 days, agitating frequently, express, and filter. The filtrate should weigh 10 av.ounces. — H. Tincture, Homeopathic. Tinctures (or alcoholic solutions of solids and semi-solids) of homeopathic pharmacy are made from a variety of substances which are wholly or par- tially soluble in alcohol. Such sub- stances comprise all plants and parts of plants, such as barks, roots, woods, fruits and seeds, resins, gums, and bal- sams. This list should also include min- erals and chemicals which dissolve more readily in alcohol than in water. Substances such as phosphorus, and also volatile salts, are better prepared as solutions (tinctures, as they are also called by homeopathists), than as tritu- rations, in the making of which they are volatilized. Such solutions are to be often freshly prepared. Most of the tinctures of homeopathic pharmacy are made from fresh plant parts and hence the method of prepara- tion deserves especial treatment. All fresh plant parts contain water, which varies in amount, and in order to secure uniformity of product, the dry crude drug is taken as the starting point from whence to calculate the strength of the tincture. Hence the first thing to do is to calculate the proportion of moisture taking a small quantity of the fresh plant part, weighing it, then drying it by gentle heat on a water bath until there is no further loss of weight, and weighing again. The difference between the weight of the fresh drug and that of the dry drug is the weight of the PHARMACEUTICAL PREPARATIONS. 479 water contained in the fresh drug, and for this allowance must be made in the preparation of the menstruum. The finished tincture is to contain in every 10 parts an amount of fresh drug equiv- alent to i part of dry drug. In giving the formula for homeopathic tinctures, the amount of moisture or water which should be present is stated. If more is present, deduct the excess present from the water directed in the menstruum. If this cannot be done (because of use of strong alcohol, or for other reasons), the drug must be cautiously dried until it is reduced to the required weight. If the drug weighs less than the required weight, add enough water to bring it up to the re- quired amount. It will be observed, therefore, that the finished tincture con- tains alcohol with the proportion of water used with it in the menstrum as well as with the water present in the plant substance. To illustrate the method of making of tinctures, the following formula is given : Fresh drug containing sol- ids gm. ioo (plant moisture, cc. 185) Distilled water cc. 200 Alcohol cc. 650 To make 1000 cc. This means that if the drug used for 1000 cc. of tincture were dried, it would weigh 100 gm. The water present in the drug should weigh 185 gm. ; if it is more the drug should be dried some- what or proportionately less water should be used in the menstruum; if it is less, sufficient water should be added to the drug to bring it up to this amount. - This formula translated into equiva- lent ordinary terms is as follows : Fresh drug containing solids.gr. 730 (plant moisture, av.oz. 3) Distilled water fl.oz. 2> l A Alcohol fl.oz. ioj^ To make 16 fluidounces.. These tinctures are made by macera- tion or by percolation of the drug with the menstruum. Gummy or viscid sub- stances, or such as are not readily pene- trated by alcohol, are best extracted by maceration. If the drug can be finely sliced or bruised to pulp before adding menstruum, this should be done; other- wise it may be used whole. The drug and menstruum should be placed to- gether in a well-closed jar and macer- ated for a period varying from 2 to 4 weeks, according to the nature of the drug. Then decant the clear liquid and express the residue. The product should measure the total amount indicated in the formula. Sometimes it may be advantageous to pour on only one-half of the men- struum, to macerate for some time, ex- press as before, triturate the residue with twice its weight of powdered glass, and to complete the extraction by per- colation. As a rule, maceration is employed in the extraction of fresh drugs because of the difficulty of extracting them by per- colation. If the method of percolation is used, the drug should be reduced to a pulp in a mincing machine (meat chopper). The drug is then to be packed in a suitably-sized percolator in thin lay- ers with alternating layers of moderate- ly fine glass or fine white sand, then adding menstruum to saturate the drug, covering the percolator closely, macera- ting for 24 hours or longer, according to the nature of the drug, then allowing the percolate to drop at the rate of 10 to 30 drops per minute, and continuing the addition of menstruum (which should be added frequently so as to keep the drug covered) until the re- quired amount of tincture is obtained. In making a tincture by percolation, a certain required amount of moisture must be present in the drug exactly as when making a tincture by maceration. If more is present, less water must be used in the menstruum or a portion of it must be evaporated ; if less,«some wa- ter must be added to the drug. Tinctures of dry drugs are to be made according to the above method of per- 480 STANDARD FORMULARY OF eolation, but the regular U. S. P. method may be substituted for it, as it is not in- ferior and is more convenient. Distilled water only should be used for these preparations. Homeopathic tinctures are now usu- ally made of the strength of the first decimal dilution (ix or I in 10). In making the dilutions, the diluent or ve- hicle is described under each tincture. For method of making the dilutions, method of naming them, etc., see Dilu- tions, Homeopathic. Tincture of Hops. (Tinctura Humuli or Lupuli.) I. Hops, well dried, No. 20 powder av.oz. 3^4 Diluted alcohol, to make. . . .fl.oz. 16 Moisten the drug with 6 fluidounces of diluted alcohol, macerate for 24 hours, then pack firmly in a cylindrical percolator, and gradually pour diluted alcohol upon it until 16 fluidounces of percolate are obtained. — N. F. II. Hops av.oz. 3% Alcohol, water, each, to make fl.oz. 16 Mix 7 volumes of alcohol with 4 of water, and extract the drug with this menstruum by maceration for 7 days, agitating occasionally, expressing and fil- tering. — Brit. Pharm. Tincture of Horseradish. (Tincture of Armoracia or Cochlearia.) I. Fresh drug (root) containing solids gr." 730 (plant moisture, av.oz. 5) Distilled water fl.dr. 13 Alcohol fl.oz. 10^4 — Homeopathic. This is intended to make 16 fluid- ounces. See Tinctures, Homeopathic, for method of preparation. This makes a ix tincture from which 2x dilution is to be* made by mixing 1 volume of tincture, 4 of distilled water, and 5 of alcohol ; 3x and higher are to be made with dispensing alcohol. See Dilutions, Homeopathic. II. Horseradish root, freshly grated av.oz. 5 Alcohol av.oz. 4 Diluted alcohol sufficient Macerate the drug with the alcohol for 8 days, agitating twice daily, then transfer to a percolator, allow the liquid to drain, and pass enough diluted alcohol through the drug to make the total per- colate weigh 10 av.ounces. — Eclectic. Tincture of Ignatia. (Tincture of St. Ignatius' Bean.) Ignatia, No. 60 powder av.oz. 1 Alcohol, water, each sufficient Mix alcohol and water in the propor- tion of 8 parts by weight of the former to 1 part of the latter. Moisten the drug with 1 fluidounce of the men- struum, and macerate for 24 hours ; then pack it firmly in a cylindrical per- colator, and gradually pour menstruum upon it, until the drug is exhausted. Reserve the first 9 av.ounces, evaporate the remainder to 1 av. ounce, and mix with the reserved portion. Of this tinc- ture, take any convenient quantity, and, by means of a water bath, evaporate it to dryness. Weigh the resulting extract, and from its weight calculate the quan- tity of extract contained in the 100 parts of tincture obtained ; then dissolve the dried extract in the remainder of the tincture, and add enough of the above menstruum to make the product weigh so many parts that each 100 parts by weight of tincture shall contain 1 part of dry extract. Lastly, mix thoroughly, and filter through paper. Tincture of ignatia thus prepared rep- resents about 10 parts by weight of ig- natia in 100 parts. — N. F. Appendix and U. S. P. 1880. II. Dry drug gr. 730 Distilled water fl.oz. 2^2 Alcohol fl.oz. 14 — Homeopathic. This is intended to make 16 fluid- ounces. See Tinctures, Homeopathic, for method of preparation. PHARMACEUTICAL PREPARATIONS. 481 This makes a ix tincture. Dilutions are to be made from this with dispensing alcohol. See Dilutions, Homeopathic. Tincture of Iodin. I. Iodin gr. 510 Potassium iodid .gr. 365 Distilled water fl.dr. 6 Alcohol, to make fl.oz. 16 Dissolve the potassium iodide in the distilled water, contained in a 16 ounce bottle, add the iodine and shake until dissolved. Then add sufficient alcohol to make 16 fluid ounces. — U. S. P. This formula differs from the U. S. P. 1900, which did not contain water, the iodin and potassium iodid being trit- urated together in a mortar. This, as well as the 1900 formula, dif- fers from that of previous editions, in containing potassium iodid and is there- fore similar to the tincture of iodin of the B. P. and the compound tincture of iodin of U. S. P. 1870. The iodin and potassium iodid might be dissolved in the alcohol, but solution of the potassium iodid in the water has- tens the process. II. Iodin gr. 183 Potassium iodid gr. 183 Distilled water fl.dr. z l A Alcohol, to make fl.oz. 16 Mix the iodin, potassium iodid and water in a bottle, and when dissolved add the alcohol. — Brit. Pharm. This differs from the other tinctures of iodin here given in being much weaker. It is more like the compound tincture of iodin of the U. S. P. 1870, which see. III. Iodin, triturated gr. 605 Alcohol fl.oz. 16 Mix in a glass-stoppered bottle, and agitate occasionally, without warming, until the iodin is dissolved. — Germ. Pharm. IV. Iodin gr. 730 Alcohol, to make fl.oz. 16 Dissolve by agitation, trituration, or other suitable means. — Homeopathic. This is a ix tincture from which dilu- tions are to be made with alcohol. See Dilutions, Homeopathic. Tincture of Iodin, Churchill's. Iodin gr. 300 Potassium iodid gr. 60 Water fl.oz. 1 Alcohol, to make fl.oz. 4 Dissolve the potassium iodid in the water, then add the iodin, and lastly, enough alcohol to make the tincture, when completed, measure 4 fluidounces. — N. F. This preparation should not be con- founded with Solution of Iodin, Caustic, nor with Tincture of Iodin, Compound. Tincture of Iodin, Compound. Iodin gr. 240 Potassium iodid gr. 480 Alcohol fl.oz. 16 Mix and dissolve. — U. S. P. 1870. This must not be confused with Solu- tion of Iodin, Compound, of the present U. S. P. It is also very similar to tinc- ture of iodin of the Brit. Pharm. See Tincture of Iodin, No. II. Tincture of Iodin, Decolorized or Colorless. I. Iodin gr. 600 Sodium thiosulfate gr. 600 Water fl.oz. V/ 2 Stronger ammonia water (U. S. P.) fl.oz. 1 Alcohol, to make fl.oz. 16 Digest the iodin, sodium thiosulfate, and water, at a gentle heat, until a per- fect solution, of a dark reddish-brown color, is produced. Then add 2 fluid- ounces of alcohol, and afterwards the stronger ammonia water. Shake a few minutes until no more bubbles of gas escape, and the liquid has become color- less, with a whitish precipitate (of sul- fur) suspended in it. Cool it, if neces- sary, and add enough alcohol to make 16 fluidounces. Place the bottle con- taining it in a refrigerator for a few hours, or longer if convenient then Al- ter, in a covered funnel, and preserve the liquid for use. 482 STANDARD FORMULARY OF On prolonged- standing a crystalline precipitate, of sodium tetrathionate, will usually form in the liquid. This may be removed by filtration. — N. F. This preparation is almost identical with the preparation of the same name recognized by the supplement to the Germ. Pharm. ; see No. II. The stronger ammonia water should be of the strength known as 28 per cent. The above is somewhat stronger in iodin than the official tincture of iodin, the latter containing 510 grains of iodin to the pint. II. Iodin gr. 610 Sodium hyposulfite gr. 610 Distilled water fl.dr. 11 Ammonia water, 10 p. c. . . .fl.oz. 2^4 Alcohol fl.oz. 12 Mix the first three ingredients in a bottle, set this in cold water and agitate frequently until solution is effected. To this add gradually, with agitation, the ammonia water, and after several min- utes add the alcohol. — Germ. Pharm., Supplement. III. The N. F. preparation contains the iodin in the form of iodids of am- monium and sodium. Sieker has devised this formula for the expeditious prep- aration of a product practically the same as furnished by the N. F. formula : Sodium iodid gr. 360 Ammonium iodid gr. 345 Ammonia water, 10 p. c m. 80 Distilled water fl.oz. 2 T /4 Alcohol, to make fl.oz. 16 The product will be colorless and quite permanent, provided pure alcohol has been employed. IV. Iodin gr. 208 Stronger ammonia water. ..sufficient Alcohol, to make fl.oz. 16 Dissolve the iodin in 4^2 fluidounces of alcohol by the aid of agitation and a gentle heat. When cold, add the am- monia water (using 1 fluidounce of the stronger water of the Brit. Pharm.— 32^2 p. c. — or 9 T /2 fluidrams of the stronger water of the U. S. P.— 28 p. c), keep the mixture in a warm place until de- colorized, after which add the remainder of the alcohol. — Brit. Form. Tinctrre of Iodin, Ethereal, Magen- die's. Iodin gr. 32 Ether fl.oz. 1 Tincture of Iodoform. Iodoform gr. 600 Oil of fennel fl.dr. 4 Alcohol fl.oz. 7 Ether fl.oz. 8 Dissolve the iodoform in the ether, the oil in the alcohol, and mix the solu- tions. — Eclectic. Tincture of Ipecac. Dry drug (root) gr. 730 Distilled water fl.oz. zV\ Alcohol fl.oz. 13 J4 — Homeopathic. This is intended to make 16 fluid- ounces. See Tinctures, Homeopathic, for method of preparation. This makes a ix tincture. Dilutions are to be made from this with dispensing alcohol. See Dilutions, Homeopathic. Tincture of Ipecac and Opium. (Dover's Tincture.) Tinct. of deodorized opium.. fl.oz. 16 Fluid extract of ipecac fl.dr. 13 Diluted alcohol sufficient Evaporate the tincture in a tared dish on a water bath until it weighs 13 av.- ounces. When cold add the fluid ex- tract, filter the mixture, and through the filter add enough diluted alcohol to make 16 fluid ounces of product. — N. F. Tincture of Iron Acetate, Rade- macher's. I. Iron (ferrous) sulfate, purc.gr. 656 Lead acetate, pure gr. 684 Diluted acetic acid fl.oz. 6 Distilled water fl.oz. 3 Alcohol fl.oz. 6 Triturate the two salts together to a pasty mass, introduce this into an iron vessel, add the water and acid, heat to boiling, allow to cool, transfer to a large flask, add the alcohol, set the flask, loosely stoppered, aside for several months, agitating occasionally until the PHARMACEUTICAL PREPARATIONS. 483 liquid has acquired a light red tint, and finally filter.— H. A more expeditious process for ma- king this preparation would be by the use of solution of. iron tersulfate, as fol- lows (process of Bosetti in D.) : Solution of iron tersulfate, U. S. P fl.oz. 2 X / A Distilled water fl.oz. i% Lead acetate, pure, crystal, .av.oz. iJ4 Diluted acetic acid fl.oz. 5 Alcohol fl.oz. 434 Dissolve the lead acetate in the acid, filter the solution, add the iron solution previously mixed with the water, then gradually add the alcohol, set aside for one or two weeks and decant the clear liquid, which is the finished product. This makes a preparation having an odor not like that of the original, but its therapeutic value is undoubtedly the same. II. Solution of iron acetate fl.oz. 6^4 Alcohol fl.oz. sVa Acetic ether fl.oz. 3 l / 2 Mix the alcohol and ether, and gradu- ally add the solution, taking care that the mixture remains cool. — U. S. P. 1880. Keep the product in glass-stoppered bottles, in a cool, dark place. This resembles the tincture of iron acetate, ethereal, of the Germ. Pharrri., which see. III. Solution of iron acetate fl.oz. 4 Acetic acid fl.dr. Y4 Alcohol fl.oz. 4 Distilled water fl.oz. 7^ —Brit. Pharm. 1885. Tincture of Iron Acetate, Ethereal. (Klaproth's Tincture of Iron.) Solution of iron acetate, U. S. P fl.oz. 7Y 2 Distilled water fl.oz. 5 Alcohol fl.oz. 2 Acetic ether fl.dr. 15 — Germ. Pharm. (3rd edition). Keep protected from light in a cool place. See also Tincture of Iron Acetate. No. II, for a similar article. 31 Tincture of Iron (Ferric) Chlorid. (Tincture of Iron Perchlorid, Sesquichlorid or Muriate — Chlor- inated Tincture of Iron — "Tinc- ture of Iron" — Steel Drops.) I. Solution of ferric chlorid. . .fl.oz. $ x / 2 Alcohol, to make fl.oz. 16 Mix, allow to stand in a closely-cov- ered vessel, protected from light, at least 3 months, then transfer to glass-stop- pered bottles, and keep protected from light. This is described as a hydro-alcoholic solution of ferric chlorid, containing about 13.28 per cent, by weight of the anhydrous salt (ferric chlorid), corre- sponding to about 4.6 per cent, of me- tallic iron.— U. S. P. The preparation of the Brit. Pharm. is made from 1 volume each of strong solution of iron chlorid (Brit. Pharm.) and alcohol and 2 of water. The mix- ture is not to be put aside before use, as directed by the U. S. P. It contains about 15.4 per cent, by weight of the anhydrous salt, corresponding to about 5.3 p. c. of metallic iron. II. Solution of iron chlorid, U. S. P fl.oz. 4^ Alcohol, to make fl.oz. 16 — Homeopathic. This makes a ix tincture from which 2x and higher dilutions may be made by addition of dispensing alcohol. See Dilutions, Homeopathic, for method of preparation. Tincture of Iron Chlorid, Ethereal. (BestuchefFs Nervine Tincture — Lamotte's Golden Drops.) Solution of iron chlorid. .. .fl.dr. y l / 2 Stronger ether fl.oz. 4 Alcohol, to make fl.oz. 16 Mix the solution of iron chlorid with 10 fluidounces of alcohol, add the ether, and lastly, enough alcohol to make 16 fluidounces. Introduce the tincture into bottles made of white (flint) glass, which should not be entirely filled. Cork them tightly and expose them to the rays of the sun, until the tincture has been completely decolorized. Then re- 484 STANDARD FORMULARY OF move the bottles to a shady place, and open them occasionally, until the con- tents have again assumed a yellow color. Lastly, transfer the tincture to bottles, which should be well stoppered and kept in a cool and dark place. Each fluidram represents about J4 gr. of metallic iron. This preparation is practically identi- cal with that which is official in the Germ. Pharm. — N. F. Tincture of Iron Chlorid, Toluenated. (Loeffler's Solution.) Solution of ferric chlorid. . .fl. dr. sVa Toluene fl.dr. 6 Absolute alcohol, to make., fl.oz. 16 Keep in a dark colored bottle. — Cine. Acad. Pharm. This is used as a local application for faucial diphtheria. See also Tincture of Iron Chlorid, Toluenated, with Menthol. Tincture of Iron Chlorid, Toluenated, with Menthol. (Loeffler's Solu- tion with Menthol.) Solution of ferric chlorid. .fl.dr. 5*4 Menthol gr. 730 Toluene fl.oz. 4^ Absolute alcohol, to make, .fl.oz. 16 Keep in a dark colored bottle. — Cine. Acad. Pharm. It is used as a local application for faucial diphtheria. See also Tincture of Iron Chlorid, Toluenated. Tincture of Iron Citro-Cchlorid. (Tasteless Tincture of Chlorid of Iron — Tasteless or Creuse's Tinc- ture of Iron.) Solution of iron chlorid. .. .fl.oz. S J A Sodium citrate av.oz. 7 Alcohol fl.oz. 2^/2 Water, to make fl.oz. 16 Mix the solution of iron chlorid with 2}/ 2 fluidounces of water, and dissolve in this mixture the sodium citrate with the aid of a gentle he?t Then add the alcohol, and when the solution has be- come cold, make up the volume with water to 16 fluidounces. Set the prod- uct aside in a cold place for a few days, if convenient, so that the excess of sa- line matter may separate. Then filter, and pass enough cold water through the filter to restore the original volume. Each fluidram contains an amount of iron equivalent to about 7H gr- of dry iron (ferric) chlorid. This preparation is practically identi- cal in the strength of iron, but not in the quantity of alcohol, with the official tincture of iron chlorid. — N. F. This preparation may be made with citric acid and sodium bicarbonate in- stead of sodium citrate as follows : Solution of iron chlorid. .. .fl.oz. 5^2 Sodium bicarbonate av.oz. 6 Citric acid av.oz. 5 Alcohol fl.oz. 2V2 Distilled water, to make. .. .fl.oz. 16 Dissolve the citric acid in a capacious vessel in 7 fluidounces of distilled water by the aid of heat, and add the sodium bicarbonate gradually and with occa- sional stirring. When all has been added and the bicarbonate is all or nearly all dissolved, apply a gentle heat until all is dissolved and there is no further disengagement of gas. To this solution add the solution of iron chlorid and the alcohol and then enough dis- tilled water to make 16 fluidounces. Al- low the mixture to stand a few days if convenient, to allow the saline matter to deposit, filter, and add through the filter enough distilled water to make the filtrate measure 16 fluidounces. Sodium carbonate is used sometimes instead of the bicarbonate, but the latter should be preferred because more read- ily obtained pure. Tincture of Iron, Compound. Tincture of ferrated extract of apples fl.oz. 8 Vinous tincture of rhubarb, .fl.oz. 8 Tincture of nux vomica fl.oz. 1 Tincture of Iron Pomated. See Tincture of Ferrated Extract of Apples. PHARMACEUTICAL PREPARATIONS. 485 Tincture of Jaborandi. (Tincture of Pilocarpus.) I. Jaborandi, No. 40 powder. av.oz. 3% Diluted alcohol, to make. . . .fl.oz. 16 Extract the drug by percolation. — Brit. Pharm. II. Dry drug (leaves) gr. 730 Alcohol, to make fl.oz. 16 — Homeopathic. See Tinctures, Homeopathic, for method of preparation. This makes a ix tincture. Dilutions are made from this with dispensing alcohol. See Dilutions, Homeopathic. Tincture of Jalap. I. Jalap, fine powder av.oz. 3^ Alcohol, water, each to make fl.oz. 16 Mix 2 volumes of alcohol with 1 of water, and percolate the jalap with this mixture, in the usual manner, until 16 fluidounces of tincture are obtained. — N. F. II. Jalap, No. 40 powder av.oz. 4 Alcohol, water, each sufficient Mix the alcohol and water in the pro- portion of 3 volumes of the former to 1 of the latter, moisten the drug with 2 fluidounces of this menstruum, pack in a percolator, gradually add more of the menstruum until 11^ fluidounces of per- colate have been obtained, express the marc, mix the expressed liquid with the percolate, set aside for 24 hours, and filter.— Brit. Pharm. Determine the amount of resin in the tincture and dilute the latter with the same menstruum so that 100 cc. of the diluted tincture contains 1.5 grams of resin. III. Jalap, coarse powder av.oz. 3^ Water fl.oz. 4 x / 2 Alcohol fl.oz. n^2 Mix, macerate for 10 days, agitating occasionally, express, and filter. — Codex. Tincture of Jalap, Compound. (Tinc- tura Purgans.) I. Jalap, fine powder av.OZ. 2 Scammony, fowder av.OZ. 14 Alcohol, water, each to make fl.oz. 14^ Mix 2 volumes of alcohol with 1 of water and use as a menstruum. Mix the powders with half their weight of sand; moisten the mixture with a sufficient quantity of the menstruum, pack it in a percolator, and percolate it with the menstruum, in the usual manner, until 14^ fluidounces of tincture are ob- tained.— N. F. II. The French preparation is slightly different as follows (from the Codex) : Jalap av.oz. 1 J4 Turpeth root gr. 70 Scammony gr. 140 Water fl.oz. 5 Alcohol fl.oz. 12 Mix, macerate for 10 days, agitating occasionally, express, and filter. Tincture of Jamaica Dogwood. (Tincture of Piscidia.) Dry drug (root bark) gr. 73® Distilled water fl.oz. 3*4 Alcohol fl.oz. 13^4 — Homeopathic. This is intended to make 16 fluid- ounces. See Tinctures, Homeopathic, for method of preparation. This makes a ix tincture, from which dilutions are to be made with dispensing alcohol. See Dilutions, Homeopathic. Tincture of Kino. I. Kino av.oz. UA Boiling water fl.oz. 8 Alcohol, to make fl.oz. 16 Place the kino in a capacious flask and pour on 8 fl. ozs. boiling water. Agitate the mixture thoroughly and heat it on a water bath for about one hour; allow the flask and contents to cool, and re- store the original weight by the addition of sufficient recently boiled water. Then add the alcohol, mix well. Stopper the flask, set it aside in a cool place for twenty- four hours and then decant the 486 STANDARD FORMULARY OF mixture through cheesecloth. Preserve it in small bottles, tightly corked, in a cool place. — U. S. P. It is believed that, in the present prep- aration, the tendency to gelatinize is largely eliminated. In any case this is largely due to the introduction of air, hence the directions to keep in small bottles, so that the loss from this cause may be slight. The heating on the water bath is for the purpose of destroying the oxydases which are believed to cause the subse- quent gelatinization of the tincture. II. The Brit. Pharm. preparation dif- fers from that of the U. S. P. only in using 4 fluidounces of water instead of z l A, in mixing the glycerin and water with 8 fluidounces of alcohol, instead of 10^4, in macerating for 12 hours instead of 24, and in straining through cotton instead of filtering. III. This is also called Tincture of Australian Red Gum : Drug gr. 730 Alcohol, to make fl.oz. 16* — Homeopathic. See Tinctures, Homeopathic, for method of preparation. This makes a ix tincture, from which dilutions are to be made with dispensing alcohol. The Australian or Botany Bay kino is the kind recognized by the homeopathic pharmacopeia. Tincture of Kino, Compound. Tincture of kino fl.oz. 3 Tincture of opium fl.oz. i l / 2 Spirit of camphor fl.oz. 65 Oil of clove m. 11 Cochineal, powder gr. 60 Aromatic spirit of ammonia. fl. dr. 1 Diluted alcohol, to make. ...fl.oz. 16 Triturate the cochineal with the aro- matic spirit of ammonia, and gradually add 11 fluidounces of diluted alcohol. Then add the two tinctures, the spirit of camphor, and the oil, and filter the mix- ture through paper. Lastly, pass enough diluted alcohol through the filter to make 16 fluidounces. — N. F. Each fluidram represents about Yz gr. each of kino and opium. This preparation may be made directly from the drugs as follows : Kino gr. 72 Opium, powder gr. 72 Clove, coarse powder gr. 72 Camphor gr. 50 Cochineal, powder •. .gr. 64 Aromatic spirit of ammonia. fl. dr. 1 Alcohol, to make fl.oz. 16 Mix, macerate for 3 or 4 days, agitat- ing frequently, filter, and through the filter add alcohol enough to make 16 fluidounces of filtrate. Tincture of Lactucarium. Lactucarium (German or English preferred) av.oz. 8 J /i Glycerin fl.oz. 4 Water, alcohol, purified pe- troleum benzin, and di- luted alcohol, each sufficient Beat the lacturcarium in an iron mor- tar, with clean sand, to a coarse powder, and put into a suitable bottle ; add 32 fluidounces of benzin, cork the bottle tightly, and set it aside for 48 hours, frequently agitating the mixture. Pour the mixture on a double filter, and allow it to drain. Wash the residue by gradu- ally adding 24 fluidounces of benzin. Al- low the lacturcarium to dry by exposing it to a current of air. When it is dry, and free from the odor of benzin, reduce it to powder, using more sand, if neces- sary, and pack it moderately in a conical percolator. Mix the glycerin with 2> X A fluidounces of water and 8 fluidounces of alcohol, and moisten the drug with 8 fluidounces of this mixture. When the liquid begins to drop from the percola- tor, close the lower orifice, and having closely covered the percolator, macerate for 24 hours. Then allow percolation to proceed very slowly, gradually add- in, first, the remainder of the men- struum, and then diluted alcohol, until the drug is exhausted. Reserve the first 12 fluidounces of percolate, evaporate the remainder on a water bath at a temperature not exceeding 70 deg. C. to 4 fluidounces, mix this with the re- PHARMACEUTICAL PREPARATIONS. -±87 served portion, filter, and through the filter add diluted alcohol, if necessary, to make the filtrate measure 16 fluid- ounces. — U. S. P. Tincture Larkspur. Larkspur seed oz. V/z Alcohol, q. s. Macerate six hours and percolate in the usual way to 16 fluid ounces. — N. F. Tincture of Lavender, Comp. (Com- pound Spirit of Lavender, U. S. P. 1870 — Lavender Drops.) I. Saigon cinnamon, coarse powder av.oz. I Nutmeg av.oz. y 2 Red saunders av.oz. x / 2 Clove av.oz. \/\ Oil of lavender flowers fl.dr. 3 Oil of rosemary m. 45 Alcohol, water, each, to make fl.oz. 48 Dissolve the oils in 36 fluidounces of alcohol and add 12 fluidounces of water. Reduce the four drugs to No. 50 pow- c*:r, and macerate this with the previ- ( usly prepared liquid for 3 days, agi- tating occasionally. Then filter, and when the liquid has drained off com- pletely, pass enough of a mixture of 3 volumes of alcohol and 1 of water through the residue on the filter to make 48 fluidounces of filtrate. — U. S. P. Mace, powder gr. 45 Red saunders, powder av.oz. J /2 Oil of lavender flowers m. 45 Oil of anise m. 25 Brandy fl.oz. 1 Jamaica rum fl.oz. 32 Mix, macerate for 14 days, agitating occasionally, express, and filter. — Ec- lectic. This is claimed by Eclectics to be more agreeable than the U. S. P. prep- aration. III. Ceylon cinnamon, bruised gr. 180 Nutmeg, bruised gr. 180 Red saunders gr. 360 Oil of lavender flowers m. no Oil of rosemary m. 12 Alcohol fl.oz. 48 Mix the solids with the alcohol, mac- crate for 7 days, agitating occasoinally, strain with expression, filter, and add the oils. — Brit. Pharm. Tincture of Lemon Peel. I. Lemon peel av.oz. 8^4 Alcohol, to make fl.oz. 16 The lemon peel should be from the fresh fruit, and should be in thin shav- ings and cut into narrow shreds. Mac- erate it in a stoppered, wide-mouthed container, in a moderately warm place, with 16 fluidounces of alcohol during 48 hours, r agitating frequently; then filter through absorbent cotton and when the liquid has drained off completely, gradu- ally pour on alcohol enough to make 16 fluidounces of tincture, and filter the whole.— U. S. P. This is used to make syrups. II. Lemon peel, fresh, cut small , av.oz. 4^ Alcohol fl.oz. 16 Macerate together for 7 days, agitat- ing occasionally, strain with expression, and filter. — Brit. Pharm. Tincture of Linden. (Tincture of Tilia.) Fresh drug (flowers), con- taining solids gr. 730 (plant moisture, .av.oz. 5) Alcohol fl.oz. ii^4 — Homeopathic. This is intended to make 16 fluid- ounces. See Tinctures, Homeopathic, for method of preparation. This makes a ix tincture. Dilutions: 2x is to be made from 1 volume of tincture, 2 of distilled water, and 7 of alcohol; 3x and higher are to be made with dispensing alcohol. See Dilutions, Homeopathic. Tincture of Lobelia. I. Lobelia herb, No. 50 pow- der av.oz. \¥\ Diluted alcohol, to make.. fl.oz. 16 — U. S. P. Prepare like tincture of cantharides, using diluted alcoha' as a menstruum. 488 STANDARD FORMULARY OF II. Lobelia herb, cut moder- ately fine av.oz. i l / 2 Water fl.oz. z l / 2 Alcohol fl.oz. 13 Mix, macerate for 7 days, agitating occasionally, strain with expression, and filter.— Germ. Pharm. III. Lobelia, No. 40 powder. . .av.oz. 2 Alcohol, water, to make fl.oz. 16 Extract the drug by percolation, using as a menstruum a mixture of 9 volumes of alcohol and 5 of water. — Brit. Form. IV. Fresh drug (whole plant of Lobelia inflata) _ gr. 700 (plant moisture, .av.oz. 5) Alcohol fl.oz. 11& — Homeopathic. This is intended to make 16 fluid- ounces. See Tinctures, Homeopathic, for method of preparation. This is a ix tincture. Dilutions : 2x are to be made from 1 volume of tinc- ture, 2 of distilled water, and 7 of alco- hol; 3x and higher are to be made with dispensing alcohol. See Dilutions, Homeopathic. V. Thomsonian : Lobelia herb in any stage of its growth but before the leaves have become yel- low, bruise, and mix with fourth-proof spirit (5 volumes of alcohol and 3 of water), macerate, and then express. Thomson sometimes used good vine- gar or pepper sauce instead of the spirit. Tincture of Lobelia, Ethereal. Lobelia herb, No. 40 pow- der av.oz. zVa Spirit of ether, to make. .. .fl.oz. 16 Extract the drug by percolation. — Brit. Pharm. The preparation of the Brit. Pharm. 1885 was made with 2 av.ounces of drug to the pint. See also Tinctures, Ethereal. Tincture of Lobelia and Capsicum, Compound. (Antispasmodic Tinc- ture.) Lobelia herb av.oz. 1 Capsicum av.oz. 1 Skunk cabbage av.oz. 1 Diluted alcohol, to make... fl.oz. 16 Mix the drugs in moderately fine pow- der and extract by percolation or macer- ation. — Eclectic. Tincture of Lobelia, Comp. (King's Expectorant Tincture.) Lobelia herb av.oz. \i Blood-root av.oz. % Skunk cabbage av.oz. % Canada snake root av.oz. ^ Pleurisy root av.oz. *4 Alcohol, water, each, to make fl.oz. 16 Mix the drugs and reduce to fine pow- der; mix the alcohol and water in the proportion of 3 volumes of the former to 1 of the latter, and extract the mixed drugs by percolation or maceration. Vinegar (or diluted acetic acid) may be used instead of the water. — Eclectic. Tincture of Lycopodium. (Tincture of Club Moss.) Lycopodium, previously tri- turated many hours, to break the spores gr. 183 Alcohol, to make fl.oz. 4 — Homeopathic. This makes a ix tincture. Dilutions are to be made with dispensing alcohol. See Dilutions, Homeopathic. To obtain satisfactory preparations of lycopodium, much time and labor must be expended to triturate the spores, that the oil contained therein may be ex- tracted ; this can be most effectually accomplished by triturating with sugar of milk. The trituration is therefore the most reliable preparation of lycopo- dium. Tincture of Magnesium Chlorid. Magnesium chlorid, dry or anhydrous gr. 46 Dispensing alcohol fl.oz. 1 — Homeopathic. This forms a ix tincture, from which dilutions are to be made with dispensing alcohol. See Dilutions, Homeopathic. PHARMACEUTICAL PREPARATIONS. ±89 Tincture of Mary Thistle. (Tincture of St. Mary's Thistle or Carduus Marianus — Tinctura Cardui Ma- rise — Stechkoerner Tinktur.) I. Rademacher's (in H. and D.) : Carduus Marianus fruit, whole av.oz. 10 Alcohol fl.oz. li T A Distilled water fl.oz. gY 2 Macerate for 8 days, agitating occa- sionally, then filter. The fruit is extracted in the whole condition, owing to its highly mucila- ginous character. II. A homeopathic tincture is made as follows : Whole ripe seed part l Diluted alcohol parts 2 Mix, let stand in a well-stoppered bot- tle in a cool place for 8 days, agitate twice daily, and filter. All parts are parts by weight. It will be observed that the two prep- arations are practically identical. Tincture of Matico. Matico, No. 40 powder. .. .av.oz. 1^2 Diluted alcohol, to make. . . .fl.oz. 14^ Moisten the drug with 13 fluidrams of diluted alcohol, macerate for 24 hours, pack firmly in a cylindrical per- colator, and pour on diluted alcohol until 14^2 fluidounces of percolate are obtained. Tincture of May-Apple. (Tincture of Mandrake or Podophyllum.) I. Resin of podophyllum gr. 256 Alcohol, enough to make. . .fl.oz. 16 Add the resin to 143/2 fluidounces of alcohol, set aside for 24 hours, occa- sionally agitating, filter, and add enough alcohol through the filter to make the filtrate measure 16 fluidounces. — Brit. Pharm. This contains twice the proportion of resin present in the preparation of the Brit. Pharm. 1885. II. Podophyllum, fine powder. av.oz. 3 Alcohol, to make fl.oz. 16 Extract the drug by percolation or maceration. — Eclectic. III. Fresh drug (root) contain- ing solids gr. 730 (plant moisture, .av.oz. sH) Alcohol fl.oz. 11 — Homeopathic. This is intended to make 16 fluid- ounces. See Tinctures, Homeopathic, for method of preparation. This makes a ix tincture. Dilutions : 2x is to be made from 1 volume ot tincture, 3 of distilled water, and 6 of alcohol. See Dilutions, Homeopathic. Tincture of Mercuric Chlorid. (Tine- ture of Mercurius Corrosivus.) Mercuric chlorid gr. 46 Alcohol fl.oz. 1 — Homeopathic. This is a ix tincture, from which di- lutions are made with dispensing alco- hol. See Dilutions, Homeopathic. Tinctures, Mother. The term "mother tinctures" was for- merly used in homeopathic works but has been abandoned in the later works of authority in favor of the simple term "tinctures." Commercially, however, the term is still used and signifies the basic preparations, usually of crude drugs, from which the dilutions ("attenuations" or "potencies") are to be prepared. Di rections for preparing each tincture are given in this work in its proper alpha- betical place while the general direc- tions for this class of tinctures is given under Tinctures, homeopathic, which see. For preparing the dilutions, see Dilutions, Homeopathic. Tincture of Mugwort Root, Rade- macher's. (Tincture of Arte- misia.) Mugwort root, cut av.oz. 3 Alcohol fl.oz. 8*4 Water fl.oz. 7 Mix, digest for 3 days, express, and filter.— H. Tincture of Musk. (Tinctura Moschi.) I. Musk gr. 92 Alcohol fl.dr. 1454 Water fl.dr. 14V2 Diluted alcohol, to make ... fl.oz. 4 Triturate the musk with the water, h. 490 STANDARD FORMULARY OF little at a time, until a smooth mixture is obtained ; transfer this to a bottle and allow it to stand 24 hours; add the alcohol and macerate for 6 days, agi- tating occasionally Then filter through a plain paper filter, and when the liquid has drained off completely, pass enough diluted alcohol through the filter to make 4 fluidounces of filtrate.— U. S. P. The musk used for this preparation should be of first-class quality ; the num- erous inferior grades are useless for medicinal effect. II. Musk gr. 132 Distilled water fl.oz. 7Ya Alcohol fl-oz. S l A Triturate the musk with the water, add the alcohol.— Germ. Pharm. 3rd edi- tion. Tincture of (White) Mustard. (Tinc- ture of Sinapis Alba.) Drug (the fresh ripe seed).gr. 730 Alcohol, to make fl.oz. 16 — Homeopathic. See Tinctures, Homeopathic, for method of preparation. This makes a ix tincture, from which dilutions are to be made with dispensing alcohol. See Dilutions, Homeopathic. Tincture of Myrrh. I. Gum myrrh, moderately coarse' powder av.oz. S X A Alcohol, to make fl.oz. 16 Macerate the drug in a stoppered con- tainer, in a moderately warm place, dur- ing 3 days, agitating frequently; then filter through absorbent cotton, or a plain paper filter, and, when the liquid has drained off completely, pour on enough alcohol to make 16 fluidounces of filtrate.— U. S. P. II. The preparation of the Brit. Pharm. is of the same strength; the maceration is for 7 days. IV. Myrrh, coarse powder av.oz. 2 r / 2 Alcohol fl.oz. 14^ — Germ, and Austr. Pharms. Tincture of Myrrh, Compound. (Hot Drops.) Myrrh, moderately fine pow- der av.oz. 1 Capsicum, fine powder av.oz. l /i Alcohol, to make fl.oz. 16 — Eclectic. Prepare the tincture by percolation or maceration. This is a variation of the Thomsonian No. 6; see Tincture of Capsicum and Myrrh. Tinctures, Normal. The use of the term "normal" as ap- plied to tinctures is confined to Eclectic pharmacy, and it signifies that the prod- uct, the "normal tincture," represents the dry drug weight for weight. They may be prepared from fresh or from dry drugs or by the use of a greater or less proportion of alcohol in the men- struum, but the strength of the product is always based upon the drug in a dry condition. In the case of the tinctures prepared from dry drugs, the menstruum varies according to the nature of the drug, but in the case of the tinctures of fresh drugs, the drug is dried par- tially, if necessary, and alcohol and wa- ter added in such proportions that the product will contain 50 p. c. of alcohol. Good fluid extracts may always be dis- pensed in place of the corresponding "normal tinctures." Normal tinctures are designated by Eclectics for brevity's sake, as "tinc- tures — ." Tinctures one-half the strength of normal tinctures are called semi-normal — ; one-fifth as quinti- II normal one-tenth as deci-normal etc. Myrrh av.oz. 1^2 A.lcohol enougJi ta make. . .fl.oz. 16 — Eclectic (old formula). Tincture of Nutgall. (Tinctura Gal- la; or Gallarum— Tincture of Galls.) I. Nutgall, No. 40 powder av.oz. 354 Glycerin fl-dr. 13. Alcohol, to make fl-oz. 16 PHARMACEUTICAL PREPARATIONS. 491 Mix the glycerin with 14H fluidounces of alcohol. Introduce the drug, without moistening it, into a glass percolator, shaking down the powder evenly and compactly, and pour on enough of the menstruum to saturate it and leave a stratum above it. Allow percolation to proceed slowly, pouring on, first, the re- mainder of the menstruum, and then enough alcohol to make 16 fluidounces of percolate. — U. S. P. II. Nutgall, No. 12 powder. . . .av.oz. 3 Water fl.oz. 2>Y 2 Alcohol fl.oz. 13 Mix, macerate for 7 days, agitating occasionally, strain with expression, and filter. — Germ, and Austr. Pharms. Tincture of Nutmeg. (Tincture of Nux Moschata.) Dry drug (seed, coarse powder) gr. 730 Alcohol, to make fl.oz. 16 — Homeopathic. See Tinctures, Homeopathic, for meth- od of preparation. This makes a ix tincture. Dilutions are to be made with, dispensing alcohol. See Dilutions, Homeopathic. Tincture of Nux Vomica. (Tinctura Strychni — Tincture of Poison Nut — Tinctura Nucum Vomicar- um.) I. Extract of nux vomica (con- taining 5 p. c. of strych- nine) gr. 146 Alcohol, water, each, to make fl.oz. 16 Mix alcohol and water in the propor- tion of 3 volumes of the former to 1 of the latter, and in this mixture dissolve the extract, using enough of the liquid to make 16 fluidounces, and filter this in a well-covered funnel. — U. S. P. This tincture, when assayed, should contain 1 gm. of strychnine in 1000 cc. II. Rademacher's : Nux vomica, rasped or gra- ted av.oz. 3 Water fl.oz. 7 Alcohol fl.oz. &y 4 Mix, digest for 3 days, express, and filter.— H. Inasmuch as this is of approximately the same relative strength as the U. S. P. preparation, and, as the latter is a superior preparation, it should always be dispensed for the Rademacher prep- aration. III. Fluid extract of nux vomica, Brit. Pharm fl.oz. 2 Distilled water fl.oz. 3 Alcohol fl.oz. 7 Mix the extract with the water, add the alcohol, and filter. — Brit. Pharm. This contains about twice the propor- tion of strychnine present in the Brit. Pharm. 1885. IV. Nux vomica, coarse powd.. av.oz. i l / 2 Distilled water fl.oz. 3^2 Alcohol fl.oz. 13 Mix, macerate for 7 days, agitating occasionally, strain with expression, and filter. — Germ. Pharm. V. Dry drug (seed, coarse pow- der) gr. 730 Distilled water fl.oz. 3% Alcohol fl.oz. 13 J4 — Homeopathic. This is intended to make 16 fluid- ounces. See Tinctures, Homeopathic, for method of preparation. This makes a ix tincture, from which dilutions are to be made with dispensing alcohol. See Dilutions, Homeopathic. Tincture of Oats. See Tincture of Avena Sativa. Tincture of Opium. (Laudanum— Tinctura Opii Simplex — Tinctura Thebaica or Meconii.) I. Opium, granulated (contain- ing 12 to 12.5 p. c. of crys- tallizable morphine) gr. 730 Alcohol, water, diluted alco- hol, to make fl.oz. 16 Heat 6 l / 2 fluidounces of water to boil- ing and pour it upon the opium con- tained in a tared vessel, weigh, and stir occasionally during 12 hours ; then re- store the original weight by the addi- 492 STANDARD FORMULARY OF tion of cold water, add 6 l / 2 fluidounces of alcohol, pour the mixture into a bot- tle, and continue the maceration for 48 hours, occasionally shaking. Transfer the mixture to a percolator, return the first portion of the percolate until it runs through clear, and, when the liquid ceases to drop, continue the percolation with enough diluted alcohol to make 16 fluidounces of percolate. — U. S. P. This tincture, when assayed, should contain not less than 1.2 nor more than 1.25 gm. of crystallizable morphine in 100 cc. This tincture was formerly made from powdered opium. II. Opium av.oz. 2^ Alcohol fl.oz. 8 Distilled water fl.oz. 8 Diluted alcohol sufficient Triturate the opium to a paste with the water, previously heated to about 95 deg. C, set aside for 6 hours, add the alcohol, mix thoroughly, set aside .in a covered vessel for 24 hours, strain, express the residue, mix the liquids, set aside for 24 hours, and filter. — Brit. Pharm. Determine the proportion of morphine present in this tincture and then dilute it with diluted alcohol so that the dilu- ted tincture will contain 24 gram of morphine (anhydrous) in each 100 cc. III. Opium, moderately fine pow- der •. av.oz. iVa Alcohol fl.oz. 7 Distilled water fl.oz. 10 Mix, macerate for 7 days, agitating occasionally, and filter. — Germ. Pharm. The product should contain about 1 per cent, of morphine. IV. The preparation of the U. S. P. is the equivalent of the homeopathic tinc- ture. This is a ix tincture. Dilutions: 2x is to be made from 1 volume of tincture, 4 of distilled water, and 5 of alcohol; 3x and higher are to be made with dispensing alcohol. See Dilutions. Homeopathic. Tincture of Opium, Acetated. Opium, powder gr. 600 Diluted acetic acid fl.oz. 8 Alcohol, to make fl.oz. 16 Make the opium and acid into an inti- mate mixture, add 8 fluidounces of alco- hol, shake well, macerate for 48 hours, filter, and through the filter add enough alcohol to make 16 fluidounces of fil- trate. — Eclectic. Tincture of Opium, Ammoniated. Tincture of opium, of the Brit. Pharm fl.oz. 2 Benzoic acid gr. 125 Ammonia water, 10 p. c. . . .fl.dr. 21 Alcohol, to make fl.oz. it, 1 / 2 Dissolve the oil and acid in 8M fluid- ounces of alcohol, add the tincture and water, mix well, filter, and add enough alcohol through the filter to make the filtrate measure 1^/2 fluidounces. — Brit. Pharm. This equals approximately 5 gr. of opium to the fluidounce. The preparation of the Brit. Pharm. 1885 was somewhat different, as fol- lows : Opium gr. 84 Spanish saffron gr. 150 Benzoic acid gr. 150 Oil of anise m. 48 Stronger ammonia water, Z2.y 2 p. c fl.oz. zV\ Alcohol sufficient Mix the first five ingredients with 13 fluidounces of alcohol, macerate for 7 days, agitating occasionally, express, fil- ter, and add enough alcohol to the fil- trate to make 16 fluidounces. Tincture of Opium, Camphorated. (Paregoric — Paregoric Elixir — Benzoated or Anisated Tincture of Opium — Compound Tincture of Camphor.) I. Opium, powder (U. S. P.)...gr. 60 Benzoic acid gr. 60 Camphor gr. 60 Oil of anise fl.dr. 1 Glycerin fl.dr. 10 Diluted alcohol fl.oz. 30 Place all the ingredients in a stop- PHARMACEUTICAL PREPARATIONS. 493 pered container, and macerate for 3 days, shaking frequently, then filter in a well-covered paper filter, adding through the filter enough diluted alcohol to make 32 fluidounces of filtrate. — U. S. P. This preparation may be made ex- temporaneously by substituting 10 fluid- drams each of tincture of opium and spirit of camphor for the opium and camphor in the above. II. The preparation of the Brit. Pharm., called "compound tincture of camphor," is as follows : Tincture of opium, of the Brit. Pharm m. 470 Benzoic acid gr. 34 Camphor gr. 25 Oil of anise m. 24 Water, alcohol, each, to make fl.oz. 16 Use a mixture of 4 volumes of water and 7 of alcohol as the solvent, dissolve the acid, camphor and oil in 14^2 fluid- ounces of this mixture, add the tincture, and then of the same mixture of alcohol and water to make 16 fluidounces, and filter if necessary. This preparation contains in each fluidram a proportion of tincture of opium (Brit. Pharm.) equivalent to about 1/30 gr. of morphine hydrochlorid or to l /i gr. of opium (containing 10 p. c. of anhydrous morphine). III. The preparation of the Germ. Pharm. called benzoated tincture of opium is as follows : Opium, No. 80 powder ..gr. 34 Oil of anise m. 35 Camphor gr. 68 Benzoic acid gr." 135 Water fl.oz. z l / 2 Alcohol fl.oz. 12^ Mix, macerate for 7 days, agitating occasionally, and filter. Tincture of Opium, Compound. This is the same as Squibb's cholera mixture. See Mixtures, Cholera, No. XII. Tincture of Opium, Crocated. (Tinc- tura Opii Crocata — Saffronized Tincture of Opium — Tincture of Opium and Saffron — Sydenham's Laudanum — Compound or Aro- matic Wine of Opium.) Opuim, granulated grs. 770 Spanish saffron gr. 200 Saigon cinnamon gr. 45 Clove gr. 45 Diluted alcohol, q. s. Triturate the drugs in a clean mortar with an equal bulk of clean sand, then rub them to a smooth paste with a por- tion of the diluted alcohol and, after macerating for two days, percolate it in the usual manner to 14 fluid ounces. Enough diluted alcohol is to be added to make the product assay 1 per cent of morphine. — N. F. Tincture of (Deodorized) Opium. Opium, granulated (contain- ing 12 to 12.5 p. c. of crys- tallizable morphine) gr. 730 Purified petroleum benzin. .fl.oz. 10 Alcohol fl.oz. zVa Water, to make fl.oz. 16 Heat 8 fluidounces of water to boiling and pour it upon the opium contained in a suitable vessel, stirring the mixture frequently during 24 hours. Then trans- fer the mixture to a percolator, return the first portion of the percolate until it runs through clear, and, when the liquid ceases to drop, continue the percolation with water until the opium is exhausted. Concentrate the percolate by evaporation on a water bath until it measures 2^/2 fluidounces, and, when cooled, shake it frequently and vigorously for ro minutes with 1 fluidounce of purified ben- zin. Separate the benzin, repeat the shaking out for a few minutes with the remainder of the benzin, and, having carefully and completely separa- ted this second portion of benzin, evap- orate the remaining liquid in a warm place spontaneously, until the odor of benzin has disappeared, removing the last traces by the heat of a water bath. Mix the deodorized liquid so obtained with g l / 2 fluidounces of water, filter the mixture through a paper filter, and hav- 494 STANDARD FORMULARY OF ing mixed the alcohol with the filtrate, wash the filter with enough water to make 16 fluidounces of filtrate. — U. S. P. The product, when assayed, should contain not less than 12 nor more than 12.5 gm. of crystallizable morphine in 100 cc. Tincture of Opium, Muriated. Opium, powder av.oz. 1 Hydrochloric acid fl.oz. 1 Water fl.oz. 15 Mix. macerate for 14 days, agitating frequently, filter, and add water through the filter to make 16 fluidounces. — Ec- lectic. Tincture of Orange. I. Bitter orange peel, fresh, cut small av.oz. 4% Alcohol fl.oz. 16 Mix, macerate for 7 days, agitating occasionally, strain with expression, and filter.— Brit. Pharm. See also Tincture of (Bitter) Orange Peel. II. Bitter orange peel, cut mod- erately fine fl.oz. 3 Water fl.oz. Z X A Alcohol fl.oz. 13 Mix, macerate for 7 days, agitating occasionally, strain with expression, and filter. — Germ. Pharm. See also Tincture of (Bitter) Orange Peel. Tincture of (Bitter) Orange Peel. (Tincture of Orange, Brit. Pharm. and U. S. P. 1870.) Bitter orange peel, No. 40 powder av.oz. 2>V\ Alcohol, water, each, to make fl.oz. 16 Prepare like tincture of calendula, using a mixture -of 3 volumes of alcohol and 2 of water as a menstruum. — U. S. P. See also Tincture of Orange. Tincture of (Sweet) Orange Peel. Sweet orange peel av.oz. S]4 Alcohol, to make fl.oz. 16 The orange peel should be from the fresh fruit, in thin shavings, and cut into narrow shreds. Macerate it in a stoppered wide-mouthed container and in a moderately warm place, with 16 fluidounces of alcohol, during 48 hours, agitating frequently; then filter through absorbent cotton, and when the liquid has drained off completely, gradually pass enough alcohol through the residue to make 16 fluidounces of tincture; final- ly, filter it through paper. — U. S. P. Tincture of Pareira. Dry drug (root) gr. 730 Distilled water fl.oz. 4^ Alcohol fl.oz. 11^4 — Homecpathic. This is intended to make 16 fluid- ounces. See Tinctures, Homeopathic, for method of preparation. This makes a ix tincture. Dilutions : 2x is to be made from 1 volume of tincture, 2 of distilled water, and 7 of alcohol; 3x and higher are to be made with dispensing alcohol. See Dilutions, Homeopathic. Tincture of Parsley. (Tincture of Petroselmum.) Fresh drug (whole plant), containing solids gr. 730 (plant moisture, av.oz. 7 l / 2 ) Alcohol fl.oz. g l / 2 — Homeopathic. This is intended to make 16 fluid- ounces. See Tinctures, Homeopathic, for method of preparation. This makes a ix tincture. Dilutions: 2x is to be made from 1 volume of tincture, 4 of distilled water, and 5 of alcohol; 3x and higher are to be made with dispensing alcohol. See Dilutions. Homeopathic. Tincture of Passion Flower. (Tinc- ture of Passiflora.) Fresh drug (leaves of the plants growing on the up- lands), containing solids... gr. 730 (plant moisture, av.oz. 6 2 /z) — Homeopathic. This is intended to make 16 fluid- ounces. See Tinctures. Homeopathic, for method of preparation. The N. F. tincfure takes 3 ounces Pas- sion flower in Xo. 30 powder, macerates PHARMACEUTICAL PREPARATIONS. 495 for 24 hours with diluted alcohol, and percolates in the usual way to make 16 fluid ounces of tincture. Tincture, Pectoral. (Guttae Pector- ales — Pectoral Drops — Bateman's Pectoral Drops.) Tincture of opium m. 320 Compound tincture of gam- bir (catechu) fl.oz. 1 Spirit of camphor fl.dr. 5 Oil of anise m. 8 Caramel fl.dr. 2 Diluted alcohol, to make. . .fl.oz. 16 Mix the first five ingredients with enough diluted alcohol to make 16 fluid- ounces, and filter. Each fluidram contains 2^ m. of tinc- ture of opium. — N. F. The formula adopted by the Philadel- phia College of Pharmacy is as follows : Opium, powder gr. 30 Catechu, powder gr. 30 Camphor gr. 30 Red saunders, rasped gr. 30 Oil of anise drops 10 Diluted alcohol fl.oz. 16^4 Macerate the saunders with the dilu- ted alcohol for 24 hours, agitating occa- sionally, filter, add the other ingredients, macerate for 10 days, agitating occasion- ally, and filter. Tincture of Pellitory. (Tincture of Pyrethrum.) Pellitory, No. 50 powder, .av.oz. 2>Ya Alcohol, to make fl.oz. 16 Prepare like tincture of calendula. — U S. P. The preparation of the Brit. Pharm. is made with a menstruum composed of 3 volumes of alcohol and 1 of water. Tincture of Pennyroyal. (Tincture of Hedeoma.) Fresh drug (whole plant), containing solids gr. 730 (plant moisture, av.oz. 5) Alcohol fl.oz. u^4 — Homeopathic. This is intended to make 16 fluid- ounces. See Tinctures, Homeopathic, for method of preparation, This is a ix tincture. Dilutions: 2x is to be made from 1 volume of tincture, 2 of distilled water, and 7 of alcohol ; 3x and higher are to be made with dis- pensing alcohol. See Dilutions, Homeo- pathic. Tincture of Peppermint. (Tincture of Mentha Piperita.) Fresh drug (whole plant), containing solids gr. 730 (plant moisture, av.oz. 6^3) Alcohol fl.oz. io^4 — Homeopathic. This is intended to make 16 fluid- ounces. See Tinctures, Homeopathic, for method of preparation. This is a ix tincture. Dilutions : 2x is to be made from 1 volume of tincture, 3 of distilled water, and 6 of alcohol; 3x and higher are to be made with dis- pensing alcohol. See Dilutions. Homeo- pathic. Tincture of Phosphorus. Take of phosphorus an excess (15 grains or more) and introduce this into a flask containing 16 fluidounces of alcohol. Heat on a water bath until the phosphorus is melted, then shake vigor- ously until any excess of the phosphorus is solidified. — Homeopathic. This saturated solution will equal in drug strength about 1 part in 667. To compensate for loss by oxidation, and so retain the full strength of the solu- tion, a small piece of phosphorus should be kept in each bottle containing the tincture, the same to be renewed when- ever it becomes coated with the amor- phous variety. The spirit of phosphorus U. S. P. is one-fourth weaker than the above (1 in 833). Dilutions : 3x is made by mixing 2 volumes of tincture with I of alcohol (or 4 volumes of U. S. P. spirit with 1 of alcohol) ; 4.x and higher are to be made with alcohol. See Dilutions, Ho- meopathic. Tincture of Phosphorus, Compound. Phosphorus gr. 10 Chloroform fl.oz. 2 Absolute alcohol fl.oz. 10 Place the phosphorus with the chloro- form in a stoppered bottle, apply the heat of a water bath until dissolved, and 496 STANDARD FORMULARY OF then add this to the alcohol, and shake well. This tincture should be protected from the light, in accurately stoppered bottles. It deteriorates if long kept. Each fluidram contains about i/io gr. of phosphorus. — Brit. Form. Tincture of Pimpinella. Pimpinella root av.oz. 2^4 Alcohol, water, each, to make fl.oz. 16 Mix 2 volumes of alcohol with I of water. Macerate the drug, reduced to a moderately coarse (No. 40) powder, with enough of the menstruum to keep it distinctly damp during 12 hours. Then percolate it with the same menstruum, in the usual manner, until 16 fluidounces of tincture are obtained. This preparation is approximately of the same strength as that which is offi- cial in the Germ. Pharm.— N. F. The latter preparation is made by macerating 3 av. ounces of pimpinella, cut moderately fine, for 7 days with 3^2 fluidounces of water and 13 fluidounces of alcohol, straining with expression, and filtering. Tincture of Plantain. (Tincture of Plantago.) Fresh drug (whole plant), containing solids _ gr. 730 (plant moisture, av.oz. 5.6) Alcohol fl.oz. 11 — Homeopathic. This is intended to make 16 fluid- ounces. See Tinctures, Homeopathic, for method of preparation. This makes a ix tincture. Dilutions : 2x is to be made from 1 volume of tincture, 3 of distilled water, and 6 of alcohol ; 3x and higher are to be made with dispensing alcohol. See Dilutions, Homeopathic. Tincture of Pleurisy Root. (Tinc- ture of Butterfly Weed or Asclep- ias Tuberosa.) Fresh drug (root), contain- ing solids gr. 730 (plant moisture, av.oz. 3.9) Distilled water fl.oz. 2^4 Alcohol fl.oz. io}4 — Homeopathic. This is intended to make 16 fluid- ounces. This is a ix tincture. See Tinctures, Homeopathic, for method of preparation. Dilutions : 2x are to be made from 1 volume of tincture, 3 of distilled water, and 6 of alcohol; 3x and higher are to be made with dispensing alcohol. See Dilutions, Homeopathic. Tincture of Podophyllin. There are several formulas. Martin- dale (Extra Pharmacopeia) mentions the following: I. Dobell's : Podophyllin gr. 1 Tincture of ginger fl.dr. 1 Alcohol, to make fl.oz. 1 The dose is a teaspoonful in water at bed-time, every night or every second, third, or fourth night, as required. This is reputed to act more satisfactorily than podophyllin in pills. II. Ringer's : Podophyllin gr. 1 Alcohol fl.dr. 1 This dose is 2 to 4 drops in tea or coffee, taken night and morning, and is useful in sick headache and biliousness, where the bowels and liver are sluggish, in worried and overworked patients, and in chronic diarrhea with cutting pains and high-colored stools. The taste is acrid and disagreeable. III. Ammoniated Tincture: Podophyllin gr. 1 Aromatic spirit of ammonia, .fl.dr. 1 The dose is 2 to 6 minims as an altera- tive, 10 to 20 minims as a purgative and cholagogue, taken in a wineglassful of water or milk. Podophyllin will dis- solve perfectly in the spirit. This tinc- ture has the advantage that it can be mixed with water, without causing the resin to separate. The vehicle also acts as a corrective. Tincture of Podophyllum. See Tincture of May Apple. Tincture of Poison Ivy. (Tincture of Poison Oak or Rhus Toxicoden- dron — Tincture of Toxicodendri.) I. Poison ivy, fresh leaves av.oz. 8 Alcohol fl.oz. 6 PHARMACEUTICAL PREPARATIONS. 497 Macerate for 14 days, express and fil- ter in a well-covered funnel. — Eclectic. This should be preserved in well-stop- pered vials. II. Fresh drug (leaves), con- taining solids gr. 730 (plant moisture, av.oz. 2>Yz) Alcohol fl.oz. 13^ — Homeopathic. This is intended to make 16 fluid- ounces. See Tinctures, Homeopathic, for method of preparation. This makes a ix tincture, from which dilutions are to be made with dispensing alcohol. See Dilutions, Homeopathic. Great. care must be exercised in han- dling this drug. The tincture also poi- sons the skin and it also should be handled with great care. Tincture of Poke. (Tincture of Phy- tolacca.) Poke root, recently dried, fine powder av.oz. 3 Diluted alcohol, to make fl.oz. 16 Extract the drug by percolation or maceration. — Eclectic. Tincture of Poke, Compound. This formula has been recommended and used: Fluid ext. of poke root fl.oz. 3 Tincture of cardamom fl.dr. 10 Diluted alcohol, to make. .. .fl.oz. 16 Tincture of Poppy. (Tinctura Papa- veris.) Poppy capsules, freed . from seeds, in coarse powder, .av.oz. 8^4 Glycerin fl.oz. 2 Alcohol, water, each, to make fl.oz. 16 Digest the poppy capsules with 48 fluidounces of boiling water during 2 hours, then express and strain. Evap- orate the strained liquid to 8 fluidounces, mix it with 4 fluidounces of alcohol, and set the mixture aside, well covered, until it is quite cold. Then filter, add the glycerin to the filtrate, and pass enough of a mixture of 2 volumes of water and 1 of alcohol through the filter to make the product measure 16 fluid- ounces. Each fluidram represents 30 gr. of poppy capsule freed from seeds.- This is used for making syrup of poppy. Tincture of Prickly- Ash Berries. Prickly-ash berries, fine pow- der av.oz. 4 Diluted alcohol, to make .... fl.oz. 16 Extract the drug by percolation or maceration. — Eclectic. Tincture of Prickly-Elder. (Tinctura Araliee SpinosEe.) Prickly-elder bark, fine pow- der av.oz. 3 Diluted alcohol, to make. . .fl.oz. 16 Make into a tincture by percolation or maceration — Eclectic. Tincture of Puff Ball. (Tincture of Bovista.) The ripe fungus, in dry pow- der gr. 730 Distilled water fl.oz. 6 l / 2 Alcohol fl.oz. io^4 —Homeopathic. This is intended to make 16 fluid- ounces. This makes a ix tincture. See Tinctures, Homeopathic, for method of preparation. Dilutions are to be made with dis- pensing alcohol. See Dilutions, Homeo- pathic. Tincture of Pulsatilla. Pulsatilla, No. 30 po oz. V/ 2 Alcohol Water, q. s. Macerate with 3 volumes alcohol and 1 oz. water for six hours, and percolate with same menstruum to 16 n. ozs. II. Homeopathic formula (from the American Homeopathic Pharmaco- peia) : The fresh, plant, gathered when in flower, is chopped and pounded to a pulp and weighed. Then two parts by weight of alcohol are taken, the pulp mixed thoroughly with one-sixth part of it. and the rest of the alcohol added. After having stirred the whole, pour it into a well-stoppered bottle, and let it stand 8 days in a dark, cool place. The tincture is then separated by decanting, straining and filtering. 498 STANDARD FORMULARY OF III. Pulsatilla, No. 20 powder gr. 730 Alcohol, water, each, to - make fl.oz. 16 Extract the drup- by percolation with a mixture of 9 volumes of alcohol with 5 of water. — Brit. Form. Tincture of Quassia. I. Quassia, No. 50 powder. . .av.oz. 2>Va Alcohol, water, each, to make fl.oz. 16 Prepare like tincture of black cohosh, using as a menstruum a mixture of 7 volumes of alcohol and 13 of water — U. S. P. II. Quassia, rasped gr. 730 Diluted alcohol fl.oz. 16 Mix, macerate for 7 days, agitating occasionally, strain with expression, and filter.— Brit. Pharm. Tincture of Quinine. Quinine hydrochlorid gr. 145 Tincture of orange fl.oz. 16 Mix and dissolve. — Brit. Pharm. Tincture of Quinine, Ammoniated. Quinine sulfate gr. 145 Ammonia water fl.dr. 13 Distilled water fl.oz. S l A Alcohol fl.oz. 9/4 Mix the ammonia water, water and alcohol, add the quinine salt, shake until a clear solution is obtained, set aside for. 3 days, and filter. — Brit. Pharm. Tincture of Quinine, Compound. (Ague Bitters.) Quinine (alkaloid) gr. 30 Potassium bitartrate av.oz. 1 Clove, powder av.oz. 1 Diluted alcohol fl.oz. 16 Macerate for 24 hours, occasionally agitating, and filter. — Eclectic. Tincture of Red Clover. (Tincture of Trifolium Pratense.) Fresh drug (flower-heads), containing solids gr. 730 (plant moisture, av.oz. 5) Alcohol fl.oz. ii54 — Homeopathic. This is intended to make 16 fluid- ounces. See Tinctures, Homeopathic, for method of preparation. This makes a ix tincture. Dilutions : 2x is to be made from 1 volume of tincture, 2 of distilled water, and 7 of alcohol ; 3x and higher are to be made with dispensing alcohol. See Dilutions, Homeopathic. Tincture of Rhatany. (Tincture of Krameria — Tinctura Ratanhia.) I. Krameria, No. 40 powder, .av.oz. 2> l A Diluted alcohol, to make. .. .fl.oz. 16 Prepare like tincture of calendula, using diluted alcohol as a menstruum. — N. F. II. The preparation of the Brit. Pharm. is made with a mixture of 7 volumes of alcohol and 4 of water. The drug strength is the same as that of the N. F. III. Rhatany, cut moderately fine av.oz. 3 Water fl.oz. 2,y 2 Alcohol fl.oz. 13 Mix, macerate for 7 days, agitating occasionally, strain with expression, and filter. — Germ, and Austr. Pharms. IV. Dry drug (root) gr. 730 Distilled water fl.oz. 8 Alcohol fl.oz. 8. .fl.dr. 5 — Homeopathic. This is intended to make 16 fluid- ounces. See Tinctures, Homeopathic, for method of preparation. This makes a ix tincture. Dilutions : ix is to be made from 1 volume of tincture, 4 of distilled water, and 5 of alcohol ; 3x and higher are made with dispensing alcohol. See Dilutions, Ho- meopathic. Tincture of Rhubarb. I. Rhubarb av.oz. Z l A Cardamom gr. 290 Glycerin fl.dr. 13 Alcohol, water, each to make fl.oz. 16 Mix the glycerin with 8 fluidounces of alcohol and 6Y 2 fluidounces of water. Reduce the drugs to No. 40 powder and moisten with i l / 2 fluidounces of men- PHARMACEUTICAL PREPARATIONS. 499 struum; transfer it to a percolator, and, without pressing the drug, allow it to stand, well covered, for 12 hours ; then pack it moderately and pour on enough menstruum to saturate the drug and leave a stratum above it. When the liquid begins to drop from the percola- tor, close the lower orifice, and macerate for 24 hours. Then allow percolation to proceed slowly, pouring on, first, the re- mainder of the menstruum, and then enough of a mixture of 5 volumes of alcohol and 4 of water to make 16 fluidounces of tincture. — U. S. P. This preparation is twice the strength of that of the U. S. P. 1890. II. The closely related preparation of the Brit. Pharm. is called compound tincture of rhubarb. See Tincture of Rhubarb, Compound. III. Dry drug gr. 730 Distilled water fl.oz. 6 l / 2 Alcohol fl.oz. 10^ — Homeopathic. This is intended to make 16 fluid- ounces. See Tinctures, Homeopathic, for method of preparation. This is of the same strength as the. U. S. P. tincture but contains neither cardamom nor glycerin. It is a ix tincture from which a 2x dilution is to be made by mixing 1 volume of tinc- ture with 3 of distilled water and 6 of alcohol; 3x and higher dilutions are to be made with dispensing alcohol. See Dilutions, Homeopathic. Tincture of Rhubarb, Aqueous. (Alkaline Infusion of Rhubarb.) I. Rhubarb gr. 720 Borax \ gr. 72 Potassium carbonate gr. 72 Cinnamon water. fl.oz. 2 Alcohol fl.oz. iM Water, to make fl.oz. 16 Dissolve the borax and potassium car- bonate in 12 fluidounces of water, and macerate in this solution, during 24 hours, the rhubarb, cut into thin slices and carefully freed from any adhering fine powder. Then strain it through 32 muslin, heat the strained liquid to boil- ing, add the cinnamon water and alco- hol, s.tir it well and filter, while warm, in a covered funnel. To the cold filtrate add enough water to make the product measure 16 fluidounces. Each fluidram represents about sH' S r - of rhubarb. The product is practically identical with that obtained by the process of the Germ. Pharm., in which this preparation is official. It is liable to deteriorate when kept too long, and should not be prepared in larger quantity than may be consumed v/ithin a short time. II. When this preparation is required tor immediate use, and it is not other- wise obtainable, it may be prepared in the following manner (according to the N. F.) : Fluid extract of rhubarb. . .fl. dr. 13 Borax gr. 72 Potassium carbonate gr. 72 Cinnamon water fl.oz. 2 Alcohol fl.dr. 6 l / 2 Water, to make fl.oz. 16 Dissolve the borax and potassium carbonate in about 8 fluidounces of water. Add the cinnamon water, alco- hol, and fluid extract, and lastly, enough water to make the product measure 16 fluidounces. Filter, if necessary. — N. F. Tincture of Rhubarb, Aromatic. Rhubarb av.oz. 2>Ya Saigon cinnamon gr. 290 Clove gr. 290 Nutmeg ' gr. 145 Glycerin fl.dr. 13 Alcohol, water, each, to make fl.oz. 16 Prepare exactly like tincture of rhu- barb.— U. S. P. Tincture of Rhubarb, Compound. I. Rhubarb gr. 350 Bitter-root (dogsbane) gr. 175 Golden seal gr. 175 Gentian gr. 175 Prickly ash berries gr. 175 Sassafras gr. 88 Cardamom seed gr. 88 Diluted alcohol, to make.. fl.oz. 16 Mix the drugs, reduce to moderately fine powder, and extract by percolation :>oo STANDARD FORMULARY OF or maceration with diluted alcohol so as to obtain 16 fluidounces of percolate. — Eclectic. II. The Brit. Pharm. preparation given here is closely allied to the tinc- ture of rhubarb of the U. S. P. : Rhubarb, No. 20 powder gr. 730 Cardamom, bruised gr. 92 Coriander gr. 92 Glycerin fl.dr. 13 Alcohol, water, each, to make fl.oz. 16 Mix the alcohol and water in the pro- portion of 7 volumes of the alcohol to 4 of the latter, moisten the mixed drugs with 13 fluidrams of this menstruum, extract by percolation so as to obtain 14^ fluidounces of liquid, set aside for 48 hours, filter, and add the glycerin. Tincture of Rhubarb and Gentian. I. Rhubarb gr. 512 Gentian gr. 128 Diluted alcohol, to make. . .fl.oz. 16 Reduce the solids to a moderately coarse (No. 40) powder, and percolate it, in the usual manner, with diluted alcohol, until 16 fluidounces of percolate are obtained. Each fluidram represents 4 gr. of rhu- barb and 1 gr. of gentian. II. When this preparation is required for immediate use, and it is not other- wise obtainable, it may be prepared in the following manner (according to the N. F.) : Fluid extract of rhubarb. . .fl.dr. 8 l / 2 Fluid extract of gentian m. 128 Diluted alcohol to make. . .fl.oz. 16 Mix the fluid extracts with enough diluted alcohol to make 16 fluidounces, and filter. Tincture of Rhubarb, Koelreuter's. Rhubarb, cut av.oz. 2 l / 2 Bitter orange peel, cut fine. .gr. 360 European centaury, cut fine..gr. 180 Fennel, bruised av.oz. % Alcohol fl.oz. g l / 2 Distilled water .fl.oz. 8 Mix, macerate for 7 days, agitating occasionally, strain with expression, and filter.— D. Tincture of Rhubarb and Senna. (Warner's Gout Cordial.) Rhubarb gr. 160 Senna gr. 40 Coriander gr. 20 Fennel gr. 20 Licorice gr. 10 Raisins, deprived of seeds. av.oz. 2% Diluted alcohol fl.oz. 16 Mix, macerate for 7 days, agitating occasionally, express and filter. — U. S. P. 1870. Tincture of Rhubarb, Sweet. Rhubarb gr. 720 Licorice root gr. 290 Anise gr. 290 Cardamom gr. 72 Glycerin fl.oz. iy 2 Alcohol, water, diluted alco- hol, each, to make fl.oz. 16 — N. F. Appendix and U. S. P. 1890. Prepare exactly like Tincture of Rhu- barb, Aromatic, which see. Tincture of Rhubarb, Vinous. I. Fluid extract of rhubarb. . .fl.dr. 10 Fluid extract of bitter orange peel fl.dr. 2^ Tincture of cardamom fl.dr. 10 Sugar av.oz. 2 Sherry wine, to make fl.oz. 16 Mix the fluid extracts and tincture with 8 fluidounces of sherry wine. In this dissolve the sugar by agitation, then add enough sherry wine to make 16 fluidounces," and filter. — N. F. This preparation corresponds approxi- mately, in strength, to that which is offi- cial in the Germ. Pharm. II. The process of the Germ. Pharm. is as follows : Rhubarb, cut fine gr. 580 Bitter orange peel, cut fine.-gr. 145 Cardamom, bruised gr. 72 Sherry wine " fl.oz. 16 Sugar sufficient Macerate the drugs and the wine "for 7 days, occasionally agitating, filter, to the filtrate add one-seventh its weight of sugar, and dissolve by agitation. Tincture of Saffron. (Tincture of Crocus.) I. Spanish saffron gr. 360 Diluted alcohol, to make. . .fl.oz. 8 PHARMACEUTICAL PREPARATIONS. 501 Moisten the drug with 13 fluidounces of diluted alcohol, macerate for 24 hours ; then pack firmly in a cylindrical percolator, and gradually pour diluted alcohol upon it until 8 fluidounces of percolate are obtained. — N. F. II. Spanish saffron gr. 365 Water fl.oz. sVa Alcohol fl.oz. ioJ4 occasionally, strain with expression, and Mix, macerate for 7 days, agitating filter.— Brit. Pharm. III. Spanish saffron, cut fine... av.oz. 1^2 Water fl.oz. 3^ Alcohol fl.oz. 13 Mix, macerate for 7 days, agitating occasionally, strain with expression, and filter. — Germ. Pharm. (2nd). IV. The Homeopathic tincture is to be prepared of same strength as that of U. S. P., but using alcohol as the men- struum. This makes a ix tincture, from which dilutions are made with dis- pensing alcohol. See Dilutions, Homeo- pathic. Tinctures, Saturated. These are described by Eclectics as preparations made by saturating a men- struum with as much of a drug as it will " take up. This expression, now practically obsolete, is at present usually assumed to mean a fluid extract. Some tinctures, which are prepared by solu- tion, such as tincture of iodin, are actu- ally saturated or nearly saturated tinc- tures. Tincture of Savin. Savin, coarse powder av.oz. 2 Diluted alcohol, to make fl.oz. 16 Extract the drug by percolation. —Brit. Pharm. 1885. Tincture of San Palmetto and Santal. San palmetto oz. V/ 2 Sandalwood Alcohol Water, each, a sufficient quantity. Mix four volumes of alcohol with one volume of water and saturate the drug with this menstruum. Macerate four days and percolate with same drug to 16 fluid ounces. — N. F. Tincture of Senega. Senega root, No. 40 powd.. av.oz. 3% Alcohol, water, each, to make fl.oz. 16 Extract the drug by percolation with a mixture of 7 volumes of alcohol and 4 of water. — Brit. Pharm. Tincture of Senna, Compound. (Tinc- ture of Senna, Brit. Phar. 1885 — Elixir Salutis— Elixir of Health —Daffy's Elixir.) Senna, cut av.oz. 3% Caraway, bruised gr. 185 Coriander, bruised gr. 185 Raisins, freed from seeds.... gr. 730 Diluted alcohol fl.oz. 16 Mix, macerate for 7 days, agitating occasionally, strain with expression, and filter.— Brit. Pharm. The former formula of the Edinburgh Pharmacopeia was about as follows : Alexandria senna, cut av.oz. 1 Jalap, fine powder av.oz. x / 2 Coriander av.oz. % Raisins, deprived of seeds. av.oz. i>4 Brandy or diluted alcohol. ..fl.oz. 16 Macerate for 7 days, shaking occa- sionally, and filter. Tincture of Serpentaria. (Tincture of Virginia Snakeroot.) Serpentaria, No. 50 powd.. av.oz. 3% Alcohol, water, each, to make fl.oz. 16 Prepare like tincture of black cohosh, using as a menstruum a mixture of 13 volumes of alcohol and 7 of water. — N. F. II. Serpentaria, No. 40 powd.. av.oz. 3% Alcohol, water, each, to make fl.oz. 16 Extract the drug by percolation with a mixture of 3 volumes of alcohol and I of water. — Brit. Pharm. 502 STANDARD FORMULARY OF Tincture of Serpentaria, Compound. (Sudorific Tincture.) Serpentaria, fine powder gr. 145 Ipecac, fine powder gr. 145 Spanish saffron gr. 145 Camphor ...gr. 145 Opium, moderately coarse powder gr. 145 Diluted alcohol or Holland gin .fl.oz. 16 Macerate the drugs with the diluted alcohol or gin for 14 days, agitating oc- casionally, express, and filter.— Eclectic. The preparation may also be made by percolation. Some Eclectic physicians object to the opium in the above and substitute 585 grains of ladies' slipper root for it. Tincture of Sheep-Laurel. (Tinctura Kalmia or Mountain Mint.) Sheep-laurel leaves, coarse powder av.oz. 3 Diluted alcohol, to make fl.oz. 16 Prepare a tincture by percolation or maceration. — Eclectic. Tincture of Shepherd's Purse. (Tinc- tura Bursa? Pastoris — Tincture of Capsella or Bursa Pastoris.) I. Shepherd's purse herb, fresh- ly gathered, Alcohol, each, .equal parts by weight Contuse the herb to pulp, add the al- cohol, macerate for several days, ex- press, and filter. — H. II. Fresh drug (whole plant), containing solids gr. 730 (plant moisture, av.oz. 3.9) Distilled water fl.oz. Z X A Alcohol fl.oz. 9. .fl.dr. 5 — Homeopathic. This is intended to make 16 fluid- ounces. See Tinctures, Homeopathic, for method of preparation. This is a ix tincture. Dilutions: 2x is to be made from 1 volume of tincture, 3 of distilled water, and 6 of alcohol ; 3x and higher are to be made with dispensing alcohol. See Dilutions, Ho- meopathic. Tincture of Skunk Cabbage. I. Skunk cabbage, recently dried, fine powder av.oz. 3 Diluted alcohol, to make. . . .fl.oz. 16 Extract the drug by percolation or maceration. — Eclectic. II. (This is also called Tincture of Pothos Foetidus) : Fresh drug (root), contain- ing solids gr. 730 (plant moisture, av.oz. 8^3) Alcohol fl.oz. 8..fl.dr. 5 — Homeopathic. This is intended to make 16 fluid- ounces. See Tinctures, Homeopathic, for method of preparation. This makes a ix tincture. Dilutions : 2x is to be made from 1 volume of tincture, 4 of distilled water, and 5 of alcohol; 3x and higher are to be made with dispensing alcohol. See Dilutions. Homeopathic. Tincture of Smart Weed. (Tincture of Water Pepper, Polygonum Punctatum, or Polygonum Hy- dropiperoides.) I. Fresh drug (whole plant), containing solids gr. 730 (plant moisture, av.oz. 5) Alcohol fl.oz. 1134 — Homeopathic. This is intended to make 16 fluid- ounces. See Tinctures, Homeopathic, for method of preparation. This makes a ix tincture. Dilutions : 2x is to be made from 1 volume of tincture, 2 of distilled water, and 7 of alcohol; 3x and higher are to be made with dispensing alcohol. See Dilutions, Homeopathic. II. Smart weed, fresh herb, enough to fill a jar, Holland gin or diluted alco- hol, enough to fill the jar. Macerate for 7 days, express, and fil- ter. Or it may be prepared from 4 av.- ounces of the powdered dry drug and enough diluted alcohol to make 16 fluid- PHARMACEUTICAL PREPARATIONS. 503 ounces, extracting the drug by percola- tion or maceration. — Eclectic. Tincture of (Green) Soap. See Liniment of Soft Soap. Tincture of Soap Bark. (Tincture of Quillaja or Quillaia.) I. Soap bark, No. 20 powder. av.oz. 6Y4. Alcohol fl.oz. 11 Water, to make fl.oz. 32 Boil the drug in a covered vessel with 26 fluidounces of water for 15 minutes, strain while hot, and wash the residue on the strainer with 6 l / 2 fluidounces of water, previously heated to boiling. Then evaporate the strained liquid to 20 fluid- ounces, allow it to cool, add the alcohol, and set it aside for 12 hours. Decant the clear liquid, filter it through paper, then pour the residue on the filter, and when the liquid ceases to drop, wash the filter with enough water to make 32 fluidounces of filtrate. — N. F. II. Soap bark, No. 20 powder... gr. 365 Alcohol, water, each, to make fl.oz. 16 Extract the drug by percolation with a mixture of 7 volumes of alcohol and 4 of water. — Brit. Pharm. III. Dry drug gr. 730 Distilled water fl.oz. 8 Alcohol fl.oz. 8. .fl.dr. 5 — Homeopathic. This is intended to make 16 fluid- ounces. See Tinctures, Homeopathic, for method of preparation. This makes a ix tincture. Dilutions : 2x is to be made from 1 volume of tincture, 4 of distilled water, and 5 of alcohol; 3x and higher are to be made with dispensing alcohol. See Dilutions, Homeopathic. Tincture of Spearmint. (Spirit of Mint.) Spearmint, fresh herb, to fill a glass jar, Holland gin, to cover the herb. Macerate for 7 days, express, and fil- ter.— Eclectic. Tincture of Spider Web. Spider web, clean and recent- ly spun av.oz. 2 Alcohol fl.oz. 16 Mix, macerate for 10 days, and filter. — Eclectic. Tincture of Sponge or Spongia. Sponge ..gr. 183 Distilled water fl.dr. &/ 2 Alcohol fl.dr. 26^ — Homeopathic. This is intended to make 4 fluid- ounces. See Tinctures, Homeopathic, for method of preparation. The kind of sponge known as Turkey sponge should be used, and should be unbleached. The sponges selected should be carefully freed from all foreign sub- stances, cut into small pieces and then roasted until brown and friable. The above forms a ix tincture, from which dilutions are to be made with dispensing alcohol. Tincture of Squill. I. Squill, No. 20 powder av.oz. iji Alcohol, water, to make fl.oz. 16 Mix alcohol and water in the propor- tion of 3 volumes of the former to 1 of the latter. Macerate the drug with g l / 2 fluidounces of menstruum, in a closed vessel, in a moderately warm place for 3 days, occasionally stirring, and then express the liquid with strong expression. Macerate the residue with 5 fluidounces of menstruum for one day before expression; and finally repeat the operation with enough menstruum to make 16 fluidounces of product, macera- ting this time for 6 hours. Mix the three liquids, filter through paper, and pass enough menstruum through the fil- ter to make 16 fluidounces of filtrate. — U. S. F. II. Squill, bruised av.oz. 2>Va Water fl.oz. $Va Alcohol fl.oz. ioJ4 Mix, macerate for 7 days, agitating occasionally, strain with expression, and filter —Brit. Pharm. 504 STANDARD FORMULARY OF III. Squill, cut moderately fine, av.oz. 3 Water fl.oz. 3 l A Alcohol fl.oz. 13 Mix, macerate for 7 days, agitating occasionally, strain with expression, and filter. — Germ. Pharm. Tincture of Star Grass. (Tincture of Aletris Farinosa.) Fresh drug (root), contain- ing solids gr. 730 (plant moisture, gr. 1460 — a total of av.oz. 5.) Distilled water fl.oz. 3 T A Alcohol fl.oz. io34 — Homeopathic. This is intended to make 16 fluid- ounces. It is a ix tincture. See Tinctures, Homeopathic, for method of preparation. Dilutions: 2x is to contain 1 volume of tincture, 2 of distilled water, and 7 of alcohol. The higher are to be made with dispensing alcohol. See Dilutions, Homeopathic. Tincture of Stavesacre. (Tinctura Staphisagriae.) Stavesacre seed, fine powd. av.oz. 10 Absolute alcohol, to make.. fl.oz. 16 Extract the drug by maceration or percolation. — Eclectic; Tincture of Stillingia. (Tincture of Queen's Root.) Stillingia, recent, cut into small pieces and bruised. av.oz. 3 Diluted alcohol, to make fl.oz. 16 Extract the drug by percolation or maceration. — Eclectic. Tincture of St. John's- Wort. (Tinc- ture Hyperici.) St. John's-wort flowers, fresh av.oz. 5 Alcohol fl.oz. 16 Mix, macerate for 14 days, express, and filter. — Eclectic. Tincture of Stramonium. Stramonium leaves, No. 60 powder (containing not less than 0.35 per cent, of mydriatic alkaloids) ....av.oz. 1% Diluted alcohol, to make fl.oz. 16 Prepare like tincture of belladonna leaves.. The product, when assayed, should contain 0.03 gm. of mydriatic alkaloids in 100 cc— U. S. P. The preparation of the Brit. Pharm. is twice the strength of this preparation and is also made with diluted alcohol. The tincture of stramonium of the U. S. P. 1890 was made from the seed. See Tincture of Stramonium Seed. Tincture of Stramonium Seed. Stramonium seed, No. 40 powder av.oz. 2^/2 Diluted alcohol, to make fl.oz. 16 Moisten the drug with ij^ fluidounces of menstruum, macerate for 24 hours, pack it firmly in a cylindrical percolator, and gradually pour menstruum upon it until 16 fluidounces of percolate are ob- tained. — N. F. Appendix and U. S. P. 1890. Tincture of Strophanthus. I. Strophanthus, No. 60 powd. av.oz. \Y\ Alcohol, water, each, to make fl.oz. 16 Moisten the drug with 6^ fluidrams of a mixture of 13 volumes of alcohol and 7 of water, transfer this to a perco- lator, and without pressing the drug, allow it to stand, well covered, for 6 hours; then pack it firmly and pour on enough of the same menstruum to sat- urate the drug and leave a stratum above it. When the liquid begins to drop from the percolator, close the low- er orifice, and, having closely covered the percolator, macerate for 48 hours. Then allow percolation to proceed slow- ly, pouring on enough menstruum to make 16 fluidounces of percolate. — U. S. P. This tincture heretofore has been of the strength of 5 per cent, but is now 10 per. cent. Also in nearly all the other processes, such as that of the 1st N. F., the drug was first extracted with stronger ether to remove oil, then dried, and subsequently extracted with alcohol to prepare the tincture, the ethereal ex- tract being rejected. The extraction with a hydro-alcoholic menstruum, with- PHARMACEUTICAL PREPARATIONS. 505 out the preliminary use of ether, has been found to be satisfactory and is also the process of the Brit. Pharm. The drug used is the ripe seed of Strophanthus Kombe, deprived of its long awn. II. Strophanthus seed, No. 30 powder av.oz. y 2 Alcohol, water, each, to make fl.oz. 20 Mix alcohol and water in the propor- tion of 3 volumes of the former to 1 of the latter, pack the drug in a percolator, moisten it with 1 fluidram of the men- struum, set aside for 48 hours, pour on successive quantities of menstruum, al- lowing percolation to proceed slowly, until 10 fluidounces of percolate have been obtained, filter, and add enough menstruum to make 20 fluidounces. — Brit. Pharm. This preparation is only half the strength of the corresponding prepara- tion of the Brit. Pharm. 1885 (additions of 1890) and one-fourth of that of the U. S. P. III. Strophanthus seed av.oz. i]/ 2 Water fl.oz. 3 J / 2 Alcohol fl.oz. 13 Contuse the drug, remove the fixed oil as much as possible by expression, then reduce to moderately fine powder, macerate this with the alcohol and water for 7 days, agitating occasionally, and filter (without previous expression). If the filtrate is turbid, refilter it through purified talcum. — Germ. Pharm. This preparation is of the same strength as the corresponding prepara- tion of the U. S. P. The strophanthus to be used are the seeds of Strophanthus hispidus and Kombe. IV. Strophanthus powder av.oz. Y\ Alcohol, stronger ether, each sufficient Extract the drug with the ether to remove fixed oil, then dry the drug, and extract with alcohol so as to obtain 15 av.ounces of tincture. — Austr. Pharm. Tincture of Strychnine. (Magendie's Tincture of Strychnine.) This solution has been known by this title : Strychnine (alkaloid) gr. 3 Alcohol fl.oz. 1 Agitate occasionally until dissolved. Tinctura strychni of the Germ. Pharm. is tincture of nux vomica and should not be confounded with the above. Tincture of Strychnine, Compound. Strychnine (alkaloid) gr. 16 Acetic acid fl.dr. 4 Compound tincture of carda- mom fl.dr. 4 Distilled water fl.oz. 7^ Alcohol fl.oz. 7V 2 Dissolve the strychnine in the alcohol and acetic acid, add the remaining in- gredients, and filter. — Eclectic. Tincture of Sulfur. (Spirit of Sul- fur.) I. The Homeopathic tincture is a solu- tion of sublimed sulfur in alcohol of the strength of 1 to 5000 (1 gm. to 5000 cc. or 1 gr. to 87^2 fl.dr. or approximately 1 gr. to 11 fluidounces). 4x dilution is to be made by mixing equal volumes of this tincture and alcohol. II. Washed sulfur gr. 75 Absolute alcohol fl.oz. 4 Mix, macerate for 4 days, agitating occasionally, and filter in a well-covered funnel. — H. Tincture of Sumbul. (Tincture of Musk Root.) I. Sumbul, No. 30 powder av.oz. i l / 2 Alcohol, water, each, to make fl.oz. 14^ Mix alcohol and water in the propor- tion of 13 volumes of alcohol to 7 of water. Moisten the drug with 13 fluid- drams of this menstruum, macerate for 24 hours, then pack firmly in a cylin- drical percolator, and gradually add menstruum until 14^2 fluidounces of the percolate are obtained, 106 STANDARD FORMULARY OF II. The preparation of the Brit. Pharm. differs from the above only in being made with a mixture of 3 vol- umes of alcohol and 1 of water. III. Dry drug gr. 730 Distilled water fl.oz. 3 l A Alcohol ..fl.oz. 1354 — Homeopathic. This is intended to make 16 fluid- ounces. This corresponds to the U. S. P. preparation, but is made with a slightly more alcoholic menstruum. This makes a ix tincture, from which dilutions are to be made with dispensing alcohol. See Dilutions, Homeopathic. Tincture of Sweet Sumach. (Tincture of Fragrant Sumach or Rhus Aromatica.) Fresh drug (leaves), con- taining solids gr. 730 (plant moisture, av.oz. 3.9) Distilled water fl.dr. 13 Alcohol fl.oz. ii54 — Homeopathic. This is intended to make 16 fluid- ounces. See Tinctures, Homeopathic, for method of preparation. This is a ix tincture. Dilutions: 2x is to be made from 1 volume of tincture, 2 of distilled water, and 7 of alcohol; 3x and higher are to be made with dis- pensing alcohol. See Dilutions, Homeo- pathic. Tincture of Tansy, Compound. Tansy, coarse powder av.oz. I Swamp milkweed, coarse powder av.oz. Yi Unicorn root, coarse powd. av.oz. % Prickly-ash berries, coarse powder av.oz. X A Diluted alcohol fl.oz. 16 Macerate for 14 days, agitating occa- sionally, and filter. — Eclectic. Tincture of Thuja. (Tincture of Arbor Vitae.) Thuja, fresh tops av.oz. y/ 2 Alcohol, to make fl.oz. 16 Macerate the drug for 7 days with 16 fluidounces of alcohol, pour off the liquid, and express the remainder. Treat the latter with fresh portions of alcohol, forcibly expressing each time, until the whole, when filtered, measures 16 fluid- ounces. Tincture of Tobacco. (Tincture of Tabacum.) Drug (the recently dried leaves. those imported from Havana being pre- ferred) gr. 730 Distilled water fl.oz. 3% Alcohol fl.oz. 1314 — Homeopathic. This is intended to make 16 fluid- ounces. See Tinctures, Homeopathic, for method of preparation. This makes a ix tincture, from which dilutions are to be made with dispensing alcohol. See Dilutions, Homeopathic. Tincture of Tolu. (Tincture of Bal- sam of Tolu.) Tolu balsam av.oz. 3^ Alcohol, to make fl.oz. 16 Macerate the balsam in 14^2 fluid- ounces of alcohol, shaking frequently until dissolved; then filter through pa- per and wash the filter with enough alcohol to make 16 fluidounces of fil- trate.— U. S. P. The preparation of the Brit. Pharm. is one-half the strength of the above. Tincture of Tolu, Concentrated. Same as Extract, Fluid, of Tolu, which see. Tincture of Tolu, Ethereal. Tolu balsam gr. 120 Alcohol fl.oz. 1 Stronger ether fl.dr. 2 Dissolve the balsam in the alcohol by agitation, filter the solution through a pledget of cotton placed in the neck of a funnel, add the ether to the fil- trate, and mix well. This is to be used for "tolu-coating" pills. See Pill Coating. Tincture of Tolu, Soluble. Tolu balsam gr. 720 Magnesium carbonate gr. 75 Glycerin fl.oz, 6 Water, alcohol, each, to make fl.oz. 16 Mix 3 fluidounces of alcohol with the glycerin, and dissolve the balsam PHARMACEUTICAL PREPARATIONS. 507 in the mixture with the aid of heat, avoiding loss by evaporation. Next add 6 fluidounces of water, and allow the mixture to become cold. Pour off the milky liquid from the resinous precipi- tate (which latter is to be rejected), mix it with the magnesium carbonate, by trituration, and filter. Lastly, pass enough of a mixture of I volume of alcohol and 2 of water through the filter, to make the whole filtrate meas- ure 16 fluidounces. This preparation may be added to simple syrup or water without producing cloudiness. A mixture of 1 fluidounce of this preparation with 15 fluidounces of simple syrup yields- a product which may be used as syrup of tolu in all cases where the official preparation is not required. The above preparation is actually only about 10 times the strength of syrup of tolu. See also Extract, Fluid, of Tolu, Sol- uble. Tincture of Turmeric. (Tincture of Curcuma.) This is recognized by the U. S. P. only as a test preparation, the formula being as follows: Digest any convenient quantity of ground tuirneric root repeatedly with small quantities of water and throw the liquids away. Then digest the dried residue for several days with 6 times its weight of alcohol, and filter. The Brit. Pharm. directs the tincture to be made in the proportian of 1 gm. of bruised drug to 6 cc. of alcohol by maceration. For ordinary use, the tincture may be prepared by extracting 3 av.ounces of powdered drug with enough alcohol to make 16 fluidounces. Tincture of Turpentine Oil. Oil of turpentine av.oz. 1 Alcohol fl.oz. 8..fl.dr. 5 —Homeopathic. This makes a ix tincture, from which dilutions are to be made with alcohol. See Dilutions, Homeopathic. Tincture of Valerian. I. Valerian, No. 60 powder. ..av.oz. 2>Va Alcohol, water, each, to make fl.oz. 16 Prepare like tincture of black cohosh, using as a menstruum a mixture of 3 volumes of alcohol to I of water. — U. S. P. II. Valerian, cut moderately fine av.oz. 3 Water fl.oz. 3^ Alcohol fl.oz. 13 Mix, macerate for 7 days, agitating occasionally, strain with expression, and filter. — Germ. Pharm. III. Valerian, No. 40 powder. . .av.oz. 2 Alcohol, water, each, to make fl.oz. 16 Mix the alcohol and water in the pro- portion of 9 volumes of the former to 5 of the latter, macerate the drug with 12 fluidounces of this menstruum for 48 hours, agitating occasionally, then trans- fer to a percolator, and when the liquid ceases to pass add 4 fluidounces more of the mixed alcohol and water. When this has passed, subject the contents of the percolator to pressure, filter the combined liquids, and add enough of the same mixture of alcohol and water to make 16 fluidounces of product. — Brit. Form. IV. Drug (the root, recently dried) gr. 730 Distilled water fl.oz. 8 Alcohol fl.oz. 8..fl.dr. 5 — Homeopathic. This is intended to make 16 fluid- ounces. See Tinctures, Homeopathic, for method of preparation. This makes a ix tincture and is one- half the strength of the U. S. P. prep- aration. Dilutions: 2x is to be made from 1 volume of tincture, 4 of dis- tilled water, and 5 of alcohol; 3x and higher are to be made with dispensing alcohol. See Dilutions, Homeopathic. 508 STANDARD FORMULARY OF Tincture of Valerian, Ammoniated. (Compound or Volatile Tincture of Valerian.) I. Valerian, No. 60 powder, .av.oz. 3*4 Aromatic spirit of ammonia, to make fl.oz. 16 Prepare like tincture of black cohosh, using aromatic spirit of ammonia as a menstruum. — U. S. P. II. Valerian, No. 40 powder. . .av.oz. z x A Oil of nutmeg m. 25 Oil of lemon m. 15 Ammonia water fl.dr. 13 Water fl.oz. sYa Alcohol fl.oz. g]4 Mix all together, macerate for 7 days, agitating occasionally, strain with ex- pression, and filter in a well-covered funnel.— Brit. Pharm. Tincture of Valerian, Ethereal. Valerian, cut moderately ■ fine av.oz. 3 Stronger ether fl.oz. 5 Alcohol fl.oz. 13 Mix, macerate for 7 days, agitating occasionally, strain with expression ,and filter in a well-covered funnel. — Germ. Pharm. See also Tinctures, Ethereal. Tincture of Vanilla. (Extract or Es- sence of Vanilla.) Vanilla, cut into small pieces and bruised av.oz. 5 Sugar, coarse powder av.oz. 10 Alcohol, water, each, to make fl.oz. 48 Mix the alcohol and water in the pro- portion of 13 volumes of the former to 7 of the latter. Macerate the vanilla in 24 fluidounces of this mixture for 12 hours, then drain off the liquid, trans- fer the vanilla to a mortar, beat it with the sugar to a uniform powder, pack the latter into a percolator, and pour on the liquid which was drained off. When this has disappeared from the surface of the powder, gradually pour on more of the menstruum until 48 fluidounces of percolate are obtained. — N. F. Instead of cutting and bruising the vanilla, it may be more conveniently re- duced by means of a food chopper. Other formulas for this tincture as well as for other flavoring extracts may be found in the Standard Manual of Beverages. Tincture of Vanillin, Compound. (Compound Essence of Vanillin.) Vanillin gr. 45 Cumarin gr. 3 Glycerin fl.oz. 2 Simple syrup fl.oz. 2 Alcohol fl.oz. 3 Comp. tincture of cudbear, .fl.dr. 2 Water, to make fl.oz. 16 Dissolve the vanillin and cumarin in the alcohol, add the glycerin, syrup, and tincture, and lastly, enough water to make 16 fluidounces. Tincture of Veratrum. (Tincture of Veratrum Album.) Veratrum album, cut mod- erately fine av.oz. 1 1 / 2 Water fl.oz. 3^ Alcohol fl.oz. 13 Mix, macerate for 7 days, agitating occasionally, strain with expression, and filter. — Germ. Pharm. In this country the tincture of the closely allied drug, veratrum viride, is used; see Tincture of Veratrum Viride. Tincture of Veratrum Viride. (Tinc- ture of American or Green Hella- bore — Tincture of Veratri Viridis. Veratrum viride, No. 60 powder av.oz. 1^ Alcohol, to make fl.oz. 16 Prepare like tincture of cantharides. — U. S. P. This preparation is only one-fourth as strong as the corresponding prepara- tion of the U. S. P. 1890. II. Dr. Norwood's formula for this tincture is said to have been as fol- lows : Veratrum viride, dried. .. .av.oz. 8 Water fl.oz. i*/ 2 Alcohol fl.oz. 14^2 Mix, macerate for 14 days, express, and filter. PHARMACEUTICAL PREPARATIONS. 509 III. Veratrum viride, fresh root x gathered soon after decay of leaves in autumn, and sliced transversely av.oz. 8 Diluted alcohol fl.oz. 16 Mix, macerate for 14 days, agitating occasionally, express, and filter. — Ec- lectic. IV. Veratrum viride, No. 40 powder av.oz. 3%. Alcohol, to make fl.oz. 16 Extract the drug by percolation. — Brit. Form. V. Fresh drug (root), contain- ing solids gr. 730 (plant moisture, av.oz. 3.9) Alcohol fl.oz. 12^4 — Homeopathic. This is intended to make 16 fluid- ounces. See Tinctures, Homeopathic, for method of preparation. This is a ix tincture, from which di- lutions are to be made with dispensing alcohol. See Dilutions, Homeopathic. Tincture of Viburnum, Compound. (Compound. Tincture of Cramp Bark or High Cranberry — Vi- burnum Compound.) I. Cramp bark gr. 240 Wild yam gr. 240 Scullcap gr. 72 Clove gr. 360 Cinnamon gr. 480 Glycerin fl.oz. 1 Alcohol, water, each, to make fl.oz. 16 Reduce the drugs to a moderately coarse (No. 40) powder. Mix the glyc- erin with 12 fluidounces of alcohol arid moisten the powder with 2.y 2 fluidounces of this mixture, and macerate for 48 hours in a percolator. Then percolate with the remainder of this menstruum, followed by a mixture of 5 volumes of alcohol and 1 of water, until 16 fluid- ounces of tincture are obtained. — N. F. II. Cine. Acad. Pharm. uses this formula : Fluid ext. of cramp bark fl.oz. 2^ Fluid ext. of scullcap fl.dr. 6^2 Fluid extract of wild yam... fl.dr. 6^2 Fluid extract of beth root . . . fl.dr, 6 l / 2 Fluid extract of aletris (star grass -or unicorn root) fl.dr. 6y 2 Mix, allow to stand a few days, and filter. Each fluidram represents about 10 gr. of cramp bark and 3 gr. each of scull- cap, wild yam, beth root and star grass. The first formula is the preferable one. III. Cramp bark av.oz. J / 2 Lobelia seed av.oz. % Skunk cabbage seed av.oz. y, Stramonium seed gr. 55 Capsicum gr. 55 Blood-root gr. 55 Alcohol, to make fl.oz. 16 Reduce the drugs to moderately fine powder and extract by maceration or percolation. — Eclectic. If skunk cabbage seed is not avail- able, the root maybe substituted for it. This preparation is used in asthma and hysteria. A similar Eclectic prep- aration used for the same purposes, be- ing also suitable for females during gestation, is the following: Cramp bark av.oz. y 2 Scullcap av.oz. y Skunk cabbage av.oz. y, Clove gr. 55 Capsicum gr. 30 Good sherry or native wine. fl.oz. 16 The drugs are to be used in coarse powder and may be extracted by mac- eration. Tincture, Volatile. Thomsonian (from the Materia Med- ica) : To 1 quart of cherry spirits add 2 ounces of capsicum, when settled pour off, and add a few drops of oil of pennyroyal. The cherry spirits is brandy in which cherry-stone kernels have been mac- erated. Tincture of Wahoo. (Tincture of Euonymus.) Wahoo bark, powder av.oz. $y Alcohol sufficient Extract the drug by percolation so as to obtain 16 fluidounces of product, — Brit. Form. 510 STANDARD FORMULARY OF Tincture, Warburg's. See Tincture, Antiperiodic. Tincture of Water-Pepper. See Tincture of Smart Weed. Tincture of Wild Cherry. (Tincture of Virginian Prune.) Wild cherry, No. 20 powd.av.oz. 3^4 Alcohol fl.oz. 10 Distilled water fl.oz. 6 Mix the drug with the water, set aside in a closed vessel for 24 hours, then add the alcohol, macerate for 6 days more, agitating occasionally, strain with expression, and filter. — Brit. Pharm. Tincture of Wild Indigo. (Tincture of Baptisia.) Fresh drug (root bark) gr. 730 (plant moisture, av.oz. 3.9) Distilled water fl.dr. 13 Alcohol fl.oz. nJ4 — Homeopathic. This is intended to make 16 fluid- ounces. It makes a ix tincture. See Tinctures, Homeopathic, for method of preparation. Dilutions: 2x is to be made from 1 volume of tincture, 2 of distilled water, and 7 of alcohol; 3x and higher are made with dispensing alcohol. See Di- lutions, Homeopathic. Tincture of Witch-Hazel. (Tincture of Hamamelis.) Hamamelis bark, No. 20 powder gr. 730 Diluted alcohol, to make... fl.oz. 16 Extract the drug by percolation. — Brit. Form. Tincture of Wormseed. (Tincture of Cina — Tincture of German or Le- vant Wormseed — Tincture of Santonica.) Dry drug gr. 730 Alcohol fl.oz. 16 — Homeopathic. This is intended to make 16 fluid- ounces. See Tinctures, Homeopathic, for method of preparation. This makes a ix tincture, from which dilutions are made by addition of dis- pensing alcohol. See Dilutions. Homeo- pathic. Tincture of Wormwood. (Tinctuie of Absinthium.) I. Wormwood, cut moderately fine av.oz. 3 Water fl.oz. 3^ Alcohol fl.oz. 13 Mix, macerate for 7 days, agitating occasionally, strain with expression, and filter. — Germ. Pharm. II. Wormwood, coarse powder.av.oz. 1^2 Water fl.oz. 4 Alcohol .fl.oz. I2.y 2 Mix, macerate for 7 days, agitating occasionally, express, and filter. — Swed., Norw., and Dan. Pharms. Tincture of Wormwood, Compound. Blessed thistle gr. 130 Galangal gr. 130 Orange berries gr. 130 Wormwood gr. 520 Water fl.oz. 4 Alcohol fl.oz. 12^ Reduce the drugs to coarse powder, mix with the alcohol and water, mac- erate for 7 days, agitating occasionally, express, and filter. — Swed. Pharm. This is akin to the tinctura amara of the Norw. and Dan. Pharms. See Tincture, Bitter, No. IV. Tincture of Zedoary, Bitter. (Com- pound Tincture of Zedoary.) Zedoary root av.oz. 4 Aloes av.oz. 2 Rhubarb av.oz. 1 Gentian av.oz. 1 White agaric av.oz. 1 Saffron av.oz. 1 Glycerin fl.dr. 15 Alcohol, water, each, to make fl.oz. 14J/2 Reduce the solids to a - moderately coarse (No. 40) powder, moisten this with a sufficient quantity of a mixture of 2 volumes of alcohol and 1 of water, and percolate it in the usual manner, with this menstruum, until II fluid- ounces of percolate are obtained. Add to this the glycerin and set it aside. Then continue the percolation, until the drugs are practically exhausted, evap- orate the new percolate to V/z fluid- PHARMACEUTICAL PREPARATIONS, 511 ounces, and add it to the reserved por- tion. Each fluidram represents 15 gr. of zedoary, about 7 gr. of aloes, and about 3H gr. each of the other drugs. — N. F. The above preparation is not identi- cal with the Tincture of Zedoary, Com- pound (which see), which was formerly official in some continental pharmaco- peias. Tincture of Zedoary, Comp. (Carmin- ative Tincture — Wedell's Tinc- ture or Drops.) This preparation, formerly official in some continental pharmacopeias, is as follows : Zedoary, coarse powder gr. 580 Calamus, coarse powder gr. 290 Galanga, coarse powder gr. 290 Roman chamomile, cut gr. 145 Anise, bruised gr. no Clove, bruised gr. no Mace, cut gr. 75 Bitter orange peel, coarse powder gr. 40 Spirit of hydrochloric ether.fl.oz. 2 Peppermint water fl.oz. 8 Alcohol fl.oz. g]/ 2 Macerate the drugs with the mixed alcohol and water for 8 days, agitating occasionally, express, add the spirit to the colature, allow to stand for several days, and filter. — D. Tisanes. These are weak aqueous preparations, used by the French, which are made from drugs by maceration, infusion, di- gestion or decoction. Tonics. Under this name are grouped a num- ber of miscellaneous preparations which have been favorite formulas of well- known physicians. Tonic, Acid Iron, Cotton's. Ferrous sulfate, pure gr. 360 Nitrohydrochloric acid. .. .fl.oz. 2 Mix and let stand for 24 hours. The dose is 10 to 12 drops in 3 or 4 fluidounces of water. Tonic, Hammond's. This is the usually accepted formula: Strychnine sulfate gr. Yi Iron phosphate, scale gr. 60 Quinine sulfate gr. 60 Diluted phosphoric acid. .. .fl.oz. 2 Syrup of ginger, to make. . .fl.oz. 2 The strychnine sulfate and iron phos- phate should first be dissolved in a small amount of warm distilled water. Tonic, Hensel's. (Hensel's Tonicum — Essentia Tonica Henseli — Tinc- tura Tonico-Nervina Henseli — Tinctura Ferri Acetica Formicica or Acetico-Formicati.) Marble dust gr. 150 Ferrous sulfate, pure, crys- tal gr. 105 Solution of iron tersulfate, U. S. P m. 400 Acetic acid, glacial, .fl.oz. 3..m. 45 Formic acid, sp. gr. 1.20. . .fl.dr. 4 Acetic ether fl.dr. 1 Alcohol fl.oz. 5 Distilled water fl.oz. 6^ Dissolve the marble dust in the formic acid diluted with 2>Va fluidounces of the water. Dissolve the ferrous sulfate in the acetic acid mixed with the remain- der of the water and add the solution of iron tersulfate. Mix the two solu- tions, add the alcohol, filter off the pre- cipitated calcium sulfate, after the latter has subsided considerably, and then add the acetic ether. Some other strength of formic acid may be used, if it be on hand, provided more or less of it be employed and correspondingly' less or more water. If the preparation can be allowed to stand for 2 or 3 months before using, no acetic ether need be added, as it will form by interaction of the alcohol and acetic acid. The above is the older formula (re- duced from all parts by weight) ; a later and slightly different formula is the fol- lowing from the Badische Ergaenzungs Taxe (in D.) : Calcium carbonate gr. 300 Ferrous sulfate, pure, crys- tal _ gr. 105 Solution of iron tersulfate, U. S. P m. 400 Acetic acid, 36 per cent fl.oz. 2.. fl.dr. 6y 4 Formic acid, sp. gr. 1.06 (25 512 STAN DAKD FORM ULARY OF p. c. of absolute acid) fl.oz. 2. .m. 15 Acetic ether fl.dr. V/2 Alcohol fl.oz. 5 Distilled water fl.oz. zVa Mix all like the preceding, set aside in a stoppered bottle for 8 days in a cool place, and filter. Stronger acetic and formic acids may be used, if desired, provided corre- spondingly less be employed and more of water. Tonic, Red, Wood's. Nitrohydrochloric acid fl.dr. 2 Strychnine sulfate gr. 1 Syrup of ginger fl.oz. iy 2 Comp. tincture of gentian. . .fl.oz. 2 Compound tincture of carda- mom, to make - fl.oz. 6 The strychnine sulfate should be dis- solved in the acid or in a small amount of hot distilled water. Transfusion Fluids. I. Billroth's : Sodium phosphate gr. 3 Sodium carbonate gr. 20 Ammonium carbonate gr. 20 Sodium chlorid gr. 60 Alcohol m. 160 Distilled water, to make. . .fl.oz. 20 II. Little's : Sodium phosphate gr. 3 Potassium chlorid gr. 6 Sodium carbonate gr. 40 Sodium chlorid gr. 60 Distilled water, to make. ..fl.oz. 20 III. Weber's: Sodium bicarbonate gr. 6 Calcium chlorid gr. 6 Potassium chlorid „ gr. 6 Sodium chlorid gr. 480 Distilled water, to make. . .fl.oz. 8 For use, dilute 1 fluidounce of this solution with water at 50 deg. C, so as to make 16 fluidounces. Triturations. The U. S. P. gives a general process for making a class of preparations known as triturations, as follows : Weigh 1 part of the substance and 9 parts of sugar of milk in moderately fine powder, separately. Place the sub- stance, previously reduced if necessary to a moderately fine powder, in a mortar; add about an equal measure of sugar of milk, mix well by means of a spatula, and tritu- rate the powders thoroughly together. Then add fresh portions of sugar of milk, from time to time, until the whole is added, and continue the trituration until the substance is intimately mixed with all the sugar and the whole is re- duced to fine powder. These preparations are intended to be dilutions in powder form of potent me- dicinal substances. For the triturations of homeopathy, see Triturations, Homeopathic. Trituration of Calcium Sulfid. Calcium sulfid part 1 Milk sugar parts 99 Mix thoroughly by trituration. — Eclec- tic. This makes the first centesimal tritu- ration. The first decimal trituration may be made by mixing 1 part of calcium sulfid with 9 parts of milk sugar. Trituration of (Wood) Charcoal. Wood charcoal part 1 Milk sugar parts 99 Mix thoroughly by trituration. — Ec- lectic. This makes the first centesimal tritu- ration. The first decimal trituration may be made by mixing one part of wood charcoal with 9 of milk sugar. Trituration of Croton Oil. Croton oil part I Sugar of milk, powder parts 49 Ether parts 10 Dissolve the oil in the ether, mix this with about one-third of the sugar and triturate until the ether has evaporated ; then add the remainder of the sugar in divided portions, triturating thoroughly after each addition. — Eclectic. Trituration of Elaterin. Elaterin gr. 10 Sugar of milk, moderately fine powder gr. 90 Mix according to directions given un- der Triturations, which see. — U. S. P. PHARMACEUTICAL PREPARATIONS. 513 Triturations, Homeopathic. Triturations of homeopathic phar- macy are made by triturating solid sub- stances with milk sugar, preferably in- soluble solid substances, and reserving soluble substances for making dilutions (see Dilutions, Homeopathic). To make the first decimal trituration, rub together i part by weight of drug with 9 parts by weight of finely pow- dered milk sugar, and triturate until the largest drug particles do not exceed i/ioo of an inch in diameter. This rule is inapplicable to moist and soluble sub- stances, and relates chiefly to those which are hard and practically insoluble, such as metals and minerals. It will be found difficult to reach the desired reduction in any specified time, and therefore the old one-hour time limit is not to be depended upon, some sub- stances being reducible in less time, while most of the metals require more time. The trituration obtained is the first decimal trituration, which is designated as ix. The second decimal (2x) trituration is made by triturating I part by weight of the first decimal trituration with 9 parts of finely powdered milk sugar un- til the largest drug particles do not ex- ceed 1/2000 of an inch in diameter. The third decimal (3x) trituration is made from the second by rubbing with 9 times its weight of milk sugar until the largest drug particles measure not to exceed 1/4000 inch in diameter. Higher triturations are made from the next weaker trituration by incorporating with it 9 times its weight of milk sugar. Hahnemann's original method of ma- king triturations was as follows : Take 100 grains of fine milk sugar and divide it into three equal parts. Then add 1 grain of the drug to one of the three parts of milk sugar in a mortar, mix well with a spatula, then rub for 6 minutes with a moderate degree of force. The trituration is then to be scraped together during 4 minutes. An- other third of milk sugar is then added and treated exactly like the first third ; then the last third is added and treated in exactly the same manner. This pro- duces the first centesimal (1 or ic) trit- uration. The second (2 or 2c) is made from the first by trituration of the first with 100 times its weight of milk sugar, and so on for the third and succeeding triturations. The centesimal trituration is no long- er recognized by the standard homeo- pathic work, the Pharmacopeia of the American Institute of Homeopathy. Tincture triturations are a class of preparations different from the prece- ding triturations in that they are made from the strong tinctures, and conse- quently contain the soluble constituents only of the drug, and should be dis- tinguished from triturations made from the entire drug substance. In making, add 10 cc. of the strong tincture to 10 gm. of milk -sugar (or 90 minims to 85 grains), mix carefully in a mortar with pestle and spatula, and cover with a paper until the powder is very nearly dry; then triturate gently until quite dry, and preserve in glass or porcelain jars tightly closed, in a cool, dry place. Succeeding triturations are to be made by adding to each part of the next low- er trituration 9 parts of milk sugar, and triturating thoroughly. These tincture triturations are akin to medicated powders. See Medications, Homeopathic. Trituration of Iron (Ferrous) Car- bonate. A mixture of equal weights of sac- charated iron carbonate, U. S. P., and milk sugar makes the Homeopathic ix trituration. See Triturations, Homeo- pathic. Trituration of Podophyllin. Podophyllin part 1 Milk sugar parts 99 Mix thoroughly by trituration. — Ec- lectic. 514 STANDARD FORMULARY OF This forms the first centesimal tritu- ration. The first decimal trituration may be made by mixing i part of podo- phyllin with 9 parts of milk sugar. Trituration of Santonin and Podo- phyllin. Santonin gr- 5 Podophyllin gr. 1 White or milk sugar gr. 60 Mix thoroughly by trituration and di- vide into 10 powders.— Eclectic. This is an excellent remedy against intestinal worms. The dose is one pow- der night and morning. Trituration of Sepia. Sepia is used in Homeopathic ix and higher triturations. See Triturations, Homeopathic. The lower triturations require much time and labor in their preparation, as sepia is difficult to re- duce. Sepia is a brownish-black substance which is the dried inky secretion of the cuttle fish. As it appears commercially, it consists of a brittle solid mass, almost tasteless, and having a faint smell of sea fish. It breaks with a conchoidal, shining fracture. The article prepared for artists is unfit for medicinal use. Triturations, Tincture. See under Triturations, Homeopathic. Troches. (Lozenges — Tablets— Pas- tilles— Zeltchen— Trochisci.) A number of troches are recognized by the U. S. P. These consist, as a rule, of medicinal solid substances mixed with tragacanth or acacia and then made into a mass with some water or syrup, or else they are directly made into a mass by the addition of mucilage, the mass then being rolled out into sheets, and cut into lozenges by means of a suitable punch. After being cut, the lozenges should be put into a warm place to dry. The sugar used for making troches should be of the very fine kind known as "confectioners' sugar." The Brit. Pharm. recognizes four kinds of vehicles for troches, known re- spectively as "fruit vehicle," "rose ve- hicle," "simple vehicle" and "tolu ve- hicle," and for preparing the troches, the following general directions are given : Troches with Fruit Vehicle. — Take 100 times the quantity of drug ordered for one troche and mix it intimately with 3 av.ounces and 90 grains of finely powdered sugar and 60 grains of pow- dered acacia. Make the mixture into a suitable mass with 2 fluidrams of mu- cilage of acacia and 175 grains of black- currant paste previously softened with boiling distilled water, adding any addi- tional water that may be necessary to make the mass. Divide the latter into 100 equal troches, and dry them in a hot-air chamber or other warm place at a moderate temperature. The mass may be rolled out like a dough and cut with a punch. The currant paste may be the article of commerce or it may be prepared ac- cording to the directions given under Paste, Currant, which see. Troches with Rose Vehicle. — Take 10a times the quantity of drug ordered for one troche and mix it intimately with S T A av.ounces of finely powdered sugar and 60 grains of powdered acacia. Make the mixture into a suitable mass with 1 fluidram of mucilage of acacia and sufficient rose water, and divide into 100 troches in the usual manner. Dry them in a hot-air chamber or other warm place at a moderate temperature. Troches with Simple Vehicle. — These differ from the preceding only in the use of 2 instead of 1 fluidram of mu- cilage and of distilled water instead of water. Troches with Tolu Vehicle. — Take 100 times the quantity of drug ordered for one troche, dissolve what alkaloidal salts may be ordered in 35 minims of distilled water, and mix the solution in- timately with 3 av.ounces and 175 grains of finely powdered sugar and 60 grains of powdered acacia. Thoroughly in- corporate with this mixture any other PHARMACEUTICAL PREPARATIONS. 515 drugs ordered for the troches, and 35 minims of tincture of tolu. Make into a suitable mass with 2 fluidrams of mu- cilage of acacia and sufficient distilled wat»?r, and divide into 100 equal troches. Dry in a hot-air chamber or other warm place at a moderate temperature. The Germ. Pharm. states that the troches (pastilles) are to be made by compression or by massing with a suit- able excipient, and forming into troches. The 2nd Germ. Pharm. was more defi- nite, stating that the medicinal sub- stances should be mixed with sugar, made into a plastic mass with diluted alcohol and divided into troches which should weigh 15 grains. The Germ. Pharm. directs that choco- late troches are to be prepared from the drug, cocoa and sugar. The whole is to be melted at a gentle heat and al- lowed to cool partially when it is to be divided into troches weighing 15 grains each, unless otherwise specified. The older Germ. Pharm. stated that equal parts of cocoa and sugar are to be used. In making sugar troches, confectioners have other ways of preparing them be- sides those given above. It is probable that they use little or no acacia or trag- acanth but rely mainly on syrupy glu- cose as a binding agent. For another form of troches, see Pas- tilles, Glyco-Gelatin, which are prepared from gelatin and glycerin. The pastilles of the former Germ. Pharm. were different from the troches. They are directed to be prepared by mixing the ingredients in powder form, binding these with excipients and form- ing into pastilles. Water is to be used as an excipient for mixtures containing sugar, acacia or tragacanth, and alcohol for effervescent mixtures. Each pastille is to weigh 15 grains unless otherwise directed. Troches of Ammonium Chlorid. Ammonium chlorid, fine pow- der gr. 150 Extract of licorice, fine pow- 33 der gr. 300 Tragacanth, fine powder gr. 30 Sugar, fine powder gr. 600 Syrup of tolu, to make a mass Triturate the powders together until they are thoroughly mixed, add the syrup, make a mass, and divide into 100 troches.— U. S. P. Troches, Benzoic Acid. Each troche is to contain Yz grain of benzoic acid, which is to be massed with the fruit vehicle. See under heading Troches for method of preparation. — Brit. Pharm. Troches, Bismuth, Compound. Each troche is to contain Bismuth subcarbonate gr. 2 Magnesium carbonate, heavy.. gr. 2 Calcium carbonate, precipita- ted gr. 4 These substances are to be massed with the "rose vehicle." See under heading Troches for method of prepara- tion. — Brit. Pharm. Troches of Capsicum. Each troche is to contain Capsicum gr. 1 Sugar gr. 12 Mucilage of tragacanth, to make .^ a mass — Eclectic. Troches of Capsicum and Lobelia. Each troche is to contain Capsicum gr. 1 Oil of lobelia m. 1/10 Sugar gr. 12 Mucilage of tragacanth, to make a mass — Eclectic. Troches, Carbolic Acid. (Phenol Troches.) Each troche is to contain 1 grain of carbolic acid, which is to be massed with the "tolu vehicle." See under head- ing Troches for method of preparation. — Brit. Pharm. Troches of Catchu. These have been replaced in the U. S. P. by troches of gambir. The troches of the Brit. Pharm. are made to contain each 1 gr. of catechu, which is to be massed with the "simple 516 STANDARD FORMULARY OF vehicle." See under heading Troches for method of preparation. Troches of Charcoal. Wood charcoal oz. x /z Tragacanth dr. y 2 Sugar oz. 6 Vanillin gr. 3 Water, q. s. Triturate the vanillin with 2 ounces of sugar, add the remainder of the ingre- dients and make 50 troches in the usual way. — N. F. Troches of Croton Oil. (Trochisci Crotonis.) Croton oil m. 5 Starch gr. 20 Sugar gr. 6o Chocolate gr. 120 Water sufficient Make into 30 troches. — Eclectic. Troches of Cubeb. I. Oleoresin of cubeb gr. 3° Oil of sassafras gr. 15 Acacia, fine powder gr. 185 Ext. of licorice, fine powder.gr. 385 Syrup of tolu, to make a mass Rub the two powders together until well mixed, then add the oleoresin and oil, and incorporate them thoroughly; lastly, add the syrup, make a mass, and divide it into 100 troches. — U. S. P. II. This is an example of the troches of the London Throat Hospital: Cubeb, fine powder gr. 60 Extract of licorice gr. 350 Tragacanth, powder gr. 20 Sugar, fine powder gr. 60 Black-currant paste. Water, each sufficient Divide into 100 troches. Troches, Eucalyptus Gum. (Red Gum Troches.) Each troche is to contain 1 grain of eucalyptus gum, which is to be massed with the "fruit vehicle.''— Brit. Pharm. See under heading Troches for meth- od of preparation. The eucalyptus gum is the so-called "red gum" from the bark of Eucalptus rostrata and some other species of Eu- calyptus, and is imported from Aus- tralia. Troches of Gambir. (To Replace Troches of Catechu, U. S. P. 1890.) Gambir, fine powder gr. 90 Tragacanth, fine powder gr. 30 Sugar, fine powder av.oz. 2% Stronger orange flower wa- ter, to make a mass Rub the powders together until well mixed, then add the orange flower wa- ter enough to form a mass, which is to be divided into 100 troches. — N. F. Troches of Ginger. Tincture of ginger m. 325 Tragacanth, fine powder gr. 60 Sugar, fine powder av.oz. 4 l / 2 Syrup of ginger, to make... a mass Mix the tincture with the sugar, ex- pose the mixture to the air until dry, then add the tragacanth, mix well, add the syrup, and divide the mass into 100 troches. Troches, Guaica Resin. Each troche is to contain 3 grains of guaiac resin, which is to be massed with the "fruit vehicle." — Brit. Pharm. See under heading Troches for meth- od of preparation. Troches of Ipecac. I. Ipecac, No. 60 powder gr. 30 Tragacanth, fine powder gr. 30 Sugar, fine powder av.oz. 2*4 Syrup of orange, to make... a mass Rub the powders together until well mixed, add the syrup, and divide the mass into 100 troches. II. The Brit. Pharm. troche contains %■ grain of powdered ipecac, which is to be massed with the "fruit vehicle." See under heading Troches for method of preparation. III. Ipecac, fine powder gr. 15 Elecampane, fine powder, .av.oz. z /i Sugar, fine powder av.oz. 2^ Oil of anise m. 8 Mucilage of tragacanth, to form a mass — Eclectic. PHARMACEUTICAL PREPARATIONS. 517 Divide into troches weighing 10 or 12 grains each. Troches, Ipecac and Morphine. See Troches, Morphine and Ipecac. Troches of Iron. Iron (ferric) hydrate, dried at a temperature not ex- ceeding 80 deg. C gr. 450 Vanilla, cut into slices gr. 15 -s Sugar, fine powder av.oz. 3^ Mucilage of tragacanth, to make a mass Triturate the vanilla, first, with a por- tion of the sugar to a uniform powder, and afterwards with the ferric hydrate and the remainder of the sugar, until well mixed. Then add the mucilage, and _divide the mass into 100 troches. See also Troches, Iron, Reduced. Troches, Iron, Reduced. The . Brit. Pharm. troche contains 1 grain of reduced iron, which is to be massed with the "simple vehicle." See under heading Troches for method of preparation. See also Troches of Iron for another kind of iron troche. Troches of Licorice, Compound. Ammonium chlorid gr. 30 Morphine hydrochlorid ....gr. 2 Acacia gr. 140 Sugar gr. 140 Extract of licorice. gr. 140 Oil of sassafras m. 10 Oil of stiliingia m. 7 Tincture of tolu fl.dr. 1 Water sufficient Reduce all the solids to very fine powder, add the oils and tincture, mix well, add enough water to make a mass, and divide into 60 troches. — Eclectic. Troches of Licorice and Opium. Extract of licorice, fine pow- der gr. 225 Opium, powdered gr. 7^ Acacia, fine powder gr. 180 Sugar, fine powder gr. 300 Oil of anise m. 3 (about drops 4) Water, to make a mass Triturate the powders together inti- mately until well mixed, then incor porate the oil, add the water, and divide the mass into 100 troches. See also Troches, Opium, which are similar to the above. Troches of Magnesia. I. Magnesia, light gr. 300 Nutmeg, fine powder gr. 15 Sugar, fine powder gr. 900 Mucilage of tragacanth sufficient Rub the magnesia and the powders together until they are thoroughly mixed; then with mucilage form a mass, to be divided into 100 troches. II. Magnesia gr, 120 Sugar, powder gr. 640 Ginger, powder gr. 5 J / 2 Mucilage of tragacanth sufficient Divide into troches weighing 8 or 10 grains each. — Eclectic. Troches, Morphine. The Brit. Pharm. troche contains 1/36 grain of morphine hydrochlorid, which is to be massed with the "tolu vehicle." See under heading Troches for method of preparation. Troches of Morphine and Ipecac. I. Morphine sulfate gr. 2Y2 Ipecac, No. 60 powder gr. 8 Oil of wintergreen m. 3 (about drops 4) Sugar, fine powder av.oz. 2^4 Mucilage of tragacanth, to make a mass Rub the powders together until they are thoroughly mixed, incorporate the oil, add the mucilage, and divide the mass into 100 troches. II. Morphine hydrochlorid gr. 1/36 Ipecac, fine powder gr. 1/12 Mass with "tolu vehicle." See under heading Troches for method of prep- aration. — Brit. Pharm. 518 STANDARD FORMULARY OF Troches, Opium. Extract of opium gr. io Tincture of tolu m. 30 Acacia, powder gr. 120 Extract of licorice gr. 365 Sugar, fine powder. .av.oz. 2..gr. 100 Distilled water sufficient Add the extract of opium, first soft- ened by means of a small amount of water, and the tincture of tolu, to the extract of licorice, which has been heat- ed on a water bath. When the mixture is reduced to a proper consistence, re- move it to a slab, add the sugar and acacia, previously rubbed together, mix the whole thoroughly, and make a mass with distilled water. Divide this into 100 troches and dry these in a hot-air chamber or other warm place at a mod- erate temperature.— Brit. Pharm. 1885. See Troches of Licorice and Opium, which are similar to the above. Troches of Peppermint. Oil of peppermint m. 15 Sugar, fine powder av.oz. 2^/4 Mucilage of tragacanth, to form a mass Rub the oil and sugar together until well mixed, add the mucilage, and di- vide the mass into 100 troches.— N. F. Troches of Phenolphthalein. Phenolphthalein gr. 50 Acacia gr. 80 Sugar oz. \ l / 2 Vanillin gr. 3 Carmine gr. 1 Water, q. s. Triturate the carmine and vanillin with a quarter of the sugar, then add the other ingredients and make 50 troches in the usual way. — N. F. Troches of Potassium Chlorate. I. Potassium chlorate, fine powder gr. 225 Tragacanth, fine powder gr. 45 Sugar, fine powder gr. 450 Water, to make a mass Mix the sugar with the tragacanth by trituration in a mortar, then transfer j Pharm. the mixture to a sheet of paper, and by means of a bone or horn spatula mix it with the potassium chlorate, being care- ful, by avoiding trituration or pressure, to prevent the mixture from igniting or exploding. Lastly add the water, and divide the mass into 100 troches. — U. S. P. These are one-half the size and strength of the troches of the U. S. P. 1890. Troches of Quinine Tannate. These troches contain 1 grain of qui- nine tannate each. Troches, Red Gum. See Troches, Eucalyptus Gum. Troches of Rhatany. (Troches of Krameria.) I. Extract of rhatany gr. 90 Tragacanth, fine powder gr. 30 Sugar, fine powder av.oz. 2^4 Stronger orange flower wa- ter, to make a mass Rub the powders and extract together until reduced to a fine, uniform pow- der, add the water, and divide the mass into 100 troches. II. The Brit. Pharm. troche contains 1 grain of extract of rhatany, which is to be massed with the "fruit vehicle." See under heading Trpches for method of preparation. III. The following is the formula of the London Throat Hospital : Extract of rhatany, powder, .gr. 300 Tragacanth, powder gr. 20 Sugar, fine powder gr. 80 Red-currant paste, to make.. a mass Divide into 100 troches. Troches, Rhatany and Cocaine. Extract of rhatany gr. 1 Cocaine hydrochlorid gr. 1/20 Make a mass with the "fruit vehicle" according to directions given under heading Troches, which see. — Brit. PHARMACEUTICAL PREPARATIONS. 519 Troches of Rhubarb and Potassa. Rhubarb .gr. 90 Potassium bicarbonate gr. 45 Oil of peppermint m. 6 Sugar gr. 525 Mucilage of tragacanth sufficient Reduce the solids to powder, add the oil and enough mucilage to make a mass, and divide into 50 troches. — Eclectic. Troches of Santonin. I. Santonin, fine powder gr. 50 Tragacanth, fine powder gr. 45 Sugar, fine powder av.oz. 3 Stronger orange flower water, to make a mass. Rub the powders together until well mixed, then add the water, and divide the mass into 100 troches. — N. F. Keep the troches in dark, amber-col- ored bottles. In the Compound Santonin Troche, N. F., V-2. gr- calomel is added. II. The Brit. Pharm. troche con- tains 1 grain of santonin which is to be massed with the "fruit vehicle." See under heading Troches for method of preparation. III. The Germ. Pharm. states that each troche is to contain }i gr. of drug. Troches of Santonin, Compound. Santonin gr. 25 Resin of jalap gr. 10 Acacia gr. 30 Chocolate, pure gr. 60 Sugar gr. 160 Water sufficient Mix well, incorporate some water, make a mass, and divide into 64 troches or pills, which may be coated with sugar. Gamboge or podophyllin may be sub- stituted for the jalap resin. — Eclectic. These are useful as a vermifuge. For a child from 3 to 6 years of age 2 to 4 may be used daily as long as required. Troches of Sodium Bicarbonate. I. Sodium bicarbonate gr. 270 Nutmeg, bruised gr. 15 Sugar, fine powder. av.oz. 1, gr. 370 Mucilage of tragacanth, to make a mass. Triturate the nutmeg with the sugar, gradually added, until reduced to fine powder, and mix this intimately with the sodium bicarbonate; then add the mucilage, and divide the mass into 100 troches.— U. S. P. II. The Brit. Pharm. troche con- tains 3 grains of sodium bicarbonate, which is to be massed with the "rose vehicle." See under heading Troches for method of preparation. III. Sodium bicarbonate gr. 165 Ginger, powder gr. 8 Sugar, fine powder av.oz. 2 Mucilage of tragacanth. .. .sufficient Divide into troches weighing 10 or 12 grains each. — Eclectic. Troches of Sodium Santoninate. Sodium santoninate, fine powder gr. 50 Sugar, fine powder av.oz. 2% Tragacanth, fine powder gr. 30 Orange flower water sufficient Rub the powders together until they are thoroughly mixed, then, with orange flower water, form a mass, to be divided into 50 troches. Troches of sodium santoninate should be kept in dark amber-colored vials. Troches of Stillingia, Compound. Oil of stillingia m. 6 Oil of prickly-ash berries m. 24 Oil of sassafras m. 24 Sugar av.oz. 1 Mucilage of tragacanth sufficient Mix the oils with the sugar, add the mucilage, form a suitable mass, and divide into 48 lozenges. — Eclectic. Troches, Sulfur. Sulfur, precipitated gr. 500 Potassium bitartrate, pow- der gr. 100 Acacia, powder gr. 100 Sugar, fine powder gr. 800 Tincture of orange, Brit. Pharm m. 100 Mucilage of acacia m. 100 Mix the tincture with the powders, add the mucilage and form a mass. Di- vide into 100 troches and dry these in a hot-air chamber or other warm place 520 STANDARD FORMULARY OF at a moderate temperature. — Brit. Pharm. Troches of Tannic Acid. (Tannin Troches.) I. Tannic acid gr. 90 Tragacanth, fine powder gr. 30 Sugar, fine powder av.oz. 2}4 Stronger orange flower wa- ter, to make a mass Rub the powders together until thor- oughly mixed, then gradually add the water, and divide the mass into 100 troches.— U. S. P. Troches of Elm. These troches contain 3 grains elm, each. The mass is made with sugar, tragacanth and water, and flavored with oil wintergreen. Troches of Sulphur and Cream Tartar. These troches contain approximately 5 grains washed sulphur and 1 grain cream tartar, each. Turpentine Venice, Factitious. Gum turpentine av.oz. 10 White resin av.oz. 3 Oil of turpentine fl.oz. 10 Melt the resin, add the turpentine, al- low it to melt, then add the oil, and strain. Vapors. See Inhalations. Varnishes, Skin or Dermatic. Unna has recommended the following dermatic varnishes, which are intended to form a smooth, adherent, artificial skin, that may be medicated by various substances. These, have been worked out with the assistance of Beiersdorf. Some of these varnishes are aqueous in character, others are alcoholic. Bassorin Varnish. Unna recommends bassorin as a basis for these varnishes, which is to be ob- tained from tragacanth. 2*4 av. ounces of powdered gum are to be rubbed with water to a thin magma, and the mix- ture filtered through a filter heated by steam which retains cellulose, etc., and permits the mucilage to pass through. The latter is then evaporated so as to weigh 15 av.ounces, and finally mixed with glycerin. The same kind of varnish may also be obtained from salep. 384 grains of this, in very fine powder, triturated with 16 fluidounces of cold water to a smooth mixture, and then heated for half an hour in a steam bath, yield a preparation similar to the preceding. Glycerin should be added to this like- wise. Both of these bassorin varnishes form admirable vehicles for zinc oxid. Casein Varnish. The casein required for these prep- arations may be obtained in the follow- ing manner : Milk deprived of fat (skim-milk) is warmed at a temperature of 35 to 40 deg. C. with a small amount of rennet or rennet essence until it coagulates, and is then placed on a strainer. The coagulated mass is washed, first with common, then with distilled, water, un- til the washings no longer have an acid reaction, finally dried and reduced to powder. This powder has a yellowish- white color, is quite hard, feeling like sand, insoluble in water, but soluble in all alkaline liquids, forming a limpid liquid. Glacial acetic acid as well as lactic acid causes it to swell. The alka- line solutions, though they pass when highly diluted completely through filter paper, are not clear, but milky. The best alkali for dissolving the casein is borax. The largest proportion of borax which can be added without crystallizing out is stated to be I part for every 1 part of casein and 25 parts of water. But casein is dissolved in presence of much smaller quantities of borax. The best varnish was obtained by using the following proportions: Casein, dried as above. .. .av.oz. 3 Borax gr. 160 Water fl.oz. 14^ This solution dries rapidly and yields PHARMACEUTICAL PREPARATIONS. 521 a handsome, homogeneous, firm coating, very suitable for holding such medicinal agents as resorcin, pyrogallic acid, chrysarobin, etc. It has one drawback, namely, that it does, not long hold substances like zinc oxid, bismuth salts, white precipi- tate, etc., in suspension, and that by their precipitation the adhesiveness of the varnish is injured. This was found to be particularly the case with zinc oxid. Beiersdorf, however, ascertained that this may be prevented by glycerin. Ca- sein is retained by glycerin in form of emulsion, if it has previously been dis- solved in ammonia and the latter has been allowed to evaporate completely. This does not injure the adhesive prop- erty of the casein. The mode of pro- cedure is as follows: Casein .- av.oz. I Ammonia water, strongest (28 p. c.) av.oz. 3 or y/ 2 Glycerin av.oz. 1 Water, boiling sufficient Dissolve the casein, in the cold, in the ammonia water, add the glycerin, and apply a gentle heat until the ammonia is all dissipated. Then dissolve the residual mass in twice its weight of boiling water on a bath. This Glycerin-Casein Varnish is very elastic, dries well, forms an excellent coating, and can be combined with a great variety of remedies. Zinc oxid does not separate so quickly from it. All of the before-mentioned varnishes, after being applied to the skin, may be easily removed by washing with water — most easily the last-mentioned one. Alcoholic Balsam and Resin Varnishes. 1. Amber Varnish, for which the or- dinary or commercial amber varnish may be used after diluting it if neces- sary with alcohol to suitable consist- ence; or it may be prepared by dissolv- ing amber in a mixture of alcohol and oil of turpentine. It must not be used for zinc oxid, but is very suitable for chrysarobin and pyrogallic acid. 2. Castor Oil and Shellac Varnish, prepared from 5 av.ounces of shellac, 1 av.ounce of castor oil, and 17^2 fluid- ounces of alcohol. 3. Balsam Fir and Collodion Varnish, prepared from 1 part by weight of bal- sam of fir and 16 parts of collodion. This is excellent for chrysarobin, not so good for pyrogallic acid, very poor for mercuric oxid. 4. Castor Oil and Collodion Varnish, prepared from 1 part by weight of cas- tor oil and 8 parts of collodion. This is very good for zinc oxid, as it may be made to hold one-ninth its weight of this compound. 5. Lead Rccinoleate Varnish, pre- pared by heating 1 part by weight of lead oxid with V/t parts of castor oil until saponified, lead ricinoleate beings formed. This is then almost entirely dissolved upon the addition of 2 parts by weight of absolute alcohol. Large quantities of zinc oxid may be incor- porated with this varnish. The following examples are given, to show how these varnishes may be combined with various remedies : Ichthyol-Casein Varnish : Sodium-ichthyol part 1 Borax-casein varnish parts 3 Sulfur-Casein Varnish: Sulfur^ part 1 Glycerin-casein varnish. .... .parts 3 Zinc Oxid-Salep-Bassorin Varnish: Zinc oxid part 1 Salep-bassorin varnish parts 9 Zinc-Ichthyol-Tragacanth-Bassorin Var- nish : Zinc oxid parts 2 Sodium-ichthyol part 1 Tragacanth-bassorin varnish. parts 17 Chrysarobin Amber Varnish: Chrysarobin part 1 Amber varnish, commercial.parts 20 Pyrogallol-Shellac Varnish : Pyrogallic acid part 1 Shellac parts 5 Castor oil part 1 Absolute alcohol ._._-, parte 15 STANDARD FORMULARY OF Salicylic Acid Collodion Varnish: Salicylic acid parts 3 Balsam of fir part 1 Collodion parts 16 Zinc Oxid Collodion Varnish : Zinc oxid part 1 Castor oil part 1 Cololdion parts 8 Zinc and Lead Ricinoleate Varnish: Zinc oxid ». parts 8 Lead ricinoleate (as above) .parts 4 Absolute alcohol parts 8 One part each of collodion and stronger ether may be added to this to promote rapid drying. All parts above are by weight. Vinegars (Aceta). These are preparations made by ex- tracting drugs with diluted acetic acid, the preparations of the U. S. P. repre- senting 10 per cent, of drug. Vinegar of Bloodroot. Bloodroot, No. 30 powder. av.oz. i l / 2 Diluted acetic acid, to make.fl.oz. 14^ Moisten the drug with 6 fluidrams of the acid, pack it firmly in a conical glass percolator, and gradually pour on dilu- ted acetic acid until 16 fluidounces of percolate are obtained. Vinegar of Cantharides. Cantharides, bruised av.oz. 1^4 Glacial acetic acid, Distilled water, each, to make fl.oz. 16 Mix the acid and water in equal vol- umes, macerate the drug with 14^2 fluid- ounces of this mixture for 24 hours, and transfer to a percolator. When the liquid ceases to pass, pour on enough of the same menstruum to make 16 fluid- ounces of product. — Brit. Pharm. Vinegar of Colchicum. Colchicum root, moderately fine powder gr. 480 Diluted acetic acid, to make. fl.oz. 16 Extract the drug bv percolation. — U. S. P. i860. Vinegar of Ipecac. Fluid extract of ipecafc, of the Brit. Pharm fl.dr. 6 l / z Alcohol fl.dr. 13 Water fl.oz. 4 Diluted acetic acid, to make.fl.oz. 16 Mix, filter, and if necessary add enough diluted acetic acid to make 16 fluidounces of filtrate. — Brit. Pharm. Vinegar of Lobelia. I. The N. F. Appendix and U. S. P. 1880 preparation is prepared like vine- gar of bloodroot. II. Lobelia seed, powder av.oz. 2 Diluted acetic acid fl.oz. 16 Alcohol or concentrated acet- ic acid fl.oz. 4 Mix the drug with the diluted acetic acid, macerate for 7 days, agitating oc- casionally, express, and filter. To the filtrate add the alcohol or concentrated acid, and then enough diluted acetic acid to make 16 fluidounces. — Eclectic. Vinegar of Opium. (Black Drop- Lancaster or Quaker Black Drop.) Opium, powder gr. 730 Nutmeg, No. 30 powder, .av.oz. y 2 Sugar av.oz. 2..gr. 150 Diluted acetic acid, to make fl.oz. 16 Macerate the opium and nutmeg in 8 fluidounces of acid for 7 days, agita- ting frequently, strain with expression through muslin of close texture, and express the liquid. Mix the residue with s x A fluidounces of acid to a uni- form magma, express again as before. Mix the two liquids, filter, dissolve the sugar in the filtrate by agitation, and add enough acid through the filter to make the filtrate measure 16 fluid- ounces. — N. F. Vinegar of Squill. I. Squill. No. 20 powder av.oz. 1^4 Diluted acetic acid, to make.fl.oz. 16 Macerate the squill with 14^ fluid- ounces of acid for 7 days, agitating fre- quently, strain with expression through muslin, wash the mass on the strainer with enough diluted acetic acid to make PHARMACEUTICAL PREPARATIONS. 523 the total colature measure nearly 16 fluid- ounces. Heat this liquid to boiling, fil- ter while hot, and when cooled add enough diluted acetic acid to make 16 fluidounces. — U. S. P. II. Squill, bruised av.oz. 2. .gr. 35 Diluted acetic acid, Brit. Pharm fl.oz. 16 or sufficient Mix the drug and acid, macerate for 7 days, agitating occasionally, strain with expression, and filter. The product should measure 16 fluidounces. — Brit. Pharm. The diluted acetic acid of the Brit. Pharm. may be made by mixing n^ fluidounces of U. S. P. diluted acetic acid with 4^ of water or by mixing 15 fluidrams of U. S. P. or 36 per cent, acetic acid with enough water to make 16 fluidounces. III. Squill, cut av.oz. ift Alcohol fl.oz. 2 Acetic acid, 36 p. c fl.oz. 2]/ 2 Distilled water fl.oz. i2 l / 2 Mix all, macerate in a bottle for 3 days, agitating frequently, then strain without much expression, and filter the liquid after 24 hours. — Germ. Pharm. Vinegar, White Wine, Imitation. The following makes a good imita- tion of white wine : Acetic acid fl.oz. 16 Tartaric acid av.oz. 1 Acetic ether fl.dr. 4 White wine fl.oz. 16 Water fl.oz. 32 Washes. See Lotions. Water (Aqua). The U. S. P. VIII defined "aqua" as "potable water in its purest obtainable state" and describes it as "a colorless, limpid liquid, without odor or taste at ordinary temperatures, and odorless when heated." It should be perfectly neutral to litmus paper and must be free from metallic impurities and not possess more than the "limit" of am- monia, soluble salts, sulfates, chlorids, nitrates and organic or other oxidizable matters, which "limits" are determined by certain chemical tests. Obviously therefore not every natural or even potable water is suitable for pharmaceutical purposes, and when the matter is studied closely it will be found that but few, if any, natural waters are suitable. All natural waters contain im- purities, the latter being sometimes so abundant as to preclude the use of the water for any purpose, pharmaceutical or domestic, until it has undergone some form of purification. The question of a pure water supply is almost always an urgent as well as vital one, especially to densely populated cities. The impurities of natural water are mineral and organic, the former inclu- ding various salts, such as chlorids, sul- fates, nitrates and phosphates, the latter free and albuminoid ammonia, other sewage contaminations, and germs. Of these, the germs, including among them those causing typhoid fever, cholera, diphtheria, and other infectious diseases, are the only really dangerous or fatal ones, the other impurities being danger- ous only in so far as they furnish pabu- lum for the germs. The harmfulness Dr harmlessness of the impurities present in water can not be judged by the pres- ence or lack of odor, taste, clearness, etc., as a bad-smelling, bad-tasting, tur- bid water may be practically harmless, whereas a clear, odorless, and tasteless water may be reeking with germs. Natural water may be purified in va- rious ways as by subsidence, by filtra- tion, by boiling, by precipitation or by distillation. 1. Subsidence. — Some waters may be purified, partially at least, by allowing the water to stand until solid matter has subsided, when the clear liquid may be decanted and used. This method is practical only for waters containing large quantities of mud or clay; it would not suffice to remove germs. 2. Filtration. — The filtration referred to is through one of the numerous charcoal or earthenware filters of the 524 STANDARD FORMULARY OF market. It is true that water filtered through such an apparatus is of unusual clearness and brightness, but this should not be considered a guaranty of free- dom from impurities, either organic or mineral. The filter merely intercepts the larger particles of suspended matter but permits the smaller particles, in- cluding the germs to pass through. Water filtered in this manner therefore contains practically all the original min- eral and organic impurities. It is true that the first portions of water which have passed may be deprived of some of the organisms, but, unless the interior of the filter is thoroughly cleansed, this very stoppage of germs and a portion of other organic matter will cause a rapid multiplication of germs with the result that the filtered water will be even more tainted than the unfiltered water. 3. Boiling. — This method of purifica- tion is the best one mentioned so far, provided the boiling has been continued sufficiently long. Boiling effects several changes in water; it expels gases; it causes precipitation of the calcium car- bonate if this has been held in solution by carbonic acid gas ; and it will cause destruction of all germs. A well-boiled water (if boiled for about 5 to 10 min- utes) is therefore perfectly safe for do- mestic purposes, but may not be satis- factory for pharmaceutical or chemical purposes. After boiling and cooling, the water should be filtered, either through paper or an eahthenware filter. 4. Precipitation. — The simplest, old- est and best known method of purifica- tion of water by precipitation is by means of alum ; 15 to 30 grains of alum are to be added to a gallon of water, agitating until the salt is dissolved, then setting aside. The amount of alum to be used depends on the degree of im- purity of the water, very impure waters requiring more alum than those less im- pure. After standing for some time (from 15 minutes to several hours, al- though over night is better), depending also on the degree of impurity, the clear water may be decanted from the sedi- ment or it may be filtered. Instead of adding alum itself to the water, a ready-prepared solution of alum, about 1 av.ounce to 1 pint, may be used instead. This is said to make a quite pure water almost free from germs, but whether absolutely free from the latter is still a question. Instead of the alum, nascent calcium sulfate may be used, as follows: Add 60 grains of precipitated chalk to a gallon of water, agitate, then add 6 l / 2 fluidrams of diluted sulfuric acid, agi- tate, set aside for 12 or 24 hours, and then use the clear liquid. Keletzinsky's (Vienna, Austr.) meth- od of purification of water has been highly recommended. It is as follows: Aluminum phosphate part 1 Ferrous phosphate parts 2 Magnesium phosphate parts 2 Phosphoric acid, Distilled water, each sufficient Mix the acid and water in the pro- portion of 1 part of 85 p. c. acid with 4 parts of water or 1 part of 50 p. c. acid with 2 parts of water. The freshly prepared phosphates of aluminum, iron and magnesium are to be dissolved in sufficient of a mixture of the phosphoric acid and water, solution being aided by a gentle heat. This solution should be filtered through paper. When finished the solution can be kept on hand for any length of time. When required as a purifying agent for water, the solution is to be added in small quantities at a time to the water until no further cloudiness is produced; let the mixture stand to allow the pre- cipitate to subside, and use the clear water. The mixture acts thus: The lime salts usually contained in water will abstract from the phosphates of alu- minum, iron and magnesium a portion of the phosphoric acid to form calcium phosphate, and the compounds now PHARMACEUTICAL PREPARATIONS. 525 formed will be at once thrown out of solution. The magnesium will absorb all the free ammonia, the ferrous oxid will combine with the sulphuretted hy- drogen and other gases of decomposi- tion, while the alumina and calcium phosphate will carry the suspended par- ticles of impurity with them. A slight excess of the phosphatic solution is in no way objectionable. Hager uses this so-called "tincture of tannin" to make impure water potable : Tannic acid gr. 120 Sugar gr. 60 Distilled water fl.dr. 3 Alcohol fl.dr. 6 Mix and dissolve. Use 10, 15 or 20 drops to a glassful of water. A method which has been recom- mended of purifying water with bromin is as follows: Bromin gr. 90 Potassium bromid gr. 90 Distilled water, to make fl.oz 1 Mix and dissolve. Add 12 drops of this solution to 1 gallon of water, shake, and after 5 minutes, add 12 drops of 10 p. c. am- monia water. When the water is very impure and strongly calcareous, so much bromin solution should be used as will impart a yellowish tint to the water which will persist for one-half minute. The product is a limpid, tasteless liquid, practically free from germs. A method of purification of water which has been recommended when the water is intended for making hypoder- mic solutions and which is said to make a product even superior to that pre- pared by distillation, is as follows: Treat one gallon of boiled water with small portions, at a time, of potassium permanganate solution (1 gr. to 8 fl.oz.) until after .standing for an hour it re- tains its pink color. Then add 5 grains of alum, shake until the pink color dis- appears, and filter three times through iouble filters which have previously been scalded to render them sterile. The process should be conducted in well-closed glass containers. 5. Distillation. — Distilled water is the only water really suitable for phar- maceutical and chemical purposes, but still not all distilled water is 'good water. In selecting the apparatus, there is considerable choice. There are many distilling apparatuses on the market, and anyone may also arrange his own distilling apparatus by connecting a ves- sel suitable for a still with a condenser, preferably using a Liebig condenser. No continuous process of distillation should be used but the U. S. P. method should strictly be followed, viz.: Water volumes 1000 To make volumes 800 Distil the water from a suitable ap- paratus provided with a block-tin or glass condenser. Collect the first 100 volumes, and throw this portion away. Then collect 800 volumes and keep the distilled water in glass-stoppered bottles which have been rinsed with hot dis- tilled water immediately before being filled. The still is then to be cleansed and refilled if more distilled water is de- sired, the process of distillation being conducted as before. The first 100 volumes contain the volatile gases, including the free am- monia ; the remaining 100 volumes con- tain the solid matter. A fairly pure natural water should be used for making distilled water. Distilled water, no matter how care- fully prepared, may have a peculiar dis- agreeable odor and taste. This may be due to the use of a tin distilling appara- tus, to the use of rubber connections, or to the use of the distilling apparatus for distilling all kinds of substances. Only glass, block tin or heavy tinned copper distilling apparatus should be used, rubber connections should be avoided as much as possible, and the still should be reserved for the making of distilled water only. 526 STANDARD FORMULARY OF Even with the utmost care, distilled water is not absolutely pure water. Dis- tilled water may be further purified by adding to it enough potassium perman- ganate to imoart a pink tinge, then making it alkaline with caustic potash, and then heating in an open vessel until about 1/20 of the water has evaporated, when all the ammonia will have been dissipated ; the remaining water is then to be redistilled. If the water still con- tains ammonia add enough potassium or sodium acid sulfate to "fix" the latter, and redistil. Waters. (Medicated Waters.) The U. S. P. states that the medi- cated waters, when prepared from vola- tile oils are intended to be, as nearly as practicable, saturated solutions which must be clear, and free from solid im- purities. In the processes which follow, the solution of the volatile oils is facili- tated by the use of purified talc (the U. S. P. 1890 directed precipitated cal- cium phosphate) ; but the solution may, if preferred, be aided by replacing the talc by pulped or shredded filter paper; waters may also be made by the addi- tion of volatile oils to hot water and separation of the excess of the former, or by distillation of the drug or vola- tile oil with water, if by either of these methods the finished product corres- ponds in all respects with official re- quirements. Water, Acorn, Rademacher's. (Aqua Glandium — Aqua Quercus — Aqua Quercus Glandium.) Acorns, deprived of the hard outer hulls, coarse powder av.oz. io^4 Alcohol fl.oz. 3 Water sufficient Mix and then distil on a water bath so as to obtain 15^2 av.ounces of dis- tillate.— H. Water, Anise. Oil of anise m. i£ Purified talc gr. 115 Distilled water, to make.. fl.oz. 16 Triturate the oil with the talc, add the water gradually with continued trit- uration, filter, and pass the filtrate through the filter repeatedly until the water is clear.— U. S. P. In the Brit. Pharm. it is directed to mix 6^4 av.ounces of anise with one gallon of water and to distil one-half gallon from this. Water, Aromatic. (Wind Wasser — Kinder or Mutter Balsam.) This may be conveniently prepared as follows : Oil of fennel drops 7 Oil of lavender flowers. . .drops 7 Oil of mace drops 7 Oil of peppermint drops 7 Oil of rosemary drops 7 Oil of ginger drops 7 Oil of sage drops 7 Oil of clove drops 14 Oil of cassia drops 14 Oil of lemon drops 14 Alcohol fl.oz. io l A Water fl.oz. $y 2 Mix the oils with the alcohol, add the water, let stand 3 days, agitating occa- sionally, then filter clear. — H. Waters, Aromatic, Concentrated. The so-called "concentrated aromatic waters," more common in Germany than here, are merely alcoholic solutions of the volatile oils (except the imported orange-flower and rose waters and con- centrated chamomile water; see Water, Chamomile, Concentrated). Water, Bitter Almond. I. Oil of bitter almond m. 8 .. (or about drops 10) Distilled water fl.oz. 16 Dissolve the oil in the water by agi- tation and filter through a well-wetted filter.— U. S. P. II. Bitter almonds, coarse powder av.oz. 16 Water, alcohol, each sufficient Express the almonds so as to remove as much of the fixed oil as possible, powder the press cake, mix this with 25^2 fluidounces of water, and distil in such a way that steam will pass through PHARMACEUTICAL PREPARATIONS. m this mixture. Cool the condenser and receiver very carefully and collect 12 av.ounces of distillate in a receiver which contains 4 av.ounces (4^ fluid- ounces) of alcohol. The mixture of distillate and alcohol is to be assayed and then diluted with a mixture of 2 volumes of alcohol and 5 of water so that the product shall contain 1/10 per cent, of absolute hydrocyanic acid. — Germ. Pharm. Water, Bitter Almond, Diluted. Bitte r almond water fl.oz. 1 Distmed water fl.oz. 19 —Germ. (1st) and Austr. Pharms. Water, Bromin. This .nay be prepared according to the N. F. by mixing bromin with 30 times its weight of water, agitating occasionally during several hours, and then decanting the water from the un- dissolved bromin. Water, Camphor. I. Camphor gum gr. 60 Alcohol fl.dr. 1 Purified talc gr. 115 Distilled water, to make, .fl.oz. 16 Dissolve the camphor in the alcohol, triturate the solution with the talc, and after allowing the greater portion of the alcohol to evaporate spontaneously, con- tinue the trituration with the water gradually added; then pour the mixture upon a well-wetted filter, and pass the filtrate through the filter repeatedly un- til the water comes through clear. — N. F. II. Camphor gr. 7^ Alcohol sufficient Distilled water -. > fl.oz. 16 Dissolve the camphor in enough alcohol to make 25 minims of solution, add this in successive portions to the distilled water, shaking after each addition, fi- nally agitate occasionally until all the camphor is dissolved. — Brit. Pharm. Water, Caraway. (Aqua Carui.) Mix 654 av.ounces of caraway seed with 1 gallon of water and distil off Yz gallon. — Brit. Pharm. A qiucker process is to triturate 15 drops of oil of caraway with y 2 av.ounce of purified talcum until well mixed, then add 16 fluidounces of distilled water, macerate for 6 hours, and filter. Water, Carbolized. I. Glycerite of carbolic acid, U. S. P. 1890 ..fl.oz. iy 2 Water, to make fl.oz. 16 — U. S. P. 1870. If it is not desired to keep the glyc- erite on hand, the above may be pre- pared (approximately) from 2 fluidrams of carbolic acid in the fluid form, as it is usually kept on hand by pharmacists for dispensing purposes, 1 fluidounce of glycerin, and enough water to make 16 fluidounces. II. Carbolic acid, liquefied. . fl.dr. 3 or gr. 160 Distilled water, to make. . .fl.oz. 16 — Germ. Pharm. Water, Carminative. (Aqua Carmin- ativa. — Wind Wasser.) This may be prepared by- the follow- ing easy process : Oil of orange peel drops 7 Oil of caraway ." drops 7 Oil of lemon drops 7 Oil of fennel drops 7 Oil of coriander drops 7 Oil of spearmint drops 7 Alcohol fl.oz. 154 Chamomile water fl.oz. 14^ Mix the oils with the alcohol, add the water and filter. — H. Water, Castor, Bademacher's. (Aqua Catorei.) Canadian castor, cut finc.av.oz. 2.y 2 Alcohol fl.oz. 2 Water fl.oz. 28^ Mix, digest for 12 hours, then distil on a water bath so as to obtain 15 av.- ounces of distillate. — H. Water, Chamomile. Chamomile, German gr. 730 Water fl.oz. 48 Mix, macerate for 24 hours, and distil off 16 fluidounces.— Austr. Pharm. 528 STANDARD FORMULARY OF A quicker process is to triturate 3 drops of oil of chamomile with x / 2 av.- ounce of purified talcum until well mixed, then add 16 fluidounces of dis- tilled water, macerate for 6 hours, and filter. It may also be prepared by dilut- ing the concentrated chamomile water which is commercially available. Water, Chamomile, Concentrated. The preparation known by this name may be prepared as follows : Chamomile, German, bruised av.oz. 16 Alcohol fl-oz. 4 "Water sufficient Mix the chamomile with the alcohol, allow to stand for an hour in a closed vessel, place the mixture on the sieve of a distilling apparatus, and pass steam through the drug until 16 fluidounces of distillate have been obtained. — D. The chamomile water may be pre- pared from this by diluting it with g times its volume of distilled water. Water, Cherry. (Aqua Cerasorum Nigrorum.) The water known by this name may be prepared as follows (D.) : Bitter almond water fl.dr. 7 Distilled water, to make...fl.oz. 16 Water, Cherry-Laurel. (Aqua Lauro- Cerasi.) I. The genuine water is made by dis- tilling fresh cherry-laurel leaves with water. The tree grows in Europe and the water is imported into the United States. It is variable in character and hence the following formula by W. H. Pile for a factitious cherry-laurel water finds favor because yielding a uniform product : Diluted hydrocyanic acid....m. 320 Oil of bitter almond m. 16 (about drops 20) Alcohol fl.oz. 2 Distilled water, to make. . .fl.oz. 16 Dissolve the oil in the alcohol, add the acid and then the water. II. The formula of the Brit. Pharm. is as follows : Cherry-laurel leaves, fresh. fl.oz. i2 l A Water fl.oz. 40 Place the crushed drug with the water in a retort; distil 16 fluidounces of liq- uid; shake the product; filter if neces- sary; and adjust the product either by addition of hydrocyanic acid or of water so that the product shall contain 1/10 per cent, of hydrocyanic acid. Water, Chlorin. I. The U. S. Pharm. VIII discarded the old-time chlorin water made by dis- tillation of black oxid of manganese with hydrochloric acid and in its stead recognizes a "compound solution of chlorin," which is transferred now from the U. S. P. VIII to the N. F. Its for- mula is as follows: Potassium chlorate, granu- lated gr. 36 Hydrochloric acid m. 140 Distilled water, to make. . .fl.oz. 16 Add the acid, diluted with 2.y 2 flui- drams of distilled water, to the potas- sius chlorate contained in a flask of the :apacity of about 32 fluidounces. Insert in the flask a stopper perforated to ad- mit a funnel of the capacity of about 2 fluidounces containing about 75 grains of absorbent cotton well wetted with cold water; place the flask on a water bath containing boiling water, for a period of from 2 to 3 minutes; when the flask is completely filled with a greenish-yellow gas, remove it from the bath and add cold distilled water through the cotton in the funnel in two separate portions of 8 fluidounces each. After the addition of each separate por- tion of cold distilled water, stopper the flask securely, invert it, and thoroughly agitate the contents. The hydrochloric acid used in making this preparation should be of U. S. P. strength, 2> 2 P er cent, of absolute acid. If weaker, proportionately more of it must be used. This solution should be freshly made when wanted. Even when preserved from light and air, it deteriorates. This solution is described by the N. F. as an aqueous solution, containing, when freshly prepared, about 0.4 per PHARMACEUTICAL PREPARATIONS. 529 cent, of chlorin with some oxids of chlorin and potassium chlorid. Water, Chloroform. I. Chloroform, Distilled water, each sufficient Add enough chloroform to a con- venient quantity of distilled water, con- tained in a dark amber-colored bottle, to maintain a slight excess of the for- mer, after the contents have been re- peatedly and thoroughly agitated. — U. S. P. About 50 minims of chloroform will dissolve in 1 pint of water. When chloroform water is required for use, pour off the needed quantity of the solution, refill the bottle with dis- tilled water and saturate it by thorough agitation, taking care that there be al- ways an excess of chloroform present. This preparation, aside from its medi- cinal properties, is an efficient preserva- tive agent, and forms a good solvent, in place of water, for preparing solu- tions which are to be kept free from micro-organisms. II. Chloroform m. 20 Distilled water fl.oz. 16 Agitate together until the chloroform is dissolved. — Brit. Pharm. This contains one-half the chloroform present in the preparation of the Brit. Pharm. of 1885. Water, Cinnamon. (Cassia Water.) I. Oil of cassia cinnamon m. 15 Purified talc 7. .gr. 115 Distilled water, to make.. fl.oz. 10 Triturate the oil with the talc, add the distilled wtaer gradually under con- tinued trituration, filter, and pass the filtrate repeatedly through the filter un- til the water comes through clear. — U. S. P. II. The Brit. Pharm. preparation is made by mixing 6^4 av.ounces of bruised cin- namon bark with one gallon of water and distilling off one-half gallon. III. Cassia cinnamon, coarse pow- der av.oz. zVa Alcohol fl.oz. 2>Va Water, common, sufficient. Mix the drug with the alcohol and enough water, macerate for 12 hours, then distil off 32 fluidounces. The amount of water is not specified. The product is said to be turbid at first, later becoming clear. — Germ. Pharm. Water, Cresol. Saponated solution of cresol. av.oz. 1 Water av.oz. 9 — Germ. Pharm. For disinfecting purposes, common water may be used, but for medicinal or surgical purposes, distilled water only should be used. When ordinary water is used, a slightly turbid solution is ob- tained but with distilled water the solu- tion is perfectly clear. The product contains 5 p. c, of crude cresol. Water, Creosote. Creosote m. 80 Distilled water fl.oz. 16 Agitate the creosote vigorously with the water and filter through a well-wet- ted filter.. It should be freshly prepared when dispensed. — U. S. P. Water, Dill. (Aqua Anethi.) Dill fruit (seed) av.oz. 6^4 Water gal. 1 Mix and distil off one-half gallon. —Brit. Pharm. This may be more conveniently pre- pared by triturating 15 drops of oil of dill with T /i av.ounce of purified talcum until well mixed, adding 16 fluidounces of distilled water, macerating for 6 hours, and filtering. Water, Distilled. See under heading Water. Water, Distilled, Sterilized. Water, freshly distilled, boiled for 30 minutes in a sterilized flask, the mouth of which is protected with a pledget of sterilized, purified cotton. 530 STANDARD FORMULARY OF Instead of the fresh elder flowers, an equivalent quantity of elder flowers, preserved, while fresh, with common salt, may be used. The salt-preserved flowers are commercially available. Water, Fennel. (Aqua Fceniculi.) I. Oil of fennel m. 15 Purified talc gr. 115 Distilled water, to make. . .fl.oz. 16 Triturate the oil with the talc, add the distilled water gradually with continued trituration, filter, and pass the filtrate through the filter repeatedly until the water comes through clear. — U. S. P. The preparation of the Brit. Pharm. is made by mixing 6^ av.ounces "of fennel with one gallon of water and distilling half a gallon. II. Fennel, bruised av.oz. 2, gr. 60 Water sufficient Mix and distil 64 av.ounces of liquid. — Germ. Pharm. Water, Lime. (Solution of Lime — Solution of Calcium Hydroxid — Liquor Calcis — Aqua Calcis or Calcariee.) I. This is a saturated aqueous solution of calcium hydrate prepared by slaking 90 grains of lime by the very gradual addition of 6^2 fluidounces of distilled water, and agitate occasionally during one-half hour. Allow the mixture to settle, decant the liquid, throw the lat- ter away, to the residue add 58 fluid- ounces of distilled water, agitate thor- oughly, let the mixture stand for 24 hours, agitate again, then let the coarser particles of solid matter subside, and pour the liquid, holding the undissolved lime in suspension, into a glass-stop- pered bottle. From time to time shake the bottle so as to keep the solution sat- urated. Pour off the clear liquid when it is wanted for use. The lime for this purpose should not be common building lime, but should be prepared from marble or chalk. Lime or calcium oxid made from marble may be purchased in the market. The product should contain not less than 0.14 per cent, of pure calcium hydroxid. The percentage of the latter present varies with the temperature at which the solution is prepared, being about 0.17 per cent, at 15 deg. C, the percentage diminishing as the tempera- ture rises. II. Calcium hydroxid (slaked hme) gr. 365 Distilled water sufficient Wash the lime with distilled water until free from chlorids, then agitate it in a green glass bottle with one-half gallon of distilled water for 2 or 3 min- utes, and set aside for 12 hours. — Brit. Pharm. The clear solution may be drawn off with a siphon as it is required for use, and should be transferred to a green glass bottle. Slaked lime may be prepared by slak- ing quicklime with one-third its weight of water. III. Quicklime av.oz. 1 Distilled water sufficient Slake the lime with 4 fluidounces of the water, then add 48 fluidounces more of water, mix well, let stand for several hours, then decant the supernatant liq- uid, to the residue add 48 fluidounces more of water, transfer to a bottle, and keep in a cool place.— Germ, and Austr. Pharms. IV. For the corresponding homeo- pathic preparation, see Solution of Cal- cium Hydrate. Water, Linden. (Aqua Tilice.) Linden flowers, dry av.oz. V/ 2 Or fresh flowers av.oz. 7 l / 2 Water fl.oz. 32 Mix and distil 16 fluidounces. — D. modified. Linden flowers are derived from our common basswood tree. PHARMACEUTICAL PREPARATIONS. 531 "Water, Nux Vomica, Rademacher's. (Aqua Nucum Vomicarum — Aqua Strychni Seminis — Aqua Strych- ni.) Nux vomica, cut into small pieces av.oz. io^4 Alcohol fl.oz. i l / 2 Water sufficient Mix, macerate for 24 hours and distil 16 av.ounces. — H. Water, Orange-Flower. (Aqua Naphse — Aqua Aurantii Florum.) Stronger orange-flower water, Distilled water, each, equal volumes The stronger water to be used for this purpose is the imported so-called triple orange-flower water. — U. S. P. These waters should be kept in loose- ly stoppered bottles in a dark place, pref- erably also in a cool location. According to the Brit. Pharm., the stronger water is to be diluted with twice its volume of distilled water. "Water, Ozonized. A solution of 15 to 30 grains of potas- sium permanganate in 16 fluidounces of distilled water has been known by this name. Water, Pennyroyal. (Aqua Hedeo- mae.) Oil of pennyroyal m. 15 Magnesium carbonate gr. 30 Distilled water fl.oz. 16 Triturate the oil with the carbonate, then add the water, and filter. — Eclectic. Water, Peppermint. I. Oil of peppermint m. 15 Purified talc gr. 115 Distilled water, to make, .fl.oz. 16 Triturate the oil with the talc, add the water gradually with continued tritura- tion, filter, and pass the filtrate through the filter repeatedly until the water comes through clear. — U. S. P. II. Oil of peppermint m. 30 Water , fl.oz. 96 Mix and distil 64 fluidounces. — Brit. Pharm. III. Peppermint herb, cut coarse. av.oz. 6 l /> Water sufficient 34 Mix and distil 64 av.ounces. — Germ. Pharm. Water, Phosphoric. This preparation, used by homeopaths and eclectics, is water in which phos- phorus has been macerated, as for ex- ample the water in which stick phos- phorus has been preserved. Water, Pimento. Pimento, bruised av.oz. 1 Water fl.oz. 38 Mix and distil off 19 fluidounces. — Brit. Pharm. It may also be prepared by triturating 15 drops of oil of pimento with l / 2 av. ounce of purified talcum until well mixed, adding 16 fluidounces of water, macerating for 6 hours and filtering. Water, Quassia, Rademacher's. Quassia bark, cut av.oz. iy 2 Quassia wood, rasped av.oz. 6 Alcohol fl.dr. 19 Water, sufficient. Mix, macerate for 24 hours, and dis- til 16 av. ounces of liquid. — H. Water, Rose. I. Stronger rose water. Distilled water, equal volumes of each. Mix immediately before use. — U. S. P. In the Brit. Pharm. the stronger rose water is directed to be diluted with dou- ble its volume of distilled water. The stronger rose water to be used for this preparation is the imported triple rose water obtained as a by-prod- uct in the distillation of oil of rose. Stronger rose water should be kept in well-stoppered bottles in a dark place. Of course, rose water may be pre- pared from oil of rose, but the product is not so good, does not have the pleas- ant, fragrant odor of the water prepared from a good imported triple water. If it is prepared from oil of rose, about 15 or 20 drops of the latter may be mixed in a bottle with one-half gallon of warm distilled water, the mixture allowed tc stand until cold, and then filtered. 532 STANDARD FORMULARY OF II Oil of rose drops 7 Distilled water, lukewarm, .fl.oz. 60 Mix, agitate, and filter. — Germ. Pharm. Water, Sedative. (Lotio Ammonia- ealis Camphorata — Eau Sedative de Raspail — Aqua Sedativa.) Ammonia water, 10 p.c. .. .fl.oz. 2 Spirit of camphor fl.dr. 1^2 Sodium chlorid gr. 480 Water to make fl.oz. 16 Dissolve the sodium chlorid in about 8 fluidounces of water, add the ammonia water and spirit of camphor, and finally enough water to make 16 fluidounces of product. — N. F. Shake the liquid when it is to be dis- pensed The above is practically the formula of the Codex. Raspail himself used three strengths of sedative water, which differed from each other on the proportion of ammo- nia water they contained. They were prepared with strong ammonia water and contained the equivalents respective- ly of 2, 2^4 and 2>Va fluidounces of 10 p. c. ammonia water. Water, Spearmint. Oil of spearmint m. 15 Purified talc gr. 115 Distilled water, to make.. . .fl.oz. 16 Triturate the oil with the talc, add the water gradually with continued tritura- tion, filter, and pass the filtrate repeat- edly through the filter until the water comes through clear. — U. S. P. The preparation of the Brit. Pharm. is made by mixing 30 minims of oil with 96 fluidounces of water and distilling 64 fluidounces. "Water, Tar. See Infusion of Tar. Water, Thymol. The following may be dispensed for this: Thymol gr. 1 Distilled water fl.oz. 4 Warm the water to about 60 deg. C. and agitate the thymol with it until it is dissolved. Water, Tobacco, Rademacher's. (Aqua Nicotianse.) Tobacco leaves, freshly gath- ered av.oz. 16 Alcohol fl.oz. 3 J / 2 Water, sufficient. Cut the leaves, add the alcohol and water and then distil 16 av. ounces. — H. Water, Tolu. This may be prepared as follows : Tincture of tolu fl.dr. 1 Magnesium carbonate gr. 60 Water fl.oz. 16 Triturate the tincture with the magne- sium carbonate until well mixed, add the water gradually with stirring, and filter. Tolu water may also be prepared by boiling tolu balsam with water. This is used to some extent in lieu of distilled water for making mucilage of acacia. Wax, Yellow, Filtered. Yellow wax av. oz. 16 Sodium sulfate, dried, fine pow- der av. oz. 24 Melt the wax at the lowest possible temperature, add the sodium sulfate, maintain the wax at the same tempera- ture for 15 minutes, stirring frequently, and filter by hot filtration. This is an excellent -product suitable for ointments and cerates provided the temperature employed in preparation was not too high. — D. Wines (Vina) . All wines, including all medicated wines, were dropped from the U. S. P. Some of them have been transferred to the N. F., but the "red" and "white" wines have been dropped altogether, di- luted alcohol being used instead. One reason for the deletion of the wines as a menstruum was that they were of such variable alcoholic strengths, and another reason, perhaps the principal one, was that they had to go, along with the other alcoholic "beverages." PHARMACEUTICAL PREPARATIONS. 583 Wine of Aloes. Purified aloes gr. 420 Cardamon gr. 70 Ginger gr. 70 Stronger white wine to make av.oz. 16 Mix the aloes, cardamom and ginger, and reduce them to a moderately coarse (No. 40) powder. Macerate the powder with 14J/2 fluidounces of stronger white wine for seven days, with occasional agi- tation, anl filter through paper, adding, through the filter, enough stronger white wine to make the filter liquid weigh 16 av. ounces. Wine of Antimony. (Antimonial Wine — Vinum Stibiatum.) I. Tartar emetic gr. 30 Distilled water fl.oz. 1 Alcohol ., fl.oz. 2^4 Sherry wine, to make fl.oz. 16 Heat the water to boiling, dissolve the tartar emetic in it, add this solution to the alcohol previously mixed with 11^/2 fluidounces of wine, allow the mixture to cool, filter it, and add enough wine through the filter to make 16 fluidounces of product. — N. F. The tartar emetic should be pure, not the ordinary commercial powder. II. In the Brit. Pharm., slightly more tar- tar emetic is used than in the U. S. P., viz., 33 grains instead of 30. III. Tartar emetic gm. 30 Sherry wine, to make fl.oz. 16 Mix, dissolve and filter. — Germ. Pharm. Wine, Aromatic. Lavender flowers gr. 70 Origanum herb gr. 70 Peppermint herb gr. 70 Rosemary leaves gr. 70 Sage gr. 70 Wormwood gr. 70 Stronger white wine, to make av.oz. 16 Mix the drugs, reduce them to coarse powder, moisten with 5 fluidrams of the wine, pack in a percolator, and perco- late with the stronger white wine to make 16 av.ounces of percolate. — U S. P. 1880. This is the aromatic wine of the Co- dex. Wine of Beef. (Beef and Wine— Vinum Carnis.) Extract of beef. . . . gr. 480 Water, hot fl.oz. 2 Simple syrup fl.oz. 4 Compound spirit of orange.. m. 15 Alcohol fl.oz. 4 Sherry wine, to make fl.oz. 32 Triturate the extract with hot water, and add with continuous stirring the alcohol. Allow the mixture to stand for 3 days or more, then filter, distil off the alcohol, add the spirit and syrup to the residue and enough wine to make 32 fluidounces, and filter if necessary. The extract of beef for this prepara- tion" is that which is prepared by Liebeg's method.— N. F. Wine of Beef and Iron. (Beef, Wine and Iron.) 1. Extract of beef gr. 480 Tincture of iron citrochlo- rid fl.oz. 1 Compound spirit of orange.. m. 15 Water, hot fl.oz. 2 Alcohol fl.oz. 4 Simple syrup fl.oz. 4 Sherry wine, to make. ... .fl.oz. 32 Triturate the extract with the hot wa- ter and add, with continuous stirring, the alcohol. Allow the mixture to stand 3 days or more; then filter, distil off the alcohol, add the spirit, tincture and syrup to the residue and enough wine to make 32 fluidounces. Filter if necessary. Each fluidram represents 2 gr. of ex- tract of beef and 2 minims of tincture of iron citrochlorid. The extract of beef used should be that prepared by Liebig's process. — N. F. Other flavoring agents may be used besides the compound spirit of orange, such as tincture of sweet orange peel or another wine may be used such as An- gelica or Muscatelle. In spite of its apparent simplicity, this is a troublesome preparation to keep, as '534 STANDARD FORMULARY OF it invariably deposits a precipitate. To avoid this various expedients have been resorted to such as detannation of the wine, the use of fresh beef or beef pep- tone for the extract of beef, the use of other iron compounds, etc. The follow- ing formulas present examples of differ- ently prepared products. II. Extract of beef gr. 512 Iron phosphate, scale gr. 128 Water, hot fl.oz. 2 Simple syrup fl.oz. 4 Tincture of sweet orange- peel .fl.oz. 2 Sherry or other suitable wine, to make .fl.oz. 32 Ferric hydrate, sufficient. Detannate the mixed tincture and 12 fluidounces of the wine by agi- tation, with about 4 av.ounces of freshly prepared (moist) ferric hy- drate (see Iron Hydrate for method of preparation), allowing to stand for 24 hours, filtering, and passing enough wa- ter through the filter to restore the origi- nal volume of liquid. Test a small amount of this liquid by adding some tincture or solution of ferric chlorid; if discoloration occurs, the liquid must be treated with more ferric hydrate in the same manner as before. To the filtrate, add the extract and iron salt previously dissolved in the water, and finally add the syrup. Instead of the iron phosphate and a portion of the water, S J / 2 .fluidrams of tincture of iron citrochlorid may be used. III. Extract of beef gr. 700 Iron phosphate, scale gr. 256 Pimento, powder gr. 20 Clove, powder gr. 6 Tincture of sweet orange- peel fl.oz. 3 Simple syrup fl.oz. 3 Stronger white wine fl.oz. 22 Water, to make fl.oz. 32 Dissolve the extract in 2 fluidounces of warm water, the iron salt in l / 2 fluid- ounce of warm water, mix, add the other ingredients, macerate for 4 days, agitat- ing occasionally, and filter. — D. C. Form. IV. Extract of beef av.oz. 2 Iron citrate, soluble gr. 480 Water, warm fl.oz. 2 Simple elixir fl.oz. 8 Angelica wine, to make. . . .fl.oz. 32 Dissolve the extract and iron salt in the warm water, add the elixir and wine, and filter. V. Beef peptone gr. 128 Tincture of iron citro- chlorid fl.oz. 1 Water, warm fl.oz 2 Simple syrup fl.oz. 2 Simple elixir fl.oz. 2 Sherry or other suitable wine fl.oz. 25 Dissolve the peptone in the warm wa- ter, add the other ingredients, and filter. The beef peptone is now commercially available. VI. Fresh beef, lean, chopped fine, or cut in a food chopper.av.oz. 20 Iron citrate, scale gr. 270 Compound tincture of car- damom fl.oz. 1 l / 2 Tincture of sweet orange- peel fl.oz. i l / 2 Alcohol fl.oz. 3 Simple syrup fl.oz. 6 Sherrv wine fl.oz. 36 Milk fl.oz. 1 Water, to make fl.oz. 64 Macerate the beef with 16 fluidounces of cold water for several hours, then reduce the temperature to 40 deg. C. and strain with expression. Add the milk to the wine, mix well, set aside a few hours, then filter. To the filtrate add the beef liquid, the iron salt dissolved in 1 fluid- ounce, the tinctures, alcohol and syrup, and, if necessary to make 64 fluidounces of product, wash the beef residue with sufficient warm water to make this vol- ume. Let the mixture stand a few days, and filter. Wine of Beef, Iron and Cinchona. (Beef, Wine, Iron and Cinchona.) Quinine sulfate gr. 30 Cinchonidine sulfate gr. 15 Citric acid gr. 11 Wine of beef and iron fl.oz. 32 Reduce the alkaloid sulfates and the acid to fine powder by trituration and PHARMACEUTICAL PREPARATIONS. 535 dissolve them in the wine. Filter if necessary. Each fluidram represents 2 gr. of beef extract, 2 m. of tincture of iron citrochlorid, and small quantities of cin- chona alkaloids. Wine of Beef, Iron and Coca. (Beef, Iron, Wine and Coca.) Extract of beef. . . gr. 256 Tincture of iron citrochlo- rid fl.dr. 4% Water, hot fl.oz. 1 Simple syrup fl.oz. 1 Fluid extract of coca fl.dr. 10^2 Sherry wine, to make fl.oz. 16 Triturate the extract of beef with the water until dissolved, add 10 fluidounces of wine, then the tincture, syrup, fluid extract, and the remainder of the wine, and filter. Each fluidram represents 2 gr. of beef extract, 2 m. of tincture of iron, and 5 gr. of coca. Wine, Camphorated. Camphor gr. 145 Alcohol fl.dr. 3 Mucilage of acacia fl.oz. 1 Sherry wine fl.oz. 14^ Dissolve the camphor in the alcohol, and gradually add the mucilage and wine previously mixed, agitating constantly. — Germ. Pharm. Wine of Cascara Sagrada. Bitterless fluid extract of cas- cara sagrada fl.oz. I Gelatin gr. 10 Distilled water fl.dr. 2 Sugar av.oz. 1 Sherry wine fl.oz. 18 Dissolve the gelatin in the water by the aid of a gentle heat, add the wine, then the fluid extract and sugar, shake well, set aside in a cool place for 8 days, and filter.— D. The gelatin prevents subsequent tur- bidity of the preparation. Wine of Cinchona. I. Red cinchona, coarse pow- der av.oz. 194 Gelatin gr. 7 Sugar av.oz. i l / 2 Tincture of bitter orange peel.m. 15 Water, warm m. 70 Sherry wine fl.oz. 15^ Dissolve the gelatin in the water, add the sherry wine and the cinchona, ma- cerate for 8 days at a temperature of 60 to 70 deg. C, agitating occasionally, ex- press, add the sugar and tincture, agi- tate till the sugar is dissolved, set aside in a cool place for 14 days, and filter. — Germ. Pharm. II. The preparation may be made from the fluid extract as follows: Fluid extract of red cin- chona fl.dr. s l A Glycerin fl.oz. 2% Stronger white wine, to make fl.oz. 16 Mix, let stand a few days, and filter. III. Wine of cinchona prepared according to the preceding formulas precipitates copiously ; the following formula is high- ly recommended as producing a satis- factory product: Cinchona, red, coarsepowder.gr. 320 Hydrochloric acid m. 20 Citric acid gr. 10 Water fl.oz. 2 Sherry wine fl.oz. 7 Malaga wine fl.oz. 7 Simple syrup fl.oz. 1^2 Brandy fl.dr. 6 Tincture sweet orange peel. . .m. 40 Alcohol fl.oz. I Heat the cinchona with the hydro- chloric acid and water in a closed vessel on a water bath for 24 hours, then pack the mass in a percolator, add the alcohol, macerate for 6 days, then percolate slow- ly with the sherry wine containing the citric acid in solution, and finally per- colate with the Malaga wine, syrup, tinc- ture, and brandy mixed. The product has a pleasant, aromatic, only slightly bitter taste. Wine of Cinchona, Aromatic. This is a practical modification of the Eclectic formula: Red cinchona av.oz. 1 Coriander gr. 15 Cinnamon gr. 30 Sugar av.oz. 2 Tartaric acid gr. 15 Stronger white wine sufficient. Reduce the drugs to moderately coarse 536 STANDARD FORMULARY OF powder, and extract by the usual process of percolation, using the wine as a men- struum. Collect 16 fluidounces of per- colate and in this dissolve the sugar and acid. The stronger white wine may be made from Madeira or Catawba wine if de- sired. This is a pleasant, aromatic tonic. Wine of Cinchona and Cacao. Fluid extract of yellow cin- chona fl.oz. I Tincture of cacao fl.oz. I Simple syrup fl.oz. 2 Angelica wine fl.oz. 12 Mix and filter, if necessary. Wine of Cinchona and Coca. Fluid extract of coca fl.oz. I Wine of cinchona and cacao.fl.oz. 15 Wine of Coca. Fluid extract of coca fl.oz. 1 Alcohol fl.oz. i J A Sugar av.oz. 1 Port wine, to make fl.oz. 16 Dissolve the sugar in 8 fluidounces of the wine, add the fluid extract and alco- hol and the remainder of the wine, set tr:e mixture aside for 2 days, then filter through paper in a well-covered funnel. Wine of Coca, Aromatic. Fluid extract of coca fl.oz. I Compound elixir of taraxacum. m. 75 Syrup of coffee fl.dr. 3 Port wine fl.oz. 2^ Aromatic elixir fl.oz. 4]/ 2 Sherry wine, to make fl.oz. 16 Mix the five first-named ingredients with 714 fluidounces of sherry wine. Let the mixture stand several days, if con- venient, then filter. Each fluidounce represents about 30 gr. of coca. Wine of Coca With Beef. A preparation of this kind may be rr.ade as follows: Extract of beef gr. 256 Wine of coca fl.oz. 16 Triturate together, let stand a few days, and filter. Wine of Cod-Liver Oil. A preparation of this kind may be made as follows: Gaduol gr. 64 Alcohol fl.dr. 4 Simple syrup fl.oz. 2 Fuller's earth av.oz. y 2 Port wine, to make fl.oz. 16 Mix the gaduol with the alcohol, and add the fuller's earth, rub well together, and then add the syrup and 13 fluid- ounces of wine, let stand a day or two, shaking occasionally, then filter, passing the remainder of the wine through the filter. A preparation of the same character, but of a more distinctive taste and ap- pearance, may be compounded as fol- lows: Gaduol gr. 64 Alcohol fl.dr. 4 Fuller's earth av.oz. y 2 Port wine, claret wine, equal parts of each, to make fl.oz. 16 Proceed as before. These preparations will be improved by adding a small amount of spirit of orange. Compounds prepared as above contain 25 per cent, of the active medicinal prin- ciples of col-liver oil. Wine of Colchicum. The preparation of the Brit. Pharm. of this name is wine of colchicum root. See Wine of Colchicum Root, No. III. The preparation of the Germ. Pharm. of this name is wine of colchicum seed. See Wine of Colchicum Seed No. III. Wine of Colchicum Root. I. Colchicum root, No. 30 pow- der av.oz. 6^4 Alcohol fl.oz. 2Y2 Sherry wine, to make fl.oz. 16 Mix the alcohol with 13 fluidounces of wine, moisten the drug with i l / 2 fluid- ounces of menstruum, pack it moder- ately in a conical glass percolator, and gradually pour upon it, first, the remain- der of the menstruum, and afterwards enough wine to make 16 fluidounces of percolate.— N. F. PHARMACEUTICAL PREPARATIONS. 537 The N. F. remarks that this formula is given for reference only. If wine of colchicum is prescribed, the much weak- er wine of colchicum seed should be dis- pensed. II. Colchicum root, No. 20 pow- der av.oz. z l A Sherry wine fl.oz. 16 Mix, macerate for 7 days, agitating occasionally, strain with expression, and filter.— Brit. Pharm. Wine of Colchicum Seed. I. Fluid extract of colchicum seed fl.dr. 13 Alcohol fl.oz. 2,y 2 Sherry wine, to make fl.oz. 16 Mix, set aside for 2 days, then filter through paper, in a well-covered funnel. — N. F. n. The Eclectic preparation is made by extracting 2 x / 2 av.ounces of drug with enough sherry wine to make 15 fluid- ounces. III. Colchicum seed, No. 20 pow- der gr. 730 Sherry wine fl.oz. 16 Mix, macerate for 8 days, agitating occasionally, strain with expression, set aside for several days, and filter. — Germ. Pharm. Wine of Comfrey, Compound. (Re- storative Wine Bitters — Vinum Symphyti Compositum.) Comfrey av.oz. % Solomon's seed av.oz. 34 Helonias av.oz. ^ Roman chamomile gr. 55 Columbo gr. 55 Gentian gr. 55 Cardamom seed gr. 55 Sassafras gr. 55 Sherry wine, to make fl.oz. 16 Reduce the drugs to moderately coarse powder, and extract by percolation with the wine so as to obtain 16 fluidounces of percolate. — Eclectic modified. This is a tonic for diseases peculiar to females. Wine of Condurango. Condurango, No. 20 powder.gr. 730 Sherry wine fl.oz. 16 Mix, macerate for 8 days, agitating oc- casionally, strain with expression, set aside for several days, and filter. — Germ. Pharm. Wine, Diuretic, Trousseau's. Squill gr. 48 Digitalis gr. 96 Juniper berries gr. 480 Potassium acetate gr. 144 Sherry wine fl.oz. 16 Mix, macerate for 7 days, agitating occasionally, express and filter. — H. Wine of Elder. (Hydragogue Tinc- ture — Vinum Sambuci.) Elder bark av.oz. 1 Parsley root av. oz. 1 Sherry wine, to make. fl.oz. 16 Extract the mixed and powdered drugs by percolation or maceration. — Eclectic. Wine of Ergot. Fluid extract of ergot fl.oz. z l A Alcohol fl.dr. 6^ Sherry wine, to make fl.oz. 16 Mix, set aside for 2 days, then filter through paper, in a well-covered funnel. Wine of Golden Seal, Compound.. (Wine Bitters.) Golden seal gr. 20 Tulip tree bark gr. 20 Bitter root (dogsbane) gr. 20 Prickly-ash berries gr. 10 Sassafras bark gr. 10 Capsicum gr. 10 Sherry wine, to make fl.oz. 16 Extract the mixed drugs in coarse powder by percolation or maceration. — Eclectic. Wine of Hellebore, Compound. Black hellebore gr. 580 Logwood gr. 580 Helonias root gr. 580 Sherry wine, to make fl.oz. 16 Reduce the drugs to moderately coarse powder and extract by percolation or maceration with the wine so as to obtain 16 fluidounces of product. — Eclectic. This is a tonic and cathartic, with a direct influence on the female organs. 538 STANDARD FORMULARY OF The dose is I or 2 tablespoonfuls every 3 or 4 hours. Wine of Hypophosphites, Compound. Calcium hypophosphite gr. 128 Potassium hypophosphite gr. 64 Sodium hypophosphite gr. 64 Ferric hypophosphite gr. 8 Manganese hypophosphite. . .gr. 8 Quinine hydrochlorid gr. 4 Potassium citrate gr. 20 Citric acid gr. 8 Strychnine (alkaloid) gr. 1% Fluid extract of coca fl.dr. io>4 Alcohol fl.dr. 1% Glycerin fl.dr. 5 Sugar av.oz. 6 Distilled water... ^ fl.oz. 4 Stronger white wine, to make fl.oz. 16 Mix the fluid extract with the glycerin and add 6 l / 2 fluidounces of stronger white wine. Allow to stand 24 hours and fil- ter. Triturate the hypophosphites of iron and manganese with the potassium ci- trate, citric acid and 4 fluidounces of water and gently warm the mixture for a few minutes until all is dissolved. Dissolve the other hypophosphites and the quinine salt in 3^2 fluidounces of wa- ter, to which add the strychnine pre- viously dissolved in the alcohol. Add the second solution to the third and filter; dissolve the sugar in this filtrate by percolation, passing enough water through the percolator to make the percolate measure 8 fluidounces. To this add the fluid extract mixture and enough stronger white wine to make 16 fluidounces. Each fluidram represents I gr. of cal- cium hypophosphite, r / 2 gr. each of po- tassium and sodium hopophosphites, 1/16 gr. each, of iron and manganese hypo- phosphites, 1/32 gr. of quinine hydro- chlorid, 1/100 gr. of strychnine and 5 gr. of coca. — Cine. Acad. Pharm. Wine of Ipecac. I. Fluid extract of ipecac fl.oz. i z / 2 Alcohol t< fl.oz. iy 2 Sherry wine fl.oz. 12 Mix, set aside for 2 days, then filter through paper in a well-covered funnel. — N. F. II. Fluid extract of ipecac of the Brit. Pharm fl.dr. 6^ Sherry wine, to make fl.oz. 16 —Brit. Pharm. III. Ipecac, No. 20 powder gr. 730 Sherry wine fl.oz. 16 Mix, macerate for 8 days, agitating occasionally, strain with expression, and filter. — Germ. Pharm. Wine of Iron. (Vinum, Ferri — Cha- lybeate or Steel Wine.) I. Iron and ammonium citrate (so- called "soluble citrate of iron") gr. 290 Tincture of sweet orange- peel fl.oz. 1 Simple syrup fl.oz. 13 Sherry wine, to make fl.oz. 16 Dissolve the iron compound in 11 fluidounces of wine, add the tincture and syrup and enough wine to make 16 fluidounces. Set the mixture aside for 2 days, then filter through paper in a well- covered funnel. — N. F. This preparation was known as "wine of iron citrate" in the U. S. P. 1890. See also Wine of Iron Citrate. II. Iron, in wire gr. 365 Sherry wine fl.oz. 16 Set aside for 30 days in a closed ves- sel, the iron wire being almost, but not quite, immersed in the sherry, the vessel being frequently agitated, and the stop- per occasionally removed, then filter. — Brit. Pharm. III. The acid potassium tartrate present in the wine in No. II. reacts upon the iron to form iron and potassium tartrate. A wine containing a definite amount of this salt may be prepared as follows: Iron and potassium tartrate.. gr. 160 Water, warm fl.oz. 4 Ammonia water sufficient Angelica wine, to make fl.oz. 16 Dissolve the salt in the water, care- fully neutralize the acid in the wine with ammonia, mix the two liquids, and filter. PHARMACEUTICAL PREPARATIONS. 539 Wine of Iron, Bitter. (Wine of Iron and Quinine Citrate.) I. Soluble iron and quinine cit- rate gr. 365 Tinct. of sweet orange peel.fl.oz. 1 Simple syrup fl.oz. 5 Sherry wine, to make fl.oz. 16 Dissolve the iron and quinine citrate in 8 fluidounces of wine, add the tinc- ture and syrup and the remainder of the wine, set the mixture aside for 2 days, then filter through paper, in a well-cov- ered funnel.— N. F. II. Mitchell's formula: Cinchona, yellow, coarse powder gr. 192 Gentian, coarse powder gr. 128 Soluble iron citrate gr. 192 Brandy fl.oz. 1 Alcohol fl.oz. 1 Oil of orange m. 15 Sugar av.oz. 2 Sherry wine fl.oz. 13 Solution of iron tersulf ate. fl.oz. 2 Distilled water, ammonia water, each sufficient Dissolve the oil in the alcohol, mix this with the wine and brandy, perco- late the ground drugs with this liquid, adding through the drug enough water to make the percolate measure 15 fluid- ounces. Detannate this liquid by means of ferric hydrate prepared by diluting the iron solution with 4 fluidounces of water, adding ammonia water in slight excess, collecting the precipitate, and washing and draining it thoroughly. Mix this precipitate with the percolate, and agitate occasionally until a filtered por- tion has a light yellow color and does not discolor with tincture or solution of iron chlorid. Filter the total liquid, to the filtrate add the iron citrate dissolved in a small amount of warm water, and then through the filter add enough wa- ter to make a total liquid of 16 fluid- ounces. Wine of Iron Citrate. The preparation of the U. S. P. 1890 of this name is now known as wine of iron, N. F. ; the preparation of the Brit. Pharm. of this name is as fol- lows : Iron citrate, soluble (ammo- nio-citrate) gr. 135 ' Orange wine of the Brit. Pharm., to make fl.oz. 16 Dissolve the iron salt in the wine, agi- tate occasionally for 3 days, and filter. Wine of Iron and Potassium Tartrate. See Wine of Iron. Wine of Iron, Sweet. This is a good formula: Iron citrate, soluble gr. 128 Distilled water, warm fl.dr. 4 Tinct. of sweet orange peel.fl.oz. 1 Simple elixir fl.oz. 1 Simple syrup fl.oz. 3 Sherry wine, to make fl.oz. 16 Dissolve the iron citrate in the water and add the other ingredients. Wine, Kola. I. The following formula may be used: Kola, No. 20 powder av.oz. J4 Sherry wine fl.oz. 16 Mix, macerate for 7 days, and filter. Such a preparation has a disagreeable taste; the following is an improvement, as it has a clear bitter taste : II. Roasted kola, No. 20 pow- der av.oz. Yi Sherry wine fl.oz. 16 Mix, macerate for 7 days, agitating occasionally, and filter. This may be sweetened by the addi- tion of some simple syrup or sugar. III. Formula of Munich Apothecaries' Society : Fluid extract of kola fl.dr. 6 l / 2 Sherry wine, to make fl.oz. 16 Wine of Licorice with Opium. (Vin- um Liquiritiae Thebaicum — Ros- en's Broest Droppar. Opium, powder gr. 145 Spanish saffron, coarse pow- der .... gr. 145 Extract of licorice, powder, .gr. 145 Malaga wine : . fl.oz. 16 Macerate the drugs for 5 days with the wine, and filter. — Swed. Pharm. The product contains 2 per cent, of each of the drugs. 540 STANDARD FORMULARY OF Wine of Opium. Opium, granulated gr. 730 Saigon cinnamon, No. 60 powder g r - 7 2 Clove, No. 30 powder gr. 72 Alcohol, sherry wine, each, to make fl.oz. 16 Mix the alcohol and wine in the pro- portion of 3 volumes of the former^ to 17 of the latter. Macerate the drugs in a stoppered container, in a moderately warm place, with 12 fluidounces of this menstruum, during 7 days, agitating oc- casionally; then filter through absorbent cotton, in a well-covered funnel, return- ing the first portions until the filtrate passes perfectly clear, and finally pass enough menstruum through the residue to make the liquid measure 16 fluid- ounces. The granulated opium should be of the strength specified by the U. S. P., that is it should contain 10 to 10^4 per cent, of crystallized opium. Wine of Orange. (Orange Wine — Vinum Aurantii.) Oil of bitter orange peel m. 8 (about drops 12) Alcohol m. 75 Purified talcum gr. 120 Sherry wine, to make fl.oz. 16 Triturate the talcum, first with the alcohol, in which the oil has previously been dissolved, and afterwards with 12 fluidounces of wine, gradually added. Filter the mixture through a wetted fil- ter, returning the first portions of the filtrate until it runs through clear, and lastly, pass enough wine through the filter to make 16 fluidounces. This preparation of N. F. Ill was used only as a pleasant vehicle. In the Brit. Pharm., it is described as a wine made by the fermentation of a saccharine solution to which fresh bit- ter-orange peel has been added. Wine of Orange, Compound. (Elixir Aurantiorum Compositum — Com- pound Elixir of Orange — Vinum Aurantii Compositum.) Bitter orange peel av.oz. 2>Va Wormwood gr. 480 Buckbean gr. 480 Cascarilla gr. 480 Cinnamon, cassia gr. 320 Gentian gr. 320 Potassium carbonate gr. 75 Sherry wine, to make fl.oz. 16 Reduce the first six drugs to a mod- erately coarse (No. 40) powder, mix with the potassium carbonate, moisten the mixture with sherry wine, and mac- erate during 24 hours. Then pack it in a percolator, and percolate with sherry wine, in the usual manner, until 16 fluid- ounces of product are obtained. This wine was formerly official in the Germ. Pharm., which directed to mac- erate the orange peel, cinnamon and po- tassium carbonate, with the sherry wine, and then to add the other drugs in form of extracts. The proportions above giv- en produce a product practically identi- cal with this. See Elixir of Orange, Compound. — N. F. Wine, Orange, Detannated. Orange wine, Brit. Pharm. . .gall. 1 Gelatin, cut small gr. 90 Macerate for 14 days, and decant. — Brit Form. Wine of Pancreatin. Such preparation may be made as fol- lows : Pancreatin, pure gr. 160 Simple elixir fl.oz. 5 Sherry wine fl.oz. 1 1 Mix all, macerate for 24 hours, and filter. Wine of Pepsin. (Pepsin Wine.) I. Glycerite of pepsin fl.oz. 3 Alcohol fl.oz. i]/ 2 Sherry wine fl.oz. 10^2 Mix the alcohol and wine, add the glycerite, and mix thoroughly. — N. F. Each fluidram represents 1 gr. of U. S. P. pepsin. This preparation should be prepared fresh when needed. II. Pepsin (1:100) gr. 180 Glycerin fl.dr. 2 Hydrochloric acid m. 15 Water fl.dr. 3 Simple syrup fl.oz. 1 l /i Tinct. of bitter orange peeL.m. 15 Sherry wine, to make fl.oz. 16 —Germ. Pharm. PHARMACEUTICAL PREPARATIONS. 541 III. Pepsin gr. 256 Hydrochloric acid m. 96 Glycerin fl.dr. 6 l / 2 Sherry wine, to make fl.oz. 16 Add the acid to 14^ fluidounces of wine, triturate the pepsin with the glyc- erin, gradually add the mixed wine and acid with constant stirring, set aside for 7 days, filter, and add through the filter enough wine to make 16 fluidounces. — Brit. Form. Wine, Quinine. Quinine hydrochlorid gr. 16 Orange wine fl.oz. 16 —Brit. Pharm. Mix, dissolve by agitation, and filter. Wine of Rhubarb, Compound. I. Fluidextract rhubarb fl.dr. 31 Fluidextract Bitter Orange Peel fl.dr. 5 Tincture Cardamom fl.dr. 31 Sugar av.oz. 4^ Sherry wine, q. s., ad fl.oz. 32 Mix the fluidextracts and tincture with 23 fluid ounces sherry wine ; dissolve the sugar in this and add sufficient wine to make the required quantity. — N. F. This is the Compound Wine of Rhu- barb of the N. F. III. II. Rhubarb, coarse powder. . .av.oz. i 1 /^ Canella, coarse powder gr. 50 Sherry wine, to make fl.oz. 16 Mix, macerate for* 7 days, agitating occasionally, strain with expression, fil- ter, and add through the filter enough sherry wine to make the filtrate meas- ure 16 fluidounces. — Brit. Pharm. 1885. Wine of Tar. (Vinum Picis — Tar or Jew's Beer.) I. Pine tar gr. 720 Water fl.oz. 4 Pumice, moderately fine powder av.oz. 2 l /\. Stronger white wine, to make fl.oz. 16 Upon the tar contained in a suitable vessel pour 4 fluidounces of cold water, and triturate the mixture thoroughly; then pour off the water and throw it away. Mix the remaining tar thorough- ly with the powdered pumice, and add, 16 fluidounces of stronger white wine. Stir frequently during 4 hours, then transfer the mixture to a wetted filter, and, after the liquid has passed, pour on enough stronger white wine to make the filtrate measure 16 fluidounces. — N. F. II. Pine tar gr. 720 Magnesium carbonate gr. 180 Sherry wine, to make fl.oz. 16 Mix the tar thoroughly with the mag- nesium carbonate, add the wine, digest the mixture for an hour, filter, and add enough water through the filter to make the filtrate measure 16 fluidounces. — D. C. Form. III. Moore's formula: Pine tar av.oz. 2% Glycerin fl.oz. 1 Sherry wine fl.oz. 1 Honey fl.oz. 1 Acetic acid fl.dr. 1 Water, boiling fl.oz. 12 Mix all the above in a suitable vessel, agitate thoroughly for several minutes, then tightly stopper the vessel and heat on a water bath for an hour or two to a temperature of about 65 or 70 deg. C, shaking frequently. Then set aside in a warm place for a few days, again sha- king frequently, strain through muslin and finally filter the strained liquid. IV. This preparation may also be made from the oil as follows : Oil of tar fl.dr. 2^ Magnesium carbonate gr. 175 Sugar '. av.oz. i*4 Alcohol fl.oz. 2.y 2 Simple syruo fl.oz. i*4 Sherry wine, to make fl.oz. 16 Triturate the oil with the magnesium carbonate and sugar to a smooth mix- ture, then having mixed the alcohol, wine, and water together, rub the tar mixture with this liquid added gradual- ly, filter, and finally add the syrup. Wine of Wafer Ash. (Wine of Ptelea.) A preparation of this kind may be made as follows: Water ash, powder av.oz. 25^ Sherry wine, to make fl.oz. 16 Extract the drug by percolation. 542 STANDARD FORMULARY OF Wine, White, Stronger. White (sherry) wine fl.oz. 7 Alcohol fl.oz. i When tested for alcohol, stronger white wine should contain not less than 20 nor more than 25 per cent, of absolute alcohol by weight, and hence* the white wine should contain from 10 to 12 p. c. of absolute alcohol. If a weaker wine be used more alcohol is necessary to make the stronger wine; if it be strong- er, less is required. — U. S. P. 1880. and U. S. P. 1880. This is used as a menstruum for ma- king some of the wines. Wine of White Ash. (Vinum Fraxini Americana?.) White ash bark... av.oz. Sy 2 Alcohol, Sherry wine, of each, q. s., ad fl.oz. 16 Mix 2 fl. ozs. alcohol with 14 fl. ozs. sherry wine and macerate for 3 days, in a covered vessel; then transfer to a per- colator prepared for percolation and allow the liquid to drain. When com- pletely drained, pack the residue firmly, and gradually pour on the menstruum until the total percolate measures 16 fluidounces. Finally, filter the product, if necessary, and keep it in well-stop- pered bottles, which should be com- pletely filled, and stored in a cool place. Each fluidram represents 30 grains of drug, which is the inner bark of the trunk or root of Fraxinus Americana Linne. — N. F. Wine of Wild Cherry. Wild cherry, No. 40 pow- der av.oz. 4J4 Water fl.oz. 3 Alcohol fl.oz. i l / 2 Sugar av.oz. 2^ Purified talc gr. 120 Sherry wine, to make fl.oz. 16 Moisten the wild cherry with the wa- ter and transfer it to a percolator pre- pared for percolation. Allow the per- colator to remain well covered for 3 or 4 hours, then pack the moistened drug- moderately firm, and pour on enough of a mixture of V/2 fluidounces of alcohol and 10 fluidounces of the wine to leave a stratum above the drug. When the liquid begins to drop, close the lower orifice, and continue the maceration for 12 hours. Then allow percolation to proceed slowly, gradually adding the remainder of the mixture of alcohol and wine, followed by enough wine to make 14^ fluidounces of percolate. In this dissolve the sugar, add the talc, mix thoroughly, then filter, returning the first portions of filtrate to the filter un- til it runs through clear, and finally add enough angelica wine to make the fil- trate measure 16 fluidounces. — N. F. Each fluidram represents 15 grains of wild cherry. Wine of Wild Cherry, Ferrated. Tinct. of iron citrochlorid. .fl.dr. 10 Wine of wild cherry, to make fl.oz. 16 Mix, allow to stand for several days (or a week) if convenient, and filter, if necessary. Each fluidram contains 5 m. of tinc- ture of iron citrochlorid and 13^ gr- of wild cherry. — N. F. Wood Wool. Wood wool is used to some extent in surgical practice in the plain and anti- septic forms. It is a light woolly mass which is capable of absorbing a large quantity of liquid and has the further advantage of cheapness. See next article on sublimated wood wool. Wood Wool, Sublimated. 3/10 p. c. Mercuric chlorid gr. 21 Glvcerin gr. 350 Alcohol fl.oz. 9J4 Distilled water .' fl.oz. 23 Wood wool av.oz. 16 y 2V . c . Mercuric chlorid gr. 35 Glycerin gr. 350 Alcohol fl.oz. 9% Distilled water fl.oz. 23 Wood wool av.oz. 16 Dissolve the mercuric chlorid in the mixed liquids, saturate the wood wool uniformly with all the liquid, and dry at a temperature of 25 to 30 deg. C. — D. PHARMACEUTICAL PREPARATIONS. 543 Wool Fat. (Adeps Lanse.) Wool fat for pharmaceutical and cos- metic purposes is the highly purified fat of sheep's wool. The commercial brands vary considerably in quality, but an al- most odorless, yellowish white product is now obtainable. It appears in the market in the anhy- drous and hydrous forms, the former containing little or no water, the latter containing 30 per cent, of water. Either of these may be prepared from the other. The anhydrous variety may be prepared from the hydrous by heating the latter on a water bath to expel the water. The hydrous kind is to be used in making preparations, compounding prescriptions, etc., unless the hydrous is specified. Both hydrous and anhydrous kinds are. recognized by the U. S., Brit, and Germ. Pharms. In each work the anhydrous kind is known simply as "wool fat," while the other is called "hydrous wool fat." In the Brit. Pharm. it is directed to make the hydrous kind by mixing 3 fluidounces of distilled water with 7 av.- ounces of the anhydrous; the Germ. Pharm. directs mixing 1 part by weight of distilled with 3 parts of anhydrous wool fat ; the U. S. P. does not make mention of such procedure. Part II. DOMESTIC AND VETERINARY REMEDIES. DRUGGISTS' DOMESTIC PREPA- RATIONS. While this Part is not intended in any sense as a treatise upon the manufacture of proprietary medicines, it is proposed to impart to the pharmacist such infor- mation as he requires in preparing rem- edies for ordinary ailments, for popular use and sale. These remedies may be offered by the pharmacist for sale under his own name or that of a pseudonym, if the latter be preferred. Strictly toilet preparations, such as freckle, tan and sunburn removers, hair growers, etc., are mentioned in another Part under "Perfumes and Toilet Arti- cles." Ague Cures. Remedies for the relief and cure of fever, ague, and chills, or, more proper- ly, malaria, are not of such frequent use as they were some years ago; however, there is still a demand in some sections, and the pharmacist must be prepared to supply the want. Most of these rem- edies are made to contain cinchona or one or more of its alkaloids, sometimes also arsenic and frequently some iron or a cathartic. These preparations may assume the form of liquid or pills, or even some other form, but the two mentioned are the most common. They may be en- titled Peruvian Ague Cure, Ague Tonic, Ague Tonic Syrup, Ague Tonic Cure, Chill Cure, Chill Tonic, Ague Pills, Anti- Chill Pills, Cholagogue, Ague Remedy, Ague Bitters, Ague Specific, Fever and Ague Tonic, Febrifuge, Ague Specific, etc. Liquids. The dose of these mentioned here is one or two teaspoon fuls 3 times a day. I. Formula of the Illinois Pharma- ceutical Association : Tincture of eucalyptus (1 in 10) fl.oz. 4' Tincture of serpentaria fl.oz. 8 Tincture of capsicum fl.dr. 10 Tincture of myrrh fl.dr. 10 Tincture of nux vomica fl.dr. 4 Quinine sulfate ..dr. 2 Elixir of licorice, to make.. fl.oz. 2> 2 II. Quinidine sulfate av.oz. 2 Solution of arsenous acid. . .fl.dr. 4 Fluid extract of senna fl.oz. 8 Syrup of licorice, to make.. fl.oz. 64 Owing to the absence from the above of the bitter taste of quinine, cinchoni- dine or cinchona bark, it may be termed Tasteless Chill Cure, Tastless Ague Tonic, or Tasteless Chill Tonic. The fluid extract of senna may be omitted. Powders. III. Cinchona, powder av.oz. 4 Cream of tartar av.oz. 4 Clove, powder av.oz. y 2 The dose is one teaspoonful every 3 hours. This preparation has been termed Dutch Ague Remedy. Pills. IV. Make pills, each containing : Chinoidine gr. 1 Iron ferrocyanid gr. 1 Oil of black pepper drop 1 Arsenous acid gr. 1/20 V. Chinoidin gr. 150 Podophyllin gr. 5 Leptandrin gr. 10 Capsicum powder gr. 20 546 THE STANDARD FORMULARY Ague Cures (Cont'd). Powder the chinoidin, mix with the other ingredients, warm gently to make a mass and divide into ioo pills. For chills and fever, take I to 4 pills, according as they are intended for chil- dren or adults, the dose being repeated every 3 or 4 hours between the chills. These pills are also recommended for neuralgia when the dose for adults is 1 or 2 pills every 2 hours until relieved. These pills are also useful, used as a liver and laxative pill, as may be noted from the ingredients. Asthma Remedies. The number of titles employed to des- ignate asthma remedies is comparatively small ; the following are appropriate : Asthma Remedy, Asthma Elixir, Ant- asthmatic Powder, Antasthmatic Rem- edy, Asthma Cure, Asthma Mixture, etc. Asthma remedies are of about three kinds, one for internal administration, one for inhalation, and one to be ignited, the vapor to be inhaled. Favorite in- gredients of the first kind are the alkali iodids, ammonium salts, grindelia, wild cherry, lobelia, belladonna, Hoffman's anodyne, etc. The liquid preparations for inhalation contain amyl nitrite and oil of mustard. Asthma remedies to be used by ignition are usually composed of stramonium, potassium nitrate, belladonna, etc. Internal Remedies. I. Ammonium iodid gr. 120 Tincture of lobelia fl.dr. 2 Tincture of belladonna fl.dr. 2 Fluid extract of grindelia robusta fl.dr. 4 Fluid extract of licorice. . .fl.dr. 4 Syrup of tolu, to make fl.oz. 4 The dose is a teaspoonful three times a day. Extra doses are to be used dur- ing a paroxysm. II. Potassium iodid gr. 160 Fluid extract of grindelia. fl.dr. 4 Fluid extract of belladonna, .m. 30 Tincture of gelsemium fl.dr. 1 Water fl.oz. 1 Simple elixir, to make fl.oz. 4 The dose is one and a half tcaspoon- fuls every 2 or 3 hours. After about three doses are taken the difficulty of breathing will have disappeared. III. Potassium iodid gr. 160 Tincture of belladonna m. 160 Solution of potassium ar- senite m. 100 Water, to make fl.oz. 4 One teaspoonful is to be given in wa- ter between meals. IV. The following, known as Hare's Antiasthmatic Elixir, is also highly rec- ommended : Sodium iodid gr. 256 Sodium bromid gr. 256 Tincture of lobelia m. 256 Fl. ex. euphorbia pilulif era. fl.dr. 6^2 Spirit of nitroglycerin m. 64 Simple elixir, to make fl.oz. 16 The dose is one or two teaspoonfuls 3 times a day, well diluted in water. Inhalants. V. The following two formulas are for preparations intended as inhalants to relieve the paroxysms of asthma : Oil of mustard, essential. Oil of Scotch pine. Oil of eucalyptus... Oil of peppermint. Tincture of iodin... Ether Alcohol, to make. . . Moisten cotton or mixture and inhale the vapor. VI. Amyl nitrite fl.dr. 2 Oil of mustard, essential. . .drops 10 Ether fl.dr. 4 Alcohol fl.oz. z l / 2 Put a few drops of the liquid upon some cotton or sponge and inhale from the latter. VII. Stramonium leaves av.oz. 1 Belladonna leaves av.oz. 1 Potassium nitrate gr. 72 Opium gr. 30 Mix the drugs in powder. This is to be burned and the vapors inhaled. tial. . . .m. 15 .fl.dr. 2 .fl.dr. 2 .fl.dr. 2 .fl.dr. 2 .fl.dr. 4 .... .fl.oz. 4 sponj ie with the DOMESTIC PREPARATIONS. 47 VIII. Stramonium leaves av.oz. 2 Cannabis indica av.oz. 1 Lobelia leaves av.oz. 1 Eucalyptus ax.oz. 1 Tea leaves av.oz. 1 Anise gr. 60 Potassium nitrate av.oz. iJ4 Reduce all to powder and pass through a No. 30 sieve; then dry thoroughly. If the potassium nitrate be fixed with 3 ounces of water, and the vegetable pow- der be moistened with the solution, and then thoroughly dried, it burns better; but if all the ingredients are well dried, and the niter is thoroughly mixed, this is not necessary. Papers. IX. The Paper of Potassium Nitrate, U. S. P., 1890, may be used. It is pre- pared by immersing strips of white un- sized paper in a solution of potassium nitrate in 4 parts of water, and then dry- ing them. In using they are to be ignited and the vapor inhaled. Cigarettes. X. Cigarettes may be prepared from a mixture of equal parts of stramonium, lobelia and belladonna leaves. These may be cut to a very fine condition, then rolled in suitable paper, and sealing the ends to prevent the drug from falling out by turning up the ends of the paper. XL Another form of cigarette use- ful for asthma is the following: Sodium arsenate gr. 4 Extract of belladonna .gr. 10 Extract of stramonium gr. 10 Mix and dissolve in a small quantity of water or diluted alcohol, with this so- lution saturate a piece of blotting or other bibulous paper large enough to ab- sorb all of the liquid, then dry the paper and cut it into 32 parts. Each of these rolled into cigarette paper makes one cigarette. One of these may be smoked 3 or 4 times a day. 35 Barber's Itch, Remedies for. I. Resorcin gr. 90 Glycerin fl.dr. 4 Water or rose water fl.oz. 1 Lac sulphur av.oz. y 2 Bay rum, to make fl.oz. 4 Apply twice daily by means of a soft sponge. II. Shave off the hairs or cut them very short ; then apply, once or twice a week, an ointment composed of Prepared chalk av.oz. 1 Coal tar gr. 45 to 180 Glycerin fl.dr. 4 Simple cerate av.oz. 5 III. Menthol gr. 60 Yellow oxid of mercury gr. 5 Benzoic acid gr. 20 Camphpr, powder gr. 20 Boracic acid gr. 20 Petrolatum, to make gr. 480 Use freely three or four times a day. Wash the eruption with a 10 per cent solution of carbolic acid before using. IV. The remedies mentioned under Ringworm Application may also be used for barber's itch. Bitters. The preparations known as "bitters" were very much more common some years ago than they are now. To a large extent they are obsolete except in some prohibition districts where they are merely disguised tipples. These bit- ters were recommended for a great va- riety of disorders, including stomach af- fections such as indigestion and dyspep- sia, also malaria, liver and kidney com- plaints, and constipation ; they were also recommended as tonics in enfeebled con- ditions and alteratives in diseased states of the blood. They therefore contained such ingredients as columbo, gentian, cinchona, calamus, aloes, senna, man- drake, culver's root, bitter orange peel, juniper berries, buchu, hops, iron torn- pounds, chamomile, wahoo, cardamom, dandelion, burdock, cinnamon, prickly ash, etc. The directions for taking these prepa- 548 THE STANDARD FORMULARY Bitters (Cont'd). rations is from a tablespoonful to a vvineglassful three times a day. Suitable names for these preparations are Wahoo Bitters, Jaundice Bitters, Stomach Bitters, Hop Bitters, Plantation Bitters, American Plant Bitters, Prickly Ash Bitters, Tonic Bitters, Iron Tonic Bitters, Purgative Bitters, Liver Bitters, German Bitters, Spring Bitters, Burdock Bitters, etc. If the preparation is strong- ly recommended as an alterative or blood purifier it may be called Altera- tive Bitters or Blood Bitters. I. Formula of the Illinois Pharma- ceutical Association: Gentian av.oz. 7 Calamus av.oz. 4 Bitter orange peel av.oz. 2 Tincture of iron citro- chlorid fl.oz. 3 Syrupy glucose fl.oz. 14 Alcohol, water, to make fl.oz. 64 Mix the three drugs, reduce to coarse powder, and extract by percolation with a mixture of 1 volume of alcohol and 2 of water to obtain 47 fluid ounces of percolate; to this add the glucose and tincture. II. Aloes av.oz. 6 Sassafras av.oz. 8 Gentian av.oz. 4 Hops av.oz. 2 Chamomile av.oz. 2 , Acetic acid av.oz. 1 Alcohol fl.oz. 32 Water, to make gal. 1 Mix the acid and alcohol with 2 quarts of water, also mix the drugs, reduce to coarse powder, pack and macerate in a percolator, pass the previous mixture through it, and then enough hot water to make 1 gallon. III. Fluid extract of gentian. . .fl.oz. 1 Fl. ext. yellow cinchona. . . .fl.oz. 1 Quinine sulfate gr. 120 Iron citrate, soluble av.oz. 2 Spirit of orange fl.oz. 1 Simple syrup fl.oz. 32 Water, hot fl.oz. 8 Sherry wine, to make gal. 1 Dissolve the iron salt in the water, add the other ingredients, and filter. IV. Fluid extract of hops fl.oz. 2 Fluid ext. of red cinchona, .fl.oz. 1 Fluid ext. of sarsaparilla. . .fl.dr. 6 Fluid ext. of hydrastis fl.dr. 6 Fluid ext. of mandrake fl.dr. 4 Oil of wintergreen m. 45 Oil of sassafras m. 25 Oil of peppermint m. 15 Oil of lemon m. 15 Sugar av.oz. 12 Alcohol fl.oz. 32 Water, to make gal. 1^ Mix all, dissolve the sugar by agita- tion, let stand a few days, and filter. The drugs may be used instead of the fluid extracts, in which case they are to be extracted with a mixture of 2 vol- umes of alcohol and 9 of water. V. Cascara sagrada av.oz. 4 Gentian av.oz. 4 Dandelion av.oz. 2 German chamomile av.oz. 2 Stillingia av.oz. 2 Bitter orange peel av.oz. 1 Clove gr. 180 Spirit of orange fl.oz. 1 Sugar av.oz. 16 Alcohol, water each, sufficient Mix the seven drugs and reduce to moderately coarse powder, extract by percolation with a mixture of 1 part of alcohol to 3 of water so as to obtain 120 fluidounces of product. To this add the spirit of orange and the sugar; dissolve the latter by agitation. VI. Hops av.oz. 4 Dandelion av.oz. 4 Gentian av.oz. 4 German chamomile av.oz. 4 Stillingia av.oz. 4 Sugar av.oz. 32 Water, alcohol each, sufficient Mix the drugs, reduce to coarse pow- der and extract by percolation so as to obtain no fluidounces of percolate, using a menstruum composed of 1 volume of alcohol and 3 of water ; in this percolate dissolve the sugar by agitation or perco- lation. DOMESTIC PREPARATIONS. 549 VII. Gentian av.oz. 4 Cinchona av.oz. 2 Roman chamomile av.oz. 1 Quassia av.oz. y 2 Bitter orange peel av.oz. y 2 Diluted alcohol gal. 1 Mix the drugs, reduce to coarse pow- der, mix with the diluted alcohol, mace- rate for 7 days, agitating occasionally, then express and filter. "Black Eyes" and Bruises, Applica- tions for. Ammonium chlorid av.oz. */> Alcohol fl.oz. Y A Water fl.oz. 5 Dilute acetic acid may be substituted for one-half the water and the alcohol may be replaced by 1 fluidounce of tinc- ture of arnica. This preparation is a valuable applica- tion for bruises or contusions; it is therefore of value in the treatment of ecchymotic conditions, such as "black eye." If applied at once and continuous- ly for a time after the blow has been received, no discoloration will appear. The following is also useful for bruises and "black eyes" : Potassium nitrate gr. 15 Ammonium chlorid gr. 30 Aromatic vinegar fl.dr. 4 Water, to make fl.oz. 8 Blood Purifiers. These preparations may be put up un- der the names of Sarsaparilla, Sarsapa- rilla Syrup, Compound Extract of Sar- saparilla, Compound Sarsaparilla with Burdock and Iodid of Potassium, Com- pound Syrup of Red Clover Blossoms, Blood Purifying Tea, Alterative Mix- ture, Blood Cleanser, or whatever other title may seem appropriate or desirable. The ingredients of these mixtures are sarsaparilla, stillingia, burdock, yellow dock, red clover, any one or more of these combined, sometimes with potas- sium iodid, often with some laxative. Blood purifying mixtures are in fact mainly cathartics. Sometimes the ca- thartic principle present is a saline like sodium sulfate or rochelle salt, some- times it is senna, mandrake, buckthorn, cascara sagrada, etc. Formerly all blood purifiers were pre- pared in the liquid form: latterly some are prepared in the form of "teas," or species. Examples of both kinds are given among the recipes that follow. The "teas" may be termed Blood Purifying Tea, Sarsaparilla Tea, etc. Liquids. I. Formula of the Illinois Pharma- ceutical Association : Potassium iodid av.oz. 2 gr. 80 Water fl.oz. 8 Fluid extract of burdock root fl.oz. 8 Comp. fl. ext. of sarsaparilla. fl.oz. 32 Syrupy glucose, to make fl.oz. 64 Dissolve the iodid in the water and add the other ingredients. The dose is 1 to 4 teaspoonfuls, according to age, 3 times a day. II. Buckthorn bark av.oz. 20 Rochelle salt av.oz. 8 Potassium bicarbonate av.oz. l / 2 Sugar av.oz. 24 Alcohol fl.oz. 24 Spirit of lemon fl.dr. 6 Tincture of ginger fl.dr. 6 Oil of anise drops 15 Water sufficient With sufficient water make $ T / 2 pints of decoction from the buckthorn bark, which may be deprived of bitterness by the addition of calcined magnesia (see Bitterless Extract of Cascara Sagrada, Part I) and dissolve in it the rochelle salt, potassium bicarbonate and sugar. After allowing to stand for some time, clarify by straining through flannel. Then mix the remaining ingredients and incorporate with the decoction. The dose is from 1 to 2 tablespoonfuls morning and evening, some time after meals. III. Cream < of tartar av.oz. 2 Potassium bicarbonate gr. 600 Fluid extract of mandrake. fl.dr. 4 Comp. fl. ext. of sarsapa- rilla fl.oz. 6 Comp. tincture of carda- mom fl.oz. 1 550 THE STANDARD FORMULARY Blood Purifiers (Cont'd). Glycerin fl.oz. 8 Water, to make fl.oz. 64 Dissolve the two potassium compounds in 8 fluidounces of water by the aid of a gentle heat, add the remaining ingredi- ents, set aside for about 12 hours, and filter. The cream of tartar and potas- sium bicarbonate together form neutral potassium tartar. IV. This preparation may be called Sarsaparilla with Celery. Sarsaparilla Cascara sagjada Dandelion Sassafras Celery seed .... Burdock root . . Red clover .... Gentian Glycerin .av.oz. .av.oz. .av.oz. .av.oz. .av.oz. .av.oz. .av.oz. .av.oz. . av.oz. 3 3 3 3 2 2 2 2 14 Alcohol, water, to make gal. 1 Extract the drugs by maceration or percolation to make 114 fluidounces, us- ing a mixture of 1 volume of alcohol and 5 of water as the menstruum, then add the glycerin. V. Sarsaparilla av.oz. 16 Sassafras bark av.oz. 4 Burdock root av.oz. 3 Dandelion av.oz. 3 Prickly ash bark av.oz. 3 Roman chamomile av.oz. 3 Potassium iodid av.oz. 1 Sodium salicylate av.oz. J / 2 Glycerin fl.oz. 12 Alcohol fl.oz. 24 Water, to make gal. 1 Grind all the drugs to No. 20 powder. Mix the glycerin and alcohol with 2 quarts of water. Macerate 24 hours and percolate. When the liquid has ceased to drop, pour in hot water until a gallon altogether has been obtained. Add the potassium iodid and sodium salicylate and dissolve. If not sufficiently dark to suit, add 1 fluidounce of caramel. Teas. VI. Senna av.oz. 20 Sugar av.oz. 20 Fennel av.oz. 10 Juniper berries av.oz. 6 Celery seed av.oz. 4 Couch grass .' .av.oz. 4' Sassafras av.oz. 4 Caraway av.oz. 2 Rochelle salt av.oz. 8 All should be in coarse powder and should be well mixed. The mixture is cathartic, alterative and diuretic. VII. Senna av.oz. 32 Coriander av.oz. 8 Manna av.oz. 16 Cream of tartar av.oz. i l / 2 Make into a species. Boils and Carbuncles, Treatment for. A boil is an acute inflammation of the deeper layers of the skin and adjacent connective tissues and is due to staphy- lococcus infection by way of the hair follicles. A carbuncle is similar, but is larger and more serious. The method of treatment is very much the same. The old-time method of treatment for boils was to "bring them to a head" by means of repeated applications of hot linseed poultice. However, any hot applications continuously applied will serve the same purpose ; cloths wrung with hot water or, better, hot boric acid solution, will serve well. Instead of any of these, the so- called mother or Hamburg plaster (see formula in Part I) may be used. If the boil is not too far advanced it may pos- sibly be aborted. Various methods of treatment are outlined below. I— A. Salicylic acid dr. 2 Soap plaster av.oz. 2 Lead plaster av.oz. 1 B. Ichthyol av.oz. l / 2 Resin plaster av.oz. l / 2 Lead plaster av.oz. 1 Melt the plasters and incorporate the other ingredients.. These are intended to be applied once or twice daily on a cloth. II. This is another method of treat- ment: Tincture of chlorid of iron.. fl.oz. 1 Solution of potassium arsenite fl.dr. l l / 2 Water, to make fl.oz. 4 Take a teaspoonful after each meal. DOMESTIC PREPARATIONS. 551 Use, locally, camphorated carbolic acid and poultice of linseed meal when there is much inflammation. Also advise small doses of epsom salts to prevent constipa- tion. III. The following formulas are for what is called the modern treatment of boils and carbuncles : A. Chloroform fl.oz. I Oil of clove fl.dr. i^ to 5 Creosote m. 15 to 30 Liniment of camphor fl.oz. 2 B. Mercury salicylate gr. 2 to 5 Salicylic acid gr. 15 to 30 Alcohol av.oz. 1 Water, to make fl.oz. 4 Dissolve the solids in the alcohol and add the water. These are to be used externally only. The affected part is covered with com- presses saturated with either of the above liquids. At the same time one of the following preparations is to be in- jected into the boil or carbuncle. C. Carbolic acid gr. 1 to 3 Sodium salicylate gr. 15 Sodium borate gr. 15 Glycerin m. 30 Chloroform water fl.dr. 2 Mix and dissolve. D. Iodoform gr. 5 to 8 Salol gr. 8 to 15 Carbolic acid gr. 2 Ether fl.dr. ^ to I Alcohol fl.dr. 1 y 2 or 1 Mix and dissolve. This treatment is said to give excellent results and to do away with a more radi- cal surgical operation even in cases of carbuncle. Bunion Cures. The remedies recommended for the re- lief and cure of corns are usually also recommended for the removal of bun- ions. While these remedies often do af- ford relief, the two maladies are almost as distinct as they could possibly be. Corns are inflammations of the skin, whereas bunions are inflammations of the synovial membrane, which connects the great toe with the foot proper. Noth- ing less than surgical operation will ab- solutely and permanently cure bunions. Relief to bunions is often afforded as stated by the application of corn cures, assisted by frequent bathing in hot wa- ter. Frequently anointing with petrola- tum, the application of tincture of iodin or of iodin ointment, or the wearing of a rubber protector will prove beneficial. A warm flaxseed-meal poultice at night often eases a great deal. Shoemaker recommends the following paint : Carbolic acid fl.dr. 2 Tincture of iodin fl.dr. 2 Glycerin fl.dr. 2 To be applied with a camel's hair pen- cil every day. Copper oleate plaster is also advised by the same authority. Painting on of tincture iodin may help by promoting absorption of the exu- dates; 50 per cent ointment of ichthyol with hydrous wool-fat is useful. In case the inflammation becomes too severe, ap- ply Lotion of Lead and Opium (see for- mula in Part I). Burns and Scalds, Applications for. I. In burns and scalds it is of first importance for the relief of pain to pro- tect the part from the air. A great many remedies have been used for this purpose. Besides being protective, they should also be antiseptic, or at least asep- tic. One of the most popular applica- tions is carron oil, made of equal parts of lime water and linseed oil. The ad- dition of carbolic acid, salol or thymol is suggested as in the following : Thymol gr. 75 Raw linseed oil fl.oz. 8 Lime water fl.oz. 8 Dissolve the thymol in the oil, add the water, and shake well. Olive oil or other bland fixed oil may be substituted for the linseed oil, but the latter has the best reputation for this purpose. This mixture is to be applied freely. 552 THE STANDARD FORMULARY Bunion Cures (Cont'd). ■with or without cloths or by means of a cotton pad, whichever may be most con- venient. After a few days, apply zinc oxid ointment or else use the following : Bismuth subnitrate av.oz. I Boric acid .av.oz. Olive oil fl.oz. 2 Wool-fat, hydrous av.oz. 6 II. A saturated solution of picric acid in water applied continuously on cloths has proved of great efficacy in relieving the pain caused by burns and in promot- ing healing. A proprietary preparation now on the market highly advocated for burns is said to be nothing more than an aqueous solution of picric acid. The solution may be applied on thick cloths or a pad of cotton. III. The following preparation, de- vised by the late Charles Rice, is said to be popular in New York: Gelatin av.oz. 15 Glycerin fl.oz. 2 Carbolic acid fl.dr. 2 Water fl.oz. 32 Soak the gelatin in the cold water un- til it is soft, then heat on a water bath until it is dissolved. Add the glycerin and continue heating until a firm, glossy skin begins to form on the surface of the mixture during the intervals between stirring. Now add the carbolic acid and mix well. The mixture may be kept ready pre- pared, and is best preserved in well- closed glass or porcelain jars. When it is wanted for use it is heated on a water bath until just melted and applied with a soft, flat brush over the burned part, where it will form a strong, flexible skin. This preparation is said to be very ef- fective, being superior to carron oil and similar preparations ordinarily used. IV. Unna's burn salve is composed of: Wool-fat, anhydrous part 1 Benzoinated lard parts 2 Lime water parts 3 V. Some of the preparations under the heading Ointments or Salves, may also be utilized. Liniment of Turpen- tine (see formula in Part I) is also used for burns. Canker Sore-Mouth. Canker, also called thrush and spruce, is a disease of infanc3 r , and is due to im- proper feeding and poor digestion. It appears as white spots, of greater or less size, in the mouth and throat. These spots are due to micro-organisms. Can- ker is more common in infants fed on artificial food than in those fed or breast-milk, and in such cases may be accompanied by vomiting, diarrhea, fev- erishness, etc. It will be surmised that the local treatment should be supple- mented by treatment directed towards the removal of the cause. Castor oil to cleanse the intestinal tract and antifer- mentative preparations to prevent fer- mentation of food are in order, also change of diet. For local application the most popular remedy is honey and borax, which is smeared on with a soft cloth or with the ringers or by means of a camel-hair pen- cil, 3 or 4 times a day. A solution of borax in glycerin may also be used as in the following : Borax av.oz. 1 Glycerin fl.oz. 2 Distilled water, to make fl.oz. 8 Infusion of gold thread is also a pop- ular and effective application, though not so pleasant to the child as either of the preceding. If the disease still persists, the spots should be touched occasionally with burnt alum or a piece of copper sulfate or the mouth washed with a weak solu- tion of silver nitrate or zinc sulfate, as follows : Zinc sulfate gr. 5 Rose water fl.oz. 1 Cancer, Local Treatment of. Arsenic is the chief ingredient of most of the local applications recommended for the cure of cancer. Zinc chlorid in solution is also used, as is also a com- DOMESTIC PREPARATIONS. 553 bination of this with arsenic. One of the best known preparations is Mars- den's Cancer Paste. This consists of arsenous acid, two parts, and mucilage of acacia, one part, made into a paste. Its application causes considerable pain and is sometimes replaced by Bougard's paste, which is less painful, forms a more dry and friable slough, can be safely applied to a larger surface and can be kept ready for instant use. With both pastes the surfaces must be denud- ed, if not already ulcerated, by caustic potash, to render the action prompt and effective in the shortest possible time. Bougard's formula is as follows : Wheat flour av.oz. I Starch av.oz. I Arsenic gr. 7 Mercuric sulfid gr. 36 Ammonium chlorid gr. 36 Mercuric chlorid gr. 4 Solution of zinc chlorid. . . .av.oz. 4 The first six substances are separately reduced to fine powder. They are then mixed in a porcelain or glass mortar, and the solution of zinc chlorid slowly poured in, while the contents are kept rapidly rotated with the pestle so that no lump will be formed. A thick layer of this is spread on cotton and left in po- sition 24 hours, and then managed in every way as is Marsden's paste. Few cases require a second application. The ulcer may be dressed with peru balsam or aristol ointment of varying strengths, according to the stimulation required, and all exuberant granulations are to be kept in check by the usual methods. Another local preparation for cancer is Esmarch's Painless Cancer Powder, which is said to contain arsenous acid 10 grains, morphine hydrochlorid 10 grains, calomel 80 grains, acacia 480 grains. Applications of this character should never be made under the direction of in- competent persons. Arsenic as a caustic is not only in its action difficult to regu- late, but dangerous symptoms of poison- ing have resulted from the very ready way in which it is absorbed by the skin. The same remarks apply with equal force to mixtures containing zinc chlorid, tartar emetic and other escharotics. It is the physician's duty to recommend how they shall be used. Catarrh and Cold-in-the-Head, Eem- edies for. The acute form of inflammation of the mucous membrane of the nose is known as coryza or acute rhinitis, the chronic form is called chronic rhinitis or chronic nasal catarrh. In popular parlance the latter is called catarrh, the former cold- in-the-head. Acute rhinitis may lead to bronchitis or to catarrh. Both of these disorders are very common in various parts of the United States. Catarrh, when it has acquired a firm hold on the individual, requires practically constant treatment. The remedies for catarrh are multi- form. Some are snuffs, others are to be used by inhalation, some by spraying, others by insufflation or by injection with syringe or a douche. Others again are in the form of an ointment, which is to be applied to the interior of the nostrils, then to be snuffed up ; and fin- ally* others again are to be taken intern- ally, the latter containing tonics com- bined with some agent which diffuses it- self through the system and thus at- tacks the local manifestations of the dis- ease. The snuffs contain various agents, the most conspicuous being cocaine, the in- discriminate or careless use of which cannot be too severely condemned. Pur- chasers of such snuffs should invariably be warned that the cocaine habit is, of all forms, probably the most horrible, and that great danger attends its use in catarrh snuffs. It should never be rec- ommended in cases of chronic catarrh where its use would be liable to prove continuous. The sale of cocaine snuffs is prohibited by law in many States. The catarrh remedies used by inhala- tion contain either menthol or iodin com- bined with carbolic acid. Those used by 554 THE STANDARD FORMULARY Catarrh Remedies (Cont'd). spraying (with nasal atomizers) contain liquid petrolatum, having in solution menthol, thymol and various antiseptic volatile oils. The catarrh ointments con- tain ingredients similar to those of the preceding. They are usually made with thymol or menthol with some oil, to- gether with boric acid or bismuth salt and petrolatum. Alkaline and antiseptic washes or sprays are also used. Besides the ordinary cold in the head, there is also the similar disorder influ- enza or la grippe. This is a disease of microbic origin, but in its milder forms it seems to the patient nothing more than a cold in the head and is treated similarly. In its severer forms it is so depressing and prostrating that the pa- tient is compelled to go to bed and must have suitable attention from a physician. The preparations for cold-in-the-head are generally in the form of tablets or capsules, sometimes cachets. Usually they are called "cold cures," "anti-grip cures," "coryza tablets," etc. The use of a nose wash like Dobell's or Seiler's So- lution in conjunction with a "cold cure" gives a great deal of relief and comfort. Good titles for catarrh remedies are Catarrh Remedy, Catarrh Cure, Catarrh Snuff, Catarrh Jelly, Cream Balm, Ca- tarrh Balm, Catarrhine, Menthol Snuff, Mentholin, etc. Snuffs. Besides being used for catarrh, it is said that if these preparations are used in the early stages of colds and influenza it will "break them up." I. Menthol gr. 5 Sugar av.oz. 1 Mix and reduce to very fine powder. Use several times daily or as frequent- ly as desired. II. Boric acid, powder av.oz. 1 Sugar, powder av.oz. 4 Menthol gr. 30 Mix and use like the preceding. III. Menthol gr. 5 Sodium bicarbonate gr. 10 Magnesium carbonate gr. 15 Cocaine hydrochlorid gr. 20 Milk sugar av.oz. 1 This is a specimen of a snuff contain- ing cocaine, but its use is not advised. It is beneficial when used in moderation for a short period of time, but its con- tinued use will result in the dreaded co- caine habit. The above mentioned all contain and may be sold as "menthol snuff" or "men- tholin." Some snuffs are intended to produce sneezing. A well-known proprietary ar- ticle of this kind is said to be merely powdered bayberry bark. Other sneeze producing mixtures are the following : IV. A specimen of a bismuth powder is the Anticatarrhal Powder of the N. F. (see formula in Part I). V. Other catarrh snuffs are men- tioned in Volume I under Snuffs. Oil Sprays. These mixtures are intended for spraying into the nose by means of a nasal atomizer. They consist usually of combinations of menthol, thymol, anti- septic volatile oils, etc., dissolved in li- quid petrolatum (paraffin oil). The lat- ter should be of a high grade of purity, such as is now easily obtainable in the market. The menthol, thymol or other solid should be perfectly dissolved as otherwise it will clog the atomizer. VI. Oil of eucalptus drops 80 Carbolic acid gr. 8 Liquid petrolatum fl.oz. 4 To insure perfect solution, use the crystal carbolic acid, not the liquefied. This is useful in all stages of nasal catarrh, including catarrh of grip. It is to be used by spraying several times daily. VII. Eucalyptol m. 15 Terebene m. 15 Menthol gr. 4 DOMESTIC PREPARATIONS. 555 Liquid petrolatum fl.oz. 4 Use like the preceding. VIII. Chloretone gr. 15 Camphor gr. 40 Menthol gr. 40 Oil of cinnamon drops 12 Liquid petrolatum, to make. fl.oz. 4 This is known as McClintock's Chlor- etone Inhalant. It is to be used like the preceding. Aqueous Sprays. These are usually of an alkaline char- acter, sometimes with an antiseptic vola- tile oil or with menthol, dissolved in water with or without alcohol or with glycerin ; or the spray may contain iodin. They are to be used in a nasal atomizer. IX. Examples of this class of sprays are Dobell's or Seller's Solution (see formula in Part I), or Sajou's formula may be used, which is as follows: Sodium bicarbonate gr. 32 Sodium borate gr. 32 Fl. ext. pinus canadensis fl.dn 1 Glycerin fl.oz. 1 Water, to make fl.oz. 4 This is generally diluted with from 2 to 4 parts of water, and is to be used 4 to 6 times daily. X. Here is another example : Menthol gr. 4' Oil of eucalyptus drops 16 Oil of wintergreen drops 16 Sodium bicarbonate gr. 60 Sodium borate gr. 60 Glycerin fl.oz. 1 ^ Water, to make fl.oz. 4 Mix, dissolve and filter. One teaspoonful.is to be mixed with a fluidounce of water before use. XL This is an example of aqueous sprays containing iodin: Iodin gr. 12 Potassium iodid gr. 30 Glycerin fl.oz. 2 Water fl.oz. 2 Use this without dilution. Ointments. Preparations in ointment form for use in nasal catarrh are quite popular. They have the same medicinal ingredients as the ©il sprays which are made into a soft ointment with white petrolatum. They may be dispensed in tin boxes or in collapsible tubes. In using these ointments, introduce a small amount into the nostrils and snuff it up as far as possible. These are ap- plied several times daily. Customary names for these preparations are "ca- tarrh jelly, "catarrh cream," "cream balm" and "catarrh balm." XII. Oil of eucalyptus fl.dr. 2 White petrolatum av.oz. 4 XIII. Thymol gr. 20 Eucalyptol gr. 40 Menthol gr. 40 Bor acid gr. 80 White petrolatum av.oz. 4 Melt the petrolatum at a gentle heat and incorporate the other ingredients. Douches. Various combinations in aqueous form are used either by insufflation (snuffing into the nose from the palm of the hand) or preferably by means of a douche. The latter may be the old-style glass or tin vessel hung on the wall with a rubber tube attached or the more mod- ern all-glass affair of the shape of a wide tube closed at one end, the other end bent and terminating in a stubbed tip with a perforation through which the li- quid flows into the nostrils. In using the former a large amount of liquid is al- lowed to flow through the nostrils, hence greater dilution of the medicating sub- stance is required and, on account of its volume, the liquid must be used luke- warm. The resultant cleansing of the mucous membrane is as beneficial as the contact of the medicating substances. The more modern style of glass douche described above has the advan- tage of being small and readily carried about, and it may be used at any time or place, only a small volume of liquid be- ing required. When used, the requisite amount of medicating solution (usually one or two teaspoonfuls) is put into the douche, and the latter filled about three- 556 THE STANDARD FORMULARY Catarrh Remedies (Cont'd). fourths with water (about one ounce), which is preferably, though not necessar- ily, lukewarm; the open end of the douche is then applied to one of the nos- trils, the head is tipped back when the liquid runs through the nasal cavity; after a minute or two the head to be thrown forward when the excess of li- quid will run back into the douche. The liquids used as douches are any of the preparations mentioned under Aqueous Sprays, or Lister's or Seiler's Antiseptic Solution, Dobell's Solution or Alkaline Antiseptic Solution (see formu- las in Part I), or Sajou's Solution, or the following: XIV. Boric acid gr. 60 Borax gr. 60 Sodium chlorid gr. 30 Lister's antiseptic solu- tion fl.oz. 2 Water fl.oz. 6 Powders. Preparations in powder form for the treatment of catarrh are nearly obso- lete. They were designed to be made into an infusion (extracted) by the patient with water, and the liquid used in a douche. They are composed of such ingredients as golden seal, sodium chlorid, sodium bicarbonate, potassium chlorate, carbolic acid, etc. The follow- ing is an example : XV. Sodium chlorid gr. 240 Potassium chlorate gr. 100 Ammonium iodid gr. 4 Carbolic acid drops 20 Camphor, powder gr. 16 Golden seal, powder gr. 40 Mix well. This is to be treated with water to make an infusion, which latter is then to be used by insufflation or in a douche. Tablets. Tablets for use in nasal catarrh are used to some extent. They are made to contain similar ingredients to the alkaline aqueous sprays or to Seiler's Antiseptic Solution (the so-called Seil- er's Tablets), the sodium bicarbonate, sodium borate, volatile oils, menthol, thymol, eucalyptol, carbolic acid, and other medicating ingredients being mixed and formed into compressed tab- lets. Manufacturing pharmaceutical houses list various combinations of this kind in their catalogues. The follow- ing is also an excellent combination: XVI. Sodium benzoate gr. 1 Guaiacol , m 1 / 10 Hydrastine sulfate or hydrochlorid .gr. 1 / 100 Oil of sassafras, to flavor. Sugar of milk powder to make a 5-gr. tablet. Dissolve one in about one-half fluid- ounce of water and use in a nasal douche. XVII. The following is the com- position of the tablet known as Mur- ray McFarlane's Plasma Nasal Tablet: Sodium chlorid gr. 5 1/2 Sodium sulfate gr. 1 1/2 Sodium phosphate gr. 1/4 Potassium chlorid gr. 2/5 Potassium sulfate gr. 1/4 Potassium phosphate gr. 1/3 Menthol gr. 1/15 This formula is based upon the com- position of the blood. One tablet dis- solved in 2 fluidounces of distilled water has approximately the same composi- tion (except the menthol) and specific gravity as blood serum and hence it is entirely unirritating to the mucous mem- brane and is perfectly adapted for use as a douche or a spray. The menthol is used for its soothing effect. Inhalants. XVIII. Menthol is an excellent agent for treatment of catarrh by inhalation. It is commonly put up in vessels more or less resembling tubes, which may be opened at both ends to permit free circulation of air through the tube when in use, and which may be closed tightly when not in use. DOMESTIC PREPARATIONS. 557 XIX. Camphor dr. 2 Menthol dr. I Carbolic acid, crystal dr. I Ether fl.oz. y 2 Alcohol fl.oz. 2 Rub the camphor, menthol and car- bolic acid together until liquefied, then add the alcohol and ether. This solution is to be dropped upon absorbent cotton contained in a wide- mouth bottle. The vapor is to be in- haled frequently. Internal Treatment. Remedies for the internal treatment of catarrh are intended to contain such ingredients as will diffuse themselves through the system and thus in this indirect way are supposed to attack the disease. The following two formulas are preparations of this kind. However, the internal treatment should always be supplemented by the use of a douche or spray. XX. Potassium iodid dr. 3 Syrup of iron iodid fl.oz. 1 Comp. syrup of sarsapa- rilla fl.oz. 1 Water, to make fl.oz 4 A teaspoonful is to be taken 3 times a day. XXI. Potassium iodid gr. 60 Compound tincture of cardamon fl.oz. 4 Compound tincture of gentian fl.oz. 12 The dose is a tablespoonful 3 times a day. Grip and Cold Bemedies. The number of preparations offered for the cure of "cold-in-the-head" and la grippe, and the number of formulas to make such preparations, are now le- gion. They always contain various antipyretic agents, sometimes also caf- feine, camphor, opium, ipecac, dover's powder, aloin, podophyllin, etc. The mixtures are commonly put up in the form of tablets or capsules, but may also be dispensed in cachets or as pills. XXII. At the onset, a severe cold may usually be aborted by giving a purgative and inducing free perspira- tion. A large dose of castor oil is a suitable purge for children, while a bottle of solution of magnesium citrate acts nicely in adults. To produce -free perspiration the pa- tient should be given a hot foot-bath and well dosed with hot lemonade or ginger tea. He should then be put into a warm bed and well covered with woolen blankets. If the patient is a child the chest should be thoroughly rubbed with hot camphorated oil and enclosed in a warm woolen jacket or covered with layers of heated flannel. Adults require some- thing more stimulating as Oil of turpentine fl.oz. I Camphorated oil fl.oz. 2 A big mustard or linseed meal poul- tice applied to the chest is still more effective. These measures often suffice, but are made more certain in their results by suitable internal remedies. In children who are feverish and restless a simple fever mixture is best, as the follow- ing: Tincture of aconite drops 2 Potassium citrate gn 60 Spirit of nitrous ether fl.oz. 2 Syrup of ipecac .fl.oz. 2 Syrup of orange, to make. . .fl.oz. 2 Give one teaspoonful every hour for four doses to child two years old, then every two hours for several doses or until better. Children of other ages in the same proportion. To abort a cold in an adult, quinine and dover's powder are probably" the most popular remedies. Either of these may be used in connection with the preliminary measures already described in a single 5-grain dose at bedtime. They may often be combined with benefit, as in the following : Extract of belladonna gr. Vs Camphor gr. 1 Quinine sulfate gr. I Dover's powder gr. 2 558 THE STANDARD FORMULARY Grip and Cold Remedies (Cont'd). Make into a capsule, one of which is to be taken every 3 hours. Other combinations are mentioned in the succeeding formulas. In conjunction with a preparation of this kind, it is advisable to use a cleans- ing wash or spray for the nostrils, such as Dobell's, Seiler's or Lister's or Alkaline Antiseptic Solution. XXIII. Podophyllin gr. 12 Dover's powder gr. 120 Acetanilid gr. 120 Extract of cascara gr. 240 Licorice root, powder sufficient Make into 120 capsules or tablets. The dose is one every 2 or 3 hours. XXIV. Quinine sulfate gr. 1/2 Ammonium chlorid gr. 1/2 Camphor gr. 1/2 Opium gr. 1/10 Extract aconite root gr. 1/10 Extract belladonna leaf gr. 1/20 Make into one capsule or tablet. The dose is one every hour or two until relieved, then one every 3 hours. This is useful in the early stages of a bad cold, it serving to check the secre- tion from the nose. Cathartics. The class of remedial substances most commonly in demand partake of the form of cathartics; also called purga- tives, laxatives and aperients. In offer- ing a preparation of this kind for sale, it is customary, as well as advisable, to recommend it for chronic constipa- tion or as a liver invigorator, a blood purifier, a remedy against biliousness or headache, an anti-dyspeptic, etc. This class of pharmacal remedies may take the form of an elixir, syrup, tablet, lozenge, effervescent salt, pill, confection, powder, species, or solution. Elixir or Syrup. These preparations may be known by such titles as Laxative Elixir, Laxative Syrup, Cathartic Elixir, Elixir Cathartic Compound, Cathartic Syrup, etc.; if con- taining figs, they may be called Fig Syrup, Fig Laxative or Fig Laxative Syrup. I. Compound Cathartic Elixir, Com- pound Elixir of Cascara Sagrada, Syrup of Senna, or Aromatic Syrup of Senna may be sold and dispensed as a cathartic preparation if desired. See formulas in Part I under Elixirs and Syrups. II. Senna leaves av.oz. 8 Buckthorn y bark av.oz. 6 Licorice root av.oz. 4 Anise av.oz. 1 Fennel av.oz. 1 Caraway av.oz. J4 Ginger av.oz. ^2 Oil of wintergreen . drops 10 Oil of sassafras drops 10 Rochelle salt av.oz. 4 Sugar av.oz. 16 Alcohol, water, each. .... .sufficient Reduce the drugs to moderately fine powder and extract by percolation with a mixture of I volume of alcohol and 3 of water to obtain 52 fluidounces of opercolate. To this add the salt, sugar and oils, dissolve the solids with occa- sional agitation, and strain. The dose is a tablespoonful 2 or 3 times daily. III. Senna leaves av.oz. 10 Jalap av.oz. 3 Rhubarb av.oz. 2V2 Buckthorn bark av.oz. 1*4 Cinnamon av.oz. J/2 Nutmeg gr. 60 Oil of peppermint fl.dr. I Sugar > av.oz. 32 Alcohol, water, each sufficient Mix the drugs, reduce them to mod- erately fine powder, and extract by percolation with a mixture of 1 vol- ume of alcohol and 3 volumes of water to obtain 44 fluidounces of percolate. In this dissolve the oil and sugar by agitation and then strain. The dose is a tablespoonful 2 or 3 times a day. IV. Fluid extract of rhubarb. . .fl.oz. 1 Fluid extract of senna fl.oz. l l A Fluid extract of buck- thorn fLoz. 2 DOMESTIC PREPARATIONS. 559 ...fl.dr. 4 ...fl.oz. 2 ...fl.oz. 4 ...fl.oz. 4 . . .fl.oz. 16 Oil of peppermint drops io Solution of potassa m. 30 Saccharin gr. 10 Glycerite of licorice fl.dr. 4 Simple elixir, to make fl.oz. 16 Mix, let stand for 24 hours, and filter if necessary. V. Fluid ext. of mandrake. Fluid ext. of dandelion. Aromatic fl. ext. cascara Syrup of licorice Simple syrup, to make . . The adult dose is a tablespoonful once or twice daily. VI. Aromatic fl. ext. of cas- cara fl.oz. Fluid extract of rhubarb. . .fl.oz. Fluid extract of senna fl.oz. Oil of fennel drops Oil of caraway drops Simple syrup, to make fl.oz. 16 Mix the fluid extracts, then add the oils and th* syrup. VII. Klie's formula: Ginger gr. Cinnamon gr. Coriander gr. Caraway gr. Fennel gr. Sweet orange peel gr. 360 Mandrake gr. 480 Anise gr. 480 Senna, Alexandria av.oz \zVa Tartaric acid gr. 480 Alcohol, water, simple syrup, each sufficient All the solid ingredients, except the acid, are mixed and ground for per- colation and are then extracted with a mixture of 1 volume of alcohol and 3 of water by the usual process for fluid extracts so as to obtain 16 fluid- ounces of fluid extract. To this add the tartaric acid, mix well, let stand for 7 days, agitating frequently, then filter, and mix the filtrate with 3 pints of simple syrup. This preparation is an especially suit- able laxative for infants and small chil- dren. The tartaric acid present is no objection; it imparts a pleasant, acidu- lous taste. 120 120 120 120 120 The dose is one teaspoonful for a child one year old. Oil. VIII. A so-called "tasteless" castor oil may be made as follows: Castor oil fl.oz. 16 Oil of wintergreen. m. 20 Oil of cinnamon m. 5 Saccharin gr. 5 Alcohol fl.oz. 1 Dissolve the oils of wintergreen and cinnamon and saccharin in the alco- hol and add to the castor oil. This preparation may be kept bot- tled and sold especially as a laxative for children. It is an excellent method of administering castor oil. This prep- aration is better than an emulsion as castor oil is less purgative in the emul- sified form. Lozenges or Tablets. . IX. Wash some dried prunes (a pound, for instance), place them in a saucepan over a dull fire or on a sand-bath, with just sufficient water to nearly cover them; when they have boiled long enough to become quite soft, and the greater part of the water has been evaporated, allow them to cool, and rub them in a large mortar so as to crush the fruit, but not the kernels. Transfer them to a coarse straining cloth and squeeze the pulp through it. This should be about the consistence of honey. If not, it can be made so by evaporating it over a water bath. Now make a mixture of: Senna, powder av.oz. 4 Sugar, powder av.oz. 4 Jalap, powder av.oz. y 2 Gum arabic, powder av.oz. % Aromatic powder av.oz. % Add sufficient quantity of the prune paste to make a mass and divide into lozenges of convenient size. These may be sprinkled with powdered sugar or else coated with melted chocolate, then sprinkled with sugar. Tamarind pulp may be used instead of the prune pulp, which would probably be an advantage; and the aromatic powder may be omitted if desired. 560 THE STANDARD FORMULARY Cathartics (Cont'd). X. Ext. of senna, powder av.oz. 2 Ext. of licorice, powder. . .av.oz. 2 Sugar, powder . : av.oz. 2 Oil of anise fl.dr. 2.V2 Oil of wintergreen fl.dr. 2}/ Mix well, and make into a mass with water which is to be divided into 80 lozenges which are to be dried before use. The dose is one or two lozenges at night. Pills and Tablets. Formulas for cathartic pills might be given by the score. Every pharmaceu- tical manufacturer lists a great variety of cathartic pills and tablets, some of which are coated with gelatin, chocolate, white sugar, pink sugar, or possibly lav- ender-colored sugar. The formulas for compound cathartic pills, compound lax- ative pills, vegetable cathartic pills, and others are given in Part I. Other form- ulas are given below. Suitable names to use for these pills and tablets when put up for sale are "liver pills (or tablets)," "cathartic pills (or tablets)," "laxative pills," "antibil- ious pills," "vegetable liver pills," "im- proved liver pills," "improved cathartic pills," etc. If the pills are small they may be known as "liver pellets," "little giant liver pills," "little liver granules," "little cathartic pills," "cathartic gran- ules." or some similar title. The dose is generally from one to three at bed- time. One acts as an aperient, two as a laxative, and three as a purgative and chologogue. XI Aloin gr. 10 Podophyllin gr. 10 Capscum gr. 10 Extract of nux vomica gr. 20 Make into 100 pills. XII. Comp. ext. of colocvnth gr. 100 Podophyllin gr. 50 Leptandrin gr. 50 Extract of jalap gr. 50 Extract of henbane gr. 25 Extract of gentian gr. 20 Make into 100 pills. XIII. The following is the com- bination known as Cook's Pills : Socotrine aloes gr. 100 Rhubarb gr. 100 Calomel gr. 50 Soap, powder gr. 50 Make into 100 pills. Species (Teas). These are mixtures of cathartic drugs such as senna leaves and buckthorn bark with licorice root, coriander, anise, fennel, etc., which make the mixture palatable and act as a corrective to the griping action of senna. Manna is some- times added; it adds to the palatability and effectiveness of the mixture. Ro- chelle salt and cream of tartar are also used with the view of increasing the effectiveness of the mixture and also to modify the griping action of the senna. Other substances added are dan- delion, couch grass, elder flowers, juni- per berries, sassafras bark, etc. The ingredients of these "teas" are to be used in a cut or coarsely powdered condition. Senna is used in a cut con- dition; so are licorice root, couch grass, buckthorn bark, etc.; seeds like fennel, anise, coriander, etc., are to be bruised by contusion in a mortar. Names used for these mixtures are "laxative tea," "cathartic tea," "herb tea," "German herb tea," and "blood- purifying tea." XIV. Laxative Species is an excellent preparation. See formula in Part I. XV. . Senna leaves, cut Couch grass, cut Buckthorn bark, cut. Fennel, bruised Directions. — A heaping teaspoonful of species in a half cupful of boiling water, let stand for short time and then strain, this to be taken at bedtime. XVI. Senna leaves, cut av.oz. 10 Sugar av.oz. 10 Fennel, bruised av.oz. 5 Rochelle salt av.oz. 4 .av.oz. 8 .av.oz. 4 .av.oz. 4 DOMESTIC PREPARATIONS. 561 Juniper berries, bruised. . .av.oz. 3 Celery seed av.oz. 2 t Couch grass, cut av.oz. 2 Sassafras bark, cut av.oz. 2 Caraway, bruised av.oz. 1 This mixture is cathartic, alterative and diuretic. Powders. Well-known cathartic powders are compound licorice powder and com- pound jalap powder. See formulas in Part I under Powders. Or use the following : XVII. Jalap, powder av.oz. 2 Bitartrate of potassium av.oz. 2 Sugar, powder av.oz. 12 Oil of orange fl.dr. 2 The dose is one or two teaspoon- fuls. Salts. Salts of various kinds, or mixtures of saline substances, are quite popular laxatives, especially when they are in the effervescent form. Names used for these preparations are Grape Salt, Fruit Salt, Fruit Laxa- tive, Fruit Saline, Effervescent Saline, Saline Laxative, Laxative Salt, Aperient Salt, etc. These mixtures may be converted, if desired, into the granular form by any of the processes described in Part I under Salts, Effervescent. Among the effervescent salts of ca- thartic character mentioned in Part I are Effervescent Magnesium Citrate, Effervescent Magnesium Sulfate, Effer- vescent Sodium Phosphate, Effervescent Sodium Citrotartrate, Effervescent So- dium Sulfate, and Effervescent Carls- bad Salt. The Artificial Carlsbad Salt may also be used. Other saline mix- tures are the following. XVIII. This may be sold in powder or granular form, the latter being pro- duced by any of the processes described under Salts, Effervescent, in Part I. Magnesium sulfate, dried av.oz. 2 Tartaric acid av.oz. 5 Sodium bicarbonate av.oz. 4 Potassium bitartrate av.oz. 4 Sugar, powder av.oz. 4 XIX. Potassium bitartrate av.oz. 10 Sodium bicarbonate av.oz. 6 Rochelle salt av.oz. 4 Tartaric acid av.oz. 1 Oil of lemon m. 40 Oil of orange m. 20 This may be dispensed in powder or granular form as described under Salts, Effervescent. Waters. XX. The following makes an excel- lent artificial bitter water for aperient purposes : Magnesium sulfate av.oz. 10 Sodium sulfate av.oz. 8 Sodium chlorid av.oz. % Potassium sulfate gr. 24 Sodium bicarbonate gr. 144' Diluted sulfuric acid m. 75 Water, to make gal. 1 Dissolve the solids in the water, filter, and then add the acid. When made in this way the liquid will contain a small amount of carbonic acid gas which makes' it somewhat less unpalatable. The dose is a wineglassful at night on retiring or in the morning before breakfast or both night and morning. Chilblains and Frost-Bites, Remedies for Frost-bites are common in cold weather, and especially when it is damp, and attack the portions of the body not well supplied by the circulation, such as the ears, nose, fingers and toes. The acute form of inflammation di- rectly following severe exposure is com- monly known as frost bite and may be so severe as to result in gangrene of the parts; the sub-acute form which persists and appears upon chilling of the surface is called a chilblain. The toes and feet are the portions of the body most commonly attacked by chilblains. The symptons are intense itching after exposure to cold, the part becoming swollen and dark red; in the severer cases, blisters and sometimes ulcers form. 562 THE STANDARD FORMULARY Cathartics (Cont'd). Those individuals who are subject to chilblains should be especially careful of their feet and of the hosiery and shoes they wear. The feet should not be exposed to sudden changes of tem- perature. The hosiery should be woolen, not too thick; it should be thoroughly dry when put on, and changed as soon as damp either from perspiration or from moisture leaking through the shoes. The same pair should not be worn two days in succession without wash- ing or at least without thorough dry- ing. On no account is the hosiery to be allowed to dry on the feet and the practice of putting the feet before the fire is to be condemned. The shoes should not be too light, especially around the ankles. Remedies for chilblains should be both internal and external. Persons sub- ject to chilblains are frequently poorly nourished and malt extract with cod liver oil, iron iodid, hypophospites and other tonics should be used. The proper treatment of frost-bites consists in applying snow or cold water with friction. Under no circumstances should the patient "thaw out" before a fire. Warm drinks may be adminis- tered and if the sensation of cold is severe a mild stimulant may be given such as half a teaspoonful of aromatic spirit of ammonia or a little whisky or brandy. For the immediate relief of the itch- ing chilblains, the best application is warm water. A great variety of local remedies have been recommended for chilblains. The following prescriptions are all highly recommended by their authors : I. Liniment of belladonna fl.dr. 2 Liniment of aconite fl.dr. 1 Carbolic acid m. 6 Flexible collodion fl.dr. 5 This is to be applied with a camel's hair pencil every night. II. Castor oil; Oil of turpentine; Flexible collodion, equal volumes of each. Paint on 2 or 3 times daily. This is said to be effective even when the chilblains are broken. III. Compound tincture of iodin ; Collodion, equal volumes of each. Paint on several times daily. IV. Camphor av.oz. 1^2 Carbolic acid, crystal av.oz. ]/ 2 Tincture of aconite fl.dr. 1 Triturate together until a liquid is obtained, or place the ingredients in a bottle and agitate until solution oc- curs. Direction : Paint with camel's hair pencil or by moistening cloths and apply- ing morning and evening to the affected parts. The above liquid can also be incor- porated with 4 parts of simple cerate so as to form a salve, and this spread on cloth and applied night and morn- ing. V. Resorcin gr. 120 Ichthyol gr. 120 Tannin gr. 120 Water fl.dr. 10 Mix and dissolve. Affix a "shake" label to the bottle. This liquid is to be applied with a camel's hair pencil every night on retiring. In a few minutes the liquid dries into a kind of varnish. This application is highly recommended but its objection is that it causes blacken- ing of the parts which does not go away for some time and in very delicate skins it sometimes produces cracks or fissures which may cause pain. In such cases the author of the above formula recom- mends to use the following which while not so promptly effective, still gives good results : Resorcin av.oz. 1 Gum arabic av.oz. l /z DOMESTIC PREPARATIONS. 563 Talcum, powder av.oz. I Water fl.oz. 2 Use like the preceding. Cholera Remedies. See Diarrhea and Dysentery Reme- dies. Corn Eradicators. Remedies for the removal of corns are very numerous and assume divers forms such as liquid, salve, plasters, etc. One of the most common and most popular is a preparation of col- lodion containing extract of cannabis indica and salicylic acid, sometimes also strong lactic or glacial acetic acid. An- other popular preparation is an ointment or cerate containing about 10 per cent, of salicylic acid. These are usually to be applied for from 3 to 5 nights con- secutively, followed by a hot foot bath, when the corn can be picked out. If this first treatment does not produce satisfactory results, it should be re- peated. Better results are obtained if a hot foot bath be taken preferably with some sodium bicarbonate in the water, before application of the remedy, then scraping or cutting off the cal- loused tissues as far as possible. The variety of corn referred to is what is called a "hard" corn which attacks the top of the toes. "Soft" corns are the kind occurring between the toes and require different treatment. Liquids. « I. Compound Salicylated Collodion is an excellent preparation. See formula in Part I under Collodions. This is to be painted on the corn every night for 3 or 4 nights with a camel's hair pencil, followed by a hot foot bath when the corn can be picked out. If the first treatment does not entirely extract the corn it should be repeated. This and similar preparations should be dispensed in small vials, and the top of the bottle and cork should receive a coating of melted paraffin to prevent evaporation of the ether and alcohol. 36 A small camel's hair pencil should ac- company the bottle. II. Salicylic acid gr. 120 Lactic acid, concentrated. . .gr. 80 Collodion, to make fl.pz. 4 Mix and dissolve. Use like the pre- ceding. III. Extract of cannabis indica, (Squibb's) gr. 30 Salicylic acid gr. 300 Oil of turpentine fl.dr. 2^ Acetic acid, glacial fl.dr. 1 Collodion fl.oz. 5 Mix the first three ingredients inti- mately, add the collodion, dissolve, and then add the acetic acid. Use like No. I. IV. Collodion is not absolutely neces- sary in these mixtures; the following may be used, for example: Common rosin av.oz. y 2 Salicylic acid av.oz. y 2 Extract of cannabis indica (Squibb's) gr. 30 Alcohol fl.oz. iy 2 Ether fl.oz. 2^ Mix all and dissolve by agitation. Salves. V. Salicylic acid av.oz. l / 2 Simple cerate av.oz. 4 Mix well. This is to be applied to the corn on a piece of cloth every night for 3 or 4 nights, then follow with a hot foot bath when the corn may be picked out. VI. Salicylic acid av.oz. 1 Ammonium chlorid av.oz. 1 Acetic acid, glacial fl.dr. 2 Wool fat, hydrous av.oz. 1 White wax av.oz. 1 Lard av.oz 4 Melt the wax, incorporate the lard and wool fat, allow the mixture to cool somewhat, and thoroughly incorporate the other ingredients. Use like the preceding. VII. Caustic soda or potassa av.oz. 1 Water, hot fl.oz. 1 Glycerite of starch av.oz. 2 564 THE STANDARD FORMULARY Corn Remedies (Cont'd). Rub the alkali with the water to a smooth and uniform paste, and grad- ually incorporate the glycerite. In using, spread a little of the salve on the corn, taking care not to get any on the surrounding parts. Cover with a small piece of cloth and allow to remain for from 2 to 4 hours; then soak the foot in warm water. The corn may be extracted after one or two such applications. Plasters. VIII. Dissolve a mixture of 2 drams each of salicylic acid and ordinary or white rosin in 1 fluidounce of ether and pour this solution upon belladonna or opium plaster spread upon moleskin. This may then be cut up into suitable sizes and dispensed in small envelopes. Directions : Apply a small piece of the plaster to the corn, and after 3 or 4 days follow with a hot foot bath. Repeat this treatment one or more times as may be necessary to extract the corn. IX. Salicylic acid av.oz. 1 Soap plaster av.oz. 6 Melt the plaster, add the acid, and stir frequently until cool. This is to be spread upon strong cloth, thin leather or any material suitable for a plaster. This is to be used like the preced- ing. For Soft Corns. X. The remedies previously men- tioned will prove of more benefit to "hard" corns than to "soft" corns. It has been recommended to treat the lat- ter by painting with a solution of silver nitrate in 8 parts of distilled water every fourth or fifth day, in the mean- time keeping the toes apart by means of a pledget of cotton smeared with petrolatum, zinc ointment or other bland fatty substance. The cure or removal of corns is facili- tated by frequent washing of the feet, followed by removal of all dead tissue. Dry tannin placed between the toes where the corn is located is also rec- ommended as a cure for "soft" corns. Coughs and Colds, Remedies for. Suggested titles for these remedies are Cough Remedy, Cough Mixture, Cough Syrup, Syrup of Tar and Wild Cherrv. Children's Cough Cure, or Baby or Infant Cough Syrup (if intended for small children exclusively), White Pine Syrup, Honey of Hoarhound and Tar, Tar, Tolu and Wild Cherry, Tar and Hoarhound Cough Syrup, Lung Balsam, Expectorant,. Cough Cordial, Cough Bal- sam, etc. Opium in some form or a salt cr derivative of morphine are constitu- ents of almost every cough mixture. This should not be administered to small children or infants and hence it may be advisable to have two prepara- tions, one without morphine, codeine, heroin or opium, or with only paregoric. Other remedies are noticed under the head of Remedies for Throat Affections and under Gargles. The dose of all these preparations is a teaspoonful every 2 or 3 hours, children in proportion, unless the ar- ticle is made for small children ex- clusively. Brown Mixture. This is an excellent preparation for coughs and colds. The formula is in Part I under Mixtures, or the fol- lowing, known as Improved Brown Mixture, may be used : I. Extract of licorice, puri- fied av.oz. 2 Ammonium chlorid av.oz. 2 Paregoric fl.oz. 2 Wine of antimony fl.oz. 1 Spirit of nitrous ether fl.dr. 4 Syrupy glucose av.oz. 20 Water, to make fl.oz. 32 Mix all and dissolve. Dose, 1 to 2 teaspoonfuls every 2 to 4 hours. Two fluidounces of glycerite of lic- orice may be used for the extract and DOMESTIC PREPARATIONS. 565 the glucose may be replaced by simple syrup. Compound . Elixir of Licorice is a similar preparation in elixir form. See formula in Part I under Elixirs. II. Compound Syrup of White Pine: This preparation is also known as White Pine Expectorant and White Pine Balsam. The excellent formula of the N. F. is in Part I under Syrups. This preparation contains 4 grains of morphine sulfate in a pint (1/32 gr.) to the fluidram. The preparations of the market usually contain 3 grains of mor- phine, in the form of acetate, to the pint. The morphine may be omitted or it may be replaced by 3 grains of codeine sul- fate or phosphate to the pint or 2 or 4 grains of heroin hydrochlorid to the pint (1/64 or 1/32 gr. to the fluidram) ; or a small amount of ammonium chlorid or syrup or glycerite of tar may be added. The N. F. menstruum for extraction of the drugs is a mixture of 1 volume of alcohol and 3 of water but it has been claimed that an equally effective menstruum is a mixture of 1 volume of glycerin and 2 of water. Another method of making compound syrup of white pine is the following : Tincture of pine gum fl.oz 8 Fluid extract of ipecac fl.oz. 2 Chloroform fl.dr. 4 Morphine sulfate gr. 32 Magnesium carbonate. ... .av.oz. 2 Sugar av.oz. 48 Water, to make fl.oz. 64 Rub the magnesium carbonate in a mortar with tincture and fluid extract until well mixed, then triturate with 24 fluidounces of water, gradually added, filter, and through the filter add enough water to make 34 fluidounces of filtrate. To the latter add the chloroform, mor- phine and sugar, dissolve by agitation, and strain. The tincture of pine gum is made from 1 av. ounce of gum turpentine and 7 fluidounces of alcohol, agitating occasionally till the gum is dissolved. III. Syrup of White Pine and Tar Comp. : Tartar emetic gr. 16 Ammonium chlorid av.oz. 2 Water fl.oz. 10 Glycerite of tar fl.oz. 2 Syrup of squill . . . . fl.oz. 16 Comp. syrup of white pine, to make gal. 1 Dissolve the tartar emetic and am- monium chlorid in the water and add the other ingredients. IV. Syrup of Tar and Wild Cherry: This popular preparation may be made in various ways, as follows : A. Wild cherry, ground av.oz. 16 Pine tar av.oz 2 Morphine sulfate gr. 16 Sugar av.lb. 5 Water sufficient Moisten the wild cherry with water, pack in a percolator, and let stand over night. Wash the tar with some cold water, then, pour on 80 fluidounces of boiling water and let stand for 24 hours, stirring occasionally. With this water percolate the drug so as to ob- tain 80 fluidounces of liquid. In this dissolve the sugar and morphine by agitation, and strain. B, Ammonium chlorid av.oz. 8 Morphine sulfate ....gr. 16 Water fl.oz. 16 Comp. syrup of squill fl.oz. 12 Syrup of tolu • fl.oz. 16 Syrup of tar fl.oz. 24 Syrup of wild cherry fl.oz. 60 Mix all, dissolve the solids by agita- tion and strain if necessary. C. Fluid extract of ipecac fl.dr. 4 Fluid extract of lobelia fl.dr. 6 Tincture of opium fl.oz. 6 Vinegar of squill fl.oz. 10 Sugar av.oz. 12 Syrup of wild cherry av.oz. 44 Syrup of tar fl.oz. 60 Mix the fluid extracts, tincture and vinegar, let stand for 24 hours, filter, and in the filtrate dissolve the sugar by agitation. To the solution add the syrups. $66 THE STANDARD FORMULARY Coughs and Colds (Cont'd). D. Oil of tar fl.oz. I Magnesium carbonate av.oz. 2 Tincture of opium fl.oz. 4 Fluid extract of ipecac fl.oz. 4 Fluid extract wild cherry. . .fl.oz 6 Water fl.oz. 64 Sugar av.lb. 6 Rub the oil thoroughly with the mag- nesium carbonate, add the fluid extracts and water, mix well, filter, add the tincture and sugar to the filtrate dis- solve the latter by agitation and strain. V.,Comp. Syrup of Wild Cherry: Wild cherry av.oz. 16 Spikenard av.oz 4 Ipecac av.oz. 1 Bloodroot av.oz. 1 Tincture of opium fl.oz. 4 Sugar av.lb. 5 Alcohol, water, each, to make gal. 1 Mix the drugs in a ground condi- tion and extract by percolation with a mixture of 1 volume of alcohol and 3 of water, so as to obtain 72 fluidounces of percolate. To this add the tincture of opium and sugar, dissolve the latter by agitation and strain. VI. Syrup of Wild Cherry and Hoar- hound : Wild cherry, ground av.oz. 20 Hoarhound av.oz. 8 Glycerin fl.oz. 8 Alcohol fl.oz. 8 Sugar av.lb. s T A Water, to make gal. 1 Mix the glycerin and alcohol with 64 fluidounces of water; moisten the wild cherry and hoarhound with 16 fluidounces of this mixture, pack in a clyindrical percolator tightly covered; after 24 hours' maceration proceed with percolation, using the remainder of the menstruum, and afterward sufficient water to make 72 fluidounces of perco- late; in this dissolve the sugar by agita- tion, without heat, and strain. VII. Honey of Hoarhound and Tar : Oil of tar fl.dr. 4 Oil of anise drops 2 Magnesium carbonate dr. 2 Fl. ext. of hoarhound fl.oz. 2 Rum fl.oz. 16 Water fl.oz. 16 Honey, to make fl.oz. 64 Triturate the oils of tar and anise with the magnesium carbonate until well mixed, then incorporate the fluid extract, water and rum, let stand for 24 hours, and filter. To the filtrate add the honey. VIII. Honey and Tolu: Tincture of tolu fl.oz. 2 Paregoric fl.oz. 8 Syrup of squill fl.oz. 8 Honey, to make fl.oz. 64 IX. • Chlorodyne Cough Cure : This is a green, turbid mixture con- taining cannabis indica. Tincture of cannabis fl.oz. I Tincture of tolu fl.oz 2 Fluid extract of lobelia fl.oz. 1 Chloroform fl.dr. 4 Morphine sulfate gr. 16 Tartar emetic gr. 16 Water fl.oz. 2 Spirit of peppermint m. 40 Simple syrup fl.oz. 60 Dissolve the morphine and tartar emetic in the water; mix the tinctures, fluid extract, spirit and chloroform, shake well, add the aqueous solution pre- viously prepared and the syrup and mix thoroughly by vigorous agitation. - This is to be well shaken before use. X. Yerba Santa Cough Mixture or Compound Syrup of Yerba Santa : Yerba santa Grindelia , Wild cherry , Licorice root , Ammonium bromid Pine tar . . . .av.oz. 2 . . . .av.oz. 1 . . . .av.oz. 1 .... av.oz. I ....av.oz. I . . . .av.oz. Yi Sugar av.oz. 16 Glvcerin fl.oz. 4 Alcohol, water, each sufficient Mix the four drugs, reduce them to coarse powder and extract in the usual way by percolation, using first a mem- struum of the glycerin and 8 fluidounces each of alcohol and water and then followed by diluted alcohol until 22 fluidounces of percolate are obtained. To this add the ammonium bromid and tar, macerate a few hours, agitating occasionally, filter, and in the filtrate DOMESTIC PREPARATIONS. 567 dissolve the sugar by agitation and strain if necessary. XL The following may be sold as a "flaxseed or linseed cough syrup or balsam" : Raw linseed oil fl.oz. 4 Oil of cinnamon fl.dr. 1 Oil of wintergreen fl.dr. 1 Oil of sassafras fl.dr. 1 Acacia, powder av.oz. 1 Mucilage of Irish moss fl.oz. 4 Glycerin fl.oz. 2 Simple syrup fl.oz. 5 Morphine sulfate gr. 4 Chloral hydrate . . . . av,oz. 1 Diluted hydrocyanic acid. . .fl.dr. 1 Water, to make fl.oz. 32 Make an emulsion of the four oils with the acacia, mucilage and a por- tion of the water, add the glycerin and syrup, dissolve the morphine and chloral in the remainder of the water and add this solution and the acid to the emul- sion. The morphine and chloral or either of them may be omitted if desired; and the mucilage of Irish moss may be replaced by an equivalent amount of powdered acacia. Emulsion of Linseed Oil, Part I, is a similar preparation and may be used for the above. XII. "C. C" Cough Mixture: This is used in a Philadelphia hos- pital. Codeine sulfate gr. 16 Diluted hydrocyanic acid. . .fl.dr. 4^ Spirit of chloroform fl.oz. 4 Mucilage of acacia fl.oz. 4 Syrup of wild cherry, to make fl.oz. 16 XIII. This preparation is known as Davis' Cough Mixture: Ammonium chlorid gr. 720 Tartar emetic gr. 8 Morphine sulfate gr. 12 Syrup of licorice fl.oz. 16 XIV. This is said to be the original prescription for Dr. Hartshorne's Cough Mixture : Compound spirit of ether fl.oz. 3 Solution of morphine sulfate (gr. to 1 oz.) fl.oz. 3 Camphor water. ,fl,oz, z l A Mucilage of acacia fl.oz. 3^2 Syrup of squill fl.oz. 4 XV. Fothergill's Hydrobromic Acid Cough Mixture: Spirit of chloroform m. 20 Hydrobromic acid m. 30 Syrup of squill fl.dr. 1 Water, to make fl.oz. 1 This is one adult dose, to be taken 3 times a day; for children, the dose is to be reduced according to age. XVI. Dr. Wood's Lemon Juice Cough Mixture : Potassium citrate gr. 60 Lemon juice fl.dr. 2 Syrup of ipecac fl.dr. 4 Simple syrup, to make fl.oz. 6 The dose is a tablespoonful 4 to 6 times a day. XVII. Dr. Child's Cough Mixture : Wine of ipecac fl.oz. 1 Paragoric fl.oz. 1 Syruo of squill fl.oz. 2 Simple syrup fl.oz. 4 Water fl.oz. 24 Cough and Cold Mixtures for Small Children. Many of the above mentioned cough and cold mixtures contain morphine, cannabis indica or other substance that would forbid their administration to infants and small children and hence it is customary, or at least advisable, to have a cough and cold remedy for adults and older children and another one for infants and small children. Of the above mentioned formulas, Nos. I, II (if made without opiates), VI, VII, VIII, X or XI may be recommended for small children. The following prep- arations may be called Children's Cough Cure, Baby Cough Syrup, Infant Cough Mixture or other similar appropriate name. The usual dose for a child 2 or 3 years old is one teaspoonful every 2 or 3 hours. XVIII. Ammonium chlorid av.oz. 2 Chloroform fl.dr. 3 Syrup of ipecac fl.oz. 1 Syrup of tolu ■> fl.oz, 10 Syrup of licorice, to make. . .fl.oz, 64 Mix and dissolve. 568 THE STANDARD FORMULARY Coughs and Colds (Cont'd). XIX. Ammonium chlorid av.oz. 2 Comp. syrup of squill fl.oz. 4 Syrup of tolu fl.oz. 4 Syrup of ipecac fl.oz. 8 Paregoric fl.oz. 6 Water fl.oz. 8 Simple syrup, to make fl.oz. 64 Dissolve the ammonium chlorid in the water, and add the other ingred- ients. XX. Besides the cough and cold preparations already mentioned as be- ing in Part I, that portion of this work also contains formulas for Pectoral Syrup (see formula under Syrups) and Stokes' Expectorant Mixture (sec formula under Mixtures). The following is also an excellent preparation : Wild cherry av.oz. 4 Licorice root av.oz. 2 Herbane leaves av.oz. 2 Anise seed av.oz. i x / 2 Bloodroot av.oz y 2 Chloroform m. 30 Ammonium chlorid av.oz. 1 Sugar av.oz. 32 Alcohol, water, to make fl.oz. 64 Reduce the five drugs to coarse pow- der and extract by percolation with a mixture of 1 volume of alcohol and 4 oz. water to obtain 44 fluidounces of percolate. In this dissolve the sugar and ammonium chlorid by agitation, strain, and add the chloroform. As may be observed this preparation is free from opiates. Cough (Whooping) Remedies. I. Butyl-chloral hydrate gn 15 Potassium bromid gr. 60 Ether drops 25 Tincture of belladonna drops 15 Tincture of henbane drops 25 Syrup of tolu, to make fl.oz. 4 Mix well. The dose for a child two years is a teaspoonful every 2 or 3 hours. II. Bromof orm m. 30 Tincture of tolu fl.dr. 1 Mucilage of acacia fl.dr, 2 Simple syrup fl.dr. 4 Peppermint water, to make. fl.oz. 4 Place the mucilage in the bottle, add an equal volume of syrup, then the bromoform and tincture in portions, shaking well after each addition. Then add the remainder of the syrup and the water, shaking thoroughly meanwhile. Bromoform is a very heavy liquid and from any ordinary mixture it sepa- rates very quickly. The above is a thin emulsion which separates but retains the bromoform in suspension. It should be shaken before use. The dose for a child one year old is one teaspoonful 3 to 5 times daily. Cider chilren require larger doses or the amount of bromoform and mucilage in the mixture may be increased. III. Formaldehyde in 1 per cent, solution as a spray or as direct applica- tion in 5 per cent, solution to the pharynx is highly recommended. For- maldehyde in vapor form is recom- mended by the Health Department of Chicago. IV. Ether fl.dr. 12 Chloroform fl.dr. 6 Oil of turpentine fl.dr. 2 This is to be used as an inhalation during the paroxyms of coughing. It is to be sprinkled upon a cloth or sponge and held to the nose. Croup (Catarrhal Laryngitis) Reme- dies. I. The spasmodic attacks of croup occur at night. The usual method of treatment is to give an emetic such as wine of antimony, syrup of ipecac, or turpeth mineral. Another method of treatment is by means of sedatives, such as the following: Chloral hydrate gr. 80 Potassium bromid gr. 40 Ammonium bromid gr. 32 Cinnamon water, to make. . .fl.oz. 2 This may be made more palatable by substituting syrup of cinnamon for a portion of the water, or else adding a few drops of chloroform. DOMESTIC PREPARATIONS. 569 One tea'spoonful is the dose, to be repeated in 20 minutes, if not relieved. This is intended for a child about 5 years old. Older children require larger doses, younger children smaller ones. The chloral relieves the spasms of the larynx, and the bromid allays the nervousness so that the patient is soon asleep, awakening in the morning as well as usual; there is also little dan- ger of an attack the next night. II. This is for a so-called "croupy" cough : Tartar emetic gr. I or 2 Fluid extract of ipecac m. 30 Fluid extract of senega fl.dr. 2 Syrup of squill fl.oz. 1 Simple syrup, to make fl.oz. 4 The dose for a child 3 years old is a teaspoonful every 3 hours. IV. An excellent external applica- tion for croup is Compound Liniment of Stillingia. For the formula see Lini- ments in Part I. Diarrhea and Dysentery, Bemedies for. These preparations may be put un- der the title Blackberry Balsam, Black- berry Cordial, Blackberry Elixir, Diar- rhea Cordial, Diarrhea Cure, Carmina- tive, etc. The ingredients of these preparations number among the following: Black- berry root bark, blackberry juice, rhu- barb, nutgall, witchhazel bark, catechu, kino, peppermint, opium, capsicum, gin- ger, aromatics and syrups. The black- berry juice and syrup are introduced for the purpose of disguising the styptic taste of the blackberry root bark, nut- gall or other astringent. This is also one object of employing the aromatics, these latter also serving as carminatives. Capsicum is introduced with the view of utilizing its stimulant properties. Opium should be introduced with some N misgiv- ings, for, as a rule, these "cordials" or "balsams" are given to children. In fact, it may be advisable to have two prepara- tions, one containing opium and intend- ed for older children and adults, the other, without opium, for infants and younger children. I. Among the preparations mentioned in Part I which are excellent remedies for the treatment of cholera and diar- rhea are Compound Elixir of Blackberry and Compound Elixir of Dewberry (formulas under Elixirs), Aromatic Syrup of Blackberry (formula under Syrups), Chlorodyne, Cholera Mixtures (formulas under Mixtures), and Dalby's Carminative and Mixture of Magnesia and Asafetida or Dewee's Carminative (formulas under Mixtures). II. This is the diarrhea tablet advised by the Cincinnati Board of Health : Opium gr. 1/4 Camphor gr. 1/4 Ipecac. gr. 1/8 Lead acetate gr. 1/6 For one tablet. III. This is the formula for Dr. Norman Gay's Diarrhea Tablet : Mercury with chalk gr. 1/10 Opium gr. 2/5 Kino gr. 4/5 Camphor gr. 4/5 Aromatic powder gr. 4/5 Bismuth subnitrate gr. 4/5 Sodium bicarbonate gr. 4/5 Blackberry Balsam or Cordial. The following are formulas for this favorite diarrhea remedy. Another formula is in Part I under Compound Elixir of Blackberry (see Elixirs). If the preparation contains ginger, it may be known as Blackberry Cordial or Bal- sam with Ginger or Compound Cordial of Blackberry and Ginger. The dose for an adult is a tablespoon- ful, repeated every 1, 2 or 3 hours as necessary; children in proportion. IV. Blackberry juice fl.oz. 32 Catechu av.oz. 2 Cinnamon av.oz. ^2 Nutmeg av.oz. y 2 Coriander av.oz. l / 2 Opium dr. 1 Sugar av.oz. 16 Alcohol fl.oz. 20 Simple syrup, to make. . . . , .fl.oz. 64 570 THE STANDARD FORMULARY Diarrhea Bemedies (Cont'd). Reduce the drugs to fine powder, mac- erate with the juice and alcohol for 7 days, agitating frequently, filter, in the filtrate dissolve the sugar, and then add simple syrup to make 64 fluidounces. V. Blackberry root bark av.oz. 2 Cinnamon, Saigon av.oz. 2 Nutgall av.oz. 2 Ginger, African dr. 2 Clove dr. 2 Mace dr. 2 Sugar av.oz. 32 Blackberry juice fl.oz. 28 Alcohol fl.oz. 20 Mix the six drugs, reduce them to coarse powder, extract in the usual way by percolation with a mixture of the juice and alcohol, and in the percolate dissolve the sugar by agitation. VI. Fluid extract of blackberry root fl.oz. 2 Tincture of ginger fl.oz. 2 Tincture of opium fl.oz. 2 Tincture of catechu fl.oz. 2 Tincture of kino fl.oz. 2 Tincture of capsicum fl.dr. 4 Sugar av.oz. 4 Alcohol fl.oz 18 Water, to make fl.oz. 64 Mix all, dissolve the sugar by agita- tion and strain. Extract or Essence of Jamaica Ginger This preparation has been and is to some extent a popular favorite for mild forms of diarrhea and summer com- plaint. It is also used as a quick stimu- lant for cramps due to any cause, colic, chills, etc., and for flatulency and dys- pepsia. It is advised to put a few drops into the drinking water in summer time to prevent bowel complaints. The fol- lowing are excellent formulas. The first is a plain tincture, the second is aroma- tized. Both are stronger than the U. S. P. tincture. VII. Jamaica ginger, moderately fine powder av.oz, 24 Alcohol, to make fl.oz. 64 Extract the drug in the usual manner by percolation. VIII. Formula of the Illinois Phar- maceutical Association : Ginger, unbleached av.oz. 16 Calamus av.oz. 1 Canada snakeroot av.oz. 1 Cinnamon dr. 2 Mace dr. 2 Clove dr. 2 Alcohol, to make fl.oz. 64 Mix the drugs, reduce them to moder- ately fine powder, and extract in the us- ual way by percolation. Diarrhea Mixtures for Infants. Infantile diarrhea occurs in children between 6 months and 2 years of age. It is due generally to teething and im- proper feeding. Poor or partly decom- posed milk, unclean dishes, nursing bot- tles with long tubes and unhygienic sur- roundings will, in summer time, quickly cause diarrhea in infants, popularly call- ed "summer complaint." The best treat- ment consists of combinations of mild alkalies, like prepared chalk, combined with bismuth subnitrate or subcarbonate, mild antiseptics like Lister's Antiseptic Solution, benzonaphthol, zinc sufocarbo- late, etc., and usually also with rhubarb and with astringents like kino, catechu or rhatany. Chalk Mixture is used (see formula in Part I), but is usually com- bined with other substances, or use the following : IX. Bismuth salicylate dr. 4 Glycerin fl.dr. 2 Listers' antiseptic solution. . .fl.dr. 4' Chalk mixture, to make fl.oz. 4 The dose is one teaspoonful every 2 or 3 hours as may be necessary. X. Tincture of catechu or kino.. fl.dr. 2 Fluid extract of rhubarb fl.dr. 2 Compound chalk powder dr. 4 Bismuth subnitrate dr. 2 Glycerin fl.oz. 1 Cinnamon water, to make fl.oz. 4 The glycerin preserves the mixture for an indefinite period of time. The dose for a child one year old is a teaspoonful every half, one or two hours according to the severity of the symp- toms. DOMESTIC PREPARATIONS. 571 For Dysentery. Dysentery is an inflammatory disease of the large intestine, characterized by the frequent passage of stools containing blood and mucus. It frequently follows ordinary diarrhea. In cases of a catarrhal type that tend to linger, an excellent remedy is Acid Camphor Mixture, better known as Hope's Camphor Mixture (see formula in Part I under Mixtures). The dose is a tablespoonful or two every 2 hours. The intense pains may be relieved by Chlorodyne. Other useful combinations are the following: XI. Deodorized tincture opium. . .fl.dr. 2 Diluted sulfuric acid fl.dr. 2 Comp. tincture cardamom. . .fl.oz. i l /t Camphor water, to make fl.oz. 6 The dose is a tablespoonful, undiluted, every 3 hours. XII. Calomel gr. 1/8 Camphor gr. 1/16 Morphine sulfate gr. 1/16 Capsicum .... gr. 1/16 Ipecac gr. 1/32 For one tablet. The dose is one every hour, or in ur- gent cases every half hour, until the character of the discharge is improved. Carminative or "Gripe" Mixtures for Infants. The mixtures mentioned under this heading are used for griping (wind colic or flatulence) and for mild cases of diarrhea in infants. The dose of these is about a teaspoonful for a child one year old. The carminatives mentioned in Part I are Dewee's Carminative (see Mixture of Magnesia and Asafe- tida) and Dalby's Carminative (see Mix- ture, Carminative) ; also Compound Powder of Rhubarb and Anisated Pow- der of Rhubarb and Magnesia (see for- mulas under Powders in Part I). The dose of these powders is also about half a teaspoonful to a child one year old, Compound Syrup of Rhubarb and Potassium or Neutralizing Cordial (see formula in Part I under Syrups) is good for the same purpose, as is also the following: XIII. This is called Paris' Carmina- tive Mixture: Calcined magnesia av.oz. 1 Comp. tincture lavender fl.oz. 1 Peppermint water fl.oz. 4 Syrup of ginger fl.oz. 4 Spirit of caraway (1 in 30).. fl.oz. 7 The dose is one-half teaspoonful to a child one year old. XIV. This preparation has been call- ed "Pain Dispeller" and is useful for cramps, diarrhea, etc., in doses of one- half to one teaspoonful: Aromatic spirit of am- monia fl.oz. 1 Compound spirit of ether fl.oz. 1 Spirit of peppermint fl.oz. 1 Spirit of camphor fl.oz. 1 Comp. tincture of lavender, .fl.oz. 1 Tincture of capsicum fl.oz. 1 Tincture of opium fl.oz. 1 Tincture of rhubarb fl.oz. 1 Alcohol fl.oz. 3 Water fl.oz. 5 Dyspepsia and Indigestion, Remedies for. Owing to the prevalence of dyspepsia, remedies for this complaint are in con- siderable demand. Most of the "bitters" and the liver remedies, and many of the blood purifiers are usually recommended for dyspepsia. The remedies recommended especially for dyspepsia contain some stomachic tonic like golden seal, columbo, gentian bitter orange, etc., combined with a lax- ative like aloes, sodium phosphate, rhu- barb, etc.; sometimes an alkali like so- dium bicarbonate, as well as a carmina- tive or stimulant like peppermint, capsi- cum, elixir, etc. I. Fl. ext. of bitter orange fl.dr. 10 Fluid ext. of rhubarb fl.dr. 5 Fluid ext. of columbo fl.dr. 5 Fluid ext. of chamomile fl.dr. 5 Fluid ext. of life everlast- ing fl.dr. 5 Sodium phosphate av.oz. 2 Water, hot fl.oz, 8 Simple elixir, to make fl.oz. 64 572 THE STANDARD FORMULARY Dyspepsia Remedies (Cont'd). Mix the fluid extracts with a portion of the elixir, dissolve the sodium salt in the water, add to the previous mixture, then incorporate the remainder of the elixir, and filter. The dose is a teaspoonful 3 times a day. II. Rhubarb " av.oz. 3 Peppermint av.oz. 3 Potassium carbonate av.oz. . 1 Golden seal av.oz. % Cape aloes gr. 60 Capsicum gr. 15 Sugar av.oz. 24 Alcohol, water, each sufficient Mix the rhubarb, golden seal, aloes, peppermint and capsicum, reduce to coarse powder, extract by percolation with a mixture of 3 volumes of alcohol and 10 of water, so as to obtain 50 fluid- ounces of percolate, having first dis- solved the potassium carbonate in the water. In the percolate dissolve the su- gar, either by agitation or percolation, and then add enough more of the men- struum to make 64 fluidounces. The dose is a teaspoonful 3 times a day. III. Sodium bicarbonate av.oz. r Sodium sulfate av.oz. 2 Comp. tincture of gentian, .fl.oz. 4 Fluid extract of senna fl.dr. 2 Fluid extract of rhubarb. . .fl.dr. 4 Oil of caraway drops 20 Water, to make fl.oz. 16 Dissolve the sodium sulfate and bicar- bonate in the water, add the oil of cara- way to the tincture and fluid extracts and mix together. The dose is a table- spoonful after meals and at bedtime, in some water. IV. Comp. tincture of gentian. . .fl.oz. 1 Tincture of columbo fl.dr. 4 Tincture of nux vomica fl.dr. l / 2 Nitromuriatic acid fl.dr. 2 Simple syrup, to make fl.oz. 4 The dose is a teaspoonful 3 times daily. V. Many kinds of dyspepsia tablets have appeared on the market. Some- thing very similar may be prepared ac- cording to this formula: Sodium bicarbonate gr. 5 Resin of jalap gr. 1 Ext. of hydrastis, powder gr. 3 Menthol gr. % Make 1 tablet. Pepsin may be added if desired, but it will not serve any pur- pose whatever in the mixture. One, two or three of the tablets may be taken after each meal. This mixture may conveniently be compressed by or.e of the hand compres- sors now so readily obtained. VI. Pepsin (1:3000) gr. T / 2 Bismuth subnitrate gr. 1 Magnesium carbonate gr. 2 Jamaica ginger gr. Vs Sugar, to make gr. 10 Take one or two after each meal. Ear Medicines. Medicines for the ear are of two kinds, one for earache, which may be called Earache Drops, Earache Reme- dies, or Earache Oils, the other being in- tended for the improvement of the hear- ing, the latter kind being known as Ear Oils or Acoustic Oils. Of course no medicine will actually improve the hear- ing when impaired, unless it be due to a waxy concretion present, which may be softened and dissolved. Earache Remedies. I. Olive oil fl.dr. 4 Chloroform fl.dr. 4 II. A mixture of equal parts of lauda- num and sweet oil is an old favorite. Acoustic Oils. III. Oil of turpentine fl.dr. 1 Oil of sweet almonds fl.dr. 6 One to 2 drops on cotton in the ear. IV. Olive oil fl.oz. 2 Oil of cajeput m. 15 Oil of sassafras m. 30 Acetic ether m. 10 Camphor , , gr. 60 Mix and dissolve, DOMESTIC PREPARATIONS. 