$.,k.sav . ‘%€..‘ . ‘ . \ ‘ 1 ‘ M .. . . . . . . . .. , . ».~w7 A.-.b‘_.¢w£w3.".\$.r)...L ?~ .. _‘ . , . 4 . ‘ Y _. . . I ¢..w1., ~ ;.-.-20 GM; *4. v , . ¢ ., V . . . ., . ,-.§»f, . mi . _~..~.,.I».!n: £.-m',..n .A.,..._. L S .1... . . . . ‘ . . cf. .£.~6.»Jus. J..§IA.¥\~.Q. .. . , . .. a z . r . .. . . . . . .. . .. . uswwmfiuqnxd .,..a...7...!..*..¢..?.\.:.5v . . R »..v:.;»w....“E>i.$A..{..,. . ‘ . . ‘. ‘ ‘ . ‘ V. . : . 1 ;. 5 .1 ‘ ,, . , 2.1 (.01. I . 0 p Y ‘ .~ Q . ‘ » V . . , .,~ . _ . . > , . ‘ » . ‘ . ,. . . .. if ,. 0.1 ' J E- ‘. . ¢ 7 ‘ ,v . . “ .. , , .JVL»?v , ‘ Y. . . . 51%.. .3,w.\i3~1.|,..v&u.$..v.\.... Y ; w . . , ‘ Y . . , . .. ‘ . ‘ . ‘ |dr\|£\?.\t.‘..~‘\r+c.L£! :5. 2"»? .2! Wid. ....‘m‘,V .r;_.w»a.r,.;nw~.,.v4, .._3,.r.. ~... w .. ,1 \.:,,.Hl~.“ ,,‘?‘..vfi.‘.‘.,,.h.‘.‘ .M,~; .a. 1 ‘ u..11. . \\ “ 1: 5: , ‘ . 1 . . . . ‘ \ . “ “ Q) ‘ 1 fie ?_ 1:5 ~1 \ I {O Q E =.=:.__E.====..===__=:_===_=====_:=_=. = . -=:_.=:=:=i-:::.:=_ N ._ .:=F_=-2. " '..|....'.'.."..".-..'.....I"‘.-l‘. . \l-.'.>"|."‘ ..I‘..--..'.|". ."."'.' ..." H. . ._1.....m.n".‘_z.. 0 > II: A .7 4 . -5.; H \ A u. . w J . M w. . m .. W . w .. svqUAER|$'P£Ni N5LAM'AM A:/.\r/_\9Z.\|/‘\|v:\|1.\u.\I).\u m.\u.u1 su ..J._q_=_.=_.===2==§q@@._=£==#_§===.5_ *+é/£3 .fi3@® Jwéffi W 31 THERAPEUTICS ~._._ _- » A _ ¢w.. -- j)' J“ / I; I- OF Q , ,..._ .1..- v-‘._,_-AA -¢-_. NERVOUS DISEASES; INCLUDING ALSO THEIR DIAGNOSIS AND PATHOLOGY. BY CHARLES PORTER HART, M.D., LATE PROFESSOR OF DISEASES OF THE NERVOUS SYSTEM IN HAHNEMANN HOSPITAL COLLEGE, SAN FRANCISCO; HONORARY MEMBER OF THE COLLEGE OF PHYSICIANS AND SURGEONS OF MICHIGAN; MEMBER OF THE AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE; CORRESPONDING MEMBER OF THE CALIFORNIA STATE HOMcEOPA- THIC MEDICAL SOCIETY ; FORMERLY SURGEON-IN-CHARGE OF THE SURGI- CAL WARDS, CHIEF SURGEON TO THE EYE DEPARTMENT, AND PRESIDENT OF THE BOARD OF MEDICAL EXAMINERS, OF BROWN GENERAL HOSPITAL, U. S. A., LOUISVILLE, KY.; AUTHOR OF TREATISES ON “DISEASES OF THE NERVOUS SYSTEM,” “ INTRACRA- NIAL DISEASES,” “DISEASES OF THE SPINAL MARROW AND ITS COVERINCS,” ETC., ETC. PHILADELPHIA : F. E. BOEBIGKE, HAHNEMANN PUBLISHING HOUSE. 1889. Copyright, F. E. Boericlce, 1889. TO SAMUEL LILIENTHAL, M.D., PROFESSOR OF NERVOUS DISEASES IN THE HAHNEMANN HOSPITAL COLLEGE OF SAN FRANCISCO, THIS VOLUME IS RESPECTFULLY INSORIBED BY HIS FRIEND AND CO-WORKER, THE AUTHOR. I’ PREFACE WHEN the author of this work first published his Treatise on Diseases of the Nervous System, our practical knowledge of the therapeutics of nervous diseases was, if not in its infancy, at least far behind what it is to-day. Not only was our clinical experience in many of these affections exceedingly scanty, but as to some of their forms was entirely wanting. Not only SO, but much of what was recorded was wholly unreliable, and therefore worthless. It was unreliable, because many diseases of the nervous system which are now known to depend on. organic alterations of nerve tissue were then believed to be purely functional, and the temporary ameliorations incident to their course were frequently supposed to be the effects of medical treatment. But now, it may be truthfully aflirmed, our knowledge of the pathology and therapeutics of nervous diseases will compare favorably with that of any other class of disorders. The improvement is mainly due to the fact that in most of our colleges competent professors of nervous diseases have for years been constantly and earnestly engaged, not only in imparting a knowledge of these diseases to medical students ——-among whom are included the majority of our present practitioners—but in clinical investigations, based upon the homoeopathic law, many of which have resulted in important therapeutic discoveries. The consequence is, but few definite lesions of the nervous system remain unprovided with remedies possessing welI—recognized and clearly defined characteristic properties homoeopathic thereto, while the therapeutic effects of those previously employed are now, as a rule, better under- stood and more specifically determined. In short, it ispgratify- ing to know that we are at present in the full tide of success as regards the study and scientific treatment of this important class of diseases. 4 PREFACE. No apology, therefore, would seem to be needed for the appearance of the present work. On the contrary, the time has arrived when, in the author’s opinion, such a Manual of Nervous Therapeutics as is here presented is demanded in the interests of our School. As the chief excellence of a work of this kind is reliability, the author has been careful to make use of only such material, out of the large amount available for the purpose, as he could safely and fully indorse. Hence, comparatively few of the more recently introduced remedies have been admitted, except under the head of auxiliary treatment. This is especially true as regards those occasionally employed in the treatment of the more common nervous disorders, such as neuralgia, convul- sions, etc., for the successful management of which we already have an abundance of well-tried remedies. In excluding a number of the more recent, irregular and unproved remedies, the author is conscious of the fact that he has no doubt omitted some which have proved curative in particular cases. But it is a relief to him to know that deficiencies of this sort are quite unavoidable. As Grauvogl has well remarked: “It is impos- sible to prepare a complete special Therapia for any so-called disease.” In other respects, also, the work doubtless has its imperfections, as, indeed, every such work must have, since there is yet a great deal to learn regarding the nature and treatment of nervous and mental diseases. The importance, however, of having what we do know concisely set forth will, the author trusts, be regarded as a sufiicient excuse, if any were needed, for adding another supplementary volume to his series of works on diseases of the nervous system. In conclusion he would remark, that his chief aim has been to furnish a handy, practical guide to the successful treatment of every form of nervous disease, by presenting in one small volume the diagnosis, pathology and therapeutics of one of the most interesting, important and progressive departments of medicine. .CHARLEs Ponrnn HART. Wyoming, 0., Sept, 1889. CONTENTS. PART I. DISEASES OF THE BRAIN AND ITS MEMBRANES. PAGE Cerebral anaemia . . . . . . . . . ; . . . . . . . . . . . . . . . . 9 Cerebral hyperaemia . . . . . . . . . . . . . . . . . . . . . . . . . 14 Cerebral haemorrhage . . . . . . . . . . . . . . . . . . . . . . . . 21 Cerebral thrombosis . . . . . . . . . . . . . . . . . . . . . . . . . 27 Cerebral embolism . . . . . . . . . . . . . . . . . . . . . . . . . . 30 Encephalitis . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32 Cerebral softening . . . . . . , . . . . . . . . . . . . . . . . . . . 34 Aphasia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37 Cerebral hypertrophy . . . . . . . . . . . . . . . . . . . . . . . . 39 Cerebral atrophy . . . . . . . . . . . . . . . . . . . . . . . . . . 40 Multiple cerebral sclerosis . . . . . . . ' ' ' . . . . . . . . . . . . 42 Athetosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 44 Cerebral syphilis . . . . . . . . . .‘ . . . . . . . . . . . . . . . . 45 Cerebral tumors . . . . . . . . . . . . . . . . . . . . . . . . . . . 48 Cerebral concussion . . . . . . . . . . . . ' ' ' . . . . . . . . . 50 Sunstroke . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 52 Cerebral paralysis . . . . . . . . . . . . . . . . . . . . . . . . . . 54 Infantilecerebralparalysis. . . . . . . . . . . . . . . . . . . . . . 56 External cerebral pachymeningitis . . . . . . . . . . . . . . . . . . 58 Internal cerebral pachymeningitis . . . . . . . . . . . . . . . . . . . 59 Cerebral arachnitis . . . . . . . . . . . . . . . . . . . . . . . . . 60 Traumatic cerebral leptomeningitis . . . . . . ‘. . . . . . . . . . . . 61 Simple acute cerebral meningitis . . . . . . . . . . . . . . . . . . . 62 Tubercular cerebral meningitis . . . . . . . . . . . . . . . . . . . 67 Chronic cerebral meningitis . . . . . . . . . . . . . . . . . . . . . 71 Chronic hydrocephalus . . . . . . . . . . . . . . . . . . . . . . . . 73 6 CONTENTS. I PART II. DISEASES OF THE SPINAL MARROW AND ITS MEMBRANES. PAGE Spinal hyperaemia . . . . . . . . . . . . . . . . . . . . . . . . . . 76 Spinal anaemia . . . . . . . . . . . . . . . . . . . . . . . . . . . 78 Spinal irritation . . . . . . . . . . . . . . . . . . . . . . . . . . . 81 Spinal haeraorrhage . . . . . . . . . . . . . . . . . . . . . . . . . 84 Spinal meningitis . . . . . . . . . . . . . . . . . . . . . . . 85 Myelitis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 88 Myelomalacia . . . . . . . . . . . . . . . . . . . . . . . . . . . . 90 Spinal paralysis . . . . . . . . . . . . . . . . . . . . . . . . . . . 92 Acute ascending paralysis . . . . . . . . . . . . . . . . . . . . . . 94 Spinal paralysis of adults . . . . . . . . . . . ' . . . . . . . . . . . . 95 Infantile spinal paralysis . . . . . . . . . . . . . . . . . . . . . . . 97 Pseudo-hypertrophic spinal paralysis . . . . . . . . . . . . . . . . . 98 Glosso-labio-laryngeal paralysis . . . . . . . . . . . . . . . . . . . . 99 Progressive muscular atrophy . . . . . . . . . . . . . . . . . . . . . 101 Amyotrophic lateral sclerosis . . . . . . . . . . . . . . . . . . . . . 102 Multiple spinal sclerosis . . . . . . . . . . . . . . . . . . . . . . . 103 Primary spinal sclerosis . . . . . . . . . . . . . . . . . . . . . . . 104 Secondary spinal sclerosis . . . . . . . . . . . . . . . . . . . . . . . 106 Posterior spinal sclerosis . . . . . . . . . . . . . . . . . . . . . . . 107 Spinal tumors and other abnormal growths . .‘ .' . .' .' .' . .' . . . . . . 112 Spinal concussion . . . . . . . . . . . . . . . . . . . . . . . . . . 112 PART III. CEREBRO~SPINAL DISEASES. PAGE Cerebro-spinal hyperaemia . . . . . . . . . . . . . . . . . . . . . . 116 Neurasthenia . . . . . . . . . . . . . . . . . . . . . . . . . . . . 117 Cerebro-spinal meningitis . . . . . . . . . . . . . . . . . . . . . . 123 Infantile convulsions . . . . . . . . . . . . . . . . . . . . . . . . 129- Postnatal convulsions . . . . . . . . . . . . . . . . . . . . . . . . 133 Puerperal convulsions . . . . . . . . . . . _ . . . . . . . . . . . . 134 Toxaemic convulsions . . . . . . . . . . . . . . . . . . . . . . . . 138 Epilepsy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 139 Tetanus . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 144 Hydrophobia . . . . . . . . . . . . . . . . . . . . . . . . . . . . 148 Chorea . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 152 Hysteria . . . . . . . . . . . . . . . . . . . . . . . . . . . . 156 Hystero epilepsy . . . . . . . . . . . . . . . - . . . . . . . . . . 159 CONTENTS. 7 PAGE Catalepsy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 161 Multiple cerebro-spinal sclerosis . . . . . . . . . . . . . . . . . . . . 162 Secondary cerebro-spinal sclerosis . . . . . . . . . . . . . . . . . . . 162 General paralysis . . . . . . . . . . . . . . . . . . . . . . . . 163 Paralysis agitans . . . . . . . . . . . . . . . . . . . . . . . . . 164 PART IV. DISEASES OF THE PERIPHERAL NERVOUS’ SYSTEM. . ~ PACE Neuritis . . . . . . . . . . . . . . . . . . - _ . . . . . . . . . 166 N euralgia (in general) . . . . . . . . . . . . . . . . . . . . . . . . 167 Trigeminal neuralgia . . . . . . . . . . . . . . . . . . . . . . . 171 Mastodynia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 174 Coccygodynia . . . . . . . . . . . . . . . . . . . . . . . . . . . . 175 Sciatica . . . . . . . . . . . . . . . . . . . . . . . . . . . . . , . 177 Pharyngeal paralysis. . . . . . . . . . . . . . . . . . . . . . . 181 Paralytic aphonia . . . . . . ~. . . . . . . . . . . . . . . . . . . . . 181 Facial paralysis . . . . . . . . . . . . . . . . . . . . . . . . . . . 183 Diphtheritic paralysis . . . . . . . . . . . . . . . . . . . . . . . . 185 Glossoplegia . . . . . . . . . . . . . . . . . . . . . . . . . . . . 186 Facial spasm . . . . . . . . . . . - . . . . . . . . . . . . . . . . . 187 Torticollis . . . . . . . . . . . . . . . . . . . . . . . . . . . . 187 Writer’s cramp . . . . . . . . . . . . . . . . . . . . . . . . . . . 188 Spasm of the glottis . . . . . . . . . . . . . . . . . . . . . . . . . 189 Facial atrophy . . . . . . . . . . . . . . . . . . . . . . . . . . . 191 Peripheral anaesthesia . . . . . . . . . . . . . . . . . . . . . . . . 192 PART V. I DISEASES OF THE SYMPATHETIC NERVOUS SYSTEM. PAGE Hemicrania . . . . . . . . . . . . . . . . .. 195 Exophthalmic goitre . . . . . . . . . . . . . . . . . . . . . . . . . 198 Myxoedema . . . . . . . . . . . . . . . . . ..199 Angina pectoris. . . . . . . . . . . . . . . . . . . . . . . . . . . 200 Gastralgia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 204 Ovaralgia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 208 Hysteralgia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 210 Enteralgia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 211 F 8 CONTENTS. PART VI. SYMPTOMATIC DISEASES. PAGE Cephalalgia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 214 Vertigo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 223 Coma somnolentum . . . . . - . . . . . . . . . . . . . . . . . . . 229 Insomnia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 232 PART VII. MENTAL DISEASES. PAGE Melancholia . . . . . . . . . . . . . . . . . . . . . . . . . . . . 237 Hypochondriasis . . . . . . . . . . . . . . . . . . . . . . . . . . 240 Moral insanity . . . . . . . . . . . . . . . . . . . . . . . . . . . . 241 Mania . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 243 Dipsomania . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 249 Mania 5 potu . . . . . . . . . . . . . . . . . . . . . . . . . . . . 250 Dementia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 252 THERAPEUTICS OF NERVOUS DISEASES. PART I. DISEASES OF THE BRAIN AND ITS MEMBRANES. CEREBRAL ANEMIA. Syn0nyms.—Brain-Fag, Cerebral Hypaemia, Cerebral Hy- paemia et Hydraemia, Cerebrasthenia, Neurasthenia Cerebralis; F02, Anemie Cérébrale; Ger, Anéimie des Gehirns, Gehirn-andmie. Definition.-—A condition in which the blood contained in the cerebral vessels is deficient in quantity or defective in -quality. Diagnosis.-—The history of the case is usually suflicient to establish the diagnosis. When, as is sometimes the case, the symptoms resemble those of cerebral hyperaemia, the condition may be recognized by the following comparison: Cerebral Anwmia. Cerebral I-Iyperaamia. I Patient anaemic, weak and pale. Patient plethoric, red face. Disposition to sleep. More or less insomnia. Pulse small and weak. Pulse full. N euralgic headache, chiefly limited to Cephalalgia of a dull, aching character, forehead and vertex. and diffused. Pupils dilated. Pupils contracted. Relieved by stimulants and horizontal Aggravated by stimulants and by lying position. down. Anaemic murmurs. No abnormal heart sounds. 2* (9) 10 NERVOUS THERAPEUTICS. Pathology.-——That the characteristic symptoms of cerebral anaemia are due, in most cases, to an insufficient supply of blood to the brain may be readily shown by diminishing the supply by compression of the carotid arteries, or by simply suppressing the breathing. When caused by an impoverished condition of the blood, the nutrition of the brain suffers through a deficiency of the red corpuscles, which are the car- riers of oxygen. In these cases the effects are similar to those resulting from a deficiency in quantity, the chief difference being that the symptoms are gradually instead of suddenly developed. Clinical Experience.——China, Ferram and Digitalis, aid ed by a blood-making diet, have generally proved successful where there was a deficiency of blood, the Digitalis being most useful in cases attended by feeble action of the heart. The oaso-motor form of cerebral anaemia generally yields promptly to Amyl 'n.it'r., Glonoin, Picric ac. and Am/m. brom. 3x. Chronic cases have been greatly benefited by New com. and Phosphorus. Ver- tigo generally yields to Ac. fluor, Baryta carb., Graph, Dycop. and Silicea. Hale has found Atropine2 “an admirable remedy in cases of advanced typhoid, when, with the general prostra- tion, there is insomnia, with incoherent mumbling, coma vigil and very dry tongue.” I have found Picric ac.6 well suited to this condition. Therapeutic Indications. —~Ghina. —-This remedy justly stands at the head of the list of remedies for anaemia, when caused by the excessive loss of animal fluids, as in haemor- rhage, diarrhoea, leucorrhoea, spermatorrhoea and overlactation. Its best effects are observed only after the drain upon the system has been arrested. The symptoms calling for it are: headache, especially in the morning ; ringing in the ears; pale, cold face; coldness of the extremities; great debility; tingling and trem- bling, or twitching, of the muscles and limbs; palpitation of the heart; faintness, which is relieved by lying down; insom- nia; vertigo, especially on raising the head. Arsenicum.-—This is a good blood-making remedy, and is best adapted to cases where the blood has become too watery, or depraved, as in malarial fever, chronic quininism and chlo- CEREBRAL ANEMIA. 11 rosis. It is also suited to cases aggravated by injudicious use of Ferrum. The indications are: great prostration, with rapid sinking of the vital forces; hammering headache; coldness of the extremities; restlessness; bloating of the hands, feet and face; thirst for small quantities of water; nausea; tendency to syn- cope on raising the head; vertigo, with vanishing of the senses; chilliness ; mental depression. Ferrum.—Cerebral anaemia dependent on hydraemia, as shown by great pallor of the face, lips and buccal mucous membrane; bellows-sound of the heart; muscles flabby and weak; beating headache; slight exertion produces shortness of breath and exhaustion. This remedy is generally best adapted to chlor- otic cases and to those resulting from passive haemorrhages. Avena sat.—Ooldness of different parts of the body, depend- ing upon want of nerve-force; brain-fag; nervous debility of school teachers and professional men; women who have be- come anaemic and debilitated by household cares, worry, over- nursing, etc. Nux vom.—Anaemia from mental exhaustion or overwork, as in students and professional people; also the anaemia re- sulting from debauchery and overstimulation, the long-con- tinued use of ardent spirits, late hours and high-seasoned food_ Especially indicated in all cases where there is gastric irrita- tion, indigestion or constipation; nausea and vomiting, with fre- quent eructations of sour-smelling fluids or food; insomnia; mus- cular twitchings; trembling of the hands; frequent cramps. OamphoI'.—Sync0pal form, resulting from the rapid loss of vital fluids, and causing great embarrassment of the respiration and circulation, spasms and convulsions; coldness of the body, vertigo and loss of consciousness. This is a transiently acting remedy, but very useful in meeting the primary symptoms, especially when caused by diarrhoea, cholera, etc. Ignatia.-—Cases occurring in weak, hysterical subjects, or in women who have become anaemic through grief or mental anxiety; melancholy, taciturn, nervous, seeks solitude, frequently gives way to tears; sinking sensation at the pit of the stomach; con- stipation; ooerlactation. Helonias.——Cases resulting from diseases of the female sexual 12 NERVOUS THERAPEUTICS. organs; menorrhagia; leucorrhoea, with general atony; pro- lapsus uteri; loss of sercual appetite; pains in the back from weakness and congestion; pulsatiie pains in the top of the head, increased by stooping, and attended by vertigo. Pulsatilla.-—Cerebral anaemia due to impoverishment of the blood, and associated with menstrual irregularity, especially in young girls approaching the period of adolescence; amenorrhoea, with vertigo, chilliness, peevishness, aching pain in the small of the back, beating headache, aggravated by stooping,-bloat ing of the face, hands and feet; hysterical cases, with pale face, disposition to faint and tremulous weakness. Gina.——Hydrocephaloid cases, with marked paleness of the face, especially around the nose and mouth ; transient dizziness, with double vision and obscuration; dilated pupils; spasms and convulsions; paresis; verminous irritation, producing irrita- tive fever. Ipecacuanha.-—Ansemia produced by the summer complaint in children, and attended with nausea, with or without vomit- ing, pale face, with blue margins around the eyes, coldness of the extremities; restlessness and sleeplessness, or else great drowsi- ness; convulsive movements of the limbs; stools frequent, emerald- green, faetid, and ejected with great force. Calcarea phos. — Chronic cases, caused by malnutrition; anaemic headache of school girls; weakly, anaemic children, with retarded development, especially of the teeth and osseous structures; hydrocephaloid cases. _ Zincum.——Well adapted to old chronic cases, especially when caused by the abuse of potassium bromide. Great mental and bodily depression; cold extremities; twitching of the muscles, with paralytic weakness; aching in the forehead after reading, rwriting or study; loss of memory; restlessness at night, with frightful dreams. Zincum phos., brom. and picr.-—The indications for the employ- ment of these remedies are: brain-fag of business men, teachers and professional men, who have become pale, haggard, weak and sleepless fro1n overwork, worry and prolonged mental exertion. Veratrum album.-—Acute cases caused by violent purging, at- CEREBRAL ANPEMIA. 13 tended with fainting, spasms and convulsions, and followed or accompanied by paralytic weakness. Secale c0r.—Anaemia complicated with diarrhoea or metror- rhagia, or with spasms and convulsions; small, intermitting pulse; tinnitus aurium; delirium ; loss of consciousness; numbness and coldness of the limbs. Natrum s11lph.— Watery condition of the blood; constant chilli- ness; hydrogenoid constitution; trembling of the body, with jerking of the limbs; great languor and prostration. Natrum mur.——Cerebral anaemia due to malarial poisoning; profound melancholy; circulation excited by every movement of the body; great weakness and constipation; pale, sallow com- plexion; effects of onanism. Sulphur. — Chronic cases, occurring in cold, phlegmatic, scrofulous constitutions; also when preceded or acdompanied by eruptions, or when caused by their suppression; also as an intercurrent remedy, or when indicated medicines fail to pro- duce any lasting benefit. Auxiliary Treatment.—When the anaemia is due to a sudden or copious loss of blood, its quality should be improved by such articles of diet as are not only easy of digestion; but rich in blood-making elements; such as beef, milk, eggs, game, fish, oysters, vegetables, etc. Only good food makes good blood; hence pies, pastry, rich cake and all unwholesome articles of diet should be strictly forbidden, and not permitted to displace a liberal allowance of good nutritious aliment. Fresh air and exercise are also of great importance, especially in chronic cases. An ocean voyage, exposure to the mountain or sea air, or even a complete change of climate, may be re- quired in order to fully restore the patient to health. In very bad cases, rest in the horizontal position, massage and electri- city may not only be found serviceable, but even indispensable. Salt-baths and sea-bathing are invigorating, and can generally be practiced with great benefit, provided proper precautions are taken at the commencement, and the exposure Inade to correspond at all times with the strength and susceptibility of the patient. 14: NERVOUS THERAPEUTICS. CEREBRAL HYPEREMIA. Syn0nyms.—Congestion of the Brain; Fr., Hyperémie Cére’- brale ; Ger, Hyperiimie des Gehirm, Gehirn-hyperéimie. Definition.—An increase in the quantity of blood within the cerebral vessels, causing a condition of congestion, undue pressure and more or less irritation. Diagnosis.-—Congestion of the brain should be carefully distinguished from cerebral anaemia, auditory and gastric ver- tigo, epilepsy, embolism and thrombosis of cerebral blood- vessels, softening of the brain and urinaemia, to all of which its symptoms bear more or less resemblance. The differential diagnosis between cerebral congestion and cerebral anaemia is given under the latter head, and need not be repeated here. Cerebral congestion differs from cerebral haemorrhage in the apoplectic symptoms being less pronounced. Thus, there are no stertorous breathing and no puffing of the lips; nor are consciousness, sensibility and the power of motion completely lost, as in cases of haemorrhage. Auditory and gastric vertigos are simply ear and stomach troubles, the former due to disease of the semicircular canals, and the latter to indigestion, which is always present at the time of the attack. In epilepsy an aura is often present, and this is generally followed by a peculiar cry; the patient falls suddenly, instead of slowly, to the ground, and the tongue is frequently bitten, none of which symptoms belong to cerebral congestion. In embolism the pulse and respiration are disturbed, being more or less irregular and rapid, owing to valvular disease of the heart, which is usually present; the heat of the head is not increased in this disease, there is no premonitory stage, and the symptoms are more permanent than they are in cases of cere- bral hyperaemia. In thrombosis, aphasic and paralytic symptoms are usually present from the beginning, and, notwithstanding occasional remissions, they gradually become more and more pronounced as the disease progresses. In cerebral softening the accession may be either gradual CEREBRAL HYPERZEMIA. 15 or sudden, but the paralysis is permanent and progressive, the speech is seriously impaired, the intellect is feeble and the disease fatal. Urinaemia may be distinguished from cerebral congestion by the evidence afforded by a chemical and microscopical ex- amination of the urine, by the anasarcous condition of the face and limbs, and by the frequent recurrence of convulsions and coma. Patho1ogy.—-The essential pathological element in cerebral hyperaemia is the congested state of the capillary vessels of the brain, and to this is due the functional disturbance or irrita- tion of that organ. The congestion is active when, owing to arterial dilatation, oxygenated blood passes rapidly through the cerebral capillaries; and passive, when, from venous Ob- struction, the capillaries contain mostly venous blood, which moves sluggishly through them. Clinical Experience. —— Aeonite, Glonoin, Belladonna and Hyoscyamus are generally prescribed in cases of acute active congestion, the last two being preferred when there is a marked tendency to delirium. Hale uses large doses (15 grs.) of Natr. brom. and Kali brom. in these cases, which he pronounces supe- rior to either Aconite or Belladonna. Opium and Apis have been given successfully in the apoplectic form, or when there was great cerebral depression. Gelsemium and Veratrum vir., both low, are usually given in cases of recent passive or venous hyperaemia, the latter being preferred when the blood pressure is very great, the face livid and the veins greatly distended. Nux vom. and Arnica are used in chronic cases, the former being prescribed for high livers and persons of sedentary life, and the latter in paralytic cases, or where there is a suspicion of thrombosis. Bryonia, Phosphorus, Salicylic ac. and Cuprum have also been given successfully in special cases. Therapeutic Indications.—Gl0noi11.—Acute active conges- tion of the brain, with strong beating of the carotid and temporal arteries, contracted pupils and very rapid pulse; throbbing headache, with flashes of light before the eyes; tin- nitus aurium; fulness in the forehead and vertex, with mental dul- ness; vertigo, with impaired vision; great restlessness and im- 16 NERVOUS THERAPEUTIOS. patience in mild cases; apoplectic and epileptiform cases, especially when caused by exposure to the sun’s heat or by menstrual suppression. Belladonna.—Acute cases attended by delirium or by spasms and convulsions; redness of the face and eyes; morbid vigil- ance; sensitiveness to light and noise; contraction of the pupils; stiflness of the tongue and neck; throbbing headache; great mental excitement; double vision; children start suddenly when falling asleep. Aconite.--Great restlessness and anxiety, with dry, burning skin and a full bounding pulse; throbbing in the head, with sense of fulness and heaviness; contracted pupils; vertigo, especially when stooping; heat, thirst and delirium; cardiac palpitation. This remedy is specially indicated when the attack is due to great emotional excitement or exposure to extreme heat. Hyoscyamus.——-Dark red face and sparkling eyes; violent de- lirium; lascivious mania; epileptiform attacks; muscular twitchings ; great nervousness; double vision; grating of the teeth. Acute attacks in which the nervous and mental phe- nomena predominate. Stram0I1ium.—This remedy is indicated in cases similar to those for which Hyoscyamus is recommended, the nervous ex- citement being extreme, and the delirium of the most active and furious character. The patient laughs, sings and gesticulates in rapid succession, or shows great fright, terror or rage. In milder cases, vertigo and temporary blindness are special indi- cations. Amyl nit.—Throbbing of the cerebral vessels, with sense of heat and fulness in the head; buzzing and throbbing in the ears; protrusion of the eyes, with flushing of the face; visible pulsations of the carotids ; violent cardiac action. At the very beginning of active cerebral hyperaemia. Bryonia.—-Painful outward pressure in the forehead and temples; active cerebral circulation, attended with bleeding of the nose; muscular twitchings during sleep; face red and puffed; gastric disturbances and constipation. Gelsemium.—-Dull, pressive and stupefying headache, extend- CEREBRAL HYPERZEMIA. 17 ing from os frontis to occiput; vertigo, dimness of vision and diplopia; drowsiness and mental confusion; dull, aching pain in the nape of the neck, with disposition to throw the head backward ; great muscular prostration; dropping of the upper eyelids. Most useful in the passive form of cerebral congestion, especially in malarial cases. Veratrum Vir.—Fulness and sense of weight in the head, with vertigo, confusion of mind and loss of memory; oppressed res- piration; labored action of the heart; tingling and numbness in the limbs. Passive congestions, especially such as result from alcoholic stimulants and malarial poisoning. Opium.—Apoplectic cases, with dark red and bloated face, slow pulse and diflicalt articulation ; great drowsiness, with confusion of mind, and sense of heaviness and pressure within the head; coldness of the hands and feet, with mumbling delirium. Suited to the passive and apoplectic forms, and also such as arise from fright or debauchery. Apis mel.——Sense of fulness and heaviness of the head, es- pecially in the occiput; burning and throbbing in the head, greatly aggravated by stooping; vertigo, with nausea; drowsi- ness, with inability to sleep, owing to extreme nervousness; redness and burning of the eyes and eyelids; sleep disturbed by oppressed breathing and unpleasant dreams. Most suitable in cases characterized by great cerebral depression. Nux vomica.—-Gastric derangement, with dulness and con- fusion of the head; sleeplessness during the latter part of the night; drowsiness, with a tendency to coma; symptoms ag- gravated by coffee, eating and exercise in the open air. Con- stipation, haemorrhoids and derangements of the stomach point to this remedy, especially in chronic cases caused by ex- cessive mental labor, sedentary modes of life, overstimulation by alcohol, the abuse of tobacco, worry and loss of sleep. Arnica.——Heat and burning in the head, with coldness of the rest of the body; throbbing in the forehead and temples, in- creased by stooping or exercise; tinnitus aurium; vertigo, at- tended with nausea, obscuration of sight or loss of conscious- ness; delirium. Chronic congestions, and also such as result from mechanical violence. l8 NERVOUS THERAPEUTICS. Phosphorus.——Heat and throbbing in the head, with vertigo, buzzing in the ears and heat in the vertex; lightning-like pains in the head; sense of weight in the forehead, increased by stooping. Chronic cases, and such as are due to mental strain or overwork. Cuprum.—Violent convulsive movements, either general or local; restless tossing about and constant uneasiness; pulse full, quick and strong; eyes red and inflamed, looks wild, and speech delirious; excessive thirst. Cases resulting from sup- pressed eruptions or retrocedent exanthemata. Gimicifuga.——Dull, heavy feeling in the head; pain in the temple and vertex, with a sensation of pressure; heat and ful- ness in the head, with throbbing and pressure; pain in and behind the eyes, also in the back of the head and neck; the brain feels too large for the skull; sensation as if the top of the head would fiy off; severe pain over the right eye. Cere- bral congestion, involving especially the base of the brain and complicated with spinal irritation. Aurum.—Heat and roaring in the head; scintillations before the eyes; extreme melancholy, desire for death and suicidal tendency; symptoms aggravated by mental exertion. Goifea.—Heat in the head and face, with flushing; bleeding of the nose; great nervousness and exaltation of the senses; hot head, red and glistening eyes and cold feet. Infantile cases occurring during the period of dentition, especially when associated with diarrhoea. ‘ Lachnanthes.—Dull headache, with sensation of upward press- ure in the vertex; vertigo, with feeling of heat and congestion in the chest; great outward pressure behind the eyes; burning sensation in the head, while the whole body feels cold; expan- sive feeling in the head, as if it was being split open. Rhus tox.—Burning, throbbing pains in the head, with sense of fulness; red and burning, or pale and puffy face; rvertigo when lying down; great restlessness, especially at night; waver- ing sensation in the brain; pains reappear after eating. Es- pecially adapted to cases caused by prolonged exposure to extreme cold, or by standing in cold water. Asclepias syr.—Headache, with vertigo, dulness and stu- CEREBRAL HYPERZEMIA. 19 pidity; sharp, stabbing pains, extending from one temple to the other; severe headache, with quick, full pulse and nausea; feeling of constriction across the forehead; scanty urine. This remedy is particularly indicated in cases where the perspira- tion has been suddenly suppressed. Pulsatilla.—Oppressive, beating headache, with confusion of mind; red and bloated face, with bright sparks before the eyes; vertigo, with tinnitus aurium; double vision, nausea and pal- lor of the face; bitter taste in the mouth; drowsiness during the day and sleeplessness at night; scanty or suppressed menses; symptoms worse in a warm room; ameliorated by pressure, or by going into the open air. Especially called for in cases caused by a sudden suppression of the menses, particularly in young girls. Sulphur.——Rush of blood to the head, producing redness and heat of the face, vertigo, and a sense of fulness and pressure within the cranium, with violent throbbing; pale face, with coldness of the extremities. As an intercurrent remedy in chronic cases. Auxiliary Treatment.-The removal of the cause is gen- erally the first thing to be considered, for whenever it can be effected it will greatly benefit the patient, and in many cases accomplish a cure. Where the exciting causes cannot be entirely removed, they may be lessened, and their injurious effects greatly palliated. Thus, the passive form requires rest, both physical and mental; hence all excess in eating and drinking, all excitement or gratification of the animal appe- tites and passions, in short, every form of bodily and mental exertion, should be studiously avoided. The active form re- quires similar restrictions, except that the injunction as to rest need not, as a rule, be insisted on to so great an extent. The patient, however, if able to be about, should abstain from all severe muscular exertions, especially in a stooping posture. But moderate exercise in these cases is often of great benefit. Dr. Kershaw relates several cases which were greatly benefited by regular and judiciously taken exercise, such as walking, riding, etc., carefully regulated according to the strength and health of the patient. 20 NERVOUS THERAPEUTICS. Professor Preyer, of Jena, claims~ to withdraw an excess of blood from the brain by making his patient stand with one arm outstretched until the limb aches violently. By conduct- ing the excess of blood to the arm in this way, the brain is relieved, and a cure speedily effected. Cold to the head is often of great benefit in the active form of the disease, if systematically applied. When the hyperaemia is intense and the pupils very much contracted, ice and ice- water should be applied to the head and neck until the symp- toms abate, which may not be under several days, or even weeks. I recently succeeded in curing a very severe case"in this manner, in a patient over seventy years of age, and a hard drinker at that, the congestion continuing over a period of from six to eight weeks, more than four hundred pounds of ice being used! Of course, such heroic treatment is only suited to cases of the most active and intense form, with a very high temperature, bounding pulse and greatly contracted pupils. In mild cases it will be better and safer to use warm water in- stead of cold, as the evaporation from it not only produces a comfortable sense of coolness, but causes no depression, and is followed by no injurious reaction. There are various agents known to possess the power of con- tracting the cerebral capillaries, such as galvanism, ergot and the alkaline bromides. These are sometimes useful as pallia- tives, and may be employed with benefit in cases where the homoeopathically indicated remedies, from any cause, appear to be inadequate to the complete removal of the hypermmic condition, which, however, will seldom be found to be the case. The constant galvanic current should be applied by placing one sponge over the sympathetic nerve in the neck, and the other over the spine, opposite the seventh cervical vertebra. The current from eight or ten Smee’s or Leclanché cells, acting not to exceed three or four minutes at any one time, will be sufficient for the purpose. Ergot and the bromides, being allopathic remedies, require to be used in material doses. Hammond advises the former in drachm doses of the fluid extract, and the latter in twenty- grain doses, in solution, three times a day. I have seldom had CEREBRAL HZEMORRHAGE. 21 occasion to resort to either of these remedies in active cerebral congestion, but have employed the bromides with apparent benefit in a few stubborn cases, giving them in two or three- grain doses every hour. Care should be taken in every case to keep the feet warm, the head elevated, the chamber cool, and the clothing about the chest and neck loose and comfortable. The diet should be light and easily digestible; and in all severe cases it should be entirely devoid of any stimulating quality. I have found nothing better, for this purpose, than a thin broth made of a bare knuckle of veal, and containing little 1nore than water and gelatine. CEREBRAL HJEIVIORRHAGE. Syn0nyms.—Apoplectic Stroke, Cerebral Apoplexy, Apo- plexia Sanguinia; Fr., Hemorrhagie Cérébrale Interstitielle; Ger., Hirnschlag, Schlagfluss, Gehirn-apoplescie, Hirnblutung. Definition.—A rupture of a cerebral bloodvessel, and the consequent escape of blood into the substance, or into the ven- tricular cavities, of the brain. Diagnosis.-—The distinctive character of cerebral haemor- rhage is that of a brain lesion occurring suddenly. But as apoplexia sanguinia is but one form of the apoplectic state, it is important to distinguish it from the others, namely, the apo- plectic variety of cerebral hyperaemia, embolism of cerebral arteries, alcoholic and uraemic intoxication, sunstroke and haemorrhage into the cerebral membranes. The distinctive features of cerebral congestion have already been given under the head of cerebral hyperaemia, which see. Embolism of the cerebral arteries may commonly be dis- tinguished from cerebral haemorrhage by the fact that in em- bolism there are no prodromic symptoms, that the paralysis is usually on the right side, and that the disease is almost always associated with valvular disease of the heart. The symptoms of alcoholic and uraemic intoxication some- times closely resemble those of cerebral haemorrhage, but the profound stupor of full inebriation can usually be satisfactorily determined by the breath, habits and general appearance of 22 NERVOUS THERAPEUTICS. the patient; while uraemic intoxication offers a suflicient guide to the judgment in the existence of kidney disease and the chemical and microscopical peculiarities of the urine. The insensibility produced by sunstroke can be easily ac- counted for by a knowledge of the previous exposure of the patient to the direct rays of the sun, while the absence of one- sided paralysis clearly distinguishes it from cerebral hmmor- rhage. Haemorrhage into the cerebral membranes may usually be distinguished from cerebral haemorrhage by the fact that it is seldom followed by hemiplegia, that violent headache is a characteristic symptom of it, that coma comes on gradually or not at all, and especially by the fact that its course is marked by frequent remissions. ' Hysterical coma often closely resembles that of cerebral haemorrhage, but in these cases there are usually other evi- dences of the hysterical condition present, such as the super- ficial character of the symptoms, the unerhbarrassed state of the general circulation, the absence of stertor, the age of the patient, the hysterical history and constitution, etc. Pathology. ——MM. Charcot and Bouchard have conclu- sively shown that, in the great majority of cases of cerebral haemorrhage, the vascular rupture is due to the formation of rniliarg aneurisms upon the smaller branches of the cerebral - arteries, in consequence of an inflammatory condition which results in atrophy of the middle coat, on which their strength chiefly depends. The cerebral bloodvessels are also sometimes greatly weakened by atheromatous degeneration, which is a common pathological condition in the aged, and is sometimes the only known cause of the rupture. Other conditions, like- wise, doubtless favor the rupture, such as an increased tension of blood in the vessels of the brain; an unhealthy state of the blood, such as exists in typhus, scurvy, etc., rendering it unfit for the proper nourishment of the bloodvessels, cerebral softening, etc. Clinical Experience.—Aconite and Belladonna are generally given to relieve the earlier and premonitory symptoms, the former being preferred when there is much arterial excite- CEREBRAL HEMORRHAGE. 23 ment, and the latter when congestion is the most prominent symptom. Phosphorus not only retards calcareous degeneration, but nourishes the brain substance, thereby lessening the danger of vascular rupture, and is given whenever, from hereditary predisposition, or tendency to cerebral congestion, an attack of sanguineous apoplexy is apprehended. During the attack, and until sensibility returns, the chief reliance usually is upon Opium, aided, according to the state of the circulation, by Aconite and Belladonna. At a later period, Arnica, Rhus tox., Nux vom. and similar remedies are usually resorted to, partly to promote the absorption of the clot, and partly to stimulate the nerve centres, and thus relieve the paralytic condition. Therapeutic Indications.—Phosphorus.——Probably this is the most important remedy, so far as preventive treatment is concerned, for the reasons above stated. Hereditary predisposi- tion to the disease, a weak condition of the nervous system, the existence of senile or scrofulous bronchitis, weak lungs, cough, night-sweats and loss of memory, all point to the early use of this remedy, especially in the aged, and more particularly if subject to transient attacks of cerebral congestion. Aconite is another 'very important remedy, as well in the premonitory as in the inflammatory stages. Whenever the head is hot, the pulse full, hard and strong, and the patient complains of headache, thirst, numbness and formication, this remedy is especially indicated. Belladonna should follow Aconite, both in the premonitory and initial stages of the disease, whenever the symptoms for which the latter is given fail to yield, or when the head be- comes hot, the eyes red and bloodshot, the pupils contracted, the face flushed and the cerebral vessels throb with increased violence. Convulsive movements, when spontaneous, are an additional indication for this remedy. Opium rivals all other remedies during the stage of insensi- bility or when the face is dusky red, puffed and a deep coma- tose state exists, with stertorous respiration, slow, irregular breath- ing, dilated and insensible pupils, face and head covered with cold sweat, dropping of the lower jaw and one-sided paralysis. Baryta carb.——Sanguineous apoplexy of old people, especially 24 NERVOUS THERAPEUTICS. when accompanied with partial paralysis, the patient being unable to speak owing to paralysis of the tongue; anxiety, with trembling of the limbs, and an inability to maintain the body in an erect position; childish, fearful and forgetful. Specially suited to those addicted to the excessive use of strong drink. Rhus t0x.—-This remedy may be given with advantage after the inflammatory symptoms subside, especially when there is a loss of feeling as well as of motion. Rheumatic pains in the un- paralyzed side, especially if aggravated by damp weather, also point to the use of this remedy. Arnica.—Paralysis of the left side of the body, with insensibility and stertorous breathing; muttering delirium, with involun- tary discharges of faeces and urine; symptoms of shock in old people; also suitable for the middle-aged, possessed of strong, plethoric constitutions. Arnica stands high as an anti-paralytic remedy in these cases, owing to its power of promoting the ab- sorption of the clot, or, rather, of the effused blood, whereby the clot is contracted and the paralysis correspondingly re- lieved. SanguinaI'ia.—Attacks due to venous congestion; distension of the temporal veins; burning heat and redness of the face; burning of the ears; paralysis of the right side; bad odor of the . breath and sputa; diflicult respiration, with pain in the chest, and cough. Especially suited to cases complicated with senile bronchitis. Nux Vom.—Sanguineous apoplexy of high livers, professional men and those leading a sedentary life; stertorous breathing, stupefaction and paralysis; dropping of the lower maxilla; attacks preceded by premonitory symptoms, such as vertigo, headache, tinnitus aurium, etc., also for the premonitory symptoms themselves. Pulsatilla.-—Attacks attended by loss of consciousness and preceded by drowsiness, especially when occurring in women at the climacteric period, or when accompanied or preceded by an arrest or disturbance of the menstrual function; con- gested condition of the face, with difliriult breathing and pa- ralysis. Lachesis.—Insensibility, with sopor or drowsiness; absence CEREBRAL HZEMORRHAGE. 25 of mind when conscious; congestion to the head, with blueness of the face; slow, heavy, wheezing respiration ; full and hard, or weak and irregular pulse; paralysis, especially on the left side. Laurocerasus.—Deep, quiet coma, more like natural sleep than usual in such cases; pulse scarcely perceptible; cold, clammy skin; palpitation of the heart; convulsions, with sub- sequent paralysis, including paralysis of the sphincters; defi- cient susceptibility to the action of other remedial agents; patient speechless even when conscious. Sepia.—-Attacks preceded by cerebral hyperzemia or by ve- nous congestion; intermitting pulse, cold feet and palpitation of the heart; intense headache coming on suddenly after stop- page of the menses. Especially adapted to women at the climacteric period, and to men addicted to hard drinking and venery. Auxiliary T1'eatment.—Inasmu ch as, according to the old adage, “an ounce of prevention is worth a pound of cure,” great care should be taken in all cases where, either from age and decrepitude, or from hereditary predisposition, there is reason to apprehend an attack of cerebral haemorrhage, to guard against its occurrence by a timely administration of such remedies as will tend to improve the blood and strengthen the enfeebled capillaries of the brain, such as Phosphorus, Nua: vom. and Baryta, and also to quiet the circulation and subdue any tendency to cerebral hyperaemia which may exist by such remedial measures as we have recommended under that head. (See the preceding section, and for fuller information on this important subject the reader may also consult with advantage the author’s work on Intracranial Diseases, pp. 99-108.) After the attack, and especially during the period of uncon- sciousness, the patient should be kept in such a position as will most favor a return of blood from the head. Thus the head and shoulders should be raised by pillows, the clothing loosened about the neck and chest, and free ventilation of the patient’s room at all times‘ secured. The paralyzed limbs should be wrapped in cotton batting, or kept warm by means of hot fiannels, frictions, etc.; and the bowels should be relieved 3 26 NERVOUS THERAPEUTICS. from time to time by emollient or stimulating injections, as the exigency of the case may require. Attention should also be given to the bladder, and, if necessary, the catheter should be used daily until the patient is able to void his urine voluntarily. The diet is such an important matter that during the early stages of the attack nothing more stimulating than gum water, barley or rice water, toast water and similar farinaceous drinks should be given ; but after the period of inflammatory danger is past and improvement commences, more nutritious sub- stances may be allowed, such as animal broths, milk, soft- boiled eggs, etc., but the effects produced by administering such articles of nourishment as these should be carefully watched, and if, on strengthening the diet, the face becomes flushed, and headache and restlessness or increased stupor en- sues, all such stimulating articles of diet should be at once withdrawn. If inflammation sets in around the clot, which is apt to occur about the ninth or tenth day of the seizure, the treatment for meningitis and encephalitis will be required. No attempt should be made to overcome the paralysis until the period of inflammation is past and the acute symptoms have entirely disappeared. Measures may then be safely taken for the relief of the paralysis, and for the prevention of consecutive muscular contractions. One of the first measures to be employed for these purposes is massage, which should be administered from one to three times daily by an experienced masseur. Some benefit may also be obtained from friction with the flesh brush and salt water, or with the electric brush) which is still more stimulating. But the most efficient treat- ment of the sort is galranism methodically applied. At first, the induced current is to be preferred, but it should be of sufficient strength to produce contraction or cause slight pain. It may be applied by means of wet sponges to the skin cover- ing the muscles, or, if this proves ineffective, it may be applied directly to the nerves. Such cases as will not yield to the in- duced current, whether they be Old or recent, should be treated with the primary interrupted current, the primary constant current not producing contractions. The same efficient agent CEREBRAL THROMBOSIS. 27 may be used to promote the restoration of sensibility, in cases in which the anaesthesia does not spontaneously disappear. After the patient has so far recovered as to move about, moderate exercise in the open air, change of scenery, salt- water baths and a diversified but tranquil life are to be com- mended and, as far as possible, secured. CEREBRAL THROMBOSIS. Synonyms.-———Thrombosis of Cerebral Arteries, Veins and Sinuses; Fr., T hrombose Gérébrale; Ger, Thrombose Cerebralis, Hirnarterienversperrung, Thrombose der Hirnarterien. Definition.——An occlusion of cerebral arteries, veins or sinuses by the coagulation and deposition, in situ, of fibrin upon the internal coats, or within the lumen, of the vessels. DiagnosiS.—The diagnosis of cerebral thrombosis is often a matter of extreme difficulty. The disease may be distin- guished, in a general way, from cerebral embolism and cerebral haemorrhage by the gradual manner of its development; but from cerebral heemorrhage, when, as is sometimes the case, the haemorrhage takes place gradually, it can only be certainly diagnosed by taking into consideration the predis- posing causes, namely, pulmonary affections and valvular diseases of the heart. Wlien there is valvular disease, the diagnosis between cerebral thrombosis and cerebral embolism may be satisfactorily made out by means of the following table: Cerebral Thrombosis. Cerebral Embolism. Advanced age. Youth. Evidences of atheroma. Absence of atheroma. Fatty degeneration of heart. Previous rheumatic attacks. Slight attacks of paresis. Decided paralysis. Path0logy.—Owing to the diseased condition of the blood- vessel its internal coat becomes roughened, which favors the deposition of fibrin at that point. The primary layer thus formed becomes gradually thickened by fresh accretions, until 28 NERVOUS THERAPEUTICS. finally it fills the whole caliber of the vessel and completely obstructs it. While the artery is undergoing occlusion the part of the brain to which it is distributed is rendered more or less anaemic, and when the vessel becomes entirely closed the anaemic parts undergo the process of softening—flrst, red soft- ening (which is probably a state of passive hyperaemia, com- bined with oedema and haemorrhage), and afterwards, unless the collateral circulation is speedily and adequately established, necro-biotic or yellow softening quickly supervenes. Clinical Experierme.