RHAZES -Abu Bakr Muhammad ibn Zaka-riya al-Razij, 8507-925? De Variolis et Morbillis. Treatise on the Small Pox Tr. into English by Thomas ag 5) and Measles. ( D Stack, for Richard Mead ; and ed., 1755.) { Tn no, 3366, pp. 111-204. & Ee ’ P : 3366. The same. A Discourse on the Small- Pox and Measles. To which is annexed, A treatise on the same diseases, by... Abu Beker Rhazes. The whole tr. into English, under the Author’s inspection, by Thomas Stack. 2nded. 8°. Lond., 1755. ri The Rhazes is catalogued as nos. 456-7. FROM LIBRARY OF SIR WILLIAM OSLER, Barr. THE OXFORD FROM THE LIBRARY OF SIR WILLIAM OSLER, Bart. OXFORD 7S" A DISCOURSE SMALL POX M E A S-L.ES. RICHARD MEAD, Fellow of the Royal Colleges of Phyficians at London and Edinburgh, and of the Royal Society ; and Phyfician to His Majesty. . To which is annexed, A TREATISE on the fame Difeafes, by the celebrated Arabian Phyfician ABU- BEKER RHAZES. The Whole tranflated into Englifb, under the Author’s Infpeétion, By THOMAS STACK, M.D, F.R.S. SECOND EDITION. oe L Qo NON: Printed for J. BR rN DLE Y, Bookfeller to his late Royal Highnefs the Prince of Wales, in New Bond= Street, M.DCCLY. PREFACE. Confiderable part of this Dit courfe was written by me ma- ny years fince; and the whole had been finifbed and given to the Public long ago, would the bufine/s of my profeffion, in which I have been conftantly engaged, have allowed mé time to do it. However, I flatter myfelf, that this intermiffion of the work will in the main turn to the ad- vantage of the reader : because what- ever inconveniencies may attend age, they are for t® moft part amply compenfated by daily acquifitions of knowledge and experience. Where- fore, without farther apology, I foall now briefly lay down the motives, which firft induced me to write on this fubjett. . Az fn iv PREFACE, Iv the year 19717 the learned Do&for Freind publifbed the fart and third books of Hippocrates’s Epi- demics, ilujirated with nine Com- mentaries concerning Fevers. Of thefe the feventh treats of purging in the putrid fever, which follows upon the confluent Small Pox; and in fupport of his opinion, he has an- nexed to it the letters of four phyf- cians to himfelf on that fubjeét ; one of which is mine. For after having been feveral years one of the phy ficians to St.’'Thomas’s Hofpital, iz the year 1708, I obferved, that [ome of my patients recovered from a very ma- hignant fort of Small Pox, even be- yond expettation, by a loofene/s feiz- ing them on the ninth or tenth day of the difeafe, and fometimes earlier. Hence I took the hint, ta try what good might be done by opening the body with a gentle purge on the de- cline rR HE FA GSE: Vv cline of the diftemper, efpécially where the patient had conftantly been coftive from the beginning ; which is far from being an uncommon cafe. The fucce/s was in a great meafure anfwerable to my wifbes : for by this method I recovered many, who were in the moft tnminent danger. Ar that time, and indeed during the remainder of his life, I was ftrit- ly joined in friendfbip with Dr. Freind ; and as we frequently con- verfed on the bufine/s of our profe/- fron, Lexplained this point of prattice to him, and met with his approba- tion. Soon after this, Ae was called to a confultation with two other emi- nent phyficians, on the cafe of a_young nobleman, who lay dangeroufly ill of the Small Pox : whereupon, he pro- pofed my method. But they obftinate- ly oppofed it until the fourteenth day from the eruption, when. the cafe ap- peering Vi PREFACE. pearing quite defperate by convulfr- ons with a lethargy coming on apacey they confented to give him a gentle laxative draught 5 which had avery good effec. Hereupon Dr. Freind gave his opinion to repeat it; but that was over-ruled, and the patient died the feventh day after. The doétor himfelf has given an ample. account of this cafe (1.) Tus affair foon made fo great a noife, that even the gentlemen of the faculty were divided upon it , fome commending, others finding fault with Dr. Freind’s advice: which fo effen- tially affeéted his reputation, that be thought himfelf under a necefity of vindicating it: and therefore he en- treated me to fend him the purport of our former converfation in writing. Such was our friendfbip, that I foon (1) Freindi Opera, p. 263. complied rae. PA CE, Vii complied with his requeff; and he foewed my letter to Dr. Radcliffe, (who at that time was very deferved- ly at the head of his profeffion, upon account of his great medical pene- tration and experience, and had ho» noured me with a confiderable fhare of intimacy) and toldhimwithal, that he intended to publifo bis Defence. Whereupon, Dr. Radcliffe obtained leave of me for Dr. Freind to annex my letter to his book. But after two or three foeets had been printed off, he was prevailed on by Jome friends to drop his undertaking ; and thus both his work and my letter lay by for fome years, that is, until he publifbed his Commentaries on fevers. Whilehewas employed in this work, he had frefh thoughts of printing the aforefaid let~ ter with it ; for which purpofe, I re- vifed and enlarged the letter, tran- plated it from the original Englith into Latin, and, in fhort,new-2modelled 4k viii PREFAC 8H it into the form, in which it appears in that book. Ir very rarely happens, that a@ new method of cure in any difeafe gives univerfal fatisfattion : however, not only Dr. Freind and my/elf inva- riably perfifted in this from the firft time I mentioned it to him 5 but fe- veral phyficians likewife, both in town and country, to whom we im- parted it, found its falutary effects. But there never are wanting fome men of fo invidious a turn of mind, that their principal pleafure confifts in blackening the reputation, and decry- ing the produétions of others; as if what they firip their neighbours of, was to be added to their own cha- ratters. Thus Dr. Freind’s book had no fooner appeared in public, but Jome of this flamp flew to arms, as if ta fave the common-wealth. In front of this band ftood forth Dr. John Wood- 3 ward, Pes &. Fs AoClk: ix ward, phyfic-profeffor at Grefham- College, a man equally ill-bred, vain, and ill-natured, who, after being for some time apprentice to a linen-dra- per, took it into his head to makea colleétion of fhells and foffils, in or- der to pafs upon the world for a phi- lofopher; thence having got admiffion into a phyfician's family, at length, by dint of intereft, obtained a Doétor’s degree. This man publifbed a book, intitled, ‘The ftate of phyfic and difeafes (1), wherein he took great h- berties with Dr.Friend, and thofe in the fame fentiment with him, but point- ed bis arrows moft particularly at me; and thefe were neither arguments nor experiments, of which he had none, but bare-faced calumny and raillery, which he poured forth in abundance. "Tis much againft my will, that I thus revive the remembrance of that libel, which already is well nigh funk in- (1) London, 1718. 8vo, to x PREFACE. to oblivion; and for which the author has been juftly expofed by Dr.Friend: nor foould Ihave wafted paper on this infignificant flory, had not the arro- gance and vanity of the man extorted it from me. And in fine, if I have dwelt longer on this whole affair than might be expected, my motives were, firft, to explain who was the author of this method of practice, and then, how little foundation Dr. Woodward had for bis perfonal reflettions and brawling. _ Now, as to what concerns this Difcourfe, I muft inform the public, that I have preferred perfpicuity to flowers of language, by delivering every precept in as few words as to me feemed confiftent with a clear conveyance of my notions: and I have added fome particular rules and cautions relating to cathartics, for the fake of young phyficians chiefly ; who are aften difpofed too rafbly 3 to PREF ACE, x1 to attempt, and too eagerly to em- brace every novelty in prattice, efpe- cially, when handed down to them from perfons, of whom they have a high opi- nion. For nothing can be fo uniwverfal- ly ufeful, as not to be liable. to fome exception; and it is fometimes as great a mark of found judgment, not to do mifchief, as to do good (1). Where- fore, not only in this cafe, but in all others within the compa/s of our art, the phyfician ought conftantly to rea member that of the poet (2), Nothing does good, but what may alfo hurt, Wuen I had finifbed this {mall work, I thought it might be no lefs agreeable than ufeful to the gentlemen of the faculty, if to it I annexed Rha- zes’s treatife of the Small-Pox and Mealles, faithfully tranflated from the (1) Hippocratesinhis | (2) Ovid.Trif?.Lib.ii, firft book of Epidemics. | ver. 266. B2 original Xi PREFACE. original Arabic into Latin: as it con- tains an ample detail of many things relating to the nature and cure of thefe difeafes, which, making proper allow- ances for time and place, coincide pretty much with the dotirines I have laid down. And indeed, it has given me no {mall pleafure, to fee my fenti- ments confirmed by the greateft phyfi- cian of the age be livedin. But I have often wondered how it came to pafs, that this book had never before been ublifbed either in Arabic, or in Latin from the Arabic. RobertStephens was the firft who publifbed it in Greek, at the end of his edition.of Alexander Trallian’s Work in the year 1548 (1). The Greek copy has been tranflated into Latin by three feveral perfons ; the firft of whom was Georgius Valla of Placentia, whofe verfion was pub- (1) The Greek title is, ‘Pain Aoy@e wept AOHLIKS « i lifhed Paw EE PA GB. Xxilk lifbed at Venice, A. D. 1498. and went through feveral editions. This was followed by a fecond, done by Johannes Guinterius of Andernac, printed at Strafbourg in 1549: and Nicolaus Macchellus, a phyfician of Modena, put forth a third, printed at Venice im 1555, and again, in 1586(1). Mow the Greck copy was not tranflated direttly from the Ara- bic, but from a Syriac verfion, which latter feems to have been done for the ufe of the common people ; and upon comparing the Greek with this Latin tranflation from the Arabic, which I now publifh, it will appear very inaccurate, by the entire omiffion of fome things, and faulty rendering of others; whether through the infuff- ciency, or negligence of the Syriac or Greek tranflator, I fhall not deter~ (1) Vid Fabricii Biblioth. grec. vol, xii. p.692. Mune, xiv FRE F -A-C:E: gine. But the manner how I acquir= ed my copy is this. AFTER having caufed a diligent Search to be made in our public libra- vies for an Arabic copy of this trea- tife to no purpofe, I wrote to my good friend, the celebrated Dr-Boerhaave, profeffor of phyfic in the Univerfity of Leyden, intreating him to inform me, if fuch an one could be found in the public library there, which I knew to be very rich in Arabic manufcripts. A copy was accordingly found, which he got tranfcribed by the Arabic pro- feffor, and kindly fent it over to me ; but it proved to be full of faults. This, however, I gave at two feparate times to two gentlemen of character, to put it into Latin. One was Solomon Negri, @ native of Damafcus, ex- tremely well verfed in all the Orien- tal tongues; the other John Gagnier, Arabic PREFACE. XV Arabic reader at Oxford: and they both performed the tafk with great diligence. But upon comparing the two verfions, I obferved that they dif- fered in feveral places, not in the dic- tion only, but even in the fenfe: where- fore, as I have no knowledge of the Arabic zongue, I could not determine which of the two to prefer. This incertainty made me apply to my worthy friend, the rev. Dr. Thomas Hunt, for feveral years paft Arabic profeffor in the Univerfity of Ox- ford, and lately made Hebrew pro- feffor likewife, who, among his many eminent qualities, is univer, ally ef- teemed a great mafter of the Eaftern languages. This gentleman, at my requeft, gencroufly undertook the pro- vince of ftrittly collating the two Latin verfions above-mentioned with the Arabic copy, im my prefence ; and out of them he compiled this, ae f which XVi TRE A CH. which I now give to the public ; and doubtlef; he would have made it much better, had the Arabic copy been more correct. London, Sept. 29>. 1747» > DPISCOURSE SMALLPOX MEASLES. CHAP. 1. Of the origin of the /mall pox. EFORE I enter on the me- dical part of my fubjed, I fhall briefly enquire into. the ori- gin of the fmall pox, and the man- ner of its propagation from thofe countries where it firft appeared, almoft over the whole face of the earth, as far as I can trace it in hiftory : for thefe points once fettled GC W ill 2 Of the origin will throw a confiderable light on the nature of the ciftemper, and the methods of cure, wiiich I fhall pro- pofe in the fequel of the Di/cour/e. Tua rT this is a modern difeafe, whereby I mean, that it was not known to the antient Greek and Roman phyficians, is to me a mat- ter beyond all doubt. For I think they are widely miftaken, who ens deavour to prove, that the anthrax, epinyétis, and fuch like eruptions on the fkin, were our /mall pox : becaufe it is more than probable, that the ancient phyficians, who were extremely diligent in. the: de- {cription and diftin@ive charaéteri- {tics of all difeafes, would not have been content with barely mention- ing this, which is fo contagious, and makes fuch dreadful havock among mankind; but would have minute- ly defcribed it, had they been ac- quainted with it. WHERE- of the fmall pox. 3 Wuererore we muft have re- courfe to the writings of the 4ra- bian phyficians for the firft notices of this difeafe. The chief of thefe was Rhazes, who lived about the year of Chrift pcccc. We havea large volume of this great man, publifh- ed under the title of his Cozzinenr, a treafure of phyfic, which feems to have been compiled from his com- mon-place book. In this he informs us, that a phyfician, whofe name was Aaron (who wrote thirty books of phyfic) had treated of the dia- gnoftics, the various kinds, and the method of cure of the fmall-pox(r). Now this 4aron was born at Alexan- dria, and in the reign of Mohammed practifed about the year pcxx11 (2). Whence the learned Dr. Freind con- jectured, that pofibly the /mall-pox took its rife in Egypt (3). But the ori- bift. Dynaft. 2. 99. (3) Oper. p. 330. 2 gin (1) Contin. 419. 2. (2) Vid. Abulpharajii 4. Of the origin gin of the difeafe is carried farther back than the time of this Aaron, by Dr. ‘Fohn ames Reifke, who fays that he read the following words in an old Arabic manufcript of the public library at Leyden: This year in fine, the Jmall-pox and meafles made their firft appearance in Ara- bia(t). By this year he means that of the birth of Mohammed, which was the year of Chri? pixx. Now upon mature confideration of the whole affair, I am inclined to think that there are certain dif- eafes, which are originally engen- dered and propagated in certain countries, as in their native foil. Thefe by Hippocrates are called difeafes of the country(2); and fome of them, fprung up in various parts of Europe and Afia, from peculiar (1) Hocdemum anno | inaug. Lug. Bat. 1746. comparuerunt primum | (2) Neoquala emyu- in terris Arabum vari- olae et morbili. Dip. Pie defects of the fmall pox. 5 defeéts in the air, foil and waters, he has moft accurately defcribed (1): but the more modern Greeks call them endemic difeafes (2 ). Thefe, in my opinion, always pee in their refpective native places, as proceed- ing from the fame natural caufes perpetually exerting themfelves. I r is found by experience, that fome of thefe are contagious, and that the contagion is frequently propagated to very remote coun- tries by means fuitable to the nature of this or that difeafe. For fome not only communicate the infection by immediate contaé& of the found with the morbid body, but have fuch force, that they {pread their pernicious feeds by emitting very fubtile particles; which lighting on foft fpongy fubftances, fack ag cote ton, wool, raw-filk, and cloathing, (1) Lib. de aére, aquis, | (1) Evdiyates. Vid.Galen, ef locis. Com.i. in Epidem. Hip. pene- ee Of the origin penetrate into them, and there re- main pent up for a confiderable time: in the fame manner as I have elfewhere accounted for the wide progrefs of the plague from Africa its original country (1). Others, on the contrary, are infectious by con- tact alone. Wherefore the firft fort may be fpread by commerce, but the jatter by cohabitation only. O ¥ this kind is the venereal dif- eafe ; which, according to hiftorians of the moft undoubted credit, is a native of fome of the American iflands, efpecially Ali/paniola, and was brought over into Spaim near the end of the fifteenth century: thence, in the year mccccxev, it was carried to/Vaples, during the war between Ferdinand ot Aragon and the French, by fome Spanifh troops, who had contracted it in the afore- (1) Difcourfe on the plague, Parti. chap. 1. page 21. edit. 1744. faid of the {mall pox. y | faid ifland. For thefe and the French foldiers having at different times had communication with the fame women, according as the fame towns alternately fell into the hands of the two contending parties ; this filthy difeafe firft fpread itfelf over the two armies, thence made its way into Italy, and has fince infe&ed moft parts of the habitable world (1.) Anp I very well remember, that a certain Exgli/b merchant, who had refided many years in Mofcovy, af- fured me, that the venereal difeafe was hardly known in that country before the reign of the late Czar Peter the Great: becaufe till that time the traffick carried on by the Mofcovites did not require much communication or dealing with fo- reigners. But after that emperor had taken the refolution of vifiting (r) Vid. Afruc de morbis venereis, Lib. i. cap. 10, II. other 8 Of the origin other parts of Europe, and had fent many of his fubjeéts abroad to learn trades and manufactures ;_ thefe car- ried back with them the dire effects of their unlawful luft into their na- tive country ; which raged there with the greater feverity, as inflamma- tions and ulcers are the-more difh- cult to be cured in cold climates. Bur to return to the {mall pox. I really take this difeafe to be a plague of its own kind, which was originally bred in 4frica, and more efpecially in Ezhiopia, as the heat is exceflive there ; and thence, like the true plague, was brought into 4ra-\ bia and Egypt after the manner above-mentioned. Now if any one fhould wonder why this contagion was fo long confined to its native foil, without {preading into diftant countries ; I pray him to confider, that foreign commerce of the finall pox. 9 commerce was much more fparing- ly carried on in ancient times, than in our days, efpecially between mediterranean nations: and like- wife, that the ancients feldom or never undertook long voyages b fea, as we do. And Ludolfus ob- ferves, that the Erhiopians in parti- cular were ignorant of mercantile affairs (1). Therefore, when in pro- cefs of time the mutual intercourfe of different nations became more frequent by wars, trade, and other caufes ; this contagious difeafe was {fpread far and wide. But towards the end of the eleventh century, and in the beginning of the twelfth, it gained vaft ground, by means of the wars waged by a confederacy of the Chriftian powers againft the Siz- racens, for the recovery of the Holy land; this being the only vifible recompence of their religious expe- (1) Hitt, Aethiop. Lib. iv, cap. vii. D ditions, 10 Of the origin ditions, which they brought back to their refpective countries. From that time forward, wherefoever this moft infectious diftemper once got a footing, there it has obftinately held uninterrupted poffeflion. For the purulent matter, which runs out of the puftules, being caught in the bed-cloaths and wearing apparel of the fick, and there drying, and re- maining invifible, becomes a nur- fery of the difeafe, which foon breaks forth on thofe, who happen to come in contact with it; efpe- cially, if the feafon of the year, and {tate of the air be favourable to its action. I wn ‘this place, it may not be im- proper, in confirmation of the fore- going doétrine, to relate the follow- ing fact, which was attefted to me by a gentleman of great experience, who had been for many years go- vernor of the fmall pox. 1I vernor of Fort Sz. George in the Eaft-Indies. | While he was in that poft, a Dutch fhip put into the Cape of Good Hope, fome of the crew of which had had the fmall pox in the voyage thither. The na- tives of that country, who are called HAfottentots, are fo wild and ftupid, that they might feem to be of a middle {pecies between men and brutes ; and it is their cuftom to do all fervile offices for the failors, who land there. Now it happened, that fome of thefe miferable wretches