573 Eczema or Salt Rheum, Remedies for. Eczema is a very common skin disease which manifests itself in a great variety of forms, all of which require different treatment. The formulas given below are used. Sometimes a lotion or pow- der acts best, at other times an oint- ment is to be preferred. The disease is believed not to be of a parasitic character. I. Rice flour dr. 4 Talcum dr. 2 Zinc oleate dr. 1 Bismuth subnitrate dr. 1 This should be dusted freely on the surface, and repeated every 2 or 3 hours. Sometimes, on account of the intense pruritis or itching, it is necessary to ap- ply a cooling application; a solution of thymol, 1 to 1,000, is very good. Sali- cylic acid and menthol are also useful. II. Menthol gr. 1 Salicylic acid dr. 1 Tincture of benzoin fl.dr. 3 Cologne water fl.dr. 6 Gly cerin fl.dr. 6 Alcohol fl.oz. 3 Water fl.oz. 3 Dissolve the menthol and acid in the alcohol, add the tincture and cologne and then the other ingredients, and shake well. After applying this, the above powder (No. 1) should be dusted on freely. Continue the cooling treatment with thy- mol as long as the active stage continues, and then use a mild ointment containing substances that influence the inflamma- tion, such as the next formula. III. Carbolic acid drops 15 Ichthyol gr. 50 Bismuth subnitrate • gr. 75 Zinc oxid av.oz. y 2 Cold cream av.oz. 1 Petrolatum av.oz. 1 Apply twice a day. This is to be used in the mild stage. IV. This is recommended by Unna. Zinc oxid ...,.,,.,,,,,,.,, av.oz. 4 Chalk, precipitated av.oz. 2 Lead water fl.oz. 2 Linseed oil, raw fl.oz. 2 Mix the chalk and zinc oxid; emulsify the lead water and linseed oil by shak- ing together. Finally mix the powders with the emulsion, rubbing constantly until a smooth paste is obtained. V. Lassar's Paste is also used. See formula in Part I. Epilepsy Remedy. "Brown-Sequard's Anti-Epileptic Mix- ture" is a preparation still in extended use, but various formulas for it have appeared. The following may be em- ployed : I. Sodium bromid gr. 180 Potassium bromid gr. 180 Ammonium bromid gr. 180 Potassium iodid gr. 90 Ammonium iodid gr. 90 Ammonium carbonate gr. 60 Tincture of columbo fl.oz. 1^2 Water, to make fl.oz. 8 Mix, dissolve, and filter. II. Potassium iodid gr. 60 Potassium bromid gr. 60 Ammonium bromid gr. 30 Potassium bicarbonate gr. 40 Infusion of columbo fl.oz. 6 Mix, dissolve and filter. The dose is a teaspoonful before each meal and three dessertspoonfuls on go- ing to bed. If the pulse is feeble, the potassium bicarbonate is replaced by am- monium carbonate and the infusion by i l / 2 fluidounces of tincture of columbo and 4 l / 2 fluidounces of water. Eye Medicines. The public demand for preparations for the eye is not large, but it is quite steady, and the formulas here given will suffice for the ordinary affections. If the condition of the eye seems at all serious or is long continued, the patient should invariably be advised to consult a physician who makes a specialty of ophthalmology. - The remedies for the eye maybe either lotions or ointments. Suitable names are 574 THE STANDARD FORMULARY Eye Medicines (Cont'd). the following: Reliable Eye Salve (or Water), White Eye Salve (or Water), Standard Eye Salve (or Water), Impe- rial Eye Salve (or Water), White Rose Eye Water, etc. Waters. I. Boric acid gr. 80 Zinc sulfate gr. 8 Glycerin fl.oz. 1 Rose water fl.oz. 7 Mix, dissolve and filter. II. This is known as Mackenzie's Eye Lotion. Mercuric chlorid gr. 2 Ammonium chlorid gr. 12 Cochineal gr. 3 Alcohol fl.dr. 2 Water, to make fl.oz. 16 Mix and filter after 12 hours. Salves. All ointments for the eyes must be re- duced to a thoroughly smooth condition. III. Zinc oxid gr. 5 Morphine sulfate gr. 2 Camphor gr. 1 White wax dr. 2 Lard, fresh dr. 6 Oil of rose, enough to perfume. Melt the wax, add the lard, allow to cool, when nearly cold add the camphor, allow it to dissolve, and then incorporate with the other ingredients so as to make a smooth ointment. IV. Morphine sulfate gr. 5 Yellow mercuric oxid gr. 15 Zinc oxid gr. 60 White petrolatum av.oz. 2 Mix well. Feet, Preparations for the. The preparations here mentioned are used for tenderness or soreness of the feet, also for excessive perspiration and fetor. These affections are tolerably common, but do not appear to the pub- lic to be of sufficient importance to make it necessary to consult a physician. Most remedies recommended by phar- macists are in powder, by reason of the majority of them containing talcum with salicylic acid. These powders should al- they will prove irritating to the already sensitive integument. They should be sprinkled into the socks and shoes in the morning. I. Salicylic acid gr. 105 Boric acid, fine powder gr. 350 Talcum, fine oowder av.oz. 7 This is the Salicylated Powder of Tal- cum of the N. F. The corresponding preparation of the German Pharmaco- poeia contains starch instead of boric acid. II. Mercuric chlorid gr. 1 Sodium salicylate av.oz. 1 Prepared chalk av.oz. 1 Dust a little of the powder in the socks every morning. III. Salicylic acid av.oz. *4 Alum, powder av.oz. Vz Starch av.oz. 2 Talcum, powder av.oz. 7 Oil of bergamot fl.dr. 1 Alcohol fl.dr. 4 Dissolve the acid and oil in the alco- hol, and rub in mortar with the other ingredients until the alcohol is dissi- pated. IV. Orris, powder . .av.oz. 1 Zinc oxid av.oz. 3 Talcum powder av.oz. 6 V. Potassium permanganate gr. 8 Thymol gr. 16 Distilled water fl.oz. 16 Mix and dissolve. This is to be used as a wash once daily for excessive perspiration and fetor of the feet. Female Disorders, Remedies for. Remedies for female disorders are of several kinds. Many are uterine tonics (such as Nos. I and III below), these being intended to strengthen or "tone up" organs of gestation to fit woman to endure child bearing with comfort, to prevent, relieve and cure distressing DOMESTIC PREPARATIONS. 575 pains which occur from excessive or tardy menstruation, and to relieve the nervous disorders accompanying these complaints. These preparations are known by such names as Woman's Friend, Female Remedy, Female Tonic, etc. I. Fluid ext. of squaw vine fl.oz. 4 Fluid ext. of cramp bark. . .fl.oz. 2 Fluid ext. of blue cohosh. fl.oz. 2 Fluid extract of damiana. . .fl.oz. 2 Fluid extract of helonias. . .fl.oz. 2 Fluid extract of cinchona. . .fl.oz. 2 Sherry wine fl.oz. 50 The dose is a tablespoonful 3 times a day. II. Fluid ext. of castor oil plant leaves fl.oz. 12 Fennel seed av.oz. 4 Anise seed av.oz. 4 Wintergreen herb av.oz. 4 Simple elixir, to make fl.oz. 48 Mix the three drugs, reduce to coarse powder, and extract by slow percolation, using the elixir as a menstruum. When 36 fluidounces of percolate are obtained, add to it the fluid extract. The dose is a teaspoonful every 3 hours. III. The following are excellent "pe- riodical pills," so-called, for retarded menstruation : Ergotin .- gr. 1 Aloes gr. 1 Extract of cotton root gr. 1 Ferrous sulfate, dried gr. 1 Oil of savin m. y 2 Or the emmenagogue pills mentioned in Part I under Pills may be used. IV. The following makes an excel- lent uterine astringent tablet useful for leucorrhea : Extract of henbane gr. 1 Extract of witch hazel gr. 1 Extract of helonias gr. 1/2 Extract of opium gr. 1/4 Boric acid gr. 5 Tannic acid gr. 1 Salicylic acid gr. 1 Alum gr. 1 Eucalyptol gr. 1/16 Thymol gr. 1/32 Use 2 to 4 tablets in a quart of luke- warm water as a vaginal douche twice daily. Gargles. See formula under Throat Affections, Remedies for. Gonorrhea and Gleet, Remedies for. Remedies for gonorrhea may be used externally (so-called) or may be exhib- ited internally. The external remedies are usually in the form of "injections," or "washes," as they are also termed. These usually contain a zinc sulfate or acetate combined with hydrastis or one of its alkaloids, lead acetate, opium, car- bolic acid, or other substance. The rem- edies for internal use contain copaiba or santal oil or both combined with cubeb, matico, spirit of nitrous ether, gum tur- pentine, eucalyptus, etc. These internal medicines may take the form of paste, capsules, pills or emulsions. The "ex- ternal" and "internal" remedies may be used simultaneously, although there is no benefit to be gained by their conjoint use. The "external" remedies usually are known by some fanciful or odd title, or by a number such as "55," "400," etc. The "internal" remedies are usually known by such titles as Sandalwood Pills, Paste of Copaiba, Cubeb and San- tal, Paste of Copaiba and Santal, Paste of Copaiba, Cubeb and Matico, Gonor- rhea Paste, Confection of Cubeb and Copaiba, Mass of Copaiba, etc. Remedies for external use may also be in the form of bougies; one example of these is given among the following for- mulas. Every patient suffering with gonorrhea should be advised to keep the bowels well open and also to refrain from the use of any stimulants during the course of the disease. Gleet is simply a chronic form of gon- orrhea. I. Potassium citrate av.oz. 1 Syrup of citric acid fl.oz. 2 Water, to make fl.oz. 8 5T6 THE' STANDARD FORMULARY Gonorrhea Kemediec (Cont'd). This is to be taken only in the very first stages of the disease to render the urine alkaline. A tablespoonful is to be taken 3 times daily. If given early enough, it will effect a cure without fur- ther treatment. Injections. II. Berberine hydrochlorid gr. 15 Zinc acetate gr. 15 Glycerin fl.dr. 4 Water, to make fl.oz. 8 This is to be used as a urethral injec- tion several times daily. III. Tincture of hydrastis fl.dr. 4 Lime water, to make fl.oz. 8 To be used like No. I. IV. Zinc sulfate gr. 10 Lead acetate gr. 10 Comp. tincture of catechu. . .fl.dr. 1 Tincture of opium fl.dr. 3 Water, to make fl.oz. 8 To be used like No. I. V. This has been called Bumsted's Gleet Cure. Zinc sulfate gr. 15 Extract of opium gr. 8 Glycerite of hydrastis fl.dr. 2 Glycerin fl.oz. 1 Water, to make fl.oz.- 8 To be used like No. I. VI. The newer silver salts such as protargol and nargol are regarded with favor by physicians in the treatment of gonorrhea. Aqueous solutions contain- ing 54 to 1 per cent may be used for acute cases, while chronic cases may be treated with solutions containing 1 to 5 per cent. These compounds are easiest dissolved by triturating them in a mor- tar with a small amount of glycerin to a smooth paste, then adding the water. These injections are to be used sev- eral times daily. Pastes. VII. Balsam of copaiba fl.oz. 2 Glycerin fl.dr. 3 Sugar, powder av.oz. 2 Calcined magnesia av.oz. 2 Licorice root, powder av.oz. i l / 2 Rub up the copaiba and glycerin inti- mately together, and then add the re- maining ingredients gradually in the or- der named. VIII. Balsam of copaiba av.oz. 4 Oil of sandalwood fl.oz. 1 Gum turpentine av.oz. 4 Cubeb, powder sufficient Melt the turpentine with the copaiba by the aid of gentle heat, add the oil and incorporate in the melted mass as much of the cubebs as will form a suitable paste. Dose, size of a pea 3 or 4 times a day. Pills or Capsules. IX. Oil of sandalwood gr. 300 Yellow wax gr. 300 Melt the wax at the lowest possible temperature, add the oil, allow to cool, and divide into 100 pills or capsules. One pill is to be taken every 3 hours. Bougies. X. Carbolic acid drop 1 Iron persulfate, powder gr. 4 Zinc acetate gr. 10 Extract of hydrastis gr. 30 Extract of belladonna gr. 30 Cocoa butter, grated sufficient Convert this mixture into 30 bougies, each 2 inches long and about J4 i ncn thick. These may be rolled out on a pill tile or pill machine. See Suppositories, Part I, for details as to method of mak- ing them. These bougies maybe advised for gon- orrhea, gleet and spermatorrhea (noc- turnal emissions). One is to be inserted in the urethra at night. Emulsion. XI. Balsam of copaiba ....fl.oz. 2 Oil of sandalwood ....fl.dr. 4' Oil of wintergreen. . . . ....fl.dr. I Acacia, powder . . .av.oz. I Simple syrup ... .fl.oz. 4 Water, to make ....fl.oz. 16 Mix the balsam and two oils and trit- DOMESTIC PREPARATIONS. 577 urate this mixture intimately with the gum ; then add all at once 2 fluidounces of water, triturate rapidly until an emul- sion is formed, and add the remainder of the water and the syrup. The dose is a teaspoonful every 3 or 4 hours. Gout, Remedies for. See under Rheumatism and Gout. Hay Fever Remedies. I. Boric acid gr. 60 Sodium salicylate gr. 75 Cocaine hydrochlorid gr. 4 This powder is to be insufflated into the nostrils frequently during the day. For the eyes, where affected, a wash of zinc or copper sulfate should be used. II. Cocaine hydrochlorid gr. 6 Carbolic acid gr. 10 Menthol gr. 20 Sweet almond oil fl.dr. 2 Ointment of zinc oxid gr. 240 This is to be applied on a cotton pledget. • The cocaine makes the above two formulas dangerous without specific warning against the continued use of the preparations. Beta-eucaine may be sub- stiuted for the cocaine. Topical applications like the above should be used in connection with tonics internally, such as elixir of iron, quinine and strychnine ; a preparation containing arsenic is also excellent. Headache Remedies. Headache remedies are now quite nu- merous and almost every pharmacist prepares a remedy to replace the "pat- ented" articles. These remedies are us- ually put up in the form of powders, capsules, wafers, pills and tablets, but the ingredients are practically alike. The common ingredients of these prepara- tions are acetanilid, phenacetin, caffeine, bromids, sodium bicarbonate (to correct acidity of the stomach), etc. Some of the headache remedies appear in the form of effervescent salts ; the in- gredients are, however, similar to those of the other remedies. Headache powders (or pills, capsules or tablets) are usually directed to be taken 15 or 20 minutes apart, but owing to the presence of acetanilid in most of them it is not safe to take more than two doses. If two fail to cure the head- ache, some external application should be tried. The dose of the effervescent salts is a heaping teaspoonful in a third of a tumblerful of water. I. Acetanilid gr. 7 Sodium bicarbonate gr. 2 Caffeine gr. 1 Make one powder, pill, capsule or tab- let. II. Phenacetin gr. 10 Caffeine . .' gr. 1 Make one powder, pill, capsule or tab- let. III. Acetanilid av.oz. 1 Sodium salicylate dr. 2 Cerium oxalate dr. 1 Mix, make 10 gr. doses, and form into powders, pills, capsules, etc. IV. Dr. C. L. Kerr's formula: Acetanilid gr. 3 Ammonium chlorid gr. 1 Citrated caffeine gr. y 2 Sodium bicarbonate gr. y 2 Make one powder, pill, capsule or tab- let. V. Two excellent formulas from the U. S. P. and the old N. F. are in Part I under the name Compound Acetanilid Powder (see Powders). VI. Effervescent Potassium Bromid with Caffeine, Part I, will also be found serviceable. VII. Caffeine gr. 80 Ammonium carbonate gr. 80 Elixir of guarana, to make.fl.oz. 4 Mix and dissolve. The dose is a teaspoonful every hour until relieved. This is suitable for neu- ralgic headaches. 578 THE STANDARD FORMULARY Headache Remedies (Cont'd). VIII. This is used in the Philadel- phia Hospital. Acetanilid gr. 80 Alcohol .. .fl.oz. 1 Aromatic spirit of ammonia. fl.oz. 1 Compound tincture of car- damom fl.oz. 1 Simple elixir, to make fl.oz. 4 Dissolve the acetanilid in the alcohol and add the other ingredients. The dose is a teaspoonful. IX. Oil of lavender flowers fl.dr. 1 Camphor av.oz. 1 Ammonia water fl.oz. 4 Alcohol, to make fl.oz. 16 Dissolve the camphor and oil in the alcohol and then add the water. This is for inhalation and application to the forehead. Hives, Remedies for. Hives, called urticaria in medical par- lance, is an affection most common in summer time and is more common in children than in adults. It appears as large, reddened, elevated patches on the skin and itches intensely. It is caused by some gastro-intestinal derangement. Some persons cannot eat certain articles of food without getting an attack of hives. The best internal treatment is full doses of sodium phosphate given sev- eral times daily to keep the bowels open. Externally apply some cooling lotion to relieve itching, such as a weak carbolic acid solution (1 dr. to 1 pint of water), an alkaline solution like sodium bicar- bonate in water, menthol (5 or 10 grains to the ounce of solution or ointment), or vinegar or acetic acid (to contain about 4 or 5 per cent of acetic acid). Or use the following: Sodium borate av.oz. y 2 Carbolic acid fl.dr. 1 Glycerin fl.dr. 2 Alcohol fl.oz. 2 Water, to make fl.oz. 16 This is to be applied frequently to the skin. Insect Stings, Application for. See Stings and Bites, Treatment for. Itch, Remedies for. The disease known as itch, or, more properly, scabies, is a very annoying and tolerably common complaint. It is a parasitic skin disease, caused by a min- ute insect called itch-mite or acarus, which burrows under the skin. The mode of treatment is practically the same as for the other skin diseases. The remedies mentioned below are all to be applied several times daily. I. Compound Sulfur Ointment (see formula in Part I under Ointments), also known as Wilkinson's Ointment or Hebra's Itch Ointment, is an excellent remedy for the itch. II. Red oxid of mercury dr. 2 Burgundy pitch dr. 2 Oil of turpentine fl.dr. 2 Lard av.oz. 4 Suet av.oz. 4 Melt the pitch, add the suet and lard, mix well, allow to cool, add the oil, and then incorporate thoroughly with the mercury oxid. III. Menthol gr. 100 Peru balsam gr. 200 Lanolin av.oz. 9 Dissolve the menthol in the lanolin melted at a very gentle heat and incor- porate the balsam with this solution. Kidney Remedies. Some years ago preparations for the kidneys were marketed under the name of Buchus; there have also been Diure- tic Elixirs, and now these preparations are usually termed Kidney and Liver Remedies. The latter are therefore to be recommended for affections of the liver, kidney and urinary organs. Many of the remedies for liver complaints may consequently be recommended for kidney affections and conversely many remedies for the kidney may be recom- mended for the liver. Kidney remedies need not necessarily be of the liquid form ; they may be in the form of coarse powder or species which should be infused with water be- DOMESTIC PREPARATIONS. 579 fore using. Kidney remedies in pill form are now popular. Liquids. The dose of these preparations is a tablespoon ful 3 times a day. I. Formula of the Illinois Pharma- ceutical Association: Liverwort av.oz. 4 Hydrangea av.oz. 4 Broom tops av.oz. 4 Canadian hemp (apocyn- um) av.oz. 4 Couch grass av.oz. 4 Potassium nitrate av.oz. 3 Alcohol fl.oz. 12 Syrupy glucose fl.oz. 12 Water, to make fl.oz. 64 Infuse the drugs with hot water so as to make 40 fluidounces of product, and to this add the alcohol and glucose. Fluid extracts may be substituted for the drugs, in which case the alcohol should be omitted. II. Liverwort av.oz. 2 Couch grass av.oz. 2 Wintergreen av.oz. 1 Jamaica dogwood av.oz. H Potassium nitrate av.oz. y 2 Alcohol fl-oz. 16 Glycerin fl.oz. 6 Water, diluted alcohol, to make .fl.oz. 64 Grind the drugs to coarse powder, per- colate with all the glycerin and alcohol mixed with 16 fluidounces of water. When that has all passed add enough di- luted alcohol to make 64 fluidounces and in this dissolve the potassium nitrate. Teas. A teaspoonful is to be steeped for a few minutes in hot water and drank 3 times a day. III. Buchu av.oz. 8 Uva ursi av.oz. 8 Juniper berries av.oz. 4 Make into coarse powder. IV. Chicory av.oz. 9 Couch grass av.oz. 2 Senna , av.oz. 2 Bittersweet av.oz. 2 Red clover av.oz. 1 37 All the drugs should be cut tolerably fine and be well mixed. Pills. V. Extract of asparagus gr. 1/5 Extract of buchu gr. 1/6 Extract of uva ursi gr. 1/6 Extract of pareira brava gr. 1/16 Oil of juniper m. 1/6 Oleoresin of cubeb m. 1/12 The dose is one or two pills 3 times daily. Lice, Application for. Pharmacists are frequently called upon to recommend something for lousiness (pediculosis is the medical term). Head lice are most frequent in children, body and crab lice in adults, but the method of treatment is the same. Mercurial ointment is a favorite application, but is objectionable on account of its greasi- ness. Insect powder, powdered sabadilla seed, powdered sulfur, sulfur ointment, and solution of carbolic acid are also used. To remove the "nits," dilute acetic acid, dilute alcohol, or mild alkaline so- lutions should be frequently used. These may be combined with parasiticides as in the following: I. Fluid ext. of stavesacre fl.oz. 1 Diluted acetic acid fl.oz. 15 Mix and filter. II. Stavesacre seed, powder. . .av.oz. 4 Oil of lemon drops 20 Oil of lavender flowers. .. .drops 10 Oil of rose geranium drops 10 Tincture of cudbear fl.dr. 4 Acetic acid fl.oz. 2 Water, to make fl.oz. 32 Alcohol fl.oz. 8 Mix the powder, acid and 24 fluid- ounces of water, boil p-ently for 10 min- utes, and allow to cool. Dissolve the oils and tincture in the alcohol, add this to the decoction, stir well, let stand a few hours, strain with expression, add enough water through the strainer to make 32 fluidounces of liquid and finally filter. These preparations are to be applied twice daily. ISO THE STANDARD FORMULARY Liniments. Liniments are in considerable demand and every pharmacists should have such a preparation ready to offer for sale. Some of these liniments may also be taken internally for cramps, cholera, di- arrhea, etc., and these may be known by such titles as Pain Cure, Pain Dispeller, Pain Relief, Rapid Relief, etc. Other names which may be employed are Stim- ulant Liniment, Electric Liniment, Kero- sene Liniment, Embrocation, Nerve and Bone Liniment, Arnica Liniment, Rheu- matic Oil, Rheumatic Liniment, Univer- sal Liniment, Rocky Mountain Liniment, Family Liniment, Magic Liniment, Home Liniment, Penetrating Liniment, Red Oil, Indian Liniment, Wizard Liniment, Wiz- ard Balm, Golden Oil, Knickerbocker Liniment, Bicycle Liniment, etc. If it be white, it might be known as White Lini- ment or Cream Liniment. The word "oil" is rather more popular as a name for an external application than the word "liniment." These liniments are recommended for rheumatism, neuralgia, bruises, chil- blains, frost bites, sprains, stings and bites of insects, lameness, etc. Many of the preparations may also be employed for veterinary purposes. Kerosene Liniment. I. Capsicum, powder gr. 60 Fusel oil fl.dr. 4 Oil of origanum fl.dr. 4 Oil of sassafras fl.oz. 1 Oil of turpentine fl.oz. 8 Kerosene oil fl.oz. 38 Mix the whole, macerate for 24 hours and strain through muslin. II Castile soap, powder av. oz. 4 Oil of camphor fl.oz. 2 Tincture of arnica fl.oz. 16 Distilled extract of witch- hazel fl.oz. 16 Alcohol fl.oz. 24 Water fl.oz. 8 Mix the soap, alcohol and oil, shake well, add the other ingredients, let stand for several days, shaking occasionally, and filter. Witchhazel Liniment. Ill Camphor av.oz. 2 Ammonia water fl.oz. 5 Tincture of capsicum fl.oz. 5 Distilled extract of witch- hazel fl.oz. 10 Alcohol fl.oz. 34 Color with caramel. Dissolve the camphor in the alcohol and add the other ingredients. Spirit of ammonia in the above will make a better mixture than ammonia water. Lightning* Iodin Liniment or Lini- ment of Ammonium Iodid. IV Iodin gr. 280 Oil of rosemary fl.dr. 10 Camphor gum av.oz. 4 Tincture of opium fl.oz. 5 Chloroform fl.oz. 6 Alcohol fl.oz. 40 Ammonia water, to make.. fl.oz. 64 Dissolve the iodin, oil and camphor in the alcohol and chloroform, and add the other ingredients. This should be put up in amber-pol- ored, rubber-stoppered vials. This is similar to Liniment of Am- monium Iodid in Part I, which see. The following has been called "Nerve and Bone Liniment." V. Oil of origanum fl.oz. 1 Oil of rosemary fl.oz. 1 Oil of amber fl.oz. 1 Oil of hemlock fl.oz. 1 Oil of turpentine fl.oz. 32 Linseed oil fl.oz. 16 Color with alkanet. Mustard Liniment. VI Oil of mustard fl.dr. 2 Oil of turpentine fl.dr. 2 Clhoroform fl.dr. 2 Alcohol, to make fl.oz. 16 Neuralgia Liniment. VII Menthol dr. 2 Gum Camphor dr. 2 Oil of sassafras fl.dr. 2 Ether fl.dr. 4 Chloroform fl.dr. 4 Alcohol, to make fl.oz. 8 DOMESTIC PREPARATIONS. 581 Apply to parts affected and cover for a few minutes with a woolen cloth. Liniment Containing Egg, VIII Castile soap, powder av.oz. 2 .fl.oz. .fl.oz. .fl.oz. fl.oz. 8 Oil of origanum Oil of turpentine Camphorated oil Ammonia water Yolks of 4 eggs. Mix well. This is a formula for the preparation known as White Oils. IX. Acetic Turpentine Liniment, also called Stokes' or St. John Long's Lini- ment (see formula in Part I under Lini- ments) is another external application containing egg. Fluid Lightning. X. The following is similar to certain preparations known by the term Fluid Lightning : Aconitine gr. 2 Oil of mustard fl.dr. 2 Chloroform fl.dr. 2 Ether, stronger fi7oz. 1 Alcohol, to make fl.oz. 12 The above- is a valuable external ap- plication for headache, rheumatism, neuralgia, and all nervous pains. Miscellaneous Liniments. XI. Oil of camphor. . . . Oil of turpentine.. Benzine, deodorized Cottonseed oil .... Capsicum, powder.. Macerate the capsicum with the ben- zine for 3 days, agitating frequently, and strain. Mix the oils of camphor, turpentine and cottonseed and add the previous liquid. XII. Tincture of cantharides. Tincture of myrrh Tincture of guaiac Oil of hemlock Oil of turpentine Oil of camphor Cottonseed oil Water of ammonia, strong. .fl.oz. 4 Solution of potassa fl.oz. 1 -XIII. Any of the limiments mentioned in Part I may also be used. .fl.oz. 8 .fl.oz. 40 .fl.oz. 16 .fl.oz. 16 av.oz. 1 .fl.oz. 3 .fl.oz. 4 .fl.oz. 1 .fl.oz. 2 .fl.oz. 8 .fl.oz. 16 .fl.oz. 32 Pain Relief. (For internal and external use.) The preparations under this heading may be used externally like the preced- ing liniments and also internally as quick stimulants and pain relievers in cases of cholera, colic, cramps, colds, etc. The dose is one-half to one teaspoonful in some hot water every hour or so. At the same time the preparation may be applied externally. XIV. Tincture of guaiac fl.oz. 2 Tincture of myrrh fl.oz. 2 Tincture of capsicum fl.oz. 4' Spirit of camphor fl.oz. 8 rucunui XV. 11. U£. 1U Oil of cinnamon fl.dr. 2 Oil of clove fl.dr. 4 Oil of turpentine fl.oz. 1/2 Oil of sassafras fl.dr. 2 Ammonia water fl.dr. 2 Chloroform fl.oz. 1 Alcohol, to make fl.oz. 32 Liver Medicines. Medicines for the liver are usually termed Liver Invigorators or Liver Regulators, very frequently Kidney and Liver Remedies ; in fact most medicines for liver complaints are. also recom- mended for derangements of the kid- neys. Some of the liver medicines as- sume the liquid form, some are in the form of species, some in pill form, etc. In addition to the formulas here men- tioned, some of the blood purifiers, "bit- ters," cathartics, and kidney remedies may be recommended for assisting the liver in its functions. Liquids. Fluid extract of rhubarb. . .fl.oz. 2 Fluid extract of leptandra. .fl.oz. 2 Fluid ext. of mandrake. .. .fl.oz. 2 Compound tincture of carda- mom fl.oz. 4 Comp. tincture of gentian. . .fl.oz. 8 Tincture of ginger fl.oz. 2 Simple elixir fl.oz. 12 The. dose is one or two teaspoonfuls 3 times a day. 582 THE STANDARD FORMULARY Liver Medicines (Cont'd). II. Fluid ext. of leptandra fl.oz. I Fluid ext. of mandrake fl.oz. I Fluid ext. of serpentaria. .. .fl.oz. 2 Fluid extract of senna fl.oz. 5 Diluted alcohol, to make fl.oz. z 2 This is to be used like the preceding. Teas. III. Leptandra av.oz. 2 Serpentaria av.oz. 2 Liverwort av.oz. 2 Senna av.oz. 2 Butternut av.oz. 2 Licorice root av.oz. 1 Anise av.oz. 1 Mix and reduce to coarse powder. The dose is a teaspoonful steeped in hot water and strained, taken 3 times daily. IV. Senna av.oz. 8 Serpentaria av.oz. 4 Star grass av.oz. 2 Golden seal av.oz. 1 Make into a coarse powder. Use like the preceding. Pills or Capsules. V. Resin of scammony gr. 20 Socotrine aloes gr. 20 Blue mass gr. 20 Oil of anise m. 5 Make into a mass and divide into 20 pills or capsules. The dose is one or two pills at night. The pills mentioned under Cathartics are also to be recommended as "liver pills." Moles, to Remove. Tartar emetic, fine powder dr. 1 Venice turpentine dr. 1 Soap plaster dr. 3 Mix intimately, and spread upon ad- hesive plaster. Apply firmly to the sur- face of the mole, and remove when sup- puration sets in. Nervous Debility, Remedies for. Of late it has become quite the fashion for the public in general to believe they are suffering from nervous disorders, and many so-called "nervines" have ap- peared upon the market. Some of these contain celery, others phosphorous and damiana, the latter also frequently con- taining kola, nux vomica, gentian, cin- chona, or columbo. These preparations may, according to their form or composition, be known as Celery Compound, Celery Nervine, Cel- ery Tonic, Celery and Kola, Celery, Cor- dial, Nerve Tonic, Vitalizer, Vitalizing Tonic, Damiana Compound, Nervous Debility Pills, Aphrodisiac Pills, Com pound Damiana Pills, etc. Liquids Containing Celery. Most of the preparations mentioned under this heading are excellent tonics; the celery is added merely in deference to popular notion. Only one contains kola, but a small amount, about 4 ounces to the gallon, may be added if desired; the preparation may then be known as "celery and kola" or "celery and kola nerve tonic." The dose of these preparations is one or two tea- spoonfuls after each meal. I. Celery seed av.oz. 8 Red cinchona av.oz. 4 Orange peel (sweet or bit- ter) av.oz. 1 Coriander seed av.oz. 1 Lemon peel av.oz. 1 Muriatic acid fl.dr. 1 Alcohol fl.oz. 20 Glycerin fl.oz. 16 Water fl.oz. 16 Simple syrup fl.oz. 16 Diluted alcohol, to make. . . .fl.oz. 64 Mix all the drugs and grind to a mod- erately coarse powder. Mix the acid, alcohol, glycerin and water ; percolate the drug with this mixture, adding enough diluted alcohol to make 48 fluid- ounces. Add the syrup and if necessary filter. II. Celery seed av.oz. 4 Coca leaves av.oz. 4 Black haw av.oz. 4 Mandrake av.oz. 2 Orange peel (sweet or bit- ter) av.oz. 1 Sugar av.oz. 16 Diluted alcohol, to make fl.oz. 24 Mix the drugs, reduce them to coarse DOMESTIC PREPARATIONS. 583 powder, and extract in the usual way by percolation with diluted alcohol to obtain 54 fluidounces of percolate; in this dissolve the sugar by agitation and strain. III. Compound Elixir of Celery is also an excellent preparation of this kind. See formula in Volume I under Elixirs. Liquids Containing Damiana. These are also tonics like the preced- ing, and the damiana is added also in deference to popular notion; its value is problematical. IV. Potassim hypophosphite ...av.oz. 1 Fluid ext. of nux vomica. . .fl.dr. 2 Fluid ext. of damiana fl.oz. 4 Fluid extract of coca fl.oz. 4 Diluted hydrobromic acid. . .fl.oz. 4 Water fl.oz. 4 Simple elixir, to make fl.oz. 64 Dissolve the hypophosphite in the wa- ter, add the other ingredients, and filter. The dose is one-half to one table- spoonful 3 times a day before meals. Damiana av.oz. 8 Gentian av.oz. 8 Columbo av.oz. 8 Nux vomica av.oz. 3 Phosphoric acid fl.oz. 2 Alcohol, water, each sufficient Mix the drugs in ground form, per- colate with a mixture of 1 volume of alcohol and 3 of water so as to obtain 62 fluid ounces of percolate and to this add the acid. The dose is one or two teaspoonfuls after each meal. Neuralgia Remedies. Neuralgia may be treated externally or internally or both. Very often one of the headache remedies will afford relief (see formulas under Headache Remedies). Or a neuralgia pill may be used (see formulas for Gross's and Brown-Sequard's pills under Pills in Part I). Very frequently an external application will afford relief such as Neuralgia Liniment mentioned under Liniments in this part or the ointment (No. Ill) mentioned under Rheuma- tism and Gout Remedies, or Liniment of Aconite and Chloroform in Part I. under Liniments. The preparations men- tioned under Rheumatism and Gow Remedies will often give relief in neu- ralgia. Other preparations to use are the following: I. Menthol gr. 45 Cocaine, muriate gr. 15 Chloral, hydrate gr. 10 Petrolatum gr. 300 Apply to painful part, covering with muslin afterwards. II. Oil of peppermint fl.oz. 1 Chloroform fl.oz. 2 Tincture of aconite fl.oz. 4 Apply every half hour or every hour. III. When the neuralgia is due to rheu- matism or gout, the following is useful : Antripyrin dr. 2 Sodium salicylate dr. 4 Aromatic spirit of ammonia. fl.oz. 1 Simple elixir, to make fl.oz. 6 The dose is a dessertspoonful every 2 to 4' hours. Nipples, for Fissured. — (Mammillary Lotions, Ointments, etc.) These preparations are to be applied after each nursing, and the nipples are to be cleansed carefully before the next nursing. I. Ichtyol gr. 120 Lanolin gr. 180 Glycerin fl.dr. 3 Olive oil fl.dr. 1 II. Salicylic acid gr. 30 Tannic acid gr. 8 Borax dr. 1 White wax dr. 2 Lard, benzoinated dr. 6 III. Salol gr. 60 Cocaine hydrochlorid gr. 2 Ether fl.dr. 1 Collodion fl.dr. 7 This is to v be painted on with a cam- el's hair pencil. IV. To prevent Assuring of the nipples, 584 THE STANDARD FORMULARY Mamillary Lotions (Cont'd). apply lanolin with the onset of labor four times daily till lactation is estab- lished. The nipples are then, after each nursing, to be anointed with the fol- lowing : Compound tincture of ben- zoin drops 15 Olive oil fl.dr. 2 Lanolin dr. 6 Pile Remedies. Piles, or hemorrhoids, as they are more correctly termed, are a very com- mon and very annoying affection. They are termed "internal" piles when they exist within the sphincter controlling the muscles of the anus, and "external" piles when existing outside of this sphincter. Other terms also are used in describing them: Blind piles which are simply a varicose state of the veins without bleeding; itching piles, which are accompanied by itching; bleeding piles, which are accompanied by loss of blood at every evacuation ; and mucous piles, when pus or mucus only is dis- charged. Treatment of piles should be both constitutional and locd. The constitu- tional treatment should consist of the taking of compound licorice powder or one of the "bitter waters" at night. For local treatment, a mixture of an astrin- gent like nutgall, tannin, extract of witchhazel, extract of rhatany, lead ace- tate or iron subsulfate, with an anodyne like opium, belladonna, conium, tobacco, stramonium, ergot, or morphine is con- sidered advisable. Other agents some- times added to this mixture are anti- septics like iodoform, tar, peru balsam, carbolic acid, betanaphthol or salol. This mixture may assume the form of an ointment or of suppositories. The for- mer should be preferred for external, the latter for internal, piles. When the piles are only tolerably severe, these remedies afford prompt relief, but when quite severe, only surgical intervention will effect a cure. Ointments. These ointments are to be applied about twice daily. In cases of itching or external piles, they are to be ap- plied with the finger, but in bleeding and ulcerated piles the remedy should be pushed up into the rectum. This may also be done by means of the finger but the best way is by the use of a pile pipe. I. Ointment of Gall and Opium in Part I (see formula under Ointments) is an excellent ointment for piles. II. Fluid extract of witch- hazel fl.oz. 1 Peru balsam gr. 120 Fenugreek av.oz. 1 Petrolatum av.oz. 16 Paraffin av.oz. 4 Melt the petrolatum with gentle heat and macerate therein the fenugreek, for half an hour; then add the paraffin and strain through cloth. When about to solidify, add the extract of witchhazel to which the balsam has been added, stir until cool. III. Morphine sulfate gr. 8 Olive oil fl.oz. 1 Ointment of zinc oxid av.oz. 4 Nutgall, fine powder av.oz. 1 Suppositories. These are to be preferred for inter- nal piles. One should be inserted each night and in the morning also if possi- ble. IV. Extract of witchhazel gr. 60 Tannia gr. 12 Opium powder gr. 4 Cocoa butter gr. 180 Make into 12 suppositories. V. Iodoform gr. 30 Extract of belladonna gr. 3 Morphine sulfate gr. \ l / 2 Cocoa butter gr. 180 Make into 12 suppositories. Prickly Heat, Remedies for. "Prickly heat" is of course an affec- tion of the summer season. Treatment DOMESTIC PREPARATIONS. 585 should consist in removing unnecessary clothing, keeping in a cocl place and avoiding violent exercise. Food should be easily digestible and non-stimulating. Drinks should also be unstimulating — alcoholic drinks should sedulously be avoided — and should be cool but not ice- cold as the latter excites perspiration. If there is constipation a saline laxa- tive like rochelle or epsom salt or solu- tion of magnesium citrate should be giv- en. Local applications may consist of borated talcum, salicylated powder of talcum (see formula under Feet, Prep- arations for the), aqueous solution of sodium bicarbonate, borax or boric acid, or a solution of copper sulfate (10 grains to the ounce), preferably with a little carbonic acid will be found highly efficacious. The following has also been recommended : Carbolic acid m. 30 to 60 Boric acid dr. 4 Glycerin fl.dr. 1 Alcohol fl.oz. 2 Water fl.oz. 12 Rheumatism and Gout. Rheumatism may consist of remedies for internal or for external use. Those for internal use are to be preferred as affording better results, but the effects are still more marked if accompanied by the use of a suitable application (lini- ment). Rheumatism remedies are usually also recommended for gout. The rem- edies for the external treatment of gout may consist of liniments or ointments; an example of a suitable gout ointment is mentioned below. See also Liniments for suitable external applications. Internal Remedies. I Sodium salicylate av.oz. 3 Potassium acetate av.oz. 2 Fluid extract of colchicum seed fl.dr. 6 Fluid extract of black co- hosh fl.oz. 2 Oil of wintergreen m. 20 Alcohol fl.dr. 2 Simple syrup fl.oz. 4 Water, to make fl.oz. 24 Dissolve the oil in the alcohol, add the fluid extracts, then the other in- gredients, and dissolve by agitation. The dose is a teaspoonful every 3 hours. II Sodium salicylate av.oz. 2 Potassium iodid av.oz. 2 Potassium acetate av.oz. 2 Fluid ext. cascara sa- grada fl.oz. 4 Glvcerin fl.oz. 4 Peppermint water, to make. fl.oz. 24 The dose is a teaspoonful every 3 hours. External Application. III. Menthol gr. 80 Salicylic acid dr. 2 Camphor-chloral dr. 4 Capsicum powder dr. 4 Oil of mustard drops 30 Wool fat, hydrous.. av.oz. 2 Petrolatum, to make av.oz. 4 This is to be applied with vigorous friction 3 times a day. IV. Many of the liniments may be employed externally for the relief of rheumatic pains; some of the "blood purifiers" and possibly some of the "bit- ters" may be recommended for the cure of rheumatism. Ringworm Applications. This is a skin disease caused by in- fection with a vegetable parasite. This attacks the epidermis, the hair and hair follicle. Its characteristic feature is the circular patches which gradually increase in size. Any parasiticide remedies will cure the disease. These preparations should be rubbed in well several times a day. I. Iodin dr. 2 Potassium iodid dr. I Alcohol fl.dr. 6 Water, to make fl.oz. 2 II. Precipitated sulphur dr. 1 Ammoniated mercury dr. I Salicylic acid gr. 40 Wool fat, hydrous av.oz. 1 Petrolatum av.oz. I >Sfi THE STANDARD FORMULARY Ringworm (Cont'd). III. Unn's compound chrysarobin oint- ment: Chrysarobin gr. 160 Ichthyol gr. ioo Salicylic acid er. 60 Petrolatum av.oz. 2 Salves or Ointments. The ointments mentioned below are useful applications for cuts, burns, ul- cers, bruises, bites and stings of in- sects, frost bites, chilblains, bed sores, etc. Appropriate titles for these prepar- ations are Household Salve, Healing Salve (or Ointment), Carbolic Salve, Family Salve, Carbolized Ointment, Witchhazel Salve, etc. Other ointments useful for skin dis- eases may be found under the head of Remedies for Barber's Itch, Itch Rem- edies, Eczema Remedies, and Ringworm Applications. Carbolic Salves. I. Carbolic acid, crystal oz. V2 White wax av.oz. 2 Petrolatum av.oz. 16 Melt the wax and petrolatum; re- move from the fire and while cooling stir in the acid. II. Petrolatum av.oz. 16 Yellow wax av.oz. 1 x / 2 Camphor av.oz. 1 Carbolic acid, crystal oz. Vt. Oil of sassafras drops 30 Melt the carbolic acid and while warm add the camphor and oil of sassa- fras. Melt the wax and add to it the petrolatum, melting them together; while cooling but still liquid add the solution of camphor in carbolic acid and oil and stir occasionally while cooling. The caustic properties of the carbolic acid are neutralized in this preparation by the camphor. Arnica Salve. III. Solid extract of arnica dr. 2 Lard av.oz. 14^2 Yellow wax av.oz. i l / 2 Hot water sufficient Dissolve the extract of arnica in the hot water, and thoroughly incorporate it with the lard and beeswax previously melted together. Witchhazel Salve. IV. Fluid ext. witchhazel fl.oz. 2 Wool-fat av.oz 4 Petrolatum av.oz 16 Triturate the fluid extract with the wool-fat until well mixed, then incor- porate with the petrolatum. Healing or Family Salves. V. Tannin dr. 2 Oil of sassafras fl.dr. 2 Venice turpentine av.oz. 2 Zinc oxid av.oz. 4 Yellow wax av.oz. 4 Resin av.oz. 4 Lard av.oz. 16 Melt the wax and resin, add the lard and turpentine, and while cooling, in- corporate the other ingredients, taking care to make a perfectly smooth mix- ture. VI. Camphor gum av.oz. 1 Zinc oxid av.oz. 8 Paraffin wax av.oz. 4 Petrolatum av.oz. 40 Melt the paraffin, add the petrolatum, and, in this mixture, while still warm, dissolve the camphor; then thoroughly incorporate the zinc oxid. Stick Salve. VII. The so-called "stick salves" are solid preparations in the form of round sticks which soften upon the application of heat. They are recommended for burns, scalds, chilblains, frost-bites, boils, wounds, corns, ulcers, all kinds of sores and many other complaints. In using the salve cut into thin pieces and spread upon cloth or leather with a warm knife; or the end of the stick may be softened by warming over a lighted gas jet or a warm stove and then spread upon cloth or leather. Most of these "sticks" contain burgundy pitch, like the following : Burgundy pitch av.oz. 6 DOMESTIC PREPARATIONS. 587 Resin av.oz. 4 Gum turpentine av.oz. 2 Yellow wax av.oz. 2 Balsam of fir av.oz. 2 Venice turpentine av.oz. 1 Melt the pitch, resin and wax togeth- er, then incorporate, strain when all are melted, and form into sticks. Soothing (Teething) Remedies. These preparations usually have a title like Baby Soothing Syrup, Anise Sooth- ing Drops, Infant Teething Syrup, Baby Soother, Teething Powders, etc. Most of the proprietary preparations of this kind depend for their "soothing" effect upon opium ; others are simply carmina- tive in cases of infantile colic, depend- ing for their value upon anise, some- times combined with fennel, ginger, lac- tucarium, lupulin, etc. The latter two have been credited with sedative (sooth- ing) properties. Inasmuch as the effects of opium are so pernicious, especially upon infants, it is best to refrain from giving formulas containing this agent or its chief alkaloid. There is also the disadvantage with the use of opium, that it obscures the real difficulty; the in- fant may be suffering from a vital or dangerous disease which will result fa- tally if not properly treated by a com- petent physician. Liquids. The dose of these preparations is one- fourth to one teaspoonful according to the age of the child. I. Anise av.oz. i x A Fennel av.oz. V2 Caraway av.oz. Y?. Lupulin dr. 2 Ginger gr. 30 Lactucarium gr. 30 Diluted alcohol sufficient Simple syrup fl.oz. 20 Mix the drugs, reduce to coarse pow- der, percolate with diluted alcohol so as to obtain 12 fluidounces of product and to this add the syrup. II. Anise av.oz. i 1 /a Fennel av.oz. x / 2 J Hops gr. 120 Lactucarium gr. 30 Diluted alcohol fl.oz. 12 Simple syrup, to make fl.oz. 32 Mix the drugs, reduce to coarse pow- der, percolate with the diluted alcohol, and add the syrup. Powders. One powder is to be given to a child 6 months old ; half a powder to a young- er child. III. Make powders each containing Pepsin, saccharated gr. 5 Magnesium carbonate gr. 1 Charcoal gr. J /> Lactucarium gr. 1/6 IV. Make powders each containing Mercurv with . chalk gr. y 2 Magnesium carbonate, heavy... gr. 2 Rhubarb, powder gr. 2 Su^ar, powder gr. 2 Tablets. V. Make tablets each containing: Oil of anise m. 1/134 Ipecac, powder gr. 1/134 Nickel bromid br. 1/134 Codeine sulfate gr. 1/67 Lithium carbonate gr. 1/25 Give one every 5 to 10 minutes as may be required, breaking the tablet into the child's mouth. Stings and Bites, Treatment for. Dog Bites. The bite of a dog is often dreaded on account of the possible danger of rabies. This fear is usually ungrounded, but nevertheless the wound should be cleans- ed, first with soap and water, then with antiseptics, such as carbolic acid water, dilute solution of mercuric chlorid or solution of potassium permanganate. During this cleansing operation,, the wound should be exposed as much as possible. If there is any suspicion that the animal is rabid, the wound should be cauterized. The animal should not be killed, but should be closely confined and be watched to see if it develops symptoms of rabies. If this occurs and 588 THE STANDARD FORMULARY Stings and Bites (Cont'd). it should show within ten days or there is other proof of hydrophobia, the pa- tient should be sent to a Pasteur insti- tute. Insect Stings. The stings of mosquitoes, wasps, bees, spiders and other insects are common in summer time. Apply ammonia water, spirit of camphor, or lead water and op- ium. Camphorated chloral will usually stop the pain. The following, if applied at once, will often prevent inflammation : Salicylic acid gr. 48 Flexible collodion fl.oz. 1 Ichthyol is also an excellent remedy. It may be added to the above collodion mixture, or used in the form of lotion or ointment, or in the following : Ichthyol fl.dr. 4 Ammonia water fl.dr. 4 Camphor water fl.oz. 4 Apply frequently to the inflammation. This is also highly recommended : Olive oil ..fl.oz. I Amomnia water fl.oz. I Oil of turpentine m. 30 Tincture of opium m. 30 Sunstroke or Heat-Stroke. There are two forms of sunstroke (properly called heat-stroke or insola- tion), one a mild form called heat ex- haustion, the other being true sunstroke or thermic fever. Sunstroke may not necessarily be caused by direct exposure to the rays of the sun, but may be due to high atmospheric or artificial temper- ature, especially if this be aggravated by much humidity. Stokers, glass-blowers, bakers, etc., often suffer from it. Pre- disposing causes are ill-health, debility, fatigue, lack of drinking water, intem- perance, improper food, excitement or a previous attack of sunstroke. Heat exhaustion is a mild form of the attack and is not necessarily caused by exposure to the sun. The skin is pale, cold and clammy, the pulse is feeble, and the respiration shallow. While death sometimes results, the patients usually will recover under good treatment. The affected person should be removed to a shady spot and laid on his back, his head should be lowered, his clothes loosened, and cool water lightly sprinkled on his head and chest. Ammonia should be ap- plied to the nostrils and small quantities of stimulants, such as whisky, brandy, aromatic spirit of ammonia, nitroglyce- rin, strychnine, etc., should be adminis- tered. True sunstroke or heatstroke (ther- mic fever) is the serious form of this complaint and may be caused by direct exposure to the sun's rays or to a high artificial temperature. The face becomes purple, the eyes bloodshot, and the veins swollen and corded; the skin is dry and burning, hot to the touch, and the res- piration is rapid and stertorous. Delir- ium is common and the temperature is usually very high, reaching from 105 to 115 deg. F. The danger to the patient is great, death occurring in from 15 to 50 per cent of the cases affected, while those whose lives are saved are with rare exceptions ever afterwards invalids with impaired brain power. While waiting the arrival of a physi- cian, the stricken person should be re- moved to a cool, shady place, laid on the floor or ground, his clothing loosened and ice or ice-water applied, particularly to his head, back of his neck and spinal column. Rubbing the extremities with alcohol and applying 1. ustard poultices to the feet are also recommended. When the temperature of the patient drops to 102 deg. F. (taken by the rectum), he should be rubbed dry, placed in bed, lightly covered, with ice to the head. Excessive dropping of the temperature (collapse or below normal) should be carefully watched for, in which event proper stimulants should be used and applications of hot water bags made to the body. Symptoms of threatened heatstrokes may appear hours or even days before the attack. There is frequently more or less depression, uneasiness or irritability. The respiration may be hurried and the DOMESTIC PREPARATIONS. 589 skin hot and feverish, there is great thirst, headache and dizziness are com- mon, and the sight is affected, sometimes a mere intolerance of light, but often everything seems of a purplish or red- dish color. Later there is a sinking sen- sation at the pit of the stomach, some- times nausea and vomiting and a sense of tightness around the chest. As long as perspiration is free, it is possible to bear a high degree of heat, as the evaporation of the excretion from the surface of the body tends to cool the person. But in very humid weather, both perspiration and evaporation are checked, and if the atmospheric temper- ature reaches or even approaches. 98^ deg. F. there is grave danger of numer- ous cases of heatstroke. It is at such times that people, especially those not in robust health, should exercise the great- est care about exposure, over-exertion, manner of dressing, eating and drink- ing; above all they should avoid alco- holics in any form and everything tend- ing toward depressing physical energy. The food should be light, but nutritious, and meats, fats and heavy pastries should be eschewed. Overloading the stomach with food and drink, especially iced liquids, is harmful. A sponge bath morning and night is better than a pro- longed cold bath, and this applies par- ticularly to infants and children. Con- finement in close rooms is depressing, and if this be unavoidable the rooms, working, living and sleeping rooms, should be well ventilated. The clothing should not be unnecessarily heavy; the hat especially should be light and well- ventilated. Syphilis Remedies. The recommending of remedies for the use of syphilitics does not come within the province of the pharmacist. The formula below, known as Hot Springs Prescription, is given merely be- cause of its more or less extended use. Other remedies which may prove useful are the "blood purifiers" containing po- tassium iodid. Iodine gr. 2 Mercuric chlorid gr. 3 Potassium iodid gr. 480 Comp. tincture of gentian, .fl.oz. 2 Fluid extract of senna fl.oz. 1 Compound syrup of sar- saparilla fl.oz. 8 Water, to make fl.oz. 16 Mix and dissolve. Tape-Worm Remedies. See under Vermifuges. Throat Affection, For. Under this heading are classed such preparations as could not conveniently be placed under the Cough and Cold Remedies. These include tablets or loz- enges and gargles. The former may be called Bronchial Lozenges (or Troches or Tablets), Throat Troches, Voice Loz- enges, etc. Troches. I. Morphine sulfate gr. 10 Ipecac gr. 40 Ginger gr. 40 Tartaric acid gr. 30 Oil of anise gr. 20 Su?ar av.oz. 16 Mix all the dry ingredients, which should be in very fine powder, add the oil, mix again, pass through a fine sieve, and convert into a lozenge mass by add- ing a small amount of mucilage of aca- cia or of gum tragacanth, and then suf- ficient water. Roll the mass out and di- vide into lozenges of suitable size, spread these out on boards or trays in a warm place and when nearly dry turn them over and allow them to dry on the other side. II. Cubeb gr. 140 Potassium chlorate gr. 280 Extract of licorice gr. 150 Pine tar gr. 20 Sugar av.oz. 16 Mix the cubeb, potassium chlorate, ex- tract and sugar, all in fine powder; then incorporate the tar, make into a mass like the preceding, divide into lozenges and dry as before. 590 THE STANDARD FORMULARY Throat Affections (Cont'd). These lozenges have enjoyed some reputation under the name of Pine Tree Tar Lozenges. The licorice, cubeb and tar act as an expectorant and the potas- sium chlorate is intended to relieve sore- ness of the throat. III. Fluid extract pellitory m. 2/3 Pilocarpine hydrochlorid. . .gr. 1/100 Extract of licorice gr. 2 Glycerin m. 1 Sugar, to make gr. 20 This is sufficient for one lozenge, which should be prepared like the pre- ceding. These lozenges give great relief from the uncomfortable sensations of heat and dryness which characterize many acute and chronic affections of the mu- cous membrane of the mouth and and throat. The lozenge should be al- lowed to dissolve in the mouth, and one used every two, three or four hours as necessary. The addition of 2 grains of ammonium chlorid will often be benefi- cial in sub-acute inflammatory conditions of the mucous lining of the respiratory tract, while in more chronic affections 2 or 3 minims of the oleoresin of cubebs will serve a good purpose. Gargles: IV. Compound Sage Gargle : Alum av.oz. ^2 Sage av.oz. 1 Honey oz. 2 Water, boiling fl.oz. 16 Pour the water upon the sage, let stand until cool, strain, dissolve the alum in the liquid, and add the honey. V. Acid Gargle : Acetic acid, 36% fl.oz. 1 Honey fl.oz. 2 Infusion of rose, to make. . .fl.oz. 16 Make the infusion the strength of half an ounce of the dried petals of red rose to one pint of boiling water; dis- solve in this, while hot, the honey, strain and add the acid. This is an excellent gargle for ordi- nary sore throat. VI. Alum Gargle : Alum av.oz. 1 Honey fl.oz. 2 Infusion of rose, to make. . .fl.oz. 16 Dissolve the alum in the infusion, add the honey and strain. This is useful in inflamed conditions of the mouth and throat. VII. Tannin Gargle : Tannin dr. 2 Honey fl.oz. 2 Infusion of rose, to make. . .fl.oz. 16 This is useful in salivation, relaxation of the uvula, etc. VIII. Chlorin Gargle : Potassium chlorate gr. 30 Hydrochloric acid, strong. . .fl. dr. I Tincture of iron chlorid. .. .fl. dr. 1 Water, to make fl.oz. 4' Place the powdered chlorate in a four- ounce bottle, pour upon it the acid, cork the bottle loosely, shake slightly and when the bottle is filled with yellowish fumes of gas, add the water, shake thor- oughly, add the tincture and mix. This is useful in malignant putrid sore throat. IX. Iron Gargle: Potassium chlorate av.oz. 1 Tincture of iron chlorid. .. .fl.oz. 2 Water, to make fl.oz. 16 Mix, dissolve and strain or filter if necessary. X. Guaiac Gargle : Tincture of Guaiac fl.oz. 4 Alcohol fl.oz. 4 Solution of potassa fl.dr. 4 Water, to make fl.oz. 16 XI. Borated Myrrh Gargle: Borax, powder av.oz. 1 Tincture of myrrh fl.oz. 1 Glycerin fl.oz. 8 Water, to make fl.oz. 16 Dissolve the borax in the glycerin and water, by the aid of heat if necessary, and then add the tincture. XII. Carbolic Myrrh Gargle: Carbolic acid gr. 16 Potassium chlorate dr. 4 Tincture of myrrh fl.oz. \ l A Honey fl.oz. 2 Water, to make fl.oz. 16 Dissolve the chlorate in the water, and add the other ingredients. DOMESTIC PREPARATIONS. 591 XIII. Resorcin Gargle: Resorcin dr. 2 Potassium chlorate dr. 2 Glycerin fl.oz. 4 Cinnamon water, to make. . .fl.oz. 16 Dissolve the resorcin and chlorate in a portion of the water, then add the glyce- rin and the remainder of the water. Tobacco Antidote or Substitute. The following is recommended : Licorice root, cut coarse av.oz. 4 Gentian root, cut coarse av.oz. 1 Bay leaves, whole sufficient Water sufficient Make a decoction of the licorice and gentian roots with sufficient water so that it will measure about two pints, when strained. In this decoction mace- rate the bay leaves over night, remove excessive moisture by shaking, lay them into flat sheets, and by pressure form into blocks the shape of tobacco plugs. Tonics. The pharmacist will find it to his ad- vantage to put up for sale some tonic preparation for "building up the system" and promoting appetite. There are a number of such preparations in Part I, such as Beef, Iron and Wine (see for- mula under Wines), the various syrups and elixirs of hypcphosphites (see for- mulas under Syrups and Elixirs), and also under Tonics (Hamilton's, Hensel's and Wood's, in Part I). The prepa- rations mentioned under Bitters in this volume may be offered as tonics, also the celery prepartions mentioned under Nervous Debility Remedies. Other ex- cellent tonics are the following : I. This may be known as Iron Tonic Syrup. Solution of iron "pro- toxide" fl.oz. 4 Fluid extract of cinchona. . .fl.oz. 8 Fluid extract of senna fl.oz. 2 Sodium phosphate av.oz. 2 Tincture of nux vomica. .. .fl. dr. 4 Water, hot fl.oz. 4 Simple elixir, to make fl.oz. 32 Dissolve the sodium phosphate in the water, add the other ingredients, let stand for 24 hours, and filter. II. This preparation may be known as Calisaya Tonic. Cinchona av.oz. 2 Bitter orange peel av.oz. 2 Wild cherry bark av.oz. *4 Cinnamon dr. 1 Calamus dr. 1 Simple syrup fl.oz. 10 Alcohol, water, each, to make fl.oz. 32 Reduce the solids to a coarse powder, and percolate with a menstruum consist- ing of 2 volumes of alcohol and 1 vol- ume of water until 21 fluidounces of percolate is obtained. Add the syrup, let stand a day or two, then filter. III. This may be known as Ginger Tonic. Soluble essence of ginger. . .fl.oz. 8 Comp. tincture of gentian. . .fl.oz. 4 Glycerite of hydrastis fl.dr. 4 Sugar av.oz. 4 Alcohol fl.oz. 10 Water fl.oz. 10 Mix, dissolve by agitation, and filter. IV. This preparation has been known as Hop Tonic. Hops av.oz. 4 Dandelion av.oz. 2 Mandrake av.oz. 1 Buchu av.oz. 1 Alcohol, water, each sufficient Mix the drugs, reduce them to coarse powder and extract by percolation with a mixture of 1 volume of alcohol and 3 of water to make 64 fluidounces of per- colate. V. This has been called Java Tonic. Comp. tincture of gentian. . .fl.oz. 4 Simple elixir fl.oz. 12 Syrup of coffee fl.oz. 16 Toothache Remedies. Formerly all toothache remedies were prepared in the liquid form — "toothache drops" they were termed. Several years ago, pills or pellets, each for one inser- tion into the cavity of the tooth, came into use. These have been succeeded lately by pencils or sticks, called "tooth- ache wax" or "toothache gum," which have become very ponular. These con- sist of a fatty body like yellow or white wax or spermaceti with which is incor- 592 THE STANDARD FORMULARY Toothache Remedies (Cont'd). parated carbolic acid, creosote, chloral hydrate, camphor, etc. This is then formed into small sticks or pencils, or else absorbent cotton is saturated with this mixture, and this is then cut into suitable pieces and formed into similar sticks. Several formulas are also given for liquids containing resinous sub- stances which act as a temporary filling or stopping for the tooth while at the same time the pain is eased. Inasmuch as the public rarely asks for a proprietary toothache remedy, the pharmacist can always "push" his own article ; he may even find it advantage- ous to have several kinds of toothache remedies prepared ready for sale. Drops. The following toothache drops are to be applied on a pledget of cotton. More effective results will follow if the cavity of the tooth be first dried out with a piece of dry cotton. I. Camphor av.oz. 2 Chloroform fl.oz. 5 Oil of cajuput fl.oz. 4 Oil of clove fl.dr. 2 Mix and dissolve by agitation. II. Oil of clove.... , fl.oz. 2 Tincture of opium fl.oz. 3 Spirit of ether fl.oz. 6 III. Chloral hydrate av.oz. l / 2 Camphor av.oz. ]/ 2 Chloroform fl.dr. 4 Ether fl.dr. 4' Oil of clove... fl.oz. 1 Oil of peppermint fl.oz. 1 Alcohol, to make fl.oz. 8 IV. Beechwood creosote fl.oz. 1 Chloroform fl.oz. I Oil of clove fl.oz. I Oil of camphor fl.oz. 1 Temporary Fillers. These liquids are similar to the "drops" and act as anodynes (ease pain), and also contain resinous substances which form a temporary filling or stop- ping for the tooth. Mastic is the favor- ite resin. The "fillers" are used like the "drops" ; applied to the cavity on a pledget of cotton. Wax or Gum. Toothache "wax" or "gum" is a fa- vorite form of toothache remedy. It consists of waxy substance (usually yel- low or white beeswax), sometimes col- ored red by keeping in a melted condi- tion with alkanet root and then straining off the excess of root, mixed with ano- dyne substances like opium, oil of clove, chloral hydrate, etc., then rolled into pen- cils, cut into appropriate lengths, wrap- ped in thin waxed paper, and preserved in small vials (1 or 2-dram size). Or a better way is to immerse cotton in the fatty mixture, then cut and wrap the mass as before. In using cut or pinch off a piece of the pencil, warm gently by rolling between the fingers and insert into the cavity of the tooth, previously drying the latter with a pledget of cot- ton. V. Venice turpentine av.oz.. l / 2 Paraffin oil fl.dr. 4 Salol av.oz. % Yellow wax av.oz. zVa Alkanet, root, sufficient to color. Triturate together the salol, turpen- tine and oil, then add to the wax, previ- ously colored with the alkanet (by melt- ing), allow the mixture to cool and roll into sticks or pencils. VI. Paraffin av.oz. 3 Burgundy pitch av.oz. 3 Oil of clove av.oz. 1 Carbolic acid av.oz. 1 Melt the paraffin and pitch together and add the other ingredients when nearly cold, mix with cotton and cut into short rods, wrap in thin waxed paper, and keep in small bottles. Pellets. These are of similar composition to the "wax." The mass is divided into small pills, one of which is to be insert- ed into the cavity of the tooth to relieve pain. DOMESTIC PREPARATIONS. 593 VII. Opium, powder dr. 2 Pellitory root, powder.. dr. 1 Creosote, enough to farm a mass. Make into pellets weighing about one- half grain each. VIII. Oil of clove drops 40 Oil of cajuput drops 40 Sweet almond oil drops 90 Opium, powder .dr. 3 Belladonna root, powder dr. 3 Pellitory root, powder dr. 3 Yellow wax dr. 4 Melt the wax, incorporate the almond oil, beat in the powders and then the other oils, divide into pills weighing about one-half grain, sprinkle these with powdered clove and keep in bottles or well-closed boxes. Vermifuges. Pharmacists are very frequently asked to recommend some remedy for the ex- pulsion of worms in children. The vari- ous vermifuges are of different forms, such as syrup, solution, lozenge, powder and species. These may be entitled Pleasant Worm Syrup, Santonin Worm Lozenges, Chocolate Worm Syrup, Ton- ic Vermifuge, Ideal Worm Powders, etc. A very common ingredient of these preparations is santonin; other common ingredients are oil or fluid extract of wormseed and pink root. These are us- ually combined with some purgative, such as castor oil, buckthorn, rhubarb, calomel, podophyllin, senna and jalap resin. Another addition sometimes made is some carminative like anise or fennel or the volatile oils of either of these. The above described remedies are in- tended only for pin worms and lumbri- coid worms. Tapeworms usually infest adult persons and reauire much different treatment. Formulas serviceable against the latter are also appended. Inasmuch as worms (except tape- worms) infest children almost exclu- sively, these preparations are made ra- ther weak so that the dose will be rela- tively large. The so-called seat-worms or pin- worms infest the rectal region mostly, and in endeavoring to expel these from children, reliance should not be placed exclusively upon internal remedies but should be assisted by lukeworm injec- tions of infusion of quassia, thymol so- lution, vinegar and water, etc. Liquids. I. Formula of the Illinois Pharma- ceutical Association: Fluid extract of pink root..fl.oz. 5 Fluid extract of senna fl.oz. 3 Oil of anise drops 10 Oil of caraway drops 10 Simple syrup fl.oz. 8 The dose is one or more teaspoonfuls at intervals of 3 to 6 hours, according to the child's age, until purging commences. This formula is that of the old and familiar "compound fluid extract pink root and senna," reduced one-half by the addition of syrup. II. Santonica, fine powder av.oz. 1 Fluid extract of pink root.. fl.oz. 3 Fluid extract of senna fl.oz. 3 Oil of wormseed drops 10 Oil of anise drops 10 Oil of caraway drops 10 Oil of fennel drops 10 Syrupy glucose, to make. . .fl.oz. 16 This must be well shaken each time before using. It is to be used like No. I| III. Santonin gr. 3 2 Alcohol fl-oz. 6 Oil of wormseed fl.dr. 3 Fluid extract of wormseed. fl.dr. 2 Castor oil, to make fl.oz. 16 Dissolve the santonin in the alcohol, add this solution to a mixture of the two oils, and to the whole add the fluid extract. The dose for a child one year old is one teaspoonful twice daily; children of other ages in proportion. Powders. IV. Powders may be prepared, each containing santonin, gr. 1, calomel, gr. 1. podophyllin, gr. 1/12. and sugar, gr. 10 to 20. The calomel may be omitted and the podophyllin increased to t/6 gr., or 594 THE STANDARD FORMULARY Vermifuges (Cont'd), either may be replaced by resin of jalap. The dose for a child one year old is half a powder twice daily; for a child two years old one powder. V. Santonin gr. 10 Podophyllin gr. 4 Rhubarb, powder gr. 15 Sugar of milk gr. 30 Mix well and divide into 15 powders. Give 5 hours apart, on an empty stom- ach, until 3 have been given. Omit a day, repeating the dose if necessary. Lozenges. VI. See Part I (under Troches) for formula for an excellent worm lozenge, frequently called santonin lozenge. The santonin is mixed with sugar and made into lozenges with tragacanth and orange flower water. The dose for a child 1 year old is 1 lozenge night and morning; 2 years old, 2 lozenges; 4 years old, 3; 8 years old, 4; 10 years or more, 5 to 7 lozenges; in all cases to be taken twice daily for sev- eral days, then to be followed by a ca- thartic, castor oil preferred. If the worms are not all expelled, the treat- ment should be repeated. Teas. VII. Spigelia av.oz. 4 Manna av.oz. 4 Senna av.oz. 2 Fennel av.oz. 1 Cut the spigelia and senna, bruise the fennel, mix, add the manna and reduce the whole to a uniformly coarse powder. In using, the above amount is suffi- cient for 7 pints of infusion or "tea," of which half a teacupful is to be given to a child 2 years old morning, noon and night before eating. For Tape Worms. Tape worms generally infest adult persons and the doses here given are in- tended for adults unless otherwise speci- fied. VIII. Oleoresin of male fern drops 30 Pelletierine tannate gr. 1 Glycerin fl.dr. 4 The whole is to be taken in a liberal quantity of sweet milk immediately upon arising in the morning. IX. Pomegranate root bark av.oz. 2 Water sufficient Castor oil fl.oz. 1 Acacia, powder av.oz. ^ Syrup of licorice fl.oz. 1 Mix the bark in coarse powder with 8 fluidounces of water, macerate for 10 hours, then heat on a water bath for 2 hours, express, heat the residue as be- fore for 2 hours with 7 fluidounces of water, express again, mix the two li- quids, evaporate them on a water bath to 4^2 fluidounces, make an emulsion with this and the oil and gum, and fin- ally add the syrup. An adult is to take one-half of this mixture upon arising, subsequently tak- ing a cup of coffee or tea, and following in one-half hour with the remainder of the mixture. Schafhirt's Tapeworm Remedy. X. This remedy was proposed in 1874 by A. J. Schafhirt, a pharmacist of Wash ■ ington, D. C, who claimed great effi- cacy for it. The formula and direc- tions for use are as follows : Pomegranate root bark dr. 4 Pumpkin seed gr. 30 Ergot gr. 30 Oleoresin of male fern dr. 1 Croton oil drops 2 Acacia, powder dr. 2 Bruise the first three substances to- gether thoroughly and boil with 8 fluid- ounces of water for 15 minutes, then strain through coarse cloth. Now rub together the last three ingredients and form into an emulsion with the decoc- tion after it has cooled. The patient may take a light supper, but before going to bed he should purge himself with a large dose (one ounce) of rochelle salt. On the following morn- DOMESTIC PREPARATIONS. 595 ing the mixture is taken at one dose on an empty stomach. In about 2 hours the worm will be voided, but it is best for the patient to sit in a bucket half filled with lukewarm water. Care must be taken not to tear the worm should it be slow in passing, lest the head reat- tach itself. If necessary an ounce of rochelle salt may be taken to hasten ex- pulsion. No bad results are said to fol- low this treatment. The addition to the foregoing mixture of 1 fluidram of chloroform will add to its efficacy. Oleoresin of male fern and mixtures containing it must always be well shaken before using. XL Pumpkin seed, deprived of the outer hard membrane. av.oz. 1 Water fl dr. "» Honey av.oz. 1 Beat the seed and water together in a mortar to a uniform paste, then add the honey gradually, mixing the whole well. The above is recommended for tape- worm in children. No previous fasting is required. In the morning upon aris- ing, the child is to drink a glass of milk ; follow this in 1 hour by one-half of the electuary, in 15 minutes the other half, and follow in another 15 minutes with almost a tablespoonful of castor oil. Vermin Destroyers. See Lice, Applications for. Wart Eradicators. Pharmacists are frequently called upon to recommend or offer some remedy for the eradication of the peculiar excres- cences known as warts. These are pecu- liar in that sometimes a very simple remedy applied but once or twice will cause them to disappear and at other times thev persist indefinitely in spite of all treatment. * Everyone is probably familiar with the application of silver nitrate in sticks, concentrated nitric acid, creosote, car- bolic acid, or salicylic acid in any of the 38 forms of corn cures. Glacial, acetic and dichloracetic acid are frequently employ- ed, while some add salicylic acid in the proportion of 1 in 16 to concentrated acetic acid. Another escharotic solution consists of chromic acid 1 part, water 5 parts. Unna recommends mercurial plaster containing 5 per cent of arsenic. It is also recommended to shave off the wart to the quick and then to apply a compress wet with a saturated solution of ammonium chlorid. A corrosive col- lodion for warts consists of 1 part of mercuric chlorid dissolved in 20 parts of collodion. Other apolications are : Con- centrated hydrochloric acid, solution of antimony chlorid, solution of mercuric nitrate, potassium bichromate, arsenic oleate, copper oleate and formaldehyde. Castor oil and oil of cinnamon are also useful. All of these remedies must be applied once or twice daily until the wart disappears. The outer hard, thick layer of cuticle should always be re- moved before applying anything what- ever. An ointment sometimes recommended is the following: Verdigris gr. 50 Savin, powder .gr. 50 Soap cerate av.oz. 1 The following powder is said to be very effective : Calomel gr. 30 Boric acid gr. 15 Salicylic acid gr. 5 Cinnabar gr. 3 Rub into the wart 2 or 3 times a day. Or use the following: Mercuric chlorid gr. 5 Salicylic acid dr. 1 Collodion rl.oz. 1 In the case of multiple warts, where a large number appear within a short time, there is some constitutional de- rangement, and the patients are usually advised to take Fowler's solution in very small doses, or magnesium sulfate in 5 gr. doses 3 times daily. Children's warts, appearing principally on the hands, may be removed by apply- 596 THE STANDARD FORMULARY Wart Remedies (Cont'd). ing during several days solution of soda or potassa, and then covering them with collodion containing tannin. The same treatment applies for common warts. Erasmus Wilson considers the appli- cation of caustic potassa in stick form to be the quickest and most reliable eradicator, one treatment being all that is usually required. Warts appearing on the skin of elder- ly persons must be looked upon as sus- picious (cancer) and should be shown to a reliable surgeon. Worm Medicines. See Vermifuges. VETERINARY PREPARATIONS Many of the formulas here offered, such as those for condition powders, lin- iments, poultry powders, etc., may be kept on hand in convenient form for counter sale. Many of the prescriptions in this Part are taken from Dieterich's Manual, in which the division dealing with remedies for animals was written by a competent veterinarian. Others are from the ex- cellent works published by the Bureau of Animal Industry of the U. S. Depart- ment of Agriculture. This Part has been divided into the following divisions: Division I — Horse Medicines; Division II— Cattle Medi- cines; Division III — Sheep Medicines; Division IV — Swine Medicines; Divi- sion V — Dog and Cat Medicines ; Divi- sion VI— Poultry Medicines; Division VII— Bird Medicines. DIVISION I— HORSE MEDICINES. The doses mentioned in the following recipes are intended for grown horses, since foals generally require treatment only for those diseases which are pecu- liar to foals. As a general rule the quantities ordered may be adjusted to suit the age of the animal, according to the following proportions : For a colt I year old, 2$ per cent of the full dose; for a 2-year-old, 50 per cent, and for a 3 or 4-year-old, 75 per cent of the full dose. Administering Medicines. Medicines may be administered to horses by mouth or subcutaneously, or injected into the rectum, bladder or va- gina, or insufflated into the nostrils, or they may be applied externally to the skin. Of these, all but the first two are intended to produce local effects only. Substances given by the mouth may be in the form of powders, pills, pastes, or liquids. Powders may be coarse or fine, vary- ing according to the manner in which they are given. Condition powders, for example, need not necessarily be in fine powder; the same applies to other insol- uble powders mixed with the feed, al- though the action of the medicine is more prompt if the powder is very finely divided. Soluble powders may be dis- solved in water and then mixed with the feed or with the drinking water. If they are without disagreeable odor or taste, they are readily taken in this manner. These powders may also be put into cap^ sules and then administered in the same manner as boluses. Large gelatin cap- sules intended for veterinary use are now obtainable from any capsule manu- facturer. Pills ("balls" or boluses), when prop- erly made, are cylindrical in shape, 2 inches in length and about % inch in diameter. They should be soft, so as to be easily compressible. They should pre- ferably be fresh, but, if necessary to keep them for some time, they should be made up with glycerin or some such agent to prevent them from becoming too hard. Boluses are preferred to drenches when the medicine is extremely dis- agreeable or nauseating, when the dose is not too large, when it is difficult to administer liquid to the horse, or when the medicine is intended to act slowly. Some substances cannot or should not be made into boluses, such as those 598 THE STANDARD FORMULARY Giving Medicine (Cont'd). given in large doses, or oils, or caustic substances, unless the latter be in small dose and diluted and thoroughly mixed with the vehicle. Substances suitable for making into boluses can be made into a mass by means of glycerin, glucose, syrup, honey, powdered soap and a small amount of water, etc. Paper is sometimes wrapped around boluses when given, but this is necessarv only when they are so sticky as to adhere to the fingers, and no well- made bolus should have this fault. Pa- per used for this purpose should be thin but tough. In giving a bolus, untie the animal, open his mouth, grasp his tongue firmly, pull it forward gently, and lay the bolus, previously slightly moistened, as far back on the tongue as possible. On re- leasing the tongue, it is drawn back into the mouth and carries the bolus with it. The mouth should be kept closed for a minute or two. There should always be a pail of water at hand to offer the horse after administering a bolus. This precaution will prevent the bolus from being coughed out or becoming lodged in the gullet. Pastes, or electuaries, are soft solids made by mixing liquid medicines with nowdered licorice root or ground flax- seed, or solid medicines with honey, syr- up, molasses, or water, as may be neces- sary. In using they are spread on the tongue, teeth or gums by means of a wooden saddle or a long-handled spoon. Liquids may be given as drenches when the dose is large, or they may, when but a small quantity is adminis- tered, be injected into the back of the mouth with a hard-rubber syringe or be poured on the tongue from a small vial. When giving a drench, care must be taken to use the proper amount of oil or water as a diluent, as more makes the drench bulky and is unnecessary. Insoluble medicines, if not irritant or corrosive, may be given simply suspend- ed in water, the bottle to be well shaken just before administering the drench. The bottle used for this purpose should be clean, strong, taoering (without shoulders), and of a size to suit the amount given. Anaemia Medicines. Anaemia is often due to lack of exer- cise in the open air; this condition is most marked in young animals. It may also be due to improper food. Treat- ment consists in iron and arsenic, giving green food if possible, and indulging in light exercise in the open air. The horse should be sent to pasture for a time, if i possible. I. Sulfur av.oz. 2 Potassium bicarbonate ....av.oz. I Sodium chlorid , av.oz. 20 Give one tablespoonful with each meal. II. Black antimony av.oz. 1 Ferrous sulfate av.oz. 1 Sulfur av.oz. 2 Calamus av.oz. 2 Sodium sulfate av.oz. 6 Sodium chlorid av.oz. 8 Reduce all to powder and mix well. Give one tablespoonful with each meal. III. Fowler's solution : Give one tablespoonful once daily upon bread. Appetite, Loss of, For. Loss of appetite is often the result of disorders of digestion and may be the accompaniment or precursor of other more serious affections. The appetite may be improved by giving bitter or aro- matic substances, or else saline sub- stances. The Condition Powders mentioned in this division are useful for improving the appetite. I. Black antimony av.oz. ^ Crude tartar (argols) av.oz. 1 Caraway seed av.oz. 2 Mustard seed av.oz. 2 Rye flour av.oz. 2 Calamus av.oz. 4 Gentian av.oz. 4 HORSE MEDICINES 599 Juniper berries av.oz. 4 Water sufficient Mix the drugs in powder form with enough water to make soft mass or paste. Smear one tablespoonful of this on the horse's tongue three times a day. II. Gentian root av.oz. 4 Sodium sulfate av.oz. 2 Sodium chlorid av.oz. 1 Sodium bicarbonate av.oz. 1 Give 2 tablespoonfuls with each meal. III. See also Condition Powders. Bee, Wasp, Hornet Stings. These are more irritating than the bites of flies, partly because the barbed sting is left in the wound and partly be- cause of the character of the venom. When a swarm attacks an animal the result may be fatal. Treatment consists in the application of ammonia water; a solution of sodium bicarbonate; a solu- tion of potassium permanganate, 2 grains to the ounce; or lead acetate, 2 drams, tincture of opium, 1 fluidounce, and water, 1 pint. The imbedded sting should be extracted. Bladder Inflammation, or Cystitis. Cystitis may be caused by abuse of irritant diuretics, such as cantharides, turpentine, resin, etc., by the presence of stone in the bladder, by the introduction into the bladder, of an uncleaned cathe- ter, by the presence of acrid plants in the fodder, etc. Treatment consists first in the removal of the cause, such as the cantharides or other blistering agent from the skin, or the extraction of stone or gravel. If the urine has been re- tained and decomposed, it must be com- pletely evacuated through a clean cathe- ter and the bladder thoroughly washed out with a solution of one dram of borax to a quart of tepid water. This must be repeated twice daily until the urine no longer decomposes. The diet must be light, such as bran mashes, roots and fresh grass, and the drink im- pregnated with linseed or slippery elm tea. When the acute symptoms have subsided, a daily dose of 1 fluidram of fluid extract of buchu and V* fluidram of fluid extract of nux vomica will serve to restore lost tone. See also Urinary Diseases. Blind Staggers. See Staggers. Blisters. I. Cantharides, fine powder, .av.oz. % Euphorbium, fine powder, .av.oz. % Corrosive sublimate av.oz. % Mercurial ointment av.oz. 2 Linseed oil fl.dr. 4 Sulfuric acid fl.oz. 1 Nitric acid fl.oz. 1 Oil of turpentine fl.oz. 4 Petroleum fl.oz. 2 Add the sulfuric acid gradually to the linseed oil, then add the nitric acid very gradually, and after that the turpentine and petroleum. Let stand for several days, decant from residue, and mix with the decanted liquid the mercurial oint- ment, to which have previously been ad- ded the corrosive sublimate, cantharides and euphorbium. Extreme care must be taken, in mix- ing the acids and oil, to add the acids very slowly, with constant stirring, to the oil contained in a broad vessel, such as an evaporating dish. II. Red iodid of mercury gr. 60 Oil of cajuput gr. 60 Petrolatum gr. 480 III. A liquid blister : Cantharides av.oz. 1 Oil of turpentine fl.oz. 8 Water of ammonia fl.oz. 4 Olive oil fl.oz. 2 Oil of sassafras fl.oz. 1 Macerate for several days, then strain. Hager devised the following for vet- erinary and farmers' use. It keeps sores clean, kills lice, cures scab and itch, and keeps flies, mosquitoes and such insects from animals : Salicylic acid dr. 2 Borax dr. 2 Caustic soda dr. 4 600 THE STANDARD FORMULARY Blisters (Cont'd). Aloes dr. 4 Oil of anise fl.dr. 1 Oil of spike fl.dr. 4 Oleic acid, crude fl.oz. 1 Gum benzoin av.oz. 1 Water fl.oz. 6 Alcohol fl.oz. 12 Carbolic acid, crude fl.oz. 30 Rub the benzoin, aloes and salicylic acid to a fine powder, and add them to the oils dissolved in the alcohol. After a dav's maceration, add to the mixture the oleic acid, the soda and the borax dissolved in the water, and, lastly, the carbolic acid. Shake the whole well for half an hour, and after a week's macera- tion in a cool place decant the clear liquid. For use shake well with twice its bulk of water, and add 100 to 120 times its bulk of water, stirring thoroughly. For scab and itch, dilution with only 30 or 40 times its bulk is necessary. Catarrh, Bronchial, For. Bronchial catarrh usually begins with fever and is generally accompanied by coughing, and the discharge of purulent matter from the nose. If the dry cough does not soon loosen, and there is no nasal discharge, the fomentations rec- ommended under "Glanders" should be employed. These fomentations should not be continued longer than necessary to induce the discharge, as otherwise harm may result to the nasal mucous membrane. In addition to using the medicines mentioned below, warm appli- cations should be bound around the throat and warm drinks should be ad- ministered I. Ammonium chlorid av.oz. 1 Fenugreek gr. 400 Fennel gr. 400 Marshmallow av.oz. 3 Reduce all to powder and mix well. Give in 2 doses in warm meal or in warm "soft" food. II. This is for chronic bronchial catarrh : Sodium sulfate av.oz. 4 Sodium chlorid av.oz. 4 Sodium bicarbonate av.oz. 2 Licorice root av.oz. 2 All should be in powder and should be well mixed. Give 1 tablespoon ful with each meal. III. Mercurial ointment av.oz. 2 Suet av.oz. 3 Oil of henbane av.oz. 5 To be applied to the throat every morning and evening. Catarrh, Nasal, Remedies for. Nasal catarrh may be an ordinary "cold in the head" or it may develop into a chronic catarrh. The former is not serious except in so far as it may lead to something worse or become chronic. An ordinary catarrh requires simply rest for a few days and the in- halation of the vapors of boiling water. The latter treatment is to be repeated several times daily. When the disease becomes chronic, it requires persistent medical treatment. Mineral tonics and local medications are of the most value. For eight days give the following mixture : Reduced iron av.oz. 3 Xux vomica av.oz. 1 Divide into 16 powders. Give one powder mixed with the food twice a day. Arsenous acid (or ordinary white arsenic) in doses of 3 to 6 grains three times daily is a good tonic for such cases. Sulfur burnt in the stable is a valuable adjunct, care being taken that the gas is well diluted with air so -as not to suffocate the animal. Chlorinated lime sprinkled around the stall will also be beneficial. It is advisable to keep a quantity of it under the manger so that the horse inhales the odor when eating ha". The horse may be made to inhale the vapor of creolin or compound tinc- ture of benzoin by adding 2 ounces of either of these liquids to some hot water contained in a pail and holding to the horse's nose. The animal's nose should be kept HORSE MEDICINES 601 washed, and the discharge cleaned from the manger and stalls. Cathartic Medicines. It is frequently necessary to give a cathartic to a horse, as this animal can- not, like some others, remain constipated long without serious consequences. I. Cape aloes av.oz. i Ginger dr. 2 Potassium carbonate dr. 1 Gamboge dr. 1 Oil of fennel drops 20 Make into a mass by means of pow- dered soap and water, roll into a cylin- der about 2 inches long, and cover with gelatin or with thin paper, like tissue paper, suitably oiled or greased to pre- vent the adhesion of the mass to the paper. II. Cape aloes av.oz. 1 Ginger dr. 2 Potassium carbonate dr. 1 Croton oil drops 10 Oil of anise drops 30 Water fl.oz. 8 Linseed oil fl.oz. 8 Tincture of opium fl.dr. 4 Powder the aloes and ginger, add the potassium carbonate, mix with the water, add the oils of anise and croton, then the tincture and finally the linseed oil. To be given at one dose. In cases of unusual weakness or prostration of the animal, the croton oil may be omitted. In putting up this formula in large quantity for general sale, it would be better to substitute powdered gamboge for croton oil, using in the prescription above named 60 grains. III. See also Colic Remedies and Constipation Cure. Colic Bemedies. Colic is probably the most common ailment of horses. It is usually due to obstinate constipation and retention of urine; occasionally it is caused by diar- rhea. In the former instance, purgative and carminative remedies should be ad- ministered and warm applications should be made. If the colic is due to diarrhea, alum and similar substances with carminatives are employed. The usual treatment is by warm ap- plications to the back, abdomen and legs, also frictions with a turpentine mixture, until perspiration ensues. Then fasten blankets to the back and abdo- men to allow the horse to remain per- spiring for a time. In the meantime, one of the remedies mentioned below is to be used. In case there is constipation, the bowels should be emptied by means of the hand, previously well oiled; in 15 minutes give an enema of warm chamo- mile tea. As soon as the bowels and bladder are emptied, the colic will dis- appear. If the abdomen of the horse is dis- tended with gas, the animal should be taken out for a short trot. I. This is an application for the body as directed above: Oil of turpentine fl.oz. 4 Ammonia water fl.oz. 1 Alcohol fl.oz. 15 II. The usual remedy for colic is a mixture of one fluidounce each of lauda- num and sweet spirit of nitre. This is best given with a pint of raw linseed oil which acts as a cathartic. III. Chlorodyne fl.oz. 1 Spirit of nitrous ether fl.oz. 2 Linseed oil, raw fl.oz. 13 Give at one dose, repeating in 2 hours if necessary. IV. Hypodermic injections containing eserine may be employed, instead of in- ternal remedies, to relieve colic due to constipation ; these produce more prompt results. A. Eserine sulfate gr. i T ^ Distilled water fl.dr. 1 J 2 Dissolve and inject at one Jose. B. Eserine sulfate gr. i T 2 Pilocarpine hvdrochlorul gr. 5 Distilled water fl.dr 602 THE STANDARD FORMULARY Colic Remedies (Cont'd). Use at one injection. The latter 'is particularly valuable when the colic is due to obstinate constipation. When using these injections, the ex ternal treatment should be the same as otherwise. Enemata may also be given. Internally warm chamomile tea only may be given. V. Tincture of opium fl.oz. I Ether fl.oz. I Alcohol fl.oz. i% Oil of anise drops 30 Give one tablespoonful every 15 to 30 minutes in a pint of water. Also make energetic frictions of the abdomen with oil of turpentine. VI. For colic caused by constipation : Magnesium sulfate av.oz. 18 Althaea av.oz. sY 2 Rye flour av.oz. 3^2 Add water or simple syrup to form a mass. Give one-half of this mass and repeat the dose in one-half hour. VII. For colic due to constipation and re- tention of urine : Sodium sulfate av.oz. 18 Juniper berries, coarse pow- der av.oz. 3 >2 Rye flour av.oz. s J / 2 Make into a mass or paste with sim- ple syrup or glucose. This is to be administered like the preceding. VIII. For colic due to diarrhoea. Alum dr. 5 Althae av.oz. V/2 White oak bark av.oz. 1^ Juniper berries av.oz. i l / 2 All of these should be in powder and should be formed into a mass with molasses. IX. The U. S. Bureau of Animal In- dustry recommends chloral hydrate in both "cramp" ( spasmodic j and "wind" (flatulent) colic, the dose being one av. ounce dissolved in a pint of water. For cramp colic, use a mixture of 2 fluid- ounces each of sulfuric ether and lauda- num with 8 fluidounces of raw linseed oil. Another mixture for this purpose is 2 fluidounces each of sulfuric ether and alcohol with 8 fluidounces of water. It is important to give a purgative, either a "horse ball" of aloes or else a full dose, say a pound, of epsom or glauber's salt, dissolved in water. Ene- mas of warm water, or in wind colic, 1 to 2 fluidounces of oil of turpentine with 8 fluidounces of raw linseed oil are rec- ommended. In wind colic, diluted alcohol or whis- ky may be given, or aromatic spirit of ammonia in 1 -ounce doses at short inter- vals. Condition Powders. These preparations are also known as "Horse Powders," "Horse and Cattle Food" and "Stock Food." Pharmacists frenuently dispense preparations of this character made by themselves ; as titles, they may select those given above, also such as "Maud S. Condition Powder," "Prairie Condition Powder," "Farmer's Condition Powder," "Arabian Condition Powder," "0. K. Condition Powder," etc. The following list will be of interest, as well as of service, in determining what ingredients may enter into the composition of a condition powder: Alteratives. Sodium hyposulnte, sulfur. Diuretics and Diaphoretics. Alum, black antimony, buchu, cream of tartar, pure and crude, juniper ber- ries, lobelia, potassium nitrate, resin. Expectorants. Blood root, potassium chlorate, ele- campane, licorice root, lobelia, resin. Tonics. Iron carbonate, gentian, cinchona, pop- lar bark, iron sulfate. Aromatics and Correctives. Anise, sodium bicarbonate, camphor, cascarilla, capsicum, cumin seed, fenu- HORSE MEDICINES 603 greek, ginger, grains oi paradise, mus- tard, salt, sassafras. Emollients and Laxatives. Aloes, magnesium sulfate, flaxseed meal, sodium sulfate, oil cake meal. Sedatives. Asafetida, digitalis, skunk cabbage, valerian. The usual dose of these powders is about one tablespoonful 2 or 3 times daily in food. I. Black antimony . Sulfur Elm bark Resin Potassium nitrate Anise seed Reduce all to powder and mix well. II. . .av.oz. 12 . .av.oz. 10 ..av.oz. 5 ..av.oz. 2 ..av.oz. 2 ..av.oz. 1 Elecampane av.oz. 8 Fenugreek av.oz. 8 Linseed . . . .av.oz. 8 Juniper berries av.oz. 8 Poplar bark . . . .av.oz. 8 Resin av.oz. 8 Licorice root . . . .av.oz. 6 Ginger av.oz. 6 Sodium sulfate . . . .av.oz. 6 Sodium chlorid . . . .av.oz. 6 Sulfur . . . .av.oz. 6 Copperas . . . .av.oz. 6 Sodium carbonate . . . .av.oz. 4 Gentian . . . .av.oz. 4 Black antimony . . . .av.oz. 2 Potassium nitrate . . . .av.oz. 2 Coriander seed av.oz. 2 Valerian . . . .av.oz. 2 Blood root av.oz. 1 Lobelia av.oz. 1 Mandrake root av.oz. 1 Dried alum av.oz. 1 Reduce all to powder a id mix well. This is a sample of son le recipes that are considered valuable. III. Fenugreek . . .av.oz. 16 Sulfur . . . av.oz. 8 Cream of tartar ...av.oz. 4 Potassium nitrate ...av.oz. 4 Licorice root ...av.oz. 4 Black antimony ...av.oz. 2 Gentian . . . av.oz. 1 Anise . . .av.oz. 1 Common salt ...av.oz. 1 Reduce all to powder and mix well. . . .av.oz. 1 . . .av.oz. 4 . . .av.oz. 4 av.oz. 7 IV. Sodium chlorid . . Fenugreek Licorice root . . . Flaxseed, ground Reduce all to powder and mix well. Give one ounce daily. V. Black antimony av.oz. 1 Resin av.oz. 1 Cansicum av.oz. 1 Gentian av.oz. 2 Fenugreek av.oz. 2 Sulfur av.oz. 2 Saltpeter av.oz. 2 Cream of tartar av.oz. 2 Ginger av.oz. 2 Licorice av.oz. 3 Reduce all to powder and mix well. Dose, 1 tablespoonful once or twice a day. VI. Magoffin's formula : Alum, powder lb. 3 Saltpeter lb. 3 Asafetida lb. 3 Copperas lb. 5 Rosin lb. 5 Sulfur lb. 5 Oil-cake meal lb. 10 Reduce all the drugs to powder and mix the whole thoroughly. Directions: Give a horse a heaping tablespoonful every morning, in wet oats or provender, for 6 or 8 days; after that, the same dose every other day for a few days. The same dose may be given to a cow or hog. VII. Condition Powder, Darby's : Sodium sulfate av.oz. 8 Sulfur av.oz. 4 Fenugreek av.oz. 4 Gentian av.oz. 2 Black antimony av.oz. 2 Reduce all to powder and mix well. Constipation Cures. Constipation is usually caused by im- proper feeding, but may be the result of other conditions ; it may also be the cause of colic (see Colic Remedies). In ordinary constipation cathartic remedies and enemas are indicated. See also Cathartics. 604 THE STANDARD FORMULARY Cough Remedies. Coughs should be treated by binding warm applications about the throat or making fomentations as described under "Glanders." If the nasal secretion is too copious, it may be checked by giving a powder containing some lead acetate. In addition, the following remedies may be employed : I. Antimony sulfid av.oz. I Licorice root av.oz. 2 Sodium chlorid av.oz. 5 Mix all in powder form. Give 2 tablespoonfuls after each meal. II. Ammonium chlorid av.oz. 5 Antimony sulfid av.oz. 1 Cream of tartar (or argols) av.oz. 2 Linseed meal av.oz. 10 Divide into 8 powders and give one of these in a mucilaginous or starchy drink twice a day. III. Ipecac av.oz. 1 Squill av.oz. 1 Licorice av.oz. 2 Mix into 7 balls with syrup or honey. Give one 3 times a day. IV. Aconite leaves, powder dr. 6 Digitalis, powder dr. 4 Anise, powder dr. 4 Arsenic gr. 4 Mix, and divide into 6 powders. Give one every night in food. This remedy is useful in chronic cough. V. For poultice : Mustard, ground or powder. av.oz. 3 Wheat bran av.oz. 9 Mix well. In using, mix this powder with water warmed to about 75 deg. C. and apply it in the usual manner for poultices. The addition of the mustard makes the poultice somewhat of a counter-irri- tant but without being as irritating as a mustard plaster. Diarrhea Remedies. Diarrhea is often the result of "catch- ing cold/' but may also be the precursor or accompaniment of other disorders. Mild cases may be cured by giving dry fodder and warm drinks or adding flour to them. In severer cases, aromatic and bitter substances may be administered and in some cases astringents may be required. Applications should be made to the entire abdomen ; the whole body should be rubbed vigorously and then covered with blankets so as to retain the perspiration produced by the rubbing. This rubbing of the entire body should be repeated every 3 hours. I. For mild cases : Alum av.oz. 1 Calamus root av.oz. 2^> Angelica root av.oz. 2H Wormwood av.oz. 2^2 Rye floor av.oz. 2.y 2 Water sufficient All the drugs should be in powder and enough water should be added to form a paste. Place a lump, the size of a hen's egg, on the tongue every 5 hours, between meals. II. For mild cases: Iron sulfate, powder av.oz. Yz Althaea, powder av.oz. 3 Water, sufficient to form a mass. Divide into two doses, and give these within 3 hours of each other. III. For severe cases : Iron sulfate, powder av.oz. 1 Alum, powder av.oz. 1 Oak bark (red or white) . . .av.oz. 2 Calamus root av.oz. 2 Rye flour av.oz. 4 Water, enough to form a mass or paste. Place a piece the size of a hen's egg upon the tongue every 2 hours. IV. For obstinate cases : Tannin av.oz. 1 Althaea, powder av.oz. i J /2 Simple syrup or molasses, .sufficient Divide into 3 pills and give 1 pill every evening. HORSE MEDICINES 605 V. The U. S. Bureau of Animal In- dustry recommends giving an oleaginous purge, such as castor oil or raw linseed oil, the former preferred. If the diar- rhea still continues after the medicine has acted, give half-dram doses of sul- furic acid in 8 fluidounces of water 2 or 3 times daily. Good results often fol- low the use of powdered opium, 2 drams, bismuth subnitrate, 1 ounce, 3 times daily. But by all means the water and feed the horse is getting should receive attention, as these are usually at fault. Distemper Remedies. See Strangles, Remedies for. Diuretics. See Urinary Diseases, Remedies for. The following may also be recom- mended : Potassium acetate av.oz. y 2 Fluid extract of buchu fl.oz. 1 Fluid extract of uva ursi. .. .fl.oz. 1 Gin fl.oz. 1 Tincture of opium fl.oz. 1 Sweet spirit of nitre fl.oz. 2 Glycerin fl.oz. i l / 2 Water fl.oz. 8 Give 1 to 2 fluidounces at a dose. It sometimes happens that the animal is simply afflicted with a slight disturb- ance of the kidneys, producing what is termed by horsemen and veterinary sur- geons yellow water; for this ailment a simpler remedy is demanded, and the following will prove of service: Potassium nitrate av.oz. 1 Fluid extract of buchu fl.oz. 2 Sweet spirit of nitre fl.oz. 4 Anise water fl.oz. 9 Give 1 or 2 tablespoonfuls at a dose, night and morning, for 3 days, and then in the morning only, for one week. Dysentery Remedies. Dysentery, sometimes called "bloody flux," is more common in colts than in full-grown animals. In colts, unless given prompt attention, it often proves fatal in a few days. Opium is given in- ternally and may be combined with calo- mel. Externally the animal should be rubbed frequently and warm applications made. Opium gr. 75 Althaea av.oz % Water, to make a mass. Divide into 5 pills. Give one pill every 5 hours. II. Tannic acid av.oz. l / 2 Licorice root, powder ..av.oz. 1 Simple syrup, to make a mass. Divide into 5 pills. Give one pill every 5 hours. III. For external use : Tincture of capsicum fl.oz. 1 Spirit of mustard fl.oz. i l / 2 Spirit of camphor fl.oz. 8 Apply a tablespoon ful to the abdomen 3 times daily, rubbing for 5 minutes with a woolen cloth. Dyspepsia and Indigestion Remedies. Dyspepsia may be due to loss of ap- petite or to too hasty eating, causing im- perfect mastication. The affected ani- mal will become emaciated, it will be flatulent ("wind on the stomach"), and the dung will have a fetid odor ; in the latter undigested oats will be observed. If the animal is addicted to too hasty eating, the oats should be mixed with chopped hay before feeding. The fol- lowing recipes will be found valuable : I. Sodium chlorid av.oz. 5 Sodium bicarbonate av.oz. 2 Calamus root, powder av.oz. 1 Reduced iron gr. 90 Give I tablespoonful with each meal. II. The U. S. Bureau of Animal In- dustry states that if the indigestion is accompanied by distention of the stom- ach and bowels with gas, the following is to be used: Sodium bicarbonate, Ginger, powder, Gentian, powder, each, equal parts. This mixture is to be given in heaping tablespoonful doses twice a day. before feeding. Or the powder may be mixed with half a pint of water and given as a drench. As a digestive tonic, the following is good: 606 THE STANDARD FORMULARY Indigestion (Cont'd). Sodium sulfate av.oz. 8 Sodium chlorid av.oz. 4 Sodium bicarbonate av.oz. 2 Give a heaping tablespoonful with each feed. Other things should be looked after. For example, if the teeth are sharp and irregular, they should be filed down; if any are decayed, they should be extract- ed; if the horse is addicted to ravenous eating or to bolting of food, the feed should then be given from a large man- ger so that the grain may be spread out and the horse thus compelled to eat more slowly. Epizooty Remedies. See Influenza Remedies. Eyes, Inflammation of the, For. Inflammation of the eyes may be due to mechanical injury or to a cold. If the conjunctiva is affected, the inflam- mation is of catarrhal character; if the cornea is affected, it is of rheumatic ori- gin. The eye must strictly be protected from bright light; it should be bathed three times daily with water not too cold and covered with cloths moistened with lead water. In severe cases, aloes pills should be given sufficient to produce purgation, the cheeks should be rubbed with a counter-irritant ointment, and in- stead of using lead water, apply the fol- lowing solutions : I. Zinc sulfate gr. 16 Distilled water fl.oz. 16 Mix and dissolve. Fold a cloth so as to form four thick- nesses, lay over the inflamed eye and moisten with the solution; repeat the moistening every 2 hours. II. Zinc sulfate gr. 15 Crocated tincture of opium. fl. dr. iH Infusion of elder flowers. . .fl.oz. 16 Mix and dissolve. Tincture of opium may be substituted for the crocated tinc- ture. The infusion may be prepared from I av. ounce of drug; plain water may be substituted, if desired, for the infusion. This preparation is to be applied like the preceding. III. Silver nitrate gr. 5 Distilled water fl.oz. 2 Mix and dissolve. Drop 2 or 3 drops into the eye once daily after washing with water. IV. For opacity of the cornea: A. Calomel gr. 60 Sugar of milk gr. 60 Mix well, rubbing to a very fine pow- der. Take as much as will lie on the point of a knife and blow into the eye, first washing the latter. Repeat every second day. B. Zinc oxid gr. 6 Sugar gr. 60 Prepare and use like the preceding. Farcy, Remedies for. See Glanders and Farcy, Remedies for. Fever Medicines. Fever is usually the result of other diseases; it is frequently accompanied by increase in the pulse rate. The nor- mal temperature of the horse is Z7 to 38 deg. C. (97 to 98 deg. F.), but may rise in fevers to 40 deg. C. (104 deg. F.), or even to 41 (106 F.). Fever generally begins in the horse with a chill, the hair stands erect, the muscles shiver, the feet and ears feel cold while the rump feels hot. I. Potassium nitrate av.oz. 1 Sodium sulfate av.oz. 10 Rye flour av.oz. 4 Make into a mass or paste with simple syrup or molasses. Give one-half in the morning and the other in the evening. HORSE MEDICINES 607 II. Sodium salicylate av.oz. 3 Licorice root av.oz. 2 Rye flour av.oz. 2 Make into a mass with water. Give one-half of this mixture one morning and the remainder the follow- ing morning. III. For Malarial Fever: Quinine sulfate or muriate, .av.oz. 1 Althaea av.oz. 3 Make into mass with syrup and divide into 4 pills. Give the four pills during two consec- utive days, one each morning and even- ing. IV. For Rheumatic Fever: Salol dr. 5 Althaea dr. 5 Make a mass with simple syrup or glucose and divide into two boluses. Both pills are to be given at one dose. V. These pills are of special value against the fever accompanying influ- enza, glanders, etc. Acetanilid dr. 5 Althaea av.oz. 1 Form into a mass with simple syrup and divide into 2 boluses. Give 1 bolus in the morning and 1 in the evening. Flies, Treatment for. See the formula under Mosquito Oil, which makes an excellent preparation for warding off the attacks of flies. Some species of flies attack horses and suck their blood, producing great annoy- ance. These insects not only suck the blood, but also instil an acid poison into the skin, and may transfer infectious germs from one animal to another. Va- rious means are used to prevent these attacks such as applying the above-men- tioned "mosquito oil," sponging with a decoction of tobacco leaves, dusting with insect powder, removing all manure heaps, mixing the manure with chlori- nated lime, etc. For the poisoned bites apply ammonia water, or a solution of 1 part of carbolic acid in 20 of glycerin or sweet oil, or 2 drams of sodium bicar- bonate and 1 dram of carbolic acid in a quart of water may be used. See also Gnat Oil. The following is highly recommended : Oil of pennyroyal fl.dr. 4 Oil of lavender fl.dr. 2 Carbolic acid fl.dr. 1 Fish oil, to make fl.oz. 16 Founder or Laminitis, Remedies for. This disorder of horses is very com- mon. Usually the soft parts of the hoof are affected; the animal then steps with exceeding caution; it lies down mostly in the stall, and groans frequently; the pulse-rate is increased, and sometimes there is fever. Usually either front feet or hind feet only are affected. Mild cathartics should be given and care should be taken that there is a nor- mal flow of urine; antifebrile remedies should be administered. As there is us- ually constipation, the bowels should be emptied by means of salt water ene- mata; when these are used, cathartics should, of course, be omitted. External stimulating liniments or counter-irritant ointments should be applied. The ani- mal should be fed only on half rations and the food should be of an easily di- gestible character. I. Camphor, powder av.oz. *4 Potassium nitrate, powder, .av.oz. 2 Juniper berries, crushed av.oz. 4 Rve flour av.oz. 4 Sodium sulfate, powder av.oz. 8 Water sufficient Make into an electury and give one- fourth of the whole every 5 hours. II. For the fever: Aloes, powder av.oz. 1 Sodium sulfate, powder av.oz. 8 Rye flour av.oz. 4 Water sufficient Make an electuary, divide into 2 parts and give 3 hours apart. III. For shoulder lameness, use the following : Ammonia liniment fl.o Oil of turpentine tl.oz. I Apply twice a day. IV. Regarding acute laminitis (ac- oos THE STANDARD FORMULARY Pounder (Cont'd). cording to the U. S. Bureau of Animal Industry), what has been called the "American treatment" is simple and ef- ficient. It consists solely in the exhibi- tion of large doses of ootassium nitrate (4 ounces in a pint of water every 6 hours) and the continued application of cold water to the ankles and feet. The disease frequently subsides in a week. In subacute forms, smaller doses, say H to 1 ounce, of potassium nitrate- should be given. The water used for bathing should have a temperature of 4*5 to 50 deg. F. The water may be in a tub in which the animal can stand, or if the animal is ly- ing down, swabs may be used which should be wet every half hour with the water. Tincture of aconite may be given in conjunction with the nitre when the heart is excited and beats stronglv, in 10-drop doses every 2 hours. Galls or Blisters, For. Blisters or galls are brought about by badly fitting harness or saddles, which produce local sores very difficult to cure. The sores should be washed two or three times a day with soap and water ; the ointment should then be applied two or three times daily on clean soft cloths. I. Salicylic acid 5i '° 7 Zinc oxid Water Mutton tallow Lard II. Salicylic acid av.oz. Mutton tallow av.oz. 2^ Lard av.oz. 3 Lead plaster av.oz. 4 III. Tannin av.oz. 1 Camphor, powder av.oz. 2 Zinc oxid av.oz. 3 Mix and sift through a fine sieve. Sprinkle on the raw or injured sur- faces, after having washed them with tepid water and carbolic soap. av.oz. /2 av.oz. 1 av.oz. 1 av.oz. 2}/ 2 av.oz. 5 ^ IV. A most valuable remedy in vet- erinary practice for all kinds of sores, bruises, cuts, or whenever the skin is broken is i-he application of Friar's Bal- sam, the compound tincture of benzoin of the U. S. P., and may be profitably put up under some appropriate name and sold by pharmacists. V. The U. S. Bureau of Animal In- dustry mentions other remedies, such as a solution of 10 grains of silver nitrate in a fluidounce of water; 20 grains of lead acetate or zinc sulfate to an ounce of water; or 1 part of carbolic acid with 15 parts of glycerin. Saddles or other parts of the harness should be made to fit properly, and should be cleaned and oiled to remove all dirt and made soft and pliable. Any simple astringent wash or powder will effect a cure provided the sores are not irritated by friction. Glanders and Farcy, Remedies for. This is a rather common disease and may result from contracting cold as well as from infection. The two forms are distinguished as a benign and a malig- nant form ; the remedies mentioned be- low apply only to the former. The malig- nant form of glanders is a highly danger- ous and infectious disease and should be treated only by those well versed in its treatment. Mallein, a serum, is used to determine the presence of the disease. The diseased horse is languid, per- spires easily, has diminished aopetite and a cough. From the inflamed nostrils flows a discharge, watery at first, later becoming thick and mucous. When the secretion assumes the latter character, a swelling appears in the throat, which in- terferes with mastication. This swelling will become purulent, break open and discharge, and subsequently will heal, after which the horse appears quite well. Farcy and glanders are the same dis- ease but different manifestations. Glan- ders refers to the general character of the disease while farcy refers to the nodules and eruptions on the face. HORSE MEDICINES GOO Treatment consists in keeping the ani- mal warm by covering with a woolen blanket, also binding a cloth about the throat. Internally give mild cathartics, and assist the process of the swelling in the throat by the application of stimulat- ing ointments or even by means of poul- tices. In feeding the animal, grind the oats and mix with warm water. I. For obstinate cases : Black antimony av.oz. I Sulfur av.oz. i Fennel seed av.oz. I Calamus root av.oz. I Juniper berries av.oz. 2 Rye flour av.oz. 2 Oil of turpentine fl.dr. iY 2 Water enough to make a mass. Give a mass the size of a duck's egg four times a day. II. Black antimony Ammonium chlorid Sulfur Juniper berries Sodium sulfate Rye flour . .av.oz. . . .av.oz . .av.oz. . .av.oz. . .av.oz. . .av.oz. 2Y 2 3 3 9 9 10 Water, to make a mass. Give a piece the size of a duck's egg every 2 hours. III. For very mild cases : Buckthorn berries, coarse powder av.oz. 2 Anise seed av.oz. 2 Sodium chlorid av.oz. 5 Sodium bicarbonate av.oz. 1 Strew 2 teaspoonfuls on each meal. IV. This is employed to promote the nasal secretion. Ammonium carbonate dr. 3 Oil of turpentine fl.dr. 3 Water fl.oz. 3 Put about 7 ounces of hayseed into a basin, pour hot water into it, and to this add the above ingredients; cover the horse's head with a cloth, and stir its contents thoroughly, so as to facilitate the liberation of the steam. Keep this up for a quarter of an hour. Repeat the treatment once each day. Gnat Oil. The following preparation is said to have been used successfully as an appli- cation to stock to guard against the at- tacks of "buffalo gnats": Crude carbolic acid... fl.oz. t Fish oil fl.oz. 15 See also Flies, Treatment for. Grease, Remedies for. By grease is understood an inflamma- tion of the heel accompanied by a fetid discharge. Treatment is only external, the affected feet being washed 2 or 3 times, daily with green soap and water and dried thoroughly, after which coun- ter-irritant or astringent remedies are to be applied, such as one of the following : I. Copper sulfate gr. 120 Ferrous sulfate gr. 120 Alum gr. 160 Water fl.oz. 16 Apply this lotion after washing and then wrap with a woolen bandage. II. Salicylic acid gr. 80 Carbolic acid rn. 40 Sweet oil A-oz. 8 Wash the parts three times daily with green soap and water, then dry with a cloth, and apply this oil. Gripes, Medicines for. See Colic Remedies. Heave Medicines. I. Linseed meal Sodium sulfate Elecampane Lobelia Rosin weed . .av.oz. . .av.oz. . .av.oz. . .av.oz. . . av.oz. 15 10 10 10 10 Alum . .av.oz. 5 5 3 1 Fenugreek Gentian Blood root Tartar emetic . . av.oz. . .av.oz. . .av.oz. . .av.oz. The dose is a tablespoon : ul 3 times day. II. Linseed meal Rosin weed Lobelia Elecampane Sodium sulfate . .av.oz, . .av.oz. . .av.oz. . .av.oz. . .av.oz. 15 10 10 10 10 610 THE STANDARD FORMULARY Heave Medicines (Cont'd). Fenugreek av.oz. 5 Alum av.oz. 5 Conium av.oz. 3 Bloodroot avoz. 3 Gentian av.oz. 3 Tartar emetic av.oz. 1 The dose is a tablespoonful 3 times a day. III. Tartar emetic av.oz. 1 Lobelia av.oz. 2 Skunk cabbage av.oz. 4 Elecampane av.oz. 4 Licorice root av.oz. 5 This may be diluted if desired with linseed meal, fenugreek, or other drugs. The dose is a teaspoonful 3 times a day. IV. The U. S. Bureau of Animal In- dustry states that arsenic is effective for palliating the symptoms. It may be given as Fowler's solution or solution of arsenous acid in doses of 1 fluidounce in the drinking water, or as powdered arsenous acid in 3-grain doses with the feed, each to be given 3 times a day. The dose may be cautiously increased as the animal becomes accustomed to the drug. If the bowels do not act regular- ly, a pint of raw linseed oil may be given once or twice a month, or a hand- ful of glauber's salt may be given in the feed twice daily, as long as may be nec- essary. However, all medical treatment is of secondary importance; most atten- tion should be paid to the diet. Heels, For Cracked. If there is much heat but the skin is unbroken, a lotion of 1 dram of lead acetate to a pint of water may be ap- plied on a thin bandage, covered in cold weather with a dry one. This same lo- tion may be used after the cracks ap- pear, or a mixture of equal parts of sul- furous acid, glycerin and water, applied on cotton and well covered by a band- age. In case these should prove unsuita- ble, the following may be used : Lead acetate, fine powder dr. 4 Carbolic acid drops 40 Petrolatum av.oz. 4 Herpes, Remedies for. Herpes consists of minute vesicles that appear in circular groups or clus- ters, with little tendency to burst but rather to dry up into thin scabs. It sometimes accompanies or follows speci- fic fevers, and is, on the whole, most frequent at the seasons of changing the coat — spring and autumn. It is seen on the lips and pastern but may occur on any part of the body. The duration of the eruption is two weeks or more, the tendency being to spontaneous recovery. The affected part is very irritable, the disease causing a sensitiveness and a disposition to rub out of proportion to the extent of the eruption. It may be treated with zinc ointment. The irritation may be allayed by apply- ing an aqueous mixture containing op- ium, belladonna, or lead acetate. A course of bitters, such as half an ounce of cinchona once daily for a week may strengthen the system and thereby coun- teract the disposition to the eruption. Hoofs, Preparation for the. Aside from the appearance which it gives a horse's hoofs, the occasional use of a good hoof-dressing really promotes the comfort of the animal and prevents brittleness of the hoof. The following are simple and useful formulas for this purpose : I. Oil of origanum fl.oz. 1 Camphor av.oz. 1 Lard av.oz. 16 Apply twice every week or two. II. Tar av.oz. 8 Tallow av.oz. 8 Use like the preceding. III. Should there be any disease of the hoof as hoof-bound, etc., the follow- ing ointment will produce sa'tisfactory results: Camphor av.oz. Balsam of fir av.oz. Oil of turpentine fl.oz. Oil of cajuput fl.dr. Compound tincture of iodin. fl.dr. Lard av.oz. 1 1 1 4 5 6 HORSE MEDICINES 611 IV. The following cement is useful for cracked hoofs : Gum turpentine av.oz. I Gum ammoniac av.oz. 3 Gutta percha av.oz. 6 The first two are melted together by means of a water bath, then added to the gutta percha, previously melted, with constant agitation. If a black color is desired lampblack may be added. When it is to be used the cement should be softened in hot water and pressed in the hoof crack, which has previously been well cleaned. Indigestion, Remedies for. See Dyspepsia and Indigestion, Rem- edies for. Influenza Remedies (Pinkeye — Epi- zooty). The early symptoms of this disease are languor and loss of appetite. After one or two days there is fever and an increased pulse-rate, the mucous mem- branes become yellowish, and the thirst increases while the appetite is diminish- ing. Internal and external remedies are used, the latter being usually ointments of a stimulant character. I. Sodium sulfate av.oz. 10 Licorice root av.oz. .7 Ammonium chlorid av.oz. 3 Potassium nitrate av.oz. 3 All should be in fine powder and be well mixed. Give 1 tablespoonful in warm soft food 3 times a day. II. Camphor, powder gr. 75 Poatssium nitrate dr. 5 Aloes av.oz. 1 Linseed meal av.oz. 1 Water, enough to make 2 boluses. Give I every 3 hours. III. This is used for the diarrhea which often manifests itself. Tannin gr. 8o Alum dr. 5 Licorice, powder , av.oz. 1 Simple syrup sufficient Make into 2 boluses. Give I every 5 hours. 39 IV. This is used as a purgative if one be required. Aloes dr. 5 Dried sodium sulfate av.oz. z l A Linseed meal av.oz. i l / 2 Soft (green) soap dr. 5 Simple syrup, enough to form a mass. Give in 2 doses with an interval of 2 hours. VI. This is for external use : Oil of turpentine fl.oz. 3 Spirit of camphor fl.oz. 17 Sprinkle upon the abdomen, rub with a brush of straw, and bind a warm blanket about the abdomen. VII. Chlorodyne fl.oz. 1 Spirit of nitrous ether fl.oz. 2 Solution of ammonium acetate fl.oz. 2 Water - fl.oz. 10 This dose is to be given every 3 hours during the first stage when there is much shivering. VII. The U. S. Bureau of Animal Industry recommends injecting large quantities of cold water into the rectum as the safest antipyretic. Antipyrine may be used with alcohol and strychnine. Quinine and salicylic acid may be given in i-dram doses, but the continuous use of quinine may increase the after-de- pression. Jaundice Remedies. Jaundice, or "the yellows," causes a yellow discoloration of the mucous mem- branes of the eyes, nose and mouth. The urine is saffron-colored, the dung is of a dirty gray color, and there is usually constipation. It is caused by the reten- tion and absorption of bile into the blood. It may be an accompaniment of any inflammatory disease. Treatment consists in ridding the sys- tem of the excess of bile and this is best accomplished by giving purgatives that act on the liver, such as calomel, 2 drams, aloes, 7 drams. Glauber's salt in handful doses once or twice a day for a week is also effective. Mandrake, rhu- barb, castor oil and other cathartics that. 612 THE STANDARD FORMULARY Jaundice Remedies (Cont'd). act upon the first or small bowels may- be selected. The bowels should be kept open by avoiding hard, dry, bulky foods. Laryngitis, Remedies for. The following remedy is highly rec- ommended : Cocaine hydrochlorid gr. 30 Codeine sulfate gr. 75 Bitter almond water fl.oz. 12 Give J / 2 to 1 ounce every 4 to 6 hours. Liniments. These preparations may be dispensed under such names as Horse Liniment, Veterinary Liniment, Barbed Wire Lini- ment, Stable Liniment, etc. I. Carbolic acid, crude fl.oz. 2 Benzine fl.oz. 15 Oil of turpentine fl.oz. 15 Oil of tar fl.dr. 4 Oil of spike fl.dr. 4 Camphor dr. 2 Capsicum dr. 2 Macerate for several days, then strain. II. Camphor av.oz. 1 Carbolic acid fl.oz. 1 Oil of origanum fl.oz. 2 Oil of tar fl.oz. 2 Crude petroleum fl.oz. 2 Oil of turpentine fl.oz. 12 Liquid petrolatum fl.oz. 12 Benzine fl.oz. 16 III. This is called White Oil Stock Liniment : Eggs 2 Green soap av.oz. 1 Gum camphor av.oz. 1 Ammonia water fl.oz. 1 Alcohol fl.oz. 1 Oil of origanum fl.oz. 1 Oil of turpentine fl.oz. 3 Water fl.oz. 3 Mix the soap and water to a smooth paste, beat in the eggs, add the oils and incorporate thoroughly. Dissolve the camphor in the alcohol and stir this into the previous mixture. IV. This is recommended as an espe- cially good "barb-wire liniment" : Carbolic acid fl.oz. */> Oil of turpentine fl.oz. 1 Pine tar fl.oz. 2 Fish oil, to make fl.oz. 16 Wash the cut or sore thoroughly with warm water and castile soap and apply the liniment once daily for a week. Then 2 or 3 times a week thereafter. Mange or Scabies Remedies. Scabies is most apt to affect old or ill-fed horses and generally appears on the side of the neck, on the shoulder, the back, the hips, at the root of the tail and on the feet. In all cases the first thing to be done is to wash the affected parts with a warm solution of green soap. The ani- mal must also be separated from the others, and special care taken in feeding and grooming it. It must be curried and brushed with implements not used on the other animals, and the harness must be reserved strictly for it to pre- vent infecting the other animals. Mange is always caused by a minute animal, called an acarus or mite. This animal burrows in the skin, a scab being formed, in which the mite may be dis- covered by the aid of a magnifying glass. The symptoms are, of course, an incessant and intolerable itching with the formation of scab, the size of the scab constantly increasing. I. Creosote, beechwood fl.oz. 2 Green soap av.oz. 10 Alcohol fl.oz. 6 Mix and apply to the affected parts after washing and drying them. II. Sulfurated potassa Green soap Water Oil of turpentine. . Dissolve the soap and the potassa in the water by the aid of heat, and then add the oil of turpentine. Wash the affected parts with a weak solution, dry with a cloth, and then ap- ply this liquid. Repeat this once a day. III. This is recommended for foot mange : Salicylic acid av.oz. ^2 Mercurial ointment av.oz. 3 Lard av.oz. 6 l / 2 av.oz. 1 av.oz. 2 fl.oz. 17 fl.dr. 2 HORSE MEDICINES 613 Wash the affected parts with a solu- tion of green soap, then dry them and apply this ointment once a day. IV. The U. S. Bureau of Animal In- dustry directs the removal of the scabs by soapsuds, and, if necessary, with a brush, and the thorough application of a decoction of tobacco leaves, 3 av. ounces to a half gallon. This may be applied more than once and should always be repeated after 15 days to destroy the new brood of acari that may have been hatched in the meantime. All harness and stable utensils should be similarly treated; blankets and rubbers may be boiled, and the stalls should be covered with a whitewash of lime containing 4 av. ounces of chlorinated lime to the gallon. V. Trasbot's (French) application is the following: Coal tar fl.oz. 3 Oil of cade fl.oz. 3 Benzine fl.oz. 10 VI. At the Veterinary School at Toulouse (France) the following is pre- ferred : Burnt alum av.oz. 2 Sulfur av.oz. 3 Sabadilla, powder av.oz. 5 Sweet oil pints 3 Digest on a water bath for 2 hours. Mosquito Oil. Carbolic acid, or cresol Oil of pennyroyal Spirit of camphor Oil of tar Lard oil This is effective for keeping flies and mosquitoes off horses. Ointments. Ointments are a class of very useful remedies for the treatment of some of the diseases of stock. Every pharmacist should have on hand, ready for sale, a good veterinary ointment. I. Compound tincture of iodin. fl.oz. 2 Camphor Oil of sassafras. . . . II. .fl.oz. .fl.oz. .fl.oz. .fl.oz. .fl.oz. . .av.oz. ...fl.oz. Lard av.oz. 15 Tannin av.oz. y 2 Carbolic acid, crystal av.oz. 1 Oil of origanum fl.oz. 1 Camphor av.oz. 3 Zinc oxid av.oz. 3 Lard av.oz. 16 III. Some of the ointments mention- ed under "Preparations for the Hoof" and "Remedies for Galls or Blisters," may also be recommended for general use. Peritonitis, Treatment for. The U. S. Department of Agriculture recommends opium, in powder, 1 or 2 drams, with calomel, 30 grains, every 2, 3 or 4 hours. Extensive counter-irri- tants are to be applied to the abdomen, consisting of mustard plasters, mercurial ointment, turpentine stupes, or even mild blisters. Purgation should never be re- sorted to. If it is desired to empty the bowels, do so with gentle enemas, but usually this is not necessary. Pinkeye, Remedies for. See Influenza Remedies. Poisoning of Horses. In cases where it is necessary to kill a horse and it is impossible to shoot him, as, for example, when he is in a stall, a German veterinarian recommends inject- ing a solution of strychnine (sulfate or nitrate) into the jugular vein. Quittor, Remedies for. Quittor is a term applied to various affections of the foot wherein the tis- sues which are involved undergo a proc- ess of degeneration that results in the formation of a slough followed by the elimination of the diseased structures by means of a more or less extensive sup- puration. The disease may attack the cutaneous tissues or it may strike deep- er. In any event, the parts must be kept clean and free from pus. The proper kind of application to make is one of antiseptic character. A solution of mer- curic chlorid, 1 in 500, with some am- monium chlorid, is excellent. Balls of oakum arc to be wet with this solution 614 THE STANDARD FORMULARY Quittor (Cont'd). and applied to the wound, being retained in place by means of a bandage. Other remedies are a i% solution of copper or zinc sulfate or zinc chlorid, 4% carbolic acid solution, 2% solution of silver ni- trate, or creolin, pure or diluted. The following is also recommended: Ointment of mercury nitrate av.oz. 1 Cottonseed oil fl.oz. 3 Mix together by aid of a gentle heat. Bickets, Bemedies for. Rickets is a disease which frequently affects colts. The following is useful : Prepared chalk av.oz. 8 Calcium phosphate av.oz. 8 Potassium bicarbonate av.oz. 4 Fennel av.oz. 4 Reduce all to powder and mix well. Give 1 tablespoonful with each feed- ing. Bingbone Cures. See Spavin and Ringbone Cures. Bingworm, Bemedies for. There are two kinds of ringworm, the circinate (tinea tonsurans) and the hon- eycomb (favus). In the circinate form the symptoms are the formation of a circular scurfy patch where the fungus has established itself, the hairs of the affected spot being erect, broken, or split up and dropping off. Later the spot first affected becomes bald and there is around it a circular row of hairs which are erect, bristly, broken and split. These in turn are shed and a new row outside passes through the same process, so that the extension is made in more or less circular outline. Treatment consists in applying tinc- ture of iodin twice a week for 2 weeks, first shaving or extracting the hairs of the affected part. Whitewash the stable and stall to destroy the germs, wash the brushes and harness with caustic soda solution and apply a solution of corro- sive sublimate, 1 dram to a quart of water, and treat the blankets and such covering with boiling water. The honeycomb ringworm forms close- ly aggregated, dry, yellowish crusts on the trunk, shoulders, flanks or thighs, and is accompanied by severe itching. Treatment is the same as for the preced- ing. Scratches, Bemedies for. See Heels, For Cracked. Scabies, Bemedies for. See Mange or Scabies Remedies. Screw-Worm, Bemedies for. Screw-worm and other flies deposit their eggs in sores and wet, filthy spots in the horse's skin and the grub which hatches out gives rise to serious trouble. The wet, dirty hair should be removed and the wounds kept clean and rendered antiseptic by a lotion of 2% carbolic acid water, or a mixture of 1 part of oil of tar in 20 ounces of sweet oil, or other antiseptic application. The grubs that are present should be picked off. Shoulder, For Lame. Spirit of soap fl.oz. 5 Spirit of camphor fl.oz. 5 Ammonia water fl.oz. 1 Apply several times daily. Or use any good, strong liniment. See Liniments. If the lameness be of a rheumatic character sodium salicylate should be given. The following is also advised in lame- ness of the shoulder of rheumatic origin : Veratrine gr. 9 Alcohol fl.oz. 1 About 2^2 fluidrams are to be injected once daily into the affected part. Sinews, For Strained. Inflammation of the sinews in the rear part of the leg between the knee and hoof may result from injury or may be due to rheumatism, influenza, etc. The affected animal must not be worked, but should be walked about slowly for a half an hour every day. If the affection is a recent one, apply one of the below mentioned lotions. If there is no im- provement in the course of a week, apply the salve of mercurial ointment with potassium iodid. HORSE MEDICINES 615 I. Ammonium chlorid dr. i l / 2 Spirit of camphor fl.dr. V/* Diluted acetic acid fl.oz. 4 Water fl.oz. 12 Mix and apply on a cloth morning and evening for at least 8 days. II. Spirit of camphor fl.oz. 2 Spirit of ether fl.oz. 2 Tincture of capsicum fl.oz. 3 Alcohol fl.oz. 4 Oil of turpentine fl.dr. i l / 2 Ammonia water fl.dr. 3 Ammonium chlorid av.oz. 1 Sodium chlorid dr. 3 Water fl.oz. 7 Dissolve the salts in the water and add the remaining ingredients. Shake the embrocation well. Dilute half a pint of the fluid with a pint and a half of water and with this wash the entire length of the leg and then wrap it up in a woolen bandage. Spavin and Ringbone Cures. As will be observed, these are usually of a counter-irritant or blistering char- acter. I. Oil of turpentine fl.oz. 8 Alcohol . fl.oz. 8 Tincture of iodin ...fl.oz. 8 Camphor av.oz. 4 Crude petroleum fl.oz. 1 Oil of rosemary fl.dr. 4 II. Oil of turpentine fl.oz. 13 Alcohol fl.oz. 13 Tincture of iodin fl.oz. 2 Camphor av.oz. 2 Oil of sassafras fl.oz. 2 Crude petroleum fl.oz. 1 Corrosive sublimate gr. 70 Dissolve the camphor and the cor- rosive sublimate in the alcohol and add the remaining ingredients. For ringbone cut off the hair and rub the ointment well into the lumps once in 48 hours. For spavins, apply once in 24 hours for three mornings. Wash well, previous to each application, with clean soapsuds, rubbing over the places with a smooth stick to remove the thick yellow matter. III. Tincture of cantharides fl.oz. 1 Tincture of iodin fl.oz. 3 Tincture of myrrh fl.oz. 3 Oil of turpentine fl.oz. 4 Alcohol fl.oz. 5 IV. Cantharides, powder av.oz. 4 Oil of origanum fl.oz. 4 Oil of amber fl.oz. 4 Oil of turpentine fl.oz. 4 Cotton seed oil '.. fl.oz. 4 Sulfuric acid fl.oz. 1 Mix all except the acid in a broad, shallow vessel such as an evaporating dish, then very slowlv and with constant and rapid stirring add the acid. When the liquid has cooled it may be bottled. For ringbone or spavin apply with a sponge tied to the end of a stick until it is no longer absorbed into the oarts ; 24 hours afterwards grease well with lard, and in 24' hours more wash off with clean, warm soapsuds. Two or thre^ applications 3 or 4 days apart may be required. Spavin, Foot, Remedies for. So-called foot spavin, if slight, may possibly be dispersed by means of hot poultices of linseed or bran. If the swelling is tolerably large, make an open- ing on the lower side to allow the fluid to escape, cleanse the cavity by injecting 2% carbolic acid water, and then apply a counter-irritant ointment, such as the following : Green soap av.oz. 4 Ammonia water fl.oz. 1 Crude petroleum fl.dr. 5 Tincture of cantharides fl.dr. 5 Rub daily for 1 or 2 days, then omit for 2 days and repeat the application. Continue this intermittent application until the ointment is all used. Staggers, Remedies for. Staggers are of two kinds, the first being known as "blind, sleepy or mad staggers," and called technically phre- nitis. It is an inflammation of the brain, in which the animal practically loses his senses, plunges in the stall till loose, and then dashes madly about, regardless of GIG THE STANDARD FORMULARY Staggers (Cont'd). all obstructions, striking or biting at anything in his way. It usually proves fatal, and if not the animal only par- tially recovers. The method of treatment formerly advised was copious bleeding, but this, even if successful in saving the animal, leaves him in such a weakened state that he is practically valueless. A better method of treatment is to give I or 2-dram doses of tincture of gelsem- ium every 4 hours, also a dose of 8 av. ounces of glauber's salt in thin bran mashes. The head should be bathed in cold water. The other kind of staggers is called "stomach staggers," and is due to disten- tion of the stomach from overfeeding, which results in cerebral symptoms man- ifested first by drowsiness and sleepi- ness, followed by a sudden awakening of the animal, when he throws himself about violently and his eyes take on a wild, unmeaning stare. This form of staggers, if not properly treated, may also prove fatal. The following treat- ment will prove effective : Fluid extract of ginger fl.oz. 6 Sodium hyposulfite av.oz. 2 Water fl.oz. 4 Dissolve the sodium salt in the water and add the fluid extract. The dose is a wineglass ful every 4 hours. A stimulat- ing injection of a handful of salt in 4 quarts of water should also be used. As soon as the medicine arouses the diges- tive functions and the food passes the pylorus into the intestines, the animal will obtain relief. Both food and water should be withheld until there is marked improvement. Stomach Catarrh, Remedies for. Gastric catarrh is frequently accom- panied by constipation or diarrhea. In either case, the appropriate remedy must be given. See under Constipation Cures or Diarrhea Remedies. I. For chronic cases : Sodium bicarbonate av.oz. 4 Sodium chlorid av.oz. 4 Sodium sulfate av.oz. 4 Juniper berries av.oz. 2 Reduce to coarse powder and mix well. Give 1 tablespoonful with each meal. II. For acute cases: Precipitated chalk av.oz. 3 Sodium chlorid av.oz. 3 Gentian av.oz. 1 Fennel av.oz. 1 Reduce all to powder and mix well. One tablespoonful is to be given with each meal. Strangles, Remedies for. Strangles, also called distemper and colt-ill, is an infectious disease, seen mostly in young animals, and usually leaving an animal which has had one at- tack protected from future attacks. It appears as a fever, lasting a few days, with the formation of matter or pus in the air tubes and lungs, and frequently the formation of abscesses in various parts of the body, both near the surface and in the internal organs. It usually leaves the animal after convalescence perfectly healthy and as good as it was before but sometimes leaves it a "roar- er," or is followed by the development of deep-seated abscesses, which mav prove fatal. Ordinary light cases require but little treatment beyond warm mashes, mois- tened hay, warm coverings, and protec- tion from exposure to cold. The latter is especially required, as lung complica- tions, severe bronchitis and laryngitis often result as a neglect of this precau- tion. If the fever is excessive the ani- mal may be given a handful of glauber's salt three times a day as a laxative, also sodium bicarbonate or nitrate in i-dram doses every few hours, and small doses of black antimony, potassium iodid, aco- nite or quinine. Steaming the head with vapors of warm water ooured over a bucket of bran and hay, in which bella- donna leaves and tar have been placed, will allay the inflammation of the mu- cous membranes and greatly ease the cough. The swelling of the glands should be promptly treated with hot linseed poul- HORSE MEDICINES 617 tices, and as soon as pus h?is formed the swelling should' be opened. Blisters and irritants should not be applied to the throat. When convalescence begins care should be taken not to expose the ani- mal to cold, which may bring on a re- lapse, and while exercise is of advan- tage, it must not be carried to excess un- til the animal has entirely regained its strength. Sunstroke, Treatment for. The term sunstroke is applied to affec- tions occasioned not exclusively by ex- posure to the sun's rays, but also by the action of great heat combined generally with humid atmosphere. Exhaustion produced by a long-continued heat is often the essential factor, and is called heat exhaustion. Horses on the race- track undergoing protracted and severe work in hot weather often succumb to heat exhaustion. Draft horses, which are exposed to the direct rays of the sun for many hours and do not receive prop- er care in watering, feeding and rest in shady places, suffer very frequently from sunstroke. Sunstroke is manifested suddenly. The animal stops, drops his head, begins to stagger and soon falls to the ground un- conscious. The breathing is marked with great stertor, the pulse is very slow and irregular, cold sweat breaks out in patches on the body, and the animal oft- en dies without recovering conscious- ness. The temperature rises very high, reaching 105 to 109 deg. F. In heat exhaustion the animal usually requires urging for some time previous to the appearance of any other symp- toms, generally perspiration is checked, and then he becomes weak in his gait, che breathing hurried or panting, the eyes watery or bloodshot, the pulse rapid or weak, followed by unconsciousness and death. If recovery takes place, con- valescence extends over a long period of time, during which there is lack of co- ordination of movements of the limbs. Blood-letting is absolutely not to be permitted in sunstroke. Ice or very cold water should be applied to the head and along the spine, and half an ounce of ammonium carbonate or 6 fluidounces of whiskey should be given in a pint of water. Cold water should be showered upon the body of the horse from a hose or otherwise. This should be continued until the temperature is down to 103 deg. F. Brisk friction of the limbs and the application of spirit of camphor often yield good results. The administration of the stimulants should be repeated in an hour if the pulse has not become slower and stronger. In either case, when reac- tion has occurred, preparations of iron and general tonics are to be given dur- ing convalescence. Iron sulfate dr. 1 Cinchona dr. 2 Gentian dr. 3 Give one such dose with the feed each morning and evening. Thoroughpin, Remedies for. This is an enlargement above the hock and is an inflammation of the synovial sac. Formerly the sac was lanced, but this is not now thought to be good treat- ment. A better plan is to puncture the sac by means of small needles and to empty the fluid through these holes. After this apply an ointment of iodin consisting of 1 dram of iodin to 7 drams simple ointment. Then apply a spring truss so constructed as to press on both sides of the hock. By this means the internal parts of the sac are kept in con- tact and they finally unite. The following application is also rec- ommended : Spirit of camphor rl.oz. 2 Ammonia water rl.oz. 2 Sweet oil rl.oz. 2 Oil of turpentine fl.o Tincture of arnica rl.oz. 4 Tincture of iodin rl.oz. 4 It should be applied at least twice daily. 618 THE STANDARD FORMULARY Thrush, Running, Remedies for. I. Chlorinated lime av.oz. \ l / 2 Water fl.oz. 16 First wash the affected parts with soapsuds, rinse with clear water, and then wash with the solution of chlorin- ated lime previously warmed. Then press some oakum, first moistened with the so- lution, into the opening. Repeat the ap- plication once daily. II. Alum av.oz. I Copper sulfate av.oz. I Carbolic acid "fl.dr. \ l / 2 Water ii.oz. 10 Use like the preceding. III. Zinc carbonate, Boric acid, Calomel, each, equal parts. Calomel alone is also an excellent dressing. Urinary Disease, Remedies for. Urinary diseases are usually manifest- ed by conditions known as polyuria, or the voiding of a large amount of pale urine, and anuria, or retention of urine. The former is usually caused by feeding with decomposed fodder. The latter may be due to "colds," or it may be an ac- companiment of other conditions, such as colic. I. For polyuria : Camphor, powder av.oz. Yi Ginger av.oz. V/2 Rye flour av.oz. 8 Water to form a mass Give one-eighth of this mass mornings and evenings. If the disease still lingers on the fifth day, the following is recom- mended: Camphor av.oz. ^2 Alum av.oz. 1 Dippel's oil fl.oz. 1 White oak bark av.oz. 1 Angelica root av.oz. 3 Rye flour av.oz. i}/£ Water sufficient Reduce all the solid drugs to powder, mix well and add enough water to form a soft mass or paste. Give a piece the size of a hen's egg 3 times daily spread upon the tongue. II. For anuria : Juniper berries, crushed av.oz. 5 Chamomile av.oz. 1 Make an infusion by pouring on 6 pints of hot water, allow to stand 15 minutes, and strain through cloth, ex- pressing the residue in the strainer. Administer one-third of this infusion and use the remainder as an enema. III. The urine may also become bloody, due usually to mechanical injury, such as sprains or fractures of the loins, or to stone in the bladder, kidney, etc. If the disease is due to mechanical in- jury, treatment should consist first in removing the cause whenever possible, and then in applying general and local styptics. Irritants in the food must be avoided and stones in the bladder or uretha removed. Then mucilagenous drinks should be given freely, such as slippery elm or linseed tea, and styptics, such as tincture of iron chlorid, 3 fluid- drams; lead acetate, 30 grains; tannic acid, 30 grains, or oil of turpentine, 1 fluidounce. IV. See also Bladder Inflammation and Diuretic Remedies. Worms, Treatment for. Poorly-fed animals are more subject to these parasites than well-fed animals. Treatment consists in giving worm med- icine and good food. I. Oil of tansy fl.dr. 4 Crude petroleum fl.dr. 4 Asafetida, powder av.oz. ^£ Aloes av.oz. 1 Rye flour av.oz. 2 Wormwood, powder av.oz. s l A Water to form a mass or paste Every 2 hours a piece of the size of a hen's egg is to be spread upon the tongue. II. Asafetida av.oz. 1 Ginger av.oz. 1 Tartar emetic .av.oz. 2 Fenugreek av.oz. 4 Mustard av.oz. 4 CATTLE MEDICINES. 619 Poplar bark av.oz. 5 Corn meal av.oz. 5 American wormseed av.oz. 8 Salt • av.oz. 8 Two tablespoonfuls are to be given each morning before feeding until four doses have been given. III. The U. S. Bureau of Animal In- dustry states that among the best worm medicines may be mentioned santonin, oil of turpentine, tartar emetic, creolin, infusion of tobacco and bitter tonics. To destroy tape-worms, areca nut, male fern and pumpkin seeds are the best. If a horse is passing the long, round worms, the plan of treatment is to give twice daily for 3 or 4* days a drench com- posed of oil of turpentine or creolin, I fluidounce, and raw linseed oil, 2 or 3 fluidounces, to be followed on the fourth day by a purge of 1 ounce of aloes. Or the treatment may consist of 2 drams of santonin with 1 or 2 drams of calomel. This dose should not be repeated, but should be followed in 6 hours by a quart of raw linseed oil. If pinworms are present (the ones that infest the large bowels), injections into the rectum of infusions of tobacco or quassia chips, 4 ounces to the gallon, once or twice daily for a few days, and followed by a purge are beneficial. DIVISION II— CATTLE MEDICINES. The doses in the following formulas, when not otherwise specified, are intend- ed for a full-grown animal, consequently when the medicines are to be adminis- tered to young, small or weak animals a corresponding reduction must be made in the size of the dose, while for unus- ually large and strong cattle the doses may be increased. For young cattle the following will serve as a general guide. Dose Required at Different Ages. At I year, 25% of the adult dose. At 2 years, 50*% of the adult dose. At 3 to 4 years, 75% of the adult dose. Administering Medicines. Medicines may be administered to cat- tle by the mouth, by injection into the rectum, vagina, udder, veins, trachea, or under the skin, by insufflation into the nostrils, or they may be applied exter- nally. When systemic effects are desired, they are administered by the mouth or subcu- taneously, or, very occasionally, by the rectum. The simplest way to give medicines by the mouth is to mix them with the food or water. This can be done when the medicine is in the form of a powder or liquid, if but a small quantity is to be given, or if it does not have a taste that is: disagreeable to the animal and is not so irritant as to injure the lining mem- branes of the mouth and throat. The usual method of administering bulky or unpalatable doses is to mix them with a liquid vehicle, such as water, milk, molasses or beer, and to give them from a bottle. In administering a drench of this kind the head of the animal should be elevated a little by an assist- ant. This is best accomplished by stand- ing on the left side of the animal's head and grasping the nose with the thumb and fingers of the right hand inserted in the nostrils, and with the left hand be- neath the chin; the head is still further elevated and supported. If the animal is unruly it may be tied in a stall or placed in a stanchion. The medicine can now be poured into the mouth by inserting the neck of the bottle between the lips on the right side. Care must be taken to avoid getting the bottle between the back teeth. The mouth of the bottle should be inserted as far as the middle of the tongue and the liquid poured slowly. If the cow coughs the head must be lowered at once to permit the liquid to escape from the larynx. If pouring of the medicine is continued while the ani- mal is coughing, some oi the drench may pass down the windpipe to the THE STANDARD FORMULARY lungs and cause a severe or even fatal pneumonia. The bottle used must be large and strong with a sloping neck, without any sharp corners. The amount of liquid to be given in a drench depends on the effect sought and upon the nature of the medicine. In im- paction of the stomach very large quan- tities of liquid may be given, as much as a gallon, or several gallons at a time. Usually, however, it is not customary or desirable to give more than from I to 2 quarts at a dose, and not more than a pint unless required by the irritant prop- erties of the medicine. Medicines that are soluble should be completely dissolved before they are given. Medicines that are insoluble should be finely powdered and be well shaken with the vehicle just before administra- tion. In the latter case a menstruum with considerable body, such as molasses, flaxseed tea, or milk, will help to hold solids or oils in suspension. Boluses are sometimes given to larger animals, but they are not so well adapted to the medication of cattle as of horses. Solution is much slower in the paunch of the cow than in the stomach of the horse, and if the cow is so sick as to have stopped ruminating, the bolus may become covered up and lost in the mass of material in the paunch and remain there for days without producing any effect. The large size or veterinary gelatine capsules are convenient for administer- ing boluses or even liquid medicines. Capsules and boluses are administered by being placed (previously moistened) on the tongue, well back in the mouth while the tongue is drawn forward and the mouth is held open by means of a block of wood placed between the back teeth. The bolus or capsule should be dropped, the tongue released, and the block removed as nearly simultaneously as possible, ^o that the backward move- ment of the tongue will carry the bolus or capsule into the throat and lead to its being swallowed. Care must be taken to avoid having the hand cut or crushed while introducing the bolus or capsule. Medicines are usually administered by the rectum for the purpose of controll- ing the bowels and for the treatment of local diseases. Sometimes, however, medicines that have a general effect are given in this way when it is not possible to give them through the mouth. Only drugs that are readily absorbed should be given per rectum for a general effect, and they should be in somewhat larger doses or used more frequently than when given by the mouth. Such stimulants as ether, alcohol or aromatic spirit of am- monia, diluted with four to six times their bulk of warm water, may be used in this way. Rectal injections, or enemata, are used in the treatment of constipation. If it is the purpose of the injection to soften hardened fecal masses, the water should be lukew T arm and it may have some soap dissolved in it. If it is the purpose of the injection to stimulate sluggish bow- els to contraction, the water may be cold. Actinomycosis, For. Actinomycosis, commonly called "lumpy jaw," or "big jaw," is caused by the "ray fungus," scientifically known as ac- tinomyces. It begins as a swelling or enlargement of the jawbone. It may af- fect either the upper or lower jawbone, or both sides at the same time. The swelling is painful under pressure and is attached to the bone and skin. Finally soft areas appear beneath the skin, which break, forming ulcers or the openings of fistulous tracts extending back into the bone and discharging a yellowish, sticky pus, which sometimes contains hard, yel- low granules or fragments of bone. The jaws become distorted, the teeth drop out, and the destructive process becomes greater and greater. From what has been stated it will readily be understood that early treat- ment is necessary. When there is an external opening on the surface of the CATTLE MEDICINES. 621 swelling, it should be injected with tinc- ture of iodin. When there is no exter- nal opening, the skin over the swelling should be painted with the same liquid. The treatment should be applied once daily and should be continued until it is apparent that the growth of the swell- ing has been checked. Internally potassium iodid should be given in doses of 2 or 3 drams daily, di- vided into 2 doses, and given morning and evening in a pint of warm water. This should be continued for 2 weeks, then stopped for 10 days, to be recontin- ued if found necessary. Appetite, Loss of, For. Unless the loss of appetite is the pre- cursor of more serious affection, it may be treated as a simple disturbance of di- gestion. Any of the mixtures mentioned under Condition Powders in the division of Horse Medicines are supposed to pro- duce an improvement in the appetite. I. Gentian, powder av.oz. 2 Sodium bicarbonate av.oz. 2 Sodium chlorid av.oz. 6 Sodium sulfate, dried av.oz. 8 Give 2 tablespoonfulb to a large ani- mal, 1 tablespoon ful to a small animal, once a day, stirred with some water to make a paste. If this be continued for 8 days, it is said to produce a wonderful improvement in the appetite. II. Gentian, powder av.oz. 1 Magnesium sulfate av.oz. 10 Mix with 1 quart of warm water and give at 1 dose. III. This is for calves : Sodium bicarbonate gr. 300 Rhubarb, powder gr. 75 Divide into 2 doses and give each in a cup of chamomile tea. Appetite, Depraved, Remedies. Cattle affected with this disease have a variable and capricious appetite in re- gard to their regular food, but are liable to lick and eat substances for which healthy cattle show no inclination. They frequently lick lime, coal, earth, gravel, and even the dung of other animals. The aim in such cases should be to im- prove the process of digestion and to supply the animal with a sufficiency of wholesome food. The following should also be given : Iron carbonate av.oz. 4 Gentian av.oz. 4 Fenugreek av.oz. 4 Sodium chlorid av.oz. 8 Finely ground bone ("bone flour") 16 Reduce all to fine powder and mix well. Give a heaping tablespoonful 3 times a day. In addition to this, 3 tablespoon- fuls of powdered charcoal may be mixed with the animal's food 3 times a day, and a piece of rock salt should be placed where the animal can lick it at will. Blisters. If a blister for cattle, use one of those mentioned under Blisters in the division on Horses. Bowels, Inflammation of. See Stomach and Bowels, Remedies for Inflammation of the. Bronchitis, Remedies for. Bronchitis is an inflammation of the mucous membrane of the bronchial tubes. When a primary disease it is generally the result of what is known as "catching cold." It may be secondary to or complicated with many of the dis- eases of the respiratory system. It may also be caused by breathing irritating gases, or by the introduction of foreign bodies into the bronchial tubes, which sometimes results from injudicious or careless drenching when the larynx is in a temporarily relaxed state. It may be acute or chronic, and is divided, accord- ing to the seat of the inflammation, into bronchitis proper when the large tubes are affected, and capillary bronchitis when the smaller tubes are affected. The animal should be placed in a light, well-ventilated box and kept warm with blankets. The bowels should be kept in a soft condition by means of THE STANDARD FORMULARY Bronchitis (Cont'd). enemas, etc., but avoiding violent purga- tives. The food should be light and nu- tritious. In the early stages of the disease give the following mixture 3 times daily: Fluid extract of belladonna .. n. dr. 2 Solution of ammonium acetate- fl.oz. 4 Mix when giving with a half pint of water. In the later stages of the disease use this twice daily : Ammonium carbonate dr. 3 Spirit of nitrous ether fl.oz. 1 Water, to make fl.oz. 3 Mix this also with a half pint of water before administering. At the same time give 1 grain of strychnine, preferably in the form of pills or tablets containing nearly this amount. In some cases the following is prefer- able to either of the above and may be given with a pint of linseed tea every 4 hours : Spirit of nitrous ether fl.oz. lYi Aromatic spirit of ammonia. fl.oz. 2 Gum camphor dr. 2 Bronchitis is liable to assume a chron- ic form if not properly treated in its early stages. Remedial. treatment is of little avail when the disease becomes chronic. Burns and Scalds, Treatment. For superficial burns, use carron oil (equal parts of lime water and linseed oil). This will exclude the atmosphere and protect the inflamed skin. The blis- ters should be opened to let the fluid es- cape, but the cuticle raised by the blister should be allowed to remain. When the burn is extensive and deep sloughing oc- curs, the parts should be treated like other deep wounds, by poulticing, astrin- gent washes, etc. When the system has sustained much shock, internal stimu- lants may be required, such as 4 fluid- ounces of whisky or 2 drams of am- monium carbonate, every hour until the animal rallies. When the pain is very great, hypodermic injections of 6 grains of morphine may be administered every 6 hours. Carbolic Composition. See under Horse Medicine. This will I be found equally valuable for cattle. Colic Remedies. Colic is usually the result of too great indulgence in indigestible food; if not properly attended to may cause death. As a rule, the animal is constipated, eats nothing, but drinks a great deal, groans, etc. If there is no movement of the bowels within 3 days, the affection is likely to prove fatal. Treatment consists in emptying the bowels by means of the w r ell-oiled hand, after which enemas are to be given every hour. Internally oleaginous cathartics are to be given, to be followed, when the bowels have had a movement, with stomachic remedies. I. For enema : Green soap av.oz. 4 Sodium chlorid av.oz. 4 Linseed oil, raw fl.oz. 8 Water fl.oz. 32 II. Cathartic drench : Magnesium sulfate av.oz. 8 Linseed oil fl.oz. 32 Chamomile infusion (1 to 20) . : fl.oz. 96 Give 1 quart every 4 hours, until all is given, or until the bowels act. If the bowels act before all is administered, the medicine is to be discontinued. III. Stomachic: Ginger dr. 2}/ 2 Mustard dr. 2 l / 2 Gentian dr. 2y 2 Reduce all to powder and mix well. Give 1 such powder in a pint of warm water when the bowels have acted and the colic has passed off. IV. The U. S. Bureau of Animal In- dustry directs walking the animal about for 10 minutes before administering any remedy, as this allows time for a por- tion of the contents of the stomach to pass into the bowel, and renders it safe to give medicine. In many cases the walking exercise and the evacuation of CATTLE MEDICINES. 623 the bowel result in a cure of the disor- der. If the pains still persist, give a mixture of i fluidounce each of ether and tincture of opium, shaken up with a pint of warm water, and repeat the dose in half an hour if the animal is not re- lieved. Condition Powders. The "condition powders" mentioned under Horse Medicines are equally suit- able for cattle. Constipation Remedies. Constipation may result from unsuita- ble food, but may also be the accom- paniment of other diseases. Treatment consists in giving purga- tives and enemas and in emptying the bowels by means of the hands, previous- ly w T ell oiled. I. Black antimony dr. 3 Argols (crude tartar) av.oz. % Aloes av.oz. 1 Sodium sulfate av.oz. 18 All should be in powder and should be well mixed. One-fourth of this mixture should be administered every 3 hours in warm chamomile tea or other suitable vehicle. II. This is for calves : Rochelle salt av.oz. 2 Aloes, powder gr. 150 Linseed meal gr. 150 Give this mixture at 1 dose in 8 fluid- ounces of warm water. III. For enema: Green soap av.oz. 2> l A Water fl.oz. 32 Give as an enema every hour until evacuation of the bowels ensues. IV. For subcutaneous use: Eserine sulfate gr. 2 l / 2 Distilled water m. 90 Mix and dissolve. This may be injected subcutaneously to produce an evacuation of the bowels. Dehorning of Cattle. The U. S. Bureau of Animal Industry states that a 2 or 3-days-old calf may be dehorned, or more properly speaking, the development of the horns may be prevented, by the use of a stick of caus- tic potash. The operation is performed as follows, and is uniformly successful if the calf is not more than 3 days old : The animal is gently laid over on its side, in which position it is easily held by an assistant, while the operator clips the hair off the little prominence on the frontal bone which marks the spot on the uppermost side of the head where the horn would be developed. Then dip the stick of caustic potash in water and carefully rub it over the spot just clip- ped for about 10 seconds. The calf is now to be turned over and the corre- sponding portion of the frontal bone on the other side is to be clipped and cau- terized in the same manner. By this time the side first treated is dry and should receive a second application of potash. Give the other side a second treatment of potash, and if the matrix of the horn has been located and the caustic has been properly applied no horns will ever make their appearance. Diarrhea, Remedies for. Diarrhea may arise from a "cold" or may be an accompaniment of other dis- orders. The remedies used are usually efficient, but it is also necessary to cause the ani- mal to perspire by rubbing and then to cover it warmly. It is also essential to put the sick animal in a warm and roomy stall, free from drafts. The food should be restricted to a lit- tle dry feed (good hay, etc.), no green food being permissible and in place of cold water, warm starchy or mucilagin- ous water should be given. I. Nutgall, powder av.oz. \ l / 2 Licorice root, powder av.oz. i l / 2 Give in 2 doses with an interval of 2 hours, mixing each dose with a pint of warm water. II. Opium, powder dr. 2J/2 Peppermint, powder av.oz. Y\ Linseed meal av.oz. 1 (524 THE STANDARD FORMULARY Diarrhea (Cont'd). Give one-half in the morning, the re- mainder in the evening, in i pint of warm water. III. The U. S. Bureau of Animal In- dustry states that when the disease de- pends on irritating properties of the food which has been supplied to the ani- mal, it is advisable to give a mild purga- tive such as a pint of castor or linseed oil. When the secretions of the bowels are irritating, an ounce of magnesium carbonate and half an ounce of tincture of opium should be shaken up in a quart of linseed tea and given to the animal 3 times a day until the stools present a normal appearance. When there is de- bility, want of appetite, no fever, but a continuance of the watery discharges from the bowels, then an astringent may be given, such as tannic acid, i av. ounce, powdered gentian, 2 av. ounces ; mix and divide into 12 powders. One powder is to be given 3 times daily until the stools present a normal appearance. Each pow- der may be mixed with 8 fluidounces of whisky or blackberry brandy and a pint of water. Diarrhea in Sucking Calves, For. Diarrhea in young calves is a rather common as well as serious complaint. It may be due to catching "cold" or it may be caused by a fault in the milk. Wrap up the animal warmly and ad- minister internal medicines as below and also use suppositories to avoid irritation of the bowels. I. Precipitated chalk av.oz. ^2 Alum, powder av.oz. l /> Rye flour av.oz. 24 Yolk of egg sufficient Make into 5 pills. Give 1 pill every 5 hours. II. Hydrochloric acid m. 80 Chamomile infusion (1 to 20) fl.oz. 4 In cases of abnormally acid stomach, give the above in 2 doses with an inter- val of 5 hours. III. Suppositories : Tannin gr. 15 Cocoa butter gr. 180 Mix and form into 4 suppositories; insert 1 morning and evening after a passage of the bowels, inserting it as far up as can be done with the oiled finger. Dysentery, Remedies for. Dysentery may arise from a "cold" or from eating damaged food. Spring and autumn are the times when the affection is most common, owing to sudden and rapid changes in temperature. This dis- order is due to inflammation of the gas- trointestinal tract, and results in fre- quent stools of an offensive odor, and is often accompanied by fever. At first the stools contain undigested food, later, clots of blood, and subsequently they may be almost entirely bloody in charac- ter. Treatment must be started early in the course of the disease, as otherwise it may prove fatal. Treatment consists in energetic fric- tion of the abdomen with turpentine oil and wrapping in warm blankets, this to be repeated every 2 hours. Internally give opium or astringents but always in combination with mucilaginous drinks and oil. To alleviate the painful strain- ing incident to the frequent defecation, it is advisable to use one of the below- mentioned enemas. I. Salicylic acid gr. 75 Alum, powder av.oz. 1 Linseed oil, raw fl.oz. 7 Infusion of ground linseed. fl.oz. 60 Give a pint of this mixture every 3 hours. II. Salicylic acid gr. 75 Alum dr. 6 Tannin dr. 6 Linseed oil, raw fl.oz. 7 Infusion of peppermint (1:10) fl.oz. 7 Give one-half at a dose and repeat in 3 hours. . III. For enema: Salicylic acid gr. 15 Yolk of egg gr. 30 CATTLE MEDICINES. 625 Linseed oil, raw fl.oz. 4 Water fl.oz. 4 Mix well. In using, warm the mixture and inject into the bowels every half hour until the straining at defecation ceases, or better, inject after each evacuation of the bow- els. Dysentery in Sucking Calves. Dysentery in sucking calves sets in soon after birth and usually proves fatal. The disorder is infectious and the ut- most cleanliness is required to guard against it. Treatment must be begun as early as possible if the animal is to be saved. The animal is to be wrapped up in woolen blankets, and given internal remedies and rectal suppositories to re- lieve the painful straining due to fre- quent defecation. I. Salicylic acid gr. 40 Tannic acid gr. 40 Infusion of chamomile (1:25) fl.oz. 8 Give half at a dose and the remainder in 4 hours. II. Tincture of opium fl.oz. 1 Tincture of nux vomica fl.dr. 1^2 Port wine • fl.oz. 6 Give a tablespoonful every 3 hours. III. For suppositories: Salicylic acid gr. 10 Extract of rhatany gr. 30 Cocoa butter av.oz. 1 Mix and make into 10 suppositories. After every evacuation of the bowels, wash the anus with lead water, and in- sert a suppository as far as possible into the rectum by means of the oiled finger. Eczema Remedies. Eczema is not so common among cat- tle as in horses and dogs', in which it is the most common of all skin diseases. It is occasionally observed under sys- tems of bad hygiene, filthiness, lousiness, overcrowding, overfeeding, excessively damp or too warm stables. It is found to develop now and then in cattle that are fed upon sour substances, distillery swills, house and garden garbage, etc. There is no one method of treatment which will always prove successful, no matter how early it is begun or how small an area is involved. Special at- tention should be given to the general health of the animal and its environ- ment. Feeding should be moderate in* quantity and not too stimulating in char- acter — green feed, bran mashes, ground oats, clean hay, and plenty of salt. If the animal has been fed too high, give an active purgative, epsom salt prefer- red, once a week if necessary, and half an ounce of potassium acetate or nitrate may be given in the feed twice a day. If the animal is in poor condition and de- bilitated, give a tablespoonful of the fol- lowing mixture in the feed twice a day : Ferrous sulfate, Gentian, Sulfur, Sassafras bark, each, equal parts. If the animal is lousy, the parasite must be destroyed before the animal can be cured. The external treatment must vary with the character of the lesions; no irritating applications should be made while the disease is in its acute vesicular, or pustular stage, and in the chronic stage, active stimulants must be used. Much washing is harmful, yet crusts and scales must be removed in order to obtain satisfactory results from external applications. Both objects can be ob- tained by judiciously combining the cur- ative agents with such agents as will at the same time cleanse the skin. In the vesicular stage, when the 'skin is feverish and the skin is peeling off, exposing the moist dermis, an applica- tion of boric acid solution, 1 ounce to a quart of water, will often relieve the smarting or itching, and also serves to check the exudation and dry the surface. If it fails to have the desired effect, use creolin, 1 ounce to a quart of water, as a wash. Either of these washes may be used several times a day until incrusta- tion is well established. Then use creo- lin, 1 ounce to a pint of sweet oil, or 6*2fi THE STANDARD FORMULARY Eczema (Cont'd). zinc salve, giving the affected surface a thorough application once a day. In chronic eczema, when there is a succession of scabs, or scales, or indo- lent sores, or fissures, ointment of am- moniated mercury, citrin ointment, or mercurial ointment, each diluted with an equal amount of petrolatum, may be ap- plied every second day, taking care so that the animal can not lick the parts. In some cases the following mixture will act beneficially : Oil of tar fl.oz. I Glycerin fl.oz. 2 Alcohol, to make fl.oz. 2> 2 Rub this in after cleansing the parts with warm water and soap. The internal administration of arsenic often gives excellent results in chronic eczema. It may be given in the form of Fowler's solution, i ounce twice a day in water after feeding. - An alkali internally may be of service. As such give 2 ounces of sodium bicar- bonate twice daily. Sulfur may also be tried in ounce doses twice daily. Eye, Inflammation of. Inflammation of the eye is usually of a catarrhal character caused by catching "cold." The eye first appears reddened, then tears begin to flow, and a mucous substance appears which has a tendency to stick the eyelids together. Treatment consists in washing with warm milk and applying this solution every hour : Solution of lead subacetate. .fl.dr. i]/ 2 Distilled water, to make fl.oz. 4 Fever Medicines. Fever is usually an accompaniment of various diseases, but in the absence of knowledge of what the disease is the fever should be treated directly by ad- ministering purgatives with saltpeter; cold water enemas may also be used. The following will prove useful : I. Potassium nitrate av.oz. y A Sodium sulfate av.oz. 8 Give one-half of the above in of warm bran water at night. II. quart Sodium salicylate . Magnesium sulfate ....av.oz. 1 . . . .av.oz. 10 Use like the preceding. Flies, Treatment for. The remedies mentioned under Horse Medicines are recommended for cattle. Foot-Rot, Remedies for. In the earlier stages of the disease, be- fore pus forms beneath the horn, a thor- ough cleansing and an application of a 5% carbolic acid solution, clean stabling and laxative food will usually remedy the evil. Solution of cresol U. S. P. is also an excellent application. It should be applied to the suppurating tissue be- tween the claws in undiluted state. Care must be taken to avoid contact of this liquid with the skin about the coronary band or heels. If deep sloughing has taken place the carbolic or cresol solu- tion should be used and a wad of oakum or cotton smeared with pine tar should be secured firmly in the cleft. Some- times warm poulticing with flaxseed meal or bran becomes necessary to re- lieve excessive fever and pain. If the pus burrows under the horn, its channel must be followed by paring away the horn until the bottom is reached. The after-treatment should be the same as that already recommended. The following ointment is also good : Oil of turpentine fl.oz. 1 Rosin av.oz. 1 Linseed oil, raw .fl.oz. 2 Lard av.oz. 4 Verdigris av.oz. 4 Melt the lard, oil and rosin together, rub the verdigris to a smooth mixture with the turpentine, and add to *he other mixture. Founder, Remedies for. Founder or laminitis does not usually occur in such a severe form in the cow as in the horse, but a mild form, denom- inated "foot soreness," is fairly common. It may be caused by overfeeding, over- CATTLE MEDICINES. 627 Keating, continued standing without ex- ercise on a stone or cement floor with- out sufficient bedding, or by driving long distances over rough or stony soil. The inflammation is usually relieved by applying cold packs to the feet, or standing the animal on a soft floor in a stream of running water. It may be well to give a full dose of epsom salt, i to iY 2 pounds, followed by l / 2 ounce doses of saltpeter 2 or 3 times a day. Hoven, Remedies For. See Tympanitis Remedies. Indigestion Remedies. Indigestion is generally produced by irregular feeding or indigestible food, without taking sufficient exercise, or from eating large quantities of non-nu- tritious food. The symptoms are irregular passage of feces of an offensive cdor, the mouth is slimy, the tongue is coated, the appe- tite is much diminished, and the animal chews its cud but little. The treatment consists in the adminis- tration of mild laxatives combined with bitter tonics, and of hydrochloric acid. During the illness the animal should be fed only with very easily digestible food. I. Black antimony dr. 5 Argols (crude tartar) av.oz. 1*4 Wormwood av.oz. 2 Sodium sulfate av.oz. 15 Give one-fourth of this every 4 hours in a quart of warm water. II. For obstinate cases : Hydrochloric acid fl.dr. 4 Linseed meal av.oz. 3 Water fl.oz. 32 Give one-half at night and the remain- der in the morning. III. For chronic cases : Black antimony av.oz. x / 2 Aloes av.oz. 1 Argols (crude tartar) av.oz. 1 Calamus av.oz. 2 Linseed meal av.oz. 3 One-third of this is a dose which is to be given every night and morning in a pint of warm water. 40 Indigestion in Young Calves. The treatment must vary with the cause. If there is any irritant matter in the bowels, give 1 or 2 ounces of castor oil with 20 drops of tincture of opium. If the sour eructations are marked, a tablespoonful of lime water or 2 drams of calcined magnesia may be given 2 or 3 times a day. If the disorder continues after the removal of the irritant, give 30 grains of pepsin with a teaspoonful of tincture of gentian at each meal time. Any return of constipation must be treated by injections of warm water and soap. Insect Bites and Stings. See following heading under Horse Medicines: Bee, Wasp and Hornet Stings; Flies, Treatment for; and Mos- quito Oil. Itching, Remedies for. Itching is not a disease, only a sensa- tion. It is an affection produced by slight irritation from without or by an internal cause acting upon the sensory nerves of the skin. Nothing character- istic is seen except the secondary lesions produced mechanically by scratching or rubbing. A common cause of itching is dirt on the skin, due to insufficient care. If the ceiling of the stable is open so that dust and straw may fall down, the skin is ir- ritated and itching may result. It also occurs in some forms of indigestion. It may be due to affections of the liver or kidneys when an increase of effete ma- terial has to be thrown off by the skin. Some irritating substances when eaten may be excreted by the skin and thus coming in direct contact with the sen- sory nerves produce itching. In another class of cases the itching may be due to an atrophy, contraction or hardening of the skin when the nerves become irri- tated by the pressure. The chief reliance in treating this symptom must be change of food, plen- ty of exercise, and in most cases the ad- ministration of a cathartic, 1 to V/2 f>?S THE STANDARD FORMULARY Itching (Cont'd). pounds of epsom salt mixed with a handful of salt, a tablespoonful of gin- ger or black pepper, and about 2 quarts of water. Afterwards a half ounce of sodium hyposulfite may be given twice a day for a week, mixed with the feed. For external application when the skin is abraded or thickened from rubbing, a solution of borax, 2 ounces to a quart of water, may be used. A solution of carbolic acid, a half-ounce to a quart of water, may give relief in some cases. Jaundice, Treatment for. Jaundice may emanate from the liver or may result from intestinal catarrh. As in the human subject, it is manifested by yellow discoloration of the mucous mem- brane of the mouth, of the white of the eye, etc. The urine becomes dark and the feces light colored; the appetite is diminished and the animal becomes emaciated. Treatment consists in giving calomel and sodium sulfate and applying coun- ter-irritant ointments in the region of the liver. If no benefit results from this treatment, then the sodium sulfate should be given with aloes, rhubarb and juniper berries. I. Sodium bicarbonate av.oz. 2 Juniper berries, crushed. . .av.oz. 2 Sodium sulfate av.oz. 10 Give half of this in the morning and other in the evening, each dose with a quart of water. II. Aloes av.oz. 2 Rhubarb av.oz. 2 Argols (crude tartar) av.oz. 4 Calamus av.oz. 4 Sodium sulfate av.oz. 4 Reduce all to powder and mix well. Give 1 heaping tablespoonful in a quart of infusion of juniper berries 3 times a day. Lice Exterminators. Lice are most apt to trouble young animals, only troubling old ones when they are very dirty. Green soap and to- bacco are the agents usually employed. I. Crude naphthalin av.oz. 2 Green soap av.oz. 10 Alcohol fl.oz. 10 Water fl.oz. 40 Heat the whole together until dis- solved and then stir until cold. Rub the places infested by lice thor- oughly with the above, and wash off the next day with warm soda solution. When the animal is again dry repeat this oper- ation twice. The lice generally die after the second application. II. Oil of tar fl.oz. 2 Sweet oil fl.oz. 10 Apply once or twice daily. Liniments. Any of the liniments mentioned under Horse Medicines are equally valuable for cattle. Lumpy Jaw, Remedies for. See Actinomycosis, For. Mange, Treatment for. Mange or scabies in cattle is like mange in other animals a contagious dis- ease caused by an acarus or mite. There are two kinds of these acari in cattle, the psoroptes and symbiotes. The for- mer are the ones which most frequently affect cattle. The U. S. Bureau of Ani- mal Industry advises dipping mangy cat- tle in dipping tanks in the same manner as sheep are dipped (see Scab, Treat- ment for, in Division III). The follow- ing dipping solution is recommended : Sulfur av.lb. 24 Unslaked lime av.lb. 12 Water .gal. 100 Both lime and sulfur should be weigh- ed, not guessed at. Slake the lime with enough water to form a paste, and into this sift the sulfur and mix well. Then add this mixture to 25 or 30 gallons of boiling water contained in a kettle or boiler and boil the mixture for 2 hours at least, frequently stirring the liquid and sediment. The boiling should be CATTLE MEDICINES. 629 continued until the sulfur disappears, or almost disappears from the surface of the liquid, when the latter will have a chocolate or liver color. Water must be added from time to time to replace that lost by evaporation. Finally add enough water to make about ioo gallons of li- quid. The liquid only should be used for dipping. During the dipping of the cattle if the liquid becomes filthy it should be chang- ed, regardless of the number of cattle dipped. It should never be used when more than 10 days old. The tempera- ture of the liquid when used for dipping should be from 102 to no deg. F. Milk Fever. See Parturition Fever. Milk Secretion, for Diminished. When diminished milk secretion is not due to age or to disease, the following mixtures will prove useful. They have been dispensed under such names as Cow Powder, Milk Powder, and Pulvis Vac- carum. I. Caraway • av.oz. 4 Calamus av.oz. 4 Sodium chlorid av.oz. 2 Sulfur av.oz. 1 Reduce all to powder and mix well. Give 2 heaping tablespoonfuls twice daily in 1 quart of warm beer. II. Anise av.oz. 2 Fennel av.oz. 2 Black antimony av.oz. 4 Sodium chlorid av.oz. 4 All should be in powder and well mixed. This mixture should be used like. the preceding. III. Capsicum dr. 1 Anise av.oz. 1 Caraway av.oz. 1 Potassium nitrate av.oz. 2 Magnesium sulfate av.oz. 10 Reduce to powder and mix well. This is to be used if the suppression of milk is due to indigestion. The food should be changed and 3 doses of this medicine should be given at intervals of 2 days. Give in a quart of ale or beer. Milk, For Rapid Curdling of. There are conditions of cows when the milk soon becomes curdled in spite of the utmost cleanliness. The follow- ing mixtures may remove the difficulty. Of course foods containing the least amount of acid should be given the ani- mal. I. Sodium bicarbonate av.oz. 3 Precipitated chalk av.oz. 4 Fennel av.oz. 6 Linseed meal av.oz. 8 All should be in powder and should be well mixed. Given one-half in 1 quart of warm water, administering the remainder the next day. Milk, Red and Blue, Remedies. Red Milk. Blood may escape with the milk when the udder has been injured by blows, or when it is congested or inflamed or when the circulation has been suddenly in- creased by richer or more abundant food. The milk frothing up and assum- ing a pink tinge is often the first sign of "red water" and it may result from eat- ing acrid, or irritant plants like the ra- nunculacae, resinous plants, etc. Depos- its of tubercle or tumors in the udder, or induration of the gland may be causes, irritation due to milking contributing to draw the blood. There may also be a reddish tinge or sediment in milk when madder or logwood has been eaten. If milk becomes red after it is drawn, this may be due to presence in it of the Mic- rococcus prodigiosus. See also Udder, Inflammation of. The treatment must vary with the cause. In congested glands give 1 pound of epsom salt and daily thereafter ^2 ounce of saltpeter with a dram of potas- sium chlorate, also bathe the bag with hot or cold water and rub with cam- phorated oil. If the food is too rich or too abundant it must be reduced. If the disorder is due to acrid plants these (!30 THE STANDARD FORMULARY Milk Diseases (Cont'd). must be removed from the pasture or fodder. If there is induration of the udder, this may be overcome by rubbing with a mixture of iodin ointment i part, green soap, 2 parts, or a mixture of mercurial ointment and green soap may be used. Of course, care should be ex- ercised in milking. Blue Milk. Watery milk is always bluish, but the presence of the germ Bacillus cyanogens causes a distinct blue shade even in rich milk and cream. It may reach the milk- after it has been drawn, or it may find its way into the opening of the milk ducts and enter the milk as it is drawn. In the latter case, frequent milking and the injection into the teats of a solution of 60 grams of sodium hyposulfite in 8 fluidounces of water will serve to de- stroy them. If the milk is bluish simply because it is watery, the following remedy should be administered: Caraway seed av.oz. 1 Gentian av.oz. 1 Calamus av.oz. 1 Sodium chlorid av.oz. 4 Reduce all to powder and mix well. Give a tablespoonful with each meal. Mosquito Oil. See same heading under Horse Medi- cines. This preparation is also useful for cattle. Ointments. The ointments mentioned under Horse Medicines are also suitable for cattle. Parturition Fever (Milk Fever). Parturition fever usually occurs sev- eral days after calving. The animal re- fuses to eat food, is very restless, trem- bles violently, and then lies down with- out being able to get up again. Sub- sequently the animal lies on its side, gnashes its teeth, etc. The symptoms follow each other rapidly, and if the ani- mal is not treated so as to be on the road to recovery in 5 days, the disease will prove fatal. The animal must be kept in a warm stall, free from drafts, having a thick, high bed of dry straw. It should be kept covered with woolen blankets. Give saline purgatives and in- ject cool enemas with soap water. If the bowels have operated, give carmina- tives containing ether. Rub the small of the back with counter-irritant ointments. For the fever, give salicylic acid which may be added to the purgative as well as to the carminative. When the animal begins to eat again, give it warm, soft foods (bran mashes with linseed meal, etc.). The udder should be carefully emptied every hour during the course of the disease. I. Purgative : Camphor dr. 5 Salicylic acid av.oz. 1% Sodium sulfate av.oz. 14 Mix well and divide into 4 powders. Give 1 powder every 4 hours in a pint of warm chamomile tea. If purgation ensues before all the powders are given, the latter are to be discontinued. II. For the fever : Valerian root, cut av.oz. 4 Sodium salicylate av.oz. 1 Spirit of ether fl.dr. 5 Water pints 5 Pour 5 pints of boiling water on the valerian, let stand for x / 2 hour, then strain, adding warm water through the strainer to make the liquid measure 5 pints. To the colature add the other in- gredients. Give 1 pint of this mixture every hour. Rheumatism Remedies. In most cases, rheumatism is the re- sult of catching "cold/' It may be ac- companied with fever or there may be none. The febrile form usually lasts 8 to 10 days, the other may persist for several weeks. The treatment for the first kind consists in first bleeding a vein, then giving purgatives containing salt- peter. The second kind requires diuretic and purgative treatment. I. Ammonium chlorid av.oz. 2 Potassium nitrate av.oz. 2 Sodium sulfate av.oz. 12 CATTLE MEDICINES. 631 Reduce to powder, mix, and divide into 4 portions. This is used as a purgative, I powder being given every 3 hours in a quart of warm water. II. When there is fever, sodium salicylate in about i-ounce doses may be adminis- tered every 3 hours in a pint of warm water. It is not well to continue this treatment indefinitely on account of the danger of weakening the heart. The drug may be given continuously for a day as directed, after which 1 or 2 doses only per day should be given. III. When there is no fever the following may be recommended: Arnica flowers av.oz. 3J/2 Juniper berries, crushed av.oz. 2> l / 2 Ammonium chlorid av.oz. 1 Aloes av.oz. 1 Water, boiling pints 7 Pour the water upon the arnica and juniper, let stand X A hour, strain, and in the colature dissolve the remaining in- gredients. Warm I quart of this mixture and give every 5 hours. IV. Application : Oil of turpentine fl.dr. 6 Spirit of camphor fl.oz. yy 2 This mixture should be applied to the swollen joints every 6 hours. Rickets of Calves. This is caused by improper feeding, together with a "cold." The joints of the legs become swollen, feverish and painful, the animals suckle less and less, finally get cramps, and then die. A pre- ventive of this disease is to mix some bone ash daily with the mother cow's feed, and it is also advisable to admin- ister about 80 grains once daily to the calf. If the disease is advanced, rub the joints with alcoholic liniments, and give bone ash or oyster shell in milk; if there is diarrhea treat it by the usual methods. See Diarrhea in Sucking Calves, For. I. This powder is to be given to build up the bony system : Levigated oyster shell av.oz. 4 Give as much as will lie on the point of a small knife 3 times daily in milk. II. For diarrhea: Opium gr. 8 Magnesium carbonate gr. 40 Give this powder in 4 fluidounces of warm chamomile tea. III. If there is constipation, give 2 fluidounces of castor oil every 3 hours in warm milk. IV. For application : Spirit of camphor fl.oz. 2 Spirit of formic acid fl.oz. 2 Oil of rosemary drops 24 Rub the swollen joints several times daily. Any other alcoholic preparation may be used, such as spirit of camphor alone or soap liniment. Ringworm Remedies. See Tetter or Ringworm Remedies. Scabies, Treatment for. See Mange, Treatment for. Scalds, Treatment for. See Burns and Scalds, Treatment for. Shoulder Lameness, Treatment. Shoulder lameness may be caused by a misstep, bruise, or a fall, or it may be due to a "cold," in which case it is of rheumatic character. Treatment should consist in applying mild counter-irritants and in keeping the part warm. Ammonia water fl.oz. 3 Oil of turpentine fl.oz. 3 Spirit of camphor fl.oz. 6 Spirit of soap fl.oz. 6 Rub well into the lame shoulder 3 times daily. Southern Cattle Fever, For. See Texas Fever, Remedies for. Stomach Catarrh. See Indigestion Remedies. Stomach and Bowels, Inflammation of the. It is generally presumed that inflam- mation of the stomach and bowels is the result either of a "cold" or of eating- some poisonous weed. 632 THE STANDARD FORMULARY Stomach, Inflammation (Cont'd). The affection is manifested by loss of both appetite and thirst, restlessness, swollen abdomen, constipation, etc. Warm mashes should be given as food and warm linseed meal water be given in place of cold water to drink. Purga- tives containing oil should be given, also enemas, and the belly should be rubbed with stimulant applications. The animal should also be bled. The following may also be adminis- tered : I. Salicylic acid gr. 90 Infusion of chamomile (1 in 10) fl.oz. 32 Sodium sulfate av.oz. 10 Linseed oil fl.oz. 26 Administer 1 pint every hour until constipation is overcome. II. As an enema, mix i l / 2 ounces of salt and 3 fluidounces of raw linseed oil with a quart of soap water and inject every 3 hours until the bowels are re- lieved. III. Application : Linseed oil, raw fl.oz. 4 Ammonia water fl.oz. 4 Oil of turpentine fl.oz. 4 Rub the abdomen with this every 3 hours. Tetter or Ringworm. Tetter usually attacks old, underfed animals where stalls are poorly venti- lated and unclean. The stalls must first of all be thor- oughly cleaned, aired and whitewashed with lime, and the affected parts of the animal treated with the following : Green soap av.o" 10 Water fl.oz. 10 Pine tar av.oz. 5 Heat in a water bath until of a uni- form consistency. Wash the entire body of the animal every 2 days with warm green soap solu- tion (1 to 20), rinse with warm water and when the animal is dry rub the above ointment well in under the hair. The U. S. Bureau of Animal Industry directs this treatment : Remove all crusts by washing with soap and water, then apply acetic acid, sulfur ointment, tinc- ture of iodin or citrin ointment once a day. Cleanse the stable and whitewash it to destroy the spores scattered by the crusts. Texas or Tick Fever. When the disease has broken out, all animals, the sick as well as the healthy, should at once be removed to another non-infected pasture. While this may not cut short the disease, it may save the lives of some animals by removing them from the possibility of being attacked by more young ticks. Removal from in- fected pastures likewise prevents a sec- ond later attack in October or early in November, which is caused by another generation of ticks. It is true that sick native animals infect with a new gener- ation of ticks the pasture to which they are removed, but these usually appear so late that they have but little chance to do any damage. Medical treatment of the sick has gen- erally been unsatisfactory except in chronic cases and those occurring late in the fall. . If the animal is constipated, a drench consisting of 1 pound of epsom salt in a quart of water may be admin- istered, followed by 30 to 90-grain doses of quinine sulfate, according to the size of the animal, 4 times a day, until the system is well saturated with it. Tinc- ture of digitalis, 4 fluidrams, and whis- key or alcohol, 2 fluidounces, may be combined with the quinine, according to indications of individual cases. The fol- lowing tonic should be used in the con- valescent stage when the fever has run its course : Reduced iron av.oz. 2 Nux vomica av.oz. 2 Rhubarb av.oz. 2 Gentian av.oz. 2 Potassium nitrate av.oz. 6 Reduce all to powder and mix well. Give a heaping tablespoon ful in the feed 3 times a day. CATTLE MEDICINES. 633 The animal should be given a nutri- tious laxative diet with plenty of clean and cool drinking water. Experiments have been made by the U. S. Bureau of Animal Industry with regard to freeing cattle from ticks. When the herd is small, a very effective but laborious method is to pick off these parasites by hand or to scrape them off with a dull knife or currycomb. This should be done at least three times a week in order to find all the adults be- fore they mature and drop off. After removing the ticks, they should be de- stroyed, preferably by burning. Greasing the legs and sides of cattle with cotton-seed oil, fish oil or crude petroleum will assist in preventing the ticks from crawling up on the body. In small herds, smearing the cattle with a mixture of I gallon of cotton-seed oil, i gallon of kerosene and i pound of sul- fur, or with a mixture of equal parts of cotton-seed oil and crude petroleum has proved efficacious when applied to the skin 2 or 3 times a week during the tick season. Throat, Inflamamtion of. Inflammation of the throat usually re- sults from a "cold." The affected ani- mal does not swallow readily, liquids flowing out again through the nostrils, it coughs a great deal, and respiration is short and labored. The affection usually lasts 6 to 8 days. Treatment consists in making stimulating applications, such as liniments or baths or ointments. I. Ammonia liniment fl.oz. 8 Oil of turpentine fl.oz. 8 Rub the throat 3 times daily with this mixture and then bind with flannel. II. Alum dr. 6 Salicylic acid gr. 24 Honey av.oz. 1 Diluted acetic acid fl.oz. 2 Water fl.oz. 30 Mix and dissolve. Warm the solution and inject into the mouth every half hour. Or a linen cloth moistened with this solution may be employed to wash out the mouth. Thrush in Calves. It will be observed that the calf is dis- inclined to suckle its mother's teats. Upon examination of the mouth, the canker spots will be noticed. Treatment consists in washing out the mouth every 2 hours with fresh water, then applying the below mentioned lotion and giving the powder. I. Alum dr. 2^ Honey dr. 6 Infusion of sage (1:10) fl.oz. 7^ Mix and dissolve. Wash the mouth thoroughly every 2 hours with fresh water, then apply this solution. II. Rhubarb dr. 3 Prepared chalk av.oz. 1 Mix and divide into 3 powders. Give 1 powder every morning in some milk. Tympanitis Remedies. Tympanitis is the sudden production of a large amount of gas in the first stomach of the cow, which causes enor- mous distention of the abdomen, owing to failure of the gas to be discharged by the mouth or anus. It appears most fre- quently in animals which have just been turned out to green pasture in conse- quence of which they eat too greedily and hastily. The disorder comes on rap- idly and if not quickly relieved may prove fatal. If the gas has accumulated within the course of half an hour the speediest and surest way to gain relief is to puncture the rumen with a trochar. Evacuation of gas through the oeso- phagus is accomplished by pulling the tongue out of the mouth or by traction upon the commissures of the lips by means of a knotted straw rope; this gives rise to involuntary movements of the tongue which produce eructations and sometimes vomiting. The rectum should be emptied by means of the oiled f>34 THE STANDARD FORMULARY Tympanitis (Cont'd). hand, after which enemas of soap water should be injected and one of the fol- lowing drenches administered : I. Potassium sulfid av.oz. 2 Rye flour av.oz. 2 Lime water pints 4 Give 1 pint at a dose every y 2 half. II. Ammonia water fl.oz. V/2 Rye flour av.oz. 2 Lime water pints 3 Use like the preceding. III. Aromatic spirit of ammonia fl.oz. 2 Tincture of capsicum fl.dr. 2 Tincture of ginger fl.oz. 1 Water fl.oz. 16 Give at 1 dose. This may be repeated in half an hour if no relief is obtained, and if failing to relieve in another half hour, resort should be had to the tro- char. IV. Tympanitis may become chronic so that the animal bloats up after each feeding but not enough to cause alarm. Treatment should be commenced by giv- ing this cathartic mixture: Epsom or glauber's salt av.lb. 1 Ginger, powder av.oz. 1 Barbadoes aloes av.oz. l /z Molasses pint 1 . Water, lukewarm quarts 2 Mix the solids with the water and add the molasses. After purgation, the following tonic and antacid should be given to promote digestion : Gentian av.oz. 3 Potassium bicarbonate av.oz. 3 Ginger av.oz. 3 Capsicum av.oz. 1 Reduce all to powder, mix well and divide into 12 powders. Give 1 powder 3 times a day before feeding, mixed with a half pint of whis- key and a pint of water. It is also of advantage in such cases to give two heaping teaspoonfuls of wood charcoal, mixed with the animal's food, 3 times a day. If the dung is hard, the constipa- tion should be overcome by feeding a little flaxseed twice daily or giving a handful of glauber's salt in the feed once or twice a day. Roots, silage and other succulent foods should also be given. Udder, Inflammation of. Inflamed udder may result from in- jury or from cold, or as a result of other diseases. In the first stages, the milk appears normal, subsequently be- coming thick and even purulent or bloody. Treatment consists in gently evacuat- ing the udder mornings and evenings, and limiting the animal to half rations, which should consist of easily digestible food. The udder should be bathed in warm water after milking, and after drying an antiseptic application should be made. If the udder is hot and fever- ish, the application should contain mer- curial ointment. Saline purgatives should be administered internally. I. This is for use in the early stages : Salicylic acid dr. 1 Camphorated oil fl.oz. 4 Rub the udder carefully twice daily. II. To use when the udder is fever- ish : Salicylic acid gr. 40 Mercurial ointment av.oz. 1 Camphorated oil fl.oz. 3 Apply like the preceding. Urine Bloody. This is generally brought about by eating sour food or such as contain oxa- lates, either fresh or dried, which is generally the cause to be looked for. Treatment consists in changing the food. If the disease has been contracted while grazing, change to hay, or if it has been contracted from hay, place the animal at pasture or give it green food. If the change of food alone proves in- sufficient then use the following: Lead carbonate gr. 45 Sodium acetate dr. 2 l /x Camphor, powder dr. 4 Precipitated chalk av.oz. 4 Mix and divide into 6 powders. CATTLE MEDICINES. 635 Give i powder in a quart of bran mash morning and evening. The U. S. Bureau of Animal Industry states that treatment must vary accord- ing to the cause. If due to an irritant, a saline purgative, say i to i^ pounds of glauber's salt, will clear the irritants from the bowels and allay the fever. It will also serve to divert to the bowels much of the irritant products already ab- sorbed into the blood and will thus pro- tect the kidneys. In many such cases a liberal supply of wholesome, easily di- gestible food will be all the additional treatment required. Demulcent food, such as boiled flaxseed or wheat bran, is especially good. If much blood has been lost, bitters and iron, such as gentian, 4 drams, ferrous sulfate, 2 drams, should be given every day for a week. For cases in which excess of diuretic plants have been taken, the "salts" should be replaced by a pint or two of olive oil, adding 1 ounce of tincture of opium and 2 drams of gum camphor. In cases due to sprained or fractured loins, to in- flamed kidneys, or to stone or gravel, the treatment will be as far as possible for the particular ailment. Worm Remedies. Worms are readily produced by in- sufficient feeding, and are expelled by purgative worm medicines. It is impor- tant to give the animal but little food on the day previous, and to administer the worm medicine and the purgative at the same time. Wormwood, powder Tansy, powder Aloes, powder Dippel's oil Linseed oil, raw . . . Give in 2 doses, with an interval of 5 hours. The U. S. Bureau of Animal Industry recommends as treatment for the twist- ed wireworm a drench of a 1% solution of coal-tar creosote in water, of which 1 dose will usually be sufficient, or gaso- line of whieh 4 to 6 doses will be re- quired. The doses will vary according to the age of the animal, of the creosote av.oz. 1 av.oz. 1 av.oz. 1 fl.dr. 4 fl.oz. 16 solution from 8 ounces to a quart, of the gasoline, y 2 to i l / 2 fluidounces. For the encysted stomach worm there appears to be no successful treatment. Tape worms are frequent in cattle, but they appear to do no particular harm. If in addition to the twisted wire worms, the animals are suffering from a severe infection of bowel worms, such as hookworms, to each dose of creosote solution should be added 30 to 80 grains, or even 100 grains, of thymol. The above remedies, creosote solution and gasoline, are equally suitable for sheep, but using smaller doses. Wounds, Treatment of. Animals may be wounded in various ways, as by barb-wire fences, by blows, by being gored by other animals, etc. If the wound is large and open it must be sewed up. After-treatment of the wound is of great importance. Formulas are given in this Division under Ointments and Liniments for preparations that may be used as dressings or applications. The first treatment of every wound is a thorough cleansing. This may be ac- complished by allowing water containing 2% of carbolic acid to flow over it and picking out all foreign matter, dirt, straw, oats, etc. When the wound and adjacent parts are cleansed, dress with "white lotion" (Lotio Alba — see formula in Part I), or with a solution of 1 ounce of zinc chlorid to a quart of wa- ter. In cold weather the parts may be dressed with zinc salve. In superficial excoriated wounds, a good dressing after the cleansing is iodo- form in dry powder. This should be followed by a second dressing of pow- dered aloes, which not only forms an artificial scab but also keeps flies away, an important consideration in the treat- ment of wounds on animals. There are several other applications which are efficacious, such as 1 in 800 corrosive sublimate solution, saturated solution of boracic acid, or 3% carbolic acid solution. 636 THE STANDARD FORMULARY DIVISION III.— SHEEP MEDICINES. Most of the remedies described under the preceding two sections are equally well adapted for sheep, providing they be full-grown animals. Lambs frequent- ly require somewhat different treatment. Anemia Remedies. Anemia may be cured if the animal is promptly treated in the early stages of the disease. Good feeding and care is as essential as medicine. The animal should be kept in a w r arm stall except in pleasant days when it may go out to pas- ture. It should receive the best of food and drink, and also be given one of the following : I. Juniper berries, crushed av.lb. 2 Sodium chlorid av.lb. 2 Ferrous sulfate av.oz. 1 This is to be mixed with 12 gallons of the animal's mashes, and the dose is to be repeated once a week for at least 12 weeks. II. Juniper berries, crushed. .. .av.lb. 2 Calamus, powder av.lb. 2 Sodium chlorid av.lb. 2 To be mixed with the animal's fodder once a week. Colic Remedies. Colic may result from exposure to cold, from constipation, from overfeed- ing, or from worms. It is generally ac- companied by retention of urine and us- ually by constipation. If the ailment is due to cold, warming or stimulant remedies should be given, if due to overfeeding or constipation, give a purgative. In either case, keep the animal warm, make stimulant appli- cations, and give an enema. I. This mixture is useful in the treat- ment of colic resulting from cold. Capsicum gr. 30 Ginger gr. 120 Peppermint gr. 150 Linseed meal gr. 150 Sodium sulfate av.oz. 2 Reduce all to powder, mix well, and divide into four portions. Give 1 powder every hour in a cupful of warm coffee or warm beer. II. This preparation is advised when the colic is the result of overfeeding. Castile soap dr. 1 Fennel dr. 2 Linseed meal dr. 2 Chamomile dr. 2 Sodium sulfate av.oz. 3 Reduce all to powder, mix well, and divide into four portions. Every 2 hours, mix one powder with a cupful of warm water, add a table- spoonful of linseed oil, and give the mixture to the animal. III. For enema. Castile soap gr. 75 Sodium chlorid av.oz. i x / 2 Mix and divide into 5 powders. One powder is to be mixed with 8 fluidounces of infusion of chamomile and used as an enema, which is to be repeated every hour. Constipation Remedies. Constipation of sheep may result from difficultly digestible food, and may also result from a sudden change of food. Treatment consists in giving sodium sulfate internally as well as enemas. I. Caraway gr. 150 Sodium bicarbonate gr. 150 Linseed meal gr. 300 Sodium sulfate av.oz. 2]/ 2 Mix all in powder form and divide into three portions. Stir one into 8 fluidounces of warm water, add about one-half cupful of lin- seed oil, and give at one dose; repeat every 3 hours. II. Castile soap, powder gr. 75 Rye flour av.oz. V/ 2 Mix and divide into five portions. Stir one powder in 8 fluidounces of warm water and give as an enema every hour, SHEEP MEDICINES. 637 Diabetes, Treatment for. Diabetes usually affects whole flocks of sheep. It is caused by exposure to prolonged cold and damp weather, also by eating some kinds of leaves and twigs. Treatment consists in keeping the animals in warm stalls and giving one of the following remedies. I. Camphor av.oz. 2 Aloes av.oz. 2 Rye flour av.oz. 1 Linseed oil, raw fl.dr. 4 Make into a soft paste or electuary by suitable means. Give to each affected animal, a piece about the size of a hazel- nut, smearing it on the tongue. Repeat the dose every day until a cure is affected. II. Alum av.oz. 6 Iron sulfate av.oz. 6 This is to be dissolved in the ani- mals' drink. This amount is to be used with 15 gallons of water. Diarrhea Remedies. This affects old as well as young ani- mals and is dangerous when long-con- tinued. It may be caused by exposure to cold or by change from dry to green fodder, or by feeding partially decom- posed fodder. I. This is best adapted to older ani- mals. Ginger dr. 2 Wormwood dr. 2 White or red oak bark av.oz. 1 Juniper berries av.oz. x /i Sodium chlorid av.oz. 5 All should be in powder and be well mixed. One tablespoonful should be given 3 times daily in food. II. This is best adapated to lambs : Tannic acid gt*. 45 Rhubarb av.oz. 1 Prepared chalk av.oz. 1 Rye flour av.oz. 1 Calamus aV.oz. 3 All should be in powder, be well mix- ed, and be converted into an electuary by the addition of mucilage or syrup. A piece the size of a hazelnut should be given mornings and evenings. Eye Inflammation. Inflammation of the eyes in both lambs and sheep may be of catarrhal- rheumatic character or be due to me- chanical injury. The eye should be pro- tected from drafts and should be bathed twice daily with water after which one of the liquids mentioned below should be used. It is also advisable to admin- ister a mild cathartic. I. Tincture of opium drops 10 Lead water fl.oz. 2 Bathe the eye twice daily. II. Zinc sulfate gr. 5 Mucilage of quince seed fl.oz. 1 Distilled water fl.oz. 1 Mix and dissolve. Use like the preceding. Foot Rot, Treatment for. Foot rot in sheep is very common. In treating it the dead loosened portions of the hoof should be pared away with a sharp knife, and all dirt should be care- fully removed before making any appli- cations. A mixture of equal parts of solution of antimony chlorid and tincture of myrrh is recommended as a daily dress- ing; also a solution of 1 av. ounce each of alum and iron sulfate in a pint of water. Dip tow in this liquid, place it in the wound and then cover with dry tow. The U. S. Bureau of Animal Industry directs that the foot be carefully cleaned and every portion of detached horn be cut away. Should there be fungoid granulations, these should be removed with a knife or a pair of curved scis- sors. All clippings and trimmings that are removed from diseased feet, whether composed of bits of horn, shreds of tis- sue or fungoid growths, should be care- fully gathered up and burned or disin- fected, as they may serve to spread the disease further if left where other sheep may come in contact with them. After THE STANDARD FORMULARY Foot Rot, Treatment for (Cont'd). trimming the feet, stand the sheep for 10 minutes in a solution of copper sul- fate made from 3 pounds of this salt to 5 gallons of water. The solution when used should be as warm as can be borne by the hand. The bath should be re- peated if necessary. It sometimes happens that the disease assumes an aggravated form in several of the sheep, involving the deeper tis- sues and necessitating the application of dressings. In such cases all the loose and diseased tissues should be cut away and the affected parts washed thorough- ly with a 5% solution of carbolic acid, then the below-mentioned antiseptic as- tringent powder should be dusted on and a bandage applied. Tannic acid gr. 75 Carbolic acid gr. 150 Exsiccated alum av.oz. 8 The verdigris ointment mentioned un- der Foot Rot, Remedies for, in Division II, may also be used for sheep. Goitre, Remedies for. Iodids in conjunction with mercurial ointment and salicylic acid is the usual application as indicated in these two formulas. I. Potassium iodid av.oz. x / 2 Water fl.oz. x / 2 Mercurial ointment av.oz. 4 Applv once dailv to the swelling. II. Salicylic acid gr. 45 Potassium iodid av.oz. V 2 Water fl.oz. 2 Simple cerate av.oz. 2 To be used like the preceding. Insects, To Prevent Attacks of. Sheep are annoyed a great deal with insects, especially flies. Mercurial oint- ment is an excellent repellent for in- sects but, on account of its poisonous character is not to be recommended. The following is useful: Xaphthalin av.oz. 1 Cottonseed oil fl.oz. 2 Water fl.oz. 2 Soft (or green) soap av.oz. 5 This is to be applied as frequently as may be necessary. Itching of the Skin. Itching of the skin is caused by not sending the sheep to pasture. The ail- ment is neither dangerous nor contagi- ous. Treatment consists in applying the following lotion and putting the animals to pasture. Boric acid gr. 75 Carbolic acid m. 75 Water fl.oz. 16 Mix and dissolve. Apply this lotion once daily to the in- flamed spots. Mange Remedies. See Scab, Treatment for. Rheumatism Remedies. Rheumatism is usually caused by ex- posure to cold; it manifests itself by limping and lameness. Treatment con- sists in keeping the animal warm, rub- bing it well twice a day and bathing once daily with weak salt water. Ca- thartics should be given internally. I. For bathing. Rosemary herb, cut av.oz. 4 Soda ash av.oz. 16 Sodium chlorid av.oz. 64 Mix the above with 12 gallons of hot water, allow to stand for 15 minutes, and use for bathing. The liquid may be used 2 or 3 times for a bath if warmed each time. It should be lukewarm when used. II. For liniment. Oil of turpentine fl.dr. 4 Water of ammonia fl.dr. 4 Spirit of soap fl.oz. j l / 2 Spirit of camphor fl.oz. J l / 2 Rub the legs with this mixture twice daily. III. For a cathartic for full-grown animals. Sodium sulfate av.oz. i l / 2 Aloes gr. 80 Linseed oil, raw fl.dr. 5 Decoction of linseed (1 in 20) fl.oz. 7 Mix and dissolve. Give one-half at a dose and repeat in 3 hours. SHEEP MEDICINES. 639 IV. A cathartic for lambs. Sodium salic}-late dr. I Aloes dr. 6 Decoction of linseed (i in 20) fl.oz. 15 Mix and dissolve. Give a teaspoonful 2 or 3 times daily, according to the age of the animal. Scab, Treatment for. Scab is one of the most dangerous of the parasitic diseases of sheep. It is due to a minute insect called acarus, about the size of a pin head, which bores into the skin, hatches and multiplies, the young spreading to other portions of the animal's skin, there to continue the same process. Treatment consists of either rubbing poisonous ointments into the fleece by hand or by immersing the sheep in aqueous mixtures containing some in- gredient which will kill the parasites. When any of the flock are infected, all should be dipped, preferably being first sheared if the season permits it. Instead of treating the scab by one application, some authorities advise the use of a preliminary dip of alkaline wa- ter to soften, the scabs, or of oil or glycerin well rubbed in for the same purpose. This is to be followed in 2 or 3 days by a poisonous dip. Nearly all advise that the scabs be rubbed with a stiff brush while the sheep is being dipped. The quantity of dip required for each sheep is variously estimated at from 1 quart to 1 gallon, For small numbers of sheep, say, 50 to 100, the larger amount is necessary, while for large flocks, 1 quart for shorn or 2 quarts for unshorn sheep may be allowed. The dip should be kept while in use at a temper- ature of from 100 to no F. The sheep should be dipped again within some 6 or 10 days of the first dipping in order to kill before their maturity any para- sites which may have developed from eggs which were left upon the animal at the time of the first treatment, as the dip does not destroy the vitality of the eggs. The chief poisons used in the dip are tobacco, arsenic and carbolic acid. Of these, tobacco is the favorite, because its use has not been followed by the fatal- ity that has in times past followed the use of arsenic. Carbolic acid is too ex- pensive to be used in large quantities, but is an excellent ingredient when only a few sheep are to be treated. The ad- dition of tar to the dips serves a good purpose, as it is not only healing, but serves an excellent purpose in driving away flies. The following three formulas are rec- ommended by the U. S. Department of Agriculture. They are stated to be rath- er prophylactic in character and are used generally after shearing. Carbolic Acid Dip. Soap av.lb. 1 Crude carbolic acid fl.oz. 16 Water gal. 50 Dissolve the soap in a gallon or more of boiling water, add the acid and stir thoroughly. Any kind of soap may be used, such as laundry soap or soft soap. Keep the mixture well thinned in us- ing and do not let it get into the mouth, nostrils or eyes of the sheep. Hold each sheep in the bath not less than half a minute. Kerosene Emulsion Dip. Fresh skimmed milk gal. 1 Kerosene gal. 2 Churn together till emulsified, or mix and put into the mixture a force pump and direct the stream from the pump back into the mixture. The emulsion will take place more rapidly if the milk be added while boiling hot. Use 1 gal- lon of this emulsion to each 10 gallons of water required. Kerosene Soap Dip. Soap av.oz. 16 Water gal. I Kerosene gal. 2 Bring the water to a boil and dissolve the soap in it ; then add the kerosene 640 THE STANDARD FORMULARY Sheep Dip (Cont'd), and churn until emulsified. Use I gal- lon of this emulsion to 8 of water. Texas Tobacco Dip. Tobacco av.lb. 30 Sulfur av.lb. 7 Concentrated lye av.lb. 3 Water gal. 100 Steep the tobacco in three successive portions of water, expressing each time : then add the other ingredients to the li- quor, and stir well while in use. Law's Sheep Dip. Tobacco av.lb. 16 Oil of tar fl.oz. 48 Soda ash or caustic soda. . .av.lb. 20 Soft soap av.lb. 4 Water gal. 50 Steep the tobacco as in the previous formula, and add the other ingredients to the liquor. Zundels' Carbolic Dip. Crude carbolic acid av.lb. 3 Unslaked lime av.lb. t 2 Potash or lye av.lb. 6 Soft soap av.lb. 6 Water gal. 70 Mix and boil. Kaiser's Carbolic Dip. Tobacco , av.lb. 13^ Soda ash or caustic soda.. av.lb. 8 Soft soap av.lb. 8 Freshly slaked lime av.lb. 4 Crude carbolic acid av.lb. 4 Water gal. 66 Infuse the tobacco in the water, strain, and to the infusion add the remaining ingredients. The carbolic acid should contain 50% phenol. The following arsenical preparations are in favor in England: Arsenical Sheep-Dip Paste. (Finlay Dunn.) Arsenic av.lb. 2 Pearlash av.lb. 2 Soft soap av.lb. 2 Sulfur av.lb. 2 This is sufficient for 125 gallons of water. Arsenical Sheep-Dip Paste. (Prof. Simonds.) Arsenic av.lb. 1 Soft soap av.lb. 1 Potassium carbonate av.oz. 8 Water gal. 4 Boil the arsenic and potash together in half the water, and dissolve the soap in the other half. This is sufficient for 20 sheep. It should be used warm. While the last two preparations are efficacious they are not recommended on account of their poisonous nature and unless special precautions can be taken to. avoid contaminating the pastures or otherwise poisoning the animals. Lime and Sulfur Dip. The following three formulas for sheep dips have been approved by the British Board of Agriculture: Mix 25 pounds of sulfur with l2 l / 2 pounds of good quicklime. Triturate the mixture with water to a smooth cream and transfer this to a boiler of 20 gal- lons capacity. Make up the volume with water to 20 gallons, boil and stir during half an hour, when the liquid should have a dark red color. If yellowish, continue the boiling until the dark red color is obtained, keeping the volume at 20 gallons. When the liquid has cooled decant off from any small quantity of insoluble residue and make up the vol- ume to 100 gallons with water. Carbolic Acid and Soft Soap Dip. Dissolve 5 pounds of good soft soap, with gentle warming, in 3 quarts of good crude carbolic acid. Mix the liquid with sufficient water to make 100 gal- lons. Tobacco and Sulfur Dip. Steep 35 pounds of finely ground offal tobacco in 21 gallons of water for 4 days. Strain off the liquid and remove the last portions of extract by pressing the residual tobacco. Mix the whole ex- tract and to it add 10 pounds of sulfur. Stir the mixture well to secure an even admixture and make up the total bulk to 100 gallons with water. SHEEP MEDICINES. 641 Scurvy, Remedies for. This frequently affects young merino lambs and is due to some deficiency in the mother's milk. The lamb refuses to take nourishment, white canker spots appear both internally and externally and the gums become blue. Treatment consists first in proper feeding of the mother sheep, such as going out to green pasture and giving the lamb the follow- ing mixture : Hydrochloric acid fl.dr. 3 Infusion of angelica (1:- 20) to make fl.oz. 8 Give a tablespoonful twice daily. The sick animals must be fed by pour- ing the milk into their mouths. The canker spots should be treated as de- scribed under Thrush, Remedies for, No. III. Tape Worm Remedies. See Worm Remedies. Thrush, Remedies for. Thrush in lambs is due to some dis- turbance of nutrition. The treatment consists in giving the mother sheep a purgative, and to the lamb a mild alka- line laxative, also washing its mouth with water containing a small amount of vinegar and subsequently applying the lotion mentioned below. I. Purgative for the mother sheep : Sodium sulfate .av.oz. 2^ Sodium bicarbonate dr. 2^ Sodium chlorid . , dr. 2^ Gentian dr. 2^/2 Reduce all to powder and mix well. Mix this with a pint of water, give one-half of it at a dose and the remain- der in 2 hours. II. Laxative for the lamb: Rhubarb, powder dr. 1 Magnesium carbonate ... ..... dr. 2 Give as much as will lie on the point of a knife 3 times a day in water. III. Application to the canker spots: Borax, powder dr. 3 Honey av.oz. 2 Tincture of myrrh fl.dr. 3 Peru balsam m. 90 Rub the borax with the honey and incorporate the other ingredients. Wash the growth out 5 or 6 times daily with fresh water, then apply this preparation. Tim should be well shaken before using. Tympanitis Remedies. See Tympanitis Remedies, Division II, for description of causes and symptoms. As in cattle the attack must be immedi- ately relieved as otherwise it proves fa- tal. The following remedy is recom- mended: Ammonia water fl.dr. 4 Spirit of soap fl.oz. 3^2 Give a tablespoonful in a cup of milk every 15 minutes. If this fails to re- lieve, then puncture the stomach with a trochar as described under Cattle Medi- cines. Urine, for Retention of. Retention of urine may be caused by a "cold" but may also be due to stone in the bladder. If caused by the latter, op- erative measures are necessary; if by the former, the following may be used : Hemp seed av.oz. 2 Magnesium sulfate av.oz. 1 Juniper berries av.oz. Yz Rye flour av.oz. y 2 Bitter almonds gr. 90 Reduce all to powder, mix and ma^ an electuary by the addition of water or syrup. A piece the size of a marble may be given once daily. TJrine, for Bloody. This condition may be caused by acids or by oxalates in the fodder. The animals should be placed in a warm stall and fed with wholesome food, either dry or green. The follow- ing may also be given: Lead carbonate av.oz. y 2 Camphor av.oz. }4 Bitter almond av.oz. I Linseed meal av.oz. 3 Rye flour av.oz. 5 All should be reduced to powder and be made into a stiff mass with syrup or molasses. A piece the size of a hazelnut should be administered once daily. 642 THE STANDARD FORMULARY Womb, for Inflammation of. Inflammation of the womb of sheep is infectious and affects sheep either be- fore or after giving birth. If the for- mer, the foetus dies and quickly decom- poses. The vaginal orifice then becomes red and inflamed and from it oozes a foul-smelling fluid. To avoid this con- dition it is recommended to apply the salve (No. I) to the mouth of the womb to remove the foetus, and then use anti- septic douches for the vagina. Internal- ly give the preparation mentioned below (No. II). I. Extract of henbane dr. 2^ White of egg dr. 2 1 /, Lard dr. 2 l / 2 Make a salve, which is to be applied every 2 hours to the mouth of the womb. II. Bitter almond gr. 75 Sodium salicylate gr. 150 Magnesium sulfate av.oz. 2 Decoction of linseed (1:- 10) fl.oz. 6 Give a tablespoonful every 2 hours. Worm Remedies. For tape worms, use the following : Aloes gr. 150 Oleoresin of male fern gr. 30 Naphthalin gr. 3 Make into a mass with spirit of soap and divide into 2 pills. The dose for a lamb, 4 to 8 months, is 1 pill given in the morning without giv- ing food; the other pill should be given 8 days thereafter. The dose for lambs only is given, as full-grown animals are rarely affected. For remedies for twisted wire-worms and hook-worms, see Worm Remedies in Division II. DIVISION IV.— SWINE MEDICINES. Many of the remedies mentioned un- der the sections relating to horses and cattle may also be used for the treat- ment of pigs. Appetite, Loss of, Tor. Loss of appetite may be indicative of other diseases, but may also be the re- sult of overfeeding or due to the pres- ence of undigested food. Treatment consists in changing the food, giving an emetic, and subsequently the powder mentioned below. I. Give at one dose as an emetic: Tartar emetic gr. 15 Ipecac, powder gr. 45 Althaea root gr. 75 Mix and make into an electuary by means of syrup, molasses or mucilage. II. Calamus av.oz. 1 Gentian av.oz. 1 Black antimony av.oz. 1 Sodium bicarbonate av.oz. 5 Sodium chlorid av.oz. 5 Sodium sulfate av.oz. 5 Mix all and reduce to powder. Give a tablespoonful twice daily. Catarrh Remedies. Catarrh in pigs is usually due to "cold" caused by rapid changes of tem- perature such as occur in the spring or autumn. The animals have diminished appetite but increased thirst, and the eyes and mucous membrane of the mouth are inflamed. From - the nose flows a secretion, watery at first, later becoming mucous, and the animals cough violently. Generally the affection subsides of itself. If there is an accom- paniment of fever, cathartics containing antifebrile agents, or emetics, should be administered. I. Ammonium chlorid av.oz. J /2 Black antimony av.oz. J /> Argols . (crude tartar) av.oz. 1 Licorice root av.oz. 2.y 2 Linseed meal av.oz. 2^2 Mix in powder and add syrup to form an electuary. Give a piece about the size of a wal- nut 3 times daily. SWINE MEDICINES. 643 II. Emetic : Tartar emetic . . . gr. 15 Ipecac, powder gr. 45 Mix with syrup or honey and admin- ister to the animal by smearing the whole on the tongue. Colic Remedies. Colic may result from eating difficultly digestible food or poisonous plants, from exposure to cold, or from worms. Treatment consists in keeping the ani- mal in a warm stall, administering aro- matic, stimulating and purgative reme- dies, and giving enemas every half hour. I. Sodium sulfate av.oz. 1^2 Peppermint av.oz. y?. Sodium chlorid gr. 150 Reduce all to powder and mix well. Give one-half of this mixture in 8 fluidounces of weak coffee and repeat the dose in 3 hours. II. For enema: Chamomile av.oz. l /^_ Peppermint av.oz. Yi Green soap av.oz. 2Y2. Linseed oil, raw fl.oz. 2^ Water, boiling fl.oz. 48 Pour the water upon the chamomile and peppermint, let stand for 15 minutes, strain, and add to the colature the re- maining ingredients. Inject 8 fluidounces of this mixture, previously warmed, into the rectum every half hour. If the colic is caused by worms, a vermifuge should be administered to avoid the attacks of colic. See Worm Medicine. Diarrhea Remedies. Diarrhea may result from exposure to cold or from disorders of digestion. If it continues more than 24 hours, treat- ment is urgently demanded, as it may become severe. The animal should be kept warm, and astringent and aromatic remedies may be given, and possibly suppositories may be required. I. Ferrous sulfate gr. 40 Alum gr. 40 41 Sugar of milk - gr. 300 Acacia gr. 400 Mix all in powder and divide into 5 parts. Give I powder in a cupful of warm chamomile tea or other suitable vehicle every 3 hours. II. Rhubarb gr. 15 Calcium carbonate gr. 150 Mix in powder and divide into 10 por- tions. One portion is to be given twice daily in a tablespoonful of warm chamomile tea or other suitable vehicle. This rem- edy is intended for suckling pigs. Eye, Inflammation of the. Inflammation of the eyes occurs fre- quently in young pigs and may be caused by other ailments or by mechanical in- jury. Wash the eye 3 times daily with luke- warm water and use the following eye waters : 1. Zinc sulfate gr. 10 Tincture of opium m. 20 Infusion of chamomile (1 in 50) fl.oz. 4 II. Ammonium chlorid gr. 18 Lead water g fl.oz. 4 Founder, Remedies for. Founder is of rheumatic origin and is accompanied by disorders of digestion. The animal walks stiff, has pain in its limbs, appetite is lessened, the feces are dark and hard, and the urine is yellow- ish-brown. Treatment consists in rub- bing the animal, giving an emetic, and, several hours after this has acted, a purgative. To the legs apply counter- irritants. I. To produce vomiting : Copper sulfate gr. 15 White hellebore gr. 30 Sugar gr. 75 Reduce all to powder and mix well. Give at one dose on the tongue. 644 THE STANDARD FORMULARY Founder (Cont'd). II. Purgative : Sodium nitrate gr. 80 Gentian dr. 2^ Linseed meal dr. 5 Sodium sulfate av.oz. i l / 2 Give one-half in a pint of warm water and the remainder in 3 hours. III. Application : Cantharides, powder av.oz. l A Euphorbium, powder av.oz. l A Salicylic acid av.oz. l / 2 Suet av.oz. 1 Sweet oil av.oz. 1 German soft turpentine av.oz. \Vx Mix together and keep at a gentle heat for an hour. Rub the animal's legs up to the shoul- ders and thighs once a day for two suc- cessive days. Hog Cholera Remedies. Hog cholera, swine fever and swine plague are the names applied to a group of symptoms produced by three distinct types of disease, namely, charbon, con- tagious pneumo-enteritis and epizootic catarrh, all, however, dependent upon recognized specific germs. The second form, pneumo-enteritis, probably is the one most commonly understood, and it is characterized by an inflamed, ulcerat- ed condition of the alimentary tract, and fetid, bloody discharges — these having determined the popular designation of "cholera." As soon as an animal develops symp- toms of the plague it must be isolated from the herd and surrounded by abso- lutely antiseptic conditions. Constipa- tion, if present, should be relieved by castor oil or rhubarb. The bowels should be frequently irrigated with warm wa- ter; one of the below-mentioned pre- scriptions should be administered; the food should be restricted to well-cooked oat or barley meal gruel, or, if this is not borne, boiled corn starch. Some ad- vise putting a trace of sulfuric acid into the drinking water. For the fever po- tassium nitrate usually is resorted to. In the convalescent stages tonics must be administered. When the disease is fully developed there is little hope and the animal should be killed and buried with quicklime. In England swine fever comes under the contagious diseases act, and treatment is not permitted. The public health au- thorities must be advised, who destroy the infected animal. Prophylaxis consists in keeping the animal in perfect health by insuring proper hygienic food and surroundings. One of the principal, if not the main, cause of the disease is excessive feeding of corn. Corn-fattened animals are not in a physiological condition, as is well understood, and corn, principally con- sisting of starch, being particularly prone to fermentation, naturally must favor development of fermentative dis- eases in debilitated organisms. Hence corn should largely be replaced by the grains, bran, peas, beans and other ni- trogenous foods, which will produce more muscle and less unhealthv fat. De- caying and fermenting food should not be offered under any condition. Clean, ventilated stalls that will afford protec- tion against inclement weather, but also plenty of exercise in the open air, are prerequisites. Prophylactic treatment consists in the daily administration of wood or animal charcoal or iron sulfate. Potassium chlorate is also recommended. In fact, experience teaches that the two latter agents are the only ones which proved effective for this purpose or in treating the initial stages of the disturbance. A few methods of treatment are here given. I. Arsenic av.oz. 1 Black antimony av.oz. 4 Potassium nitrate av.oz. 4 Ferrous sulfate av.oz. 16 Sulfur av.oz. 16 Madder av.oz. 16 Mix with 12 gallons of slop, and give 1 pint to each hog, the whole being for fifty. SWINE MEDICINES. 645 II. . av.lb. i .av.lb. 2 .av.lb. 2 .av.lb. 5 .av.lb. io .av.oz. .av.oz. .av.oz. .av.oz. .av.oz. Capsicum Ferrous sulfate Madder Calcium phosphate . . Wood ashes, sifted.. This may be administered in the same quantity as the foregoing. III. Iron carbonate Sodium chlorid Potassium carbonate Sulfur Lime Carbolic acid fl.oz. 5 Magnesium carbonate av.oz. io Soap av.oz. io Mix well and reduce to powder. One-fourth av. ounce should be given at each meal, mixed with the food. IV. Wood charcoal av.oz. 4 Sulfur av.oz. 4 Sodium sulfate av.oz. 4 Black antimony .av.oz. 4 Sodium chlorid av.oz. 8 Sodium bicarbonate av.oz. 8 Sodium hyposulnte av.oz. 8 Reduce all to powder and mix well. A large tablespoonful for each 200 pounds of animal should be given once daily with food. This has been highly recommended for this particular disease. It is said even to be a preventive of hog cholera. V. The following are the U. S. Pat- ent Office specifications for a medicine for the cure of hog and chicken cholera, the patent being granted in 1871 : To 5 gallons of water add 5 pounds of blackberry root. Let this boil thor- oughly for 1 hour, after which take out the roots, and while the water is boiling add Yz pound of bruised allspice, 1 ounce of tincture of iron, I ounce of asafetida, and y 2 ounce of gum cam- phor. Let it continue to boil about 20 minutes, then strain through a fine sieve, and then reduce the liquid by boiling to I gallon, which when cooled, may be bottled for use. In administering to hogs, for every dozen hogs, take 5 gallons of scalded bran slop and add 4 ounces of the medi- cine. This should be given every morn- ing while threatened with the disease or while actually sick. In administering to chickens or other fowl, for every dozen taken 2 quarts of. corn meal, y 2 pint of lard and 3 table- spoonfuls of medicine. Mange Remedies. Pigs are occasionally affected by mange, the site of the affection being on the inner surface of the thighs and be- low the eyes. The animal tries to rub itself and then loses its bristles. The following application is advised : Sulfurated potash, powder, .av.oz. 1 Cottonseed oil av.oz. 1 Soft (or green) soap av.oz. 9 Mix well. Apply this mixture to the affected spots, wash the animal in 2 days with warm water, and again apply this paste. Milk Fever, Treatment for. Milk fever is often caused by expo- sure to cold, but may be produced by other as yet unknown causes. The com- plaint is a serious one and must be treated in its early stages, otherwise it proves fatal. Treatment consists in vigorous rub- bing of the animal, giving enemas, and internally administering mild laxative and antifebrile remedies. The suckling pigs should be applied to the teats as frequently as possible. I. Magnesium sulfate ... .av.oz. 2 Potassium nitrate dr. 2 Rye flour dr. 2 Water fl.oz. 4 Stir the solids with the water (cold), then heat to boiling, and allow to cool. Give 2 tablespoonfuls every hour. This is a laxative and antifebrile. II. For enema: Sodium salicylate gr. 90 Egg yolk gr. 30 Milk fl.oz. 7 Divide into 2 parts to be given as enemas 2 hours apart. The liquid is t l / 2 Use like the preceding. Tonic Medicine. I. Tincture of iron chlorid drops 4 Tincture of cinchona fl.dr. I BIRD MEDICINES. 657 Glycerin fl.dr. 2 Caraway water, to make fl.oz. 2 Put a few drops on a lump of sugar in the cage daily. II. Iron sulfate dr. 2 Diluted sulfric acid drops 15 Water fl.oz. 8 Dissolve the sulfate in the water and add the acid. A teaspoonful of this mixture is to be added to each quart of the drink- ing water of the birds. This is specially recommended for moulting birds. This preparation is known as Doug- lass' Mixture. Gapes in Pheasants. Ferrous sulfate gr. 60 Capsicum Fenugreek Red 'saunders Licorice root Molasses . . . .av.oz. x / ....av.oz. 1 ....av.oz. 1 ....av.oz. 2 sufficient This is made into a paste, of which a piece the size of a hazelnut is dis- solved in a gallon of water and given the birds to drink. Ointment, Healing and Soothing. Peru balsam . , gr. 60 Cold cream av.oz. 1 This is of general application when an ointment is needed for birds. Part III PROPRIETARY AND SYNTHETIC REMEDIES. Reference Abbreviations. A. D American Druggist A. J. P. ..American Journal of Pharmacy Apoth. Ztg Apotheker Zeitung B. & C. Dr... British & Colonial Druggist Cooley Cooley's Cyclopedia D Dietrich's Manual D. C Druggist's Circular Drog. Ztg Droguisten Zeitung Era Form Era Formulary Fenner's Form Fenner's Formulary H Hager's Praxis or Manual Ind. Ph Indiana Pharmacist Kilner's Form Kilner's Formulary Nat. Dr National Druggist N. I New Idea Parish Parrish's Pharmacy Pharm Pharmacist Ph. Central. Pharmaceutische Centralhalle Ph. Era Pharmaceutical Era Ph. Post Pharmaceutische Post Ph. Rundsch. Pharmaceutische Rundschau Ph. Ztg Pharmaceutische Zeitung W. D Western Druggist NOTE The Preparations in this part having titles followed by a number are Proprie- tary or controlled by a single manufac- turer, the number indicating the name and address of the manufacturer as given in the reference list at the end of the Part. It is believed this information as to the makers of the various proprietaries will prove valuable to all desiring to re- quest further information from the orig- inal sources. In this department the attempt is made to include as many as possible of the synthetic; and pseudo-synthetic remedies, most of the so-called pharma- ceutical specialties, and some of the "patent" medicines. The reason for com- bining these dissimilar classes together is that many of the pharmaceutical spe- cialties and some of the "patent" medi- cines bear names similar to the synthetic remedies. The pharmaceutical special- ties and "patent" medicines are them- 42 selves frequently indistinguishable, due to similarity of titles. In describing synthetic remedies, the plan generally followed is to mention the chemical names or synonymns, physi- cal, chemical and medicinal properties, incompatibilities and doses. In describ- ing pharmaceutical specialties, physical and medicinal properties and doses are mentioned as well as composition. In- formation regarding the composition is taken from manufacturers' catalogs or from the statement on the label (in compliance with the provisions of the federal food and drugs act) or from the booklets published under the auspices of the American Medical Association. In- formation regarding "patent" medicines is also taken whenever possible from the manufacturer's statement on the label and at other times from other sources of information which are sup- posed to be credible. The formulas giv- en in the latter instances are quoted simply for what they are worth, con- sidering the fact that chemistry has not advanced sufficiently to make possible an analysis of a complex organic mix- ture and also considering that manufac- turers are at liberty to change their formulas at any time. The source of information is given in most cases and is believed to be re- liable, but, should any formula, by rea- son of any incorrect statement or in- ference, be regarded as unjust to the original preparation or as impairing its reputation, the correction will be cheer- fully made upon receipt of the requi- site information. 660 THE STANDARD FORMULARY •S o oj a v5j 3 P « O o ° £ °* coo,o. So ■So £5 £§ o*HL ^J^Z^. iHb« 0) 3-. •9 2 2 o)o a w> 3 c3 *5 ft, HO W 3 §0 a) 3x:£> OPQQOOe-ico 4 O 0.3 3 3^ .3.3 o. ft A, o.S ° O 3 3 be 3 ■X c cuto £<£h«! «- !- O-O ej u^ o £ o o o B PROPRIETARY AND SYNTHETIC REMEDIES. GG? A. B. C. Headache Powders. Each powder is stated to contain : Monobromated camphor gr. Y% Caffeine gr. Vs Sodium bicarbonate gr. 2 Acetanilid gr. 3^2 Sugar gr. 1/2 Saccharin and peppermint. . .a trace Abbott's Saline Laxative. This is stated to be chemically pure magnesium sulfate in effervescent form. Abernetky's Pills. - Each pill contains : Socotrine aloes gr. 2 Extract of henbane gr. 2 Blue mass gr. 1 — Fenner's and Beasley's Formularies. Abican. (173) This is described as a non-alcoholic, stainless preparation from Abies cana- densis with "alumen potas," zinci sulfas, and thymol. It is recommended in the treatment of gonorrhea, gleet, leucor- rhea, and all abnormal urethral and vaginal discharges. Abrastol. See Asaprol. Abrin — (Jequiritin.) This is an albuminous substance de- rived from jequirity seeds. It is a brownish-yellow powder, soluble in water. It is an exceedingly poisonous substance. It is very dangerous, especi- ally to the nose, eyes, and wounds, and hence great care should be exercised in handling it. Acacine. (73) This is a white powder, used as an emulsifying agent. Acamulsia. This is an emulsifying agent, formula for which is as follows : Acacia av.oz Tragacanth Starch Sugar Boric acid Reduce all to powder and mix well. The mixed powder is to be used in the proportion of l / 2 ounce to a pint of emulsion. 8 ounces of oil is to be put the 5 .av.oz. 5 .av.oz. 5 .av.oz. 5 .av.oz. 1 into a quart bottle and shaken, then the acamulsia is to be added, the mixture, then well agitated, 8 ounces of water to be added and the whole shaken vig- orously for a few minutes. Acetal — (Ethylidenediethylether.) It is a colorless, volatile liquid, sol- uble in 18 parts of water and in all proportions of alcohol and ether. It is used as a hypnotic and sedative, where chloral would be contraindicated. The dose is 2 or 3 fluidrams, usually given in the form of emulsion. Acetanilid — (Phenylacetamide.) This is in white, shining scales or white powder, odorless, and of a slightly burning taste. It is used as an antipyretic, anal- gesic and antirheumatic, also now largely used externally as an antiseptic in place of iodoform. It is used in headache, neuralgia, and in injection mixtures for gonorrhea. Dose : 3 to 10 grains, the maximum single dose being about 20 grains, pref- erably used in powders, tablets, cap- sules or cachets. Acetanilid Comp. The combination usuauy put up under this name is a mixture of 7 parts of acetanilid, 2 parts of caffeine and 1 of sodium bicarbonate. Other mixtures are used under the same name. Acetanilid Comp. Dr. Bower's. (108) These are tablets each said to con- tain Acetanilid gr. 3 Monobromated camphor gr. 2 Caffeine citrate .gr. 1 Acetic Cantharidal Vesicant. Cantharides, freshly pow- dered av.oz. 8 Acetic ether sufficient Moisten the drug with the liquid, pack firmly in a percolator, add more men- struum, macerate for a few hours, and then percolate slowly until 16 fluidounces of liquid have been obtained. Liquor Epispasticus or Blistering Li- quid of the British Pharmacopeia is of 662 THE STANDARD FORMULARY the same strength as the above and is made with the same menstruum. Acetocaustin. This is a 50% solution of trichlora- cetic acid, which is used as a caustic for warts, corns, etc. Acetopyrin. This is a combination of antipyrin and aspirin. It is in the form of a colorless, crystalline powder, insoluble in cold water but readily soluble in warm water and alcohol. It has an odor of acetic acid which would indicate a rather unstable product. It is recom- mended not only as an efficient anti- pyretic but is said to have proved bene- ■fkial in acute rheumatism and neural- gia. Acetozone (Benzozone). (159) Chemically, this is benzoylacetyl per- oxid, which belongs to a class of com- pounds known as organic peroxids in which an excess of oxygen is combined in such a way that it is slowly given off m a nascent condition. On contact with water it hydrolyzes, forming benzo-per- acid and aceto-peracid which exert mark- ed oxidizing and germicidal properties. These compounds decompose later with the formation of hydrogen peroxid and then of oxygen. It is a grayish white substance appearing in the form of a micaceous powder, which is marketed as a mixture consisting of equal parts of pure acetozone and an inert soluble powder. It is very readily decomposed and must not be kept in a hot location such as near a window where the rays of the sun can strike it, or near a steam pipe or radiator. If it be heated to the boiling point of water, an explosion may result. Contact with moisture should be avoided except when neces- sary in dispensing. In the pure state it dissolves in 1,000 to 10,000 parts of water, 20 of oil, is slightly soluble in alcohol, more so in ether and chloro- form, but slowly decomposing in all these solutions except in petrolatum oil. It is decomposed by contact with alka- lies and organic matter of all kinds (e.g. glycerin). It is a powerful antiseptic and is used chiefly internally in typhoid fever, and externally to some extent in surgery; it is also used as a vaginal or urethal in- jection in gonorrhea. In typhoid fever it is added to water in the proportion of 1 to 1,000 of warm water, shaken vigor- ously for 5 minutes, allowed to stand for 2 hours, and then solution is drank freely, say 2 quarts or more in 24 hours. Acetozone Inhalant. This contains 1%. of acetozone, J/2% of chloretone and 98^% of colorless liquid petrolatum. Acet-Theocin-Sodium. See Theocin-Sodium Acetate. Acidol (Betaine Hydrochloride This is in white crystals of a sour taste, readily soluble in water. It con- tains 24% of hydrochloric acid and is used as a substitute for the latter usu- ally in combination with pepsin in gas- tric affections. The dose is 2 to 10 grains. Acodine. This is a dental preparation said to consist of aconite, iodin, tannic acid and glycerin. Acoin. This is one of the newer local an- esthetics. It is a white, ordorless, very bitter powder, soluble in 17 parts of water, freely soluble in alcohol. It is very readily affected by alkalies and is also sensitive to light. It has been recommended for Schleich's infiltration anesthesia method in 1/10% solutions containing 8/10 % of sodium chlorid. Actina. Various formulas have been offered for similar preparations, as follows : I. Menthol gr. 60 Oil of mustard fl.dr. 2 Alcohol m. 30 Ether fl.dr. 1 Sponge, to make oz. 1 —Prof. F. B. Tiffany, K. C. PROPRIETARY AND SYNTHETIC REMEDIES. 663 II. Menthol gr. 60 Oil of mustard fl.dr. 2 Hydrobromic ether fl.dr. 1 Sponge, to make oz. 1 — Prof. Tiffany. Actol. (Silver Lactate.) This is a white, odorless, almost taste- less powder; soluble in 15 parts of water or albuminous fluids; an external and internal antiseptic in chronic and acute infectious diseases, sore throat, etc. It is used as a gargle and wash. Mix a teaspoonful of 2% solution with a glass of water, or use a solution of 1 1500 to 1 :20O for disinfecting wounds, abscess cavities, etc. The dose by injection Y\ to 3 grains, singly or divided. The solu- tions should be prepared fresh with boiled, distilled water and should be kept in the dark. Addison's Granules of Arsenate of Gold. These are stated to contain about 1/120 grain of gold arsenate. This salt is not introduced directly but is obtained in the finished pill by using gold and sodium chlorid and sodium arsenate in the proposition of 2.7 grains of the for- mer and 8 of the latter to make 15 grains of gold arsenate. — H. Adhoesol. Copal resin parts 70 Benzoin parts 6 Tolu balsam parts 6 Oil of thyme parts 4 Alphanaphthol parts 6 Ether parts 200 —Merck's Bulletin. This is an antiseptic dressing or var- nish, used in the treatment of superfi- cial injuries. Adipatum. Anhydrous wool fat parts 35 Petrolatum parts 53 Ceresin, white parts 7 Water parts 5 This is used as an ointment vehicle. Adipogen. This is a preparation of the fresh liver of the codfish which is the subject of a U, S, patent. According to Chit- tenden's analysis it contains 51.38% of codliver oil, 11.02%. of proteid matter, 5.11% of mineral acids, and 0.57% of phosphoric acid. It is a paste of pleas- ant fishy odor. The dose is a teaspoon- ful 3 or 4 times a day. It may be eaten by spreading it on bread like butter. Adnephrin Emollient. (187) This is described as an ointment com- posed of the adrenal (suprarenal) active principle and a neutral base, represent- ing in each 1,000 parts, 1 part of the active principle. Adnephrin Oil Spray. This is a 1 in 1,000 solution, aroma- tized, of the active principle of the su- prarenal glands in a neutral oil. It is used as a nasal and throat spray, pref- erably after cleansing with Dobell's solu- tion. Adnephrin Solution. This is described as a liquid, each 1,000 parts of which contains 1 part of adnephrin, the active principle of the suprarenal glands, dissolved in a sterile, physiologic salt solution containing l / 2 % of methaform as a preservative. It is practically neutral in reaction, non-irri- tating, and stable in character. It is said not to turn pink. It is of value in minor surgical operations by checking the hemorrhage and affording a clear view of the field of operation. Adonidin. A glucoside obtained from Adonis vernalis. It is a hygroscopic, yellowish- white, odorless, bitter powder. It is eas- ily soluble in water and alcohol; insol- uble in ether and chloroform. It is a heart-tonic and diuretic, particularly in aortic and mitral insufficiencies. Dose : 1/12 to % grain several times daily, in pill, or in solution in chloro- form water with ammonium carbonate. The maximum dose is l / 2 grain. Adorin. (178) This is a powder used to prevent per- spiration of the hands, feet, etc. It is stated to contain formaldehyde. .;»;! THE STANDARD FORMULARY Adrenalin. (159) This occurs as tiny, white crystals which are soluble in water slightly acid- ulated with hydrochloric acid and yields solutions that assume a pink color on standing. Solutions should therefore not be kept for any great length of time; preferably they should be made fresh as needed. So powerful is this substance that a drop of a solution of I part in 10,000 when instilled into the eye will blanch the conjunctiva in from 30 seconds to 1 minute. Bloodless operations have been performed after the application of the weak solution. Internally adrenalin may be used as a cardiac stimulant. Adrenalin is also marketed in the form of adrenalin inhalant, adrenalin ointment, adrenalin suppositories and adrenalin tablets. Adrenalin Chlorid Solution. This is a solution containing 1 part of adrenalin chlorid in 1,000 parts. Each fluidounce is stated to contain % grain of adrenalin chlorid, 2 l /\ grains of chloretone (equal to l A%) and physi- ological salt solution, q. s. It is used generally in the form of a spray, the solution varying in strength from 1 to 1,000 to 1 to 15,000, or internally in doses of 5 to 30 minims. It causes con- traction of the arterioles, rendering the parts it affects bloodless. Mucous mem- branes are blanched by its application ; this is particularly noticeable when it is instilled into the eye. Adrin (Epinephrin Hydrate). (141) This is the active principle of the su- prarenal glands which is said to be pre- pared according to the method of Prof. J. J. Abel, M. D. Adrin solution is said to be more stable and retain its physiologic proper- ties longer than any other preparation of the suprarenal glands because it is free from hydrochloric acid, the solvent generally used. The following are prepared : Adrin, in powder; it is almost white, stable, and non-hydroscopic. Adrin Tablets, each containing 1/65 grain. For the extemporaneous prepara- tion of the solution. 1 tablet dissolved in 15 minims of sterile water makes a 1 to 1,000 solution of adrin in normal saline solution. Adrin Solution, 1 in 1,000. Adrin Inhalant, containing 1/10% of adrin. Adrin Ointment, containing 1/10% of adrin. Also suppositories of various kinds 1 and other kinds of tablets. Aesculus Cones. (83) Each suppository is stated to contain belladonna, gr. % ; hamamelis, gr. x / 2 ; calomel, gr. I ; "bismuth," gr. 2 ; ich- thyol, gr. 2; combined with the active principle of Aesculus hippocastanum. Used for piles and kindred rectal dis- eases. Agaricin. (Agaric, Agaricinic, Aga- ricic or Laricic Acid.) A resinous acid derived from white agaric. It is a white, almost odorless, tasteless powder, melting at 140° C, slightly soluble in water, in 130 parts cold and 10 parts boiling alcohol ; slight- ly soluble in ether, insoluble in chloro- form. It is used in treatment of night sweats in consumption. Dose: % grain to 1 grain at night in pills. Agathin. (Salicylaldehydemethyl- phenylhydrazine.) It occurs in white or greenish, odor- less, tasteless flakes, melting at 74 C, insoluble in water, but soluble in alco- hol and ether. It is antineuralgic in rheumatic neuralgias, sciatica, etc. Dose : 2 to 8 grains two or three times daily. It should be kept in the dark. Agurin. (Theobromine-Sodmm-Ace- tate.) This is a double salt of sodium ace- tate and theobromine-sodium, and is therefore similar to diuretin. It is a PROPRIETARY AND SYNTHETIC REMEDIES. 665 white, finely crystalline powder, con- taining 60% of theobromine, is hygro- scopic, and freely soluble in water, not readily in cold, but more freely in hot, alcohol. Aqueous solutions gradually split it up into its components. It is precipitated and decomposed by carbon dioxid and by acids; it is also incom- patible with mucilaginous and saccharine liquids. It is used as a diuretic in dropsy of cardiac origin; it is said to be without action on the heart. The dose is 5 to 15 grains, preferably in wafers or capsules. If dispensed in solution, this should be freshly prepared, without sugar or mucilage. Aiken's Tonic Pills. Each is made to contain : Quinine sulfate gr. 1 Reduced iron gr. % Arsenous acid gr. 1/50 Strychnine gr. 1/50 Airol, Airform, Airogen. (Bismuth Oxyiodogallate), (Bismuth Iodo- subgallate.) This is called an odorless substitute for iodoform. # It forms a grayish-green, voluminous, odorless, tasteless powder. It is soluble in alkalies and diluted mineral acids ; in- soluble in water, alcohol, ether and chloroform. Water or moist air (but not light) decomposes it. It is a surgical antiseptic, like iodoform, and anti-gon- orrheal. It contains 20% of iodin. In contact with wounds, iodin is slowly liberated while the bismuth sub- gallate exerts an astringent and siccative action. Airol Paste. This is as follows, according to Prof. Brun's formula : Airol part 1 Glycerin parts 2 Mucilage of acacia, Kaolin. to make a soft paste This paste is to be prepared in a ster- ilized dish, but do not use a metal spot- ula. It is to be kept in well-covered vessels protected from moisture and light. Akaralgia. (G. E. Sodium Salicylate Comp.) (131) This is a granular effervescent salt made according to the formula of Dr. B. K. Rachford of Cincinnati. Each 2 drams is stated to represent Magnesium sulfate gr. 50 Sodium sulfate, dried gr. 30 Sodium salicylate, from oil wintergreen gr. 10 Lithium benzoate gr. 5 Tincture of nux vomica m. 3 This is recommended as a remedy for migraine. Alain's Pomade for the Hair. Ferric oxid 1.5 Mercuric oxid 1.5 Cold cream 57.0 — Analysis by Wittstein. Alapurin. This is a name given to a pure grade of wool fat. Albargin. (Gelatose-Silver.) This contains 15% of silver. It is a coarse, yellow powder freely soluble in cold water ; the solutions remain per- manent and neutral, and are not precipi- tated by solutions of albumin, sodium chlorid, or hydrochloric acid. It is an antiseptic and germicide. It is used as an application or injection in the treat- ment of gonorrhea, chancroids, gonor- rheal ophthalmia, etc. As an irriga- tion or injection it is used in the form of an aqueous solution containing 1/10 to 2/10% of this compound. Albert's Remedy. Contains 29.5% of extractive in which opium alkaloids could be detected, y.g% of potassium iodid, 14.6% of potassium acetate, and 10.3%, of alcohol. It is used as an antirheumatic. — Apoth. Ztg. —Analysis by Dr. H. Weller. Albespeyre's Vesicatory. According to Hager's Praxis, this is made from 1 part each of black pitch and lard, 4 parts each of burgundy pitch and yellow wax, and 6 parts of pow- dered cantharides. The mixture is Gfifi THE STANDARD FORMULARY melted together and is then spread upon taffeta or paper. Alboferin. This is a combination of iron with albumin stated to contain on analysis, albumin, 90.14%; iron, 0.68%; phos- phoric acid, 0.32% ; and mineral matter, 8.86%.. It is a light brown, nearly odor- less powder, and having a slightly salty taste. It is readily soluble in cold water, producing a solution whjch is neutral in reaction and does not coagulate on heat- ing. It is intended as a hematinic. It is marketed in the form of powder and tablets, the latter without and with choc- olate. Albolene. (121) According to manufacturers' state- ments relative to albolene and liquid albolene, these are presumably purified petrolatum and purified liquid petrola- tum respectively. Alcarnose. This is stated to be a predigested food. It is a tough, brown mass containing, ac- cording to the originator, digested albu- min (from meal and vegetables), 23.8% ; extractive matter and salts (from meat), 2.3%; digested carbohy- drates (maltose and dextrin), 67.1%; and salts (sodium chlorid, alkaline phos- phates, carbonates, sulfates and organic salts, alkaline earths, traces of iron), 6.8%. AJdol. Aldol or beta-oxybutyric aldehyde has been suggested for employment as a hyp- notic. It is a thick odorless liquid, mis- cible with two parts of water, and sol- uble in alcohol. When kept for some time it gradually becomes crystalline, be- ing converted into its polymer, paral- dol. Aletris Comp. Elixir. See Elixir Aletris Compound. Aletris Cordial. (173) This is stated to represent 10 grains of aletris, and 30 grains each of helonias and scrophularia. Aleuronate. This is a vegetable albumen prepared by a patented process. It is a yellowish- white tasteless powder. It has been employed for alimentary purposes and to make a diabetic bread, and is also used for surgical purposes. Algidine. (131) This is described as "an inorganic poultice composed of silica, magnesia, alumina and ferrous carbonate, together with the antiseptics eucalyptol, menthol and thymol with an excipient of solu- tion of boroglyceride." It is used for the local, external treatment of all in- flammatory conditions. Alkacetamid. (188) This is described as a compound, alkaline, coal tar derivative. Alkaline Powder. (36) This is stated to contain sodium bicar- bonate 6 parts, and sodium phosphate, exsiccated, 1.12 parts, which are said to be equivalent to 2 parts of sodium bicar- bonate and 1 part of crystallized sodium phosphate. It is used as an acid and mild hepatic stimulant. Alkaline Pancreatin Cordial. (192) This is stated to contain pancreatin, diastase, rhubarb, golden seal, cinna- mon, peppermint, and potassium bicar- bonate. Alkalithia. (105) Each heaping teaspoonful is stated to contain 1 grain of caffeine, 10 grains each of sodium and potassium bicar- bonate and 5 grains of lithium carbon- ate. Alka-Phosphites. (63) This is described as an alkaline syrup of hypophosphites comp., each fluid- ounce of which contains : Potassium hypophosphite gr. V/* Iron hypophosphite gr. l l A Calcium hypophosphite . gr. I Manganese hypophosphite gr. I Quinine hypophosphite gr. 7/16 Strychnine hypophosphite gr t % It is a toniq and stimulant PROPRIETARY AND SYNTHETIC REMEDIES. 66? Alkarhein. (Alkaline Elixir of Rhu- barb Comp. with Pancreatin.) (131) Each fluidounce is stated to contain : Rhubarb gr. 20 Potassium bicarbonate gr. 20 Golden seal (freed from acrid resin) gr. 10 Ceylon cinnamon gr. 10 Pancreatin gr. 8 Also spirit of peppermint and simple elixir. Alkathymol. (159) Each fluidounce is stated to contain : Sodium borate gr. 4 Sodium bicarbonate gr. 8 Sodium chlorid gr. 8 Sodium sulfate gr. 3 Sodium prosphate gr. 1 Menthol gr. J / 2 Thymol gr. % Eucalyptol m. % Oil pinus pumilio m. Vs Glycerin m. 60 Chloretone gr. *4 It also contains about 5% of alcohol. Allingham's Ointment for Hemor- rhoids. Bismuth subnitrate gr. 60 Calomel gr. 40 Morphine gr. 3 Glycerin fl.dr. 2 Petrolatum av.oz. 1 — Columbus Medical Journal. Allyl Tribromid. (Tribromhydrin.) This occurs as a yellowish liquid which acts as a sedative and anodyne in hys- teria, asthma, whooping cough, etc. The dose is 5 drops 2 or 3 times daily, ad- ministered in capsules. Alodonna Pills. (198) Each pill is stated to contain: Aloin gr. 1/4 Extract of belladonna gr. 1/8 Ipecac gr. 1/16 Strychnine gr. 1/60 See Lapactic and Peristaltic Pills. Alpha-Eucaine. See Eucaine. Alphanaphthol. See Naphthol (Alpha). Alphazol. (3) This is described as a concentrated so- lution containing formaldehyde, boro- glyceride, sodium salicylate, thymol, menthol and oil of pine. Alphol. (Alphanaphthol Salicylate.) It corresponds to Betol (which see), the latter being the betanaphthol com- pound, the former the alphanaphthol compound. It is a reddish-white pow- der, soluble in alcohol, ether and fatty oils. It darkens with age and exposure. It is employed in the treatment of ar- ticular rheumatism and gonorrhea in doses of 8 to 15 grains. Alphozone. (187) Chemically this is succinic dioxid or peroxid. It occurs as a white, fluffy powder. It melts at 115 C. and does not decompose until about a temperature of 128 C. is reached. It is therefore not affected by any temperature below that of boiling water, but it should not be subjected to direct heat, such as ex- posure to the rays of the sun or heated steam radiators. When brought into a flame it explodes, but it does not ex- plode on percussion or friction. It dis- solves readily in 60 parts of water and on agitation for a short time will dis- solve in 30 parts. When dissolved in water, it slowly undergoes change, suc- cinic peracid being formed, which is also a powerful germicide. • It is a powerful, non-toxic germicide and antiseptic. It is useful internally in typhoid fever, 4 grains being dissolved in a tumblerful of water, the patient be- ing advised to drink freely of this solu- tion. It may also be used in tonsilitis, leucorrhea and gonorrhea, as a dusting powder in skin diseases of an infectious nature, or as a spray for the nose. The usual proportion in solution as a douche or spray is one part of alphozone to 1,000, 1,500 or 2,000 parts of water. Alsol. This is a name for dried aluminum aceticotartrate. Althaeol Cerate. (160) This is stated to contain althea, ich- thyol, belladonna, eucalyptol-, and a spe- cial base* 668 THE STANDARD FORMULARY Colocynth, fine powder gr. 120 Gamboge, fine powder gr. 120 Oil of anise fl.dr. I Water, to make a mass. Divide into 3-grain pills. Andrews' Tonic-Hematic Pills. Each is made to contain Reduced iron gr. i l / 2 Quinine sulfate gr. 1 Ipecac gr. Va Arsenous acid gr. 1/40 Strychnine sulfate gr. 1/40 Anemic Pills. (129) Each pill is stated to contain Ferrous carb gr. 2 Oxyhemoglobin gr. 3/4 Aloin gr. 1/8 Zinc phosphid gr. 1/20 Strychnine nitrate gr. 1/40 Arsenous acid gr. 1/50 Anemonin. This is the active principle of Ane- mone Pulsatilla. It is in colorless acicu- late crystals, easily soluble in hot alcohol and oils ; very sparingly in water and ether. It is an antispasmodic and seda- tive in asthma, whooping cough, bron- chitis, etc., and anodyne dysmenorrhea, epididymitis, etc. Dose : 34 to 1 grain twice daily, in wafers, pills or powders. The maximum single dose is V/2 grains; the maximum daily dose, 3 grains. Anesthesin. Chemically this is the ethyl ester of paramidobenzoic acid and is closely re- lated to orthoform. It is a white, cry- stalline powder, odorless and tasteless, but producing a sensation of numbness when placed on the tongue. It is almost insoluble in cold, difficultly soluble in hot water, soluble in 6 parts of alcohol, and to the extent of 2 or 3% in fatty oils. In oil solutions it may be sterilized without decomposition, but by prolonged heating with water or by warming with alkalies it is decomposed. It was introduced as a substitute for cocaine and is a local anesthetic similar to orthoform. The anesthetic action is purely local, does not penetrate the mu- cous membrane, and on account of its insolubility it cannot be used hypodermi- cally. It is used in gastralgia, in ulcer and cancer of the stomach, and is recom- mended for anesthetizing wounds, burns, etc. The dose for internal use is 5 to 10 grains 2 or 3 times daily. Externally it may be applied as a dusting powder, pure or diluted, or as an ointment, or in suppositories. Anestheto Obtundent. A dental anesthetic containing about 1 part of cocaine hydrochlorate in 30 of mixture, also carbolic acid, camphor, glycerin, oils of cinnamon and citro- nella, and probably alcohol. — Sadtler. Anesthol. This is a name given to a mixture of 17 parts of ethyl chlorid, 36 parts of chloroform and 47 parts of ether. It is a colorless liquid, having an agreeable odor and a boiling point of 104 F. It has been recommended as an agreeable and relatively safe anesthetic to use by inhalation, being usually without unto- ward after-effects. Anesthyl. (Chloryl.) Ethyl chlorid parts 5 Methyl chlorid parti Angioneurosin. This is a synonym for nitroglycerin. Angier's Petroleum Emulsion. This is advertised to contain in each fluidounce 33 J A% of purified petroleum and 12 grains each of the hypophosphites of lime and soda. It contains no alco- hol. Anhydrosine. (9) This is described as an aseptic clay poultice composed of sterilized bolted clay, anhydrous glycerin, and antiseptics. Anilipyrin. This is a white powder, readily solu- ble in water, prepared by melting togeth- er 188 parts of antipyrin and 135 parts of acetanilid. It is used as an antiseptic PROPRIETARY AND SYNTHETIC REMEDIES. 669 and analgesic" in grip, neuralgia and ar- ticular rheumatism. The dose is 5 to 10 grains 3 or 4 times a day. Anisotheobromine. This is theobromine sodium anisate and contains nearly 48% of theobro- mine. It is less soluble than diuretin and is less easily attacked by the air, and therefore has better keeping quali- ties. Annidalin. This is another name for aristol. Thy- mol iodid, U. S. P., is of the same com- position. Anozol. This is said to be a mixture of thymol and iodoform. Antalgic Saline. (212) This is a granular effervescent salt, each dessertspoonful of which is stated to contain 4 grains each of antipyrin and sodium salicylate. Antemesine. This is a name given to anesthesin put up in gelatin capsules, each contain- ing V/2 grains. It is prescribed in hy- peresthesia of the stomach and in ner- vous dyspepsia. Anthrarobin. A yellowish-brown powder, soluble in 10 parts of glycerin and 10 of cold and 5 of hot alcohol. It is employed medic- inally instead of chrysarobin, in 10 to 20% ointments for psoriasis, herpes, and other skin diseases. Anthrasol. (Odorless Coal Tar.) This is described as coal tar, freed from pitch, pyridine bases, and coloring matter, and mixed with juniper tar and oil of peppermint. It is a thin, mobile, light-yellow oil, which does not stair either skin or clothing. It is miscible with absolute alcohol, acetone, fatty oils, etc. It is an antiseptic and parasiticide. Like ordinary tar it allays irritation of the skin. It is recommended for ec- zema, especially for the after treatment, for all pruriginous affections, in diseases of the hair, as a restorative and for the removal of dandruff. Locally it is used in the form of a 5 to 10% ointment in eczema ; 10% ointment with glycerite of starch and 10% of wool fat in pruritis ; 20 to 30% ointment or paste in lichen ; in combination with sulfur and soap in parasitic skin affections. Antianaemia. Each fluidram is stated to contain iron, 24 grain, iodin, y 2 grain and ar- senic, 1/100 grain. Antiarthritin. This is a remedy for rheumatism and gout; it is said to consist chiefly of salicin. It is a brown powder soluble in alcohol. The dose is 5 to 10 grains. Antibrule. (10) This is stated to be chemically pure "picro-carbolic acid" united with "nas- cent formaldehyde" in a "definite and uniform combination." It has the ap- pearance of a saturated aqueous solution of picric acid. The remedy is advertised as a kera- toplasty, to be used in the treatment of burns and scalds. It may here be stated that a saturated solution of picric acid in water has been proven to be highly successful in the treatment of burns and scalds. Anticongestus. (212) This is stated to be a combination of dehydrated silicate of alumina and magnesia, boric and salicylic acids, iodin, potassium iodid, carbonate of iron, gaultheria, eucalyptus, thymol and pep- permint, incorporated with glycerin. Anticongestus Comp. Described as a mixture of lead water, laudanum, belladonna, and aconite with "anticongestus." Antidiabetin. This is said to be a mixture of saccharin and mannite. It is marketed in three strengths — Nos. 70, 10 and 1 — these numbers indicating the ratio in sweetening power to cane sugar. — Ph. Ztg. 670 THE STANDARD FORMULARY Alterative Tonic Syrup. (181) Each fluidounce is said to represent 4;s THE STANDARD FORMULARY soluble in alcohol. It is incompatible with acids because they decompose it, gradually liberating quinine. It is used for the same purpose as quinine, but is said not to produce any disturbance and is said to be notably free from any tendency to produce cinchonism. Aristol. (Dithymol-Diiodid.) This is a reddish-brown, bulky pow- der, insoluble in water and glycerin, only slightly soluble in alcohol, and freely soluble in ether, chloroform, collodion, and fixed oils and melted fats. It is decomposed by heat and by alkalies. It and its solutions should be kept in dark bottles. It is an antiseptic agent which has largely replaced iodo- form for wounds, ulcers, burns, scalds, diseases of the skin, eye, ear and nose, etc., It is used as a dusting powder, or in the form of ointment with lard, lanolin, etc., or in solution in collo- dion, or in other ways that may sug- gest themselves as suitable. Aristolol. This is the name given a sterilized 10% solution of aristol in oil of sesame. It is said that this preparation never be- comes rancid or decomposed. It is in- tended for various troubles in ophthaol- mic practice, such as accidental burn- ing of the cornea, etc., with caustic alka- lies. Armenian Pills. Balsam of copaiba parts 14 Magnesia, calcined light. . .parts 2 Cubeb, powder parts 7 Armenian bole, powder parts 7 Heat the copaiba until it acquires the consistence of a plaster, that is, until most of the volatile oil has been dis- sipated, then mix it with the magnesia and set it aside that the mass may set. Next add the powdered cubeb and Armenian bole, and mix intimately. Make the mass into pills of 8 grain each and roll them in Armenian bole. — Schacht. Arnold's (Seth) Anti-Bilious Pills. These are stated by the manufac- turers to contain aloes, jalap, "podoph.," extract of belladonna, croton oil and oleoresin of ginger. Arnold's (Seth) Cough Killer. The manufacturers state that it con- tains squill, ipecac, wild cherry, nitre, morphine and chloroform. The amount of morphine in the form or sulfate is % grain, of chloroform, V3 minim, to the fluidounce. It also con- tains 15% of alcohol. Arolax. (Aromatic Laxative.) (16) This is stated to be an agreeable laxative, cathartic and stomachic tonic for infants, children and adults, each fluidram containing cascarin 1 grain, succus rhei (Sinense) 5 drops, sodium phosphate 10 grains, and aromatic cord- ial, q. s. The circular issued by the manufac- turers mentions the Sinense rhubarb or rheum officinale, which is the Chin- ese or East India rhubarb. Reference is also made to combining cascara sagrada with rhubarb. The bottle is directed to be shaken before use. Arophene. This contains about i J A% of cocaine hydrochlorid, also carbolic acid, chloral, glycerin, and oil of rose. It is used as a dental anesthetic. — Sadtler. Arrhenal. (Disodium Methylarsen- ate.) This is in colorless crystals, efflores- cent, of alkaline taste, and readily sol- uble in water but sparingly in alcohol. It is an arsenic compound which is con- sidered therapeutically an improvement over sodium cacodylate. It is used as a substitute for the inorganic compounds of arsenic in tuberculosis, malaria, skin diseases, etc. The dose is Vz to 1 grain. Arsenauro. (Solution of Bromids of Gold and Arsenic: Barclay.) This, the manufacturers claim, con- tains, in every 10 drops, 1/32 grain of gold bromid and 1/32 grain of arsenic bromid. PROPRIETARY AND SYNTHETIC REMEDIES. 679 Arsenhemol. (Arsenated Hemol.) It is a brown powder, compound- of hemol with i% of arsenous oxid. This is an alternative and hematinic, a substitute for arcenic without un- toward effect on stomach. Dose: i]/ 2 grains, in pills, 3 times daily, increased every 4th day by V/2 grains, until 15 grains are taken per day. Arsycodile. (Sodium Cacodylate.) This is marketed in pills, supposi- tories, and solutions for hypodermic use and for rectal injection. It is highly recommended for tuberculosis and is also used for dermatoses, diabetes, can- cer of the stomach, goitre, malarial fevers and neurasthenia. The dose is Vz to Yz grain. Arthrosia Pills. (212) These are stated to contain salicylic acid, extracts of colchicum and poke, podophyllin, quinine sulfate, and capsi- cum, quantities not stated. Artol. (76) This is described as a bland non- irritating oil derived from petroleum. It is used as a vehicle for medicated sprays. Artoline. (76) This is described as a purified, semi- solid, white emollient from petroleum, to be used as a vehicle for ointments. Asaprol. (Calcium Betanaphtholal- phamonosulfonate — Abrastol.) A whitish, odorless powder, decom- posing near 50 C. (i22°F.) It is sol- uble in 1 part of water, 2 of alcohol, but insoluble in ether. It is an antiseptic, antirheumatic, antithermic, etc., in diphtheria, rheuma- tism, gout, typhoid fever, influenza, etc. It is used as an antiseptic in 5% solu- tion. Dose: 15 to 60 grains daily. Asepsin. See Gaultherine. Aseptic or Aseptinic Acid. An aqueous solution of 5 parts of boric acid in 1,000 parts of hydrogen peroxid (5%), with or without 3 parts of salicylic acid. — Thomas. Asepsin. See Antisepsin. Aseptin. This is a meat and milk preservative said to be composed of : Borax parts 2 Alum part 1 —Nat. Dr. Aseptine Powder. (154) This is described as being composed of "benzo-boric acid," salol, aluminum and zinc sulfates, phenic and thymic acids, menthol, eucalyptol, and methyl salicylate. Aseptol. This is a ZZYs% solution of orthosulfo- carbolic acid. It is a dark syrupy liquid, miscible with water, alcohol and gly- cerin. The odor is similar to carbolic acid in place of which it is used in cys- titis, skin diseases and diphtheria. It is said to be less irritating than carbolic acid. It is used in solutions of I to 10%. Aseptolin-Edson. This is stated to be a solution of 0.02 Gm. pilocarpine carbolate in 100 Cc. 2*A% carbolic acid. It is an anti- tubercular and antiperiodic which is used only hypodermically. In phthisis 5 Cc. is used once a day, the dose being in- creased daily by 0.5 Cc. until 7 Cc. are reached. In malaria 6 Cc. are injected over the abdomen on each side of med- ian line twice the first day, and for 6 days following half this dose is injected daily, and for 2 weeks thereafter every third day. Aspirin. (Acetylsalicylic Acid.) This is a white powder, of an agree- able, slightly acid taste. It is soluble in 100 parts water but readily in alco- hol and ether. It is decomposed in solu- tion and is incompatible with alkalie?. THE STANDARD FORMULARY It is best preserved by itself in powders or capsules. It is used as a substitute for salicylic acid and salicylates in rheumatism, fevers, etc. The dose is 15 grains 3 or 4 times daily. Astringent and Antiseptic Comp. (97) This is stated to be a combination of thymol, menthol, eucalyptol, cinnamic, phenic and boric acids, with potassa dium. It is an impalpable powder for making solutions for the treatment of diseased mucous surfaces. Athenstsedt's Comp. Tr. Iron. This is a German proprietary remedy. Dieterich says the following makes a similar preparation : Iron saccharate, 10% g. 22 Distilled water g. 57° Simple syrup g. 240 Alcohol .' g. 165 Citric acid g. 0.20 Tincture of orange peel g. 30 Aromatic tincture g. 0.75 Tincture of cinnamon g. 0.75 Tincture of vanilla g. 0.75 Acetic ether drops 2 Dissolve the iron saccaharate in the water, add the other ingredients, and filter if necessary. Atoxyl. (Metaarsenic Anilid.) This is a white, odorless, tasteless, crystalline powder, soluble in water. The dose per diem 1 to 3 grains adminis- tered subcutaneously. It contains 38% of arsenic but is much less poisonous than other arsenic compounds. It is used for the same purpose as other arsenic compounds. Atrabilin. This is described as a yellow, opales- cent, liquid extract of the suprarenal capsules. It is used for functional hyperemia and other affections of the eye in this mixture: Atrabilin, 4; boric acid, 1 ; distilled water, 20. Aubergier's Paste of Lactucarium. The following formula for a lactuca- rium paste, presumably Aubergier's formula, is taken from Bouchardat's Formulary : Jujube paste. gm. 100 Alcoholic extract of lactuca- rium gm. 1 Tincture of tolu gm. 2 In making the original, undoubtedly the paste prepared from jujube fruit is used in the above. Aubergier's Syrup. This is stated to contain 1/10% of extract of Aubergier's lactucarium and 6/100 of a milligram per gram. Auritme. (63) Each ten drops are stated to contain 1/32 grain each of the bromids of gold and arsenic bromids. Ayer's (J. C.) Cherry Pectoral. According to the revised formula each fluidounce represents Wild cherry gr. 6 Grindelia robusta gr. 6 White pine gr. 4 Senega gr. 4 Bloodroot gr. 2 Rio ipecac gr. 2 Citric acid gr. 2 Terpin hydrate gr. 1 Glycerin dr. 4 Water, to make fl.oz. 1 It is stated to be non-alcoholic. Ayer's (J. C.) Hair Vigor. This is stated to contain alcohol, 15% ; cantharides, sodium chlorid, sage, qui- nine, sulfur, glycerin, water, and per- fume. Ayer's Malaria and Ague Cure. Each fluidounce is stated to represent Quinia gr. 8 Cinnamon gr. 8- Jamaica ginger gr. 8 Cloves gr. 4 Peppermint gr. 8 Orange peel gr. 12 Alcohol, to each fl.dr m. 12^2 Glycerin, syrup and water. Ayer's Pills. Each one is stated to contain Jalap gr. J / 3 Ginger gr. l / 3 Aloes gr. % Colocynth pulp gr. % Podophyllin gr. 1/10 Gamboge gr. 1/20 Oil of peppermint ..gr. 1/50 Oil of spearmint gr. 1/100 PROPRIETARY AND SYNTHETIC REMEDIES. 681 Ayer's (J. C.) Sarsaparilla. According to the manufacturers, each fluidou'nce represents Sarsaparilla root gr. 10 Yellow dock root gr. 8 Licorice root gr. 8 Red cinchona bark gr. 6 Buckthorn bark gr. 4 Stillingia root gr. 4 Burdock root gr. 3 Senna leaves gr. 2 Black cohosh root gr. 2 Poke root gr. 1 Potassium iodid gr. 4 Glycerin dr. s l / 2 Flavoring : Oil sassafras, oil win- tergreen. Water, to make fl.oz. 1 It is stated to be non-alcoholic. Azoa. (Rat Virus.) (159) This is a biological product, a disease- producing virus for the destruction of rats, mice and field animals; it infects them with a disease that kills in from 8 to 14 days. This disease is readily communicated to other animals of the same kind, but is harmless to human beings as well as to such animals as dogs, cats, fowl, etc. It is prepared in powder form and is to be mixed with oatmeal. Bana— Diastase. (100) This is described as "a starch-convert- ing ferment of vegetable origin, capable of converting, under favorable condi- tions, 150 times its weight of starch into maltose and sugar." Barclay & Harvey's Antibilious Pills. The principal ingredient is compound extract of colocynth. — H. Barr's Dental Anesthetic. This is an alcoholic solution of oils of clove and peppermint. — Sadtler. BarralFs Antiasthmatic Cigarettes. These consist of absorbent paper rolled up and satuated with potassium nitrate and infusion of herbs similar to Espic Cigarettes. — H. Barry's Tricopherous. According to N. I., a substantially similar preparation is made as follows : Castor oil fl.oz. 1 Alcohol fl.oz. 5 Oil of lavender drops 5 Oil of bergamot drops 2 Color, pink with alkanet root. According to statement on the pack- age, it contains 81% of alcohol. Bartholow's Elixir Gentian with Tincture Chlorid of Iron. (133) Each fluid-dram is stated to contain 4 grains of gentian and 4 grains of cit- rochlorid of iron. Barutin. (Barium Theobromine and Sodium Salicylate.) This is a white, odorless, crystalline powder, of a sweetish taste, soluble in water. It contains 25^% of theobro- mine and is used as a diuretic in doses of 5 to 10 grains in sweetened solution, avoiding acid syrups. Basicin. This is a compound of quinine hydro- chlorid and caffeine, containing 65% of the former and 35% of the latter. It is a white crystalline powder soluble in 1 part of water. It is given for mouth and subcutaneously in doses of 3 to 8 grains for migraine, influenza, rheuma- tism, etc. Basicin Oil. This is a mixture of 2 parts of basicin, 15 parts of chloroform, 5 of alchohol, and 18 of olive oil. It is used as an embrocation to assist the action of the basicin administered simultaneously instead of the basicin when the latter is not well borne by the stomach. Basol. This is a disinfectant similar to liquor cresoli compositus U. S. P. ; it is said to contain 50% of cresol. Bassorin Paste. This is a new ointment vehicle. It is a smooth, homogeneous paste, resem- bling petroleum in consistency. It dries on the skin and can be removed readily by washing with water. Bates' Salve. Beeswax av.oz. 2 Amber resin... av.oz. 3 Linseed oil fl.oz. 10 Red lead av.oz. 4 Boil with constant stirring until the whole is dark brown. — B & C. Dr. 682 THE STANDARD FORMULARY Bateman's Lotion. Corrosive sublimate gr. 2 Compound spirit of lavender. fl.oz. I Water fl.oz. 4 Dissolve the corrosive sublimate in the spirit, and add the water. It is used in cutaneous eruptions. — Cooley. Battley's Sedative. (Battley's Solu- tion of Opium.) This is an extinct English patent preparation. See Solution of Opium, Sedative of the N. F. Baume Analgesique, Bengue's. This is stated to contain menthol, methyl salicylate and lanolin. It is in the form of an ointment, put up in collapsible tubes. Baunscheidt Oil. Baunscheidt was a German charlatan who claimed to cure rheumatic and other diseases by means of what he called a "lebens-wecker," i. e., "awakener" or "revulseur." This consists of a num- ber of sharp-pointed needles set in a bed of hard rubber. By means of a spiral-spring arrangement these needles are driven into the skin over the seat of pain, not deep enough to draw blood, while into the wounds produced is rubbed the "Baunscheidt oil." This is an irritating substance and produces papular eruptions similar to those pro- duced by croton oil. The effect is that of a powerful counter-irritant. In medi- cine this treatment is known as acu- puncture. Formulas for the oil are given by Hager as follows : I. Euphorbium, powder dr. 3 Cantharides, powder gr. no Olive oil fl.oz. 8 Macerate for 7 days and filter. II. Euphorbium, powder gr. 140 Mezereum, cut fine gr. 280 Cantharides, powder gr. 30 Alcohol, absolute fl.dr. 9 Ether fl.oz. V/ 2 Olive oil fl.oz. 8 Mix the two powders, alcohol and ether, in a closed vessel, macerate for 7 days, agitating occasionally; then add the oil, marcerate again for 7 days, strain, heat the colature gently so as to expel the ether, and filter. Bechol. See Elixir Pinus Compositus. Becker's Eye Balsam. According to Parrish's Pharmacy this salve resembles it : Calamine gr. 90 Tutty gr. 90 Red oxid of mercury gr. 6 Camphor gr. 60 Sweet almond oil fl.dr. 1 White wax av.oz. 1 l / 2 Butter, fresh (unsalted) . .av.oz. 8 Beckwith's Hog Cholera Remedy. This, according to a patent specifi- cation, consists of equal parts of man- drake, sulfur, sodium bicarbonate, charred coffee and potassium chlorate. Beecham's Pills. An approximate formula is the fol- lowing : Aloes gr. 480 Rhubarb gr. 90 Sodium sulfate gr. 24 Saffron, true gr. 24 Make into 3 grain pills. — Ind. Ph. Bejean's Gout Specific. According to an analysis by Hahn and Holfert, this consists of extract of gentian, 5 parts, potassium iodid and sodium salicylate, each 4 parts, water. 80 parts, alcohol, 20 parts, and oil of wintergreen, enough for flavoring. — Apoth. Ztg. Bell's Syrup of Codeine. (20) This is stated to contain V 6 grain of codeine phosphate ; 24 grain of terpin hydrate; y 2 grain of eucalyptus extract and y grain of ipecac to the dram, in a vehicle containing a little sugar. Belloc's Charcoal Lozenges. According to Hager each one con- tains 1 grain of wood charcoal. Benesol. (110) This is local anesthetic for dental use. It is said to be sterile solution of beta- PROPRIETARY AND SYNTHETIC REMEDIES. 683 eucaine, cocaine hydrochlorid, carbolic acid, menthol, eucalyptol and amyl nitrite in distilled water. It is used hypoder- mically. Benzacetin. (Acetoamidomethyl-sa- licylic aeid.) This is in colorless crystals, which are almost insoluble in water, freely soluble in alcohol. It is recommended as an antineural- gic in doses of 8 to 15 grains. Benzanilid. (Phenylbenzamid.) This is a white powder, soluble in 58 parts of cold and 7 parts of hot alcohol, but is almost insoluble in water. It is used as a children's antipyretic, that is, it is a mild antipyretic especially suited for children. Dose : 2 to 10 grains for children ranging in age from 1 to 12 years. Benzartol. (76) This is a combination of the antisep- tic and aromatic principles of gum benzoin with artol (which see). Benzoglycine. (195) This is described as compounded from the antiseptic constituents of thyme, eu- calyptus, methyl salicylate and Chinese peppermint, each fluidram also contain- ing the equivalent of ij^ grains of pure boracic acid combined with benzoic acid. Benzoinol. It is said by the proprietors to be "benzoic balsam," dissolved in a spe- cially prepared, pure petroleum oil. Benzonaphthol. (Betanaphthol Ben- zoate.) This is a whitish powder, soluble in chloroform and alcohol, almost insol- uble in water. It darkens with age. It is used as an intestinal antiseptic in diarrhea and typhoid fever, like betol, the dose being 3 to 8 grains sev- eral times daily. It has been recommended for ex- ternal use in the form of a 3 to 10% ointment for psoriasis, eczema, scabies, etc. Benzosol. (Benzoyl-Guaiacol — Guaia- col Benzoate.) This is a colorless, crystalline powder, inodorous, tasteless, insoluble in water, readily soluble in alcohol. It contains 54% of guaiacol. It is used as an anti- septic in the treatment of phthisis, ty- phoid fever, diabetes, etc. It is said to be non-irritating. It is used as a sub- stitute for guaiacol and creosote. Dose: 4 grains, increased to 12 grains, three times daily. Benzosalin. This is the methyl ester of benzoyl- salicylic acid is therefore an analog of aspirin acid like it is used for rheu- matic and neuralgic affections in doses of 3 to 15 grains several times a day. It is in white, almost tasteless, needle- shaped crystals, soluble in alcohol, in- soluble in water. Benzoyl Peroxid. This is made by the action of sodium peroxid on benzoyl chlorid. It is a white crystalline substance, sparingly soluble in water, readily soluble in alcohol, soluble to the extent of 2 or 3% in oils. It is used to some extent as an appli- cation to burns as it deadens the pain and appears to promote healing. Benzozone. This is now known as Acetozone, which see. Berthe's Syrup of Codeine. According to Hager, this is a solution of 1 g. of codeine in 125 g. of simple syrup. Beta-Eucaine. See Eucaine. Betanaphthol. See Naphthol (Beta). Betanaphthol Benzoate. See Benzonaphthol. Betanaphthol-Bismuth. See Orphol. Betol. (Naphthalol, Naphtosalol, Sali- naphtol, Betanaphtol Salicylate.) This is a white, inodorous, insipid powder, melting at 95 ° C. It is soluble 684 THE STANDARD FORMULARY in 3 parts of boiling alcohol, also in ether, but almost insoluble in water or glycerin. It is an internal antiseptic, antizymotic, etc., in putrid processes of the intestinal tract, cystic catarrhs, etc., being used like salol. Like salol it is split up by the alkaline intestinal fluids. It is also used as an antirheumatic. Dose : 5 to 10 grains 4 times daily. Betul-Ol. (8) On the label this is described as "mentho-menthyl-oleo-salicylate chemi- cally combined with 2% of chloral." On a circular it is stated to be a 2% solution of menthol in a methyl ester of the salicylic radical. It is also described as a compound methyl salicylate of Be- tula lenta. Biodal. Chemically this is moniodobismuth- methylene dicresotinate. It is used as a surgical antiseptic as a dusting powder for wounds. Bioferrin. (103) This is stated to be prepared as fol- lows: The blood of healthy oxen is freshly drawn and is treated with ether, after removing the fibrin. The ether dissolves a certain part of the blood, and serum which separates contains the haemoglobin. This is then freed from any ether that may have remained by means of a current of sterilized air, and is mixed with 20% of glycerin and 4% of aromatic tincture. No heat whatever is used in this process; on the contrary, the temperature is lowered artificially during manufacture. The preparation is said to contain the constituents of the blood, especially oxyhemoglobin, in an unaltered state, and occurs as a blood- red fluid of pleasant taste and odor. Bioforin. This is described as a granulated powder consisting of calcium glycero- phosphate, 50, extract of kola, 20, ex- tract of cinchona, 10, extract of coca, 5, chocolate, flavored with vanilla, 40, su- gar, 875. Biogen. This is described by the makers as containing 2>Z l A% of magnesium dioxid, Mg 2 , a new chemical compound dis- covered by Dr. Elias of Berlin; it is stated to yield a high percentage of nas- cent oxygen in the economy. It is an odorless, tasteless, insoluble white pow- der, non-irritant and non-astringent. It is recommended in infantile gastric and intestinal troubles, in anemia, pneumo- nia, asthma, etc. The dose is 5 to 15 grains. Bioplasm. (24) This is described by the makers as a "tissue food." It is a light gray, sweet powder, soluble in water. The dose is 5 to 15 grains, several times a day, Bismal. (Bismuth Methylenedigal- late.) This is a gray-blue, bulky powder, which is soluble in alkalies, but insolu- ble in water or in the gastric juice. It is used as an internal astringent, espe- cially in diarrheas not benefited by opi- ates, such as chronic diarrheas. Dose: 2 to 5 gr. every 3 hours or several times daily, in wafers or pow- der. Bismon. (Colloidal Bismuth Oxid.) This is product by the action of bis- muth salts upon an alkaline aqueous so- lution of protalbin or sodium lysalbin- ate. It contains 20% of metallic bis- muth and is soluble in both hot and cold water. It is non-toxic and is borne by delicate stomachs in 5 or 10% solu- tions. Bismopepsin Tablets. (138) These are stated to contain bismuth subnitrate, pepsin and ginger in com- bination with pleasant aromatics. It is recommended for many gastric com- plaints. Bismutan. This is a combination of bismuth, re- sorcin and tannin. It is used a^ an an- tidiarrhea remedy in doses of 8 to 15 grains. PROPRIETARY AND SYNTHETIC REMEDIES. 685 Bismuth Agaricinate. This is a white, tasteless powder, in- soluble in water, employed in the night sweats o£ phthisis, intestinal catarrh, etc., in doses of 5 to 15 grains. Bismuth and Hydrastia. See Blenol. Bismuth Betanapthol. See Orphol. Bismuth Beta-Naphthol Comp. (141) This is put up in tablets, each one of which contains Bismuth betanaphthol gr. 3 Guaiacol gr. Va Thvmol gr. 7& Eucalyptol gr. Vs Bismuth Cinnamate. See Hetoform. Bismuth Formic-Iodid. (141) This is a yellowish powder, insoluble in water. It is stated to be composed of formaldehyde, gelatin, boric acid, bis- muth subgallate, alum, iodin, and ace- tanilid, containing i3 r A% of the latter. It is used as an antiseptic dusting pow- der. Bismuth Formic-Iodid Ointment. This is stated to be composed of 60 grains of bismuth formic-iodid, 20 grains of peru balsam, and 1 ounce of benzoinated petrolatum. Bismuth Oxyiodopyrogallate. This is a fine, amorphous, yellowish- red powder, insoluble in water and the usual solvents, and permanent in air and light. It is recommended as a pow- erful surgical antiseptic, not so readily decomposed by water as the other bis- muth preparations. It has been used as an application to wounds to promote cicatrization. Bismuth Oxyiodotannate. See Ibit. Bismuth Phosphate. See Bisol. Bismuth Pyrogallate. See Helcosol. Bismuth Salicylate. There are two salicylates of bismuth, one being basic, the other acid. The former should always be used when "bismuth salicylate" is specified. It con- tains 65% bismuth oxid and 35% salicy- lic acid. It is a whitish, odorless, taste- less, permanent, microcrystalline pow- der which is soluble in acids and alkalies with decomposition ; insoluble in water, alcohol and ether. It is recommended in gastric and in- testinal affections in doses of 5 to 15 grains, administered several times daily ; in typhoid fever, in 10 to 20 grain doses, repeated every hour for about 10 hours. The good results are attributable to the fact that the combination is readily borne by the stomach. Bismuth Subgallate. See Dermatol. Bismuth Subiodid or Oxyiodid. This is a brownish-red, amorphous, inodorous, insoluble powder. It is used as an external and internal antiseptic in suppurating wounds, ulcers, gonorrhea, etc., gastric ulcerations, typhoid fever, etc. Dose : 5 to 10 gr. daily. Bismutal or Bismutol. This is said to be a mixture of solu- ble bismuth phosphate and sodium sali- cylate. Bismuthal. (142) This is the name given by this firm to a "lac bismuthi cum pepsino." Bismutose. (Bismuth Proteinate.) This is a combination of bismuth with albumen containing 22% of metallic bis- muth. It is prepared by treating a solu- tion of the albumen of eggs with a pure solution of bismuth nitrate in a solution of sodium chlorid. The coagulated com- pound is washed, dried and powdered. It is a greenish-yellow, odorless, taste- less powder, insoluble in water and alco- hol, but soluble in solutions of the alka- lies. It is of value as an intestinal as- tringent in the diarrheas of children. 686 THE STANDARD FORMULARY The dose is 15 grains for very young infants and upwards, every hour. Bisol (Bismuth Phosphate). This is a white powder containing about 20% of bismuth oxid, besides j some bismuth phosphate. It is soluble in 3 parts of water, heat, alkalies and acids rendering the solution turbid. It is used as an intestinal antiseptic and astringent in acute gastric or intes- tinal catarrh, etc. Dose : 8 grains several times daily. Blackburn's Casca Royal Pills. These are stated to contain castor oil, cascara, wild lemon, black cherry root, sulfur, mix vomica, ginger, and pepsin. Blair's Gout and Rheumatic Pills. A correspondent of the N. I. states that they are composed of acetic extract of colchicum and extract of henbane (proportions not given.) Blancard's Pills. The following formula for similar pills is taken from Bouchardat's Form- ulary : Iodin gr. 63 Reduced iron gr. 31 Distilled water fl.dr. 2 Honey gr. 75 Absorbent powder gr. 125 Make into 100 pills and coat with an ethereal tincture of tolu. The pills of iron iodid of the U. S. P. are practically the same. Blancoline. (01. Paraffin. Pur.) (115) This occurs in the solid and liquid forms. The solid is described as a perfectly white, odorless ointment con- forming to U. S. P. requirements for pure petrolatum. The liquid is colorless and odorless. Blandine Comp. (141) Each fluidounce is stated to contam Menthol gr. V 5 Thymol gr. M> Eucalyptol gr. % Camphor gr. \Vz Oil of wintergreen m. 1Y2 Hydrastine hydrochlorid gr.l/40 In combination with "blandine," a neu- tral, colorless mineral oil. Blatta Insect Powder. These formulas have been given fo? it: T. Persian insect powder av.oz. 8 Borax av.oz. 8 Sulfur av.oz. 4 Oil of eucalyptus fl.dr. 2 II. Persian insect powder av.oz. 8 Borax av.oz. 8 Sulfur av.oz. 4 Eucalyptus leaves av.oz. 4 Mix and reduce to fine powder. Blaud's Compound. (108) Tablets each said to contain : Blaud's mass gr. 5 Corrosive sublimate gr. 1/80 Strychnine sulfate gr. 1/60 Arsenous acid gr. 1/50 Blennostasine. (121) This occurs in the form of small, yellowish, odorless, very bitter crystals; it is insoluble. It is said to be "a bromin derivative of cinchonidine, yield- ing, on analysis, results agreeing with the empirical formula Ci9H 24 N 2 OBr 2 ." The formula for cinchonidin being C10H22N2O, the formula given would correspond to G 9 H 22 N 2 (HBr) 2 , or, in other words, the substance may be a hydrobromate (bromid) of cinchon- idine. It is used as a remedy for la grippe, colds, and hay fever. The dose is 1 to 4 grains every hour. Blenol. (Solution Bismuth and Hy- drastia). (131) This is described as a sodution of the double citrate of bismuth and hydrastine (the white alkaloid of golden seal.) Blucaloids. (187) These are capsules of methylene blue and Australian eucalyptus oil, and are intended to be used as an antimalarial. Blush of Roses. This is a copy of the formula sent out a few years ago: Epsom salt oz. 16 Water oz. 48 Alcohol oz. 8 PROPRIETARY AND SYNTHETIC REMEDIES. 687 Corrosive sublimate gr. 5 Ammonia drops 20 Oil of rose sufficient Dissolve the salt in the water, the corrosive sublimate and oil in the alco- hol, mix the two solutions, filter and add the ammonia. This was recommended as an applica- tion to the face instead of face pow- der. Blutan. This is a carbonate solution of pep- tonized acid-albumin-iron-manganese, free from alcohol and containing 0.6% of iron and 0.1% of manganese. It is also put up with iodin and bromin, the former containing 1/10% of iodin, the latter 1/10% of bromin. Boerhave's Anti-Asthmatic Elixir. Licorice root gr. 180 Calamus gr. 120 Elecampane gr. 120 Orris root gr. 60 Aniseed gr. 60 Canada snake root gr. 30 Camphor gr. 10 Alcohol fl.oz. 16 Some formularies give diluted alco- hol as the menstruum. — Bouchardat's Fomulary. Bonjean's Elixir de Sante. Tincture of bitter orange.... g. 25 Oil-sugar of anise g. 10 Oil-sugar of caraway g. 10 Oil-sugar of peppermint g. 10 Spirit of ether g. 15 Infusion of tea g. 100 Simple svrup g. 150 — H. Boonekamp's Bitters. Orange berries g. 100 Gentian g. 60 Orange peel g. 30 Cascarilla g. 30 Cinnamon g. 25 Curcuma g. 15 Clove g. 15 Rhubarb g. 7-5 Alcohol g. 750 Water g. 1650 Sugar g. 250 Oil of anise drops 40 Mix, macerate for several days, ex- press and filter. — H. Boracetanile. (221) This is an antiseptic powder, com- posed, according to the manufacturers, of: Acetanilid part 1 Boric acid parts 3 Boral. (Aluminum Boro-tartrate.) This is in white crystals, of sweet, astringent taste, and soluble in water. It is used as a disinfectant and as- tringent in inflammations of the nose and throat chiefly. It is applied in sub- stance or in solution, with addition of glycerin. Boralid. This is said to be a mixture of equal parts of acetanilid and boric acid. It is used as a dusting powder. Boraline. (28) This is stated to be composed of boric acid, alum and menthol with "antisep- tic acids of the coal tar series.' Borcherdt's Malt Extract with Yerba Santa Comp. Each teaspoonful contains F. E. yerba santa gr. 1 Ammonium chlorid gr. 1 Heroin gr. 1/48 Bordet's Hair Tonic. Carbolic acid fl.dr. 2 Tincture of cardamom fl.dr. 2 Tincture of nux vomica. .. .fl.oz. 1 Comp. tinct. cinchona fl.dr. 4 Cologne water fl.dr. 4' Cocoanut oil, to make fl.oz. 16 —A. D. Borhaver's Vegetable Stomach Pre- servative. According to Hager, this is composed of 140 g. of alcohol, 76 g. of sugar, 1 g. of aloes, 23 g. of extractive matter from cinnamon, galangal, zedoary, cloves, angelica, clove, gentian and quas- sia, and 200 g. of water. Borine. This is stated to be composed of the active constituents of styrax benzoin, gaultheria procumbens, spirsea ulmaria, solidago odora, hamamelis virginica, the stearoptens of thymus serpyllum, euca- lyptus globulus, and mentha arvensis, with boracic acid. 688 THE STANDARD FORMULARY Bornyval. (Borneol Isovalerianate.) (172) This is the isovalerianic ester of borneol. It is a colorless liquid of aro- matic, valerian-like odor and a faint taste of valerian. It is said to fully represent the active constituents of valerian root. It is prescribed in ner- vous disorders in 5 grain capsules, 1 to be taken after meals. Boro-Chloretone. (159) This is a mixture of 1 part of chlore- tone and 3 parts of boric acid. It is an antiseptic arid is applied as a dusting powder to wounds, burns, scalds, ulcers, insect stings, etc. It is a local anesthetic so that it allays pain when applied to a wound. Boro-Fluorine. See Stafford's Boro-Fluorine. Boroformalin. (Boroformol.) (67) An antiseptic liquid, stated to contain "borosalicylic-glycerole," "benzoresorci- nol," menthol, thymol, eucalyptol and formalin. Borol. (159) Each fluidounce is stated to represent Sodium borate gr. 12 Sodium bicarbonate gr. 12 Sodium benzoate gr. 5 Menthol gr. V& Eucalyptol gr. x k Thymol gr. 5/16 Glycerin m. 90 Oil of pinus pumilio q. s. This should not be confounded with another preparation of the same name which is a melted mixture of boric acid and sodium or potassium bisulfate. Borolyptol. (Formolyptol.) (158) An antiseptic liquid stated to con- tain, according to the manufacturer, 5% of "aceto-boro-glyceride," 0.1% of formaldehyde, and pinus pumilio, euca- lyptus, myrrh, styrax and benzoin. It contains 8% of alcohol. Boromenthol. Boromenthol Bengue Pills are stated to be composed of menthol, cocaine hy- drochlorid and sodium borate. Waterbury's Boro-Menthol is an anti- septic liquid, each fluidram of which is stated to contain 2 grains of "benzo- boracic acid" and the antiseptic princi- ples of thyme, eucalyptus, baptisia, gaul- theria and mentha arvensis. Boro-Naphthol Soap. (131) This is described as combining the antiseptic gaultherine, boroglyceride and pure betanaphthol with a bland non- irritating soap. Borophenol. This is prepared by allowing dried borax to absorb carbolic acid. Borosal. This is a colorless liquid containing, according to various analses, alumin- ium tartrate, boric acid, salicylic acid, and free tartaric acid in aqueous solu- tion. — Coblentz. Borosalyl. Boric acid , .parts 25 Salicylic acid parts 32 Water sufficient Triturate the acids with a small quan- tity of water to a smooth paste, dry and reduce to powder. Boro-Salicylate. A similar product is made by trit- urating together 5 parts of sodium salicylate with 4 of boric acid and a small amount of water, drying and pow- dering. The "Boss." (Prescription 49.) (187) An anti-gonorrheal remedy, an in- jection and pills being put up in one package. A fluidounce of the injection is stated to consist of Hydrastine (white alkaloid) . .gr. \ x k Zinc sulfate gr. 1 Boric acid gr. 5 Carbolic acid gr. Va The pills are stated to contain each Copaiba gr. 1V2 Oleoresin of cubeb gr. 1 Ferrous sulfate, exsiccated. . .gr. % Carbolic acid gr. Vz Extract of belladonna gr. Vs Extract of aconite gr. i/io Oil of peppermint m. 1/10 PROPRIETARY AND SYNTHETIC REMEDIES. 