—As this disease, when fully devel- oped, depends upon the presence of foreign matter lying be- yond the reach of ordinary remedial agencies, little benefit has hitherto been derived from medical treatment; nor can much benefit be reasonably expected from such treatment in any case, except so far as it may be capable of retarding the pro- gress of the disease, and in contributing to the relief of some of its most serious and distressing symptoms. How far the following plan, prescribed by Dr. Stiles, has proven eflicacious I have no means of knowing, but that it will palliate such cases I have no doubt. Wl16I1 the disease shows evidence of inflammatory action, or is recent, Bellad., Nua; vom., Mercur.; where it is evidently due to atheromatous conditions of arteries, Phosphor, Phos. ac., Anac., Zincum; for hemiplegia, Nua; vom., Coccul, Baryta carb., Arnica; for vertigo, Iodine (congestive); Sulphur, Digit. (cardiac); for sleeplessness, Coflea, Hyosc. or Nun vom., and O'hamom., if the patient has been addicted to the use of coffee; China, if he has been a great tea drinker; for paralysis (general), Phosphor, Conium, Coccul. (local), Caustic, Acon., Ignat., Bellad.; for con- vulsions (simulating epilepsy), Bellad, Cale. carb., Cuprum, Strychnine; for emotional disturbances, Ignat; headache (ac- tive), Acon., Bellad., Bryon, Nurc vom., Glonoin; (passive), Gelsem., Opium; for imbecility, Arnica, Ambra, Selen., Sepia; or sensation of formication, Secale. Therapeutic Indicati0ns.—These, so far as applicable to the disturbances caused by cerebral thrombosis, may be found under the respective heads of cerebral anaemia, cerebral hyperaemia, cerebral haemorrhage, and encephalitis, which see. cEREBRAL THROMBOSIS. 29 Auxiliary Treatment.—This consists for the most part (1) in the removal, so far as possible, of all debilitating causes and disturbances; (2) in aiding both the general and local circula- tion by such constitutional and other means as the exigencies of the case may require; and (3) in endeavoring to dissolve the fibrinous deposit by the administration of alkaline solvents. Dr. B. W. Richardson, after citing a number of illustrative cases, formulates the following rules, among others, for the exhibition of Ammonia as a solvent of fibrinous concretions in the heart and bloodvessels: 1. The ammonia is best administered either in the form of the strong aqueous solution, or of the saturated alcoholic solu- tion. More than five minims at a time cannot easily be swal- lowed. The best menstruum for the ammonia is milk, and if the milk be chilled by ice, the patient takes the mixture with great facility. 2. The ammonia must be relied upon exclusively. Seda- tives and stimulants of all kinds are to be avoided as fraught with danger. Wines-and spirits are most injurious; they pro- duce a danger of movement of the fibrinous mass; they excite and, in time, exhaust the heart. 3. The diet should be, as nearly as possible, of pure milk, with a11 occasional change to gravy soup or minced codfish, with bread or toast. Other solid substances do not digest readily; they create fiatulency, and cause a restless movement of the body, which is detrimental. 4. With the medicinal and dietetic treatment thus enjoined there must be combined the most perfect rest of the body in one position. The secret of success consists in producing solu- tion of the obstructing mass while it lies sufficiently out of the course of the circulation. If it loosen from its hold while it remains semi-solid, however small it may be, it will be a source of additional danger. 5. Together with this physical rest, every mental comfort must be supplied. The patient must be harassed with no unnecessary fears, agitated by no unnecessary comments. Much of the success of the treatment depends on the gentle firmness with which the practitioner enforces that the greatest 30 NERVOUS THERAPEUTICS. advantage is secured by absolute repose of the mind as well as the body. 6. \Vhen the secondary changes indicate the solution and distribution of the fibrin, the administration of the ammonia is not to be immediately withdrawn. The alkali is still as im- portant, under these circumstances, as in those which precede them. ‘ 7. The conditions warranting the withdrawal of the solvent are: relief of venous engorgement; normal return of pulse and temperature, and restored mental and physical power; i11 other words, a complete restoration of all the normal powers and functions. When these favorable conditions exist, it is fair to infer that no obstruction remains in the circulatory canals, and that the ammonia may be safely withdrawn. But inasmuch as the ammonia, however far it may, with reason, be carried, does no injury that is not quickly recovered from, there exists.no cause for hurry in withdrawing it. It may, therefore, be continued in less frequent doses for a few days after every danger appears to have-passed away. The above directions have been formulated with reference, more especially, to embolism and thrombosis of the larger circulatory vessels, but they apply equally well to the same conditions of the capillary vessels of the brain, except that, in the latter case, the injunctions as to absolute rest need not be insisted on to so great an extent. Nevertheless, it is important even in these cases that the complete solution of the fibrinous obstructions should take place in situ, unless the general health of the patient should materially suffer from the confine- ment; hence it is best to have them rigidly observed in every case of cerebral vascular obstruction in which the treatment may be tried. CEREBRAL EMBOLISM. Synonyms.—Embolism of the Cerebral Arteries and Capil- laries; Fr., Embolie Oérébrale; Ger., Embolie Cerebralis, Hirn- arterienoersperrung, Embolie der Hirnarterien. Definition.--The obstruction of arteries or capillaries of the brain by solid particles of matter formed in other parts of CEREBRAL EMBOLISM. 31 the body, and carried along in the course of the circulation to points where they have become lodged. Diag‘n0sis.—Occlusion of the left middle cerebral artery causes right hemiplegia with aphasia, while obstruction of the right middle cerebral produces left hemiplegia without aphasia. Embolism of the ophthalmic artery gives rise to sudden am- aurosis; and sudden plugging of the basilar artery produces vomiting. These diagnostic points are sufficient, in connection with the other symptoms mentioned below, to clear up the majority of cases of cerebral embolism; but when the symp- toms of apoplexy are present it may not be possible at first to distinguish the disease with certainty from cerebral haemor- rhage. When, however, the paralysis vanishes suddenly, we know that it was not caused by cerebral haemorrhage; and if recovery takes place within two or three days after the attack, the latter can only be referred to an embolus. Moreover, there are no premonitory symptoms in embolus; the disease occurs irrespective of age; the paralysis, which is usually on the right side, is generally combined with aphasia; and the disease is almost always associated with valvular disease of the heart, or a preceding attack of endocarditis. The differential diagnosis between cerebral embolism and cerebral thrombosis may be found under the latter head. Path0logy.—Many competent observers have shown that the cerebral bloodvessels may be obstructed by fibrinous con- cretions derived from the heart or large vessels; that this obstruction produces anaemia of those portions of the brain to which the affected artery is distributed; and that unless the obstruction is quickly removed, or the collateral circulation adequately and speedily established, softening of the brain substance is sure to follow. Anomalous cases of cerebral embolism sometimes occur, in which general fever takes the place of hemiplegia or other local paralysis. These cases are characterized by high fever, with delirium, and without any, or scarcely any, definite pa- ralysis or aphasia. The pathological condition consists in the distribution through the brain of embolic dust, so fine as to traverse without hindrance the larger arteries of the base and 32 NERVOUS THERAPEUTICS. substance of the brain, to be finally arrested in the minute channels of the pia mater. Clinical Experience.—-The only clinical experience worth mentioning is that referred to under the head of thrombosis, which see. Therapeutic Indications.——As these have to do with eflects rather than causes, they will be found given in detail under their appropriate headings. See cerebral anaemia, hyperaemia, hannorrhage and softening. Auxiliary Treatment.—This is necessarily limited to such measures as are calculated to favor the establishment of the collateral circulation, to wit: lowering or raising the head, ac- cording as the cerebral circulation is more or less embarrassed; promoting the general circulation by friction with the flesh brush, wrapping the body and limbs in warm blankets, cotton batting, etc., in case the patient is somnolent and the bodily temperature much reduced; and, finally, by a cautious en- deavor to dissolve away the flbrinous concretions by the “ammonia” treatment already described. (See p. 29.) ENGEPHALITIS. Syn0nyms.——Suppurative Inflammation of the Brain, Cere- britis; Fr., Inflammation de l’Encephale; G'er., Enkephalentziln- dung;—-Cerebral Abscess; Fr., Abcés Cérébrale, Abcés de l’Ence- phale; G'er., Eiterbeule des Gehirns, H irngeschwiir. Definiti0n.—Partial inflammation of the brain substance, usually complicated with meningitis, and tending to sup- puration. _ Diagnosis.—The diseases for which encephalitis is liable to be mistaken are: acute cerebral meningitis, cerebral haemor- rhage, cerebral tumors, and the disease called general paralysis. In acute meningitis the fever is much higher, the convulsive movements more general, the headache more severe, and the delirium more marked and constant. In cerebral haemorrhage the symptoms generally become more and more ameliorated as the disease progresses, whereas in encephalitis they become progressively more pronounced. The symptoms which charac- ENCEPHALITIS. 33 terize general paralysis, and also those which attend the de- velopment of cerebral abscesses, closely resemble those which accompany the growth of cerebral tumors, and can, as a rule, only be distinguished by the history of the case and the fact that encephalitis is usually of shorter duration than general paralysis, and is not marked by the “mania de grandeur” peculiar to the latter disease. Pathology.—The tendency to suppuration is so great in this disease that more or less softening of the brain substance is always found after death, generally in circumscribed patches, which usually terminate in one or more abscesses, involving not only the gray matter, in which the inflammatory process usually commences, but also the white substance of the cere- brum, the basal ganglia, and, in some cases, the cerebellum. In acute cases, the abscess, being surrounded by no limiting capsule, encroaches more and more upon the adjacent tissues, and may ultimately reach the surface of the brain, or break through into the lateral ventricles. When the inflamination is due to injury or caries of the cranial bones, it is no uncom- mon thing for it to escape, sooner or later, through the ear or nose. On the other hand, when the inflammatory process is more chronic, the abscess is surrounded by a membranous capsule composed of connective tissue, and if large will give rise to symptoms of compression. There is no hope of recovery after the disease has passed the stage of red softening. Clinical Experience.—Our clinical experience in this dis- ease is so mixed up with that of acute meningitis, with which it is commonly associated, that no reliable distinction can be made between them. This, however, is of but little conse- quence in a practical point of view, as the treatment of sup- purative encephalitis is, so far as our present experience goes, altogether palliative. It is right to add, however, that Kafka ap- pears to have treated a case successfully with Arsenicum, “ even when cerebral softening, with progressive increase of the mor- bid phenomena, coéxisted side by side with the symptoms of cerebral hyperaemia,” the remedy having been employed after the hyperaemic condition had been relieved by Glonoin and Belladonna. Kali brom. and Cannabis ind. have proved bene- 34 NERVOUS THERAPEUTICS. ficial in some cases by diminishing the irritability of the nervous system. Therapeutic Indications.—Considering, as we do, that the curative stage of this disease is limited to the initial or hyper- aemio period, to detail the therapeutic indications would be but to repeat what is said under that head regarding cerebral hgperarnia and rneningitis. We will simply add that Iodine and Plurnbum have been recommended, chiefly on theoretical grounds, the former for its supposed power to control suppu- rative inflammation, and the latter for its anti-paralytic action ; Jllercurius iod. in syphilitic and scrofulous subjects, especially when there is a history of chronic otorrhoea, enlarged tonsils or rheumatism, with an aggravation of the symptoms at night or from a change of weather; Pulsatilla, when the disease follows the suppression of an eruption or of a chronic discharge from the ear; Silicea, when an abscess is supposed to have formed; and Zincwm in the later stages, when there is great depression of both mind and body. Auxiliary Treatment.—Hygienic measures, if instituted sufficiently early, may be of service in warding off an attack. Hence, in all suspicious cases, especially if the patient is weak, scrofulous or ill-nourished, a good nutritious diet should be recommended, and, where vertigo does not prevent, the patient should exercise freely in the open air, live in a mild, equable climate, and, if practicable, occasionally take an ocean voyage —all of which will strongly tend, by invigorating the system, to remedy any threatened invasion of the disease. CEREBRAL SOFTENING. Synonyms.—Softening of the Brain; Fr., Ramollissernent Cérébrale; Ger, Erweichung des Gehirns. Definition.——A necro-biotic process, involving brain tissue, caused by defective nutrition, depending in most cases on vas- cular obstruction and attended by diminished consistence. Pathology.-When obstruction in any of the cerebral blood- vessels takes place on the far side of the circle of Willis, necro- biosis is quickly established, because there is no free vascular CEREBRAL SOFTENING. 35 connection by which a collateral circulation can be speedily effected. Hence the parts supplied by the obstructed vessels at once become anaemic, and, nutrition being cut off, a condi- tion known as red softening, i.e., hyperaemia, with oedematous swelling and haemorrhage, soon supervenes. Subsequently, the color, which is due entirely to the extravasation of red corpuscles, gradually fades, and in a few weeks the affected tissues present the appearance of yellow softening. In case the patient survives a sufficient length of time white softening is produced, the cerebral matter changing into milk-like emul- sion, part of which eventually becomes absorbed, leaving in some cases a cyst partially filled with liquid, resembling the cysts found after ordinary attacks of cerebral haemorrhage. There is another condition, called primary yellow softening, in which the parts immediately undergo fatty degeneration, without the previous changes above mentioned. This is sup- posed to depend upon a weakened state of the heart, the blood coagulating so quickly in the sphere of the obliterated vessel as to prevent any reflux of blood through the corresponding vein. ' Clinical Experience.—BeZladonna, Kali phos., Rlzus t0x., Glo- noin, Picric ac. and Arsenienni have all been given with apparent success in this disease——I say, with apparent success, because I do not believe it to be within the power of any remedy to effect a cure after the stage of red softening has passed, even though the vascular obstruction should have ceased. Up to and including this stage, however, these remedies have given good results; indeed, more or less amelioration of the symptoms has been produced by them at a comparatively late period in the disease. So far as the pathological condition of the brain is concerned, Arsenicmn and Picric ac. are eminently homoeo- pathic to it, and if it be possible to set up a curative action in the affected tissues at this stage of the disease, these are the remedies most likely to prove successful. Therapeutic Indications.—Picric ac.—-Necro-biotic soften- _ ing of nervous tissue; intense cerebral hyperaemia; bleeding of the nose; cerebral softening; extremities feel heavy, cold and very weak; speedy exhaustion from slight exertion; general state of asthenia. 36 NERVOUS THERAPEUTICS. Arsenicum.-—Necro-biotic softening; headache, vertigo, wan- dering pains, impaired sensibility of the limbs, delirium, coma, lassitude, nervous debility, cramps, trembling, paralysis. Strychnia.—Cerebral softening, accompanied by hemiplegia, or by general paralysis. Zincum phos.—Severe headache, dizziness, sleeplessness, loss of memory, cardiac weakness; general debility. Belladonna-—Fixed headache, with drowsiness, vertigo and loss of memory; convulsions; local paralysis. AbI'otanum.—Gloomy, despondent, irritable, ill-natured; brain easily fatigued; head weak; face pale and wrinkled; indolent and averse to physical exercise. Auxiliary Treatment,—As embolism and thrombosis are the two principal causes of cerebral softening, the auxiliary, no less than the special, treatment recommended for those conditions applies with equal force to this disease, and need not therefore be repeated. The same is true of the treatment recommended for cerebral hyperaemia and hmmorrhage, con- ditions which belong especially to the curative stage of this affection. Indeed, it is only by directing the treatment in this way against individual symptoms and conditions that we can stand any chance of curing, or even of greatly ameliorating, the cerebral disorder. From what has been said regarding the aetiology and path- ology of cerebral softening, it follows that any influence or treatment calculated to lower the tone of the system, no matter what it may be, must have a prejudicial effect, and consequently that the early adoption and steady use of supporting measures are of the highest importance. If the general circulation is much embarrassed, or if the patient is much reduced in strength or his mind greatly impaired, he should be kept in a quiet, recumbent position, the body and extremities kept warm by artificial heat, friction, etc., and all intellectual e'xertion and every form of mental and bodily excitement should be care.- fully avoided. ' APHASIA. 37 APHASIA. Syn0nyms.—Loss of the Faculty of Speech, A phemia, Alalia; Fr, Aphasie; Ger., Sprachltthmung, Aphasie. Definition.--A disease of the brain attended by a loss of memory of words, or of the ability to express them in written or articulate language. Diagnosis.—-This disease is easily recognized, as there is no other affection with which it is liable to be confounded. VVhen due to cerebral haemorrhage, thrombosis, embolism, abscess or tumor, it is almost invariably associated with right-sided hemi- plegia; but in simple cases, such as are caused by mere func- tional derangement, irritation, oedema, congestion, etc., there is little or no attending paralysis, and the prognosis is far more favorable. Pathology.—-Broca first made the discovery that the cere- bral centre for articulate language is in the third left frontal convolution of the brain, along the course of the middle cere- bral artery in the island of Reil; and that irritation or injury of this portion of the cerebrum causes aphasia. This discovery has since been abundantly confirmed by numerous post-mortem examinations, from which it appears that the disease is usually due, in fatal cases, to the blocking up of the left mid- dle cerebral artery by an embolus or thrombus. Clinical Experience.—Notwithstanding the fact that apha- sia is often due to occlusion of the middle cerebral artery, it is a singular fact that many cases of the disease have yielded to homoeopathic treatment; from which we infer that, contrary to the usual belief, aphasia results far more frequently from irritation or congestion than from organic disease. Decided improvement and, in many cases, satisfactory cures have been reported from the use of Belladonna, Arnica, Stramonium, Phos- phorus, Glonoin, Baryta, Lachesis, Kali bronv, Causticum, Lyco- podium, Zincam, Conium and Bothrops. Therapeutic Indications.-—Lycopodium.—Makes many mis- takes in reading and writing; uses wrong words, and words which do not express what he wants to say; mixes up letters and syllables, and leaves out part of them; is very forgetful, and troubled by confusion of thought. 38 NERVOUS THERAPEUTIOS. StI'amonium.—Talks at random, using a perfect diarrhoea of words without rational meaning; confusion of intellect, with great weariness of mind; congestion of the brain, with con- tracted pupils, and almost complete blindness; stuttering; paralysis of the organs of speech; loss of memory; unconscious- ness; extreme insensibility of all the senses. Conium.—Very forgetful, especially of words; cannot under- stand what he is reading; uses wrong words in speaking; loss of memory, with great confusion of mind; entire loss of the power of speech; hesitating and difficult speech; somnolence, amounting to stupefaction. Arnica.—-Aphasic symptoms following an attack of cerebral haemorrhage; stertorous breathing; bruised, aching feeling iii the brain; paralysis. Glon0in.—Loss of memory for words and of the power of expressing them; acute congestion of the brain; mental torpor. Baryta caI'b.—Loss of memory for words and names; cannot recollect the names of persons or things; great dulness of mind and of the senses. Lachesis.--Dulness of comprehension; does not understand what he reads or hears; loses the sense of words; makes mis- takes in writing; confuses numbers and dates; absence of thought, with great weakness of memory. Kali iod.—In syphilitic and epileptic cases; also when the aphasic symptoms have been preceded by an attack of cerebral haemorrhage. Phosphorus.—In cases where the symptoms preceding the attack show general depression of the nervous system, as mani- fested by weakness, mental torpor, restlessness and indecision. Caustioum.—Great weakness of memory; very forgetful of words and names; head feels heavy and dull; absentmind- ness; congestion of the brain; inability to think clearly on any subject. Colchic11m.—Inability to pronounce words correctly; loss of memory for words; leaves out words and syllables in writing; confusion of thought. Ghamomilla.-—Omits words in speaking and writing; is very forgetful and absentminded; great dulness of comprehension; mental vacuity; stammering hesitancy of speech. CEREBRAL HYPERTROPHY. 39 There are many other remedies the pathogeneses of which contain aphasia symptoms, among which are: Olean., Thuja, Anac., Graph, Ign., Natr. mur., China, Rhodod., Crocus, Arg. nit., Hepar sulph., Merc., Puls., Nux vom., Nux mosch.; others, like Opium, CEnan., Bell., are eminently suited to apoplectic conditions; Hyosc., Bovis., Phos. ac., Cocc., Alum., P1at., when absentminded and forgetful; Sulph. ac., Amm. carb., Sepia, Bov., awkwardness of expression. Auxiliary Treatment.—Prof. Charcot has attempted to show that the power to pronounce or to write words depends upon an impression made upon the ear or eye, and therefore that every aphasia or agraphia is a word amnesia situated in some central ganglion of the brain, instead of being confined, as is generally thought, to Broca’s convolution. If Charcot’s doctrine is correct, then much may be done in chronic cases towards_recovering the faculty of speech, by educating, so to speak, the corresponding sense centre. We know that some- thing like this has already been accomplished in a number of instances, but it has generally been referred to the “unedu- cated” third frontal convolution of the opposite side of the brain, namely, the right. May it not be possible, in these cases, by careful practice every day, to so educate the previously unused sense centres presiding over the faculty of speech, as to greatly favor a cure, and in time, perhaps, overcome the difficulty altogether‘? CEREBRAL HY PERTROPHY. Synonyms.—l-Iypertrophy of the Brain, Hyperplasia of the Cerebral Neuroglia, Hypertrophia Cerebri; Fr., Hypértrophie Cérébrale, Iiypértrophie dit C’erveaw; Gen, Hypertrophie des Gehirns, Gehirn-hypertrophie. Definiti0n.—An overgrowth or hypertrophy, not of the nervous tissue, but of the neuroglia, or interstitial connective tissue of the brain. Diagnosis.-—-In congenital cases, owing to the enlargement of the head, the disease is liable to be mistaken for chronic hydrocephalus; but children affected with cerebral hyper- 40 NERVOUS THERAPEUTICS. trophy are mentally brighter and more precocious than usual, while the subjects of hydrocephalus are unusually dull and stupid. In other cases the diagnosis is more or less uncertain, but when the enlargement is attended with frequent attacks resembling epilepsy, its existence is highly probable. Patho1ogy.—On exposing the surface of the brain in situ, it immediately expands so as to overlap the bones of the cranium ; but a careful examination shows that while there is no undue amount of cerebral matter present, there is an ex- cessive development of the neuroglia, rendering the brain heavier, firmer and more elastic than the normal organ. Clinical Experience.——It is not certain that the disease has ever been materially benefited by medical treatment. Calcarea carb., Phosphorus, Kali iod., and a few other reme- dies have been recommended, but only, I believe, on theoreti- cal grounds. Therapeutic Indicati0ns.—These pertain, almost exclu- sively, to the remedies usually employed in cerebral hyperaemia, convulsions, epilepsy and cerebral paralysis, and will therefore be found under those headings. Auxiliary Treatment.—-The most important accessory treatment in these cases consists in improving the general health, guarding against exposure to all injurious influences, relieving cerebral congestion when present, and abstaining entirely from the use of alcoholic stimulants. CEREBRAL ATROPHY. Synonyms.—Atrophy of the Brain, Atrophia Cerebri, Dif- fused Cerebral Sclerosis; Fr., Atrophie Cérébrale, Atrophie du Cerveau; Ger, Atrophie des Gehirns, Gehirn-atrophie. Definition.—-A shrinkage or wasting of the brain, with or without attending degenerative changes. . Diagnosis.—(/longenital cases are, as a rule, easily recogniz- able, as they constitute various grades of idiocy; but partial cerebral atrophy, which is usually due to local lesions, such as haemorrhage, softening and encephalitis, and general cerebral atrophy, which occurs mostly in the aged, and is attended with CEREBRAL ATROPHY. 41 a gradual loss of cerebral power, can only be conjecturally determined during life, and that most satisfactorily by the history of the case. Pathology.--In simple, that is to say, in primary or un- complicated cases, the brain is simply diminished in volume, owing to a contraction or shrinkage of its constituent elements, the cerebral cells, nerve tubes and arteries being all more or less contracted. . In the secondary variety, the neuroglia, or connective tissue element, becomes atrophied or sclerosed, producing a shrinkage of the convolutions, so that in some places they are widely separated; the ventricles and subarachnoid space contain a large amount of serum; and in some cases portions of the brain tissue undergo softening, apparently from inflammatory action, as the membranes are thickened and opaque. Clinical Experience,—This has reference exclusively to the physical, mental and nervous weakness experienced in these cases, as the atrophy itself cannot, of course, be remedied. The different salts of Baryta appear to have ameliorated the symptoms to a greater degree than any other remedies which have been tried. Therapeutic Indicati0ns.—These are such as pertain to the various lesions associated with the disease and their char- acteristic symptoms. As they may possibly be of some service in suggesting palliative treatment in certain cases, the reader will do well to consult the indications given under the several heads of cerebral heemorrhage, encephalitis, cerebral paralysis, con- vulsions and epilepsy. Auxiliary Treatment.—It is claimed that galvanism has been employed with occasional benefit in these cases, by pro- moting the nutrition of the atrophied cells. I have myself seen the paralysis diminish, the contractions relax, the mind improve and the wasted limbs gradually increase in size and strength under its stimulating influence. Both the induced and primary currents may be required, the interrupted secondary current being best for the paralysis, and the constant current for the relaxation of contractions. Ten Leclanché cells will generally furnish a current of suffi- 4 42 NERVOUS THERAPEUTIOS. cient intensity, the sponges being applied just behind the ears every second or third day, for a period not exceeding four or five minutes at one sitting. Such hygienic measures should be adopted as are best calcu- lated to improve the general health of the patient, since what- ever improves the health also improves nutrition. MULTIPLE CEREBRAL SCLEROSIS. Synonyms. —— Primary Multiple Sclerosis, Disseminated, Insular, Multilocular, or Idiopathic Cerebral Sclerosis; Fr., Sclerose en Plaques Disse’rninées; Ger., Multiple Slclerose des Ge- hirns. Definition.—-A cerebral lesion, consisting of plates or no- dules of sclerosed tissue scattered throughout the substance of the brain. DiagnoSis.——Primary multiple sclerosis is liable to be mis- taken for paralysis agitans; but in the latter disease there are no head symptoms, no muscular incoiirdination, no inability to trace a straight line with the dynamograph, no muscular anaesthesia, no abnormal states of sensibility, and is more apt to occur before than after fifty years of age. Secondary or as- cending multiple sclerosis may generally be distinguished by the fact that the tremor precedes the paralysis, and also by the fact that the trembling is associated with voluntary as well as with involuntary muscular movements. Chorea may be dis- tinguished from multiple sclerosis, not only by the history of the case, but by the facts that it usually occurs in young people, has no head symptoms, nor any actual tremor, the dis- orderly movements being simply more marked degrees of in- coordination, which render the movements more irregular and pronounced. Pathology.——The patches of sclerosed tissue are not confined to the hemispheres, though the cerebrum is their usual seat; they are occasionally found at the same time in the medulla, the pons and the cerebellum. Whether these cases are really different, as Hammond and others contend, from those in which the spinal cord is also implicated, is by no means cer- MULTIPLE CEREBRAL SCLEROSIS. tain. We know that multiple sclerosis is progressive, and we also know that in many cases the spinal form is secondary to that of the brain; but it does not follow that it is always so, nor that the disease, in such cases, is always an independent affection. What appears to be established is that, when con- fined to the encephalen, it gives rise to symptoms sufficiently characteristic to entitle it to be regarded as a distinct disease. Clinical Experience.——Arge/ntum nit. and Ovalic ac. stand at the head of the list in the treatment of this disease. Good results have also been obtained from Plumbum, Baryta, Zincum, Tarantula, Phosphorus, Sulphur and Rhus toss. Therapeutic Indications.—0xa1ic ac.--Lancinating pains like electric flashes in different parts of the body; electric-like pains in the forehead and vertex; sclerosis of nerve-tissue; tremor of the limbs; numbness of the fingers and toes. Argentum nit.—-Sharp, darting pains in the head, body and limbs; paralytic weakness in the back and limbs; trembling of the limbs; sensation of an epileptic aura; tremor increased by emotional esccitement; tingling, followed by numbness in the hands and feet. Plumbum.—Tearing, shooting pains from occiput to forehead ; paralytic weakness of the extremities, most marked upon the right side; atrophy of the muscular tissue, especially when arising from sclerosis of the cerebro-spinal system; trembling of the limbs; excessive pains in the limbs. Baryta 0arb.—Trembling of the hands and limbs, especially in old people; great bodily and mental weakness; facial paralysis; tremor of the feet when standing; arms heavy and tremulous; numbness and tingling in the fingers; shooting pains deep in the brain. Zincum 0xyd.—Jerking and trembling of the limbs; remark- able sinking of strength; paralytic weakness of the limbs, which tremble violently; tingling numbness in the limbs; painful ten- sion in the muscles when in action. '1‘arant11la.—Ghorea-like movements in the limbs; extreme restlessness; numbness of the trunk and limbs ; paralysis. Phosph0rus.—Cerebral paralysis; tearing pains in the fore- head and temples; numbness and formication in the limbs; 44 NERVOUS THERAPEUTICS. tremor of the hands; great restlessness and weakness; sensation as if completely paralysed. Sulphur.— Tremor of the hands; unsteady gait; tearing pains through the head, body and limbs; great debility and trembling; numbness and formication. Rhus tox.—Cerebral paralysis; trembling of the limbs; twitch- ing of individual muscles; numbness, both general and local; wavering sensation in the brain, especially when in motion; lacerating pains in the head, especially when stooping; aggra- vation of the symptoms during damp weather or just before a storm. Consult, also, the indications given under the head of cerebral paralysis, where a number of other remedies, of greater or less value in this disease, may be found. Auxiliary Treatment.—What is said under this heading concerning cerebral atrophy applies with equal force to multiple sclerosis. This is especially true regarding galvanism, and yet it cannot be doubted that, as a rule, electricity, in the indis- criminate way in which it is frequently used, has done almost as much harm as good. Overstimulation of any organ, espe- cially when its functional activity is impaired by organic dis- ease, is always more or less harmful, and this is emphatically true of the brain. Extreme care, therefore, should be taken whenever this potent remedy is employed in multiple cerebral sclerosis. ATHETOSIS. Syn0nymS.——HammOnd’s Athetosis; Fr., Athetose; Ger, Athetose. Definition.--A condition characterized by a slow, steady movement of the fingers and toes, and by an inability to re- tain them in any one position. ~ Diagnosis.-—The disease is liable to be mistaken for post- hemiplegic chorea; but the movements in this variety of chorea are quick, irregular, jerky and variable, while in athe- tosis they are slow, systematic and uniform. Pathology.—By some, athetosis is regarded as a symptom rather than a disease, as the cases so far observed are mostly CEREBRAL SYPHILIS. 45 found to be associated with some other nervous affection, such as hemiplegia, chorea and cerebral embolism; but as these all depend upon brain lesions, and, moreover, as bilateral athe- tosis often occurs in idiotic children, the affection in question is, I think, justly entitled to be regarded as a distinct disease. Its seat appears to be chiefly in, and just exterior to, the cen- tral cerebral ganglia——the corpus strictum and optic thalamus. Clinical Experience.-—0annabis ind., Arsenicum and A gari- cus have been credited with curative powers over this disease, and from its resemblance, in some cases, to chorea, it is not improbable that, when the central ganglia of the brain are in a state of irritation simply, these remedies may prove effective. Therapeutic Indications.——The cerebral symptoms in this disease being similar to those given under cerebral haemorrhage, chorea, epilepsy, cerebral embolism and paralysis, the appropriate therapeutic indications may be found under those headings. Auxiliary Treatment.-——Everything calculated to lessen irritation and build up the system is likely to be of service; hence good nutritious food and an abundance of fresh air are of prime importance. VVhere the intellect is impaired, as in the case of idiotic children, moral treatment may be neces- sary. Most patients in this condition have strong imitative faculties, and these may often be turned to good account. The primary galvanic current is reported to have been success- ful in stopping the movements after several months’ contin- uous treatment. The positive pole may be placed over the Spine or brachial plexus, and the negative on the affected muscles. CEREBRAL SYPHILIS. Synonyms.—Syphilitic Disease of the Brain, Cerebral Syphiloma, Gumma Syphiliticum Cerebri; Fr., Syphilis du Cerveau; Ger., -Hirnlustseuche, Syphilitische Gehirn-Erlcranlcung. Definition.-——Specific lesions of the brain and its membranes, congestive, vascular and gummatous, due to secondary and tertiary syphilis, especially the latter. Diagnosis.-—First in the order of importance is the his- tory of the case, which is often suflicient of itself to clear 46 NERVOUS THERAPEUTIOS. up the diagnosis; next, as pointed out by Brown-Séquard, the disorderly grouping of nervous phenomena should lead us to interrogate syphilis as a cause, as, for example, pa- ralysis of some muscle of the eye and paraplegia, or pa- ralysis of one hand and the other foot, etc. Age is also of great diagnostic importance, as paralysis occurring in youth- ful persons is, in the great majority of cases, of syphilitic origin. Violent paroxysmal headache is another character- istic symptom of the disease; there is no form of headache so intense as that which results from syphiloma of the dura mater. In case the patient has no clear syphilitic history, the differ- ence, which is often quite marked, between the real and appar- ent age, the facial expression, and especially the ophthalmos- copic symptoms are usually suflicient to establish the diagnosis beyond a doubt. The most reliable ophthalmoscopic symp- toms are: swelling, hyperaemia and oedema of the papilla, vari- cosity of the veins, and a peculiar form of neuro-retinitis and choroiditis known as syphilitic. Pathology.—The essential, gross pathological features of cerebral syphilis, according to Dr. Dowse, include (a) inflam- matory thickening of the membranes, which may originate in the lining membrane of the osseous system with which the nerv- ous structures come into contact; (1)) invasions of the neuro- glia by a diffuse form of gummatous infiltration, which may be the result, primarily, of disease of the circulatory system; and (c) the appearance of syphilomatous masses, usually located in the upper convolutions of the anterior lobes, and almost invariably at the cortex, closely united to the membranes, extending into the surrounding tissue, which is generally softened, hypervascular and of a faint yellow color; the nerve cells and vessels giving evidence, under the microscope, of degenerations resulting from vascular obstruction. _ Clinical Experience.—The cardinal treatment for cerebral syphilis, as for syphilitic diseases generally, is Jllercurius and Kali iod., in large doses. It is no use to speculate as to their homoeopathicity, or anything of that sort; the fact stands out prominently in the experience of every school that the best and most reliable remedies for syphilitic affections, whatever CEREBRAL SYPHILIS. 47 may be their seat, character, form or history, are large and frequently repeated doses of these two remedies. It is useless, therefore, and often worse than useless, to waste time in seeking other remedies for this disease in any given case until these have been fairly tried and failed. If experience is worth anything as a guide to treatment, we have it here. Therapeutic Indications.—Mercurius.—This is our sheet- anchor in the secondary forms of cerebral syphilis, that is, when associated, as is sometimes the case, with syphilitic exanthems, or other varieties of secondary syphilitic manifes- tations; mental and bodily anguish, with great restlessness and complete insomnia; pain deep in the head, setting the patient almost crazy; wishes he was dead. Kali i0d.——Best and most reliable remedy for the tertiary form of the disease, or when there are no other symptoms of the disease present than what is manifested in and by the nervous system; also in cases where mercury has been given injudiciously, or without curative effect; irresistible desire to go into the open air; torturing feeling of anguish, preventing sleep. Aurum.—After abuse of mercury and iodide of potassium; deep, tearing pains in the head; pains pressing from above downward and from within outward; great mental depression, with suicidal tendency. Cinnabaris.—-Most useful where there is a scrofulous state of the system coe'rcisting; also when complicated with scrofulosis and previous mercurialization combined. Berberis.—Tertiary form of the disease; tearing pains in the _ whole head, slightly ameliorated by going into the open air; head feels swollen and bloated ; disposition to weep. Silicea.—Gases complicated with scrofula; head feels as if it was teeming with living things; pains much aggravated at night; swelling of the superficial glands. Consult, also, the following remedies: Nitric ac., Lyce- podium, Phytolacca, Stillingia, Kali bich., Mezereum, Corydalis, Arsenicum iod., Mercurius nitrosus and corrosivus, Staphisagria, Hecla lava, Argentum nit., Sarsaparilla. Auxiliary Treatment.,—-This consists chiefly in endeavor- ing to palliate the symptoms caused by cerebral hypereemia and cerebral tumors, which see. 48 NERvoUs THERAPEUTICS. CEREBRAL TUMORS. Syn0nymS.—Tumors of the Brain; Fr., _Tumeurs du Cerveau; Ger, Hirngeschwttlste, Geschwttlste des Gehirns. Definition.—A swelling in the brain caused by some form of new growth. Diag‘n0sis.—Cerebral tumors are sometimes of easy recog- nition; at others it is impossible to diagnose them with any degree of certainty. Persistent headache, vomiting, double optic neuritis and frequent epileptic attacks are among the more common and prominent symptoms, and when they are all present in any case we are justified, in the absence of the dis- tinguishing signs of some other form of intracranial lesion, in referring the morbid phenomena to cerebral tumor. VV here the other symptoms correspond, very limited paralysis points to this cause; and so, also, do epileptic convulsions occurring late in life, especially if unilateral, or unattended with loss of consciousness. Certain characteristic symptoms will often serve to locate the tumor with considerable accuracy. Thus, when seated in the convexity there are epileptic spasms with severe headache, but no anaesthesia or paralysis. When the anterior lobes are concerned, there are frontal headache, anosmia and more or less mental disturbance. When one of the parietal lobes is in- volved there is anaesthesia, with slight unilateral paralysis. Tumors of the corpus striatum produce hemiplegia; of the corpora quadrigemina, ocular paralysis, blindness and hemi- plegia; of the area near the optic chiasm, headache, anosmia, hemiopia, paralysis of the ocular muscles, and anaesthesia of the parts supplied by the fifth nerve. When the cerebellum is implicated, the symptoms are occipital headache, vertigo and tottering gait. Tumors of the pons produce paralysis of the muscles supplied by the third, fifth and sixth nerves, difficulty of swallowing and crossed paralysis of the limbs. Tumors of the medulla oblongata produce convulsions, anaes- thesia, defective articulation, difficulty in swallowing, diabetes mellitus and paralysis of the bladder. Pathology:-Tumors of the brain have been classified as CEREBRAL TUMORS. 49 follows: (1) The diathetic, or cancerous, tuberculous and syphi- litic; (2) the parasitic, or those caused by the echinococcus (hydatids) and those produced by the cysticercus; (3) the vas- cular, or aneurismal; and (4) the accidental, which include the fibro-plastic, gliomatous, cholesteatomatous, osseous, enchon- dromatous, mucous, lipomatous, melanotic and other less important varieties. The pressure produced by cerebral tumors on the brain substance not only causes local symptoms, but not infrequently leads to fatty degeneration and atrophy of remote parts. It also causes displacement of the parts in the immediate vicinity of the tumor, renders the cerebral tissue dry and anaemic, and causes more or less atrophy of the nervous structure. Clinical Experience.——Marked relief has been obtained, in a number of cases, by the administration of Calc. carb., Graph, Sepia, Bell., Arn., Conium, Bry., Kali carb. and Bar. carb. Calcarea has proven most useful in atheromatous, fibrous and lipomatous forms; Graphites and Baryta carb. in the atheroma- tous and lipomatous; Sepia iii the fungoid and cancerous; Belladonna and Kali carb. in the fibrous; Arnica in the haema- tomatous; Conium in the fibroid and fibro-scirrhous. Therapeutic Indicati0nS.——Tumors not only produce by pressure the symptoms of sclerosis, but they cause anaemia, hyperaemia, hamorrhage, inflammation, softening, epilepsy, paralysis and atrophy. According, therefore, as the symptoms in any particular case correspond with one or more of these conditions, the remedies should be selected agreeably to the therapeutic indications given thereunder. Auxiliary Treatment.—Litt1e can be done in these cases, in the way of accessory treatment, except to aid in restoring the contractility of the paralyzed muscles by the induced gal- vanic current. A moderately weak current is generally to be preferred, and in no case should it be strong enough to cause much pain. The wet sponge of one electrode should be placed upon the paralyzed muscle and the other held in the patient’s hand, or applied to the nape of his neck, for a few minutes every day or two. In no case should the current be allowed to traverse the region of the tumor. 50 NERVOUS THERAPEUTICS. CEREBRAL CONCUSSICN. SynonymS.——Concussion of the Brain, Commotio Cerebralis; Fr., Corn/motion du Cerreau; Ger., Erschiitterung des Gehirns. Definition.—A shock or jar given to the nervous elements of the brain, whereby its functions are temporarily suspended, and the vital power more or less depressed. Diagnosis.—The diagnosis is generally easily made, as more or less external injury, the result of a fall or blow, is usually associated with it. It may, however, be mistaken for compression, unless the symptoms are carefully compared, as in the following table: Cerebral Concussion. Cerebral Compression. Not always so. Insensibility complete. Development sudden. Can usually be roused if loudly spoken IO. Respiration sighing, slow, irregular. Pulse soft, feeble, fluttering, intermit- l I I l . 1 Respiration stertorous, slow. I tent. ) I l a Pulse slow. No vomiting. Urine and faeces retained. Pupils insensible to light. Paralysis usually hemiplegic. Frequent vomiting. Urine and faeces passed involuntarily. Pupils react. Paralysis usually none; if present, gen- I erally of one or more cranial nerves. Pathology.—The effects produced by concussion are gener- ally the result of simple shock, the character of the injury being such as to temporarily depress the vital power, and in some cases to result in death. That this is always the case where no lesion is discoverable after death, cannot, of course, be proven, because a minute haemorrhage or other injury at some vital point, as, for example, at the internal origin of the pneumogastric nerve, would no doubt be sufficient to produce speedy death; but it is more reasonable to refer the fatal issue in these cases to shock alone than to causes which may have no existence. Clinical Experience.—- Glonoin, Arnica and Carnphora are usually the first remedies prescribed in these cases, Aconite CEREBRAL cououssrou. 51 being given in alternation with them to moderate reaction and to prevent inflammation. After reaction is established, if attended with cerebral disturbances, Belladonna, Hyoscyamus or Stramonium is usually given, as may be indicated. Opium and Laurocerasus are sometimes used, in cases where there is great depression, stertor and tendency to collapse. Therapeutic Indications:-—Glonoin.—Reactive power feeble and of slow development; pulse weak; surface cold but not clammy. Arnica.—-An excellent remedy for injuries of the brain at- tended by insensibility and unconsciousness; if fever super- venes, alternate with Aconite. Gamph0ra.——During the first stage, to promote reaction; sur- face cold and clammy; face pale; muscular twitchings. Gic11ta.—First stage, insensibility profound; face cold and deadly pale; cold hands, feet and limbs; inability to swallow; great depression of the vital power; delirium; convulsions. Hypericum.—-Second stage, with frequent pulse, swollen face, short breathing and tendency to start, with shuddering over the whole body. BeIlad0nna.——Second stage, when attended by excessive reac- tion; headache, flushed face and delirium; if fever is high, alternate with Aconite. Hyoscyamus.-—Second stage, attended by low, furious delirium. Ge1semium.—- wmains stupid and drowsy after slow reaction; pain in back of the head, pupils still dilated; paralysis of the lower sphincters. ' Lal1r0ceras11S.—Slow, feeble pulse; sunken countenance; skin cold and blue; audible breathing, with moaning; trembling of the limbs; involuntary discharge of fmces. Vipera.—Pulse slow. feeble and irregular; ‘surface cold and covered with cold perspiration; difficulty of swallowing; hemi- plegia, or paralysis of a single limb; vomiting; delirium. Lacl1esis.—Apoplectic symptoms, with low, muttering delirium, pale face, cold extremities; paralysis of the left side. Gonium.-—Apoplectic symptoms, slow, weak pulse; dilated pupils; tendency to collapse; trembling of the li1nbs; delirium, convulsions, numbness, paralysis. 52 NERvoUs THERAPEUTICS. Auxiliary Treatment.—-Brandy internally, or Amyl nit. by inhalation, is among the speediest means of overcoming the depression of the vital power, but care should be taken not to overstimulate the circulation, the aim being simply to reestablish the normal condition. In most cases it is only necessary to wrap the patient in warm blankets, apply friction to the surface, and use dry heat to the extremities. As soon as reaction sets in, the case is one for medical treatment only, no other form of stimulation being appropriate. SUN STR OKE. Syn0nyms.—Insolation, Insolatio, Heatstroke, Thermic Fever; Fr., Coup de Soleil; Ger., So-nnenstich. Definiti0n.—Various syncopal, asphyxial and hyperpy- rexial conditions, resulting from exposure to solar or artificial heat. Diagn0SiS.——The appearance of the patient, taken in con- nection with the history of the case, is usually sufficient to establish the diagnosis. By comparing the symptoms with those given in the table on page 50, it may be easily distin- guished from concussion and compression, with which alone it is liable to be confounded. Patho1ogy.—-In rapidly fatal cases the brain and its mem- branes, and also the lungs, are but slightly congested; the greatest changes are observed in the venous trunks, especially those of the abdomen, the right side of the heart and the pul- monary vessels, all of which are sometimes engorged with dark, grumous blood, while patches of ecchymoses are also scattered over the surface of the body. These appearances are chiefly due to nervous shock, which, by paralyzing the heart and lungs, leaves the venous system engorged with blood. In thermic cases a similar condition often exists, to- gether with a more or less congested state of the brain and its membranes. This condition is the result of heat on the nerve- centres, and through them on the vaso-motor nerves. As a consequence, the nerve-centres generally, and especially the respiratory, suffer from overstimulation, and this is followed by exhaustion. SUNSTROKE. 53 Clinical Experience. — Glonoin, Arnica, Camphora, Amyl nit, Gelsemium, Belladonna, Veratrum vir., Lachesis, Scutellaria, Cactus and Carbo veg. are the principal remedies relied upon in the treatment of sunstroke. Therapeutic Indications.--Glonoin.--After reaction has set in, or when there is intense headache, with throbbing in all parts of the head ; painful constriction of the heart; sensation as if all the blood had gone to the head; fainty feeling, with complete muscular relaxation; oppression of breathing, with numbness of the limbs. Especially adapted to the thermic and syncopal forms. Amyl nit.—Violent determination of blood to the head and face; violent beating of the cervical and temporal arteries; great difficulty of breathing. Camphora.——-Great depression of both the nervous and circu- latory systems; coldness of the body; tremors and cramps; oppression of breathing; syncopal form. Belladonna.——Indicated when apoplectic or irritative symp- toms exist, such as coma, stertorous breathing, headache, vertigo, delirium, rsensitiveness to light and sound, etc. Antimonium crud.-—Syncopal form, with fainting, nausea, vomiting, etc. . Carbo Veg.—Extreme prostration of the vital power; heat exhaustion. Aconite.--Thermic form; burning heat, especially in the head and face; heat and dryness of the skin, with thirst, head- ache, redness of the eyes, anxiety and difficulty of breathing. Veratrum vir.—Congestion to the head and chest; gastric disturbances, especially vomiting; fainting, with coldness of the limbs. Useful in both the ther1nic and syncopal forms of sunstroke. Stmtellaria.—Great fulness and oppression of the head, with flushed face; oppression of the chest, with throbbing about the heart; general uneasiness, with twitching of the muscles; sticking pains in various parts of the body. Arnica.