were employed in wafhing the linen and cloaths of thofe men who had had the diftemper: whereupon, they were feized with it, and it raged among them with fuch violence, that moft of them perifhed under it. But as foon as fatal experience had convinced this ignorant people, that the difeafe was fpread by conta- gion, it appeared, that they had na- D 2 tural 12 Of the origin, &c. tural fagacity enough to defend themfelves. For they contrived to draw lines round the infected part of their country, which were fo ftrictly guarded, that, if any perfon attempted to break through them, in order to fly from the infection, he wasimmediately fhot dead. Now this fa& feems the more remarkable, as it evinces, that neceflity compel- led a people of the moft grofs igno- rance and {tupidity to take the fame meafure, which a chain of reafoning led us formerly to propofe, in order to ftop the progrefs of the plague(r); and which, fome time after, had a happy effect, not only in checking, but even entirely extinguifhing that dreadful calamity in France, where it broke forth, and threatened the reft of Europe with deftruction. (1) Difcourfe on the plague, Part ii. chap. 2. page 109. CH AP; Of the nature, &e. 13 MMIII GHA Poo Of the nature and forts of the Small pox. AVING fufhiciently proved in i the preceding chapter, that the {mall pox isa difeafe of tke pe- ftilential tribe; in order to a clearer knowledge of its. nature, I will briefly premife my notions of pe- ftilence. Aut fevers, which attack the whole body, may be conveniently ranged under the three general heads of fimple, putrid, and pefti- lential. SimPxe fevers arife froma long- continued excefs of velocity in the motion of the blood, and its con- fequences, a difturbance of it: due, 3 mixture, ug Of the nature and forts mixture, and. an interruption of the fecretion of the humors in the fe- veral parts of the body. Purrip fevers are caufed, when, together with a concurrence of thefe circumftances, a lentor enfues in the capillary blood-veffels; and as this fizy blood is gradually pufhed for- ward by the force of the circulation into the veins, it there becomes pu trid, and impregnates the reft of the mafs witha malignant quality, which is communicated both to the inter- nal and external parts of the body. PEStTILENTIAL fevers, in fine, I call all thofe, which are accompanied with fome fort of poifon. Now, of whatever nature this happen to be, it not only infects and corrupts the blood, but more particularly: feizes on the fubtile nervous liquor, which is. called the animal {pirits. Hence it is, that thefe fevers.act with greatet rapidity of the fmall pox. 15 rapidity and violence, and are much more fatal than the other forts. “But this one circumftance is common to all fevers, that nature endeavours to conquer the difeafe, by raifing fome ftrugele or other, in order to throw forth from the body whatever is prejudicial to life. Now, whereas the word Wature is made ufe of by phyficians in the eure of all difeafes, I will here, once for all, plainly declare my fen- timents of what we ought to un- derftand by that word. That there is fomething within us, which per- ceives, thinks, and reafons, is ma- nifeft beyond contradi@tion; and yet the nature of that Something can- not be fully and pertectly compre- hended in this life. Wherefore I fhall refign the difquifition of this point to thofe, who, while they know too little of, and care lefs for things falling under their fenfes, take great pleafure 16 Of the nature and forts pleafure in inveftigating thofe things, which human reafon is incapable of conceiving. However, thus far the foundeft philofophers agree concern- ing it, that it is fomewhat incorpo- real. For how can fluggifh matter, which is of itfelf void of all mo- tion, be the fource and firft caufe of thought, the moft excellent of all motions? Wherefore, it is fuffi- ciently evident, that this firft mover within us is a {pirit of fome kind or other, intirely different and fepa- rable from terreftrial matter, and yet moft intimately united with our body. Moreover, to me it feems pro- bable, that this active principle is not of the fame fort-in all; that the almighty creator has endowed man with one fort, and brutes with another: that the former fo far par- takes of a divine nature, as to be able of the [mall pox. 17 able to exift and think after its {e- paration from the body ; but that the latter is of fuch an inferior or- der, as to perifh with the body. The former was by fome of the an- cients called animus, the latter ayj- mma(x); and they believed, that they were both ingendered in our fpe- cies: but this I take to be an erro- neous pofition. For as their anima fuffices for the funétions of life in brutes, fo our animus ftands not in need of fuch an affiftant. Now this matter, if lam not miftaken, ftands thus: fuch is the compofition of our fabrick, that, when any thing pernicious has got footing within the body, the governing mind gives fuch an impulfe to thofe inftruments of motion, the animal {pirits, as to (1) Fur. Sat. xv. 148. ] animum quogue, Mundi Vide etiam Davifi Principio indulfit com-\ Not. ad Ciceron. Tujc. mums conditor ils | difput. Lib. 1. cap. 10. Tantum animam, nodis | E raife 18 «Of the nature and forts raife thofe commotions in the blood and humors, which may relieve the whole frame from the danger in which it-is involved. And this is done in fo fudden a manner, that it fhould feem to be the effe& of inftin@, rather than voluntary mo- tion ; though it be effected in us at the command of the animus, and in brutes by the power of the ani- ma. And indeed, thofe very mo- tions, which are commonly called natural and vital, as thofe of the heart, lungs, and inteftines, which perfevere through the whole courfe of life, even when the will cannot be concerned in them ; as they have their beginning from the mind, fo they are perpetually under its direc- tion. I could eafily bring many ar- guments in confirmation of thefe fentiments, but they would be fu- perfluous in this place. Befides that I am happily anticipated by the learned of the {mall pox. 19 learned and ingenious Dr. Porter- field, fellow of the royal college of phyficians at Edinburgh, who in a curious Differtation publifhed fome years fince (1), has treated this fub- ject with fuch perfpicuity, that there can be no room left for doubt. Bur from philofophy I return to medicine. Our fagacious Sydenham was fo far of this opinion, as to af- fert, that a difeafe is nothing elfe but an effort of nature to throw off the morbific matter, for the health of the patient (2). And Hippocrates, in his ufual manner, laconically expreffed the fame thing thus: JVarwure is the curer of difeafes(3). Now this I have obferved more particularly in pefti- lential fevers, in which the violence (1) Vid. MedicalEffays | dic. circa morborum publifo-d at Edinburgh, | acutorum hiftoriam, at Vol. iti. Effay xii. and | the beginning. Vol iv. Effay xiv. | (3) Néowv Pdores inrgots (2) Obfervation, me- | Epidem. Lib. vi, E 2 of 20 Of the nature and forts of the diftemper breaks forth on the fkin in the form of puftules, carbun- cles, and buboes ; all which are the very venom of the difeafe, as the common experiment of giving the {mall pox by inoculation plainly demonftrates. Thus having made it appear, that the {mall pox is an envenomed fever, I come to explain its different forts; for as to its hi- ftory, I refer to Dr. Sydenham, who was the firft that divided its whole courfe into certain flages, and gave the method of cure in each. Most authors divide the /mall pox into the diftinét and confluent forts, and eftimate both forts by the fize, number, and manner of eru- ption of the puftules. But in the prognoftic, they make fo wide a difference between them, that they pronounce the former fort to be al- moft void of all danger, but the latter of the {mall pox. 24 latter always dreadful in its confe- quences. ‘Thus much indeed is moft certain, that the confluent fort are, generally {peaking, much worfe than the diffiné?, and that many more die of thofe than of thefe. But yet it fometimes happens, that a difiné&# Jort may prove more dangerous than the common confluent jort. More- over, there are many fymptoms ex- tremely dangerous, which are pe- culiar to the di/tin& kind, as I thall fhew anon. For the danger does not fo much arife from the quan- tity of the purulent matter, as from other circumftances, which fhall be explained in their due place. Wuererors, in my opinion, the Jmall pox may more accurately, and agreeably to the nature of the dif eafe, be divided into fimple and ma- lignant, | TI CALL « om ©6Of the nature and forts I cat fomple all that fort, in which the eruption is attended with a flight fever of fhort duration, the puftules fill kindly, make good mat- ter in a few days, and in fine, fall off in, dry {cabs. Tus malignant {ort is that, in which the eruption appears with a malignant fever, the puftules hard- ly come to any tolerable degree of maturity, and either fuppurate not at all, or if they do in fome mea- fure, as the fever is never off, it is with great trouble that they at length end in little crufts. Tat malignity appears in fuch various forms, according to the dif- ferent nature of the puftules, that its characteriftic figns have given va- rious appellations to the fmall pox: whereof the chief differences, which have fallen under my obfervation, are thefe that follow. For the puftules are of the {mall pox. 23 are either cry/talline, warty, or bloody. I am well aware, that authors have run into a greater number of fub- divifions; but I look on the reft to be either a combination of fome or all of thefe, or only different de- grees of the fame kind: a thing which frequently happens in an ir- regular difeafe. I carz thofe puftules cry/aliine, which, inftead of thick, well-digeft- ed matter, contain nothing but a thin, pale water, and are in fome meafure pellucid. And this fort is fometimes obferved, not only in the confluent, but alfo in the diffind {mall pox. Tey are called warty, when the puftules contain no fluid, but grow hard and prominent above the {kin in the manner of warts, Thefe are peculiar to the di/tinG fort. 24 Of the nature and forts Tu bloody puftules are pro- duced more ways than one. For I have feen cafes, where, at the very beginning of the difeafe, the puftules were fo many {mall tubercles full of blackifh blood, refembling thofe raifed on the fkin, when pinched with a forceps. And thefe were fol- lowed by an intermixture of purple and livid f{pots, fuch as phyficians defcribe in the true plague. But it more frequently happens, that pu- ftules coming out very thick, on the third or fourth day after, when they ought to fill, become livid, and a little bloody, with black {pots fpread over the whole body; which forebode death in a day or two, be- caufe they are real gangrenes. It very often falls out at this time, that a thin blood flows not only out of’ the patient's mouth, nofe, and eyes, but alfo by every outlet of the bedy; but more efpecially by the of the mall pox. 25 the urinary paflages, through which it likewife iffues fometimes on the firft days of the diftemper. Thefe are manifeftly of the confluent fort. To thefe Dr. Freind (1) has added a fourth kind of {mall pox, which he calls /liguofe, in which the pu- ftules refemble little round, foft, hollow bladders, and contain no fluid. But this I place among the cryftalline fort, the only difference betweeri them being, that in this cafe one part of the fluid, which had been thrown into the puftules, flies off through the fkin, and the other is abforbed by the lymphatics back into the body. Ir is always a difficult tafk, and fometimes a needlefs one, to inve- {tigate the true caufes of things. But as the public may perhaps ex- pect, that I fhould account for the (1) Epift. De quibufdam variolarum generibus. above- 26 Of the nature and Sorts above-mentioned differences in this difeafe ; I fhall fay, that the prin- cipal reafons of thefe differences, which have occurred to me upon mature confideration, are, the al- moft infinite variety of tempera- ments 1n various individuals; the Jeafons of the year and their changes, and in fine, many accidents which befal the body, between the time of catching the infe@ion and the ap- pearance of the difeafe. For ino- culation fhews, that the fmall pox does not break forth before the eighth or ninth day from receiving the infection. Possisty it may be thought ftrange, that, in enumerating thefe caufes, I have not mentioned a word of the nature of the infecting par- ticles. But, befides that the know- ledge’of this is not attainable by us, it feems to have no great influence on of the Jmall pox. 27 on the production of this or that particular fort of the diftemper. For we frequently obferve, in the fame family, where one perfon catches it from another, that fome have a fa- vourable, and others a bad fort, Bu r fuch is the power of sempe- raments of body, that they defcend to thofe of the fame blood by a fort of hereditary right: whence fome difeafes are found to be familiar and fatal to certain families. As tothe /ea/ons of the year, we find, by daily experience, that fome of them are fitter to produce cer- tain difeafes than others ; that they are the caufes of epidemic fevers ; and that thofe chiefly, in which fome fluid is to be thrown off by the fkin, are the moft remark- ably liable to be affected by their changes. F 2 Burt 28 Of the nature and forts But numberlefs are the thin comprehended in the third article, to wit, all thofe accidents, which happen to the body from the time of taking the infection to the erup- tion of the puftules. For the poifon is far from lying quiet all this while, but is conftantly and gradually ex- erting its malignity, by firft cor- rupting the animal {pirits, and then the whole mafs of blood and hu- mors. Wherefore, if bodily exercife, diet, or the affections of the mind (which have great power in this cafe) fhould happen to make any particu= Jar alteration in the fermenting flu- ids, they may eafily occafion vari- ous forts of puftules, poflibly in the manner I am going to explain. Tue /mple {mall pox are fuppu- rations made, while the blood is not fo far vitiated, but that the deriva- tions of the fmall pox. 29 tions of the humors into the pro- per parts may be effected tolerably well, and the natural fun@ions are not entirely hurt. But in the mg- lignant {fort the cafe is quite differ- ent. For the whole mafs of humors is corrupted more or lefs, according to the nature of the difeafe ; and the blood is in fuch confufion, that the purulent matter cannot be thrown upon the {kin. Now, in this cafe, fometimes a thin fluid is thrown. out, which, when watery, makes cry/alline puftules; when thick and vifcid, warty; and filiquofe, in fine, when the fluid has been te- forbed by the lymphatics into the blood, and has left the puftules quite empty. Befides, the texture of the blood is too frequently broken to that degree, that it is obftructed, and flagnates in the fmall veffels- whereupon, the fkin is ftrewed with black go ©6Css«Of the nature and forts black fpots, which are fo many real gangrenes, and hemorrhages enfue thro’ all the outlets of the body ; whence this is called the bloody fort. That thefe horrid fymp- toms are the effe@s of an acrid poifon, appears plainly ; becaufe the fame happen to thofe, who have been bit by the Hemorrbhois, a Lybian ferpent, according to Lucan’s beau~ tiful defcription : A fierce Hemorrhois ruck both his fangs Deep into Tullus; 2 brave valiant youth, And fond admirer of great Cato's worth, And as Corycian faffron, when "tis /queez'd, Pours forth its yellow juice thro’ all the holes Of the bard preffing boards; fo from the pores Of all the parts flow'd ruddy venom'd gore. His tears were bloody; nature's paffages, For their own humors, were all fill'd with blood. His wae his nofe, choak’d up with filthy clots : Red of the fmall pox. 31 Red fweats tranfpir'd from all the fkin in- amd. Eis body feem'd one univerfal wound (1). But from thefe objeéts of terror, it is time to pafs to thofe which may afford comfort. (1) Lib, ix. ver. 806. CHAP. Of the methods of cure SOA MORSE IE ROR ORO ah Ram Cah Rea? Rea it Reet” Loam Cee C A487 Aa. Of the methods of cure in the Jmall poi. | T is moft evident, that all pe- i ftilential difeafes are accompa- ii nied with the higheft inflamma- tion of the blood and humors, and therefore they all require emptying and cooling. I begin with the /fm- ple {mall pox, and fhall afterwards defcend to the treatment of the sza- lignant {ort in its feveral varieties. Bur in this place it feems pros | per to clear up two material points. ei The one regards the management t of the fick, and the other, the diet f proper for him. Wiru refpeé to the firft, ferious attention: fhould be given both to the in the {mall pox. 33 the feafon of the year, and to the ftrength of the patient. For the fame things, that are done with fafety in fummer, may be attended with dan- ger in winter; and young lads or robuft men eafily bear what might deftroy infants, or weakly women. But let this be a general rule, to keep the patient in bed during the firft days of the diftemper, taking care to defend him from the incle- mency of the winter by proper means, and to moderate the excef- five heat in fummer by cool air. But to chill, and as it were to freeze up the fick in winter, is not the part of a prudent phyfician, but that of : a fool-hardy empiric, trying expe- riments at the expence of unhappy people’s lives. Wherefore a mean is to be obferved herein, by manag- ing the patient, in fuch a manner, as neither to ftifle him with heat or eloaths, nor check the eruption and G per{pi- 34 Of the merhods of cure perfpiration by cold. However, great care ought to be taken in general, to fupply him with pure and cool air, which he may take in plenti- fully: becaufe a hot air caufes dif- ficulty of breathing, checks the fe- cretion of urine, and increafes the number of puftules on the inter- nal otgans of the body; the confe- uences whereof we may juftly: ap- rehend to be inflammations, and, towards the end of the difeafe, gan- orenies. Niru regard to diet, it ought to be very flender, moiftening, and cooling ; fuch as oatmeal or barley- gruel, &c. Neverthelefs, as the food is to be adapted to the feveral ftages of the difeafe, the beft regimen in the beginning is that, which will keep the body open, and promote urine. Thefe advantages. are ob- tained by boiling preferved fruits with in the (mall pox. 35 with their food, efpecially figs, da- mafcene plumbs,and tamarinds, and giving them fubacid liquors for drink ; as fmall-beer acidulated with orange or lemon juice; whey turned with apples boiled in the milk, or with wine; emulfions made with bar- ley-water and almonds; Mofelle or Rhenifh wine plentifully diluted with water; or any other things of this kind. W uen this fort of diet did not keep the body open, the Arabian phyficians added manna to it; but this they did fparingly, and with caution. For it is guite neceffary, fays Avicen, that the body be open in the beginning (1). Which is one of the moft important advices, that can be given in this difeafe, if to it be add- ed, that urine muft be made plen- (1) De variolis et mortillis, G 2 tifully. 