689 Dentifrice. (Eau de Botot's Eau Botot.) Anise seed g Clove g. Cassia bark g, Cochineal g Vanilla g Alcohol g Rose water g Tincture of ambergris g Oil of peppermint g ioo 25 25 5 1-5 1000 300 1-5 10 — H. Boules de Mars. (Boules de Nancy.) According to Hager, these are pre- pared by heating 100 parts of tartrate of iron and potassium with 20 parts of distilled water and 1 part of powdered gum arabic on a water bath until the mass may be formed into balls on cool- ing. This is then made into balls weigh- ing 35 to 36 g. which are to be dried in a moderately warm place when they should weigh about 30 g. They may then be coated with mucilage of acacia to which a small amount of tincture of nutgall has been added to impart a shiny black appearance. Bourdalle's Ethyl-Methyl Chlorid Mixture. This is used for producing local an- esthesia, and is said to be a mixture of chemically pure ethyl chlorid and methyl oxid, proportions not being given. Bovinine. The manufacturers published this formula : Defebrinated bullock's blood 65% Desiccated egg albumen 19% Bourbon whiskey 10% Pure glycerin 5% Boracic acid 1% Boyveau-Laffecteur Boot. According to Hager, this is similar to compound syrup of sarsaparilla. Bracelin Remedy for Diphtheria. The remedy consists essentially of chlorin deprived of its suffocating, irri- tating qualities by an emollient correc- tive. The value of the "corrective" is not so much due to the agents used as to the process of manufacture in making the combination. Properly made, the results will be satisfactory, if improperly combined the results will be disappointing. This is the result of my repeated trials and clinical experi- ments carried on during a period of over two years. Two liquids are used, which are for convenience named "Bracelin Chlorin Bactericide," "No. One" and "No. Two." "B. C. B. No. 1" is set free by the corrected chlorin in "B. C. B. No. 2." "B. C. B. No. 2" is added to "B. C. B. No. 1" in the pro- portion of 1 to 5 parts slightly warmed and the vapor inhaled as directed. Some diseases, such as diphtheria and pneu- monia, require its use once each hour, others but 4 or 5 times a day. I am now prepared to give my formula to the profession for trial in the treatment of diphtheria and throat and lung dis- eases, viz. : Formula of Bracelin's Chlorin Bac- tericide. — Solution No. 1 : Solution zinc chlorid parts 20 Solution arsenic chlorid. .. .parts 30 Hydrochloric acid part 1 Water parts 49 Solution No. 2: Solution chlorinated soda, standardized to 2.6% available chlorin parts 70 Corrective parts 30 Note. — The corrective consists of menthol, camphor, eucalyptol and methyl salicylate dissolved in alcohol and water. —P. M. Bracelin, M. D. Bradycrotine. Examination showed it to contain bromids and caffeine but not antipyrin or cocaine; it also contains syrups, etc. The bromids consist chiefly of potassium and sodium with some ammonium. — N. I. Brandsanal. This is a remedy for burns consisting, according to the manufacturers of car- bolic acid 1 part, picric acid 7 parts, glycerin 23 parts, and distilled water 1,000 parts. Brandreth's Pills. According to Hager, these consist of gamboge, podophyllin, evaporated poke- 690 THE STANDARD FORMULARY berry juice, saffron, clove and pepper- mint oil. According to Dr. D. S. Clark, in A. D., the following is the formula : Socotrine aloes gr. 120 Gamboge gr. 60 Castile soap gr. 30 Extract of colocynth gr. 20 Oil of peppermint drops 2 Oil of cinnamon drop ^ 1 Acacia and alcohol of each, sufficient Make 80 pills. Brandt's Swiss Pills. The following formula has been given by Brandt : Extract of aloes gr. 30 Extract of wormwood gr. 30 Extract of buckbean gr. 30 Extract of achillea moschata (very closely allied to yar- row) gr. 30 Extract of speedwell root or mountain parsley (bergpeter- silienkraut) gr. 45 Gentian powder sufficient Make 100 pills. Feldhaus has examined the pills, and found 37% aloes (not extract) and 50% gentian powder made into pills with gentian, buckbean or wormwood extract. Brassicon. Oil of peppermint fl.dr. 1 Camphor dr. 3 . Ether fl.dr. 2 Alcohol" fl.dr. 6 Essential oil of mustard, .drops 12 — Suddeutsche Apoth. Ztg. Briant's Sirop Antiphlogistique. Hager states that 1,000 g. of this syrup are made from 60 g. of pectoral fruit, 8 g. of pectoral tea (see N. F.), 4 g. of red poppy, 90 g. of gum arabic, 60 g. of mucilage of althea, 30 g. of mu- cilage of linseed, 600 g. of sugar, and a sufficiency of water. The "pectoral fruit" is composed of equal parts of figs, dates (deprived of stones), raisins and jujubes. Brinkerhoff's Ulcer Specific. According to Medical Waif, the fol- lowing is said to be the formula : Carbolic acid, crystal gr. 2 Solution iron subsulfate dr. 1 Glycerin dr. 2 Distilled ext. witchhazel dr. 5 To iVz ounces of water add 30 minims of this "specific" and half a teaspoon- ful of starch and inject into the rec- tum every night. It is used for rectal ulcers. For ulcers in ano, 10 to 15 drops of the "specific" are injected into the canal. British Oil. (Betton's British Oil.) I. Oil of juniper fl.dr. 1 Oil of turpentine fl.oz. 1 Oil of amber fl.oz. 4 Linseed oil fl.oz. 12 Barbadoes petroleum fl.dr. 4 American petroleum fl.dr. 4 — Parrish. II. Oil of turpentine fl.oz. 5 Barbadoes tar av.oz. 2 Oil of rosemary fl.dr. 2 — Cooley. Bromalin. (Bromethylformin.) It is in colorless laminae or white crystalline powder, which is freely sol- uble in water. Do not confound this with bromelin. It is used as an antiepileptic as a sub- stitute for the bromids. Dose : 30 to 120 grains per day, in wafers, or in mixture with syrup of orangre-peel. Bromamid. (Tribromanilin Hydro- bromid.) This is in colorless, tasteless odorless crystals, insoluble in water, sparingly soluble in alcohol. It is used as an antineuralgic in doses of 10 to 15 grains. Bromanodyne. This is a hypnotic preparation, each fluidram of which is stated to contain 15 grains each of potassium bromid and chlorid hydrate, and Vs grain each of extracts of henbane and cannabis indica. Brom-Eigon. This belongs to the class of com- pounds known as "eigons." They are made from albumin. This compound contains 11% of bromin. It is a white powder, nearly free from odor and taste. PROPRIETARY AND SYNTHETIC REMEDIES. (591 insoluble in water. It has no free bromin and only traces of hydrobromic acid. It is marketed in the powder form, also as a wine, each tablespoonful of which contains I grain of bromin in combination. Bromelin. This is the digestive principle of fresh pineapple juice. It is said to act like pepsin, and papain digesting pro- teids. Heat destroys it. It may be iso- lated by adding an excess of common salt to pineapple juice. Do not con- found this with bormalin. Brometone. (Acetone-Bromoform.) (159) This is in fine, white, prismatic cry- stals, of camphoraceous odor and taste. It is slightly soluble in water, soluble in alcohol and ether. It contains JJ% of bromin. It is claimed to have the anodyne and sedative action of the bromids without the disadvantage of producing bromism. The dose is 5 grains, dry or in capsules, 2 or 3 times a day. Bromidine. (215) A hypnotic, each fluidram of which is stated to contain 7% grains each of chloral hydrate and potassium bromid, and Vs minim each of fluid extracts of henbane and cannabis indica. Bromine-Iodine Compound. This is described as a perfect, per- manent, aseptic solution of iodin, bromin, phosphorus, thymol and men- thol, chemically united. Brominol. (128) This is a combination of iodin and oil of sesame, similar to bromipin. It is recommended for epilepsy. Bromipin. (130) This is a bromin addition product of sesame (benne), oil containing 10% of bromin in organic combination. It is prepared by action of bromin chlorid on sesame oil, in sufficient quantities, theoretically calculated to produce the required brominization. It is a yellow, oily liquid, of a purely 44 oleaginous taste, and having a sp. gr. of about 0.995. It acts like the bromids, but as it yields bromin more slowly it is thought to have less tendency to produce brom- ism. The combination is not broken up in the stomach but a portion of the bromin is split off when it enters the in- testine. The oil with the remaining bromin is easily absorbed, and similarly to other fats it is largely deposited in the tissues where it is slowly split up. It is given in doses of 1 teaspoonful, increased in cases of epilepsy to 2 to 8 teaspoonfuls. It may be given pure, flavored with oil of peppermint or in emulsion with syrup and peppermint. It is also sold as a (diluted) zzVz% brominized oil, in capsules each con- taining 2 grams, and in tablets each con- taining 20 grains of the 33Vs% of oil. The following emulsion is recom- mended by Dr. Spratling : Bromipin fl.oz 2 Simple syrup fl.oz. 2 Spirit of peppermint fl.dr. 2 Mucilage of acacia fl.oz. 4 Brom-Lecithin. This is a preparation of bromin and lecithin containing 30% of bromin. It is made by dissolving lecithin in chloro- form, saturating with bromin, and then evaporating the solution to dryness in vacuo. It forms colorless, wax-like masses. It is used as a sedative in ner- vous disorders. The dose is 1 to 3 grains 3 times a day. Bromo-Caffeine. (105) This is stated to combine the active principle of guarana with excess of combined hydrobromic acid; the prepa- ration more than equals 1 grain of hy- drobromid of caffeine in each heaping teaspoonful. . Bromochinal/ (Bromoquinol — Qui- nine Dibromsalicylate.) This is in yellowish, bitter crystals, sparingly soluble in water, alcohol or ether. It is similar in action to qui- nine sulfate, but has hypnotic as well as febrifuge properties. 692 THE STANDARD FORMULARY Bromocoll. This is a combination of bromin, tan- nin and gelatin containing 20% of bromin. It is a yellowish, odorless, tasteless powder, insoluble in water and alcohol, soluble in alkaline liquids. It is used as a substitute for the bromids in epilepsy and other nervous disorders. It is also used externally as an antipruri- tic in various skin affections, either as a 20% ointment or a 10% solution. Bromodine. (76) Each fluidram is stated to contain Chloral hydrate gr. 15 Potassium bromid gr. 15 Ext. cannabis indica gr. Vs Ext. henbane gr. % Bromoform. This is a volatile liquid which decom- poses readily on exposure to light and air and must consequently be kept in dark or amber bottles, and be well stop- pered; is almost insoluble in water, and has a pleasant taste. It is very heavy, having the sp. gr. 2.83. It is used only in whooping cough. The dose depends on the severity of the case. For children of 1 year of age and under, 2 to 3 drops 3 times a day; children from 2 to 4 years of age, 3 to 4 drops 3 to 4 times daily; choldren up to 8 years of age, 4 to 6 drops 3 or 4 times a day. The doses should be cau- tiously increased by 1 drop the third day, in severe cases the second day. Scoville recommends the following mixture of bromoform which contains but little (or no) alcohol, is very palat- able, admits of accurate dosage, and is susceptible to change in dosage without altering the proportion of the other in- gredients : Bromoform fl.dr. 1 Tincture of tolu fl.dr. 2 Mucilage of acacia fl.dr. 4 Simple syrup fl.oz. 1 Spearmint water, to make. . .fl.oz. 4 Place the mucilage in the bottle, add an equal volume of syrup, then the bromoform and tincture in portions, shaking well after each addition. A thin emulsion results, to which the rest of the water and syrup are to be added with agitation. This emulsion slowly deposits but without separation of bromoform or tolu, and can be quickly made homogen- eous again by slight agitation. This mixture contains 2 minims of bromoform in 1 fluidram, and the amount may be increased or diminished if desired. Alcohol may be omitted al- together from the mixture by using syrup of tolu instead of the simple syrup and tincture of tolu. The following agreeable mixture was devised and suggested by Bedford: Bromoform m. 30 Alcohol fl.dr. 4* Glycerin fl.oz. 3 Tinct. cardamon comp fl.dr. 4 Mix in the order given. Bromoform Bronchial Anodyne. (143) Each fluidounce is stated to contain : Bromoform drops 8 Ammonium bromid gr. 24 Bengoin gr. 1 Ipecac gr. V2 It contains mostly glycerin instead of syrup as a vehicle. Bromo-Hemol. (Hemol Bromid.) This is hemol containing 2.7% bromin. It is a brown, insoluble powder. It is a nerve tonic and sedative in doses of 15 grains 3 times a day. Bromol. (Tribromphenol — Bromphe- nol.) This is a white crystalline powder or soft white crystals. It is easily soluble in alcohol, ether, chloroform and oils, less soluble in glycerin and diluted alco- hol, almost insoluble in water. It is a surgical and intestinal disinfectant in wounds, typhoid fever, summer diar- rheas, etc. It is used in 2 to 3% oint- ment or oily solution, or as dusting pow- der mixed with talcum. Dose : Single, 1 to 3 grains ; daily, 8 grains. Bromolein. This is an addition product of the unsaturated fatty acids of almond oil; PROPRIETARY AND SYNTHETIC REMEDIES. 693 it contains 20% of bromin. It is an odorless, tasteless, yellow liquid which is used instead of the ordinary bromids. Bromo-Mangan. (Liquor Ferri-Man- gani Bromopeptonati "Diete- rich.") This is Ferro-Mangan "Dieterich" (which see) with the addition of 3% of bromopeptone. The latter contains 11% of bromin. It is a clear, dark brown li- quid of agreeable odor and taste. It is a reconstructive tonic, blood-making adju- vant and a sedative, and is claimed to be useful wherever anemia is associated with nerve impairment, as in epilepsy, neurasthenia, hysteria, etc. Bromophtharin. Said to be a mixture of zinc oxid, calcium oxid, calcium carbonate, sodium sulfate, and sand. — Rundsch. Bromoquinol. See Bromochinal. Bromotan. (Methylene Bromtannin Urea.) This is a brownish-white, odorless, tasteless powder. It is used as a 10% dusting powder or a 10% ointment in skin eruptions, itching, rash, efc. Brom-Protylin. (98) This is a yellowish powder, of a char- acteristic bromin odor and taste. It con- tains 2.y% of phosphorus and 4% of bromin combined with albumin. It is used as a nerve nutrient in epilepsy, hysteria and other neuroses. The dose is 10 to 20 grains 3 times daily. It is put up in powder form and 4-grain tab- lets. Bromural. (109) This is in small, white, almost taste- less needles which are easily soluble in hot water, ether, alcohol or alkalies, but less readily in cold water. It is a nerve sedative and hypnotic for inducing sleep in functional nervous disorders. It is valueless in insomnia where pain, ex- citement or delirium exist. The dose as a nerve sedative is 5 grains, as a soporific 10 grains. It is supplied in the form of powder and 5-grain tablets. Bronchiline. (162) Each teaspoonful is stated to repre- sent Mullein gr. V2 Horehound gr. V2 Senega gr. V2 Ipecac gr. V2 Bloodroot gr. Y2 White pine gr. V2 Wild cherry gr. 2 Pine tar gr. 1 Chloroform gr. V2 It contains about 1% of alcohol. Bronchoids. (211) A mixture put up in capsules each 1 of which is stated to contain: Heroin gr. 1/16 Creosote * m. 1 Eucalyptol m. 1 Te.rebene m. 2 Bronchol. (141) This is put up in the form of soft elastic capsules each containing: Oil of sandalwood m. i 1 /^ Terebene m. 1 Creosote m. 1 Eucalyptol m y 5 Strychnine gr. 1/100 Olive oil m. 5 Brotanilid. (137) The claim of the manufacturer is that this is a mixture of acetanilid, sodium bromid, caffeine citrate and so- dium bicarbonate. Brou's Injection. See Injection Brou. Brown's Hair Dye. Pyrogallic acid gr. 225 Sodium sulfite gr. 38 Alcohol fl.oz. 1 Water fl.oz. 3 — N. I. Brown's Male Tern Vermifuge. The following makes a similar prep- aration (N. I.) : Fluid extract of male fern, .fl.oz. 3 Simple syrup fl.oz. 5 Oil of wintergreen drop 1 Buckingham's Whisker Dye. According to Dr. Schacht, this con- sists of % gm. of silver nitrate and 2Y2 gm. ammonia mixed with 40 cc. distilled water. cm THE STANDARD FORMULARY Bullrich's Salt. Sodium bicarbonate is now dispensed for this. Bugeand's Tonic-Nutritive Wine. Cocoa beans, freshly roasted and coarsely powdered gr. ioo Calisaya bark, contused g. 120 Cassia bark g. 10 Simple syrup g. 200 Sherry wine g. 200 Brandy g- 400 Macerate the cocoa with the brandy for 2 days, add the other ingredients, macerate for 8 days, agitating fre- quently, then filter.— H. Bull's Blood Syrup. Potassium iodid av.oz. 1V2 Red iodid of mercury ..gr. 2 Tincture of poke root fl.dr. 3 Comp. syrup of stillingia. . .fl.oz. 6 Simple syrup, to make fl.oz. 16 —Nat. Dr. Bumsted's Gleet Cure. The following is said to be the form- ula : Zinc sulfate gr. 10 Extract of opium gr. 60 Glycerite hydratis, U. S. P.. fl.dr. 1 Glycerin fl.dr. 4 Water fl.cz. 4 — W. D. Burdock Seed Compound. (36) This is stated to contain in each fluid- dram, burdock seed, bamboo brier root, stillingia root, red clover tops, each 10 grains, poke root, 6 grains, coriander seed, 3 grains, prickly ash berries and potassium iodid, each 1 grain. Burin's Pills of Iron and Manganese Carbonate. Ferrous sulfate, crystal gr. 150 Manganese sulfate, crystal. . .gr. 53 Potassium carbonate, pure...gr. 150 Sugar gr. 40 Althea, powder, sufficient. Triturate the two sulfates with the carbonate until reduced to a moist mix- ture, incorporate the sugar and althea, make a mass, and divide into 150 pills. Each pill contains about % grain of iron carbonate and % grain of man- ganese carbonate. — H. Burin-Dubuisson's Lozenges of Lac- tate of Soda and Magnesia with Pepsin. Magnesium lactate gr. 50 Sodium lactate gr. 50 Pepsin, pure gr. 45 Sugar av.oz. 3 Tragacanth gr. 60 Water sufficient Make into 100 troches. — H. Burnett's Cocoaine. The manufacturers state that this preparation holds, in a liquid form, a large proportion of deodorized cocoanut oil. Tt contains 50% of alcohol. Butipyrine. This is another name for trigemine, a compound of butychloral hydrate with pyramidon. See Trigemine. Butler's Elixir of Brandy. Nutmeg gr. 40 Cardamom gr. 60 Rhubarb gr. 60 Lavender flower gr. 60 Cinnamon gr. 60 Ginger gr. 60 Extract of licorice, powder.. gr. 360 Brandy fl.oz. 16 Water fl.oz. 8 Mix the drugs, reduce them to coarse powder, macerate in the mixed brandy and water for 14 days, agitating thor- oughly each day, and filter. It may also be prepared by percolation. — Lloyd's Elixirs. Butyromel. Fresh butter av.oz. 2 Honey av.oz. 1 Mix until a homogeneous mass is obtained. — Coblentz. Bynin. (2) This is a thin extract of malt. Bynin Amara. This is described as an analogue of Easton's Syrup (syrup of the phosphates of iron, quinine and strychnine), but much pleasanter to take and easier of assimilation. Bynin Emulsion. This is described as an emulsion of cod-liver oil with calcium and sodium hypophosphites in "bynin." PROPRIETARY AND SYNTHETIC REMEDIES. 695 Byno-Hemoglobin. This is described as containing i dram of hemoglobin in I ounce of "bynin." Byno-Hypophosphites. (2) This is described as an analogue of compound syrup of hypophosphites, "bynin" (liquid malt) replacing the syrup. Bynol. This is described as "the perfected malt and oil, free from taste and odor of cod-liver oil." Butyl-Chloral Hydrate. (Croton- Chloral Hydrate.) This is in pearly white laminae, having a pungent but not acrid odor and an acrid, nauseous taste. It is soluble in about 50 parts of water and in its own weight of glycerin or alcohol. Its action is similar to that of chloral hydrate but it is less depressant and more analgesic. It has been especially recommended for facial neuralgia. Byrolin. This is a mixture of boric acid, gly- cerin and lanolin, intended for cosmetic purposes. Cachet Hemo-Calx. (81) Each cachet is stated to contain Nuclo glycophos. calx gr. 5 Hemogallol gr. 2% Arsenous acid gr. 1/60 Strych. phosph gr. 1/60 Quin. phosph gr. 1 "Nuclo glycophosph. calx" is de- scribed as a combination of nuclein and "glycophosphate" of lime. Cacodyle Bengue Pills. Each pill is stated to contain 2 centi- grams of cacodylate of sodium. Cacodylic Acid. (Dimethylarsenic Acid.) This contains 54% of arsenic. It is in white, odorless crystals, soluble in water and in alcohol. It has been used in psoriasis, diabetes, leucocythemia, etc., in doses of V2 to 1 grain 3 or 4 times a day. The dose by injection is % grain every day or every other day, It is now mostly superseded by its sodium salt. Cafetonique. (105) This is a granular effervescent prepa- ration, each heaping teaspoonful of which is stated to contain 1 grain of caffeine, 5 grains of saccharated pepsin, 2 grains of bismuth citrate and 1/100 grain of strychnine. Caffeine Sodio-Benzoate. This is a preparation of the N. F. containing 50% each of caffeine and sodium benzoate. It is soluble in 2 parts of water. Caffeine Sodio-Cinnamate. See Hetol-Caffeine. Caffeine Sodio-Salicylate. This is a preparation of the N. F. containing 50% each of caffeine and sodium and sodium salicylate. It is sol- uble in 2 parts of water. Caffeine Sulfocarbolate (or Sulfophe- nate). It is in white, odorless, astringent, bitter, scaly crystals or powder, and is soluble in water. It is used as an antiseptic and as- tringent in cholera morbus, infectious diarrhea, intestinal ulcer, etc. Dose: 5 to 15 grains in solution. Caffeo-Bromide Compound. (17) This is a granular effervescent prep- aration, stated to contain hydrobromic acid, caffeine and acetanilid, used for headaches, nervousness, etc. Caffeotanilid. (17) This is said to be composed of ace- tanilid, sodium bicarbonate and caf- feine. Caffeotanilid Compound. This is stated to be composed of "caffeotanilid," 19 parts, capsicum 1 part, tincture of digitalis 12 parts, and mono- bromated camphor 2 parts. Calcauro. (Solution of Bromid of Gold, Arsenic and Calcium.) Ten drops of this are stated to con- tain 1/32 grain each of gold and arsenic bromids and 2 grains of calcium bro- mid. 696 THE STANDARD FORMULARY Calcalith. (Calcium Carbonate Com- pound with Colchicine.) (1) This is the formula given : Repurified calcium carbonate, 10 grains; lithium carbonate, I grain; colchicine, 1/500 grain; in aromatic combination. This is used as a remedy in various forms of uric acid diathesis. Calcidin. (1) This is described as "calx iodata" or "iodized calcium" and is stated to con- tain 15% of iodin. Calcium Eosolate. Chemically this is calcium trisulfoace- tylcreosote. It is a gray powder of slightly pungent odor and acrid taste. It is soluble in about 10 parts of water, very slightly soluble in alcohol, and is readily dissolved with the aid of hydro- cloric or citric acid. It contains about 25% of creosote. It is used in diabetes and some cases of phthisis. The dose is 5 to 20 grains 3 times a day. Calcium Glycerophosphate. This is a white crystalline powder, sol- ble in 40 parts cold water but almost insoluble in boiling water or alcohol. According to the investigations of Dr. de Pasqualis, lecithin, the chief phos- phorus constituent of blood, is decom- posed during digestion into chlorin and glycero-phosphoric acid; the latter thus represents the form in which phosphorus is assimilated and is indicated when it is desired to augment the amount of phosphorus in the system. The glycero-phosphates are therefore rational substitutes for phosphorus and may be given whenever the latter is in- dicated. They give striking results in exhaustion of the nervous system, whether due to metabolic loss or to in- sufficient assimilation. In various forms of phosphaturia and in many cases of neurasthenia, and in muscular atrophy, the treatment has been found beneficial, also in the pains of locomotor ataxia, in sciatica, lumbago, Addison's disease, rickets, osteomalacia, etc. The dose is 2 to 5 grains 3 times daily. Calcium Ichthyol. This is a calcium salt of sulfichthyolic acid, and is therefore the calcium analogue of ordinary ichthyol. It is a brown, tasteless powder. Calder's Saponaceous Dentifrice. The following makes a similar ar- ticle : Powdered castile soap av.oz 4 Precipitated chalk av.oz. 2 Magnesium carbonate av.oz. 1 Sugar av.oz. 1 Oil of wintergreen to flavor — N. I. Calisaya Cordial. (194) Each fluidram is stated to contain Calisaya, true gr. 5 Pepsin sac gr. 3 Erythrox. coca gr. 1 Iron pyrophos gr. 1 Viburnum opulus gr. 1 Gentian gr. 2 Strychnia sulph gr. 1/100 With vegetable aromatics. Calolactose. (181) The following is its composition ac- cording to the manufacturers: Calomel part 1 Bismuth subnitrate part 1 Milk sugar parts 8 This mixture is triturated by steam power for 12 hours. Calomelol. (Soluble or Colloidal Cal- omel.) According to the patent process, this is made by acting on a solution of so- dium chlorid in the presence of a pro- teid with mercurous nitrate and precipi- tating the water-soluble colloidal salo- mel by means of alcohol. The precipi- tate is washed with alcohol, redissolved in water with the aid of a small amount of alkali, and from this solution the colloidal calomel is obtained either by evaporation of by precipitation with alcohol. It is a grayish-white, odorless and tasteless powder; it is soluble in water, forming an opalescent solution, and is insoluble in alcohol. It is precipitated from its aqueous solutions by acids, the precipitate being redissolved by alka- lies. It should be protected from light PROPRIETARY AND SYNTHETIC REMEDIES. 697 It contains 80% of calomel and 20% al- buminoids. Its action on the system is the same as that of calomel, but it is claimed ta be superior because of its solubility in water, acting more rapidly and effi- ciently. The dose is the same as that of calomel. Externally it is used as a dusting powder, mixed with an equal quantity of starch, or starch and zinc oxid, or in the form of ointment. Calomelol Ointment. This is made by mixing 45 parts of calomel with 55 parts of lard. It is a substitute for mercurial ointment over which it has the advantage of cleanli- ness. The dose is 90 grains daily for inunction in syphilis. Calox. (121) This is a dentifrice powder contain- ing calcium dioxid. Patents were grant- ed May 1904, and Oct. 1905, for denti- frices, the specifications for the first be- ing as follows : A suitable dentifrice may consist for example of 95% of pre- cipitated chalk, 3% of powdered castile soap, 2% of calcium dioxid, and flavor- ing and coloring matter as desired. The wording of the second patent specifications is : A suitable dentifrice may consist of 96% of precipitated chalk, 3% of powdered castile soap, 1% of a percarbonate or perbonate of /an alkali or alkaline salt, and flavoring and coloring matter as desired. Camphacol. (116) This is the camphoric acid ester of methylene diguaiacol and a related body to guaialin. It is a crystalline substance given in doses of 5 to 20 grains as an antispasmodic, sedative and internal antiseptic. Campho-Ichthyol Ointment. (215) This is stated to be composed of phenol camphor, ichthyol, zinc ozid, lan- olin, and benzoinated lard. Camphoid. Collodion part 1 Camphor part 1 Absolute alcohol part 1 Campho-Phenique. This is an efficacious antiseptic which is stated to contain 50% of carbolic acid in its constitution. It is also claimed to be a chemical combination contain- ing in 1,000 parts, 495 parts of camphor and 505 parts of carbolic acid. Campho-Phenique Powder. The manufacturers state that "this substance is pure liquid campho-phe- nique held in a state of absorption by an inert, unirritating powder." Camphor Phenate. (198) This is described as a combination of phenol and champhor, as not miscible with water or glycerin, but may be di- luted with a vegetable, animal or min- eral oil or fat. Camphorated Phenol-Petrogen. (221) This is stated to contain 1 part of crystal carbolic acid, 3 parts of camphor, and 5 parts of liquid petrogen. It is used as an antiseptic application to wounds, boils, etc. See also Petrogen. Camphoric Acid. This is an oxidation product of cam- phor. It is in colorless crystals, melt- ing at about 180 C. It is freely sol- uble in alcohol and ether, sparingly in chloroform, oils or water. It is used as an antiseptic, and disinfectant for ty- phoid stools. In 1 or 2% solution it is used as a gargle or spray in angina and bronchitis, in 3 to 6% solution for lary- gngeal tuberculosis. Internally it has been administered in doses of 15 to 30 grains, 3 times daily, to prevent the night- sweats of phthisis. Camphoroxol. This is described as a combination of hydrogen peroxid with some alcohol and 1% of camphor. It is used as an anti- septic application for ozena and otitis media. Camphossil. This is a condensation product of cam- phor and salicylic acid which forms a crystalline, fat-like paste, of soapy feel- ing and camphoraceous odor, insoluble H98 THE STANDARD FORMULARY in water. It has the odor of camphor but is almost tasteless. It is given in- ternally in the treatment of typhus fever and disorders of the intestinal tract. The dose is 8 grains. Cancroin. This is a serum introduced by Adam- kiewicz as a remedy for cancer. It is furnished in different strengths. Cande's Lait Antephelique. According to Wittstein's analysis, this is composed of : Corrosive sublimate g. 10 Ammonium chlorid g I Lead sulfate g. 7 Camphor g. 2 Egg white g. 140 Water g. 840 — H. Cannabin Tablets. (92) The following formula is given: Cannabin gr. 1/10 Zinc phosphid gr. 1/10 Strych. phos gr. 1/40 Avenine gr. 1/200 Cannabine Tennate. A yellow or brownish powder of a slightly bitter but strongly astringent taste. It is sparingly soluble in water, alcohol or ether ; quite readily soluble in acidulated water. It is used as a hypnotic and sedative in hysteria, nervousness, etc. Dose : 4 to 8 grains at bedtime in a powder with sugar. Maximum dose : Single, 15 grains; daily, 30 grains. Cannabine itself is a liquid alkaloid derived from cannabis indica. Cannabis Indica Cigarettes. (204) These are stated to contain cannabis indica and harmless medicinal herbs. They are used for bronchitis, asthma, hay fever, etc. Capillin. This is described as a condensation product of tannin, chloral and resorcin, which has properties resembling captol, being used as a hair restorer and in the treatment of dandruff. Capillin hair re- storer is made from capillin 2, chloral 2, salicylic acid 1, soap liniment 4, 70% alcohol to make 200, oil of rose geran- ium and oil of lavender flowers, each 10 drops. Caprenalin. (221) This is described as the active pressor principle of the suprarenal capsules, made according to the process of Pro- fessor John J. Abel. Capsic-Digest Tablets. (17) These are put up in three styles. Formula A is composed of capsicum 1/10 grain, nux vomica V± grain, pepsin (1:3000), grain, pancreatin, diastase, lactic and muriatic acids and willow charcoal to make a 5-grain tablet. Formula B has only H grain pepsin but enough of the last five ingredients are added to make a 5-grain tablet. The laxative style contains 1/10 grain of capsicum, Y\ grain of extract of nux vomica, 1 grain of pepsin (1:3000), I grain of extract of cascara, and pancrea- tin, diastase, lactic and muriatic acids, and willow charcoal to make a 5-grain tablet. Capsicol. (148) This preparation is stated to represent olive oil, capsicum, camphor, turpentine, oil of origanum, oil of juniper and euca- lyptol. It is used as counter-irritant application in rheumatism, sciatica, neu- ralgic gout, etc. It is put up in collap- sible tubes. Capsolin. (159) This is stated to contain oleoresin of capsicum, camphor, and oils of croton, cajeput and turpentine. It is put up in collapsible tubes. It is recommended as a convenient, efficient and non-irritating substitute for mustard plasters, turpen- tine stupes and other domestic counter- irritants. Captol. This is described as a condensation product of tannin and chloral, having none of the objectionable properties of tannin nor the irritating ones of chloral, whik it possesses a peculiar effect or diseased hairy scalps Tt is in the^ form PROPRIETARY AND SYNTHETIC REMEDIES. 699 of a dark-brown, hygroscopic powder, not easily soluble in cold water, more so in warm water and alcohol ; it is decom- posed by alkalies but not by acids. It is used as an application in the form of a i to 2% alcoholic solution to the scalp for dandruff and loss of hair due to dandruff. It is stated to produce rapid and effective results. It is also recom- mended as a prophylactic to prevent loss of hair. The compound spirit of captol put up is said to consist of 2 parts each of cap- tol, chloral hydrate and tartaric acid, 1 part of castor oil and 200 parts of 65% alcohol. Carbenzol. (1) This is described as "a bland, thin oil containing sulfur in natural combination. It is obtained by distillation from a bi- tuminous shale carrying large quantities of animal matter. In odor and color it somewhat resembles ichthyol, but unlike this and similar products it is a natural oil, not a chemical production from the crude material. It does not stain the skin. Its odor (which is far from dis- agreeable) may be completely disguised by the addition of oil of eucalyptus or cassia. It may be applied full strength or it may be diluted with some bland fixed oil or liquid paraffin, or made into an ointment with wool fat, petrolatum or lard. It is recommended as an anti- septic, germicide and antipruritic in ec- zema, erysipelas, pimples, boils, herpes, carbuncle, etc. There is also a Carbenzol Soap which is described as a non-alkaline, superfat- ted soap containing 10% of carbenzol. Carbolate of Iodin Inhalant. What is usually sold and used under this name is practically identical with the carbolized solution of iodin of the N. F., which is prepared as follows : Compound tincture of iodin. fl. dr. H Carbolic acid, crystal, lique- fied by gentle heat gr. 11 Glycerin , fl.dr. 5 Distilled water, to make, , , ,fl,Qg, 4 The compound tincture of iodin is composed of 15 grains of iodin, 30 grains of potassium iodid and 1 fluidounce of alcohol. Carbolineum Avenarius. This is a proprietary preparation rec- ommended for use in preserving woods from decay, dry rot, etc., by application as a paint. Dr. Baker, chemist in the laboratory attached to the appraiser's department at New York, analyzed it some years ago and found 1 it to be a wood tar oil, of the sp. gr. 1.1235, and "the product of the destructive distilla- tion of wood, certain of its characteris- tic constituents (particularly the ter- pene hydrocarbons) being wood tar de- rivatives not found in coal tar." Carbo-Peptine Wafers. (88) These are stated to contain pepsin, pancreatin and ptyalin. Carbolic Smoke Ball. This is composed chiefly of licorice root, flour, white hellebore and some tarry body having the odor of carbolic acid. — N. I. Caripeptic Liquid. (199) This is stated to represent all the con- centrated, active enzymes of Carica pa- paya (papaw). It contains about 15% of alcohol. Caripeptic Powder. This is stated to represent the purified active enzymes of Carica papaya in an impalpable powder. Caripeptic Tablets. These are stated to contain the active digestive ferments of Carica papaya (papaw) with calcium glycerophosphate, ginger and aromatics. Caripeptic Tablets with Charcoal and Soda contain the active digestive fer- ments of Carica papaya with willow charcoal, sodium bicarbonate and aro- matics. Carl-Aperient. (63) This is stated to be an effervescent laxative, consisting of artificial Carlsbad salt reinforced with sodium phosphate and magnesium sulfate. TOO THE STANDARD FORMULARY Camogen. (6) This is described as a glycerite of bone-marrow, containing 60% of red marrow and 25% of unaltered fibrin of ox blood, with albumin, suspended in glycerin. It is used as a hematinic, chiefly in pernicious anemia. Dose: 1 to 2 tablespoonfuls 3 times daily, after meals. Carnolin. This is an aqueous solution containing iH% of formaldehyde. Carnos. A recently introduced dietetic, said (Pharm. Centralh.) to be prepared from well-boiled yeast and germinating barley malt. It is in the form of an extract rendered palatable by means of salt and condiments. Caroid. (100) This is stated to be a concentrated extract of Carica papaya (papaw). It is in the form of a powder and is used as a digestive agency and an aid to im- paired digestion. It is also put up as an essence in liquid form, also in tablets either plain or laxative (with cascara, podophyllin and ext. of belladonna), or with soda or charcoal or nux vomica or bana-diastase. Carriers Compound Syrup of Euca- lyptol. Each fluidounce is stated to represent Eucalyptol m. 4 Creosote m. 2 Iodoform gr. 1 Glycerin, syrup of tolu, each sufficient Carvacrol. (Oxycymol.) This is a phenol extracted from vari- ous origanum oils. It is a thick oily substance. It is an antiseptic, similar in properties to thymol. Cascanata. (Elixir Cascanata.) (170) This is described as combining the ac- tive principles of cascara sagrada, tri • folium, rum'ex, gentian and rhubarb and holding in solution phosphate of soda and magnesia. Cascara Carminative. (143) Each fluidounce is stated to represent Cascara sagrada gr. 240 Wahoo gr. 24 Blue flag gr. 16 Sodium phosphate gr. 40 Sodium salicylate gr. 16 Aromatics. Cascara Cathartic Pills, Hinckle's formula. (212) Each pill contains Cascarin gr 1/4 Aloin gr. 1/4 Podophyllin gr. 1/6 Extract of belladonna gr. 1/8 Gingerine gr. 1/8 Strychnine gr. 1/60 Cascara Compound (Sydenham) Each tablet is stated to contain Cascarin gr. 1/8 Aloin gr. 1/8 Podophyllum gr. 1/12 Extract of belladonna gr. 1/16 "Gingerine" gr. 1/16 Strychnine gr. 1/120 Cascara Comp. Pills, Robin's. See Robin's Pill Cascara Comp. Cascara Compound, Tonic Laxative. (108) Tablets each said to contain Extract of cascara sagrada.. gr. 2 Podophyllin gr. 1/8 Extract of belladonna gr. 1/16 Cascara Cordial. (159) It is stated on the bottle that each liter represents 250 grams of cascara and Z7 grams of berberis oquilfolium, and is flavored with carminatives and aromatics. Cascara Evacuant. (159) This is described as an active and agreeable preparation of the unchanged bitterless glucosides of cascara sagrada, possessing all the desirable laxative prop- erties of this valuable drug. It is a dark red-brown liquid of a bitter but not un- pleasant taste. The dose as a laxative is 10 to 15 min- ims 3 times a day; as a purgative, 20 to 30 minims, morning and evening. One fluidram may be given in obstinate cases. PROPRIETARY AND SYNTHETIC REMEDIES. 701 Cascara Laxative Tablets. (160) Each tablet is stated to contain Fl. ext. cascara m. 12 Comp. aloin powder gr. 1 2/5 Cascara-Peptonoids. (13) Each tablespoonful is stated to repre- sent: Alcohol (by volume) 16.5% Extr. cascara sagr. fl m. 30 Tr. nux vomica m. 1 Proteids (peptones and pro- peptones) 5-25% Lactose and dextrose n.3% Cane sugar 2.5% Mineral constituents (ash) 0.95% Cascara Potent, Fluid. (143) This is described as a concentrated preparation of cascara sagrada nearly free from bitterness. Each pint repre- sents 20 ounces of drug. Carminative aromatics are added to render the prep- aration more palatable and to counteract the griping tendency of the drug. Cascara Tonic Laxative Globules. (159) Each globule is said to contain 3 grains of the bitter glucosides of cascara sa- grada suspended in a bland fixed oil to which aromatics have been added. Cascarans. (20) This is in the form of tablets which are prepared from cascara sagrada. Cascarenna. (159) Each fluidounce is stated to represent Cascara sagrada gr. 120 Senna gr. 120 Rochelle salt gr. 24 Chenopodium gr. 8 Pumpkin seed gr. 8 Sodium bicarbonate ---gr. 4 Aromatics. Cascarets. (Candy Cathartic.) These are tablets said by the manufac- turers to contain cascara sagrada and senna combined with antiseptics and aro- matics, each tablet representing 10 min- ims of fluid extract of cascara sagrada. Cascarin. Ordinary cascarin is believed to be merely powdered extract of cascara sa- grada. Cascarin Comp. Tablets. (182a) Each pill is stated to contain Y A grain each of cascarin, aloin and podophyllin. The No. 2 contain Cascarin gr. 1/4 Aloin gr. 1/4 Podophyllin gr. 1/6 Ext. belladonna leaves gr. 1/8 Oleoresin of ginger gr. 1/8 Strychnine sulfate gr. 1/60 Cascarine-Leprince. Cascarine (usually spelled cascarin in this country) is the name given by Le- prince to a constituent of cascara sa- grada, isolated by him in 1892 and be- lieved by him to be the active principle of the drug. It occurs in odorless, taste- less needles, insoluble in water, soluble in alcohol. According to Laffond, it is cholagogue and laxative, but not a drastic purgative. The adult dose is 2 to 5 grains. It is put up for the market in the form of pills, one or two of which is a dose at bedtime. Cascaroids. (89) These are soft, elastic capsules, each containing 2 or 3 grains of extract of cascara sagrada. Cascaroma. (142) This is stated to be a palatable and ef- fective preparation of cascara sagrada, a full-strength U. S. P. fluid extract. It contains the entire soluble constituents of the bark, the bitter principle being disguised (not removed). Case-Aromatic. (198) This is described as a fluid extract of cascara sagrada deprived of its bitter principle and aromatized and sweetened. Cassia Compound. (34) This is stated to be "a palatable and efficient liquid laxative, cathartic and cholagogue, each fluidounce representing 50 grains of Alex, senna, 25 grains of jalap, resin of podophyllin % grain with aromatics." 02 THE STANDARD FORMULARY Castoroids. (89) These are soft, elastic capsules, each containing i gram of castor oil, K drop of croton oil and y 2 drop of oil of anise. Castrole. (22) This is described as a powdered castor oil. Catalgine. This is stated to contain 20% of acet- anilid with "benzo-salicylate" of am- monia, caffeine, potassium and sodium. Catalysin. (17) "The digestive ferments represented in this preparation are pork, rennet and poultry pepsin, pancreatin, ptyalin and diastase, associated with lactic and mu- riatic acids." Catani's Specific. This remedy for uric acid diathesis is a mixture of Lithium carbonate part 1 Sodium bicarbonate parts 2 Potassium citrate parts 4 Mix well, reducing to fine powder. —Ph. Post. Catholicons. The patent medicines known as "cath- olicons" are remedies designed for fe- male complaints. Caulophyllin Comp. Pills. See Girard Uterine Tonic. Cauvin's Pills. These are a French preparation con- taining, according to Hager, the follow- ing: Rhubarb gr. 10 Gamboge gr. 20 Aloes gr. 30 Jalap gr. 30 Divide into 30 pills. Cazeaux Nipple Ointment. White wax av.oz. 9 Sweet almond oil fl.oz. 2 Honey fl.oz. 1 Peru balsam fl dr. 5 — Kilner. Cealgic. This is stated to consist of acetanilid, caffeine citrate, ammonium chlorid, "neu- rodin," sodium bicarbonate, and digitalin. It is put up in powder and tablet forms, plain and in combinations with codeine, heroin, quinine, and salol. Celery, Caffein and the Bromides. (36) A granular effervescent preparation for relieving migraine and nervous head- aches. It is said to have practically the same composition as their Celery and Caffein, f. e., celery seed, 5 grains, "bromide of caffein and sodium," 1 grain. Celery Cordial. (198) Each fluidounce is stated to contain 48 grains each of kola, celery seed and vi- burnum, and 64 grains of coca leaves with aromatics. Celloidin. (178) This is the name given to a prepara- tion of the character of purified pyroxy- lin, U. S. P. It is prepared by dissolving pyroxylin in a mixture of alcohol and ether, filtering, and recovering the solv- ent from the filtrate. It is supplied in shreds immersed in water. It is free from acids. Dissolved in ether and alco- hol it forms a bright and clear collodion, no clearing or filtering being necessary. It is used for surgical, plotographic and microscopic purposes. Cellotropin. (Monobenzoyl-Arbutin.) This is a white odorless, tasteless powder, sparingly soluble in water, read- ily so in alcohol. It is used in tubercu- losis and scrofula. Cellulin. (100) This is described as a sugar, starch, fat and peptone-splitting ferment deriv- ed from fungi. It is marketed as a light brown powder and in tablet form. Cellulo. (Oxychlorine Dressing.) This is the formula given : Glycerin per cent 50 "Oxychlorine" per cent 4 Cellulose per cent 20 "Dehydrated silicate of alumi- num with magnesia". . .per cent 26 Cephalopin. This is an oily extract of the fresh nerve substance and compounds soluble in oil such as mvelin and lecithin, It is PROPRIETARY AND SYNTHETIC REMEDIES. '03 recommended for hypodermic use in strychnine poisoning and nervous dis- eases. Ceralin (Koempel). (182a.) This is an antiseptic ointment which is stated to contain boric acid and "ben- zothymol." Cerevisine. This is described as "pure desiccated yeast." Cerolin. (26) This is a fatty substance derived from yeast. It is used internally in place of yeast for furunculosis, acne, etc., but is more cathartic than yeast. It is put up in pills each containing i/io gram. Cetiacol. See Palmiacol. Chable's Sirop Adstringent. This is a solution of io g. of iron cit- rate in 300 g. of simple syrup. — H. Chalybeate Pills. (212) These are stated to contain 1^2 grains each of ferrous sulfate and potassium carbonate. Pill Chalybeate Comp, are stated to contain 2^2 grains of "chalybeate mass" and Y% grain of extract of nux vomica. Pill Chalybeate Comp. Improved con- tain V/z grains of "chalybeate mass" and 1/20 grain of extract of nux vomica. Chambard's Purgative Tea. According to Hager this is composed of senna leaves, strawberry leaves, hys- sop leaves, speedwell leaves, calendula flowers, and elder flowers. Chamomilla Comp. (76) This is stated to be a diffusible nerve tonic, made according to the formula of Dr. Thos. A. McBride, and containing the mother tinctures of cinchona, cham- omila, ignatia, phosphorus and nux vomica with aromatics. Chapoteaut's Morrhuol. See Morrhuol. Chapoteaut's Phospho-Glycerate of Lime. This is put up in the form of capsules, each containing 4 grains of this com- pound ; wine, containing 4 grains to the tablespoonf ul ; and syrup, containing 4 grains to the tablespoonful. Cheltenham Salt. This is the formula according to Ha- ger: Sodium sulfate, dried, Magnesium sulfate, dried, Potassium sulfate, Sodium chlorid, each, equal parts. Chemical Pood. The preparation known by this name is the Compound Syrup of Phosphate of the N. F. Chevalier's Life for the Hair. Lead sulfid g. 0.8 Iron sulfid g. 0.1 Lac sulfid gr. 1.5 Glycerin g. 100 Water g. 200 Flavor with rosemary and rose gera- nium oils. — Piper's analysis from H. Chichester Mixed Treatment Pills. (33) Each pill is stated to contain 1/20 grain of red mercuric iodid and 5 grains of potassium iodid. Chinaphenin. This is the quinine carbonic ester of phenetidin. It is a white, odorless and tasteless powder, sparingly soluble in water, readily soluble in alcohol. Acids dissolve it, but at the same time decom- pose it with the liberation of quinine, the mixture having of course the bitter taste of quinine. It combines the antiperiodic properties of quinine with the analgesic power of phenacetine with the advantage of being without taste and of not producing cin- chonism. It is used in la grippe, malaria, neuralgia, whooping cough, etc. It is given in doses of 5 to 20 grains ; in whooping cough, 2 to 5 grains, accord- ing to age. Chinoformin. This is described as a combination of quinic acid with hexamethylene tetra- mine, and is therefore the same as chi- notropin, which see. 704 THE STANDARD FORMULARY Chinol. (Chinoline or Quinoline Monohypochlorid.) This is a white, crystalline powder, al- most insoluble in water, soluble in alco- hol. It is used as an antiseptic in doses of 3 to 5 grains. Chinopyrin. See Quinopyrin. Chinosol. (Potassium Oxyquinolin Sulfate.) It is in bright yellow crystals, of faint, aromatic odor and unpleasant taste, is freely soluble in water, sparingly in alco- hol and ether. It is a powerful antisep- tic and germicide and may be used for disinfecting the hands for surgical or gynecological work. The discoverer of it claimed it to be superior to corrosive sublimate and carbolic acid. It has been used to destroy the bacilli of typhoid fever, diphtheria, cholera, etc. It has also been used internally in gastrointes- tinal diseases. Chinotropin. (Urotropin Quinate.) It is a white powder readily soluble in water. It is said to liberate formalde- hyde more freely than urotropin and thus its uric acid-solvent properties and its action upon the bacteria are more pronounced. It is used in gout and bac- illuria in doses of io to 20 grains 2 or 3 times a day. Chiodrastis. (211) Each^ fluidram is stated to contain Papain gr. 1 Pancreatin gr. 2 Hydrastis gr. 2 Chionanthus gr. 4 Cascara sagrada gr. 5 Antiseptic oils and aromatics, q. s. The preparation also contains 14% of alcohol. Chirata Compound. (40) This is stated to contain nux vomica, 3 parts, cephalanthus occidentalis, 5 parts, acid nitrohydrochloric dil, 5 parts, swertia chirata, 10 parts, taraxacum, 35 parts. Chloraethoform. This is a name given to a mixture of chloroform with 14% of ethyl chlorid. It, is stated to be safer and to act more promptly than unmixed chloroform. Chloralamid. (Chloralformamide.) This is now recognized by the U. S. P. under the name chloralformamide. It is in colorless, odorless, bitterish crystals, soluble in 20 parts of water and i x / 2 of alcohol, readily soluble in ether and glycerin. It is decomposed by hot solv- ents and alkaline liquids. It is used as a hypnotic in doses of 15 to 45 grains. Chloral- Ammonium (Tri-chloramido- ethylic Alcohol.) This is a white powder, soluble in al- cohol, slightly soluble in water. It is a hypnotic and analgesic in doses of 5 to 30 grains. Chloralbacid. This is described as a chlorin substitu- tion product of albumin containing 3% of chlorin. It is a yellowish-white pow- der, almost odorless and tasteless, and readily soluble in water. It is used in various gastrointestinal affections in doses of 10 to 30 grains before meals. Chloral-Caffeine. This is a white powder, readily soluble in water. It is used as an anodyne, anti- spasmodic, antirheumatic, and laxative in cases of obstinate constipation. The dose subcutaneously is 2 to 5 grains in divided doses, internally 3 to 8 grains at a dose. Chlora-Kaline. (181) This is a hypnotic, each fluidram of which is stated to contain 15 grains each of chloral hydrate and potassium bro- mid, and % grain each of extracts of henbane and cannabis indica. Chloralamid Elixir. See Elixir Chloralamid. Chloralia. (182) Each fluidram is stated to contain "15 grains each of pure chloral hydrate and purified brom. pot. and M$ grain each of gen. imp. ext. cannabis ind. and hyo- scyam." PROPRIETARY AND SYNTHETIC REMEDIES. 705 Chloralimid (not Chloral-amid). This is in colorless, inodorous insipid crystals which are readily soluble in al- cohol, ether, chloroform and oils, but is insoluble in water. Used as a hypnotic in doses of 15 grains. Chloralose. This is a compound of grape sugar and chloral It is in fine, colorless nee- dles, rather readily soluble in hot water and in alcohol, but is sparingly in cold water. It is used as a hypnotic. Dose : 3 to 12 grains. Chloralum. Prof. Fleck made an examination, on behalf of the Saxon Government, of chloralum solution, chloralum powder and chloralum wool and wadding. The liquid contained Aluminum chlorid 13-90% Calcium chlorid and sulfate. 3.11% Iron chlorid 0.42% Lead chlorid 0.15% Copper chlorid 0.10% Water, to mak 100.00% The powder, in addition to the above salt, contained 0.72% of chlorid of ar- senic and 32.15% of clay and sand. Fleck suggested that the solution was made as follows: "A calcareous clay, containing but lit- tle iron, is dissolved as far as possible, in fuming hydrochloric acid. The clear concentrated liquid above the undis- solved clay is drawn off in bottles and sold as chloralum." The name refers to its containing chlorid of aluminum. The residue with the liquid adhering, is evaporated in leaden pans, dried and sold as "chloralum powder." Cotton or wadding, soaked in the chloralum itself, wrung out and dried, furnishes the "chloralum wool and wadding." The arsenic, lead and copper found in it are impurities contained in the hydrochloric acid used as a solvent or they come from the vessels in which they are made. Chlorbutanol. (Acetone-Chloroform.) This chemical is sold commercially under the names chloretone and metho- form, which see. Chloretone. (Acetone-Chloroform.) (159) This is a white, crystalline, volatile compound having a camphoraceous odor and taste. It is soluble in 125 parts of water, in fixed and volatile oils and in glycerin, freely soluble in alcohol, ether, and chloroform. It is local anesthetic which is weaker in action than cocaine but is strong enough frequently to stop vomiting from gastric irritation. It is used as a local anesthetic in dentistry, it is a powerful antiseptic and is used as a preservative. It is given internally in doses of 5 to 20 grains ; hypodermic- ally it is used in the form of a satur- ated aqueous solution. See Chlorobut- anol. Chloretone Inhalant. This is a mixture of Chloretone parts 2 Camphor parts 5 Menthol parts 5 Oil of cinnamon part 1 Liquid petrolatum parts 187 It is used as an anodyne, antiseptic and emollient spray for the nose and throat. Chlor-Lactated Pepsin Powder. (160) This is the composition as given by the manufacturers : Saccharated pepsin, U. S. P. Pancreatin, N. F. ' Diastase or ptyalin. Lactic acid. Hydrochloric acid. For the elixir, see Elixir Chlor-Lac- tated Pepsin. Chlorobrom. This is an English specialty; it 's an aqueous solution containing potassium bromid and chloralamid. It is used as a hypnotic and is advocated for sea- sickness. Chlorol. This is said (Arch. Med. Beige) to have the following composition: Mercuric chlorid part 1 Sodium chlorid part 1 Hydrochloric acid part 1 Copper sulfate parts 3 Water parts 1000 706 THE STANDARD FORMULARY The sodium chlorid is added to ren- der the solution more stable ; the hydro- chloric acid to prevent the decomposi- tion of the corrosive sublimate in the presence of albuminoid matter; and the copper sulfate for its vomitive effects — in case the chloral should be taken in- ternally by mistake. Chlorolin. This is a liquid disinfectant. It con- tains 20% of mono- and trichloro- phenols. It is used as an antiseptic application to wounds in y 2 to 3% solu- tions. Chloro-Phenique. (163) This is described by the manufac- turers as "containing 5% of chloro- phenic acid combined with antiseptic es- sential oils, in aqueous solution, and is equal in antiseptic properties to a 20% solution of carbolic acid." It is said to be made by passing chlorin gas through phenol combined with the essen- tial oils. Chlorophenol. This is formed by the action of chlorin on carbonic acid. It is a volatile liquid which is used as an antiseptic inhalant in diseases of the respiratory organs in the following mixture : Chlor- ophenol, 14; alcohol, 4; oil of clove, 1; menthol, 1 part, may be added. From 15 to 30 drops are to be inhaled at a time. It is also applied to wounds, ul- cers, etc. Chlorsalol. See Parachlorsalol. Chloryl. See Anesthyl. Cholelysin. , This is said to be a compound contain- ing 20% of sodium oleate and 2.8% of albumen. It is used to stimulate the flow of bile and to counteract the ten- dency toward the formation of gall stones. Chologestin. (189) This is described as a combination of the "alkaline salt" of glycocholic acid and sodium salicylate from oil of win- tergreen, pure pancreatin, and pure so- dium bicarbonate. It also contains 15% of alcohol. It is a brown liquid which is described as a digestive cholagogue. Christadoro's Hair Dye. Xo. 1 contains 60 gr. of pyrogallic acid dissolved in 1 fluidram of alcohol and 4 fluidounces of distilled water. Xo. 2 consists of 1 av. oz. of silver nitrate dissolved in 1 fluidounce of dis- tilled water and 1 fluidounce of concen- trated ammonia to which is added y 2 av. oz. of gum arabic dissolved in 3 fluidounces of distilled water. — Era Form. Chroatol. This is terpine iodhydrate made by the action of iodin upon oil of turpen- tine. It is used in some skin diseases. Chromosot. This is said to be chiefly sodium sul- fite and sulfate. It is used as a disinfec- tant. Chrysarobin. This is a light yellow powder, very slightly soluble in water, slightly soluble in alcohol, ether and chloroform, freely soluble in alkalies. By oxidation it is converted into chrysophanic acid. It is employed in the treatment of va- rious skin diseases, in ointment of 10% strength. It is now recognized by the U. S. P. Chrysarobin, Oxidized. This is prepared by the action of so- dium peroxid on chrysarobin suspended in boiling water. It is a dark brown powder, insoluble in water, soluble in hot alcohol and chloroform. It is used in skin diseases in 5 to 10% ointments. It is said to be milder in action than chrysarobin. Churchill's Syrup. The syrup of hypophosphites U. S. P. is now dispensed for it. Originally it was made to contain 3 grains of calcium hypophosphite and 2 grains of sodium hypophosphite to the fluidram. PROPRIETARY AND SYNTHETIC REMEDIES. 707 Cinchonia Mixture. This has been said to consist cf Cinchonine alkaloid parts 12 Sugar of milk parts 60 Sodium bicarbonate part 1 Cincho-Quinine. This is a mixture of cinchonine, qui- nidine, and other alkaloidal salts remain- ing after the extraction of quinine from cinchona bark. Cineraria Maritima, Juice of. This remedy was introduced from Venezuela, where the plant is indigen- ous, by a Dr. Mercer. It is recommend- ed for arresting and improving partial blindness induced by cataract or other causes. Two drops of the juice are dropped into the pupil 3 times a day, continued for several months. Cinnamic Acid. (Cinnamylic Acid.) This is in white, odorless crystals, al- most insoluble in cold water, more solu- ble in hot water, soluble in alcohol and ether. It has recently been lauded as an antitubercular remedy. It is used intro- venously in quantities of ^ to ^ grain in the form of a 5% oil emulsion with 0.7% solution of sodium chlorid twice a week. It is also applied as a 5% emul- sion or alcoholic solution. In lupus it is applied in 5% alcoholic solution with 5% of cocaine. Citarin. (Sodium Anliydromethylene Citrate.) This is a white, granular, somewhat hygroscopic powder, having a faintly sa- line and acidulous taste. It is soluble in i l / 2 parts of water, insoluble in alcohol. Its solutions split off formaldehyde when heated, especially in the presence of alkalies. Acids also decompose it. This is one of the compounds which it is claimed increase the elimination of uric acid by forming very soluble com- pounds with that substance. It is rec- ommended for gout and chronic rheu- matism. The dose is 15 to 30 grains, largely diluted with water. 4b Citon Tablets. These occur in two forms, white and brown. The white consist of 1^2 grains of paraphthalein, 8 grains of sugar and 1/6 grain of menthol. The brown con- sists of 1^ grains of paraphthalein, 8 grains of sugar, i l / 2 grains of chocolate and 1/30 grain of vanillin. They are used as purgatives. Made in Colmar, Germany. Citrophen. (Paraphenetidine Citrate.) This is in white powder or crystal of faint but sour taste, soluble in 40 parts of water. It is an antipyretic and antineuralgic. It was introduced as a substitute for phenacetin. Dose : 8 to 15 grains. Citrosandalene. (41) These are capsules stated to contain sandalwood oil and potassium citrate. Citrozon. (42) This is stated to be a mixture of van- adinic acid, sodium chlorid, sodium cit- rate and 30% of seidlitz powder, the whole being an effervescent mixture. Each 100 g. contains .005 g. of vanadinic acid. Citrurea. This is an uric-acid solvent in tablet form, which is said to be a mixture of urea, citric acid and lithium bromid. Claflin's Mist. Phosphor. Co. See Mixture Phosphorus Comp. Clarke's Blood Mixture. Potassium iodid parts 40 Chloroform parts 8 Alcohol parts 150 Solution of potassa parts 5 Water parts 2250 Caramel parts 50 — N. I. Clavin. This is a substance obtained from er- got. It occurs as a powder which is sol- uble in water but insoluble in alcohol and ether. Its aqueous solution soon un- dergoes decomposition. It is marketed in two forms of tablets, each containing J/j 708 THE STANDARD FORMULARY grain of clavin, one form containing su- gar and intended for internal, the other containing salt and intended for hypo- dermic use. Claxton's Gout and Rheumatic Oil. Ammonia liniment, Alcohol, Spirit of soap, Spirit of camphor, Tincture of myrrh, Lard, equal parts of each. — Drog. Ztg. Cleary's Asthma Powder. Stramonium leaves parts 30 Belladonna leaves parts 30 Potassium nitrate parts 5 Opium parts 2 All should be in powder. — Ch. & Dr. Clerambourg's Grains de Vie. According to Hager, these are similar to the following: Cassia bark, powder gr. 30 Extract of cinchona gr. 75 Cape aloes, powder gr. 150 Syrup of orange m. 30 Make into pills each weighing 3 grains, or divide so that each pill will contain \ x /2 grains of aloes and 24 grain of ex- tract of cinchona. Clermont's Syrup of Arseniate of Iron. According to Hager, a very similar article may be prepared by dissolving 1 g. of ferrous arsenite in a small amount of acetic acid, diluting with some water, neutralizing with sodium bicarbonate, diluting with 'water to 200 g. and in this liquid dissolving 300 g. of sugar. Clifford's Shampoo Compound. The following is claimed to be its composition (N. I.) : Borax av.oz. 3 Potassium carbonate av.oz. 1 This is to be dissolved in 4 pints of water. Clin's Lecithine. See Lecithine Clin. Clinton's Cascara Active. (29) This is described as a palatable and highly active preparation of cascara sag- rada, each imperial fluidounce represent- ing one av. ounce of drug. Cloftlin Emulsion. (46) According to the statement of the manufacturers, the following is the com- position: Hypophosphite lime gr. 48 Hypophosphite manganese .gr. 24 Glycerin fl.dr. 6}4 Glycerite of senega (special) fl.dr. 1 Salts, solvents and emulsi- fying agents 3& l A% Distilled water and flavor- ing q.s.oz. 8 Flavoring only 7/10% Cobb's Pills. Extract of henbane gr. 30 Extract of conium gr. 30 Extract of colocynth gr. 40 Extract of nux vomica gr. 4 Mix, make a mass, and divide into 30 pills. — Contributed to D. C. Cocacaffeine. (105) This is a granular effervescent prepa- ration, each heaping teaspoonful of which contains 34 grain of cocaine and 1 grain of caffeine. Cocadrenine Suppositories. (115) Each suppository is stated to contain 16 minims of a 1% solution of adrenalin borate and Vs grain of cocaine hydro- chlorid. They are used for hemor- rhoids. Coca-Glycerite Suppositories. (83) These are stated to contain cocaine muriate, boracic acid, soduim sulfate, hamamelis virg., Hydrastis canad., gallic acid, eucalyptol and glycerin. Cocaine Carbolate (or Phenate). This is a viscid, yellowish mass, solu- ble in alcohol but insoluble in water. It is a local anesthetic, analgesic and anti- catarrhal, useful in dental operations, rheumatic pains, conjunctival, nasal, gas- tric and other catarrhs. Used in 1 to 3% solution in 30% alcohol, 5% powder, or pure. Dose: 1/12 to 1/8 gr. once or twice daily in capsules. In injections use in a 1 11250 solution in alcohol. Cocaine Formate. This is in white silky needles, soluble in 41 parts of .water. PROPRIETARY AND SYNTHETIC REMEDIES. 709 Cocapyrin. This is a mixture of I part of cocaine with ioo parts of antipyrin. It appears in the market in the form of 3-grain tab- lets which are intended for throat affec- tions. Coccia Pills. (182a) Each pill is stated to contain Aloes, purified gr. iYa Scammony resin gr. I Colocynth, powder gr. Yz Potassium sulfate gr. Ys Oil of clove m. Y& Cock's Anti-Phymin. See Anti-Phymin. Cocoaine. See Burnett's Cocaine. Coddington's Asthma Powder. A similar preparation may be made as follows (N. I.) : Potassium nitrate av.oz. I Anise, seed av.oz. I Stramonium leaves av.oz. I Lobelia leaves av.oz. I Codeine Cough Sedative. 159 Each fluidounce is stated to represent Codeine phosphate gr. I Ext. cannabis indica gr. Y2 White pine bark gr. 32 Wild cherry bark gr. 32 Yerba santa gr. 16 Balm of gilead buds gr. 4 Chloroform m. 2 Glycerin fl.dr. 2 Codliver Glycerine. (47) This is described as "a hydrated gly- cerized morrhuine," "a concentrated sol- uble morrhuine extract," "four times the medicinal strength of cod liver oil." Coe's Dyspepsia Cure. Rhubarb, powder dr. 2 Sodium bicarbonate ...dr. 6 Fluid extract of gentian fl.dr. 3 Peppermint water fl.oz. yY* — Nelson, from N. I. Coirre's Solution. Sodium phosphate gr. 343 Calcium chlorid sufficient Hydrochloric acid . . 10%, fl.dr: 6 Water, to make fl.oz. 16 Dissolve the sodium phosphate in 24 fluidounces of water and to this solution add either 183 grains of anhydrous or 365 grains of hydrous calcium chlorid. Collect the precipitate, wash it with wa- ter and dissolve it in the acid and enough water to make 16 fluidounces. Each ta- blespoonful contains 4 grains of acid calcium phosphate. — H. Colalin. (52) This is described by the manufactur- ers as "the amorphous active principle of bile." It is put up only in tablets, of which 1 or 2 are taken at a dose 3 or 4 times daily. It is used as a hepatic stimulant and for gall stones. Colalin Laxative. Each tablet is stated to contain colalin, % grain, extract of cascara, 2 grains, and podophyllin, 1/6 grain. Colchicine Salicylate Comp. Tablets. (116) These are stated to be composed of "thermol" and colchicine with pure nat- ural salicylic acid. Colchi-Sal. (Colchicine Salicylate Capsules, Trochet.) This is sold in capsules, each one of which contains Ya milligramme of col- chicine dissolved in 20 centigrammes of methyl salicylate (oil of wintergreen). It is also stated to contain "1/500 grain of the active principle cannabis indica." Coley's Mixture. (159) This is a preparation containing ery- sipelas and prodigiosus toxins prepared according to the formula of Dr. Coley of the New York Cancer Hospital. It is used for the treatment of inoperable malignant growths, particularly sarco- mata. It is injected in or near the tu- mor, beginning with ^ to 1 minim and increasing gradually. Within 3 weeks it may be told if improvement may be ex- pected from the treatment. Dr. Coley and others have reported a number of cures. Collaform. This is stated to be a formaldehyde- gelatin, intended as a vulnerary. Collargoi. (Soluble or Colloidal Sil- ver — Argentum-Crede.) This is a water-soluble, allotropic form of metallic silver, said to contain 710 THE STANDARD FORMULARY $5 to 87% of metallic silver and a small percentage of albumin with products of its oxidation. It occurs in small, hard, brittle, bluish-black, scale-like pieces, sol- uble in 20 parts of distilled water, pro- ducing a dark, olive-brown solution which remains stable for months. Xo separate silver particles can be distin- guished in the solution even when mag- nified to the highest degree under the microscope, and it has all the character- istics of a solution. The addition of al- bumin to collargol prevents or delays its precipitation by acids and salts. A suf- ficient amount of albumin to prevent its precipitation under ordinary conditions is therefore added to collargol during its manufacture. Hence, collargol, even when dissolved in well or spring water containing salts, undergoes no change, and it remains unaffected by boiling, whereas colloidal silver containing no albumin precipitates on being boiled. A solution of collargol does not respond directly to the tests for silver ; it should not be exposed to light or air; it is in- compatible with the usual silver reagents. Collargol is a general antiseptic and germicide which can be used externally or internally; it can be introduced into the system without causing either local reaction or general poisonous effects. In most cases it is best employed locally in the form of a 15% ointment, 30 to 60 grains being thoroughly rubbed into the skin. It is also used in 2 to 5% aqueous solutions for intravenous injections (in septicemia and pyemia), /> to 1% glyce- rin solutions for parenchymatous injec- tions; also in 1/50 to 1% solutions for washes, in 5% dusting powder, in bougies containing 3 grains, and in vaginal sup- positories containing 24 grain. Internal- ly a solution of 1:500 to 1:100 is given freely in teaspoonful doses; it is also given in pills or tablets containing J/3 to 1 grain. To prepare a solution of collargol, put the latter into a perfectly clean, amber- colored bottle, add the required amount of distilled water, and allow to stand until the collargol has softened, then shake vigorously until complete solution is effected. The solution should have a clear, brown color; if gray and turbid it is decomposed. Collargol Ointment. (Unguentum Crede.) This contains 15% of collargol. It is prepared by incorporating 15 parts of collargol with 5 parts of water, 10 parts of white wax and 70 parts of benzoin- ated lard, observing care that the soluble silver shall not be transformed into or- dinary metallic silver, which it is prone to do unless great care be exercised. The natural color of this ointment is dark bluish-gray. The addition of water may change the color to a brownish shade, which does not, however, impair its efficiency: The ointment is good as long as it colors the skin black. This ointment is used for inunction, from 30 to 60 grains being rubbed into the skin for 15 to 30 minutes. For chil- dren about one-half as much should be used. Collas' Capsules of Iron. According to Hager, these contain iron reduced by means of electricity in- stead of iron reduced by hydrogen. Collaurin. (Colloidal Gold.) This is used in syphilis, cancer and scrofulous conditions in doses of y 2 to 1 grain. Collins' Disinfecting Powder. Chlorinated lime, dry parts 2 Burnt alum part 1 — N. I. Colorless Hydrastis. (131) This is described as a permanent so- lution of the white alkaloid of Hydras- tis. The menstruum is said to be neu- tral and non-irritating. Colsaloids. (187) These are described as containing 1/250 grain of colchicine in 3 minims of methyl salicylate. PROPRIETARY AND SYNTHETIC REMEDIES. 711 Colsathyl. (84) This is described as a 5-minim cap- sule containing colchicine (1/160 gr.), phenol and methyl salicylates. It is rec- ommended for rheumatism, gout, sciat- ica, etc. Col-Solules. (89) These are soft capsules containing 1/250 gr. of colchicine and 3 m. of methyl salicylate. Col-Solules with Salol contain in ad- dition 2 gr. of salol. Compound Alum Powder. (184) A mixture of dried alum, carbolic acid and camphor. Compound Lithia Tablets. (160) Each tablet is stated to contain lith- ium carbonate, sodium bicarbonate, po- tassium bicarbonate and magnesium sili- cate in proportion to yield about 6 grains of lithium citrate, 6 grains of potassium citrate, 3 grains of sodium citrate and 1 grain of magnesium silicate. Compound White Pine Pectoral. (198) Each fluidounce is stated to contain 30 grains each of white pine and wild cherry, 4 grains each of balm of gilead buds and spikenard, 3^ grains of blood root, 2 grains of sassafras bark, 4 min- ims of chloroform and 3/16 grain of morphine acetate. Condy's Fluid Disinfectant. This is an English proprietary prepa- ration used as a disinfectant, said to contain manganaie and permanganates of the alkalies and other salts, the na- ture of which does not appear to have been accurately determined. A solution of potassium permanganate (1%) offi- cial in the British Pharmacopoeia is in- tended to replace it. Coniine Hydrobromid. (Conicine or Cicutine Hydrobromid.) This is the salt of an alkaloid derived from Conium maculatum. It is in white prisms or in powder, soluble in 2 parts of water, 2 of alcohol, also soluble in ether and chloroform. It is used as an antispasmodic and antineuralgic in tetanus, sciatica, etc. It has recently been lauded in whooping-cough. The dose for children is 1/600 to 1/40 grain 2 to 4 times daily, for adults 1/30 to 1/15 grain 3 to 5 times daily. Hypoder- mically in tetanus as much as 1/20 to 1/6 grain have been injected. Antidotes are first, emetics to evacuate the stom- ach, then tannin or an astringent tinc- ture or fluid extract, and finally atro- pine, strychnine, picrotoxin and stimu- lants as systemic antidotes. Conklin's Salve. Resin av.oz. 12 Yellow wax av.oz. 1 Mutton suet av.oz. 1 — Contributed to D. C. Controdolin. This is described as a "combination of salicylic and phenylic acids with ace- tamide." It is recommended as an an- algesic and antipyretic in doses of 5 to 10 grains. Convallamarin. This is a glucoside from Convallaria majalis. It is a yellowish powder, solu- ble in water and alcohol, insoluble in chloroform, almost insoluble in ether. It is a powerful noncumulative heart tonic, like digitalin, and is also diuretic. Dose : ^ to 1 grain every 1 or 2 hours. Maximum dose : Single, 1 grain; daily, 5 grains. Convallarin. This is not to be confounded with convallamarin, but both are derived from the same plant. It is a yellowish- white powder, soluble in alcohol, but in- soluble in water. It is a purgative, with- out cardiac action. Cook's Electro-Magnetic Liniment. Alcohol fl.oz. 64 Oil of amber fl.oz. 4 Camphor av.oz. 4 Castile soap, fine av.oz. 1 Ox gall, fresh fl.oz. 2 Ammonia water fl.oz. 6 — Kilner. Corassa Compound. The following formula has been given by A. B. Lyons as the result of an an- alysis : 712 THE STANDARD FORMULARY Gentian per cent I5 Licorice root percent 15 c§? r per cent 50 Sodium bicarbonate percent iyy 2 Cochineal percent 2^ Cordial Analptine. (167) Each tablespoonful contains sodium iodid, 1/10 grain, lithium salicylate, 2 grains, potassium acetate, 5 grains, ex- tract of black cohosh, "3 minims," and extract of cascara sagrada, "3 minims." It is used for rheumatic affections. Cordial Exalginique. (121) This is stated to contain 2 l / 2 grains of exalgine in each teaspoonful. Cordial Pas-Carnata. (131) This is stated to contain all the ac- tive medicinal constituents of Passiflora incarnata in concentrated form. Cornutine Citrate. This is the salt of an alkaloidal prod- uct, which according to Kobert, is the true active principle of ergot. It is a brownish-black mass or powder, very hygroscopic, soluble in alcohol, sparing- ly and incompletely soluble in water. It is used for the same purposes as ergot, to promote labor pains, as a hemostatic, etc. As a hemostatic it is used in doses of 1/8 grain 3 times daily. It has also been advocated for sperma- torrhea in doses of 1/20 grain twice daily. Cornutol. (141) This is described as a concentrated, aseptic preparation of ergot of rye, es- pecially prepared for hypodermic 'and general use. It is 2^ times as active as fluid extract of ergot, U. S. P. It is furnished in i-ounce vials and in her- metically sealed bulbs each containing V2 dram. Corpula. (119) According to the manufacturers this "does not contain a drug, or drugs, in the strict sense of the term. In a broad sense, the phosphates of grain, the dias- tase of malt, the maltose of malted grain, lactose from milk, and the small amount of flavoring principles present, might be said to constitute a mixture of drugs, but this is not true in any specific sense, as none of these have a specific therapeutic action other than that of concentrated foods, or aids to digestion of other amylaceous foods." Corrective Mixture. (160) This is described as a very desirable neutralizing cordial indicated in acid stomach, flatulency, children's diarrhea, and the constipation of infants. It is stated to contain magnesium hydroxid combined with "aromatic rhubarb." Cortexalin. (50) This is stated to contain gentian, co- lumbo, cinchona rubra, damiana, nux vomica, and Burgundy wine. Coryfin. (Ethylglycolic Ester of Menthol.) This is a limpid, colorless, oily sub- stance of faint odor of menthol. It is soluble in alcohol, ether and chloroform. It is applied locally for catarrh and coryza. When applied to the forehead it causes the cooling feeling of menthol which lasts for an hour. In cases of cold in the head the nasal mucous mem- brane may be painted with corypin and marked relief in breathing is said to be obtained. Cosaprin. (Sodium Acetylsulfani- late.) This is a white, crystalline substance freely soluble in water, less soluble in alcohol. It has been introduced as a substitute for acetanilid. The dose is 10 to 30 grains. Cotarnine Hydrochlorid. See Stypticin. Cotarnine Phthalate. See Styptol. Coudray's Eau de Quinine. According to Hisserich in the Berlin Pharm. Ztg., this has the following com- position : Tincture of cinchona fl.oz. 1 Tincture of cantharides. . .fl.dr 4 Spirit of soap fl. oz . 2 Cologne water fl. oz . 5 Alcohol fl.oz. 5 PROPRIETARY AND SYNTHETIC REMEDIES. 713 Peru balsam gr. 192 Oil of bergamot fl.dr. i l / 2 Oil of sweet orange fl.dr. \ x /z Oil of rose geranium drops 30 Brandy, to make fl.oz. 40 Cochineal enough to color Cough Tablets. (108) Each is stated to contain ammonium chlorid, cubeb, wild cherry, terpin hy- drate and licorice. Cram's Fluid Lightning. Contributed by I. L. Fulton to W. D. : Oil of mustard, volatile. .. .fl.dr. 1 Oil of cajeput fl.dr. 1 Oil of clove fl.dr. 1 Oil of sassafras fl.dr. 1 Ether fl.dr. 4 Tincture of opium fl.dr. 6 Alcohol fl.oz. 10 By some it is supposed that this prep- aration is merely a solution of volatile oil of mustard in alcohol. Crealbin. This is a compound of creolin and albumin containing 50% of the former. It is a brown powder used as an intes- tinal astringent and antiseptic in doses of 5 to 15 grains. Cream of Cod Liver Oil. (140) This preparation is stated to contain 67% of pure cod liver oil, predigested with pancreatin, and gum arabic to im- part consistency. Cremoline. (207) This is described as an emulsion of animal and vegetable fats, this being the formula : Cream 50% Cod liver oil , 25% Olive oil 3% Hennessey brandy 6% Syrups and aromatics 16% Creoferrate Elixir. (179) This preparation is stated to contain peptonates of iron and manganese and beechwood creosote. Creolin. There are two varieties of this article, known as Pearson's and Artman's. Both are made from crude cresol, the former being a resin soap emulsion, the latter is obtained by treating the crude cresol with sulfuric acid. — Coblentz. Creosal. See Tanosal. Creosin. This is a clear yellow liquid, of not unpleasant taste, soluble in water, misci- ble with wine, soup, milk, etc. It is stat- ed to contain iodin, creosote, calcium hypophosphite, and peru balsam. It is an Italian product, used in phthisis. Creosotal. (Creosote Carbonate.) This is prepared by passing a current of carbonyl chlorid into a solution of creosote in sodium hydroxid and puri- fying the oily product by washing with weak soda solution and then with water. It is a yellowish, thick, honey-like, per- fectly clear and transparent liquid, con- taining 92% of creosote. It is odorless and has a bland oily taste. It is insolu- ble in water but soluble in alcohol, ether, chloroform and fixed oils. It is incom- patible with alkalies. It has the same medicinal action as creosote but is claimed to be non-toxic and non-irritant. It is recommended as a substitute for creosote for. internal ex- hibition in tuberculosis, pneumonia, and as an intestinal antiseptic. The dose for children is 5 to 30 grains, for adults, 15 to 60 grains, in milk, coffee, wine, cod liver oil, or emulsion. Externally it may be applied undiluted. Creosote Capsules, Sommerbrodt's. These are prepared according to Prof. Sommerbrodt's formula, each capsule containing 2 minims of creosote "with suitable cod liver oil vehicle." Creosote Carbonate. See Creosotal. Creosote Iodid. See Creosotide. Creosote Mixture Comp. See Mixture Creosote Compound. Creosote Oleate. See Oleocreosote. Creosote Phosphate. See Phosote. ;i i THE STANDARD FORMULARY Creosote Phosphite. Phosphotal. Creosote Salicylate. See Salocreol. Creosote Tannate. See Tanosal. Creosote Valerianate. See Eosote. Creosotide. (Creosote Iodid.) (143) This is stated to be a combination of iodin and creosote, containing about 25% of iodin. It forms a brownish powder ui weak creosote odor and taste, and in- soluble in water. It is recommended for tuberculosis, scrofula, obstinate rheumatism, some cases of asthma, etc. It is put up in H-gr. and l A-gr. tablets, also in combination tablets with pepsin, bismuth or strychnine. Creosotonic (Scott). (58) F.ach fluidram is said to contain Guaiacol { represented by- Creosote \ soluble sulfonates, each m. 1 Quinine hypophosphite _ gr. 1/36 Strychnine hypophosphite ..gr. 1/256 Sodium hypophosphite^ gr. 1/5 Potassium hypophosphite ...gr. 1/5 Iron hypophosphite gr. 1/5 Calcium hypophosphite gr. 1/8 Manganese hypophosphite . .gr. 1/8 Oil of turpentine m. i^4 Iodin gr. 1/16 Phenol gr. ^4 Combined with aromatic oils in the form of a perfect emulsion and using elixir of lactated pepsin as a vehfcle. Creo-Terpin Comp. (211) Each fluidounce is stated to contain Creosote m Terpin hydrate gr Calcium glycerophosphate . . . .gr Sodium glycerophosphate ....gr in hydrochlorid gr It also cointains 26% of alcohol. This is used for colds, phthisis, asth- ma, catarrh, pneumonia, etc.. in doses of from 1 to 2 teaspoonfuls every 1 to 3 hours. Cresalol. (Cresol Salicylate— Cresol Salol.) This is a whitish powder, insoluble in 4 4 8 4 1/6 water, but soluble in alcohol and ether, used as an intestinal antiseptic and as a dusting powder. Dose : 5 to 30 grains daily. There are three cresalols. ortho, meta and para-cresol salicylates, the para compound being generally employed. Cresobene Capsules. (59) Each capsule is stated to contain Beech wood creosote gr. 2 Terebene gr. 1 Eucalyptol gr. l / 2 Quassin gr. 1/65 They are recommended for phthisis, bronchitis, asthma, etc. Cresol Iodid. (Traumatol.) This is a compound of cresylic acid and iodin. It is a yellowish, very bulky powder, containing 54% of iodin. It is insoluble in water, soluble in alcohol, ether, chloroform and fixed oils. It ad- heres to the hands, instruments, etc., like resin. It is used as an antiseptic in place of iodoform. Crethol. (155) This is described as an alkaline sa- ponaceous cresylic acid compound, con- taining orthocresol. It is a clear brown liquid of a cresol odor. Croton-Chloral Hydrate. See Butyl-Chloral Hydrate. Crurin. (Quinoline-Bismuth Sulfo- cyanid.) This is a reddish-yellow powder of a slight quinoline odor, insoluble in alco- hol and water. It is marketed as a 50% dusting powder mixed with starch. It is used as a dusting powder for ulcers of the leg, also for gonorrhea in mix- tures containing y 2 % with wat^r and a little glycerin. Cryogenine. Chemically this is metabenzaminose- micarbazide, a white, odorless powder, soluble in 40 parts of water, more solu- ble in alcohol, ether and chloroform. It has been recommended as an antipyretic in phthisis and typhoid fever in doses of 5 to 15 grains. PROPRIETARY AND SYNTHETIC REMEDIES. 715 Cryostase. This is said to consist of equal parts carbolic acid, camphor and saponin, with traces of oil of turpentine. It becomes solid when heated, and liquid below o° C. It has been recommended as an anti- septic. Crysol. This is an antiseptic preparation (not proprietary) made according to this for- mula : Crude carbolic acid parts 5 Resin soap part 1 Liquid soda soap parts 4 Liquid soda soap is made from: Cottonseed oil av.oz. 10 Sodium hydrate av.oz. i l / 2 Alcohol fl.oz. 8 Water fl.oz. 12 Crystallose. This is a name given to a very soluble sodium salt of saccharin. It is stated to be 400 times sweeter than sugar. Cupricitrol. (Copper Citrate.) This is a greenish powder, very slight- ly soluble in water. It is used in 5 to 20% dusting powders and ointments in diseases of the eye, particularly tra- choma. Cuprohemol. (Cuprated Hemol.) (130) This is hemol with 2% of copper in organic combination. It is prepared by precipitating a solution of blood with a dilute neutral solution of a copper salt at a temperature not materially exceed- ing o° C. It is a dark-brown insoluble powder, said to be useful in tubercu- losis, scrofula, anemia, chlorosis, etc. The dose is iH to 3 grains 3 times daily. The maximum dose is 8 grains. Cuprol. (Copper Nucleinate or Nuc- leide.) (159) This is stated to be a chemical com- pound of copper and nucleinic acid con- taining about 6% of the former. It is a green powder, soluble in water. This has fte advantage over other copper salts in that it penetrates tissues more deeply and is less irritating to inflamed surfaces. Its solutions do not coagulate albumin and are not precipitated by al- kalies. It is employed pure or in 10% solutions as an antiseptic and astringent, chiefly in eye diseases. Curarine. (Tubocurarine.) This is the alkaloidal principle oi cu- rare or woorari, the South American arrow poison. It differs from all other crystallizable alkaloids, with one excep- tion of containing no oxygen. It is in colorless crystals which are extremely deliquescent, of extreme and persistent bitterness; it is soluble in water s and al- cohol. It has been recommended in tetanus, in doses of 1/60 to 1/12 grain used hypodermically. Antidotes are at- ropine, strychnine, artificial respiration and stimulants. Curaril. This is represented to be a stable, very active liquid preparation of- curare, and is used for tetanus. It is used hypo- dermically in doses of 2.4 cc. If after one-half hour, no effect is observed, the dose is repeated every two or three hours, each dose being increased by 0.2 cc, until relief is obtained. Curwin's Hog Powder. According to Caldwell, this consists of salt, sulfur, copperas and charcoal. The sulfur estimated 4.33%, the iron sulfate 4.55%, the sodium chlorid 77-74%, and the carbon 3.53%.— Era, 1889. Cutal. (Aluminum Borotannate.) This is a light-brown powder, insolu- ble in water excepting on the addition of tartaric acid. It contains 76% of tan- nin, 13.23% of aluminum and 10.71% of boric acid. It is used externally as an astringent and antiseptic in skin dis- eases. With tartaric acid it forms soluble cutal or aluminum borotannicotartrate, which is used in solution in some skin diseases, in gonorrhea, etc. Cypri-Bromides. (83) Each fluidounce is stated to represent 60 grains each of cypripedium and po- THE STANDARD FORMULARY tassium bromid, 15 grains each of so- dium and ammonium bromids, 15 min- ims of deodorized tincture of opium, 2 grains of "brom. caffeine," and aromat- ics. CypridoL. (204) This is put up in capsules, each one containing 20 centigrams. It is describ- ed as "a 1% solution of nascent bin- iodide in an aseptic oil." Elsewhere it is stated that a capsule is equivalent to 1/32 grain of mercuric iodid. Cystopurin. This is a double salt of one molecule of hexamethylene-tetramine and two molecules of sodium acetate. It is a white powder, very soluble in water but almost insoluble in alcohol. Daffy's Elixir. (Tincture of Senna Compound. Various formulas have been given for this, among which is the following: Alexandria senna, cut dr. 8 Jalap, finely powdered dr. 4 Coriander dr. 2 Raisins, deprived of seeds. av.oz. V/2 Diluted alcohol fl.oz. 16 Macerate for 7 days, shaking occa- sionally, and filter. Dalby's Carminative Elixir. This is an old English patent which is said to be a mixture of Tincture of asafetida g, Tincture of opium g Tincture of castor g Oil of peppermint g Oil of caraway g Alcohol g Simple syrup g Calcined magnesia g 10 20 30 10 5 100 150 5 -H. In a somewhat modified form, this is now recognized by the N. F. under the name Carminative Mixture. Dallmann's Tamarinden Essenz. The following is the formula of the Muenchener Apotheker Verein for tam- arind essence : Tamarinds (not the ex- tracted pulp) av.oz. 10 Senna leaves, cut av.oz. 1 Magnesia, calcined gr. 18 Simple syrup fl.dr. 6 Syrup of orange fl.dr. 6 Sryup of cinnamon fl.dr. 6 Alcohol fl.oz. 1 Distilled water, Magnesium carbonate, each sufficient Upon the tamarinds pour 50 fluid- ounces of hot distilled water, mix thor- oughly, macerate for several hours, and strain without pressure through a hair sieve.* Evaporate the product until it weighs 20 av. ounces, and neutralize 15 av. ounces of this with magnesium car- bonate. Also macerate the senna and calcined magnesia with 10 fluidounces of distilled water (cold) for 24 hours, strain with- out pressure, add the tamarind extrac- tive, heat the whole to boiling, strain through flannel, and evaporate the liquid to a weight of 16 av. ounces. To this when cool add the syrups and the alco- hol previously mixed with 3 fluidrams of water, set aside for some time, and filter. Damn olid. This is a preparation of hemoglobin intended for the treatment of anemia of cattle. It comes in three forms. Dam- holid liquid containing 40% of hemoglo- bin ; damholid I, a dark brown, granular, odorless powder, readily soluble in 8 parts of cold water; and damholid II, a fine brownish-red powder, also soluble in 8 parts of water. Daniel's Conct. Tinct. Passiflora, (56) This is described as a concentrated tincture prepared from the green leaves, fruit and root of the may-pop (Passi- flora incarnata). It is used in nervous irritability, especially in insomnia. Daniel's Pineapple Phosphates. The ingredients are stated to be soda, lime, iron, phosphorus, extract of wild cherry, and calisaya bark. It is recom- mended for chlorosis in doses of a tablespoonful 3 times a day. Darby's Prophylactic Fluid. Potassium permanganate ...gr. 5 Potassium sulfate gr. 150 Potassium carbonate av.oz. i$4 PROPRIETARY AND SYNTHETIC REMEDIES. 717 Potassium chlorid gr. no Water, to make fl.oz. 16 — Fenner. Darpin. (166) This is the name given to "dark pinus canadensis." Darwin's Liniment. Oil of wormwood fl.oz. I Oil of thyme (red) .fl.oz. I Stronger water of ammonia. fl.oz. i Wood alcohol fl.oz. 13 Davy's Urinal Cakes. (Disinfecting Solid.) A mixture of resin with sulfates of copper, iron, zinc and sodium and some alum. These salts are probably pow- dered and mixed with the resin by fu- sion.— O. J. Bierbach, in Oregon Phar. Asso. Day's Kidney Pad. Black cohosh av.oz. Gum benzoin av.oz. Gum guaiac av.oz. Juniper berries av.oz. Queen-of-the-meadow av.oz. Digitalis : .av.oz. Oil of juniper fl.oz. Reduce the solids to moderately fine powder and incorporate. Make into an oblong pad to wear over the kidneys. Dehaut's Purgative Pills. Aloes gr. 100 Jalap root gr. 100 Gamboge gr. 50 Extract of dandelion sufficient Make into pills each weighing 2 grains. — H. Delabarre's Sirop de Dentition. This is similar to a mixture of Tincture of saffron m. 10 Tincture of ipecac... m. 10 Syrup of rhubarb fl.oz. 1 Syrup of licorice fl.oz. 1 According to some, it also contains vanilla. — H. Dental Surprise. This contains about lH% of cocaine hydrochlorid and some carbolic acid. — Sadtler. Dentalone. (159) This is the name given to a saturated solution of chloretone in a mixture of oils of clove, cassia and wintergreen. These oils are stated to take up over 30% of their weight of chloretone, hence the solution is a very active local anes- thetic — one that is especially suitable for application to exposed nerves in decay- ing teeth. Dentalone is also used for the treatment of sensitive dentine, pain- ful and inflamed tooth- sockets, etc., and as a solvent for arsenic paste. Derby Liniment. Linseed oil fl.oz. 16 Ammonia water fl.dr. 4 Tincture of capsicum fl.dr. 1 Oil of origanum fl.dr. 1 — Kilner. Deret's Bi-Iodized Elixir. This is stated to be composed of Sweet wine liter 1 Mercury iodo-tannate g. 9.5 The quantity of mercury contained in one tablespoonful is stated to be equiva- lent to y 2 centigram (1/12 grain) of "bi-iodide." Dericin. See Floricin. Derival. This is said to be a mixture of spirit of mustard, ammonia and oil of turpen- tine, recommended as an application for rheumatism. Dermamol Ointment. (143) Among the ingredients mentioned are carbolic acid, resorcin, tar, bismuth sub- carbonate, and zinc oxid. Dermasapol. This is a medicinal soap basis, con- sisting of a mixture of oil, fat, lanolin and paraffin, together with alkalies in sufficient quantities for complete saponi- fication. It is used in combination with various drugs in diseases of the skin, and as a fatty vehicle for the adminis- tration of remedies through the cutane- ous surface. Dermatin. This is a new skin perfecting prepara- tion consisiting of from 5 to 7 parts salicylic acid, 7 to 15 parts starch, 25 to 50 parts talcum, 30 to 60 parts silicic acid, and 3 to 9 parts of kaolin. 718 THE STANDARD FORMULARY Dermatol. (Bismuth Subgallate.) An odorless saffron-yellow powder, containing 55 r c of bismuth oxid. It is non-irritant and non-toxic externally; insoluble in water, alcohol, ether or chloroform ; an antiseptic in wounds, burns, eczemas, ulcers, etc. It is used as a substitute for bismuth subnitrate internally in gastro-intestinal affections; externally it is used like iodoform. Dose : 30 grs. daily. Dermogen. This is a pale yellowish, odorless in- soluble powder stated to contain 40 to 6oTr of zinc peroxid; it is stated to give off oxygen on contact with wounds and thus act as a stimulant and disinfectant. Deshler's Salve. According to X. I., this is similar to Compound Resin Cerate, U. S. P., 1870, which is prepared as follows : Resin av.oz. 4 Suet av.oz. 4 Yellow wax av.oz. 4 Gum turpentine av.oz. 2 Linseed oil fl.oz. 2% Melt the wax, suet and resin, add the turpentine and then the oil, strain and stir until cool. Detergal. (182a.) This is described by the manufactur- ers as a non-poisonous liquid antiseptic soap. Dethan's Pastilles of Potassium Chlorate. According to Hager, they are made as follows : Potassium chlorate gr. 150 Carmine gr. 1 Tragacanth gr. 15 Tincture of tolu m. 15 Sugar av.oz. 3 Orange-flower water sufficient Mix and divide into 100 oval lozenges. Dewee's Tincture of Guaiac. Resin of guaiac gr. 960 Potassium carbonate gr. 45 Pimento, moderately fine powder gr. 240 Pumice powder av.oz. 1 Alcohol fl.oz. 7 Water fl.oz. 7 Diluted alcohol, to make. . .fl.oz. 16 Triturate the resin and potassium car- bonate with the pimento and pumice, and afterward gradually add the alco- hol. Next add the water, triturate the mixture thoroughly, filter, and pass enough diluted alcohol through the filter to make 16 fluidounces. Dextroform. This is described as a condensation of dextrin and formaldehyde. It is white, almost inodorous and tasteless, soluble in water and glycerin, insoluble in alcohol. It is used as an antiseptic application to wounds and as an injec- tion for gonorrhea in 2 l / 2 to 5% solu- tions. Dextro-Quinine. This is said to consist of quinidine with other alkaloids after the extraction of quinine from red cinchona. — Fenner's Form. Dextro-Saccharin. Saccharin part 1 Glucose, crystal, .parts 1000 to 2000 — B. Fischer. Diabetin (Levulose — Fruit Sugar — Fructose.) (178) This is a pure, crystallized levulose, free from dextrose (ordinary glucose). It is colorless, odorless, slightly hygro- scopic, of a sweet taste like cane sugar, readily soluble in water and diluted al- cohol. It is recommended for the nutri- tion and for sweetening the food and drink of diabetics, in pulmonary tuber- culosis, infantile nutrition, and maras- mus. It is given in diabetes in daily quantites of 1 to 2 ounces, in grave forms of the disease the amount is re- duced to from 3 to 6 drams. Diacetyl-Morphine. See Heroin. Diaphtherin. (Oxyquinaseptol.) This is a yellow crystalline powder, soluble in water and diluted alcohol. It is used as a surgical antiseptic. Diastase. For the various brands of diastase mentioned in this book, see Bana-Dias- tase, Diastin, Taka-Diastase, and Vera Diastase. PROPRIETARY AND SYNTHETIC REMEDIES. 719 Diastin. This is a brand name for vegetable diastase. Diathesin. This is a name given to saligenin pre- pared synthetically instead of by de- composition of salicin. It is fine, white leaflets of a slightly bitter taste, soluble in 15 parts of cold water, freely soluble in hot water or alcohol. It is employed in place of salicylates in the treatment of rheumatism, neuralgia, tonsillitis, gout, etc. It is said to be more palatable and readily administered than sodium salicylate and not to excite the disgust caused by the latter, nor to cause ring- ing in the ears. The dose is 7^2 to 15 grains 3 or 4 times a day. Diazyme Essence. (70) This is a liquid which is stated to contain the amylolytic enzyme of the pancreas, devoid of trypsin and lipase in a menstruum containing i&A % of alco- hol by volume. It is capable of digest- ing starch and is said to be useful to compensate for deficient pancreatic se- cretion. Diazyme Glycerole. This is a liquid stated to contain the myalolytic enzyme of the pancreas, de- void of trypsin and lipase, in a men- struum composed of about 60% of gly- cerin by volume. Dick's Wonder Salve. According to Hager, this is of the same composition as camphorated moth- er plaster. Dickson's Improved Anaesthetic. This contains 4% of cocaine hydro- chlorid with some carbolic acid and chloral hydrate. — Sadtler. Didymium Salicylate. See Dymal. Diethylbarbituric Acid. This is the chemical name for veronal, which see. Difluordiphenyl. This is a white crystalline powder of pleasant aromatic odor, insoluble in wa- ter, soluble in alcohol, ether, chloroform and oils. It is used as an antiseptic dusting powder mixed with 9 parts of talcum, or in 10% ointment with lanolin as a dressing for burns. It is used in- ternally in bronchial affections in doses of 1/16 to % grain. In the form of a 5% ointment it is used under the name Antitussin (which see) for whooping- cough. Digalen. This is put up only in packages of l A ounce each. It is a clear brownish liquid stated to contain digitoxin in the sol- uble form made by Cloetta's process. Each cc. is stated to contain 0.3 mg. of soluble digitoxin. Digestiva Pills. (212) These are stated to contain each Concentrat. pepsin gr. 1 Nux vomica gr. V\ Sulfur gr. Yz Gingerine gr. 1/16 They are recommended for indiges- tion. Digestive Hypophosphites. (160) This is stated to be composed of the hypophosphates of calcium, potassium, iron and manganese with 1 grain of quinine sulfate and 1/16 grain of strychnine sulfate dissolved in a fluid- ounce of glycerole of pepsin and pan- creatin, the whole being flavored; no sugar is used. Digestol. (10) This is stated to be a mixture of bis- muth subnitrate, pepsin, extract of gin- ger, salol, milk sugar and cinnamon water. Digitalin Comp. Elixir. See Elixir Digitalin Compound. Digitalone. (159) This is sterile, non-alcoholic, non- irritating, permanent preparation of digi- talis, equivalent in strength to a 10% tincture of digitalis. It may be admin- istered hypodermically as well as by mouth. It is preserved with 0.6% of chloretone and its subcutaneous injec- tion is comparatively free from pain. 720 THE STANDARD FORMULARY Digitoxin. This is the most active glucosicle from digitalis. It is a white crystalline powder, soluble in alcohol and chloro- form, slightly soluble in ether, insolu- ble in water. It is a powerful heart tonic. Dose: 1/250 to 1/125 grain 3 times daily. As an enema, give 1/80 grain 1 to 3 times daily. The maximum dose is 1/32 grain daily. The so-called "soluble digitoxin" made by Prof. Cloetta's process is which is chemically and theapeutically identical with the other digitoxin but is fairly soluble in water. Diiodof orm. (Tetraiodoethylene.) This is an antiseptic which may be regarded as the condensation product of 2 molecules of iodoform with the elim- ination of 1 molecule of hydriodic acid. It contains 96.7% of iodin (almost as much as iodoform), is said to therapeu- tically equal to the latter, and is almost odorless. It is in yellowish needles, in- soluble in water, slightly soluble in alcohol and ether, but more soluble in chloroform and carbon disulfld. Dionin. (Ethyl-Morphine Hydro- chloride This is a white powder, odorless and only slightly bitter, soluble in 7 parts of water and 2 parts of alcohol. It is claimed that this compound acts like morphine without producing constipa- tion, nausea or lassitude. It is recom- mended to relieve pain, especially in respiratory affections, as an antispas- modic in whooping cough, for insomnia, and externally in the treatment of cor- neal affections, conjunctivitis, iritis, etc. The dose is ^4 to 1 grain. Externally it is applied in 10 to 20% solutions. Diosmal. This is an extract of buchu prepared by a special process, viz.: Exhausting the buchu leaves with boiling ligroin and then with boiling alcohol. Dioviburnia. (64) This is stated to contain the fluid ex- tracts of wild yam, star grass, black haw, cramp bark, squaw vine, helonias, blue colosh and scullcap. It also con- tains 18% of alcohol. It is a uterine tonic and antispasmodic. Dioxogen. (152) This is the trade name for the Oak- land Chemical Co.'s brand of hydrogen peroxid. Dipsomania Tablets. (17) The tablet triturates consist of Gold and sodium chlorid gr. l /$ Cocaine hydrochlorid gr. 1/6 Ammonium muriate — gr. 1/16 Strychnine nitrate gr 1/50 Atropine sulfate gr. 1/200 The hypodermic tablets consist of Gold and sodium chlorid gr. 1/10 Strychnine nitrate gr. 1/40 The tablet triturates and hypodermic tablets are to be used together. Diphthericide. This is in pastilles containing thymol, sodium benzoate and saccharin. They are used as a prophylactic against diph- theria. Diphtheritic Powder. (Pulvis Diph- theriticus.) (60) This is stated to contain Calcarise silicatse. Calcariae sulphuratae. Potassae sulphuratae. Potassae chloratae. Pulvis aromatic, q. s. Dipthero Comp. Elixir. See Elixir Diphthero Comp. Dispnon Tablets. Each tablet is stated to contain 0.25 g. of diuretin, 0.10 g. of agurin, and 0.10 g. of extract of quebracho. They are em- ployed for asthma and shortness of breath. The dose is 2 tablets 3 times a day. Diurazin. (116) This is stated to be chemically theo- bromine acetylmethylenedisalicylate. It is said to contain 30% of theobromine and 55% of salicylic acid. It is recom- mended for dropsical conditions in doses of 6 grains every 2 hours. PROPRIETARY AND SYNTHETIC REMEDIES. 721 Diuretic Oil Capsules. These sre recommended by Prof. Ko- bert as a substitute for various diuretic teas. They contain o.i g. of each of the following: Juniper oil, lovage oil, an- gelica oil, jaborandi oil, apiol, safrol, guaiacol, terpinol, and borneol. Diuretin. (Theobromine-Sodium Salicylate.) This is a white, odorless powder of a saline taste and containing 50% of theobromine, and 38% of salicylic acid. It is freely soluble in water but ex- posure to the carbon dioxid of the air renders it insoluble and hence it must be preserved in glass-stoppered bottles. It is incompatible with many other chemicals and hence should be pre scribed by itself. It has the same medi- cal properties as theobromine over which it has the advantage of greater solubility. The dose is 15 grains given 5 or 6 times daily. Diurol. (Elixir Serenqse Comp.) (141) Each fluidounce is stated to contain Lithium benzoate gr. 4 Potassium bicarbonate gr 8 Buchu gr. 8 Couch grass gr. 16 Saw palmetto gr. 16 Hydrangea gr. 16 Corn silk gr. 16 Pichi gr. 16 Sandalwood gr. 2 Henbane gr. 1 Belladonna gr. y 2 This is described as an alkaline diure- tic which exerts a soothing and tonic influence upon the genitourinary tract and relieves vesical and renal irritation. Dixon's Pills. Compound ext. colocynth . . . . gr. 240 Rhubarb gr. 120 Tartar emetic gr. 8 Syrup of buckthorn sufficient To make 120 pills. — Cooley. Doan's Backache Kidney Pills. According to an analysis reported in the British Medical Journal, the follow- ing furnishes a similar product : Oil of juniper drop 1 Potassium nitrate gr. 5 Hemlock pitch gr. 10 Fenugreek gr. 17 Wheat flour gr. 4 Corn starch gr. 2 Divide into 20 pills. Doan's Dinner Pills. According to an analysis reported in the British Medical Journal, these have approximately the following composi- tion: Oil of peppermint drops 1 Podophyllin gr. 3.8 Aloin gr. 6.9 Jalap resin gr. 0.8 Capsicum gr. 0.5 Licorice, powder gr. 0.6 Extract of henbane gr. 1.5 Acacia gr. 1.5 Corn starch gr. 0.5 Dodd's Kidney Pills. According to an analysis reported in the British Medical Journal, these were found to consist of extract of cascarilla, jalap resin, soap, potassium nitrate, so- dium bicarbonate, paraffin, turmeric and wheat flour. Dolomol. (165) This is magnesium stearate, containing small amounts of magnesium palmitate and oleate. It is a white powder, in- soluble in water, unctuous to the touch, nearly odorless and tasteless. Its mag- nesium content corresponds to nearly 7% MgO. Acting as a protective to the skin it is recommended in cutaneous affections as a dusting powder, alone or mixed with various remedies. It is marketed plain and mixed with acet- anilid, boric acid, salicylic acid, alum, iodoform, resorein, thymol, sulfur, tar, etc. Doloran Tablets. These are used as an anesthetic in teeth extraction 1/10 mg. of adrenalin. 10 mg. of cocaine and 2 mg. of sodium chlorid in each capsule. Dormiol. (Amylene Chloral.) This is a combination of amylene hy- drate and chloral hydrate. It is an oily, colorless liquid of a camphoraceous odor, insoluble in cold water but freely miscible with alcohol, ether, chloroform and oils. It is marketed in 50% solu- 722 THE STANDARD FORMULARY tion and in capsules. It is used as a hypnotic in doses of 5 to 30 minims. Dorsenia. This is a dental anaesthetic contain- ing about l/5% of cocaine hydrochlor- ate with some carbolic acid, camphor, and probably alcohol.— Sadtler. Dow's White Liquid Physic. This is made of the following: Sodium sulfate av.oz. 4 Alum gr. 30 Xitromnriatic acid fl.oz. 1 Distilled water fl.oz. 12 Driffield Oils. This is prepared by boiling olive oil with fresh wormwood, savin and arnica, and adding about 1/60 part of a mix- ture of oils of rosemary, thyme and juniper. — H. Duboisine Sulfate. This is a yellowish, hygroscopic pow- der soluble in water. It is used as a sedative and hypnotic, especially in men- tal diseases, also as a mydriatic like atropine, but is much stronger; it is used principally as a mydriatic in aque- ous solution, each fluidounce to contain y 2 to 2 grains of alkaloidal salt. Dose: 1/160-1/64 gr. 2 to 3 times daily. Maximum dose : single, 1/32 gr. ; daily, 1/16 gr. Antidotes: Pilocarpine, muscarine. Duffy's Cathartic Elixir. This contains, it is claimed, jalap, senna, buckthorn, anise, caraway, cori- ander and galangal. Dulcin. (Sucrol.) This is a sweetening agent similar to saccharin, being said to be 300 times sweeter than cane sugar. It is a white, less powder, soluble in 25 parts of alcohol, 50 of boiling water and 800 of cold water. It is used for the same purposes as saccharin. Dunbar's Serum. See Pollantin. Duo-Peptonate. (Liquor Ferri et Mangani Peptonatus.) (142) Also called Duothal. Each tablespoon ful is stated to con- tain approximately Peptonate of iron gr. iV 2 Peptonate of manganese gr. % Duotal. (Guaiacol Carbonate.) This is an odorless, crystalline pow- der, containing 913/2% of guaiacol, is insoluble in water, slightly soluble in glycerin, alcohol and oils. It is used as an intestinal antiseptic, and is given in phthisis. Dose: 8 to 15 grains. It is pre- ferred to guaiacol and creosote because it does not disturb the digestive func- tions. Duothal. This is another name for Duo-Pep- tonate, which see. Duotonol. (178) This is a mixture of equal parts of calcium and sodium glycerophosphates (or calcium tonol and sodium tonol — See Tonols). This is a white, granu- lar powder, freely soluble in water. It is used as a nerve tonic in doses of 5 to 10 grains 3 times daily. Dupuytren's Pills. Each is made to contain Guaiac, powder gr. 3 Opium, powder gr. ^ Corrosive sublimate gr 1/10 Dupuytren's Hair Pomade. Beef marrow av.oz. 3^ Peru balsam dr. 1 Oleobalsamic mixture m. 50 Tincture of cantharides m. 25 Oil of cinnamon m. 30 Oil of bergamot m. 15 — H. Duran. This is a combination of calcium car- bonate and phosphate with egg-albumen, in the form of a white powder; it is also put up in chocolate-coated tablets. It is said to be useful in children's com- plaints, particularly rickets and similar ailments. Dusal. See Sal-Eliminant. Dusart's Syrup. A French proprietary preparation consisting essentially of syrup of lacto- phosphate of lime flavored with orange flower water. PROPRIETARY AND SYNTHETIC REMEDIES. 723 Dyche's Compound Capsules of Guai- acol No. 1. Each capsule contains 5 minims of guaiacol, 10 minims of cod-liver oil, and K gr. of codeine. Dyche's Compound Capsules of Guai- acol No. 2. Each capsule contains 5 minims of guaiacol, 10 minims of cod liver oil and Yz gr. of iodin. Dyche's Compound Pills of Potassium Iodid. Each pill contains 5 grains of potas- sium iodid and 1/20 grain of red iodid of mercury. Dymal. (Didymium Salicylate.) This is a fine starch-like, reddish- white, odorless powder. It is a valu- able drying antiseptic. It is applied in the form of powder or as a 10% oint- ment in various skin diseases, notably dry and weeping eczemas, impetigo, herpes, prurigo, etc. Dynamyne. (118) This is preparation which contains the alkaloids of tobacco. It is a green-col- ored hydroalcoholic liquid, which was used largely by the late Prof. A. J. Howe. It is applied when diluted to re- lieve pain, either deep-seated or super- ficial. It is not adapted for internal use. — American Dispensatory, new edition. Dyspepsia Fermentative Tablets. (141) Each tablet is stated to contain Salol gr. Y^ Zinc sulf ocarbolate gr. ^ Extract of nux vomica gr. 1/6 Creosote gr. J / 2 Betanophthol gr. 3/10 Bismuth subnitrate gr. ^ Bismuth subgallate gr. 1 Bismuth salicylate gr. 1% Oil of clove q. s. Dyspepsyn. The formula is given as follows : Saccharated pepsin gr. 10 Saccharated pancreatin gr. 5 Acid lactophosphate of lime..gr. 5 Exsiccated extract of malt equal to 1 teaspoonful of liquid ext. of malt gr 10 46 Easy Physic. (89) This is described as compound lico- rice powder compressed into lozenges. Eau de Fees. This is a hair preparation which is a solution of 5 parts of lead sulfite in about 12 parts of sodium hyposulfite, 31 parts of glycerin, and 352 parts of water. — H. Eau Figaro. This is a solution of lead sulfate or acetate with sodium hyposulfite and some glycerin. — H. Echafolta. (118) This is a concentrated liquid prepara- tion of the plant echinacea. It is prac- tically colorless and odorless. It is highly praised as an antiseptic and tonic- alternative in septic conditions, such as carbuncles, erysipelas, ulcers, abscesses, wounds, etc. It is applied externally in a 25% solution with water and intern- ally it is given at the same time in doses of 2 to 5 drops. Echino. (65) A plastic compound. This is the de- scription : "Each pound contains kaolin, 2220; sulph, 960; combined with arnica, bryonia, echinacea, eucalyptus oil, lo- belia, boracic acid, oil gaulth, glycerine, q. s. ad." Echinol. (131) This is a concentrated liquid prepara- tion of echinacea, which is stated to be ten times the strength of the crude drug, and is designed for the conveni- ent manufacture of ointments and other compounds of echinacea intended for local application. Echitone. (190) This is stated to represent the fol- lowing drugs in the fresh condition : Echinacea angustifolia gr. 180 Viola tricolor gr. 180 Iris versicolor gr. 30 Aromatics. The total amount is not stated. It is recommended for the internal treatment of eczema. '24 THE STANDARD FORMULARY Echthol. (19) This is described as an antipurulcnt containing the active principles of echinacea and thuja. It is recommended for carbuncles, boils, typhoid fever, ery- sipelas, abnormal cell growths, and pus formations. A teaspoonful is adminis- tered 3 times a day and it is also used externally. Eczemacide. (181) This is stated to be composed of "thymenthol," glycerin and nitric acid, with 15 grains of acid nitrate of mer- cury to each pint. Eczemarol. (135) This is stated to be composed of acet- anilid, resor-cin, zinc oxid, ichthyol, oil of cade, and pyroligneous acid with a lanolin base. Eczemol. (76) This is stated to be a mixture of anti- septic oils, hydrocyanic acid, nitric acid, mercury bichlorid, and glycerin. Edison's Polyform. This is the formula according to the specifications of English patent: Chloral hydrate g. 30 Camphor g. 60 Oil of peppermint drops 5 Oil of clove drops 5 Morphine sulfate g. 2 Amvl nitrite g. 3 Salicylic acid g. 5 Ether g. 50 Chloroform g. 90 Alcohol g. 1 10 Egeriol. (217) This is described as an antiseptic al- kaline solution containing menthol, eu- calyptol, thymol, gaultheria, baptisia, boric acid, and aromatics. Egg Emulsion of Cod Liver Oil Im- proved. (159) This is stated to contain 40% of pure cod liver oil combined with nutrients, egg and brandy. Egmol. (159) This is described as a 40% emulsion of olive oil. Egyptian Eye Salve. This is said to be composed of the following (X. I.) : White resin Burgundy pitch Yellow wax Mutton suet Venice turpentine Balsam of fir. . . . .av.oz. 12 .av.oz. 1 .av.oz. 1 .av.oz. 1 .av.oz. 1 . av.oz. 1 Eigons. (62) The eigons are a group of bromin and iodin compounds of albumin. They are designed to take the place of the iodids of •potassium, sodium and am- monium and of bromid of potassium. The following eigons are described in this book, viz. : Brom-Eigon, Iodo- Eigon, Iodo-Eigon Sodium, Pepto- Brom-Eigon, and Pepto-Iodo-Eigon. Eikonogen. This is a chemical largely used for photographic purposes. Eka-Iodoform. (178) This is described as a pure iodoform prepared by electrical synthesis and ster- ilized with 1/20% of paraform (solid formaldehyde). Ektogan. This is a mixture of zinc hydroxid and dioxid containing about 50% of each and is equivalent to about 8% of active oxygen. It occurs as a yellowish- white, odorless, tasteless and insoluble powder. It is used externally in wounds and in skin diseases in the form of a moist dressing mixed with citric, tartaric or tannic acid whereby oxygen is liberated. With iodids it develops iodin.— Ph. Post. Elchina. This is a compound cinchona elixir stated to contain 0.32% of quinine, 2% of sodium glycerophosphate and 1% of tincture of nux vomica. Mixed with wine and in some cases with 3% of hy- drochloric acid it is considered use- ful in dyspepsia and some weakened conditions of the system. PROPRIETARY AND SYNTHETIC REMEDIES. 725 Electric Headache Cures. These all consist essentially of an alcoholic solution of essential oil of mustard, which is usually sprinkled on a small tuft of cotton inclosed in a wide-mouthed bottle. The twisted wires in these bottles are placed there simply to delude a gullible public. Electrozone. (37) This is the way this "wonderful" preparation has been described in ad- vertisements : Antiseptic, germicide, disinfectant, non-toxic, non-irritant. A product of electricity made from sea- water and containing compounds identi- cal with the solids of the blood. Na CIO, Mg Cl 2 2 , K CI 0, K Br O, Na 10, etc. These compounds are liberated by the process of electrolysis and held in solution. Etc., etc. Elepizone. This is composed of about the follow- ing: Magnesium bromid dr. 3 Sodium bromid dr. 3 Water . ... .' fl.oz. i l / 2 Oil of cassia drops 2 Simple syrup, to _ make fl.oz. 4 Solution of carmine to color — N. I. Elixir Anti-Dyspeptic. (Elixir Pep- sin and Thymol Comp.) (221) Each dessertspoonful is stated to con- tain 1 grain each of pepsin and cascara sagrada, 2 grains of pancreatin, % grain of ipecac, 1/60 grain of strychnine with the active constituents of 30 minims of "antiseptic solution." Elixir Aphrodisiac. (207) Each fluidounce is stated to represent 30 grains each of damiana and saw palmetto, 20 grains each of coca and kola, and 1 fluidram of diluted phos- phoric acid. Elixir Bromides Comp. (141) Each fluidounce is stated to contain 20 grains each of the bromids of strontium, sodium and ammonium in combination with 20 minims of tincture of henbane and 1 fluidram of tincture of valerian. It is used for various forms of nervous irritability. Elixir Cascanata. See Cascanata. Elixir Chloralamid. (115) Each fluidounce is stated to contain 15 grains of chloralamid. It is considered a safe and efficient hypnotic. Elixir Chlor-Lactated Pepsin. (160) Each fluidounce is stated to contain: Sac. pepsin, U. S. P., 1880... gr. 160 Sac. pencreatin gr. 5 Hydrochloric acid gr. 3 Lactic acid, U. S. P., 1880. . .gr. y 4 For the powder, see Chlor-Lactated Pepsin. Elixir Chloro-Calcium. (182a.) This is stated to contain 40 grains of pure calcium chlorid to the fluidounce. Elixir Creoferrate. See Creoferrate Elixir. Elixir Digitalin Compound. Each fluidram is stated to contain 1/100 grain each of digitalin and nitro- glycerin and 1/50 grain of strychnine sulfate. Elixir Piphthero Comp. (60) This is the formula as printed by the manufacturers : Liquor naphthalini purific, Liquor guaiacoli, Oleoresina? pini alpanienis (alpine pine), Muscarini, Baptisini and elix. aromat., q. s. The same company also puts up a Pulvis Diphtheriticus, which see. — W. D. Elixir Eupnein. (179) Each dose of 2 fluidrams is stated to contain 1/24 grain of heroin, 2 grains of terpin hydrate, 5 grains of creosote, in a menstruum containing 30% of alcohol with glycerin and aromatic essential oils. Elixir Galega-Vera. (35) This is stated to contain the active principles of Galega officinalis, G. teph- rosia and G. apolinea. Elixir Guaiacol Co. See Triacol. Elixir Halogens Compound. (188) Each fluidram is stated to contain 9 grains of the combined iodids, bromids THE STANDARD FORMULARY and chlorids of calcium, magnesium, so- dium, potassium and iron with "com- pound cxt. sarsaparilla" and suitable aromatics. See also Elixir Iodide and Bromide of Calcium Compound. Elixir Heroterpine. (Elixir of Her- oin and Terpin Hydrate.) (179) Each fluidounce is stated to contain 1/6 grain of 'heroin and 8 grains of ter- pin hydrate. The preparation also con- tains $2 r, c of alcohol with glycerin and aromatic essential oils. Elixir Iodide and Bromide Calcium Compound. (192) Each fluidram is stated to contain to grains of the combined iodids, bromids and chlorids of calcium, potassium, so- dium, iron and manganese with com- pound syrup of sarsaparilla, laxatives and aromatics. See also Elixir Halogens Compound. Elixir Iodo-Bromide of Calcium Comp. (Elixir Iodo — Tilden's.) (194) This is the formula as given on the label : Each fluidounce contains 72 grains of the combined salts of bromin, iodin, chlorin, calcium, magnesium, iron, sodium and potassium, not chemically united but held in solution, together with I ounce of the combined constituents of stillingia, sarsaparilla, rumex, dulcamara, lappa, taraxacum and menispermum. There is also an Elixir of Iodo-Bro- mide of Calcium Comp. with Mercury, 1 fluidram of which contains 1/100 grain of mercury bichlorid. Elixir Lactenzyme. (63) Each teaspoonful is stated to contain 5 grains of "lactenzyme powder," which see. Elixir Lactenzyme with Phosphate of Iron, Quinine and Strychnine is stated to contain in each teaspoonful Lactenzyme gr. 5 Iron phosphate gr. 1/2 Quinine^ phosphate gr. 1/2 Strychnine phosphate gr. 1/128 This preparation is a valuable nerve tonic and restorative. Elixir Lactopeptine. (145) Each fluidounce is stated to represent 38 grains of "lactopeptine." Elixir of Lactopeptine with Gentian and Chloride of Iron. Each fluidounce is stated to represent Lactopeptine gr. 32 Gentian gr. 8 Protochlorid of iron gr. 8 Elixir of Lactopeptine with Phos- phate of Iron, Quinia and Strychnia. Each fluidounce is stated to represent Lactopeptine gr. 32 Phosphate of iron gr. 4 Phosphate of quinia gr. 4 Phosphate of strychnia gr. 1/16 Elixir Laxative Compound. (160) Each fluidram is stated to represent 5 grains sodium "sulph." (probably "sul- phate"), iY 2 grains each of leptandra and senna, ^2 grain each of licorice root and fennel seed, and 1/20 grain each of powdered belladonna leaf and nux vom- ica. Elixir Maltopepsine. See Maltopepsine Elixir. Elixir Nutrans. Each fluidounce is stated to represent Cocoa gr. 20 Kola nut gr. 20 Damiana gr. 30 Saw palmetto gr. 30 Fresh beef oz. 2 It is recommended as a vitalizing tonic to the reproductive system. Elixir Palmetto Compound. (192) This preparation is said to contain in each fluidram 8 grains of saw palmetto berries, and 4 grains of couch grass and sandalwood. Elixir Pancreo-Digestin. (188) Each fluidram is stated to contain 10 grains of "pancreo-digestin," which see. Elixir Pancreo-Digestin, Gentian and Chlorid Iron. Each fluidram is stated to contain 5 grains of "pancreo-digestin" with elixir of gentian and iron chlorid. Elixir Pancro-Pepsin. (181) Each fluidram is stated to represent 10 grains of "pancro-pepsin," which see. PROPRIETARY AND SYNTHETIC REMEDIES. Y27 Elixir Pepdilactic. See Pepdilactic Elixir. Elixir Pepsin and Thymol Comp. See Elixir Anti-Dyspeptic. Elixir Peptenzyme. See Peptenzyme Elixir. Elixir Peptopancreatine Compound. 192 Each fluidounce is stated to contain 40 grains of peptopancreatine compound, which see. Elixir Pinus Compositus. (Bechol.) 131 Each fluidounce is stated to contain White pine (fresh bark)...gr. 40 Wild cherry bark gr. 40 Spikenard gr. 5 Balm of gilead buds gr. 5 Sassafras gr. 4 Ipecac gr. 2 Ammonium chlorid gr. 4 Sanguinaria nitrate gr. 1/12 Morphine acetate gr. 1/2 Chloroform m. 4 This preparation is also put up with heroin or codeine instead of morphine. Elixir Piscidia Compound. (215) This is an utero-ovarian sedative and anodyne, which is stated to contain in each fluidram 8 grains each of blackhaw and golden seal and 4 grains of Jamaica dogwood. Elixir Purgans Aromatic. (117) Each teaspoonful is stated to repre- sent Rhamnus purshiana gr. 10 Cassia acutifolia (purif.) gr. 10 Euonymus atropurpureus gr. 8 Iris versicolor gr. 4 Hyoscyamus niger (leaves) .. .gr. 2 Aromatics, etc. Elixir Purgative. (181) Each fluidram or teaspoonful repre- sents 8 grains of cascara sagrada, 4 grains each of senna and wahoo, 2 grains each of blue flag and henbane, with aromatics. Elixir Rhei Kalinatus. (181) Each fluidounce is stated to represent 20 grains each of rhubarb and potassium bicarbonate, 10 grains each of golden seal, cinnamon and pancreatin, flavored with oil of peppermint. Elixir Salicylic Comp. (212) Each tablespoon ful is stated to con- tain 20 grains of salicylic acid, i T / 2 grain of potassium iodid, IJ4 gr. of cimicifuga and 1 drop of tincture of gelsemium. The circular also states that this prepa- ration has the advantages afforded by the combination of salicylic acid with soda in excess, thus forming a salt less corrosive and irritating. Elixir Saw Palmetto and Santal Com- pound. (159) Each fluidounce is stated to represent 120 grains each of saw palmetto berries and corn silk and 30 grains of sandal- wood. It is diuretic and is said to have a sedative action on the genito-urinary tract. Elixir Senecin and Viburnin. (Elixir Amenorrhea.) (160) This is stated to contain senecin, vi- burnin, caulophyllin, hydrastis, Pulsatilla and aromatics. It is used in amenorrhea and dysmenorrhea. Elixir Six Bromides. (208) Each fluidram is stated to contain 5 grains each of bromids of potassium and sodium, 3 grains of ammonium bro- mid, 1^2 grains of calcium bromid, Yz grain each of lithium and iron, with cannabis and aromatics. Elixir Six Iodides. (208) Each fluidram contains 1/125 grain each of arsenic and mercury iodids, 1/12 grain of iron iodid, 1/10 grain of man- ganese iodid, and 1 grain each of so- dium and potassium iodids with aro- matics. Elixir Three Chlorides. See Henry's Three Chlorides. Elixir Tonicum. (87) Each 10 minims is stated to represent Tincture of cinchona m. 4 Tincture of mix vomica m. 1 Tincture of ignatia m. 1 Tr. of German chamomile, .m. 1 Tincture of gentian m. 1/2 Tincture of columbo m. 1/2 Tr. of phosphorus gr. 1/300 Aromatics m. 2 THE STANDARD FORMULARY Elixir TJroformin Comp. (63) Each teaspoon ful contains Uroformin (hcxamethylene- tetramine) gr. 5 Potassium acetate gt". 5 Fl. ext. couch grass m. 4 Fl. ext. buchu _ gr. 5 Fl. ext. juniper berries gr. 4 Fl. ext. corn silk gr. 4 Hydrastoids, q. s. It is employed in diseases of the ure- thra, bladder and prostrate. Elixir Viburnum and Hydrastis Comp. (Uterine Tonic Sedative.) (221) Each fluidounce is stated to represent 40 grains of cramp bark, 30 grains of golden seal, 20 grains of Jamaica dog- wood and 10 grains of pulsatilla. This preparation is used in all kinds of pain incident to diseases of the sexual or- gans. Elixir Vigorans. (Sohn's "Wine Hy- pophosphites Comp.) (206) Each "fluidounce is said to contain Hypophosphite of calcium gr. 6 Hypophosphite of potassium. . .gr. 3 Hypophosphite of sodium gr. 3 Hypophosphite of iron gr. y 2 Hypophosphite of manganese, .gr. ^2 Hypophosphite of quinine gr. y 2 Nux vomica gr. 1 Adjuvants: wine and glycerin. Elliman's Royal Embrocation. The following is somewhat similar : Oil of turpentine fl.dr. 4 Oil of thyme fl.dr. 3 Oil of amber, crude fl.dr. 1 Soap gr. 130 Caustic soda gr. 10 Water, to make fl.oz. 16 —X. I. According to Hager, it consists of the whites of 2 eggs, about 50 g. water, 50 g. crude wood vinegar, 60 g. alcohol and 8 g. oil of turpentine. Elytrones. (Antiseptic Vaginal Sup- positories.) (131) Each suppository is stated to contain 75 grains of boroglyceride solution, 5 minims of "colorless hydrastis," 40 min- ims of "thymoline (equivalent)," y 2 grain of zinc sulfocarbolate, 2 grains of acctanilid, and enough gelatin. Formula B has the same composition with the ad- dition of 5 grains of'ichthyol to each suppository. Emol. This is a native magnesium silicate similar to talcum and to fuller's earth. It is used as a dressing for wounds. Emoleo. (Oleo-Stearate of Zinc.) (121) This is described as a semi-fluid prep- aration for use in the treatment of dis- eases of the upper respiratory passages. It is said to be non-irritating, easily ap- plied, and readily diffusible. It is sup- plied plain or in combinations with iodin, Peru balsam, sodium bicarbonate and carbolic acid, or camphor and menthol. Emollientine. (159) This is stated to be a combination of aluminum hydrate, carbolic acid, isarol, lead oxid, corrosive sublimate, and zinc sulfocarbolate. It is used in the treat- ment of burns, scalds, bruises, etc. Empyroform. (178) This is stated to be a condensation product of birch tar and formaldehyde. According to the patent specifications it is made by boiling birch tar with for- maldehyde solution and pouring the hot liquid into hydrochloric acid. When cold the solid mass is collected and washed until free from acid. It forms a gray- ish-brown, almost odorless powder, in- soluble in water but soluble in acetone and chloroform. It is an antipruritic, sedative and de- siccant. It is said to be superior to tar and free from irritant or toxic effects. It is claimed to be useful in all stages of eczema, psoriasis, lichen, urticaria, pru- rigo, pityriasis, etc. It is applied as a 5 to 10% ointment, 10 to 20% zinc paste, 10 to 20% tincture or Z7 l A7o suspension. Emulgates. This is a name given to what may be termed "solid emulsions," these being triturations of oils, oleoresin of male fern or other similar preparations with equal parts of roborat (lecithalbumin). The products are dry, light and rather PROPRIETARY AND SYNTHETIC REMEDIES. 729 pleasant tasting. A number of these preparations have been put on the mar- ket, such as castor oil, cod liver oil emul- gate, male fern emulgate, copaiba emul- gate, etc. Emulgen. This is an emulsifying agent which is stated to be composed of tragacanth, 10, acacia, 5, gluten, 5, glycerin, 20, alco- hol, io, and water, 50. One part will emulsify 5 parts of cod liver oil. Emulsine. (133) Emulsol. (45) Both of these are emulsifying agents put up for the easy emulsification of oily substances. Endermol. (51) This is stated to be a "compound of stear-amide with hydrocarbons of the paraffin series" (stear-anilide with petro- latum?). It is an ointment base which is stated to be miscible with all drugs, holding them in a very fine divided state, the mixture being readily absorbed. Endometritis Tablets. (141) Each tablet is stated to contain Ext. viburn. prunif gr. 2 Ext. hamamel. virg gr. 1 Ext. nux vomica gr. 1/12 Ergotin gr. 1/2 Hydrastin, resin gr. 1/16 These tablets are recommended for inflammation of the uterus and its lining membranes. Enesol. (Mercury Salicyl- Arsenate.) This is stated to be made by the com- bination of equal parts of basic mercury salicylate and methylarsenic acid. It is a white powder soluble in 25 parts of water. It contains 38% of mercury and 14% of arsenic, is said to be less irritat- ing and less toxic than either of its con- stituents, and is used hypodermically for syphilis. Eno's Fruit Salt. According to N. I., this contains prac- tically the following : Rochelle salt parts 55 Tartaric acid parts 75 Sodium bicarbonate parts 84 Enterol. This is a name given to a mixture of the three isomeric cresols and is recom- mended as an enteric antiseptic. In so- lutions of 2% it is said to be non-toxic in doses of from 1 to 5 grams daily. The substance has the unpleasant odor and caustic effects of the cresols and is therefore advised that when used it should be administered in the form of pills or capsules. Enteronol. This is the formula as it is given : "Ipecac, sub. nit. bismuth, latalia rad., camphor, lupulin, caffein, and rheum." Enzymol. (70) This is a mixture of enzymes used as a physiological and surgical solvent. It is stated to dissolve septic matter, false fibrinous membrane, corrects offensive odors, etc. Eosote. (Creosote Valerianate.) This is a yellowish, oily liquid, insolu- ble in water, readily soluble in alcohol and ether. It is used mostly in phthisis. The dose is 3 to 10 minims 3 times in capsules or in milk. Ephredine Hydrochlorid. This is an alkaloidal salt derived from the leaves of Ephedra vulgaris. It is in white, needle-shaped crystals, soluble in water. It is used as a mydriatic in 10% solutions. Epicarin. This is a condensation product of cre- osotinic acid and betanaphthol, recom- mended by Dr. Kaposi for many skin affections. It forms colorless or yellow- ish needles, sparingly soluble in water, readily in alcohol, ether, acetone and soaps. It has the character of a strong acid, forming well crystallized salts, which, however, are sparingly soluble in water, particularly the sodium salt. On exposure to air, it acquires a reddish color, due to oxidation. Being a strong acid it is incompatible with alkaline hy- droxids or carbonates, especially those of sodium with which it forms an al- most insoluble salt. 30 THE STANDARD FORMULARY Epicarin is a non-poisonous antiseptic and parasiticide. Administered internal- ly it is excreted mostly undecomposed. It has been found useful in the treat- ment of skin diseases, particularly scab- ies, tinea tonsurans, prurigo and some forms of eczema. It is used externally in the form of a 5 to 20% ointment with petrolatum or wool fat or in the form of a 10% oily or alcoholic solution. Epidermin. This is an ointment vehicle consist- ing of equal parts of white wax, glyce- rin, acacia and water. Rub the acacia with the glycerin and water to a smooth paste, warm to 65 C, add the wax, pre- viously melted, and stir until cold. A white, sticky mass is obtained which, when treated with 50% of water, gives a white emulsion. Epinephrin. This is the name given by Prof. J. J. Abel of Johns Hopkins University to the active constituent of the suprarenal glands. Epiosin. This is said to be a derivative of mor- phigenin, and occurs in glistening pris- matic crystals, soluble in water, alcohol and chloroform. It is analgesic and hypnotic, but is also slightly toxic and must be administered with care. The dose is 1 to 2 grains. Epirenan. This is stated to be a sterilized 1 :iooo physiological salt solution of the chlorid of the purified active principle of the suprarenal bodies. Ergaloids. (89) These are elastic capsules, each con- taining Apiol, green m. 5 Ergotin gr. 1 Oil of savin m. 1/2 Oil of rue m. 1/2 Aloin gr. 1/10 Ergo-Apiol. (183) This occurs as elastic capsules, each one containing Apiol (special) gr. 5 Ergotin . . gr. 1 Oil of savin gr. y 2 Aloin gr. y§ The apiol (special) is stated to be made by a new process, "not the almost inert complex concentration" known by this name. Ergone. (159) This is described as a pure, concen- trated and aseptic extract of ergot, cor- responding in strength to the U. S. F. fluid extract. It is said not to contain ergotinic or sclerotic acid or other irri- tating substances. Ergot Aseptic. This is a preparation of ergot of dou- ble the strength of the U. S. P. fluid ex- tract of ergot. Ergotinic acid is stated to be eliminated and the finished prod- uct is sterilized. No preservative is add- ed. It is put up in glass bulbs of 1 cc. each and is intended for hypodermic administration. Ergotin. This is a name now commonly applied to soft solid extract of ergot, such as the U. S. P. extract of ergot. Ergotin-Styptic. This is stated to be fluid extract of ergot combined with 5% of stypticin. It is administered in from 10 to 15 drop doses in cerebral disturbances and in the neuroses accompanying menstrual dis- orders. Ergotole. (182a.) This is said to be 2}/ 2 times the strength of the U. S. P. fluid extract of ergot. It is stated to be free from inert, irritating and nauseating constituents. It may be administered hypodermically or by mouth. Ernutin. (32) This is described as a preparation of ergot "containing the specific active prin- ciples, chief of which is the alkaloid er- gotoxine, in a state of purity, which up to the present time has never been ap- proached." It is put up for administra- PROPRIETARY AND SYNTHETIC REMEDIES. Ition by the mouth in i-ounce bottles and for hypodermic use in io-minim sealed and sterilized bulbs. The initial hypo- dermic dose is 5 minims. Erosan. This is described as a mixture of 10 g. of potassium sulfoguaiacolate, 0.3 g. of dionin, 5 g. of fluid extract of orange peel, 30 g. of distilled water and 105 g. of simple syrup. Erpiol. (Dr. Schrader.) (131) This is in capsules each containing 5 minims of apiol (green), 3 grains of gossypin (resinoid) and 1 grain of er- gotin (Bonjean's process). Erythrol. This is a double salt of bismuth iodid and cinchonidine hydroiodid. It is a brown-red powder, insoluble in water or alcohol. It is recommended for some forms of dyspepsia as a digestive and anodyne in doses of % to 1 grain 3 times a day. Erythrol Tetranitrate. Nitrate — Tetranitrol rin.) (130) This is obtained by the nitration of the tetratomic alcohol erythrite. It forms colorless crystalline scales, insol- uble in cold water, readily soluble in al- cohol. On percussion it explodes much like nitroglycerin. It is a vasodilator and antispasmodic like nitroglycerin. Its action is slower and more lasting; it begins in 15 min- utes and persists for 3 or 4 hours. It is recommended in angina pectoris and vascular diseases. Because of its ex- plosiveness it is marketed in the form of an alcoholic solution and as tablets, the later containing l / 2 grain each. One or two tablest are given every 4 to 6 hours. Erythrophleine Hydrochlorid. This is in yellowish, crystalline gran- ules, which are soluble in water. It has recently been lauded as a local anaes- thetic. It is slower, but more intense in action than cocaine. It is used in a 1/20 to 1/10% solution, 731 (Erythrol -Tetranit- Escatol. (118) This is a preparation which was used largely by the late Prof. A. J. Howe (eclectic) and is a mixture of salicylic acid, zinc chlorid and petrolatum. It is put up in three strengths, single double and quadruple, for different cases. It is used for various kinds of ulcers, sores of a cancerous character, fissures of the anus, etc. Esencia de Calisaya. (159) Each fluidounce is stated to represent 24 grains of standard cinchona calisaya bark. Esencia de Coca. (159) This is described as an agreeable li- queur representing in concentrated form the stimulating properties of coca leaves. Eserine. (Physostigmine.) This is in white, hygroscopic laminae, sparingly soluble in water, readily in al- cohol, ether and chloroform. It is a spinal depressant and antitetanic in trau- matic tetanus, tonic convulsions, strych- nine poisoning, etc., peristaltic stimulant in atonic conditions of the intestine, an- algesic in neuralgias, muscular rheuma- tism, etc., and myotic. Dose: 1/200-1/100 grs. 2 or 3 times daily. It is also used successfully as a veterinary remedy in the colic of horses and cows, etc. It is generally employed in the form of soluble salts, such as the sulfate or salicylate, particularly the for- mer, as it is quite soluble in water. Its physiological antidotes are atropine, chloral hydrate, artificial respiration and stimulants. Eserine-Pilocarpine. This is made by crystallizing together 1 part of eserine salicylate and 2 parts of pilocarpine hydrochlorid. It is a white powder soluble in water and alco- hol, and used hypodermically in the colic of horses in doses of 3 to 6 grains. Eserine Oil. This is a solution of eserine salicylate in olive oil. It is used for applications to the eyes. 732 THE STANDARD FORMULARY Eskey's Mercuricide Ointment. See Mercuricide Ointment. Eskay's Neuro Phosphates. This is described as "a liquid prepara- tion of a food-like form of phosphorus containing the glycerophosphates of strychnine, sodium and calcium. Espic Cigarettes. The formula, according to Trousseau, is as follows : Belladonna leaves parts 24 Henbane leaves parts 12 Stramonium leaves parts 12 Phellandrium leaves parts 4 Extract of opium part J/2 Cherry-laurel water sufficient The leaves, well-dried and free of their ribs, are cut up and mixed. The extract is dissolved in the cherry-laurel water and the leaves are uniformly dampened with this solution. The paper which is used in making the cigarettes is also previously washed in a maceration of the leaves above named in cherry- laurel water and carefully dried. These cigarettes are used for asthma, the pa- tients smoking one or two during an at- tack.— W. D. Essence of Pepsine. (70) This is described as a solution of the milk-curdling and proteolytic ferments of the gastric glands in a menstruum containing i2>]/ 2 % by volume, the solu- tion being prepared by direct extraction of the peptic glands of the stomach. Es- sence of pepsine has the action of both rennin and pepsin and is recommended by the manufacturers for preparing milk for ingestion and in cases in which pep- sin is indicated. Essence of Smoke. See Wright's Condensed Smoke. Essence of Vera Diastase. See Vera Diastase Essence. Ester-Dermasan. This is superfatted soap containing 10'; of salicylic acid and 10% of the salicylic esters of benzoyl and phenol. It is used externally in the treatment of rheumatism, about 5 to 10 g. to be ap- plied to the affected parts once or twice a day. Ethyl Bromid. (Brom-Ethyl — Hy- drobromic Ether.) This must not be confounded with ethylene bromid. It is a clear, colorless, volatile, inflammable liquid, of an odor and taste like chloroform, sp. gr. 1.45 and boiling at about 102 F. It is spar- ingly soluble in water, freely so in alco- hol, ether and oils. It should be kept from light and air as it becomes brown from liberation of bromin and should then not be used. It is employed as an anesthetic in minor surgery, anesthesia occurring within 1 minute and lasting only a few minutes unless*- repeated; 1 to 6 fluidrams is used by inhalation. In- ternally it is used as a nerve sedative in epilepsy, hysteria, etc., the dose being 5 to 10 drops. Ethyl Carbamate. See Urethane. Ethyl Chlorid. (Monochlorethane.) This is ordinarily a gas, but appears on the market as a compressed liquid contained in closed tubes. In these tubes it is a colorless liquid, boiling at 54' C, and very inflammable. It is used for local anesthesia in minor and dental sur- gery, the liquid being allowed to spray upon the parts when it soon produces intense local refrigeration. The tube from which the spray issues should be held at a distance of from 6 to 10 inches from the part to be anesthetized. Ethyl Iodid. (Hydriodic Ether.) This is a clear, colorless, non-inflam- mable liquid, sp. gr. 1.93, boiling at 158 C. It is nearly insoluble in water but freely soluble in alcohol and ether. It should be kept from light and air. It is used by inhalation, 10 to 15 drops sev- eral times daily, for asthma, chronic bronchitis, chronic laryngitis, etc., also internally in chronic rheumatism, scro- fula, secondary syphilis, etc., in doses of 3 to 9 m. Ethyl-Morphine Bvydrochlorid. See Dionin, PROPRIETARY AND SYNTHETIC REMEDIES. 733 Ethyl Salicylate. See Sal-Ethyl. Ethylene Bromid. (Dibromethane.) This should not be confounded with the relatively non-poisonous ethyl bro- mid. It is a slightly brownish, volatile liquid, very heavy (sp. gr. 2.189) of a chloroformic odor, insoluble in water; soluble in alcohol. It should be pro- tected from light. It is used as a nerve sedative, as in epilepsy, in doses of I or 2 minims 2 or 3 times daily, in capsules or emulsion. Ethylenediamine. (178) This is a substitution compound of ethylene and ammonia. It is a clear, colorless, thick liquid, sp. gr. 0.97, boil- ing at 117 C. without decomposition, and having a strong alkaline reaction, an ammoniacal odor, and a caustic taste. It is freely soluble in water; it dissolves albumin, even when boiled, very readily. Being a strong base, its incompatibilities are about the same as those -of sodium hydrate. It is said to be non-corrosive. It is recommended as an albumin solvent for the solution of false membranes in diph- theria and similar affections of the mu- cous membranes. It is said that this substance can dissolve pus corpuscles. It is recommended for use in the form of kresamine, which see. Ethylenediamine-Mercury Sulfate. See Sublamine. Ethylenediamine-Silver Phosphate. See Argentamine. Ethylenediamine-TrikresoL See Kresamine. Eubiol. This is a hemoglobin preparation oc- curring as a powder and a 50% solution. The powder is odorless, tasteless and soluble in cold water. Eucaine. Eucaine B, beta-eucaine, or more properly beta-eucaine hydrochlorid, is chemically benzoyl-vinyl-diacetonalka- mine hydrochlorid. It forms a white, crystalline powder, soluble in 20 to 30 parts of water at the ordinary tempera- ture, but more soluble in warm water, soluble in 25 to 30 parts of alcohol, pro- ducing neutral solutions which can be sterilized by boiling without change. The saturated aqueous solution gives no precipitate with mercuric chlorid, which distinguishes it from the alpha-eucaine salt. It is incompatible with alkalies and their carbonates. Beta-eucaine is a local anesthetic like cocaine, but weaker and devoid of the stimulant properties of the latter. It does not dilate the pupil of the eye nor does it contract the blood vessels as does cocaine. It has the advantage of stability, even on prolonged boiling. It may be used in all cases in which co- caine is indicated as a local anesthetic, especially in ophthalmology. It may be applied in a 2 or 3% solution to the eye, 5 to 10% solution to the nose and throat, and 5 to 10% ointment for hem- orrhoids. It is used frequently instead of cocaine in Schleich's method of in- filtration anesthesia. Eucaine A (alpha-eucaine), or more correctly alpha-eucaine hydrochlorid, is a different compound chemically from beta-eucaine; it is more toxic and more irritant than beta-eucaine and is used but little. It is used as a substitute for eucaine in general and minor surgery. It is soluble in 10 parts of water. Eucaine Lactate. This is a salt similar to beta-eucaine hydrochlorid; 119 parts of the lactate contain as much eucaine as 100 parts of the hydrochlorid. It is a white powder, very soluble in water. It is very effec- tive as a local anesthetic and is said to be non-irritating, hence it is preferred for the eye, ear, nose, throat, and in dentistry, and also in infiltration anes- thesia. Eucaloids. (23) This is a name given to gelatin cap- sules, each containing q minims of pure oil of eucalyptus. 73-i THE STANDARD FORMULARY Eucalypteol. (Eucalyptene Hydro- chlorid.) This is derived from oil of eucalyptus. It is in colorless, scaly, almost tasteless crystals of a camphoraceous odor. It b insoluble in water, but soluble in ether, choloroform and alcohol. This is used as an internal antiseptic, the dose being 15 to 25 grains. Eucalyptol. This is obtained from oil of eucalyp- tus, but is also identical with cajeputol, from oil of cajeput, and cineol, from oil of wormseed. It is a colorless li- quid, of camphoraceous odor. It is in- soluble in water, but soluble in alcohol, ether and oils. It is used externally as an antiseptic and rubefacient, by inhalation and spray in lung and bronchial affections, and in- ternally in doses of 5 drops in capsules or emulsion. Eucalyptus and Honey Compound. (36) This is stated to represent eucalyptus, blood root, white pine bark, balm of gilead buds, sassafras bark, and cumin seed with 2 minims of chloroform and % grain of morphine acetate to each fluidounce. The preparation also con- tains 10% of alcohol. Eucamul. (23) This is an emulsion of oil of eucalyp- tus containing glycerin and honey. Each fluidram contains 2 minims of oil of eucalyptus. Eucasin. This is a casein compound containing 95% of casein and 5% of water. It is prepared from cow's milk. It is recom- mended as a dietetic for convalescents, invalids, or persons afflicted with lung, stomach or kidney troubles. The dose is a tablespoonful 2 to 4 times daily in soup. Eucodeine. (Codeine Brommethy- late.) (172) This is said to have the same sedative properties as codeine without the latter's tendency to induce clonic convulsions. It is a crystalline powder, soluble in wa- ter, and is used in the treatment of bronchitis and phthisis in doses of l /z to l A grain. Eucol. (84) Described as 20-minim capsules con- taining cod liver oil, beechwood creo- sote, eucalyptol, oil of santal and cubebs. They are recommended for bronchitis, colds, consumption, etc. Eucresyl. (143) This is a reddish-brown antiseptic li- quid stated to contain 50% of cresylic acid. Eudermol. (Nicotine Salicylate.) This is in colorless crystals soluble in water and alcohol. It is used as a 1/10% ointment for scabies and as a 1% oint- ment in veterinary practice, as for sar- coptic mange. It should not be con- founded with endermol. Eudoxin. (Tetraiodphenolphtalein- Bismuth.) This is the bismuth salt of nosophen, containing 53% of iodin and 14 1 A% of bismuth. It is an odorless, tasteless, in- soluble, brownish powder. It is used in stomachic and intestinal troubles in doses of 3 to 8 grains. It is especially useful in infantile diarrhea in doses of J / 2 to 1 grain. It is said to be non-toxic. Euformol. (159) Each fluidounce is stated to contain Oil of eucalptus m. 3/8 Oil of wintergreen m. 3/10 Thvmol gr. 1/2 Menthol gr. 1/12 Boric acid gr. 12 Fluid ext. wild indigo m. \Y\ Solution of formaldehyde, 40% m. 60 It is germicide, antiseptic, and deodor- ant. It is recommended for external ap- plication and for disinfection of excreta in infectious diseases. For genreal use it should be largely diluted. Eugallol. (Pyrogallol Monoacetate.) (109) This is a solution of 2 parts of mono- acetyl pyrogallol in 1 part of acetone. It - PROPRIETARY AND SYNTHETIC REMEDIES. 735 is a syrupy, dark yellow, transparent liquid of agreeable odor, readily soluble in water and acetone. It acts as an en- ergetic substitute for pyrogallol, but is liable to produce local irritation when applied to the skin. It is recommended for external use in old and persistent cases of psoriasis. It is applied pure by pencilling once a day, covering the paint- ed part with zinc oxid, suspending the application for a few days if followed by irritation. Eugenol. (Eugenic or Caryophyllic Acid.) This is a substance present in a num- ber of volatile oils, such as clove, pi- mento, cinnamon, sassafras and bay. It is an aromatic, colorless, oily liquid. It is almost insoluble in water, readily sol- uble in alcohol, ether and chloroform. It is a powerful antiseptic. It has been recommended in the treatment of tuberculosis in doses of K to I fluidram. Euguform. (Acetylated Methylene- Diguaiacol.) This is produced by the action of for- maldehyde upon guaiacol. It is a gray- ish-white, nearly odorless powder, in- soluble in water. It is used as a dusting powder, being recommended for abrad- ed surfaces in children, where the in- juries are so located as to be subjected to wetting. In the form of 5 to 10% ointment it is used for wounds, burns, etc. Soluble eugoform is a 50% solution of eugoform in acetone. Eukinase. This is a digestive ferment derived from the duodenum of the pig. It is a yellow powder which is marketed in the form of capsules which are not acted upon when swallowed until they pass the stomach. It is used in intestinal in- digestion. Eulyptol. (Ulyptol.) Carbolic acid part 1 Oil of eucalyptus part 1 Salicylic acid parts 6 — Schmelz. Eumenol. This is the fluid extract of a Chinese plant known under the names Tong-kui, Kau-kui, Schon-ki and Man-mu. It is an emmenagogue and uterine sedative in functional amenorrhea and dysmenor- rhea. The dose is a teaspoonful 3 times a day. Eumetra. (68) Each tablet is stated to contain Hydrastine gr. Yz Ext. henbane gr. y 2 Ext. wahoo gr. y 2 Ext. celery seed gr. Yz Ext. black cohosh gr. 1 Ext. black willow gr. 1 Ext. black haw gr. i$£ Ext. cannabis indica gr. 1/16 Capsicum gr. 1/8 Strychnine sulfate gr. 1/120 Socotrine aloes gr. 1/16 Excipient, q. s. It is used for uterine irritation, endo- metritis, etc. Emnydrin. (Methylatropine Nitrate.) It is a white, crystalline salt, odorless, permanent in the air, readily soluble in water or alcohol but sparingly in ether or chloroform; 100 parts of it contain the equivalent of 90 parts of atropine sulfate. It is incompatible with alkalies and their carbonates. Eumydrin is a mydriatic and antihy- drotic, replacing atropine sulfate both internally and externally in correspond- ing doses. It is claimed that it dilates the pupil more rapidly than atropine and the dilatation is of shorter duration — be- ing intermediate in these respects be- tween atropine and homatropine. It is said to be much less toxic than atropine so that larger doses may be given to se- cure the effect. It is particularly recom- mended for the treatment of night sweats, whooping cough and enuresis. Internally as an antihydrotic the dose is 1/60 to 1/24 grain. Externally it is used as a mydriatic in solutions about i/lO stronger than the usual atropine solu- tions. 736 THE STANDARD FORMULARY Eunatrol. (Sodium Acid Oleate.) This is a light yellow substance, read ily soluble in water and alcohol. It is supplied in the form of powder and chocolate-coated pills. It is recommend- ed in the treatment of gall stones, being an excellent cholagogue. The dose is 4 pills 3 times a day. Eupeptic Hypophosphites. (143) This is stated to be a combination of the hypophosphites of potassium, cal- cium, iron and manganese and the tonics quinine and strychnine, associated with the digestive ferments of the gastn'c juice. It contains wine as a vehicle; no sugar is added. Euphorin. (Phenyl TJrethane — Car- bamate of Ethyl and Phenyl.) This compound is closely related to urethane (ethyl carbonate, U. S. P.). It is in colorless needles or a white pow- der, having a faint aromatic odor and clove-like taste. It is almost insoluble in water, readily soluble in diluted al- cohol, alcohol or ether. It is an ano- dyne, antipyretic and antiseptic. It is recomended in rheumatism, sciatica, headache, etc. It is recommended ex- ternally as a dusting powder in venereal and skin diseases, ulcers, burns, etc. The dose is 8 to 15 grains, dissolved in wine or suspended in water. Externally it is used as a powder, in lanolin ointment, or in superfatted soap. It should not be confounded with europhene. Euphthalmine Hydrochlorid. (178) This is a mandelic acid derivative of beta-eucaine. It is a colorless, crystal- line powder, readily soluble in water and in 2 parts of alcohol. It produces prompt mydriasis free from anesthetic action, pain, or corneal irritation. It has little or no effect upon accommoda- tion. In its effects on the general sys- tem it closely resembles atropine. It is used in the form of a 2 to io9< solution, 2 or 3 drops of which are instilled in the eye. Eupnein Elixir. See Elixir Eupnein. Euporphin. (Apomorphine Methyl- bromid.) (172) This is colorless needles or scales, easily soluble in water or alcohol. It is intended to replace apomorphine especi- ally as an expectorant ; it is not so apt to produce vomiting in case of an over- dose. Its solutions are more permanent to light and air Eupyrine. This is a compound of paraphenetidin with vanillin ethyl-carbonate. It occurs as light yellow, needle-shaped crystals, tasteless, having a faint odor of vanillin, insoluble in cold water, sparingly soluble in warm water and in cold alcohol, read- ily soluble in warm alcohol, ether and chloroform. It is claimed to be a mild stimulating antipyretic, especially for patients with a weak stomach or other- wise sensitive. Dose, 8 to 15 grains. Euquinine. (Euchinin — Quinine Ethyl-Carbonate.) This is a light, fleecy conglomeration of delicate, white needles which are practically tasteless. It is sparingly sol- uble in water but readily soluble in alco- hol, ether and chloroform. It forms bitter salts with acids and should there- fore not be prescribed with acids as these develop the bitter taste. It is used in place of quinine on account of its tastelessness. It is said not to cause cinchonism nor to derange the stomach. The dose is the same as that of quinine. Eureka Dental Anesthetic. This contains 2>Va% of cocaine hydro- chlorid with some carbolic acid and oil of rose. — Sadtler. Euresol. (Resorcin Monacetate.) This is a thick, yellowish, oily liquid, of an agreeable odor and soluble in ace- tone. Its action is similar to that of resorcin but milder and more lasting be- cause of the gradual liberation of phenol. It is recommended for acne, sycosis, seborrhea and particularly in the treat- ment of chilblains. It is applied as a 5 to 20% ointment or as an acetone solu- tion. PROPRIETARY AND SYNTHETIC REMEDIES. 737 Euresol Soap. This is a soft soap, supplied in tubes and containing euresol, eucalyptol and oil of turpentine. It is used for chil- blains. Eurobin. (Chrysarobin Triacetate.) (109) ■ This is insoluble in water but soluble in chloroform, ether and acetone. It is used instead of chrysarobin and skin diseases in a i to 10% solution in ace- tone or with 5 to io% of saligallol. Europhene. (Di-Isobutyl-Cresol Io- did.) This is a product similar to thymol iodid. It is a yellow, voluminous pow- der, containng 28% of iodin and having a faint saffron-like odor. It is insoluble in water or glycerin but readily soluble in alcohol, ether, chloroform and the fixed oils. It is permanent in the dry state, but splits off iodin readily when moistened and rapidly when heated with water at 70 C, particularly in the pres- ence of alkalies. It should not be ex- posed to heat, light or damp air v It is incompatible with starch, metallic oxids, mercuric salts and alkaline hydrates and carbonates. Its action is similar to that of iodo- form and thymol iodid. It may be given internally in the form of pills in doses of 3 to 5 grains. Locally it is used as a dusting powder in substance or mixed with an equal quantity of finely pow- dered boric acid, as an ointment with wool-fat, or as a 5% embrocation dis- solved in olive oil. m Eusocopol. (172) This is the trade-mark name for chemically pure scopolamine hydrobro- mid, which is asserted to be entirely free from related alkaloids and impurities. For the production of scopolamine-mor- phine narcosis, 0.0012 g. (1/50 grain) of euscopol and 0.03 g. {]/ 2 grain) of mor- phine hydrochlorid are dissolved in 2 cc. of water. Such a solution is now mar- keted under the name scopomorphine. Eusemin. This is a preparation intended for hy- podermic use as a dental anesthetic. It consists of a mixture of adrenalin chlor- id solution (1:1000), 5, cocaine hydro- chlorid, 0.75, in normal salt solution, 100. — Phar. Jour., 1906. Eusoma. (Echinacea Compound.) (69) This is stated to be a liquid compound of Echinacea, Thuja and Baptisia. It is recommended as an antiseptic dressing in the treatment of wounds and skin diseass. Euthymol. (159) This is an antiseptic liquid which is stated to contain in each fluidounce oil of eucalyptus, Y% minim, oil of winter- green, 9/32 minim, menthol, 5/64 grain, thymol, 15/32 grain, boric acid, 10 15/16 grains, and fluid extract of wild indigo, i J /i minims. Euthymol Tablets. These are a combination of oil of eu- calyptus, thymol, boric acid, oil of win- tergreen, menthol and aromatics, to re- lieve mouth and throat irritations and purify the breath. Euzone. This is a trade name for pure sodium perborate (made by Schering). It is a white, odorless powder, containing about 7% of boron, 15% of sodium, 31% of oxygen, and 46% of water. It repre- sents 22% by weight of hydrogen dioxid. It is soluble in 10 parts of water, such a solution being equal to about a 2% solu- tion of hydrogen dioxid. The name Euzone is also applied to a preparation made by the Girard Chem. Co. This is an antiseptic and germicide liquid which is stated to contain lignol, eucalyptol, thymol, menthol, sodium bi- carbonate and benzoate, oils of winter- green and peppermint, glycerin and ex- cipients. Exalgin. (Methylacetanilid.) This occurs in colorless, acicular cry- stals, sparingly soluble in water, readily so in alcohol. It is an antipyretic simi- '38 THE STANDARD FORMULARY lar to antipyrine but the dose is smaller. It is prescribed as an antineuralgic in doses of 2 to 8 grains. Exarysis or Exhaustion Tablets. (160) These are stated to contain hypophos- phites of lime, soda, iron and manganese with quinine and nux vomica, associated with pepsin and pancreatin and made palatable with chocolate and vanilla. They are recommended as a digestive tonic and reconstructive. Exodin. (178) This is a mixture of derivatives of rufigallic acid, is therefore an oxyan- thraquinone derivative. It is a grenish- yellow, odorless, tasteless powder, insol- uble in water and sparingly soluble in alcohol. It is claimed to be a pleasant and reliable cathartic. It is said to pro- duce a mild and protracted tonic effect on the digestive tract and to produce neither gastric pains nor colic. It is claimed to be useful in acute and chronic constipation of the atonic form and also in cases in which regular evacua- tion of the bowels must be stimulated in consequence of hemorrhoids, etc. The dose for children is 7^ grains, for adults, 15 to 22 grains. This is not to be confounded with exodyne. Exodyne. Acetanilid parts 18 Sodium salicylate part 1 Sodium bicarbonate part 1 — Goldman's Analysis. Extract of Leeches. This is an aqueous extract from the heads of leeches hardened in alcohol, dried and powdered. The buccal secre- tion of the leech has the power of pre- venting coagulation of blood and this extract may furnish a means of effec- tively treating recurring thrombosis. Extract of Red Bone Marrow. (14) This is described as a glycerin extract of the red marrow of bones. It con- tains about 2% of proteids, about 1% of lecithin, and about 85% of glycerin. It is a brownish liquid of an agreeable aromatic taste. It is recommended for simple and pernicious anemia. Extract of Suprarenal Capsule. This is in brown, light particles which form a turbid solution with water. It is used chiefly externally in eye and nose operations, previous to cocaine, in con- junctivitis and other eye diseases, hay fever, capillary hemorrhages, etc. It is applied in 6 to 30% solutions. It is also used intravenously in 1% solution, 1 to 2 fluidrams being injected 2 to 3 times daily if necessary. Solutions should be prepared fresh each time with freshly sterilized water. Fagacid. This is a resin-like substance obtained from beech tar. It is a black, glistening mass of tarry odor and taste, fairly sol- uble in absolute alcohol and in solutions of caustic alkalies and alkaline carbon- ates, but insoluble in water and weak acids. It is recommended as an internal antiseptic and for the preparation of soaps, plasters, dressings, etc. Fayard's Paper. See Papier Fayard. Eebrile-Laxative Tablets. (131) These are made to contain in each tablet Quinine sulfate gr. I Acetanilid gr. 2 Tr. gelsemium m. 1 Aloin gr. 1/20 Podophyllin gr. 1/40 Capsicum gr. 1/4 The Febril-Laxative No. 2 contain salamid instead of acetanilid. Febrisol. "(194) Each 5 grains is stated to represent Phenacetine gr. 2 Acetanilid gr. ij4 Salol gr. y 2 Cit. caffeine gr. Yz Tartaric acid, Sodium bicarbonate, each .. sufficient This is also put in 5-grain tablets, plain and with quinine. Febrisol Liquid. Each fluidram is stated to contain Phenacetine gr. 2 Acetanilid gr. l l A PROPRIETARY AND SYNTHETIC REMEDIES. 739 Salol ..gr y 2 Cit. caffeine gr. Y± Tartaric acid, Sodium bicarbonate, each .. sufficient Fehr's Compound Talcum Powder. According to the patent specifications, this is a mixture of 2,000 parts of mag- nesium silicate (talcum) and 1 of car- bolic acid, to which y 2 part of zinc oxid may be added. Fellows' Compound Syrup of Hypo- phosphites. The manufacturers state that it con- tains potash, lime, iron, manganese, qui- nine, strychnine and phosphorus, the whole combined in the form of a syrup with a slightly alkaline reaction. Feralboid. (12) This is described as a "peptonized al- buminate of iron." It is put up in tab- lets, also in combination with quinine, with quinine and strychnine, and with manganese. Fercao. This is a dietetic preparation which is stated to consist of iron saccharate and cacao. Fermang. (Liq. Ferro et Mangano Peptonatus.) (116) This is described as a combination of peptonized albumen, iron and man- ganese. Fernine Tablets. These are stated to be composed of the active principles of the following drugs, so proportioned that each tablet contains Polypodium vulgare (female fern) gr. 2 Viburnum prunifolium gr. i/io> Helonias dioica gr. J /\ Monotropa uniflora , (nest root) gr V 2 Senecin gr. Caulophyllin gr. £ They are recommended as uterine tonics. Ferrated Gelsemium Compound. (Alterative Tonic.) (192) Each fluidram is stated to contain gelsemium, 2 grains ; arsenous acid, 47 1/48 grain; perchlorid of iron, % grain, combined with calisaya and aromatics. Ferratin. This is an acid albumin with 7% iron. It is a reddish-brown, odorless, tasteless powder, which is soluble in diluted alkalies, insoluble in water or diluted acids. It is claimed to be identi- cal with the form of iron as found in the liver. It is used as a hematinic in anemia, chlorosis, etc. Dose : 4 to 8 grains 3 times per day in wafers or with milk, children half as much. It is incompatible with acids. Ferratogen. This is an iron nucleinate obtained by growing yeast in a ferruginous med- ium. It is a yellowish-gray powder, in- soluble in water and in acids of the strength of the gastric juice, and for this reason does not produce any gas- tric disturbance. It is used in chlorosis and anemia in doses of 5 grains 3 times daily. Ferratose. This is described as a soluble form of ferratin, containing 3/10% of iron. Ferrichthol. (Ferric Ichthyol — Iron Sulfichthyolate.) This is an iron combination of ichthyol containing about 2^2% of iron. It is a brown-black, voluminous, non-hydro- scopic powder, nearly odorless and tasteless. It is insoluble in the ordinary solvents as well as in diluted acids and alkalies. It is said to be alterative, an- tiseptic, hematinic and tonic, and is rec- ommended in anemia, chlorosis, etc. The dose is 15 to 30 grains. Ferrinoids. (63) This is described as a "neutral solu- tion of the peptonized albuminates of iron and manganese, reinforced with bone marrow." A light brown liquid of palatable taste. It is also put r.p in an ars'eniatcd fcrm, each dessert- spoonful of v.'. ich cent; each of arsenous acid an .ins 1/60 grain ,1 strychnia. Ill THE STANDARD FORMULARY Ferrinol. (159) This is a compound of iron with nu- cleinic acid, containing about 6% of inm. It is a brown powder, soluble in warm water, from which solutions it is not precipitated by the ordinary iron reagents. It is recommended as a hematinic in anemia, chlorosis, etc. Ferripyrine. This is the same as Ferropyrine, which see. Ferroid. (74) This is described as a "solution of the citrate of the protoxide of iron in a simple elixir." Ferrocolin. This is the name given to a pepton- ized guaracol-iron-albuminate mixed with thymol in syrup. It is recom- mended for scrofula, incipient tubercu- losis, bronchial catarrh, etc. Ferroi. (71) This is stated to be an emulsion of cod liver oil containing 50% of the latter, each fiuidounce containing also 6 grains of iron phosphate. Ferroleum. (197) This is the formula as given by the manufacturers : Olei morrhuae (opt.) ^vii Ferri phosphat 3ii Phosphori gr. i Glycerini, etc., q. s. ad ^xv Ferro-Mangan Dieterich. (Liquor Ferro-Mangani Peptonati "Diet- erich.") This is a solution of a compound of peptone with iron and manganese, con- taining 0.6% of iron, 0.1% of manga- nese, and l.S% of peptone. It is pre- pared by covering 40 g. of iron and man- ganese peptonate "Dieterich" with dis- tilled water for one hour, then heating to boiling with 550 cc. of distilled water and allowing to cool. To this is now added 100 cc. of cognac, 75 cc. of 90% alcohol, 0.25 g. of saccharin, 12.5 cc. of aromatic tincture and distilled water to make 1000 cc. It is a clear liquid of a dark brown color and pleasant odor and taste; it is slightly acid in reaction. It is recom- mended as a reconstructive tonic and hematinic in anemia, chlorosis, convales- cence and whenever a general tonic is required. The dose is 1 to 4 fluidrams 3 times a day. Ferro-Manganese Peptonate. (182a.) Each fiuidounce is stated to represent 1% grains of metallic iron and 24 grain of metallic manganese in the form of neutral peptonized albuminates. It is recommended for anemia, chlorosis, gen- eral debility, and convalescence from wasting diseases. It is also put up 'with arsenic, each fiuidounce containing 1/30 grain of ar- senous acid, and with cascara, each fluid- ounce containing 60 grains of cascara. Ferropyrine. (Ferripyrine — Antipy- rineferric Chlorid.) (109) This is a compound containing about 64% of antipyrine and . 36% of ferric chlorid. It is prepared by mixing solu- tions of 1 part of crystallized ferric chlorid in 2 parts of 96% alcohol and 1 part of antipyrine in 2 parts of alcohol and 10 parts of ether, washing the pre- cipitate with ether and drying it on por- ous tiles at 40 C. It is a yellowish-red, crystalline powder, having an acid-as- tringent taste. It is soluble in 5 parts of cold water, but requires 9 parts of hot water for solution; it is soluble in alcohol but insoluble in ether. It forms a clear blood-red solution in water. It is incompatible with alkalies, their car- bonates and bicarbonates. It is stated to be a hematinic, hemos- tatic, astringent, analgesic and tonic. The dose is 5 to 15 grains in powder or so- lution. It is also used in a 1 to i l A% solution as an injection up to 20% solu- tion for hemorrhages. Ferro-Salicylate. This is stated to contain in each fluid- dram, 5 grains of true salicylic acid from oil of wintergreen, and 5 minims of tincture of citro-chlorid of iron in alkaline combination, with a menstruum of glycerin and simple elixir. Elsewhere PROPRIETARY AND SYNTHETIC REMEDIES. 741 it is stated to contain ammonium citrate and to have the odor of wintergreen oil. It is recommended for 'rheumatic affec- tions where a tonic is also needed. Ferro-Somatose. (Iron Somatose — Iron Albumose.) This is a light brown, almost tasteless and odorless, dissolving easily in water and aqueous liquids. It contains 2% of iron in organic combination. It is used as a dietetic and tonic in anemia, chlor- osis, convalescence, etc. There is also a Liquid Ferro-Somatose. The objection to ferro-somatose is that although freely- soluble, its solution requires some time. The liquid is said to be very palatable and contains no alcohol or other preser- vative agent. Ferrostyptin. This is a combination of hexamethyl- enetetramine hydrochlorid and ferric chlorid. It is a yellow crystalline pow- der, "easily soluble in water, insoluble in alcohol, ether and chloroform. It is a styptic, like ferric chlorid. It contains 15% of iron. It is used on gauze or cotton. Ferrum Sanguinis. (204) This is described as a semi-crystalline powder which forms a clear red solu- tion in water and consists of the color- ing matter or hemoglobin of blood. It is marketed in capsules each containing 4 grains. Fersan. This is a compound of iron and phos- phorus, prepared from the red corpus- cles of beef, which are split up into two bodies, one of which is used in this preparation and which has in it all the iron and phosphorus — containing albu- minoids of the blood. It is a chocolate- colored powder, of a slightly salty taste, and is soluble in water. It passes .through the stomach unaltered, but is completely absorbed by the intestines. Festoform. This is a solid formaldehyde which is obtained by mixing 3 parts of a 40% so- lution of formaldehyde with 1 part of soda soap, or by passing formaldehyde gas into a solution of soap. It forms a white mass, dissolving in water to make a feebly opalescent neutral liquid which is used for disinfection. It is marketed in tablet or pastille form. Fetrone. This is a new ointment vehicle devised by Liebreich. It is a solution of 3% of stearic anilid in yellow petrolatum, stearic anilid being a white crystalline substance made by heating aniline with stearic acid. The mixture is yellowish and inodorous, does not become rancid and 'at a temperature of 68° C. is capable of absorbing large quantities of water; it may be mixed with a great variety of medicaments without influencing their action or exerting any of its own. Fibrolysin. (130) This is a sterilized solution of the double salt of thiosinamine and sodium salicylate, containing 15%. of the double salt. It is prepared by mixing the two compounds in aqueous solution. It is an odorless liquid which does not keep when exposed to the air, and hence is marketed in sealed, amber glass vials, each containing 37 minims of the solu- tion (equivalent to 3 grains of thiosina- mine). The properties and uses are the same as those of thiosinamine with the advantage of quicker absorption and freedom from pain or irritation, on ac- count of its solubility and aqueous vehi- cle. The contents of one vial is used by subcutaneous, intromuscular, or intra- venous injection once a day or every 2 or 3 days. Fikulax. This is the formula as given in the Journal of the American Medical Asso- ciation : Pimento gr. V/z Oleum cassias drop *4 Ext. cascarae sag gr. 1/16 Magnesia gravis gr. 9 Sulf uris gr. 2 Rhamnus frangula gr. 1/12 Ext. sennae fluidum. m. 10 Zingiberis gr. 4 Cinnamomum gr. 4 742 THE STANDARD FORMULARY Cardamomum gr. 4 Myristica gr. 4 Ext. glycyrrhizae, q. s. Ficus celestia et chocolate, q. s. Filmaron Oil. This is a 10% solution of filmaron, the active principle of male fern, in castor oil. It is used for the removal of tape- worms. Filmogen. (Acetone Collodion — Col- losin.) This is pyroxylin dissolved in acetone with castor oil. It is used as a protec- tive as well as vehicle for remedies to be applied to the skin. Firolyptol. (194) This is stated to be composed of Eucalyptol m. x Cottonseed oil, purified oz. ss Firwein q.s.oz. i There is also a Firolyptol with Creo- sote which contains in addition to the above 10 m. of creosote (Morson's). Firolyptol with Hypophosphites contains 5 grains of calcium hypophosphites and 2 grains each of sodium and potassium hypophosphite. Firwein. (194) This is described as a balsam of fir wine with iodin, bromin and phosphorus. Each fluidram is stated to contain phos- phorus, i/ico grain, iodin, y 6 grain, and bromin, V 6 grain. Fitch's Kidney and Liver Cooler. This was found to be a solution of 56 grains of potassium nitrate to the ounce of water. — Analysis in British Med. Journ. Fitchmul. (Emul. Terebinthina Can- adensis Comp.) (72) This is stated to combine the active principles of fir balsam, venice turpen- tine, chloric ether, and a minute quantity of dilute hydrocyanic acid, tartar emetic and aromatics. Flag^'s Relief. Oil of clove, about fl.oz. 2 Oil of sassafras, about fl.oz. 4 Spirit of camphor, about. .. .fl.oz. 3 —J. J. Pierson, from N. I. Flavorone. (159) This is a culture of selected and test- ed lactic acid germs which is used for the purpose of ripening cream for butter making and as a ferment in the manu- facture of cheese. It is put up in the form of a powder contained in gelatin capsules. Flanders' Diffusible Tonic. Cinchonine sulfate parts 4 Extract of golden seal part 1 Alcohol parts 50 Water parts 145 —A. B. Stevens (from N. I.) Flint's Saline and Chalybeate Tonic. These are pills or tablets made accord- ing to Dr. Austin Flint's formula, each pill or tablet containing Sodium chlorid gr. ; Sodium carbonate gr. Potassium chlorid gr. Potassium sulfate gr. Potassium carbonate gr. Calcium phosphate gr. Calcium carbonate gr. Magnesium carbonate gr. Reduced iron gr. Mass of iron carbonate gr. Flon's Lenitive Syrup. Morphine hydrochlorid gr. Cherry-laurel water fl.dr, Tincture of cochineal ..fl.dr. 3 Simple syrup, to make fl.oz. 16 — H. Flora China. (Tasteless Quinine.) This was found to be upon examina- tion crystallized calcium sulfate. Floricin. This is a name applied to an oil ob- tained from castor oil by a special proc- ess. In contrast with castor oil it sa- ponifies readily with dilute solutions of alkali carbonates. The soaps so pre- pred are adapted for the purpose of rendering certain substances more solu- ble in water, such as for instance, vola- tile oils, phenols, resins, etc. The oil it- self is a yellowish brown, fluorescent liquid, viscous like castor oil. It mixes freely with petroleum oil and gasoline, is compeltely insoluble in alcohol and acetic acid, and a large proportion of water may be mixed with it. It has va- 3/5 3/20 1/10 1/20 1/2 1/20 1/20 9/20 1/20 18 1 PROPRIETARY AND SYNTHETIC REMEDIES. 743 rious uses in the arts and it also serves as an ointment vehicle. On account of the similarity of the name to phloridzin, the pure oil has been named dericin. Fluid Hydrastis. (131) This preparation is stated to represent the active medicinal constituents of the drug, . freed from associated resinous principles. It is non-alcoholic and non- resinous, and mixes with alcohol, glyc- erin, wine, syrup, or water without pre- cipitation. Fluid Lightning. See Cram's Fluid Lightning. Fluoroform Water. Fluorof ormol. . Fluoryl. This is an aqueous solution of fluoro- form, C H F 3 (containing 2.8%) ; it is said to be virtually odorless, tasteless, non-toxic and non-irritant. It is used in phthisis, tubercular infiltrations, and in local tubercular lesions of the glands, joints or skin (lupus). The dose is a tablespoonful 4 times daily. Fluorol. This is sodium fluorid which has powerful antiseptic properties. It is sol- uble in water, and does not coagulate albumen. Fluorrheumin. (Antirheumatin.) This is an ointment composed of 1% of fluorphenetol, 4% of difluordiphenyl, 10% of petrolatum, and 85% of lanolin. It is applied externally in acute articu- lar rheumatism, lumbago, sciatica, and similar affections. Formacoll. (220) A combination of formaldehyde with gelatin, said to be made according to the formula of Dr. Schleich. It is described as a non-irritant, non-poisonous anti- septic, free from odor. It is recom- mended for the treatment of purulent ulcers, suffurating wounds and fresh sutures. Formalbumin. (Formaldehyde - Ca- sein.) This is a yellowish powder, almost odorless and tasteless. It is insoluble in water. A protective wound antiseptic, forming a film from which the formal- dehyde is gradually liberated, thus con- tinually disinfecting the surface of the wound. Formaldehyde. This is solution containing about 40% of formaldehyde gas, which is prepared by the reduction of methyl alcohol. The U. S. P. preparation is called "solution of formaldehyde" and contains 37% of the gas. Commercial preparations are known by the names "formalin," "for- mol," etc. It is an almost ideal disin- fectant and deodorant. It is extensively used as a preserving and hardening agent for histological purposes, as an antiseptic in surgery and in all other branches of medicine, particularly in contagious diseases. It is valuable for rendering sweating feet, axillae, etc., in- odorous. It is frequently added to mix- tures, pastes, solutions, etc., for pur- poses of preservation. Formalin. Formol. See Formaldehyde. Formalin-Gelatin. See Glutol. Formamine. (117) This is the same as hexamethylena- mine, which see. Formamine Compound Tablets. Each tablet is stated to contain for- mamine, 2 grains, sodium salicylate, 5 grains, and colchicine, 1/200 grain Formamint. This is a combination of formalde- hyde and lactose and appears as tablets and powder. Formane. This is a combination of menthol, 8 drams, formaldehyde, 5 drams, and oil of rose geranium, 40 drops. It is used by inhalation for cold in the head. 7-H THE STANDARD FORMULARY Formasal. (Methylene Disallcylic Acid.) (116) This is a patented product prepared by the condensation of formaldehyde and salicylic acid. It is a tasteless, cream-white powder, insoluble in water, sparingly soluble in chloroform, and very soluble in ether and alcohol. It is marketed also in the form of compounds with various bases, such as with potassium (called Kaliformasal), calcium (Cal formasal), bismuth (Bis- formasal), etc. The alkali salts are rec- ommended in cases of uric acid dia- thesis in doses of 5 to 15 grains, while the alkaline earth salts are recommended in gastro-intestinal disturbances. Formaseptol. (117) This is a liquid antiseptic stated to contain J<£% of formaldehyde in com- bination with cinnamol, thymol, eucalyp- tol. menthol, gaultheria, sodium borate, and benzoic acid. Formatone. (Solution of Pentafor- mates.) (221) This is stated not to contain any su- gar. Each fluidounce contains Sodium formate gr. 16 Strontium formate gr. 14 Magnesium formate gr. 8 Lithium formate gr. 2 Quinine formate gr. 2 Formenthol. This is stated to be an alkaline solu- tion containing thymol, eucalyptol, for- maldehyde, "benzo-boric" acid, and red gum. Formetto Capsules. (117) Each capsule is stated to contain 2 grains of hexamethylenamine, 6 min- ims of oleoresin of saw palmetto, 2 minims of oil of sandalwood, and ^4 minim each of oils of cinnamon and nutmeg. Formicine. (Formaldehyde Aceta- mide.) This is a very hygroscopic substance and hence is marketed only as a concen- trated solution which is a thick, syrupy liqr.id of a yellowish color, miscible in all proportions with water, alcohol, or chloroform, readily soluble in glycerin, decomposed readily by acids and alka- lies, slowly by water, formaldehyde be- ing liberated. It is used as a disinfect- ant and deodorant for abscesses, cystitis, purulent wounds ; 2% solution is used for injection into the bladder and 5% for abscess cavities. Formidine. (159) This is a compound of iodin, formal- dehyde and salicylic acid. It is a red- dish-yellow powder containing 47% of iodin. It is insoluble in water, acids or alcohol, but readily soluble in alkaline solution. It is 'perfectly stable in the dry state. It is used as a substitute for iodoform, both internally and external- ly. On contact with alkaline organic se- cretions it is slowly dissolved and de- composed into its three original com- ponents. The dose internally is 1 to 5 grains. Formin. (130) This is the same as hexamethylena- mine, which see. Do not confound with formine. Formine. (77) This is described as a purified 40% solution of formaldehyde. Do not con- found with formin. Formochlorol, Solidified. (77) This is a mixture of polymerized for- maldehyde (70%) and neutral salts (30%) — kind not stated — which pro- duces formaldehyde when heated in the autoclave. Formolid. (Warn/pole's Antiseptic So- lution. (211) Each fluidounce is stated to contain Acetanilid gr. 2 Boric acid 2% Boroglyceride 1% Sodium benzoate ^2% Formaldehyde sol Ya % Alcohol . ' 15% Eucalyptol. menthol, thymol, and oil of wintergreen. PROPRIETARY AND SYNTHETIC REMEDIES. 74/ Fortoine. (Methylene-Dicotoin.) (222) This is a condensation product of co- toin and formaldehyde. It forms yel- low, needle-shaped, tasteless crystals, insoluble in water, sparingly soluble in alcohol, ether or benzol, but freely sol- uble in dilute alkalies, acetone or chloro- form. It has an antiputrefactive, bac- tericidal action, and is recommended as an astringent antiseptic in acute and chronic intestinal catarrh and in the protracted diarrheas of consumptives. Fosgate's Anodyne Cordial. According to a communication to the Ch. & Dr., this was first put up as a substitute for Godfrey's Cordial. As originally prepared it was understood to be composed of rhubarb, soda, lauda- num and cinnamon. To these were sub- sequently added, it was said, camphor and capsicum. x N. I. offers the following as a similar preparation : Fluid extract of rhubarb. .. .fl. dr. 5 Fluid extract of rhatany. . . .fl.dr. 2 Fluid extract of ginger drops 6 Paregoric fl.dr. 1 Simple syrup fl.dr. 1 Diluted alcohol fl.dr. 5 Fossilin. A petroleum product similar to petro- latum. — Coblentz. Fournier's Wine of Creosote. Creosote g. 5 Alcohol g. 100 Simple syrup g. 350 Malaga wine g. 400 — H. Franck's Grains de Sante. According to Guibourt, these consist of aloes and licorice extract, according to Hager's analysis, of 1 part of gum gamboge and 4 parts of aloes. Freligh's Remedy. (219) Twenty minims of this preparation are stated to contain the equivalents of Tinct. hyoscyamus nig m. 3 Tinct. colchicum sem m. 1 Tinct. bryonia m. 1 Tinct. aconite m. 1 Magendie's sol. morph m. 2 Iodide potass gr. ^ and "fractional parts" of apocynum cann., cimicifuga rac, cannabis ind., rhus tox., belladonna, matricaria, gaul- theria, and cactus grand. It is recommended for rheumatism, neuralgia, gout and gravel. Freligh's Tonic. (Phosphorized Cere- bro-Spinant.) Ten minims are stated to contain the equivalents of Tinct. mix strychnos m. 1 Tinct. ignatia amara m. 1 Tinct. matricaria m. 1 Tinct. cinchona m. 4 Tinct. gentian m. Yi Tinct. Colombo m. ^2 Tinct. phosphorus gr. 1/200 Aromatics m. 2 Frey's Vermifuge. According to a communication to D. C, this is composed of Castor oil fl.oz. 1 Aromatic syr. rhubarb fl.oz. 1 Oil of wormseed drops 30 Croton oil drops 5 According to the manufacturers, it contains castor oil, oil of wormseed, rhubarb root, senna leaves, cinnamon bark, clove, nutmeg, cardamom and sugar. Fringe Tree Alterative. (143) This is stated to contain fringe tree bark, wahoo bark, echinacea root, bur- dock root, senna leaves, and sodium phosphate. Fruneau's Antiasthmatic Paper. According to Hager, this is the same as "paper of potassium nitrate." Furunculin. This is the name for a preparation derived from brewer's yeast, and rec- ommended in furunculosis, catarrh of the stomach and intestines, etc. The dose is 10 to 30 grains 3 times daily be- fore meals, with milk or beer. Gadberry's Mixture. This is the Splenetic Mixture of the National Formulary. Gaduol. (Alcoholic Extract of Cod- Liver Oil.) A brownish-yellow, oily liquid of a bitter, acrid taste derived bv alcoholic •k; THE STANDARD FORMULARY extraction of cod-liver oil. It is said to contain traces of iodin, bromin and phosphorus. One part is stated to rep- resent 12 parts of cod-liver oil. It is used for the same purposes as the oil. The dose is 5 to 15 minims in capsules, wine or elixir. Gaiacophosphal. (Guaiacol Phos- phate.) This- is stated to contain 92.2% of guaiacol. It is a white powder, of pun- gent taste, sparingly soluble in water, more soluble in alcohol, glycerin, chlor- oform and oils. It is used as an antitu- bercular in doses of 3 to 15 grains 3 times a day. Gallanol. (Gallic Acid Anilide — Gal- linol.) This is in gray, bitter crystals or pow- der. It is slightly soluble in cold water, readily in boiling water and in alcohol and ether, insoluble in chloroform or benzine. It is used as an antiseptic in- stead of pyrogallic or chrysophanic acid for dermal purposes, as in psoriasis, eczema, etc. Application : 5 to 10 to 25% powder, solution or ointment. Gallicin. (Methyl Gallate.) This is in white, fleecy needles, which are soluble in hot water and alcohol, also in ether. It is a reducing agent and anti-catarrhal. It is used in powder form, chiefly in conjunctival catarrh. Gallobromol. (Dibromogallic Acid.) This is in small, gray crystals, which are freely soluble in alcohol, ether and boiling water, and soluble in 10 parts of cold water. It is a sedative, like potas- sium bromid, and an antiseptic astrin- gent, useful in gonorrhea and cystitis. Dose : Same as of potassium bromid. In gonorrhea and cystitis, it is used in 1 or 2% solution. Gallogen. (Ellagic or Benzoaric Acid.) This is the astringent principle of divi-divi. the pods of Caesalpina coriari. It is a yellowish, odorless, tasteless pow- der, insoluble in all acid and neutral li- quids, but soluble in alkaline liquids to the amount of 2%, such solutions, how- ever, being very readily oxidized. Its solutions in alkaline media give all the reactions of tannic aqd with iron salts, gelatin solution, etc. It is incompatible with alkaline liquids. It is an astringent and antidiarrheic, and is slowly decom- posed in the intestinal tract, thus exert- ing its astringent action gradually dur- ing its passage. It has been recom- mended in dysentery, cholera infantum, diarrhea, and is said to be useful even in those of syphilitic or tuberculous ori- gin. The dose is 5 to 8 grains for chil- dren, 10 to 15 grains for adults, sus- pended in neutral or slightly acid media. Garantose. This is the same as saccharin, which see. Gardner's Syrup of Hydrodic Acid. (78) This is stated to contain 1.28% of ab- solute hydriodic acid (hydrogen iodid) or 6.66 grains of pure iodin in each fluidounce. Gardner's Syrup of Hypophosphite of Ammonium. Each fluidounce is stated to contain 16 grains of ammonium hypophosphite. Gare's Lecithine. This is defined as "true organic phos- phorus (glycerophosphate of cholin)," also as "a definite chemical extracted from the yolks of fresh eggs and repre- senting the molecule which contains the phosphorus in the exact form in which it exists in the human organism." It is marketed in the dry, granular form and as a glycerole. The dose of the form is 3 to 5 grains, to be administered in capsules, of the latter J / 2 to 1 teaspoon- ful, 3 times a day. Gasterin. This is a name applied to the gastric juice of dogs. Gasterine. This is a name applied in France to bismuth phosphate. PROPRIETARY AND SYNTHETIC REMEDIES. 74? Gaultherine (formerly called Asep- sin.) (131) This is the sodium salt of methyl sali- cylate prepared from natural oil of win- tergreen. It is a pinkish powder, slowly soluble in cold water, more readily solu- ble in hot water, very soluble in alcohol, insoluble in ether and chloroform. It is an antiseptic and anti fermentative and is used internally and externally. Gaulsalol Capsules. (38) Each capsule is stated to contain 5 grains of salol and 5 minims of methyl salicylate. Gelanthum. This is a mixture of 2^2% each of gelatin and tragacanth, 5% of glycerin, 2% of thymol as a preservative, and water. It is lauded by Unna as an ideal water-soluble vehicle for the appli- cation of medicines for skin medication. It forms a smooth, homogeneous cover- ing without a tendency to stickiness. It takes up 50% of ichthyol, 40% of sali- cylic, acid, resorcin or pyrogallol, 5% of carbolic acid, and 1% of mercuric chlorid. Gelasepsin. This is a 1 to 2% sterilized solution of gelatin in physiological salt solution. Gelatol. An ointment vehicle consisting of a mixture of oil, glycerin, gelatin and wa- ter.— Helbing's Mat. Med. Gelatose-Silver. This is Albargin, which see. Gelin's Granules of Arseniate of Gold. These are the same as Addison's Gran- ules of Arseniate of Gold, which see. Gelis & Conte's Dragees of Lactate of Iron. According to Hager, these contain each 5 centigrams of lactate of iron. Gelone. This is a plaster consisting of two layers, an outer insoluble covering com- posed of a tough, elastic agar mass, and a layer of adhesive mixture soluble in water. The latter is a gelatinous sub- stance of great adhesive power, it ab- sorbs water readily, and is suitable to serve as a base for mixtures of various medicinal agents (zinc oxid, salicylic acid, ichthyol, chrysarobin, mercury, gal- lacetophenone, etc.) The plaster is ap- plied by moistening the adhesive surface and pressing gently upon the skin, and is removed with a minimum of irrita- tion to the affected parts by gently sponging the outer layer with water, which causes the tough covering to sepa- rate, after which the soluble adhesive mixture may be washed off. Gelseminine. This is an alkaloid derived from gel- semium. It is in very small white cry- stals which are soluble in alcohol and ether. The hydrochlorid and sulfate are used also, both of which are soluble in water. It is used in rheumatism, neuralgia, and dysmenorrhea, also used as an anti- dote to strychnine. The dose is 1/125 to l /$° grain, the maximum single dose being 1/30 grain, the maximum daily dose 1/5 grain. Genitone. (Elixir Viburnum Pruni- f olium Compound — Utero-Tonic Cordial.) (131) Each fluidounce is stated to contain 2 grains of Pulsatilla, 4 grains of passi- flora, 5 grains each of golden seal and life root, 8 grains of black haw, and aromatics. It is recommended for the functional derangements peculiar to women. Geoline. (142) This is described as liquid petrolatum, U. S. P. George's Pectoral Paste. Dissolve 5 av. ounces of gum arabic and 3^ av. ounces of sugar in 8 fluid- ounces of water by the aid of a water bath, then add 50 grains of calcined mag- nesia and 1 grain of morphine hydro- chlorid, and enough decoction of licorice root (1 in 4) to make a suitable mass, and divide this into small, rectangular lozenges or into pastilles. — H. 74:8 THE STANDARD FORMULARY Geosote. (Guaiacol Valerianate.) This is a yellow, oily liquid which has the characteristic odor of valerianic acid, and is insoluble in water, soluble in alcohol and ether. It is said to be useful in chlorosis and tuberculosis and as an intestinal antiseptic in doses of 3 to 10 grains 3 times a day. Gerdal. This is a nutritive compound of beef juice, albumen and sugar. It is a gray- ish-yellow powder, of pleasant odor and taste which is given in doses of three teaspoonfuls 3 times daily, either alone or mixed with other food. German Cathartic Salt. This article is stated to be prepared exactly according to the formula in the German Pharmacopeia for Sal Therma- rum Carolinensis. Germicidal Discs. (McClintock.) (159) Each disc is stated to contain 3/8 grain of mercuric iodid and 16 grains of sodium bicarbonate. Germicidal Soap. (McClintock.) (159) It is a bluish-white powder compress- ed into cakes, containing 2% of mer- curic iodid in combination with hard soap. It is claimed to be a disinfectant which does not coagulate albumin nor corrode steel or nickel. It is recom- mended for the disinfection of the hands and for washing out infected cav- ities. There is also a "germicidal soap, mild," and a "germicidal soap, soft," which contain but 1% of mercuric iodid. Giles' Iodide of Ammonia Liniment. Alcohol fl.oz. 8 Iodin gr. 15 Camphor dr. 2 Oil of lavender fl.dr. 1 Oil of rosemary fl.dr. 1 Water of ammonia fl.oz. 1 — Kilner. This corresponds almost exactly to the liniment of ammonium iodid of the N. F. Gilt Edge Butter Compound. This contains 30% of pepsin and 70% of hydrous sodium sulfate, besides a trace of pink coloring matter. — Wiley. Girard Laxative Pills. (81) These are silver-coated, ovoid pills, each containing Leptandrin gr. 1/8 Cascarin gr. 1/8 Podophyllin gr. 1/16 Ext. belladonna leaves gr. 1/16 Strych. sulf gr. 1/160 Aromatics and carminatives, q. s. Girard Uterine Tonic. (Pil. Caulo- phyllen Comp.) Stated to contain caulophyllin, scutel- larin, and cypripedin. Glacialin. This is an English patented article consiting of boric acid, 18 parts, borax, 9 parts, sugar, 6 parts, glycerin, 9 parts, and water, 400 parts. Glidin. (Dr. Klopfer's Wheat Albu- min.) This contains 96% of albumin and 1% each of salts and lecithin. It forms a fine yellowish, inodorous, tasteless pow- der that swells up with water and aque- our liquids. It contains no nucleins and the production of uric acid in the system is thus lessened. It is recommended for the baking of bread intended for suf- ferers from diabetes and kindey dis- eases. Glonoin. This is another name for nitroglyce- rin, spirit of glonoin therefore being spirit of nitroglycerin, U. S. P. or i%» Gluside. This is a synonym for Saccharin, which see. Glutannol. This is a compound of vegetable fibrin and tannin, which is insoluble in water or slightly acid liquids, and is therefore not dissolved in the stomach but is dis- solved by the intestinal fluids. It is em- ployed as an intestinal astringent in doses of 8 to 15 grains for adults and 4 . PROPRIETARY AND SYNTHETIC REMEDIES. 749 to 8 grains for children, either in the form of powder or suspended in mix- tures. Gluten Suppositories. These consist of cocoa butter contain- ing 10% of wheat flour. — Vulpius, in Ph. Centralh. Glutiform. A combination of formaldehyde with gelatin. Glutol. (Dr. Schleich.) (Formalin- Gelatin.) (178) This is a chemical combination of gelatin and formaldehyde. It is pre- pared by dissolving 20 g. of gelatin in 15 g. of water, adding 1 drop of formal- dehyde solution, exposing the mass so obtained, in a covered box over lime, to the vapor of formaldehyde by the aid of a layer of cotton wool saturated with it until a dry mass is produced, and re- ducing this to powder. It is a white, odorless powder, insoluble in water un- der ordinary conditions, but it is dis- solved when heated with water under pressure, the solution thus produced gelatinizing on cooling. It is not chang- ed by acids, alkalies or saline com- pounds, but is slowly decomposed on contact with living tissue, formaldehyde being slowly liberated. It may be steril- ized without decomposition. It is claimed that while it is in itself non-antiseptic, non-irritant, and non- toxic, it becomes antiseptic and bacteri- cidal on contact with living cells, in con- sequence of the gradual elimination of formaldehyde. It is used in the undi- luted form as an antiseptic dusting pow- der and is applied to burns, scalds, ulc- ers, wounds, etc. Gluton. This is a form of glutose, made from gelatin, which does not gelatinize and is recommended as a nutriment in cases of obesity and diabetes. Glycerin Emollient. (159) This is stated to be a mixture of Tragacanth gr. 263 Boric acid dr. 6 Corn starch oz. 3 Glycerin oz. 28^2 Oil of wintergreen gr. 30 It is a soft and transparent solid, in- tended as a lubricant in gynecologic and surgical practice. It is put up in collap- sible tubes and is to be applied to the dry skin. After use it can be washed off with water. Glycerinum Pepticum. (70) This is a concentrated glycerin extract of the peptic juice of the stomach. Glycerite of Styrolene. (160) This is stated to contain styrolene, styracin, benzoic acid, cinnamic acid, acetanilid, wild cherry, and glycerin. It is recommended as an antispasmodic, expectorant and antiseptic. Glycerole of Celery Compound. This preparation is put up by several firms. As made by Sutliff & Co. and Baker & Co., each fluidram is stated to contain 3 grains each of celery and Ger- man chamomile and 5 grains of catnip. As made by Hazen Morse, each fluidram is stated to contain 4 grains of celery seed, 5 grains of catnip, 2 grains of chamomile, and enough anise to flavor. It is recommended as an anodyne and hypnotic, instead of opium, or when the latter cannot be used, as for teething in- fants. Glycerole Heroin Compound. (159) Each fluidounce is stated to contain Yz grain of heroin, 24 grains of ammonium hypophosphite, 8 grains of henbane, 28 grains of white pine bark, and tolu bal- sam, glycerin and aromatics, q. s. Glycerole of Lecithin. See Lecithin Glycerole and Gare's Lecithine. Glycerole of Lecithine, Gare's. See Gare's Lecithine. Glycerole Pepsin and Wafer Ash. (159) This is stated to contain 40 grains of saccharated pepsin and 30 grains of wafer ash to each fluidounce. 750 THE STANDARD FORMULARY Glycerole Yerbine Compound. (159) Each fluidounce is stated to represent Verba santa gr. 90 Licorice root gr. 90 Grindelia gr. 30 Wild cherry gr. 30 Potassium bromid gr. 7V2 Pine tar gr. 2)4 Salicylic acid gr. 2 It is a sedative expectorant. Glycerophosphates. These are the salts of glycerophos- phoric acid. The calcium compound has already been described (see Calcium Glycerophosphate). It is prepared by heating glycerin and phosphoric acid for a considerable time and then neutraliz- ing with lime. The precipitated calcium phosphate is removed while the calcium glycerophosphate remains in solution. From the calcium salt the other salts can be prepared by precipitating calcium by the appropriate salt of the metal whose glycerophosphate is desired. Po- tassium and sodium glycerophosphates are in the form of dense, syrupy liquids which are exceedingly soluble in water and representing 75% of the respective salts in a dry condition. Calcium, iron, lithium, magnesium, and manganese glycerophosphates are pulverulent salts, moderately soluble in water. The aque- ous solutions of glycerophosphates de- compose in a short time. They should be made with sterilized water, but hot liquids should not be used. These salts were introduced as "nerve foods" and tonics on the theory that their phosphorus, being a step nearer lecithin, is assimilated more readily than the hypophosphites. The potassium and sodium salts may be given hypodermi- cally in doses of 3 to 4 grains in normal salt solution, or per mouth in doses of 4 to 10 grains in water or syrup. Cal- cium, iron, lithium, magnesium and man- ganese glycerophosphates are given in doses of 10 grains each; the quinine salt in doses of i l / 2 to 5 grains; and the strychnine salt in doses of 1/60 to 1/20 grain. 8 1/2 1/16 Glycerophosphates Comp. (221) Each fluidounce is stated to contain Sodium glycerophosphate. . .gr. 16 Calcium glycerophosphate, .gr. Iron glycerophosphate gr. Manganese glycerophos- phate gr. Quinine glycerophosphate ..gr. Strychnine glycerophos- phate gr. It is stated not to contain any sugar. Glycerophosphates Syrup. (116) This is stated to contain the glycero- phosphates of iron, manganese, quinine, strychnine, calcium, sodium, and potas- sium. Glycerophosphates Syrup and Tab- lets (Huxley) — (Ner-Vigor.) Each fluidram of the "syrup" (free from sugar) and each tablet represents 4 grains of glycerophosphates of lime, soda, potash, manganese and iron with 1/250 grain of strychnine. Glycerophosphoids. (89) These are soft capsules each said to contain Calcium glycerophosphates, .gr. 3 Gaduol m. 5 Creosote m. 2 Strychnine phosphate gr. 1/60 Glyco-Chlorides. (214) Each fluidram is stated to contain Mercury bichlorid gr. 1/80 Arsenic chlorid gr. 1/49 Tr. iron chlorid m. 4 Dil. hydrochloric acid m. 5 Glycerin. Glycogen. (204) This is a substance produced by the digestion of starch and exists in the liver of animals and in some low forms of plant life. It forms a yellowish- white powder, soluble in water. It has been recommended by French physicians in tuberculosis, diabetes, neurasthenia, etc. It is put up in i-grain capsules, 1 to 5 of which are to be given daily. Glycoline. (Mineral Glycerin.) This is a colorless and odorless liquid petrolatum, according to the manufac- turers' statement. •ROPRTETARY AND SYNTHETIC REMEDIES. 751 Glycomorrhum. This is a proprietary cod-liver oil sub- stitute which has been introduced into Paris hospitals. Tt consists principally of glycerophosphates and hypophosphites with some of the constituents of cod- liver oil. Glycones. (117) This is a name for glycerin supposi- tories, dlyconin. This is the glycerite of yolk of egg of the U. S. P. Glycosal. (Glycerin-Salicylate.) This forms a white powder readily soluble in alcohol, soluble in ioo parts of water. It is employed in place of sodium salicylate. Glyco-Thymoline. (Kress.) According to labels formerly used, each fluidounce was stated to contain (in grains?) sodium 24, boric acid 4, benzoin 4, salicylic acid 0.33, eucalyptol 0-33> "thymoline" 0.17, betula lenta 0.08, menthol 0.08, pinus pumilio 0.17, glyce- rin and solvents sufficient. Glycotine Comp. (63) Each two teaspoonfuls is stated to contain 4' grains of the combined glyce- rophosphates of lime, soda, iron and manganese, with 1/80 grain of strych- nine glycerophosphate. Glycotone Comp. Capsules. Each capsule is stated to represent two teaspoonfuls of Glycotone Comp., which see. Glyco-Vitse. (Glycerole of Glycero- phosphates Comp.) (154) The composition is stated to be 8 grains of sodium glycerophosphate and 4 grains of calcium glycerophosphate combined in a bland, neutral aromatized vehicle. Glykaolin. (Pasta Alumini Silicatis Comp.) (221) This is described as a compound of aluminum silicate, salol and glycerin, made into a smooth paste which is rec- ommended as a depletive in local con- gestion and inflammation. Picrated Glykaolin is the same with a small amount of picric acid and is espe- cially recommended for burns. Glymol. (7) This is claimed to be a liquid hydro- carbon obtained from petroleum, proba- bly therefore a purified liquid petrola- tum. Glyphocal. (185) This syrup stated to contain the glyc- erophosphates of calcium, sodium, po- tassium, magnesium and iron, with pep- sin and diastase. Godfrey's Cordial. This preparation is now recognized by the N. F. under the name Mixture of Sassafras and Opium. Gold Monobromid. (Aurous Bromid.) This is in yellowish-gray, friable masses, insoluble in water. It is used as an anti-epileptic and against migraine. The dose as an anti- epileptic is 1/10 to 1/5 grain 2 or 3 times daily in pills, as an anodyne, 1/20 gra'n twice daily. Gonosan. (172) This is a solution of the resins of kava kava in oil of sandalwood. It is a yellowish-green aromatic fluid which is put up in 5-grain capsules containing 1 grain of the former and 4 grains of the latter. It is used for gonorrhea. Good Samaritan Oil. This was patented in 1872, the com- position being Oil of origanum fl.oz. Oil of hemlock fl.oz. Oil of cedar fl.oz. Oil of sassafras fl.oz. Oil of wintergreen fl.oz. Oil of valerian fl.oz. 2 Olive oil fl.oz. 2 Tincture of myrrh fl.oz. 2 Tincture of capsicum fl.oz. 2 Ammonia water fl.oz. 2 Laudanum fl.oz. 1 Ether fl.oz. 1 Gum camphor oz. l / 2 Alcohol oz. 32 Gorite. (Calcium Peroxid.) This is a yellow powder, slightly solu- ble in water with the evolution of oxy- 752 THE STANDARD FORMULARY gen. It has been recommended as an antacid and disinfectant in acid dyspep- sia and summer diarrhea of children, in doses of 3 to 10 grains. It is also used in tooth powders. Goss' Improved Laxative Pills. Each pill contains Euonymin gr. l /i Podophyllin gr. Y$ Extract of henbane gr. J4 Comp. ext. colocynth gr. *4 Extract of butternut gr. H Ext. black Indian hemp gr. J^ Ext. cascara sagrada gr. Yz Goudrogenin. This is a dry preparation of pine tar which is in the form of brown scales which is readily soluble in water. The solution is said to possess all the prop- erties of tar water and to be strongly antiseptic. Gouraud's Oriental Cream. This is said by Tuttle and Snow to consist of calomel and water, about 39 grains of the former to 1 fluidounce of the latter, no perfume or glycerin being present. — N. I. The claim of the manufacturer is that the principal ingredients are epsom salt and table salt. Gouttine. This is another and later .name for citarin, which see. Grain's de Sante. See Franck's Grains de Sante. Graminin. This is a dry form of hay fever serum intended for use as a snuff in hay fever. Grapiol. (84) Described as 5-minim capsule contain- ing apiol, ergot and aloin, and recom- mended for various menstrual disorders. Gray's Specific Pills. Nearly all of these "specific" pills are composed (W. D.) of asafetida, with a little camphor and sometimes hops, or lupulin, e. g. : Asafetida gr 2 Camphor gr. 1 Lupulin gr. Y& The "specific action" is in the direc- tion of an anaphrodisiac. Green Mountain Kidney Cure. This is stated to contain Canada bal- sam (balsam of fir), fresh extract of sweet elder bark, fresh extract of spike- nard root, fresh extract of sumac, podo- phyllin and ipecacuanha. Green Mountain Oil. Oil of eucalyptus m. 10 Oil of spearmint m. 10 Oil of cassia m. 20 Oil of peppermint fl.oz. i l / 2 Oil of wintergreen fl.oz. 2 Oil of sassafras fl.oz. 3 Oil of sesame fl.oz. 16 Menthol gr. 30 Chlorophyll gr. 30 Mix all of the oils except the sesame and add the menthol. Dissolve the chlorophyll in 4 ounces of sesame oil by the aid of heat, mix the two solutions, and add the remainder of the oil of sesame. — Era, 1905. Green Mountain Salve. Resin av.lb. 5 Burgundy pitch av.oz. 4 Beeswax av.oz. 4 Mutton tallow av.oz. 4 Oil of hemlock fl.oz. 1 Balsam of fir fl.oz. 1 Oil of origanum fl.oz. 1 Oil of red cedar fl.oz. 1 Venice turpentine fl.oz. I Oil of wormwood fl.oz. Yz Verdigris, very finely pul- verized av.oz. 1 Melt the first three articles together and add the oils, having rubbed the verdigris up with a little of the oils and put in with the other articles, stirring well; then pour into cold water and work as wax until cool enough to roll. — A. D. Greenhow's Cholera Mixture. Guaiac av.oz. 1 Clove av.oz. 1 Cinnamon av.oz. 1 Brandy fl.oz. 29 Macerate the drugs in moderately fine powder with the brandy for 7 days, and filter. PROPRIETARY AND SYNTHETIC REMEDIES. 753 Griffith's Compound Mixture of Gua- iac, Stillingia, Etc. This is stated to contain guaiac, stil- lingia, prickly ash, turkey corn, colchi- cum, black cohosh, sarsaparilla, salicy- lates of the alkalies, potassium iodid, and other remedies. Grillon's Tamar Indien. See Tamar Indien. Grimault's Matico Injection. Made by dissolving 8 grains of copper sulfate in 16 fluidounces of infusion of matico, the latter being prepared from I ounce of leaves. — Wittstein's Analysis. Grimault's Paullinia Powders. According to Hager, these are put up in boxes of 12 powders, each weighing about 25 grains, containing powdered guarana with possibly some unroasted cocoa. Grimault's Syrup of Bark and Iron. This is similar to a solution of 10 grams each of iron and sodium pyro- phosphates in 500 grams of simple syrup to which 50 grams of tincture of red cinchona has been added. — Hager. Griserin. This consists of loretin combined with 4 r A% of sodium carbonate or 6}i% of sodium bicarbonate. It is advertised as being a non-toxic specific in tuberculosis, cancer, syphilis, etc. It is put up in powders or cachets, or in cachets with tannalbin. Guacamphol. (Guaiacol Camphorate.) This is a combination of guaiacol and camphor. It is in white odorless, taste- less needles, insoluble in water, moder- ately soluble in alcohol or chloroform. It is used to stop the night sweats and diarrheas of phthisical patients. The dose is 3 to 15 grains. Guaethol. (Pyrocatechinmonoethy- lether — Ethyl-Guaiacol — Ajacol- Thanatol.) This is an oily liquid, solidifying in the cold and forming crystals which be- gin to melt at about 26° C. It is the ethyl compound corresponding to guaia- col, which is the methyl compound. It is said to act more effectively than guaiacol. A single dose is 2 to 4 grains, the daily dose, 16 grains. It is also ap- plied externally. Guaiacetin. (Sodium Pyrocatechin- Monactetate.) This is a white, odorless powder, sol- uble in 30 parts of water. It is used as a substitute for guaiacol and creosote in tuberculosis. The dose is 8 grains. It is marketed in the form of powder and tablets. Guaiacol. (Methyl-Pyrocatechin.) This is a colorless crystalline solid melting at 83 C, or as an almost color- less, refractive liquid boiling at 205 C. The specific gravity of the liquid is 1.14. It is soluble in 53 parts of water, in all proportions of alcohol and ether, also soluble in acetic acid and in an equal part of glycerin. It is used internally as an antitubercular and externally as an analgesic. The average dose is 8 min- ims. Guaiacol Albuminate. See Histosan. Guaiacol Camphorate. See Guacamphol. Guaiacol Carbonate. See Duotal. Guaiacol Carbonate Comp. (141) This is put up in capsules, each one of which is stated to contain Guaiacol carbonate gr. 1^2 Calcium hypophosphite ....gr. J4 Ichthyol gr. l / 2 Strontium arsenite gr. 1/120 Olive oil, to make m. 5 It is recommended for incipient tu- berculosis, chronic pneumonia and allied affections. Guaiacol Cinnamate. See Styracol. Guaiacol Co. Elixir. See Triacol. '54 THE STANDARD FORMULARY Guaiacol-Ethylene. (Ethylene Ether of Guaiacol.) This is in colorless needles, which are sparingly soluble in water but are read- ily soluble in alcohol. It is an antitu- bercular, like guaiacol. Dose : 8 to 15 grains twice daily, in pill or cachet. Guaiacol Phosphite. (Guaiacol-Phos- phal.) See Gaiacophosphol. Guaiacol-Piperidin. See Guaiaperol. Guaiacol Salicylate. See Guaiacol-Salol. Guaiacol-Salol. (Guaiacol Salicylate.) This is the salicylic ester of guaiacol and is the analogue of salol as the sali- cylic ester of phenol. It is a white, crystalline, tasteless powder, of a salol- like odor. It is insoluble in water but soluble in alcohol, ether and chloroform. It is decomposed by alkalies and alkaline carbonates and strong acids. This com- pound acts like its constituents, being antiseptic and antirheumatic. It is rec- ommended in phthisical diarrhea, dysen- tery, rheumatism, etc., the dose being 15 grains. Guaiacol-Somatose. This is a somatose preparation con- taining 5% of calcium guaiacol-sulfo- nate. Guaiacol Valerianate or Valerate. See Geosote. Guaiacoline. This is stated by the manufacturers to be an emulsion containing the medicinal properties of cod-liver oil, guaiacol and alkaline phosphates, the formula being given as follows : Pure Norwegian oil drops 60 ( iuaiacol drops 2 Primus serotina, fl. ext.... drops 15 Alkaline phosphates gr. 2 Just what relation the above ingredi- ents bear to the total quantity of emul- sion, the manufacturers fail to state. Guaiacyl. (Calcium Guaiacol-Sulfo- nate.) This is a bluish gray or yellowish gray, odorless powder, of an astringent- sweetish taste. It is soluble in water and alcohol but not in fatty oils. It is used hypodermically as a local anesthetic in minor and dental surgery in the form of 5% aqueous solution, of which 8 to 24 minims are injected at one time. Guaiaform. (Diguaiacolmethylene.) This is a combination of guaiacol and formaldehyde. It is a yellowish, almost odorless and tasteless powder, is insolu- ble in water but soluble in alcohol and strong alkaline solutions. It is recom- mended for tuberculosis in the same doses as guaiacol. Guaialin. (116) This is described as the benzoic acid ester of methylene-diguaiacol, obtained by passing formic aldehyde gas through a mixed and heated solution of benzoic acid, guaiacol and phosphorus oxy- chlorid. It is a pea-green colored amor- phous powder, which is stated to con- tain over 60% of guaiacol, 30% of ben- zoin and about 7% of formic aldehyde. It possesses the antitubercular, antipy- retic and alterative tonic properties of guaiacol, plus the virtues of its other constituents. Guaiamar. (Guaiacolglycerylester.) (122) This is the monoguaiacol ester of glycerin. It is a white, crystalline, non- hygroscopic powder of a bitter and aro- matic taste. It is soluble in 20 parts of cold water but very soluble in warm water. It is soluble in alcohol, ether, chloroform and glycerin. It is decom- posed by soluble hydrates and carbonates and by strong acids. When ingested, it is decomposed in the stomach and intestines with the lib- eration of guaiacol, and in this wise ex- erts an antiseptic action. It is recom- mended as a substitute for guaiacol in all cases where the latter is indicated. In PROPRIETARY AND SYNTHETIC REMEDIES. the form of ointment it has been recom- mended for acute articular rheumatism. The dose is 5 to 25 grains in capsules or dissolved in warm water. Locally it is used in the form of a 25% ointment with wool fat or with belladonna, zinc cr mercurial ointment. Guaiaperol. (Guaiacol-Piperidine.) This is in colorless crystals soluble in water. It is used mostly in tuberculosis in doses of about 10 grains twice daily. Guaiaquin. (Quinine Guaiacol-Bisul- fonate.) (121) This compound contains both guaiacol and quinine. Quinine alkaloid is present to the extent of 62%, 38% being guaia- col-sulfonic acid, which is equivalent to 24% of pure guaiacol. It is a yellowish, crystalline, hygroscopic powder, very soluble in water, alcohol and dilute acids. It is odorless, has a bitter taste, but not the caustic taste or effects of guaiacol. It is recommended as 'an antipyretic and antitubercular in doses of 2 to 10 grains. Guaiasanol. (Guajasanol.) This is the hydrochlorid of diethyl glycocoll-guaiacol. It is small, colorless, prismatic crystals, having a slight odor of guaiacol and a bitter saline taste. It is soluble in its own weight of water and in 25 parts of alcohol, but insoluble in ether. The aqueous solution should be clear and colorless and give a white precipitate with silver nitrate. It is an antiseptic and antitubercular. It is read- ily absorbed in the system, guaiacol be- ing liberated. It has been recommended for the treatment of tuberculosis, both internally and subcutaneously. It is also recommended as a deodorant and has been used in putrid cystitis. The dose is 15 to 45 grains. Subcutaneously it has been used in amounts of 45 to 60 grains in aqueous solution. Externally it is employed in 1/10 to 2% solutions. Guaisotol. (57) This is a syrup, each fluidounce of which is stated to contain 16 grains of guaiacol. Guaiatonic. (181) This is described as a palatable prepa- ration of guaiacol and creosote with quinine, strychnine and hypophosphites, each fluidram containing 1 minim each of guaiacol and creosote, both as soluble sulfonates, 7/128 grain of quinine, 1/256 grain of strychnine hypophosphite, com- bined with hypophosphites of iron, cal- cium, manganese and potassium in aro- matic sweet solution. Guatannol. (Guatannin.) This is a combination of guaiacol, tannin and cinnamic acid. It is mar- keted in the form of i-grain pills, which are recommended for tuberculosis, glandular enlargements, etc. Guayarsin. This is described as a non-toxic guaia- col-arsenic compound, each 10 grams of syrup containing .005 gram of organical- ly combined arsenic and 0.2 gram of guaiacol with cinnamic acid and calcium chlorhydrophosphate. Guilliermond's Sirop Iodotannique. Extract of rhatany g. 1 Tincture of iodin g. 2 Simple syrup g. 100 Dissolve the extract in the syrup and add the tincture. This preparation is cloudy. If a clear syrup is wanted, dissovle the extract first in a little water, filter the solution, then add the syrup and the tincture. — Hager. Guindre's Sal Aperiens. Sodium sulfate, dried av.oz. 2 Potassium nitrate gr. 18 Tartar emetic gr. 1 — Hager. Gunther's Sedative Pills. According to Parson in Hager, these are composed essentially of Asafetida parts 50 Extract of valerian parts 50 Extract of belladonna parts 3 Castor parts 2 Zinc oxid part 1 Each pill weighs i l /z grains. Gurmin. This is a name applied to a serum in- tended for the cure of glanders in horses. 756 THE STANDARD FORMULARY Gynecol Ointment. (94) This is stated to contain Hamamelis virginica, Verbascum thapsus, Calendula officinalis, Quercus rubra, aluminum sul- fate, oil of peppermint, and petrolatum. H. H. H. Medicine. The claim of the manufacturers is that this is made of oils of origanum, cedar and hemlock, camphor, iodin, white castile soap, ammonia, and suffi- cient grain alcohol to hold the oils in solution, no oil of mustard or turpentine being used. Haarlem Oil. The following formula for the prepa- ration of Haarlem oil is published by the Dutch Society for the Advancement of Pharmacy: Sulfurated linseed oil part I Rectified oil of turpentine. . .parts 2 Mix and filter. The product is a bright, red-brown, oily liquid. It is not intended that this shall be sold as a substitute for the imported Haarlem Oil. The same society gives the following directions for making the sulfurated linseed oil (also called balsam of sul- fur) : Linseed oil part i Washed sulfur parts 2 Mix and heat them together in a por- celain capsule at a temperature between 120 and 130 C, under constant stirring, until the sulfur dissolves. It produces a dark-brown liquid, having a yellow color in thin layers, and completely soluble in oil of turpentine. Haas' Hog Cholera Remedy. According to a report of the U. S. Dept. of Agriculture, the following is probably the composition of this rem- edy: Powdered soap parts 10 Potassium carbonate parts 5 Red ochre parts 12 Chalk parts 50 Quicklime parts 10 Calcined magnesia parts 13 Hasman. This is a liquid peptonized iron sulfo- cyanid. In anemia and gout, the sulfo- cyanids almost totally disappear, and as these possess bactericidal properties, the use of this preparation was suggested. Hsematogen, Hommel's. This is described as a purified and concentrated hemoglobin, flavored with chemically pure glycerin and malaga wine in the proportion of 4 ounces of glycerin and 2 ounces of wine to each pint. Haemoantitoxin. This is a preparation of Maragliano's tuberculosis antitoxin in combination with alcohol and glycerin, flavored with aromatics. It forms a clear solution of a. wine red color of agreeable taste. It is given as a prophylactic against tuber- culosis in tablespoonful doses four times a day before eating. It is made at the Laboratory of the Institute for Infecti- ous Diseases, Genoa, Italy. Haemo-Cardiacin. (17) This is stated to be composed of "nitrogenized iron, 12 fluidounces, fluid extract of cherry bark (detan.), 4 fluid- ounces, fluid extract of digitalis, 2 fluid- drams. Haemoferrum. (Liquid Oxyhemo- globin.) (187) This is a preparation of purified blood said to contain in each fluidounce 32 grains of oxyhemoglobin in a men- struum containing 12^/4% of alcohol. It is prepared from purified blood and the amount of hemoglobin is determined by assay. It is a dark blood-red liquid, of a pleasant odor and taste. It is used in anemia, chlorosis, convalescence, etc., in doses of 1 to 2 teaspoonfuls 3 or 4 times a day. This is the liquid form, but it is also put up in the pill form, each pill containing 3 grains of haemoferrum. Haemoform. This is another blood preparation which appears as a reddish-brown pow- der, completely soluble in water to form a clear brownish solution. PROPRIETARY AND SYNTHETIC REMEDIES. 757 Haemoglobin. (36) This is described as a solution of hemoglobin in serum albumen. It is also put up in combination with digitalis (containing I minim of fluid extract of digitalis to the fluidram), with cactus (containing 3 minims of tincture of cactus grandirlorus to the fluidram), and with strychnine (contain- ing 1/100 grain of strychnine sulfate to the fluidram). The preparation of hem- oglobin with arsenic is now called "nor- malin," which see. It should also be remembered the name hemoglobin is also applied to the chief constituent of the blood which is marketed as a reddish black powder which is soluble in water. It is given as a hematinic. Haemoglobogen. (143) This is described as "a ferruginous tonic which combines the characters of a predigested nitrogenous food with those of a restorative tonic." It is pre- pared plain, with arsenic (each fluid- ounce contains 1/20 grain of arsenic trioxid), and with arsenic and strych- nine (each fluidounce containing 1/20 grain of arsenic trioxid and 1/40 grain of strychnine citrate.) Haemol. See Hemol. Hsemolin. This is a name given to a mixture of hemoglobin and maltose. Haemo-Neuralin. (17) This is described as "nitrogenized iron" and soda with hypophosphites. Haemo-Mangan. (143) Each fluidounce stated to contain 10 grains of iron "citro-peptonate" and 2 grains of manganese "citro-peptonate" in combination with wine. This is also put up with arsenic each fluidram con- taining 1/30 grain of arsenic trioxid. Hsemoprotagon. (Hsematoprotagon.) This is a hasmolecithin, containing iron and phosphorus in organic combina- tion, and said to be prepared from nerve substance and hemoglobin. It is put up only in tablet form. Haemostasin. This is the name applied to a sub- stance obtained from the suprarenal gland of the sheep, evidently a prepara- tion of suprarenal alkaloid. It is mar- keted in the form of powder and as a 1 :iooo solution. Haemostatin. This is tribromphenol-bismuth of lower bismuth content than xeroform. It is used as a hemostatic. Do not con- found with hemostatin. Hsemostyptic. As made by Brunninghausen's process this is a preparation containing the ac- tive principles of ergot and golden seal. It is recommended in doses of 30 drops 4 times a day. Hagan's Magnolia Balm. According to various analyses this contains zinc oxid, glycerin, water and perfume. Hagee's Cordial of the Extract of Cod Liver Oil Compound. (104) This is stated to represent in each fluidounce Yz fluidounce of cod-liver oil (the fatty portion being eliminated), 6 grains of calcium hypophosphite, 3 grains of sodium hypophosphite, 1/16 grain of saccharin, Yz grain of salicylic acid (from oil of wintergreen), and aromatics. Haggard's Stool Promoter. Buckthorn, coarse powder... gr. 150 Potassium carbonate gr. 45 Sodium sulfate, crystal gr. 22 Sodium chlorid gr. 22 Oil of anise drops 5 Alcohol fl.oz. 2 Water fl.oz. 6 l / 2 Glycerin, to make fl.oz. 16 Mix all but the glycerin, macerate jfor a day or so, agitating occasionally, filter, and to the filtrate 'add the gly- cerin. — Hager. Hall's Hair Renewer. This is the revised formula accord- ing to the manufacturers : Alcohol, 58 THE STANDARD FORMULARY sulphur, bay rum, glycerin, cap- sicum, rosemary leaves, boroglycerin, tea, perfume and water. Halogens Compound Elixir. See Elixir Halogens Compound. Hamburg Plaster. Dieterich's Manual gives the follow- ing: Mother plaster av.oz. 8 Suet av.oz. y 2 Black pitch av.oz. V 2 Amber, powder av.oz. I Peru balsam gr. 45 Melt the first three ingredients, add the amber and balsam, and roll into sticks about 5/8-inch in diameter. Hampton's (Sir John) Vital Restora- tive. This was examined by the chemists of the U. S. Department of Agri- culture. The first part of the medi- cine consisted of one pill of methylene blue. This pill when taken will cause the patient's urine to turn green. This naturally would frighten him so that he would consult with the party who supplied the remedy. The second part of the remedy consisted of pills com- posed of licorice and saw palmetto. Hardy's Ointment. Beef tallow av.oz 1 Castor oil gr. 154 Gallic acid gr. 13 Vanilla tincture. . . .enough to flavor — Bouchardat. Hartman's Crimson Salt. Borax part 1 Potassium permanganate. .. .part 1 Salt (common) parts 6 Alum parts 8 — Frerksen. Dr. Haskell's Enteritis Tablets. Each tablet is stated to contain Copper arscnite gr. 1/100 Corrosive sublimate gr. 1/100 Morphine sulfate gr. 1/100 Hayden's Uric Solvent. See Uric Solvent. Hayden's Viburnum Compound. This was stated by the manufacturers lo contain the active principles of vi- burnum opulus, dioscorca villosa, Scu- tellaria lateriflora, and a combination of aromatics. Hayes' Acid Hypophosphites. (95) This is described as an acid solution of the hypophosphites of calcium, po- tassium, sodium, iron, manganese, qui- nine and strychnine with hypophos- phorous acid. Hazeline. This is stated to be an alcoholic dis- tillate from witch-hazel bark. Headine. Acetanilid 68.7% Sodium bicarbonate 2>i-2>% — Dr. Schneider's analysis. Hecto Pepsin. (133) This is described as a highly concen- trated pepsin liquid form for the ready manufacture of wines, -elixirs, and other liquid preparations of pepsin. Hedonal. This is a urethane differing from ethyl carbonate U. S. P. in that the ethyl radicle has been replaced by the radicle methylpropylcarbinol. It is a white, crystalline powder, of a faint, aromatic odor and taste, soluble in 120 parts of water at 37° C, more soluble at higher temperatures, also readily sol- uble in alcohol, ether, chloroform and other organic solvents. It is incompat- ible with alkalies and their carbonates and bicarbonate. It appears to have greater hypnotic power than urethane. It is said not to be followed, by bad after-effects, and is recommended in insomnia due to mental overwork or nervous excitement occurring in neu- rasthenia or hysteria. The dose is 15 to 30 grains, administered dry, followed by a swallow of water, or in wafers or capsules. Helcosol. (Bismuth Pyrogallate.) A yellow, amorphous, odorless, taste- less powder containing 48% bismuth oxid. It is insoluble in water and alcohol, slightly soluble in diluted hydro- chloric acid; an internal and external antiseptic like salol or dermatol. Dose : 5 to 15 grains in powders or capsules. PROPRIETARY AND SYNTHETIC REMEDIES. 7 59 Helfin. (96) These are vermifuge capsules con- sisting of i part of oleoresin of male fern and 2 parts of castor oil. These are accompanied by other capsules con- taining 3 grains of a mixture of 10% of oil of turpentine and 90% castor oil. Helenin. (Alantol — Elecampane or Inula Camphor.) This is in white, acicular crystals, insoluble in water, readily soluble in hot alcohol, ether and oils. It is used as an anticatarrhal in chronic bronchitis, phthisis, coughs with pain, etc., and as an antiseptic in diphtheria, etc. Dose: % grain 10 times daily, in pills. Helgotan Bromate. This is a brom-tannin-methylene com- pound containing 20% of bromin. It is a yellowish-brown, odorless and taste- less powder which is used in the sanie way as bromocoll. Helmbold's Extract Buchu. The following was given as an au- thentic formula by Dr. F. E. Stewart in D. C: Buchu av.oz. 1 Cubebs gr. 180 Digitalis gr. 50 Alcohol fl.oz. 2y 2 Water, to make fl.oz. 15 Licorice gr. 50 Caramel gr. 75 Essence of peppermint. . . .drops 38 Molasses fl.dr. 5 ^ Helmitol. (Hexamethylenamine Methylenecitrate.) This is a white crystalline powder melting with decomposition at about 165 ° C, and of an agreeble acidulous taste and acid reaction. It is soluble in about 10 parts of water but almost insoluble in alcohol and ether. Acids and alkalies decompose it with the liber- ation of formaldehyde. It is a urinary antiseptic and germicide which is claim- ed to be more prompt and energetic in its action than hexamethylenamine, acting equally well whether the urine be acid or alkaline. It is recommended in cystitis,- pyelitis, urethritis, phospha- turia, also as an urinary antiseptic in typhoid and in the latter stages and chronic forms of gonorrhea. The dose is 10 to 15 grains. Helonia Tablets. (146) Each tablet is stated to contain Extract of opium gr. % Extract of helonias gr. ^2 Extract of henbane gr. 1 Salicylic acid gr. 1 Tannic acid gr. 2 Boric acid gr. 3 With thymol, eucalyptol and alum. They are recommended for leucorrhea. Helonias Cordial. (131) Each fluidounce is stated to contain the active principles of 15 grains each of helonias, cramp bark, and blue colosh, and 60 grains of mitchella. It is rec- ommended for various female diseases. Helthin. (178) This is a substance used for testing drinking water. Hemoboloids. (158) Each tablespoon ful is stated to rep- resent Nucleo-proteids and proteids... 4 % Ferric oxid 0.6% Bone marrow extract 5 % Nuclein gr. 1/10 Alcohol 17 % There is also an arseniated form which contains 1/40 grain of arsenous acid and 1/80 grain of strychnine. The iron present in a tablespoonful is stated to be equivalent to 20 minims of tincture of ferric chlorid. Hemapeptone. (52) This is described as a preparation of "albumose-peptone" and hematin. It is also stated to contain 11% of alcohol. Hematic Hypophosphites. This is a compound syrup of hypo- phosphites made by different manufac- turers. As commonly made each fluid- ounce contains Potassium hypophosphite gr. i l A Ferrous hypophosphite gr. ij4 Calcium hypophosphite gr. 1 Manganese hypophosphite gr. I Quinine hypophosphite gr. 7/16 Strychnine hypophosphite. ...gr, \i •60 THE STANDARD FORMULARY As made by one manufacturer it con- tains in addition, I grain of sodium hypophosphite. Hematothyroidine. This is a liquid preparation of thyroid gland. Hematoxylin. This is in yellowish or yellowish- brown crystals of a sweet taste. It is sparingly soluble in water, more soluble in alcohol or ether. It is used as a stain in microscopy. Hematysin. (181) This is stated to be made from the fresh plants Stillingia sylvatica, Smilax sarsaparilla, Phytolacca decandra, Lappa minor and Xanthoxylum carolinianum. Hemec Tablets. (52) These are stated to contain y 2 grain of hematin, V/% grains of nux vomica, and 1/120 grain of arsenous acid. It is recommended in malaria and other ailments characterized by impoverish- ment or loss of blood. Hcmicranin. This is a mixture of 5 parts of phenacetine, 1 part of caffeine and 1 part each of citric acid. It is used in migraine, headache, neuralgia, etc. Heminal. (159) This is described as a 'blood-iron albu- minate." It is stated to contain all the soluble albuminates and salts of blood without the objectionable excretory products. It is marketed only in 2-grain tablets. It is recommended as a hematinic in anemia, chlorosis, convalescence, etc. Hemisine. (Burroughs, Wellcome & Co., Mfrs.) This is described as the active princi- ple of the suprarenal gland. It is in a dry, stable, soluble form and solutions may be made from it. It is marketed in tablets of various strengths, both plain and in combination with sodium chlorid and eucaine hydrochlorid, also in the form of rectal suppositories. Hemogallol. (130) This is an organic iron compound produced from blood by reduction of its hemaglobin by means of pyrogallol. Fresh defibrinated blood, suitably diluted with water is mixed with an equal amount of a saturated solution of of pyrogallol which causes the precipi- tation of a voluminous precipitate which is separated, washed with water to re- move pyrogallol and finally with alcohol. It is a reddish-brown, almost tasteless powder, insoluble in water, alcohol, etc. It is recommended for anemia, chlorosis, chronic nephritis, diabetes, and in con- valescence. It is said to be very easily transformed into the blood-coloring matter by the organisms of debilitated persons. The dose is 4 to 8 grains, one- half hour before meals. Hemoglobin. See Haemoglobin. Hemol. (Haemol — Reduced Hemoglo- bin — Parahemoglobulin.) This is an organic iron compound produced from blood by reduction. Neu- tralized blood is shaken with zinc dust and water and the zinc removed from the product of the reduction. It is a dark-brown, almost tasteless powder, insoluble in water, alcohol, etc. It con- tains traces of zinc oxid. It is claimed to be useful in anemia, chlorosis, etc., in doses of 2 to 8 grains. Hemol, Arsenated. See Arsenhemol. Hemol Bromid. See Bromo-Hemol. Hemol, Cuprated. See Cupro-Hemol. Hemol, Iodized. See Iodo-Hemol. Hemonervine. (181) This is put up in tablet form, each tablet being stated to contain Calcium phosphoglycerate. . .gr. 2 Hemoglobin gr. 1 "Soluble iron" gr. H Strychnine nitrate gr. 1/100 With blood salts and stomachics. PROPRIETARY AND SYNTHETIC REMEDIES. 761 Hemoquinine. (Compound Elixir of Peptonate of Iron, Manganese and Quinine with Arsenic.) (179) One fluidounce is stated to contain 34 grains of so-called peptonate of iron (made by adding ammonio-citrate of iron to freshly prepared peptone of egg albumin) and 8^ grains of so-called peptonate of manganese together with 5 grains of quinine peptonate (equival- ent to 2.3 grains of quinine- sulfate), and 1/9 grain of sodium arsenate in a menstruum containing 20% of alcohol with glycerin and aromatics. The dose is 2 fluidrams 3 times a day. Hemorrhoidic Pills. See Pil. Hemorrhoidica. Hemostatin. (211) This is described as a "pure solution of the crystallized chlorid of the active hemostatic and blood-pressure raising principle of the suprarenal gland (1:1000)." It is also furnished in the powder form. Do not confound this with haemostatin. Henry's Carbolic Salve. Carbolic acid gr. 16 Oil of bergamot drops 6 Oil of lavender drops 3 Simple cerate av.oz. 2 — Hager. Henry's Cosmetic. Oil of lavender part 1 Oil of rosemary part 1 Oil of bergamot part 1 Oil of lemon parts 3 Alcohol parts 180 — Hager. Ifenry's Magnesia. This is a heavy calcined magnesia. Henry's Three Chlorides. (Liquor Ferrisenic, Henry's) (formerly called Elixir Three Chlorides.) (97) Each fluidram is stated to contain Y% grain of iron protochlorid, 1/128 grain of mercury bichlorid, and 1/280 grain of arsenic chlorid, in a cordial of cali- saya alkaloids. Henry's Tri-Iodides. This is stated to contain 1/20 grain of colchicine, 1/10 grain of decandrin, Yz grain of solanin, 10 grains of sodium salicylate and iodic acid (equal to 7/32 grain of iodin) in 2 fluidrams of "aro- matic cordial." Hensel's Tonicum. Marble dust g. 30 Formic acid (sp. gr. 1.20) g. 55 Ferrous sulfate g. 21 Solution of tersulfate of iron (sp. gr. 1.318) g. 100 Glacial acetic acid g. 100 Alcohol g. 400 Water g. 600 Dissolve the marble dust in a mix- ture of the formic acid and half the water and the iron salt and solution in the acetic acid and the remainder of the water. Mix the two solutions, add the alcohol, and filter. Acetic ether as formed on standing but it is advisable to add 15 grams of it immediately upon making the preparation. This is a fer- ruginous tonic favored largely by hom- eopathists. — Ph. Ztg. Heparon. This is an organotherapeutic substance obtained by the action of pancreatic juice on the liver of the ox. It is said to be useful in diabetes as it aids the liver to split up grape sugar. Hepatosmene. (215) This is stated to be composed of 70 grains of sodium phosphate and 5 grains of sodium sulfate to the dram. Hermophenyl. (Mercuric-Sodium Phenyldisulfonate.) This is a white, amorphous powder, soluble in 7 parts of water, and con- taining 40% of mercury. It is strongly antiseptic and bactericidal, and in spite of containing so much mercury is rec- ommended as a substitute for iodoform and salicylic acid. It is said to have no caustic action on the skin or mu- cous membranes. When taken intern- ally the dose is H to ^2 grain 3 times a day. Heroids. (63) Each dessertspoonful is stated to con- tain THE STANDARD FORMULARY Heroin gr. 1/12 Terpin hydrate gr. 2 Syrup of wild cherry m. 15 Balsam of tola and glycerin., q. s. Heroin. (Diacetyl-Morphine.) Heroin Hydrochloride Heroin is a synthetic alkaloid obtained by acetylizing morphine. These two substances are white, odorless powders, of a bitter taste. Heroin is practically insoluble in water, sparingly soluble in cold alcohol, readily soluble in warm alcohol or chloroform. The hydrochlorid is soluble in 2 parts of water and is also readily soluble in alcohol. On warming with mineral acids, both com- pounds are decomposed, morphine being reformed. These substances are directed to be kept in a cool, dry place, in well- corked bottles. They are used as sub- stitutes for opiates \n mixtures for coughs, asthma, phthisis, bronchitis, etc. The dose is 1/24 to 1/12 grain 3 times daily. On account of its solubility, the hydrochlorid is generally preferred. Heroline. This is a 33 r A7o emulsion of petrola- tum containing also 1/16 grain of heroin hydrochlorid and 8 grains each of cal- cium and sodium hypophosphites in each fluidounce. Heromal. (Malt Extract with Heroin and Hypophosphites.) (179) Each dose of 2 fluidrams is stated to contain 1/48 grain of heroin and y£ grain of sodium hypophosphite in a menstruum of malt extract with 6% of alcohol. The dose is 2 fluidrams every 3 or 4 hours. Herophosphites. (179) This is stated to contain hypophos- phites of sodium, potassium, calcium, iron, manganese, quinine and strychnine with heroin hydrochlorid. The solution is stated not to contain sugar. Heroterpine Elixir. See Elixir Heroterpine. Herpicide. According to analysis by the New Hampshire Board of Health, this leaves 2^2% of residue upon evaporation, about 1% of which is salicylic acid with some borax or boric acid; it shows no alka- loids or vesicants ; and it contains 56.27c of alcohol, practically all of which was found to be wood alcohol. Hetocresol. (Cinnamylmetacresol.) This is a white or yellowish powder, insoluble in water but soluble in chloro- form, ether or hot alcohol. It is rec- ommended by Prof. Landerer for in- jection in tuberculosis. Hetoform. (Bismuth Cinnamate.) This is a white powder of a cinna- mon-like odor, obtained by decomposi- tion between bismuth nitrate and sodium cinnamate. Hetol. (Sodium Cinnamate.) (103) This may be prepared by saturating a hot aqueous solution of sodium car- bonate with cinnamic acid, evaporating and crystallizing. Cinnamic acid is ob- tained from balsam of tolu or ma}' be produced synthetically by heating to- gether benzaldehyde, sodium acetate and acetic anhydride. Sodium cinnamate is a white crystalline powder, soluble in 20 parts of water, the solution being faint- ly alkaline. On boiling, the alkalinity be- comes stronger on account of the de- composition of the cinnamate to form carbonate. It is incompatible with acids and with oxidizing agents, such as po- tassium permanganate. Balsam of peru, cinnamic acid and sodium cinnamate are recommended by Prof. Landerer for the treatment of phthisis, these substances being injected intravenously. The dose of the cin- namate is 1/60 .grain, gradually in- creased to Yz grain, in a 1 to 5% solu- tion, injected intravenously 3 times a week for long periods, say from 3 to 18 months. Hetol-Caffeine. (Caffeine Sodiocinna- mate.) This is prepared by warming 106 parts of caffeine and 85 parts of hetol with 400 parts of water on a water bath, and evaporating the solution to dryness, It PROPRIETARY AND SYNTHETIC REMEDIES. 763 is an amorphous, white, odorless, bitter powder, soluble in 2 parts of w T ater and 50 of alcohol. Hetralixi. This is a new hexamethylenetetramine derivative of which it contains 60% It is in needle-shaped crystals, soluble in 4 parts of hot water and 14 parts of cold water. It is used in crytitis in doses of 5 grains 3 times a day. Hexamethylenamine. See Hexamthylenetetramine. Hexamethylenamine Methylenecit- rate.) See Helmitol. Hexamethylenetetramine. This is known in the U. S. P. as hexamethylenamine and commercially by a great variety of names such as cystogen, cystine, cystamine, aminoform, formin, urotropin, uritone, uroformin, hexamine and many others. It is a condensation product obtained by the action of ammonia upon formaldehyde. It is in colorless, odorless crystals or whitish powder, of a somewhat sweet- ish and warming taste. It is soluble in about 1V2 parts of cold or hot water and in 10 parts of alcohol. The aqueous solution is alkaline to litmus paper. Hot water and acid syrups are liable to de- compose it. It should be kept in well- stoppered bottles. It is used as a uric acid solvent and as a urinary antiseptic and has been gaining in popularity since its introduc- tion. It is prescribed in cystitis, ure- thritis, bacteriuria, gonorrhea, prosta- titis, etc. The dose is 5 to 15 grains, well diluted with water, 2 or 3 times daily before meals. Hienfong Essence. I. Bay leaves g. Laurel berries g. Camphor g. Oil of peppermint g. Oil of crisped mint g. Oil of anise g. Oil- of fennel g. Oil of lavender g. 1 1 15 15 10 2.5 2-5 2.5 Oil of rosemary g. 2.5 Ether . .g. 80 Alcohol (90% ) g. 2000 Color green by adding chlorophyll or macerating with grass. II. According to Hager, Schoeffer's preparation consists of a tincture of 5 parts each of bay leaves and laurel ber- ries, 15 parts of ether and 200 of alco- hol, and to this is added 1^% of cam- phor, 1% each of oils of crisped mint and peppermint and J /i% each of oils of anise, fennel, lavender and rosemary. III. Kaupitz's formula : Oil of caraway g. 10 Oil of peppermint g. 32 Oil of anise drops 80 Balsam of peru g. 20 Camphor ^ g. 24 Alcohol (90%) g. 3200 These formulas are from Ph. Ztg. Hippol. (Methylene-Hippuric Acid.) (178) This is an odorless, colorless, and tasteless prismatic crystals, sparingly soluble in water. It is recommended as a urinary antiseptic in bacterial dis- eases of the urinary tract. Formalde- hyde is liberated in the system. The dose is 20 grains 4 times a day. It is marketed in powder and in 15-grain tablets. Hirudin. This is a preparation obtained from the leech and is said to represent the antistyptic properties of this animal. It is made by extraction of the head phar- yngeal rings and lips. It is in brown scales or masses, soluble in water but insoluble in alcohol or ether. It is used in the treatment of some diseases of women and wherever the coagulation of blood is to be prevented. Histogenol. This is described as nucleinic acid de- rived from herring brine and treated with 20% of sodium methyl-arsenate. It is used as a remedy for tuberculosis. Histosan. (Guaiacol Albuminate.) This is a light brown powder, of a faintly aromatic odor and taste, and is '64 THE STANDARD FORMULARY soluble in water. It is said to be bet- ter tolerated by the stomach than other gnaiacol compounds. The dose is 4 to 8 grains. It is also marketed in the form of a 5% syrup, the dose of which is a teaspoonful 3 to 6 times a day. It is used in pulmonory tuberculosis and in diarrhea. Hitt's Headache Powders. These are stated to contain in each 7^ grains: Acetanilid gr. 4% Theine gr. 6/10 Other ingredients gr. 2 6/10 H.-M.-C. (Abbott.) See Hyoscine, Morphine and Cactin Comp. Hobb's Kerosene Liniment. Oil of origanum fl.dr. 4 Tincture of opium fl.dr. 4 Tincture of stramonium fl.dr. 4 Tincture of arnica fl.dr. 5 Spirit of camphor fl.dr. 5 Aromatic spirit ammonia fl.dr. 6 Chloroform fl.oz. 1 Kerosene fl.oz. 2 — Kilner. Holadin. (70) This is described as "an extract of the entire pancreas gland, presenting all the constituents both of the digestive and the internal secretion." It is stated to contain the tryptic, amylolytic and lipolytic ferments, also lecithin and nu- clein. It is put up in gelatin capsules, each one containing about 3 grains. The dose is one capsule about 3 hours after meals and one at bedtime. Holloway's Ointment. This preparation was examined by the French government chemists who stated that it is composed of butter, lard, white and yellow wax, and Ven- ice turpentine. According to Cooley's Cyclopedia, the following is the for- mula generally employed: Fresh butter, free from water or salt av.oz. 12 Yellow wax av.oz. 4 Resin av.oz. 3 Vinegar of cantharides fl.oz. 1 Balsam of fir av.oz. 1 Expressed oil of mace gr. 30 Peru balsam or liquid styrax drops 10 or 12 Melt the butter, wax and resin, add the vinegar, allow the whole to sim- mer for 10 or 12 minutes, or until the moisture is nearly evaporated; allow to cool somewhat, add the remaining ingredients, and stir until cool. Holloway's Pills. The following is given by Cooley : Aloes parts 2 Jalap part 1 Ginger part 1 Myrrh part 1 Make into a mass with mucilage and divide into 2-grain pills. Dorvault gives the following as the composition of these pills as found on analysis : Socotrine aloes gr. 60 Rhubarb gr. 25 Pepper gr. 7 Saffron gr. 3 Sodium sulfate gr. 3 Make 144 pills. The pills are rolled in powdered gin- ger. Holman's Liver Pad. This is similar : May apple root oz. l / 2 Leptandra root oz. l / 2 Fenugreek oz. y 2 Guaiac resin oz. V/ 2 Bayberry bark dr. 2 Red cinchona bark oz. 2 Oil of eucalyptus fl.dr. 2 Grind the solids to powder, mix with them the oil and make into a pad, using cotton cloth of suitable thickness as an envelope. — Kilner's Form. Holocaine Hydrochlorid. This is in small, colorless, odorless and faintly bitter crystals, producing a transient numbness on the tongue. It is soluble in 50 parts of water and freely soluble in alcohol. It should form a clear, colorless solution which is neu- tral or faintly alkaline. It is incompat- ible with alkalies and their carbonates and the usual alkaloidal reagents. It is a- local anesthetic like cocaine but hav- ing the advantage of quicker effect and PROPRIETARY AND SYNTHETIC REMEDIES. 765 antiseptic action. 5 minims of a 1% solution when instilled into the eye are usually sufficient to cause anesthesia in from 1 to ro minutes. It is more toxic than cocine. Aqueous solutions are decomposed even by the alkali con- tained in glass bottles, so that solu- tions should be dispensed either in por- celain containers or in bottles which have previously been boiled in hydro- chloric or sulfuric acid and thoroughly rinsed in distilled water. Holzinol. This is a mixture said to consist of I part of formaldehyde, 20 parts of menthol and 25 parts of wood alcohol. It is recommended as a disinfectant in 3% solution. Homatropine Hydrobromate. This is in white, non-hygroscopic leaf- lets, which are soluble in 10 parts of water. It is used chiefly as a mydriatic, being less irritating, less liable to pro- duce systemic disturbance, and is less persistent than atropine. It is used in 1% aqueous solution. Hommel's Haematogen. See Hsematogen. Honthin. This is described as a keratinized al- bumin tannate (or tannin albuminate). It is a grayish-brown, odorless, tasteless powder, insoluble in water. It is used as an intestinal astringent. It is insol- uble in the acid secretion of the stomach but is gradually decomposed by the alka- line fluids of the intestine. The dose for adults is 15 grains, for children 3 to s grains, several times daily. Hooper's Female Pills. The following is the formula advo- cated by the Philadelphia College of Pharmacy some year ago : Aloes, Barbadoes gr. 96 Ferrous sulfate, dried gr. 25 ^xtract of black hellebore. . .gr. 24 '^rrh gr. 24 3oap gr. 24 Canella gr. 12 Ginger gr. 12 Beat them well together into a mass, with syrup or water, and divide into pills, each containing 2^2 grains. Hop Bitters. The following is said to be similar : Hops av.oz. 4 Orange peel av.oz. 2 Dandelion av.oz. 2 Buchu av.oz. 1 Mandrake av.oz. y 2 Sugar av.oz. 16 Alcohol fl.oz. 16 Water, to make pints 8 Macerate the drugs in coarse powder in the alcohol and 7 pints of water, at a warm temperature, for 8 days. Ex- / press and dissolve the sugar in the liquid, to which add water, if necessary, tc make 8 pints, and strain. — W. D. Hopogan. This is a name for magnesium dioxid. See also Biogen. Horlick's Infant's Food. The following is an abstract of the patent specifications for this prepara- tion: Macerate equal parts of barley malt and ground wheat (groats) in fresh cow's milk, and stir until it forms a loose, soft mash. This mash is then placed in a jacketed kettle and the heat gradually raised to 150 F., and kept agitated for half an hour; the starch is thus transformed into dextrin and grape sugar by the diastase of the malt. The temperature is now raised to 170 C, for 15 minutes, after which the mixture is pressed to remove the liquid which is evaporated in a vacuum pan to a dry extract, and is then powdered. Horner's Rheumatic Lightning. The following makes a somewhat sim- ilar article : Fl. ext. colchicum seed. . . . .fl.dr. 1 Fl. ext black cohosh. fl.dr. 4% Potassium acetate gr. 128 Sodium salicylate gr. 256 Alcohol fl.oz. 2 l / 2 Water, to make fl.oz. 16 — N. I. Horsford's Acid Phosphate. Each fluidram is said to contain S l A grains of free phosphoric acid, 3 grains 766 TTTE STANDARD FORMULARY of calcium phosphate, y 2 grain of mag- nesium phosphate, J4 grain of potassium phosphate, and 1/6 grain of iron phos- phate. The total amount of phosphoric acid, free and combined, in one fluid- dram, is said to be 7 grains. Hostelley's Wine of Cod Liver Oil Comp. Each teaspoonful is stated to repre- sent Cod liver oil -. .m. 21 Arsenic chloric! gr. 1/200 Mercury bichlorid gr. 1/128 Iron protochlorid gr. ^4 Port wine and vegetable flavoring. Howe's Compound Damiana Tablets. These are stated to be composed of phosphorus, extracts of nux vomica, damiana, coca, saw palmetto, and corn silk, and "ferri soluble." The manu- facturers state that they use "fresh green extracts." Howe's Kidney Tablets. These are stated to be composed of extracts of asparagus, buchu, couch grass, and corn silk, and oil of juniper and nitre. The manufacturers state that they use "fresh green extracts." Hoyt's Hiawatha Hair Restorative. According to Chandler's analysis, this is a 1% ammoniacal solution of silver nitrate. Xo other metals were found. Hudson's Honey of Elm. This is a tooth paste containing pre- cipitated chalk, powdered pumice stone, glycerin, oil of clove, oil of winter- green, and simple syrup. — Era Form. Hufeland's Nerve Tea. Valerian root. Avens root. Peppermint herb. Orange flowers, each, equal parts. — Hager. Hunn's Drops with Chloroform. (17) Each fluidounce is stated to contain Oil of anise fl.dr. 1 Oil of clove fl.dr. 1 Oil of peppermint fl.dr. 1 Oil of cajeput fl.dr. 1 Chloroform m. 15 Hunter's Red Drops. Mercuric chlorid gr. 10 Hydrochloric acid drops 12 Comp. tincture lavender fl.oz. 1 Mix, carefully dissolving the mercuric chlorid. The dose is 5 to 20 drops. It has been used as an alterative in syphilitic dis- eases. Husband's Magnesia. This is heavy calcined magnesia. Huxley's Glycerophosphates. See Glycerophosphates Syrup and Tablets. Huxley's Menthol and Wintergreen Cream. This is an antirheumatic cream in collapsible tubes, stated to contain 10% each of menthol and wintergreen. Hydracetin. (Pyrodine — Acetyl- pheny lhy dr azin. ) This is in colorless, odorless and taste- less crystals, soluble in about 50 parts of water and very soluble in alcohol. It is an antipyretic, used in rheumatism and febrile complaints. Being some- what toxic it is not much used intern- ally but is used externally mostly as a 10% ointment in psoriasis. The in- ternal dose is Vi to 2 grains 3 times a day. Hyperphosphine, Prunier's. This is described as a pure phospho- glycerate of lime prepared according to the original process of Portes and Prunier. It is supplied in three forms, granulated, syrup and cachets. Hypo-Quinidol Pills. See Pil. Hypo-Quinidol. Hydragogin. This is a preparation stated to con- tain 3 parts of tincture of digitalis, 5 parts of tincture of stramonium, scilli- toxin and scillipicrin, the active princi- ples of squill, and 1 part of oxysaponin from Hermaria glabra. It causes in- tense diuresis without severe catharsis. It is recommended as a diuretic in dropsy, ascites, etc. It is also used as PROPRIETARY AND SYNTHETIC REMEDIES. 767 a cardiac tonic. The dose is 10 to 15 drops every 3 or 4 hours. Hydrarg-Iodo-Nucleoid. This is put up in tablets, each con- taining 5 grains of Iodo-Nucleoid and y 2 grain of Hydrarg-Nucleoid. Hydrarg-Nucleoid. (63) This is described as a compound of mercury with nuclein, containing 10% of the former. One grain is said to equal 1/6 grains of mercury protiodid. It is said to be a tasteless, non-irritating substitute for the inorganic salts of mercury. It is put up in Yi and i-grain tablets. Hydrargyne. This is a bibulous paper saturated with corrosive sublimate, and intended for the extemporaneous preparation of an antiseptic solution. Hydrargyrin. This is a mercurial ointment made with lanolin as the vehicle. — Coblentz. Hydrargyrol. (Mercury Paraphenyl- sulfonate.) This is in reddish-brown scales, of aromatic odor, readily soluble in water and glycerin. Its advantages over other mercuric compounds are that it is not corrosive, is but slightly toxic, does not precipitate albumen and does not corrode instruments. For surgical pur- poses the solution should be of the strength of 1 to 2,500. Hydrastine. This is an alkaloid derived from gold- en seal. It is in white crystals, easily soluble in alcohol, ether and chloroform, but almost insoluble in water. It is an alterative tonic, antiperiodic, etc. It is not used externally on account of its in- solubility. The dose is ^ to 1 grain. The hydrochlorid is the principal sol- uble salt. It is a white crystalline pow- der readily soluble in water. It is used as an astringent in gonorrhea, conjunc- tivitis, leucorrhea, etc. ; also as an ex- ternal application in dermic hyperidrosis, acne, seborrhea, etc. As an astringent it is used in 1/10 to 6/10% solution and as an ointment or lotion containing 1% of alkaloid for skin application. Hydrastinine Hydrochlorid. This is a salt of artificial alkaloid I derived from hydrastine. It is in lemon yellow, hygroscopic, odorless, bitter cry- \ stals or crystalline powder, very soluble I in water and alcohol. It should be kept ! in well -stoppered bottles. ; It is used as an uterine hemostatic and 1 vaso-constrictor in hemorrhages, con- gestive dysmenorrhea, metorrhagia, etc. The dose is J4 grain 4 or 5 times dailv with sugar, in capsules. As a subcu- taneous injection, 8 to 15 drops of ? 10% aqueous solution are used once daily. Hydrastis and Calisaya Tonic. (218) Each fluidounce is stated to contain 32 grains each of golden seal and ca- lisaya, 16 grains of gentian, and 4 grains of nux vomica. Hydrastoids. (63) This is described as a palatable stand- ardized solution of the active princi- ples of Hydrastis canadensis, each tea- spoonful containing 10 grains of golder seal. Hydriodic Ether. See Ethyl Iodid. Hydrobromic Ether. See Ethyl Bromid. Hydrocerin. This is an ointment vehicle consisting of wax, petrolatum and water. Hydrochinone. (Hydroquinone — Paradioxybenzene.) This is in colorless prisms soluble in 17 parts of water, easily soluble in hot water, alcohol and ether. It is an anti- septic and antipyretic like resorcin. In 1 to 3% solution it is used in conjunc- tivitis, gonorrhea, etc. It is used in rheu- matism, fevers, etc., in doses of 5 to 15 grains. It is also used as a photographic developer. The solution should be ex- cluded from air and light. 768 THE STANDARD FORMULARY Hydrocine. This is the formula as given by the manufacturers in their literature: Hyper-oxidized hydro-carbon (vegetable) gr. 28 Pure rock sugar gr. 8 Powdered pancreatin gr. 1/20 Hydrocyanate of Iron. (194) This is put up in y 2 and i-grain tab- lets, also in combinations with arsenic, with henbane, with horse nettle, with nux vomica, and with valerian. Hydrogol. This is an aqueous solution of col- loidal silver. Hydroleine. (Hydrated Oil.) This is stated to contain cod liver oil, pancreatin, etc., and 1 grain of sa- licylic acid to each fluidounce. Hydrosol. This is an aqueous solution of col- loidal mercury. Hydroxylamine Hydrochlorid. This is in colorless, crystalline plates, very hygroscopic, readily soluble in water and alcohol ; used externally like chrysarobin and pyrogallic acid in 1/10 to 4/10 solution for psoriasis lupus, etc. Used also as a photographic developer. Hydrozone. This is described as a 30-volume aque- ous solution of hydrogen peroxid. Hydronal. This is a polymeric form of anhydrous chloral, known also as viferral. It is a white powder, sparingly soluble in cold water, more freely in hot water. It is used as a hypnotic in doses of 15 grains. It is marketed in the form of 15-grain tablets. Hymosa. (209) This is stated to embody frangula, actea spicata, stellaria media, francisca uniflora, passiflora incarnata, rhus tox, and Phytolacca. Hyoscine Hydrobromate. This is in colorless, permanent, odor- less, acrid crystals which are soluble in iH parts of water and in 16 of alcohol; but slightly soluble in ether and chloro- form. It is used as a hypnotic and sedative in insanity, chorea, alcoholic tremor, etc., also as an anaphrodisiac, antisialogogue, mydriatic, etc. It is used but little externally. The dose as a hypnotic in insanity is 1/30 grain; as a sedative, 1/150 to 1/100 grain. Subcu- taneously it is administered as a hyp- notic in doses of 1/120 to 1/60 grain; as a sedative, 1/300 to 1/200 grain. Hyoscine, Morphine and Cactin Comp. (1) There are hypodermic tablets intended for surgical and obstetrical anesthesia, each one containing hyoscine hydro- bromid, gr. 1/100, morphine hydro- bromid, gr. %, a nd cactin (Abbott), "the active principle of Cactus grandiflorus," gr. 1/67. Hyoscyamine. This is in white, silky, permanent crystals, sparingly soluble in water, read- ily soluble in acidulated water, alcohol, ether and chloroform. In its action it is like atropine, but is used chiefly as a hypnotic in mental disorders ; as an anodyne and antispasmodic in asthma, epilepsy, colics, chorea, etc. Dose (ordinary) : 1/120 to 1/30 grain as a hypnotic for the insane. Its anti- dotes are the same as for atropine. The soluble salts hydrobromid and sulfate are used, both of which are very freely soluble in water. Hyos-Sco-Deine. (48) This is stated to contain hyoscyamine, scopolamine, piperidin, strychnia, pilocar- pine, caffeine and codeine. Hyos-Sco-Phine. (48) These are stated to contain hyoscya- mine, scopolamine, piperidine, pilocar- pine, caffeine and morphine. Hyper-Samphire. This was analyzed by Kebler of the department of agriculture who found it to be a mixture of sodium chlorid (72%) and sodium salicylate and sul- fite. Other analyses however, showed other results so that different samples PROPRIETARY AND SYNTHETIC REMEDIES. 769 vary in composition. The substance is recommended as an egg preserver.- Hypnal. (Chloral-Antipyrine.) This is prepared by triturating anti- pyrin and chloral hydrate together in molecular proportions, dissolving the re- sultant oily liquid in hot water and al- lowing the solution to cool. It is in colorless crystals or white crystalline powder, soluble in 10 to n parts of cold water, freely soluble in hot water and soluble in 3^ parts of alcohol. It is incompatible with alkalies, their carbonates and bicarbonates and with metallic salts. It is an analgesic and hypnotic resembling chloral in its action but is said to be less liable to produce injurious effects on the vasomotor cen- ter or the heart. The dose is 15 to 30 grains; although supposed to be less toxic than chloral, doses up to 45 grains should be used with caution. Hypnoacetin. This is in colorless crystals which are readily soluble in water but insoluble in alcohol. It is used as a hypnotic and antipyretic in doses of 5 grains. Hypno-Bromic Compound. (211) Each fluidounce is stated to contain Hydrated chloral gr. 96 Potassium bromid gr. 48 Extract of henbane gr. 1 Ext. cannabis indica gr. 1 Morphine sulfate gr l / 2 Hypnone. (Acetophenone.) This is a colorless, oily liquid of peculiar odor and pungent taste. It is only slightly soluble in water, but is readily miscible with alcohol, ether and oils. It is used as a hypnotic, in doses of 2 to 5 minims. Hypnopyrine. Under this name a new remedy has been placed on the European market, which is stated to be a complex chlorine- derivative of quinine. On analysis, how- ever, it has been found (Repert. Pharm.) to be a mixture of already well- known bodies, and not a new com- pound. It is very bitter, soluble in 8 parts of water, also soluble in alcohol and acids. The dose is 4 grains 3 or 4 times a day as an antipyretic and analgesic in migraine, neuralgia and rheumatic pains. Hypophosphites, Hayes' Acid. See Hayes' Acid Hypophosphites. Hypophosphites Solutions. See Solution of Hypophosphites and Solution Hypophosphites Comp. Hypophospholoid. (Syrup of the Mineral and Alkaloid Hypophos- phites.) (17) According to the manufacturers, each fluidram contains sodium and calcium hypophosphites, each J /> grain; iron and quinine hypophosphites, each Yz grain ; and strychnine hypophosphite, 1/96 grain. This preparation is also put up with cherry and with manganese, the latter containing ^4 grain of manganese hypo- phosphite to the fluidram. Hyrgol. (Colloidal Mercury.) (178) This is a dark, solid body, fairly sol- uble in cold water, insoluble in alcohol and ether. The aqueous solution is neutral in reaction and is not corro- sive. The mercury is precipitated in the insoluble condition by acids, alkalies, alkaline earths and salts of the heavy metals. It has been used in syphilis in- ternally in the form of pills and tab- lets and externally as a 10% ointment. The dose is Vi to % grain three times daily. Hysterol. This is the name applied to bornyl valerate when put up in gelatin pearls, each containing 4 grains. Iatrevin. This is a condensation product of menthol and isobutylphenol. It is a clear liquid of an aromatic odor. It is a disinfectant and is recommended for chronic catarrh. Ibit. (Bismuth Oxyiodotannate.) This is a greenish-gray, odorless, tasteless powder, insoluble in ordinary solvents but decomposed in contact with TO THE STANDARD FORMULARY water, iodin being liberated. Light also decomposes it. It is recommended as an external antiseptic in powder form, or in suspension with glycerin and water. Ichthalbin. (Ichthyol Albuminate.) (109) This is a compound of ichthyol-sul- fonic acid with albumin containing 75% of ichthyol. It is a very fine, grayish- white odorless and nearly tasteless pow- der. It is insoluble in water, in the gastric juice or in acid liquids. Its internal action and uses are the same as those of ichthyol, but is said to be free from the unpleasant effects of nausea, eructations, etc. The dose for infants is 2 to 5 grains, elder children, 10 to 15 grains, and adults, 15 to 20 grains. It is used chief- ly for intestinal disorders. Ichthammon. (168) This is the ammonium compound of a sulfo acid obtained from a bituminous mineral by distillation with sulfuric acid and neutralization with ammonia. It has the physical properties of ichthyol. Ichthargan. (Silver-Ichthyol.) This is a compound of ichthyol and silver claimed to contain 30% of metallic silver and 15% of sulfur in combination. It is a brown, amorphous, stable powder, having a faint chocolate-like odor. It is freely soluble in water, glycerin or di- luted alcohol. Its aqueous solution darkens with precipitation of metallic silver when exposed to the light, but is said to remain unchanged in amber-col- ored bottles. It is incompatible with soluble chlorids. It is recommended in all forms of gonorrhea. It is claimed to have a higher content of silver than any other organic silver compound. It is used in 1/25 to 1/5% solution in gon- orrhea, 3/10% solution in posterior ure- thritis, and y 2 to 3% solution in tra- choma, in the latter case being applied with a brush. Ichthermol. (Mercury Ichthyolate.) This is a compound of ichthyolsul- fonic acid and mercury, containing 24% of metallic mercury. It is a dark col- ored, odorless powder, insoluble in wa- ter. Ichtholferrin. (Iron-Ich.th.yol.) See Ferrichthol. Ichthoform. (Ichthyol-Formalde- hyde.) This is a compund of ichthyol and formaldehyde. It is a dark brown, nearly odorless and tasteless and perma- nent powder. It is insoluble with usual solvents. It is used as an antiseptic to arrest intestinal decomposition and in- flammation. It is also used locally in endometritis, in ozena, wounds, ulcers, etc. The dose is 10 to 30 grains. Ex- ternally it is used undiluted, in 30 to 50% triturations and in 10 to 25% oint- ments. Ichtholdine. (Glyceritum Ichthyolis Comp.) (141) Each fluidounce is stated to contain Ichthyol gr. 4 Iodin gr. 1 Sol. phenol gr. 4 Boroglyceride gr. 9 Eucalyptol ■ gr. 1/20 Hydrastine hydrochlorid gr. 1/32 This is used in chronic endometritis, leucorrhea, gonorrhea, erysipelas, etc. Ichthyalum Ointment. (143) The active constituents are stated to be ichthyol, tar, phenol, fir balsam, zinc oxid and alum. Ichthyodin. This is a trade name for a purified ichthyol, said to be free from the sul- fones and volatile oils of the latter. Ichthyol. (Ammonium Sulfichthyo- late.) This consists largely of the ammonium salts of sulfonic acids derived from the tar of a bituminous shale which is found in the Tyrol and which contains the remains of many fossil, fishes. It is a brown, viscid liquid, translucent in thin layers, having a bituminous odor L PROPRIETARY AND SYNTHETIC REMEDIES, 771 and taste. It is soluble in water, misci- ble with glycerin, oils and fats, not solu- ble in either alcohol or ether, but solu- ble in a mixture of equal parts of these two liquids. It contains about 10% of sulfur in natural combination and a fur- ther 7% introduced by the sulfonation. Ichthyol is precipitated from its aque- ous solutions by acids while the fixed alkalies develop the odor of ammonia. It is incompatible with acid and saline solutions, fixed alkalies, their carbonates and iodids, alkaloidal salts, mercuric chlorid, etc. It is recommended internally in phthi- sis, skin diseases, gout, scrofula, nephri- tis, intestinal disorders, etc. Externally it has been applied in erysipelas, burns, chilblains, carbuncles, rheumatism, ivy poisoning, etc., also in uterine and va- ginal inflammation, gonorrhea, etc. In- ternally the dose is 3 to 30 minims, mostly in the form of pills or capsules. Locally it is used in 5 to 50 ointments and in 1 to 3% solutions for gonorrhea. Ichthyol-Calciuxn. (Calcium Sulfich- thyolate.) This is put up in i^-grain tablets, which are odorless and tasteless. Ichthyol-Sodium. This is a dark brown mass, more solid than ammonium ichthyol, but oth- erwise having similar physical proper- ties. It contains 15% of sulfur. It is used for the same purposes as ichthyol. Its firmer consistence makes it more suitable for making pills. Ichthyol-Salicyl. This is a name for three mixtures containing respectively %., Yz and ^ of sodium salicylate. It is a brown, hygro- scopic powder, not completely soluble in water. It is used in rheumatism, tuber- culosis, etc., internally and externally. Ichthyolodin. (Ichthyol-Piperazine.) This is a brownish-black powder hav- ing little odor or taste. It is insoluble in water but is soluble in alkaline solu- tions. It is recommended in the treat- 49 ment of gout and uric acid diathesis in doses of 4 grains. Xchthyolum Austriacum. (Petrosul- fol.) This is a product obtained by the sul- fonation of a mineral oil having a large sulfur content, neutralizing with am- monia, and purifying the product. The action and uses are claimed to be the same as are attributed to ichthyol. Ichthyomenthol. This is the name given to an alcoholic solution of ichthyol, menthol, methyl salicylate and aromatic oils. The mix- ture is recommended for the external treatment of myalgia and rheumatic pains. Idiaton. Its approximate composition is given (according to W. D.) as follows: Venice turpentine part 1 Mastic .part 1 Chloroform parts 3 Spirit of ammonia parts 2 Oil of clove parts 2 Oil of mustard (volatile), a small quantity This is a toothache remedy sold largely in Germany. Indoform. This is a white powder, obtained by the action of formaldehyde on acetyl- salicylic acid. It is sparingly soluble in cold water and has an acid, astringent taste. It is decomposed by the alkaline secretion of the intestines, forming at first methyleneglycol, which ultimately liberates formaldehyde. It has been given in gout, rheumatism, and neuralgia in the form of tablets, containing 7^ grains, one to three of which are taken in a glass of water during or after a meal. Infant Sedative Alkaline. (31) Each fluidounce is stated to contain Catnep gr. 40 Celery seed gr. 24 German chamomile gr. 24 Fennel seed gr. 24 Magnesium hydrate (in sus- pension) gr. 24 Syrup of lactucarium m. 80 772 THE STANDARD FORMULARY It is recommended as an antacid and laxative for children. Influenzine. This is stated to be a mixture of phenacetine, caffeine, sodium chlorid and quinine salicylate. Ingestol. So far as known, this contains mag- nesium, sodium and potassium sulfates, sodium and ferric chlorids, alcohol and water. — Coblentz. Ingluvin. This is stated to be an enzyme derived from the digestive apparatus of the do- mestic hen. It is in yellowish powder. It is used in dyspepsia and the morning sickness of pregnancy, in doses of 5 to 10 grains. Injectio Amylopsini (Hypodermic.) (70) This is put up in sealed ampoules. It is stated to be prepared from the pan- creas glands, and presents in a stable sterile solution, pancreatic diastase (amylopsin) devoid of the proteolytic (trypsin) and fat-splitting (lipase) fer- ments. Injection Hirsch. This is a preparation containing 1% of mercury oxycyanid and ^2% of acoin. Injectio Trypsin! (Hypodermic.) (70) This is put up in sealed ampoules. It is prepared directly from the fresh pan- creas gland. It is stated to contain tryp- sin in normal association with the other soluble enzymes and constituents of the pancreas secretions. Intestin. This is a compound or mixture of bismuth oxid, naphthalin and benzoic acid. The dose is 5 to 10 grains. Iodalbacid. This is a combination of albumin and icdin, containing 10% of the latter. It is a yellowish powder, soluble in water, and is used internally as a substitute for iodids in doses of 15 grains 3 times daily. Iodalbin. (159) This is a compound of iodin with al- bumen, containing 21^4% of iodin. It is a reddish-colored powder, practically tasteless, and of a peculiar, not unpleas- ant odor. It is insoluble in water, alco- hol or acids, but soluble in water, alcohol or acids, but soluble in alkaline solu- tions. It has the properties of other iodids. It is marketed in the form of powder or in 5-grain capsules. Iodalgine. This is an organic compound of iodin stated to contain 50% of the latter. It is said to liberate iodin on contact with the tissues and is therefore a powerful antiseptic. It is odorless and soluble in water. It is used as a substitute for iodoform. The internal dose is 6 to 8 grains. lodalia. This is a saccharated compound of iodin with tannin, which is stated to con- tain 1.2% of iodin. It is in yellow, amorphous masses soluble in water and of a sweet taste. It is an agreeable method of administering iodin to chil- dren, being said to be well borne by in- fants. The dose is 1 to 2 teaspoonfuls 3 times a day. lodamyl. This is a name for iodized starch, which see. Iodan. (69) This is stated tc be a 25% solution of iodin in goose oil from which the stearin has been removed. It is a dark brown, oily liquid. It is used externally and internally wherever iodin is indicated. It is marketed in two strengths, 10% and 25%. The former is intended for ex- ternal use, the latter for internal use, and is put up in 5 and 10-minim cap- sules. Iodferratose. (26) This is a syrupy liquid containing 3/10% each of iron and iodin. Iodia. (19) This is described as a combination of the active principles obtained from the PROPRIETARY AND SYNTHETIC REMEDIES. 773 green roots of stillingia, helonias, saxi- fraga, menispermum and aromatics, and to each dram of liquid used is said to be added 5 grains of "iod. potas." and 3 grains of "phos. iron." Iodic Acid. This is in white, rhombic crystals, which are soluble in water but insoluble in alcohol. It is put up in the form of pencils, which are used as a caustic, as- tringent and hemostatic for the removal of warts, in the treatment of chancroids, etc. Iodin-Eugenol. (Iodo-Eugenol.) This is a compound analogous to thy- mol iodid. It is a yellowish powder, in- soluble in water, slightly soluble in alco- hol, and soluble in ether and fixed oils. It is used as an antiseptic. Iodinized Emulsion. (Scott.) (58) Each fluidram is stated to contain Oil of turpentine m. s J / 2 Oil of nutmeg m . 1 Oil of wintergreen, true m. l / A Oil of peppermint m. % Carbolic acid gr. y 2 Iodin gr . y g Alcohol m . 4^ Simple syrup, Elixir of lactated pepsin, q. s. It is recommended for typhoid fever, dysentery, chronic diarrhea, etc. Iodinol. (128) This is an iodized sesame oil similar to iodipin. Iodipin. (Iodized Sesame Oil.) (130) This is an iodin addition product of sesame oil. It is prepared by action of iodin chlorid on sesame oil in sufficient quantity, theoretically calculated, to pro- duce the required iodization. It is a thick, yellow, oily liquid having a purely oily taste; it is insoluble in water and alcohol but soluble in ether and chloro- form. It is made in two strengths, 10% and 25% iodin, the former being intend- ed for internal, the latter for hypoder- mic use. The former is always supplied unless the latter is specially mentioned. The 25% is also supplied in capsules containing 30 grains each. It acts upon the system similarly to Ihe iodids, but its action is said to be more lasting and to have less tendency to iodism. The dose of the 10% is 1 to 3 fluidrams 3 times a day in emulsion or pure flavored with peppermint oil, of the 25% (hypodermically), 30 to 90 minims. Iodized Starch. This is now mentioned in the appen- dix to the N. F. It is coming into use again as a substitute for iodin and io- dids, for internal and external use. Iodlecithin. This is a compound of iodin and leci- thin, stated to contain 20% of the for- mer. It is a brownish-red substance of the consistence of lecithin. Iodoanisol. (Orthoiodoanisol.) This is an oily liquid of an aromatic, very penetrating odor, insoluble in wa- ter, very soluble in alcohol, ether and chloroform. It is said to be a powerful antiseptic. Iodocol. This is a combination of iodin and guaiacol. It is used in consumption, tuberculous bronchitis, and the catarrhal stage of bronchial asthma in doses of 3 to 6 grains 4 times a day. Iodocrol. (Carvacrol Iodid.) (Ill) This is an iodin derivative of the phenol carvacrol. It is a light, nearly odorless powder, soluble in ether, chlor- oform and oils. It is recommended as a substitute for iodoform. It is patented in the United States. Iodo-Eigon. This is an insoluble, odorless powder, containing 20% of iodin in combination. It is used as a substitute for iodoform in the treatment of wounds and sores, and is also employed in gynecological cases, such as ulcerations and catarrhal conditions. It may be mixed with oint- ments or with talcum to be used as a dusting powder. ; i THE STANDARD FORMULARY Iodo-Eigon-Sodium. This is a yellowish, odorless, almost tasteless powder, soluble in water, and containing 15% of iodin. It is intended for internal use. lodo-Eigon Wine. This contains in each teaspoonful 1 grain of iodin in combination with albu- men. Iodo-Eugenol. See Iodin-Eugenol. Iodofan. This is a condensation product of formaldehyde and iodoresorcin. It is a brick red, odorless, tasteless powder which is used as a substitute for iodo- form and thymol iodid. It contains 36% of iodin. Iodoformal. (212) One hundred grams are stated to con- tain thymol iodid equivalent to .156 grams of thymol; bismuth subiodid equivalent to 2 grams of bismuth sub- nitrate; cinchonine periodid equivalent to 4.92 grams of cinchonine sulfate ; acetanilid, 20 grams; phenyl salicylate, 1 gram ; phenol, J /2 gram ; formaldehyde- gelatin equivalent to 1.25 gram of 40% formaldehyde solution ; and boric acid, 6/-39 gram. It is said to liberate iodin, formaldehyde and phenol in contact with the tissues. Iodoformin. This is a combination of formin and iodoform, which is stated to contain 75% of iodoform which is liberated on contact with wound tissues. It is a whitish powder with a faint iodoform odor and insoluble in w r ater, alcohol or ether. Iodoformogen. (Iodoform Albumi- nate.) (109) This is a nearly odorless mixture of iodoform and albumin. It is prepared by precipitating a solution of albumin with alcoholic solution of iodoform and heating the precipitate at 120 C. It is and non-conglutinating. It is insoluble in water and sterilizable at ioo° C. with- out decomposition. Its action is that of iodoform, which is slowly liberated in connection with wound surfaces, making the action more persistent. Being about three times as voluminous as iodoform, it is usually ap- plied undiluted to the affected parts. Mixed with an equal amount of boric acid, it may be used as a snuff in ozena. Iodogallicin. (Bismuth Oxyrodo- methyl-Gallate.) This is a light amorphous grayish powder, odorless and insoluble in the or- dinary solvents. In contact with acids, alkalies or water, it is gradually decom- posed into its components. It is used on wounds and ulcers and is recommended for ulcers of the cornea. Iodoglobin. This is a name given to a kaolin poul- tice mass. Iodo-Hemol. (Iodized Hemol.) This is hemol containing 16% of iodin. It is used as an alterative instead of other iodids, the dose being 3 to 10 grains 3 times daily. Iodol. (Tetriodopyrrol.) This is a brown, inodorous, tasteless powder, insoluble in water, soluble in 3 parts of alcohol, 15 parts of ether, 50 parts of chloroform and 3 parts of oils. It contains 89% of iodin. It is used as an antiseptic instead of iodoform, hav- ing the advantage of being odorless and non-toxic. Internally it is used as ;• general alterative in doses of 5 to 10 grains. Iodo-Mangan. (Liquor Ferro-Man- gani Iodopeptonati.) This is Ferro-Mangan (which see), to which has been added 45% of iodo- peptone, the latter containing 15% of iodin. It forms a clear dark-brown li- quid of agreeable odor and taste and a slightly acid reaction. It is claimed to a very fine, voluminous, light-yellow, 1 be a reconstructive tonic of value in nearly odorless nowder, non-hygroscopic | scrofula, rheumatism, etc. PROPRIETARY AND SYNTHETIC REMEDIES. 775 Iodo-Mildine. (63) Each ounce is stated to contain Iodin (in free state) gr. 4 Oil of pine needles m. 10 Oil of cubeb m. 15 Oil of eucalyptus m. 4 Camphor gr. 4 Menthol gr. 4 Phenol m. 2 Mildoline (benzoinated), q. s. Iodo-Nucleoid. (63) This is described as a combination of iodin with nuclein, containing 23% of the former. It is said to be a tasteless, non-toxic, non-irritant substitute for po- tassium iodid and other alkaline iodids. It is a reddish-brown powder, of faint odor and taste of iodin, insoluble with usual solvents and acids but soluble in alkaline liquids. The dose is 20 grains 3 times a day, which may be increased. It is also put up in 5-grain tablets. See also Hydrag-Iodo-Nucleoid. Iodophene. This is now known as nosophene, which see. IodophenocMoral. This is a mixture of equal parts of tincture of iodin, chloral hydrate and carbolic acid. lodopyrin. (Iodantipyrin — Anti- pyrin Iodid.) This occurs as colorless crystals or white crystalline powder, readily soluble in alcohol, sparingly in water. It is used as an analgesic, antipyretic and altera- tive in tuberculosis, migraine, etc, the dose being 5 to 15 grains 3 times daily. Iodose. This is described as being a definite compound of iodin with a nucleoproteid containing 10% of the latter. It is a reddish powder, insoluble in the gastric juice but soluble in the intestinal secre- tions. It is recommended for syphilis, rheumatism, goiter, asthma, etc., in doses of 5 to 20 grains before meals. Iodosol. This is a name said to be applied sometimes to iodine vasogen. Iodosyl. (143) This is described as a definite chemi- cal compound containing 65% of iodin. It is an amorphous, bulky, garnet-col- ored powder, nearly odorless and is non- caustic, non-irritating and non-toxic. It is insoluble in water and oils and only slightly soluble in alcohol, ether or chlor- oform. It is an antiseptic and disinfect- ant, used as a dusting powder, either alone or with boric acid or talcum or in ointment form for burns, scalds, sores, chancre, ulcer, catarrh, etc. It is put up as an ointment containing 6%, also as "opthalmic ointment" con- taining 2%, also as pencils (for gonor- rhea), ovoids (vaginal), nasal points (for catarrh), suppositories (for hem- orrhoids), and gauze (moist) containing 5%. Iodothyrine. (Thyroiodin.) This is a trituration of the active prin- ciple of the thyroid gland with sugar of milk, each 1000 parts representing 1000 parts of fresh gland and containing 3 parts of iodin. The fresh glands are freed from fat and boiled with dilute sulfuric acid; the liquid is cooled, the part that separates is collected, dissolved in alcohol, and evaporated to dryness. The product is further purified by wash- ing with ether, after which it is mixed with 309 parts of milk sugar. The fin- ished product is a white or yellowish white powder of the taste of milk sugar. It is used as an alterative and discutient in goiter, corpulency, myxedema, psori- asis, menstrual disorders, etc. The dose for adults is 10 to 30 grains; for chil- dren, 5 to 15 grains, per day. It is mar- keted in the form of powder and as 5- grain tablets. Iodozen. (131) This is stated to be an iodin derivative of methyl salicylate. It is a yellowish, nearly odorless powder, insoluble in wa- ter, soluble in 2 parts of alcohol, 3 of ether and 10 of chloroform; it is said to be non-toxic and non-irritant, and does not discolor the skin. It is used as an THE STANDARD FORMULARY antiseptic, either plain or mixed with starch, boric acid or acetanilid, or in the form a 10% ointment, for sores, burns, wounds, for catarrh of the nose and other catarrhal conditions, etc. Iodyloform. This is a combination of iodin with some gelatinous substance, containing 10% of iodin. It is a yellowish brown, inodorous powder, insoluble in water, alcohol or ether. It acts as an antiseptic by the gradual liberation of iodin, and is recommended for infected wounds, ab- scesses and sores of all kinds. Iothion. (Di-Iodo-Hydroxy- Propane.) This is a yellowish, oily liquid, of sp. gr. 2.4 to 2.5, and containing jy% of iodin. It is volatile at the body tempera- ture and not unpleasantly odorous. It is insoluble in water but soluble in glyce- rin, oils, alcohol and other organic solv- ents. It is incompatible even with weak alkalies, should be kept in a cool, dry place, and be well corked. It is said to be a satisfactory substitute for iodin and iodids and is applied to the surface of the body in the same manner as mer- curial ointment ; it is said to be rapidly absorbed by the unbroken skin. It is applied generally in the form of a 2$ to 50% ointment with a mixture of equal parts of wool fat and petrolatum as the vehicle. 30 to 60 grains is applied per day. Irisol. (66) This is stated by the manufacturers to be composed of iodoform and boric acid, and is said to be odorless. It is a reddish, resinous powder, soluble in eth- er, chloroform, fats and oils. Iron Glycerophosphate. This is in yellowish scales or powder, soluble in water or diluted alcohol. It is used as a nerve tonic and reconstructive in neurasthehenia, convalescence, etc. Dose : 2 to 5 grains 3 times daily. Iron Jelloids. These are of the same composition as Bland's pills, but the mass is made up with a jujube paste to prevent deteriora- tion of the ferrous carbonate. Iron Succinate. This is an amorphous, red-brown pow- der, insoluble in water or alcohol. It is recommended as a solvent of biliary calculi. The dose is 60 grains after meals, at the some time chloroform is given in 10-drop doses 4 to 6 times daily. Iron Tonol. (178) This is a name for iron glycerophos- phate. Iron Tropon. This is a brownish powder which is an albumenoid food preparation com- posed of tropon (pure albumen) and iron in an assimilable form, and also contains cocoa. The iron content is stated to be 2 l / 2 %. It forms a soluble, palatable powder which is given in tea- spoonful doses 3 times daily with water, milk, etc., in anemia, chlorosis, convales- cence, etc. Iron Vanadinate. This is a dark grayish-brown powder, practically insoluble in water. It is used in anemia and chlorosis in doses of 1/60 grain 4 or 5 times daily every other day. Isarol. This is produced by distillation of the bituminous shale which is found in cer- tain parts of the Alps, the distillate then being sulfonated and neutralized with ammonia. It is a dark, thick liquid like ichthyol, soluble in water, and used in the same manner. Isoform Powder. This is a mixture of para-iodoxy-ani- sol with an equal weight of calcium phosphate. Para-iodoxy-anisol is pre- pared by the oxidation of iodoanisol with chlorid and hypochlorites and is a colorless powder having a slight anise- like odor. It is soluble with difficulty in water and practically insoluble in al- cohol and ether. It may be heated in the dry state to about 200 C. without decomposition. It contains over 47% ot iodin and liberates iodin from a solution PROPRIETARY AND SYNTHETIC REMEDIES. 777 of potassium iodid and acetic acid. It is liable to explode if heated or triturated, hence it is marketed in a mixture with an equal weight of calcium phosphate, which is designated "isoform powder." It is incompatible with acids and with reducing agents, such as iodids and with the substances generally which are in- compatible with iodids. It is a germicide and antiseptic in consequence of its oxidizing power, and is recommended as a substitute for iodo- form. It is claimed to be non-toxic in comparatively large doses. The dose in- ternally is 10 to 30 grains per day. Ex- ternally it is used as a dusting powder, as a paste with glycerin, in ointments, gauzes, etc., up to 10% of pure isoform. The manufacturers supply an isoform paste, consisting of equal parts of pure isoform and glycerin, and isoform gauze. Isonaphthol. This is another name for betanaph- thol. Isophysostigmine. This is an alkaloid prepared from the ether-insoluble portion of the extract of calabar bean. The alkaloid is chemical- ly similar to physostigmine, but physio- logically it is about Yz stronger. Isopral. (Trichlor-Isoproyl Alcohol.) This is obtained by reacting, on chloral with magnesium-methyl iodid and de- composing the compound formed. It is in prismatic crystals of a camphoraceous odor and an aromatic, somewhat pun- gent taste. It volatilizes very readily at the ordinary temperature, forming sub- limates similar to camphor. It is soluble in 35 parts of water but more freely in alcohol or ether. It should not be ex- posed to heat or air. Its action resembles that of chloral but is active in smaller doses, being about twice as strong. It may be used as a substitute for chloral, and is ser- viceable as an alternative in cases in which it is necessary to give hypnotics a long time. The dose is 5, 10 or 15 grains in capsules or wafers, which should be dispensed in a well-stoppered bottle. Itrol-Crede. This is a silver citrate which is in a very fine powder and is used for dis- eases of the eye. Owing to the fact that it is extremely sensitive to light and air, it is put up in small black bottles con- taining ^ or 1 gram each. See also Antiseptic-Crede. Izal, Medical. This is an English preparation which is in the form of an emulsion containing 40% of "izal oil." This is described as a new coal product which is recommend- ed as an antiseptic and germicide for in- ternal and external use. Medical izal is used internally in typhoid fever, dysen- tery, etc., in doses of 5 to 10 drops. Izal is also put up in the form of gauze, lozenges, ointment, soap, etc. Janeway's Pills. These are recognized in the N. F. un- der the title Compound Pills of Aloes and Podophyllum, the formula being as follows : Each pill is to contain Aloes gr. 1 Resin of podophyllum gr. Yz Extract belladonna leaves gr. Ya Extract of nux vomica gr. % Jecorin. (Matterer's Cod Liver Oil Tablets.) Each tablet is stated to contain Cod-liver oil gr. 45 Malt extract, dried gr. 15 Cocoa gr. 15 Sugar gr. 75 Together with glycerin, vanillin, oil of bitter almonds (free from acid) and Ceylon cinnamon oil. Jecorol. This is another name applied to the extract of cod-liver oil (see Gaduol and Morrhuol). It is also applied to a Swiss preparation which is an emulsion of cod-liver oil containing chocolate and other flavors. This latter is put up in combinations : THE STANDARD FORMULARY Jccorol guaiacolate. containing 2% of | Kahama Urethral Bougies. (102) guaiacol carbonate. Jecorol iodid, containing 10% of iodi- pin. Jccorol lecithinate. containing .6% of lecithin. Jequiritol. This is a sterile solution of abrin, the active principle of Abrus precatorius, and is used in ophthalmic practice. It retains its activity unimpaired. It is marketed in four strengths. Jesson's Dental Anaesthetic. This contains about 2.6% of cocaine hydrochlorid with some carbolic acid and oil of rose. — Sadtler. Jewsbury & Brown's Oriental Tooth Paste. The following makes, according to Nelson's "Handbook," a similar prepara- tion : Carmine gr. 60 Water fl.dr. 2 Honey av.oz. 6 Oil of peppermint drops 5 Oil of anise drops 5 Oil of orange drops 10 Oil of wintergreen drops 10 Precipitated chalk sufficient Rub together, using enough precipi- tated chalk to make a firm paste. Jim Crow Corn Salve. The principal active ingredient is stat- ed to be salicylic acid, according to the manufacturers. Judkins' Ointment. Linseed oil av.lb. 1 Red lead av.oz. 4 Lead acetate gr. 60 Oil of turpentine m. 30 Boil the oil in an earthen pot, add the red lead, gradually and with stirring, and then incorporate the other ingredi- ents.— D. C. Joret & Homolle's Apiol Capsules. According to Hager, these contain 3 grains of apiol each. Kadiol. This is a name said to be applied to oil of cade. The formula is given as follows by the manufacturers : Hydrastin muriate gr. 1/60 Soda benzoborate gr. \V\ Concentrated thymic sol m. 2^4 Zinc sulfocarbolate gr. 34 Oil of cassia m. 1/16 Boroglyceride solution m. 6*4 Gelatin, glycerin, q. s. Kaiser Pillen. (Pilulae Imperiales.) Various formulas are used for these, the most common one being Resin of jalap gr. 30 Resin of scammony gr. 30 Gamboge gr. 30 Aloes gr. 30 Extract of colocynth gr. 6 Soap gr. 15 Gentian root gr. 38 Water, to make 100 pills. Sometimes calomel is added. — Hager. Kalendol. (148) This is stated to contain no grains of acetanilid per ounce, also calendula, ichthyol, boric acid, and "imicition" a coal tar product with an iodin base. Kali-Caffeine. (181) This is a granular effervescent prep- aration described as containing in each dose of a heaping dessertspoonful 1 grain of caffeine bromid, 2 grains of po- tassium and sodium bromids with pure magnesium citrate. Kalydor. Bitter almonds, blanched, .av.oz. 10 Rose water fl.oz. 50 Corrosive sublimate gr. 5 Ammonium chlorid av.oz. Y\ Cherry laurel water fl.oz. 1Y2 Alcohol fl.oz. i l / 2 Mix an emulsion of the almonds and the rose water, strain, add the ammon- ium chlorid and cherry laurel water, and then the corrosive sublimate dis- solve in the alcohol. — Nat. Dr. Kasagra. (Flext. Case. Sag. Aromat. Stearns.) (187) This is described as a fluid extract of prime cascara sagrada, aromatized and sweetened. It is made by a special process. The product is stated to con- PROPRIETARY AND SYNTHETIC REMEDIES. 779 tain about 2% of alcohol. It is recom- mended as a palatable preparation of cascara, owing its laxative effects to this drug alone. Kastanol. This is Fliegge's extract of horse chestnut, i. e., the active principle of horse chestnut, with about 8% of cam- phor. The preparation is made by a patented process, has some analgesic ef- fect, and is to be employed by friction and painting in rheumatism, gout sciat- ica, and other chronic muscular pains, frost bites on the hands and feet, etc. Kasucolum. This is a name for potassium guaiacol sulfonate, also known as thiocol. Katharol. This is stated to be a solution of hydrogen peroxid. Keating's Cough Lozenges. These are said to be composed of Lactucarium dr. 2 Ipecac dr. 1 Squill gr. 45 Extract of licorice av.oz. 2 Sugar av.oz. 6 Mucilage of tragacanth to^make a mass Make into 20-grain lozenges. — Cooley. Keimol. (Liq. Keimol.) (106) This is described as being prepared from phenyl salicylate and the active constituents of Thymus vulgaris, Gaul- theria procumbens, and Mentha piperita. Kelene. (77) This is ethyl chlorid put up in special tubes, called "autospray," and intended for producing local anesthesia. The ethyl chlorid is also put up in these tubes in combination with cocaine, ichthyol, iodin, iodoform, menthol, resorcin, mer- curic chlorid, formaldehyde, etc. Kenyon's Antiseptic Powder Comp. See Antiseptic Comp. Powder. Kephalgine. This consists, according to the Amer- ican Journal of Pharmacy, of Antipyrin parts 5 Roasted coffee parts. 5 Caffeine parts 2 Sodium salicylate parts 2 Kephalopin. This is an oily extract, prepared by cold process of the fresh nerve tissue of the brain. It is non-toxic and may be exhibited hypodermically. It is em- ployed in nervous disorders, St. Vitus dance and epilepsy in doses of 5 cc. Kepler Solution. (32) This is described as a mixture of cod liver oil with Kepler malt extract. It is also put up in combination with hemog- lobin, iron iodid, hypophosphites, pan- creatin and phosphates. Kern's Insect Annihilator. The following is said to resemble' this mixture (W. D.) : Deodorized benzin fl.oz. 16 Oil of cedar fl.oz. 1 Oil of wintergreen fl.oz. I This composition is said to be cer- tain destruction to cockroaches, bedbugs, fleas, ants, and other insects. Kestin. (10) This is stated to contain trinitrophenol, resorcin, ammonium chlorid, formalde- hyde and orthoboric acid. It is used internally and externally. Kickapoo Indian Oil. This is stated to contain camphor, capsicum, gum myrrh, opium, oils of clove and sassafras, ether, alcohol and water. Of the alcohol it contains 60%,, of the ether, 8 minims to each fluid- ounce, and of the opium, 11/20 grain to each fluidounce. Kineurin. This is a name for quinine glycero- phosphate. King's Dandelion and Quinine Bilious and Liver Pills. These contain rhubarb, aloes and bitter aromatic extracts.