-—Often the only remedy required, especially in the syncopal form ; also useful where there is great depression of the vital power, with coldness of the limbs, stupor and semi- paralysis. 54 NERVOUS THERAPEUTICS. Digitalis.-—-Cardiac weakness, with great prostration and tendency to syncope from heat-exhaustion. Auxiliary Treatment.——In ordinary cases of sunstroke, arising from long exposure to the direct rays of the sun, or where the temperature is far above the normal standard, the burning heat of the surface should be reduced as quickly as possible by the free application of the cold water douche, ice and ice-water to the head and neck, cool air, fanning, etc., being careful at the same time not to use the ice or the douche too long, or after the skin becomes cool. On the other hand, these measures should_never be adopted if the skin be cold and clammy and the respiration sighing. The syncopal form, arising from heat-exhaustion, requires precisely the opposite treatment. In these cases there is an entire absence of fever, the pulse is soft and compressible and the skin cool. The indications here may be met by lowering the head and giving the patient small and frequent quantities of hot beef-tea, store tea, coca, etc. This condition calls for Digitalis rather than alcohol, the remedy usually administered. For further in- formation on this subject, see the author’s work on Intracranial Diseases, p. 294. CEREBRAL PARALYSIS. Synonyms.——-Paralysis of Cerebral Origin, Common Palsy, Hemiplegia; Fr., Paralysie Ce’re’brale; Gen, Gehirnla'hmung. Definition.—-Loss of the power of voluntarily exciting the contraction of muscles on one side of the body, caused by dis- ease of the brain. Diagnosis.—-Cerebral paralysis may generally be distin- guished from paralysis of spinal origin by its being confined to one lateral half of the body. When complete, as in most cases of cerebral haemorrhage and other varieties of apoplexy, it usually takes the form of hemiplegia. Very rarely the paralysis, instead of being unilateral, is bilateral; but then it occurs as two separate hemiplegiae, not as a paraplegia, one side being more severely affected than the other. Not infre- quently the paralysis is limited to the parts supplied by par- ticular nerves and plexuses. Cerebral symptoms, more or less CEREBRAL PARALYSIS. 55 conspicuous, are almost invariably present, such as those which characterize cerebral haemorrhage, thrombosis, embo- lism, tumors, etc., these being the principal causes of the paral- ysis. Motor irritation, in the forms of muscular spasm, twitch- ing and contraction, is common in the affected parts, and so also are epileptiform convulsions; but reflex movements are commonly preserved, and even increased in energy, while automatic and associated movements remain, as a rule, unaltered. Path0l0gy.——Encephalic lesions, of various kinds, constitute the ‘gross pathological condition in cerebral paralysis. These lesions are numerous and varied, comprising haemorrhage, vascular obstruction, inflammation, softening, tumors, etc. They give rise to certain characteristic symptoms, according to the particular part affected. Thus paralysis arising from lesions of the cortex takes the form of monoplegias, partial hemiplegias, paralyses of the glossal, facial and brachial nerves, or of the nerves of the face and arm, or arm and leg. Lesions implicating the region of the basal ganglia, if exten- sive, produce hemiplegia and cerebral hemianaesthesia. When the region of the left middle cerebral artery is invaded we usually have aphasia. Cerebellar disease produces incoiirdi- nation and a titubating gait. A peculiar form of alternate paralysis is produced by lesions in the lower and inner part of the crus cerebri, and in the lower lateral half of the pons. In the former case, the motor-oculi nerve is paralyzed on the side of the lesion, and at the same time there is a hemiplegic condition of the opposite side of the face and body; in the latter, a paralysis of the face on the side of the lesion, and more or less paralysis of the trunk and limbs on the opposite side. Lesions of the medulla oblongata, in addition to paral- ysis, give rise to respiratory and circulatory disturbances, aphonia, dysphagia, anaesthesia, dysaesthesia, etc., from impli- cation of nerve roots arising from it. Atrophy of the muscles seldom occurs in connection with cerebral paralysis except in disease of the pons. The therapeutic indications pertaining to cerebral paral- ysis are given under the several diseases of which the paralysis 56 NERVOUS THERAPEUTICS. Initial stage. is a symptom, especially cerebral haemorrhage. See, also, infantile cerebral paralysis and progressive general paralysis. INFANTILE CEREBRAL PARALYSIS. Syn0nyms.——Poliencepalitis Aouta, Hemiplegia Cerebralis, Spastica; Fr., Paralysie Cérébrale de l’Enfance ; G’er., Kinder- ltihmung des Gehirns. Definition.—A peculiar form of infantile paralysis, of en- cephalic origin, usually hemiplegic, and commonly attended by athetosis, epilepsy and impaired intellect. Diagn0sis.——The disease is most liable to be mistaken for infantile spinal paralysis, from which it may be differentiated by means of the following table: Infantile Spinal Paralysis. Cerebral Paralysis. I I Fever, convulsions, loss of con- sciousness. These may all ’ fail, and this stage be un- ; noticed. I Paralysis usually begins 1——4, seldom later. i Monoplegias and paraplegias, Ii seldom hemiplegias. Age. Paralysis. The nature of the l Muscles “flail-like,” contract- The same. Generally under 4, may occur immediately after birth. Hemiplegias commonest, mon- oplegias sometimes, para- plegia rare. paralysis. ures form after long time. E l e c t r i c r e a c- Faradaism strongly reduced. tions. ( R. D. obtained. Sensation. : Unchanged. Tendon reflexes. I Lost. Temperature and 1 Lowered, and limbs look livid color of limbs. and feel cold. I n h i b i t io n of Strongly marked. growth. 1 Motor affections. I Not present. Intelligence. Unaffected. Bladder and rec- f Not affected. tum. i Paretic contract- I Pgs varus, ll and COm_ ures. ‘ C‘ val us . . g ’ blnations of calcaneous, th , , ese. 1 equinus, Slight contractures form early, recovery is constant. F aradaism retained, no R. D. Scarcely changed. Exaggerated. Temperature not lowered, limbs of normal color and warmth. Not so marked, generally mostly so in upper limb. Athetosis and epilepsy. Often lost. Now and then slightly affected. Generally nothing except equ- inus spasticus, and con- traction of knee. INFAN TILE CEREBRAL PARALYSIS. Pathology.—-The motor gray matter of the cerebral cortex is the seat of an inflammatory process, pathologically resem- bling that found in acute spinal paralysis, leading to perma- nent loss of function of the part, due to subsequent atrophy and destruction of the affected area. Clinical Experience.—I can find no well-defined homoeo- pathic clinical experience recorded concerning this newly- described disease; but as it is of a similar nature to infantile spinal paralysis, and as cerebral cases of what have heretofore been regarded as cases of that disease have occasionally been described under the name of the “essential paralysis of child- hood,” we are justified, I think, in regarding the clinical his- tory of such cases as belonging to this affection. This gives us Stannum, Gelsemium, Arnica and Belladonna as being reme- dies of marked value in this disease. Therapeutic Indications.—Stannum.-—Paralyzed parts con- stantly moist from perspiration; paralysis of the left side; pain, accompanied with a sense of faintness in the brain. Gelsemium.—-Loss of will-power over the muscles; pain in the top and back of the head, with stupor, verging to coma; con- vulsions, followed by paralysis. Belladonna.-—‘-Paralysis of the right side; great restlessness, with sudden startings; congestion and irritation of the brain. Arnica.—Cerebral inflammation, followed by evudation; the child cannot bear to have its head moved, owing to soreness of the brain. Consult, also, the indications given under acute hydrocephalus, progressive general paralysis and infantile spinal paralysis. Auxiliary Treatment.—-Ice or ice-cold water applied to the head during the initial stage is useful, but at a later period cloths wrung out of hot water are more serviceable. Great care should be taken to keep the lower extremities, and especially the paralyzed parts, warm. At a later stage, moral treat- ment may be necessary, in consequence of the dementia, especially as regards cleanliness, the imitative faculty being trained for this purpose. 58 NERVOUS THERAPEUTICS. EXTERNAL CEREBRAL PACHYMENINGITIS. Synonyms.—Traumatic Cerebral Pachymeningitis, Second- ary Pachymeningitis, Pachymeningitis Acuta; Fr., Pachymen- ingite Secondaire; Ger., Seconddre Pachymeningite. Definition.——InflammatiOn of the external layer of the dura mater, usually acute, but sometimes chronic, secondary to inflammation of the adjacent bone, and commonly due to injury of the head. Diagnosis.—This affection cannot be diagnosed with cer- tainty, but fever, severe headache and stupidity, coming on soon after an injury to the head, point to its existence. The diagnosis is confirmed if symptoms of pyaemia supervene, this being a very common complication in these cases. Pathology.——Both the pachymeningitis and the pyaemia, when present, are due to inflammation of the bone. The pyaemic infection is caused by the decomposing material from the seat of injury finding its way into the circulation through the veins of the diploe, which become inflamed in conjunction with the gangrenous osteitis. Clinical Experience.-—-Arnica, Hypericum, Belladonna and Aconite are usually prescribed in traumatic cases as soon as inflammatory symptoms appear, the two latter generally in alternation, after Arnica or Hypericum has been given. Mer- curius and Kali iod. are usually given when the symptoms seem to depend upon syphilis or when the case has a syph- ilitic history. Gelsemimn and Opium are resorted to when there is much stupor. Chin. sulph. and Arsenicum are usually preferred after toxaemia and adynamia make their appearance, Calendula being sometimes previously given to prevent suppu- ration. Eucalyptus and Salicylic ac. are also sometimes given as antiseptic remedies. Therapeutic Indications.——-These are similar to those given ‘under the head of simple acute meningitis, which see. Auxiliary Treatment.——External pachymeningitis is, at the outset, a purely surgical disease, and demands surgical treatment. After carefully cleaning the wound, if the bone is depressed the trephine should be at once applied, so as to INTERNAL CEREBRAL PAC/HYMENINGITIS. prevent the supervention of meningitis, by elevating the bone, removing detached fragments, if any, and allowing a free escape of the secretions. A dressing of charpie, or of borated cotton, saturated with Calendula or Hypericum lotion, should then be applied, and this should be kept constantly moistened. The diet should be nutritious and easily digestible, but not stimulating. INTERNAL CEREBRAL PAGHYMENINGITIS. Synonyms.—-Cerebral Meningeal Haemorrhage, Haemor- rhagic Pachymeningitis, Chronic Pachymeningitis, Haematoma Durae Matris ; Fr., Hémorrhagie des Méninges, Hémorrhagie Men- ingée Cérébrale, Apoplexie Méningée; Ger., Hirnhautblutungen. Definition.--A peculiar form of meningeal haemorrhage, the result of chronic inflammation of the dura mater, in which the effused blood is collected in sacs formed of false membrane. Diagnosis.—A constant and very severe headache, with a gradually increasing tendency to stupor, slow and irregular pulse, contracted pupils, but unattended by facial paralysis, convulsions, fever or vomiting,-is regarded by Jaccoud and others as suflicient to indicate the existence of this form of meningeal haemorrhage. Path0l0g‘y.—Extra and intra-meningeal heemorrhages are almost always the result of direct injury, such as is produced by wounds, trephining, etc. ; but haematoma of the dura mater is the result of chronic pachymeningitis, and is met with under the dura mater, in the form of oval sacs, sometimes several inches in diameter, and half an inch or so in thickness. They are generally seated near the sagittal suture, and extend to both hemispheres, with only the arachnoid and pia mater between. The contained blood is either in a liquid or a co- agulated condition, and, as in other sanguineous collections, exhibits in different cases similar stages of degeneration. Clinical Experience.—This does not materially differ from what is given under this head in cerebral hyperaernia, haemor- rhage and tumors, which see. Therapeutic Indicati0ns.—Identical with those given in 60 NERvoUs THERAPEUTICS. treating of the above-named diseases, and to which reference should be made. Auxiliary Treatment.—-The great mental and bodily in- firmity which sooner or later overtakes the patient may be palliated, and its development retarded, by such hygienic measures as are calculated to invigorate the system, such as fresh air, good, nutritious food, agreeable company, etc. CEREBRAL ARACHNITIS. Synonyms.—-Inflammation of the Arachnoid Membrane of the Brain, Traumatic Arachnitis; Fr., Inflammation dc l’Arach- noide; Gen, Entzilndung der Arachnoidea. ‘ Definition.-——Inflammation of the cerebral arachnoid mem- brane, due in most cases to injury of the head. Diagnosis.——If the evidences of arachnitis are widely dif- fused over one of the hemispheres, and are at the same time accompanied by hemiplegia of the opposite limbs, the hemi- plegia involving both sensation and motion, we may safely conclude that the case is one of true cerebral arachnitis. Pathology.-The possibility of the existence of cerebral arachnitis has been called in question on the grounds that the so-called parietal layer of the arachnoid does not exist, while the inflammation of the visceral layer never occurs without simultaneous inflammation of the pia mater; but this opinion is successfully controverted by the fact that in cerebral arach- nitis an even layer of purulent lymph is found to cover the cerebral convolutions without dipping into the sulci, being prevented by the intervening arachnoid membrane, which stretches across instead of entering the cerebral depressions; whereas, when the subarachnoid spaces are involved, the sulci are filled with lymph, and the internal surface of the arach- - noid remains free and unaffected. Clinical Experience.—This is the same as in inflammation of the adjacent I-nembranes——Aconite, Belladonna, Apis, Bryonia, Mercurius, Kali iod. and Sulphur being given according to the special indications. Therapeutic Indications.—These do not materially differ TRAUMATIC CEREBRAL LEPTOMENINGITIS. ' 61 from those given under the head of simple cerebral meningitis, which see. Auxiliary Treatment.--—Traumatic cases require surgical treatment, similar to that given under the head of external cere- bral pachymeningitis, to which reference should be made. Idio- pathic‘ cases, which are comparatively rare, are usually com- plicated with simple .cerebral meningitis, and therefore the accessory treatment recommended thereunder will be appro- priate. TRAUMATIC CEREBRAL LEPTOMENINGITIS. Synonyms.-—Traumatic Inflammation of the Pia Mater of the Brain, Subarachnoid Meningitis, Leptomeningitis Cere- bralis; Fr., Méningite Consecutifs e la Carie du Rocher; Ger., Seconddre Leptomeningite, Aleute Conneasitdts Meningitis. DefinitiOn.——An inflammation of the pia mater of the brain, involving primarily the areolar tissue of the subarachnoidean spaces, usually due to some injury implicating the base of the skull. Diagnosis.—-The disease may be suspected when, after sup- posed injury of the base of the skull, vague cerebral symptoms, unattended by decided paralysis, make their appearance; and if the petrous bone has been fractured, as shown by bleeding from the ear and deafness, with facial paralysis in the first place, then the existence of this form of meningitis may be regarded as reasonably certain. Path0l0gy.—The inflammation is supposed to gain access to the subarachnoid spaces by traveling along the trunk of the seventh nerve, and afterward spreading upward through the posterior fissures to the ventricles, or over the surface of the hemispheres, or else downward on the medulla oblongata and its connections. The subarachnoidean inflammation may, however, result from the admission of air through the fracture, either by way of the external meatus or the Eustachian tube, for the fracture, instead of being a simple one, is actually coml pound. Indeed, it is highly probable that this is the true explanation, as the admission of air into wounds, especially 62 NERVOUS THERAPEUTICS. suppurating ones, not only greatly changes the character of the inflammation, but contaminates the air itself, which may thereafter become the vehicle of its transfer to more distant parts. Clinical Experience.—Apis, Hypericum,Bryonia and Silicea have been given with good results in this form of leptomenin- gitis, though such cases, in the long run, almost always prove fatal. Apis and Bryonia are given to promote absorption of serous effusions, and Silicea to limit or prevent suppurative action. Therapeutic Ind.ications.—These are similar to those given under the head of simple cerebral meningitis, which see. Auxiliary Treatment.—-There is nothing very peculiar about this form of meningeal inflammation, except so far as its surgical features are concerned. Should the discharge from the ear become purulent-—which, if the patient lives, it is almost certain to do—great care should be taken to insure its free and uninterrupted evacuation, and for this purpose I have usually found nothing better than warm fomentations, or the steam from a steam atomizer, applied to the aural region, whenever the flow becomes suddenly interrupted or the patient suddenly comatose. SIMPLE ACUTE CEREBRAL MENINGITIS. Synonyms:-—Meningitis, Cerebral Meningitis, Simple Cere- bral Meningitis, Idiopathic Cerebral Leptomeningitis, Lepto- meningitis Cerebralis, Leptomeningitis Infantum, Hydro- cephalus Acutus sine Tuberculosis; Fr, Méningite Simple ; Ger, Allgemeine Alcute Ifirnhautentzlindung. Definition.—A simple acute inflammation of the pia mater of the brain. Diagnosis.--Simple cerebral meningitis is most liable to be mistaken for the tubercular form of the disease, especially when it involves the base of the brain. The following table gives the differential diagnosis between them: SI.\I P LE ACUTE CEREBRAL MENINGITIS. 63 Tubercular Meningitis. l r I Simple Basilar Meningitis. Onset gradual. Temperature 102° to 103°, not continu- ous but very irregular, falling some- times for a day or so down to normal, or nearly so. Pulse compressible, rapid, and, after first week, intermitting, losing occa- sionally a beat. Face looks usually pale. Eyes not injected; squinting toward end of disease; pupils uncertain, later dilated. Tongue slightly coated. Vomiting ‘frequently in the beginning; will appear by itself, not only after eating; ceases generally when con- vulsions begin, toward latter part of disease. Bowels very constipated. Cough harassing and obstinate; gen- erally physical signs of tubercular deposits in the apices. Convulsions appear at beginning of about last third of the ailment; may continue for one or more weeks, gradually increasing in number and severity as death approaches. I l l i l I l Duration about three weeks; may be ‘ much longer. Prognosis: invariably fatal. Post-mortem appearances: deposits of small tubercular bodies, mainly at the base of the brain; signs of in- flammation of membranes, effusion of fluid and formation of lymph; deposits in other parts of the body. Beginning most abrupt. Temperature 102° to 103%° ; continues at that height throughout the dis- ease; never sudden and great changes. Pulse rapid and somewhat tense; always regular, except, perhaps, during agony of death. Face flushed. Eyes always injected, occasionally squinting; eyes apt to be very sensi- tive to light; pupils often con- tracted. Tongue red. Vomiting generally first symptom, and continues to the last; happens only immediately after eating. Bowels not constipated; there is often diarrhoea. Cough mild; mostly due to bronchial irritation ; percussion clear. Convulsions immediately before death, never continuing longer than a day, or at most two, followed by a comatose condition. Duration less than a week; sometimes only two to four days; never longer than seven. Prognosis: grave, but not necessarily fatal. Post-mortem appearances: never any granular deposits; signs of inflam- mation of arachnoid and pia mater, often severe, especially at the base; associated with abundant effusion and copious accumulation of lymph. Pathology.—It is generally supposed that no gross patho- 64 NERvoUs THERAPEUTICS. logical changes involving the pia mater are discoverable after death by this disease; but this is not, strictly speak- ing, correct. Abnormalties are found, according to the stage of the disease, consisting either of a gelatinous white or yellow lymph-like matter, puriform, or else in the form of membranous layers. They are generally limited to the convexity, but some- times they involve both the lateral regions and the base of the brain. The inflammation is not always confined to the pia mater, but sometimes implicates the adjacent tissues, in which case we have a meningo-cerebritis, of variable seat and extent. Clinical Experience.-——The remedies most commonly em- ployed in simple meningitis are: Aconite during the initial stage, with high fever, delirium, etc., followed by Belladonna, Atrophine 35c, Hyoscyamus, Stramonium or Bryonia, as the delirium,pains, etc.,become more pronounced and severe. Apis, Helleborus, Bryonia, and sometimes Opium are given when there are much depression and stupor, indicating effusion, or when there are low muttering delirium, coldness of the ex- tremities, etc. Zincum and Zincum brom. have proved beneficial in advanced cases, even after paralysis has supervened. Therapeutic Indications.—Aconite.-—At the outset of the disease, or when there is high fever, with dry, burning heat of the skin, red inflamed eyes, pulse full and hard, pupils con- tracted and burning, throbbing or lancinating pains in and through the whole head; anxiety or great anguish; delirium; vomiting of bile; convulsions; spasmodic contractions; pa- ralysis. Belladonna.—Face and skin red, burning and swollen; red and sparkling eyes; lancinating, stinging or burning headache; delirium, with frequent vomiting; pulse small and quick, or intermittent; insensibility, spasms and paralysis. Hy0scyamus.—Delirium, gradually passing into stupor and coma; red, burning face, red and sparkling eyes, con- tracted pupils, strong and quick pulse, sticking pains in the head; wild delirium, the patient singing, muttering, smiling, talking wildly; starting suddenly; picking at the bed-clothes, with loss of consciousness, dilated pupils, cold and pale face, weak and intermitting pulse and paralysis. SIMPLE ACUTE CEREBRAL MENINGITIS. Digitalis.——Stupor, gradually deepening into coma; irregu- la-r action of the heart, sometimes very weak, at others strong; small and slow pulse; dilated pupils, with insensibility of vision; general or partial convulsions; especially suited to the last stage, or stage of depression. Apis Inel.—Infantile cases, with delirium, loss of conscious- ness and occasional shrill screams; bending back and rolling of the head; squinting of the eyes; child puts its hand to its head while it screams, even when unconscious; face pale, or marked with red streaks or spots; scanty or suppressed urine; very frequent and weak pulse, or else slow and irregular; con- vulsions, trembling of the limbs and paralysis. Secondary meningitis from suppressed erysipelas or other exanthem. Stramonium.—Violent delirium, accompanied by frightful screams ; opisthotonos; vomiting; red face, with thirst and great dryness of the mouth; convulsive movements of the limbs; moaning and tossing about; staring look, especially on waking; feverish heat, moist skin; sleep almost natural, but on being aroused patient does not recognize his friends; retention of urine. Cuprum.--Head hot, with sharp, lancinating pains shooting through it; red, inflamed and rolling eyes, with delirium or stupor; quick, strong pulse, with more or less vomiting; tonic spasms and convulsions; suited also to the last stage, attended with slow, small and weak pulse, blue, shrunken face, dimness of vision, moist hands and paralysis; specially adapted to cases in which there is irritation of the spinal cord. Bryonia.—-During the first stage, with sharp, shooting pains in the head, especially through the temples, red and inflamed eyes, hot and burning skin, delirium, cramps, etc.; also, at a later period, when the disease is verging into that of depression, with stupor, dim and glossy eyes, slow and irregular pulse, cold, pale, moist skin, dry and brownish tongue; also when the patient bends the head backward, constantly works the jaws, or starts suddenly from sleep, screaming, with cold sweat on the forehead. Glonoin.-—Intense headache, with throbbing of the temporal arteries, red face, full and rapid pulse, hot and staring eyes, 66 mmvous THERAPEUTICS. ringing in the ears and vomiting; brain feels too large for the skull; globe of the eye feels sore; irregular pulse, with moist skin. Suited to every stage of the complaint. Gelsemium.——Child drowsy and wants to be let alone; fre- quent startings in sleep; bores its head backward into the pillow; constant fever, though without much thirst; head hot, but the hands and feet cool and moist; nausea, with blindness; espe- cially suited to children teething. Cimioifuga. — Pain in and behind the eyeballs, extending through to the occiput; tongue clean, but pointed and trem- bling; pain increased by movement of the eyes; soreness and stiflness of the muscles; excruciating pains in the head, increased by movement; delirium, with incessant talking. Helleborus.——Head drawn back, with stiffness of the cervical muscles; eyes staring and oblique; forehead contracted and cov- ered with perspiration; frequent starting and screaming during sleep; working of the jaws; breathing irregular, sometimes quick, at others slow and deep, or sighing ; jerking of the limbs, with convulsive movements of individual muscles. Opium.-—-Stupor and insensibility, with stertorous breathing, dilated pupils, half-open eyes, small, weak, irregular pulse and suppressed urine; when aroused, patient relapses immediately into a state of insensibility. Ethusa cyn.—Obstinate vomiting; pupils dilated and in- sensible to light; coma, with cold skin, pale face and collapsed appearance; drawing in the back of the neck; tetanic convul- sions. Anacardium.—Sequlae of brain fever, with total loss of mem- ory; weakness of all the special senses; mental dulness and confusion ; incomplete paralysis of the voluntary muscles. Auxiliary Treatment.——During the active, inflammatory stage, marked by high fever and excitement, ice to the head is almost indispensable; at a later period, and especially during the stage of depression, cloths wrung out of hot water are more suitable. As the power to digest proteids is nearly, if not quite, abolished, and the secretion of saliva greatly diminished, only such articles as sweet whey, fruit decoctions, water gruel, etc., will be appropriate until the beginning of convalescence, TUBERCULAR CEREBRAL MENINGITIS. 67 when we may gradually administer more concentrated farina- cious preparations, milk, with malt extract, light broth or Liebig’s infant food. This cautious diet is necessary during the stage of convalescence, because, if complicated with fever, as it is apt to be from indigestion, the disturbance thus pro- duced is liable to retard the absorption of the exudation. TUBERCULAR CEREBRAL MENINGITIS. Synonyms. —— Tubercular Inflammation of the Cerebral Meninges, Granular Meningitis, Acute Hydrocephalus, Hy- drocephalus Internus, Tubercular Leptomeningitis; Fr., Fiévre Cérébrale, Méningite Tuberculeuse, Méningite Granuleuse; Ger., T uberculose Hirnhautentzitndung. , Definition.—An acute inflammation of the cerebral mem- branes, especially of the pia mater, at the base of the brain, complicated with, and dependent upon, a growth of tubercles in the brain and other parts of the body. Diagnosis.—The differential diagnosis between this disease and simple basilar meningitis is given under the latter head, which see. Typhoid fever, to which at times it bears a very close resemblance, may be distinguished from it by means of the following table: Tubercular Meningitis. Typhoid Fever. FIRST STAGE. There is a gradual loss of flesh, extend- l Loss of flesh only apparent after fever- ing over some weeks or months. I rritability more intense and prolonged; restless during sleep. Shunning light is common. Temperature has no characteristic change; may be high in the morn- ing and low in the evening, or the same morning and evening. Vomiting causeless, and not connected with ingesta. May find a clean tongue. process has existed some time. Irritability not so intense; quieter dur- ing sleep. Absent. Typical fever curve; gradual ascent, having low fever in the morning and higher in the evening. Vomiting nearly always connected with curdled milk or repugnant medi- cine. Coated tongue. 68 NERvoUs THERAPEUTICS. SEOOND STAGE. Headache not aggravated at any partic- ular time of the day. Nearly always constipation. N o abdominal tenderness. Pulse of good volume, moderately slow, and occasionally irregular. N o epistaxis. Headache always aggravated toward evening, when the fever ascends. Diarrhoea, as a rule; exceptionally, constipation. Abdominal tenderness and tympanitis. Pulse soft, rapid, and never irregular. Often epistaxis. THIRD OR ADVANCED STAGE. Irregular temperature curve or no fever at all. Now the vomiting generally ceases. Stupor is continual, patient not easily aroused, and immediately falls back again into his former state. Obstinate constipation. Retraction of abdomen. Tache cérébrale; sudden and spontane- ous blushing of check and of parts exposed to pressure. Cheyne-Stokes breathing. Pulse very irregular. Spleen normal. Local palsies and local spasms; fixed- ness of the eyes; unequal or di- lated pupil. Extreme tenderness elicited on press- ing the femur. Urohaematin, but no albumen or indi- can in the urine. Continued fever, stationary, or ascend- ing gradually with the morning re- mission. May have vomiting of ingesta. Is easily aroused; remains awake for a time and requests drink. Is usually rational during the time of being awake. Generally diarrhoea, yellow or brown- ish stools. Tympanitis and tender abdomen. Roseolar eruption. Breathing at times very irregular, quite sighing, but not the rhythmical ir- regularity. One day regular, and the next very irregular. Pulse weak and regular. Spleen enlarged and tender. N 0 such manifestations. No tenderness on pressure. Indican and albumen always present in the urine. Pathology.—The tubercular matter is mainly found along the course of the vessels of the pia mater, at the base of the brain, a fact which serves to explain the motor disturbances observed in this disease. Its ordinary seat is along the middle meningeal artery and its branches; but it is sometimes depos- ited, though rarely, on the convexity. The pia mater is always TUBERCULAR CEREBRAL MENINGITIS. 69 more or less inflamed, thickened, infiltrated, and covered with sero-plastic or purulent exudates. The ventricles are distended with serum, sometimes to the point of rupture. The tuber- cular matter is not confined to the brain, but is usually met with in other organs, especially the lungs. Clinical Experience.—Dr. Price, of Baltimore, thinks that he has cured at least four cases of this disease by means of Helleborus, Bryonia, Apis and Artemisia vulg. Other remedies which have been given with greater or less benefit in tuber- cular meningitis are: Cicuta, Veratrum alb., Argentum nit., Kali iod., Calcarea phos., Zincum, Belladonna, Spongia, Gelsemium and Gina. Therapeutic Indications.—Artemisia vulg.--Child lies in a sleepy or dreamy state, drinking freely of -water without being aroused; surface cold, left side paralyzed, right in a state of chronic convulsion; involuntary stools» Especially indicated in the last stage. Helleborus.-—-Soporose condition; forehead wrinkled and covered with cold perspiration; dilated pupils; involuntary throwing about of one arm or leg; lower jaw hangs down; paralysis of one side. Chiefly indicated in the last stage of the disease, or after paralysis has set in. Bry0nia.—Constant working of the jaws; lips dry and parched; the least motion produces fainting or nausea; constipa- tion; symptoms changing to those of depression. Indicated after eflusion has set in, and the system has become more or less depressed. Apis.—Stupor; constant motion of one arm or leg; urine scanty or ‘suppressed; involuntary stools, which are green, lumpy and slimy; pulse irregular; one side paralyzed, the other convulsed. Specially indicated after exudation has taken place. - Calcarea carb.—Lively, precocious, large-headed children, with tender constitutions, a swollen abdomen and irregular bowels, inclined to looseness; profuse perspiration during sleep; child screams out unexpectedly without cause. Espe- cially indicated during the prodromic or irritative stage. ' Galcarea phos.-—Scrofulous children, greatly emaciated, den- 70 NERVOUS THERAPEUTICS. tition retarded; stools loose and green, occasionally slimy; child feverish and always wanting to nurse; craves potatoes and other forms of starchy food; slow in learning to walk; face pale, or yellowish and sallow; looks stupid, and takes no interest in anything; fontanelles open. Scrofulous constitu- tions, both before and after tubercular disease has set in. Kali i0d.—Darting pains in the head, preventing sleep; pain and heat in the head, with red and burning face; epistaxis; drowsiness; dry and hacking cough; spasmodic muscular contraction; chilliness alternating with flashes of heat; hemi- plegia. Kafka advises the early use of this remedy before exudation has taken place as well as afterward, the remedy having acted favorably at both periods. Cina.—Irritative fever, with daily exacerbations, remitting after midnight; pallor about the nose and mouth; child bores into and picks its nose; constantly whining and moaning; cannot hear to be touched ; frequently dizzy, and occasionally loses consciousness. Prodromal symptoms. Belladonna.—Child lies in a drowsy or semicomatose state, from which it starts suddenly at times, but is never fully aroused; is dizzy when suddenly raised up, and not infre- quently vomits; opisthotonos; pupils dilated; cannot see any- thing that is transpiring in the room ; pupils dilated. Lyc0p0dium.—Somnolency, gradually deepening into coma; convulsions, either partial or general; child sleeps with half- open eyes; is very restless, throwing its head from side to side; moans and screams out in sleep; face pale and cold; neck stiff; body greatly emaciated; bowels costive. This is a highly important remedy in tubercular affections, especially when the head is involved. Spongia.—Redness of face, with anxious expression of coun- tenance; hyperaemia of the brain; bending of the head back- ward; face alternately red and pale; eyes staring, lids wide open; double vision; child frequently wakes with a start; muscular twitchings accompany the fever; somnolency and stupor. This remedy is highly recommended by Hering for this disease. Veratrum alb.—Great inequality in the distribution of heat; cnaoruc CEREBRAL MENINGITIS. 71 the least motion causes nausea or vomiting; neck stiff, with great tendency to convulsions; face pale, or one cheek pale and the other red; great prostration after stool; symptoms aggravated by raising the patient up; extreme thirst. Silicea.—-—Children with enlarged heads and slowly-closing fontanelles; heat and redness of the face, with cold extremi- ties; sweat about the head, face and neck; great drowsiness, but frequent startings during sleep; stomach easily sours; sour eructations, accompanied with nausea or vomiting. Auxiliary Treatment.-—Children predisposed to this dis- ease, by reason of having inherited a scrofulous or tubercular constitution, should be carefully guarded against those unhy- gienic influences which favor malnutrition, such as depriva- tion of fresh air, sunlight, wholesome food, and especially guarding against a diet that tends to induce functional de- rangement of the digestive organs. Even after the disease has set in, it is important to avoid all food that might increase the vomiting, and hence milk is to be omitted, giving Liebig’s or some similar infantile food instead. Where the coughing is so severe as to produce congestion of the brain, Dr. Price, whose success in the treatment of this disease is exceptional, advises the inhalation of the fumes of Cresoline, which he says mitigates the cough more than Drosera, or any other remedy. CHRONIC CEREBRAL MENINGITIS. Synonyms.—Chronic Meningitis, Chronic Basilar Menin- gitis, and Verticular vel Convexital Meningitis, Chronic Syphi- litic Meningitis; Fr., M éningite Cérébrale Chronigue; Ger., Chronische Hirnhautentzitndung. Diagn0Sis.—There being no broad distinction between these several varieties of chronic meningitis, except that which is based on the location or aetiology of the morbid process, I shall include them all under one head. The comparative mildness of the symptoms, no less than the chronicity of their course, will serve to distinguish the chronic from the acute forms; and when originating in the 72 NERvoUs THERAPEUTICS. latter, the previous history of the case will be sufficient to establish their nature. The softening resulting from cerebral thrombosis may be known both by the intensity of the symp- toms and by the nature of the cause producing it. Thus, while the pain is less in softening than it is in inflammation of the membranes, the mental symptoms are more severe, and vice versa. Chronic basilar meningitis may be distinguished from the convexital variety by the disturbances produced by implication of the cranial nerves, as one or another of them becomes involved in the inflammatory process. 0 Path0logy.—The thickening and opacity observed in most cases of chronic cerebral meningitis are believed to arise, in most cases, from Overstimulation, either syphilitic, alcoholic or mental. This is highly probable, since we know that these various forms of irritation are among the most common causes of chronic meningitis. By some, the changes above referred to are regarded as a mere result of degenerative overgrowth, brought about partly by conditions incident to advancing age,. and partly by frequent or long-continued congestions. Syphi_ litic deposits (gumma) are sometimes found upon the surface of the brain, but they are much more frequently met with at the base, a fact doubtless due to the much greater vascularity of that region. Clinical Experience.—-Kali iod. and Mercurius well sustain their reputation as anti-syphilitic remedies in chronic meningeal affections of the brain. Experience shows, also, that the various remedies used in other forms of meningitis are equally bene- ficial in this whenever the causes can be effectively removed or suspended. Thus all undue mental strain, excessive alcoholic stimulation, veneicy, etc., must be abandoned before the irritation and inflammatory action will yield to any form of medication. Therapeutic Indications.—These are similar to those given under the heads of simple and tubercular meningitis, en- cephalitis and cerebral hyperaemia, which see. The following are special indications in paralysis of the muscles of the eye and face: Causticum.—-Paralysis of the facial and of any or all of the ocular muscles, especially when resulting from cold. CHRONIC HYDROCEPHALUS. 73 Gelsemium.-—-Paralysis of the oculo-motor nerve, or when it gives rise to double vision; also for paralysis of the facial muscles, and of the tongue and organs of speech. Stram0nium.——Paralysis of the ocular muscles when dependent on brain troubles, or when associated with facial paralysis. Kali iod. and Mercurius.——When the paralysis is of syphilitic origin. Nux vom.-—VVhen aggravated by the use of stimulants or tobacco. Spigelia.-—When the paralysis is associated with sharp, stab- bing pains through the head. Opium.-—Paralysis of the ciliary and facial muscles. Auxiliary Treatment,—-The best moral and supporting- measures, in addition to medical treatment, are generally required. CHRONIC HYDROCEPHALUS. Synonyms.—-Dropsy of the Brain, Water on the Brain, Hydrops Capitis; Fr, Hydrocéphale, H ydropsie du Cerveau; Ger, Der Wasserkopf, Hirnwasser-sucht. Definition.—A gradual effusion of serous fluid into the ventricles of the brain, in such quantity as to distend them and enlarge the head. Pathology.—As the ventricles become more and more dis- tended by the gradually accumulating fluid, the hemispheres slowly expand, the convolutions unfold, and the whole cerebral mass becomes thinned and distended, until at last it resembles a mere bag of brain-matter filled by the expanded ventricular membranes and their fluid contents. At the same time both the membranes and the brain substance, instead of becoming softer and less compact, are rendered tougher and denser, the lining membrane of the ventricles thicker and more resisting, the brain-matter harder and tougher. This cannot always, nor even generally, be due to previous inflammatory action; for while there is little, if any, atrophy of the brain substance, there is apparently an overgrowth of the neuroglia, due, probably, to the long-continued mechanical congestion of the tissues. Clinical Experience.—C'alcarea carb., I/Ethusa and Sulphur 6 74 NERVOUS THERAPEUTICS. are said to give the best results in chronic hydrocephalus, al- though Arsenicum is, perhaps, more frequently given than any other remedy. Helleborus, Apis and Digitalis are also frequently prescribed, especially when the urine is scanty and the circu- lation feeble and embarrassed. Arsenicum iod., Kali iod. and Calcarea phos. are given in cases manifesting scrofulous and tubercular cachexiae, tardy dentition, etc. Therapeutic Indications-—Ga1carea carb.—Head greatly enlarged; anterior fontanelle open ,- old, pale, haggard expression of the face, which is thin and wrinkled, or swollen and puffed ; copious sweat on the head, neck and shoulders, especially wheasleeping; scrofulous swelling of the superficial glands. Ethusa cyn.—-Child cannot hold up its head, which is greatly enlarged; lies in a stupor; pulse feeble; pupils dilated and insensible to light; vomits soon after nursing; scrofulous swelling of the cervical and axillary glands. Sulpl1u1'.——Most valuable as an intercurrent remedy; great torpor of the system; dulness of the senses; face pale and ema- ciated; retention of urine; constipation. Helleborus-—Forehead wrinkled and bathed in cold perspira- tion ; urine suppressed or scanty and dark; somnolency, with dulness of the senses; pupils dilated; limbs tremble from weakness; gait tottering ; passive congestion, with serous effusion. Arsenioum.——-The child strikes or clutches at its head, as though for relief; retention or involuntary discharge of urine; breathing anxious and oppressed; special senses dull ; stomach emaciation and muscular weakness ; swelling of the head and face; irritable and weak. Digitalis.—-Head enlarged by copious serous exudation; weak, irregular action of the heart; great prostration ; coldness of the body and limbs; weak feeling at the pit of the stomach -; tendency to faint. Apis mel.——Urine scanty or suppressed; pulse irregular; trem- bling of the limbs, with tottering gait; copious sweat of the head ; stools small; great emaciation and prostration; dry, hot skin, but no thirst; pulse very weak, while the heart beats with great violence. cnnourc HYDROCEPHALUS. 75 Calcarea ph0s.—Child takes no interest in anything; is un- able to hold up its head, which is large and heavy; posterior fontanelle wide open; ears and nose cold; face pale or sallow; great desire for potatoes and other forms of starchy food. Kali iod.——Stupor, with irregular and labored breathing; superficial glands enlarged; urine suppressed; pupils dilated; scrofulous constitution. Apocynum can.—-Forehead projecting, sutures open, head en- larged; stupor, with dulness of the senses, especially that of sight; urine scanty or suppressed; serous exudation. Pl11mbl1m.—Heaviness of the head from dropsical enlarge- ment; pulse small and frequent, or slow and feeble; emaciation, with trembling of the limbs; somnolence, with mental dul- ness; retention or involuntary emission of urine; obstinate consti- pation; constantly growing weaker and more debilitated. Zincun1.-——Small,~ weak pulse; great prostration; coldness of the body; breathing oppressed; limbs tremble and feel heavy; dulness of the special senses; head enlarged, with great out- ward pressure; restlessness, especially at night; vertigo, espe- cially when raised up, with nausea ; constipation. Auxiliary Treatment.—-Hygiene is of great importance in the management of these cases. The head should be sup- ported on pillows, or by some suitable mechanical contrivance, in a comfortable position, and the child exposed daily to fresh air and sunshine. A.liberal supply of good, nutritious, easily digestible food should be given to it with regularity. In short, everything possible should be done to strengthen and build up the system. As for local treatment, it has usually done more harm than good. Tapping appears to have relieved a few cases; but the ordinary result of the measure has been to hasten the fatal termination. Treatment by compression is as cruel as it is senseless, and is now happily abandoned. PART II. DISEASES OF THE SPINAL MARROW AND ITS MEMBRANES. SPINAL HYPEREMIA. Synonyms. Spinal Congestion, Congestion of the Spinal Cord; Fr., Hypéremié de la Moelle Epiniere; Cer., Ritckenmarks- hyperamie; Spinalhypertimie. Definition.——A general or local excess of blood in the spinal cord and its membranes. ' Diagnosis.—Spinal hyperaemia is liable to be mistaken for spinal anmmia, myelitis and spinal meningitis. Hyperaemia of the cord is characterized by more or less anaesthesia or numbness, spinal anaemia by its opposite, hyperaesthesia, which is often excessive. The former is always aggravated by the recumbent position, while the latter is ameliorated by it. Myelitis may be distinguished from spinal hyperaemia by the greater intensity of the symptoms, and spinal meningitis by the severity of the symptoms, by the pains produced by movement of the paralyzed limbs, and by the tonic contrac- tion of the muscles, especially those of the back. Pathology.—-The anmsthesia is supposed to be due to pressure upon the white substance of the cord, which is always greatest when the back is in a dependent position; the same is true of the paralysis; while the hyperaesthesia and mus- cular twitchings are caused, rather, by hyperaemia, and con- sequent overexcitation, of the gray substance. Clinical Experience.—-T he remedies most frequently pre- scribed for this condition of the cord are: Rhus to:v., Lachesis, Silicea, Secale and Lathyrus sat. Next in frequency are: Aconite, Gelsemium, Nux vom., Argentum nit., Oscalic ac., Colchicum, Belladonna, Agaricus and Rhododendron. SPINAL HYPEREMIA. 77 Therapeutic Indications.—Rhus tox.——Ach ing in the spine, with tingling, numbness and paralytic weakness in the lower limbs, especially when caused by exposure to cold, straining, etc ; aggravated by rest or by lying down. Lachesis.—Prickling sensation in the limbs; sinking sensation in the back; stinging pains in the limbs, with numbness and trembling weakness. -Silicea.-——Limbs “ go to sleep” easily, are sore, lame and cold; legs tremble and are very weak; numbness and prick- ling in both upper and lower extremities; pain and laming soreness in the back, increased in the recumbent position. Secale c0r.—Weakness and numbness in the lower extremi- ties; prickling sensations in the legs and feet; paralysis of the bladder and rectum; produces such intense congestion of the cord as to destroy its functions. Colchicum.-—Spinal hyperaemia caused by suppressed per- spiration, or by getting the feet wet; numbness of the limbs, with prickling pains; twitching pains in the limbs and side, with sensation of lameness. , Belladonna.-—Spinal hyperaemia attended by severe pains in the back, which are increased by lying down. Agaricus.-—Laming numbness‘ and formication in the lower limbs; tingling, prickling sensation in all the limbs; violent pains in the back, worse when standing. Ac0nite.—-Paralysis from congestion of the cord; crampy, contractive pain in hand and arm; painful bruised sensation in the spine, attended by stiffness and lameness of the back ; trembling weakness in the lower limbs. Rhododendron.—Paralytic weakness during rest; heavy, weak feeling and formication in back and limbs, worse when at rest, especially when lying down. Argentum nit.—-The pain in theback is relieved by standing; trembling in the lower limbs, as after afatiguing walk; nightly pains in the back. Berberis vulg.—Numb, bruised feeling in the back, worse when lying; paralytic feeling in the limbs, with sensation of tingling and prickling in them. Gelsemium.—Dull, aching pains in the upper part of the 78 NERVOUS THERAPEUTICS. spine, worse after lying down ; pains shooting out from the spine to other parts, and sometimes in the opposite direction, causing the patient to cry out; cerebro-spinal congestions. Arnica.——Spinal congestion caused by overexertion, strain or mechanical injury; also when produced by the cold stage of intermittent fever. Lathyrus sat.-—-Numbness, followed by paralysis, of the lower extremities; band feeling around the body; patient unable to stand or take a step; sometimes unable to distinguish one limb from the other. Auxiliary Treatment.--The hot douche is one of the best local applications in this disease. The water, at a temperature of about 100° F., should be made to fall from a height of two or three feet over the affected part of the cord for a few minutes every day. Very satisfactory results sometimes follow the systematic administration of the constant current of elec- tricity, by passing it through the affected portion of the spine daily for a few minutes at a time, employing as strong a current for the purpose as the patient can conveniently bear. As soon as the numbness and hyperaesthesia disappear, the induced current should be applied to the paralyzed muscles, to excite them to contract. SPINAL ANZEMIA. Syn0nyms.—Anaemia of the Spinal Cord, Anaemia of the Antero-lateral Columns, Spinal Paralysis, Spinal Exhaustion, Myelasthenia, Neurasthenia Spinalis, Reflex Paraplegia, In- hibitory Paralysis, Functional Paralysis of the Cord, Paralysis from Peripheral Irritation; Fr., Paraplégie Refle:ce; Paraplégie Functionelle; Ger., Reflex Paralysis Spinalis. Definition.-—A disease characterized by such a general or local deficiency of blood in the vessels of the spinal cord as to impair its functions. Diag‘n0SiS.—Spinal anaemia may be distinguished from spinal hyperaemia, first, by the fact that the symptoms, instead of being aggravated by the recumbent position, are always ameliorated by it; secondly, by the fact that it is not pro- SPINAL ANEMIA. 79 i gressive; thirdly, when the bladder is involved it usually pre- cedes the paralysis. Anaemia of the antero-lateral columns is distinguished from that of the posterior columns by the absence of any considerable disturbances of sensibility, and by the presence of well-marked, though incomplete, paraplegia. Pathology:-Reflex paraplegia and spinal neurasthenia are believed to be due to spinal anaemia because, there being no visible alterations of structure in these cases, the symptoms admit of no other rational explanation. The irritation is sup- posed to operate (1) upon certain sensory nerves which trans- mit the impression to the gray matter of the spinal cord, from which it is reflected (2) either along vaso-motor nerves regu- lating the caliber of the bloodvessels which supply either (a) the portion of the spinal cord in relation with the paralyzed parts, or else (b) the nerves of the paralyzed muscles them- selves. In either case the irritation is supposed to lead to a persistent spasm of certain vaso-motor vessels, so as to cause an anaemic condition of certain vascular territories in the spinal cord, or else of the related nerve-trunks and muscles, and thus, by interfering with the nutrition of the parts, de- prive them to a greater or less extent of their functions. Clinical Experience:-Nux vom., Phosphorus and Strychnia appear to be the remedies most frequently employed in this disease. Rhus ton, though it sometimes appears to help the paralytic condition, seldom does any permanent good in spinal anaemia. Arsenicum, China and Calcarea phos. are ex- cellent remedies, especially when the disease is associated with general anaemia, or with an impoverished condition of the blood. Therapeutic Indications:-Nux vom.—Gre-at debility of the nervous system, with partial paralysis; reflex paralysis; paralysis from nervous exhaustion; pain as from a bruise in the small of the back; heaviness and weariness in the lower ex- tremities; torpor of the liver, stomach and bowels; paralysis of the bladder. Pl1osphorus.—Bruised feeling in the back and limbs; great heaviness and weariness from the least exertion; spinal neu- rasthenia ; extreme mental and physical prostration. 80 NERvoUs THERAPEUTICS. Strychnia phos.-——One of the best remedies we have for anaemia of the cord; paralysis from exhaustion of the reflex motor power of the spinal nerve-cells. Erythroxylon coca.—Sleeplessness and disinclination to work or move; mental depression, with anxiety and palpitation of the heart; loss of appetite; constipation, with abdominal dis- tension ; oppression of breathing, arising from debility; faint- ing fits from nervous weakness; coldness of the extremities; . general debility, the least exertion being attended by fatigue. China.