36 Of the methods of cure tifully. For there is a wonderful correfpondence between the fkin and the kidneys; whereby, whatever fluid is wont to be fecreted by the cuti- cular glands, may with great eafe be evacuated by the urinary paflages. Wherefore it is very proper to draw off as much of the matter of the dif- eafe as can be done, by thefe paf- {ages ; in order to prevent the over- loading of the internal parts. Now let us pafs on to medicines, and, in the firft place, d/cod-letting is neceffary. But as diffentions fre- quently arife on this fubjeét, fome rules are to be laid down concern: ing it. Ir is agreed on all hands, that this remedy is not very fuitable to the tendereft age. But yet, as the blood of infants is generally too thick, and too much in quantity for the bulk of the body ; and as they ‘in the {mall pox. 37 they are oft-times feized with con- vulfions, upon the appearance of the difeafe, fome evacuation ought to be made: which may be fafely effected by leeches applied to the temples, or behind the ears. Like- wife, if blood cannot be drawn from the arm, in moft young fubjects ei- ther of ie jugulars may be opened without inconvenience. Tuar regard is to be had to the patient’s ftrength of what age f{o- ever, is manifeft to all. But the weaknefs is feldom fo great, as not to bear fome lofs of blood, unlefs it be after fome extraordinary eva- cuations. Nor is the pulfe to be over-much depended on in this cafe: for it often happens, that the thick- nefs of the blood prevents the {e- cretion of the ufual quantity of ani- mal fpirits in the brain, and that the vital fluid is not propelled from the heart 38 Of the methods of cure heart with due force: in which cafe, by removing the oppreflion, the pa- tient’s ftrength is obferved even to increafe with the bleeding. But in what proportion blood is to be taken away, will be beft determined by the vehemence of the difeafe. Many of our phyfici- ans imagine that they have done their duty, when they have order- ed one bleeding, and are vaftly cau- tious of opening a vein at all, after the firft appearance of the puftules ; for fear of checking the eruption. But this is certainly an ill-timed cau- tion: for in youths and adults it is often neceflary to draw blood two or three times, only with an intermiffion of two or three days between each time. And indeed blood-letting is fo far from being an obftacle to the eru- ption of the puftules, if the patient be not too weak, that it forwards it confiderably; and for the very fame reafon, in the {mall pox. 29 reafon, that, in large abfceffes, when there is too great a fullnefs, and the heat too intenfe, the fuppuration is brought on quicker and better by taking away fome blood. I wave often obferved, when in the beginning a vaft number of {mall puftules foreboded a difeafe of the worlt kind, that the face of affairs was fo remarkably changed upon one or two bleedings, that the pu- ftules increafed in fize, and dimi- nifhed in number (the greatnefs of the difeafe thus giving way to the sreatnefs of the remedy) by which means nature acquired fufficient ftrength to expel the noxious hu- mor. For it is moft certainly true, that nature labors at the expulfion of the poifon in the moft perfect manner, that is, endeavours to make the puftules fill up as much as pof- fible; and for that end fhe requires every 4.0 Of the methods of cure every thing to be quiet within the body, and always abhors confufion. And indeed, the reafon why the con- fluent {mall pox is worfe than the diftin& fort is not, becaufe the mat- ter of the difeafe is more abundant in the former than in the latter, but becaufe it is not pufhed out in a proper manner. For upon a ftrict examination we generally find, that the greater quantity is difcharged in the d:/finé# {ort. New to conclude this head, fuch is the benefit of large and reiter- ated bleeding, that it is obferved to prevent thofe evils, which often attend the difeafe;, as a delirium, convulfions, difficulty of breathing, and the like. For the diffection of dead bodies fhews, that the infeétion is not confined to the external parts of the body, but {feizes on the in- ternal parts alfo. For I myfelf have feen in the {mall pox. 41 feen fubjeéts, in which the lungs, brain, liver, and inteftines were thick befet with puftules. Nor have I the leaft doubt, but that thofe fudden deaths, which fometimes happen to- wards the end of the difeafe, when there feemed to be no room left for fear, are occafioned by the efflux of the purulent matter from the burfted puftules on one or other of the nobler parts. Wherefore, no fe- ver is attended with more uncer- tain figns, on which to ground a fure prognoftic, than this, of which we are treating. Upon the whole, there is no time of the difeafe, where- in it may not be neceflary to draw blood ; if the violence of the fever require it, and the patient appear able to bear it. For it is always bet- ter to try a doubtful remedy than none. H A pbren- 42 Of the methods of cure A phrenzy, coming on the fourth day of the eruption, is juftly ef- teemed of very bad omen; _info- much that Dr. Freind fays, that be never faw a patient recover, who had had this /ymptom(t). But I can pofitively declare, that I have had better fortune; having reco- vered many, who had been feized with a delirium at that time, by drawing blood immediately, and then throwing in a clyfter. Arrer taking away as much blood as is requifite, it 1s proper to purge the body; which may be done with fafety enough, any time before the eruption of the puftules, But the purge muft be of the gen- tle kind; fuch as the infufion of fena with manna, or manna alone, efpecially for children, For no di- fturbance is to be raifed in the body. (1) Epift. de quibufdam variolarum gevseribus. But in the fall pox: 43 But firft a vomit fhould be given, if there happens to be any collec- tion of phlegm or bile in the fto- mach, or the ftomach to be loaded with food unfeafonably taken. As foon as it is certain, that the eruption is near at hand, moft phy- ficians are of opinion, that it ought to be promoted by all means. Yet we are to remember, that this is the proper work of nature ; and there- fore great care fhould be taken, nei- ther to increafe the motion of the blood over-much, nor fuffer it to grow languid. Ir was a wife faying of A/clepia- des, that he made ufe of the fever for its own cure(1): whereby he meant, that the fever is to be regulated in fuch a manner, that itfelf may throw off whatever is noxious to the body. (1) Celf. Lib. iii. cap. iv. H 2 Where- 44 Of the methods of cure Wherefore the true intention in this cafe is, to-keep the inflammation of the blood within due bounds, and at the fame time, to affift the expulfion of the morbific matter through the fkin. For both which purpofes a medicine, which I have experienced to be ufeful, is a pow- der compofed of two parts of the bexoardic powder, and one part of purified nitre; and fometimes of equal parts of both An adult may take half a drachm of this powder three or four times ina day, dimi- nifhing the quantity for children, in proportion to their age. And if the effervefcence of the blood run very high, a proper quantity of /pirit of vitriol may be added to the pati- ent’s drink. But if there be any keckings or reachings to vomit, they will be removed by draughts con- taining half an ounce of juice of lemons, in the [mall pox. 45 femons, with one fcruple of /alt of wormwood. Now, concerning thofe medi- cines which eafe pain, and pro- cure fleep, in this fevere difeafe ; thefe are not to be ufed over-hafti- ly : for all anodynes in fome mea- fure obftruct the feparation of the morbid humor from the blood, unlefs the pain happens to be ‘ex- ceflive: and moreover, if the vio- lence of the fever has raifed a de/i- rium, they generally make it worfe. Wherefore, it is not proper to em- ploy them, until the eruption of the puftules be compleated; but ‘after that, narcotics may be adminiftered with fafety. Thus it will be right to give the patient a dofe of tic thebaic tin€lure, or diacodion, every evening, efpecially if he be a youth or an adult perfon; for thefe me- dicines agree not fo well with in- fants. 46 Of the methods of cure fants. And fometimes, in cafes of very great inquietude, the dofe is to be repeated in the morning. For the fuppuration of the matter, ftag- nating in the puftules, is forwarded by quiet and fleep. But if, towards the end of the difeafe, the patient happens to be feized with a fhort- nefs of breath, or danger of choak- ing from vifcid flime, thefe medi- cines are to be intirely prohibited. In the mean time, if the patient is coftive, which is generally the cafe, and the fever continues; the body is to be opened with a clyfter every fecond or third day. Ir may be needlefs to obferve, that, if this method is proper in the diftin& {mall pox; it will be found more neceffary ftill in the con- fluent, which is attended with oreater fear and danger. Fron in the {mall pox. 47 From the fmple I now pafs to the malignant {mall pox, of which I have already eftablifhed three forts, to wit, the cryffalline, the warty, and the d/ody. N ow, this obfervation holds good in all kinds of the difeafe, that the more the puftules tend to fuppura- tion, the greater are the hopes of recovery; and therefore, when that does not go on according to our wifhes, all poflible means are to be employed to throw the morbific humor on the fkin ; with which in- tention every thing is to be done in this cafe, which we have propofed in treating of the fmp/le fort. But yet each fpecies of the malignant fort requires a peculiar confidera- tion. Wuereas, in the ery/ralline fort, the water of the puftules can never be brought to a laudable fuppura- tion ; 48 Of the method: of cure tion; it ought to be carried off by thofe’ paflages im the body, which are naturally adapted to the fecretion of the thinner fluids. Now I have faid above, that there is a great cor- refpondence between the fkin and the kidneys. Therefore, while the thinneft parts of this water are made to tranfpire through the fkin, the grofler parts ought to be drawn off through the urinary paflages, by diu- etic medicines. Of this tribe there is nothing better than witre, and that may be adminiftered three or four times a day, in fuch quantities as may not offend the ftomach, to wit, afcruple, or half a drachm, diffolved in {mall wine, which is the only fort that agrees with this difeafe, till to- wards the end; when it may be pro- per to allow the patient a little Ca- nary (Dr. Sydenham's favourite li- quor) or any other foft and generous wine to fupport his ftrength. But while in the [mall pox. 49 while zitre is thus taken, it will be right to interpofe thofe medicines, which cherifh the heart, and pro- mote the flux of the humor into the puftules : fuch as Raleigh’s cor- dial, or the cordial confeé&tion ; the bexoardic pouder, fometimes with a little /affron ; and the plain fpirit of hartfborn. Befides thefe, on the fifth or fixth day of the eruption, blifters are to be applied between the fhoulders, and to the arms and legs: for which purpofe, the difering epi- them is moft convenient, as its foft confiftence enables it to reach the fkin between the puftules, and ftick to it. For by this difcharge of the ferofities, the fever, which increa- fes, when there is no farther deri- vation of humors to the fkin, is fea- fonably prevented. I x now irdeed, that moft of our phyficians apply this remedy earlier, I and so 0 Of the methods of cure and even on the firft days of the difeafe, in every malignant {mall pox ; but there is juft reafon to fear, that the great commotion raifed in the blood by the acrimony of the flies might be an obftacle to the due propulfion of the humor into the beginning puftules, Tue warty {mall pox is more dangerous than the cry/falline ; be- caufe the matter of the difeafe, be- ing too thick, can neither fuppurate, nor pafs off by urine. Wherefore, it is neceflary to ufe the utmoft en- deavours to take off the fever, and to provoke {weat, in order to digeft the morbid humor, by the cordial medicines afore-mentioned. And blifers ought to be applied in this cafe likewife. But the 4rabian phy- ficians pronounced this fort of the difeafe to be always fatal (1). (1) See Rhazes's treatise annexed, Chap. viii. LasTLy, in the /mall pox. 5 Lastiy, that fort, which I have called the d/oody {mall pox, requires peculiar attention. Now in this fort, if there is any room for phyfic, thofe medicines bid faireft for fuccefs, which by their ftypticity thicken the blood in fome meafure, and fo check it, that it cannot break thro’ even the {malleft arteries. The beft of this kind arethe Peruvian bark, a- lum, and that /pirit which is called oil of vitriol. Now thefe are to be ufed alternately in this manner. A drachm of the dark may be given every fixth hour ; and, three hours after, a proper quantity of alum. It will be avery powerful medicine, if thus compounded. Melt three arts of alum on the fire, with one part of that infpiffated juice, which is improperly named dragan’s blood : when the mafs is grown cold, re- duce it to a powder ;.a fcruple of which, made into a da/us with com I 2 Jerve 52 Of the methods of cure Jerve of red rofes, will be -a proper dofe, The moft convenient man+ ner of giving the oi/ of vitriol, is in the sinéture of rofes; five or fix {poon- fuls whereof may be taken feveral times in the day. And befides, the patient’s common drink may be aci- dulated with it ; efpecially, if pur- ple or black {pots appear inter- {perfed among the puftules. And this medicine will be of great fer- vice, not only in the 4/sody, but in all the other forts likewife, ‘accom- panied with thefe {fpots. This one thing more I will add, that I have experienced the ufe of d//ers to be fafe enough in this cafe, when a de- rium requires their application. J have indeed feen fome patients re- cover by this method, who had dif- charged large quantities of blood by the urinary canal at the time of the eruption of the puftules ; but it is worthy of notice, that, in all thefe, the in the-fmall pox. 53 the difeafe terminated in fome con- fiderable evil. For they were. tor- tured, either with boils breaking out in many parts of the body, or with glandular fwellings under the ears or arm-pits, which were not eafily brought to fuppuration. I likewife remember the cafe of a young man, one of whofe tonfils was deftroyed by a gangrenous ulcer which was very troublefome to cure. Thus upon the whole it is manifeft, that ~ it is extremely difficult to clear the mafs of blood of this poifon; and that a perfect recovery is not to be procured without a fuppuration, ei- ther in its due courfe of time, or in the laft flage of the diftemper. Bur in every fort of this difeafe, jt is proper to open the body on the decline, that is, on the ninth or tenth day from the eruption; becaufe a putrid fever generally comes on about this 54 Of the methods of cure this time, while the puftules are dry- ing ; or upon the fubfidence of the {welling of the inflamed fkin, where there is no fuppuration; which fe- ver cannot be taken off with equal fafety by any other means. But gentle cathartics alone are to be em- ployed in this cafe, fuch as I have advifed before the. eruption of the puttules, Tuts whole affair I formerly ex- plained, and illuftrated with proper ex- amples, in my Letter to Dr.Freind(t); and that gentleman likewife, abun- dantly confirmed it afterwards, by the authorities of ancient and mo- dern phyficians. So that whofo- ever refufes his affent to this practice, mutt refolve not to fee at noon-day. All fevers have their certain. peri- ods; and where the poifonous mat- (1) Vid. Freind. Com- | ribus. Et Epift. de pur- mentar. Vii. ad Hippo- | gantibus in fecunda va- crat, de morbis popula- | riolarum febre adbibend. ter in the [mall pox. 55 ter has once infected the humors, the putrid fuel of the difeafe can hardly be thrown out of the body early enough. And indeed, when this rule is not obferved, we daily fee the diftemper followed imme- diately by a hectic fever, attended with a cough, {pitting of purulent matter, fhortnefs of breath, and other fymptoms of the lungs being affected. Bur I muft obferve in this place, that, however beneficial purging may be at this time ; yet, if the body happens to be too loofe, either from the natural ftate of the inteftines, of by. frequent clyfters, this remedy becomes lefs neceffary, or at leatt, may be poftponed for fome. days. For great regard is to be paid to the patient’s ftrength, which the length of the illnefs has more or lefs im- paired. More- 56 Of the methods of cure Morzover, it is requifite to be very circumfpect, whether there be any remains of the purulent matter lurking under the withered fkin of the puftules; for this is fometimes fo manifeftly the cafe, that tho’ the {cabs appear dry and hard; yet upon fome of them breaking here and there, there iflues forth very fe- tid matter. In this circumftance, the body is not to be purged, but rather to -be fupported by proper diet, until the matter is all come away ; which I have feen continue running to the twenty fourth day of the difeafe, and yet the patient re- covered. I fhall never forget the cafe of a certain young man of a very robuft conftitution, who had fo dreadful a fort of the confluent {mall pox, that when the puftules fhould have ripened, his whole face was become black and dry, and in fhort, thoroughly mortified. As the cafe in the [mall pox. 87 cafe feemed quite defperate, I or- dered incifions to be made to the quick in many places, and fomen- tations of a decoction of emollient and warm plants, with the addition of camphorated fpirit of wine, to be applied to the parts: whereupon there followed a difcharge of mat- ter from the incifions of fo offenfive a {mell, that none of the attendants could bear to ftay in the room; and having at the fame time promoted this difcharge by proper digeftives, and duly purged him, he at length recovered. But his mangled face bore the lafting marks of the malig- nity of the diftemper, and. of the goodnefs of the cure. In Fine, it will be of ufe at this time to take away fome blood, if the heat be too great, and the pa- tient have ftrength enough left to bear it. K Wuoso- 58 Of the methods of cure Wuososver thoroughly confi- ders all the circumftances of this fubject, which I have hitherto ex- plained, muft juftly wonder how the learned Dr. Boerhaave could be in- duced to hope, that fome time or other, a /pecific antidote may be found againft this contagious poifon(t Wy that is, by which it may be fo thorough- ly deftroyed, that though it had been received into the body, it may not produce the difeafe. But the principles and elements of things are fo certain, and fo well efta- 2 by the permanent laws of jature, that whofoever would en- re our to change them, would a& like thofe philofophers by fire (as they ftyle themfelves) who labour hard to tranfmute Te bafer metals into gold; and when continual dif- appointments have convinced them (1) Aphor. de cognofcendis et curandis morbis, 1390; 91; e? 92. of in the [mall pox. 59 of the vanity of their hopes, actu- ally extract gold out of the purfes of the ignorant and eredulous by the fumes of their charcoal. Tuis one obfervation I muft add, that there is no fpecies of fever, which requires the body to be tho- roughly cleared of the remains of the difeafe, more than this. Where- fore, upon the patient's recovery, blood is to be drawn, if his ftrength will bear it ; and cathartics are to be given feveral times at proper inter- vals. After which, the body is to be reftored to its former {tate by a courfe of milk, efpecially that of affes, with fuitable food, and the air and amufe- ments of the country. I suai clofe this long chapter with the account of a very malig- nant {mall pox in a youth of fifteen ears of age, communicated to me by my fon-in-law, the learned and K 2 ingenious 60 = Of the methods of cure ingenious Doctor Wi/mor; who, from the fifth day of the difeafe, attend- ed the patient jointly with Doétor Connel. . In the beginning of the fever pre- ceding the eruption, the patient was directed to be let blood, and to take a vomit, and the next morning a gentle purge: the day following, the {mall pox flufhed out. The pu- ftules were very numerous and {mall all over the body, looking more like a rank meafles than the {mall pox. As his fever ran very high, he was ordered draughts of Ga/coign’s pow- der with witre, to be taken ever fix hours; and to drink plentifully of arley-water acidulated with Spi- rit of vitriol. Ow the fourth day of the eru- ption, as he was very delirious, in order to procure {leep, a paregoric of fix drachms of diacodion was given in the fmall pox. 61 given him, which did not produce the efted. Tue fifth day, there was not the leaft {welling of the face; his pulfe was quick and full, his heat in- tenfe, and the delirium not abated. Wherefore he was ordered another bleeding ; the nitrofe draughts were continued, with the addition of Gve grains .of myrrh to each; as lilce- wife Jarley-water with Spirit of wvi- triol, and the paregoric as before. Te feventh, the appearance of the difeafe was ftill the fame, with the addition of an opprefflion of his breath, and a very troublefome dry cough. Dtafcordium was added to his nitrofe draughts, and he was ordered a folution of Lum ammoniac to be taken, a f{poonful at a time, as occafion required ; and the pa- regori¢ continued. THE 62 Of the methods of cure Tue eighth, he complained much of a moft acute pain in his head ; his fhortnefs of breath and cough were increafed, his pulfe low, and there were no figns of fuppuration ; nor the leaft {welling in the face or hands: but the fkin of his face looked like a piece of parchment. Blifters were ordered to be laid on his arms and legs, and platters, made of equal parts of the cephalic and blifering plafters, to be wrapt round his feet: likewife draughts containing of mithridate half a drachm, and of volatile falt of am- ber half a fcruple, to be taken every fixth hour; and a gargle of peéfo- val