— Geissler's analysis in H. KinsePs Tasteless Cod-Liver Oil Compound. (93) This is stated to contain cod liver oil, extract of malt, compound syrup of hypophosphites and wild cherry. rso THE STANDARD FORMULARY King's Royal Germeteur. According to Slack's analysis, this was found to consist approximately of Saturated aqueous solution of sulfuretted hydrogen fl.oz. i Sulfuric acid fl.oz. 2 Well or river water gall. 1 Mix the acid with the water and add the sulfurretted hydrogen solution. Klyne's Nerve Restorer. The following is said to make a sim- ilar preparation (Dr. R. C. McCann) : Ammonium bromid gr. 180 Potassium bromid av.oz. 3 Potassium bicarbonate gr. 70 Tincture of columbo fl.dr. 6 Water fl.oz. 6 — N. I. Knight's Pills. These are made from 6 parts of aloes, 3 of scammony and 1 of gamboge. Each pill weighs 4 grains. — H. Koenig's Hamburg Breast Tea. This is a mixture of licorice root, marshmallow root, red poppy flowers, mallow flowers, althea leaves, and the yellow flower of a stellaria. — H. Kola-Steams. (187) Each fluidounce is stated to represent one troy ounce of fresh kola nut, being a specially aromatized fluid extract. It is used for the same purposes as kola nut and caffeine, the dose being V* to 1 teaspoonful 3 times a day. Kola Digestive Tablets. (171) These are stated to contain kola, so- dium bicarbonate, pepsin and nux vomica. Kola-Koloid. (132) This is stated to be "a pure wine of kola and coca combined." Kolaton. (171) This is stated to contain kola, cocoa, celery, "iodated" with burgundy wine. Kondon's Catarrh Jelly. On the package it is stated that this is composed of the following drugs only : Petrolatum, cocoa butter, menthol, oil peppermint, oil eucalyptus, oil lavender flowers, phenol. Korpulin. This is stated to contain the extracts of Fucus vesiculosus, Tamarindus indi- cus and Cascara sagrada. It is employed as an anti-fat preparation. Koryl. This is described as a compound of "orthophenol-sulphonborosalicylic acid with iodomenthol, i%." It is a white powder reputed to be an antiseptic. Koussein. (Brayerin.) This is a yellowish-brown powder, soluble in alcohol, ether or chloroform, sparingly in water. It is used as an anthelmintic in doses of 15 to 30 grains, divided into 3 or 4 doses, given in powders or in oills, at intervals of half an hour, followed by castor oil. Kresamine. (Trikresolamine.) (178) This is an aqueous solution of 25% each of trikresol and ethylene-diamine. It is a clear, colorless liquid, miscible in all proportions with glycerin and sol- uble in about 4 parts o f water, but insol- uble in petrolatum. It is claimed to be a powerful bactericide with a minimum of toxicity. It is said to have great powers of tissue penetration and to act sedatively to inflamed tissues. It is recommended for the treatment of ul- cers, eczema, lupus, and other skin af- fections in the form of solutions con- tained 2 to 25 parts of water; it may also be used in the form of oint- ment. Kreso. (159) This is a coal-tar product composed largely of cresols and the higher phen- ols. It is a dark brown, alkaline liquid, mixing readily with alcohol, chloroform or ether, but forming a whitish, emul- sion-like liquid with water. It is a powerful antiseptic and is used, diluted with water, for disinfecting sick rooms, urinals, etc., it is recommended as a dressing for wounds, etc., on animals, and also as a parasiticide. Kryofln. (Methoxy-Acetphenetidin.) This is in white, odorless, tasteless crystals, soluble in 52 parts of boiling PROPRIETARY AND SYNTHETIC REMEDIES. 781 water and 600 parts of cold water, freely soluble in alcohol, ether or fixed oils. It is recommended as an analgesic and antipyretic in doses of 4 to 8 grains. Kugloids. These are capsules containing glycero- phosphate of quinine, eucalyptol and benzoate of creosote. They are im- ported from France. Kumysgen. (167) This is a preparation of powdered milk, used as a dietetic in convalescence and various diseases. Kurin. This is a mixture of compound lic- orice powder and phenolphthalein put up in tablet form. Lac Bismo. (91) This is a mixture said to consist of bismuth hydrate and subcarbonate, sus- pended in water, in a finely divided state, and containing 2 x / 2 grains of the com- pounds in each fluidram. It is used as an antacid in doses of 1 to 4 teaspoon- fuls. Lac Bismuthi cum Pepsino. (142) Each fluidounce is stated to contain Bismuth citrate (amorphous hydrate) gr. 16 Pepsin U. S. P. (as glycerole) gr. 16 With_ hydrochloric and lactic acids. Lactated Pepsin. Pepsin av.oz. 1 Pancreatin av.oz. 24 Diastase gr. 28 Hydrochloric acid m. 40 Lactic acid m. 40 Milk sugar av.oz. 5 Lactagol. This is stated to be a dry extract of cottonseed which has been recommended as a galactagogue. It is yellowish, fine, light, inodorous powder, not soluble in water but readily mixing therewith. Lactenzyme Elixir. See Elixir Lactenzyme. Lactenzyme Powder. (63) This is stated to contain pepsin, pan- creatin, ptyalin, diastase, lactic and hy- drochloric acids, and milk sugar. It is also put up in the form of 5-grain tab- lets. Lactocresol. (15) This is a dark, syrup liquid which becomes milky with water. It is a dis- infectant derived from coal-tar, and is recommended for general sanitation and disinfection. Lactol. (Lactonaphthol.) This is a compound similar to ben- zonaphthol. It is a colorless, tasteless powder. In the system it is decomposed into lactic acid and betanaphthol, hence is used as an intestinal antiseptic in doses of 4 to 8 grains. Lactone. (Buttermilk Tablets.) (159) These tablets represent, in compressed form, a pure culture of lactic acid ba- cilli, which, when added to pure milk, makes a preparation like buttermilk but containing all the butter fat. Lactopeptine. (145) This is stated to contain pepsin, vege- table ptyalin, pancreatin, and lactic and hydrochloric acids. It is also put up in the form of tablets and various combina- tions with elixirs. See Elixir of Lacto- peptine, etc., also Liquid Lactopeptine. Lactophenin. (Lactylphenetidin.) This differs from phenacetin in that the acetic acid group is replaced by the lactic acid group. It is in small, colorless crystals or white powder, odor- less and slightly bitter, and soluble in 330 parts of cold water, 56 of boiling water, Sy 2 of alcohol, and slightly solu- ble in ether. Its incompatibilities are the same as phenacetin. It is used for the same purposes as the latter, viz., as an antipyretic and analgesic in doses of 8 to 15 grains. Lactoserve. (26) This is a nutritive preparation for children made by souring pasteurized milk with lactic acid bacteria, evaporat- ing to dryness, and mixing with sugar, flour and vegetable albumin. Mixed with water it forms an emulsion re- sembling buttermilk. '82 THE STANDARD FORMULARY Lacto-Somatose. (Tannin Milk Al- bumose.) This consists of casein albumose in organic combination with 5% of tannic acid. It is an odorless and almost taste- less yellowish powder, readily soluble in water and aqueous liquids. It is use- ful as a nutritive in diarrheas, inasmuch as it nourishes the system and at the same time acts as a mild astringent to the inflamed mucous surfaces. Laird's Bloom of Youth. This is stated to contain according to one analyst, 169 grains of zinc oxid to the fluidounce, no lead being present. According to another, it contains 32% of zinc oxid. According to another analyst it contains zinc oxid and precipi- tated chalk in perfumed water. La-Kama. This is a remedy for worms in chil- dren and adults which is put up in cap- sules in two forms — Weak, each con- taining 1% g. of kamala and 1/10 g. of solid extract of pomegranate root bark; and strong, each containing i l / 2 g. of kamala and 1/10 g. of solid extract of pomegranate root bark. Lamaroux's Pectoral Syrup. According to Dorvault (in Hager), this is made from Calf's lung 1 Red poppy flowers g. 300 Iceland moss g. 300 Jujubes g. 300 Dates g. 300 Licorice g. 300 Mallow flowers g. 200 Althea flowers g. 200 Violet flowers g. 200 Lungmoss g. 100 Extract of opium g. 2.4 Sugar g. 18000 Each no g. is stated to contain 1 centigram of opium extract. Laminoids, Blaud's. (179) Each tablet contains iron sulfate and sodium bicarbonate in quantities equival- ent to Blaud's pills, but the two salts are separated into two layers so that the formation of ferrous carbonate will occur only when the tablets are moist- ened, as when they are swallowed. An excess of bicarbonate is present to neu- tralize the acid in the stomach. They are made in two sizes, 5-grain and 3- grain. They are used in the same way and for the same purposes as Blaud's pills. Langell's Asthma Remedy. According to Hager this is composed of coarsely powdered belladonna leaves, moistened with 10% solution of potas- sium nitrate, and dried. Lanichol. A purified wool fat not differing es- sentially from adeps lanae. — Coblentz. Lanesin. This is said to be mainly an ointment of wool fat with aluminum acetate and is recommended for insect bites, to pre- vent the swelling and relieve the itch- ing. Lanum. (130) This is a brand name for a purified hydrous wool- fat. Lapactic Pills. (182. a) These contain each Aloin gr. *4 Extract of belladonna gr. % Ipecac gr. 1/16 Strychnine gr. 1/60 Largin. (Silver Protalbin.) " This is a proteid-silver combination containing 11% of silver. It is a gray powder soluble in 10 parts of water, also soluble in glycerin, insoluble in alcohol or ether. It is a bactericide and astringent, used chiefly as an injection for gonorrhea in the form of Y\ to i l /i% solutions. Internally it is sometimes given in doses of 5 to 8 grains. The solu- tion should be dispensed in amber bot- tles. Laroche's Quina. See Quina-Laroche. Laroze's Syrup of Orange Peel. According to Hager, this is made from 15 parts of tincture of orange peel and 85 parts of simple syrup. PROPRIETARY AND SYNTHETIC REMEDIES. 783 Lartigue's Gout Pills. According to Wittstein, these weigh ?J4 grains and consist of 4 parts of powdered colchicum root and 1 of sugar besides the mucilaginous excipient. According to Bouchardat, they are replaceable by pills made from the fol- lowing : Comp. ext. colocynth parts 20 Extract of colchicum parts 20 Extract of . opium part 1 I-aville's Anti-Gout Liquor. According to Hager, these contain Calcium chlorid g. 5 Chinoidin g. 5 Extract of colocynth g. 2.5 Water g. 85 Alcohol g. 100 Spanish wine g. 800 These are to be taken during the acute stage. Laville's Preventative Pills. According to Hager these are made from Ext. of winter cherry berries.. g. 15 Solution of sodium silicate g. 5 Sugar and powdered marsh- mallow root, each sufficient Divide into pills weighing 0.25 g. The above-mentioned extract is to be made from the berries by removing the seeds, kneading the berries with lime water and then extracting with alcohol. Lavoline. 196) This is described as a colorless, odor- less and tasteless fluid petrolatum. Lavoris. (114) This is stated to contain zinc chlorid, cassia zeylanicum, formaldehyde, men- thol, etc. It is an astringent and anti- septic used mostly by dentists. Laxagrada. (89) This is described as "bitterless cas- cara, a concentrated extract of selected bark." Laxatina. (131) This is described as a liquid laxative, each fluidram of which contains the ac- tive medicinal properties of 15 grains each of Alexandria senna and cascara bark, freed from their irritating and other objectionable constituents. Laxan. These are tablets containing 1/10 g. of phenolphthalein, coated with choco- late. Laxative Cordial. See Red Clover Compound. Laxatol. This is a name adopted for designat- ing aromatic laxative tablets containing phenolphthalein. They are supplied in three strengths. Laxinconfect. This is the name applied to a com- pound of apple pulp and phenolphtha- lein. The dose is 1 to 3 grains. Laxol. This is described as pure castor oil, sweetened and flavored. Lebei's Scordium Pills. No. I. Extract of germander g. 1 Extract of water germander g. I Extract of yarrow .g. I Water germander (scordium) powder g. 2 Divide into 25 pills. — H. No. II have the same constitution but are exactly K larger. They are used for piles, 3 or 4 pills being given 3 times a day. Lebeuf's Coal Tar. Coal tar part 1 Tincture of soap bark parts 2 Digest and filter. — H. Lecin. This is described as an iron albumin- ate compound which is said to contain in each liter 200 g. of egg albumin, 5 to 6 g. of iron in chemical combination, 80 g. of sugar, and 150 g. of alcohol, together with flavoring essences. Lecithin. This consists of oleic, stearic, palmitic, or other fatty acids with glycerophos- phoric acid combined with cholin. It contains a greater proportion of phos- phorus than any other nerve constituent. It occurs in combination with proteids in many animal and vegetable tissues, especially in nervous matter and egg- 84 THE STANDARD FORMULARY yolk. It is best prepared from egg- yolk (in which it exists as vitellin) by dissolving out the lecithin with strong alcohol. It is a yellowish-brown, waxy solid, of peculiar odor, soluble in an equal volume of cold, abso- lute alcohol, readily soluble in chloro- form, benzin, and fats, less readily in ether. It is insoluble in water but swells and decomposes on prolonged contact. It is hygroscopic on exposure to the air. It is incompatible with alkalies and should be kept in well-stoppered bottles protected from light. It acts as a stimulant to nutrition and not as a direct nutrient. The number of red corpuscles and the amount of hemoglobin are increased, and the appe- tite is improved. Even in large doses it is not toxic. The ordinary diet con- tain I to 4 drams and some observers claim that the benefits of lecithin may be obtained by increased consumption of lecithin-containing foods (e. g. eggs). Lecithin is recommended for cases of faulty nutrition and is especially rec- ommended as an addition to cow's milk for artificially fed infants. It may be given by mouth in doses of i l / 2 to 8 grains per day, in pill form, before meals, or hypodermically 15 minims of a 5% solution in oil, daily. Infants are to receive one-third 0$. these doses. Lecithine Clin. This is described as "phosphorus in the state of an organic natural com- pound," also as "natural lecithin ex- tracted from the yolk of egg." It is put up in three forms: (1) Pills Clin, each one containing 5 eg. of lecithin ; (2) Granulated Clin, each teaspoonful representing 5 eg. of lecithin; and (3) Solution Clin, which is sold in boxes of eight sterilized tubes of 1 cc. each, rep- resenting 5 eg. of lecithin. The last is for hypodermic use, an intramuscular injection of this oily solution being ad- ministered every 2 days. Lecithine, Gare's. See Gare's Lecithine. Lecithin Glycerole. Lecithin Solution. (70) Each of these preparations is stated to contain 1 grain of pure lecithin to the fluidram. The menstruum in the former preparation is glycerin. Lecithmedullin. This is a lecithin preparation made from bone marrow. It has been rec- ommended for cardiac disorders. Lecithol. (14) This is described as an emulsion of lecithin, each dram of which contains 1 grain of pure lecithin. Lecitogen. This is a combination of lecithin with cocoa, in the form of powder, contain- ing 0.94% of lecithin. Lehrer's Croup Powder. Copper sulfate. Sugar each, equal parts. A few grains of this powder are to be blown on the diseased surface. Leinol. (Emul. 01. Lini Co.) (148) This is described as a modified for- mula of Dr. Thomson's, and is stated to contain in each fluidounce : 01. lini, 33 J A7c. Acid hydrocyani, drops 4. ■ Sulph. codeine, gr. ^2. Ol. cinnamon. Chrondrus, q. s. Lemke's Electric Liniment. This is stated to contain 62% of alco- hol, and 3 minims of chloroform, 8 of ether and 1 grain of opium to the fluid- ounce. Lenicet. This is an anhydrous basic aluminum acetate. It is a fine, white voluminous powder, insoluble in water. It is used for hyperidrosis, mixed with talcum, or in ointment or paste form for treating wounds or ulcers, the dilution being 10 to 15%. Lenigallol. (Pyrogallol Triacetate.) (109) This is triacetylpyragallol obtained by replacing the 1 ydroxyl groups with acetyl groups. It is a white crystalline PROPRIETARY AND SYNTHETIC REMEDIES. 785 powder, insoluble in water but soluble with decomposition in warm aqueous al- kaline solutions. It is said to be non- poisonous and non-irritating but a mild and painless corrosive. It was intro- duced as a substitute for pyrogallic acid in psoriasis, lupus, eczemas, etc. It is used in the form of a 5 to 10% ointment or paste in conjunction with zincoxid. Lenirobin. (Chrysarobin Tetrace- tate.) (109) This is a powder insoluble in water but soluble in chloroform. It is used like chrysahobin and for the same pur- poses, and is said to be non-poisonous, ncn-irritating and non-staining. Lentin. (130) This is metaphenylendiamine hydro- chlorid, recommended for diarrhea in children. Leontin. See Lloyd's Leontin. Lepine. An antiseptic solution said to contain Mercuric chlorid part I Bromin parts io Benzoic acid parts 50 Carbolic acid parts 100 Salicylic acid parts 100 Calcium chlorid parts 50 Quinine hydrobromid parts 200 Chloroform parts 200 Distilled water partsioo,ooo — Coblentz. Lepine's Granules Hydrocotyle Asiatica. Extract of Indian pennywort (Hydrocotyle Asiatica) g. 5 Althea root g. 2 Starch g. 2 Divide into 100 pills. — H. The extract is prepared by extracting the entire plant with 45% alcohol. Lepine's Syrup Hydrocotyle Asiatica. Extract of Indian pennywort (Hydrocotyle Asiatica) g. 1 Simple syrup g. 500 Dissolve the extract in the syrup. — H. Leprine or Leprotine. This is an antitoxin prepared from the lepra bacillus which is used in the treatment of leprosy by subcutaneous in jection in doses of 10 cc. Lera's Solution Pyrophos. Iron and Soda. According to Hager this is prepared frcm 10 to 12 g. of crystallized sodium pyrophosphate, 16 g. solution of ferrous sulfate of sp. gr. 1.317, and distilled water to make 1,000 g. Letalbin. (Lecithin Albuminate.) This is a compound of lecithin and albumin. It is a yellow powder con- taining 20% of lecithin. It is prescribed as a tonic like lecithin and glycerophos- phates. The dose is 5 to 10 grains three times a day. Leucogon Tablets. (160) These are stated to contain sodium borate, ammonium chlorid, zinc sulfate, resorcin, tannic acid, ichthyol, eucalyptol, and hydrastine (white alkaloid). They are intended for use as vaginal supposi- tories. They are made round, weighing 30 grains each, pear-shaped, weighing 30 grains, and also round, weighing 15 grains. Levulose. See Diabetin. Levurargyre. This is a mercury nucleinate intro- duced from- a French source. Lianthral. (Extr. Olei Lianthracis.) This is stated to be an extract of coal tar, which is used in various skin af- fections. Libradol. (118) This is in the form of an ointment or paste which is stated to contain "dracon- tium, sanguinaria, cephaelis, melaleuca, lobelia, laurus, capsicum, tobacco — l /i grain alkaloids to ounce." It is recom- mended as an external remedy for colds, croup, acute inflammation of the lungs or soreness depending on congestion, for sore muscles and joints, etc. Libradol, Mild is a milder form of the above which is intended for use on children. Lignol. (81) This is described as an oil distillate of lignite. It is recommended as an 786 THE STANDARD FORMULARY antiseptic and germicide for various skin diseases, wounds and ulcers. It is also put up in the form of an ointment con- taining 20% of lignol, and as a soap containing 5%. Lincoln's Hop and Celery Nerve Tab- lets. These are stated to contain fluid ex- tracts of lupulin, celery seed, cannabis indica, and capsicum. Linogen. This is a preparation recommended by Mindes, there being two forms, liquid and semi-solid. The former is made from Linseed oil g- 35 Olein, white g. 35 Spirit of ammonia g. 20 Alcohol g. 8 Ether g. 2 This is made up also in combinations with iodin (6% and 10%), morphine, peru balsam, resorcin, veratrine, iodol, mercury, chloral hydrate, etc. The semi- solid form is made from Linseed oil g. 36 Paraffin g. 24 Olein, white g. 30 Spirit of ammonia g. 10 This forms a light yellow, soft oint- ment which is capable of absorbing sev- eral times its weight of water. Linonine. (Emulsio Lini Comp.) This is stated to be an emulsion of linseed oil combined with iron hypophos- phite, marshmallow, dilute hydrocyanic acid, chondrus, glycerin, and oils of eucalyptus and wintergreen. Lipiodol. This is the same as lipobromol (which see), but contains 40% of iodin. Lipobromol. This is a brominated oil intended as a substitute for bromid salts. It is a transparent, yellowish liquid of a slight odor of poppy oil from which it is prepared and containing 2>2> l A% of bromin. It is given per mouth and sub- cutaneously, the dose being 15 to 60 grains. Liquid Cathartic. (36) This is stated to combine pure sodium sulfate with the active principles of Alexandria senna. Liquid Febrisol. See Febrisol Liquid. Liquid Haemoferrum. See Haemoferrum. Liquid Hypophosphites Lime and Soda. (137) This is stated to contain in each tea- spoonful 2 grains each of the hypo- phosphites of lime and soda. Liq. Hypophosphitum, Schlotter- beck's. See Solution of Hypophosphites. Liquid Lactopeptine. Each fluidounce is stated to represent 38 grains of lactopeptine (which see), in a glycerin menstruum with alcohol, 3%. Liquid Peptonoids. (13) This is stated by the manufacturers to contain Proteids (peptones and propeptones) 5.25% Lactose and dextrose 11.3 % Cane sugar 2.5 % Mineral constituents (ash)... 0.95% Alcohol (by volume) 17.5 % Liquid Peptonoids with Cascara. See Cascara Peptonoids. Liquid Peptonoids with Coca. Each fluidounce is stated to represent Coca leaves gr. 10 Proteids (peptones and propeptones) 5.25% Lactose and dextrose 11.3 % Cane sugar 2.5 % Mineral constituents (ash)... 0.95% Alcohol 16.5 % Liquid Peptonoids with Creosote. Each tablespoonful is stated to repre- sent Beechwood creosote m. 2 Guaiacol m. 1 Proteids (peptones and propeptones) 5.25% Lactose and dextrose 11.3 % Cane sugar 2.5 % Mineral constituents (ash) . . . 0.95% Alcohol 12 % PROPRIETARY AND SYNTHETIC REMEDIES. 787 Liquid Somatose. This is a preparation of somatose, which see. It is put up in two forms, sweetened and unsweetened. The for- mer has a mild aromatic taste, the latter is preferred when the use of sugar is objectionable. The dose for adults is i dessertspoonful to a tablespoonful, children, I to 2 teaspoonfuls, according to age. Liquid Taka-Diastase. (159) Each fluidounce is stated to contain 20 grains of taka-diastase. Liquocide. This is a new name for Liquozone, which see. Liquor Ambrosia (Curtis.) (76) Each fluidram is stated to contain 5 minims of the fluid extract of the leaves of Ambrosia artemisiaefolia. It is rec- ommended for hay fever. Liquor Antisepticus, Volkmann's. A solution supposed to contain alco- hol, part i; water, parts io; and gly- cerin, parts 20. — Coblentz. Liquor Aromaticus. This is said to be a mixture of oils of lavender, clove, cinnamon, thyme, lemon, mace, and bergamot with alco- hol. Liquor Diastos. (141) Each fluidounce is stated to contain Pepsin (i 13000) gr. 4 Papain gr. 1.36 Rennin gr. 0.68 Diatase gr. 0.09 Pancreatin gr. 0.23 Nitrohydrochloric acid, dil m. 5 Lactic acid m. 0.5 Nux vomica gr. 0.45 Liquor Ferri-Mangan. (141) This is stated to contain 0.6% of iron in the form of peptonate and 0.1% of manganese. Elsewhere it is also stated that each fluidounce contains 20 grains of iron peptonate and 4 grains of man- ganese sesquioxid . Liquor Ferri-Mangan Comp. This is stated to contain 0.6% of iron, 0.1%. of manganese, and 1/64 grain of 50 strychnine sulfate and 1/16 grain of strontium arsenite. Liquor Ferri Mangan Comp. with Cas- cara is the same as the above but rep- resents in addition 40 grains of cascara sagrada to the fluidounce. Liquor Ferro-Mangan Aromaticus. (Urban) (Aromatic Elixir Pepto- nate of Iron and Manganese.) (Ill) This is described as a neutral pepton- ized solution of iron, 0.42%, and man- ganese, 0.07%, combined with aromatics. Liquor Ferro-Mangani Brompepto- nati "Dieterich." See Bromo-Mangan. Liquor Ferro-Mangani Peptonati "Dieterich." See Ferro-Mangan Dieterich. Liquor Hepatica. (31) Each fluidounce is stated to contain 5 drams of sodium phosphate, 48 minims of tincture of iron chlorid, and aro- matics. Liquor Lappce Comp. (160) Each fluidounce is stated to contain Detan. solution calisaya m. 350 Detan. burdock root m. 50 Detan. elixir cascara m. 50 Arsenic iodid gr. 1/50 Combined iodids gr. 7^ The latter consist of the iodids of po- tassium, sodium, ammonium, calcium, manganese and iron. Liquor Pancreaticus. (132) This is described as an active solution of the digestive ferments of the fresh pancreas. Liquor Sedans. (159) Each fluidounce is stated to represent Black haw gr. 60 Hydrastis (represented by the white alkaloid) gr. 60 Jamaica dogwood gr. 30 Aromatics. It is recommended as a utero-ovarian sedative and anodyne. Liquor Sedans with Cascara. This is similar to the preceding but contains in addition 40 grains of cas- cara sagrada to the fluidounce. THE STANDARD FORMULARY Liquor Tritici. (Liquor Tritici Con- centratus.) (159) This is described as a solution of which each 15 minims represents 27 grains of couch grass in a menstruum containing 23^% of alcohol. It is made by exhausting the drug with water con- centrating the percolate in vacuo, and preserving the product by the addition of 23H% of alcohol. It is used as a diuretic in doses of 1 to 4 fluidrams given every 2 to 4 hours. Liquor Uterans. (207) According to the manufacturers, each fluidounce represents Black haw gr. 55 Blue colosh gr. 28 Jamaica dogwood gr. 25 Hydrastis (represented by the white alkaloid) gr. 55 Aromatics. Liquozone. According to Dr. Kebler, this- con- sists virtually of a solution of sulfur dioxid in water. Other chemists seem to confirm this analysis. Listerine. (113) This is described as "the essential an- tiseptic constituent of f hyme, eucalyptus, baptisia, gaultheria and mentha arvensis, of each, 1 part ; especially prepared bor- acic acid, 29 parts ; benzoic acid, 1 part ; rectified spirits, 250 parts ; water to make, 1,000 parts. " Lithiated Hydrangea Comp. (113) This is stated to represent the active properties of fresh Hydrangea arbore- scens, Berberis aquifolium, and Scroph- ularia nodosa, together with benzoate and salicylate of lithia. Lithiated Sorghum Comp. (182a) Each fluidounce is stated to contain 120 grains of a combination of broom- corn seed, corn silk, saw palmetto, and hydrangea, together with 16 grains of lithium benzoate and citrate. Lithium Arrhenal. This compound is analogous to the sodium compound which is described under Arrhenal, which see. It is in deli- quescent crystals which are soluble in water. The dose is 1 to 3 grains twice daily. Lithium Ichthyol. This is a lithium derivative of ichthyol. It is a dark brown mass quite similar to ammonium ichthyol in appearance but is more dense. It is an antiseptic and bactericide, and is recommended as an antiseptic application for wounds and in syphilis. Lithium Tonol. (178) This is a name given to lithium gly- cerophosphate. Litholine. This is petrolatum or petroleum jelly. Lithona. (181) This is described as a combination of salts of lithia with mild saline laxa- tives. Lithos. (141) This consists of effervescent tablets of lithium and sodium salicylates, each con- taining y 2 grain of the latter. It is also put up without the salicylate. Lithyol. This is a preparation somewhat simi- lar to ichthyol. Lloyd's Hydrastis. This is described as a hydrastis prep- aration from which is excluded the col- oring matters of the drug and other un- desirable constituents. Lloyd's Leontin. This is a 1% solution of leontin, ac- cording to the manufacturers' statement, leontin being the active emmenagogue principle of Caulophyllum thalictroides. Sugar gr. 120 Starch gr. 120 Acacia gr. 60 Lactucarium gr. 15 Also mix equal parts of vinegar and oxymel of squills and wine of ipecac ; evaporate to one-sixth of the original bulk, add to the powder in sufficient quantity to make a mass, and divide into lozenges of 7^ grains each. Lofotal. This is the name given to cod liver oil impregnated with carbon dioxid. The PROPRIETARY AND SYNTHETIC REMEDIES. 789. contained carbonic acid gas is said to hide the taste of the oil and preserve it by preventing oxidation. Lofotin. This is a so-called Irydroxyl-free steamed cod liver oil. It is also put up with .01% of phosphorus. Loretin. (Metaiodoorthooxyquinoline- sulfonic Acid.) This is a yellow, inodorous, crystal- line powder, sparingly soluble in water and alcohol, insoluble in ether and oils, but forming emulsions with ethereal and oily fluids (particularly with collodion). It is used externally as a substitute for iodoform. It contains 36% of iodin. It is also used internally in doses of 3 to 8 grains. Losophan. (Triiodometacresylic Acid Locock's Pulmonic Wafers. — Tri-Iodo-Cresol.) This is in white needles, which are easily soluble in ether, chloroform and warm fixed oils, sparingly soluble in alcohol, insoluble in water. It is used externally as an antipara- sitic in 1 to 2% hydroalcoholic (1 of water, 3 of alcohol) solution, or 1 to 3% ointment. Lotio Cinchonae Comp. (142) This is a preparation containing ole- ates of the alkaloids of cinclona, 15 grains to the ounce, 5 grains of this be- ing quinine; the oleates are dissolved in amylic alcohol. It is applied extern- ally when cinchona or quinine cannot be taken by the mouth as in night sweats of phthisis, etc. It is also applied ex- ternally in eczema and seborrhea and other diseases of the scalp and skin. Lotio Pancreatis. (70) This is described as "an extract of the pancreas of great trypsin strength, con- taining likewise all the soluble gland constituents in an active form." It is designed for topical application to can- cers, ulcers, carbuncles, etc. Loxalotio. See Lotio Cinchonae Comp. Lubraseptic. (176) This is a jelly prepared from Irish moss, containing 2% of boric acid and 0.067% of formaldehyde. It. is a color- less, transparent jelly almost completely soluble in water. It is claimed to be ab- solutely sterile. It is said to be a disin- fectant which is non-irritating to the skin or mucous membranes. It is claim- ed to be useful as a lubricant for the fin- gers or for surgical instruments and as a dressing for burns or slight abrasions. Lubri-Chondrin. (201) This is a gelatinous substance obtained from Irish moss with the addition of oil of eucalyptus and formaldehyde. It is used as a surgical lubricant. Lubrikol. (86) This is a soluble surgical lubricant stated to be made from Irish moss with the addition of oil of eucalptus and for- maldehyde. Lucilline. This is the name for a brand of puri- fied petrolatum. Luperine. This is a mixture of powdered col- umbo, gentian and quassia. — Coblentz. It is used as a remedy against dipso- mania. Lutein. These are tablets said to contain 5 grains of the dried yellow substance of the ovaries of the cow. Lycetol. (Dimethylpiperazine Tar- trate.) This is a white, odorless powder, slightly hygroscopic, and easily soluble in water, forming an agreeably acedu- lous solution. It is incompatible with alkalies which liberate the insoluble base. It is claimed to be a diuretic and uric acid solvent superior to piperazine. It is said to be well borne by the stomach. The dose is 5 to 10 grains 3 times a day well diluted with water, preferably car- bonated water, which may be sweetened with sugar if desired. ;90 THE STANDARD FORMULARY Lygosine. (Sodium Lygosinate.) This is a condensation product of salicylaldehyde and acetone. It crystal- lizes in glossy, greenish prisms, soluble in about 16 parts of water at the ordi- nary temperature. This solution is ruby red in color, is not decomposed by boil- ing, and will remain stable for some time if kept in a cool place; acids, how- ever, decompose it. This is used as an antigonorrheic remedy in place of silver salts, being suitable for male or female. Being non-irritant, it may be used in so- lutions of greater strength than may be used of silver salts. It is used in solu- tions of S% strength. Lygosine-Quinine. See Quinine Lygosinate. Lymph-Orchitic Fluid Compound. (Roberts-Hawley Lymph Comp.) (144) The following formula is given by the manufacturers in their advertisements : Lymph and lymph gland extracts (young goats). Orchitic fluid (goats and bulls). Brain and cord extracts (emulsions). Chlorid of Au and Na (1/40 gr. to 10 minims). Menstruum (described in literature). Lymphoids. (82) These are 5-grain tablets which are stated in the advertisement to contain Ext. testes and lymph (con- „ taining spermine and nuc- lein) gr. 2 "Phosphine" of zinc gr. 1/20 Ext. nux vomica gr. 1/8 Ferrous carb. mass (Blaud's)gr. 1 Aloin gr. 1/20 "Bovis pulv.," q. s. ad gr. 5 Lyptol. (12) This is an antiseptic ointment which is stated to be made from "hydrargyri bi- chloridi, oleum eucalyptus, formalin, and benzo-boracic acid, combined with a per- fectly sterilized petroleum base." Lysan. This antiseptic and disinfectant is ob- tained by the action of formaldehyde on certain terpenes, and allied substances (such as eucalyptol, menthol, eugenol, etc.), and then dissolving the reaction product in diluted alcohol. The prepa- ration is miscible in all proportions with water, glycerin, and alcohol, has a pleas- ant odor both when concentrated and when diluted, is quite stable, does not at- tack steel or nickel instruments, and is said to be but slightly toxic. It is used in from 0.5 to 10% solutions, for disin- fecting the hands, rooms, removing' odors, sterilizing instruments, etc. Lysargine. This is a name for colloidal silver. Lysidine. (Ethylene-Ethenyl- Diamine.) This is a bright red crystalline mass, which on account of its extreme hygro- scopic nature is marketed only as a 50% solution. This is a pale yellowish liquid. It is recommended as a diuretic and is recommended as a solvent of uric acid because it forms a very soluble com- pound with the latter and will facilitate its elimination from the system. It is claimed to be superior to piperazine. It is used for gout, lithiasis, etc. The dose is 15 to 75 minims, largely diluted in water, preferably carbonated water. Lysoform. This is a perfumed saponaceous liquid containing formaldehyde. It is a clear, yellowish, oily liquid, soluble in all pro- portions of water and alcohol. It is used as a disinfectant and deodorant, especial- ly of the hands, in 2 or 3% dilutions. Lysol. This is a saponaceous solution con- taining 50% of cresols. It is a brown, oily liquid, soluble in water, alcohol and glycerin. It is disinfectant and antisep- tic and is used as a dressing for wounds and injuries in l / 2 to 1% solutions and in 2 to 4%. solutions for disinfecting the hands and surgical instruments. Lysulfol. This is the name given to a compound of sulfur, lysol and soap, containing 10% of sulfur. It is a black semi-fluid readily soluble in water. PROPRIETARY AND SYNTHETIC REMEDIES. *91 Lytrol. This is said to consist of 20% of beta- naphthol in an alcoholic solution of po- tassa soap. MacAlister's Cough Mixture. This is stated to contain in each fluid- ounce Morphine sulfate gr. % Extract cannabis indica m. 7^ Chloroform m. HJ4 Magee's Emulsion. This is stated to contain cod-liver oil, diastasic extract of malt, and hypophos- phites of sodium and calcium. Magnesiathal (Lac Magnesii Hy- drati.) (142) This is stated to contain 8% of mag- nesium hydrate in aqueous suspension. Magnesium Dioxid. For preparations containing it, see Biogen and Magnesiumperhydrol. Magnesiumperhydrol. (130) This is a magnesium peroxid, which occurs as a white powder, insoluble in water, and containing 15 to 25% of mag- nesium peroxid (Mg0 2 ) and 7$ to 85% of magnesium oxid (MgO). It is rec- ommended for internal use as a disin- fectant and oxidizer in abnormal gastric and intestinal fermentative processes. It is given in doses of J4 to I teaspoonful 3 or 4 times a day. Magnesium-Tonol. (178) This is a name for magnesium glyce- rophosphate. Maizavena. (131) Each fluidram is stated to represent Saw palmetto (fresh ber- ries) gr. 15 Maizenic acid (from fresh corn silk) gr. 1/10 Avenine ( from oats) gr. 1/64 Oil santal m. 3 Maizine. This is an albuminoid principle derived from corn flour. It is a light, white powder, insoluble in water, soluble in alcohol and in acetone. It is recommend- ed as a coating for pills intended to dis- solve only in the intestines, thick alco- holic solutions (40% or more) being used for this purpose. Maizo-Lithium. (97) This is described by the manufacturers as "a nascent chemic union of maizenic acid, obtained from green corn silk, with the alkaline base lithium, forming maize- nate lithium, of which the mother liquid carries 2 grains to each drachm." It is recommended for genito-urinary dis- eases. Malakin. (Salicyl-paraphenetidin. ) This is in fine bright yellow needles, which are soluble in hot alcohol and in solutions of alkaline carbonates, slightly soluble in cold alcohol, insoluble in wa- ter. It is an antipyretic and analgesic, like antipyrine, and is also recommended as a tenifuge. The dose is 8 to 15 grains several times daily. Malarin. (Acetophenone-phene- tidin.) This is in yellow needles of slightly acid taste. It is insoluble in water, slight- ly soluble in cold alcohol, readily soluble in hot alcohol and ether. It is an anti- pyretic and analgesic, the dose being 8 grains 2 or 3 times a day. Malix. This is a proprietary dietetic prepara- tion supposed to consist of diastasic ex- tract of malt dissolved in grape juice. — W. D. Mallein. This is a serum used for diagnosing glanders in horses. It is marketed in the liquid as well as in the dry forms. Maltine. This is stated to be prepared from equal parts of malted barley, oats and wheat, presumably in the usual manner for making malt extracts. It is put up in various combinations such as the fol- lowing : With Cascara Sagrada : This is stated to contain the extract of 60 grains of cascara sagraaa to each fluidounce. With Coca Wine: Each fluidounce is stated to represent the virtues of 30 grains of coca. 792 THE STANDARD FORMULARY With Cod Liver Oil : This is stated to contain 30% of cod liver oil and 70% of maltine, both by volume. With Creosote: Each fluidounce is said to contain 4 minims of creosote. Ferrated : Each fluidounce is stated to contain 8 grains of iron pyrophosphate. With Hypophosphites : Each fluidounce is stated to contain 3 grains each of the hypophosphites of lime and soda and 2 grains of iron hypo- phosphite. With Peptones: This is described as a combination of digested beef with maltine. With Pepsin and Pancreatin : Each fluidounce is stated to contain pepsin equal to 40 grains of saccharated pepsin and 15 grains of pancreatin. With Phosphate Iron, Quinia and Strychnia : This is claimed to contain 4 grains of iron pyrophosphate, 1 grain of quinia, and 2/75 grain of strychnia, to each fluidounce. With Wine of Pepsin : Each fluidounce is stated to contain diastase sufficient to render digestible 12 ounces of starch and pepsin sufficient to render digestible 6 ounces of albumen. Maltobeef. (99) This is stated to be an emulsion of cod liver oil containing the hypophos- phites of lime, soda and potassa and the extracts of malt and beef. Malto-Fer. (Vinum Malti et Cin- chonae Ferratuni.) (142) Each fluidounce is stated to represent : Malt, as extractive, 120 grains ; cinchona calisaya, as aqueous extract, 16 grains ; iron, as maltose iron, 2 grains; combined with wine. Maltosikat. This is the name given to a malt ex- tract in powder form. Maltole. (79) This is a preparation of cod liver oil with malt extract. Maltopepsine. (194) This is stated to contain sugar of milk, "nutritives of the grain," diosco- rein, pepsin, diastase, and lactic, nitro- muriatic and phosphoric acids. Maltopepsine Elixir. Each fluidram is stated to contain 10 grains of maltopepsine. Maltopepsin Elixir with Glycero- phosphates. Each fluidram is stated to contain Sodium glycerophosph gr. 2 Calcium glycerophosph gr. I Iron glycerophosph gr. 3/16 Manganese glycerophosph. . .gr. 1/8 Strychnine glycerophosph. . .gr. 1/64 Elixir of maltopepsine, q. s. Malto-Yerbine. Each fluidounce is stated to contain the active principles of 30 grains of yerba santa. Maltzyme. (125) This is "a diastasic essence of malt, extracted and concentrated by a new process." It is put up plain and in com- binations as follows : With Cascara Sagrada : Each fluidounce represents 45 grains of cascara. With Cod Liver Oil : Contains 25% by volume of cod liver oil. With Hypophosphites : Each fluidounce is stated to contain Calcium hypophosphite gr. 4 Potassium hypophosphite gr. 4 Ferric hypophosphite gr. *4 Manganese hypophosphite ....gr. l A Ferrated : Each fluidounce is said to contain 8 grains of iron pyrophosphate. With Phosphate of Iron, Quinine and Strychnine : Each fluidounce is stated to contain 4 grains of iron pyrophosphate, 1 grain of quinine, and 2/75 grain of strychnine. PROPRIETARY AND SYNTHETIC REMEDIES. 793 With Yerba Santa : Each fluidounce is stated to represent 30 grains of yerba santa. Mandrake Compound. (17) This is stated to contain podophyllum, leptrandra, apocynum, cannabinum, ber- beris vulgaris and chionanthus. Manganauro. (Solution of Bromid of Gold, Arsenic and Manga- nese.) Ten drops of this are stated to con- tain 1/32 grain each of gold and arsenic bromids, and y 2 grain of manganese bromid. Manganese-Tonol. (178) This is a name for glycerophosphate of manganese. Manola. (126) According to an advertisement, this is stated to contain the cell or tissue phos- phates (calcium, magnesium, sodium, po- tassium and iron), all dissolved in Ma- deira wine. According to another ad- vertisement, this preparation contains be- sides these phosphates, "gaduline" (the active principle of cod liver oil), cin- chona, coca, and the extract of "mano nut." Maretin. This is a methylated acetanilid in which the acetyl group is replaced by urea. It is in white, glistening crystals, sparingly soluble in water (1 in 1050), more soluble in alcohol (1 to 95). It is used as an antipyretic in doses of 3 to 5 grains. Marienbad Pills. This formula was contributed to Pharm. Centralh. by the reputed origina- tor and given by him as the original formula : Extract of fucus marinus. . .parts 16 Salt of the Marienbad, natural parts 4 Sodium taurocholate parts 2 In^luvin part 1 Castoreum, Russian part 1 Extract of cascara sagrada, powder sufficient Make into pills weighing S T A grains each, and coat with silver leaf. Many other formulas have been given for these pills, purporting to furnish products the same as, or similar to, the original. Several of these formulas are in Hager's and Dieterich's works. Marina. This is a sterilized and carbonated sea water, used in place of the usual physio- logical salt solution. Markasol. (112) This is denned as bismuth borophe- nate ; and is a white powder of the odor of camphor. It is intended as an anti- septic dry dressing for wounds, ulcers, burns, etc. Marmorekin. This is Marmorek's antistreptococcus serum. Marrol. This is said to consist of ox marrow, malt extract, and hop extract. — Cob- lentz. Marshall's Catarrh Snuff. According to Hager, this consists of tobacco and leaves of Glechoma hedera- ceum, asarum, etc., the whole perfumed with oil of eucalyptus and traces of other oils. Marshall's Pills. Comp. ext. of colocynth gr. 60 Mass of mercury gr. 60 Rhubarb gr. 60 Aloes gr. 60 Soap gr. 60 Make 60 pills.— Ph. Rec. Marsitriol. This is a name for iron glyceroarse- nate. It is a yellowish, amorphous pow- der. The dose is 1/6 gram 3 times a day. Maukalan. This is an ointment-like substance used in veterinary practice, which con- tains thigenol as its active ingredient. It is recommended for saddle-gall, inflam- mations and malanders. McArthur's Syrup of Hypophos- phites Comp. This is stated to contain i2 x /> centi- grams of the hypophosphites of lime and 94 THE STANDARD FORMULARY soda to each teaspoonful, combined with a neutral syrup. It is said to be made according to the formula of Dr. Churchill of Paris. McClure's La Grippe Tablets. (181) These are made to contain each Sodium salicylate gr. 2 Acetanilid gr. V/2 Cerium oxalate gr. */2 Citrated caffeine gr. 3/2 MacDougall's Disinfecting Powder. This is said to be prepared by adding crude carbolic acid to sodium sulfite. — Frerksen. McMunn's Elixir of Opium. The manufacturers claim that it con- tains all the valuable medicinal prop- erties of opium in natural combination, to the exclusion of all its noxious, del- eterious or useless principles. Meatox. (127) This is described as a granulated dry beef, free from preservatives. Mecca Compound. (75) This is stated to be composed of men- thol, thymol, boracic acid, pyroligneous acid, carbolic acid, and eucalyptol, "com- bined in a plastic base of purified and prepared petroleum." Medicora. (Vaginal Pessaries of Solidified Glycerin.) (186) Each pessary is stated to contain 3 grains of ichthyol, 5 grains of lead car- bonate, 3 grains of zinc sulfate, 1 grain of extract of belladonna, and 5 grains of "fluid hydrastis" (yellow). Medicamentum. Same as Haarlem Oil, which see. Medullary Glyceride. This is the same as Extract of Red Bone Marrow, which see. Medulline. (213) This is an extract of the spinal cord. Melachol. (4) This is put up in two forms, liquid and an effervescent tablent form. The liquid is stated to contain 85 grains of "phosphates" with "nitrates" of sodium, 85 grains to the fluidram. The tablets are said each to contain- 35 grains of "phosphates" with "nitrates" of sodium. Melioform. This is a disinfectant which is said to be represented by the following formula, according to Zernek (in Ch. & Dr.) : Formaldehyde g. 25 Solution of aluminum acetate. g. 15 Borax g. 2.5 Glycerin g. 0.3 Water g. 100. Color red and flavor with bergamot. Mel-Maroba. (182a.) This is described as a palatable blend- ing of manaca, caroba, and stillingia, a fluidounce representing 120 grains of the combined drugs, together with 16 grains of potassium iodid. Mentho-Eucalyptol. This is stated to be composed of men- thol, thymol, eucalyptol, baptisia, gau- theria and "benzo-boracic acid" with 25% cologne spirits. Menthoxol. This is a 3% hydrogen peroxid con- taining 1% of menthol. It is used as an antiseptic application. Menthyseptic. (198) This is stated to be composed of thy- mol, menthol, eucalyptol, methyl salicy- late, and boric and benzoic acids. Mentone. (88) A name given to unfermented grape juice. Mercatone. (63) Each 10 minims is stated to contain Mercury bromid -s gr. 1/32 Gold bromid gr. 1/32 Arsenic bromid gr. 1/32 Mercauro. (Solution of Gold, Arsenic and Mercury Bromids.) Ten drops are stated to contain 1/32 grain each of gold, arsenic and mercury bromids. Mercuran. (69) This is an ointment containing 50% of mercury in goose fat stearin. It is put up in 4 g. capsules, the contents of each capsule being sufficient for one inunc- tion. PROPRIETARY AND SYNTHETIC REMEDIES. 795 Mercuralin Eye Salves. (153) These are stated to contain mercuric oxid and adrenalin. No. ]/+ contains Y\ L grain of yellow oxid of mercury and 1/400 grain of adrenalin to a dram ; No. y 2 is the same but contains y 2 grain of yellow, oxid of mercury; and No. 1 is the same but containing 1 grain of the yellow oxid. Mercuralin Compound is the same as No. y 2 with the addition of y grain of atropine sulfate. Mercolint. These are chest pads, made by Beiers- dorf, impregnated with mercurial oint- ment. They are used by syphilitics. They are made in three strengths, ac- cording to the amount of mercury they contain. Mercuramalgam. (Mercuriol.) This is said to be an amalgam of mer- cury with aluminum and magnesium, combined with chalk. It is a gray pow- der containing 40% of mercury. It is used both internally and externally. Mercurial Embrocine. (21) This consists of y of metallic mer- cury and Yz of a mixture of benzoinated lard and soap. Mercuricide Ointment, Eskay's. This is described as containing 1 part of mercuric iodid as lithiomercuric iodid in 1000 parts of aluminum silicate and lanolin, the whole being odorized with thymol. It is put up in 5-ounce ointment pots. This mercury compound is said to possess properties which make it su- perior to corrosive sublimate as a disin- fectant. The ointment is recommended for various skin diseases, especially those of an eczematous character. ~ Mercur-Iodo-Hemol. This is hemol (which see) combined with 12.4% of mercury and 28.6% of iodin. It is a brown powder, used as an antisyphilitic. The dose is 2 to 5 grams 3 times daily in the form of pills. Mercuriol. See Mercuramalgatn, Mercurods. (136) These are urethral crayons, each one of which is stated to contain 1/50 grain of mercuric iodid, % grain of zinc iodid, y grain of lysol, l / 2 grain of extract of henbane, 1 grain of antipyrin, and 2 grains of fluid hydrastis. They are rec- ommended for gonorrhea and ure- thritis. Mercurol. (Mercury TTucleinate.) (159) This is a compound of mercury with nucleinic acid from yeast, containing 10% of metallic mercury. It is a brown- ish powder, soluble in water, especially in warm water, insoluble in alcohol. It does not coagulate albumin. It is said to be a non-irritant. It is used for gon- orrhea, chronic conjunctivitis, blephari- tis, syphilis etc. It has marked bacteri- cidal power and possesses the pharma- cologic action of soluble mercury com- pounds. It is given in doses of ^ to 3 grains three times a day and locally in y 2 to 5% solutions. Mercurocreme. This is described as a neutral potas- sium stearate containing one-third mer- cury and . dissolved in glycerin. It is used locally as a substitute for mercurial ointment. Mercurovanillin. (Mercuric Vanil- late.) This is a compound containing 40% of mercury. It is a white, tasteless pow- der, insoluble in water and weak acids and of the odor of vanilla. It is used in syphilis. Mercury Anilinate. This is a white, odorless and tasteless powder containing 52% of metallic mer- cury. It is insoluble in water. It is ap- plied by inunction in the form of a 35% ointment in syphilis; to sores it is ap- plied as a y 2 to 3% ointment. Internally it is given in doses of J 4 grain. It is also used by intramuscular injections, rubbed up with paraffin oil. '96- TH E STANDARD FORMULARY Mercury Cyanid. This is in colorless, odorless, trans- parent prisms, which are darkened by light and hence should be kept in a dark place or in amber-colored bottles. It is soluble in 13 parts of water and in 15 of alcohol. It has the same properties as corrosive sublimate, but is preferred to the latter because much less irritating. The dose is 1/12 to 1/6 grain 3 to 5 times a day. Mercury Glycolate. This is a compound obtained by dis- solving mercuric oxid and glycocol to- gether in hot water. It is used as an intramuscular injection for syphilis. Mercury Oxycyanid. This is a white, crystalline powder soluble in hot water. It is used in place of corrosive sublimate because it is less irritating and is more active as a germi- cide. It is used in 0.2 to 2% aqueous solutions. Mercury Salicylate. This is a white powder containing 59% of mercury. It is insoluble in water and alcohol, but soluble in solutions of so- dium chlorid and in dilute alkalies. It is used for syphilis and gonorrhea. It is applied as a 1% powder or ointment and is used as an injection in a 1 to 300 mixture with a little acacia. Internally it is stated to be well borne by the stom- ach and not causing salivation. The dose is l A grain. Mercury Succinimide. This is a white powder soluble in about 25 parts of water, slightly soluble in alcohol. It is considered by many as the most eligible compound of mercury for hypodermic or intramuscular admin- istration. This is a good formula : Mer- cury succinimide, 2.5 ; cocaine hydro- chlorid, 1.0; distilled water, 50. 1 cc. of this solution is used for an injection Mercury Tannate. This is a greenish brown powder con- taining about go% of mercury. It is in- soluble in all ordinary solvents. It is used as an antisyphilitic in doses of 1 to 2 grains. Mercury Thymolacetate. This is in colorless crystals insoluble in water. It is used by intramuscular in- jections for syphilis, i l / 2 grains mixed with liquid paraffin or glycerin being in- jected every third or fifth day. Merrell's Vaginal Discs. Powdered ext. of helonias. . .gr. 12 Powdered ext. of hydrastis. . .gr. 12 Powdered ext. of henbane. .. .gr. 6 Powdered opium gr. 6 Eucalyptol gr. V/2 Thymol gr. V/i Gallic acid gr. 12 Boric acid gr. 36 Tannic acid gr. 24 Alum gr. 36 Make into 12 compressed tablets. Mesotan. (Ericin.) This is the methyloxymethyl ester of salicylic acid, analogous to oil of winter- green. It contains 71% of salicylic acid. It is a clear, yellowish, faintly aromatic, oily liquid, sparingly soluble in water, readily miscible with alcohol, ether, chloroform, and. fixed and volatile oils. It is applied externally in cases of rheu- matism. Inasmuch as it is quite irritant when applied tQ the sensitive skin, it is usually mixed with an equal volume of olive (or similar) oil. Metaphenylenediamine Hydrochlorid. This has been recommended for the treatment of diarrhea in infants and adults in doses of % to i l / 2 grains. Methacetin. (Paraacetanisidin — Acetylmethylparaamidophenol — "Oxymethylated Antifebrin.") This is a reddish-white, odorless, crystalline powder, of faintly saline-bit- terish taste. It is sparingly soluble in water, readily in alcohol. It is an anti- pyretic, which is used principally in chil- dren's diseases. Dose (child's) 2 to 5 grains. Methaform. (Dimethylcarbinol Chloroform.) (187) This is in white, shiny, needle-like crystals of a slightly camphoraceous odor and taste. It is sparingly soluble in water, but readily so in chloroform, ether, alcohol and glacial acetic acid. It PROPRIETARY AND SYNTHETIC REMEDIES. 797 is a hypnotic and antiseptic, somewhat like chloral in action. It is also used as a local anesthetic. See also Chlorbu- tanol. Methazin. This is a synonym for antipyrin. Meth-Solules. (89) Each capsule is composed of Methylene blue gr. i Para copaiba m. iy 2 Oil of cinnamon m. ]/ 2 Methyl or Methylene Bichlorid. (Richardson.) This is a mixture of I volume of methyl alcohol and 4 volumes of chloro- form. It has been recommended as a general anesthetic. On account of the poisonous character of the wood alcohol it should not be used. Methyl Rhodin. (Methyl Acetylsa- licylate.) This has the same relation to oil of wintergren that aspirin has to salicylic acid. It is described as a colorless, cry- stalline powder of a slight odor of win- tergreen. It is soluble in alcohol and fixed oils but insoluble in water. It is used as a substitute for the salicylates in rheumatism. Methyl-Santal. (Capsula Santali Comp.) (141) Each capsule is stated to contain Methylene blue . . gr. 1 Oleoresin of copaiba gr. 1% Oleoresin of cubeb gr. % Oil of sandalwood gr. 1V2 Oil of cinnamon gr. V 5 Oil of nutmeg gr. 1/12 Methylal. This is a colorless liquid, with an odor similar to that of chloroform, and a pungent taste. It is soluble in water, alcohol and oils. It is used as a local anesthetic; as a nerve sedative in deli- rium tremens, etc. ; antispasmodic in strychnine-poisoning, tetanus, etc. ; ano- dyne in gastric and intestinal pains, etc. It is used in the form of liniment with 6 parts of some bland fixed oil (1 to 6 sweet almond oil). The dose is 1 to 2 minims every 2 or 3 hours, well diluted Methylene Bichlorid or Chlorid. This is a colorless inflammable liquid of an odor like chloroform. It is rec- ommended as a local anesthetic. Do not confound with methyl or methylene bi- chlorid (Richardson). Methylene Blue. This is one of the so-called aniline dyes. It is in dark blue crystals or powder, soluble in about 50 parts of water, also soluble in alcohol. It is an antiperiodic, antineuralgic and antigon- orrheal. It is used externally in malig- nant tumors and ulcers. The dose is 1 to 5 grains in capsules or tablets 4 times daily, or 1 grain by injection. In ma- laria it is a specific even more so than is quinine. In the treatment of gonor- rhea it has been found useful especially in combination with various oils or bal- sams. When given internally it colors the urine green or blue. Methylene Blue Compound (Hor- witz.) On Dr. Orville Horwitz's recommen- dation, various manufacturers have put up a combination like the following in capsules or pearls : Methylene blue gr. 1 Copaiba balsam m. \ l / 2 Oil of santal m. i l / 2 Oil of cinnamon m. l / 2 Sometimes the oil of cinnamon is re- placed by methyl salicylate. Methyloids. (187) Each capsule is stated to contain Methylene blue gr. 1 Copaiba balsam m. i l / 2 Santal oil m. \ l / 2 Haarlem oil m. 1 Y+ Oil of cinnamon m. l / 2 Metral Disks, See Sanitaris Metral Disks. Metroglycerin. This is said to consist of a sterile so- lution containing 10% of neutral glyce- rin and 2% of gelatin, to which are add- ed various antiseptics. It is used as an intrauterine injection for producing uter- ine contractions. 798 THE STANDARD FORMULARY Metrowine. (146) This is an utero-ovarian tonic, each fluidounce of which is stated to contain blackhaw, 2.5 grams; blue cohosh, 1.5 grams; milifoil, 3 grams; sumbul, 1.5 grams; helonias, 1 gram; aletris fari- nosa, 1 gram, and "elixir aromatics," sufficient. Mialhe's Elixir of Pepsin. Pepsin g. 2.5 White wine g. 60 Simple syrup g. 50 Alcohol g. 5 — H. Microcidin. (Sodium Betanaph.th.o- late.) This is used as a surgical disinfectant in 3 to 5% solutions. It is an antipyretic in small dose's. Migrainin. (Antipyrin-Caffeine Citrate.) This is a mixture of antipyrin, 85 parts, caffeine, 9 parts, and citric acid, 6 parts. It is a white powder soluble in 2 parts of water, readily soluble in alcohol. It is an antipyretic and analgesic for migraine, neuralgias, sciatica, etc., the dose being 6 to 15 grains 2 or 3 times daily. A preparation of the same name is made by C. S. Baker & Co., the composi- tion of which is stated to be celery and detannated guarana. Migrol. This is described as a preparation of guajacetin and caffeine. It is recom- mended for all kinds of headaches, neu- ralgia, toothache, and all nervous affec- tions. The dose is 8 grains 1 to 3 times daily. Migrophene. This is quinine lecithin compound in which the taste of quinine is scarcely perceptible. It is used * for migraine, headache, influenza, etc., in doses of 5 to 8 grains. Milk of Bismuth. (159) This is a thick white liquid consisting of hydrated oxid of bismuth and traces of subcarbonate, each fluidram being said to contain the equivalent of 5 grains of bismuth subnitrate. Milk of Magnesia. (164) The process for this preparation was patented some years ago. According to the specifications of this patent, magne- sium sulfate and caustic soda or potash are dissolved separately in water, the so- lutions are mixed and boiled, and the precipitate is washed repeatedly with dis- tilled water. Mill's Pulmonic Syrup Comp. See Syrup Pulmonic Comp. Miller's Phosphorized Elixir Gen- tian. (134) This is stated to contain gentian, sherry, phosphoric acid, taraxacum, glyc- erin and aromatics. Miller's Universal Balm. (For- merly called Magnetic Balm.) This is stated to contain 62% of alco- hol, also camphor, red pepper, clove, oils of origanum, cinnamon, spearmint, eucalyptus, cajuput, cassafras and penny- royal, and water. Mirinol. This is the name applied to an anti- septic, hemostatic and disinfectant liquid said to contain 10% of formaldehyde and 3/10% of phenol. It is recommend- ed for the treatment of carcinoma, lupus and similar affections. Mischolin. (160) Each fluidram is stated to represent Zinc sulfocarbolate gr. 1/20 Bismuth subcarbonate gr. 1 Salol. .gr. 1/10 Calomel gr. 1/60 Pepsin (1:3000) gr. 1/4 Aromatics, q. s. It is recommended for cholera infan- tum. Mistura Corrigens (Patch.) See Corrective Mixture. Mistura Quinqui Iodidorum. (Mix- ture of Five Iodids.) Each fluidram is stated to contain Arsenic iodid gr. 1/24 Mercury iodid gr. 1/24 Iron iodid gr. Y 5 Manganese iodid gr. V 5 i Potassium iodid gr. 2Ms PROPRIETARY AND SYNTHETIC REMEDIES. 799 Mixture Creosote Compound. (90) This is stated to be a nutritious and stimulating glyconin emulsion of beech- wood creosote and "etherized cod liver oil," each fluidounce representing 4 min- ims of creosote. Mixture Glyconin Comp. (180) This is stated to contain Cod liver oil . .parts 40 Sherry wine parts 40 Phosphoric acid parts 1% Egg, glycerin and carmina- tive aromatics, to make, .parts 100 No gum ; no sugar. Mixture of Hydrastis Compound. See Schlotterbeck's Compound Mix- ture of Hydrastis. Mixture Phosphorus Comp. (43) This is stated to contain in each tea- spoonful Mother tinct. of chamomilla.m. 2 Mother tinct. of nux vomica. m. 2 Mother tinct. of ignatia m. 2 Mother tinct. of cinchona. . .m. 2 Phosphorus gr. 1/100 Aromatics. Mollin. (Sapo Unguinosus.) This is a potash soap containing an excess of fatty acids and glycerin. It has been employed as an ointment vehicle. Mollosin. (Mollisin.) Yellow wax part 1 Liquid petrolatum part 4 —Ph. Ztg. Monobromphenol, Ortho-. This is a dark-violet liquid of a strong odor. It is soluble in water, alcohol and ether. It is a non-irritant external anti- septic (in erysipelas particularly). It is used in 3 to 6% ointment, rubbed in for 1 minute, twice daily. Monochlorphenol, Ortho-. This is a volatile fluid which is used by inhalation as an antiseptic in ozena, laryngitis, bronchitis, and pulmonary tu- berculosis. Monotal. (Guaiacol Ester of Ethyl- glycolic Acid.) This occurs as a colorless, oily liquid of an aromatic odor. It is very slightly soluble in water, easily so in alcohol, ether, chloroform and oils. It is used like guaiacol externally for rheumatism, etc., being rubbed on lightly or applied with a brush. It is said to be less caus- tic than guaiacol. Morgan's Quincoca. See Quincoca. Morgan's Sabalol. See Sabalol. Morgan's Tissue Food. See Tissue Food. Morgan's Vaginal Wafers. See Vaginal Wafers. Mormon Bishop Pills. According to the U. S. Department of Agriculture, this remedy consists of three kinds of pills, red, white and blue, but the composition is about the same. They contain capsicum, starch and a bit- ter principle. Morrholine, Ferrated. (174) This is said to be the active principles of cod liver oil with the glycerophos- phates of lime and soda, and' organic iron. The same firm also markets Morrholine with Creosote, and Morrho- line, Arseniated, with-Strychnina. Morrhuol (Chapoteaut.) (204) Morrhuol is a so-called alcoholic ex- tract of cod liver oil (see also Gaduo! and Jecorol). It is a brown liquid which is stated to represent 25 times its weight of cod liver oil. It is put up in capsules, the contents of each one being stated to possess the therapeutic activity of 1 lea- spoonful of the oil. Morrhuol Creosote (Chapoteaut.) Each capsule is stated to contain 3 minims of morrhuol and 1 minim of beechwood creosote. Morrison's Pills. These are of two kinds, Nos. 1 and 2. Pills No. 1 are composed of aloes and cream of tartar, equal parts, made into a mass with syrup or mucilage, and di- vided into 3-grain pills. The No. 2 are composed of the fol- lowing : 800 THE STANDARD FORMULARY Colocynth part i Gamboge parts 2 Aloes parts 3 Cream of tartar parts 4 Make into a mass with syrup and di- vide into 3-grain pills. — Cooley. Morumalt. (Morrhumalt.) (217) This is stated to contain Morrhuol 25 Extract of malt 25 Comp. syrup hypophosphites. . . . 25 YeiDa santa, wild cherry and flavoring 25 It is further described as a prepara- tion of morrhuol, malt, and wild cherry, combined with hypophosphites of lime and soda. It is also put up in combina- tions such as the following : With Cascara Sagrada : Each fluidounce is stated to contain 40 minims of "cascara sagrada aromatic." With Codeine and Terpin Hydrate : Each fluidounce contains 1/16 grain of codeine and 1 grain of terpin hydrate. With Creosote and Guaiacol : Each fluidounce contains 3 minims of creosote and 2 minims of guaiacol. With Hypophosphites : Each fluidounce contains 2 grains each of the hypophosphites of lime and soda and 1 grain of iron hypophosphites. With Iron and Manganese : Each fluidounce is stated to contain 8 grains of the pyrophosphates of iron and manganese. With Iron, Quinia and Strychnia : Each fluidounce is stated to contain Iron pyrophosphate gr. 4 Quinine pyrophosphate ....gr. 1 Strychnine pyrophosphate . .gr. 1/100 With Liquid Peptones (Ford's) : Each fluidounce is stated to contain the nutritive properties of i l / 2 ounces of beef. Mother's Joy, The. This is said to be made as follows : Chloroform drops 10 Tincture of saffron m. 30 Honey dr. 4 Glycerin oz. 1 It is a preparation applied to the gums of children while teething. Motherwort Compound. This is stated to contain fluid extract of motherwort combined with golden seal, cramp bark and oil of rue, the whole flavored acceptably. Mouches de Milan. Rosin 65 Venice turpentine 50 Yellow wax 22 Suet 2 Cantharides, powder 30 Euphorbium, powder 10 Storax, liquid 5 Oil of thyme 1 Mix together by melting, spread upon silk tissue, and cut into small rectangular pieces. — H. Moussette's Neuralgia Pills. (44) Each pill contains Vs milligram of pure aconitine and 5 milligrams of qui- nine. Mucogene. This is said to be "chlorid of dimethyl- phenyl - para - ammonium - and - oxyna- phthoxazine" and is defined as a new synthetic laxative. It is put up in cap- sules, two or three of which are a dose. Muiracithin. (139) The main constituents are stated to be muira puama and lecithin. It is rec- ommended for sexual neurasthenia. Mure's Syrup Bromid Potash. Potassium bromid...." g. 10 Simple syrup g. ioo Mix and dissolve. — H. Muscarine Nitrate. This occurs as a deliquescent mass, soluble in water and alcohol. It is an antihydrotic and antispasmodic in doses of 1/32 to 1/16 grain. Musculine. This is described as. the sterilized ex- tract of the muscular tissue of the ox. It is recommended for convalescence from severe diseases, being stated to be superior to beef extracts or beef tea. Musculon. This is stated to be prepared from muscular tissues by digestion with pan- creatic juice. It is stated to have the property of aiding the liver in the split- ! ting up of grape sugar. PROPRIETARY AND SYNTHETIC REMEDIES. 801 Mycodermine. This is the name given to an extract of yeast which is marketed in the form of pills or tablets. It is recommended for boils, etc. Mydrine. This is a combination of two myd- riatics, ephedrine and homatropine hy- drochlorids (100:1). It is a white pow- der, soluble in water. It is used as a mydriatic (especially where evanescent mydriasis is desired — in diagnosis, etc.). It is used in the form of a 10% solu- tion. Mydrol. (Phenylpyrazoliodomethy- late.) This is a white, odorless powder which is freely soluble in water. It is used as a mydriatic in 5 to 10% solu- tions. Myelocene. This is a preparation of bone mar- row, prepared by extracting the marrow with ether, evaporating the latter, and mixing the residue with 1% of chlore- tone for preservation. Myronin. This is an ointment vehicle composed of stearin soap, carnauba wax, and dceg- ling oil. Myrrholin. This is a solution of the resin of myrrh in castor oil, used as an applica- tion to wounds. Myrtol. This is derived by fractional distilla- tion of the oil of myrtus communis. It is a colorless liquid of aromatic odor. It is recommended as a disinfectant in putrid bronchitis and diseases of the respiratory tract. The dose is 5 minims every 2 or 3 hours. Naftalan. This is stated to contain 96% of a crude naphtha derived from a spring in the Caucasus and to this added 4% of anhydrous soap to impart consistency. It is in the form of a blackish-green, ointment-like mass of an empyreumatic odor. It is insoluble in water, water or glycerin but is readily miscible with fats. It is said to be anodyne, antiphlogistic, antiseptic and antiparasitic and is rec- ommended for burns, erysipelas, ecze- mas, etc. Nalicin. This is a local anesthetic in use by German dentists. It is said to consist of a mixture of 1% spirit of nitrogly- cerin, 1% cocaine hydrochlorid, "com- pound spirit of thymol," phenol, sodium chlorid, formaldehyde, alcohol and water. Napeline. This is one of the alkaloids from Aconitum napellus. It is a white pow- der, soluble in water, alcohol and ether. It is used as an anodyne and antineu- ralgic in lumbo-sciatic neuralgia, rheu- matic pains, etc., Dose : % to l / 2 grain. Na-Phoskol. According to the manufacturers, each fluidram contains 70 grains of sodium phosphate and 5 grains of sodium ni- trate. Naphthalin. (Naphthalene.) This is a hydrocarbon derived from coal tar. It is in white lustrous scales of a peculiar odor, insoluble in water, soluble in alcohol, ether, and oils. It is used as an intestinal antiseptic in doses of 2 to 8 grains. It is also used for tapeworms, 15 grains being given at a dose, to be followed in 2 to 4 h'ours by a cathartic. It is used externally in some skin diseases in the form of a 5 to 10% ointment. Naphthocresol. This is a mixture of phenols and cresols dissolved in a solution of resin soap. Naphthoformin. This is prepared by the action of formaldehyde on naphthol. It is a white crystalline substance soluble in water or alcohol, insoluble in ether or oils. It is used in dermatology. 802 THE STANDARD FORMULARY Naphthol(Alpha.) This is a constituent of coal tar. It is in colorless crystals, of a carbolic odor and a burning taste. It has been used as an antiseptic, both internally and externally. Being more toxic than bet- anaphthol, it is used but seldom. Naphthal Benzoate. See Benzonaphthol. Naphthol(Beta.) This is a constituent of coal tar and is also derived from naphthalene. It is in white scales or crystalline powder. It is insoluble in water, very soluble in alcohol, ether and chloroform. It is an antiseptic and antizymotic, useful es- pecially in fermentative conditions of the intestinal canal. The dose is 2 to 8 grains. It is also used externally in solu- tion or ointment, for many skin diseases. Naphthol Camphor. (Camphorated Naphthol.) A syrup liquid prepared by fusing together 1 part of betanaphthol and 2 parts of camphor. Naphthoxol. This is said to be a mixture of a 2% alcoholic solution of naphthol and a 3% solution of hydrogen dioxid. It is rec- ommended as a powerful germicide in the treatment of wounds. Narceine Hydrochlorid. Narceine is one of the alkaloids of opium. The hydrochlorid is in colorless needles, which are soluble in water and alcohol. It is employed as a hypnotic in doses of V& to 1 grain. Narceine-Sodium and Sodium Sa- licylate. See Antispasmin. Narcoform. This is a name given to a mixture of 12 parts of ethyl chlorid, 7 parts of methyl chlorid and 1 part of ethyl bromid. Narcotile. This is stated to be methyl-ethylene bichlorid. It is a transparent, highly volatile, and very inflammable liquid. It is a disinfectant, intended especially for use in dental practice. In its anes- thetic action it is stated to resemble ether. Narcotine. This is one of the alkaloids of opium. It is in colorless crystals, insoluble in water, but readily soluble in alcohol and ether. It is used as an antiperiodic for malarial fever in doses of 1^2 to 3 grains every two or three hours. Narcyl. (Ethyl-Narceine Hydro- chlorid.) This is in acicular crystals soluble in 120 parts of cold water, more soluble in warm water and in the presence of cinnamates, benzoates, citric acid, etc. It is used as an antispasmodic and ano- dyne for coughs, whooping cough, asth- ma, etc., in doses of 1 grain per mouth; in spasmodic crises of the respiratory tract, it may be given hypodermically in doses of y 6 to Yi grain. Nargol. (Silver Nucleide.) This is a compound of silver and nu- cleinic acid containing about 10% of silver. It is a light brownish-white pow- der, readily soluble in warm water, the solution not being precipitated by so- dium chlorid or other reagents for sil- ver, also not by albuminous substances and hence is more penetrating than inor- ganic silver compounds. It is strongly bactericidal and is recommended in the treatment of gonorrhea, etc., as a sub- stitute for silver nitrate in the form of 34 to 5% aqueous solutions. Nasrol. See Symphorol. Natroline. (93) This is described as a "purified petro- leum for internal use," "odorless, taste- less, antiseptic." Neat's Bronchiline. See Bronchiline. Nectriamin. This is a liquid preparation from cul- tures of Nectria ditissima, a so-called cancer parasite found on trees. It has been used in the treatment of cancer, PROPRIETARY AND SYNTHETIC REMEDIES. 803 not as a cure, but simply as a palliative for some of the symptoms. Neisser's Oil. This consists of mercury, 20 parts, ethereal tincture of benzoin (i. e., ben- zoin dissolved in ether instead of in al- cohol), 5- parts, and liquid petrolatum, 40 parts. Nenndorf Sulfur Soap. This is described as a superfatted sul- fur soap, which is made in two strengths, viz., 16% and 36% of sulfur. The sulfur used is that derived from the sulfur spring of Nenndorf, Ger- many. It is used for acne, sycosis, ec- zema, and psoriasis. Neodermin. This is an ointment containing lanolin, 85, petrolatum, 10, difluordiphenyl, 4, and fluorpseudocumol, 1. It is recommend- ed as an application for ulcerated sur- faces, lupus and various other skin dis- eases, and is also useful for burns. It is put up in collapsible tubes. Neoferrum. (124) This is denned as "malto-peptonate of iron and manganese with maltine (ar- senicated)." It is also stated to con- tain "maltine attenuated with sherry." Neoside. This is the name given by a French manufacturer to an iodo-catechin made by adding iodin in minute portions at a time to a hot alcoholic or aqueous solution of catechin. When the liquid cools, a yellow, amorphorus powder is obtained which is sparingly soluble in water but readily in alcohol, ether or acetone. It is recommended as a sub- stitute for other iodin preparations, both for internal and external use. When taken internally it is said to disturb the system less than other iodin compounds. Nepenthe. This is an English preparation of opium. Nephritic Pills. (211) These are stated to contain apiol, podophyllin, oil of juniper, potassium , 51 nitrate, and extracts of buchu, asparagus seed, and digitalis. Nephritin. (167) This is described as "the primary sub- stances of the cells of the cortex and convoluted tubules of the kidney." It- is put up in 5-grain tablets. Ner-Vig-or Syrup(Huxley.) Ner-Vigor Tablets(Huxley.) A name for Glycerophosphates (Huxley), which see. Nervitone Tablets. (212) Each tablet is stated to contain Phosphorus gr. 1/100 Ext. nux vomica gr. 1/10 Ext. of sumbul gr. y 2 Asaf etida gr. J / 2 Iron carbonate gr. i l / 2 Nervocidine. This is the name applied to the hydro- chlorid of the alkaloid derived from an Indian plant called gasu-basu. It is a yellow, hygroscopic powder, readily sol- uble in water, less soluble in alcohol and ether. It has been used as a local anes- thetic in dentistry in V 5 to %% solutions. Nervol. This is stated to be a mixture of citrozon (which see) with 10% of lith- ium bromid. Neufaline. According to Hager, this is petroleum ether (benzine.) Neuraline. According to Hager, this is a com- pound of about the following : Tincture of aconite 10 Tincture of opium 3 Chloroform 5 Spirit of peppermint 5 Neurilla. (54) This is described as containing "the essential (anti-nervous) active principles of Scutellaria and aromatics." Neurobion. Each cc. is stated to contain approxi- mately, phosphorus, .01 g\, arsenic, .C00066 mg., iodin, .000066 mg., all in organic combination, and anacardium, ignatia, and trinitrophenol, each .000075 mg. 804 THE STANDARD FORMULAR"! Neurocaine. (Billets of Cocaine.) (179) Each billet contains 1/12 grain of co- caine hydrochlorid without excipient. The billets are l /& inch long and 1/20 inch in diameter. They are used for pressure anesthesia or as a local anes- thetic in dental practice. Neurodin. (Acetyl-para-oxy-phenyl- urethane.) This is a colorless, odorless, crystalline powder, soluble in 1,400 parts of cold and in 140 parts of boiling water. It is a prompt antineuralgic in migraine, rheumatic pains, sciatica, locomotor ataxia, etc., acting within half an hour ; also an antipyretic in typhoid, pneu- monia, scarlatina, etc. The dose as an antineuralgic is 15 to 25 grains, as an antipyretic, 8 grains. Neuroguaiacol. A mixture each teaspoonful of which contains 1^/2 grains of calcium glycero- phosphate and i l / 2 grains of guaiacol. — Pharm. Centhalh. Neuro-Lecithin. (1) This is a preparation containing leci- thin with small amounts of fats and cholesterin. It is said to be made from the brain and spinal cord of animals. The water and fat are separated by heat, the soluble portions are extracted from 'the residue with ether, and this is pre- cipitated with acetone. It is put up in pills and tablets each containing l / 2 grain. Neuronal. (Bromdiethyl Aceta- mide.) This is a crystalline substance of a bitter taste and a faint odor of cam- phor. It is soluble in alcohol, ether or chloroform, and in 115 parts of water. It is used as a hypnotic in doses of 8 to 15 grains. Neuronidia. (Elixir Diethylmalony- lurea.) (179) This is said to contain in each 2 fluid- drams, 4 grains of veronal (diethylmal- onylurea) in a menstruum containing ZS^ of alcohol, with aromatics. Neurosin. A French preparation (in syrup or granule form), which contains as an active constituent calcium glycerophos- phate. — Coblentz. Neurosine. (64) It is claimed that each fluidram con- tains 5 grains each of c. p. bromids of potassium, sodium and ammonium, z /i grain of zinc bromid, 1/64 grain each of extract of belladonna, henbane and cannabis indica, 4 grains of extract of lupulin, and 5 minims of fluid extract of cascara, with aromatic elixirs. Nichol's Elixir Peruvian Bark with Protoxide of Iron. (22) This is described as a combination of iron with Peruvian bark in a pleasant and permanent form. Each fluidounce is stated to contain 6 grains of oxid of iron and the equivalent of 10 grains of solid extract of cinchona. Nichol's Tasteless Cod Liver Oil. This is stated to contain 15% of pure cod liver oil, about 30% of syrup of hy- pophosphites including . quinine, man- ganese and iron, 20% of fluid extract of wild cherry, and 15% of extract of malt. Nicolicin. This was a German proprietary rem- edy vaunted as a cure for the morphine habit, but which was found to consist of fluid extract of cinchona with sali- cylic acid, glycerin and morphine. The proportion of the latter varied from 2 to 4%. Nigridine. (Thyro-Iodose.) (169) This is described as a compound of iodin with concentrations of the thyroid and thymus glands of the sheep. Nirvanin. This occurs as a white, odorless pow- der or small crystals which are soluble in water or alcohol. It is a local anes- thetic and is used as a substitute for cocaine in 1 to 5% solutions for various minor or major operations and in dent- istry for devitalizing nerve pulps and for painless tooth extractions. It is said PROPRIETARY AND SYNTHETIC REMEDIES. 805 to be but very slightly toxic as compared with cocaine. Its solution is also anti- septic so it is not necessary to boil it although boiling does not decompose it. Nitrogenized Iron. (17) This is stated to consist of egg albu- men, ferric oxid, soda, and sugar. It is used as a tonic and hematinic. Nitrogenized Iron Improved, contains nitrogenized iron, manganese and ar- senic. Nizin. (32) This is a zinc salt of sulfanilic acid. It is readily soluble in water, is an anti- septic and is said to be non-irritant and non-toxic. Even in strong solutions it does not coagulate albumen. In the proportion of i grain to the ounce, it is used as a urethral injection in gonor- rhea. It is also used as a vaginal in- jection in the proportion of 2 or 4 or even 6 grains to the ounce. Nizolysol. This is a lysol preparation which pos sesses the ordinary properties of lysol but differs from it in odor, being pleas- ant and aromatic. Normalin. (36) This is stated to be composed of "hemoglobin and serum-albuminate of arsenic." It is recommended for "de- generative lesions of malnutrition." Normalin with Digitalis contains in addition to the above 1 minim of fluid extract of digitalis to the fluidram. Normalin with Manganese consists of normalin to which is added 1 grain of "nucleo-albuminate of manganese" per fluidram. Norton's Chamomile Pills. Extract of aloes, aqueous gr. 60 Extract of gentian gr. 180 Oil of chamomile drops 20 Make 60 pills. — Cooley. Norwich Urethral Crayons. (148) Each crayon is stated to contain Corrosive sublimate gr. 1/200 Zinc sulfocarb gr. 1/16 Golden seal, powder gr. 1/16 Morphine sulfate gr. 1/12 "Alum (non-irritating)" gr. Vz Cocoa butter, q. s. They are recommended for gonorrhea and gleet. Nosophen. (Iodophene— Tetraiodo- phenolphthalein.) This is a grayish, odorless, tasteless powder, containing 60% of iodin. It is soluble in alkalies, somewhat soluble in chloroform and ether, slightly soluble in alcohol, but insoluble in water or acids. It is used as an antiseptic like iodioform, as a dusting powder for burns, wounds, ulcers, etc. Its sodium salt is called antinosin, its bismuth salt eudoxin, the mercury com- pound apallagin. Nourry's Iodinated Wine. This is stated to be composed of Iodin , g. 3.3 Tannin g. 6.6 Sweet wine liter 1 Each tablespoonful is stated to con- tain 5 eg. of iodin combined with 10 eg. of tannin. Novargan. (Silver Proteinate.) This is albumin compound of silver containing 10% of metallic silver. It is a fine yellow powder, very soluble in water, the solution not being precipitated by sodium chlorid or the usual reagents for silver salts. Solutions must not be heated and must be protected from light. It is a bactericide and is claimed to be more effective and less irritating than other protein-silver compounds. It is said to be useful for the treatment of gonorrhea, especially as an abortive in the first stage. For this purpose 8 min- ims of a 15% solution is to be instilled through a catheter on the anterior sur- face of the urethra. Noyaspirin. This is the methylene-citric-acid ester of salicylic acid, and is recommended as a substitute for salicylates. It is a white crystalline powder of a slight sour taste, readily soluble in alcohol, almost insol- uble in water. It contains 6j r ( ' of sali- cylic acid. It is given in influenza, colds 80G THE STANDARD FORMULARY and rheumatism in doses of 15 grains several times daily. Novocaine. This is in fine, colorless needles, solu- ble in an equal weight of water, in 30 parts of alcohol. The aqueous solution of the salt may be heated to boiling without decomposition. It gives precipi- tates even in very dilute solutions with the usual alkaloidal reagents. It is also incompatible with alkalies and their carbonates. It is a local anesthetic sim- ilar to cocaine but is said to be far less toxic than any of the cocaine substitutes. When injected subcutaneously it is said to exert a prompt and powerful anes- thetic action but the effect is not sus- tained. This may be remedied by the simultaneous injection of suprarenal al- kaloid. Novocaine Base. This is the base of novocaine, the lat- ter being a salt. This base is soluble in almond or olive oil up to 10% if gently warmed on a water bath. This solution is of use in the treatment of diseases of the ear, nose and throat. Novocaine Nitrate. This is a chemical similar to novo- caine, having the same properties and sold at the same price. Novozon. This is the name applied to a mix- ture of magnesium dioxid and magne- sium carbonate. Noxinol. This is a photographic developer which is stated to be the sodium salt of rosolic acid. It is claimed that the addition of this chemical to any develop- er does away to a considerable extent with the necessity for dark chamber and the use of red light. Nuclein. This is a phosphorated proteid which was first prepared from the nucleus of cells, then from egg yolk and spleen pulp, but now generally from yeast. It occurs as a grayish-white, amorphous powder, only very slightly soluble in water, insoluble in alcohol or ether, sol- uble in dilute alkalies, especially upon heating. It is a germicide, and its action is marked by the fact that it increases the number of white corpuscles. To this is ascribed its good effect in pleurisy, pneumonia, and infectious dis- eases. It is used largely in the treatment of tuberculosis. The dose is 2 to 4 grains three times a day. Nuclein Solution and Capsules. (159) Nuclein Solution No. 1 contains 5% of nucleinic acid from yeast and is in- tended especially for hypodermic use. The No. 2 solution also contains 5% of nucleinic acid but differs from the No. I in containing albuminous matter derived from the source of production. Nuclein Solution, Veterinary, also con- tains 5% of nucleinic acid from yeast and is also intended for hypodermatic use. Nuclein Capsules each contain 2 grains of dry nucleinic acid from yeast. Nucleogen. This is a compound of nucleinic acid with iron and arsenic. It is marketed in tablet form with .05 g. of this compound to the tablet, also in the form of a solu- tion for hypodermic use, each cc. of which contains 1/10 g. The preparation is stated to be a general tonic. Nucleo-Peptone(Ford-Winslow.) (217) Each fluidounce is stated to contain Beef jelly .. gr. 8 Nucleinic acid gr. 2 Bitter orange peel gr. 6 Brandy and flavoring, q. s. It is described as a nutritive tonic and germicide useful for nasal catarrh, in convalescence from pneumonia, typhoid fever, puerperal fever, etc. Nuclo Ferri-Mangan. (81) Each teaspoonful is stated to contain Albuminate of iron gr. 2 l A Albuminate of manganese gr. I Nuclein solution drops 2 It is recommended for anemia, chloro- sis, amenorrhea, tuberculosis, etc. PROPRIETARY AND SYNTHETIC REMEDIES. 807 Nu Tone. (150) This formula is given : Cod liver oil, Malt extract, Beef juice, "Glycerine emulsion," each, 25%. Hypophosphites of lime and soda, each, gr. 1 Tincture of nux vomica, drops 1 in each teaspoonful. Nutritive Hypophosphites. (131) Each fluidounce is stated to contain Calcium hypophosphite gr. 1 Sodium hypophosphite gr. 1 Manganese hypophosphite . .gr. 1 Potassium hypophosphite ...gr. i l / 2 Iron hypophosphite gr. i 1 /^. Quinine hypophosphite gr. 7/16 Strychnine hypophosphite ...gr. 1/16 Nutritive. (162) Each teaspoonful represents ZZVz% of an alcoholic extract of cod liver oil (prepared from fresh cod livers), with 3 grains of hypophosphite of lime, l l / 2 grains of hypophosphite of soda, com- bined with malt, wild cherry, and port wine. Nutrolactis. (151) It is stated that the fluid extracts of the plants Galega officinalis, G. apolinea and G. tephrosea. It is used as a galact- agogue. Nutronmlsion. (131) This is stated to be an emulsion con- taining 50% of cod liver oil with eggs, brandy and phosphates. Nutrose. (Casein-Sodium — Sodium Caseinate.) This is the sodium salt of milk casein, containing 65% of proteids. It is pre- pared by dissolving moist casein, freshly precipitated from skimmed milk and washed with water in solution of sodium hydrate, evaporating the solution to dry- ness in vacuo, powdering the residue, washing it successively with alcohol and ether, and drying. It is a coarse, white, odorless and tasteless powder which is soluble in water. It is incompatible with acids. It is recommended as a non-irri- tant nutrient in wasting diseases, such as the cachexias in carcinoma, anemia, dia- betes, etc., and in acute and chronic feb- rile ailments such as pneumonia, typhoid fever and tuberculosis. The dose, 1 to V/2 ounces a day, is best taken in soup or milk. Nutryl. (79) This is described as "containing the normal bases of the lecithins, protagon, nuclein, neurin, etc., combined with the extract from naturally germinated cer- eals, barley, wheat and oats." Obtundo. This is the name applied to a local anesthetic intended for dental use, which contains chloretone, cocaine, nitroglyce- rin, thymol, menthol and the oils of win- tergreen, eucalyptus and clove. Oculine. A solution in ordinary water contain- ing 1% of boric acid and 5% of glycerin. —Ph. Rundsch. Odda. This is the name applied to a new in- fant's food which is distinguished chiefly by the replacement of the fat of cows' milk by egg yolk and cocoa butter. The food also contains partly digested flour and sugar. Odontodol. This is said to be a mixture of Cocaine hydrochlorid part 1 Cherry-laurel water part 1 Tincture of arnica parts 10 Sol. of ammonium acetate, .parts 20 Odontunder. This contains 1.35% of cocaine hydro- chlorid with some carbolic acid, glycerin, oil of rose, and probably alcohol. — Sadt- ler. Oidtmann's Purgative. Buckthorn, cut gr. 100 Jalap, powder gr. 100 Tobacco leaves, cut gr. 50 Sodium nitrate gr. 50 Sodium sulfate gr. 50 Magnesium sulfate gr. 50 Potassium carbonate gr. 38 Sodium chlorid gr. 23 Potassium hydrate gr. 40 Oil of anise drops 3 Oil of wintergreen drops 5 Castor oil fl.dr. 5 SOS THE STANDARD FORMULARY Alcohol fl.oz. 2 Glycerin fl.oz. 9 Distilled water sufficient Mix the first 10 ingredients with 11 fluidrams of alcohol and s l A fluidounces of water; macerate for several days in a warm place, agitating frequently; strain, to the colature add the castor oil mixed with 5 fluidrams of alcohol, and a solution of the caustic potash in enough water to make 6 l /> fluidrams, and to the whole add the glycerin. — Ha- ger. A thimbleful is to be injected into the rectum after stool, for hemorrhoids and various affections of the bladder, kidneys and uterus. Olans. These are compounds of petrolatum which have the property of forming emulsions with water in the proportion of 1 part to 5 up to 1 part to 2. These emulsions are stable and do not separate. They have no caustic action and are easily absorbed by the skin. Various compounds are prepared, such as iodo- lan, naphtholan, etc. Oleite. This is a jelly-like ointment vehicle obtained by acting upon castor oil with sulfuric acid. Oleocreosote. (Creosote Oleate.) This is a chemical combination of creosote and oleic acid containing t>2>% of the former. It is a yellowish, oily liquid, neutral and non-caustic, soluble in chloroform or ether, not in alcohol or water. It is used in the treatment of catarrhal affections of the respiratory tract, in influenza, scrofula, etc., the daily dose being l / 2 to 2 l / 2 fluidrams. Oleo-Maltose. (36) This is stated to contain maltose, milk peptone, saw palmetto, the mixed hypo- phosphites (lime, soda and potassa), and cod liver oil 2>zVz7c. Oleo-Maltose with Creosote contains in addition to the above 8 drops of creo- sote to the fluidounce. Oleo-Stearate of Zinc (Chappell's Formula.) See Emoleo. Oleoze Co. Oil of lavender oart Oil of clove part Oil of cinnamon part Oil of thyme part Oil of citron part Oil of mace part Oil of neroli part Peru balsam parts 3 Deodorized alcohol parts 240 Oliophen. This is said to be a solution of salol in olive oil containing also some constit- uents of linseed. It is used internally as an antigonorrhoic in doses of 30 drops 3 times daily. Olivier's Biscuit's Depuratif. According to Hagerf these are biscuits made with sugar and milk, each one weighing 16 g. and containing 1 centi- gram of corrosive sublimate. Omorol. This is the name given to an albumin- ate 01 silver, insoluble in water, but which passes into solution in the tissues and secretions of the body. It is a bac- tericide recommended in the local treat- ment of diphtheria. Opotherapeutics. The so-called "opo" substances are the active principles, which are the leuco- maines, of the various organs, thymus, thyroid gland, spleen, testicles, etc., uni- ted with sodium chlorid ; the product corresponds in activity to 10 times its weight of the fresh tissue matter of the particular organ, the product being free- ly soluble in water and very diffusible. Oophorin. This is a dry preparation of the ova- ries of pigs and cows. It is put up in 5-grain tablets, and is used in female disorders, chlorosis, etc : Opnol. This is a solution of periplocin, the glucoside from the bark of Periploca gracea, with glycerin and small amounts PROPRIETARY AND SYNTHETIC REMEDIES. 809 of sodium iodid, menthol, pyridin, etc. It is used in asthma and heart diseases as a spray. — Pharm. Ztg. Orangeine. Each 5-grain powder is stated to con- tain 2 4/10 grains of acetanilid, 1 grain of sodium bicarbonate, 6/10 grain of caffeine and 1 grain of homeopathic trit- uration of blue flag, mandrake and nux vomica. Orchidin. This is liquid extract of bulls' testicles, which is employed hypodermically. Orchipin. This is an oily extract of bulls' testi- cles. It has been recommended as an antidote for atropine poisoning and as a nerve tonic in nervous debility and neur- asthenia. Oresol. This is the monoglycerinic ether of guaiacol. It is soluble in 40 parts of water and is very soluble in alcohol. It is said to be non-irritating to the stom- ach, it not being decomposed until it reaches the intestines. It is applicable in all cases where guaiacol or creosote is indicated. Orexine Hydrochlorid. (Phenyldi- hydroquinazoline Hydrochlorid.) This is in colorless, odorless crystals of a bitter, pungent taste, freely soluble in hot water and in alcohol. It was used for anorexia (lack of appetite) in doses of 2 to 8 grains. It is now superseded by the tannate, which see. Orexine Tannate. This is a yellowish, odorless, practical- ly tasteless powder, insoluble in water, very slightly soluble in alcohol, readily so in hydrochloric acid. It is used for anorexia (loss of appetite not due any lesion of the stomach) in doses of 4 to 8 grains 1 or 2 hours before the princi- pal meals. It is also useful for seasick- ness and vomiting of pregnancy and that following narcosis. It is incompatible with iron compounds. Orexoids. This is the name given 4-grain tablets of orexine tannate. Oriental Cream. See Gouraud's Oriental Cream. Orphol. (Bismuth Betanaphtholate — Betanaphthol Bismuth.) This is a brown, almost odorless and tasteless, non-caustic, non-irritating pow- der, insoluble in water, and containing 80% of bismuth oxid and 20% of beta- naphthol. It is partly decomposed in the stomach and entirely so in the intestines. It exerts an astringent and antiseptic ac- tion along the intestinal tract, and has the advantage of being entirely non- toxic. It is therefore used for summer diarrheas, typhoid fever, dysentery, gas- tritis, etc. The dose is 5 to 15 grains 3 times daily. Orthoform-New. This is the methyl ester of metamido- paraoxybenzoic acid. It is a fine, white, crystalline powder, odorless and taste- less. It is only sparingly soluble in water but soluble in 5 or 6 parts of alcohol. It is decomposed by boiling with water or by warming with alkalies or their car- bonates. It is a local anesthetic, resem- bling cocaine in its local action but not penetrating the tissues on account of its insolubility. It is somewhat antiseptic and practically non-toxic in the usual doses. It is used~internally to relieve the pain of gastric ulcer. It has been ap- plied locally as an analgesic to wounds of every kind, including burns and ulcers. It has been used in dentistry, in nasal catarrh, hay fever, etc. Internally the dose is 8 to 15 grains. Externally it is used as a dusting powder, or applied as an ethereal solution or oily mixture or in ointment form. Orthoform-New Hydrochlorid. This is the hydrochlorid combination of orthoform. It is a white, crystalline powder, soluble in 10 parts of water. Its compatibilities, action, uses and dosage are the same as those of orthoform — new, which see. 810 THE STANDARD FORMULARY Osgood's Cholagogue. Quinine sulfate :...dr. 2 Fluid ext. of culver's root. .fl. dr. 2 Saturated tinct. of stillingia.fi. oz. 4 Fluid ext. of podophyllum, .fl.dr. 3 Oil of sassafras drops 10 Oil of wintergreen drops 10 New Orleans molasses, to make fl.oz. 8 — Kilner's Form. Osmic Acid. (Perosmic Acid — Os- mium Tetroxid.) What is commonly known as osmic acid is actually osmium tetroxid. It is in yellow hygroscopic needles, which melt at the temperature of the body and are of an intolerably pungent and suffo- cating odor. The vapor is extremely ir- ritating to mucous membranes. It is sol- uble in water, alcohol or ether. It is used as an antineuralgic, particularly in sciatica, and as antiepileptic. The dose is 1/64 grain, given several times daily. As an injection it is given in quantities of 1/20 to V& grain daily in 1% solution. Osmosum. (117) This is described as a combination of "aluminum, glycerin and phenol." It is recommended as an application in all cases of inflammation. It is also put up with picric acid and with salicylic acid. Ossalin. This is the name given to a fat pre- pared from fresh beef bone marrow. It is recommended as an ointment vehicle. Ouabain. This is the active principles of the plant that furnishes the African arrow poison. It strengthens the systolic ac- tion of the heart and increases the blood pressure. Ovadin. This is an extract of ovaries. Ovagal. This is a combination of gallic acid and albumin. It forms a loose powder which, when taken in teaspoonful doses on an empty stomach, stimulates the ap- petite and has a laxative effect. It is in- dicated in cholelithiasis, chronic consti- pation, hemorrhoids, and diabetes. Ovaraden. This is a tasteless and odorless pow- der consisting of the active substance of pigs' ovaries, 1 part representing 2 parts of fresh gland. It is used in dysmenor- rhea and neurasthenia in doses of 15 to 30 grains daily. It is put up in the pow- der form, also in 4-grain tablets. Ovariin. This is a powder, 1 part of which rep- resents 8 parts of fresh cow's ovary, be- ing the desiccated substance of the ovary. It is used in chlorosis, affections of the heart, and menstrual troubles. It is also put up in 3-grain tablets. The dose is 8 to 24 grains 3 times daily. Ovarine. This is the sterilized extract of pigs' ovaries. It is used in cases of ovarian derangement which are classed under functional disturbances. Ovaritone. (182a) Each teaspoonful is stated to contain Viburnum prunifolium gr. 8 Hydrastis canadensis gr. 5 Senecio aureus gr. 5 Passiflora incarnata gr. 4 Anemone Pulsatilla gr. 2 Elixir aromaticus, q. s. Ovaron. This is a preparation made by treating the active constituent of cow's ovaries with tannin so as to produce a substance which is not affected by the gastric juice but will be absorbed in the intestinal tract. Ovoferrin. (Iron Vitellin.) (18) This is a solution containing 5% of an artificial proteid combination of iron; it also contains 10% of alcohol and some aromatics. The liquid is of a reddish- brown color, little odor, and a flat, slight- ly aromatic and alcoholic taste. It is used for the same purposes as other or- ganic compounds of iron. Ovo-Maltine. This is a dry preparation of pure malt extract, fresh eggs, milk and cocoa, the starch of the latter having been con- verted into maltose. PROPRIETARY AND SYNTHETIC REMEDIES. 811 Ox-Gall Tablets, Compound. (70) Each tablet is stated to contain Inspissated ox-gall gr. 2 Extract of pancreas gr. 2 Extract of nux vomica gr. l /% Oxaphor. (Solution of Oxycamphor.) Oxycamphor is derived from camphor by replacing a hydrogen atom by a hy- droxyl group, and oxaphor is a 50% al- coholic solution of oxycamphor. The latter is a white, crystalline powder, sol- uble in about 50 of cold water, more sol- uble in warm water, and readily soluble in alcohol, ether or chloroform. Owing to the fact that it is decomposed on pro- longed exposure to the atmosphere, it is marketed only in the form of the 50% alcoholic solution. It is recommended as a substitute for morphine in respira- tory disorders, such as dyspnea, nervous asthma, emphysema and bronchitis in doses of 40 to 60 drops. Oxone. (174) This is understood to be a combination of the peroxids of the alkaline earths. On contact with water it liberates oxy- gen. dxycamphor. See Oxaphor. Oxy chlorine. (155) According to the manufacturers, this is "tetraborate of sodium and potassium combined with oxychlorid of boron." Oxychlorine Dusting Powder. This is stated to be composed of Oxychlorine 5% Tannic acid 1% Sugar of milk, rice powder, and "precipitated cellulose" 94% Oxydasin. This is a solution of 1 g. of vanadic acid in 2000 g. of water, also containing some glycerin. Oxydendron Compound, Fluid. (143) Each fluidram is stated to represent Corn silk, fresh gr. 8 Hydrangea gr. 8 Queen-of-the-meadow gr. 8 Haircap moss gr. 8 Juniper berries gr. 6 Water eryngo gr. 4 Sourwood leaves gr. 1 Lithium benzoate gr. 3 Aromatics, q. s. Oxygen Aquae. A colorless, odorless and tasteless li- quid found to be water. — A. B. Prescott. Oxygen, Compound. A colorless, aqueous solution of am- monium nitrate and lead nitrate, the two salts being in nearly equal proportions, and together forming about 3% of the solution. — A. B. Prescott. Oxygen, Compound, Green's. An aqueous solution of ammonium nitrate with a very little lead nitrate. —A. B. Prescott. Oxygen, Compound, Solid. This is ammonium nitrate. —A. B. Prescott. Oxygen, Compound, O'Leary's. Contains alcohol, chloroform, bitter almond oil, balsam of tolu and red color- ing matter. — A. B. Prescott. Oxynol. (24) This is given as the formula : Ichthyol part 1 Phenol part 1 Zinc peroxid parts 2 Alum, powder parts 3 Zinc oxid .parts 5 Menthol and aromatic oils. Petrolatum and stearin. Oxyntin. (70) This is represented to be an organic combination of hydrochloric acid with albumin, containing 5% by weight of ab- solute hydrochloric acid. It is readily miscible with water and is soluble in the gastric juice. Oxyphenacetine Salicylate. This occurs in glassy scales. It is used as an antipyretic and antirheumatic. Oxysparteine Hydrochlorid. A salt of an alkaloid obtained from sparteine. It is in colorless crystals, sol- uble in water and alcohol. It is a car- diac tonic, usually employed hypodermi- cally. For one injection, ^ to iK> grains. Uzalin. A disinfectant said to consist of a 812 THE STANDARD FORMULARY mixture of calcium, magnesium and iron sulfates, with caustic soda and mag- nesia. — Coblentz. Ozogen. (211) This is a 3% hydrogen peroxid. Ozolax. (157) These are tablets stated to represent "soc. aloes, ipecac, nux vomica, and hen- bane." Ozolypotol. (157) This is stated to represent eucalyptol, menthol, thymol, biborate and benzoate of sodium, formaldehyde, glycerin, and baptisia. Ozomoru. (157) This is stated to be made according to the formula of Dr. C. H. Whitman. Each fluidounce is stated to contain Cod liver oil (sterilized) dr. 4 Hypophosphites limeandsoda.gr. 10 Guaiacol m. 3 Pancreatin gr. 3 Glycerin per cent 15 Alcohol per cent 5 Water, Irish moss, each, q. s. "Ozone, to saturation." Ozomulsion. (156) On the wrapper the statement is made that this is an emulsion of cod liver oil, guaiacol, glycerin, and the hypophos- phites of lime and soda, also that it con- tains iH% of alcohol. On a circular it is stated that the following is the for- mula : Each fluidounce contains 50% of cod liver oil, 4 drops of guaiacol "thor- oughly ozonized." Ozonized Water. This is said to contain 1 or 2 parts of potassium permanganate dissolved in 500 parts of water. Ozotone. (Elixir Phosphorus et Strychnia Comp. (157) Each fluidram is stated to contain Free phosphorus gr. 1/100 Strychnia nitrate gr. 1/60 Tr. cinchona m. 3 Tr. gentian comp m. 1 Tr. matricaria m. y 2 Tr. calumba m. y 2 Absolute alcohol. Glycerin. Aromatics. P. P. P. This is said to contain the fluid ex- tracts of green poke-root, green prickly- ash bark, stillingia and sarsaparilla, with compound tincture of gentian, potassium iodid and simple syrup. Pads. Years ago it was quite common to wear medicated "pads" for the treat- ment of diseases. There were kidney pads and liver pads, also anti-constipa- tion pads and uterine pads. The follow- ing is an example of one of the latter : Podophyllum, powder av.oz. 3 Aloes, powder av.oz. y 2 Culver's root, powder av.oz. y 2 Cypripedium, powder av.oz. y 2 Comp. ext. of colocynth. .. .av.oz. y 2 Croton oil fl.dr. 1 Oil of sassafras fl.dr. 1 Mix and make into a pad which was directed to be worn just below the pit of the stomach. The following formula has been given for an uterine pad av.oz. av:oz. Blue cohosh . Witch-hazel . Cinchona Angelica .... Ergot Guaiac wood Oil of eucalyptus Oil of tansy.. Oil of lavender av.oz. av.oz. av.oz. av.oz. .fl.dr. .fl.dr. .fl.dr. Mix the drugs, reduce to moderately fine powder, incorporate the oils, and make into an oblong pad, which is to be worn over the lower part of the abdo- men. See also Holman's Liver Pad. The following formula has been given for a stomach pad : Bayberry av.oz. 1 Lupulin av.oz. 1 Sassafras bark ...av.oz. I Myrrh av.oz. 1 Wild ginger av.oz. y 2 Cypripedium av.oz. y 2 Capsicum gr. 60 Oil of fennel fl.dr. 2 Oil of clove fl.dr. 1 Mix the drugs, reduce to moderately fine powder, and incorporate the oils. Make into an oblong pad to wear over the stomach. PROPRIETARY AND SYNTHETIC REMEDIES. 813 The following is intended for a kid- ney pad: Black cohosh av.oz. I Gum benzoin av.oz. I Gum guaiac av.oz. I Juniper berries av.oz. I Queen-of-the-meadow av.oz. i Digitalis av.oz. 2 Oil of juniper fl.oz. i l / 2 Mix the drugs, reduce to moderately fine powder, incorporate the oil, and make into an oblong pad. Page's Plain Hypophosphites. This preparation is stated to contain in each fluidram 3 grains of calcium hypophosphite and 2 grains of sodium hypophosphite. Page's Compound Syrup of Hypo- phosphites. This is stated to contain calcium, so- dium and manganese hypophosphites, strychnine and quinine sulfates, and iron pyrophosphate. Pain Expeller. Tr. capsicum annuum 70.0 Oil of rosemary 2.0 Oil of clove 2.0 Oil of chamomile, volatile 0.15 Oil of lavender . . 0.5 Oil of lemon 0.5 Oil of neroli 0.5 Medicinal soap 0.5 Camphor 1.5 Spirit of peppermint 10.0 Comp. spirit of melissa 10.0 Ammonia water 8.0 Tincture of caramel, q. s. The latter is composed of equal parts of caramel, alcohol and water. — Pharm. Centralh. Paine's Celery Compound. This preparation is stated to contain celery seed, calisaya, cascara sagrada, senna, prickly ash bark, sarsaparilla, hops, ginger, dandelion, mandrake, black haw, gentian, chamomile, black cohosh, yellow dock, potassium nitrate, dilute phosphoric acid, glycerin and water. Palmetol Pills. See Pil. Palmetol. Palmettine HypopEbsphites. (207) This preparation is stated to contain in each fluidounce saw palmetto berries, fresh, 120 grains; lime hypophosphite, 1^2 grains; and iron, potash and man- ganese hypophosphites, each 1 grain. Palmetto Cordial. (Cordial Palmetto Comp.) (117) This is stated to contain the virtues of ripe berries of Serenaea serrulata and true Santalum album, each fluidram rep- resenting saw palmetto, 20 grains, san- dalwood, 10 grains, and aromatics. Palmetto Tonic. (148) This is stated to contain saw palmetto, sandalwood, couch grass, damiana, pichi, corn silk, and aromatics. Palmetto Suppositories. (148) These are vaginal suppositories, each one containing 10 grains of solid extract of saw palmetto combined with anti- septics. Palmiacol. (Cetiacol.) This is described chemically as cetyl- guaicyl. It is a liquid insoluble in water but soluble in alcohol, ether and chloro- form. It is said to have properties simi- lar to creosote and guaiacol and is used internally for tuberculosis and chronic bronchitis. It is put up in gelatin pearls containing 3 minims each. Palmo-Santal. See Palmothal. Palmothal. (142) This is stated to be a combination of the fresh berries of saw palmetto, fresh stigmata of corn silk, fresh rhizomes of couch grass, and santal. Palpebrine. (64) This is stated to contain as "active principles" boric acid, mercury bichlorid, tincture of opium, zinc sulfate, glycerin, and distilled and camphorated waters. Panase. (187) This is described as a combination of all the pancreatic enzymes in a highly active form. It is said to be capable of dissolving 200 times its weight of starch in 10 minutes. It is a light yellowish- white powder of a slight odor and a somewhat mucilaginous taste. It is mar- keted in the form of powder, 2-grain 814 THE STANDARD FORMULARY tablets, and an essence, each fluidram of which contains 2 x /> grains of the fer- ment. Pancreatin-Pepsin Comp. (108) This is stated to contain pepsin, pan- creatin, extract of nux vomica, ginger, bismuth subnitrate. and sodium bicar- bonate. It is put up in tablet form. Pancreatokinase. This is a mixture of pancreatin and eukinase. Pancreo-Bismuth. This is stated to contain pancreatin, bismuth, sodium bicarbonate and ginger. Pancreo-Digestin. See Elixir Pancreo-Digestin. Pancreo-Digestin Powder. (188) This is stated to contain ptyalin, pep- sin, pancreatin, and lactic and hydro- chloric acids. Pancreopepsine, Liquid. (212) This is stated to contain pancreatin, pepsin, and lactic and muriatic acids. Pancrobilin. (167) This is the formula as given by the manufacturers : Purified ox-bile gr. Y± Pure extract pancreas gr. 34 It is put up in the form of a liquid and pills. Pancrobilin Comp. Pills. These are put up in two forms called mild and strong. The mild form is stated to contain Ox-bile, inspissated gr. i Pancreatic extract gr. l /± Comp. ext. colocynth gr. % Quinine sulfate gr. l / 2 Extract taraxacum gr. ¥i The strong form differs only in con- taining ]/ 2 grain of extract of colocynth. Pancro-Pepsin. (181) This is stated to contain pancreatin, pepsin, vegetable ptyalin, lactic and hy- drochloric acids, and sugar of milk. Pancro-Pepsin Elixir. Each fluidram is stated to represent io grains of pancro-pepsin. It is also put in various combinations, such as with beef, iron and wine, with bismuth, with bismuth and strychnine, with gentian and iron chlorid, and with phosphate of iron, quinine and strych- nine. Pancro-Pepsin, Liquid. Each fluidounce is stated to represent 8o grains of pancro-pepsin. Panjecorine. (187) This is the name applied to the extract made from the fresh livers of the cod- fish. It is used in making the wine of cod liver oil. Pankreon. This is a compound of pancreatin with io% of tannin. It passes through the stomach, being able to resist gastric di- gestion. It is a grayish-red powder of a not unpleasant taste. It is insoluble in water and in dilute acids of the strength of the gastric juice. It is used in pan- creatic diabetes, intestinal indigestion, gastritis, apepsia, etc., in doses of jYz grains 3 times a day. Panopepton. (70) This is a description as given by the manufacturers : Content of alcohol by volume 19.7%, by weight 16% ; total dry solid, 22%; proteids (Xx6.25), 6.3%; carbohydrates, 13% ; inorganic salts (ash), 1%; free from cane sugar or chemical preservatives. It is said to be prepared from beef and wheat by diges- tion with gastric and pancreatic juices. The substance obtained by the digestion is mixed in fixed proportion of protein and carbohydrate, on the basis of actual assay, sterilized, concentrated in vacuo, and dissolved in fortified Spanish sherry wine. It is used as a liquid food. The dose for an adult is 2 to 4 teaspoonfuls several times a day and at bedtime ; for infants, from a few drops to 30 minims. Pan-Peptic Elixir. The manufacturers state that each dessertspoonful represents 1 pan-peptic tablet in solution. Pan-Peptic Tablets. (182a.) The composition as stated by the man- ufacturers is 1 grain each of pure pepsin PROPRIETARY AND SYNTHETIC REMEDIES. 815 and pure pancreatin, yi grain caffeine and q. s. each of acid lactophosphate of calcium and celery. Panzyme. (187) This is stated to be composed of vera diastase, pancreatin, pepsin, and rennin, with carminatives and aromatics. It is marketed in the tablet form. Papain. (Papayotin.) This is the concentrated ferment from the juice of the papaw fruit. It is an amorphous, whitish powder which is sol- uble in water and glycerin. It is employed as a digestive ferment. It digests albuminous matter, acting in acid, alkaline or neutral liquids. When given internally, the dose is 2 to 5 grains after meals. Papayans. (20) These are 5-grain tablets which are stated to contain the digestive principle of the fruit of Carica papayac, combined with willow charcoal, sodium bicarbon- ate, and aromatics. Papier Fayard. The following is the formula given in the expired foreign patent : Linseed oil parts 500 Turpentine , parts 500 Lead acetate parts 50 Garlic (chopped fine) parts 30 Yellow ochre parts 30 Red lead parts 15 Boil the garlic with the oil, stirring constantly, strain, and add the other sub- stances. The resulting compound is next spread on tissue paper, either with a sponge or a broad camel's hair pencil, such as is used by gilders, and allowed to dry at the- ordinary temperature, or in a heated room, for about two weeks. When the paper is dry, spread on it the following mixture : Olive oil . . parts 200 Yellow wax parts 6 Red lead parts 100 Another process is said to be carried out by making a tincture from 3 drams euphorbium, 6 drams cantharides, and alcohol 4 fluidounces, and dissolving in the filtered tincture 3 drams Venice tur- pentine. Fine tissue paper is dipped into this mixture and then dried. This paper is used as an application for rheumatism, gout, sprains, etc. Papillaud's Antimony Granules. These are pills weighing 0.1 g. which contain, according to Dorvault, antimony iodid, but according to Blaser are com- posed of antimony arsenate, 0.0005 ; tra- gacanth 0.01, and red colored sugar, 0.04. Parachlorsalol. (Parachlorphenol Salicylate.) This is in fine, white, almost tasteless and odorless needles, soluble in alcohol or ether, insoluble in water. It is used as an internal or external antiseptic like salol. Dose : 2 to 4 grams, 30 to 60 grains per day, in divided quantities. Paroform. (Paraformaldehyde — Trioxymethylene — Triformal.) (130) When formaldehyde in aqueous solu- tion is heated for a sufficient length of time a polymeric form is obtained in the form of a white, crystalline powder which is insoluble in water. This is known as paraform. It is used as an in- ternal antiseptic and astringent in chol- era, diarrhea, dysentery, etc., the dose being 8 to 15 grains ; for children Y^ to 1^2 grains every 2 hours. It is also used as a surgical dressing, for the genration of formaldehyde (by heating), and in dentistry for the disinfection of root canals. Paraganglia This is a preparation of the suprarenal bodies of Italian origin. It is supposed to be the serum of the medullary sub- stance of the suprarenal bodies. It is a clear, yellowish fluid of a sweetish taste. The dose is 5 to 10 drops several times daily. Paraldehyde. (Elaldehyde.) This is a colorless, transparent liquid of a strong characteristic odor and a burning taste. It is soluble in 8 parts of cold water, 16 parts of boiling water, but is n iscible in all proportions with alcohol, ether, fixed or volatile oils. It 816 THE STANDARD FORMULARY is used as a hypnotic in doses of 10 to 30 minims. It should be preserved in well-stoppered, amber-colored bottles in a cool place. Paraldehyde Elixir, Robinson's. See Robinson's Elixir Paraldehyde. Para-Lysol. This is stated to be a combination of potassium and cresols. Analysis showed 8.3% of the former and 91.7% of the latter, which corresponds to 1 molecule of potassium to 3 molecules of cresol. It crystallizes in non-hygroscopic, white needles but is marketed in tablets of about 1 gram each, which are packed in glass tubes. It is a mild, non-poisonous antiseptic. Paranephrin. (130) This is a substance obtained from suprarenal capsules without the aid of acids and alkalies and is entirely free from albumoses and peptones. It is a yellow, friable mass, soluble in water. It is supplied as a 1 :iooo solution in water, containing 0.6% of sodium chlorid. It is used as a hemostatic. Paraplast. This is a preparation devised by Unna and is similar to gutta percha mull. It consists of fine thick cotton web on which is spread a plaster mass of rub- ber, wool-fat, resin and dammar. The latter is medicated with zinc oxid, mer- cury, salicylic acid, chrysarobin, etc. Pararegulin. (96) This is an emulsionized mixture of liquid paraffin combined with 10% of aqueous extract of cascara. It is mar- keted in gelatin capsules each containing 3 grams of the emulsion. Paratoloid. See Tuberculin. Paraxin. Dimethylaminopara-xan- thin. (26) This is in white crystalline mass, slightly soluble in cold water, freely so in hot water. It is recommended as a diuretic. Parisol. This is described as a condensation product of formaldehyde ana saponified naphtho-quinones, which is recommend- ed as a non-toxic antiseptic and odorless disinfectant. Parsons' Local Anaesthetic. Chloroform parts 6 Tincture of aconite parts 6 Tincture of capsicum parts 2 Tincture of pyrethrum part 1 Oil of clove part 1 Camphor part 1 Dissolve the camphor in the chloro- form, add the oil of clove, and then the tinctures. — Dr. Parsons. Pas-Avena. This is stated to be a compound of passiflora, Avena sativa, and somnalge- sine. The latter is stated to be a new chemical of the formula C30 H 30 Ns 3 . Paskola. According to Dr. Eccles, this is simi- lar : Glucose syrup . . .' pound 1 Hydrochloric acid drops 50 Sulfurous acid, U. S. P., freshly prepared drops 6 or 8 Pasta Mack. This is stated by Ecksten to be com- posed of 2.7 parts of rice starch and 73 parts of effervescing powder (sodium bicarbonate, 10, tartaric acid, 9), per- fumed and made into tablets. This prep- aration is added to the water used for a bath when carbonic acid gas will be evolved. — Ph. Ztg. Pasteurine. (135) This is given as the formula : Oils of cassia, gaultheria and eucalyptus, men- thol, glycerin, 3/10% of formaldehyde, and saturated solution of boric acid. Pasteurine Anti-Constipation Tab- lets. These are stated to contain Salol Aloin gr. Resin of podophyllum gr. Y% Extract of belladonna leaves, .gr. % Oleoresin of capsicum gr. 1/40 Strychnine .gr. 1/80 Oils of cinnamon, peppermint and eucalyptus. gr. y 2 PROPRIETARY AND SYNTHETIC REMEDIES. 817 Patch's Exarysis Tablets. See Exarysis or Exhaustion Tablets. Patch's Leucogon Tablets. See Leucogon Tablets. Patterson's Pastilles. Bismuth subnitrate io.o Calcined magnesia io.o Sugar 90.0 Tragacanth 0.2 Orange flower water, to make 100 pastilles. — H. Patterson's Powder. Bismuth subnitrate 5.0 Calcined magnesia 5.0 Sugar 80.0 -H. Pautauberge's Solution. (210) Each tablespoonful is stated to contain 10 centigrams of creosote and 50 centi- grams of "hydrochloro-phosphate of lime." It is recommended for tubercu- losis, broncho-pulmonary affections, scro- fula, rickets, etc. Pava Pepsin Comp. (135) This is stated to be a combination of the digestive ferments with caffeine and pineapple juice. Peacock's Bromides. (Syr. Brom. Comp.) Each fluidram is stated to contain 15 grains of the combined bromids of po- tassium, sodium, calcium, ammonium, and lithium. Pectorin. This is a name given to pastilles con- taining potassium sulfoguaiacolate. Pediculin. This is a substance introduced in Ger- many as a remedy for lice and other similar parasites. It consists of 65% of powdered chalk and 35% of commercial naphthalin. Pegnin. (Milk Sugar Rennet.) This is prepared by mixing rennin, the milk-curdling enzyme of calf's rennet, with milk sugar and sodium chlorid. It is a fine white powder, readily soluble in water and forming a solution which co- agulates the casein of milk. It is used for the purpose of coagulating milk. Cow's milk so coagulated is said to be particularly serviceable for infant feed- ing and well adapted as a food for adults in stomach affections, being much more digestible than raw milk. 60 to 75 grains of pegnin are required for 1 pint of milk, which should previously have been boiled and cooled to about 40 C. The mixture, after brief shaking, should be allowed to stand for 2 or 3 minutes or until it is entirely coagulated, and then shaken for several minutes until the coagulum has been converted into a smooth, homogeneous mixture, and set aside in a cool place. It is then to be transferred to the nursing bottle as re- quired and heated in warm wat^r to the body temperature (about 38 C.) before feeding to infants. Pelagin. A remedy for seasickness said to be a solution of antipyrine, caffeine and co- caine. Peleg White's Salve. See White's Salve. Pelletierine Tannate. (Punicine Tan- nate.) This is a light yellow, odorless, amor- phous powder of an astringent taste. It is soluble in 235 parts of water, 13 of alcohol at 25 C. and in warm diluted acids but is insoluble in chloroform. It should be kept in small, well-stoppered, dark amber-colored bottles. It is as an anthelmintic, especially for tapeworms. It is given in doses of 3 to 8 grains in an ounce of water, which are to be followed in a half hour by a cathartic. Pellotine Hydrochlorid. This is an alkaloidal salt derived from Anhalonium Williamsi, a Mexican cac- tus. It is in colorless crystals which are soluble in water and slightly soluble in alcohol. It is used as a hypnotic in closes of 1 to V/2 grains. Pemzed. This is described as an infant food consisting of pure- milk sugar with the addition of small amounts of calcium hypophosphite and sodium chlorid. 818 THE STANDARD FORMULARY Penne's Liqueur Antiseptique. Carbolic acid parts 4 Hydrobromic acid part 1 Diluted alcohol parts 100 It is used against the stings of insects and bites of animals. — H. Penne Suppositories. These contain 1 to 2 grains of picratol with boroglyceride and glyco-gelatin. — Pharm. Centralh. Pental. (Trimethylethylene — Betai- soamylene.) This is a colorless liquid soluble in all proportions of alcohol, ether and chloro- form, but insoluble in water. Employed as an anesthetic in minor surgery, such as extracting teeth, etc. Dose : Inhalation, 3 to 5 drams. Penoform. This is a German snuff whose chief ingredient is the suprarenol gland. It is used for hay fever and in the various forms of coryza. Pepdilactic Elixir. This elixir is said f,o be a palatable form of pepdilactine (which see). Pepdilactine. (198) The synonym given by the manufac- turers is "compound pepsin powder." It is described as containing pepsin, ptyalin, pancreatin and lactic and hydrochloric acids. Pepsin and Wafer Ash. The following makes a suitable prepa- ration of this kind : Pepsin, pure gr. 128 Fluid extract of wafer ash.fl.oz. 2 Glycerin fl.oz. 8 Water, to make fl.oz. 16 Mix the pepsin with the glycerin and 6 fluidounces of water ; agitate occasion- ally until the pepsin is dissolved ; mix with the fluid extract, set aside for a day or so, and filter clear. Pepsin Cordial. (159) Each fluidram is stated to digest 3000 grains of coagulated and disintegrated egg albumin. Pepsol. This is stated to be a combination of one of the coal tar derivatives, phenolid, combined with pepsin and sodium bicar- bonate. Elsewhere in this work, pheno- lid is stated to consist of acetanilid and sodium salicylate. Pepso-Ptelea. (Pepsin and Wafer Ash.) (17) This is stated to contain glycerin, but no spirit. See Pepsin and Wafer Ash, which contains pepsin, wafer ash and glycerin. Peptenzyme. (167) This is the process or formula given by the makers : We take 1000 each of the following glands : Salivary, peptic, pancreatic, Lie- berkuhn's and Brunner's, and the alco- holic extract of 1000 spleens and livers, so that any quantity of it, either 1 pound or 1 grain, contains a proportional quan- tity of the enzyme principles of the whole series of digestive organs. To 6 parts of this isolated protoplasmic, ac- tive and latent enzyme mixture in pow- dered form and slightly benzoated, and separated mechanically as described above, add 9 parts of powdered sugar, 9 parts of powdered milk sugar, 1 part of citric acid. Peptenzyme Elixir. This is stated to contain 16.14% by volume or 13.08% by weight of alcohol, also nucleo-enzymes of the salivary, peptic and intestinal glands, of the pan- creas and of the spleen. Pepto-Brom-Eigon. This is one of the eigons (which see) and contains 11% of bromin. It is a whitish powder soluble in water. It is used in place of the bromids. The dose is the same as that of potassium bromid. Pepto-Fer du Dr. Jaillet. This is said to have for its basis an organic compound of iron, chloropep- tonate of iron, a combination of pep- tone and perchlorid of iron, a neutral salt, and entirely dialyzable. PROPRIETARY AND SYNTHETIC REMEDIES. 819 Pepto-Iodo-Eigon. This is a yellowish, odorless, almost tasteless powder, soluble in water, and contains 15% of iodin. It is one of the eigons (which see). It is intended as a substitute for the iodids and is given in the same doses. Pepto-Mangan, Gude's. (Liquor Mangano-Ferri Peptonatus.)^ Each tablespoonful is stated to con- tain the equivalent of 3 grains of metal- lic iron and 1 grain of metallic manga- nese. It is used for anemia, chlorosis, etc. Peptonic Pills. (221) These are compressed tablets, weigh- ing nearly 5 grains. They are stated to contain I grain of pure pepsin, 1 grain of pure pancreatin, and lacto-phosphate of lime and lactic acid. Peptonized Glycerophosphates. (141) Each fluidounce is stated to contain Calcium glycerophosphate ...gr. 6 Magnesium glycerophosphate.gr. 2 Potassium glycerophosphatc.gr. 2 Sodium glycerophosphate. .. .gr. 2 Iron glycerophosphate gr. I Tincture of nux vomica m. 1 Pepsin gr. 8 Fresh kola nut gr. 12 Peptopancreatine Compound Powder. (192) This is stated to contain pepsin, pan- creatin, ptyalin, diastase, and lactic and hydrochloric acids. Peptopancreatine Compound Elixir. Each fluidounce is stated to contain 40 grains of peptopancreatine com- pound. Pepule Lecibrin. (70) These are stated to present the com- plex, organic, phosphorized-fat constitu- ent of the brain in combination with nucleo-proteids. Pepule Pancro Hepatic. (70) Each one is stated to contain 3 grains of extractum pancreatis and 1 grain of inspissated ox-gall. Perborate of Sodium. (NaB0 3 , 4 H,0.) This is a white powder which when dissolved in water at once produces hy- 52 drogen peroxid. It is non-toxic and non-irritant, antiseptic and mildly as- tringent, and is applicable in powder form for insufflation. It is also said to be adapted for treatment of diseases of the eye, ear and throat. Percoll. This is a form of adhesive plaster in which the adhesive is applied to parch- ment instead of linen or muslin. When applying this plaster the back surface is to be moistened with water to give it the required pliability. On drying the plaster becomes stiff again. Percutilan. See Prsevalidin. Perdynamin. This is an iron preparation said to contain iron in the form of hemoglobin combined with albumen. It is used as a nutritive. Perglutyl. This is described as a solid form of hydrogen peroxid, obtained by dissolv- ing gelatin, with more or less glycerin, in hydrogen peroxid, with the aid of a gentle heat, to afford a solid mass on cooling. The quantity of gelatin and glycerin may be varied so as to form a soft mass or a hard one which may be reduced to powder. The preparation is intended for use internally and exter- nally in all cases where the antiseptic and disinfectant properties of hydrogen peroxid are required. — Ph. Ztg. Perhydrol. (130) This is described as a 30% solution of hydrogen dioxid which is free from acid. The advantage claimed for this preparation is less irritating on account of the absence of acid. By suitable di- lution a preparation is obtained equiva- lent to the official solution of hydrogen peroxid. Peristaltic Pills. (212) These are stated to contain each Aloin gr. 1/4 Extract of belladonna gr. 1/8 Ipecac gr. 1/16 Strychnine gr. 1/60 820 HE STANDARD FORMULARY Peristaltic Aperient Fills are said to contain each Aloin gr. i/io Belladonna juice gr. 1/20 Ipecac gr. 1/30 Strychnine sulfate gr. 1/100 Peristaltic Comp. Pills contain each Salol gr. 2 Ingluvin gr. 1/2 Strychnine sulfate gr. 1/100 Aloin gr. 1/10 Ext. belladonna gr. 1/30 Peristaltic Mercurial Pills contain each Aloin gr. 1/4 Ext. belladonna gr. 1/8 Strychnine gr. 1/60 Ipecac gr. 1/16 Calomel gr. 1/10 Peronine. (Benzylmorphine Hydro- chlorid.) This is a bulky white powder, bitter in taste, which is freely soluble in water and diluted alcohol. This substance is a narcotic, being allied to morphine and codeine. It is supposed to be safer than morphine and more effective than codeine. It is used like morphine and codeine to induce sleep, to relieve pain and the coughing accompanying bronchitis and phthisis. It is given in doses of Y\ to ^ grain. The maximum single dose is 1 grain, the maximum daily dose, 4 grains. Peroxoles. The peroxoles are the class of prepa- rations represented by camphoroxol, menthoxol and thymoxol, which see. Perry's Moth & Freckle Lotion. According to Chandler's analysis, 1 fluidounce of this liquid contains 2.67 grains of mercury and 0.99 grains of zinc (corresponding to 3.61 grains of corrosive sublimate and 4.25 grains of crystal zinc sulfate). The sediment con- tains small amounts of mercury, lead and bismuth. Persodine. This is a name applied to a solution of persulfates, chiefly sodium persulfate. Personne's Iodized Oil. Dissolve 1 gram of iodin in 200 grams of sweet almond oil. — H. Perugen. This is a synthetic substitute for peru balsam, containing 60% of cinnamein. Peruol. This is a name given to a 25% solu- tion of benzoic acid benzylester, dis- solved in castor oil. This ester is said to be the therapeutically active constitu- ent of peru balsam. The liquid is color- less, odorless and non-irritant, and is recommended as a substitute • for peru balsam in scabies and other affections of the skin. Peruscabin. This is a name given to pure benzoic acid-benzyl ester, the principal therapeu- tic constituent of peru balsam. Peters' Peptic Essence Comp. This is stated to contain pure pepsin, pure pancreatin, pure diastase, and pure lactic and hydrochloric acids preserved in solution with glycerin, and made pal- atable by the addition of aromatics; it is said not to contain alcohol or sugar, and that 1 fluidounce will digest 3000 parts of coagulated albumen. Petro-Coco. (194) This is described as a specially re- fined form of petroleum, to which choc- olate has been added. It is advocated as a nutritive to replace cod liver oil emulsions. Petrogen. (221) This is described by the manufactur- ers as a modified mineral oil. It is put up in combination with camphor, car- bolic acid, creosotee, guaiacol, ichthyol, iodin, iodoform, and menthol. Petrol. (198) The synonym given by the manufac- turers is "petrolatum." This is also the European name for gasoline. Petrol Oil. (198) The synonym given by the manufac- turers is "petrolatum oil." Petrolan. This is the name for a new ointment base, a combination of mineral oils with soaps, etc. PROPRIETARY AND SYNTHETIC REMEDIES. 821 Petrole-Alba. (94) This is described as a colorless, odor- less and tasteless oil from pure Russian petroleum. Petrole-Alba Comp. This is stated to contain camphor, menthol, eucalyptol, hydrastine hydro- chlcrid, and oil of gaultheria with pet- role-alba. Petrolene. (181) This is described as a purej colorless hydrocarbon oil. Petroleum Compound Emulsion. (182a) Each fluidounce is stated to contain 33^3% of refined petrolatum oil and io grains of the combined hypophosphites of calcium and sodium. Petrolatum Compound Pills. (212) These pills are stated to contain each Petroleum gr. I Tar gr. I Magnesium carbonate gr. 1/2 Strychnine sulfate gr. 1/100 Oil of wintergreen m. 1/20 Petrosulfol. See Ichthyolum Austriacum. Petrox. This is the saponated petrolatum of the N. F. It is in two forms, a solid and a liquid. The latter may be com- bined with iodin, carbolic acid and many other remedies applied externally. Peptic Digestant. This is stated to be "composed of pep- sin, pancreatin, diastase, hydrochloric and lactic acids, combined with an aro- matic vehicle." Phagocytin. This is a sterilized solution of sodium nucleinate intended for hypodermic use in the treatment of lowered conditions of the nervous system. Each cc. is stat- ed to contain 0.05 gm. of salt. Phalon's Vitalia. According to Chandler's analysis, this consists of two liquids, the one being a solution of sodium hyposulfite, the other a clear, reddish liquid containing about 3% of lead.— H. Pharyngine. This is a preparation containing thy- mol and eucalyptol used as a gargle in catarrhal affections, etc. Phaselin. (4) This is described as the principle de- rived from Dolikos mexicana, a Mexi- can bean. It is recommended as an aid to digestion. It is put up in powder and tablet forms. Phenacetin. (Paracetphenetidine — Phenetidine.) This is a colorless, tasteless crystalline powder, very sparingly soluble in water, soluble in 16 parts of alcohol. It is em- ployed as an antipyretic and antineu ralgic, in doses of 8 to 15 grains. Used for catarrhs, colds, influenza, etc. This compound is of special interest because it is the base or nucleus of many other synthetic compounds which are used medicinally such as kryofin, cit- rophen, pyramidon, lactophenin, triphe- nin, apolysin, phenocoll, etc. Phenaceto-Caffeine. (212) This is a granular effervescent salt, each dessertspoonful of which is stated to contain 5 grains of sodium bromid, 3 grains of phenacetine, and 1 grain each of caffeine and celery. Phenalin. This is one of the various names ap- plied to phenolphthalein. It is put up in tablets of 0.05 g. each. Phenanmine. Same as Phenocoll Hydrochlorid, which see. Phenartol. (76) This is described as a combination of phenol with benzartol (which see). Phenatol. This is said to be a mixture of ace- tanilid, caffeine, and sodium bicarbonate, carbonate, sulfate and chlorid. — Cob- lentz. Phenazone. This is a name for antipyrin. 822 THE STANDARD FORMULARY Phenocoll Hydrochlorid. (Amido- acetphenetidin Hydrochlorid — Phenamine.) (178) This is the hydrochlorid of a synthetic base obtained by the combination of phenetidin and glycocoll. It differs from phenacetin in that one hydrogen atom of the acetyl group has been replaced by N H 2 . It is a white microcrystalline powder, soluble in 16 parts of water at the ordinary temperature, very soluble in hot water and alcohol. It is incom- patible with soluble hydroxids or car- bonates. It is similar to phenacetin in its effects and acts an antipyretic. It is also used in rheumatic fever. The dose is 5 to 25 grains dissolved in water be- fore taking; hypodermically the dose is 4 to 8 grains. Phenocoll Salicylate. See Salocoll. Phenol-Bismuth. (Bismuth Carbo- late.) This is a white, non-toxic, non-caustic powder, almost devoid of odor and taste, containing 80% of bismuth oxid and 20% of phenol in combination. It is recommended as an antiseptic in gastro- intestinal gastritis, dysentery, typhoid fever, etc. The dose is 15 to 75 grains daily. Phenol Camphor. (Camphorated Phenol.) Camphor and crystal carbolic acid, when mixed, form an oily liquid, which does not possess the caustic properties of carbolic acid. The mixture is made preferably with 3 parts of camphor to 1 of acid by weight. The product is in- soluble in water, but soluble in alcohol, ether, chloroform and oils. It is a use- ful antiseptic and disinfectant. Phenol Sulforicinate. This is a thin, aqueous or a syrupy and viscid liquid (according to different methods of manufacture), yellowish in color, of ethereal odor, and soluble in water and alcohol. It is used in solu- tions of 20 to 30% strength as an appli- cation in diseases of the nose and throat Phenolid. According to analysis, this has been shown to be a mixture of acetanilid, 58 parts, and sodium salicylate, 43 parts, or approximately : Acetanilid parts 4 Sodium salicylate parts 3 — Pharm. Rdsch Phenolphthalein. This is a crystalline or amorphous powder, white or grayish white, soluble in 600 parts of water and in 10 of alco- hol. It is used in medicine as a purga- tive, the adult dose being V/2 to 3 grains, although as much as 8 grains may be given with safety. It is of special in- terest at present because it is the basis of many proprietary or semi-proprietary laxative pills and tablets. Phenosalyl. Carbolic acid parts 90 Lactic acid parts 20 Salicylic acid parts 10 Menthol part 1 Mix by fusing acid and adding other ingredients. Phenthol. (154) This is an antiseptic and deodorant stated to contain 95% of pure phenol. Phenylacetamide. Same as Acetanilid, which see. Phenylacetic Acid. This is in white, shining laminae which are soluble in alcohol, ether and hot wa- ter. It is recommended as an internal antis'eptic and antitubercular. The dose is 10 drops, gradually increased to 20, of a 1 to 6 alcoholic solution, 3 times daily in water. Phenosal. (Phenetidin Aceto-Salicy- late.) This is in small colorless crystals of a sour taste and sparingly soluble in wa- ter, alcohol and ether. It is used as an antipyretic and antirheumatic in doses of 8 grains. Phenyo-Caffein. The manufacturers' circular states that the principal ingredients of these pills, or "sugar-coated powders," are phenylactamid (acetanilid), 2 grains, caffein and camphor. PROPRIETARY AND SYNTHETIC REMEDIES. 823 Phesin. This is a sulfo derivative of phenace- tin. It is a brown powder of a saline taste, readily soluble in water. Its prop- erties are about the same as those of phenacetin. The dose is 8 to 15 grains. Phillip's Emulsion. This is the formula given : Cod liver oil 50% Wheat phosphates . . . . . . 25% Glycerin, mucilage, pancreatin, sugar and water. Phonozyme. This is a name given by Dr. T. O. Summers to this mixture : Peptenzyme gr. 60 Boric acid gr. 30 Glycerin fl.dr. 4 Bitter almond water fl.oz. 3^2 Phorxal. This is a nutritive preparation derived from ox-blood and containing iron and phosphorus. It is an odorless and taste- less powder, soluble in aqueous liquids, and given in doses of K to 1 ounce daily in soup, milk, cocoa, etc. Phosote or Phosphote. (Tricreosote Phosphate.) This is a nearly colorless, syrupy li- quid, of a faint odor and taste of creo- sote. It contains 80% of creosote and 20% of phosphoric anhydride. It is rec- ommended for tuberculosis in place of creosote, in doses of 15 to 45 minims daily. Sometimes it is used hypodermi- cally. Phos. Tincture Cinchona Compound. This is said to contain in every 10 minims 1 minim each of tinctures of nux vomica, ignatia and matricaria; 4 minims of tincture of cinchona, >2 minim each of tinctures of gentian and columbo ; 2 minims of aromatics, and 1/300 grain of tr. phos. (c. p.). Phosphatic Emulsion of Cod Liver Oil.) (160) Each tablespoonful is stated to con- tain 50% by volume of cod liver oil, about 1Y5 grains of free absolute phos- phoric add, % grain of calcium hypo- phosphite, arid l A grain each of sodium and potassium hypophosphites and iron lactate. Phospherrin. A mixture of ferric chlorid, phos- phoric acid and glycerin. — Coblentz. Phospho-Albumen, Special Formu- la No. 33. This is the composition as given by the manufacturers : Phospho -albumen (ext. testes, spinal cord and brain, containing phos- phorized albumen, leci- thin, spermine, nuclein) . . .gr. 3 Strychnine sulfate gr. 1/50 Zinc phosphid gr. 1/10 Gold chlorid gr. 1/60 It is recommended as an aphrodisiac. Phospho-Caffein Comp. Each dessertspoonful is stated to con- tain Caffeine gr. l A Phosphoric acid gr. Vz Ext. celery seed gr. 1 Antipyrin gr. 1 Sodium bromid gr. 7 Phospho-Glycerate of Lime. See Chapoteaut's Phospho-Glycerate of Lime. Phospho-Lecithin. (211) Each dessertspoonful is stated to con- tain Lecithin gr. % Sodium glycerophosphate . .gr. 2 Calcium glycerophosphate, .gr. I Potassium glycerophos- phate gr. 1 Strychnine glycerophos- phate gr. 1/250 Glycerophosphoric acid, q. s. Avenine gr. 1/150 Phospho-Muriate of Quinine Com- pound. According to the manufacturers, this is a combination of the "wheat phos- phates" with strychnia and muriate of quinine. The formula is given thus : Each fluidram'contains 1Y4 grains of potassa, 1 grain of magnesia, ^4 grain of lime, 1 grain of iron, all in the form of phosphates; l /\ grain of quinine mu- riate, 1/120 grain of strychnine. 2 grains of free phosphoric acid, and simple syrup, q. s. 824 THE STANDARD FORMULARY Phospho-Neurine. (97) Each fluidram is stated to contain Phosphorus gr. 1/200 Arsenous acid gr. 1/80 Ext. nux vomica gr. 1/8 Hydriodic acid gr. 1 Ext. coca leaves (green) .. .gr. 6 With the "diastasic ferment" and or- ganic phosphates from the cereals. Phosphoric Elixir. See Robinson's Phosphoric Elixir. Phosphorus Mixture Comp. See Mixture Phosphorus Comp. Phosphotal. (Creosote Phosphite.) (77) This is a thick, yellowish, oily liquid, of the odor and taste of creosote. It is soluble in alcohol, chloroform and oils, and contains 90% of creosote. It is used in place of the latter on account of being more readily borne by the stom ach. The dose is 3 to 15 minims 3 times a day. Phthisocan. This is a syrup containing potassium guaiacol-sulfonate, flavored with orange. Phthisopyrin. Tablets have been put on the market under this name. They are stated to consist of \ x /l grains of aspirin, V/2. to 3 grains of camphoric acid, and 1/120 grain of arsenous acid. They are rec- ommended for tuberculosis, hence the name. Physol. This is the name given by Wilbert to a preparation used as a physiological solvent on wounds : Pepsin 100 Menthol I Eucalyptol I Oil of wintergreen I Alcohol 20 Diluted hydrochloric acid 40 Glycerin loo Distilled water, to make 2000 Physostigmine. See Eserine. Phytoline. (209) This is stated to contain the active principle of the berries of Phytolacca decandra. The berries should have been touched by the early frost, and be ex- tracted with diluted alcohol. The prod- uct contains 22>V2 c /o of alcohol. Picratol. (Silver Picrate or Trini- trophenolate.) (221) This is a yellow powder stated to con- tain 30% of silver, and soluble in 50 parts of water and 60 of alcohol, also soluble in glycerin. It is used like the other organic silver compounds for the treatment of gonorrhea and allied dis- eases, in y 2 to 2% solutions. It is also made up in vaginal suppositories con- taining 1 or 2 grains each and urethral suppositories containing ^ to 1 grain each. Picric Acid. (Trinitrophenol.) This is prepared by acting upon car- bolic acid with nitric acid. It is in yel- low crystals which are odorless, very bitter in taste, sparingly soluble in wa- ter, more soluble in alcohol. It is not used internally, but has been highly rec- ommended externally in aqueous solu- tion as an application for burns. It is incompatible with alkaloids and must not be combined with morphine sulfate, cocaine hydrochlorid, etc. Picrol. This is chemically potassium diiodore- sorcinmonosulfonate, and rs analagous to sozoiodol. It is a white, odorless powder, soluble in water, alcohol, ether and glycerin. It contains 53% of iodin, and is recommended as a non-toxic sub- stitute for iodoform. Pierce's Golden Medical Discovery. This is stated by the manufacturers to contain golden seal root, stillingia root, stone root, wjld cherry bark, bloodroot, mandrake root, glycerin, water, and bor- ate of soda (about 1 grain to the dose). Pierlot's Liquid Valerianate of Am- monia. Extract of valerian 2.0 Valerianic acid 3.0 Distilled water 950 Ammonium carbonate 1.0 or q. s. — H. PROPRIETARY AND SYNTHETIC REMEDIES. 825 Pierre's Eau Dentifrice. Make a tincture of 15 g. star anise and 200 of alcohol, add 50 drops each of the oils of star anise and peppermint and color with aniline red. — H. Pil. Aphro. (Aphrodisiac Pills.) (117) This is stated to be a combination of damiana, phosphorus and nux vomica. Pil. Hypo-Quinidol. (78) This is described as a soluble com- bination of quinine and "oxidizable phosphorus." Pil. Orientalis. This is stated to contain Ambrosia orientalis gr. 2 Extract saw palmetto gr. 1/4 Zinc phosphid gr. 1/30 Strychnos ignatia gr. 1/40 Strychnine nitrate gr. 1/450 With capsicum and aromatic powder. Pit Palmetol. (117) Each pill is stated to represent 30 grains of saw palmetto berries. Pine and Somnos Cordial. (141) Each teaspoonful is stated to contain the equivalent of 1 dram of white pine comp. with eucalyptol honey, 15 minims of somnos, and 1 grain of the com- bined glycerophosphates of lime, sodium and potassium. It is sedative and ex- pectorant. Pineoline. (209) This remedy for skin diseases is stat- ed to be prepared from the ethered ex- tract of the needles of the pine (pinus pumilio) incorporated with lanoline and white petrolatum. Pineoline. (217) This is described as an "antiseptic menthol oil solution containing menthol, eucalyptol, oleum dacrydium cupressium, camphor, cinnamon, and refined liquid petroleum." Pinus Alba Compound. (94) Each fluidram is stated to represent 4 grains each of white pine and wild cherry barks, 3 grains each of squill and senega, 2 grains of ipecac, 1 grain of blood root, 24 minims of paregoric, Y\ minim each of chloroform and oil of wintergreen and syrup, q. s. Piperazine. (Diethylenediamine — Pi- peraziline.) This is a synthetically prepared com- pound. It is in colorless, lustrous cry- stals which melt at 44 C. It is very soluble in water, less soluble in alcohol. It forms very soluble salts with acids; with uric acid it forms a salt soluble in 50 parts of water. It is incompatible with acetanilid, phenacetin, alkaloidal salts, nitrites, metallic salts in general, and picric and tannic acids. It should not be exposed to moisture. It also at- tracts carbon dioxid from the air. It has been recommended for the pre- vention of renal and visical calculi and for the relief of irritation of the bladder due to excess of uric acid in the urine and in cases of chronic gout, rheuma- tism, renal colic, etc. The dose is 5 to 10 grains ; daily dose, 15 to 30 grains. Piperazine Water. This is carbonated water containing piperazine and phenocoll. Piperidin-Guaiacolate. See Guaiaperol. Piperazine Monomethylarsinate. This is made by dissolving 1 molecu- lar weight of piperazine in cold 90% alcohol and adding to this a solution of 2 molecular weights of monomethylar- sinic acid in 90% alcohol. Piscin. This is a cod liver oil substitute used by homeopathic physicians in Germany. Pistoia Gout Powder. There is a powder made in a convent near Pistoria, Italy, and it is used very extensively as a protective against gout. The following is said by Chastaing to be its composition: Bryonia root g. 18 Gentian g. 18 Chamomile g. 10 Colchicum root g. 20 Betony g. 50 This is made into 365 powders, one of which is taken each day of the year in a full glass of cold or hot water. —Medical Record. 826 THE STANDARD FORMULARY Pittylene. This is described as a condensation product of pine tar and formaldehyde which forms a brown powder of a tarry odor. It is used in the treatment of chronic eczema. Pixine. This is stated to contain ichthyol, tar, turpentine and burgundy pitch, with wool fat. Plant's Asthma Cigarettes. These are said to consist of Stramonium leaves av.oz. 2 Green tea leaves av.oz. 2 Lobelia leaves av.oz. i}i Mix, moisten with a saturated aque- ous solution of potassium nitrate, and dry.— Ph. Post. Plasmon. This is a nutritive preparation made from casein. It is a yellowish, granular, sweetish powder, soluble in hot water. It is given in quantities of one or more teaspoonfuls several times daily. Plaster Mulls. These were devised by Unna and con- sist of plaster mass spread upon gutta percha tissue backed by mull. They are made in many medications, such as boric, carbolic, salicylic and pyrogallic acids, mercury, zinc oxid, ichthyol, re- sorcin, menthol, chrysarobin, etc. Plasticum. (181) This is Cataplasma Kaolini, U. S. P. Pneumin. (Methylene-Creosote.) This is a yellowish, odorless and tasteless powder, given in doses of 8 to 15 grains several times daily. It is used for the same purposes as creosote. Pleis' Fit Powders. Potassium bromid gr. 15 Gentian, powder gr. 5 Make 1 powder. — Drug Mill. Poehl's Physiologic Salt. This is a white powder, readily solu- ble in water. It contains all the osmoti- cally active constituents of blood serum and in the same proportions as they are contained in the latter. It is marketed in 1 g, tablets. It is used in V/2% solu- tion as a transfusion fluid. Pollantin. (Dunbar's Hay-Fever Serum.) (Schimmel.) This is an antitoxic serum obtained from horses treated with pollen toxin derived from ragweed. Horses are in- jected with gradually increased doses of pollen toxin (derived from ragweed) which results in the formation of an an- titoxin after 2 or 3 months of treat- ment. The horses are then bled and the strength of the serum is estimated by determining the proportion which will prevent the action of a solution of pollen toxin. The serum is preserved by the addition of X A% of phenol. It is a clear, slightly yellowish liquid which does not keep well when exposed to the air. When it becomes cloudy or devel- ops a bad odor, it should not be used. It is also put up in dry form. It is in- tended exclusively for use against hay fever, autumnal catarrh, rose fever, and June cold, and may be used as a pro- phylactic. One drop should be instilled into the outer angle of each eye and one or two drops into one nostril, the other being kept closed, in the morning be- fore arising. The liquid is more fre- quently used for the eyes, the powder form for the nose. Polyform. See Edison's Polyform. Polyformin. The insoluble kind is a combination of formin and resorcin. It is a yellow- ish brown powder, used externally as a substitute for iodoform. The soluble kind is a combination of two molecules of resorcin with one of hexamethylene- tetramine. Ponca Compound. Each tablet is said to contain 3 grains of extract of "ponca," 1 grain of ex- tract of mitchella, r A grain of caulophyl- lin, % grain of helonin, and ]/% grain of viburnin. Pond's Extract. This is described by the makers as a very pure and concentrated distillate of hamamelis. PROPRIETARY AND SYNTHETIC REMEDIES. 827 Pope's Cure for Neuralgia. Potassium iodid gr. 240 Extract of conium gr. 60 Comp. tincture cinchona. . .fl.oz. 2 Svrup sarsaparilla fl.oz. 4 —Nat. Dr. Pope's Sodium Salicylate Comp. Each tablespoonful is stated to con- lain Sodium sulfate gr. 122^ Sodium phosphate gr. 31 Sodium salicylate gr. 10 Strychnine sulfate gr. 1/120 Popium. This is described by the manufactur- ers as "the anodyne or pain-relieving principle of opium, the narcotic and convulsive elements being eliminated, each fluidram being equal in anodyne power to l A grain of morphia." Potassium Sozoidol. This is in colorless crystals soluble in 50 parts of water and in glycerin. It is a non-irritant antiseptic which may be applied to wounds, burns, skin dis- eases, etc., generally diluted with 10 to 20 parts of talcum or milk sugar. Aque- ous solutions darken on exposure to light. Potassium-Tonol. This is glycerophosphate of potas- sium. Potsdam Balsam. Oleobalsamic mixture fl.oz. 17 Comp. spirit angelica fl.oz. 2 Tincture of capsicum fl.dr. 3 Spirit of ammonia fl.dr. 5 — D. Powell's Aniseed Balsam. This has a composition similar to par- egoric. It has but little camphor, a small amount of rhubarb, and some ex- tract of licorice. — N. I. Praevalidin. (Percutilan.) This is a camphor ointment contain- ing 10% of camphor combined with peru balsam and eucalyptus and rose- mary oils. It is used by inunction in phthisis, chronic bronchitis, etc. Prescription 49. See "Boss, The/' Price's (Mrs.) Canning Compound. Investigation of a sample by the North Dakota Agricultural Experiment Sta- tion showed it to be boric acid. Prima Purificans. This is stated to contain cascara am- arga, burdock seed, poke root, prickly ash, wahoo, and sodium orthophosphate. Probilin Pills. (178) ' These are stated by the manufacturers to contain salicylic acid, acid sodium oleate, phenolphthalein, and menthol. They are recommended as a cholagogue, particularly in gall-stone disease. Proferrin. (Iron Nucleo-Proteid.) (141) This is a reddish brown powder insol- uble in water and acid solutions, soluble in alkalies with the production of a yel- lowish-red solution. It contains 10% of iron and 1% of phosphorus. It is ab- sorbed from the duodenum, being unaf- fected by the gastric juice. It is rec- ommended for all kinds of anemias in poorly nourished people. The dose is 5 grains 3 times daily. It is also put up in tablets of different sizes. Proferrin Comp. Tablets. These are stated to contain Proferrin gr. 3 Ext. cascara sagrada gr. 1/4 Extract of gentian gr. 1/4 Strontium arsenite gr. 1/60 Strychnine phosphate gr. 1/100 Proponal. This is described as an improved ver- onal, being dipropylbarbituric acid. It is in colorless crystals which are soluble in 70 parts of boiling water and 1640 parts of cold water. It is given in doses of 2^2 to 5 grains as a hypnotic. Propylamine. This is in clear crystals of an alkaline reaction, and having a strong odor re- sembling ammonia. It is used as a seda- tive and antispasmodic in doses of 3 to 10 grains. Prostaden. This is a saccharated extract from the prostate gland of steer, one part repre- 828 THE STANDARD FORMULARY senting two of fresh gland. It is used in gland hypertrophy, etc. Dose : 10 to 40 grains per day. Protalbin-Silver. This is an albumin compound of sil- ver. It is a grayish-white powder, solu- ble in about 10 parts of water and in glycerin. It is not precipitated by chlor- ids or albuminous compounds. It is rec- ommended as an injection in gonorrhea in J4 to i l A% solutions. Protan. (Tannin Nucleo-Proteid.) (141) This is a chemical compound contain- ing about 50% of tannin and is formed by the action of tannic acid on casein. It is a light brown, tasteless and odor- less powder, insoluble in water, acid solutions or the gastric juice. When in- jected it passes through the stomach undissolved, but becomes active when it reaches the alkaline pancreatic juice. It is highly recommended as an intest- inal astringent which may be taken in almost any dose. It is recommended for diarrheas of all kinds, typhoid fever, etc. The adult dose is 15 to 30 grains every hour or two ; for chil- dren the dose is 5 to 10 grains every hour. It is also put up in tablet form plain and in various combinations (with bismuth, opium, salol, etc.). Protan Comp. Tablets. Each tablet is stated to contain Protan gr. 2 Bismuth subnitrate gr. l /i Zinc sulfocarbol gr. % Pepsin gr. */$ Pancreatin gr. % Ginger gr. 1/16 Opium gr. 1/20 Guaiacol gr. 1/20 Calomel gr. 1/40 Oil of anise, q. s. Protargol. (Protein-Silver.) This is a compound of albumin and silver, containing 8.3% of the latter. It is an impalpable, yellowish-brown pow- der, soluble in twice its weight of cold water, producing a solution which is not affected by the ordinary precipitants of silver, salts, such as albumen, alkalies, sulfides, chlorids, bromids, iodids, nor by heat. It is precipitated by cocaine hydrochlorid but this is prevented by addition of boric acid. It is decom- posed by light. It is a non-irritant bac- tericide and antiseptic and is used most largely as an injection in gonorrhea. % to 1% solutions are recommended for acute gonorrhea, 5 to 10% instilla- tions in chronic gonorrhea, urethritis and cystitis, and 1 1200 to 1 :iooo solu- tions as irrigations. It may also be used in the form of tampons and boug- ies. It is also used in the treatment of diseases of the mucous membranes of the eye, ear, nose and throat. It is sometimes given internally in doses of 1 to 3 grains. Potassium-Tonol. This is glycerophosphate of potassium. Protogen. This is a combination of serum or egg albumin with formaldehyde. Its aqueous solution is not coagulated by heat. It is recommended as an addition to milk for feeding children. Protomiclein. (167) This is stated to be prepared from an equal number of pineal glands and pituitary bodies of the brain, salivary glands, thyreoid gland, pancreases, in- ner linings of stomachs, Brunner's glands and Lieberkuehn's follicles, and thymus glands, the whole preserved by an investment of benzoin and milk- sugar. The pineal glands and pituitary bodies are taken from the brain of the ox, the others from the pig. It is pre- pared in four forms : Powder, special powder, tablets, and suppositories. The tablets and powder are combined with milk-sugar. The special powder is for local and hypodermic use and consists of the pure nucleoalbumins unmixed with milk-sugar. Protosal. This is a salicylic ester of a glycerin- formaldehyde. It is a thickish liquid, soluble in ether, alcohol, chloroform and PROPRIETARY AND SYNTHETIC REMEDIES. 829 oils but insoluble in water and glycerin. It is used externally for rheumatism in mixtures containing 10 parts of pro- tosal, i of alcohol, and 9 of olive oil, by weight. Protozone. This is stated to contain thymol, so- dium benzoate, sodium salicylate, cit- rinol, glycerin and alcohol. Protylin. (Phosphorus-Albumin.) (98) This is an albumen preparation con- taining phosphorus, which is intended as a substitute for lecithin. It is a white, odorless, tasteless powder, containing 2.6% of phosphorus. It is insoluble in water but soluble in alkaline liquids. It is stated to be an assimilable, non- toxic form of phosphorus, useful as a nerve tonic and reconstructive in neu- rasthenia, rickets, scrofula, etc. The dose is 10 to 20 grains in soup, broth, etc., three times daily. It must not be boiled with food. It is also put up in combinations with arsenic, iron and bromin. Prunicodeine. (117) Each fluidram is stated to represent Wild cherry gr. 3 White pine gr. 2 Blood root gr. l / 2 Terpin hydrate gr. Yz Acetanilid gr x /z Codeine sulfate gr. y§ Pruni-Heroin. This is described as a compound syr- up of heroin and terpin hydrate. Pruni-Pepto. (214) Each iluidram is stated to represent Pepsin, pure gr. 2 Pancreatin gr. 1 Nux vomica f r y^ Lig. rennet • drops 10 . Combined with "celery fruit aro- matics." Prunier's Hyperphosphine. See Hyperphosphine. Pseudohyoscyamine. This is an alkaloid contained with hyoscine and hyoscyamine in duboisia leaves. It is in needle-shaped crystals of a yellowish color, which are spar- ingly soluble in water and ether, but freely soluble in alcohol and chloro- form. It has medical properties like hyoscine and hyoscyamine, but is less toxic. The dose is 1/32 to 1/20 grain, in subcutaneous injection. Pulsa-Flora. This is stated to contain in each fluid- ounce . Passiflora gr. 30 Pulsatilla gr. 15 Gelsemium gr. 15 Strontium bromid gr. 20 Aromatics, q. s. Pulvola. (165) This is stated to be sterate of cal- cium and magnesium. It is recommend- ed as an infant powder and as a dress- ing for wounds. Punicine Tannate. See Pelletierine Tannate. Purcell, Ladd & Co.'s Emulsion of Cod Liver Oil. The oil is stated to be emulsified with acacia; also each fluidounce is stated to contain 10 grains of the hypophos- phites of lime and soda, together with a small proportion of glycerin and alco- hol. Purgative Granules. The following is given as the com- position of each granule: Aloin gr. % Podophyllin gr. 1/16 Leptandrin . ..gr. 1/16 Judlandin gr. 1/16 Jalapin gr. 1/32 Oil of mustard drop 1/200 Oil of peppermint, q. s. Purgatin. (Purgatol — Anthrapur- purin Diacetate.) (109) This is the first synthetic purgative, being an oxyanthraquinone. It is a volu- minous orange-colored, crystalline pow- der, tasteless and insoluble in water and dilute acids, but slowly soluble in weak alkaline solutions, splitting off anthra- purpurin. It is incompatible with alka- lies and their carbonate. It is a laxa- tive and is said to be free from by-ef- 830 THE STANDARD FORMULARY fects. Being insoluble in dilute acids, it passes unchanged into the intestinal tract, where it is slowly split and pro- duces painless peristalsis. The dose is 5 to 20 grains. It is also put up in 5- grain tablets. Purgatol. See Purgatin. Purgo. This is a name given to phenolphtha- lein put up in tablet form. Purgerine. (Syrup Senna Aromat. Co.) (223) Tljis is stated to be made by extract- ing the cathartic principles from senna and jalap without extracting the bitter and griping properties. Puroform. This is stated to be composed of a zinc-formaldehyde compound, thymol, menthol and eucalyptol. It is recom- mended as an antiseptic and disinfect- ant. Pyohemol. This is made by dissolving cam- phoroform in carbolic acid. This is clear liquid, becoming discolored on ex- posure to light, of a disagreeable odor, and is soluble in alcohol, ether and oils. It is said to be antiseptic and hemostatic, and is also used as an in- halant in phthisis. Externally it is used in 10 to 20% mixture in ointments or with glycerin. Pyoktanin. This is the name given to two ani- line dyes, one violet, the other yellow, which have been used as antiseptics. Pyoluene. This is a name for oxymethylallyl- sulfocarbimide which is recommended as an antiseptic equal to mercuric chlorid. It is said to be very soluble in water, al- cohol, ether and glycerin, to be non- toxic, non-caustic, and to have an agree- able taste. Pyramidon. (Dimethylamidoanti- pyrin.) This is prepared by the reduction of nitroso-antipyrin to amido-antipyrin and treating this with methyl chlorid or iodid. It forms small, colorless cry- stals which are almost tasteless, solu- ble in 11 parts of cold water, 2 of alcohol and also soluble in ether. Its incompatibilities in general are the same as those of antipyrin. Oxidizing agents, also acacia, often produce colored solu- tions. It acts as an antipyretic and anal- gesic like antipyrin but is effective in smaller doses. It is claimed to be de- void of harmful influence on the blood, heart, or kidneys, in fact it is said to stimulate the heart's action. It has been recommended as an antipyretic in asthma, phthisis and abdominal typhus and as an anodyne in headaches and neu- ralgic pains, the dose being 8 to 12 grains. Pyramidon Camphorate. There are two forms of this com- pound, one being a neutral, the other an acid, salt of pyramidon and camphoric acid. Both are white, crystalline pow- ders, the neutral salt being soluble in 15 parts of water or 2 of alcohol, the acid in 20 parts of water or 4 of alco- hol. The salts combine the antipyretic action of pyramidon with the antihy- drotic action of camphoric acid. In the neutral salt the antipyretic action of the pyramidon predominates in the acid salt, the antihydrotic action of the cam- phoric acid. They are particularly rec- ommended in the febrile conditions of phthisis, attended by profuse sweating. The dose of the neutral camphorate is 8 to 12 grains, of the acid camphorate, 12 to 15 grains. Pyramidon Salicylate. This is a salt of pyramidon and sali- cylic acid. It is a white crystalline pow- der, soluble in 16 parts of water or 5 to 6 parts of alcohol. It is antipyretic, analgesic and antiseptic, and is recom- PROPRIETARY AND SYNTHETIC REMEDIES. 831 mended in rheumatic and gouty affec- tions, neuralgia, pleuritis, etc. The dose is 8 to 12 grains. Pyran. See Pyrenol. Pyrantin. (Phenosuccin.) This is a combination of phenacetin and succinic acid. It is in colorless needles, requiring 1400 parts of water for solution. The soluble form is a so- dium compound. Both forms are used as antipyretics in doses of 5 to 15 grains. Pyrenol. (Pyran.) (178) This is stated to be a chemical com- pound of salicylic acid, thymol and ben- zoic acid. It is a white, crystalline, slightly hygroscopic powder, having an aromatic odor and a sweetish taste. It is recommended as an antispasmodic in asthma, bronchitis and pertussis, an analgesic in rheumatism, neuralgia, sciatica, etc., and an expectorant in pneumonia. The dose is 8 to 15 grains three times a day. Pyridine. This is a liquid derived from coal tar oil and possessing strong basic prop- erties. It is contained in tobacco smoke. It is a colorless liquid when pure and fresh, soluble in water, alcohol, oils, etc., and of a very disagreeable, suffo- cating odor, and has therefore been used for denaturing alcohol. It is used by inhalation in asthma, 20 to 60 drops being allowed to evaporate from a saucer near the patient. Pyridine Tannate. This is prepared by pouring a solu- tion of pyridine into a solution of tan- nin in excess. The product is' a powder which is decomposed on exposure to light. It is used as a uric acid solvent and an intestinal astringent. Pyrodin. This is the same as Hydracetin, which see. Pyrodol. This is the formula as given by the manufacturers : Echinacea angusti folia oz. 2 x /& Creosotin (a distillation of wood tar) m. 50 Sodium pyro-phenolsul- phonate dr. 2 Arbor vita dr. 10 Phytolacca decandra oz. y 2 Potassium glyco muriate oz. 5 Aromatics m. 20 Succus vitis vinifera, q. s oz. 20 It is recommended for catarrh. Pyroferrine. (117) .This is stated to contain in each fluid- dram 2Y2 grains of iron pyrophosphate, 1/100 grain of strychnine, and 5 grains of diluted phosphoric acid. It also con- tains 12% of alcohol. Pyrofistine. This is stated to contain silica, mag- nesia, iron carbonate, gaultheria, pepper- mint, mixed with an antiseptic oil to form a paste. Pyroglycerin. This is a synonym for nitroglycerin. Pyrogallol-Bismuth. See Helcosol. Pyrosal. (Aceto-Salicylate of Anti- pyrin.) This is in white powder or colorless crystals, and almost insoluble in water. It is stated to contain 50% of antipyrin, 36% of salicylic acid, and 14% of acetic acid and is decomposed into these con- stituents in the intestines. The dose is 5 to 15 grains three times a day. Pyrozone. (121) This is a solution of hydrogen per- oxid. It is made of two strengths, 3% aqueous solution, and 25% ethereal solutions. Quartonol Tablets. (178) These are stated to contain 2*4 grains of each, calcium and sodium glycero- phosphates, l /2 grain of quinine glycero- phosphate and 1/100 grain strychnine glycerophosphate. 832 THE STANDARD FORMULARY Quesneville's Cream of Bismuth. According to Hager this is a mixture of bismuth subnitrate. Quickine. Carbolic acid part i Mercuric chlorid part 1/50 Alcohol and water parts 1000 -Ph. Ztg. Quina-Laroche. This is described by the makers as a "complete extract of yellow, red and gray cinchona, prepared in the form of a vinous elixir." Quinalgen. (Analgen — Benzalgen.) This is a derivative of chinoline, and occurs as a white, tasteless, odorless, crystalline powder, insoluble in water, sparingly solubl-e in cold alcohol, but readily soluble in hot alcohol. It is used against malarial fevers as a sub- stitute for quinine, also as an antineu- ralgic and analgesic for sciatica, mi- graine, rheumatism, etc., in doses of 5 to 15 grains two or three times daily. Quinilid Tablets. (117) These are stated to consist of 2^2 grains each of acetanilid and quinine sulfate. Quinaphthol. (Chinaphthol— Quinine Betanaphthol-Sulf onate. ) This is a compound of quinine and naphthol. It is a yellow crystalline, bitter powder, insoluble in cold water, slightly soluble in hot water and in alco- hol. It is used as an intestinal anti- septic and antipyretic in doses of 8 to 15 grains. Quincoca. (138) This is stated to be a combination of quinine, coca leaves, gentian, wild cherry, orange peel and aromatics ex- hausted with port wine. Quinic Acid. This is an acid naturally present in cinchona bark. It is in white crystals, soluble in water and alcohol and of an acid taste. It is used in uric-acid diath- esis, generally in the form of salts such as lithium quinate (urosin), piperazine quinate (sidonal), urotropin quinate (chinotropin), urea quinate (urol), etc. Quinidine. This is one of the alkaloids of cinchona. It is in colorless, lustrous prisms soluble in 20 parts of alcohol, almost insoluble in water. It is almost tasteless and hence is preferred instead of quinine, especially for children. It is used as an antiperiodic and antipyretic in doses of 3 to 30 grains, suspended in syrup. Quinine Formate. This is used in two forms, neutral and basic, the latter soluble in 5 parts of cold water. It is recommended for hypodermic use. Quinine Hydrochlorsulfate. This is produced by dissolving to- gether, in molecular proportions, qui- nine hydrochlorid and quinine bisul- fate, evaporating and crystallizing. It is in colorless crystals soluble in 1 part of water, and because of its ready solubility, is especially useful for hypodermic injection. Quinine Lygosinate. This is prepared by the reaction of quinine hydrochlorid with sodium lygos- inate. It is a fine, amorphous, yellow powder, of a bitter taste and a faintly aromatic odor. It is slightly soluble in water, soluble in 6 parts of alcohol, also soluble in oil and chloroform. It is decomposed by acids and alkalies. It contains about 71% of quinine. It is a non-toxic and non-irritant antiseptic, possessing very decided bactericidal de- odorizing and styptic properties. It may be employed as a dusting powder, in bandages, gauzes, suppositories, in the form of court plaster and in glycerin suspensions. Quinine Tonol. This is glycerophosphate of quinine. It is a white powder, sparingly soluble in water, more soluble in alcohol, and contains 68% of quinine. It is used PROPRIETARY AND SYNTHETIC REMEDIES. 833 chiefly in malaria associated with nerv- ous disturbances. The dose is 3 to 10 grains three times a day. Quinoline. (Chinoline.) This is a tertiary amine naturally present in coal tar. It is now prepared from aniline. It is a colorless liquid becoming yellow by age, and has a pecu- liar odor. It is miscible with alcohol and ether and is practically insoluble in water. It is used in water or alcohol as an antiseptic mouth or tooth wash, etc., and for preserving anatomical spec- imens. Quinoliv. This is described as a "tasteless, sol- uble powder of sulfate of quinine with olive oil." Quinopyrin. (Chinopyrin.) This is a combination of 3 parts of quinine hydrochlorid and 2 of antipyrin. It is a white powder, readily soluble in water, and is recommended for hypo- dermic use in malaria. Quinquinia. This is a similar preparation, ac- cording to a communication by Dr. Lee to the Phila. Med. and Surg. Re- porter years ago : Quinine alkaloid 15% Quinidine alkaloid 15% Cinchonidine alkaloid 15% Cinchonine alkaloid »-. 25% Chinoidine 30% Quionin. This is said to consist of 90% of "side bark" alkaloids and a small percentage of quinine. R. & H. Three Chlorides. See Henry's Three Chlorides. Rachitol. This is the suprarenal gland in tab- let form. Radal. This is said to be a prophylactic against gonorrhea consisting of a 20% solution of protargol. Radam's Microbe Killer. This is stated by the manufacturers to be composed of mire water charged with gases generated from the follow- ing ingredients : Flowers of sulfur. Nitrate of soda. Black oxide of manganese. Chlorate of potash. RadcliftVs Elixir. Aloes parts 23 Rhubarb parts 4 Cassia bark parts 2 Zedoary parts 2 Cochineal parts 2 Syrup of buckthorn ber- ries parts 60 Alcohol parts 150 Water parts 155 — Dorvault. Radium Fluid. This is said to be made by exposing normal salt solution to the emanations from a tube of radium bromid for 24 hours. The solution is impregnated with the properties of the radium, be- coming radioactive. Ransom's Hive Syrup and Tolu. This is stated to contain squills, 6%, senega root, 1%, tartar emetic, 1/10%, sugar, 63%, with a sufficient quantity of balsam of tolu and an aqueous solution of dracontium, lobelia and honey. Raymond's Disinfectant. According to the patent specifications, this is said to contain zinc acetate, boric acid, aluminum sulfate and acetate, so- dium hyposulfite, mercuric iodid, and acetic acid. Red Clover Compound. (Laxative Cordial.) (17) Each fluidram is stated to represent 15 grains of red clover, 8 grains of cas- cara sagrada, and 3 grains each of ber- beris aquifolium and iris versicolor. Regnault's Pate Pectorale. According to Hager, this is prepared from an infusion of 50 g. of pectoral species, 300 g. of gum arabic, 350 to 400 g. of sugar, and 3 g. of balsam of tolu. 834 THE STANDARD FORMULARY Regulin. (96) This is stated to be a mixture of agar-agar in a dry form with extract of cascara sagrada, representing 20% of an aqueous fluid extract of cascara sag- rada. It is in the form of odorless and tasteless brown scales which slowly ab- sorb water to form a jelly. It is rec- ommended for the treatment of habitual constipation in doses of a teaspoonful to a tablespoon ful once daily in stewed ap- ples, mashed potatoes, or similar food. Renaden. This is a trituration of an extract of pigs' kidneys, 1 part representing 2 parts of the fresh organ. It is used in uremia and nephritis in doses of 1 to 2 drams daily. It is also put up in 4-grain tab- lets. Renaglandin. This is described as a "concentrated solution of suprarenal gland." It is recommended as a hemostatic. Renastyptin. This is a solution of the hemostatic principle of the suprarenal bodies. Renatone. (211) Each dessertspoonft is stated to con- tain Hexa-cystine gr. 2 Lithium "benzo-citrate" gr. 1 Buchu gr. 4 Digitalis gr. l / 2 Triticum gr. 2 Potass, nitrate gr. 1 In an alkaline medium free from su- gar. It is also stated to contain 12% of alcohol. Renoform. This is a preparation of the suprare- nal capsule intended for use in coryza. Renol. This is described as a combination of pure "sodium lithiate." diuretin. dami- j ana. and digitalin, with alkalies and de- mulcents. Resaldol. This is a condensation product of saloform and re c orcin. It is a yellowish brown powder, odorless, of an astring- ent taste, and insoluble in water and dilute acids, soluble in alkalies. It is used as an intestinal antiseptic and as- tringent in doses of 5 to 15 grains 3 to 5 times daily. Resinol. s This is an ointment described as a "combination of the active principle of Juniperus oxycedrus, and a synthetical derivative of the coal tar series and bis- muth with lanolin and petrolatum." Resorbin. An ointment vehicle prepared by emul- sifying sweet almond oil and water with yellow wax, gelatin and soap. — Coblentz. Resorcinol. This is the_con-ect aooellation for re- sorcin. The name is also applied to a compound obtained by melting together iodoform and resorcin. It is a brownish powder of a slight iodin odor. It is used as an antiseptic application in pow- der form mixed with 1 to 4 parts of starch or in a 5 to 15% ointment. Respirazone. (194) This is stated to be composed of iodid and bromid of potassium, ipecac, lobelia, and motherwort. It is used for hay fever and asthma. Retinol. (Rosinol — Codal.) This is obtained by destructive dis- tillation of resin. It is an oily, viscid liquid of specific gravity 0.900. An internal and external antiseptic in ven- ereal and cutaneous affections ; also used as a solvent for phosphorus, salol, iodol, aristol, camphor, creosote, etc.. especially for remedies applied extern- ally for skin diseases. It is applied pure, or in ointment or liniment. Dose : 8 drops 4 to 6 times daily, in capsules. Rhei-Drastis. (198) This preparation is similar to "neu- tralizing cordial." Rheumacilate. This is stated to be chemically pure salicvlate of methvl. PROPRIETARY AND SYNTHETIC REMEDIES. 835 Rheumagon. (4) This is stated by the manufacturers to be composed of iodid and phosphate of sodium. Rheumatin. This is Saloquinine Salicylate, which see. The name is also applied to a preparation stated to contain in each fluidram 2 grains of sodium iodid and 26 grains of sodium phosphate. Rheum on. This is the name given to a paper bearing a layer of aromatic gums and balsams, and which is intended for the relief of rheumatic pains. The medi- cating ingredients consist of camphor, benzin (not benzoin), Mecca balsam, fir balsam and fluid extract of arnica. Rhinol. (138) This is stated to be a combination of aristol guaiacol, menthol, eucalyptol, and oil of saw palmetto, with a pure bland oil. Rhomnal. This is a nucleinic acid of French manufacture, obtained from the thymus gland of a calf. Rhomnoline is the cal- cium salt, and Rhomnogyre is the mer- cury salt of this acid. They are cred- ited with tonic and nervine properties. Ricin. This is described by the manufac- turers as a palatable castor oil. Ricinol Grape. (84) Each capsule is stated to contain 40 minims of pure castor oil. Ricord's Capsules of Copaiba and Tar. Hager gives this formula: Copaiba balsam g. 55 Magnesia, calcined g. 5 Pine tar : g. 5 Divide into 100 capsules. Ricqle's Alcool de Menthe. According to Hager this is a solution of 9 g. of oil of peppermint in 200 g. of alcohol. 53 Ripans Tabules. The formula is given as follows : "Soda" gr. 5 Rhubarb gr. 2 Aloes gr. J / 2 Ipecac gr. % "Nux" gr. % Peppermint <..gr. Y% Ringoline. This is stated to be a paste of equal parts of cod liver oil and glycerin with 3% of zinc oxid and Peru balsam. It is used for skin eruptions of infants, also as a vehicle for other substances such as tar, salicylic acid, etc. Robach's Bitters. According to Hager the principal in- gredients are gentian and angelica with smaller amounts of aromatic substances. It also contains traces of acetic ether, 36% of alcohol and 21% of sugar. Robbert's Camphor-Tar Ointment. The following is said to be the for- mula (N. I.) : Tar av.oz. 1 Camphor -. . . . .av.oz. 1 Lard av.oz. 8 Robin's Powder of Glycerophos- phates. Iron glycerophosphate g. 0.5 Calcium glycerophosphate g. 0.3 Magnesium glycerophosphate. g. 0.1 Ignatia g. 0.2 Egg albumin, dry g. 0.1 This is for one powder. — Bouch- ardat's Formulary. Robin's Pill Cascara Comp. These are stated to contain cascara, hyoscyamin, podophyllin, colocynth, with aromatics, q. s., to make i-grain pill. Pill Cascara Comp. strong is four times the strength of the preceding. Robinson's Elixir Paraldehyde. This is stated to contain 45 grains (10%) of paraldehyde to the fluidounce, dissolved in an aromatic menstruum. Robinson's Hypophosphites. Each fluidounce is stated to contain Sodium hypopliosphite gr. 2 Calcium hypoph'osphite gr. 1 ' j Iron hypopliosphite gr. 1 ' j 836 THE STANDARD FORMULARY Manganese hypophosphite gr. i z / 2 Quinine hypophosphite gr. $4 Strychnine hypophosphite gr. 1/16 Robinson's Phosphoric Elixir. Each fluidounce is stated to repre- sent Sodium phosphate gr. 12 Potassium phosphate gr. 4 Calcium phosphate gr. 4 Iron phosphate gr. 2 Free monohydrated phosphoric acid gr. 16 Roboline. (Roboline Cordial.) (167) Each wineglass ful or two tablespoon- fuls is stated to contain quinine, Y\ grain, strychnine, 1/400 grain, dilute phosphoric acid, 8 minims, extract of wild charry bark, extract of Oolong tea, 8 grains, combined with carminative aromatics. Roborat. This is an albuminoid dietetic made from grain. It is a fine white odorless and tasteless powder. It is said to con- tain a large amount of lecithin and gly- cerophosphoric acid. It is also said to be easily digested and absorbed even if given by enema. Roches' Embrocation. According to Mueller's analysis (in H.) this is composed of 5 g. of asafet- ida digested with 120 g. of olive oil for several hours, the oil is decanted and mixed with 4 g. of caraway and tur- pentine oils and a few drops of oil of bergamot. According to Hager's in- vestigations it is composed of about 50 g. of olive oil, 3 g. of oil of clove, 2 g. of oil of caraway, and 5 g. of tincture of opium. Rodagen. This is a preparation obtained from the milk of goats which have previously been deprived of their thyroid glands. The dried milk is triturated with 50% of milk sugar. The product occurs as a white, palatable powder. It is used in the treatment of exophthalmic goiter in doses of 5 to 10 g. daily. Roge's Purgative Powder. According to Dorvault, this is com- posed of 8 parts of calcined magnesia, 4 of magnesium carbonate, 26 of citric acid, 50 of sugar, and some oil of lemon. Ronozol Salts. These are compounds of mercury, po- tassium, sodium and zinc with diiodo- paraphenolsulfonic acid, which are rec- ommended as antiseptics. Roseter's Hair Regenerator. According to Hager, this is composed °f 345 g- of rose water, 50 g. of gly- cerin, 2 g. of lac sulfur and i l / 2 g. of lead acetate. According to Ch. and Dr. analysis it is composed of 44.8 grains of sulfur, 21.87 grains of lead acetate and 10 ounces of glycerin and water. Rotterine. Zinc chlorid gr. 45 Zinc sulphorcarbolate gr. 45 Salicylic acid. . ; gr. 6 Boric acid gr. 27 Citric acid gr. 1 Thymol gr. 1 Sodium chlorid gr. 2 l / 2 Distilled water fl.oz. 16 The tablets contain one-half the quan- tities of the solids mentioned above. This mixture was recommended by Dr. Rotter as an ideal antiseptic. Rubidium Bromid. This is in colorless crystals or white powder soluble in water. It is said not to cause gastric disturbance. It is used like potassium bromid in doses of 5 to 15 grains. Rubidium Iodid. This is colorless, cubical crystals of a bitter, saline taste and about as solu- ble in water as potassium iodid. It is used in place of the latter and is pre- ferred because it is said not to cause gastric disturbance. The dose is 5 to 10 grains. Rufus's Pills. These are the Pills of Aloes and Myrrh of the pharmacopeia. PROPRIETARY AND SYNTHETIC REMEDIES. 837 Russell Emulsion, The. This is stated to be a modified pan- creatic emulsion and to contain beef fat, and cocoanut, peanut, olive and clove oils. Sabalol. (138) This is described as a bland, oily base, which is a suitable vehicle for many medicaments. Sabalol Balsam. This is described as a "prepared com- bination of the active principles of the saw palmetto." Sabalol Spray. This is described as a combination of the active principles of saw pal- metto with eucalyptol, 2 x / 2 minims (5 drops), and menthol, 4 grains, to the ounce. Sabalol Tablets. This is described as a combination of the active principles of saw pal- metto with % grain of powdered cu- bebs and 1/200 grain of nitrate of san- guinaria to each tablet. Saccharin. (Anhydroorthosulfa- midobenzoic Acid — Benzoylsul- fonic Imide.) This is a white powder, about 300 times sweeter than sugar. It is only sparingly soluble in water, its solubility being increased by the alkali carbonates. The so-called "soluble saccharin" is a combination of saccharin and sodium bicarbonate. It is used as a sweetener when sugar is not admissible, as for diabetics. Sajodin. (Calcium Monoiodobehe- nate.) This is a colorless, odorless and taste- less powder, insoluble in water, alco- hol or ether, soluble in chloroform. On exposure to light it becomes yellow superficially without material decompo- sition. It contains 26% of iodin. It is used for the same purposes as other iodids. It is said to be free from un- pleasant and deleterious side effects. The dose is 15 to 45 grains daily. Sal Aperien's. (154) This is stated to be composed of so- dium sulfate, magnesium sulfate, potas- sium sulfate, sodium chlorid,-free sulfur and "iron crenate." Sal-Eliminant(Dusal.) This is given as the "drachm for- mula :" Lithium carbonate gr. 3 Sodium sulfate gr. 20 Sodium phosphate gr. 10 Sodium chlorid gr. 3 Potassium bicarbonate gr. 5 Sal-Ethyl. (Ethyl Salicylate.) (159) This is a colorless, transparent, vola- tile fluid, which is designed to take the place of methyl salicylate or oil of wintergreen. It is supplied in 5-minim globules. Sal-Codeia. (20) This is said to be 5-grain tablets con- taining 5 grains of salacetin and % gr. of codeine sulfate. Sal Hepatica. (29) This is described as a combination of salts similar to those contained in the bitter waters of Bohemia, fortified by the addition of lithium and sodium phosphates. Sal Lister. This is described as a soluble powder stated to contain carbolic and boric acids, boroglyceride, sozoiodol, hydras- tine (white alkaloid), sodium biborate (dehydrated crystals), with the cry- stalline principles of eucalyptus, win- tergreen, thyme and mint. Sal-Lithia Tablets. (154) These are stated to be composed of Ext. cascara sagrada gr. 2 Lithium salicylate gr. 2 Colchicine salicylate gr. 1/500 Pilocarpine salicylate gr. 1/200 Sal Physiologicum Poehli. See Poehl's Physiologic Salt. Sal Prunelle. This is in balls consisting of potas- sium nitrate with a small amount of the sulfate. 838 THE STANDARD FORMULARY Salacetol. (Salicylacetol.) This is in fine, shining bitter needles or scales, which are insoluble in cold water, sparingly soluble in cold alco- hol, but freely soluble in hot alcohol, in ether, chloroform and oils. It is an internal antiseptic in infec- tious diarrhea, gouty rheumatism, etc. Designed for same uses as salol. Dose: 30 to 45 grains in a fluidram of castor oil, preferably in the morning. Salactol. This is stated to be a preparation containing the sodium salts of salicylic and lactic acids. It is to be dissolved in 1% hydrogen peroxid and applied to the throat in diphtheria. Salalgin. (63) Each dessertspoonful is stated to con- tain Strontium salicylate gr. 6 Strontium lactate gr. 4 Strontium iodid gr. 1 Green tr. gelsemium m. 4* Wine of colchicum m. to Hydrastoids, q. s. Salamid. (131) This is described as an amidogen de- rivative of salicylic acid, and is said to be made by the action of ammonia upon natural oil of wintergreen. It is in white or pinkish white crystals, which are easily soluble in alcohol and ether but sparingly in water. Aqueous solu- tions are decomposed by alkalies. It is used in the same indications as the salicylates but the ammonia combination is said to prevent cardiac depression. Salaperient. (105) This is an effervescent salt, each heaping teaspoonful of 4 grains each of potassium and sodium sulfates and 16 grains of magnesium sulfate. Salenal. This is an ointment containing y$ of salene. It is used externally for rheumatism. Salene. This is a preparation which is a mix- ture of methylglycol and ethylglycol salicylates. It is used as a liniment or embrocation, mixed with equal parts of alcohol or castor oil. Salibromin. This is dibromsalicylic methyl ester. It is a white, tasteless powder of a faint odor, insoluble in water and in acids, but soluble in alkalies. It is used as an antipyretic and antirheumatic in doses of 8 grains 4 to 10 times daily. Saliciform. This is described as a pinkish-white, crystalline powder, used as an antirheu- matic, antipyretic and analgesic. Salicylamide. This is obtained by acting upon methyl salicylate with dry ammonia. It is in thin, colorless plates, soluble in alcohol, ether or chloroform, spar- ingly soluble in water. It is used as a substitute for salicylic acid in doses of 3 to 5 grains every 3 or 4 hours. Salicyibromanilid. Same as Antinervin, which see. Salicylos. (141) This is an effervescent granular pow- der, each dessertspoonful of which is stated to contain 10 grains each of strontium and ammonium salicylates with an excess of a non-irritating alka- line salt. Salifebrin. This is said to be a mixture of ace- tanilid and salicylic acid. Saliformin. (Form in or Urotropin Salicylate.) (130) This is the salicylate of hexamethyl- enamine. It is prepared by dissolving equal weights of hexamethylnamine and salicylic acid in water and evaporat- ing the solution to dryness at a tem- perature below 6o° C. It is a white, crystalline powder, having an acidulous and disagreeable taste, readily soluble in water or alcohol. It is decomposed by basic substances (soluble hydroxids, carbonates, etc.) and by strong acids. It is incompatible with salts of iron and other metals which form insoluble com- pounds with salicylates. PROPRIETARY AND SYNTHETIC REMEDIES. 839 It is recommended as a genitourinary antiseptic and uric acid solvent in cases of cystitis, lithiasis and bacterial affec- tions . of the urinary tract in doses of 5 to 30 grains. Saligenin. (Ortho-oxybenzylic or Sa- licylous Alcohol.) This is in colorless scales, soluble in alcohol, ether or hot water. It is used in the treatment of rheumatism, malaria, etc. Dose : 8 to 15 grains every 2 or 3 hours. Saliodin. (Densten.) The formula for this preparation is given in this wise. Each 20 grs. con- tains approximately : Salicylic acid (aceto-salicyl- ate) gr. 15 Iodin (iodate) equivalent to iodide potass gr. 15 Acetic acid (acetate), equiv. to acetate potass gr. 5 Aconite, equiv. to* Tr. Aconite R drops 4 Bryonia, equiv. to Tr. Bryonia drops 4 Colchicum, equiv. to Vin. Colchicum Root drops 15 Capsicum, equiv. to Tr. Capsicum drops 2 Oil gaultheria m 3 Salipyrine. (Antipyrine Salicylate — Salazolon.) This is a combination of salicylic acid and antipyrine. It is in the form of a white, crystalline powder "or as tubular crystals, odorless, soluble in 200 parts of cold water and 40 parts of boiling water, readily soluble in alcohol. It is incompatible with acids, alkalies and tannins. It possesses the properties of both antipyrin and salicylic acids. It is recommended for sciatica, rheumatism, influenza, pleurisy, etc., in doses of 5 to 30 grains about 3 times daily. Salit. This is said to consist chiefly of the salicylic ester of borneol. It is an oily liquid, nearly odorless, insoluble in water, slightly soluble in glycerin, read- ily soluble in alcohol, ether or oils. It is incompatible with alkalies. It is used externally by inunction in a mix- ture with equal parts of olive oil for gout, rheumatism, neuralgia, pleurisy, etc. It is said to be absorbed by the skin and be decomposed by the body, salicylic acid being liberated in the tis- sues. Salitannol. This is a condensation product of sali- cylic and gallic acids. It is a white amorphous powder, insoluble in water, ether or chloroform, sparingly soluble in alcohol, but is easily dissolved by caustic alkalies. It combines the prop- erties of salicylic and tannic acids and is used for wounds and in intestinal catarrh in doses of 15 grains 3 times a day. Salithymol. (Thymol Salicylate.) This is a white, crystalline powder of sweetish taste, soluble in alcohol and ether, slightly soluble in water. It is used as an internal antiseptic in the- same doses as salol. Salitonia. (Saline Tonic.) (163) This is stated to be a composite salt composed of chlorids, bromids, and car- bonates of lithia, potassium, strontium, sodium, etc. It is put up in powder and tablet forms. Salocoll. (Phenocoll Salicylate.) This is prepared by neutralizing hot aqueous solution of salicylic acid with phenocoll. It is in fine, white crystal- line needles, of a sweetish taste, solu- ble in 200 parts of cold water, readily soluble in hot water. It combines the properties of phenocoll and salicylic acid and is useu for rheumatism, gout, chorea, influenza, etc., in doses of 15 to 30 grains. Salocreol. This is the salicylic ester of creosote. It is a brown, oily liquid, almost odor- less, insoluble in water readily soluble in alcohol, ether, chloroform and oils. It is used externally for facial erysip- elas, acute and chronic inflammation of the lymph glands and chronic arthritis. 840 THE STANDARD FORMULARY Salol. (Phenyl Salicylate.) This is a white, crystalline, odorless powder, almost insoluble in water, sol- uble in 10 parts of alcohol, and readily soluble in ether, chloroform, and fluid and volatile oils. When taken, it passes unabsorbed through the stomach into the intestinal tract, where the alkaline fluids decom- pose it into its constituent parts, sali- cylic and carbolic acids. It is, there- fore, a valuable intestinal antiseptic in diarrhea, typhoid fever, etc. It is also useful as a coating for pills which are intended to act only on the intestines. The dose is 15 to 30 grains as an antirheumatic ; for other purposes, the dose is 5 to 15 grains. Salomon's Balm of Gilead. This is an aphrodisiac remedy for- merly patented in England. Hager gives the following as the formula : Cardamon g. 30 Cassia bark g. 30 Mecca balsam g. 3 Tincture of cantharides g. 1.5 Sugar g. 250 Alcohol g. 350 Water g. 150 Salophen. (Acetylpharamidophenol Salicylate.) It is in small, white, crystalline leaf- lets or powder, odorless and tasteless and containing 51% of salicylic acid. It is almost insoluble in cold water, more soluble in warm water, but freely soluble in watery solutions of the alka- lies and in alcohol, ether and benzene. It is incompatible with alkalies which decompose it. The actions of salophene resemble those of phenol. It is not changed in the stomach but is decom- . posed in the intestines into salicylic acid and acetylparamidophenol which latter, unlike phenol, is not toxic. It acts as an antirheumatic, antipyretic, antiseptic and analgesic, and has been recommended for rheumatism, gout, neuralgia, typhoid fever, and as an in- testinal antiseptic, in diarrhea and dysentery. The dose is 5 to 15 grains 3 or 4 times daily. Saloquinine. (Quinine Salicylic Ether — Salicyl quinine. ) This is a white crystalline powder, perfectly tasteless and odorless, insol- uble in water, soluble in acidulated water and moderately soluble in alco- hol or ether. It is incompatible with acids. It is a tasteless substitute for quinine and salicylic acid. It contains 73% of quinine. The dose is 8 to 30 grains. Saloquinine Salicylate. It is prepared by adding salicylic acid to a hot alcoholic solution of saloqui- nine. It is a white, tasteless powder, sparingly soluble in water, soluble in chloroform and hot alcohol. It is in- compatible with alkaline liquids. It is recommended for acute rheumatism, neuralgia, and gonorrheae inflammations in doses of 15 grains. Salosantal. This is a composition in which salol and sandalwood oil are the ingredients. Salubrin. This is put up as a Swedish specialty which is stated to contain 22% ethyl acetate (acetic ether), 48% of ethyl al- cohol, and .03% of ethyl aldehyde. The Pharmaca Composita (Swedish) gives the following formula: Acetic acid parts 2 Acetic ether parts 23 Alcohol parts 50 Water parts 23 Acetic acid of the Swed. Pharm. con- tains 25% of absolute acetic acid. Salumin. (Aluminum Salicylate.) This is a white powder, insoluble in water. It is used as an external anti- septic in nasal and pharyngeal catarrh, ozena, etc. It is used as a dusting powder, either pure or diluted. Salvitae. This is the composition as given on the label: Magnes. sulph. Sod. sulfate. Sodium forma-benzoate. PROPRIETARY AND SYNTHETIC REMEDIES. 841 Sodium, lithium and strontium lacto- citrate. Caffeine. Quinine. Lacto-phosphate of sodium and cal- cium. Sodium and potassium bicarbonates with citric and tartaric acids. Sanatogen. This is a combination of casein, 95%, and sodium glycerophosphate, 5%. It is a fine white powder soluble in water. It is recommended as" a food in weaknesses of the digestive function, and as a nerve nutrient in neurasthenia, marasmus, etc. Sancodol. (160) This is described as an emulsion of oils of santol, abies balsamea, and copaiba. Sandal-Etto. Each fluidounce is stated to contain Saw palmetto gr. 6o Coca leaves gr. 20 Kola nut gr. 20 Damiana gr. 20 Nux vomica gr. 5 Sandalwood gr. 5 Potassium iodid gr. 4 Ammonium chlorid gr. 4 Aromatics, q. s. Sanford's Extract of Jamaica Ginger. This is stated to contain selected gin- ger, choice aromatics, and genuine French brandy. Sangostol. This is a solution said to contain iodin in combination with both calcium and iron. It is used in rachitic and scrofulous diseases. Sangrenal Preparations. (121) These are prepared from the fresh suprarenal glands of sheep. There arc three forms, the powder, lozenges, and tablets. Sanguestine. (117) This is described as the pure crystal- lized hemostatic and blood-pressure rais- ing principle of the suprarenal gland. Sanguestine Chlorid Solution. This is a 1:1000 solution of sangues- tine chlorid in normal saline liquid. Sanguinal. This is stated to contain 40% of the natural salts of blood, 10% of oxy- hemoglobin, and 44% of peptonized blood almumin. It is marketed only in the form of pills. Sanguinol. (148) This is stated to be liquid petrolatum with nitrate of sanguinarine and anti- septics. It is used for spraying the nose and throat. It is said to be made after the formula of the Brooklyn Throat Hospital. This name is also applied in Europe to a preparation made from the blood of young calves. It is a dark red, fine powder, soluble in water. Sanitaris Metral Disks. (136) These are stated to be made with a vehicle of borated glyco-gelatin, each disk containing ichthyol, 5 grains, anti- pyrin, 1 grain, zinc sulfate, T /\ grain, zinc chlorid, Yz grain, creosote, l /% grain, benzoic acid, 2 grains, fluid hydrastis, Y\ grain, extract of henbane, Y\ grain, menthol, 1/10 grain, and boroglyceride. Sanitas. According to the specifications of a U. S. patent, issued in 1883, it is made by the passage of oxygen through tur- pentine or other hydrocarbon containing a terpene or cymene. It is used to make a disinfecting oil, soap, insecticide, sheep dip, salve, etc. Sanmetto. This is said to be a blending of true and saw palmetto in a pleasant, aro- matic vehicle. San-Methyl. (84) This is stated to be a 10-minim cap- sule containing methylene blue, salol, santal, cubeb, copaiba and matico. Sanoform. (Methyl Ether of Diio- dosalicylic Acid.) A white, odorless, tasteless, perma- nent powder containing 63% of iodin. 842 THE STANDARD FORMULARY It is soluble in alcohol, ether or petro- leum. It is a drying antiseptic like iodo- form. On contact with the moist sur- faces of tissues it is said to slowly liberate iodin and salicylic acids. Sanolin-Bahr. This is stated to be a solution of sali- cylic acid, glycerin and oil of orris in alcohol. It is used for perspiring feet. — Ph. Ztg. Sanose. This is a dietetic preparation stated to contain 80% of casein and 20% of albumose. It is a white, odorless and tasteless powder which forms an emul- sion-like mixture when stirred with water. It is recommended as a useful food in wasting diseases such as tubercu- losis, cancer, diabetes, etc. Sanosin. This was heralded abroad as a new remedy for tuberculosis. It was de- scribed as being a mixture of sulfur, charcoal, powdered eucalyptus leaves, and oil of eucalyptus. It was used by igniting it and inhaling the fumes. Santal-Grape. (84) This is described as a 5-minim cap- sule containing East India oil of santal. Santal-Midy. These are 5-minim spherical capsules containing pure oil of sandalwood. Santal Ostind. These are described as 5 min. santal pearls. Santalets. (182a) These are described as globular gela- tin pearls, each containing 5 minims of pure santal oil. Santaloids. (187) These are described as capsoids each containing 5 minims of East India san- dalwood oil. Santaloids Comp. contain 1 minim each of East India sandalwood oil and oil of copaiba, and 3 minims of Haarlem oil. Santalol Formaldehyde. This is a patented product of the action of formaldehyde on oil of santal in the presence of inorganic acids. It is a thickish, yellowish liquid which breaks up in the presence of water into its components. It is employed in inflam- matory conditions of the kidneys and bladder. Santheose. This is the name given to a theo- bromine of French manufacture. Santolin Capsules. Each 10-minim capsule is stated to contain oleoresins of cubebs, copaiba and matico, English oil of santal, salol, and diastase. Santyl. (109) This is the salicylic ester of santalol, containing 60% of the latter. According to the German patent, the neutral esters of sandalwood oil are produced by heat- ing the oil with the respective anhy- drides and subsequent purification of the product. This is a yellowish oil with a faintly balsamic odor and taste. It is insoluble in water but soluble in about 10 parts of alcohol and in ether. It is said that to pass the stomach unchanged but is slowly split up in the intestines into santalol and salicylic acid. It is given for the same purposes of oil of santal. It is put up for the market in half-ounce vials and 7-drop capsules. San-Urina Cordial. (136) This is stated to be composed of saw palmetto berries, damiana leaves, buchu leaves, uva ursi. juniper, sandal, eucalyp- tus and claret wine. Saparaform. This is a paraform-soap solution ob- tained by dissolving paraform to the extent of 3 to 5% in liquid potassa soap. Sapocarbol. This is a solution of cresols and po- tassium soap. Tt is used as an anti- septic. PROPRIETARY AND SYNTHETIC REMEDIES. 843 Sapodermin. This is a superfatted soap containing mercury. It is put up in two strengths, viz., i% and 1/5% respectively of mer- cury albuminate. Sapolan. This is a preparation said to contain 5 parts of crude naphtha obtained by distillation, 3 parts of lanolin and 3 or 4% of anhydrous soap. It is a brown- ish-black ointment which resembles tar preparations in its effects. Sapophthalum. This is the name given to a neutral cocoanut oil-potassa soap containing added glycerin. Sapozol. This is described as liquor cresoli saponatus. Saprol. This is a dark brown, oily substance, prepared by mixing crude cresols with hydrocarbons from petroleum containing about 40% of the former. It is insolu- ble in water, and is inflammable. It is used as a disinfectant and deodorant of stools. Saratoga Ointment. (94) This is stated to be made from bor- acic acid, zinc oxid, eucalyptol and pe- troleum. Satyria. This is stated to contain saw pal- metto, false bittersweet, couch grass, "moyra pauma," phosphorus, syrup, and aromatics. Savonal. This is a liquid soap made by saponi- fying olive oil with potassium hydroxid, precipitating the fatty acids with hydro- chloric acid, dissolving the precipitate in alkalies to complete neutrality and adding glycerin and water. Savaresse's Capsules. These are capsules made of mem- brane, each one containing 10 drops of sandalwood oil. Saxin. (32) This is a sweeting agent said to be 600 times sweeter than sugar. Scabiol. This is a compound of storax (20%) alcohol and water, and is a brownish- red, odorless liquid. It is used chiefly for scabies. It is said not to soil the clothing nor to irritate the skin. Scammonin. (Convolvulin.) This is derived from scammony resin. It is a whitish powder soluble in alco- hol, ether or solution of potassium hy- drate. It is a hydragogue cathartic in doses of 3 to 8 grains. Schistiol. .JChis is a substance derived from some bituminous rocks found in France. It is in masses of a dark brown color and a bituminous odor. It is applied extern- ally for skin diseases. Schlotterbeck's Compound Mixture of Glyconin. See Mixture Glyconin Comp. Schlotterbeck's Compound Mixture of Hydrastis. This is stated to contain hydrastis, syrup rhubarb and potassium, "sol. pep- sin," and a pancreatic solution (prepared from the fresh stomach and pancreas of the pig.) Schlotterbeck's Syrup Mangan Comp. See Syrup Mangan Comp. Schlotterbeck's Syrup Phospho- Chloride Iron. See Syrup Phospho-Chloride Iron. Schreyer's Toothache Pellets. Oil of clove gr. 15 Oil of cassia gr. 15 Black pepper gr. 60 Sodium chlorid gr. 60 Acacia gr. 60 Make into pellets weighing 8 grains each. — Wittstein. Schroer's Hair Dye. According to Fischer's analysis, this is a solution of 1 part of silver nitrate in 10 parts of water and 1 part of strong ammonia, colored with copper sulfate. 844 THE STANDARD FORMULARY Schultze's Blood-Purifying Powder. Sodium sulfate, dried parts 2 Magnesium sulfate, dried. . .parts 14 Sodium chlorid parts 3 Tartaric acid parts 3 Sodium bicarbonate parts 4' — Hager. Scopolamine Hydrobromid. This is identical with hyoscine hydro- bromid but is much lower in price. Scott's Emulsion. This is stated by the manufacturers to contain 45% of cod liver oil, 14% of glycerin, 6 grains of calcium hypo- phosphite and 3 grains of sodium hypo- phosphite to the fluidounce. Scopomorphine. See Euscopol. Sedative Compound Tablets. Each tablet is stated to contain Dried sulfate of iron gr. 1 Extract of valerian gr. 1 Extract of musk root gr. 1 Asaf etida gr. 1 Arsenous acid gr. 1/60 Sedative Granules. Each granule is stated to contain Aconitia gr. 1/200 Digitalin gr. 1/200 Gelsemin , gr. 1/120 Veratrine sulfate gr. 1/100 Extract of henbane gr. 1/16 Secacornin. (98) This is a standardized sterile liquid preparation of ergot, 1 cc. being equal to 4 g. of drug. This was formerly known as ergotin. — Keller. Sedalole Syrup. (182a) This is stated to represent tolu, blood- root, squill, wild cherry, balm of gilead buds, and heroin (1/24 grain to the fluidram). Seigel's (Mother) Curative Syrup. See Shaker Extract of Roots. Seller's Tablets. As put up by manufacturers, these tablets generally are composed of about the following : Sodium bicarbonate gr. 5 Sodium biborate gr. 5 Sodium chlorid gr. 5 Sodium salicylate gr. 7/24 Sodium benzoate gr. 7/24 Thymol gr. 7/48 Eucalyptol , gr. 7/48 Menthol gr. 7/96 Oil of wintergreen gr. 7/96 Senckenberg's Migraine Pastilles. Each contains Antipyrin gr. 4^ Acetanilid gr. 7^ Rhubarb gr. 24 Cinchona gr- V2 —Ph. Centralh. Senecin and Viburnin Tablets. (160) Each tablet is stated to contain Extract of senecio gr. \ x /i Extract of virburnum gr. 1 Extract of caulophyllum. . . .gr. l / 2 Extract of belladonna gr. 1/20 Reduced iron gr. 1 White alkaloid of hydrastis. .gr. 1/30 Aromatics and carminatives. Sennine. This is sold in a 2-ounce box with an inner sprinkle-top cover, and is stated to be a combination of boric acid and phenol (carbolic acid). Sepdelin. This is a syrupy liquid of pleasant taste containing ]/>% of iron iodid. It is a German specialty. Serosine. A white powder, which is a mixture of acetanilid and sodium bromid. — Notes on New Remedies. Serum Paste. This is a mixture of fresh serum from ox-blood mixed with 25% of zinc oxid and sterilized at 70 C. It is used as a covering for diseased surfaces. Seven Barks. (Vinegar of Seven Barks — Acetum Hydrangeae.) The label states that the bottle con- tains 3 ounces of vinegar of seven barks concentrated to 1 ounce ; farther on it is stated that it is made according to this formula : Extract of hydrangea lb. 1 Extract of poke lb. 12 Extract of culver lb. 12 Extract of dandelion lb. 12 Extract of ladies' slipper lb. 12 Extract of colocvnth lb. 12 Extract of blood root lb. 6 PROPRIETARY AND SYNTHETIC REMEDIES. 845 Extract of blue flag lb. 6 Extract of stone root lb. 6^4 Extract of golden seal lb. 7^> Extract of mandrake lb. 24 Extract of black cohosh lb. 24 Extract of butternut lb. 48 Spirit of sea salt lb. 14^ Aloes lb. 10 Borate of soda _ lb. 15 Infusion of 4^2 lbs. capsicum. Sassafras, powder lb. 11 Ginger lb. 6 Sugar-house syrup gal. 40 Water, to make gal. 98 Sevetol. (Emul. Sevi Comp.) (221) This is described as a natural emul- sion of mixed fats and oils containing mixed fats and oils, 30%, proteids, 3A%, carbohydrates, 3 X A%, alcohol, 5 3 A%- The proteids and carbohydrates are said to be in an assimilable form. Sextonol Tablets. (178) These are 5-grain tablets, each con- taining 2 grains each of calcium and so- dium glycerophosphates, T / 2 grain of iron glycerophosphate, Y\ grain of man- ganese glycerophosphate, and 1/200 grain of strychnine glycerophosphate. Shaker Digestive Cordial. The following is the formula given by the manufacturer : Extract of blue flag... lb. 1, oz. 2^4 Ext. of culver's root., .lb. 1, oz. 2^4 Extract of stillingia. . .lb. 1, oz. 2^4 Extract of poke root. .lb. 1, oz. 2^4 Extract of butternut/, .lb. 1, oz. 2^4 Extract of dandelion, .lb. I, oz. 2^/4 Extract of prince's pine oz. 15 Extract of mandrake oz. 12 Extract of gentian oz. 6 Extract of colocynth oz. 6 Extract of cohosh lb. 1, oz. 14 Dextrose lb. 520 Boric acid lb. 17 Dextrin lb. 442 Scale pepsin lb. S l A Maltose : lb. 182 Hydrochloric acid C. P. .. .sufficient Sodium chlorid lb. 9 California sherry wine gal 90 Water, to make gal. 215 The extracts are stated to be made by the special process peculiar to the Shakers of Mount Lebanon, N. Y. ; the pepsin is made according to Russell's patented process; the hydrochloric acid is added in sufficient quantity so that the mixture contains %%. Shaker Extract of Roots. (The Siegel Curative Syrup.) The following is the formula given by the manufacturer : Extract of blue flag lb. 6y± Extract of culver lb. 6^4 Extract of stillingia lb. 6]4 Extract of poke lb. 6 I /i Extract of butternut lb. 6j4 Extract of dandelion lb. 6*4 Extract of prince's pine lb. 5 Extract of mandrake lb. 4 Extract of gentian lb. 2 Extract of colocynth lb. 2 Extract of black cohosh lb. 10 Aloes lb. 9 Powdered capsicum lb. 1 Powdered sassafras bark lb. 10 Borate of soda lb. 10 Spirit of sea salt lb. 12 Sugar-house syrup .gal. 30 Water, to make gal. 90 Shiloh's Consumption Cure. This is stated to contain glycerin, oil of tar, peppermint, extract of lobelia, ex- tract of licorice, terpin hydrate, syrup, / and % grain of heroin and 2 l / 2 minims of chloroform (in the form of chloro- form water) to the fluidounce. Sic. This is a serum obtained from the substance and the cortex of the suprare- nal gland of the ox. It is a light yellow liquid which is said to be especially use- ful in whooping cough. Sicco. This is a reddish-brown crystalline powder, soluble in water, made from hematogen. It is used mainly for ane- mia in doses of 15 to 30 grains. Siccols. These are dry mixtures of various oils or oleoresins, such as castor or san- tal oils or oleoresin of male fern, with magnesium carbonate and glycerin. Sidonal. (Piperazine Quinate.) This is the normal salt of piperazine and quinic acid. It is a white crystal- line powder, of a faint acid taste, and is very soluble in water. Its incompatibili- ties are those of the alkaloidal salts 84fi THE STANDARD FORMULARY generally. It is recommended as a uric acid solvent in gout, neurasthenia, etc., in doses of 15 to 20 grains 5 to 6 times daily, well diluted with water. Sidonal New. This is the anhydride of quinic acid. It is used the same as sidonal. It is a white, odorless powder, very soluble in hot or cold water or in alcohol. Silberol. This is chemically silver sulfocarbo- late. It is recommended for use as in- jection in gonorrhea, for some eye dis- eases, etc. Silver Casein. See Argonin. Silver Citrate. See Itrol. Silver Fluorid See Tachiol. Silver Iodid. This is a voluminous yellow powder, which is used internally for syphilis in doses of 1/12 grain and as an injection for urethritis in 5 to 10% solutions. Silver Lactate. See Actol. Silver Nucleide. See Xargol. Silver Picrate. See Picratol. Silver Protalbin. See Largin. Silver Proteinate. See Novargan. Silver- Vitellin. See Argyrol. Singleton's Eye Ointment. This has apparently the same compo- sition as ointment of nitrate of mercury. — Cooley. Singleton's Ointment. According to Hager, this is a mixture of 1 part of arsenic sulfid and 24 parts of hog's lard. Sirolin (Sirsol.) (98) This is a syrupy solution of thiocol, containing 6 grains of thiocol to the fluidounce. Snyder's All-Food Emulsion. This is stated to be made from cod liver oil, Iceland moss and fruited barley malt whisky. Sodium Betanaphtholate. See Microcidin. Sodium Borosalicylate. This is said to be prepared by heating together 5 parts of boric acid, 13 parts of sodium salicylate and 28 parts of water. The syrupy liquid is then evapo- rated upon a sand bath until it forms a white mass. It is stated to be an active antiseptic. Sodium Cacodylate. (Sodium Di- methylarsenate.) This is a white powder, very soluble in water. Its action is very similar to that of other arsenic compounds, but is much less toxic because the arsenous acid is liberated slowly in the body. The dose is y 2 to 2 grains. Sodium Cinnamate. See Hetol. Sodium Diiodosalicylate. This is in colorless leaflets or needles which are soluble in 50 parts of water. It is used as an analgesic in doses of 3 to 10 grains several times daily, and is used externally as an antiseptic. Sodium Fluorid. See Fluorol. Sodium Glycerophosphate. Owing to its extreme deliquescence, this is marketed as a moist, colorless mass containing 75% of the salt. It is used in the form of solutions and syrups, also hypodermically. For hypodermic use it should be dissolved in boiled, dis- tilled water. The dose is 3 to 10 grains. Sodium Ichthyol. See Ichthyol- Sodium. Sodium Lygosinate. See Lygosine. Sodium Perborate. See Perborate of Sodium. Sodio-Phos. Comp. (Liquid Sodium Phosphate Comp.) (182a) Each fluidounce is stated to contain 1 ounce of C. P. sodium phosphate. PROPRIETARY AND SYNTHETIC REMEDIES. 847 Sohn's Wine Hypophosphites Comp. See Elixir Vigorans. Solurol. (Thyminic Acid.) This is a yellowish brown, almost tasteless powder, soluble in water. It has the property of dissolving its own weight of uric acid at a temperature of 20° C. and more is dissolved at higher temperatures. The dose is 4' to 8 grains 3 times a day. Sol. Anti-Phthisis. (118) Each fluidounce is stated by the manu- facturers to contain Terebene m. 5 Acetylphenylhydrazin gr. 1 Guaiacolyalerianacetate gr. 20 Caffeine citrated gr. 30 Nitric acid gr. % Chromic acid gr. iji It is also stated to contain 20% of al- cohol. Solution Bismuth and Hydrastia. See Blenol. Solution of Bromide of Strontium. (Paraf-Javal.) Each tablespoonful is stated to con- tain 30 grains of strontium bromid. Solution of Burdock, Compound. ». See Liquor Lappae Comp. Solution of Chloro-Phosphide of Ar- senic. Arsenous oxid gr. 15 Diluted hydrochloric acid...fl.oz. i l / 2 Distilled water sufficient Phosphoric acid a few drops Dissolve the arsenous acid in the hy- drochloric acid and 3^ fluidounces of water by the aid of a gentle heat, add water to make 1 pint, and then the phos- phoric acid. — Fr. Sieker. Solution of Ferrous Malate. (6) Each fluidram is stated to contain 4 grains of iron malate. Solution of Hypophosphites. (180) This preparation is described as an aqueous solution of the hypophosphites of lime and soda, each fluidounce con- taining 40 grains of the combined salts. Solution of Hypophosphites Comp. (221) Each fluidounce is stated to contain 4 grains each of calcium and potassium hypophosphites, 2 grains of iron hypo- phosphite, 1 grain of sodium, manganese and quinine hypophosphites, and 1/32 grain of strychnine hypophosphite. Solution Iodo Bromide of Calcium Compound. (194) The component parts are stated to be bromin, iodin, chlorin, calcium, magne- sium, iron, sodium and potassium. Solution of Lactate of Strontium. (Paraf-Javal.) Each tablespoonful of this solution contains 30 grains of lactate of stron- tium. Solution of Lecithin. (70) Each fluidram is stated to contain 1 grain of lecithin. See also Lecithin Solution and Leci- thine Clin. Solutol and Solved. These are mixtures of crude cresol and solution of soda containing 25 to 50% of cresol. Solvosal. (Solvosal-Lithium.) This is soluble in water and is used as a diuretic and antiarthritic, mainly in gouty conditions. Owing to its mild ac- tion, it is claimed to be superior to the ordinary salicylic combinations. The dose is 4 to 8 grains 3 or 4 times a day. Solykrin Pills. These are stated to be composed of 15 parts of solved, 5 of lysol, and 2 of cre- olin. They have been recommended for puerperal fever. Somatose. This is a preparation in which the al- buminous, nutritive portions of flesh have been converted into soluble albu- moses. It is a pale-yellowish powder, readily soluble in water, forming an al- most odorless, tasteless solution. It is employed as a food for persons suffering from weak digestion, or for invalids and convalescents, /i to 1 av. ource being given at a time, in milk, cocoa or soup. 848 THE STANDARD FORMULARY There is also Somatose-Cocoa, Soma- tose-Chocolate, and Somatose Biscuit. See also Lacto-Somatose and Ferro- Somatose. Sommerbrodt's Creosote Capsules. See Creosote Capsules. Somnal. This is said by the Ph. Rundsch. to be an alcoholic solution of chloral hydrate and urethan. Somnin. This is described as a compound of boric acid and phenols and is used as an antiseptic. Somnoform. This is the name given to an anes- thetic mixture composed of Ethyl chlorid parts 12 Methyl chlorid parts 7 Ethyl bromid part 1 Somnone. (188) Each fluidram is stated to represent 30 grains of poppy (denarcotized), 20 grains of lupulin, and 10 grains of lactu- carium. Somnos. (141) This is also called elixir trichlorethi- dene propenyl ether. It is stated to con- tain 25 grains of chloral glycerolate per fluidounce, and also contains 2% of alco- hol. The chloral glycerolate is stated to be a definite substance obtained by the chemical reaction of glycerin upon chlo- ral, containing no uncombined chloral. It is used as a hypnotic and cerebral sedative in doses of 2 to 4 fluidrams. Somnus Sedatus. (135) Each fluidounce is stated to represent Chloral hydrate gr. 40 Strontium bromid gr. 40 Lithium bromid gr. 40 Passion flower (green root)..gr. 80 Henbane (green leaves) gr. 16 Cannabis indica gr. 8 Sophol. This is a name applied to a combina- tion of formaldehyde-nucleinic acid and silver, containing 20% of the latter. It is a yellowish white powder. This name is also applied to an easily melting powder which is recommended for external use as an antirheumatic in place of mesotan. i Sorbefacin. This is described as a soft, plastic sur- gical dressing containing menthol, thy- mol and boracic acid. Soson. This is described as pure, unaltered meat albumen in powder form. It is odorless and tasteless and is said to con- tain 98^% albumen. It is used as a nutrient. Sourwood Compound. (Diuretic Elixir.) (131) The formula is given as follows : Oxydendron arboreum gr. 8 Hydrangea arborescens gr. 64 Eupatorium purp gr. 64 Polytrichum junip gr. 64 Eryngium yuccaefol gr. yz Stigmata maidis gr. 32 Tr. apis mellif drops 2 Lithii benzoas gr. 24 Spiritus juniperi fl.dr. 4 Each fluidounce represents 30 grains of the fresh (green) drugs in the above proportions, and 3 grains of benzoate of lithia. Sozal. This is chemically aluminum para- phenolsulfonate. It is in brownish crys- tals which are of a faint carbolic odor and of a strong astringent taste. It is soluble in water, alcohol and glycerin. It is used in 1% solutions as an injection in tuberculous ulcers, suppurations and cystitis. Sozoiodol. There are several salts of sozoidolic (or diiodoparaphenolsulfonic) acid, but the sodium salt is commonly dispensed under the name sozoiodol. It is in white odorless crystals, soluble in 12 parts wa- ter and in alcohol or glycerin on warm- ing. An internal and external antiseptic in infectious diarrhea, phthisis, diabetes, wounds, diphtheria, soft chancre, para- sitic skin diseases, etc. Dose: 15 to 45 grains daily. Exter- nally it is used in a 1 to 8% solution or 10 to 25% dusting powder or ointment. PROPRIETARY AND SYNTHETIC REMEDIES. 849 Sozoiodolic acid is also used in 2 to 3% aqueous solution as an antiseptic. There are also mercury, potassium, zinc, lithium, barium, manganese and lead compounds of sozoiodol. Spasmotin. (Sphacelotoxin.) This is a poisonous principle extracted from ergot. It is yellow, amorphous powder soluble in alcohol and ether, and is used as a hemostatic and emmena- gogue in amenorrhea, dysmenorrhea, etc., in doses of H to iH grains. Sparteine Sulfate. This is an alkaloidal salt from Saro- thamnus scoparius. It is in colorless, odorless, somewhat bitter, slightly hy- groscopic crystals, easily soluble in wa- ter or alcohol. It is a heart tonic like digitalin. Dose : Single, % to Ya grain ; daily, ^ to 1^ grains in pills or powders. Maximum dose, single, Y* grain; daily, 1Y2 grains. Specific Medicines. (118) The manufacturers state that they have become convinced "that ordinary fluid and solid extracts are crude and imperfect." They began a systematic study of each plant, and the perfected result was named a Specific Medicine (not a specific tincture), to distinguish it from all other preparations, for it specifically represents the active princi- ples of the drug yielding it. The process of manufacture is not given, except to state that almost all of them are liquid and are made from crude drugs — i. e., plant parts. Each fluidounce is stated to represent 480 grains (1 troy ounce) of crude material (unless otherwise stated). The above remarks apply to most of these medi- cines. The following are exceptions: Acid Hydrochloric Dilute. — A solu- tion of chemically pure hydrochloric acid. Acid Carbolic— A solution of pure crystallized carbolic acid in glycerin. Acid Sulfurous. — This is alcohol, sp. gr. 0.820, saturated with sulfurous acid gas. Cantharis. — An alcoholic solution of the characteristic principles of cantha- rides. Carbo Veg. — A trituration with milk sugar, selected powdered wood charcoal being used. Cinnamon. — An alcoholic solution of the oil of Ceylon cinnamon. Cuprum. — Made the same as Rade- macher's tincture of acetate of copper. Elaterium. — Each pint represents 60 grains of elaterin. Ferri Aceticus. — Made of the proper salts and pure wine vinegar, according to Rademacher's original formuta. Phosphorus. — A saturated solution of phosphorus in alcohol. Podophyllin Triturated. — Made of true dark podophyllin (precipitated in pure water) and pure milk sugar. Sodium Sulfite and Phosphate. — These are not the commercial crystal- lized salts. Each preparation is mostly free from water, and much stronger than the commercial crystallized salts. Tela Araneae. — An alcoholic tincture of house spider web. These explanations are taken from the manufacturers' catalog. Spencer's Chloramine Pastilles. (221) These are stated to contain ammonium muriate as the chief ingredient. They are used for hoarseness, sore throat, bronchitis, and cough. Spermine-Krieger. This is a sterilized solution prepared from various glands of healthy young animals. It has been recommended for various diseases. The dose is 3 to 6 minims, which may also be administered hypodermically. The dose is to be in- creased by 1 minim per day. It is mar- keted in 1 -gram flasks. Spermin-Marpman. This is described as a solution of the soluble substances of the fresh testicles of the steer. It is given by the mouth in 850 THE STANDARD FORMULARY doses of 5 to 20 drops 2 or 3 times a day. Spermine-Poehl. This is the hydrochlorid of a base ex- isting in the testicles of animals. It is marketed in the form of a 2% solution, which is used hypodermically in doses of 15 minims daily or every other day for nervous disorders accompanied by anemia (neurasthenia, angina pectoris, locomotor ataxia, etc.). It is also put up in the form of an elixir. Sphygmogenin. This is a name given to the active constituent of the suprarenal capsules. Spinatica. This is described as a sovereign cerebro-spinal stimulant, 10 minims of which contain 1/300 grain of phosphorus and proportional amounts of "nux," ignatia, columbo, gentian, quassia, cin- chona and aromatics. Spinol. (Spino-Ferrinum.) This is described as a form of or- ganic iron derived from the vegetable spinach. It is put up in a dry form, which is an odorless, almost tasteless powder, and a syrupy form (spinolum saccharatum). Spiroform. This is a white, crystalline powder, insoluble in water but readily soluble in alcohol and other solvents. It is odor- less and almost tasteless. It is recom- mended as an antirheumatic, analgesic and uric acid solvent. The dose is 7^2 to 15 grains 3 to 5 times daily. Spirosal. This is the salicylic acid ester of monoglycol. It is an almost colorless and odorless oily liquid. It is readily soluble in alcohol, ether and chloroform. It is applied 2 or 3 times daily in cases of rheumatism. It is said to be non- irritant and to be readily absorbed by the system. Stafford's Boro-Fluorine. This is the analysis by Drs. Endemann and Saarbach, according to the manu- facturers : Boric acid, 19^4%, sodium fluoride, 5^4%, benzoic acid, 3%, for- maldehyde, l />%, gum vehicle (dextrin and dextrose), 42%, water, 29^2%. It is used as a germicide. Stagnin. This is a hemostatic substance ob- tained by the extraction of the spleen of horses. The product obtained is a yel- lowish brown powder which is marketed in the form of an aqueous solution. It is used mainly in gynecological prac- tice. The dose is 15 to 45 minims daily. Steagine. This is a compound of zinc stearate and paraffin which has been introduced into France for the treatment of skin diseases. Stearate of Zinc Compound. (121) This is put up with various combina- tions, viz., boric acid, peru balsam, men- thol, tar, acetanilid, resorcin, aristol, etc. Stearns' Wine. (187) This is a medicated wine, each fluid- ounce of which is stated to contain 4 grains of alcoholic extract of fresh cod liver (made from fresh livers received in alcohol and containing their full amount of oil) and 4 grains of pepton- ate of iron, in a menstruum containing I5 J A% of alcohol. The product con- tains about 34% of oily extractives. It has been introduced as a substitute for cod liver oil. The dose is 1 tablespoon- ful 3 or 4* times a day. Steresol. Shellac parts 270 Benzoin parts 10 Tolu balsam parts 10 Phenol parts 10 Oil of cinnamon parts 6 Saccharin parts 6 Alcohol, to make parts 1000 This is recommended by Berlioz as an antiseptic skin varnish. PROPRIETARY AND SYNTHETIC REMEDIES. 851 Stomalix. Each tablespoonful is stated to con- tain Fluid ext. bitter orange peel. . .gr. 3 Fluid ext. condurango gr. 3 Fluid ext. cinchona gr. 3 Pure pepsin _ gr. 4 Bismone (colloidal bismuth oxide) gr. 4 "Citrate soda ammoniated" gr. 5 Stomatol. This is an antiseptic and preservative said to consist of terpineol, soap, alco- hol, glycerin, water and aromatics. Stomosan. This is stated to contain methylamine phosphate and is used as a gall-stone preventive. Stonebraker's Liniment. The following formula is taken from the patent office reports: Alcohol gal. i l / 2 Turpentine gal. Y\ Oil of origanum lb. Yz Capsicum oz. I Barbadoes tar oz. 4 Ammonia lb. 2 X /^ Linseed oil oz. 10 Oil of amber oz. 5 Oil of juniper oz. 5 Seneca oil oz. 1^ Castile soap lb. i l / 2 Stonebraker's Pain Killer. The following formula is taken from the patent office reports: i< Peru balsam lb. i J A Venice turpentine oz. 6^2 Olive oil oz. 1^2 Sulfuric ether lb. 4V5 Camphor oz. 8 Laudanum oz. 5 Tincture of capsicum oz. 8^ Tincture of myrrh oz. 8}4 Stovaine. Chemically this is amylene hydro- chlorid. It crystallizes in small, brilliant scales, is very soluble in water, methyl alcohol, or acetic ether, but requires 5 parts of absolute alcohol for solution and is only slightly soluble in ether or acetone. It is quite stable and its solu- tions may be sterilized at 115 C. with- out decomposition. It is incompatible with alkalies and all alkaloidal reagents. 54 It is used as a local anesthetic in 4 to 10% solutions in place of cocaine. It is only y 3 to l / 2 as toxic as the latter. The dose internally is 1/30 grain. It is ap- plied locally to the eye in 4% solution, in laryngology, in 5 to 10% solutions, and hypodermically in 1% solution. It is sold in the form of powder, solution, triturates and pastilles. Streptocol. This is a soluble preparation stated to contain 60% of cresol. Strzyzowski's Mixture. This is a preparation of iron pyro- phosphate, quinine hydrochlorid and so- dium bromid. The dose is a teaspoonful 2 or 3 times daily after the principal meals. Strophanthin. This is a glucoside from Strophanthus hispidus. It is a white crystalline pow- der, soluble in water and alcohol. It is used as a heart tonic in place of digi- talis. Dose: 1/300-1/200-1/120 grain. The physiological antidoes are aconite and veratrum viride. Stuart's Dyspepsia Tablets. According to the manufacturers, these are composed of vegetable and fruit es- sences, pure concentrated tincture of hydrastis, lactose (extracted from milk) [i. e., milk suger], "nux," pure aseptic pepsin, bismuth, and flavored with gin- ger. Elsewhere in the same pamphlet, it is stated that they are composed of fruit salts, vegetable essences,, pepsin and bismuth; and again, "composed of vegetable and fruit essences, pure pep- sin, golden seal, ginger and the diges- tive acids"; and also, "composed of harmless digestive principles, vegetable essences, pepsin and golden seal." Stuart's Calcium Wafers. These are stated to contain "in con- centrated form the newly discovered preparation from sulphur (calcium sul- phide), golden seal, quassia, eucalyptus. belladonna, and the vegetable alteratives and laxatives." THE STANDARD FORMULARY Stypticin. (Cotarnine Hydrochloric!.) (130) Cotarnine is an oxidation product of narcotine, one of the alkaloids of opium. Stypticin is a yellow, crystalline powder, soluble in water and in alcohol. It is a hemostatic and uterine sedative, and is recommended for all forms of uterine hemorrhage. It is also used in bleeding from the bladder, from the nose, after extraction of teeth, etc. The dose is H grain 4 or 5 times daily. It may be given hypodermically 2 cc. of a 10% so- lution. Styptol. (Cotarnine Phthalate.) (109) This is yellow, microcrystalline pow- der which is freely soluble in water. Its action resembles that of stypticin. Com- pounds with phthalic acid are said to have especial hemostatic properties. It has been recommended for uterine hem- orrhages in doses of 1 grain 3 to 5 times daily. It is also used externally as a dusting powder for bleeding wounds. Styracol. (Guaiacol Cinnamate.) This is in colorless, odorless and tasteless crystalline needles, insoluble in water but readily soluble in alcohol, ace- tone or chloroform. It contains 55% of guaiacol which is split off by the action of alkalies. It is claimed to be an in- testinal antiseptic and to combine the antituberculous properties of guaiacol and cinnamic acid. It is said to liberate in the intestinal canal as much as 857© of its guaiacol content. It is recom- mended for the initial stage of phthisis, chronic enteritis, and intestinal distur- bances in general. The dose is 15 grains 3 or 4 times a day. Subcutine. (Anesthesin Paraphenol Sulfonate.) This has the advantage over anesthe- sin of greater solubility so that it can be used hypodermically. It is a white pow- der soluble in 100 parts of water. It is used subcutaneously as a 1% solution to produce local anesthesia. Subeston. This is a basic diacetate of aluminum which is used as an antiseptic, astringent and deodorant for infected wounds. Sublamine. (178) This is a compound of 1 molecule of mercuric sulfate and 2 molecules of ethylene-diamine. It is in white needles which are very soluble in water, soluble in 10 parts of glycerin, and sparingly soluble in alcohol. It contains about 44% of mercury, it does not precipitate albumen, it is incompatible with sodium chlorid, and it should not be exposed to the air. It is a disinfectant similar to mercuric chlorid, over which it has the advantage of being non-irritating, more penetrating and readily soluble. It is used in a 1 :iooo solution for skin disin- fection and 1 oooo solution for irriga- tions of the bladder, etc. Succus Alterans. (Alterative Juice.) (117) This is described by the manufactur- ers as the preserved fresh juices of Stillingia sylvatica. Smilax sarsaparilla, Phytolacca decandra. Lappa minor, and Xanthoxylum carolinianum. Sucramine. This is the ammonium compound of saccharin. Sucrol. See Dulcin. Sulfanilic Acid. This is in small, white crystals which are soluble in 112 parts of water, less soluble in alcohol, and insoluble in chloroform and ether. It is used as a test (Ehrlich's) for typhoid fever. Sulfosalicylic Acid. (Salicylsulfonic Acid.) This is in white crystals readily solu- ble in alcohol or water. It is used as a test for albumin in urine. Sulfosot. This is chemically potassium-creosote- sulfonate. It is a brown, syrupy liquid, freely soluble in water. It is marketed PROPRIETARY AND SYNTHETIC REMEDIES. 853 as a 10% syrup which is palatable, hav- ing no taste of creosote. The dose is I to 4 fluidrams. Sulfogen. This is stated to contain 75 grains of echinacea root, 5 grains of thuja, io grains of hydrated chloral, and 40 grains of magnesium sulfate to each fluidounce, with aromatics. Sulf ogenol. This is a clear, syrupy liquid of a red brown color and a neutral reaction. It is soluble in water, alcohol or ether. It is a similar product to ichthyol, an oil being obtained from bituminous shale, which is then treated with sulfur. Sulfur Compound Tablets. (Formula of Q. C. Smith, M. D.) These are put up by various firms. Each is stated to contain Sulfur gr. 5 Cream of tartar gr. 2 Extract of ipecac gr. 1/100 Extract of capsicum gr. 1/500 Arsenous acid gr. 1/1000 Calcium sulfid gr. 1/8 Sometimes the calcium sulfid is re- placed by 1/16 grain of sodium ben- zoate. Sulphaminol. ,(Thio-oxy-diphenyla- mine.) This is a pale yellow, odorless and tasteless powder, insoluble in water, sol- uble in alcohol or alkaline solutions. It is said to be a non-poisonous antiseptic recommended as a substitute for iodo- form. The dose internally is 3 to 5 grains 3 times a day. Sulphydrol. This is stated to be an alkaline sulfur solution containing "sulphur (pure), grs. i%" "iron (sulph.), grs. %," and "quinine (sulph.), grs. M" Sulphoguaiacin. This is chemically quinine sulfoguaia- colate. It is prepared by treating guaia- col with sulfuric acid to form guaiacol- sulfonic acid from which the barium salt is formed and then the quinine salt. The product is in small, yellow crystals, soluble in water or alcohol. It is used in phthisis, intestinal catarrh, etc. The dose is 5 to 15 grains 3 times a day. Sulphonal. (Diethylsulfondimethyl- methane.) This is a white, odorless and tasteless, crystalline powder. It is only sparingly soluble in water but is more freely solu- ble in alcohol, ether or chloroform. It is a hypnotic which seems to have no untoward effects. It is given in doses of 15 to 30 grains, which should be dis- solved in some hot liquid such as tea, soup, milk, etc. Sulphonethylmethane. This is the U. S. P. name for Trional, which see. Sulphonmethane. This is the U. S. P. name for Sulpho- nal, which see. Sulzburger Fluss Tinktur. This is stated (by Hager) to contain bitter and aromatic substances, including some aloes. Sundheds Salt. (Health Salt.) This is an old Danish proprietary ar- ticle, which is now put up under these and other formulas: I. Sodium bicarbonate parts 7 Sugar parts 2 Magnesium carbonate part 1 II. Magnesium carbonate part 1 Exsiccated magnesium sul- fate parts 2 Sodium bicarbonate parts 50 Peppermint-oil sugar parts 25 Suprarenal Liquid. (159) This is an aqueous extract of suprere- nal glands, preserved with 8/10% of chloretone. Each cc. of solution repre- sents 1 g. of the fresh glands. The preparation is used in the undiluted form for spraying mucous membranes. Suprarenalin. (14) This is the active principle of the su- prarenal gland. It is a finely crystalline, light yellow, odorless and slightly bitter substance. It is only slightly soluble in cold water or alcohol but readilv soluble 854 THE STANDARD FORMULARY in acids and fixed alkalies, insoluble in ether. It is seldom used in its undiluted state but mostly as the solution, oint- ment or triturates. Suprarenalin Solution is stated to be a 1:1000 solution of suprarenalin sulfite in normal salt solution, free from other preservatives. It is used locally as a hemostatic and is given internally as a heart stimulant. Internally it is admin- istered in doses of 5 to 30 minims every 2 or 3 hours, hypodermically 1 to 15 drops. Locally it is applied in strengths ranging from 1 : 15000 to 1 :iooo. Suprarenalin Ointment contains 1/10% (1:1000) of suprarenalin dissolved in a petrolatum base. It is recommended for application to mucous membranes, such as the eye or nose. The action is said to be slower but more lasting than that of the solution. Suprarenalin Triturates are tablets of suparenalin, sugar and boric acid, weigh- ing V* grain, containing such a propor- tion of suprarenalin that when a tablet is dissolved in 15 minims of water, a I :iooo solution will be obtained. These are used for the extemporaneous prepa- ration of the solution. It is marketed in vials containing 20 tablets. Suprarenin. This is a 1 :iooo solution (in the form of chlorid) of the active principle of the suprarenal glands, which is made in Germany. Suprarenin Borate. This is put up in tablet form, each tab- let containing .00013 g. suprarenin bor- ate, .009 g. sodium chlorid, and .01 g. of cocaine. One tablet dissolved in 1 cc. of sterilized water yields a solution which is effective as an obtunder of pain in the extraction of teeth. Surgeon's Antiseptic Oil. This is stated to contain iodoform, glycerin, camphor, capsicum, carbolic acid, and stimulating liquids. Svapnia. This is a scale preparation of opium, described as containing "the anodyne and soporific alkaloids codeia, narceia, and morphia; excludes the poisonous and convulsive alkaloids thebaine, nar- cotine and papaverine." Sycose. This is chemically orthobenzoicacid sulfinid, and is a purified form of sac- charin which is official in the U. S. P. under the name benzosulphinide. It is a white, crystalline powder, sparingly soluble in water, readily soluble in alco- hol or ether. It possesses a sweetness estimated as being 550 times that of sugar. Symphorol. (Nasrol.) This is the generic name of salts of caffeine-sulfonic acid. Sodium, lithium and strontium salts are employed, usu- ally the first mentioned. They are bit- ter, crystalline compounds, slightly solu- ble in cold water. These compounds are used as diuretics, not affecting the vas- cular nervous system or blood pressure. Dose: 8 to 10 grains several times daily, in capsules. Syrocolin. This is the name given to a solution of potassium sulfoguaiacolate made in Basle, Switzerland. Syrquin. (223) This is described as an aromatic syrup of yerba santa recommended for dis- guising the bitter taste of quinine. Syrup of Acid Glycerophosphates. See Glycerophosphates Syrup and Tablets. Syrup Antiepischesis. (192) This is described as a combination of figs, cascara sagrada. and Alexandria senna. Syrup Cannabis Componnd. Each fluidounce is stated to be equal to 7^ grains of cannabis indica, Vz grain of heroin hydrochlorid, 4 minims of chloroform, 7J/2 grains of lobelia, % grain of tartar emetic, 10% of alcohol, and aromatics. PROPRIETARY AND SYNTHETIC REMEDIES. 855 Syrup Cocillana Compound. (159; Each fluidram is stated to contain Tincture euphorbia piluli- fera m. 15 Syrup lactucarium m. 15 Tincture cocillana m. 5 Syrup squill compound. .. .m. 3 Cascarin gr. I . Heroin hydrochlorid gr. 1/2 Menthol gr. 1/10 Syrup Codeine Co. See Bell's Syrup Codeine Co. Syrup Codeine Phosphate, Compound. (143) Each fluidram is stated to contain Codeine phosphate gr. V 6 Eucalyptus gr. J /z Ipecac gr. y± Terpin hydrate, q. s. to saturate. Syrup of Glycerophosphates. See Glycerophosphates Syrup. Syrup of Glycerophosphates, Com- pound Acid. See Glycerophosphates Syrup and Tablets (Huxley's). Syrup of Histosan. See Histosan.- Syrup of Hypophosphite Comp. See McArthur's Syrup of Hypophos- phites Comp. Syrup Iron Chloride(Weld.) (159) Each fluidounce is stated to represent 40 drops of U. S. P. tincture of iron chlorid. Syrup Lactopeptine with Phosphates. (Syr. Lactopept. Comp.) Each fluidounce is stated to contain 32 grains of lactopeptine and 8 grains each of the phosphates of lime, iron, soda and potash. Syrup Laxatans. Each fluidram is stated to contain rhamnus frangula, 10 grains ; cassia acu- tifolia, 10 grains; juglans cinerea, 10 grains; hyoscyamus niger, 2 grains, and aromatics, q. s. Syrup Manganum Comp. (Syr. Man- gani Comp.) (180) This syrup is stated to contain 5 grains of the combined hypophosphites of manganese, lime, soda and iron, with 1/16 grain of quinine and 1/64 grain of strychnine to the fluidram. Syrup Phospho-Chloride Iron (180) Each dessertspoonful is stated to con- tain 10 drops of tincture of iron with phosphorus, glycerin, lime juice, and aromatics. Syrup Phytolacca Comp. (212) Each fluidounce is stated to contain Phytolacca decandra gr. 48 Stillingia sylvatica gr. 48 Lappa major gr. 48 Corydalis formosa gr. 48 Cascara sagrada gr. 16 Xanthoxylum fraxineum gr. 16 Potassium iodid .gr. 16 Syrup Pinus Alba Comp. See Pinus Alba Compound. Syrup of Potassium Hypophosphite. According to Hager, this is composed of Potassium hypophosphite ...part 1 Lime water parts 6 Water parts 30 Sugar parts 64 Cochineal, to color light red. Syrup Pulmonic Comp. Mills. (215) Each fluidram is stated to contain Dover's powder gr. 2 Ammonium muriate gr. 2 Fluid extract sanguinaria m. 2 Sodium sulfate gr. 10 Cascara sagrada gr. 10 Syrup figs, to make fl.dr. 1 Syrupus Roborans. This is stated to contain in each fluid- ounce 1Y2 grains each of potassium and iron hypophosphites, I grain each of lime and manganese hypophosphites, ¥$ grain of quinine hypophosphite and 1/16 grain of strychnine hypophosphite. Syrup Sanguinaria Comp. with Co- deine and Terebene. (194) Each fluidram is stated to contain 24 grains of wild cherry bark, 16 grains of white pine bark, 4 grains of blood root, 2 minims terebene, and 1 grain of co- deine. Syrup Seven Hypophosphites. (132) Each fluidounce is stated to represent Calcium hypophosphite gr. 4 Potassium hypophosphite ...gr. 4 Iron hypophosphite gr. 2 856 THE STANDARD FORMULARY Manganese hypophosphite . .gr. I Quinine hypophosphite gr. I Sodium hypophosphite gr. l / 2 Strychnine hypophosphite ...gr. 1/16 Syrup Six Hypophosphites. (198) Each fluidounce is stated to contain potassium and iron hypophosphites, each, I l / 2 grains ; lime and manganese hypo- phosphites, each, 1 grain ; quinine hyop- phosphites, 7/16 grain, and strychnine hypophosphite, 1/16 grain. Tabsules and Tabsoids. The first are gelatin capsules, the sec- ond gelatin globules, of "methylene blue compound" containing the methylene blue in the form of a tablet. Taka-Diastase. (159) This is a ferment obtained by the ac- tion of a fungus upon steamed rice. It occurs as a yellowish white powder which, like malt diastase, has the prop- erty of converting starch into sugar. It is incompatible with strong alcohol, al- kalies and strong acids. It is used to assist the functions of the stomach in amylaceous dyspepsia, the dose being 2 to 5 grains. It is also put up in tablet and liquid forms. Tachiool. (Silver Fluorid.) This is in yellow, deliquescent cry- stalline conglomerations, soluble in wa- ter, and darkening on exposure to light. It is a powerful antiseptic, at the same time being apparently much less toxic than other antiseptics. A solution of 1 in 150,000 was found to kill all pyogemic organisms in a minute ; a solution of 1 in 200,000 was sufficient to kill typhoid bacilli in 1 minute; and a solution of 1 in 1000 was sufficient to kill anthrax spores in 20 or 30 minutes, after these had resisted steam for 15 minutes. Tamar Indien. According to the Repert. de Pharm., this is the composition : Tamarind pulp, 450, sugar, 40, sugar of milk, 60, glyce- rin, 50; mix, evaporate to syrupy con- sistence and add powdered senna leaves, 50, powdered anise, 10, essence of lemon, 3, tartaric acid, 3. After mixing, divide the mass into troches, and roll these in a mixture of cream of tartar, 5, sugar, 35, sugar of milk, 35, tragacanth, 2, tartaric acid, 2, red saunders, 25. Finally dry the troches and wrap in tin foil. Tanichthol Suppositories. (141) These are put up in two forms, Nos. 1 and 2. No. 1 contain % grain each of extracts of belladonna, witch hazel and stramonium, 24 grain of phenol, 1 grain of ichthyol, 2 l / 2 grains of tannic acid, and 1 grain of opium. No. 2 are the same except that they contain no opium. Tannal. Ordinary tannal is aluminum tannate, the soluble variety being aluminum tan- notartrate. This is a yellowish white powder, soluble in 2 parts of water. It is used as an astringent, particularly for catarrhal troubles of the nose and throat, in the form of 1 to 5% solutions. Tannalbin. (109) This is a modified tannin albuminate, obtained by heating the latter, after pre- cipitation, for 6 hours to 126 C. It is a yellowish, tasteless, odorless powder, containing 50% tannin, insoluble in wa- ter or alcohol. It is used as an intestinal astringent in acute and chronic diarrheas, being without action on the mouth or stomach, and being gradually decomposed in the intestines into tannin and an inert albu- minoid. Dose: 15 grains 2 to 4 times daily, usually in powders. Tannalborin. This is a grayish brown powder con- sisting of a compound of aluminium subgallate with 10% of sodium borate. It is a grayish brown powder, only spar- ingly soluble in water or alcohol, and used mainly in the treatment of the diarrhea of fowls and pigs. The dose is a teaspoonful to a tablespoonful. Tannigen. (Diacetyltannin.) This is a yellowish gray, slightly hy- groscopic, odorless, tasteless powder, soluble in alcohol and in solutions of so- dium phosphate, carbonate or borate, PROPRIETARY AND SYNTHETIC REMEDIES. 857 slightly soluble in hot water and ether but insoluble in cold water. It is incom- patible with acids and alkalies. It should not be exposed to heat and moisture. Used as an astringent in chronic diar- rhea, dysentery, etc. It is not decom- posed in the stomach but passes on to the intestines, where it is broken up by the alkaline fluid into its constituents. Dose : 3 to 8 grains 4 times per day. Tannisol. (Methylditannin.) This is a condensation product of for- maldehyde and tannin. It is a reddish brown, odorless and tasteless powder, in- soluble in water or ether, soluble in alco- hol or weak alkaline or alkaline carbon- ate solutions. It is recommended in in- testinal catarrh and severe diarrheas in doses of TV2 grains and upwards. It is also used externally as a dusting powder and in ointments. Tannobromine. This is obtained by the action of for- maldehyde upon dibromtannin. It is a reddish or yellowish gray powder con- taining 25% of bromin. It is only slight- ly soluble in water but dissolves freely in alkaline solutions. The aqueous solu- tion is colored blue by the addition of iron chlorid. It is employed as a nerve sedative in place of alkali bromids. Tannoform. (Methylenditannin.) (130) This is a condensation product of tan- nic acid and formaldehyde. It occurs as a voluminous reddish powder, odorless and tasteless, and is soluble in alkaline solutions but not in water. It is a drying antiseptic in hyperid- rosis, bromidrosis, soft chancre, ozena, etc. Used either in the undiluted state or a 25 to 50% solution. The dose in- ternally is 4 to 8 grains for chronic in- testinal catarrh. Tannopine. (Tannone.) This is a condensation product of tan- nin with hexamethylentetramine. It is a fine, light, brownish, odorless, tasteless and non-hygroscopic powder containing 87% of tannin and 13% of hexamethy- lenetetramine. It is insoluble in water, weak acids, alcohol, chloroform, or ether but slowly soluble in dilute alkalies. When ingested it passes the stomach un- changed but in the intestines is decom- posed into its constituents, hence it is a valuable astringent and antiseptic for use in various intestinal disorders. Dose : 5 to 8 grains to 15 grains for adults, 4 times a day. Tanosol. Creosote Tannate— Creosal.) This is a dark brown, amorphous pow- der, very hygroscopic, and hence is sold in aqueous solution or in pills. The for- mer contains 30 grains of tanosol and 20 grains of creosote in each fluidounce, while each of the pills contain 5 grains of tanosol and 3 grains of creosote. This is recommended as an easily di- gestible compound of creosote. Like all creosote compounds, it is useful princi- pally in tuberculosis of the lungs, bron- chitis, etc. The usual dose of the solu- tion is one tablespoonful 3 times daily. Tannothymol. This is the name given to a condensa- tion product of formaldehyde, thymol and tannin. It is a white, tasteless pow- der, soluble in alcohol and alkaline solu- tions. It is recommended in cases of severe diarrhea in doses of 7^ grains, repeated several times a day. Tanphenyform. (212) This is said to be a mixture composed of 63.9% of tannin albuminate (prac- tically equivalent to 35 of tannin), 8.3% of hexamethylenetetramine, and 27.8% of salol. It is a moist, brown powder, of a slight aromatic odor and taste. It is used in various intestinal disorders in doses of 10 to 30 grains 3 to 5 times a day. It is supplied in the form of a powder, also in 5 and 10-grain capsules. Tartarlithine. This is described as an effervescent salt, the lithium analogue of cream of tartar (*. c, it is lithium bitartrate), containing none of the additional alka- line salts common to the granular effer- vescent preparations. 858 THE STANDARD FORMULARY Tebecin. This is an antitubercular substance ob- tained by evaporating the blood coagula of immunized calves and horses on a water bath at not above 35° C. When evaporated to a doughy consistence it is then dried over sulfuric acid in a vac- uum. It is given in doses of 4 g. daily. Teething Necklaces. According to Wittstein and others, these consist generally of strips of cot- ton cloth impregnated with sulfur and encased in a velvet covering, the whole made into the form of a narrow band which is to go around the child's neck. According to the manufacturers, these are supposed to act electrically or mag- netically. Tenaline. This is a preparation of areca nut containing the alkaloids arecaine, are- caidine and guvacine but not the poison- ous principle arecoline. It is used as a vermifuge for dogs and cats; no cathar- tic is said to be necessary. Terebene. This is a mobile liquid of an odor similar to that of turpentine, sparingly soluble in water, readily in alcohol. Ap- plied externally as an antiseptic for di- verse wounds, with 20 parts of water, and for antiseptic inhalations in phthisis, bronchial catarrh, bronchorrhcea, and bronchitis. It may be utilized internally whenever turpentine is indicated, being much more agreeable than the latter. Dose : 4 to 6 drops, gradually increased, 3 times daily. Teremorrhu. This is described as a pleasant and palatable preparation of pure terebene and cod liver oil. Terp-Heroin. This is stated to contain 2 grains of terpin hydrate and 1/24 grain of heroin to the dram in a vehicle of prunus sero- tina and glycerin. Terpinoids. (89) These are gelatin pearls, each contain- ing Terpinol m. 3 Eucalyptol m. 1 Creosote m. 1 Heroin gr. 1/40 Terrol. This is said to be a paraffin product which in warm weather is a viscid, yel- lowish oil, but in cold weather resem- bles white petrolatum. It is odorless and tasteless ; it is used as an ointment vehicle. Testaden. (109) This is the powdered extract of the testicular juice of animals. It is used in impotency, neurasthenia and spinal irritation. The dose is 15 grains 3 or 4 times a day. It is supplied in the form of powder and as 4-grain tablets. Testine. This is described as the sterilized ex- tract of the testes of the ram and the bull. Teston. This is a preparation made from the testicles of the ox Tetraethylammonium Hydroxid. This occurs in 10% solution," and is a colorless, alkaline, bitter liquid. It is a solvent of uric acid; used in rheuma- tism, gout, etc. Dose: 10 to 20 minims 3 times daily, well diluted. When used by injection, the dose is 1 or 2 minims, 4 or 5 times daily. Tetronal. Diethylsulfondiethyl- methane.) This is in colorless, crystalline scales, sparingly soluble in water and alcohol. It is used as a hypnotic in doses of IS to 30 grains. Thalline Sulfate. This is in white needles or crystalline powder of a cumarin-like odor, very sol- uble in water. It turns brown on ex- posure to light. It is an antiseptic and PROPRIETARY AND SYNTHETIC REMEDIES. 859 antipyretic, to be used in typhoid and malarial fevers, typhus, etc., in doses of 3 to 8 grains. Theine. This is the same as caffeine. Theobromine. This is a base occurring in Theobroma cacao, Kola acuminata, etc., but is now prepared s} r nthetically ; chemically it is dimethylxanthine. It is a white, cry- stalline, odorless and bitterish powder. It is almost insoluble in cold water or chloroform, but readily soluble in hot alcohol, or in ether. It forms salts with acids. Its uses are similar to caffeine but it does not act so powerfully on the central nervous system. It is rec- ommended as a diuretic in dropsy, etc., but the great obstacle to its employment is its insolubility so that it is generally preferred in the form of some soluble compound. The dose is 5 to 8 grains. Theobromine and Lithium Benzoate. See Uropherin-B. Theobromine and Lithium Salicylate. See Uropherin-S. Theobromine-Sodium Acetate. See Agurin. Theobromine-Sodium Citrate. See Urocitral. Theobromine-Sodium Salicylate. See Diuretin. Theocin. (Dimethylxanthine.) This is chemically the same as theo- phyllin, the latter name being applied to the base when derived from tea, the former when prepared synthetically. It is also isomeric with theobromine. It is a white, odorless, bitterish, crystalline powder, moderately soluble in water, sparingly soluble in alcohol, sparingly in ether. It is a powerful diuretic in doses of 3 to 5 grains 2 or 3 times a day. It is recommended for cardiac affec- tions, nephritis, dropsy, etc. Theocine-Sodium Acetate. (Soluble Theocin.) This is a readily soluble compound of sodium acetate and theocin-sodium. It contains 60% of theocin, is soluble in 23 parts of water, is insoluble in alco- hol and ether, and is a white crystalline powder. It has the diuretic properties of theocin combined with those of so- dium acetate. It is more soluble and is therefore more readily absorbed and more readily tolerated than theocin. It is recommended in cardiac affections, nephritis, dropsy, etc., in doses of 3 to 5 grains 4 times daily. Theocin-Sodium Salicylate. This is an analogous to theocin-so- dium acetate and is given in the same doses in renal affections. Theolactine. (222) This is a double salt of theobromine- sodium and sodium lactate, and forms a fine white powder, containing about 57% of theobromine. It is very solu- ble in water and its solutions have a bitterish and slightly alkaline taste. It must be protected against light and moisture. It is given in doses of 15 grains 3 or 4' times a day. Theonacet. This is another name for theobro- mine-sodium acetate, which see. Theophyllin. This is a base found in small amount in tea. It is prepared synthetically un- der the name theocin, which see. Thephorin. (98) This is a double salt of theobromine and sodium formate. It is a white pow- der, soluble in 10 parts of water. It contains 62^% of theobromine and is administered in the same manner and for the same purposes as diuretin. Therapogen. According to the Pharm. Ztg., this is a water-soluble compound of various terpenes with members of the naph- thalin group. It forms an agreeably- odorous, oily, saponaceous liquid which is disinfectant and deodorant. In 3% solutions it is used as a wash for wounds. 860 THE STANDARD FORMULARY Thermiol. This is a 25% solution of sodium phenol-propiolate which is used in 1 to 3% solutions as an inhalant for dis- eases of the air passages. Thermodin. (Ph.enacetin-TJreth.ane.) (130) This is in colorless, odorless and tasteless crystals. It is only very spar- ingly soluble in water. It is an anal- gesic, antipyretic and antiseptic. It is recommended as a mild and reliable antipyretic in typhoid fever, pneumonia, influenza, etc., in doses of 5 to 10 grains. The analgesic dose is 15 to 20 grains. Thermol. (116) This is described as acetsalicylphen- etidin. It is a white, odorless, tasteless, crystalline powder, sparingly soluble in water, readily soluble in alcohol. It is an antipyretic and analgesic in doses of 15 grains. Thermol-Salicylate Comp. Tablets. These are stated to contain thermol, colchicine, and salicylic acid. Thermofuge. (159) This is described as an antiphlogistic preparation composed of aluminium sili- cate, glycerin, boric acid, menthol, thy- mol, oil of eucalyptus, and ammonium iodid. It is applied externally for the reduction of inflammations. Thial. This is said to be chemically formin oxymethylsulfonate. It is a white, odor- less powder, readily soluble in water. It is used as a vulnerary in Y 2 to 1% solutions, as a wash and for irrigations in Y+ to l / 2 % solutions, and for disin- fecting cuspidors in 2% solutions. Thiderol. This is a syrup preparation contain- ing 2% of guaiacol. It is used in pul- monary and laryngeal affections in doses of a teaspoonful 3 or 4 times a day. Thieucalyptol. This is another name for Sanosin. which see. Thigenol. (98) This is described as the sodium salt of a sulfonic acid of a synthetic sulfo oil, a soluble, odorless sulfur compound. It is a thick, nearly odorless liquid, sol- uble in water, alcohol and glycerin, and contains 10% of sulfur. It is used in skin and female diseases. Internally the dose is 3 to 10 grains 3 times daily. Thilanin. This is described as a sulfuretted wool fat containing 3% of sulfur. It is a brown-yellow unctuous substance used as an application for skin diseases. Thiocol. (Potassium Guaiacol-Sul- fonate.) (98) This is prepared by heating guaiacol with concentrated sulfuric acid to a temperature not exceeding 8o° C, con- verting the guaiacol-sulfonic acid pro- duced into the barium salt, and this into the potassium salt. It is a colorless, crystalline powder, odorless, and having a faint bitter, followed by a sweet taste. It is soluble in about 8 parts of water, slightly soluble in alcohol, and insol- uble in absolute alcohol, ether, or oils. It is said to be non-irritating to the mu- cous membrate of the stomach, therefore being well borne, and to be readily ab- sorbed and assimilated, and is therefore preferred to creosote or guaiacol. It is recommended in pulmonary tuberculosis, acute and chronic bronchitis, whooping cough, etc., as a means of relieving expectoration and diminishing night- sweats. The dose is 5 to 20 grains 3 times a day. It is put up in 5-grain tab- lets or the powder may be dispensed in solution in orange syrup. Thiocol Syrup. See Sirolin. Thiodine Suppositories. (159) These are elastic vaginal suppositories stated to contain 10% of theodine which latter is described as being a combina- tion of ichthyol, iodin, boroglyceride, hjdrastine, carbolic acid, and glycerin. PROPRIETARY AND SYNTHETIC REMEDIES. 861 Thioform. (Basic Bismuth Dithiosa- licylate.) This is a voluminous, insoluble, yel- lowish, odorless powder, insoluble in or- dinary solvents, and containing 72% of bismuth oxid. It is recommended as a non-poisonous substitute for iodoform. When used internally the dose is 5 grains 3 times a day. Thiol. This occurs either as a brownish- black, thick liquid, or as a brownish- black powder, which is soluble in water and alcohol. It is used in the treat- ment of skin diseases, being recom- mended as a substitute for ichthyol. It is used in the form of ointment which contains 10 to 50%. The dry thiol, which is about 2Y2 times the strength of the liquid, is mixed with starch and is used as a dusting powder. Thiolan. This is described as a mild sulfur ointment in which the sulfur is contained partly in a state of solution and partly in suspension. It is said to have proved effective in the treatment of some skin diseases. Thioresorcin. This is obtained by heating resorcin with sulfur. It is a yellowish-gray pow- der of a penetrating odor, insoluble in water, slightly soluble in alcohol and ether. It is an antiseptic which is used externally as a surgical dressing, either as a dusting powder or as an oint- ment. Thiosinamine. (Allylsulfocarba- mide — Allylthiourea — Rhodal- line.) (178) This is in colorless crystals of a slightly onion-like odor, very soluble in alcohol, water and ether, but water decomposes it. It is used by hypodermic injection for lupus and uterine affections in doses of 3 minims in 15% alcoholic or 10% glycerinated solutions 2 or 3 times a week, the dose being gradually increased. It is also used in phthisis and other tubercular diseases in doses of 1 to 3 grains. Thomas' Eye Water. Zinc sulfate gr. 20 Sodium chlorid gr. 20 Rose water fl.oz. 1 — Parrish. Three Chlorides(Henry.) See Henry's Three Chlorides. Thymacetin. This is a thymol derivative analogous to phenetidin. It is a white, crystalline powder, only slightly soluble in water, more soluble in alcohol and ether. It is used as a hypnotic and analgesic in headache, neuralgia, paralysis, insomnia, etc., in doses of 5 to 15 grains. Thymenthol. (181) This is an antiseptic which is stated to contain thymol, menthol, eucalyptol, methyl salicylate, boric and benzoic acids, and baptisia tinctoria. Thymenthol Tablets. These are stated to contain thymol, menthol, eucalyptol, oil of wintergreen, sodium benzoate, borate and bicarbonate. Thymidol. (Hesse & Goldstaub, Hamburg, Mfrs.) This is described as methylpropyl- phenol menthol made of thymol and menthol. It is used in antiseptic mouth washes and tooth pastes. Thyminic Acid. See Solurol. Thymiodide. (211) This is stated to be a combination of thymol iodid, bismuth subiodid and boric acid. It is an orange-colored, odorless powder which is recommended as an antiseptic surgical dressing. Thymol Trichloracetate. This is a compound of thymol and trichloracetic acid. It is in colorless crystals or granular powder, insoluble in water, soluble in alcohol and ether. It is used as an antiseptic dressing for ulcers and wounds. 862 THE STANDARD FORMULARY Thymoloform. (Thymoform.) This is a condensation product of formaldehyde and thymol which forms a yellowish, tasteless powder, proposed as a substitute for iodoform. Thymolyptol. This is described as being a combina- tion of V/z grains of encalyptol, 2 grains each of resorcin, menthol, thymol, and benzoic acid, and 25 grains of "boro- salicyl. acid." Thymoseptic. (133) This is described as containing the essential antiseptic and germicidal con- stituents of thyme, hamamelis virginica, eucalyptus, gaultheria, mentha arvensis, and baptisia, with 2 grains of "benzo- boracic acid" to each fluidram. Thymotal. (Thymol Carbonate.) This is a white powder of a faint odor of thymol, insoluble in water but solu- ble in alcohol, ether and chloroform. It is given internally to destroy tape worms, pin worms, etc., the dose for children being 8 to 15 grains, for adults 30 grains, 3 times daily. It is not de- composed into its constituents until it reaches the intestines. Thymoxol. This is a 1% alcoholic solution of thymol containing 3% of hydrogen per- oxid. It is used in 5 or 10% dilutions as an antiseptic and bactericide. Thyptol. (Liquor Eucalyptus Comp.) (221) This is stated to represent the puri- fied active principles of eucalyptus, men- tha arvensis, thyme, gaultheria, and bap- tisia tinctoria with 12 grains of "benzo- boric acid" to the fluidounce. Thyraden. (109) This is described as a dried extract of sheep's thyroids and therefore con- tains all the constituents of the gland. It is a brownish, nearly odorless powder used in myxcedema, obesity, goitre, rick- ets, etc., in doses of 15 to 30 grains daily. Thyreoidectin. (159) This is a reddish-brown powder pre- pared from the blood of sheep, goats or horses, chiefly sheep, from whom the thyroid glands have been removed. It is used as a remedy for exophthalmic goitre in doses of 5 to 10 grains 3 times a day. It is put up only in 5-grain cap- sules. Thyroiodin. See Iodothyrine. Thyroidinase. This is described as a soluble ferment from the thyroid gland. It is a fine, white powder, soluble in water or gly- cerin, not in alcohol. Thyro-Iodose. See Nigridine. Tinct. Passirlora. See Daniel's Conct. Tinct. Passirlora. Tissue Food. (138) This is stated to be a combination of olive oil, port wine, iodin, phosphorus, and hypophosphites of lime and soda. Tittmann's Purgative Pills. Aloes gr. 90 Jalap root gr. 135 Soap gr. 45 Anise gr. 24 Alcohol to make a mass. Make 100 pills.— D. Tobias' Derby Condition Powder. Tartar emetic av.oz. I Sulfur av.oz. 5 Potassium nitrate av.oz. 5 Black antimony av.oz. 10 Juniper berries av.oz. 10 Fenugreek av.oz. 20 — (Schaedler's Analysis) in Hager. Tobias' Venetian Liniment. Ammonia water parts 5 Camphor parts 2 Tincture of capsicum parts 10 Alcohol parts 20 Water parts 10 — Hager. Tobias' Venetian Horse Liniment. Ammonia water parts 30 Camphor . parts 12 Tincture of capsicum gr. 30 Alcohol parts 200 Water '. parts 60 (Schaedler's Analysis) in Hager. PROPRIETARY AND SYNTHETIC REMEDIES. 863 Toluene. (Toluol.) This is derived from coal tar. It is a colorless, refractive liquid, of a pecu- liar odor. It is only slightly soluble in water, very soluble in alcohol, ether or chloroform. It is used in the man- ufacture of dyes and artificial musk, also as a solvent, and is used as an ingredi- ent of Loeffler's solution for application to diphtheritic membranes. Tolypyrine. (Tolyantipyrine.) This is in colorless crystals which are soluble in 10 parts of water, readily sol- uble in alcohol. It is recommended as an antipyretic, antirheumatic and anti- neuralgic, in doses of 10 to 30 grains. Tolysal. (Tolypyrine Salicylate.) This occurs in colorless crystals, al- most insoluble in water, readily soluble in alcohol. It is employed in acute and chronic rheumatism and rheumatic neu- ralgia, in doses of 15 to 30 grains. Tongaline. (Liquor Tongse Salicy- latus.) Each fluidram is stated to represent Tonga .._ . .gr. 30 Ext. cimicifuga racemosa. . . .gr. 2 Sodium salicylate gr. 10 "Pilocarpin salicylate" gr. 1/100 "Colchicin salicylate" gr. 1/500 Tongaline Tablets. Each 6-grain tablet is stated to con- tain 1 grain of "concentration of fluid tonga," 5 grains of sodium salicylate, yi grain of "cimicifugin salicylate," 1/200 grain of "pilocarpin salicylate" and 1/100 grain of "colchicin salicylate." Tonic Aphrodisiac Tablets. These are stated to contain phos- phorus, ext. nux vomica, damiana, saw palmetto, and ext. coca. Tonic Beef. (182a) This is described by the manufacturers as containing "the nutritive constituents of beef wheat, and fresh eggs in a sol- uble, predigested and hence readily ab- sorbable form." Tonic Hypophosphites. (182a) Each fluidounce is stated to contain l l A grain each of potassium and iron hypophosphites, 1 grain of manganese hypophosphite, l / 2 grain of quinine hypo- phosphite and 1/16 grain of strychnine hypophosphite. Tonic Phosphate. Each teaspoonful is stated to contain 2 grains of iron pyrophosphate, Yz grain of extract of nux vomica, 1/100 grain of phosphorus, and aromatics, q. s. Tono Nervine Tablets. (212) Each one is stated to contain ferri carb., gr. 1, ext. damiana, gr. 1, ext. sumbul, gr. H, asafetida, gr. x / 2 , phos- phorus, gr. 1/100. Tono Sumbul. (212) This is stated to contain sumbul, iron, calisaya, phosphoric acid, sherry wine and aromatics. Tonols. (178) This is the name given to identify this particular brand of glycerophosphates. Toril. This is described as a solid, soluble extract of meat, including all the albu- minoids. Traumaticin. What is sold under this name is a solution of gutta percha in chloroform. It is a brownish colored liquid which is used like collodion and for the same purpose, a covering and protective for wounds. Traumatol. See Cresol Iodid. Triacol. (Elixir Guaiacol Co.) Each dessertspoonful is stated to con- tain Potassacol gr. 2 x / 2 Sodacol gr. 2^/2 Terpin hydrate gr. 2 Morphacol gr. Y% Benzoin and aromatics, q. s. Sugar of glucose none Potassacol, sodacol and morphacol are the potassium, sodium and ethylmor- phine salts of guaiacol-sulfonic acid. Triberane. This is a French purgative mixture said to contain alcoholic extract of sen- na, glycyrrhiza 20, sugar 20 precipi- tated sulfur 10, and vanillin, to flavor. 864 THE STANDARD FORMULARY Trichloracetic Acid. This is a deliquescent crystal, melting at 52 C, and is very soluble in water, alcohol and ether. It is used as an escharotic for destroying warts, nsevi, corns, etc., as an astringent for gonor- rhea, indolent ulcers, etc., and as a test for albumin in urine. Trichophytin. This is a liquid filtrate obtained from cultures of trichophyta, the fungi which destroy the hair cells. This liquid has been sterilized and then preserved with J4% of phenol. It is used for some diseases of the hair and scalp. Tri-Ferment Comp. The powder is stated to contain pure pepsin, pancreatin, diastase, lactic acid, and hydrochloric acid. It is also put up in the form of 5-grain tablets and elixir. Triferrin. (Iron Paranucleinate.) (109) This is prepared by digesting cow's milk casein with pepsin and precipitating the solution with a ferric salt. It is a tasteless powder, soluble in a weak solution of sodium hydroxid, but insol- uble in weak hydrochloric acid. It con- tains 22% of iron, 9% of nitrogen, and 2}/ 2 °/c of phosphorus in natural (or- ganic) combination. In addition to its hematinic action derived from iron, it is also claimed to act like lecithin on account of the phosphorus in organic combination it contains. It is said to agree with the most sensitive stomach since it passes the stomach unchanged but is freely absorbed in the intestines. It is recommended in anemia, chlorsis, neurasthenia, general debility, etc. The dose is 5 grains 3 times per day. Trifcrrol. (109) This is an elixir of triferrin said to contain 1 grain of triferrin in 1 fluid- dram. The triferrin is dissolved in a vehicle consisting of water, alcohol, tincture of orange, compound tincture of cardamon and vanillin. It contains 15% of alcohol. It was introduced as a convenient substitute for triferrin. The dose is a tablespoonful 3 times a day. Trigemin. This is a compound resulting from the action of butylchloral upon pyramidon. It is in long, colorless needles which are freely soluble in water, yielding a solu- tion of a faintly aromatic odor and taste. It turns yellowish or brownish on exposure and then is no longer fit for use. It is used for various headaches and neuralgias in doses of 8 to 15 grains 3 times daily. Trikresol. (178) This is a liquid said to consist of 35% of orthocresol, 40% of metacresol, and 25% of paracresol. It is therefore simi- lar to cresol, U. S. P. It is readily solu- ble in alcohol, ether or fixed oils, only soluble to the extent of 2% in water, but stronger than ^2 to 1% solutions are never required. It is used as an antisep- tic like phenol but is much stronger. The internal dose is 1 or 2 minims 3 times a day. Trikresolamine. See Kresamine. Trinitrin. This is a synonym for nitroglycerin. Trional. (Diethylsulfonethylmethyl* methane — Sulphonethylmethane, U. S. P.) This is in colorless, lustrous scales, odorless and of a bitterish taste. It is soluble in 195 parts of water at 25 C, more readily soluble in boiling water, alcohol or ether. It is prescribed as a hypnotic and nerve sedative in 1 5-grain doses, which are best given in hot drinks. Triosine. This is described as a combination of the desirable principles of triticum and pelosine with saline and herbal diuretics. It is recommended for nephritis. Triotonol. (178) Tablets containing 2^2 grains each of calcium and sodium glycerophosphate and 1/60 grain of strychnine glycero- phosphate. The dose is 1 or 2 tablets 3 times a day. PROPRIETARY AND SYNTHETIC REMEDIES. 865 Tripartol. (76) This is described as a white, fluid product of petroleum combined with benzoin, phenol, thymol, menthol and eucalyptol. Trioxymethylene. See Paraform. Triphenin. (130) This differs from phenacetin in that acetic acid has been replaced by pro- pionic acid. It is a white, shining, cry- stalline, odorless, faintly bitter powder. It requires about 2000 parts of water for solution, but is freely soluble in alcohol or ether. It is recommended as an anti- pyretic in typhoid fever, pneumonia, pleurisy, influenza, etc., in doses of 4 to 10 grains 3 or 4 times daily, as an anal- gesic in neuralgia, sciatica, migraine, etc., in doses of 15 or 20 grains. Tritica. (181) This is described as a concentrated in- fusion of the rhizome of triticum. Tritipalm. (187) This is a preparation each teaspoonful of which is stated to represent 30 grains of fresh saw palmetto and 60 grains of triticum repens. Tritols. (Oil Triturates.) These are preparations patented in Germany which consist of emulsions of various drugs with extract of malt. Among some of the combinations are cod liver and castor oils and oleoresin of male fern. Tropacocaine Hydrochlorid. (Ben- zolypseudotropeine Hydro- chlorid.) This is an alkaloidal salt from the Java coca plant, but is also prepared synthetically from tropinon or tropine by electrolytic reduction. It is readily sol- uble in water. It is used as a substitute for cocaine ; it is said to be less toxic, less depressing on the heart, more prompt, and to yield more stable solutions. It is used in 3 to 10% solutions, preferably in a 0.6% solu- tion of sodium chlorid. Trophonine. (167) This is stated to contain egg-albumen, beef and wheat, partially. digested, with which are combined the enzymes of all the digestive organs, and nuclein from the lymphoid glands. It is described as a saturated solution of nucleoalbumins and nucleoproteids and also containing nucleo-enzymes. Tropon. This is an imported nutritive which is stated to contain 90% pure albumen. Trousseau's Arsenical Cigarettes. One part of sodium arsenate is dis- solved in 50 parts of water and bibulous paper is saturated with this solution, rolled into cigarettes, and allowed to dry. Each cigarette should contain 5 centigrams of sodium arsenate. Trousseau's Diuretic Wine. Digitalis gr. 90 Potassium acetate gr. 135 Juniper berries av.oz. 1 White wine fl.oz. 16 Reduce the digitalis and juniper to coarse powder, macerate in the wine for 4 days, strain, and in the liquid dissolve the salt. — Bouchardat's Formulaire. Trygase. (172) This is stated to be a chemically pure yeast, forming a light gray powder, in- soluble in water, and having the odor and taste of yeast. It is intended for use like other yeast preparations. Trypsin. (14) This is the proteolytic ferment of the pancreas and is prepared from the fresh pancreas of hogs. It is a light yellow powder, possessing a faint odor and a meat-like taste. It is not completely sol- uble in water at once but dissolves al- most entirely in time. It is insoluble in alcohol or ether. It is decomposed at temperatures above 105 F. It lias the power of digesting proteid materials ; it acts best at 104 F. and in a slightly alkaline medium. When applied locally in solutions made alkaline with sodium carbonate it dissolves diphtheritic and other false membranes. It is claimed to 866 THE STANDARD FORMULARY have the power of destroying the cells of cancer without acting on the healthy tissue. It is applied locally by means of a brush or spray. About 6 grains are to be mixed with 2 grains of sodium bicar- bonate and triturated in a mortar while adding 1 or 2 drams of distilled water, then warmed to 38 to 40 C. and applied immediately. The application may be re- peated several times an hour if neces- sary, a fresh solution being made before each application. The internal dose is 2 grains or more 3 times a day. Trypsin Glycerole. This is a 70% glycerin solution con- taining approximately 5% of trypsin powder. It is a yellowish or brownish clear liquid of sweetish taste and pecu- liar characteristic odor. It should be kept in a cool place. It is intended for internal and hypodermic use in the treat- ment of cancer. The dose internally is 1 to 2 fluidrams 3 times a day; hypo- dermically, 5 minims every other day, gradually increased. Trypsogen. These are tablets stated to contain the enzymes of the islands of Langerhans with the tryptic and amylolytic ferments of the pancreas, 1/100 grain of gold bromid and 1/200 grain of arsenic bro- mid. They are of a light brown color, a faint odor and a sweetish taste. It is claimed to be of special value in diabetes and glycosuria, also said to be of value in anemia, chlorosis, chorea and neuras- thenia. Tuberculin. (Paratoloid.) This is a sterilized glycerin extract of pure cultures of the tubercle bacillus as introduced by Dr. Robert Koch. It is a transparent, light-brown liquid which is now mainly employed as a diagnostic agent against suspected tuberculosis, Koch himself having abandoned its use for curing the disease. It is injected un- der the skin, a few minims at a time, and observing if the injection is fol- lowed or not by specific and characteris- tic symptoms. It is now used mainly to detect tuberculous taint in cattle. Tuberculocidin. This is a pulverulent substance de- rived by Prof. Klebs from Koch's tuber- culin by eliminating certain toxic bodies and leaving in solution an albumose, which thereupon is precipitated by alco- hol. It is believed to represent the bene ficial properties of crude tuberculin. It is much less dangerous than Koch's lymph. Klebs having administered as much as 1 cc. to tuberculous patients. The dose hypodermically 1/20 to 1/10 grain to begin with, rising rapidly. Tuklin. This is stated to be an acidified mix- ture of formalin, alcohol and ether, flav- ored with aromatic essential oils. It is intended for use as an antiseptic inhal- ant in treatment of diseases of the air passages. Tulase. This is a preparation made by Behring which is stated to contain all the con- stituents of Koch's bacillus. It is rec- ommended as a cure for tuberculosis. Tumenol Paste. (Tumenol Venale.) This is a crude mixture of variable proportions of tumenol sulfone and tu- menol sulfonic acid derived from bitu- minous shale. It is a dark, reddish- brown oil of syrupy consistence, almost insoluble in water but easily soluble in fats, ether or benzol. It is recommended in eczema, superficial ulcerations, excori- ations, burns, etc., as a palliative and protective covering. It is used in 5 to 20% ointment or a 10% mixture with water or glycerin. Tumenol- Ammonium. This is the ammonium salt of tume- nol-sulfonic acid. It is a dark, oily sub- stance of a faint tarry odor and acrid taste. It is soluble in water in all pro- portions, also soluble in alcohol, ether or glycerin. It is applied as a local dress- ing in the form of a 5 to 10% aqueous PROPRIETARY AND SYNTHETIC REMEDIES. 867 solution, a 5 to 10% tincture containing equal parts of ether, alcohol and water or glycerin, or a 5 to 20% ointment. Tumenol Oil. (Tumenol Sulfone.) This is a mixture of the sulfonated constituents of tumenol venale which are non-combinable with alkali. It is a dark, t&ick, oily liquid, but easily soluble in ether. It is used for the same purposes as the preceding. Tumenol Powder. (Tumenol-Sulfonic Acid.) This consists of the sulfonated con- stituents of tumenol venale, capable of combining with caustic alkalies. It is a dark-colored powder, sparingly soluble in cold water but readily soluble in hot water and in dilute ammonia water. It is used for skin diseases as are the other tumenol preparations. It is used in sub- stance, finely powdered, or as a 5 to 10% paste with or without zinc oxid. Turck's Compound Emulsion. This is stated to be made with predi- gested cod liver and fruit oils. Turicin. This is stated to be a compound of tannin and gluten. It is a fine, tasteless, inodorous, flesh-colored powder, insolu- ble in water but soluble in dilute alka- lies, and containing 21% of tannin. It is used in the diarrheas of adults. When taken internally it is not decomposed un- til it reaches the intestines. The dose is 10 to 30 grains. Tussiculin. This is a cough remedy stated to be prepared from 3^ g. each of the vola- tile oils of melaleuca leucodendron, ser- pyllum, persica vulg. and 45 g. of tinc- ture of alkanet. — Phar. Centralh. Tussol. (Antipyrin Mandelate.) This is a white, crystalline, bitter pow- der. It is soluble in 15 parts of water, 3 or 4 parts of alcohol and 25 of ether. It is decomposed by milk, milk food and alkalies. It has been extolled for the treatment of whooping cough. The dose is "fa to 8 grains according to age. 5* Tutulin. This is a vegetable albumin. It is a fine yellowish-white powder, without odor or taste, and intended as a food in the dietetic treatment of typhoid fever and other cases where it is found diffi- cult to give a nourishing diet. Tyalid. This is described as a combination of ptyalin, pancreatin and malt diastase. It is marketed in the form of powder, tab- lets and elixir. Tyndale's Compound Syrup of Eu- calyptus. This is stated to contain Eucalyptus globulus, Eucalyptus resinifera, hore- hound herb, elecampane root, licorice root, and comfrey root. There are two forms, Nos. 1 and 2, the former con- taining 2 grains of ammonium chlorid to the fluidram, the latter 1/32 grain of morphine acetate to the fluidram. Tyree's Antiseptic Powder. Formula as published by the manu- facturer, in parts: Sodium borate, 50; alum, 50 ; carbolic acid, 5 ; glycerin, 5 ; the crystallized principles of thyme, 5, eucalyptus, 5, gaultheria, 5, mentha, 5. Tyree's Buchu and Hyoscyamus Comp. Each dessertspoonful is stated to con- tain 10 grains of buchu, 5 grains each of uva ursi, pareira, hyoscyamus and hops, 10 grains of potassium acetate and 15 drops of "aetherial ( !) spirits of nitre." Tyree's Hypophosphite Powder Comp. See Hypophosphite Powder Comp. trimarine. This is a mixture of salicylic acid esters of aliphatic alcohol containing 75% of salicylic acid. It is a reddish- brown, neutral or slightly acid fluid, with a weak pleasant odor and burning taste. It is insoluble in water but solu- ble in 2 parts of alcohol. It has boon used in articular rheumatism and similar affections, applied like methyl salicylate in the form of applications with a brush. followed by packing with cotton. 868 THE STANDARD FORMULARY Ulyptol. See Eulyptol. Unada. This is an effervescent laxative tablet which is stated to contain magnesium sulfate, sodium phosphate, sodium bicar- bonate, lithium carbonate, and quinine bisulfate. Unger's Cure for Drunkenness. Dr. Unger's cure for drunkenness was loudly vaunted about 20 years ago, but its uselessness was subsequently proved. As it is still occasionally asked for, it is here given : Take 1 pound of best, fresh, quill red Peruvian bark, powder it, and soak it in 1 pint of diluted alcohol. Afterward strain and evaporate it down to half a pint. Dose : A teaspoonful every 3 hours the first and second day, and oc- casionally moisten the tongue between the doses. It acts like quinine, and the patient can tell by a headache if he is getting too much. The third day take as previous, but reduce the dose to Yz tea- spoonful. Afterward reduce the dose to 15 drops, and then down to 10, and then down to five drops. To make a cure, it takes from 5 to 15 days, and extreme cases 30 days. Seven days are about the average in which a cure was said to be effected. — Pharm. Ungrol. This is a glycerogelatn preparation medicated with sublamin, intended for the treatment of gonorrhea and syphilis. It is supplied in tin tubes, accompanied by a canula for the introduction of the remedy. Unguentine. (148) The formula given is : Carbolic acid, 2% ; ichthyol, $% ; alum, 15 to 16%, the vehicle being petrolatum. The manufac- turers state that "by a process of our own we eliminate most of the astringent properties of the alum, thus rendering it non-irritable in this large amount." It is a fact, however, that the astring- cncy of alum is an inherent property. Unguentine Cones. These are rectal suppositories stated to contain "alum (non-irritating)," ergo- tin, menthol, ichthyol, extracts of opium and belladonna, carbolic acid, and cocoa butter. Unguentine Crayons. These are urethral bougies said to contain corrosive sublimate, 1/200 gr., morphine, 1/12 gr., zinc sulfocarbolate, 1/16 gr., "alum (non-irritating)," l /% gr., powdered golden seal, 1/16 gr., protar- gol, 1/10 gr., and cocoa butter. Unguentine Pencils. These are intra-uterine bougies each said to contain corrosive sublimate, 1/100 gr., zinc sulfocarbolate, y% gr., "alum (non-irritating)," i]/ 2 gr., ichthyol, 2 gr., powdered golden seal, *4 gr., protargol. y 5 gr., and cocoa butter, q. s. Unguentine Pessaries. These are vaginal suppositories which are stated to contain "alum (non-irri- tating)," carbolic acid, ichthyol and a glycerogelatin vehicle. The No. 4 pessaries are stated to con- tain "alum comp. (non-irritating)," 10 gr., ichthyol, 2 gr., phenol, 2 gr., boric acid, 15 gr., aromatic antiseptic ols, and a glycogelatin vehicle. Unguentum Crede. See Collargol Ointment. Ungt Betulse Comp. This is stated to be composed of oil of birch tar (Russian), salicylic acid, and diachylon plaster. Uralium. (Uraline — Chloral-Ure- thane.) This is a white powder, insoluble in cold water, decomposed by hot water, soluble in alcohol and ether. It is used as a hypnotic in doses of 15 to 45 grains, and is supposed to be superior to chloral. Uranium Nitrate. This is in yellow crystals, soluble in water, alcohol, or ether. It is recom- mended for diabetes but does not dimin- ish the elimination of sugar. The dose is 1 or 2 grains 3 times daily, the dose PROPRIETARY AND SYNTHETIC REMEDIES. 869 being gradually increased to 15 grains. Uranium salts, made into plaster, are recommended as application to lupus. Urasol. (116) This is a condensation product of ace- tic and salicylic acids and formaldehyde. It is in very fine crystals which are solu- ble in ether or alcohol but insoluble in water. It is used as a uric acid solvent and for uric acid poisoning, and in the treatment of rheumatism, gout, pneu- monia, influenza, typhoid fever, scarlet fever, etc., in doses of 5 to 8 grains. Urea. (Carbamide.) This is a constituent of urine but is formed artificially by heating ammonium cyanate. It is in white crystals which are soluble in water or alcohol. It is used as a diuretic in renal calculus, also an antitubercular. The dose is 10 to 20 grains in water 3 or 4 times a day. Urethane. (Ethyl Urethane— Ethyl Carbamate.) This is an ester of carbamic acid ob- tained by the action of alcohol on urea. It is in colorless, odorless crystals, hav- ing a saline taste. It is very soluble in water and other solvents, and is decom- posed by acids and alkalies. It is used as a hypnotic but it has no direct anal- gesic influence, and hence has never be- come popular. The dose is 15 to 45 grains. It is recognized by the U. S. P. Urgosan. (172) This is put up in gelatin capsules, each one containing 5 grains of gonosan and 2J/2 grains of hexamethylenetetramine. It is used in the treatment of inflamma- tion of the bladder, following gonorrheal infection of the urinary tract. Uric Solvent, Hayden's. (145) This is stated to represent Althaea officinalis, Epigsea repens, Iris versi- color, Juniperus communis, Polytrichum juniperus, lithium citrate, sodium ace- tate, and potassium nitrate. Uricsol. This is stated to be a concentrated so- lution of lithium citrate and sodium phosphate. Uriform. (179) Each 2 fluidrams is stated to contain Hexamethylenetetramine gr. 7^2 Saw palmetto gr. 5 Santal gr. 2Y2 Damiana gr. 2^ Coca . gr. 2^> Nux vomica gr. *4 In a menstruum containing 20% of alcohol with sugar and aromatics. Uriseptin. (79) This is described as a solution of hex- amethylenetetramine with lithia and con- taining fluid extracts of couch grass and corn silk. The manufacturers state that lithium oxid and formaldehyde are in combination, the mixture representing 26.77 grains per fluidounce. Uritone. (159) This is the same as Hexamethylenete- tramine, which see. Urocitral. (175) This is stated to be chemically theo- bromine sodium citrate, a white powder, readily soluble in warm water, and con- taining 40% of theobromine. It is used as a diuretic in doses 7^ to 15 grains several times a day. Urol. This is the name for quinate of urea. It is in white crystals, readily soluble in water or alcohol. It is used for gout and gravel in doses of 10 to 30 grains. Urocol. These are tablets each containing l / 2 g. of urol, J /2 g. of milk sugar, and 1 mg. of colchicin. These are used to cut short acute attacks of gout, 4 or 5 being generally sufficient. Uroformin. (63) This is stated to be hexamethylenete- tramine. It is marketed in the form of powder and as 5-grain tablets. Uroformin Comp. Elixir. See Elixir Uroformin Comp. Urolysin. This is stated to be a mixture of citro- zon with 10% of quinic acid. See Citro- zon. It is used as a remedy for gout. 870 THE STANDARD FORMULARY Uropherin-B. (Theobromine and Lithium Benzoate.) (130) This is a double salt of theobromine- Hthium and lithium benzoate. It is a white powder containing 50% of theo- bromine, and soluble in 5 parts of water. It is decomposed on exposure to light and air. It is a diuretic recommended for dropsy and diseases of the heart and genitourinary organs. The dose is 5 to 15 grains. TJropherin-S. (Theobromine and Lithium Salicylate.) (130) This is a double salt of theobromine- lithium and lithium salicylate. Proper- ties, uses and dose are the same as those of uropherin-B. Uropurgol. This is another name for Urotropine- New, which see. TJropurin. This is a dry extract of uva ursi leaves which is supplied commercially in the form of compressed tablets, each of which is stated to contain ^4 gr.'of the dried extract. Urosine. (Lithium Quinate.) This is in colorless, odorless "crystals of a saline taste, readily soluble in water, sparingly in alcohol and insoluble in chloroform and ether. It is recommend- ed for gout, stone in the bladder, cystitis, and uric acid diathesis. It is supplied in the form of powder or as effervescent tablets each containing quinic acid, 7^ gr., lithium carbonate, \V 2 gr., and sugar, AV2 gr. Urotropine. This is the same as Hexamethylenete- tramine, which see. Urotropin-New. (TJrotropin Methy- lene Citrate.) See Hexamethylenetetramine methy- lene citrate. The dose is 15 grains 3 times a day. TJrotropin Quinate. See Chinotropin. TJrotropin Tannate. See Tannopine. TJrsin. This is a compound of quinic acid and lithium. See Urosin. TJrystamine. (185) This is stated to be chemically hexa- methylenetetramine lithium-zenzoate. It is soluble in water, and is recommended for gout, rheumatism, vesical and ure- thral catarrh, and as a urinary antiseptic in doses of 15 grains. Ustadine. (177) This is stated to contain the active principle of Ustilago maydis, nux vom- ica, and aromatic extracts. Uterine Tonic Sedative. See Elixir Viburnum and Hydrastis Comp. Uterine Tonic Cordial. (182a) Each fluidounce is stated to contain 60 grains each of black haw and golden seal and 30 grains of Jamaica dogwood. Uterol. This is now known as Utros, which see. Uterotonic Compound. (143) Each fluidounce is stated to contain Squaw vine gr. 40 Black haw gr. 40 Jamaica dogwood gr. 30 Golden seal gr. 20 Black cohosh gr. 20 Cascara sagrada .gr. 10 Henbane gr. 4 Potassium bromid gr. 10 Utonia. (173) This is described as a preparation of mitchella, helonias, senecio, aletris and cimicifuga. Utros. (Elixir Viburnum Comp.) (141) Each fluidounce is stated to represent Cramp bark gr. 30 Hydrastis gr. 30 Black haw gr. 20 Aletris gr. 15 Squaw vine gr. 15 Blue cohosh gr. 15 Cascara sagrada gr. 15 Somnos m. 120 PROPRIETARY AND SYNTHETIC REMEDIES. 871 Vaginal Wafers. (138) Each is stated to contain Salicylic acid gr. I Tannic acid gr. 2 Boric acid . . . gr. 3 Extract of opium gr. x% Extract of helonias gr. l / 2 Extract of henbane gr. I With thymol, eucalyptol and alum. Vaginoids. (141) These are vaginal suppositories, each one of which is stated to contain Phenol gr. 2 Ichthyol . gr. 1^4 Zinc sulfocarbolate gr. 1 Iodin gr. l / 2 Boroglyceride and gelatin, q. s. Vagipos. (84) This is stated to contain menthol, thy- mol, iodin, hydrastis, one of the newer anesthetics, with gelatin and boroglyce- ride. Validol. (222) This is the menthylester of valerianic acid with 30% of free menthol. It is a clear, colorless liquid, of a mild, pleas- ant odor, insoluble in water, readily sol- uble in alcohol, ether, chloroform, and oils, and is decomposed by alkalies. It is an analeptic, antihysteric, carminative and stomachic, and is recommended in hysteria, migraine, gastralgia, gastritis, vomiting of pregnancy, and all reflex neuroses, and is said to be a specific against seasickness. It is said to be well borne by the most sensitive stomach. The dose is 10 to 15 drops on a little sugar or in a little sweet wine, 3 times a day. Validol, Camphorated. This is validol with 10% of camphor dissolved in it. It is recommended in serious cases of exhaustion, where the administration of camphor is indicated; in odontalgia, either by application to the pulp or inserted on cotton into the pre- viously cleansed cavity. The dose is 10 to 15 drops. Valofen. (96) This is a patented liquid preparation intended to replace recently prepared in- fusions of valerian. It is stated to con- tain ethyl valerate, ammonium valerate, and the active constituents of pepper- mint. The dose is 10 to 25 drops. Valyl. This is the diethylamid of valerianic acid. It is a colorless, neutral liquid, of a pepper-like odor and a burning taste. It is soluble in 25 parts of water and is easily soluble in alcohol or ether. It should not be exposed to the air. It acts as a sedative, antispasmodic and nervine, similar to valerian, and is recommended in hysteria, hemicrania, neuralgia, in- somnia due to nervousness, etc. Owing to its liability to oxidize when exposed to the air, it is supplied only in the form of gelatin capsules, each containing 2 grains, the dose being 2 or 3 capsules, best given during or immediately after meals. Van's Mexican Hair Restorative. The composition of this is given thus by the manufacturers : Glycerin, cactus, salt, vinegar, extracts from several Mex- ican roots and flowers, alcohol and per- fume. According to a testimonial from Dr. F. L. James, he qualitatively analyzed the mixture and found neither lead nor other harmful mineral. Vanier's Iodized Syrup Quinine. This is stated to have this' composi- tion : Potassium iodid .-. g. 3 Fluid ext. cinchona g. 25 Fl. ext. of bitter orange peel. .g. 5 Fluid extract of walnut g. 50 Alcohol, 30% g- 17 Simple syrup g. 900 Varalettes. (25) These are effervescent salts put up in the form of compressed tablets. Various substances are put up in this form, such as antipyrine, antipyrine and caffeine, so- dium bromid, lithium citrate, caffeine, etc. Vaseline Emulsion. (39) This is stated to be a combination of vaseline, glycerin, hypophosphites of lime and soda, and certain food prod- ucts. 81 THE STANDARD FORMULARY Vasenol. This is an ointment vehicle prepared by mixing petrolatum and fatty alcohols derived from wax, spermaceti and lano- lin. It is said to have the property of taking up considerable water. It is put up as a soft ointment, a powder and a liquid. Vasogen. (161) This is described as an oxygenated hydrocarbon which has the power of rendering many other substances mixed with it soluble in or emulsifiable by wa- ter. It is put up in various combina- tions, such as iodin, 6 and io%, guaia- col, sulfur, tar, mercury, menthol, iodo- form, etc., all of which are to be applied externally. Vasopolentum. (175) This is the name applied to an olein- paraffin mixture which in the solid form is intended as an ointment vehicle and in the liquid form as a solvent for iodin and other substances intended for exter- nal application. Vera Diastase. (187) This is a diastasic ferment obtained from the pancreatic gland of the pig. It is a light yellowish-white powder, having a faint odor and a somewhat mucilagin- ous taste. It is not entirely soluble in water but the diastasic principle is, how- ever, completely soluble so that its solu- tions may be filtered without loss of ac- tivity. It is incompatible with strong alcohol, alkalies, acids, and other sub- stances incompatible with ferments. It is claimed to digest 150 times its weight of starch in 10 minutes, under proper conditions. It is recommended as a di- gestant of starchy food in amylaceous dyspepsia in doses of 2 grains or more. It is marketed in the form of powder, 2-grain tablets, and as essence, which see. Vera Diastase Essence. This is a liquid containing 2 grains of vera diastase to each fluidounce, in a menstruum containing 14% of alcohol, 12^2% of glycerin, and flavoring mat- ters. The dose is a tcaspoonful. Veracolate. This is a combination of bile acids with extract of cascara, which is mar- keted in tablet form. Veratrol. This is the dimethylether of pyroca- techin. It is a clear liquid, insoluble in water but soluble in ether, alcohol and fixed oils. It is used externally as an application in intercostal neuralgia and internally against pulmonary tuberculosis instead of guaiacol. The dose is 2 drops 3 times a day. Veratrone. (159) This is described as a non-alcoholic, physiologically standardized preparation of veratrum viride of one-fourth the strength of the fluid extract. It is suit- able either for internal or hypodermic administration. The dose is 15 to 30 minims orally or 10 to 15 minims hypo- dermatically. Vermifugin. (85) This is stated to be composed of jalap, santonin, scammony resin, calomel and sugar. Vereform Antiseptic. (203) This is a yellowish liquid described as a solution of soap containing 6% of for- maldehyde gas. It is practically neutral, is miscible with water in all proportions, and is incompatible with alkaline earths, heavy metals and acids. It is approxi- mately one-sixth the strength of the U. S. P. solution of formaldehyde. A solu- tion containing 1.6% is said to be equal in antiseptic value to a 1 in 1000 solution of mercuric chlorid. A solution contain- ing 1% or over is used for sterilization of the hands and of the field of opera- tion. Veroform Germicide. This is a yellowish liquid described as a solution of soap containing 20% of formaldehyde. It has properties, etc., similar to veroform antiseptic, which see. It is used as a bactericide and de- tergent. It is approximately one-half the strength of the U. S. P. solution of formaldehyde. PROPRIETARY AND SYNTHETIC REMEDIES. 