—-Paralysis due to general anaemia or loss of vital fluids ,- spinal anaemia following severe and exhausting illness; neu- rastlienia spinalis induced by overexertion, either bodily or mental; nervous trembling of the lower limbs. Arsenicum.—-Paretic condition of the lower limbs, especially when associated with general anamia ; constant disposition to lie down; sensation of weakness in the small of the back; para- lytic weakness preceded or accompanied by excessive or watery alvine discharges; trembling of the limbs from debility; rest- lessness, especially at night; thirst for small quantities of water. Calcarea phos.—-Coldness and weakness of the lower extrem- ities from defective circulation of blood in them ; nervous pros- tration, with great depression of spirits; face pale and wan ; sore, bruised feeling in the back, with desire to lie down upon it. Kali ph0s.—Spinal anaemia from exhausting diseases; reflex paraplegia, with burning pains, aggravated by rest, but worst on first moving about. Alumina.-—Paralytic symptoms induced by cold, or when as- sociated with pain in the back; coldness of the surface; weak- ness and heaviness in the lower extremities; great exhaustion after slight exertions ; unrefreshing sleep; weakness of the genito-urinary organs. Lycopodium.—Great nervous prostration; neurasthenia from Spinal anaemia; flatulency; constipation. Auxiliary Treatment.—Good, nutritious food, such as milk, eggs, beef, etc., and an abundance of fresh air and _sun- shine, should always be provided. Change of climate and scenery, an ocean voyage, pleasant company, agreeable occupa- tion, etc., are often highly beneficial in these cases. Every SPINAL IRRITATICN. 81 source of peripheral irritation to which the patient is exposed should be removed or guarded against. Whatever benefits the general health will benefit the spine in these cases, and vice versa. See Cerebro-spinal anxmia. SPINAL IRRITATION. Syncnyms.—-Anaemia of the Posterior Columns of the Spinal Cord, Posterior Spinal Anaemia, Neuralgia of the Spine, Spinal Neuralgia, Rachialgia; Fr., Rachialgie; Ger., Ritch- gratschmerz. ' Definition.—A condition characterized by a greater or less degree of spinal tenderness, and by a morbid excitability of the nerves proceeding from the affected portion of the cord. Diagnosis.——-Spinal irritation is liable to be mistaken for spinal hyperaemia, hysteria, chronic myelitis and spinal men- ingitis. In spinal congestion there is, instead of hyperaesthesia, more or less anaesthesia, numbness and formication ; and when a sponge, dipped in hot water, is applied to the spine an intense aching is produced, which is not the case in spinal irritation. Chronic myelitis is characterized by anaesthesia, painful muscular contractions and paralysis——symptoms that do not belong to this disease. Spinal meningitis is a far more acute disease than spinal irritation, the hyperaesthesia and pains on motion being very much more severe. Hysteria often resembles spinal irritation so closely as to be mistaken for it; and, indeed, it frequently coexists with it in the same patient. It may be best distinguished by the history of the case. Path0l0gy.—Hammond and others regard spinal irritation as being essentially an anaemia of the posterior columns of the cord, basing their opinion on the following grounds: 1st, the general condition of the patient is one of debility, a condition which the exciting causes of the disease tend to produce; 2d, the symptoms indicate that the disease is seated in the posterior columns of the cord; 3d, whatever improves the quality of the blood, or increases the amount of it in the spinal vessels, always benefits the patient, and vice versa. Of course, it will only apply to those cases in which the nerves of sensibility are 82 NERVOUS THERAPEUTICS. alone affected; when those of the motor sphere are implicated, the antero-lateral columns must be involved. But this view » appears to be too exclusive. Some cases are best explained by supposing that the two opposite conditions of hyperaemia and anaemia coexist in different portions of the cord, while in others the symptoms appear to be due to hyperaemia alone. It is generally conceded, however, that in the majority of cases the essential pathological condition is one of anaemia, involving the posterior columns of the cord. Clinical Experience.—The remedies which have proved curative in this disease are: Cocculus, Gelsemium, Cimicij"uga, Strychnia phos., Hypericum, Belladonna, Tarantula, Secale cor., Natrum mur., Tellurium, Rhus toa:., Ignatia and Scutellaria. In addition to these, the following remedies have benefited particular cases: Santonine, Silicea, China, Phosphorus, Sulphur, Zincum met., Calcis hypophos., Piper menth., Naja, Veratrum oz'r., Calcarea carb. and iod., Nucc oom., Colocynth., Kali hypophos., Agaricus and Aconite. Therapeutic Indications.--Cocculus.—-Great hyperaesthesia of all the senses, and an exalted susceptibility to impressions; dreadful headaches and sleeplessness; her sufferings are for- gotten when her mind is turned away from herself; pain in the lower portion of the spine; stiffness of the neck; palpitation of the heart and oppression of the chest; trembling of the limbs; numbness of the right upper and lower limbs. Gelsemium.—-Stiffness and pain in the back of the head and neck; sleeplessness from soreness and pain in the back; great depression of spirits; extreme weakness and prostration. Cimicifuga.—-Severe aching pain in the lower part of the back and in the occiput, with occasional shooting pains in the chest, and great weakness, amounting almost to paralysis, of the lower extremities; constant nausea and retching on press- ure upon the spine, between the fourth and fifth vertebrae; fre- quent fainting; palpitation 011 least movement; amenorrhoea; aggravated by cold, movement, and at the menstrual period. Strychnia phoS.—Tenderness on pressure over the dorsal vertebrae; pain, sometimes burning, but chiefly aching, ex- tending frequently to the front of the chest, causing a feeling SPINAL IRRITATION. - 83 of uneasiness and nausea; cold feet, covered with clammy perspiration; insomnia. Hyperioum.-—-Tenderness of the whole spine; pain in the joints, accompanied by mania; laming-aching in the dorsal region; frightful illusions, screaming if approached; no recol- lection of the attack ; stiches and paroxysms of pain in different parts of the body. ' Belladonna.-——Pressure over the dorsal vertebrae causes her to cry out and turn pale and nauseated; continual burning pain in the spine; tenderness of the stomach, with nausea and vomiting on eating; pressure on the fourth dorsal vertebra produces a shriek, followed by a dry, violent cough, red face, headache in forehead, photophobia and perspiration. Tarantula.—A slight touch along the spine causes spasmodic pains in the chest and great distress in the cardiac region; also cardiac disturbances, intense headache and sensation of burning all over the body; muscular contractions; convulsive movements, tremblings and general chilliness. Secale cor.- Tenderness over the superior spinous processes, with stiffness of the neck; pains radiate from the affected portion of the spine to the chest, producing anxious, oppressed breathing, with palpitations, and tendency to convulsive movements and cough. Natrum mur.—Sensitiveness of the spine, with pain in the back; eyes sore on pressure; supraorbital neuralgia, with nausea and sensitiveness to bright lights; vision clouded with black spots; hemiopia; sleeplessness; morning headache; anorexia; constipation; restlessness and debility. Tellurium.—Tenderness of the spine, with extreme sensitive- ness to pressure; patient so sensitive and irritable as even to dread the approach of any one. Rhus t0x.—Violent pain in the head and down the back, with extreme sensitiveness of the spine to pressure; lies on her back with the head and spine drawn backward; the slightest touch or movement causes extreme pain; anxious, oppressed breathing, with violent palpitations, occurring i11 paroxysms; complete sleeplessness. Ignatia.-—Aching pain as if bruised in the cervical and 84 ' NERvoUs THERAPEUTICS. dorsal portions of the spine; lancinating pain in the nape of the neck, also in the small of the back, extending through the loins; pains increase by pressure over the spine; cases com- plicated with hysteria. Auxiliary Treatment.—The \Veir Mitchell treatment of absolute rest, combined with gentle galvanization of the spine by the constant current, positive pole below,negative above, is perhaps the best local treatment, in most cases, when it can be rigidly carried out; but where reflex excitations to distant parts, causing palpitations, neuralgia, congestion and engorge- ment of pelvic and abdominal organs, etc., are due to engorge- ment of the cord, rather than to anaemia, cold to the spine is found to be eminently remedial. Other cases, on the contrary, are benefited by hot water to the spine. The diet should in all cases be generous. SPINAL HZEMORRHAGE. Syn0nymS.——Haemorrhage into the Spinal Cord or its Membranes, Spinal Apoplexy, Haemorrhagia Medulla Spi- nalis, Haematomyelia ; Fr., Hémorrhagie Intrarachidienne, Him- atomyéle, Apoplerrie de la Moelle Fgoiniere; Ger., Rilckenmarks- apoplevie. Definiti0n.—Haemorrhage into either the substance of the cord or into its membranes, to which latter variety most cases of spinal haemorrhage belong. Diagn0siS.—Usually, the chief reliance must be upon the history of the case, the existing symptoms affording but few diagnostic marks. When, however, paraplegia occurs sud- denly, and is the result of an accident, we shall generally be warranted in attributing the paralysis to spinal haemorrhage. Path0l0g'y.—When effused into the substance of the cord, the clot, which is almost invariably seated in the gray matter, shows a greater tendency to extend in the course of the long axis of the cord than laterally, and varies in length from half an inch or less to several inches, sometimes involv- ing the entire central portion of the cord. In the meningeal variety the blood is generally extravasated between the bones SPINAL MENINGITIS. 85 and the dura mater, but very rarely it is etfused into the pia mater, where it more or less compresses the cord and produces the anaesthesia and motor paralyses observed in such cases. When the extent and situation of the haemorrhage are such as to cause irritation instead of compression, the effect is to pro- duce hyperaesthesia and spasm. Clinical Experience—-—Hypericum, Arnica and Calendula are given after severe injury to the spine followed by numbness and paralysis, with a view to promote the absorption of any clot which may have formed and is causing compression. Secale cor. is given to prevent further effusion by contracting the spinal bloodvessels. Therapeutic Indications.—These are given under the heads of cerebral haemorrhage, spinal paralysis and anmsthesia, which see. Auxiliary Treatment.—Whenever there is reason to appre- hend the existence of spinal haemorrhage, ice should be applied to the spine and the patient made as quiet and comfortable as possible. Absolute rest is essential, not only to prevent fur- ther effusion of blood, but to render the consequences of the haemorrhage as light as possible. SPINAL MENINGITIS. Synonyms:-Inflammation of the Spinal Meninges, Menin- gitis Spinalis; Fr., Méningite Spinale. DURA MATER: Spinal Pachymeningitis; Fr., Pachyméningite Spinale; ARACHNCID: Spinal Arachnitis; Fr., Arachnite Spinale; PIA MATER: Spinal Leptomeningitis; Fr., Leptoméningite Spi- nale ; Ger., Rilckenmarkshautentzilndung. Definition:-Inflammation involving one or more of the membranes of the cord. As it is usually limited to the soft membranes, it is immaterial whether we call the disease spinal meningitis or spinal leptomeningitis. Diagn0sis.—The diagnosis of spinal meningitis, either acute or chronic, depends upon the presence of the following symptoms: (1) pains in the back and limbs, greatly aggra- vated by every movement of the spine; (2) muscular rigidity 86 NERVOUS THERAPEUTICS. similar to, but less severe and general than, that of tetanus; (3) hyperaesthesia and increased reflex excitability; and (4) reten- tion of urine and faeces, followed by more or less paralysis, anaesthesia and incontinence of urine and faeces. The absence of cerebral symptoms is sufficient evidence that the disease is not tubercular. Clinical Experience.—The remedies which appear to stand the highest in the treatment of this disease are: Aconite, Bella- donna, Bryonia and Nux uom. Others which have received clinical indorsement are: Rhus to:c., Causticum, Plumbum, Hy- pericum, Cuprum, Veratrum oir., Mercurius, Secale cor. and Oxalic ac. Therapeutic Indications.-—-Aconite.—-High fever, with bor- ing pain in the spine, increased on motion; painful stiffness in the dorsal region, extending to the neck; numbness extend- ing from the small of the back into the lower limbs; formica- tion in the arms; spasms caused by spinal inflammation; insensibility and coldness of the hands and feet; the arms hang powerless, as if paralyzed. Belladonna-,-Lancinating pains in the vertebrae, resembling stabs with a knife; tonic muscular contractions; cramplike pain in the middle of the spinal column; painful stiffness in the back of the neck;. intense dyspnoea, as if the chest were violently compressed; complete or incomplete paralysis, with or without incontinence of urine. Bry0nia.—Sticking pains in the back on the slightest move- ment of the spine; promotes absorption of serous eflusion, and thus relieves paralysis from compression; sticking pains in the chest, with fever. Nux v0m.—Violent pains in the back, especially in the dorsal and lumbar regions; pains extending from the back to the sternum, producing shortness of breath; pains aggravated by movement; hypochondriac and epigastric regions sensitive to pressure ; numbness and weakness of the arms and legs; reten- tion of urine; constipation. Hypericum-—Fever, with wild, staring looks, hot, bloated face, thirst and white-coated tongue; painfulness of the back from injury to the spine, greatly increased by any movement SPINAL MENINGITIS. 87 of the body; the slightest movement of the spine extorts cries ; the cervical vertebrae sensitive to the touch; spells of short, hack- ing cough and difficult breathing; desire for warm drinks. Plumb\1m.—Chronic cases, attended with frequent attacks of violent colic, with retraction of the abdominal walls; paralyzed parts greatly emaciated; limbs become painfully contracted; coldness and paralysis of all the limbs, especially of the lower; extreme constipation. Cuprum.—Suffocative breathing from spasm of the respiratory muscles; rigidity, with painful contractions of the limbs, toes and fingers; excessive weakness, especially in the lower ex- tremities; painful jerkings in various parts of the body and limbs; paralysis, with incontinence of urine. Rhus tox.——High fever from getting wet, or from repercussion of an exanthem; numbness, and loss of sensibility and power of motion in the limbs; formication; dyspnoea; inflammation following concussion of the spine. Secale cor.—-Spinal meningitis, attended with suppression of urine; spasms, followed by paralysis, numbness and insensi- bility. Mercurius.——-Violent pain in the spine, aggravated by motion; great restlessness and sleeplessness at night, or when warm in bed; paralysis of the lower limbs, bladder and rectum ; anaes- thesia of the skin; occasional jerks in the paralyzed parts. Physostigma.—-Spinal meningitis, with tetanic spasms; back very weak; stiffness and pain all along the spine, with incli- nation to bend forward; stiffness of the neck, with feeling of drawing and tension. StraIn0nium.——Constant pain in cervical and upper dorsal re- gions of the spine, which is sensitive to the touch; sudden jerks through the body; tonic spasms, with consciousness un- aflected ; muscles will not obey the will; trembling contractions Cicuta.——Violent spasmodic pains in the paralyzed lower limbs; trembling of the limbs during remission; painful stiff- ness in the muscles; frequent involuntary jerking and twitch- ing in the limbs, followed by paralysis; feeling of soreness in many parts of the body. Kali iod.—Constant violent pain in the small of the back; 88 NERvoUs THERAPEUTICS. spasmodic contraction of the muscles; fever, with excessive thirst; burning sensation at the pit of the stomach; great desire to go into the open air; paralysis of the lower extremities. Auxiliary Treatment:-Ice to the spine usually gives most relief in acute cases, especially to the pains. Chronic cases are benefited by the primary galvanic current and by the electro- cautery. The patient should lie on his side or face, on a com- fortable spring mattress, in a large, quiet, airy roo1n. Animal broths, soups, milk, eggs and other nutritious articles of food should constitute the diet, strengthened, when required, by a moderate allowance of stimulants. Bed-sores should be pre- vented as long as possible, and after they have formed they should receive careful attention. A mild current of electricity passed daily through the affected parts will often cause them to heal. Great care should also be taken to relieve the blad- der and rectum, especially after paralysis has occurred. MYELITIS. Syn0nyms.——Inflammation of the Spinal Cord, Inflamma- tory Softening of the Cord, Myelitis Acuta; Fr., Myélite, Inflam. de la Molélle Epiniere, Ramollissement de la Molélle 1l'piniere,' G'er., Rilckenmarksentzilndung, Erweichun g des Rttckenmarks. Definiti0n.—An acute inflammation of the whole, or of any part, of the substance of the spinal cord. Diagnosis.—The history of the case, especially in traumatic injuries, is often sufficient of itself to determine the diagnosis. The disease may also be distinguished from other affections of the spine by the characteristic symptoms of the disease, such as the “ band feeling” about the body and the rapid develop- ment of paraplegia, together with the reflex phenomena of pain and convulsive movements. Pathology.-The essential pathological feature of acute myelitis consists in hypertrophy of the neuroglia, and conse- quent atrophy or degeneration of the nervous elements of the cord, resulting finally in inflammatory softening, or else in sclerosis. Clinical Experience.——The remedies most frequently em- MYELITIS. 89 ployed in myelitis are: Aconite, Gelsemium, Belladonna and Mercurius in recent cases; and Arsenicum, Plumbum, Oxalic ac. and Strychnia in chronic cases. Arnica, Hypericum, Rhus tow. and Sulphur are most frequently given in traumatic cases. Therapeutic Indications.—Aconite.-Acute cases, attended with high fever, spasms, numbness, formication, icy coldness of hands and feet. Push the remedy to the extent of produc- ing a profuse perspiration. Gelsemium.-—Cerebro-spinal symptoms, such as confusion of the head, extending from the occiput to the forehead; paresis of tongue and glottis ; pains in the back of the head and spine, with pains darting laterally from the latter to other parts; spinal exhaustion; loss of voluntary motion; incontinence of urine; myelitis involving the anterior horns of gray matter. Belladonna.—Both acute and chronic cases, where there are pains in the back, with weakness and weariness; paralysis of the ocular muscles and iris; partial or general paralysis; dysp- noea; tonic and clonic spasms; chronic cases caused by retro- cession of eruptions. Mercurius.—Great restlessness and sleeplessness, especially at night; pains in the spine, violent, and worse from motion; , paralysis and anaesthesia of the lower limbs; occasional jerking in the paralyzed muscles. Plumbum.—-Chronic cases, especially when attended by colicky pains; painful tonic contractions; paralyzed parts become greatly emaciated; dyspnoea from hyperaesthesia of the inter- costals; atrophy of the muscular tissues; extreme constipation. Arsenicum.-—Chronic cases attended by great dyspnoea and anxiety; twitching, trembling, violent starting and weariness in the limbs; tetanic spasms; great restlessness, especially at night, with sleeplessness. Angustura.—Twitching and jerking along the back like elec- tric shocks; tonic contraction of the muscles of the jaw; bruised pain in the dorsal region, or in the muscles of the neck; tension of the facial muscles; tremulous stitches in the thighs. Secale cor.-——Violent pains in the back, especially in the sacral region ; muscular twitching and jerking in the limbs; tingling 90 NERvoUs THERAPEUTICS. in the back, extending to the fingers and toes; painful contrac- tion of the flexor muscles; paralysis and anaesthesia of the limbs; especially indicated in cases complicated with spinal meningitis. Gausticum.—Lancinating pains iin the back, arresting the breathing; numbness and insensibility of the fingers and toes, with ice-cold sensation and tendency to cramp. Veratrum alb.——Aching and sticking pains in the back; . tingling in the hands; painful jerking in the limbs; cramps in the legs ; paresis. ArI1ica.—Subacute and chronic cases of traumatic origin; should be given previous to the setting in of the degenerative process. Phosphorus.—Chronic cases resulting from sexual excesses, or where there is a tubercular condition of the system; paroxysmal pains in the back, with paralytic weakness; dyspnoea, with sensation as if the chest was oppressed by a load resting upon it. " Picric ac.—Tonic and clonic spasms; extreme weariness and exhaustion; tendency to softening of the cord; great chilliness, can’t get warm; sensation of worms crawling over the ears ; paralysis. Oxalic ac.—Limbs stiff, numb, weak, heavy, powerless; muscular twitchings ; acute pain in the back, with numbness and weakness, extending to the limbs; pains excited and aggravated by movement; they are usually like short stitches, confined to a small spot, and lasting only a -few seconds. Auxiliary Treatment.——This is similar to that recom- mended under the head of spinal meningitis, which see. Kafka also advises the spray douche, frequently repeated, to the spinal column. MYELOMALACIA. Syn0nyms.—Softening of the Spinal Cord, Simple, White, Non-inflanimatory Softening, Mollities Medullae Spinalis; Fr., Ramollissement de la Moélle Epiniere ; G'er., Erweichung des Rilckenmarks. MYELOMALACIA. 91 Definition.—A primary, non-inflammatory, and apparently idiopathic, softening of the spinal cord. Diagn0sis.—The condition, in striking contrast with every other affectiori of the cord, is best known by its negative symp- toms, there being no pains or exalted sensibility, nor any muscular twitchings, spasms or contractions, even when the whole structure of the cord is involved in the process. Path0l0g‘y.——Some writers still adhere to the old notions concerning softening of the cord, regarding as inflammatory not only the forms resulting from the so-called acute central myelitis and myelitis diffusa, but also the large class of primary softenings, due chiefly to vascular disturbances, and which belong to the degenerative type of diseases. Even secondary degenerations of the cord are sometimes classed as inflammatory, notwithstanding the fact that hyperplasia of the neuroglia subsequently sets in, giving rise to sclerosis. There is, however, but one true form of inflammatory softening, namely, that resulting from acute myelitis. All others belong to the category of non-inflammatory softenings, and constitute the simple white softening known as myelomalacia, in which the tissues of the cord are found to have undergone fatty and granular degeneration, the constituents consisting chiefly of oil-globules, debris of nervous matter, and broken-down con- nective tissue. (Further information on this subject may be obtained by consulting the author’s article on “ Diseases of the Nervous System” in Arndt’s System of Medicine, Vol. II, pp. 610,614) Clinical Experience.—All the clinical experience we have on this subject is given under the head of myelitis, which see. Picric ac. will produce softening of the cord, but whether it is capable of restoring the degenerated cord to a state of integrity is another question, and remains to be proved. Therapeutic Indicati0ns.——These are given under the heads of spinal hyperaemia, myelitis and spinal paralysis, which see. Auxiliary Treatment.—Hopeless as may be the case, so far as a cure is concerned, much may be done toward render- ing the patient more comfortable and prolonging his life. 92 NERvoUs THERAPEUTICS. Thus, the weakened cord should be guarded against any further injury by carefully avoiding any sudden jar or fall; bed-sores should be prevented or promptly and methodically treated; and the bladder should be emptied with regularity, either spontaneously or, as will generally be required, by means of the catheter. Passive exercise in the open air should be taken as long as practicable; and in no case should the patient be unnecessarily deprived of fresh air and sunshine, which are no less essential to his support than good and wholesome food. SPINAL PARALYSIS. Syn0nyms.——Paralysis of the Spine, Spinal Palsy, Para- plegia, Paraplexia; Fr., Paraplégie, Paralysie Spinale; Ger., Paralysis Spinalis, Spinalparalysie, Spinalliihmung. Definition.-—Paralysis of the lower extremities, with or without paralysis of the lower part of the trunk, bladder and rectum. Diag‘n0siS.——There are three distinct forms of organic paralysis depending on the seat of the disease, namely, the hemiplegia or cerebral, the paraplegic or spinal, and the general or cerebro-spinal. To these may be added the reflex or peri- pheral, which usually assumes the paraplegic form, and may be known partly by the absence of the distinctive symptoms of organic paralysis, and partly by the rapid improvement which usually attends the removal of the irritation which causes it. Pathology.—-The pathological changes which characterize the various forms of organic paraplegia will be given in the succeeding articles treating of the different varieties of spinal paralysis, which see. Toxic and reflex paraplegias exhibit no pathological alterations, being simply due to vaso-motor spasm caused by disease or injury of remote organs, without any appreciable evidences of organic disease in the cord or its membranes. Clinical Experience.e—Reserving for special mention under their appropriate heads the clinical experience pertaining to the several forms of organic paraplegia, we shall here give only what relates to the toxic and reflex varieties, viz.: SPINAL PARALYSIS. 93 (a) Toxrc PARALYSIS. When caused by lead poisoning: Kali iod., Opium, Cupr., Plat. When caused by mercury: Nitric ac., Sulph., Hepar Sulph., Stram., Staph. When due to arsenical poisoning: Ferr., Chin., Hepar sulph., Nux vom., Graph. (b) REFLEX PARALYSIS. When caused by worms : Cina, Santonine, Tereb., China, Ign., Cicuta. When due to dental irritation: Cham., Bell., Gels., Acon., Hyos., Stram., Cupr., Ign., Cicuta. When produced by intestinal irritation: Merc., Arsen., China, Phos. ac., Baptis., Ipec., Verat., Calc. When due to genito-urinary irritation: Bell., Apis, Canth., Dulc., Equise., Hyos., Gels., Lycop., Cactus. When caused by diphtheria: Gels., Arsen., Natr. mur., Rhus tox., Lach., China, Phos., Kali phos., Nux vom., Ferr. When caused by cold or dampness: Dulc., Gels, Rhus tox., Apis, Verat., Bell. When due to external injury: Arnica, Hyper., Cicuta, Rhus tox., Sulph. When caused by pleurisy or pneumonia: Bry., Phos., Tartar emet., Sang., Sulph. When due to sexual excesses: Helonias, Agnus cast., Phos., Nux vom., China, Pic. ac., Nit. ac., Dios., Sarsap., Aurum, Sepia. ' When due to exhausting diseases: China, Phos., Arsen., Zinc. phos., Pic. ac., Calc., Carbo veg., Phos. ac., Nux vom., Calc. hypophos. Therapeutic Indications.——These will be found under the various forms of paralysis hereafter to be described. See, also, spinal meningitis, myelitis, locomotor ataxia and spinal concussion. 94: NERVOUS THEBAPEUTICS. ACUTE ASCENDING PARALYSIS. Synonyms.—Acute Progressive Paralysis, Landry’s Paraly- sis, Paralysis Ascen dens Acuta; Fr., Paralysie Ascendante Aigulé ; Ger, Paralysis Ascendens Acuta. Definition.—An acute disease of the spinal cord, character- ized by a rapidly progressive paralysis, and unattended by any appreciable lesion. Diagnosis.—This disease may be distinguished from the “ acute spinal paralysis of adults,” and also from subacute forms of spinal paralysis, (1) by the absence of rapid muscular atrophy, and (2) by the fact that the electrical excitability of the muscles is unimpaired. Moreover, the disease is regularly progressive in its character, in which respect it differs from acute spinal paralysis, where the impairment of muscular power occurs simultaneously in every part affected. Patho1ogy.——No pathological changes, not even hyperaemia, have yet been discovered after death by this disease, either in the cord or in its membranes. The disease is supposed to be due to some peculiar disturbance of nutrition. Clinical Experience:-Aluminum met., Ledum, Cocculus and Gelsemium occupy the first rank in this disease, and Phosphorus, Rhus tox., Nux com. and Secale cor. the second. Therapeutic Indications.——A1uminum met.— Wl1ile the paralysis is confined to the lower limbs, or when there is so much heaviness of the legs that the patient is scarcely able to lift them, or when they are so weak that he is obliged to sit down, and experiences great weariness even when sitting; staggers in walking; numbness of heel and pain in the sole of the foot when stepping ; constant inclination to lie down. Ledum.—Paralysis ascending from the feet upward; pains in the soles of the feet when walking; sensation as if the posterior muscles of the thighs were paralyzed. (l0cculus.—-Paraplegia occurring in debilitated nervous per- sons, and where the circulation is impeded or sluggish; gen- eral sense of prostration from paralysis of organic life ; sense of constriction through the whole spine. Gelsemium.-—General sense of helplessness, arising from the SPINAL PARALYSIS or ADULTS. 95 muscles not obeying the will-power of the patient; complete re- laxation of the whole muscular system ; pain in the back of the head and neck; dimness of vision; great drowsiness. Picric ac.—I believe this to be the nearest similium we have; the great sense of prostration and the acuteness of the symp- toms appear to call for it, but it should be used comparatively high; it ought to cure in the 30th potency. Nux V0m.—-Paretic condition, in which the power of voluntary motion is not wholly lost ; feeling of great weakness, especially in the back; staggers in walking, and sometimes falls; paral- yzed parts numb and cold; paralysis from exhaustion of the spinal cord; drags his feet in walking. Rhus tox.-—Paraplegia attended with painful stiffness, ting- ling and numbness in the paralyzed limbs; pain in the back ameliorated by lying on something hard; paralysis of the rec- tum and bladder, as well as of the lower extremities. Phosphorus.—Where the paralysis seems to depend on per- verted nutrition ; pains in the soles of the feet, with sensation as if they were asleep; insupportable pains in the spine, pre- venting walking; partial contraction of the affected muscles, with formication and tearing pains. Secale cor.—Severe spinal pains, especially in the sacral re- gion; paralysis of the lower sphincters; destroys the activity of the cord. Auxiliary Treatment.—The majority of cases are so acute that but little good can be expected of accessory treatment. The constant galvanic current to the spine may, however, prove to be of some benefit, if methodically applied. SPINAL PARALYSIS OF ADULTS. Synonyms.-—Atrophic Spinal Paralysis, Inflammation of the Anterior Horns, Poliomyelitis Anterior; Fr., Paralysie Spinale Atrophigue, Paralysie Spinale de l’Adulte; Ger., Spinallc'th- mung bei Erwachsenen, Poliomyelitis Anterior. Definition.-—A peculiar form of paralysis in the adult, acute, subacute or chronic, resulting from inflammation and degeneration of the gray matter of the anterior horns of the 96 NERVOUS THERAPEUTICS. spinal cord, and followed by more or less atrophy of the paralyzed muscles. Diagnosis.——The regressive character of the muscular weakness and paralysis, almost, if not wholly unattended by febrile symptoms, but accompanied by wasting of the limbs, by abolition of the patellar tendon reflex, and by sensations of numbness, yet without loss of tactile sensation, and without paralysis of the bladder or rectum, will render the diagnosis clear and indisputable. It may be distinguished from that form of peripheral neuritis which is attended by paralysis and muscular atrophy, by means of the following table: Poliomyelitis. Peripheral N euritis. Disease usually begins suddenly. Paralysis regressive. Involves at the start all the members affected, some parts quickly recovering. Usually no pain. May be general hyperaesthesia at the beginning. Muscles not sensitive to pressure. N 0 recovery after the disease has lasted some time. Sets in gradually. . Paralysis progressive. Involves differ- ent members, generally in the na- ture of an ascending palsy. Pain is usually continuous; especially marked upon handling, and in- volves certain nerves. Muscles sensitive to pressure. Perfect recovery may take place after the paralysis and atrophy have lasted a long time. Patho1ogy.—The pathological changes in the cord are chiefly confined to the anterior horns of gray matter, and consist in atrophy and yellow pigmentation of the motor nerve-cells, and in centres of softening, showing that the disease is essentially a myelitis. Whether, as Hammond supposes, the muscular atrophy is due to the destruction of trophic cells in the cord, of the existence of which we have no other evidence, or whether, with Charcot, we refer it to atrophy of the motor cells alone, there can be no doubt of its dependence on the spinal affection, which is always associated with it. Clinical Experience.——The remedies which seem to have done the most good in this disease are: Gelsemium, Belladonna, Acomlte, Phosphorus, Strychmla, Rhus tom. and Argentwm nit. INFANTILE SPINAL PARALYSIS. 97 Therapeutic Indicati0ns.——These have already been given under the head of myelitis, which see. Consult, also, spinal hyperamia, spinal meningitis and progressive muscular atrophy. Auxiliary Treatment.——After the inflammatory process has been arrested, the paralyzed and atrophied muscles should be stimulated to contract by the methodical application of electricity. Massage is also useful in these cases, especially the electro-massage of Dr. Butler. IN FANTILE SPINAL PARALYSIS. Syn0nyms.——Essential Paralysis of Childhood, Antero- spinal Paralysis of Infancy; Fr., Paralymle Essentielle de l’En- fance, Paralysie Atrophtque Gravlsseuse de l’Enfanee; Gen, Spvlnale Kinderléihmnng. Definition.-—An acute disease of the spinal cord in chil- dren, characterized by the three successive stages of fever, mus- cular paralysis and atrophy. Diagnosis.—The fact that progressive muscular atrophy sometimes attacks children has led occasionally to the mistake of confounding it with this disease, from which it may be differentiated as follows: Infantile Spinal Paralysis. Progressive Muscular Atrophy. Causes unknown. Heredity in some cases; in others, ex- posure to wet and cold and exces- sive muscular exertion. Patients, infants and children. Mostly adults. Always acute. Always chronic. The paralysis appears first, and is fol- The atrophy appears first, and the mus- lowed later by muscular atrophy. cular weakness and paralysis de- pend upon its extent. Course of the atrophy stationary or re- Always progressive. gressive. Electrical reaction corresponds to the Electrical irritability altered according degeneration of the cord. to the extent of the muscular atrophy. Pathology.—-As in spinal paralysis of adults, the essential lesion in this disease is found to be situate in the anterior 98 NERVOUS THERAPEUTICS. horns of gray matter, and to consist of a myelitis, which results in an atrophy of the part affected, a degeneration of its structure and a disappearance of its cell-elements. Clinical Experience.—-Gelsem/tum, Rhus tox., Belladonna, Atropine, Nux vom., Strychnia and Cocculus are preferred in the more acute, and Phosphorus, Secale cor. and Plumbum in the less acute cases. Therapeutic Indications.—-These have already been given under the head of myelitis, which see. Consult, also, spinal hyperwmia, spinal meningitis and progressive muscular atrophy. Auxiliary Treatment.—Dr. Mossdorf claims to have treated a large number of cases successfully with the descending cur- rent of central galvanization of the spinal cord. In some cases over one hundred applications were made before motility was restored. So long as the paralyzed muscles retain their electro- contractility the treatment by electricity may .be made effec— tive. The number of cells to be used is best determined by trial. The positive electrode should be placed over the nerve- trunks supplying the atrophied muscles, and the negative upon the affected muscles themselves, interrupting the current from time to time by slowly lifting and replacing the negative sponge. Should the physician be called during the acute or inflam- matory stage, the cold douche, frequently applied to the spine, will be of benefit. PSEUDO-HYPERTROPHIG SPINAL PARALYSIS. Synonyms. —— Pseudo-Hypertrophic Muscular Paralysis; Lipomatosis Musculorum Luxurians, Atrophia Musculorum Lipomatosa; Fr., Paralysie Pseudo-Hypertrophigue, Paralysie Myosclérosique, Paraplégie Hypertrophique de l’Enfance; Ger., Jlluskel-atrophie mit Interstitieller I/ipomatose. Definition.——A progressive paralysis, belonging almost ex- clusively to infancy and childhood, caused by inflammation of the anterior tract of gray matter of the spinal cord, in which certain muscles appear to be hypertrophied, although the ultimate fibres of the affected muscles atrophy. GLOSSO-LABIO-LARYNGEAL PARA 1.YsIs. 99 Diagnosis.—The gradually advancing paralysis of the lower extremities, accompanied by an enlargement of the gastroe- nemii muscles, and afterward of those of the thigh and gluteal region, will serve to distinguish it from every other affection. Pathology.-—The pathological changes in the cord consist in atrophy and disintegration of the nerve-cells of the anterior horns, and sclerosis of the lateral columns. The muscular hypertrophy appears to be due to proliferation of the adipose and connective tissues, probably in consequence of morbid nutrition. Clinical Experience.——Argentum nit. and Phosphorus are the only two remedies that have so far proved to be of any special value in this disease. Therapeutic Indications.—These will be found under the heads of myelitis and spinal sclerosis, which see. Consult, also, spinal hyperaemia and progressive muscular atrophy. Auxiliary Treatment.—Duchenne is said to have cured two cases of this disease with the induced current, but others have not been so fortunate. Improvement, however,-has fol- lowed the application of the primary current to the spine and the faradaic current to the affected muscles; in one case even where there were extreme atrophy of the extremities and absolute loss of muscular contractility to both currents, until after many weeks of constant eflbrt there was produced a slight reaction, followed by increasing improvement up to approxi- mate recovery. GLOSSO-LABIO-LARYNGEAL PARALYSIS. Synonyms.—-—Duchenne’s Disease, Labio-Glosso-Pharyn- geal Paralysis, Progressive Glosso-Labio-Laryngeal Paralysis, Progressive Bulbar Paralysis, Myelitis Bulbi; Fr., Paralysie ' Glosso-Labio-Laryngée ; Ger., Progressive Bulbarparalysie. Definition.—-An acute or chronic, progressive and sym- metrical paralysis of the lips and adjacent facial muscles, of the tongue, pharynx, and sometimes of the larynx, with or without conspicuous muscular atrophy. Diagnosis. —— Progressive muscular paralysis somejzimes 100 NERVOUS THERAPEUTIUS. resembles this disease, especially when the tongue is first involved, but that affection seldom commences in these parts, and never until after atrophy has set in. Facial paralysis might be carelessly mistaken for this disorder, but facial paralysis is confined to the parts animated by the facial nerve, whereas in this disease only the muscles of the lower part of the face are affected. Pathology:-The microscope shows that there is degenera- tion of the ganglion-cells in the motor nuclei of the hypo- glossus, portio-dura, spinal accessory and pneumogastric nerves, the nucleus of the cell being destroyed and its place supplied by numerous brown granules. Chronic sclerosing myelitis has also been observed at the'points of origin of these nerves, in the medula oblongata and upper part of the spinal cord, the nerve fibres being reduced in size and number, their contents in a state of fatty and granular degeneration, and the cylinder axis either atrophied or hypertrophied. The wasting of the ganglion cells is not always in proportion to the atrophy of the affected muscles, a fact which Duchenne and others attempt to explain by supposing that the ganglion cells in the motor nuclei are partly motor and partly trophic. Clinical EXperience.—AnacardtQ1/m and Argentum nit. are said to have cured bulbar paralysis, but I am obliged to con- fess that I have obtained but little benefit from either of these remedies in this formidable complaint. Baryta and Phos- phorus have also been recommended. I recently had an opportunity of trying Plwmbu/m., and for a time it seemed to arrest the progress of the disease, but finally neither it nor any other remedy seemed to do any material good. I am strongly of the opinion, however, that if the remedy had been given from the time the disease first made its appearance it would have proved more effective. Therapeutic Indications.-—-These will be found under the heads of myelitis and posterior spinal sclerosis, which see. Auxiliary Treatment.—But little can be done, in the way of accessory treatment, to benefit the patient. Electricity, though unsuccessful as a curative agent, has seemed to do somagood in lessening the suffering, especially in relieving ’ ‘.1 IO! ‘Q. I I PROGRESSIVE MUSCULAR ATROPHY. 101 the sense of constriction in the throat and chest. The food, which should be both nourishing and easily digestible, requires to be reduced to a semi-solid condition before any attempt is made at swallowing it. PROGRESSIVE MUSGULAR ATROPHY. Synonyms.——Wasting Palsy, Myopathic Paralysis, Amyo- trophic Paralysis, Gruveilhier’s Atrophy, Progressive Poly- myositis, Paralysis Atrophica; Fr., Atrophie Musealaire Grais- seuse Progressive, Paralysie Mnscalaire Progressive Atrophiqne ,- Gr., Muslcelatrophie, Maslcelliihmung. Definition.—A chronic wasting and degeneration of the muscular tissue, more especially of the muscles of the ex- tremities, in consequence of which there is a corresponding loss of motor power. Diag‘n0siS.—Progressive muscular atrophy is not easily mistaken for any other disease, as its slow progress and suc- cessive.implication of certain muscles and groups of muscles is very characteristic. There are forms of paralysis com- plicated with muscular atrophy, but in these cases the paraly- sis precedes the atrophy, while in progressive muscular atrophy the paresis, for it is mainly muscular weakness rather than paralysis, accompanies and keeps pace with the wasting of the' muscles. Path010gy.—The disease does not originate, as was formerly believed, in the muscles themselves, but in structural changes in the spinal cord. These changes consist chiefly in atrophic degenerations of the ganglion cells of the anterior horns of the gray matter from where the motor roots emerge which preside over the nutrition of the affected muscles. The muscular atrophy, though sometimes consisting only of simple atrophy without degeneration, is in the majority of cases accompanied by the fatty and granular forms of muscular degeneration, and in others by the waxy or vitreous. When the muscles of the face are involved, it gives rise to the affection known as labio- glosso-laryngeal paralysis. (For further information on this subject consult the author’s work on Diseases of the Nervous System, p. 179, et seq.) 102 NERvoUs THERAPEUTICS. Clinical Experience.—The remedies mostly to be relied upon ‘in this disease are: Plumbum, Phosphorus, Picric ac., Arsenicum, Sepia, Argentum nit., Cuprum and Lachesis. The following have also been recommended: Physostigma, Sulphur, Nux vom., Belladonna and Strychnia. Therapeutic Indications.-These will be found under the heads of myelitis and posterior spinal sclerosis, which see. Auxiliary Treatment.—The chief dependence is on central galvanization, with persistent and methodical Faradization and galvanization of the affected muscles. AMYOTROPHIG LATERAL SGLEROSIS. SynonymS.—Inflammation of the Lateral Columns, and of the Anterior Tract of Gray Matter, of the Cord; Fr., Sclérose Latérale Amyotrophigue; Ger., Amyotrophigue Lateralskler0sc des Rilckenmarks. Definition.—A form of spinal sclerosis in which the lateral columns of the cord are symmetrically sclerosed, and the anterior horns of gray matter symmetrically atrophied and degenerated, and which, beginning in the cervical portion of the cord, extends to the lumbar region, and finally proves fatal by implicating the medulla oblongata. Diagnosis;-—Amyotrophic lateral sclerosis differs from the spinal paralysis of adults, to which it bears some resemblance, not only by the greater intensity of its symptoms, but by the existence of both fibrillary twitching and spasmodic contrac- tions of the limbs, neither of which occurs in the latter disease. As for progressive muscular atrophy, of which it was formerly supposed to be a peculiar form, the muscular atrophy is never preceded by paralysis, as in amyotrophic lateral sclerosis; neither do spasmodic contractions occur in it, as they do in this disease. ~ Patho1ogy.—“ I propose,” says Charcot, who first separated this disease pathologically from progressive muscular atrophy, “to call that disease in which the two systems of the pyramidal fasciculi are affected, both in the cord and in the medulla oblongata, amyotropic lateral sclerosis; only the lesion cannot MULTIPLE SPINAL SCLEROSIS. 103 be followed upward ordinarily beyond the cerebral peduncle. The alteration reacts on the gray substance of the anterior cornua of the cord and on the analogous gray parts of the medulla oblongata; and it follows two methods. In certain regions it is a destructive lesion of the cellular elements. The consequence is, then, an atrophy of the muscles which are in relation with the nerves emanating from the diseased gray substance. In other parts it is a simple irritative functional lesion of the ganglionary elements. As a result, in the parts, besides the paralysis more or less pronounced, there is a notable exaggeration of the tendinous reflexions, and even, at a certain moment, a considerable contracture, occasionally, of the members. The contracture or, in its absence, the exag- geration of the tendinous and muscular reflexions distin- guishes clinically, according to my observation, this form of spinal muscular atrophy from that in which the cellular elements are destroyed without any participation of the white fasciculi.” ‘ Clinical Experience:-I am not able to give any satisfac- tory clinical experience pertaining to this disease, though what is said under this heading in regard to progressive muscular atrophy applies equally to this affection. Therapeutic Indications.——-These, so far as our present knowledge of the disease enables us to give them, will be found under the head of posterior spinal sclerosis, which see. Auxiliary Treatment.—We can add nothing of value to what has been said under this heading in the preceding article. MULTIPLE SPINAL SCLEROSIS. Syn0nyms.——Disseminated Spinal Sclerosis, Insular Spinal Sclerosis, Disseminated Multilocular Sclerosis; Fr., Sclérose en Plagues Disséminées ; Ger, Multiple Sklerose des Rilckenmarks. Definition.—A form of spinal sclerosis characterized by the presence of scattered patches of sclerosed tissue in the antero- lateral columns of the spinal cord, but not often confined to them. Diagnosis.—When the disease is confined to the lateral 104 NERVOUS THERAPEUTICS. columns of the cord there is nothing to distinguish it from the symmetrical form of spinal sclerosis next to be described, and when the posterior root-zones are implicated the symp- toms are similar to those of posterior spinal sclerosis or loco- motor ataxia; consequently it is impossible, in the present state of our knowledge, to diagnose the disease with certainty, unless the symptoms of both these conditions should happen to be united in the same case. Path0l0g‘y.———The distinctive pathological feature of this disease is the existence of masses of sclerosed tissue, varying from one to two lines in thickness, distributed through dif- ferent portions of the cord. They are not confined to any particular portion of it, though they are most frequently met with in the lateral columns. Examined with the microscope, the nerve-tubes of the white and the nerve-cells of the gray substance are found to have disappeared, or to have greatly diminished in number, and to have been replaced by prolif- eration of the connective-tissue element, the pressure of which upon the nerve-cells and tubes is the cause of their disin- tegration and wasting, the fluid portion undergoing fatty degeneration. Clinical Experience.—Plumbu/m, Alwminum, Phosphorus, Secale and Argentum mlt. are the principal remedies which have been given, with greater or less success, in the various forms of spinal sclerosis. Therapeutic Indications.——These will be given under the head of posterior spinal sclerosis, which see. Auxiliary Treatment.—-This is chiefly confined to preserv- ing, as far as possible, the general health of the patient. Electricity can be of but little use in these cases, though the primary galvanic current (constant) is said to be of some bene- fit in relieving the contractions. PRIMARY SPINAL SCLEROSIS. Syn0nyms.—Spasmodic Spinal Paralysis, Primary Lateral Sclerosis, Primary Symmetrical Lateral Sclerosis, Idiopathic Lateral Spinal Sclerosis, Paralysis Spinalis Spastica; Fr., PRIMARY SPINAL SCLEROSIS. T abes Dorsal Spasmodiqae; Ger., Spatisehe Spinalparalysie, Prirniire Lateralslelerose des Riiekenrnarks, Prirnéire Slclerose der Seitenstréinge des Riiclcenrnarlcs. Definition.——A spasmodic spinal paralysis, caused by a sym- metric and systematic primary sclerosis of the lateral columns of the cord. Diagn0Sis.——The disease can only be recognized by the characteristic symptoms, viz.: paralysis with contractions, but without conspicuous muscular atrophy, pain in the back and limbs, and the absence of any intracranial lesion capable of accounting for the disease as a secondary disorder. Hence the difficulty of distinguishing between the symptoms of this dis- ease and those of chronic spinal meningitis, multiple spinal sclerosis, and tumors pressing on the cord and giving rise to similar phenomena——a difficulty so great that, in the language of Dr. Hammond, I know of no sure sign by which, in the present state of our knowledge, the discrimination can be made. Path0l0g‘y.——The pathological changes observed in the spinal cord in this disease are in perfect harmony with the symptoms as interpreted by what is known concerning the physiological action of the different parts of the cord. Thus Charcot has shown that proliferation and hardening of the neuroglia, with simultaneous wasting of the nerve-cells and fibres (sclerosis), occurs to a greater extent in the cervical por- tion of the cord than elsewhere, the sclerosed condition, when this part is affected, extending as far as, and even beyond, the outer angle of the anterior horn of gray matter, while pos- teriorly it almost reaches the posterior tract of gray matter. As we descend the cord it becomes more and more circum- scribed, while at the same time it approaches closer and closer to the cortical layer, until in the lumbar portion of the cord it touches the cortical layer, and at the same time only occupies about one-fourth the area of the lateral columns. When it extends to the medulla oblongata it is confined to the anterior pyramids, and does not involve the nuclei of the bulbar nerves, as in the amyotrophic form of lateral spinal sclerosis. / 8 106 NERvoUs THERAPEUTICS. Clinical Experience.-—This does not differ from that of the other forms of spinal sclerosis already considered. Therapeutic Indications.--These will be given in detail under the head of posterior spinal sclerosis, which see. Auxiliary Treatment.—See previous articles under this heading. SECONDARY SPINAL SCLEROSIS. Syn0nyms.———Secondary Spinal Degeneration; Fr., Les Dé- générations Secondaires de la Mo'e'lle Epiniere ; Ger., Seconddre Er- krankung Einzelner Rilckenmarksstrdnge. Definiti0n.—-Secondary spinal sclerosis is a lesion which occurs in certain regions of the spinal cord, either as a result of some previous disease of the cord itself or as a consequence of intracranial disease. . Diagn0sis.—Charcot’s “ foot phenomenon,” Westphal’s “ ten- don reflex,” or knee phenomenon, and Onimus’s “associated movements” are usually relied upon as diagnostic signs of secondary degeneration of the cord. (See the author’s article 011 this subject in Arndt’s System of Medicine, Vol. II., p. 641.) Pathology-The degenerative changes in this disease are similar to those which have already been described as charac- terizing the various forms of sclerosis, viz.: atrophy and degeneration of nervous filaments, the formation of granular corpuscles in the degenerated tissue, and the proliferation of the neuroglia. When muscular atrophy is associated with the paralysis and contracture resulting from the sclerosed condi- tion of the cord, the anterior cornua are involved in the de- generative process, the nerve-cells undergoing more or less disintegration and wasting. Clinical Experience.-—’l‘his is similar to that of other forms of spinal sclerosis already described. Therapeutic Indications.—-These will be given in full under the head of posterior spinal sclerosis or locomotor ataxia, which see. Auxiliary Treatment.—See above reference. POSTERICR SPINAL SCLEROSIS. 107 POSTERIOR SPINAL SCLEROSIS. Synonyms.