decoétion, and oxymel of {quills. Tue tenth, as every thing was grown worle, befides continuing the fame medicines, 4//fers were order- ed below the elbows. THE in the {mall pox. 63 Tue eleventh, his pulfe being much lower, and the patient much weaker, a mixture with Raleigh’s confection was ordered to be taken often by fpoonfuls, and the other cardiacs continued. On the twelfth, the pulfe being {carcely perceptible, and his breath opprefied to the laft degree ; when all hopes of fuccefg were given up, a fit of coughing, in which he was almoft fuffocated, brought on a {pitting of a limpid, fetid humor, equal in quantity to a falivation raifed by mercury. And this flux continued twelve days without any apparent abatement : from thence it gradually diminifhed for four days, when it ftopped entirely. By the fixteenth day, the difeafe, together with that difcharge, had fo far exhaufted him, that he was {carce able 64 Of the methods of cure able to turn in his bed: and yet his {pirits were fo much better, that he could take plentifully of liquid nourifhment. Whereby gathering ftrength, his fever had now the ap- pearance of a hectic only ; for which he was ordered to lofe five ounces of blood, to take draughts of /emon- juice, and falt of wormwood, with a little /perma cezi diffolved in them, every four hours, and to drink affes milk.every morning. By this method, with the repe- tition of Aleeding to five ounces two or three times, and now and then purging him gently with rhubarb ; together with elixir of vitriol in Briftol-water, and the country air, he in time happily recovered. In this cafe we have a moft re- markable inftance of what I have already in the {mall pox. 65 already faid more than once, that is, how folicitous nature always is, at any rate to expel the poifonous matter of this difeafe out of the body. L CHA P. C HA P. Iv.. Of accidents in the Jmall pox. ANY fymptoms and circum- M {tances attend the fmall pox, which, as they neither commonly occur, mor feem to depend on the nature of the difeafe, either affright, or perplex the phyfician. Where- fore it may not be impreper to make fome remarks concerning them. SoMETIMES the patient is feized with convulfions, juft before the eruption. But this {ymptom is more terrifying than dangerous; and in children particularly, thofe conyul- fions, which frequently come on be- fore the diftemper appears, are ge- nerally rather a good, than a_ bad fign, in the fall pox. 65 fign. Now in this cafe, though it may feem ftrange, blood-letting is to be carefully avoided ; but a blifter is to be applied to the neck, and to the foles of the feet pla/fers made of equal parts of the cephalic and blif~ tering plafters : not forgetting at the fame time to give thofe medicines inwardly, which - experience "has fhewn to be antifpafmodic. Of thefe the chief are, wild Valerian F00t Ruffian caftor, and the Spirits and volatile falts, chemically extrated From animals. For it has been fre- quently obferved, that, upon draw- ing blood in this cafe, the difeafe ended fatally. I can aflign no other reafon for this event, but that thofe involuntary motions are occafioned by the patient’s weaknefs ;_ which is fo increafed by that evacuation, that nature becomes incapable of throw- ing out the morbid matter upon the fkin. But the thing is otherwife in L 2 adults, i s P| | i Hi i { 68 . Of accidents adults, who, if not too weak, ought to lofe a moderate quantity of blood, and then be put into the foregoing method. Tue difeafe begins fometimes in a different, and almoft contrary man- ner. For the eruption appears with- out much fever or pain; for which reafon there feems to be no danger. But that fond fecurity is very fre- quently ill-grounded. For at the time when the puftules ought to tend to maturity, as if nature were lazy, and not attending to her du- ty, there is no fuppuration made: hence the fever increafes, with in- quietude of body, anxiety of mind, difficulty of breathing, and a de/i- rium ; which carry off the patient in a few days. In this ftate, the fever ‘ought rather to be raifed than checked ; and therefore warm me- dicines are to be directed, which promote in the {mall pox. 69 promote fuppuration, by increafin the motion of the blood, and thin- ning the humors: fuch are the Vir- ginian {nake-root, the Contrayerva- root, faffron, afa fatida, myrrh, and the like. But above all, 44/fers muft be laid on all the limbs. Such is the neceflity of {ome evacuation or other in this difeafe, that if the matter of the infection be over-abundant, as it happens in bad cafes, nature ne- ver fails endeavouring to throw off the load. Thus in adults a {pitting comes on upon the farft days of the eruption; whereas children, who feldom fpit, have a loofenefs almoft through the whole difeafe. Both thefe evacuations are of great impor- tance, and therefore as the loofenefs is not to be inconfiderately ftopped. in children; fo in adults, if the {pit- ting does not go on to our withes, it ought to be promoted by medi- ro) cines, which ftimulate the glands of the "0 Of accidents the mouth ; efpecially gargles made of a decoction of muftard feed and pepper, with the addition of oxymel. For in the confluent and malignant fmall pox, if this flux does not arife, and even continue to the end of the difeafe, it is a very bad fign, SoMETIEs a {uppreflion of urine makes the patient fufter great -pain, receiving little or no relief from diuretics. In this cafe Dr. Sydenham directed, that he fhould be taken out of bed, and expofed to the cool air : which generally has a good effe@. But the moft convenient method will be, to open the body by a cly- Jter, efpecially if, the puftules now appearing, there be any fear of tak- ing cold ; and then to infift a lit- tle on diuretic medicines; for which purpofe Glauber’s Jalt is particu- larly ufeful, as it is both laxative and diuretic. WHEN- in the fmall pox. 7 WHENEVER a woman with child Is feized with the {mall pox, the phyfician may juftly dread the con- fequences. For he has reafon to fear a mifcarriage, which expofes his pa- tient to two forts of danger, the one from the new fever, which attends that accident; the other from the lofs of blood, which may bring her very low. And therefore the farther fhe is advanced in her pregnancy, the greater rifque the runs ; « becaufe the delivery of a large child caufes a greater flooding than that of a {mall one. I can however affert from my own knowledge, that a certain woman was delivered of a fon at the full time, while the was actually la. bouring under this difeafe ; and yet both the mother and the child did well; but this is a cafe equally ex~ traordinary and fortunate. But {till a good deal depends on the time of the difeafe, when the abortion hap- pens : 72 Of accidents ens: becaufe the weaknefs occafi- oned thereby is the more dangerous, the more nearly it coincides with the time of the ripening of the puftules. Wherefore, if the efux be more than nature ufually requires, thofe medi- cines are to be given, which I have propofed in the d/o0dy {mall pox. Now, whereas thefe cafes fall out various ways, and phyficians have been divided in opinion concerning fome of them; it may not be im- proper to make fome animadverfions on them feparately. Wuen a woman in the {mall pox fuffers abortion, the child moft com- monly comes into the world with the diftemper on it; but not al- ways. The reafon of this difference will eafily be underftood, by duly confidering what I have already faid concerning izfeéion (1), and com- (1) Chap. i. paring in the [mall pox. 73 paring it with what I fhall hereaf- ter fay concerning the ivoculation of the {mall pox (1). Whereby it will plainly appear, that the feeds of the difeafe are fubtile particles, exhaled from the puftules come to n aturity ; which do not produce the*effect, till eight or nine days after their en- trance into a found body. Upon which account, when the child comes into the world, before mat- ter is made in the puftules on the mother, it has no vifible marks of the diftemper. And thus it fome- times happens, that the {mall pox, which the infant has contraéted in the womb, breaks forth on the fe- cond, third, or any other day’before the eighth from the delivery, whe- ther the child be come to its full time, or not; as will appear by the following cafe, which lately fell un- der my own obfervation. (i) Chap. v. M A Lapy 74 Of accidents A L aADy of quality was, in the feventh month of her pregnancy, feized with fo malignant a fort of the confluent {mall pox, that there was no appearance of any one fa- vourable fymptom. For fhe neither {pit plentifully ; nor did the {well- ing of the hands or feet come on, upon that of the face fubfiding ; nor in fine was fhe affifted by a flux of urine on the decline of the difeafe ; but on the contrary, her face was all covered with {mall ‘pimples, which made little or no matter. In this condition, fhe was, on the eleventh day of the diftemper, pretty eafily delivered of a fon, who brought no marks of the infection into ee rorld ; and fhe died on the fourteenth day. But in the morning of the fourth day following; the infant was feized with convulfions, the forerunners of the eruption, which pair as the fame day, and he died in the even- ae in the {mall pox. a6 ing. Inthis cafe it is plain, that fome fuppuration having been made, as ufual, on the eleventh day ; the diftemper paffed from the mother to the child, which was not to break out till eight days after. But in cafe there is no mifcar- riage, the child will be free from the difeafe during his whole life ; unlefs he happens to be born before the puftules were come to maturity. For as fomething naturally inherent in our conftitution renders the body liable to the infeGtion ; fo, when this debt is once paid to nature, we are fecure ever after. But the infant in the womb fometimes catches the diftemper, without the mother be- ing affected ; as I fhall prove by this remarkable inftance, which I well remember. A cértain woman, who had formerly had the fmall pox, and was now near her reckon- ing, attended her hufband in the M 2 diftemper. 76 Of accidents diftemper. She went her full time, and was delivered of a dead child. It may be needlefs to obferve, that fhe did not catch it on this occafion: but the dead body of the infant was a horrid fight, being all over co- vered with the puftules ; a manifeft fign that it died of the difeafe, be- fore it was brought into the world. Wherefore, upon thewhole, let none entertain the leaft fufpicion, that the fame perfon can poflibly have this diftemper twice. But the reafon why the body is liable to the in- fection once, and no more, is to me as entirely unkhown, as to the moft ignorant of mankind. But this I will add, that an infant in the womb may have the good re to go through the difea ade. and the: marks We quite effaced before i birth (1). (1) Vid. Mauriceau, es a Lroffeffe et Paccou- chement des femmes, Obf. From in the {mall pox. a7 From what we have faid concern- ing. abortions, it is ea fy to compre- hend what judgment ought to be formed of the monthly evacuations coinciding with the fmall poxece circumftance, at which people are apt to be alarmed. For this eva- cuation is of the fame kind with the flooding, which follows upon abor- tion: and whether it happens at the ufual time, or is brought on ir- regularly by the extraordinary ef- fervefcence of the blood; in both cafes, it rather affords selief than threatens danger. However, if in either cafe the difcharge fhould prove fo great, as to weaken the patient over much; it muft be re- {trained by thofe medicines, which I have recommended in the dloody {mall pox, without neglecting to draw blood, if requifite. But we know by experience, that women have fometimes uterine difcharges thro’ the whole courfe of the dif- F ; 78 Of accidents eafc, without lofs of ftrength, or any other inconvenience. Tue fame judgment may be formed of hemorrhages at the nofe, which frequently occur in the be- ginning of the diftemper ; for they are occafioned by the rarefaction of the blood in the {mall veffels; and therefore, by diminifhing the heat, are generally more ferviceable than detrimental, unlefs they run to ex- cefs, Ir happens fometimes, tho’ not often, that the variolous fever is ac- companied with a fingle or double tertian intermitting fever; in which cafe, the Peruvian bark, or, which is More convenient, i/s extraét, is to be given at proper diftances of time, till the paroxyfms ceafe to return, Nor is there any reafon to fear, that this medicine will hinder the maturation of the puftules: on the contrary, d/ in the fmall pox. 79 contrary, as this new effervefcence of the blood, and commotion of the humors, may eafily prove an obftacle to the fuppuration; by checking thefe, all things proceed in their ufual courfe. But firft, the body is to be opened by a cly/fer. Now the cafe is much the fame here with refpect to this febrifuge, as in mortifications, in which it is known to be of fignal fervice(1): and it was from a reflection, that mort'fica- tions are always accompanied with a fever, that I have propofed the fame medicine in the d/ody {mall pox, interfperfed with black fpots, or in other words, with {mall gan- grenes (2), Here it may not be improper to lay down one general rule, which is, that whatever acute difeafe comes (1) Vid. Medical Effays, Edinb. vol. v. part te artic. 10. (2) Chap. iii, upon } | " Sree Hs Se 80 Of accidents upon the {mall By requires to be treated with its own peculiar medi- ° 7 i wey | | cines, and octal bears them very well. By this time, I hope I have thrown fufficient light on the moft material circumftances of this part of my fubje&t. But before I clofe it, it feems well worthy of notice, that this difeafe is generally very mild, when it is contracted foon after fome confiderable evacuation, whether natural or artificial. Thus a wo- man in chi ots bed has generally a kindly fort of the fmall pox; if the has Secidered fomewhat of ftrength, by the time fhe is feized with “the diftemper ; and therefore reaps be- nefit from her late fufferings. The fame thing may be faid of fuch as are newly recovered from fome acute difeafe. And I have formerly feen many patients in the hofpital, who in the {mall pox. Sr who, after falivation for the venereal difeafe, caught the fmall pox, while they were yet vaftly emaciated; and all of them went through it with great fafety; a manifeft proof, that any evacuation, by withdrawing fuel from the fire, agrees particularly well with this difeafe. Laftly, to all that I have hitherto faid, this one remark more is proper to be ad- ded. ‘Though this be naturally a dreadful difeafe; yet it is fometimes found to produce very good confe- quences. For in conftitutions, where the blood is vitiated, either from an original taint, or by the manner of living; and glandular tumors are occafioned by the vifcidity of the lymph; the {mall pox, by purify- ing the juices, contributes to a bet- ter {tate of health for the future. N CHAP, 82 Of the inoculation BofA Se* SN 0 Sa Oa R OPA SE Ge Oe Ob 6 * Reais ® Rea ea een CHA. BY. Of the inoculation of the {mall pox. HE cuftom of inoculating, or transferring the {mall pox from an infected perfon to one that is found, has prevailed among us for fome years. ‘This matter has drawn our phyficians into parties ; fome approving, and others difap- proving, this new practice. J fhall therefore freely interpofe my opi- nion in the cafe. Our nature is fo formed, that al- tho’ we are always inclined to avoid whatfoever may be hurtful; yet, when any evil is to be undergone, which can only be fuffered once, this we are impatient to go through, even of the fmall pox: 83 even with a certain boldnefs:. with this view, that the remainder of life may be pafied without the unea- finefs which arifes from the conti- nual apprehenfion of its coming upon us, Ir having therefore been found by experience, that no body was feized with the {mall pox a fecond time, and that fcarce one in a thou- fand efcaped having it once; men began to confult how the dif- eafe might be communicated ; it manifeftly appearing to be eon gious, and it was obvious to con- jecture, that the feeds of that con- tagion lay hidden in the puftules. But FE have often wondered, how fuch a notion could come into the heads of ms almoft quite ignorant of what relates to phyfic. For, as far as | have been able to N 2 find 84 Of the inoculation find out by inquiry, this was the invention of the Circaffians, the wo- men of which country are faid to excel in beauty; upon which account, it is very common, elpe- cially among the poorer fort, to fell young ‘girls for flaves to be carried away into the ee pits parts. When therefore it was ob- ferved, that they, who were feized with this diftemper, were in lefs danger both of their beauty and their life, the younger they were ; they contrived this way of infeGing the body, that fo the merchandize might bring the greater pr ofit. Nei- ‘te did the thing require the af- fiftance of a phyfician or furgeon. It was fufhcient to make a {mall wound in the fkin, in any part of the body, and put into it a very little of the matter taken out of the ripe puftules ; and this even the women had of the {mall pox. 85 had learned to praétife (1): in like manner as our artifts now, making a very flight incifion in each arm, and putting upon it a {mall thread of lint or cotton, imbibed with the corruption, very rarely fruftrate the hopes of their defirous patients. In procefs of time, not many years ago, this art began to be ufed at Conftantinople, and Smyrna; not by the Zurks, who, imagining all things in life to come to pafs by un- avoidable fate, think it impious to oppofe and refift it; but among the Grecians, Armenians, and the peo- ple of other countries living there, who gave the knowledge of it to our countrymen (2). (1) See Philofopbical tranfactions, N°. 