873 Veronal. (Diethylbarbituric Acid — Diethylmalonylurea.) This is a white, crystalline powder, odorless, of a faintly bitter taste, solu- ble in about 150 parts of cold water and 12 parts of boiling water. It forms al- kaline salts which are easily soluble. It is recommended in simple insomnia, as well as in that accompanying hysteria, neurasthenuia, and mental disturbances. The dose is 5 to 15 grains in hot water, tea or milk, or in wafer or capsule fol- lowed by a cupful of a warm drink. Vesipyrin. This is acetylsalol, being to salol what aspirin is to salicylic acid. It is in white crystals, insoluble in water but soluble in alcohol and other similar solvents. It is recommended for acute articular rheumatism in doses of 15 grains. Vestosol. This is stated to be an ointment con- taining 2% of formaldehyde with some zinc oxid and boric acid. It is recom- mended especially for bromidrosis and hyperidrosis. Vial's Capsules of Oil of Juniper. These are stated to contain, accord- ing to Hager, a mixture of oil of juni- per berries and empyreumatic oil of juniper. Viburnal. (205) Each fluidram is stated to represent 10 grains each of Viburnum prun. and Cimicifuga racemosa and 20 grains of "Helonias comp." The menstruum is stated to be wine. Vibutero. (187) This is an elixir, each fluidounce of which is said to represent 40 grains of black haw, 30 grains of cramp bark, 20 grains each of squaw vine, wild yam, Jamaica dogwood, and saw palmetto ber- ries, and 5 grains of Pulsatilla, in a menstruum containing 17% of alcohol. Viferral. See Hydronal. Villosa Compound. (49) This is stated to contain 30 grains each of Dioscorea villosa and Viburnum oxycoccus, 15 grains each of Scutel- laria .lateriflora, Hydrastis canadensis, and Cinnamomum zeylanicum, 20 grains of chloral hydrate, and 4*0 grains of potassium bromid to each fluidounce, with suitable aromatics. Vin Nourry Iodotane. See Nourry's Iodinated Wine. Vindone. A trade synonym for grape juice. Vinette. (193) Each two fluidounces is stated to con- tain 4 grains of iron hypophosphate, 10 grains each of potassium and sodium hypophosphites, 15 grains of magnesium hypophosphite, T / 2 dram of tincture of sweet orange, 1 dram each of the com- pound tinctures of gentian and cin- chona, and sherry wine and carmina- tives. Vinopyrin. This is a tartaric acid combination of paraphenetidin and is therefore closely related to phenacetine. It is a white crystalline powder, soluble in 25 parts of cold water, more soluble in boiling water with some decomposition, less readily soluble in alcohol, and insoluble in ether. It is used as an antipyretic and antineuralgic in doses of 10 to 15 grains three or four times a day. Vioform. (Iodochloroxyquinolin.) This is a very voluminous greenish- yellow powder, nearly odorless, insolu- ble in water, slightly soluble in alcohol, and is six times as bulky as odoform. It contains about 42% of iodin. It is used as an antiseptic and hemostatic and is said to be non-toxic and non-irritant. It is used as a dusting powder, and in ointments, sprays, suppositories or gauze (which see). Vioform Gauze. This is gauze impregnated with a so- lution of 10 g. of vioform, 50 g. of abso- lute alcohol, 10 g. of sugar, 25 g. of glycerin, and 500 g. of water. Viola Cream. According to Campbell's analysis this contains 2.8% of corrosive sublimate. 874 THE STANDARD FORMULARY Virilin. This is stated to be a combination of yohimbin, zinc phosphid, and glycero- phosphates of lime, soda, iron, and strychnine. It is put up in boxes contain- ing 21 capsules. It is recommended as an aphrodisiac. Virol. (27) This is stated to be composed of ex- tract of malt, red bone marrow, and fresh eggs. Viscin. This is a glutinous substance resem- bling bird lime and is employed as a substitute for rubber in the manufacture of such articles as adhesive plaster and as a means of applying remedies in skin diseases. Its advantage over rubber is its price. Viscolan. This is a mixture of 3 parts of puri- fied viscin (which see) and 2 parts of anhydrous wool fat. It is a neutral ointment vehicle which does not become rancid. Viskolein. (123) This is put up in three forms, the for- mulas for which according to the manu- facturers are as follows : No. 1 (6-grain tablets). — Phenylamine, caffein, "kolein" and boric acid, in chem- ical proportions, 5 17-20 grains; menthol, thymol and eucalyptol, each 1/20 grain. No. 2 (6-grain capsules). — Sulfocar- bolates of zinc and soda, each 2 grains, "kolein," i l / 2 grains "phenol-benzolate," 7/20 grain, menthol, thymol and eucalyp- tol, each, 1/20 grain. No. 3 (Hypodermic solution). — This is a saturated solution of No. 2. Vitalic Hypophosphites. (143) This is stated to contain the following hypophosphites in each fluidounce : Po- tassium, l]/ 2 grains, sodium, i]/ 2 grains, iron, 1% grains, manganese, 1 grain, quinine, 7/16 grain, and strychnine, % grain. Vitose. (191) This is a new ointment vehicle which fs described as a glycerin-oil-albuminate. It is said to be odorless, without tend- ency to rancidity, and miscible with glycerin, water or oils. Volesan. This is put up in gelatin capsules each one of which contains approximately 1/24 grain of heroin, 4 grains of tolu balsam, 1 grain of camphor, and 5 grains of creosote carbonate. Voseptol. This is a vanadium preparation which has been recommended as a useful anti- septic and healing application to wounds and abraded surfaces. Vulneral. This is said to contain benzoin, myrrh, petrolatum, spermaceti, lanolin, boric acid, zinc oxid, carbolic acid, aluminium acetate, camphor and lard. Vulnoplast. This is an antiseptic gauze dressing composed of three layers, the lower one being covered with a gelatin vehicle con- taining 10% of protargol and 5% of xeroform. The second layer is absorb- ent cotton and the third layer is medi- cated gauze again. "W-A" Intestinal Antiseptic. This is stated to be a mixture of the chemically pure sulfocarbolates of lime, soda and zinc. Wampole's Antiseptic Solution. See Formolid. Wampole's Preparation of Cascara Bark. Each fluidram is stated to represent 15 grains of cascara sagrada, 7 l A grains each of mandrake and dandelion, and aromatics. Wampole's Preparation of Extract of Cod Liver. This is stated to contain a solution of the extractive obtainable from fresh cod liver, combined with liquid extract of malt, fluid extract of wild cherry bark, and compound syrup of hypophosphites (containing calcium, sodium, potassium, iron, manganese, quinine, and strych- nine). PROPRIETARY AND SYNTHETIC REMEDIES. 875 Ward's Essence for Headache. The following resembles and is gen- erally sold for it (Cooley) : Camphor av. oz. 3 Oil of lavender fl. dr. 4^ Ammonia water fl. oz. 8 Alcohol fl. oz. 20 Mix, close the vessel, and agitate oc- casionally until the camphor is dis- solved. Waterbury's Cod Liver Oil (Meta- bolized) Compound. (214) This is stated to contain "Cod liver oil (metalbolized)".25% Unfermented malt extract 25% Hypophosphites co. special 25% Extracts cherry, eucalyptus and armatics 25% It is also put up so that each table- spoonful contains 2 minims of creosote and 1 minim of guaiacol. Waterbury's Glyco-Chlorides. See Glyco-Chlorides. Watt's Anti-Rheumatic Pills. Aloes gr. 240 Gamboge gr. 240 Hellebore gr. 120 Calomel gr. 30 Guaiac gr! 30 Yellow sulfid of antimony, .gr. 15 Oil of clove m. 30 Soap gr. 60 Spirit of camphor sufficient Make into 5-grain pills. — Nat. Dr. Waterhouse Uterine Wafers. The formula given in the advertise- ments is "ex. calendula," "ex. tiger lily," "ex. jequirity," and boracic acid. Waxham's Tonic Pills Each is made to contain Cinchonidine sulfate gr. 1 Extract of prickly ash gr. Y\ Extract of red cinchona gr. Y\ Extract of dogwood gr. Y\ Capsicum gr. Y\ Wayne's Aphrodisiac Tablets. See Tonic Aphrodisiac Tablets. Weeks' Anti-Constipation Pills. Each pill is stated to contain % grain each of aloin, podophyllin, and extracts of belladonna and nux vomica. Weeks' Little Devils. Each of the "active" pills is stated to contain 1/10 grain each of aloin, compound extract of colocynth and ex- tract of nux vomica, V 5 grain of resin of podophyllin, 1/15 grain of croton oil, and 1/128 grain of oleoresin of capsi- cum. The "mild" pills are stated to contain, each, leptandrin, 1/32 grain; aloin and extract of henbane, each 1/16 grain; podophyllin, 1/6 grain; gamboge, 1/64 grain; and oils of capsicum and pep- permint, each 1/128 grain. Weber's Alpine Tea. According to Hager this is composed of senna leaves, mallow leaves, coltsfoot herb, wood betony, woodruff herb, ar- nica, calendula, yarrow, elder, melilotus, guaiac wood, unpeeled sweet wood, etc. Weinmann's Dental Anaesthetic. This contains about 5 3 A% of cocaine hydrochlorate, also alcohol, oil of pep- permint and iodin (indicating possibly aristol). — Sadtler. Weld's Syrup of Iron Chlorid. See Syrup of Iron Chlorid. Westphal's Auxiliator. According to analysis by the chemist of the New Hampshire Board of Health, this was found to have 3.56% residue on evaporation, glycerin, and borax or boric acid. There was also found 54.8% of alcohol of which one-fifth was wood alcohol. Wheeler's Tissue Phosphates. (Com- pound Elixir of Phosphates and Calisaya.) This is stated to contain bone-calcium phosphate, sodium phosphate, ferrous phosphate, trihydrogen phosphate, and the active principles of calisaya and wild cherry. Wheeler's Nerve Vitalizer. According to an analysis, conducted in the laboratory of the American Medical Association, this was found to contain potassium, sodium and bromin equal in amount to 12.61 g. of potassium bromid and 6.30 g. of sodium bromid in 100 cc. Syrup of licorice is apparently used to disguise the taste of the salts. 876 THE STANDARD FORMULARY White's Eye Water. Contains 1.73% of zinc sulfate, 2% of honey, 2.56% of alcohol, and 0.2% of free acetic acid. — Apoth. Ztg. ; analysis by Dr. H. Weller. White's (Peleg) Salve. Burgundy pitch av. oz. 12 Yellow wax av. oz. 1 — Nelson's Handbook. Whitehead's Spirit of Mustard. According to Hager this is a mixture of Oil of turpentine g. 20 Oil of rosemary g. 10 Camphor g. 5 Spirit of mustard g. 50 Alcohol g. 100 Wickersheimer's Preservative Fluid. There are two such liquids, one in- tended for the preservation of meats and patented in the United States in 1881, consists of 15 g. of common salt, 60 g. of alum, 9 g. of salicylic acid, 45 g. of methyl alcohol, 250 g. of glycerin, and 3 liters of water. The other was patented in Germany and is intended for the preservation of anatomical specimens. It is composed according to Hager, of 60 g. of potash, 25 g. of common salt, 12 g. of saltpeter, 20 g. of arsenous acid, 100 g. of alum, 300 g. of methyl alcohol, 1550 g. of glycerin, and 3 liters of water. Wiesel's Vin Kollerina Comp. (Comp. Wine of Cocoa. (216) According to the manufacturer, this is a compound wine of cocoa with celery, chamomile, and aromatics. Wild Cherry and Morrhualine Cordial. (141) According to the manufacturers' state- ment, each fluidounce contains Calcium hypophosphite gr. 2 Potassium hypophosphite ....gr. 4 Sodium hypophosphite gr. 4 Manganese hypophosphite . .. .gr. 1 Strych. phosph gr. 1/64 Arsenic trioxid gr. 1/64 Fid. wild cherry, sol m.. 16 Extract malt m. 5 Pepsin (1:3000) gr. 2 Morrhuol m. 1 % Glycerin and wine q. s. William's Aphroditic Lymph. (144) This is said to contain the active prin- ciples of fresh bull's testicles and of goat's cord and brain. Winchester's Hypophosphites. This is described as a solution of the hypophosphites of lime and soda with- out syrup. Wine of Cod Liver Oil Comp. See Hostelley's Wine of Cod Liver Oil Comp. Wine of Cod Liver Oil Extract with Cherry and Hypophosphites. (221) This is stated to represent one-fourth its volume of cod liver oil with extract of malt, fluid extract 6i wild cherry bark, and the hypophosphites of lime, sodium, potassium, iron, manganese, qui- nine and strychnine. Wine of Cod Liver Oil Extract with Peptonate of Iron. See Steam's Wine. Wine of Hypophosphites Comp. See Elixir Vigorans. Wine of Mitchella, Compound. (17) This is stated to be composed of mitchella repens, cimicifuga, senecio, vi- burnum pruni folium, and hyosc} r amus formed into a vinous elixir with the fer- mented juice of the fruit of Rhus gla- brum. Wine of Senecio Compound. (36) Each fluidram is stated to represent 10 grains each of senecio aureus and vi- burnum prunifolium, 5 grains each of Hydrastis canadensis and helonias dioica, 8 grains of mitchella repens, 2 grains of cimicifuga racemosa, and 1 grain each of Pulsatilla and conium maculatum seed. Wismol. (30) This is said to be a mixture of mag- nesium peroxid with bismuth oxid. On contact with wound surfaces, oxygen is liberated and hence it has been recom- mended as a substitute for iodoform. It is a fine, white powder, odorless and tasteless, and insoluble in ordinary sol- vents. - PROPRIETARY AND SYNTHETIC REMEDIES. 877 "Wistar's Cough Lozenges. • The following is given by Cooley : Gum arabic av.oz. 2^2 Extract of licorice av.oz. 2Y2 Sugar av.oz. 2^4 Opium, powder gr. 60 I Oil of anise drops 40 For 60 lozenges. The troches of glycyrrhiza and opium, . S. P., contain the same ingredients, but are only about % of the size of the preceding. Wither's Antizymotic Solution. The following contains the same es- sential ingredients as were found by Bierbach's analysis in the original : Corrosive sublimate gr. I Aluminum chlorid gr. Zinc chlorid gr. Potassium chlorid gr. Sodium chlorid gr. Hydrochloric acid m Water to make fl.oz. flinsi's Paper. The following is the formula, accord- g to Hager : Fruit of capsicum annuum. . . .g. Benzoin g. Euphorbium g. Copaiba balsam g. Dragon's blood g. Absolute alcohol g. Macerate the capsicum with the 16 6 6 60 15 16 20 6 2 1 1 120 alco- hol for 3 days and express. To the liquid obtained, add the other ingredients, mac- erate again for 3 days, and filter. Evap- orate the filtrate at a gentle heat to 60 g. This liquid is then spread on thin paper. In using this, strips of the pa- per, slightly warmed, are to be placed over the aching parts. Woodbridge Treatment of Typhoid Fever. This method of treatment of typhoid requires the employment of the three formulas : I. (Tablets.) Podophyllin gr. 1/960 Calomel gr. 1/16 Guaiacol carbonate gr. 1/16 Menthol gr. 1/16 Eucalyptol sufficient II. (Tablets.) Podophyllin gr. 1/960 Calomel gr. 1/16 Guaiacol carbonate gr. l / A Menthol gr . 1/16 Thymol , gr . 1/16 Eucalyptol , sufficient III. (Capsules.) Guaiacol carbonate gr. 3 Thymol gr. 1 Menthol gr. y 2 Eucalyptol m. 5 IV. (Tablets for children.) Podophyllin gr. 1/960 Calomel gr. 1/16 Guaiacol carbonate gr. % Menthol gr. 1/96 Eucalyptol sufficier " V. (Capsules for children.) Guaiacol carbonate gr. y 2 Thymol ..? gr. l / % Menthol gr. 1/16 Eucalyptol m. 1 Olive oil sufficient "Warden's Nasal and Throat Spray — Geolinum Antisepticum. This consists of geoline combined with menthol, eucalyptol and terebene. Wright's Condensed Smoke. This is presumably, like the other preparations of this kind, crude pyrolig- neous acid. Wyeth's Effervescing Headache Salts. See Caf-Acetan. Xanol. (131) This is a name for sodio-caffeine salicylate, which is a white powder free- ly soluble in water, and is decomposed by acids. Xaxa. This is a name for acetylsalicylic acid. Xeroform. (Tribromphenol — Bis- muth.) This is a chemical combination of bis- muthyl oxid and tribromphenol, con- taining nearly 60% of the former. It is a fine, yellow, nearly odorless and taste- less powder. It is insoluble in water, al- cohol, chloroform, and oils, but is solu- ble in 3 T / 2 parts of 2% hydrochloric acid. It is decomposed by alkalies, but not by temperatures below 120 C. so that it may be sterilized. It is stated to be a non-irritant and THE STANDARD FORMULARY non-toxic antiseptic and is recommended as an odorless substitute for iodoform. Internally it is used for cholera infan- tum, dysentery, intestinal tuberculosis, etc., in doses of 15 to 45 grains for adults or 2 to 5 grains for children. Xylol. (Xylene— Dimethylbenzene.) This is a colorless, inflammable liquid. It is given internally in small-pox in doses of 3 to 10 minims, dissolved in oil and made into emulsion or put into cap- sules. Yale's (Mme.) Hair Tonic. According to an analysis by the chem- ist of the New Hampshire Board of Health, this was found to contain 2.09% residue on evaporation, largely glycerin with cinchona alkaloids. The prepara- tion gave a slight reaction for boric acid or borax; no vesicating substance was found. It contained 17% of ethyl alco- hol. Yohimbine. This is an alkaloid obtained from the bark of the Cameroon tree growing in West Africa. It is credited with aphro- disiac properties, being at the same time innocuous. It is marketed in the form of powder and 1/12 grain tablets which latter contain 1/12 grain of the hydro- chlorid. The usual dose is 1 to 3 tablets per day. Zaza's (Mme.) Toilet Cream. When analyzed by the chemist of the Xew Hampshire Board of Health, this was found to contain boric acid or borax, volatile oils, a vegetable gum, probably tragacanth, and glvcerin. Ze-An. (143) This is described as a concentrated fluid extract of corn silk, 8 times the strength of the ordinary fluid extract. Ze-An, Lithiated. Each fluidounce is stated to represent 8 ounces of fresh corn silk and contains also 12 grains each of lithium benzoate and salicylate. Ze-Aseptine. (Ze-An, Forminated.) Each fluidounce is stated to represent 8 ounces of fresh corn silk and 16 grains of hexamethylenamine. Zem^col. (Eczema Colloid.) (148) This is stated to be the extract of the rete mucosum of the healthy yearling lamb, combined with glycerin and salicy- lic acid. Zepp's Dandruff Cure. This is labeled as containing 46% of grain alcohol. The chemist of the Xew Hampshire Board of Health found it to contain a small amount of borax, can- tharides, and glycerin. The total solids amounted to 2%. Zinc Permanganate. This is in almost black hygroscopic crystals very much resembling those of the potassium salt, and is readily soluble in water. It is an antiseptic and disin- fectant. It is used as a collyrium in a strength of 1 or 2 to 1000 and as an in- jection in gonorrhea, 1:4000. It must not be mixed with organic matter as an explosion may occur. Zinc Perhydrol. (130) This is a compound containing 50% of zinc dioxid and 50% of zinc oxid. It is a white powder, insoluble in water but decomposed by acids with liberation of hydrogen peroxid. It is applied to wounds and ulcerating surfaces, and has the advantage over sodium dioxid that the product of decomposition is not a caustic substance but the inert zinc oxid. It is applied as a dusting powder or in 10% ointment. Zinc Sulfocarbolate. This is in colorless or faintly pinkish crystals, odorless, of a slight metallic taste, and very soluble in water or alco- hol. It is used internally as an intes- tinal disinfectant and externally for gon- orrhea or wounds in V2 to 1% solutions. The dose is about 2 grains. Zinol. This is stated to consist of 1 part of zinc acetate and 4 of "albumin naphtho- sulfonate." It is recommended in the PROPRIETARY AND SYNTHETIC REMEDIES. 879 treatment of gonorrhea by injection in the proportion of 12 to 24 grains to the pint. Zoa-Phora Eemedies. Zoa-Phora itself is stated to contain 15% of alcohol, the pile cure x /z grain of opium to each suppository and the "vit- alizing cones" % grain of opium to each suppository. Zomol. This is described as an antituberculous serum of desiccated muscular plasma representing 200 times its weight of raw- meat. Zoolak. (55) This is the fermented milk food for- merly sold under the name matzoon. Zumo-Anana. (233) This is described as a pineapple diges- tive wine containing 50% of ripe pine- apple juice and its proteolytic ferments in a concentrated form. Zymin. This is described as a dried, sterilized yeast intended for medicinal purposes. Zymocide. (167) This is stated to contain colorless ex- tract of golden seal, colorless extract of calendula, extract of witch hazel, zinc sulfocarbolate, boracic acid, thymolate of soda, menthol, oils of wintergreen, spearmint and eucalyptus, and 18.14% of alcohol by volume (1473% by weight). Zymoidin. This is an antiseptic said to be com- posed of oxids of zinc, bismuth and aluminium with iodin, boric, carbolic, gallic and salicylic acids, quinine, etc. — Coblentz. Zymphene. Chemically this is sodium metaoxycya- nocinnamate. It is in yellowish crystals, soluble in water or alcohol. It is used as a tonic and digestive stimulant, espe- cially in loss of appetite. The dose is 8 grains. REFERENCE LIST The following list gives the names of manu- facturers whose products are mentioned in Part III. The number preceding the name and address corresponds to the number follow- ing the name of the preparation. 1. Abbott Alkaloidal Co., Chicago, 111. 2. Allen & Hanburys, London, Eng. 3. Alphazol Co., New York, N. Y. 4. Alta Pharmacal Co., St. Louis, Mo. 5. Amenorott Co. 6. American Therapeutic Co., New York N. Y. 7. Angier Chem. Co., Boston, Mass. 8. Anglo-American Phar. Co., New York, N. Y. 9. Anhydrosine Co., Denver, Col. 10. Antibrule Chem. Co., St. Louis, Mo. 11. Antisapron Chem. Co., Henderson, Ky. 12. Argol Co., Danbury, Conn. 13. Arlington Chem. Co., Yonkers, N. Y. 14. Armour & Co., Chicago, 111. 15. Armstrong Mfg. Co., Boston, Mass. 16. Attfleld Chem. Co. 17. Baker & Co., Chicago, 111. 18. Barnes & Hille, Philadelphia, Pa. 19. Battle & Co., St. Louis, Mo. 20. Bell & Co., New York, N. Y. 21. Biersdorf & Co., Hamburg, Ger. 22. Billings, Clapp & Co., Boston, Mass. 23. Binz, E. G., Los Angeles, Cal. 24. Bioplasm Co., New York, N. Y. 25. Bishop, A., London, Eng. 26. Boehringer & Sons, New York, N. Y. 27. Bovril Co., London, Eng. 28. Boraline Chem. Co., Baltimore, Md. 29. Bristol-Myers Co.. New York, N. Y. 30. Buchlos, Frankfort, Germany. 31. Burrough Bros.. Baltimore, Md. 32. Burroughs, Wellcome & Co., London, Eng. 33. Cathcart & Force Co., Newburgh, N. Y. 34. Cassia Drug Co., Los Angeles, Cal. 35. Central Chem. Co., New York, N. Y. 36. Chapman Mfg. Co., Chicago, 111. 37. Chem. & Elect. Co., New York, N. Y. 38. Cherry, W. W., Trenton, N. J. 39. Chesebrough Mfg. Co., New York, N. Y. 40. Chira Chem. Co., Louisville, Ky. 41. Citrosandalene Co., New York, N. Y. 42. Citrozon Lab., Cologne, Germany. 43. Claflin & Co., Providence, R. I. 44. Clin & Co., Paris, France. 45. Clinton Phar. Co. 46. Cloftlin Chem. Co., New York, N. Y. 47. Codliver-Glycerine Co., St. Louis and New York. 48. Combs Chem. Co.. St. Louis, Mo. 49. Converse Chem. Co.. St. Louis. Mo. 50. Cortexalin Co., New York. N. Y. 51. Cosmos Chem. Co., New York. N. Y. 52. Crowell, Rufus, & Co.. New York. N. Y. 53. C. & P. Chem. Co., Chicago, 111. 54. Dad Chem. Co., New York. N. Y. 55. Dadirrian, New York, N. Y. 56. Daniel, J. B.. Atlanta, Ga. 57. Davis Phar. Co. 58. Dawson Phar. Co.. Dawson Springs. Ky. 59. Decary, A.. Montreal, Canada. GO. Delta Diphthero Co., Evansville. Ind. 61. Denver Chemical Co.. New York. N. Y. 62. Dieterich E., Helfenberg, Germany. 63. Dinet & Delfosse. Chicago, 111. 64. Dios Chem. Co.. St. Louis, Mo. 65. Echino Chem. Co. 66. East Ave. Drug Co.. Cleveland. 0. 67. Elmer & Amend. New York. N. Y. 68. Eumetra Phar. Co.. Detroit. Mich, 69. Ensoma Phar. Co.. Cincinnati, O. 70. Fuircbild Bros & Foster, New York, N. Y. 880 THE STANDARD FORMULARY 100. 101. 102. 103. 104. 105. 106. 107. 108. 109. 110. 111. 112. 113. 114. 115. 116. 117. 118. 119. 120. 121. 122. 123. 124. 125. 126. 127. 128. 129. 130. 131. 132. 133. 134. 135. 136. 137. 138. 130. 140. 141. 142. 143. 144. 145. 146. 147. 148. Ferrol Med. Co., Markham, Ont. Fltchmul Co., Concord, N. H. Flint, J. G., Decatur, 111. Forbes Diastase Co.. Marietta, O. Foster, Dack Co., Chicago, 111. Fraser & Co.. Philadelphia. Pa. Fries Bros., New York, N. Y. Gardner, R. W., Orange, N. J. Gardner-Barada Co.. Chicago, 111. Girard Chem. Co., Philadelphia, Pa. Goat Lymph Sanitarium Assn., Chicago, 111. Goshen Pharmacal Co., Goshen, Ind. Grape Capsule Co., Allentown, Pa. Gray, Toronto, Canada. Grosvener & Co.. Boston, Mass. Hull Bros. & Co., Kalamazoo, Mich. Halsey Bros., Chicago, 111. Hance Bros. & White, Philadelphia, Pa. Hancock, J. F., Baltimore. Md. Hart, E. J. & Co.. New Orleans. La. Hartz, The J. F. Co., Detroit and Toronto. Harvey. G. F. Co., Saratoga Springs, N. Y. Harvey & Co., Saratoga Springs, N. Y. Hayes Phar. Co., Phoenixville. Pa. Helfenberg Chem. Works. Helfenberg, Ger. Henry Pharmacal Co.. Louisville, Ky. Hoffman-Laroche Co., New York, N. Y. Hood & Co.. Lowell. Mass. Johnson, M. & Co.. Jersey City, N. J. Jordan & Co., Charlotte, N. C. Kahama Chem. Co., Erie, Pa. Kalle & Co. Katharmon Chem. Co., St. Louis, Mo. Keasbey & Mattison. Ambler, Pa. Keimol Chem. Co., Baltimore, Md. Kenyon Chem. Co. Killgore, Chas., New York, N. Y. Knoll & Co.. New York, N. Y. Kornitzer. Vienna, Austria. Kremers & Urban Co.. Milwaukee. Wis. Kress & Owen Co., New York, N. Y. Lambert Phar. Co., New York, N. Y. Lavoris Chem. Co.. Minneapolis. Minn. Lehn & Fink, New York, N. Y. Liberty Chem. -Co., Philadelphia. Pa. Lilly. Eli & Co.. Indianapolis, Ind. Lloyd Bros.. Cincinnati. O. Loring & Co., New York. N. Y. McCoy-Howe Co.. Indianapolis. Ind. McKesson & Robbins. New York. N. Y. Mallinckrodt Chem. Works. St. Louis, Mo. Maltbie Chem. Co.. New York, N. Y. Maltine Co., Brooklyn. N. Y. Malt-Diatase Co., New York, N. Y. Manola Co.. St. Louis. Mo. Marchand. Chas., New York, N. Y. Martindale. W., London, Eng. Mercer Chem. Co., Trenton. N. J. Merck & Co., New York. N. Y. Merrell. Wm. S. Chem. Co*.. Cincinnati. 0. Metcalf. Theodore & Co.. Boston, Mass. Meyer Bros.. St. Louis. Mo. Miller, T. A.. Richmond, Va. Milliken & Co.. St. Louis. Mo. Mitchell. C. L.. Philadelphia. Pa. Morgan. T. C. & Co., New York. N. Y. Morgan Co., The same as procedinff. Morris. Zahn & Co.. Berlin, Ger. Morse, Hazen. New Rochelle. N. Y. Mulford Co.. H. K., Philadelphia. Pa. National Pharmacy Co.. Oakland. Cal. Nelson. Baker & Co.. Detroit. Mich. New Animal Therapy Co.. Chicago, 111. N. Y. Phar. Ass'n. Yonkers. N. Y. North Chem. Co.. Peoria. 111. Norway Phar. Co.. Now York. N. Y. Norwich Pharmacal Co., Norwich, N. Y. 149. Nourry, J., France. 150. Nu Tone Co., Lowell, Mass. 151. Nutrolactis Co., New York, N. Y. 152. Oakland Chem. Co., New York, N. Y. 153. Ophthalmic Remedy Co. 154. Osborn-Colwell Co., New York, N. Y. 155. Oxychlorine Chem. Co., Chicago, 111. 156. Ozomulsion Co., New York, N. Y. 157. Ozomuro Chem. Co., Omaha, Neb. 158. Palisade Mfg. Co., Yonkers, N. Y. 159. Parke, Davis & Co., Detroit, Mich. 160. Patch, E. L. & Co., Boston, Mass. 161. Pearson Co., Germany. 162. Peter-Neat-Richardson Co., Louisville, Ky. 163. Pheuique Chem. Co., St. Louis, Mo. 164. Phillips Co., C. H., New York, N. Y. 165. Pulvola Chem. Co., New York, N. Y. 166. Red Chem. Co. 167. Reed & Carnrick, New York, N. Y. 168. Reichelt, Breslau, Germany. 169. Reighter, F. C, Chicago, 111. 170. Resinol Chem. Co., Baltimore, Md. 171. Rex Pharmacal Co. 172. Riedel, Berlin, Germany. 173. Rio Chem. Co., St. Louis. Mo. 174. Roessler & Hasslacher, New York, N. Y. 175. Rump & Lehners, Hanover, Germany. 176. Russell & Lawrie, Tarrytown, N. J. 177. St. Louis Phar. Co.. St. Louis, Mo. 178. Schering. Berlin, Germany. 179. Schieffelin & Co., New York, N. Y. ISO. Schlotterbeck & Foss Co., Portland, Me. 181. Searle & Hereth Co., St. Louis. Mo. 182. Seydel & Rodgers, St. Louis, Mo. 182a. Sharp & Dohme, Baltimore. Md. 183. Smith. Martin H., New York, N. Y. 184. Squibb, E. R. Co., Brooklyn, N. Y. 185. Squire & Sons, London, Eng. 186. Standard Chem. Co., Broklyn. N. Y. 187. Stearns, Fred'k. & Co.. Detroit. Mich. 1S8. Stearns & White Co., Chicago, 111. 189. Strong, F. H. Co., New York, N. Y. 190. Strong. Cobb & Co.. Cleveland, 0. 191. Stroschein, I. E., Berlin, Germany. 192. Sutliff & Co., Peoria. 111. 193. Theller, New York. N. Y. 194. Tilden Co.. New Lebanon, N. Y. 195. Trades Chem. Co. 196. Truax, Greene & Co.. Chicago. 111. 197. U. S. Ferrol Co.. Buffalo. N. Y. 198. U. S. Pharmacal Co. (Texasl. 199. Upjohn Co., Kalamazoo, Mich. 200. Valley Chem. Co., Danbury. Conn. 201. Van Horn & Co., New York, N. Y. 202. Vass Chem. Co., Danbury, Conn. 203. Veroform Hygienic Co., New York, N. Y. 204. Vial, Paris, France. 205. Viburnal Chem. Co., Madison. Wis. 206. Vigorans Chem. Co., St. Louis. Mo. 207. Virginia Pharm. Co., Richmond. Va. 2\S. Walker-Green Phar. Co., Kansas City, Mo. 209. Walker Phar. Co., St. Louis, Mo. 210. Wallau. G. J.. New York. N. Y. 211. Wampole & Co., Philadelphia, Pa. 212. Warner. Wm. R. & Co., Philadelphia. Pa. 213. Washington Chem. Co., Washington, D. C. 214. Waterburv Chem. Co.. Des Moines. la. 215. Weeks, D. & C. Co.. Jackson. Mich. 216. Wiesel. Baltimore. Md. 217. Winslow Laboratory. New York, N. Y. 218. Wood & Flint. Decatur, 111. 219. Woodruff, I. O. & Co., New York, N. Y. 220. Worden, C. E. 221. Wyoth & Bro., Philadelphia. 222. Zimmer & Co., Frankfort, Germany. 223. Zumo Phar. Co., St. Louis, Mo. Part IV. PERFUMES AND TOILET ARTICLES HISTORICAL NOTES. The first perfume was the fragrant flower and it still continues to be the favorite despite all the artificial com- binations that man has designed. The use of perfumes, cosmetics, hair dyes, etc., dates back as far as recorded his- tory. The Orient and Egypt were the cradle of the art of perfumery and of the use of cosmetics, etc., although there is ap- parently no record of their use among the Chinese and Japanese. The Egyptians and Phoenicians and earlier peoples em- ployed perfumes and cosmetics. Among these people as among the people of to- day, pleasing odors were used, the face and body were ornamented or beautified or oiled, the hair was colored, frizzed, etc., and similar arts were in vogue. The Jews learned these arts from the Egyptians during their stay in Goshen but they never became as extravagant in their use as the latter. The Bible con- tains many references to incense but the Jews employed this mainly for religious purposes, incense being burned in the synagogues in censors, a custom still continued by the Catholics today. The Greeks were also adepts in the use of perfumes and cosmetics. The Romans were the pupils of the Greeks in these arts as well as in others and dur- ing the consulates and empire, the use of these substances was carried to ex- tremes, so much so that laws were pass- ed against them. When the almost savage Huns and Goths swept down over Rome, the use of perfumes and cosmetics almost ceased in Europe. At this time, however, the Arabian empire rose to prominence both as a na- tion and in the arts and sciences. The Arabs, the ancient masters of chemistry,, were also versed in the manufacture oi perfumes and cosmetics. A number of books on these subjects were written by Arabians during the tenth and eleventh centuries. Intercourse with the Orient brought about by the Crusades again made Euro- peans familiar with the art of perfum- ery. Italy and France, in those days the representatives of culture, were the countries in which the preparation of perfumes and cosmetics was carried on on a large scale. A member of a Ro- man family by the name of Frangipanni invented the perfume bearing this name. In England, perfumes and cosmetics were not in general use until the reign of Queen Elizabeth. She apparently used these substances in great abundance, and the people soon followed the example of the. court. In fact to such extent were they used that Parliament passed an act in 1770 that if a woman of whatever age or rank, be she maid or widow, beguile any man and inveigle him into matri- mony by the use of perfumery, false hair, corsets, hooped petticoats, high heels, or false hips, she shall suffer the penalty of the law and the marriage shall be null and void. CHAPTER I. DISTINCTIVELY ODOR PREPA- RATIONS. These are preparations used mainly or largely for their odor include Handker- chief Extracts, Sachet Powders, Solid Perfumes, Pot Pourris, Fumigating Pas- tilles, Powders, etc.; Cologne Waters, Toilet Waters, Bay Rum, Toilet Vine- gars, and Smelling Salts. Fine perfumes can be prepared only by the use of good material; in fact, the S83 THE STANDARD FORMULARY best obtainable is none too good for a discriminating taste. In the following paragraphs will be outlined the requisites of the best materials. EXTRACTION OF FLOWER ODORS. Flower odors are extracted in various ways, depending on the volatility or the relative proportion of the particular odor to be captured, and in numerous in- stances more than one method is used for extracting the same odor. Curiously enough, an odorous oil extracted by one method does not always smell the same as when extracted by another method. For example, oil of rose obtained by dis- tillation is not the same as when ex- tracted by the more delicate process of enfleurage or by means of volatile solv- ents. The application of heat during distil- lation causes chemical changes such as hydrolysis of various delicate constitu- ents and the water absorbs or dissolves some of the ingredients which are there- fore lost to the oil. Oils of rosemary, thyme, lavender, geranium, rose and orange flozi'ers are obtained by distillation of the flowers, or, in the case of roses, of the petals alone, with water, this being the most ancient method of obtaining these prin- ciples. Upon standing, the oil floats out on the surface of the distillate while the water may be used again for distilling more oil or it may be sold in the mar- kets as an aromatic water. Process 2. For Extraction of Odors. — If, instead of distilling the flowers with water, they are placed on glass plates in wooden frames (resembling window sashes) with thin layers of pur- ified lard, or lard and suet, the proc- ess is called enfleurage. A number of these frames are also placed on top of one another, and every day fresh flowers arc placed upon the fat until the latter is saturated with perfume. These per- fumed fats, known as pomades (pom- mades in French), are sent into the market in different degrees of saturation which are indicated by numbers, viz., 8, 12, 16, 30, etc. Rose petals and the flow- ers of the orange, jasmine, tuberose, cas- sie, violet, mimosa, heliotrope, reseda or mignonette, and jonquille are treated in this manner. Delicate floral odors are extracted in this manner which would be ruined by the heat of distillation. The odorous principles are subsequently extracted from the pomade with alcohol which dissolves out the perfume from the mix- ture of odor and fat. Process 3. — Still another method of extraction of floral odors is that of hot maceration in which the flowers are im- mersed and paddled in purified lard which is kept melted and hot. The flow - ers are separated from the lard by straining and all the fat is removed by subjecting them to pressure. Roses, orange flowers, cassie blossoms and vio- lets are extracted in this manner. Process 4. — A German firm extracts these flowers with a purified paraffin oil, from which the perfume is to be ex- tracted by agitation with alcohol. The perfumed oil is of unlimited permanency and entirely free from rancidity, and the residue after extraction with alcohol may be used for making hair oil and for other purposes. Other oils, such as olive oil, are also used for the extraction of flower odors. Such impregnated oils have been known "huiles antiques," lat- terly as "huiles aux fleurs." The per- fume may be extracted, as already stat- ed, by agitation with alcohol and subse- quent decantation of the spirituous li- quid. Process 5. — This method is an entirely modern one and consists in extracting the odoriferous principles by means of an inodorous (or nearly so) volatile solvent which is subsequently distilled off in a vacuum and is used over again for the same purpose. The perfume re- mains behind in a solid or semi-solid form known as a "concrete oil" or "solid essence." The idea of this process is credited to the chemist Robiquet as early PERFUMES. 883 as the year 1835. Among the solvents used are methyl chlorid, carbon disulfid, chloroform, ether, acetone and petroleum ether. The solvent must leave no resid- uary odor of its own and must there- fore be highly purified for this purpose. In this process the perfume remains be- hind mixed with waxy, fatty and color- ing matters extracted by the solvent. This process of extraction of flower odors has now been improved so that even the waxy and fatty matters are eliminated and the liquid essence, or what is practically the absolute odor of the flower, is now in some cases availa- ble. The particulars of these improved processes are usually either secret or patented. These absolute essences are exceed- ingly expensive, a kilogram of absolute essence of violets being quoted at about 15,000 francs (nearly $3,000). For con- venience these essences are marketed in the form of alcoholic solutions of such strength as to correspond to the con- crete essence. These essences being so very costly are all usually sold in the form of either solid or liquid dilutions, the former being the usual concrete es- sence of the market. Process 6. — This method of extracting flower odors is by what is known as the pneumatic method. Air or carbonic an- hydride is blown over the flowers onto glass plates coated with lard which lat- ter retains the perfume. This method has not, however, proved satisfactory: It will be observed that frequently the same flowers are extracted by different processes. The odor is inclined to vary according to the process, that by distilla- tion being the least -fragrant but at the same time the most tenacious or endur- ing. The price of the product also varies in accordance with the fragrance and the yield. The variation in odor very widely, of course, augments the capacity of the perfumer to produce perfumery products. 56 ESSENTIAL OILS. It is in the case of volatile oils that the greatest difficulty is experienced in securing first-class material. They should not only be free from adulterations but should be of the very best grade as there is the greatest variation in the quality of essential oils. Adulteration of these oils are very frequently prac- ticed and with the utmost ingenuity to defeat attempts at detection. In the case of oils containing stearop- tens, spermaceti is used as an adulterant. Purified kerosene is also used, also res- ins, alcohol, rectified oil of turpentine, various other mixtures, and very com- monly cheaper or inferior grades of oil of the same kind. The tests for adulteration are usually the polariscope and solubility in alcohol, full strength or diluted. The utmost care should be taken to preserve these oils. They should be kept in small, well-stoppered bottles, preferably in a cool and dark place. All of them decompose in time, the odor be- ing altered materially. Not all volatile oils used for perfum- ery purposes are obtained from flowers. Some precious and useful oils are ob- tained from herbs, roots, fruit rinds, woods, etc., such as the oils of orris, orange, lemon, cedrat, bergamot, pat- chouly, vetivert, geranium, etc. Only such essential oils are here men- tioned as are obtained by such processes as expression and distillation and are placed on the market in the isolated state. Those that are extracted by the process of enfleurage and maceration in oils and require subsequent treatment of the fat with alcohol are referred to un- der the pomades. Oil of Bitter Almond is now obtaina- ble deprived of hydrocyanic acid, and owing to the excessively poisonous char- acter of the latter such an oil should be preferred for perfumery purposes. The artificial oil known as benzaldehyde when purified may advantageously re- S84: THE STANDARD FORMULARY place the natural oil. It contains, of course, no hydrocyanic acid. It is now recognized by the U. S. P. This should not be confounded with the so-called oil of mirbane (nitrobenzol or nitroben- zene) which has a resemblance in odor to oil of bitter almonds but is totally unfit for perfumery purposes. Oil of Bay is an oil used almost ex- clusively for the manufacture of "bay rum." It contains eugenol which re- minds of oil of cloves and terpenes which remind of oil of pimento. It is soluble in about an equal quantity of alcohol, becoming less soluble on stand- ing, due to oxidation of the terpenes. Concurrently the oil becomes thicker and darker. Oil of Bcrgamot can usually be ob- tained of good quality and it is quite permanent. It owes its virtues mainly to linalyl acetate; it also contains lina- lool. It is adulterated with oils of tur- pentine, orange, or inferior grades of bergamot. Of the Oils of Lavender Flowers, the English, or so-called "Mitcham," is the most highly esteemed owing to the larger proportion of linalyl acetate present. They also contain linalool and cineol. Oil of Lin aloe is obtained by the dis- tillation of the wood of plants growing in Mexico and Guiana. Its main con- stituent is linalool which is readily con- verted into linalyl acetate, the main con- stituent of oil of bergamot. Oil of Rose Geranium (or Pelargon- ium) is of considerable importance as it has an odor similar to that of rose and the distillers and dealers in oil of rose have no hesitancy in adding oil of rose geranium to it. Curiously this latter oil is itself notably subject to adulteration, the principal adulterant being "palma- rosa oil" or "oil of ginger-grass," which has a very similar odor. The principal constituent of both palmarosa and rose geranium oils is geraniol or rhodinol which is itself now an article of com- merce. Oil of rose geranium is derived by distillation of the leaves. The best kinds are the French and Spanish oils, the so-called African and Algerian being of inferior quality. Oil of Neroli or Orange Flowers is of several varieties. What is called Oil of Neroli Bigarade is derived from the flowers of the bitter orange, Oil of Neroli Portugal from the flowers of the sweet orange. The oils are not entirely alike, the Bigarade being much finer in odor and being more expensive. Oil of Neroli Petale is a superior grade of the Bigarade oil. A much inferior oil de- rived by distillation of the leaves, twigs and unripe fruit of the bitter orange tree is known as Oil of Petitgrain. It is too coarse for use in any fine perfum- ery. It is said that hardly any pure arti- cle reaches the market, the so-called "genuine oil" being a mixture of l A real oil, Y% oil of bergamot, and Y& of petit- grain oil. It is used in making cologne water. Of the various kinds of Oil of Clove, that known as the Bourbon is most highly esteemed. The main constituent is eugenol, which is now an article of commerce and is recognized by several pharmacopeias. Lemon and Orange, the two citrine oils, are very frequently adulterated and are very prone to decomposition. These oils on keeping become thickish and ac- quire a terebenthinate quality which precludes their use from any purpose whatever. They should be preserved like other oils in small, well-stoppered bottles in a cool place. An excellent suggestion is to add 5 or 10% of alcohol to the fresh oil, which assists in keeping the oils in good condition. They are adulterated with alcohol or oil of tur- pentine. The three fruit oils, bergamot, lemon and orange, are obtained from the rinds of the fruits by breaking open the oil cells on the surface of the fruit and absorbing the oil with a sponge. In- ferior grades of oil are obtained by dis- tillation. The main constituent of lemon oil is citral, which is also an article of commerce. For commercial purposes, PERFUMES. 885 citral is derived from another oil, viz., oil of lemon-grass. Oil of Citron, another fruit oil, is more commonly known as Oil of Cedrat, and is derived from the rind of a fruit similar to the lemon. It is similar to oil of lemon but is of a much richer and more fragrant odor. Oil of Rose, frequently called otto or attar of roses, is obtained in South- eastern Europe by distillation of rose petals with water. Owing to the small amount of oil they contain, only about one pound to 3,000 pounds of petals, the oil is excessively expensive and this sub- jects it to the grossest adulterations. The main constituent is the stearopten and this accounts for the frequent adul- teration with spermaceti. Oil of rose geranium is also a common adulterant. Rose is a very popular odor and conse- quently there are many varieties of rose perfumes, besides being a constituent of many other combinations of odors. It is often possible to replace rose partially with rose geranium but this must be done judiciously and is more advantage- ous in the case of the weaker perfumes like the toilet waters. Oil of Sandalwood is largely adulter- ated, usually with castor and other fixed oils. Various mixtures of other oils have posed as santal oil. The best oil is the so-called "English" or East India oil, which should contain nearly 90% of san- talol. Oil of Cedarzvood or Red Cedar is like oil of santal an example of a vola- tile oil derived from a wood. The kind of cedarwood which furnishes this oil is the same as that used for cigar boxes and lead pencils, not the white cedar of the northern regions which furnishes an oil of too great similarity to turpentine to be available for perfumery purposes. The kind known as Florida oil of cedar- wood is to be preferred for the manu- facture of perfumes. Oil of Patchouli is a thick, dense oil derived by distillation of the leaves (and, in inferior grades, of the stems) of an East Indian plant. Oil of cubeb and cedar are frequent adulterants. In a concentrated state it possesses a dis- agreeable odor, a characteristic of many other essential oils, but in a diluted state is tolerably fragrant. It is added to per- fumes mainly to impart stability to the odor. Oil of Vetivert, like oil of patchouli, comes from India., It is derived by dis- tillation of the rhizome of a large grass called vetivert or kus-kus. Also like patchouli oil, it is of a thickish consist- ency and it lacks fragrance in concen- tration. When mixed with flower odors it imparts permanence to the latter. Oil of Ylang Ylang or Ihland Ihlang is derived from the islands of Luzon and Borneo. This word signifies in Tagal language "flower of flowers." The flowers yield the oil upon distillation. The first portions of distillate are sold as oil of ylang ylang, the later portions as Oil of Cananga (or Kananga). The first has a much finer odor and is much more expensive. Oil of Ceylon Cinnamon is the most highly esteemed of the oils of cinnamon. It is stated that a true cinnamon oil sel- dom reaches the market, the commercial oil being derived by distilling the peel- ings of the bark and the leaves. It is usually weak in cinnamic aldehyde, its principal constituent, of which it should contain not less than 75%. Oil of Orris is obtained by distillation of orris root with steam. Some claim that the oil does not pre-exist in the root but is developed during distillation. The yield is very small, having been variously stated to be from 1/10 to 8/10%. The product obtained is a semi- solid mass which is called "orris butter" or "concrete oil of orris" and contains 85% of myristic acid, an odorless sub- stance. When the latter is removed the residue is known as "concentrated or liquid oil of orris," and it consists main- ly of the principle irone, which is the ultimate odorous principle of orris root. Irone is itself an article of commerce. 88G HE STANDARD FORMULARY The oil of orris referred to in the for- mulas in this book is the liquid oil. Much of the liquid oil of the market is simply a solution of the concentrated oil in alcohol. Owing to the small yield it is exceedingly expensive and it is used sparingly in mixtures. Its odor is simi- lar to that of violets and it is used in mixtures as a substitute for and for strengthening the natural odor of the latter. Some oils of orris of the market are stated to be merely mixtures of cedar and other oils with true oil of orris. Oil of Mignonette Flowers, or Reseda, is a dark oil and like concrete oil of orris is solid at ordinary temperatures. Oil of Verbena is obtained by distilla- tion of the leaves of the lemon verbena but on account of its scarcity and high price it is almost entirely displaced by Oil of Lemongrass, a very similar oil. Oil of Rosemary is of two kinds, French and Italian or, more properly, Dalmation. The former is much finer and is the higher priced. Commercial "Oil of Jasmine/' as it has appeared on the market, has been simply the alcoholic washings of jas- mine pomade. True oil of jasmine is also obtainable but it is exceedingly ex- pensive. In its place may be used the artificial or synthetic oil which is now an article of commerce. Another similar synthetic oil is Oil of Cassie. TERPENELESS OILS. The volatile oils are complex bodies, being composed of a great variety of constituents such as hydrocarbons, alco- hols, aldehydes, ketones, phenols, esters and some sulfur compounds. The hy- drocarbons (bodies consisting of hydro- gen and carbon only) present are of the class known as terpenes, consisting of the terpenes proper, the sesquiter- penes, diterpenes, triterpenes, etc. These terpenes are characterized by lack of aroma and very sparing solubility in di- luted alcohol and the ease with which they become oxidized and resinified in the presence of air, light and moisture, while the remaining constituents are (mostly) the true odor carriers. It fol- lows that if terpene-bearing volatile oils, which include practically all essential oils, be deprived of terpenes, the product will be greatly improved. A number of such terpeneless, or so-called concen- trated, volatile oils are now commercial- ly available. These terpeneless oils are not readily changed upon exposure, are readily solu- ble in dilute alcohol, and the aroma is purer and more delicate. On account of the lower boiling point of terpenes, these are readily removed by the process of fractional distillation. Among the terpeneless oils of the market are oils of lemon, orange, laven- der, caraway, clove, anise,- coriander, peppermint, sassafras, eucalyptus, etc. All volatile oils do not, however, con- tain sufficient terpene to make it an ob- ject to remove it. These terpeneless oils must not be confounded with the iso- lated oxygenated components, such as citral, for instance, which is sometimes sold as "terpeneless lemon oil." CONCRETE OILS. The so-called "concrete oils," also known as "concrete essences" and "con- centrated flower oils" and less appro- priately as "concrete perfumes," are de- rived, as already explained under Ex- traction of Flower Odors, by extraction of the flowers with a volatile solvent and subsequent evaporation of the solv- ent, except concrete oil of orris, which is obtained by distillation of orris root. One pound of concrete oil will often re- place ioo pounds of pomade made by the enfleurage process. Among the con- crete oils, other than oil of orris, which are now commercially available are those of cassie, rose, tuberose, mignonette, lilac, violet, and heliotrope. Concrete oil of orris is described under Essential Oils. These oils are not entirely soluble in alcohol, owing to the presence of waxy and fatty matters. PERFUMES. 887 Owing to the highly concentrated and expensive character of these oils, they are usually placed on the market in the form of alcoholic solutions or of mix- tures with wax. The latter must be treated with alcohol to extract the odor- ous principle. CHEMICAL PREPARATIONS AND SYNTHETIC PERFUMES. The chemical preparations used in per- fumery manufacture, including the syn- thetics employed for this purpose, may be classed into those extracted .or iso- lated from other substances such as vol- atile oils, and those obtained by syn- thesis. A familiar example of the for- mer is menthol, of the latter, vanillin. This distinction is, however, not accu r rately drawn because many principles formerly obtained by separation from a mother substance are now prepared syn- thetically, vanillin itself being an exam- ple. Even some of the essential oils formerly obtained exclusively by natural means are now prepared artificially. The study of volatile oils in the last decade has given chemists such a knowledge of their constitution that they are able to assemble the constituents, taken from various other source's, and thus produce a duplicate of the natural perfume. Such products are the artificial oils of ylang ylang, cassie, and jasmine. The number of synthetic perfumes is now quite great and is constantly in- creasing. Not only are the natural odors imitated but entirely new odor products have been made, thus greatly widening the range of possible combinations of odors. These synthetic substances are made by processes which in most instances are secret or patented, and very frequently the same substance is known by a gre'at variety of names, each manufacturer having a different set of names for many of his products from those used by other manufacturers. These synthetic products are not used entirely for making perfumery and toilet articles ; they are used also for making flavoring extracts, liqueurs or cordials, and soaps. Inferiors or coarser kinds are generally employed for perfuming soap. Artificial Musk was one of the earliest synthetic perfume products. It lacks the stability or fixing power of the natural substance, but it serves an excellent pur- pose and is much less expensive than true musk. It is frequently specified in perfume formulas as "musc-Baur." Vanillin and Cumarin were also early products of the synthetic chemist's skill. The former is naturally present in va- nilla but L made synthetically from coniferin (from pine wood) and from eugenol. Cumarin is the active principle of tonka beans but is also present in many plants, being widely distributed through- out the vegetable kingdom (clover, deer's-tongue, woodruff, etc.). It is pre- pared artificially from salicylic anhy- dride. It has the scent of new-mown hay. Foin Coupe, so-called, is a commercial product sold for the preparation of the scent of new-mown hay. It appears to be a mixture consisting mostly of cuma- rin. Eugenol is a prominent constituent of oil of clove and is also present in the oils of bay, pimento, and sassafras. It is the starting point in one process for the manufacture of artificial vanillin and various other substances. It is now recognized in the U. S. and German Pharmacopeias. Citral is among the best known prod- ucts which are isolated from other sub- stances. It is the active principle of oil of lemon, which for commercial pur- poses is derived from oil of lemon-grass which contains it more abundantly. Geronil is a constituent present in several oils, such as oils of citronella, linaloe, verbena, rose, rose geranium, and palmarosa, and in small amounts in many other oils. For commercial pur- poses, it may be separated from the ,chcapest of these, such as oil of citron- 888 THE STANDARD FORMULARY ella. Artificially it is prepared from cit- ral or linalool. Citronellol is also present in the same group of oils but these ingredients are present in different proportions and there are many other modifying con- stituents in the various oils to account for the differences in odor. Citronellol is made artificially from citronellal, still another constituent of oil of citronella. Combinations of geraniol and citronellol have an odor of rose and are used as substitutes for oil of rose under the names Rhodinol and Roseol. Linalool is a substance present in oils of linaloe, bergamot, neroli, lavender, thyme, and ylang ylang. It is also made artificially from geraniol and it is the source of Linalyl Acetate, the principle constituent of oil of bergamot. What is sold in the market as Berga- miol is linalyl acetate. Cinnamic Aldehyde is obtained by separation from oil of cinnamon, of which it is the main constituent. Syn- thetically it is prepared from a mixture of benzoic and acetic aldehydes. It is usually sold as "artificial oil of cassia" and it is purer and more reliable than the commercial oils. The corresponding alcohol, Cinnamyl Alcohol, is a synthetic possessing the odor of hyacinths and also of the mea- dowsweet. Benzaldchyde or Benzoic Aldehyde is another aldehyde used for perfumery and flavoring purposes. It is a substi- tute for essential oil of bitter almonds. It is now recognized by the U. S. Phar- macopeia. Aubcpine or Anisic Aldehyde is an- other aldehydic perfume which is made artificially from phenol and from oil of anise or its constituent anethol. It is in two forms, liquid and crystal ; the for- mer is soluble and is used in liquid per- fumes, the latter is insoluble and is used in sachet powders, etc. The liquid oxi- dizes readily when exposed to air to anisic acid and therefore should be kept in well-closed bottles. It has the odor of the hawthorn and may-blossom. A similar synthetic product is known as Crategine. lonone is probably the most interest- ing synthetic product used in perfumery. It is made from citral and acetone and is marketed in the form of a 10% solu- tion. It is used as a substitute for oil of orris and its active principle irone. Ionarol is a very closely related prod- uct, and irone is also an article of com- merce. These substances are used for making violet perfume but alone they do not possess the requisite "body" and require fortification with violet pomade washings and oil of orris. Heliotropin or Piperonal is a crystal- line substance made from piperine, also by oxidation of safrol, which is con- tained in oils of sassafras and camphor. On account of not keeping well, it should be dissolved when fresh in alco- hol and the solution should be kept in a cool, as well as a dark, olace. It has the odor of heliotrope. (EUlet is a name applied to Artificial Carnation; it is chemically Isoeugenol, a derivative of eugenol. It is a thick- ish, yellow liquid, and is used for pre- paring carnation scent. Perfumes possessing the clover or treile odor have become very popular. These are made with Amyl Salicylate as a base, which is known commercially by such names as Trefol, Orchidol, and Trecarnol. Terpineol or Lilacine is prepared by the action of dilute sulfuric acid upon terpin hydrate. It appears in two forms, a liquid and a semi-solid, of which the former is the finer. It has the odor of lilacs and it also recalls the odor of elder flowers and hyacinths. It is fre- quently of poor quality. What is sold as Muguet or Oil of Muguet is terpineol mixed with smaller quantities of other ingredients. A synthetic of importance is Methyl Anthranilate, which is made by a secret process. It has an odor resembling oil of orange flowers but a real Artificial PERFUMES. 889 Oil of Neroli is also obtainable. The component parts are kept secret but probably consist of methyl anthranilate, geraniol, geranyl acetate, linalool, linalyl acetate, limonene, and indol. Bromelia and Yara are two similar compounds used in perfumery (mostly for soaps), the former being the ethyl ester, the latter the methyl ester, of betanaphthol. The former has an odor recalling cassie flowers, the latter the odor of orange blossoms. Artificial Oil of Jasmin is also a per- fect reproduction of the natural oil. In this case, as in that pf Neroli for Orange Blossoms, it was only necessary for the chemist to discover the com- ponent parts of the natural oil and then to combine these constituents (taken from other sources). For example, oil of jasmine was found to have the fol- lowing percentage composition : Benzyl acetate 65.5 Benzyl alcohol 6.0 Methyl anthranilate 0.5 Linalool 15. 5 Linalyl acetate 7-5 Jasmone 30 Indol 2.5 The chemist has only to make and mix these constituents in his laboratory to reproduce the pure oil. Practically this oil is said to be made from the following mixture : Benzyl acetate parts 55 Benzyl alcohol parts 20 Linalyl acetate parts 15 Linalool parts 10 The artificial oil is cheaper than the natural because of the scarcity of the flowers, and is also considered superior because it is always uniform and has not been altered by distillation or any process requiring heat. Ylang Ylang, produced artificially in the synthetic form, is considered supe- rior to the natural product because it is always uniform and much less expen- sive. What is called Oil of Niobe is chemi- cally Methyl Benzoate. It is described as a liquid of a pleasant odor. What has been sold as "artificial oil of lemon" was found to be merely an alcoholic solution of citral obtained from lemongrass oil, sometimes with a little real oil of lemon added to it. On account of the multiplicity of the newer perfume products it has been possible to exploit some fake substances and it behooves the manufacturer of perfumes to be on his guard in purchasing his supplies. What has been sold as "iri- sol" for the manufacture of violet per- fume was found to consist of 2^% of concrete oil of orris and 97^2% of acet- anilid. A number of other "fake" perfume products have been exposed, viz.: Ambrettaria was found to be a mix- ture of 1 part of musk-seed (ambrette) oil, 19 parts of acetanilid, with traces of artificial musk. Oil of Catalpa; terpineol with a little added oil of ylang ylang. Oil of Narcissus ; a by-product in the manufacture of terpineol. It was of- fered for making the scent of narcissus. Oil of Ylang Ylang was found to be cananga oil with a little added oil of Peru balsam. There are also synthetic substitutes for musk, civet and ambergris, which will be referred to later. ALCOHOL. A vehicle is required to hold the deli- cate floral oils and other odorous prin- ciples and none has proved more satis- factory than ethyl or grain alcohol. It volatilizes readily yet not too rapidly, it is a solvent of a wide range of power and is entirely unalterable or non-de- composable. Its slight odor is its only objection as the ideal vehicle for per- fumery purposes is entirely inodorous. It is sometimes impure, due to the pres- ence of fusel oil, furfurol and other odorous contaminations which would modify or destroy the delicate fragrant odors which are the main ingredients of fine perfumes. The best kind of alcohol is what is known as "deodorized alco- 890 THE STANDARD FORMULARY hol." Another grade of alcohol which is fairly good is what is sold as "cologne spirit," which is the "middle run" ob- tained in the manufacture of ordinary alcohol, and is fairly free from fusel oil. The difference between ordinary alco- hol and purified alcohol can be deter- mined very easily by rubbing a few drops between the hands and allowing the alcohol to evaporate entirely; a re- siduary odor remains in the case of or- dinary alcohol, which is quite marked and very pungent and objectionable. The alcohol should also be of full strength for perfumery purposes as a weak spirit will dissolve oils imperfectly. Many methods for deodorizing alco- hol have been recommended but the fol- lowing wiil be found satisfactory : A convenient amount of alcohol is shaken with powdered potassium per- manganate until it assumes a decided color. Then allow to stand for several hours until the permanganate has be- come decomposed, and brown manga- nese dioxid has deposited. A pinch of pulverized calcium carbonate should then be added and the whole subjected to distillation, using a well-cooled re- ceiver. Distil very slowly at first, test- ing the distillate frequently, until a mix- ture of the distillate and a strong (syrupy) solution of pure caustic soda or potassa, in the proportion of 10 of the former to I of the latter, gives no perceptible yellow coloration, on stand- ing for 20 minutes or half an hour. The first portion of distillate that yields this coloration should be rejected; the last one-eighth of liquid should not be distilled and should also be rejected. The remaining portion only is adapted for use. Another excellent means of deodor- izing is by adding I to i l /> drams of so- dium peroxid to a gallon of alcohol, al- lowing to stand 24 hours, agitating oc- casionally, and then carefully distilling. To avoid the dcodorization of alcohol with its consequent bother and loss by distillation, as well as to overcome or subdue its natural odor, it has been sug- gested to treat in other ways or to make various additions. The following have been suggested : I. Alcohol gall. I Quicklime, in powder dr. 4 Alum, powder dr. 2 Spirit of nitrous ether dr. 1 Mix all together, shake thoroughly, set aside for 7 days, agitating occasion- ally, and filter. II. Alcohol gall. 1 Animal charcoal .av.oz. 2 Spirit of nitrous ether m. 30 Oil of nutmeg m. 30 Cumarin gr. 20 Vanillin gr. 10 Tincture of Siam benzoin, .fl.oz. 1 Macerate the alcohol with charcoal for at least 7 days, agitating frequently, filter through talcum, and then add the other ingredients. The latter combination is said to blend and sweeten the odorous constit- uents of perfumes, and at the same time serves as a "fixing" agent. Slightly different is the following, which has also been highly recom- mended : Cumarin : gr. 5 Vanillin gr. 10 Spirit of nitrous ether fl.dr. 4 Tincture of benzoin fl.oz. 4 Glycerin fl.oz. 8 Alcohol gall. 1 Wood or methyl alcohol in a highly purified form has been suggested as a vehicle for perfumes but it has a stronger and more persistent odor than pure ethyl alcohol and its poisonous character renders it entirely unfit for this purpose. AROMATIC WATERS. Orange flower and rose waters are frequently employed in perfumes as a solvent or diluent. Only the best im- ported full-strength "triple" water should be used for fine handkerchief extracts. If plain water is required, distilled water only should be used. PERFUMES. 891 SOLID SUBSTANCES USED IN PERFUMERY. A number of interesting and impor- tant solid substances are used in making handkerchief perfumes, toilet waters, sachet powders and fumigating powders. The most important, interesting and valuable of these are the substances of animal origin, Musk, Ambergris and Ci- vet, which are used mainly in the man- ufacture of handkerchief perfumes. All three have an intense and repulsive odor but they are used generally not for their own odor but for their peculiar prop- erty of imparting persistency, i. e., "fix- ing" the fugitive flower-* odors and mak- ing them permanent. For this purpose only very small amounts are required. Owing to their expensive character and the difficulty of detecting impurities, they are subjected to the grossest adul- teration and the utmost care must be exercised to obtain the purest product. Musk is the most extensively em- ployed of the three animal substances mentioned. There are two principal va- rieties, the Tonquin, or so-called Thi- betan or Chinese, and the Russian or Siberian. It comes into the market in two forms, pods and "grain," both of which are adulterated sadly and in di- verse ways. The first form is the pods as they are removed from the animal, the musk deer, but it is not practicable for ordinary dealers to buy this form. It is frequently adulterated with lead or pieces of stone to increase the weight. "Grain musk" is the dried secretion of ther musk sac in a granular form, whence the name. It is adulterated with pieces of dried liver, dung and other animal matter, and sometimes it con- sists almost entirely of foreign animal matter with a little musk added to im- part an odor. It may be obtained at any price according to the degree of adul- teration. It should be purchased from responsible dealers who are willing to furnish a guaranty. The odor of musk is subdued or mod- ified by camphor, acids, various essen- tial oils, etc., and is intensified by small amounts of alkali. There are other sub- stances which have a musk-like odor such as the secretion of the musk rat, also musk (or sumbul) root and musk seed. The latter is used in perfumery and will be referred to later ; musk root is employed only for medicinal pur- poses, and the musk rat secretion has been experimented with for perfumery purposes but has never gained favor. Ambergris, so-called from its fancied resemblance to amber, is a disease ex- cretory product derived from the intes- tines of the sperm whale. It is found floating on the surface of the ocean. Civet is a secretion derived from the civet cat, an animal found in North Af- rica and East India. It is obtained mostly from India, where the animal is kept in captivity to obtain this secre- tion. All three animal substances yield their virtues to alcohol. To facilitate extrac- tion they should be first triturated with at least an equal amount of finely granu- lated orris root. Musk, ambergris and civet are now frequently replaced by synthetic prod- ucts called Artificial Musk, Ambrol and Artificial Civet (or Civetol), but which are not artificial products in the sense that artificial oils of jasmine and ylang yland are exact substitutes for the nat- ural oils, but are synthetic chemicals having an odor similar to the natural products. Artificial Musk, also called Musc- Baur and Tonquinol, is chemically, trini- trobutyl-xylene. It is in white or yel- lowish crystals which are soluble in al- cohol and have a strong musk-like odor. This is sometimes replaced or substitut- ed by inferior substances. Musk Seed, also called abelmoschus or ambrette seed, is derived from a plant grown in Egypt and India. It has an appearance similar to flaxseed and is of a strong musk-like odor. It is used in 892 THE STANDARD FORMULARY the form of an alcoholic tincture. An oil, called Oil of Ambrette, is obtained from it by distillation. A number of resinous substances are used in perfumery such as benzoin, storax, myrrh, tolu, and Peru balsam. Only the best kinds should of course be employed. Benzoin and myrrh should be used in the whole form, which is to be reduced to coarse powder as re- quired; the commercial fine powder is unfit for any purpose whatever. The variety of benzoin known as Siam is the kind that should receive preference. In handkerchief perfumes and toilet waters these resinous substances are used in the form of alcoholic tinctures. In the dry form they are used in sachet powders and other solid perfumes. Orris Root is a very important sub- stance used in perfumery products. There are two principal kinds, Floren- tine and Verona, the former being pre- ferred. It is generally employed in the granulated form or about No. 40 pow- der for sachet powders, which form is also suitable for making tinctures to use in handkerchief perfumes and toilet powders. Tonka and vanilla beans are also used in perfumes in the form of a tincture. As usual, only the best kinds should be employed. Other solid substances, such as lavender flowers, cloves, orange peel, etc., are used mostly in making sachet powders and will be referred to under this latter heading. COLORS FOR PERFUMERY. In perfumes the appearance next to the odor plays an important part, and hence it is essential to tint this class of articles properly. Any accidental color present is an obstacle as it would cause stains on the fabrics upon which they are used. Hence the aim is to obtain perfumes either colorless or at the most of a very pale tint, pale green, for exam- ple, being common, the latter being of such a character that it disappears on drying. Essence of cassie and violet possess this color and in many cases one of these essences is added to perfumes with the view of imparting this desirable color. Sometimes a small amount of an aniline dye is used, but this may be ob- jectionable either because of leaving a stain on the fabric or because of fading out on exposure of the perfume to light. The most usually employed green color is chlorophyll, using the so-called alco- hol-soluble kind. Very little of this is required and it is resistant to light. A mixture of potassium chromate and cop- per sulfate is said to make a satisfactory tint which is very resistant to light. An acceptable green coloring agent for w T hite rose extract is a tincture of pat- chouly made in the proportion of 1 part of the leaves to 4 parts of alcohol. Most perfume mixtures are of a pale brownish tint, especially if they contain resinous bodies like benzoin, storax and Peru balsam, but if a somewhat darker brown shade is demanded it may be im- parted by means of rhatany root or the tincture. Red saunders gives a reddish brown color. A red color may be imparted by means of carmine in solution, using the solu- tion of carmine of the National For- mulary. Only a very small amount is required. Or use Cochineal Color of the N. F. or a hydroalcoholic tincture of cochineal. A yellow color may be imparted by means of saffron or curcuma, only small amounts being required. Essence of jonquille also imparts a yellow tint and may be added to perfume mixtures to obtain this shade. As stated, however, the perfume is commonly allowed to retain its natural color which is usually a pale brown or it is colored greenish, and only very small amounts of tinting material should be used to avoid staining the handkerchief or dress upon which the perfume is used. PERFUMES. 893 COMPOSING OF PERFUMES. Despite the manufacture of the num erous modern perfume products of the chemist's laboratory, the natural odors of the flower garden are still the requi- sites in the making of fine perfumes. The eight fundamental odors, accord- ing to an authority, are Rose, Violet, Tuberose, Jasmine, Cassie, Migonette, Jonquille and Orange Flowers. This does not exhaust the list of flower odors nor does it take account of other natural odors derived from leaves, roots, woods, etc., nor of those synthetic odors which are not imitative of flower odors. With these basic odors it is claimed to be possible to produce the long list of standard perfumes by varying the pro- portions and adding other modifying in- gredients, the necessary balsamic, fruit or spice odors, to impart the individual characteristics. These basic odors con- sist either of pomade washings or of essential oils, or possibly of both, but they are now frequently replaced, in part only as a rule, by the corresponding synthetic compounds or mixtures. The synthetic perfume products have the fault of "thinness," that is, are lacking in "body," so that it is impossible to use them alone in building up or composing a fine perfume. It seems a singular fact that it is im- possible to produce satisfactory flower odors by simply extracting the flowers themselves. The pomade washings or essential oils derived from these flowers are, like the synthetic perfumes, lacking in "body" and need fortification. The natural prod- ucts and the synthetics are now usually employed in conjunction, each one im- parting strength and stability to the other. Flower odors like the rose and violet are made from the oils or pomade wash- ings of these flowers but there are other flowers, such as lilac, crabapple, and heliotrope, of which there are no corre- spending oils or pomade washings and the odors must be made or imitated by mixing various oils, pomade washings and synthetics. Very excellent imita- tions indeed have been worked up by skillful perfumers. There are also many perfumes man- ufactured which have no counterpart in the flower garden, orchard or spice grove, but are nevertheless pleasing combinations and have achieved great popularity. Such are Jockey Club, Mille- fleurs, Frangipanni, Mousseline, "Ocean Spray," "Upper Ten," "West End," etc. These mixtures are in perfumers' parl- ance designated as "bouquets." Many of the most popular and expensive per- fumes of the present time are bouquet odors. It would not be possible to make the vast array of these new and exqui- site creations without the numerous syn- thetic perfume products. A really elegant perfume should have the properties of agreeability, intensity and persistency. Agreeability is secured by judicious combination of ingredients, such as mix- ing substances that fortify each other or that are complementary to each other, or modifying excessively sweet odors with aromatics, or toning down aromatic odors with sweet ones. Intensity is secured by not adding too great a proportion of the vehicles, alco- hol and water, also by fortification of the "weaker" or "thinner" odors with stronger ones. Persistency is usually imparted by adding small amounts of certain sub- stances of a strong odor, known as fixa- teurs or "fixing agents" which hold or "fix" the perfume when exposed on a handkerchief. Intensity is secured by about the same agents as impart per- sistency, musk and civet among animal substances, artificial musk among syn- thetics, and oils of patchouli and santal and balsamic tinctures among vegetable products. A satisfactory rose perfume, for ex- ample, cannot be obtained by dissolving 804 THE STANDARD FORMULARY oil of rose in alcohol or by washing rose pomade. The perfume would lack intensity and persistency; fortification with other agents is necessary to secure these, and these agents, judiciously se- lected and sparingly added, modify the odor so as to produce the different shades of rose odor which are so famil- iar to us. In the case of artificial odors, or "bouquets," an agreeable perfume is made by blending the constituents in such a manner that no special odor is recognized. There should be sweetness and agreeability but not oppressiveness. The following table is an interesting one as showing the relationship between the different odors : weeks at least) to allow it to "ripen" or blend, after which it may be filtered. If the ingredients of handkerchief ex- tracts be classified according to their function, the classification would be as follows: (i) Odorous agents; (2) fix- ing agents, and (3) vehicle. The essential odorous agents are the essences, spirits or oils, and chemical substances. The "fixing" agents consist of the musk, ambergris, civet, resins, orris, oils of ylang ylang and patchouli, etc. The distinction between the first and second classes is not sharply drawn, for the reason that some of the "fixing" agents are used for their odor as well as for their "fixing" properties. The third Classification of Odors. Classes. Types. Odors Belonging to the Same Class. Rose Rose Geranium, sweet brier, rosewood. Jasmine Jasmine Lily of the valley, white pond lily, ylang ylang. Orange flower . . Orange flower . . Cassie, syringa, orange leaves. Tuberose Tuberose Lily, jonquille hyacinth. Violet Violet Orris root, mignonette. Balsamic Benzoin Balsam of Peru, tolu, benzoin, storax. Vanilla Vanilla Tonka. Spice Cinnamon Nutmeg, mace, pimento. Clove Clove Carnation, clove pink. Camphor Camphor Rosemary, patchouly. Sandal Sandalwood Vetivert, cedarwood. Citrine Lemon Bergamot, orange, cedrat, limette. Herbaceous Lavender Thyme, marjoram, wild thyme. Mint Peppermint Spearmint, balm, rue, sage. Anise Aniseed Caraway, dill, coriander, fennel, star anise. Almond Bitter almond . . Peach kernels, cherry-laurel. Musk Musk Civet, musk-seed, sumbul, ambergris. Fruit Pear Apple, pineapple, quince. HANDKERCHIEF EXTRACTS. (General Remarks.) Handkerchief extracts, or "extracts," as they are more commonly termed, are produced by incorporating with alcohol one or more essences (see definition of term below), one or more spirits (alco- holic solutions of volatile oil) or possi- bly the oils themselves, and a tincture of some of the animal or resinous sub- stances mentioned above. Most gener- ally now other ingredients are added, such as one of the synthetic perfumes, which really takes the place of the vola- tile oil or spirit. This mixture should be set aside for some time (several class practically embraces but one sub- stance, viz., alcohol, although rose and orange flower water are someties added after the alcohol, and may therefore also be considered as vehicles. The office of "fixing" agents is chiefly to hold the perfume to, or fix, or fasten it upon, the handkerchief or other fabric to which it is applied, it being understood that the odoriferous mat- ters all being very volatile and exceed- ingly evanescent when exposed to ^the atmosphere. The "fixing" agents also serve to hold or secure the delicate flower odors to the vehicle while the mixture is still present in the container as "extract." These substances there- PERFUMES. 89! fore allow the perfume to be exhaled or emitted very slowly, in this wise resem- bling the exhalation of the odor from flowers. The "fixing" agents are of five va- rieties, as follows : 1. Fatty matter derived from pomades during- extraction with alcohol. 2. Resinous substances, such as Peru balsam, tolu, storax, benzoin, orris, musk-seed, etc., and even myrrh, asa- fetida, etc., have been employed. 3. Volatile oils of the type like oils of sandalwood, patchouli, ylang ylang, and vetivert. 4. Animal substances, which include musk, ambergris, and civet. 5. Synthetics, viz., artificial musk and artificial civet. The objection to the first class is that it soon decomposes and imparts a rancid odor to the perfume, hence pains are taken to exclude rather than to retain it. How this may be done is described ander the heading of Essences. Milk has been suggested as a "fixing" agent. When used it is to be added, preferably first warmed, in the propor- tion of 1 ounce to a gallon of handker- chief extract. Smaller amounts of milk would be needed when used for weaker perfumes. The butter fat is the con- stituent of milk that acts as the fixa- tive. The objection to the resinous class is but an aesthetic one and hence is less serious than in the preceding. The resins impart a high color to the per- fume and when the latter is dropped on a white handkerchief the fabric at once presents a soiled appearance. This is one reason why benzoin is often re- placed by benzoic acid obtained by sub- limation of the resin. Orris does not have the objection of imparting a high color, but the amount of resinous mat- ter is so small that a very concentrated alcoholic tincture must be employed. Of course, all resins are objectionable because of their own odor, which may perceptibly modify the other odors, and this is sufficient reason why different resins are selected for different per- fumes. The volatile oils used as fixing agents are of the kind having a "heavy," in- stead of a sweet or aromatic odor. They are used in small amounts only. The animal class of "fixing" agents is remarkable in that but trifling amounts will serve the purpose, and hence they are the most largely employed. The one objection to their use is their pro- nounced and very persistent odor, which is likely to remain after the other odor- ous substances have dissipated. The most modern "fixing" agents are of course artificial musk and arti- ficial civet, the former being quite largely used. These substances have the advantage of being colorless, en- tirely soluble and of uniform compo- sition. A convenient and popular, though in- definite, classification of "extracts" is into "delicate odors" and "heavy odors," the former including such as violet, heliotrope, lilac, etc., the latter musk, jockey club, etc. PRESERVATION OF PERFUMES. All perfumes, but particularly the "ex- tracts," containing, as they do, readily decomposable essential oils, should be properly cared for if they are to retain their pristine freshness of odor and of color. The most damaging agent is light, especially strong sunlight, caus- ing some colors to fade, others to dark- en, and modifying or destroying odors. The stock of perfumery should there- fore be displayed rather at the rear half of the store instead of in front where the sun's rays may have ready access to it. Owing to the deleterious effects of strong light, manufacturing perfumers use large labels on their bot- tles and some even go so far as to have a closely adherent wrapper for the bot- tle, the label being on the outside of this^ wrapper. The room for the storing and the location of the display of perfumes 896 THE STANDARD FORMULARY should be of a moderate and also of a fairly even temperature, not subject at least to extremes of cold and heat. The former is liable to cause temporary separation of essential oils and other ingredients, from the alcoholic solution, the latter hastens oxidation and pro- duces permanent injury. This is another reason for displaying perfumes away from the front part of the store where the heat of the sun's rays may reach them. Locations near heaters or regis- ters should also be avoided. Excessive exposure - to air is also prejudicial to perfumes. For this rea- son, they should be displayed in bottles no larger than 8 ounce which should be well-stoppered, preferably with a glass stopper. It may even be advisable to have a number of small bottles in a display rack to avoid using the larger bottles except in cases of a sale. Resinous and oily portions of per- fumes prone to collect on the lips of the bottles and on adjacent portions of the stoppers, and these portions oxidize through contact with the air, and in this wise, patrons may get an erroneous impression of the odor. The lips and stoppers of bottles should therefore be cleaned frequently, wiping with a little alcohol on a cloth if necessary. DISPLAYING OF PERFUMES. From what has been stated in previous paragraphs it may be gathered that in choosing a location in- the store for the effective display of perfumes, more than appearance must be had in mind. While the goods should be effectively and tastily displayed, they should not be subjected to excessive light nor to extremes of temperature. The number of odors carried in stock should not be too great but of course sufficiently varied to suit all tastes. Sometimes it may be necessary to carry cheaper as well as higher-priced odors of the same kind to meet the limitations of some purses. A common practice in showing these goods to prospective customers is to re- move the stopper from the stock bot- tle, and allow the customer to smell di- rectly from the latter. The vehicle al- cohol being more volatile than the oils and other ingredients which form the real perfume, obtrudes itself upon th? olfactory nerves and crowds away, as it were, the more delicate odors. The proper method of showing the "ex- tracts" and indicating the differences between them is to wet the stopper by inverting the bottle, then to moisten a strip of blotting paper or a piece of rice (cigarette) paper, allowing the lat- ter to become almost dry before handing to the patron. Another good suggestion is to have a small sample rack of perfumes con- taining a number of glass-stoppered half or one ounce bottles; this will enable the pharmacist to keep the stock bottles in a dark place to be opened only when an "extract" is to be dispensed. The sample rack may also be kept in a dark place when not in use. If the glass stop- pers of the bottles of the rack are of the elongated kind, so as to reach to the bottom of the bottle, the tissue or rice paper may be dispensed with. In showing "extracts," for purposes of sale, the order in which they are shown is also a matter of consequence, especially when the prospective customer does not have any preferences. The finest, most delicate odors should always be shown first ; if the heavy odors be presented first, the olfactory nerves will have become so impressed with the lat- ter that the delicate odors which are shown subsequently will appear to be decidedly lacking in quality, and thus a sale may be lost. The sale of "mixed odors," that is, a mixture of two or more "extracts," should be discouraged because each "ex- tract" is a harmonized blending of odors, and mixing "extracts" is liable to de- stroy this harmony. However, this mat- PERFUMES. 89' ter may not be of such great conse- quence, because those that ask for "mixed odors" do not properly appre- ciate the value of a well-made "ex- tract." ESSENCES. Essences (extracts, extraits and es- prits, they are also termed) are pre- pared, as already stated, by extraction of the odorous substances from pomades by means of alcohol, this process be- ing known generally as "washing." The best method of washing is as follows : Sixteen av. ounces of the pomade, us- ing a No. 24 or 30, are cut into small pieces and placed in a bottle of sufficient capacity, such as a fruit jar, in which is put 16 fluidounces of pure alcohol. Place the bottle, suitably stoppered, in a water bath, and apply heat sufficient to barely melt the pomade, shake well together, and repeat the shaking fre- quently until the fatty matter solidifies. In this way the pomade will be reduced to a finely divided or granular state, permeated thoroughly by the alcohol. Allow this to stand for a week — a month or even longer would be better — giv- ing it an occasional shake, then drain off the liquid into another bottle ; if this fall short of 16 fluidounces, repeat the operation with a sufficient quantity of alcohol to make up to this measure. To remove the fatty matter this liquid should be placed on ice till well chilled after which it is strained. By subsequent and similar treatment, a second and even a third quantitv of essence may be made, which, although much weaker, will be found useful in the preparation of colognes and toilet waters. Some operators use the third essence for washing a new quantity of original pomade, thus making a stronger essence or enabling one to use a weaker pomade. The residual pomade may be utilized for making hair pomades or as a diluent for ointments, or for mak- ing fine soaps (by manufacturers). Essences prepared by the above method contain some fatty matter and . will soon become rancid. This retained fatty matter can be separated by the ap- plication of cold, and in order that it may be adopted in preference to the pre- ceding one: Into an ice cream freezer of a size commensurate with the quan- tity of essence to be prepared, pour the requisite quantity of alcohol, then heat the pomade cautiously upon a water bath until melted, pour this into the freezer, put on the cover, set the apparatus in motion and continue the heating for 15 or 20 minutes, by which time probably all the odorous matter will have been extracted. Now sur- round the can with a freezing mixture, composed of ground rock salt and cracked ice, resume the beating until the liquid is thoroughly chilled and the fat has all adhered to the paddle and the sides of the can. Then open the freezer, pour off the liquid, and pass through a well-covered filter to separate the particles of fat still suspended in the liquid. As already stated, the essence used are rose, jonquille, cassie, reseda, jas- mine, violet, tuberose, and orange flower. Formerly the washings of the pomades of these flowers were considered in- dispensable for the making of fine per- fumes, but at the present time the prac- tical manufacturer is quite likely to replace them with alcoholic solutions of the concrete oils. The full strength oils must be used, not any dilutions with wax or solutions in alcohol. The proportions used are one ounce of oil to one gallon of alco- hol. The oil should be first triturated with a small amount of alcohol, to break up the lumps then the remainder of the alcohol added, the whole set aside for 24 hours, during which it should be frequently agitated, and finally fil- tered. This has about the same strength as a first pomade washing and may be used in place of the latter. The resi- due on the filter may, like the pomades, be subjected to a second and even a third washing. 898 THE STANDARD FORMULARY The advantage of using these oil solu- tions are many. The pomade washings can never be entirely freed from fatty matter and there is a great deal of tedi- ous manipulation to thoroughly extract the pomade, as well as considerable loss of alcohol during manipulation. SPIRITS. The formula here given are for those spirits which are used in the making of perfumes mentioned in this work. Only the very best quality of oil should be used and only the best obtainable al- cohol. A full description of the oils will he found under the heading Essential Oils. It is said that the longer these spirits are allowed to stand, i. e., the older they are, the better they are adapt- ed for perfumery purposes. Spirit of Almond. Oil of bitter almond m. 80 Alcohol fl.oz. 16 Spirit of Ambrette. Oil of ambrette fl.dr. 2 Alcohol fl.oz. 8 Spirit of Bergamot. Oil of bergamot fl.oz. 1 Alcohol fl.oz. 15 Spirit of Cedarwood. Oil of cedar (Lebanon) fl.dr. 4 Alcohol fl.oz. g l / 2 Spirit of Cinnamon. Make from 1 fluidounce of oil of cinnamon (Ceylon) and 9 fluidounces of aicohol. Spirit of Clove. Oil of clove, Bourbon fl.dr. 4 Alcohol fl.oz. i$ l / 2 Spirit of Hyacinth. I [yacinthin gr. 60 Alcohol fl.oz. 16 Spirit of Lavender. Prepare from 1 fluidounce of oil of lavender flowers and 19 fluidounces of alcohol, using the Mitcham oil of lav- ender. Spirit of Lemon. Prepare from 1 fluidounce of oil of lemon and 19 fluidounces of alcohol. Spirit of Lemon-Grass. Oil of lemon-grass fl.oz. 1 Alcohol fl.oz. 15 Spirit of Linaloe. Oil of linaloe fl.dr. \% Alcohol fl.oz. 8 Spirit of Lilac. Terplneol or lilacin dr. 2 Alcohol fl.oz. 8 Spirit of Neroli. Oil of neroli petale fl.dr. 4 Alcohol fl.oz. 15^ Artificial oil of neroli may be sub- stituted for the natural oil. Spirit of Nutmeg. Make from 1 fluidounce of oil of nutmeg and 19 fluidounces of alcohol. Spirit of Orange. Prepare 1 fluidounce of oil of orange and 19 fluidounces of alcohol. As stated in the introductory remarks on perfumes, the oil of bitter orange peel is to be preferred. Spirit of Orris. Oil of orris, liquid fl.dr. 1 Alcohol fl.oz. 8 Spirit of Patchouly. Oil of patchouly fl.dr. 4 Alcohol fl.oz. is l A Spirit of Pimento. Oil of pimento fl.oz. 1 Alcohol fl.oz. 15 Spirit of Rose. Oil of rose fl.dr. 4 Alcohol fl.oz. 7l/ 2 Artificial oil of rose may be used instead of the natural oil. Spirit of Rose, Compound. Spirit of rose fl.oz. 2 Spirit of rose geranium fl.oz. 2 Alcohol fl.oz. 4 Or mix Oil of rose fl.dr. 2 Oil of rose geranium fl.dr. 1 Alcohol, to make fl.oz. 16 The oil of rose geranium is added to give permanence to the spirit. Spirit of Rose Geranium. Oil of rose geranium fl.dr. 4 Alcohol fl.oz. 15K PERFUMES. 899 Spirit of Sandal. Oil of sandalwood, East India fl.dr. 2 ' Alcohol, to make fl.oz. 16 Spirit of Vetivert. Oil of vetivert fl.dr. 1 Alcohol fl.oz. 8 Spirit of Ylang Ylang. Oil of ylang ylang fl.dr. 3 Alcohol fl.oz. 16 The artificial oil may be used instead of the natural. TINCTURES. The formulas here given are for the tinctures used in making the perfumes mentioned in this work. It is said that the older these tinctures are, the better they the adapted for making per- fumes. Tincture of Ambergris. Ambergris dr. 2 Orris root, powder dr. 2 Alcohol fl.oz. 16 Rub the ambergris and orris in a mortar, until reduced to a fine powder ; transfer to a bottle, and add the alcohol. Macerate for 30 days, agitating occa- sionally, and filter through paper. Tincture of Ambrette. Musk seed av.oz. 4 Alcohol sufficient Reduce the drug to fine powder, and extract by slow percolation so as to ob- tain 16 fluidounces of product. Tincture of Siam Benzoin. Siam benzoin, fine powder. av.oz. 2 Alcohol fl.oz. 16 Mix, macerate for 7 days, agitating occasionally, and filter. Tincture of Civet. Civet dr. 1 Orris root, powder dr. 1 Alcohol fl.oz. 16 Proceed as with tincture of ambergris. Tincture of Artificial Civet. Artificial civet..- av.oz. 1 Alcohol, to make fl.oz. 16 Mix, dissolve and filter. Tincture of Musk. Musk, grain dr. 2 - Orris root, granular dr. 2 Lime water fl.oz. 4 Alcohol fl.oz. 12 57 Rub the musk thoroughly with the orris, then with the lime water, previ ously warmed, macerate in a covered mortar . for 2 hours, add the alcohol, transfer to a bottle, cork tightly, mac- erate for 30 days or longer, preferably in a rather warm place, agitate fre- quently, and finally filter. Tincture of Artificial Musk. Artificial musk dr. 2 Alcohol fl.oz. 16 Mix and dissolve. Tincture of Orris, Stronger. Orris root, powder av.oz. 8 Alcohol sufficient Extract the drug by slow percolation so as to obtain 16 fluidounces of product. Tincture of Orris, Weaker. Orris root, powder gr. 600 Alcohol, to make fl.oz. 16 Prepare like the preceding. Tincture of Storax. Storax av.oz. 1 Alcohol, to make fl.oz. 16 Mix, macerate for 14 days with occa- sional agitation, and filter. Tincture of Tolu. Prepare from 1% av. ounces of tolu and enough alcohol to make 16 fluid- ounces. Tincture of Tonka. Tonka av.oz. 3 Alcohol sufficient Reduce the bean to moderately fine powder, add 16 fluidounces of alcohol, macerate ■ for 14 days, agitating occa- sionally ; filter, and add enough alco- hol through the filter to make 16 fluid- ounces of product. Tincture of Vanilla. Vanilla gr. 480 Sugar (granulated or rock candy) gr. 480 Alcohol fl.oz. 16 Cut the drug into small pieces, beat with the sugar in a mortar until reduced to coarse powder, macerate with the alcohol for 30 days, and filter. 900 THE STANDARD FORMULARY HANDKERCHIEF EXTRACTS (Formulas). It is quite essential that the amateur manufacturer of "extracts" very care- fully peruse the preceding pages to in- form himself upon the varieties of ma- terials used in perfumes, the method of preservation, etc. It may be stated that the "extracts" can be cheapened by the use of weaker pomades or inferior oils, or of a tinc- ture of musk of one-half the strength given, by the substitution of civet for the ambergris, by the addition of larger proportions of alcohol and of some wa- ter, etc. Acacia Extract. Essence of cassie fl.oz. 4 Stronger tincture of orris, .fl.oz. 2 Tincture of vanilla fl.dr. 12 Tincture of ambergris fl.dr. 4 Alcohol fl.oz. Sy 2 Alisma Extract. Essence of rose fl.oz. 3^2 Essence of jasmine fl.oz. 3^ Essence of violet.. fl.oz. s l / 2 Essence of jonquille fl.oz. 3 x / 2 Tincture of ambergris fl.oz. 1 Tincture of musk fl.oz. 1 Ambergris Extract. Compound spirit of rose. . .fl.oz. 3 Tincture of ambergris fl.oz. 8 Tincture of musk.... fl.oz. 4 Tincture of vanilla fl.oz. 1 Azalea Extract. Vanillin dr. 3 Heliotropin m. 25 Oil of neroli, synthetic m. 25 Tincture of musk fl.oz. 1 Essence of rose fl.oz. 10 Essence of violet fl.oz. 10 Essence of tuberose ...fl.oz. 10 Gum benzoin, Siam av.oz. 2 Alcohol fl.oz. 4 Mix, macerate for a week or two, agitating frequently, and filter. The benzoin should be freshly pow- dered. Cherry Blossom Extract. Aubepine drops 3 to 10 Anethol drops 1 Oil of bitter almond m. 15 Oil of fennel m. 15 Oil of bergamot m. 15 Oil of neroli m. 75 Acetic ether m. 45 Vanillin gr. 30 Cumarin gr. 5 Tincture of musk fl.dr. 6 Tincture of Siam benzoin, .fl.oz. 2j4 Tincture of orris, stronger, .fl.oz. 8 Essence of rose (3rd wash- ing) fl.oz. 15 Alcohol fl.oz. 4 Clove Pink Extract. Essence of rose fl.oz. 6 Essence of cassie fl.oz. 4 Essence of orange flowers, .fl.oz. 4 Tincture of vanilla...-. fl.oz. 2 Oil of clove, Bourbon drops 10 Clover (Japan) Extract. Essence of cassie fl.oz. 10 Spirit of rose fl.oz. 4 Tincture of musk fl.oz. 3^ Tincture of artificial musk.. fl.oz. 4 Solution of ionone, 10% fl.dr. 3 Oil of bergamot fl.dr. 2 Oil of petitgrain fl.dr. 1 Oil of clove fl.dr. 1 Cumarin gr. 20 Alcohol fl.oz. 13 Cosmos Bouquet Extract. Essence of jasmine fl.dr. 6 Oil of bergamot fl.dr. 3 Oil of lemon .drops 15 Oil of lavender, Mitcham. .drops 9 Oil of clove, Bourbon drops 3 Cumarin gr. 3 Heliotropin gr. l / 2 Tincture of civet fl.dr. i l / 2 Weaker tincture of orris. . .fl.oz. 15 Mix and dissolve. Crab-Apple Flowers Extract. Essence of violet ..fl.oz. 4 Essence of rose ..fl.oz. 2 Essence of jasmine ..fl.oz. 1 Essence of cassie ..fl.oz. 1 Spirit of ylang ylang ..fl.dr. 6/ 2 Spirit of linaloe ..fl.oz. iV 2 Spirit of neroli ..fl.dr. 2V2 Compound spirit of rose ..fl.dr. 4 Spirit of hyacinth ..fl.dr. 2 Tincture of musk ..fl.dr. I Oil of mace, volatile .drops 4 Alcohol ..fl.oz. I Essence of jasmine, washing, to make. second fl.oz. 16 II. Oil of rosewood m. Oil of ylang ylang m. Oil of sandalwood m. Amyl acetate m. Apple ether fl.oz. 30 7o 100 20 I PERFUMES. 901 Essence of rose Essence of cassie Essence of jasmine... ...fl.oz. 4 ...fl.oz. • 6 . . . fl.OZ. 20 fl.oz. fl.oz. fl.oz. fl.oz. fl.dr. m. 8o fl.dr. i drops 5 fl.oz. \y 2 III. Essence of jasmine Essence of violet. . . Essence of tuberose Spirit of rose Tincture of civet.. Tincture of musk. Oil of ylang ylang. Oil of neroli Alcohol The oils may be the natural or the synthetic. Cupid's Kiss Extract. Essence of orange flowers, .fl.oz. 4^2 Essence of tuberose fl.oz. 4^2 Spirit of rose fl.oz. 3V 2 Tincture of civet fl.oz. 1 Tincture of musk fl.dr. 4. Spirit of ylang: ylang fl.dr. 2 Cumarin gr. 6 Vanillin gr. 3 Alcohol fl.oz. 2 Egyptian Lotus Extract. Essence of jasmine fl.oz. z% Essence of rose fl.dr. 3 Tincture of vanilla fl.oz. 2 Tincture of civet fl.oz. 2 T / 2 Tincture of Siam benzoin. ..fl.dr. 5 Spirit of neroli fl.dr. 7 Spirit of clove fl.dr. s x A Spirit of patchouly. fl.dr. 1 Oil o-f rose drop 1 Alcohol fl.oz. 6 l / 2 Elder Elower Extract. Essence of jasmine fl.oz. 2 Essence of rose fl.oz. 2 Essence of tuberose fl.oz. 2 Essence of jonquille fl.oz. 2 Essence of orange flowers, .fl.oz. 2 Spirit of ylang ylang fl.oz. 5 Tincture of musk fl.dr. 4 Tincture of ambergris fl.dr. 2 Terpineol gr. 60 Mix and dissolve. Essence Bouquet Extract. I. Compound spirit of rose fl.oz. 8 Spirit of lemon fl.oz. 2Y2 Spirit of bergamot fl.oz. 1 Spirit of neroli fl.oz. 1 Tincture of ambergris fl.oz. 1 Stronger tincture of orris fl.oz. 1 Essence of cassie fl.oz. 1 Alcohol fl-dr. 4 II. Essence of rose .fl.oz. 8 Tincture of orris fl.oz. 4 Tincture of musk fl.oz. 1 Oil of rose m. 15 Oil of neroli m. 15 Oil of bergamot fl.dr. 4 Oil of lemon fl.dr. 2 Rose water sufficient As much of the latter may be added as is possible without causing precipi- tation. 4 4 15 15 15 15 2 2 24 III. Vanillin gr Nerolin gr Oil of cedarwood m Oil of rosemary m Oil of clove m Oil of lavender flowers m Oil of lemon fl.dr Oil of bergamot fl.dr Alcohol fl.oz Mix, allow to stand for 6 days, agitat- ing frequently, and filter. It may be diluted with 18 fluidounces of distilled water. It is said to make a good but cheap perfume. Esterhazy Bouquet Extract. Essence of orange flowers, .fl.dr. 2^ 2 1 3 3 4 2 3 l A 2 1 2 5 Spirit of vetivert ....fl.oz. Spirit of rose ...fl.dr. Spirit of rose geranium. ...fl.dr. Spirit of neroli ...fl.dr. Spirit of sandal ...fl.dr. Spirit of clove ...fl.dr. Tincture of tonka ...fl.oz. Tincture of vanilla ...fl.oz. Stronger tincture of orris ..fl.oz. Tincture of ambergris... ...fl.dr. Alcohol ...fl.oz. Evening Primrose Extract. Essence of orange flowers, .fl.oz. Essence of rose Essence of jasmine Compound spirit of rose. Spirit of rose geranium. . Spirit of ambrette Spirit of patchouly Tincture of Siam benzoin Tincture of musk .fl.oz. .fl.oz. .fl.oz. .fl.dr. .fl.dr. . . . m. .fl.dr. .fl.dr. 3 2 2 5 10 4 80 4 1 [2 Alcohol fl.dr. Fashion Bouquet Extract. Oil of neroli m. 30 Oil of rose m. 45 Spirit of bergamot ....fl.oz. 1 Stronger tincture of orris.. fl.oz. 1 Tincture of musk fl.oz. 6 002 THE STANDARD FORMULARY Essence of jasmine fl.oz. 8 Benzoic acid, sublimed gr. 30 Alcohol, to make fl.oz. 16 Fleur de Lys Extract. Essence of tuberose fl.oz. 7 Essence of rose fl.oz. 2 Essence of violet fl.oz. 2 Essence of orange flowers, .fl.oz. I Essence of jasmine fl.oz. 1 Tincture of vanilla fl.oz. 2 Tincture of civet fl.oz. 1 Floral Jewel Extract. ..fl.oz. zVz ..fl.oz. 9 ..fl.oz. 9 ..fl.oz. 1 ..fl.dr. 4 ..fl.dr. 2 Spirit of rose Essence of tuberose. . Essence of violet. . . . Tincture of musk. . . . Oil of bergamot Oil of cedrat Oil of neroli portugal fl.dr. 2 Heliotropin gr. 30 Alcohol fl.oz. S l A Florida Lotus Extract. Essence of tuberose fl.oz. 6 Essence of jasmine fl.oz. 3 Essence of rose fl.oz. 2 Essence of cassie fl.oz. 2 Essence of orange flowers, .fl.oz. 1 Tincture of civet fl.oz. 1 Oil of linaloe m. 45 Oil of vlang ylang m. 30 Vanillin gr. 12 Heliotropin gr. 5 Alcohol fl.oz. 1 Flowers of Ireland Extract (Flowers of Erin). White rose extract fl.oz. 15 Tincture of vanilla fl.dr. 12 Flower of Seville Extract. Essence of jasmine fl.oz. 3 Essence of rose fl.oz. 3 Essence of violet fl.oz. 3 Essence of orange flowers, .fl.oz. 3 Tincture of musk fl.dr. 4 Tincture of ambergris fl.dr. 3 Vanillin gr. 10 Alcohol fl.oz. V/2. Forget-Me-Not Extract. Essence of jasmine fl.oz. 12 Essence of rose fl.oz. 8 Essence of violet fl.oz. 4 Essence of cassie fl.oz. 3 Tincture of civet fl.oz. 2 Tincture of musk fl.dr. 6 Oil of rose, natural or synthetic fl.dr. I Oil of bergamot m. 30 Oil of cedarwood m. 30 II. Frangipanni Extract. Essence of orange flowers, .fl.oz. 2^2 Spirit of sandal fl.oz. 4 Spirit of neroli fl.oz. 2 Spirit of rose fl.oz. 1 Tincture of musk fl.dr. 3 Tincture of tonka fl.dr. 11 Alcohol fl.oz. 3 l / 2 Tincture of musk fl.oz. 5 Tincture of civet fl.dr. 4 Stronger tincture of orris. . .fl.oz. 3 Essence of orange flowers, .fl.oz. 3 Essence of tuberose fl.oz. 3 Spirit of vetivert fl.oz. 1 Oil of rose fl.dr. 2 Oil of rose geranium fl.dr. 1 Oil of sandal fl.dr. 1 Oil of neroli fl.dr. 1 III. Oil of sandalwood m. 15 Oil of cedarwood m. 75 Oil of rose, synthetic m. 75 Oil of cassie, synthetic fl.dr. 2 Cumarin gr. 20 Heliotropin dr. 2j^ Tincture of artificial musk.. fl.oz. i l / 2 Alcohol, to make fl.oz. 32 V. Vanillin gr. 8 Oil of bergamot m. 30 Oil of rose geranium m. 30 Oil of rose, synthetic fl.dr. 1 Oil of sandalwood fl.dr. 1 Oil of neroli fl.dr. 1 Solution of artificial musk 1% fl.dr. 4 Tincture of orris, stronger, .fl.oz. 4 Alcohol, No. 2 fl.oz. 23 Cinnamon water fl.oz. 2 Orange flower water fl.oz. 2 Dissolve the oils, vanillin, and solu- tion in the alcohol, and add the waters. Frangipanni (Roman) Extract. Musk gr. 12 Ambergris gr. 3 Vanilla, cut fine and tritur- ated dr. 1 Tonka, bruised dr. 2 Essence of cassie fl.dr. 2 Essence of rose fl.dr. 2 Essence of orange flowers. fl.dr. 2 Essence of tuberose fl.dr. 2 Stronger tincture of orris, .fl.oz. 2^2 Oil of rose drops 22 Oil of cedar, Lebanon. .. .drops 22 Oil of rose geranium. .. .drops 10 PERFUMES. 903 Oil of neroli petale drops 12 Oil of orange (from bitter orange peel) drops 3 Alcohol fl.oz. 14 Mix and macerate for several months, agitating occasionally. Harvest Queen Extract. Essence of cassie fl.oz. 2 Essence of tuberose fl.oz. 2 Essence of rose fl.oz. 2 Essence of orange flowers, .fl.oz. 2 Essence of reseda fl.oz. 1 Tincture of tonka fl.oz. 2 Tincture of musk fl.oz. 1 Spirit' of rose geranium fl.oz. i l / 2 Cumarin gr. 30 Alcohol fl.oz. 2 l / 2 Hawthorn Blossom Extract. Essence of violet , Essence of orange flowers, Essence of cassie , Essence of jasmine Essence of rose Tincture of tolu Tincture of tonka Tincture of vanilla Tincture of musk Tincture of ambergris Aubepine .fl.oz. 3 T / 2 .fl.oz. 3/ 2 .fl.dr. 14 .fl.dr. H .fl.dr. 14 .fl.oz. 1 .fl.dr. 7 .fl.dr. 7 .fl.dr. 4 .fl.dr. 3 .fl.dr. 2 Heliotrope Extract. Tincture of vanilla fl.oz. 8 Tincture of ambergris fl.oz. 1 Tincture of civet fl.oz. 1 Compound spirit of rose fl.oz. 3 Oil of bitter almond drops 5 Essence of rose....". fl.oz. 3 II. Spirit of bergamot fl.oz. 6 Tincture of Siam benzoin. .. .m. 30 Vanillin ., . . gr. 2 Heliotropin gr. 10 Alcohol fl.oz. 9 Mix and dissolve. III. Heliotropin fl.dr. 5 Cumarin gr. Vanillin gr. Tincture of Siam benzoin, .fl.oz. Tincture of civet fl.oz. Essence of tuberose fl.oz. Essence of orange flowers, .fl.oz. Essence of jasmine fl.oz. Essence of rose fl.oz. Alcohol fl.oz. 40 2 1 1/2 2V 2 2 X A 6 6 12H Heliotrope (White) Extract. I. Essence of jasmine fl.oz. 4 Essence of rose fl.oz. 2 Essence of tuberose fl.oz. 2 Spirit of ylang ylang fl.dr. 6 l / 2 Tincture of civet fl.dr. 6 Tincture of musk fl.dr. 1 Heliotropin gr. 50 Cumarin gr. 20 Alcohol, to make fl.oz. 16 Mix and dissolve. II. Heliotropin m. 75 Oil of clove drop 1 Cumarin gr. 15 Oil of jasmine fl.dr. 2 Alcohol, No. 2 fl.oz. 32 Hesperis Extract. Essence of cassie fl.oz. 3 Essence of orange flowers, .fl.oz. 3 Tincture of musk fl.dr. 4 Tincture of Siam benzoin. . .fl.oz. 2 Tincture of tonka fl.dr. $y 2 Oil of bergamot fl.dr. 2 Oil of clove fl.dr. 1 Spirit of lavender fl.oz. 2 x / 2 Spirit of rose fl.dr. 4' Rose water ". fl.dr. 4 Alcohol, to make fl.oz. 16 Honeymoon Extract. Essence of jasmine fl.oz. 3^2 Essence of rose fl.oz. 3 l / 2 Essence of violet fl.oz. 3 Spirit of ylang ylang fl.oz. s l A Tincture of musk fl.oz. 1 Tincture of ambergris fl.dr. 6 Solution of ionone, 10% m. 15 Alcohol , fl.dr. 6 Honeysuckle Extract. I. Essence of rose fl.oz. 4 Essence of violet fl.oz. 4 Essence of tuberose fl.oz. 4 Tincture of vanilla fl.oz. 1 Tincture of tolu fl.oz. 1 Tincture of musk fl.oz. 1 Spirit of bitter almond fl.dr. 3^ Spirit of neroli fl.dr. 1 r > Alcohol fl.dr. 4 II. Oil of rose m. 30 Oil of bergamot m. 30 Oil of angelica drops 3 Oil of sandalwood drops 15 Vanillin gr. 6 Solut. oil of rose fl.oz. 8 Solut. oil of jasmine tl.oz. S Solut. oil of violet fl.oz. 8 Alcohol, No. 2. to make fl.oz. 32 904 THE STANDARD FORMULARY The three solutions mentioned are of the concrete oils in the proportion of i ounce to the gallon of alcohol. Hyacinth Extract. I. Hyacinthin dr. \ l / 2 Oil of neroli bigarade drops 30 Tincture of musk fl.dr. 2 l / 2 Tincture of benzoin fl.dr. 5 Essence of jasmine fl.oz. 3 Alcohol fl.oz. 12 Orange flower water, triple. fl.oz. 1/2 II. Hyacinthin gr. 90 Solution of ionone, 10% m. 10 Essence of rose fl.oz. 4^ Essence of orange flowers, .fl.oz. 3 Essence of violet fl.oz. 3 Essence of cassie fl.oz. V/2 Tincture of vanilla fl.oz. 1/2 Imperatrice Extract. Spirit of rose fl.dr. 10 Spirt of rose geranium. .. .fl.oz. 2 Spirit of santal fl.oz. 3 Spirit of ylang ylang fl.oz. 1 Essence of orange flowers, .fl.oz. V/2. Tincture of vanilla fl.oz.'" V/2 Tincture of musk fl.oz. V/2 Cumarin gr. 12 Alcohol fl.oz. 4 Ixora Extract. Essence of cassie fl.oz. 5 Essence of reseda fl.oz. 5 Essence of tuberose fl.oz. 3^2 Spirit of orris fl.oz. 3^2 Tincture of Siam benzoin. . .fl.dr. 3 Tincture of musk fl.dr. 2/2 Oil of bergamot m. 75 Jasmine Extract. Essence of jasmine fl.oz. 25 Essence of tuberose fl.oz. 5 Essence of orange flowers, .fl.oz. 2^2 3 4 I. Tincture of Siam benzoin. . .fl.oz. Tincture of musk fl.dr. Jockey Club Extract. II. Compound spirit of rose. .. .fl.oz. 4 Essence of rose fl.oz. 1 Essence of tuberose fl.oz. 4 Essence of cassie fl.oz. 2 Essence of jasmine fl.oz. 1 Essence of orange flowers. . .fl.oz. 1 Tincture of civet fl.oz. 2 Tincture of musk fl.oz. 1 Essence of tuberose fl.oz. s 1 / Essence of cassie fl.oz. 2 l / 2 Essence of jasmine. . fl.oz. I. Compound of spirit of rose. fl.oz. 3 l / 2 Spirit of ambrette fl.oz. 1 Spirit of neroli fl.dr. 2/2 Tincture of civet fl.dr. 4 Alcohol, to make fl.oz. 16 III. Oil of rose fl.dr. 2 Oil of bergamot fl.dr. 2 Tincture of civet fl.oz. 2 1 / Vanillin gr. 30 Solut. oil of cassie fl.oz. 8 Solut. oil of tuberose fl.oz. 8 Solut. oil of jasmine fl.oz. 8 Alcohol fl.oz. 8 The solutions mentioned are of the concrete oils in the proportion of one ounce to a gallon of alcohol. Kew Garden Flowers Extract. Essence of orange flowers. . .fl.oz. 5 Essence of tuberose fl.oz. 2/2 Essence of cassie fl.oz. 2^ Essence of jasmine fl.oz. 2^ Spirit of rose geranium fl.oz. 2 Tincture of musk fl.dr. 4 Tincture of ambergris fl.dr. 3 Kiss-Me-Quick Extract. Essence of cassie fl.oz. 2^ Essence of jasmine fl.dr. 10 Essence of tuberose fl.dr. 10 Tincture of vanilla fl.dr. 3 Tincture of Siam benzoin. . .fl.dr. 2 Stronger tincture of orris, .fl.dr. 2 Tincture of musk fl.dr. 1 Spirit of bergamot fl.dr. 7 Spirit of neroli fl.dr. 6 Alcohol fl.oz. 9 II. Essence of cassie fl.oz. 7 Essence of jasmine fl.oz. 3^2 Essence of tuberose fl.oz. 3H Tincture of vanilla fl.dr. 4 Tincture of musk fl.dr. 4 Tincture of ambergris. . . .fl.dr. 3 Tincture of Siam benzoin m. 45 Stronger tincture of orris m. 75 Alcohol fl.dr. 4 Lavender Extract. Essence of rose fl.oz. 2 Spirit of lavender fl.oz. 10 Alcohol fl.oz. 4 Lilac Extract (Lilac Blossom — White Lilac). I. Essence of tuberose fl.oz. 12 Essence of orange flowers, .n.oz. 3 Tincture of civet fl.dr. 4 Spirit of ylang ylang fl.dr. 4 Oil of bitter almond drops 3 PERFUMES. 905 II. Terpineol fl.dr. 10 Heliotropin gr. 30 Oil of ylang ylang m. 75 Tincture of civet fl.dr. 4 Essence of jasmine fl.oz. 12^2 Essence of rose fl.oz. g l / 2 Alcohol fl.oz. 8 Lily (Gold) Extract. Nerolin m. 15 Linalool m. 25 Vanillin gr. 25 Oil of cassie, synthetic fl.dr. 1 Tincture of artificial civet.. fl.dr. 3 Essence of jasmine fl.oz. 2 Essence of orange flowers, .fl.oz. 4 Essence of rose fl.oz. j l / 2 Essence of tuberose fl.oz. 15 Alcohol fl.oz. 3 Lily (White) Extract. Essence of rose fl.dr. 20 Essence of orange flowers, .fl.dr. 10 Essence of cassie fl.dr. 10 Tincture of vanilla fl.dr. 14 Spirit of clove fl.dr. 4 Alcohol fl.oz. 9 Lily-of-the-Valley Extract. (White Pond Lily Extract.) Essence of tuberose. fl.oz. 8 Essence of jasmine fl.oz. 1 Essence of orange flowers. . .fl.oz Essence of cassie fl.oz Essence of rose fl.oz Compound spirit of rose fl.oz Oil of bitter almond ..drops Tincture of vanilla ..fl.oz. I II. Essence of rose fl.oz. Essence of violet fl.oz. Essence of jasmine fl.oz. Essence of cassie fl.oz. Spirit of linaloe fl.oz. Spirit of ylang ylang fl.dr. Compound spirit of rose... fl.dr. Spirit of neroli fl.dr. Tincture of musk fl.dr. Oil of mace, volatile drops Alcohol fl.oz. Essence- of rose, second wash- ing, to make fl.oz. III. Heliotropin drops Vanillin gr. Oil of rose geranium drops Oil of sandalwood drops Oil of coriander drops Oil of linaloe fl.dr. Tincture of civet fl.oz. 4 2 1 1 6H 4 2/2 1 6 2 16 Solut. oil of tuberose fl.oz. 12 Solut. oil of jasmine fl.oz. 12 The solutions mentioned are of the concrete oils in the proportion ounce to the gallon of alcohol. Liriodendron Extract. Essence of cassie fl.dr. Essence of tuberose fl.dr. Essence of orange flowers. . .fl.dr. Tincture of Siam benzoin. . .fl.oz. Tincture of civet fl.oz. Tincture of orris fl.oz. Spirit of bergamot fl.oz. Spirit of rose fl.dr. Alcohol fl.oz. Locust Blossom Extract. I. Essence of jasmine fl.oz. Essence of cassie fl.oz. Tincture of vanilla ....fl.oz. Tincture of civet fl.oz. Alcohol fl.oz. II. Essence of jasmine Essence of cassie Essence of tuberose... Tincture of vanilla... Tincture of civet Tincture of ambergris Spirit of ylang ylang. of iy 2 iy 2 sy 2 .fl.oz, 8 .fl.oz. 4 .fl.oz. .fl.oz. .fl.oz. .fl.dr. .fl.dr. Heliotropin gr. Lurline Extract. Essence of rose fl.oz. Essence of jasmine fl.oz. Essence of cassie fl.oz. Spirit of bergamot fl.oz. Spirit of rose fl.dr. Spirit of santal fl.dr. Tincture of civet fl.oz. Tincture of ambergris fl.dr. Oil of lavender m. Alcohol fl.oz. Marie Stuart Extract. Essence of cassie fl.oz. Essence of orange flowers Essence of rose Compound spirit of rose. Spirit of bergamot Spirit of rose geranium.. Spirit of patchouly .fl.oz. .fl.oz. .fl.oz. .fl.dr. .fl.dr. .fl.dr. Tincture of musk. fl.dr. Tincture of tonka fl.dr. Tincture of tolu fl.dr. Tincture of Siam benzoin, .fl.dr. Cumarin gr. Oil of verbena m. Alcohol fl.oz. Mix and dissolve. 4 2/2 2/2 3 5 4 I 3 70 2 2 2 4 12 10 2 6 5 4 25 15 I 900 THE STANDARD FORMULARY May Bells Extract (Mabel Bouquet). Essence of jasmine fl.oz. 3*4 Ylang ylang extract No. 1.. fl.oz. 3 J / 2 Stronger tincture of orris, .fl.oz. 2% Fluid extract of cardamom. . .m. 30 Alcohol fl.oz. 6V 2 The fluid extract may be replaced by 3 drops of oil of cardomom or by 30 gr. of freshly powdered cardamom. May Blossom Extract. Essence of jasmine fl.oz. 4 Essence of rose fl.oz. 2 x / 2 Essence of reseda fl.oz. 2 l / 2 Essence of orange flowers, .fl.oz. \ l / 2 Spirit of orris fl.oz. i l / 2 Spirit of ylang ylang fl.dr. 6 Tincture of musk fl.dr. 2 Tincture of ambergris fl.dr. 2 Oil of bergamot fl.dr. 2 Heliotropin gr. 30 Alcohol fl.oz. 2 l / 2 May Fern Extract. Essence of tuberose fl.oz. 3 Essence of jasmine fl.oz. 3 Essence of rose fl.oz. 3 Essence of violet fl.oz. i l / 2 Essence of cassie fl.oz. i x / 2 Spirit of orris fl.oz. I Tincture of vanilla fl.oz. 1 Tincture of musk fl.dr. 4^2 Tincture of civet fl.dr. 2 l / 2 Tincture of Siam benzoin, .fl.dr. 2 Oil of veteivert m. 30 Oil of rose geranium m. 30 Oil of rose m. 30 Oil of santal m. 30 Oil of bergamot m. 30 Oil of Canada snakeroot. .drops 5 Meadow Queen Extract. Essence of cassie fl.oz. 4 Essence of orange flowers, .fl.oz. 4 Essence of jasmine fl.oz. 4 Spirit of orris fl.oz. 1 Tincture of tonka fl.oz. 1 Tincture' of civet fl.dr. 4 Oil of bergamot fl.dr. 2 Oil of bitter almond m. 15 Alcohol fl.dr. 10 Mikado Bouquet Extract. Lily of the valley extract, .fl.oz. 8 Spirit of sandal fl.oz. i l / 2 Spirit of rose fl.dr. 6 Spirit of vetivert fl.dr. 6 Spirit of cedarwood fl.oz. 3 Tincture of civet fl.oz. 1 Tincture of musk fl.dr. 4 Oil of verbena m. 25 Oil of patchouly m. 15 Alcohol fl.dr. 4 Millefleurs Extract (Thousand Flowers). Compound spirit of rose fl.oz. 3 Essence of rose fl.oz. 1 Essence of jasmine fl.oz. 4 Essence of orange flowers. . .fl.oz. 2 Essence of cassie fl.oz. 2 Stronger tincture of orris. . .fl.oz. 2 Tincture of tonka fl.oz. 1 Tincture of ambergris fl.dr. 4 Tincture of musk fl.dr. 4 Oil of bergamot fl.dr. 2 Oil of bitter almond drops 3 Oil of neroli drops 3 Oil of clove drops 3 II. Essence of rose fl.oz. 3^2 Essence of tuberose... fl.oz. 1% Essence of jasmine fl.oz. 1% Essence of cassie fl.oz. i l / 2 Essence of violet fl.oz. \ l /> Essence of orange flowers, .fl.oz. i l / 2 Spirit of santal fl.oz. 1 Spirit of rose fl.dr. 5 Tincture of vanilla fl.dr. 4 Tincture of musk fl.dr. 4 Tincture of ambergris. .. .fl.dr. 3 Oil of bergamot m. 15 Oil of bitter almond drops 3 Oil of neroli drops 3 Oil of clove drops 3 Monte Carlo Extract. Essence of jasmine fl.oz. 2 Essence of tuberose fl.oz. 2 Essence of violet fl.oz. 2 Spirit of rose fl.oz. 2 Spirit of sandal fl.oz. 1 Spirit of lavender fl.oz. \ l / 2 Tincture of musk fl.oz. 1 Tincture of ambergris fl.dr. 6 Tincture of vanilla fl.dr. 7 Oil of lemon fl.dr. I Mousseline Extract. Esterhazy bouquet extract, .fl.oz. 5 Essence of cassie fl.dr. 7 Essence of jasmine fl.dr. 7 Essence of tuberose fl.dr. 7 Spirit of sandal fl.oz. 5 Compound spirit of rose. .. .fl.dr. 13 Spirit of rose geranium. .. .fl.dr. 3^2 Alcohol fl.oz. 2 Musk Extract. I. Tincture of musk fl.oz. 11 Tincture of civet fl.oz. 1 Compound spirit of rose. .. .fl.oz. 4 This is a rather high priced article but the tincture of musk may be reduced one-half with alcohol and still yield a satisfactory product. PERFUMES. 907 II. I. Essence of orange flowers. . .fl.oz. 2 Essence of cassie fl.oz. 2 Spirit of rose fl.oz. I Tincture of musk fl.oz. l l / 2 Tincture of civet fl.oz. V/2 Tincture of vanilla fl.dr. 4 Tincture of tonka fl.dr. 6 Tincture of tolu fl.dr. 5 Tincture of Siam benzoin. . . .fl.dr. 4 Alcohol fl.oz. 5 Naiad Queen Extract. Spirit of santal fl.oz. Spirit of vetivert fl.oz. Spirit of rose fl.oz. Spirit of patchouly fl.oz. Tincture of musk fl.dr. Tincture of ambergris fl.dr. Oil of verbena m. Alcohol fl.oz. New Mown Hay Extract. Coumarin gr. Vanillin gr. Weaker tincture of orris fl.oz. 3 3 2 2 75 6 II. Vanillin gr. 20 Cumarin av.oz. 1 Anisic aldehyde m. 70 Oil of rose, freed from stearopten m. 25 Oil of rose geranium m. 90 Tincture of musk fl.oz. 2 Essence of orange flowers, .fl.oz. 11 Essence of jasmine fl.oz. 12 Essence of rose fl.oz. 21 Night-Blooming Cereus Extract. Essence of jasmine fl.oz. Tincture of tonka fl.oz. Tincture of civet fl.oz. Tincture of Siam benzoin. . .fl.oz. Spirit of rose fl.oz. Spirit of rose geranium fl.oz. Ocean Spray Extract ("Sea Breeze") Essence of orange flowers. . .fl.oz. 6 Essence of jasmine fl.oz. Compound spirit of rose fl.oz. Spirit of ambrette fl.dr. Spirit of clove fl.dr. Tincture of musk fl.dr. Tincture of vanilla fl.dr. Orange Blossom or Flower Extract. I. Essence of orange flowers, .fl.oz. 12 Essence of cassie fl.oz. 2 Tincture of musk fl.oz. 2 II. Oil of neroli, synthetic m. 160 Tincture of tolu fl.dr. 4 Tincture of musk fl.dr. Spirit of rose fl.oz. Essence of orange flowers. fl.oz. Patchouly Extract. Spirit of patchouly fl.oz. Spirit of rose fl.dr. Alcohol fl.oz. II, Spirit of patchouly fl.dr. Spirit of bergamot fl.oz. Essence of jasmine fl.oz. Essence of rose fl.oz. Tincture of Siam benzoin. . .fl.dr. Alcohol, to make fl.oz. Peach Blossom Extract. Essence of orange flowers, .fl.oz. Essence of tuberose fl.dr. Spirit of lemon fl.dr. Spirit of almond fl.oz. Peru balsam gr. Alcohol fl.oz. II. Essence of cassie fl.oz. Essence of orange flowers, .fl.oz. Essence of rose fl.oz. Solution of ionone, 10% fl.dr. Tincture of musk ...fl.dr. Tincture of civet fl.dr. Oil of ylang ylang, natural or synthetic fl.dr. Heliotropin, crystal gr. Alcohol fl.oz. Peau d'Espagne Extract. Tincture of vanilla fl.oz. Tincture of tonka .fl.oz. Tincture of storax fl.oz. Tincture of benzoin fl.dr. Tincture of civet fl.dr. Tincture of musk fl.dr. Oil of neroli petate m. Oil of bergamot m. Oil of santal m. Oil of rose geranium m. Oil of rose m. Oil of verbena m. Oil of cedarwood m. Oil of lavender, Mitcham. . . .m. Oil of clove m. Alcohol fl.oz. Pearl d'Orient Extract. Essence of cassie fl.oz. 8 Essence of orange flowers. . .fl.oz. 8 Spirit of rose fl.oz. 3 Spirit of ylang ylang fl.oz. Ij4 Tincture tii Siam benzoin fl.dr. 6 Tincture of musk fl.oz. 1 1 / 2 Alcohol fl.oz. 5 2 30 5 4 ioy 2 8/ 2 2 4 2 2 16 3/2 7 13 2*A 24 12 a 1 A 3 3 4 6 1 3o 2 1 1 1 4' 3 3 40 40 40 40 20 20 20 20 20 II THE STANDARD FORMULARY Primrose Extract. Essence of rose fl.oz. Essence of cassie fl.oz. Essence of tuberose fl.oz. Essence of violet fl.oz. Spirit of rose fl.oz. Tincture of ambergris fl.oz. Tincture of civet fl.oz. Solution of ionone, 10% m. Oil of bergamot m. Heliotropin gr. Cumarin gr. Rondeletia Extract. II. II Tincture of musk ....fl.dr. Tincture of ambergris... ....fl.dr. Tincture of vanilla ....fl.dr. Spirit of lavender ....fl.oz. Spirit of clove ....fl.oz. Spirit of bergamot ....fl.oz. Spirit of rose ....fl.oz. Alcohol ....fl.oz. r Spirit of clove ....fl.oz. Spirit of lemon ....fl.oz. Spirit of lavender ....fl.oz. Spirit of bergamot ....fl.oz. Spirit of neroli ....fl.oz. Spirit of rose ....fl.dr. Alcohol ....fl.oz. Rose d'Amour Extract. Essence of rose ....fl.oz. Spirit of rose ....fl.oz. Tincture of musk ....fl.dr. Oil of rose geranium... ....fl.dr. Oil of santal . . .drops Alcohol ....fl.oz. 2/2 2/2 IV2 I I 25 30 30 10 4 2/2 2/2 2 I 2V2 4 7/ 2 3 3 1 2 5 9 3 2 1 1 Rose (Moss) Extract. Compound spirit of rose fl.oz. Essence of orange flowers. . .fl.oz. Essence of rose fl.oz. Tincture of civet fl.oz. Tincture of musk fl.oz. (Rose (Musk) Extract. Essence of rose fl.dr. 10 Essence of tuberose fl.dr. 5 Essence of jasmine fl.dr. 5 Stronger tincture of orris, .fl.dr. 14 Tincture of musk fl.dr. 7 Spirit of orange fl.dr. 2 Spirit of rose fl.dr. 2 Alcohol fl.oz. \0 1 / Rose (Tea) Extract. Essence of rose fl.oz. 4 Essence of orange flowers, .fl.oz. 1 Compound spirit of rose.. fl.oz. 8 Spirit of sandal fl.oz. 2 Stronger tincture of orris, .fl.oz. 1 Oil of rose geranium drops 20 .fl.dr. 12 .fl.dr. 22 .fl.dr. 22 .fl.dr. .fl.dr. .fl.oz. .fl.oz. Essence of rose Compound spirit of rose.. Spirit of rose geranium.. Spirit of sandal Spirit of neroli Stronger tincture of orris Alcohol, to make Rose (Turkish) Extract. Essence of rose fl.oz. Spirit of rose fl.oz. Spirit of rose geranium. .. .fl.oz. Tincture of ambergris fl.dr. Tincture of musk fl.dr. Alcohol fl.oz. Rose (White) Extract. Compound spirit of rose fl.oz. Essence of rose fl.oz. Essence of jasmine fl.oz. Patchouly extract, No. I... fl.oz. 6 1/2 3V2 6 4 4 II. Oil of rose ...fl.dr. Spirit of rose geranium ...fl.oz. Essence of rose ...fl.oz. Essence of jasmine ...fl.oz. Tincture of musk ...fl.dr. Tincture of ambergris.. ...fl.dr. Alcohol ...fl.oz. 2 1/2 2* 6 6 y 2 Rose (Yellow) Extract. Essence of rose fl.oz. 2 Essence of tuberose fl.oz. 2 Tincture of tonka fl.dr. 10 Verbena extract, No. IV fl.dr. 2 l A Alcohol fl.oz. 10^ Rose Geranium Extract. Oil of rose geranium fl.oz. 1 Alcohol fl.oz. 15 Shazada Extract. Essence of rose fl.oz. Spirit of rose fl.oz. Spirit of clove fl.oz. Tincture of civet fl.oz. Tincture of musk fl.oz. Oil of bergamot fl.dr. Oil of lemon fl.dr. Oil of lavender, Mitcham. . .fl.dr. Oil of nutmeg fl.dr. Alcohol fl.oz. Snow Fairy Extract. Essence of jasmine fl.oz. Muguet dr. Tincture of musk fl.dr. Tincture of cardamon fl.dr. Tincture of Siam benzoin. .. .m. Oil of linaloe m. Oil of cananga m. 13 2 4 2 6 5 3 2 4/2 WA 3 5 2 30 90 90 PERFUMES. 909 Spring Flowers Extract. Essence of rose Essence of violet Essence of cassie Compound spirit of rose Tincture of ambergris Oil of bergamot .fl.oz. .fl.oz. .fl.oz. .fl.oz. .fl.oz. .fl.dr. Stephanotis Extract. Essence of cassie. . . Essence of tuberose. Essence of jasmine. Stronger tincture of Tincture of tonka... Tincture of musk... Spirit of rose Spirit of neroli Benzoic acid, from Alcohol, to make. . .fl.dr. .fl.dr. .fl.dr. .fl.oz. .fl.oz. .fl.oz. .fl.dr. .fl.dr. benzoin. . .gr. 30 fl.oz. 16 II. Oil of ylang ylang, synthetic, .m. Oil of rosewood m. Oil of rose m. Oil of bergamot m. Tincture of artificial musk. fl.oz. Tincture of musk seed fl.oz. Tincture of orris, stronger, .fl.oz. Essence of tuberose fl.oz. Essence of rose fl.oz. Essence of jasmine fl.oz. 15 25 30 35 iVa 2V2 5/2 2/ 2 5 5 Alcohol fl.oz. 6 Stolen Kisses Extract. Essence of jonquille fl.oz. Essence of cassie fl.oz. Stronger tincture of orris, .fl.oz. Tincture of tonka fl.oz. Tincture of civet fl.oz. Tincture of ambergris fl.dr. Spirit of rose fl.dr. Oil of citronella (best) drops 8 4 2V Oil of verbena. drops Alcohol -.-:' fl.oz. Sweet Brier Extract. Oil Oil Oil Oil i Spirit Spirit of bergamot. of lemon of lavender. . . of verbena. . . of rose.... of almond . .fl.dr. .fl.dr. .fl.dr. drops .fl.oz. .fl.dr. .fl.oz. .fl.oz. Tincture of musk Alcohol Sweet Hawthorn Extract. Anisic aldehyde m jasmine, synthetic m, 6 6 4 8 2 \2 l /z 2 sy 2 Oil of Oil of neroli . # m. Oil of linaloe, synthetic. ... .m. 45 Solution, of artificial musk (1% in 60% alcohol) fl.oz. 5 Alcohol fl.oz. 24 Distilled water fl.oz. n I. Sweet Pea Extract. Essence of tuberose fl.oz. Essence of orange flowers. . .fl.oz. Essence of rose. fl.oz. Tincture of tonka fl.oz. II. Essence of tuberose fl.oz. Essence of orange flowers. . .fl.oz. Essence of rose .fl.oz-. Tincture of vanilla .fl.dr. Tincture of musk fl.dr. Tincture of ambergris fl.dr. Sweet Vernalia Extract. Essence of cassie fl.oz. Stronger tincture of orris, .fl.oz. Tincture of Siam benzoin. . .fl.dr. Tincture of ambergris fl.dr. Oil of rose geranium m. Cumarin gr. Alcohol fl.oz. Trailing Arbutus Extract. Essence of tuberose fl.oz. Essence of orange flowers, .fl.oz. Essence of cassie fl.oz. Spirit of rose fl.oz. Spirit of ylang ylang fl.oz. Spirit of almond fl.dr. Tincture of vanilla fl.oz. Tincture of musk fl.dr. Tincture of Siam benzoin, .fl.dr. Solution of ionone, 10% m. Heliotropin gr. Vanillin .• gr. Alcohol fl.oz. 7*A zVa 4 2 1V2 5 6 5 80 40 2/2 2V2 1/2 2 I 1/2 2/2 4 2 30 10 6 3 Trefle Extract. Amyl salicylate. Oil of lavender, Mitcham. Oil of clove Oil of ylang ylang Cumarin Vanillin Tincture of musk Tincture of Siam benzoin. Essence of orange flowers. Essence of jasmine Essence of tuberose fl.dr. , . \ m. , . .m. fl.dr. ..gr. ..gr. fl.dr. fl.oz. fl.oz. fl.oz. fl.oz. II. Vanillin gr. Oil of ylang ylang m. Oil of rose m. Oil of bergamot fl.dr. Amyl salicylate fl.dr. Spirit of hyacinth fl.oz. Tincture of artificial civet, .fl.dr. Tincture of artificial musk.. fl.dr. Alcohol tloz. 2 25 40 2 12 12 6 2 5 12V2 12]A 45 10 35 5/2 4 2 28 910 THE STANDARD FORMULARY Tuberose Extract. Essence of tuberose fl.oz. 15 Tincture of ambergris fl.oz. 1 Upper Ten Extract. Tincture of vanilla fl.oz. 4 Tincture of ambergris fl.oz. 3 Stronger tincture of orris.. fl.oz. 3 Compound spirit of rose.. fl.oz. 3 Essence of orange flowers, .fl.oz. 3 Oil of bergamot fl.dr. l]/ 2 Oil of lemon drops 15 Verbena Extract. Essence of orange flowers, .fl.oz. 3 Essence of tuberose fl.oz. 3 Compound spirit of rose. . .fl.oz. 3 Spirit of lemon grass fl.dr. 14 Spirit of neroli fl.dr. 10 Oil of lemon fl.dr. 6 Oil of orange fl.dr. 2 T / 2 Alcohol fl.oz. 3 II. Oil of orange drops 30 Spirit of lemon fl.oz. 10 Spirit of lemon grass fl.oz. 6 Veronica Extract. ...fl.oz. 9 . . .fl.oz. 3 ...fl.oz. \V 2 ...fl.oz. iy 2 ...fl.dr. 4 ...fl.dr. 3 Essence bouquet Essence of rose Essence of jasmine Essence of tuberose Tincture of musk Tincture of ambergris... Violet Extract. Essence of violet fl.oz. II Essence of cassie fl.oz. 2 Tincture of musk fl.oz. 1 Stronger tincture of orris, .fl.oz. 2 II. Ionone, 10% solution fl.dr. 5 Heliotropin m. 30 Oil of orris, concrete dr. 1 Oil of violet, concrete dr. 1 Solution of artificial musk 1% fl.dr. 2 Tincture of civet fl.dr. 4 Solut. oil of jasmine fl.oz. 4 Solut. oil of rose fl.oz. 8 Solut. oil of cassie fl.oz. 16 Alcohol, No. 2, to make. .. .fl.oz. 32 The oil solutions referred to here are solutions of 1 ounce of concrete oil to 1 gallon of alcohol. III. Oil of ylang ylang, artificial, .m. 15 Spirit of rose (from arti- ficial oil) fl.oz. 1 Spirit of neroli (from arti- ficial oil) fl.dr. 4 Solution of artificial musk, 1% m. 100 Solution of oil of orris, concrete, 1% fl.oz. 1 Solution of ionone, i%... fl.oz. 15 Tincture of benzoin fl.oz. 2 Alcohol fl.oz. 10 Violet (Forest) Extract. Spirit of almond fl.dr. 1 Essence of rose. fl.oz. 5 Essence of tuberose fl.oz. 6 l / 2 Essence of cassie fl.oz. 12 Tincture of orris, stronger 3^2 Alcohol fl.oz. 3 This formula is noteworthy because it does not contain violet in any form. Violet (Imperial) Extract. Ionarol dr. 4 Vanillin gr. 10 Oil of orris, concrete dr. 1 Tincture of musk fl.oz. 6 Essence of rose fl.oz. 4 Essence of jasmine fl.oz. 6 Essence of cassie fl.oz. 8 Essence of violet fl.oz. 12 Violet (Mountain) Extract. Ionarol gr. 50 Oil of ylang ylang m. 35 Tincture of musk fl.dr. 3 Essence of violet fl.oz. 18 Essence of violet (2nd washing) fl.oz. 7 Essence of cassie (2nd washing) fl.oz. 2 Essence of jasmine (2nd washing) fl.oz. 4* Violet de Parme Extract (Parmese Violet). Essence of violet fl.oz. 7 Essence of cassie fl.oz. 4 Spirit of orris fl.oz. 2 Compound spirit of rose fl.oz. 1 Spirit of almond fl.dr. 1 Tincture of civet fl.dr. 4 Tincture of ambergris fl.dr. 4 Alcohol fl.oz. 1 Violet (Riviera) Extract. Essence of violet fl.oz. 24 Essence of jasmine fl.oz. 4 Tincture of ambergris fl.dr. 6 Tincture of civet fl.dr. 4 Spirit of bergamot fl.oz. 1 Solution of ionone, 10% fl.dr. 2 Heliotropin gr. 2 Violet (Russian) Extract. Ionone, 10% solution fl.oz. 1 Oil of orris, concrete m. 10 PERFUMES. 911 Oil of ylang ylang m. 15 Essence of violet fl.oz. 15 Essence of violet (3rd washing) fl.oz. 6 Essence of rose (2nd washing) fl.oz. 3 Essence of orange flower (3rd washing) fl.oz. 4H Essence of jasmine (2nd washing) fl.oz. 6 Violet (Spring) Extract. Ionone dr. 2 Vanillin gr. 5 Oil of orris m. 15 Oil of rose geranium m. 15 Tincture of musk fl.oz. 1 Essence of cassie fl.oz. 1^2 Essence of rose fl.oz. V/2 Essence of jasmine fl.oz. 3 Essence of violet fl.oz. 4 Alcohol fl.oz. 20 Violet (Swiss Alpine) Extract. Essence of violet fl.oz. 20 Essence of cassie fl.oz. 5 Essence of rose fl.oz. 1 Spirit of orris fl.oz. 4 Solution of ionone, 10%... fl.dr. 1 Spirit of almond... ^ m. 501 Tincture of ambergris fl.dr. 6 Add chlorophyll if desired. Violet (Tampa) Extract. Essence of violet fl.oz. 24 Essence of cassie fl.oz. 2 Spirit of orris fl.oz. 2 Solution of ionone, 10% fl.dr. 2 Tincture of musk fl.oz. 1 Vanillin gr. 6 Alcohol fl.oz. 1 Violet (Wood) Extract. I. Violet extract, No. II fl.oz. 16 Oil of bitter almond drops 15 II. Essence of violet fl.dr. 13 Essence of cassie fl.dr. 10 Essence of rose fl.dr. 6Yi Essence of tuberose ...fl.dr. 6^ Stronger tincture of orris, .fl.dr. 10 Spirit of almond fl.dr. V/* Alcohol fl.oz. 9 III. Oil of bergamot m. 30 Solution of artificial musk (1% in 60% alcohol} fl.oz. 1 Solution of ionone (1 in 30 in 60% alcohol) fl.oz. 20 Solution of oil of orris, con- crete (1 in 60 in 60% alcohol) fl.oz. 20 West End Extract. Essence of jasmine fl.oz. 1 Essence of cassie fl.oz. 1 Stronger tincture of orris, .fl.oz. 3 Tincture of musk fl.oz. 2 Tincture of storax fl.dr. 2 Spirit of rose fl.dr. 4 Spirit of cedarwood fl.dr. 5 Spirit of neroli fl.dr. 4 Oil of verbena drops 4 Benzoic acid, from bezoin...gr. 15 Alcohol, to make fl.oz. 16 Widow McPhelan Extract. Essence of cassie fl.oz. 2 Essence of violet fl.oz. 1 Stronger tincture of orris, .fl.oz. 3 Spirit of nutmeg fl.dr. 5 Spirit of pimento fl.dr. 5 Spirit of rose fl.dr. 2 Spirit of cinnamon m. 30 Ylang ylang extract No. II. fl.oz. 3 Alcohol fl.oz. 6 Wild Olive Extract. Essence of rose... Essence of violet. . . Essence of jasmine Essence of cassie.. Spirit of bergamot. Spirit of rose Spirit of lavender. . Alcohol, to make.. II. ....fl.oz. ....fl.oz. ....fl.oz. ....fl.oz. ....fl.oz. ....fl.dr. ....fl.dr. ....fl.oz. fl.oz. 5 fl.oz. 2Y2 fl.oz. fl.oz. Essence of rose... Essence of jasmine Essence of cassie.. Spirit of rose Tincture of orris, stronger, .fl.oz Tincture of musk .fl.dr Tincture of ambergris fl.dr Spirit of ylang ylang. .... .fl.dr, Alcohol fl.oz Woodbine Extract. See Honeysuckle Extract. Ylang- Ylang Extract. Spirit of ylang ylang fl.oz. 8 Compound spirit of rose fl.oz. 4 Essence of jasmine fl.oz. 2 Tincture of civet fl.oz. 2 1 1 lY2 2 1/2 II. Essence of jasmine fl.dr. 21 Essence of tuberose fl.dr. 14 Essence of orange flowers, .fl.dr. 7 Spirit of ylang ylang fl.dr. 11 Alcohol fl.oz. o r 2 912 THE STANDARD FORMULARY TOILET WATERS (Perfumed Waters). Toilet waters differ from handker- chief extracts in being much weaker ; frequently they also contain water (in small proportion) which it is usually impossible to add to handkerchief ex- tracts without precipitating some of the constituents. These waters are also cheaper than the "extracts" and. are intended to be used freely, as in the bath, for spraying or sprinkling about in a room, for barber's use, etc. They are usually named after the predomin- ating ingredient, viz., lavender water, violet water, etc. The most popular of the toilet waters are Cologne Water, Florida Water, Vio- let Water, and Bay Rum. The essences, spirits and tinctures used fjor these preparations are the same as those used for making handker- chief extracts. After making these prep- arations, they should be put away for several weeks to allow "ripening" or blending of odors, after which they may be filtered. Besides the waters mentioned herein and for which formulas are given, other waters may be made by suitably dilut- ing the corresponding extract with al- cohol, then adding water until the mix- ture becomes milky, and filtering clear through talcum or calcium phosphate. adapt itself to the contour of the neck and stopper. The split skin should be merely moistened, not soaked, as soak- ing makes it lose its nice appearance. Gold-beater's skin ma}', however, be wetted quite thoroughly. Then draw the skin taut and very smooth over the stopper and over the mouth of the bot- tle and tie it snugly just below the lips with a piece of fine, strong cord. The excess of skin is then to be cut off close with a sharp knife. Some prefer to cut the skin off with scissors, leaving a slight excess beyond the cord of 1/8 to 1/16 inch. Then loop a narrow ribbon of nice color first around the base of the stopper and then around the neck of the bottle and tie the ends in a nice bow. Instead of ribbon, fancy silk cord may be used, this to be tied in a knot, allowing the ends to project a quarter inch or so. These ends should be combed out tassel-like. Very frequently, especially if the stopper is of a fancy design, a piece of narrow split skin is wound once around the base of the stop- per and the lips of the bottle, cutting off the excess as before. Then finish with a piece of ribbon or silk cord. Cologne Water (Eau de Cologne). Cologne water, or "cologne" as it is so frequently denominated, is really a toilet water but the public frequently For example, heliotrope or frangipanni j make it serve as an "extract." Cologne water may be made by diluting helio- trope 'or frangipanni extract as de- scribed. These waters are frequently but improperly called colognes (heliotrope cologne, lilac cologne, violet cologne, etc.). It is customary to "finish off" bottles of toilet water by capping the stoppers. This is done with either split skin or gold-beater's skin, as they are termed. These should be cut into strips slightly wider than the distance from one side of the neck of the bottle to the other side, measuring over the top of the stopper. Just before using moisten the skin to make it pliable and more readily water was first introduced to public no- tice in the 18th century by Johan Maria Farina of the city of Cologne, Germany, whence its name, "Farina" cologne water in sealed bottles is still an article of commerce. The original has been imitated by almost every professional and amateur perfumer but seemingly without success. The primary or essential constituent of cologne water is oil of orange flow- ers to which are added other citrine oils (orange, lemon, bergamot, cedrat). Some of the imitations are made with- out oil of* neroli and may have a va- riety of other ingredients such as musk PERFUMES. 913 and clove. The original cologne water is made by distillation. As in the case of other perfumes, su- perior ingredients will make a first-class product, inferior ingredients a poor product. Cologne water should not be used when freshly made, but should be aged by storing it away in sealed vessels in a dark place for several months, or a year if possible. After being com- pleted it should be preserved in well stoppered bottles, away from strong light and heat. The essences, spirits, and tinctures used in the formulas below are the same as those employed in making handker- chief extracts, which see. Cologne waters are known by various fanciful appellations such as Newport Cologne, Opera Cologne, German Co- logne, Lafayette Cologne, Farina Cologne, Victoria Cologne, Superior Cologne, Imperial Cologne, Oriental Cologne, Royal Cologne, etc. I. Oil of bergamot fl.dr. 4 Oil of lemon .fl.dr. 2 Oil of lavender flowers fl.dr. 1 Oil of neroli fl.dr. I Oil of rosemary m. 105 Acetic ether m. 30 Water fl.oz. 4 Alcohol fl.oz. 28 Dissolve the oils and ether in the al- cohol, add the water, set the mixture aside, in a well-closed vessel for 8 days, then filter in a well-covered funnel. This formula is inserted not because it is especially good but because it was recognized in the U. S. P. 1880 under the names Spiritus Odoratus, Perfumed Spirit, and Cologne Water. It is now mentioned in the N. F. Appendix. II. This is Scoville's formula which was presented at a meeting of the A. Ph. A.: Oil of bergamot fl.dr. 3 Oil of lemon fl.dr. V/ 2 Oil of neroli «. . .fl.dr. 1 Oil of orange m. 30 Oil of rosemary m. 30 Tincture of Siam benzoin. . .fl.dr. 2 Alcohol fl.oz. 28 Orange flower water fl.oz. 3 Dissolve the oils in the alcohol, add the tincture, shake well, and add the water. III. The following formula was awarded a prize about 20 years ago in London as furnishing the best cologne water among 219 samples submitted : Oil of bergamot fl.dr. 2 Oil of lemon fl.dr. 1 Oil of neroli drops 20 Oil of rosemary drops 20 Oil of origanum, true drops 6 Alcohol fl.oz. 19 Orange flower water fl.oz. 1 Dissolve the oils in the alcohol and add the water. IV. This formula won a medal about 20 years ago at a Sydney Exhibition : Oil of cedrat m. 100 Oil of neroli petale m. 60 Oil of neroli bigarade m. 20 Oil of bergamot m. 40 Oil of rosemary m. 40 Alcohol fl.oz. 32 This seems to be very weak in oils but the author claims that other co- lognes contain too great a proportion of oils. Cologne Water With Musk. A toilet water with musk is not a true cologne water because -the original does not contain this ingredient. How- ever so many formulas do contain musk that the best ones have been selected and are given here: V. Oil of neroli petale fl.dr. 1 Oil of rose geranium m. 30 Stronger tincture of orris. . .fl.oz. 2 Tincture of musk fl.oz. 1 Tincture of civet fl.dr. 1 Alcohol fl.oz .28 Mix and filter. VI. Oil of bergamot fl.dr. 3 Oil of lemon fl.dr. 1^2 Oil of lavender flowers m. 30 Oil of orange m. 30 Oil of rose m. 30 Grain musk gr. 1 Alcohol fl.oz. 30 Water, to make fl.oz. 32 914 THE STANDARD FORMULARY Mix the oils and musk with the alco- hol, add the water, macerate for 5 days, agitating frequently, and filter. Lafayette Cologne. VII. Oil of bergamot fl.dr. 3 Oil of lemon fl.dr. i l / 2 Oil of lavender flowers m. 40 Oil of rose m. 30 Oil of neroli m. 20 Musk extract fl.dr. 2 Alcohol fl.oz. 32 Orange flower water fl.oz. 2> l A Oriental Cologne. VIII. Musk gr. 4 Vanilla, the meat or interior, .gr. 10 Asafetida, powder gr. 1 Oil of rose m. 30 Oil of bergamot fl.dr. 6 Essence of jasmine fl.dr. 5 Essence of violet fl.dr. 5 Oil of neroli m. 40 Alcohol fl.oz. 59 Water fl.oz. 5 Mix the musk, vanilla, water and 11 fluidounces of alcohol, macerate for 30 days, add the remaining ingredients, macerate another 30 days, agitating fre- quently, and filter. IX. Oil of bergamot fl.dr. 2 Oil of rose geranium m. 30 Tincture of musk fl.dr. 2 Tincture of vanilla fl.dr. 1 Essence of violet fl.dr. 2 Jockey club extract fl.dr. 2 Alcohol fl.oz. 21 Water fl.oz. 3 Mix all but the water, add the latter gradually with agitation, set aside for some time, and then filter. White Rose Cologne. The following has been known by this name : X. Oil of rose m. 15 Oil of bergamot m. 20 Oil of sweet orange m. 15 Oil of patchouli drops 3 Tincture of musk m. 30 Tincture of ci\*et m. 30 Tincture of orris, stronger, .fl.dr. 2 Essence of jasmine. fl.oz. 1 Alcohol fl.oz. 22 Rose water fl.oz. 2 Dissolve the oils in the alcohol, add the tinctures, and then the rose water. Let stand a few weeks, color pale green with chlorophyll, and filter. Bath Cologne. Cheaper kinds of cologne water are offered under this name. They must also contain none of the animal per- fumes. The following formulas are rec- ommended : XL Oil of bergamot fl.dr. 1 Oil of rosemary fl.dr. 1 Oil of citronella m. 25 Oil of lemon m. 25 Oil of sassafras m. 25 Oil of clove m. 15 Oil of wintergreen m. 15 Acetic ether fl.dr. 1 Alcohol fl.oz. 24 Water fl.oz. 5 Mix, let stand a week or more, and filter. XII. Oil of lavender flowers fl.dr. 1 Oil of bergamot m. 30 Oil of orange m. 30 Oil of rosemary m. 30 Oil of cinnamon drops 5 Alcohol fl.oz. 2> 2 Headache Cologne. By headache cologne is meant a fairly weak cologne water to which menthol has been added in the proportion of 20 to 30 grains to the pint. Or use 30 grains of menthol and 8 grains of cam- phor to the pint. Antiseptic Cologne. Among the various formulas offered under this name the following is the best one: XIII. Oil of bergamot fl.dr. i l / 2 Oil of orange m. 15 Oil of rosemary m. 15 Eucalvptol m. 30 Bornyl acetate gr. 10 Tincture of Siam benzoin. . .fl.dr. 2 Alcohol fl.oz. 22 Water fl.oz. 10 Dissolve the oils, eucalvptol, and- bornyl acetate in the alcohol, add the tincture, then the water gradually with agitation, set aside for a few days, or weeks if possible, and filter. PERFUMES. 915 Bornyl acetate is the odorous princi- ples of oil of pine but is now made synthetically from borneol. It is about 20 times as strong as oil of pine. Eau de Bretfeld. XIV. Oil of bergamot fl.oz. I Oil of lemon fl.dr. 2 Oil of clove m. so Oil of lavender m. 50 Oil of 'neroli m. 40 Oil of rose drops 15 Vanillin gr. 1 Tincture of musk m. 30 Alcohol fl.oz. 54 Water fl.oz. 2 Mix all ingredients except the water, agitate well, add the water, shake again, set aside for 8 days, and filter. Florida Water. This is a toilet water of American origin, but it is now made and used in England, Germany, Japan, and other parts of the world. It is essentially a mixture of citrine oils with lavender to which are added spice oils such as clove, cinnamon, mace and spearmint. Benzoin is the preferred fixative. This ia sometimes replaced by Peru balsam or storax. Musk and similar substances do not belong in this perfume but some formulas do contain it. Any of the following preparations may be cheapened by adding water till the mixture becomes slightly but per- manently turbid, then filtering through calcium phosphate or talcum until clear. As in the case of cologne water, Flor- ida water improves with are. It should be allowed to stand for several months •or even a year before it is used. XV. Oil of lavender flowers fl.oz. 1 Oil of bergamot fl.dr. 4 Oil of clove fl.dr. 2 Oil of rose geranium m. 30 Oil of cinnamon drops 15 Oil of spearmint drops 4 Benzoic acid, from benzoin. . .gr. 20 Water fl.oz. 4 Alcohol fl.oz. 60 Mix the oils and acid with the alco- hol, dissolve by agitation, add the water, agitate again, and filter clear. 58 XVI. Oil of lavender flowers fl.oz. 1 Oil of bergamot fl.dr. 4 Oil of orange fl.dr. 2 Oil of cinnamon fl.dr. 2 Oil of neroli m. 15 Oil of caraway...' drops 10 Oil of spearmint drops 10 Tincture of Siam benzoin. . .fl.dr 4 Water fl.oz. 8 Alcohol fl.oz. 54 Prepare like No. XV. Honey Water. This is an old-time English toilet water. The British Pharmaceutical Codex gives this formula: XVII. Oil of bergamot fl.dr. 1 Oil of lavender flowers m. 20 Oil of clove m. 20 Oil of sandalwood drops 5 Tincture of musk ..fl.dr. 6 Tincture of saffron fl.dr. 1 Honey gr-*40 Orange flower water fl.oz. 2}/ 2 Rose water fl.oz. 2]/ 2 Alcohol, to make fl.oz. 16 Hungary Water. This is a toilet water of older origin than cologne water and is so called be- cause it was a favorite of a former queen of Hungary. The original article was made by distillation but present- day imitations are made from volatile oils. The main constituent is rosemary. XVIII. Oil of rosemary fl.dr. 3 Oil of melissa fl.dr. i l / 2 Oil of lemon fl.dr. 1 ]/ 2 Oil of peppermint drops 8 Essence of rose fl.oz. 3 Essence of orange flower. . .fl.oz. 3 Alcohol fl.oz. 26 Geranium Water. XIX. Oil of rose geranium fl.oz. i l / 2 Stronger tincture of orris. . .fl.oz. i l / 2 Tincture of musk fl.dr. i l / 2 Alcohol fl.oz. 48 Rose water fl.oz. 6 Mix the oils and tinctures with the alcohol, add the water, and filter. Lavender Water. The basis of lavender water is. of course, oil of lavender flowers of which there are two principal kinds of good 916 THE STANDARD FORMULARY quality. The French oil is excellent but the English oil is most esteemed and much higher priced. XX. Oil of lavender, best fl.dr. 6 Alcohol fl.oz. 48 Rose water fl.oz. 16 Magnesium carbonate av.oz. 1 Triturate the oil with the magnesium carbonate, add the alcohol, and then the water, and filter. It may be colored a light brown tint with caramel if de- sired. Lilac Water. XXI. Terpineol fl.oz. V/2 Essence of rose fl.dr. 6 Essence of orange flowers, .fl.oz. l J /> Water fl.oz. 10 Alcohol . fl.oz. 48 XXII Oil of bergamot fl.dr. Oil of lemon fl.dr. Oil of orange fl.dr. Oil of rosemary fl.dr. Terpineol fl.dr. Tincture of Siam benzoin. . .fl.oz. Water fl.oz. Alcohol, to make fl.oz. 64 Verbena Water. XXIII. Oil of verbena fl.dr. 6 Oil of orange fl.dr. 1 ]4 Oil of lemon fl.dr. 1 1 / 2 Oil of neroli m. 25 Essence of jasmine fl.oz. 1^2 Stronger tincture of orris, .fl.oz. 3 Rose water fl.oz. 6 Alcohol fl.oz. 52 Violet Water. This is an article of similar character to those previously mentioned but hav- ing, or at least it should have, the violet odor predominant. Instead of the wash- ings of violet pomade, it is made with oil of orris or ionone. It is usually ex- pected to be a green color. This may be imparted by a trace of chlorophyll. Like all liquid perfumes, violet water should be stored away for some time to allow the odor to develop; this is espe- cially true if it contains ionone. XXIV. Solution of ionone, 10%.. . fl.dr. 1 Oil of sandalwood fl.dr. 2 Oil of neroli m. 30 Oil of bitter almond drops 6 Oil of spearmint drops 12 Tincture of artificial musk.. fl.dr. 1 Tincture of civet fl.dr. 2 Water fl.oz. 16 Alcohol fl.oz. 48 Tincture of the genuine musk may be used but the artificial is to be preferred. XXV. Spirit of ionone, 10% fl.dr. 2 Orange flower water fl.oz 4 Rose water fl.oz. 4 Distilled water fl.oz. 16 Alcohol fl.oz. 36 EATJ VEGETAL (Vegetal). Eau vegetals are the same as toilet waters with 5% of glycerin added. Eau vegetal lilac or violet for example is lilac or violet water toilet containing 5% of glycerin. The vegetals are largely used by barbers. BAY RUM (Spirit of Myrcia). This is also a toilet water the dis- tinctive odor of which is oil of bay leaves. The original" "bay rum" was made by distilling bay leaves with rum, and was obtained from different West India islands where the bayberry tree is indigenous. Instead of the distilled product it is customary to make a solu- tion of oil of bay in alcohol, modifying the odor by such additions as rum and various essential oils. Water is added for cheapening purposes and the mix- ture is finally colored yellowish or yel- lowish-green by the addition of borax, ammonia, or other alkalies, saffron, bay leaves, etc. Regarding the composition of artificial bay rum, there are almost as many for- mulas as there are manufacturers, the variation extending to the proportion of oil of bay and alcohol, the kind and number of modifying constituents and the coloring agent. This preparation was recognized by the U. S. P., 1890. PERFUMES. 917 Oil of bay fl.dr. 4 Oil of orange . m. 15 IOil of pimento m. 15 Alcohol fl.oz. 39 Water ; fl.oz. 25 Mix the oils and alcohol, add the water, set aside in a well-stoppered bot- tle for 8 days and filter.— U. S. P. 1890, and N. F. Appendix. II. Oil of bay fl.dr. 1% Oil of pimento m. 20 I Acetic ether fl.dr. 2 l / 2 Stronger tincture of orris, .fl.dr. 4 New England rum fl.oz. 8 Alcohol fl.oz. 32 Water, to make fl.oz. 64 Mix the oils and tincture with the alcohol, add the rum, then the water, and filter. III. Oil of bay fl.dr. 3 Oil of orange m. 15 Oil of pimento m. 15 Tincture of Siam benzoin. . .fl.dr. 2 Orris root, powder av.oz. $i Water fl.oz. 32 Alcohol fl.oz. 32 „ Dissolve the oils in the alcohol, add the tincture and orris root, shake well, add the water gradually with agitation, and filter clear. A cheap bay rum suitable for barbers' use may be made as follows : IV. Oil of bay fl.dr. 2 Acetic ether... ...fl.dr. 1 Alcohol fl.oz. 24 Water fl.oz. 40 American saffron gr. 15 Talcum, powder av.oz. 1 Mix the oil, ether, alcohol, and talcum, agitate thoroughly, add the water and saffron, agitate for 24 hours, and filter clear. ORGEAT RUM. Oil of bitter almond fl.dr. 1 Tincture of vanilla fl.oz. 2 Alcohol fl.oz. 24 Water fl.oz. 38 Tincture of cudbear fl.dr. 2 Mix and filter clear if necessary. This has been suggested to use in place of bay rum. VIOLET WITCH HAZEL. This is an agreeable variation of the ordinary witch hazel extract and may be used in place of bay rum, especially by barbers for use after shaving: Oil of orris, liquid fl.dr. 1 Essence of jasmine fl.oz. 4 Hamamelis water pints 4 Mix and filter clear through talcum. If desired, it may be colored pale green with chlorophyll. TOILET AROMATIC VINEGARS (Acetic Perfumes). These preparations consist of fragrant essential oils and balsams and other pleasantly odorous substances combined with alcohol and acetic acid. The amount of fragrant substances used should not be so large as to disguise the odor of the acid. The acetic acid adds a refreshing quality to these per- fumes which is absent from the toilet waters. These preparations were origin- ally employed as a prophylactic against infectious diseases for which purpose they were of course entirely ineffective. Later on account of their pungent and reviving odor they were used in the form of a small saturated sponge con- tained in ladies' vinaigrettes which are now generally supplanted by the am- moniated "smelling salts" bottles. If wanted for vinaigrettes, these prepara- tions should be made quite strong with acetic acid and the fragrant substances. Now they are employed for washing in baths or hand basins and are sprinkled about sick rooms to impart a pleasant fragrance. They are also applied to the forehead for headache and fainting spells. Good vinegar or a pure form of acetic acid may be used for these perfumes. If either of these possess anything of an empyreumatic odor, they are unfit for use. The6e preparations may be known simply as toilet or aromatic vinegar, or as lavender, rosemary, eucalyptus, CO logne, witch hazel, cosmetic, floral, anti- septic., hygienic, preventive, etc., vine- 918 THE STANDARD FORMULARY gar according to fancy or according to the main constituents, or may be known by the French title "vinaigre de toilette." Properly speaking, aromatic vinegar is a preparation strong with acetic acid for vinaigrettes, while toilet vinegar is weaker and is intended for the sick room and for bathing. I. Oil of lavender flowers m. 15 Oil of rosemary m. 15 Oil of juniper berries m. 15 Oil of peppermint m. 15 Oil of cassia m. 15 Oil of lemon m. 30 Oil of clove m. 30 Alcohol fl.oz. 1 1 l A Acetic acid, U. S. P fl.oz. nyi Distilled water, to make fl.oz. 60 Dissolve the oils in the alcohol, add the acid, and lastly the water. Warm the mixture for several hours to a tem- perature not exceeding 76° C, taking care there is no loss by evaporation; set it aside for a few days, occasionally agitating, and filter. — N. F. II. The aromatic vinegar of the Ger- man Pharmacopeia differs from the pre- ceding only in containing 50% more of each of the oils. III. Oil of lavender drops 15 Oil of rosemary drops 15 Oil of neroli drops 18 Oil of lemon fl.dr. 2 Oil of bergamot fl.dr. 2 Oil of orange fl.dr. 2V 2 Tincture of musk drops 15 Tincture of Siam benzoin. . .fl.oz. 1 Tincture of tolu fl.oz. 1 Glacial acetic acid fl.oz. 16 Alcohol fl.oz. 45 Mix the oils and tinctures with the alcohol, add the acid, let the mixture stand for several days and filter. IV. Peppermint gr. 365 Rosemary gr. 365 Sage gr. 365 Angelica root gr. 30 Zedoary gr. 30 Clove gr. 30 Vinegar fl.oz. 32 This is the formula of the Austrian Pharmacopeia. The whole is to be macerated for several days, then ex- pressed. V. Oil of cassia m. 30 Oil of lavender flowers fl.dr. 1 Oil of clove fl.dr. V/z Oil of bergamot fl.dr. 2}/ 2 Oil of lemon fl.dr. 2^4 Tincture of tolu, U. S. P m. 160 Tinct. of benzoin, U. S. P. fl.oz. 3% Glacial acetic acid fl.oz. 2 l / 2 Alcohol fl.oz. 32 Water, to make fl.oz. 64 Mix the oils and tinctures with the alcohol, then add the acid and water, shake well, and filter clear. This is the formula of the British Pharmaceutical Codex for toilet vinegar. VI. Oil of cinnamon m. 50 Oil of bergamot m. 100 Oil of thyme, white m. 100 Oil of lavender flowers. .. .fl.dr. 3 l / 2 Oil of orange fl.dr. 3 l / 2 Oil of clove fl.dr. 6 l / 2 Glacial acetic acid, to make. fl.oz. 8 Mix the oils, add the acid, shake well, and filter. This is the formula of the British Pharmaceutical Codex for aromatic vin- egar. This preparation is intended for vinaigrettes. SICK-ROOM PERFUMES. These perfumes consist of a volatile disinfectant dissolved in a toilet water and their purpose is to combine the two desirable properties of disinfection and fragrance. An excellent preparation of this kind is that mentioned under Anti- septic Cologne, which see. Any toilet water may be used, to which has been added suitable disinfectants. For this purpose an oil of pine or fir and bornyl acetate may be added to a toilet water; or a mixture of eucalyptus oil or euca- lyptol and formaldehyde, or of eucalyp- tus oil and chinosol may be used. This water should be sprayed about the room with an atomizer or cloths wetted with the liquid may be suspended in the room. PERFUMES. 919 Aromatic Vapor for Sick Rooms. The following has been suggested: Eucalyptol fl.dr. 5 Oil of thyme, white fl.dr. 2.y 2 Oil of lemon fl.dr. 2V 2 Oil of lavender flowers fl.dr. 2Y2 Alcohol, to make fl.oz. 16 In using this, place a teaspoonful in a pint of water in an open vessel and ap- ply heat. More of the aromatic liquid may be added afterwards to the boiling water if desired. Disinfecting Spray for Sick Rooms. The following may be used for this purpose. It is of course in no sense an aromatic or perfume. Guaiacol fl.dr. 2 Eucalyptol fl.dr. 1 Menthol dr. 1 Thymol gr. 30 Oil of wintergreen fl.dr. 7 Oil of peppermint fl.dr. 5 This is sprayed about the room with an atomizer. SOAP PERFUMES. The following mixtures of odorifer- ous substances are used for perfuming toilet % soaps ; 1 to 2 ounces are required for perfuming 10 pounds of soap. I. Oil of patchouly fl.dr. 4 Oil of clove fl.dr. 4 Oil of sandalwood fl.oz. 1 Oil of lavender flowers fl.oz. 1 Oil of bergamot fl.oz. 1 Oil of rose geranium fl.oz. 2 Tincture of artificial musk. . .fl.oz. 1 II. Oil of petitgrain fl.oz. 1 Oil of sassafras fl.oz. 1 Oil of bergamot fl.oz. I Oil of clove fl.oz. i x / 2 Oil of thyme, white fl.oz. i x /4 Oil of cassia fl.oz. i l / 2 III. Oil of cedarwood fl.dr. 1 Oil of lavender flowers fl.oz. 1 Oil of rosemary fl.oz. I Oil of thyme, white fl.oz. 1 Oil of nutmeg fl.oz. 1 Oil of lavender flowers.. fl.oz. I SOLID OR DRY PERFUMES. Perfumes in the dry condition are less popular than liquid perfumes in spire of the fact that they are of very ancient use whereas the liquids are quite modern products. The oldest civilized peoples, such as the Egyptians, Babylonians, As- syrians, Persians and Jews, used dried leaves, dried flowers, barks, woods, gum- resins, etc., as perfumes and incense. There have been no especial modern improvements in the manufacture of dry perfumes whereas the liquids are constantly undergoing improvement and new combinations of odors are being produced. Among the dry perfumes are sachet powders which are in fine powder, pot pourris in coarse powder, and tablet per- fumes. SACHET POWDERS. Sachet powders are either in fine pow- der or in a coarse (about No. 40) pow- der. The former is known in the trade as the powder, the latter as the granu- lar form. Sachet powders have been devised to represent in a fair degree all the popular odors but the mixtures soon lose their freshness even if kept in well- stoppered bottles. However, a good sa- chet powder is a very useful and dainty form of perfume as it may be enclosed in fancy little bags (called sachets, whence the name) and put with the linen in bureau drawers, in clothes clos- ets, in handkerchief, glove and jewel boxes, in writing cabinets, and the vari- ous articles of clothing and stationery will for a long time diffuse a delicate fragrance which is really more agreeable and delightful but yet less insistent or pronounced than that imparted by the "extracts." Sachet powders never cause the user to seem "loud" or vulgar as do most of the "extracts" unless the latter are used very sparingly. Sachet powders are composed, of such substances as orris root, sandalwood, rose petals, vanilla and tonka beans, lav- ender flowers, vetivert, orange peel, ben- zoin, musk, civet, etc., to which are add- ed vanillin, cumarin and various fra- grant essential oils and liquid synthetic perfumes. Such substances as vanilla 920 THE STANDARD FORMULARY and tonka may be cut up and then bruised in a mortar with granulated orris root until reduced to a suitable condition. Musk and civet should be triturated with orris root to a proper condition before adding to the other in- gredients. Benzoin may be reduced to the correct degree of fineness in a mor- tar. Lavender flowers, rose petals and some other substances may be ground sufficiently fine in a drug mill. Other solid substances may be reduced to a sufficiently fine condition by means which should readily suggest themselves to the competent pharmacist. After all the solid materials have been reduced to a proper state of division, the liquid in- gredients should be added and thorough- ly incorporated. Another way to make sachet powders in the granular form as may be noticed by those who have had occasion to ob- serve the products of perfume houses is to make a body or vehicle of orris root in about No. 40 powder. This is col- ored with alcoholic solutions of aniline dyes, allowing to dry, mixing various colors together and adding some uncol- ored root by way of variety, and finally perfuming. The perfume is to consist of the oils, tinctures, etc., used for mak- ing handkerchief extracts (see Hand- kerchief Extract Formulas), omitting the alcohol from the latter. In this way sachet powders of good appearance and odor may readily be made. Not enough odorous material should be added to cause the powder to leave an oily stain. Similarly sachet powders may be fresh- ened from time to time by the addition of a small amount of the corresponding "extract," viz., violet extract to violet sachet powder, etc. To obtain good sachet powders the best materials cnly should be employed, as in no other way can a satisfactory product be obtained. All the solids, or- ris, rose petals, orange peel or flowers, vanilla, etc., should be Perfectly fresh and of good quality ; the volatile oils and synthetics should be of superior quality as described in previous paragraphs. After being mixed, sachet powders should be allowed to stand a few days to permit the odors to blend thoroughly. They should be preserved in rather small (about 4-ounce), well-stoppered bottles, to prevent both evaporation ,and oxida- tion, in location not exoosed to excessive heat or light. Cassie or Acacia Sachet. Cassie flowers av.oz. 8 Orris root av.oz. 8 Pass each separately through a mill to reduce to tolerably fine powder, then mix, and pass through the mill again, to reduce to finer powder. Clove Pink Sachet. Orris root av.oz. 8 Lavender flowers ' av.oz. 4' Patchouly leaves av.oz. 2 Cloves av.oz. 1 Deer-tongue leaves av.oz. 1 Pimento av.oz. y 2 Musk gr.- 8 Oil of rose drops 40 Oil of lavender flowers drops 40 Oil of neroli ■ drops 48 Oil of sandalwood drops 80 Mix the first six ingredients, grind to a moderately fine powder, triturate the musk to an intimate mixture with a por- tion of this powder, add the remainder of the powder and the oils, and mix the whole thoroughly. If the deer-tongue is not available it may be replaced by 34 or H as much tonka. Essence Bouquet Sachet. Orange peel, recently dried. av.oz. 4 Sandalwood av.oz. 4 Rose petals av.oz. 4 Orris root av.oz. 4 Musk gr. 2 Cumarin gr. 4 Vanillin gr. 4 Oil of rose drops 12 Oil of bergamot drops 12 Oil of neroli drops 5 Oil of ylang ylang drops 5 Oil of cassia drops 5 Oil of rose geranium drops 4 Oil of bitter almond drops 3 Essence of jasmine fl.oz. 1 Mix the first four ingredients, grind PERFUMES. 921 to powder in a mill, triturate the musk, cumarin and vanillin with a portion of the ground material, add to the remain- der of the powder, now add the oils and essence, and again mix well. Field Flowers Sachet. Calamus root av.oz. 4 Lavender flowers av.oz. 4 Rose petals av.oz. 4 Carawa}' < • • av.oz. 2 Marjoram av.oz. 2 Peppermint av.oz. 2 Thyme av.oz. 2 Rosemary av.oz. 1 Cloves dr. $ J / 2 Musk gr. 8 Reduce the various solids to suitably fine powder by grinding in a drug mill; rub up the musk thoroughly well with a small portion of this powder, then in- corporate the remainder of the powder. Heliotrope Sachet. I. Franglpanni Sachet. Orris root av.oz. 8 Rose petals av.oz. 8 Vanilla av.oz. l / 2 Benzoin av.oz. 14 Oil of sandalwood... fl.dr. 2 Oil of neroli fl.dr. I Oil of lavender flowers fl.dr. I Oil of bergamot fl.dr. 1 Oil of cassia drops 2d Oil of pimento drops 40 Oil of rose drops 32 Grind the orris and rose separately to coarse powder, mix, pass through the mill again to reduce to somewhat finer pow- der, triturate the vanilla to powder with a portion of this mixture, also reduce the benzoin to powder, mix the whole, add the oils, and triturate to an intimate mixture. II. Orris, powder av.oz. 12 Vetivert av.oz. 1 Sandalwood av.oz. 1 Vanilla av.oz. 1 Tonka av.oz. l / Oil of neroli drons 15 Oil of bergamot drops 15 Oil of rose geranium drops 15 Oil of sandalwood drops 10 Oil of rose drops 8 Tincture of musk fl.dr. 2 Tincture of civet fl.dr. I Prepare like the preceding. av.oz. 8 av.oz. 4 av.oz. 2 av.oz. 1 gr. 20 Orris root, cut. . Red rose petals. Tonka Vanilla Musk Oil of bitter almond drops 2 Mix the first two ingredients and grind to powder in a mill; contuse the vanilla, tonka, and sufficient of the orris root together until the first two are re- duced to a fine powder; triturate the musk and oil, the latter first dissolved in a small amount of alcohol, with a portion of this powder, add the remain- ing ingredients, and mix the whole inti mately in a mortar. II. Tonka beans av.oz. 4 Orris root av.oz. 4 Rose petals av.oz. 4 Benzoin av.oz. 1*4 Vanillin dr. 1 Heliotropin dr. 3 Oil of rose geranium m. 20 Musk residue dr. iY 2 Reduce the tonka, orris and rose pet- als to powder by grinding in a mill, con- tuse the benzoin in a mortar, triturate vanillin and musk residue with a portion of the powdered material until well mix- ed, then incorporate the oil and helio- tropin, and mix the whole together thor- oughly. The musk residue is what remains of the musk after extraction with alcohol in making the tincture. Jockey Club Sachet. I. Lavender flowers av.oz. 2 Rose petals av.oz. 6 Orris av.oz. 8 Vanilla dr. 2 Musk gr. 16 Essence of jasmine fl.oz. 1 Oil of sandalwood drops 80 Oil of rose drops 40 Oil of neroli drops 20 Reduce the first three ingredients to powder by grinding in a mill, contuse the vanilla with a portion of the ground mixture to powder: also triturate the musk with a portion of the powder inti- mately, add the oils and essence, and 922 THE STANDARD FORMULARY mix the whole thoroughly by trituration in a mortar. [I. Orris, powder av.oz. 12 Sandalwood, ground av.oz. 2 Oil of bergamot fl.dr. 2 Oil of rose drops 8 Tincture of musk fl.dr. 4 Tincture of civet fl.dr. 2 Mix the orris and sandal, add the other ingredients, and triturate until the whole is thoroughly incorporated. Lavender Sachet. I. Lavender flowers av.oz. 12 Benzoin av.oz. 3 Oil of lavender flowers fl.dr. 1^2 Reduce the lavender and benzoin each separately to fine powder, add the oil and triturate the whole thoroughly until well mixed. II. Lavender flowers av.oz. 12 Benzoin av.oz. 3 Oil of bergamot fl.dr. i l A Oil of lavender flowers fl.dr. 2]/ 2 Prepare like the preceding. Marechale Sachet. Sandalwood av.oz. 6 Orris root av.oz. 5 Rose petals av.oz. 4 Clove av.oz. 3 Cassia bark av.oz. 3 Musk gr. 4 Reduce the first five ingredients to moderately fine powder by grinding in a mill, add the musk and mix well by trituration. Millefleurs Sachet. Orris av.oz. 8 Lavender flowers av.oz. 3 Coriander av.oz. 2 Clove av.oz. 1 Cassia buds av.oz. 1 Benzoin dr. 2 Nutmeg dr. 2 Vanilla av.oz. y 2 Musk gr. 20 Oil of sandalwood drops 40 Oil c*f rose drops 20 Oil of neroli drops 16 Oil of lavender (English) .drops 16 Oil of patchouly drops 8 Oil of verbena drops 8 Contuse the orris and nutmeg, add the lavender, clove, cassia, and coriander, grind all together in a mill to moderate- ly fine powder, triturate the vanilla and musk each with a portion of this pow- der until well mixed, contuse the ben- zoin to powder, mix the whole, add the oils and mix all thoroughly by tritura- tion. II. Lavender flowers av.oz. 2 Orris av.oz. 2 Rose petals av.oz. 2 Benzoin av.oz. 2 Clove av.oz. iJ4 Tonka av.oz. J / 2 Vanilla av.oz. l / 2 Sandalwood av.oz. l / 2 Cardamon dr. 5 Cassia bark dr. 5 Musk gr. 6 Grind the lavender, orris, rose petals, sandal, clove, cardamon, and cassia to- gether in a mill to moderately fine pow- der, triturate the vanilla and tonka with a portion of this mixture until reduced to powder, also triturate the musk with another portion until well mixed, con- tuse the benzoin to fine powder, and mix the whole together thoroughly. Musk Sachet. Oil of rose drops 15 Ammonium carbonate gr. 7 Musk gr. 20 Orris, powder av.oz. 16 Mix intimately. The proportions may be altered if desired. The alkali devel- ops the odor of the musk. New Mown Hay Sachet. I. Orris av.oz. Rose petals av.oz. Orange flowers av.oz. Musk seed av.oz. Tonka av.oz. Benzoin av.oz. Oil of verbena drops 12 Oil of bitter almond drops 12 Grind the orris, rose petals, orange flowers and musk seed together in a mill to moderately fine powder, triturate the tonka with a portion of this to fine powder, also contuse the benzoin to powder, mix all, add the oils, and mix the whole intimately by trituration. 3 3 1/2 1/2 34 PERFUMES. 923 II. Orris, powder av.oz. 1 1 Tonka av.oz. i l / 2 Vanilla av.oz. V/ 2 Oil of bitter almond drops 2 Oil of rose drops 6 Oil of bergamot drops 12 Oil of rose geranium drops 24 Tincture of musk fl.dr. 2^ Triturate the tonka and vanilla with the orris to fine powder, add the oils and tincture, and mix well by tritura- tion. Opoponax Sachet. Orris av.oz. 8 Rose petals ..._. av.oz. 2Y2 Cassie flowers av.oz. 2 l / 2 Tonka dr. 5 Vanilla dr. 4 Musk . ...gr. 75 Oil of rose drop 1 Oil of citronella drops 3 Oil of lemon drops 5 Oil of patchouly drops 5 Oil of rose geranium drops 10 Oil of bergamot drops 20 Tincture of civet m. 40 Mix the first three ingredients, grind to moderately fine powder in a mill, trit- urate the vanilla and the tonka with a portion of this powder until a fine mix- ture is produced, add the remainder of the ground mixture, the oils and the tincture, and mix well by trituration. Oriental Sachet. Orris av.oz. 2 Calamus av.oz. 2 Orange peel, recently dried. av.oz. 2 Rose petals av.oz. 2 Musk seed av.oz. 1 Sandalwood av.oz. 1 Rosewood av.oz. 1 Clove av.oz. x / 2 Cassia av.oz. y 2 Benzoin av.oz. y 2 Myrrh av.oz. y 2 Tincture of ambergris m. 20 Mix all but the myrrh, benzoin and tincture; grind to moderately fine pow- der, contuse the benzoin and myrrh to powder, mix all, add the tincture of am- bergris, and triturate until well mixed. Patchouly Sachet. I. Patchouly herb av.oz. 8 Lavender flowers av.oz. 3 Orris av.oz. 2 .av.oz. 6 .av.oz. 3 .av.oz. 3 av.oz. 3 .av.oz. 1 Clove av.oz. 1 Oil of bergamot fl.dr. 1 Oil of patchouly drops 2 Tincture of ambergris m. 30 Tincture of musk m. 30 Mix the first four ingredients, grind to moderately fine powder in a mill, add the other ingredients and mix well. Peau d' Espagne Sachet. Orris root Sandal wood, yellow Cedar wood , Lavender flowers . . . Benzoin Musk residue gr. 130 Civet residue gr. 65 Oil of bergamot fl.dr. 2 Oil of neroli, artificial m. 45 Oil of jasmine, artificial m. 30 Oil of verbena m. 15 Reduce the orris, sandal, lavender and cedar wood to powder by grinding in a mill, contuse the benzoin in a mortar; triturate the musk and civet residues with a portion of the powder until thor- oughly well mixed, incorporate the oils, and then mix all the ingredients to- gether intimately. The musk and civet residues are what remains of the musk and civet after ex- traction in the making of tinctures. Rondeletia Sachet. Orris av.oz. 12 Lavender flowers av.oz. 6 Clove dr. 1 Musk gr. 12 Tincture of ambergris fl.dr. 2 Oil of rose drops 5 Oil of rose geranium drops 8 Oil of bergamot drops 30 Oil of clove drops 30 Oil of lavender flowers. .. .drops 30 Mix the first three ingredients, grind to moderately fine powder in a mill, trit- urate the musk with a portion of this powder until well mixed, add this to the remainder of the powder, then add the oils and tincture, and mix the whole thoroughly. Rose Sachet. I. Rose petals av.oz. 16 Oil of rose geranium drops 30 Oil of rose drops 30 Tincture of ambergris drops 20 Tincture of musk drops 10 924 THE STANDARD FORMULARY av.oz. 4 av.oz. 4 av.oz. av.oz. 4 m. fl.dr. IOO I Grind the rose petals to moderately fine powder, add the other ingredients, and mix thoroughly. II. Orris av.oz. 6 Rose petals av.oz. 6 Sandal wood av.oz. i Patchouly herb av.oz. Y / 2 Tincture of civet fl.dr. I Oil of rose geranium drops 8 Oil of rose drops 6 Mix the orris, rose petals, sandal and patchouly, grind to moderately fine pow- der in a mill, add the other ingredients and mix well. III. Orris root Rose petals Rosewood Benzoin Oil of rose geranium Oil of rose, synthetic Grind the orris, rose petals and rose- wood in a mill ; contuse the benzoin in a mortar; triturate the oils with a portion of this powder, and mix the whole to- gether thoroughly. Sweet Brier Sachet. Orris, ground av.oz. 13 Sandal wood, ground av.oz. 3 Oil of rose drops 6 Oil of rose geranium drops 6 Oil of bergamot drops 8 Oil of lemon drops 12 Oil of neroli drops 12 Oil of verbena drops 24 Tincture of ambergris m. 45 Tincture of musk m. 45 Mix the whole thoroughly. Verbena Sachet. Orris, ground av.oz. 16 Oil of bergamot m. 40 Oil of verbena or lemon- grass fl.dr. 1 Oil of rose geranium drops 10 Tincture of musk m. 80 Mix the whole thoroughly. Violet Sachet. I. Orris, ground av.oz. 16 Oil of bergam6t drops 10 Oil of bitter almond drops 7 Oil of rose drops 7 Tincture of musk fl.dr. 2 l / 2 Mix the whole thoroughly. II. . .av.oz. 12 ..av.oz. 4 Orris, ground Benzoin Spirit of almond drops Spirit of ionone, 10% fl.dr. I Contuse the benzoin in a mortar to coarse powder, triturate the two spirits intimately with a small portion of the powdered orris, then mix all the ingre- dients together. Wild Flowers Sachet. Canada snake root av.oz. 4 Coriander av.oz. 3 Deer-tongue leaves av.oz. 2 Lavender flowers av.oz. 2 Patchouly leaves av.oz. 1 Calamus root av.oz. y 2 Nutmeg av.oz. T / 2 Oil of bergamot fl.dr. 2 l / 2 Oil of sandalwood drops 80 Oil of neroli drops 40 Oil of verbena drops 20 Oil of patchouly drops 20 Essence of jasmine fl.dr. 1 Break the nutmeg into small pieces, mix with first seven ingredients, grind the whole in a mill to moderately fine powder, add the remaining ingredients, and mix thoroughly. If the deer-tongue is not available it may be replaced by H ounce of tonka bean. Ylang Ylang Sachet. Orange peel, recently dried. av.oz. 6 l / 2 Orris av.oz. 5 Rose petals av.oz. 5 Cumarin gr. I Vanillin gr. 2 Tincture of civet drops 10 Tincture of musk drops 5 Oil of ylang ylang drops 15 Oil of rose drops 10 Oil of bergamot drops 5 Oil of rose geranium drops 3 Essence of jasmine fl.dr. 6 Mix the first three ingredients, reduce to moderately fine powder in a mill, dis- solve the cumarin and vanillin in the re- maining ingredients, and mix the whole thoroughly. PEATJ D'ESPAGNE (Spanish Leather). Small square pieces of chamois skin or white kid are soaked in the following solution for 3 or 4 days : PERFUMES. 925 Oil of rose, synthetic fl.dr. 4 Oil of neroli, synthetic fl.dr. 4' Oil of sandalwood fl.dr. 4 Oil of lavender flowers fl.dr. 2 Oil of lemon fl.dr. 2 Oil of cinnamon m. 30 Linalyl acetate fl.dr. 2 Cumarin gr. 12 Artificial musk dr. 1 Tincture of benzoin fl.oz. 3 The tincture of benzoin for this pur- pose should be made from 2 av. ounces of Siam benzoin and 5 fluidounces of alcohol. Then remove the leather from the liquid, allow it to drain, spread it on a glass plate to dry, and coat one side of the leather (the rough side of the kid) with the following mixture, applying the latter by means of a brush : Benzoic acid, sublimed dr. 2 Musk gr. 12 Civet gr. 12 Gum arabic dr. 6y 2 Glycerin fl.dr. 5 Water fl.oz. iy 2 Rub up the musk and civet thoroughly with the acid and gum, then incorporate the glycerin and water so as to form a smooth mixture. Fold or double the leather over when the two halves will adhere to each other, and allow to dry. This perfumed skin emits its odor for years. It is used instead of sachet bags to place in trunks, drawers, closets, writ- ing desks, glove and handkerchief boxes, etc. Pieces of this skin are also sewed into ladies' clothing and lingerie. GLOVE PERFUME. To overcome the unpleasant natural odor of leather, it is suggested to place sachet bags in the glove boxes. Or a regular glove perfuming powder may be used, made of 2 parts each of powdered orris root and magnesium carbonate and 1 part of talcum. Five ounces of this powder may be perfumed with a mix- ture of Helitropin dr. 3 Vanillin gr. 100 Tincture of civet m. 40 Tincture of Siam benzoin, .fl.dr. 2 l /i This makes a heliotrope odor but other odors may be made, using the in- gredients of handkerchief extracts and omitting the alcohol from the latter. This powder is to be sewed into little bags which are to be put inside in the gloves when the latter are not in use and are kept in the glove boxes. PERFUME LOZENGES. Solid perfumery in the form of loz- enges are quite a novelty. They may be made by taking a suitable mixture of powders, tinting and perfuming it, mak- ing a soft mass or dough with gum and water, rolling out into sheets about J4 or Yz inch thick, cutting into lozenges with a lozenge cutter, and finally drying. These may be carried about in the purse or hand-bag or distributed about in bu- reau drawers, clothes closets, writing desks, etc., like sachet bags. For the basis of the lozenges the fol- lowing will be acceptable : Starch av.oz. 10 Magnesium carbonate av.oz. 5 Orris root, powder av.oz. 1 Dextrin av.oz. 1 Salicylic acid gr. 20 Mix well, acid the tinting and perfum- ing materials, then make a soft dough with water and syrup, and roll out and cut as described before. The salicylic acid is added for the purpose of preventing mou!I Boric acid may be used instead. For the tinting material any suitable aniline dye may be used, first dissolving it in a little alcohol. Pink or pale blue shades make the most attractive appear- ance. For perfuming purposes, to each 8 ounces, the following proportions of od- orous material may be added; Heliotrope. Heliotropin m. 40 Vanillin gr. 30 Tincture of Siam benzoin, .fl.dr. 6 Mignonette. Reseda oil, synthetic m. 30 Geraniol m. 20 Oil of bergamot m. 80 Tincture of Siam benzoin, .fl.dr. 926 THE STANDARD FORMULARY Rose. Oil of rose, artificial drops 15 Oil of rosewood m. 20 Oil of rose geranium m. 75 Tincture of artificial musk....m. 40 Tincture of Siam benzoin, .fl.dr. 4 Lily. Vanillin gr. 4 Heliotropin drops 15 Oil of neroli, synthetic drops 5 Oil of rose geranium m. 40 Tincture of artificial musk m. 40 Tincture of Peru balsam. . .fl.dr. 2 Violet. Ionone, 10% solution fl.dr. 3 Oil of ylang ylang drops 25 Tincture of musk m. 80 Tincture of Siam benzoin. . .fl.dr. 4 The amount of perfume may be va- ried; it may be much increased if de- sired. TABLET OR FROZEN PERFUME. The novelty sold under this name is prepared by melting paraffin in a water bath, adding odorous substances when nearly cool, and pouring into small molds to form tablets of any desired size. The following formulas may be employed in preparing them, each of the mixtures given being sufficient for 4 av. ounces of paraffin. These are intended to be put into bu- reau drawers, clothes closets, writing desks, etc., in place of sachet bags. I. Oil of bergamot fl.dr. 2 Oil of lavender flowers fl.dr. 2 Oil of clove fl.dr. 1 Oil of rose geranium m. 20 Vanillin gr. 10 II. Oil of neroli m. 30 Oil of rose geranium m. 30 Oil of lavender flowers m. 30 Oil of bergamot fl.dr. 1 Oil of clove drops 2 Heliotropin m. 10 III. Oil of linaloe fl.dr. 2 Oil of bergamot m. 20 Oil of lemon in. 20 Heliotropin m. 20 lV. - Oil of ylang ylang fl.dr. 2 Oil of neroli fl.dr. 1 , Oil of sandalwood m. 30 Cumarin gr. 20 Tincture of musk m. 20 Oil of bergamot fl.dr. 4 Oil of lemon fl.dr. 1 Oil of orange fl.dr. 1 Oil of neroli .^ m. 30 Oil of rose geranium m. 20 Oil of rosemary m. 20 Oil of lavender flowers m. 20 POT POURRIS. These are mixtures of odorous sub- stances, in rather coarse condition, to be placed in open jars, called pot pourri jars, and intended for scenting rooms. The individual particles should be of about the size of a snlit pea, and such substances as orris, benzoin, etc., should be reduced to this size by appropriate means. Rose petals are the basic ingre- dient, these forming the body or bulk, of the mixture. In making good pot pourri mixtures the best materials are required. Extra perfume, such as an "extract," may be added to these pot po^rris if de- sired. I. Lavender flowers av.oz. 4 Orris av.oz. 4 Rose petals av.oz. 4 Clove av.oz. 1 Cinnamon av.oz. I Siam benzoin av.oz. 1 Pimento av.oz. 1 Table salt av.oz. 2 Vanilla av.oz. Y\ Musk gr. 100 Oil of bergamot drops 30 Oil of lemon drops 30 Oil of lavender flowers ... drops 15 Oil of sandalwood drops 15 Oil of rose geranium drops 15 Oil of rose drops 2 Tincture of ambergris m. 30 Reduce the orris, rose petals, clove, cinnamon, benzoin, pimento and vanilla to particles of suitable size, add the lav- ender, salt and musk, and then the oils and tincture, and mix well. II. Lavender flowers oz. 8 Rose petals ...oz. 4 Vanilla dr. 1 Clove , dr. 1 Storax dr. 1 PERFUMES. 927 Benzoin dr. I Ambergris gr. 20 Oil of rose drops 20 Prepare like the preceding. SMELLING SALTS (Ammoniated Perfumes). Under the name of "smelling salts," "inexhaustible salts," "Preston salts" and "pungent" there are moist, granular preparations which are aromatized and give off a fragrant odor in connection with the pungent odor of ammonia. Or- iginally these consisted of sponge cut into fine pieces, contained in a wide- mouthed bottle or a vinaigrette, which was saturated with a mixture of ammo- nia water or spirit of ammonia and fra- grant material. Only sufficient liquid was used to saturate the sponge so that when the vessel was inverted none of it would exude. To make a neat-looking product, the pieces of sponge were to be of uniform size and of a light and uni- form color. Nowadays other substances are used for the sponge such as ammonium car- bonate in a coarsely powdered condi- tion. Fine powder should be removed by means of a sieve. There should also be none of the fine powder with which it becomes covered on exposure to the air. Only the translucent pieces should be used as these make the best "salts" and they make a handsome appearance. In- stead of ammonium carbonate, crystal- line potassium sulfate in small pieces is used, it having apparently been found quite satisfactory. Various porous sub- stances will suggest themselves for this purpose, such as small pieces of white pumice stone but this does not give the handsome appearance of the previously mentioned substances. A cheaper article of smelling salts may be made by making a mixture of ammonium chlorid and po- tassium carbonate or lime which slowly evolves ammonia. However, this is not entirely satisfactory and does not make a nice appearance. After the bottle has been filled with sponge, ammonium carbonate, potassium sulfate or whatever else is used, a small amount of ammonia water or spirit of ammonia mixed with perfume is poured over the contents of the bottle. Spirit of ammonia is to be preferred as its alcoholic character makes it a perfect solvent for the essential oils, pomade essences, synthetics, etc., used for the perfume. Not all perfuming agents are satisfactory for use in smelling salts ; lavender has become popular, while musk, civet and other "strong" odors are usually avoided. These preparations are usually dis- pensed in small wide-mouthed bottles which can be well closed; sometimes or- namental glass containers are used but they are valueless for holding these per- fumes unless they can be securely closed with glass stoppers when not in use. These "salts" are used by inhalation in the headaches and fainting spells of ladies. They may be "freshened" or strengthened occasionally by adding a small portion of ammonia water, or, bet- terp-of the original mixture of spirit of ammonia and perfume. The following are some of the for- mulas that are in use: I. Oil of clove drops 10 Oil of lavender flowers drops 30 Oil of bergamot fl.dr. 1 Stronger water of ammonia. fl.oz. 2 Fill the smelling bottles with coarsely powdered ammonium carbonate and add to the salt as much of the ammonia and oils as it will absorb. II. Oil of lemon fl.dr. 1 Oil of lavender m. 30 Oil of clove drops 10 Stronger water o'f ammonia. fl.oz. 3 Fill the smelling bottles with crystal- lized potassium sulfate and pour into each bottle as much of the ammonia mixed with the oils as the salt can re- tain without spilling. This makes a much prettier looking smelling salt than ammonium carbonate, and as it does not cake together like it, the bottle need not be emptied when the ammonia has 928 THE STANDARD FORMULARY evaporated. All that is necessary is to fill it up again with the aromatized am- monia. III. Ammonium carbonate av.oz. 12 Ammonia water fl.oz. 1^2 Oil of lavender flowers fl.dr. 1 Oil of bergamot m. 30 Oil of lemon m. 15 Tincture of musk m. 30 Prepare like any of the preceding. Spirit of ammonia is to be preferred to the water as it dissolves the oils. IV. Camphor dr. 3 Tincture of musk fl.dr. 6 Isoeugenol m. 15 Oil of lemon m. 30 Oil of lavender flowers m. 60 Oil of bergamot m. 75 Alcohol fl.oz. 4 Ammonia water fl.oz. 4 Prepare like any of the preceding. V. Ammonium chlorid av.oz. 7 Potassium carbonate av.oz. 9 Oil of lavender flowers fl.dr. 4 Oil of lemon fl.dr. i]/ 2 Oil of bergamot m. 30 Oil of clove m. 10 Ammonia water sufficient Triturate the ammonium chlorid and potassium carbonate together, add the oils, then incorporate enough ammonia water to moisten, and pack into bottles. This does not make as neat an ap- pearance as the preceding. Lavender Smelling Salts. VI. This may be made by filling suit- able bottles with small, translucent pieces of ammonium carbonate and add- ing the required amount of a solution of 1 fluidram of oil of lavender flowers in 2 fluidounces of spirit of ammonia. If the spirit is not at hand, use a mixture of y 2 ounce of stronger water of am- monia and V/2 of alcohol. VII. Or use the following: Oil of lavender. Mitcham m. 80 Oil of bergamot m. 40 Oil of rose, synthetic drop 1 Isoeugenol m. 15 Tincture of musk m. 50 Alcohol fl.oz. 3 Ammonia water fl.oz. 5 Add this liquid to the ammonium car- bonate or potassium sulfate in a suitable container. Menthol Smelling Salts. This may be made by putting coarsely powdered ammonium carbonate into a suitable container and then adding a sufficient amount of menthol in crystals. Violet Smelling Salts. This may be prepared by placing crushed translucent pieces of ammonium carbonate into a suitable container and adding a sufficient amount of a mixture of violet extract and stronger water or, better, spirit, of ammonia. The liquid may be tinted green with chlorophyll. Other odors may be made, such as heliotrope, by using the corresponding oil or extract. FUMIGATING PREPAKATIONS. These preparations differ from any of the preceding in that their odor is not developed until they are ignited (except the vinegars). They are perhaps the oldest form of perfume if so they may be called. The burning of fragrant sub- stances or "incense" is one of the oldest practices of mankind and was chiefly of a religious or ceremonial character. In the middle ages these substances were used to prevent or drive away disease and to destroy foul odors caused by dis- ease and otherwise. They are still used to overcome bad odors and to act as dis- infectants but they are probably value- less for the latter purpose. Sandalwood, olibanum, myrrh, benzoin, etc., are com- mon ingredients. The odor they pro- duce is balsamic or spicy, not at all of a flowery character. The different kinds of fumigating preparations are pastilles, powders, pa- per, essences and vinegars. Fumigating Pastilles. These are cone-shaped bodies pro- duced by mixing either red saunders or wood charcoal with potassium nitrate, various odorous and odor-producing substances, and mucilage, and making a mass which may be divided and formed PERFUMES. 929 by hand into cones like a rectal supposi- tory, after which they should be dried. Or the cones may be formed by means of a pastille machine. They should be about 54 to i inch long and should have a flat bottom so they will stand up. When used the apex is ignited. Red saunders is used for making the red pastilles while wood charcoal pro- duces the black variety. Potassium ni- trate is added to facilitate the burning. They are frequently burned in rooms to keep away insects like mosquitoes and flies. I. Wood charcoal or red saunders av.oz. 6 Benzoin av.oz. I Cascarilla av.oz. I Myrrh dr. 2^2 Potassium nitrate av.oz. V/2 Oil of nutmeg fl.dr. 3 Oil of clove fl.dr. 3 Mucilage of tragacanth sufficient Powder the benzoin, cascarilla and myrrh, mix with the powdered charcoal or saunders, add the oils, then the po- tassium nitrate dissolved in a little hot water, make a mass with the mucilage, divide and form into cones, and then dry the latter. II. Wood charcoal or red saun- ders, in powder av.oz. 3 Potassium nitrate, powder dr. 3 Oil of thyme m. 15 Oil of caraway m. 15 Oil of rose m. 15 Oil of clove m. 15 Oil of sandalwood m. 15 Oil of lavender flowers m. 15 Mucilage of tragacanth sufficient Mix all and make pastilles as in Nos. I and II. Fumigating Powder or Species. While being similar to the pastilles, fumigating powder is of more variegat- ed composition than the former. It con- tains various woods, barks, and gum resins, besides various colored flowers which impart a handsome appearance. No powdered charcoal is used and fre- quently no potassium nitrate. The for- mer detracts from the appearance of the product while the latter is usually considered not necessary. To the pow- der is added a mixture of aromatic oils and tinctures to make it more fragrant. A still finer appearance may be imparted to the powder by adding orris root in about No. 20 to 40 powder which has been tinted various colors with aniline dyes dissolved in alcohol, also adding some uncolored orris root. The mixture should be in the form of a coarse powder, free from any fine powder as well as from large coarse pieces. It should be preserved in well- stoppered bottles. Fumigating powder is used for the same purposes as fumigating pastilles. In using it, sprinkle it on a hot stove or on live coals. I. Coriander av.oz. \ l / 2 Cassia bark av.oz. l l / 2 Cascarilla av.oz. \V 2 Lavender flowers av.oz. iV 2 Peony flowers av.oz. 1 l / 2 Orris root av.oz. i l / 2 Juniper berries ....av.oz. i l / 2 Rose petals av.oz. 1 l / 2 Blue flowers av.oz. 1^2 Calendula flowers av.oz. i l / 2 Clove av.oz. 1 1 / 2 Oil of bergamot fl.dr. 2 l / 2 Oil of lemon fl.dr. 2 l / 2 Oil of lavender flowers m. 15 Oil of clove m. 15 Oil of cassia m. 15 Tincture of ambergris drops 12 Tincture of musk drops 6 Tincture of benzoin fl.dr. 4 Mix the drugs, reduce to coarse pow- der, and thoroughly incorporate with the oils and tinctures which have previously been well mixed. II. Sandalwood, yellow av.oz. 4*5 Sassafras av.oz. 3 Cinnamon • • av.oz. 1 Clove av.oz. 1 Cascarilla av.oz. % Potassium nitrate av.oz. l /z Water A.oz. 8 Storax av.o Tolu balsam av.o Ether A.OJ Benzoin av.o. 930 THE STANDARD FORMULARY Olibanum • av.oz. 2 Juniper berries av.oz. l /z Reduce the first five ingredients to a coarse powder, free from dust, then thoroughly impregnate it with a solution of the potassium nitrate in the water, and dry the mixture thoroughly. Dis- solve the storax and balsam of tolu in the ether, and evenly and thoroughly saturate the above, after which dry quickly and immediately add the last three ingredients, previously reduced to coarse powder. Fumigating Paper. I. Oil of rose geranium fl.oz. 1 Oil of mace fl.oz. 1 Oil of Ceylon cinnamon. .. .fl.oz. 1 Storax av.oz. 1 Peru balsam gr. 15 Tincture of ambergris m. 75 Alcohol fl.oz. 1 Soak blotting paper in this mixture and then allow it to dry. Cut the paper into squares of about 3 by 3 inches. In using, heat on a warm or moder- ately hot stove so as to vaporize the per- fume. II. Tolu balsam dr. 5 Storax dr. 1 Peru balsam dr. 1 Oil of cassia m. 30 Oil of lavender flowers m. 30 Alcohol fl.oz. 4 Dissolve the balsams in the alcohol and add the oils. Prepare the paper as in the preceding. Fumigating Essence or Tincture. I. Oil of rosemary m. 40 Oil of clove m. 40 Oil of petitgrain m. 40 Oil of lavender flowers m. 60 Oil of bergamot m. 80 Peru balsam m. 80 Acetic ether m. 15 Alcohol fl.oz. 4 Sprinkle a few drops on a hot stove or on a shovelful of live coals. II. Oil of cassia m. 15 Oil of lavender flowers m. 15 Oil of neroli m. 45 Oil of clove m. 75 Oil of lemon m. 75 Oil of bergamot fl.dr. 2^ Musk gr. 1 Storax, liquid m. 75 Peru balsam fl.dr. 2^2 Tincture of benzoin fl.dr. 10 Alcohol fl.dr. 12 Mix, let stand for several days, agi- tating occasionally, and filter. It is to be used like the preceding. Fumigating Vinegar. Fumigating tincture fl.oz. z x A Acetic ether fl.dr. 1^2 Acetic acid fl.dr. 3 Mix, and after standing in a cool place a few days filter. In fumigating sick rooms the vinegar is vaporized either by heating it in a spoon or by pouring it upon a hot iron. QHURCH INCENSE. I. Olibanum av.oz. 7 Benzoin av.oz. 2 Cascarilla av.oz. 1 Reduce all to coarse powder and mix well II. Olibanum av.oz. 8 Benzoin av.oz. 4 Cascarilla av.oz. 2 Potassium nitrate av.oz. 1 Reduce all to coarse powder and mix well. III. Olibanum av.oz. 10 Benzoin av.oz. 2 Storax, dry av.oz. 1 Cascarilla av.oz. iY 2 Potassium nitrate av.oz. y 2 Water fl.oz. 1 Mix the first four ingredients and re- duce to coarse powder, sprinkle with a solution of the potassium nitrate in the water, and allow to dry. CHAPTER II. FACE AND SKIN PREPARATIONS (Cosmetics). Preparations intended mainly or en- tirely for the skin, viz. : Ointments and Creams, Skin Food, Toilet Milks, Toilet Lotions, Toilet Jellies, Camphor Ice, Toilet Lanolin, Almond Paste, Almond Meal, Toilet Powders, Liquid Cosmetics, FACE AND SKIN PREPARATIONS. 931 Face Bleach, Remedies for Blackheads, Freckles, Pimples, Tan, Sunburn, etc. ; Rouge, Grease Paints, Depilatories, Li- quid Soaps, and Shaving Creams and Powders. COLD CREAMS. (Synonyms: Unguentum Leniens, Emolliens or Refrigerans — Ceratum Ga- leni — Creme Celeste.) Preparations known as Cold Creams are mixtures of solid fats like white wax, spermaceti, paraffin wax, petrola- tum, wool- fat, with oils like sweet al- mond, olive, castor, cottonseed, benne, lard, paraffin, etc., and water, rose water, glycerin, distilled extract of witch hazel, etc., the whole being suitably per- fumed. In preparing them the solid fat is first melted at a gentle heat, the oil is added, and then the water, glycerin, etc., previously warmed, is thoroughly incor- porated with the fatty mixture, finally adding the perfume. The incorporation of the water or glycerin is by vigorous and continuous heating in a large mor- tar or similar vessel with a pestle, large spatula or paddle or an egg beater. If the fatty mixture has not been heated too much and the mixture is well beaten, a beautifully white and smooth ointment results in a few min- utes. To greatly facilitate the incorporation of the water or other aqueous liquid, it is now customary to first dissolve in it a small amount of borax. "Cold cream" was originally always made .with sweet almond oil and all pharmacopeias recognizing this prepara- tion specify this oil. However, on ac- count of its costliness, it is frequently replaced by cheaper oils, such as cotton- seed, benne, or lard oil. These oils must be of good quality and light color to produce a white "cold cream." When made with vegetable or animal oil, "cold cream" does not keep well, it soon becoming rancid and granular. The presence of castor oil is said to im- prove its keeping qualities besides mak- 59 ing a smoother cream and one more quickly combined with the water. This oil should also be nearly odorless and colorless. However, in recent times, mineral oil is used in all "cold creams" intended for cosmetic purposes. This oil is known also as liquid petrolatum, paraffin oil, glycoline, and by many trade-marked names. When used for the purpose of making "cold cream" this oil should be entirely odorless and as nearly colorless as it is possible to obtain it. The "cold cream" made with this oil keeps indefinitely without change, is also very cheap, and appears to be entirely satisfactory for cosmetic purposes. The most generally used perfume for "cold cream" is rose in the form of oil of rose. This may be either the natural or synthetic product, the latter being equally as satisfactory as the former and costing much less. Other odorous substances are now also used for per- fuming "cold cream" ; combinations of the various synthetics prove very accept- able. Examples of such combinations are given later on. "Cold cream" as made by different formulas varies in consistency, and vari- ous degrees of hardness or softness may be obtained by altering^ the proportions of wax, oil and water. Any "cold cream" may be made softer by adding more oil, even after the cream has solidified. A harder cream may be obtained by using a smaller amount of oil. Such a preparation receives a name depending on its constitution or aroma. It may be called simply "cold cream": if flavored with bitter almond oil, "almond cold cream"; if it contain cucumber juice, "cucumber cream, pomade, or ointment"; if witch hazel extract, "witch hazel cold cream"; if glycerin, "glycerin cold cream"; if camphor, "camphor cold cream"; lanolin, "lanolin cold cream": salicylic acid, "salicylic or salicylate^ cold cream" ; petrolatum, "petrolatum (or vaselin) cold cream": violet extract or orris, "violet cold cream"; if Peru 932 THE STANDARD FORMULARY balsam, "sultana cold cream" ; boric acid and glycerin, 'boroglycerin cold cream," etc. If tinted slightly with methyl violet and perfumed with lilac, it may appro- priately be called "lilac cold cream." Cucumber cold cream may properly be tinted pale green with chlorophyll. Oth- er colors may suggest themselves. Cold Creams With Vegetable Oils. I. Spermaceti av.oz. 2 White wax av.oz. 2 Sweet almond oil av.oz. 9 Stronger rose water av.oz. 3 Borax gr. 35 Reduce the spermaceti and white wax to fine shavings and melt them at a mod- erate heat, and add the oil and stir, con- tinuing the heat until the mixture is uniform; then gradually add the rose water, previously warmed, and in which the borax has been dissolved, stirring the mixture rapidly and continuously un- til it congeals and becomes of uniform consistence. This is the U. S. P. formula for "ointment of rose water." The presence of borax is sometimes objectionable, as when this ointment is used as a vehicle for metallic salts (e. g., when combined in ointments for the eyes with mercuric oxid), hence the U. S. P. directs that when used for such purposes the borax should be omitted. This ointment is but seldom used for cosmetic purposes. If used as a skin cream it may be aromatized by adding 5 drops of oil of rose to the above quan- tity. Or oil of rose geranium may be used, although this is a coarser odor. Other perfumes or fragrant oils or syn- thetics may be added. II. Spermaceti White wax Castor oil Cottonseed oil Rose water fl.oz. 8 Borax dr. 2 Melt the wax and spermaceti care- fully, add the oils, then the rose water ...av.oz. 4 ...av.oz. 3 . . .av.oz. 4 av.oz. 13 previously warmed and with the borax dissolved in it, and then stir until con- gealed and of a creamy consistence. Various fragrant oils or synthetics may be added. This makes a cheap cold cream. III. Spermaceti av.oz. 2 White wax av.oz. 2 Castor oil fl.oz. 13 Sweet almond oil fl.oz. 6 Z A Rose water fl.oz. 6 Borax gr. 75 Oil of rose drops 16 Prepare like Xos. I or II. This is a variation of Xo. I or the U. S. P. formula. The presence of castor oil is said to result in a product which is more permanent and has a bet- ter appearance. IV. White wax av.oz. 2^2 Lard av.oz. 10 Sweet almond oil fl.oz. 11 Oil of rose drops 20 Oil of bergamot drops 12 Oil of rose geranium drops 12 Borax . . dr. 1 Zinc oxid dr. 5 Water fl.oz. 8 Melt the wax carefully, then add the lard, and when it is melted, incorporate the almond oil. Also warm the water, in it dissolve the borax, rub up w T ith the zinc oxid, and mix this with the fatty liquid, stirring vigorously in a mortar until congealed, finally adding the frag- rant oils. The latter may first be dis- solved in 2 fluidrams of alcohol. The zinc oxid assists in making a pure white cream and probably adds to its cosmetic properties. Cold Creams with Animal Oil. Any of the cold creams made with vegetable or with mineral oil may have the vegetable or mineral oil replaced with lard oil and an equally satisfactory product will be obtained. One of the preceding formulas contain lard and in this respect differ from other formulas. See also the formulas for "cold creams with wool- fat." FACE AND SKIN PREPARATIONS. 933 Cold Creams With Mineral Oil. Mineral oil, thereby meaning liquid petrolatum or paraffin oil, and known in the trade by a great variety of names (glycoline and mineral glycerin are also used), some of which are trade-marked, has largely supplanted sweet almond and the other cheaper vegetable oils. The product is cheap and of good consistency and appearance, and it keeps indefinitely without spoiling. The only objection to it is a slight bluish fluorescence. The mineral oil used should be entirely odor- less and as free from color and fluor- escence as it is possible to obtain it. A "crystal white" oil is said to be now available. Any of the preceding formulas may be used, substituting mineral oil for the vegetable oil. Below are given other formulas which have proved satisfac- tory. V. Alper's formula : White wax av.oz. 5 Paraffin oil av.oz. 20 Water av.oz. 8 Borax gr. 140 Oil of rose geranium drops 15 Oil of rose... drops 20 Dissolve the wax in the oil at a tem- oerature not exceeding 6o° C. In an- other vessel dissolve the borax in the water raised to about the same tem- perature. Pour the aqueous solution in a continuous stream into the fatty liquid, stir the whole for two minutes, and incorporate the volatile oils. VI. Formula of the Canadian Formu- lary: White beeswax av.oz. 4 Spermaceti av.oz. 1 Paraffin oil fl.oz. 16 Distilled water fl.oz. 8 Borax gr. 30 Oil of rose m. 10 Dissolve the borax in the water, melt the wax and spermaceti with the para- ffin oil at a gentle heat, pour the mix- ture into a warm mortar and add while yet hot, the borax solution, previously warmed, with constant trituration, and finally the oil of rose, and continue the trituration until cold. In hot weather the quantity of wax may be increased to 5^2 ounces and the spermaceti to 2 ounces. VII. Oglesby's formula : White wax av.oz. 4 Paraffin oil fl.oz. 20 Water fl.oz. 8 Borax dr. 1 Perfume to suit Melt the wax on a water bath, add the oil, and when melted but not hotter than is comfortable to the finger im- mersed in it, add the water containing the borax previously dissolved in it and brought to the same temperature, mix all at once, not stirring longer than is necessary to mix, then incorporate the perfume, and pour into containers while yet warm. When cool it will have a smooth, glossy surface. VIII. Molyneaux's formula: Paraffin wax av.oz. 4 White wax av.oz. 4^2 Paraffin oil av.oz. i6^4 Distilled water av.oz. 6^2 Sodium perborate gr. 75 Melt the two waxes at a gentle heat, add the oil ; also dissolve the perborate in the water, slightly warming the lat- ter. Then add the aqueous liquid to the melted oil and waxes, in a fine stream, stirring constantly with a pad- dle until the mixture becomes smooth. Finally incorporate the perfume, and pour the cream while still semi-fluid into suitable containers. The product will have a smooth, glossy surface. Cold Creams Containing Petrolatum. IX. Formula of the British Pharma- ceutical Codex: White petrolatum av.oz. 4 White beeswax av.oz. 4 Sweet almond oil fl.oz. 16 Borax dr. 2 T j Rose water fl.oz. 8 Oil of rose m. 15 Melt the wax in the oil and dissolve the borax in the rose water by the aid of a gentle heat. Then add the aqueous liquid gradually to the wax and oil, and stir until the mixture stiffens. Tom' this into a slightly warmed mortar con- taining the petrolatum, mix. add the oil of rose, and stir till cold. 934 THE STANDARD FORMULARY The sweet almond oil may be re- placed by cottonseed or benne oiL X. White wax av.oz. 4^ Spermaceti av.oz. 2J/2 White petrolatum av.oz. 18 Rose water ^.. fl.oz. 6 Borax dr. 3 Oil of rose geranium m. 15 Melt the wax, spermaceti and petro- latum together at a gentle heat, strain into a warmed wide-mouthed bottle, then add the rose water, previously warmed and containing the borax dis- solved in it, also the oil of rose gera- nium, and agitate until well mixed and congealed. XI. White petrolatum av.oz. White wax av.oz. Paraffin oil, white. fl.oz. Rose water fl.oz. Borax dr. Cumarin gr. Oil of rose m. 30 Heliotropin gr. 15 Oil of bergamot drops 5 Oil of orris, concrete gr. 1 Prepare like Xos. 1, 2, 3 or 4. Cold Creams Containing Wool-Fat. The hydrous wool-fat is to be used in these creams and this should be a first-class product as free as possible from odor and color. The cold cream obtained will, of course, not be white but cream-colored. The presence of wool-fat is said to make the cream more readily absorbed by the skin. It is also added to cold creams containing paraffin or petrolatum to counteract the non-absorbent properties of the latter. XII. White wax Spermaceti Sweet almond oil Wool-fat, hydrous.. Rose water Borax dr. 1 Perfume to suit Melt the wax and spermaceti, at a gentle heat, add the oil and wool- fat, continuing the heat until the latter is melted, then incorporating the rose water, previously warmed and in which . .av.oz. 2 . .av.oz. 2 . . .fl.oz. 12 ...fl.oz. 5 . . .fl.oz. 10 the borax has been dissolved; finally add any desired perfume. The proportions of oil and wool-fat may be varied, and the almond oil may be replaced by cottonseed or benne oil. XIII. Scoville's formula : Paraffin wax av.oz. 4 Paraffin oil fl.oz. 12 Wool-fat, hydrous av.oz. 8 Rose water fl.oz. 8 Borax dr. 1 Melt the wax at a gentle heat, add the oil and wool-fat and then incor- porate the water in which the borax has previously been dissolved. Cold Creams Without Water. A true "cold cream" contains water but nevertheless formulas have been of- fered for such preparations without water to avoid the troublesome incor- poration of the latter. The following is one of them : XIV. Paraffin wax av.oz. 6 White wax av.oz. 3 Paraffin oil, colorless fl.oz. 24 Perfume to suit Melt the two waxes on a water bath, remove from the source of heat, incor- porate the oil, stirring briskly till con- gealed, then incorporate any desired per- fume. The following formula is also excel- lent: XV. White petrolatum av.oz. i2 l / 2 Paraffin wax av.oz. ij^ Tincture of benzoin fl.dr. 4 Glycerin fl.dr. 6 Zinc oxid dr. 6 Perfume to suit Melt the wax at a gentle heat, add the petrolatum, rub the zinc oxid to a smooth paste with the glycerin, and add this and the tincure to the melted mix- ture, and stir the whole until congealed. Finally add any desired perfume. Cold Creams, Greaseless or Non- Greasy. (Absorbent, Vanishing or Disappear- ing Cream — Stearin Jelly — Stearin Cold Cream.) FACE AND SKIN PREPARATIONS. 935 This is a novelty of recent introduc- tion which is not strictly a "cold cream" but is a stearin soap containing consid- erable water and usually some glycerin. The stearic acid used for this purpose is what is commercially known as stearin, a hard, white waxy-like solid of an odor resembling tallow. A fairly good grade of stearin should be used; a chemically pure article is not neces- sary and is too expensive, a cheap grade of a rancid odor is, however, unfit for use. The stearin or stearic acid is heat- ed on a water bath (higher tempera- tures decompose it) with distilled water and glycerin containing an alkaline sub- stance in solution such as borax or potassium or sodium carbonate, when the stearin will combine with the alkali and water to form a real soft solution of stearin soap. The heating requires sev- eral hours, so that distilled water must be added from time to time to the mix- ture to make up for that lost by evapor- ation. These creams should be kept in well- closed jars or dispensed in collapsible tubes to prevent evaporation of the water and drying out of the prepara- tion. A certain amount of glycerin is necessary to prevent this drying-out property. A mucilage in place of a portion of the water such as mucilage of quince seed, agar-agar or tragacanth, or glycerite of starch in place of gly- cerin, will also obviate the drying-out property. When rubbed on the skin, a cream of this kind appears to be entirely absorbed, hence the names "absorbent, vanishing, or disappearing cream" which are ap- plied to it. This property would also make it serviceable as a "skin food," al- though as a real skin food, a lanolin cream is the ideal article. These creams may be perfumed in any desired manner. XVI. Cooban's formula : Stearic acid (stearin) av.oz. 2 Sodium carbonate, pure. . .av.oz. i l /i Borax, powder av.oz. Y\ Glycerin fl.oz. 4 Water fl.oz. 32 Oil of ylang ylang drops 80 Oil of rose drops 20 Heliotropin gr. 20 Alcohol fl.oz. 4 Mix all the ingredients together and heat on a water bath until effervescence ceases. Remove the mixture from the source of heat and stir at intervals until it begins to stiffen, then incorporate the aromatic substances dissolved in the al- cohol. Beat this up with' a paddle or an egg beater. It may be made more fluffy and creamy by reheating and beating it up again. Several modifications may be made in this formula. Two av. ounces of cocoa butter may be added during the heating but the product will be slightly greasy. The glycerin may be replaced by glycerite of starch. Also half of the water may be replaced by mucilage of tragacanth, quince seed or agar agar. The mucilage of tragacanth may be made according to the U. S. P. Mucilage of quince seed may be made of the proportion of 1 or 2 drams to the pint of water. Mucilage of agar agar may be made by heating 75 grains of agar agar with 4 fluidounces of water until dissolved, straining forcibly through cheese-cloth, and adding this while still warm to the stearin solution. Of course the perfume may also be varied. XVII. Stanislaus' formula : Stearic acid av.oz. 1 1 / 2 Cocoa butter av.oz. l /i Sodium carbonate, pure. .. .av.oz. 1 Borax, powder av.oz. x /\ Glycerin fl.oz. V/\ Water fl.oz. 20 Mucilage of tragacanth fl.oz. 5 Terpineol m. 45 Oil of bitter almond drops 2 Oil of rose drops IS Alcohol fl.oz. i t j Dissolve the salts in the water, and add this solution with the glycerin and mucilage to cocoa butter and stearic acid contained in a vessel on a water bath. Heat the whole together until efferves- cence ceases, allow to cool, then add the perfumes dissolved in the alcohol, and [)36 THE STANDARD FORMULARY beat with an egg beater until it stiffens. Reapply heat and beat again until it be- comes fluffy and creamy. XVIII. Stearic acid av.oz. 4 Sodium carbonate av.oz. J / 2 Glycerin fl.dr. 4 Water fl.oz. 16 Distilled ext. witch hazel. . .fl.oz. 20 To the glycerin contained in a large evaporating dish add the sodium car- bonate previously dissolved in the water. Add the stearic acid and heat the mix- ture on a water bath until no more vapors of carbon dioxid are evolved and a clear solution results. Keep this near the boiling point for at least an hour, stirring frequently, and making up for loss through evaporation by the addition of more water, being careful not to add too much. Now add the witch hazel extract, transfer the whole to a hot mortar, and beat with an egg beater until it becomes of the proper consistency. Allow to stand for 12 hours, stir well and transfer to jars that may be well closed, wide-mouthed bot- tles, or collapsible tubes. Almond Cold Cream (Almond Cream). This may be prepared like any of the preceding "cold creams" but substituting oil of bitter almond for oil of rose or other perfumes, or the following may be used: XIX. Spermaoeti av.oz. 3 White wax av.oz. 3 Sweet almond oil fl.oz. 16 Water fl.oz. 8 Borax . dr. 1 Cumarin gr. 1 Oil of bergamot drops 20 Oil of bitter almond drops 10 Oil of rose or rose gera- nium drops 6 Tincture of ambergris. .. .drops 5 The cumarin and tincture of amber- gris may be omitted, also more bitter almond oil may be used. Benzaldehyde may replace the latter oil. Cottonseed or benne oil may also replace the sweet almond oil. Benzoinated Cold Cream. Use any of the formulas of "cold cream" but adding tincture of benzoin to the perfumes or this tincture may en- tirely replace the other aromatic sab- stances. Or use the following modified from the. French Codex: XX. White wax av.oz. 2]A Spermaceti av.oz. 5 Sweet almond oil fl.oz. 17 Rose water fl.oz. 5 Tincture of benzoin fl.oz. \ l / 2 Mix in the usual manner for "cold creams." Boroglycerin Cold Cream. Any of the preceding formulas for "cold cream" may be used or those for "glycerin cold cream" but substituting boroglycerin or solution of boroglyceride for a portion of the water or for the glycerin, or use the following: XXI. Boric acid, powder dr. 2 Glycerin fl.oz. 3 Water fl.oz. 4 Wool-fat, hydrous av.oz. 3 Paraffin wax av.oz. 4 Paraffin oil fl.oz. 16 Oil of rose drops 10 Oil of bergamot drops 10 Warm together the first three ingredi- ents until solution is effected. Melt to- gether the lanolin and petrolatum, add the oil, incorporate the boroglycerin so- lution by rapid and constant stirring, then add the oils, and mix again. Camphor Cold Cream. (Camphorated Cold Cream.) This may be made by using any of the formulas for "cold cream" but dis- solving a small amount of camphor gum in the oil or wax by the aid of a gentle heat before adding the other ingredients, or the following formulas may be used : XXII. Mme. Qui Vive's formula: Spermaceti av.oz. 2 White wax av.oz. 2 Sweet almond oil fl.oz. 13 Camphor av.oz. 1 Distilled water fl.oz. 6 Borax dr. 1 FACE AND SKIN Oil or rose drops 16 Oil of rose geranium drops 4 Oil of ylang ylang drops 4 Tincture of musk drops 8 Tincture of civet drops 8 Prepare like \o. II. XXIII. Camphor av.oz. 2 Spermaceti av.oz. 2 White wax av.oz. 4 Sweet almond oil fl.oz. 20 Rose water fl.oz. 4' Oil of rose drops 20 Prepare like the preceding. Cotton- seed or benne oil may replace the sweet almond oil. Cocoa Butter Cold Cream (Theo- broma Cold Cream). XXIV. Cocoa butter av.oz. l% White wax av.oz. 3 Paraffin wax av.oz. 3 Paraffin oil, colorless av.oz. 16 Water fl.oz. 6 Borax dr. 2 Perfume to suit Melt the waxes and cocoa butter at a gentle heat, add the oil, then ^cor- porate the water, previously warmed and containing in solution the borax, stir until congealed, and add the per- fume. Spermaceti may replace the paraffin wax, and cottonseed, sweet almond or benne oil the mineral oil but the prod- uct will not keep well. The cocoa butter may be increased if desired. Cucumber Cold Cream (Cucumber Cream). Any of the formulas for "cold cream" lay be used, but substituting cucumber iuice for a portion of the water. The Following formulas may also be used. Cucumber cream is usually supposed to lave a pale green tint. This color may )e imparted by means of oil-soluble :hlorophyll. :xv. Wool-fat, hydrous av.oz. 8 Sweet almond oil av.oz. 2^ Cucumber juice, freshly ex- pressed fl.oz. 16 Add any desired perfume, also tint nth. chlorophyll as described above. PREPARATIONS. 937 XXVI. . Spermaceti av.oz. 3 White wax \ av.oz. 3 Castor oil av.oz. 4 Cottonseed oil av.oz. 12 Cucumber juice fl.oz. 10 Borax av.oz. l / 2 Benzoic acid gr. 30 Melt the two waxes at a gentle heat, add the acid and oils, then the juice, previously slightly warmed and contain- ing the borax in solution, and beat vig- orously until well mixed and congealed. The juice should be freshly expressed from green cucumbers and strained through cotton. Glycerin Cold Cream. Any of the formulas for "cold cream" may be used but substituting glycerin for all or a portion of the water, or the following will prove satisfactory : XXVII. Spermaceti . av.oz. 6 White wax av.oz. 2 Sweet almond oil fl.oz. 16 Borax dr. 4 Glycerin fl.oz. 6 Orange flower water fl.oz. 2 Oil of neroli drops 10 Oil of rose drops 6 Melt the wax, spermaceti, and almond oil together at a gentle heat, dissolve the borax in the orange water and gly- cerin previously mixed; pour the solu- tion, a little at a time, into the melted mixture, stirring the preparation with- out ceasing until all the solution has been fully incorporated, and a homogen- eous product results ; finally add the es- sential oils. The almond oil may be replaced by cottonseed, benne or paraffin oil, and other" perfumes may be used, such as rose water for the orange flower water. Glycerin Balsam, which see, is sim- ilar to the above. A variation of the above is to rub up the glycerin with powdered traga- canth to a smooth paste and incorporat- ing this with any regulation "cold cream." Lanolin Cold Cream (Lanolin Cream). See Cold Creams with Wool-Fat. 938 THE STANDARD FORMULARY Lemon Cold Cream (Lemon Cream). This may be prepared by substituting the juice of lemons for a portion of the water in any of the preceding "cold creams." However, the product is not permanent unless the "cold cream" be made with paraffin oil or else contains considerable petrolatum. Mentholated Cold Cream. This may be prepared like the cam- phorated cold creams but replacing the camphor containing in the latter with one-fourth as much menthol. Oxygenated or Peroxid Cold Cream. Any "cold cream" may be converted into an oxygenated or peroxid cream by replacing a portion of the water with hydrogen peroxid, or by using 2 drams of sodium perborate or zinc peroxide to the pound of cream instead of borax. These creams are supposed to act as skin bleaches. See also the third for- mula under Face Bleaches. Rose Cold Cream. Rose cold cream may be prepared from any of the "cold creams" by tint- ing a rose color by means of solution of carmine, and also preferably impart- ing to it a strong odor by means of natural or synthetic oil of rose. Salicylated of Salicylic Cold Cream. XXVIII. White wax av.oz. 2 Spermaceti av.oz. 2 Sweet almond or cottonseed oil fl.oz. 12 Distilled water fl.oz. 2 Glycerin fl.oz. 2 Salicylic acid gr. oo Oil of rose drops 5 Oil of neroli drops 5 Oil of bergamot drops 5 Oil of wintergreen drops 3 Prepare in the usual manner for making cold cream, but add the sali- cylic acid last, previously trituating it to a smooth paste with the glycerin. Strawberry Cold Cream (Strawberry Cream). XXIX. Mme. Qui Vive's formula : White wax av.oz. 2 Spermaceti av.oz. 2 Sweet almond oil fl.oz. 10 Strawberry juice fl.oz. 3 Tincture of benzoin drops 12 Prepare like the other "cold creams." The strawberry juice should be freshly expressed from ripe berries. It is probable that, owing to the acid nature of the juice, this cream does not keep well. Sultana Cold Cream. XXX. Spermaceti av.oz. 1 White wax av.oz. 1 Sweet almond oil fl.oz. 16 Cocoa butter av.oz. 16 Orange flower water fl.oz. 4 Peru balsam av.oz. 1 Melt the wax and spermaceti, add the cocoa butter, melt again, add the oil, and then incorporate the orange flowei water and balsam. Theatrical Cold Cream. By this term is meant any moderately soft "cold cream" that can be sold at 50 cents per pound. Practically all of the foregoing formulas that are made with cottonseed, benne, lard or paraffin oil and do not contain much cocoa but- ter may be sold profitably at this price. If they are lacking in softness, more oil may be added. Watch Hazel Cold Cream. XXXI. White petrolatum av.oz. 18 White wax av.oz. 3 Spermaceti av.oz. 3 Distilled ext. of witch hazel. fl.oz. 6 Melt the first three ingredients to- gether, allow to cool to some extent, then add the witch hazel extract and stir. When nearly cold add any de- sired perfume and stir vigorously. PERFUMES FOR COLD CREAM. These are special combinations of odorous substances that may be used in place of those mentioned in the pre- ceding formulas : I. Cumarin gr. 1 Oil of rose drops 30 Oil of neroli drops 10 Oil of rose geranium drops 7 Oil of ylang ylang drops 3 Oil of orris _ drop 1 Tincture of ambergris drops 10 FACE AND SKIN PREPARATIONS. 939 n. Cumarin gr. i Heliotropin gr. 15 Oil of orris, concrete gr. 1 Oil of bergamot drops 5 Oil of rose m. 30 III. Terpineol fl.dr. 1 Oil of rose geranium m. 15 Heliotropin gr. 10 CREME DUCHESSE, Mme. Qui Vive's. Benzoinated tallow av.oz. 12 Sweet almond oil av.oz. 4 Glycerin fl.oz. 1 Rose water fl.oz. 1 Oil of rose geranium drops 80 Prepare this like the "cold creams." The benzoinated tallow may be made like benzoinated lard. CREME MARQUISE, Mme. Qui Vive's. White wax . . • av.oz. 1 Spermaceti av.oz. 10 Sweet almond oil fl.oz. 10 Rose water fl.oz. 6 Oil of rose drops 4 Mix in the usual way for preparing "cold creams." CREME DE LA VIOLETTES. Mme. Qui Vive's formula : White wax av.oz. 2 Spermaceti av.oz. 2 Sweet almond oil fl.oz. 10 Rose water fl.oz. 3 Borax gr. 20 Violet extract fl.dr. 1 Prepare like the "cold creams." EMOLLIENT CREAMS. The following is quite different from the "cold creams" and may appeal to some as an excellent combination : Precipitated sulfur av.oz. 4 Zinc oxid av.oz. 4 Wool-fat, hydrous av.oz. 4 Sweet almond oil. av.oz. 2 Violet extract fl.dr. 2 Make into an ointment in the usual manner, taking particular precautions to rub the sulfur and zinc oxid thor- oughly smooth. The mixture may be tinted red with alkanet, the latter being heated with the oil to extract the color- ing matter. Other perfume may also be used instead of the violet extract. This is recommended as a skin cream instead of "cold cream." It possesses some medicinal properties and is said to be useful for removing tan and freckles. GLYCERIIT BALSAM, Mme. Qui Vive's. White wax av.oz. 1 Spermaceti av.oz. 2 Sweet almond oil av.oz. 9 Glycerin av.oz. 3 Oil of rose geranium drops 16 Melt the waxes, then add the oil, re- move from the fire, and heat in the glycerin, stirring briskly until congealed. This is similar to "glycerin cold cream," which see. CUCUMBER JUICE OR ESSENCE. Take cucumbers in the green state, wash them thoroughly, then slice them with the skin on, into small fragments, place in an earthen or porcelain dish, pour upon them hot water to cover and let simmer for half an hour or more, being careful that the heat is not too high or the water too low so as to scorch. Then strain through a colander or muslin, and add to every pint of the juice four fluidounces of alcohol. Let stand over night and filter to remove precipitated albuminous matter. The juice can also be preserved some length of time without the addition of alcohol, by the addition of thirty grains of salicylic acid dissolved in half an ounce of alcohol, or one dram of boric acid and sixty grains of borax dissolved in a pint of the juice, or the addition of one fluidram of solution of formalde- hyde to one pint of the juice. This juice or essence is suitable for the preparation of cucumber cream, ointment, salve, or milk, and is added in a similar manner as is rose water in preparing "cold cream." CUCUMBER OINTMENT OR POM- ADE. See also Cucumber Cold Cream. I. Melt together 11 av. ounces of lard and 7 av. ounces of veal suet, the suet 940 THE STANDARD FORMULARY first having been rendered, in a water bath. To the fat, strained into a jar of the capacity of one gallon, when it begins to thicken add one-third of the juice obtained, by grating and express- ing 3 av. pounds of green cucumbers and beat the mixture with a spatula until all of the odor of the cucumber has been absorbed by the fat, which will re- quire several hours. The watery fluid should then be rejected and the remain- ing juice added in two consecutive por- tions, incorporated in the previous man- ner and the watery liquid again rejected. The fat should then be heated in a closed vessel on a water bath for one hour, the albuminous coagulum should be skimmed off, the watery matter should be removed on cooling, the oint- ment should again be melted and then strained. Before use, this fat should be trituated with a little rose water until it is of a creamy character. This formula was devised many years ago by Prof. Procter. On account of its complicated nature, the same author- ity devised a somewhat simpler method of procedure, as follows : Cucumbers av.lb. I© Sweet almond oil av.lb. I Grate the cucumbers without paring, on a tinned grater, express the juice, and strain it through a close-woven cloth. Put half the juice into a gallon bottle, add the oil, cork the bottle, and agitate the mixture at short intervals during several hours, let the oil rise to the surface, decant the exhausted juice and replace it by the remainder of the juice, again agitate freely and re- peatedly, allowing 2d hours to elapse be- fore setting it aside to separate. Then decant the exhausted juice and throw it away. Finally separate the oily layer as much as possible from water, and filter it through a pleated filter which has previously been dipped in sweet al- mond oil and allowed to drain. A clear, bright, oily filtrate is obtained except towards the last when some water be- gins to come through. All moisture must be separated to prevent change in the oil which may be known as "cu- cumber oil." It has a decided odor of cucumber, and is used for preparing cucumber ointment according to for- mulas II and III. II. White wax av.oz. i Cucumber oil av.oz. 4 Mutton suet av.oz. 8 Melt the wax and suet at a gentle heat, add the oil, and stir until it thickens. This is said to be nearly white, to be perfectly smooth and homogeneous, and to have an agreeable odor of cucum- bers. III. White wax av.oz. I Spermaceti av.oz. 4 Cucumber oil av.oz. 8 Sweet almond oil av.oz. 12 Prepare like No. II. It is softer than the preceding. MASSAGE CREAMS, Casein or Rolling. Massage creams are of two varieties, those that "roll up" on the skin and the greasy kind. The latter will be treated in the next article. The former is made with casein as a basis. This is mixed with glycerin, oil, or wool-fat to give it softness, with an antiseptic agent to preserve it, and is usually colored pink. The glycerin also prevents drying out. The casein for this purpose may be purchased in the dr* condition in the market, or it may be precipitated from milk by means of an acid, alum or ren- net. Preferably skimmed milk should be used or the fatty matter shoul 1 first be separated. The presence of any but- ter fat in the product will induce speedy rancidity. The finished cream should be dispensed in well-closed jars. This cream is used mostly to smooth out wrinkles and to clear the skin by removing blackheads. I. Cooban's formula : Skimmed milk gall. 1 Hydrochloric acid fl.oz. 1 Boric acid, powder av.oz. 1 FACE AND SKIN PREPARATIONS. 941 Diluted alcohol fl.oz. I Oil of bergamot drops 20 Oil of rose geranium drops 30 Sweet almond oil fl.dr. 4 Solution of carmine, water, each sufficient To the milk add one gallon of water hot enough to raise the temperature of the mixture to about 8o° F. Mix the hydrochloric acid with one pint of water and add this to the diluted milk slowly and with constant stirring. Allow the liquid to stand for an hour, collect the precipitate on cheese-cloth, allow it to drain, return it to the vessel and add 2 gallons of water. Agitate the liquid thoroughly, breaking up the masses of coagulum, and again drain as before. Repeat this washing and draining until the casein is free from acid and whey. Finally rub up the casein in a mortar with boric acid until well mixed, again transfer to a cheese-cloth bag and allow to hang suspended for 36 to 48 hours, squeezing the bag occasionally, until the casein is quite dry. Transfer the dried and granular casein to a mortar, tritur- ate it till smooth, adding the diluted alcohol to facilitate the process. When well rubbed out, incorporate the sweet almond and aromatic oils and tint suffi- ciently with carmine solution. Then add water enough to form a soft paste and triturate together until well mixed. It is said a perfectly smooth product will not be obtained until it is ground in a paint mill. It must be bottled at once to prevent drying out in suitable jars, ir it may be put into collapsible tubes. II. Dr. M. E. Doyle's formula : Milk, preferably skimmed. . .gall. I Magnesium sulfate av.oz. 13 Alum dr. g l / 2 Water sufficient Heat the milk to about 120 F., add the magnesium sulfate made into a sat- uated solution in water, set the mixture aside for about an hour, again heat to 130 F., add the alum previously dis- solved in hot water, and continue the heat a little longer until the casein is entirely separated, but not allowing the temperature to rise above 145 F. Wash this, like the precipitate in the preceding formula, in several changes of water, and then hang up in a cloth to drain until dry. Then take the fol- lowing : Casein, precipitated as above av.oz. 20 Boric acid, powder av.oz. 4 Cocoa butter .- . av.oz. 2 Solution of carmine, spirit of bitter almond, each ... sufficient Rub up the casein in a mortar, add the cocoa butter, previously melted, con- tinuing trituration until smooth. Also add carmine solution to color pink and enough of the spirit to impart suitable odor. III. Harley's formula: Skimmed milk gall. 1 Alum, powder av.oz. 3 Borax, powder av.oz. 3 Boric acid, powder av.oz. 2 Carbolic acid, 90% drops 25 Oils of rose geranium and bitter almond, each sufficient Water, solution of carmine, each sufficient Heat the milk to 130 F. ; dissolve the alum in 4 fluidounces of water and heat to the same temperature; also dissolve the borax and boric acid in 10 fluid- ounces of water and heat this to the same temperature. Mix the milk and the second solution, then add the alum solution (all being at about 130 F.). After the milk has curdled, strain it, and if not clear, add more alum solu- tion to it, enough to clear it. Collect the casein, incorporate it with the car- bolic acid, enough of the oils to im- part a suitable odor, and a sufficient amount of carmine to tint it properly. IV. Morgan's formula: Skimmed milk gall. I Tartaric acid av.oz. 4' Zinc oxid av.oz. 1 Borax, powder av.oz. J a Glycerin fl.oz. 2 Water fl.oz. 32 Solution of carmine, perfume. each sufficient Dissolve the acid in the water and add to the milk, collect the precipitate 942 THE STANDARD FORMULARY and drain it. Rub the zinc oxid to a smooth paste with the glycerin, incor- porate the casein, borax, enough solution of carmine to tint properly, and a suffi- cient amount of any desired perfume. V. Casein, dried av.oz. 8 Borax, powder av.oz. i Wool-fat, hydrous av.oz. 6 Oil of bergamot dr. 2 Oil of bitter almond m. 30 Glvcerin fl.oz. 4 Water fl.oz. 16 Solution of carmine sufficient Mix the casein, borax, glycerin and water and heat on a water bath until a uniformly smooth and jelly-like mass is obtained, then transfer to a mortar, add the wool- fat, triturate till well mixed and smooth, incorporate the oils, and finally tint sufficiently with 'the car- mine solution. MASSAGE CREAMS, Fatty. Different fatty or oily substances are used for purposes of massage, such as olive, sweet almond, or cocoanut oil, and professional masseurs have various favorite mixtures of their own. All the "cold creams," except the non-greasy kind, may be used for this purpose, in fact most of the massage creams and "skin foods" are in reality "cold creams." These fatty massage creams are extolled as skin foods; some of the fatty matter is supposed to be ab- sorbed, making the tissues more plum", and the accompanying massage helps to smooth out wrinkles, soften the skin, and fill out the cheeks, neck, and bust. The previously mentioned casein mas- sage creams are really not skin foods but act only as cleansers. I. White wax av.oz. 4 Wool-fat, hydrous av.oz. 2 Paraffin oil av.oz. 16 Rose water fl.oz. 6 Rorax. powder dr. 2 Perfume to suit Melt the wax, add the wool-fat and oil, dissolve the borax in the rose water by the aid of a gentle heat, and stir the whole together, beating it until con- gealed. Finally add perfume of any desired kind. If there is objection to the mineral oil, it may be replaced by sweet almond, cottonseed or benne oil. II. Wool-fat, hydrous av.oz. 4 Benzoinated lard av.oz. 4 Sweet almond oil av.oz. 4 Glycerin av.oz. 2 Rose of orange flower water. fl.oz. 2 Perfume to suit MASSAGE EMOLLIENT. The following liquid has been sug- gested to use instead of massage cream : Sweet almond oil fl.oz. 12 Tolu balsam dr. 2 Benzoin dr. 2 Oil of bitter almond fl.dr. 1 Oil of lemon drops 10 Oil of bergamot drops 10 Warm the sweet almond oil with the tolu and benzoin and keep warm for several hours, then allow to cool, strain, and add the other oils. SKIN FOOD. Preparations sailing under this name are usually "cold creams" or fatty mas- sage creams or other bland ointments suitably perfumed and sometimes tinted. Fat forms the basis and gives them their hygienic effect as it imparts fullness and softness to the skin. When applied, these preparations are to be rubbed into the skin abundantly, and the friction as- sists the absorbed fat in developing the muscles. Any of the cold creams may be dispensed under the name of "skin food" or any of the subjoined may be used. The so-called "greaseless cold. cream," which see, is recommended as a skin food because it dries on the skin but apparently it "rubs in." White petrolatum av.oz. 16 Paraffin wax av.oz. 2 Wool-fat, hydrous avoz. 4 Water fl.oz. 6 Oil of rose geranium drops 40 Melt the paraffin, add the petrolatum and wool- fat, pour into a warm mortar with constant stirring, incorporate the water and perfume. FACE AND SKIN PREPARATIONS. 943 If the preparation is to be tinted red use alkanet root, and an amber colored petrolatum may be employed instead of the white. Orange Flower Skin Food (jYEme. Qui Vive's)— (Cuticle Cream). White wax av.oz. 2 Spermaceti av.oz. 2 Cocoanut oil av.oz. 4 Wool-fat, hydrous av.oz. 4 Sweet almond oil fl.oz. 8 Orange flower water fl.oz. 4 Tincture of benzoin drops 12 Melt the wax and spermaceti at a gen- tle heat, add the oils and wool-fat, con- tinue the heat until all are melted, then add the water and tincture, and stir vigorously until congealed and of a creamy consistence. BUST DEVELOPERS. These are of the same type as the "skin foods," in fact the latter are al- ways mentioned as bust developers. As in the case of other portions of the body, the bust is developed or enlarged when vigorously and frequently mas- saged with the assistance of a suitable fatty body. The directions given with an advertised bust developer were as follows : Sponge each breast for 10 minutes with cold water ; follow this sponging with brisk friction with a coarse towel for 5 minutes. After the breast is thor- oughly dried and the skin is in a glow, rub the unction well into the skin. All motions should be made firmly but with- out sufficient force to bruise the ten- der tissues or abrade the skin. The motions are best alternated from circles beginning at the base of the gland and decreasing in size until the nipple is reached, to straight stroking lines con- verging from the base of the breast to the nipple. Repeat this treatment twice daily. The following is what is called Ben- nett's Breast Developer: I. Castor oil fl.oz. 4 Glycerin fl.oz. 4 Alcohol fl.oz. 8 Peru balsam dr. 1 Oil of bergamot fl.dr. 1 Oil of lavender flowers m. 30 Oil of rosemary m. 30 This is to be rubbed thoroughly into the breasts at night. The following remedy is for internal use and has been highly recommended under the name Vaucaire Remedy : II. Fluid extract of goat's rue (Galega vera) fl.dr. 2 x / 2 Tincture of fennel fl.dr. 2^2 Calcium lactophosphate dr. 2^ Simple syrup, to make fl.oz. 16 The directions are "A soupspoonful before meals and upon wing to bed." The efficacy of the preparation is mainly in the presumed galactagogue properties of the goat's rue. FACE OR TOILET CREAMS (Non- Greasy Skin Creams). These preparations are mucilaginous in character, consisting of tragacanth, quince seed, linseed, Irish moss or agar- agar mucilage combined with water, al- cohol, glycerin, borax, or boric acid, and sometimes other ingredients. The for- mulas do not specify coloring matter, but the preparations may be tinted any desired color; red, for example, by means of solution of carmine; violet by means of violet aniline, etc. These creams may be dispensed in moderately wide-mouthed bottles or in collapsible tubes. Such preparations may be dispensed under the names "face cream," "toilet cream," Pooling cream," "skin cream," "cosmetic cream," "glycerin cream." "chappine cream," fragrant cream," or similar titles. If containing menthol, the title "menthol cream" may be used; if containing camphor, "camphor cream"; if containing calendula. "calendula cream," etc. Other titles which are used are "cream of roses," "cream of lilacs." "calendula and glycerin lotion," etc. See also "Creams Containing Al- mond." These preparations are useful in sum- mertime to remove as well as to prevent 944 THE STANDARD FORMULARY tan or sunburn, and in winter to cure and prevent chapped hands, cracked lips and other roughnesses of the skin. La- dies will also find them useful to apply to the face before using a complexion powder, and gentlemen will find it of advantage to use them on the face after shaving. Toilet Creams Containing Traga- canth. Either the whole gum or powdered tragacanth may be used for making a toilet cream; the powder is very much more convenient although current for- mulas generally mention the whole gum. The advantage in using the powder is that the preparation may be finished at once while the whole gum requires a lengthy preliminary maceration to soften it. The softening may be accelerated by using the water warm or hot and by frequent beating with a paddle or tritu- ration in a mortar with a nestle. After the gum has softened thoroughly the other ingredients may be added and the whole squeezed through cheese-cloth or muslin, preferably the former, as the texture of the muslin is too dense for this purpose. Or the mixture may be very conveniently run through a hand flour sifter. The appearance of a cream made with powdered tragacanth varies according as a commercial or a pure powder is used. Either will make a satisfactory prepara- tion but the pure powder will make a more translucent and cleaner looking product. A very satisfactory way of making a cream with powder of traga- canth is to agitate the powder in a bottle with the alcohol or alcoholic liquid, if such is present in the mixture, until the mixture is free from lumps, then add the water or aqueous liquid, all at once, and shake again until well mixed, then incorporate the other ingredients. If the mixing has been properly done, no straining is required, but if any lumps are present, these may be separated by straining through cheese-cloth or, more quickly and satisfactorily, through a small wire tea or coffee strainer. The powder may also be triturated in a mor- tar with glycerin to a smooth paste, and the other ingredients incorporated by continued trituration. Any desired perfume rriay be added, such as mixtures of various aromatic volatile oils or synthetic perfumes. The mixtures mentioned under "Perfumes for Cold Cream" may be used. These creams may be tinted if de- sired. I. Tragacanth, whole dr. 2 Boric acid av.oz. Vz Glycerin fl.oz. 4 Alcohol fl.oz. 4 Water ; fl.oz. 24 Perfume, to suit. Dissolve the acid in the water by the aid of heat, add the gum, macerate un- til the latter is softened, stirring vigor- ously from time to time, then add the other ingredients, and strain the whole forcibly through cheese-cloth. Finally add any desired perfume. II. Tragacanth, powder dr. 4 Alcohol fl.oz. 4 Glycerin fl.oz. 8 Water fl.oz. 20 Perfume, to suit. Shake the powder with the alcohol in a bottle until the mixture is free from lumps, then add the water, all at once, shake until thoroughly well mixed, and then incorporate the glycerin and per- fume. Finally strain through cheese- cloth or a small strainer. III. Tragacanth, powder dr. 2 Borax dr. 2 Glycerin fl.oz. 4 Water fl.oz. 28 Perfume, to suit. Triturate the gum with the glycerin to a smooth paste, dissolve the borax in the water, filter the solution, and incorporate this with the previously prepared paste. Finally add the perfume. IV. Tragacanth, whole dr. 2 Starch dr. 2 Boric acid gr. 30 FACE AND SKIN PREPARATIONS. 945 Carbolic acid m. 25 Oil of rose drops 10 Oil of lavender flowers. . .drops 20 White rose extract fl.dr. 4 Tincture of benzoin fl.dr. 1 Glycerin fl.oz. 3 Alcohol fl.oz. 6 Water, to make fl.oz. 32 Dissolve the boric acid in 16 fluid- ounces of water, add the tragacanth, macerate until thoroughly softened, stir- ring vigorously from time to time, and strain forcibly through cheese-cloth or run through a small flour sifter. Also neat the glycerin and starch together carefully, with constant stirring, until a smooth jelly is obtained. To this grad- ually add the tragacanth, incorporating thoroughly together. Now add a mix- ture of the carbolic acid, oils, extract and alcohol, mix well, and finally add the water. If necessary, strain again through the cheese-cloth or flour sifter. Toilet Creams Containing Quince Seed. Quince seed in the uncrushed form yields considerable mucilage to water and hence it makes a satisfactory toilet cream. To make such a cream with quince seed, the latter is simply macer- ated in water, the liquid being stirred vigorously from time to time. A cleaner looking product is obtained if the quince seed is first washed on a sieve with run- ning water to remove adherent dirt and dust. It is best not to add boric acid or borax to the liquid during maceration of the seed as these substances appear to hinder the solution of the gummy mat- ter. If a milky white preparation is de- sired, it may be obtained by adding a small amount of tincture of benzoin, about 1 ounce to the gallon. Any kind of desired perfume, such as an "extract," aromatic oil, or synthetic perfume, may be added to the cream. V. Quince seed av.oz. Y\ Glycerin fl.oz. 4 Borax, powder dr. 2^ Water fl.oz. 27 Cologne water fl.oz. 2 Heat the water to boiling, add the seed, macerate for about 4 hours, stir- ring frequently, then strain the liquid, add the glycerin and borax, dissolve the latter by the aid of a gentle heat, allow to cool and finally incorporate the co- logne water. Other perfume or aromatic oils may be used. The water may also be used cold but a longer maceration of the seeds will be required. VI. Quince seed dr. 4 Borax dr. i l / 2 Boric acid dr. V/ 2 Glycerin fl.oz. 4 Alcohol fl.oz. 4 Water fl.oz. 24 Perfume, to suit. Heat 20 fluidounces of water to boil- ing, add the seed, macerate for several hours, stirring frequently, then strain, dissolve the borax and acid in the re- mainder of the water by the aid of heat, add this solution and the glycerin, alco- hol and perfume to the mucilage and mix well by agitation. The water may be used cold but a longer maceration will be required. VII. Quince seed av.oz. % Borax dr. 2 Carbolic acid m. 30 Tincture of benzoin fl.oz. 1 Glycerin fl.oz. 3 Water, to make.. fl.oz. 32 Perfume, to suit. Pour 16 fluidounces of boiling water on the seed, add the borax and acid, let macerate for several hours, agitating oc- casionally. Strain the liquid, mix the residue with 12 fluidounces of boiling water, macerate as before, and again strain. Mix the two colatures, add the. glycerin, incorporate the tincture by agi- tation, perfume with some extract or aromatic oils if desired, and finally add water enough to make 32 fluidounces. The addition of tincture of benzoin makes a milky white product. Toilet Creams Containing Linseed. Linseed may be used like quince seed for making a face cream and produces 946 THE STANDARD FORMULARY an equally acceptable product. The lin- seed should be washed on a sieve with running water to remove adherent dust and dirt. The product may be perfumed and colored as desired. IX. Linseed, whole av.oz. 3 Boric acid av.oz. Vz Oil of rose drops 8 Glvcerin fl.oz. 4 Alcohol fl.oz. 8 Water, to make fl.oz. 32 Wash the linseed on a sieve to remove adherent dust and dirt, macerate in 20 fluidounces of water for 2 or 3 days, agitating frequently, strain the mucilage through cheese-cloth; in the glycerin dissolve the acid by the aid of a gentle heat, then add this solution, and the oil and alcohol to the mucilage, and finally pass enough water through the strainer to make the total liquid measure 32 fluid- ounces. Other perfume may be used instead of oil of rose. X. Linseed, whole av.oz. 4 Boric acid gr. 30 Carbolic acid dr. 2 Cologne water - dr. 3 Glycerin , fl.oz. 3 Alcohol fl.oz. 4 Water, to make fl.oz. 32 Prepare like the preceding. Toilet Creams Containing Irish Moss. In making a toilet cream with Irish moss as a basis, the latter must be boiled with water to extract the mucilaginous substance. Subsequent treatment is the same as in making the other creams, ad- dition of alcohol, glycerin, perfume, etc. XI. Irish moss av.oz. 1 Glvcerin fl.oz. 8 Alcohol fl.oz. 8 B< >ric acid av.oz. 1 Water, to make fl.oz. 64 Perfume, to suit. Heat the moss with a half gallon of boiling water for 5 or 10 minutes, then strain ; in the liquid dissolve the boric acid, add the glycerin, alcohol, and any desired perfume, and finally pass enough warm water through the strainer to make 64 fluidounces. XII. Mucilage of Irish moss, N. F fl.oz. 8 Borax dr. 1 Glycerin fl.oz. 12 Cologne water fl.oz. 4 Water fl.oz. 8 Dissolve the borax in the water and add the other ingredients. Other per- fume may be added instead of the co- logne water. Almond Toilet Cream (Almond Cream). On account of the variety of creams containing almond in some form, a dis- tinction must be made between the fatty and non-fatty creams and those that are actually made with almonds or sweet almond oil and those that merely con- tain oil of bitter almond or benzaldehyde as the odorous agent. The almond cold creams have already been mentioned (see under Cold Cream), the creams containing almond will be mentioned later, and under the present heading are given formulas for two non-fatty creams of the bitter almond odor. Any of the preceding non-greasy skin creams may be made into almond creams by replac- ing the perfume with oil of bitter al- mond or benzaldehyde. XIII. Tragacanth, powder dr. 2 Borax, powder dr. 2 Ammonium chlorid av.oz. y 2 Glycerin fl.oz. 5 Water fl.oz. 27 Oil of bitter almond drops 15 Triturate the tragacanth with the glyc- erin to a smooth paste; dissolve the borax and ammonium chlorid in a por- tion of the water; add this solution, the oil, and the remainder of the water to the mucilage, and mix the whole thor- oughly. The borax and ammonium chlorid may be omitted. FACE AND SKIN PREPARATIONS. 947 XIV. Castile soap, powder dr. 2 Boric acid, powder dr. 1 Tragacanth, powder gr. 90 Glycerin fl.oz. 6 Water fl.oz. 26 Oil of bitter almond drops 20 Triturate the first three ingredients and the oil with the glycerin to a smooth paste, and then incorporate the water. The soap may be omitted if desired, but then the amount of gum will have to be increased to at least 2 drams. Calendula Toilet Cream (Calendula Cream). XV. Tragacanth, powder dr. 2 Borax dr. 2 Ammonium chlorid dr. 4 Tincture of calendula fl.oz. 2 Glycerin fl.oz. 4 Water fl.oz. 26 Triturate the gum with the glycerin to a smooth paste; dissolve the borax and ammonium chlorid in a portion of the water, filter this solution, mix the two liquids, add the remainder of the water, and incorporate the tincture (and some "extract" to perfume) with this mixture by agitation. Any other of the toilet creams may be made into a calendula cream by adding tincture of calendula to it. Camphor Toilet Cream (Camphor Cream). XVI. Quince seed av.oz. x / 2 Water, hot fl.oz. 28 Borax, powder dr. 2 Glycerin fl.oz. 4 Spirit of camphor fl.oz. 2 Oil of bitter almond drops 20 Macerate the quince seed for several hours with the water, stir frequently, strain, add the glycerin and in the mix- ture dissolve the borax. Dissolve the oil in the spirit of camphor and gradu- ally add it to the mucilage and mix thoroughly. Cucumber Toilet Cream. Prepare like any of the preceding creams, replacing a portion of the water with cucumber juice and color a pale green with chlorophyll or green aniline. 6J See formula for Cucumber Juice or Essence. Mentholated Toilet Cream. Any of the previously mentioned toi- let creams may be converted into a men- thol cream by replacing the perfume with a solution of menthol in alcohol. Too large a quantity of menthol must not be used as it may prove irritant and an excess will be precipitated from the aqueous cream. The following formula may be used to make a menthol cream : XVII. Tragacanth, powder dr. 2 Glycerin fl.oz. 1 Menthol gr. 40 Alcohol fl.oz. 2 Water, to make fl.oz. 32 Solution of carmine sufficient Triturate the tragacanth with the glyc- erin, dissolve the menthol in the alcohol, mix the gummy and alcoholic liquids by trituration, color a light pink by the ad- dition of the carmine solution, and then gradually and thoroughly incorporate the water. The coloring matter may be omitted. Violet Toilet Cream. XVIII. Tragacanth, whole dr. 4 Benzoic acid dr. 1 Borax, powder dr. I Water fl.oz. 8 Orange flower water fl.oz. 8 Glycerin fl.oz. 16 Oil of orris m. 30 Jasmine extract fl.dr. 4 Macerate the gum in the water for 1 or 2 days until thoroughly softened ; dis- solve the borax and acid in the mixed glycerin and orange flower water, add this solution and the oil and extract to the mucilage, let stand several days longer, shaking frequently, then strain with pressure through cheese-cloth. More water may be added if necessary. Witch Hazel Toilet Cream. Any of the previously mentioned toilet creams may be made into a witch hazel cream by omitting the perfume and sub- stituting distilled extract of witch hazel for the alcohol and water. Or the fol- lowing may be used: 948 THE STANDARD FORMULARY XIX. Quince seed av.oz. y 2 Borax gr. 20 Glycerin fl.oz. 2 Alcohol fl.oz. 2 Water fl.oz. 1 Distilled ext. of witch hazel. fl.oz. 28 Macerate the seed, glycerin and ex- tract together for about 12 hours, agi- tating frequently, then strain, and add a solution of the borax in the water, and the alcohol. Creams Containing Almond (Aman- dine). Some toilet creams differ from the preceding kind in containing almond in some form, either as an emulsion of sweet or bitter almond, or sweet almond oil in emulsion or saponaceous form, or the almonds and oil may be combined. The creams containing merely oil of bit- ter almonds for the odor are mentioned under a preceding heading entitled Al- mond Toilet Cream, which see. These creams receive such names as "almond cream," "milk of almonds," and "amandine." If a "honey and almond cream" is desired, a portion of the water or glycerin may be replaced with honey. If the preparation is tinted a rose color or is flavored strongly with rose, it may be called "cream of roses." Any of the preparations mentioned below may be so tinted or perfumed. Or any other per- fume may be added. These preparations are used for cleansing, softening and whitening the skin, almonds having the reputation of being particularly effective for this pur- pose. In summer time they may be rec- ommended for removing tan or sun- burn, and in winter time for healing "chaps" and roughness of the skin. See also Gowland's Cosmetic Lotion for a similar preparation containing mercuric chlorid. XX. Sweet almonds av.oz. 2 Sweet almond oil fl.dr. 4 Quince seed av.oz. 1 Borax, powder gr. 30 Alcohol fl.oz. 4 Water, to make fl.oz. 32 Oil of rose or ylang ylang. drops 10 Blanch the almonds and make them into an emulsion with the water, gradu- ally added. Add the quince seed to this liquid, let stand for 12 to 24 hours, stir- ring frequently, and then strain. Dis- solve the borax in 1 ounce of water, add the oil, shake, and mix with the previ- ously prepared liquid, agitating thor- oughly. Now add the alcohol containing the oil, also pass enough water through the strainer to make 32 fluidounces, and mix the whole intimately to secure a uniform product. The oil of rose or ylang ylang used may be synthetic oil, or some other kind of perfume may be employed. XXI. Sweet almonds av.oz. 5 Castile soap, white dr. 2 White wax dr. 2 Spermaceti dr. 2 Oil of bitter almond drops 10 Oil of bergamot drops 20 Alcohol fl.oz. 6 Water sufficient Blanch the almonds and make an emulsion of them with water so as to obtain 16 fluidounces of product, strain- ing through cloth. Dissolve the soap with the aid of heat in 8 fluidounces of water, add the wax and spermaceti, con- tinue the heat until the latter is melted, transfer to a mortar, and incorporate the almond emulsion slowly with con- stant stirring until all has been added and a smooth cream has been formed. Finally add the two volatile oils dis- solved in the alcohol. Honey and Almond Cream. XXII. Honey av.oz. 2 White castile soap, powder. av.oz. 1 Sweet almond oil fl.oz. 26 Oil of bitter almond fl.dr. 1 Oil of bergamot fl.dr. 1 Oil of clove drops 15 Peru balsam dr. 1 Solution of potassa sufficient Mix the honey and soap in a mortar and add enough solution of potassa to FACE AND SKIN PREPARATIONS. 949 make a nice cream, or about I fluidram. Then add the sweet almond oil and other ingredients. TOILET MILKS. Some toilet washes are known by the appellation of "milks." These consist of an oily substance combined with borax, powdered soap, and a large quantity of water, and are therefore in a sense an imperfect and thin soap, the whole being suitably flavored. The oily substance may consist of lanolin, cocoa butter, co- coanut oil or a combination of these. According to this fatty constituent, the preparation receives the name of "cocoa milk," "cacao milk" or "lanolin milk." Another "milk" which is also used is "cucumber milk" or "milk of cucum- bers," which also contains borax, some oil or soap, and cucumber juice. These preparations are used as a sub- stitute for "cold cream" to be applied to the skin at night and may be applied to the face instead of toilet cream before using powder, to enable the- latter to adhere more readily. Cocoa or Cacao Milk. I. Borax dr. 2^ White castile soap dr. i l / z Cocoa butter av.oz. 1 y 2 Cocoanut oil dr. 2 Rose water fl.oz. 30 Triturate the borax and soap, both in powder form, with the cocoa butter and oil and 2.y 2 fluidounces of rose water, in a warmed mortar, until thoroughly mix- ed, then dilute gradually with the re- mainder of the rose water. Any desired perfume may be added. The cocoanut oil may be replaced with sweet almond oil. II. Borax, powder dr. 2^ White castile soap, powder. av.oz. y 2 Cocoanut oil av.oz. y 2 Cocoa butter, grated av.oz. \y 2 Water fl.oz. 2 Rose water fl.oz. 28 Oil of bergamot drops 20 Oil of neroli drops 5 Oil of orris, liquid drop 1 Triturate the first five ingredients to- gether in a warm mortar until well mix- ed, then gradually incorporate the rose water previously warmed to 40 C, and add the essential oils. Cucumber Milk (Milk of Cucum- bers). For the process for making cucumber juice mentioned in the formulas below, see under heading entitled Cucumber Juice or Essence. III. Cucumber juice fl.oz. 8 Sweet almond oil fl.oz. 2 Spirit of soap, N. F fl.oz. 2 Tincture of benzoin fl.dr. 1 Oil of lavender flowers drops 15 Oil of bergamot drops 10 Oil of bitter almond drop 1 Mix the sweet almond and essential oils, shake with the spirit and tincture, and then incorporate the juice, gradually added, with constant agitation. Lanolin Milk. IV. Borax dr. 2^ Soap, white castile dr. 5 Cocoanut oil av.oz. 1 Wool fat, hydrous av.oz. 2^2 Water fl.oz. 2^ Rose water fl.oz. 26 Oil of bergamot drops 10 Oil of neroli drops 10 Oil of rose drops 5 Oil of wintergreen drop 1 Oil of orris, liquid drop 1 Triturate the borax and soap, both in powder form, with the cocoanut oil, fat and water until well mixed, then incor- porate the rose water, previously warm- ed to about 40 C, gradually added, con- tinuing the trituration, and finally add the volatile oils. V. White castile soap, powder... gr. 22 Lanolin av.oz. 1 Tincture of benzoin fl.dr. i l / 2 Distilled water, to make fl.oz. 16 Dissolve the soap in 2 fluidounces of warm water, also rub the lanolin with 2 fluidounces of water until well mixed, then incorporate the two with each oth- er, adding the remainder of the water, finally incorporating the tincture. The latter may be replaced by 90 gr. of pow- dered borax. 950 THE STANDARD FORMULARY MILK OF ROSES. Some toilet preparations are known by this title. As examples may be men- tioned such of the "Creams Containing Almond" (which see), which are per- fumed with rose. The following for- mulas are also used to make prepara- tions passing under this name : I. English formulas. A. Sweet almonds, blanched, .av.oz. i l / 2 Sweet almond oil fl.dr. I Soft soap (as white as pos- sible) dr. i Rose water fl.oz. 12 Oil of rose drops 5 Alcohol fl.oz. 3 Blanch the almonds in the usual man- ner, make them into an emulsion with the rose water, and strain. Triturate the almond oil and soap together and gradually add the emulsion with con- stant stirring. Finally add the oil of rose dissolved in the alcohol. B. Sweet almond oil fl.oz. I Soft soap (as white as pos- sible) av.oz. 1 Potassium carbonate gr. 30 Water, boiling fl.oz. 4 Alcohol fl.oz. 2 Oil of rose drop 1 Rose water, to make fl.oz. 16 Mix the first four ingredients inti- mately, allow to cool, add the alcohol containing the oil of rose, and finally add the rose water. II. French formulas. A. Tincture of benzoin fl.dr. 4 Tincture of storax fl.dr. 2 Spirit of rose fl.dr. 2 Alcohol fl.oz. 2 l / 2 Rose water fl.oz. i6 l / 2 Mix the first four ingredients, and add the rose water gradually with frequent and vigorous agitation. B. Tincture of benzoin fl.dr. 2 Tincture of Peru balsam, .drops 40 Alcolml fl.oz. 2 Rose water fl.oz. 14 Mix the tinctures and alcohol and then add rose water gradually and with vigorous agitation. III. German formula : Diluted solution of lead subacetate fl.dr. 4 Spirit of lavender fl.oz. 1 Alcohol fl.oz. 2 Rose water fl.oz. 12 While this formula is given here for the sake of completeness, its use is not recommended owing to the presence of the ooisonous lead compound. It will be observed that this is en- tirely different from the others. IV. Borax gr. 20 Tincture of benzoin fl.dr. 1 Glycerin fl.oz. 1 Alcohol fl.oz. 1 Rose water fl.oz. 4 TOILET LOTIONS. Under this title are included a miscel- laneous assortment of preparations which are employed instead of some of the preceding "creams" and "milks" for roughness of the skin, cracked hands, chapped lips, etc. They may be denom- inated "face lotion," "glycerin lotion," "cosmetic lotion," "chap lotion," "ben- zoin lotion," or any other name that may seem appropriate. The following lotion is an excellent one: I. Honey dr. 2 Borax dr. 2 Castile soap, white dr. 4 Glycerin fl.oz. 2 Alcohol fl.oz. 2 Water, to make fl.oz. 16 Cochineal coloring or solution of carmine, N. F., sufficient to color. Dissolve the soap and borax in the water by the aid of heat, allow to cool, add the other ingredients, let stand for 24 hours, and filter. Benzoin Lotion (Lait Virginal). Tincture of benzoin fl.dr. 4 Rose water, to make fl.oz. 16 Benzoin and Glycerin Lotion. A mixture of glycerin, tincture of benzoin and rose water is a common household lotion for the hands or face, II. FACE AND SKIN PREPARATIONS. 951 and the usual method of mixing these is unsatisfactory- The following im- proved methods have been suggested: III. Tincture of benzoin fl.dr. 6 Glycerin fl.oz. 4 Rose water, to make fl.oz. 16 Mix the glycerin and rose water in a bottle, shaking well. Then very care- fully pour the tincture on top of the mixture, cork the bottle, and slowly invert the latter once or twice without shaking it. IV. Tincture of benzoin fl.dr. 3 Glycerin fl.oz. 8 Rose water, to make fl.oz. 16 Add the tincture, in repeated portions to 4 fluidounces of glycerin, agitating thoroughly after each addition. Allow the mixture to stand for an hour, and then add, in small amounts and with thorough agitation, enough rose water to make 8 fluidounces. Strain the mix- ture at once through a very finely mesh- ed cloth, rubbing it through with a glass rod or bone spatula. This operation should be repeated 3 or 4 times. Allow the mixture to stand for several hours, add the remainder of the glycerin and shake well, and then add the rose water and again agitate thoroughly. This preparation is best not prepared extemporaneously but . should be made as above and kent as a stock product. Glycerin Lotion. V. Glycerin fl.oz. 3 Rose or orange flower water fl.oz. 13 This may be tinted with solution of carmine or cochineal coloring if de- sired. VI. Glycerin fl.oz. 8 Water fl.oz. 8 Borax dr. 1 White heliotrope or other extract sufficient VII. Glycerin rl.oz. 3 Alcohol . . . fl.oz. 1 Orange flower water fl.oz. 2 Water fl.oz. 10 Borax dr. 2 Oil of neroli drops 8 Oil of bergamot drops 12 Oil of lemon drops 15 Jasmine extract fl.dr. 2 Dissolve the borax in the water, and the oils in the alcohol. Mix the two liquids, add the other ingredients, and filter clear through talcum. This may be colored with cochineal coloring or solution of carmine. Menthol Lotion. VIII. Menthol # gr. 20 Tincture of quillaia fl.dr. 4 Glycerin fl.oz. 2 Water, to make fl.oz. 16 Perfume, to suit. Dissolve the menthol and perfume in the tincture, mix the glycerin and wa- ter, add this gradually to the solution, frequently agitating, then filter. Peroxid Lotion. IX. Glycerin fl.oz. 6 Rose water fl.oz. 6 Hydrogen peroxid fl.oz. 3 This acts as a bleaching agent to the skin. X. Strawberry Lotion. Mashed strawberries fl.oz. 16 White wine vinegar fl.oz. 16 "Rose water fl.oz. 8 Mix the strawberries and vinegar, macerate for 24 hours, strain through muslin, and to the colature add the rose water. This is recommended by a "beauty ex- pert" as an astringent wash for relaxed muscles. Witch Hazel Lotion. XI. Glycerin fl.oz. 4 Rose water fl.oz. 4 Distilled ext. of witch hazel, .fl.oz. 8 "White Glycerin." In different parts of the country vari- ous preparations are put up and sold as "white glycerin." The following are some of the formulas : 952 THE STANDARD FORMULARY I. Bismuth subnitrate dr. 2 Glycerin fl.oz. 4 Mix thoroughly by trituration in a mortar. II. Cologne water fl.oz. 1 Rose water fl.oz. 1 Glycerin fl.oz. 6 III. Tincture of benzoin fl.oz. 2 Glycerin fl.oz. 4 IV. Quince seed dr. 1 Borax, powder dr. I Cologne water fl.oz. 2 Hot water fl.oz. 4 Glycerin fl.oz. 10 Macerate the quince seed in the water for 2 hours, strain, to the mucilage add the other ingredients, and dissolve the borax by agitation. TOILET OR COSMETIC JELLIES. These are preparations of stiff or thick consistence intended as emollient tcilet applications. The body consists of gelatin, starch, tragacanth or similar substance, but most often gelatin is em- ployed. This should be colorless and odorless and otherwise of good quality, there being many inferior grades of gel- atin. On account of the varying absorp- tive power of different kinds of gelatin for water, the qualities given in these formulas may require slight change to produce a jelly of the requisite firmness, but it is believed that the quantities men- tioned will usually prove satisfactory. Starch and tragacanth in the form of the official glycerites are also good bodies for these jellies. Other common ingredients are glyce- rin, water and perfume ("extract," es- sence, volatile oil or synthetic). The per- fume should preferably be one that does not cause opalescence, a transparent product being much handsomer in ap- pearance. Other additions are boric, carbolic or salicylic acid, fluid extract or tincture of arnica or calendula, and distilled extract of witch hazel. These jellies may also be tinted a rose color with cochineal col- oring or solution of carmine, X. F. Owing to their thickness, these prepa- rations must be dispensed in wide- mouthed bottles, screw-cap jars, or col- lapsible tubes. They are used as applications to the face, hands, lips, etc., to heal chaps, re- move roughnesses, soothe the skin, etc., like the toilet creams, milks and lotions. The common appellation for these jel- lies is "glycerin jelly." If containing arnica, they may be known as "arnica jelly"; if containing calendula, "calen- dula jelly"; witch hazel, "witch hazel jelly"; if carbolic acid, "carbolated glyc- erin jelly"; if tinted a rose color and flavored with oil of rose, "rose jelly" or "jelly of roses," etc. Glycerin Jelly. Gelatin av.oz. ^ to 1 Boric acid av.oz. 1 Glycerin fl.oz. 12 Water fl.oz. 20 Perfume, to suit. Dissolve the gelatin in the water by the aid of heat, also the acid in the glyc- erin, mix the two solutions, allow to cool somewhat and incorporate the perfume. The amount of gelatin may be varied to suit the thickness desired. II. Gelatin av.oz. 1^/2 Glycerin fl.oz. 24 Water fl.oz. 5 Oil of rose drops 3 Oil of lavender flowers drops 15 Soak the gelatin in the mixed glycerin and water for 12 hours, then heat on a water bath until dissolved, and finally add the oils. Other perfume may be used. Also other additions may be made; carbolic acid, for example, would make it a car- bolated glycerin jelly. III. Glycerite of starch or of traga- canth may also be used for making a toilet jelly. Any desired perfume may be added; other additions may be made such as carbolic or boric acid. It may FACE AND SKIN PREPARATIONS. 953 also be colored pink with cochineal col- oring or solution of carmine. IV. Gelatin or isinglass av.oz. i Glycerin av.oz. 20 Water av.oz. 20 Boric acid dr. 2 Soak the gelatin in the water until soft, then heat until dissolved; and, when it cools down a little, add the white of an egg to it. Mix well, and again heat, to coagulate the albumin; add the other ingredients, and strain while hot. Perfume with any desired odor. If the gelatin gives a clear solu- tion, the white of egg need not be added. Glycerin and Honey Jelly. A small amount of honey may be add- ed to any of the preceding glycerin jel- lies or the following may be used : V. Glycerin fl.oz. 4 Clarified honey fl.dr. 4 Distilled water fl.oz. 8 Gelatin av.oz. J / 2 Oil of lavender flowers drops 12 Soak the gelatin in the water and honey until it softens and swells up; then melt by the aid of heat, and add the glycerin, previously warmed, strain through fine muslin, and when nearly cool add the perfume and pour into wide-mouthed bottles or screw-cap jars. Arnica Jelly. Any of the preceding glycerin jellies may be converted into an arnica jelly by replacing a portion of the water or glyc- erin with tincture or fluid extract of arnica, or the following may be used : VI. Fluid extract of arnica fl.oz. 1 Glycerin fl.oz. 6 to 8 Gelatin av.oz. I Water fl.oz. 16 Cover the gelatin, contained in a suit- able vessel, with the water; allow it to macerate until soft and pliable; then heat with the water and add the glyce- rin, the quantity of the latter varying with the season, using more in the win- ter than in hot weather. When dissolv- ed, add the fluid extract, and transfer to containers. Calendula Jelly. This may be made like any of the pre- ceding arnica jellies, but substituting fluid extract of calendula for the fluid extract or tincture of arnica, or use the following : VII. Glycerite of starch av.oz. 14 Fluid extract of calendula, .fl.oz. 1^ Cochineal coloring or solution of carmine, sufficient to color a rose tint. Oil of rose, sufficient to perfume. Lanolin Jelly or Glycerite. VIII. Glycerite of starch av.oz. 12 Wool-fat, hydrous av.oz. 4 Triturate the fat with a small portion of glycerite until thoroughly mixed, then add the remainder of the glycerite grad- ually, rubbing thoroughly after each ad- dition. Any suitable perfume may be added. The glycerite had best be slight- ly warmed before adding the wool-fat. Witch Hazel Jelly. Any of the glycerin jellies may be used by substituting distilled extract of witch hazel for a portion of the water, or use the following : IX. Gelatin av.oz. 1 Glycerin fl.oz. 3 Distilled ext. of witch hazel. fl.oz. 20 Dissolve the gelatin in the mixed glyc- erin and extract with the aid of a water- bath, then strain, and perfume if de- sired. SOLIDIFIED GLYCERIN (Glycerin Honey). Several combinations have received this name, one being glycerite of starch, which is suitably perfumed and dis- pensed in screw-cap jars, wide-mouthed bottles or collapsible tubes. Another is prepared as follows: Transparent soap av.oz. 1 Water fl.oz. 4 Glycerin fl.oz. 24 Perfume, to suit. Cut the soap into fine shavings, heat on a water bath with 4 fluidounces each of glycerin and water until dissolved, oc- 954 THE STANDARD FORMULARY casionally adding water to restore the original volume, then add the remainder of the glycerin and the perfume, and transfer to suitable containers. This is to be used as an application to the skin like the glycerin jellies. CAMPHOR ICES. (Compound Cam- phor Cerate.) These are solid preparations contain- ing fatty bodies like wax and spermaceti in combination with camphor, and are intended for inunction of the hands and face where there is roughness or crack- ing of the skin. They are prapared by melting the fatty substances, allowing to cool somewhat, stirring in the camphor, allowing to cool, adding aromatic oils, if the latter are used, and pouring into molds. The best material for the latter is block tin. These may be chilled be- fore casting the mixture, as this renders adhesion less likely. Much cheaper, though less elegant, molds may be made of tinned iron. The mixture may be poured into a large mold and the mass may subsequently be cut into smaller ob- long cakes, or the mixture may be at once poured into individual molds. The usual way of putting up camphor ice for sale is to wrap it first in thin oiled paper, then in an outer covering of tin-foil, and lastly to enclose it in a paper or ornamental tin box. Camphor ice may be known by this title; if it contain glycerin as "glycerin camphor ice"; if containing cocoa butter as "cocoa camphor ice," and if contain- ing petrolatum as "petrolatum camphor ice." The quantity of camphor in these for- mulas may be altered within very wide limits. Larger or smaller amounts may be used at the option of the operator. I. Formula of the National Formulary : White wax av.oz. 2J/2 Spermaceti av.oz. 8 Castor oil av.oz. 4%. Camphor av.oz. 1^ Benzoic acid gr. 75 Carbolic acid gr. 15 Oil of bitter almond drops 12 av.oz. 5 av.oz. 2 av.oz. 7^2 av.oz. \ x /2 7 4 6 1 Melt the wax and spermaceti on a water bath, add the oil and camphor, the latter first broken into small pieces, and continue the heating and stirring until the camphor is dissolved. Then with- draw the heat, cover the vessel, and when the mixture has cooled somewhat, add the remaining ingredients, and thor- oughly incorporate by stirring. Lastly, pour into molds, allow to solidify, cut into small blocks, and wrap and box in the usual manner. II. White wax Spermaceti Benzoinated lard Camphor Prepare like the preceding. III. Spermaceti .av.oz Lard av.oz Wool-fat, hydrous av.oz Sweet almond oil fl.oz Camphor av.oz Benzoic acid gr. 20 Oil of cajuput drops 30 Prepare like No. I. IV. Paraffin wax Spermaceti White wax Sweet almond oil . . Camphor, powdered Prepare like No. I. V. White wax Spermaceti Stearin Lard Camphor Prepare like No. I. Cocoa Camphor Ice VI. Cocoa butter White wax Benzoinated lard Spermaceti Camphor .... Prepare like any of the preceding camphor ices. Glycerin Camphor Ice. (Compound Glycerin Cream.) VII. White wax av.oz. 2J/3 Spermaceti av.oz. 2}4 . av.oz. 8 .av.oz. 4 . av.oz. 4' . .fl.oz. 16 .av.oz. 1 . av.oz. 5 .av.oz. 5 .av.oz. 8 .av.oz. 10 .av.oz. 2 ..av.oz. y 2 . .av.oz. 3 . .av.oz. 4 . .av.oz. 8 . .av.oz. i l / 2 FACE AND SKIN PREPARATIONS. 955 Stearin (stearic acid) av.oz. 4 Lard av.oz. 5 Borax, powder gr. 30 t Glycerin fl.dr. 4 Camphor av.oz. 1 Melt the first four ingredients on a water bath. Dissolve the borax in the glycerin. Add the latter gradually to the former; when at the point of cooling, stir well, add the camphor in pieces, stir again until dissolved and pour into molds. It is not possible to add much glycerin to camphor ice. The above contains about as much as it will take up. Petrolatum Camphor Ice. VIII. Paraffin wax av.oz. 5 White petrolatum av.oz. 8 White wax av.oz. 3 Camphor av.oz. 1 Melt the two waxes together at a gen- tle heat, add the petrolatum and cam- phor, the latter in small pieces or pow- dered, stir until the camphor is dissolv- ed, pour the mixture into molds, allow to cool, cut into small cakes, and wrap and box in the usual manner. IX. White wax av.oz. i l / 2 Spermaceti av.oz. &/ 2 White petrolatum av.oz. 1 Camphor av.oz. 1 Prepare like the preceding. CAMPHOR BALL. This is the same thing as camphor ice. The following formula may be used: Spermaceti av.oz. 3 White wax av.oz. 9 Cottonseed oil * av.oz. 3^2 Camphor av.oz. 3 Prepare like camphor ice'^md put up for sale in the same manner. TOILET OR COSMETIC POMADES. Hard preparations, which may be call- ed toilet pomades, intended to take the place of the softer "cold cream" and of camphor ice, may find a ready sale. These preparations are not so greasy as "cold cream" and may be carried about, readily in the pocket or hand-bag. For- mulas for a number of such preparations are here given as we.ll as for some other similar articles. These may be put up like camphor ice or be dispensed in fancy jars. Cocoa Emollient. I. Cocoa butter av.oz. 6 White wax av.oz. 6 Sweet almond oil fl.oz. 6 Oil of lavender flowers fl.dr. 2 Oil of rosemary fl.dr. 2 Melt the wax and cocoa butter at a gentle heat, then incorporate the oils. Other aromatic oils may be added, also synthetic perfumes, or these may be omitted entirely, the cocoa butter having a pleasant aroma of its own. This product may be dispensed in cakes like camphor ice. It is a pleasant application for the skin to take the place of the softer "cold creams" and of camphor ice which is objectionable to some persons. II. Cocoa butter av.oz. 12 Sweet almond, castor or cot- tonseed oil fl.oz. 4 Melt the cocoa butter, add the oil, al- low to congeal, and form into cakes. It may be perfumed with oil of rose or other perfume. It may be used like No. 1. Almond Tablets. III. Spermaceti av.oz. 4 White wax av.oz. 8 Sweet almond or other simi- lar oil fl.oz. 4 Oil of bitter almond drops 40 Oil of pimento drops 10 Prepare like camphor ice and put up in the same manner. Menthol Tablet. Prepare like. almond tablet but substi- tuting 2 or 3 drams of menthol for the oils. Scented Paraffin Cakes. IV. Paraffin wax av.oz. 5 White petrolatum av.oz. 10 Heliotropin gr. 50 Oil of bergamot drops 25 Oil of lavender flowers drops 2$ Oil of clove drops 10 Prepare like the preceding tablets. 956 THE STANDARD FORMULARY Lanolin Pomade. Under this heading is included a fatty combination consisting mainly of wool- fat, which may be put up in stick form by the method of casting in molds as described under Camphor Ice, which see. V. Mutton suet av.oz. 3 Wool-fat, hydrous av.oz. 6 Boric acid, powder av.oz. 1 Melt the suet, add the wool-fat, stir in the acid, and form into sticks. LANOLIN PASTE OR CREAM. I. Wool-fat, hydrous av.oz. 2 Tincture of quillaja fl.oz. 1 Gelatin av.oz. ^ Glycerin fl.oz. 4 Water fl.oz. 15 Perfume, to suit. Dissolve the gelatin in the water by the aid of heat, triturate the wool-fat with the tincture of a warm mortar un- til emulsified, then incorporate the warm gelatin solution, and finally add any de- sired perfume. This paste is to be used for the same purposes as "cold cream" or toilet jelly. II. Wool-fat, hydrous av.oz. 2 White petrolatum av.oz. 6 Glycerin fl.oz. 4 to 8 Perfume, to suit. This is also an excellent toilet prepa- ration. It may be made softer or harder by the addition of the larger or smaller quantity of glycerin. Mentholated Lanolin Cream. III. Menthol gr. 40 Salol gr. 80 Olive oil fl.dr. 2 Wool-fat, hydrous av.oz. 8 Triturate the menthol and salol to- gether until liquefied, then incorporate the oil and fat. ALMOND MEAL. (Mandelklei.) This is a preparation used in place of soap, for cleaning the face and hands, more particularly the latter. It is gen- erally made from bitter or sweet al- monds, usually the latter, or from al- monds from which the oil has been ex- . av.oz. av.oz. .fl.dr. drops 8 pressed. Whichever is used it must be reduced to either a fine or a moderately fine powder, and then mixed with vari- ous other detergent agents such as pow- dered orris root, soap, wheat flour, borax, etc., and also with aromatic agents such as oils of bitter almonds, lemon, bergamot, etc., or synthetics. The almonds may be blanched or not, the product in the former case being much lighter in color. In some formulas the almonds are entirely omitted, as the detergent prop- erties are mainly due to other ingredi- ents any way. I. Sweet almonds, blanched and powdered av.oz. 8 Wheat flour Orris root, powder., Oil of lemon Oil of bitter almond II. Sweet almonds av.oz. 8 Rice flour av.oz. 8 Orris root, powder av.oz. 4 White castile soap, powder. av.oz. 1 Borax, powder av.oz. 1 Oil of bitter almonds drops 20 Blanch the almonds, then dry them, powder them in a mortar, and mix in- timately with the other ingredients. III. Corn starch av.oz. 5 Orris root, powder av.oz. 15 Talcum av.oz. 25 Borax, powder av.oz. 4 Oil of bergamot drops 30 Oil of lemon drops 10 Oil of neroli drops 5 Tincture of musk drops 15 This fjmiula does not call for al- mond, hence the name almond meal is a misnomer. However, it is an ex- cellent detersive agent. Any of the preceding formulas may also be used if the almond is omitted and will fur- nish desirable products. Sanded Almond Meal. (Sand Man- delklei.) This is offered for use in various unclean conditions of the skin when the preceding is not sufficiently deter- gent. FACE AND SKIN PREPARATIONS. 957 IV. Borax av.oz. I Glycerin fl.oz. 2 Sand av.oz. 8 Sweet almonds, powdered, or ground almond-meal cake av.oz. 20 Oil of bitter almond or benzaldehyde fl.dr. 1 Dissolve the borax in the glycerin by the aid of heat, mix this intimately with the sand, and then add the other ingredients. The sand must be white sand in the finest possible powder. TOILET OATMEAL. This is to be used for the same purposes and in the same manner as almond meal, which see. I. Oatmeal av.oz. 8 Sweet almonds av.oz. 8 Perfume to suit The almonds may be blanched or not, as preferred, or the residue after ex- traction of oil may be used. II. Oatmeal, fine powder av.oz. 16 Orris root, powder av.oz. 2 Oil of neroli drops 10 Oil of bergamot drops 20 Or 10% solution of ionone may be substituted for the oils. The propor- tions of oatmeal and orris may also be altered at will. PISTACHIO MEAL. This may take place of almond meal. Pistachio nuts, powdered, .av.oz. 8 Orris root, powdered av.oz. 8 Oil of neroli drops 20 Oil of lemon drops 20 ALMOND PASTE. (Amandine.) These are used for cleansing pur- poses the same as almond meal. In fact the meals may be converted into pastes by the addition of sweet almond oil or soft soap and plain or rose water or glycerin. I. Mme. Qui Vive's formula: Bitter almonds av.oz. 7 Orris root, powder av.oz. i^> White castile soap powder. av.oz. i l / 2 Glycerite of starch av.oz 3^2 Honey oz. 2 Oil of lavender flowers fl.dr. I Oil of bergamot fl.dr. 1 Oil of bitter almond drops 8 Blanch the almonds, heat them with a small quantity of water to a smooth paste, add the other ingredients, and mix intimately. It may be colored with a solution of cochineal. The bitter al- monds may be replaced by sweet al- monds. II. Sweet almonds av.oz. 24 Rice flour av.oz. 4 Orris root, powder av.oz. 4 White castile soap, powder. av.oz. 2 Spermaceti avA T / 2 Sweet almond oil av.oz. 2 Oil of rose drops 15 Oil of bitter almond fl.dr. 1 Oil of bergamot fl.dr. 2 Rose water sufficient Blanch the almonds in the usual man- ner, then rub to powder in a mortar, add the rice flour and orris root and beat with enough rose water to make a smooth paste. Also melt the sper- maceti, add the sweet almond oil and the soap, and with this gradually and thoroughly incorporate the previously prepared mixture. Finally add the vo- latile oils. III. Honey fl.oz. 4 Soft (green) soap av.oz. 2 Peru balsam dr. 2 Oil of bergamot fl.dr. 1 Oil of bitter almond fl.dr. 1 Sweet almond oil fl.oz. 14 Triturate the sweet almond oil to a smooth paste with the soap, then gradually incorporate the honey and other ingredients. IV. Soft (green) soap, light color av.oz. 1*7 White castile soap, powder. av.oz. 3 Talcum av.oz. 5 Borax, powder av.oz. Y> Sodium carbonate, dried. . .av.oz. Y\ Oil of bitter almond fl.dr. 2 Cologne water fl.oz. 1 Glycerin* fl.oz. 2 Rose water, fl.oz. 3 or sufficient Dissolve the borax and sodium car- bonate in the rose water and glycerin, 958 THE STANDARD FORMULARY and rub this and the oil and cologne with the two soaps to form a smooth mixture, after which the talcum is to be incorporated. More rose water may be added in the meantime to make a mass of the requisite consistency. PASTE OR OINTMENT FOR COS- METIC GLOVES. By cosmetics gloves are meant kid or cotton gloves several sizes too large, which are to be smeared on the inside with any suitable paste, ointment or cream, and then to be worn at night for the purpose of softening the hands or keeping them soft or for healing crack- ed skin. "Cold cream" or any other kind of a cream or emollient may be used on the gloves, and the following are also recommended. I. This preparation has been recommend- ed by a "beauty expert" under the name "honey and almond paste for cosmetic gloves" : Almond meal av.oz. 4 Sweet almond oil fl.oz. 8 Honey fl.oz. 8 Egg yolk fl. or av.oz. Vi Knead the almond meal, honey, and egg-yolk together, then add the oil, and work up into a smooth paste. II. Here is another paste also offered by a "beauty expert" : Sweet almond oil fl.oz. 2 Glycerin fl.oz. 1 Rice flour av.oz. 1 Rose water fl.oz. 6 Tincture of benzoin fl.dr. 3 Yolk of 2 eggs. Rub up the oil, glycerin, rice flour, and egg yolk together, then incorporate the rose water and benzoin. COMPLEXION OR FACE POWDERS. Complexion powders contain such constituents as talcum, starch, precipi- tated chalk, bismuth subnitrate, oxid, hydrate, subcarbonate or oxychlorid, zinc oxid, magnesium carbonate or oxid, and orris root, together with suitable perfume and with coloring matter if a colored powder be desired. These solids must be in the form of fine powder, must be intimately mixed, and then sifted through a fine bolting cloth sieve; whatever fails to pass through the sieve must be returned to the mortar and be still further triturated until all will pass through. If colored powder is to be prepared, the coloring matter should be added to the powder before sifting and should be very thoroughly triturated with a small portion of the powder be- fore adding the remainder of the pow- der. After sifting, the perfume may be added; the whole should be again passed through the sieve to break up any lumps which may have formed by the addition of the moist perfume to the dry pow- der. If a flesh-colored powder is desired, carmine is employed as the coloring agent. A so-called pink powder is more reddish than the flesh-colored, and more carmine may be used, or also Armenian bole. Sometimes a brunette powder is desired and then burnt umber or sienna is used as the coloring agent; cream powder is prepared by the use of cad- mium yellow or chrome yellow (lead chromate), a trace of carmine being added sometimes; a rachel tint is im- parted by means of powdered turmeric or yellow ochre. In the formulas given below, no coloring agents are men- tioned, being intended that these should be added only as desired. In preparing face powders, the best materials should be employed. For ex- ample, Hubbuck's or other first-class zinc oxid should be used. The best talcum is what is known as Venetian chalk; the best precipitated chalk is th; kind known as the English; the pre- ferred bismuth compounds are the light variety which are now readily obtain- able. Owing to their poisonous nature, lead and mercury compounds such as flake white and calomel should never be used. The perfume may be altered at pleas- ure. Various combinations of essential oils, "extracts," and synthetics may be FACE AND SKIN PREPARATIONS. 959 used. Essential oils may always be replaced by the corresponding synthetics as oils of rose and ylang ylang by the artificial oils, oil of bergamot by linalyl acetate, and so on. It may be mentioned here that the so-called "rice powders" contain little or no rice flour or starch and this sub- stance possesses no particular merit as a cosmetic any way. I. Talcum, powder av.oz. 10 Starch av.oz. i Orris root av.oz. I Oil of bergamot drops 8 II. Talcum, powder av.oz. 16 Bismuth oxid av.oz. I Zinc oxid av.oz. I Perfume to suit. III. Rice powder av.oz. 14 Zinc oxid av.oz. 4 Precipitated chalk av.oz. 4 Talcum powder. ......... .av.oz. 2 Orris root, powder av.oz. 2 Perfume to suit. IV. Rice flour av.oz. 16 Zinc oxid av.oz. 2 Orris root, powder av.oz. 2 Oil of rose drops 9 Oil of rose geranium drops 3 Oil of ylang ylang drop 1 Mix the first three ingredients, mix the other ingredients and incorporate this mixture with the powder. V. Corn starch av.oz. 15 Talcum, powder av.oz. 5 Zinc oxid av.oz. 5 Chalk, prepared av.oz. 2^2 Essence of jasmine fl.dr. 4 Oil of bergamot drops 15 Oil of rose drops 8 Oil or neroli drops 8 Oil of ylang ylang drops 2 Oil of orris, liquid drop I Tincture of musk drops 5 VI. Corn starch av.oz. 7 Talcum, powder av.oz. 7 Zinc oxid av.oz. 4 Orris root, powder av.oz. 2 Oil of bergamot drops 20 Oil of rose drops 10 Oil of neroli drops 5 Tincture of musk drops 4 Mix the first four ingredients inti- mately, and add the oils and tincture. Consuelo Face Powder. VII. Mme. Qui Vive's: Talcum av.oz. 10 Rice flour av.oz. 10 Zinc oxid av.oz. 5 Oil of ylang ylang drops 4 Oil of bergamot drops 4 Oil of neroli drops 4 This is also known as "Sarah Bern- hardt's face powder," also as "La Dia- phane." Fatty Face Powder. Fat in the form of wool-fat is intro- duced into some face powders, owing to dryness of the skin or to prevent the latter from becoming dry and sca^y. The^ fat imparts to the powder a de- sirable smoothness, increases the power of adherence to the skin, and helps to preserve the latter in a smooth and sup- ple condition. To prepare such a powder anhydrous wool-fat is dissolved in some volatile solvent like ether or chloroform, this solution is rapidly and intimately mixed with the powdery ingredients, the mix- ture is spread out and exposed to the air until all the solvent has vaporized, and the residue triturated with the re- maining ingredients of the face powder. Anhydrous wool-fat is soluble in two parts of ether and it has been suggested that this solution be mixed intimately with enough magnesium carbonate to make up three times the weight of the w r ool-fat originally employed. After/ exposure to the air to dry, other ingredi- ents are to be added. The mixture may be perfumed and colored in the usual manner. Instead of magnesium carbonate, any other absorbent powder may be employed. If there be no anhy- drous wool-fat on hand, the hydrous kind may be used by shaking it with the requisite amount of ether and allowing 960 THE STANDARD FORMULARY the mixture to stand for several days so that the ethereal and aqueous portions may separate. The ethereal portion may then be used in the regular manner. COMPLEXION TABLETS. Any of the preceding powders may be converted into the tablet or cake form by beating into a stiff paste with water, pressing into suitable molds, and then drying. It may be necessary to add a small amount of powdered tragacanth to hold the powder together while it is being made into the mass form. LIQUID COSMETICS. (Liquid Face Paints.) Any of the face powders may be con- verted into lotions by mixing with water, which may or may not be perfumed or colored; a small amount of glycerin is frequently added. The powders do not dissolve, but are simply suspended by shaking. These liquids are used instead of face powders. Substances suitable for the purpose indicated are : Prepared chalk, magne- sium carbonate, zinc oxid, the oxy- chlorid or subnitrate of bismuth. The last two resemble chalk in density, but much excel it in whiteness. Unscrupulous or careless persons sometimes use white lead (flake white) in the preparation of cosmetics, and cal- omel is said to be the chief ingredient of a proprietary cosmetic that has had some reputation. The character of both these substances renders their use for such purposes dangerous, as even exter- nal application may produce the consti- tutional effects of lead or mercury. In making these preparations a per- fectly smooth mixture must be made by long trituration, preferably rubbing the powder first with the glycerin. If a white preparation is desired, no color- ing agent is added; but if a flesh-colored preparation, then solution of carmine or an alcoholic solution of eosin must be added. No coloring agent or perfume is mentioned in the formulas below as these may be added as desired. av.oz. 1V2 av.oz. 1/2 fl.oz. 2 fl.oz. 24 fl.oz. 4 These liquid cosmetics are usually known by such titles as "face or skin enamel," "oriental cream," "pearl cream," "liquid pearl," "balm," "liquid face paint," etc. They are usually dis- pensed in white (opaque) bottles. I. Zinc oxid Bismuth oxychlorid. Glycerin Water White rose extract. Rub the powders with the glycerin to a very smooth paste, then add the water and perfume. II. Zinc oxid av.oz. Glycerin fl.oz. Water fl.oz. Oil of bergamot drops Oil of lemon drops III. Bismuth oxychlorid av.oz. Precipitated chalk av.oz. Glycerin fl.oz. Water fl.oz. IV. The following "bismuth cream" is an excellent face enamel : Bismuth subnitrate... Nitric acid, U. S. P. Ammonium carbonate Distilled water Glycerin, to make. . . . Mix the acid with 4 x / 2 fluidounces of water, in this dissolve the bismuth sub- nitrate, and pour the mixture very slowly and with constant stirring into a solution of the ammonium carbonate in the remainder of the water. Allow the precipitate to subside, wash it twice with water by decantation, collect on a fine muslin strainer, allow to drain, and mix the residue with enough glycerin to make 16 fluidounces. Dilute this with more water to the required consistency, and perfume and color as desired. V. Zinc sulfate av.oz. 10 3 6 1/2 30 . .av.oz. 10 ...fl.oz. 5 ..av.oz. &/ 2 . . .fl.oz. 50 . . .fl.oz. 16 Sodium carbonate. . Talcum Distilled water Essence of jasmine. Oil of bergamot .. .av.oz. 10 ...av.oz. 6 . . . sufficient . ...fl.dr. 2] . . .drops 10 FACE AND SKIN PREPARATIONS. 961 Oil of rose drops 5 Oil of neroli drops 5 Oil of ylang ylang drop 1 Oil of orris, liquid drop 1 Tincture of musk drops 5 Dissolve the zinc sulfate and sodium carbonate each in 32 fluidounces of dis- tilled water, then slowly pour these solu- tions simultaneously, with constant stir- ring into 10 pints of distilled water. Collect the precipitate on a fine muslin strainer, allow it to drain, transfer it to a mortar, triturate it intimately with 6 l /z av. ounces of finely powdered talcum and add enough distilled water* to make the mixture weigh 32 av. ounces. Lastly add the oils and tincture. VI. The following is a modification of the old familiar flake white mixture: Flake white av.oz. 8 Glycerin fl.oz. 1 Bay rum fl.oz. 1 Rose water fl.oz. 1 Water fl.oz. 24 Various proportions of these ingredi- ents may be used and other perfumes may be added. Owing to the poisonous character of the flake white it is ad- visable to replace it with zinc oxid. BOUGES. These are preparations of deep red tint employed usually for heightening the color of the cheeks. They may be in liquid, ointment, or tablet forms. The coloring agent is either carmine, eosin, or rosanilin. The liquid preparations receive a fanciful name like "vinegar rouge," (if a small amount of acetic acid be added) "maiden's blush," or "bloom of roses." The tablet form is usually called "theater rouge." Nos. VI and VII are different from the others; they contain alloxan, which turns on exposure. I. Carmine dr. I Ammonia water fl.dr. 6 Water fl.oz. 7 Spirit of rose fl.dr. 2 Mix, set aside 24 hours or longer if necessary, agitating frequently till the ammonia has evaporated, then filter. ...gr. 24 .fl.dr. 3 .fl.dr. I .fl.oz. tf/2 .fl.oz. 3 II. Eosin Water , Glycerin Alcohol Cologne water Mix and dissolve. III. Rhodamin gr. 8 Eosin gr. 16 Glycerin fl.di . 