—-Locomotor Ataxy, Progressive Locomotor Ataxia, Sclerosis of the Columns of Burdach, Tabes Dorsalis; Fr., Ataxie Locomotrice; G’er., Graue Degeneration der Hinter- strdnge des Ritckenmarks. Definition.—A form of spinal sclerosis involving the poste- rior root-zones of the spinal cord, characterized by loss of power of coordinating movements, whereby voluntary movements, and especially those concerned in walking, are rendered more or less unsteady. Diagn0Sis.——When the characteristic symptoms are present, such as fulgurant pains, paraesthesia in the extremities, marked staggering on closing the eyes, the girdle sensation, the general lack of precision of movements, visual disturbances, etc., and, especially, loss of deep reflexes, the diagnosis is sufliciently clear; but when only two or three of them are present the dis- ease is liable to be mistaken for mere functional disturbances producing ataxia. In estimating individual symptoms, we should remember (1) that sclerosis of the posterior columns always begins with sensory disturbances; (2) that the pains are fulgurant, intermittent and of irregular occurrence; (3) that they may be located in any part of the body, as the limbs, face, back, viscera; (4) that they precede the motor disturbances by months or years; (5) that they may for an indefinite period constitute the only symptoms of the disease; (6) that the con- tinuance of the first stage, previous to the appearance of the ataxia, is usually about three years, though often not more than one, and sometimes as many as five; (7) that during this stage the patient may enjoy excellent health, though occasion- ally marked, perhaps, by slight functional disturbances, ocular, arthritic, etc., which scarcely attract attention; at last (8) ataxia, with the more prominent symptoms of the second stage, makes its appearance, and then, if not before, the disease is clearly recognized. In order to render the diagnosis more certain, tests may be made by means of the various reflex and associated movements referred to under the head of secondary spinal sclerosis, which see. 108 mcnvous THERAPEUTICS. Pathology.--The pathological alterations consist in a pecu- liar degeneration, with subsequent atrophy and hardening of the posterior columns of the cord and the posterior roots of the spinal nerves. The white substance of the cord is converted into a grayish softened mass. The microscope shows few nerve filaments, granular cells, fatty molecules and corpora amylacea imbedded, as it were, in a matrix of sclerosed tissue, the result of proliferation of the neuroglia or connective tissue element. The diseased cord ultimately shrinks and indurates, constituting real atrophy of its essential constituents. Clinical Experience.-—The remedies which have been found to be of the greatest value in this disease belong mostly to the mineral class. They are: Plumbum, Aurum met, Aurum rnur., Aurum cyan., Phosphorus, Argentum nit , Zincum met. and sulph., Alumina, Physostigma, Gelsemium, Belladonna, Lathyrus cic., i/Esculus hip., Baryta carb., Angustura, the last three, espe- cially, for the fulgurant pains. Therapeutic Indications.—Plumbum.--'l‘his remedy pro- duces the anatomical lesions of disseminated sclerosis, the tremor, the paralysis and the muscular atrophies, and it has repeatedly cured these symptoms. AuruIn.—This metal and its preparations, the muriate and cyanate, have repeatedly cured both the fulgurating pains and the ataxia; weakness and paralytic feeling chiefly noticed when walking; amaurotic blur before the eyes. Alumina.——Pain and paralysis of the lower extremities; impossible to walk with the eyes closed; soles of the feet feel as if they were swollen and too soft; numbness of the heels when stepping on them; when Walking he staggers and is compelled to sit down. Phosphorus.—Sexual irritation; involuntary sexual emis- sions; great irritability and nervousness; paralytic feeling in the feet and limbs, with trembling of the knees; pains darting from the hip-j oint; anaesthesia, with increased heat; periodically returning insupportable pains in the spine, preventing walking; pain and tenderness in the soles of the feet. This remedy is suited to every stage of the complaint; the fulgurating pains and visual disturbances of the first, the ataxic symptoms and POSTERIOR srman scnnnosrs. 109 genital excitement of the second, and the paralytic, atrophic and degenerative condition of the last. Argentum nit.—Vertigo as if turning in a circle, preventing standing; momentary blindness; irregular movements of the extremities; limbs retracted toward the abdomen; instability of the limbs; vacillating gait; cannot walk in the dark without staggering. I once cured a well marked case of posterior spinal sclerosis with this remedy after the ataxic symptoms had set in. Zincum.-—Great weakness in the lumbar region and in the knees when walking; weakness, numbness and tremor in the limbs; lancinating pains extending to the knees, which feel as if they would give way; paralysis of the bladder. Phys0stigma.——Feeling of unsteadiness and insecurity in walking; has to tread carefully, especially if the eyes are shut or when in the dark; feels the need of a cane or some other means of support; feeling of weakness, as though paralyzed, passes downward through the whole length of the spine to the lower extremities, which feel as if asleep; staggering gait, as if drunk. ' Lathyrus cic.——Weakness and trembling of the limbs, followed by a sort of stupefaction ; almost total loss of power in the extrem- ities; pigs that eat it are said to drag their feet after them. Gelsemium.—Paralysis of all the li1nbs; cannot move them, they feel so heavy; electric-like pains through the limbs; un- steady gait; muscles will not obey the will; sense of helpless- ness fro1n brain-weakness; temporary blindness; paralysis of the bladder. Belladonna.-—Loss of power to coordinate muscular move- ments; when walking he raises his feet slowly and puts them down with force; trembling of the muscles and limbs; weak and tottering gait; paralytic weakness of all the muscles, especially of the feet; paralysis of the motor ocali; fnlgnrating pains; especially valuable during the initial period of the disease. Helleb0rus.—Muscles do not act in harmony unless the attention is fixed upon them; walk slow and tottering; twitch- ing, tearing pains in the limbs; sudden relaxation of certain 110 NERvoUs THERAPEUTICS. muscles; he lets fall an object held in the hand; staggering gait, with want of firmness in the legs and bending of the knees; vesical tenesmus ; impotence, with flaccid penis. Esculus hip.—Lameness and paralytic feeling from neck down; back and legs weak, can hardly walk, must lie down; fulgurant pains; ocular and vesical tabetic symptoms. This remedy is indicated even when the sclerosis is well advanced. Ignatia.—Weakness and trembling in the limbs; he was unable to walk, but was obliged to remain sitting, because when walking the knee was involuntarily drawn upward. Baryta carb.-—-When standing he felt a blow in the thigh, above the right knee, so violent that he believed he would fall forward; in the right knee a rapid momentary pain, like cutting with a knife, which makes the leg lame; trembling of the hands and limbs; great mental and bodily weakness; constant inclination to lie down. Angustura.—Twitching and jerking along the back like electric shocks; paralytic weakness of the whole body; in- dicated in the spasmodic form, or when the paresis is associated with fulgurant pains. Silicea.—Trembling in the limbs, as if he had lost all power over them; wandering pains, passing quickly from one part of the body to another; sense of great debility, wants to lie down; limbs sore, lame and cold, go to sleep easily; paralytic weakness in the joints when sitting or walking; drawing, jerking pain in the hip-joint; tearing pains in the thighs, followed by numbness. Oxalic ac.——Pains shooting down fro1n the spinal cord to the limbs, especially the lower ones; back feels too weak to support the body; dyspnoea, followed by general numbness; jerking pains, confined to small spots and lasting only a moment. Nux vom.—Staggering walk; when he walks he drags his feet; numbness and deadness of the legs and feet; incomplete paralysis, with the power of motion not entirely gone; paralysis of the bladder; obstinate constipation. Auxiliary Treatment.—The operation of nerve-stretching has, until very recently, been regarded as an efficient means of rosrnnron SPINAL SCLEROSIS. 111 relieving the most distressing symptoms of locomotor ataxia, but at present the consensus of opinion on the subject among those whose opportunities of forming a correct estimate of its value in this disease are the greatest, is, that it is doubtful whether any marked symptoms have been permanently re- lieved by it. Karl Pauli highly recommends the lukewarm baths introduced by Westphal as the best way of relieving the fulgurating pains, employing them almost constantly for weeks, or until the pains subside. Both Mochoukowsky and Charcot speak very highly of the treatment by suspension. The former, who was the originator of the treatment, makes use of the apparatus of Dr. Sayre, of New York, the suspension at first being of only half a minute duration; this is gradually increased to three minutes, the maximum not exceeding four minutes. Treatment every other day suffices, no benefit accruing from its daily practice. Charcot finds that after twenty or thirty treatments Romberg’s symptom disappears, followed by amelioration of the urinary and vesical symptoms; in a number of cases the plantar anaes- thesia passed off. Other experiments, however, have been less successful with this mode of treatment, one case resulting, after two suspensions, in spasmodic paraplegia, which disappeared again after three days. After all, however, we find that the most efficient agent in ameliorating the symptoms during the initial stage is electricity. Usually the positive pole of the galvanic current is placed on the nape of the neck and the negative sponge swept up and down the spine and limbs. Of late, Rumpf’s treatment with the electric brush——the rapidly interrupted Faradaic current , —-along the back and legs, has seemed to do the most good, and almost entirely superseded every other form. The anode is applied to the sternum, and the cathode energetically carried over the spine and extremities until the surface turns to a deep red, each séance lasting ten minutes. 112 NERVOUS THERAPEUTICS. SPINAL TUMORS AND OTHER ABNORMAL GR OWTHS. Synonyms:-Meningeal and Intramedullary Spinal Tu- mors; Fr., Tumeurs Rachidiennes, Tameurs de la Moelle Elpiniere; Ger, Kranlchafte Geschwitlste des Rilclcenmarks. Definiti0n.—Tumors, foreign growths and adventitious products within the spinal canal. Diagn0sis.——The diagnosis is necessarily more or less un- certain, since the same symptoms may be produced by very different causes. Most cases, however, are attended by one or more of the following characteristics: (1) a very gradual onset of the symptoms; (2) exacerbations and remissions correspond- ing to changes in the size and vascularity of the tumor or other growth; (3) symptoms depending on the seat and cir- cumscribed character of the lesion; and (4) the presence or absence of any other disease of the part capable of producing the symptoms. The nature of the foreign growth is, as a rule, still more difficult to determine. When the patient exhibits unmistakable signs of a scrofulous, syphilitic or cancerous dyscrasia, the presumption will be in favor of its belonging to the prevailing diathesis. Some light may also be thrown upon the subject by the presence of tumors elsewhere. Clinical Experience.-—This does not differ materially from the clinical experience given under the head of cerebral tumors, which see. Therapeutic Indications.—-These will be found under spi- nal meningitis, myelitis, acute ascending paralysis and other forms of paraplegia, which see. Auxiliary Treatment.—In cases of debility, and especially when of a scrofulous, syphilitic or cancerous nature, the vital power should be raised, the nutritive functions improved, and_ the patient kept under the most favorable hygienic conditions. SPINAL GONGUSSION. Synonyms.— Concussion of the Spinal Cord, Commotio Medulla’ Spinalis; Fr., Commotion Spinale, Commotion de la Moelle Epiniere; Ger, Erschiitterung des Ritclcenmarlcs. SPINAL conoussron. 113 Definition.——A shock communicated to the spinal cord and interfering with its functions. Diagn0sis.—-In the absence of definite paralysis it is often necessary, in order to ascertain whether any organic lesion has taken place, to wait until sufficient time has elapsed after the accident to determine that question. This is the more neces- sary because meningitis, myelitis and anaemia of the cord are liable, sooner or later, to result from spinal concussion. These results, when present, will of course manifest themselves by their characteristic symptoms; but it should be remem- bered that several weeks may elapse after the injury before spinal symptoms are developed. Moreover, the difficulty of forming a correct estimate of the nature and extent of the spinal injury is greatly enhanced, in many cases, by the dis- position of the patient and his friends—we refer especially to railroad accidents—to exaggerate the symptoms, either in consequence of their excited imagination or from interested motives, the question of pecuniary damage being in many instances an important factor in the diagnosis. The physi- cian owes it to himself, no less than to others, to exercise the utmost care and intelligence in coming to a correct conclusion in such cases. Pathology:-On this subject Erichsen, the leading writer on concussion of the spine, says: “We should be taking a very limited view of the pathology of concussion of the spine if we were to refer all the symptoms, primary and remote, to inflammatory conditions, either of the vertebral column, the sheaths of the spinal nerves, the meninges of the cord, or the substance of the medulla itself. Important and marked as may be the symptoms that are referable to such lesions as these, there are undoubtedly states, both local and constitutional, that are primarily dependent on molecular changes in the cord itself, or on spinal anaemia induced by the shock of the accident either directly on the cord itself, or indirectly, and at a later date through the medium of the sympathetic, in consequence of’ which the blood distribution to the cord be- comes disturbed and diminished.” Clinical Experience.—(/‘alendala, Hypericum, Arnica, Rhus 114 NERvoUs THERAPEUTICS. tox., Conium, Cicuta, Sulphuric ac. and Hepar sulph. are among the leading remedies resorted to in this condition, the first three being prescribed immediately after the accident, both internally and locally. Therapeutic Indicati0ns.—These will mostly be found under spinal hyperxmia, anwmia, haemorrhage, myelitis, menin- gitis, paralysis and sclerosis, which see. We shall here confine ourselves to those above mentioned. Hyperi0um.—Crreat nervous depression following spinal con- cussion; vertebrae very sensitive to the touch; inability to walk after the injury, especially when the attempt is accompa- nied by violent pains; retention of urine, with shuddering and desire to urinate. Calendula.-—Traumatic cases, with stinging pains at the seat of injury; the patient is very uneasy in every position; great tendency to start, especially on hearing a noise; the in- jured part becomes red and inflamed; shuddering in the back; frequent micturition. Arnica.——Spinal concussion attended by intrarachidian haemorrhage; limbs cold, pulse slow and weak, and sickness of the stomach; paresis, with or without numbness of the limbs; pain aggravated by movement; symptoms better by lying quiet. Rhus tox.-——Paralysis, following spinal concussion; extreme coldness of the hands and feet; muscular startings and twitchings; pains and numbness in the paralyzed limbs. Cicuta.—Paralysis, with insensibility; convulsive twitchings of the muscles; coldness of the body, with an excited and apprehensive state of the mind; irritability of the bladder; constipation. Sulph. ac.—Weakness in the back and lower extremities so great as to prevent standing without support; shooting pains in the limbs, with trembling of the whole body; violent press- ure on the neck of the bladder, with retention of urine. Conium.—Spinal concussion attended by a sensation of numbness in the paralyzed parts; sensation in the limbs as if they were surrounded by tight bands. Hepar sulph.—Great weakness of the limbs, with nervous I SPINAL coucossrou. 115 depression ; shiverings from below upward ;‘ very excited and irritable; nervous trembling; weakness of the bladder, with involuntary discharges of urine. Auxiliary Treatment.—If reactive fever sets in, accompa- nied by much pain in the back, ice or ice-water should be applied to the spine, for which purpose Chapman’s rubber- bags will be found convenient. If necessary, the temperature of the body, and especially of the extremities, should be raised and maintained at the normal standard by artificial means. The continuous galvanic current will be found beneficial in hyperaesthetic states of the spinal cord. Cold salt-water douches and the shower-bath will sometimes prove useful in advanced cases. In most cases perfect rest in the recumbent position will be required for some time after the accident. Unless the shock is a very severe one, these measures, with rest and sleep, plenty of fresh air and a simple, nutritious diet, will be suffi- cient in most cases to restore the patient to health; but care must be taken not to permit any exercise until after the nerv- ous system has recovered from its enfeebled and exhausted state; then the patient will often be benefited by a change of air and scene. PART III. CEREBRO-SPINAL DISEASES. GEREBRO-SPINAL HYPEREMIA. Synonyms. — Cerebro-spinal‘ Congestion; Fr., Congestion Cérébro-spinale, Hyperémie Cérébro-spinale; Ger., Cerebro-spinale Hyperitmie. Definition.—A simultaneous excess of blood in any portion of both the cerebral and spinal tissues. Diagnosis.—Cerebro-spinal congestion is not usually recog- nized as a distinct affection, partly because it is partial rather than general, and partly because it is most frequently a symp- tom of some other disease. Those cases usually regarded as belonging to the convulsive form of cerebral congestion, but unattended by loss of consciousness, are of this character. The characteristic symptom is stiffness and aching in the back part of the head and neck, which may subsequently develop into epileptiform convulsions, or into a tonic contraction of the extensor muscles of the spine. Path0logy.—The congestion is usually limited to the base of the brain and upper portion of the spinal cord. The con- vulsive action is due to implication of the medulla oblongata, and when the cerebral hemispheres are involved there is also, in most cases, loss of consciousness. Clinical Experience.—— Gelsemium and Cimicifuga are the two leading remedies in this disease, and are almost infallible. Belladonna, Natrum brom., Kali brom. and Passijlora incar. are also useful remedies, especially the last. Therapeutic Indications. ——These are given under the heads of cerebral and spinal hyperamia, which see. (116) NEURASTHENIA. 117 NEURASTHENIA. Syn0nyms.—Nervous Exhaustion, Nervous Debility, Brain Fag, Gerebro-spinal Anaemia, Cerebrasthenia et Myelasthenia; Fr., Anémie C’e’re’bro-spinale; G'er., Oerebro-spinale Antimie. Definition.——A functional disease affecting the whole nerv- ous system, both cerebro-spinal and sympathetic, and marked not only by great mental and physical debility, but by other well-defined, but constantly varying symptoms, which appear and disappear suddenly without any regular order of suc- cession. Diagnosis.--The disease is liable to be confounded with anaemia and hysteria. The following tables, prepared by Dr. Beard, give the differential diagnoses between them : Neurasthenia. General Anaemia. Chiefly found in nervous diathesis. Impoverishment of nervous system ; no necessary anaemia. Patient may be plethoric. Found chiefly between the age of fifteen and sixty. Not at all necessarily dependent on any important recognizable organic dis- ease. Pulse may be full or normal, but some- times very rapid or very slow. No cardiac murmurs. N o pallor, sometimes even a rubicund appearance. Easily fatigued by exertion; mental labor in cerebrasthenia more ex- hausting than physical. Memory often temporarily weakened, and consecutive thought and sustained mental activity frequently impos- sible, even when prolonged muscu- lar labor causes little or no fatigue. Appears also in the tuberculous, or rheumatic, or other diathesis. Impoverishment of the blood; increase of water and diminution of the red corpuscles. Found in all periods of life, from ex- treme infancy to old age. More frequently, though not necessa- rily, associated with some organic disease, as tuberculosis, carcinoma, Bright’s disease, etc. Pulse small, weak and compressible. Murmur at the base of the heart and over the large arteries, as the ca- rotid, subclavian, etc. Very perceptible pallor of the face, especially of the lips. Easily fatigued by exertion; physical labor always more exhausting than mental. 118 NERVOUS THERAPEUTICS. Neurasthenia. General Anaemia. Insomnia a very frequent complication. No necessary or constant disturbance of the circulation. Habitual mental depression. Though common to both sexes, not so relatively frequent in females. Usually recovers, but gradually, under the influence of rest and nutritious food. Insomnia not so frequent a complica- tion; frequently an abnormal ten- dency to sleep by day as well as by night. Disturbance of the circulation, with habitually cold extremities. Mental depression not so frequent. Far more frequent in females. May be rapidly removed by the removal of the organic cause. Neurasthenia. Hysteria. No convulsions or paroxysms. N o globus hystericus, no anaesthesia of the epiglottis, ovarian tenderness less common, and attacks of anaes- thesia far less frequent and less permanent. Symptoms more moderate, quiet, sub- dued and passive. May occur in well-balanced, intellect- ual organizations. Very common in males, though more common in females. Is always associated with physical de- bility. Never recovers suddenly, but always gradually, and under the combined influences of hygiene and objective treatment. Hysterical convulsions and paroxysms. Globus hystericus, anaesthesia of the epiglottis, ovarian tenderness and attacks of general or local anaes- thesia. Symptoms acute, intense, violent and positive. Usually associated with great emotional activity and unbalanced mental or- ganization. Very rare in males. In the mental or psychical form, occurs in those in perfect health. May recover suddenly and under purely emotional treatment. Path0l0g'y.—General neurasthenia was formerly, and by many still is, regarded pathologically as a form of cerebro- spinal anaemia. Its resemblance to spinal irritation, which is generally regarded as a form of spinal anaemia, is most strik- ing. The functional disturbances are not only equally great and varied, but even the characteristic spinal tendency is sometimes present. I am, therefore, disposed to regard the NEURASTHENIA. 119 disease as consisting essentially in a fluctuating local or partial anaemia of the great nerve-centres, in which the quantity and not, as in general anaemia, the quality of the blood circulating in the part is at fault. Clinical Experience.—The favorite remedies for this dis- ease appear to be; Phosphorus, Chininum sulph., Strychnia, Phos- phoric ac., Erythroxylon coca, Nux vom., Picric ac., Zincum brom., Zincum pic. and Avena sat. Many other remedies, however, have been employed with benefit in different cases; indeed, almost every remedy in the materia medica may be called for at one time or another, so variable and peculiar are the symptoms. Therapeutic Indications.-Phosphorus.-Great heaviness and weariness from the least exertion; extreme mental and physical prostration; bruised feeling in the back and limbs; myelasthenia. Chininum sulph.—Neurasthenia following severe and exhaust- ing illness, loss of vital fluids, or overexertion, either bodily or mental; nervous trembling; weakness and trembling of the lower limbs; coldness of the extremities. Erythroxylon.-——General nervous debility, the slightest exer- tion being attended by fatigue; mental depression, with anxiety and palpitation of the heart; oppression of breathing arising from nervous debility; sleeplessness and disinclination to work or move about; constipation, with abdominal disten- sion; fainting spells from nervous weakness; coldness of the limbs. Arsenicum.-—Constant disposition to lie down; sensation of weakness in the small of the back; weakness of the lower limbs, preceded or accompanied by copious watery stools; trembling of the limbs from debility; thirst for small quantities of water; sleeplessness and restlessness, especially at night. Galcarea ph0s.——Nervous prostration, with great depression of spirits; sore, bruised feeling in the back, with inclination to lie upon it; coldness and weakness of the lower limbs from defective circulation in them. Strychnia phos.—Aching pain, sometimes burning, extending from the back to the front of the chest, causing a feeling of 120 xnnvous THERAPEUTICS. nausea and anxiety; tenderness on pressure over the dorsal region; sleeplessness; cold feet, covered with clammy perspira- tion; great weakness of the lower lirn bs from exhaustion of the spinal motor nerve-cells ,- myelasthenia. Avena sat.—Neurasthe/nia of business and professional men, teachers, and women who have become exhausted by household cares and worry; coldness of different parts of the body de- pending on weakness of the circulation from lack of nerve force; cerebrasthenia. Nux Vom.—Nervous debility arising from debauchery and dissipation, late hours, high-seasoned food and abuse of ardent spirits; mental exhaustion of students and professional men; insomnia produced by overwork, business cares, etc. Indi- cated in all cases where there are a. disordered stomach and constipation. Zincum.-Chronic cases, attended by great mental and bodily depression; headache produced by mental exertion; loss of memory; cold extremities, with paralytic weakness; frightful dreams. Staphisagria.-—Nervous exhaustion caused by excessive sexual indulgence, onanism or loss of vital fluids; great mental de- pression; nocturnal emissions followed by great prostration; headache, backache and loss of memory, with inability to per- form either mental or physical labor. Epiphegus.-—Nausea and general languor; severe pain in the forehead caused by any unusual demand upon the system; aggravated by rising and going about, always better by rest in a supine position and by sleep. Zincum brom.— Cerebrasthenia caused by anaemia; mental and bodily weakness, with tendency to paralysis of the lower ex- tremities. This remedy is preferable to Zinc alone, as it has a quicker action and is more readily absorbed. Picric ac.—Hale regards this as one of our best restoratives of a wasted and worn-out nervous system; the least mental or physical effort exhausts the patient and brings on headache; homoeopathic to the brain-fag of students, school-girls and literary or business men and women. Zincum picr.— Cerebrasthenia and nervous exhaustion from NEURASTHENIA. 121 overworked brain or from sexual excesses; profound neuras- thenia, when the -nervous exhaustion has passed beyond the stage of erethism, seminal emissions or erotomania. Galois hypophos.-—-Neurasthenia attended by profuse night- sweats; sleeplessness, depression of spirits, loss of appetite, emaciation; pale and haggard look; habitual coldness and venus congestion of the limbs from debility; loss of virile power. Ignatia.—-Oppression of the chest and breathing from weak- ness; weakness of memory; depression of spirits; disposed to weep from the most trifling causes; loss of appetite, with feel- ing of repletion after swallowing a mouthful or two; palpita- tion of the heart on rising in the morning or after eating; complete absence of the sexual desire; face wan and pale; sleepless and full of fanciful apprehensions. Phosphoric ac.-—General debility, with feeling of extreme weakness and prostration; cold sweats during the day or on making any physical exertion; loss of all virile power; profuse night-sweats, followed by chilliness; mentally as well as physically depressed. Zincum phos.—According to Hammond, who first introduced the remedy, it is homoeopathic to mental depression, debility and nervous weakness, since in large doses it removes these symptoms when caused by cerebral congestion. Small closes, on the other hand, have in our experience frequently relieved these symptoms when dependent on cerebral anaemia. Pl1ysostigma.——Irritable spine, nervous headache and mental em- haustion; eyes feel weak and swollen; smarting, sore feeling on the tip of the tongue which feels as if scalded; aversion to cold water; mental exertion tends to produce nausea. Consult, also, spinal anaemia and spinal irritation. Auxiliary Treatment.-—-One of my city patients who was gradually recovering from a severe attack of neurasthenia, attended with aphonia, was induced during the recent Brown- Sequard craze, to submit to repeated hypodermic injections of his so-called “vitalizing fluid.” At first the patient seemed to be benefited, as he speedily recovered his voice, but reaction setting in he again lost it, and his subsequent recovery was 9 122 NERvoUs THERAPEUTICS. manifestly greatly retarded by the absurd “scientific treat- ment” to which he had been thus subjected. This remedy (I), which at best is nothing more than a mechanical stimulant, is liable to give rise to septic poisoning or tubercular infec- tion, and ought never to be sanctioned in these cases even as an auxiliary proceeding. As a general rule, patients suffering with this disease will soonest recover by following closely what is known as the \Veir Mitchell method of treatment. This consists (1) in per- fect rest, both mental and physical; (2) the acceleration of muscular waste, and the consequent ability of assimilating a greater amount of food, by massage of the muscles by a trained shampooéér, and by muscular contraction produced by Faradization; and (3) by supplying the waste so produced by regular and high feeding, so that the whole system, and the nervous system in particular, shall be abundantly nourished. The diet is to be increased and strengthened from day to day as this process goes on, until at last the patient is able to take, “in addition to two quarts of milk daily, three full meals, viz.: breakfast, consisting ‘of a plate of porridge and cream, fish or bacon, toast and tea, coffee and cocoa; a luncheon at 1 P.M. of fish, cutlets or joints, stewed fruit or cream, or a pudding; dinner at 7 P.M., consisting of soup, fish, joint and sweets; and, in addition, a cup of raw meat soup at 7 A,M. and 11 P.M. Should there be an occasional attack of dyspepsia, which rarely happens, it is at once relieved by keeping the patient on milk alone for twenty-four hours. The raw meat soup is made as follows: Take one pound of raw fillet of beef, chop it finely and place it in a bottle with a pint of water and five drops of hydrochloric acid. Stand the mix- ture in ice all night, and in the morning set the bottle in a pan of water at 110° F., and keep it two hours at this tempera- ture. It is then to be thrown on a stout cloth, and strained until the remaining mass is nearly dry. The filtered liquid is given in two or three doses in the course of twenty-four hours.” To give the soup the flavor of cooked meat, the beef to be used may be quickly roasted on one side, and then the process completed as above described. CEREBRO-SPINAL MENINGITIS. 123 CEREBRO-SPINAL MENINGITIS. Synonyms.—-Epidemic Meningitis, Cerebro-spinal Fever, Spotted Fever, Epidemic Cerebro-spinal Meningitis; Fr., Min- ingite Cérébro-spinale Epidémigue Méningite Ce’re’bro-rachidienne; Ger., Cerebral-Typhus, Epidemische-Meningite, Genie/ckrampft Ge- nickstarre. Definiti0n.—An acute epidemic febrile disease, depending on a diffusive inflammation of the pia mater of the brain and spinal cord, and characterized by sudden invasion, with ex- treme nervous shock, followed by vomiting, fever, violent headache, extreme prostration, great restlessness, excessive pain referred to the back of the head and spine, spasmodic contraction of the spinal extensor muscles, excessive cutaneous sensibility and frequent delirium, and accompanied by pur- puric and other eruptions on the face and limbs. Diag'n0sis.—The disease is liable to be mistaken for typhus fever, purpura haemorrhagica and malignant scarlatina. From the first it may generally be distinguished by the sudden appearance of the rash, without any previous mottling of the skin, and by the nervous symptoms above noted; from pur- pura heemorrhagica, by the intensity of the fever and the peculiar nervous symptoms; and from malignant scarlatina, by the characteristic rash, sore throat and other symptoms of that disease. Pathology.--The inflammation of the pia results in an exudation of purulent matter, which is deposited both at the base and onthe convexity of the brain, in its various depres- sions, and along the course of its great vessels, on the pons varolii and cerebellum, and on the posterior surface of the spinal cord, especially in the lumbar region. The cerebral membranes are all more or less injected; and the arachnoid is rendered opaque by the puruloid exudations before men- tioned, which vary in consistence from a thin.milklike lymph to thick and dense fibrino-purulent deposits. The brain sub- stance itself is more or less injected, and sometimes small spots of secondary softening occur, but in other respects the organ usually presents a normal appearance. The disease, therefore, 124 NERVOUS THERAPEUTICS. is a cerebro-spinal meningitis, of a specific, infective character, originating probably in a disease-germ, the nature of which is at present unknown. Clinical Experience.-—The remedies of greatest clinical reputation in this disease are Gelsemium and Cimimjuga. Aconite, Veratrum oir., Belladonna, Opium and Digitalis are also frequently prescribed. Baptisia, Rhus to:c., Apis, Hyoscyamus, Stramonium, Bryonia, Nurc vom., Arsenicum, Arum tri., Kali brom., Amm. brom., Cicuta, Agaricus, Cannabis ind., Caprum acet., Lachesis, Crotalus, Lachnanthes and Cactus have all been used with more or less benefit in particular cases. Therapeutic Indications.— Gelsemium.- Intense cerebro- spinal congestion, preceded by a severe chill; nausea and vomiting, followed by great depression, with dulness of speech, livid cheeks, dilated pupils, icy ‘coldness of hands and feet, extreme prostration, very weak pulse and laborious breathing; general muscular weakness, without any impairment of the mental power; somnolency and coma; sweating relieves. Cimicifuga.——Pain in the neck, shoulders and spine, also in the head, but not very violent, except perhaps in the top and back; low, restless, excitable delirium, like that of delirium tremens; eyes painful and sensitive to pressure; pupils dilated; general prostration, accompanied with more or less vomiting; tongue swollen and throat dry, causing a constant desire to swallow; muscular twitchings in various parts of the body; profuse cold sweat and very quick pulse. Veratrum ViI'.—-Severe pain in the neck and shoulders; vertigo, with dimness of sight, dilated pupils and vomiting; loss of consciousness, with coldness of the body, irregular and feeble pulse and great prostration ; convulsive twitchings; tonic contraction of the extensor muscles of the spine; pulse frequent and feeble; trembling of the whole body. ()pium.—Somnolency, or a tendency to stupor, with or with- out delirium; face bloated and muscles relaxed; head and limbs feel cold, numb and heavy; eyes fixed and half closed; opisthotonos, with constrictive feeling in the chest and diffi- culty of breathing; vomiting, colic, diarrhoea or constipation ; abdomen hard and swollen; spasmodic jerkings of the limbs; cold perspiration; coma; worse when sweating. CEREBRO-SPINAL MENINGI'l‘IS. 125 Digitalis.—Stiffness in the back and side of the neck; sharp stitches and severe cutting pains in the nape of the neck; heart’s action slow, irregular and labored; head tends to fall backward when raised up or sitting; violent lancinating pains in the head, especially in the occiput; delirium resembling that of delirium tremens (Cimicifuga); depression accom- panied by faintness and vomiting; convulsions, with retrac- tion of the head; syncope, with coldness and tendency to collapse. ‘ Aconite.—In cases where there is well-marked reactionary fever, attended by chilliness, thirst, restlessness, dryness of the skin and anxiety of mind. Baptisia.-—Typhoid symptoms, accompanied by a bruised and painful feeling in the back of the head and neck; body feels stifi’ and sore all over ; dark, livid spots on the skin; great rest- lessness, especially of the head and limbs, which are in con- stant motion; stomach sore and sensitive to pressure; Vertigo; weakness and trembling of the limbs. Apis mel.—Pain and stiffness in the back of the neck; burning and throbbing in the head; stabbing pains in the occiput; great mental and bodily prostration, with sense of suffocation; swelling of the face, giving it an oedematous ap- pearance; hyperaesthesia of the skin, with stinging pains all over the surface; great oppression of breathing, feels as though he would suflbcate; pulse variable and intermitting; dimness of sight; urine scanty or suppressed. Cicuta.-—Vertigo, with moaning delirium; head retracted; muscles of the neck sore and stiff; anxious expression of countenance; dilated pupils; double vision; tonic contraction of the spinal extensor muscles, especially those of the neck; opisthotonos ; spasmodic action of the muscles of the face and limbs; convulsions attended with cries, working of the jaws, distortion of the limbs, spasm of the muscles of the chest, painful distension of the abdomen, followed by insensibility and immobility; pain in the stomach and vomiting; ashy hue of the skin; diarrhoea or constipation; general pa- ralysis. Hyoscyamus.—Drawing pain in the neck when turning the 126 NERvoUs THERAPEUTICS. head; violent headache, alternating with pains in the back of the neck; throbbing sensation in the brain; heaviness of the head, with dimness of vision, palsy of the tongue, and small, quick and intermitting pulse; stiffness of cervical muscles and trismus; spasms of the chest, with temporary arrest of breath- ing; epileptiform convulsions; jerking of the limbs; constant grinding of the teeth; brown spots, large pustules and gangre- nous vesicles on the skin; relaxation of the lower sphincters, with involuntary evacuations. Cannabis ind.——Pain in the back of the head and across the shoulders and spine; fixed, staring eyes, with dilated pupils; vertigo on rising; hearing unusually acute; emprosthotonos or opisthotonos, with loss of consciousness; face cold, with drowsy and stupid expression of countenance; great oppression of the chest; pulse feeble and irregular; collapse, with pale, clammy and insensible skin. Hydrocyanic ac.--Malignant cases, attended with immediate collapse; protruded half-open eyes; dilated and insensible pupils; bloated and bluish face; eyes insensible to light; tongue protruded and paralyzed; feeble, irregular pulse and respiration; general coldness; involuntary evacuations of faeces and urine. I Veratrum alb.—-Stiffness of the neck, with bursting sensation in the head and choking in the throat; violent headache, with delirium; vomiting, with convulsive shocks in the head as soon as it is raised up ; head thrown back and rolling from side to side; face pale, cold and cadaverous looking; convul- sions, with loss of sense and motion; watery diarrhoea, attended by collapse; coldness and numbness of the limbs. Ph0sphorus.——Headache, with burning and stinging pains in the occiput; laming pains in the spine; dulness of hearing; frequent fainting; great prostration; petechial and purpuric eruptions on the surface of the limbs or body; tingling and tearing pains in the limbs; difficulty of breathing. Nux Vom.—Hyperaesthetic condition of the cerebro-spinal system of nerves; shocks in the brain; scalp sensitive to the touch; loud, reverberating sounds in the ears; oversensitive- ness to odors; stitching pains through the body; convulsions CEREBRO-SPINAL MENINGITIS. 127 renewed by the least touch; conscious opisthotonos; bruised sensation in the head, body and limbs, with feeling of heavi- ness; numbness and paralytic drawing in the extremities. Cr0talus.—-Nausea and vomiting, preceded or accompanied by faintness; extremely violent headache; burning, un- quenchable thirst; delirium, with staring eyes; anxious breath- ing; purplish spots on the skin‘; feeble pulse; pallid face; painful heaviness of the limbs. Argentum nit.——Cutting pains extending through the head from forehead to occiput, increasing and diminishing frequently; vertigo, photophobia, ringing in the ears, double vision; tongue coated white, or else black, hard and dry; sordes upon the teeth; lips and nails blue; breathing greatly oppressed; epileptiform convulsions; jerking and trembling of the limbs; face pale and emaciated; clouds before the eyes; deafness; in- continence of faeces and urine. C0cculus.—Headache, with vertigo, vomiting and feeling as if the eyes would be torn out; painful stiffness of the muscles of the neck; epileptiform convulsions; face pale and bloated; convulsive trembling of the head; miliary eruptions; fainting fits; constriction of the chest, with heavy and laborious breathing. Rhus tox.—Heavy, bruised feeling in the brain, extending to the ears and back of the neck; bruised feeling in the back and limbs; vesicular eruptions on the face and upper part of the body; vertigo, bleeding of the nose and somnolency ; dry cough, with perhaps bloody sputa; great restlessness, with intense aching in the limbs. C11prum.—Nausea and vomiting from cerebral congestion; nervous trembling, with hyperaesthesia of the senses; con- vulsions; sad, depressed features, with dim, sunken eyes, surrounded with blue rings; general paralysis; somnolency or coma. Belladonna.—Stupefying headache, worse in the back of the head and extending to the neck; pain in the neck ameliorated by bending the head backward; hyperaesthesia of the special senses; convulsive movements, especially of the muscles of the face and neck; grinding of the teeth; upper part of the 128 NERVOUS THERAPEUTICS. body hot, extremities cold; pupils dilated; delirium with or without coma; retention or inconstancy of urine. Plumbum.-—Early paralytic symptoms; limbs feel too heavy to be moved; heavy feeling in the back of the head; retraction of the abdomen; colic, with obstinate constipation; emaciation; somnolency. Lycopodium-—Headache, with pain extending down the neck; hyperaesthesia of the special senses; dyspnoea, with fanlilce movement of the nostrils; sense of constriction in the chest and - abdomen, as though bound with a hoop; numbness and twitching of the limbs; dreads solitude; melancholy and irritable. ]Ethusa cynap.-——During dentition, when accompanied by sudden, excessive, almost continuous vomiting, and attended by epileptiform convulsions; face pale, eyes staring, pupils dilated and insensible to light. I Arsenicum.—-Stiff, sore feeling in the back of the neck; scalp sensitive and painful; the characteristic thirst for but little Water frequently repeated; tetanic rigidity; spasmodic grind- ing of the teeth; great restlessness and prostration; vertigo; dulness of vision; anxious respiration; tongue dry and trem- bling; face pale and corpselike; diarrhoea; somnolency. Gantharides-Lancinating pains in the occiput, extending deep into the head; spasmodic constriction of the throat; priapism, with amorous frenzy; tetanic spasms; eyes staring; face pale, with terror-stricken expression; general coldness, faintness and trembling. Agaricus.——Drawing pains in the back of the head; stiffness and soreness of the nape of the neck and spine; violent pains all along the spine; delirium; somnolency. Zincum.-—Convalescence retarded; prostration of the vital power, with profuse and easy sweating; flushes of heat in head and face; trembling and twitching of the hands and feet; weak and watery eyes; weak memory; troubled with flatulent colic; priapism; dysuria; constipation. Auxiliary Treatment.—Local measures are usually of little avail. Ice to the head and spine sometimes has the effect of allaying the pain, but there is no evidence of its ever INFANTILE CONVULSIONS. 129 having done any permanent good. The same is true of heat, except so far as its moderate use during the collapsed state may help to restore the normal temperature. Stimulants, carefully administered, may also serve to help bridge over a dangerous crisis in the disease, but their use under any circum- stances in this disease is of very doubtful propriety. The diet during the earlier stage, or while the patient’s stomach is in a disturbed state, should consist chiefly of animal broths, which, if necessary, may be given by the rectum. At a later period more substantial food may be allowed, such as milk, eggs, oysters, fish and the like, care being taken that it be not only nutritious and easy of digestion, but acceptable to the patient’s stomach. INFANTILE GONVULSIONS. Synonyms.—'Infanti1e Fits or Spasms, Infantile Eclamp- sia, Eclampsia Infantum; Fr., Convulsions de l’Enfance; Ger, Kinderzuclcung, Kinderhrampf. -Definition.-—General clonic, epileptiform, acute spasms, occurring during infancy and childhood, and produced by transitory causes. Diagnosis-It is not always easy to distinguish infantile eolampsia from infantile epilepsy. The chief distinctions are embraced in the above definition. Eclampsia is an acute dis- ease, while epilepsy is chronic; the former depends on some permanent or hereditary influence, the latter on some acci- dental or transient form of irritation. Pathology.——Whi1e hereditary influences do not directly produce simple eolampsia, they no doubt strongly predispose to their occurrence. Nervous susceptibility is another impor- tant factor, and this is heightened by the absence of any vol- untary restraining influence emanating from the will. But the most potent factor is believed to be anaemia. In most cases this is both absolute and relative. The child’s brain contains more water than that of the adult. An anaemic con- dition is often induced by the operation of debilitating causes, such as impure air, insufficient or unwholesome diet, and other 18O NERvoUs THERAPEUTICS. devitalizing influences to which infants are far more often ignorantly or unintentionally than necessarily exposed. Therapeutic Indications.—Be1ladonna.-—Head hot and throbbing; face deep red or else pale; eyes injected, tremu- lous or staring; pupils dilated; intolerance of light; drowsi- ness, and starting from sleep as if frightened; great vascular excitement; mouth and tongue dry, with great thirst; pain in the neck; head drawn backward; great restlessness and tossing about; when aroused from stupor answers questions with a jerk; indicated in all cases where there is unmistak- able evidence of cerebral congestion. Gelsemium.—Pain, often severe, in the back of the head and neck; great nervous excitement, or else a stupid, comatose condition, from which the child is aroused with difficulty ; cere- bral hyperaemia during dentition; child constantly boring its head into the pillow; delirious as soon as it falls asleep; excess- ive irritability; eyes sensitive to light; cramps and spasms of the extremities; cries ‘out suddenly from time to time; especially indicated in cases produced by heat, or where there is marked cerebro-spinal congestion. Aconite.—Marked febrile excitement; hot, dry skin; child frets, cries out suddenly, gnaws its fists and starts as if fright- ened ; appears to be in great suffering; very restless; twitch- ing of single muscles; convulsions caused by fright, cold, teething and inflammatory affections, such as otitis, dysen- tery, etc. Ignatia.—-—Convulsions return periodically; child screams and trembles violently; kicks, jerks and has convulsive twitch- ings of single parts; convulsions extremely violent, with a predominance of tonic spasm; indicated after fright, during dentition, after being punished, or during the commencement of exanthematic fevers. Camphor brom.—Anaemic subjects, with pale lips, coldness of the body and extremities; after taking cold; when preceded or accompanied by a watery diarrhoea; when brought on by a suppressed catarrh ; when there is great physical prostration. Kali br0m.—Head hot and body and limbs cold; feet and hands blue and cold; eyeballs move in every direction; teeth- INFANTILE CONVULSIONS. 131 ing, accompanied by vomiting and diarrhoea; intestines con- tracted into a hard ball perceptible to the eye; great excite- ment of both the nervous and vascular systems; internal as well as external spasms; grinding of the teeth during sleep, with moans and cries; indicated where there is cerebral anaemia. Veratrum alb.--Anaemic subjects, in whom the convulsions are attended or accompanied by diarrhoea; face pale, with cold sweat on the forehead; child trembles all over; especially valuable when the child is very much prostrated after the spasm, or when secondary to pneumonia or cholera infantum. Cuprum.—The spasm begins in single muscles, or in the fin- gers and toes; is preceded by violent vomiting; is followed by loud cries; child lies on its face, or turns and twists vio- lently until the convulsion is repeated; bloated abdomen, with thin, watery, involuntary discharges; child fairly doub- lesitself up during the spasm; during dentition in anaemic cases. Cina.—Convulsive attacks at night or early in the morning; spasms of the extensor muscles, the child becoming suddenly stiff, followed by trembling of the whole body; unusual pallor about the nose and mouth, with flushing of the cheeks; child grinds its teeth during sleep; starts and moans during sleep; child is feeble and whines more or less when awake; very restless, throwing its arms wildly from side to side; is very feverish, and sometimes delirious, at night. 0pi11m.—After the spasm the child lies in a deep stupor; body trembles violently, while the limbs are convulsed; child screams before or immediately after the spasm ; indicated after fright of the child or of the nurse, or when there is much stupor, with retention of urine and faeces. Stram0nium.—-Heat of the head and body, with red face and staring eyes; spasms frequently repeated and continually changing their form; child is frightened by the approach of strangers and shrinks from them; abdomen swollen; urine profuse; when caused by the suppression of an eruption, or when the exanthem fails to make its expected appearance. Gl0n0in.——Skin hot, face flushed, head drawn back, spasms / 132 NERVOUS THERAPEUTICS. unilateral or bilateral; fainting spells, accompanied by difli- culty of breathing; bowels loose, with greenish, undigested stools; indicated in cases where there is marked cerebral con- gestion, attended by palpitations of the heart, dizziness, vomit- ing and oppression of breathing. _ Gypripedium.—Reflex convulsions, occurring in children of an excitable, nervous temperament, or where there is functional irritation of the brain, which renders the child sleepless even at night; child’s humor is very changeable, being playful at one moment and irritable and fretful at another; in cases of teething or of intestinal irritation. Hyoscyamus.—-Congestion of the head; face bloated and flushed; convulsive jerks of single muscles, or of a finger or hand; jerking and twitching of the facial muscles; grating of the teeth during sleep; eyes red and sparkling; child starts at every sound; shrieks from fright or fear; sickens after eating, and perhaps vomits; becomes insensible and froths at the mouth; spasms violent and last a long time. Zincum.-—Child starts and screams out in its sleep; has a startled look when it awakes; the whole body twitches and jerks; sometimes the convulsive movements are confined to one side or to single limbs or muscles; body hot; restless and irritable, especially at night; great appetite; bloated abdomen; anaemic children during the process of teething. Nux V0m.—-Spasms very easily renewed, and followed by deep sleep; when caused by indigestion, or by emotional excite- ment in the nurse. Stannum.—Irritative fever from worms, but with more excite- ment, more cerebral irritation and more fear than in Gina; convulsions from dentition or intestinal irritation. Oicuta.——Sudden and unexpected attacks of severe tonic con- tractions, affecting the whole body, and making it stiff and straight or bending it backward; clonic convulsions affecting the head and upper portion of the body; muscular spasms renewed by the least excitement of the child, or depending on verminous irritation. Cham0milla.—Extreme restlessness, child exceedingly cross and worrisome, can only be pacified by being carried about in POSTNATAL CONVULSIONS. 133 the nurse’s arms; disordered condition of the stomach and bowels; muscles of the face‘ and limbs twitch and jerk violently from intestinal irritation, or from nursing a woman who has just had a fit of anger and whose milk does not agree. Helleborus.—C/‘onvulsions of cerebral, or of apparently idio- pathic origin; intense pain in the head; urine dark, scanty and frequently emitted; convulsions followed by sudden re- laxation of the whole body, leaving the body cold and with a cold sweat on the forehead; tonic spasms of the cervical muscles. Ipecacuanha.—Great irritation of the stomach and bowels; frequent vomiting; convulsive attacks caused by indigestible food, or by a suppressed exanthem. Physostigma.—Convulsions caused by reflex irritation of the spinal nerves, especially when preceded by twitching and trembling of the muscles, dizziness and great weakness in the lower extremities; intestinal irritation produced by cold, worms, dentition, etc. Veratrum Vir.