339, and 34.7. the {mall pox, London, 1722. Et Differtatio medica de Byzantina va~ riolarum incifione, uc- tore Le Duc. Lugd. Bat. 1722. (2) See Maiiland’s Account of inoculating Bur 86 Of the inoculation Bur that I may omit nothing re- lating to this affair; a learned au- thor (1) has given an account, -that the practice of /owing this difeafe, as they call it, has been known to the Ghinefe above thefe hundred years ; and that they do it in another man- ner, which is this. They take the fkins of fome of the dried puftules, which are fallen from the body, and put them into a porcelain bot- tle, ftopping the mouth of it very clofe with wax. When they have a mind to infeét any one, they make up three or four of thefe fkins, put- ting between them one grain of mufk into a tent with cotton, which they put up the noftrils. I+ was indeed not difficult for fuch ingenious people, when they faw thofe, who were converfant (1) Vid. Lettres edifiantes et curieufes des Mif= Jionaires, Recueil xx. page 304. with of the fmall pox: 87 with the fick, contraét the fame infection, to guefs that the air, taint- ed with the foul breath of the dif- eafed perfon did, when drawn in, corrupt one,’ who was found ; and therefore, they might rationally ar- gue, that the fame contagious mat- ter might be taken in at the no- ftrils. Nor were they miftaken in this point. Ir is however certain, (whatfo- ever the author of this narration, more {killed in theological than in medical learning, may ‘fay to the contrary) that this Chinefe way of implanting the diftemper is attend- ed with much more danger than the Grecian one. For the morbid par- ticles infpired violently offend the brain, by reafon of its nearnefs to the nerves, which perform the of- fice of {melling ; and we have in another place. proved, that conta- gion “aan i ! { ne u aha aie Ay } ‘Rt vd “i ait i alg 4 Hi, iil We WH) he J im | isi | ee ay ie 2 if f tif Qi ii {\ = SS SS rae 88 Of the inoculation gion is propagated, not by the blood, but by the nervous liquor (r). I mysetr have had an opportu- nity of making an experiment to this purpofe. For, when in the year 1721, by order of his facred Majefty, both for the fake of his own family, and of his fubjedts a trial was to be made upon feven condemn- ed malefactors, whether or not the {mall pox could fafely be commu- nicated by inoculation; I eafily ob- tained leave to make the Chine/e ex- periment in one of them. There was among thofe, who were chofen out to undergo the operation, a young girlof eighteen years of age; I put into her noftrils a tent, wetted with matter, taken out of ripe pu- ftules. The event anfwered ; for fhe, in like manner with the others, who were infected by incifions made (1) Introduéiion to the mechanical account of poifons. in of the fmall pox. 89 in the fkin, fell fick, and recovered ; but fuflered much more than they did, being, immediately after the poifon was received into the nofe, miferably tormented with fharp pains in her head, and a fever, which ne- ver left her till the eruption of the puftules, Stnce that time, this practice has been followed, without much fear, and indeed (as it ufually hap- pens in new experiments) fometimes with a degree of rafhnefs ; as pro- mifing a milder kind of fmall pox, than when taken in the natural way. For, by the accounts colleéted by thofe, who have inquired into the affair, it is plain, that fcarce one in a hundred dies by the inoculated {mall pox ; whereas many more in proportion are deftroyed by the or- dinary difeaie (1). (1) See Dr. Furin’s | between the mortality Letter toDr.Cotefworth, | of the natural {mall containing a comparifon | pox, and. that by ino- A RE- gO Of the inoculation A REMARKABLE inftance of this difference, and with what fecurity this tranfplanting the diftemper may be made, is given in the following relation, communicated to me by a gentleman of great credit. He was amerchant at Sv. Chriftopher’s, in the Weff-Indies, and in the making of fugar, (which jis the trade of that place) employed a great number of flaves. Ih one year, when the {mall pox raged with more than ordinary violence in the neighbouring iflands, with his own hands, he inoculated three hundred of them, from five to thirty years of age, with fuch fuc- cefs, that not one of them died, though moft of them were negroes, And whereas all the Awericans fuf- fer this diftemper in a moft terrible manner ; yet experience fhews, that it is much more dangerous, when it attacks the natives of Africa. culation. And his ae- inoculation in the years eount of the fuccefs of | 1724, 25, and 26. THINGS of the fmall pox. Or Tunes being thus, it may be proper to confider, whether any reafons can be alledged to. the con- trary. And, in the firft place, there are fome, who _infift upon it, that the eruptions produced by inocula- tion are not the genuine {mall pox, and confequently, that they cannot fecure any one from having the dif- eafe hereafter. Moreover, they take pains to bring teftimonies of pati- ents, who, after having undergone the artificial diftemper, have never~ thelefs been afterwards {eized with the true one. Now, I own, I cannot underftand how contagion, that Is, the ver feed of the difeafe, thould produce, not its own proper diftemper, but another of a quite different kind, Neither certainly does it matter, by which way the infe@ion is received, provided it brings forth manifeft marks of the difeafe. And as to O 2 thofe, 92 Of the inoculation thofe, who, after having been ino- culated with fuccefs, are notwith- ftanding this, faid to have fuffered the fall pox ; I muft proteft, that, after the moft diligent inquiry, I have not been able to find out one convincing proof of this kind. I very well know, that a ftory is {pread abroad, particularly by a late au- thor, of a boy, upon whom, about three years after he had contracted the difeafe by inoculation, it broke out again. But I am well affured, that this narration is of doubtful credit; and that there were fome of the family, who afhrmed, that no {mall pox appeared upon the ino- culation; that the parents (as we eafily believe what we with) de- ceived themfelves, and that the by- ftanders did not care to take away from them this pleafing miftake. Bur of the {mall pox. 93 Burt to fpeak plainly, if fuch a thing happened once, why do we not fee it come to pafs oftener? Or what can a fingle example, fuppof- ing it to be true and certain, avail, when innumerable experiments have produced nothing like it ?. However, fome men are infeéted with an in- curable itch of writing, and take great pleafure in contradicting others, to whom they bear envy. Let us therefore give them leave to applaud themfelves, and enjoy their own yain-glory, Bur they will ftill go on to ter- tify us, by faying, that there is dan- ger left, together with the {mall pox, fome other infeétious difeafe, inherent in the blood and humors of the fick perfon, fhould be tranf- mitted into the found body ; all contagion being very fubtile, and wonderfully active, . And it is in- ) deed 94. Of the inoculation deed not improbable, that {ome other diftemper, befides thofe which are cutaneous, may, by fucha way as this, get admittance into the fkin; and fuch perhaps are {cro- phulous {wellings, and the venereal difeafe. Yet I can hardly believe, that it ever happens, that the feed of one diftemper thould bring along with it mixed, the procreative mat- ter of another, of a nature quite dif- herent tronsait, However it be, it would be madnefs in a phyfician, without any choice, to take the morbid matter for this purpofe, out of fick bodies, without diftinGion, The moft proper fubjects are infants or children, found in all other refpects, as far as can be judged, - and born of healthy parents. Be- fides, it is, in MY opinion, more material, into what kind of a body the venom be infufed, than out of what it be taken. And this J the rather of the Jinall pow. Qs rather mention, becaufe I have more than once known rath and unwary furgeons to implant the difeafe into bodies weak, and of an il habit, with a fatal event, Laftly, it is of very great confequence to take care not to throw a new infeétion into one already infected : for I have obferved this to prove mortal; na- ture being oppreffed and finking under a double difeafe, when per- haps fhe might have got the better of either of them fingle, I nave often confidered for what reafons it is, that the inoculated is fafer than the natural {mall pox; and the following feem to be the chief. Firft, the venom is commu- nicated to a young, healthy, and, for the age, {trong body. In the next place, the violence of the fever, which follows, is prevented, if there be occafion, by bleeding, and gen- tie 96 3 —>—OOf the inoculation tle purging. And laftly, throtigh the whole time, that the contagi- ous matter is exerting its malignity upon the humors (which is gene- rally eight or nine days) quietnefs, moderation in diet, and every thing elfe is ftrialy obferved : whereas, many incur the natural diftemper on a fudden, when the blood is heated with wine and exercife ; by which means, all the fymptoms muft neceflarily prove more fevere and dangerous. Some have alfo been of opinion, that the difcharge out of the wound made to introduce the purulent matter, and likewife from the {mall pimples which break out round it, may contribute fomething to the fafety of the patient. But the {mall quantity which runs out this way cannot, I think, avail much. Two bifers laid, one to an arm, the other to a leg, will certainly do much more; efpecially if they be kept of the /mall pox. 97 kept running throughout the whole courfe of the difeafe. And I make no queftion, but this practice would be of very great fervice. Ir is proper to mention, that this artificial difeafe is ufually fo mild, that it {carce requires any help from medicines. But where it hap- pens otherwife, as it fometimes does, the fame will be neceffary, which have been direéted in the {feveral kinds of the natural {mall pox. T o conclude; it ought not to be omitted, that boils, and fwellings under the ears, and in the arm- pits, arife more frequently after the diftemper procured by art, than after that which comes of its own ac= cord ; for this reafon, as I fuppofe, that the venemous matter is pulhed forward with lefs force, which dif- advantage nature makes amends for this way. Therefore, all pofli- r ble 98 Of the inoculation, & c. ble means are to be ufed to ripen fuch tumors, of whatever kind the are: if this cannot be done, they muft be opened by incifion; and when all the matter is drawn out, the body muft be purged by proper medicines, which are to be oftener repeated in this, than in the natural difeafe, ct CHAP. Of the meafles. 99 EOANED IE HEIR XK OK GIR ICH Givi See ween PeeORe ILOS Cor wer. ee Of the meafles. BP NHE meafles have a reat af- finity with the {mall pox 5 being originally bred in the fame country, propagated in the fame manner, by infedtion, into diftant parts of the world, and never f{eiz- ing any perfon more than once. Tue hiftory of this difeafe, as it generally appears among us, Doétor Sydenham has defcribed with his ufual accuracy, calling it ¢ fever, which in its nature and method of cure agrees very much with the Small pox ; that is; accompanied with a great inflammation, and in which puftules of a particular kind are thrown out upon the fkin. Pa Now 100 Of the meafles. Now this inflammation does not only affect the furface of the body, but the inner parts alfo, and par- ticularly the lungs: hence follows a cough, with a difficulty of breath- ing. And although the diftemper in its nature be lefs dangerous than the fmall pox, and continues a fhorter time; for it ufually is ended in fix or feven days, or, at the far- theft, in eight, very thin, and light {cales, like fine flower, falling off from the fkin at that time ; yet it feizes with more violent heat, and greater anxiety than the other does. Therefore Rhazes obferved, that the inflammation of the whole body, the inquietude, and anxiety of mind, are much more terrible in: the mea- fles, than in the {mail pox (1). I wave therefore often wonder- ed, why that fagacious and experi- (4) See bis book, at the end of ibis. Chap. i. enced Of the meafles. TOL enced phyfician, whom I have fo often mentioned with praife, did not prefcribe bleeding in the very beginning of the difeafe; but neg- lected this material part of the cure o far, that he only ordered it at the end, when a hot regimen, and too warm medicines, had brought upon the patient a cough and fhort- nefs of breath. Efpecially fince he himfelf takes notice, that the loofe- nefs, which often follows this fe- ver, and which, he fays, proceeds from hot vapors from the inflamed blood falling upon the bowels, is only to be cured by blood-letting (1). But the great man deferves pardon upon this account, that in thofe times, phyficians never attempted to take away blood in thofe fevers, which were attended with any eruptions, particularly in children, who are the moft liable to this kind of ill- (1) De morbillis, cap. v. page207. edit. 1685. nefs, Ae ee ee Se She tee es a ied es > 1O2 Of the meafles. nefs. Their reafon was, left that emptying of the veflels fhould hin- der the coming out of what was to be difcharged by the fkin. But dai~ ]y ly experience fhews, that this fear is vain, and that the event is quite contrary to what they imagined. T o come therefore to the cure ; as this peftilential difeafe is of kin to the {mall pox, it requires a ma- nagement not very different from the fame, which we have recom- mended in that diftemper. Blood muft be taken away in the, begin- ning, according to the age and ftrength of the patient. It is beft, if poffible, to do this before the erup- tion of the puftules; but, if they are already come out, it muft however be taken away. For the greateft dan- ger is an inflammation of the lungs, which cannot be prevented too foon. Therefore in the height of the fever alfo, Of the meafles. 103 alfo, although bleeding was not neg- leéted in the beginning, yet it is fome- times neceflary to repeat it. And in the laft place, at the end of the dif eafe, when the fkin is now growing dry, and the feales falling off, it will be a great error not to open. a vein again ; that by this means, a flux of umors upon the breaft and inte. {tines,"and the fymptoms of a hec- tic fever and confumption, may be happil y prevented. It is really a thing to be grieved at, that phyficians, in {6 great an inflammation of the whole furface of the body, fhould not always have lireéted this leflening the quantity, and thereby checking the heat of theblood. AndI mo of all won- der, that Dr. Morton, who took fox tice of the neceflity of this practice, when the difeafe was at the higheft, fhould abfolutely forbid it in its firft appear = TP Tn Tes 104 Of the meafles. appearance. But this phyfician’s judg- ment was perverted by a vain, and not rightly underftood, opinion of a malignity and venom infecting the animal fpirits ; which had fo poffef- fed his mind, that he thought of nothing more, than of throwing in- to the body hot medicines, called cordials, as auxiliary forces againft the fuppofed enemy (1). A bad ex- ample, and at the fame time a con- vincing proof, how neceflary it is, that a man fhould be inftructed in the principles of mechanic philofo- phy, before he applies himfelf to the art of phyfic. Tue diet ought to be the fame as is prefcribed in the {mall pox; taking particular care that the body be kept lax, rather than bound up, through the whole courfe of the di- {temper. (1) De febridus inflammatcrits, cap. iv. As Of the meafles. 105 As to remedies; to thofe cool- ing ones, which are directed in the other difeafe, muft be added fuch as abate the cough, and help ex- pectoration; particularly oily linfus and the pectoral infufion, of which, with the addition of a little wizre, the patient may drink frequently. Dottor Sydenham gave diacodion, even on the firft days of the illnefs ; but I think he was not cautious enough in this point; for all me-~ dicines of this kind thicken the hu- mors, ftreighten the breath, and retard the eruption of the puftules.’ Therefore, during the increafe of the diftemper, they are to be ufed very {paringly ; but at the latter end they are of great fervice: inafmuch as there is then a neceffity to quiet the cough, which, from the fharp defluxion upon the lungs, threatens a heétic fever and confum- Q. ption. 106 Of the meaffes. ption. But in the mean time, gen- tle purges are to be given at due in- tervals. Milk, efpecially that of affes, muft be drank. Change of air is alfo neceflary. And laftly, exercife, fuitable to the ftrength of the patient, is to be daily en- joined, I am afraid, left I thould feem _ vainly to court applaufe by the fol- lowing narration ; yet it is fo much to the purpofe, and fo happily con- firms what I have faid, that I muft beg leave to relate it. About forty years ago, the meafles raged with fo great violence in this city, that they proved more fatal than even the fmall pox. At that time, a phy- fician of great eminence came to me, defiring that I would inform him what method I followed in this difeafe. I afked him, whether or not he ufed to take away blood ? He Of the meafles. 107 He anfwering no, becaufe Syden- ham very feldom did it; I advifed him to open a vein in the begin- ning of the diftemper, or, if he was called in later, as foon however as he poflibly could: for, faid I, this difeafe always brings with it a peri- pueumony, which he very well knew ever required bleeding, Not long after, he met me again, returning me hearty thanks for my counfel, affuring me, that he had not loft one patient, whom he had treated in this manner. Since that time, this practice grew fo common, that it is now followed even by our apo- thecaries, In the laft place, it is proper to take notice, that, as was obferved concerning the fmall pox (1), that the difeafe is more or lefs tife, accord- ing as the feafon of the year and (1) Chap. ii, Qa2 ftate ee! ree: Pp vara as Sie 108 Of the meafles. frate of the air confpire with thg in- feGion; fo-the like happens in the meafles. And Dr. Morton relates, that in the year.1672, this diftemper was {o terrible, that in London there died of it three hundred every week (1), But I have at laft finifhed this little work : which tho” it may per- haps, to contentious and malevolent perfons give matter for calumny and finding fault; yetwill, [hope, prove eneficial to mankind, efpecially to our own countrymen. This is all I defire ; for the confcioufnels of having done right is beyond all praife, carrying with it its own re- ward: and this he always enjoys, who confults the public good, and by his actions fhews, that he thinks he is Not for bimfelf, but for the whole world barn (2). (1) Append. ad Exer. } (2) Non fibis fed toti ge- de morbis acutis, pag. \ witum fecredere munde. A276 Lucan L. ii, v. 383. 8 EHR, JOH HOR, OH Hh Cot eale dos Mele wath Rate aoe CON TENGZS Of the preceding TreatTisz, pres Page iii CGHAP. 4. Of the origin of the /mall pox. I CHAP. i, Of the nature and forts of the fmall pox. 13 CHAP. II. Of the methods of cure of the fmall pox. 32 GHA PTV; Of fome accidents which happen in = Jmall pox. GC HAP. Vv; Of the inoculation of the Small pox. 82 CHAP, VI, Of the meafles. 99 SOR, ea as le ORICIOIOIIORIIORIOKIOK OK RHAZE s3 TREATISE ON THE SMALLPOX AND MEASLES. RORICIIORIIOICO OOK PREFACE In the Name of God, Merciful and Gracious. pu-Bexer MouammeD, the fon A of Zacharias, faith thus: Ow a certain night, at a meet- ing in the houfé of a nobleman, of great goodnefs and virtue, and very fond of the explanation of ufeful fci- ences, that they might be made plain and intelligible for the pub- lic benefit ; the converfation hav- ing turned on the fmall pox, I then fpoke what came into my mind on that fubjeé&t. Which, when that great man (whom may God long referve for the good of mankind) had heard ; he defired, that I would write a difcourfe on that difeafe with fufficient aptnefs, folidity, and clear- nefs : ears disse Sree om eee eae 1I4 Rhazes's Preface. nefs: becaufe there had never yet been publifhed, either by the anci- ents or moderns, a fatisfactory ac- count of it. I THEREFORE compofed this trea- tife, hoping to receive my reward from the almighty and glorious God, as the effeét of hi: good will. Now this is the fum of its con- tents, and the heads cf the chap- ters. Crap. I. Of the caufes of the finall pox; and how it comes to pafs, that no mortal, except by chance here and there one, efcapes free from this difeafe. Cuap. II. What bodies are moft difpofed to the {mall pox: alfo of the feafons of the year, in . which they moft frequently hap- pen. Crap, Rhazes’s Preface. 