2 Oil of rose, artificial. ... .drops 8 Alcohol fl.oz. 1 Rose water, to make fl.oz. 8 Dissolve the rhodamin and eosin in the rose water by the aid of heat, add the glycerin, allow to cool, and add the oil of rose dissolved in the alcohol. IV. Carmine dr. V/2 Acacia, powder dr. 3 Talcum av.oz. 4 Mix all intimately, rubbing to very fine powder, then add water in small proportions to make a doughy mass, and form into round tablets of about the diameter of a silver dollar. V. Paraffin wax av.oz. 4 Petrolatum, white av.oz. 6 Eosin dr. 4 Oil of bitter almond. drops 20 Heat the paraffin at a gentle heat, add the petrolatum, stir well, allow to cool somewhat, and finally add the oil. VI. This preparation has been called Schnonda or Rose Sympathique.lt con- tains alloxan, a white crystalline sub- stance derived from uric acid which turns red on exposure to the air. It is best mixed with fatty substances to form a white cream, as follows: Sweet almond oil fl.oz. 6 Spermaceti av.oz. 1 ^ White wax av.oz. 1 1 / 2 Distilled water fl.oz. 2 Oil of bergamot m. 75 Oil of lemon m. 30 Oil of rose, synthetic m. 15 Melt the spermaceti and wax together, add the alloxan, and rub together until the latter is well mixed. Now add the 962 THE STANDARD FORMULARY warmed almond oil and rose water, and continue trituration until a smooth cream is obtained. In using, rub this cream lightly upon the skin; the atmosphere causes the anointed parts to turn reddish. VII. Lard av.oz. 4 White petrolatum av.oz. 4 Alloxan dr. 1 Oil of orris, liquid drops 20 Melt the lard and petrolatum, rub the alloxan with this mixture, and incor- porate the oil. Use like the preceding. GREASE PAINTS. A good basis for grease paints for theatrical purposes, for eye-brow pen- cils, and for stick cosmetics may be made according to the following for- mula: Cersin av.oz. 3 Petrolatum av.oz. 4 Wool-fat av.oz. 4 White wax av.oz. 6 Olive oil av.oz. 12 Melt the white wax and ceresin to- gether, add the petrolatum and wool- fat, and when all are melted, incor- porate the oil. The coloring substance should be triturated uniformly and to the desired color with a sufficiency of powdered talcum, after which this is in- corporated with the fatty mixture. The whole is then to be cast into suitable molds. The coloring substance used depends on the color desired. The following are used : Zinc oxid, sienna, umber, carmine, rhodamin, eosin, animal char- coal, lampblack, and many of the anilines. BLUE PENCILS FOR VEINS. These are used to accentuate the course of the veins. They may be made with a basis the same as the grease paints, which see. Prussian blue is used as the coloring agent. FACE BLEACHES. (Skin White- ners.) Under this name arc marketed a number of preparations of which the principal or active constituent is corro- sive sublimate. The use of such nrepa- rations is not countenanced, and the following formula is given only because the preparation is in occasional demand : Mercury bichlorid gr. 1 Emulsion of bitter almond, .fl.oz. 12 Tincture of benzoin fl.dr. 1 The mercury salt is dissolved in the emulsion and the mixture gradually added to the tincture. This preparation does not keep long; should be kept in small opaque vials and be dispensed only with a "shake well" label. The emulsion may be prepared from one av. ounce of bitter almond. Other "bleaches" contain from one- half to one grain corrosive sublimate to the fluidounce. The above is known as Hebra's Ori- ental Cosmetic Water. Another similar preparation is Gow- land's Cosmetic Lotion, which see. Another preparation which is said to be used as a face bleach is this : Lactic acid, U. S. P fl.oz. 2 Glycerin fl.oz. 4 Tincture of benzoin fl.dr. 2 Water, to make fl.oz. 32 Mix, perfume as desired, and filter clear through kaolin or talcum. It may also be tinted with carmine. Hydrogen peroxid is the latest, most useful, and least harmful skin bleach. It is usually applied in a somewhat diluted form or in the form of peroxid cold cream, or peroxid lotion. See for- mulas for latter. The following is recommended as a cream containing hydrogen peroxid : Hydrogen peroxid fl.oz. 4 Glycerin fl.oz. 3^ Borax, powder dr. 2 Sweet almond oil fl.oz. 2^2 Wool- fat, hydrous av.oz. 8 Triturate the wool-fat with the oil until well mixed, then thoroughly in- corporate with this a solution of the borax in the glycerin and peroxid. This cream may be perfumed as desired. Another cream of a different order, recommended for the same purpose is the following : FACE AND SKIN PREPARATIONS. 963 Ointment of ammoniated mercury av.oz. I Ointment of zinc oxid. .. .av.oz. I Sweet almond oil fl.oz. 2 Wool-fat, hydrous ...av.oz. 6 Borax, powder dr. 3 Rose water fl.oz. 2 Glycerin .fl.oz. 6 Nitric acid drops 3 Mix the ointments, oil and fat, incor- porate with a solution of the borax in the mixed glycerin and water, and finally add the acid. Gowland's Cosmetic Lotion. Bitter almonds av.oz. \Y\ Mercuric chlorid gr. 90 Ammonium chlorid dr. 3 Alcohol fl.oz. 3 Cherry-laurel water. ...... .fl.oz. 3^2 Water fl.oz. 10 Blanch the almonds, make an emul- sion of them with the water, and strain ; also dissolve the two chlorids in the cherry-laurel water, add the alcohol, and mix this liquid with the emulsion. This is recommended for freckles and tan and as a skin bleach. It should be applied at night and washed off in the morning, after which any toilet cream or emollient or "cold cream" should be applied. Copeland's Cosmetic Water. Emulsion of bitter almonds, .fl.oz. 3^2 Borax dr. 1 Tincture of benzoin .fl.dr. 2 Rose water fl.oz. 4 Orange flower water fl.oz. 4 The emulsion may be prepared from one-half av. ounce of bitter almonds. This is to be used like the preceding. Goddard's Cosmetic Lotion. Mercuric chlorid gr. 6 Tincture of benzoin fl.dr. 2 Rose water fl.oz. 6 HAND CLEANERS OR WHITE- NERS. I. This makes a nice hand-cleaning paste, especially adapted for ladies : White castile soap, powder. av.oz. 8 Orris root, powder av.oz. 2 Corn starch dr. 3 Glycerin fl.oz. 3 Oil of neroli m. 40 Oil of lemon fl.dr. \]/ 2 61 Rub the starch with the glycerin un- til well mixed, then heat in a porcelain capsule to about 285 F. until a trans- lucent jelly is formed; then incorporate the other ingredients. More glycerin or some water may be added if it is too thick. II. This is recommended for dirt which is ground into the pores of the hands. Egg albumen ..av.oz. 5 Boric acid dr. 5 Glycerin fl.oz. 16 Distilled water, to make fl.oz. 32 Perfume, to suit. Dissolve the acid in some of the water, mix this with the remaining ingredients, and strain. In using, wash the hands in the usual manner, dry on a towel, then moisten lightly but thoroughly with the liquid and dry on a soft towel. Also apply at night before retiring, wiping slightly to remove superfluous liquid, or better still, wear cotton gloves during the night. III. White castile soap, powder. av.oz. 5 Pumice, powder av.oz. ]/ 2 Kaolin av.oz. y 1 / Sodium perborate av.oz. 7,V 2 This is an excellent cleanser and bleacher. IV. This ointment is recommended for whitening the hands : Bismuth oxychlorid av.oz. i 1 / Zinc oxid av.oz. 2^2 Olive oil fl.oz. 6 Wool-fat, hydrous... av.oz. 15 Glycerin fl.oz. 2V2 Rose water fl.oz. 5 TOILET AND NURSERY POW- DERS. (Infant Powders — Baby Powders — Dusting Powders.) These are mixtures of talcum, starch, rice flour, boric acid, orris root, zinc oxid, and similar substances to which perfumes may be added. These powders should be reduced to an impalpable con- dition by sifting through a fine sieve Especially is the fine condition required for nursery purposes. 964 THE STANDARD FORMULARY These powders are not adapted to take the place of the so-called "face pow- ders" as they are lacking: in what may be termed "coating" quality (Deckkraft in German). They are applied to the face and neck by ladies after washing to overcome the shininess of the skin, and by men after shaving. In the nur- sery they are useful to apply to infant's bodies after bathing. In the summer time they are used to absorb perspira- tion and to apply before exposure to the hot rays of the sun to avoid sunburn. As an absorbent after night-sweats and during fevers, they are especially grate- ful. They are also applied to portions of the body, such as under the arms, to prevent or cure chafing. Formulas for miscellaneous toilet powders are given under this heading; other formulas follow under distinctive headings. I. Talcum av.oz. 13 Wheat starch av.oz. 1 y 2 Salicylic acid dr. 2> l / 2 Reduce all to very fine powder, mix well, and pass through a fine sieve. This is the Salicylated Powder of Talc of the Germ. Pharm. The correspond- ing preparation of the N. F. has boric acid instead of wheat starch. II. Talcum av.oz. 16 Oil of rose drops 10 Oil of wintergreen drop 1 Essence of jasmine dr. 3 Mix well and pass through a fine sieve. III. Precipitated chalk... Talcum Orris root Boric acid Essence of cassie... Essence of jasmine White rose extract.. The chalk should be the so-called English variety; the talcum, orris, and acid should be in very fine powder. The whole should be well mixed and then passed through a fine sieve. av.oz. 16 av.oz. 3 av.oz. 1 av.oz. I fl.dr. 1 fl.dr. I fl.dr. I IV. Talcum av.oz. 8 Corn starch av.oz. 8 Oil of neroli drops 30 Oil of ylang ylang drops 30 Prepare Tike the preceding. Synthetic oils may be used for this powder. V. Zinc oxid av.oz. 4 Corn starch av.oz. 4 Boric acid av.oz. 4 Talcum av.oz. 4 Oil of rose geranium drops 10 All the solids should be in fine pow- der; the whole should be well mixed, and then passed through a fine sieve. Borated Talcum Toilet Powder. This consists mostly of powdered tal- cum with some powdered boric acid. The perfume is usually some form of rose but other kinds may be employed. The talcum used for these powders should be the finest and whitest grade obtainable, should be thoroughly mixed with the other ingredients, and should be passed through a very fine sieve. VI. Talcum av.oz. 14^ Boric acid av.oz. 1 Yz Carbolic acid drops 50 The talc and boric acid should be in the finest possible powder, should be well mixed with the carbolic acid, and then should be sifted through a fine sieve. VII. Talcum av.oz. 14 Boric acid av.oz. 2 Oil of rose geranium fl.dr. 2 Prepare like the preceding. VIII. Talcum av.lb. 1 Mangnesium carbonate av.oz. 2 Borac acid av.oz. Y\ Prepare like No. I and perfume as desired. IX. Talcum av.oz. 3 Boric acid av.oz. 2 Zinc oleo-palmitate av.oz. 1 Reduce all to very fine powder, mix well, and pass through a fine sieve. FACE AND SKIN PREPARATIONS. 965 The objection to this powder is that the zinc compound becomes rancid. X. Zinc oleate av.oz. 4 Boric acid av.oz. 4 Corn starch av.oz. 8 Oil of rose drops 10 The zinc oleate and boric acid must be in very fine powder and must be well mixed with the other ingredients. The whole must then be passed through a fine sieve. This powder is liable to become ran- cid owing to decomposition of the zinc compound. Oxygen Talcum Powder. The active agent of the so-called "oxygen talcum powders" is sodium per- borate, which on contact with moisture evolves oxygen. In its simplest form, an oxyp-en talcum powder may be made as follows: XL Talcum av.oz. 19 Sodium perborate av.oz. I Perfume, to suit. The talcum and perborate should be in very fine powder, should be well mix- ed with the perfume, and the mixture should be passed through a fine sieve. Any of the other formulas for bor- ated or violet talcum powders may be used, but the mixture should not con- tain more than about 5% of the per- borate. In the case of the borated powders, the perborate should replace the boric acid to make an oxygen pow- der. Violet Talcum Powder. Any of the borated talcum powders may be converted into a violet talcum powder by substituting powdered orris root for the boric acid and scenting the mixture with violet perfume in some form such as ionone solution, essence of violet, or violet extract. Or the mix- ture, or violet essences, etc., used to make violet extract may be used for perfuming the powder. XII. The following contains both orris and boric acid: Talcum av.oz. 9 Boric acid av.oz. 2 Orris root av.oz. 1 Mix all in fine powder and pass through a fine sieve. Violet extract or ionone may be added. Poudre de Vicomtesse. XIII. Mme. Qui Vive's formula: Talcum, powder av.oz. 12 Starch, finest av.oz. 2 Orris root, powder av.oz. 2 Oil of orris drops 16 Violet Toilet Powder. The following formulas are recom- mended for making so-called "violet toilet oowder." Their resemblance in odor to violets is, however, not very marked. Orris root is present in all these powders which improves the odor. XIV. Wheat flour or corn starch. av.oz. 24 Orris root, powder av.oz. 2 Oil of lemon drops 20 Oil of bergamot drops 20 Oil of neroli drops 10 Oil of bitter almond drop 1 Tincture of musk m. 30 Mix well and pass through a very fine sieve. XV. Corn starch av.oz. 16 Orris, powder av.oz. 1 Oil of rose drops 2 Oil of lavender flowers drops 4 Oil of bergamot drops 15 Tincture of musk drops 15 Essence of violet drops 15 Prepare like the preceding. F-ice Toilet Powder. The /following formulas \contain a small proportion of rice flour combined with other valuable ingredients. Any desired perfume may be added. The whole mixture should, as in all preced- ing cases, be in very fine powder and should be sifted through a very fine sieve. XVI. Rice flour av.oz. 4 Corn starch av.oz. 12 Perfume, to suit. 966 THE STANDARD FORMULARY XVII. Talcum av.oz. i Boric acid av.oz. 2 Zinc oxid .av.oz. 3 Rice flour av.oz. 8 Perfume, as desired. Puller's Earth Nursery and Anti- Chafe Powder. XVIII. Fuller's earth av.oz. 10 Talcum av.oz. 3 Corn starch av.oz. 3 Perfume, if desired. XIX. Fuller's earth av.oz. 6 Corn starch av.oz. 6 Talcum av.oz. 2 Boric acid, powder av.oz. 1 LIP SALVES OR POMADES. These are preparations for anointing the lips to cure or prevent "crackine." They consist usually of white or yel- low wax, spermaceti, paraffin, cocoa but- ter, petrolatum, or lard mixed with an oil like olive or sweet almond, the whole being flavored, usually with oil of rose. Frequently they are tinted a rose color by means of carmine, alkannin, or alkanet root. The first mentioned must first be triturated to very fine powder before adding oil or fat, and during cooling the fatty mixture must be frequently stirred to prevent it from subsiding. Alkannin is easier to use be- cause it dissolves in the fats. Alkanet colors the fatty mixture during a rather prolonged maceration assisted by heat. If a colored preparation is to be made, yellow wax should be substituted for white wax, wherever the latter is men- tioned, owing to the better keeping qual- ities of the former. Camphor may be added to these preparations, also sali- cylic acid. The preparations are usually known by such titles as "rose lip salve," "tulip salve," "lip pomade," "rose cerate," "lip ointment" and "coral lip salve." Lip salve is dispensed in very small jars. I. White wax av.oz. 1 Sweet almond oil fl.oz. 2 Carmine gr. 1 Oil of rose droo 1 Melt the wax, add the sweet almond oil, triturate the carmine to very fine powder, mix intimately with the fats, and then incorporate the oil of rose. This is the formula of the French Codex : II. White wax av.oz 1 Spermaceti -av.oz. 1 Liquid petrolatum fl.dr. 6 Tincture of benzoin fl.dr. 2 Alkanet root, bruised dr 2 Oil of rose drops 5 Melt the wax and spermaceti, add the liquid petrolatum and the root, macer- ate the latter with the melted fats for about one-half hour, strain, allow to cool somewhat, and incorporate the tincture and oil. III. Paraffin wax av.oz. 2 White petrolatum av.oz. 4 Alkanet root dr. I Camphor dr. 1 Menthol dr. 1 Eucalyptol m. 15 Oil of bitter almond droos 4 Oil of clove drops 2 Oil of cassia drop 1 Digest the root in the melted paraffin and petrolatum, strain, add the other ingredients, stir well, and put into jars or boxes. IV. Cocoa butter av.oz. 2 White wax dr. 2 Mix by fusion and perfume to suit. V. Cold cream av.oz. 4 Glycerin fl.dr. 2 Tincture of benzoin fl.dr 1 Carmine sufficient to color Rub the carmine with the glycerin, and incorporate with the cold cream; then add the tincture of benzoin and rub the ointment until the alcohol of the tincture has evaporated. FACE AND SKIN PREPARATIONS. 967 IT. Dr. Unna's usual treatment consists of applications of the following at night, to be washed off the following morn- ing: Acetic acid fl.dr. 2 Petrolatum . . av.oz. 2 Wool-fat, anhydrous av.oz. 2 Hydrogen peroxid .fl.oz. 2 The acetic acid is sometimes omitted and the hydrogen peroxid increased to 4' fluidounces. III. Unna also recommends the following : Ichthyol 1. .av.oz. 2 Pea flour dr. 6 Wool-fat, hydrous dr. 3 Sweet almond oil dr. 3 Water .. ....... fl.dr. 3 Mercuric chlorid gr. 2 Dissolve the mercuric chlorid with the water and incorporate this solution with the other ingredients. The pea flour is added to give consistency to the mixture and may be replaced by wheat flour. IV. Dr. Ohman-Dumesnil advises this treatment : Force out the contents with an ex- tractor (a small watch key will answer) every day, then apply hot water, follow- ed by the following ointment : Sulphur, washed dr. ^ to 1 Oleate of mercury gr. 30 Cold cream av.oz. 1 Apply this at night. If used after the hot water applica- tion, the following ointment, thoroughly rubbed in, will be found efficient : Resorcin gr. 12 Cold cream av.oz. 1 Apply at night also. When the comedones are small but in great numbers, the following is a good application : Acetic acid, diluted fl.oz. I Glycerin fl.oz. 2 Kaolin av.oz. 3 Apply at night also. Hot water here means water from no to 120° F. VI. Carmine, fine powder -. ..gr. 5 Glycerin fl.dr. 2 Cold cream . . av.oz. 4 Rub the carmine with the glycerin and intimately mix with the cold cream. If not the shade to suit, more or less carmine may be used This and the preceding preparation may be entitled "rose lip cream." APPLICATIONS FOR BLACK- HEADS OR COMEDONES. Blackheads, or comedones, are due to the solidflcation of the natural fat within the sebaceous glands or ducts. The skin under these circumstances lacks expulsive energy to get rid of the thickened secretion. The application of very hot water and wool-fat soap often suffices to remove the trouble. To keep the skin in a healthy condition, bath- ing and washing must be freely prac- ticed and must be stimulated by friction with crash or Turkish towels. Alka- line soaps should be avoided. Other treatments are given below. I. Before retiring bathe the parts af- fected with very hot water, dry well, then rub thoroughly with a lotion con- sisting of Ether • .fl.oz. 1 Alcohol ..fl.dr. 6 Aromatic spirit of ammonia. fl.dr. 2 The object of this, is to dissolve the sebaceous deposits. To further soften and loosen the same, a paste is applied, composed of Acetic . acid fl.oz. 1 Glycerin fl.oz. 1 ^2 Kaolin ..''. .av.oz. 2 Perfume .to suit This paste is removed by washing the face on the following morning. After a few days the comedones can be easily expressed, if necessary, with the aid of a watch key. Friction with a Turkish towel, the use of soap containing tar, resorcin or ichthyol rubbing with resorcin solu- tion in spirit of ether, etc., constitute a good after treatment. 968 THE STANDARD FORMULARY Dr. McCasey's treatment . Ammonium carbonate dr. I Water fl.oz. 3 Ether fl.oz. 3 Apply several times daily. This mixture is much improved pharmaceutically by dissolving the am- monium carbonate, adding 3 fluidounces of alcohol, and then mixing with the ether. VI. Mme. Qui Vive's sulfur paste for blackheads is as follows : Potassium carbonate av.oz. 1*4 Precipitated sulfur av.oz. \Y\ Water fl.dr. 3 Alcohol fl.oz. 1 Glycerin fl.oz. I Ether fl.dr. 13 Apply at night and bathe the face the next morning. FRECKLE AND MOTH REMOVERS. Freckles consist of deposits of pig- ment in the skin. There are two kinds of freckles, one caused by exposure to the sun and heat of summertime and is therefore akin to tan or sunburn; this kind is called "summer freckles." This kind may fade away by itself and is easily removed by applications. The other is a permanent pigmentation of the skin, the true freckle, also called "cold or winter freckle." "Summer freckles" may be removed by the same remedies as are recom- mended for sunburn, while true freckles require more active agents. Most of the preparations recommended for freckles have as a base some agent of an escharotic action like citric acid (or lemon juice) or a mercurial salt like mercuric chlorid or ammoniated mer- cury (white precipitate), the former being usually recommended, the latter more safe. These agents destroy and remove the outside old skin, mercuric chlorid acting most nuickly but also most dangerously. Another agent rec- ommended is zinc sulfocarbolate. Lat- terly hydrogen peroxid is suggested and probably sodium perborate would prove useful. The same applications are used to eradicate moths. Most of the formulas mentioned be- low are highly recommended for the purpose, in many cases having received the approval of medical authority. I. Borax dr. 5 Potassium chlorate dr. 5 Alcohol fl.oz. 1 Glycerin fl.oz. 2 Rose water, to make fl.oz. 16 Dissolve the two salts in the liquids and filter. This is to be applied with a soft sponge several times a day. It forms a mild harmless lotion and frequentl- answers completely in mild cases. The same remarks apply to the next prepa- ration. II. Sodium sulfocarbolate gr. 50 Glycerin fl.oz. 2 Rose water fl.oz. 1 Alcohol fl.oz. 1 For directions, see No. I. III. Salicylic acid gr. 60 Bay rum fl.oz. 4 This is to be applied night and morn- ing with a soft cloth or sponge. This lotion soon produces a slight roughness of the skin, which should be subdued by the use of glycerite of starch or any toilet cream cr jelly. Care must be taken not to get any of it too near the eyes, nostrils and lips. Should the skin become red and irri- tated, the lotion must be suspended for a few days to allow the inflammation to subside. IV - . Mercuric chlorid gr. 5 Hydrochloric acid m. 100 Bitter almonds dr. 5 Glycerin fl.dr. 3 Tincture of benzoin fl.dr. 1 Orange flower water, to make fl.oz. 8 Blanch the almonds and, in the usual manner for making seed emulsions, pre- FACE AND SKIN PREPARATIONS. 969 pare 6H fluidounces of emulsion, and to this add the tincture and glycerin. Also dissolve the mercuric chlorid in I fluidounce of water, add the acid, and incorporate this solution with the emul- sion. This liquid is to be applied once a day with a sponge or soft cloth. V. Ointment of ammoniated mercury av.oz. 3^ Bismuth subnitrate dr. 3 This is to be applied night and morn- ing. It is not as harsh to the skin as a mercury bichlorid preparation. VI. This is similar to the preceding: Ammoniated mercury dr. I Bismuth subnitrate dr. 1 Cold cream av.oz. 4 Apply at night. VII. Chloral hydrate dr. 3 Carbolic acid m. 90 Tincture of iodin gr. 90 Glycerin fl.oz. i x / 2 This is to be applied at night with a small brush. VIII. Wool-fat, hydrous av.oz. 1 Sweet almond oil fl.oz. 1 Precipitated" sulfur av.oz. 1 Zinc oxid dr. 4 Perfume, to jsuit. Apply this ointment to the face at night, wash it off in the morning, and apply the following lotion several times during the day : Solution of potassa fl.dr. 4 Distilled water, to make. . .fl.oz. 10 IX. Hydrogen peroxid fl.oz. 2 Water fl.oz. 2 Distilled extract of witch hazel fl.oz. 4 This is to be applied several times a day. Rose or orange flower water may be used in place of the water and witch hazel. X. Gowland's Cosmetic Lotion, see, is also used for freckles. Most of the remedies recommended for "tan" may also be used against "summer freckles." REMEDIES FOB PIMPLES OR ACNE. Like "blackheads," pimples is a dis- ease of the sebaceous glands, and is characterized by an eruption which us- ually appears on the face but may occur on the back, shoulders and chest. The cause may be local, such as lack of per- fect cleanliness, the use of strong alka- line soaps, but the affection is usually the result of constitutional disturbance and manifests itself mostly during the periods of puberty and adolescence. The most common cause is some form of indigestion and the main reliance for cure should be upon dieting. Greasy foods, sweet stuffs, such as pie, cake, candy, etc., hot bread and biscuits, cheese, highly seasoned foods, etc., should be avoided. Internal medication with the view of exercising a direct effect upon the dis- ease consists in the use of calcium sulfid and of arsenic, ichthyol also have been recommended. Calcium sulfid is given in doses of % grain 3 or 4 times a day, arsenic in doses of 1/20 grain 3 times a day, and ichthyol 5 to 8 grains 3 times a day. Local treatment should consist, first and foremost, of the frequent use of very hot water and good toilet soap. In mild forms this may be sufficient. In severer forms, tincture of green soap should be used to cleanse the skin. Gen- erally, however, more energetic treat- ment is required. The formulas men- tioned below are all highly recommend- ed for the purpose. I. Mercuric iodid gr. 3 Potassium iodid gr. 20 Sodium bicarbonate ...gr. 20 Aromatic spirit of ammonia.. m. 30 Bay rum fl.oz. I Camphor water, to make. . .fl.oz. 4 Apply once or twice a day with a sponge or soft cloth. 970 THE STANDARD FORMULARY II. Zinc sulfate dr. i to 4 Potassium sulfuret dr. 1 to 4 Precipitated sulfur dr. 1 to 4 Rose water fl.oz. 4 Dissolve the zinc sulfate and potas- sium sulfuret separately in half the rose water, then mix the solutions, and rub up with the sulfur. This lotion should be applied fre- quently. It is best to begin with a weaker preparation, gradually making it stronger so as not to produce irritation of the skin. If there is any irritation, some toilet cream or emollient should be applied for a day or two. III. Ichthyol av.oz. y 2 Zinc oxid av.oz. 1 Starch av.oz. 1 Petrolatum av.oz. V/2. Thoroughly steam the face at night or wash it in water as hot as can be borne. All pustules and "blackheads" should be opened and emptied with as little vio- lence as possible. After careful drying of the face, the above paste should be thoroughly rubbed into the affected spots. In the morning bathe the face with a bland soap and cool water, dry- ing with little friction. IV. This is Unna's paste for pim- ples : Resorcin av.oz. x /z Zinc oxid av.oz. 1 Starch av.oz. 1 Petrolatum av.oz. 2 APPLICATIONS FOR TAN OR SUNBURN. "Tan" is a darkening of the skin due to exposure to the sun. When the ex- posure is of such a nature as to cause pain or smarting and peeling of the skin, the result is properly called "sunburn." An excellent remedy to allay the smart- ing of sunburn is lead water. Other soothing and healing remedies for sun- burn are any of the cold creams, toilet creams or jellies, creams containing al- monds, camphor ice, skin emollients or toilet tablets. To bleach a tanned skin, any of the preparations recommended for freckles may be used, also the prep- arations enumerated under the heading Face or Skin Bleaches or Whiteners, also Gowland's Cosmetic Lotion. The preparations mentioned below emanate mostly from good authority. I. Under the name Albadermine has been devised a foreign process for the removal of tan, sunburn, and summer freckles which requires the use of two solutions : Solution A. Potassium iodid dr. 2 Iodin gr. 6 Glycerin fl.dr. 3 Infusion of rose fl.oz. 4 Dissolve the potassium iodid in a small quantity of the infusion and one fluidram of the glycerin; with this fluid moisten the iodin in a glass mortar and rub it down, gradually adding. more li- quid until complete solution has been obtained; then stir in the remainder of the ingredients, and bottle the mixture. Solution B. Sodium hyposulfite dr. 4 Rose water fl.oz. 16 Dissolve and filter. With a small camel's hair oencil or piece of fine sponge apply a little of "A" to the tanned or freckled surface, until a slight but tolerablv uniform brownish- yellow skin has been produced. At the expiration of fifteen or twenty minutes moisten a oiece of cambric, lint or soft rag with "B" and lay it upon the affect- ed part, removing, squeezing away the liquid, soaking it afresh, and again ap- plying until the iodin stain has disap- peared. Repeat the entire process three times daily, but diminish the frequency of the application if tenderness be pro- duced. In the course of from three or four days to as man}' weeks the discol- oration will either have disappeared en- tirely, or its intensity will be very great- ly diminished. "Summer freckles" are said to yield readily to this treatment. II. Borax, powder dr. 4 Zinc oxid dr. 4 Glycerin fl.oz. 2 FACE AND SKIN PREPARATIONS. 971 Bay rum fl.oz. 2 Distilled water fl.oz. 7^ Dissolve the borax in the water and add the other ingredients. Apply freely 5 or 6 times a day. III. Hydroquinone . gr. 100 Glacial phosphoric acid gr. 60 Glycerin fl.oz. 1 Water, to make fl.oz. 8 Apply twice daily, first washing and drying the skin carefully. FOR MOTH OR LIVER PATCHES. The cause of these pigmentations of the skin is unknown but they are ascrib- ed by the laity to affections of the liver, whence the name. The preparations recommended for freckles and for tan will also be useful for moth patches, es- pecially the preparation known as "alba- dermine." The following is also rec- ommended : Zinc oxid dr. 3 Magnesium carbonate dr. 3 Kaolin dr. 6 Glycerin dr. 6 Wool-fat, hydrous .av.oz. 2 Apply to the discolored spot as often as convenient. WRINKLE CREAM. The following is offered by a beauty expert under the above name: White wax av.oz. 2 Spermaceti av.oz. 2^ Wool-fat, hydrous av.oz. 7 Sweet almond oil fl.oz. 16 Rose water fl.oz. 12 Borax, powder gr. 80 Of course this is only a "cold cream" and any other preparation of the same kind containing wool-fat may be used for the same purpose. See also the fatty massage creams and skin foods. WRINKLE LOTIONS. Washes for preventing the formation of wrinkles are usually of an astringent nature. They ward off the wrinkles but they close the pores of the skin and eventually impart to the latter a dead- ened appearance. The following are used : Tannic acid dr. 1 Alcohol fl.dr. 1 Glycerin fl.dr. 2 Water fl.oz. 4 Apply this 3 times a day. II. Alum dr. 1 Glycerin fl.dr. 4 Water, to make fl.oz. 8 Use like the preceding. III. It is said that there is nothing better for the skin than wool-fat and if used daily it unquestionably keeps the skin soft. Or any of the "cold creams" or any other toilet preparation contain- ing wool-fat may be used. The follow- ing is also a good lotion for this pur- pose : White castile soap dr. 2^ Borax dr. iy 2 Cocoanut oil dr. 3 Wool-fat, hydrous av.oz. 1 Water ..fl.oz. 1 Rose water fl.oz. 10 Rub the soap and borax, both in fine powder, with the oil, fat and water un- til thoroughly mixed, then gradually in- corporate the rose water, which has pre- viously been warmed. ASTRINGENT WASH, Mme. Qui Vive's. Cucumber juice fl.oz. 3 Cologne water fl.oz. 2 Tincture of benzoin fl.oz. 1 Elder flower water, to make. fl.oz. 16 This is recommended for coarse pores and oily or flabby skin. It is to be ap- plied with a soft sponge night and morning. LOTION FOR SWEATY HANDS. When the hands sweat inordinately so as to interfere with work, the following applications may be used : Boric acid dr. 2 Borax dr. 3 Salicylic acid dr. 3 Glycerin fl.oz. 3 Bay rum fl.oz. 3 Apply to the hands 3 times a day. 972 THE STANDARD FORMULARY IT. Boric acid dr. V/z Borax av.oz. l / 2 Salicylic acid av.oz. l / 2 Glycerin fl-oz. 3 Alcohol fl.oz. 3 Use like the preceding. FOR RED HANDS. Liebreich recommended the following preparations : T. Wool-fat, hydrous av.oz. 1 Vanillin gr. 6 Oil of rose drops 4 II. Wool-fat, hydrous dr. 2 Liquid paraffin dr. s J / 2 Vanillin gr. 2 Oil of rose drop 1 These preparations are to be used fre- quently. They coat the skin with a thin layer of fat which prevents Assuring of the cuticle. 1 FOR "COLD SORES." These are a cluster of vesicles which occur at the corners of the mouth or the borders of the lips. There is red- ness, swelling, and a sense of tingling and burning. Various substances rec- ommended are glycerite of tannin, zinc ointment, and preparations containing camphor, such as camphor ice. Lassar's paste is also excellent. A coating of flexible collodion protects the parts and relieves the symptoms. The following dusting powder is good : Boric acid gr. 15 Acctanilid gr. 15 Starch dr. 4 "Cold sores" are said to disappear after a mild cathartic taken for 2 or 3 days. WART ERADICATORS. Pharmacists are frequently called upon to recommend or offer some rem- edy for the eradication of the peculiar excrescences known as warts. These are peculiar in that sometimes a very simple remedy applied but once or twice will cause them to disappear and at other times they persist indefinitely in spite of all treatment. Every one is probably familiar with the application of silver nitrate in sticks, concentrated nitric acid, creosote, car- bolic acid, or salicylic acid in any of the forms of corn cures. Glacial acetic and dichloracetic acid are frequently em- ployed, while some add salicylic acid in the proportion of 1 in 16 to concentrated acetic acid. Another escharotic solution consists of chromic acid 1 part, water 5 parts. Unna recommends mercurial plaster containing 5% of arsenic. It is also recommended to shave off the wart to the quick and then to apply a com- press wet with a saturated solution of ammonium chlorid. A corrosive collo- dion for warts consists of 1 part of mercuric chlorid dissolved in 20 parts of collodion. Other applications are: Concentrated hydrochloric acid, solu- tion of antimony chlorid, solution of mercuric nitrate, potassium bichromate, arsenic oleate, copper oleate, and for- maldehyde. Castor oil and oil of cinna- mon are also useful. All of these rem- edies must be applied once or twice daily until the wart disappears. The outer hard, thick layer of cuticle should always be removed before applying any- thing whatever. An ointment sometimes recommended is the following: Verdigris gr. 50 Savin, powder gr. 50 Soap cerate av.oz. 1 The following powder is said to be very effective: Calomel gr. 30 Boric acid gr. 15 Salicylic acid gr. 5 Cinnabar gr. 3 Rub into the wart 2 or 3 times a day. Or use the following: Mercuric chlorid gr. 5 Salicylic acid dr. 1 Collodion fl.oz. 1 In the case of multiple warts, where a large number appear within a short time, there is some constitutional de- rangement, and the patients are usually advised to take Fowler's solution in very small doses, or magnesium sulfate in 5 HAIR AND SCALP PREPARATIONS. 973 gr. doses 3 times daily. The following application has been recommended: Sublimed sulfur dr. 2 Glycerin . , fl.dr. 5 Acetic acid fl.dr. 1 Apply repeatedly to each wart, contin- uing the treatment for several days. The warts dry up and then drop off. A medical journal recommends the following : When warts persist it is well to give about 8 grains of magnesium sulfate each night; and a local application of Chloral hydrate dr. i l / 2 Salicylic acid dr. 1 Acetic acid fl.dr. V/ 2 Ether fl.dr. 1^ Collodion fl.dr. 4 Paint on the warty growths once daily. Children's warts, appearing principally on the hands, may be removed by ap- plying during several days solution of soda or potassa, and then covering them with collodion containing tannin. The same treatment applies for common warts. Erasmus Wilson considers the appli- cation of caustic potassa in stick form to be the quickest and most reliable eradicator, one treatment being all that is usually required. Warts appearing on the skin of elder- ly persons must be looked upon' as sus- picious (cancer) and should be shown to a reliable surgeon. MISCELLANEOUS COSMETIC PREPARATIONS. Under this heading are grouped a number of preparations which are de- manded occasionally and cannot appro- priately be classed under any other heading. Kummerfeld's Cosmetic Water. Sublimed sulfur gr. 45 Glycerin fl.oz. 1 Spirit of camphor fl.dr. 3 Spirit of lavender fl.dr. 3 Cologne water fl.oz. 1 Distilled water fl.oz. 12 This is used as an application for a blotched skin. Lily Water. A. — Eau de Lys de Lohse. This was found to consist of Zinc oxid g. 2 Talcum g. 2 Glycerin g. 4 Rose water g. 200 B. — Eau de Lys de Paris. This was found to consist of Bismuth subnitrate g. 35 Rose water g. 300 Hebra's Cosmetic Liniment. Precipitated sulfur av.oz. 2 Potassium carbonate av.oz. 2 Glycerin fl.oz. 1 ^ Ether fl.oz. 2^ Diluted alcohol fl.oz. 2 This is recommended for "blackheads" and for eruptions of the skin. Lilionese. Borax dr. 3 Potassium carbonate gr. 45 Talcum av.oz. 1 V\ Cologne water fl.oz. i l / 2 Rose water fl.oz. 4 Orange flower water fl.oz. 4 This is recommended for pimples, "blackheads," etc. CHAPTER III. PREPARATIONS FOR THE HAIR, SCALP, MUSTACHE AND BEARD. LIQUID SOAPS. These are solutions of soap in a mix- ture of water and alcohol and are gen- erally prepared by direct combination of fixed oil or oleic acid with alkali in the presence of water and alcohol, the latter facilitating combination. Ex- cess of alkali is necessary but great excess should be avoided. These prepa- ration are used for cleansing the skin for cosmetic and surgical purposes. If used for cleansing the skin prior to per- forming surgical operations they may contain ether or various antiseptics may be added such as carbolic acid or a cresol solution. For cosmetic purposes they may be scented with different volatile oils or synthetic perfumes, or rose or orange flower water may be substituted for a 974 THE STANDARD FORMULARY portion or all of the water. Distilled water should be used instead of ordin- ary hydrant water as the latter usually contains various salts, particularly cal- cium, which will unite with the oil or oleic acid form insoluble oleates. These preparations may remain un- colored or they may be tinted reddish with tincture of cudbear or green with alcoholic solution of chlorophyll. The soda and potassa (sodium and potassium hydrate or hydroxid) used in these preparations should be of the strength required by the U. S. P.; if not, proportionately more must be used. I. Wilbert's formula : Cottonseed oil fl.oz. 12 Sodium hydrate av,oz. 1 Potassium hydrate av.oz. 1 Alcohol ..." fl.oz. 6 Distilled water, to make. .. .fl.oz. 60 In a suitable container, preferably a glass-stoppered bottle, dissolve the po- tassium and sodium hydrates in 6 fluid- ounces of distilled water, add the alco- hol, and then add the oil in three or four portions, shaking vigorously after each addition. Continue to agitate the mixture occasionally until saponification is completed. Then add the remainder of the water. The two hydrates must be of the strength demanded by the U. S. P. or proportionately more must be used. Dis- tilled water should be used as ordin- ary water contains salts of various kinds. The product may be medicated if desired, or it may be perfumed with volatile oils or synthetic perfumes or orange flower or rose water may be used instead of distilled water. II. Stanislaus' formula : Soft soap av.oz. 22 x / 2 Alcohol fl.oz. gy 2 Tincture of cudbear fl.oz. 1 Oil of orange fl.dr. 4 Oil of lavender flowers fl.dr. 4 Oil of bergamot fl.dr. 4 Oil of cinnamon fl.dr. 4 Water, to make fl.oz. 64 Mix in the order given here, agitate occasionallv until the soap is dissolved, and filter if necessary. The tincture of cudbear may be omitted or it may be replaced with chlorophyll. Other vo- latile oils or synthetic perfumes may be used. The soft soap for this prepa- ration should be made as follows : Linseed oil, raw av.oz. 15 Solution of potassium hy- droxid, U. S. P... av.oz. 3, gr. 20 Alcohol fl.oz. 6 Distilled water fl.oz. 7 l / 2 Mix in a half-gallon wide-mouthed bottle, adding the solution to the oil, and then incorporating the alcohol and water. Shake frequently during 24 hours until the oil is saponified. III. Cottonseed oil fl.oz. 20 Sodium hydrate av.oz. 3 Potassium carbonate dr. 5 Alcohol fl.oz. 20 Distilled water fl.oz. 22 Dissolve the sodium hydrate in half the water, add the oil and 15 fluid- ounces, agitate frequently until the oil is saponified, then add the alcohol and the potassium carbonate dissolved in the remainder of the water. IV. Oleic acid, commercial fl.oz. 14 Solution of potassium hydrate in water (iini), sufficient Alcohol fl.oz. 6 Oil of lavender flowers. . .fl.dr. 1 Distilled water, to make fl.oz. 60 Mix the acid and alcohol and neutral- ize with the potassa solution of which about 3 fluidounces will be required, using ohenolphthalein as the indicator. Then allow the liquid to become cool, add the oil and enough water to make 60 fluidounces. V. Olive or benne oil fl.oz. 24 Potassium hydrate av.oz. 6 Alcohol fl.oz. iY 2 Water sufficient Dissolve the potassium hydrate in an equal quantity of water; mix this solu- tion with the oil and alcohol, and agitate frequently until the oil is saponified, then dilute with an equal quantity of water. HAIR AND SCALP PREPARATIONS. 975 VI. Cocoanut oil av. or fl.oz. 16 Oleic acid, pure fl.oz. 8 Potash av.oz. 8 Potassium carbonate dr. 5 Water fl.oz. 24 Alcohol fl.oz. 16 Mix all, agitate frequently until the oil and acid are saponified, then decant from any undissolved potash. The potash may be caustic potassa or any good commercial grade of potash or lye. The excess will remain at the bottom of the bottle and the soap may be decanted. Liquid Glycerin Soap. Any of the previously mentioned liquid soaps, if made from fixed oil, contain some glycerin, but by a liquid glycerin soap is usually understood a liquid soap containing a fairly large proportion of glycerin. Any of the above liquid soaps may be converted into a glycerin soap by replacing a portion of the water with glycerin. The propor- tion of the latter may be varied to suit different ideas or requirements. Liquid Tar Soap. This may be prepared by adding oil of tar to the finished soap instead of perfume, in the proportion of about an ounce or two to the gallon or pine tar itself may be added to the fixed oil before saponification. SHAMPOO LIQUIDS. These are preparations used as appli- cations to the head for the purpose of removing dust, dirt, dandruff, etc., from the hair and scalp. They should be ap- plied freely and rubbed in thoroughly until a copious lather is formed which is to be removed with running water. Any of the previously mentioned linuid soaps may be used as shampoos or any of the preparations mentioned be- low. The Sea Foam Liquids which follow are somewhat different from these shampoo liquids. Potassium carbonate av.oz. 1 Borax , . . av.oz. 1 Water fl.oz. 32 Mix and dissolve. II. Soft or green soap av.oz. 1^ Potassium carbonate av.oz. 2^2 Alcohol fl.oz. 4' Water fl.oz. 26 Dissolve the soap and potassium car- bonate in the water and add the alco- hol. III. White castile soap av.oz. 1 Potassium carbonate .dr. 1 Borax dr. 2 Cologne water fl.oz. 2 Bay rum fl.oz. 2 Water, to make fl.oz. 32 Dissolve the soap in the water by the aid of heat, occasionally replacing water lost by evaporation, in the solution dis- solve the borax and potassium carbon- ate, then add the cologne water and bay rum, and filter. Egg Shampoo Liquids. IV. Yolk of 4 eggs. Spirit of soap, N. F fl.oz. 3^ Ammonia water fl.dr. 3 Oil of lemon m. 45 Oil of rose geranium .m. 15 Water fl.oz. 27 Beat the egg-yolk, mix thoroughly with the other ingredients by agitation, and strain. V. Fresh eggs 3 Spirit of soap, N. F fl.oz. i l / 2 Potassium carbonate dr. 2 r / 2 Ammonia water fl.dr. 3 Oil of rose drops 2 Oil of bergamot drops 2 Oil of rose geranium drop I Oil of bitter almond drop 1 Rose water fl.oz. 27 Thoroughly beat the eggs, dilute with the rose water, add the other ingredi- ents, mix intimately by agitation, and strain. VI. Whites of 3 eggs. Borax av.oz. 9T6 THE STANDARD FORMULARY Glycerin fl.oz. I Bay rum fl.oz. 16 Water fl.oz. 16 Beat the egg-yolk thoroughly, incor- porate with a portion of the water, dis- solve the borax in the remainder of the water, mix all the ingredients, and strain. Tar Shampoo Liquid. Add oil of tar to any of the preced- ing shampoo liquids or use one of the following : VII. Green or soft soap av.oz. 12 Potassium carbonate av.oz. 2 Oil of tar fl.dr. 2 Alcohol fl.oz. 16 Water, to make fl.oz. 64 Mix all and dissolve, let stand a few days, and filter. VIII. Pine tar av.oz. 2 l / 2 Linseed oil, raw fl.oz. 27 Caustic potash av.oz. 6 Alcohol fl.oz. 3 Water fl.oz. 30 Heat the tar and oil to 6o° C, dis- solve the potash in the water, mix with the alcohol, and add this 'solution grad- ually to the oil and tar mixture, stir- ring constantly meanwhile. Continue the heat until the oil and tar are thor- oughly saponified, then add water to make one-half gallon of liquid. Tonic Shampoo Liquid. The following may be put up under this name : IX. Tincture of quillaja fl.oz. 10 Cologne water fl.oz. 4 Glycerin fl.oz. 3 Fluid extract of jaborandi. .fl.dr. 4 Quinine sulfate gr. 30 Orange flower water, to make fl.oz. 32 Dissolve the quinine in the cologne water and tincture of quillaja, add the remaining ingredients, and filter if nec- essary. SEA FOAM LIQUIDS. (Dry Sham- poos.) The difference between these and the preceding class of preparations is not a well defined one, and in fact, the difference is largely in the matter of application or use, the shampoos being employed in liberal quantities and rub- bed in vigorously to produce a copious lather, which will then require a large amount of water for removal. In the case of sea foams, or dry shampoos, a more or less volatile alkali, ammonia, for example, usually forms the prin- cipal ingredient, which foams but slight- ly, and the hair may be cleansed by rub- bing with a wet towel. These liquids may be colored yellow with tincture of curcuma, red with tinc- ture of cudbear, or green with alco- holic solution of chlorophyll. They may be perfumed in any desided manner. I. Cocoanut oil soap of good quality av.oz. 4 Potassium carbonate av.oz. 2 Oil of bay ..fl.dr. 1 Tincture of curcuma fl.dr. 1 Alcohol fl.oz. 32 Water, to make fl.oz. 64 By the aid of heat, dissolve the soap in enough water to make 16 fluidounces, add the potassium carbonate, stir till dissolved, allow to cool somewhat, add the alcohol, oil, and tincture, and finally filter. The soap for this preparation may be made like the soft soap of the U. S. P., substituting cocoanut oil for the lin- seed oil of the latter. Any other perfume or coloring agent may be used. II. Castor oil fl.oz. 1 Ammonia water fl.oz. 1 Ammonium carbonate av.oz. 1 Alcohol fl.oz. 32 Water, to make fl.oz. 64 Dissolve the oil in the alcohol, add the ammonia water, then the ammonium carbonate dissolved in the water, and agitate thoroughly. Color and perfume in any desired manner. III. Potassium carbonate dr. 4 Ammonia water fl.dr. 10 HAIR AND SCALP PREPARATIONS. 977 Tincture of cantharides . . . .fl.dr. 5 Bay rum fl.oz. 20 Alcohol fl.oz. 20 Water fl.oz. 20 Dissolve the potassium carbonate in the water, and add the other ingredients. IV. Potassium carbonate av.oz. i J / 2 Ammonium carbonate dr. 2 l / 2 Borax av.oz. i J / 2 Spirit of soap, N. F fl.oz. 1 Bay rum fl.oz. 6 Distilled water, to make, .fl.oz. 60 Dissolve the two carbonates and borax in the water, and add the other ingredients. SHAMPOO PASTE, CREAM OR JELLY. Many shampoo preparations are now put up in the form of pastes or jellies which are really soft soaps. Many of these are known by the name "egg shampoo," but some of these prepara- tions do not contain any egg, but are merely a perfumed soap. I. Cocoanut oil av.oz. 16 Potassium hydrate av.oz. 2 Potassium carbonate av.oz. 1 Oil of rose geranium drops 10 Oil of bergamot drops 30 Distilled water sufficient Melt the cocoanut oil in a porcelain or enameled-iron dish, dissolve the caus- tic potash in 8 fluidounces of distilled water, and add gradually and with con- stant stirring to the hot oil, continuing the heat and stirring until saponification is complete. Discontinue the heat, to the warm soap add the potassium carbonate dissolved in 4 fluidounces of water, stir or beat until the paste is uniformly smooth, and finally incorporate the vo- latile oils. Other volatile oils or syn- thetic perfumes may be used. II. Olive oil fl.oz. 16 Potassium hydrate av.oz. 4 Alcohol, water, each sufficient Dissolve the caustic potash in 8 fluid- ounces of water and warm the solution. Also warm the oil on a water bath, add the solution, and stir until saponification is complete, meanwhile continuing the heat. The caustic potash for this prepara- tion should be of U. S.. P. strength; if it is weaker, more of it must be used to cause saponification. If a transparent preparation is de- sired, add 8 fluidounces of alcohol to the warm soap and continue heating without stirring. The soap may be perfumed like No. I. III. White castile soap av.oz. 16 Potassium carbonate av.oz. 4 Glycerin fl.oz. 8 Oil of lavender flowers. .. .fl. dr. 2 Oil of bergamot m. 30 Water sufficient Cut the soap into fine pieces and heat it with 2 pints of water on a water bath until thoroughly softened, then add the potassium carbonate, and con- tinue the heat until the latter is dis- solved. Occasionally add hot water to make up for that lost by evaporation. Then allow to cool somewhat, incorpor- ate the oils, and then add enough water to reduce to a suitable creamy consist- ence. Tar Shampoo Paste.- Nos. I or II may be converted into tar shampoo pastes by adding oil of tar to the fixed oil before saponifica- tion. SHAMPOO POWDERS. These are powdery mixtures which are used for washing the hair and scalp. They may be perfumed in any desired manner. They may be dispensed in small boxes or in envelopes, each one to be sufficient for one shampoo, or they may also be put up in 2 to 4-ounce perforated screw-cap jars. I. Granulated soap av.oz. 2 Borax, powder dr. 2 Potassium carbonate dr. 1 Sodium bicarbonate dr. 1 Oil of rosemary drops 20 Mix well, divide into 20 powders, wrapping in waxed or paraffined paper. 978 THE STANDARD FORMULARY One powder is sufficient for one shampoo. The granulated soap is obtainable from soap manufacturers. II. Potassium carbonate av.oz. I Borax, powder av.oz. I White castile soap, powder.. dr. 2 Oil or rose geranium drops 10 III. Borax av.oz. 1 Sodium carbonate, dried. .. .av.oz. 2 Quillaja, fine powder av.oz. I IV. Borax av.oz. 6 Sodium carbonate, dried, .av.oz. 4 Oil of rosemary drops 40 2 av. ounces of powdered soap may be added to this. HAIR-DRYING POWDER. To dry the hair after washing and to remove oil it is customary to dust the hair with powdered orris root or various mixtures containing orris root which may be applied with a powder puff. The powder may be allowed to remain 10 or 15 minutes or, better, over night, and then brushed out thoroughly. The following are good formulas for these powders : I. Orris root. White corn meal, equal Darts of each. Both should be in fine powder. II. Orris root av.oz. 2 Talcum av.oz. 3 Starch av.oz. 5 Tincture of musk m. 20 Oil of lemon drops 15 Oil of bergamot drops 15 Oil of neroli drops 6 The first three ingredients should be in fine powder, and all ingredients should be well mixed. III. Wheat flour av.oz. 8 Orris root, powder av.oz. 1 Heat the flour without scorching un- til perfectly dry, then mix intimately with the orris. HAIR OILS. (Huiles Philocome.) Hair oil may be prepared from any of the bland, fixed, non-drying oils such as olive, mustard, benne, rapeseed or peanut oil, also from liquid petrolatum (paraffin oil), or from a mixture of castor oil and alcohol. These mixtures must be rendered pleasantly odorous by the addition of suitable perfume. See under Perfumes for Hair Oils and Pomades for different combinations of oils suitable for perfuming these oils. Frequently hair oil is colored red by the use of alkanet root or its color- ing constituent, alkannin. It may also be colored yellow by means of cur- cuma or brownish with annatto. Hair oil in its usual yellow condition is frequently dispensed under the name "bear's oil"; if colored red it is often known as "rose oil." Any of the preparations mentioned below may^be colored as described above or they may be left uncolored. They may also be perfumed in any desired manner. Hair Oil Containing Castor Oil and Alcohol. I. Castor oil fl.oz. 4 Alcohol '. fl.oz. 26 Tincture of cantharides. .. .fl.oz. 2 Oil of lavender flowers. .. .fl. dr. 1 Oil of rosemary fl.dr. 1 Oil of clove..'. fl.dr. 2 Oil of bergamot fl.dr. 4 Alganet root, powder dr. 2 Mix the oils in a bottle; put the alka- net root on a filter or pack in a fun- nel and percolate the alcohol through it ; mix this percolate with the oily mix- ture, and add the cantharides tincture. The alkanet may be omitted. II. Castor oil fl.oz. 16 Alcohol fl.oz. 16 Oil of nutmeg drops 30 Oil or rose drops 20 Oil or rosemary drops 10 Oil of neroli drops 10 Tincture of musk fl.dr. 1 Alkanet sufficient Prepare like No. I. The alkanet may be omitted. HAIR AND SCALP PREPARATIONS. 979 Hair Oil Containing Paraffin Oil. III. Paraffin oil fl.oz. 32 Alkanet root av.oz. x / 2 Oil of bergamot fl.dr. 1 Oil of clove drops 15 Oil of rose drops 2 Digest the paraffin oil with the alka- net root, strain, and add the volatile oils. IV. Paraffin oil fl.oz. 16 Cottonseed oil fl.oz. 8 Oil of nutmeg droos 30 Olive of clove drops 15 Oil of cassia drops 10 Benzoated Hair Oil. The benzoated oil for these hair oils may be made as follows : Benzoin av.oz. 4 Alcohol . m fl.oz. 8 Castor oil fl.oz. 4' Reduce the benzoin to coarse pow- der, macerate with the alcohol for a week or so, agitating frequently, then filter, to the filtrate add the oil, and by means of a water bath evaporate the alcohol. Each fluidounce of oil repre- sents one ounce of benzoin. V. Cottonseed oil fl.oz. 15 Benzoated oil fl.dr. 4 Oil of bergamot ...fl.dr. 1 Oil of lavender flowers m. 30 Oil of clove drops 10 VI. Expressed oil of mustard seed fl.oz. 15 Benzoated oil fl.dr. 4 Oil of lemon m. 30 Oil of cinnamon drops 15 Oil of clove drops 15 Oil of rose geranium drops 5 Burdock Boot Hair Oil. (Kletten- wurzel Haar Oel.) The following makes a preparation containing burdock root : VII. Olive or benne oil Burdock root, fresh Castor oil Oil of bergamot Oil of rose geranium. . . . Alkannin or alkanet root 62 ...fl.oz. 32 . .av.oz. 4 ...fl.oz. 2 ...fl.dr. 2 ...fl.dr. I . .sufficient Digest the olive oil or benne oil with the burdock root for about one-half hour at a moderate heat, then decant the clear liquid, add the other oils and color, if desired, with alkannin. Alkanet may be employed instead of the latter and may then be added to the burdock root during digestion. Some of the so-called "burdock root hair oils" do not contain any burdock root. Macassar Oil. True macassar oil is a fixed oil de- rived from the seeds of an East Indian plant, but this is a very scarce article and probably valueless as a hair oil and tonic. Various mixtures used for oiling the hair have been sold under this name and the following are current formulas for such mixtures. VIII. Olive oil fl.oz. 32 Alkanet root '.av.oz. 2 Or alkannin gr. 75 Oil of lemon drops 30 Oil of cinnamon drops 20 Oil of clove drops 20 Oil of rose drops 10 Digest the olive oil with the alkanet or alkannin, strain, allow to cool, and add the volatile oils. Other cheaper vegetable oils may be substituted for the olive oil. Cocoanut Oil Hair Dressing. Cocoanut oil was at one time highly extolled as a hair grower, hence its use in hair oils. The characteristic feature of these mixtures is that they deposit a portion of the cocoanut oil on cooling. IX. Cocoanut oil fl.oz. 8 Castor oil fl.oz. 6 Alcohol fl.oz. 14 Oil of lavender flowers fl.dr. 2 Oil of bergamot drops 60 Oil of rose geranium drops 20 Melt the cocoanut oil, and add it to the castor oil dissolved in the alcohol. Shake well together and add the volatile oils. X. Cocoanut oil > av.oz. 2 T < Castor oil fl.oz. 16 980 THE STANDARD FORMULARY Alcohol fl.oz. 16 Oil of lavender flowers. .. .fl. dr. 2 Oil of bergamot fl.dr. 2 Oil of white thyme m. 30 Prepare like the preceding. PERFUMES FOR HAIR OILS AND POMADES. The following mixtures may be em- ployed for perfuming oily mixtures which are intended to be used as hair oils and hair pomades. I. Oil of lavender flowers fl.oz. 1 Oil of rosemary fl.oz. 1 Oil of clove fl.dr. 2 Oil of cassia fl.dr. 1 II. Oil of bergamot fl.dr. 10 Oil of lemon fl.dr. 4 Oil of clove drops 20 Oil of orange drops 20 Oil of cinnamon drops 10 Oil of bitter almond. drops 5 III. » Oil of bergamot fl.dr. 7 Oil of rose fl.dr. 1 Oil of rose geranium m. 30 Oil of clove fl.dr. iy 2 IV. Oil of bergamot fl.dr. 5 Oil of sandalwood fl.dr. \Y 2 Oil of orris, liquid fl.dr. iy 2 Oil of clove drops 40 Oil of rose drops 20 V. Oil of bergamot fl.dr. 4 Oil of rose m. 30 Oil of cassia m 30 VI. Oil of bergamot fl.oz. 1 Oil of palmarosa fl.dr. 4 Oil of cinnamon fl.dr. 4 Oil of neroli fl.dr. 2 Eugenol fl.dr. 2 Isosafrol drops 15 Terpineol dr. 4 COLORS FOR HAIR OILS AND POMATUMS. TTair oils and pomatums may be col- ored fine red by digestion with alkanet root which yields its coloring matter readily to hot fats or oils. The degree of color may be varied by using differ- ent amounts of the root. Instead of alkanet root, it is more convenient to use alkannin, its coloring principle. It is readily soluble in hot fats. . A yellow color may be imparted to hair pomades by digesting them with powdered curcuma root or by adding palm oil. Hair oils are best colored yellow by digestion with curcuma. A brown color may be imparted to oils and pomades by digestion with an- natto. Besides the coloring substances men- tioned, there are a number of anilines that are suitable for coloring oils and pomades. These are the kind known as "oil-soluble anilines." When alkanet, curcuma or annatto are used for coloring, they should be re- duced to coarse powder, then macerated with the warmed or heated oil or pom- ade until the desired tint is obtained, stirring frequently, then straining (or filtering if necessary), and finally adding the perfume. HAIR POMADES OR POMATUMS. These preparations are made with va- rious substances such as lard, beef mar- row, cocoa butter, wax, cocoanut oil, petrolatum, ceresin, wool-fat, castor oil, olive oil, cottonseed oil, etc. To obtain a good product the various fatty ingre- dients must be in perfectly fresh condi- tion. Most of the hair pomades as now made consist of petrolatum, this being so very cheap. These fatty bodies should be rendered pleasantly odorous by the addition of perfumes or mixtures of various oils, synthetic perfumes, etc. In some of the formulas given below, the perfume is mentioned; in such as specify no per- fume, the scents or perfumes under the preceding title may be employed. Some formulas for hair pomades mention water as an ingredient. This is employed for cheapening purposes. In combining the ingredients of pom- ades, the less fusible fats, like wax or spermaceti, should be melted first, the lard, petrolatum, or fixed oil should then be added, and the whole allowed to be- HAIR AND SCALP PREPARATIONS. 981 come nearly cold before incorporating the perfume. I. Yellow wax av.oz. 4 Cottonseed oil fl.oz. 20 Lard av.oz. 5 Mix by fusion, stir until cold, incor- porating perfume with the mixture dur- ing cooling. II. Yellow wax av.oz. 2 Benzoinated lard fl.oz. ?, Castor oil fl.oz. 6 Sweet almond oil fl.oz. 1 Olive oil fl.oz. 4 Melt the wax at a gentle heat, add the oils and lard, stir till all is melted, allow to cool, stirring constantly till hard. While it is cooling any desired perfume may be incorporated. III. Yellow petrolatum av.oz. 12 Flower pomade av.oz. 3 Yellow wax av.oz. 2 Melt the wax, then add the pomade and petrolatum, and continue the heat and stir until all are melted. Allow to cool, stirring well to secure a uniform mixture. Any of the imported flower pomades may be used. The product has a fine odor. IV. White wax av.oz. 20 Sweet almond oil fl.oz. 8 Oil of bergamot fl.dr. 2 Oil of lemon fl.dr. 1 Oil of lavender flowers m. 30 Oil of clove m. 15 Melt the wax, add the almond oil, stir as the mixture cools, and incorpor- ate the essential oils. Castor Oil Hair Pomade. V. Castor oil av.oz. 16 White wax av.oz. 4 Oil of bergamot fl.dr. 3 Oil of lavender flowers drops 30 Melt the wax, add the castor oil, mix well and when nearlv cold add the re- maining ingredients. VI. Castor oil av.oz. 16 Petrolatum av.oz. 4 l A Yellow wax av.oz. 2]/ 2 Melt the wax, add the petrolatum and oil, and when nearly cold add any suit- able perfume. VII. Wax, white or yellow av.oz. 6 Castor oil av.oz. 10 Cottonseed oil av.oz. 4 Melt the wax, add the other ingredi- ents, and stir until cool. Suitable per- fume may be added. Cocoanut Oil Hair Pomade. VIII. Lard av.oz. 3 Cocoanut oil av.oz. 12 Ceresin, white av.oz. 3 Borax dr. 2 Distilled water fl.oz. 12 Melt the ceresin at a gentle heat, add the lard and oil, add the previously warmed water containing the borax in solution, and stir until congealed. The pomade may be perfumed if desired. Crystal Hair Pomades. (Transparent Pomades.) Under this heading are grouped hair pomades which are made to assume a crystalline appearance. They are also translucent, whence the name "trans- parent pomade." IX. Castor oil av.oz. 17 Olive or cottonseed oil av.oz. 12 Spermaceti av.oz. 4 Oil of ylang ylang fl.dr. 5 Oil of rose drops 8 Oil of bergamot drops 8 Oil of neroli drops 5 Oil of rose geranium drops 2 Oil of bitter almond drop 1 Heliotropin gr. 1 Fuse the first three ingredients to- gether and add the perfume before it has congealed. The pomade appears to best advan- tage in transparent glass jars and in or- der that it may appear as coarsely crys- talline as possible, allow the congealing to go on as slowly as possible by placing the filled jars in warm water, and allow 082 THE STANDARD FORMULARY the mixture to stand undisturbed for 6 hours. X. Olive oil av.oz. 18 Spermaceti av.oz. 2 Oil of bergamot fl.dr. 2 Oil of clove drops 6 Oil of cinnaman drops 10 Oil of neroli drops 10 Dissolve the spermaceti in the oil by the aid of heat. Place the bottles up to the neck in water as hot as they will bear. Then fill with the pomade, adding the perfume immediately before pouring out. Cover the bottles as soon as they are filled, and do not disturb them until the pomade is perfectly solid. It may be colored with palm oil or oleaceous annatto coloring. The latter can be made by digesting 1 ounce of annatto in 8 ounces of olive oil. XI. Spermaceti av.oz. 1 Japanese wax av.oz. i*4 Castor oil . av.oz. 12^ Perfume, to suit. Tr is may be colored with alkannin. It is to be prepared like any of the pre- ceding. Marrow Hair Pomades. Under this heading are included a number of hair pomatums known by this name and which usually contain beef marrow. XIV. Beef marrow av.oz. 8 Beef suet av.oz. 4 Yellow wax av.oz. 1 Castor oil av.oz. 4 Oil of bergamot fl.dr. 2 Oil of lemon fl.dr. 1 Oil of orange fl.dr. 1 Melt the wax, suet and marrow, strain, allow to cool somewhat, and add the volatile oils. XV. Beef marrow av.oz. 4 Lard av.oz. 12 Melt together, strain, and perfume as desired. Anti-Kink Hair Pomade. XVI. Beef suet av.oz. 16 Yellow wax av.oz. 2 Castor oil av.oz. 2 Benzoic acid gr. 10 Oil of lemon fl.dr. 1 Oil of cassia drops 15 Mix the suet and wax, add the castor oil and acid, allow to cool somewhat, and incorporate the other oils. This is used for taking the kinks out of and straightening the hair. It is espe- cially adapted for use by colored people. Bear's Grease. A number of hair pomades are known by this title. It is almost needless to state that none of the preparations bear- ing this title are made with any ingredi- ents from the animal which furnishes the name. XVII. Beef marrow av.oz. 8 Lard av.oz. 24 Oil of lemon fl.dr. 6 Oil of rose drops 15 Oil of bergamot drops 15 Oil of cinnamon drop 1 Cumarin gr. 1 Mix the marrow and lard by fusion, strain, allow to cool somewhat, add the other ingredients and stir frequently un- til solid. BANDOLINE. This is a mucilaginous preparation applied by ladies to the hair before "frizzing" or curling, the object being to cause the hair to remain longer in curl. They may be either in powder or liquid form. Powders. I. Bandoline in powder form is us- ually powdered tragacanth perfumed by trituration with suitable aromatic vola- tile oils or synthetic perfume. In using, the powder is mixed with water to a suitably thick liquid, which is then ap- plied to the hair. II. This is a good formula: Tragacanth, powder av.oz. 2 Borax, powder gr. 30 Soap bark, powder gr. 20 Oil of rose geranium m. 30 Oil of rose drops 3 Oil of cinnamon drops 5 Oil of bitter almond drops 2 HAIR AND SCALP PREPARATIONS. 983 Mix well, first rubbing the oils with the borax. Use like the preceding. Liquids. These may be made with any kind of a mucilaginous substance such as traga- canth, quince seed, Irish moss, etc. If perfumed with rose, these may be known as "rose bandoline," if with benzalde- hyde or oil of bitter almond, "almond bandoline," etc. The toilet creams made with gum or mucilage may be used, or any of the following : III. Gum tragacanth, whole dr. 2 Water fl.oz. 12 Alcohol fl.oz. 2 Oil of rose drops 5 Add the gum tragacanth to the water, previously warmed. When the gum is thoroughly softened, strain the mixture with pressure through a cloth and add to it the oil of rose dissolved in the al- cohol. Any other essential oil or a syn- thetic perfume may be substituted for the rose oil. The preparation may be tinted pink or red by the addition of solution of carmine. If a thicker preparation is desired, more tragacanth may be added. IV. Tragacanth, powder av.oz. 1 Alcohol fl.oz. 2 Oil of neroli drops 15 Oil of rose drops 15 Water fl.oz. 24 Dissolve the oils in the alcohol and in a large mortar triturate the gum with this solution to a smooth mixture, and then incorporate with the water added all at once. The mixture may also be made by agitation in a bottle. V. Irish moss av.oz. 2 Water fl.oz. 16 Boracic acid dr. 2 Cologne water fl.oz. 2 Boil the Irish moss and boracic acid with the water, strain, add water to make 14 fluidounces, and mix with the cologne water. VI. Quince seed, bruised dr. 3 Water fl.oz. 14 Boric acid gr. 30 Cologne water fl.oz. 2 Macerate the seed in the water, pre- viously warmed, for 6 hours, agitating frequently, strain, in the liquid dissolve the boric acid by the aid of heat, allow to cool, and add the cologne water. HAIR-CURLING LIQUID. The first set of these preparations are of a mucilaginous character, the second are either alkaline or resinous. I. For keeping hair in curl: Borax powder av.oz. 1 Gum arabic gr. 30 Spirit of camphor fl.dr. 6 Water, warm fl.oz. 16 Dissolve solids in warm water, and when cool, add the camphor. Wet the hair with above and roll on papers as usual, let dry, unroll, and form into ringlets. II. Gum arabic av.oz. 1 Sugar av.oz. 1 Boric acid av.oz. Rose water fl.oz. 15 Mix and dissolve. Use like the preceding. III. For curling without papers : Sodium bicarbonate av.oz. Yz Borax av.oz. y 2 Cologne water fl.oz. 2 Alcohol fl.oz. 2 Tincture of cochineal fl.oz. 1 Water fl.oz. 24 Dissolve the two salts in the water, add the other ingredients, and strain or filter. IV. Tincture of benzoin fl.oz. i l / 2 Alcohol, to make fl.oz. 8 Perfume with oil of rose. DANDRUFF REMEDIES. Dandruff is known to medical men as seborrhea capitis, although other condi- tions produce similar results and are benefited by the same treatment, among these being dry eczema, psoriasis and pityriasis capitis. It is an inflammation of the sweat glands, characterized by 984 THE STANDARD FORMULARY rapid scaling of the upper layers of the skin. The scales or crusts are so abun- dant as to fill the hair as if with pow- der and also to cover the shoulders. Dandruff is always accompanied by more or less itching or irritation, which is more marked in summer time when the sweat glands are most active. On account of its infectious character, each person should have his own hair brush and comb, both at barber shop and at home, as one member of a family af- flicted with the affection may communi- cate it by means of these implements to all the other members of the family. Dandruff urgently requires 'treatment, as it will lead to great loss of hair and permanent baldness. Before beginning treatment for dand- ruff, it is necessary to thoroughly cleanse the scalp and hair, also all brushes and combs, with castile soap, green soap, liquid soap, shampoo, or other prepara- tion, to remove all the scales. Occa- sionally the washing may have to be re- peated, but too frequent washing of the head is injurious. The use of fine combs to scrape the scalp should not be coun- tenanced, as this irritates the skin and exposes it still more to the ravages of the disease. With the use of some dandruff remedies it is not necessary to wash the head frequently, as they com- bine detergent, or cleansing, and cura- tive properties. Favorite remedies for dandruff are resorcin and sulfur, the former being used in lotions, the latter in ointments or pomades. These have the added ad- vantage of being stimulants to the hair. Other common ingredients in dandruff remedies are chloral hydrate, salicylic acid, corrosive sublimate, tannin, and betanaphthol. These preparations may be perfumed to suit, and the lotions may be colored red, greenish, brown or yel- low as may be desired. Red color may be imparted with cudbear or carmine, green with chlorophyll, brown with madder or caramel, and yellow with turmeric or saffron. Lotions. I. Dr. H. L. Pearson highly recom- mends this treatment : Wash the head thoroughly with tere- bene soap (presumably other mild anti- septic soap would serve equally well), rinse well, and dry with a towel ; then rub in a lotion composed of Mercuric chlorid gr. 24 Glycerin fl.oz. 4 Cologne water fl.oz. 4 Water, to make fl.oz. 16 Dry the hair with a towel and apply a solution composed of Betanaphthol gr. 100 Alcohol fl.oz. 16 Allow this to evaporate spontaneously, and finally rub in a small quantity of an application consisting of Salicylic acid gr. 190 Comp. tincture of benzoin. fl. dr. 2J/2 Olive oil, to make fl.oz. 16 This treatment should be carried out daily for a month, then on alternate days for 2 weeks. The dandruff is said to disappear in a short time, the hair again becoming vigorous. II. Mercuric chlorid gr. 1 Resorcin dr. 4 Chloral hydrate dr. 8 Bay rum fl.oz. 8 Water, to make fl.oz. 14 If the hair is too dry, a small amount of castor oil, about 2 fluidrams, may be added to the above. This is to be rubbed into the scalp once a day. When dandruff ceases to form, use once every other day for two weeks, then once a week. III. Burnette's formula: Resorcin dr. 6 Salicylic acid gr. 20 Bay rum fl.oz. 16 Mix and dissolve the solids by agita- tion. The salicylic acid prevents the resor- cin from altering the color of the hair. This is to be well rubbed into the scalp 2 or 3 times a week. HAIR AND SCALP PREPARATIONS. 985 IV. Unna's Spiritus Capillorum : Resorcin gr. 160 Castor oil fl.dr. 2.y 2 Cologne water fl.oz. 3 Alcohol fl.oz. \2 l / 2 Apply once a day to the roots of the hair. All traces of soap and alkali must be removed from the hair before using this lotion to prevent discoloration. V. Gessner's Lotion: Resorcin dr. 3 Chloral hydrate dr. 4 Tannic acid dr. 4 Tincture of benzoin fl.dr. 1 Castor oil fl.dr. 4 Alcohol, to make fl.oz. 14 Apply once a day to the roots of the hair. The author of this preparation rather prefers the ointment mentioned below. VI. Foote's formula : Resorcin dr. 3 Glycerin fl.oz. 2 Alcohol fl.oz. 3 Rose water fl.oz. 6 Distilled water, to make. .. .fl.oz. 16 Use once a day. VII. An improved formula is the fol- ing: Wool-fat, anhydrous av.oz. 3 Quillaia av.oz. 1 Water, alcohol, each sufficient Macerate the quillaia in the water for several days, strain, filter the liquid, and add the alcohol. Then warm the liquid to above the melting point of the wool- fat and shake with the latter until well mixed. Finally add enough of a mix- ture of I part of alcohol and 6 of water to make 64 fluidounces. This is a milk-like liquid from which the wool-fat separates as a cream-like layer but which commingles readily with the liquid on agitation. Other substances such as quinine, tincture of cantharides, menthol, per- fume and other substances may be add- ed to this emulsion. Ointments. VIII. Dr. Jackson's Sulfur Cream : Precipitated sulfur dr. 6 Borax gr. 25 White wax dr. 6 Paraffin oil fl.oz. 4^ Rose water fl.oz. 2 Prepare like "cold cream," thoroughly incorporating the sulfur. This is to be applied once or twice a week. It is highly extolled by Dr. Jack- son. IX. j Dr. Gessner's ointment : Precipitated sulfur dr. 5 Resorcin dr. 2 Salicylic acid gr. 80 Tincture of benzoin fl.dr. 1^2 Petrolatum av.oz. 6 l / 2 Shampoo the head, dry thoroughly, then apply this ointment, rubbing well into the scalp. This treatment is to be continued every night. X. Shoemaker's remedy : Peru balsam dr. 2 Betanaphthol dr. 4 Benzoinated lard av.oz. 1 Wool-fat, hydrous av.oz. 3 Use like the preceding. XI. Salicylic acid gr. 140 Precipitated sulfur dr. 6 Cold cream, U. S. P av.oz. 7^ Cleanse the hair with a shampoo, then for 6 nights rub the above ointment thoroughly into the scalp and on the seventh night shampoo the head again. After six weeks of this treatment the dandruff will probably be cured, or at any rate the treatment may be contin- ued less frequently. XII. Bronson's ointment : Ammoniated mercury dr. Ij4 Calomel dr. -3 Petrolatum av.oz. 4' Shampoo the head with U. S. P. lini- ment of soft soap, rinsing thoroughly to remove all the soap, then rub in the above ointment every other night, alter- nating with a solution of 1 dram of resorcin in 8 ounces of diluted alcohol. Powders. XIII. Resorcin gr. 60 Boric acid gr. 30 Dissolve in 4 fluidounces of water be- fore use. 986 THE STANDARD FORMULARY XIV. Resorcin gr. 60 Tannof orm gr. 60 Salicylic acid gr. 5 Before use, dissolve in a mixture of 3 fluidounces of alcohol and I of water, and filter. FOR BALDNESS AND LOSS OF HAIR. Falling-out of hair, technically called alopecia, may be general (not confined to spots), due to various acute diseases such as typhoid fever, scarlet fever or erysipelas. It is frequently congenital (hereditary) and may be due to ad- vancing age; it may be due to physical weakness, nervous debility or severe mental application. It is frequently pro- duced by local causes such as dandruff, pityriasis, etc., also to pressure of tight- fitting hats which deprive the head and hair of proper nutrition. If the loss of hair is due to any local disease, this must be cured first when probably other treatment will not be required. By far the most prolific cause of baldness is dandruff. For dandruff remedies, see article immediately preceding this one. There is also a form of baldness known as alopecia areata which mani- fests itself in loss of hair in circular spots, usually being most severe in the central portion of the scalp. This dis- ease is believed also to be of contagious character. Various methods of treatment for alopecia or loss of hair have been of- fered and what are believed to be the best among these have been selected. Besides the remedies mentioned, see also those under the heading Hair Tonics. I. Lassar's routine treatment for the cure of baldness requires systematic at- tention for a period of at least 6 to 8 weeks. The head is lathered thoroughly with soap and hot water, preferably tar soap, rinsing well with warm water and then with cold water. This is to be done daily at first but less often after- wards. For washing long blonde hair, the following mixture is recommended: Potassium carbonate gr. 90 Sodium carbonate gr. 90 White castile soap, powder. av.oz. 1 Rose water fl.oz. 15 After thoroughly washing and drying the hair, moisten the roots of the hair with a mixture of Mercuric chlorid gr. 10 Cologne water fl.oz. 2 Glycerin fl.oz. 2 Rose water fl.oz. 12 Mercuric chlorid itself has the repu- tation of promoting the growth of hair. If there is itching, 15 minims of car- bolic acid may be added to this mix- ture. The following is then applied : Thymol gr. 10 Alcohol fl.oz. 8 Or this : Betanaphthol gr. 10 Absolute alcohol fl.oz. 8 After the hair has dried, this oint- ment is rubbed in the roots of the hair : Salicylic acid gr. 35 Tincture of benzoin gr. 70 Oil of bergamot drops 20 Petrolatum av.oz. 4 Formerly a neat's-foot oil mixture was advised, but pure neat's-foot oil is not always obtainable. Salicylic acid gr. 75 Tincture of benzoin fl.dr. 2 Neat's-foot oil fl.oz. 8 Every night the hair should be oiled with a mixture of turpentine and wool- fat containing 10% of the former, care being taken to avoid undue irritation of the skin, or with the following pomade: Carbolic acid gr. 45 Peru balsam gr. 90 Sulfur av.oz. 1 Oil o f bergamot m. 20 Wool-fat, anhydrous av.oz. 5 This is to be diluted with water be- fore use (amount not stated). II. A French writer, Dr. Sabourand, says the prime remedy to prevent loss of hair is to avoid greasy accumu- lation on the scalp by frequent washing with soap containing little or no potash, as this is irritating. The hair and scalp should be rinsed thoroughly with warm water, after which it should be dried with a towel, with the aid of heat if HAIR AND SCALP PREPARATIONS. 987 necessary. He advises against the use of cantharides, but thinks pilocarpine, quinine, caffeine and camphor stimulate the growth of hair. He suggests the following : Pilocarpine hydrochloric! ....gr. 6 Spirit of lavender fl.dr. 10 Ether . fl.dr. 10 Ammonia water fl.dr. 1 Alcohol, to make fl.oz. 16 Dissolve the alkaloid in a small amount of water and add the other in- gredients. This is to be rubbed into the scalp daily. III. Bartholow's prescription : Fluid extract of jaborandi. . .fl.oz. 2 Tincture of cantharides fl.oz. I Soap liniment r fl.oz. 5 Use once daily. IV. Recommended by Bulkley : Tincture of cantharides fl.oz. 1 Tincture of capsicum fl.oz. 1 Tincture of nux vomica fl.oz. 2 Castor oil fl.oz. 1 Alcohol or cologne water, to make fl.oz. 16 Apply once daily. V. Dr. McDonald's prescription: Resorcin dr. 6 Tincture of capsicum fl.oz. 2^2 Castor oil fl.oz. 1 Y / 2 Alcohol fl.oz. 12 Oil of rose, to perfume. Rub into the scalp once daily. VI. McKee's treatment : Tincture of jaborandi fl.oz. 1 Soap liniment fl.oz. 1 Cologne water fl.oz. 2 This should be rubbed into the scalp once daily. The jaborandi darkens the hair, hiding slight grayness. The same authority also recommends a mixture of Carbolic acid ."" fl.dr. 1 Salicylic acid dr. 3 Castor oil fl.dr. 3 Alcohol, to make fl.oz. 6 VII. Lactic acid has attained some reputation as a hair grower, according to some observers, growing hair even on nearly bald spots. A 25% solution in water is recommended. This is to be rubbed into the scalp until it causes pus- tulation. It is then to be discontinued until the pustules disappear, then to be used again. After the hair begins to grow, use the following mixture: Lactic acid . - fl.oz. 2 Quinine sulfate gr. 40 Glycerin fl.oz. 1 Water, to make fl.oz. 8 Apply daily to the hair as a dressing. It may be perfumed to suit with essen- tial oils or synthetics. The quinine and glycerin are said to prevent extreme ir- ritation. HAIR TONICS. The preparations known by the gen- eral title of hair tonics are intended as tonics to hair and scalp to prevent and cure dandruff, baldness, dryness of the hair, etc. The preparations under the preceding headings are also real hair tonics. Some of these preparations contain cinchona or quinine ; some contain sul- fur and lead salts ; others contain fixed oils like benne or cocoanut oil, and others contain still other ingredients. They are known by such titles as "hair restorer," "hair restorative," "hair invigorator," "hair vigor," "hair pro- moter," "hair grower," "hair lotion," "hair renewer," "hair wash," "hair reno- vator," "hair balsam," etc. The hair tonics of the market may be divided into three classes : 1. Mixtures of sulfur and glycerin, with or without lead acetate, depending on whether or not the preparation is to act as a dye as well as a tonic. The glycerin serves mainly to hold the sulfur in suspension, which latter is credited with hair-tonic properties and which in conjunction with the lead forms black lead sulfid on exposure to the air and light. (2) Di- lute alcoholic solutions, with or without glycerin or borax, containing" essential oils and some kind of hair stimulant, cantharides being the favorite, but cap- sicum also being employed. (3) A third class contains the constituents of cin- chona and sometimes of nux vomica. 9SS THE STANDARD FORMULARY Quinine and Cinchona Hair Tonics. (Eau de Quinine.) These preparations are usually dis- pensed under the titles "quinine hair wash," "quinine hair tonic," and "eau de quinine." They may be colored red, if desired, by means of red saunders or other red coloring. I. Quinine sulfate gr. 20 Bay rum fl.dr. 4 Glycerin fl.dr. 4 Tincture of cantharides. .. .fl.dr. 2 Tincture of capsicum fl.dr. 2 Water, to make fl.oz. 16 Mix, dissolve, and filter. II. Quinine sulfate gr. 20 Glycerin fl.oz. 1 Cologne water fl.oz. 2 Bay rum fl.oz. 2 Rose water fl.oz. 1 1 Mix, dissolve, and filter. III. Quinine sulfate Glycerin Tincture of cantharides, Rose extract Jamaica rum Alcohol Water Mix, dissolve, and filter. IV. ....dr. ..fl.oz. ..fl.dr. ..fl.dr. ..fl.oz. ..fl.oz. ..fl.oz. Quinine sulfate dr. 1 Fluid extract of jaborandi. .fl.oz. 1 Tincture of cantharides. .. .fl.oz. 1 Glycerin fl.oz. 2 Bay rum fl.oz. 12 Mix, dissolve, and filter. V. Quinine sulfate gr. 75 Tincture of cantharides. .. .fl.oz. 2 Weaker tincture of orris. . .fl.oz. 4 Cologne water fl.oz. 10 Water fl.oz. 10 Alcohol fl.oz. 8 Tincture of cudbear, enough to color. Dissolve the quinine in the cologne water and alcohol, add the tinctures, coloring and water, let stand a few hours, and then filter clear. Enough coloring should be added to give a bright red color. More perfume may be added to suit. VI. Tincture of red cinchona. . .fl.oz. 1 Tincture of cantharides. .. .fl.dr. 2 Comp. tincture of lavender. fl.dr. 2 Glycerin fl.oz. 2 Alcohol, to make fl.oz. 16 Hair Tonics Containing Oil. VII. Castor oil fl.oz. 10 Alcohol fl.oz. 20 Tincture of cantharides fl.dr. 4 Oil of bergamot fl.dr. 4 Oil of rose drops 10 Red saunders dr. 2 Mix, macerate for several days, agi- tating occasionally and strain. VIII. Castor oil fl.oz. 8 Tincture of cantharides fl.oz. 1 Tannin dr. 1 Oil of bergamot fl.dr. 1 Oil of clove fl.dr. 1 Oil of lavender flowers drops 20 Oil of rosemary drops 20 Alcohol .* fl.oz. 23 Oil and Quinine Hair Tonic. IX. Quinine sulfate gr. 75 Castor oil fl.oz. 2 Tincture of cantharides fl.oz. 2 Oil of bay m. 30 Alcohol fl.oz. 28 Tincture of curcuma, to color yellow. Mix, agitate till the quinine is dis- solved, and filter. Hair Tonics Containing Resorcin. X. Resorcin dr. 2 Salicylic acid gr. 20 Tincture of cantharides. .. .fl.dr. 4 Glycerin fl.oz. 1 Diluted alcohol, to make.', .fl.oz. 16 Heliotropin gr. 10 Oil of rose drops 5 XI. Resorcin gr. 90 Glycerin fl.dr. 4 Tincture of cantharides fl.dr. 4 Compound tincture of lav- ender fl.dr. 4 Bay rum, to make fl.oz. 16 XII. Resorcin dr. 2^/2 Tannin dr. 5 Chloral hydrate dr. 5 Castor oil fl.oz. 2 Tincture of benzoin fl.oz. 2 Vanillin gr. 20 Alcohol, to make fl.oz. 32 HAIR AND SCALP PREPARATIONS. 989 Lanolin Hair Lotion. XIII. See Liebreich's Hair Milk, un- der Dandruff Remedies. Pilocarpine Hair Tonics. Pilocarpine is used frequently as an ingredient of hair tonics. It was first used as tincture of fluid extract of jab- orandi in connection with quinine, as in formula No. IV under Quinine and Cin- chona Hair Tonics, which see. Pilocarpine is reputed to possess the property of darkening the hair as well as promoting its growth. A pomade as well as lotions is mentioned here. XIV. Jaborandi av.oz. x / 2 Cinchona av.oz. I Glycerin fl.oz. 2 Diluted alcohol, to make. . .fl.oz. 16 Perfume, to suit. Reduce the drugs to coarse powder and percolate with the diluted alcohol to obtain 14 fluidounces of liquid; to the latter add the glycerin and any suitable perfume. XV Quinine sulfate pt. 20 Tincture of jaborandi fl.oz. 1 Glycerin fl.oz. 1 Cologne water fl.oz. 2 Bay rum fl.oz. 2 Rose water fl.oz. 11 Diluted sulfuric acid m. 20 Dissolve the quinine in the rose water with the aid of the acid, a old the other ingredients, and filter. Sage Hair Tonic. XVI. Utech's formula : Fluid extract of sage fl.oz. 2 Tincture of green soap. .. .fl.oz. 2 Tincture of red cinchona. . .fl. dr. 6 Tincture of cantharides. . . .fl.dr. 3 Glycerin fl.oz. 1 Chloral hydrate dr. 5 Cologne water fl.oz. 4 Oil of bergamot fl.dr. 1 Oil of sweet orange fl.dr. 1 Oil of neroli drops 10 Alcohol fl.oz. 1 California brandy, to make. fl.oz. 32 Mix the first five ingredients together, dissolve the chloral hydrate in the co- logne water, dissolve the oils in the al- cohol, add this to the cologne water so- lution and mix all the ingredients to- gether. Let stand for a week or longer, and then filter through calcium phos- phate. Arnicated Glycerole of Cantharides. XVII. Ammonium carbonate dr. 1 Ammonium chlorid dr. 1. Salicylic acid gr. 20 Glycerin fl.oz. 1 Cologne water fl.oz. 1 Tincture of arnica fl.oz. 2 Tincture of cantharides. .. .fl.oz. 2 Alcohol '. fl.oz. 2 Water fl.oz. 8 Dissolve the ammonium salts and sali- cylic acid in the water, add the other in- gredients and filter clear through cal- cium phosphate. This mixture shampoos or cleanses the head as well as stimulating the growth of the hair. It is to be applied night and morning, rubbing well into the roots of the hair. Prof. Gross's Hair Tonic. XVIII. Tincture of cantharides. .. .fl.dr. 4 Tincture of capsicum drops 50 Glycerin fl.dr. 10 Cologne water, to make fl.oz. 16 Locock's Hair Lotion. XIX. There are many variations of this formula, but the following is said to be the original : Expressed oil of mace gr. 1 10 Olive oil fl.oz. 1 Stronger ammonia water, .fl.oz. 1 Spirit of rosemary fl.oz. 2 Rose water, to make fl.oz. 20 Beat up the oil of mace with the olive oil, added, not too gradually; after each addition and incorporation of olive oil add a small amount of the ammonia water, beating until the mixture is sap- onified. When all the olive oil has been added, incorporate the rose water, then the spirit of rosemary, and finally the remainder of the ammonia water. Erasmus Wilson's Hair Lotion. XX. This is said to be the original formula for this preparation as given bv Dr. Wilson himself: 990 THE STANDARD FORMULARY Sweet almond oil fl.oz. 2 Stronger ammonia water. . .fl.oz. 2 Chloroform m. 50 Oil of rosemary m. 90 Oil of lemon drops 2 Alcohol, to make fl.oz. 16 Father Kneipp's Hair Tonic. XXI. There may be occasional calls for this preparation. This is the for- mula: Boil 200 g. of finely cut fresh nettle root in 1000 cc. of water and 500 cc. of vinegar for one-half hour, allow to cool and then strain. The scalp is to be washed thoroughly with this lotion every evening before retiring. Lead and Sulfur Hair-Color Restorers. These are the preparations that have been sold in the past under .such names as "hair promoters," "hair vigors," "hair invigorators," "hair restorers (or restor- atives)," etc. The sulfur and lead are not only alleged to be hair tonics, but act also as slow dyes or coloring agents, darkening grayish hair, and in this man- ner restoring its color. The sulfur and lead combine upon exposure to air and light to form black lead sulfid. On account of the action of light, these preparations should al- ways be either in dark amber-colored bottles or the container should be cov- ered with a closely-adherent wrapper. Lead preparations being all poisonous, it would seem that the public should be apprised of this fact. However, cases of poisoning from the use of these hair preparations are seemingly un- known. The lead in these preparations is usu- ally in the form of the acetate but the nitrate is equally serviceable. The sul- fur is employed in the form of precipi- tated or sublimed (or better, washed), sulfur. It may also be in combination with sodium hyposulfite. When this lat- ter is added to the lead salt, a precipi- tate of lead hyposulnte is formed which must be redissolved in an excess of the hyposulfite. The hyposulnte prep- arations are therefore clear while the sulfur preparations contain sulfur in suspension and must be agitated befor? use. Other ingredients of these prepara- tions are glycerin, which helps to keep the sulfur in suspension, tincture of cantharides, perfume, alcohol, water, bay rum, rose water, etc. These preparations should be applied once or twice daily to the hair. XXII. Formula of the British Pharmaceutical Codex: Lead acetate, powder av.oz. 34 Precipitated sulfur av.oz. iV 2 Glycerin fl.oz. 5 Distilled water, to make fl.oz. 40 Rub the lead salt and sulfur together until well mixed, triturate with the gly- cerin, and gradually add enough dis- tilled water to make up the required vol- ume. This may be perfumed if desired. XXIII. What appears to be the orig- inal, or at least one of the early prepa- rations of this kind is the following, known as Gen. Twigg's Hair Restorer or Dye: Precipitated sulfur dr. 4 Lead acetate dr. 4 Rose water fl.oz. 16 Triturate all together in a mortar. The addition of 2 fluidounces of gly- 'cerin will remove the undersirable dry- ing property of the preparation. XXIV. Lead acetate, pure av.oz. 1 Ammonium hyposulfite, crystal av.oz. 2 Alcohol fl.oz. 1 Glycerin fl.oz. 1 Oil of bitter almond drops 20 Distilled water, to make fl.oz. 64 Dissolve the salts separately in a por- tion of the water and mix the solutions. Dissolve the oil in the alcohol, add the glycerin, and mix this with the previ- ously prepared compound. Other per- fume may be added and the amounts of alcohol and glycerin may be some- what increased. XXV. A pomade for the hair also containing lead and sulfur is this: 1 HAIR AND SCALP PREPARATIONS. 991 Lead acetate, fine powder, .av.oz. T /i Precipitated sulfur av.oz. Yi Tincture of cantharides. .. .av.oz. I Oil of rosemary fl.dr. I Oil of lavender flowers fl.dr. I Wool-fat, hydrous av.oz. 4 Castor oil fl.oz. 5 Petrolatum av.oz. 6 Rub the lead acetate and sulfur to a smooth oaste with a portion of the cas- tor oil, add the petrolatum, wool- fat, and remainder of the castor oil, and then incorporate the tincture and es- sential oils. This is to be applied once daily. LIME JUICE AND GLYCERIN. This preparation was at one time a popular one for the hair. Very singu- larly it does not contain lime juice and seldom glycerin, but is made with a basis of lime water and oils, with oil of lemon as the perfume. The following formulas are offered: I. Sweet almond oil fl.oz. 7 Oil of lemon fl.dr. 2 Lime water, to make fl.oz. 16 Mix well by shaking. II. Sweet almond oil fl.oz. 6 Olive oil fl.oz. 6 Lime water .fl.oz. 5 Syrup of lime fl.oz. 1 Oil of lemon fl.dr. 1 Mix well by agitation. Peanut oil may be used instead of the almond and olive oils. All fixed oils do not make . a smooth mixture with lime water. OINTMENT FOR DRY SCALP AND HAIR. Wool fat, hydrous av.oz. 4 White petrolatum av.oz. 4 Oil of lavender -flowers. .. .drops 20 Apply to the scalp with the tips of the fingers about twice a week. HAIR GLOSS. Hair glosses are for the purpose of giving a gloss and a smooth, soft ap- pearance to the hair, glycerin or castor oil being the main ingredient which is dissolved in alcohol and perfumed with essential oils or synthetic perfumes to suit the taste and price. Besides the preparations mention below, the mix- tures known as brilliantines, which see, are also used as hair glosses. I. Castor oil fl.oz. 4 Alcohol, fl.oz. 12 Oil of lavender flowers m. 30 . Oil of bergamot m. 30 Color with alkanet if desired. II. Glycerin fl.oz. 2 Alcohol fl.oz. 2 Orange flower water fl.oz. 2 Rose water fl.oz. 10 Oil of verbena m. 30 Oil of rose geranium m. 30 Oil of citronella (best) m. 30 HAIR DYES. (Mustache Dyes- Whisker Dyes.) It is a common practice to dye faded or gray hair, or to, using a more polite expression, "restore" them, by the use of various liquid preparations. These may be made with mineral agents as the base but vegetable substances are used also and latterly synthetic agents have come into vogue. Among the metallic substances used are silver, lead, bismuth, copner, nickel, mercury, etc., are used, any in fact which will form a black or brown com- pound in contact with a reagent. Sil- ver is the most popular because it is most effective and most expeditious. Some of the metals are interdicted in. Europe as being poisonous or deleterious, including copper, lead, mercury, nickel, and in some instances silver. Bismuth preparations are, however, entirely non- poisonous and may be used freely. The vegetable dyes include walnut shells, henna leaves, and cashew nuts, but they are rather unsatisfactory as compared with the metallic dves. All metallic d-es require the use of a second or mordanting agent to "fix" the color such as pyrogallic acid or a sulfite with silver, etc. Sometimes it is possible to combine the dye and mor- dant in one solution which then makes a so-called one-bottle preparation where- 992 THE STANDARD FORMULARY as when the dye and mordant are sep- arate, a two-bottle preparation is ob- tained. All dyes must be renewed from time to time as the new portions of the hair of course, still retain the former color. The usual color desired is black, al- though brown is also largely in de- mand. The dyes that produce a black color will produce a brown by appropri- ate weakening or dilution. Before using any dye, the hair should be freed from grease by washing with an alkaline carbonate or soap, removing the latter by the abundant use of water, subsequently drying thoroughly. The dye should be distributed among the hair by means of a tooth brush and occasional combing with a new comb ; contact with the scalp should be avoided. Silver Hair Dyes. Silver dyes may be the so-called one- bottle or two-bottle preparations, the latter consisting of a bottle of mor- dant (pyrogallic or gallic acid or other agent) and a bottle of silver solution. The mordant is always applied to the hair first. In the case of one-bottle prep- arations, the single bottle is a solu- tion of the silver salt. The mordanting or darkening effect is obtained by ex- posure of the hair to the sun. One bot- tle preparations do not make so good a color as the two-bottle ones. I. Black or brown — 2-bottle : A. Silver nitrate dr. 4 Ammonia water sufficient Distilled water, to make fl.oz. 4 Dissolve the silver nitrate in a por- tion of the water, gradually add am- monia water, stirring constantly, until the brown turbidity produced has van- ished and the liquid appears colorless, then add the remainder of the water. A large excess of ammonia should be avoided as this tends to produce a brownish dye. B. Pvrogallic acid dr. 1 Alcohol fl.dr. 4 Distilled water, to make. .. .fl.oz. 4 Mix and dissolve. Before using this dye the hair should be freed from grease by washing with warm water containing sodium or po- tassium carbonate, borax or soap, then well rinsed with clear water to remove all alkali, and finally dried thoroughly. In using, apply solution B to the hair w T ith a clean tooth brush, going care- fully over every portion of the hair, allow the latter to dry partially, then apply solution A in the same manner, using another clean tooth brush. The above makes a black dye. To ob- tain a brown dye the solution of pyro- gallic acid should be made very weak, about 20 grains to 4 ounces, and the solution of silver nitrate should also be reduced to one-half or one-quarter. In fact, any shade of color may be ob- tained by altering the strength of the solutions. Care should be taken to avoid stain- ing the scalo. If a stain is made, it may be removed with solution of sodium hyposulfite. II. Black or brown — 2-bottle : Silver nitrate dr. 4 Ammonia water sufficient Distilled water, to make fl.oz. 4 Dissolve the silver salt in a portion of the water, add ammonia water, in small amounts, with repeated agitation, to just redissolve the precipitate first formed, then add the remainder of the water. B. Gallic acid gr. 40 Water fl.oz. 3 Alcohol fl.oz. 1 Mix and dissolve. This is to be used like the preced- ing. These combinations make a black dye. Brown or light may be obtained by us- ing an excess of ammonia in solution A - HAIR AND SCALP PREPARATIONS. 993 or by diluting or weakening the solu- tions. Use like No. I. III. Black or brown — 2-bottle: A. Silver nitrate dr. 4 Copper nitrate gr. 24 Ammonia water sufficient Distilled water fl.oz. 4 Dissolve the two salts in the water, add ammonia water to redissolve the precioitate first formed. B. Pyrogallic acid dr. 2 Acetic acid fl.dr. 6 Alcohol fl.oz. 4 l / 2 Apply the pyrogallic solution to the hair with a tooth brush, taking care not to wet the scalp. When partially dry, apply the silver solution in the same manner, using another brush. This makes a black dye. For a brown dye, decrease the amount of pyrogallic acid; as little as one-half grain to the fluidram is sometimes used. Sometimes the acetic acid is omitted, and in most of the commercial hair dyes diluted al- cohol is used as a solvent of the acid. Copper sulfate might possibly be sub- stituted for the nitrate. The use of the copper salt is to avoid the dull reddish tint imparted to hair by the use of silver nitrate alone. IV. Black— 1 -bottle: Silver nitrate dr. 2 Ammonia water fl.oz. 1 Lard oil fl.dr. 4 Distilled water, to make fl.oz. 8 Saponify the oil by shaking it with the ammonia water; dissolve the silver nitrate in the water, and add this to the oil solution. Let the mixture stand for some time with frequent agitation. This liquid is to be applied to the hair by means of a tooth brush, being care- ful to apply it to all the hair and up to the roots, then loosen up or shake out the hair and expose to the sun which brings out the color. Age seems to im- prove the dyeing property of this prep- aration. Bismuth Hair Dyes. While hair dyes made with silver, copper, lead, mercury, nickel, etc., are considered poisonous and some are for- bidden in European countries, bismuth dyes are known to be entirely harmless. The objection to them is that they do not operate so quickly and that the solu- tions decompose on exposure to light and air. They are also quite expensive. They should therefore be kept in dark bottles, well stoppered. They are pre- ferred to make the light brown or so- called chestnut color. V. Brown or blonde — i-bottle: Bismuth subnitrate gr. 125 Solution of potassa, 10%. Citric acid, each sufficient Glycerin fl.oz. 3 Distilled or orange flower water, to make fl.oz. 8 Mix the bismuth salt and glycerin intimately by trituration, then heat on a water-bath and gradually add to it solution of potassa, under constant stir- ring, until the bismuth salt is dissolved. Then add concentrated solution of citric acid until only a slight alkanity remains. Now add water to make up the 8 fluidounces. This is to be applied by means of a new tooth brush and comb. Copper Hair Dyes. Copper dyes are considered poison- ous and in Germany and other Euro- pean countries are forbidden for use on living hair. They may be used on wigs, switches, etc. VI. Black— 2-bottle : A. Copper sulfate gr. 80 Ammonia water m. 200 Distilled water fl.oz. -] x / 2 B. Pyrogallic acid gr. 35 Copper acetate gr. 175 Distilled water fl.oz. y l 2 Apply like any of the silver dyes. VII. Black— 2-bottle : A. Copper sulfate dr. 2 Copper acetate dr. 2 994 THE STANDARD FORMULARY Pyrogallic acid gr. 24 Distilled water fl.oz. g l / 2 Ammonia water fl.dr. 4 B. Potassium ferrocyanid. . . .av.oz. 1 Distilled water fl.oz. 10 Apply solution A thoroughly with a brush, allow the hair to dry spontane- ously, then apply solution B in the same manner. VIII. Brown— 2-bottle : A. Copper chlorid gr. 80 Distilled water fl.oz. 4 B. Pvrogallic acid dr. 2 Alcohol fl.oz. 3 l / 2 Distilled water fl.oz. 4 l / 2 Apply like any of the silver dyes. This makes a dark brown shade. A light brown shade may be made by de- creasing the proportion of copper chlorid to 50 grains and that of pyro- gallic acid to 80 grains. Iron Hair Dyes. Iron being entirely non-poisonous has been suggested as a basis for hair dyes instead of silver, lead, copper, or mer- cury. Iron dyes are, however, not as satisfactory as those containing silver or bismuth. Examples of iron dyes are here given. IX. Black— 2-bottle : A. Iron sulfate gr. 5 Glycerin fl.dr. 4 Distilled water, to make fl.oz. 8 B. Tannic acid gr. 20 Gallic acid gr. 20 Distilled water, to make fl.oz. 8 The hair must be thoroughly washed with solution A, dried and brushed, once daily for three days; then solution B should be applied on a small-toothed comb, but must not be allowed to touch the skin if A has done so, else a tem- porary stain will result. Subsequently both liquids may be used once daily, at an interval of an hour or so, until a black color is produced. X. Black— 1 -bottle: Iron sulfate dr. 2 Glycerin fl.oz. "1 Cologne water fl.oz. 1 Rose water fl.oz. 14 This is to be applied to the hair once or twice daily. It gradually darkens the hair. Mercurial Hair Dye. Owing to the poisonous character of mercury, this is to be used only on wigs, switches, etc., not on living hair. XI. Black— 2-bottle : A. Mercuric chlorid gr. 6 Ammonium chlorid gr. 6 Distilled water fl.oz. 3 B. Sodium hyposulfate gr. 10 Water fl.oz. 2 The hair should be washed to free it from grease, then treated with solution A, allowed to dry. and then treated with solution B. Lead Hair Dyes. The lead dyes are considered poison- ous and are usually not recommended. In fact some European countries have laws forbidding their use on human beings. For formulas for these prepa- rations, see Lead and Sulfur Hair-Color Restorers under Hair Tonics. Manganese Hair Dyes. XII. Blonde— 2-bottle : A. Potassium permanganate gr. 80 Distilled water fl.oz. 4 B. Sodium hyposulfite gr. 80 Distilled water fl.oz. 4 Free the hair from grease by wash- ing with a weak soda solution, then rinse thoroughly with warm water, and dry well with a soft towel. Then apply solution A, with a soft, clean tooth brush, afterwards combing with a clean comb to evenly distribute the solu- tion. After a short time, sponge the hair with clean water, then brush them with solution B until the manganese color is discharged. HAIR AND SCALP PREPARATIONS. 995 Solution A is also used alone, the depth of color obtained varying with the frequency with which it is ap- plied. Pyrogallol Hair Dye. Pyrogallic acid (pyrogallol) is also used without metallic combination to dye the hair. The following are some of the formulas recommended: XIII. Pyrogallic acid oz. I Alcohol fl.oz. 2 Water fl.oz. 6 This imparts to the hair a dark brown color. It is to be applied to thejiair once daily until the desired shade is obtained. XIV. Pyrogallic acid dr. 4 Solution of potassa dr. 4 Water, to make... fl.oz. 6 This makes a brown color. It is to be used like the preceding. Walnut Hair Oil and Dye. Oils impregnated with the coloring principles of walnut shells have been recommended for dyeing the hair, thus serving as a combined oil and dye. The oil is to be applied daily, the hair ac- quiring a dark brown tint. The follow- ing are the best formulas : XV. Paraffin oil fl.oz. 16 Alum, powder dr. 4 Walnut shells, dried av.oz. 4 Alcohol sufficient Perfume to suit Moisten the shells with alcohol, add the alum and paraffin oil, heat on a sand bath for an hour, then filter, and finally add any desired essential oils or synthetic perfumes. XVI. Walnut shells, green or fresh av.oz. 3 Alum, powder dr. 3 Olive oil fl.oz. 16 Oil of rose drops 15 Oil of bergamot drops 25 Beat the walnut shells in a mortar with the alum, then heat with the olive oil until all moisture has dissipated, 63 filter, allow to cool, and add the aro- matic oils. XVII. Many of the so-called "wal- nut dyes" are not made from walnut shells at all, but are chemical origin, the following being given as an example : Silver nitrate gr. 45 Pyrogallic acid dr: 3 Distilled water fl.oz. 2 Glycerin fl.oz. 6 Henna Hair Dye. The leaves of the henna, a Southern Asiatic plant, have long been used by Oriental women as a dye for the hair and finger nails. One method of using the leaves is to make a decoction with boiling water in about the proportion of 1 in 7, and to apply this uniformly to the hair, after first washing the latter to remove all grease. Owing to the gummy character of the leaves, the hair becomes disagreeably sticky after mak- ing the application. The decoction spoils readily but may be preserved for some time by adding about 20% of alcohol, which also precipitates a portion of the gum. The leaves may also be extracted with diluted alcohol, and this tincture is also suitable as a dye. This dye is entirely harmless and may be used in any amount, but must not be used so freely as to stain the skin. It imparts to the hair a dark brown or black color which is quite lasting. It is also used in the form of a pow- der which is mixed with water and applied "to the hair in the form of a paste. This is allowed to remain over night, and is washed off the next day with water. Oriental women are said to use henna leaves in connection with the leaves of the indigo plant, known as "reng." The color may be varied by using differ- ent proportions of reng and henna, the more of the former that is used, the darker will be the shade produced. Synthetic Hair Dyes. A number of substances or combina tions of substances, of synthetic origin. 996 THE STANDARD FORMULARY most of them similar to photographic developers, have been recommended of late years for dyeing hair. As a rule most of them are irritant to the skin and produce eczemas and other cutane- ous eruptions. They are therefor suit- able only for dyeing furs, wigs, switches, etc. One of the chemicals most frequently mentioned in this con- nection is paraphenylenediamine. Ac- cording to the specifications of a Ger- man patent it is to be used as fol- lows : A. Paraphenylenediamine . .parts 20 Caustic soda -parts 14 Water parts 1000 B. Hydrogen dioxid parts 3 Water parts 100 Cleanse the hair thoroughly so as to remove all fatty matter, then apply solu- tion A, allow the hair to dry partially, and then apply solution B. In the course of the day the hair assumes a dark color, which becomes deeper upon repeated applications of the dye. The preparation known as Aureol, also protected by a German patent, con- sists of Metol parts 10 Amidophenol hydro- chlorid parts 3 Monamidophenylamine ..parts 6 Sodium sulfite parts 5 Diluted alcohol, to make. parts 1000 Dissolve the sulfite in the alcohol and all the other ingredients. • In using this dye the hair should first be washed with soda solution or soap, rinse thoroughly with clear water, allowed to dry partially, then with a fine-tooth comb apply this liquid pre- viously mixed with an equal propor- tion of a 3% solution of hydrogen per- oxid. In the course of 2 or 3 hours the hair will assume a dark-brown color which can be increased to black by re- peated applications of the dye. A German patent has also been is- sued for a hair dye which is said to be "relatively" non-poisonous and which does not irritate the skin. The hair is first treated with a dilute alcoholic, slightly alkaline solution of naphthy- lendiamine, and then washed with an oxidizing solution. The result is a blonde or light brown tint, which re- sists the influence of light, or water and of the substances ordinarily used in washing the hair. Golden Hair Coloring. To bleach the hair, hydrogen peroxid only is used at the present time. Be- fore using it the hair should be freed from grease and dirt by washing thor- oughly with soap and water containing a small amount of ammonia water. Dry the hair partially, then apply the peroxid by means of a sponge or in any other convenient manner. Comb the hair out so as to distribute the bleach evenly through the hair and to expose the latter quite thoroughly to the air. If the shade obtained is not light enough, repeat once daily for several days till the desired tint is obtained. The color obtained depends not only upon the frequency with which the bleach is used but also upon the con- stitution of the hair, to which also the natural color of the hair is due. Red hair is but little affected by the bleach because of the small proportion of iron present ; black hair is affected the most. Hair Dye in Ointment Form. According to Gawaloski, an effective hair dye may be made by washing fresh- ly precipitated silver oxid with alcohol, and making this into an ointment with any suitable vehicle. This ointment is to be rubbed into the hair at night, and in the morning washed out with a weak alcoholic solution of pyrogallic acid and potassa. After a few minutes exposure to the light, wash the hair with water, and apply a little oil. BRILLIANTINES. These are preparations intended for application to the mustache, beard or to make them appear glossy. They are therefore similar to the preparations HAIR AND SCALP PREPARATIONS. 997 called Hair Glosses, which see. They consist of a mixture of alcohol, fixed oils or glycerin (or both together), and some perfuming agent. There are two varieties, the separating and the non- separating, the former separating on standing into two layers. The cause of the separation is the presence of fixed oil other than castor oil which is not soluble in alcohol or alcoholic liquids; the presence of glycerin and possibly of water also contribute to the. separa- tion. The non-separating kind consists of castor oil or glycerin in alcoholic solution. The perfume is an important con- sideration. It may be any suitable com- bination of essential oils or synthetic perfumes. The formulas under Per- fumes for Hair Oils are excellent for this purpose. Or instead of alcohol and tssential oils in the mixture, a good handkerchief extract may be used. Too much perfume in the mixture is unde- sirable. If a colored preparation is desired, it may be tinted yellow with tincture of saffron or curcuma or reddish with al- kanet root of alkannin. I. Castor oil fl.oz. I Sweet almond oil fl.oz. 7 Glycerin fl.dr. 3 Jockey club extract fl.dr. 6 Alcohol, to make fl.oz. 16 II. Sweet almond oil fl.oz. 9 Alcohol fl.oz. 5 Glycerin"' fl.oz. 2 Oil of rose geranium drops 15 III. Castor oil fl.oz. 6 Alcohol fl.oz. 10 Oil of rose drops 20 Oil of neroli drops 20 Mix, and color with tincture of saf- fron or curcuma. IV. This preparation is more like a pomatum : Castor oil av.oz. 15 Spermaceti av.oz. 4 Oil of bergamot fl.dr. 2 Palmarosa oil fl.dr. 1 Geranyl acetate m. 30 Melt the spermaceti, add the castor oil, allow to cool somewhat, and then incorporate the perfume. V. The "huiles antiques" imported from France may be made into fine brilliantines by mixing them with an equal proportion of alcohol. STICK MUSTACHE POMADE. (Stick Pomatum — Cosmetique.) For a formula suitable as a basis for these preparations see under Grease Paints. The fatty combination men- tioned when uncolored forms white cosmetic, when colored with burnt um- ber, brown cosmetics, and when colored with lampblack or animal charcoal, black cosmetic. The coloring matter should be rubbed to a perfectly smooth paste before adding to the remainder of the fatty matter. The mixture may be colored mildly with any suitable essen- tial oil or synthetic perfume, or with any of the combinations mentioned un- der Perfumes for Hair Oils. After the mixture has been melted and colored and perfumed if desired- it should be allowed to cool to near the congealing point, and then poured into well-chilled molds of the proper di- mensions. After the sticks have solidi- fied, they should be removed from the molds, and wrapped in oiled paper or tin-foil, after which they may be en- closed in a fancy wrapper. Instead of a portion of the fatty mat- ter and then adding perfume, flower pomades may be used as in the fol- lowing: White wax av.oz. 8 Suet av.oz. 8 Tuberose pomade av.oz. 4 Jasmine pomade av.oz. 4 First melt the wax, then add the suet, afterward the pomades. The following is also recommended as a basis for mustache pomades : Spermaceti av.oz. 1 White or yellow wax av.oz. 7 Olive oil tl. or av.oz. 9 Melt the wax and spermaceti and add 998 THE STANDARD FORMULARY the oil. The coloring matter and per- fume may be added as before. For the white pomade use white wax, but for colored pomades yellow wax may be used. HUNGARIAN MUSTACHE PO- MADE. (Hungarian Mustache Wax — Pommade Hongroise.) This is a mixture of gum, soap, wax or spermaceti, and water, with perfume and coloring matter. It is in the form of a sticky or tenacious paste which, when applied to the end of the mus- tache, retains the latter in extended fashion, a la Napoleon III. It may be left uncolored, or it may be colored brown with umber or black with lampblack like stick mustache, the coloring matter being first rubbed up with a portion of melted wax or the glycerin or water before adding to the other ingredients. Owing to the fact that it will become, hard and dry when exposed to the at- mosphere, it must be preserved and dis- pensed in well-stoppered wide-mouth bottles or in collapsible tubes. I. Spermaceti dr. 2 White or yellow wax av.oz. 2.^/2 Acacia, powder av.oz. 2 White castile soap, powder. av.oz. i l /+ Glycerin fl.dr. 2 Water fl.oz. 6 Oil of bergamot m. 30 Oil of rose geranium m. 30 Rub the soap and gum with half the water, previously warmed, to a per- fectly smooth paste. Melt the wax and spermaceti, add the remainder of the water, then incorporate the soap and gum mixture, and the glycerin, adding these gradually with constant stirring. Then allow the whole to cool partially before adding the oils. White wax is to be used for white or light-colored pomade, while yellow wax may be used for dark pomade. II. White castile soap, powder. av.oz. 2 White wax av.oz. 5 Mucilage of acacia fl.oz. 6 Water ." fl.oz. 5 Glycerin fl.oz. 1 Yz Oil of bergamot drops 12 Oil of lemon drops 6 Oil of rose drops 6 Triturate the soa^ with the mucilage previously mixed with the water to a smooth paste. To this add the wax and glycerin, heat the whole on a water bath, stirring constantly, until the wax is melted, and the mixture is homo- geneous. Now, incorporate the volatile oils, also coloring matter, if a colored pomade is desired. III. This is a Hungarian formula : White wax av.oz. 9J/2 Lard av.oz. 2>Va Venice turpentine av.oz. 3^ Gum elemi av.oz. 1 Melt together at a gentle heat and stir until cool. MUSTACHE VARNISH. The following is recommended for imparting stiffness to the mustache and beard: Mastic dr. 2 Sandarac dr. 4 Resin av.oz. iyk Alcohol fl.oz. 4 Ether fl.dr. 4 Any perfume extract. fl.dr. 4 Mix and agitate until the resins are practically dissolved, then strain. Some castor oil may be added. SPIRIT GUM for Attaching False Beards and Mustaches. This is generally a resinous prepara- tion such as an alcoholic solution of mastic or an ethereal solution of san- darac. Or the following may be used: I. Mastic dr. 1 Sandarac dr. 2 Rosin dr. 6 Ether fl.dr. 2 Alcohol fl.oz. 2 Mix and dissolve by agitation. II. Rosin dr. 4 Castor oil fl.dr. 2 Alcohol fl.dr. 10 Volatile oil to perfume Mix and dissolve by agitation. HAIR AND SCALP PREPARATIONS. 999 EYE-BROW PENCILS. For full directions for making eye- brow pencils, see under Grease Paints in Chapter II. SHAVING PREPARATIONS. Two kinds are described here, shav- ing creams and shaving powders. The manufacture of soaps requires special ability and experience and will not be discussed. Creams or Pastes. These are merely soft soaps and also require the special ability of a soap- maker to prepare them. The follow- ing formulas are well recommended: I. Modified from Piesse: Lard av.oz. 14 Caustic potassa av.oz. 2 Water fl.oz. 6 Perfume to suit Melt the lard in a porcelain vessel over a salt water bath; dissolve the potassa in the water, and run the lye, thus formed, very slowly into the melted grease, stirring thoroughly all the time, until saponification is complete. A pearly appearance can be given to the "cream," which is simply a soft soap, by long trituration in a mortar with a little alcohol, say 4 fluidrams to each pound of soap. Bitter almond oil may be used as a perfume for the "cream." Only a very minute proportion is required. A few drops dissolved in the alcohol used as above will suffice. Glycerin should be added to this cream to retain it in a permanently soft condition. II. From Dieterich : Mutton tallow av.oz. 8 Cocoanut oil av.oz. 4 Solution of soda, sp. gr. 1.26 av.oz. 6^4 Solution of potassa, sp. gr. 1.26 av.oz. i 1 /^ Oil of bergamot m. 80 Oil of caraway m. 60 Oil of lavender flowers. .. .m. 40 Oil of thyme, white m. 20 Melt the tallow and oil together, cool to 50 C, add the alkaline solutions, and continue a gentle heat, stirring con- stantly for about half an hour or until the mass is homogeneous; then incor- porate the essential oils. III. Lard av.oz. 16 Spermaceti ....av.oz. 1 Caustic potash av.oz. 2 Water fl.oz. 16 Perfume to suit Melt the lard and spermaceti, dissolve the potash in half the water, and grad- ually add this solution to the melted fat, constantly stirring meanwhile. Then incorporate the remainder of the water which has previously been warmed, and finally add any desired perfume ("ex- tract," oil or synthetic), which may be dissolved in a small amount of alco- hol. This is similar to No. I but is some- what softer. Less water may be used if desired. IV. Lard av.oz. 15 Benne oil av.oz. 3 Solution of caustic potash, sp. gr. 1.384. av.oz. 7 Solution of caustic soda, sp. gr. 1.384 av.oz. i l / 2 Water fl.dr. 4 Perfume to suit Melt the lard, add the oil, and keep the mixture at a temperature of about 38 C. throughout the operation. Keep the fatty mixture in constant motion and to it gradually, first the soda solu- tion, then the potash solution, and then the water. When saponification is com- pleted, allow the mass to cool somewhat, and then incorporate any desired per- fume ("extract," oil, or synthetic) which may be first dissolved in a small amount of alcohol. Powders. V. Soap, powder av.oz. 9 Starch av.oz. i l / 2 Sodium carbonate av.oz. I Orris root, powder av.oz. Z A Oil of bergamot drops 20 The orris root may be replaced by powdered soap bark and a very little oil of orris may be added. l(M)l') THE STANDARD FORMULARY VI. Soap, powder av.oz. 10 Spermaceti, powder gr. 75 Cumarin gr. 1 Oil of wintergreen drop 1 Oil of bergamot drops 3 Mix thoroughly. DEPILATORIES. (^Hair Removers.) Depilatories are preparations for re- moving hair. They are usually in the form of powder, which should be in impalpable condition. The main or ac- tive ingredient is usually sulfid or sulf- hydrate of one of the alkalies or alka- line earths, although the older depila- tories were made with caustic alkalies. In using these depilatories they should be made into thin paste with water, applied in a thin layer to the skin, al- lowed to remain a few minutes and then scraped off with a blunt instrument, when the hair will have softened suf- ficiently to remove without pain. All these preparations give out the disagreeable odor of sulfuretted hydro- gen, strontium sulfid least so. These preparations readily lose sulfid and un- less tolerably fresh they are of little value for the removal of hair. Too long contact of depilatories with the skin should be avoided, as they are liable to cause erosions and even ugly sores. To avoid any bad after-effect, the skin should be thoroughly cleansed and then anointed with a bland oil. These preparations are used mainly for ladies for the removal of hair from the face. In the Orient women use them also to remove hair from other portions of the body as the axillae and pubis. The longer hair should be cut off with a scissors before applying the depilatory. Besides the sulfids, other preparations are used as depilatories, such as iodin in combination with collodion or sodium ethylate but the sulfids are the safest and most satisfactory for ordinary use. I. Prepare sulfuretted baryta (bar- ium sulfid) by making heavy spar (nat- ural barium sulfate) and charcoal into a stiff paste by means of linseed oil, forming this mass into cylindrical rolls and subjecting it in a crucible to the heat of a coal fire. The dark gray coke, after pulverizing, is then made up as follows : Crude sulfuretted bartya. .parts 2 Zinc oxid part 1 Starch part 1 With the aid of water this powder is converted into a soft paste and ap- j plied to a hairy skin in a layer as thick as a straw. After drying (about ten minutes), the pellicle is scraped off with a paper knife, or similar blunt instru- ment, and with it the hair. The face should be washed clean and anointed with some bland oil. Ordinary barium sulfid may be used in place of the sulfuretted bartya. The zinc oxid may be omitted if desirecA II. Another method of using bariun sulfid is as follows : Soap, powder dr. 1 Talcum dr. 7 Wheat flour dr. 7 In using, mix one teaspoonful of the powder into a paste with 3 teaspoon- fuls of water, and apply to the parts with an ordinary shaving brush in a moderately thick and even layer. After four or five minutes the parts should be moistened with a sponge, when after another five minutes, the hair can be removed by washing off the mass. For the success of a depilatory pow- der containing barium sulfid it is highly important that the sulfid be as fresh as possible and it must not have become oxidized by exposure to air. III. Calcium sulfid, also used as a depilatory, may be made by heating a mixture of 10 parts of finelv powdered lime with 9 parts of sulfur, contained in a crucible, to a low red heat. Then mix as follows: Calcium sulfid (prepared as above) parts 2 Zinc oxid part 1 Starch part 1 Reduce all to fine powder and mix HAIR AND SCALP PREPARATIONS. 1001 well. A small amount of aromatic oils, such as lemon and peppermint, may- be incorporated with this powder to disguise its odor. This should be kept in well-stoppered bottles, as like other sulfids, it is readily decomposed by the atmosphere. In using this make a paste with water, apply lightly to the skin, leave for about 10 minutes, then remove with water. IV. Calcium sulfhydrate is prepared for use as a depilatory in the following manner: Take 2 parts of freshly- slaked lime from which the gritty parti- cles have been removed and mix it with 3 parts of water. Through this pass a stream of sulfuretted hydrogen which may be made in the usual man- ner, i. e., from iron sulfid and sulfuric acid. A pasty, bluish-green mixture is obtained which is non-caustic and serves well as a depilatory. It should be pre- served in wide-mouthed amber-colored, well-stoppered bottles as the carbon dioxid of the air decomposes it quickly. It is to be applied in a thin layer to the skin by means of a satpula or spoon handle. After 5 minutes, remove it with the aid of tepid water and a towel, using gentle friction. This preparation is practically the same as the one known as Boettger's and Martin's depilatory. V. According to the specifications of a German patent, sulfuretted calcium may be employed in this form: Make a mixture of hydrated lime with a 5 to 25% sugar solution and into this pass a stream of sulfuretted hydrogen. If properly prepared an almost dry mass is obtained which should be mixed with talcum so that the mixture contains 4 to 6% of sulfid. In using, make into a paste with water, apply this lightly to the skin, allow to remain for 5 or 10 minutes, then remove by washing gently with water. VI. Another sulfid used by Oriental women is orpiment or arsenic sulfid in the following form : Quicklime parts 10 Starch parts 6 Orpiment part 1 This is to be mixed into paste with water and applied like the preceding preparations. VII. Another form of depilatory is the following: Tincture of turpentine m. 50 Oil of turpentine m. 100 Castor oil fl.dr. 2 Alcohol fl.dr. 5 Collodion, to make fl.oz. 4 In using, apply daily for several days, after which the film is removed, bring- ing the hair with it without causing pain. VIII. Sodium ethylate solution is also advised as a depilatory but it is so caustic in action that the greatest care should be exercised in its use and then it had best be used under the direction of a physician. The method of prepar- ing it according to the British Pharma- copoeia is as follows : Metallic sodium, clean and bright gr. 23 Absolute alcohol fl.oz. 1 Cautiously dissolve the sodium in the alcohol contained in a flask, the latter being kept cool by a stream of cold water. The sodium must be added in very small bits. The solution should be recently pre- pared, as it attracts moisture from the air which decomposes it. IX. Still another depilatory is Unna's Depilating Stick which is made by fusing 9 parts of rosin with 1 of beeswax. These are used like seal- ing wax; one end is softened by heat (but not hot enough to burn the skin) and is pressed gently upon the hairy skin and when cooled is jerked away, bringing the hairs with it. 1002 THE STANDARD FORMULARY CHAPTER IV. TOOTH AND MOUTH PREPARA- TIONS. Tooth preparations or dentifrices in- clude powders, creams, pastes, soaps and liquids. These will be considered in de- tail under the appropriate headings. TOOTH POWDERS. The customary ingredients are chalk (usually precipitated, sometimes pre- pared), orris root, myrrh, cuttle-fish bone, pumice stone, sodium bicarbonate, magnesium carbonate, soap, sugar, sac- charin, menthol, eucalyptol, thymol, and other antiseptics, essential oils, coloring matters, etc. All the solids must be re- duced to very fine powder, must be mix- ed intimately together and with the li- quid ingredients (volatile oils, carbolic acid, etc.), and the whole must be sifted through a very fine sieve. It will be of advantage to pass the powder repeatedly through the sieve. The principal ingredient, the one that usually forms the bulk of the product, is precipitated chalk. This acts as an abra- sive or cleansing and polishing agent and is assisted in this action by cuttle- fish bone or pumice stone if these are present. These latter two substances are considered too gritty for use in tooth preparations and are now usually omitted. Even precipitated chalk, on account of its crystalline character, is considered by some dentists as being too harsh on the tooth enamel and is fre- quently replaced by prepared chalk, which is soft and amorphous. Other substances now used as substitutes for precipitated chalk are sugar of milk and kieselguhr, as well as other white or light-colored clays. Sugar of milk is the basis of the so-called soluble tooth powders. Kieselguhr and other clays are the most modern ingredients of tooth powders, and when purchased in fairly large quantities are cheapen even than chalk. Soap is another important ingredient of tooth powders and may be present to the extent of 5 to 20%. It causes the powder to foam during use and adds to the detergent properties of the combina- tion, hence it is seldom omitted. Magnesium carbonate is sometimes added to tooth powders in the propor- tion of 1 to 5% to impart lightness and bulk but is not really necessary. Sodium bicarbonate is added in small amounts to powders to increase the alka- linity. It is a mild soluble alkali, ren- dering the secretions of the mouth tem- porarily alkaline and thus warding off the deposition of tartar. However, chalk and magnesium carbonate are sufficiently alkaline and sodium bicarbonate does not add to the pleasant taste of the powder. The same remarks will also apply to the use of borax in tooth pow- ders, although this substance is more agreeable to the taste. Sugar and saccharin are used as sweetening agents. The former is ob- jected to as being fermentable and if left in the teeth may set up a fermenta- tion. Saccharin is not so pleasant a sweetener but it is strongly antiseptic. It may be used in the proportion of about j/io%. Milk sugar has also been recommended as a sweetening agent in- stead of cane sugar. Charcoal was formerly a favorite in- gredient of tooth powders on account of supposed deodorant properties but it acts too harshly on the tooth enamel and is now usually omitted. It frequently lodged between the teeth and discolored them. It was al:o objectionable on ac- count of the color of the powder ob- tained. Orris root is a favorite ingredient of tooth powders. It is pleasant in taste and it aids in disguising the taste of the soap and chalk. Myrrh was formerly largely used in tooth powders but its taste is not agree- able. Acids, except boracic, carbolic or sali- cylic acid, should never be used in tooth powders or other tooth preparations, notwithstanding that formulas for acid TOOTH AND MOUTH PREPARATIONS. 1003 tooth powders have been published and have even been recognized by pharma- copeias. Tannin or tannin-containing drugs is sometimes added in small amount to powders for the astringent action on the gums. Tooth powders are frequently colored though just as often they are left un- colored, provided they are white or near- ly so. They are often colored a rose tint by the addition of 10 to 20 grains of carmine to the pound. This should be rubbed to a fine powder with the sugar or other gritty ingredient or, in the ab- sence of this, with a small portion of the chalk, before adding the other in- gredients. Or the carmine may be rub- bed to a paste with ammonia water, then incorporated with the remaining ingredi- ents, in the meantime allowing the am- monia to evaporate. Tooth powders may also be colored a rose or pink tint with Armenian bole or rose pink. They may also be colored other tints, such as green with chlorophyll. In the formulas given in this book the coloring matter may be added or it may be omitted, as may be desired. Among the antiseptic substances used in tooth powders are boracic acid, thy- mol, menthol, salol, eucalyptol, beta- naphtol, camphor, carbolic acid, and flavoring oils. The boracic acid, thymol, salol, menthol and camphor should be in very fine powder before being incorpor- ated with the other ingredients and they should be mixed intimately with the lat- ter. Intimate mixture will also apply to the carbolic acid and other liquids. The substances used for flavoring pur- poses should include the essential oils used for flavoring purposes rather than the ones for perfumes, such as oils of wintergreen, peppermint, cassia, lemon, orange, clove, sassafras, rose, etc. The favorites are wintergreen, peppermint and cassia, but more particularly the first two. Enough of these should be used to leave a pungent, cooling and cleanly feeling in the mouth, say about 2 to 4 fluidrams of peppermint or win- tergreen oil to the pound or about one- half as much oil of cassia as this is more pungent. Camphor, carbolic acid, menthol, thymol, eucalyptol, orris and myrrh are also to be ranked as flavors. Combinations of different oils are fre- quently used. In the formulas given be- low the flavors may be changed to suit. The most modern ingredients of tooth powders are the oxygen-yielding com- pounds including sodium perborate and calcium and magnesium peroxids. Cal- cium peroxid is known by the names calox and gorite. These substances are added to tooth powders in the propor- tion of 2 to 4%, otherwise the tooth powder is compounded in the usual man- ner. These powders when moistened with water yield hydrogen peroxid, which of course readily parts with its oxygen and acts as a bleaching agent and disinfectant. These powders are therefore especially valuable when the teeth are discolored from decay or from smoking, restoring them to their original whitness and stopping the decay. The name given varies according to composition and according to the fancy of the maker. It may be called "myrrh tooth powder," "saponaceous tooth pow- der," "camphorated tooth powder," "charcoal tooth powder," "thymol tooth powder," "carbolated tooth powder," "coral tooth powder," "pearl tooth pow- der," "rose tooth powder," "antiseptic tooth powder," "salol tooth powder," "violet tooth powder," "aromatic tooth powder," "Imperial tooth powder," "crown tooth powder," etc. In each case, the word "dentifrice" may be sub- stituted for "tooth powder." The name should be one easily re- membered. The container should be at- tractive and of such a form or shape that the preparation is of easy access. The label should be plain, not crowded, as everybody has a knowledge of the uses of a tooth preparation. 1004 THE STANDARD FORMULARY I. Precipitated chalk av.oz. 16 Oil of peppermint, Oil of vvintergreen, each ... sufficient About 2 to 4 fluidrams of the oils are required, to suit individual tastes, or one of the oils alone may be used. Mix well and sift. II. Precipitated chalk av.oz. 12 Orris root, powder av.oz. 4 Oils of orange and carda- mom, each sufficient Mix well. Use about 2 fluidrams of oil of orange and 15 drops of oil of cardamom. Or the two oils may be re- placed by oils of wintergreen or pepper- mint. III. Precipitated chalk av.oz. 16 Orris root, powder av.oz. 3 Cuttle-bone, powder av.oz. 2 White castile soap, powder. av.oz. 2 Magnesium carbonate av.oz. y 2 Oil of rose drops 16 Oil of wintergreen drops 8 Oil of peppermint drops 8 IV. Precipitated chalk av.oz. 16 White castile soap av.oz. 1 Licorice root av.oz. 1 Magnesium carbonate av.oz. 1 Reduce the soap and licorice root to fine powder and incorporate the other ingredients. Flavor as desired; it may also be colored with carmine. Licorice root is the sweetening agent instead of sugar or saccharin. V. Precipitated chalk av.oz. 22 ■ Sugar of milk av.oz. 6 Orris root av.oz. 2 White castile soap av.oz. 1 Carmine gr. 15 Oil of wintergreen fl.dr. 1 Oil of cassia m. 30 Triturate the carmine with the sugar of milk until well mixed, incoprorate the other ingredients, and sift the whole. VI. Precipitated chalk av.oz. 30 White castile soap, powder. av.oz. 4 Sodium bicarbonate av.oz. 2 Oil of peppermint fl.dr. 1 Oil of anise fl.dr. 1 Oil of eucalyptus fl.dr. t VII. Precipitated chalk av.oz. 12 White castile soap, powder. av.oz. 1 Betanaphthol dr. 1 Saccharin gr. 2 to 5 Oil of rose drops 15 Musk extract drops 10 In this powder, betanaphthol is the main antiseptic. It is odorless and leaves a pleasantly pungent taste in the mouth. VIII. Formula of the Swedish Phar- macopeia : Calcium carbonate av.oz. 10^2 Magnesium carbonate av.oz. 1 Borax, powder av.oz. 1 Oil of peppermint fl.dr. 1 Mix well, and sift. IX. Culley's formula: Sugar of milk .av.lb. 2 Oil of Ceylon cinnamon m. 5 Oil of eucalyptus m. 5 Oil of wintergreen m. 20 Oil of peppermint m. 45 This powder is entirely soluble. X. Mme. Que Vive's formula : Precipitated chalk av.oz.- 12 Orris root av.oz. 2 White castile soap av.oz. 1 Sugar av.oz. 1 Oil of wintergreen fl.dr. 1 The following is also advised : Prepared chalk, finely pow- dered av.oz. 8 Castile soap, powder av.oz. \ l / 2 Orris root, powder av.oz. 2 Sugar av.oz. 2 Oil of sassafras fl.dr. 1 Antiseptic Tooth Powder. XL All tooth powders mentioned here are antiseptic in character but the name is particularly appropriate for this one because containing the well-known antiseptic ingredients of Antiseptic So- lution of the U. S. P. : Precipitated chalk av.oz. 16 White castile soap, powder. av.oz. 1 Borax, powder dr. 3 Thymol gr. 20 Menthol gr. 20 Eucalyptol gr. 20 Oil of wintergreen m. 20 Rub the thymol and menthol with the oil and eucalyptol until liauefied, add the other ingredients, mix well, and sift. TOOTH AND MOUTH PREPARATIONS. 1005 Aromatic Tooth Powder. XII. Any of the powders for which formulas are contained herein are aro- matized but the following is different from others : Prepared or precipitated chalk av.oz. 12 Armenian bole av.oz. 1 Cardamom dr. 2 Orris dr. 2 Clove dr. 2 Cassia dr. 2 Oil of wintergreen. m. 30 Reduce the cardamom, orris, clove and cassia to fine powder, incorporate the other ingredients, mix well, and sift. Camphorated Tooth Powder. Any of the preceding tooth powders may be converted into a camphorated powder by replacing the oils or other flavoring substances with camphor gum. This should be reduced to fine powder by trituration in a mortar, first moisten- ing with a few drops of alcohol or chloroform, then incorporating the other ingredients, mixing thoroughly, and fi- nally passing through a fine sieve. The following formulas may also be used : XIII. Precipitated chalk av.oz. 16 White castile soap, powder. av.oz. 2 Camphor dr. 3 Eucalyptol m. 20 Oil of orange m. 15 Oil of peppermint m. 10 Oil of cinnamon m. 10 XIV. Precipitated chalk . . .- av.oz. 24 White castile soap av.oz. 3 Camphor av.oz. 1 Myrrh av.oz. y 2 Oil of peppermint fl.oz. 1 Mix all in fine powder like the preced- ing, and sift. Carbolated Tooth Powder. This may be made like camphorated tooth powder, adding about 2 fluidrams of liquefied carbolic acid to the pound of powder. As an antiseptic in tooth powders, carbolic acid is no longer es- teemed, there being so many other better ones, and its taste is objectionable. Charcoal Tooth Powder. XV. Orris root av.oz. 5 Myrrh av.oz. 5 Charcoal av.oz. n Precipitated chalk av.oz. 11 All should be in a very fine powder and the whole should be well mixed and finally passed through a fine sieve. Hunter's (John) Tooth Powder. XVI. Cream of tartar av.oz. 12 Alum av.oz. 2*4 Cochineal av.oz. 2 Cinnamon av.oz. 1 Sugar av.oz. 4 Mix all, reducing to fine powder, and sift. Marshall's or Hudson's Dentifrice. XVII. Prepared chalk av.oz. 12 Myrrh, powder ...av.oz. 4 Orris, powder av.oz. 4 Rose pink av.oz. % Mix well, reduce to fine powder, and sift. Mialhe's Tooth Powder. XVIII. Sugar of milk av.oz. 18 Tannin dr. 2 Rose pink gr. 80 Oil of peppermint, Oil of anise, Oil of neroli, each, enjugh to flavor suitably. Myrrh Tooth Powder. XIX. Myrrh is highly esteemed by some as an ingredient in tooth powders but is objected to on account of its after-taste. Ordinary salt disguises the taste and is itself an excellent ingredient of tooth powders. Myrrh dr. 2 x / 2 Sodium chlorid dr. 2*/ 2 White castile soap dr. iY 2 Pecipitated chalk av.oz. 16 Oil of rose, enough to flavor. Oxygenated Tooth Powder. As stated in the preliminary remarks, oxygen-yielding substances, such as so- dium perborate or calcium or magne- sium peroxid are added to tooth pow- ders for their bleaching and disinfecting properties. On contact with water, hy- 1006 THE STANDARD FORMULARY drogen dioxid is formed, and then oxy- gen is liberated in the nascent form. These substances may be added to the preceding powders in the proportion of about 4' to 6%, or the following formu- las may be used : XX. Formula of the British Pharma- ceutical Codex : Precipitated chalk av.oz. 17^2 Magnesium peroxid av.oz. 2 Powdered soap av.oz. ^ Menthol gr. 18 Oil of rose m. 45 Oil of wintergreen m. 90 Triturate the menthol with the oils, then with a s: .all portion of the chalk, add the remaining ingredients, mix well, and sift. XXI. Precipitated chalk av.oz. 12 Sodium perborate av.oz. 1 White castile soap, powder. av.oz. 1 Oil of wintergreen fl.dr. 2 Sodium perborate is not so well adapt- ed for these preparations as calcium or magnesium peroxid. Potassium Chlorate Tooth Powder. XXII. Unna recommends the use of potassium chlorate for the teeth, espe- cially in the form of paste. The follow- ing powders also contain it : Corn meal .« av.oz. 10 Potassium chlorate av.oz. \Y 2 Borax av.oz. 1 Oil of wintergreen m. 20 Oil of peppermint m. 20 All the ingredients should be in very fine powder before mixing. Then tritu- rate the borax and the oils with about half the corn meal until well mixed ; on a paper, lightly mix the potassium chlor- ate with the remainder of the corn meal by means of a wooden or horn spatula. Carefully mix the whole together and pass through a fine sieve. The silica in the seed-coats of the corn acts as an abrasive. Either white or yellow corn meal may be used but the former is of course to be preferred. Quinine Tooth Powder. XXIII. Precipitated chalk av.oz. 8 Orris root av.oz. 1 Sugar of milk av.oz. 1 Pumice stone dr. 2 Magnesium carbonate dr. 2 Tannic acid dr. \V 2 Quinine hydrochlorid gr. 20 Oil of peppermint drops 20 Oil of rose drops a, Oil of ylang ylang drop 1 Oil of bitter almond drop 1 Saccharin gr. 1 Mix all, and reduce to a fine, uniform powder. This is an example of a formula com- mon in German formularies. Rose Tooth Powder. So-called "rose tooth powders" should be flavored with oil of rose and tinted a rose color with carmine, as in the fol- lowing : XXIV. Prepared or precipitated chalk av.oz. 15 Sugar of milk av.oz. 5 Orris root, powder av.oz. 1 Carmine gr. 10 Oil of rose, natural or syn- thetic drops 10 Triturate the carmine to an impalpable condition with a small portion of the sugar of milk, then add the other ingre- dients, mix well, and sift. Salicylated Tooth Powder. XXV. Precipitated chalk av.oz. Sodium bicarbonate av.oz. Sodium salicylate dr. Orris root av.oz. Licorice root av.oz. White castile soap av.oz. Myrrh av.oz. Oil of wintergreen drops 20 Oil of rose geranium drops 2 Reduce all the solids to fine powder and mix well. It may be colored with carmine or solution of carmine if de- sired. Salol Tooth Powder. XXVI. Salol av.oz. 1 Calcium phosphate av.oz. 5 Precipitated chalk av.oz. 5 Magnesium carbonate av.oz. 5 Sodium bicarbonate av.oz. 3 Oil of peppermint fl.dr. 4 Salol may also be added to any of the preceding powders. 10/2 2V2 2 i/ 2 1 TOOTH AND MOUTH PREPARATIONS. 100? Saponaceous Tooth Powder. Most of the tooth powders contain soap but a tooth powder properly desig- nated as saponaceous should have a large proportion of soap like the follow- ing: XXVII. White castile soap, powder, .av.oz. 8 Precipitated chalk av.oz. 4 Magnesium carbonte av.oz. 2 Sugar, powder .av.oz. 2 Oil of wintergreen fl.dr. 2 Thymol Tooth Powder. XXVIII. Precipitated chalk av.oz. 15 White castile soap, powder. av.oz. 1 Thymol gr. 15 Camphor gr. 30 Saccharin gr. 10 Vanillin gr. 5 Oil of rose drops 6 Rub the camphor and thymol together in a mortar, and warm gently so as to render the mixture liquid; then add the chalk in small portions at a time, re- serving about 1 av. ounce; next add the other ingredients, the perfumes being first separately rubbed with the remain- der of the chalk. Violet Tooth Powder. XXIX. Prepared or precipitated chalk av.oz. 10 Corn starch av.oz. 4 Cuttle bone, powder av.oz. 2 Orris root, powder.- av.oz. 1 Sodium bicarbonate dr. 2 " Pumice stone, powder dr. 2 Violet extract fl.dr. 5 Color greenish with chlorophyll dis- solved in alcohol or ether. The powder should be spread out on a paper to dry before sifting. Powder for Artificial Teeth. XXX. The following has been espe- cially recommended for this purpose : Precipitated chalk av.oz. 12 Cuttle-fish bone, powder, .av.oz. 1 Corn flour av.oz. 1 White castile soap, powder. av.oz. l / 2 Carbolic acid fl.dr. 1 This may be flavored to suit. CAMPHORATED CHALK. This is a refreshing and harmless dentifrice. It should be kept in well- stoppered containers to avoid loss of camphor by evaporation. Various formulas have been given for it, varying in the proportion of the in- gredients. The following are used : I. Camphor av.oz. 1 Precipitated chalk av.oz. 9 Triturate the camphor to powder with a small quantity of alcohol, gradually incorporate the chalk, and pass through a fine sieve. II. Precipitated chalk av.oz. 9 Orris root, powder av.oz. 2 Camphor av.oz. 1 Prepare like the preceding. TOOTH CREAMS AND PASTES. These preparations differ in consist- ence, the former being rather thin, the latter being a rather hard mass. The former are dispensed in collapsible tubes, the latter in white or opal jars. Both creams and pastes may be pro- duced from tooth powders by the addi- tion of sufficient glycerin, honey or sim- ple syrup, the first mentioned being pre- ferred on account of its antiseptic prop- erty which prevents the preparation from spoiling. The creams are usually made by the use of glycerin, these re- quiring more of the diluting agent than the pastes. Creams also differ from pastes in almost invariably containing soap, which is usually incorporated in the powdered condition. In practice, these distinctions between tooth creams and pastes are not always strictly fol- lowed out, most of the so-called pastes dispensed in tubes being really creams. Most of the remarks made regarding tooth powders will also apply to tooth creams and pastes. Precipitated (or prepared) chalk is the main ingredient, which may be replaced by kieselguhr, though not with milk sugar. Soap is a necessary ingredient, and orris, pumice stone, sodium bicarbonate, magnesium carbonate and other common ingredients of the powders also enter into the com- position of creams and pastes. These 1008 THE STANDARD FORMULARY may also be made antiseptic, sweetened, flavored and colored like the powders. The oxygen-yielding compounds are not suitable for use in tooth creams and pastes as they decompose in the presence of moisture. As in the case of tooth powders, the solid ingredients should be reduced to very fine powder, be well mixed, and then passed through a fine sieve, after which the "massing" substance (glyce- rin, etc.) may be added. The powder must be thoroughly incorporated with the "massing" liquid, which may be ac- complished by beating in a large mortar like making a pill mass. Or, for large quantities a bread mixer, putty" machine or other apparatus may be employed. As regards the "massing" agent, glyc- erin is more suitable than honey and the latter more so than simple syrup, but glycerin is objectionable because it is liable to separate from the mixture and ooze out from the container and over the label. A better "massing" agent is glycerite of starch or a glycero-gelatin mixture, to which saccharin may be add- ed to intensify the sweetness produced by the glycerin. The following "mass- ing" fluid may be used with any mix- ture of powders. Gelatin dr. i Water fl.oz. 2 Glycerin fl.oz. 6 Dissolve the gelatin in the water by the aid of a gentle heat and add the glycerin. To make a soft cream more of this liquid must be used than if a hard paste is to be prepared. To fill collapsible tubes with tooth cream, a large glass or hard rubber syringe may be used, or for large quantities, a so-called sausage- stuffing machine may be employed. Flavors. The flavoring for tooth creams may be oil of peppermint or of wintergreen or any of the combinations directed for tooth powders. Or the following com- binations will prove acceptable : Oil of eucalyptus m. 6o Oil of peppermint m. 30 Oil of rose geranium m. 30 Oil of clove m. 30 Oil of anise drops 10 II. Oil of rose m. 20 Oil of cinnamon m. 40 Oil of lemon - fl.dr. 2^ Oil of clove fl.dr. 3 Tincture of vanilla fl.oz. 1 III. Oil of lemon fl.dr. 1 Oil of clove fl.dr. 1 Oil of peppermint fl.dr. 4 Tincture of benzoin fl.dr. 2 IV. Oil of pimento m. 25 Oil of sage m. 40 Oil of clove fl.dr. 2 Oil of peppermint fl.dr. 4 Suitable names for tooth pastes and creams are the following: "Menthol glycerin tooth cream (or paste)," "Cas- tilian tooth cream (or paste)," "Persian tooth cream (or paste)," "cherry tooth cream (or paste)," "creta cream (or paste)," "Oriental tooth cream (or paste)," "saponaceous tooth cream (or paste)," "damask rose tooth cream (or paste)," "eucalyptus tooth cream (or paste)," "coca tooth cream (or paste)," "coral tooth cream (or paste)," "salicy- lated tooth cream (or paste)," "odon- tine," "rose tooth cream (or paste)." "kalodont," "salol tooth cream (or paste)," "thymol tooth cream (or paste)," "violet tooth cream (or paste)," "dentine," "dentalba," "dental cream (or paste)," "antiseptic tooth cream (or paste)," "carbolated tooth cream (or paste)," "camphorated tooth cream (or paste)," "charcoal tooth paste," "ruby tooth cream (or paste)," "myrrhine tooth cream (or paste)," "Vienna tooth cream (or paste)," etc. The word "den- tifrice" may in each instance be substi- tuted, if desired, for the word "tooth" or for the phrase "tooth cream" or "tooth paste." I. Blair's formula : Soft (green) soap av.oz. 2 Starch av.oz. I TOOTH AND MOUTH PREPARATIONS. 1009 Water fl.oz. i Glycerin fl.oz. 16 Precipitated chalk fl.oz. 16 Oil of peppermint fl.oz. i Triturate the starch with the water and glycerin to a smooth mixture and heat with constant stirring to form a glycerite of starch. With this incorpor- ate the soap, chalk and oil (and coloring if desired), beating all ingredients to- gether so as to form a smooth paste. II. Culley's formula : Precipitated chalk av.oz. 8 Prepared chalk av.oz. 8 White castile soap, powder. av.oz. y 2 Thymol . ._ gr. 3 Oil of cassia m. 5 Oil of sassafras m. 15 Oil of wintergreen m. 45 Alcohol fl.dr. 2 Solution of carmine, N. F., enough to color pink. Mix well and make a paste or cream by adding enough of this mixture: Gelatin gr. 30 Water fl.oz. 2 Glycerin fl.oz. 4 Saccharin gr. 4 Instead of using two kinds of chalk, either one alone in double amount may be used. III. Formula of the Swedish Pharma- copeia : Precipitated chalk av.oz. 13 White castile soap, pow- der av.oz. 4 Glycerin av.oz. 3 Oil of peppermint m. 100 IV. Mme. Qui Vive's formula : Precipitated chalk av.oz. 8 Orris root, powder .av.oz. 8 White castile soap, powder, .av.oz. 2 Borax, powder av.oz. 2 Myrrh, powder av.oz. 1 Mix well, and add honey and glycerin, each, equal parts, to make a paste. Color slightly with carmine and flavor with wintergreen. V. Precipitated chalk av.oz. 16 White castile soap av.oz. 1 Gelatin av.oz. Yi Saccharin gr. 15 Menthol gr. 30 Oil of eucalyptus fl.dr. 1 Oil of wintergreen or cassia. fl.dr. 3 Glycerin fl.oz. 16 Water fl.oz. 16 Triturate the oils, menthol and sac- charin together and gradually incorpor- ate the chalk until the whole is well mixed. Also soak the gelatin in half the wa- ter, previously heated, until thoroughly softened. Dissolve the soap in the re- mainder of the water by the aid of heat, stirring frequently, and replacing, from time to time, the water lost by evaporation. Mix the gelatin and soap solutions and incorporate with the chalk mixture. If a soft cream for collapsible tubes is desired, use 19 or 20 fluidounces of the "massing" mixture and if a hard paste for jars is wanted, use only 12 fluidounces of the "massing" mixture, in which case an especially thorough beating in a mortar will be necessary. The preparation may be colored either pink or dark red if desired by the addi- tion of cochineal coloring or solution of carmine of the N. F. The soap used should be the fresh (moist) kind, which may be grated from the large bars or cakes. VI. Precipitated chalk av.oz. 19 Soap, powder av.oz. 3 Sugar, powder av.oz. 5 Saccharin gr. 5 Thymol >...gr. 10 Oil of peppermint m. 20 Oil of cinnamon m. 20 Solution of soda fl.oz. 4 Glycerin fl.oz. 3 Water fl.oz. 3 Make a cream or paste in the usual manner. The solution of soda is said to prevent hardening of the cream in the course of time. Arnica Tooth Paste. VII. Precipitated chalk av.oz. 12 White castile soap, powder. av.oz. 4 Cuttle bone, powder av.oz. 2 Tincture of arnica fl.oz. 2 Solution of carmine, N. F.. fl.dr. I Oil of peppermint fl.dr. I Oil of sassafras fl.dr. 4 Glycerin fl.oz. 4 Water, enough to make a paste or cream. 1010 THE STANDARD FORMULARY Camphorated Tooth Paste. VIII. Culver's formula : Any of the preceding may be convert- ed into a tooth paste by replacing the flavor with camphor, or the following may be used : Precipitated chalk av.oz. 13 Cuttle bone, powder av.oz. 3 White castile soap, powder. av.oz. 2 Vanillin gr. 5 Saccharin gr. 10 Thymol gr. 15 Camphor gr. 30 Oil of peppermint m. 20 Oil of wintergreen gr. 40 Make into a paste or cream with a mixture of 4 oarts of glycerin and 1 part of water. Harlan's Tooth Paste. IX. Precipitated chalk av.oz. 8 Orris root, powder av.oz. 8 White castile soap, powder, .av.oz. 2 Borax, powder av.oz. 2 Myrrh, powder av.oz. 1 Honey, glycerin, each sufficient to form a soft paste. Carmine, enough to color. Perfume, to suit. Menthol Tooth Cream. X. Precipitated chalk av.oz. 8 White castile soap, powder. av.oz. 4 Magnesium carbonate av.oz. 2 Menthol (dissolved in some alcohol). Solution of carmine, Glycerin, each sufficient Rub the first three ingredients into a paste with glvcerin, then flavor and color to suit with the menthol and carmine solutions. Peroxid Tooth Cream. XI. Kuehl's formula: Precipitated chalk av.oz. 10 Soap, powder av.oz. 2 Hydrogen peroxid, Glycerin, each, to form a suitable cream. Flavor with oils of peppermint and lavender flowers. Potassium Chlorate Tooth Paste. XII. According to Unna, potassium chlorate is a most valuable ingredient of tooth preparations. It is stated to exer- cise marked tonic properties on the teeth, gums and tonsils, acting favorably on mercurialized gums. It acts best in the form of a tooth paste containing 50% of this salt, such as the following: Potassium chlorate av.oz. 10 Precipitated chalk av.oz. 2 Magnesium carbonate av.oz. 2 Sugar av.oz. 1 Soap, powder av.oz. */> Glycerin fl.oz. 1 Water fl.oz. 3 Thymol gr. 30 Vanillin gr. 30 Oil of peppermint fl.dr. 2 Reduce all to fine powder and make a paste in the usual manner. Salicylated Tooth Paste. XIII. Precipitated chalk av.oz. 16 White castile soap, powder. av.oz. 4 Sugar, powder av.oz. 4 Orris root, powder av.oz. 4 Pumice stone, powder av.oz. 1^2 Sodium salicylate gr. 80 Glycerin fl.oz. 2 Carmine or solution of car- mine sufficient to color Water enough to form a mass Mix well and perfume with oil of pep- permint, wintergreen or other oil. Thymol Tooth Paste. XIV. Precipitated chalk av.oz. 16 Magnesium carbonate av.oz. 1 Orris root, powder av.oz. 3 Thymol dr. 1 Mix well and make a mass with suf- ficient of the following mixture : Gelatin, pure gr. 70 Glycerin fl.oz. 3 Water fl.oz. 1 Dissolve by the application of a gentle heat. TOOTH SOAPS. It is not likely that very many phar- macists will care to undertake the man- ufacture of tooth soap as this requires the experience of a professional soap maker. However, a few hints and for- mulas will not be amiss. Tooth soaps partake of the general character of tooth creams and pastes but are much harder. They may be put up in the form of round sticks or flat cakes like camphor TOOTH AND MOUTH PREPARATIONS. 1011 ice. These may be wrapped in oiled paper or tin-foil. Or the soap may be dispensed in flattened tin boxes. In us- ing, the moistened brush is first rubbed against the stick or cake. The composition of tooth soap is largely like that of a tooth paste but must contain at least 20% or soap. Flav- oring, coloring and antiseptic agents must be added as in the case of creams and powders. The "massing" agent had best contain considerable alcohol so that the product will dry harder and more quickly. I. Talcum, powder av.oz. 10 Pumice stone, powder av.oz. H Orris root, powder.. av.oz. 2 Mix well and color with carmine if a pink or red color is desired, and with chlorophyll, if a green color is desired, and flavor with a mixture consisting of Oil of peppermint fl.dr. 2 Oil of sage fl.dr. 1 Oil of calamus m. 50 Oil of thyme, white m. 25 Cumarin gr. 15 Also mix White castile soap, powder. av.oz. 10 Alcohol fl.oz. 5 Glycerin fl.oz. i l / 2 Beat together to form a soft paste, and then gradually incorporate the pre- vious mixture of powders. Press the mass into molds, and, after removing the cakes, brush the latter over with tincture of benzoin containing a little oil of peppermint. When dry, cover with tin-foil. The mass may also be pressed into tin boxes and allowed to dry in the latter. II. White castile soap, powder. av.oz. 10 Talcum, powder av.oz. 4 Pumice stone, powder av.oz. 2 Cuttle-fish bone, powder. . .av.oz. 2 Sodium carbonate, dried dr. 3 Cochineal, powder ...dr. i>4 Diluted alcohol fl.oz. 1 Glycerin fl.dr. 6 Oil of peppermint fl.dr. 2 Rose water sufficient Mix the soap, talcum, pumice and cut- tle-fish bone, then add the cochineal pre- 64 viously triturated to a fine powder. Hav- ing mixed these ingredients thoroughly, add the soda, alcohol and glycerin, stir- ring well, incorporate the oil, and then add enough rose water to form a mass. Divide into pieces or press into boxes, and allow to dry. TOOTH WASHES. (Liquid Denti- frices.) These are preparations made from quillaja or soap, and are colored and flavored. They replace the tooth pow- ders, pastes, creams and soaps. They may be known by such titles as "eudonto," "quillaja tooth wash," "kal- liodont," "odontine," "saponaceous tooth wash," "aromatic dentifrice," "dento- line," "antiseptic liquid dentifrice," "al- mond tooth essence," "Oriental tooth wash," "carbolated tooth wash," "cam- phorated tooth wash," etc. See also under heading Mouth Washes. Saponaceous Tooth "Washes. These consist of a solution of soap, usually white castile, sometimes soft soap U. S. P., in a mixture of alcohol and water, the whole being flavored like the powders and creams. The prepara- tions should be filtered clear and bright before bottling. Before filtering they should be set aside for several days in a cool place to permit all the excess of stearin and palmitin to precipitate. I. Styles' formula No. 1 : White castile soap, powder. av.oz. 1^2 Camphor dr. 1 Oil of rosemary m. 15 Alcohol fl.oz. 8 Water, to make fl.oz. 30 Mix all, stir frequently until the soap is practically all dissolved, and filter. II. Styles' formula No. 2: White castile soap, powder. av.oz. 2 Orris root, powder av.oz. 1 Cochineal dr. 2 Oil of wintergreen fl.dr. 1 Oil of peppermint fl.dr. 1 Oil of lemon fl.dr. 2 Glycerin fl.oz. 2 Alcohol fl.oz. 32 Mix, macerate for 2 days, agitating frequently, and filter. 1012 THE STANDARD FORMULARY III. Culley's formula: White castile soap, powder. av.oz. >4 Oil of eucalyptus drops 8 Oil of cassia drops 20 Oil of wintergreen drops 40 Thymol gr. 4 Menthol gr. 4 Resorcin gr. 8 Glycerin fl.oz. 4 Alcohol fl.oz. 12 Water fl.oz. 20 Solution of carmine, enough to color. Dissolve the oils, thymol and resorcin in the alcohol, add the glycerin, then the water, and coloring matter, let stand for a day or two, agitating frequently, then filter, first cooling to 40 F. IV. Te-Linde's formula: White castile soap av.oz. 2 Oil of clove m. 20 Oil of peppermint m. 40 Oil of wintergreen m. 60 Tincture of vanilla fl.dr. 6 Solution of carmine fl.dr. 2 Glycerin fl.oz. 6 Alcohol fl.oz. 14 Water, to make fl.oz. 32 Dissolve the soap, in shavings, in 8 fluidounces of boiling water, and the oils in the alcohol. Mix these, add the other ingredients, and filter clear. V. Parker's formula : White castile soap av.oz. 4 Glycerin fl.oz. 4 Water fl.oz. 8 Alcohol fl.oz. 16 Oil of peppermint drops 20 Oil of wintergreen drops 50 Cochineal coloring, enough to color. Dissolve the soap in the mixed glyce- rin, water and alcohol, add the oils and coloring, and filter. VI. Thayer's formula: White castile soap, powder. av.oz. V/2 Thymol gr. 12 Oil of clove drops 15 Oil of orange drops 15 Oil of rose drops 15 Oil of wintergreen drops 15 Glycerin fl.oz. 3 Alcohol fl.oz. 12 Water fl.oz. 18 Prepare in the usual manner. The preparation may be colored red with cochineal coloring or solution of car- mine, N. F., or green with chlorophyll. VII. Caldwell's formula: Tincture of green soap fl.oz. 4 Oil of clove m. 5 Oil of cassia m. 5 Oil of peppermint m. 30 Oil of wintergreen m. 30 Glycerin fl.oz. 4 Alcohol fl.oz. 12 Water ..fl.oz. 12 Compound tincture of cochi- neal, to color. Mix all the ingredients, let stand for 24 hours, and filter. The soap for the tincture must be soft, almost neutral, and entirely free from odor. The tincture of cochineal is to be made according to this formula : Cochineal, bruised av.oz. 1 Potassium carbonate gr. 70 Diluted alcohol, to make. .. .fl.oz. 4 Mix, macerate, and filter. Quillaja Tooth Washes. In the following preparations, the foaming and cleansing agent is soap bark, which may be in the form of in- fusion, tincture, or fluid extract. This preparation may be flavored, colored or made antiseptic like the saponaceous tooth washes. VIII. Thayer's formula: Infusion of quillaja (1 :io) .fl.oz. 16 Infusion of red rose petals (1 :io) fl.oz. 4 Tincture of myrrh fl.oz. 1 Liquefied carbolic acid drops 25 Menthol gr. 6 Oil of clove drops 4 Oil of neroli drops 4 Oil of peppermint drops 4 Oil of wintergreen drops 8 Oil of rose geranium drops 12 Glycerin fl.oz. 4 Alcohol fl.oz. 10 Tincture of cudbear, to color. Dissolve the oils and menthol in the alcohol, add the other ingredients, let stand for a week, and filter through magnesia. IX. Edel's formula: Fluid extract soap bark fl.oz. 4 Oil of clove drop 8 Oil of wintergreen drops 16 Glycerin fl.oz. 8 Alcohol fl.oz. 8 Water fl.oz. 12 Tincture of cudbear, to color. TOOTH AND MOUTH PREPARATIONS. 1013 Mix and filter. Or the preparation may be made from the ground soap bark by percolation. X. Styles' formula: — Soap bark, coarse powder, .av.oz. 4 Benzoic acid dr. 2 Thymol gr. 15 Oil of wintergreen m. 10 Oil of eucalyptus m. 15 Glycerin fl.oz. 1 Alcohol fl.oz. 16 Water, to make fl.oz. 32 Mix all, macerate for 7 days, agitating occasionally, and filter. XL Taylor's formula: Soap bark, ground av.oz. 4 Sodium salicylate av.oz. Yi Oil of clove drops 20 Oil of bergamot fl.dr. 1 Oil of wintergreen fl.dr. 1 Alcohol fl.oz. 2 Glycerin '. fl.oz. 3 Diluted alcohol, to make fl.oz. 32 Solution of carmine, enough to color. Extract the bark by percolation with diluted alcohol mixed with glycerin. In the alcohol dissolve the oils, mix this with the percolate, add the other ingre- dients, filter, apd pass, if needed, enough diluted alcohol through the filter to make 32 fluidounces of product. XII. Harnist's formula: Quillaja, coarse powder. . .av.oz. 2 Oil of clove drops 10 Oil of wintergreen drops 30 Tincture of vanilla fl.dr. 4 Glycerin fl.oz. 2 Alcohol fl.oz. 8 Rose water fl.oz. 32 Solution of carmine, N. F. . fl.dr. i l / 2 Dissolve the oils in the alcohol, add the other ingredients, macerate for 2 weeks, agitating occasionally, and filter. MOUTH WASHES. (Collutories.) These are preparations intended for cleansing, purifying and deodorizing the mouth, and frequently also for cleansing the teeth. They serve the purpose of arresting decay, neutralizing bad breath, and relieving inflamed mucous mem- brane. Before use, they are usually di- luted with water, about 1 teaspoonful being added to a cupful of the latter. They always contain antiseptic and flav- oring constituents, sometimes also an astringent substance like tannic acid, kino, rhatany, oak bark, etc., and fre- quently also a coloring constituent. They are usually dispensed under such names as "prophylactic tooth and mouth wash," "dentifrice elixir," "thy- mol dentifrice," "salol mouth wash," "aromatic mouth wash," "astringent mouth wash," "tooth tincture," "mouth essence," "elixir of roses," "violet mouth wash," "rubicreme," "favorite tooth and mouth wash," "mentholated dentifrice," "mentholine tooth wash," "eau denti- frice," "Imperial mouth wash," "sali- cylic mouth wash," "eau angelique," "carbonated tooth wash," "mouth water," etc. Excellent mouth washes are Antisep- tic Solution, U. S. P., and Alkaline An- tiseptic Solution, N. F. I. Menthol gr. 8 Saccharin gr. 15 Borax dr. 2 Solution of potassa fl.dr. 4 Oil of eucalyptus drops 10 Oil of wintergreen or cassia.. m. 15 Alcohol fl.oz. 4 Water, to make fl.oz. 16 Dissolve the oils and menthol in the alcohol, the borax in the water, mix, add the other ingredients, shake until dis- solved, and filter. Color if desired with compound tincture of cudbear. II. Boric acid dr. 6 Oil of peppermint drops 20 Oil of cassia dr. 2 Carbolic acid fl.dr. 2 Chloroform fl.dr. 2 Alcohol fl.oz. 7 Glycerin, to make fl.oz. 16 Mix, dissolve by agitation, and filter. Put a teaspoonful to a glassful of water as a mouth wash. III. Oil of clove m. 5 Oil of spearmint m. 15 Oil of peppermint m. 30 Oil of red cedar wood m. 60 Tincture of myrrh fl.oz. 1 Tincture of cochineal to color Alcohol, to make fl.oz. 16 101-1- THE STANDARD FORMULARY IV. Formula of the German Hos- pital (Phila.) : Antiseptic solution fl.oz. I Hydrogen peroxid fl.oz. I Saturated solution of po- tassium chlorate fl.oz. I Distilled water fl.oz. I V. Formula of the French Codex: Oil of cinnamon m. 15 Oil of anise m. 30 Oil of clove m. 30 Oil of peppermint fl.dr. 2 Tincture of benzoin fl.dr. 2 Tincture of guaiac fl.dr. 2 Tincture of pellitory fl.dr. 2 Tincture of cochineal fl.dr. 5 Water fl.oz. 6 Alcohol, to make fl.oz. 32 Mix, let stand for 24 hours, and fil- ter. VI. Mine. Qui Vive's formula: Myrrh, powder av.oz. 1 Borax, powder av.oz. 1 Red saunders av.oz. 1 Sugar av.oz. 1 Cologne water fl.oz. 6 Water fl.oz. 9 Alcohol fl.oz. 18 Mix, macerate for several days, and filter. Acetanilid Dentifrice. VII. Acetanilid dr. 5 Oil of peppermint drops 30 Oil of rose geranium drops 30 Tincture of cochineal m. 30 Glycerin fl.oz. 2 Alcohol fl.oz. 14 Mix, dissolve, and filter. In using, add a teaspoonful to half a glass of water. Carbolic Mouth Wash. VIII. Carbolic acid fl.dr. 2 Oil of clove m. 5 Tincture of rhatany m. 40 Tincture of cudbear fl.dr. 2 Tincture of quillaja fl.oz. 1 Glycerin > fl.dr. 6 Peppermint water fl.oz. 2 Rose water fl.oz. 12 Mix and filter. Chinosol Mouth Wash. IX. Chinosol gr. 5 Oil of cinnamon dorps 10 Oil of peppermint fl.dr. 1 Tincture of cochineal m. 100 Tincture of Siam benzoin. fl.dr. 10 Alcohol fl.oz. 15 Mix, dissolve and filter. Eau Anatherine. X. Myrrh gr. 80 Clove gr. 50 Red saunders gr. ^o Guaiac wood gr. 30 Cassia bark gr. 30 Oil of clove drops 5 Oil of cassia drops 5 Rose water fl.oz. 5 Alcohol fl.oz. 12 Reduce all the drug to coarse powder, macerate for 7 days, agitating occa- sionally, and filter. Eau de Botol This is an old French preparation specially for which various formulas are offered, among them the following: XI. Star anise dr. 6 Cassia dr. 2^2 Clove dr. 2^/2 Cochineal gr. 36 Oil of peppermint m. 40 Oil of rose drops 5 Water fl.oz. 4 Alcohol fl.oz. 12 Mix the drugs, reduce to coarse pow- der, add the alcohol and water, macer- ate for 7 days, agitating occasionally, filter, and add the oils. The drugs may also be extracted by percolation. Formaldehyde Mouth Wash. XII. Formaldehyde dr. 4 Tincture of benzoin fl.oz. 2 Tincture of myrrh fl.dr. 4 Oil of peppermint m. 15 Oil of anise m. 10 Oil of cinnamon m. 5 Alcohol fl.oz. 12 Cochineal, powder gr. 10 Mix, macerate for several days, and filter. Salol Mouth Wash. XIII. Formula of the British Pharm- aceutical Codex: Salol dr. 3 Thymol gr. 20 Oil of peppermint m. 40 Spirit of anise m. 80 Solution of saccharin fl.dr. 3 Alcohol, to make fl.oz. 16 TOOTH AND MOUTH PREPARATIONS. 1015 Dissolve the salol and thymol in 8 fluidounces of alcohol, heating gently if necessary, add the other ingredients, and filter. In using, add a few drops to a wine- glassful of water. XIV. Saccharin gr. 3 Salol dr. 5 Oil of thyme drops 3 Oil of peppermint m. 40 Tincture of vanilla fl.oz. 3 Alcohol, to make fl.oz. 20 Mix, dissolve and filter. Thymol Mouth Wash. XV. Thymol gr. 75 Oil of peppermint m. 75 Tincture of myrrh fl.dr. 6 Alcohol, to make fl.oz. 16 Mix, dissolve and filter. Tincture of Myrrh and Borax. XVI. Formula of the British Pharm- aceutical Codex: Tincture of myrrh fl.oz. 6 Tincture of rhatany fl.dr. 5 Oil of neroli drops 10 Oil of bergamot m. 15 Oil of lemon m. 15 Oil of , orange m. 15 Oil of rosemary m. 15 Borax, powder dr. . 3 Glycerin fl.dr. 6 Alcohol, to make fl.oz. 16 Dissolve the borax in the glycerin by the aid of heat, allow to cool, add the alcohol, oils, and tinctures, and filter. This is used to make a mouth wash — about 1 in 20 with water — for spongy gums and aphthous ulceration. Violet Mouth Wash. XVII. Oil of bitter almonds drops 5 Glycerin fl.dr. 1 Stronger tincture of orris. . .fl.oz. 2 Spirit of rose fl.oz. \ l /z Alcohol, to make fl.oz. 16 Mouth Washes for Infants. In case of canker sore mouth in in- fants, it is of advantage to cleanse the mouth with a suitable antiseptic solu- tion. This solution is also useful be- fore feeding especially when there is vomiting. The following may be used: XVIII. Boric acid dr. 1 Hydrogen peroxid fl.oz. 2 Glycerin fl.oz. I Rose water fl.oz. 3 Mix, dissolve, and filter. XIX. Oil of peppermint m. 20 Oil of clove m. 10 Oil of wintergreen m. 10 Glycerin fl.oz. I Distilled water fl.oz. 5 Mix and filter. CACHOUS. (Breath Perfumes.) These consist of various aromatics combined with licorice extract, some- times sugar, the whole being formed into a mass which may be divided into pellets, or it may be rolled out in a thin sheet and cut into little squares, or it may be rolled out into a very thin pill "pipe" about the size of a knitting needle, which may then be cut into short sections. After dividing the mass, the particles may be dried. If desired, the pellets may be silver-coated. I. Oil of peppermint drops 25 Oil of lemon drops 15 Oil of neroli drops 15 Oil of cinnamon drops 15 Clove .dr. y 2 Cardamom dr. 1 Vanilla dr. iY 2 Orris root dr. 2 Mace dr. 5 Sugar dr. 4 Licorice extract, powder. . .av.oz. 1 Mucilage of gum arabic ... sufficient Reduce the drugs to powder, add the remaining ingredients, make a mass and divide into pills weighing 1 grain each, or roll out flat and cut into small pieces. II. Musk gr. i Civet , gr. 1 Oil of vetivert drop 1 Oil of rose drops 5 Carmine gr. 5 Tartaric acid gr. 10 Gum arabic av.oz. 2 Sugar av.oz. 8 Mix the ingredients intimately form- ing a powder, add enough water to make a dough, and make into pellets. loifi THE STANDARD FORMULARY III. Musk gr. I Clove dr. i Cardamom dr. 2 Nutmeg dr. 2 l / 2 Vanilla dr. 3 Orris dr. s l / 2 Oil of cinnamon drops 8 Oil of neroli dorps 16 Oil of lemon m. 30 Oil of peppermint m. 50 Sugar av.oz. 1 Licorice extract av.oz. 2 Reduce the drugs to fine powder, add the remaining ingredients, mix well, make a mass with the water, and form into pellets, or roll the mass out and cut into very small pieces. IV. Oil or clove m. 15 Oil of peppermint m. 45 Tincture of ambergris m. 15 Tincture of musk m. 15 Orris root dr. 1 Mastic dr. 1 Cascarilla dr. 1 Gum arabic dr. 3 Catechu dr. 4 Licorice extract av.oz. 4 Reduce all the solids to powder, in- corporate with the liquids, make a mass with water, and divide into pills which may be coated with silver. CHAPTER V. BATH, FOOT AND MANICURE PREPARATIONS. BATH POWDERS. Some of the formulas mentioned be- low furnish effervescent preparations, others are non-effervescent. These pow- ders render hard water soft. I. Tartaric acid av.oz. 10 Sodium bicarbonate av.oz. 12 Starch or rice flour av.oz* 6 A few spoonfuls of this when stirred into a bathtubful of water cause a copi- ous liberation of carbon dioxid, which is thought by some to be "refreshing." The amount of sodium bicarbonate may be increased or some borax or potassium or sodium carbonate may be added if a more alkaline preparation is desired. Perfume may be added to this pow- der, volatile oils being a good form. Oil of lavender flowers would be a suit- able addition in the proportion of a fluidram or more to the av. pound of powder. A better but more expensive perfume may be obtained by mixing 1 part of oil of rose geranium with 6 parts of oil of lavender flowers An- other good mixture is 2 parts of oil of neroli and 1 part of oil of rosemary. A perfume still more desirable may be had by adding a mixture of the oils from which cologne water is made. For an ordinary quality the following will suffice : Oil of lavender flower fl.dr. I Oil of rosemary fl.dr. 1 Oil of bergamot fl.dr. 2 Oil of lemon fl.dr. 4 Oil of clove drops 8 For a better quality the following may be used: Oil of neroli fl.dr. Oil of cedrat fl.dr. Oil of orange fl.dr. Oil of rosemary fl.dr. Oil of bergamot fl.dr. A fluidram or more of either of these mixtures may be used to the pound, as in the case of lavender. The following perfume is also fine : Heliotropin gr. 15 Oil of pimento m. 15 Oil of linaloe m. 15 Oil of lemon m. 30 Oil of lavender flowers m. 30 Oil of bergamot fl.dr. 3 IT. Sodium carbonate, monohy- drated av.oz. Tartaric acid av.oz. Orris root, powder av.oz. Oil of lemon fl.dr. Oil of orris or solution of ionone m. Oil of ylang ylang m. 8 3 1 1 10 10 Mix well. To be used like No. I. III. Sodium bicarbonate av.oz. 12 Borax av.oz. 12 Potassium carbonate dr. 3 Ammonium chlorid dr. 3 Oil of anise m. 30 Oil of clove m. 30 Oil or sassafras m. 30 Oil of wintergreen m. 30 BATH, FOOT AND MANICURE PREPARATIONS. 1017 av.oz. 12 , av.oz. 4 Oil of bergamot m. 30 Oil of rose geranium m. 30 Oil of lavender flowers m. 30 Mix the salts thoroughly with the oils and keep the product in well-stop- pered wide-mouthed bottles. IV. Borax Sodium bicarbonate... -Potassium carbonate av.oz. 2 Oil of rosemary m. 30 Oil of orange fl.dr. 1 Oil of lavender flowers fl.dr. 2 Or any of the perfumes mentioned in Nos. I, II or III may be used. In using, mix a tablespoonful with the bath or a half teaspoonful with a basinful of water. BATH TABLETS. These are used in the same manner, for similar purposes, and have the same composition as the preceding bath pow- ders. The effervescent powders may be converted into tablets by making into a mass by means of alcohol, then form- ing into tablets of suitable size, and dry- ing. The non-effervescent powders may be made into tablets in the same man- ner by means of water. BATH SOAP PASTE. Soft (green) soap av.oz. 16 Glycerin fl.oz. 2 Alcohol fl.oz. 1 Perfume to suit Mix the soap, glycerin and alcohol and add the perfume. A light-colored, nearly odorless soft soap should be used. The perfume may be any oil or mixture of oils such as are used in formulas No. I, II or III under Bath Powders. The mixture may be dispensed in jars or wide-mouthed bottles. It is to be used for the same purposes as bath powders or tablets. BATH BAGS. (Mme. Qui Vive's For- mulas.) I. Violet Bath Bags: Oatmeal, finely ground lb. 2 Orris root, powder ..oz. 4 Almond flour oz. 3 White castile soap, shaved fine cake 1 Take one yard of cheesecloth and make it into little bags about 4 inches square and fill them with this mixture. Larger bags may be made for the reg- ular bath. II. Quireda Bath Bags: Fine oatmeal lb. 1 New clean bran pint 1 Orris root, powder lb. % Almond meal lb. % White castile „soap, dried oz. 4 Primrose sachet powder oz. 1 The bags should not be used a sec- ond time as the mixture in them has tendency to sour. PERFUMED SEA SALT. Stanislaus' formula: Ordinary sea salt av.lb. 5 Cumarin dr. 3 Oil of bergamot dr. 1 Anisic aldehyde m. 30 Mix the perfumes together, then pour over the salt, mixing well by rub- bing between the hands. A more convenient way of doing is to dissolve the perfumes in alcohol be- fore mixing with the salt. ARTIFICIAL SULFUR BATHS. Sulfur baths ordinarily are made by simply dissolving potassium sulfuret (sulfurated potassa) in water, in the proportion of from ^2 av. ounce to 2 av. ounces for every 40 gallons of water. But, in order to obtain a bath more closely resembling some of the more noted natural sulfurous springs which have proven so effectual in the treat- ment of rheumatism and skin diseases of certain types, the following is ad- vised : Sulfurated potassa or soda. av.oz. J A Sodium bicarbonate av.oz. 1 Sodium chlorid gr. 60 Castile soap shavings gr. 30 Calcium carbonate gr. 30 Alum gr. 30 Water gal 1 These various materials are boiled in a sufficient quantity of the water to dissolve them, and the solution is stir- red about with a wooden or glass rod until an odor of sulfuretted hydrogen 1018 THE STANDARD FORMULARY becomes manifest. The solution is then poured into the patient's ordinary water bath, previously heated to about 35° C. BATHING SALTS. Popular faith in mineral water baths is quite strong and a variety of salt mixtures to make artificial waters for bathing purposes should prove a profit- able addition to the pharmacist's stock. These salts will consist of suitable in- gredients mixed with considerable pro- portion of salt which adds the requisite bulk. These preparations may be put up in one-pound round paper boxes or in cans. On the label are to be printed directions for use, remarks upon tem- perature of the water, hygienic rules, medicinal uses, etc. The following variety of bathing salts is advised : i. A sea salt as a bracing and in- vigorating bath. 2. An acid bath for liver, indiges- tion, spleen and bowel troubles, etc. 3. An alkaline bath for rheumatism, gout, kidney troubles, etc. 4. An alternative bath for blood dis- eases, etc. 5. A sulfur bath for skin diseases, etc. 6. A tonic bath for chlorosis, anaemia, loss of appetite, etc. Sea Bath Salt. I. Potassium iodid gr. 10 Potassium bromid gr. 20 Sodium bicarbonate av.oz. 1 Magnesium sulfate av.oz. 2 Salt, to make av.oz. 16 Have all the salts in a coarse gran- ular condition and mix. Acid Bath Salt. II. Tartaric acid av.oz. 1 Potassium bicarbonate av.oz. 1 Potassium bitartarate av.oz. 2 Salt av.oz. 12 Mix as in No. I. Alkaline Bath Salt, ill. Sodium bicarbonate av.oz, 6 Sodium sulfate, Salt Mix as in No. I. .av.oz. 2 .av.oz. 8 Alterative Bath Salt. IV. Iodin, crystal gr. 20 Potassium iodid dr. 2 Sodium bicarbonate av.oz. 2 Salt av.oz. 14 Rub the iodin and potassium iodid together, add the sodium bicarbonate, and mix with the salt. Sulfur Bath Salt. V. Sulf urated potassa av.oz. Magnesium sulfate av.oz. Sodium bicarbonate av.oz. Salt av.oz. Mix and proceed as in No. I. Tonic Bath Salt. VI. Iron sulfate av.oz. Magnesium sulfate av.oz. Sodium sulfate av.oz. Salt av.oz. Mix and proceed as in No. I. PERFUMED AMMONIA WATER. This is a more or less diluted am- monia water which is perfumed and possibly colored; sometimes soap and alkalies are added. Sometimes it con- tains considerable alcohol in which case it is not strictly a "water." It is added to water used for bathing or washing to soften it. I. Palmer's formula : Ammonia water, 10% fl.oz. 8 Green soap av.oz. 4 Oleic acid dr. 2^2 Oil of bay m. 15 Oil of rosemary m. 15 Oil of verbena m. 75 Distilled water, to make fl.oz. z^ Dissolve the soap in a pint of water by the aid of heat, allow to cool, add the ammonia water and oils, mix by agitation, and then incorporate the acid and the remainder of the water. Oil of lemon grass of good quality may be substituted for the oil of ver- bena, BATH, FOOT AND MANICURE PREPARATIONS. 1019 II. Stronger ammonia water. . .fl.oz. II Soft (green) soap av.oz. 2 Borax av.oz. y 2 Cologne water fl.oz. 1 Distilled water, to make fl.oz. 24 Prepare like No. I. Lavender Ammonia. (Lavender Lo- tion.) Any of the preceding may be made into lavender ammonia water by using oil of lavender flowers as the per- fume. These preparations may be tinted a suitable color by means of solution of litmus. The following are also good formulas : III. Mme. Qui Vive's formula: Ammonia water fl.oz. 3 Alcohol fl.oz. 12 Oil of lavender flowers fl.dr 3 Color, if desired. IV. Ammonia water fl.oz. 8 Distilled water fl.oz. 7 Alcohol fl.oz. 1 Oil of lavender flowers drops 10 Color, if desired. If more alcohol is used, more oil may be incorporated with the mixture. Violet Ammonia. (Violet Lotion.) These are usually colored green with solution of chlorophyll or with the fol- lowing solution: Copper sulfate av.oz. 1 Potassium bichromate av.oz. 1 Ammonia water fl.oz. 8 Distilled water fl.oz. 16 V. Mme. Qui Vive's formula: Ammonia water fl.oz. 13 Alcohol fl.oz. 12 Essence of violets fl.dr. 3 VI. Stronger ammonia water. . .fl.oz. 7 Stronger tincture of orris, .fl.oz. 1 Alcohol fl.oz. 1 Distilled water fl.oz. 24 Chlorophyll, to color. Mix and filter .in a closely-covered funnel through talcum. FOOT PREPARATIONS. These consist of powders or liquids, usually the former. They are recom- mended for tender feet, frequently also for excessive perspiration of the feet. These two conditions often occur to- gether, though not necessarilv so, and sweatiness is usually accompanied by a bad odor, or bromidrosis (sweatiness being hyperidrosis). FOOT POWDERS. According to Picken's analysis of commercial foot powders, these usually contain powdered talcum and boric acid, sometimes zinc oxid, starch, orris root, salicylic acid, borax, and alum. The proportion of alum was found to be 3 to 20%, of salicylic acid, 3 to 7%, of zinc oxid, about 25%, and of starch, 15 to 65%. Foot powders therefore con- sist of talcum and boric acid to which may be added, or which may be par- tially replaced by, zinc oxid and starch ; antiseptics should be added, salicylic acid being especially good for sweaty, ill-smelling feet. Alum may be added for its astringent property. The mix- ture may be perfumed in any desired manner. All foot powders should be reduced to a very fine condition by continued trituration and oassing through a fine sieve. They are recommended for ten- der, tired, or sweaty feet, and if con- taining suitable antiseptics are also bene- ficial for bad-smelling feet. The pow- der is to be sprinkled into the shoes and socks. Frequent washing of the feet and daily changes of socks, are also to be recommended. These powders may be put up in nice round boxes or cartons and may be known by such names as "foot powder." "foot rest," "easy feet," "foot comfort," etc. I. Salicylated powder of talc, N. F., is an excellent foot powder, of the fol- lowing composition : Salicylic acid av.oz. 1 Boric acid av.oz. 3J6 Talcum av.oz. 29 Reduce all to fine powder, mix well and pass through a fine sieve. II, Salicylated Powder with Talc of 1020 THE STANDARD FORMULARY the German Pharmacopeia is like the preceding but contains wheat starch in- stead of boric acid. III. Sulfur av.oz. 2 Boric acid av.oz. 4 Talcum av.oz. 6 Prepare like No. I. IV. Alum av.oz. 1 Boric acid av.oz 2 av.oz. 4 av.oz. 6 Talcum , Starch , Oil of lavender -flowers. Prepare like No. I. drons 15 av.oz. 10 .av.oz. 2 .av.oz. 6 .av.oz. 12 .av.oz. 1 .av.oz. 1 .av.oz. 10 .av.oz. 12 ..fl.dr. 2 Orris root av.oz. 2 Zinc oxid av.oz. 2 Sulfur av.oz. 2 Talcum Prepare like No. I. VI. Orris root Zinc oxid Talcum Prepare like No. I. VII. Salicylic acid Zinc oleate Boric acid Talcum -Oil of eucalyptus.. Prepare like No. I. FOOT LOTIONS. Instead of foot powders, lotions may be recommended but they have not proven so popular. They are, however, useful adjuncts to the powders. For example it is advisable to bathe the feet every night in hot water contain- ing an antiseptic such as boric acid, po- tassium permanganate or sodium per- borate. The latter may be used as a 2% solution, potassium permanganate as a 1% solution, and boric acid in the saturated form. In case it is not possi- ble to change socks or stockings everv morning, the latter may be soaked at bedtime with the boric acid solution and hung up to dry over night. Other applications that may be used are these : I. Boric acid dr. t Borax dr. 2 Salicylic acid dr. 4 Glycerin fl.oz. 6 Alcohol fl.oz. 9 Perfume to suit Dissolve the boric acid and borax in the glycerin by the aid of heat, the sali- cylic acid in the alcohol, mix the two solutions, add any desired perfume, and filter. This may be applied to the feet night and morning. II. Formaldehyde fl.oz. 3 Tincture of nutgall fl.dr. 4 Cologne water fl.oz. 2 Diluted alcohol fl.oz. This is to be daubed on the feet with a pledget of cotton at night. ARM-PIT POWDER AND PASTE. Any of the foot powders may be used as an armpit powder to prevent perspiration and to overcome the odor. The following is specially adapted for this purpose: Salicylic acid gr. 45 Zinc oxid av.oz. 1 Orris root av.oz. 2 Talcum av.oz. 7 Cumarin gr. I Oil of bergamot drops 10 Oil of rose drops 20 Tincture of musk drops 5 Solution of carmine to color Reduce the solids to fine powder, mix thoroughly with the other ingredients, and pass through a fine sieve. The solu- tion of carmine may be omitted and the perfume changed. See Chapter II un- der face powders for nice perfume mix- tures for this purpose. Pastes for perspiration are the fol- lowing: I. Salicylic acid dr. 2 Corn starch av.oz. 13 Mucilage of tragacanth, to make a paste. II. Carbolic acid gr. 30 Burnt alum dr. 2 Talcum dr. 2 Orris root av.oz. 1 Corn starch av.oz. 10 Violet extract fl.dr. 2 Glycerin, to make a paste. BATH, FOOT AND MANICURE PREPARATIONS. 1021 MANICURE OR FINGER-NAIL COSMETICS. Cosmetic preparations intended for the finger-nails and finger-tips are now- used a great deal and this work would not be complete without formulas for these articles. They include cleaners, polishes, and varnishes. Nail Bleach and Wash. (Nail-Clean- ing Liquid) I. Oxalic acid dr. I Rose water fl.oz. 2 Apply to the discolored nails with friction by means of soft leather or flannel. Citric or acetic acid may be substi- tuted for the oxalic acid. II. Tartaric acid dr. I > Tincture of myrrh fl.dr. I * Cologne water fl.dr. 2 Distilled water, to make fl.oz. 3 Dissolve the acid in water, add the other ingredients, and strain. Dip the nails in this solution, wipe nearly dry, and polish with a chamois pad (buffer). III. Diluted sulfuric acid.. Tincture of myrrh Water, to make Use like the preceding. IV. Sodium perborate is highly rec- ommended as a nail bleach. Mix one teaspoonful with about i T/ - ounces of lukewarm water, and apply the liquid to the finger nails with a nail brush, rub- bing for a few minutes. The powder may also be sprinkled dry on the nails and then rubbed with a damp brush, but the first-mentioned method is the most satisfactory. Sodium perborate is to be preferred to hydrogen peroxid because its alka- line character enables it to dissolve the fatty matter of the nails and thus exert its bleaching agent, while the peroxid is always acid and has but little action on the nails. ...fl.dr. 4' ...fl.dr. 2 ...fl.oz. 2 Nail Ointment. White petrolatum av.oz. 4 White castile soap, powder. av.oz. % Oil of bergamot or other perfume sufficient This is used for softening the nails, curing hang-nails, etc. It is to be ap- plied at night, the fingers being covered with gloves. Nail Polishes. I. Different preparations of tin have been used successfully for cleansing and polishing finger nails, probably on ac- count of their detergent and astringent qualities. The use of tin oleate has been highly recommended for imparting a luster to the nails, and when colored with a little carmine, gives to them a roseate tint. The oleate is preoared as follows : To a solution of white cas- tile soap in warm water, 1 av. ounce to the pint, gradually add a 10% solution of tin chlorid until it ceases to pro- duce a precipitate. The insoluble sub- stance formed, after being washed and dried, is tin oleate. It is a soft solid, and is used without further preparation, unless, as stated, it be tinted with car- mine. It may be perfumed if desired. II. Another polish for finger nails is tin stearate. It is superior to the oleate, being stiffer and thus nicer to use. It may be prepared like the oleate by precipitation, using solutions of so- dium or potassium stearate and tin chlorid. This may be tinted with car- mine if desired. If a cheaper preoara- tion is wanted^ it can be mixed with equal parts of zinc oxid. III. Putty powder av.oz. 4 Carmine gr. 10 Oil of rose drops 3 Oil of neroli drops 3 Triturate the putty powder and car- mine together to a very fine powder, then incorporate with the oils. IV. Sodium perborate in nail pow- ders acts as a slow bleach and improves the luster, as in the following: 1022 THE STANDARD FORMULARY Puttv powder av.oz. 4 Sodium perborate dr. 2 Carmine gr. 30 Perfume to suit Prepare like the preceding. V Eosin gr. 40 White wax dr. 2 Spermaceti dr. 2 Paraffin wax av.oz. 4 Melt the waxes at a gentle heat and incorporate the eosin. The latter should be in very fine powder, or should be dissolved in a small amount of alcohol in which case the heat must be con- tinued till all the alcohol has evapor- ated. Nail Varnish or Enamel. Paraffin wax dr. 1 Chloroform fl.oz. 2 Oil of rose drops 3 Polish the nails in the usual manner, apply the varnish, and rub with chamois skin or buffer. ART V. SODA WATER PREPARATIONS. The following include the latest creations of the soda dispensers' art, and comprise those beverages which have been found most popular with the public, in recent years. Alhambra Cream. Prepare a syrup as follows > Peach syrup fl.oz. 2 Orange syrup fl.oz. 6 Vanilla syrup fl.oz. 9 Cream fl.oz. 7 In serving, draw about 1 ounce of this syrup into a 12-ounce glass, fill the glass half full with the coarse stream of carbonated water, and "finish" with the fine stream. Alhambra Syrup. Peach syrup fl.oz. 3 Orange syrup fl.oz. 8 Vanilla syrup fl.oz. 12 Cream, to make fl.oz. 32 Serve "solid" in 8-ounce glasses or with foam in 12-ounce glasses. Almond Chocolate. Almond essence fl.dr. 1 Chocolate syrup fl.oz. 32 Serve with cream or ice cream in 12- ounce glasses. Angel Food. Vanilla syrup fl.oz. 1 Red orange syrup fl.oz. 1 Ice cream oz. 2 Shaved or cracked ice soda glassful "%, Shake together in the usual manner, strain into a 12-ounce glass, nearly fill the latter with the coarse stream of carbonated water, and "finish" with the fine stream. Angostura Phosphate. Prepare a lemon phosphate in the usual manner, then add two dashes of angostura bitters. Ariom. Apricot syrup fl.oz. y 2 Peach syrup fl.oz. y 2 Rose syrup fl.oz. y 2 Cream fl.oz. 2 Shaved or cracked ice soda glassful y 2 Shake together the same as any other egg drink, strain into a 12-ounce glass, add the coarse stream of carbonated water to nearly fill the glass, and "fin- ish" with the fine stream of carbonated water. Arosia. Pineapple juice fl.oz. 2 l /> Plum extract fl.dr. l /i Quince extract fl.dr. J / 2 Solution of citric acid. .. .fl.dr. 1 Soda foam fl.dr. 2 Soda syrup fl.oz. ^ Yellow coloring, to color light yellow. Serve like other soda syrups, in 12- ounce glasses, with or without ice cream. Bimbo Flip. Strawberry syrup fl.oz. \ l / 2 Ginger syrup fl.oz. 1 Lime juice fl.oz. y± Egg 1 Prepare and serve like other egg drinks. Bisque Syrup. Roasted almonds av.oz. 4 Extract of vanilla fl.dr. ' \ Soda syrup fl.oz. t> 2 Break up the almonds to coarse pow- der, boil for a few minutes with about 8 ounces of the syrup, allow to cool, strain, and add the extract and the re- mainder of the syrup. This is to be served in 12-ounce glasses with or without ice cream. Blizzardine. Orgeat syrup fl.oz. t Catawba syrup fl.oz. \ 2 102- THE STANDARD FORMULARY Ice cream tablespoonful i Shaved of cracked ice soda glassful y 2 Shake together in a shaker, strain into a 12-ounce glass, nearly fill the glass with the coarse stream of car- bonated water, and "finish" with the fine stream. Bonnie Belle Cream. Pineapple syrup fl.oz. Y\ Vanilla syrup fl.oz. $£ Ice cream oz. 2 Egg 1 Shaved or cracked ice soda glassful y Shake in a shaker, or glass and shaker, strain into a 12-ounce glass, nearly fill the latter with the coarse stream of carbonated water, and "finish" with the fine stream. Brunswick Cooler. Lemon syrup fl.oz. y 2 Orange syrup fl.oz. y 2 Cherry syrup fl.oz. y 2 Shaved or cracked ice glassful % Add carbonated water, coarse stream, to nearly fill a 12-ounce glass, "finish" with the fine stream and dress the drink with pineapple and cherry fruit. Caramel Syrup. Extract of coffee fl.dr. i]/ 2 Extract of vanilla fl.dr. y> Caramel fl.dr. 1 Chocolate syrup fl.oz. 8 Soda syrup, to make fl.oz. 32 Serve in 12-ounce glasses with or without ice cream. Carnation Flip. Pineapple syrup fl.oz. f Strawberry (or raspberry) syrup fl.oz. 1 Cream fl.oz. 4 Ice cream spoonful 1 Egg 1 Shaved or cracked ice soda glassful y Shake in a shaker, or glass and shaker, strain into a 12-ounce glass, fill the latter with the coarse stream of car- bonated water and sprinkle on some powdered nutmeg. Carnation Float. Make a plain lemonade in the usual manner, fill the glass to within an inch of the top, then in the center of the glass hold the spoon upright, and down the side of the latter slowly pour in grape juice until the p^lass is full. Catawba Frappe. Catawba syrup fl.oz. 2 Orange syrup fl.oz. l / 2 Draw into a 12-ounce glass, add shaved ice to half fill the glass, add water to nearly fill the latter, then fill with carbonated water, stir with a spoon and serve with straws. Cherry Egg Bounce, Hot. Egg 1 Cherry juice fl.oz. 2 Sugar, powder spoonful 1 Mix thoroughly in an 8-ounce mug, fill up the latter with hot water, mix again, add several cherries, a slice of orange, and a sprinkle of nutmeg. Chinese Punch. Shaved or cracked ice soda glassful l /t Tea syrup fl.oz. 2 Carbonated water, coarse stream, to fill the glass. Stir with a spoon and serve with straws. Chocolate Frappe. Chocolate syrup fl.oz. 1 y 2 Ice cream oz. 2 Cream fl.oz. 2 Mix thoroughly in a 12-ounce glass, nearly fill the latter with the coarse stream of carbonated water, and "finish" with the fine stream. Chocolate Nectar. Vanilla extract fl.dr. l / 2 Orange flower water fl.dr. 4 Chocolate syrup, to make ... fl.oz. 32 Carmine solution to color reddish- brown. Draw 2 ounces of this into an 8-ounce glass, add one ounce of cream, and fill the glass with the coarse stream of carbonated water. Chocolate Punch. Chocolate syrup fl.oz. 2 Egg 1 Shaved or cracked ice soda glassful y Milk, enough to fill a 12-ounce glass. Shake together, strain into a 12-ounce SODA WATER PREPARATIONS. 1025 glass, fill the latter with the fine stream of carbonated water, and add some whipped cream. Claret Glace (Claret Klondike.) Fill a sherbet glass with finely shaved ice, pour on an ounce of claret syrup, and garnish with a thin slice of lemon. Serve with a sherbet spoon. Claro. Juice of lemons 3 Strawberry juice " fl.oz. 4 Raspberry juice fl.dr. 4 Solution of citr' acid fl.dr. 6 Soda foam fl.dr. 4 Soda syrup fl.oz. 48 Serve like other soda syrups with or without ice cream, in 12-ounce glasses. Coffee Maltrose. Coffee syrup fl.oz. 1 y 2 Egg 1 Malted milk teaspoonful 1 Cream fl.oz. \Y 2 Cracked or shaved ice soda glassful l / 2 Shake together, strain into a 12-ounce glass, nearly fill the latter with the coarse stream of carbonated water, and "finish" with the fine stream. Coney Fizz Orange syrup fl.oz. 1 Strawberry syrup fl.oz. 1 Juice of one-half lemon. Shaved or cracked ice soda glassful x /\ Shake together in a shaker, strain into a 12-ounce glass, nearly fill the glass with the coarse stream of car- bonated water, "finish" with the fine stream, and decorate with fruit. Creme-de-Swift. Vanilla syrup fl.oz. y 2 Strawberry syrup fl.oz. 1 Cracked or shaved ice glassful T /i Milk, enough to fill a 12-ounce glass. Shake well, strain, and top with whipped cream. Cream Cordial. Rose syrup • fl.oz. l / 2 Pineapple syrup fl.oz. l / 2 Vanilla syrup fl.oz. Y> Orange syrup fl.oz. l / 2 Cream fl.oz. 1 Shaved or cracked ice soda glassful T 4 Shake in a shaker, strain into a 12- ounce glass, nearly fill the glass with the coarse stream of carbonated water, and "finish" with the fine stream. Cream Pineapple. Crushed pineapple fl.oz. i~y 2 Cream fl.oz. 2 Crushed or shaved ice glassful % Shake together, strain into a 12-ounce glass, add carbonated water, coarse stream, to nearly fill the latter, and "finish" with the fine stream. Crescent Sherbet. Pineapple syrup fl.oz. 16 Orange syrup fl.oz. 16 Vanilla syrup fl.oz. 12 Sherry wine fl.oz. 4 Serve as a "solid" drink in 8-ounce glasses, using 1 or i z / 2 ounces of this syrup and filling the glass with the coarse stream of carbonated water. Cubanade. Orange syrup fl.oz. 1 Grape juice fl.oz. l / 2 Lemon juice fl.dr. 1 Essence of ginger a few drops Put into a 12-ounce glass, nearly fill the latter with the coarse stream of carbonated water, and "finish" with the fine stream. Egg-a-la-Mode. fl.oz. Peach syrup Pineapple syrup. . , . . fl.oz. ]/ 2 Lemon syrup fl.oz. ]/ 2 Egg 1 Shaved or cracked ice soda glassful % Shake in a shaker, or glass and shaker, strain into a 12-ounce, nearly fill the glass with the coarse stream of carbonated water, and "finish" with the fine stream. Egg Cocoa. Chocolate syrup fl.oz. 1 White and yolk of egg 1 Cracked or shaved ice. small quantity Shake well in a shaker, or glass and shaker, strain into 12-ounce glass, nearly fill the latter with the coarse stream of carbonated water, and "finish" with the fine stream. 1026 THE STANDARD FORMULARY Egg Soda. Lemon syrup fl.oz. Vanilla syrup.. ..fl.oz. Cream fl.oz. i Egg i Shaved or cracked ice about tablespoonful i Shake in a shaker or a glass and shaker, strain into a 12-ounce glass, nil the latter three-fourths with the coarse stream of carbonated water, and "finish" with the fine stream. Elks' Delight. Juice of one-half orange. Juice of one-half lemon. Grape juice fl.oz. Yz Sugar, powder teaspoonful 2 Shaved or cracked ice soda glassful Y> Plain water, enough to fill a 12-ounce glass. Strain, add a cherry and a slice of orange, and serve with straws. Fancy Lemonade. Make a soda lemonade in the usual manner, and add a teaspoonful of rasp- berry or strawberry syrup, which will sink to the bottom of the liquid. Then carefuly pour in a teaspoonful of grape juice, and serve without stirring. A piece of pineapple, orange or other fruit may be added to decorate the drink. It may also be served in a glass half- full of shaved ice. Serve with straws. Fantasma Nog. Wild cherry syrup fl.oz. iV 2 Egg 1 Ice cream spoonful 1 Solution of acid phosphate. dashes 2 Shaved or cracked ice soda glassful *4 Favorita. Strawberry juice fl.oz. 4 Maple syrup fl.oz. t6 Juice of 6 lemons. Soda foam fl.oz. 1 Soda syrup, to make gal. ]/ 2 Serve like other soda syrups in 12- ounce glasses with or without ice cream. Frosted Chocolate. Chocolate syrup fl.oz. i l / 2 Shaved ice glassful l / 2 Carbonated water, coarse stream, about fl.oz. 6 Mix by stirring, strain into a 12-punce glass, and filter the latter with the line stream of carbonated water. Frosted Coffee. Coffee syrup fl.oz. 2 Cream fl.oz. 2 Shaved or cracked ice soda glassful l / 2 Shake thoroughly in a combination shaker or in a glass and shaker, strain into a 12-ounce glass, fill the glass with the coarse stream of carbonated water, stir thoroughly, add a spoonful of whipped cream, and sprinkle lightly with nutmeg. Ice cream may be used instead of whipped cream. Frozen Cream. Banana syrup fl.oz. 2 Cream fl.oz. 8 Shaved or cracked ice soda glassful l / 2 Shake together in a shaker, strain into a 12-ounce glass, add a few pieces of banana, fill the glass with the fine stream of carbonated water, and serve with a spoon and straws. Fruit Lemonade. Crushed ice glassful 1 Sugar, powdered. . .tablespoonfuls 2 Juice of one-half lemon. Juice of one-half orange. Lemon slice 1 Orange slice 1 Pineapple slice l / 2 Orange flower water drops 2 Prepare and serve like plain lemon- ade. Fruit Malt. Malt extract, thick fl.oz. 6 Raspberry syrup fl.oz. 2 Cinnamon syrup fl.oz. 2 Rose syrup fl.oz. 2 Orange flower water fl.dr. 2 Orange syrup fl.oz. 12 This may be served as a "soda" drink with foam in 12-ounce glasses or "solid" in 8-ounce glasses or as a "phosphate." Fruit Nectar. Raspberry syrup fl.oz. 16 Grape syrup fl.oz. 16 Raspberry vinegar fl.oz. 2 Serve this as a "solid" drink in 8- ounce glasses, adding shaved ice if de- sired. SODA WATER PREPARATIONS. 1027 Fruit Shrub. Pineapple juice fl.oz. I Grape juice fl.oz. I Raspberry juice fl.oz. I Extract of vanilla fl.dr. y 2 Solution of citric acid fl.dr. 2 Soda syrup, enough to make fl.oz. 32 Serve like other soda syrups in 12- ounce glasses, with or without ice cream. Ginger Bouquet. Soluble essence of ginger. . .fl.dr. 10 Solution of citric acid fl.dr. 4 Essence of sarsaparilla fl.dr. 4 Extract of vanilla fl.dr. 4 Soda syrup, to make fl.oz. 32 Caramel enough to color Serve this as a "solid" drink in 8- ounce glasses. Shaved ice may be added. Ginger Wine Toddy, Hot. Ginger syrup fl.oz. y 2 Tea syrup fl.oz. 1 Currant juice ...fl.oz. y 2 Draw into an 8-ounce mug, fill the latter with hot water, and add grated cinnamon. Golden Buck. Yolk of egg 1 Orange syrup fl.oz. 2 Solution of acid phosphates . dashes 2 Shaved or cracked ice soda glassful 54 Shake together in a shaker, or in a glass andT shaker, strain into a 12-ounce glass, nearly fill the glass with the coarse stream of carbonated water, and "finish" with the fine stream. Granola. Orange syrup fl.oz. 1 Grape juice fl.oz. y 2 Juice of one-half lemon. Cracked or shaved ice soda glassful 3/3 Mix in a 12-ounce glass, nearly fill the latter with the coarse stream of carbonated water, and "finish" with the fine stream. Serve with straws. Grape-Ade. Lemon syrup fl.oz. 1 Grape juice fl.oz. l / 2 Serve "solid" in 8-ounce glasses, fill- ing the latter with the coarse stream of carbonated water, and stirring with a spoon. 65 Grape Cooler. Grape juice. . . . fl.oz. Orange syrup fl.oz. i*/ 2 Lemon syrup fl.oz *4 Solution of acid phosphate, .dash 1 Shaved or cracked ice soda glassful y± Mix in a 12-ounce glass, fill the lat- ter with the coarse stream of carbon- ated water, stir with a spoon, add a slice of pineapple, and serve with straws. Grspe Cup. Grape juice fl.oz. 32 Infusion of tea fl.oz. 32 Lime juice fl.oz. 8 Solution of acid phosphate, .fl.oz. 1 Keep cool with ice, serve in glasses three-fourths full, and fill with the coarse stream carbonated water. By infusion of tea is meant "tea" as it is made for household purposes, preferably using a good grade of tea v like English breakfast, pekoe, souchong, etc. Grape Egg Phosphate. Make an egg phosphate in the usual manner and add a tablespoonful of grape juice before serving. Grape Glace. Grape juice fl.oz. 8 Water fl.oz. 8 Whites of 1 or 2 eggs. Sugar, powder av.oz. 16 Beat the egg-white with some of the sugar, then add the mixed juice, water, and the remainder of the sugar. Keep in a small pitcher or berry dish. Serve with~a spoon. This must be made fresh every day. Grape Lemonade. Grape syrup fl.oz. V 2 Lemon syrup fl.oz. : i Solution of acid phosphates. dash 1 Serve as a "solid" drink with the coarse stream of carbonated water. Grape Orange. Prepare like the preceding, substitut- ing orange syrup for the lemon syrup. Grape Sherbet. Orange syrup fl.oz. 2 Grape juice fl.oz. 2 Draw into a 12-ounce glass, half fill 1028 THE STANDARD FORMULARY the latter with shaved ice, then fill it with plain water, stir with a spoon, and serve with straws. Hasty Pudding. Crushed strawberries oz. x / 2 Crushed peaches oz. l / 2 Ice cream, to fill a small glass or sherbet cup. Serve with a spoon. Heavenly Twins. Ice cream spoonful I Lemon ice . spoonful i Put side by side on a decorated plate, place over it some crushed fruit, and serve with wafers. Herculine. Spirit of orange fl.oz. I Tincture of vanilla fl.oz. i Tincture of citrochlorid of iron fl.oz. I Solution of acid phosphate, .fl.oz. 2 Caramel, enough to color light brown. This is a tonic syrup, one ounce of which is to be served with carbonated water as a "solid" drink in 8-ounce glasses. Hokey-Pokey Glace. Nectar syrup fl.oz. 1 Carbonated water fine stream soda glassful Y\ Finely shaved ice, enough to fill the glass. Add some whipped cream and serve with a spoon. Ice Cream Sandwiches. These are made by spreading a thin layer of ice cream between two sugared vanilla wafers. Another way of preparing them is to have thin cakes like vanilla wafers of the size of the brick ice cream moulds, spread on them thin layers of raspberry or apricot jam, cut brick ice cream into slices, lay a slice between the layers of cake, and place the whole in the ice cream cabinet until needed. Ice Cream Shake. Marshmallow syrup fl.oz. 1 Egg 1 Ice cream oz. 1 Shake together in a shaker, or glass and shaker, strain into a 12-ounce glass, nearly fill the latter with the coarse stream of carbonated water, and "finish" with the fine stream. Idlewild. Strawberry syrup fl.oz. 10 Orange syrup fl.oz. 10 Pineapple syrup fl.oz. 10 Lemon juice fl.oz. 2 Draw \ x / 2 ounces of this into a 12- ounce glass one-third filled with shaved ice, then fill the glass with the coarse stream of carbonated water, add a few strawberries, a slice of pineapple and a slice of orange, and serve with straws. Independence Tonic. Coffee syrup fl.oz. 8 Elixir of coca fl.oz. 4 Tincture of_ cinchona fl.oz. 2 Madeira wine fl.oz. 2 Raspberry syrup fl.oz. 16 Serve "solid" in 8-ounce glasses, drawing 1 or i l / 2 ounces of this syrup and filling the glass with the coarse stream of carbonated water. Kola Celery Tonic. Fluid extract of kola fl.dr. 1 Tincture of celery seed fl.dr. 4 Solution of citric acid fl.dr. 3 Raspberry juice fl.oz. 1 Soda syrup, to make fl.oz. 32 Serve "solid" in 8-ounce glasses, using about 1 ounce of this syrup. Kola Syrup. Fluid extract of kola (from fresh nuts) fl.dr. 2 Claret wine fl.oz. 12 Raspberry juice fl.oz. V/2 Solution of acid phosphates. fl.oz. 4 Solution of citric acid fl.oz. 2 Soda syrup, to make gall. */> Solution of carmine, to color deep red. Serve "solid" in 8-ounce glasses, us- ing about 1 ounce of this syrup and fill- ing the glass with the coarse stream of carbonated water. Kolasaya. Blood orange syrup fl.oz. 16 Raspberry syrup fl.oz. 8 Wine of kola fl.oz. 4 Elixir of calisaya fl.oz. 4 Mix well and filter. In serving, draw 2 ounces of this SODA WATER PREPARATIONS. 1029 syrup in a 12-ounce glass, add cracked or shaved ice, and fill with the coarse stream of carbonated water. Top off with same fresh raspberries or a piece of orange. Ladies' Choice. Raspberry syrup fl.oz. 2 Peach ice cream. . .tablespoonfuls 2 Serve in 12-ounce glasses like any "soda" drink with the coarse and fine streams of carbonated water. Lime Juice Fizz, Hot. White of egg 1 Lime juice fl.oz. 1 Sugar, powder spoonfuls 2 , Mix in an 8-ounce -mug, fill the latter with hot water, and add some whipped cream. Lime Slip. Pineapple syrup fl.oz. 2 Lime juice fl.oz. y 2 Serve "solid" in 8-ounce glasses, add- ing a slice of orange. Manhattan Cream. Pineapple syrup fl.oz. 24 Vanilla syrup fl.oz. 24 Ice cream oz. 2 Egg 1 Shaved or cracked Shake in a shaker or glass and shaker, strain into a 12-ounce glass, nearly fill the latter with the coarse stream of car- bonated water, and "finish" with the fine stream. Oriental Fizz. Strawberry syrup fl.oz. 1 Orange syrup fl.oz. 1 Juice of one-half lemon. Shaved or cracked ice soda glassful % Mix in a 12-ounce glass, fill the latter with the coarse stream of carbonated water, stir with a spoon, and serve with straws. Over the Waves. Lemon syrup fl.oz. i l / 2 Grape juice fl.oz. 1 White of one egg. Solution of acid phosphates. fl.dr. l / 2 Cracked or shaved ice soda glassful J /i Shake in a shaker or glass and shaker, strain into a 12-ounce glass, nearly fill the latter with the coarse stream of car- bonated water, and "finish" with the fine stream. Orange Chocolate. Extract of vanilla fl.dr. 2 Orange-flower water fl.dr. 4 Chocolate syrup, to make... fl.oz. 32 This may be served with cream or ice cream in 12-ounce glasses. Orange Ferrone. Orange syrup fl.oz. 16 Raspberry syrup fl.oz. 8 Vanilla syrup fl.oz. 4 Elixir gentian with iron. .. .fl.oz. 4 Serve "solid" in 8-ounce glasses, us- ing 1^ or 2 ounces of this syrup. Orange Mint. Half fill a 12-ounce glass with crack- ed ice, draw in 2 T A ounces of orange syrup, fill with the coarse stream of car- bonated water, add a dash of essence of peppermint and a slice of orange, stir with a spoon, and serve with a straw. Pan-American Lemonade. Orange syrup fl.oz. 1 Lemon syrup fl.oz. 1 Sugar, powdered teaspoonful 1 Solution of acid phosphate. . .dash 1 Shaved or cracked ice soda glassful V3 Fill the glass with the coarse stream of carbonated water, add two slices of orange, and serve with two straws. Pepsin Phosphate. Glycerite of pepsin, N. F... fl.oz. 4 Raspberry syrup fl.oz. 8 Solution of acid phosphate, .fl.oz. 2 Soda syrup, to make fl.oz. 32 Serve "solid" in 8-ounce glasses, like other phosphates. Phantom Bouquet. Vanilla syrup fl.oz. 4 Pineapple syrup fl.oz. 8 Orange syrup fl.oz. 12 Orange-flower water fl.oz. 1 Serve in 8 or 12-ounce glasses with cream. Pierian Spring Syrup. Take one orange, cut into cubes, leav- ing the peel on; one peach, remove the peel and stone and crush the meat ; one banana, remove the peel, and cut the 1030 THE STANDARD FORMULARY inner part into cubes; one-half pine- apple, remove the peel and grate the meat ; one dozen strawberries, remove the calyces and crush ; mix all with a half-gallon of soda syrup, previously colored red. To serve, put ice cream in the bottom of a glass, add about an ounce of this syrup, and nil the glass with the fine stream or carbonated water. Pineapple Ale. Soluble essence of ginger. . .fl.oz. 2 Pineapple juice fl.oz. 2 Solution of citric acid fl.dr. 2 Soda syrup fl.oz. 24 Serve "solid" in 8-ounce glasses like the "phosphates." Pineapple Bonbon. Fill a sherbet glass nearly full with crushed pineapple, place a spoonful of finely shaved ice, add a ladleful of crushed pineapple, place a spoonful of ice cream on top of all, and serve with a sherbet spoon. A similar "bonbon" may be made with any other kind of crushed fruit. Pineapple Frappe. Cracked or shaved ice soda glassful y 2 Crushed pineapple fl.oz. 2 Solution of acid phosphates. fl.dr. 1 Mix in a 12-ounce glass, fill the glass with carbonated water, stir with a spoon, and strain into an 8-ounce glass. Pineapple Lemonade. Juice of one lemon. Pineapple syrup fl.oz. 2 Carbonated water, to fill a 12- ounce glass. Mix well, dress with fruit, and serve with straws. Pineapple Paulette. Pineapple syrup fl.oz. \ l / 2 Tee cream oz. 2 Cream fl.oz. V/ 2 Cracked or shaved ice soda glassful % Shake together in a shaker, strain into a 12-ounce glass, add carbonated water, coarse stream, to nearly fill the glass, and "finish" with the fine stream. Pineapple Punch. Pineapple juice fl.oz. 2 Sugar, powdered spoonful 1 Shaved ice, soda glassful Y3 Mix with a spoon, add 3 ounces of the coarse stream of carbonated water, add a little more shaved ice and a spoonful of crushed pineapple on top. Fill the glass with shaved ice, add a slice of pineapple, and serve with a spoon and straws. Pineapple Snow. Pineapple syrup fl.oz. 1 Sugar, powder teaspoonful 1 Cracked or shaved ice soda glassful y 2 Add some carbonated water, stirr in a shaker, strain into an 8-ounce glass, fill the latter with the coarse stream of carbonated water, stir again, add a slice of pineapple or some crushed pineapple, and serve with straws. Another article of the same name is a mixture of cracked or shaved ice, cream and pineapple syrup, with or without carbonated water, the whole being top- ped off with shaved ice and dispensed in a glass with a spoon. Pink-Ade. Cranberry syrup fl.oz. 16 Juice of 1^ lemons. Solution of citric acid fl.dr. x / 2 Solution of acid phosphates. fl.dr. 2 Soda syrup fl.oz. 32 If necessary add cochineal coloring to impart a pinkish tint to the mixture. Serve "solid" in 8-ounce glasses like the "phosphates." Pink Tea, Hot. Green tea av.oz. 1 Black tea av.oz. 1 Water fl.oz. 16 Sugar av.oz. 10 Make an infusion of the two teas with the water, strain in the liquid, dis- solve the sugar, strain again, and color the liquid with tincture of cudbear. In serving, put 1 ounce into an 8- ounce mug, fill the latter with hot wa- ter, and add a slice of lemon. SODA WATER PREPARATIONS. 1031 Raspberry Royal. Raspberry syrup fl.oz. i l /> Raspberry vinegar fl.oz. ]/ 2 Cracked or shaved ice soda glassful }£ Mix in a 12-ounce glass, nearly fill the latter with the coarse stream of carbinated water, and "finish" with the fine stream. Serve with straws. Raspho. Raspberry syrup fl.oz. ^4 Orange syrup fl.oz. 1% Tincture of ginger dash 1 Solution of acid phosphates, .dash 1 Mix in 12-ounce glasses, using some shaved ice and the coarse stream of car- bonated water. Serve with straws. Root Bear, Hot. Mix one fluidounce of root beer ex- tract with 7 fluidounces of soda syrup. Use i x / 2 fluidounces of this syrup to enough hot water to fill an 8-ounce mug. Add a slice of lemon or a few drops of lemon juice. Root Beer Cream. Fill a 12-ounce glass to within one inch of the top with root beer drawn "solid," then float on enough plain cream to fill the glass. Serve without straws. Samaritan Punch. White and yolk of egg 1 Cracked or shaved Nectar syrup fl.oz. 2 Milk soda glassful }i Agitate in a shaker or in a glass and shaker, strain into a 12-ounce glass, and add some grated nutmeg. Snow Top. Orgeat syrup .fl.oz. 1 Cream fl.oz. 2 White of egg 1 Shaved or cracked ice sufficient Prepare like other egg drinks. Square Meal. Chocolate syrup fl.oz. 2 Egg 1 Ice cream spoonful 1 Milk enough to fill a shaker Shake well, strain into a 12-ounce glass, and sprinkle on some grated nut- meg. Strawberry Cream Puff. Put a large spoonful of ice cream in a glass, over it pour a ladleful of crushed strawberries. In another glass mix the contents of 1 egg, 1 ounce of straw- berry syrup, and 1 ounce of plain cream, and add this to the mixture in the other glass. Serve with a spoon. College Ice (Fruited Cream.) This is simply a sundae served with crushed fruit. Cantelope Sundae. Cut a small-sized canteloupe in two, remove the seeds, and slice off a small portion from the bottom so that the half-sections will stand upright. Place in the half of the canteloupe the usual or desired amount of ice cream, on the latter put some crushed pineapple and whole cherries. Insert spoon upright in meat of canteloupe, place the latter upon a napkin and serve upon a fancy plate. Sweet Clover. Tea svrup fl.oz. 8 Maple syrup fl.oz. 4 Solution of acid phosphates.fi. dr. 2 Soda syrup fl.oz. 24 Color green with any suitable green color. Serve "solid" in 8-ounce glasses like the "phosphates." Turkish Punch, Hot. Yolk of egg 1 Grape juice fl.oz. 1 Lemon juice fl.oz. l / 2 Sugar, powder spoonfuls 2 Mix thoroughly in an 8-ounce mug. fill the latter with hot water, stir again. top off with whipped cream and sprinkle on some cinnamon. Turkish Sherbet. Crushed peach fl.oz. l / 2 Nectar syrup fl.oz. l / 2 Orange syrup fl.oz. 1 2 Solution of acid phos- phates dashes 4 or 5 Fill a 12-ounce glass with shaved ice. stir in the above sirupy mixture, garnish with a slice of pineapple and orange and a cherry, and serve with spoon and straws. 1032 THE STANDARD FORMULARY Tutti Fruitti. Spirit of lemon fl.dr. I Spirit of orange fl.dr. I Tincture of vanilla fl.dr. i Maple syrup fl.oz. i Solution of citric acid fl.dr. 4 Soda syrup, to make fl.oz. 32 Serve with other soda syrups in 12- ounce glasses with or without ice cream. Vanilla Puff, Hot. Vanilla syrup fl.oz. 1 Cream fl.oz. 1 White of one egg. Shake well, strain in an 8-ounce mug, fill latter with hot water, and add whip- ped cream. Violade. Violet syrup fl.oz. 1 Lemon syrup fl.oz. 1 Carbonated water fl.oz. 8 Stir with a spoon, pour into another glass half filled with shaved ice, add two slices each of lemon and orange, and serve with straws. Wild Cherry Syrup. Oil of bitter almonds drops 6 Alcohol fl.dr. 4 Red cherry juice fl.oz. 8 Syrup of wild cherry, U. S. P fl.oz. 8 Diluted phosphoric acid fl.dr. 4 Tincture of cudbear fl.dr. 4 Caramel dr. 1 Soda syrup, to make gall. y 2 Dissolve the oil in the alcohol and add the other ingredients. Yabarra Chocolate. Orange syrup fl.oz. y 2 Chocolate syrup fl.oz. 1 Cream fl.oz. 2 Shaved or cracked ice soda glassful ^ Fill the glass with milk, shake and strain. ART VI DOMESTIC UTILITIES. ACID-PROOF COATING. The following recipes have been used in the preparations of coatings for acid tanks: (i) Asbestos powder, 2 parts; barium sulfate, 1 part; silicate of so- dium solution (50 B.), 2 parts. This is resistant to the strongest acids. For weak acids use the silicate at 30 B. (2) Silicate of sodium solution, 2 parts; sand, 1 part ; asbestos powder, 1 part. This is better than the first recipe when hot nitric acid has to be tanked. Either of these preparations will resist the ac- tion of sulfuric and nitric acids. ADHESIVES. See under headings Cements; Glues, Liquid; Mucilages; and Pastes. ALCOHOL, DENATURED. See Denatured Alcohol. ALLOYS of Low Melting Point. I. Newton's metal: Bismuth parts 8 Lead parts 5 Tin : . .parts 3 This mixture melts at 95 C. II. Rose's metal : Bismuth parts 2 Lead part 1 Tin ^..part 1 This mixture liquefies at 94° C. III. Wood's metal : Bismuth parts 15 Lead parts 8 Tin parts 4 Cadmium „. parts 3 This mixture melts at 68° C. AMMONIA, Household or Domestic. This is a combination of ammonia water with borax or other alkali, some- times with oleic acid or soap, the object being to fortify the ammonia or to make it less volatile. If the ammonia be combined with oleic acid and hard wa- ter, a cloudy preparation is obtained. The preparation may be perfumed, if intended for toilet purposes, with suita- ble essential oils or with a handkerchief extract. If not perfumed it is suitable for detergent purposes. I. Borax av.oz. 1 Oil of cinnamon drops 20 Oil of clove drops 20 Oil of citronella drops 20 Alcohol fl.oz. 2 Ammonia water gall. 1 Dissolve the borax in the ammonia and the oils in the alcohol, and mix the two solutions. II. Stronger ammonia water ... fl.oz. 40 Oleic acid fl.oz. 8 Alcohol fl.oz. 8 Distilled water, to make gall. 1 Mix all together and shake well. 1 or 2 ounces of borax may be added, also some oil of lavender flowers or hand- kerchief extract. If a cloudy prepara- tion is desired, replace a portion of the distilled water with hydrant water, the proportion required depending on the amount of solids in the water. III. Castile or soft soap av.oz. 8 Borax av.oz. 4 Stronger ammonia water. . .fl.oz. 32 Cologne water fl.oz. 4 Water, .to make gall. 1 Mix all and dissolve the solids. This makes a cloudy preparation. The co- logne water may be omitted, and if dis- tilled water be used a clear liquid will then n be obtained. ANT EXTERMINATORS AND EX- PELLERS. As far as is known at the present time, ants do no harm directly but have the disagreeable habit of "getting into things," such as in the sugar, syrups, 1034 THE STANDARD FORMULARY sweets, etc., in pantries or on bread ; in drug stores they occur commonly around the soda fountain. Gum camphor, which may be in the form of pieces, laid about in different parts of the pantry or refrigerator will expel ants but all articles of food will be spoilt from absorption of the odor of the camphor. The articles of food might be temporarily removed. Another sub- stance which has proved to be a success- ful ant exterminator is powdered borax, which is to be scattered freely on the pantry and refrigerator shelves and floor ; it should also be blown or thrown into all crevices and corners. Mustard, sulfur, alum and oil of cedar are also said to drive ants away, but the oil, like camphor, would be objectionable on account of its odor. Ants are said to be partial to lard and a tray smeared with it will entangle many of them. Chloroform or gasoline sprayed into crevices or corners, or into their nests if found, will destroy them. Gasoline must be used with caution, ow- ing to its inflammability, and therefore chloroform should be preferred. A sponge moistened with weak syrup will entangle many ants which may then be killed by dipping the sponge in hot water. Tartar emetic has also been recom- mended, used in a similar manner to borax. Balsam of peru is said to have been successful ; it is to be smeared into all crevices, and on different places on the shelves and across their pathways. It has also been suggested to boil peru balsam with water, about one ounce to the gallon, and to wash the shelves and floor with this liquid while hot. Alum in hot solution may also be used in the same manner. Ants at the soda fountain may be ex- pelled by the same means as outlined above, strewing powdered borax about, smearing peru balsam into crevices, or washing shelves or other parts made of wood with the hot balsam water. An experienced pharmacist claims to have had excellent results in driving ants from the fountain by making a mixture of equal parts of tartar emetic and sugar into a thick paste with glyce- rin and distributing small particles of this where they can get at it. Ants in the lawn, garden or field are easily destroyed by digging a sharp stick into the center of the hill and pouring into it from I to 4 ounces of carbon disulfid, then pressing the soil together again. The best time to destroy ants is immediately after a rain when the ground is cool and damp and there is less rapid absorption and volatilization of the sulfid. Chloroform will probably serve as well as carbon disulfid but would be objected to an account of its expensiveness if it has to be used exten- sively. A patented ant and gopher extermina- tor (patented in 1880) is directed to be made as follows : Alkanet root oz. 2 Arsenous acid oz. 2 Gum camphor oz. 4 Iodin oz. 1 Phosphorus oz. 2 Sulfur __ oz. 4 Carbon disulfid, to make gal. 1 Pour some of this liquid, about 3 or 4 ounces, into the holes, set fire to the vapor, and after a moment cover the opening with the surrounding dirt. ANTIDOTES TO POISONS. The following are the poison antidotes approved by the California Board of Pharmacy : Acid, Arsenous. — Emetic of mustard, hy- drated oxid of iron a cupful, follow with olive oil or white of egg. muci- laginous drinks. Laudanum (20 drops) if much pain. Acid, Carbolic. — Dilute alcohol or whisky and albuminous substances, milk, white of egg, etc. Acid, Hydrocyanic. — Cold water to head and spine. Give stimulants. Inhalation of ammonia. Artificial respiration. Acid, Muriatic; Acid, Nitric; Acid, Nitro- Muriatic; Acid, Sulphuric. — Give no emetics. Give at once large draughts and water or milk. Soft soap or soap and water, or white of egg beaten up with water, or give olive oil. Acid, Oxalic. — Give chalk or whiting (a tablespoonful) or plaster off the wall suspended in water. Emetic of mus- tard, large draughts of warm water, DOMESTIC UTILITIES. 1035 olive oil, mucilaginous drinks, stimu- lants (whisky, etc.). Apply warmth to the extremities. Aconite, Its preparations or derivatives. — Emetic of mustard followed by large draughts of warm water, then strong tea or coffee, or whisky. Keep patient in horizontal position. Keep up arti- ficial respiration. Antimony, and Its preparations. — (Tartar emetic) — Give emetics of mustard or zinc sulfate. Milk, white of egg freely mixed with water. Demulcent drinks. Antiseptic Tablets (Cor. Sub.).— See Cor- rosive Sublimate. Arsenic. — See Acid Arsenous. Belladonna, Its preparations or deriva- tives. — Emetic of mustard followed by large draughts of warm water, then strong tea or coffee. Bromin. — Arouse patient and keep him in motion. If inhalation: Fresh air, inhalation of ammonia. If swallowed: Emetic, starch, followed by magnesia, sodium bicar- bonate, white -of egg, milk, flour and water. Cantharides. — Avoid oils. Emetics first of all. Demulcents, stimulants. Em- ploy artificial heat externally. Chloral Hydrate. — Same as Chloroform. Chloroform. — Horizontal position, cold wa- ter to head and stimulants. Emetic of mustard. Cocculus Indlcus. — Same as Aconite. Conium. — Same as Belladonna. Corrosive Sublimate. — Give white of egg or flour mixed with water, emetic of mustard. Give strong tea or coffee, stimulants (whisky, etc.). If needed, demulcent drinks. Corrosive Sublimate Tablets. — Same as Corrosive Sublimate. Cotton Root and Its Preparations. — Emetic of mustard followed with large draughts of warm water, strong tea or coffee, stimulants (whisky, etc.) freely. Keep patient in horizontal position, em- ploy warmth to extremities, artificial respiration. Cowhage. — Large doses of olive oil. Creosote. — Emetic of mustard, white of egg beaten up with water, olive oil, magnesia, stimulants (whisky, etc.) freely, employ warmth and friction to the extremities. Croton Oil. — Give white of egg or flour mixed with water, emetic of mustard. Give strong tea or coffee, stimulants (whisky, etc.). If needed, demulcent drinks. Cyanid of Potassium. — Cold water to head and spine. Give stimulants. Inhalation of ammonia. Artificial respiration. Digitalis, Its preparations or derivatives. — Emetics of mustard followed with large draughts of warm water, strong tea or coffee, stimulants (whisky, etc.) freely. Keep patient in horizontal posi- tion, apply warmth to extremities, arti- ficial respiration. Ether. — Horizontal position, cold water to head and stimulants. Emetic of mus- tard. Formaline, or Solution of Formaldehyde. — Give ammonia in diluted solution with demulcent drinks. Also Inhalations of ammonia. Fowler's Solution. — Same as Arsenic. Gelsemium.— Coffee, brandy, emetic of ipecac. Hyoscyamus, Its preparations or deriva- tives.— Same as Belladonna. Indian Hemp. — Same as Belladonna. lodin and .Its preparations. — Give starch, white of egg or flour mixed with water, emetic or mustard. Give strong tea or coffee, stimulants (whisky, etc.). If needed, demulcent drinks. Lysol. — Give white of egg, starch or flour mixed with water, emetic of mustard. Give strong tea or coffee, stimulants (whisky, etc.). If needed, demulcent drinks. Nitroglycerin.— Cold to head. Horizon- tal position. Give emetics and cathar- tics. Ergot. Nux Vomica and Its preparation or de- rivatives.— Same as Strychnine. Oil of Bitter Almonds, Essential.— Cold water to head and spine. Give stimu- lants. Phosphorus and Its derivatives.— Emetic of mustard, or blue vitriol 3 grains every five minutes until vomiting oc- curs. A teaspoonful old thick oil of turpentine (avoid other oils); also ep- som salts, half ounce in tumberful of water. Pennyroyal, Oil of.— Give white of egg or flour mixed with water, emetic of mustard. Give strong tea or coffee, stimulants (whisky, etc.). If needed, demulcent drinks. Red Precipitate.— Same as Corrosive Sub- limate. Rue, Oil of. — Same as Pennyroyal. Savin, Oil of. — Same as Pennyroyal. Santonin. — Evacuate stomach, use stimu- lants and emetics. Strophanthus and Its preparations. — Give zinc sulfate and mustard as emetics. Also tannic acid. Stimulants (brandy or whisky). Epsom salt. Strychnine. — Emetic of mustard followed by large draughts of warm water. Give powdered charcoal. To relieve spasms let patient inhale pure chloroform or give chloral hydrate (25 grains). Sugar of Lead. — Give epsom salt (one-half ounce) dissolved in a tumblerful of wa- ter, emetic of mustard, large draughts of warm water, milk, demulcent drinks of flaxseed or slippery elm. Tansy. — Same as Pennyroyal. Tartar Emetic. — Give emetic of mustard or zinc sulfate. Milk, white of egg freely mixed with water. Veratrum, Viride and Its preparations and derivatives. — Emetic of mustard fol- lowed by large draughts of warm wa- ter. Then strong tea or coffee, stimu- lants' (whisky, etc.) freely. Keep pa- tient in horizontal position. apply warmth to the extremities, artificial respiration. White Precipitate— Same as Corrosive Sublimate. Wood Alcohol.— Give warm water and salt (two tablespoonfuls to a tumbler- ful) immediately. Repeat at short in- tervals. Stimulate the respiratory move- ment, and give strong coffee. 1036 THE STANDARD FORMULARY Zinc Sulfate. — Give white of egg. flour mixed with water, baking or washing soda, emetic of mustard. Give strong tea or coffee, stimulants (whisky, etc.). If needed, demulcent drinks. AQUARIUM CEMENT. See under Cements. AQUARIUM WATER, To Make. See under Sea Salt, Artificial. ARSENIC PASTE, DENTISTS'. See Dentists' Arsenic Paste. AXLE GREASES (Lubricants.) I. Plumbago, very fine pow- der av.oz. 4 Lard av.oz. 12 Mix well. II. Plumbago, very fine pow- der av.oz. 6 Petrolatum av.oz. 10 Mix well. III. Petroleum gal. 1 Tallow ' av.oz. 4 Palm oil av.oz. 4 Plumbago av.oz. 6 Caustic soda av.07. 1 These are mixed and heated together for an hour or more to a temperature of 8o° C, cooled, and then stirred well together after 24 hours. IV. Heat together 10 pounds of rosin oil and 8 pounds of lime, slaked and afterwards sifted fine. Stir the mixture constantly while heating, and continue the heating until the mixture is uniform and of the consistency of syrup. The resulting mixture is called rosin soap. Take I pound of this and 1 pound of palm oil, melt together, then stir in 50 pounds of rosin oil, and sufficient rosin soap to make the mixture of the con- sistency of butter. Lastly, add 34 pound of caustic soda, heat and stir until thoroughly combined. AXLE GREASE STAINS, Removal of. See Stains from Fabrics, Removal of. BAITS FOR ANIMALS. See Scents for Attracting Animals. BALL BLUING. See Bluing, Ball. BALLROOM FLOOR POWDER. See Floor Wax in Powder. BANANA OIL OR LIQUID. This preparation used by painters and others for gilding purposes, also as a solvent in making varnishes, is stated to be composed of 9 parts each of amyl acetate and butyric ether and 1 part of alcohol. By another authority it is said to be made as follows : Transparent celluloid av.oz. 1 Acetone, enough to dissolve. Amyl acetate, to make fl.oz. 20 Dissolve the celluloid by agitation. It should be cut into small pieces, if pos- sible, to hasten solution. BAROMETER GLASS, SOLUTION FOR. (Chemical Barometer — Baroscope Liquid.) There is a form of "barometer" which is quite common, usually being mounted in a frame with a thermometer, which is variously known as a storm glass, chemical barometer, domestic barometer, weather barometer, and by other catchy but inappropriate titles. The solution in the tube is usually of about the follow- ing composition : Ammonium chlorid gr. 30 Potassium nitrate gr. 30 Camphor gr. 30 Alcohol fl.dr. 8 Distilled water fl.dr. 9 Dissolve the camphor in the alcohol by agitation, the other solids in the wa- ter, add this solution (warm) to the camphor solution. This solution is always contained in a sealed glass tube which is about three- fourths filled. As the weather becomes cooler, a portion of the camphor sepa- rates from the liquid in different crys- talline forms which sometimes go to the bottom of the glass and sometimes re- main partially suspended in the liquid. These changes in the appearance of the liquid are ascribed by the makers of the storm glass to variations in pressure of the atmosphere, the "glass" therefore acting as a weather forecaster. How- DOMESTIC UTILITIES. 1037 ever, as indicated above the changes are due to temperature only and storm glasses are therefore entirely valueless for forecasting purposes. BAROMETER OR HYGROMETER PAPER. Barometer papers differ from the pre- viously mentioned storm glasses in that they actually indicate, though in a crude way, the proportion of moisture in the atmosphere and in this way foretell the possibility of early showers or of con- tinued dry weather. The basic sub- stance of these papers is a soluble salt of cobalt, the chlorid or nitrate, which has the property of changing in color from blue in dry weather to pink in moist weather. The following solution is a satisfac- tory one for making these papers : Cobalt chlorid Sodium chlorid .av.oz. 2 av.oz. I Calcium chlorid dr. iY 2 to 3 Water fl.oz. 6 Mix, dissolve and filter. In very dry regions, a larger amount of calcium chlorid must be employed than in moist- er regions. Glycerin may be substituted for the calcium chlorid, but the latter is to be preferred as the former is gradu- ally dissipated. To prepare the paper, soak white blot- ting paper in this liquid and then dry. The amount of moisture in the air is indicated by the following colors : Rose red rain Pale red very moist Bluish red moist Lavender blue nearly dry Blue very dry BARRELS IMPERVIOUS, To Make. The following composition was pat- ented in 1871 : 50 pounds of glue, 16 pounds of plaster of Paris, 10 ounces of alum, and }£ ounce of potassium iodid. Boil the mixture with sufficient water to give the required thickness. The mix- ture is to be applied hot and may be put on as thickly or thinly as desired. BATTERY FLUIDS. For bichromate batteries use Nos. I, II, III or IV. I. Mercury bisulf ate dr. 2 Potassium bichromate av.oz. 2^2 Sulfuric acid, crude ...fl.oz. 3 Water fl.oz. 16 In the water dissolve first the mer- cury salt and then the bichromate; then add the sulfuric acid very carefully, stirring constantly with a glass rod. When cool the solution is ready for use. The mercury keeps the zincs well amal- gamated. Sometimes the mercury salt is omit- ted, and frequently sodium bichromate is substituted for the potassium bi- chromate. II. Sodium bichromate av.oz. 2 Sulfuric acid, commercial. . .fl.oz. 2 Water fl.oz. 16 Pour the acid upon the bichromate, coarsely powdered, stir the mixture oc- casionally during an hour, then slowly add the water with stirring. According to the National Formulary, this solution is intended for ordinary use. Sodium bichromate is more soluble than the potassium salt and its products of decomposition, in the battery are also more soluble. As it is much cheaper, it is now preferred in large electric labor- atories. When it cannot be obtained, the potassium salt may be substituted for it, weight for weight. III. Sodium bichromate av.oz. 2% Sulfuric acid, crude fl.oz. 5 Water fl.oz. 16 Prepare like No. II. According to the National Formulary, this is intended for use with a galvano-cautery. BATTERY, STORAGE. A very satisfactory storage battery may be constructed in the following manner : After procuring two half- round porous cups and a glass jar suffi- ciently large to hold them both, get two 1038 THE STANDARD FORMULARY pieces of sheet lead one-sixteenth of an inch thick, wide enough to fit the half- round side of the porous cups, and deep enough to come an inch above the top edge of the cups and jar. Solder a screw post to each lead plate, nearly fill the cup with a paste consisting of red lead and a solution of sodium sulfate thin enough to run like a cement, and put the lead plates in place, one of them being marked with an +. Fill the outer jar to within half an inch from the top with a i :8 solution of sulfuric acid, and the battery is ready for charging. This may be done by attaching for 24 hours to a 12-cell copper sulfate battery, or to a dynamo; but always charge in the same direction. If well charged these storage cells will retain a large volume of electricity for a considerable time, and with a battery consisting of two or more cells small motors, lamps and in- duction coils may be operated, After the first charge a 5-cell battery suffices to recharge. BATTERIES, Filling for Dry. In the so-called dry batteries the ex- citing substance is a paste instead of a fluid; moisture is necessary to cause the reaction. These pastes are generally se- cret preparations. One of the earlier "dry" batteries consisted of a contain- ing vessel of zinc, which forms the positive element ; the negative one is a cylinder of carbon; and the space be- tween is filled with a paste, the recipe for which is: Zinc oxid part 1 Ammonium chlorid part 1 Zinc chlorid part 1 Plaster of paris parts 3 Water parts 2 The usual form of silver chlorid bat- tery is said to consist of a sealed cell containing a zinc electrode, the two be- ing generally separated by some form of porous septum. Around the platinum or silver electrode is cast a quantity of silver chlorid. This is melted and gen- erally poured into molds surrounding the metallic electrode. The exciting fluid is either a solution of ammonium chlorid, sodium or potassium hydroxid, or zinc sulfate. As ordinarily construct- ed, these cells contain a paste of the electrolyte, and are sealed hermetically in glass or hard rubber receptacles. Another "dry cell" is the following: I'n a containing vessel, generally of cardboard, is placed a zinc cylinder, and in the middle of this stands a carbon plate. The space between the zinc and carbon is filled with a jelly-like compo- sition as mentioned. The zinc is coated on the inner surface to the thickness of *4 inch with a paste made as follows : Plaster of paris av.oz. 1 Sal ammoniac dr. 3 Water av.oz. 2 The carbon is then put in, care berig taken that it does not touch the zinc, and the remaining space is filled in with the following mixture: Carbon, powdered (or gra- phite) av.oz. 3 Black oxid of manganese, coarsely powdered dr. 3 Zinc sulfate dr. V/2 Sal ammoniac dr. 5 Glycerin gr. 40 Water, sufficient to make a stiff paste. The cell is afterwards sealed up with melted pitch, ventholes being provided by inserting two pieces of thick wire, and removing them when the pitch is cold. There are many different makes of dry battery, but the compositions used probably do not differ to any great extent from that just given. If to be used for producing electric light it may be said that such cells, no matter what size, have each an E. M. F. of about i]/ 2 volt; but taking into ac- count their internal resistance (unless very large), one would not be far out in reckoning the available pressure of each cell as 1 volt, so that to light a 5-volt lamp well one would require 5 cells, and so on. Two or more similar lamps would be arranged in parallel, and would not require any more cells than one lamp : but the cells should be larger in proportion to the number of lamps. DOMESTIC UTILITIES. 1039 In fact, the larger the cells the greater the current that may be taken, and the longer will the current last; but, in any case, such cells are only adapted for lighting lamps for a short time (a few minutes) at comparatively long inter- vals. BAUME'S SCALE. To convert Baume's degrees to speci- fic gravity, the following may be em- ployed : I. For liquids lighter than water, add the degree Baume to 130 and divide the sum into 140, viz. : 45 ° = 140 -r- (130 + 45) = 140 + 175 = 0.80 sp. gr. II. For liquids heavier than water, sub- tract the degree Baume from 145 and divide into 145, viz. : 29 B — 145 -r- (145— 29) =145 -7- 116=1.25 sp. gr. BEDBUG EXTERMINATORS. The number of "cures" for bedbugs is legion. The following list embraces some of the substances employed for their destruction: Oil of turpentine, kerosene, benzin, mercuric chlorid, mer- cury, Paris green, zinc chlorid, arsenic, insect powder, Scotch snuff, capsicum, naphthalin, camphor, sulfur fumes, am- monia vapor, hydrocyanic acid vapor, soft soap, carbolic acid (both pure and crude), colocynth, wormwood, aloes, pepper, sodium borosalicylate, cimici- fuga root ; also fresh sprays of strongly- scented plants, such as ledum palustre, pennyroyal, tansy, pine, etc., placed be- neath the mattress. Bedbug exterminators may be in the powder, the liquid or the paste form. The powder may be the well known in- sect powder, or it may be Paris green, or it may be a mixture of different in- secticides. Sometimes these powders are made into a paste by moistening and are pressed into cracks containing, or suspected of containing, bedbugs or their eggs. If the powders are used in the dry form, they may be introduced into the crevices by means of an insect powder blower or "gun." The liquid exterminators may consist of poisonous solutions like those con- taining corrosive sublimate or carbolic acid, or they may consist of oil of tur- pentine, kerosene, benzin, oil of cedar, etc., or they may consist of tinctures of bitter substances like coloycnth or quas- sia, or they may consist of resinous so- lutions, or they may consist of soapy solutions, or again they may consist of several of these classes of substances in combination. Substances like kerosene, benzin, vol- atile oils, etc., act by dissolving the chit- inous coating of insects and thus ob- structing the breathing pores and cause death. The resinous substances act largely by cementing over the eggs and thus prevent their hatching. The bitter substances mentioned are usually de- structive to insect life. The objections to these different sub- stances for exterminative purposes are that resins, oil of turpentire, etc., leave stains, benzin, kerosene, etc., are inflam- mable, corrosive sublimate, Paris green, etc., are excessively poisonous, carbolic acid has an unpleasant odor, etc. The evils of the different substances are often mitigated by combining several of them. Liquid exterminators may be applied by means of a brush or feather, but a better method is to employ a machinist's oil-can or a bottle containing a perfor- ated cork in which is inserted a quill. Corks which are perforated and are provided with a tin spout are now also to be had. I. One of the most commonly-used bedbug exterminators is the following : Corrosive sublimate av.oz. 1 Alcohol fl.oz. 3-' Or some of the alcohol may be re- placed by water. However, inasmuch as it is the alcohol and not the mercury chlorid that is presumed to be the in- secticide, this replacement is not to be recommended. Very frequently a por^ 1040 THE STANDARD FORMULARY tion of the alcohol, from about 20 to 80%, is replaced by oil of turpentine; this reacts with the corrosive sublimate, precipitating the latter. Oil of turpentine alone is an excellent bedbug destroyer. The alcohol may also be replaced by wood alcohol or denatured alcohol. A good mixture is the one following this (No. II). II. Corrosive sublimate av.oz. 1 Wood alcohol fl.oz. 24 Oil of turpentine fl.oz. 8 Oil of cedar fl.oz. 1 Dissolve the corrosive sublimate in the alcohol and add the oils. III. Corrosive sublimate dr. 2^ Ammonium chlorid dr. 5 Decoction of quassia (about 1 in 20) fl.oz. 32 Mix and dissolve. — H. IV. Common soap Ammonium chlorid Corrosive sublimate Water, to make. . . . ..av.oz. 1 ..av.oz. I ..av.oz. 1 . . .fl.oz. 32 Dissolve the two salts in a portion of the water, the soap in the remainder of the water and mix the two liquids. Green or soft soap may be used if de- sired. A portion of the water may be replaced by oil of turpentine or kero- sene or it may be entirely replaced by decoction of quassia or of white helle- bore. Paris green or London purple may be added to the mixture if desired. V. Xaphthalin av.oz. 1 Gasoline fl.oz. 16 Mix and dissolve. This is efficacious, is dangerous to use on account of the in- flammability of the gasoline. This mix- ture may be used indiscriminately on bedding, furniture, textiles of all de- scriptions, wall-paper, etc. It may be improved by adding one ounce or so of resin or paraffin wax, which acts by forming a coating over the eggs of the insects and preventing their hatching out BENGAL LIGHTS. These are the same as "colored fires." See Fires, Colored. BENZIN JELLY (Gelatinized Ben- zin.) This is benzin made into the form of a soft jelly by combination with soap or soap bark decoction or tincture. The soap, ammonia water, ether, and similar ingredients in the mixture add to the detergent properties of the benzin. The jelly is useful for cleaning gloves, rib- bons, and fabrics generally, for remov- ing greasy, oily, resinous, and other kinds of stains. The directions for use are to rub the spot or stain with a sponge or suitable cloth saturated with the jelly, allowing to remain for a few minutes, then rins- ing in warm water. If the stain is not removed, repeat the operation. Those who intend using this kind of a preparation should be warned against the inflammability of benzin or any mixture containing any considerable proportion of it. The cleanser should preferably not be used at night nor in proximity to lights or fires. Other cleaning preparations are men- tioned under the headings Carpet Clean- ers ; Cleansing Preparations ; Ammonia, Household; Soap, Ox-Gall. I. Hard soap, white .av.oz. 3 Water, boiling fl.oz. 5 Stronger ammonia water. . .fl. dr. 6 Benzin fl.oz. 26 Dissolve the soap in the water, and when nearly cold add the ammonia and the benzin, and then perfume to suit. Soaps with an excess of alkali give the best results. II. Castile soap av.oz. 4 Stronger ammonia water. . .fl.oz. 1 Benzin fl.oz. 8 Water, to make fl.oz. 2> 2 Dissolve the soap in a portion of the water by the aid of heat, add the am- monia water and enough water to make 24 fluidounces, and then shake with the benzin. DOMESTIC UTILITIES. 1041 III. Castile soap av.oz. 2 Benzin fl.oz. 6 Stronger ammonia water. . .fl.oz. 6 Water, to make fl'.oz. 20 Shave the soap into very fine pieces, and heat it on a water bath with 8 fluidounc.es of water until soft and jelly- like, then adding water to make 8 fluid- ounces. Mix well, strain through cheese- cloth into a wide-mouthed bottle, add the benzin, shake well, then add the am- monia water gradually with constant agitation. IV. Castile soap, white dr. 1 Alcohol fl.dr. 4 Glycerin fl.oz. 1 Ammonia w r ater fl.oz. 1 Ether fl.oz. 1 Water, to make fl.oz. 16 Benzin sufficient. Dissolve the soap in a portion of the water, then add the remaining ingredi- ents. Into a wide-mouthed bottle of 16- ounce capacity put lYz ounces of this liquid and to it add benzin, little by little, shaking thoroughly after each ad- dition, until no more will be -taken up and a creamy mixture results. V. Cocoanut oil soap av.oz. 2 Ammonia water fl.oz. 3 Solution of potassa fl.oz. i l / 2 Water, to make fl.oz. 12 Dissolve the soap with the aid of heat in 4 fluidounces of water, add the am- monia and potassa and the remainder of the water. If the benzin is added in small por- tions, and thoroughly agitated, 2Y2 fluid- ounces of the above will be found suffi- cient to solidify 32 fluidounces of ben- zin. VI. Stearin soap av.oz. 4 Cocoanut soap av.oz. 2^4 Ammonia water fl.bz. 2 Water, distilled . fl.oz. 24 Benzin fl.oz. 9 Shave the two soaps into fiqe pieces and dissolve them on a water-bath in the water. To the solution add the am- monia water and then t'ie benzin, stir- ring vigorously and frequently during cooling to insure a uniform creamy mixture. — D. VII. A co-called "benzin paste" for the re- moval of stains both from the hands and clothing may be made as follows : Melt 100 parts of stearic acid at 30 to 50 C, and add to it 40 parts of 15.6% of caustic potash solution, stirring well; then add to the semi-solid mass at the above temperature, 8 to 10 parts of strong ammonia water ; mix well, and stir in 40 parts of melted tallow. Final- ly add benzin enough to convert the whole into a nice, smooth paste. VIII. A preparation of an agreeable odor and of equal value as a cleansing agent may be made according to any of the preceding formulas by substituting pure or purified benzole for benzin. BENZINE, Purifying of. Benzine, as well as other petroleum distillates, may be purified by the proc- ess of the U. S. P. which is given in Part I. The following is another process : Add to the benzine 1 or 2% of oleic acid, which dissolves, and then Va% of aqueous solution of tannin which incorporate by thorough agitation. A quantity of solution of caustic potash or milk of lime sufficient to combine with the acids is then well shaken with the mixture and the whole allowed to stand. The benzine rises to the top of the aqueous liquid, suffiicently deodor- ized for all practical purposes. BENZINE, Disguising- Odor Of. The following process has been pat- ented in Germany for disguising the odor of benzine and other petroleum distillates : Add to the liquid a volatile oil containing a terpen such as oil of turpentine, fennel, caraway, lavender, pine needles, eucalyptus, etc., and then an alkali. If the benzine be mixed with 1% of oil of fennel, wanned to 70 C, then agitated with - T solution of soda, sp. gr. about 1.30, and 1042 THE STANDARD FORMULARY allowed to stand till the benzine sepa- rates from the aqueous liquid, the for- mer will have merely an odor of fennel. BENZINE, Non-Inflammaole. So-called non-inflammable benzine is a mixture of tetrachlorid of carbon with benzine. A mixture of 7 parts of the tetrachlorid with 3 of benzine have been advised, but even this is considered in- flammable by some so that a still larger proportion of carbon tetrachlorid is ad- vised. BICYCLE CHAIN LUBRICANT. The best lubricant for bicycle chains is plain dry powdered graphite, or plumbago. This is brushed over the chain previously cleaned by immersion in kerosene, rubbing with a rag, an- other bath in the kerosene, followed by one in lard or sperm oil, and then rub- bed thoroughly dry. The surplus plum- bago thereupon is also removed by gen- tly wiping the chain with a rag. In order to apply the plumbago more eas- ily, some riders are in the habit of mak- ing it into a stiff paste with oil or grease, while others mix it with kero- sene or oil of turpentine. Mixtures with glycerin also are recommended. Some like a composition of 2 to 3 parts of the powder with 5 parts of petrolatum. However, there is a great demand for stick lubricants. These are made by in- corporating a sufficient amount of plum- bago with a hard fat, such as tallow or tallow with a little wool- fat. The white lubricants are crude soaps, of which the following is an example : Tallow part 1 Palm oil, crude parts 2 Solution of sodium carbon- ate, 15% part 1 Melt together and pour the mass into tin canisters. BICYCLE ENAMEL. This enamel is waterproof and wears well; it imitates closely the natural blue of steel, and it can be removed with a cloth soaked in alcohol at any time. It will keep indefinitely when tightly cork- ed, and may be used on any metal as it will not corrode it. Bleached shellac parts 5 Borax part 1 Alcohol parts 5 Water parts 4 Methylene blue sufficient Dissolve the borax in the water and the shellac in the alcohol by maceration, reserving a small portion of the latter to dissolve the methylene blue. Heat the watery solution to boiling and add the alcoholic solution, stirring constant- ly ; starin out any lumps and add the blue solution. Paint with a soft brush on the spokes, which have been cleaned bright with emery cloth. The quantity of blue need- ed is very small ; by grading the amount employed any shade from a dark blue to a light steel color may be obtained. Orange shellac can be used, but it gives a greenish cast to the enamel. BICYCLE OIL, Illuminating. Various mixtures are used, such as equal parts of kerosene and lard oil, or equal parts of kerosene and comphor- ated oil; or equal parts of sperm oil, lard oil, and kerosene. Kerosene and sperm oil are also used. Formulas with camphor are frequently recommended, such as the following : Gum camphor part 1 Sperm oil parts 8 Paraffin oil parts 24 BICYCLE OIL, Lubricating. Various combinations are recommend- ed, such as a mixture of equal parts of kerosene and castor oil or 1 part of ker- osene and 2 parts of sperm oil. Ordi- nary yellow paraffin oil may be used as a lubricant. Another good combination is a mix- ture of Camphorated oil part 1 Sperm oil parts 3 Paraffin oil parts 4 This mixture is equally useful for lub- ricating and illuminating purposes. The following has been patented in Germany: Olein, parts 12, rosin, parts DOMESTIC UTILITIES. 1043 4, petrolatum oil, parts 10, castor oil, part I ; mix by melting, stirring till solidified. It is to be applied cold to the axle. The motion of the wheel in- sures its even distribution. BICYCLE PAINT (Glossy Black.) Amber av.oz. 16 Linseed oil, boiling fl.oz. 8 Asphaltum av.oz. 3 Resin av.oz. 3 Oil of turpentine fl.oz. 16 Melt the amber in the boiling oil and add the asphaltum and resin. Mix thor- oughly, remove to the open air, and gradually add the turpentine oil. This is useful for metallic surfaces, such as on bicycles. See also the similar "black varnish" under Varnishes. BICYCLE TIRE CEMENT. See under Cements. BIRD LIME, Artificial. Artificial bird lime is said to be made by boiling linseed oil and then igniting it. Another good preparation is ob- tained by mixing a strong solution of cabinetmaker's glue in water with a con- centrated solution of zinc chlorid. Other preparations for the same purpose are the following: I. Linseed oil fl.oz. 3 Burgundy pitch av.oz. 7 Melt the pitch and incorporate with the oil. II. Rosin av.oz. 5 Burgundy pitch av.oz. 2^ Rapeseed oil fl.cz. 3^2 Prepare like the preceding. III. Rosin av.oz. 4 German turpentine av.oz. 2 Rapeseed oil fl.oz. 2 Honey dr. 2 Prepare like No. I. BLACK ENAMEL. See Bicycle Paint. 66 BLACKBOARD SLATING OR PAINT. In preparing these paints it is essen- tial that the insoluble substances be re- duced to very fine powder and that they be thoroughly incorporated in the mix- ture, and also that they be kept in a state of suspension, during the process of application, by constant agitation. Of course, much depends upon the skill of the painter, for unless he pre- pares the surface of the board or wall well before putting on the paint, the latter cannot be expected to appear to the best advantage. Two coats are us- ually to be preferred to one, and un- even surfaces, after either coat has been applied should be rendered smooth by rubbing with sandpaper or 'emery cloth. On account of the rapid-drying prop- erties of these paints, they should be ap- plied quickly with a broad, flat brush. I. Lampblack av.oz. 1 Pumice stone, powder av.oz. 4 Boiled linseed oil fl.oz. 8 Oil of turpentine, to make.. fl.oz. 32 Mix well to make a smooth paste. II. Shellac av.oz. 4 Lampblack av.oz. 1 Emery flour av.oz. 1 Ultramarine blue av.oz. 1 Alcohol fl.oz. 32 Dissolve the shellac in the alcohol. Place the lampblack, emery and ultra- marine blue on a cheese-cloth strainer, pour on part of the shellac solution, stirring constantly, and gradually adding the solution until all of the powders have passed through the strainer. III. A preparation of this kind was patented in the United States in 1S72. The proportions mentioned in the patent were as follows : Shellac av.oz. 6 Emery flour av.oz. 4 Ivory black av.oz. 2 Alcohol fl.oz. 32 If the board is used exclusively for chalk, the emery flour may be reduced one-half. 1044 THE STANDARD FORMULARY IV. The following differs materially from any of the preceding : Borax, powder av.oz. 2 Lampblack av.oz. 2 Orange shellac av.oz. 8 Pumice stone, fine pulver- ized av,oz. 5 Water fl.oz. 32 Heat the water to boiling, in it dis- solve the borax and add the shellac which under continued heating will dis- solve. From time to time add water, if necessary, to make up for that lost by evaporation. Now add the pumice stone and the lampblack, first rubbing the lat- ter up with a portion of the liquid to a smooth paste, and stir the whole until well mixed. Pass the mixture through a fine sieve to remove any possible lumps, and add more water to reduce to the proper consistency. This liquid may be painted on wood ; metal, pasteboard, or even a plastered wall, providing the surface is sufficiently smooth. It should be applied with a soft, flat brush. BLACKING FOR SHOES. See Shoe Blacking, Liquid and Shoe Blacking, Paste Form. BLACKING FOR STOVES. See Stove Polish or Blacking. BLEACHING FEATHERS. See Feathers, Bleaching of. BLEACHING IVORY. See Ivory, Bleaching of. BLEACHED SPONGES. I. The following is the process of the National Formulary for bleaching sponges : Free the sponges to be bleached from sand and any other obvious impurities or damaged portions by beating, wash- ing and trimming, then soak for about 15 minutes in a sufficient quantity of so- lution of potassium permanganate, con- taining one-half av. ounce to the quart, wringing the sponges out occasionally and replacing in the liquid. Then re- move and wash with water, until the latter runs off colorless. Wring out the water and then place the sponges into a solution of sodium hyposulfite, contain- ing 2 av. ounces to the quart. Next add for every quart of the last named solu- tion used, 2 fluidounces of hydrochloric acid mixed with 8 fluidounces of water. Macerate the sponges in this liquid for about 15 minutes, expressing frequently and replacing in the liquid. Then re- move and express, and immerse for a short time in a 10% solution of sodium carbonate, again expressing. Finally, wash the sponge's thoroughly with water and dry them. In the case of large and dark-colored sponges it may be necessary to repeat this treatment to bleach them suffici- ently. If it is desired to keep the sponges soft, and to prevent them from shrink- ing when dry, they may be dipped, after being finally washed, into a mixture of 1 volume of glycerin and 5 volumes of water, after which they may be wrung out and allowed to dry. II. Dissolve 1 dram of potassium permanganate in one-half gallon of wa- ter, introduce the sponges into this solu- tion, allow to remain for 24 hours, then remove and express, and introduce into another consisting of 5 drams of sodium sulfite dissolved in one-half gallon of water. While the sponges are soaking in this solution, stir into it one fluid- ounce of crude muriatic acid. Express the sponges frequently, returning to the liquid until well bleached. Then express again and wash thoroughly in warm wa- ter. To make certain that every trace of acid has been removed from the sponges, the latter should be soaked in a solution of 2^ drams of sodium thio- sulfate (hyposulfite) in x /2 gallon of water. The use of alkalies for the lat- ter purpose is not to be recommended, as these have a tendency to produce a brownish discoloration. If the sponges are intended for surgi- cal purposes, they should first be freed from sand by beating and shaking, after which they should be macerated for 24 DOMESTIC UTILITIES. 1045 hours in a 2% dilution of crude hydro- chloric acid. After thorough expres- sion and washing with warm water, they are ready for the permanganate treat- ment. III. The sponges are first immersed for a few minutes in a mixture of 1 part muriatic acid and 20 parts of water to remove calcareous matter. Wash out all the acid and treat with a solution of 1 part potassium permanganate to 45 of water, allowing the sponges to remain in this until fully saturated. Transfer from this, without rinsing, to the fol- lowing: Oxalic acid, 1 part, sulfuric acid, 1 part, water, 50 parts. Remove from this as soon as the permanganate is decomposed. The sponges are now bleached, but which will not remain so unless treated with a weak alkali. A solution of sodium bicarbonate, 1 to 20, is recommended. IV. The bromin process appears to be preferred in Germany. According to this the sponges, first freed from cal- careous portion by trimming with a sharp knife or shears, are immersed in a saturated solution of bromin in water (about 1 in 30), taking care that there is no undissolved bromin. Allow the sponges to soak for several hours when their own color as well as that of the liquid becomes decidedly lighter. If nec- essary, the sponges may be given a sec- ond or even a third bath in bromin water. A final dip in very dilute sul- furic acid improves the sponges. The latter should be well washed in water to remove all the bromin odor, after which they are to be dried. BLEACHING OF LINSEED AND POPPY SEED OILS. Mix 1 quart of the oil in a bottle with a solution of 5 drams of potassium per- manganate in 1 pint of water, shake thoroughly, set aside for 24 hours in a warm place, and then add 1 av. ounce of sodium sulfite in coarse powder. Agi- tate the whole thoroughly until the lat- ter is dissolved, and incorporate 10 fluidrams of crude hydrochloric acid. Shake frequently until the brown liquid has become quite light in color, and wash the oil with water containing a small amount of chalk until the wash- ings are no longer acid. After separat- ing all the water, the oil may be filtered through dried sodium sulfate. BLEACHED SHELLAC. Mix 1 av. pound of chlorinated lime with 5 gallons of water in a hardwood tub and to this add 5 pounds of orange shellac which has previously been re- duced to coarse powder. After 24 hours stir in a mixture of 5 pints of water and 20 minims of sulfuric acid, and then 30 pints of boiling hot water. The bleach- ed shellac, which rises to the surface, is to be removed from the liquid, kneaded with hot water till free of lime, chlorin and acid, and then formed into sticks. BLUE PRINTING PAPER. The mixture which is to be applied to the paper consists of 2 (sometimes 3) solutions which are to be mixed just prior to use. I. No. 1. Potassium ferrocyanid ...av.oz. 1 Distilled water fl.oz. 10 No. 2. Citrate of iron and am- monium av.oz. 3 Distilled water fl.oz. 10 Gum arabic or dextrin dr. 2 Keep these solutions in separate, well- stoppered bottles in a dark place. The- function of the gum or dextrin is to keep the solution on the paper. II. No. 1. Iron citrate, soluble av.oz. I Distilled water, to make fl.oz. 4 l /> No. 2. Potassium ferrocyanid av.oz. Y± Distilled water, to make . . . tl.oz. 4 T 2 No. 3. Potassium bichromate gr. 23 Distilled water fl.oz. 4 1 a Mix Nos. 1 and 2, add No. 3! filter quickly, and use immediately. The iron 1046 THE STANDARD FORMULARY citrate should be in scales, free from powder, and should not have been ex- posed to light. The ferrocyanid must also be free from any adherent powder. To coat the paper. — This must be done by gas light. Pour some of the solution into a saucer, dip a soft pad of absorbent lint into it and pass quickly across the paper; again dip the pad in solution and pass across the paper from where it was left off. When all the paper has been thus coated take an artist map varnish brush and remove the excess of liquid. Keep these solutions in separate well- stoppered bottles, which exlude actinic light. In using, mix equal parts of Nos. I and 2. Tn preparing the sensitized paper, take a solid, firm paper, free from impuri- ties, and apply the solution to the sur- face of the paper with a soft sponge or a broad, soft brush, being careful not to have the sponge or brush charged too heavily with the solution, or else the paper will have a streaked appearance, which will show in the finished print. Go over the surface of the paper in two directions at right angles to each other so as to insure an even coating. The paper must be allowed to dry in the dark, and in a horizontal position. III. No. i. Iron and ammonium citrate. . .dr. 4 Distilled water, to make fl.oz. 2 Xo. 2. Potassium ferricyanid dr. 4 Distilled water fl.oz. 2 For use, mix equal parts of the two solutions. IV. Potassium ferrocyanid dr. 5 Iron and ammonium citrate.. dr. 7^4 Ammonia water m. 30 Distilled water fl.oz. 6 Dissolve the ferrocyanid in the water, add the ammonia, and then the iron and ammonium citrate, and stir until a clear solution is produced. This liquid is to be used at once. V. The following is said to keep much better than the ordinary commer- cial makes : Solution No. 1. Gum arabic dr. 3 Ammonio-citrate of iron dr. 4^2 Tartaric acid dr. 3 Ammonia water fl.dr. 6 Distilled water fl.oz. 4 Dissolve the solids in the water by agitation in a bottle or trituration in a mortar, then add the ammonia. Solution No. 2. Potassium ferrocyanid gr. 225 Distilled water fl.oz. 2 For use, mix Nos. 1 and 2. This solution, which must be kept in the dark, should be applied to the paper with a soft, broad brush by artificial light and then dried in the dark. It is exposed under a negative in the ordi- nary way till the half-tones show a dark violet color, and it is then placed face downwards on water for about 10 sec- onds and removed, and exposed to the air for a short time, thoroughly washed in water and then immersed in a bath of Javelle water fl.oz. 1 Water fl.oz. 20 till it turns a deep blue. VI. The following process is that of Capt. Abney and yields a photographic paper giving blue lines on a white ground : Table salt gr. 140 Ferric chlorid .gr. 375 Tartaric acid gr. 152 Acacia av.oz. 2^2 Distilled water fl.oz. 10 Dissolve the acacia in half the water, the other ingredients in the remainder of the water, and mix the two solu- tions. The liquid is to be applied, as evenly as possible, with a brush to strongly- sized paper, in a subdued light. The paper should be dried rapidly to prevent the solution sinking into its pores. In sunlight, one or two minutes is generally sufficient to develop an image, while in dull light as much as an hour may be necessary. DOMESTIC UTILITIES. 104:7 To develop the print it is floated im- mediately after leaving the printing frame upon a saturated solution of po- tassium ferrocyanid. None of the de- veloping solution should be allowed to reach the back. The development is us- ually complete in less than a minute. The paper may be lifted off the solution when the face is wetted, the develop- ment proceeding with that which ad- heres to the print. A blue coloration of the background shows insufficient expo- sure, and pale-blue over exposure, When the development is complete, the print is to be floated on clean water, and after 2 or 3 minutes, placed in a bath, made as follows: Sulfuric acid fl.dr. 2^ Hydrochloric acid fl.dr. 6 l / 2 Water fl.oz. 10 In about 10 minutes the acid will have removed all iron salts not turned into the blue compound. It is next thor- oughly washed and dried. Blue spots may be removed by a 4% solution of caustic potash. The back of the tracing must be plac- ed in contact with the sensitive surface. BLUING, BALL. This is said to be made from a mix- ture of 1 part of borax, 1 part of gum arabic, 2 parts of carbolic acid, 16 parts of Prussian blue, and sufficient water to form a dough; form this into balls of any suitable size, and dry them. BLUING OF COPPER. See Copper, Bluing of. BLUING OF GUN BARRELS. For bluing of gun barrels in imita- tion of the blue color imparted by heat, the following process is offered : Sodium hyposulfite av.oz. 4 Lead acetate av.oz. 1 Water pints 2 Dissolve the salts each separately in one pint of water then mix the solu- tions, and apply the mixture hot to the gun barrel. The surface of the bar- rel should previously have been entirely freed from oil or grease by wiping the surface with solution of potassa. When the color has developed, wipe the metal dry and polish with oil. BLUING, LIQUID. Prussian blue av.lb. 1 Oxalic acid av.oz. 4 Water gall. y 2 After solution is effected, dilute as much as desired. Soluble blue or blue aniline may also be employed for making this prepara- tion. Another preparation which may be employed is a solution of 1 part of indi- go-carmine in 10 parts of water. "BOILER COMPOUNDS" for Pre- venting Incrustation. A great many substances are recom- mended as useful in preventing the lime and magnesium salts of water from forming hard scales on the interior of steam boilers, and all act by preventing the agglutination of the particles, the salts remaining suspended in the water or being precipitated as soft mud. Sodi- um carbonate, or soda ash, ammonium chlorid, molasses, glucose, spent tan bark, slippery elm bark, lime, terra japonica, sodium fluorid, trisodium phosphate, etc., are other substances which are recommended for this pur- pose. There are many secret or proprietary combinations for preventing incrusta- tions on the market for which ex- traordinary claims are made, but gen- erally these are useful for only one kind of water and are totally unfit for every other kind. Some compounds prevent incrustation but cause so much corrosion that more harm is done than if no "compound" were used. Each "boiler compound" should really be specially compounded to fit the water to be treated. Furthermore the proper amount of "compound" should always be used as too little does not prevent the formation of scales and too much may corrode the boiler or it may raise the temperature of the water too high. besides being that much of a waste. Sodium fluorid is said to have no ad- 1048 THE STANDARD FORMULARY vantage over sodium carbonate and is much more costly. It precipitates lime and magnesium salts in a light, floc- culent form. Trisodium phosphate has been highly lauded as a "boiler compound" ; it con- verts soluble lime and magnesium salts into insoluble phosphates which remain in suspension for a long time on ac- count of their low specific gravity and then settle as a soft inud. On account of its. alkaline nature, it neutralizes any acids present which may cause cor- rosion. An excess of it is not likely to cause foaming as in the case of sodium carbonate. The use of sodium bichromate has been patented in Germany. It precipi- tates the lime and magnesium salts as insoluble, non-scaling chromates. It is said that an excess of this chemical or even of free chromic acid will cause no corrosion. Tannin is used to some extent. It precipitates the lime and magnesium salts in a satisfactory form but it has a corrosive action on the iron. Sugar and saccharine substances are also used as these precipitate the salts in a floccu- lent form. Such substances as sawdust, starch and potatoes act in a mechanical man- ner. Sawdust furnishes a nucleus or center for the salts as they crystallize to prevent them from uniting together. Starchy substances like potatoes act by forming a coating on the minute scales to prevent them from hardening. These substances have the disadvantage of causing foaming. A substance like tan bark acts both chemically and me- chanically. The following mixtures have been offered as "boiler compounds." I. Catechu av.lb. 2 Sal soda, crystal av.lb. 2 Dextrin av.lb. I Potash, crude av.oz. 8 Alum av.oz. 8 Sugar av.oz. 8 Gum arabic, common av.oz. 8 II. Turmeric av.lb. 2 Sodium bicarbonate av.lb. 2 Dextrin av.lb. 1 Potash, crude av.oz. 8 Alum av.oz. 8 Molasses av.oz. 8 The foregoing amounts are for a 5-horse power boiler, and for water rich in lime. The next is for river water, 100-horse power boiler, and must be renewed whenever the boiler is emp- tied : III. Sal soda, crystal av.lb. 2 Dextrin av.lb. 2 Alum av.lb. 10 Sugar av.lb. 10 Potash, crude av.lb. 5 IV. A United States patent for a "boiler compound" mentions the fol- lowing formula : Black treacle lb. 20 Wattle bark lb. 10 Shreds or shavings of leather lb. 5 Licorice root lb. 2 Caustic soda lb. 15 Boil this mixture for 5 hours with sufficient water to make 40 gallons of li- quid. BOTTLE CAPPING OR SEALING MIXTURES. These preparations are generally made either a gelatin or a resin basis and re- quire to be heated before they are applied. They may be colored before use to improve their appearance. Gela- tinous mixtures should be preferred for alcoholic liquids, while resinous liquids should be used for aqueous liquids. Gelatinous Mixtures. These are made with either gelatin or glue in combination with water and other ingredients, frequently contain- ing glycerin. They may be tinted blue, red, purple, or other colors with water- soluble aniline dye. Solution of carmine or tincture of cudbear may be used for coloring the mixture. Mix the mixture before use by the ap- plication of a gentle heat. The cap DOMESTIC UTILITIES. 1049 may be stamped while still soft with a slightly oiled die. I. Gelatin av.oz. I Gum arabic av.oz. I Starch av.oz. I Boric acid gr. 20 Water fl.oz. 16 Mix the gelatin, gum and acid with 14 nuidounces of cold water, stir oc- casionally until the gum is dissolved, heat the mixture to boiling, remove the scum and strain. Also mix the starch intimately with the remainder of the water, and stir this mixture into the hot gelatin mixture until a uniform product results. The latter may be tinted with any suitable aniline d>e. II. Gelatin av.oz. 3 Glycerin fl.oz. 2 Water fl.oz. 9 Select a clear grade of gelatin, add the • water, let stand till the gelatin is softened, liquefy by heating gently, and incorporate the glycerin. Color as may be desired as described above. More glycerin may be added if a softer mixture is desired. Glue may be used for a portion of .the gelatin which may be white or brown. III. Put a weighed amount of dry glue or gelatin in water, and let it stand over night. In the morning drain and press off all the surplus water, and then dissolve the swollen mass by heat- ing in a water bath. Add while still in the bath about one-half as much gly- cerin as there is liquefied gelatin, and for every av. pound of gelatin employed add 1 av. ounce of tannic acid, and stir until entirely homogeneous. Test the liquid on a piece of glass, and if when cold, it is too hard or brittle add somewhat more glycerin, and if too soft more glue and tannin, preserving the proportions indicated. If desired to color the mixture any of the mineral colors (rose pink, ucmenian bole, chrome yellow, etc.) may be added to make an opaque mixture, or an ani- line dye may be added to make a semi- transparent mixture. Resinous Mixtures. The regular sealing waxes may be employed for sealing bottles. See Seal- ing Wax. The following are somewhat different. IV. Venice turpentine av.oz. 3 Shellac av.oz. 5 Rosin av.oz 9 Melt together and color with lamp- black, ucmenian red, ucmenian bole, ul- tramarine blue, vermilion or otherwise. V. Rosin av.oz. 4 Yellow wax av.oz. 9 Melt together and color with lamp- black, ultramarine blue, vermilion, or other mineral color. VI. White wax av.oz. 8 Bismuth subnitrate av.oz. 1 Melt the wax at a gentle heat and stir in the bismuth subnitrate to form a smooth mixture. This makes a nice white cap. The mixture should be kept constantly stir- red. The application must be repeated several times until sufficiently thick. BOTTLES, Cleaning Greasy. The following preparation is an effi- cient solvent for grease in obstinately dirty bottles : Castile soap, in shavings. . .av.oz. 4 Sodium carbonate av.oz. 2 Borax av.oz. 1 Ammonia water fl.oz. 7 Alcohol fl.oz. 3 Sulfuric ether fl.oz. 2 Soft water, to make gal. 1 The soap should be boiled in the water until it is dissolved, and the other ingredients then added. Oily and greasy bottles need hardly ever be thrown away if they are prop- erly cleansed. The above mixture will suffice in most instances, although sim- pler or cheaper methods may first be tried. Volatile oils may be removed frequently by rinsing with wood alco- hol It is better to use this in several 1050 THE STANDARD FORMULARY small amounts rather in one larger quantity. If the bottle be an old one and the oil has become resinified, the bottle should be rinsed with strong sul- furic acid, then with clear water. Bottles which have contained fixed oils may be cleansed by putting in some lye or salt of tartar, adding a small amount of water to make a concen- trated solution, agitating thoroughly, then rinsing several times with clear water. Another method is to put saw- dust into the bottle, then to add am- monia water several times, shaking out after each addition of ammonia, and finally rinsing with clear water. An- other method of cleaning bottles which have contained fixed oil is to put in a little ground soap bark and shake up with water. If this is not effective use stronger agents such as lye or salt of tartar or the mixture mentioned above. Another method of cleaning bottles that have contained various volatile oils is to put in some linseed meal, in about the proportion of one ounce to a 16- ounce bottle, allowing the meal to ab- sorb as much oil as possible, then add a little water, shaking well. Fill the bot- tle with water, shake well, empty, rinse with clear water, and the bottle will be clear and free from odor. This method is said to clear out any oils which are not oxidized on the inside of the bottle. BRASS PLATING. See Plating with Gold, Silver, etc. BRASS, POLISHES FOR. See also Putz Pomades, Putz Tablets, Metal Polishes, Polishing Powders, and Polishing Cloths. I. Oxalic acid av.oz. 2 Pumice stone, powder av.oz. 4" Water, to make fl.oz. 16 Dissolve the acid in the water previ- ous to adding the pumice. Apply, after shaking, with a rag, and polish with a second dry woolen rag. II. This method is said to be used in the United States arsenals : Dip the article in a mixture of 2 parts of com- mon nitric acid and 1 part of sulfuric acid, contained in a stone jar. The articles, after being dipped in this mix- ture, are thoroughly washed with water and then rubbed with dry sawdust. A solution of oxalic acid is used in the same way, smooth surfaces being rubbed with prepared chalk, or equal parts of the latter (or whiting) and oxalic acid, made into a paste with water, may be applied. A great many other processes are employed, such as rubbing with rotten stone and sweet oil, and then with whiting; this is par- ticularly effective with copper articles. III. The following was said to be used by the Prussian soldiery : Sulfuric acid fl.oz. 1 Olive oil fl.oz. 16 Place the oil in an open vessel and add the acid gradually, with constant stirring. IV. Tripoli av.oz. 4 Prepared chalk av.oz. 4 Pumice stone, very fine powder av.oz. 2 Oleic acid fl.oz. 1 Petrolatum, enough to make a soft paste. V. Tripoli Infusorial earth Japan wax Oleic acid Gasoline . av.oz. av.oz. av.oz. .fl.oz. .fl.oz. 2 2 I 2 16 Dissolve the wax and acid in the gasoline, add the powders, and shake well. The tripoli should be gritty enough to scrub well, but fine enough to leave a smooth, unscratched surface. In fact this is the most important ingredient, and any grit that is hard enough to polish well and fine enough to do it without scratching, can be used. Pow- dered quartz, fine pumice, rouge, fine emery, etc., can all or any of them be used, if carefully selected. The func- tion of the infusorial earth is to aid in DOMESTIC UTILITIES. 1051 suspending the grit, and to hinder the evaporation of the benzine, and the lightest and most bulky brands are best. BRICK WALLS, Removing Efflores- ence On. The usual method of treatment for removal of the white efflorescence on brick walls is by painting with dilute muriatic acid. BRONZE PAINTS. The bronze colors as furnished in the pharmacy serve for temporary pur- poses ; that is, they are expected, in ad- dition to drying rapidly to be fairly permanent, but not so much importance is laid upon their resisting moisture and atmospheric influences. Where these latter qualities are de- sired a copal shellac varnish is the best; though the use of any such varn- ish is objectionable because the fatty or resinous acids, either already pres- ent or liable to develop have a chemical action on the copper of the bronze and are apt to cause it to turn green or to deaden the luster of the bronze. The commercial liquid bronzes con- sist for the most part of solutions of resins in turpentine oil and should be rejected on the grounds above indi- cated. Another variety is made of a- mixture of gum dammar, rubber and benzin and this does not present the objectionable features above noted in so marked a degree, but has the dis- advantage that owing to the very rapid evaporation of the benzin it is difficult to work with. The following formulas avoid these objections. The liquid bronze is par- ticularly useful for applying to wicker work, plaster figures, frames, leather, etc. With bronze powder no previous coating with varnish is necessary. The bronze paints are used most in the gold, silver and copper colors. I. Liquid bronze: Bronze powder av.oz. n Borax-shellac solution fl.oz. 5 Alcohol t s , , ."fl.oz. 2 Rub the powder, adding the liquid very slowly; put in (bottles holding about 1 ounce with not too narrow mouths and label with the following directions : Shake before using until the contents are thoroughly mixed. Then apply with a camel's hair pencil, shaking again each time before dipping the pencil in. The borax-shellac solution is made by heating together on a water-bath at a temperature not over 6o° C. a mix- ture of l / 2 av. ounce of powdered borax, 3 av. ounces of orange shellac, and 20 fluidounces of water, stirring frequent- ly, until the shellac is dissolved. II. Weather-proof bronzing powder: Bronze powder av.oz. 13 Dextrin av.oz. 8 Potassium bichromate gr. 10 Powder the bichromate very fine and mix thoroughly with the other powders. III. Bronze powder, not weather proof: Bronze powder av.oz. 3 Dextrin . . 3 av.oz. 1 Dispense in paper parcels of about 150 grains each with the following di- rections : Mix the contents of this package with 2 teaspoonfuls of water, set aside until no lumps are left, and then apply with a camel's hair brush. IV. Bronze paint for cheaper work may be prepared by mixing chrome green, 2 av. pounds; ivory black, 1 av. ounce; chrome yellow, 1 av. ounce; japan, 4 av. ounces. Grind together and thin with linseed oil. V. Another formula is as follows : Prepare a size consisting of ben- zoin, 50 grains; shellac, 1 av. ounce; alcohol, 4 fluidounces. After dissolving by means of a gentle heat, set aside in a cool place for several days and decant the clear solution. To this size the bronze powder is added in sufficient quantity. This paint is applied with a soft brush to the clean metallic sur- face, a second coat being- given if desirable. Apply varnish over all. 1052 THE STANDARD FORMULARY Sometimes the metal is first ground- ed by painting an orange or scarlet color. VI. The following bronzing liquid is quite different from any of the pre- ceding : Red aniline av.oz. I Violet aniline av.oz. i Benzoic acid av.oz. I Alcohol fl.oz. 18 Dissolve the anilines in the alcohol, in a bottle, by the aid of a water bath, add the acid, then boil the mixture on the water bath for 5 or 10 minutes until the greenish color of the liquid has changed to a light brownish bronze. This may be applied to leather, wood, metal, and other surfaces. Another formula mentions 2 ounces of red aniline. BBONZING OF GUN BARRELS. The gun barrels are to be cleaned thoroughly and polished after which one of these solutions is to be applied with a sponge : I. Copper sulfate av.oz. 2^4 Nitric acid fl.oz. 2 Tincture of iron chlorid fl.oz. 3 Solution of antimony chlorid fl.oz. 6 Distilled water fl.oz. 5 Mix and dissolve. II. Iron chlorid av.oz. 2 Gallic acid av.oz. 1 Solution of antimony chlorid fl.oz. i l /2 Distilled water fl.oz. 4 Mix and dissolve. III. Copper sulfate av.oz. 2]/ 2 Nitric acid, commercial fl.oz. 2 Solution of antimony chlorid fl.dr. 3 Solution of iron chlorid fl.dr. 6 Water fl.oz. 5 Mix and dissolve. BROWNING OF, GUN BARRELS. I. A. Solution of iron chlorid. . .fl.oz. \ l / 2 Corrosive sublimate dr. 3 Copper sulfate dr. 3 Fuming nitric acid fl.dr. 2 Distilled water... Mix and dissolve. .fl.oz. 10 B. Potassium sulfid gr. 50 Distilled water..., fl.oz. 10 Mix and dissolve. Clean off the gun barrel with emery paper, then by means of a sponge or soft brush, apply solution A, subse- quently drying in a cool place, so that it may occur rather slowly. Repeat this application and drying twice, or often- er if necessary to secure the shade of stain desired, rubbing over thoroughly before each application with a scratch brush. When the metal is stained deeply enough, lay the barrel in solu- tion B for 20 or 30 minutes, then wash with warm water, and finally with soap water. Then dry and rub over with linseed oil varnish. Better results will be attained by stoppering closely the gun barrel at both ends by means of corks, and lay- ing for at least 30 minutes in each of the baths, which have previously been warmed. — D. II. A. Fuming nitric acid fl.dr. 2^2 Distilled water fl.oz. 16 B. Silver nitrate gr. 80 Distilled water fl.oz. 16 Rub off the gun barrel with emery paper, then by means of a sponge or soft brush apply solution A, dry in a cool place, and rub off with a cloth. Repeat this application, drying and rub- bing off until a handsome oxidized sur- face is produced. Then apply solution B repeatedly, with subsequent exposure to light, until the gun barrel is dark enough, and anoint finally with linseed oil varnish. — D. III. Copper sulfate av.oz. 1 Corrosive sublimate dr. 6 Sweet spirit of nitre fl.oz. 1 Distilled water fl.oz. 15 Rub up first the spirit of nitre with the corrosive sublimate, then add the other ingredients, let it stand in a well- ■ DOMESTIC UTILITIES. 1053 closed bottle in a warm place for 12 hours, and then add the water. Clean and polish the barrel with emery paper, wash it off with lime water, dry, and apply this mixture uniformly. Allow to dry for 24 hours, brush with a scratch brush and wash off. After repeating this three times polish the barrel with leather moistened with olive oil mixed with some oil of turpentine, dry for 12 hours, and finally polish with oil. IV. Solution antimony chlorid. . .fl.oz. 3 Butter av.oz. 4 Olive oil fl.dr. 1 Heat the mixture in a flask and then brush it uniformly over a barrel, previ- ously cleansed and polished; hold the barrel over a moderate coal fire, when a beautiful brown will soon make its ap- pearance ; then polish with olive oil and finally give it a light coat of good amber lacquer mixed with some shellac. V. The United States Ordnance Manual gives a process as follows : Alcohol, 1^2 ounces; sweet spirit of nitre, i]/ 2 ounces; copper sulfate, 1 ounce ; nitric acid, ^4 ounce. Mix and dissolve in 1 quart of warm water and keep it in a glass jar. Clean the barrel well with a solution of caustic soda, to remove grease or oil. Then clean the surface of all stains or marks by emery paper or cloth, so as to produce an even, bright surface for the acid to act upon, and one without finger marks. Stop the bore and vent with wooden plugs. Then apply the mixture to every part with a sponge or rag and expose to the air for 24 hours, when the loose rust should be rubbed off with a steel scratch brush. Use the mixture and the scratch brush twice, and more if necessary, and finally wash in boiling water, dry quickly and wipe with lin- seed oil or varnish with shellac. BUFFALO MOTHS, To Exterminate. This insect which is generally spoken of as the "buffalo moth," "carpet bee- tle," and "carpet bug," is in reality not a moth, but a beetle belonging to the order coleoptera, while true moths, such as the ordinary clothes moths, belong to the order lepidoptera. Tobacco, pepper, camphor, carbolic acid and oil of turpentine have all been recommended for destroying or driving them off, but none of these remedies seem to be of much avail. It is the larva of the insect that works the damage to woolens. When in this condition it is about 3/16 inch long, and is covered by a shaggy coat of black hair, from which the term buffajo moth probably originated. It eventually develops into a beetle about an Y& inch in length, and marked with black, scarlet and white. Benzine, kerosene and good insect powder appear to be the most efficacious substances with which to combat this pest. Carpets which are infested may be soaked in gasoline which if of good quality will leave no odor or stain. When the carpets are taken up it is a good plan to pack all the cracks in the floor with cotton, which should then be saturated with gasoline. When the larvae are found to be injuring furs or clothes hung in the closet, it would be best to use insect powder. It is stated that the insects in car- pets can be destroyed by laying a wet sheet on top of the carpet and passing hot flat-irons over it, the steam thus produced destroying the grub. In rec- ommending the employment of gasoline the dangerously inflammable nature of the liquid should always be called to the attention of the user and the neces- sary precautions suggested. The late Dr. Riley of the Department of Agri- culture recommended this treatment : Bare as many rooms as possible at house-cleaning time, and, after carefully removing all dust, spray benzine by means of an atomizer into all of the floor cracks and under the baseboards until every crevice has been reached. The carpets, after thorough beating, 1054 THE STANDARD FORMULARY should be slightly sprayed in the same manner. Benzine quickly evaporates and leaves no odor. Another method of extermination which has been recommended is fumi- gation with formaldehyde. CALCIMINE, To Prepare. See Kalsomine. CARBOLIZED PAPER. See Paper, Carbolized. CARBON PAPER. See Paper, Carbon or Manifold. CARPET BEETLES, To Extermi- nate. See Buffalo Moths. CARPET CLEANERS. Use any of the preparations men- tioned under Cleansing Creams or Soap, Ox-Gall, or any of the below-mentioned preparations. About the most satisfac- tory carpet cleaners are those which are of a saponaceous character. Liquids. I. Bradford's mixture: Ammonia water fl.oz. 2 Soap solution fl.oz. 4 Gasoline fl.oz. 4 Chloroform fl.dr. 5 Potassium nitrate fl.dr. 2Y2 Oil of wintergreen fl.dr. 2^ Water, to make fl.oz. 32 Some kind of soft water must be used. Mix the ammonia and soap solu- tion, add the gasoline, chloroform, and oil, and then the potassium nitrate dis- solved in the water. This makes a milky mixture which separates somewhat on standing but unites readily upon shaking. The oil of wintergreen may be re- placed by sassafras or other essential oil or it may be omitted altogether. The soap solution may be made by mixing 1 fluidounce of olive (or other fixed oil like cottonseed oil) with 4 fluidrams of alcohol and i l / 2 drams of caustic potash dissolved in 4 fluidrams of water, heating on a water bath until the oil is entirely saponified, which may be shown by adding a drop to boiling water when it should dissolve without any oily separation. Allow the mixture to cool, add 8 fluidounces of alcohol and enough water to make 16 fluidounces, and then filter. Ordinary wood alcohol or the purified kind may be used in- stead of alcohol. II. This is called Clark's wash for carpets : Apply first a mixture of 4 parts of ammonia water and 3 of alco- hol, which is said to loosen the dirt. Then go over the carpet with a mixture composed of Soap av.oz. 2 Water fl.oz. 40 Sal soda av.oz. 7 Ammonia waier fl.oz. 1 Alcohol fl.oz. 1 This removes the dirt without requir- ing removal of the carpet from the floor. Powder. III. Sal soda av.oz. 8 Borax av oz. 4 Both should be in powder. In using, this amount of material is to be dissolved in a gallon of water, then mix this with a solution of a pound of soap (any good washing soap) in 4 gallons of water. Apply this combina- tion, preferably warm, to the carpet with a scrubbing brush, remove the lather with a wooden scraper, and dry the car- pet with a flannel cloth. Soap. IV. Sodium carbonate, powder. av.oz. 16 Fuller's earth av.oz. 8 Oil of turpentine fl.oz. 2 Soft soap, enough to make a paste. This may be dispensed in small wood- en boxes or tin cans. It is used like No. Ill, first dissolving in a sufficiency of water. CARRIAGE-TOP DRESSING. These dressings are to be applied to the enameled tops of carriages. I. Mix 1 av. ounce of India rubber, cut into shreds, with 8 fluidounces of oil of turpentine, macerate in a wide- mouthed bottle or suitable jar for 2 days without agitation, then stir with a DOMESTIC UTILITIES. 1055 ...av.oz. 3 . . . av 0.7. i ...av.oz. J / ...av.oz. 2 wooden paddle. Add another 8 fluid- ounces of oil of turpentine and stir fre- quently until solution is complete. Let stand for a day or two, then decant 12 ounces of the solution, and add 16 fluid- ounces of the best white copal, varnish, and mix thoroughly. Finally add 12 fluidounces of boiled linseed oil, and heat^the whole over a sand-bath, with frequent stirring, until homogeneous. This is said to be the formula of the enameled leather dressing of Champag- nat. II. Shellac Rosin Castile soap, shaved Venice turpentine . . Rosin oil fl.dr. 2 Alcohol fl.oz. 20 Nigrosin dr. 3 Mix all the ingredients, except the nigrosin, heat them cautiously over a water bath until nearly all dissolved, then add the nigrosin, and continue the heat until it is dissolved. CATERPILLAR LIME. This composition is to be smeared on vines or plants to catch caterpillars and prevent them from doing further injury. I. Paraffin wax gr. 75 Linseed oil fl.oz. 5 Venice turpentine av.oz. 6 Mix by melting. II. Pine tar av.oz. 9 Venice turpentine av.oz. 1 Mix by melting. CEMENTS of All Kinds. Some of these are frequently entitled "glues" and possibly . some of the for- mulas to be found under Glues, Liquid, will serve the purpose of a cement. AaUARIUM CEMENTS. I. This preparation is very highly recommended : Litharge parts 3 Plaster of Paris parts 3 White sand parts 3 Rosin part 1 The ingredients should be in fine pow- der and should be made, when wanted for use, into a thick paste with boiled linseed oil to which a little drier has been added. The cement cannot be used after it has been mixed for a few hours. It will serve for fresh water and marine aquaria equally well. It is best to let it harden a day or two before using the aquarium. II. This formula, also an excellent one, is very similar to the preceding : Whiting parts 6 Plaster of Paris parts 3 Fine white sand parts 3 Litharge parts 3 Rosin, powder .part 1 All parts are by measure. Mix the ingredients thoroughly, then make into a putty-like mass with the best coach var- nish. Only enough for one glass should be made up at once, as the material har- dens very quickly. In putting in the glass, first scrape away the embedding material first used, then put on a layer of this cement. As soon as the embed- ding is made, place the glass in, and with a firm, slow pressure push it in, leaving a layer of the cement about 1/16 inch deep underneath the edges. Fasten the glass to place with brads and imme- diately put on the outside, cementing ex- actly like putty. If the woodwork is new it is best to go around the edges of the glass and the wood next it with a- light layer of coach varnish, applying the "putty" immediately thereafter. Let the apparatus stand for 5 or 6 days to harden, then cover the putty outside and inside with two coats of asphalt varnish, carrying the varnish well over on the glass. III. Plaster of Paris parts 2 Marble dust parts 2 Litharge parts 2 Rosin, powder part 1 All parts are by measure. Mix the powders and make into a putty, just be- fore using, with boiled linseed oil. The details of using are the same as with No. II. 1056 THE STANDARD FORMULARY Bicycle Tire Cement. See also Puncture Cement. IV. Gutta percha av.oz. y 2 Caoutchouc av.oz. I Carbon disulfid . . . .' fl.oz. 8 Mix and dissolve. This cement is dropped into the crev- ices after they have been properly clean- ed. If the rent is very big apply the ce- ment in layers. Bind up the rubber tire lightly with thread, let dry for 24 to 36 hours, cut off the thread and remove the protruding cement with a sharp knife, which must previously have been dipped in water. V. Caoutchouc av.oz. 6^ Resin av.oz. 1 Shellac av.oz. 94 Carbon disulfid, enough to dis- solve the other ingredients. Use like No. IV. Casein Cement. Casein when made into a cement makes a good adhesive for uniting pa- per, cloth, leather, crockery, etc. There are various methods for making such a cement. Freshly precipitated, washed and drained casein is meant in each in- stance. VI. Borax part 1 Water parts 19 Casein sufficient Dissolve the borax in the water and add enough fresh casein to make a prep- aration of about the consistence of honey, stirring vigorously to effect solu- tion.— D. VII. This is better adapted for mending crockery, glassware, porcelain, etc. Casein, fresh, any desired quantity. Solution of sodium silicate, sufficient. Triturate the casein in a mortar with enough of the solution to make a honey- like mixture. This will keep for some time in well- closed wide-mouthed bottles. It is a transparent cement but does not resist the action of water.— D. Cement for Crockery, Porcelain, Glassware, Etc. Any number of formulas under the general heading of Cements are adapted to the purpose of mending crockery, porcelain, glassware and similar sub- stances, such as some of the Casein Ce- ments, Chromium Cement, Diamond Ce- ment, and others. Here are some others. An almost invisible joint may be made, with careful handling, with the follow- ing: VIII. India-rubber parts 5 Mastic parts 3 Chloroform parts 12 Cut the rubber into shreds, put into a suitable vial, and pour on the chloro- form. Stopper tightly, and set aside un- til the rubber is dissolved, then add the mastic, and let stand until it is dissolved. Apply the cement to each surface to be united, and let the pieces stand until the greater part of the chloroform is evapo- rated, then unite, press firmly to place, and if possible tie in position. When the cement is apparently thoroughly dry on the surface, scrape off the superfluity, and dust over the line of junction a lit- tle zinc oxid, chalk, or some such ma- terial, and with a clean pencil brush it over the joint. After the cement has become perfectly dry, remove the cords and rub off the superfluous powder. Cement for Celluloid. IX. It is stated that if the edges of pieces of celluloid be moistened with glacial acetic acid, they may be fastened together. The parts should be held to- gether with pieces of twine until thor- oughly dried. Dental Cements. There are so many of these cements that they are merely referred to here. X. Sorel's cement for filling cavities in teeth is made by adding rapidly, deli- quescent zinc chlorid to enough zinc oxid to make a thick paste, and applying it immediately. Zinc phosphate cement is made by DOMESTIC UTILITIES. 