——Gonvulsions secondary to pneumonia, or when attended by fever, cough or diarrhoea; face pale, or bluish and cold, or covered with cold perspiration; violent vomiting, which is immediately renewed on taking the least food or drink; convulsive twitching of the muscles of the face and limbs, which are cold and da1np, or covered with a cold per- spiration. Auxiliary Treatment.—There is perhaps no disease in which accessory treatment is of greater importance, in most cases, than in infantile convulsions. This will be evident by a moment’s consideration of the fact that the causes are almost innumerable, and that unless the cause be removed a perma- nent cure cannot be expected. This suggestion may be all that is required under this head; if not, the reader will find the whole subject treated at length in the author’s Treatise on Diseases of the Nervous System, pp. 37-40. POSTNATAL CONVULSIONS. Syn0nymS.—Convulsions of the New-Born, Eclampsia 134 NERvoUs THERAPEUTICS. Neonatorum, Trismus Nascentium; Fr., Trisme de l’Enfance; Ger., Eklampsie der Neugeboren, Kinderstarrkrampf. Definition.—Spasmodic muscular contractions, of a tonic or clonic character, occurring shortly after birth. Diag'nosis.—The time of their occurrence, which is usually on or about the fifth day after birth (very rarely earlier than the second day, or later than the tenth), is sufficient to dis- tinguish them from ordinary infantile convulsions, with which alone they are liable to be confounded. Pathology.—Out of nine cases, Schuetz found haemorrhages six times in the intracranial cavity and twice in that of the spinal cord, while in only two instances did he observe inflam- mation and ulceration of the umbilicus, to which at one time they were supposed to be due. He therefore thinks that when by some unknown causes haemorrhages occur in either the cranial or spinal cavities, and produce sufficient pressure on certain nervous parts, “reflex manifestations and involuntary motions will follow, attacking larger or smaller complexes of muscles,” in other words, producing general or partial convul- sions. Clinical Experience.——This has been anything but flatter- ing. Cures, however, have been reported from the use of Hy- pericum, Passiflora, Arnica, Cicuta and Caloarea. Therapeutic Indications.-—These have already been given under the head of infantile convulsions, which see. Auxiliary Treatment.—As the disease very rarely occurs among infants that are kept dry and clean, in a pure atmos- phere and with comfortable surroundings, it is evident that hygienic measures are of primary importance, both in a pro- phylactic and therapeutic point of view. PUERPERAL CONVULSICNS. Synonyms.—Convulsions of Pregnancy and Parturition, Puerperal Eclampsia, Uraemic Convulsions, Eclampsia Gravi- darum et Parturientium; Fr., Convulsions des Femmes Enceintes et en Couche; Ger., Eklampsie in der Schwangerschaft und im Wochenbett. ' PUERPERAL coNvULsIoNs. 135 Definition.-—Convulsions occurring during pregnancy, dur- ing labor, and immediately at or soon after delivery. Diagn0sis.—This is obvious from the condition of the pa- tient and the history of the case. Pathology.—-Albuminuria exists in almost every case of puerperal convulsions; and as albumen and urea in the urine are in inverse proportion to each other, that is to say, when there is much albumen there is little urea, and when there is much urea there is little albumen, it is a generally accepted fact that most, if not all, cases of puerperal convulsions are due to _the poisoning of the blood with urea, either directly or by the carbonate of ammonia produced by its decomposition. Clinical Experience.-—The post hoc ergo propter hoe argu- ment has led to the acceptance of a very large number of rem- edies as specifics in this disease. Making proper allowance for this fact, the following list is entitled to confidence, provided, of course, the remedies are always given agreeably to their therapeutic indications: Cuprum, Hydrocyanic ac., Arsenicum, Hyoscyamus, Bryonia, Stramonium, Digitalis, Pilocarpus, Ascle- pias syr., Veratrum vir., Gelsemium, Belladonna, Opium, Lachesis, Ignatia and (Enanthe croc. The following remedies will pre- vent, it is said, the full development of threatened convul- sions if given in time: Apis, Helonias, Apocynum can., Eupato- rium purp., Kalmia and Barosma. Therapeutic Indications.-— C11prum.—Convulsions alter- nate with delirium and nervous dyspnoea; are followed by blindness or deafness, or by apathy and great indifference; during the paroxysm the face is red and distorted, eyes pro- truding and staring, tongue and breath cold; spasms chiefly affect the extensor muscles; patient frequently screams out, as if in great anguish. Hydrocyanic ac.——Convulsions occurring suddenly, and at- tended by great depression, slow, moaning breathing and in- sensibility; spasms, partial or general, with great distortion of the features and limbs, or with the trunk bent forward; spasm of the larynx, with symptoms of suffocation; inability to swal- low; rattling in the trachea; extreme anguish; action of the heart greatly diminished; extreme prostration. I 136 NERVOUS THERAPEUTICS. Arsenicum.—Tonic and clonic spasms, with great distortion of features, limbs stifl’ and hands clenched; after the parox- ysm the patient exhibits great exhaustion ; sudden sinking of strength, with faintness; lies in a stupor like one dead, breathing imperceptibly. Hyoscyamus.-—Clonic convulsions, either partial or general, violent, accompanied by shrieks and great oppression of the chest; face pale, with cold perspiration, or bluish-purple and bloated; unconscious and delirious; extensor muscles violently convulsed. Bry0nia.——Convulsive jerking of the extremities, beginning in the fingers and toes and extending to the whole limb; cramps in the knees and calves of the legs; worse in the morn- ing and after eating; drawing sensation along the spine, fol- lowed by violent contraction of the extensor muscles, bending the body backward like a hoop; face red and bloated; very apprehensive as to reco.very. Stram0nium.—Patient very excitable, hysterical, delirious, and has frightful or agreeable visions, with corresponding moods and actions, laughing, singing, attempting to escape, etc.; con- vulsive movements of every muscle, distorting the face, body and limbs; convulsions easily excited and frequently renewed. Digitalis.-—Frequent convulsions, with drowsiness and insen- sibility; heart greatly embarrassed, weak and palpitating, and frequently intermits. ‘ Pilocarpus pennat.—Puerperal convulsions, attended with high arterial excitement, hard pulse, heavy blood pressure; perspi- ration, with free flow of saliva; dyspnoea, threatening suffo- cation. Asclepias syI'.—Uraemic convulsions, preceded by severe headache, with sharp pains through the temples, or with a sense of constriction across the forehead, full, quick pulse, and nausea or vomiting; attacks preceded by profuse, then scanty or suppressed urine. Veratrum vir.—Oonvulsions attended by high arterial excite- ment, violent delirium, flushed face, thirst, hot and sensitive skin, followed by a weak, scarcely perceptible pulse, and cold, clammy skin, dilated pupils and oppressed breathing. PUERPERAL CONVULSIONS. 137 Gelsemium.—Passive congestion of the head and face, stupid look, thick speech, slow, full pulse; labor protracted by rigid os uteri; apoplectiform convulsions during labor. Bel1adonna.—Active or passive cerebral congestion; face red or livid, pupils dilated, speech thick or lost; convulsions par- tial or general, frequently repeated and attended by loud cries, contortions of the face and delirious mutterings; parox- ysms followed by quiet, unconscious sleep, or by disturbing spasmodic movements and visions. Opium.-—Uraemic coma following puerperal convulsions; con- vulsive rigidity of the body; red, bloated face and stertorous breathing; retention of stool and urine; low, incoherent mut- tering; apoplectiform convulsions during or after labor. Lachesis.——Convulsions continue longer and are more severe about the throat than elsewhere; complains of pains without being able to locate them ; redness of the face, violent convul- sions of the facial muscles and jerking of the extremities, most violent on the left side; trembling of the body and limbs be- tween the paroxysms. Ignatia.—Great nervous excitement, manifesting itself in cries, sobs and paroxysms of laughing; loquacious and then taciturn; tries to kick the cover off the bed; constantly pull- ing at her hair; urine turbid and scanty; suffocative fits of breathing; panting between the spasms, which are often lim- ited to the muscles of the upper part of the body, the neck and the face. (Enanthe croc.——Epileptiform convulsions, with swollen and livid face, followed by coma or deep sleep, or else with syncope, insensibility and deathlike coldness; apoplectiform convul- sions, with convulsive respirations, dilated pupils, insensibility, feeble pulse and great prostration ; wildly delirious; tetanic contraction of the limbs. Auxiliary Treatment.—As a general rule the sooner the womb is emptied of its contents the better, as this alone often suflices to put an end to the convulsions. When, therefore, the spasms occur during labor, artificial delivery should be speedily effected, unless there is some weighty reason for deferring the operation. The same is often true when the con- 10 138 NERvoUs THERAPEUTICS. vulsions set in previous to labor, provided they seriously threaten a miscarriage. Even when they occur subsequent to parturition it is important to remove any clot, membrane or portion of the placenta which may have been retained, as the convulsions seldom, if ever, entirely cease so long as any of the contents of the womb remain in the uterine cavity. TOXJEMIC CONVULSIONS. Syn0nyms.—Convulsions from Poisoning of the Blood, Uraemic Convulsions, Cholaemic Convulsions, Convulsions from Inanition, Eclampsia Toxica; Fr., Convulsions Toxémiques; Ger, Eklampsie-blutvergiftung, T oxdmische Eklampsie. Definiti0n.—Convulsions resulting from the introduction or retention of poisonous substances in the blood. Diagnosis:-As in other forms of eclampsia, the history of the case, together with the appearance of the patient, is usually sufficient to establish the diagnosis. Thus, uraemic convul- sions occur either in connection with parturition or disease of the kidneys; cholaemic convulsions result from the introduc- tion of decomposing products of animal secretions into the blood; and the convulsions of inanition are induced by the intoxicating effect of the deteriorated blood upon the nervous centres. Pathology.—The pathology of uraemic convulsions occur- ing in connection with parturition is given in the previous section, which see. They likewise occur in the course of scar- latina in consequence of sudden obstruction of the urinary passages with croupous exudation. They may also be pro- duced by any affection of the kidney, such ‘as Bright’s disease, which interferes with the secretion of urine, or by a re-absorp- tion of urine which has been previously effused into the cellu- lar tissue, especially after the urine is decomposed and the blood becomes surcharged with the carbonate of ammonia (ammoniaemia). Cholaemic convulsions occur most frequently in acute atrophy of the liver, as on account of the destruction of the hepatic cells the function of the liver then ceases. In short, whenever from any cause the blood becomes so impure EPILEPSY. 139 as to irritate the convulsive centre in the medulla oblongata, toxaemic convulsions are the result. Clinical Experience.——A1l worth mentioning will be found under the heads of cerebral hyperaemia, cerebral anamia and puer- peral convulsions, which see. Therapeutic Indications:-See previous sections, especi- ally those pertaining to convulsions. Auxiliary Treatment.—Hygienic measures, especially such as will tend to 'purify the blood, are of the highest im- portance. Hence pure air, water, and a blood-making diet of beef and other animal food, are required in all cases. Mas- sage is also of great benefit by its renewing effect upon the tissues. EPILEPSY. Synonyms.—-The Falling Sickness, Morbus Magnus, M. Major, M. Daemonius, M. Divinus, M. Deificus, M. Lunaticus, etc., Epilepsia, Epilepsis; Fr., Philepsie, Mal Divin, Haut Mal; Gen, Fallsucht. Definition.-—A chronic, non-febrile, nervous affection, char- acterized by paroxysms of loss of consciousness and, with very rare exceptions, by tonic and clonic convulsions. Diagnosis.—Is there any way of positively diagnosing an epileptic paroxysm, as such, without reference to its history‘? No! Eclamptic and epileptic convulsions accompanied by loss of consciousness belong to the same group of symptoms; the only difference is they occur under different conditions. The one is acute or transitory, the other chronic, and recurs in conformity to an established epileptic habit. No doubt there is such a thing as infantile epilepsy, but such cases are indeed very rare. Up to about the third year of life the epileptic habit is not likely to become established, while after that period local irritations, either internal or external, are not likely to cause convulsions without the pre-existence of an- inherited morbid state of the nervous centres. Epilepsy is liable to be mistaken for hysteria, which is not only chronic, but often simulates epilepsy very closely. In epilepsy the loss of consciousness is sudden and genuine; 140 NERVOUS THERAPEUTICS. there is no recollection of the attack afterward; the eye is fixed, the features often distorted and the tongue bitten. In hysteria, on the other hand, the attack is not sudden, con- sciousness is not entirely lost, and there is no reckless injury of the tongue or person. Syphilitic epilepsy may be distinguished from idiopathic epilepsy by the fact that it occurs in those who have not had epilepsy in early life and who have reached the age of at least thirty years; the disease is frequently associated with or is followed by some form of paralysis, generally partial; the attacks are frequently preceded by headache, likewise partial, and the convulsions occur often, that is, many in quick suc- cession, the interval between the series of attacks being com- paratively long; the periods of quietude, however, are not free from headache or other nervous symptoms which exist and often become aggravated——-conditions contrary to what usually obtain in simple or idiopathic epilepsy. Pathology.-—Although no constant anatomical changes have yet been observed in this disease in any of the great nerve centres, the fact that it is in most cases an hereditary affection, and chronic in its nature, renders it almost certain that it is something more than a mere functional disorder, and this accords with the latest investigations, which go to show that it depends, in a measure at least, on certain histo- logical changes in the medulla oblongata. Cortical epilepsy is only a peculiar form of peripheral epilepsy, the cortical irritation being reflected upon the convulsive centre or cen- tres in the medulla, as in other cases of reflex epilepsy. Clinical Experience.-—Notwithstanding the universally admited fact that genuine epilepsy is extremely difficult of cure, the number of remedies to which such cures have been assigned are almost too numerous to mention. I shall there- fore refer here to only a few of those whose recorded cases are before me. Indigo is said to have cured a case where the men- tal symptoms were those of melancholy. Dr. Quezada says that when he was a boy, aged 13, he had fourteen epileptic attacks, and that he was permanently cured by the fruit of Capparis cor., or “simulo,” a plant indigenous in Peru. Dr. EPILEPSY. 141 Foster prescribed Cannabis ind. in a case of forty years’ stand- ing—i11 which an unfailing premonition of an approaching attack was a feeling of extraordinary mental and physical vigor—-in doses of one-tenth of a drop every hour when she felt thus “exalted,” with the result that she has had but one slight seizure since she began the use of it, now nearly three years, while before she had about thirty annually. Glonoin, 2x dil., is said to have cured many cases. Calcarea ars., rec- ommended by Dr. Hering, is said to have benefited several, and entirely stopped a few cases. Dr. Buller claims to have cured epilepsy with Cotyledon umb. Belladonna is credited with a large number of cures, but as most of them occurred in children, I am inclined to regard most of them as cases of ordinary infantile convulsions. Coceulus, according to Hughes, has made several undoubted cures. Ouprum acet., 3x, cured a case where every usual remedy had failed, fifteen years having since elapsed without any return. Nux vom., 3x, cured a case of sixteen years’ standing; four years have passed without any return. Hydrocyanic ac., 3x, has cured, according to Dr. Hughes, several cases of recent date. Argentum nit., 1x, 2x, has effected several permanent cures. Thaspium, 3x, has, it is said, cured two genuine cases. Glnanthe croo. is also credited with a cure. Therapeutic Indications.—Indigo.--Exceedingly depressed and melancholy; great languor and weariness; unusual feeling of prostration, especially in the lower limbs; convulsions pre- ceded by a fit of the blues; the aura seems to come from the abdominal ganglia; sometimes the attack begins with dizzi- ness. (lapparis cor.-—Fit occurs suddenly, almost without warning; convulsions terrific, tonic and clonic, general, with foaming at the mouth, usually reddened with blood from a bitten tongue; very stupid for a long time after the fit has passed off. Cannabis ind.-—Fit immediately preceded by a feeling of ex- traordinary mental and physical vigor; mind and body in a state of ecstatic evaltation; on regaining consciousness violent shocks pass through the brain; some cases are preceded by active cerebral congestion, throbbing, ringing and buzzing in the ears, sensitive to light and noise. 142 NERvoUs THERAPEUTICS. Glonoin.-—Attacks immediately preceded by flushed face, headache, ringing in the ears and other evidences of cerebral hyperaemia; increased action of the heart and arteries; nausea and vomiting, dizziness and oppression of breathing; convul- sions tend to become more and more frequent. Belladonna.—Recent cases, with decided brain symptoms; previous to the attack, headache, throbbing in the temples, dilated pupils, intolerance of light, redness of the face; after the attack, anxiety, fear of imaginary things, disturbed sleep, vertigo, peevishness, flushed face, startings during sleep; con- vulsions commence in the upper extremities; clutching of the throat during the fit. Cocculus.—-Debilitated, nervous subjects; circulation sluggish, a sort of passive congestion, veins standing out like whip-cords ; vertigo, with nausea; great lassitude, making it diflicult to stand firmly; convulsions begin in the fingers and toes. Cuprum.—Convulsions follow each other in rapid succession, the convulsive state rather remitting than completely inter- mitting; aura emanates from the region of the stomach; patient very restless after the attack, with headache, soreness of the flesh and prostration; convulsions begin in the extremi- ties; hands and feet cold, face livid or pale; involuntary dis- charge of urine; hysterical mood. Nux vom.—Stomach weak and disordered, tender to the touch; pressure over the stomach renews the attack; convul- sive twitching in the limbs and trembling of the whole body; spinal epilepsy. Hydrocyanic ac.-—Recent cases, attended by sudden and com- plete loss of consciousness a11d sensation; body blue and cold; fit quickly merges into a comatose condition, interrupted only by a renewal of the convulsive movements, which usually begin in the extremities and afterward become general; great drowsiness and prostration after the fit. Argentum nit.—Pupils dilated a day or two before the attack; aura rises slowly from the region of the stomach, which feels oppressed as by a load resting upon it; head feels dull and stupid; mind exceedingly depressed and melancholy; convul- sions sometimes preceded by active cerebral congestion. EPILEPSY. 143 Thaspium aur.——-Flushed cheeks, hot head, visible pulsations of the carotid and temporal arteries; great exhilaration or great mental depression; hysterical mood; headache, with nausea, precedes the attack. Qlnanthe croc.-Convulsions attended with vertigo, nausea, vomiting, unconsciousness, coma or deep sleep ; convulsions, with deathlike syncope, coldness as if dead; tetanic contrac- tion of the muscles of the jaws and limbs; convulsions epilepti- form in all cases, pupils dilated, eyeballs turned up, frothing at the mouth, face swollen and livid; madness with the convulsions. Chininum ars.—Attack followed by cold perspiration, eructa- tions and a sense of utter prostration. Plumbum.-—Convulsions preceded by numbness of the legs; swollen tongue; consciousness returns slowly and imperfectly; chronic cases. Silicea.—-Attack preceded by shaking of the left arm and great coldness of the left side of the body; slumber, with start- ing; spasms seem to undulate from the solar plexus toward the brain; violent screaming, groaning and foaming at the mouth, followed by warm perspiration, slumber and paralysis of the right side. Auxiliary Treatment.—A large proportion of these cases belong to the reflex variety, and depend upon causes which can be removed during the interval between the attacks. One case of fifteen years’ standing was accidentally cured in treating the piles. Another was caused by the larvae of flies in the in- testines, the removal of which speedily cured the patient. Many cases depend on some disturbance or irregularity of the menstrual function, which requires to be corrected. But the most numerous of those occurring among young persons, of both sexes, are the result of self-abuse, and require not only great care and surveillance on the part of parents and guar- dians, but moral treatment as well. The fathers of medicine very properly laid great stress upon the importance of a suitable diet in epilepsy. Celsus and Aretoeus advise “a soft diet free from crudities.” Boerhaave says that “great frugality in diet cures epilepsy.” Echeverria says that “diet and exercise are of more value than medicine.” 144. NERVOUS THERAPEUTICS. Experience shows, however, that there is no specific diet suit- able for all cases of epilepsy. Some recommend a meat, others . a milk, farinaceous or vegetable diet; but the experiments of Merson, Gowers and others show that, applied indiscriminately, neither of these kinds is curative. At the same time there is no doubt that purely vegetable food and a milk diet has pro- duced many a lasting amelioration. My own opinion, how- ever, is that this sort of diet is best suited to full-blooded, plethoric patients, while meat diet is best adapted to weakly, anaemic ones. Nocturnal cases are also, as a rule, benefited by a stimulating meat diet, while those occurring during the daytime require an unstimulating, milk or vegetable diet. Excesses in eating and drinking should never be allowed; and as for alcoholic drinks, smoking, and even coffee and tea, they had best be entirely prohibited. TETANUS. Synonyms. ——Spasm with Rigidity, Lock-jaw, Central Myelitis, Entasia Tetanos, Trismus; Fr., Tétanos; Gen, Starrlerampf. Definition.—A disease characterized by a rigid contraction of the voluntary muscles, alternating with a greater or less degree of relaxation, caused by an irritated or overexcited state of the medulla oblongata and spinal cord. Diagn0sis.—Tetanus is not likely to be mistaken for any other natural disease, unless it be hysteria, which sometimes bears a slight resemblance to it. The history, duration and characteristic symptoms of the two diseases are, however, amply sufficient to distinguish them from each other. Not so, however, with toxic tetanus, especially that form of it pro- duced by strychnia ; and as the latter is frequently employed for purposes of murder and suicide, it is important to be able to discriminate between the natural and the artificial disease. In the former the spasm first takes the form of trismus or lock-jaw, while in the latter the lower extremities are first involved; the hands also are generally affected in these cases, while in the natural disease the upper extremities TETANUS. 145 usually escape altogether. Not only so, but the duration of tetanus is usually much greater than that of the tetanoid affection produced by strychnia, which generally proves fatal within less than an hour of its commencement. Path0l0g‘y.—Various lesions of the spinal cord have been discovered after death from tetanus, the most important of which consist in an enlargement of the bloodvessels, together with granular disintegration of the nerve-tissue; but as many cases occur in which no pathological changes can be detected, at least nothing sufficient to account for the convulsions, it is by no means certain that these alterations are the causes, or only the effects, of the tetanic manifestations. Indeed, there are circumstances which seem to indicate that the spinal cord is not the primary centre of reflex action in these cases, but that the morbid influence, whatever it may be, that causes the disease, is first transmitted to the medulla oblongata, and afterward extends to the cord. Clinical Experience.-—The following remedies have been used successfully in tetanus in a number of instances: Bella- donna, Atropine, Narcotin, Cicuta, Passiflora, Gelsemium, Physos- tigma, Stramonium, Lachesis, Hydrocyanic ac., Angus. vera, Ver- atrum vir., Arniea and Hypericum. Among the homoeopathic remedies which have greatly ameliorated cases of tetanus are: Aconite, Hyoscyamus, Phytolacca, Kali brom., Bryonia, Ouprum, Arsenicum, Nux vom., Ignatia, Cannabis ind. and Curare. Therapeutic Indications. — Belladonna. — Cerebro-spinal congestion; stiffness of the jaws, with convulsive movements, dilated pupils, diflicult deglutition, staring eyes, restlessness, spasmodic respiration, involuntary discharges of urine; sudden jerks and shrieks during sleep; opisthotonos; pleurosthotonos, especially to the left side. Nicotinum.-—Icy coldness of the limbs; violent tetanic spasms, succeeded by relaccation and trembling; extreme palor, nausea and prostration; coldness and shuddering of the whole body; dry, hot skin, with thirst and quick pulse, succeeded by cold skin, weak, thready pulse and labored, irregular breathing. Cicuta ViI'. —Trismus; legs and arms flexed and rigid; abdomen distended and hard; spasms every half hour; edges 146 NERvoUs THERAPEUTICS. of the tongue covered with white ulcers; spasms of the oesophagus; spasms of a tonic character; paleness of the face during the spasm. Passiflora incar.— Violent tetanus, with opisthotonos, trismus and convulsions in a child two years old ; ‘produces, it is said, prompt, perfect and permanent cures in both men and horses, also in trismus nascentium. Gelsemium.—Traumatic tetanus; stiffness of the jaws, with pain and stiffness in the back of the neck; spasmodic feeling in the pharynx and oesophagus, with difficulty of swallowing; con- strictive feeling in the chest, with great difficulty of breathing; pupils dilated; cramps in the legs; convulsive action of the voluntary muscles; involuntary discharges of faeces and urine; abdominal muscles rigid; darting pains in the wounded leg, which jerks and twitches whenever it is touched; hard, feverish pulse; breathing irregular and hissing. Physostigma.—Twitching and trembling of the muscles; trembling, convulsive action of the respiratory muscles; tendency to fainting; alternate dilatation and contraction of the pupils, the former corresponding with the period of the spasm, and the latter with that of quiescence; opisthotonos; no control over his urine, which is passed invohintarily. Stramonium.—Traumatic tetanus; opisthotonos; apoplectic condition, with snoring, red face and deep sleep; body hot; urine copious; grinding of the teeth; contortion of the hands; shuddering; spasmodic constriction of the oesophagus; con- striction of the chest, with difficult breathing; forehead cold; pulse scarcely perceptible; lower limbs drawn up with great force, then straightened out and so rigid that they could not be bent; eyes tightly closed, with occasional twitching; wounded hand swollen and erysipelatous. Lachesis.——-Tetanic look, with half-closed eyes and stiffness of the neck; trismus; opisthotonos; rigors; shooting pains in the back; throat sensitive to contact and swallowing almost impossible; two cases cured. Hydrocyanic ac.—Tetanic spasms, with trismus, protruded and glistening eyes, bloated face and neck; passive cerebral congestion. TETANUS. 147 Angustnra vera-—Violent tetanic paroxysms, with opistho- tonos; twitching and jerking along the back, like electric shocks; tetanic spasms excited by the least touch, noise or the drink- ing of tepid water; thirst, without any desire to drink; pulse intermittent but rapid. _ Veratrum vir.——Tetanus depending on pneumonia; opistho- tonos; no relaxation of the muscles of the back for five days; heels almost touched the head like a hoop; body covered with a cold, clammy sweat; remedy not prescribed until after the febrile reaction had set in. Arnica.—Traumatic tetanus; internal chilliness with ex- ternal heat; pulse variable, mostly hard, full and quick; muscles and limbs twitch and jerk; weary, bruised feeling, making everything feel too hard; breathing short and panting; face hot, body cold; jerks and electric-like shocks; tremor of the limbs. Hypericum.-—Traumatic tetanus, 'with trismus and opistho- tonos; swallowing difficult; hardness of the cervical muscles; face distorted; nostrils dilated; no relapse. Auxiliary Treatment.-—Warm baths; sweating, produced by passing hot air inside a covered framework adjusted to the bed by means of a tube connected with a heated cylinder; flannel cloths wrung out of hot water, of a temperature just bearable to the hand, and applied to the nape of the neck and along the spine; ice, and the spinal ice-bag; and the division or stretching of any nerve-trunk connecting the wound with the spinal cord, have all been resorted to with more or less benefit in different cases. In order to support the patient during the severe illness through which he is passing, he should be made to swallow, if possible, an egg, or half an ounce of raw meat juice, mixed with three or four ounces of milk, every four or five hours during the day. If great exhaustion ensues, or the patient is unable to swallow, peptones, or beef-tea and brandy, should be given per annum. 148 NERVOUS THERAPEUTICS. HYDROPHOBIA. Syn0nyms.—Dog Madness, Canine Madness, Lyssa, Rabies; Fr., La Rage, Hydrophobic; Ger, Hundswuth, Tollwuth, Wasser- scheu. Definiti0n.—An acute spasmodic disease, allied to tetanus, produced by the inoculation of a specific animal poison, usually through wounds made by animals suffering with rabies, the symptoms indicating great disturbance of the central nervous system. Diagn0Sis.—The diseases most liable to be mistaken for hydrophobia are tetanus, spurious hydrophobia and acute mania. In tetanus the result usually follows the injury within a week or ten days; in hydrophobia it seldom occurs short of two or three weeks, and is often delayed many months. In tetanus, again, the convulsions are continuous, and are usually combined with trismus ; moreover, there is no mental distur- bance, no increase in the secretion of saliva, and no well- marked respiratory spasm, as we find in hydrophobia. Spurious hydrophobia, from the great resemblance of its symptoms to those of the genuine disease, is more diflicult of detection. Such cases, however, usually occur in the hysteric constitution, present a less serious aspect, are free from any mental derangement except what arises from fear or anxiety, and are more easily subdued by treatment. From acute mania the affection may be distinguished by the history of the case, the rapid course of the disease, and the persistency with which the convulsive paroxysms, which are never absent, return. Path0l0gy.—The morbid appearances in the medulla ob- longata and spinal cord, as described by Allbutt, Benedek, Coates, Gowers and others, consist mainly of changes in the nerve-cells and vessels——the pressure of round cells; leucocytes in the perivascular spaces, in the nerve-tissue itself, and among the nerve-elements; granular degeneration, and even embo- lism; the changes being most marked about the respiratory centres in the medulla. None of these lesions, however, are characteristic; they throw little light on the essential nature of the disease, as similar changes are observed in other affec- HYDROPHOBIA. 149 tions. Gower’s opinion, which is substantially that of other pathologists, is, “that the vascular changes, from their vari- ability and occasional absence, are probably secondary effects of the disturbed action of the nerve-centres produced by the poison carried by the blood.” Clinical Experience.—'1‘he most interesting, and, in some respects, perhaps the most important clinical experience in this disease, is that of M. Pasteur on the protective power of inoculation. The results, for which alone we have roo1n, are so far, I am sorry to say, very unsatisfactory. They may be summed up as follows: (1) Animals which have been inoculated hypodermically by M. von Frich, after Pasteur’s method, have not been protected from infection with the fresh virus of street rabies, and have only exceptionally escaped after intracranial infection, although inoculated during ten days with virus of progressive virulence (medulla from ten days to one day). This result is diametrically opposed to that claimed by Pasteur himself, who asserts that animals so treated are proof against any ordinary inoculation. (2) M. Pasteur, having attributed the unsatisfactory results obtained by M. von Frich to too slow vaccinations, recommended a more intensive mode of treat- ment, whereupon M. von Frich instituted a fresh series of experiments, which he carried out conformably to M. Pasteur’s instructions, but with no more favorable result; all the ani- mals died of rabies. (3) Most of the animals which were sub- mitted to the preventive treatment after subcutaneous inocula- tion with street rabies died of the disease, even when the period of incubation was thirty-four days. These experiments show, as claimed by M. von Frich, that Pasteur’s method of rendering animals refractory to rabies is not yet either sure or certain. There is not yet a suflicient scientific basis for the application in man of a preventive treatment after the bite of a rabid animal. It is, moreover, quite possible that the pre- ventive treatment, at any rate the intensive method recently recommended by M. Pasteur, may itself transmit the disease. As for the curative power of medicine in hydrophobia, we can only say that a “prodigious” number of remedies lay claim to it, as the following list will show: Xanthium spin.—This remedy has been declared by Dr. 150 NERvoUs THERAPEUTICS. Grzyvala, of Podolia—-for whose truthfulness Prof. Gubler, of Paris, vouches—a specific for hydrophobia. He says that dur- ing the Crimean war a family of twelve persons had been bitten by a hydrophobic wolf; six of them entered his wards at Olschanka, Podolia; they were treated with an infusion of the leaves of this remedy, and all recovered; the other six, who were treated by the actual cautery and the daily use of Genista tinctoria and’ other drugs, died in the course of from twelve to sixty days. He recounts many other cases, and says that out of at least one hundred cases he has not failed to save every one. Out of a herd of thirty oxen bitten by a mad wolf, eight succumbed to hydrophobia; the commissary of police obtained the “anti-rabic” powder of Dr. Gr. and gave three ounces daily to each of the others, saving every one of them. Hoang-Nan.—M. Perrier, missionary at Tonquin for twenty years, declares that he has cured a young girl of 14 of hydro- phobia with this remedy; she afterward grew up, married, and is now a mother. Spirma nlmar.——Kuhner, of Russia, says that during a frantic paroxysm of hydrophobia a patient devoured a piece of the root of this plant; fifteen minutes afterward he became con- scious, vomited, and fell into a profound sleep of twenty-four hours, and was well afterward. Inula helen.—Dr. Helmuth cites the following cure by this remedy: In 1858 a policeman, so far gone with hydrophobia as to have to be held in the carriage in which he was being driven to Germantown to the residence of Mr. Frye, was treated exclusively with Inula helenium with success. Tanacetum vulg.-—M. Hayem, in the name of M. Peyraud, of Libourne, has shown the resemblance which exists between true rabies and what he calls tanacetic rabies, that is to say, rabies caused by the essence of tansy. “If rabbits,” says M. Peyraud, “ on whom one has previously practiced the injections of tansy for a period of six, seven or eight days, he submitted to the action of rabic virus, it will prevent these animals from developing rabies. All of those to which I have given this preventive treatment, during the past eight months, have not been attacked by rabies, while two rabbits which I had inocu- lated with rabic virus without having previously submitted HYDROPHOBIA. 151 them to the preventive tanacetic injections, have both of them succumbed to the true rabies, one very rapidly, the other more slowly.” This is true homoeopathy, and therefore a great im- provement 011 Pasteur’s method, even if all that is claimed for the latter is true, which is very far from being the case. The following remedies have also been favorably reported upon in this disease: Scutellaria (Vanderveer), Belladonna (Adams), Euphorbia (Ruddock), Lachesis (Toothaker), Stramon- ium (Morgan), Hydrophobin (Berridge), Tabacum (Norton), Cannabis ind. (Ruxton), Mercurius corr. (De Capua), Gelsemium (Dubbs), Simaruba Cedron (V allant), Genista lutea (Fox), Can- tharis (Hartlaub), Hyoscyamus (Hahnemann). Therapeutic Indicati0ns.—These will be found in previous sections, especially under the heads of cerebral and spinal hyperxmia, convulsions and tetanus, which see. Auxiliary Treatment.—Prophylaxis.—-Immediately after a person is bitten by a rabid animal the wounded part should be forcibly sucked, or, if favorably situated for the purpose, a cupping glass may be applied ;_ then, instead of excising the wound, which endangers the infection of the freshly cut sur- face by virus from the blade of the instrument, the pure nitrate or chloride of silver, or other caustic, should be applied to every recess of the wounded part, so as to decompose the virus and destroy the vitality of the affected tissues. This plan is rec- ommended by Youatt, who was himself bitten several hun- dred times by rabid dogs without becoming infected after applying the caustic in this manner. He prefers the chloride of silver for the purpose, as being a more efficient caustic than the nitrate. If the patient can be induced to submit to it, and the case is a very suspicious one, it is safer to use the actual cautery, in the form of a white-hot iron. A poultice should then be applied until sloughing of the eschar occurs, after which, if deemed advisable, the wound may be kept discharg- ing, by any simple stimulating ointment, until the.period of greatest danger is passed, or until it fills up with healthy granulations. Among other accessory measures which at different times have proved of greater or less benefit in these cases, the most 152 NERVOUS THERAPEUTICS. efficient are the steam bath, ice to the spine, Faradization and galvanism. osomia. Synonyms.-—St. Vitus’s Dance, St. Guy’s Dance, St. J ohn’s Dance, Chorea Sancti Viti, Chorea Minor; Fr., La Chorée, Folie Musculaire, Danse de St. Guy, Danse de St. Witt; Ger, Veitstanz. Definiti0n.—An affection of the nervous system, character- ized by a succession of uncoordinated movements of the volun- tary muscles, occurring almost exclusively in the waking state, in almost all parts of the body, and either entirely withdrawn from the sphere of volition, or but little under its control. Diagnosis:-Partial choreic movements, or local choreas, are apt to be mistaken for true chorea; they differ from the latter not only by being definite spasms located in one part—— as, for example, twitchings on one side of the head or face- but in being usually incurable. Chorea bears some resem- blance to tremor, and especially to that form of it called pa- ralysis agitans, but these disordered movements are usually confined to adults and the aged, besides being more rhythmical and restricted. Chorea differs from hysteria by its proneness to attack children, and by the movements being little if any under the control of the will, while hysteria is mostly a disease of adult life, and is ameliorated rather than aggravated by voluntary exertion. Chorea magna is an entirely different affection from chorea minor, or what is commonly called chorea, consisting as it does of a series of complicated move- ments occurring at irregular intervals, and exactly simulating voluntary movements—such, for example, as taking three steps forward and then making a low bow, or rising from a chair, jumping over it, and then sitting down again as if nothing had happened—actions which result from an entirely uncontrollable impulse. These forms of so-called chorea have at times prevailed as regular epidemics (tarantismus), and par- take more of the hysterical nature than they do of true chorea. Path0l0gy.—The fact that ninety-nine out of a hundred cases of chorea minor are curable, renders it almost certain CHOREA. 153 that no serious lesion, such as minute emboli, softening, etc., exists in either of the great nerve-centres. It is true that in a few fatal cases post-mortem examination has revealed such changes, but these are the exception rather than the rule. Besides, fright is one of the most common causes of the disease, and surely fright is not capable of producing serious organic disease. I am therefore disposed to regard the choreas of childhood as functional neuroses, often associated with the rheumatic diathesis, or with cardiac disease depending upon it, together with an enfeebled state of the nervous system, the result of anaemia impairing the nutrition of the nerve-centres. Clinical Experience.—The remedies which have received the strongest indorsement of the profession in this disease are: Mygale las., Agaricus mus., Oimicifuga, Causticum, Pulsatilla, Coc- eulus, Nux vom., Ignatia, Hyoscyamus, Tarantula, Calcarea, Gup- rum, Zincum, Stramonium, Asterias rub., Sulphur, Veratrum vir. and Cina. Therapeutic Indications.—Myga1e.-Muscles of the face jerk and twitch; eyelids and mouth open and close in rapid succession; in trying to put the hand to the mouth it is arrested midway and jerked down; gait unsteady; legs in motion while sitting, and dragged while attempting to walk; constant motion of the whole body; indicated in all typical cases 11ot especially calling for some other remedy. Agaricus.——Marked and frequent nictitation or twitching of the eyelids; spasmodic movements, from simple involuntary motions and jerks of single muscles to a dancing of the whole body; trembling of the limbs; soreness of the spine; redness of the eyes; involuntary movements cease while asleep; symp- toms worse during a thunderstorm. Cimicifuga.—Mind greatly depressed; great nervousness; muscular twitchings resembling chorea, the left side being most affected; pain under the left breast; tenderness over the last cervical vertebra; tenderness over the ovarian regions; especially suited to cases occurring in young girls at or about the age of puberty, or when there are present symptoms indic- ative of menstrual disorder. Causticum.—Ghoreic movements even in the night; move- 11 154 NERvoUs THERAPEUTICS. ments involve the right side of the body more than they do the left; the muscles of the tongue are affected so that the speech is thick, and the words have to be jerked out; there is a marked paretic condition of the affected parts; especially indicated in rheumatic cases, or when resulting from cold or exposure. Pulsatilla.——Symptoms due to disease of the genital organs, such as amenorrhoea, dysmenorrhoea, ovaralgia, etc.; choreic movements occurring in young girls at or near puberty. Cocculus.——Movements chiefly confined to the right side of the body, as the right arm or the right leg; menses dark and scanty; thin, scrawny girls, with irregular periods, and subject to venous or haemorrhoidal congestions; tendency to paralysis of the affected parts. Nux v0m.—Numbness of the affected parts, also formication; impaired appetite; constipation; vague flying pains about the chest and legs; movements renewed by the least touch, but diminished by strong and steady pressure; symptoms worse early in the morning; chronic cases, especially such as have been under old-school treatment. Ignatia.-—Cases which have resulted from depressing emo- tions, such as grief, fright, etc. ; cases attended by sighing, sob- bing or a disposition to be alone; most useful when the left side is affected; worse after eating; better when lying on the back. Hy0scyamus.—The twitchings, which are mostly local or con- fined to certain parts, as the face, the eyelids, the arm, etc., are especially violent and jerky; disposed to laugh and be talkative; is extremely silly and agitated; worse after eating, which is performed hastly. Tarantula-—Choreic movements general, or else crossed, as the right arm and left leg; head drawn downward; involun- tary discharges of urine; grimaces of the mouth; is in con- stant motion; can run better than walk; trembling of the body; movements continue even at night, but subside under the in- fluence of music. Calcarea carb.—-Scrofulous habit, light hair, blue eyes, cold, damp feet; involuntary movements often limited to one side CHOREA. 155 of the body; apt to stumble or fall down; sore eyes; white stools; bloated abdomen. Cuprum.-——Legs and arms in perpetual motion, with constant motion of the muscles of the face; delicate constitution; face and tongue pallid; irregular movements commence in one limb and spread to other parts, sometimes involving the whole body, at others limited to only one side of it; great mental exaltation; better when lying down or when asleep, but never cease altogether. Zincum.—- Chronic chorea, embracing all the voluntary muscles of the face, trunk and limbs, so that she was unable to eat, walk or lie; had had all kinds of treatment, embracing chaly- beates and other tonics; general health greatly impaired. Stramonium.-—-Crossed, irregular movements of the voluntary muscles, as, for example, the right arm and left leg; head and neck in constant motion; patient leaps about, making the 1nost grotesque gestures; weeps, laughs, sings, prays, stammers and does many silly and unusual things; handles the genital or- gans; is violently agitated by unfounded fears; not disposed to talk, or unable to do so; the involuntary movements greatest when awake, but may continue when asleep. Asterias rub.——Trembling and jerking movements of all the limbs, rendering her unable to feed herself or to walk; fre- quent, clear, profuse 1nicturition; from fright and mental de- pression. Sulphur. -— Chronic cases, and after suppressed eruptions; in one case the patient was disposed to admire common objects, raving over them; she was pale and poorly nourished; had existed six months; patient is apt to be irritable, peevish and obstinate. Veratrum vir.—Choreic movements approach the form of eclampsia, are very violent and continue during sleep; waked up by a continual champing of the teeth; lips covered with foaming saliva; inability to swallow; great sexual excitement. Cina.—Violent twitching of the muscles, with scintillation of the eyes, which flash like those of a snake; the choreic move- ments commence with a shriek; tongue, larynx and oesoph- agus affected, causing a clucking sound, like that of water poured from a bottle; when caused by worms or onanism. 156 NERVOUS THERAPEUTICS. Cicuta.—Twisting, jerking and distortion of the limbs, some- times accompanied by screams; sudden rigidity of the limbs. Auxiliary Treatment.--Care should be taken to remove, as far as possible, all exciting causes of the disease, such as in- testinal worms, pernicious practices, irregular hours, over- stimulation of body and mind, etc.; and as the disease is essentially one of nervous debility, we should aim to strengthen and build up the system by nutritious diet, Pure air, sunshine, regular hours, freedom from excitement, and such other hy- gienic influences as the casein hand may require. Care should also be taken not to allow the patient to associate with others similarly affected; neither should the patient’s mind be allowed to dwell upon the disease. Choreic patients should never be scolded, as they have very little, if any, control over their move- ments, and harsh words will do far more harm than good. Chorea arising from spinal irritation will be benefited by the treatment recommended for that disease, which see. Elec- tricity is highly lauded by some authorities. Benedict says that out of twenty cases that he treated with the constant current not one failed to recover; others, however, have been less successful with it. Hysterical chorea requires the special treatment recommended for hysteria, which see. HYSTERIA. Syn0nyms.——Hysterics, Hysteric Fit, Vapors, Malum Hys- tericum; Fr., Hystérie, Maladie Imaginaire, Mal de Mere; Gen, Hysteric, Mutterbeschwerde. Definition.—-A disordered state of the nervous system, tend- ing to chronicity, characterized by acute attacks of functional spasm and paralysis, anaesthesia and hyperaesthesia, resulting from irritative impressions, sometimes mental and sometimes physical, acting on the emotional centres of the brain. Diagnosis.-—The diagnosis of hysteria, multifarious as are its symptoms and manifestations, resolves itself simply into the detection, as such, of a purely emotional disease. This, as a general rule, is not difficult, provided the observer bears in mind that the phenomena are, in most cases, imperfect imita- HYSTERIA. 157 tions of real diseases. In nearly every case there is something either contradictory or exaggerated about them which betrays at once their real character. Occasionally, however, owing to the nature and gravity of the symptoms, it becomes necessary to distinguish carefully between a fit of hysteria and one of epilepsy, of hystero-epilepsy or of puerperal convulsions. The following table gives the differential diagnosis between hys- teria and epilepsy : Hysteria. Epilepsy. Loss of consciousness gradual and par- tial or apparent. Face flushed or unchanged, no froth on lips, eyelids closed, eyeballs fixed, no grinding of teeth or biting of tongue; pupils react readily. Countenance not distorted. Sighs, laughs or sobs. Globus hystericus. Paroxysm longer than in epilepsy, usually wakeful and depressed in spirits. Rarely occurs at night. Often connected with uterine or men- , strual disorders. Hystero-Epilepsy. Pressure upon the ovaries will fre- quently arrest the paroxysm. Thermometer never rises above 38.5° C. Sudden and complete. Livid face, froth at mouth, eyelids half open, globes rolling, teeth grind- ing, tongue bitten; more or less insensibility of pupils to light. Countenance distorted. Shows no feeling. Aura epileptica. Short paroxysm, followed by heavy, comatose sleep and dull intellect. Frequently occurs at night. Not necessarily connected with the uterus, though a paroxysm often occurs at the menstrual period. Will never modify or stop the attack. Thermometer always rises above 38.5° (3., sometimes sev eral degrees higher. Hysterical convulsions may be distinguished from puer- peral eclampsia, not only by the previous history of the case, but by the presence in the latter of complete unconsciousness and albuminuria. Hysterical paralysis may be distinguished from the various forms of cerebral and spinal paralysis by the symptoms peculiar to the latter. This will sometimes neces- sitate a continued watching of the hysterical disorder, which is usually more variable and more influenced by emotional excitement than the true disease. 158 NERvoUs THERAPEUTICS. Path0l0gy.—-Although no constant pathological alterations have yet been discovered in either the brain or spinal cord, the symptoms show clearly that both of these great nerve- centres are involved in every well-developed case of the dis- ease. The psychical and emotional symptoms point unmis- takably to the brain as their origin, while various forms of spasms, paralysis and hemi-anaesthesia can only be explained by referring the centre of diseased action to the same organ. In like manner the primary centre of reflex action can, in many cases, be traced directly to the spinal cord, the reflex action gradually spreading from the seat of irritation so as to involve adjacent groups of muscles under the control of that organ. That the peripheral nerves are not the primary seat of the hyperaesthesia is shown by the fact that the symptom has continued to exist after the affected limbs have been amputated. These considerations, as well as others equally conclusive which might be adduced, prove that the cerebro- spinal centres are the parts especially involved in the irritation which disturbs the harmonious action of the various parts of the nervous system in this disease, but what the special condi- tion of these centres is, whether one of congestion, anaemia or some change analogous to that which gives rise to insanity or epilepsy, is as yet undetermined. Clinical Experience.——Ignatia amara comes so near to being a universal specific for hysteria that one seldom has occasion to resort to any other remedy. Gelsemium, Bella- donna, Aurum, Uimicifuga, Nux vom., Moschus, Sepia, Aconite, Lachesis, Chamomilla, Pulsatilla, Phosphorus, Valerian, Platina, Asafcetida, Stramonium and many other remedies have proved curative in particular cases. Therapeutic Indications:-These will be found under the several diseases simulated by the disorder, especially convul- sions, spinal irritation, paralysis and neuralgia, which see. Auxiliary Treatment.