115 Cuapr. III. Of the prognoftic figns of the eruption of the {mall pox and meiafles. Cuap. IV. Of the regimen, or cure of the {mall pox, in general. Cuap. V. Of prefervation from the {mall pox before the figns of them appear; and the way to hinder the multiplying of them after the figns have appeared. Cuap. VI, Of thofe things, which haften the eruption of the {mall pox: alfo how nature’is to be af- fifted therein. Cuap. VII. Of taking care of the eyes, throat, ears, and joints, as foon as the figns of the {mall pox have appeared. Cuapr. VIII. Of ripening the pu- {tules. Cuap. IX, Of drying tle puttules. CHAP. 116 Rhazes's Preface. Cuar. X. Of taking away the dry {cabs of the {mall pox, and the efchars from the eyes, and the reft of the body. Cuap. XI. Of deftroying the marks of the {mall pox. Cuap. XI. Of the food and diet in the {mall pox. Cuap. XIII. Of managing the dif- charges of the belly, in the fmall pox. Cuap. XIV. Of the curable and in- curable {mall pox and meailes. CHAP. Of the caufes, 8c. 117 "AoSR Ra SRO Me 0 ROR 6 Mode SR CHAP IL. Of the caufes of the {mall pox ; and how it comes to pa/s, that no mor- tal, except by chance here and there one, efcapes from this dif ease: alfo a brief account of what Galen fas mentioned concern- ing. it. S to thofe phyficians, who af- firm, that the moft excellent Galen has made no mention of the {mall pox, and therefore that he did not know this diftemper ; furely they have either never read his works at all, or only very curforily ; nay, molt of them do not know, whe- ther what he plainly fays of it, is to be underftood of that difeafe. For Galen, in a certain treatife, fays, this * * does good this and that Wa, 118 Of the caufes way, and alfo againft the fmall pox. And in the beginning of the four- teenth book Of pulfes, that zhe blood is putrefied in an extraordinary de-~ gree, and that the inflammation runs fo high, that it burns the fhin; fo that the {mall pox, and peftilent car- buncle, are bred in it, and quite con- fume tt. Anp inthe ninth treatife of the book Of the ufe of the parts, he ob- ferves, that the /uperfluous parts of aliments, which are not turned into blood, and remain in the members, putrefy, and in time increafing do fer- ment. whence, at laft, are generated the peftilential carbuncle, the {mall pox, and confluent inflammations. Lastxy, in the fourth part of his Commentary upon the Timeus of Plato, he fays, that zhe ancients gave the name orcyyory to every thingy which produces redne/s, as the car- buncle, of the finall pox. 119 buncle, and Jmall pox; and that thefe difeafes are bred in thofe, in whom bile abounds. Bur as for thofe, who alledge, that he has propofed no remedy or cure, nor explained the nature of this diftemper ; they indeed fay what is true: for he mentions no more than what we have cited. But God knows, whether he might not have done it in fome other books, which have not yet appeared in A- rabic. A's for my own part, I have with great diligence inquired of thofe, who underftand both the Syriac and Greek language, and defired them to inform me concerning this mat- ter: but not one of them could tell me more than what I have {et down, But this indeed I very much wonder at, and why he paffed over this dif- temper in filence; efpecially fince it 120 Of the caufes it was frequent in his time, and therefore there was great reafon for his prefcribing remedies againft it, as he was fo diligent in finding out the caufes and cures of difeafes. T ue moderns have, it is true, propofed fome medicines for the cure of the {mall pox, but not di- ftinétly and clearly enough ; neither has any one of them explained the caufe of it, and why, except here and there one, no body efcapes it; nor fhewed the methods of cure in a right order. Upon which account, I hope that the good man, who en- couraged me to undertake this work, will have his recompence ; and that my reward will be doubled, when I fhall have defcribed whatever is neceflary to the cure of this difeafe in due method, afligning to every thing its proper place; by the help of God, ; WHERE- of the {mall pox. 121 Wuererore let us begin to re. cite the efficient caufe of this dif- temper; and why it happens, that {carcely any one mortal efcapes it, And then we will purfue feparately, in the fubfequent chapters, the other things, which relate to it; and, with God’s affiftance, fhall fay on each head whatever is neceflary for its cure, Isaythen(z1), thatthe body of man, from the time of his nativity, till he arrives at old age, continually tends to drynefs ; and that therefore the blood of infants and children, and, in proportion, the blood of young men, abounds much more with hu- midity, than the blood of old men, and is alfohotter. And this indeed Galen teaches us, in his Commentaries upon the Aphorifms, where he fays : (1) Here begins the tranflation of the anonymous Greck interpreter. S the 122 Of the caufes the beat of children is indeed great- er in re ntity, than the heat of young Met 3 but the heat of young men is more Violent in quality. This alfo is evident from the force of their natura Ge ata as the digeftion of their food, and accretion in chil- ae THEREFORE, the blood of chil- dren may be compared to new wine, in which the fermentation leading to ripencfs is not yet begun: and the blood of young men to the fame, fermenting and emitting fteams, till It is quiet and ripe. And, laftly, the blood of old men is like towine, whofe f{trength is gone, fo that it thes comes vapid, and begins to grow four. Now, the {mall pox arifes, when the blood putreties nud te erments, and the fermenting particles are thrown out of it; the blood of children, like to new. wine, being changed to that of of the fmall pox. 123 of young men, which isas wine per- feétly ripened. And this fermen- tation and ebullition is the difeafe, Anp this is the reafon why chil- dren, efpecially males, rarely efcape being feized with it. For, without doubt, as the wine naturally fer- ments till it comes to perfection; fo the blood undergoes the fame alte- tation, in pafling from its firft to its fecond ftate. And there feldom hap- pens a temperament in an infant or child, in which fuch a change can be made in a {mall time, and with- out manifeft figns of it: as may be judged from their diet, which in in- fants is milk ; and in children, not milky, but their food is ftronger, in proportion, than that of other ages, and more compounded. ‘To which it may be added, that in thefe there is, after food, a greater motion of the humors. For thefe reafons, ee very 124 Of the caufes very few children go into life with- out this diftemper. Befides this, great alterations are made here, by different temperaments, manners of life, and habits ; as alfo, by the con- ftitution of the ambient air, and ftate of the blood, both as to quan- tity and quality: for in fome this flows quicker, in others flower ; in fome it abounds, in others it is de- ficient ; in fome it is very bad, in others in a better condition, As to young men, whereas the change in their blood is already made, its maturation finifhed, and the particles of moifture, which fhould caufe putrefaction, are now exhaled ; hence it follows, that this difeafe cannot be generated in them, at leaft but very feldom, that is, in fuch, whofe blood ftill abounds with too much humidity, or is very cor- rupt, with a violent inflammation ; : OF of the fmall pox. 125 or who, perhaps, when they were children, had been attacked with the chicken-pox, when their blood had not yet pafled from the firft fate to the fecond ; or, laftly, who have a moderate heat, thatis, without much moifture ; and when they had the chicken-pox, were of a dry tempera- ment, and lean, In an advanced age, the diftem- per will fcarcely appear, unlefs_per- haps in putrid, malignant, and pe- ftilential conftitutions of the air, in which this difeafe chiefly rages. For fuch an air difpofes bodies very much to heat and moifture; and an inflamed air’ promotes eruptions, by blowing up the fpirit in the ven- tricles of the heart, and communi- cating to it the like difpofition, which, by the force of the heart, is fent into the blood, which is in the arteries ; and 1260 86=— Of'_«the caufes, Se. and brings it into the fame ftate of corruption, Tuus we have fufficiently, though fuccinélly, treated of the caufes of the {mall pox. We fhall now pro- ceed to fhew, what bodies are moft difpofed to this difeafe and the meafles. CHAP. Of bodies difpofed, Sc... 129 : AK CE ND HEEL \S5 GORE OER COE SEO CHAP. IL Of bodies difpofed to the fmall pox. O DIES inclined to this difeafe B are generally fuch, as are moitft, pale, and flefhy ;_ the well-coloured alfo, efpecially, if they are ruddy and tending to brown, are difpofed to it, if they are loaded with eth, So are likewife thofe, who are frequently liable to acute and con- tinual fevers, to running of the eyes, ted pimples, and boils, Proceeding from the eating of fweet things ; as dates, honey, figs, grapes, and all thofe {weets, in which there is a grofs humor; particularly, thick gruels, food made of unground wheat, with honey and water, or a great quan- tity of wine and milk, Lean, 128 Of bodies difpofed Lran, bilious, hot, and dry bo- dies are more inclinable to the mea- fles, than to the {mall pox. But if they happen to be taken with the {mall pox, the puftules are either few, diftiné, and favourable ; or, on the contrary, very bad, irregular, deceitful, dry, with putrefaction, and no maturation. Lastiy, thin and dry bodies, of a cold temperament, are neither fub- ject to the {mall pox, nor to the meafles. And if they happen to catch the {mall pox, they have but few, in a moderate way, and without danger, with a very flight fever ; becaufe fuch conftitutions extinguifh ‘the difeafe in its very beginning. Tue feafons of the year, in which the {mall pox are moft frequent, are various: they rage moft at the lat- ter end of the autumn, and the be- ginning of the {pring; and when in to the {mall pox. 129 in the fummer there are great and frequent rains with continual fouth winds; and laftly, when the winter is warm, and the winds foutherly, Wuen the fummer is exceffive- ly hot and dry, and fucceeded by a hot autumn, in which rains come on very late ; then the meafles quick- ly feize thofe, who are difpofed to them, that is, thofe who are lean, hot, and of bilious conftitutions. Bur all thefe things admit of great differences, by reafon of the diverfity of countries and places, and occult difpofitions in the air, which bring on thofe diftempers, and ren- der bodies fubje& to them. And therefore, at fuch times, great dili- gence is to be ufed in the preferva- . tion from them; as we fhall fhew in the fequel. $2 CHAP, 130 Of the prognoftic figns fe Aa SOT ON RO MI ROM Hh I oe eG ee dates CTE Pe, Of the prognoftic figns of the eruption of the frall pox and meafles. a E eruption of the fmall pox is preceded by a continual fever, a pain in the back, itching in the nofe, and terrors in fleep. Thefe are the proper figns of the approaching {mall pox, efpecially the pain in the back, with a fever; and alfoa pricking, which the pa- tient feels all over his body; toge- ther with a fulnefs and rednefs of the face, which at times goes and comes; a rednefs of the eyes, a hea- vinefs of the whole body ; frequent yawnings, a pain in the throat and breaft, with a difficulty in breath- ing, and ftreightnefs in the gullet ; then a drynefs of the mouth, thick {pittle, of the eruption. 13t {pittle, a hoarfenefs of the voice ; head-ach, anxiety of mind, inquie- tude; fick qualms, and _heavinefs of heart: with this difference, that anxiety of mind, fick qualms and heavinefs of heart, opprefs more in the meafles, than in the fmall pox, unlefs the fmall pox be of a bad fort; for the meafles are from a very bilious blood. And, on the other hand, the pain in the back, the heat and inflammation of the whole body, efpecially in the throat, with a fhining rednefs, are more proper to the {mall pox than to the mea-~ fles. Wuerzrore, upon the appear- ance of thefe figns, or fome of the worft of them, you may be affured, that one or the other of thefe dif- eafesis nigh at hand. As to the fafer kind of the {mall pox; in thefe, the quantity of blood 2 is 132 Of the prignoftic figns Bc, is greater than its bad quality : and hence arifes the pain of the back ; the greater blocd-veffels, which are fituated near the vertebrae of the back, being diftended with too great a quantity of blood. CH AP. Of the regimen, or cure Bc. 13 IR ROIOIOK KOK NOOK FRIAR AOKI OOK HO HOOK KSI SKS See Crit AP. FV: Of the regimen, or cure of the fmall pox in general. HE firft article thall be of the = prefervation to be ufed, before the figns of the {mall pox appear ; and after they have appeared, how the difeafe may be leffened. Tue fecond, concerning the eru- ption. Tue third, the care to be taken of the eyes, ears, nofe, throat, and joints. Tue fourth, of the Tipening of the puftules. Tut fifth of their drying. Tue fixth, how the {cales and crufts 134 Of the regimen, or cure &c. crufts are to be cleared from the eyes, and the reft of the body, Tue feventh, of deftroying the marks. Tue eighth, of the diet in the {mall pox. Tue ninth, of regulating the dif- charge by the inteftines. Tue tenth, of curable and in- eurable {mall pox and meafles. Or each of thefe I fhall, God willing, briefly, but fufficiently, dif- courfe, CHAP. Of prefervation from, Bc. 135 ieee ee Seale anal athe bite alte atte ale alte a! OS 5 ee eee Of prefervation from, and leffening the difeafe. LOOD ought to be taken away B from children and young men, if they have never had the {mall pox, or have only had what is called the chicken-pox (efpecially at fuch feafons as we have above defcribed) before they are feized with a fever, and the figns of the difeafe appear. A vein may be opened in thofe, who are fourteen years old ; to thofe who are younger, cupping-glaffes muft be applied, and their lodgings fhould be kept cool. Ler their diet be yellow lentils, tarts made of unripe grapes, minced flefh-meat, drefled with vinegar and honey, or with the acid fyrup ; to which 136 Of prefervation from, and which raifins, a few figs, and chiches are fometimes added : alfo kid-broth, veal-jellies, and boiled wood-cocks and hens. But thefe mutt be mixed with the juice of un- ripe grapes. Tuerr drink fhould be water cooled with fnow, or clear fpring water cold ; with which their cham- ber may alfo be fprinkled. Let them frequently eat acid pomegranates, and the infpiflated juices of acid and aftringent fruits, as pomegranates, currants (1), and the like. Wuere the conftitution is hot, and there is a great inflammation ; barley-water, with a fourth part of and acid juice boiled to is Ribas, which alfo | two thirds, is called fignifies a fort of Aapa- | Rob de Ribes, See Go- thum acetofum, or for- | lit Lexic. rel, of which the red (1) The Arabic word acid lefening the difeafe. 137 acid pomegranate juice, may be drank in the morning. But if the heat be lefs, a ptyfan of barley, with fugar, is proper; and vinegar, len- tils, pomegranates, and the juice of unripe grapes, may be added to the food ; for all thefe thicken and cool the blood, and make the diftemper more mild. Tuts regimen is of great fer- vice in all times of peftilence ; for it diminifhes the malignity of pe- ftilential ulcers and boils ; and pre- vents quinfeys, pleurifies, and all diftempers arifing from bile and blood. Tue patient may go. into cold water, and fwim in it about noon. He muft abftain from new milk, wine, dates, honey, and, in general, from {weet things, and meats, made by a mixture of flefh, onions, oil, butter, and cheefe; from mutton, U beet, 138 Of prefervation from, and beef, thell-fith, high-feafoned things, and hot feeds. Inftead of thefe, in times of contagion, he may eat young birds; and if the temperament be hot and moift, liable to putrefaction, or hot and dry, and apt to be in- flamed; he muft eat as follows; that is, in the hot and dry confti- tution, cooling and moift garden- herbs, purflain, mallows, beet, gourds, cucumbers, forrel, and {mall pompions. As to fweet melons, they are for- bidden; and if any one by chance eats of them, he muft prefently drink a fpoonful of the juice of fome of the acid fruits. He may be al- lowed {oft fifth, and butter-milk. To the food of thofe, who are corpulent, flefhy, and of a ruddy complexion, fuch cooling and dry- ing things, as we have mentioned, may be added. They fhould all forbear leffening the difeafe. 139 forbear labour, fatigue, bathing, venery, walking or riding in the fun and duft, drinking of ftagnating waters, blafted fruits,or mouldy y herbs; i and ais figs and grapes: becaufe thefe drive the humors to the fkin, and, filling the blood with flatulent {pirits, difpofe it more to fermen- tation and ebullition. Their body muft be opened, if there be occa- fion, with the juice of prunes and fugar, or with whey and fugar, If the air be putrid and peftilential, their face may be continually fprink- led with the water of fanders and eamphire; which, if it pleafes God, will have a good effect. As to fucking infants ; if they are fat and ruddy, and above five months old, let them be cupped; and let the nurfe, as far as poflible, be ma- naged in the manner we have men- tioned, U 2 I coME 140 Of prefervation from, and I come now to thofe medicines, which thicken and cool the blood, and check its ebullition and putre- faction. Aut acid things are proper for this purpofe, efj pecially the water called A/-rdéib, that is, the four, bitter water, which fwims upon but- ter-milk expofed to the fun; and the acid juice of citrons. Tue fame intention is very well anfwered by many things, which have an aftringency joined with their aci- dity, and thereby condenfe the blood. Such are, four grapes, fumac, Rob ribas, or the infpiflated j juice of cur~ rants, apples, quinces, and pomegra- nates; jujubes, lentils, coleworts, coriander, lettuce, poppies, endive, night-fhade, fugar called Bambu (1), the feeds of fleawort, and camphire. (1) The Indian name for a concreted juice, like fugar, in an Indian reed. THE leffening the difeafe. 141 Tue following compofition is good to cool the blood, and reftrain the heat of the liver, and efferve- {cence of the bile. T ax ks of red rofes beaten, ten drachms; Bambu - fugar, twenty drachms ; fumac, the feeds of wild forrel, lentils peeled, berberies, the feeds of purflain, feeds of white let- tuce, of each five drachms; red fanders, two drachms and a half; camphire, one drachm. Let thefe be mixed, and give three drachms of this powder to the patient every morning in his drink, together with an ounce of the juice of wild forrel, or of ribas, pome- granate, or unripe grapes, and the like. Tue medicine 4/-/acangjabin, that is, oxymel with fugar, is like- wife good, which is thus prepared. TAKR 142 Of prefervation from, and T axe one part of red, fharp vine- gar, depurated ; two parts of rofe- water ; mix, and infufe in the cold mixture, one ounce of red rofes; half an ounce of balauftines; two ounces of pomegranate-peel, for the {pace of three days. Then ftrain the liquor, adding to it, according to the quantity of the vinegar, twice or thrice as much of the fugar #g- barzad, that is, white fugar-candy, Boil it fufficiently, and ule it. Ir will alfo be of ufe to take of rofes and bambu - fugar, of each ten drachms; white fanders, three drachms ; camphire, one drachm ; and moiften them with the muci- lage of - the feeds of fleawort ; then make the maifs into pills, or troches. Of thefe, at proper times, three drachms may be given in the patient’s drink, together ,with one ounce leffening the difeafe 143 ounce of the aforefaid 4//acangja- bin. Brsrpes thefe, the following fy- rup is excellent, and wonderfully exceeds in virtue all others, which I have feen tried; though per- haps the fyrup of pearls, which the Indians defcribe, and of which they boaft more than they can have experienced, may be more power- ful. For they fay, that 7f any one drinks of that fyrup, though nine puftules have already appeared, there will not come out a tenth. Now the compofition of mine is this. Taxe of red vinegar depurated, old, and fharp, three pounds; of the juice of acid pomegranates, the acid juice of citrons, the juice of unripe grapes, of ribas, of the Sy- rian mulberries, the -expreffion of Syrian fumac, and berberies, of each one 144. Of prefervation from, and one pound ; the juices of lettuce and tarragon, of each a quarter of a pound ; of the decoétion of red ju- jubes, and the infufion of lentils, each a pound and half. Mix all to- gether, and add three pounds of fugar ; boil the whole, and put to it fome of the fyrup already made, hot, working it with a peftil, till it is diflolved: then mix it with the whole, ftirring it continually with a flick of camphire wood; throw it into a mortar of ftone, or willow- tree wood, taking out the cleareft part all the while; having added and mixed bambu-fugar and cam- phire. Ufe this before the fmall pox appears, and alfo after the appear- ance, as we {hall direét anon. It is alfo proper in all diftempers, which arifé from a bilious blood, in peftilential ulcers, boils, quinfeys, and the like. Wuat leffening the difeafe. 145 Wuat I have faid, may in gene- ral fuffice concerning prefervation from the fmall pox, before the fe- ver, which attends their figns, comes on. Tue laft mentioned fyrup repels the difeafe from one, who is in fuch a condition, that it can be repelled ; fo that what comes out will be very moderate. It alfo effets, that the change of the blood from the firft ftate to the fecond, fhould not be done too haftily, and at once, with too great ebullition, and frightful and dangerous fymptoms ; but by degrees and in a longer time; in the way of maturation, not putre- faction, without terrible and dan- gerous fevers. Bur when the fever, whichaccom- panies the eruption, arifes, this regi- men is no longer to be ufed, unlefs with great caution and prudence ; for 146 Of prefervation from, and for a miftake here is very danger- ous, for this reafon, that while the blood is rarefied, and nature, ac- cording to the temperament of the patient, is endeavouring to expel the morbific matter ; if then the re- frigeration and condenfation, which you intend, does not exceed the cool ftate the patient was in before, it will happen, that the ebullition will break out a fecond or third time ; and thus nature will be dif- turbed in her work. Neither can that ebullition be checked, without great danger; for thofe remedies mutt be ufed for this purpofe, which do. in a manner congeal and coagu- late the blood; fuch are, opium, hemlock, a great quantity of juice of lettice, night-fhade, and the like. And the congelation of the blood, and ex- tinction of natural heat, by all thefe, is not fafe; becaufe of the excels, which is eafily committed: for it will leflening the difeafe. 