1057 mixing zinc oxid with syrupy phosphoric acid. Diamond or Armenian Cement. XI. This preparation is an old-fash- ioned but exceedingly good article which is almost a universal cement, as it will stick together the most diverse articles. The formulas differ somewhat from each other. Isinglass (fish glue) av.oz. I Gum mastic dr. 4 Gum ammoniac or galbanum. .dr. 2 Alcohol fl.oz. 8 Water fl.oz. 8 Soak the isinglass in the water for 24 hours, evaporate on a water bath to 4 fluidounces, add 4 fluidounces of alcohol, strain, add the mastic dissolved in the remaining alcohol, and add the ammonia or galbanum by trituration, avoiding loss of alcohol as much as possible. This cement must be warmed gently in a water-bath before use. XII. A slight modification, which is an improvement, is this : Isinglass (fish glue) .av.oz. I Gum ammoniac gr. 36 Gum mastic gr. 18 Alcohol, 95% fl.dr. iY 2 Water, sufficient. Soak the isinglass in cold water for a few hours or over night, until it has swollen and become soft throughout. Then pour off the superfluous water and drain the magma on a towel. Upon the thoroughness of this will depend in a great measure the strength of the ce- ment. Then transfer the gelatin to a water-bath and heat until it becomes fluid. Dissolve the gums in the alcohol and add the solution to the gelatin liquid after the latter has been allowed to cool to about 160 F., stir the whole well or mix by agitation. Cement for Gas Burners. XIII. Litharge, glycerin, each suffi- cient to make a stiff paste. For Cementing Glassware. Use any of the preparations mentioned under "cements for crockery, etc.," "chromium cement," or "diamond ce- ment." The liquid glues are also suitable for mending glassware which does not come in contact with liquids. See Glues, Li- quid. For Cementing Glass Labels to Bottles. XV. Rosin part 1 Yellow wax parts 2 Melt together, allow to cool somewhat, but apply in the melted condition. In using, apply a plentiful amount of the composition, draw a line around the edges of the label, and when the mix- ture has hardened the excess which has exuded around the label mav be scraped off. XVI. A thick mixture of white lead and varnish is also good for this pur- pose. The cement requires longer to dry than No. XV. Gutta Percha Cement. XVII. Gutta percha, in pieces av.oz. 2 Asphalt, powder av.oz. 2 Carbon disulfid fl.oz. 4 Oil of turpentine fl.oz. 1 Dissolve the gutta percha in the car- bon disulfid and oil, add the asphalt and let stand for several days, when it will be ready for use. This is used for mending leather, ce- menting leather upon wood, etc. Before using upon leather, the latter must be freed from fat by treatment with ben- zin. — D. See also the rubber cements. Cement for Iron. XVIII. Sulfur av.oz. 6 White lead av.oz. 6 Borax av.oz. 1 Mix well and make into a paste with sulfuric acid. Apply cement to the parts, using pres- sure and allowing to stand for 5 to 7 hours. Leather Cements. XIX. Cements for leather vary ac- 1058 THE STANDARD FORMULARY cording to the material to which the leather is to be attached — whether leath- er to wood, or to metals, or to another piece of leather. For the first, any good gelatin cement will answer. One of the best formulas, which also acts as a gen- eral cement for household purposes, is as follows : Soak gelatin in cold water over night. In the morning pour off any water that may remain unabsorbed, throw the gelatin on a towel and press off any superfluous water; then put it in a water-bath and heat until melted. Re- move from the fire, and carefully add sufficient acetic acid to keep the gelatin liquid in moderately warm weather. Ap- ply this plentifully to the leather, and lightly to the wood, join together, and put a weight on to keep in place for a short time. XX. A cement for uniting leather to leather, as in the case of bands and pulleys, is made as follows : Soak ioo parts of best white glue in cold water over night, and treat as in No. XIX as regards draining and heating. When the glue becomes liquid add 2 parts of gly- cerin in which has been stirred 2 parts of powdered potassium bichromate. In- crease the heat until the water in the bath boils, then remove and apply at once. Only as much as is necessary for immediate use should be made at one time, as the mixture becomes insoluble after cooling. This may be avoided by reserving the potassium chromate, and adding it only to the portion to be used just before it is applied. XXI. A cement for leather to leather, in patching shoes, etc., is made by dis- solving gutta percha in a mixture of io parts of carbon disulfid, and I part of oil of turpentine. Cut up the gutta percha as finely as possible, and add it to the mixture until a solution about as thick as molasses is obtained. Keep in a well stoppered bottle, and if the cement gets too thick add a little of the disulfid mixture. To apply this, the edge of the applied patch must be cham- fered down as thinly as possible, and the surface of the shoe leather scraped until it is free from grease, blacking, etc. If the shoes have been oiled the grease must be got rid of by saturat- ing the leather with ether or carbon di- sulfid, and pressing, on blotting paper, or a cloth, with a hot iron. Apply a coating of the cement to each piece (i.e., the patch and the leather to which it is to be joined), leave them for a few moments in order to allow the surplus of solvent to evaporate, then join and press closely together with a hot iron. XXII. To join leather to metals, glass, etc., melt together equal parts of asphaltum and gutta percha, and ap- ply hot. Mending Mortars. XXIII. Broken wedgewood mortars may be united by making a paste of calomel and mucilage of acacia, apply- ing to the broken edges, binding the parts together firmly, and then setting aside for a week or so to "set" firmly. XXIII. Fill a bottle one-fourth full of freshly-precipitated, washed and drained casein, fill the bottle with so- dium silicate solution, and shake occa- sionally, until the casein is dissolved. Use like the preceding. Cement for Pestle Handles. See Pestle Handles, To Cement. Cement for Porcelain, Marble, Ala- baster, Etc. Use any of the casein cements, Dia- mond cement, or any of the cements recommended for mending crockery, glassware or mortars. To Fasten Porcelain Letters to Win- dows. See under Enameled Letters. Puncture Cement. A patented preparation for the auto- matic repairing of punctures in bicycle tires consists of glycerin holding gela- tinous silica or aluminum hydrate in suspension. Three volumes of glycerin are mixed with one volume of liquid DOMESTIC UTILITIES. 1059 water-glass and an acid is stirred in. The resulting jelly is diluted with three additional volumes of glycerin, and from four to six ounces of this fluid are placed in each tire. In case of punc- ture, the internal pressure of the air forces the fluid into the hole, which it closes. Cement or Lute for Retorts, Etc. XXIV. Clay, powdered and sifted, .av.oz. 6 Rve" flour av.oz. 3 Bran av.oz. 1 Mix them well. When wanted, take a sufficient quantity and mix it with water to a dough to be applied to the retort or flask.— D. Rubber Cements. The preparations mentioned under "bicycle tire cements" are nearly all rub- ber cements. Here are some other for- mulas : XXV. Caoutchouc av.oz. 1 Rosin dr. iy 2 Venice turpentine gr. 45 Oil of turpentine fl.oz. 2 Chloroform fl.oz. 14 Mix all and dissolve by agitation. XXVI. Silicate Cement. Glass, powdered av.oz. 1 Fine sand av.oz. 2 Solution of sodium silicate av.oz. 6 Mix together quickly and use at once. This is a good cement for mending sandstone, and is useful in repairing the fronts of houses built of this stone. Any shade of the stone can be obtained by the addition of raw or burnt sienna or umber. It may also be used for mend- ing cracks or chips in mortars and other stoneware. Tire Cement. See Bicycle Tire Cement. Cement for Stoneware, Use any of the cements mentioned as suitable for porcelain, crockery, glass- ware, etc., also Diamond cement, silicate cement, and some of the casein cements. 67 Water-Proof Cement. XXVII. Cement absolutely water and acid-proof may be made by mixing 6 parts of Burgundy pitch, 1 part of shred- ded guta-percha, and 3 parts of pow- dered pumice. Melt the gutta-percha very carefully add the pumice stone, and then the pitch previously melted. This is to be used while hot. It may be used for mending photographic trays, stoneware, woodenware and many other things. See also Glue, Waterproof. WinchelPs Paste or Cement. XXVIII. These are Prof. Winchell's own directions : Take 4 ounces of clear gum arabic, 3 ounces of fine starch and 1 ounce of white sugar. Pulverize the gum arabic, and dissolve it in as much water as the laundress would use for the quantity of starch indicated. Dis- solve the starch and sugar in the gum solution. Then cook in boiling water, until the starch becomes clear. The cement should be as thick as tar, and kept so. It can be kept from spoiling by dropping in a lump of camphor, or a little oil of clove or sassafras. This cement is very strong and will stick to glazed surfaces, and is good to re- pair broken rocks, minerals, or fossils. CHAIR-LEATHER POLISH. See Leather Polish. CHAMOIS SKIN, To Clean. In a suitable vessel. place a weak solu- tion of sodium hydrate and add to this some soap shavings or soap solution. Throw the chamois into this, let soak for two or three hours, and then rub it clean. Rinse in clean tepid suds, wring out, wrap in a cloth and dry quickly. When dry, rub together or brush with a stiff brush, to restore softness. Another method 'highly recommended is to rub the chamois thoroughly with soap, then allow it to remain for 2 hours in a weak, warm solution of sal soda. and rinse until clean. Instead of rins- ing in clean water and removing all traces of soap, rinse in a weak, soapy 1060 THE STANDARD FORMULARY solution of soda, such as was used for washing in the first place. It is the soap left in the leather by the rinsing solution that keeps it soft and smooth. After rinsing, wring out the leather in a coarse towel and dry quickly; then brush well, and pull and rub it thor- oughly in the hands. If this method is followed carefully the leather is said to come out soft and pliable. CHEMICAL, GARDEN. This may be prepared as follows : Place a quantity of sand in a wide- mouthed bottle (or better, a half gallon fish-globe) to the depth of 2 or 3 inches; in this layer of sand, slightly imbed a few pieces of copper sulfate, aluminum sulfate, iron sulfate, chrome- alum, lead acetate, calcium chlorid, and .magnesium and manganese sulfates; pour over the whole a solution of so- dium silicate (commercial water-glass) one part and water three parts, care be- ing taken not to disarrange the chemi- cals in pouring in the solution. Upon standing a week or so, a dense growth of the silicates of the various bases used will be seen in various colors, and fan- tastic shapes. Now displace the solution of the sodium silicate with clear water, by conveying a small stream of water through a small rubber tube (such as nursing bottle tubing) into the ves- sel, which will gradually displace the silicate of soda solution. Care must be taken not to disarrange or break down the growth with the stream of water. When successful, this produces a very beautiful scene. Other sulfates, such as those of chromium, cobalt, nickel, etc., may also be used. The following so-called "metallic trees" are similar to the preceding : For a silver tree, dissolve two ten-cent pieces in 2 fluidrams of concentrated nitric acid, evaporating nearly to dryness to drive off excess of acid, cool, and dis- solve the resulting crystalline salts in sufficient distilled water to make a sat- urated solution. This solution will be slightly blue on account of the copper which is alloyed with coin silver. Place the solution in a glass vessel with a curved bottom. Add a drop of mercury the size of a large pea and set aside for 24 hours or place in the window. An arborescent growth of mercury and silver amalgam will be produced which may be kept indefinitely. To make a lead tree place in a tall jar or wide-mouthed bottle a solution made by dissolving 4 ounces of lead ace- tate in one quart of water. Place the vessel where it will not be subject to vibration, and suspend in it a strip or cylinder of zinc ; battery zinc answers the purpose very well. An abundant growth of crystalline spangles of metal- lic lead will collect on the zinc within 48 hours. To grow a tin tree dilute commercial tin chlorid solution with 40 times its bulk of water and suspend a strip or pencil of zinc in it as in the case of the lead tree. The growth wall be very similar to that of the lead tree. CHIMNEY CLEANERS. A mixture of 2 parts of common salt and 1 part of sulfur has been used for this purpose. A mixture of sal ammoniac and sulfur has also been used for this purpose. See also under heading Stovepipes, To free from Soot. CLEANING COPPER DRAIN BOARDS. See Drain Boards, Copper, To clean. CLEANING GREASY BOTTLES. See Bottles, Cleaning Greasy CLEANSING PREPARATIONS. Under this heading are arranged a number of preparations that are used for removing stains and spots of all kinds, greasy, tarry, and otherwise, from clothing, various kinds of fabrics, car- pets rugs, etc. Other cleansing preparations may be found under the headings Ammonia. Household ; Benzin Jelly ; Carpet Clean- ers ; Glove Cleaners ; Stains from Fab- rics, To Remove; and Soap, Ox-Gall. DOMESTIC UTILITIES. 1061 Creams. Under this heading are mentioned those preparations which are of a sapon- aceous character. Various names are used for these preparations, such as Electric Cleansing Compound, Lightning Renovator, Jap- anese Cleansing Cream, Excelsior Clean- ing Fluid, Erasine, Detergent Cream, Universal Cleanser, Magic Clothes Cleaner, etc. The following would be suitable di- rections for these preparations : To remove grease-spots from clothes. — Spread the part with the stains upon a table, putting a folded towel below the spots ; rub in the sream in a circular direction by means of a sponge, then rinse in clear water. To brighten black clothes.— Sponge the whole of the garment equally with the cream, first having removed any stains as above directed. Then hang out in the open air to dry, and iron if neces- sary. To renovate carpets. — After thorough- ly switching the carpet, or relaying after beating, take a stiff brush, such as a fibre scrubbing brush, and apply the cream over the whole surface, rubbing the stained parts hard. Finish off with a damp washing cloth. To clean flannels. — A teacupful of the cream to be mixed with 10 gallons of water. In this mixture steep the flannels all night, and it will be found that they wash with ease next morning. For cleaning paint. — Add a teacupful to a pailful of lukewarm water. To clean windows. — Mix i part of the cream with 5 parts of plain water. Wood or denatured alcohol may be substituted for ordinary alcohol in mak- ing these mixtures. I. Stronger ammonia water, .fl. dr. 4 Castile soap, white av.oz. 2 Glycerin fl.oz. 2 Ether fl.oz. 2 Water, to make fl.oz. 64 To 32 fluidounces of water add the glycerin, ether and ammonia, Shake well, add the soap in fine shaving and the remainder of the water, and shake often until the soap is dissolved. II. Castile soap av.oz. 1 Ether fl.oz. 1 Alcohol fl.oz. 1 Glycerin fl.oz. 1 Ammonia water fl.oz. 4 Oil of wintergreen fl.dr. 1 Water, distilled, to make. . .fl.oz. 64 Dissolve the soap in the water by the aid of heat, add the oil dissolved in the alcohol and ether, and incorpor- ate the other ingredients. III. Castile soap av.oz. 1 y 2 Alcohol fl.oz. iy 2 Ether _ fl.oz. 1% Glycerin fl.oz. 1 Ammonia water fl.oz. 3 Oil of citronella or mirbane drops 5 Water, to make fl.oz. 64 Prepare like either of the preceding. IV. Soft (green) soap av.oz. 2 Potassium carbonate. .... .av.oz. r / 2 Ammonia water fl.oz. 4 Water, to make fl.oz. 64 Liquids. These are used for the same purposes as the creams. These contain such in- gredients as ether, chloroform, gasoline, ammonia water, oil of turpentine, etc. Preparations containing any consider- able proportion of gasoline, benzine or ether must be handled very carefully to avoid proximity to any fires or arti- ficial lights. V. Chloroform fl.oz. 4 Ether fl.oz. 1 Oil of bergamot fl.dr. 2 Gasoline, to make fl.oz. 32 VI. Alcohol fl.dr. 5 Chloroform fl.dr. 5 Oil of sassafras fl.dr, 5 Gasoline or benzin il.o; . 32 VTI. Ether fl.dr. 1 Chloroform fl.dr. 1 1062 THE STANDARD FORMULARY Ammonia water fl.dr. I Oil of wintergreen fl.dr. i Alcohol fl.oz. i Gasoline, to make fl.oz. 32 VIII. Tincture of green soap. .. .fl.oz. 2 Alcohol fl.oz. 8 Ammonia water fl.oz. 16 Water, to make fl.oz. 64 Powders. Formulas for powders for cleaning gloves and fabrics may be found under the heading Glove Cleaners. Soaps. See also the heading Soap, O-Gall, and Benzin Jelly, also the soaps under Carpet Cleaners. In using the soap may be applied to the spot, then rinse the fabric in clean water. IX. Cocoanut-oil soap av.oz. 16 Fuller's earth av.oz. 8 Water sufficient Melt the soap with the smallest amount of water by the aid of heat, and incorporate the fuller's earth. This may be perfumed if desired. It may be put up in cakes wrapped in tin foil or a parchment paper or in small cans. X. Soap, in shavings av.oz. 15 Potassium carbonate av.oz. 3 Oil of turpentine fl.oz. 2 Water sufficient Dissolve the soap and potassium car- bonate in the smallest amount of water by the aid of heat, then incorporate the oil. This is best dispensed in cans. XI. Soft soap av.lb. 3 Oil of turpentine fl.oz. 16 Melt the soap at a gentle heat, remove from the fire, and incorporate with the "oil gradually added. This is useful for removing stains, tar, grease, etc., from the hands. Rub the hands with a small piece, then wash with water. This will also remove the objectionable odor of iodoform. CLOTH-CLEANING COMPOUNDS. See under headings Benzin Jelly ; Am- monia, Household; Cleansing Prepara- tions; Glove Cleaners; Soap, Ox-Gall; and Stains from Fabrics, To Remove. COCKROACH DESTROYERS. See Roach Exterminators. COLORED FIRES. See Fires, Colored. COLORING ELECTRIC LIGHT GLOBES. See Electric Light Globes, To Color. COLORING OF METALS. See under the following headings : Bluing of Gun Barrels; Bronzing of Gun Barrels ; Browning of Gun Bar- rels ; Copper, Bluing of ; Copper, Brown- ing of; Silver, "Oxidizing" of; and Zinc, Coloring. COPPER, BLUING OF. Dissolve 1 part of Schlippe's salt in 15 of water, heat to boiling in a porce- lain or porcelain-lined vessel, then intro- duce the copper, suspending the latter so it does not touch the sides of the ves- sel, allow it to remain until sufficiently affected, then remove, wash and dry. — H. COPPER, Browning of. I. Cleanse the copper thoroughly with emery paper, heat over a coal fire, then apply this solution: Copper acetate dr. 6 Ammonia chlorid dr. 8^2 Acetic acid, 30% dr. 4 Distilled water fl.oz. 13^ Allow to dry and finally polish with a mixture of 1 part of wax arid 4 of oil of turpentine. — D. II. Ebermayer's process is this : Ammonium carbonate dr. 6 Copper acetate dr. 3 Ammonium chlorid gr. 72 Oxalic acid gr. 18 Vinegar fl.oz. 16 Dissolve the ammonium carbonate and copper acetate in 4 fluidounces of vine- gar, evaporate this to one-half its vol- ume, add the ammonium chlorid and oxalic acid, previously dissolved in the remainder of the vinegar, heat the whole mixture, allow it to cool, and then filter. Clean the medallion or other copper article, and boil in the prepared mix- DOMESTIC UTILITIES. 1063 ture until it is covered with a yellowish- brown coating. COPPER PLATING. See Plating with Gold, Silver, Tin, etc. COPPER. POLISHES FOR. See Brass, Polishes for, which will serve as well for copper. COPPER DRAIN BOARDS, TO CLEAN. See Drain Boards, Copper, To Clean. COPYING PADS. See Hectograph Masses. COPYING PAPER. See Paper, Carbon. CORKS, IMPERVIOUS AND ACID- PROOF. The most common method of render- ing corks impervious and acid-proof is to immerse them in melted paraffin. The following process leaves them supple while making them acid-proof and im- pervious : Plunge the corks into a so- lution of gelatin or common glue, 15 parts, in 24 parts of glycerin and 500 parts of water, heated to 44 or 48 C, and keep them there for several hours. On removing the corks, which should be weighted down in the solution, dry them in the shade until they are free from all surplus moisture. They are now perfectly tight, retaining at the same time the greater portion of their elasticity and suppleness. To render them acid-proof, they should now be treated in a mixture of petrolatum, 2 parts, and paraffin, 7 parts, heated to about 40 C. This second operation may be avoided by adding to the gelatin solution a little ammonium or potassium dichromate and afterwards exposing the corks to the light. A patented process brought out some years ago consisted in immersing corks in a solution of caoutchouc, 1, in ben- zol, 19, drying the corks thus treated in a vacuum, and freeing from odor by exposure to air. Another patented method of treating corks is to soak in a solution of casein . . .av.oz. 4 . . .av.oz. 2 . . .av.oz. 1 and then in formaldehyde solution, which latter hardens the casein. COUNTERFEIT COIN DETECTOR. Silver nitrate gr. 24 Nitric acid, pure drops 15 Distilled water fl.oz. 1 Mix and dissolve. Apply a drop to the suspected coin by means of a glass rod. If any other metal than silver is present in larger quantities than the standard United States alloy, a black spot or stain will be produced en the coin. CRAYONS for Writing on Glass. These crayons are intended for writ- ing on glass, porcelain and metal. Black. Lampblack av.oz. 1 Wax av.oz. 4 Talcum av.oz. 1 White. Zinc oxid Wax Talcum Blue. Prussian blue av.oz. 1^ Wax av.oz. 2 Talcum av.oz. 1 Red. Vermilion av.oz. 2 Wax av.oz. 2 Talcum av.oz. 2 Yellow. Chrome yellow av.oz. 1 Wax av.oz. 2 Talcum av.oz. 2 The colors are incorporated with the molten wax, the talcum added and the whole rubbed together until cold. The mass is then formed into pencils by means of a hydraulic press. If these crayons are intended for writing on bottles, the mass may be rolled out like a pill-pipe into pencils of the thickness of a lead pencil. CROCUS MARTES. See Jeweler's Rouge. CROTON BUG EXTERMINATORS. The same remedies may be employed for the extermination of croton bugs as are employed against roaches. See Roach Exterminators. 1064 THE STANDARD FORMULARY CUTTING OF GLASS, Bottles, Etc. See Glass, Cutting of. DANCE-HALL POWDER. See Floor Wax in Powder. DENATURED ALCOHOL. There are at present two general for- mulas for denatured alcohol in use, eith- er one of which may be used by any manufacturer who can use denatured alcohol. The first and most common one is made up as follows: Formula No. I. Ethyl alcohol gall, ioo Methyl alcohol gall. 10 Benzine gall. Vz Where such a formula as this is re- quired in an aqueous solution the ben- zine is of course thrown out, giving the solution a milky appearance. In this case the other general formula may be used. Formula Xo. 2. Ethyl alcohol gall. 100 Methyl alcohol gall. 2 Pyridine bases gall. y 2 Whenever generally denatured alcohol is ordered, Formula Xo. 1 will be ship- ped unless Formula Xo. 2 is specially ordered. In addition to these two general for- mulas for denatured alcohol a number of special formulas have been author- ized to be used in the manufacture of certain classes of goods. In order to buy these specially denatured alcohols it is necessary to obtain a permit first from the Collector of Internal Revenue, as a simple permit to use denatured al- cohol will not suffice. Some of the spe- cial formulas are as follows : Formula Xo. 3. For the manufacture of celluloid, py- ralin and similar products. Ethyl alcohol gall. 100 Methyl alcohol gall. 5 Camphor lb. 7 Formula Xo. 4. For use in the manufacture of trans- parent soap. Ethyl alcohol gall. 100 Methyl alcohol gall. 5 Castor oil gall. 1 36 B. caustic soda solution. gall. V2 Formula Xo. 5. For the manufacture of shellac var- nish. Ethyl alcohol gall. 100 Methyl alcohol gall. 5 Formula No. 6. For the manufacture of smoking and chewing tobacco. Ethyl alcohol gall. 100 A mixture made as follows ; Aqueous solution containing 40% nicotine gall. 12 Acid yellow dye lb. 4/10 Tetrazo brilliant blue 12 B Conct. lb. 4/10 Water, to make gall. 100 Formula Xo. 7. For the manufacture of photo-engrav- ings. Ethyl alcohol gall. 100 Sulfuric ether lb. 65 Cadmium iodid lb. 3 Ammonium iodid lb. 3 Formula N'o. 8. For the manufacture of fulminate of mercury. Ethyl alcohol gall. 100 Methyl alcohol gall. 3 Pyridine bases gall. l /i DENATURED OLIVE OIL. Olive oil may be imported into this country free of duty for use for me- chanical or manufacturing purposes on the addition to each 100 gallons of the oil any of the following substances : 1. 3 gallons of rosin oil, preferably second or third runs. 2. 3 gallons of refined destructively distilled wood turpentine, boiling not lower than ioo C. 3. 3 gallons of mineral oil, such as spindle oil, or a rather crude kerosene. 4. J4 gallon of pyridine. 5. V2 gallon of creosote. 6. 1 gallon of aniline oil. 7. 3 gallons of dark-colored oleic acid. 8. 16 ounces of oil of rosemary. 9. 6 ounces of oleoresin of capsicum. DOMESTIC UTILITIES. 1065 Oil denatured according to 2, 4, 5 and 6 must be marked "poison." (From the regulations of the Secre- tary of the Treasury, 1909.) DENTISTS' AMALGAM FILLINGS. The exact composition of these fill- ings is kept secret, but they are supposed to contain among other things mercury, gold, platinum, etc. The following for- mula may be used: Tin, fine raspings parts 31 Silver, fine raspings parts 19 Mercury parts 25 Mix, heat gently until dissolved, allow to cool, and press through chamois leather. Another formula is the following: Fletcher's platin-gold amalgam. Platinum parts 1.30 Gold parts 3.35 Silver parts 43.35 Copper parts 1.65 Tin parts 50.35 Another formula is this: Telchow's gold amalgam. Gold parts 4.18 Silver parts 55.00 Tin parts 40.00 DENTAL ANTISEPTIC. The following preparation, known as Howard's antiseptic, is used for render- ing the tooth cavities and root canals antiseptic in dental work : Carbolic acid dr. 4 Oil of cassia fl.dr. 1 Oil of clove fl.dr. 1 Thymol dr. 2 Glycerin fl.dr. 1 Tannic acid gr. 20 The cavities are saturated with the so- lution, then lightly packed with absorb- ent cotton dipped in the liquid, and final- ly sealed with a piece of cotton-wool saturated with sandarac varnish. DENTISTS' ARSENIC PASTE or Nerve Destroyer. I. Arsenous acid parts 2 Morphine sulfate part 1 Creosote, enough to form a stiff paste. This is used by dentists to destroy dental nerves so as to permit the filling of carious teeth. It should be used only under the direct supervision of a den- tist. II. Arsenous acid, Morphine hydrochlorid, equal parts of each. Liquefied carbolic acid, enough to form a paste. Cocaine hydrochlorid, 5%. DENTISTS' MOLDING WAX. Ordinary impression wax may be made by tempering paraffin wax with olive oil. This may be colored with rose pink or armenian bole. Here are other formulas : I. Resin av.oz. 2 Olive oil fl.oz. 4 Hard paraffin av.oz. 6 Rose pink sufficient Melt the resin and paraffin and mix with the oil and coloring, stir constantly until cool. The amount of oil may be increased or decreased according to the consistence desired. Liquid petrolatum, cottonseed oil, or other oil may be sub- stituted for the olive oil. II. Stearin av.oz. 3 Copal resin av.oz. 3 Talcum, powder av.oz. 6 Carmine, powder gr. 15 Oil of rose geranium drops 20 Melt the copal by the heat of a sand bath, add the stearin, mix, remove from the fire, add the other ingredients and stir to produce a homogeneous mixture. III. Gum mastic av.oz. 2 Castor oil fl.oz. 1^2 Yellow wax av.oz. 10 DEVELOPERS for Photographs. Pure chemicals and distilled water only must be used in preparing theSe liquids. I. Metol gr. 48 Hydrochinone gr. 48 Sodium sulfite, dried gr. 375 Sodium carbonate, dried gr. 24O Distilled water, to make... fl.oz. 16 Dissolve the sodium sulfite in a por- tion of the water and filter the liquid if not clear; then add the hydrochinone and sodium carbonate, dissolve by agi- 1066 THE STANDARD FORMULARY tation, add the metol last, and then the remainder of the water. Most developers contain too much sul- fite and when used the negative fogs be- fore it is sufficiently developed. This solution is never to be used if it has become milky. This developer may be used with sat- isfaction for all kinds of paper and plates. It works better on paper if a few drops of a 10% solution of potas- sium bromid are added to it. For plates this solution should not be stronger than Vz or even sometimes y$. II. Hauff's formula for separated de- veloper : Solution A. Metol gr. 75 Sodium sulfite, crystal av.oz. i% Distilled water fl.oz. 10 Dissolve the metol completely in the water before adding the sulfite. Solution B. Potassium bromid gr. 8 Sodium carbonate av.oz. i}i Distilled water fl.oz. io For most purposes, equal parts of So- lution A and B are to be mixed; in some cases, equal parts of Solutions A and B and distilled water are used. III. Hauff's One-Solution Developer: Metol gr. 75 Potassium bromid gr. 8 Sodium sulfite, crystal av.oz. 1 54 Sodium carbonate, crystal. av.oz. i$4 Dissolve the metol in the water before adding the other ingredients. For most purposes, mix i part of this liquid with I of water; for some pur- poses, i part is mixed with 2 of water. IV. Capt. Abney recommends the following as a developer for dry plates : Solution A. Potassium citrate gr. 700 Potassium oxalate gr. 200 Distilled water fl.oz. 3^ Solution B. Ferrous sulfate, pure gr. 300 Distilled water fl.oz. y/ 2 For use, mix the two liquids in equal proportions. 'V. Pyrogallic acid gr. 10 Sodium carbonate gr. 75 Sodium sulfiate dr. 2 Distilled water fl.oz. 4 Develop the film or plate with this liquid, then transfer to a fixing bath composed of Sodium hvposulfite av.oz. 2 Water fl.oz. 8 Keep the negative immersed in this liquid until it is clear, then wash in run- ning water for half an hour. DIAMOND DUST. There are two kinds on the market, one being mica which has been split into thin sheets and then powdered. The other kind is powdered glass which may have been prepared by blowing glass into thin bulbs and powdering it. Or the glass may have been heated red hot and dropped into cold water. It may be still further powdered, after which it is to be sifted. The two kinds may be distinguished by the softer feel of the mica. DISINFECTANTS AND DISINFEC- TION. The object of disinfection is to pre- vent the extension of infectious or con- tagious diseases by destroying specific infectious material, commonly known as bacteria, microbes or germs, which give rise to them. This is accomplished by the use of disinfectants. Popularly the term disinfection is used in a much broader sense. Any chemical agent which destroys or masks bad odors, or which arrests putrefactive decomposition is spoken of as a "disin- fectant." And in the absence of any in- fectious disease it is common to speak of "disinfecting" a foul cess-pool, or bad smelling stable, or privy vault. This popular use of the term has led to much misapprehension, and the agents which have been found to destroy bad odors — deodorizers — or to arrest putre- factive decomposition — antiseptics — have been confidently recommended and ex- tensively used for the destruction of dis- DOMESTIC UTILITIES. 1067 ease germs in the excreta of patients with cholera, typhoid fever, etc. The various consequences which are likely to result from such misapprehen- sion and misuse of the word "disinfect- ant" will be appreciated when it is known that many of the agents which have been found useful as deodorizers, or as antiseptics, are entirely without value for the destruction of disease germs. This is true, for example, as re- gards the iron sulfate or copperas, a salt which has been extensively used with the idea that it is a valuable disin- fectant. As a matter of fact, iron sul- fate in saturated solution does not de- stroy the vitality of disease germs or the infecting power of material contain- ing them. This salt is, nevertheless, a very valuable antiseptic, and its low price makes it one of the most available agents for the arrest of putrefactive de- composition in privy vaults, etc. Antiseptic agents also exercise a re- straining influence upon the develop- ment of disease germs, and their use during epidemics is to be recommended, when masses of organic material in the vicinity of human habitations cannot be completely destroyed, or removed or disinfected. While an antiseptic agent is not neces- sarily a disinfectant, all disinfectants are antiseptics, for putrefactive decomposi- tion is due to the development of "germs" of the same class as that to which disease germs belong, and the agents which destroy the latter also de- stroy the bacteria of putrefaction, when brought in contact with them in suffi- cient quantity, or restrain their develop- ment when present in smaller amounts. A large number of the proprietary "disinfectants" so-called, which are in the market, are simply deodorizers or antiseptics, of greater or less value, and are entirely untrustworthy for disinfect- ing purposes. Antiseptics are to be used at all times when it is impracticable to remove filth | from the vicinity of human habitations, but they are a poor substitute for clean- liness. During the prevalence of epidemic diseases, such as yellow fever, cholera, typhoid fever, etc., it is better to use in privy vaults, cess pools, etc., those anti- septics which are also disinfectants — i. e., germicides ; and when the contents of such vessels are known to be infected this becomes imperative. Disease germs exist not only in dejecta, but also in the atmosphere; they may be attached to clothing, the germs of tuberculosis may exist in sputa, etc. In the sick room we have disease germs at a disadvantage, for we know fairly well how to find them as well as how to destroy them. Having this knowledge, our efforts should be direct- ed to restrict the dissemination and propagation of these germs. The disinfectants that are of the most value depend on the immediate object to be accomplished. Experiments have shown that among the most efficient of all true disinfectants must be ranked corrosive sublimate. But this is poison- ous also to the higher animals, and can- not, therefore, have universal applica- tion. For disinfecting excrementitious products, it must be considered the best agent there is, and it can be employed also in treating articles of clothing, etc., which should also be boiled before they are again used. Potassium permanga- nate, which is far less poisonous, is use- ful, especially from its deodorizing pow- er. While these substances can be em- ployed in the form of a spray, and thus diffused through an apartment, they should be replaced in many cases by gaseous agents, which can more readily pursue the disease germs floating in the air. Of gaseous disinfectants, choice is had between formaldehyde, sulfurous acid, chlorin and bromin, and to this list may be added also iodin. The results of recent researches prove that, of the agents available from their cheapnes disinfectants, corrosive sublimate, po- tassium permanganate, formaldehyde, 1068 THE STANDARD FORMULARY chlorin, bromin, and perhaps the zinc chlorid, are the only ones having suffi- cient germicidal power to be worthy of consideration. Disinfectants and Antiseptics — Prin- ciples to be Regarded in Use of. i. Seek to prevent the disease germs from rinding lodgment where they can multiply or long retain life. To this end, houses, and especially hospitals and pest- houses, must be thoroughly ventilated. Scatter these germs where there is plenty of light and air, and they become harm- less ; in damp, dark spots they retain their vitality a long time, but sunlight, thorough desiccation, and the oxidizing action of the air, will speedily destroy them. There must be no neglected places about cellars or basements where they can hide themselves and thrive and mul- tiply. Every part of the house, and, most of all, the drains, privy vaults, etc., whose function is to aid in dispos- ing of refuse material, must be kept scrupulously clean. In the instruction issued by the National Board of Health, these points are emphasized and reiter- ated : "Disinfection cannot compensate for want of cleanliness nor of ventila- tion." "The most available agents in combating infectious diseases are fresh air and cleanliness." 2. Endeavor to prevent the propaga- tion of these germs by sterilizing the soil on which they fall. Accumulations of refuse 'matter cannot be altogether avoided, but by the free use of antisep- tics they can be kept in such a condi- tion that spores will not readily germi- nate in them. It is well known that de- composing organic matter affords the most favorable possible soil for the growth of the lower forms of vegetable and animal organisms. While foul odors are not, in themselves, an evidence of the presence of contagion, they give warning that there is danger, and it is well to heed the warning. 3. Attack the germs themselves, and endeavor to lower or destroy their vital- ity. This is what is to be accomplished by the use of disinfectants; but the germs are organisms of a very low grade of life, and are therefore not easy to kill. The study of the various disinfectants, with especial reference to their relative value in different diseases or under different circumstances, there- fore becomes an important one. It is also essential to know the best means and modes of using them. Disinfectants, When and Where to Use. Disinfection of Excreta. — The infec- tious character of the dejecta of patients suffering from cholera and typhoid fev- er is well established, and this is true of mild cases and of the earliest stages of these diseases as well as of severe and fatal cases. It is probable that epidemic dysentery, summer complaint, diphtheria and other diseases are disseminated by means of the alvine discharges of the sick. These should therefore be thor- oughly disinfected. In cholera, diphthe- ria, yellow fever and scarlet fever, all vomited material should be regarded as infectious and should be disinfected. As in tuberculosis, diphtheria, scarlet fever and infectious pneumonia, the sputa should be disinfected or destroyed by fire. Disinfection of the Person. — The sur- face of the body of a sick person, or of his attendants, when soiled with infec- tious discharges, should be at once cleansed with a suitable disinfecting agent. For this purpose Labarraque's solution, diluted with five times its vol- ume of water, may be used. After care- fully washing soiled surfaces with this solution, the disinfectant itself is to be washed away with a towel wet with water or with diluted alcohol, 1 part to 10. The surface of the body of the dead may be disinfected by the use of the same solution, and cloths wet with this solution should be placed over ori- fices from which infectious material is likely to escape. In diseases like small-pox and scarlet DOMESTIC UTILITIES. 1069 fever, in which the infectious agent is given off from the entire surface of the body, occasional ablutions with Labarra- que's solution, diluted with 20 parts of water, will be more suitable than the stronger solution above recommended. Disinfection of Clothing. — Boiling for half an hour will destroy the vitality of all known disease germs, and there is no better way of disinfecting clothing and bedding which can be washed, than to put it through the ordinary opera- tions of the laundry. No delay should occur, however, between the time of re- moving soiled clothing from the person or bed of the sick and its immersion into boiling water. If circumstances make it impracticable to do this at once, clothing should be immersed in a suita- ble disinfecting fluid. For the complete disinfection of an apartment in which there has been a case of infectious disease, it is necessary to fill the room completely with formal- dehyde vapor, chlorin, bromin or sulfur- ous acid gas, and to keep it shut up for several hours, until every crevice is thoroughly penetrated and permeated by the disinfectant. But this thorough use of disinfectants is only admissible for the prevention of contagion after the re- covery or death of the patient. Disinfection of Privy Vaults, Cess- Pools, Etc. — When the excreta — not pre- viously disinfected— of patients with cholera or typhoid fever, have been thrown into a privy vault this should be infected, and disinfection should be re- sorted to as soon as the fact is discov- ered, or whenever there is reasonable suspicion that such is the case. This •may be accomplished with corrosive sub- limate or with chlorinated lime. The amount used must be in proportion to the amount of material to be disin- fected. Disinfection of Apartments. — In the sick-room no disinfectant can take the place of free ventilation and cleanliness. It is an axiom in sanitary science that it is impracticable to disinfect an occupied apartment; for the reason that disease germs are not destroyed by the presence in the atmosphere of any known disin- fectant in respirable quantity. Bad odors may be neutralized, but this does not constitute disinfection in the proper sense of the term. These bad odors are, for the most part, an indication of want of cleanliness or of proper ventilation ; and it is better to turn contaminated air out of doors than to attempt to purify it by the use of volatile chemical agents, such as carbolic acid, chlorin, etc., which are all more or less offensive to the sick and are useless as far as real disinfec- tion is concerned. Use i pound of corrosive sublimate for every 500 pounds — estimated — of fecal matter contained in the vault, or 1 pound of chlorinated lime to every 30 pounds. Disinfection of Ingesta. — It is well es- tablished that cholera and typhoid fever are very frequently and perhaps usually transmitted through the medium of in- fected water or articles of food, and especially milk. Fortunately there is a simple means at hand for disinfecting such infected fluids. This consists in the application of heat. The boiling temperature maintained for half an hour kills all known disease germs. So far as the germs of cholera, yellow fev- er and diphtheria are concerned, there is good reason to believe that a temper- ature considerably below the boiling point of water will destroy them. But in order to keep on the safe side it is best not to trust anything short of the boiling point, ioo° C. (212 F.) when the object in view is to disinfect food or drink which is open to suspicion of containing the germs of any infectious disease. During the prevalence of an epidemic of cholera, it is well to boil all water for drinking purposes, unless it comes from a source which is beyond suspicion, and especially if it is obtained from wells, or from rivers receiving the sewage of towns, etc. After boiling, the water may 1070 THE STANDARD FORMULARY be filtered, if necessary, and then cooled with ice placed around the water ves- sel, not put directly into the water. Forms of Disinfectants. — Disinfect- ants may be used in the form of gases, as in chlorin, bromin or sulfur fumiga- tion, or they may be used as liquids to be sprinkled about the sick room or poured upon cloths suspended about the room or poured upon excreta and other infected or infectious matter, or as li- quids to be sprayed about the room by means of an atomizer (so-called aro- matic disinfectants are used in this man- ner) ; they may be used as powders which consist of inert powder mixed with disinfectants; or the latter mix- ture may be formed into cakes; the dis- infectants may also be used as pastilles, to be ignited in the room. The fumi- gating pastilles, powders, etc., of Part IV are also used with the idea of pro- viding disinfection, but their disinfect- ing powers are very weak indeed. The incenses are also used for a similar pur- pose and are similarly inefficacious. Formaldehyde as a Disinfectant. Perhaps the most popular and most modern substance for room and house disinfection is formaldehyde, which is recognized by the U. S. P. under the name solution of formaldehyde and con- tains 40% of formic aldehyde. The lat- ter substance is formed by the incom- plete oxidation of methyl alcohol. Un- der certain conditions it forms a solid polymeric modification known as para- form. Formaldehyde may be applied direct- ly, in the form of a 57c solution, to sub- stances that require disinfection, and in the case of refuse, excreta and similar substances should be thoroughly mixed with them. A 5% solution of formalde- hyde is generally regarded as superior to carbolic acid of the same strength as a general disinfectant. In disinfecting with gaseous formal- dehyde it is important that the com- partments to be disinfected be tightly closed so that a sufficient concentration of gas may be held in contact with the infected substances a sufficient length of time. The temperature of the air is an important factor in securing efficient ac- tion, formaldehyde being much more energetic in a warm atmosphere than in a cold one. The best authorities state that gaseous formaldehyde disinfection should not be attempted if the tempera- ture of air is below io° C. The gas is most conveniently secured by liberating it from the 40% solution or from the solid paraform. A number of methods of accomplishing this, among which are the following ; Heating Under Pressure. — Portable autoclaves specially designed for the purpose are charged with a sufficient amount of formaldehyde, the quantity depending upon the cubic air space to be disinfected. The autoclave is closed and heat is applied until the required pres- sure within the autoclave is attained. The gas which has been liberated from the solution by the heat is allowed to flow through an outlet tube into the room or rooms which are to be disin- fected. The room is then closed for 2 to 12 hours, the shorter time if only smooth surfaces are to be acted upon, the longer if penetration into fabrics is desired. Ten ounces of formaldehyde should be used for each 1000 cubic feet of air space. Heating Without Pressure. — This method is similar to the preceding. The formaldehyde is placed in a specially de- signed retort and heated with a lamp. The gas is conducted into the compart- ment to be disinfected by means of a small tube which passes through the keyhole or other small aperture. The evolution of gas by this method takes place more slowly than when generated under pressure and a longer time is re- quired for disinfection. The rooms should remain closed for at least 6 hours, and for 12 hours if penetration into the interior of fabrics, etc., is de- sired. DOMESTIC UTILITIES. 1071 Spraying Method. — In this, the for- maldehyde is sprayed upon the objects which require disinfection or upon sheets which are hung up in the com- partment containing the infected mate- rials. The gas is liberated by simple evaporation, this evaporation being fa- vored by the wide surface which is ex- posed. Chemical Means. — Several methods of liberating formaldehyde from the solu- tion without the use of artificial heat have been proposed. The most impor- tant of these is known as the "perman- ganate method." The formaldehyde is poured on potassium permanganate when a violent chemical reaction takes place immediately, heat is generated, and a rapid liberation of formaldehyde gas takes place. Experiments have shown that when the formaldehyde and permanganate are mixed in the propor- tion of 6 of the former to 5 of the lat- ter, by weight, 50% of the formalde- hyde employed is liberated in the form of gas. Therefore twice as much for- maldehyde will be required for disin- fection as when any of the preceding methods are employed. Heating Paraform. — Lamps provided with a pan for holding the paraform are obtainable. Place the paraform on the pan and apply heat by means of an alcohol lamp. The evolution of gas in this manner is slow. Two ounces of paraform are required for the disinfec- tion of 1000 cubic feet of space. Burning of Wood Alcohol.— -There are various lamps made which incompletely burn or oxidize wood alcohol, formic aldehyde (formaldehyde) being the product of this oxidation. Method of the Health Department of Chicago.— The Health Department of Chicago disinfects rooms and entire dwellings simply by suspending therein sheets thoroughly sprayed with formal- dehyde. Sheets of ordinary size will hold from 5 to 6 ounces of liquid with- out dripping and this quantity has been found to be sufficient for the thorough disinfection of 1000 cubic feet of air space, the rooms being sealed and al- lowed to remain closed for 5 hours. More than one sheet may be used if necessary. When the room is opened, the density of the gas is still so great as to preclude respiration until after doors and windows have been opened for some little time. On the other hand, the air is respirable within a very few. minutes after the sheet has been re- moved, and there is no lingering smell of formaldehyde for days after, as is the case when the gas is evolved by the action of heat. This is due to the fact that some paraform is produced by the heat, this being retained in the meshes of the fabric, to be slowly converted into the gaseous form through several succeeding days. Disinfectant Liquids of the N. F. and U. S. P. The U. S. P. recognizes Solution of Zinc Chlorid and Solution of Chlorin- ated Soda, the N. F. mentions Com- pound Solution of Zinc and Aluminum and Compound Solution of Zinc and Iron. For formulas for these, see Part I. Other disinfectants are mentioned below. I. Aluminium chlorid . . Calcium chlorfd Sodium chlorid Zinc chlorid Water, to make Dissolve the aluminium and calcium salts separately, then mix and allow to settle. In the clear supernatant liquid dissolve the other ingredients. This mixture may be aromatized by the addition of oils of eucalyptus and wintergreen, or oil of rosemary and thymol may be added. II. Alum av.oz. 10 Sodium carbonate av.oz. 10 Ammonium chlorid av.oz. 2 Sodium chlorid av.oz. 2 Zinc chlorid • • • • av.oz. 1 Muriatic acid, commercial, Water, of each sufficient .av.oz. 6 .av.oz. 3 .av.oz. 2 .av.oz. lYz . .fl.oz. 32 10T2 THE STANDARD FORMULARY Dissolve the alum in y 2 gallon of boil- ing water, then add the soda which pre- cipitates the aluminium hydrate. Muri- atic acid should then be added in suffi- cient quantity to dissolve the precipi- tate. The other salts should then be dissolved in 3 pints of water ; this'should be added to the first solution, and then enough water added to make 1 gallon. III. Cresylic acid av.oz. 40 Rosin av.oz. 8 Caustic potash av.oz. 1, dr. 1 Water, to make gall. Y2 Place the cresylic acid in a suitable dish, add the rosin, and apply heat until the latter is melted and dissolved. Dis- solve the potassa in about 5 fluidounces of water, add to the previous mixture and boil until the rosin is completely saponified as shown by the liquid be- coming clear and homogeneous. Cool and add enough water to make Yi gal- lon. If the caustic potash is less than 85% in strength, more of it will be required. If saponification is not completed after 30 minutes boiling, it is an indication that more caustic potash is needed. The cresylic acid for this purpose is the crude article, which may be pur- chased cheaply. DOSES, RULES FOR. Wiggins' rules for doses are as fol- lows: 1. The dose of all infusions is 1 to 2 fluidounces, except digitalis, which is 2 to 4 fluidrams. 2. All poisonous tinctures, 5 to 20 minims, except tincture of aconite, which is 1 to 10 minims. 3. All wines, from Y2 to 1 fluidram, except wine of opium, which is 5 to 15 minims. 4. Most solid extracts can be given in doses of Yz to 1 grain; the exceptions are the extracts of poisonous drugs. 5. All diluted acids, from 5 to 20 minims, except hydrocyanic acid, which is from 2 to 5 minims. 6. All waters, from 1 to 2 fluid- ounces, except chloroform, creosote, cherry-laurel, bitter almond, and am- monia waters. 7. Medicated syrups, usually from Y2 to 2 fluidrams. 8. Mixtures, from 1 to 4 fluidrams. 9. Spirits, from ^ to 1 fluidram, ex- cept spirit of glonoin. 10. Essential oils, 1 to 5 drops. Young's rule to determine the dose of a child is to divide the age of the child by the age plus 12; the quotient repre- sents the portion of the adult dose to be given to the child. For example : The age of the child is 6; divide 6 by 6 plus 12 = 6/18=^3; a 6-year-old should re- ceive Yi of the dose given to an adult. DRAIN BOARDS, Copper, To Clean. Copper drain boards at bars and soda fountains may be cleaned quickly and satisfactorily with the following mix- ture : Whiting parts 4 Tripoli parts 3 Oxalic acid, powder part 1 DRIERS FOR PAINTS AND VAR- NISHES. (Siccatives.) Manganese borate alone may be used as a solid drier ; however, its action is usually too powerful, and it is generally mixed with other substances. The fol- lowing mixtures are used : Zinc oxid, 4 parts, manganese borate 1 part ; and equal parts zinc oxid and manganese borate. The manganese borate may be pre- pared from the residue remaining after the extraction of chlorin from a mix- ture of black oxid of manganese and hydrochloric acid. Cobalt borate may be employed in- stead of the manganese borate. Liquid drier may be produced by heating 100 parts of linseed oil over the naked flame, stirring constantly until it weighs 85 parts. DYES FOR EASTER EGGS. See Egg Dyes (liquid and dry). DOMESTIC UTILITIES. 1073 DYES, DOMESTIC. The formulas here given are the old- fashioned kind which housewives used before the various coal-tar dyes became so common. The different dyewoods were used, usually in conjunction with a mordant, also various chemicals such as copperas, blue vitriol, oxalic acid, alum, Prussian blue, ferrocyanid and bichrom- ate of potash, sugar of lead, etc. All goods should be well washed with soap and water before dyeing, rinsed thoroughly with clean water, and then immersed in the dyeing liquid. In mak- ing the latter, the chemicals and ex- tracts that are used should be thorough- ly dissolved, and the solutions should al- ways be strained to remove insoluble particles or mechanical impurities. The dyeing liquid is usually employed in a hot or boiling condition, and the goods dyed in it should be stirred about almost constantly to permit of an even distribution of the dye, that is, to pre- vent spotting. Fresh water, such as rain water, should be used whenever possible, as the salts in hard water decompose some of the chemicals used in dyeing. The volume of liquid used should al- ways be sufficient to completely cover the goods. If it does not do so, more water must be added and, if necessary, more of the dye. The quantities in the formulas here given are usually sufficient for from I to 2 pounds of goods. I. Black (for cotton and wool) : Extract of logwood av.oz. 2 Copper sulfate av.oz. 1 Dissolve each one separately in hot water. Saturate the goods in the cop- per solution, then pour this liquid into the logwood solution. Keep the mix- ture at almost the boiling point for 20 minutes ; if the goods is cotton, boil for 10 minutes. The goods should be stirred constantly to prevent spotting. To set the color, dissolve 8 ounces of common salt in a gallon of hot water, dip the goods in this solution, let remain until cold, and then hang them up to dry without wringing. Instead of the extract of logwood, 1 pound of the chips may be used. II. Blue (for cotton and wool) : Copperas av.oz. 1 Potassium ferrocyanid ...av.oz. Yz Sulfuric acid m. 160, Boil the goods in a solution of the copperas in water. In a brass or enam- eled kettle, dissolve the ferrocyanid in water, add the acid, then transfer the goods from the copperas solution to the ferrocyanid solution. If the color is not satisfactory, repeat this process sev- eral times. Or use the following: Prussian blue av.oz. 1 Oxalic acid av.oz. Yi Dissolve together in hot water, soak the goods in the solution until the de- sired shade is obtained, then wring out, and rinse in alum water. Or the following may be used : Red prussiate of potash av.oz. 2 Tartaric acid av.oz. Y* Oxalic acid av.oz. Y2 Mordant No. 2 (see below). fl.dr. 3 Dissolve the solids in water heated to near the boiling point, add the mordant, soak the goods in the liquid for 1^2 hours, then remove them, drain, rinse in clean water, and hang up to dry. III. Brown (for cotton and wool) : Catechu av.oz. 2 Copper sulfate av.oz. Ya Potassium bichromate av.oz. %. Dissolve the catechu in water, im- merse the goods in the liquid, and boil for 20 minutes, stirring constantly mean- while. Also dissolve the two salts in water, remove the goods from the cate- chu solution, allow them to drain fairly well, then transfer them to the second solution, and allow them to remain un- til they have the desired shade. . Finally rinse in clean water and hang up to dry. The following is a lighter color for wool only: Fustic av.oz. 5 Madder av.oz. 3 Camwood av.oz. 2 1 £ Cream of tartar av.oz. Y^ 1074 THE STANDARD FORMULARY Boil this mixture for 10 minutes with water, allow to cool, strain, add the goods, boil for about an hour, stirring frequently meanwhile, then add Vi av. ounce of copper sulfate dissolved in water, boil again for 20 minutes, then add 24 av. ounce of copperas to the so- lution to darken the color, rinse the goods in clean water, and hang up to dry. IV. Drab (for wool) : Camwood •• • .av.oz. 1 54 Sumach av.oz. V\ Fustic av.oz. 54 Logwood av.oz. }4 Cream of tartar av.oz. y 2 Boil this mixture with water for 10 minutes, strain, immerse the goods in the liquid, and boil for an hour, stirring frequently meanwhile. Then add 54 av. ounce of copperas, previously dis- solved in some water, to the dyeing liquid, and continue boiling for 20 min- utes. Then allow to cool, drain the goods, rinse in clean water, and hang up to dry. V. Green (for cotton and wool) : Color the goods blue as described above, then treat with the yellow dye. The combination of blue and yellow makes the green color. VI. Olive (for wool) : Two liquids are to be prepared. A. Potassium bichromate av.oz. y 2 Cream of tartar av.oz. J^ Alum av.oz. 1 )/+ B. Fustic av.oz. 3 Madder av.oz. 3 Logwood av.oz. 1 Dissolve the salts in A in water and boil the goods in this solution for an hour. Allow the liquid to cool, remove the goods, allow them to drain, and rinse in clean water. Then boil the sol- ids in B with water for 10 minutes, strain the liquid, soak the goods in this solution, agitate thoroughly, and boil slowly for one-half hour; then to the liquid add x / 2 av. ounce of copper sul- fate, stir the goods thoroughly again, remove from the liquid, allow them to drain, rinse in clean water, and hang up to dry. VII. Orange (for cotton and wool) : Color yellow according to the formula for yellow dye and before rinsing in fresh water, dip the goods in lime water. This one is for cotton only: Annatto av.oz. Vz Soda ash av.oz. 2 Macerate the two in enough warm water practically to dissolve them, strain the liquid, and add enough hot water to cover the goods. Then introduce the latter, allow to remain 15 minutes, stir- ring constantly meanwhile, then remove from the bath, allow them to drain, rinse in clean water, and hang up to dry. VIII. Pink (for wool) : Boil Yz av. ounce of powdered cochi- neal for half an hour with water, strain to remove all solid matter. Immerse the goods in alum water until thoroughly soaked, then transfer to the cochineal liquid, and allow to remain until the de- sired shade is obtained. IX. Purple (for wool and cotton) : Boil up 2 av. ounces of cudbear with some water. First immerse the goods in saleratus water (sodium bicarbon- ate) until well saturated, then wring out. and transfer to the cudbear liquid, allowing to remain for half an hour. If a darker shade is desired, again dip the goods in saleratus water, then transfer to cudbear liquid to which 2 av. ounces of alum has previously been added. X. Red (for wool) : Alum av.oz. 3 Cream of tartar av.oz. 1 Mordant Xo. 1 (see below) .fl.oz. 1 Dissolve in water, immerse the goods in the solution, boil for about 2 hours, then remove from the liquid, and drain for about 12 hours. Mix 12 ounces of madder with some water, boil for a short time, strain the liquid, immerse the goods, and bring the whole to boil- ing for about 12 hours. Finally remove DOMESTIC UTILITIES. m the goods, allow them to drain, rinse in fresh water, and hang up to dry. XL Scarlet (for wool) : Cochineal, powder av.oz. I Cream of tartar av.oz. }£ Mordant No. i (see below) .fl.oz. 2 An iron kettle should be used. Mix the cochineal with the water, bring to a boil, and add the cream of tartar and mordant. Then immerse the goods and boil for an hour, stirring the goods con- stantly meanwhile ; remove them from the bath, rinse in fresh water, and hang up to dry. XII. Slate (for wool) : Sumac av.oz. y 2 Cudbear av.oz. y 2 Logwood av.oz. $4 Cream of tartar av.oz. y 2 Boil these substances with water till well extracted, strain the liquid, to the latter add the goods, and boil slowly for an hour. Then to the bath add 24 ounce of copperas, first dissolved in some wa- ter, continue the heat for another 20 minutes, remove the goods, rinse them in fresh water, and finally hang them up to dry. XIII. Stone color (for wool) : Logwood Madder Sumac Fustic Cream of tartar Prepare like the preceding, using M av. ounce of copperas to darken the goods. XIV. Yellow (for cotton and wool) : Lead acetate av.oz. 2 Potassium bichromate av.oz. 1 Dissolve the salts separately in water; dip the goods first in the lead water un- til well saturated, then wring out, and dip in the bichromate solution ; then rinse in fresh water, and hang up to dry. Repeat the process if the color is not deep enough. The Mordants. No. 1. Cream of tartar av.oz. 2 Metallic tin av.oz. 2 Hydrochloric acid av.oz. 10 Sulfuric acid av.oz. 6 av.oz. Y\ av.oz. Yz av.oz. 1 av.oz. iyi av.oz. Y 2 Nitric acid av.oz. 24 Water fl.oz. 4 Mix the first three ingredients in a stone vessel, then add the sulfuric acid previously diluted with the water, and finally stir in the nitric acid, adding the latter slowly. No. 2. Metallic tin av.oz. l / 2 Hydrochloric acid av.oz. 10 Sulfuric acid av.oz. 10 Nitric acid . av.oz, 10 Water fl.oz. 10 Prepare like the preceding. DYEING OF LEATHER. I. Black: Treat with a solution of ferrous sul- fate or iron acetate. The leather may first be mordanted with a solution of extract of logwood. II. Blue: Extract 150 grains of nutgall with 32 fluidounces of water and brush the leather with this liquid. Then brush over with a solution of 150 grains solu- ble blue aniline and 75 grains of glue in 32 fluidounces of water. Use each mix- ture three times, then dry and finish with yelk of egg. III. Brown: Apply an intimate mixture of 4 av.oz. of umber (raw or burnt), x / 2 av.oz. of lampblack, and 17 fluidounces of oxgall. IV. Green : Dissolve 1 av. ounce of alum in 1 gal- lon of water which furnishes the mor- dant. The dye consists of 4 av. ounces of indigo-carmine dissolved in 7 pints of boiling water, 2 pints of strong decoc- tion of fustic, and 8 fluidounces of log- wood. V. Red: Apply a tincture made from 1 av. ounce of cochineal and 16 fluidounces of 80% alcohol. VI. Yellow: Extract 1 av. ounce of turmeric and l / 2 av. ounce of gamboge with 24 fluid- ounces. The leather requires mordant- 1076 THE STANDARD FORMULARY ing with a solution of alum or potas- sium carbonate before applying the dye. DYEING with Tube Paints. Another process for dyeing fabrics of all kinds, feathers, etc., is by means of tube paints. Any desired color may be obtained by using the corresponding paint. The latter must always be fresh and soft to obtain a satisfactory result. The immersing liquid is to consist of i ounce of chloroform, i ounce of am- monia water, and I gallon of gasoline, although the latter alone would probably work just as well. To dye the goods rub up the paint with some chloroform to a thin paste and add a sufficient quan- tity of the immersing liquid to dilute properly. Then pass the feathers, fab- ric, or other goods through the liquid, and wave them about in the air for a moment when they will be entirely dried. This is a ver} r expeditious proc- ess. If one dipping does not yield a satisfactor}' color, the article may be redipped. EGG COLORS (Liquid). Easter egg colors or dyes may be pre- pared in the liquid form by adding a so- lution of any suitable aniline or coal tar dye in wood alcohol to a solution of shellac in wood alcohol. If the odor of wood alcohol be objectionable, a highly purified methyl alcohol (there are vari- ous brands now obtainable) or ordinary alcohol may be used instead. The shel- lac may be replaced with mastic if its color interferes in any way with the beauty of the dyes. About 2 av. ounces of the resin should be dissolved in enough alcohol to make a pint of solution. Sufficient of the coal tar dye solution is to be added to im- part the proper tint, the amount re- quired depending upon the coloring power of the dye and upon the concen- tration of the solution. This liquid dye may be put up for sale in 2-dram square vials with a brush attached to the stopper, in a manner similar to liquid corn cure. In using, boil the eggs for 5 minutes in water, then remove them one by one, dry them well, and paint on the dye. EGGS OF PHARAOH'S SERPENTS. See Pharaoh's Serpents. ELECTRIC LIGHT GLOBES, to Color. Either of the following two formulas is entirely satisfactory: I. Dissolve any desired aniline dye (according to the color wanted) in alco- hol, making a strong solution, then mix this with about twice its volume of col- lodion. The dye used must be perfectly soluble in the alcohol and collodion as otherwise the coloring of the globes will be opaque. In using, immerse the globes in the liquid, then withdraw them, and turn them about so that the coating will be even. Then allow to dry, which takes place very quickly. If a heavier coating is desired, the globes must be dipped again in the liquid. II. Make a solution of the white of one egg in a pint of soft or distilled water, and filter, taking care that no bubbles remain on the surface of the liquid. The globes should be carefully cleaned and polished, and then dipped in this solution and hung up by a string to dry. After about half an hour, they should be dipped a second time to in- sure a perfect coating. When perfectly dry, dip in the coloring solution which" is to be made by dissolving 10 to 30 grains of any suitable coal-tar dye in 4 nuidounces of collodion, taking care that the dye is perfectly dissolved, as any undissolved particles will "spot" the globe. If the first coat does not make the globes dark enough, they may be dipped again after they have become dry. A straight-sided graduate or simi- lar vessel with straight sides is the best container for the coloring solution, as less liquid will be required than if some other container were used. DOMESTIC UTILITIES. 1077 III. White shellac av.oz. 3 Rosin, powder . av.oz. 1 Benzoin dr. 1 Alcohol fl.oz. 10 Dissolve the resins by frequent agita- tion, filter, and in the liquid dissolve any desired aniline color. The rosin may be omitted. The liquid is to be applied to the bulbs as in Nos. 1 and II. EMBALMING FLUIDS. These preparations contain such sub- stances as arsenic, formaldehyde, thy- mol, boric acid, saltpeter, glycerin and alcohol, arsenic having been in the past the favorite ingredient, it being now generally replaced by formaldehyde. I. The following is said to have been approved by the National Funeral Direc- tors' Association of the United States : Boric acid oz. 1 Borax oz. 2^ Potassium nitrate oz. 2^2 Glycerin oz. 4 Solution of formaldehyde oz. 11 Solution of eosin (1%) m. 30 Water, to make fl.oz. 80 Dissolve the acid, borax and niter in ,48 fluidounces of water, then add the glycerin, formaldehyde, eosin and bal- ance of the water. II. This formula is used by Mr. Wagner, secretary of the Missouri State Board of Embalmers : Mercuric chlorid dr. 3 Zine chlorid dr. 4 Arsenic av.oz. 1 ^2 Sodium chlorid av.oz. 2^4 Alum av.oz. 3 Solution of formalde- hyde fl.oz. 10 to 20 Water, to make fl.oz. 80 Dissolve the solids in a portion of the water, then add the formaldehyde and the remainder of the water. III. Dr. Hewson of Philadelphia, recommends the following: Sodium arsenate av.oz. 16 Glycerin fl.oz. 16 Formaldehyde fl.dr. 6 to 9 Water fl.oz. 64* Dissolve the arsenate in the water by the aid of heat, allow to cool, and add the other ingredients. This solution is said to perfectly pre- serve subjects (or specimens immersed in the solution), the body or specimens retaining the appearance presented by the healthy parts immediately after death. IV. Wickersheimer's Preserving Fluid. This is said to be the formula in Berlin : For For Injecting Immersing Arsenous acid gr. 30 gr. 22 Potassium carbonate.gr. 28 gr. 20 Potassium nitrate gr. 50 gr. 36 Potassium sulfate gr. 375 gr. 280 Sodium chlorid gr. 150 gr. 120 Wood alcohol fl.oz. 3 fl.oz. 3 Glycerin fl.oz. 16 fl.oz. 16 Water fl.oz. 80 fl.oz. 80 Dissolve the arsenic and potassium carbonate in some of the water by the aid of heat, dissolve the other salts in the remainder of the water, mix the two solutions, and add the other ingredi- ents. V. The following non-poisonous substitute was recommended by Hager in place of the preceding: Salicylic acid dr. 4 Boric acid dr. 5 Potassium carbonate dr. 1 Oil of cinnamon dr. 3 Oil of clove dr. 3 Glycerin fl.oz. 5 Alcohol fl.oz. 12 Water fl.oz. 12 Dissolve the first three ingredients in. water and glycerin by the aid of heat, dissolve the oils in the alcohol, and mix the two solutions. VI Dr. Tilton of the U. S. Army ad- vises the following: Solution of zinc chlorid, U. S. P ....gall, t Solution of sodium chlorid (6 oz. to t pint) pints 6 Solution of mercuric chlorid (1 oz. to 1 pint).. pints 4 Alcohol pints 4 Carbolic acid, pure... fl.oz. 8 Glycerin fl.oz. 24 Mix glycerin and carbolic acid, then all the other ingredients, when a clear solution of three gallons results, which icns THE STANDARD FORMULARY is the proper amount for a body weigh- ing 150 pounds. This may be injected into the aorta, but it is much less trouble to inject into the brachial or femoral artery, or the femoral vein. An anatomical syringe is desirable, but a gravity apparatus that will answer all purposes may be improvised with rubber tubing, stop- cock, etc. A fluidram is sufficient to preserve each ounce of animal weight. For human bodies it is well to calculate 2Y 2 flnidounces per pound weight. ENAMELED LETTERS, To Fasten to Glass. A thick mixture of white lead with varnish, will make a good cement for this purpose. ETCHING COPPER, Liquid for. Solution of ferric chlorid, U. S. P fl.oz. 13 Sodium chlorid av.oz. 4^4 Mix and dissolve. — H. ETCHING OP GLASS, TIN AND ZINC. See Ink, Diamond, Ink for Writing on Metals, and Ink for Zinc Labels. Also the next subject. ETCHING OF GLASSWARE. Very often the druggist would like to etch glassware such as reagent bot- tles and their stoppers, receiving bottles for percolates and filtrates, etc. The only available method for doing this on the small scale is by means of hydro- fluoric acid gas generated for this pur- pose from calcium fluorid and concen- trated sulfuric acid. The glass to be etched is first cleaned with soap and water to remove all traces of grease, then dried, after which it is to be covered with a thin coating of melted wax or paraffin which may be applied by means of a suitable brush or swab, or the article, if small, may be dipped directly into the melted wax or paraffin. The design to be etched on the glass may be traced by means of a needle, knife point or other simi- lar means which will suggest itself. The excess of wax is to be brushed off and all the lines' of the design should be clear. As stated a mixture of cal- cium fluorid and concentrated sulfuric acid is used for etching. A lead dish is the only kind suitable for mixing these two substances. This may be made from any available piece of lead like a short section of lead pipe cut open down the side and then hammered out. Fill the dish about one-third full with powdered calcium fluorid, then add enough of the sulfuric acid to make a thin paste, stirring with a stick of wood. The object to be etched is laid over the dish with the engraved side down in such a manner that the two fit quite snugly. Allow the whole to remain for from 2 to 4 hours, after which the wax is to be removed by scraping and washing with gasoline. If it is desired to make the design more visible, a lit- tle black varnish may be rubbed into the etched parts. Hydrofluoric acid gas is a very dele- terious substance to inhale and is dan- gerous even when it comes in contact with the skin. Great care should be ex- ercised during this etching process and the operation should be done under a hood or out of doors. See also "diamond ink" under heading Inks, Miscellaneous. ETCHING IRON AND STEEL Liquid for. I. Corrosive sublimate av.oz. l / 2 Tartaric acid gr. 20 Xitric acid m. 15 Water fl.oz. 12 Mix and dissolve. — H. TI. ...fl.oz. sy 2 . .av.oz. 1 . . .fl.oz. 5 Tincture of iodin Potassium iodid Distilled water Mix and dissolve. — H. III. This is an excellent formula for etching steel, marking cutlery, and the like : Copper sulfate gr. 15 Sodium chlorid gr. 10 Water fl.oz. 10 Mix and let stand for 1 or 2 hours. DOMESTIC UTILITIES. 1079 In using cover the steel first with soap or melted wax, trace the design with some sharp instrument, then apply the solution with a brush, allowing it to etch into the metal. After a few minutes the object can be dipped into hot water and the wax or soap be re- moved. FEATHERS, BLEACHING OF. Feathers turned yellow are bleached according to one process by soaking them for a few hours in a warm soap bath (78 to 85 ° C.) which should not be too strong, rinsing and exposing them, strung upon a thread, for some time to the sun, frequently moistening them meanwhile. According to another process, the feathers, after having been treated in the warm soap bath, should be rinsed off and transferred to water acidulated with sulfurous acid. Here they should be allowed to remain for 20 or 30 hours, then washed, drawn through a weak, lukewarm soap bath, and dried in the sun, or left in the sun for I or 2 days, being frequently moistened. According to Dobereiner, a solution of ammonium carbonate is the best means of bleaching feathers as it effects the purpose much quicker than sulfur- ous acid. FERTILIZERS. These are intended for the fertiliza- tion of garden and flowering plants. They are put un in powder form and sold under such names as "Plant and Flower Food," "Lawn Fertilizers," "Chemical Food for Plant," "Plant In- visrorator " etc. Ammonium sulfate av.oz. 8 Potassium nitrate av.oz. 4 Sugar av.oz. 2 Each ingredient in moderately fine powder is mixed by passing through a sieve. It could be put up in packages to sell for 25 cents per pound. The di- rections for use are : One teaspoonful in a gallon of water, to be used in sprinkling upon the plant after sun- down about twice a week. II. Calcium phosphate av.oz. 4 Potassium nitrate av.oz. 1 Potassium phosphate av.oz. 1 Magnesium sulfate av.oz. 1 Iron (ferric) phos- phate gr. 90 to 175 Mix well. In using, mix 30 grains with 1 quart of water and with this sprinkle the plants. A superior mixture is produced by using instead of the insoluble calcium phosphate, the soluble acid "superphos- phate." III. Sodium phosphate av.oz. 4 Sodium nitrate av.oz. 3 Ammonium chlorid av.oz. 2 If this is to be dispensed in liquid form, this mixture should be dissolved in 5 pints of water. When use.d the solution should be diluted with 100 times the proportion of water. IV. This was recommended by the Horticultural Review for fertilizing lawns : Potassium nitrate av.oz. 2 Sodium nitrate av.oz. 2 Calcium sulfate av.oz. 2 Calcium superphosphate. .. .av.oz. 2 One ounce of this mixture is suffi- cient for 10 gallons of water. FILTER PAPER TOUGHENED. Filter paper may be toughened by immersing in concentrated nitric acid and washing with water. It is then re- markably toughened, the product being pervious to liquids, and quite different to the parchment paper made by means of sulfuric acid. It can be washed like a piece of linen. So treated it con- tracts in size, and the ash is dimin- ished, the weight is slightly reduced, and it contains no nitrogen. The tough- ened paper can be used with the vac- uum-pump in ordinary funnels, without extra support, and fits sufficiently close to prevent undue access of air, which is not the case with parchment paper. 1080 THE STANDARD FORMULARY Another admirable way of preparing fil- ters is this : Dip only the apex of the folded paper into nitric acid, and then wash with water; the weak part is thus effectually toughened. FIRES, COLORED. The so-called "colored fires" are com- posed essentially of three kinds of in- gredients, viz,. : a combustible, an oxy- gen producer, and a coloring agent. The cheaper "fires" usually contain sulfur as a combustible, while the better ones contain shellac, sometimes lycopodium. Those containing sulfur are not adapted to indoor use because of the irrespir- able sulfurous acid gas which is pro- duced. It is to be noted, also, that "fires" containing a poison like an ar- senic compound or calomel are also not to be employed for in-door use. The second kind of ingredient, the oxygen producer, is usually potassium chlorate or potassium nitrate. The coloring agents depends, of course, upon the color desired — a bar- ium salt being used for red, a strontium salt for green, a copper salt for blue, etc. The ingredients of "fires" should al- ways be quite dry; in fact, it may be necessary to dry them before mixing. They should also be in moderately fine powder. Shellac, which, as is stated, is a common ingredient of these "fires," may be reduced to requisite fineness by grinding in a drug mill. The ingredi- ents now dried and powdered may be mixed by means of the hand or a wood- en (not steel) spatula. Triturating or rubbing in any way like to cause much friction, must be avoided because of the danger of spontaneous combustion. Fireworks manufacturers are said to make these "fires" by melting the shel- lac, stirring in the color-bearing com- pound (barium or strontium nitrate, etc.), allowing the mixture to cool, and granulating. Then potassium chlorate and other ingredients are then added. To increase the brilliancy, metallic mag- nesium is sometimes added in the pro- portion of about one dram to the pound. So-called "tableau lights" are colored fires, and being then intended almost entirely for indoor use, there should be no sulfur, arsenic, mercury, or other deleterious substances present, as stated above. A "quick light" for "touching off" tableau lights may be made by mixing 30 grains each of potassium chlorate and sugar. This is about or sufficient quantity for one light. Place it along- side of the tableau light and set fire to it. The rapidity .of combustion of these "fires" or "lights" depends upon the proportion of the various ingredients. If, for example, there is a large pro- portion of the combustible ingredient, shellac or sulfur, the mixture burns more rapidly than when a smaller pro- portion is present. The formulas given on these pages may therefore be varied somewhat by increasing or decreasing the- combustible, according as a rapid or slow "fire" is wanted. Blue Fire. These "fires" are of different shades of blue. I. Sulfur av.oz. 2 Potassium sulfate av.oz. 2 Ammonio-sulfate of copper. av.oz. 2 Potassium nitrate av.oz. 3^2 Potassium chlorate av.oz. 3^ II. Potassium nitrate av.oz. 8 Antimony sulfid. black av.oz. 4 Zinc (metallic) av.oz. 2 III. Potassium chlorate av.oz. 6 Alum, dried av.oz. 3 Shellac av.oz. 2 Sulfur av.oz. 1 IV. Potassium chlorate av.oz. 6 Calcium carbonate av.oz. 2 Malachite, powder av.oz. 1^ Sulfur av.oz. iV* DOMESTIC UTILITIES. 1081 8 2 2 this i 4 7 Brilliant Stars. Potassium nitrate av.oz Sulfur av.oz Black antimony av.oz Make this into a stiff paste with solution : Isinglass fl.oz Diluted acetic acid fl.oz Alcohol fl.oz. Form into small pieces, and while still moist roll in meal gunpowder. Crimson Fire. I. Strontium nitrate av.oz. n Sulfur : av.oz. 4 Charcoal, willow av.oz. 1 Potassium chlorate av.oz. 1 Strontium nitrate av.oz. 7 Potassium chlorate av.oz. 2 Shellac av.oz. 4 Charcoal av.oz. 1 II. Golden Bain. Potassium nitrate Gunpowder , Sulfur Charcoal Lampblack .av.oz. 8 .av.oz. 8 .av.oz. 5 .av.oz. 2 .av.oz. 1 Mix and fill into paper tubes. II Potassium nitrate. Sulfur Gunpowder Charcoal Lampblack . .av.oz. 8 . .av.oz. 4 . .av.oz. a . .av.oz. 1 ..av.oz. 1 L Green Fire. 4 14 5 for Potassium chlorate av.oz. Barium nitrate av.oz. Sulfur av.oz. Boric acid may be substituted the barium nitrate. II. Barium nitrate av.oz. 12 Potassium chlorate , . av.oz. 4 Shellac av.oz. 4* Boric acid may be substituted for the barium nitrate. III. Barium nitrate. . . . Potassium chlorate. Shellac Lycopodium ...... . .av.oz. 12 ..av.oz. 4 ..av.oz. 4 dr. 3 Boric acid mav be substituted for the barium nitrate. Lilac Fire. Potassium chlorate av.oz. 6 Shellac av.oz. 3 Chalk .._ av.oz. 3 Black oxid of copper av.oz. 1 Orange Red Fire. Chalk Sulfur Potassium chlorate... .av.oz. 5 .av.oz. 3 .av.oz. 12 Purple Fire. Black antimony . . . Copper oxid Sulfur Potassium nitrate. Potassium chlorate Red Fire av.oz. 1 av.oz. 3 av.oz. 6 av.oz. 6 av.oz. 12. See also Crimson, Orange Red, and Rose Fires. I. Strontium nitrate av.oz. 12 Shellac av.oz. 3 II. Strontium oxalate Lycopodium Milk sugar Potassium nitrate. Potassium chlorate III. Strontium nitrate.. Sugar Potassium chlorate. av.oz. 1 .av.oz. 1 .av.oz. 4 .av.oz. 4 .av.oz. 13 . .av.oz. 8 . .av.oz. 4 .av.oz. 1 IV. Potassium chlorate av.oz. 4 Shellac av.oz. 4 Strontium nitrate av.oz. 12 V. Strontium nitrate av.oz. 12 Potassium chlorate av.oz. 4 Shellac av.oz. 4 Lycopodium dr. 3 Rose Fire. Potassium nitrate av.oz. 8 Corn meal av.oz. 2 Charcoal av.oz. ] 2 Violet Fire. See also Lilac and Purple Fire^. Calcium carbonate av.oz. 2 Malachite av.oz. 2 Sulfur av.o Potassium chlorate av.oz. 6 1082 THE STANDARD FORMULARY White Fire. Stearic acid Barium carbonate.. Milk sugar Potassium nitrate.. Potassium chlorate. II. Stearic acid Sulfur Black antimony... Potassium nitrate. Yellow Fire. Sodium nitrate. . . . Potassium chlorate. Shellac av.oz. i .av.oz. i .av.oz. 4 .av.oz. 4 .av.oz. 13 .av.oz. 1 .av.oz. 1 .av.oz. 3 .av.oz. 6 av.oz. 12 .av.oz. 4 .av.oz. 4 II. Sodium oxalate Shellac Potassium nitrate Pcrtassium chlorate.... .av.oz. .av.oz. .av.oz. .av.oz. FIREWORKS PAPERS. These are sheets of bibulous paper saturated with appropriate solutions which, when ignited, burn for a longer or shorter time, as the case may be, with a brilliant colored flame resembling ''Bengal lights" (see Fires, Colored). The formulas here given emanate from a French authority. The directions for making these pa- pers are to steep unsized papers in the solutions, suspend the papers on a string stretched across a warm room, and allow to dry. Then roll tightly into rolls of suitable length, according to the length of time they are to burn. By rolling tightly a sheet of paper 12 by 16 inches may be made to burn for several minutes. In making these papers, every pre- caution against fire should be taken. In making the solutions, water-bath heat should be used. Fuses. An igniting paper, for "touching off" fireworks, may be made as follows : Potassium nitrate dr. i l / 2 Lead acetate av.oz. 4 Water fl.oz. 10 Mix and dissolve the solids. In this solution place sheets of blotting or other unsized paper, heat the liquid nearly to boiling, and keep at this tem- perature for 20 minutes. If the paper is to be "slow," it may be removed from the liquid, hung on strings to dry, cut into strips, and then rolled. If a quick-burning paper is wanted, the heating should be repeated with a fresh charge of the solution. FIRE-EXTINGUISHING HAND GRENADES. The following are supposed to rep- resent the results of analyses of these preparations : Hardens Extinguishing Grenade. — The solution contains 18.46% of sodium chlorid and 8.88% of ammonium chlorid. Hayward's Extinguishing Grenade. — The solution contains it.7% of cal- cium chlorid, and 5.6% of magnesium chlorid. Hayward's Hand Grenade. — The so- lution contains calcium chlorid, i8.47c ; magnesium chlorid, 5.7% ; sodium chlor- id, 1.3%; potassium bromid (?), 2.2%; barium chlorid, 0.3%. Martin's Fire Protector. — Glycerin, 2^2 ounces ; ammonium carbonate, 4 drams ; ammonium chlorid, 10 drams ; boric acid, 10 drams ; potassium bitar- trate, 1 dram; and potassium oxalate (?), 1 dram. Munich Fire Annihilating Powder consists of sodium chlorid, 43% ; alum, 19.5% ; sodium sulfate, 5% ; sodium car- bonate, 3.5% ; silica, 6.6% ; water, 22.37c. Schoenberg's Fire Annihilator. — The solution contains 1.66% of sodium car- bonate, and 6.43% of sodium chlorid. FIRE EXTINGUISHERS, Dry. I. Potassium nitrate, powder. av.oz. 15 Sulfur, powder av.oz. 9 Charcoal, wood, powder. . .av.oz. 1 Colcothar or rouge av.oz. j4 Dry them thoroughly, then mix them, and fill into round pasteboard boxes holding 5 pounds. Through an orifice in the side a fuse is introduced, which DOMESTIC UTILITIES. 1083 extends some 4 inches inward and about 6 inches outward. The latter end is fastened on the outside of the box, and a strip of red paper pasted upon it, bearing the inscription "light here." These extinguishers are intended for use in closed rooms, and automatically. This acts by absorbing oxygen. II. Sodium chlorid av.oz. 3 Ammonium chlorid av.oz. 3 Sodium bicarbonate av.oz. 4 III. Ammonium chlorid av.oz. 5 Sodium sulfate av.oz. 3 Sodium bicarbonate av.oz. 2 FIRE EXTINGUISHERS, Liquid. These solutions coat or encrust the burning substance with incombustible saline substances so as to prevent or at least hinder further burning. I. Calcium chlorid, crude. .. .av.oz. 4 Sodium chlorid av.oz. 1 Water fl.oz. 15 The resulting solution is thrown into the fire by a hand-pump. The burning portions become incrusted and cease to be combustible. II. Calcium chlorid .av.oz. 20 Salt av.oz. 5 Water fl.oz. 75 III. Sodium nitrate av.oz. 1 Sodium chlorid av.oz. 1 Ammonium chlorid av.oz. 1 Magnesium chlorid av.oz. 1 Water fl.oz. 16 IV. A fire-extinguishing preparation patented in 1881 was directed to be made from borax, sodium bicarbonate, aluminum sulfate, and sodium bisulfate. V. Lauber's Fire Extinguisher is said to consist of a 6% aqueous solution of a mixture of sodium chlorid, 50 parts so- dium bicarbonate 30 parts and alum 20 parts. VI. The Babcock fire extinguisher is charged with a solution of sodium bi- carbonate in water and sulfuric acid contained in a lead bottle which, when required, is turned over by a crank, - spilling the acid into the soda solution. The carbonic acid gas generated creates a pressure sufficient to force the water through the nozzle. About 5 parts of acid to 6 parts of soda, by weight, are considered the proper proportions. Other combinations are used such as ammon- ium carbonate, potash, etc. FIREPROOFING FABRICS, WOOD, PAPER, ETC. While fireproofing materials are used and formulas are here given, it should not be understood that the articles "fire- proofed" really cannot burn ; the prep- eration will simply hinder the rapid progress of the fire so as to permit of easy and rapid extinction. Among the substances used for fire- proofing are the following : Solution of sodium silicate, sodium tungstate, so- dium hyposulfite, boric acid, zinc chlor- id, calcium acetate, iron sulfate, copper sulfate, and common salt, but ammon- ium phosphate, or compounds contain- ing it, are said to be the best of all, and sodium tungstate ranks next in efficiency. I. Several years ago the Commis- sioner of Buildings of Chicago recom- mended or approved the following fire- proofing preparation as an application to wood, fabrics, etc., in theaters and other places : Dissolve in a suitable vessel one and one-half pounds of acid ammonium phosphate (diammonium phosphate) in a gallon of hot water. In another ves- sel mix three ounces of starch with 30 grains salicylic acid. Then add to this powder mixture enough hot water to make a thick paste, stirring the mass. Then add the ammonium phosphate solu- tion, gradually, to the starch paste, so as to obtain a homogeneous liquid. Of this solution not less, or not much less, is to be applied than the material (cloth or wood) is capable of absorbing. 1084 THE STANDARD FORMULARY FIXING BATH for Photography. Very often a solution of sodium hypo- sulfate in water is used, also the fol- lowing: I. Stanley Acid Fixing Bath: Sodium hyposulfite av.oz. 8 Alum av.oz. ^ Distilled water fl.oz. 32 Dissolve and filter. II. Sodium hyposulfite dr. 8 Sodium sulfite, dried dr. 4 Chrome alum dr. a Sulfuric acid m. 30 Distilled water, to make... fl.oz. 32 Dissolve the hyposulfite in half the water, dilute the acid with some water, dissolve the sulfite in some of the water, and the chrome alum in the remainder of the water. Add the diluted acid to the sulfite solution, then the hyposulfite solution, and finally the alum solution. If this solution is milky or becomes so, it is unfit for use. This is to be used for plates or paper without dilution. III. See also Toning Solutions. FLASH-LIGHT POWDERS. These powders are employed by pho- tographers for taking negatives in im- perfectly lighted places, or in the absence of good daylight. When blown into an alcohol flame these powders flare up suddenly, producing an intense actinic light. Finely pulverized magnesium (metal) alone may be used for this pur- pose; some claiming for this the best results, but it is also combined with gun cotton in the proportion of 2 parts to 1 of the latter. Other combinations of magnesium are also used. Of late, aluminum metal is displacing magne- sium, it being more economical and comparatively smokeless, while magne- sium produces a dense and persistent smoke. It must be remembered that these powders are very explosive and must- be prepared only in small quantities, as wanted. They should be mixed, not by trituration, but on a sheet of pap means of a horn or wooden spatula or a card. If desired, these powders may be dis- pensed in small capsules or envelopes of paper saturated with sodium or potas- sium nitrate. In this case it is only necessary to apply a match to the en- velope to set off the charge of powder. I. Magnesium (powder) ..av.oz. 3 Potassium permanganate. . .av.oz. 2 II. Magnesium (powder) av.oz. 4 Potassium permanganate. . .av.oz. 4 Barium peroxid av.oz. 2 III. Magnesium (powder) av.oz. 3 Antimony sulfid, black. .. .av.oz. 1 Potassium chlorate av.oz. 6 IV. Magnesium metal av.oz. 4 Potassium bichromate av.oz. 3 Potassium permanganate. . .av.oz. 3 Pulverize separately and mix care- fully. V. Magnesium metal av.oz. 4 Aluminum metal av.oz. 2 Potassium chlorate av.oz. 3 Potassium permanganate dr. 4^ FLEA EXTERMINATORS. There are two kinds of fleas, the hu- man flea and the dog and cat flea and either one may infest a house. Practic- ally all cats and dogs are inhabited by fleas and thus easilv become a source of infestation. The eggs of the dog and cat flea are deposited among the hairs of the animals but inasmuch as they are not attached to the hairs, numbers of them drop off whenever the animal moves and wherever he lies down. A rug or piece of carpet should there- fore be provided for the animal to lie upon and this should be shaken out frequently and the dust and dirt thus obtained should be gathered up and burned; or the rug may be treated with hot water which will effectually destroy all eggs. To Expel from a House. 1 I. To destroy fleas in a house or to DOMESTIC UTILITIES. 1085 expel them it has been recommended to throw or spray benzine or gasoline in the corners and all the crevices. A safer method is to sprinkle the floor thickly with quicklime, or better yet use good insect powder freely. Cleaner methods are to lay sprigs of. pennyroyal herb around the rooms, also to sprinkle or spray with an atomizer the follow- ing combination: Oil of pennyroyal fl.oz. 2 Oil of sassafras fl.oz. 2 Alcohol fl.oz. 4 II. Carbolic acid gr. 100 Oil of bergamot m. 50 Cologne water fl.oz. 4 Diluted alcohol fl.oz. 4 This is to be sprayed about the room, on clothing bedding, etc.— H. III. Oil of bergamot m. 50 Oil of thyme m. 50 Benzol fl.oz. 1 Alcohol fl.oz. 3 Use like the preceding. — H. To Remove from Animals. The U. S. Department of Agriculture recommends the free application of good insect powder, then wrapping the dog or cat in a towel for about half an hour, when the- fleas will be found dead in great numbers. IV. The New Hampshire Experi- ment Station has found creolin to be the most satisfactory remedy for the pest. For dogs a 3%. solution is recom- mended, and for cats a 2% solution. The animal should be thoroughly wash- ed, and the application will destroy the adult fleas as well as the larvae. The application should be made as soon as any infestation of dogs and cats is ob- served. It may be applied to dogs and cats by washing with the hand or brush or by submerging animals in the pre- pared solution. FLOOR OILS. So-called "floor oils" are various oily mixtures, such as the following: I. Neatsfoot, cottonseed and yellow paraffin oils, each equal parts. II. Paraffin oil, 8 parts, kerosene and lime water, each equal parts. III. Fish oil, 8 parts, paraffin oil and lime water, each 1 part. These are to be brushed on the floor or they may be applied occasionally by means of a mop. They are supposed to prevent the -dust from rising. While these mixtures when applied to floors naturally prevent, to an extent, dust from rising, they have some ob- jectionable qualities. Nos. II and III for example have the odor of kerosene and fish oil. The greasiness or non- drying property is also objectionable as this may do damage to rugs, carpets, clothing, etc. The customary way of oiling floors is apply boiled linseed, pref- erably mixed with some of the turpen- tine or japan dryer. This dries to a tough, resinous coating without any greasiness. Another method of oiling floors is with a solution of wax in oil of turpentine. FLOOR WAX in Powder. (Ballroom or Dance-Hall Powder.) Floor waxes may be in both liquid and powder forms. The latter are coarse, such as will pass through a No. 10 or 20 sieve, and are used by sprink- ling on the floor. The ingredients of these waxes are various waxy matters, sometimes in combination with talcum or boric acid. I. Paraffin wax av.lb. 1 Boric acid, powder av.lb. 7 Oil of lavender flowers. . .fl.dr. 1 Oil of neroli m. 20 Melt the paraffin, add the boric acid and the oils, mix well, and pass the mixture through a coarse sieve. The oils may be omitted as they are not necessary. II. Spermaceti av.oz. 4 Paraffin wax av.oz. 4 Talcum, powder av.oz. 8 Shave the spermaceti and paraffin quite fine, mix with the talcum, and pass through a No. 10 sieve. 1086 THE STANDARD FORMULARY III. Stearin, powder av.oz. 20 Yellow wax, powder av.oz. 5 Soap, powder av.oz. 2 IV. Stearin, powder av.oz. 16 Yellow wax, powder av.oz. 4 FLOOR WAX OR POLISH, Liquid. Instead of sprinkling floor wax in the powder form on dancing floors, which is a crude but simple way of treating floors prior to dancing, floor wax or pol- ish in liquid form should be preferred as this makes a more satisfactory re- sult. The base of these polishes is usu- ally beeswax which is either emulsion- ized with an alkaline solution or is dis- solved in oil of turpentine. The floor to be treated should be thoroughly cleaned and thoroughly dry. If not perfectly smooth, it should be made so by sandpapering or scraping followed by sandpapering. If there is any old paint, varnish or polish on the floor it should be removed with lye, then thoroughly washing and drying the floor. In using the polish it should be ap- plied in a thin coat, allowed to dry thor- oughly, then rubbed hard with brushes or cloths until a suitable gloss is ob- tained. The following preparations have been highly recommended as floor polishes : I. Dieterich's formula : Yellow wax av.oz. 8 Potassium carbonate av.oz. 1 Oil of turpentine fl.oz. 1 Water fl.oz. 32 Heat the wax and water to boiling ; add the potassium carbonate; boil an- other minute or until the wax is emul- sified; remove the vessel from the fire; add the oil, and stir until cold. If the floor is well preserved, 16 fluid- ounces more of water may be added. A brown color may be produced by add- ing sienna or umber, and a very dark brown, by the further addition of lamp- black. II. Hager's formula : Yellow wax av.oz. 8 Potassium carbonate av.oz. 4 Water fl.oz. 52 Heat the wax in an iron vessel with 40 fluidounces of water until the wax is melted, then add the ootassium car- bonate dissolved in the remainder of the water and boil together until solution is effected. If it be desired to color the polish, add ^2 to 1 av. ounce of annatto pre- viously dissolved in a little alcohol. III. Hager's formula: Yellow wax av.oz. 5 Paraffin wax av.oz. 2 Stearic acid av.oz. ic Oil of turpentine fl.oz. 6 Benzin fl.oz. 7 Melt together by a gentle heat (waxes and acid), add a sufficient quantity of burnt sienna thoroughly triturated with linseed oil varnish. Then add with a constant stirring (remote from fire), the oil and benzin. IV. Yellow wax av.oz. 5 Soap av.oz. 1 Potassium carbonate av.oz. 34 Water fl.oz. 68 First dissolve the soap in 10 fluid- ounces of water, heating gently, then add the wax, and boil. When the wax begins to come to the surface, add the potassium carbonate dissolved in 10 fluidounces of water; heat for 20 min- utes more, and then add the remainder of the water. Yellow wax av.oz. 10 Ceresin av.oz. 10 Burnt sienna av.oz. 2 Oil of tuTpentine ■ fl.oz. 12 Melt the w T ax and ceresin at a gentle heat, add the sienna previously tritur- ated to a smooth paste with a small amount of boiled linseed oil, mix well, allow to cool somewhat and then in- corporate the oil of turpentine or as much of it as is required to make a mass of the consistence of an ointment. DOMESTIC UTILITIES. 108? The burnt sienna may be used in larger or smaller quantity, according to the tint desired, or it may be re- placed by raw sienna, etc. VI. A simpler preparation than any of the preceding is a solution of i part of yellow wax in 2 parts of oil of turpentine, prepared by melting the wax on a water bath and then incorporating the oil. This polish will be as satisfactory as others if applied in a thin coat and the floor be rubbed thoroughly hard, when dry, until a good polish is ob- tained. FLOWER FOOD. See Fertilizers. FLOWERS, Coloring of. See Coloring Flowers. FLY EXTERMINATORS. There are several species of flies, the most common being the ordinary house fly. There is also a large blue Bottle fly and a small fly, also a horse or stable fly which latter is the only kind that bites. The U. S. Department of Agriculture determined, by means of a series of experiments that flies are prop- agated in horse manure and that the fly pest might be overcome by treating the manure with chlorid of lime or kerosene or by keeping it in closed screened boxes. Fly exterminators are of different kinds, such as papers, powders, pastilles, etc. The papers which are now so large- ly employed are of several varieties, viz. : sticky, poisonous or arsenical, and non-poisonous. Full directions are given below for making these preparations. Fly Lime. What is known as "fly lime," which is sold largely in Europe, consists of the mixtures used in the formulas for sticky fly paper. These mixtures are spread upon plates or saucers, which are then set about the room, or are painted upon sticks, which are then hung around in convenient places. Fly Paper (Arsenical or Poison). I. Potassium arsenate, crystal. av.oz. 1 Sugar av.oz. 4 Water ....fl.oz. 48 Dissolve and saturate heavy unsized paper in the solution; afterward hang it- up to dry on strings. The paper should be stamped or printed as pois- onous previous to immersion in the liquid. Potassium arsenate should be employed, or this prepared from arsen- ic acid, instead of the arsenite — the form official in Fowler's Solution. While arsenic acid is more readily par- taken of by flies, it has the further ad- vantage of being non-poisonous to the hands. — D. II. White arsenic av.oz. y 2 Potassium carbonate av.oz. 2 Sugar av.oz. 8 Water gall. y 2 Mix, dissolve, and saturate paper as in the preceding. III. Arsenic, powder av.oz. 1 Potassium carbonate av.oz. 1 Molasses oz. 2 Water, to make gall. Yz Boil the first two ingredients with a quart of water until they are dissolved, then add the molasses and the remaind- er of the water. Soak sheets of paper in this liquid for 2 or 3 hours, then hang them up to drain and dry. Fly Paper (Bichromate). IV. Posassium bichromate av.oz. 2 Sugar av.oz. 1 Oil of black pepper dr. 4 Alcohol fl.oz. 4 Water fl.oz. 24 Mix thoroughly; macerate for sev- eral days, and filter off the liquid. In this solution soak unsized absorbent paper, allow to dry, and again soak and allow to dry. Fly Paper (Cobalt). V. Tartar emetic gr. 90 Cobalt chlorid av.oz. 1 1088 THE STANDARD FORMULARY Quassia chips av.oz. 8 Tincture of long pepper (i in 4) fl.oz. 8 Water fl.oz. 40 Mix, macerate for 7 days, agitating occasionally, and filter. Prepare the pa- per like the preceding. Fly Paper (Non-Poisonous). As a so-called non-poisonous fly pa- per may be used either the bichromate, cobalt or quassia fly papers. Fly Paper (Quassia), VI. Quassia chips av.oz. 8 Sugar ; av.oz. 4 Water sufficient Pour 32 fluidounces of water over the quassia chips, allow to stand over night, strain and boil the liquid down to 16 fluidounces; then boil the chips with 16 fluidounces of water until 8 fluidounces remain. Mix well together, allow to stand for several days ; filter, soak sheets of absorbent paper in the filtered liquid and drain and dry the paper. VII. Quassia av.oz. 16 Molasses av.oz. 2 l / 2 Distilled water fl.oz. 80 Macerate the wood, in coarse powder, in the water for 24 hours, then boil for one hour, strain, add the molasses and evaporate the whole to 16 fluidounces. Prepare the paper like the preceding. — D. Fly Paper (Sticky). VIII. Rosin av.oz. 6 Lard oil fl.oz. 2 Balsam of fir av.oz. 1 Melt the rosin upon a water bath, add the other ingredients and spread upon paper. The paper should be or- dinary printing paper, which has previ- ously been "sized," by applying a coat- ing of a thin solution of white glue by means of a sponge, and hung uo to dry. The sticky compound is put on whilst warm by means of a brush, and the paper is then folded together. The pro- portion of resin must be varied to suit the changes in the temperature. IX. A good composition is a mix- ture of 2 parts of rosin to 1 of castor oil, melted together, and applied hot with a flat brush to suitable paper. The proportions may be varied according to the nature of the oil or rosin or the time of the year. Fly Pastilles. X. Potassium nitrate, powder, .av.oz. V/2 Mucilage of tragacanth fl.oz. 2 Insect powder av.oz. 2 Althaea, powder dr. 2 Tragacanth, powder dr. 2 Intimately mix the potassium nitrate with the mucilage ; also mix the other ingredients together, then incorporate the powdery mixture with the paste, di- vide the whole into pastilles weighing about 30 grains, and dry at a tempera- ture of 20 to 25 C. The pastilles may be bronzed or gilded, if desired. — D. The fumes of these pastilles when ig- nited in a room will destroy flies and other insects. Fly Pencils. XL Eucalyptol (or oil of eucalyptus) fl.dr. V/z Oil of bay drops 20 Petrolatum av.oz. 2^2 Paraffin wax av.oz. 2 To the paraffin previously melted the oils should be added and the mixture then molded into sticks. — D. This is used for penciling the body exposed to the attacks of flies. XII. Eucalyptol m. 100 Oil of anise m. 25 Paraffin oil fl.oz. 2^ Paraffin wax av.oz. 2V2 Prepare and use like Xo. XL — D. Fly Powders. Good insect powder (pyrethrum) is the best but here are formulas for other powders : XIII. Long pepper av.oz. 4 Quassia .av.oz. 4 Sugar av.oz. 8 Diluted alcohol fl.oz. 4 The solids should be in very fine DOMESTIC UTILITIES. 1089 powder, should be well mixed, and then mixed with the diluted alcohol, dried, and reduced to fine powder. — D. Fly Preventives. XIV. A 20% tincture of insect pow- der in alcohol is recommended for ap- plication to exposed portions of the body to prevent attacks of flies. It is also to be sprayed about the room when mixed with an equal volume of water. — D. XV. Eucalyptol m. 20 Oil of anise m. 20 Camphor gr. 100 Tincture of insect pow- der (20% in alcohol) .. .fl.oz. 4 Use like the preceding. — D. FREEZING MIXTURES. The lowering of temperature pro- duced by the solution of salts has its commonest illustration in the use of a mixture of salt and ice in the freez- ing of ice cream. A temperature of zero is readily obtained. In using freezing mixtures, various salts are used which should be in very fine powder and should be perfectly dry. The vessel should previously be cooled, and cool water should be em- ployed. If the mixture be produced from one salt and water, the former may be recovered by evaporation, and after thorough drying and powdering, it may be used over again. A mix- ture of salts may be recovered in the same manner and used over again. Lowering of temperature by solution of a salt is promoted in many cases to a considerable degree by the pres- ence of a diluted acid. The freezing mixture should be made in a vessel of low conductivity, such as earthenware, while the container of the mixture to be chilled should be as good a con- ductor of heat as possible. I. Ammonium chlorid av.oz. 3 Potassium nitrate av.oz. 1 Potassium chlorid av.oz. 6 Dry each substance and powder, and then to the mixtures add 10 fluidounces of cool water. The temperature depression amounts to 30 C. II. Ammonium chlorid av.oz. 3 Potassium nitrate av.oz. 3 Sodium sulfate, in small crystals , av.oz. 5 Dry the ammonium and potassium nitrate, reduce to powder, add the so- dium sulfate, and then mix with 11 fluidounces of cold water. The temperature depression amounts to 25 C. III. Ammonium nitrate, powder av.oz. 10 Cold water fl.oz. 10 The temperature depression amounts to 30° C. IV. Sulfuric acid, commercial, .fl.oz. 10 Water fl.oz. 5 Sodium sulfate, powder. . .fl.oz. 3 Mix the acid and water, allow the mixture to cool to the temperature of the atmosphere, and add the sodium sul- fate. V. Sodium sulfate av.oz. 8 Hydrochloric acid fl.oz. 5 FROSTING WINDOWS. This is a method used by painters : Put a piece of fresh or soft putty in muslin, twist the fabric tight and tie it in the shape of a pad; clean the glass thoroughly at first, then pat it over with the pad. The putty will exude suffi- ciently through the muslin to. render the stain opaque. Let this stain dry hard and then varnish the glass. If a pattern is required, cut it out in paper as a stencil; place it so as not to slip and proceed as above, removing the stencil when finished. If there should be objection to the clear spaces, they may be covered with slightly opaque varnish. Instead of using a pad, some attach the putty to the tips of their fingers. 1090 THE STANDARD FORMULARY Finer effects are obtained by the use of matt varnishes, hut some skill in their application is required when the glass panes are in position. The prop- er way to employ is to float the varnish over the surface of the leveled pane and then decant off one corner, exactly as photographic plates are handled. In order to obtain a fine grain without streaks, the operation must be done quickly. Here is a formula for matt varnish : Ground-Glass (Matt) Varnish. Mastic av.oz. y 2 Sandarac av.oz. 2 Benzol fl.oz. 10 Ether fl.oz. 20 A solution of guttapercha in chloro- form may be used in a similar manner. FRUIT STAINS, Removal of. See Stains from Fabrics, Removal of. FUNGICIDES FOR PLANTS. The term fungicide signifies an agent to destroy fungi or certain lower forms of parasites. The particular parasites referred to in this connection are such as attack plants, especially fruit trees, for example, blights, rots, smuts, mil- dew, etc. Some of the preparations mentioned under the heading Insecticides for Plants, may also be used as fungi- cides. The formulas and information herein contained are taken from the pamphlet issued by the Department of Agriculture and from other sources of information which may be considered entirely trust- worthy. These fungicides are mostly liouid preparations which are sprayed on the plants. They usually have either cop- per salts or sulfur as a basis. Bordeaux Mixture. This is considered the most valuable fungicide for combating plant diseases. It consists of a mixture of copper sul- fate and lime with water. The formula varies somewhat according to the use which is to be made of the spray. What is called the standard or 6-4-50 formula is as follows : Copper sulfate av.lb. 6 Fresh lime av.lb. & Water, to make gall. 50 Dissolve the copper sulfate in a wood- en or earthen vessel, using 4 or 5 gal- lons of water, which, if hot, will act quicker. In a separate vessel slake the lime and rub until all lumps are broken. Then strain and stir slowly into the copper solution. This is to be dilut- ed and used as soon as possible. The mixture should not stand over 24 hours, as it tends to spoil. Where a good qual- ity of lime is used, 4 pounds will satisfy 6 pounds of copper sulfate. Four ounces of Paris green may be added to each 50 gallons of this liquid for all except peach and other stone fruits, when a combined insecticide and fungicide for general use is wanted. Its chief disadvantage is its spotting the fruit and its liability to be washed off the foliage by rains. For peach and other stone fruits, use only 2 ounces of Paris green. London purple, arsenate of lead, and other arsenicals may be added in the same manner. The above standard Bordeau mixture is frequently slightly modified, a very common modification being this so- called 5-5-50 mixture: Copper sulfate av.lb. 5 Lime av.lb 5 Water, to make gall. 50 This formula is used where it is spe- cially required that there be no excess of the copper salt which will scald the foliage and fruit. For this reason, the 5-5-50 formula is now used for orchard spraying. It has almost replaced stand- ard Bordeaux mixture in spraying for the apple scab, bitter-rot, pear, and cherry leaf blight, and similar diseases. The form of Bordeaux mixture most harmless to foliage is the 3-9-50, which has a considerable excess of lime. This is also called "peach Bordeaux mix- ture." Xo matter what quantity of Bordeaux DOMESTIC UTILITIES. 1091 mixture is made, it will require strain- ing, which is best accomplished by means of a wire strainer. If the milk of lime is strained before mixing with the copper solution, subsequent straining will not be necessary. Various other modifications of the original Bordeaux mixture have been suggested and tried. The principal ones are the "soda Bordeaux mixture" and "potash Bordeaux mixture." The for- mer consists of 6 parts of copper sul- fate, 2 pounds of caustic soda, and 50 gallons of water. The latter has the same amount of caustic potash instead of soda. These alkalies take the place of lime to decompose the copper sul- fate. Other substances have been added to Bordeaux mixture to increase its spread- ing power, especially when the smooth, glossy surface of the fruit and foliage causes the mixture either to collect in drops or run off entirely. Success has been obtained by the use of ordinary hard soap dissolved in hot water and added at the rate of 4 pounds to the barrel of mixture. This is then known as "soap Bordeaux mixture." Instead of hard soap, a saponaceous mixture prepared as follows is also recommended : Rosin av.lb. 5 Potash lye av.lb. 1 Fish oil fl.oz. 16 Water gall. 5 The potash lye is the kind which is ordinarily sold for washing purposes. Dissolve the rosin with the oil in a large iron kettle. Let this cool some- what and then add the potash, slowly stirring the mixture at the same time and watching it carefully to avoid boil- ing over. Then add a portion of the 5 gallons of water and continue boil- ing until the mixture will dissolve in cold water. This will require about an hour, when the remainder of the water should be added slowly and the whole thoroughly stirred. Two gallons of this soap mixture should be added to each 50 gallons of Bordeaux mixture and the whole then strained through a brass wire-cloth strainer. Instead of soap, molasses has been recommended to make the mixture more adherent to fruit and foliage in the following: Copper sulfate av.oz. 6 Fresh lime (or sodium carbonate) av.lb. 4'^ Molasses fl.oz. 32 Water gall. 50 Dissolve the copper sulfate in suf- ficient water, using a non-metallic ves- sel. Slake the lime or dissolve the soda in 2 gallons of water in a separate vessel. Dilute the molasses with a gal- lon of water, and stir it into the lime wash or soda solution. After these have been thoroughly mixed add the whole, with vigorous stirring, to the copper solution. The mixture thus produced should be diluted to 50 gallons and used soon as it deteriorates on standing. It is very adhesive to the foliage, and fewer treatments will be required than when the plain Bordeaux mixture is used. Eau Celeste. Copper sulfate av.lb. 11 Ammonia water pints 11 Water pints 38 Dissolve the copper salt in the water and add the ammonia water. This is however, generally used in a modified form as follows : Copper sulfate av.lb. 4 Sodium carbonate av.lb. 5 Ammonia water pints 3 Water gall. 45 Dissolve the copper sulfate in suffi- cient water, using a non-metallic ves- sel. Dissolve the soda in sufficient water in a separate vessel. Mix these two and then add the ammonia and dilute to 45 gallons. This preparation docs not keep very well. This is a very acrid mixture, and in the hands of careless persons may do much damage to the foliage. It should 1092 THE STANDARD FORMULARY never be used upon the peach, plum or cherry. It gives best results upon the apple. It does not stain the fruit. Ar- senates cannot be safely added to this mixture. Other Copper Solutions. Copper sulfate. — Copper sulfate av.lb. 3 Water gall 50 Dissolve the sulfate in the water. This solution should never be applied to green foliage. Its proper use is as an early spring wash for the trunk and branches of trees and vines to re- move lichens and kill disease spores. 4 or 6 ounces of Paris green may be added to each 50 gallons of the above solution. For stone fruits use only 2 or 3 ounces of Paris green. Copper acetate. — Dibasic acetate of copper, .av.oz. 6 Water gall. 50 Mix and dissolve. This is recommended as an applica- tion to ripening fruit when it is desired to avoid the staining effect of Bordeaux mixture, though it is inferior to the lat- ter as a fungicide. The injurious ef- fect of this solution is much greater than that of Bordeaux mixture and to such susceptible foliage as that of the peach it should be applied sparingly if at all. Ammoniacal copper carbonate. — Copper carbonate av.oz. 5 Ammonia water, con- centrated pints 2 to 3 Water gall. 50 Dilute the ammonia water with about 2 gallons of water. Add water to the carbonate to make a thin paste, pour on about half the diluted ammonia and stir vigorously for several minutes, al- low the mixture to settle and pour off the clear solution, leaving the undis- solved portion of the salt behind. Re- peat this operation, using small portions of the remaining diluted ammonia un- til all the carbonate is dissolved, being careful to use no more ammonia than is necessary to complete solution. Then add the remainder of the water. If kept well corked, this solution will keep a long time. This forms a clear, light-blue solution which, upon drying, leaves little or no stain. As a fungicide it is inferior to Bordeaux mixture and should be used only as a substitute for the latter when the stain of Bordeaux mixture upon ornamental and maturing plants is ob- jectionable. Plants likely to be injured by Bor- deaux mixture will be injured still more by this solution. Examples are the peach, plum and cherry. Arsenites should not be added to this solution. Sometimes 2 pounds ammonium car- bonate dissolved in Y* gallon of water is used in place of the diluted ammonia water in the above. A preparation like this is called "cupram" by the New Jersey Agricul- tural College Experiment Station. As copper carbonate when purchased in the market is quite costly it will be more economical to manufacture it from the cheaper sulfate in the follow- ing manner. Copper sulfate av.oz. 16 Sodium carbonate av.oz. 20 Water sufficient Dissolve each of the salts separately in a gallon of water, pour the two solu- tions together, and stir thoroughly. The precipitate may be collected and then dried or it may be used in the moist condition by being dissolved at once in the ammonia water. The above quanti- ties of salts will make about 8 av. ounces of dried copper carbonate. Corrosive Sublimate Fungicide. For the treatment of the potato scab a solution of corrosive sublimate has given the best results. This is to be prepared by dissolving 1Y2 av. ounces of corrosive sublimate in about \Yz gal- lons of hot water and afterwards add- ing enough water to make 10 gallons. FURS, PRESERVING OF. The following has been suggested for this purpose: DOMESTIC UTILITIES. 1093 fl.dr. 6 fl.dr. 3 fi.dr. 3 m. 30 fl.oz. 32 Carbolic acid... Oil of clove Oil of mibane. Oil of lemon Alcohol, to make Mix and dissolve. The articles are moderately sprinkled with the fluid. One sprinkling will suf- fice for the summer, provided they are stored in closed boxes or closets, but goods in storerooms will require to be sprinkled twice. FURNITURE POLISHES. These occur in three forms, liquids, cream and paste, which contain some similar constituents, varying mostly in consistency. They act by removing dust and dissolving the exterior oxidized coating of varnish, while the friction renews or restores the polish. It fol- lows therefore that the longer and harder the woodwork is rubbed, the better gloss will be obtained. Liquids. These liquid polishes are usually in- compatible mixtures, separating into sev- eral layers, and require to be well agi- tated before use. I. Linseed oil, raw Alcohol, denatured... Diluted acetic acid Oil of turpentine Solution of antimony chlorid fl.oz. 2 II. Linseed oil, raw fl.oz. 40 Diluted acetic acid fl.oz. 16 Alcohol, denatured fl.oz. 4 Solution of antimony chlorid fl.oz. 2 Ammonium chlorid av.oz. 1 Spirit of camphor fl.oz. 1 Add first the antimony solution, then the spirit of camphor and acid, and lastly the ammonium chlorid to the oil, and shake well after each addition. III. Alcohol, denatured fl.oz. to Linseed oil, raw fl.oz. 10 Sandarac dr. 2 Diluted acetic acid... fl.oz. 5 Nitric acid fl.dr. 4 Dissolve the sandarac in the alco- hol and add the other ingredients. fl.oz. 32 ....fl.oz. 8 ....fl.oz. 8 ....fl.oz. 8 IV. Alcohol fl.oz. 1 Acetic acid, 36% fl.oz. 2 Oil of turpentine fl.oz. 4 Linseed oil, boiled fl.oz. 8 Wood or denatured alcohol may be used in place of ordinary alcohol. Creams. V. Potassium carbonate av.oz. 1 Soft or green soap av.oz. 2 Yellow wax av.oz. 8 Water fl.oz. 64 Mix and boil the whole until a uni- form cream results. VI. Yellow wax av.oz. 3^2 Potassium carbonate gr. 160 Oil of turpentine fl.dr. 4 Oil of lavender flowers m. 80 Water sufficient Boil the wax with 16 fluidounces of water over a direct fire, and add to the hot liquid the potassium carbonate. Now remove from the fire, add the two oils, stir until cool, and add enough water to make 32 fluidounces. In using this cream, apply lightly on a woolen cloth, and then rub with a piece of linen until the furniture has acquired a polish. Pastes. VII. Yellow wax av.oz. 4 Alkanet, coarse powder av.oz. y* Oil of turpentine fl.oz. 16 Macerate the alkanet in the oil for 24 hours, strain and add the colature to the wax previously melted. The al- kanet may be omitted, if desired. VIII. Venice turpentine av.oz. 6 Linseed oil fl.oz. 16 Mix by the aid of heat. The mixture may be colored like the preceding by means of alkanet root. IX. Paraffin wax av.oz. 7 Petrolatum, yellow av.oz. 5 Solution of potassa, 5%.... fl.dr. 5 Kerosene fl.oz. 20 Alkanet av.oz. a Heat the potassa with the paraffin and petrolatum, add the alkanet root, 1094 THE STANDARD FORMULARY digest until the liquid is colored suffi- ciently, strain through cloth, and stir in the kerosene while cooling. GASOLINE JELLY OR CREAM. (Solidified Gasoline.) This is the same as Benzin Jelly, but substituting gasoline for the benzine. GELATINIZED BENZIN. See Benzin Jelly. GLASS, MIRRORS, Etc., Polish for. See Window Polishes. GLOVE CLEANERS. For other cleaning preparations, see under headings Benzin Jelly ; Cleansing Preparations ; and Soap, Ox-Gall. These preparations may be in the form of liquids, pastes, or powders. Liquids. Use any of the preparations men- tioned under Cleansing Liquids, which see, or the following: I. Oil of turpentine fl.oz. 5 Benzol fl.oz. 10 II. Chloroform fl.oz. 1 Oil of bergamot fl.dr. 1 Oil of bitter almond drops 5 Oil of clove drops 5 Gasoline, to make fl.oz. 32 This is to be applied with a sponge or soft cloth. Do not use it near any lights or fires or at night. Pastes. III. Solution of chlorinated soda fl.oz. 10 Ammonia water fl.oz. 1 Soap, powder av.oz. 12 Water fl.oz. 16 Make into a soft paste, and rub on the gloves with a flannel. IX. Castile soap, shavings av.oz. 5 Water, hot fl.oz. 5 Solution of chlorinated soda fl.oz. 5 Ammonia water fl.dr. 4 Dissolve the soap in the water, al- low to cool, and incorporate with the solution and ammonia so as to form a smooth paste. In using, rub a small portion over the glove by means of a piece of flannel, always rubbing in one direction until clean. V. Castile soap av.oz. 8 Borax av.oz. 1 Caustic potash av.oz. 1 Glycerin fl.oz. 1 Alcohol fl.oz. 2 Water fl.oz. 42 Oil of mirbane or other essential oil drops 20 Dissolve the borax in 40 fluidounces of water and bring to a boil; during boiling, add the soap, in shavings, and when dissolved add enough water to make up for that lost by evaporation. Dissolve the caustic potash in the re- mainder of the water, add this solution, the glycerin, and the oil dissolved in the alcohol to the soap solution, stirring thoroughly. This mixture may be dis- pensed in tin boxes as a white paste. VI. Curd (tallow) soap av.oz. 4 Saponin dr. 4 Oil of lemon fl.dr. 2 Water fl.oz. 16 Talcum sufficient Dissolve the soap, previously shred- ded, in the water by the aid of heat, then add the saponin and oil and enough talcum to make a stiff paste. A portion of the talcum may be replaced by orris root. If the saponin is considered too expensive, it and the water may be re- placed by a strong decoction of soap bark. The directions for use are : Put the glove upon the hand and apply the paste with a piece of flannel, rubbing the kid from the wrist to the tips of the fin- gers. Powders. VII. White bole (terra alba) parts 5 Magnesium carbonate part 1 When using, make into a paste with gasoline, apply this to the stains of fat or oil, allow to remain until dry, and then remove with a brush. DOMESTIC UTILITIES. 1095 VIII. Terra alba av.oz. 8 Orris root, powder av.oz. A Borax, powder av.oz. 2 Soap, powder av.oz. 1 Ammonium chlorid dr. 2 Mix thoroughly. The directions for use are to dampen the gloves with a wet rag, dust on 'the powder and then rub it well in. When dry, brush off the residual powder. GLUE, BOOKBINDER'S OR TAB- LET. Glue, best av.oz. 7 Glycerin' fl.oz. 16 Water sufficient Pour on the glue more than enough water to cover, allow to macerate for several hours, then decant the greater portion of water; apnly heat until the glue is dissolved, and add the glycerin. If the mixture is too thick, more water may be added. It may be colored by means of an aniline dye dissolved in alcohol. Any of the preparations mentioned under Glues, Liquid, may also be used. GLUE, LIQUID. (Prepared Glue— Syndetikon.) The making of so-called 'liquid glue" depends on the fact that when gelatin or glue is mixed with certain substances in the presence of water, the mixture remains permanently semi-liquid. The most common agents used in this lique- fying process are acetic and nitric acids, lime, chloral hydrate, alkalies, and other substances also being used. The cheaper kinds are made from glue, the handsomer looking prepara- tions from gelatin, but the former prob- ably possess the greater adhesiveness. These preparations are best dispensed in wide-mou^h bottles which are to be kept well-closed when not in use as they will become dry and hard on ex- posure. I. Glue, brown av.oz. 16 Sodium carbonate av.oz. 5^ Water fl.oz. 28 Oil of clove m. 80 I Dissolve the sodium carbonate in the water and add the glue to this solu- tion, allow to stand over night or until the glue has ,become thoroughly soaked and 'swollen, then heat carefully on a water-bath, stirring frequently, until the glue is entirely liquefied, and finally add the oil of clove. The sodium carbonate may be the commercial variety ; the solution in water should then be strained to remove mechanical impurities. White glue may be used instead of the brown but the latter makes the more adhesive glue. The objection to this formula is that in the course of time the alkali will destroy the adhesiveness of the glue. II. Glue av.oz. 10 Nitric acid, ordinary av.oz. 2 Water, to make fl.oz. 20 Soak the glue in 10 fluidounces of water for about 12 hours, then heat carefully on a water-bath, stirring fre- quently meanwhile, and while cooling, gradually incorporate the acid and the remainder of the water. III. Glue, white or brown av.oz. 7 Acetic acid fl.oz. 7 Carbolic add drops 10 Water, to make fl.oz. 20 Soak the glue in 8 ounces of water for 12 hours, then heat by means of water bath until the glue is dissolved, and add to the solution the acids and enough water to make 20 fluidounces. IV. Glue, brown av.oz. 16 Water fl.oz. 24 Carbolic acid, strong fl.oz. 1 Warm the glue with the water on a water bath till dissolved then add the acid, and as much more water as may be necessary to give the proper con- sistency. V. Glue av.oz. 6 Alum dr. 1 Acetic acid fl.oz. 1 109G THE STANDARD FORMULARY Alcohol fl.oz. 3 Water fl.oz. 13 Dissolve the alum in the water, add the glue, macerate the latter till it is softened, then heat carefully on a water bath until the glue is liquefied, allow the mixture to cool somewhat, and then incorporate the acid and alcohol. GLUE, MABINE Macerate 1 to 2 av. ounces of caout- chouc cut into small nieces in 16 fluid- ounces of benzol (not benzin), promot- ing solution by the application of heat and by agitation. To the solution when formed, and which will have the con- sistence of thick cream, add 30 av. ounces of powdered shellac, heat the mixture with constant stirring until complete fusion and combination have been effected. Pour this mixture while hot on plates of metal, so that it may cool in sheets like leather. In using this cement, put some of it into an iron vessel, heat to 120 C, and apply with a brush to the surfaces to be joined. GLUE, STICK. (Pocket Glue— Elas- tic Glue — Mouth Glue — Lip Glue.) See Mucilage, Stick or Bar. GLUE, WATERPROOF. I. India rubber av.oz. Yz Shellac, orange av.oz. 3 Benzol or carbon disulfid. . .fl.oz. 8 Mix and dissolve by agitation. This makes a waterproof joint. II. A waterproof joint may also be made in this wise : Glue , av.oz. 5 Water . .^ fl.oz. 4 1 /' Acetic acid fl.oz. 1 Ammonium bichromate dr. \ l / 2 Soak the glue in 4 fluidounces of wa- ter till soft, then heat on a water-bath till dissolved, incorporate the acetic acid, transfer the solution to a dark amber- colored bottle, and then add the bi- chromate dissolved in the remainder of the water. If an amber bottle is not on hand, the mixture may be kept in an ordinary bottle in a very dark place. In using, apply the glue to the broken ends, fasten the parts together securely, and expose to strong light which makes the glue insoluble. See also under Cements. GOLD, TARNISHED, To Restore. This mixture has been recommended for this purpose: Chlorinated lime dr. 2 Common salt dr. 2 Sodium bicarbonate av.oz. 5 Water fl.oz. 4 Mix well and apply with a soft brush. Only a small quantity is required to ef- fect the purpose. Plain articles may be brightened equal to new by applying a drop of the liquid from the stopper of the bottle and brushing over the sur- face with tissue paper. GOLDWARE, To Clean. See under Gold, Tarnished, To Re- store, and Polishing Powders, or use one of the following: For Goldware. Acetic acid ....'. m. 80 Sulfuric acid m. 80 Oxalic acid gr. 40 Jewelers' rouge gr. 80 Distilled water fl.oz. 16 Mix the acids and water and stir in the rouge, after first rubbing it up with a portion of the liquid. With a clean cloth, wet with this mixture, go well over the article. Rinse off with hot wa- ter and dry. Gilt Bronze Ware. If greasy, wash carefully in suds, or, better, dip into a hot solution of caustic potash, and then wash in suds with a soft rag, and rinse in running water. If not then clean and bright, dip into the following mixture : Xitric acid fl.oz. 3 Aluminum sulfate dr. 2^2 Water fl.oz. 12 Then rirtse in running water. GRAFTING WAX. (Budding Wax.) I. Rosin av.oz. 16 DOMESTIC UTILITIES. 1097 Beef tallow av.oz. r Oil of turpentine fl.dr. 4 Alcohol fl.oz. 5 Melt the rosin, add the tallow, stir until homogeneous, remove from the fire, allow to cool somewhat, and add the oil and alcohol, little by little, stir- ring well with each addition. If in add- ing the alcohol there is a tendency to lump, carefully warm the mixture until it melts. It should be kept in closely stoppered bottles, and when used it should be warmed up slightly. Apply with a brush. A very thin coat only is needed. GREASE ERADICATORS. See under the headings Ammonia, Household; Carpet Cleaners; Cleansing Preparations; Benzin Jelly; Glove Cleaners; Soap, Ox-Gall; and Stains from Fabrics, Removal of. GREASY BOTTLES, TO CLEAN". See Bottles, Cleaning of Greasy. GREASE-PROOF BOXES. The following is the composition of the preparation used for painting the in- terior of cardboard or wooden boxes to make them grease-proof : Fish glue av.oz. 16 Resin av.oz. 2 Litharge av.oz. Yz Glycerin fLoz. ^2 Kaolin av.ozT y 2 Water fl.oz. 40 Boil the glycerin, litharge and part of the water together to dissolve, then mix in the other ingredients. The liquid is applied to the inside of the boxes with a brush and allowed to dry, repeating the application if necessary. GRENADES for Extinguishing Fires. See Fire Extinguishing Hand Gren- ades. GROUND GLASS, Imitation of. A paint for imitating ground glass may be made by rubbing down zinc oxid with linseed oil to a thick cream. Then apply thinly, stippling with a stiff brush. Sugar of lead, ground fine in bleached linseed oil, with a little varnish, well mixed and put on with a stiff brush, will give an imitation that is good enough for many purposes. GUANO, Artificial. Sodium sulfate, dried av.lb. i l / 2 Common salt av.lb. 12 Wood ashes av.lb. 4 Ammonium sulfate, com- mon . „ av.lb. 16 Bone dust bushel 1 GUN BARRELS, Staining of. See Bluing of Gun Barrels, Bronzing of Gun Barrels, and Browning of Gun Barrels. GUTTA PERCHA, Purified. Gutta percha av.oz. 8 Carbon disulfid fl.oz. 38 Alcohol fl.oz. 108 Distilled water fl.oz. 20 Soften the gutta percha in lukewarm water ; then pull to pieces, dissolve it in the carbon disulfid, set the mixture aside for 24 hours, filter through glass wool into a suitable vessel containing 60 fluidounces of alcohol. Agitate the whole together, and set aside until the mixture separates into two layers. De- cant the upper alcoholic layer, wash the residue with the remainder of the alco- hol in the same manner, decant as be- fore; add the water, transfer the mix- ture to a retort, and distil off the carbon disulfid. Owing to the inflammability of the latter, the utmost precaution must be taken to avoid ignition of its vapors. Finally, wash the residual mass by kneading in water, then express the lat- ter, and dry in thin sticks. The product weighs about 5 to &/z av. ounces. Chloroform may be used in place of carbon disulfid, but 80 fluidounces will be required. The chloroformic solution will mix with the alcohol and the latter will not separate until the addition of water. HAND GRANADES. See Fire Extinguishing Hand Gren- ades. 1098 THE STANDARD FORMULARY HANDS, To Remove Stains From. See Stains from the Hands, To Re- move. HARNESS BLACKING AND POL- ISH. The preparations mentioned under Shoe Blacking will serve for blackening and polishing harness, or use one of the following : I. Lampblack av.oz. % Bone black av.oz. i% Yellow wax av.oz. 6 Oil of turpentine fl.oz. 60 Beat the two blacks with about an ounce of the oil to make a smooth paste; also melt the wax at a gentle heat, add the remainder of the oil, and then incorporate the previously prepared paste. — H. II. Shelhic, bleached av.oz. 4 Borax av.oz. 2 Sugar av.oz. 4 Nigrosin av.oz. 1 Water fl.oz. 27 Heat the borax and shellac with the water on a water bath until the shellac is dissolved, adding ^water from time to time to replace that lost by evaporation ; then add the sugar and nigrosin, stir until dissolved, and then add enough water to make 40 fluidounces. — D. In using the harness or other leather goods should be thoroughly cleaned by washing with soap and water, allowed to dry, and then coated with this dress- ing by means of a brush or sponge. HARNESS DRESSING OR OIL. See also the similar preparations un- der the heading Shoe Grease. If these preparations are intended for yellow (not blackened) leather, the lampblack is to be omitted. I. This has been called Government Harness Dressing. Bayberry wax av.lb. I Yellow wax av.lb. 1 Beef tallow av.lb. 1 Castor oil pint 1 Neatsfoot oil pints 4 Lampblack av.oz. ]/ 2 Melt the two waxes together, add the oils, and incorporate the lampblack. II. Neatsfoot oil fl.oz. 20 Oil of turpentine fl.oz. 4 Petrolatum av.oz. 8 Lampblack av.oz. 1 Make a smooth mixture of the lamp- black with the oil of turpentine, melt the petrolatum, add the neatsfoot oil, and shake with the first mixture. HARNESS-MAKER'S WAX. See Shoe and Harness Makers' Wax. HARNESS VARNISH or Lacquer. I. Shellac av.oz. 2 Sandarac av.oz. l /2 Mastic dr. 2 • Venice turpentine av.oz. V/z Alcohol or wood alcohol. . .fl.oz. 24 Aniline black dr. 2 Mix, dissolve by agitation, and strain. More aniline black may be added if a darker shade is desired. II. . Shellac av.oz. 6 Gum turpentine av.oz. 6 Venice turpentine av.oz. 1 Sweet oil fl.oz. 1 Lampblack av.oz. 1 Alcohol or wood alcohol. . .fl.oz. 32 Dissolve the first three ingredients in the alcohol by agitation, strain, and add the lampblack previously rubbed to a perfectly smooth paste with the oil. This mixture is to be well shaken be- fore using. III. Rosin av.oz. 1 Thick turpentine av.oz. 1 Sandarac av.oz. 2 Shellac av.oz. 4 Oil of turpentine fl.oz. 1 Alcohol or wood alcohol. . .fl.oz. 36 Lampblack av.oz. 1 Mix all but the lampblack and oil, agitate frequently until dissolved, rub the lampblack to a smooth mixture with the oil, and incorporate with the alco- holic solution. HATS, To Clean. See under Panama Hats, To Clean, and Straw Hat Cleaners. DOMESTIC UTILITIES. 1099 HEEL BALL. This is described as the best formula : Beeswax av.oz. 16 Suet av.oz. 4 Ivory black av.oz. 4 Lampblack av.oz. 2 Gum arabic av.oz. 2 Rock candy av.oz. 2 The gum arabic and rock candy should be in very fine powder. Melt the wax and suet, stir in the finely powdered ivory black, sifted lampblack, and the rock candy and gum arabic, mix the whole thoroughly, allow to cool some- what, and pour into tin or leaden molds. HECTOGRAPH MASSES OR PADS. Hectographs, also known as copying pads, copygrams, copygraphs, chromo- graphs, collographs, etc., are employed for the purpose of duplicating writing by taking an impression of writing made with a suitable aniline ink on a receiving pad made essentially from gelatin or glue and glycerin and then obtaining copies by laying fresh sheets of paper upon the pad. The following formula will make a srood pad. The directions with regard to air bubbles, pouring of the mass, etc., must be followed strictly in the succeed- ing formulas: Take a pound, or any convenient quantity of pure white glue, free from whiting or other insoluble matter, and macerate in water, until it becomes soft and pliable. With a little manipulation and turning, this may be accomplished by using a pint of water for each pound of glue. Drain off the excess of water, if there be any, and add glycerin in the quantity of from two to three pints for each pound of glue used. The lesser amount is for summer, and the larger amount for winter use. Heat the mix- ture gently until the glue is dissolved, and the water absorbed by the glue has evaporated. The easiest way of ascer- taining when this is accomplished is to take the weight of the evaporating dish out before commencing; then when the weight of the dish and its contents is equal to its tare and the amounts of glue and glycerin used, the operation may be considered completed. If the water is not driven off, the pad is likely to crack in a dry atmosphere by its spontaneous evaporation. It will be found somewhat trouble- some to avoid air bubbles in the mass. They may be avoided to an extent by the use of only moderate heat in dis- solving the glue. When bubbles have formed, they may be skimmed off, but it is easier to destroy them by the use of alcohol. The mass when finished is strained into a wide mouthed bottle and allowed to stand in a warm place, or in warm water for an hour or two, when most of the bubbles will have arisen to the top and formed a scum on the sur- face. A small quantity of alcohol is now poured carefully down the side of the bottle, which instantly destroys them all. The gelatin, which is precipitated by the alcohol on the surface, redis- solves as the alcohol evaporates. When this has occurred, the mass may be poured into a suitable shallow tray, holding the mouth of the bottle as near the tray as possible, to avoid the forma- tion of fresh bubbles. The tray may be made by any tinner and should be as large as the largest paper on which copies are to be taken. It should be about V2 inch deep. To secure firmness, it should be fastened to a board. The melted mass may now be poured, as de- scribed, to nearly fill the tray; any air bubble which forms must be removed with a hot wire or other suitable means, and when cold the pad or hectograph is ready for use. It is difficult to obtain a pad absolute- ly free from bubbles and one which is not sticky. To avoid the latter, various insoluble powders, sometimes soluble salts, are added to the hectograph mass. The former include clay, chalk, sulfur, barium sulfate, etc. ; the latter potassium and other chromates. The former must be rubbed to a smooth paste with a por- 1100 THE STANDARD FORMULARY tion of the melted mass before adding to the remainder of the mass ; the lat- ter must be dissolved in the smallest amount of water before adding to the remainder of the mixture. The modus operandi of taking copies is as follows : Write upon well-glazed paper with a suitable ink, using a new, broad-pointed pen, allow it to remain for a minute or so to dry partially, then invert carefully upon the pad and press evenly and uni- formly. In a minute or two sufficient ink will have been absorbed by the pad from the paper so that new sheets of paper (not so well glazed), pressed upon the pad, will receive duplicates of the original writing. The number of copies that may be taken in this way, as well as their distinctness, varies accord- ing to the pad and the ink. The original writing, if laid upon a fresh pad or a fresh portion of the same pad after tak- ing the first imprint, will furnish still other copies. After all the copies are taken, the pad should be cleansed with a moist sponge, after which it should be dried. A trifling amount of ink will re- main in the* pad, but this will not inter- fere with subsequent operations. The copies are sometimes improved by moist- ening the copying paper with water or strong alcohol, and then absorbing the excess of liquid between folds of bibu- lous paper. Hectograph inks are mentioned under heading Inks. The hectograph mass, instead of being poured into a tray, may be formed into a roller by casting in a mold. Copies may be taken by passing the roller over the writing and then over the paper to receive the copies. The following mixtures may be form- ed into hectograph pads, as described above : I. Gelatin av.oz. 4' Glycerin fl.oz. 30 Potassium bichromate dr. 1 II. Gelatin av.oz. 4 Water _ fl.oz. 15 Glycerin fl.oz. 15 White clay (kaolin) av.oz. 2 III. Gelatin av.oz. 1 Molasses av.oz. 1 Glycerin fl.oz. 9 Water sufficient IV. Glue av.oz. 7 Glycerin fl.oz. 30 Carbolic acid fl.dr. 4 Sulfur dr. 1 The glue should be soaked in water several hours before it is melted with the glycerin. Barium sulfate is also used as an addition. V. White glue av.oz. 6 Glycerin fl.oz. 32 Dextrin av.oz. 2 Precipitated sulfur av.oz. ^2 Water sufficient VI. The following is said to be the formula of the French Ministry of Pub- lic Works : Glue av.oz. 4 Glycerin av.oz. 20 Water fl.oz. 15 Kaolin or barium sulfate, in fine powder av.oz. 1 Soak the glue in the water until it takes up as much moisture as it will absorb. Drain and press out the sur- plus and place the container with the glue in a water bath. Heat until solu- tion takes place. In the meantime mix the barium sulfate or kaolin with the glycerin and add to the hot solution of glue. Maintain the heat for a few hours, in order to drive off the excess of water, and pour the mixture into a shallow tin or zinc tray. HECTOGRAPH SHEETS. A variation of the hectograph pads are the sheets prepared as follows : Macerate 4 parts of good white glue in a mixture of 5 parts of water and 3 parts of ammonia water until the glue is soft. Warm the mixture untii the DOMESTIC UTILITIES. 1101 glue is dissolved, add 3 parts of granu- lated sugar and 8 of glycerin, stir well, and let the mixture come to a boil. While hot, paint the liquid upon white blotting paper with a broad brush until the paper is thoroughly soaked and a thin coating remains upon the surface. Allow it to dry for 2 or 3 days, and it is then ready for use. Use the regular hectograph ink for writing and before transferring the latter to the blotting paper, wet the latter with a dampened sponge and wait a minute or two before using. Then proceed to make copies in the ordinary way. If the sheets are laid aside for 2 or 3 days, the writing sinks in and does not require to be washed -off. HORN AND IVORY, To Color Black. First place the horn in an aqueous solution of a lead salt, with a slight ex- cess of sodium hydrate. The duration of this treatment depends on the char- acter of the horn and the strength of the solution — generally half an hour is sufficient. Then wash well and intro- duce the horn into a solution of 350 grains of wool black and 18 grains of naphthol yellow S in 1 pint of water at 40 C. A longer subjection to this lat- ter treatment appears to be necessary. For bone and ivory, water-soluble nigrosin will answer. It is only neces- sary to lay the pieces, oreviously de- prived of fat and mordanted, in a hot aqueous solution of nigrosin until the desired tone is obtained. On account of its cartilaginous components, ivory can- not be boiled in the nigrosin solution, but the same result can be obtained by allowing it to stand for some hours in a concentrated solution at a temperature of about 30 C. To deprive the bones of fat before treatment with aniline colors it is suffi- cient to boil them with frequent changes of water, subsequent treatment with ether being unnecessary. Kellermann's method of mordanting is especially recommended. This con- sists of placing the defatted bones for 15 minutes in the following: Nitric acid fl.oz. 1 Water fl.oz. 21 Tartaric acid dr. 2 They are then washed and placed in a solution of 7 grains of zinc chlorid in 1 pint of water with a few drops of hy- drochloric acid. With ivory it is sufficient to mordant for 15 minutes in 1% hydrochloric acid. HYDROGRAPHIC PAPER. I. Black: Nutgall, very fine powder dr. 4 Ferrous sulfate, dried, very fine powder dr. 1 Rub this mixture over the surface of paper with pressure, brushing off the loose portions. This writes black with a pen dipped in water. • II. Blue (No. 1) : Monsel's salt, very fine powder. dr. 1 Potassium ferrocyanide dr. 2 Prepare the paper as in the preceding. This writes blue with water. III. Blue (No. 2) : Wet paper with a weak (colorless) solution of potassium ferrocyanide and dry. Write upon it with a colorless so- lution of Monsel's salt or a very dilute solution of iron subsulfate. It writes blue. IV. Reddish brown: Copper sulfate, very fine powder dr. 1 Prussian blue, very fine powder dr. 2 Proceed as in I and II. It writes reddish brown with water. HYPODERMIC SYRINGES, To Clean. The following is from a medical au- thority: If the wire cannot be passed through the canal, hold the needle for a moment over a flame, the foreign sub- stances being rapidly destroyed and driven off, then pass the wire through. If a wire has been rusted into the needle, the latter should be dipped in oil before holding over the flame. To re- 1102 THE STANDARD FORMULARY move rust from the interior of the can- ula, oil should be passed through the latter, then heating as before. Finally rinse out the needle with alcohol. INCENSE. (Balsamic Fumigation.) I. Benzoin av.oz. 2 Olibanum av.oz. 3 Myrrh av.oz. 3 Cascarilla av.oz. i l / 2 Oil of lavender flowers .... drops 5 Oil of bergamot drops 10 Oil of clove drops 5 Oil of cinnamon drops 4 II. Olibanum av.oz. 7 Benzoin av.oz. 2 Cascarilla av.oz. 1 INKS, Manufacture of. The characteristics of a good writing ink are as follows : 1. It must flow easily from the pen, but not drop from it nor spread on the paper. 2. It should not contain finely sus- pended matter which will subside in the course of time, but should be perfect so- lution. 3. The color should be dark, and therefore practically saturated, and writ- ing made with it should not fade. 4. It should not mold, nor be liable to other decomposition. 5. It should copy or it should not, as may be desired, and, 6. It should not appreciably attack or corrode steel pens. Black writing inks are frequently classed according to their use, as fol- lows : 1. Office or document inks, which must be prepared from nutgall or tan- nin, should be permanent, and are in- tended for documents which are to be preserved. 2. Copying inks, which are prepared from nutgall, tannin, logwood, or even coal tar dyes, and which must furnish good copies, and 3- Ordinary writing inks, such as are employed as house and school inks, and which should be cheap and from which no special permanence is expected. According to composition, inks may be classified into 1. Aniline inks. 2. Logwood inks. 3. Xutgall inks. 4. Tannin inks, and 5. Miscellaneous inks. The first class yields copying and writing inks, as well as the various col- ored inks which are in use for various purposes. The second class yields copy- ing and writing inks, and the third and fourth classes yield document and copy- ing inks. The fifth class embraces hec- tograph inks, indelible inks, sympathetic inks, etc. Formerly it was customary to aad acetic acid and acetates, oxalic acid and oxalates, nitric acid and nitrates, tar- trates, sodium chlorid, ammonium chlor- id, potassium chlorate, copper sulfate or acetate, alum, or even logwood to nut- gall inks, but these not only serve no good purpose but are even harmful. In order that a good ink may retain its excellent qualities, certain cautions should be observed in its use : Before putting a new ink in an ink-well, the old ink should be entirely removed and the ink-well washed. Also no ink container should be used which cannot be closed, and such ink vessel should always be closed when not in use. If an ink is liable to thickening or other change, the ink-well should be cleansed before re- filling, even if with the same ink. Several preparations, which are used in the manufacture of many of the inks which follow, are mentioned here. Xutgall infusion: Chinese nutgall av.oz. 6^2 Talcum, purified av.oz. Y\ Water, distilled sufficient Reduce the nutgall to coarse powder, moisten (not wet) the powder, and set the latter aside at a temperature of 20 to 25 C. until it is thickly covered with mold. In order to hasten this molding, the drug should be moistened daily with water, so that it will always have about the same proportion of moisture. At DOMESTIC UTILITIES. 1103 the end of from 8 to 10 days, fermenta- tion will have advanced sufficiently to admit of extraction of the drug. To the latter should be added 13 fluidounces of water, and the mixture heated for an hour on the water-bath. Then express, treat the residue in the same manner with the same amount of water, and then again with 7 fluidounces of water. Mix the three liquids obtained, add the talcum, shake well, set aside for 24 hours, filter, and add enough water, if necessary, through the filter to make the filtrate measure 32 fluidounces. The solution will keep for several days. The fermentation causes the conver- sion of a portion of the tannin in the galls into gallic acid, which results in an ink superior to one containing tannin only. Chinese galls are preferred to oak galls because of the larger amount of extractive matter. Tannin solution: Tannic acid av.oz. 3 Muriatic acid, commercial. . .fl.dr. 4 Distilled water sufficient Mix the two acids and -3 fluidounces of water in a flask, and heat on a water bath to a temperature of 80 to 90 C. for 3 hours, adding from time to' time hot water until 27 fluidounces are added. This solution should not be kept long- er than 7 days. Aniline Inks. — Many of the coal-tar dyes (misnamed "anilines") which are now manufactured, produce excellent copying inks. Compared to nutgall, tan- nin, and logwood inks, they are less per- manent, but they will serve excellently where no especial permanence is re- quired. They are especially useful as hectograph inks. Where permanence of writing is demanded, as in the draught- ing of documents, aniline inks cannot be employed, as they soon become bleached from the action of air and light. It is to be noted here that water con- taining lime decomposes many aniline colors, and solutions of these dyes in calcareous water may thicken in the course of time, hence only distilled wa- ter should be employed in the manufac- ture of these inks. In making, only the best obtainable dye of the kind mentioned should be used, as otherwise good results cannot be obtained. Logwood Inks.— These might also be designated as chrome inks, for they al- ways contain potassium bichromate or chrome alum; also some acid, with the object of producing acid salts of the chromium compound. The greater the amount of acid in proportion to the chromium, the paler or redder and thin- ner the product, and, conversely, the. greater the proportion of chromium, the darker and thicker the ink will be. Most logwood inks copy with great facility- writing produced sometimes being copy- able even after weeks and months. Logwood inks can be more easily erased from paper than nutgall inks. They have the advantage of furnishing several copies if desired. All inks lose their copying qualities when exposed to air containing even traces of ammonia. In order to facilitate copying with an exposed logwood ink, the copying paper should be moistened with a 1/10% aque- ous solution of potassium chromate. Old writing made with logwood ink may be copied in the same manner, even after the lapse of years. Logwood inks may be prepared from the following solution : Logwood extract solution: Logwood extract, best. .. .av.oz. 4^2 Distilled water fl.oz. 20 Dissolve the extract in the water on a water-bath, set the solution aside for 8 days, and decant the clear liquid. Nutgall Copying Inks. — Copying inks differ from non-copying in that they re- tain their copying qualities. Inks which are made with ferric salts soon become non-copyable, while those made with ferrous salts, especially ferrous sulfate, copy the best. Hence copying inks are made with ferrous salts, and non-copy- 110-J THE STANDARD FORMULARY ing inks with ferric salts. The copying qualities of ink are improved by the ad- dition of pure sugar or of glucose. In preparing the different nutgall copy- ing inks, the following mixture, which may be known as Nutgall Ink Body I, forms the basic ingredient : Nutgall Ink Body I: Xutgall infusion (see above) fl.oz. 30 Sulfuric acid, concentrated. . . .m. 40 Ferrous sulfate, pure av.oz. 2 Distilled water sufficient Mix the infusion and acid; heat for 15 minutes on a water bath, dissolve the iron salt in the mixture, transfer the latter to a bottle, cork well, set aside for 2 weeks, filter and add through the filter enough water to make the filtrate meas- ure 32 fluidounces. Nutgall Non-Copying Inks. — The fol- lowing mixture, known in these pages as Nutgall Ink Body II, serves as a body for many of the inks mentioned below : Nutgall Ink Body II: Nutgall infusion (see above) fl.oz. 32 Solution of chlorid of iron, U. S. P fl.oz. 2^2 All on this mixture to stand for 2 weeks in a closed vessel, and then filter. Tannin Copying Inks. — Tannin copy- ing inks, like the nutgall copying inks, are preferably made with ferrous salts and contain an addition of sugar or glu- cose. The following mixture, which may be known as "tannin ink body I," is the basic ingredient of the tannin copying inks : Tannin Ink Body I: Tannin solution fl.oz. 15 Ferrous sulfate, pure av.oz. 1^4 Distilled water sufficient Heat the tannin solution to about 70 or 8o° C.j also dissolve the iron salt in 9 fluidounces of hot water; mix the hot solutions by pouring iron solution grad- ually into the tannin solution, set the mixture aside for 3 weeks, filter and add enough water through the filter to make the filtrate measure 25 fluidounces. Tannin Non-Copying Inks. — The tan- nin inks herein mentioned are frequent- ly prepared by the use of the following mixture, which may conveniently be termed "tannin ink body II" : Tannin Ink Body IT. Tannic acid av.oz. 2 l A Solution of iron chlorid, U. S. P fl.oz. 5 Muriatic acid, commercial. . .fl. dr. 2 Water sufficient Heat the two acids, the solution and 3 z /2 fluidounces of water in a flask on a water-bath, to a temperature of 80 to 90 C, for a period of 10 hours. Then add 20 fluidounces of hot water; continue the heat for another hour, transfer to a bottle, cork well, set aside in a cool place for 2 weeks, filter and add through the filter enough water to make the fil- trate measure 32 fluidounces. Alizarin Ink. Alizarin paste gr. 225 Sodium carbonate, pure gr. 105 Extract of logwood gr. 375 Carbolic acid fl.dr. 2 Water fl.oz. 32 Dissolve the sodium carbonate in a small amount of water, add the alizarin paste, then the extract of logwood pre- viously dissolved, in the remainder of the water. Filter and transfer the liquor to a rather large bottle, drop in a few nails or iron filings, and expose the whole to the sunlight for a week, with occasional agitation. Lastly, decant and preserve by incorporating the carbolic acid. This ink does not corrode the pen, is not affected by light, and does not gum, but it is not acid proof. Alizarin Ink (Copying). 1/2 1 3 3^ Indigotin dr. Aniline green D dr. Sugar av.oz Distilled water fl.oz. Nutgall ink body I fl.oz. Carbolic acid drops 20 Dissolve the dyes and sugar in the water by the aid of heat, add the re- maining ingredients, transfer the mix- ture to a bottle; tie over the latter » DOMESTIC UTILITIES. 1105 oiece of paper, set aside in a cool place for a week, and decant the clear liquid from the trifling precipitate. II. Indigotin gr. 70 Aniline green D gr. 40 Glucose av.oz. 1 % Distilled water fl.oz. 2 Tannin ink body I fl.oz. 25 Carbolic acid drops 15 Dissolve the dyes and glucose in the water by the aid of heat, add the re- maining ingredients, transfer to a bot- tle; tie over the latter a piece of paper, set aside in a cool place for one week, and decant the clear liquid from the trifling precipitate. Alizarin Ink (Non-Copying). I. Aniline green D gr. 75 Indigotin dr. 2 Water fl.oz. 28 Nutgall ink body II fl.oz. 38 Carbolic acid m. 30 Dissolve the two dyes in the water by the aid of heat, add the other ingredi- ents, transfer the mixture to a bottle, tie over the mouth of the latter a piece of paper, set aside for one week in a cool place, and decant the clear liquid from the trifling sediment. II Indigotin gr. 80 Aniline green D .gr. 50 Tannin ink body II fl.oz. 16 Distilled water fl.oz. 25 Carbolic acid drops 20 Sugar gr. 40 Dissolve the dyes in the water by the aid of heat, add the other ingredients, transfer to a bottle, tie over the latter a piece of paper, set aside for one week in a cool place, and decant the clear liquid from the trifling precipitate. Black Ink (Copying). I. Phenol black B (coal-tar dye) dr. 3 Sugar av.oz. 1^4 Distilled water fl.oz. 3 Nutgall ink body I fl.oz. 32 Carbolic acid drops 20 Prepare like alizarin copying ink No. I. II. Phenol black B (coal-tar dye) dr. 2 l / 2 Glucose av.oz. 1 l / A Distilled water fl.oz. 2 Tannin ink body I fl.oz. 25 Carbolic acid .-.drops 15 Prepare like alizarin copying ink No. II. III. Aleppo galls (free from in- sect perforations) av.oz. $ l / 2 Clove dr. 1 Distilled water fl.oz. 40 Ferrous sulfate, pure dr. 12 Sulfuric acid, pure. m. 35 Neutral sulfate of indigo dr. 2 The galls and cloves, coarsely ground, may be extracted by percolation with water until 40 fluidounces are obtained, or they may be macerated with sufficient water. In either case it is intended to produce 4*0 fluidounces of the fluid, and allowance must be made for the water absorbed by the marc. To this, when filtered, add the iron, and when dis- solved filter again, then add the acid and, after mixing thoroughly, the indigo paste, after which it may be again fil- tered. If the ink is intended to be non-copy- ing, only 4>2 ounces of galls should be used. This produces a blue-black fluid, not apt to mold. To insure a superior prod- uct, careful attention must be paid to manipulation, details, and to the quality of its ingredients. The galls must be free from insect perforations, and the iron in selected crystals free from efflor- escence or ferric salt, and the indigo be neutral, or nearly so. If the article sold as "indigo paste" is not at hand, it may be prepared by carefully adding to the ordinary sulfate of indigo a solution of potassic or sodic carbonate until effer- vescence ceases. This is said to be the formula used by a large firm in England. IV. Extract of logwood av.oz. 3 Potassium bichromate dr. 3 Hydrochloric acid fl.oz. 1 HOG THE STANDARD FORMULARY Sugar av.oz. 8 Gum arabic, whole av.oz. 2 Water, to make gall. 1 Dissolve the extract and bichromate each in 3 pints of water by the aid of heat, mix the solutions, add the acid, then incorporate the gum and sugar previously dissolved in 2 pints of water. Black Ink (Non-Copying). I. Phenol black B (coal-tar dye) gr. 320 Water fl.oz. 28 Nutgall ink body II fl.oz. 38 Carbolic acid m. 30 Prepare like alizarin non-copying ink, No. I. II. Phenol black B (coal-tar dye) gr. 160 Tannin ink body II fl.oz. 16 Distilled water fl.oz. 25 Carbolic acid drops 20 Sugar gr. 40 Prepare like alizarin non-copying ink, No. II. III. Extract of logwood av.oz. 7 Lime water fl.oz. 50 Carbolic acid fl.dr. 2 Muriatic acid fl.oz. i l / 2 Mucilage of acacia fl.oz. 5 Potassium bichromate gr. 90 Water, to make ..fl.oz. 112 Dissolve the extract in the lime water on a water-bath, stirring constantly, and then add the two acids, which change the color of the solution from red to brownish yellow. Set the mixture aside until cool, then filter; add the potassium salt, first dis- solved in some water, and finally, the remainder of the water. I. Black Ink (Writing). Logwood extract solution. av.oz. 20 Potassium bichromate gr. 90 Chrome alum av.oz. 5 Oxalic acid av.oz. 1 Carbolic acid fl.dr. 1 Distilled water sufficient Mix the extract solution with 50 fluid- ounces of water, heat on a water-bath to 90 C. add the potassium bichromate, chrome alum, and oxalic acid previously dissolved in 15 fluidounces of water ','• continue the temperature of 90 C. for Yi hour, then add enough water to make the mixture weigh 100 av. ounces, and I the carbolic acid; set aside for 2 or 3 days, and decant the clear liquid. This ink is black in color, and the writing is of the same tint. It is very cheap, and hence is adapted to school purposes. II. Phenol black B (coal-tar dye) av.oz. 2 Sugar av.oz. 2 Carbolic acid fl.dr. 1 Sulfuric acid, pure m. 20 Distilled water fl.oz. 90 Mix the dye with 6 fluidounces of cold water, allow to stand for 2 hours, then add the remainder of the water, in the boiling condition, and the other ingredi- ents, and stir about until dissolved. This ink writes a handsome blue -black. For school purposes it may be cheap- ened by reducing the dye even to 1^ av. ounces. III. This is said to be a formula in use in Denmark for records and impor- tant documents. It is an excellent for- mula : Tannin dr. Gallic acid dr. Acacia dr. Ferrous sulfate, pure av.oz. Carbolic acid m. Hydrochloric acid fl.dr. Water, to maker fl.oz. Dissolve the tannin and gallic acid in a portion of the water, the ferrous sul- fate in another portion, the acacia in a third portion, mix the three solutions, and add the acids. IV. This formula is quite different from any of the others: Tannic acid dr. Ferrous sulfate dr. Iron lactate dr. Tartaric acid dr. Pyrogallic acid gr. Pyoktanin gr. Mucilage of acacia dr. Water, warm fl.oz. Mix all the ingredients, except 6 2 4 1 20 2 35 4 4 4 4 15 15 6 48 the DOMESTIC UTILITIES. 1107 mucilage, shake well to dissolve the sol- ids, set aside for a few days, agitating occasionally, strain, and add the muci- lage. V. This makes a cheap but not dura- ble ink for school use. Bismarck brown gr. 8 Methyl violet gr. 12 Bengal green gr. 20 Gum arabic dr. 2 Water fl.oz. 16 Mix and dissolve. The first three in- gredients are coal tar or so-called aniline dyes. "Brilliant green" may be used in- stead of Bengal green. Black Ink (for Fountain Pens). Decoction of galls (from 6 ozs.) fl.oz. 32 Solution of ferric chlorid. .fl.oz. 3^2 Phenol blue FFF (coal-tar dye) . ^ dr. 1 Carbolic acid m. 20 Distilled water fl.oz. 16 Mix the decoction and iron solution in a closed bottle, allow to stand for 2 weeks, filter, in the filtrate dissolve the dye by the aid of heat, and add the acid and water. Allow to stand for a week longer in a cool and dark place, and de- cant from any sediment which may have formed. Blue Ink (Copying). Phenol blue 3 F (coal-tar dye) gr. 50 Sugar av.oz. 1 Y\ Distilled water fl.oz. 3 Nutgall ink body I fl.oz. 32 Carbolic acid drops 20 Prepare like alizarin copying ink No. I. II. Phenol blue 3 F (coal-tar dye) gr. 45 Glucose av.oz. i l /i Distilled v/ater fl.oz. 2 Tannin ink body I fl.oz. 25 Carbolic acid drops 15 Prepare like alizarin copying ink No. I. III. A blue copying ink that may be used without a press, by merely placing the letter between the leaves of the book and closing it energetically, is prepared according to this formula : 70 I. Aniline blue av.oz. 1 Alum av.oz. l / 2 Glycerin fl.oz. 24 Water fl.oz. 64 Instead of the aniline blue, any other water-soluble aniline may be used. Dis- solve this in the water, add the alum, dissolve it, and then incorporate the glycerin. Blue Ink (Non-Copying). Phenol blue 3 F (coal-tar dye) ' gr. 100 Water fl.oz. 28 Nutgall ink bodv II fl.oz. 38 Carbolic acid m. 30 Prepare like alizarin non-copving ink, No. I. II. Phenol blue 3 F (coal-tar dye) dr. 1 Tannin ink body II fl.oz. 16 Distilled water fl.oz. 25 Carbolic acid drops 20 Sugar gr. 40 Prepare like alizarin non-copving ink, No. II. I. Blue Ink (Writing). Resorcin blue M (coal-tar dye) gr. 50 Sugar gr. 200 Oxalic acid gr. 10 Distilled water fl.oz. 20 Mix the dye with 1 fluidounce of cold water, set aside for 2 hours, then add the remainder of the water, in the hot condition, and the other ingredients, and stir about until dissolved. This ink writes a handsome blue and flows readily, but has the disadvantage of somewhat corroding the pen, and hence the latter should be cleaned fre- quently. Brown Ink. Catechu av.oz. 1 Water, warm fl.oz. 16 Potassium bichromate solu- tion, 10% sufficient Dissolve the catechu in the water, fil- ter, and add enough of the bichromate solution to impart the proper color. 1108 THE STANDARD FORMULARY Eosin Ink. (Scarlet Ink — Coral Ink.) I. Eosin A, yellowish av.oz. Y2 Sugar av.oz. 1 Distilled water fl.oz. 32 Mix the dye with 1 fluidounce of cold water, set aside for 2 hours, add the re- mainder of the w r ater, in the hot condi- tion, and the sugar, and stir until dis- solved. There are various shades of eosin, so that it will be necessary to obtain just the right kind. II. Eosin (water-soluble) dr. 2 Alcohol fl.oz. 2 Mucilage of acacia fl.oz. 1 Water, to make fl.oz. 16 Dissolve the eosin in about 12 fluid- ounces of water, a small portion of this being poured hot upon the eosin con- tained in a bottle ; next add the alcohol, and shake ; finally, add the mucilage and enough water to make 16 fluidounces. Glossy Inks. Ink may be made glossy by the addi- tion of mucilage of gum arabic or of a solution prepared by heating a mixture of borax, 45 grains; shellac, 15 grains; sugar, 30 grains, and water, 4 fluid- ounces. See also Mourning Ink. Gold Ink. I. This may be prepared by mixing equal parts of potassium iodid and lead acetate, placing them upon a filter, and then pouring on twenty times the quan- tity of boiling distilled water. As the filtrate cools the lead iodid separates in golden scales. After the filtrate has cooled the precipitate should be collected on a filter, washed with a little cold wa- ter, and rubbed up to an ink with muci- lage of acacia. The ink must be shaken before using. II. Reduce gold foil to powder by triturating in a mortar with honey or syrup, dilute with water, decant the li- quid, wash the gold several times with water ; dry and mix with mucilage of acacia. Green Ink (Copying). I. Aniline green D dr. 2 Sugar av.oz. Ij4 Distilled water fl.oz. 3 Xutgall ink body I fl.oz. 32 Carbolic acid drops 20 Prepare like alizarin copying ink,, Xo. I. II. Aniline green D gr. 70 Glucose av.oz. 1% Distilled water fl.oz. 2 Tannin ink body I fl.oz. 25 Carbolic acid drops 15 Prepare like alizarin copving ink, Xo. II. Green Ink (Non-Copying). I. Aniline green D gr. 200 Water fl.oz. 28 Xutgall ink body II fl.oz. 38 Carbolic acid m. 30 Prepare like alizarin non-copving ink Xo. I. II. Aniline green D gr. 100 Tannin ink body II fl.oz. 16 Distilled water fl.oz. 25 Carbolic acid drops 20 Sugar gr. 40 Prepare like alizarin non-copying ink Xo. II. Green Ink (Writing). Methyl green, bluish (water soluble) gr. 96 Sugar gr. 192 Distilled water fl.oz. 20 Mix the dye with 1 fluidounce of cold water, set aside for 2 hours, then add the remainder of the water, in the hot con- dition, and the sugar, and stir about un- til dissolved. Mourning Ink. This is a deep black, shiny ink used by bereaved relatives to notify friends and ether relatives of their loss. A satisfac- tory formula is said to be the following : Borax, powder av.oz. 1 Shellac, orange av.oz. 3 Water, boiling fl.oz. 16 Lampblack '..... sufficient Dissolve the borax in the water and in this solution dissolve the shellac, aiding DOMESTIC UTILITIES. 1109 the process by constant stirring and the application of some heat. Rub up a small quantity of the lampblack with sufficient of the liquid to form a paste, and adding more and more liquid until a suitable ink is obtained. Orange Ink. Aniline orange av.oz. ^ Sugar av.oz. I Distilled water fl.oz. 32 Mix the dye with i^ fluidounces of water, set aside for 2 hours ; then add the sugar and the remainder of the wa- ter, in the hot condition, and stir until dissolved. Purple Ink. Aniline purple -.--. gr. 80 Alcohol fl.dr. 12 Mucilage of acacia fl.dr. 10 Water fl.oz. 17 Dissolve the dye in the alcohol and then add the other ingredients. This color is brilliant at first, but is liable to fade. Red Ink (Aniline). See Eosin Ink. A red, inclining to purple may also be made by dissolving fuchsin (ordinary aniline red) in water in the proportion of about 2 drams to the pint. Solution may be more readily effected by first dissolving the color in a little alcohol (about 5 fluidrams), and then adding the water. A small proportion of gum arabic is sometimes added to give the ink more "body." Two drams to the pint is sufficient. Another good formula is the follow- ing: Erythrosin ; . . . gr. 75 Water fl.oz. 16 Thicken with gum arabic, and add a little boric acid or other preservative. I. Red Ink (Carmine). Carmine gr. 192 Ammonium carbonate gr. 192 Ammonia water fl.oz. 4 Mucilage of acacia fl.oz. 3 Distilled water fl.oz. 13 Mix the carmine and ammonium car- bonate, dissolve in the ammonia water, and add the remaining ingredients. II. Carmine gr. 128 Ammonia water fl.oz. 8 Distilled water fl.oz. 8 Gum arabic av.oz. Y\ Dissolve the carmine in the ammonia water, add the distilled water and gum, and dissolve the latter by agitation. Red Ink (Cochineal). Cochineal, powder av.oz. V/z Potassium carbonate av.oz. 3 Cream of tartar av.oz. 9 Potassa alum dr. 4^4 Mucilage of acacia fl.oz. 3 Alcohol fl.oz. i}/ 2 Oil of clove drops 20 Distilled water fl.oz. 29 Macerate the cochineal and potassium carbonate with 25 fluidounces of water in a flask for 2 days; then add the cream of tartar and alum, heat on a water bath until all the carbonic acid gas is expelled, add the alcohol and filter. Wash the filter with 2 fluidounces of water, and to the filtrate add the mucilage and the oil. Writing done with cochineal ink is very permanent. Red Ink (Copying). I. Ponceau R R (coal tar dye) . .dr. 2^ Sugar av.oz. l 1 /^ Distilled water fl.oz. 3 Nutgall ink body I fl.oz. 32 Carbolic acid drops 20 Prepare like alizarin copying ink No. I. II. Ponceau R R (coal tar dye) . .dr. 2 Glucose av.oz. 1% Distilled water fl.oz. 2 Tannin ink body I fl.oz. 25 Carbolic acid drops 15 Prepare like alizarin copying ink No. II. Red Ink (Non-Copying). I. Ponceau R R (coal tar dye) .gr. 192 Water fl.oz. 28 Nutgall ink i body II fl.oz. 38 Carbolic acid m. 30 Piepare like alizarin non-copying ink No. I. 1110 THE STANDARD FORMULARY II. Ponceau R R (coal tar dye) .gr. ioo Tannin ink body II fl.oz. 16 Distilled water fl.oz. 25 Carbolic acid gr. 20 Sugar gr. 40 Prepare like alizarin non-copying ink No. II. Scarlet Ink. The so-called scarlet inks are usually the same as the eosin inks. Silver Ink. This may be prepared from silver leaf by a process similar to making gold ink from gold leaf. Vanadium Ink. Vanadium tannate was first proposed for use as a writing ink by Berzelius, because the writing is not affected by acids, but the high price of vanadium salts was a great obstacle to its intro- duction. Since these salts have been more largely prepared for use in the manufacture of aniline black and other dyes, vanadium ink has again been pro- posed. The following formula may be used: Tannic acid : . . . . av.oz. 1 Ammonium vanadium gr. 18 Water fl.oz. 10 Dissolve the acid in 9 fluidounces of water and the vanadium in 1 fluidounce of water, and mix the solutions. This ink flows with a deep-black color from the pen, without spreading or striking through the paper, although it contains no gum. It has a nice gloss, cannot be copied, dries quickly, and, even if the writing is laid in water for 24 hours, does not change its black color. It is very useful for writing addresses of letters, postal cards, etc., when used fresh. Dilute acids do not alter it, but solutions of chlorinated potassa (or soda) bleach it completely. After a few weeks the tint of the ink begins to change, writing executed with it becomes lighter and somewhat yellow- ish, and in about 3 months the change is completed, when it has a fox-yellow tint. The writing is still plainly legible, however, and cannot be removed either by water or by acids. Violet Ink (Copying). I. Phenol blue 3 F (coal tar dye) gr. 40 Ponceau R R (coal tar dye) . .dr. 1 Sugar av.oz. 1 l /i Distilled water fl.oz. 3 Nutgall ink body I fl.oz. 32 Carbolic acid drops 20 Prepare like alizarin copying ink No. I. II. Methyl violet 3 B (coal tar dye) gr. 100 Sugar gr. 100 Oxalic acid gr. 20 Distilled water fl.oz. 20 Dissolve the dye by the aid of heat in the water, add the other ingredients. and again dissolve. Violet Ink (Non-Copying). Phenol blue 3 F (coal tar dye) gr. 45 Ponceau R R (coal tar dye) . .dr. 1 Water fl.oz. 28 Xutgall ink body II fl.oz. 38 Carbolic acid m. 30 Prepare like alizarin non-copying ink No. I. II. Phenol blue 3 F (coal tar dye) gr. 30 Ponceau R R (coal tar dye).gr. 40 Tannin ink body II fl.oz. 16 Distilled water fl.oz. 25 Carbolic acid drops 20 Sugar gr. 40 Prepare like alizarin non-copying ink Xo. II. Violet Ink (Writing). Methyl violet 3 B (coal tar dye) > gr. 90 Sugar gr. 90 Oxalic acid gr. 20 Distilled water fl.oz. 20 Mix the dye with 1 fluidounce of cold water, set aside for 2 hours, then add the remainder of the water, in the hot condition, and the other ingred- ients, and stir until dissolved. White Ink. White inks, for writing on colored DOMESTIC UTILITIES. 1111 surfaces, consist either of a white min- eral suspended in a viscid medium, or of chemicals affecting the coloring in the paper. This, in the case of ultra- marin, is an oxalic acid solution, or hydrochloric acid, according to this f ormute : Ink for Blue Paper. Hydrochloric acid fl.dr. I Mucilage m. 30 Water fl.dr. 7 To produce white writing on photo- graphs, iodin is employed, as in the next formula : Ink for Silver Prints.. Iodin gr. 15 Acacia gr. 15 Potassium iodid gr. 150 Water fl.oz. 1 For preparations of the first order take lightest zinc oxid, or lead or mag- nesium carbonate, or freshly precipi- tated barium sulfate, or starch (all in an impalpable powder) and suspend in a diluted solution of gum arabic, dex- trin, or tragacanth. The mixture re- quires shaking from time to time to keep the pigments from separating. The "ink" may be preserved by addition of oil of clove or other antiseptic to pre- vent decomposition of the mucilage. HECTOGRAPH INKS. (Chromogra- phic Inks.) These are inks which are used in connection with hectographs (see Hect- ographs Masses or Pads). As will be observed they are made with coal tar, or the so-called aniline dyes. Hectograph Ink (Black). Dissolve nigrosin in water in the pro- portion of 1 of the former to 5 or 7 of the latter. Or use the following : Nigrosin, deep-black E gr. 30 Methyl violet gr. 10 Gum arabic gr. 8 Glycerin fl.dr. 3 Alcohol ...fl.dr. 6 Dissolve the dyes in the alcohol, the gum in the glycerin, and mix the solu- tions. Hectograph Ink (Blue). Resorcin blue M dr. 1 Glycerin m. 30 Alcohol fl.dr. 1 Acetic acid, glacial drops 8 Distilled water fl.oz. 1 Dissolve the dye in a mixture of the other ingredients by the aid of heat. Hectograph Ink (Green). I. Aniline green D dr. 2 Acetic acid, glacial drops 6 Glycerin m. 30 Alcohol fl.dr. 1 Distilled water oz. 1 Dissolve the dye in a mixture of the other ingredients by the aid of heat. II. Aniline blue, water- soluble ■■.'... dr. 1 Picric acid dr. 1 Glycerin dr. 1 Alcohol fl.dr. 3 Water fl.dr. 3 Dissolve the solids in the mixed li- quids contained in a flask by the aid of a N gentle heat. Hectograph Ink (Red). I. Eosin, ff 40 dr. 3 Distilled water fl.dr. 6 l / 2 Glycerin m. 30 Dissolve the dye in the mixed liquids. Hectograph Ink (Violet). Violet ink for hectographic purposes is the most popular as it furnishes the largest number of satisfactory copies. I. Methyl violet 3 B gr. 50 Alcohol fl.dr. 1 Distilled water fl.oz. 1 Dissolve the methyl violet in the al- cohol and water by the aid of gentle heat. II. Violet aniline dr. 2 Alcohol fl.dr. 1 Acetic acid, diluted fl.dr. 1 Water fl.dr. 7 Dissolve by trituration. I'll. Violet aniline ST. 40 Alcohol fl.dr. 2 1112 THE STANDARD FORMULARY Glycerin fl.dr. I Water fl.dr. 2 Dissolve by trituration. MARKING INKS. (Laundry Ink.) These are the inks intended for mark- ing clothes prior to passing them through the laundry. Most of them are made with silver salts as a basis. In order to distinguish from brand- ing inks, read article under Branding Inks. See also Indelible Inks. Marking Ink (Black). I. Silver nitrate av.oz. 5 Gum arabic av.oz. 3 Ammonia water fl.oz. 12 Lampblack dr. 3 Dissolve the silver nitrate and gum arabic in the ammonia water, by fre- quent agitation in a dark amber bottle, then incorporate the lampblack with this solution by trituration. In using, write with a quill pen, allow the writing to dry, then pass a hot iron over it. If the quantity of gum be increased to 5 -fluidounces, the ink may be spread on a plate of glass and a rubber stamp may then be used to apply it. When the mark is dry, it should be ironed as in the preceding case. II. This is Woodhouse's indelible ink. Silver nitrate dr. 4 Infusion of nutgall fl.dr. 1 Acacia dr. 1 Distilled water fl.oz. 4 Dissolve the silver nitrate in 4 fluid- ounces of water. In the remainder of the water dissolve the acacia and add the infusion. Then mix the two liquids. The infusion of nutgall should be made by pouring 4 fluidrams of boiling dis- tilled water upon 15 grains of powdered nutgall. III. Asphalt, in pieces av.oz. 2 Benzol fl.oz. 8 Coal tar av.oz. 8 Dissolve the asphalt in the benzol and add the coal tar. In 'using the ink, employ an ordinary pen, and if it should be too thick, thin it with a little oil of turpentine. This ink does not spread, and reouires no heating. It never fades, and it is not affected by anything. IV. The indelibility of this ink de- pends on the fact that when potassium bichromate and gelatin come together, particularly in the form of a thin film, in the presence of daylight, the film becomes insoluble in hot or cold water. Gelatin gr. 16 Potassium bichromate gr. 16 Nigrosin gr. 80 Water fl.oz. 8 Dissolve the gelatin and the nigrosin in most of the water, and the potassium bichromate in the -remainder. Mix the two solutions in an amber-colored bottle. If it is found that the ink "gums" in the pen, the quantity of gelatin and bichromate may be somewhat reduced. The ink, when properly made, cannot be entirely removed by hot or cold water, acids or alkalies. Marking Ink (Blue). V. Silver nitrate dr. 4 Stronger ammonia water. . .fl.dr. 12 Sodium carbonate, crystal dr. 4 Copper sulfate dr. 2 Mucilage of acacia fl.oz. 2 Distilled water, to make .... fl.oz. 4 Dissolve the silver salt in the am- monia, and the soda and copper salt in a portion of the water; mix the two solutions and add the mucilage and the remainder of the water. If the ammonia water mentioned above is insufficient for solution, more should be added. Marking Ink (Red, Crimson or Car- mine). VI. Silver nitrate av.oz. 1 Sodium carbonate, pure crystals av.oz. i l / 2 Tartaric acid gr. r6o Stronger ammonia water, .fl.oz. 2 Carmine gr. 6 Sugar av.oz. Vz Gum arabic av.oz. _ V 2 Distilled water sufficient Dissolve the silver nitrate and so- DOMESTIC UTILITIES. 1113 dium carbonate separately in 16 fluid- ounces of distilled water, and mix the solutions. Wash the precipitate by de- cantation with 32 fluidounces of water three times ; collect on a filter, and wash with 4 ounces of water; drain well; transfer the precipitate to a mortar and rub up with the tartaric acid ; when ef- fervescence ceases, add the ammonia (in which the carmine has been dis- solved), then the sugar and gum (pre- viously made into a cream with water). Finally, make up to 6 fluidounces with distilled water. VII. The following makes a pur- plish red color and is reasonably per- manent, but it is a complicated process. First prepare a solution composed of Sodium carbonate, pure crystals dr. 3 Gum arabic dr. 3 Water fl.oz. 12 With this moisten the spot to be marked, and dry and smooth with a hot flat iron. Then on the prepared spot write with a solution of 1 dram of platinic chlorid in 2 fluidounces of water, allow the writing to dry, and then apply a liquid compound of 2 drams o£ tin chlorid and 1 fluidounce of water. Marking Ink, Gold. VIII. (A). Chlorid of gold and sodium gr. 30 Distilled water fl.dr. 5 Gum arabic dr. 1 (B). Oxalic acid gr. 6o Water fl.dr. 5 Gum arabic dr. 2 Moisten the goods with B, allow to dry, then write upon the prepared sur- face with A. A quill pen is to be pre- ferred. After writing pass a hot iron heavily over the mark. Marking Ink, Osmium. IX. Use a solution of osmic acid in water, one in fifty; the marks will soon assume an intense dark blue color. The fabric must previously be sized, with mucilage for example, and ironed. X. Marking Ink, Platinum. Platinum chlorid. gr. 18 Water fl.dr. 3 Mucilage of acacia, sufficient to make ink flow properly. The portion of the fabric to be mark- ed must previously be treated with a small amount of solution of stannous chlorid and mucilage of acacia. After writing, the fabric should be eently heated when the marks will assume a black or blackish color. INKS, MISCELLANEOUS. A variety of inks and ink products, or preparations known as "inks," but which are not writing inks are mentioned un- der this heading. Branding Ink. By this is meant a liquid used for marking boxes, bales, packages, etc., by means of a small brush. They are fre- quently termed marking inks, and are also used for stenciling purposes. I. Shellac av.oz. 2 Borax av.oz. 2 Gum arabic av.oz. 2 Water fl.oz. 25 Pigment sufficient Boil the borax and shellac in the water until they are dissolved, add the gum arabic and allow to cool. Add water to complete 25 fluidounces and then stir in the pigment, using either Venetian red, lampblack, ultramarine, or Prussian blue. Black is improved by the addition of blue. Green may be pro- duced from a mixture of blue and chrome yellow. II. Rub lampblack, gum arabic, and some fine clay together like pipe clay or fuller's earth, and then mix with water to suitable consistence. Lamp- black imparts the color, clay the body and the gum the adhesiveness. Any other gummy substances such as dex- trin may be used as the adhesive. The color may be varied as in the case 0/ I No. I. 11U THE STANDARD FORMULARY TIL Mix boiled linseed oil with suf- ficient lampblack. IV. Another good preparation is as- phaltum varnish thinned suitably with oil of turpentine, and then adding a small amount of lampblack or other black pigment. Chinese Ink. See India Ink. Diamond Ink. This is a liquid used for etching glass. Commercial strong hydrofluoric acid often gives negative results, be- cause when applied in its pure state, it produces such a smooth corrosion of the glass that it may elude superficial inspection. The most common method consists in mixing ammonium fluorid with precipitated barium sulfate and decomposing with sulfuric acid, and is as follows: I. Ammonium fluorid av.oz. i Barium sulfate av.oz. 3 Sulfuric acid sufficient Rub the two solids together, transfer to a platinum, lead or gutta-percha ves sel, and add sufficient sulfuric acid to produce a cream-like paste. Operators must be cautioned against inhaling the exceedingly acrid vapors of hydroflouric acid. Apply with a quill or camel's-hair pencil. II. Ammonium fluorid av.oz. 2 Barium sulfate av.oz. 2 Hydrofluoric acid, fuming. sufficient Mix the two salts in a porcelain mor- tar, transfer to a platinum or lead ves- sel, and by means of a platinum wire stir in enough of the acid to make a thin paste. Writing may be performed with a steel pen, allow it to remain for one- half hour, and then wash off with wa- ter. To make etching more visible, rub in a little printer's ink. III. Sodium fluorid gr. 75 Potassium sulfate gr. 15 Water fl.oz. 3 Make a solution and label A. Zinc chlorid gr. 45 Hydrochloric acid dr. 2 Water fl.oz. 3 Make a solution and label B. In using, mix equal quantities of the solutions in a gutta-percha or leather vessel, or in a glass vessel the interior of which has been covered with a layer of paraffin, or in a hollow in a piece of paraffin wax. Drawing Ink. Use either Endorsing Ink, Enamel Ink, or Indestructible Ink for Glass, which see. Enamel Ink. An ink, or rather varnish, for writing labels which are intended to resist the action of acids, etc., may be prepared as follows : Shellac av.oz. 1 Borax av.oz. 1 ^2 Xigrosin (water-soluble) . .av.oz. ^2 Tannic acid ". gr. 15 Picric acid gr. 5 Ammonia water .fl.dr. 12 Water sufficient Dissolve the shellac and borax in 15 to 20 fluidounces of water by the aid of heat, and filter hot; to the filtrate add the nigrosin, acids and ammonia, and then enough water to reduce the mix- ture to the required dilution. The ink should be of such consistence that it will readily flow from the pen. Endorsing Ink. Shellac Borax Water Mucilage of acacia.... Boil the first three together for a short time, filter, add the mucilage, and to the mixture add enough lampblack or powdered indigo or a mixture of the two to bring it to the required shade. The ink dries with a glossy surface and is practically indestructible. Indelible Inks. All the inks under the heading of Inks, Marking, are indelible and are in- tended for marking clothes. There are also a number of the formulas under the title of Stamping Inks which are in- av.oz. 2 av.oz. 1 .fl.oz. 18 .fl.oz. 2/2 DOMESTIC UTILITIES. 1115 delible and which differ from the mark- ing inks only in the fact that the former are applied with a pen and the latter "with a stamp. Indestructible Ink for Deeds, Etc. Use either Endorsing Ink, which see, or the following : Oil of lavender fl.oz. i Gum copal fl.dr. I Lampblack gr. 10 Indigo gr. 2 Dissolve the gum in the oil by the aid of a gentle heat, then thoroughly incor- porate the pigments which must have been rubbed to an impalpable powder. Indestructible Ink for Writing on Glass. Labels on bottles containing solution's of various chemical substances are often attacked by the latter, and in a short time become illegible. In such cases it is advisable to write on the glass direct- ly with an ink that is not affected by chemical substances. Such an ink is made according to the following for- mula: Shellac dr. 2^ Alcohol fl.oz. 2>4 Borax dr 4^ Distilled water fl.oz. 4 Methyl violet gr. 10 The shellac is dissolved in the alcohol, and the borax in the water. The alco- holic solution, previously slightly warm- ed, is then added to the borax solution, little by little, and as soon as the two solutions are thoroughly mixed the methyl violet is added. Bottles and other vessels marked with this ink can be readily cleaned with a damp cloth without causing the slightest injury to the label. Lithograph Ink. The following formulas are used: I. Yellow wax av.oz. 10 Shellac av.oz. 8 Mastic av.oz. 5 Tallow av.oz. 4 Tallow or curd soap av.oz. 4' Venice turpentine av.oz. J^ Lampblack av.oz. 2Y2 Mix all but the lampblack by fusion and then thoroughly incorporate the lat- ter. II. Shellac av.oz. 6 Mastic av.oz. 4 Venice turpentine av.oz. Y2. Yellow wax av.oz. 8 Tallow av.oz. 3 Lampblack av.oz. s l / 2 Prepare like the preceding. India Ink. (Chinese Ink.) The following processes are said to be used: Rub lampblack to a paste with a very weak liquor potassa, and diffuse through water made slightly alkaline with the potassa. Then collect the pig- ment, wash it with water, and dry it. The dry powder is then to be levigated to a smooth stiff paste with a strong fil- tered decoction of Irish moss or quince seed, a few drops of essence of musk and about half as much essence of am- bergris being added towards the end of the process. The moss is then molded, dried, and ornamented with Chinese characters. Another process is this : Boil a weak solution of fine gelatin in a Papin's di- gester for 2 hours, then in an open ves- sel for one hour filter the liquid, evapo- rate it to proper consistency, either in a steam or salt water bath, and make into a paste as before with pure lampblack which has previously been heated to dull redness in a crucible. Invisible Inks (Sympathetic, Fading, Vanishing or Diplomatic Inks). Invisible or sympathetic inks are fluids used for writing purposes, the charac- ters made with them being invisible, but becoming visible upon the application of heat or of some suitable reagent. "Writ- ing made with those inks which becomes visible upon the application of heat, again becomes invisible upon cooling; on the contraiy, writing developed by chem- ical action remains permanent. I. Cobalt chlorid dr. 3 Glvcerin fl.dr. 1 Water r ^-oz. 4 Mix and dissolve the ingredients. 1116 THE STANDARD FORMULARY The characters traced with this ink become blue on gently heating the paper. II. Linseed oil m. 30 Ammonia water fl.oz. 1 Water fl.oz. 5 To make the writing or the drawing appear which has been made upon paper with the ink, it is sufficient to dip it into water. On drying, the traces disappear again, and reappear by each succeeding immersion. The mixture must be agitated each time before the pen is dipped into it, as a little of the oil may separate and float on top, which would, of course, leave an oily stain upon the paper. III. Write with tincture of iron chlor- id diluted with 10 parts of water, and develop with a blotter moistened with a solution of tannin or decoction of nut- galls or strong tea. This may be reversed by writing with a decoction of nutgalls and developing with the blotter moistened with tincture of iron. Label Ink, Waterproof. Use either Enamel Ink or Indestructi- ble Ink for Glass, which see. Mimeograph Ink. Boiled linseed oil av.lb. 2 Lampblack av.lb. 1 Indigo dr. 3 Prussian blue dr. 3 Use the oil hot and incorporate the solids, making a thoroughly smooth mixture. The lampblack and indigo should both be of the very best quality. The mixture is to be thinned to the de- sired consistency with a mixture of equal parts of oil of turpentine and ligroine. Persian Ink. This is a lasting ink which is a sort of compromise between Indian or Chi- nese ink and the iron inks of the west- ern world. It is as follows : Lampblack part 1 Iron sulfate part 1 Xutgall parts 2 Gum arabic, purest parts 4 Reduce the substances to the finest powder, mix intimately and then on a tile or stone work up, adding water, at first in small amount at a time, until the mass is homogenous, when it may be added more freely. The amount of water added is according to the use to which the ink is to be put. Shading-Pen Ink. This may be made by rubbing up solu- ble blue with a thin mucilage of acacia and adding some glycerin. A black ink may be made by rubbing up lampblack in the same manner. Inks of other col- ors may be made by using various ani- lines dyes. The so-called stamping inks may be used as shading-pen inks. Shoe-Finisher's Ink. See under the regular heading of Shoe-Finisher's Ink. Show-Card Ink. I. A common method of making an ink for show-card purposes is to dis- solve a teaspoonful of some aniline dye in a pint of water by the aid of heat, in this solution dissolving an ounce of yellow dextrin to give body to the ink. II. Another formula is the follow- ing: Shellac, bleached av.oz. . 2 Borax, crystal av.oz. 1 Water fl.oz. 16 Rub up the shellac and borax together in a mortar until reduced to a fine pow- der ; then place the mixture in an enam- eled iron vessel and add the water; ap- ply heat, and boil the whole together until the mixture begins to foam when it is removed from the fire and allowed to cool. The boiling process is to be repeated until all of the shellac is finally dissolved. When cold the solution is to be strained through fine cheesecloth, and constitutes the vehicle for the pigment, sufficient Frankfort black or lampblack being stirred in, together with a little finely powdered indigo, to produce a bluish or jet-black color. A variety of colored inks may be made by the addition of various pig- DOMESTIC UTILITIES. 1117 ments. A thoroughly smooth mixture should be made of the pigment with the liquid. If a glossy ink is desired, yellow dex- trin should be added in the proportion of i to 4 av. ounces of dextrin to 16 fluidounces of ink. III. This makes a good black show- card ink: Asphaltum av.oz. 4 Venice turpentine av.oz. 2 Lampblack av.oz. 1 Oil of turpentine fl.oz. 16 Dissolve the asphaltum and Venice turpentine in the oil and with this solu- tion thoroughly incorporate the lamp- black. Stamping Inks. (Rubber Stamp Inks.) These inks are generally used for stamping impressions (printing, etc.) on paper. They are made with glycerin as a vehicle and a water-soluble coal-tar color (so-called "aniline dye") imparts the color. Dextrin may be added to in- crease the "body" or density of the mix- ture. These inks must be perfectly smooth and the dye thoroughly dis- solved to make a nice, clean impression. These inks are used for rubber stamps, as oily inks speedily decompose rubber. The following is a good example. See also Inks, Stamping (for use with metal stamps). I. Aniline blue, water-soluble, I B '. av.oz. Y\ Yellow dextrin av.oz. 2^ Distilled water fl.oz. 2^2 Glycerin fl.oz. 14 Mix the dye and dextrin, dissolve by the aid of a water bath in the water, add the glycerin, and replace the water lost by evaporation. — D. Other colors are produced by substi- tuting for the blue dye any one of the following : Violet — Methyl violet B av.oz. H Red — Diamond fuchsin I... av.oz. Y? Or Eosin B B N av.oz. # Yellowish green — Methyl green av.oz. 1 Brown — Vesuvin B Black— Phenol black B. .av.oz. 1% .av.oz. Y\ — D. II. Another good formula is this: Nigrosin av.oz. y 2 Water fl.oz. 2^/2 Alcohol fl.oz. 2>4 Glycerin fl.oz. 12 Dissolve the nigrosin in the alcohol, add the other ingredients, and make a perfectly smooth mixture. This ink is thinner than the preceding and owing to the presence of alcohol dries more quickly. Nigrosin is a coal-tar dye, of which there are several varieties which differ in solubility. III. Borax av.oz. 1 Shellac, bleached av.oz. 1 Mucilage of acacia fl.oz. 1 Ultramarine blue ....av.oz. to 1 Water, Glycerin, of each sufficient Dissolve the borax in 10 fluidounces of water, heat to boiling, add the shel- lac, and dissolve. Now triturate the mucilage with the ultramarine, add this to the shellac solution, and then enough of equal parts of water and glycerin to make 12 fluidounces. IV. Take of the finest quality of lampblack and rub into a smooth paste with a sufficient quantity of glycerin; or take a good black printer's ink and thin the same with kerosene. Formulas I and II are most satisfac- tory. Stamping Ink. (For Use with Metal Stamps.) Rubber-stamp inks usually have glyce- rin as a vehicle; metal-stamp inks may have oil or glycerin as a vehicle, and hence the preceding rubber-stamp inks may be used as metal-stamp inks, or the formulas given below may be used. The formulas mentioned are of two varie- ties, one containing the coloring matter in suspension, the other in solution. In either case a perfectly smooth mixture must be made. 1118 THE STANDARD FORMULARY I. Mixture of pigments with oil: A. Ultramarine blue: Ultramarine blue av.oz. I Olive oil fl.oz. 3 Mix intimately. B. Dark blue : Prussian blue av.oz. y 2 Ultramarine blue. av.oz. Y\ Olive oil fl.oz. 4 Prepare like the preceding. The Prus- sian blue alone does not mix readily with oil, and hence the ultramarine is added. C. Green : Verdigris av.oz. 2 x / 2 Oleic acid, crude fl.oz. Y? Olive oil fl.oz. 7 Prepare like the preceding. D. Red: Cinnabar or vermillion av.oz. 4 Olive oil fl.oz. 6 Prepare like the preceding. E. Black: Gas carbon or lampblack. . .av.oz. 1^ Olive oil fl.oz. 8^ — D. II. Solution of dye in oil: Anilines or coal-tar dyes for this pur- pose must be the kind known as oil-sol- uble. In preparing these inks, rub the dye with the oleic acid to perfect smoothness, then add the oil, little by little, with constant rubbing. After in- corporating all of the oil, heat the mix- ture under constant stirring to about 45 C. until the dye is completely dissolved. While olive oil is not a drying oil, the oleic acid causes it to be absorbed •by paper and thus prevent rubbing. A. Red: Bordeaux red aniline gr. 75 Scarlet red aniline gr. 75 Oleic acid, crude fl.dr. 5 Castor oil fl.oz. 10 Prepare as described above. B. Blue: Aniline blue dr. 2 l / 2 Oleic acid, crude fl.dr. 5 Castor oil fl.oz. 10 Prepare like the preceding. C. Violet: Aniline violet dr. 2 x k Oleic acid, crude fl.dr. 5 Castor oil fl.oz. 10 Prepare like the preceding. D. Black: Aniline black dr. Oleic acid, crude fl.dr. Castor oil fl.oz. Prepare like the preceding. E. Green : Aniline blue dr. Aniline lemon yellow gr. Oleic acid, crude fl.dr. Castor oil fl.oz. Prepare like the preceding. — All from D. Stencil Inks. These are the same as Branding Inks, which see. Sympathetic Inks. See Invisible Inks. Typewriter Ink. Typewriter ink is of two kinds, one being made with petrolatum and lamp- black or similar pigment, the other with glycerin and alcohol and aniline color. The former is to be used if a permanent record is desired. In making the first kind, put some best-quality petrolatum into a suitable vessel, and melt it by placing the ve? sel on a fire ; then put as much lamp- black or bone black as the petrolatum will take up without becoming granu- lar. To effect this incorporation the black pigment should be put in a little at a time, and the whole thoroughly stirred while making the additions. Be careful not to let the petrolatum be in excess, as it will cause the print to have a greasy outline ; while on the other hand, if the pigment be in excess, the print will not be clear. Ordinary bone black does not make a good product ; purified animal charcoal will do better. If the petrolatum is too soft, add a small amount of yellow wax. When a proper mixture of petrolat- um and pigment has been made, remove the vessel from the fire, and while it is cooling mix equal parts of petrolatum, benzin and oil of turpentine, and in this mixture put the black petrolatum com- pound, mixing in a little of the other, with constant stirring, so as to effect a thorough combination, and the petro- DOMESTIC UTILITIES. 1119 latum compound becomes "dissolved. The quantity of the volatile solvent should be sufficient to render the fluid ink of the consistence of oil paint ; the result will be a good, permanent black ink, which will not be rubbed off with water like aniline inks. For colored inks of this class use Prussian blue, red led, chrome yellow ; and for inks of the aniline class use these dyes dissolved in equal parts of alcohol and glycerin; thus, for a black aniline ink dissolve one-half av. ounce of aniline black in 13 fluidounces alcohol, and then add the glycerin. Ink the ribbon in the us- ual way. Having prepared the ink, proceed to ink the ribbon; the secret of success lies in the proper application of the ink to the ribbon. Thus : wind the ribbon on a piece of cardboard, spread on a table several layers of newspapers, then unwind the ribbon in such lengths as may be most convenient, and lay it flat on the naper ; apply the ink, after well shaking it, by means of a soft brush, and rub it well into the interstices of the ribbon with a toothbrush. Hardlv any ink should remain visible on the surface. For inking typewriter ribbons the fol- lowing process is also recommended : Into 2 fluidounces of any aniline writing ink ->ut a teaspoonful of mucilage of acacia, and a teaspoonful of brown su- gar, warm the mixture, and immerse the ribbon from the typewriter long enough for it to become well saturated. When dry, spread the ribbon on a board and brush it well with glycerin. Should there be too much color in the ribbon, press it out between absorbent papers with a warm flatiron; or if too dry, brush it again with glycerin. The secret of the ribbon giving out its color is the glycerin, and if there is body enough in the color there is no danger that it cannot be made to work well. A ribbon so prepared is not af- fected by the dryness or humidity of the atmosphere. It is necessary that the ribbon should retain a certain degree of moisture, for the gum and sugar make it dry and harsh, so the glycerin coating is put on ; but there is danger of smearing the paper with too much moisture, or caus- ing a wrinkled surface, and the ironing obviates this. Users of the typewriter should so set a fresh ribbon as to start at the edge nearest the operator, allowing it to run back and forth with the same adjust- ment until exhausted along that strip; then shift the ribbon forward with the width of one letter, running until ex- hausted, and so on. Finally, when the whole ribbon is exhausted the color will have been equally used up, and on re- inking the work will appear even in color, while it will look patchy if some of the old ink has been left here and there, and fresh ink applied over it. The following formula may also be used to make a typewriter ink: Transparent soap av.oz. 1 Glycerin fl.oz. 4 Water fl.oz. 12 Alcohol fl.oz. 24 Aniline color sufficient Dissolve the soap in the water and glycerin by the aid of heat; dissolve the aniline color in the alcohol and mix the solution. If the ink is too soft, add more soap. For' the aniline color, use any suit- able coal tar dye. Ink for Writing on Celluloid. The following is recommended : Iron chlorid, dry dr. 3 Tannin dr. 4 T 4 Acetone fl.oz. 4 Dissolve the chlorid and tannin each in a portion of the acetone, then mix the solutions. Any pen may be used with this liquid. Do not write on visible parts of the ob- ject as the ink is difficult to remove. Ink for Writing on Photographs. The following produces an ink serv- iceable for marking "proofs;*" the writ- ing being done on a dark portion, the 1120 PHE STANDARD FORMULARY lines soon, bleach by the conversion of the silver into an iodid : Potassium iodid av.oz. I Iodin gr. 45 Gum arabic gr. 45 Water fl.oz. 3 Ink for Writing or Etching en Metals. I. The most simple compound for writing on metals such as tin or zinc is a mixture of ordinary shellac-varnish with lampblack. The latter should be rubbed in a mortar with a little of the varnish until the mixture has become perfectly smooth and homogeneous, when it may be diluted with enough of the varnish to make it of the proper consistence. This mixture will produce dead black writing. If lustrous writing is desired, the shellac should be dis- solved in oil of turpentine. II. An ink for this purpose may also be made by making a solution of 72 grains copper sulfate in 3 fluidounces of distilled water, and adding 9 drops of hydrochloric acid. A little mucilage should also be added. And in order to be able to see the writing at once, a little pyrogallic acid may be added. For writing with this ink, a copper pen must be used. INK POWDERS OR EXTRACTS. Ink powders or extracts are dr}' prep- arations Intended for the extempora- neous manufacture of ink by treatment with water. Boiling distilled water must be used for solution as this prevents moulding of the ink. These powders are of similar composition to inks, and there are therefore aniline, logwood and nutgall ink powders and these mav make copying or non-copying inks of different colors. Aniline Ink Powders. In preparing ink from these powders, add to the material mentioned in the formula, 16 fluidounces of boiling dis- tilled water and stir with a wooden soatula until all is dissolved. Avoid metallic vessels in dissolving the pow- der. gr. gr. gr. 75 75 15 If the extracts are intended for coun- ter sale, the mixture should be wrap- ped in parchment paper. — D. I. For black writing ink : Phenol black B dr. 2]/ 2 Sugar dr. 2]/ 2 Potassium bisulfate gr. 8 Mix well by trituration. — D. II. For blue copying ink : Resorcin blue M Sugar Oxalic acid Mix well by trituration. — D. III. For blue writing ink : Resorcin blue M gr. 40 Sugar dr. 2 1 /6- Oxalic acid gr. 8 Mix well by trituration. — D. IV. For red copying ink : Eosin A, yellowish dr. 3 Sugar av.oz. y 2 Mix well by trituration. — D. V. For red writing ink: Eosin A, yellowish gr. no Sugar av.oz. V2 Mix well by trituration. — D. VI. For violet copying ink : Methyl violet 3 B dr. 2V2 Sugar gr. 75 Oxalic acid gr. 15 Mix well by trituration. — D. VII. For violet writing ink: Methyl violet 3 B gr. 75 Sugar gr. 75 Oxalic acid gr. 15 Mix well by trituration.— D. Logwood Ink Powders. In perparing ink from these powders, add 16 fluidounces of boiling distilled water to the mixture mentioned in the formula, stir for 10 minutes with a wooden spatula, allow to cool, set aside for 3 days in a cool place, and decant to clear liquid from the sediment. Avoid metallic vessels in dissolving these pow- ders. — D. VIII. For red copying ink. Logwood extract, best dr. 12 Potassium oxalate, neutral. . .dr. 5 Aluminum sulfate dr. 5 Potassium bisulfate dr. 2 l / 2 Salicylic acid gr. 24 Potassium bichromate gr. 12 Reduce to a coarse powder and mix them.— D. DOMESTIC UTILITIES. 1121 IX. For violet copying ink: Logwood extract, best dr. 12 Aluminum sulfate dr. 5 Potassium oxalate, neutral. av.oz. 1 Potassium bisulfate gr. 75 Potassium- bichromate gr. 40 Salicylic acid gr. 12 Reduce all to coarse powder and mix. — D. X. For writing ink: Logwood extract dr. & l / 2 Chrome alum dr. 6 Oxalic acid gr. 72 Potassium bichromate gr. 15 Salicylic acid gr. 10 Reduce all to coarse powder and mix. — D. Nutgall or Tannin Ink Powders. In preparing ink from these powders, add 20 fluidounces of boiling distilled water to the mixture mentioned in the formula, allow the mixture to boil for 25 or 30 minutes, then cool, transfer to a bottle, tie over the latter with paper, set aside in a cool place (in a cellar) for 3 or 4 weeks, and then decant the clear liquid from the sediment. If nec- essary, the several weeks storing may be dispensed with and the liquid used as soon as the solid matter has sub- sided. The main ingredients of these pow- ders is "oxidized tannin" which is pre- pared as follows : Oxidized Tannin. Tannic acid av.oz. 10 Potassium bisulfate av.oz. 3 Muriatic acid, commercial, .fl.oz. 1 Distilled water fl.oz. 15 Dissolve the tannic acid in the water in a flask by the- aid of a gentle heat, add the potassium bisulfate, first rubbed to a powder, and the acid, and heat on a water bath to a temperature of 80 to 90 C. for at least 10 hours, then re- move the contents of the flask by means of water, transfer it to a porcelain cap- sule, and evaporate on a water bath to dryness. The product weighs approximately 13 av. ounces. — D. XL For alizarin copying ink: "Oxidized tannin" av.oz. 1^4 Ferrous sulfate, exsiccated, .gr. 290 Sugar gr. 290 Indigotin gr. 40 Aniline green D gr. 25 Salicylic acid gr. 8 — D. XII. For alizarin non-copying ink: "Oxidized tannin" gr. 365 Ferric sulfate, dry gr. 290 Sugar dr. 2]/ 2 Indigotin gr. 30 Aniline green D gr. 20 Salicylic acid gr. 8 — D. XIII. For black copying ink: "Oxidized tannin" av.oz. i*4 Ferrous sulfate, exsiccated, .gr. 290 Sugar gr. 290 Phenol black B (coal tar dye) gr. 75 Salicylic acid gr. 8 — D. XIV. For black non-copying ink: "Oxidized tannin" gr. 365 Ferric sulfate, dry gr. 290 Sugar dr. 2 l / 2 Phenol black B (coal tar dye) dr. 1 Salicylic acid gr. 8 — D. XV. For blue copying ink: "Oxidized tannin" av.oz. 1*4 Ferrous sulfate, exsiccated, .gr. 290 Sugar dr. 5 Phenol blue 3 F (coal tar dye) gr. 24 Salicylic acid gr. 8 — D. XVI. For blue non-copying ink: "Oxidized tannin" gr. 365 Ferric sulfate, dry gr. 290 Sugar dr. 2 l / 2 Phenol blue 3 F (coal tar dve) gr. 24 Salicylic acid gr. 8 — D. XVII. For greenish-blue copying ink : "Oxidized tannin" av.oz. 1 1 4 Ferrous sulfate, exsiccated, .gr. 290 Sugar dr. 5 Phenol blue 3 F (coal tar dye) gr. 15 Aniline green D gr. 40 Salicvlic acid gr. 8 D. 1122 THE STANDARD FORMULARY XVIII. For greenish-blue non-copying ing: "Oxidized tannin" gr. 365 Ferric sulfate, dry gr. 290 Sugar dr. 2 l / 2 Phenol blue 3 F (coal tar dye) gr. 12 Aniline green D gr. 20 Salicylic acid gr. 8 — D. XIX. For green copying ink : "Oxidized tannin" av.oz. l% Ferrous sulfate, exsiccated, .gr. 290 Sugar dr. 5 Aniline green D gr. 40 Salicvlic acid gr. 8 — D. XX. For green non-copying ink : "Oxidized tannin" gr. 365 Ferric sulfate, dry gr. 290 Sugar dr. 2M2 Aniline green D gr. 40 Salicvlic acid gr. 8 — D. XXI. For red copying ink : "Oxidized tannin" av.oz. 154 Ferrous sulfate gr. 290 Sugar dr. 5 Ponceau R R (coal tar dye) dr. 1 Salicylic acid gr. 8 — D. XXII. For red non-copying ink: "Oxidized tannin" gr. 365 Ferric sulfate, dry gr. 290 Sugar dr. 2 l / 2 Ponceau R R (coal tar dye) gr. 40 Salicylic acid gr. 8 — D. XXIII. For violet copying ink : "Oxidized tannin" av.oz. iJ4 Ferrous sulfate, exsiccated, .gr. 290 Sugar dr. 5 Phenol blue 3 F gr. 16 Ponceau R R gr. 24 Salicylic acid gr. 8 "Phenol blue" and "ponceau" are coal-tar dyes. — D. XXIV. For violet copying ink : "Oxidized tannin" gr. 365 Ferric sulfate, dry gr. 290 Sugar gr. 145 Phenol blue 3 F gr. 12 Ponceau R R gr. 16 Salicylic acid gr. 8 "Phenol blue" and "ponceau" are coal-tar dyes. — D. XXV. Another and simpler formula is this: Xutgall, powder gr. 28c Ferrous sulfate, dried gr. 140 Copper sulfate, dried gr. 7 Gum arabic gr. 20 Boil this with a pint of soft or dis- tilled water for about 10 minutes. INK ERASIVES. Fresh ink spots are removed with compartive ease; old spots, especially after passing repeatedly through the laundry, are usually extinguished with considerable difficulty. The ink era- sives are intended for the removal of ink spots from paper as well as from fabrics. I. The following composition will re- move ink or writing fluids from paper, cloth, etc. : No. 1. Gtric acid av.oz. 2 Water fl.oz. 16 Saturated aqueous solution of borax fl.oz. 3 or 4 Dissolve the acid in the water and add the borax solution. No. 2. Chlorinated lime av.oz. 6 Water fl.oz. 16 Saturated aqueous solution of borax fl.oz. 3 or 4 Mix the lime and water, shake well, set aside for 1 week in a well stoppered bottle, decant the clear liquid, and add the borax solution. This composition is used by saturat- ing the ink spot with solution No. 1, removing excess of liquid with a blot- ter, and then applying solution No. 2. When the strain has disappeared, ap- ply the blotter, and wash the spot by the alternate use of clear water and blotting paper. Ink destroyed in such a manner can- not well be brought to view again by chemicals. II. Take of chlorinated lime 4 av. ounces, thoroughly pulverized, and 32 fluidounces distilled water. Shake well and set the mixture aside for 24 hours, in order to dissolve the lime, then strain DOMESTIC UTILITIES. 1123 through a cotton cloth, after which add 2 fluidounces of acetic acid to every pint of chlorinated lime water. This eraser is used by reversing the penholder in the hand, dipping the end of the reversed penholder into the fluid and applying it without rubbing, to the word, figure or blot required to be erased. When the ink has disappeared absorb the fluid with a blotter, and the paper is immediately ready to write upon again. This formula was patented in 1872. III. Treat the stain with stannous chlorid to reduce the ferric salt to the ferrous condition and then treat with oxalic acid solution. IV. A mixture of equal parts of ox- alic and tartaric acids has been recom- mended. When needed for use dissolve a small amount in water and apply to the spots. V. Stretch the goods over a hot dinner plate, moisten with hot water, then rub in with the bowl of a spoon a mixture of equal parts of potassium bitartrate and citric acid, rubbing until the spot disappears. VI. Dip the goods in hot water, rub the spots with crystals of oxalic acid; then soak in a 1:16 chlorinated lime solution, and, as soon as the stain dis- appears, rinse repeatedly in plenty of water. This requires great care. VII. Rub tallow over the ink spots, then wash in a solution of pyrophos- phate of sodium until both the tallow and ink have disappeared. The result depends on the reducing action of the pyrophosphate, which is perfectly harm- less. VIII. Moisten with hydrogen per- oxid solution. This acts similarly to stannous chlorid and iron pyrophos- phate. IX. As many black inks of the pres- ent day contain nigrosin, a method for its removal is included. Make a paste of chlorinated lime with cold water, 71 and rub a little of this over the ink spot with a wooden paddle. Next pour on a little vinegar or diluted acetic acid and continue to rub with the paddle. Lastly, rinse thoroughly with plenty of clear water. The operation may have to be repeated, provided the fabric and the Color can withstand such treatment. Ink Erasing Pencil. Pumice stone av.oz. 14 Sandarac av.oz. 2 Tragacanth av.oz. 1 Dextrin av.oz. 1 Mix all of the above in fine powder, add enough mucilage of acacia to form a pill mass, roll out into a pill pipe, and divide these into pencils 2 inches long. Dry and wrap in tin-foil. These are to be used like rubber era- sers. — D. INK STAINS, To Remove. For removing stains of writing ink, see Ink Erasives, for removing stains of indelible ink, see Silver Nitrate stains, To Remove. INSECT DESTROYERS. Insect destroyers are mentioned un- der the heading Ant Exterminators, Bedbug Exterminators, Buffalo Moths, Caternillar Lime, Flea Exterminators, Fly Exterminators, Gophers, Exterm- ination of, Insect Powders, Insects in Books, Insects in Drugs, Insecticides for Plants, Mosquito Exterminators, Moth Destroyers and Preventives, Phosphorus Pastes, Roach Extermin- ators, and Croton Bug Exterminators. The following preparations could not very well be classed elsewhere hence a separate heading is made for them. They may be used against a variety of insects. I. Resin av.oz. 1 Oil of amber, crude fl.oz. 1 Gasoline gall. 1 II. Sodium borosalicylate dr. 2 1 .- Decoction of quassia fl.oz. 10* This bitter solution, in Germany known as "liquor insecta fugans," is 1124 THE STANDARD FORMULARY claimed to be one of the very best ap- plications to ward off biting insects of any kind. — H. Hager's method of making sodium borosalicylate is as follows: Triturate together 20 parts of borax, 55 parts of salicylic acid and 9 parts of sodium bi- carbonate until the mixture is convert- ed into a pasty mass. Now incorpor- ate 150 parts of 70% alcohol and evap- orate on a water-bath, with constant stirring to dryness. If for the 70% alcohol specified, 100 parts of 90% al- cohol be used, the product will be whiter and the operation will proceed more rapidly. The product equals 60 parts. III. The following preparation is known as "tincture of insect flowers." Insect powder av.oz. 3 Alcohol sufficient Make 10 fluidounces of tincture. It may be applied as a preventive of insect stings; it may also be used, when mixed with an equal volume of alco- hol, as a spray for the destruction -of flies. — D. modified. An ethereal tincture may be prepared in a similar manner, using spirit of ether as a menstruum. It is to be used like the preceding. — D. Parasiticide Liquids. The parasiticide liquids may be pre- pared as follows. I. Liquor Naphthalini Benzinatus : Naphthalin av.oz. 3 Chloroform fl.oz. 4 Benzin fl.oz. 1 1 y 2 Mix at a temperature between 18 and 20 C, and shake until solution has been effected. II. Liquor Naphthalini Sulphocarbon- atus : Naphthalin av.oz. 6 Chloroform fl.oz. 10^2 Carbon disulfid fl.oz. 7 Prepare like No. I. For use in a more fluid form, either of these liquids is to be properly dilut- ed : the following being a good form- : la . Common family soap, dry. av.oz. Vz Castile soap, dry av.oz. y 2 Water fl.oz. 18 Alcohol fl.oz. 1 1 Liquor naphthalini benzin- atus fl.oz. 3 Dissolve the soaps in the water and alcohol, previously mixed, allow the li- quid to become cold, and then add the naphthalin solution. Before using the liquid, shake it thoroughly. If an ointment is required, S l A av. ounces of petrolatum and i J / 2 av. ounces of ceresin a.e melted together, and before the mass sets 18 fluidounces of the liquor naphthalini benzinatus are to be mixed with it. If either of these is to be used as a parasiticide upon animals, it should be applied with a stiff brush, in quantity only large enough to moisten the skin or to render the hair or fur slightly glossy. Under all circumstances it is preferable to avoid using these com- pounds at night time, as accidents may occur by approach to or contact with flames. IV. A patented insecticide (1885) is composed of carbolic acid, 2 ounces, quassia, i2 l / 2 pounds, Carolina tar, 5 pints, zinc sulfate, 10 ounces, and water, 25 gallons. This is directed to be sprayed upon carpet linings. INSECT POWDERS, Compounded. These are powdery mixtures which are used in place of ordinary insect powder. They may also be used instead of liquid insecticides. I. Insect powder . . .av.oz. U Quassia, fine powder... . . .av.oz. 6 II. Insect powder . . .av.oz. 14 Quassia, fine powder... . . . cv.oz. 4 Naphthalin . . .av.oz. 2 III. Insect powder . . . .av.oz 8 Borax, powder .... av.oz 8 Oil of cedar fl.oz 1 Oil of pennyroyal fl.dr 2 IV. Insect powder .... av.oz 8 Borax . . . .av.oz 8 DOMESTIC UTILITIES. 1125 Sulfur av.oz. 4' Oil eucalyptus fl.dr. 2 This is excellent for cockroaches. V. Paris green av.oz. 2 Plaster of Paris av.oz. 2 Borax, powder av.oz. 12 German chamomile av.oz. 1 Powder the chamomile flowers and mix with the other powders. This is said to be used by profes- sional bug exterminators. VI. Tobacco dust (or Scotch snuff) av.oz. 12 Sulfur av.oz. 8 Insect powder av.oz. 8 Naphthalin av.oz. 2 Oil of cedar fl.oz. 1 Chalk, to make av.lb. 4 VII. Another insecticide is described as having this composition : Insect powder parts 33 Borax parts 48 Glucose, sugar, or other sac- charine substances parts 12 Flour (preferably rice flour) parts 7 It is very alluring to all forms of in- sect life and has the advantage of be- ing entirely non-poisonous to human be- ings and domestic animals. INSECTS IN BOOKS, To Prevent. The following has been recommend- ed: Mix 3 parts of camphor and 1 of carbolic acid, dissolve by gentle heat and add an equal volume of sweet oil. Moisten a cloth with the liquid and go lightly over the covers and edges of the book. INSECTS IN DRUGS. According to the U. S. Department of Agriculture, the principal insect found in drug stores is what is called the "drug-store beetle" (Sitodrepa panicea Linne). According to the Department pamphlet "in pharmacies this insect runs nearlv the gamut of everything kept in store, from insipid gluten wafers to such acrid substances as wormword, from the aromatic cardamom and anise to the deadly aconite and belladonna. It is particularly abundant in roots, such as orris and flag and sometimes infests cantharides." But not alone does it attack drugs but it invades mills, granaries, tobacco warehouses, etc. It enters the household and is often found in flour, meal, breakfast foods, and condiments. It is partial to red pepper and occurs in ginger, rhubarb, chamomile, boneset, and other roots and herbs that were kept in the farmhouse in olden days. It sometimes gets into dried beans and peas, choco- late, black pepper, powdered coffee, lic- orice, peppermint, almonds, and seeds of every description. It must be remembered that it is not the beetle itself that does the harm but it is the larva or grub hatched out from the egg laid by the mature beetle that bores into all manner of roots, herbs, meals, etc., and ruins them for all purposes. Through an extended series of invest- igations made at trie University of Kansas, it was ascertained that a num- ber of other insects infest drugs, vari- ous ticks, mites, etc., for example. An excellent manner of destroying all insects in drugs is bv means of chloro- form. A small amount is to be poured into the container containing the in- fested drugs. The chloroform, if used prior to infestation, will also prevent the attacks of insects. It is therefore a wise policy to acd a few drops of chloroform to the container for rhu- barb, cantharides, and other drugs which are so frequently worm-eaten. The chloroform does no harm to the drugs as upon a few moments expo- sure to the air, it is entirely dissipated. Chloroform poured on pressed herbs in packages and similar articles will destroy all the worms. INSECTICIDES FOR PLANTS. Under this heading are mentioned various remedies used by farmers, gar- deners, florists, and others against dif- ferent kinds of worms, bugs, and vari- ous insects and fungi which attack and destroy plants and trees. 1126 THE STANDARD FORMULARY The formulas, directions, hints, etc., here given are taken from the reports of the U. S. Department of Agricul- ture and of various State agricultural experiment stations, and are to be con- sidered as entirely trustworthy. For remedies to combat the fungous diseases of trees, see under heading Fungicides. Kerosene as an Insecticide. Kerosene is an excellent insecticide, destroying all kinds of insects feeding on plants but in an undiluted form it is too caustic, destroying the delicate plant parts. Various mixtures con- taining kerosene in an emulsified form have been used with success, among them the following: Riley Hubbard Kerosene Emulsion: This insecticide acts by contact, and is applicable to all non-masticating in- sects (sucking insects, such as the true bugs, and especially plant lice and scale insects), and also to many of the man- dibulate insects when the use of arsen- ites is not advisable. Kerosene emul- sion may be made by means of various emulsifying agents, but the most sat- isfactory substances, and those most available to the average farmer and fruit-grower, are milk and soapsuds. In each of these cases the amount of emulsifying agent should be one-half the quantity of kerosene. One of the most satisfactory for- mulas is as follows : Kerosene gall. 2 Common soap or whale-oil soap av.oz. 8 Water gall. 1 Dssolve the soap in the water by the aid of heat, and add the solution boil- ing hot to the kerosone. Churn the mixture by means of a force pump and spray nozzle for 5 to 10 minutes. The emulsion, if perfect, forms a cream which thickens upon cooling, and should adhere without oiliness to the surface of glass. Nof free oil should rise from surface of the liquid, as this would inure the foilage. For use against scale insects, dilute one part of the emulsion with 9 parts of water. For most other insects, dilute one part of the emulsion with 15 parts of water. For soft insects, like plant lice, the dilution may be carried to from 20 to 25 parts of water. For most in- sects the proper dilution is with 15 parts of water. This liquid should be applied by force, and enough used to thoroughly wet the insects. Kerosene Emulsion (milk formula): Kerosene gall. 2 Sour milk gall. 1 Heating is unnecessary, the two be- ing churned together. The change is from a watery liquid to a thick, but- tery consistency, which takes place very suddenly after 3 to 5 minutes agitation. With sweet milk, difficultv will be ex- perienced, and if the emulsion does not result in 5 minutes, the addition of a small amount of vinegar will produce the result promptly. It if better to prepare the milk emul- sion from time to time for immed iate use, unless it can be stored in air-tight jars; otherwise it will ferment and spoil within a week or two. Instead of kerosene, crude petroleum oil may be used, Beaumont oil being the kind used by the Department. The emulsion is directed to be prepared in this wise : Crude petroleum gall. 2 Water pints 4 Hard soap av.oz. 8 Dissolve the soap in the water (soft) with the aid of heat; to this add the petroleum, mix with a spray pump or shake vigorously, and dilute with the desired amount of water. Soap con- taining an amount of free alkali equiv- alent to 9/10% of sodium hydroxid gives the best emulsion. All of the laundry soaps examined by the De- partment were quite satisfactory but toilet soaps were usually not suitable. " Arsenical Insecticides. These poisons (Paris green or Lon- don purple) are of the greatest serv- DOMESTIC UTILITIES. 1127 ice against all mandibulate insects, as larvae and beetles, and they furnish the most satisfactory means of controlling- most leaf-feeders, and the best whole- sale remedy against the codling moth. Caution must be used in applying them on account of the liability of burning- or scalding the foliage. The poisons should be thoroughly mixed with water at the rate of from I pound to 100-250 gallons of water, and applied with a force-pump or hand spray-nozzle. In preparing the wash it will be best to first mix the poison with a small quantity of water, making a thick batter, and then dilute the latter and add to the reservoir or spray-tank, mixing the whole thoroughly. When freshly mixed, either London purple or Paris green may be applied to apple, plum and other fruit trees (except the peach) at the rate of 1 pound to 150- 200 gallons, the latter amount being recommended for the plum, which is somewhat more susceptible to scalding than the apple. White arsenic does little if any injury at the rate of 1 pound to 50 gallons of water. It has been shown, however, that when al- lowed to remain for some time (two weeks or more) in water the white ar- senic acts with wonderful energy, scalding when used at the rate of 1 pound to 100 gallons from 10 to 90% of the foliage. The action of the other arsenites remains practically the same, with perhaps a slight increase in the case of London purple. With the apple, in spraying for the codling moth, at least two applications should be made — the first on the fall- ing of the blossoms, the apples being about the size of peas, and the second a week or 10 days later — but the poison should never be applied after the fruit turns down on the stem, on account of the danger of the poison collecting and remaining permanently in the stem cavity. For the plum curculio on the plum, cherry, peach, etc., two or three appli- cations should be made during the lat- ter part of May and the first half of June. In the case of most leaf-feeders, spray on the first indication of their presence. The following formula may also be employed : Paris green or London purple av.oz. 3 to 4 Fresh lime." , av.oz. 8 Flour av.oz. 16 Water gall. 45 Shake the lime in a gallon of water and rub till smooth; then strain and stir in the arsenite. Boil the flour to a thin paste. Dilute the arsenite with the necessary water, then add the flour paste and use. This is the standard remedy for all kinds of leaf-gnawing insects. A good sample of London pur- ple is just as effective as Paris green, and usually costs less. The lime is add- ed to neutralize any soluble arsenite compounds, and the flour is used to make the arsenite adhere better to the foliage. With the peach, these poisons, when applied alone, even at the rate of 1 pound to 300 or more gallons of water, are injurious in their action, causing the loss of much of the foliage. By the addition of a little lime to the mixture, London purple and Paris green may be safely applied at the rate of 1 pound to 125 to 150 gallons of water to the peach of the tenderest foliage, or in much greater strength to strong foliage, such as that of the aople cr most shade trees. Whenever, therefore, the application is made to tender foliage, or when the treating with a strong mixture is de- sirable, lime water, (milky, but not heavy enough to close the nozzle) should be added at the rate of about 2 gallons to 100 gallons of the poison. Pure arsenic, however, should never be used with lime, as the latter in- creases its action. 1128 THE STANDARD FORMULARY Other arsenicals that may be used are arsenite of lime, arsenate of lead, and copper arsenite. The latter may be used in place of Paris green as it is the pure arsenite whereas Paris green is an indefinite mixture of acetate and arsenite of copper. Arsenite of lime may be prepared ac- cording to Kedzie's formula : White arsenic av.lb. I Sal soda, crystal av.lb. 4 Water gall. 1 Boil the arsen. and soda in the water for 20 minutes or until dissolved. Add enoueh water to make up for the loss by evaporation. This stock mixture will keep indefinitely. For ordinary spray- ing operations, add 1 pint of this mix- ture to 40 p-allons of water in which has been previously mixed about 3 pounds of freshly slaked lime. The soda is used to hasten the process and to insure the combination of all the arsenic with the lime. Arsenate of lead is prepared by com- bining approximately 3 parts of crys- tallized sodium arsenate with 7 parts of crystallized lead acetate in water. It may be used in strength of 3 to 15 pounds (meaning the combined weights of the two chemicals) to 100 gallons of water without injury to the foliage and in this respect is much safer on delicate plants than any other arsenical. White Hellebore as an Insecticide. Powdered white hellebore (Veratrum album) is often recommended and used as an insecticide, particularly as a sub- stitute for arsenicals. This substance is useful when a few olants only are to be sprayed, as in yards or small gar- dens but it is too expensive for large operations. It kills insects in the same way as the arsenicals, as an internal poison, and is less dangerous to man and the higher animals, but if sufficient be taken it will cause death. It is particularly effective against the larvse of sawflies, such as the cherry slug, rose slug, currant worms, and straw- berry worms. It may be applied as a dry powder, preferably diluted with from 5 to 10 parts of flour and dusted on the plants through a muslin cloth or with a powder bellows. The application should be made in the morning when the plants are moist with dew. Used as a wet application, it should be mixed with water in the proportion of one ounce to the gallon of water and ap- plied as a spray. INTENSIFYING SOLUTIONS for Photography. I. Lumiere's iodid intensifier : Mercuric iodid gr. 90 Sodium sulfite, dried av.oz. 2 Distilled water, to make. . . .fl.oz. 10 Mix and dissolve. This can be dissolved immediately after the negative has been fixed and rinsed. II. Monckhoven's intensifier : Murcuric chlorid gr. 90 Potassium bromid gr. 90 Distilled water fl.oz. 10 In this immerse the negative till bleached, wash well, and immerse till blackened, in the following: Silver nitrate gr. 00 Potassium cyanid gr. 180 Distilled water fl.oz. 10 Dissolve the two salts separately in half the water, then add the cyanid solution slowly to the silver solution, shaking thoroughly after each addi- tion until the white precipitate first formed is nearly, but not quite, dis- solved. III. Bromid of copper intensifier : Copper sulfate gr. 249 Potassium bromid gr. 236 Distilled water fl.oz. 10 Dissolve each salt separately in half the water, mix the two solutions, and filter. The negative must be free from hypo and then immersed, in daylight, in the solution, and after well washing should be redeveloped with any developer such as metol or hydroquinone, but not with pure pyro and ammonia. If very great intensification is required, only rinse the negative and flow over it a 10% DOMESTIC UTILITIES. 1129 solution of silver nitrate, and wash thoroughly. IODOFORM, Removing Odor of. Various methods of removing the odor of iodoform from hands, mortars, etc., are recommended. To remove from a mortar wash the latter with soap and water, dry it, and then burn some alcohol in it. Another method recommended is to rub out the vessel with sawdust, wash it with hot water and soap, then rub out with linseed meal, and finall" re- move the linseed with water. Still another method recommended for removing the odor from the hands utensils, etc., is to rub with a small ouantit- of tannic acid, then wash in the usual manner. IVORY, Bleaching of. A prominent manufacturing firm rec- ommends the following two methods for bleaching ivory : I. Wash the ivory with a 3% solu- tion of sodium perborate, then wipe off with lemon juice or solution of citric acid. II. Wash the ivory alternately with a 2% solution of sodium perborate and a 1% solution of oxalic acid, allowing the ivory to remain in each solution about half an hour> Repeat the process a number of times, then rinse with water and wipe dry. It may be necessary, after bleaching the ivory, to repolish it. This may be done by applying any white polishing paste with a woolen cloth, washiner with castile soap, drying, and then rubbing with a chamois skin. IVORY, To Color. See Horn and Ivory, to Color Black, also the following: I. Black: Boil first in a decoction of logwood and immerse for a short time in a solu- tion of iron sulfate. Or wash in an al- kaline solution such as ammonia water, then steep in a neutral solution of silver nitrate, and expose to the light. II. Blue: Steep in a solution of soluble blue. III. Green : Steep in a solution of verdigris in di- luted acetic acid. IV. Purple: Boil the ivory in a decoction of log- wood, then for every pint of decoction add Y-2 av. ounce of alum, and boil in this mixture. V. Red: Dip the ivory in a weak solution of nitric acid and then place in solution of carmine or cochineal coloring N. F. Or, boil the ivory with 3 av. ounces of Brazil wood and 2 pints of water, then add 1 av. ounce of alum, and boil once more. VI. Yellow: Steep for some hours in a solution of led acetate, then dry, and put into a solution of potassium bichromate. Or boil for one hour in a solution made of 2 av. ounces of alum in 1 pint of water, then steep in a decoction of 4 av. ounces of turmeric in 1 pint of water; lastly mix the two solutions and boil therein for one hour. JAPANS. The following are given as good formulas for the preparations known by this name : I. Asphaltum av.oz. 8 Balsam of copaiba av.oz. 8 Oil of turpentine sufficient Melt the asphaltum over a direct fire, add the balsam, previously warmed, al- low to cool somewhat, and then incor- porate enough of turpentine to bring the mixture to the proper consistency. II. Rub lampblack to a very fine con- dition with a little oil of turoentine, then add enough copal varnish. III. Asphaltum av.oz. ^4 Burnt umber av.oz. 2 Boiled linseed oil fl.oz. v ;j Oil of turpentine sufficient Melt the asphaltum, stir in the lin- 1130 THE STANDARD FORMULARY seed oil, previously heated, then add the umber, and, when cooling, thin with oil of turpentine. JAVELLE WATER. This may be prepared as follows : Sodium bicarbonate av.oz. 32 Chlorinated lime av.oz. 8 Water fl.oz. 64 Boil the sodium salt in the water for a few minutes, add the chlorinated lime, allow to cool, and then strain. JEWELER'S ROUGE. (Colcothar— Crocus Martis.) This is usually prepared by heating ferrous sulfate to a high temperature, but a simpler method is this : Make a tolerably strong solution of ferrous sulfate, also one of oxalic acid, filter each; add the former to the lat- ter, with constant stirring, let stand a few hours, collect the precipitate, wash it thoroughly with water, dry, and ex- pose to the direct flame until there is no further change of color. KEROSENE, To Mask Odor of. The odor of kerosene may be re- moved by purifying in the same as ben- zin is purified in the U. S. P. process. To disguise or mask various strong- smelling substances are recommended but the best is said to be 1% of amyl acetate. This is said to make an aro- matic liquid which burns with a bright, clear light. KNIFE HANDLES, To Fasten. When the handle of a case knife, spatula or other article of this kind gets loose, it may be made tight again by the following process : Melt together 12 parts of rosin and 3 of sulfur and stir in 5 parts of iron filings; pour the mixture while hot into the cavity, insert the tang, and let cool slowly. The tang should be heated slightly as it insures a firmer joint with the molten mass. The following cement is also recom- mended : Rosin parts 4 Yellow wax part 1 Plaster of Paris .part 1 Melt rosin and wax, incorporate the plaster, and use this cement while hot LABEL VARNISH. See under the heading Varnishes. LACQUERS. These are solutions of resinous sub- stances, generally in alcohol, but wood or denatured alcohol may be used in- stead. They are used generally as pro- tective coatings for metals to prevent the oxidizing effects of the atmosphere. They may be colored or tinted, the col- oring substances being usually also res- inous substances such as dragon's blood. See also the Varnishes which are sim- ilar preparations. Lacquers for Brass. Before applying any lacquer to brass, it must be well cleaned. This may be done by immersing in a bath of strong solution of caustic potash or lye, followed, after rinsing, by a bath .of dilute nitric acid. Then rinse with water, rub dry, and then place on a hot iron plate or on top of the stove, until warm. Then apply the lacquer with a soft brush (camel's hair or sable), making all the strokes in one direction. Some practice is necessary in order to obtain a nice, even coating. Dark Lacquer for Brass. I. Turmeric, powder av.oz. 2 Annatto av.oz. V2 Saffron, Spanish av.oz. l /. Shellac av.oz. 6 Alcohol fl.oz. 30 Macerate all together for several days, agitating frequently, then strain or filter. Wood or denatured alcohol may be substituted for the alcohol. II. Shellac av.oz. 3 Turmeric, powder av.oz. 1V2 Aloes, powder dr. 4 Mastic dr. 2 Dragon's blood, powder dr 2 Venice turpentine dr. 1 Alcohol fl.oz. 30 Mix, macerate for several days, agi- tating frequently, and strain or filter. DOMESTIC UTILITIES. 1131 III. Seed lac av.oz. 3 Turmeric, powder av.oz. 1 Dragon's blood dr. 2 Alcohol fl.oz. 16 Mix, macerate for several days, agi- tating frequently and filter. Gold Lacquer. IV. Shellac av.oz. 2 Dragon's blood, powder dr. 4 Turmeric, powder dr. 1 Wood alcohol fl.oz. 32 Mix, macerate for several days, nref- erably in a warm place, agitate fre- quently, and strain or filter. This is said to be used in Germany. It is said to be useful to impart a gold tint to tin and other white metals. V. Mastic av.oz. Vz Sandarac av.oz. 24 Venice turpentine av.oz. V/ 2 Shellac av.oz. 3 Alcohol fl.oz. 30 Fuchsin av.oz. 1 Aniline violet av.oz. V 2 VI. Seed lac av.oz. 2 Amber gr. 90 Gambage gr. 45 Saffron, Spanish gr. 10 Red saunders, powder dr. 2^ Dragon's blood, best av.oz. y 2 Glass av.oz. 1 Alcohol fl.oz. 17 Reduce all the resins to coarse pow- der by beating in a mortar with the glass, then add the other ingredients, macerate for a number of days, and finally allow the solids to subside, de- cant the clear liquid, and strain or fil- ter the latter.— H. Red Lacquer for Brass. VII. Sandarac av.oz. 4 Annatto av.oz. 2^ Dragon's blood, powder. . .av.oz. 1 Oil of turpentine fl.oz. 2 Alcohol fl.oz. 16 Mix, macerate for several days, agi- tating frequently, then strain or filter. VIII. Seed lac av.oz. 5 Sandarac av.oz. 2 Mastic av.oz. 2 Venice turpentine av.oz. 1% Red saunders av.oz. 24 Gambage av.oz. y 2 Dragon's blood, powder. . .av.oz. V2 Annatto av.oz. y 2 Alcohol fl.oz. 30 Mix, macerate for several days, agi- tating frequently, and strain or filter. Wood or denatured alcohol may be sub- stituted for the alcohol. Lacquer for Leather. See Harness Varnish or Lacquer. Protective Lacquer. This may be applied to any polished metal to protect it against the atmos- phere : IX. Shellac av.oz. 1 Sandarac av.oz. 1 Venice turpentine ..dr. 1 Alcohol fl.oz. 1454 Mix, macerate for several days, agi- tating frequently, and filter or strain. Lacquer for Tin. X. Red saunders gr. 40 Saffron gr. 80 Dragon's blood, powder dr. 3 Sandarac av.oz. Vz Mastic av.oz. j£ Balsam of fir av.oz. y 2 Turmeric, powder av.oz. 1 Shellac av.oz. 2 Alcohol fl.oz. 16 Mix, macerate for several days, agi- tating frequently, and strain or filter. Wood or denatured alcohol may be substituted for the alcohol. See also Nos. IV. and IX. LAUNDRY BLUING. See Bluing, Liquid, and Bluing Ball. LAUNDRY GLOSS. See Starch or Laundry Gloss. LAWN FERTILIZER. See Fertilizers. LEATHER BLACKING AND POLISH. See Harness Blacking and Polish ; Shoe Blacking, Liquid; and Shoo Blacking, Paste Form. LEATHER-CLEANING PASTE. This is accredited to the Marquis of Lothian's groom : 1132 THE STANDARD FORMULARY Pipe clay Spanish white . . Flake white Precipitate chalk. Spermaceti Lard .av.oz. 8 .av.oz. 4 .av.oz. 3 .av.oz. 2 .-av.oz. J/2 .av.oz. 4 This is said to be useful for cleaning white leather, kid, etc. LEATHER DRESSING AND OIL. See under Shoe Dressing, Shoe Grease, and Harness Dressing and Oil. LEATHER DYEING. ^ee Dyeing of Leather. LEATHER POLISH. These are especially intended for chair leather : Eggs, white and yolk No. 5 Sperm oil fl.oz. 6 Acetic acid fl.dr. 6 Glycerin fl.dr. 6 Oil of turpentine fl.oz. i Alcohol fl.oz. 5 Water, to make fl.oz. 32 Beat up the eggs thoroughly with an egg-beater, mix the oils, acid, and gly- cerin, and add gradually to the eggs, using the beater constantly. Transfer to a bottle, and add the alcohol diluted with its own volume of water, adding this gradually, shaking frequently mean- while. Finally add the remainder of the water. A dram of birch-tar may be added to this to give it a Russia-leather odor. The directions for use are to pour about a teaspoonful of the polish upon the chair-leather, and rub it gently over with a soft cotton rag until it is dry. A few minutes later polish gently with a clean rag. Leather backs of chairs should be reserved until the seats are polished ; then use the wet rag, sprinkling a little of the polish upon it, and finish off with the dry rag. This polish keeps the leather soft and preserves it. It should be used about once a week. It is advisable not to color it, because leathers differ so great- ly in color. For green leather the frayed parts should be touched up with, green ink before using the polish: for brown leathers a solution of Bismarck brown or liquid annatto may be used; and for crimson leathers red ink is best. The dye-tones are subdued by the pol- ish. LEATHER VARNISH or Lacquer. See Harness Varnish. LEECHES, Keeping of. As soon as the leeches arrive from the dealer, they should be at once re- moved from the box and washed thor- oughly in soft water which should be above 15 C. The first washing re- jected, they should then be placed in a jar half-filled with water at about the same temperature, with a piece of clean muslin tied over the mouth of the jar and covered with a perforated lid. Care must be taken that the water replaced be no colder than the water thrown away. The jar should be well cleansed once or twice a week in winter and about every other day in summer, this preventing the accumulation of any for- eign matter along the sides of the jar, and the leeches taken out and gently rubbed between the fingers or between the folds of a soft cloth to free their bodies of the mucous or slum sub- stance which envelopes them. Guard also against the access of acrid vapors which may come in contact with the jar, such as ammonia gas and the va- por of mineral acids which by their density find a ready means of access through the perforated lid to become absorbed by the water in the jar. A good authority gives the following information: Leeches secrete a large amount of mucous which absolutely re- quires to be removed and it is for this purpose that gravel should be placed in the leech jar. This mucous decom- poses, giving rise to ammonia and other noxious products so that the water must be changed frequently. The sides of the jar must be kept free from slime by scouring. As a rule, a diseased leech will infect its companions so that as soon as it is observed it should be re- DOMESTIC UTILITIES. 1133 moved to a jar by itself and the orig- inal jar cleansed and disinfected by- rinsing with potassium permanganate solution. Leeches must be kept at an even tem- perature ranging between 10 and 20 C. ; fresh water when added should be of the same temperature ; air should have free access ; but light should be ex- cluded. Vapors of ammonia, acids and benzin are injurious to leeches. LETTERS TO GLASS, To Fasten. See Enameled Letters, To Fasten. LIBRARY PASTE. See Paste, Library. LIGHTS, TABLEAU OR BENGAL. See Fires, Colored. LINOLEUM, Cleaning and Polishing. To give a clean, bright appearance to a linoleum floor, wash it well with warm soapsuds and rinse with clear, warm water until perfectly clean. As soon as the surface is dry apply a coat- ing of equal parts of raw linseed oil and turpentine, using a wide paint brush for the application. It will be found best to apply the mixture of oil and turpentine at night, so as to allow the oil to penetrate to some extent. In the morning any surplus oil may be wiped off with old rags. The linoleum should be treated in this way about once a month. The floor should be swept with a soft floor brush, which is preferable to a broom, which is apt to scratch the surface of the linoleum and is, besides, less efficient for removing fine dust. The linoleum should be washed at least once a day with a lar°-e sponge clamped on a mop stick. Thus treated a lino- leum floor surface will always look well and wear more durably. The following is recommended as a polish for linoleum : Yellow wax av.oz. I Carnauba wax av.oz. 2 Oil of turpentine fl.oz. 10 Benzin fl.oz. 10 Melt the two waxes, carefully add the oil and benzin, and stir until solid. — D. This is used as a varnish for lino- leum, oil carpet, etc. : Yellow wax part 1 Amber varnish part 1 Oil of turpentine parts 2 Melt the wax, add the oil and then the varnish. This is to be applied by means of a woolen cloth. — D. LINSEED, To Keep Free from Bugs. To keep flaxseed free from bugs it has been advised to use as a container of a tin can (which may be obtained of anv size up to about 100 lb. capacity) with a closely-fitting cover, and at the bottom of the can placing a small vial of chloroform with a loosely-fitting cover. Then pour in the linseed, whole or ground, into the can, covering the vial. Enough of the chloroform will escape from the bottle to kill what- ever insects infest the flaxseed. LUBRICANTS. See Axle Greases. LUMINOUS PAINT. See Paint, Luminous. MAGNESIUM LIGHTS. See under Colored Fires for such of the fires as contain metallic magne- sium. MANIFOLD PAPER. See Paper, Carbon or Manifold. MARBLE BUSTS, To Clean. First free from all dust and then wash with very weak hydrochloric acid ; do not use soap. MATHEMATICS. To calculate the area of a circle, square the diameter, and multiply by 0.7854 (or n-14) ; or multiply the diam- eter by the circumference, and divide by 4. To estimate the capacity of a can or any vessel with straight sides (of the same diameter throughout), multiply the diameter by 0.7S54, and this result by the height or depth of the can. Where the vessel is larger at one end than at the other, and the sides are straight, add the ends together and 1134 THE STANDARD FORMULARY divide by 2 to get the mean diameter, and proceed as before. To measure the cubic contents of a barrel or keg with curved staves, add the diameter at the bung and that of the head (both measured from the inner rim of the staves) together; divide by 2 to get the mean diameter; multiply as before by 0.7854, and finally multi- ply by the length of the stave, taken from the inside of the heads. This lat- ter process is not absolutely mathe- matically correct, but is so close as to answer for all practical purposes. MERCURY STAINS FROM SIL- VER, To Remove. See Silver, To Remove Mercurial Stains from. METAL COLORING. See under the following headings : Bluing of Gun Barrels; Bronzing of Gun Barrels ; Browning of Gun Barrels ; Copper, Bluing of; Copper, Browning of; Silver, "Oxidizing" of; and Zinc, Coloring. METAL POLISHES. See Putz Pomades; Putz Tablets; Brass, Polishes for; Polishing Pow- ders; Polishing Cloths; Silverware Pol- ishes; also the following: I. Tripoli av.oz. 8 Soft soap av.oz. 4 Water, to make fl.oz. 32 Rub up the tripoli with a portion of the water to a smooth paste, dissolve the soap in another portion of water, add with trituration to the tripoli paste, perfume with oil of mirbane, and add sufficient water to make one quart. An ounce or two of oxalic acid would be a good addition. If the mixture is too thick add more water. II. Rosin av.oz. 1 Whiting av.oz. 4 Tripoli av.oz. 4 Gasoline fl.oz. 32 Dissolve the rosin in the gasoline and add the other ingredients. In using avoid proximity to lights and fires. III. Rotten stone av.oz. % Jeweler's rouge (crocus martis) av.oz. i 1 /? Liquid petrolatum fl.oz. 20 Mix well. IV. . .av.oz. 2 . . av.oz. 4 . .av.oz. 6 Paraffin wax Oleic acid, crude Liquid petrolatum . Kieselguhr or precipitated silica av.oz. 8 Melt the paraffin, add the acid and liquid petrolatum, and then incorporate the oowder. V. Tripoli av.oz. 6 Pumice stone, powder av.oz. 1 Tartaric acid dr. 2 Gasoline fl.oz. 28 METALLIC TREES. See under Chemical Garden. MICA IN STOVES, Cleaning of. The mica in stove doors can readily be kept bright by rubbing with a sponge saturated with benzine, and then wio- ing well with a towel. Of course there should be no fire in the stove. MICE EXTERMINATORS. The same articles may be used for exterminating mice that are used for de- stroying rats. See Rat Exterminators. MILDEW SPOTS, To Remove. Mildew spots on white goods may in most cases be removed by a bleach- ing process. This may be done in a variety of ways, depending, to some ex- tent, upon the nature and texture of the fabric. The latter should be thoroughly washed, and, while still damp, may be immersed, or touched over, with dilute Javelle water or solution of chlorinated soda or with hydrogen peroxid solu- tion. Dilute bromin water may also be used. Sometimes a treatment similar to that used for removing ink stains is successful, treating the stains with a very concentrated solution of oxalic or citric acids, or both. In most cases it is of advantage to expose the fabric in a damp state, to the rays of the sun. DOMESTIC UTILITIES. 1135 MIRRORS, Frosting of. Mirrors may be given a frosted effect by applying a coating of a solution of Epsom salt. Water may be used as a solvent but stale beer or ale possess adhesive properties which make it bet- ter for this purpose. The liquid is to be applied with a small, clean sponge, and allowed to dry. The liquid may be tint- ed if desired with whiting, carmine, Prussian blue, or other suitable sub- stance. MODELLING WAX, DENTAL. See Dentists' Molding Wax. MOLDS for Taking Impressions. I. Spermaceti, stearin, or tal- low av.oz. 8 White wax av.oz. 8 For taking impression of medals, etc. II. Resin av.oz. 12 Beef tallow av.oz. 8 For coarse work, such as architec- tural ornaments. III. Flexible or elastic molds may be made of gutta percha softened in boil- ing water, and after being freed from moisture, pressed strongly against the objects to be copied. The same can be produced by the use of gelatin or glue, which has been dis- solved in sufficient hot water and pass- ed over the object previously oiled. MOLD IN CELLARS, To Prevent. For this purpose the cellar walls should be often coated with whitewash. The surfaces of the casks may be paint- ed with borax solution; for cask fauc- ets, buckets and funnels, impregnation Outside with hot paraffin and washing inside with formaldehyde solution are useful. The latter may also be used in place of sulfuring. For cask stands, cellar steps and doors, employ impreg- nation with copperas or bluestone solu- tion. Formaldehyde in the proportion of 1 part of formaldehyde to 40 parts of water is an excellent washing and cleansing medium. MOSQUITO EXTERMINATORS. Mosquitoes are bred in pools of stag- nant water, consequently the best means of preventing their propagation is by- keeping pools, marshes and other low places well drained. In case this is not possible the next best plan is to throw kerosene on the stagnant pools, which should be done about every 2 weeks. Another substance which destroys mos- quito larvae is potassium permanganate. The Daily Telegraph of London in- vited its readers, a few years ago, to send in the names of substances which in their experience had proven service- able as mosquito repellants. The fol- lowing were among the substances rec- ommended : Eucalyptol on the skin, with a hand- kerchief saturated with it placed on the pillow at night — the result of South Af- rican experience. Carbolated vaseline. One drop of oil of lavender on the pillow and one on the head at night. Tincture of Ledum palustre. Piece of absorbent cotton soaked in oil of clove on each side of the bed curtains. Anoint the skin with a mixture of 1 part of camphor and 3 of paraffin. Oil of eucalyptus. Oil of eucalyptus and creosote, each 5 drops, mixed with an ounce of glyc- erin. Mosquito Pastilles. To drive mosquitoes from a room, various articles, such as camphor gum or insect powder, are sometimes burned. Good, salable articles for this purpose may be made in the form of pastilles, such as the following: I. Carbolic acid fl.oz. 1 Potassium nitrate, powder, .av.oz. 1^2 Insect powder av.oz. 3 Charcoal, powder av.oz. 6 Make a paste with powdered traga- canth and water and mold into pas- tilles weighing about 2 drams each. 1136 THE STANDARD FORMULARY II. Thyme leaves av.oz. 2 Lavender flowers av.oz. 2 Insect powder av.oz. 2 Potassium nitrate, powder. av.oz. 2 Potassium chlorate, powder... dr. 1 Tragacanth, powder dr. 3 Reduce the thyme and lavender to coarse powder, add the other ingredi- ents, mix with sufficient water to form a mass, divide into pastilles, and dry. MOTH DESTROYERS AND PRE- VENTIVES. Camphor and naphthalin, the latter usually in the form of "moth balls," have been relied upon mostly as preven- tives against the ravages of moths. As is probably known to nearly everyone, it is not the moth itself that does the harm but its larva, which feeds on and burrows in clothing, especially such as is composed of animal tissue, wool, feathers, fur, etc. Whether or not these substances actually have any deterrent effect upon the moth or its larva is very problematical. Camphor cannot be used abundantly enough on account of its present high price, while naphthalin, though cheap enough, is objectionable to many persons on account of its odor, which clings too persistently to clothing that has been preserved with it. Nu- merous other expedients have been adopted to avoid, or at least mitigate, the ravages of moths. Wrapping the goods in tarred paper or paper treated with naphthalin has been tried. Cotton cloth, not being attacked by these in- sects, has been suggested for wrapping up the more expensive woolen and fur clothing while the latter is not in use during the summer months. Cedarwood chests are also used for storing away clothing to prevent the attack of moths. The most approved method of storing clothing to save them from moths is cold storage. This method is entirely successful, as moths do not breed or hatch at a temperature below 40 F. In case none of these methods can be followed, the clothing, upholstered fur- niture and other articles attacked by moths or liable to attack should, at frequent intervals, be taken out and ex- posed to the light, strong sunlight if possible, and be well beaten with a stick. Both light and beating are inim- ical to the insects, the beating dislodg- ing the larva from their nests. To com- plete the work of destruction, the in- fested articles should be thoroughly drenched with gasoline or benzine, which absolutely destroys all the re- maining larva. Moths in sofas and other forms of furniture may be exterminated by in- jecting full-strength formaldehyde into the crevices. It is said the entire col- ony may be exterminated in a few weeks. The furniture may be used 24 hours after treatment. This should be done in the open air, owing to the high- ly irritant nature of the formaldehyde. These moths, known also as the clothes moths, should not be confused with what are known as buffalo moths or carpet beetles, which are described under the heading Buffalo Moths. Other preparations which are used as moth preventives and destroyers are the following : Naphthalin Compounds. Naphthalin is a favorite as a moth preventive but is objectionable on ac- count of its odor. Various expedients have been resorted to as shown in these formulas to overcome the odor. Sev- eral other preparations containing naph- thalin are mentioned under "moth pow- ders," "moth species," etc. I. Cedar-Naphthalin : Oil of cedarwood fl.oz. 2 Naphthalin, flakes av.lb. 5 The oil destroys to a considerable ex- tent the naphthalin odor and is itself a good moth preventive. II. Compound Naphthalin Powder : Naphthalin av.oz. 8 Filler av.oz. 4 Colocynth av.oz. 2 Insect powder av.oz. \ l / 2 Borax av.oz. 1 DOMESTIC UTILITIES. 1137 Snuff av.oz. y 2 Oil of turpentine fl.dr. 4 Reduce the solids to powder, mix well, spread out on a sheet of paper and sprinkle the oil evenly over the whole. Then mix again and pass through a fine sieve. It should be put in a tight package, preferably the usual insect powder cans. The "filler" is usually bran, sawdust, corn meal, etc. If de- sired, perfume can be added to this powder, oil of cedarwood being very appropriate, and also adding materially to its efficacy. III. Xaphthalin-Camphor : Camphor gum part 1 Naphthalin parts 3 Melt together carefully on a water- bath, then pour into molds, and form into cakes. — D. IV. A variation of the preceding is this: Camphor part 1 Paraffin wax parts 5 Naphthalin parts 10 H. V. Perfumed Naphthalin-Camphor : Camphor av.oz. 3 Naphthalin av.oz. 9 Cumarin gr. 3 Oil of neroli drops 10 Oil of mirbane drops 10 Prepare like the preceding. Moth Paper. This is used for wrapping about the clothing or other articles to be protect- ed, or sheets may be laid in the cloth- ing : Naphthalin . . .av.oz. 4 Paraffin wax av.oz. 8 Melt together, and while still warm paint with a rather broad brush upon unsized paper. — H. Moth Powders. These may be sprinkled among the clothes before the latter are packed away for the summer. Or they may be enclosed in little bags like sachet-pow- der bags and laid among the clothes. Or the powder may be laid between two sheets of paper and then laid in the clothing. Capsicum, powder av.oz. 1 Naphthalin, powder av.oz. 4 Insect powder av.oz. 5 Mix well. Use as described above. — D. II. Naphthalin av.oz. 8 Starch av.oz. 2 Orris root av.oz. 2 Patchouly herb . . av.oz. 2 Camphor ^_ av.oz. 2 Reduce all to powd er and mix well. III. Patchouly av.oz. 5 Valerian av.oz. 2Y2 Orris root av.oz. 2.Y-2. Sumbul root av.oz. 2Y2 Camphor av.oz. 2 Naphthalin av.oz. 1 Scotch snuff av.oz. 1 Oil of cassia fl.oz. 1 Oil of eucalyptus. fl.oz. 1 Reduce the solids to fine powder and incorporate with the remaining ingre- dients. Moth Species. This is to be used like moth powder. Patchouly, cut . . . av.oz. Rosemary, cut . . . Thyme, cut Sa°re, cut Naphthalin Oil of mirbane... Oil of turpentine. Alcohol av.oz. av.oz. av.oz. av.oz. fl.dr. fl.oz. fl.oz. 4 4 4 4 4 1 TO Dissolve the naphthalin and oils in the alcohol by the aid of heat, and sprinkle the solution while hot upon the mixed herbs or leaves. Introduce the mixture into bags or suitable size and lay them between the clothes to be pre- served, which should be firmly wrapped, securely packed, and kept in a cool place. — D. MOUNTING PASTE for Photo- graphs. See Paste for Mounting Photographs. MUCILAGES AND PASTES. See also under heading Pastes. I. What is a satisfactory adhesive and was the first mucilage used is muci- lage of acacia, which may be made sat- isfactorily according to the U. S. P. process. A preventive must be added such as oil of clove or wintergreen or other suitable antiseptic. 1138 THE STANDARD FORMULARY On account of the expensiveness of gum arabic, mucilages are made with numberless other substances as may be observed in the succeeding formulas. Gum ghatti may also replace the gum arabic. II. Dextrin, being cheap and pos- sessing strongly adhesive properties, is largely employed for making a muci- lage, yellow dextrin being the kind mostly used. Dextrin, vellow av.oz. 4 Water fl.oz. 8 Heat the water, add the dextrin grad- ually with constant stirring, and con- tinue the heat utnil the dextrin is dis- solved. One fluidounce of acetic acid may be added to the water before heat- ing, and to the solution may be added the same amount of alcohol to insure preservation. However, neither one is necessary if carbolic acid or an essen- tial oil, like oil of clove or wintegreen be added. This mucilage may be thin- ned when it becomes thickened by ex- posure, by dilution with water. A small amount of glycerin added to the muci- lage will prevent curling of the paper. See Xos. IV for paste made with white dextrin. III. Dextrin, yellow av.oz. 8 Water fl.oz. 12 Syrpy glucose dr. 3 Aluminium sulfate (not alum) dr. i l / 2 Mix the dextrin with the water, add the glucose and aluminium sulfate, and heat the mixture to about 90 C, when it will become transparent and thin. — D. IV. White dextrin av.oz. 7 Water fl.oz. 17 Diluted acetic acid fl.dr. 10 Glycerin fl.dr. 10 Oil of clove drops 16 Mix the dextrin with 7 fluidounces of warm water, then add 10 fluidounces of boiling water, and boil the whole for 5 minutes. Allow to cool, and add the other ingredients. V. flour 1 1 30 24 2 30 J. K. Williams' formula for Paste : Rye flour av.oz. Alum, powder dr. Borax, powder dr. Boric acid gr. Water fl.oz. Acetic acid, 36% fl.oz. Oil of sassafras m. Thoroughly mix the flour, alum, borax and boric acid, add 8 fluidounces of cold water and stir or beat until free from lumpiness. Then add the acetic acid and 16 fluidounces of boiling water, all at once, and stir the whole until smooth. Then heat over a hot fire to break up the starch globules which will be indi- cated by the bluish tint on top, stirring thoroughly meanwhile to prevent scorch- ing. Be careful not to heat too long. Allow to cool and incorporate the oil. Transfer to a covered jar and when wanted for use reduce with boiling wa- ter, about 1 part of paste to 2 of water, adding the water slowly and in a boiling condition and beating the mixture till smooth. VI. E. W. Runyon's label paste: Flour av.oz. 4 Xtiric acid m. 40 Oil of clove m. 5 Carbolic acid m. 5 Water fl.oz. 16 Thoroughly mix the flour and water, strain through, a sieve, add the nitric acid, apply heat until thoroughly cook- ed, and when nearly cold add the oil of clove and carbolic acid. In dry climates the addition of 5% of glycerin prevents it from drying too soon in the mucilage pot. VII. Bradford's formula : Wheat flour av.oz Alum av.oz Salicylic acid dr. 1 Water pints 2 Dissolve the alum and acid in the wa- ter and add the flour. Rub to a smooth mixture, strain through a cheese-cloth, and wash the residue left on the strain- er with the strained liquid until the flour is all through. Xow apply heat, stirring constantly meanwhile. The de- l A DOMESTIC UTILITIES. 1139 gree to which it is to be cooked will de- pend on the purpose to which it is to be put. If intended for bottling, cook just enough to thicken but not so heavy that it cannot be poured. But if it is to be stored, the heat should be continued un- til the paste takes on a bluish tint and becomes stiff and almost dry. Great care must be taken to prevent scorching or burning. When cooked in this way, it may, when cold, be cut in chunks and carried about in paper. When required for use it is to be thinned with water. If the heat be still further continued cautiously until all the water is driven off, the paste can be reduced to powder, which will keep indefinitely and is ready for use at any time by adding water. This paste may be used by paperhang- ers. If the salicylic acid be replaced by 2 drams of caustic soda, the product will serve for applying labels to tin. MUCILAGE, Elastic or Flexible. Gum arabic av.oz. 8 Water fl.oz. 16 Salicylic acid gr. 40 Soft soap dr. 2 Glycerin dr. 2 Alcohol fl.oz. iy 2 Dissolve the gum in the water ; also dissolve the acid in the alcohol, mix with the soap and glycerin, and shake the whole thoroughly with the gum so- lution. This mucilage keeps well and when it dries remains elastic without any tend- ency to cracking. MUCILAGE, Stick or Bar. (Mucilage Pencil.) Mucilage, in the form of sticks, is much used in architectural and mechan- ical drawing for attaching the drawing paper to a board, and is generally spok- en of as mouth or lip glue. In making such a glue, only a very pure form of gelatin or glue should be used, as the least taste, would prove disgusting when the glue is moistened with the lips. Su- gar is generally added, not for the pur- pose of sweetening the glue, but in or- der to render it more easily soluble when it is to be used. This probably 72 is brought about by the sugar prevent- ing the glue from becoming too dry and hard. Some even use a good quality of glue without any admixture whatever, but this requires more rubbing when it is applied, although it holds better than that to which sugar has been added. The sugar may be replaced by glycerin. I. Glue, best av.oz. 4 Isinglass av.oz. 1 Brown sugar av.oz. 1 Water sufficient Soak the glue and isinglass in water until soft. Pour off the superfluous water, and add the sugar. Melt the whole together with a gentle heat and allow to evaporate utnil quite thick. Pour into a flat-bottomed dish that is quite cold, preferably placed on ice, and when solid cut the glue into the desired shape. II. Isinglass av.oz. 1 White glue av.oz. 1 Sugar dr. 2 Tragacanth dr. 2 Water fl.oz. 1 Boil the whole together until when cold the mixture has the appearance of glue. Then form into rolls for use. If desired the glue, made according to either of the above formulas, may, while hot, be poured into suitable molds that have been previously well chilled. III. Glue, best av.oz. 12 Sugar av.oz. 5 Water sufficient Soak the glue in water over night, and dissolve it by heat in the smallest possible quantity of water. Add the sugar to the hot solution, and dry the composition, like jujube paste, in oiled molds. MUELLER'S FLUID (for Preserv- ing Anatomical Specimens). Potassium bichromate, gr. 160 to 190 Sodium sulfate gr. 80 Water fl.oz. 16 Mix and dissolve. 1140 THE STANDARD FORMULARY NAPHTHALIN PAPER. See under Moth Preventives and De- stroyers. NICKEL PLATING. See Plating with Gold, Silver, etc. NUTRIENT GELATIN. Gelatin av.oz. i Extract of beef dr. 3 Distilled water fl.oz. 29 Dissolve the gelatin and extract in the water, filter, heat to boiling, and divide among test tubes which have previously been treated with boiling water. Close the cylinders with plugs of cotton, which has previously been heated for some time to a temperature of 150 C., then set aside for 4 weeks. Only the gelatin mixture which re- mains clear is to be used; if it becomes turbid, it is to be boiled again and again until it remains clear. Another nutrient gelatin is produced by dissolving 1 part of gelatin in 20 parts of infusion of hay. — D. These are used for bacteriological work. OIL CLOTH, To Furbish. Paraffin wax av.oz. 5 Oil of turpentine rl.oz. 16 Dissolve the paraffin in the oil by the aid of a gentle heat, and apply with a sponge or piece of flannel while warm. Let it remain on the oil cloth for 24 hours, then polish with flannel. OILS, Bleaching of. See Bleaching of Linseed and Poppy Seed Oils. OILED PAPER. See Paper, Oiled. OILY BOTTLES, To Clean. See Bottles, Cleaning of Greasy. OLIVE OIL, Denatured. See Denatured Olive Oil. "OXIDIZING" SILVER. See Silver, Oxidizing of. OZONIN. Resin av.oz. 5 Oil of turpentine fl.oz. 8 Potassium hydrate av.oz. 1 Water " fl.dr. 13 Hydrogen peroxid fl.oz. 3^4 Dissolve the resin in the oil, add the potassium hydrate first dissolved in the water, and then mix with the hydrogen peroxid. The resulting jelly when ex- posed to light for 2 or 3 days changes into a thin liquid known as ozonin, which in the proportion of I part in 1000 of water acts as a bleaching agent on fibres, wood, straw, paper, cork, etc., acting well in both acid and alkaline solution. PAINT, BLACK, Glossy. See Bicycle Paint. PAINT, BRONZE. See Bronze Paint. PAINT, Glossy or Enamel, White. Orange shellac av.oz. 15 Copal resin av.oz. 5 Venice turpentine av.oz. I Linseed oil, raw fl.oz. 4 Alcohol pints 10 Mix, and add 4 or 5 pounds of zinc white or other white pigment. Another enamel paint may be made by mixing the pigment with a good varnish. PAINTS, How to Mix for Colors. White and black makes gray. Red and black makes brown. Lake and white makes rose. White and brown makes chestnut. White, blue and lake makes purple. Blue and lead color makes pearl. White and carmine makes pink. Indigo and lampblack makes silver gray. White and lampblack makes lead color. Black and Venetian red makes choco- late. White and green makes bright green. Purple and white makes French white. Light green and black makes dark green. White and Green makes pea green. White and emerald green makes bril- liant green. Red and yellow makes orange. White and yellow makes straw color. DOMESTIC UTILITIES. 1141 White, blue and black makes pearl gray. White, lake and vermillion makes flesh color. Umber, white and Venetian red makes drab. White, yellow and Venetian red makes cream. Red, blue, black and red makes olive. Yellow, white and a little Venetian red makes buff. PAINT, LUMINOUS. The process of making luminous paint depends on the prone, ty, possessed by certain substances, of absorbing light during exposure to sunshine or other very powerful sources of light, and giv- ing it off again in the darkness, a prop- erty which is sometimes, though incor- rectly, called "phosphorescence." The list of substances possessing this prop- erty in a greater or less degree is a long one, and among them the earthy sulfates and sulfids stand preeminent. Numerous processes have been devised for the utilization of this property, many of them covered by patents. One of the first of these was Balmain's process, which consists of a luminiferous sub- stance introduced into ordinary paints. This substance is prepared by heating together certain mixtures of lime and sulfur, and the production of calcium monosulfid. Another French patent rests on the calcination of sea-shells (such as those of the oyster, clam, and other bivalves, cuttlefish bone, etc.) in the presence of sulfur, and the addition to the product of various monosulfids (i. e., calcium, barium, strontium, ura- nium, magnesium, aluminum, etc.). The following is a practical method of procedure: Clean a quantity of oy- ster or mussel shells by washing them in warm suds, rinse in running water, then put them in an open fire and beat them for 30 to 35 minutes, then remove and let cool. When cold, pound them up and remove carefully all grey portions, as they are of no use. Put the remain- ing portion in a crucible, making a thin layer of the burnt shell, and putting on top of it a layer of sulfur, and thus al- ternating until the crucible is nearly full. Screw on the lid and lute to place tightly with a paste' of sand mixed with beer. When this is thoroughly dry put the crucible in a hot fire and heat for an hour. Withdraw the heat, let the crucible cool down spontaneously and when quite cold, remove the top. If the operation has been properly conducted the contents will be a white powder. All grey bits that are still found should be removed, as they only serve to weak- en the luminosity of the product. Now, sift the powder through a muslin sieve, raking it until only a few coarse bits remain. The sifted powder is mixed with gum water and applied in a thin layer to a cardboard, or other surface. When dry another thin layer, let dry and expose to strong sunlight for several hours. The surface will acquire a strong luminosity which, when fresh, will last all night. Another process is the following: Calcined oyster shells or cut- tlefish bone , . . . .parts 4 Caustic lime parts 4 Calcined sodium chlorid parti. Mix and thoroughly incorporate from 20 to 25% of sulfur and from 3 to 7% of calcium, barium, strontium or mag- nesium sulfid. The luminosity may be increased by adding incinerated marine algae. The powder is rendered adhe- sive by means of varnish (alcoholic copal, etc.), collodion, mucilage, etc. Still another process for luminous calcium sulfid is this : Boil for 1 hour 2% ounces caustic lime, recently prepared by calcining- clean white shells at a strong red heat, with I ounce sulfur and 1 quart soft water. Set aside in a covered vessel for a few days; then pour off the li- quid, collect the clear, orange-colored crystals which have deposited, and let them drain and dry on bibulous paper. Place the dried sulfid in a clean gra- phite crucible provided with a cover. 1142 THE STANDARD FORMULARY Heat for V2 hour at a temperature just short of redness, then quickly for about 5 f teen minutes at a white heat. Remove cover, and pack in clay until perfectly cold. A small quantity of pure calcium fluorid is added to the sulfid before heating it. PAINT REMOVERS (from Fabrics). See under the headings Ammonia, Household; Benzin Jelly; Cleansing Preparations ; Glove Cleaners ; Soap, OxGall ; and Stains from Fabrics, Re- moval of. PAINT AND VARNISH Removers. Numerous formulas have been devis- ed for mixtures for removing old paint and varnish from woodwork. A mix- ture of equal parts of benzol, acetone and amylacetate has been recommended. The following has been patented in the U. S. Patent Office: Paraffin parts 4 Hard grease parts 4 Benzole parts 8 Methyl alcohol parts 7 Another mixture for this purpose is this : Acetone parts 16 Wood alcohol parts 16 Benzol parts 5 Benzine parts 3 PANAMA HATS, To Clean. The following method has been rec- ommended : A. Sodium sulfite av.oz. 1 Glycerin fl.dr. 4 Alcohol fl.dr. 1 Water fl.oz. yy 2 Mix and dissolve. B. Citric acid dr. i x / 2 Alcohol fl.oz. 1 Water fl.oz. 9 Mix and dissolve. First sponge the hat with A, then lay it aside in a moist place, preferably a cellar, then apply B, and put away again for 24 hours. Finally iron with a flat- iron, which should not be too hot. Sodium hyposulfite may be used in place of the sulfite. See also Straw Hat Cleaners for other preparations to clean Panama hats. Sodium perborate has been recom- mended lately for cleaning Panama hats. The steps in the process are: (1) Brush the hat in a solution of Castile soap in warm water to remove any su- perficial dirt, rinse, and (2) dip for 5 minutes in a solution of hydrochloric acid in water containing l / 2 ounce of acid to the gallon; (3) transfer to a bath of sodium perborate — 2 ounces to the gallon of lukewarm water — and al- low to remain over night ; (4) rinse out in a solution of oxalic acid of the strength of Yz ounce to a gallon of wa- ter; (5) dry in sunshine or expose to the fumes of burning sulfur in a dry room. PAPER, Barometer or Hygrometer. See Barometer or Hygrometer Paper. PAPER FOR BLUE PRINTS. See Blue Printing Paper. PAPER, CARBOLIZED. Carbolized paper, suitable for the preservation of furs, etc., from moths, can be readily prepared by applying a strong solution of carbolic acid, with a brush or sponge to any unsized paper. A heavy paper will absorb more, and consequently last longer. The paper should be kept in close boxes until wanted, and the consumer directed to place the sheets freely among the arti- cles to be protected, and wrap them tightly in ordinary paper. Carbolic paper may also be prepared as follows : Petrolatum av.oz. 4 Paraffin wax av.oz. 4 Carbolic acid av.oz. 2 Melt the paraffin and petrolatum, add the carbolic acid, allow to cool and so- lidify, and with this prepare carbolized paper, as directed for making waxed and ceresin paper. — D. PAPER, CARBON OR MANIFOLD. The simplest formula is the follow- ing; DOMESTIC UTILITIES. 1143 Lard parts 6 Yellow wax part I Lampblack part I Melt the wax, add the lard and make a thoroughly smooth mixture with the lampblack by trituration. Brush this mixture while warm over suitable paper, and remove the excess with a flannel cloth. PAPER, CERESIN. This may be prepared similarlv to waxed paper. PAPER, HYDROGRAPHIC. See Hydrographic Paper. PAPER, IMPERMEABLE. According to a French patent, im- permeable paper may be made by apply- ing the following mixture on the sur- face : Olive oil, 7 parts ; rapeseed oil, 7; linseed oil, 7. Mix and add white wax, 2, previously dissolved in oil of turpentine, 2 parts. PAPER, OILED. Brush sheets of paper over with boil- ed oil and suspend them on a line to dry. PAPER, PARAFFINED. This may be prepared like waxed paper, or the paper may be drawn through melted paraffin; or, a better way is to melt 8 av. ounces of paraffin, remove from the fire, add 16 fluidounces of benzin; draw the paper through this, and then dry. PAPER, Parchment, for Bottles. The transparent paper used by manu- facturers for "finishing off" pharmaceu- tical preparations is the kind known as "parchment," though of course it is not the real parchment, which is very rare and expensive. In wrapping the bot- tle, use paper of the proper size, apply flour or other white paste to the edges, roll the paper neatly around the bot- tle, wet the top portion of the paper by dipping in water, allow the excess of water to drain off, then fold the paper over and press it upon the bottle. The paste applied to the edges secures the back seam. PAPER, RAZOR. See Razor Paper, PAPER, RESIN. Gum turpentine av.oz. 1 Benzine fl.oz. 16 Dissolve the gum in the benzine by maceration, and spread the mixture on paper by means of a brush. It is then dried by hanging up ; the benzine odor may be removed by subjecting to the heat of a drying oven. PAPER, TRACING. I. Apply with a brush a varnish com- pound of equal parts of balsam of fir and oil of turpentine to smooth unsized white paper, and hang up the sheets to dry. II. Rub the paper with a mixture of equal parts of cottonseed oil and oil of turpentine; dry immediately, by rubbing it with wheat flour, and then hang up for 24 hours to dry. If washed over with ox-gall, and dried, it may be writ- ten upon with ink or water colors. PAPER, WAXED. Place strong white paper on a hot iron plate and rub it well with a lump of white wax, the excess to be removed by means of a cloth pad. PASTE, LIBRARY. (Photo-Library Paste.) See also the Mucilages. I. Edel's process : White dextrin lbs. 5 or S r A Water gal. 1 Oil of wintergreen m. 30 Oil of clove m. 30 Heat the water to 160 F., then turn off the heat, add the dextrin and stir until dissolved. When cool, add the oils and stir well. Then pour into bottles, cork and put away in a cool place. After 2 to 4 weeks the mixture will alter or "ripen" so that a creamy paste is ob- tained. If the bottles are put into a refrigerator at a temperature of about 40 R, the "ripening" will occur in a week or less. 1144 THE STANDARD FORMULARY A patent was also granted for a prep- aration like this in 1895. II. Ebert's formula : Corn starch av.oz. 2 Gelatin av.oz. 24 Water fl.oz. 16 Oil of clove drops 16 Incorporate the starch with the water, add the gelatin, and heat the whole on a water-bath until a uniform jelly-like compound results. When nearly cold, stir in the oil. III. White dextrin av.oz. 12 White sugar av.oz. 3 Alum av.oz. ]/ 2 Water fl.oz. 20 Formaldehyde m. 10 Oil of wintergreen m. 10 Rub the solids to powder, mix well, and add the water in a boiling condi- tion. Then allow to cool, rub in a mor- tar to a smooth consistency, and finally incorporate the formaldehyde and oil. PASTE for Mounting Photographs. I.' Gelatin av.oz. 1 Alcohol fl.oz. \]/ 2 Glycerin fl.oz. y 2 to 1 Water fl.oz. 4 Soak the gelatin in cold water for an hour or more, then drain off as much water as possible, and add to the alcohol contained in a wide-mouthed bottle. Now add the glycerin, the quantity to vary as the gelatin is of the soft or hard kind. Put the bottle in hot water, agitating occasionally until the glycerin is dissolved. II. Arrowroot av.oz. 1 Gelatin gr. 50 Alcohol fl.oz. 1 Water fl.oz. 10 Soak the gelatin in the water, add the arrowroot which has previously been mixed with a small quantity of the water and boil for 4 or 5 minutes. After cooling, add the alcohol and a few drops of carbolic acid or oil of clove. PASTE in Powder Form. A patent was granted some years ago for a paste consisting of flour, starch, or other farinaceous substance, with an alkali, preferably caustic soda or pot- ash, or other strongly alkaline sub- stance. If the flour be mixed with any of these substances in the form of pow- der in the proper proportions they form a compound which, when mixed with water, will soon assume the consistence of a paste, and will become soluble in water. The actiorr of the alkali on the flour bursts the starch cells and digests or dissolves it, increasing its bulk and reducing it to a paste, which may be thinned by the addition of water or thickened by the addition of more of the alkali and flour. These compounds are sold as powders, to be mixed with water by the user. The following formula has been given : Flour parts 21 Caustic soda in powder. .. .parts 2 In place of the caustic soda, pulver- ized caustic potash may be used. Other forms of alkali — such as strong soda ash — may also be used, but the quantity must be considerably increased until sufficient to digest the flour. A formula said to answer better for all purposes is the following modifica- tion of the above : Flour, starch or other farin- aceous substance parts 21 Caustic soda (or potash), in powder parts 2 Ammonium sulfate parts 2 When using this, add water. The ammonium sulfate is used as a neutralizing agent and counteracts the strong effects of caustic soda on col- ored or tinted papers. PASTE to Stick Labels on Tin. Many expedients have been offered to enable paper labels to adhere to tin con- tainers. A simple plan is to roughen the surface of the tin by rubbing with a piece of sand or emery paper, then ap- plying the label in the usual manner. Or apply to the surface of the tin a slight coating of a resinous tincture, such as tincture of benzoin or myrrh, DOMESTIC UTILITIES. 1145 allowing the tin to dry and then apply- ing the label as before. Or rub the tin with hydrochloric acid or with tincture of iron and then applying the label as before. If solution of silicate of sodium be used instead of mucilage or paste, the label will adhere indefinitely, but this preparation has some disadvantages, such as its strong alkalinity and the dif- ficulty of applying it satisfactorily. It is also said that labels peel off from the tin surface because of the dry- big of the paste and that if some ingre- dient were present in the paste which would cause it to remain permanently moist, this peeling off would not occur. Such substances are glycerin and cal- cium chlorid. Another substance which has been suggested as a good addition to ordinary paste to make it adhere to tin is solution of antimony chlorid. Preparation No. VII under the head- ing Mucilages and Pastes is excellent for applying labels to tin. PENCILS, COLORED. See Colored Pencils. PENCILS FOR WRITING ON GLASS. Spermaceti parts 3 Talcum parts 3 Yellow wax parts 2 Red lead parts 6 Caustic potash part 1 PESTLE HANDLES, To Cement. The handles of wedgewood pestles are usually inserted with glue, which soon comes loose. When the handle does come loose, it may be reinserted in various ways. One method is to melt some orange shellac at a gentle heat, pour the melted mass into the cavity, then push in the handle. In a moment or two, the excess of shellac which has exuded will harden and may be scraped off. Equal parts of caoutchouc and shellac are used in the same manner. Another plan is to make a thick paste of litharge and glycerin, using this in the same manner as the melted shellac. Instead of litharge and glycerin, a mix- ture of calomel and mucilage of acacia may be used. Before attempting to use any of these substances, the cavity of the pestle and the end of the pestle handle should be freed from glue as much as possible. PETROLEUM SOAP. See Soap, Petroleum. PHARAOH'S SERPENTS. This curious chemical toy, also known as "eggs of Pharaoh's serpents," is pre- pared as follows: Dissolve mercury in diluted nitric acid, being careful that there shall be an excess of mercury present. When the action of the acid has ceased decant the solution, and pour it into a solution of ammonium or potassium sulfocyanid. A precipitate of mercury sulphocyanid is formed which should be washed, col- lected, and dried. Then for every pound of this substance, take one ounce of gum tragacanth, soak it in water to soften thoroughly, transfer it to a mor- tar, add the dried precipitate, and make the whole into a paste by the addition of sufficient water. The mass is then pressed into molds of conical shape and dried. When these are ignited by the application of a match at the conical end they form an enormous volume of ash which proceeds in great coils from the body of the mass, and which by its serpentine movements as it is formed, has suggested the name. This substance is not altogether free from danger- in its use because mercu- rial fumes are formed during combus- tion of the mass. On this account sev- eral substitutes have been suggested. One of these which is almost as good as the original and which is not poisonous is prepared as follows: Potassium bichromate av.oz. 2 Potassium nitrate av.oz. 1 Sugar av.oz. 3 Pulverize each of the ingredients sep- arately, and then mix them thoroughly. Make small paper cones of the desired 1146 THE STANDARD FORMULARY size and press the mixture into them. When quite dry they are ready for use. They should be kept from moisture and light. PHOSPHORUS PASTES. These are used mainly for the exter- mination of rats and roaches, but are equally effective against mice, water bugs, and other vermin. The phosphorus is either melted in warm water, liquefied with sulfur, or dissolved in carbon disulfid, then mixed with a fatty substance like lard, suet, or oil, and finally with a floury substance to give the requisite consistency. Ow- ing to the ready combustibility of phos- phorus, great care must be exercised in handling it, especially when it is melted in water by the aid of heat. Sometimes these pastes decompose ("sour") easily, especially if they con- tain any saccharine substance like mo- lasses. In using these pastes, they are smear- ed into all crevices and corners to com- bat roaches ; for rats they are spread on thin slices of bread and cheese which are then cut up into small pieces and strewed about in appropriate places. I. Rother's formula : Phosphorus av.oz. I Starch av.oz. 4 Flour av.oz. 12 Glycerin fl.oz. 12 Water . . . . fl.oz. 24 Make a smooth mixture of the starch, flour, glycerin and 20 fluidounces of water, straining through a No. 60 sieve if necessary, transfer to an enameled- irori evaporating dish, and apply heat, best by means of a sand-bath, until a plasma begins to form, stirring or beat- ing meanwhile with a pestle or paddle ; then take the vessel from the fire and stir as before while the plasma forms, so as to evenly divide it. After a few minutes reapply heat, stirring briskly until the plasma has completely formed, then set aside to cool, stirring occa- sionally. Xow place 3 ounces of the plasma, thoroughly mixed with the remaining 4 fluidounces of water, into a porcelain measure of the capacity of one pint, set this into nearly boiling hot water, and when the mixture has become suf- ficiently hot, drop in about I dram of the phosphorus. When this has fused, agitate the whole thoroughly with a spatula or pestle, and incorporate the remainder of the phosphorus in the same manner. By this manipulation the phosphorus is effectively extinguished without the risk of coming in contact with the air in an inflammable condi- tion. After this thicken the phosphoric mixture with more of the reserved plasma and finally incorporate it thor- oughly with the remainder of the plasma. II. Scoville's formula : Phosphorus av.oz. 1 Lard av.oz. 6 Barium carbonate av.oz. 6 Water fl.oz. 6 Wheat flour av.oz. 12 Molasses av.oz. 12 Make a dough of the flour and water and incorporate the lard. Place the mo- lasses in a wide-mouthed bottle, add the phosphorus and heat upon a water-bath until the latter is melted, stir well to suspend the phosphorus, then add to the dough, and incorporate quickly. Finally stir in the barium carbonate and trans- fer to suitable bottles. The mass is lia- ble to take fire while incorporating the phosphorus, which should be done in an open space, the hands being protect- ed meanwhile by wrapping in wet cloths. III. Patton's formula : Phosphorus av.oz. r Corrosive sublimate dr. 1 Table salt av.oz. 1 Glycerin fl.oz. VA Wheat flour av.oz. S l / 2 Water fl.oz. 24 Beat the flour with the water to a smooth' mixture, add the other ingredi- ents and heat the mixture very cauti- ously, Stir meanwhile constantly with a DOMESTIC UTILITIES. 1147 wooden paddle so as to obtain a uni- form paste when all the starch cells are broken. When the paste is sufficiently solid, a small quantity of Venetian red may be added for coloring purposes. Finally put into suitable wide-mouthed bottles. PIANO COVERS (Rubber), To Clean. See Rubber Piano Covers, To Clean. PIANO POLISH. See Furniture Polish. PICTURES, To Transfer. A saponaceous liquid is generally used to transfer pictures from newspapers, magazines, etc., to glass, porcelain or similar articles, as in the following: I. Soft soap dr. i Potassium carbonate gr. 30 Distilled water fl.oz. 4 Mix and dissolve. The print is laid on a flat surface, such as a drawing board, and moistened with the liquid. The paper on which the reproduction is required is laid over this, and then a sheet of thicker paper is placed on the top, and the whole rub- bed evenly and hard with a blunt in- strument, such as the bowl of a spoon, until the desired depth of color in the transferrer is obtained. Another and more artistic process is to cover the print with a transparent sheet of mate- rial coated with wax, to trace out the pictures with a point and to take rub- bings of the same after powdering with plumbago. II. Hard soap dr. 2 Glycerin fl.dr. 1 Alcohol fl.oz. 1 Water fl.oz. 2 For the soap use Castile or any other kind of hard soap. Dissolve it in the water by the aid of heat, then add the other ingredients. Use this like the preceding. III. Common yellow soap dr. 2 Water fl.oz. 4 Oil of turpentine. ..,,,,,,. -fl.dr. 6 Dissolve the soap in the water by the aid of heat, and when the solution is nearly cold add the oil, and shake thor- oughly together. This fluid is applied liberally to the surface of the printed matter with a soft brush or sponge (be- ing careful not to smear the ink, which soon becomes softened) and allowed to soak for a few minutes; then dampen the plain paper on which the transfer is to be made, place it upon the engraving and subject the whole to moderate pres- sure for about one minute. On separat- ing them a reversed transfer will be found on the paper. PITCH FOR BOATS. Pine or coal tar .gall. 1 Rosin av.lb. 3 Melt the rosin and add the tar. The product made with coal tar will chill the quickest. PLANT FOOD. See Fertilizers. PLANT INSECT EXTERMINA- TORS. See Insecticides for Plants. PLASTER OF PARIS FORMULAS. 1. To Make Plaster Set Hard— -Mix best plaster of Paris with about 10% (more or less, according to effect ascer- tained by preliminary experiment) of very fine powdered marble (calcium carbonate). Or add to it about 6% of powdered alum, or about the same amount of ammonium chlorid, before mixing it with water. 2. To Make Plaster Set Slower.— Mix it with 2 to 4% of powdered al- thaea root before adding the water. This not only retards the hardening of the plaster, but also enables it to be cut, filed, sawed and turned. An addition of 8% of althaea powder retards the complete setting of the plas- ter for about one hour, so that the mass can be used for any purpose where it is to remain plastic during at least a portion of that time. The addition of fine slacked lime will also retard the setting of plaster. The time of setting 1148 THE STANDARD FORMULARY may be regulated by changing the rela- tive quantities of lime and plaster of Paris. PLATING WITH GOLD, SILVER, TIN, ETC. A number of processes and formulas are here given, all of which are highly recommended. The deposition of one metal upon an- other may be made in several ways. What is now the most common and us- ually most satisfactory method of de- position, generally known as "plating," is by means of the electric current, this method being known as "electroplating." Another method of deposition, which is a very inferior process, is what is tech- nically known as "washing." This con- sists in the application of a solution of a salt of a metal which is to be deposit- ed by means of a cloth. The coating of metal deposited is so infinitely thin that it very quickly wears away, revealing the inferior material beneath. I. Gold "washing" : A (liquid form). Gold chlorid dr. I Potassium cyanid dr. 3 Distilled water oz. 1 Precipitated chalk sufficient Dissolve the gold chlorid in 1 fluidram of water, and the potassium cyanid in the remainder of the water; mix the two solutions and add enough precipi- tated chalk to make a thin paste. After thoroughly cleaning the object to be gilded, and freeing it from grease, etc., apply this paste with a camel's-hair pencil evenly over the surface, keeping the liquid well stirred meanwhile. Let dry slowly at ordinary temperature. When dry, put in an oven and heat to 60 or 70 C. Wash off with clean wa- ter, dry and finish by going over the surface with a burnisher. B (powder form). Gold chlorid gr. 90 Potassium cyanid gr. 280 Potassium bitartrate gr. 24 Prepared chalk av.oz. 1 Mix the ingredients intimately; add water to make a moderately thick paste ; rub with a bit of flannel. The surface must, of course, be thoroughly cleaned. II. Silver "washing" (for brass only) : A. Silver nitrate av.oz. Yi Potassium cyanid av.oz. 1 Precipitated chalk av.oz. 1 Distilled water fl.oz. 6 Dissolve the silver nitrate and potas- sium cyanid each separately in a por- tion of the water, mix the two solu- tions, and add the chalk: In iJfeing, clean the article to be coated so as to free it from grease and tar- nish, then rub with the liquid applied on a cloth. B. Silver nitrate gr. 165 Ammonia water fl.dr. 3 Sodium hyposulfite dr. 5 Precipitated chalk dr. 5 Distilled water fl.oz. 6 l / 2 Dissolve the silver salt in a portion of the water, the hyposulfite in the re- mainder, mix the two solutions, and add the ammonia and chalk. This is to be used like the preced- ing. C. Silver chlorid dr. 1 Cream of tartar dr. 6 l / 2 Sodium chlorid dr. 3 The powder is made into a cream with water, and the article to be plated is either covered with the paint by means of a brush or immersed in the mixture for a short time; then, after being dried, it is rubbed off and the article polished with prepared chalk. — H. The silver chlorid may be made by precipitating a solution of silver nitrate, about 1 in 20, with hydrochloric acid, previously acidulating the solution with nitric acid. Collect the precipitate on a filter, wash it with water, and dry it. D. Silver chlorid dr. 3 Sodium chlorid. . . , , , . ,dr. 3 DOMESTIC UTILITIES. 