-—-Whatever may be one’s opinion as to the essential nature of this disease, no one will deny that in the great majority of cases the mind exercises a controlling influence over it; it follows, therefore, that moral treatment is of paramount importance. Many cases have been cured by HYSTERO-EPILEPSY. 159 one physician which had resisted the treatment of other prac- titioners equally competent, simply because the former, unlike the latter, had enlisted the patient’s exertions in her own behalf. To do this the physician needs, first of all, to acquire the respect and confidence of his patient, after which he has only to direct and his directions will be obeyed ; but if, on the other hand, he fails in this regard, either through lack of tact or otherwise, his directions will most likely be ignored, if not entirely reversed. Besides, the co-operation of the patient is all the more necessary in order to successfully overcome the bad habits and banish the hurtful influences which are almost invariably associated with and tend to perpetuate the disease; such as the various forms of dissipation connected with fash- ionable life, the use of stimulants, late hours, unwholesome reading, unsuitable occupations, the injudicious kindness of home friends, whose mistaken sympathy often leads them to foster rather than to counteract the natural inclinations and morbid desires of the patient. We have not the room to enlarge further upon this fruitful topic, but are free to say that unless the practitioner has the tact to overcome these difficul- ties his efforts to cure his patient will, nine times out of ten, result in utter failure. HYSTERO-EPILEPSY. Synonyms.——-Epileptiform Hysteria; Fr., Hysté9'0-l*jp2Ileps’£c,- Hg/stérie Ep'ileptzf0rme,' Ger, H1/steroepilepsie. Definiti0n.—An unusually grave form of hysteria, the violence of the convulsions resembling that of epilepsy, and characterized by the most intense and remarkable forms of anaesthesia, paralysis and muscular contraction. Diagnosis.—Hystero-epilepsy differs from simple hysteria chiefly in the intensity of the symptoms, which give an epilep-' tiform character to the paroxysms. It differs from pure epi- lepsy in never, even when of many years’ duration, leading to dementia; the intellect always remains unimpaired. The epi- leptic group of symptoms is never complete, and never appears in connection with, or under the form of, the petit mal; it never 160 NERVOUS THERAPEUTICS. assumes the form of vertigo-epileptique. Compression of the ovaries always modifies the attack, and sometimes completely arrests its effects, which results are never produced in true epi- lepsy. In hystero-epilepsy, even when the disease lasts a long time, the thermometer never rises above 385° C.; while in true epilepsy, under similar circumstances, the thermometer rises much higher than this, even when the disease is not compli- cated with cerebral or meningeal congestion, in which latter case the temperature still continues to rise until it may indi- cate a fatal termination. Path0l0g‘y.—As the same causes that give rise to hysteria operate to produce hystero-epilepsy in certain neurotic consti- tutions, the pathology of the disease is no doubt of the same general character; the only difference, so far as our present knowledge extends, is that the ovaries constitute the special primary centres of reflex irritation, whence originate the cerebral and spinal symptoms. The blood, also, may be more or less depraved, as in simple hysteria, but this point has not yet been definitely settled. Clinical Experience.—The remedies which have so far given the best results in hystero-epilepsy are: Cannabis ind., Ig- natia, Gelsemium, Amyl ‘nit., Moschus, Tarantula and Hyoscyamus. Therapeutic Indications.—— The same as in convulsions, spinal irritation, epilepsy and hysteria, which see. Auxiliary Treatment.—MM. Charcot and Bourneville have obtained curative results by the continuous application of the ice-bag compress over the ovarian region. Whenever there is an ovarian aura the breaking out of the fit can be prevented by it. Dr. Petit has treated the disease successfully by metallo- therapy. He gives Aurum chlor. internally, and places disks of gold on the limbs, causing in one case a complete cure, so that within a year after the commencement of treatment the patient married. In this case the left arm was contracted during two years, there were general amyosthenia and anaesthenia, and the patient suffered intensely from ovarian pain, vomiting and spasmodic contractions of various muscles, including those of the oesophagus and vagina. CATALEPSY. 161 GATALEPSY. Synonyms.—Morbus Attonitus, Carus Gatalepsia, Hysteria Cataleptica; Fr., Catalepsie; Gen, Convulsivische Starrsucht. Definition.—A peculiar form of nervous disease, allied to hysteria, occurring in paroxysms, and characterized by a loss, more or less complete, of consciousness, sensibility and volun- tary motion, during which the limbs are rigid and remain in the exact position in which they chanced to be at the moment of attack, or in that in which they are afterwards placed. Diagnosis.—The above definition is sufficiently precise to prevent the possibility of mistaking this disease for any other, unless it be some other hysteroid affection, such as ecstasy, hysteric unconsciousness, etc., a matter of no practical impor- tance, as these conditions are all of a similar nature and fre- quently pass from one into the other. Path0l0g'y.—As in hysteria there appears to be a partial loss or diminution of will power, so here the controlling power of the will appears to be completely lost; in other words, there is not only loss of consciousness and sensibility, but complete paralysis of the will. “My sensations,” said one who had recovered, “ were too feeble .to call forth an exercise of will.” That this is the true explanation is proved by the fact that the condition can be produced artificially. Gharcot and others have shown that when thrown into the hypnotic state the cataleptic condition can at any moment be brought about by the mere suggestion that the subject no longer has any power to move his own limbs. Clinical Experience.—The only remedies I can find to which cures have been attributed are: Cannabis ind., Artemisia vulg. and Aranea diad. Therapeutic Indications.—Same as in hysteria, which see. Auxiliary Treatment.—According to Prof. Bosenthal, Faradization of the face by metallic conductors not only re- stored the consciousness, but brought about complete recovery from a cataleptic attack in a woman whose death had already been certified by a country practitioner. 162 NERvoUs THERAPEUTICS. MULTIPLE CEREBRO-SPINAL SCLEROSIS. Syn0nyms.—Disseminated Cerebro-spinal Sclerosis; Fr., Sclérose en Plaques Disséminées ; Ger., Multiple Cerebro-spinale Sklerose. Definition.——A disease characterized by overgrowths of neu- roglia, in the form of plates or nodules, of varying size and shape, disseminated throughout the spinal cord, and also through different parts of the brain. Diagnosis.—The most characteristic mark of this form'of sclerosis is the universal trembling which ensues on voluntary movements, and the fact that the trembling of the head, of the upper and lower extremities, as well as of the whole body, is considerably increased with every motion. Even the tongue trembles when the patient is requested to protrude it, while disturbances of speech are a constant characteristic clinical symptom. Pathology.—In describing other forms of sclerosis we have repeatedly stated that the essential morbid process consists in hypertrophy or proliferation of the neuroglia, at the expense of the proper nerve-tissue. In this form the sclerosed tissue appears, as above stated, in the form of plates or nodules in different parts of the brain and spinal cord. Treatment.—See the various forms of cerebral and spinal sclerosis, including locomotor ataxia, pp. 42, 102-107. SECONDARY CEREBRO-SPINAL SCLEROSIS. Syn0nyms.—Secondary Cerebro-spinal Degenerations, Sec- ondary Degenerations of the Spinal Cord, Ascending and Descending Degenerations; Fr., Dégenérations Secondaires de la Moelle lfpiniere ,' Ger., Secondiire Erkrankung Einzelner Rilcken- marksstrcinge, Seconddre Cerebro-spinale S klerose. Definiti0n.——Sclerotic degenerations affecting certain por- tions of the cerebro-spinal axis, resulting from trophic lesions situated either in the brain or spinal cord; if in the former they give rise to descending degenerations, if in the latter to ascending ones. / GENERAL, PARALYSIS. 163 Dia,gnosis.——Secondary cerebro-spinal sclerosis may be diag- nosed by the concurrent existence of the foot phenomenon, the tendon reflex and the phenomena of associated movements. Pathology-The degenerative changes are usually confined to the white substance, and consist in atrophy and degeneration of nervous filaments, the formation of granular corpuscles and the characteristic proliferation of the neuroglia. When the gray matter is involved the nerve-cells undergo more or less disintegration and wasting; muscular atrophy is then asso- ciated with the rigidity and contraction resulting from de- generation of the white substance. Treatment.—(3onsult the various forms of cerebral and spinal sclerosis already given, especially locomotor ataxia, pp. 42, 102- 107. GENERAL PARALYSIS. Syn0nyms.—General Paresis, Paralysis of the Insane, De- mentia Paralytica; Fr., Paralysie Générale Incomplete, Périen- céphalite Chronique Difl'use; Ger, Allgemeine Progressive Gehirn- lélhmung, Paralytischer Bl5clsirm. Definition.—-A general paretic condition, accompanied by gradually increasing mental disturbance, incoiirdination of movement and loss of physical power. Diagnosis.—The diagnosis is based upon the presence of convulsive tremors in the muscles of articulation at the com- mencement of the disease, the general and progressive paresis and loss of coordination, and the peculiar mental manifestations of aberration and extravagance. Path010gy.—There are usually more or less congestion and inflammatory thickening of the cerebral membranes, atrophy and degeneration of the cortical substance, especially of the anterior lobes, and wasting and amyloid degeneration of the ganglion cells, with hypertrophy of the neuroglia. Similar changes also occur in the posterior columns of the spinal cord, the cerebral nerves and the posterior roots of the spinal nerves. In some cases there are signs of granular myelitis; large masses of fat globules, with hypertrophy of the septa of the cord. It thus appears that the disease is a diffuse inflamma- 164 NERVOUS THERAPEUTICS. tion of the brain and spinal cord, leading finally to destruction of ganglion cells and atrophy of the nerve-centres. Clinical Experience.—/irgentum nit. and Plumbum are entitled to the distinction of having arrested the degenerative process. Belladonna, Physostigma, Cocculus ind., Badiaga, Oxalic ac., Causticum, Gelsemium, Rhus ton, Phosphorus and a number of other remedies have ameliorated many of the symptoms. Treatment.——See meningitis, encephalitis and the several forms of paralysis and sclerosis already described, especially locomotor ataxia. PARALYSIS AGITANS. Syn0nyms.—Shaking Palsy; Fr., Paralysie Agitante, Para- lysie T remblante; Gen, Schilttelldhmung. Definition.—A disease of the nervous system, characterized by tremor of the voluntary muscles, followed by paralysis of the same, both being progressive in their course. Diag'n0SiS.—Paralysis agitans is liable to be mistaken for chorea, senile tremor and multiple sclerosis. From the first it may be distinguished by the age of the patient and the history of the case; fro1n tremor senilis, from being a disease of middle life instead of old age, and by its beginning on the head and attacking successively the lips, tongue and extremities; and from multiple sclerosis, by the latter being a disease of youth, and the tremor appearing only when motions are intended, whereas, in paralysis agitans, the tremor, though it may be increased from an intention to motion, or from mental excitement, is also observed during perfect rest. ‘ Very rarely a case is seen, and it may even run its course, without any tremor being present. In these cases the disease is recognized by the other characteristic symptoms, such as fixed attitude, slow, delayed movements, difliculty in rising from the sitting posture, retropulsion, apropulsion, monotonous and mumbling speech, etc. ‘ Path0l0gy.—No characteristic pathological changes have yet been observed sufficient to account for the symptoms of this disease. Various coarse lesions have not infrequently been met with in both the brain and spinal cord, but those PARALYSIS AGITANS. 165 hitherto observed have been such only as are frequently pres- ent in those who die of old age where no such symptoms are present. Although in many cases, however, the results have been negative, the fact that some observers have found sclerosis in various parts of the brain and spinal cord renders it highly probable, I think, that a certain degree of hypertrophy of the neuroglia constitutes the essential element of the disease. Clinical Experience.—-I can find none of‘ our remedies to which cures of this disease have been attributed except Plum- bum, Mercurius and Tarantula. Good results, however, have followed the administration of Argentum nit., Baryta carb., Hyoscyamus, Physostigma and Zincum. Treatment.—-Compare the various sections devoted to pa- ralysis and sclerosis, especially multiple cerebral and posterior spinal sclerosis, pp. 42, 107. PART IV. DISEASES OF THE PERIPHERAL NERVOUS SYSTEM. NEURITIS. Syn0nyms.——-Inflammation of a Nerve; Fr., Névrite; Ger., Entzilndung der Ncrven, Nerventzilndung. Diagnosis.—The pain does not intermit as in neuralgia, neither is it excessive, except in traumatic acute neuritis. The disease may also be distinguished from neuralgia by the in- creased temperature of the part to which the nerve is distrib- uted, and by the history of the case. Anaesthesia, spasm and paralysis, which are common symptoms of neuritis, are absent in neuralgia. From cerebro-spinal diseases, in which these symptoms are present, it may be known by the circumscribed limits of the disease and by the absence of central symptoms. Pathology.—The pathological changes are chiefly confined to the neurilemma or connective-tissue sheath of the nerve, which is found to be more or less injected and hyperaemic. Microscopical examination reveals, in addition to the increased vascularity, inflammatory proliferation of new tissue-elements with migrated leucocytes. These changes necessarily produce either irritation, or arrest or disturbance of nerve function, through compression of the nerve tubules by swelling of the nerve-sheath. Clinical Experience.——/lconite, Belladonna and Hypericum have proved curative in the early stages of acute cases; trau- matic cases usually yield promply to the internal and external use of Hypericum perf. and Calendula. Auxiliary Treatment. -—-The wet compress, hot fomenta- tions and ice, locally applied, all have their advocates in this disease. The new operation of nerve-stretching may be of benefit in chronic cases. (166) NEURALGIA. 167 NEURALGIA. (IN GENERAL.) Syn0nyms.—Nervous Pain, Neurodynia; Fr.,, lVéoralgie; Ger, Neuralgie. Definition.—A functional disease of the nerves, almost always unilateral, usually confined to the origin, course or termination of one or more nervous trunks or branches, and unaccompanied by fever, inflammation or any appreciable organic lesion. Diagnosis.—The diagnosis of neuralgia is not usually at- tended with any difficulty. When the pain takes the course of a nerve we know at once that it is neuralgic, but when it is confined to an organ, space or spot, other circumstances have to be considered: (1) the pain is always more or less paroxys- mal; (2) it usually begins suddenly, is of a darting, lancinating or boring character, and is confined to the course of the nerve and its several branches; (8) the paroxysm develops sponta- neously or without any marked exciting cause; (4) puncta do- lorosa are observed in the majority of cases somewhere in the course of the nerve; and (5) vaso-motory, trophic and other disorders are occasionally associated with it. PM3h0l0gy.——The disease, per se, is a purely functional affection, but many cases occur in which there is reason to think that inflammation of the nerve-sheath is the starting point and proximate cause of the disease. This is often the case in sciatica, which is more frequently, perhaps, a peri- neuritis than a pure neuralgia. In these cases the pain is much more constant, that is, less paroxysmal than usual, and is more apt to be attended by paretic symptoms. Clinical Experience.—In order to avoid undue repetition, we shall defer giving the usual therapeutic indications until we come to consider more in detail the leading varieties of the disease, substituting here a 1 general resurné of clinical ex- perience. Spige1ia.—-Sharp and cutting pains, extending over the tem- ples and forehead, with profuse flow of water from the eyes; sharp pain in the left side of the face and head, with intense pain in the eyeball. 168 NERVOUS THERAPEUTICS. Ammonium picr.—Violent boring pain in the right side of the head, spreading to the supraorbital and superior maxillary region, intermittent, commencing at 10 A.M., increasing till 2 P.M., and disappearing about 9 P.M. Hamamelis.-—Neuralgia of the internal saphcnal nerve in the ascending form; severe pain on the internal side of the right knee, radiating from the internal condyle of the femur to the crural arch; lancinating and burning pains piercing the knee and extending to the groin. Magnesia. phos.—Typical facial neuralgias; pains intermittent, darting, lightning-like, suddenly appearing and disappearing, relieved by heat and pressure. Kalmia.——Neuralgia facialis, nocturnal; sharp, shooting and twitching pains, commencing in the neck, going to the top of the head, then to the temples and right side of the face; re- lieved by cold, aggravated by heat. Pulsatilla.—-Right side of head and face; worse at night, with throbbing in the head; face flushed; external soreness; always occur when nursing.. Aco11ite.——Congestive forms of triy”acial neuralgia; pains lan- cinating and burning; great agitation. Arsenicum.--Neuralgia of the fifth ncrvc, acute; violent attacks of tearing, burning pain, occurring every five minutes both day and night, in the second branch of the trigcminus, chronic ,- lumbo-abdominal neuralgia. Rhododendron.—-Violent prosopalgia, spreading over the right side of the face from the teeth, and radiating over the mouth, eyes and ears, equally violent day and night; pains drawing, tearing, jerking; ameliorated by warmth, when eating, and for some time afterward. Mezere11m.—Dull, gnawing, sometimes severe boring pain all along the jaws and gums; cutting, shooting pain, returning every night on the left side, extending from the face to the ear, temple and neck, worse when warm in bed; severe supra- orbital, intermittent, circumscribed, diurnal pain, beginning at 9 A.M., increasing until noon, subsiding about 4 P.M., of a heavy, aching character, sometimes extending into the left eye, causing a flow of tears. NEURALGIA. 169 Lachesis.—Dull, heavy, severe pain, commencing at 9 A.M. in the inner canthus of the right eye and extending outward and upward above the superciliary ridge, going off in the afternoon; skin extremely sensitive to touch; worse after sleeping. Tartar emet.-—Severe neuralgic pains in the right leg, follow- ing the sciatic nerve, pain running from above downward; muscles of the leg felt tense. Bryonia.——Trigeminal neuralgia of the left side; pain acute, the motion necessary to speak or eat aggravated it to such an extent as to provoke a free flow of tears; severe pain in the right side of the head, face and jaws, worse in the morning, occurring during pregnancy. Gelsemium.—Severe orbital neuralgia, occurring frequently, and accompanied by heaviness and drooping of the upper eye- lids and great muscular weakness; severe paroxysms of right facial neuralgia, lasting six months; neuralgia of the anterior crural nerve, pain extending up to the iliac crest and down to the inner side of the knee, accompanied by tenderness between these points. Iris Ver.—Trifacial neuralgia in the left temporal region, ex- tending down the ramus of the lower jaw into the teeth, pain sharp and cutting. Veratrum alb.—-Neuralgia palpebrares of the right upper lid, greatly aggravated by pressure, the most delicate touch feeling as if hundreds of needle points were penetrating the cuticle of the lid; colic-like pains, followed by diarrhoea. Sabina.——Facial neuralgia depending on paramenia; general neuralgia, occurring one week prior to menstruation, accom- panied by frequent shudderings, burning heat in the whole body and great nervous irritability. Bismuthum.——Severe facial neuralgia ; pains burning, and greatly aggravated by warmth; relieved by holding cold water in the mouth. Natrum mur.—Facial neuralgia of malarial origin; pains begin about 8 P.M. in the region of the right eye, the right side of the nose and the right frontal region, accompanied by high fever, great thirst and some nausea, subsiding with the abate- ment of the fever, and returning again the next evening. 12 170 NERvoUs THERAPEUTICS. Zincum phos.--General neuralgia depending on nervous de- bility; neurotic constitution; loss of memory; loss of sleep from continued mental anxiety. Kali cyan.—-Left supraorbital neuralgia, beginning daily at 9 A.M., reaching its height in less than an hour, and gradually declining just before noon, the decline being accompanied with considerable nasal discharge. Aranea diad.—I/umbo-abdominal neuralgia of a remittent character, exacerbation occurring between 8 and 11 A.M., and continuing until evening, attended at its height by excessive yawning, and at times by vomiting. ' Plumbum met.—Neuralgia of the rectum; pain of a drawing, gnawing character, worse toward evening and at night. Kali bich.—Infraorbital neuralgia; pain aggravated by mo- tion, and especially by cold. Conium.—Infraorbital neuralgia; tearing, cramplike pains, occurring in the evening and at night; mastodynia. Nux V0m.—Supra0rbital neuralgia of an intermittent char- acter; sudden, agonizing, lightning-like pains, coming on in the morning and aggravated by pressure and motion. Colchicum.—Facial neuralgia, involving especially the infra- orbital nerve ; pains of a tearing character, and accompanied with trembling and twitching of the lips and muscles of the face. Auxiliary Treatment.—-Special attention should be given to nutrition, especially in obstinate cases. Romberg’s theory that “ neuralgia is the prayer of the suffering nerve for healthy blood and more of it,” has been abundantly verified. Hence patients suffering from debility (and nearly every such patient is more or less debilitated), scrofula, tuberculosis, or any other dyscrasic condition, should push the nutritive process to the utmost. One of Pretz’s patients ate twelve times in twenty- four hours and improved under it. Tuberculous cases are usually benefited by a course of cod-liver oil. Phenacetine and other analgesic palliatives may prove more or less useful in obstinate cases. Electricity, nerve-stretching, compression, sea-bathing, hot fomentations and the local application of Aconite, Menthol TRIGEMINAL NEURALGIA. 171 and other stimulating and rubefacient applications have all done good in special cases. Gussenbauer ascertained that the great majority of trifacial neuralgias are due to reflex irritation, While some cases follow from sexual disease, malaria, tobacco poisoning, etc., ninety per cent. of trigeminal neuralgias result, he says, from habitual constipation, and may be treated suc- cessfully by cold water enemata and hydrotherapy. TRIGEMIN AL NEURALGIA. Syn0nyms.——Neuralgia of the Fifth Nerve, Facial Neu- ralgia, Prosopalgia, N euralgia Trigemini; Fr., Tie-Doaloureux; Ger, Neuralgie des Filnftenerven, Neuralgie der T rigemirms. Definiti0n.—Neura.lgia of one or more branches of the tri- facial or fifth nerve. Diagn0Sis.—Trigeminal neuralgia is most likely to be con- founded with hemicrania. It may be readily distinguished from it, however, by the transient and shooting character of the pains.and by their corresponding with the course and distri- bution of the different branches of the nerve. It is important, also, to distinguish trigeminal neuralgia fro1n odontalgia, as many a sound set of teeth have been needlessly sacrificed to cure a supposed neuralgia which did not exist. In toothache the pain is usually continuous, or it is made worse when some of the teeth are subjected to pressure or to cold, and if closely examined defective places may be found in them. Pttth010gy.—The most diligent search has often failed to find anything abnormal about the trunk of the nerve or any of its branches. It is quite certain, however, that the sym- pathetic nerve is sometimes implicated-in the attacks, for in no other way can we explain such symptoms as contraction of the pupils, conjunctival injection, flushing of the face and the constitutional disturbances sometimes met with ; but it is not always certain whether these phenomena originate in the sym- pathetic system or are secondary to the trigeminal disease. Clinical Experience:-See the preceding section. Therapeutic Indications. —— Arsenicum. — Severe burning pains, as if made with hot needles; pains appear toward night 172 NERVOUS THERAPEUTICS. and reach their greatest intensity near midnight; the anguish is sometimes so great as to compel the patient to get up and walk about; aggravated by noise and motion, also by cold water, which at first relieves; ameliorated by hot applications. Mezere11m.—Pains appear suddenly on moving the jaws, espe- cially on eating hot things; stiffness of the muscles of the neck; aggravated by the lightest touch, but diminished by hard press- urc; may affect any or all three of the trifacial branches. Kali carb.-—Burning pains, with twitching of the muscles, affect- ing preferably the mental and infraorbital branches; pains accompanied by beating of the temporal arteries; aggravated by eating sour fruit or by mental excitement. Nux vom. — Lightning-like pains, with twitchings of the affected parts; violent, agonizing pains, obliging the patient to change his position frequently or to walk about ;pains sometimes diminish on remaining quiet or on lying down. Guprum-—Lightning pains, with violent throbbing of the temporal arteries and great anguish; pains aggravated by touch. Thuja.—Acute shooting pains throughout the course of the infraorbital nerve, producing flashes of heat in the face and a sensation of internal heat; cramping pains, with muscular twitchings; convulsive movements of the upper lip accompany the exacerbations of pain ; ameliorated by motion and by the open air. Bry0nia.—Severe aching and shooting pains, which may ex- tend to the ear, involving especially the left inferior dental branch; teeth and gums sore ; sometimes, but not always, re- lieved by warmth ; aggravated by chewing and by cold. Ignatia.——Violent, agonizing pains, affecting especially the supraorbital nerve, occurring in sudden, short jerks, diminish- ing or disappearing on moving the affected part, but immediately returning; usually aggravated by pressure. Aconite.-—Lancinating and burning pains, accompanied by painful tingling and prickling, redness of the affected parts and restlessness; pains sometimes relieved by strong friction, but aggravated by motion. Phosphorus. —Lancinating, lightning-like pains, affecting TRIGEMINAL NEURALGIA. 173 chiefly the infraorbital nerve, and accompanied by twitchings in the affected part; pains excited by the least movement of the part, especially by mastication, so much so as to cause the patient to refrain from eating or drinking. Spigelia.—Pains extend to the eyes, which are more or less injected, and seem to be compressed in the orbit; pains aggra- vated by the slightest touch or movement. Zinm1m.—Lightning pains, with muscular twitchings, affect- ing any or all three branches; eyes appear sunken, eyelids bluish, face pale, tongue congested; pain increased by pressure. Argentum nit.——Pains of a sudden, rending character, extend- ing into the orbit; globe feels as if it would be pressed out; face pale, sight impaired, affected parts somewhat anaesthetic. Belladonna.—Outting, throbbing pains, frequently extending into the eye and temple, or into the ear; affecting especially the right side of the face; worse in the afternoon and evening; aggravated by motion, light and noise. Sepia.—Drawing, tearing pains, extending to the teeth, ver- tex and occiput, worse in the left side and at night; pains fre- quently extend to the ear; aggravated or renewed by either warmth or cold; suited to delicate, sensitive women, especially when caused by cold, or when the menstrual function is dis- turbed. The following remedies may also be indicated: Uoflea, Glonoin, Causticum, Stannum, Colocynthis, Verbascum, Chamo- milla, Chininurn sulph., Cimicifuga, Graphites, Rhus tocc. and Lyce- podium. Auxiliary Treatment.—Galvanic electricity is frequently of great benefit during the paroxysm, often relieving the most intense suffering at one sitting. The best mode of applying it is to place the wet sponge of the positive pole over the affected nerve, and that of the negative atany convenient point out- side the painful area. The current, which should be weak at first, will be most effective by being gradually increased until a slight sensation of heat is produced. One or two applica- tions a day, of not over ten minutes each, will be suflicient, ex- cept in chronic cases. Nerve-stretching l1as been practiced successfully in a number 174 NERvoUs THERAPEUTICS. of instances, especially in the case of the supraorbital nerve, sufficient force being applied to liberate the nerve from any inflammatory or other form of compression, which may have interfered with its normal function. There.is no better local application in these cases than a solution of Aconitia, one grain to the ounce, which may be painted over the painful nerve with a camel’s hair brush when- ever required; or the strong tincture of Aconite may be rubbed in along the course of the nerve until the part becomes numb‘, repeating the process pro re nata. MASTODYNIA. Syn0nyms.—Neuralgia of the Mammae, Mastalgia; Fr., Névralgie des Mamelles ; Ger., Neuralgie der Brustdrilsen. Definition.—Neuralgia and hyperaesthesia of the mammary glands. Diagnosis.——The disease is often confounded with inter- costal neuralgia, which is but one of its various forms. Some- times the slightest touch causes pain (hyperaesthesia); at others, the deeper structures are involved, and the affection partakes more of a neuralgic character. Pathology:-The pathology of mastodynia is obscure. Sometimes small points on the glands are sensitive to pressure, due, probably, to enlargement of nerve-fibres. In other cases the affection appears to be seated in the dorsal region of the spine, from which the nerves supplying the mammary glands are derived. The constitutional conditions which give rise to it are, in the main, similar to those which favor neuralgia in other parts, namely, anaemia, chlorosis, hysteria, etc. Its relation to the sexual sphere is shown by its frequent associa- tion with disturbance of the sexual organism, especially at the menstrual period. Clinical Experience.—-Phytolacca.-When complicated with hyperaemia of the mammae; the breasts are swollen and very sensitive to pressure, cannot bear to have them touched; neuralgic pain in the left ovary; worse during menstruation and lactation. t coccreonvnm. 17 5 Bryonia.-—When every movement of the arm causes pain in the corresponding mamma; also when complicated with ovaritis. Arsenicum.—Periodical attacks, especially when complicated with malaria; also when the pain is relieved by heat and aggravated.by cold. Rhus t0x.—()ongestion of the mammae; the breasts feel hot and dry; the glands are swollen, and the pain is deep-seated, of an aching character and relieved by manipulation. Pulsati1la.—When associated with menstrual derangement, or when there is a constant feeling of chilliness. Aconite.-—Cutaneous hyperaesthesia; great restlessness and irritation, especially in young girls. Cham0milla.—Breasts hard and painful to the touch; hot perspiration under the mammae. Cimicifuga.——-Prickling sensations in the mammae; when associated with characteristic menstrual symptoms, or with pain in the head and back. Compare, also, Conium, Calcarea carb., Kali carb., Nitric ac., Caladium, Murex. Auxiliary Treatment.—- Fomentations, especially when medicated with the indicated remedy, are of great value in relieving the paroxysms of pain. Inunction of the breast with oil and quinine is said to be beneficial when the neuralgia alternates with neuralgia of other parts. It is also recom- mended to spray the mammae with cold water two or three times a day, employing friction afterward until the surface is brought to a glow. GOGGYGODYNIA. Syn0nyms.—Neuralgia of the Coccyx, Coccyodynia, Coccy- dynia; Fr., Doalear de Coccyx; Ger., Kreuzenclschmerz. Definiti0n.—Pain, apparently of a neuralgic character, in the vicinity of the coccyx. Diagnosis.-—As the disease is almost exclusively confined to women, and sometimes occurs after difficult parturition, it is liable to be mistaken for hysteralgia. It may be distin- guished from the latter by the fact that the patient cannot 176 NERVOUS THERAPEUTICS. bear the least pressure on the os coccygis, whereas in hysteralgia the favorite position is one that throws the entire weight of the body on this very part. Pathology,—The disease is sometimes due to neuralgia of the coccygeal plexus, but this is not always the case. On the contrary, there is reason to believe that it is sometimes of a rheumatic and sometimes of an inflammatory nature. Clinical Experience. —— The remedies which have been most frequently prescribed for this affection are: Cicuta, Acidum fluor., Ruta, Zincum, Rhus rad., T huja, Conium and Carbo an. Therapeutic Indications.—Gicuta.—Tearing, jerking pains in the coccyx; stiffness in the lower limbs; when resulting from injury or pressure during confinement. Acidum fluor.—Periodical aching in the coccygeal region; aching pain in the os sacrum and lumbar region, relieved by pressure, stretching and bending backward, especially the former. Ruta.——Pain extending from the coccyx to the sacrum, as if caused by a blow or bruise. Zincum.—-Aching, pinching and lancinating pains in the coccygeal and sacral regions; pressure, tension and weakness in the sacral and lumbar regions; back cracks when walking. Rhus rad.—Pain in the loins and lower spinal region, espe- cially when moving the hips or when lying in bed at night; rheumatic cases, attended with a sense of weariness and lan- guor, with stiffness. Tarantula.—-—-Burning, smarting and painful uneasiness in the coccyx after confinement, better when standing, worse from slightest pressure or motion. Thuja.—Painful drawing sensation in the coccygeal and sac- ral regions and in the thighs, when sitting; sudden cramping pain in the lumbar region after long standing, and when at- tempting to walk it seems as though he would fall; after being seated awhile the drawing becomes so great as to hinder stand- ing erect. Gonium.—Drawing and stitching pains in the lumbar, sacral and coccygeal region, followed by great weakness and nausea; drawing through the lumbar vertebrae when standing. SCIATICA. 177 Garbo an.—Pain in the coccyx, which burns when the parts are touched; pain as from subcutaneous ulceration, worse on sitting or lying down; pressing, bearing-down pain in the coccyx, as if bruised. Consult, also, Silicea, Belladonna, Rhus tox., Causticum, Cistus can., Graphites, Paris quad, Kreosotum, Cantharidis, Petrolium, Magnesia, Phosphorus, Lachesis, Muriatic ac. and Cannabis sat. Auxiliary Treatment.—Extirpation of the coccyx has been resorted to in very obstinate and painful cases, also subcuta- neous section of the attached muscles and ligaments. Such ex- treme measures, however, are seldom necessary, as the homoeo- pathically indicated remedy, aided, if necessary, by electricity, will cure the most rebellious cases. We have the testimony of Rosenthal that electricity alone cured a case of twelve years’ standing. SCIATICA. Synonyms.-——Ischias, Femero-popliteal Neuralgia ; Fr., Névralgie Sciatique; Ger., Hitftweh. Definiti0n.—Neuralgia of the parts supplied by the great sciatic nerve and its posterior cutaneous branches. Diag'n0sis.—Sciatic neuralgia is liable to be mistaken for rheumatism and for inflammation seated in and about the hip- joint. In the former case the pain is not spontaneous as in sciatica, but is always dependent on muscular action. Hip- joint disease is common in childhood and youth, while sciatica is seldom noticed under thirty years of age. But a slowly- developed chronic inflammation, usually called chronic rheu- matism, occurring in elderly people, is what is most frequently miscalled sciatica. If the pain is not increased by pressing the surfaces of the joint together, or by gently rotating the limb, it may be, and probably is, sciatica; but it cannot be hip-joint disease. On the contrary, if the pain is made worse by this procedure, if there is great stiffness about the joint, so that the lower part of the body moves when an attempt is made to bend the hip-joint, and especially if the muscles in the vicinity of the joint are permanently contracted, then it is not sciatica, but an inflammation of the joint itself. 178 NERvoUs THERAPEUTICS. Pathology.-—There is little doubt that very many cases of sciatic neuralgia are due to rheumatic inflammation of the nerve-sheath, yet it has often happened that in cases which during life have been supposed to be examples of this affec- tion no trace of neuritis has been discovered. Be this as it may, sciatica, like every other form of neuralgia, is almost in- variably associated with a depressed state of the system, and this, as before stated, has led to the general belief that the nerv- ous system is not duly nourished. The correctness of this opinion would seem to be verified by.the fact that a rich, nutritious diet, especially one rich in fats, always proves bene- ficial to the patient. I have an old chronic case now under treatment in a lady who remains entirely free from suffering so long as she continues to take cod-liver oil, but whenever she suspends the use of it for a few weeks the disease always re- turns with great violence. Clinical Experience.—See preceding section on neuralgia in general, pp. 167-171. Therapeutic Indications.--Nux vom.—Short, tearing and jerking pains, with trembling of the affected parts; stiffness of the affected limb, with sensation of paralysis; can lie best on the sound side; sometimes the pains diminish on lying down and keeping quiet, also after midnight; although the pains are aggravated by touch and by motion, they oblige the patient to move the affected part continually. Colocynthis.--Lightning-like pains in the course of either sciatic nerve, but especially the left; aggravated by touch, motion, pressure or cold, also worse at night or when warm in bed, but ameliorated during the day by warm applications; pains accompanied by a sense of constriction; especially suited to acute cases occurring in the young. Rhus tox.—Burning and tearing pains, attended by numb- ness, formication, sensation of cold and paralytic stiffness of the affected limb; pains aggravated by rest, especially rest in bed and at the beginning of motion, but ameliorated by the con- tinuance of motion; has also cured cases aggravated by pro- longed motion. Bryonia.-—Twitching pains extending from the lumbar region SCIATICA: 179 to the thigh, with sweating; pains attended with shocks in the affected limb; pains aggravated by touch and motion, but often ameliorated by hard pressure or by lying on the affected part, also by cold water; is suited to both acute and chronic cases, even when there is atrophy of diseased limb. Gham0mil1a.——Tearing, boring pains, occurring in young and nervous persons, especially when the pain is worse at night and is accompanied by a sensation of paralytic weakness; great irritability of mind and temper. Plumbum.—Gonstant drawing and lancinating pains, in- creased by motion, heat and sudden pressure, but ameliorated by steady pressure; pains always worse at night, suited especially to chronic cases, or when there is a tendency to atrophy and paralysis. A1'senic11m.—Tearing and burning pains, with nightly aggrava- tions; ameliorated by warm applications or by rubbing the affected part; aggravated by touch and motion; sometimes relieved by motion, especially at night, when the patient has to get up and walk the floor for relief; cannot lie on the affected side, and is very restless even on the sound side; is suited to both acute and chronic cases, especially when there is marked periodicity in their recurrence or aggravation. Ignatia.—-Throbbing, intermitting pains, with fever, preceded by chilliness, with thirst; paroxysms at first tertian, afterward quotidian; chronic cases, better in summer, worse in winter; suited also to acute cases where the patient is obliged to con- stantly change his position to relieve the pain. Bellad0nna.——Severe lancinating pains, coming on in the afternoon or evening, or else worse from noon till midnight; aggravated by the lightest touch, but frequently relieved by steady pressure; worse from motion or mental excitement; better from warmth, after perspiring, when erect, or when letting the limb hang down. Kali iod.—Pain in the hip, causing the patient to limp ; nightly tearing pains in the right limb, aggravated by lying on the affected side; muscles of the affected limb spasmodi- cally contracted: pains ameliorated by rnotion; chronic cases, with nocturnal aggravation, or when caused by mercury or syphilis. NERVOUS THERAPEUTICS. Mercurius.—-Nocturnal pains in the course of the sciatic nerve, attended by nocturnal aggravation, chills, numbness, formication and tendency to sweat, the perspiration giving no relief; patient restless and constantly changing his position; syphilitic cases. Va.leria.n.—-Pains so intense that it seems as though the thigh would break; unendurable when at rest, or when sitting or standing, but relieved by walking about. Compare, also, the following remedies: Terebinthina, Lycopo- dium, Vcratrum alb., Sepia, Fcrrum, Tellurium, Nitric ac., T huja, Ranunculus, Lcdum, Gnaphalium, Argcntum nit., Calcarca carb., Coflea, Hcpar sulph., Kali bich., Arnica, Cimicifuga, Iris vcrs., * Causticum, Lachesis, Phytolacca, Gclscmium, Ruta, Stillingia, Men- yanthes, Pulsatilla, Polygonium, Natrum mur., Natrum salic. and Mczcrcum. For indications see the two preceding sections. Auxiliary Treatment.-—In addition to the accessory treat- ment given in the last two preceding sections (which see), we add the following: As regards electricity, a strong galvanic current will generally relieve those cases in which firm press- ure over the affected part causes no pain; but where there is so much sensitiveness that slight pressure produces pain, strong galvanic currents usually do more harm than good. On the other hand, those cases which are aggravated or unrelieved by the galvanic current are almost always benefited by the Far- adic or induced current, or by the static current. Hypodcrmic injections of ether have cured some cases of sciatica, three drops of ether being injected at intervals of twelve hours. Debove claims to have succeeded in all his cases, both acute and chronic, by applying along the track of the nerve a spray of methyl-chloride, the degree of cold thus produced being as low as 22°; the line of congelation soon becomes red and warm, erythema and blisters usually develop- ing, but a true eschar seldom. In cases where pressure gives relief much benefit has been derived from the application of roller bandages. The bandage should commence at the toes and extend up to the middle or upper part of the thigh. If the pain is relieved by it, it should not be removed for several days, or until a cure is effected. PARALYTIC APHONIA. 181 Extension and suspension have relieved several obstinate cases. The diet should be of the most mltritious character, con- sisting of fresh meat, mutton, beef, grime, poultry, fresh vege- tables, and a liberal supply of cream; butter and other animal fats. As in neurasthenia, “the hungry nerve cries out for food,” and if, owing to lack of power to assimilate, digestion becomes embarrassed, or if for any reason the amount of food taken is insufficient to satisfy this hunger, so that the “ cry” is repeated, we cannot do better than to supply the deficiency with maltine, or some similar preparation. PHARYNGEAL PARALYSIS. Synonyms.—Paralysis of the Pharynx; Fr., Paralysie Pha- ryngée; G'er., Schlundlcopfldhmung. Definiti0n.—Paralysis of the pharyngeal branches of the pneumogastric nerve. Diagnosis.-—Paralysis of the pharynx is usually associated with paralysis of neighboring parts, as in labio-glosso-laryngeal paralysis (which see). This is the case whenever the disease is located at the origin of the nerve in the medulla and in- volves adjacent nuclei. But the simple form may result from meningeal disease outside the medulla, from disease of the bones at the base of the skull, and is occasionally associated with diphtheria. A careful examination is usually sufficient to distinguish it from organic disease, with which alone it is liable to be confounded. Pathology.—This is sufliciently indicated under the above head. Treatment.—Remove the cause, if possible; if not, give Causticum, Gelsemium, Cocculus, Lachesis, Silicea, Cuprum, or such other remedy as may be indicated. PARALYTIC APHONIA. Syn0nyms.—Paralysis of the Larynx ; Fr., Paralysie du Larynx ; G’er., Kehllcopflélhmung, Stimmlosigheit. Definition.—Loss of voice from paralysis of the laryngeal muscles. 182 NERvoUs THERAPEUTICS. Diagnosis.-—A laryngoscopic examination will show that one or both vocal cords exhibit diminished motion, though no mechanical impediment exists. When both crico-arytenoid muscles are paralyzed the breathing is obstructed, and even when it is deep and prolonged the edges of the vocal cords are closely approximated. When the transverse arytenoid mus- cles are paralyzed, the posterior part of the rima glottidis opens in the form of a triangle. If only one vocal cord is paralyzed the voice is weak, deficient in timbre and volume, and some- times limited to only a few notes. Some forms of paralytic aphonia may be diagnosed withoutthe aid of the laryngoscope, as the reflex, the intermittent and the form caused by severe mental shocks; in this last form, although unable to articulate words, the patient is able to cough. Pathology.-—M. Bernard has shown by numerous experi- ments that while the spinal accessory specially influences the vocal muscles, and is therefore the true vocal nerve, the respiratory muscles of the larynx are under the control of the inferior and superior laryngeal nerves. He has shown, also, that paralysis of these nerves, instead of dilating the vocal ligaments, approximates them, so that every effort at inspira- - tion tends to render the passage of air through the glottis more and more difficult by obstructing the laryngeal aperture. Hence any interference with the function of the recurrent or inferior laryngeal nerve-—which is the nerve animating all the laryngeal muscles except the crico-thyroid—or with the func- tion of the pneumogastric nerve itself, or of one of its branches, may produce aphonia. Clinical Experience.-—The principal remedies for pure paralytic aphonia have been found to be Antimonium crud., Lachesis, Phosphorus, Baryta carb., Causticum, Kali bich., Cuprum met. and Gelsemium. Hysterical and nervous cases usually yield to Ignatia, Stramonium, Nux mosch., Belladonna, Nux vom., Rhus tox. and Platina. Catarrhal aphonia, which is not truly paralytic, is successfully treated with Aconite, Belladonna, Arum tri., Causticum, Gelsemium, Antimonium tart., Argentum met., Spongia, Iodatum, Mercurius, Bromium, Ammonium brom., Kali bich., etc., etc. FACIAL PARALYSIS. 183 Therapeutic Indicati0ns.—See cerebral and spinal paralysis, pp. 54, 92. Auxiliary Treatment.-—Paralytic aphonia will sometimes yield to a single application of the galvanic current; in most cases, however, several operations are required for the gradual restoration of the lost voice. As in other kinds of paralysis, the best form, usually, is the induced or secondary current (Faraclic), but complicated cases sometimes do better with the primary current. Massage, the magnetic pad and other local ' measures have sometimes proved curative, and, though seldom necessar ma be tried in obstinate cases. 7 FACIAL PARALYSIS. Synonyms.—Bel1’s Paralysis, Paralysis of the Portio Dura, Histrionic Paralysis; Fr., Paralysie Faciale, Diplegie Faciale; Ger, Diplegia Facialis, Gesichtslcthmung. Definiti0n.—Paralysis of the facial muscles from disease or injury of the portio dura or of its nucleus. Diagn0sis.—As -facial paralysis is often associated with hemiplegia, it is important to distinguish it from that disease. In facial palsy it is impossible for the patient to close his eye on the paralyzed side, which is not the case in the cerebral form. If the fifth nerve is paralyzed, and the patient be re- quested to close the jaws firmly, the muscles of the sound side will contract more energetically and promptly than those of the affected side; and if the third nerve is implicated there will be ptosis, with dilatation of the pupil and divergent stra- bismus. Pathology.—In all cases lasting 1nore than a few days evidences of defective nutrition may be detected in the nerve- trunk as it emerges from the stylo-mastoid foramen. The fibres within the pons, and the nucleus beneath the fourth ventricle, are sometimes damaged by tumors, haemorrhage, softening, etc. The nerve sometimes becomes inflamed from the extension of inflammation from the neighboring tissues; and occasionally its function is interrupted by pressure, caused by proliferation of the connective tissue of the neurilemma. 184 NERVOUS THERAPEUTICS. Clinical Experience—Facial paralysis has yielded to Gelse- mium, Causticum, Aconite, Kali chlor., Kali iod., Mercurius, Bella- donna and Arnica. Therapeutic Indications.—Ge1semium.-Bruised pain be- hind and above the eyes; heaviness in the lids; impossible to close the eye or to raise the lid; paralysis of the facial muscles of the left side. Causticum.—Twitching of the lids and eyebrows, especially the left; sensation of heaviness in the upper lid, with inability to close the eye firmly; especially suited to cases caused by exposure to cold. Aconite.—Recent cases of a catarrhal or rheumatic origin; also when due to injury or to inflammation; anaesthesia of the affected muscles. Kali chlor.—Paralysis of the facial nerve, especially when affecting the muscles of the cheek ; pressure and tension in the face; cramplike drawing in the cheek; inability to puff out the checks or to blow with the mouth; especially adapted to idiopathic cases. ‘ A1'nica.—Facial paralysis due to injury, especially when there is much soreness of the affected parts; also when there are in- flammation and hyperaesthesia of the facial nerve. Kali iod.—Facial paralysis due to syphilitic disease in any of its forms. Mercurius.—This remedy is also indicated in syphilitic facial paralysis, whether caused by pressure of nodes, inflammatory exudations, neuritis or syphilitic disease of the brain. Belladonna.-—Acute cases, attended with inflammation of the nerve, redness of the face, hyperaesthesia, throbbing and ex- tension of inflammation from neighboring parts, as from the tonsils, parotid gland, etc. Compare, also, Ignatia, Graphites, Pulsatilla, Cocculus, Nux vom., Cadmium, Stramonium, Barium, Opium. Auxiliary Treatment.—Hammond, Butler and other elec- tricians highly recommend electricity in this disease, the former saying that the affection cannot be cured without it. One pole of the galvanic current should be placed opposite the stylo- mastoid foramen, and the other passed over each of the affected muscles in succession, every day. The weakened muscles may mrnrnnnrrrc PARALYSIS. 185 be supported, and the mouth drawn toward the centre of the face, by means of a double wire hook, curved at the ends and of the required length, one end of which should be placed in the angle of the mouth and the other over the ear of the affected side. ' DIPHTHERITIC PARALYSIS. Synonyms.—Postdiphtheritic Paralysis, Asthenic Paraly- sis; Fr., Paralysie Diphthéritique; Gen, Diphtheritische Ltihmung. ‘Definition. ——Paralysis associated with, or secondary to, diphtheria. Diagnosis.-—Although diphtheritic paralysis resembles that which is observed after other acute diseases, and also that which occurs in hysterical women, the simple fact that it was immediately preceded by an attack of diphtheria is sufficient to establish the diagnosis. Pathology. —The fact that the nervous centres are not always implicated has led to the conclusion that the paralysis is peripheral rather than central in its origin. The affection appears to extend from the peripheric extremities of the nerves toward the nerve-centres; hence, when the nerve-centres are involved their implication is probably secondary. Clinical Experience. — Gelsemium seldom fails to cure promptly all recent cases. Argentum is a good general remedy in these cases. Antimonium tart. acts promptly in patients suffering from oedema of the lungs. Causticum has cured cases of crossed paralysis following diphtheria, one arm and the opposite leg being affected; Arsenicum, where the paralysis was confined to the lower extremities; and Nua: vom., Lachesis, Cocculus, Arniea and Rhus tor. when limited to one side of the body. Therapeutic Indications.——See paralysis in general, pp. 54, 92. Auxiliary Treatment.