14.7 will be hard, at the fame time to re- prefs the effervefcence, and _preferve the due natural heat. In one word, care muft be taken, not to extin- guifh preternatural and natural heat together. Now I fhall.communicate a prac- tice, which phyficians, either through ignorance or avarice, that they only may receive profit from it, ufually conceal; andit is this. When you obferve, upon the figns of the difeafe, a diftenfion of the belly, pain in the back, rednefs of the face and eyes, a violent head-ach, with a full pulfe, and alfo a ftreightnefs of breath, a red and turbid urine, and fuch a heat of the body, as a man feels, who has been for fome time in a hot bath; efpecially, if the body be flefhy ; there is then all the reafon in the world to take away blood. Wherefore, draw away a good quan- xX 2 tity, 148 Of prefervation from, and tity, even till the patient faints away It will be beft to do it from the bafi- lic vein, or fome of its branches ; but if that cannot befound, from the cephalic vein. Sometimes, when the bafilic does not appear, it may be taken away from the vein in the ankle ; but better from the bafilic omits branches, becaufe they draw from the greater veins in the abdo- men more than the cephalic does. Ir the fymptoms do not run very high, altho’ they are manifeft, draw blood, but fparingly ; and when they are lefs, take away very little. Then proceed in the cure with repelling medicines, as has been mentioned. Ir by thefe the feverifh heat is removed, and the pulfe and breath are come to their natural ftate; ftill infift on the ufe of them, till the heat of the difeafe is perfectly oa] € 3 leffening the difeafe. 149 ed, which will be done ina fhort time. In order more effectually to per- form this extinction, let the patient drink water, made cold in {now to the higheft degree, very plentifully and often ; fo that he may feel the coldnefs of it in his bowels. If, af+ ter this, the fever and burning re- turn, give this water, a fecond time, two or three pints, or more, in the fpace of half an hour. Ir ftill the heat return, and the belly be. full of water, make him vomit it up, and then give it again. And if the water finds a paflage, either by {weats or urine, you may be affured the patient is in a good. way. | Bur if the water does not pafs, and the heat returns as it was at firft, or even is more violent ; omit giv- ing 150 Of prefervation from, Sc. ing the water fo often, and have re- courfe to the other extinguents, which have been defcribed; and if the patient finds relief, perfift in the ufe of them. If, on the contrary, you perceive, that they. produce an intolerable uneafinefs and inquietude, you may certainly know, that the eruption of the {mall pox or meafles is at hand. | Wherefore you mutt quit this method, and haften to af- fift nature, in expelling her fuper- fluities, in the manner I fhall deliver in the following chapter. CHAS. Of thofe things, which, &c. 151 Naf SRO Ro SR 0 SR 3 SOR, KOON, SO Oe Oe OF One "Rea Kwai Ce Ret A PVE Of thofe things, which haften the eruption of the {mall pox. HE eruption of the {mall pox and meaifles is promoted by the followingmeans. The patient muft be well wrapped up in cloaths, and his body rubbed all over. He muft be kept in a room not very cold ; he fhould drink frequently, a little at a time, of cold water; to pro- voke {weat, and affift the protru- fion of the humors to the external parts. Tue fick perfon muft put ona double fhirt, the borders of which muft be bound. Underneath him, place two {mall bafons of very hot water, one before, and the other be- hind 152 Of thofe things, which hind him; fo that the vapour may come to the whole body, except the face ; by which means the fkin will be rarefied, and difpofed to receive the erumpent humor. For the fur- face of the body may, in this cafe, be compared to a leech, which, to cool its own heat, attraéts whatfo- ever it'can. And by this manage- ment, not only is the fkin foftened, but the ftrength of the patient is al- fo preferved: fo that nothing can_ be more proper. Ass to furnaces and baths, they are both deftrudtive at this time, by fo over-heating and weakening, that a {wooning follows ; by which na- ture is diverted from its work -with great danger, if the fit be violent and long: for nothing is a greater indication of the approach of death, the natural heat retiring into the inner parts; after which it will be foon haften the eruption. 153 foon oppreffed and extinguifhed by the over-abounding humors. Like- wife, when the hot vapour, which I have directed, is ufed, it muft ne- ver be fuffered to cool upon the bo dy ; but is prefently to be wiped and dried off, with great diligence. This method is abundantly fufficient to forward the coming out of the dif- eafe, when nature is not languid, or the humors too thick and vifcid. Bur in cafe it happens, that the outward fever is indeed mild, but anxiety and inquietude continue, and the eruption is difficult ; you muft wait till the fifth day is over, and then ufe thofe medicines which promote the eruption. But this is to be done with great caution, and all manner of attention, in the way which I have mentioned, when {peaking of the rules to be obierved in giving extinguifhing remedies ; for 154 Of thofe things, whith for an error here, although it be not {o great as the other, yet is alfo dan- gerous. And the caution confifts in not being too hafty in giving thefe medicines, but to infift upon the former regimen, as long as there is any profpect of fuccefs without them; and as long as you are not yet certain, that the fever is too re- mifs in the inward parts, as well as itis in the outward. This you will eafily know, by the pulfe and refpi- ration not being too quick, full, or irregular; and if, in feeling the breaft, you do not find it hot in the higheft degree. For though the fever be doubly or trebly increafed, it will not therefore be mortal; as you may judge by comparing this with other fevers, which you have obferved in perfons of the fame tem- perament, and in the fame degree of heat with your patient, who never- thelefs have recovered. ‘THESE haften the eruption. 155 Tues extinguifhing remedies are alfo to be applied, when, as foon as the puftules appear in the fkin, the patient feels himfelf to be pretty well, and his pulfe and breath are eafy. But if, on the other hand, the eruption goes on flowly and with difficulty, they muft be abfo- lutely forborn : for to ufe them, is to ftrive againft nature, and check the protrufion. And when any an- xiety follows upon the ufe of extin- guents, efpecially a palpitation of the heart, be fure that you~ haye committed a great error. You mult therefore immediately take all pof- fible pains in foftening the fkin, ig the manner I have taught; and give to drink frequently warm wa- ter, either alone, or in which fen- nel and {mallage- feeds have been firft boiled, and the like fimples, which conduce. to the eruption 5 according as the heat of the pati- Y 2 ent, 156 Of thofe things, which ent, and his ftomach will bear them; regard alfo being had to the flow- nefs of the pimples in coming out. Tus is the defcription of an ealy, gentle medicine, which, without too much heat, promotes the eru- ption. Taxe yellow figs to the number of thirty; raifins, the ftones being taken out, twenty drachms; pour upon them three pints of water, and let them boil till they are diffolved. Give to the patient of this liquor half a pint, at three feveral times. ‘Then cover him up well in cloaths, and foment the body, as is above directed. THE following is yet more pow- erful. Taxe of the aforefaid decoction four ounces; of the deco@ion of fennel and fmallage - feeds,’ two ounces ; haften the eruption. 169 ounces ; let the patient drink it, as has been direéted. One ftill more efficacious is this. Bort fennel-feeds and {mallage- feeds, of each ten drachms, in an earthen vefiel, till the water is red; {train it, and give three ounces at a time. Lastiy, this compofition is very good and ufeful, at feveral times. Take of red rofes four drachms ; of lentils decorticated nine drachms; yellow figs ten ; of gum tragacanth three drachms; of white raifins {toned ten drachms ; lack, cleared from its fticks, and wathed, three drachms; fennel and {mallage-feeds, of each five drachms. Boil all thefe in three pints of water, to one pint: Strain the liquor, and give half a pint of it, with a fixth part of a drachm POPE fm? 158 Of thofe things, which, &c. drachm of faffron, twice or thrice, as there may be occafion. We fhall now {peak of thofe parts of the body, of which care is to be taken. CHAP. Of taking care, 8c. 159 TPES SR a ie CH'A P. VIL Of taking care of the throat, eyes, Pe. as foon as the puftules have ap- peared. A S foon as ever the figns of the {mall pox appear, particular care muft be taken of the eyes, the throat, the nofe, and ears, and alfo of the limbs, in the way Iam going to defcribe. Nay, fometimes it will be neceffary to extend our care even to the foles of the feet, and the palms of the hands: for oftentimes violent pains arife in thefe parts, the hard- nefs of the {kin hindering the eru- ption. Upon the firft appearance of the figns, drop rofe-water into the eyes how and then; alfo wath the face with cold water often in a day, and {prinkle 160 Of taking care of the fprinkle the eyes with the fame. For if the difeafe be mild, this method will prevent the puftules breaking out in them. This ifideed is to be done, for greater caution ; for in the mild fort, it feldom happens, that any puftules break out on the eyes. But in a-bad fort, when you fee a large eruption in the beginning, with an itching of the eye-lids, and red- nefs of the white of the eyes, fome places of which are redder than o- thers; you may be affured that the {mall pox will break out there, un-~ lefs great help be given : therefore immediately drop rofe- water, in which fumac has been infufed, into the eyes, feveral times in the day. It will be ftill more effectual to apply a collyrium, made of galls in rofe-water, by dropping it into the eyes ; or to inftil into the eyes what is fqueezed from the pulp and . {kins throat, eyes, Sc. 161 fkins‘of the four pomegranate, firft chewed. Then wafh the eye-lids with a collyrium, made of the water of quinces, the juice of unripe grapes, boxthorn, aloe, and acacia: of each of thefe let there be one part, and a tenth part of faffron; and drop fome of it into the eyes. Bur if you obferve a turgefcence in the humors, and the eruption to be very copious, fo that puftules will certainly fall upon the eyes, becaufe rednefs appears here and there in their white part, from the excefs of the inflammation ; and alfo find, that what you have applied does not re- move that rednefs, but only leffen it fora time; after which it returns more violently than before, or at leaft continues as it was, when you began this treatment; you muft not proceed any longer in this me- thod, but, inftead of thefe things, Z drop 162 Of taking care of the drop into the eyes fome of the acid liquor expreffed from mouldy bread, with the Vabathean bitter, in which there is no vinegar, or other acid. As to the puftules, which break out in the tunica cornea of the eye, thefe darken the fight, and are to be cured, according to the degree of their thicknefs, by fuch diffolv- ing remedies, as I am going to de- {cribe : which indeed are fometimes effectual, and fometimes not; the fuccefs depending upon the matter being more or'lefs thick, and upon the greater or lefs firmnefs and dry- nefs of the body. But if large puftules fhew them- {elves in the tunica uvea, ule the collyrium of rofe-water feveral times in the day and night, with great di- lizence; or elfe that before-men- tioned, leaving out the faffron ; in- ftead of which, put a {mall quan- tity throat, eyes, &e. 163 tity of blood-ftone, to keep down the fwelling. Tuzse things are what ought to be known concerning the eyes. Care is next to be taken of the throat and mouth, left any eruption there fhould grieve the patient, and hinder his breathing ; for it often happens, that in a bad kind of the difeafe, terrible fuffocations are brought on, which leave no hopes of a recovery. Tuererore, on the firft ap- pearance of the figns of the {mall pox, let the mouth be gargled with the water of acid pomegra- nates, or of fumac, or with the juice of mulberries, or with fome of thofe things, which we have recom- mended, (chap. V.) under the head of extinguent remedies ; or laftly, if nothing elfe be ready at hand, with pure cold water; and that very often, to prevent a great eruption eS into 164 Of taking care of the imto the throat and mouth, and ftrengthen thofe parts, or at leaft hinder what is already broker. out there from caufing a fuffocation. Be quick therefore, and diligent in ap- plying this cure, efpecially, if from a hoarfenefs of voice, ftreightnefs in breathing, and a pain in the throat, a neceflity of it fhall appear, Moreover, if the ftrength will bear it, take away blood from the cephalic vein; and that even after the whole eruption is over. And if the patient find any thing in his mouth, or throat, which hurts him ; and yet there is not too great < heat there, neither are his bowel: too loofe, let him lick by degrees of freth butter mixed with white fugar-can- dy. But if there be any heat and inflammation there, give a linétus of this kind. TAKE throat, eyes, &ec. 165 Take of fweet almonds decor- ticated one part; of the feeds of gourd two parts ; of white-fugar- candy three parts; the mucilages of the feeds of flea wort, and of laurel- berries ; a linus of gum-arabic, almonds peeled, and the feeds of the plane-tree, and wheat-flower : mix all thefe with a mucilage of quince- feeds. In the next place, let us take care of the limbs : for upon thefe a num- ber of very bad puftules often. arife, whieh corrupt them to fucha de- gree, that the mufcles, tendons, nerves, and the bones themfelves lie bare. Aflift therefore immedi- ately, if you obferve the figns of the difeafe to be violent and exceflive; that is, bathe the limbs with fan- ders, quince-water, Armenian bole, rofes, camphire, vinegar, and rofe- water: but take care not to overdo it. If the puftules are very large, open, 166 Of taking care of the open them with an incifion-knife, to let out the matter: and delay not this operation ; for the cafe is dan- gerous. Now let us come to the cure of the nofe and ears, left they fhould be over-filled with the pimples : for this will greatly afflia@ the patient; and when they break out in the inter- nal part of the ear, there is danger of their coming prefently into the nofe. Take therefore a cotton cloth, upon which camphire has been bro- ken ; by the help of this, put into the ear fragrant wine-vinegar, to which has been added quince-wa- ter, or the juice of boxthorn. Do this in the morning, and repeat it twice or thrice a day. - Last y, if a great pain arifes in the foles of the feet, prepare inftant- ly to anoint them with warm oil, and foment them with warm wa- ter throat, eyes, &Fc. 167 ter and cotton. If this does not af- {wage the pain, nor facilitate the e- ruption, beat up decorticated fefam with milk; anoint with it, and bind it on with cloths, and leave it upon the age all night. In the morning, put the foot into warm water ; ang repeat the fame again. Or etait dates with butter, and ap- ply them; or, laftly, anoint with the lees a the fefamine-oil. For, thefe, and the like things, foften and relax the fkin; and by this means diminifh the pain, and promote the eruption. 368 Of ripening etintok * IT WOK EDs K HeMM es OOK EO oek Wooo AGOw CHAP. VIII. Of ripening the {mall pox. HEN, after the eruption 1s W completed, you obferve the puftules tend too flowly to maturi- ty, and yet that the patient is other- wife in a very good way, as to his refpiration and pulfe, and pretty free from inquietude and anxiety ; then it behoves you, to affift the maturation of the puftules. Bur if, together with a back- wardnefs of ripening after the eru- ption, you perceive the puftules to become hard and warty, and the pa- tient not at all better ; or if his ill- nefs increafes; then you are to know that the {mall pox is mortal. Where- fore, have no thoughts of ripening the the fall pox. 169 the puftules ; for they are of that kind which cannot be ripened. Now, the maturation of the {mall pox, if curable, is to be effected by fomenting the body with the fteam of a hot decoétion in water of ca- momile, violets, melilot, marfh- mallows, and bran, either feparate, or collected together in two bafons; as we have directed above, where we treated of facilitating the eru- ption. Anp if then the patient feems te find relief and refrefhment by the fomentation, you are to abftain from thofe fumigations, which are commonly employed for drying up the puftules; until they ripen of themfelves, and are capable of bear- ing thofe things, which contribute towards drying them up: of which. we are now going to treat. Aa CHAP. 170 Of drying the puftules. SOOO OIC OOOK IOI OIOK $e SERIES SEER IIHR KISHORE ed § Ga gt hae Of drying the puftules. F the puftules are large and very numerous, they muft be dried ; or the fluid contained in them muft be foaked up with fine clean cotton, in which there is nothing that may hurt the patient. And then let fu- migations be made with the leaves of dried rofes, or with the leaves of the ftorax-tree, or with fanders, or with the leaves of the ivzs, or the tama- rifk : and indeed rofes are more con- venient in fummer, but tamarifks in winter. ‘Fue {mall ‘e fometimes abounds with too much moifture. When that happens, order the patient to lie on pounded rofes, or on rice-meal, or on Of drying the puftules. 27% on millet-meal, with which a mat- trafs of a thin texture is fluffed. Ir the body be full of puftules, lay moift leaves of the iv7s under the patient ; and befprinkle him with an aromatic powder, made of aloe, frankincenfe, farcocol, and dragon’s blood. Bur if the puftules break {ponta- neoufly, or from the quantity of the fluid contained in them, and are flow in drying, treat them in this manner. Taxe of fefamine-oil one ounce ; of Andarene(r1) falt pounded fine, and of alum, each two drachms. With this liniment anoint the body, care- fully avoiding thofe- places, which are ulcerated or excoriated, or even too near an approach to them; _be- (1) Andar isa village, | white foffil falt is found. a mile diftant from 4- | See Maundreil’s jour- leppo, where a very | ney. Aa2 caufe 172 Of drying the pufiules. caufe the medicine would raife a vio- lent inflammation. Let the. lini- ment lie on the parts for the fpace of an hour; then wath it off with a decoction in water of emblic my- robalans, white tamarifk - berries, myrtle - leaves, and pomegranate peels. Ir the puftules are dried by thefe means, it is well; if not, take the whiteft fort of bole (not the red bole)* add to it of Andarene falt, and of dry bread crumbled fine, each a tenth part. Make a liniment, with which rub the fkin; let it lie on for an hour or two, and then wath it off. Now we are to treat of taking off the dried fcales, and crufts, or efchars. CHAP. Of taking away the dry fcabs and efcars. W HEN the {mall pox is wi- thered, and the dry fcales and efchars {till remain on the fkin, exa- mine them well; and to thofe that are {mall and thoroughly dried up, apply warm fefamine oil every now and then, till they are foftened, and fall off: but thofe of the face are to be managed with oil of piftaches. For the larger fort, which refemble efchars, if you find any moifture remaining in them, cut them off carefully, without any application of oil. And if the places, from whence you have removed the ef- chars, contain but little moifture, it is to be dried up with foft cotton, as 174 Of iaking away &e. as I have already faid: but if they contain much, they are to be dried gradually ; befprinkling them with the red aroriatic powder, compofed of aloe, frankincenfe, farcocol, and dragon’s blood, efpecially if they begin to leffen, and fink in; and with alum and Andarene falt) if they are even with the reft of the furface of the body, and do not fink in: then wait till a new ef- char or {cab is formed on them. If there be any return of moifture, re- peat the fame dreflings. And in fine, when the moifture is entirely exhaufted, then anoint the parts with oil, until the crufts are foftened, and all fallen off. Next follows a difcourfe on de- ftroying the marks of the {mall pox, CHAP. Of defiroying the marks Bc. 75 OOO 7 OG OG GEE As Pei X: Of defroying the marks of the Small pox. ap marks of the fmall pox are of two forts: for they are either in the eye, or on the reft of the body. Now with ref{pect to the eye, the part on which the {mall pox broke out, has an opaque white- nefs in it, as we have already ob- ferved. If this happens in the eyes of children, or young perfons of a moift conftitution of body, and ten- der fkin, it will be the more eafily deterged. Now the medicines, which de- terge the eye, and take off the white- nefs, are thefe: borax, or. nitre made into cakes, Andarene falt, fal- ammo- 176 Of deftroying the marks ammoniac, glafs, the {cori of glafs, coral, tutty, lapis hematites, verdi- greafe; baftard fponge, the fea crab, the dungs or excrements of fparrows, fwallows, ftarlings, mice, bats, and of the