1149 Prepared chalk dr. 2 Potassium carbonate dr. 6 Powder thoroughly and mix well. To use the preparation dip a moist- ened rag in it and apply it to the arti- cle to be silvered, which latter should be thoroughly freed from grease, etc., before applying the powder. This powder should be put up in paraffin paper as otherwise it will at- tract moisture from the air and be- come liquid. III. Silvering objects by dipping: This is a purely chemical method, the galvanic current not being used for depositing the silver on the objects. It is especially adapted for small ob- jects made of brass and copper, such as buttons, nails, wire, screws, pins and needles, etc. The bath is made l.s follows : Silver nitrate gr. 100 Potassium cyanid dr. 6 Water, distilled fl.oz. iSy 2 Dissolve the salts separately in the distilled water, then mix the solutions and warm on a water bath to about 50 to 6o° C. The objects to be silvered are placed in a basket, or hung from a wire frame, and dipped in the warm bath. If the objects are perfectly clean, presenting a metallic surface, the sil- ver will be deposited immediately. If the metallic surface of the objects pre- sents a mat surface, a mat silvering results. When the surface to be sil- vered shows a bright metallic surface of high luster, the silvered articles come out with _a polish and bright surface. If the operator finds the bath gives poor results, it is useless to add fresh salts; the liquid must be thrown away and a fresh solution has to be made. This method of silvering depends on the greater solubility of the copper and zinc over silver, and these metals must replace the silver in solution. Unfort- unately, when an object is silvered by this method only a very thin film of metal is deposited. When a heavier plating is desired, the electro-plating method must be resorted to, but, for small pins, trinkets and the like, where only a thin deposit is required, this method is advantageous, since so many objects can be treated at one time. IV. Nickeling : There is no reliable method of de- positing nickel from its cold solution, as in the foregoing cases, but a thin and adhesive coating may be given arti- cles of brass, iron, etc., by the follow- ing process : Boil in a copper vessel a saturated solution of zinc chlorid and an equal quantity of water. While boil- ing add hydrochloric acid, drop by drop, until the precipitate at first thrown down is again completely redissolved. Now add zinc in powder, until the bottom of the kettle is nearly covered with a precipitate of zinc. The bath is now ready for the ' addition of a salt of nickel, and either the sulfate or the nitrate may be used. Add it in suffi- cient quantity to give the bath a strong green color. The articles to be nickeled are now hung in the bath by means of a zinc wire, or a strip of sheet zinc, and a few pieces of the latter are thrown in along with them. Raise the heat to a strong boil and continue it for several minutes, or until the arti- cles are covered with a bright coating of nickel. The articles should be thor- oughly cleaned and freed from grease before being put in the bath. When finished, rinse and then rub well with precipitated chalk. V. Platinizing : Platinum chlorid, 1 part; sodium chlorid, 8 parts; distilled water, 100 parts. Bring to a boil, and put the articles to be platinized, first thoroughly cleaned, in the vessel. Keep at a mod- erate temperature, and in the course of 3 or 4 hours the platinizing will be completed. Polish with chamois. There is as yet no known method of depositing aluminium by a process similar to any of the above. VI. Brass scale pans, or any other metallic substance capable of taking a 1150 THE STANDARD FORMULARY deposit of silver may be plated in vari- ous ways. Here is a method recom- mended by Kayser : It is absolutely necessary that the article to be plated shall present a perfect metallic surface, free from ox- ids, dirt, grease, etc.; it must be thor- oughly scoured, if necessary, with the intervention of acids, and afterwards carefully washed. It is then to be dip- ped into a solution prepared by mak- ing a saturated aqueous solution of bi- sulfite of sodium, and adding to the lat- ter so much of a solution of nitrate of silver (30 parts in 100) that there are 6 parts of the silver salt for every 100 of the bisulfite.. The following would be a more simple way to state the pro- portions : Sodium bisulfite av.oz. 10 Distilled water. . .enough to dissolve Silver nitrate gr. 264 Distilled water fl.oz. 2 Dissolve and mix the two solutions. Allow the article to remain in the mixture until it is properly coated, then take it out ; wash it with water in which a little sodium carbonate had previ- ously been dissolved ; finally wash with pure water, and dry in sawdust. POLISH FOR STOVES. See Stove Polish or Blacking. POLISHING CLOTHS. The so-called polishing cloths are made in different ways. The simplest is to dissolve 1 ounce of oxalic acid in a gallon of water, and sift into the solu- tion one pound of whiting. Saturate pieces of canton flannel, about 18 inches in this liquid, which is to be kept well stirred, wring out the cloth somewhat, and allow it to dry. Then smooth out the cloth, fold it, and insert in an en- velope. Another plan is to use a mixture of 2 parts of white castile soap, 1 part of jeweler's rouge, and 20 of water. Dissolve the soap in the water by the aid of heat, adding water from time to time if necessary; and then incorporate the rouge. Impregnate pieces of woolen cloth, which may be red, in the same manner as the preceding. Instead of the cloth, chamois leather may be used which will prove more durable for many purposes. Sometimes two kinds of cloths are used in conjunction. The first is im- pregnated with a mixture of flour of emery, 1 part, soap, 2 parts, and water, 10 parts, the second with a mixture of tripoli or jeweler's rouge, 1 part, soap, 2 parts, and water 10 parts. The first cloth is used as a scourer to remove the oxidized surface while the second cloth is the polisher proper. POLISHING LIQUIDS. A patent has been taken out in France for a liquid polish, which, it is claimed, is of wide applicability and great ex- cellence, giving a high polish to varn- ished or polished surfaces of almost every description from floors, oil cloths, linoleum furniture, etc., uo to art mar- bles. The formula is as follows : Yellow wax parts 30 Oil of lavender part 1 Ammonia water part 1 Alcohol parts 2 Benzin, deodorized parts 200 If a darker color be desired, a very small quantity of aniline brown may be added, dissolve in the alcohol. POLISHING PASTE. See Putz Pomades. POLISHING POWDERS. Under this heading are mentioned powdery mixtures used in polishing dif- ferent metals. These powders must always be impalpably fine, particularly such as are used to polish silver and gold ware. I. Chalk av.oz. 10 White bole av.oz. 4 Lead carbonate av.oz. 5 Magnesium carbonate av.oz. 1 Iron oxid av.oz. 1 This mixture is best adapted to brass and copper. II. Calcined magnesia av.oz. 9 Jeweler's rouge (crocus martis) ,.,..,.,.. ,av,oz. 1 DOMESTIC UTILITIES. 1151 This mixture is recommended for polishing silver; it should be used dry. — D. III. Calcined magnesia av.oz. 8 Jeweler's rouge (crocus martis) av.oz. 8 This mixture is recommended for polishing gold; it should be used dry. — D. IV. Magnesium carbonate av.oz. 4 Chalk av.oz. 4 Jeweler's rouge av.oz. 7 V. Tartaric acid av.oz. 3 Chalk av.oz. 3 Alum av.oz. 1 Reduce all to very fine powder and mix well. This is recommended for silver. Ap- ply with a moistened rag, then polish with a piece of chamois. VI. A popular preparation made in Germany was found upon analysis to consist of 9 parts of tripoli and 1 part of tartaric acid. POLISH FOR SHOES. See Shoe Blacking, Liquid; Shoe Blacking, Paste Form; and Shoe Dress- ing, Tan or Russet. PORCELAIN LETTERS, To Fasten to Windows. See under Enameled Letters. PUTTY, GLAZIER'S. Mix whiting with boiled linseed oil to form a stiff paste. PTTTZ POMADES. By this term are signified pasty or fatty mixtures intended especially for polishing copper and brass ; these mix- tures may be used on steel, but should never be used on silver or gold. The fatty substance present consists of a fixed oil — oleic acid, lard, petro- latum, palm oil, lard oil, etc., mixed with tripoli, rotten stone, emery, jew- eler's rouge (also called crocus martis), pumice stone, etc. ; the whole being flav- ored, as a rule, with oil of mirbane (nitro-benzol or artifical oil of bitter almond). The powders must be in a very finely divided condition ; it is, in fact, advisable to pass the mixture of fat and powder through a paint mill to insure fineness and smoothness. I. Rotten stone av.oz. 16 Stearin , av.oz. 8 Cottonseed oil fl.oz. 4 Oil of mirbane. . . .enough to flavor Melt the fats, incorporate the rotten stone with them, and add the oil of mirbane when cool. II. Oxalic acid dr. 2 Peroxid of iron (jeweler's rouge) av.oz. 4 Rotten stone av.oz. 5 Palm oil ' av.oz. 15 Petrolatum av.oz. 1 Pulverize the acid finely and add the rouge and rotten stone, mixing thor- oughly. Sift to remove all grit; then gradual^ add the palm oil and petro- latum, and incorporate: Add oil of mirbane or oil of lavender to flavor. III. Crocus martis part 1 Oleic acid sufficient Petrolatum, to make parts 4 Make a paste of the crocus martis with the acid, and then add enough petrolatum to make 4 parts. IV. Tripoli av.oz. 8 Mercurial ointment dr. 2 Petrolatum, enough to form a paste This is said to be especially good for white metal goods as well as for trass. The presence of the mercury makes it more than ordinarily efficient. PUTZ TABLETS. Soap, cut fine or powder, .av.oz. 16 Precipitated chalk av.oz. 2 Jeweler's rouge av.oz. 1 Cream of tartar av.oz. V/ 2 Magnesium carbonate av.oz. 1 Water sufficient Make a paste of the mixture with water and make into tablets which may be dispensed loose or in flat tin boxes. This, like ptirz pomade, is used for polishing purposes. 1152 THE STANDARD FORMULARY PYROTECHNIC PAPERS. See Fireworks Papers. RAT EXTERMINATORS. Various substances are used for ex- terminating or destroying rats and other rodents. These include arsenic, strych- nine, phosphorus, plaster of Paris, bar- ium, squill, etc. The methods of prep- aration are described below : Arsenical Preparations. These may be in the form of a pow- der, paste or pellets. The arsenic need not be the chemically pure arsenous oxid but may be the common powdered arsenic of commerce which is usually known as "white arsenic." Plaster of Paris is added to increase the efficacy of the arsenic and to act as a diluent. Sugar is sometimes added for sweet- ening purposes ; flavoring oils and color- ing substances are also added. I. White arsenic av.oz. 8 Plaster of Paris av.oz. 6 Sugar, powder av.oz. 2 Mix thoroughly. The directions for use may be as fol- lows : Mix the powder with three times its bulk of grease (any kind), butter, cheese, cornmeal, or any food rats or mice will eat. II. White arsenic av.oz. 2 Plaster of Paris av.oz. 8 Flour av.oz. 8 Lampblack gr. 20 Oil of anise drops 5 Mix well and use like the preceding. The lampblack is for coloring purposes only. III. White arsenic ".av.oz. 4 Sugar, powder av.oz. 2 Wheat flour av.oz. 10 Aniline blue gr. 20 Oil of anise drops 30 Mix thoroughly. When this powder is used, it may be moistened with water and made into a dough which may be divided into pel- lets and scattered near the haunts of the rats and mice. Barium Preparations. These have had some recommenda- tion because of their non-poisonous character (to human beings and domes- tic animals). IV. Barium carbonate av.oz. 4 Sugar powder av.oz. 1 Bread av.oz. 16 Mix well, add water, and make into 200 pellets. V. Barium carbonate, precipi- tated av.oz. 10 Ultramarine blue av.oz. 1 Wheat flour av.oz. 3 Star-anise, powder av.oz. 1 Sugar-house syrup and glycerin, enough to make a mass or paste Divide into balls the size of a hazel nut, dust these with flour, and plao. them in the rat holes and along the runways of the rats. These balls may be used with perfect safety in bari-r. — H. RAT SCENTS. (Rat Catcher's Oil.) These preparations are applied to bait and to traps and also used on the hands of professional rat-catchers. I. Oil of rose geranium fl.dr. 1 Oil of cubeb fl.dr. 1 Oil of copaiba fl.dr. 6 II. Oil of anise fl.dr. 2 Nitric acid drops 3 Musk gr. 1 The latter should first be triturated with a small amount of sugar. RAZOR PASTES. (Razor-Strap Pastes.) I. Razor paste can be easily made by taking emery flour and shaking up with water and allowing to stand a moment to allow the coarse particles to subside; then pour off the remainder into a pa- per filter and allow to drain and dry. When dry mix with enough petrolatum or simple ointment to make a paste. II. Emery flour. Jeweler's rouge. Simple ointment, each, equal parts. DOMESTIC UTILITIES. 1153 III. Emery flour av.oz. i Wood charcoal av.oz. I Tin oxid av.oz. i Jeweler's rouge (crocc. martis) av.oz. I Oleic acid fl.dr. 5 Lard av.oz. 2 All the solids must be in the finest powder and the whole must be well mixed. — D. RAZOR PAPER. Slightly dampen, smooth, unsized ca- per and on one surface rub in a mix- ture of finely powdered oxid of iron and emery flour. Then cut into pieces about 3 by 5 inches and dry. These are used to wipe razors after which they do not require stropping. RESINS, BLEACHING. - Resins intended for the production of lacquers and varnishes may be bleached as follows: Resin, cru^e or ordinary, .av.oz. 5 Water, hot fl.oz. 20 Sodium carbonate, crystal. av.oz. 1 Solution of soda, U. S. P. ..fl.oz. 20 Sulfurous acid, gaseous. . .sufficient Add the water to the resin, bring the mixture to a boil, add the sodium car- bonate and solution of soda and con- tinue heating until the resin is dis- solved. Now strain, and into the cola- ture pass gaseous sulfurous acid until the resin is precipitated, collect the lat- ter, wash it with water, and dry at a moderate heat. — H. modified. REDUCING SOLUTION for Photog- raphy. I. The best formula is said to be Biletzki's, made as follows: Sodium hyposulfite av.oz. 5 Potassium ferric oxalate. av.oz. 1 Sodium sulfite av.oz. 1 Oxalic acid, crystal gr. 140 Distilled water fl.oz. 20 Dissolve the ferric salt and sodium sulfite in the water, add the crystal acid to the solution, and shake until the latter changes in color from blood-red to bright green. Decant from any un- dissolved acid, and in this liquid dis- solve the sodium hyposulfite. The negative does not require free- ing from hypo before applying this solution. The liquid keeps well in the dark, does not stain, and may be used over and over again until quite yellow. II. Lumiere's solution : Cerium sulfate av.oz. 1 Sulfuric acid m. 20 Distilled water fl.oz. 10 Mix and dissolve. This may be diluted with from 3 to 6 parts of water, according to the ra- pidity of reduction desired. The solu- tion is said to keep well and may be used repeatedly. RESIN PAPER See Paper, Resin. ROACH EXTERMINATORS. Roaches, also known as cockroaches, are of different kinds or species but their habits are practically alike and the methods of destroying them are the same. They are not easily exterminated readily because they are a very wary insect and besides breed prodigiously. The Department of Agriculture in the Division of Entomology in making its studies in the readiest means for the extermination of roaches observed that fumigation with hydrocyanic acid gas proved very destructive. However, this gas is so very poisonous that its use is not recommended. Burning of insect powder in the infested apartment is also very effective, often destroying the roaches when dusting about of the oow- der proved of no avail. For direct ap- plication, good insect powder is recom- mended; sulfur also proved useful. Other roach exterminators are the following : Liquids. I. Oil of eucalyptus fl.dr. 4 Gasoline fl.oz. 8 Oil of turpentine fl.oz. 8 Kerosene, to make fl.oz. 64' The author of this formula recom- mends taking small bits of banana or banana peeling, soaking them in this liquid, and laying them around at nigth 1 1 54 THE STANDARD FORMULARY in places frequented bv the roaches. Some are killed by eating the bananas and others are driven out. Pastes. Many of the roach pastes are "phos- phorus pastes," or so-called "electric pastes." See formulas under Phos- phorus Pastes. Others are made with red lead or other ingredients. These pastes may be distributed on papers in fhe haunting places of the roaches, or they may be fed into cracks or crevices in which the insects hide. II. Red lead av.oz. 4 Flour av.oz. 12 Molasses to make a soft paste III. Red lead av.oz. 4 Corn meal, powder av.oz. 8 Molasses to form a soft paste IV. Insect powder av.oz. 8 Borax, powder av.oz. 8 Quicklime av.oz. 4 Oil of eucalyptus fl.dr. j. Mix well. The lime may be replaced by sulfur. V. Insect powder av.oz. 3 Borax, powder av.oz. 16 Red precipitate gr. 2 Cudbear gr. 2 Carmine gr. 2 VI. Borax, powder. Insect powder. Colocynth, powder, each, equal parts. VII. Insect powder av.oz. 24 Boric acid av.oz. 5 Sugar av.oz. 2 Oil of cedar fl.dr. 2 RUBBER GOODS, To Preserve. As a result of extended investiga- tions by the Russian Army Medical Committee in 1893 it was determined that the best medium for preserving caoutchouc articles, hard or soft, is a 3% carbolic acid solution, such articles keeping for as long a pe- riod as ten years without change. The next best was a $% solution of aniline. but this lias certain manifest disad- vantages. Lime water, which was strongly recommended, failed in many respects. The solution required fre- quent changing, a deposit of calcium carbonate formed on the immersed ob- jects, mold often developed, and the elasticity of the rubber suffered. In a solution containing 8% of glycerin and the same proportion of alcohol new rubber may be kept fairly well, but de- teriorated tubing recovered none of its original elasticity. A 1% pentasulfld of potassium solution has the special virtue of restoring to hardened rubber some of its former properties, but the offensive odor of the solution would prevent its general employment. The carbolic solution is the most convenient and effective; its antiseptic action, too, is a strong point in its favor for hos- pital use. RUBBER PIANO COVERS, To Clean. Spread the covers on any convenient object, and scoured with water, using a liquid soap made of spirit of soap, yolk of eggs and oil of turpentine, after the following formula : Spirit of soap fl.oz. 5 Oil of turpentine fl.oz. 1 Yolk of eggs No. 5 This is rubbed on the cover with a sponge, warm water is then applied, and the surface scrubbed with a stiff brush. For badly spotted or stained covers, the following is recommended : Ox-gall fl.oz. 8 Alum, powder fl.oz. 1 Table salt fl.oz. 1 Mix and boil together for a few min- utes. After cooling, bottle for use. A little essential oil of lavender or lemon may be added to cover the nauseous odor of bile. This may be used in the same manner as the foregoing prepara- tion. RUBBER-STAMP INKS. See Inks, Stamping. RUST STAIN Removers. The following are recommended: I. Tartaric acid av.oz. 1 DOMESTIC UTILITIES. 1155 Alum av.oz. I Water, to make fl.oz. 16 Mix, dissolve and filter. II. A mixture of 2 parts of pow- dered cream of tartar with 1 part of powdered oxalic acid will remove stains from cotton and linen. Dampen the goods, apply the powder, allow to remain for a short time, and rinse in clear water. This mixture is said to work better than oxalic acid alone. III. Rust Stains on White Goods. — Soak the stains in a solution of tin chlorid, and rinse immediately with much water. The tin salt is much more reliable in removing iron rust, and quicker in its action than oxalic acid, unless the stains are soaked in a solu- tion of the latter, contained in a tin spoon, when the stains disappear in a short time. SAFETY PAINT. See Fireproofing Fabrics, Wood, etc. SCALE PANS, To Clean. Nickel or silvered pans may be cleaned with whiting and ammonia. To clean brass scale pans, pour suf- ficient ammonia in the pan to cover the bottom, and rub briskly till dry with a handful of dry pine sawdust. For very dirty pans, take about a dram of potassium bichromate, powder it in a mortar, mix it with two or three times its bulk of concentrated sulfuric acid, and add twice as much water. With this rub the pans (having a care for the fingers), rinse well, and polish with a cloth moistened with oil and precipitated chalk or rotten stone. SALT OF LEMON, Artificial. The following formulas have been given : I. Oxalic acid av.oz. 4 Potassium carbonate av.oz. 2 Cream of tartar av.oz. 6 II. r Oxalic acid av.oz. 6 Cream of tartar av.oz. 8 73 SCENTS for Attracting Animals. I. For catching destructive butterflies : Fly lime av.oz. 4 Honey av.oz. % Apple ether drops 40 Cumarin gr. 1 Mix by the aid of a gentle heat. Smear the above on sticks of wood and set these in the garden which is to be protected. The butterflies will be caught on the sticky wood and will die there.— D. II. For catching butterflies for a cabinet : Common honey av.oz. 10 Cumarin sugar . > gr. 45 Apple ether fl.dr. Lj4 Mix by the aid of a gentle heat. Smear this mixture on thick woolen yarn, and, towards evening, wind the latter in and about the bush tops. Then upon going out after dark — at intervals of about one hour — with a bright lan- tern or other bright light, the butter- flies will be blinded and may be cap- tured easily with the hand. — D. III. For catching crayfish : Rancid tallow av.oz. 7 Cod liver oil fl.oz. 2 Oil of spike fl.oz. 1 Mix by the aid of heat. Anoint the dry net with this mixture which may also be applied to the bait. — D. IV. A. For foxes : Tincture of musk fl.oz. 1 Olive oil fl.oz. 10 — H. B. Civet gr. 15 Camphor gr. 60 Asaf etida gr. 120 Orris root gr. 180 Valerian gr. 180 Fennel av.oz. s J A Oil of anise drops 15 Mix and reduce to powder. — H. V. For wild animals : Musk gr. 5 Civet gr. 3 Castoreum, Canadian gr. 45 Oil of cascarilla drops 5 Oil of valerian drops 5 Oil of angelica drops 5 Oil of patchouli drops 5 Starch av.oz. ^Vx 1156 THE STANDARD FORMULARY Mix well and oreserve in a well-stop- pered bottle. — D. VI. For rabbits: Use a mixture of oils of anise, cara- way, and rhodium. VII. See also Rat Scents. SEA SALT, Artificial. (Sal Mari- num.) Various formulas are given : I. Sodium chlorid av.oz. 80 Magnesium chlorid av.oz. 11 Megnesium sulfate av.oz. 6 l / 2 Calcium chlorid av.oz. 2 Potassium bromid gr. 130 Potassium iodid gr. 90 — D. II. Sodium chlorid av.oz. 80 Magnesium sulfate av.oz. 16 Calcium chlorid av.oz. 3 l / 2 Potassium iodid gr. 70 Potassium bromid gr. 35 • — H. III. Sodium chlorid av.oz. 78 Magnesium chlorid av.oz. 11 Potassium chlorid av.oz. 3 Calcium sulfate av.oz. 3 Of the dry mixture 1 av. pound is to be dissolved in 30 pints to make arti- ficial sea water for aquaria. SEA WATER, Artificial. See under Sea Salt, Artificial. SEALING WAXES. These consist of resinous substances in combination with coloring agents, the mixture frequently being cheapened by the addition of mineral substances. In preparing these, the less fusible resins, such as rosin and shellac should be melted, then the turpentine, Venice tur- pentine or similar more fusible a^ent should be added, and with this mixture should be incorporated the remaining ingredients. The powdery substances should be added in the very finely di- vided form, and should be added last; if there are several powders, they should be well mixed before adding to the liquefied resins. When the ingredients have been mixed, the heating should be continued for a few moments to per- mit the escapt of air bubbles which have been introduced during mixing of the ingredients. The mixture may be cast into sticks, if desired, by pouring into suitable molds which have previously been an- ointed with petrolatum. To cool off to the consistency re- quired for molding, pour off about one- sixth of the mixture on a piece of wetted parchment paper, and as soon as this mass has hardened it should be re- turned to the vessel and stirred until the cooled portion is dissolved; the mixture may be poured into the molds. A good general formula for sealing wax is this : I. Rosin av.oz. 8 Shellac av.oz. 4 Venice turpentine av.oz. 3 Mix by melting; then add the color- ing matter, lampblack, ultramarine blue, Paris green, umber, Armenian bole, red lead, Venetian red, bone black, etc. II. A softer wax may be made ac- cording to this formula: Rosin av.oz. 8 Yellow wax av.oz. 8 Olive oil av.oz. 5 Venice turpentine av.oz. 12 Color like the ^receding. Black Sealing Wax. Bone black may be used instead of lampblack for coloring the mixture. III. Shellac av.oz. 12 Venice turpentine av.oz. 8 Resin av.oz. 1^2 Lampblack sufficient to color IV. Resin av.oz. 10^2 Gum turpentine av.oz. 2% Stearin av.oz. 1 Lampblack gr. 40 Heavy spar (barium sul- fate) av.oz. 20 — D. V. Resin av.oz. 10 Chalk av.oz. 2^2 Lampblack s av.oz. 1 Venice turpentine av.oz. Yz Melt the resin, add the Venice tur- DOMESTIC UTILITIES. 1157 pentine and incorporate with the chalk and lampblack which have previously been well mixed. Blue Sealing Wax. VI. White shellac av.oz. 7 Venice turpentine av.oz. 3 Resin av.oz. 1 Prussian blue av.oz. 1 Calcined magnesia gr. 90 VII. Resin, white av.oz. 15 Gum turpentine av.oz. 4 Ultramarine blue av.oz. 2 Heavy spar (barium sul- fate) av.oz. 2.y 2 VIII. Resin, white av.oz. 15 Gum turpentine av.oz. 4 Ultramarine blue av.oz. 2 Zinc oxid av.oz. 2 Heavy spar (barium sul- fate) av.oz. 2.y 2 — D. Green Sealing Wax. IX. Resin av.oz. 10 Venice turpentine av.oz. \y 2 Chalk av.oz. 2^ Chrome green av.oz. 1 Melt the resin, add the turpentine, and then incorporate the chalk and chrome green which have previously been well mixed. X. Shellac av.oz. 8 Mastic av.oz. 4 Gum turpentine av.oz. i l / 2 Verdigris av.oz. 2 XL Paris green may also be em- ployed as the coloring agent. Bed Sealing Wax. The coloring agents used may be vermilion or red lead, or even Venetian red. XII. Shellac, bleached av.oz. 8 Venice turpentine av.oz. 5 Chinese vermilion two papers XIII. Shellac av.oz. 10 Venice turpentine av.oz. 2 Vermilion av.oz. 4 Bleached shellac should be used in making this wax. Violet Sealing Wax. XIV. Resin, white , . . av.oz. yy 2 Gum turpentine av.oz. 2 Carmine av.oz. y 2 7ax\q. oxid av.oz. 2 Ultramarine blue dr. 2 Heavy spar (barium sul- fate) av.oz. 10 — D. White Sealing Wax. XV. Bleached shellac av.oz. 7 Venice turpentine av.oz. 3% Plaster of Paris av.oz. 2 Bismuth subnitrate av.oz. 3 Lead carbonate av.oz. 4^2 Magnesia dr. 2 XVI. Resin, white av.oz. 7^ Gum turpentine av.oz. 2 Zinc white av.oz. 2 Lleavy spar (barium sul- fate) av.oz. &y 2 — D. Yellow Sealing Wax. XVII. Shellac, bleached av.oz. 8 Resin av.oz. 2^ Venice turpentine av.oz. 4 King's yellow (sulfid of arsenic) av.oz. i i y 2 SEWING MACHINE OIL. Sp:rm oil has been used as a sewing machine oil but it is considered too heavy for this purpose and should be thinned with some kerosene. Most sewing machine oils of the present time are the lighter paraffin oils. A patented preparation (1872) was directed to be made from a mixture of 3 gallons of sperm oil, 2 quarts of crude petroleum oil, 1 quart "spirit" of turpentine, and y 2 pound of oil of wintergreen, this to be drained through woolen cloths spread over with powdered charcoal. SHELLAC SOLUTION, To Make Clear Alcoholic. The milky appearance of alcoholic solution of shellac is due to the pres- ence of a waxy matter in the shellac which is insoluble in alcohol, and mav be separated by shaking the alcoholic solution with benzine, which dissolves the wax, and after the liquids- separate 1158 THE STANDARD FORMULARY pouring off the upper layer. An alco- hol of about 85^0 should be used. An- other method is to triturate with mag- nesia, precipitated chalk or some other finely divided insoluble substance and filtering. This effects the separation me- chanically, but is objectionable on ac- count of the loss of liquid absorbed by the powder. SHELLAC, Bleaching of. See Bleached Shellac. SHOE BLACKING, LIQUID. (La- dies' Shoe Dressing.) These preparations are usually resin- ous solutions colored black, and in- tended for application to shoes by means of sponge. They dry quickly, and give a polish without friction with a brush. Whenever bone or ivory black is di- rected in a formula, the purified arti- cle should be preferred, as it gives a dead-black color; whereas the unpuri- fied may give but a brownish or gray- ish black. All the formulas mentioned herein come well recommended. I. Borax av.oz. 2 Shellac, powder av.oz. 6 Water fl.oz. 4)0 Dissolve the shellac in the borax and water by heating on a water bath, stir- ring frequently. This will require sev- eral hours. Then add nigrosine suffi- cient to color. Water must be added from time to time to make up for that lost by evaporation. Other colored dressings may be ob- tained by adding other dyes; for red, use eosin or fuchsin; for blue, methyl blue • green, malachite or methyl green ; violet, methyl violet; etc. II. Bleached shellac av.oz. 4 av.oz. 2 av.oz. 4 av.oz. 2 av.oz. 1 Water sufficient Mix the shellac, borax, and 14 fluid- Borax Sugar . Glycerin Nigrosin ounces of water, and heat with constant stirring until the shellac is dissolved ; then add the sugar, glycerin and nigrosin ; stir until the latter is dissolved, and add enough water to make 36 fluidounces. — D. SHOE BLACKING, Paste Form. There are a variety of formulas here given and as may be observed they are mostly of a crude and unscientific as- pect. They are however, the best that are available and most of them are well vouched for. There are two kinds of blacking, the older kind, made with sulfuric acid, and the more modern, acid-free kind which is suitable for pat- ent leather and the finer grades of shoes. The gist of the former kinds is that the calcium phosphate is decomposed by the strong sulfuric acid, calcium sul- fate and acid phosphate being formed, a uniform mixture being thus obtained. Oil and saccharine substances, if pres- ent, are at the same time partially car- bonized by the acid, thereby assisting to make an intimate combination. Acid Blackings. I. Brunner's Shoe Blacking : Bone black av.oz. 10 Syrupy glucose av.oz. 10 Train oil av.oz. 20 Sulfuric acid av.oz. 5 Water fl.oz. 4 Sodium carbonate av.oz. 2 In a porcelain vessel mix the bone black and glucose, then rapidly and evenly stir in the acid. This is the most imoortant part of the proceedings, for, if improperly done, the mass will be granular. When the mixture has ac- quired a shining black surface, when at rest, set aside. Dissolve the soda in the water, add to the oil, and boil, under constant stirring, until a thick mass is formed. Then stir into this the first mixture. What are known as "French"' polishes are based on this process, various degrees of hardness being obtained by altering the propor- tions, using stale beer for thinning. DOMESTIC II. Liebig's formula : Ivory black av.oz. 8 Molasses av.oz. 4 Sweet oil av.oz. 1 Hydrochloric acid, com- mercial av.oz. 4 Sulfuric acid, commercial, .av.oz. 4 Water sufficient Mix the ivory black with the mo- lasses and oil, add the hydrochloric and sulfuric acids, first mixing the latter with 3 or 4 fluidounces of water, and adding while hot. Let stand until all effervescence ceases, stirring occasion- ally, and finally, thin to the desired con- sistence with stale beer. III. Ivory black av.oz. 12 Molasses av.oz. 6 Olive oil fl.dr. d Balsam of copaiba fl.dr. 2 Sulfuric acid av.oz. 1 Vinegar, to make a paste of suitable consistence. Mix the oil and balsam with the ivory black, add the acid to the molasses, and mix this with the preceding. Allow to stand for 2 or 3 days, then add enough vinegar. IV. This is said to be Day & Mar- tin's formula as given by Mr. Day him- self : Ivory black av.oz. 16 Lampblack av.oz. 16 Molasses av.oz. 16 Sperm oil fl.oz. 4 Vinegar fl.oz. 5 Sulfuric acid oz. 4 Iron sulfate av.oz. x / 2 Gum arabic av.oz. Y\ Water, hot fl.oz. 5 Mix the first five ingredients, then add gradually the sulfuric acid, stirring in well. When the reaction ceases, add the iron sulfate and gum dissolved in the water. Beat well in a mortar or pass through a mill until the paste is of good consistency. Acid-Free Blackings. V. Yellow wax, or ceresin. . .av.oz. 3 Spermaceti av.oz. 1 Oil of turpentine fl.oz. 11 Asphalt varnish av.oz. 1 UTILITIES. 1159 Frankfort black av.oz. 1 Borax, powder gr. 80 Prussian blue gr. 150 Oil of mirbane fl.dr. V/ 2 Melt the wax, add the borax, and stir until a kind of jelly has been formed. In another pan melt the spermaceti ; add the varnish, previously mixed with the turpentine; stir well and add to the wax ; lastly, add the colors, mix well, and incorporate the oil of mirbane. VI. Carnauba wax av.oz. 8 Sperm oil fl.oz. 4 Oil of turpentine fl.oz. 12 Soap, powder av.oz. 1 Oil of mirbane fl.dr. 1 Melt the wax and sperm oil together in a water-bath, remove from the source of heat, and add the oil of turpentine. When mixed, add the soap and oil of mirbane, and make into a homogeneous paste by trituration in hot mortar. SHOE DRESSING, Tan or Russett. These consist of a cleaner and a polisher, the former being a liquid, the latter a paste. The Cleaning Fluid. I. Tragacanth dr. 2 Oxalic acid dr. 3 Water fl.oz. 32 Mix and dissolve. It should be col- ored yellowish with aniline yellow or saffron. II. Yellow wax av.oz. 4 Linseed oil, raw fl.oz. 6 Oil of turpentine fl.oz. 20 Soap av.oz. .2 l / 2 Water, hot fl.oz. 28 Melt the wax at a gentle heat, then cautiously incorporate the two oils. The soap, which may be the ordinary yellow bar, should be in shavings and should then be dissolved in the water. Now mix the two liquids. The Polish. III. Petrolatum, yellow av.oz. 24 Yellow wax av.oz. 8 Mix by fusion. 11 GO THE STANDARD FORMULARY . .av.oz. i . .av.oz. 8 . .av.oz. 24 IV. Rosin Yellow wax Petrolatum Mix by fusion. V. Yellow wax av.oz. 16 Palm oil av.oz. 8 Oil of turpentine fl.oz. 16 Prepare like the preceding. SHOE DRESSING, White. These are intended as dressings for white canvass shoes. Some are made with a borax-shellac body, others are resinous in character, the resin being dissolved in alcohol. I. Shellac, white av.oz. 2 Borax av.oz. 6 Water fl.oz. 32 Pipe clay or chalk sufficient Dissolve the shellac in the borax water by the aid of heat, adding water from time to time to make up for that lost by evaporation, then add the pipe clay or chalk in sufficient quantity. By using less w r ater and adding a little soap, a paste preparation may be obtained. II. Shellac, bleached ....av.oz. 2 Borax av.oz. 6 Sugar av.oz. 4 Glycerin fl.oz. 2 Zinc oxid av.oz. 4 Pipe clay av.oz. 8 Water fl.oz. 20 Prepare like Xo. I. III. Pipe clay av.oz. 16 Whiting av.oz. 8 Flake white av.oz. 6 Precipitated chalk av.oz. 4 Tragacanth, powder dr. 2 Carbolic acid dr. 2 Water, enough to make a thick paste or cream. This is a modification of a formula said to be used in India. IV. Sandarac av.oz. 5 Rosin av.oz. 4 Burgundy pitch av.oz. 2 White shellac av.oz. 1 Alcohol fl.oz. 36 Pipe clay sufficient Dissolve the first four ingredients in the alcohol, strain, then add a suf- ficient quantity of pipe clay. SHOE-FINISHER'S INK. (Burnish- ing Ink.) Shoe-finisher's ink or "burnishing" ink is the liquid applied to shoe leather to change it to a black tint. It is ap- plied to the edges of new soles. I. Standage's formula : Logwood extract av.oz. 3 Xitric acid m. 45 Ferrous sulfate crystals Water, each sufficient Boil the extract in a porcelain vessel with 16 fluidounces of water until the extract is dissolved, cover with paper to exclude dust, and set aside for 2 weeks. Now into a glass-stoppered bottle, put 3 drams of iron sulfate, add just enough water to dissolve the latter, and then the acid, and close the bottle. Mix the ingredients well and then add iron sulfate little by little until no more can be dissolved. Allow this mixture to stand a few hours and decant the clear liquid. To the logwood extract solution add from 2^ to 5% of the iron solution. Stir for 5 or 10 min- | utes when the mixture becomes of a purple hue as will be seen by observ- ing it at the edges. If too much iron is added, the ink assumes a reddish hue. This formula is the result of chemical investigation and should be an excel- lent one. SHOE GREASE. See also under the similar heading Harness Dressing and Oil. I. Petrolatum av.oz. 2 Olive oil, common fl.oz. 2 Ceresin av.oz. 5 Alkannin gr. 10 ' Oil of mirbane drops 6 Oil of citronella drops 3 Melt the ceresin, add the petrolatum, oil and alkannin ; allow to cool, and incorporate the oils of mirbane and citronella. DOMESTIC UTILITIES. 1161 II. Yellow wax av.oz. I Gum turpentine av.oz. I Castor oil av.oz. I Linseed oil fl.oz. 10 Pine tar dr. 2 Clean the leather; let dry, and rub the grease well in before a fire. III. Resin av.oz. 2 Yellow wax av.oz. 3 Linseed oil fl.oz. 12 Xeatsfoot oil fl.oz. 8 Oil of turpentine fl.oz. 4' This has been known as Norfolk fluid. IV. Paraffin oil, yellow av.oz. 28 Olive oil, common av.oz. 2 Ceresin, yellow av.oz. 10 Alkannin gr. 18 Oil of mirbane drops 12 Oil of citronella drops 6 Melt the ceresin and acid the other ingredients, dissolving the alkannin by agitation in the warm fat. — D. The alkannin may be omitted and other scents may be used. V. Beef tallow av.oz. 16 Yellow wax Burgundy pitch Petrolatum Castor oil Oil of citronella av.oz. 6 av.oz. 4 av.oz. 8 .fl.oz. 48 .fl.dr. 4 Melt the first three ingredients to- gether, then incorporate the petrolatum and neatsfoot oil, and, when cooled, add the citronella oil. SHOE AND HARNESS MAKERS' WAX. I. Yellow: ' Burgundy pitch, yellow wax, equal parts of each. Mix by fusion. — D II. Black: Burgundy pitch av.oz. 5 Yellow wax av.oz. 4M2 Lampblack gr. 45 Linseed oil, raw fl.dr. 2^2 Make a smooth mixture of the lamp- black and oil, then incorporate with the wax and pitch which have previ- ously been melted together.— D. SHOE POLISHES, Patent Leather. These are the acid-free blackings mentioned under Shoe Blackings, Paste Form. SHOES, TAN, Blackening of. Before using any of these stains, the shoes should be thoroughly cleansed with soap and water and then dried so as to remove all dirt as well as fatty matter remaining from polishes. The preparations mentioned under Shoe-Finisher's Ink will also serve for this purpose. I. Extract of logwood av.oz. 2 Tincture of ferric chlorid. .fl.oz. 4 Tannin , dr. d Alcohol, to make fl.oz. 16 Shake all together till nearly dis- solved. In using apply with a sponge or camel- hair brush, let dry for 12 hours, then rub with a soft rag and apply the stain again. When dry polish with a soft shoe brush or woolen rag. Polish after- wards in the usual manner with shoe blacking. II. Extract of logwood av.oz. 2 Ferrous sulfate dr. 1 Potassium bichromate gr. 30 Water fl.oz. 16 Mix and dissolve by agitation or the application of heat. SHOE VARNISH, Patent Leather. I. Shellac av.oz. 3% Gum turpentine av.oz. i}4 Sandarac dr. 4 Lampblack dr. 2 Oil of turpentine fl.dr. 10 Alcohol . . ". fl.oz. 30 Dissolve the three gums in the alco- hol, strain, and then add the oil and lampblack so as to make an intimate mixture. SHOES, Waterproofing for. The following is recommended: Linseed oil, raw fl.oz. 8 Mutton suet av.oz. 4 Yellow wax av.oz. 4 Rosin av.oz. l / 2 1162 THE STANDARD FORMULARY Melt the rosin, wax and suet and incorporate the oil. Apply the mixture at a temperature of about I40°F., preferably using a brush. On the first application give two coats, being careful to get the preparation well into the seams around the soles, etc. For subsequent applications one coat (applied quite hot) will be suffi- cient. This is also recommended: Make a 10 or 15% solution of glue or gelatin in water with about 1% of glycerin, and add also a 10% solution of potassium bichromate. The bichrom- ate solution is to be added only when the liquid is needed. Apply this in the dark, with a brush, and then expose the shoes or boots to direct sunlight for an hour or two. SHOW GLOBE COLORS. Colored liquids for show globes, show globe colors as they are termed, are frequently made of coal tar dyes, and very handsome colors may be pro- duced in this way, but these, as a rule, lack permanency. However, these col- ors are inexpensive ; so very little of the dye being required that they may be "freshened" occasionally, or they may be entirely renewed. Those who do not care to use coal tar dyes may employ the formulas mentioned below. It should be understood, however, that no show bottle colors are absolutely permanent, because they are exposed to one of the most powerful of all chemical agents, viz., light. From time to time they should be filtered or else renewed, and the bottle should be thor- oughly cleansed. Show bottle colors are liable to be subjected to considerable cold in winter time and to be frozen. This may be prevented by replacing 20 or 2s9c of the water with alcohol or glycerin. Such replacement cannot always be made, owing to possible chemical change — for example, in purple made with potassium permanganate. The colors most commonly employed are red, green, blue and yellow. The formulas given below will yield these colors in several different shades. These shades may in each instance be made lighter or darker by increasing or de- creasing the proportion of water. The usual fault in making show-globe colors is that they are too dark. They should always be quite light as then they are more brilliant and lights placed behind them will show to much greater advantage. All the solutions must be filtered un- til they are absolutely clear and bright. Amber Color. I. Dragon's blood gr. 45 Sulfuric acid fl.dr. 3 Distilled water gall. 2 Powder the dragon's blood and mac- erate in the acid for 20 or 30 minutes, then add the distilled water and filter. II. Potassium bichromate av.oz. 8 Nitric acid fl.oz. 16 Water, to make gall. 2 Dissolve the bichromate in the water, add the acid, and filter. Alcohol or glycerin must not be added to this liquid. Amethyst Color. III. Sodium salicylate gr. 10 Tincture of ferric chlorid. . . .m. 30 Water gall. 2 Dissolve the salicylate in the water, and add the tincture. Blue Color. Different shades of blue are produced by these formulas. Copper nitrate may take the place of copper sulfate. IV. Copper sulfate av.oz. 16 Sulfuric acid fl.oz. 2 Water gall. 2 V. Copper sulfate gr. 240 Ammonia water sufficient, or fl.oz. 1 to 2 Water gall. 2 Dissolve the copper salt in water, add DOMESTIC UTILITIES. 1163 ammonia water until the precipitate first formed is redissolved, and add the remainder of the water. VI. Dissolve Prussian blue in water by the aid of oxalic acid, or dissolve soluble blue or indigo sulfate in water. VII. Copper sulfate av.oz. 8 Alum av.oz. 8 Sulfuric acid fl.oz. 8 Distilled water gall. 2 Dissolve the alum and copper sulfate in the water, cautiously add the sul- furic acid, and filter. Canary Color. VIII. This is a light shade of yellow, which see. Crimson Color. IX. Solution of iron chlorid fl.oz. i^ Ammonia water fl.oz. i Acetic acid fl.oz. 2 Alcohol fl.oz. 6 Distilled water gall. 2 Add the solution of iron chlorid to the water; then add the alcohol, acetic acid and ammonia water, and filter. X. Iodin av.oz. l / 2 Potassium iodid fl.oz. Yz Hydrochloric acid fl.oz. g Distilled water gall. 2 Dissolve the iodin and potassium iodid in the water ; add the hydrochloric acid, and filter. XI. Alkanet root av.lb. 2 Oil of turpentine gall. 2 Percolate the drug, previously finely ground, with the oil. This makes a bright, beautiful color. If the show jar should be broken, there would be considerable danger of fire if there were any lights or fire near- by. Garnet Color. XII. Potassium bichromate av.oz. 16 . Sulfuric acid fl.oz. 16 Water gall. 2 Dissolve the bichromate in the water and add the acid gradually with 'stir- ring. Clarify by allowing to stand and decant the clear portion. Green Colors These formulas produce different shades of green, such as emerald green, grass green, sea green, olive green, etc. Some of the colors are made with cop- per salts as a basis, others with nickel salts. The latter furnish the lighter colors. XIII. Copper sulfate av.oz. 27 Hydrochloric acid fl.oz. 24 Distilled water gall. 2 Dissolve the copper sulfate in the distilled water, and the hydrochloric acid and filter. XIV. Verdigris av.oz. 24 Sulfuric acid sufficient Distilled water gall. 2 Mix the verdigris with enough acid to dissolve ; let stand a few minutes, add to the distilled water and filter. XV. Copper sulfate av.oz. 9 Ammonium chlorid av.oz. 9 Water, to make gall. 2 First dissolve the copper salt in the water, then add the ammonium chlorid; dissolve and filter. XVI. Copper acetate av.oz. i J /£ Acetic acid fl.oz. 11 Water, to make gall. 2 Add the acetic acid to the copper acetate, and triturate with the water till dissolved. XVII. Add an aqueous solution of picric acid to an aqueous solution of copper sulfate until the desired shade is produced. A beautiful grass green liquid will be the result. A variation of this may be obtained by dissolving copper sulfate in water, adding ammonia water till the precipi- tate first formed is redissolved, then adding the picric acid solution. Both solutions must be used very dilute. XVIII. Copper sulfate av.oz. 8 11G-A THE STANDARD FORMULARY Nitric acid fl.oz. 12 Water gall. 2 Dissolve the copper salt in the water, add the acid, and filter through glass wool. This has a bluish-green color by re- flected light or daylight and clear green by transmitted light. Lemon or Straw Color. XIX. Potassium bichromate av.oz. 2 Sodium bicarbonate av.oz. iy 2 Water, to make gall. 2 Dissolve the bichromate in a small amount of water, then add the bicar- bonate. When effervescence ceases, add the remainder of the water, and filter. 10% of alcohol may be added if desired. Magenta Color. XX. Chromic acid dr. 1 Muriatic acid fl.oz. 2 Nitric acid fl.oz. 2 Water gall. 2 Mix, dissolve, and clarify either by filtration or by subsidence and decanta- tion. Orange Color. XXI. Dissolve annatto in solution of potassa and dilute alcohol, and filter. Pink Color. XXII. Sodium salicylate gr. 16 Tincture of iron chlorid. Hydrochloric acid, each. . .sufficient Water gall. 2 Dissolve the sodium salicylate in the water and add cautiously tincture of iron in single drops until the proper tint has been realized. Hydrochloric acid may be used carefully (in drops) to render the tint paler. Should too much acid have been added, restore the tint by the addition of ammonia water. Purple Color. XXIII. Verdigris av.oz. 3 Ammonia water fl.oz. 18 Distilled water . . .*. gall. 2 Mix the water and the ammonia, add the verdigris, and, when dissolved, filter. Purple (Brilliant) Color. XXIV. Copper sulfate dr. 2 French gelatin dr. 1 Solution of potassa fl.oz. 32 Water sufficient Dissolve the copper salt in 2 fluid- ounces of water, and the gelatin in the same amount of boiling water; mix the two solutions, add the solution of po- tassa, shake the mixture, let stand 10 hours, decant the cleat liquid, and dilute as desired with water. Red Color. A variety of tints will be obtained by means of these formulas : XXV. Dissolve carmine in ammonia water or liquor potassa, and reduce with water to the desired tint. XXVI. To water in which red cab- bage has been boiled, add sulfuric acid to bring out the color, dilute with water to the desired tint, and filter. XXVII. Cochineal av.oz. i l / 2 Potassium bitartrate av.oz. 1 Sulfuric acid fl.oz. 5 Distilled water gall. 2 Boil the cochineal and potassium bi- tartrate in water until exhausted ; allow to cool, add the sulfuric acid, and filter. Instead of this, the solution of coch- ineal (cochineal coloring) of the Na- tional Formulary may be used. Violet Color. XXVIII. Cudbear av.oz. 2 Ammonia water fl.oz. 8 Water gall. 2 Macerate together fcr 24 hours, and filter. Yellow Color. XXIX. Potassium bichromate av.oz. 10 Nitric acid fl.oz. 20 Distilled water gall. 2 Dissolve the potassium bichromate in the water, and add the nitric acid ; filter. A Fluorescent Color. XXX. Fluorescein (or uranine) . . . .gr. 10 Alcohol fl.oz. 1 Water gall. 2 DOMESTIC UTILITIES. 1165 Dissolve the fluorescein in the alcohol and add to the water. The addition of a small amount of ammonia water or solution of soda increases the fluores- cence. As it is liable to become decomposed, it is advised to pour about 20 or 30 drops' of formaldehyde on the surface of the liquid after it has been filtered into the show bottle. SILVER NITRATE STAINS, To Re- move. The preparations mentioned for re- moving silver nitrate are equally effica- cious against indelible (marking) ink stains, the latter usually having a silver salt as the basis. The following may be tried: (1) First soak in a solution of common salt, and afterward wash with ammonia; (2) Treat with a solution of potassium cy- anid, 10 grains ; iodin, 5 grains, in one fluidounce of water; (3) Moisten with a solution of iodin in potassium iodid, and afterward wash with water ; (4) Treat with a strong solution of zinc sulfate, and then touch with a piece of metallic zinc, afterward washing; (5) Treat with a solution of chlorinated lime (either Javelle water or Labar- raque's solution) ; (6) alizarine ink stains may be removed by treating with a solution of tartaric acid, the older the stain the more concentrated the solu- tion. The following are recommended for removing silver stains from the skin : (1) Potassium cyanid in strong aque- ous solution, but it is so very poisonous that it must be used with extreme cau- tion; (2) A mixture of potassium fer- ricyanid and sodium hyposulfite. A few crystals of the former are dissolved in a solution of hyposulfite, or from 10 to 20% solution of the ferricyanid may be added to the hyposulfite solution and applied to the stains; (3) Dip the fin- gers into a strong solution of copper chlorid. In about a minute the silver will be converted into chlorid and may then be washed off with a solution of sodium hypophosphite. SILVER, To Remove Mercurial Stains from. First apply tincture of iodin, then a concentrated solution of potassium iodid. SILVER, "Oxidizing" of The so-called "oxidizing" of silver is really a sulfuration or the formation of a superficial layer of sulfid. One process is to immerse the silver in a solution of 40 grains of sulfurated po- tassa and 80 grains of ammonium car- bonate in 16 fluidounces of distilled water warmed to 8o° C. Another process is this : To a cup of hot water add about 10 grains of sulfurated potassa, and dissolve. Into this dip the article to be "oxidized," after first making it as white as possible with the scratch brush, and allow it to remain for about 2 minutes. Then take it out, rinse off with clear water, polish again with a scratch brush, and again immerse in the solution. Re- peat this rubbing with a scratch brush and dipping in the solution by which time the article will probably be suffi- ciently "oxidized." SILVER PLATING. See Plating with Gold, Silver, Tin, etc. SILVER POLISH. See under Polishing Powders, or use one of the following : Powders. Cream of tartar av.oz. 2 Prepared chalk av.oz. 2 Alum, fine powder av.oz. 1 When required for use wet sufficient of the powder and with soft linen rags rub the article, being careful not to use much pressure, as otherwise the thin layer of plating may be cut through. Rinse in hot suds, afterward in clear water, and dry in sawdust. When badly blackened with silver sulfid, i'f small, the article may be dipped for 1166 THE STANDARD FORMULARY an instant in hydrochloric acid and im- mediately rinsed in running water. II. Rouge (crocus martis) dr. 2 Magnesium carbonate, heavy av.oz. 4 Precipitated chalk av.oz. 8 Triturate the rouge thoroughly with the other ingredients, then pass the whole through a fine sieve. III. Jeweler's rouge (crocus martis) av.oz. 1 Tripoli av.oz. 1 Sodium hyposulfite av.oz. 2 Prepared chalk av.oz. 8 Make into a very fine powder and pass through a fine sieve. This is to be used like Xo. I. IV. Infusorial earth, which may be bought quite cheaply, makes an excel- lent polish for jewelry and silver- ware. V. Liquids. Prepared chalk av.oz. 3 Ammonia water fl.oz. 3 Alcohol fl-oz. 5 Water , fl.oz. 20 VI. Sodium hyposulfite av.oz. 1 Prepared chalk av.oz. 1 Water fl.oz. 8 Dissolve the hyposulfite in the water, and add the chalk. VII. An excellent polish in liquid form may be obtained by mixing half an ounce of infusorial earth with 3 fluidounces of water. Paste. VIII. Prepared chalk av.oz. 2 Oleic acid fl.oz. 2 Stearin av.oz. 6 Make a smooth mixture of the chalk and acid, then incorporate with the stearin which has previously been melt- ed at a gentle heat. — H. Soap. IX. Jeweler's rouge part 1 Magnesia parts 9 Soap parts 40 Water sufficient Dissolve the soap in the smallest pos- sible amount of hot water by the aid of heat, and incorporate the other in- gredients. SILVER, To Prevent the Tarnishing of. The blackening which silver and sil- ver-plated articles speedily suffer is due principally to the formation of a super- ficial film of silver sulfid by the action of the hydrogen sulfid in the atmo- sphere, especially in cities, where the large consumption of coal and coal-gas charges the atmosphere with sulfur and sulfur compounds. Of all the sugges- tions that have been made, none appear to have given satisfactory results as a varnish of collodion — a solution of gun-cotton in a mixture of alcohol and ether. All other varnishes appear to impart a yellowish tinge to the silver or plated wares, but collodion varnish is quite colorless. The articles should be carefully brushed with the varnish with an elastic brush, making sure that the entire surface is covered. The film of collodion will protect the under- lying metal surface for a long time. SILVERING OF GLASS. (Making of Mirrors.) The former process for making mir- rors is by means of an amalgam of mercury. The following is the process ■said to be in use bv mirror manufac- turers some years ago : A sheet of pure tin-foil, slightly larger than the glass plate to be sil- vered, is spread evenly on a perfectly plane stone table having a raised edge, and is well cleaned from all dust and impurity. This tin-foil must be free from the slightest flaw or crack. The tin is next covered uniformly to the depth of Y% of an inch with clean mer- cury, preference being given by some to that containing a small proportion of tin from a previous operation. The glass plate, freed from all dust or grease, and repolished if necessary, is then carefully slid over the mercury. This part of the work requires skill and DOMESTIC UTILITIES. 1167 experience to exclude all air bubbles, and even the best workmen are not every time successful. If there is a single bubble or scratch the operation has to be repeated and the tin-foil is lost. When this step has been satis- factorily accomplished the remainder is comparatively easy. The glass nlate is loaded with heavy weights to Dress out the excess of mercury, which is collected and used again. After 24 hours the mirror is lifted from the table and placed on edge against a wall, where it is left to drain well for several weeks. At the present time it is customary to make mirrors by causing a deposi- tion of metallic silver on the glass. The latter is first made chemically clean by washing or scrubbing with an alkaline liquid, then rinsing with distilled water. Am- spot or stain, even a momentary touch of a person's finger, is liable to interfere with the uniformity of the de- position of the silver and be the cause of an imperfect mirror. After the glass has been cleaned and drained it is to be laid down flat and over it floated a solution of the silver salt, usually the nitrate with some ammonia added. When the glass is completely wetted, a reducing substance in aqueous solution is added. Various reducing agents are used, such as Rochelle salt, glucose, for- maldehyde, etc. I. Edel's process : Solution A. Silver nitrate av.oz. 1 Distilled water. Ammonia water, each ..... sufficient Dissolve the silver salt in 8 fluid- ounces of distilled water and add am- monia water gradually until the brown precipitate that is thrown down at first is just dissolved, being careful not to add too much ammonia. To make sure that too much ammonia has not been used, drop into the liquid a crystal of silver nitrate and shake; if the solution becomes turbid, no excess of ammonia has been used, and if it does not, more silver must be added till it does be- come turbid. . Then filter the liquid through a double paper filter, returning the first portion of the filtrate to the filter until the liquid runs through clear, and add enough distilled water through the filter to make the filtrate measure 16 fluidounces. Put this in a clean bot- tle, cork well, and keep in a cool, dark place over night. Solution B. Rochelle salt, chemically pure . .... dr. 2 Silver nitrate gr. 10 Distilled water, to make., fl.oz. 16 Dissolve the salt in 10 fluidounces of water, and heat the solution to boiling in a porcelain dish. Then add 10 grains of silver nitrate, stir with a glass rod, and boil the liquid gently for 10 or 15 minutes or until it becomes of a gray color. Filter this paper until clear and add enough distilled water through the filter to make 16 fluidounces of liauid. Put this into a clean bottle, cork well, and place away for 5 or 6 hours. When the preparation is wanted for use, mix Solution A .' fl.oz. 1 Solution B fl.oz. 1 Distilled water fl.oz. 4 Immediately pour this mixture over the glass, which has previously been cleaned as described above, and leveled on some firm support. Then allow to stand un- til the solution has deposited its silver, about one hour being required. Then decant the excess of liquid, rinse off with clear water, and stand the glass on edge to dry. Lastly apply a protective coating of asphaltum varnish, using a soft brush to avoid scratching the sil- ver. SILVERWARE, To Clean. See under Polishing Powders and Silv«r Polish. The following useful points may also be noted here in re- gard to cleaning silverware : Make a thin paste of prepared chalk and sodium hyposulfite, in equal parts, rubbed up in distilled water. Apply this paste to the surface rubbing well with 11 f>8 THE STANDARD FORMULARY a soft brush. Rinse in clear water and dry in sawdust. Ink Stains. Silver articles in domestic use, and especially silver or plated inkstands, fre- quently become badly stained with ink. These stains cannot be removed by or- dinary processes, but readily yield to a paste of chlorinted lime and water. Javelle water, when at hand, may be used instead. Egg Stains. These are easily and quickly removed from silver by rubbing with common salt. A pinch taken between the thumb and finger and rubbed on the spot with the end of the finger will usually re- move the darkest egg stain. To Clean Silver Ornaments. Make a strong solution of soft soap and water, and in this boil the articles for a few minutes — 5 will usually be enough. Take out, pour the soap solu- tion into a basin, and as soon as the liquid has cooled down sufficiently to be borne by the hand, with a soft brush scrub the articles with it. Rinse in boilinq water and place on a porous substance (a bit of tiling, a brick, or unglazed earthenware) to dry. Fin- ally, give a light rubbing with a cham- ois. Articles thus treated look as bright as new. To Frost Polished Silver. Articles of polished silver may be frosted by putting them into a bath of nitric acid diluted with an equal volume of distilled water, and letting remain for few minutes. A better effect may be given by dipping the article frequent- ly into the bath until the requisite de- gree of frosting has been attained. Then rinse and place for a few moments in a strong bath of potassium cyanid, remove and rinse. The fingers must not be al- lowed to touch the article during either process. It should be held with wooden forceps or clamps. SLATING PAINT FOB BLACK- BOARDS. See Blackboard Slating. SNOW IMITATION for Christmas. Ordinary cotton is too dangerous to use for Christmas decorations. The best substance for this purpose is pure white "mineral wool," i. e., asbestos. If this is not available or if it be too ex- pensive, ordinary cotton rendered in- combustible by treatment with a fire- proofing solution may be used. See un- der Fireproofing Fabrics, etc. A more highly decorative effect will be obtained if the cotton is strewed with what is known as "diamond dust." See under heading Diamond Dust. SOAP BUBBLE LIQUID. I. Castile soap av.oz. l / 2 Glvcerin fl.oz. 4 Water fl.oz. 6^ Dissolve the soap in the water and add the glycerin. The latter makes the bubbles tenacious or more permanent. The same effect may be obtained by the use of gum arabic. Bubbles blown with this solution, if cautiously deposited on a soft woolen cloth, will retain their shape for sev- eral hours, and if covered with a glass shade to prevent evaporation will some- times keep for 3 or 4 days. II. The following is also recom- mended : Castile soap, powder av.oz. 2 Mucilage of acacia fl.dr. 2 Glycerin fl.oz. 4. Water, to make fl.oz. 16 Dissolve the soap in a portion of the water, add the other ingredients, and strain. Use about an ounce to a pint of water. SOAP, ARSENICAL. I. Arsenous acid, fine powder.gr. 320 Potassium carbonate gr. 120 Castile soap gr. 320 Lime gr. 40 Camphor gr. 10 Water sufficient DOMESTIC UTILITIES. 1169 Heat the acid and potassium carbon- ate with one fluidounce of water in a porcelain capsule, until the acid is com- pletely dissolved. Then add the soap, in thin shavings, and after this has been thoroughly incorporated, add the lime and camphor previously reduced to powder. Keep the product in well-closed ves- sels. This soap is primarily intended for use by taxidermists. II. This is Toellner's formula : Salicylic acid av.oz. I Borax, fine powder av.oz. y 2 Naphthalin, fine powder. . .av.oz. Yz Arsenous acid, fine powder. av.oz. 5 Soap, fine powder av.oz. 5 Water fl.oz. 10 SOAP, BENZIN. See Benzin Jelly. SOAPS, CLEANING. See under the headings Cleaning Soap; Benzin Jelly; Carpet Cleaners; and Soap, Ox-Gall. SOAP, OX-GALL. This has been highly recommended for its detergent properties. It is said to remove stains of all kinds from fab- rics. Extract of quillaja .av.oz. 1 Borax, powder av.oz. 1 Ox-gall, fresh fl.oz. 4 Common or castile soap, powder av.oz. 15 Triturate together the borax, extract and ox-gall, dissolving as much of the borax as possible. Then add the soap, beat the whole to a uniform consist- ence, and cut into cakes of the desired size. If no extract of quillaja be at hand, soap bark in shreds may be exhausted by boiling with water, straining, and evaporating the liquid on a water-bath. One hundred parts of bark yield about 20 of extract. — D. It has been suggested to add to this 1 ounce of glycerin and about 2 drams of oil of sassafras. II. Oleic acid av.oz. 1 Borax av.oz. 2 Ox-gall, fresh av.oz. 5 Tallow or common soap. . .av.oz. 20 Triturate the borax with the ox-gall ; then thoroughly incorporate with it the soap, previously reduced to powder, ^and lastly incorporate the oleic acid. SOAP, PETROLEUM. I. Emery's formula : Petroleum av.oz. 5 White wax av.oz. 4 Alcohol fl.oz. 6 Marseilles soap av.oz. 10 Mix the petroleum, wax and alcohol in a flask and heat until they are com- pletely dissolved, then add the soap, and dissolve again. Remove the flask from the source of heat, shake until the con- tents assume a creamy appearance, and then pour into molds. The alcohol is not absolutely neces- sary; it merely aids in dissolving the wax and soap. The product contains approximately 25% of petroleum. II. Hager's formula : Petroleum av.oz. 6 l / 2 Domestic soap, dried av.oz. 4^ Japan wax av.oz. 2 Solution of caustic soda, sp.gr. 1.33, av.oz. 2 Water fl.oz. 4^/2 Alcohol fl.oz. 12 Oil of citronella fl.dr. 3 Cut up the soap and wax to fine shav- ings, mix with the water, alcohol, and solution of soda, and heat together until the wax is saponified and a translucent mixture is obtained. With this incorop- ate the petroleum and oil of citronella. The solution of caustic soda may be made from 1 part of dry sodium hy- drate dissolved in 2 parts of water. SOAP, POLISHING. See "Soaps" under Silver Polish. SOAP, SILVER. See under Silver Polishes. SOAP, STEARIN. Stearjic acid av.oz. 2 ' j Sodium carbonate, crystal ... gr. 560 Water fl.oz. 8 Alcohol fl.dr. 2 Sodium chlorid fl.dr. 4 1170 THE STANDARD FORMULARY Dissolve 540 grains of the crystallized sodium carbonate in 6 fluidounces of water; transfer this solution to a water- bath and gradually add the stearic acid with constant agitation ; then add the alcohol; cover the vessel, and allow it to remain upon the bath for 6 hours to separate the soap ; add the sodium chlorid and the remainder of the so- dium carbonate, dissolved in the re- mainder of the water; transfer the whole to a strainer, and when cold Dress out the remainder of the moisture. — D. SOAP, Whale Oil. This may be prepared like the soft soap of the U. S. P., substituting crude fish oil for linseed oil. SOLUTION, Non-Freezing. This is said to make a preparation of this kind: Pearlash ay.lb. 5 Glycerin pints 3 Water, to make gal. ] Mix and dissolve. SOOT FROM STOVEPIPES, To Re- move. See under headings Chimney Cleaners and Stovepipes, To free from Soot. SPONGES, Bleaching of. See Bleached Sponges. SPONGES, USED, To Clean. Different methods have been recom- mended for cleaning mushy, sticky or slimy sponges, such as have been in use around a soda fountain and which are not made clean by a simple washing with soap and water. I. Table salt av.oz. 8 Ammonium carbonate av.oz. 4 Water, hot gal. 1 Dissolve the salts in the water and soak the sponges in this solution for an hour or two, then rinse them in clean water, squeeze them out, and let them dry. II. Wash the sponges in warm water, each gallon of which contains half an ounce of solution of soda, then rinse them in clear water, and transfer to bromin water, allowing them to remain until they become white. Again wash in clear water, transfer to the water containing the solution of soda, and wash once more in clear water to re- move all traces of bromin. Then squeeze as dry as possible and dry by exposure to the sun if possible. STAINS FROM FABRICS, Removal of. Various cleansing preparations are mentioned under the headings Ammo- nia, Household; Benzin Jelly; Cleansing Preparations, Carpet Cleansers; Glove Cleaners ; Mildew Spots, To Remove ; and Soap, Ox-Gall. Before applying any of the cleansers mentioned in this work to colored goods an experiment should be made, either with a sample of the goods or on some portion which will not be seen, to de- termine whether directions given for treating the spot will not affect the color. The tables given herein will be useful to determine in just about what manner fabrics must be cleaned. Whenever a cleansing liquid is men- tioned, it may be any of the prepara- tions mentioned under Cleansing Li- quids, Cleansing Creams, Benzin Jelly, or similar article. The Spot is of Unknown Origin. White Goods. — Dissolve some soao in lukewarm water and add 2 dessert- spoonfuls of "cleansing liquid" and dampen the spot with a sponge soaked in this' solution; finally wash out in clear water. Colored Woolens. — Dissolve a "cleans- ing pencil" in a bottle of the solution and wash out the spot in the liquid; then rinse in clear water, and dry in the air. See Cleansing Pencil. Silk, Satin and Similar Delicate Fab- rics. — Add to the above solution the yolks of two eggs, and spread this on the spot. Then wash in lukewarm wa- ter ; rinse in cold water, and dry by a gentle heat. To press out use an iron that is warm only — not hot. DOMESTIC UTILITIES. 1171 Milk, Soup and Small Grease Spots Generally. White Goods. — Wash with the warm solution of a "cleansing pencil" in wa- ter. See Cleansing Pencil. Colored Cotton or Woolen Goods. — Dampen with a cleansing liquid or cream ; remove the excess of the solu- tion by means of blotting paper, and wash with a solution of a "cleansing pencil." Silk, Satin, Etc. — Dampen by means of a sponge soaked in cleansing liquid, removing any excess by means of blot- ting paper. Grease, Paint, Varnish, Etc. White or Colored Woolens or Cotton Goods. — Moisten several times with a cleansing liquid, lay a piece of blotting paper over the spot and press this with a hot iron. Then wash the whole of the fabric in hot soap suds. Silk, Satin and Delicate Fabrics. — Rub up some "white bole" or talcum to a thin dough with a cleansing liquid, and spread over the spot. When thoroughly dry brush off and wipe with dry bread crumbs. When the Spots are Old. — First moist- en with chloroform and then proceed as above. Stearin, Wax, Etc. First remove as much as possible with a knife ; then lay a damp towel under the spot and put several thicknesses of blotting paper over it and press out with a hot iron. If any stain remains after this, treat as directed under but- ter, grease, etc. Resin, Tar, Axle Grease, Etc. White Goods. — Wet with good oil of turpentine, wring out, cover with blot- ting paper, and go over with a hot iron. Then wash in warm soap suds. Colored Cotton or Woolen Goods. — Moisten the spot, apply butter, soap thoroughly, allow to stand for a few minutes, and then wash with oil of tur- pentine and hot water alternately. If this does not help, spread over the spot 74 the yolk of an egg previously mixed with oil of turpentine; cover with blot- ting paper and press with a hot iron. Then scratch off the residue and wash thoroughly. As a final resort, wash out in water slightly acidulated with hydro- chloric acid. Silk, Satin, Etc. — Drench with chloro- form, and, when this has evaporated, apply white bole or talcum; cover with blotting paper, and press with hot iron. If this does not help, mix some yolk of egg with chloroform and proceed as above, removing the residue by wiping off with bread crumbs. Vinegar, Acid, Wines, Fruit, Etc. White Goods. — Wash out with clear water to which a little "cleansing liquid" has been added. Colored Goods, Whether of Cotton, Wool or Silk. — Moisten with a cleans- ing liquid, allow to evaporate, and then rinse in clear water. Acids. Fresh spots may be removed by put- ting on a drop of a cleansing liquid; old spots cannot be remedied. COLORED Fruit Stains from Peaches, Red Wine, Cherries, Strawberries, etc. White Goods. — Dip in Javelle water or solution of chlorinated soda, and im- mediately that the stain has disappeared wash thoroughly in clear water. Colored Cotton or Woolen Goods. — Wash with hot soap suds, to which a smaller or larger quantity of Javelle water or solution of chlorinated soda, has been added (as the fabric is more or less delicate) ; rinse in water to which a little cleansing liquid has been added; finally, wash in, a large quan- tity of clear water. Silk, Satin, Etc. — Follew directions as above, save to use very dilute solutions. Grass Stains. White Goods. — Wash out with boiling water. Colored Goods, Whether of Cotton, Wool or Silk. — Moisten the spot with a 11T2 THE STANDARD FORMULARY very dilute solution of tin chlorid, and then wash thoroughly in a plentiful sup- ply of clear water. STAINS from Tannin, Green Nuts, etc. Treat with very dilute Javelle water, or solution of chlorinated soda. Coffee or Chocolate Stains. Cover the spot with yolk of egg di- luted with a cleansing liquid; wash out in warm water, and iron, while still moist, on the wrong side of the cloth. Aniline Ink Stains. White Goods. — Wash with alcohol to which a little acetic acid has been add- ed, and then bleach with Javelle water or solution of chlorinated soda. Colored Goods, Whether Cotton, Wool or Silk. — If the color admits of it, fol- low the directions for white goods. If the dye is too delicate for this, wasl. out with strong alcohol alone, as noth- ing else will prove of benefit. See also Ink Erasives; Silver Nitrate Stains, To Remove ; and Rust Stain Re- movers. STAINS FROM THE HANDS, To Remove. When the hands have been stained by strong alkaline solutions, they should be washed in some dilute acid, nitric, ox- alic, or acetic (i to ioo of water). If soap without water is then immediately applied, fatty acids are deposited in the skin, which thus becomes less liable to crack. The effects of the lime solu- tions and also of strong ammonia may be prevented in the same way. After using mineral acids the hands should be washed with water and rubbed while wet with a piece of soap. If the acid is strong or has affected a large sur- face, the hands should be bathed, after washing, in a weak solution of soda (i to ioo). Strong sulfuric acid is first to be washed off as far as possible with plenty of water, after which soap should be employed as previously directed. If water is used abundantly there is no danger of too much heat being evolved. When the acid has caused severe burns, the affected parts may be covered with a paste composed of magnesia, magne- sium carbonate, or sodium bicarbonate with a little water. Nitric acid is re- moved by the same process. Burns by this acid, especially when treated with alkaline agents, are apt to leave behind a yellowness of the affected integument. Nitric acid destroys the epidermis so quickly that it can scarcely ever be re- stored to a normal condition, and this is true also of the fumes of nitric acid, nitromuriatic acid, bromin and chlorin. Iodin stains should be treated with a solution of sodium hyposulfite (i to 10 of water). When the hands have been exposed for a long time to the action of carbolic acid, wash them first with alcohol, which may be used several times over for this purpose, and then with soap, after which, without being first dried, they may be rubbed with wool-fat. After working with subli- mate solutions it is best to bathe the hands for some time in a solution of common salt (i to 50 of water), fol- lowed by soap and wool-fat. Potassium permanganate stains may be removed by rubbing with a solution of oxalic acid, then washing in water, slightly acidulated with sulfuric acid. Potassium bichromate stains may be removed by treating them with a strong solution of sodium hyposulfite, slightly acidulated with sulfuric acid. The same effect may be obtained by touching with sulfurous acid and then washing in rain or distilled water. See also Walnut Stains, To Remove. STAINS FOR WOOD. By wood stains are understood solu- tions of dyes, etc., used for coloring wood. They are fixed on the wood either direct or through the medium of some mordant. In many cases the color is only developed in the grain after the mordant is applied; sometimes the mordant merely changes the tone of the color. The action of the stain is influenced DOMESTIC UTILITIES. 1173 not only by the mordant but also by the natural constituents of the wood, as tannin for instance. Consequently differ- ent woods sometimes give entirely dif- ferent results with a certain stain. All the stains here given have been tried with oak, cherry, white beech, red beech, maple, ash, birch, linden, poplar, fir and pine. Practical utility can best be served by designating the mordants and color solutions with letters and fig- ures respectively and combining them in a tabular form under the colors. A more definite nomenclature of the colors is impracticable because of the variations of color and tone produced on the different woods. Moreover the age of the wood to be stained and other circumstances enter into the matter of color. Mordants. (a) Iron acetate solution. The following consists of solutions of the substance and quantity named in ioo parts of water: (b) 2 parts of potas- sium bichromate; (c) 1 part of copper sulfate and 1 part of potassium chlorate ; (d) 1 part of barium chlorid; (e) 1 part of calcium chlorid; (/) 2 parts' of magnesium sulfate; (g) 2 J / 2 parts of ^manganese sulfate; (h) 3 parts of chrome alum; (f) 1 part of iron chlorid; (k) 2 parts of iron sulfate; (/) 2 parts of copper sulfate; (m) 2 parts of tin chlorid; (w) 3 parts of alum. Coloring Solutions. 1. Dissolve 20 parts of logwood ex- tract in 80 of water. 2. Dissolve 10 parts of logwood ex- tract in 90 parts of water. 3. Dissolve 20 parts of aniline chlorid in 80 parts of alcohol. 4. Rub 10 parts of Cassel brown with 30 parts of 10% ammonia water, put in a bottle and allow to stand corked for 24 hours. Then add 50 parts of water and 10 parts of alcohol. Allow the mix- ture to stand for several days and then filter. 5. Boil 5 parts of caustic potassa and 10 parts of Cassel brown with 50 parts of water for about half an hour, cool, add sufficient water to bring up to 90 parts by weight, and then add 10 parts of alcohol. 6. Triturate carefully 5 parts of ali- zarin with 100 parts of water and add sufficient ammonia water to make solu- tion smell strongly of ammonia. 7. Mix 1 part of alkannin, 10 parts of alcoholic extract of red saunders, 10 parts of dragon's blood and 180 parts of alcohol, and filter. 8. Dissolve 5 parts of alcoholic ex- tract of red saunders and 10 parts of aloes in 85 parts of alcohol and 2 parts of 15% soda solution (sp.gr. 1.17). 9. Dissolve 1 part of gallic acid in 100 parts of water. 10. Dissolve 1 part of water-soluble nigrosin in 140 parts of water. Before applying a stain, the wood should be smoothed by sandpapering. After applying the stain the wood should be polished so as to "bring out" the stain. Other formulas are mentioned below. See also the somewhat similar prepara- tions under the heading Varnish Stains. Some years ago a patent was issued to a German firm for making wood stains from coal-tar dyes dissolved in benzole, oil of turpentine, and similar solvents. These stains, unlike water and spirit stains, do not raise the grain of the wood, so that the usual subsequent process of smoothing is entirely obvi- ated, and any desired shade of color may be obtained by one or two applica- tions. Black or Ebony Stain. Use No. IV in the above table, or one of the following: I. Solution A. Sodium or potassium chlorate av.oz. 1 Copper chlorid av.oz. 1 Water fl.oz. 15 Mix and dissolve. im THE STANDARD FORMULARY Solution B. Aniline chlorid av.oz. 2 l / 2 Water '. . . .fl.oz. 15 Mix and dissolve. The dry wood is painted three times with the above solutions, applying them alternately; before each application the wood is well dried; finally, it is rubbed with linseed oil or a mixture of tur- pentine and wax, and polished. The color is not affected by acids or alkalies. If aniline chlorid be not at hand, use instead 2 av. ounces of aniline oil, 3 av. ounces of hydrochloric acid, and 15 rluidounces of water. This is similar to the procedure men- tioned under Table Tops, To Make Acid-Proof, which see. Cherry Stain. Light-colored woods may be stained in imitation of cherry by the use of these solutions. III. Annatto av.oz. 4 Caustic potassa av.oz. 1 Water fl.oz. 48 Boil until the annatto is dissolved. IV. Logwood chips av.oz. 8 Caustic potassa av.oz. 1 Water fl.oz. 32 Boil until the color is extracted, add- ing more water from time to time, to make up for the loss by evaporation. The stain is to be "fixed" by washing the wood, after its application, with alum water. Mahogany Stain. V. Madder av.oz. 2 Logwood chips av.oz. x / 2 Water fl.oz. 32 Boil together, then strain. This is to be applied to wood while hot and mordanted with an aqueous so- lution of potassium carbonate, 1 dram to the pint. VI. Alkanet av.oz. y 2 Aloes av.oz. 1 Dragon's blood av.oz. 1 Alcohol fl.oz. 16 Reduce the drugs to coarse powder; mix with the alcohol, set the whole in a warm place for 3 or 4 days, agitate oc- casionally, and filter. Before applying, mordant with dilute nitric acid. VII. This is said to be used by French workmen : Make the wood per- fectly smooth, then apply dilute nitric acid, rubbing well into the fiber, and allow to dry. Then macerate i l / 2 av.oz. of dragon's blood with 16 fluidounces of alcohol for several days, agitating occa- sionally, filter, and to the filtrate add l / 2 av. ounce of sodium carbonate. Paint the mixture on the mordanted wood several times until the desired color is obtained. If the color becomes dimmed, linseed oil is to be rubbed into the wood. Oakwood Stain. VIII. First apply to the wood a 15%! solution of soda and allow to dry. Then make a strong solution of catechu in water, about 1 in 3, by boiling with wa- ter, to a pint of liquid add l / 2 ounce of iron-free alum, and apply this liquid, preferably hot, to the prepared wood. Finally, when dry, mordant the wood with a 5% solution of potassium bichro- mate. IX. Purple Stain. Logwood chips av.oz. 8 Potassium carbonate av.oz. 2 Indigo, powder av.oz. 1 Water fl.oz. 48 Boil the logwood with the water till well exhausted, adding water from time to time to restore that lost by evapora- tion, strain, and to the liquid add the other ingredients. Walnut Stain. X. Potassium permanganate, .av.oz. l / 2 Distilled water fl.oz. 16 Apply twice in succession, and after an interval of 5 minutes wash with clear water. A strong hot decoction of green wal- nut shells may also be applied, followed, when partially dry. with a concentrated solution of potassium bichromate. DOMESTIC UTILITIES. 1175 STAMPING INKS. See Inks, Stamping. STAMPING PREPARATIONS. These are employed for stamping em- broideries, etc. Powders of various col- ors are rendered adhesive by admixture with gum resins, such as resin, copal, damar or sandarac. The substances should be made into the most impalpa- ble power by trituration and sifting. The method employed for stamping is to perforate paper according to the pattern desired, then placing this upon the fabric, sprinkling or rubbing the powder into the perforations (carefully removing the pattern), placing a piece of unperforated paper on the cloth, and carefully passing a hot iron over the whole. The iron melts the resin and leaves the design imprinted on the mate- rial. I. Mix equal parts powdered resin and a pigment — ultramarine or Prussian Mue for blue; zinc oxid or flake white tor white ; chrome yellow for yellow ; burnt or raw umber, burnt or raw sien- na. Vandyke brown, etc., for brown ; ivory black for black, etc. II. Resin, Damar resin, Copal resin, Sandarac, Pigment, each, equal parts. Reduce each to very fine powder, and mix well. III. For stamping fabrics liable to be injured by heat, it is suggested to mix the above powders with enough alcohol and using this with a brush like a sten- cil ink. It is said that a tinted starch paste is also used for this purpose. STARCH OR LAUNDRY GLOSS. (Starch Polish or Polishing Starch.) Many women impart a suitable polish to the laundry by adding either borax or paraffin to the starch, but in many cases other prepared compounds are used, such as those mentioned here. These may be in the form of cake, pow- der or liquid. Cake Form. I. Instead of plain paraffin, the fol- lowing may be used: Stearin, pure av.oz. 4 . Paraffin av.oz. 6 M^elt together, pour into molds to so- lidify, and then cut into cakes weighing about Y\ ounce each. In using, make a starch paste, say from one pound of starch, add one of these pieces and leave in the mass dur- ing a few minutes' boiling. When us- ing unboiled starch paste, a small quan- tity of a hot solution of starch contain- ing the gloss is applied to a rag and the latter gently rubbed over the fabric just before ironing. II. Stearic acid (stearin) av.oz. 16 Absolute alcohol fl.oz. 1 Melt the acid, add the alcohol, and form into broad rectangular blocks, which may be wrapped in tin-foil and parchment paper. In using, starch the goods in the us- ual manner, pass the hot iron over the stearin block, and iron rapidly in the usual manner ; a brilliant polish will be produced. The irons must be well cleaned when the ironing is completed as the acid will eventually rust the metal of the irons. — D. Powders. III. Borax av.oz. 4 Gum arabic av.oz. 1 Use both in powder and mix well. IV. Spermaceti, powdered av.oz. 2 Gum arabic, powder av.oz. 2 Borax, powder av.oz. 3 A tablespoonful of this mixture is to be added to about 1 pint of boiled starch while this is being prepared. Spermaceti is readily reduced to pow- der by trituration in a mortar, while keeping it moistened with a few drops of alcohol. V. Spermaceti, powder av.oz. 2 Gum arabic. powder av.oz. 2 Borax, powder av.oz. 3 11T6 THE STANDARD FORMULARY White resin, powder dr. 2 Prepare and use like the preceding. VI. Soap, powder av.oz. 1 Talcum, powder av.oz. 3 Apply this mixture to the right side of the starched article by means of a flannel rag and then iron in the usual way. Liquids. VII. Spermaceti av.oz. 1^4 Acacia av.oz. 1 Borax av.oz. 1 Glycerin fl.oz. 2^ Distilled water fl.oz. 15 Heat together with constant stirring until complete solution is achieved. Let cool, and fill into suitable bottles, which must be well stoppered. Directions: Take -i ounce of good starch, and add just enough cold water to make a paste, carefully rubbing with a spoon until all lumps are broken down. To 1 pint of boiling water add 5 table- spoonfuls of this liquid, pour the whole over the starch paste, and boil for not less than half an hour. These proportions are intended for collars, cuffs, and fine shirt-bosoms. For other articles less of the liquid is required. STORAGE BATTERIES, To Make. See Batteries, Storage. STORM GLASS SOLUTION. See Barometer Glass, Solution for. STOVE POLISH OR BLACKING. I. Plumbago made into a thin paste with solution of sodium silicate or wa- ter glass. This makes an excellent stove polish and should be brushed thoroughly. II. Reduce graphite to an impalpable powder by grinding in a mill with wa- ter, and then dry. Use this with water first, then allow to dry and polish with a brush. This is the base of nearly all commer- cial stove polishes. III. Bone black Plumbago Copperas . Water .av.oz. 8 .av.oz. 8 .av.oz. 2 sufficient Dissolve the copperas in the smallest possible amount of water, strain the so- lution through cotton, and incorporate the previously mixed and sifted pow- ders. The copperas makes the polish more lasting. This paste should be put up in tin boxes. IV. Graphite av.oz. 10 Soot or lampblack av.oz. 2 Copperas av.oz. 4 Glycerin, water, each sufficient Prepare like the preceding, using a mixture of 1 part of alcohol and 2 parts of glycerin as the solvent. The so-called Ceylon graphite is con- sidered the best. Of the soots, so-called American gas black is the best for the purpose, while if bone black be used this should be of the best quality and be deprived of calcium phosphate by treat- ment with hydrochloric acid. V. Bayberry wax av.oz. 1 Mineral oil fl.oz. 13 Plumbago, fine powder. .. .av.oz. 25 Oil of lavender fl.dr. 1 Melt the wax, add the mineral oil, thoroughly incorporate the plumbago, and finally incorporate the oil of laven- der. This is said to be used in France for polishing fine heating apparatus. VI. This is said to make an excellent liquid stove polish. Graphite, fine powder av.oz. 4 Lampblack av.oz. J4 Rosin av.oz. 1 Oil of turpentine or gaso- line fl.oz. 32 Mix thoroughly. This mixture should be kept well shaken while in use, and must not be ; applied when there is a fire or light ' nearby. On this account it cannot be. used on a stove with a fire in it. DOMESTIC UTILITIES. 11' STOVEPIPE ENAMEL. I. Asohaltum av.oz. 8 Linseed oil, boiled av.oz. 4 Oil of turpentine fl.oz. 16 Melt the asphaltum in an iron pot, add the linseed oil, and bring to a boil. Allow to cool sufficiently and then in- corporate the oil of turpentine. IT. Shellac av.oz. 6 Venice turpentine av.oz. 2 Sandarac av.oz. 1 Aniline black dr. 3 Oil of turpentine fl.oz. 3 Wood alcohol fl.oz. 54 Mix and dissolve by agitation, then decant the clear liquid. This will stand a higher heat than asphaltum and is therefore suitable for stove pipes, steam radiator, and similar articles. STOVEPIPES, To Free from Soot Stovepipes may best be cleared of soot by frequently (every few days) throwing strips or pieces of zinc on the hot fire and opening the draught in the chimney. See also Chimney Cleaners. STRAW HAT CLEANERS. These are now usually put up in the form of powder contained in little en- velopes. This powder is frequently ox- alic or tartaric acid; the latter is to be preferred on account of its non-poison- ous character. One dram is to be put up in each package. Other powdery mixtures for the same purpose are the following : Powders. I. Sodium bisulfite av.oz. 5 Tartaric acid av.oz. 1 Borax av.oz. y 2 Mix and put up in packages of half an ounce each. The directions for use are to moisten a small quantity of the powder with water and apply this with a wetted tooth brush to the hat. II. Potassium oxalate, or a mixture of equal parts of potassium bitartrate and oxalic acid may be used for this purpose. III. Sodium perborate is also an ex- cellent hat bleach and cleaner. In us- ing, add about a teaspoonful to 2 fluid- ounces of warm water, spongtf the hat with this liquid, rubbing in thoroughly, then wipe off with a sponge that has been dipped in the solution and then squeezed out. Then apply a weak solu- tion of oxalic or tartaric acid, which is to be allowed to remain for a short time when it is to be washed off and the hat allowed to dry. Liquids. See the preparation mentioned under the heading Panama Hats, To Clean, or use the following : IV. The simplest method is to brush well with dilute ammonia water or weak solution of potassa, then a liberal application of hydrogen peroxid. This is easier to use and is said to be more satisfactory than bleaching with sulfur. V. Sodium dioxid (or peroxid) may also be used as a hat bleach, first wash- ing with a solution in warm water, then wiping repeatedly with the same solu- tion to which more and more oxalic acid has been added until the liquid is decidedly acid. The alkaline solution will make the straw yellow but as acid is added to the liquid the light color will be restored. Finally, rinse the hat with clear water, and dry it. STRAW HAT VARNISH. If a simple waterproof application is desired, apply one of these varnishes, but if a color or dye is wanted, add some aniline dye, sufficient to give the desired tint. For white straw hats, which are to remain uncolored, white shellac should be used in these for- mulas. I. Shellac av.oz. 4 Sandarac av.oz. V/2 Venice turpentine av.oz. y 2 Castor oil fl.dr. 1 Alcohol or wood alcohol. . .fl.oz. 16 Mix and dissolve by agitation. II. Shellac av.oz. 5 Rosin av.oz. 1 1178 THE STANDARD FORMULARY Venice turpentine av.oz. i Castor oil fl.dr. I Alcohol or wood alcohol. . .fl.oz. ij Mix and dissolve by agitatior SULFUR STRIPS. These are made by cutting thick paper into strips and passing through melted sulfur. Cloth strips may be substituted for paper. The temperature must not be too high and care must be taken not to allow the sulfur to ignite. If the first coat is not thick enough, the strips may be dipped a second time. SWEEPING COMPOUNDS. According to a patent issued in 1905, this is composed of sawdust, silicious material, rosin, oil, and tar. Another patent calls for catechu, 1 part, mineral oil, 8 parts, sawdust, 16 parts, bran, ^2 parts, sand, 48 parts, and water con- taining a small amount of nitrobenzene, 32 parts. This is offered as a good formula : Paraffin wax av.oz. 1 Paraffin oil pints 2 Salt av.oz. 4 Sea sand lb. 4 Sawdust lb. 5 Oil of eucalyptus fl.oz. 1 Melt the wax, add the paraffin oil. in- corporate the sand, salt, and sawdust, and finally add the oil of eucalyptus. SYRINGES, HYPODERMIC, To Clean. See under heading Hypodermic Syringes. TABLE TOPS, To Make Acid-Proof. Table and counter tops, such as the tops of laboratory tables and prescrip- tion counters, may be rendered acid- proof by the following treatment: Scrape off the old paint and varnish and scrub thoroughly, then brush on a solution composed of Iron sulfate av.oz. 1 Copper sulfate av.oz. 1 Potassium permanganate .av.oz. 2 Water, to make fl.oz. 24 When the first coat is dry, apply an- other coat, and when this is dry, apply in the same manner two coats of this liquid : Anilin fl.oz. 2 Hydrochloric acid fl.oz. 3 Water, to make fl.oz. 17 Or use 2Yz ounces of anilin hydro- chlorid in enough water to make 17 fluidounces. Finally, when the table top is dry, ap- ply a thin coating of raw linseed oil. The wood assumes an ebony black color, which may be objectionable. The table top may also be rendered acid- proof by first cleaning and scrubbing it, allowing it to dry, and then rubbing in melted paraffin, or the paraffin may be dissolved in gasoline and several coats of this solution may be applied with a brush. The first mentioned preparation is similar to that mentioned under Xo. 1 ebony stain under Stains for Wood. This latter will also render table tops acid-proof. TABLEAU LIGHTS. See Fires. Colored. TAR STAINS, Removal of. See under Stains from Fabrics, Re- moval of. TATTOO MARKS, To Remove. These are said to be removed by the following plan : Wash the part thor- oughly with diluted acetic acid, half an hour after which apply the following: Caustic potash gr. 4 Water fl.oz. 1 After the lapse of another half hour use Diluted hvdrochloric acid. . .fl.dr. 1 Water ...fl.oz. 1 This should be repeated daily. Strong- er solutions may be applied, if neces- sary, if they can be borne by the pa- tient. TELEPHONE SOLUTION. The formula used by the Department of Public Charities (New York) to prepare a solution for scrubbing the mouth-pieces of telephones is as fol- lows : Thymol m. 15 Oil of pinus sylvestris m. 15 Oil of peppermint. ........... m. 15 DOMESTIC UTILITIES. 1179 Alcohol fl.dr. 2 Tincture of green soap fl.dr. 4 Water, to make fl.oz. 16 In the city hospitals of New York the mouth-pieces are "scrubbed" with the above solution once a week. TIN CONTAINERS, To Stick Labels on. See Paste to Stick Labels on Tin. TIN PLATING. See Plating with Gold, Silver, Tin, etc. TONING SOLUTIONS for Photog- raphy. I. Gold chlorid gr. 2 Sodium acetate dr. 1 Distilled water fl.oz. 16 Mix and dissolve. Let stand for 1 or 2 days before using. The following are combined toning and fixing solutions : II. Gold chlorid gr. 8 Ammonium chlorid gr. 15 Silver chlorid gr. 50 Sodium acetate dr. 2 Ammonium sulfocyanid dr. 4 Sodium hyposulfite oz. 4 Distilled water fl.oz. 20 Dissolve the gold and ammonium chlorids in 4 fluidounces of Water and the sodium acetate and hyposulfite and ammonium sulfocyanid in the remainder of the water, mix the two solutions, and finally add the silver chlorid. III. Gold chlorid gr. 2 Lead nitrate dr. 2 Lead acetate dr. 2 Citric acid dr. 2 Ammonium sulfocyanid oz. 1 Sodium hyposulfite oz. 8 • Distilled water, hot '.fl.oz. 32 Dissolve the solids, except the gold chlorid, in the water, filter the liquid until clear, then add the gold chlorid. TOOTH CEMENTS. See under heading Cements. TRACING PAPER. See Paper, Tracing. TYPEWRITER RIBBONS. See under heading Ink for Type- writer Ribbons. VARNISHES. These, like lacquers, are resinous so- lutions intended as protective applica- tions to metals, wood, etc. See also the Lacquers. Amber Varnish. I. Amber av.oz. 8 Oil of turpentine fl.oz. 9 Linseed oil varnish fl.oz. 6 Melt the amber in a closed vessel (out of contact with the air) over a naked flame, allow to cool somewhat, dissolve in the oil, and finally add the varnish. D. II. Amber av.oz. 6 Linseed oil, clarified fl.oz. 16 Oil of turpentine fl.oz. 32 Heat the amber, add the linseed oil, boil until it "strings" well, allow to cool somewhat, then incorporate the oil of turpentine. When required to dry and harden quickly, driers may be added during the boiling. Anatomical Varnish. III. Mastic av.oz. 3 Sandarac av.oz. 8 Camphor dr. 2 Venice turpentine av.oz. 34 Alcohol fl.oz. 28 Mix and dissolve. This is used for dry anatomical speci- mens. — H. Aromatic Varnish. IV. This is suitable for fan boxes, handkerchief cases, glove boxes, etc. : Storax dr. 1 Peru balsam dr. 1 Tolu balsam dr. 1 Extract of licorice dr. 1 Aloes dr. 2 Myrrh dr. 2 Gum olebanum av.oz. l / 2 Mastic av.oz. 2 Benzoin av.oz. 3 Tincture of cinnamon fl.dr. 4 Alcohol fl.oz. 32 1180 THE STANDARD FORMULARY Reduce the solids to coarse powder, mix all the ingredients, macerate for 7 days, agitating frequently, and then fil- ter. Asphalt Varnish. V. Asphaltum av.oz. 8 Oil of turpentine sufficient Melt the asphaltum over a direct flame, allow to cool, reduce to coarse powder, and dissolve in enough oil to make a total weight of 20 av. ounces. The asphalt may also be dissolved in oil of turpentine without the preliminary fusion but the product will make a sticky coating. — D. See also the similar "black varnish." Black Varnish. Linseed oil varnish fl.oz. 10 Burnt umber av.oz. 2 Asphaltum, powder av.oz. 4 Oil of turpentine sufficient Heat the first three ingredients until the asphaltum is dissolved, then remove from the fire and add oil of turpentine until the liquid is of proper consist- ency. — H. See also the similar preparation under the head Bicycle Paint ; also the similar "asphaltum varnish." Bookbinders' Varnish. VII. Shellac av.oz. 4 Benzoin av.oz. i l / 2 Sandarac av.oz. 1 Mastic av.oz. 1 Oil of lavender fl.dr. 2 Absolute alcohol fl.oz. 24 Mix, macerate for some time, agitat- ing occasionally ; decant the clear liquid, and filter.— H. VIII. Shellac av.oz. 4' Benzoin av.oz. 2 Mastic av.oz. 1 Venice turpentine dr. 3 Alcohol fl.dr. 20 Macerate a few days, agitating occa- sionally, and filter. — H. Celluloid Varnish. IX. Pyroxylin (soluble gun cot- ton) dr. 2 Ether fl.oz. 5 Alcohol fl.oz. 10 Camphor dr. 1 Pour the ether over the pyroxylin, add the alcohol and finally add the cam- phor, and dissolve by agitation. This varnish may be colored by the addition of anilines. It is particularly adapted for covering paper labels. — D. A mixture of amyl acetate and wood alcohol may be used as the solvent. Or dissolve 2 parts of celluloid in 20 parts of acetone without heat, agitating frequently, then add 78 parts of amyl acetate, and set aside to clarify. This is similar to Banana Oil, which see. X. Varnish for Chocolate Candy. Sumatra benzoin av.oz. 1 Shellac av.oz. 1 Vanillin gr. 6 -Alcohol fl.oz. 14^ Dissolve the first three ingredients in the alcohol ; filter, and pass enough al- cohol through the filter to make the fil- trate measure 16 fluidounces. — D. Colorless Varnish. XL Any of the colorless varnishes mentioned here may be used, such as celluloid varnish. The following is known as Luning's varnish : Shellac, white av.oz. 2 l / 2 Alcohol fl.oz. 16 Animal charcoal, well burnt and recently heated av.oz. 5 Dissolve the shellac in the alcohol by agitation, boil for a few minutes with the charcoal, and then filter. This is useful for drawings and all kinds of fine work. XII. Sandarac av.oz. 2 Chloroform fl.dr. 4 Oil of lavender fl.oz. 1 Alcohol fl.oz. 10 Mix and dissolve by agitation. Allow to stand until clear. XIII. Dammar av.oz. 3 Acetone fl.oz. 14 Prepare like the preceding. DOMESTIC UTILITIES. 1181 Copal Varnish. XIV. Copal resin . ". av.oz. 16 Linseed oil fl.oz. 12 Oil of turpentine fl.oz. 12 Melt the copal; add the linseed oil, and when nearly cool add the oil of tur- pentine. XV. Co^>al resin av.oz. 13 Oil of turpentine fl.oz. 15 Linseed oil varnish fl.oz. 10 Melt the copal slowly, out of contact with the air, over a naked flame; then pour into a flat dish, allow to cool, and dissolve in the oil by the aid of a gentle heat; finally add the varnish. — D. Dammar Varnish. XVI. Dammar resin av.oz. 8 Oil of turpentine fl.oz. 13 Melt the resin carefully over the di- rect flame; allow to cool, reduce to coarse powder, and dissolve in the oil. This varnish may be prepared by dis- solving the resin without the prelimi- nary fusion, but the product will always be sticky. — D. French Varnish. XVII. This is a name applied to col- ored spirit varnishes made from 1 part of bleached or orange shellac dissolved in 5 parts of alcohol. Wood or dena- tured alcohol may be used instead of alcohol. Allow the liquid to stand and decant the clear portion. To make red varnish, use 1 part of eosin to 49 parts of Lleached shellac so- lution. For blue, use 1 part of aniline blue to 24 parts of bleached shellac so- lution. For yellow, use 1 part of gam- boge to 24 of the solution or 1 part of aniline yellow (alcohol-soluble) to 49 parts of the solution. For golden yel- low, use 2 parts of p-amboge and 1 part of dragon's blood to 47 parts of orange shellac solution. The gamboge and dragon's blood should first be reduced to coarse powder and shaken with some alcohol before adding to the shellac so- lution. For green, use 1 part of aniline green to 49 parts of orange shellac solu- tion. Furniture Varnish. XVIII. Shellac av.oz. 16 Resin av.oz. 1 Alcohol fl.oz. 48 Venice turpentine av.oz. 3 Talc, powder av.oz. 2 Warm the shellac and resin; add the alcohol, and finally, the turpentine and talc. Shake vigorously for several min- utes and stand in a cool place. After 8 days filter through a filter which has been previously wetted with alcohol. — D. Grecian Varnish. XIX. Balsam of fir av.oz. 6 Oil of turpentine fl.oz. 2 Alcohol fl.oz. 4 Mix and dissolve. Green Varnish for Metal. XX. Dissolve 10 parts of sandarac and 3 of mastic in 20 parts of a 30% solution of soda, dilute with 100 parts of cold water, and then add a solution of 10 parts of pure ferrous sulfate and 8 of copper acetate in 200 parts of wa- ter. Allow the precipitate to subside, collect it, wash with cold water, and dry it. Then reduce to powder and dis- solve in oil of turpentine, thin solution of rosin, or copal varnish. Label Varnish. XXI. Sandarac av.oz. 3 Mastic av.oz. $4 Venice turpentine dr. 2 Alcohol fl.oz. 16 Macerate with repeated stirring until solution is effected, and then filter. Paper labels are first sized with di- luted mucilage, then dried, and finally coated with this varnish. If the labels have been written with water-soluble inks or color, they are first coated with two coats of collodion, and then var- nished. — D. XXII. Shellac, bleached av.oz. 5 l / 2 Balsam of copaiba av.oz. x / 2 Venice turpentine gr. 100 Alcohol fl.oz. 16 Prepare and use like the preceding. — D. 118? THE STANDARD FORMULARY XXIII. Sandarac av.oz. i Mastic av.oz. 2 Camphor av.oz. y 2 Alcohol fl-oz. 5 Oil of turpentine, rectified, .fl.oz. 2 Mix, macerate for several days, agi- tate occasionally until dissolved, then allow to stand, and decant the clear liquid. Violin Varnish. XXIV. This is said to make a hard and durable varnish for musical instru- ments : Sandarac av.oz. 1 Shellac av.oz. y 2 Mastic av.oz. J / Venice turpentine av.oz. y 2 Elemi av.oz. Y A Alcohol fl-oz. 14 Mix and dissolve by agitation. The mixture is to be colored light red with cochineal or darker with dragon's blood. VARNISH .REMOVERS. See Paint and Varnish Removers. VARNISH STAINS, Removal of. See Stains from Fabrics, Removal of. WALL-PAPER CLEANER. The following are used : I. Mix together one pound each of rye flour and white flour into a dough, which is partially cooked and the crust removed. To this 1 av. ounce of com- mon salt and y 2 av. ounce of powdered naphthalin are added, and finally 1 av. ounce of corn meal and 1 dram of Venetian red or burnt umber. The com- position is formed into a mass of the proper size, to be grasped by the hand, and in use it should drawn in one di- rection over the surface to be cleaned. II. Pumice stone, powder av.oz. 4 Wheat flour av.oz. 24 Water sufficient Mix the flour and pumice with water to make a stiff dough. Roll this into a round wad 2 or 3 inches in diameter and cut into 6-inch lengths. Enclose each one of these into a tightly-fitting muslin bag and close the ends by sew- ing. Then drop these into a pot of water in active ebullition and let boil for Y\ of an hour to an hour. Then re- move the rolls, allow to cool for about 12 hours, and take off the wrapping as well as the outer harder portion of the rolls. The softer interior part is used for cleaning purposes. SOAP POWDERS. See under Washing Preparations. WASHING PREPARATIONS. The washing preparations mentioned in this connection are such as are rec- ommended and used for washing clothes. These may be in the form of powder or liquid. Washing" Fluids. I. Oil of turpentine added, in the proportion of about 1 fluidounce to a boilerful of water, will assist in cleans- ing, bleaching and disinfecting clothes. The oil should be added to the water used for boiling. Kerosene is also good but oil of turpentine is to be preferred. This useful property of oil of turpen- tine is taken advantage of in some of these washing fluids. II. The most common washing prep- aration in use by housewives is a mix- ture of 1 ounce of powdered borax, 1 ounce of salt of tartar, 2 ounces of am- monium carbonate, and a 1 -pound can of concentrated lye or potash, the whole to be dissolved in 2 gallons of water. Very frequently the borax is omitted. A cupful of this solution is to be used to a boilerful of water. Washing Powders. Washing powders, usually sold to the consumer as soap powders, may be de- scribed in a general way as mixtures of powdered soap, with about its own weight, more or less, of sodium carbon- ate. Some special brands are also made, which in addition contain other deter- gent agents, such as ammonium car- bonate, sal ammoniac or borax, while still others are found, to which filling, in the form of talc, silex, etc., has been added. The soap itself may have been made by any of the processes known — DOMESTIC UTILITIES. 1183 cold, half-boiled, or boiled, settled, or boiled down — and the stock used may have been any fat, or mixture of fats, according to the grade of washing pow- der to be made. Here are some typical formulas : I. Borax Soap Powder: Curd (hard) soap, powder. av.oz. 10 Soda ash av.oz. 6 Sodium silicate av.oz. 4 Borax av.oz. 2 Each ingredient is thoroughly dried, and all mixed together by sifting. II. Sodium carbonate av.oz. 12 Soap, powder av.oz. 2 Borax, powder av.oz. 2 III. According to Jolle's anaylsis, an- other washing powder was found to contain water, 23.37, sodium carbonate, 68.5, sodium sulfate, 1.04, sodium chlor- id, 0.89, iron oxid, etc., 0.47. It is there- fore a mixture of commercial sal soda and sodium hyposulfite. WATCHMAKER'S OIL. The following formulas are offered : I. Paraffin oil fl.oz. 1 Sweet almond oil fl.oz. 10 — H. II. Olive oil, best fl.oz. 16 Tannic acid gr. 160 Talcum, purified av.oz. 1 Table salt av.oz. 2 Water fl.oz. 16 Introduce the oil into a vessel of the capacity of 1 quart-, add the tannic acid dissolved in 3^ fluidounces of water, and agitate thoroughly until emulsified. Set the mixture aside for 8 days, agi- tating frequently and thoroughly; then add the talcum, shake well, and next in- corporate the remainder of the water. Allow to stand for 24 hours, decant the lower aqueous layer, and wash the oil repeatedly with fresh water until the washings no longer give a reaction with solution of iron chlorid. Now pour the oil into an evaporating dish, add ^fhe salt (which must have previously been well dried and rubbed to fine powder), stir the whole frequently during 24 hours,.- and filter through paper. This oil should be introduced into amber bottles of a capacity not greater than 1 fluidounce, which should be well closed and preserved in a cool place. — D. WATER FOR MARINE AQUARIA. See under Sea Salt, Artificial. WATERPROOFING CLOTH. I. Immerse the cloth in a solution of water glass (made by mixing solution of sodium silicate with an equal volume of water) and before quite dry, im- merse in a solution of alum and copper sulfate, each 1 part, in 10 parts water. Dry slowly in the air. II. Make a weak solution by dissolv- ing equal parts gutta percha and paraf- fin in benzol or carbon disulfid, in which the cloth is bathed. Care must of course be exercised in regard to fire during this operation, as well as while drying. A weak solution of wax in benzine is said to be used for the same purpose. Both should be used in suffi- ciently dilute solutions so that the inter- stices of the cloth will not be filled with the compound. III. Dissolve 1 part alum in 5 parts boiling water and make a similar solu- tion with lead acetate. Immerse the cloth first in the alum bath, and, after wringing slightly, in the solution of lead acetate ; a double decomposition takes place, the insoluble lead sulfate and basic acetate of aluminum being formed in the fibers of the cloth. This treat- ment renders the cloth perfectly water- proof, and to a certain extent fire-proof, while it does not render the cloth air tight, a particular advantage in the case of garments. Waterproofing Canvas. IV. Dissolve soft soap in hot water and add to it a solution of iron sulfate. An insoluble precipitate is thrown down which must be collected, washed, dried, and finally mixed with linseed oil, thus forming a paint, which may be applied in the usual manner. 1184 THE STANDARD FORMULARY India rubber, cut small. .. .av.oz. i Linseed oil, boiled fl.oz. 32 Gold size fl.oz. 5 Dissolve the rubber in half the oil by the aid of heat, then add the remainder of the oil and the gold size. Apply 2 or 3 coats, letting each one dry before applying another. Shake well before using. Waterproofing- Paper. VI. A patent has been granted in France for waterproofing paper by the following process : Olive oil, common parts 7 Rapeseed oil parts 7 Linseed oil parts 7 Yellow beeswax parts 2 Oil of turpentine parts 2 Dissolve the wax in the oil of turpen- tine and add the other oils. Apply this with a flat brush to either one or both sides of the paper. VII. A waterproofing preparation for paper cartons and receptacles, patented in the United States in 1905, is com- posed of paraffin wax, 8 parts, paraffin oil, 1 part, Brazilian wax, 3 parts, talc, 6 parts, asbestos, 2 parts, "asbestine," 4' parts, powdered chalk, 1 part, beeswax, 1 part, bayberry wax, 1 part, petrolatum oil, 1 part, ceresin wax, 1 part, and white wax, 1 part. Waterproofing Shoes. See under heading Shoes. Water- proofing for. WAX FOR FLOORS. See Floor Wax in Powder and Floor Wax or Polish, Liquid. WAXED PAPER. See Paper, Waxed. WEDGEWOOD MORTARS, To Re- pair. Pieces of a wedgewood may be united by melting together equal parts of gutta percha and shellac and applying this, melted, to the edges of the broken parts before uniting them. The pieces of the mortar ought to be warmed before ap- plying the cement. WEED KILLERS. To destroy weeds and grass growing in walks and similar places, sprinkle a solution of 1 pound of arsenate of soda in a gallon of water along the path. The commercial arsenate is cheap and is said to form the basis of most of the weed killers of the market. WHALE OIL SOAP. See Soap, Whale Oil. WHITEWASH, To Prepare. See Kalsomine. WICKERSHEIMER'S FLUID. See under Embalming Fluids. WINDOWS, FROSTING AND STEAMING OF, To Prevent. Frosting of windows is best prevented by some system whereby cold air is caused to circulate near the glass. When the construction of the window does not permit openings to be made at its top and bottom into the outer air, holes should be bored through the floor of the window. Under these holes a box should be built with openings into the cellar. In the box should be placed an electric fan so set as to create a current of cold air along the window glass when in action. Frosting and steaming may to some extent be prevented with the following mixture applied to the glass : Soft soap av.lb. 2 Glycerin av.lb. 1 Oil of turpentine sufficient Melt the soft soap in the glycerin with the aid of a gentle heat, and add enough oil of turpentine to give the mixture the consistency of a heavy syrup. This should be applied to the entire inner surface of the glass by using cloths saturated with it. A thin film should be left on the glass, and rubbed off and renewed as needed. Another plan is to apply diluted alco- hol containing 5 or 10% of glycerin. This will prevent steaming and subse- quent frosting of show windows. DOMESTIC UTILITIES. 1181 WINDOW POLISHES. I. Prepared chalk White bole . . . Jeweler's rouge Water Alcohol .av.oz. .av.oz. .av.oz. ..fl.oz. ..fl.oz. Make into a smooth paste and intro- duce into a wide-mouth bottle. Moisten a cloth with alcohol, place upon the window glass a quantity of the paste of about the size of a bean, and rub the latter about on the glass with the cloth until dry and the powder is removed. — D. II. Prepared chalk Vienna chalk Tripoli, fine Castile soap Water av.oz. av.oz. av.oz. av.oz. fl.oz. 4 3 2 2 3 Dissolve the soap in the water by the aid of heat, adding a little more water if necessary, then incorporate the pow- ders, make a homogeneous mass, and form into cakes. When using, apply this composition on a moistened cloth, then rub off with another cloth until clean and dry. WOOD STAINS. See Stains for Wood. WOOD FLOORS, Polishing of. See Floor Wax or Polish, Liquid. ZINC, COLORING. Clean the zinc by washing with dilute sulfuric acid, i to 12, followed by water and scrubbing with a wire brush. Then apply this solution : Copper chlorid dr. 2 Copper nitrate dr. 2 Ammonium chlorid dr. 2 Water fl.oz. 16 Mix and dissolve. Brush this solution on the zinc and allow it to dry. INDEX Abbott's Saline Laxative, 661. A. B. C. Headache Powders, 661 A. B. C. Liniment, 224 Abernethy's Pills, 290, 661 Abernethy's Remedies, 11 Abfuehrendes Brause Pulver, 325 Abican, 661 Abrastol, 679 Abrin (Jequiritin), 661 Absinthium, Tincture of, 510 Absorbent Flannel, 186 Abstracts, 11 Acacia Extract, 900 — Mixture of, 239 — Mucilage of, 247 — Powder Comp., 315 — Syrup of, 400 Acacing, 661 Acamulsia, 661 A. C E. Mixture, 239 Acet-Theocin-Sodium, 662 Acetal (Ethylidenediethylether), 661 Acetanilid Comp., 661 Dr. Bower's, 661 — Dentifrice, 1014 — Elixir of, 53 — Phenylacetanide, 661 — . Powder Ammoniated, 315 — Powder, Comp., 315 — ■ Cantharidal Vesicant, 661 — Acid, Dilute, 11 Solution, 340 — Perfume, 917 Aceto-Salicylate of Antipyrin, 831 Acetoamidomethyl-Salicylic Acid, 683 Acetocaustin, 662 Acetone-Bromoform, 691 Acetone-Chloroform, 705 Aceton Collodion, 742 Acetous Emetic Tincture, 460 Acetophenone, 769 Acetophenone-phenetidin, 791 Acetophyrin, 662 Acetozone (Benzozone), 662 Acetyl-phenylhydrozin, 766 Acetylated Methylene-Diguaicol, 735 Acetylmethylparamidophenol, 796 Acetylsalicylic Acid, 679 Acid Acetic, Dilute, 11 — Bath Salt, 1018 — Carbolic, No. 33, 12 — — Camphorated, 12 Iodized, 12 — — Liquefied, 11 — Gargle, 590 — Hydrobromic, Dilute, 12 — Hydrochloric, Dilute, 12 — Hydrocyanic, Inhalation of, 211 Scheele's, 13 — Hydrofluoric, Dilute, 13 — Hydrophosphorous," 13 Dilute, 14 — Iron Tonic, 511 — Nitric, Dilute, 14 — Nitrohydrochloric, 15 Dilute, 15 — Nitromuriatic, 15 Dilute, 15 — Phosphoric, Dilute, 15 — ■ Prussic, 12 — ■ Sulfuric, Aromatic, 15 — Sulfurous, 15 Acidol (Betaine Hydrochlorid), 662 Aconite Chloroform, 32 — Collodion, 33 — Comp. Pills, 290 — Extract of, 128 — ■ Fleming's Tincture of, 453 — Fluidextract of, 128 — Leaf, Tincture of, 453 — — Leaves, Extract of, 128 — Liniment, 224 — Ointment of, 259 — Plaster, 304 — Root, Tincture of, 453 — Tincture of, 452 — ■ and Chloroform Liniment, 224 Aconitine Liniment Comp, 224 — Ointment, 259 — Oleate, 227 Acorn Water, 526 Acoustic Oils, 572 Actina, 662 Actinomycosis, 620 Actol (Silver Lactate), 663 Addison's Granules of Arsenate of Gold, 663 Adeps Lanae, 543 Adhesives, 1033 Adhesive Plaster, 304, 312 Adhesive and Strengthening Plaster, 312 Adhoesol, 663 Adiantum, Syrup of, 424 Adipatum, 663 Adipogen, 663 Adjuvant Elixir, 53 Administering Medicines to Cattle. 619 Adnephrin Emollient, 663 — Oil Spray, 663 — • Solution, 663 Adonidin, 663 Adonis, Fluidextract of, 128 Adorin, 663 Adrenalin, 664 1188 INDEX. — Chlorid Solution, 664 Adrin (Epinephrin Hydrate), 664 yEschulus Cones, 664 Agaric, Tincture of, 453 — ■ Agaricinic, Agaricic or Laricic Acid, 664 Agathin ( Salicylaldehydemethyl-phenyl- hydrazine, 664 Ague Bitters, Tincture of, 498 Ague Cures, 5545 Agurin (Theobromine-Sodium- Acetate, 664 Airol, Airform, Airogen (Bismuth Oxyiodogallate) (Bismuth Iodosub- gallate), 665 — ■ Paste, 665 Aiken's Tonic Pills, 665 Aitken's Pills, 303 — Syrup, 429 Ajacol-Thanatol, 753 Akaralgia (G. E. Sodium Salicylate Comp.), 665 Alabaster Cement, 1058 Alain's Pomade for the Hair, 665 Alantol, 759 Alapurin, 665 Albargin (Gelatose-Silver), 665 Albert's Remedy, 665 Albespeyre's Vesicatory, 665 Alboferin, 666 Albolene, 666 Albuminate of Iron Solution, 340 Syrup of, 400 Alcarnose, 666 Alcohol, 16 — ■ Ammoniated, 381 • — Denatured, 1033 Alcoholic Extract of Cod Liver Oil, 745 — Eye Wash, 387 Alcoolats, 17 Alcoolatures, 17 Alcooles, 17 Aldol, 666 Alembroth Gauge, 188 Aletris Comp. Elixir, 54, 666 — Cordial, 666 — ■ Elixir of, 54 — Farinosa, Tincture of, 504 — Fluidextract of, 181 — Liquid Extract of, 181 Aleuronate, 666 Algidine, 666 Alhambra Cream, 1023 — Syrup, 1023 Alisma Extract, 900 Alizarni links, 1104 Alkacetamid, 666 Alkaline Antiseptic Solution, 344 — Bath Salt, 1018 — - Elixir of Rhubarb Comp. with Pan- creatin, 667 — Infusion of Rhubarb, 499 —Lotion or Wash, 232 — Ointment, 259 — ■ — Camphorated, 259 — ■ Pancreatin Cordial, 666 — Powder, 666 — Tincture of Guaiac, 478 Alka-Phosphites, 666 Alkalithia, 666 Alkarhein (Alkaline Elixir of Rhubarb Comp. with Pancreatin), 667 Alkathymol, 667 Allingham's Ointment for Hemorrhoids, 667 Alloys, 1033 Allylsulfocarbamide, 861 Allvlthiourea, 861 Allyl Tribromid (Tribromhydrin), 667 Almond Chocolate, 1023 — Bitter, Spirit of, 381 — Bitter Water, 526 — Cold Cream, 936 — Comp, Emulsion of, 111 — Cream, 936, 946 — ■ Emulsion of, 110 — Meal, 956 — Mixture, 110 — Oil, Emulsion of, 110 — Paste, 957 — Powder Comp., 316 — Syrup of, 400 — . Tablets, 955 — Toilet Cream, 946 . Alodonna Pills, 667 Aloes, Acid, Elixir of, 54 > Compound, Decoction of, 46 Pills, 291 Tincture of, 91, 454 — . Crocata, Tincture of, 96 — Extract of, 128 — Fluidextract of, 128 — Glycerite of, 196 — Pills, 290 — Purified, 17 — ■ Tincture of, 453 — Wine of, 533 — and Asafetida, 290 Canella Powder, 316 Iron Pills, 291 Mastic Pills, 291 — — Myrrh, Fluidextract of, 128 — — • — Tincture of, 454 — — > Soda Solution, 340 Aloetic Pow^-r, 316 Aloin, Belladonna and Strychnine Comp., Elixir of, 54 — and Strychnine, Elixir of. 54 — ■ Strychnine and Belladonna, Elixir of, 54 Alpha-Eucaine, 667 Alphanaphthol, 667 Alphazol, 667 Alphol (Alphanaphthol Salicylate), 667 Alphozone, 667 Alsol, 667 INDEX. 1189 Alstonia Constricta, Fluidextract of, 129 — Plaster, 304 — ■ Scholaris, Fluidextract, 148 — with Mercury Plaster, 304 Alterative Bath Salt, 1018 Ammoniacal Ointment, 259 — ■ Compound, 129 Ammoniated Alcohol, 381 — Elixir, 74, 81 — Copper, 39 — Species, 379 — Iron, 212 — Tonic, 739 — Mercury Ointment, 260 Syrup, 670 — Perfume, 927 Althaea Ointment, 267 Ammonio-Chlorid of Iron, 212 — ■ Svrup of, 401 — Ferric Tartrate, 212 — Species, 380 — Sulfate of Copper, 39 Althaeol Cerate, 667 — Tartrate of Iron, 212 Altschaden Wasser, 234 Ammonium Acetate, Concentrated Solu- Alum, Burnt, 18 tion of, 342 — Exsiccated or Dried, 18 Solution, 341 — Gargle, 590 and Morphine, Solution of, 342 — ■ Glycerite of, 196 — 'and Morphine Valerianates, Elixir of, — Porous, 18 57 — Poultice, 313 — ■ Benzoate, Solution of, 342 — Powder Compound, 316, 670 — Bromid, Elixir of, 54 — ■ Suppositories, Urethral, 396 — Chlorid, Mixture of, 239 Aluminated Copper, 39 — — 'Troches of, 515 Aluminum Acetate Gauge, 188 Lotion, 232 — ■ — Ointment, 259 — ■ — and Licorice, Elixir of, 55 — — Solution, 340 — ■ — with Tartar Emetic, Mixture of, — Acetico-Tartrate Solution, 341 239 — « Borotannate, 715 — Citrate, Solution of, 342 — Boro-tartrate, 687 — —Stronger, Solution of, 343 — Naphtholsulfonate, 670 — Iodid, Liniment, 225 — Salicylate, 670, 840 — Oleate, Liquid, 277 — and Sodium Acetate Solution, 34 L — Quinine and Strychnine Valerianates, — ■ Tannate, 670 Elixir of, 57 Alumnol (Aluminum Naphtholsulfon- — - Succinate, Solution of, 343 ate), 670 — Sulfichthyolate, 770 Alunol, 670 — • Valerinate, Elixir of, 55 Alvatunder, 670 — — and Chloral Hydrate, Elixir of, 55 Alypin, 670 — ■ — • Cinchonidine and Iron Pyrophos- — Nitrate, 670 phate, Elixir of, 55 Amandine, 948, 957 — — .and Iron, Elixir of, 56 Amber Oil Liniment, Comp., 224 — ■ — with Cinchonidine, Elixir of, 55 — Varnish, 1179 — • and Quinine, Elixir of, 56 Ambergris Extract, 900 — ■ Iron Pyrophosphate and Qui- — Tincture of, 454 nine, Elixir of, 55 Ameisen Oil, 251 — • Quinine and Strychnine, Amenoretts, 670 Elixir of, 56 Armenian Cement, 1057 — ■ — ' and Strychnine; Elixir of, 56 — Hellebore, Fluidextract of, 182 ■ — Iron Pyrophosphate, Quinine — Ivy, Tincture of, 454 and Strychnine, Elixir of, 56 — Spikenard, Fluidextract of, 179 — ■ — Iron Pyrophosphate and Amido-Acetphenetidin Hydrochlorid, 822 Strychnine, Elixir of, 56 Aminoform, 670 — with Iron and Quinine, Elixir of, 56 Aminol, 670 — 'Valerianate with Iron, Quinine and Amolin Deodorant Powder, 670 Strychnine, Elixir of, 56 Ammonol, 670 and Quinine, Elixir of, 57 Ammonia, Household, 1033 — ■ — with Strychnine, Elixir of, 57 — Liniment, 225 — > — ■ with Sumbul, Elixir of. 57 Camphorated, 225 Amylene Chloral, 670. 721 — ■ — 'Compound, 225 Amylene Hydrate, 671 — Anisated, Solution of, 342 Amylocarbol, 671 — Aromatic, Spirit of, 381 Amyloform, 671 — Spirit of, 381 Amyrol, 671 Ammoniac, Emulsion of. Ill Analan, 671 — Mixture of, 111 Analgen. 671, 832 1190 INDEX. Analgesine, 071, 673 Anti-Constipation Pills, Carson's, 292 Analeptic Pills, 671 Antidiabetin, 669 Analeptine Cordial, 671 Antidiphtherikon, 672 Anasalpin, 671 Antidiphtherin-Klebs, 672 Anasarcin, 671 Antidipsole, 672 Anaspaline, 671 Antidol, 672 Anatomical Varnish, 1179 Antidolor, "Cits," 672 Anazyme, 671 Antidotes to Poisons, 1034 Anemia in Sheep, 636 Antidyspeptic Conserve, 37 Anderson's Pills, 292 Anti-Dyspeptic Elixir, 672 .— Powder, 319 — Pills, 291 Anderson's Scots' Pills (Grana Angeli- Antidiphtheritic Mixture, 239 ca), 671 Anti-emetic Drops, 50 Andrews' Tonic-Hematic Pills, 6Q8 Ami-Fat, 672 Anemic Pills, 668 Antifebrin, 672 Anemonin, 668 Anti-Fermentine, 672 Anemopsis, Fluidextract of, 185 Anti-Fermentive No. 3, 672 Anesthesia by Infiltration, Solution for Antifungin, 672 (Schleich's), 343 Anti-Grippe Pills, 292 Anesthesin, 668 Antihysteric, Tincture or Drops, 455 — Paraphenol Sulfonate, 852 Antikamnia, 672 Anestheto Obtundent, 668 Anti-Kink Hair Pomade, 982 Anesthol, 668 Antikol (Anti-Calor) Anesthyl (Chloryl), 668 Antilupia Tablets, 673 Angel Food, 1023 Antimonial Ointment, 260 Angelica Comp., Spirit of, 382 — Powder, 316 — Root, Fluidextract of, 129 Antimony Chlorid, Solution of, 344 Angier's Petroleum Emulsion, 668 — Pills, Comp., 292 Angioneurosin, 668 — Sulfid, Purified, 18 Angostura Phosphate, 1023 — Wine of, 533 Anhydrosine, 668 Antinervin (Salbromalid), 673 Anhydroorthosulfamidobenzoic Acid, 837 Antineuralgic Pills, 292 Anilipyrin, 668 Antinonin, 673 Animal Charcoal, 29 Antinosin (Tetraiodaphenolphtalein) ,673 Anise, Elixir of, 57 Anti-Pathic Powders, 673 — Powder, Comp., 324 Antiperiodic Pills, 293 — Spirit of, 382 Antiperiodic Tincture, 455 — Water, 523 Antiphlogistine, 673 Aniseed Cordial, 57 Anti-Phthisis Solution, 673 Anisic Aldehyde, 888 Anti-Phymin (Cock's Anti-Bacilli Com- Anisotheobromine, 669 pound), 673 Annidalin, 669 Antiplug, 673 Anodyne Pomade, 224 Antipyonin, 673 Anodynin, 673 Antipyrine (Phenylaimethylpyrazol - Anozol, 669 Phenazone - Analgesine - Parodyne - Antacrid, Tincture, 454 Phenylone - Sedatine - Methozin - Antalgic Saline, 669 Anodynin), 673 Antemesine, 669 — Effervescent Salt, 331 Ant Exterminators, 1033 — Iodid, 775 Anthemis, Extract of, 141 — Mandelate, 867 Anthrarobin, 669 — Salicylate, 673, 839 Anthrasol (Odorless Coal Tar), 669 Antipyrine ferric Chlorid, 740 Antiansemia, 669 Antirheumatic Cotton, 41 Antiarthritin, 669 Antirheumatin, 673, 743 Anti-asthmatic Elixir, 58 Antisapron, 674 Antibilious Phvsic, Fluidextract, 178 Antischlerasin, 674 — Pills, 294 Antisepo, 674 Antibrule, 669 Antisepsin (Asepsin-Bromanilid), 674 Anti-Canker Pills, 292 Antiseptic Cologne, 914 Anti-Catarrhal Pills, Andrew's, 292 — Comp. Pills, 674 Powder, 316, 337 ■ Powder, 674 Anticongestus, 669 — Crede (Silver Citrate), 674 Anticongestus Comp., 669 — Gargle (Dr. Curtis), 67 INDEX. 1191 — Liquid, 674 — Pills, 674 — Powder, Soluble, 316 — Solution, Alkaline, 344 -Lister's, 344 — — Seller's, 345 Thiersch's, 345 — — Volkman's, 345 — Sphenoids, 674 — Spray (Antisepo), 674 — Tablets, 444 — Tooth Powder, 1004 — Vaginal Suppositories, 728 Antiseptin, 675 Antiseptol, 675. Antisudorin, 675 Antispasmin (Narceine-Sodium and Sodium Salicylate), 675 Antispasmodic Tincture, 488 Antistreptococcin, 675 Antitetanic Dusting Powder, 675 Antithermoline, 675 Antithyroidin, 675 Antitoxin, 675 Antitussin, 675 Ants, Oil of, 251 Anytin, 676 Anytots, 676 Apallagin, 676 Apergals, 676 Apetol, 676 Aphrodine, 676 Aphrodisiac Elixir, 676 — Pills, 825 Apic Graveolentis Co., Elixir of, 67 Apiol, 676 Apioline, 676 Apioloids, 676 Apis Mellifica, Tincture of, 457 Aplopappus, Fluidextract of, 151 Apocodeine Hydrochlorid, 171 Apolysin ( Monoparaphenetidin-Citric Acid), 676 Appetite, Loss of, 598 in Cattle, 621 in Dogs and Cats, 647 in Swine, 642 Apples, Ferrated, Extract of, 129 Applications for Blackheads, 967 — for Tan, 970 — for Sunburn, 970 Apocynum Carrabinum, Fluidextract of, 137 Apomorphine Hydrochlorid, Syrup of, 401 — Methyl-Bromid, 736 Apoplectic Spirit, 382 Apostle Salve, 263 Aqua Phagedoenica Nigra, 232 — Naphae, 531 — Regia, 15 — Vulneraria Spirituosa or Vinosa, 18 — Vulneraria Thedeni, 18 Aquamiel, 677 Aquarium Cement, 1036 — Water, 1036 Aqueous Extract of Opium, 168 Arabian Balsam, 677 Arabin, 677 Arbor Vitae, Elixir of, 58 Tincture of, 455, 506 Arecoline, 677 Argentum-Crede, 677, 709 Argentamine ( Ethylenediamine-Silver- Phosphate Solution), 677 Argonin (Silver-Casein), 677 Argyrol ( Silver- Vietllin), 677 Arhovin, 677 Ariom, 1023 Aristochin (Diquinine Carbonic Ester- Carbonyl Quinine), 677 Aristol (Dithymol-Diodid), 678 Aristobol, 678 Aristoquin, 677 Arm-Pit Powder and Paste, 1020 Armenian Pills, 678 Armoracia, Tincture of, 480 Arnica Flowers, Fluidextract of, 129 -Tincture of, 456 — Glycerite of, 196 — Infused, Oil of, 251 — Jelly, 953 — Liniment, 225 — Plaster, 305 — Root, Extract of, 129 Fluidextract of, 129 Tincture of, 455 — Salve, 586 — Tooth Paste, 1009 Arnicated Glycerol of Cantharides, 989 Arnold's (Seth) Anti-Bilious Pills, 678 Arnold's (Seth) Cough Killer, 678 Arolax (Aromatic Laxative), 678. Aromatic Elixir, 58 — — of Blackbeny, 63 of Eucalyptus, 76 Peptonate of Iron and Manganese, 787 . — Fluidextract, 129 — Laxative, 678 — Liquid Pepsin, 370 — Ointment, 272 — Pepsin, 289 -Plaster, 305 — Powder, 316 — Species, 379 — Spirit, 382 — Sulfuric Acid, 15 — Syrup, 402 — Tincture, 456 — Tooth Powder, 1005 — Vapor for Sick Room, 919 — Varnish. 1179 — Water, 526 — Waters, 890 1192 INDEX. Concentrated, 526 — Wine, 533 of Opium, 493 Arophene, 678 Arosia, 1023 Arquebusade, 18 — White, 18 Arrhenal (Disodium Methylarsenate), 678 Arsenated Hemol, 679 Arsenauro (Solution of Bromids of Gold and Arsenic: Barclay), 678 Arsenhemol (Arsenated Hemol), 679 Arsenic, Antidote, 214 — Chlorid Solution of, 346 — Elixir of, 58 — Paste, Dentists', 1036 — Pills, 293 — and Quinine, Elixir of, 58 Strychnine, Elixir of, 58 — Valangin's Solution of, 345 — and Gold Bromid, Solution of, 346 Gold Iodide, Solution of, 346 Iron Chlorid, Elixir of, 58, 68 and Mercury Chlorids, Elixir of, 58 Quinine, Elixir of, 58 Arsenic and Mercury Iodides, Elixir of, 58 Arsenical Caustic, 27 — Powder, Come's, 316 Arsenous Acid, Solution of, 346 — Oxid, Solution of, 345 — and Mercuric Iodides, Solution of, 346 Arsycodile (Sodium Cacodylate), 679 Artemisia, Tincture of, 489 Arthrosia Pills, 679 Artificial Balsam of Mecca, 18 — Musk, 887 — Oil of Cassia, 888 Jasmine, 889 Lemon, 889 — Sulfur Baths, 1017 Artol, 679 Artoline, 679 Asafetida Emulsion of, 111 — Comp. Pills, 293, 297 Tincture of, 457 — Ethereal Fluidextract of, 129 — Mixture of, 111 — Pills, 293 — Plaster, 305 — Suppositories, 396 — Syrup of, 402 — Tincture of, 456 Asaphol. (Calcium Betanaphtholalpham- onosulfonate-Abrastol), 679 Asclepias, Fluidextract of, 172 — Tuberosa, Tincture of, 496 Asepsin, 747 Asepsin, 679 Aseptic or Aseptinis Acid, 679 Aseptin, 679 Aseptine Powder, 679 Aseptol, 679 Aseptolin-Edson, 679 Asiatic Pills, 293 — Tincture, 457 Asparagus, Tincture of, 457 Asphalt Varnish, 1180 Aspidium, Oleoresin, 282 Aspirin (Acetylsalicylic Acid), 679 Asthma in Canaries, 656 Asthma Paper, 284 Astringent and Antiseptic Comp, 680 — Bitters, 21 — Lotion, 232 — Ointment, 260 — Poultice, 315 — and Escharotic Mixture, 378 — Wash, 971 Athenstaedt's Comp. Tr. Iron, 680 Atoxyl. (Metaarsenic Anilid), 680 Atrabilin, 680 " Atrophine, Glvcerite of, 196 — Oleate, 277 — Ointment, 260 — Sulfate, Solution of, 346 — Suppositories, 396 Aubergier's Paste of Lactucarium, 680 — Syrup, 680 Aubepine, 888 Augen Stein, 39 Aurantiorum Comp. Elixir of, 92 Aurcol, 996 Auritone, 680 Aurous Bromid, 751 Australian Fever Bark, Fluidextract of, 129 Autenrieth's Ointment, 260 Authrapurpurin Diacetate, 829 Arena Sativa, Tincture of, 457 Axle Greases, 1036 Ayer's (J. C.) Cherrv Pectoral, 680 — Hair Vigor, 680 — Malaria and Ague Cure, 680 — Pills, 680 — Sarsaparilla, 681 Azalea Extract, 900 Azoa (Rat Virus), 681 BABY POWDERS, 963 Baits for Animals, 1036 Baldness, for, 986 Ball Bluing, 1036 Ballroom Floor Powder, 1036 Balm of Gilead, Factitious, 18 — Parturient, 19 — Spirit of, 385 Balsam, Commander's, 19 — Fioravanti, 19 — Friar's, 19 — Locatelli, 19 — Malta, 19 INDEX. 1193 — Metz's, 19 — Cologne, 914 — Muskat, 20 — Preparations, 101X3 — Nncistoe, 20 — Powder, 1016 — Nutmeg, 20 — Soap Paste, 1017 — of Life, 245 — Tablets, 1016 Honey, 19 _ Bathing Salts, 1018 Mecca', Artificial, 18 Batteries, Dry, 1038 Sulfur, 20 Battery Fluids, 1037 Turpentine, 20 Battley's Sedative (Battley's Solution — Persian, 19 of Opium), 682 — Riga, Factitious, 20 Battley's Sedative Liquid, 369 — St. Victor's, 19 — Solution of Opium, 682 — Swedish, 19 Baume Analgesique, Bengue's, 682 — Traumatic, 19 — ■ de Fioravanti, 19 — Turlington's, 19 Vie, 46 — Universal, 20 — Tranquille, 256 — Vervain's, 19 Baume's Scale, 1039 — Wade's, 19 Baunscheidt, Oil, 251, 682 — Wound, 19 Bayberry, Comp., Ointment, 260 Balsamum Tranfiullans, 256 — Plaster, 305 Balsamic Fumigation, 1102 — Powder, Comp., 317 — Tincture, 458 — Syrup of, 402 Bamboo Brier, Fluid Extract of, 129 Bay Rum, 916 > Bana-Diastase, 681 Beach's Diaphoretic Powder, 319 Banana Liquid, 1036 Bearberry, Infusion of, 210 — Oil, 1036 Beard, Preparation for, 973 Bandages, 21 Bear's Grease, 982 Bandoline, 982 Bearsfoot, Fluidextract of, 130 Baptisia Comp., Pills of, 303 — Ointment, 260 — Ointment, 275 Bechol, 682 — Tincture of, 510 Becker's Eye Balsam, 682 Barberry, Fluid extract of, 130 Beckwith's Hog Cholera Remedy, 6C2 Barber's Itch, 547 Bedbug Exterminators, 1039 Barclay & Harvey's Antibilious Pills, Bedeguar, Tincture of, 478 681 Beecham's Pills, 682 Barium Theobromine and Sodium Sali- Beef and Cinchona, Elixir of, 59 cylate, 681 'Iron, Elixir of 59 Barley, Decoction of, 46 Wine of, 533 — Water, 46 Wine, 533 Barne, Pulver, 322 — Cinchona and Iron, Elixir of, 59 Barometer Glass Solution, 1036 Iron and Strychnine, Elixir of, 59 — Paper, 1037 — Coca and Iron, Elixir of, 59 Barosma, Tincture of, 461 — Elixir of, 59 Barrall's Antiasthmatic Cigarettes, 681 — Iron and Coca, Wine of, 535 Barr's Dental Anesthetic, 681 — Iron and Malt, Elixir of, 59 Barry's Tricopherous, 681 Bee (Honey) Tincture of, 457 Bartholow's Elixir Gentian with Tinc- — Wine and Iron, 533 ture Chlorid of Iron, 681 — Wine of, 533 Barutin (Barium Theobromine and So- Bejean's Gout Specific, 682 dium Salicylate), 681 Belladonna, Alcoholic, Extract of, 130 Basham's Mixture, 355 — ■ Chloroform, 32 Basic Bismuth Dithiosalicylate, 861 — Collodion, 34 Basicin, 681 — Comp., Plaster, 305 — Oil, 681 — Extract of, 130 Basilicon Ointment, 29 — Glycerite of, 196 Basof, 681 — Green Extract of. 130 Bassorin Paste, 681 — Infused Oil of, 252 Batavia Empyreumatic Oil, 256 — Leaves, Extract of, 130 Bateman's Lotion, 682 Tincture of, 456 — Pectoral Drops, 495 — Liniment, 225 Bates' Salve, 681 — Ointment, 260 Bath Bags, 1017 — Plaster, 305 1194 INDEX. Fluid, 34 — Root, Extract of, 130 Fluidextract of, 131 — Suppositories, 396 — Tincture of, 458 Belloc's Charcoal Lozenges, 682 Bell's Syrup of Codeine, 682 Benesol, 682 Bengal Lights, 1040 Benzacetin ( Acetoamidomethvlsalicvlic Acid), 683 Benzaldehvde, 888 Benzalgen, 832 Benzanilid (Phenylbenzamid), 683 Benzartol, 683 Benzin Jelly, 1040 — Petroleum, Purified, 21 — Disguising Odor of, 1041 — Purifying, 1041 — Non-inflammable, 1042 Benzoaric Acid, 746 Benzoated Cerate, 27 — Gauze, 188 Benzoglycine, 683 Benzoic Acid, Troches of, 514 — Aldehyde, 888 Benzoin and Glycerin Lotion, 950 — Comp., Fluidextract of, 131 Tincture of, 458 — Concentrated Tincture of, 459 — Fluidextract of, 131 — Lotion, 950 — Tincture of, 458 Benzoinated Cold Cream, 936 — Collodion. 34 Benzoinol, 683 Benzolvpseudotropeine, Hydrochlorid, 865 Benzonaphthol (Betanaphthol Benzoate) 683 Benzosalin, 683 Benzosol (Benzoyl - Guaiacol - Guaiacol Benzoate), 683 Benzoyl-Guaiacol, 683 Benzoyl Peroxid, 683 Benzozone, 662, 683 Benzylmorphine Hydrochlorid, 820 Berberine and Iron, Elixir of, 60 — Elixir of, 60 Berberis, Fluidextract of, 131 Bergamiol, 888 Bernhigungs Pulver. 320 Berthe's Syrup of Codeine, 683 Beska or Bitre Draaber, 50 Bestucheff's Nervine Tincture, 483 Beta-Eucaine, 683 Betaine Hydrochlorid, 662 Betanaphthol, 683 — Benzoate, 683 — Bismuth, 683 — Salicylate, 683 Bethroot, Fluidextract of, 132 Betol (Naphthalol, Naphtosalol, Sali- napthol, Betanauhthol Salicylate). 683 Betton's British Oil, 690 Betul-Ol, 684 Bevan's Cholera Mixture, 241 Bicycle Chain Lubricant, 1042 — Enamel, 1042 — Oil, Illuminating, 1042 Lubricating, 1042 — Paint, 1043 — Tire Cement, 1043, 1056 Billets of Cocaine, 804 Bimbo Flip, 1023 Biodal, 684 Bioferrin, 684 Bioforin, 684 Biogen, 684 Bioplasm, 684 Birch Tar, Tincture of, 459 Bird Lime, Artificial, 1042 — Seed, Mixed, 656 Birds, Care of, 655 — Eye, Fluidextract of, 128 — Insectivorous, Food for, 656 Bismal (Bismuth Methylenedigallate). 684 Bismon (Colloidal Bismuth Oxid), 684 Bismopepsin Tablets, 684 Bismutan, 684 Bismuth Agaricinate. 685 — and Ammonium Citrate, Solution of, 347 — — Cinchona, Elixir of, 60 Tydrastia, 685 Iron, Elixir of, 61 Pancreatin, Elixir of, 61 Pepsin, Elixir of, 62 Quinine, Elixir of, 62 Strychnine, Elixir of, 62 — Beef, Cinchona and Iron, Elixir of, 60 — Betanaphthol, 685 — Beta-Naphthol Comp., 685 — Carbolate, 822 — Cinchona and Iron, Elixir of, 59 Pepsin, Elixir of, 61 Iron and Pepsin, 60 Pepsin and Strychnine, Elixir of, 61 — Cinnamate, 685 — Cinnamate, 762 — Comp., Mixture of, 239 — Comp., Powder, 337 — Comp., Troches of, 515 — Elixir of, 60 — Formic-Iodid, 685 Ointment, 685 — Glvcerite of, 196 — Hair Dyes, 993 — Iodosubgallate, 665 — Iron and Pepsin, Elixir of, £ 1 INDEX. 1195 and Quinine, Elixir of, 61 Pepsin and Quinine, Elixir of, 61 and Strychnine, Elixir of, 61 — Methylenedigallate, 684 — Nux Vomica and Pepsin, Elixir of, 61 — Oxid, Hydrated, 21 — Oxyiodogallate, 665 — Oxyiodomethyl-Gallate, 774 — Oxyiodopyrogallate, 685 — Oxyiodotannate, 685, 769 — Pancreatin and Pepsin, Elixir of, 62 — Pepsin and Quinine, Elixir of, 62 Wafer Ash, Elixir of, 62 Strychnine, Elixir of, 62 — Phosphate, 685 — Powder, Comp., 317 — Proteinate, 685 — Pyrogallate, 685, 758 — Salicylate, 685 — Solution of, 346 — Subgallate, 685 — Subiodid or Oxyiodid, 685 Bismuthal, 685 Bismuthal or Bismutol, 685 Bismutose (Bismuth Proteinate), 685 Bisol (Bismuth Phosphate), 686 Bisque Syrup, 1023 Bites, Treatment for, 587 Bitter Almond Water, 526 Diluted, 527 — Apple, Tincture of, 470 — Drops, 50 — Elixir, 62 — Metallic Pills, 300 — Species, 379 — Stomachic Drops, 52, 459 — Tincture, 459 — Wine, 92 Bitters, 547 — Astringent, 22 — Restorative and Relaxing, 21 — Spice, 22 Ladies, 22 Bittersweet, Extract of, 132 — Fluidextract of, 132 Blackberry Aromatic, Syrup of, 402 — Balsam, 569 — Brandy, 39 — Compound, Elixir of, 63 — Cordial, 39, 569 — Elixir of, 62 — Root Bark, Comp., Fluidextract of, 132 — — Fluidextract of, 132 Syrup of, 402 Blackboard Paint, 1043 Blackburn's Casca Royal Pills, 686 Black Caustic, 27 — Cohosh Comp., Elixir of, 63 Fluidextract of, 133 Pills, 293 Syrup of, 402 Tincture of, 460 — Draught, 209 — Drop, 522 — Enamel, 1043 — Eyes, For, 549 — Haw, Comp., Elixir of, 63 Elixir of, 63 Fluidextract of, 133 — Inks, 1105 — Liniment, 226 — Lotion, 232 — Mercurial Lotion, 232 — Powder, 317 — Root, Tincture of, 473 — Sulfur, 391 — Varnish, 1180 — Wash, 232 Blacking for Shoes, 1044 — for Stoves, 1044 Bladder-Wrack, Extract of, 133 Blair's Gout and Rheumatic Pills, 686 Blancard's Pills, 299, 686 Blancoline (Al. Paraffin Pur.), 686 Blandine Comp., 686 Blatta Insect Powder, 686 Bland's Compound, 686 — Pills, 298 Bleached Shellac, 1045 — ■ Sponges, 1044 Bleaching Feathers, 1044 — Ivory, 1044 — of Oils, 1045 Blei Esseg, 364 — Wasser, 364 Blennostasine, 686 Blenol (Solution Bismuth and Hydras- tia), 686 Blessed Thistle, Extract of, 133 Blind Staggers, 590 Blistering Cerate, 28 — Collodion, 34 — Liquid, 232 — Paper, 284 — Plaster, 28 Blisters, 590 — for, 608 Cattle, 621 Blizzardine, 1023 Blood, Dried, Defibrinated, 2 — Purifiers, 549 Bloodroot, Comp., Acetated Tincture of, 460 Mixture of, 239 Tincture of, 460 — Fluidextract of, 133 — Syrup of, 402 — Tincture of, 460 — Vinegar of, 522 Blucaloids, 686 Blue Cohosh Comp., Tincture of. 461 — ■ — Tincture of, 460 1196 INDEX. — Inks, 1107 — Mass, 237 — Ointment, 261 — Pencils for Veins, 962 — Pill, 237 — Printing Paper, 1045 Bluing, Ball, 1047 — of Copper, 1047 Gum Barrels, 1047 Blush of Roses, 686 Blutan, 687 Blutreinigung Thee, 381 Boerhave's Anti-Asthmatic Elixir, 687 Boiler Compounds, 1047 Boils, Treatment for, 550 Bolds, Fluidextract of, 134 Boletus Laricis, Tincture of, 453 Boneset, Fluidextract of, 134 Bonjean's Elixir de Sante, 687 Bonnie Belle Cream, 1023 Bookbinder's Varnish, 1180 Boonekamp's Bitters, 687 Boracetanile, 687 Boral (Aluminum Boro-tartrate), 687 Boralid, 687 Boraline, 687 Borated Cotton, 41 — Gauze, 189 — Talcum Toilet Powder, 964 Borax Gargle, 186 — Glycerite of, 197 — Honey of, 203 — Lotion, 233 with Morphine, 233 Borcherdt's Malt Extract with Yerba Santa Comp., 687 'Bordeaux Mixture, 1090 Bordet's Hair Tonic, 687 Borhaver's Vegetable Stomach Pre- servative, 687 Boric Acid, Glycerite of, 197 — and Tanuric Acids, Glycerite of, 197 — Ointment, 261 Borine, 687 Borneol Isovalerianate, 688 Bornyral (Borneol Isovalerianate), 688 Boro-Chloretone, 688 Boro-Fluorine, 688 Boroformol, 688 Boroformalin (Boroformol), 688 Boroglyceride, 23 Boraglycerin, 23 — Cold Cream, 936 — Glycerite of, 197 Borol, 688 Borolyptol (Formolyptol), 688 Boromenthol, 688 Boro-Naphthol Soap, 688 Borophenol, 688 Borosal, 688 Boro-Salicylate, 688 Borosalyl, 688 "Boss" (Prescription 49), 688 Botot's Eau Dentifrice (Eau de Bo- tot), 689 Bottle Capping Mixtures, 1048 Bottles, Cleaning Greasy, 1049 Bougies, 23 Boules de Mars (Boules de Nancy), 689 Boules de Nancy, 689 Bourdalle's Ethyl-Methyl Chlorid Mix- ture, 689 Boulton's Solution, 253 Bovinine, 689 Bovista, Tincture of, 497 Bowels, Inflammation of in Cattle, 621 Boyveau-Laffecteur Root, 689 Bracelin Remedy for Diphtheria, 689 Bradycrotine, 689 Brain, Inflammation of, in Dogs and Cats, 647 Branding Ink, 1113 Brandreth's Pills, 689 Brandsanal, 689 Brandt's Swiss Pills, 690 Brandy, Blackberry, 39 — Mixture of, 239 — Proof, 23 Brassicon, 690 Brass Plating, 1050 — Polishes for, 1050 Brayera, Fluidextract of, 156 — Infusion of, 207 Brayerin, 780 Brazil Wood, Test Solution of, 347 Bread Poultices, 313 Breast Tea, 380 Breath Perfumes, 1015 Briant's Sirop Antiphlogestique, 690 Brick Walls, Removing Efflorescence. 1051 Brilliantines, 996 Brinkerhoff's Ulcer Specific, 690 British Oil, 252 British Oil (Betton's British Oil), 690 Brodie's Liniment, 231 Bromalin (Bromethylformin), 690 Bromamid (Tribromanilin Hydrobro- mid, 690 Bromanodyne, 690 Brom-Eigon, 690 Bromelia, 889 Brom- Ethyl, 732 Bromethylformin, 690 Brometone (Acetone-Bromoform), 691 Bromidine, 691 Bromid of Ammonium, Elixir of, 63 Caffene, Elixir of, 63 Calcium, Elixir of, 63 Gold and Arsenic, Solution of, 347 Lithium, Elixir of, 63 — ■ Potassium, Elixir of, 63 Sodium and Supulin, Elixir of, 64 INDEX. 1197 ■ Sodium, Elixir of, 64 Bromides. Syrup of, 403 Bromid of Zinc, Elixir of, 64 Bromine-Iodine Compound, 691 Brominol, 691 Bromin, Solution of, 347 Bromipin, 691 Brom-Lecithin, 691 Bromo-Calteine, 691 Bromochinal (Bromoquinol Quinine Di- bromsalicylate), 691 Bromocoll, 692 Bromodine, 692 Bromoform, 692 . Bronchial Anodyne, 692 Bromo-Hemol (Hemol Bromid), 692 Bromol (Tribromphenol-Bromphenol), 692 Bromolein, 692 Bromo-Mangan (Liquor Ferri-Man- gani Bromopeptonate "Dieterich"), 693 Bromophtharin, 693 Bromoquinol, 693 Bromoquinol, 691 Bromotan (Methvlene Bromtannin Urea), 693 Bromphenol, 692 Brom-Protylin, 693 Bromural, 693 Bronchiline, 693 Bronchitis in Cattle, 621 Bronchoids, 693 Bronchol, 693 Bron's Injection, 693 Bronson's Ointment, 985 Bronze Paints, 1051 Bronzing Gun Barrels, 1052 Broom, Compound, -Decoction of, 46 — Fluidextract of, 134 — Infusion of, 204 — Juice of, 218 Brotanilid, 693 Brown Arquebusade, 18 — Cerate, 27 — Drops, 50 Browning Gun Barrels, 1052 Brown Ink, 1107 — Mixture, 564 — Ointment, 261 — Plaster, 310 Brown's Hair Dye, 693 Brown's Male Fern Vermifuge, 693 Bruises, For, 549 Brust Pulver, 321 Brust Thee, 380 Brunswick Cooler, 1024 Bryst, The, 380 Bryony, Fluidextract of, 134 — Tincture of, 461 Sucher and Jumper and Potassium Ace- tate, Elixir of, 134 Comp., Elixir of, 64 Pareira Comp., Elixir of, 65 Fluidextract of, 134 Potassium Acetate, Elixir of, 65 — Comp., Elixir of, 64 Fluidextract of, 134 — Elixir of, 64 — Fluidextract of, 134 — Infusion of, 204 — Juniper and Potassium Acetate, Elixir of, 64 Uva Ursi and Potassium Acetate, Elixir of, 64 — Pareira and Uva Ursi, Fluidextract of, 134 — Tincture of, 461 Buckbean, Extract of, 134 Buckingham's Whisker Dye, 693 Buckhorn Berries, Syrup of, 403 — Bitterless, Fluidextract of, 135 — Elixir of, 65 — Extract of, 135 — Fluidextract, 135 — Palatable, Fluidextract of, 135 — Syrup of, 403 — Tincture of, 461 Budding Wax, 1096 Buffalo Moths, to Exterminate, 1053 Bugeand's Tonic — Nutritive Wine, 694 Bulkley's Solution of Tar, 377 Bullrich's Salt, 694 Bull's Blood Syrup, 694 Bumsted's Gleet Cure, 694 Bunion Cures, 554 — Burdock, Fluidextract of, 135 — - Seed Compound, 694 Burgundy Pitch Plaster, 306, 311 Burin — Dubuisson's Lozenges of Lac- tate of Soda and Magnesia with Pep- sin, 694 Burin's Pills of Iron and Manganese Carbonate, 694 Burnett's Disinfecting Fluid, 378 — Cocaine, 694 Burnishing Ink, 1160 Burn Ointment, 261 Bursa Pastoris, Tincture of, 502 Burns and Scalds, 551 in Cattle, 622 Burnt Alum, 18 Burnt Sponge, Artificial, 389 Burow's Solution, 340 Bust Developers, 943 Butipyrine, 694 Butler's Elixir of Brandy, 694 Butterfly Weed, Tincture of, 496 Buttermilk Tablets, 781 Butternut Bark, Extract of. 136 Fluidextract of, 136 Butter of Antimony, 344 Butvl-Chloral Hydrate (Croton Chloral Hydrate), 695 1198 INDEX. Elixir of. 74 — Chlorid, Solution of, 348 Syrup of, 403 — Chlorhydrophosphate, Svrup of, 403 Rutyromel, 694 — Esoloate, 696 Bvni Extractum, 160 — Glycerophosphate, 696 Bynin, 694 — Glycerophosphate, Syrup of, 403 — Amara, 694 — Guaiacol-Sulfonate, 754 — Emulsion, 694 — Hypophosphites, Elixir of, 65 Ryno-Hemoglobin, 695 — Typophosphite, Syrup of, 412 Bvno-Hvpophosphites, 695 — Ichthyol, 696 Bynol, 695 — Iodid, Elixir of, 65 Byrolin, 695 Syrup of, 404 — Lactophosphate, Cinchona and Iron, CACAO, TINCTURE OF, 461. 66 Cachet Hemo-Calx, 695 Elixir of, 66 Cachous, 1015 Syrup of, 404, 422 Cacodyle Bengue Pills, 695 with Iron, Syrup of, 405 Cacodvlic Acid (Dimethylarsenic Acid), — Manganese and Potassium Hypophos- 695 phites, 412 Cactus Grandiflorus, Extract of, 136 — Monorioclobehenate, 837 Fluidextract of, 136 r- Oxysulfuret Solution of 348 Tincture of, 462 — Peroxid, 751 Cade, Oil of, Factitious, 252 — Phosphate, Elixir of, 66 Cafetonique, 695 Syrup of, 405 Caffeine, Citrated, 23 — Sulfichthvolate, 771 — Elixir of, 65 — Sulfid, 24 — Hydrobromide, Effervescent Salt. 331 Trituration of, 512 — Sodio-Benzoate, 23 — and Iron Hypophosphites, Syrup of, — Sodio-Benzoate, 695 412 — Sodio Cinnamate, 695 Sodium Hypophosphites with Tar, — Sodiocinnamate, 762 66 — Sodio-Salicylate, 23, 695 Syrup of, 412 — Sulfocarbolate (or Sulfophenate), with Cinchona, Elixir of, 66 695 — — with Malt, Elixir of, 66 Caffeo-Bromide Compound, 695 Calder's Saponaceous Dentifrice, 696 Caffeotanilid, 695 Calendula Ceratie, 28 Caffeotanilid Compound, 695 — Cream, 947 Cajuput Comp., Mixture of, 239 — Fluidextract of, 136 — Liniment, Comp., 220 — Fluidextract of Nonalcoholic, 137 — Spirit of, 383 — Jelly, 953 Calabar Bean, Extract of, 136 — Juice of, 218 Tincture of, 462 -Oil, 252 Calamine Cerate, 27 — Tincture of, 467 — Ointment, 261 — Toilet Cream, 947 Calcalith, 696 Calisava Cordial, 696 Calamus Confection, 37 — Elixir of, 66, 69 — Extract of, 136 — Fluidextract of, 142 — Fluidextract of, 136 — Tincture of, 467 — Tincture of, 462 Calolactose, 696 Calcanro (Solution of Bromid of Gold, Calomel Ointment, 262 Arsenic and Calcium), 695 — and Jalap Powder, 317 Calcarated Extract of Malt, 163 Calomelol, 696 Calcaria Acetica, Hahnemann Solution — Ointment, 697 of, 347 Calox, 696 Calcidin, 696 Camellia, Fluidextract of, 181 Calcimine, to Prepare, 1054 Camphacol, 697 Calcium Acetate, Solution of 347 Campho Ichthyol Ointment, 697 — Betanaphtholalphamonosulfonate, €79 Camphoid. 697 — Bromid, Elixir of, 65 Campho-Phenique, 697 — Bromid, with Iodids Comp., Elixir Powder, 697 of, 81 Camphor Ball, 955 — Carbonate Compound with Colchi- — Carbolized, 24 cine, 696 — Cerate, 28 INDEX. 1199 — Chloral. 24 — Cold Cream, 93d — Comp. Pills, 293 Tincture of, 492 — Cream, 24, 94 — Drops, 50, 384 — Embrocation, 226 — Ices, 954 — Julep, 24 — Liniment, 226 — Liniment Ammoniated, 226 — Liniment, Comp., 226 — Mixture, Acid or Hopes, 239 Aromatic or Parrish's, 240 Comp., 240 — Monobromated, Emulsion of, 120 — Ointment, 262 — Phenate, 697 — Powder, Comp., 317 — Saturated, Tincture of, 463 — Spirit of, 383 — Tincture of, 462 — Toilet Cream, 947 — Water, 527 — and Menthol, 24 Camphorated Carbolic Acid, 12 -Chalk, 1007 --Chloral, 24, 30 --Chloroform, 32 --Cold Cream, 936 --Menthol, 24 --Naphthol, 802 --Phenol, 12, 822 — Phenol-Petrogen, 697 — Tincture of Soap, 229 — Tooth Powder, 1005 — Tooth Paste, 1010 — Wine, 535 Camphoric Acid, 697 Camphoroxol, 697 Camphossil, 697 Canada Pitch Plaster, 306 — Snake-Root, Comp., Syrup of, 405 Canadian Hemp, Fluidextract of, 137 Canary Bird Food, 656 Cancer, Local Treatment for, 552 —Plaster, 306 — Powder Esmarch's, 317 Cancroin, 698 Cande's Lait Antephelique, 698 Candied Sweet Flag, 37 Canker of the Ear, in Dogs and Cats, 647 — Sore Mouth, 552 Cannabin Tablets, 698 Cannabine Tannate, 698 Cannabis Indica, Alcoholic or Resinous Extract, 137 Cigarettes, 698 Extract of, 137 Fluidextract of, 137 Resin of, 327 Tincture of, 463 Canquoin's Paste, 286 Cantelope Sunder, 1031 Coutaridal Collodion, 34 Cantharides Cerate, 28 — Liniment, 226 — Oil, 252 — Ointment, 262 — Ointment, Veterinary, 262 — Paper, 284 Cantharides Plaster, 28, 306 Calisaya Cordial, 696 — Plaster, Veterinary, 306 -Perpetual, 306 — Tincture of, 463 — Vinegar of, 522 — Collodion, 34 Capillin, 698 Caprenalin, 698 Capsella, Tincture of, 502 Capsicum Comp., Plaster, 306 Capsic-Digest Tablets, 698 Capsicol, 698 Capsicum, Fluidextract of, 137 Capsicum Liniment Comp., 227 — Ointment, 262 — Oleoresin, 281 Ointment, 270 — Poultice, 313 — Plaster, 306 — Stronger, Tincture of, 464 — ■ Tincture of, 463 — Troches of, 515 — and Lobelia, Troches of, 515 — and Myrrh, Tincture of, 464 Capsolin, 698 Capsules, Gelatin, Sealing of, 24 Captol, 698 Caramel Syrup, 1024 Caraway, Spirit of, 383 — Water, 527 Carbonate of Ethyl and Phenyl, 736 Carbenzol, 699 Carbolate of Iodin Inhalant, 699 — of Sodium, Solution of, 348 Carbolated Catgut Ligatures, 26 — Chloral, 30 — Cotton, 42 — Jute, 220 — Protective Oiled Silk, 337 — Salicylic Collodion, 34 — Tooth Powder, 1005 Carbolic Acid, No. 33, 12 Camphorated, 12 Glycerite of, 197 Liquefied, 11 Iodized, 12 Solution of/348 Suppositories, 397 Troches of, 515 — Gargle, 590 — Mouth Wash, 1014 1200 INDEX. — Paste, 286 — Salve, 586 — Smoke Ball, 699 Carbolicum, Glycerincum, 197 Carbolineum Avenarius, 699 Carbolized Camphor, 12, 24 — Gauze, 189 — Oil, 252 — Paper, 1054 — Water, 527 Carbonyl Quinine, 677 Carbo-Peptine Wafers, 699 Carbon Paper, 1054 Carbuncles, Treatment for, 550 Cardamon, Tincture of, 464 — Comp., Fluidextract of, 138 Spirit of, 383 Tincture of, 464 Carduus Benedictus, Extract of, 133 — ■ Marianus, Tincture of, 489 Caripeptic Liquid, 699 — Powder, 699 — Tablets, 699 Carl-Aperient, 699 Carlsbad Salt, Artificial, 328 — Salt Effervescent, Artificial, 331 Carmelite Spirit, 385 Carminative Mixture, 240 — Mixtures, 571 — Oil, 252 — Pills, 293 — Tincture, 465, 511 — Water, 527 Carmine, Solution of, 348 Carnation Flip, 1024 — Float, 1024 Carnogen, 700 Carnolin, 700 Carnos, 700 Caroid, 700 Carpet Beetles, to Exterminate, 1054 — Cleaners, 1054 Carrageen, 195 Carriage Top Dressing, 1054 Carriere's Compound Syrup of Enealvp- tol, 700 Carron Oil, 227 Carrot Poultice, 313 Carter's Solution, 348 Carson's Anti-Constipation Pills, 292 Carvacrol, 700 Carvacrol Iodid, 773 Cascanata, 700 Cascara Aromatic. 138 Syrup of, 405 — Carminative, 700 — Carthartic Pills, Hinckle's, 294, 700 — Comp, Pills, Robin's, 700 — — (Sydenham), 700 Tonic Laxative, 700 — Cordial, 700 — Evacuant, 700 — Laxative Tablets, 701 — Peptonoids, 701 — Potent, Fluid, 701 — Sagrada Comp., Elixir of, 67 — - — Elixir of, 66 Fluidextract of, 138 Fluidextract Water-Miscible, 141 Syrup of, 405 Tincture of, 465 Wine of, 535 Aromatic, Fluidextract of, 138 Bitterless or Tasteless, Fluidex- tract of, 140 — Tonic Laxative Globules, 701 Cascarenna. 701 Cascarets, 701 Cascarilla, Extract of, 141 • — .Infusion of, 205 — Tincture of, 465 Cascarin, 701 Cascarin Comp., Tablets, 701 Cascarine-Leprince, 701 Cascaroids, 701 Cascaroma, 701 Case-Aromatic, 701 Casein Cement, 1056 — Ointment, 262 Casey's Cholera Mixture, 241 Cassia Compound, 701 — Fistula Pulp, 325 — Oil of, Artificial, 888 Cassia Water, 529 Cassie or Acacia Sachet, 920 Castanea, Fluidextract of, 141 Castillon's Elixir, 67 Castor, Ammoniated, Tincture of, 465 Castoroids, 702 Castor Oil Hair Pomade, 981 Mixture, 240 Palatable Emulsion of, 112 — Hebaic, Tincture of, 466 — Tincture of, 465 — Water, 527 Catalgine, 702 Catalpa, Oil of, 889 Catalysin, 702 Catani's Specific, 702 Catarrh in Horses, 600 — Pills, 294 — Remedies for, 553 for Dogs and Cats, 648 — Snuff, 337 Cathartic Elixir, Comp., 67 — Pills, Comp., 294 Cataplasms, 25, 313 Cataplasm of Kaolin. 25 Catawba Frappe, 1024 Caterpillar Lime, 1055 Catechu, Troches of, 515 — Comp., Fluidextract of, 141 Infusion of, 205 Tincture of, 466 INDEX. 1201 — Powder, Com., 316 Catgut, Alcohol, 26 — Ligatures, 25 Carbolated, 26 Chromicized, 26 Formaldehyde, 27 Mercuric Chlorid, 27 Oil Juniper, 27 Cathartics, 558 — Veterinary, 601 Catholicons, 702 Catnip Poultice, 314 Cat Remedies, 646 Cattle Medicines, 619 Caulophyllin, Comp. Pills, 702 Caulophyllum, Fluidextract of, 133 — Tincture of, 460 Caustic, Arsenical, Ratier's, 27 — Black, Valpearis, 27 — Filhos\ 27 — Vienna, 27 — Soda, Solution of, 373 Cauvin's Pills, 702 Cayenne Pepper, Tincture of, 463 Cayeaux Nipple Ointment, 702 Cazenave's Lotion, 234 "C. C." Cough Mixture, 567 Cealgie, 702 'Ceanothus Comp., Syrup of, 405 Cearin, 27 Celandine, Tincture of, 466 Celastrus, Fluidextract of, 151 Celery, Caffein and the Bromides, 702 — Comp., Elixir of, 67 — Cordial, 702 — Fluidextract of, 141 — and Guarana, Elixir of, 67 Celoidin, 702 Cellotropin, 702 Celulin, 702 Cellulo, 702 Celluloid Cement, 1056 — Ink for Writing on, 1119 — Varnish, 1180 Cements of All Kinds, 1055 Cephalopin, 702 Ceralin (Koempel), 703 Cerasorum, Elixir of, 67 Cerate, 29 Cerates (Alphabetically arranged), 27, 30 Ceratum Aeruginis, 28 — Tiglium, 28 — Viride, 28 Cereus Grandiflorous, Fluidextract of, 136 — Grandiflorous, Tincture of, 461 Cerevisine, 703 Cerolin, 703 Cetiacol, 703, 813 Cetraria, Decoration of. 46 — Gelatin, 195 Chable's Sirop Astringent, 703 Chair-Leather Polish, 1059 Chalk Mixture, 240 — Troches of, 516 — with Opium Powder, 318 — Powder, Aromatic, 317 Comp., 318 Chalybeate, Pills, 298, 703 — Wine, 538 Chambard's Purgative Tea, 703 Chamois Skin, to Clean, 1059 Chamomilla Comp., 703 Chamomile, Extract of, 141 — Infusion of, 205 — Infused, Oil of, 253 — ■ Comp., Tincture of, 466 — Roman, Fluidextract of, 141 — Water, 527 — ■ — Concentrated, 528 Channing's Solution, 368 Chapman's Mixture, 243 Chapoteaut's Morrhuol, 703 — Phospho-Glycerate of Lime, 703 Charcoal, Animal, Purified, 29 — Poultice, 314 — Powder, Comp., 318 — Tooth Powder, 1005 — (Wood) Trituration of, 465 Chartae, 284 Chaulmugra Ointment, 263 Chelidonium, Tincture of, 465 Cheltenham Salt, 703 Chemical Food, 428, 703 — Garden, 1060 Cherries, Elixir of, 67 — Syrup of, 406 Cherry Blossom Extract, 900 — Egg Bounce, 1024 — Laurel Water, 528 — Water, 528 Chestnut, Fluidextract of, 141 Chevalier's Life for the Hair, 703 Chian Turpentine, Emulsion of, 112 Chichester Mixed Treatment Pills, 703 Chicken Cholera, 655 Children's Cough Cure, 567 Chiniaphila, Fluidextract of, 172 Chinaphthol, 832 China Tincture, 467 Chinese Ink, 1114 — Punch, 1024 Chinoformin, 703 Chinoidin, Tincture of, 466 Chinol, 704 Chinoline, 704 Chinopyrin, 704 Chinosol, 704 — Mouth Wash, 1014 Chinotroptn, 704 Chiodrastis, 704 Chirata Compound, 704 — Elixir of, 68 1202 INDEX. — Fluidextract of, 142 — ■ Tincture of, 466 — Infusion of, 205 Chloraethoform, 704 Chlora-Kaline, 704 Chloralamid, 704 — Elixir, 704 Chloral-Ammonium, 704 Chloral-Antipyrine, 769 Chloralbacid, 704 Chloral Caffeine, 704 — . Camphorated, 30 — Carbolated, 30 Chloralformamide, 704 Chloral Hydrate Suppositories, 397 and Ammonium Valerianate, Elixir of, 68 Elixir of, 68 Chloralia, 704 Chloralimid, 705 Chloral Mentholated, 30 Chloralose, 705 Chloral Phenol, 24 — Svrup of, 406 Chloralum, 705 Chloral-Urethane, 868 — with Camphor, 24 — and Bromjd Comp., Mixture, 240 Chloralamid, Elixir of, 68 Chlorate of Potassium, Glycerin Solu- tion of, 200 Chlorbutanol, 705 Chloretone, 705 — Inhalant, 705 Chloric Ether, 383 Chlorids of Iron and Arsenic, Elixir of, 68 Arsenic and Mercury, Elixir of, 68 Chlorin Gargle, 590 — Inhalation of, 210 — Poultice, 314 — Solution of, 348 — Water, 528 < Chlorinated Lime, Solution of, 348 — Potassa, Solution of, 349 — Soda, Solution of, 349 — Tincture of Iron, 483 Chlor-Lactated Pepsin Powder, 705 Chlorobrom, 705 Chlorodyne, 30, 241 — Cough Cure, 566 Chloroform Anodyne, 241 — Camphorated, 32 — Comp., Elixir of, 68 — Elixir of, 68 — Emulsion of, 112 — Glycerite of, 198 — Liniment, 227 — Mixture of, 112 — of Aconite, 32 — of Beladonna. 32 — Oils, 253 — i Paregoric, 68 — Spirit of, 383 — Water, 529 — and Cannabis Indica Comp., Mix- ture, 241 Chlorol, 705 Chlorolin, 706 Chloro-Phenique, 706 Chlorophenol, 706 Chlorsalol, 706 Chloryl, 668, 706 Chocolate Candy Varnish, 1180 — Frappe, 1024 — Nectar, 1024 — Punch, 1024 Cholelysin, 706 Cholera Drops, 50 — Mixtures, 241, 243 — Pills, 293 — Remedies, 563 Chologestin, 706 Chondrus Comp., Syrup of, 416 — Gelatin, 195 — Jelly, 195 Christadoro's Hair Dye, 706 Christensen's Cholera Mixture, 241 Chroatol, 706 Chromicized Catgut Ligatures, 26 Chromic Acid, Solution of, 349 Chromosot, 706 Chrysarobin, 706 — Cellodion, 34 — Ointment, 263 Comp., 263 Chrysarobin, Triacetate, 737, 785 — Oxidized, 706 Church Incense, 930 Churchill's Syrup, 706 Cicutine Hydrobromid, 711 Cigarettes/ Cubeb, 32 Cimicifuga, Elixir of, 63 — Extract of, 132 — Syrup of, 402 — Tincture of, 460 — Comp., Tincture of, 460 Cina, Tincture of, 510 Cinchona, Aromatic, Wine of, 535 — Detannated, Elixir of, 70 — Tincture of, 467 — Elixir of, 69 — Extract of, 142 — Ferrated, Tincture of, 468 — Fluidextract of, 142 — Gentian and Iron Chlorid, Elixir of, • 71 Malate, Elixir of, 71 — Infusion of, 205 — Iron and Pepsin, Elixir of, 72 Phosphorous. Elixir of. 72 Strychnine, Elixir of, 72 — Pepsin and Strychnine, Elixir of, 72 tNDEtf. 1203 — Syrup of, 406 — Tincture of, 467 — Wine of, 535 — Comp., Elixir of, 70 Fluidextract of, 143 Tincture of, 467 — and Coca Wine of, 536 Elixir of, 536 Hypophosphites, Elixir of, 71 Iron, Elixir of, 72 "Protoxid," 72 Pepsin, Elixir of, 72 Strychnine, Elixir of, 72 — Cinchonia Mixture, 707 Cinchonidine, Elixir of, 72 — Iron and Strychnine, Elixir of, 73 — and Iron Elixir of, 73 Cincho-Quinine 707 Cineraria Maritina 707 Cinnamic Acid, 707 — Addelhyde 888 Cinnamon, spirit of, 383 — Syrup of, 406 — Tincture of, 469 — Comp., Tincture of, 469 — Drops, 50 — Powder, Comp., 318 — Water, 529 Cinnamylic Acid 707 Cinnamylmeta cresol 762 Citarin 707 Citon Tablets 707 Citral 887 Citrate of Iron, 213 Quinine and Strychnine, 217 and Quinine Soluble, 217 and Strychnine 217 Citrated Caffeine, 23 Effervescent Salt, 331 Citric Acid, Syrup of, 406 Citrine Ointment, 268 Citro-Iodid of Iron, Syrup of, 419 Citronellol 888 Citrophen. 707 Citrosandalene 707 Citrozen 707 Citrurea 707 Claret Glace 1025 — Kondike 1025 Clarified Honey, 203 Clarifying Powder, 318 Clarke's Blood Mixture 707 Clare 1025 Clavin 707 Claxton's Gout and Rheumatic Oil, 708 Clay Ointment, 263 Clay's Doctor, Emulsion, 112 Cleaning Copper Drain Boards 1060 — Greasy Bottles 1060 Cleaning Preparations 1060 Cleary's Asthma Powder, 708 Clemens' Solution, 371 76 Clerambourg's Grains de vie, 708 Clermont's Syrup of Arseniate of Iron, 708 Clifford's Shampoo Compound 708 Chri's Lecethine 708 Chinton's Cascara Active 708 Claflin's Mistura Phosphor Co., 707 Cloftlin Emulsion 708 Close's Cholera Mixture, 241 Cloth Cleaning Compounds 1062 Clove Pink Extract 900 Sachet 920 Clover (Japan) Extract 900 — White, Tincture of, 469 Cloves, Infusion of, 205 Club Moss, Tincture of, 488 Clysters, 123 Coal Tar, Solution of, 349 Coating Pills, 294 Cobb's Pills 708 Coca Aromatic Wine of, 536 — Caffeine 708 Cocadrenine' Suppositories, 708 Coca, Elixir of, 73 — Fluidextract of, 143 — Glycerite Suppositories 708 — ■ Tincture of, 469 — Comp., Elixir of, 73 — and Guarana, Elixir of, 73 — and Phosphorous, Elixir of, 73 — with Beef, Wine of, 536 Cocaine Carbolate 708 — Formate 708 — Ointment, 263 — Oleate, 278 — Phenate 708 Cocapyrin 709 Coccia Pills 709 Cocculus Indicus Ointment, 263 Tincture of, 469 Cochia Pills, 295 Cochineal Color, 36 — Mixture, 243 — Tincture of, 469 Cocillana, Syrup of, 406 Cockroach Destroyers 1062 Cock's Anti-Bacilli Compound, 673 — Anti-Phymin 709 Cocoa Butter Cold Cream 937 — Camphor Ice 954 — Emollient 955 — or Cacas Milk 949 Cocoaine 709 Cocoanut Oil Hair Dressing 979 Pomade 981 Codal 834 Coddington's Asthma Powder 709 Codeine Brommethylate 734 — Cough Sedative 709 — Elixir of, 73 — Syrup of, 407 — and Terpin Hydrate, Elixir of, 73 1204 NDEX. Codliver Glycerine 709 — Oil, Aromatized or Palatable, 253 Emulsion of, 113 Extract of, 143 Phosphatic, Emulsion of, 119 Phospharized Emulsion of, 119 Stronger, Emulsion of, 119 Wine of, 536 with Coca Emulsion of, 116 with Cresote and Hypophosphites, Emulsion of, 116 with Hypophosphites, Emulsion of, 117 of Calcuim, Emulsion of, 117 Calcium, Sodium and Potas- sium, Emulsion of, 117 with Lactophosphate of Calcium, Emulsion of, 117 with Phosphate of Calcium, Emul- sion of, 118 with Phosphates of Calcium and Sodium, Emulsion of, 118 with Phosphate of Sodium, Emul- sion of, 119 with Phosphorus, 254 with Quinine, 254 with Wild Cherry, Emulsion of, 119 Coe's Dyspepsia Cure 709 Coffee, Green, Fluidextract of, 143 — Maltrose 1025 — Roasted, Fluidextract of, 144 — Syrup of, 407 — Tincture of, 470 Coirre's Solution, 709 Colalin, 709 — Laxative, 709 Colchi-Sal, 709 Colchicine Salicylate Capsules, Trochet, 709 — Salicylate Comp. Tablets, 709 Colchicum, Vinegar of, 522 — Wine of, 536 — Comp. Tincture of, 470 — Com, Extract of., 144 — Root, Extract of, 144 — Root, Fluidextract of, 144 Wine of, 536 — Seed, Fluidextract of, 144 Tincture of, 470 Wine of, 537 Colcothar, 1130 Cold Cream, 272 — Creams, 931 Containing Petrolatum, 933 Containing Wool-Fat, 934 Greaseless or Non-Greasy, 934 with Animal Oil, 932 with Mineral Oil, 933 with Vegetable Oil, 932 without Water, 934 Cold-in-the-Head, Remedies for, 553 Coley's Mixture, 709 Colic in Cattle, 622 Sheep, 636 Swine, 643 — Oil, 252 — Remedies, 601 Collaform, 709 Collargol, 709 — Ointment, 710 Collas' Capsules of Iron, 710 Collaurin, 710 College Ice, 1031 Collin's Disinfecting Powder 710 Collodion, 33 Collodions (alphabetically arranged), oo, oo Collodion Cotton, 325 — with Cantharides, 34 Colloidal Bismuts Oxid, 684 — Calomel, 696 — Gold, 710 — Mercurv, 769 — Silver, 709 Collosin, 742 Colloxylin, 325 Colocynth, Extract of, 144 — Tincture of, 470 — Comp., Extract of, 144 Pills, 295 — Pulp, 325 — Seed, Tincture of, 470 — and Henbane Pills, 296 Podophyllum Pills, 296 Colorless Fluid Extract of Hydrastic, 352 Colsaloids, 710 Colsathyl, 711 Col-Solules, 710 Cologne Water, 912 with Musk, 913 Coloring Electric Light Globes, 1062 Metals, 1062 Colorless Hydrastis, 710 — Varnish, 1180 Colors for Hair Oils and Pomatums, 980 Perfumery, 892 Columbo, Extract of, 145 — Fluidextract of, 145 — Infusion of, 205 — Tincture of, 470 Comedones, 967 Comfrey Comp., Wine of, 537 Commander's Balsam, 19, 458 Common Strengthening Plaster, 306 Complexion Powders, 958 — Tablets, 960 Composing of Perfumes, 893 Composition Powder, 318 Compound Almond Milk, 111 — Alum Powder, 711 — Camphor Cerate, 954 INDEX. 1205 — Calomel Pills, 292 — Cathartic Pills, 294 — Diachylon Plaster, 309 — Elixir of Guarana, 67 — Elixir of Orange, 540 Peptonate of Iron, Manganese and Quinine with Arsenic, 761 Potassium Bromid, 240 Turkey Corn, 74 Viburnum Opulus, 74 — Glycerin Cream, 954 — Iron Pills, 292 — Liniment of Turpentine, 231 — Lithia Tablets, 711 — Powder of Antimony, 316 Bayberry, 318 Bismuth, 337 Ipecac, 321 and Opium, 319 — Sage Gargle, 590 — Solution of Thymod, 344 Spirit of Lavender, 487 — White Pine Pectoral, 711 — Wine of Cocoa, 876 Concentrated Liniment, 228 — Paregoric, 170 — Solutions, 349 Concentrations, 36 Concrete Oils, 886 Condition Powders, 602 Condurango, Liquid or Fluidextract, 145 Tincture of, 471 — Wine of, 537 Condy's Fluid, 373 Disinfectant, 711 Cones, Homeopathic, 37 Coney Fizz, 1025 Confections, 37, 39 Confection of Almond, 316 Conicine, 711 Coniine Hydrobromide, 711 — Inhalation of, 210 Conium, Fluidextract of, 145 — Infused, Oil of, 254 — Juice of, 218 — Ointment, 263 — Solution of, 350 — Tincture of, 471 Conklin's Salve, 711 Conserve of Hollyhock, 37 Conserves, 39 Constipation Cures for Horses, 603 — in Sheep, 636 — Remedies for Cattle, 623 — Remedies for Dogs and Cats, 648 — Remedy for Birds, 656 Consuelo Face Powder, 959 Consumption in Cats, 648 Controdolin, 711 Convallamarin, 711 Convallarin, 711 Convallaria Flowers, Fuildextract of, 159 Convallaria, Tincture of, 471 Convoloulin, 843 Cook's Electro-Magnetic Ointment, 711 — Pills, 296 Cooling Lotion, 233 — Powder, 319 — Wash, 233 Cooper's Consumptive Syrup, 405 Copaiba, Mass of, 235 — Pills, 296 — Comp., Mixture, 243 — Comp., Pills, 296 — Tincture of, 471 Copal Varnish, 1181 Copeland's Cosmetic Water, 936 Copper, Aluminated, 39 — Ammoniated, 39 — Acetate, Tincture of, 471 — Bluing of, 1062 — Browning of, 1062 — Citrate, 715 — Drain Boards, to Clean, 1063 — Hair Dyes, 993 — Mixture, 243 — Nucleide, 715 — ■ Nucleinate, 715 — Plating, 1063 — Polishes, 1063 — Subacetate Cerate, 28 Ointment, 263 Coptis, Fluidextract of, 153 Copying Pads, 1063 — Paper, 1063 Coral Ink, 1108 Corassa Compound, 711 Cordial Analptine, 712 — Blackberry, 39 — Exalginique, 712 — Pas-Carnate, 712 Cordials, 39 Cook's Impervious and Acid Proof, 1063 Corn, Collodion, 35 — Cures, 563 — Meal Poultice, 314 — Silk, Fluidextract of, 146 — ■ Smut, Tintcure of, 471 Cornus, Fluidextract of, 148 Cornutine Citrate, 712 Cornitol, 712 Corpula, 712 Corrective Mixture, 712 Corrigens, Elixir of, 107 — Syrupus 442 Corrosive Sublimate Catgut. 27 Cotton, 43 Gauze, 192 Jute, 220 Cortexalin, 712 Corydalis, Fluidextract of, 181 --Tincture of, 472 1206 INDEX. Comp. Tincture of, 472 — Comp. Elixir of, 74 Syrup of, 407 Coryfin, 712 Cosaprin, 712 Cosmetic Jellies, 952 — Pomades, 955 Cosmetics, 930 Cosmetique, 997 Cosmi's Powder, 316 — Bouquet Extract, 900 Cotarmine Hydrochlorid, 712 — Hydrochlorid, 852 — Phthalate, 712 Coto, Fluidextract of, 146 — Saccharated Extract of, 146 — Tincture of, 472 Cotton, Absorbent, 39 — Alembrath, 41 — Root Bark, Fluidextract of, 146 Cottons, 39, 45 Cotton's Tonic, 511 Couch Grass, Extract of, 146 Fluidextract of, 146 Liquid Extract of, 147 Tincture of, 472 Cough Drops, 239 Coudray's Eau de Quinine, 712 Cough Powder, 319 — Tablets, 713 Coughs in Horses, 604 — Remedies for, 564 Counterfeit Coin Detector, 1063 Court Plaster, 307 Cowhage, Tincture of, 472 Crab-Apple Flower Extract, 900 Cram's Fluid Lightning, 713 Cramp Bark Comp., Elixir of, 74 Fluidextract of, 147 Tincture of, 509 Vionans Tincture of, 472 Comp., Tincture of, 472 Cramp Drops, 50 Cranberry Poultice, 314 Cranesbill, Fluidextract of, 152 — Infusion of, 207 Crategine, 888 Crayons, for Writing on Glass, 1063 Crealbin, 713 Cream, Camphor, 24 Creams Containing Almond, 948 Cream Cordial, 1025 — of Cod Liver Oil, 713 — Pineapple, 1025 Creek Indian Remedy, 129 Creme Celeste. 272 — DeLa Violettes, 939 — de- Swift, 1025 — Duchesse, 939 — Marquise, 939 Cremoline, 713 Creoferrate Elixir, 713 Creolin, 713 — Gauze, 190 Creosal, 713, 857 Creosin, 713 Creosotal, 713 Cresote Capsules, 713 — Carbonate, 713 — Inhalation of, 210 — Iodid, 713 — Iodid, 714 — Mixture, 243 — Mixture Comp., 713 — Ointment, 263 — Oleate, 713 — Phosphate, 713 — Phosphite, 714, 824 — Pills, 296 — Salicylate, 714 — Tannate, 714, 857 — Valerianate, 714, 729 Creosotide, 714 Creosotonic, 714 Creo-Terpin Comp., 714 Crescent Sherbet, 1025 Cresalol, 714 Cresolene Capsules, 714 Cresol, Comp., Solution of, 1350 — Iodid, 714 — Salicylate, 714 — Salol, 714 — Water, 529 Crespigny's Pills, 291 Crethol, 714 Creuse's Tincture of Iron, 484 Crockery Cement, 1056 Crocus Martes, 1063 Crotalus, Solution of, 350 Croton Bug Exterminators, 1063 Croton-Chloral Hydrate, 695, 714 Elixir of, 74 and Quinine, Elixir of, 74 Syrup of, 407 — Oil Cerate, 28 Collodion, 34 Liniment, 227 Comp., 227 Trituration, 512 Troches of, 516 Croup Remedies, 568 Crude Malate of Iron, 129 Crurin, 714 Cryogenine, 714 Crvostase, 715 Crysol, 715 Crystal Hair Pomades, 981 Crystallose, 715 Cubanade, 1025 Cubeb, Fluidextract of, 147 — Oleoresin, 281 — Syrup of, 407 — Tincture of, 473 — Troches of, 516 INDEX. 1207 — Cigarettes, 32 Cucumber Cold Cream, 937 — Cream, 937 — Juice, 939 — Milk, 949 — Ointment, 939 — Pomade, 939 — Toilet Cream, 947 Cudbear, Tincture of, 473 — Comp., Tincture of, 473 Culture Fluids, 45 — Medium, 45 Culver's Root Extract of, 147 Root Fluid Extract of, 147 Tincture of, '473 — — Comp., Pills, 300 Powder, 319 Cumarin, 887 Cupid's Kiss Extract, 901 Cuperated Hemol, 715 Cupricitrol, 715 Cuprohemol, 715 Cuprol, 715 Cuprum Acetate, Solution of, 350 Curacao Cordial, 74 — Elixir of, 74 — Spirit of, 383 Curare Tincture of, 473 Curaril, 715 Curarine, 715 Curacuma, Tincture of, 507 Curd Soap, 338 Currant Jelly, 286 — Paste, 286 Curwin's Hog Powder, 715 Cusparia, Infection of, 205 Cusso, Fluidextract of, 156 — Infusion of, 207 Cutal, 715 Cuticle Cream, 943 Cutting of Glass, 1064 Cyclamen, Tincture of, 473 Cydonium, Mucillage of, 249 Cypri-Bromides, 715 Cypridol, 716 Cypripedium, Fluidextract of, 157 Powder Comp., 319 Cystitisin Horses, 590 Cystopurin, 716 Daffy's Elixir, 501, 716 Dalby's Carminative, 240 Elixir, 716 Dallman's Tamarinden Essenz, 716 Damholid, 716 Dammar Varnish, 1181 Damiana, Elixir of, 74 — Iron and Phosphorus, Elixir of, 75 — Fluidextract of, 147 Nux Vomica and Phosphorus, Elixir of, 74 — Nux Vomica and Phosphate Elixir of, 75 — Phosphones and Strychnine, Elixir of, 74 Dance-Hall Powder, 1064 Dandelion Comp. Pills, 196 — Elixir of, 74 — Extract of, 147 — Fluidextract of, 148 — Juice of, 218 Dandruff Remedies, 983 Daniel's Concentrated Tinct. Passiflora — Pineapple Phosphates, 716 Darley's Prophylactic Fluid, 716 Darpin, 717 Darwin's Liniment, 717 Davy's Urinal Cakes, 717 Davis Cough Mixture, 567 Day's Kidney Pad, 717 Decoctions, 46-48 Decoction Lignorum, 379 — Sarsae Composition, 47 Deer Suet, 391 Defibrinated Dried Blood, 22 Dehant's Purgative Pills, 717 Dehorning of Cattle, 623 \ Delbarre's Sirup de Dentition, 717 Denarcotized Opium, 282 Denatured Alcohol, 1064 — Olive Oil, 1064 Dental Antiseptic, 1065 Dentalone, 717 Dental Cement, 1056 — Surprise, 717 Dentists' Amalgam Fillings, 1065 — Arsenic Paste, 1065 — Molding Wax, 1065 Deodorant Solution, 379 Deodorized Opium, 282 Depilatories, 1000 Derby Liniment, 717 Deret's Bi-Iodized Elixir, 717 Dericin, 717 Derival, 717 Dermamol Ointment, 717 Dermasapol, 717 Dermatin, 717 Dermatol, 718 Dermatologic Pastes, 286 Dermogen, 718 Deshler's Salve, 29, 718 Detergal, 718 _ Dethan's Bastilles of Potassium Chlor- ate, 718 Developers for Photographs, 1065 Dewberry Root, Co., Elixir of, 75 Dewees' Carminative, 245 — Tincture of Guaiac, 478, 718 Dextrin, Mucilage of, 248 — Syrup of, 408 Dextrinated Paste, 287 Dextroform, 718 Dextro-Quinine, 718 Dextro-Saccharin, 718 1208 INDEX. Diabetes in Sheep, 637 Diabetin, 718 Diacetyl-Morphine, 718, 762 Diethylsulfondiethyl-methane, 858 Diacetyltannin, 856 Diachylon Plaster, 308 Diacodii, Syrupus, 430 Dialysed Iron, Solution of, 357 Diamon Cement, 1057 — Dust, 1066 — Ink, 1114 Diaphtherin, 718 Diarrhea in Cattle, 623 — in Sheep, 637 — in Swine, 643 — Mixtures, 241-243 — Remedies, 569 —Remedy for Birds, 656 — Remedies for Dogs and Cats, 648 — Remedies for Horses, 604 Diastase, 718 — and Pancreatin, Essence of, 123 Diastasic Essence of Pancreatin, 123 Diastin, 719 Diazyme Essence, 719 Glycerole, 719 Dibromethane, 733 Dibromogallic Acid, 746 Dick's Wonder Salve, 719 Dickson's Improved Anaesthetic, 719 Didyminum Salicylate, 719, 723 Diethvlenediamine, 825 Diethylmalonylurea, 873 Diethylbarbituric Acid, 719 Diethylsufondimethylmethane, 853 Difluordiphemyl, 719 Digalen, 719 Digestive Comp., Elixir of, 75 — Hypophosphites, 719 — Pills, 719 — Powder, 319 Digitalin Comp. Elixir, 719 Digitalis, Ethereal, Tincture of, 474 Extract of, 148 Fluidextract of, 148 — Infusion of, 206 — Juice of, 218 — Tincture of, 473 Tincture, Fat-Free, 474 Digestol, 719 Digitoxin, 270 Diguaeacdolmethylene, 754 Di-Iodo-Hydroxy-Propane, 776 Diiodoform, 720 Di-Isobutyl-Cresol Iodid, 737 Dill Water, 529 Dilute Acetic Acid, 11 — Hydrobronic Acid, 12 — Hydrochloric Acid, 12 — Hydrocyanic Acid, 12 — Hydrofluoric Acid, 13 — Hypophosphorous Acid, 14 i f — Muriatic Acid, 12 — Nitric Acid, 14 — Phosphoric Acid, 15 Dimethylarsenic Acid, 695 Dimethylcarbinol Chloroform, 796 Dimethylpiperazine Tartrate, 789 Dimethylxanthine, 859 Dinner Pills, 291, 296 Dioviburnia, 720 Dionin, 720 Dioscorea, Troches of, 520 Diosmal, 720 Dioxogen, 720 Diphthericide, 720 Diphtheritic Powder, 720 Dips, Sheep, 639 Dipsomania Tablets, 720 Diquinine Carbonic Ester, 677 Discs, 49 Disinfectants, 1066 Disinfecting Solid, 717 — Spray for Sick Rooms, 919 Disks, Homeopathic, 50 Disodium Methylarsenate, 678 Dispnon Tablets, 720 Distilled Extract of Witchhazel, 184 — Water, 529 Dita, Fluidextract of, 148 Dithymol-Diiodid, 678 Diurazin, 720 Diuretic Comp., 210 — Elixir, 75 — Pills, 302 — Species, 379 — Wine, Trousseau's, 537 Dixon's Pills, 721 Doan's Backache Kidney Pills, 721 — Dinner Pills, 721 Dobell's Solution, 373 Dodd's Kidney Pills, 721 Dog Grass, Tincture of, 472 Dog Medicines, 646 Dogwood, Fluidextract of, 148 Dolomol, 721 Doloran Tablets, 721 Dolichos, Tincture of, 472 Domestic Preparations, 545 — Utilities, 1033 Donovan's Solution, 346 Dormiol, 721 Dorsenia, 722 Doses for Cattle, 619 — Rules for, 1072 Douche, Nasal, 50 Dover's Powder, 321 — Powder, Camphorated, 319 — Powder, Syrup of, 416 — Tincture, 482 Dow's Phvsic, 290 — White Liquid Physic. 722 Drain Boards, to Clean, 1063, 1072 Draining Ink, 1114 INDEX. 1209 Dried Alum, 18 Driers for Paints, 1072 Driffield Oils, 722 Dr. Klopper's Wheat Albumin, 748 Drops, 50 Drunkenness, Unger's Cure for, 868 Dry Scalp, Ointment, 991 — Shampoo, 976 Duboisine Sulfate, 722 Duffey's Cathartic Elixir, 722 Diuretic Elxir, 848 Dulcamara, Extract of, 132 Dulcin, 722 Diuretin, 721 Diuretic Oil Capsules, 721 Diurol, 721 Dunbar's Hay-Fever Serum, 826 — Serum, 722 Dunlap's Cholera Mixture, 242 Duo Peptonate, 722 Duotal, 722 Duothal, 722 Duotonal, 722 Dupuytren's Hair Pomade, 722 — Pills, 722 Duran, 722 Dusal, 722 Dusart's Syrup, 722 Dusting Powder, 319, 963 Dutch Drops, 256 Dyche's Compound Capsules of Guaia- col, 723 Pills of Potassium Iodid, 723 Dyeing of Leather, 1075 — with Tube Paints, 1076 Dyes, Domestic, 1073 — for Easter Eggs, 1072 Dymal, 723 Dynamyne, 723 Dysentery in Cattle, 624 Dysentery Remedies, 569, 605 — Syrup, 408 Dysmenorrhoea Drops, 51 — Mixture, 454 Dyspepsia Fermentative Tablets, 723 — in Horses, 605 — Remedies, 571 Dyspepsyn, 723 Dyspeptic Powder, 321 Dzondi's Spirit, 381 Earache Remedies, 572 Ear Medicines, 572 Easton's Syrup, 429 Easy Physic, 723 Eau Anatherine, 1014 — Celeste, 1091 -de Botot, 689 -de Botol, 1014 -de Bretfeld, 915 — de Cologne, 912 -de Fees, 723 — de Mellissede Carmes, 385 —de Quinine, 988 — Figaro, 723 — Sedative de Raspail, 532 — Vegetal, 916 Ebert's Cholera Mixture, 242 Echafolta, 723 Echinacea Compound, 737 Eching Copper, Liquid, 1078 Echino, 723 Echitone, 723 Echthol, 724 Eczema Colloid, 878 — Remedies, 573 — Remedies for Cattle, 625 — Remedies for Dogs and Cats, 649 Eczemacide, 724 Eczemarol, 724 Eczemol, 724 Edison's Polyform, 724 Eel Oil, Factitious, 254 Effervescent Powders, 320 — Powder with Magnesiax, 320 — Powder, Comp., 325 — Salts, 53, 329 Egeriol, 724 Egg-a-la-Mode, 1025 — Cocoa, 1025 — Colors, 1076 — Emulsion of Cod-Liver Oil, 724 — Soda, 1026 Eggs of Pharaoh's Serpents, 1076 — Oil of, 254 Egmol, 724 Egyptian Eye Salve, 724 — Lotus Extract, 901 — Salve, 263 Eibisch Soft, 401 Eigons, 724 Eikonogen, 724 Eisen Zucker, 215 Eka-Iodoform, 724 Ektogan, 724 Elaeossachara, 259 Elactic Collodion, 35 — Glue, 1096 Elaterin Powder Comp., 320 — ■ Trituration of, 512 Elchina, 724 Elder-Berry Syrup or Juice, 219 — Flower Extract, 901 Water, 529 — Juice of, 219 — Wine of, 537 Elecampane Camphor, 759 — Extract of, 148 Electric Headache Cures, 725 — Light Globes, to Color, 1072 Electrozone, 725 I Electuaries, 53 Electuary of Theriac, 38 Elepizone, 725 1210 INDEX. Elixirs, 53, 108 — Viburnum and Hydrastic Comp., 728 Elixir Amenorrhea, 727 — Viburnum Prunifolium Comp., 747 — Anti-Dyspeptic, 725 — Vigorans, 728 — Aphrodisiac, 725 — of Vitriol, 15 — Bromides Comp., 725 Elks' Delight, 1026 — Cascanata, 725 Ellagic Acid, 746 — Chloro-Calcium, 725 Elliman's Royal Embrocation, 728 — Chloralamid, 725 Elm, Musilage of, 248 — Chlor-Lactated Pepsin, 725 — Poultice, 314 — Creoferrate, 725 Elytrones, 728 — Digitalin Comp., 725 Embalming Fluids, 1072 — Diphthero Comp., 725 Emetis Pills, 297 — Enpnein, 725 Emoleo, 728 — Galega-Vera, 725 Emol, 728 — Guaiacol Comp., 863 Emmenagogue Powder, 317 Comp., 725 — Elixir, 76 — Halogens Comp., 725 Emetic Powder, 322 — of Heroin and Terpin Hydrate, 726 — Tincture, 460 — Heroterpine, 726 Emollient Creams, 939 — Iodide and Bromide Calcium Comp., — Ointment, 272 726 — Poultice, 314 — lodo, 726 — Species, 380 — lodo Bromide of Calcium Comp., Emollientine, 728 726 Emplastrum Calefaciens, 313 — Lactopeptine, 726 — Cantharides, 28 — Lactenzyme, 726 — Corussae, 309 — Lactopeptine with Gentian and — Fuscum, 310 Chloride of Iron, 726 — Fuscum Molle, 27 — Lactopeptine with Phosphate of '. ron, — Odontalgicum or Cephalicum, 311 Quinia and Strychnine, 726 — Vesicans, 28 — Laxative Comp., 726 Empyreumatic Oil of Juniper, 252 — Maltopepsine, 726 Empyroform, 728 — Nutrans, 726 Emulgates, 728 — Palmetto Comp., 726 Emulgen, 729 — Pancreo-Digestin, 726 Emulsifiers, 108 — Pancreo-Digestin, Gentian and Chlor- Emulsio Lini Comp., 786 id Iron, 726 — Oleosa, 110 — Pancro- Pepsin, 726 Emulsion Oil Lini Comp., 784 — Pepdilactic, 727 — Terebinthina Canadensis Comp., 742 — Pepsin and Thymol Comp., 725, r '27 Emulsions, 108-123 — Peptenzyme, 727 Emulsol, 729 — Peptopancreatine Comp., 727 Enamel Ink, 1114 — Piscidia Comp., 727 Enameled Letters, To Fasten, 1078 — Pinus Comp., 727 Endermol, 729 — Purgans, 67 Endometritis Tablets, 729 Aromatic, 727 Endorsing Ink, 1114 — Purgative, 727 Enebaer Thee, 280 — Proprietatis, 454 Enemas, 123 — Proprietatis Paracelsi, 54 Enesol, 729 — Rhei Kalinatus, 727 Euonymaus, Elixir of, 106 — Salicylic Comp., 727 — Tincture of, 509 — Saw Palmetto and Santal Comp., 727 — Extract of, 182 — Senecin and Viburnin, 727 Eno's Fruit Salt, 729 — Serenoas Comp., 721 Enterol, 729 — Six Bromides, 727 Enteronol, 729 Iodides, 727 Entozois Powder, Fluidextract, 171 — Three Chlorides, 727 Enzymol, 729 — Three Chlorides, 761 Eosin Ink, 1108 — Tonicum, 727 Eosote, 729 — Traumatic, 19 Ephredine Hydrochlorid, 729 — Uroformin Comp., 728 Epicarin, 729 — Viburnum Comp., 870 Epidermin, 730 INDEX. 1211 Epigaeae Comp., Infusion of, 210 Ethereal Extracts, 280 Epilepsy Remedies, 573 — Extract of Capsicum, 281 for Dogs and Cats, 650 — Lotion, Comp., 233 Epinephrin, 730 — Oil, 254 — Hydrate, 664 — Tinctures, 474 Epiosin, 730 Etheroles, 125 Epirenan, 730 Ethyl Bromid, 732 Epizooty Remedies, 606, 611 — Carbamate, 732, 869 Erasmus Wilson's Hair Lotion, 989 — Chlorid, 732 Ergaloids, 730 — Guaiacol, 753 Ergo Apiol, 730 — Iodid, 732 Ergone, 730 — Morphine Hydrochlorid, 720 Ergot Ammoniated, Tincture of, 474 Hydrochlorid, 732 — Aseptic, 730 — Narceine Hydrochlorid, 802 — Extract of, 148 — Salicylate, 733 — Fluidextract of, 150 — Urethane, 869 — Infusion of, 206 Ethylene Bromid, 733 — Tincture of, 474 — Ethenyl-Diamine, 790 — Wine of, 537 — Ether of Guaiacol, 754 Ergotole, 730 Ethylenediamine, 733 Ergotin, 148, 730 — Mercury Sulfate, 733 Ergotin-Styptic, 730 — Silver- Phosphate Solution, 677 Ericin, 796 — Trikresol, 733 Eriodictyon, Elixir of, 107 — Silver Phosphate, 733 — Fluidextract of, 185 Ethylglycolic Ester of Menthol, 712 Ermutin, 730 Ethylidenediethylether, 661 Erosau, 731 Eubiol, 733 Erpiol, 731 Eucaine, 733 Erweichende Kraenter, 380 — Lactate, 733 Erythroxylon, Elixir of, 73 Eucaloids, 733 — Tincture of, 469 Eucalyptene Hydrochlorid, 734 Erythrol, 731 Eucalypteol, 734 — Nitrate, 731 Eucalyptol, 734 — Tetranitrate, 731 — Gauze, 190 Erythrophleine Hydrochlorid, 731 Eucalyptus and Honey Comp., 734 Escotal, 731 — Comp., Elixir of, 76 Esencia de Calisaya, 731 Mixture, 243 -de Coca, 731 Comp., Syrup of, 408 Eserine, 731 — Elixir of, 76 — Oil, 731 — Fluidextract of, 151 — Pilocarpine, 731 — Gauze, 190 Eskay's Neuro Phosphates, 732 — Gum, Fluidextract of, 173 Eskey's Mercuricide Ointment, 732 Troches of, 516 Esmarch's Caustic Powder, 317 — Syrup of, 408 Espic Cigarettes, 732 — Tincture of, 474 Esprits, 123 Eucamul, 734 Essences, 123-124, 381, 897 Eucasin, 734 Essence Bouquet Extract, 901 Euchinin, 736 Sachet, 920 Eucodeine, 734 Pepsine, 732 Eucol, 734 Smoke, 732 Eucresyl, 734 Vera Diastase, 732 Eudermol, 734 Essentia Dulcis, 51 Eudoxin, 734 Essential Oils, 883 Euformol, 734 Ester Dermasau, 732 Eugallol, 734 Esterhazy Bouquet Extract, 901 Eugmol, 735, 887 Etching Glass, Tin and Zinc, 1078 Euquform, 735 — Iron and Steel, 1078 Eukinase, 735 Ether, Camphorated, Spirit of, 384 Eulyptol, 735 — Comp., Spirit of, 384 Eumenol, 735 — Spirit of, 384 Eumetra, 735 — Syrup of, 408 Eumydrin, 735 1212 INDEX. Eunatrol, 736 Farcy, Remedies for, 606 Eupatorium, Fluidextract of, 134 Fashion Bouquet Extract, 901 Eupeptic Hypophosphites, 736 Fat, Soap, 338 Euphorbia Pilulifera, Tincture of, 474 — Wool, 185 Euphorbium, Compound Oil of, 251 Fats, 185 Euphorin, 736 Father Kneipp's Hair Tonic, 990 Euporphin, 736 Fatty Face Powder, 959 Euphthalmine Hydrochlorid, 736 Favorite, 1026 Eupnein Elixir, 736 Fayard's Paper, 738 Eupyrine, 736 Feathers, Bleaching, 1079 Euquinine, 736 Febrile Laxative Tablets, 738 Eureka Dental Anesthetic, 736 Febrisol, 738 Euresol, 736 — Liquid, 738 — Soap, 737 Feet, Preparations for, 574 Eurobin, 737 Fehling's Solution, 350 Europhene, 737 Fehr's Compound Talcum Powder, 739 Eusemin, 737 Fel Bovis, 283 Eusocopol, 737 Felon Oil, 255 Eusoma, 737 Female Disorders, Remedies for, 574 Euthymol, 737 Fennel Comp., Tincture of, 475 — Tablets, 737 — Water, 530 Euzone, 737 Fenner's Guaiac Mixture, 454 Evaporating Lotion, 233 Fellows' Compound Syrup of Hypo- Evening Primrose Extract, 901 phosphites, 739 Exalgin, 737 Feralboid, 739 Exarysis Tablets, 738 Fercao, 739 Exhaustion Tablets, 738 Fermang, 739 Exodin, 738 Fermine Tablets, 739 Exodyne, 737 Ferrated Aloetic Pills, 291 Expectorant Mixture, 243 — Cotton, 44 Exsiccated Alum, 18 — Elixir of Cinchona, 72 Extract Jamaica Ginger, 570 Wild Cherry, 88 — of Cantharides Cerate, 28 Gentian, 78 Leeches, 738 — Extract of Apples, Tincture of, 475 ■ Red Bone Marrow, 738 of Malt, 165 Suprarenal Capsule, 738 Malt with Cod Liver Oil, 163 Extracti Olei Lenthracis, 785 — Gelsemium Comp., 739 Extraction of Flower Odors, 882 — Gelsemium Compound, 739 Extracts, Ethereal, 282 Ferratin, 739 — Liquid, 159 Ferratogen, 739 — Solid and Fluid, 125-185 Ferratose, 739 Eye Brow Pencils, 999 Ferric Chlorid, Syrup of, 418 Eye, Inflammation of, in Cattle, 626 Tincture of, 483 in Dogs and Cats, 650 — Hydrate, 214 in Horses, 606 With Magnesia, 214 in Sheep,637 — Hypophosphite, 214 of, in Swine, 643 Ferrichthol, 739 — Medicines, 573 Ferric Ichthyol, 739 Ferrier's Snuff, 337 Face and Skin Preparations, 930 Ferrinoids, 739 — Bleaches, 962 Ferrinol, 740 — Toilet Creams, 943 Ferripyrine, 740 — Powders, 958 Ferro-Mangan Dieterich, 740 Fading Inks, 1115 Ferro Manganese Peptonate, 740 False Bittersweet, Fluidextract of, 151 Ferro-Iodized Cod Liver Oil, 254 — Damiana, Fluidextract of, 151 Ferro-Salicylate, 740 — Helleboro, Fluidextract of, 128 Ferro-Somatose, 741 Fagacid, 738 Ferrocolin, 740 Family Drops, Yellow, 51 Ferrol, 740 — Salves, 586 Ferroleum, 740 Fancy Lemonade, 1026 Ferrous Carbonate Pills, 298 Fantasma Nog, 1026 Saccharated, 213 INDEX. 1213 — Chlorid, Solution of, 356 Flower Extract, 907 Syrup of, 418 — Food, 1087 — Iodide, Saccharated, 215 — Coloring of, 1087 — Syrup of, 418 — Odors Extraction, 882 Ferrophosphated Elixir of Gentian, 78 Flowers of Erin, 902 Ferropyrine, 740 Ireland Extract, 902 Ferrostyptixi, 741 — — Seville Extract, 902 Ferruginous Pills, 298 # Fluid Belladonna Plaster, 34 Ferrum Acetate, Solution of, 350 — Culture, 45 — Sanguine's, 741 Fluidextracts, 186 Fersan, 741 Fluid Hydrastis, 743 Fertilizers, 1079 —Lightning, 581, 743 Festoform, 741 — Magnesia, 365 Fetrone, 741 — Nutrient, 45 Fever Medicines for Cattle, '626 — Transfusion, 512 for Horses, 606 Fluoroformol, 743 — Tree, Tincture of, 474 Fluoroform Water, 743 Fibrolysin, 741 Fluorol, 743 Field Flowers Sachet, 921 Fluoryl, 743 Fikulax, 741 Fluorrheumin, 743 Filhos' Caustic, 27 Fly Exterminators, 1087 Filmaron Oil, 742 — Lime, 1087 Filmogen, 742 — Paper, 1087 Filter Paper, Toughened, 1079 — Pastilles, 1088 Finger-Nail Cosmetics, 1021 — Pencils, 1088 Fir, Inhalation of, 211 — Powders, 1088 Fire Extinguishers, 1082 — Preventives, 1089 Fireproofiinsr Fabrics, Wood, Paper, Foin Coupe, 887 etc., 1083 Foot Lotion, 1020 Fires, Colored, 1080 — Powders, 1019 Fireworks Papers, 1082 — Preparation, 1019 Firolyptol, 742 — Preparations, 1016 Firwein, 742 — Rot, Remedies for, 626 Fitch's Kidney and Liver Cooler, 742 in Sheep, 637 Fitchmul, 742 Foote's Formula, 985 Fits in Dogs and Cats, 650 Forbe's Emulsion of Oil of Turpentine, Fixing Bath, 1084 122 Flagg's Relief, 742 For "Cold Sores," 972 Flaunders' Diffusible Tonic, 742 Forget-Me-Not Extract, 902 Flannel, Canton, Absorbent, 186 Formacoll, 743 Flash Light Powders, 1084 Formalbumin, 743 Flavoring No. 29, Elixir of, 76 Formaldehyde, 743 — No. 508, Elixir of, 76 — Acetamide, 744 Flavorone, 742 — Casein, 743 Flaxseed, Infusion of, 207 — Mouth Wash, 1014 ' — Poultice, 314 Formalin, 743 Flea Exterminators, 1084 — Gelatin, 743, 749 — Powder, 650 Formane, 743 Fleming's Tincture of Aconite, 453 Formamine, 743 Fleur de Lys Extract, 902 — Compound Tablets, 743 Flexible Collodion, 35 Formamint, 743 Flies, Treatment for, 607 Formasal, 744 Flint's Saline and Chalybeate Tonic, 742 Formaseptol, 744 Flon's Lenitive Syrup, 742 Formatone, 744 Floor Polish, 1086 Formenthol, 744 — Wax, 1085 Formetto Capsules, 744 — Oils, 1085 Formidine, 744 Flora China, 742 Formin, 744, 838 Floral Jewel Extract, 902 Form in e, 744 Floricin, 742 Formicine, 744 Florida Water, 915 Formochlorol, 744 — Lotus Extract, 902 Formol, 743 1214 INDEX. Formolid, 744 Formolyptol, 688 For Red Hands, 972 Fortoine, 745 Fosgate's Anodyne Cordial, 745 Fossilin, 745 Fothergill's Antidyspeptic Pills, 293 — Cough Mixture, 567 Founder in Cattle, 626 Founder in Swine, 643 — Remedies for, 607 Four Chlorids, Elixir of, 68 Fournier's Wine of Creosote, 745 Fowler's Solution, 372 Foxglove, Tincture of, 473 Fox Lungs, Syrup of, 408 Fructose, 718 Franck's Grains de Sante, 745 Frangipanni (Roman) Extract, 902 — Extract, 902 — Sachet, 921 _ Frangula, Elixir of, 65 — Extract of, 135 — Fluidextract of, 135 — Tincture of, 461 Franzoser Salbe, 261 Freckle Removers, 968 Freezing Mixtures, 1089 Freligh's Remedy, 745 — Tonic, 745 French Mixture, 353 — Varnish, 1181 Fresh Drugs, Tincture of, 475 — Herbs, Tincture of, 475 Frey's Vermifuge, 745 Friar's Balsam, 19, 458 Fringe Tree Alterative, 745 Frosted Coffee, 1026 — Chocolate, 1026 Frosting Windows, 10£9 Frostwort. Fluidextract of, 151 Frozen Cream, 1026 Fruit Stains, to Remove, 1090 — Cream, 1031 — Lemonade, 1026 — Malt, 1026 — Nectar, 1026 — Shrub, 1027 Fruneau's Antiasthmatic Paper, 745 Fuchs-Lunger Saft, 408 Fucus. Vericulosus, Fluidextract of, 133 Fuller's Earth Nursery Powder, 966 Fumigating Essence or Tinctures, 930 — Paper, 930 — Pastilles, 928 — Powder or Species, 929 — Preparations, 928 Fungicides for Plants, 1090 Furniture Polishes, 1093 — Varnish, 1181 Furs, Preserving, 1092 Furunculin, 745 Gadberry's Mixture, 246 Gadberry's Mixture, 745 Gaduol, 745 Gaiacophosphal, 746 Galangal, Fluidextract of, 151 Galbanum Comp. Pills, 297 — Plaster, 307 — Plaster Comp., 307 — Plaster, Red, 307 Gallonol, 746 Gallic Acid Anilide, 746 Glycerite of, 198 Ointment, 265 Galliein, 746 Gallinol, 746 Gallobromol, 746 Gallogen, 746 Gall Ointment, 270 Galls, Aromatic, Elixir of, 76 — in Horses, 608 — Tincture of, 490 Gambir Comp., Tincture of, 475 — Troches of, 516 Gamboge Comp. Pills, 297 Capes in Pheasants, 657 Garantose, 746 Gardner's Syrup of Hydriodic Acid, 746 Hypophosphite of Ammonium, 746 fare's Lecithine, 746 Gargles, 575, 590 Gargle. Borax, Mackenzie's, 186 Garlic, Svrup of, 409 Artificial, 409 Garus, Elixir, 76 Gas Burner Cement, 1057 Gasoline Jelly, 1094 Gasterin, 746 Gasterine, 746 Gaulsalol Capsules, 747 Gaultherine, 747 Gauzes, 186-194 Gav's Diarrhea Tablet, 569 G. D. D. Liniment, 227 Gelanthum, 194, 747 Gelasepsin, 747 Gelatina Lichenia Islandica, 195 Gelantinized Benzin, 1040 Gelatins, 195 — Medicated, Unna's, 195 Gelatol 747 Gelatole Emulsion of Zinc Oxid, 196 Gelatose-Silver, 665, 747 Gelbe Quicksilber Salbe, 268 Gelin's Granules of Arseniate of Gold, 747 Gelis & Conute's Dragees of Lactate of Iron, 747 Gelone, 747 Gelseminine. 747 Gelsemium, Fluidextract of. 151 — - Tincture of, 475 INDEX. 1215 Genitone, 747 Glonoin, 748 Gentiana Quinquefolia Fluidextract of. — Pills, 297 152 — Spirit of, 385 Gentian and Iron Phosphate, Elixir of, — Tincture of, 477 78 Glossy Inks, 1108 Pyrophosphate, Elixir of, 78 Glove Cleaners, 1094 Phosphorus, Elixir of, 78 — Perfume, 925 — — Tinct. Iron Chlorid, Elixir of, 78 Glucose, Syrup of, 409 — Cinchona and Iron Malate, Elixir of, Glue, Bookbinders, 1095 77 — Liquid, 1095 — Comp., Elixir of, 77 — Marine, 1096 Fluidextract of, 152 — Stick, 1096 Infusion of, 206 — Waterproof, 1096 — — Stronger Infusion of, 206 — Zinc, 196 Tincture of, 476 Gluside, 748 — Elixir of, 77 — Elixir of, 99 — Extract of, 151 Glutannol, 748 _ — Ferrated, Elixir of, 78 Gluten Suppositories, 749 — Fluidextract of, 151 Glutiform, 748 — Glycerinated, Elixir of, 78 Glutol, 749 — Mixture, Alkaline, 243 Gluton, 749 — Tincture of, 476 Glycamyl, 201 Geranium Comp., Infusion of, 207 Glycerates, 196 — Fluidextract of, 152 Glycerin and Honev Jelly, 953 — Water, 915 — Balsam, 939 Gerdal, 748 — Cold Cream, 937 German Bird Paste, 656 — Camphor Ice, 954 — Cathartic Salt, 748 — Emollient, 749 Germicidal Discs, 748 — Honey, 953 Germicide Solutions, 351 — Jelly, 952 Geronil, 887 — Lotion, 232, 951 Geoline, 747 - — Ointment, 201 George's Pectoral Paste, 747 — Salicylate, 751 Geosote, 748 — Suppositories, 397^ G. E. Solium Salicylate Comp., 665 Glycerinated Gelatin^ 394 Gessner's Lotion, 985 — Zinc Gelatin, 195 — Ointment, 985 Glycerinum Pepticum, 749 Gewuergnafte Kraeuter, 379 Glycerite of Boric Acid, 23 Gilbert's Syrup, 425 Styrolene, 749 Gicht Watte, 41 Glycerites, 196-202 Giles' Iodide of Ammonia Liniment, 748 Glycerogelatins, 202 Gilt Edge Butter Compound, 748 Glycerole Heroin Comp., 749 Ginger Bouquet, 1027 — of Celery Compound, 749 — Fluidextract of, 152 — ■ — 'Glycerophosphates Comp., 751 — Oleoresin, 281 Lecithin, 749 — Soluble, Essence of, 123 Lecithine, 749 Tincture-of, 123 — Pepsin and Wafer Ash, 749 — Solution of, 123 — -Jerbine Compound, 750 — Syrup of, 409 Glyceroles, 196 — Tincture of, 476 Glycerophosphates, 750 — Troches of, 516 — Comp., 750 — Wine Toddy, 1027 Syrup of, 409 Girard Laxative Pills, 748 — Elixir of, 78 —Uterine Tonic, 748 — • Syrup, 750 Glacialin, 748 Glycerophosphoids. 750 Gladness, Oil of, 255 Glyceryl Borate, 23 Glanders, Remedies for, 608 Glyceritum Ichthyolis Comp.. 1 70 Glass Labels, Cement for, 1057 Glyceryl Borate, Glycerite of. 197 Glassware Cement, 1057 Glyco-Chlorides, 750 Gleet, Remedies for, 575 Glyco-Gelatin Pastilles, 288 Glidin, 748 Glycogen, 750 Globules, Homeopathic, 196 Glycomorrhum, 751 1216 INDEX. Glycones, 751 Glyconin, 751 Glycosal, 751 Glyco-Thymoline, 751 Glycotin Comp., 751 Glycotone Comp., Capsules, 751 Glyco-Vitae, 751 Glycyrrhigin, Ammoniated, Syrup of, 409 — Aromatis, Elixir of, 78 — Elixir of, 78 Glvkaolin, 751 Glvmol, 751 Glyphocal, 751 Gynecol Ointment, 756 Gvnocardia Ointment, 263 Gnat Oil, 609 Goddard's Cosmetic Lotion, 963 Godfrey's Cordial, 246, 751 Gold and Arsenic Bromids, Solution of, 351 Iodid, Solution of, 351 — Drops, 51 — Ink, 1108 — Monobromid, 751 — Tarnished, to Restore, 1096 — Tropfen or Tinktur, 51 Golden Buck,_ 1027 — Hair Coloring, 996 — Rod, Tincture of, 477 — Seal and Aconite Lotion, 233 Comp., Infusion of, 207 Lotion, 233 Tincture of, 477 Wine of, 537 Extract of, 152 Fluidextract of, 152 Fluidextract of, Colorless, 153 Fluidextract of Equeous or Non- Alcoholic, 152 Glvcerite of, 198 Powder, Comp., 320 — Tincture, 51, 477 Goldthread, Fluidextract of, 153 Goldware, To Clean, 1096 Gondrat's Ointment, 259 Gonorrhea Remedies, 575 Gonosan, 751 Good Samaritan Oil, 751 Goodell's Pills, 303 Goose Oil, 254 Gorite, 751 Goss' Anticonstipation Pills, 292 — Improved Laxative Pills, 752 Gossypium Purificatum, 39 Goudrogenin, 752 Goulard's Cerates, 28 — Extract, 364 — Lotion, 364 Gourand's Oriental Cream, 752 Gout Remedies, 577, 585 Goutline, 752 Gowland's Cosmetic Lotion, 963 Grafting Wax, 1096 Grains de Sante, 745 Graminin, 752 Grana Angelica, 671 Granatum, Decoction of, 47 Granola, 1027 Granulas, 202 Granulated Opium, 282 Granville's Counter-irritant Lotion, 225 Grape-Ade, 1027 — Cooler, 1027 — Cup, 1027 — Egg Phosphate, 1027 — Glace, 1027 — Lemonade, 1027 — Orange, 1027 — Sherbet, 1027 Grapiol, 752 Gray Oil, 255 — Ointment, 261 — Powder, 238 Gray's Specific Pills, 752 Grease Eradicators, 1097 — Paints, 962 — Proof Boxes, 1097 — Remedies for 609 Greases, 203 Greasy Bottles, to Clean, 1097 Grecian Varnish, 1181 Green Cerate, 28 — Hellebore, Fluidextract of, 182 Tincture of, 508 — Inks, 1108 — ■ Mountain Kidnev Cure, 752 Oil, 752 Salve, 752 — Oil, 255 — Ointment, 265 — Salve, 305 — Soap, 338 Comp. Tincture of, 477 -Tincture of, 230, 477 — Tinctures, 475 — Varnish for Metal, 1181 — Wonder Oil, 225 Greenhow's Cholera Mixture, 242, 752 Gregory's Powder, 324 Grenades, Fire, 1097 Griffith's Compound Mixture of Guaiac, etc., 753 — Guaiac Mixture, 454 — Pills, 299 Grillon's Tamar Indien, 753 Grimault's Matico Injection, 753 — Paullinia Powders, 753 — Syrup of Bark and Iron, 753 Geindelia. Elixir of, 79 — Aromatic, Elixir of, 79 — Fluidextract Alkaline, 153 — Fluidextract of, 153 Gripes, Medicines for, 609 Grippe, Remedies for, 553 Griserin, 753 INDEX. 1217 Groen 01 je, 256 Gross's Hair Lotion, 989 Ground Glass, Imitation, 1097 Guaiac, Ammoniated, Tincture of, 477 — Aromatic, Tincture of, 478 — Cornp., Tincture of, 478 — Elixir of, 79 — Fluidextract of, 153 — Gargle, 590 — Glycerite of, 198 — Resin, Troches of, 516 — Syrup of, 410 — Tincture of, 477 Guacamphol, 753 Guaethol, 753 Guaiacetin, 753 Guaiacol, 753 — Albuminate, 753 — Albuminate, 763 — Benzoate, 683 — Camphorate, 753 — Carbonate, 722 — Carbonate, 753 — Carbonate Comp., 753 — Cinnamate, 753 — Ethylene, 754 — Co. Elixir, 753 Guaiacolghycerylester, 754 Guaiacoline, 754 Guaiacol Phosphal, 754 — Phosphate, 746 — Phosphite, 754 — Piperidin, 754 — Salicylate, 754 — Salol, 754 — Somatose, 754 — Valerianate, 748, 754 Guaiacyl, 754 Guaiaform, 754 Guaialin, 754 Guaiamar, 754 Guaiaperol, 755 Guaiaquin, 755 Guaiasanol, 755 Guaisotol, 755 Guaiatonic, 755 Guajasanol, 755 Guano, Artificial, 1097 Guarana, Elixir of, 79 — Fluidextract of, 154 Guatannol, 755 Guatanuin, 755 Guayarsin, 755 Guilliermond's Sirop Iodotannique, 755 Guindre's Sal Aperiens, 755 Gum, Arabic Mucilage of, 247 Gummi Pflaster, 309 Gummosus, Syrup, 400 Gun Barrels, 1097 — Powder, 320 — Power White, 320 Gunther's Sedative Pills, 755 Gurmin, 755 Guttae, 50 — ad Menstrua Tarmentosa, 51 Gutta Jesuitarum, 52 — Percha Cement, 1057 Purified, 1097 Solution of, 351 Haarlem Balsam, 256 — Oil, 256, 756 Haas' Hog Cholera Remedy, 756 Hseman, 756 Hsemo-Cardiacin, 756 — Mangan, 757 — Neuralin, 757 Haemoform, 756 Haemoglobin, 757 Haemoglobogen, 757 Haemol, 756 Haemolin, 757 Haemoantitoxin, 756 Hsematogen, 756 Hsemoferrum, 756 Hsemol, 760 Hsemostyptic, 757 Hsemostatin, 757 Hsemostasin, 757 Haematoprotagon, 757 Hagan's Magnolia Balm, 757 Hagee's Cordial of the Extract of Cod Liver Oil Comp., 757 Hagenia, Infusion of, 207 Hager's Catarrh Pills, 294 Haggard's Stool Promoter, 757 Hahnemann's Soluble Mercury, 238 Hair-Color Restorers, 990 — Curling Liquid, 983 — Drying Powders, 978 — Dye in Ointment Form, 996 — Dyes, 991 — Gloss, 991 — Loss of, for, 986 — Oils, 978 — Pomades, 980 — Pomatums, 980 — ■ Preparations for, 973 — Removers, 1000 — Tonics, 987 — Tonic Containing Oil, 988 Containing Resorcin, 988 Hall's Hair Renewer, 757 Haller's Acid Mixture, 246 Hall's Solution of Strychnine, 376 Halogens Compound Elixir, 758 Hamamelis Ointment, 275 — Tincture of, 510 Hamburg Plaster, 758 Hamlins' Cholera Mixture, 242 Hammond's Tonic, 511 Hampton's Vital Restorer, 758 Hand Cleaners, 963 — Grenades, 1082 Hankerchief Extracts. 894. POO Hands, To Remove Stains from, 1098 1218 INDEX. Hand Whiteners, 963 Hard Soap, 338 Hardy's Ointment, 758 Hare's Elixir, 58 Harlan's Tooth Paste, 1010 Harness Blacking, 1008 — Dressing, 1008 — Makers' Wax, 100R — Oil, 1098 — Varnish, 1098 Harntreibender Thee, 379 Harney's Cholera Mixture, 242 Hartman's Crimson Salt, 758 Hartshorne's Cough Mixture, 567 Harvest Queen Extract, 903 Haskell's Enteritis Tablets, 758 Hasty Pudding, 1028 Hat^ to Clean, 1098 Hawthorn Blossom Extract. 903 Hayden's Uric Solvent, 758 — Viburnum Compound, 758 Hayes, Acid Hypophosphites, 758 Hay Fever Remedies, 577 Hazeline, 757 Headache Cologne, 914 — Remedies, 577 Headine, 758 Healing Ointment, 265 — Salve, 586 Health, Elixir of, 501 — Salt, 334, 853 Heart- Strengthening Drops, 51 — Stroke, 588 Heave Medicines, 609 Heavenly Twins, 1028 Hebra's Arsenic Pills, 293 — Cosmetic Liniment, 973 — Itch Ointment, 273 — Oriental Cosmetic Water, 962 Hecto-Pepsin, 758 Hectograph Pads, 1099 — Inks, 1111 — Sheets, 1100 Hedeoma, Tincture of, 495 Hedonal, 758 Heel Ball, 1099 Heels, for Cracked, 610 Heft Pflaster, 312 Helcosol, 758 Helenin, 759 Helenii, Extractum, 148 Helfin, 759 Helgotan Bromate, 759 Helianthemum, Fluidextract of, 151 Helianthus Comp., Syrup of, 410 — Svrup of. 410 Heliotrope, 925 — Extract, 903 — (White) Extract. 903 — Sachet, 921 Heliotropin, 888 Hellebore Comp., Wine of, 537 — Green, Tincture of, 508 Helinbold's Extract Buchu, 759 Helmitol, 759 Helonias Comp., Elixir of, 79 — Cordial, 79 — Elixir of, 79 Helonia Tablets, 759 Helomias Cordial, 759 Helthin, 759 Hemapeptone, 759 Hematic Hypophosphites, 759 Hematothyroidine, 760 Hematoxylin, 760 Hematysin, 760 Hemec Tablets, 760 Hemicranin, 760 Hemidesmus, Svrup of, 410 Heminal, 760 Hemisine, 760_ Hemlock, Fluidextract of, 145 — Juice of, 218 — Ointment, 263 — Plaster, 306 — Poultice, 314 — > Spruce, Extract of, 154 — ■ — Tincture of, 478 — Tincture of, 471 Hemoboloids, 759 Hemoglobin, 760 Hemogallol, 760 Hemol, 760 — Arsenated, 760 — Bromid, 692 — Cuprated, 760 — Iodized^ 760 Hemonervine, 760 Hemoquinine, 761 Hemorrhoidic Pills, 761 Hemostatin, 761 Hemostatic Cotton, 44 Henbane, Extract of, 154 — Fluidextract of, 154 — Green, Extract of, 154 — Infused, Oil of, 256 — Tincture of, 478 — Comp., Oil of, 256 — Juice of, 219 — Comp., Pills, 297 Henna Hair Dve, 995 Henry's Carbolic Salve, 761 — Cosmetic, 761 — Magnesia, 761 — Three Chlorides, 761 — Tri-Iodides, 761 Hensel's Tonic, 511 — Tonicum, 761 Hepar Sulfur, 24 — Sulfuris, 313 Heparon, 761 Hepatosmene, 761 Herculine, 1028 Hermophenyl, 761 Heroids, 761 Heroin, 762 INDEX. 1219 Heroin Hydrochloric!, 762 — Balsam of, 19 Heroline, 762 — of Hoarhound and Tar, 566 Heromal, 762 Honeymoon Extract, 903 Herophosphites, 762 Honeysuckle Extract, 903 Heroterpine, Elixir, 762 Honey Water, 915 Herpicide, 762 Honthin, 765 Hesperis Extract, 903 Hoofs, Preparations for, 610 Herpetic Wash, 233 Hooper's Female Pills, 765 Herzstaerkungs Troffen, 51 — Pills, 297 Hetocresol, 762 Hop Bitters, 765 Hetoform, 762 Hope's Camphor Mixture, 239 Hetol, 762 Hopogan, 765 — Caffeine. 762 Hops, Elixir of, 79 Hetralin, 763 — Fluidextract of, 154 Hexamethylenamine, 763 — Infusion of, 207 Hexamethylenetetramine, 763 — Tincture of, 480 Hexamethylenamine Methvlenecitrate, Horehound Comoound, Fluidextract of, 759 155 — Methvlenecitrate, 763 — Compound Syrup of, 411 Hexenschuss Pflaster, 309 Horlick's Infant's Food, 765 H. H. H. Medicine, 756 Horn, to Color Black, 1101 Hienfong Essence, 763 Horner's Rheumatic Lightning, 765 Hiera Picra, 316 Horse Medicines, 597 Hinckle's Comp., Cascara Pills, 294 Horseradish Comp., Spirit of, 384 Hippol, 763 Syrup of, 411 Hips, Tincture of. 478 — Tincture of, 480 Hirudin, 763 Horsford's Acid Phosphate, 765 Histogenol, 763 Hostelley's Wine of Cod Liver Oil, 766 Histosan, 763 Hot Drops, 52, 462 Hitt's Headache Powder, 764 Hoven, Remedies for, 627 Hive Syrup, 437 Howe's Damiana Tablets, 766 Hives, Remedies for, 578 — Kidney Tablets, 766 Hjerne's Testament Drops, 91 Hoyt's Hiawatha Hair Restorative, 766 Hjertestyrkende Draaber, 51 Hudson's Honey of Elm, 766 H.—M.—C, 764 Huiles Philocome, 978 Hobb's Kerosene Liniment, 764 Hufeland's Infant Powder, 320 Hoffmann's Anodyne, 384 Huckleberrey Juice, 219 Hoffmann's. Balsam of Life, 245 Hufeland's Nerve Tea, 766 — Drops, 52, 384 Humanized Milk Powder, 322 — Drops, Red, 52 Hummerfelds Cosmetic Water, 973 — Stomach Elixir, 92 Hungarian Mustache Pomade, 998 Hog Cholera Remedies, 644 — Mustache Wax, 998 Hog's Bread, Tincture of, 473 Hungary Water, 915 Hokey-Pokey Glace, 1028 Hunn's^ Drops, 239 Hollyhock Confection, 37 with Chloroform, 766 Holodin, 764 Hunter's Red Drops, 52, 766 Holloway's Ointment, 764 Hunter's (John) Tooth Powder, 1005 — Pills, 764 Husband's Magnesia, 766 Holman's Liver Pad, 764 Huxley's Menthol and Wintergreen Holocaine Hydrachlorid, 764 Cream 766 Holy Bitter, 316 Hyacinth Extract, 904 Holzinol, 765 Hydracerin, 767 Holz Thee, 381 Hydracetin, 766 Homatropine Hydrobromate, 765 Hydrocine, 768 Homeopathic Medications, 237 Hydrocyanate of Iron, 768 — Powders, 320 Hydragogin, 766 — Solution, 352 Hydragogue Tincture. 537 — Tinctures, 478 Hydrangea, Fluidextract of, 155 — Triturations, 513 Hyararg-Iodo-Nucleoid, 767 Hommel's Haematozen, 765 Hydrary-Nueleoid, 767 Honey, 203 Hydrara:vrin, 767 — and Almond Cream, 948 Hydrargyrol, 767 Tolu, 566 Hydrargyne, 767 77 1220 INDEX. Hydrastin, 204 — of Iron and Quinine, 80 Hydrastine, 767 Elixir of, 83 — Hydrochlorid, 767 Quinine and Strychnine, Hydrastis and Calisaya Tonic, 767 Elixir of, 81 — Colorless Solution of, 352 Sodium, Elixir of, 81 — Extract of, 152 — Solution of, 353 — Glycerite of, 198 — With Malt Elixir of, 81 — Powder Comp., 320 Iron, Elixir of, 80 — Tincture of, 477 Iron Syrup of, 414 Hydrastoids, 767 Tar, Elixir of, 81 Hydrate of Iron, 214 — Solutions, 769 With Magnesia, 214 — Syrup of, 411 Hvdrated Bismuth Oxid, 21 Hypophospholoid, 769 — Oil, 768 Hvpophosphorous Acid, 113 Hydriodic Acid Solution of, 352 Dilute, 14 Syrup of, 411 Hvrgol, 768 — Ether, 732 Hysterol, 769 — Ether, 767 — Acid, Dilute, 12 Iatrevin, 769 — Ether, 732, 767 Ibit, 769 Hydrochinone, 767 Ice Cream Sandwiches, 1028 Hydrochloric Acid, Dilute, 12 Shake, 1028 Hvdrocvanic Acid, Dilute, 12 Iceland Moss, Gelatin, 195 Inhalation of, 211 Decoction of, 46 Solution of, 353 Jellv, 195 Ointment, 265 Ichthalbin, 770 Hydrogol, 768 Ichthanimon, 770 Hydrographic Paper, 1101 Ichthargan, 770 Hydroleine, 768 Ichtermol, 770 Hvdronal, 768 Ichthyol, 770 Hydromel, 204 — Albrimante, 770 Hvdroquinone, 767 — Calcium, 771 Hydrosol, 768 — Cotton, 42 Hvdroxvlamine Hvdrochlorid, 768 — Deodorization and Disguising Taste Hydrozen, 768 of, 204 Hygrometer Paper, 1037 — Formaldehyde, 770 Hvmosa, 768 — Ointment, 265 Hyos-Sco-Phine, 768 Comp. or Salicvlated, 265 Hyoscine Hydrobromate, 768 — Paste, Unnas, 287 — Morphine and Cactin Comp., 768 — ■ Piperazine, 771 Hyoscyamine, 768 — Salicyl, 771 Hyoscyamus, Extract of, 154 — Sodium, 771 — Fluidextract of, 154 Ichtholdine, 770 — Tincture of, 478 Ichtholferrin, 770 Hyper-Samphire, 768 Ichthyolodin, 771 Hypodermic Injections, 204, 211 Ichthyolum Anstriacum, 771 Hyperici, Tincture of, 504 Ichthvalum Ointment, 770 Hyperphosphine, 766 Ichthyomenthol, 771 Hypnal, 769 Idiaton, 771 Hypno-Bromic Compound, 769 Idlewild, 1028 Hypnoacetin, 769 Ignatia, Tincture of, 480 Hypnone, 769 Immerwaehrendes Spanischflieger Hypnopyrine, 769 Pflaster, 306 Hypo-Quinidol Pills, 766 Imperatrice Extract, 903 Hypodermic Syringes, to Clean, 1101 Imperial Pills, 298 Hypophosphites Comp., Elixir of, 80 Improved Vegetable Cathartic Pills, 294 ■ Solution of, 353 Incense, 1102 Svrup of, 412 Indelible Inks, 1112 Wine of, 538 Independence Tonic, 1028 — Elixir of, 80 Indestructible Ink, 1115 — Glycerite of, 198 India Ink, 1115 — Hayes' Acid, 769 Indian Hemp, Tincture of, 463 Hypophosphite of Iron, 214 — Meal Poultice, 314 INDEX. 1221 Indigestion in Cattle, 627 Horses, 611 — Remedies, 571 Indian Sarsaparilla, Syrup of, 410 Indoform, 771 Infant's Diarrhea Mixture, 570 Infant Powder, 320 — Powders, 963 — Sedative Alkaline, 771 Influenza Remedies for Horses, 611 Influenzine, 772 Infused Oils, 256 Infusions, 204 Infusion of Roses, Acid, 208 Ingestol, 772 Inghurin, 772 Inhalations, 210, 211 Injectio Amylopsini, 772 — Trypsini, 772 Injections, 123, 211 Injection Hirsch, 772 Injection of Ergot, Hypodermic, 212 Inks, 1102 Ink Erasing Pencil, 1123 — Erasives, 1122 — for Blue Paper, 1111 Celluloid, 1119 Silver Prints, 1111 — Powders, 1120 — Stains, to Remove, 1123 Insect Bites and Stings, 627 — Destroyers, 112^ — Powders, 1124 Insects, Attacks of, on Sheep, 638 — in Books, to Prevent, 1125 — in Drugs, 1125 Insecticides for Plants, 1125 Intensifying Solutions, 1128 Intestin, 772 Inula Camphor, 759 Invisible Inks, 1115 Iodalbacid, 772 Iodalbin, 772 Iodalgine, 772 Iodalia, 772 Iodamyl, 772 Iodan, 772 Iodantipyrin, 775 Iodferratose, 772 Iodia, 772 Iodic Acid, 773 Iodid of Iron, Saccharated, 215 Potassium, Elixir of, 81 Starch, 390 Sulfur, 391 Iodin, Carbolized, Solution of, 353 — Caustic, Lugol's Solution of, 353 Solution of, 353 — Churchill's Tincture of, 481 — Comp., Glycerite of, 198 Solution of, 353 Tincture of, 481 — Decolorized, Tincture of, 481 — Ethereal, Inhalation of, 211 — Ethereal, Tincture of, 482 — Eugmol, 773 — Glycerole of, 198 — Inhalation of, 211 — Liniment, 227 — Mild Solution of, Lugol's, 354 — Ointment, 265 Comp., 265 — Pills, 298 — Rubefacient, Solution of, Lugol's, 354 — Solution, Magendie's, 354 — Tincture of, 481 Iodinol, 773 Iodipin, 773 Iodized Carbolic Acid, 12 — Collodion, 35 — Cotton, 42 — Emulsion, 773 — Hemol, 774 — Oil, 257 — Phenol, 12 — Sesame Oil, 773 — Starch, 773 Iodlecithin, 773 Iodoamisol, 773 Iodo-Bromid of Calcium Comp., Elixir of, 81 — Eigon, 773 — Eigon Wine, 774 ■ Sodium, 774 — Eugenol, 774 — Hemol, 774 — Mangan, 774 — Mildine, 775 — Nucleoid, 775 Iodochloroxyquinolin, 873 Iodocol, 773 Iodocrol, 773 Iodofan, 774 Iodoform, 482 — Albuminate, 774 ■ — Aromatic or Deodorized, 212 — Collodion, 35 — Cotton, 42 — Gauze, 190 — Glycerogelatin of, 202 — Jute, 220 — Ointment, 265 — Powder Comp., 321 — Removing Odor of, 1129 — Suppositories, 398 — Suppositories, Urethral, 398 Iodoformal, 774 Iodoformin, 774 Iodoformogen, 774 Iodogallicin, 774 Iodoglobin, 774 Iodol, 774 — Collodion, 35 — Cotton, 43 — Gauze, 192 1222 INDEX. Iodophene, 775 Iodo-Phenique Syrup of, 415 Iodophenochloral, 775 Idophenol, Syrup of, 415 Iodopyrin, 775 Iodose, 775 Iodosol, 775 Iodosyl, 775 Iodotannated Syrup, 415 Iothion, 776 Iodothyrine, 775 Iodozen, 775 Iodvloform, 776 Ionarol, 888 Ionone, 888 Ipecac, Acetic, Syrup of, 416 — and Morphine, Troches of, 517 Opium, Syrup of, 416 Opium Powder, 321 Tincture of, 482 Squill, Pills, 298 ■ — Fluidextract of, 155 — Liniment of, 227 — Ointment of, 266 — Svrup of, 415 — Tincture of, 482 — Troches of, 516 — Vinegar of, 522 — Wine of, 538 Iridir, 212 Iris, Extract of, 133 ■ — Tincture of, 461 Irish Moss Comp., Syrup of, 416 Gelatin, 195 Irisol, 776 Iron Acetate, Etheral, Tincture of, 483 ■ Howe's, Solution of, 354 ■ Solution of, 354 . Tincture of, 482 — Albuminate, Elixir of, 81 — Albuminate, Solution, 340, 354 Syrup of, 416 — Albumose, 741 — and Ammonium Acetate, Solution of, 355 Citrate, Solution of, 356 Phosphate, Syrup of, 416 Valerianate, Elixir of, 82 Arsenic, Bitter, Elixir of. 82 Manganese Iodid, Syrup of, 420 Maganese Saccharate, Solution of, 359 Potassium Tartrate, Wine of, 539 Quinine Citrate, Effervescent Salt, 332 Citrate, Elixir of. 87 Solution of. 362 Wine of, 539 Comn. Pills., 302 Todids. Syrup of. 421 Sodium Albuminate. Svrup of. 416 Wild Cherry, Elixir of, 88 — Arsenate. Syrup of. 417 — Arsenic and Mercury, Chlorids, Elixir of, 68 Strvchnine, Elixir of, 82 — Bitter, Wine of, 539 — Bromid, Syrup of, 417 — Bromid, With Quinine, Syrup of, 418 and Strvchnine, Syrup of, 418 — Carbonate, Mass of, 236 Pills, 298 Saccharated, 213 — Cement for. 1057 — Chlorid (Ferrous) Syrup of, 418 Glycerite of, 198 Solution of, 365 Suppositories, Urethral, 398 Ethereal, Tincture of, 483 Toluenated, Tincture of, 484 With Menthol, Tincture of, 44 — Citrate, Effervescent Salt, 332 Wine of, 539 With Magnesia, Effervescent Sal + . 332 — Citro-Chlorid, Tincture of. 484 — Compounds. 212-217 — Comp., Pills, 299 Tincture of, 484 — Crude Malate of, 129 — (Ferric) Chloral, Tincture of, 483 — Ferrocyanid Pills, 299 — (Ferrous) Carbonate Trituration, 513 — Gargle, 590 — Glycerophosphate, 776 — Hair Dyes, 994 — Hypophosphite, Elixir of, 83 Solution of, 357 Svrup of, 414, 418 — Ichthyol, 770 — Iodid (Ferrous) Syrup of, 418 — Iodid Pills, 299 Solution of, 359 Tasteless, Syrup of, 419 — Jelloids, 776 — Lactate, Elixir of, 83 — Lactophosphate, Svrup of, 419 — Nitrate Solution of, 359 — Oxychlorid, Solution of, 360 — Paranucleinate, 864 — Pepsin and Quinine, Elixir of. 83 — Peptonate Elixir, 83 Solution of, 360 With Maganese, Solution of, 361 — Phosphate. Cinchonidine and Strych- nine, Elixir of, 84 Comp., Svrup of, 421 Effervescent Salt, 332 Elixir of. 84 — — (Ferrous) Syrup of. 421 Quinine and Strvchnine. 84 Solution of. 362 — Pills. 298 — Plaster, 307 — Promated, Tincture of. 484 INDEX. 1223 — Protochlorid, Syrup of, 421 — Protoxide, Solution of, 362 — Pyrophosphate and Quinine, Elixir of, 86 — Pyrophosphate and Strychnine, Elixir of, 86 Effervescent Salt, 333 Quinine and Strychnine, Elixir of, 86 Solution of, 362 Syrup of, 421 — Quinine and Arsenic, Elixir of, 87 Strychnine, Elixir of, 87 Phosphates, Elixir of, 87 Phosphates, Syrup of, 421 — Reduced Troches of, 517 — Salicylate, Elixir of, 88 Comp., Elixir of, 88 Solution of, 363, 373 — (Soluble) Oxid, Syrup of, 420 — Somatose, 741 — Subsulf ate, Solution of, 363 — Succinate, 776 — Sulfate, Solution of, 363 — Sulfichlhyolate, 739 — Superphosphate, Syrup of, 421 — Sweet, Wine of, 539 — Tonol, 776 — Troches of, 517 — Tropon, 776 — Valerianate, Elixir of, 88 — Vanadinate, 776 — Wine of, 538 Isarol, 776 Isinglass Plaster, 307 Isoform Powder, 776 Isonaphthol, 777 Isophypostigmine,. 777 Isopral, 777 Itch, Barber's, 547 — in Sheep, 638 — Remedies for, 578 Itching, in Cattle, 627 Itrol Crede, 777 Ivory, Bleaching, 1129 — Coloring, 1129 — To Color Black, 1101 Ixora Extract, 904 Izal, Medical, 777 Jaborandi, Elixir of, 89 — Fluidextract of, 155 — Tincture of, 485 Jacob's Powder, 316 Jackson's Pectoral Syrup, 427 Jalap Com., Tincture of, 485 — Extract of, 156 — Fluidextract of, 156 — Pills, 300 — Powder, Comp., 321 — Resin of, 327 — Soap, 339 — Tincture of, 485 Jamaica Dogwood, Tincture of, 485 Fluidextract of, 156 Extract, 570 James' Powder, 316 Janaer Tropfen, 91 Janeway's Pills, 300, 777 Japans, 1129 Jasmine Extract, 904 Jasmin, Oil of, Artificial, 889 Jaundice in Cattle, 628 Horses, 611 Javelle Water, 347, 1130 Jecorin, 777 Jecorol, 777 Jequiritin, 661 Jequiritol, 778 Jesson's Dental Anaesthetic, 778 Jesuit's Drops, 19, 52, 458 Jewelers' Roup-e, 1130 Jew's Beer, 541 Jewsbury & Brown's Oriental Tooth Paste, 778 Jockey Club Extract, 904 Sachet, 921 Joret & Homolle's Apiol Capsules, 778 Joy, Oil of, 257 Judkins' Ointment, 778 Juglans, Extract of, 136 Jim Crow Corn Salve, 778 Juices, 218, 219 Juniper and Potassium Acetate Elixir of, 89 — Berry, Syrup or Juice, 219 — Comp., Spirit of, 383 — Fluidextract of, 156 — Juice, 219 — Species, 380 lutes, 219 Jute, Carbolated, 220 — Iodoform, 220 — Mercuric Chloride, 220 — Salicylated, 220 Kadiol, 778 Kahama Urethral Bougies, 778 Kaiser Piller, 298, 778 Kalendol, 778 Kali-Caffeine, 778 Kali Lange, 370 Kalydor, 778 Kampfer Draaber, 50, 384 Kanel Draaber, 50 Kaolin Paste, 25, 287 Karmeliter Keist, 385 Kasagra, 778 Kastanol, 779 Kasucolum, 779 Katharol, 779 Kava Kava Fluidextract of, 156 Keating's Cough Lozenges, 779 Keimol, 779 Kelene, 779 Kentish's Liniment or Ointment, 231 1224 INDEX. Kelly's Collodion Paint, 34 Kenyon's Antiseptic Powder Comp., 779 Kephalgine, 779 Kephalopin, 779 Kepler Solution, 779 Kern's Insect Annihilator, 779 Kerosene, Disguising Odor, 1130 — Liniment, 580 Kestin, 779 Kew Garden Flowers Extract, 904 Kickapoo Indian Oil, 779 Kidney Remedies, 578 Kinder Balsam, 526 — Pulver, 320, 324 Kinewin, 779 King's Dandelion and Quinine Bilious and Liver Pills, 779 — Entozoic Powder, 324 — Expectorant Tincture, 488 — Royal Gometeur, 780 Kins Comp., Tincture of, 486 — Glycerite of, 199 — Powder, Comp., 321 — Tincture of, 485 Kinsel's Tasteless Cod-Liver Oil Com- pound, 779 Kiss.ingen, Effervescent Salt, Artificial, 333 — Salt, Artificial, 334 Kiss-Me-Quick, Extract, 904 Kjoelende Pulver, 319 Klaproth's Tincture of Iron, 483 Klyne's Nerve Restorer, 780 Kneipp's Pills, 302 — Remedies, 220 Knife Handles, to Fasten, 1130 Knight's Pills, 780 Koelrenter's Tincture of Rhubarb, 500 Koenig's Hamburg Breast Tea, 780 Koerner, 202 Kola Celery Tonic, 1028 — Digestive Tablets, 780 — Elixir of, 87 — Extract of, 156 — Fluidextract of, 156 — Koloid, 780 — Liquid Extract of, 156 Kalasaya, 1028 Kola Stearns, 780 — Syrup, 1028 — Wine of, 539 Kolaton, 780 Kondon's Catarrh Jelly, 780 Koepulin, 780 Koryl, 780 Kouesein, 780 Konsso, Infusion of, 207 — Fluidextract of, 156 Krameria, Extract of, 173 — Infusion of, 208 — Tincture of, 498- — Troches of, 518 Krampf Pulver, 320 Kresamine, 780 Kreso, 780 Kronessens, 91 Kryofin, 780 Kugloids, 781 Kumysgen, 781 Kurella's Powder, 321 Kurin, 781 Labarraque's Solution, 349 Label Ink, 1116 — Varnish, 1130, 1181 Labels on Tin, to Stick, 1144 Lac Ammoniac, 111 — Asafetida, 111 — Bismo, 781 — Bismuthi Cum Pepsino, 781 — - Magnesii Hvdrati, 791 Lac Sulfur, 391 Lacquers, 1130 Lactagol, 781 Lactate of Iron, Elixir of, 83 Lactated Pepsin, 781 — Pepsin, Elixir of, 94 Lactenzyme Elixir, 781 — Powder, 78 Lactocresol, 781 Lactol, 781 Lactonaphthol, 781 Lactone, 781 Lactopeptine, 781 Lactophenin, 781 Lactoserve, 781 Lacto-Somatose, 782 Lactucarium, Fluidextract of, 157 — Opiated, Syrup of, 422 — SyruD of, 422 — Tincture of, 486 Lactylphenetidin, 781 Ladies' Choice, 1029 — Slipper, Fluidextract of, 157 Powder, Comp., 321 — Spice Bitters, 22 Lady Hesketh's Dinner Pills, 291 Lady Webster's Dinner Pills, 291 Lafayette Cologne, 914 Laird's Bloom of Youth, 782 Lait Virginal, 950 La-Kama, 782 Lamaroux's Pectoral Syrup, 782 Lamellae, 49 Laminitis, Remedies for, 607 Laminoids, 782 Lamotte's Golden Drops, 483 Lancaster Black Drop, 522 Lanesin, 782 Langell's Asthma Remedy, 782 Lanichol, 782 Lanolin Cold Cream, 937 — Cream, 937 — Hair Lotion, 989 — Jellv, 953 — Milk, 949 INDEX. 1225 — Paste or Cream, 956 — Pomade, 956 Lanum, 782 Lapactic _ Pills, 782 Lapis Divinus, 39 Lard, 221 — Anhydrons or Dehydrated, 222 — Benzoinated, 222 Lards, Factitions, 223 Largin, 782 Laroche's Quina, 782 Laroze's Syrup of Orange Peel, 782 Lartigues's Gout Pills, 783 Laryngitis in Dogs and Cats, 650 — in Horses, 612 Lassar's Paste, 287 — Red Sulfur Ointment, 274 Laudanum, 491 Laundry Bluing, 1131 — Gloss, 1131, 1175 — Inks, 1112 Lavender Ammonia, 1019 — Comp., Fluidextract of, 157 Spirit of, 487 Tincture of, 487 — Drops, 487 — Extract, 904 — Lotion, 1019 — Sachet, 922 . — Smelling Salts, 928 — Spirit of, 385 — Water, 915 Laville's Anti-Gout Liquor, 783 — Preventive Pills, 783 Lavoline, 783 Lavoris, 783 Lawn Fertilizer, 1131 Laxagrada, 783 Laxan, 783 Laxatina, 783 Laxative Cordial, 783 — Cordial, 833 — Elixir, 67 — Pills, 300 Comp., 300 — Post Partum, Pills, Barker's, 300 — Species, 380 Laxatol, 783 Lead Acetate Ointment, 266 — and Opium, Injection of, 212 Lotion or Wash, 233 — Carbonate Ointment, 266 — i — Ointment Camphorated, 266 Plaster, 309 — Hair Dyes, 994 — Iodid Ointment, 266 Plaster, 309 — Ointment, 266 Comp., 266 — Oleate, 277 — Paste, Unnas, 287 — Plaster, 308 Comp., 309 — Subacetate Cerate, 28 — — Glycerite of, 199 — — Liniment of, 227 Ointment, 266 Solution of, 364 — Suppositories, Comp., 399 — Tannate Ointment, 266 Paste or Pultiform, 223 — Water, 364 Leather Blacking, 1131 — Cement, 1057 — Cleaning Paste, 1131 — Dressing, 1132 — Dyeing, 1132 — Polish, 1132 — Varnish, 1132 Lebel's Scordium Pills, 783 Leben's Essenz, 91 Lebeuf's Coal Tar, 783 Lecin, 783 Lecithin, 783 — Glycerole, 784 — Solution, 784 Lecithine Clin, 784 — Gare's, 784 Lecithmedullin, 784 Lecitogen, 784 Lecithol, 784 Leeches, Keeping of, 1132 Lehrer's Croup Powder, 784 Leinol, 784 Lemke's Electric Liniment, 784 Lemon Cold Cream, 93 — Cream, 938 — Juice, Artificial, 219 — Oil of, Artificial, 889 — Peel, Tincture of, 487 — Spirit of, 385 — Syrup of, 422 Lenicet, 784 Lenigallol, 784 Lenirobin, 785 Lenitive Electuary, 38 Leptandra Comp, Pills, 300 — Extract of, 147 — Powder, Comp., 321 — Tincture of, 473 — Fluidextract of, 147 Lentin, 785 Leontin, 785 Lepine, 785 Lepine's Granules Hydrocotyle Asiatica. 785 — Syrup Hydrocotyle Asiatica, 785 Leprine, 785 Leprotine, 7.85 Lera's Solution Pyrophos, Iron and Soda, 785 Letalbin, 785 Lencogon Tablets, 785 Levulose, 785 Levurargyre, 785 Lianthral, 785 1226 IXDEX. Libradol, 785 Library Paste, 1133 Lice, Application for, 579 — Exterminators for Dogs and Cats, 650 — on Cattle, 628 Poultry, 655 Licorice, Elixir of, 87 — Extract of, 158 — Fluidextract of, 159 — Glycerite of, 199 — Syrup of, 422 — Aromatic, Elixir of, 90 Syrup of, 423 — Comp., Elixir of, 90 Tincture of, 517 — Extract, Solution of, 364 • — Powder Comp., 321 — and Opium, Troches of, 517 Opium, Wine of, 539 Yerba Santa, Syrup of, 423 Ammonium Chlorid Comp., Elixir of, 87 Life, Elixir of, 91 — Essence of, Augsberg, 123 Ligature, Mercuric Chlorid, 27 Ligatures, 224 — Catgut, 25 — Formaldehyde, 27 — Oil Juniper, 27 — Silk, 336-337 Lightning Iodin Liniment, 580 Lignol, 785 Lilac Extract (Lilac Blossom-White Lilac), 904 — Water, 916 Lilacine, 888 Lilionese, 973 Lily, 926 — (Gold) Extract, 905 — Water, 973 — (White) Extract, 905 — of-the- Valley Extract, 905 Tincture of, 471 Flowers, Fluidextract of, 159 Root, Fluidextract of, 159 — Oil, 257 Lime Juice and Glycerin, 991 Pepsin, 219 Fizz, 1029 — Liniment of, 227 — Slip, 1029 — Syrup of, 423 — Water, 530 Linalool, 888 Linalyl Acetate, 888 Lincoln's Hop and Celery Nerve Tab- lets, 786 Linctus, 224 Linden, Tincture of, 487 — Water, 530 Liniments, 224-231, 580 — for Horses, 612 Linogen, 786 Linoleum, to Clean, 1133 Linonine, 786 Linseed, Infusion of, 207 — Mucilage of, 249 — To Keep Insects from, 1133 — Comp., Infusion of, 207 — Oil, Emulsion of Dr. Thompson's, 120 Mixture, 245 — Poultice, 314 Lip Glue, 1096 — Pomades, 966 — Salves, 966 Liviodol, 786 Lipobromol, 786 Liquefied Carbolic Acid, 11 — Sodium Phosphate, 376 Liquid Bismuth, 346 — Butter of Antimony, 344 — Cathartic, 786 — Cosmetics, 960 — Dentifrices, 1011 — Extracts, 159, 232 — Face Paints, 960 Febrisol, 786 — Glycerin Soap, 975 — Hsemoferrum, 786 — Hypophosphites Lime and Soda, 786 — Lactopeptine, 786 — Opodeldoc, 229, 389 — Oxyhemoglobin, 756 — Pepsin, 369 — Peptonoids, 786 — Peptonoids with Cascara, 786 — Peptonoids with Coca, 786 — Peptonoids with Creosote, 786 — Petrolatum, 257 Compound, Emulsion of, 120 — Soaps, 973 — Somatose, 787 — Taka-Diastase, 787 — Tar Soap, 975 Liquidsmber, Svrup of, 424 Liquids, 983 Liquiritiae, Succus or Extractum, 158 Liquocide, 787 Liquor Ambrosia, 787 — Antisepticus, 344 Volkmann's, 787 — Aromaticus, 787 — Diastos, 787 — Eucalyptus Comp., 862 — Ferri et Mangani Peptonatus, 722 — Ferro et Mangano Peptonatus, 739 — Ferri-Mangan, 787 — Ferri-Mangan Comp., 787 — Ferri-Mangani Bromopeptonati "Dieterich", 693 — Ferrisenic, 761 — Ferro-Mangan Aromaticus, 787 — Brompeptonati, 787 Iodopeptonati, 774 INDEX. 1227 Peptonati, Dieterich, 787 — Fluidextract of, 160 — Hypophosphitum, 786 London Paste, 287 — Lappae Comp., 787 Long Life, Elixir of, 91 — Poncreaticus, 787 Species, 380 — Sedans, 787 Loomis' Cholera Mixture, 242 — Sedans with Cascara, 787 Loretin, 789 — Strychnial, 377 Losophan, 789 — Thyroidei, 377 Lotis Alba, 234 — Tritici, 788 — Ammoniacalis Camphorata, 532 — Uterans, 787 — Cinchonse Comp., 789 Liquores, 340 — Flava, 234 Liquozone, 788 — Pancreatis, 789 Listerine, 788 Lotion for Sweaty Hands, 971 Lister's Antiseptic Solution, 344 Lotions, 232-234, 984 — Carbolic Paste, 286 Laxalotio, 789 Litharge Plaster, 308 Lozenges, 234, 514 Lithiated Hydrangea Comp., 788 Lubraseptic, 789 — Sorghum Comp., 788 Lubricant, Surgeons, 234 Lithium Arrhenal, 788 Lubricants, 1133 — Bromid, Elixir of, 91 Lubri-Chondrin, 789 — Carbonate, Effervescent Salt, 333 Lucilline, 789 — Citrate, Effervescent Salt, 332 Lugol's Solution, 353 Elixir of, 91 Lumbago Plaster, 309 — Ichthyol, 788 Luminous Paint, 1133 — Salicylate, Elixir of, 91 Lumpy Jaw, Remedies for, 628 — Tonol, 786 Luperine, 789 Lithona, 788 Lupulin, Elixir of, 91 Litholine, 788 — Extract of, 160 Lithograph Ink, 1115 — Fluidextract of, 160 Lithos, 788 — Aleoresin, 281 Lithyol, 788 — and Sodium Bromid, Elixir of, 91 Litmus, Test Solution of, 365 Lurline Extract, 905 — Paper, 284 Lutein, 789 Liver of Sulfur, 313 Lycetol, 789 — Medicines, 58] Lycopodium, Tincture of, 488 — Patches for, 971 Lygosine, 790 Liniodendron Extract, 905 — Quinine, 790 Lloyd's Hydrastis, 788 Lymphoids, 790 — Leontin, 788 Lymph-Orchitic Fluid Compound, 790 — Urethral Injection, 212 Lyptol, 790 Lobelia, Ethereal, Tincture of, 488 Lypan, 790 — Fluidextract of, 160 Lyjargine, 790 — Syrup of, 424 Lysidine, 790 — Tincture of, 487 Lysoform, 790 — Vinegar of, 522 Lysol, 790 — Comp., Fluidextract of, 160 Lysulfol, 790 — Comp., Lotion, 233 Lytrol, 791 — Comp., Pills, 300 — Comp., Tincture of, 488 Mabel Bouquet, 906 — Poultice, 314 Mac Alister's Cough Mixture, 791 — Powder, Comp., 322 Macassar Oil, 979 — and Capsicum, Tincture of, 488 MacKenzie's Gargle, 186 Locock's Hair Lotion, 989 Mage's Emulsion, 791 — Pulmonic Wafers, 789 Magen Tropfen, 52, 459 Locust Blossom Extract, 905 Magendie's Tincture of Iodin, 482 Loeffelkraut Spiritus, 389 Strychnine, 505 Loeffler's Solution, 484 Magnesia and Asafetida Mixture, 245 With Menthol, 484 Rhubard Powder, 322, 324 Lofotal, 788 — Magina, 238 Lofotin, 789 — Troches of, 517 Logan's Plaster, 309 Magnesiathol, 791 Logwood, Decoction of, 46 Magnesium Borocitrate, Solution of, 365 — Extract of, 160 — Borocitrate Tincture of, 488 1228 INDEX. — Bromid, Solution of, 365 — Carbonate, Solution of, 365 — Chlorid, Solution of, 366 — Citrate, Effervescent Salt, 333 — Citrate Solution of, 366 — Dioxid, 791 — Lights, 1133 — Perhydrol, 791 — Sulfate, Effervescent Salt, 333 Effervescent Solution of, 366 — Tartrate, 235 Magnesium Tonol, 791 Magnetic Balm, 798 Maidenhair, Syrup of, 424 Mairan Butter, 266 Maizavena, 791 Maizine, 791 Maizo-Lithium, 791 Malakin, 791 Malarin, 791 Malate of Iron, Crude, 129 Tincture of, 475 Male Fern, Oleoresin, 282 Malix, 791 Mallin, 792 Malt and Iron, Elixir of, 91 — Fluidextract of, 161 — With Alteratives, Extract of, 162 — Extract of, 160 With Beef, 162 With Beef, Wine and Iron, 162 With Cascara Sagrada, 162 With Cod Liver Oil, 162 and Hypophosphites, 162 and Hypophosphites of Calcium, 163 and Iodid of Iron, 163 and Iron, 163 and Iron and Quinine Citrate, 163 and Pancreatin, 163 Pancreatin and Pepsin, 164 and Pepsin, 164 With Cod Liver Oil and Phos- phorus, 164 With Gentian and Iron Chlorid, 164 with Heroin and Hypophosphites, 762 With Hypophosphites, 164 With Hypophosphites of Cal- cium, 164 and Hops, 164 and Iron, 165 W r ith Iron Iodid, 165 and Quinine Citrate, 165 Quinine and Strychnine Citrate, 165 With Lime, 164 With Pancreatized Cod Liver Oil, 163 With Pancreatin, 165 and Pepsin, 165 With Phosphate of Iron and Quinii-e, 165 of Iron, Quinine and Strychnine, 165 With Syrup Phosphate Comp., 166 With Wine of Coca, 166 of Pepsin, 166 With Yerba Santa, 166 Malta Balsam, 19 Malted Emulsion With Cod Liver Oil, 162 Maltine, 791 — Combinations, 791 Malto-Fer, 792 — Jerbine, 792 Maltobeef, 792 Maltole, 792 Maltopepsin, 792 Maltopepsine Elixir, 792 With Glycerophosphates, 792 Maltosikat, 792 Maltzyme, 792 — Compounds, 792 Manaca and Salicylates, Elixir of, 92 — Fluidextract of, 166 Mandel Saft, 400 Mandelklei, 956 Mandrake Compound, 793 — Extract of, 166 — Powder Comp., 322 — Tincture of, 489 Manganese Glucosate Solution of, 366 — Hair Dyes, 994 — Hypophosphite, Syrup of, 414 — Iodid Syrup of, 424 — Phosphate, Syrup of, 425 — (Saccharated) Oxid, Syrup of, 425 — Tonol, 493 Manganauro, 793 Mange in Cattle, 628 Swine, 645 — Remedies for Dogs and Cats, 651 for Sheep, 638 Mangifera, Fluidextract of, 166 Manhattan Cream, 1029 Manicure Cosmetics, 1021 — Preparation, 1016 Manifold Paper, 1133 Maukalan, 793 Manna, Syrup of, 425 Manola, 793 Manufacturers, 879 Marble Busts, to Clean, 1133 — Cement, 1058 Marechale Sachet, 922 Maretin, 793 Marie Stuart Extract, 905 Marienbad Pills, 793 Marigold Flowers, Tincture of, 462 — Fluidextract of, 136 INDEX. 1229 Marjoram Ointment, 266 Markasol, 793 Marking Inks, 1112 Marmorekin, 793 Marrol, 793 Marrow, 235 — Hair Pomades, 982 Marshall's Catarrh Snuff, 793 — or Hudson's Dentifrice, 1005 — Pills, 793 Marshmallow Ointment, 267 — Species, 380 Marsitriol, 793 Mary Thistle, Tincture of, 489 Massage Creams Fatty, 942 Rolling, 940 — Emollient, 942 Masses, 235-237 Mastic Comp., Spirit of, 385 Material Salve, — Mathematics, 1133 Matico, Elixir of, 92 — Fluidextract of, 166 — Comp., Elixir of, 92 Matricaria Comp., Tincture of, 466 Matterer's Cod Liver Oil Tablets, 777 May-Aople, Fluidextract of, 166 Tincture of, 489 — Bells Extract, 906 — Blossom Extract, 906 — Fern Extract, 906 Mayer's Ointment, 266 McArthur's Syrup Hypophosphites Comp., 793 McClure's La Grippe Tablets, 794 McDougall's Disinfecting Powder, 794 McMunn's Elixir of Opium, 794 Meadow Queen Extract, 906 Meatox, 794 Mecca Compound, 794 Medicamentum, 256, 794 Medicated Gelatins, 195 — Lint, 232 — Waters, 526 Medications, Homeopathic, 237 Medicinal Soap, 339 Medieora, 794 Medulla, 235 Medullary Glyceride, 794 Medulline, 794 Melachol, 794 Mel AEgyptiacum, 231 — Depuratum, 203 Melieform, 794 Melissa, Spirit of, 385 — Comp., Spirit of 385 Mellita, 203 I Mel Maroba, 794 — Rosae, 203 Menispermum, Fluidextract of, 185 Mentha Piperita, Tincture of, 495 Mentho Eucalyptol, 794 | Menthol Liniment, 228 — Lotion, 951 — Pencils, 289 — Plaster, 309 — Smelling Salts, 928 — Snuff, 337 — Tablet, 955 — Tooth Cream, 1010 Mentholated Chloral, 30 — Cold Cream, 938 — Lanolin Cream, 956 — Toilet Cream, 947 Menthoxol, 794 Menthyseptic, 794 Mentone, 794 Menyanthus, Fluidextract of, 135 Mercatone, 794 Mercauro, 794 Mercolint, 795 Mercuralin Eye Salves, 75 Mercuramalgam, 795 Mercuran, 794 Mercur-Iodo-Hemol, 795 Mercuriol, 795 Mercuriol Balsam, 268 — Embrocine, 795 — Hair Dyes, 994 — Lotion, 234 — Ointment, 267 Milder, 261 — Plaster, 310 — Suppositories, 399 Mercuric and Ammonium Chlorid, So- lution of, 367 — Chlorid Cotton, 43 Gauze, 192 Tincture of, 489 — Iodide, Red, Ointment, 268 Syrup of, 425 — Nitrate, Ointment of, 268 Ointment, 268 Ointment, Diluted, 268 Solution of, 367 — Oleate Ointment, 268 — Oxid Ointment, 269 Red, Ointment, 268 — Sodium Phenyldisulfonate, 761 Mercuricide Ointment, 795 Mercuro-Zinc Cyanid Gauze, 193 Mercurocreme, 795 Mercurods, 795 Mercurol, 795 Mercurovanillin, 795 Mercury Albuminate, Solution of, 367 — Ammonio-Chlorid Ointment, 267 — and Potassium Iodid, Solution of, 368 — Anilinate, 795 — Chlorid, Solution of, 367 — Cyanid, 796 — Glycolate, 796 — Ichthyolate, 770 — Liniment of, 227 — Mass of, 237 1230 INDEX. — Ointment, Comp., 267 — Oleate of, 278 — Oxycyanid, 796 — Paraphenylsulfonate, 767 — Peptonate, Solution of, 367 — Pill, 237 — Salicvl-Arsenate, 729 — Salicylate, 796 — Soluble, Hahnemann's, 238 — Stains, To Remove from Silver, 1134 — Succinimide, 796 — Tannate, 796 — Thymolacetate, 796 — With Chalk, 238 — With Magnesia, 238 Merrell's Vaginal Discs, 796 Mesotan, 796 Metaarsenic Anilid, 680 Metaiodoorthooxygenoline-Sulfonic Acid, 789 Metal Coloring, 1134 — Polishes, 1134 — Stamp Ink, 1117 Metallic Pills, 300 — Trees. 1134 Metaphenvlenediamine Hvdrochlorid, 796 Methacetin, 796 Methaform. 796 Methozin, 673 Methozin, 797 Methoxv-Acetphenetidin, 780 Methsohiles, 797 Methyl Acetylsalicylate, 797 — Anthranilate, 888 — Benzoate, 889 — Bichlorid, 797 — Gallate, 746 — Pyrocatechin, 753 — Rhodin, 797 Methvlacetanilid, 737 Methylal, 797 Methylatropine Nitrate, 735 Methvlditannin, 857 Methylene Bichlorid, 797 — Blue, 797 Compound, 797 — Bromtannin Urea, 693 — Creosote, 826 — Dicotoin, 745 — Disalicylic Acid, 744 — Hippuric Acid, 763 Methvloids, 797 Metral Disks, 797 Metrogrycerin, 797 Metrowine, 798 Metteaner's Laxative Aperient, 340 Metz's Balsam, 19 Mevian Ointment, 266 Mezereon, Extract of, 166 — Fluidextract of, 166 — Ointment. 269 Mialhe's Elixir of Pepsin, 798 — Tooth Powder, 1005 Mica in Stoves, to Clean, 1134 Mice Exterminators, 1134 Microcidin, 798 Mignonette, 925 Migraine Pencils, 289 Migrainin, 798 Migrophene, 798 Mikado Bouquet Extract, 906 Mildew, to Remove, 1134 Milk Fever, 629 in Cattle, 630 in Swine, 645 — for Diministed, 628 — of Almond, 110 — of Ammoniac, 111 Asanfetida. Ill Bismuth, 798 Cucumbers, 949 Megnesia, 238, 798 Roses, 950 Sulfur, 391 — Powder, Humanized, 322 — Red or Blue, Remedies for, 628 — Sugar Rennet, 817 Millefleurs Extract, 906 — Sachet, 922 Miller's Phosphorized Elixir Gentian, 798 — Universal Balm, 798 Mill's Pulmonic Syrup Comp., 798 Minerograph Ink, 1116 Mineral Glycerin, 750 Mint, Tincture of, 504 Miraculous Plaster, 310 Mirinol, 798 Mirrors, Frosting, 1135 — Making, 1166 Miscellaneous Cosmetic Preparations, 973 Mischolin, 798 Mistura Corrigens, 798 — Quinqui Iodidorum, 798 — Smilacis Compositus, 139 — Vulneraria Acida, 18 Mitchella Comp., Elixir of, 79 — Comp., Syrup of, 425 Mixed Treatment Pills, 300 Mixtures, 239-247 Mixture Creosote Comp., 799 — Glyconin Comp., 799 — Hvdrastis Comp., 799 — of Five Iodids, 798 — Phosphorus Comp., 799 Modeling Wax, Dental, 1135 Moder Draaber, 52 Molasses Poultice, 314 Mold in Cellars, to Prevent, 1135 Molds for Taking Impressions, 1135 Moles, to Remove, 582 Mollin, 247, 799 Mollisin, 799 Mollosin, 799 INDEX. 1231 Momberger's Powder, 319 — Elastic, 1139 Monobenzoyl-Arbutin, 702 — Pencil, 1139 Monobromated Camphor, Emulsion of, — Stick, 1139 120 Mucogene, 800 Monobromphenol, Ortho-, 799 Mucuma, Tincture of, 472 Monochlorphenol, Ortho-, 799 Mueller's Fluid, 1139 Monochlorethane, 732 Muguet, 888 Monoparaphenetidin-Citric Acid, 676 Mugwort Root, Tincture of, 489 Monotal, 799 Muiracithin, 800 Monsel's Solution, 363 Mullein, Fluidextract of, 166 Monte Carlo Extract, 906 Mulls, Plaster and Salve, 249 Morgan's Quincoca, 799 Mure's Syrup Bromid Potash, 800 — Cabalol, 799 Muriatic Acid, Diluted, 12 — Tissue Food, 799 Ointment, 265 — Vaginal Wafers, 799 Muscarine Nitrate, 800 Mormon Bishop Pills, 799 Musculine, 800 Morphine Acetate, Solution of, 368 Musculon, 800 — and Ipecac, Troches of, 517 Musk, Artificial, 887 — Citrate, Solution of, 368 — Extract, 906 — Comp., Syrup of, 426 — Root, Elixir of, 104 — Hypodermic Injection, 212 Extract of, 180 — Hydrochlorid, Solution of, 368 Tincture of, 505 — Meconate, Solution of, 368 — Sachet, 922 — Oleate, 279 — Tincture of, 489 — Powder, Comp., 322 Muskat Balsam, 20 — Stearate, 390 Mustache Dyes, 991 — Sulfate, Solution of, 369 — Preparation for, 973 — —Syrup of, 426 — Varnish, 998 — Suppositories, 399 Mustard Comp., Liniment of, 228 — Tartrate, Solution of, 369 — Liniment, 580 — Troches of, 517 — Liniment of, 228 — Valerianate, Elixir of, 92 ' — Paper, 284 Morrholine, Ferrated, 799 — Poultice, 314 Morrhumalt, 800 ~ — Spirit of, 385 Morrhuol, 799 — (White) Tincture of, 490 — Creosote, 799 Mutter Bakam, 526 Morrison's Pills, 799 — Salbe, 27, 261 Mortars, Mending, 1058 — Spiritus, 385 Morumalt, 800 — Tropfen, 52 — Preparations, 800 Mycodermine, 801 Mosquito Exterminators, 1135 Mydrol, 801 — Oil, 613, 630 Mydrine, 801 Moth Destroyers, 1136 Myelocene, 801 Moth Patches for, 971 Myronin, 801 — Removers, 968 Myrrh Comp. Lotion, 234 Mother's Cordial, 425 Tincture of, 490 Mother Drops, 52 — Pills, 300 Mother's Joy, 800 — Gargle, 590 Mother Plaster, 310 — Poultice, 315 Mother's Salve, 261 — Tincture of, 490 Mother Tinctures, 489 — Tooth Powder, 1005 Motherwort Compound, 800 Myrrholin, 801 Mott's Liniment, 228 Myrtol, 801 Mouches de Milan, 800 Mounting Paste, 1137 Naftalan, 801 Mourning Inks, 1108 Naiad Queen Extract, 907 Mousseline Extract, 906 Nail Bleach and Wash, 1021 Moussette's Neuralgia Pills, 800 — Cleaning Liquid, 1021 Mouth Glue, 1096 — Ointment, 1021 — Preparations, 1002 — Polish, 1021 — Washes, 1013 — Varnish or Enamel, 1022 for Infants, 1015 . Nalicin, 801 * Mucilages, 247-249, 1137 Napeline, 801 1232 INDEX. Na-Phoskol, 801 Neurosin, 804 Naphthalene, 801 Neurosine, 804 Naphthalin, 801 Neutralizing Cordial, 433 — Gauze, 193 — Elixir, 99 — Iodoform, 321 — Extract, Fluid, 174 Naphthalol, 683 New Mown Hay Sachet, 922 Napthocresol, 801 Extract, 907 Naphthoformin, 801 Naphthalin Paper, 1140 Naphthol, Alpha, 802 Nickel Plating, 1140 — Beta, 802 Nicolicin, 804 — Camphor, 802 Nichol's Elixir Peruvian Bark with — Paste, Lassnar's, 287 Protoxide of Iron, 804 Naphthoxol, 802 — Tasteless Cod-Livsr Oil, 804 Naphtosalol, 683 Nicotine Salicylate, 734 Narcenie Hydrochlorid, 802 Night-Blooming Cereus Extract, 907 — Sodium, 802 Nigridine, 804 — Sodium and Sodium Salicylate, 675 Niobe, Oil of, 889 Narcissus, Oil of, 889 Nipples, for Fissured, 583 Narcoform, 802 Nirvanin, 804 Narcotile, 802 Nitri Dulcis, Spiritus, 386 Narcotine, 802 Nitric Acid, Diluted, 14 Narcvl, 802 — — Ointment, 269 Nargol, 802 Nitrogenized Iron, 805 Narsol, 802, 854 Nitroglvcerin Comp., Elixir of, 92 Natroline, 802 — Pills, 297 Neapolitan Ointment, 261 — Spirit of, 385 Neat's Bronchiline, 802 — Tablets, 444 Nectriamin, 802 Nitro-Glycerin, Tincture of, 477 Neisser's Oil, 803 Nitrohydrochloric Acid, 15 Nenndorf Sulfur Soap, 803 Dilute, 15 Neodermin, 803 Nitromuriatic Acid, 15 Neoferrum, 803 Dilute, 15 Neoside, 803 Nitrous Ether, Spirit of, 386 Nepenthe, 803 Nizin, 805 Nephritic Pills, 803 Nizolysol, 805 — Powder, 323 Non-Freezing Solution, 1170 Nephritin, 803 Normal Salt Solution, 373 Ner- Vigor, 750 — Tinctures, 490 — Syrup, 803 Normalin, 805 — Tablets, 803 Norton's Chamomile Pills, 805 Nerf Dropfar, 384 Norwich Urethral Crayons, 805 Nerve and Bone Liniment, 580 Nosophen, 805 Nervitone, 803 Novargan, 805 Nervocidine, 803 Novaspirin, 805 Nervol, 803 Novocaine, 806 Nervous Debility, Remedies for, 582 — Base, 806 Nerve Drops, 52, 384 — Nitrate, 806 — Ointment, 269 Noury's Iodinated Wine, 805 — Powder, 321, 323 Xovozon, 806 Nettle Root, Fluidextract of, 167 Noxinol, 806 Neufaline, 803 Nucleo-Peptonate, 806 Neuralgia, Liniment, 580 — Ferri-Mangan, 806 — Mixtures, 583 Nuclein, 806 — Pills, 292 — Capsules, 806 Neuro-Lecithin, 804 — Solution, 806 Neuraline, 803 Nucleogen, 806 Neurilla, 803 Number Six, 464 Neurobion, 803 Nuremburg Plaster, 310 Neurocaine, 804 Nursery Powders, 963 Neurodin, 804 Nutgall and Opium Ointment, 270 Neuroguaiacol, 804 — Copying Inks, 1103 Neuronal, 804 — Ointment, 270 Neuronidia, 804 — Tincture of, 490 INDEX. 1233 Nutmeg Balsam, 20 Oleo Balsamic Mixture, 245 — Cerate, 29 Oleo Cocta, 256 — Spirit, 387 Oleo-Maltose, 808 — Tincture of, 491 Oleo-Stearate of Zinc, 728 Nu-Tone, 807 Oleocreosote, 808 Nutrient Fluids, 45 Oleates, 276, 280 — Gelatin, 1140 Oleoresins, 280-282 Nutritive, 807 _ Oleoresin of Capsicum Ointment, 270 — Hypophosphites, 807 Oleossacharates, 259 Nutrolactis, 807 Oleoze Comp., 808 Nutromulsion, 807 Oliophen, 808 Nutrose, 807 Olive Oil, Denatured, 1140 Nutryl, 807 Oliviers Biscuits Depuratif 808 Tincture of, 491 01 Paraffin. Pur., 686 Nux Vomica and Phosphorus, Elixir of, Omorol, 808 92 Onion, Syrup of, 426 Extract of, 167 Oophoin, 808 Fluidextract of, 167 Ophthalmic Ointment, 270 Water, 531 Opiated Powder of Ipecac, 321, 416 — Syrup, 426 Oakum, Medicated, 251 Ophthalmic Spirit, 387 Oat, Tincture of, 457 Opium, Acetated Tincture of, 492 Oats, Tincture of, 491 — ■ Ammoniated Tincture of, 492 Oidtmann's Purgative, 807 — and Camphor Pills, 301 Oil and Quinine Hair Tonic, 988 Lead Pills, 301 Oil, Cod Liver, Iodide, 254 — Benzoated, Tincture of, 492 With Iron, 253 — Camphorated, Tincture of, 492 — Emulsion, 110 — Comp., Solution of, 369 — of Catalpa, 889 Tincture of, 493 Narcissus, 889 — Confection of, 38 Ylang Ylang, 889 — Crocated, Tincture of, 493 — Triturates, 865 — Deodorized, 282 Oiled Paper, 1140 Tincture of, 493 Oil Cloth, To Furbish, 1140 — Extract of, 168 — Sugars, 259 < Scale, 169 — Sulfurated, 20 ■ for Smoking, 169 Oils, 251-259 — Fluidextract of, Camphorated, 170 — Bleaching, 1140 Deodorized, 171 — Concrete, 886 — Granulated, 282 — Essential, 883 — Liquid Extract of, 170 — Liniment of, 228 — Muriated, Tincture of, 494 — Comp. Liniment of, 228 — Pills, 301 Mixture of, 245 — Plaster, 311 — Camphorated, Mixture of, 245 — Powdered, 283 — Terpeneless, 886 — Powder, Comp., 323 — of Muguet, 888 — Sedative, Solution of, 369 — of Niobe, 889 — Tincture of, 491 Oily Bottles, to Clean, 1140 — Troches, 518 Ointments, 259, 276, 586 — Vinegar of, 522 Ointment, Brown, 27 — Wine of, 540 — for Birds, 657 Opnal, 808 Cosmetic Gloves, 958 Opodeldoc, Liquid, 229, 389 — — Dry Scalp and Hair, 991 Opoponax Sachet, 923 Ointments, Veterinary, 613 Opotherapeutics, 808 Obtundo, 807 Orange Blossom, 907 Ocean Spray Extract, 907 — Chocolate, _ 1029 Ochsenkreuz Pflaster, 307 — Comp., Elixir of, 92 Odda, 807 — Flower Skin Food, 943 Odontodol, 807 — Spirit of, 387 Odorless Coal Tar, 669 — Svrup of, 426 Oeillet, 888 — Tincture of, 494 Oel Seife, 338 — Ferrone, 1029 Olans, 808 — Ink, 1109 1234 INDEX. — Mint, 1029 Orangeine, 809 Orange Peel, Comp., Infusion of, 207 Infusion of, 207 — Comp., Spirit of, 388 Wine of, 92 Wine of, 540 — Elixir of, 92 — Flowers, Syrup of, 427 — Flower Water, 531 — Peel, Bitter, Fluidextract of, 171 Bitter, Tincture of, 494 (Sweet) Tincture of, 494 — Wine of, 540 Detannated, 540 Orchidin, 809 Orchidol, 888 Orchipin, 809 Orexoids, 809 Orgeat Rum, 917 — Syrup, 400 Oregon Grape, Fluidextract of, 131 Oresol, 809 Orexine Hydrochloric!, 809 — Tannate, 809 Oriental Cologne, 914 — Cream, 809 — Fizz, 1029 — Sachet, 923 Origanum, Oil of, 257 Orphol, 809 Orthoform-New, 809 Orthoform-New Hydrochlorid, 809 Orthoiodoanisol, 773 Osgood's Cholagogue, 810 Osier, Fluidextract of, 153 Osmic Acid, 810 Osmium Tetroxide, 810 Osmosum, 810 Ossalin, 810 Ouabain, 810 Ovadin, 810 Ovagal, 810 Ovaraden, 810 Ovariin, 810 Ovarine, 810 Ovaritone, 810 Ovaron, 810 Over the Waves, 1029 Ovo-Maltine, 810 Ovoferrin, 810 Oxalin, 811 Oxaphor, 810 Ox-Gall, Glycerite of, 199 Purified and Inspossated, 283 Tablets, Comp., 811 Oxid of Iron, Soluble or Saccharated, 215 Oxidizing Silver, 1140 Oxone, 811 Oxvchlorine, 811 — Dressing. 702 — Dusting Powder. 811 Oxycroceum Plaster, 307 Oxycymol, 700 Oxydasin, 811 Oxydendron, Compound, 811 Oxygen Aquae, 811 , — Compound, 811 — Talcum Powder, 965 Oxygenated Cold Cream, 038 — tooth Powder, 1005 Oxymel, Simple, 283 — Simple Squill, 283 Oxymethvlated Antifebrim, 796 Oxvnol, 811 Oxyntin, 81 1_ Oxyphenacetine Salicylate, 811 Oxyquinaseptol, 718 Oxysparteine Hydrochlorid, 811 Ozogen, 812 Ozolax, 812 Ozolyptol, 812 Ozomorn, 812 Ozomulsion, 812 Ozomin, 1140 Ozonized Water, 531, 812 Ozotone, 812 Pads, 812 Pagenstecher's Ointment, 270 Pager's Compound Syrup of Hvpophos- phites, 813 — Plain Hvpophosphites, 813 Pain Expefler, 813 — Relief, 581 Paine's Celery Compound, 813 Paint, Black, Glossy, 1140 — Bronze, 1140 — Emanuel, 1140 — Luminous, 1141 — to Mix, 1140 — Removers, 1142 Palmetol Pills, 813 Palmettine Hvpophosphites, 813 Palmetto Cordial, 813 — Suppositories, 813 — Tonic, 813 Palmiacol, 813 Palmo-Santal, 813 Palmothal, 813 Palpebrine. 813 Panama Hat?, to Clean, 1142 Pan-American Lemonade, 1029 Panase, 813 Pancreas, Elixir of, 93 Pancreatic Powder Comp., 323 — Solution, 369 Pancreatin and Bismuth, Elixir of, 93 — Bismuth and Pepsin, Elixir of, 93 — Elixir of, 93 — Pepsin Comp., 814 — Potassium and Rhubarb. Elixir of. 93 — Wine of, 540 Pancreatokinase, 814 INDEX. 1235 Pancreo-Bismuth, 814 Parrish's Camphor Mixture, 240 Pancreo-Digestin, 814 Parsley Comp., Infusion of, 207 Pancreopepsine, 814 — Root, Fluidextract of, 171 Pancrobilin, 814 — Tincture of, 494 — Pills, 814 Parson's Local Anesthetic, 816 Pancro-Pepsin, 814 Parturient Balm, 19 Elixir, 814 Paruchlorsalol, 815 Liquid, 814 Pas-Avena, 816 Panjecorine, 814 Paskola, 816 Pankreon, 814 Passiflora, Tincture of, 494 Panopepton, 814 Passion Flower, Tincture of, 494 Pan-Peptic Elixir, 814 Pasta Alumini Silicatis Comp., 751 Tablets, 814 Pasta-Mack, 816 Pantanberge's Solution, 817 Pastes, 286, 1137 Panzyme, 815 Paste for Cosmetic Gloves, 958 Papain, Elixir of, 93 — -—Photographs, 1144 Papavans, 815 — in Powder Form, 1144 Papers, 284 — Library, 1143 Paper, Carbon, 1142 Pasteurine, 816 — Carbonized, 1142 — Anti-Constipation Tablets, 816 — Ceresin, 1143 Pastilles, 514 — Hydrographic, 1143 — Glyco-Gelatin, 288 — Impermeable, 1143 Pastor Kneipp's Remedies, 220 — Oiled, 1143 Patchouhy Extract, 907 — Paraffined, 1143 — Sachet, 923 — Parchment, 1143 Patch's Exarysis Tablets, 817 — Razor, 1143 — Leucogon Tablets, 817 — Resin, 1143 Patterson's Pastilles, 817 — Tracing, 1143 — Powder, 817 — Waxed, 1143 Pava Pepin Comp., 817 Papilland's Antimony Granules, 815 Paves's Styptic Collodion, 35 Papier Fayard, 815 Peach Blossom Extract, 907 Paraacetanisidin, 796 Peacock's Bromides, 817 Paracetphenetidine, 821 Pearl d'Orient Extract, 907 Paradioxybenzene, 767 Pearson's Solution, 374 Paraf-Javal, 847 Peau D'Espagne, 924 Paraffins, 285 Extract, 907 Paraffin Cerate, 29 — —Sachet, 923 — Oil, 257 Pectoral Comp., Syrup of, 427 and Hypophosphites, Emulsion of, — Drops, 52, 495 120 — Elixir, 97 — Ointment, 270 — Powder, 321 Paraganglin, 815 — Species, 380 Parahemoglobulin, 760 — Syrup, 427 Paraldehyde, 815 — Tincture, 495 — Elixir of, 93, 816 Pectorin, 817 Para-Lysol, 816 Pediculin, 817 Paranephrin, 816 Pegnin, 817 Paraphenetidine Citrate, 707 Pelagin, 817 Paraplast, 816 Peleg White's Salve, 817 Pararegulin, 816 Pelletierine Tannate, 817 Paratoloid, 816, 866 Pellets, Homeopathic, 289 Paraxin, 816 Pellitorv, Tincture of, 495 Parchment Paper for Bottles, 1143 Pellotine Hydrochlorid, 817 Paregoric, 492 Pemzed, 817 — Concentrated, 170 Pencils, Cocaine, 289 — Elixir, 492 — Colored, 1145 Pareira, Fluidextract of, 171 — for Writing on Glass, 1145 — Tincture of, 494 — Iodoform, 289 Parisol, 816 — Paste, 287, 289 Parmese Violet, 910 — Salicylic Acid, 289 Parodyne, 673 Penne Suppositories. 818 Paroform, 815 Penne's Liquor Antiseptique, 818 1236 INDEX. Pennyroyal, Tincture of, 495 Perfumery, Colors for, 892 — Water, 531 Perfumes and Toilet Articles, 881 Penoform, 818 — Displaying of, 896 Pental, 818 — For Cold Cream, 938 Pepdilactine, 818 Hair Oil and Pomades, 980 Pepdilactic Elixir, 818 — Preservation of, 895 Pepper, Confection of, 38 — Synthetic, 887 — Ointment, 270 Perghityl, 819 — Oleorisin, 282 Perhydrol, 819 Peppermint, Spirit of, 388 Peritonitis in Horses, 613 — Syrup of, 427 Peronine, 820 — Tincture of, 495 Perosmic Acid, 810 — Troches of, 518 _ Peroxid Cold Cream, 938 — Water, 531 — Lotion, 951 Pepsin and Bismuth Effervescent Salt, — Tooth Cream, 1010 334 Peroxoles, 820 — Iron, Elixir of, 95 Perry's Moth and Freckle Lotion, 820 Ptelea, Elixir of, 95 Persian Balsam, 19, 458 Strychnine, Elixir of, 95 — Ink, 1116 Wafer Ash, 818 Persionis, Tincture of, 473 Elixir of, 95 Persodine, 820 — Aromatic, 289 Personne's Iodized Oil, 820 — Comp., Elixir of, 94 Peru Balsam, Syrup of, 427 Glycerite of, 200 Peruvian Bark, Tincture of, 467 Solution of, 370 Perugen, 820 — Cordial, 818 Peruol, 820 — Effervescent Salt, 334 Peruscabin, 820 — Elixir of, 94 Pestle Hundles, Cement for, 1058, 1145 — Essence of, 124 Peter's Peptic Essence Comp., 820 — Glycerite of, 199 Petro-Coco, 820 — Phosphate, 1029 Petrogen, 820 — Powder, Comp., 323 Petrol, 820 — Saccharated, 289 Petrol Oil, 820 — Solution of, 369 Petrolan, 820 Aromatic, 370 Petrolatum, 290 — Wine of, 540 — Camphor Ice, 955 Peoso-Ptelea, 818 — Oil, 257 Pepsol, 818 — ■ Saponated, Solid, 290 Peptenzyme, 818 Petrole-Alba, 821 — Elixir of, 818 Comp., 821 Peptic Digestant, 821 Petrolene, 821 Pepto-Brom-Eigon, 818 Petroleum Benzin, Purified, 21 Pepto Fer du Dr. Jaillet, 818 — Compound Emulsion, 821 Pepto-Iodo-Eigon, 819 Pills, 821 Pepto Mangan, Gude, 819 — Emulsion of, 121 Peptonate of Iron, Elixir of, 83 — Soap, 1145 Peptonic Pills, 819 — With Hvpophosphites, Emulsion of, Peptonized Glycerophosphates, 819 120 Peptonizing Powder, 323 Petroselinum, Tincture of, 494 Peptopancreatine Compound Elixir, 819 Petrosulfol, 771, 821 Powder, 819 Petrox, 821 Pepule Lecibrin, 819 Piperonal, 888 — Pancro Hepatic, 819 Phagacytin, 821 Perborate of Sodium, 819 Phalon's Vitalia, 821 Perchlorid of Iron, Solution of, 356 Phantom Bouquet, 1029 Tincture of, 483 Pharaoh's Serpents, 1145 Percoll, 819 Pharvngine, 821 Percutilan, 819 Phaselin, 821 Perdynamin, 819 Phenacetine, 821 Perfume Lozenges, 925 — Urethane, 860 Perfumed Waters, 912 — with Caffeine, Effervescent Salt, 334 — Ammonia Water, 1018 Phenaceto-Caffeine, 821 — Sea Salt, 1057 Phenalin, 821 INDEX. 1237 Phenanmine, 821 — Comp. Elixir of, 95 Phenamine, 822 Tincture of, 495 Phenatol, 821 — Elixir of, 95 Phenazone, 673 — Emulsion of, 121 Phenetidin, 821 — Iron, Quinine and Strychnine, Elixir Phenetidin Aceto-Salicylate, 822 of, 95 Phenocoll Hvdrochlorid, 82S - — Quinine and Strychnine, Elixir of, 96 Phenol-Bismuth, 822 — Mixture Comp., 824 — Camphor, 12, 24, 822 — Pastes, 1146 — Salicylate, 839 — Pills, 301 — Glycerite of, 197 — Solution of, 370 — Iodatum, 12 — Spirit of, 388 — Ointment, 262 — Tincture of, 495 — Sulforicinate, 822 Phosphotal, 824 — Suppositories, 397 Phosote, 823 — Troches of, 515 Phosphate, 823 Phenolid, 822 Photo-Library Paste, 1143 Phenolphthalein, 822 Phthisocan, 824 — Paper, 285 Phthisopyrin, 824 — Solution of, 370 Phylatacca, Tincture of, 495 Phenosal, 822 Physic, White Liquid, 290 Phenosalyl, 822 Physostigma, Extract of, 136 Phenthol, 822 Physostigmine, 731, 824 Phenyl Salicylate, 840 Physol, 824 — Urethane, 736 Phytoline, 824 Phenylacetamide, 661 Piano Covers, Rubber, to Clean, 1147 Phenylacetic Acid, 822 Piano Polish, 1147 Phenylbenzamid, 683 Picric Acid, 824 Phenylone, 673 Picratol, 824 Phenyldimethvlpyrazol, 673 Picrol, 824 Phenyo-Caffeine, 822 Pictures, to Transfer, 1147 Phesin, 823 Pierce's Golden Medical Discovery, 824 Phonozyme, 823 Pierian Spring Syrup, 1029 Phorxal, 823 Pierlot's Liquid Valerianate of Ammo- Phos. Tincture Cinchona Comp., 823 nia, 824 Phosphates Comp., Syrup of, 248 Pierre's Eau Dentifrice, 825 — of Iron, Elixir of, 84 Pil. Aphro., 825 Quinine and Strychnine, Gly- — Caulophyllen Comp., 748 cerite of, 200 — Hypo-Quinidol, 825 and Strychnine, Syrup of, — Orientalis, 825 429 — Palmetol, 825 Soluble, 215 Pile Remedies, 584 — with Quinine and Strychnine Comp., Pill Coating, 294 Syrup of, 430 # Pills, 290-304 Phosphatic Emulsion, 119 Pilocarpine Hair Tonic, 989 of Cod Liver Oil, 823 Pilocarpus, Elixir of, 89 — Mixture, 119 — Fluidextract of, 155 Phospherrin, 823 — Tincture of, 485 Phospho-Albumen, 823 Pilulae Imperiales, 778 — Caffein Comp., 823 Pimento Water, 531 — Glycerate of Lime, 823 Pimpinella, Tincture of, 496 — Lecithin, 823 Pine and Lanoline Ointment, 271 — • Muriate of Quinine Comp. 823 — and Somnos Cordial, 825 — Neurine, 824 Pineapple Ale, 1030 Phosphorated Cod Liver Oil, 254 — Bonbon, 1030 — Emulsion, 121 — Frappe, 1030 — Oil, 257 — Lemonade, 1030 Phosphoric Acid, Dilute, 15 — Paulette, 1030 — Elixir, 824 — Punch, 1030 — Water, 531 — Snow, 1030 Phosphorized Cerebro-Spinant, 745 Pineoline, 825 - Phosphorus and Strychnine, Elixir of, Pink-Ade, 1030 96 — Tea, Hot, 1030 1238 INDEX. Pinkeye Remedies, 611 — Ointment of, 271 Pinkroot and Senna, Fluidextract of, — Tincture of, 497 171 — Root, Fluidextract of, 172 — Powder, Comp., 324 Poultice, 315 Pinus Alba Compound, 825 Polish for Shoes, 1151 — Canadensis, Fluidextract of, 154 Stoves, 1150 — Comp., Fluidextract of, 183 Polishing Cloths, 1150 — Sylvestrio, Tincture of, 501 — Liquids, 1150 Piperazine, 825 — Paste, 1150 — Monomethvlarsinate, 825 — Powders, 1150 Piperoid, 281 — Starch, 1175 Piperazine Quinate, 845 Pollantin, 826 — Water, 825 # Polvform, 826 Piperidin-Guaiacolate, 825 Polyformin, 826 Pipsissewa, Fluidextract of, 172 Polymnia, Fluidextract of, 130 Piscidia, Fluidextract of, 156 — Ointment, 260 — Tincture of, 485 Pomated Tincture of Iron, 475 Piscin, 825 Pomegranate, Fluidextract of, 172 Pistachio Meal, 957 — Root Bark, Decoction of, 47 Pistoia Gout Powder, 825 Pomeranzen Elixir, 92 Pitch for Boats, 1147 Pommade Hongroise, 998 — Plaster, 311 Ponca Compound, 826 Cantharidal, 311 Pond's Extract, 826 Pittvlene, 826 Pope's Cure for Neuralgia, 827 Pixine, 826 — Sodium Salicylate Comp., 827 Plant Food, 1147 Papium, 827 — Insect Exterminator, 1147 Poppy, Syrup of, 430 Plantain, Tincture of, 496 — Tincture of, 497 Plantago, Tincture of, 496 Porcelain Cement, 1058 Plant's Asthma Cigarettes. 826 — Letters, to Fasten, 1058 Plasma, 201 Porous Alum, 18 — Nasal Tablets, 445 Potassio-Cuoric Tartrate, Solution of, Plasmon, 826 350 Plasters, 304-313 — Ferric Tartrate, 216 Plaster Mulls, 826 Potassium, Acetate and Bromid, Solu^ — of Paris Bandages, 20 tion of, 371 Formulas, 1147 and Juniper, Elixir of, 96 Plasticum. 826 Elixir of, 96 Plating with Gold, Silver, etc., 1148 Solution of, 371 Plais' Fit Powders, 826 — Arsenite, Elixir of Pleurisy Root, Fluidextract of, 172 — — Fowler's Solution, 372 Powder Comp., 324 — Boro-Tartrate, 445 Tincture of. 496 — Bromid, Effervescent Salt, 335 Pneumin, 826 Glycerite of, 200 Pneumonia in Cats, 652 Solution of, 372 Podophvllin. 328 with Caffeine, Effervescent Salt, — Comp., Pills, 301 335 — Powder Comp., 324 — Carbonate, Solution of, 372 — Tincture of, 496 — Chlorate, Glycerite of, 200 — Trituration of, 513 — — Suppositories, Comp., 399 — Troches of, 518 Tooth Powders, 1006 Podophyllum, Belladona and Capsicum Troches of, 518 Pills, 302 — Citrate Effervescent Salt, 335 — Fluidextract of, 166 Solution of, 372 — Resin of, 328 — Cyanide Ointment, 271 — Tincture of, 489 — Dichromate, Solution of, 373 Poehl's Physiologic Salt, 826 — Iodid Comp., Elixir of, 81 Poison Ivy, Tincture of, 496 — —Ointment, 271 — Nut, Tincture of, 492 Elixir of, 81 Poisoning of Horses, 613 Suppositories, 399 Poke, Comp. Pills, 302 — Nitrate Paper, 285 — Compound, Syrup of, 430 — Oxyquinolin Sulfate, 704 Tincture of, 497 — Permanganate, Solution of, 373 INDEX. 1239 — Sulfuret Ointment, 271 — Sozoidol 827 — Tonol, 828 Potato Poultice, 315 Potio Riveri, 313, 375 Pot Pourris, 926 Potsdam Balsam, 827 Poudre de Vicomtesse, 965 Poultices, 313-315 ^ Poultice, Thompsonian, 313 Poultry Medicines, 654 — Powders, 654 Poustaltic Pills, 819 Powder for Artificial Teeth, 1007 Powdered Extracts, 172 — Opium, 283 . Powders, 315, 325, 982 Powders, 982 Powell's Aniseed Balsam, 827 P. P. P., 812 Prsevalidin, 827 Precipitated Sulfur, 391 Prepared Suet, 391 Prescription 49, 688, 827 Preservation of Perfumes. 895 Price's Canning- Compound, 827 Prickley Ash Bark, Fluidextract of, 172 Berries, Tincture of, 497 — Elder, Tincture of, 497 Prima Purificans, 827 Primrose Extract, 908 Prince's Drops, 52 ' — Pine, Fluidextract of, 172 Prinsen's Ackta Draaber, 52 Probilin Pills, 827 Proferrin, 827 — Comp. Tablets, 827 Proof Brandy, 23 Proponal, 827 Proprietary and Synthetic Preparations, 659 Proprietatis, Elixir, 96 Propylamine, 827 Prostaden, 827 Protalbin Silver, 828 Protan, 828 — Compound Tablets, 828 Protargal, 828 tProtogen, 828 Protonuclein, 828 Protosal, 828 Protozone, 829 Protylin, 829 Prune Pulp, 325 Prunicine Tannate, 829 Prunicodeine, 829 Pruni-Heroin, 829 — Pepto, 829 Prunier's Hyperphosphine, 829 Prussic Acid, 12 Pseudohyoscyamine, 829 Ptelea, Elixir of, 106 -Wine of, 541 Puff Ball, Tincture of, 497 Pulmonary Balsam, 411 Pulmonic Elixir, 97 Pulsa Flora, 829 Pulsatilla, Tincture of, 497 Pulvis Digestivus, 323 — Diphtheriticus, 720 Pulvola, 829 Pumpkin Seed, Emulsion of, 121 Fluidextract of, 173 Oil of, 257 Puncture Cement, 1058 Purgatin, 829 Purgative Granules, 829 Purgatol, 829 Purgerine, 830 Purified Aloes, 17 — Antimony Sulfied, 18 — Benzin, 21 -Cotton, 39 — Talc, 445 Purifiers, Blood, 549 Puroform, 830 Purple Ink, 1109 Putty, Glaziers', 1151 Putz Pomades, 1151 — Tablets, 1151 Putzel's Elixir, 82 Pyohemol, 830 Pvoktanin, 830 Pyoluene, 830 Pyramidon, 830 — Salicylate, 830 Pyran, 831 Pyrantin, 831 Pyrenol, 831 Pyrethrum, Tincture of, 495 Pyridine, 830 — Tannate^ 831' Pyrocatechinmonoethylether, 753 Pyrodin, 831 Pyrodine, 766 Pyrodol, 831 Pyroferrine, 831 Pyrofistine, 831 Pyrogallic Acid Ointment Comp., 271 Pyrogallol-Bismuth, 831 — Hair Dye, 995 — Monoacetate, 734 — Triacetate, 784 Pyroglycerin, 831 Pyrophosphate of Iron, Soluble, 216 Pyrosal, 831 Pyrotechnic Papers, 1152 Pyroxylin, 325 Pyrozone, 831 Quadruplex Pills, 302 Quaker Black Drops, 522 Quartonol Tablets, 831 Quassia, Extract of, 173 — . Fluidextract of. 173 — Infusion of, 208 1240 INDEX. — Tincture of, 498 — Water, 531 Quatuor Pills, 302 Quebracho, Extract of, 173 — Fluidextract of, 173 Queen's Root, Fluidextract of, 179 Tincture of, 504 Quesneville's Cream of Bismuth, 832 Quickine, 832 * Quillajar, Fluidextract of, 178 — Tincture of, 503 — Tooth Washes, 1012 Quina Laroche, 832 Quinalven, 832 Quinaphthol, 832 Quince Seed. Mucilage of, 249 Quincoca, 832 Quinic Acid, 832 Quinidine. 832 — Svrup of. 431 Quinilid Tablets, 832 Quinine, Ammoniated, Tincture of, 498 — and Phosphates, Comp., Elixir of, 97 — and Cinchona Hair Tonics, 988 Strychnine. Elixir of, 98 Valerianates, Elixir of, 98 — Betanaphthol Sulfonate, 832 — Bisulfate, Elixir of, 97 — Comp. Pills, 302 Tincture of, 498 — Dibromsalicvlate, 691 — Elixir of, 69, 90 — Ethyl-Carbonate, 736 — Flower, Fluidextract of, 173 — Formate, 832 — Hydrochlorsulfate, 832 — Lygosinate, 832 — O'leate. 279 — Phospho-Muriate, Comp., Syrup of, — Powder, Comp., 324 — Salicylic Ether, 840 — Sulfate Pills, 302 With Strychnine, Glycerite of, 200 — Tincture of, 498 — Tonol, 832 — Tooth Powder, 1006 — Valerianate, Elixir cf, 98 and Strychnine, Elixir of, 98 — Wine, 541 Quinoline, 833 — Bismuth Sulfocyanid, 714 — Monohvpochlorid, 704 Quinolio, "833 Quinonin, 833 Quinopyrin, 833 Quinquinia, 833 Quittor, Remedies for 613 Rachitol. 833 Radal, 833 Radam's Microbe Killer, 833 RadclifTe's Elixir, 833 Rademacher's Cholera Mixtures, 242 — Preparations, 326 Radium Fluid, 833 Rainworm Oil, Artificial, 258 — Spirit, 388 Ransom's Hive Svrup and Tolu, 833 Raspberry Royal, 1031 — Svruo of, 431 Raspho,' 1031 Rat Catcher's Oil, 1152 — Exterminators, 1152 — Scents, 1152 — Virus, 681 Ratiers' Arsenical Caustic, 27 Razor Paper, 1153 — Pastes, 1152 — Strop Pastes, 1152 Raymond's Disinfectant, 833 Redbird's, Food for, 656 Red Clover Compound, 833 ■ Tincture of. 498 Comp., Syrup of, 432 — Drops, Hunter's, 52 — Gum, Fluidextract of, 173 Troches, 516 — Inks, 1109 — Lotion, 234 — Poppy, Syrup of, 432 — Powder, 325 — Precipitate Ointment, 268 — Root Comp., Svrup of, 432 — Wash, 234 Reduced Hemoglobin, 760 Reducing Solution for Photography, 1153 Reference List, 879 Refrigerant Ointment, 272 Regenwurm Geist, 388 — Oel, 258 Regnault's Pate Pectorale, 833 Regulin, 834 Remedies for Acne, 969 Pimples, 969 Renaden, 834 Renaglandin, 834 Renastvptin, 834 Renatone, 834 Renoform, 834 Renol, 834 Resaldol, 834 Resin Ointment, 29, 271 — Paper, 1153 — Plaster, 312 Comp.. 312 Resinol, 834 Resins, 327-328 — Bleaching. 1153 Resmoids, 328 Resolventes Species, 379 Resorbin, 834 Resorcin Cotton. 44 — Gargle, 591 — Gauze, 194 — Mcnacetate, 736 INDEX. 1241 — Ointment, Comp., 271 — Paste, Mild, 287 Resorcinol, 834 Respirazone, 834 Restorative Syrup or Cordial, 432 — Wine Bitters, 53.7 — and Relaxing Bitters, 21 Retinol, 834 Retort Cement, 1059 Reuter Salbe, 261 Rhatanv, Extract of, 173 Rhatany, Glycerite of, 200 — Infusion of, 208 — Syrup of, 432 — Tincture of, 498 — Troches of, 518 Rhatanv and Cocaine, Troches of, 518 Rhei-Drastis, 834 Rheumacilate, 834 Rheumagen, 835 Rheumatic Drops, 464 — Elixir of, 64 — Liniment, 229 Rheumatin, 835 Rheumatism in Cattle, 630 Dogs and Cats, 652 — Remedies, 585 for Sheep, 638 Rheumon, 835 Rhinol, 835 Rhodalline, 861 Rhodinol, 888 Rhomnal, 835 Rhubarb, Aqueous, Tincture of, 499 — Aromatic, Fluidextract of, 174 Syrup of, 433 Tincture of, 99 Tincture of, 499 — Comp., Fluidextract of, 174 Pills, 302 Tincture of, 499 — Drops, 52 — Elixir of, 98 — Extract of, 174 — Fluidextract of, 174 — Infusion of, 208 — Magnesia and Senna, Elixir of, 99 — Pills, 302 — Powder, Comp., 324 — Spiced, Syrup of, 433 — Sweet, Tincture of, 500 — Svrup of, 432 t— Tincture of, 498 — Vinous, Tincture of, 500 — Wine of, 541 — Wuerzburger Pills, 302 — and Gentian, Tincture of, 500 _ — and Magnesium Acetate, Elixir of, 99 — and Magnesia Powder, Anisated, 324 — and Potassa, Troches of, 519 — and Potassium Comp., Elixir of, 99 Fluidextract of, 174 Syrup of, 433 With Pancreatin, Elixir of, 99 Senna, Elixir of, 99 Fluidextract of, 174 Tincture of, 500 Rhus Aromatica, Fluidextract of, 174 Tincture of, 506 — Glabra, Fluidextract of, 174 — Toxicodendron, Tincture of, 496 Ricin, 835 Ricinol Grape, 835 Rickets in Colts, 614 Dogs and Cats, 652 Swine, 646 Calves, 631 Ricord's Capsules of Copaiba and Tar, 835 Ricqle's Alcool de Menthe, 835 Riga Balsam, Factitious, 20 Ringbone Cures, 614 Ringoline, 835 Ringworm Applications, 585 — in Cattle, 631 Horses, 614 Ripans Tabules, 835 Roach Exterminators, 1153 Robach's Bitters, 835 Robbert's Camphor Tar Ointment, 835 Roberts-Hawley Lymph Comp., 790 Robin's Pill Cascara Comp., 835 — Powder of Glycerophosphates, 835 Robinson's Elixir Paraldehyde, 835 — ■ Hypophosphites, 835 — Phosphoric Elixir, 836 Roboline, 836 Roborat, 836 Rache's Embrocation, 836 Rodagen, 836 Roge's Purgative Powder, 836 Rondelatia, Extract, 908 — Sachet, 923 Ronozol, Salts, 836 Root Beer Cream, 1031 Root Beer, Hot, 1031 Rose, 926 — Cold Cream, 938 — Comp., Infusion of, 208 _ — Confection of, 38 — d'Amour Extract, 908 — Fluidextract of, 175 — Geranium Extract, 908 — Honey of, 203 With Borax, 204 — Inspissated, Extract of, 175 — (Moss) Extract, 908 — (Musk) Extract, 908 — Sachet, 923 — Syrup of, 434 — (Tea) Extract. 908 — Tooth Powder, 1006 — (Turkish) Extract, 908 — Waters, 531 Ointment, 272 1242 INDEX. — (White) Extract, 908 — Hepatica, 837 — (Yellow) Extract, 908 — Lister, 837 Rosemary Ointment, Comp., 272 — Lithia Tablets, 837 Rosen's Broest Droppar, 539 — Marinum, 1156 Roseol, 888 — ■ Phvsiologicum, 837 Roseter's Hair Regenerator, 836 — Prunelle, 837 Rosinol, 834 — Volatile, Spirit of, 381 Rosin Cerate, 29 Salacetol, 839 Rosin Cerate, Compound, 29 Salactol, 838 Rotterine, 836 Salalgin, 838 Roup Remedy, 655 Salamid, 838 Rouges, 961 Salaperient, 838 Rubber Cement, 1059 Salazolon^ 839 — Goods, to Preserve, 1154 Salbromalid, 673 — Piano Covers, to Clean, 1154 Salenal, 838 — Stamp Ink, 1117 Salene, 838 Rubidium Bromid, 836 Salep, Mucilage of, 249 — Iodid, 836 Salibromin, 838 Rubini's Camphor, 463 Saliciform, 838 — Cholera Mixture, 242 Salicyl-Paraphenetidin, 791 Rubus, Syrup of, 402 Salicvlaldehydemethylphenylhvdrazine, Rue Oil, 258 664 • — Anemone, Fluidextract of, 175 Salicylated Collodion, Compound, 35 Rufus's Pills, 836 — Cotton, 44 Rumex Comp., Syrup of, 434, 441 — Gauze, 194 Runyons Label Paste, 1138 _ — Jute, 220 Ruschenberger's Cholera Mixtures, 242 — Cold Cream, 938 Russell Emulsion, 837 — Suet, 391 Russian Cholera Mixture, 242 — Tooth Paste, 1010 Rust Stain Removers. 1154 — Tooth Powder, 1006 Salicylate of Iron, Elixir of, 88 Sabalol, 837 Salicvlbromanilid, 838 — Balsam, 837 Salicylamide, 838 — Spray, 837 Salicylic Acid, Elixir of, 100 — Tablets, 837 Emulsion of, 121 Sabbatia Elliotti, Fluidextract of, 173 Glycerite of, 200 Saccharated Extracts, 177 Glvcerogelatin of, 202 — Ferrous Iodide, 215 Pencils, 289 — Oxid of Iron, Syrup of, 420 Salicvlos. 838 — Pepsin, 289 Salicvlous Alcohol, 839 — Solution of Lime, 423 Salifebrin. 838 Saccharin, 837 Saliformin, 838 — Elixir of, 99 Saligenin, 839 — Solution of, 373 Salinaphtol, 683 — Syrup of, 434 Saline Wash, 233 Sachet Powders, 919 Saliodin, 839 Sacrum, Elixir, 91 Salipvrine, 839 Safety Paint, 1155 Salit, 839 Saffron, Tincture of, 500 Salitannol, 839 Saffronized Tincture of Opium, 493 Salithvmol, 839 Sage, Infusion of, 208 Salitonia, 839 — Comp., Infusion of, 208 Salocoll, 839 — Hair Tonic, 989 Salocreol, 839 — Oil, 258 Salol, 840 Sajodin, 837 — Elixir of, 100 Sal Alembroth, 328 — Mouth Wash, 1014 Cotton, 41 — Tooth Powder, 1006 Gauze, 188 Salomon's Balm of Gilead, 840 — Aperiens, 837 Salophen, 840 — Carolinum Factitium, 328 Saloquinine, 840 — Codeia, 837 — Salicvlate, 840 — Eliminant, 837 Salosantal, 840 — Ethyl, 837 Salt of Lemon, Artificial, 1155 INDEX. 1243 — Rheum Remedies, 573 — Solution, Normal, 373 — Vichv, Artificial, 335 Salts, Effervescent, 329 Salubrin, 840 Salumin, 840 Salutis, Elixir of, 501 Salves, 586 Salve Mulls, 336 Salvitae, 840 Samaritan Punch, 1031 Sanatogen, 841 Sancodol, 841 Sandal-Etto, 841 Sand Mandelklei, 956 Sanded Almond Meal, 956 Sanford's Extract of Jamaica Ginger, 841 Sangostol, 841 Sangrenal Preparations, 841 Sanguestine, 841 Sanguestine Chlorid Solution, 841 Sanguinaria, Syrup of, 402 — Tincture of, 460 Sanguinal, 841 Sanguinol, 841 Sanguis Bovinus Inspissatus, 22 Sanitaris Metal Disks, 841 Sanitas, 841 Sanmetto, 841 San-Methyl, 841 Sanoform, 841 Sanolin-Bahr, 842 Sanose, 842 Sanosin, 842 Santal-Grape, 842 — Midy, 842 — Ostind, 842 Santalets, 842 Santalol Formaldehyde, 842 Santaloids, 842 Santheose, 842 Santolin Capsules, 842 Santonica, Tincture of, 510 Santonin and Podophyllin, Trituration of, 514 — Comp., Troches of, 519 — Troches of, 519 Santyl, 842 San Urina Cordial, 842 Saparaform, 842 Sapo Animalis, 338 — Unguinosis, 799 Sapocarbol, 842 Sapodermin, 843 Sapolan, 843 Saponaceous Tooth Washes, 1011 — Tooth Powder, 1007 Saponis Viridis, Tincture of, 477 Sapophthalum, 843 Sapozol, 843 Saprol, 843 Saratoga Ointment, 843 Sarsaparilla Comp., Decoction of, 47 Fluidextract of, 176 Stronger Decoction of, 48 Syrup of, 434 Weaker, Decoction of, 48 — Decoction of, 47 — Extract of, 175 — Fluidextract of, 175 — Syrup of, 434 Sassafras and Opium Mixture, 246 — Lotion, 234 — Pith, Mucilage of, 249 Saturated Tinctures, 500 Saturatio, 375 Satyria, 843 Savaresses' Capsules, 843 Savin, Tincture of, 501 Savine Cerate, 29 — Fluidextract of, 176 Savonal, 843 Saw Palmetto Comp., Elixir, 100 Saxin, 843 Scab, Sheep, Treatment for, 639 Scabies Remedies, 612 Scabiol, 843 Scale Pans, to Clean, 1155 Scalp Preparations for, 973 Scammonin, 843 Scammon's Cholera Mixture, 242 Scammony Comp. Pills, 302 Pills of, 303 — Powder Comp., 324 — Resin of, 328 Scarlet Ink, 1108, 1110 Scented Paraffin Cakes, 955 Scents for Attracting Animals, 1155 Schafhirt's Tapeworm Remedy, 594 Scheele's Hydrocyanic Acid, 13 Schistiol, 843 Schleich's Solution, 343 Schlotterbeck's Compound Mixture of Glyconin, 843 Hydrastis, 843 — Syrup Mangan Comp., 843 Phospho-Cloride Iron, 843 Schmier Seife, 338 Schneeberger Snuff, 337 Schreyer's Toothache Pellets, 843 Schroer's Hair Dye, 843 Schiiltze's Blood-Purifying Powder, 844 Scofulous Syrup, 441 Scoparius, Fluidextract of, 134 — Infusion of, 204 Scopola, Extract of, 176 — Fluidextract of, 176 Scopolamine Hydrobromid, 844 Scopomorphine, 844 Scotch Pine, Tincture of, 501 Scot's Pills, 292 Scott's Emulsion, 844 • Scratches, Remedies for, 614 Screw Worm, Remedies for, 614 Scudder's Alterative, 407, 472 1244 INDEX. Scullcap, Fluidextract of, 176 Scurvy Grass, Spirit of, 389 — in Sheep, 641 Sea Bath Salt, 1018 — Breeze, 907 — Foam Liquid, 976 — Salt, Artificial, 1156 — Water, Artificial, 1156 Sealing Waxes, 1156 Sear Cloth Plaster, 306 Secacornin, 844 Secretive Oil, 255 Sedalole Syrup, 844 Sedative, 673 — Compound Tablets, 844 — Granules, 844 — Water, 532 Seidlitz Powder Comp., 325 Seifen Geist, 389 Seigel's Curative Syrup, 844 Seiler's Antiseptic Solution, 345 — Solution, 373 — Tablets, 844 Senecin and Viburnin Tablets, 844 Senckenberg's Migraine Pastilles, 844 Senega, Fluidextract of, 176 — Infusion of, 208 — Syrup of, 435 — Tincture of, 501 Senna and Jalap, Fluidextract of, 178 — Rhubarb, Fluidextract of, 178 — Aromatic, Fluidextract of, 177 Syrup of, 435 — Compound, Confection of, 39 Elixir of, 101 Fluidextract of, 178 Infusion of, 209 Syrup of, 435 Tincture of, 501 — Confection of, 38 — Elixir of, 100 — Fluidextract of, 177 — Infusion of, 208 — Pods, Fluidextract of, 177 Liquid Extract of, 177 — Syrup of, 435 — With Manna, Syrup of, 435 Sennine, 844 Sepdelin, 844 Sepia, Trituration of, 514 Serosine, 844 Serpentaria Comp., Tincture of, 502 — Fluidextract of, 178 — Infusion of, 209 — Tincture of, 501 Serum Paste, 844 Sesquichlorid of Iron, Tincture of, 483 Seven Barks, 844 Fluidextract of, 155 Sevetol, 845 Sewing Machine Oil, 1157 Sextonol Tablets, 845 Shading Pen Ink, 1116 Shaker Digestive Cordial, 845 — Extract of Roots, 845 Shampoo Cream, 977 — Jelly, 977 — Liquids, 975 — Paste, 977 — Powders, 977 Shaving Creams, 999 — Pastes, 999 — Powders, 999 — Preparations, 999 Shazada Extract, 908 Sheep Dips, 639 — Laurel, Tincture of, 502 — Medicines, 636 Shellac, Bleaching, 1158 — Solution, 1157 Shepherd's Purse, Tincture of. 502 Shiloh's Consumption Cure, 845 Shoe Blacking, Liquid, 1158 — Blacking, Paste, 1158 — Dressing, Tan, 1159 White, 1160 — Finishers' Ink, 1116 — Grease, 1160 — Polishes, Patent Leather, 1161 Shoes, Tan. Blacking of, 1161 Shoe Varnish, Patent Leather, 1161 Shoes, Waterproofing, 1161 - Shoemaker's Remedy, 985 — Wax, 1161 Shoulder, for Lame, 614 — Lameness in Cattle, 631 Show Card Ink, 1116 — Globe Colors, 1162 Sic, 845 Siccatives, 1072 Sicco, 845 Siccols, 834 Sick-Room Perfume, 918 Sidonal, 834 — New, 846 Silberol, 846 Silica, 336 Silicate Cement, 1059 Silk Ligature, Carbolated, 337 Iodoform, 337 Mercuric Chlorid, 337 Silk Protection, Carbolated, 337 Silver-Casein, 677 — Citrate, 674 — Drops or Balsam, 256 — Fluorid, 856 — Hair Dyes, 992 — Ichthyol, 770 — Ink, 1110 — Lactate, 663 — Nitrate, Glycerite of. 201 Solution of, 373 Stains, to Remove, llfl^ Suppositories, 399 — Nucleide. 802 — Oxidizing of, 1165 INDEX. 1245 — Picrate, 824 Soda and Spearmint, Mixture of, 246 — Plating, 1165 — Comp. Lotion, 234 — Polish, 1165 — Mint, 246 — Protalbin, 782 — Mixture of, 246 — to Prevent Tarnishing, 1166 — Powder, 325 — Vietllin, 677 — Solution of, 373 Silvering of Glass, 1166 — With Lime, 340 Silverware, to Clean, 1167 Soda Water Preparations, 1023 Simple Cerate, 29 Sodio-Phos. Comp., 846 — Elixir, 101 Sodium Acetylsulfanilate, 712 — Emulsion, 110 — Acid Oleate, 736 — Syrup, 436 — Anhydromethylene Citrate, 707 Sim's Elixir of Calisaya, 70 — Arsenate, Exsiccated, 340 Sinews, for Strained, 614 Pearson's Solution of, 374 Singleton's Eye Remedy, 846 Solution of, 374 — Ointment, 846 — Betanaphtholate, 846 Sirolin, 846 — Bicarbonate, Troches of, 519 Sirsol, 846 — Boro Benzoate, 340 Six Bromides, Elixir of, 64 — Borate, Solution of, 374 — Iodids, Elixir of, 81 — Borosalicylate, 846 Skin Creams Non Greasy, 943 — Cocodylate, 679, 846 — Food, 942 — Carbonate Exsiccated, 340 — Preparations, 930 — Carbolate, Solution of, 379 — Whiteners, 962 — Chlorid, Solution of, 375 Skunk Cabbage, Tincture of, 502 — Cinianate, 762, 846 —Oil, 258 — Citrate, Solution of, 375 Slagvatten, 382 — Hypophosphites, Syrup of, 415 Slippery Elm, Mucilage of, 248 — Phosphate Comp., Solution of, 376 Poultice, 314 Effervescent Salt, 335 Smart Weed, Tincture of, 502 Exsiccated, 340 Smelling Salts, 927 — Citro Tartrate Effervescent Salt, 335 Smith's Solution of Bromin, 347 Solution of, 375 Snow Fairy Extract, 908 — Duodosalicylate, 846 — Imitation, 1168 — ■ Glycerophosphate, 846 — Top, 1031 — Lygosinate, 790 Snuff, Catarrh, 337 — ■ Pyrocatechin-Monacetate, 753 — Menthol, 337 — Salicylate Comp., Elixir of, 103 — Schneeberger, 337 Elixir of, 103 Snyder's All-Food Emulsion, 846 Solution of, 376 Soaps, 338, 339 — Santoninate, Troches of, 419 Soap, Arsenical, 1168 — Stearate, Solution of, 376 — Benzin, 1169 Suppositories, 396 — Bubble Liquid, 1168 — Sulfate, Effervescent Salt, 336 — Camphorated, Spirit of, 389 Exsiccated, 340 — Castile, White, 338 — — Glycerite of, 201 — Cleaning, 1169 Soft Soap, 338 — Comp., Liniment of, 230 Liniment of, 230 Pills, 302 Sohn's Wine Hypophosphites Comp., 847 — (Green) Tincture of, 503 — Wine Hypophosphites Comp., 728 — Liniment, 229 Solid or Dry Perfumes, 919 — Oxgall, 1169 Solidified Capaiba, 235 — Petroleum, 1169 — Gasoline, 1094 — Polishing, 1169 — Glycerin, 953 — Silver, 1169 Soluble Calomel, 696 — Solution of, 373 — Gun Cotton, 325 — Spirit of, 389 — Saccharated Iron, Syrup of, 420 — Stearin, 1169 — Silver, 709 — Whale Oil, 1170 — Tartar, 445 Soap Perfumes, 919 — Theocin, 859 Soap Plaster, 312 Solutions, 340-379 Soap Powders, 1182 Solution Anti-Phthisis. 847 Soap Bark, Fluidextract of, 178 — Bismuth and Hydrastia, 847 ——Tincture of. 503 and Hydrastia, 686 1246 INDEX. — Iodo-Bromide of Calcium Comp., 837 — Lactate of Strontium, 847 — Non Freezing, 1170 — of Bromids of Gold and Arsenic, Bar- clay, 678 and Calcium, 695 and Manganese, 793 Burdock, Comp., 847 Chloro-Phosphide of Arsenic, 847 Ferrous Malate, 847 Gold, Arsenic and Mercury, 794 — of Ginger, 123 — of Hvpophosphites, 847 Comp., 847 Lecithin, 847 Lime, 530 Pentaformates, 744 Solutol, 847 Solvasol, 847 — Lithium, 847 Solvent Mixture, 239 Solved, 847 Solurol, 847 Solykrin Pills, 847 Somatose, 847 Sommerbrodt's Creosote Capsules, 848 Somnal, 848 Somnin, 848 Somnoform, 848 Somnone, 848 Somnos, 848 Somnus Sedatus, 848 Sow Bread, Tincture of, 473 Soot, to Remove from Stovepipes, 1170 — (Wood) Ointment. 273 Soothing Ointment, 271 — Remedies, 587 Sophol, 848 Sorbefacin, 848 Soreness of the Feet of Dogs or Cats, 652 Soson, 848 Southern Cattle Fever, 631 Sownweed Compound, 848 Sozal, 848 Sozoiodol, 848 Spanish Fly, Tincture of, 463 — Leather, 924 Sparteine Sulfate, 849 Spasmotin, 849 Spavin Cures, 615 — Foot, Remedies for, 615 Spearmint Water, 532 Species, 579-381 Specific Medicines, 849 Spearmint, Spirit of, 389 — Tincture of, 504 Specific Tinctures, 475 Spencer's Chloramine Pastilles, 849 Spermaceti Cerate, 29 — Emulsion of, 121 — Ointment, 273 Spermine-Krieger, 849 — Poehl, 850 Spermin-Marpman, 849 Sphacelotoxin, 849 Sphygmogenin, 850 Spice- Bitters, 22 — Plaster, 305 — Poultice, 315 Spider Web, Tincture of, 503 Spigelia Powder Comp., 324 Spike, Oil of, 258 Spikenard Comp., Svrup of, 436 — Fluidextract of, 179 Spinatica, 850 Spino-Ferrinum, 850 Spinol, 850 Spirits, 381, 389, 898 Spirit of Almond, 898 Ambrette, 898 Bergamot, 898 Cedarwood, 898 Cinnamon, 898 Clove, 898 Hyacinth, 898 Lavender, 898 Lemon, 898 Lemon Grass, 898 Lilac, 898 Linaloe, 898 Mindererus, 34 Mycia, 916 Neroli, 898 Nutmeg, 898 Orange, 898 Orris, 898 Patchouly, 898 Pimento, 898 Rose, 898 Compound, 898 Geranium, 898 Sandol, 899 Vetivert, 899 Ylang-Ylang, 899 — Gums, 998 Spiritus Balsamicus, 19 Spiroform, 850 Spirosal, 850 Spleen Mixture, 246 Splenetic Mixture, 246 Sponges, Antiseptic, 389 Sponge, Burnt, Artificial, 389 — Carbolized, 390 — Tent, 390 — Tincture of, 503 Sponges, to Clean, 1170 Spring Flowers Extract, 909 Squanvine Comp., Elixir of, 79 Square Meal, 1031 Squibbs Alum Powder Comp., 316 — Cholera Mixture, 242 — Podophyllum or Laxative Pills, 302 — Solution of Opium, 369 Squill, Acetic Fluidextract, 179 — and Senega, Fluidextract of, 179 INDEX. 24' — Comp. Pills, 303 Syrup of, 437 — Extract of, 179 — Fluidextract of, 179 — Oxymel of 283 — Syrup of, 436 — Tincture of, 503 — Vinegar of, 522 (St. Germain Tea, 380 St. Ignatius' Bean, Extract of, 155 St. John Long's Liniment, 231 St. Johnswort Oil, 258 — Tincture of, 504 St. Victor's Balsam, 19 St. Yoes Ophthalmi Ointment, 270 Staffords Boro-Flourin, 850 Staggers, Remedies for, 615 Stagnin, 850 Stains for Wood, 1172 — to Remove from Fabrics, 1170 the Hands, 1172 Stamping Inks, 1117, 1175 Staphisagria, Fluidextract of, 179 Staphisagria, Tincture of, 504 Starch Gloss, 1175 — Glvcerite of, 201 — Iodid, Svrup of, 437 — Iodized, 390 — Mucilage of, 249 Stargrass, Elixir of, 54 — Fluidextract, 181 — Tincture of, 504 Startin's Mixture, 246 fStavesacre, Fluidextract of, 179 — Ointment, 273 — Tincture of, 504 Steagine, 850 Stearate of Morphine, 390 — of Zinc, 90 — Comp., 850 Stearns' Wine, 850 Steatins, 390 Stechkoerner Tinktur, 409 Steel Drops, 483 — Wine, 538 Stencil Ink, 1114 Stephanotis Extract, 909 Sterculia, Fluidextract of, 156 Steresol, 850 Stick Mustache Pomade, 997 — Pomatum, 997 — Salve, 586 Sticking Plaster, 312 Stigmata Maydis, Fluidextract of, 140 Stillingia Comp., Elixir of, 103 Fluidextract of, 1179 — Liniment of, 230 Syrup of, 438 Troches of, 519 — Fluidextract of, 179 — Syrup of, 437 — Tincture of, 504 Stilus Mentholi, 289 Stimulant Poultice, 314 Stimulating Liniment, 230 Stings and Bites, 587 Stoke's Expectorant, 243 — Liniment, 231 Stolen Kisses Extract, 909 Stomach Catarrh in Dogs and Cats, 653 Horses, 616 — Drops, 52, 459 — Inflammation of, in Cattle, 631 Stomachic Elixir, 92 — Tincture, 459 Stomalix, 851 Stomatol, 851 Stomosan, 851 Stone, Oil of, 252, 258 Stonebraker's Liniment, 851 — Pain Killer, 851 Stoneware Cement, 1059 Storage Batteries, 1176 Storax, Liquid, Purified, 390 — Prepared, 390 Stovaine, 851 Stovepipe Enamel, 1177 Stove Polish, 1176 Stramonium Comp., Ointment, 273 — Extract of, 180 — Fluidextract of, 180 — Infused, Oil of, 258 — Ointment, 273 — Poultice, 315 — Seed, Extract of, 180 — Seed, Fluidextract of, 180 — Seed, Tincture of, 504 — Tincture of, 504 Strangles, Remedies for, 616 Strawberrv Cold Cream, 938 — Cream, "938 ' Puff, 1031 — Lotion, 951 Straw Hat Cleaners, 1177 Varnish, 1177 Strengthening Plaster, 307, 312 — Syrup, 438 Streptocol, 851 Strophanthin, 851 Strophantus, Extract of, 180 — Fluidextract of, 180 — Lactate, Solution of, 376 — 'Tincture of, 504 Strontium Bromide, Solution of, 376 Strychnine Acetate, Solution of, 376 — Comp, Tincture of, 505 — 'Extractum, 167 — Hvdrochlorid, 377 — Nitrate, Solution of, 377 — Ointment, 273 — Oleate, 279 — Valerianate, Elixir of, 104 — Solution of, 376 — Tincture of, 505 Strzvzowski's Mixture, 851 Stypticin, 852 1248 INDEX. Styptic Balsam, 232 Sulphoguaiacin, 853 — Collodion, 35 Sulphonal, 853 — Cotton, 44 Sulphonethylmethane, 864, 853 — Powder, 325 Sulphonmethane, 853 Styptol, 852 Sulphydrol, 853 Styracol, 852 Sultana Cold Cream, 938 Styrax, Syrup of, 438 Sulzburger Fluss Tinktur, 853 Stuart's Calcium Wafers, 851 Sumach, Fluidextract of, 174 — Dyspepsia Tablets, 851 — Tincture of, 506 Subcutin, 852 Sumbul and Ammonium Valerianate, Subeston, 852 Elixir of, 104 Sublamine, 852 — Elixir of, 104 Sublimated Catgut, 27 — Comp., Elixir of, 104 — Cotton, 43 — Extract of, 180 — Gauze, 192 — Pills, 303 — Jute, 220 — Tincture of, 505 — Silk Ligature, 337 Sun Cholera Mixture, 242 Succus Alterans, 852 Sundhed's Salt, 334, 853 Sucramine, 852 Sunflower Comp., Syrup of, 438 Sucrol, 722, 852 — Syrup of, 438 Sudorific Tincture, 502 Sunstroke, 588 Suet, Prepared, 391 — in Horses, 617 — Salicylated, 391 Suppositories, 392-400 Sugared Calamus, 37 Sulfanilic Acid, 852 Suprarenal Liquid, 853 Suprarenalin, 853 Sulfate of Iron, Dried or Exsiccated, 217 Suprarenin, 854 Sulfogen, 853 — Borate, 854 Sulfogenol, 853 Surgeon's Antiseptic Oil. R^& Sulfophenate, 695 — Lubricant, 234 Sulfosalicvlic Acid, 852 — Soap, 338 Sulfosot, 852 Surgical Soap, 338 Sulphur and Cream of Tartar Powder, Svapnia, 854 325 Swedish Balsam, 19, 458 — Balsam of, 20 — Bitters, 91 — Bath Salt, 1018 — Blood Purifying Tea, 379 — Black, 391 — Cholera Mixture, 242 — Compound Tablets, 853 Sweeping Compounds, 1178 Lotion, 234 Sweet Brier Extract, 909 — Confection of, 39 Sachet, 924 — Depuratum, 392 — Clover, 1031 — Hepar, 24 — Flag, Extract of, 136 — Hypochlorite Ointment, 274 Fluidextract of, 136 — Iodid, 391 — i — Tincture of, 462 Ointment, 274 — Gum, Syrup of, 438 — Lotum, 392 — Hawthorne Extract, 909 — Ointment, 273 — Pea Extract, 909 — Ointment, Alkaline, 273 — Spirit of Nitre, 386 — Ointment Comp., 273 — Sumach, Fluidextract of, 174 — Ointment, Red, Lassar's, 274 — Sumach, Tincture of, 506 — Precipitated, 391 — Vernalia > Extract, 909 — Spirit of, 505 Swine Medicines, 642 — Strips, 1178 Sydenham's Laudanum, 493 — Tincture of, 505 Sycose, 854 — Troches, 519 Sympathetic Inks, 1115 — Washed, 392 Symphorol, 854 Sulfurated Lime, Solution of, 377 Synthetic Hair Dyes, 995 — Oil, 20 — Perfumes, 887 — Potassa, 313 — Preparations, 659 Sulfuric, Acid, Aromatic, 15 Syphilis Remedies, 589 Mixture, 246 Syrocolin, 854 Ointment, 274 Svrquin, 854 Sulfurous Acid, 15 Syrups, 400-444 Sulphaniniol, 853 Syrup Antiepischesis, 854 INDEX. 1249 — Cannabis Comp., 854 Tanphenyform, 857 — Cocillana Comp., 855 Tan Shoe Dressing, 1159 — Codeine Comp., 855 -^ Tan Shoes, to Blacken, 1161 Phosphate Comp., 855 Tansy, Comp., Tincture of, 506 — Iron Chloride, Weld, 855 Tape Worm Remedies, 589, 594 — Lactopeptine with Phosphates, 855 Tar, Alkaline Solution of, 377 — Laxatans, 855 — Compound, Elixir of, 104 — Manganum Comp., 855 — Glycerite of, 201 — of Acid Glycerophosphates, 854 — Infusion of, 210 the Mineral and Alkaloid Hypo- — Mixture, 247 phosphites, 769 — Oil, Mixture, 247 — Phospho-Chloride Iron, 855 — Ointment, 274 — Phytolacca Comp., 855 Comp., 274 — Pinus Alba Comp., 855 — Plaster Comp., 313 — Potassium Hypophosphite, 855 — Shampoo Liquid, 976 — Pulmonic Compound, 855 — Stains, to Remove, 1178 — Roborans, 855 — Syrup of, 436 — Sanguinaria Comp., 855 — Water, 210, 532 — Seven Hypophosphites, 855 — Wine of, 541 — Six Hypophosphites, 856 Taraxacum Comp., Elixir of, 104 Syrupus Domesticus, 403 — Extract of, 147 — Laxative Mixture, 247 Tableau Lights, 1133 Tartar Emetic Ointment, 260 Table Tops, to Make Acid Proof, 1178 Tartarlithine, 857 Tablet or Frozen Perfume, 926 Tartar Soluble, 445 Tablets, 514 Tartrate of Iron and Potassium, 216 — Antiseptic, 444 Tasteless, Liquid Extract of Cascara — of (Artificial) Vichy Salt with Lith- Sagrada, 140 ium, Effervescing, 445 — Quinine, 742 — Plasma, Nasal, 445 — Tincture of Chlorid of Iron, 484 Tabsoids, 856 Tattoo Marks, to Remove, 1178 Tabsules, 856 Taylor's Lotion, 234 Tachiool, 856 Tea, Fluidextract of, 181 Taka-Diastase, 856 Tebecin, 858 Talc, Purified, 445 Teething Necklaces, 858 Tallow, 391 — Remedies, 587 Tallows, 445 Telephone Solution, 1178 Tamar Indien, 856 Tenaline, 858 Tamarind, Extract of, 181 Terebene, 858 — Pulp, Purified, 325 Teremorrhu, 858 Tamarinds, Essence of, 124 Terpeneless Oils, 886 — Syrup of, 438 Terp-Heroin, 858 Tannal, 856 Terpin Hydrate, Elixir of, 105 Tannalbin, 856 and Codeine, Extract of, 105 Tannalborin, 856 and Heroin, Elixir of, 105 Tannated Collodion, 35 Terpineol, 888 Tannic Acid, Glycerite of, 202 Terpinoids, 858 Ointment, 274 Terrol, 858 Suppositories, 399 Testaden, 858 Troches, 520 Testine, 858 Tannigen, 856 Teston, 858 Tannin Collodion, 35 Tetraethylammonium Hydroxid, 858 — Gargle, 590 Tetraiodoethylene, 720 — Gauze, 194 Tetraiodophenolphtalein, 673 — Milk Albumose, 782 — Suppositories, Urethral, 400 Tetraiodphenolphtalein-Bismuth, 734 Tetranitrin, 731 Tannisol, 857 Tetranitrol, 731 Tannobromine, 857 Tetriodophyrrol, 774 Tannoform, 857 Tetronal, 858 Tannone, 857 Tetter, in Cattle, 632 Tannopine, 857 Texas Fever, 632 Tannothymol, 857 Thalictrum Anemonoides Fluidextr:u\ Tanosol, 857 of 175 1250 INDEX. Thalline Sulfate, 858 — Tincture of, 455, 506 Theatrical Cold Cream, 938 Thymacetin, 861 Thebracum, Tincture of, 491 Thymenthol, 861 Theegenische, 379 Thymidol, 861 Thee Kraenter, 379 Thyminic Acid, 861 Theine, 859 — Tablets, 861 Theobroma Cold Cream, 937 Thymiodide, 861 — Tincture of, 461 Thymoform, 862 Theobromine, 859 Thymol Carbonate, 862 — and Lithium Benzoate, 859 — Cotton, 45 — and Lithium Benzoate, 870 — Dry, 450 Salicylate, 870 — Gauze, 194 — Sodium Acetate, 664, 359 — Iodid, 450 Citrate, 859 — Mouth Wash, 1015 Salicylate, 721, 859 — Ointment, 274 Theocin, 859 — Salicylate, 839 — Sodium Salicylate, 859 — Tooth Paste, 1010 Acetate, 859 Powder, 1007 Theolactine, 859 — ■ Trichloracetate, 861 Theonacet, 859 — Water, 532 Theophyllin, 859 Thymoloform, 862 Thephorin, 859 Thymolyptol, 862 Therapogen, 859 Thymoxol, 862 Theriac, 38 Thymotal, 862 Thermiol, 860 Thymoxal, 862 Thermodin, 860 Thyptol, 862 Thermofuge, 860 Thyraden, 862 Thermol, 860 Thyroid Solution, 377 — Salicylate Comp., 860 Thyroiodin, 775, 862 Thial, 860 Thyroidinase, 862 Thiderol, 860 Thyro-Iodose, 862 Thielemann's Cholera Mixture, 242 Thyreoidectin, 862 Thiersch's Antiseptic Solution, 345 Tick Fever, 632 Thieucalyptol, 860 — Powder, 650 Thigenol, 860 Tiglium Collodion, 34 Thilanin, 860 Tilia, Tincture of, 487 Thiocol, 860 Tilly Drops, 256 Thiodine Suppositories, 860 Tincture Aromatica Acida, 15 Thioform, 861 — of Ambergris, 899 Thiol, 861 Ambretta, 899 Thiolan, 861 Artificial Civet, 899 Thioresorcin, 861 Artificial Musk, 899 Thiosinamine, 861 Civet, 899 Thomas' Eye Water, 861 Musk, 899 Thomsonian Remedies and Prepara- Orris, Stronger, 899 tions, 445 Weaker, 899 Thompson's Solution of Phosphorus, — ■ — Siam Benzoin, 899 370 Storax, 899 Thomson's Salve, 265 Tolu, 899 Thoroughpin, Remedies for, 617 Tonka, 899 Thoroughwort, Fluidextract of, 134 Vanilla, 899 Thousand Flowers, 906 — Passiflora, 862 Three Bromids, Elixir of, 64 — Purgans, 485 — Chlorides, 861 — Senna Comp., 716 ■ Elixir of, 68 Tinctures, 450, 899 — Phosphates, Elixir of, 87 Tire Cement, 1059 — Valerianates,' Elixir of, 105 Tisanes, 511 Throat Affection, For, 589 Tissue Flood, 862 — Inflammation of, in Cattle, 633 Tittman's Purgative Pills, 862 Thrush in Calves, 633 Tobacco Antidote, 591 Sheep, 641 — Extract of, 181 — Running, Remedies for, 618 — Ointment, 274 Thuja Occidentalis, Elixir of, 58 — Tincture of, 506 INDEX. 1251 — Water, 532 Tobias' Derby Condition Powder, 862 — Venetian Ointment, 862 Horse Liniment, 862 Toilet Aromatic Vinegars, 917 — Articles, 881 — Creams, 943 Containing Irish Moss. 946 Linseed, 945 Quince Seed, 945 Tragacanth, 944 — Jellies, 952 — Lotions, 950 — Milks, 949 — Oatmeal, 957 — Pomades, 955 — Powder, 963 — Waters, 912 Tolu, Ethereal Tincture of, 506 — Fluidextract of, 181 — Soluble, Fluidextract of, 181 Tincture of, 506 — Syrup of, 439 — Tincture of, 506 — Water, 532 Toluol, 863 Toluene, 863 Tolyantipyrine, 863 Tolypyrine, 863 — Salicylate, 863 Tolysal, 863 Tongaline, 863 — Tablets, 863 Tonic Aphrodisiac Tablets, 863 — Bath Salt, 1018 — Beef, 863 — Compound Mixture, 247 — Hypophosphites, 863 — Medicine for Birds, 656 for Dogs and Cats, 653 — Nervine Tablets, 863 — Pills, 303 — Phosphates, 863 — Shampoo Liquid, 976 Tonics, 511, 591 Toning Solutions, 1179 Tono Sumbul, 863 Tonols, 863 — and Mouth Preparations, 1002 — Cements, 1179 — Creams and Pastes, 1007 — Paste Flavors, 1008 — Pastes, 1007 — Powders, 1002 — Soaps, 1010 — Washes, 1011 Toothache Remedies, 591 Toril, 863 Townsend's Pills, 303 Toxicodendri, Tincture of, 496 Tracing Paper, 1179 Tragacanth, Glycerite of, 202 — Mucilage of, 249 79 — Powder Comp., 325 Trailing Arbutus Comp., Infusion of. 210 Extract, 909 Transfusion Fluids, 512 Transparent Pomades, 981 Traumatic Balsam, 19 — Elixir, 19 — Elixir, 458 Traumaticin, 357, 863 Trecarnol, 888 Traumatol, 863 Trefle Extract, 909 Trefol, 888 Triacol, 863 Triberane, 863 Tribromanilin Hydrobromid, 690 Tribromhydrin, 667 Tribromphenol, 692 Tribromphenol-Bismuth, 877 Trichloracetic Acid, 864 -Tri-Chloramido-Ethylic Alcohol, 704 Trichlor-Isoproyl Alcohol, 777 Trichophytin, 864 Tricresote, 823 Tri-Ferment Comp., 864 Triferrin, 864 Triferrol, 864 Trifolin Fibrini, Extract of, 134 Trifolium Comp., Syrup of, 439 — Pratense, Tincture of, 498 — Repeus, Tincture of, 469 Trigemin, 864 Tri-Iodo-Cresol, 789 Triiodometacresylic Acid, 789 Trikresol, 864 Trikresolamine, 780, 864 Trillium, Fluidextract of, 132 Trinitrin, 385, 864 — Tablets, 444 Trinitrophenol, 824 Trional, 864 Triosine, 864 Triotonol, 864 Trioxymethylene, 865 Tripartol, 865 Triphenin, 865 Triple Bromide, Elixir of, 64 — Phosphates, Elixir of, 87 — Valerianates, Elixir of, 105 Triplex Pills, 303 Tritica, 865 Triticum, Extract of, 146 — Tincture of, 472 Tritipalm, 865 Tritols, 865 Triturations, 512 Troches, 514 Tropacocaine Hydrochlorid, 86b Trophonine, 865 Tropon, 865 Trousseau's Diuretic Wine, 537 Trousseau's Diuretic Wine. 865 1252 INDEX. Trumatol, 714 Trygase, 865 Trvpsin, 865 — Glycerole, 866 Trypsogen, 866 Tuberculin, 866 Tuberculocidin, 866 Tuberose Extract, 910 Tubocurorine, 715 Tuklin, 866 Tulase, 866 Tully's Powder, 322 Tumenol Oil, 867 — Paste, 866 — Powder, 867 — Sulfonic Acid, 867 — Venale, 866 Tumenole Ammonium, 866 Turck's Compound Emulsion, 867 Turicin, 867 Turkey Corn, Compound Elixir of, 74 Syrup of, 407 Fluidextract of, 181 Tincture of, 472 Turkish Punch, 1031 --Sherbet, 1031 Turlington's Balsam, 19, 458 Turmeric Paper, 285 Turnera, Elixir of, 74 — Fluidextract of, 147 — Tincture of, 507 Turner's Cerate, 27, 261 Turpentine Anodyne Solution, 378 — Balsam of, 20 — Confection of, 39 — Liniment, 231 Acid, 231 — Ointment, 275 — Oil, Emulsion of, 121 Stronger, Emulsion of, 122 Tincture of. 507 — Rectified, Oil of, 258 — Venice, Factitious, 520 — and Acetic Acid, Liniment of, 231 Turunda, 232 Tussiculin, 867 Tussol, 867 Tutti Frutti, 1032 Tutulin, 867 Twigg's Hair Restorer, 990 Two Chlorids, Elixir of, 68 Tyalid, 867 Tympanitio in Cattle, 633 Sheep, 641 Tyndale's Compound Syrup of Euca- lyptus, 867 Typewriter Ink, 1118 — Ribbons, 1179 Tyree's Antiseptic Powder, 867 Tyree's Buchu and Hyoscyamus Comp., 867 Tyree's Hypophosphatite Powder Comp., 867 Udder, Inflammation of, 634 Ulmarine, 867 Ulvptol, 735, 868 Unada. 868 Unger's Cure for Drunkenness, 868 Ungrol, 868 Unguenta Extensa, 390 Unquentine, 868 — Cones, 868 — Crayons, 868 — Pessaries, 868 Unquentum Crede, 868 — Betulae Comp., 868 — Cerussae, 266 — Crede, 710 — Egyptiacum, 231 — Fuscum, 27, 261 — or Linimentum ad Decubitun Auten- riethic, 223 L'nicorn Root, Elixir of, 54 — — Fluidextract of, 181 Universal Balsam, 20 — Plaster, 310 Unna's Spiritus Capillorium, 985 Uraline, 868 Uralium, 868 L'ranium Nitrate, 868 Urasol. 869 Urea, 869 Urethane, 869 Urethral Injection, 212 Urgosan, 869 Uriscol, 869 Uric Solvent, Havden's, 869 Uriform, 869 Urinarv Disease in Horses, 618 Urine, Bloody, in Cattle, 634 in Sheep, 641 — Retention of, in Sheep. 641 L T riseptin, 869 Uritone, 869 L'rocitral, 869 Urocol, 869 Uroformin, 869 — Comp. Elixir, 869 Urol, 869 Urolvsin, 869 Uropherin-B. 870 L>opherin-S, 870 Uropurgol, 870 Uropurin, 870 Urosine. 870 L'rotropine, 870 Urotropin Quinate, 704 — Quinate. 870 — Salicylate, 838 — Tannate, 870 Ursin, 870 Urtica, Fluidextract of, 167 L'riptamine, 870 Ustadine. 870 Ustilago Maidis. Tincture of, 471 Uterine Tonic Sedative, 870 INDEX. 1253 Sedative, 728 Veratrone, 872 Utero-Tonic Cordial, 747 Veratrum Fluidextract of, 182 Uterol, 870 — Tincture of, 508 Uterotonic Compound, 870 — Viride, Fluidextract of, 182 Utonia, 870 Ointment, 265 Utros, 870 Tincture of, 508 Uva Ursi, Extract of, 182 Verbascum, Fluidextract of, 166 Fluidextract of, 182 Verbena Extract, 910 Infusion of, 210 — Fluidextract of, 182 — Sachet, 924 Vaginal Pessaries of Solidified Glycerin, — Water, 916 794 Verdigris Liniment, 231 — Wafers, 871 Vereform Antiseptic, 872 Vaginoids, 871 Vermifuge Oil, 245 Vagipos, 871 Vermifuges, 593 Valangin's Arsenic Solution, 345 Vermifugin, 872 Valerian, Ammoniated, Tincture of, 508 Vermin Destroyers, 595 — Comp., Infusion of, 210 Veroform Germicide, 872 Pills of, 303 Veronal, 873 — Ethereal Tincture of, 508 Veronica Extract, 910 — Fluidextract of, 182 Vervain's Balsam, 19 — Tincture of, 507 Vervain, Fluidextract of, 182 — Volatile Tincture of, 508 Vesicating Collodion, 34 Valerianate of Iron, Elixir of, 88 — Paper, 284 Quinine and Zinc, Elixir of, 105 Vesipyrin, 873 Zinc, Elixir of, 106 Vestosol, 873 Validol, 871 Veterinary Preparations, 597 — Camphorated, 871 Vial's Capsules of Oil of Juniper, 873 Vallet's Moss, 236 Viburnal, 873 Vanilla, Essence or Extract of, 508 Viburnum Comp., Pills of, 303 Valofen, 871 Tincture of, 509 Valyle, 871 — Opulus, Comp., Elixir of, 74 Vanadium Ink, 1110 Fluidextract of, 147 Vanier's Iodized Syrup Quinine, 871 — Prunif, Elixir of, 63 Vanilla Puff, 1032 Fluidextract of, 133 — Tincture of, 508 Vibutero, 873 Vanillin, 887 Vichy, Effervescent Salt, Artificial, 336 — Comp., Essence of, 508 — Salt, Artificial, 335 Van Srvieten's Solution, 367 — Salt with Lithium, Effervescing Tab- Van's Mexican Hair Restorative, 871 lets, 445 Vapors, 210-211 — with Lithium, Effervescent Salt, Arti- Varalettes, 871 ficial, 336 Varnishes, 1179 Vienna Caustic, 27 Varnish Removers, 1142 — Draught, 209 Varnishes, Skin or Dermatic, 520 — Paste, 287 Vanishing Inks, 1115 Viferral, 873 Vaseline Emulsion, 871 Villate's Solution, 378 Vasenol, 872 Villosa Compound, 873 Vasogen, 872 Vindone, 873 Vasopolentum, 872 Vinegars, 522 Vegetable Cathartic Pills, 294 Vinegar, White Wine Imitation, 523 — Powder, 318 Vinette, 873 Veilchen Sirup, 439 Vin Nourry Iodotane, 873 Velpeau's Black Caustic, 27 Vinopyrim, 873 — Cholera Mixture, 243 Vinum Amarum, 792 Venice Turpentine, Factitious, 520 Vinum Malti et Cinchonae Ferratum, Veracolate, 872 792 Vera Diastase, 872 Vioform, 873 Essence, 872 — Gauze, 873 Veratrine, Glycerite of, 202 Viola Cream, 873 — Ointment, 275 Violade. 1032 — Oleate, 280 Violet, 926 Veratrol, 872 — Ammonia, 1019 1254 INDEX. -de Parme Extract, 910 — Extract, 910 — Inks, 1110 — Lotion, 1019 — (Forest) Extract, 910 — (Imperial) Extract, 910 — (Mountain) Extract, 910 — Mouth Wash, 1015 — (Riviera) Extract, 910 — (Russian) Extract, 910 ■ — Sachet, 924 — Smelling Salts, 928 — (Spring) Extract, 911 — (Swiss Alpine) Extract, 911 — Syrup, 439 — Talcum Powder, 965 — (Tampa) Extract, 911 — Toilet Cream, 947 — Toilet Powder, 965 — Tooth Powder, 1007 — Water, 916 — Witch Hazel, 917 — (Wood) Extract, 911 Violin Varnish, 1182 Virginia Creeper, Tincture of, ^454 — Snake Root, Fluidextract of, 178 Infusion of, 209 Tincture of, 501 — Prune, Syrup of, 441 Tincture of, 510 Virilin, 874 Virol, 874 Viscerale Hoffmanni, Elixir, 92 Viscin, 874 Viscolan, 874 Viskolein, 874 Vitalic Hypophosphites, 874 Vitelli, Glvcerite of, 202 Vitose, 874 Vitriol, Elixir of, 15 Vleminck's Solution or Lotion, 377 Volatile Liniment, 225 — Oils, Emulsion of, 122 — Salts, 336 — Tincture. 509 Volesan, 874 Volkman's Antiseptic Liquid, 345 Voseptol, 874 Vulneral, 874 Vulnoplast, 874 Wade's Balsam, 19, 458 Wafer Ash, Elixir of, 106 Wine of, 541 Wahoo, Elixir of, 106 — Extract of, 182 — Fluidextract of, 182 — Tincture of, 509 "W-A" Intestinal Antiseptic, 874 Wall-Paper Cleaner, 1182 Walnut Hair Oil and Dye, 995 Wampole's Antiseptic Solution, 744 — Antiseptic Solution, 874 — Preparation of Cascara Bark, 874 — Preparation of Extract of Cod Liver, 874- Warburg's' Pills, 293, 303 — Tincture, 455, 510 Ward's Essence for Headache, 875 — Paste, 287 Warner's Gout Cordial, 500 Warming Plaster, 311 Warren's Antidiphtheritic Mixture, 239 — Inhalation, 211 — Styptic, 232 Wart Eradicators, 595, 972 Washed Sulfur, 392 Washes, 523 Washing Fluids, 1182 — Powders, 1182 Watchmakers' Oil, 1183 Water, 523 — Pepper, Tincture of, 502 Waterbury's Cod Liver Oil Compound, 875 Waterhouse Uterine Wafers, 875 Waterproof Cement, 1059 Waterproofing Cloth, 1183 — Paper, 1184 Waters, Aromatic, 890 — Medicated, 526 Watt's Anti-Rheumatic Pills, 875 Wax, Emulsion of, 123 — Ointment, 275 — Paste, 287 — Yellow, Filtered, 532 Waxham's Tonic Pills, 875 Wayne's Aphrodisiac Tablets, 875 Weber's Alpine Tea, 875 Wedell's Tincture, 511 Weeks' Anti-Constipation Pills, 875 Wedgewood Mortars, to Repair, 1184 Weed Killers, 1184 Weinmann's Dental Anaesthetic, 875 Weisse Mutterkramptropfen, 52 — Quicksilver Salbe, 260 Weisser Syrup. 436 Weld's Syrup of Iron Chlorid, 875 West End Extract, 911 Westphal's Auxiliator, 875 Wheeler's Nerve Vitalizer, 875 — Tissue Phosphates, 875 Whisker Dyes, 991 White Arquebusade, 18 — Ash, Wine of, 542 — Glycerin, 951 — Hellebore Ointment, 265 — Ink, 1110 — Lead Plaster, 309 — Liniment, 231 — Liquid Physic, 290 —Lotion, 234 — Mother Drops, 385 — Oak. Fluidextract of, 182 — Oil Stock Liniment, 612 — Oils, 231, 259 INDEX. 1255 — Pine Comp, Elixir of, 106 Fluidextract of, 183 Syrup of, 440 Cough Syrup, 441 — Pond Lily Extract, 905 — Precipitate Ointment, 260 — Rose Cologne, 914 White's Eye Water, 876 — Salve, 876 Whitehead's Spirit of Mustard, 876 White Wash, 234 Whitewash, 1184 White Wine, Stronger, 542 Vinegar, Imitation, 523 Whooping Cough Remedies, 568 Wickersheimer's Preservative Fluid, 876 Widow McPhelan Extract, 911 Wiener Frank, 209 Wiesel's Vin Kollerina Comp, 876 Wild Cherry and Morrhualine Cordial, 876 Comp., Syrup of, 441 Comp. Syrup, 566 Detannated, Fluidextract of, 184 Elixir of, 106 Ferrated Wine of, 542 Fluidextract of, 183 for Syrup, Fluidextract of, 184 Infusion of, 210 Syrup of, 441 Syrup, 1032 Tincture of, 510 Wine of, 542 — Flowers Sachet, 924 — Indigo Comp, Pills of, 303 Ointment, 275 Poultice, 315 Tincture of, 510 — Olive Extract, 911 — Pine, Inhalation of, 211 — Yam, Troches of, 520 Wilkinson's Ointment, 273 William's Aphroditic Lymph, 876 — Flour Paste, 1138 Wilson's Ointment, 275 Winchell's Paste, 1059 Wind Pulver, 320 — Wasser, 526 Window Polishes, 1185 Windows, to Prevent Frosting and Steaming, 1184 Wines, 532, 542 Wine Bitters, 537 — Oil of, 254 — of Cod Liver Oil Comp, 876 Extract with Cherry and Hypophosphites, 876 Extract with Peptonate of Iron, 876 Hypophosphites Comp, 876 Mitchella Comp, 876 Senecio Comp, 876 Wintergreen, Spirit of, 389 Wismol, 876 Wistar's Cough Lozenges, 877 Witch Hazel Cold Cream, 938 — Distilled Extract of, 184 — Jelly, 953 — Lotion, 951 — Ointment, 275 — Salve, 586 — Tincture of, 510 — Toilet Cream, 947 Wither's Antizymotic Solution, 877 Wlinsi's Paper, 877 Woman's Friend, 22 Womb, Inflammation of, in Sheep, 642 Wood Floors, Polishing, 1185 — Species, 381 — Stains, 1185 — Stains, 1172 — Wool, 542 Sublimated, 542 Wood's Cough Mixture, 567 — Red Tonic, 512 Woodbine Extract, 911 Woodbridge, Treatment of Typhoid Fever, 877 Wool Fat, 543 Ointment, 275 Worden's Nasal and Throat Spray Geolinum Antisepticum, 877 Worm Medicines, 596 — —for Dogs and Cats, 653 Swine, 646 — Mixture, 247 — in Horses, 618 — Remedies for Cattle, 635 Wofmseed Mixture, 247 — Tincture of, 510 Wormwood Comp, Tincture of, 510 — Tincture of, 510 Wounds on Cattle, 635 Wright's Condensed Smoke, 877 Wrinkle Cream, 971 — Lotion, 971 Wund Balsam, 19 — Wasser, 18 Wunder Kronesseus, 91 Wyeth's Effervescing Headache, 877 Xanol, 877 Xaxa, 877 Xeroform, 877 Xylene-Dimethylbenzene, 878 Xylol, 878 Yabarra Chocolate, 1032 Yale's Hair Tonic, 878 Yara, 889 Yeast Poultice. 315 Yellow Dock Comp, S} r rup of, 441 ■ Fluidextract of, 185 — Jessamine, Tincture of, 475 — Lotion, 234 — Mercuric Oxid Ointment, 269 — Ointment, 267 125G IXDEX. — Parilla, Fluidextract of, 185 — Dermatol Paste, 288 — Pills, 292 — Gelatin, 195 — Wash, 234 — Gelatole, 196 — Wax, 532 — Glvcerogelatin Ferin, 202 "Soft, 202 Yerba Mausa, Fluidextract of, 185 — Glue, 196 Yerba Santa and Licorice, Syrup > of, 443 — Iodid, Svrup of, 414 Concentrated, Syrup c f, 444 — Jelly, 195 Aromatic, Elixir of, 107 — Oil Paste, 288 Aromatic, Fluidextract of, 185 — Ointment, 276 Syrup of, 442 — Ointment Comp., 275 Comp., Elixir of, 107 Mild, 275 Cough Mixture, 566 — Oleate, 280 Elixir of, 107 Ointment, 276 Fluidextract of, 185 — Oleo Stearate of, 280 Licorice and Chocolate Comp., — Oxid Ointment, 276 Syrup of, 443 Ointment Comp., 276 Syrup of, 441 — Paste, Lassair, 287 Ylang Ylang, 889 Soft, Unna's, 288 Extract. 911 — Perhydrol, 878 Oil of, 889 — Permanganate, 878 -Sachet, 924 — Stearate, 390 Yohimbine, 878 Ointment, 276 Yolk of Egg, Glycerite of, 202 — Sulfate Comp., Urethral Supposi- tories, 400 Zaza's Toilet Cream, 878 Ointment, 276 Ze-An, 878 — Sulf ocarbolate, 878 — Forminated, 878 Gauge, 194 — Lithiated, 878 — Sulfur Paste, 288 Ze-Aseptine, 878 Zinol, 878 Zedoary, Bitter Tincture of, 510 Zittmann's Weaker or Milder Decoction — Comp., Tincture of, 511 48 Zeltchen, 514 — Decoction, 48 Zemacol, 878 Zollickoffer's Mixture, 247 Zepp's Dandruff Cure, 878 Zoll's Pink Paste, 288 Zinc Acetate Pills, 304 Zomol, 879 — and Aluminum Comp., Solution of, Zoa-Phora Remedies, 879 378 Zoolak, 879 — and Iron Comp., Solution of, 379 Zucker Sirup, 436 — Carbonate Cerate, 27 Zumo-Anana, 879 — Carbonate Ointment, 261 Zymin, 879 — Chlorjd, Solution of, 378 Zymocide, 879 — Coloring, 1185 Zvmoidin, 878 — Comp., Lotion, 234 Zymphene, 879 752 N ' %/ ,# / - V ,\A A ^•%\} t ^// v o ^ ^ - &° ^ . ^- -,r, .\V \ v it, v V" > lilillf