Arabian or Lybian lizard; mufk, the fediment of urine; the acorus, ebony, cornel-water, A- rabian fugar, dregs of vinegar burnt, myrrh, fandaracha or juniper gum, commonly called varnifh, gums-of the olive and bitter almond-trees, and the milky juice of wild lettuce. It will be beft to ufe thefe, when the patient is juft come out of the bath, or after holding his head over the {team of hot water. But mild me- dicines alone, nay the mildeft of thefe, are to be employed, efpeci- ally in foft and moift bodies. T ue defcription of a mild me- dicine, which removes the white fpecks from the eye. Ler Let the eye be fprinkled with farcocol, and white fugar-candy. ANOTHER more efficacious. Ler the eye be fprinkled with baftard {ponge; farcocol, and fugar. Anoruer ftill more powerful. Take of verdigreafe ten drachms ; myrrh, fagapenum, {fal ammoniac, farcocol, of each two drachms and half ; baftard fponge, fcorie of glafs, and borax, or nitre in cakes, of each three drachms. Then take of {weet cane ten drachms, and the fame quantity of cornel-water. Boil thefe in ten times the weight of water, till the decoétion becomes thick : then diffolve the gums in it, and mix all well together into an ophthalmic collyrium. Afterwards, as occafion fhall require, to this mixture add ebony in an oil-bottle. Cleanfe the part affected gently and often with a needle or ftyle; taking Bb care of the mall pox. 177 178 Of defroying the marks eare to apply the collyrium frequent- ly, both before and after the opera- tion. And laftly, fprinkle it with the powder of the milder fort of the medicines. But be fure to look carefully into the eye every day. For if it be pained, or look angry, omit this treatment for fome days, and then repeat it ; for this method of cure is very powerful and effica- Cc1oUus. As to the medicines, which take off the marks of the fmall pox from the face and the reft of the body, they are thefe: white litharge, dri- ed reed- roots, rotten bones pow- dered, baftard fponge, coral, farco- col, almonds, birthwort, the ben nut, radifh-feed, pumpion - feed, rocket - feed, the flower of beans, rice, lupins, and kidney-beans. On thefe pour the agya amurce, and barley-water. Tue defcription of a liniment, which of the fmall pox. 179 which effaces the marks of the {mall pox. Take of the flower of chiche: and beans, each three drachms; of pum- pion-feed five drachms; of white li- tharge two drachms ; of dried reed roots three drachms. Pound all to- gether in barley-water : then apply it to the parts feveral times fuccef= fively, after the patient has received the fteam of hot water, or after coming out of the bath. Then again wafh him in a bath, made of pumpion-rinds, dried violets, bran, and pounded chiches, boiled in water : rub him well, and apply the liniment a fecond. time. Tue defcription of another lini- ment of greater efficacy. Take of bean-meal five drachms ; bitter almonds, fweet coftus, rocket- feed and radifh-feed, of each two Bb 2 drachms 180 Of deftroying the marks drachms and half: apply it, as we have already directed. Anortuer liniment more effica- cious ftll. Taxes of bitter almonds peeled five drachms; radifh-feed, rocket- feed, roots of coftus, and long birth- wort, of éach two drachms and half; of borax, or nitre made into cakes, three drachms ; of pepper one drachm and half: ufethem, as we have already directed. Afterwards, wath the parts with radifh-water, or with thofe things, which we have ordered. And thofe are the medi- cines, which efface the marks and {cars of the {mall pox. Bur in order to efface the pock- holes and render them even with the reft of the furface of the body, do thus: let the body be anointed with butter, and well tinged with the herb cyperis, or with its pow- | der : of the mall pox. 181 der: let the patient ufe the bath frequently, and be rubbed down af- ceric. Now we are to dire what ought to be given toa patient in the {mall pox by way of aliment, and to treat of the medicines which haye rela- tion to it. 182 Of the diet of patients Cl. ats als ia 4 allenic lsd’ SE ee Re ate aie ee lle ae Git AY... AU, Of the diet of patients in the fmall pox. be ty a patient in the {mall pox it is neceffary to give barley-water, prepared in the fame manner, and with the fame art, as that, which is ufually given to perfons in acute and hot difeafes. If the fever be moderate, and the body fomewhat coftive, it muft be fweetened with white fugat-candy ; but if the heat of the fever be intenfe, and the bo- dy loofe, pour to it half a meafure of the juice of acid pomegranates, pounded with their feeds: but the pulps and inward thin tunicles are to be avoided ; for they are laxative. Ir the patient be reftlefs, and cannot in the {mall pox. 183 cannot fleep, add to the barley-wa- ter fome proportion of poppy. But if the body be very loofe, add to the barley-water one part of dry feeds of acid pomegranates, and one part of se 9 i de Bur, if it be requifite to bind the body, inftead of barley-water, take meal of peeled barley, and the meal of pomegranate-feeds; boil thefe in the fame manner as barley-water is made, and let the fick drink of this, as he would drink of barley-water ; either alone, or with Bambu-fugar and gum Arabic mixed with it, if a loofenefs fhould make it neceffary ; er with the medicines which I fhall defcribe anon. For barley-water, mixed with pomegranate-juice, is very fervieeable in the fmall pox, and more efpecially in the meafles. But the waters of the gourd, of the Indian pumpion, and of the — er; 184 Of the diet of patients ber; the mucilage of fleawort-feeds, and the like, of whateverkind, which make a mild phlegm, and. eafy to be fpit up ;. thefe waters, I fay, are more ufeful in the meafles, than in the {mall pox ; unlefs it be in thofe forts of the fmall pox, which are accompanied with a malignity and heat, together with a violent fever and want of fleep. But in thofe cafes of the fmall pox, wherein the fever and inflam- mation are not fo vehement, thofe things above mentioned, and. others of the like kind, have no other ef- fe&, but to render them flower, and to protract the whole courfe of the difeafe: wherefore it will be your bufinefs to have recourfe to this or that fort of medicines, or to abftain from them, as occafion fhall require. For when the {mall pox happens to be in the higheft degree of heat in the fmall pox. 185 heat and putrefaction, with the ad- dition of moifture; then thofe things, which have a cooling, dry- ing and condenfing quality, are more proper; fuch as juice of pome- granates, verjuice, and others of the fame nature. Bur when the difeafe is the mea- fles, which arife from a vehement ebullition of the bile blended with the blood; thofe things, which have the twofold virtue of cooling and humeéting, are the moft proper in their cure; inafmuch as the cor- tupted blood is tempered and cor- rected by their means. For the blood of a perfon, in the meafles, is like ftagnating water, which putre- fies by long ftanding ; whereby its natural texture is deftroyed, and, by the action of the fun, it contraés a vicious acrimony. But if thefe waters are mixed with rain or any Cec ether 186 Of the diet of patients other running {weet water; they {oon recover their former whole- fomeneds. Moreover, in the fmall pox barley-gruel is beneficial, if it be taken with fugar and pomegranate- juice, or with a proper quantity of julap; giving due attention to the patient’s loofe or coftive {tate, as likewife to his greater or leffer de- grec of heat : except that barley-wa- ter is lighter to take, eafier to fwal- low, and more fuitable to the throat and breaft. Wherefore, a&t accord- ing to thefe directions, after you have been apprized, that barley-wa- ter is more proper for perfons in the meafles, than in the {mall pox; unlefs the fmall’ pox happen to be of a bad fort, in the manner we have mentioned. Asto the reft, vetchcs well cleanfed are good in the {mall pox, if a food be in the fmall pox. 183 be prepared of them with the juice of acid pomegranates, or with vine- gar: the meal of lentils is ufeful al- fo, if the meal be wrought up with cold water. Know likewife, that cold water is more ferviceable to a patient in the meafles, than in the {mall pox; as being fafer, and of a more cer- tain effect. | Now, when you fee the {mall pox attended with great infamma- tion, and a ftoppage in the pulfe and refpiration; then give extin- suifhing medicines, proportioned to the fymptoms: if they are lefs ur- gent, employ few; if very urgent, employ many. Bur never allow the eating of young birds, untill the pulfe and breath have returned to their na- tural ftate; nor till the puftules are Cc2 tho- 188 Of the diet of patients &ec. thoroughly withered, and the {cabs fallen off. Let us now turn the difcourfe upon loofening the belly, and re- > ftringing the fare 3 in the {mall pox. tL, shy Nites oF can ~ ty ") $A x 2 CHAP; Of managing the 8c. 189 “Bae HA SRO HOR, RH HE ye HM Rene amt Reale wee glee, CG bP AgiP.: - XI. Of managing the difcharges of the belly in the Small pox. T HE belly.is generally loofe in the fmal] pox and meafles to- wards their decline, but efpecially in the meafles. For which reafon, every thing muft be avoided which opens the body, after the fmall pox and meafles are condudted to the end ; even though the body be bound. But if it be lax, inftantly abftain carefully from thofe things, which give ftools: altho’ it be ne- ceflary in the beginning of thefe two difeafes, and before they are on the decline, to give a laxative. For it is fometimes requifite to open the body in the fmall pox, either upon account of the excefs of heat, and pain 190. Of managing the difcharges pain in the head ; or in order to eafle nature of her load, and leffen the morbific matter, when you have reafon to think it over-abundant. And it will be really fo, when you find the body, both before and after bleeding, neither weakened nor waft- ed; but, on the contrary, bloated and full, with a palenefs, or a little rednefs, and a fluctuating pulfe. For fometimes, in fuch a ftate, bleed- ing will not be neceflary, and it will be fufficient to evacuate the fuper- fluous humidity : and that efpeci- ally, when the aforefaid figns evi- dently appear; and befides, if through the fluggifhnefs of the fe- ver, the body be dejeéted, and en- tirely void of a red colour. In this ftate, a very proper medicine is a Jecoétion of yellow myrobalans, if it be drank with white hard fugar, and the juice of an acid pomegra- nate, (two or three, if there be oc- cafion) in the fmall pox. IOI cafion) bruifed with the pulp and internal tunicles. For it is the qua- lity of thefe two medicines to purge the body of the fuperfluous humors, together with part of the bile, with- out raifing any heat ; efpecially the pomegranate juice; and to leave nothing behind them in the inte- ftines. And this is the beft medi- cine, which can be given in this cafe. Bur in the meafles give the juice of Damafcene plumbs,and the plumbs themfelves, frefh - gathered, either alone, or bruifed with julap, ad- ding fugar tothem, But avoid the medicine called Zarangioben(1): for it is as prejudicial in the meafles, as honey is in the {mall pox; both upon account of the exceflive heat, (1)°A fort of Manna | on the leaves of certain among the Sogdians, | fhrubs, and is gather- Medes, and Babyloni- | ed thence. ans, which concretes | which 192 Of managing the difcharges which it occafions, and of increaf- ing the naufeating and uneafinefs éf the fick, .; In like manner, care- By avoid giving them the juice of ivy, or of the black violet to drink : kecawi they both equally heighten the diforder in the body. N ow, whereas the firft and moft neceflary remedy in the {mall pox x, to draw blood, when it is too much in quantity, or there is no profpect of checking its ebullition by any other means, even by ex- tinguents; but hele is a neceflity for taking a little away, as well for relieving nature, as for abating the fulnefs of the blood -veflels, and eafing them of their over-great load, which muft otherwife be productive of very bad confequences; efpecially if the blood be heated to that degree, that 2 violent inflammation might enfue: in the fame manner, it behoves you, in in thé {mall pox. 193 in the beginning of the meafles, to draw off fome of the bile, when you perceive it over-abundant ; and then to purfue what remains of it by extinguents. Now the fign of an exceflive redundancy of the bile is, the violence of the inflammation, and the uneafinefs, together with the difcharge of the fame bile, both by vomit and ftool, and a bitternefs in the mouth. Bur if the quantity of the bile is not exceflive, and yet there is an uneafinefs, and thirft, and vehe- ment heat, without any appearance of bile, either by vomit or ftool; though its quantity, I fay, be'not exceflive, we may however judge it to be of a bad quality, in proportion to the violence of the inflammation and uneafinefs. Anp this is what I have thought proper, that you fhould know, con- Dd cerning 194 Of managing the difcharges cerning the management of the dif- charges of the belly, when it is loofe in the beginning of thefe two dif- tempers. Now, if the belly: be lax, give nothing laxative: for in this cafe, any thing that increafes the difchargesis not fafe in either of the diftempers. But while the belly con~ tinues loofe, order the patient, in- ftead of barley-water,to drink barley- gruel; and if it be neceflary, boil the barley-gruel with meal of pome- ranate-feeds; of which let him. drink, before he returns to the ufe of barley-water. And if, this not- withftanding, the loofenefs ftill in- creafes, mix gum-Arabic and Bam- bu-fugar in. his drink in this man- ner. T axe of gum-Arabic two drachms; of Bambu-fugar one drachm: re~ duce them to. the confiftence of a collyrium: then on four ounces of the in the {mall pox. 195 the barley-gruel pour fome of the medicine, which I am going to de- {cribe; let it ftand for an hour, and give it to the’patient to drink. Tue defcription of the medicine, T axe of red rofes ground fine, Bambu-fugar, forrel - feed, fumac, and berberies, of each equal parts ; alfo gum-Arabic, fealed earth, pop- py-tinds, balauftines, or pomegra- nate-flowers, of each half the quan- tity: let the patient drink three drachms of thefe, with one ounce of the juice of acid pomegranates. But, if the loofenefs ftill conti- nues, and has weakened the patient, give him draughts of 4/-raib, that is, four fkimmed milk, with the beft fort of bifcuit, and a littl gum-A-~ rabic. Finatty, whenever a dyfentery appears, the method of cure muft d2 be SSS eae 196 Of managing the &c. be taken from the place, where we have treated of that fubje@. ™ N ow it remains, that we fpeak of thofe, who recover, and of thofe, who die of the {mall pox and meafles. CHAP, Of the curable &c. 197 EVEL AH NOVA SEH S Eee SESS EE EET FE A: Ps KTV. Of the curable and incurable fmall pox and meafles. H E {mall pox and meafles are of the number of hot difeafes, and therefore have many things in common with them. Now the chief prognoftic figns in thofe, who re- cover, are, a freedom of refpiration, a thorough foundnefs of mind, and an appetite for food; an agility to motion ; a right ftate of the pulfe ; the patient’s good opinion of his dif- eafe; a convenient pofture in bed ; and but little toffing about and in- quietude of body. Hence a judgment may be formed of bad figns, the greateft part 198 Of the curable and art of which we have related in the ‘book, intituled 4/-man/ori (1). Turse things following parti- cularly regard the {mall pox and ‘meafles. Wuen the puftules of the fmall pox are white, large, feparate, few yn number, eafy and fpeedy in com- ing out, and the fever not violent or burning, nor attended with much inquietude of body or concern of mind; and are fo qualified, that the heat, concern, and inquietude diminifh upon their eruption, and entirely ceafe, when the eruption is completed: that fort is curable, and threatens little or no danger. To thefe the next in goodnefs are, white large puftules, though very numerous and coherent; if they come out eafily, and their total e- (1) There is a MS. co- | Bodleian library, Nar- py of this book in the | cif. Marfh, N°. 376. ruption incurable {mall pox, &e. 199g ruption eafes the patient of his un- eafinefs and exceflive: heat, as. we have already mentioned. Burr when their eruption is per- formed: with difficulty, and the pa- tient does not grow better upon their coming out, they area bad fort: ‘although there is not fo much reafon to be afraid, if he fhould be ill while they are coming out, as if he: continues fo after the: eruption. Bur there is § bad, and: even & fatal fort of white large puftules, to wit, thofe which run together, and fpread. fo that many of them unite, and occupy large {paces of the body 5: or become like broad circles, and in: colour refemble fat. As to thofe puftules, which. are white, very {mall, coalefcing, hard, warty, and contain no fluid ; they are of a bad kind: and their bad- nefs 200 Of the curable and nefs is in proportion to the degree of difficulty in their ripening, and to the continuance of the fymptoms on their eruption. But if the fym- ptoms are not abated, after the e- ruption is finifhed, it is a mortal fign, Tuose puftules alfo are all bad, which turn green, purple, or black. But if, befides, a {wooning and pal- pitation of the heart come on ; this is the worft fign of all, nay a fign of certain death. Anp when the fever increafes af- ter the eruption of the {mall pox, it is a bad fign. But if the fever ceafes at the time of the eruption, it is a good fign. Doubled puftules indi- cate a great quantity of the matter of the difeafe: and if they are of the curable kind, they portend. re- covery 3 incurable jmall pox, Fc. 20% covery ; but if of the mortal kind, death. THoses meafles are the fafeft which have not too much redne§ : but if they turn pale, it is a bad fign ; the green and purple forts are both mortal. When either the {mall pox or meafles fink in fuddenly, af- ter they began to fhoot out; and then the patient is feized with in- quietude and anxiety, and a {woon- ing comes on ; it is a fign of {peedy death ; _unlefs they pufh out again, after they have fubfided. Ir the puftules appear on the firft day of the fever, they will haften their progrefs, and be of quicker motion: if the eruption is protract~ ed to the third day, it will advance moderately ; but if the firft appear- ance pafles the fourth day, the eru- ption will be completed dully and flowly. Ee WHEN 202 Of the curable and W 1 £N the appearance begins on the good critical days, it isa falu- tary fign, efpecially if the patient Gnds himfelf better at the end of the eruption ; and fo on the con- trary. But when the puftules be- gin to'run into one another, and to {pread ; and at the fame time the jnquietude _increafes confiderably, and the belly fwells or is bloated ; then death is near at hand. When the fmaller fort of puftules, which contain no fluid, grow hard ; and a delirium comes on atthe fame time; the patient is near his end. When it happens that the {mall pox and meafles appear and difappear alternately, and are attended with anxiety anda delirium; this is a fign of death, of what colour foever the puftules are: but it is feldom the cafe of white puftules, or of thofe, which ripen quick. When to- wards the end of the {mall pox, there incurable {mall pox, Ge. 203 there is a great perturbation of the humors, and the patient is feized with avery violent pain in a leg, hand, or any other limb ; or the pu- ftules are fpeedily converted intoa green or red colour; and thereup- on he grows weaker than he was before, and the weaknefs ftill in- creafes by the quick returns of the pain, and the limb contraéts vari- ous colours ; thefe are figns of death, But if neverthelefs the patient grows ftronger, he will recover, and that limb will be cured. Now if you fcarify that limb the very moment, when the pain begins to feize it, you will render great fervice to the patient, if he grows ftronger after the incifion ; and the limb will alfo be preferved from mortification. Burt, in this dangerous cafe, no- thing cooling muft be applied to the 204 Of the curable, &c. the limb, upon any account what- foever: but either fcarify it, or plunge it into hot water, if you fee that the patient can bear it. WHEREFORE, as we have run over all the articles, which we pro- pofed to ourfelves ; and have am- ply enough treated, both of this difeafe, and the method of prefer- vation from it; we here break off the thread of our difcourfe. To the beflower of firength to finifh this work, be praife without end, as he is worthy of being celebrated and praifed. The END.