—Most cases of diphtheritic paralysis will yield to the methodical use of electricity; indeed, it may be laid down as a rule that when the muscleswill respond to either the primary or secondary current recovery will speedily follow its application. When this is not the case the fault usually lies in the constitution, and we should endeavor, by 13 186 NERvoUs THERAPEUTICS. generous diet, fresh air, salt-water baths, exercise, etc., to revo- lutionize and build it up ; the paralysis will be found to grad- ually disappear as the health improves. GLOSSOPLEGIA. Syn0nyms.——Paralysis of the Hypoglossal Nerve, Paralysis of the Tongue; Fr., Paralysie de la Langue; Ger., Zungenldhmung. Definiti0n.—-Paralysis of the hypoglossal or motor nerve of the tongue. Diagn0sis.—As the hypoglossal nerve is the motor nerve, not only for the tongue, but for all the other muscles attached to the hyoid bone, with the exception of the stylo-hyoid, the mylo-hyoid and the middle constrictor of the larynx, we should, in estimating the character and position of the lesion, take into consideration the origin, course and distribution of the entire nerve. In disease of the nucleus of origin the pa- ralysis, which is commonly bilateral, is associated with pa- ralysis of the throat and lips, and there is usually more or less atrophy. If the disease is seated in the motor tract above the nucleus, that is, in the pons, crus or hemisphere, there is hemi- plegic weakness on the side corresponding to the paralysis of the tongue. When the disease is at the surface of the medulla the paralysis, which is commonly unilateral, is associated with paralysis of the corresponding half of the palate and vocal cord; and when thefibres of origin within the medulla are diseased, the paralysis of the tongue is associated with paralysis of the opposite limbs, so that the tongue deviates from the par- alyzed side. Path0l0g'y.——The disease is seldom, if ever, a primary affec- tion; hence the pathological condition is that of the associated disease or of the causal condition on which the paralysis de- pends. Clinical Experience.—As in all secondary affections, the treatment should be that of the causal disease. Where no specific disease can be assigned the‘ remedies which usually prove most beneficial are: Argentum, Causticum, Plumbum, Baryta carb., Opium, Nux mosch., Dulcamara, Stramonium, Bel- ladonna and Hyoscyamus. TORTICOLLIS. 187 Auxiliary Treatment.—-The occasional application of elec- tricity to the tongue is useful in some cases. The most con- venient way of applying it is by means of Tiirck’S tongue de- - pressor, the blade of which should be insulated, where it comes in contact with the lips, by a coating of sealing-wax. FACIAL SPASM. Syn0nyms‘.—Spasm of the Facial Muscles, Mimetic Spasm, Convulsive Tic; Fr., Spasme Faciale, Tic Oonvulsif; Ger, Ge- sichtshrampf. Definiti0n.——Tonic or clonic contractions of one or more of the muscles supplied by the facial nerve. Diagnosis.—A1l spasms of the facial muscles not consti- tuting a part of a wider convulsive movement, as in epilepsy, hysteria, etc., are to be regarded as facial spasms. Path0l0gy.—Some cases are purely functional, such as nictitation, or involuntary winking. Others are due to irritation of the trunk of the nerve by pressure of foreign growths, caries of the temporal bone, etc. But the majority are of reflex origin, and are due to cold, intestinal worms, etc. Treatment.-If possible, remove the cause; if not, consult indications under the head of convulsions. \ TORTICOLLIS. Syn0nyms.—Spasm of the Sterno-mastoid Muscle, Wry- neck; Fr., T orticolis ,' Ger, Steifer Hats, Halsstarre. Definition.——A tonic contraction of the sterno-cleido-mastoid muscle, producing a twisting of the neck to one side. Diagnosis.—It is scarcely possible to mistake the affection where there is no tumor or organic lesion to account for the deformity. Path010g'y.——Wry-neck is a true neurosis, due ‘in many cases to irritation of the spinal accessory nerve, conjoined with a want of proper antagonization, the latter resulting from fatigue or some similarly acting cause. Clinical Experience.——Aconite and Oimicifuga will promptly 188 NERVOUS THERAPEUTICS. cure the large majority of recent cases, especially those depend- ing on cold and exposure. Belladonna, Rhus to:c., Nucc vom., Dulcamara, Bryonia, Lachnanthcs, Cuprum and Mercurius some- times relieve in the early stages, but when fully developed medicine has very little power over it. Auxiliary Treatment.— Galvanization of the affected mus- cle and F aradization of the opposite one often give speedy relief in recent cases, but neither electricity, nerve-stretching nor any other procedure seems to materially benefit chronic cases. WRITER’S GRAMP. Synonyms. Scrivener’s Palsy, Anapeiratic Paralysis; Fr., Crampe des Ecrivains ; Ger., Schreibelcrampf. Definition.—A loss of power to perform certain muscular movements required in writing, telegraphing, instrument play- ing, etc., correctly, owing to a spasmodic action of the mus- cles concerned in the movements, due to their long-continued use in an unnatural and constrained position. Diagnosis.—The history of the case, aided by the location of the spasm, will in most cases render the diagnosis sufficiently clear. Pathology--As in facial paralysis, torticollis and other allied diseases, the paralysis proceeds from the periphery toward the centre, whence we infer that the disease is not central, but peripheral. What the molecular or anatomical changes in the affected parts, or in the nerves supplying them, are, is not known. Clinical Experience.-—But three or four remedies are known to have any marked curative power over this affection, namely, Gelsemium, Argentum, Strychnia, Arnica and Zincum. Recent cases will generally yield to the first of these remedies, provided the writer will give the affected muscles suflicient time to recover their lost tone, but not without; the other remedies mentioned are less certain. Auxiliary Treatment.—-Rest, galvanism and gymnastic exer- cise of the affected muscles constitute the most effective treat- ment in the majority of cases. Rest of the affected muscles, SPASM on THE GLOTTIS. 189 that is, rest from the particular muscular movements that have caused the trouble, is essential, whatever other treatment may be instituted. Dr. Poore’s plan of directing the continuous galvanic current down the muscles of the forearm, at the same time requiring the patient to continuously open and close his fingers, appears to give good results. The gymnastic treatment is similar, so far as the fingers are concerned, but the patient is required to execute three or four times a day a series of vigor- ous movements of the whole extremity while opening and closing the fingers. In this way the old habits are broken up, and the nutrition of the affected parts at the same time pro- moted. SPASM OF THE GLOTTIS. Synonyms.—-Spasm of the Larynx; Spasmodic Oroup, Laryngismus Stridulus; Fr., Spasme de la Glotte; Ger., Kahl- lcopfhrampf. Definition.—Spasmodic closure of the glottis, depending on tonic spasm of the adductor muscles of the larynx, producing a sudden arrest of inspiration, and ending in a shrill crowing sound as the inspiratory act is resumed and concluded. Diagnosis.--The disease may be distinguished from acute laryngitis, with which it is often confounded, by the absence of fever, the greater affection of the breathing, and by the absence of the croupy cough, which is the distinguishing symptom of the inflammatory affection. A foreign body in the larynx closely simulates spasm of the glottis, but the his- tory of the case will prevent any error of diagnosis. Pathology.—The disease is a pure neurosis, there being no anatomical change in the larynx. Excessive reflex irritability, arising from constitutional weakness or from some affection of the brain or medulla oblongata, is no doubt the chief factor in its production. Clinical Experience.—The most successful remedies for relieving the spasm are: Gelsemium, Sambucus, Belladonna, Chlorine, Corallium rub., Lobelia, Ipecacuanha and Kali brom. More or less benefit has also been derived from Moschus, Cup- rum, Arsenicum, Spongia, Iodine, Lachesis, Aconite, Nux vom., 190 NERvoUs THERAPEUTICS. Ignatia, Phosphorus, Carbo veg., Plumbum, Phytolacca and Bromine. Therapeutic Indications.-—Gelsemium.-Long, crowing in- spirations, followed by sudden and forcible expirations. This is perhaps the most reliable remedy we have for promptly relieving the spasms. Sambucus. — Inspirations less labored than expirations; awakes from sleep with symptoms of suffocation; face livid; gasps for breath; alternation of perspiration and dry heat; attacks usually occur between midnight and morning. Belladonna.——Red face; great arterial excitement; cerebral congestion; paroxysms occur during the day or evening; excited by drinking. Chlorine.—Crowing inspiration, expiration greatly impeded ; cyanotic and partially unconscious; chest inflated by a succes- sion of crowing inspirations to a painful extent. Iodium.-—Attacks provoked by enlarged cervical, bronchial and other glands; rachitic and scrofulous children; clayey stools; circulation feeble and easily disturbed by motion. Phytolacca.—Frequent spasmodic closure of the larynx; con- traction of the thumbs and toes; distortion of the face; eyes move independent of each other. Plumbum.-—Spasm of the glottis; asphyxia, with sudden arrest of breathing; mucus rattling in the throat. Cuprum.—Convulsive breathing, with cough ; blueness of the face and lips; cough relieved by swallowing cold water; when produced by fright. Ipecacuanha.——Blue face and cold extremities at the com- mencement of the attack; accumulation of mucus in the bronchia. Kali brom.—Often relieves night attacks, or when excited by the irritation of teething or of worms. Corallium rub.—Spasmodic closure of the larynx, with painful dyspnoea; face red, cheeks hot and feet cold. Auxiliary Treatment.—The warm bath, with cold water dashed on the head and face, usually puts an immediate end to the spasm; afterward cold sponging of the chest, with out- of-door exercise, tends to prevent its recurrence. Reflex cases FACIAL ATROPHY. 191 require the special treatment appropriate to each condition. Thus, if there is phimosis it should be immediately relieved by surgical operation ; if the child is teething the gums should be lanced; if the stomach is overloaded an emetic should be given; and if worms are present they should be dislodged, or the virminous irritation allayed, by appropriate treatment. FACIAL ATROPHY. Syn0nyms.——Neurotic Facial Atrophy, Unilateral Facial Atrophy, Progressive Facial Atrophy, Progressive Facial He- miatrophy; Fr., Atrophie Partielle de la Face, Aplasie Lamineuse Progressive, Trophonévrose Faciale; Ger., Prosopodysmorphia. Definition. —An affection in which one side of the face be- comes notably smaller than the other, owing to an atrophic condition of the cutaneous, subcutaneous and other tissues of the affected side. Diagn0sis.—Progressive facial atrophy may be readily dis- tinguished from progressive muscular atrophy, by the fact that, when the latter is seated in the face, it is not confined to that part, nor to one side of it, as in facial atrophy. In its early stages it is liable to be mistaken for facial paralysis, but the latter occurs suddenly, while facial atrophy is developed very gradually; moreover, the electro-excitability of the mus- cles is always diminished in facial paralysis, which is not the case in this disease. Path010gy.——Microscopical examinations of the affected muscles exhibit no degenerative changes of any kind, so that, so far as the muscles are concerned, there is simply atrophy without degeneration—a condition essentially different from what exists in other trophic diseases, such as atrophic spinal paralysis, progressive muscular atrophy, etc. From the fact that the upper and middle cervical ganglia have been found dis- tinctly tender on pressure made over them, Bastion and others attribute the disease to persistent irritation acting upon the cervical sympathetic; Hammond and others refer it to certain hypothetical “ trophic nerves;” while Vulpian, who positively affirms that it cannot be due to vaso-motor influences acting 1.92 NERVOUS THERAPEUTICS. on the parts which are the seat of the disease, regards it as an essential atrophy, due to some intracranial lesion. This opin- ion is based upon the fact that when the disease results from traumatic violence inflicted on the head or face its develop- ment is accompanied, in the great majority of cases, for several years, with pains of greater or less violence seated in the head, ordinarily toward the fronto-temporal region. Sometimes, also, there are spasmodic movements of the muscles of the face or of the jaws; and in some rare cases there has been numbness in the upper extremity of the opposite side. He, however, in common with all other authorities, is embarrassed to designate a seat for the lesion which can reasonably explain all the phenomena of the disease."< Clinical Experience.—-The only case of this disease that I have had an opportunity of treating, though never entirely cured, was seemingly arrested by Phosphoruse, continued over a period of nearly two years. The young lady finally married, and I lost sight of her. Therapeutic Treatment.—The remedies most likely to prove beneficial in this disease are the various preparations of Phosphorus, Belladonna, Calcarea, Argentum nit., Stramonium, Gclscmium, Baryta, Causticum and Sulphur. Auxiliary Treatment.—Bastion claims that marked ame- lioration has been produced, in some cases, by the long-con- tinued application of a continuous current of weak tension to the cervical sympathetic ganglia. PERIPHERAL ANJESTHESIA. Synonyms.——Neural, Cutaneous or Local Anaesthesia; Fr., Ancsthésic Cutanéc ; Ger , Anaesthesia, Anclsthcsie. Definition.-—Loss, more or less complete, of natural, and especially of tactile, sensibility. , Diagnosis.—Cerebral, spinal and cerebro-spinal anaesthesia —that is, anaesthesia of central origin——has already been con- sidered in connection with the several diseases on which it de- * See the author’s Intracranial Diseases, p. 153. PERIPHERAL ANZESTHESIA. 193 pends, while anaesthesia of the special senses does not come within the scope of this work. The chief point, therefore, in our diagnosis is to discriminate between peripheral anaesthesia, properly so called, and anaesthesia due to central causes. In cutaneous anaesthesia the existence of a peripheral cause will be suflicient evidence of the nature of the affection, while, on the other hand, anaesthesia of central origin is almost invari- ably associated with other marked symptoms of cerebral or spinal disease. In anaesthesia of the trigen1inus, or fifth pair of nerves, the elements of the diagnosis are given by Romberg as follows: “ 1. The more the anaesthesia is confined to single filaments of the trigeminus, the more peripheral the seat of the cause will be found to be. “2. If the loss of sensation affects a portion of the facial sur- face, together with the corresponding facial cavity, the disease may be assumed to involve the sensory fibres of the fifth pair before they separate to be distributed to their respective desti- nations; in other words, a main division must be affected be- fore or after its passage through the cranium. “ 3. When the entire sensory tract of the fifth nerve has lost its power, and there are at the same time derangements of the nutritive functions in the affected parts, the Gasserian gan- glion, or the nerve in its immediate vicinity, is the seat of the disease. “ 4. If the anaesthesia of the fifth nerve is complicated with disturbed functions of adjoining cerebral nerves, it may be as- sumed that the cause is seated at the base of the brain.” Pathology.--The pathology has been, for the most part, sufficiently indicated under the above heading. As cold ap- pears to be the principal cause of peripheral anaesthesia, it is highly probable, as pointed out by Rendu, that in the major- ity of cases neuritis lies at the bottom of the trouble. Therapeutic Treatment.—The most important point in the treatment is the removal of the cause. Until this is effected medi- cine can be of no permanent benefit, while afterward it is seldom required. When caused by external injuries, Arnica and Hypericum are indicated. Exposure to cold calls for Rhus 194 NERvoUs THERAPEUTICS; tox., Dulcamara, Causticum, Mercurius, Colchicum, Nux vom., etc., in prescribing which the accompanying symptoms and condi- tions should also be taken into account. Auxiliary Treatment.—Friction, massage and electricity are among the various means employed to restore the lost sen- sibility, the last of which is by far the most efficient. As a general rule, the secondary current is to be preferred, and this may be rendered still more effective by employing the wire brush, as one of the electrodes, upon the affected part. PART V. DISEASES OF THE SYMPATHETIC NERVOUS SYSTEM. HEMIGRANIA. Synonyms.—l\/Iegrim, Nervous Headache, Sick Headache, Cephalalgia Periodica; Fr., Migraine; G’er., Migrdne. Definition.-—A periodical headache, usually confined to one side or one half of the head, and frequently attended with more or less nausea and bilious vomiting. Diag'n0sis.——The periodicity of the headache, its unilateral form, and the gastric disturbances associated with it, sufficiently distinguish it from every other affection. Path0l0gy.—Formerly the disease was regarded as a pecu- liar form of neuralgia, dependent on gastric or hepatic de- rangement; but since Du Bois Raymond, who was himself a sufferer from it, made a careful study of the phenomena, it has generally been held to be due to an affection of the cervical portion of the sympathetic nerve, or of its centre in the medulla oblongata, giving rise to spasm of the cranial vessels and dis- turbances of the sensory nerves of the affected side of the head. Clinical Experience.—The remedies which have most fre- quently given relief to sick headache are: Sepia, Stannum, Belladonna, Sanguinaria, Iris vers., Arsenicum, Calcarea carb., Gelsemium, Pulsatilla, Veratrum, Spigelia, Kali bich., Bryonia, Oyclamen, Bromine, Niccolum sulph. and Natrum mur. The fol- lowing have benefited particular cases: Silicea, China, Nux vom., Ignatia,' Cafiein, Coflea, Carbolic ac., Aurum mur., Aconite, Cimici- fuga, Phosphorus, Ualcarea acet., Sticta, Zincum valer., Asafoetida and Sulphur. Therapeutic Ind.ications.—Sepia.—Boring, outward-press ing headache, or when caused by mental emotion, especially vexation, and attended with nausea, vomiting, shivering, pale (195) 196 NERvoUs THERAPEUTICS. face and flying heat; ameliorated by pressure, darkness and sleep; periodicity is a marked symptom, especially in females, to which this remedy is especially suited. Stannum.--One-sided headache in the morning, attended with nausea and ill humor; stupefying pain over the eye and in the temple, feeling as if the part would be crushed; pulsa- tive pain in the side of the head, with heat; face pale and sunken; retching and vomiting of bilious matter. Belladonna.——This remedy is specially indicated in attacks accompanied by congestion of the brain, heat and redness of the face, irritation of the sensory nerves of the eye and dilata- tion of the pupils; it acts best on the right side, and when the pain is aggravated by light, heat and motion, especially stooping. Sanguinaria.—-Hemicrania, which increases in violence with the sun’s ascent, decreases as it declines, and is preceded by scanty urine, passing off with a profuse flow of urine; also when the attacks occur periodically every week or at longer inter- vals; or when the attacks are most severe on the right side, and are followed by chills, nausea, vomiting of food or bile, and aggravated by the least movement, relieved only by sleep. Iris vers.--Attacks commencing with a blur before the eyes; dull, heavy, throbbing pains, with nausea, vomiting and great depression of spirits. Arsenicum.—-Hemicrania associated with bilious colic, bilious vomiting or some affection of the liver; great depression of spirits, thinks he will die; aggravated by cold; ameliorated by warmth; attacks renewed by going into the open air; great prostration; feels chilly and is very restless. Galcarea carb.-—-Hemicrania occurring in delicate or scrofulous constitutions, with irritable and obstinate dispositions, and attended with nausea and vomiting; aggravated, and fre- quently induced, by mental and bodily exertion, by exposure to the sun, or to cold and damp weather. Gelsemium.—Hemicrania accompanied by double vision or by dimness of sight, or with great sensitiveness to sounds; dull, heavy pains extending to the nape of the neck, with throbbing in the temples, and vertigo on rapid movement. HEMICRANIA. 197 Pulsatilla.—Semilateral headaches where the pupils are con- tracted, pulse quick, small and weak, or full and strong, with feeling of weakness, or else great strength; chilliness, followed by sweat, sometimes semilateral, nausea and vomiting, no thirst, alternations of flushing and paleness; worse before mid- night ; suited to delicate, chlorotic girls and to weakly females suffering from menstrual irregularities ; also to hemicrania in the male sex when attended with a feeling of intoxication. Veratrum alb.——Attacks attended with great anxiety, fear, coldness, small, rapid, intermitting or slow pulse, nausea and sometimes vomiting; occasionally attended by a sensation of both warmth and coldness on the scalp and sensitiveness of the hairs ; cold sweats on the forehead, weakness, faintness and profuse micturition ; attacks usually nocturnal. Spigelia.—Periodical attacks, generally confined to the right temple or to the left eye and left temple, pulsating, darting or boring, increasing and declining with the sun, and accom- panied with paleness of the face, nausea and vomiting; aggra- vated by motion, stooping, noise, thinking or mental emotion. Kali bich.-—Hemicrania commencing at the internal angle of the eye, and gradually spreading over the brow and side of the head, usually the left ; in many cases there is dimness of vision, with aversion to light and noise; pains are usually of a shooting character, extending from the root of the nose to the external angle of the eye; in other cases the pain is dull, heavy and throbbing, and confined to small spots on the side of the head. Bry0nia.—Deep stitching or throbbing pains in the left side of the head, with pressure from behind forward, accompanied by nausea and vomiting; soreness of the scalp and throbbing over the whole side of the head; aggravation from rising, stooping or sitting down. Cyclamen.——Violent left-sided headache, with heat and throb- bing, glittering before the eyes, dimness of vision, chilliness, with nausea; aggravated by motion, especially stooping; worse in the afternoon and evening. Bromine.—Hemicrania of the left side of the head, usually of but little use on the right side; throbbing in the forehead and 198 NERvoUs THERAPEUTICS. temple; pains in the eye, eyelid and eyebrow of the affected side. Niccolum sulph.—Periodical attacks accompanied by a sense of great fulness, heat and stupefaction, setting in on.rising and increasing until noon, with vertigo and nausea; distress so great as to make the patient groan in anguish. Natrum mur.—Hemicrania occurring in scrofulous or scor- butic constitutions; attacks periodical and attended with marked weakness, prostration, thirst, palpitation and nausea; pains increase and decrease with the course of the sun. Auxiliary Treatment.—Absolute rest, low diet and exclu- sion from light and noise are efficient means of mitigating the distress. The inhalation of three or four drops of Amyl. nit. every fifteen or twenty minutes frequently gives speedy relief. Morphia, Sulfonal, Antipyrine and Phenacetine, in sensible doses, are sometimes given as palliatives, especially in obstinate cases. The constant current of electricity has often proved beneficial, but is far from being a specific. Care should be taken not to make the current too strong, for fear of causing amaurosis. EXOPHTHALMIC GOITRE. Syn0nyms.—Exophthalmic Bronchocele, Graves’ Disease, Basedow’s Disease; Fr., Maladie de Graves, Goitre Exophthal- migue; Ger., Basedow’sche Krankheit, Glotzaugenkropf. Definition.—A nervous affection, characterized by certain functional disturbances of the circulation, and giving rise to violent palpitations of the heart, bronchocele and exoph- thalmos. Diagnosis.—The. disease is of such a peculiar character as to render an error in diagnosis impossible. PathOl0gy.—The true nature of the disease, and the rela- tion which the cardiac affection sustains to the bronchocele and exophthalmos, are involved in much obscurity and doubt. The most rational and generally received theory is that which refers the disease to functional disturbances of the sympathetic nervous system. Not only do the general symptoms point to disturbances of the vaso-motor centres, but the almost number- MYX(EDEMA. . 199 less complications of the disease, many of which are of an ex- tremely variable and transient character, appear strongly to confirm this view of its nature. Clinical Experience.-—Iodium and its various preparations, Spongia and Bromine, have eflected most of the cures which have been recorded, though Lycopus, Badiaga, Cactus, Ferrum, Calcarea carb., Belladonna, Baryta carb., Secale cor. and Natrum mur. have occasionally been attended with success. The same is true of Amyl nit., which is administered by olfaction. One of my cases, after resisting all other remedies, yielded perma- nently to Bromine 3°. Therapeutic Indicati0nS.—Although the disease is rich in symptoms, they are too variable to be studied outside the ma- teria medica. In addition to the remedies above mentioned, compare Phosphorus, China, Silicea, Digitalis, Platina, Sepia, Cimicijfuga, Silicea, Gelsemium and Sulphur. Auxiliary Treatment.-——Galvanism, applied to the sympa- thetic nerve, has been employed with success in many cases, especially in curing the goitre and exophthalmus, and also in improving the general health; it is also highly useful in regu- lating the menstrual function, upon the disturbance of which many cases measurably depend. Whatever tends to invigo- rate the system and improve the general health usually exerts a beneficial influence upon the disease. The patient should therefore abstain from the use of stimulants, take regular but gentle exercise in the open air, make use of a plain, but liberal, nutritious and easily digestible diet, and avoid all emotional or other excitement. MYX(EDEMA. Synonyms,—The Mucoid Disease, Ord’s Cretinoid Affec- tion, Mucoid Cretinism; Fr., Myxédéme; Ger., Myxddeme. Definition.—A disease in which the tissues of the body are progressively invaded by a mucoid, jelly-like substance, un- accompanied by albuminuria or other sign of kidney disease. Diagnosis.-—The disease is not likely to be confounded with anasarca, which it most resembles, as the oedema does not pit 200 msnvous THERAPEUTICS. upon pressure, but, on the contrary, is resilient like India rubber. In scleroderma the surface is hard, there is no per- manent reduction of temperature, as there is in myxoedema, and the disease belongs to a much earlier period of life. The clubbing of the fingers, as well as the mental symptoms and the history of the case, will also serve to distinguish it from arsenical or other forms of swelling. Pathology.-The mucoid deposit is found in almost every part of the body, both at the surface and in all the great nerve- centres. The nervous elements undergo yellow degeneration or are atrophied, the nerve-fibres are more or less wasted, and the small spaces filled with hyaline material. The identity of the pathological process in the nerve-centres and in the other tissues appears to show that they are not related as cause and effect, but form parts of some general disturbance of nutrition. Clinical Experience.— Glonoin, Arscnicum, Jaborandi and Calcarca carb. are the only remedies that have so far appeared to materially benefit these cases. Auxiliary Treatment.-—Dr. Ord says that he has in two cases found benefit from the use of vapor baths. Friction has also seemed to benefit some cases. ANGINA PECTORIS. Synonyms.—Breast-pang, Cardiac Neuralgia, Neuralgia of the Phrenic Nerve, Hyperaesthesia Plexus Cardica, Sterno- cardia, Sternodynia, Sternalgia, Syncope Anginosa: Fr., An- gine dc Poitrinc; Ger, Brustbrdune. Definition.-—A nervous affection, often complicated with organic disease of the heart, characterized by severe paroxysms of pain and sense of constriction, commencing in the region of the sternum or deep in the chest, and extending over the left side of the thorax and the left arm, more rarely over both sides and arms; the pain is often associated with faintness and anxiety, and with various other senso-motor and vaso- motor disturbances. Diagnosis.—The diagnosis may be easily made from the characteristic symptoms, as given in the above definition,viz.: ANGINA PECTORIS. 201 great pain, occurring in paroxysms, in the region of the heart, accompanied by a sense, rather than fear, of sudden death, by the feeling of faintness, constriction and cardiac oppression, by the radiation of the pains, etc. The differential diagnosis between stenocardia, properly so called, and other forms of angina pectoris is as follows: Angina Vera. A6 Angina Spuria. Most frequent at the age of laterio- sclerosis, after forty and fifty years. More frequent in males. Attack provoked by every act necessi- tating an effort; spontaneous at- tacks are rare. Rarely periodical or nocturnal. ‘The attack isolated from any other symptom. The vaso-motor form rare. Anguish, with sensation of compression and as in a vise. Severe substernal pain. Pain of short duration (2 to 15 min- utes), ceasing after the effort. Attitude, silence, absolute immobility necessary to stop the pain. Coronary scleroses (of the arteries) the cause. _ Arterial medication. At every age, even during childhood. More in women. Attacks from efforts rare; the most attacks come on spontaneously. Mostly periodical, even at the same hour, and nocturnal. Neurotic symptoms frequent. Vaso-motor form frequent. Sensation of distension of the heart, with painful anguish. The pain more in cardiac region. Pain lasting one or two hours and not ceasing with the eflbrt. Incessant agitation, walks about, rest does not stop the pain. N euralgia of the nerves and of the cardiac plexus. Anti-nervous and anti-neuralgia medi- cation. Pathology.—We see no reason for changing the views we have elsewhere expressed on this subject. Notwithstanding the fact that organic lesions of the heart are almost always associated with angina pectoris, the symptoms are such as to require it to be placed among the neuroses, and such is now the usual classification. Flint, Anstie, Laennec, Eulenberg, Trousseau and others substantially agree in regarding the disease as essentially a neuralgia, while Bomberg, Friedrich, Klapka and others believe it to be a hyperaesthesia of the cardiac plexus. The author is of the opinion that the spinal 14 202 NERvoUs THERAPEUTICS. system of nerves is primarily, and the sympathetic system secondarily, involved in these cases, and that the spasm is a reflex symptom, generally of peripheral, but sometimes of central origin. The sources of peripheral irritation are found in suppressed neuralgias, in the various organic lesions of the heart, and in bronchial, pulmonary and abdominal conges- tions; the central are chiefly, if not wholly, confined to the various forms of spinal irritation.* Clinical Experience.—-While Amyl nit. usually gives the most rapid and certain relief during the paroxysm, the most successful curative agent is Iodium and its various compounds, especially Kali iod. and Natrum iod. Spongia, Cactus, Arsenicum, Glonoin, Spigelia, Aconite, Cuprum, Laurocerasus, Veratrum alb., Aurum mur., Agaricus and Lachesis have given relief in special cases, agreeably to the following Therapeutic Indications. ——Iodium.--Cramping pressure in the region of the heart; spasmodic palpitation of the heart; sensation as if the heart was being squeezed together; pale face; great oppression of the chest, with inclination to faint; anguish, physical and mental, with anxiety. Natrum i0d.—Organic complications, with frequent attacks of angina; oppressive anguish in the region of the heart, with fear of sudden death; aching pain in the region of the heart, with sense of constriction; anxious feeling, as if something dreadful was about to happen; mind and body greatly depressed. Kali iod.—Violent pain in the middle of the chest, extending to the shoulder; extremely violent stitches deep in the chest; pain in the chest as if out to pieces; irresistible desire to go into the open air; torturing feeling of anguish, with oppression of breathing and loss of voice. Spongia.——Cramping pain in the heart, with great anguish in the chest; extreme oppression of breathing, with feeling of suffoca- tion; sudden pain and pressure within the chest, with anxiety; face pale; nausea; lower part of the body feels numb, upper part sore and bruised. Amyl nit.——-Great cardiac oppression and tumultuous action 0 * Hart’s Diseases of the Nervous System, p. 273. ANGINA PECTORIS. 203 of the heart; aching pain and constriction around the heart, with precordial anxiety; visible pulsations of the carotid arteries; very severe pain in the region of the heart, extending to the right arm; angina pectoris, with great agony; anxiety as if some- thing might happen, must have fresh air. Natrum nit.—Oppressive anguish in the chest, with dyspnoea; aching pain in the region of the heart; cardiac palpitations, with anguish; moderately severe cases of angina pectoris. Cactus grand.—Oontinuous palpitation of the heart, both day and night; worse when walking, at night, and when lying on the left side; sensation as if the heart was grasped by an iron. hand, preventing movement; angina pectoris, with organic com- plications. Arsenicum.—-Great mental and bodily anguish from severe pains in the region of the heart, extending down the arm; great dyspnoea and prostration; surface and extremities cold; attacks followed by numbness and prostration; periodical attacks, attended by faintness and extreme weakness; worse after midnight and from motion. Glon0in.——Syncopal form, with pale face, disposition to faint, nausea and extreme anguish of mind and body; crampy pains in the region of the heart, producing a feeling of faintness and sense of impending danger; attacks followed by extreme and pro- longed prostration. Spigelia.—Palpitation of the heart, with anxious oppression of the chest; painful constriction in the left side of the chest, arresting the breathing and producing an anxious feeling of suffocation; pains increased by leaning forward and by motion. Ac0nite.—Constant pressure in the left side of the chest, with dyspnoea, increased by exercise; aching, constrictive pain in the left side of the chest, with paroxysms of great anguish and fear of death; heat and flushing of the face; attacks occurring .in young, strong, plethoric subjects. Cuprum.—Sudden attacks, attended by intense dyspnoea, faint- ness and slight convulsions; surface cold and blue; old chronic cases, in feeble subjects, with slow pulse and but little vitality. Laur0cerasus.—Violent attacks, attended by extreme suffering, suflocative gasping for breath and loss of speech; surface cold and moist; recent cases, without serious organic complications. 204 mrnvous THERAPEUTICS. Veratrum alb.—Functional cases, attended by excessive an- guish, arresting the breathing, and producing a feeling of im- pending suffocation; painful constriction of the chest, with Violent palpitations and cutting pains. Agaricus mus.——-Cardiac pain and dyspnoea, increased by walking, with continued pressure at the pit of the stomach; great precordial anguish, with paralytic pain in the left arm, neck and nape of the neck; frequent empty cructations. Aurum mur.-—Palpitation of the heart produced by wallcin g in the open air, and increased by continuing to walk, until the anguish becomes so extreme as to compel the patient to desist from all exercise in the open air, though such patients can walk for hours in a close room without inconvenience (Kafka). Lachesis-—Sternal pressure and dyspnoea extending to the shoulders, and feeling as if the thorax was held by an iron band ; patient is pale, weak and trembling with anguish; pulse small, irregular and intermitting; surface covered with cold sweat; tendency to faint; aggravated by motion. Compare, also, Naja trip., Gelscmium, Crotalus, Digitalis, Lyce- podium, Cimicifuga, Dioscorea, Angustura, Moschus, T abacum, Oxalic ac., Bryonia, Juglans, Asafwtida, Rhus to:c., Tarantula, Lactuca vir., Arnica, Phytolacca and Sepia. Auxiliary Treatment.--Any very strong, stimulating or revulsive impression made upon or over the heart during the occurrence of a paroxysm will usually put an immediate or speedy stop to it. Hence we find that electricity, both the in- duced and constant currents, as well as the spraying of ether or the application of hot bran poultices over the heart, will generally give relief. Many a victim of angina pectoris now finds instantaneous relief by carrying with him for immediate use a small vial filled with cotton moistened with a few drops of Amyl nit., which he can inhale whenever threatened with a new attack. GASTRALGIA. Synonyms.—Neuralgia of the Stomach, Heartburn, Gastro- dynia, Cardialgia Nervosa; Fr., Gastralgie; Gen, Magenschmerz. Definition —A gastric neurosis, characterized by pain, GASTRALGIA. 205 often severe, in or about the stomach, and, as a rule, uncon- nected with any other affection of the part. Diagnosis.——Gastralgia may be distinguished from acute gastritis by the absence of the fever, the persistent vomiting, the sensitiveness to hard pressure, and other symptoms belong- ing only to the inflammatory affection. Cancer of the stomach may be known by the progressive emaciation and steady char- acter of the pain which accompanies it. In perforating ulcer of the stomach the painfulness and sensitiveness to pressure are confined to a small spot, being limited to the seat of the ulcer. Dyspepsia, and the passage of biliary calculi, may also be distinguished by the symptoms peculiar to each. Pathology.——-Nothing is positively known concerning the pathology of this affection. The symptoms plainly point to functional disturbances in both the spinal and sympathetic systems of nerves, in the production of which malnutrition no doubt constitutes the chief etiological factor. Debility pro- duces nervous excitability, and gives rise to a great variety of ' functional disturbances, as we see in hysteria, spinal irritation, anaemia, etc.—conditions frequently associated with gastralgia, as they are with each other. It is reasonable to infer, there- fore, that they all have a common basis in malnutrition of the nervous centres, though no organic changes sufficient to account for the phenomena are discoverable. Clinical Experience.-—Nux vom., Ignatia, Arsenicum, Ozcalic ac., Argentum nit., Bryonia, Carbo veg. and Pulsatilla stand at the head of the list as curative agents in this disease, though cures have also been effected by Belladonna, Ferrum, China, Petroleum, Stannum, Plumbum, Bismuthum, Colocynth, Cocculus, Lachesis, Hydrastis, Dioscorea, Veratrum, Aurum mur., Sulphuric ac., Iris ver., Hydrocyanic ac., Ptelea, Cina, Rumex, Sepia, Calcarea carb., Nitric ac., Lobelia, Phosphoric ac. and many other remedies. Therapeutic Indications.-—Nux V0n1.—Clawing, drawing and cramping pains in the stomach, with tension and pressure between the shoulder-blades ; the pain extends into the chest, or downward into the abdomen; epigastrium sensitive to the touch; pain worse from light pressure and better from hard pressure; gastralgia brought on by high living, indulgence in tobacco-chewing and smoking, sedentary habits and habitual 206 NERvoUs THERAPEUTICS. constipation; pain worse from eating; pressure in the epigas- trium after meals, as from a stone, from indigestion; heart- burn. This remedy alone will, if persevered in, cure the ma- jority of cases. Ignatia.—Cramping pains in the stomach; sharp, pinching, pressive pains in the pit of the stomach and in the right hypo- chondrium ; pressive pain in the epigastrium; a relaxed, flabby feeling in the stomach, or an all-gone feeling, as if from fasting, with great exhaustion; hysterical, changeful moods, now tearful, silent and melancholy, then impatient, irresolute, ill- humored and angry; burning in the stomach; regurgitation of food; frequent voiding of large quantities of pale urine; especially suited to hysterical and nervous persons, especially females and those addicted to the excessive use of tobacco. Arsenicum.—-Acute burning, or ‘gnawing, corroding pains, accompanied by great restlessness, nervous excitability, cold- ness of the extremities, palpitation of the heart and nightly aggravations ; feeling as if the stomach was inflamed ; pressure in the stomach as from a lump; vomiting of food as soon as taken; faint, sickly feeling, with pale face and earthy com- plexion; induced by eating ice cream, cake, etc.; relieved by drinking milk. Argentum nit.-—Severe gastralgia, attended with heartburn, which is aggravated or excited by eating; feeling as if a stone lay in the stomach; gnawing, ulcerative, sore pain, seated at one spot, or radiating to different parts, with spinal irritation; pains sometimes appear to depend upon an irritable state of the nerves of the stomach proper; often there are flatulence, nausea and palpitation ; pain increases and decreases gradually ; hard pressure in the pit of the stomach sometimes relieves. Bryonia.——Contractive, pinching pains, relieved by eructa- tions ; pressure in the stomach after eating as from a stone; soreness and tenderness in the epigastrium ; bloated feeling in the stomach, with stitches and oppression of breathing; symp- toms aggravated by motion and by eating; pains come on in chronic cases an hour or two after eating and continue for several hours. Garbo veg.—Gastralgia, with waterbrash, coming on about 3 P.M., with thirst for cold water; bloating of the stomach, GASTRALGIA. 207 with burning pains, relieved by eructation; vomiting of large quantities of mucus tinged with bile, giving relief; suited to cases complicated with hysteria or dyspepsia, especially if there is present a hyperaemic and irritable condition of the lining membrane of the stomach. Pulsatilla.—Heartburn when the stomach is empty; sour and bitter vomiting, with absence of thirst; feeling as if food had lodged in the oesophagus; indigestion provoked or aggravated by eating rich or fat food. Bellad0nna.——Cramping or shooting pains in the pit of the stomach, forcing the patient to bend backward and to hold his breath; periodical pains in the pit of the stomach, with tremor; region of the stomach sensitive to the touch; face bloated and congested; pressing, drawing and clutching pains extending to the back, with nausea, thirst and vomiting, ag- gravated by drinking water or by motion, and ameliorated by eating. 0hina.—Gastralgia, attended with great chilliness or coldness, constant feeling of weariness and debility, heartburn, with sour eructations, bloated abdomen and palpitation of the heart; gastralgia at a certain hour every day or every other day; gastralgia after natural or artificial depletions; torpid liver, with jaundiced hue, and large, undigested stools, worse at night; pains aggravated or excited by cold, by eating, by fatigue or by mental emotions. Oxalic ac.—Gastralgia appearing after eating, with pyrosis and cold feeling externally between epigastrium and umbilicus. Veratrum.-—Pain in the epigastrium, coming on gradually, radiating upward to both sides and to the back between the scapulae, increasing in violence till it becomes agonizing, then gradually wearing off; especially adapted to those cases in which the coeliac plexus and sympathetic are involved; pain increases and subsides gradually, and is attended with marked coldness of the extremities. 00cculus.—Cramping pains in the stomach, preventing sleep; violent pinching, griping and cramping pains in the epigas- tric region; great distension of the stomach from an accumu- lation of gases; especially suited to cases where Nux vom. being indicated fails to cure, and pyrosis is not present. 208 ' NERVOUS amrnnarnurrcs. Colocynth.-—Pains paroxysmal and extend into the umbilical region, obliging the patient to bend double; exacerbations re- cur every few minutes, are not the result of indigestion, but rather, in some cases, of emotional excitement. Ferrum.—Anaemic cases, with atony of the stomach; heart- burn, with feeling of a load in the stomach; vomiting imme- diately after eating, which usually relieves the suffering; aggra- vated or induced by coughing and moving about. Bisml1thum.—Pressure in the stomach as from a load; burn- ing pain in the stomach, extending to the spine, with water- brash, flatulence and extreme prostration; pains are sometimes relieved by bending backward. This is the principal remedy of old-school physicians. Stannum.—Heartburn, canine hunger, sinking at the pit of the stomach, great uneasiness; patient finds relief by walk- ing; the pain comes on gradually, extends to the navel, is re- lieved by pressure and is very obstinate. Consult, also, the other remedies above mentioned, likewise the therapeutic indications given under the head of cnteralgia, p. 212. Auxiliary Treatment.—Electricity, sinapisms and fomen- tations over the stomach, and similar measures, may be of some value during the paroxysms, but careful attention to diet and the methodical usg of the shower-bath, galvanism, etc., during the intervals between the attacks, will, by strengthen- ing the system, be of much greater benefit in most cases, espe- cially in weakly, neurotic, hysterical subjects. OVARALGIA. Synonyms.—Pain in the Ovaries, Ovarian Neuralgia, Ova- rian Irritation; Fr., Névralgie des Cvaircs; Gcr., Neuralgie der Ovarien, Neuralgie der Eierstbclce. Definition.-A nervous affection of the ovaries, character- ized by pain of a neuralgic character, occurring in paroxysms and unattended with inflammation or, necessarily, with en- largement. Di‘agnosis.——The pain of ovaralgia is characteristic, being OVARALGIA. 209 neither burning, as in ovaritis, nor pinching, as in colic, but sets in suddenly, is attended with distinct remissions, and is relieved by pressure; sometimes, also, it shifts to other parts, showing clearly its neuralgic character. Pathology. — Ovarian hyperaemia, resulting from the monthly ripening and discharge of the ovum, is the only known condition, aside from the neurotic constitution common to neuralgic subjects, capable of producing the disease. Neither of these conditions, however, are necessary factors in its causa- tion, though their combination is a fruitful source of the pain, as testified to by many women who never complain of it at any other period. The rheumatic diathesis also fagors it, as it does other forms of neuralgia. These conditions are calcu- lated to render the ovaries sensitive to influences which would otherwise make no painful impression upon them. Clinical Experience.—Ignatia is a reliable remedy in cases occurring in hysterical subjects, especially when the pain is sharp and irritating, with abundant flow of colorless urine, or when the neuralgia is caused by grief; Conium, when, with the ovaralgia, there are sharp twinges of pain in the mammae; Lilium tig., when the ovary feels as if squeezed in a vise; Naja, obscure ovarian pains; Ammonium brom., when the pain is a dull, heavy, persistent ache, and is aggravated by excitement; Cimiczfuga, patients of a rheumatic diathesis, or who are sub- ject to menstrual colic and dysmenorrhoea; Ferrum et Strychnia, anaemic women, in whom the menstrual flow ‘is scanty and the mucous membranes pale; Zincum val., in cases of pure neurosis, pain shoots down the limb even to the foot, also in chronic cases; Chininum ars. or Chininum sulph., when inter- mittent or of malarial origin ; Gelsemium, when the pains seem to radiate from the spine, or when there is pain in the back of the head and neck; Apis, sharp, cutting pains in the left ovary, or contractive, spasmodic pains in the right ovary; compare, also, Caulophyllum, Hamamelis and Colocynth. Auxiliary Treatment.—Dr. Julia Holmes Smith recom- mends the application of hot sand, well saturated with sea- water, over the affected ovary; also its exposure, and that of the surrounding parts, to the direct rays of the sun for an hour every day, aflirming that the heat and vivifying power of the 210 NERvoUs THERAPEUTICS. sun’s rays make it a valuable curative agent not sufficiently appreciated by the profession. I can fully confirm this testi- mony, having witnessed several remarkable recoveries by this process while in California, where the sun-bath is generally appreciated by all classes. HYSTERALGIA. Synonyms.—-Neuralgia of the Womb, Uterine Neuralgia, Irritable Uterus, Uterine Colic; Fr., Fortraiture; Ger., Neuralgie der Gebéirmutter. Definition.-—Neuralgic pains in the uterus, sometimes ex- tending through the pelvis, not connected with any demon- strable morbid alterations in that organ. Diag‘n0SiS.——The history of the case, the character of the pain, the absence of inflammation, the periodicity of the attack, the locality of the suffering, and the fact that the pain is usually relieved by pressure, when all are combined in the same case, are sufficient not only to establish its neuralgic character, but to distinguish it from every other painful affection of the part. Patho1ogy.——What is said under this heading in the previ- ous article applies with equal force to hysteralgia. There is no doubt that some forms of dysmenorrhoea belong to this cate- gory. Indeed, most of those uterine pains which occur between and remote from the menstrual periods are usually due to some other disorder of the sexual organs, and are seldom cases of pure primary neuralgia. Clinical Experience.—Cimicifuga is one of our most reli- able remedies for uterine neuralgia, especially when it is of rheumatic origin; Belladonna has long been a favorite remedy for irritable uterus, especially when the pains are sharp, lan- cinating and throbbing, and are aggravated by exercise; Arsenicum is a valuable remedy if the pains are of a burning character and attended by chilliness, hot, dry skin, thirst, rest- lessness and anguish; Calcarea, if the patient has flying pains about the pelvis, perspires easily and is poorly nourished; Gelsemium, if the patient is hypochondrical, fidgety and com- plains of vertigo; Sepia, if the pains occur at the climacteric period; Caulophyllum and Rhus rad., if there is any rheumatic ENTERALGIA. 211 tendency. Compare, also, Platinum, Xanthoxylum, Ignatia, Pul- satilla, Nux vom., Veratrum, Zincum val., Coflea, Strychnia, Conium, Helonias, Aconite, Sabina, Bryonia, Sulphur and others. Auxiliary Treatment. -—The constant current, applied with an insulator through the vagina, hot vaginal injections, ' hot compresses and similar measures often afford considerable relief. Hygienic treatment as in other forms of neuralgia, which see. ENTERALGIA. Syn0nyms.——Neuralgia of the Bowels, Enterodynia, Neu- ralgia Mesenterica, Neuralgia Meseraica; Fr., Névralgie Intesti- nale; G’er., Neuralgie der Eingeweide, Darmweh. Definiti0n.——-An affection of the nerves of the intestines, characterized by paroxysms of sharp, intense pain, without in- flammation or any discoverable organic lesion. Diagnosis.—-The disease is very apt to be confounded with colic; indeed, many authors regard enteralgia and intestinal colic as essentially one and the same disease. The chief difference between the two affections lies in the fact that enteralgia is a true neuralgia, while colic is dependent on spasm of the muscular walls of the intestines. In the former the pains are darting or lancinating, in the latter twisting or griping. An error in this particular is, however, of but little consequence, since the treatment is essentially the same in both. Enteritis and other inflammatory affections may be known by the presence of inflammatory symptoms, such as fever, thirst, tenderness on pressure and the stationary char- acter of the pain, none of which symptoms belong to enteralgia. Pathology.-—Impaired vitality of the nerve-centres, whether resulting from hereditary weakness, anaemia, malaria, plum- bism, or any form of blood deterioration, lies at the foundation of neuralgia, and enteralgia is no exception to the rule. What the exact relation between them is, other than that of cause and effect, is simply a matter of pure speculation; but, consider- ing the nature of these etiological factors, it is reasonable to infer, as already pointed out, that the disease is dependent on mal- nutrition of the nerve-centres, and this view is confirmed by the apparently central origin of the affection. 212 nnnvous THERAPEUTICS. Clinical Experience. ——- Enteralgia resembling colic, or when arising from indigestion, usually yields to Nua: vom., Pul- satilla, Dioscorea, Colocynth, Arsenicum or Chamomilla; lead colic, or enteralgia resembling it, Alumen, Alumina, Platina, Opium, Podophyllum; abdominal hyperaesthesia, Plumbum, Cuprum, Zincum, Stannum. ~ - Therapeutic Indications.—Nux vom.—Neuralgia of the bowels from indigestion or overeating; attacks resulting from dissipation or from sedentary habits; periodical attacks occurring after eating or after regular meals; pains relieved by bending double or by lying on the face; constipation; diurnal drowsi- ness. . Arsenicum.——Attacks coming on suddenly after eating and drinking, especially after partaking of ice water, cake or ice cream; periodical attacks due to malarial influence; neuralgic attacks followed by great prostration, the strength suddenly sinking; burning, cutting pains, attended by great restlessness and intolerable sufl’ering; paroxysms attended by nausea and vomiting, or with thin, watery stools; pains worse at night, also after eating and drinking, better from warm applications. Colocynth.——Pains appear to radiate from the umbilicus, are of a sharp, cutting, darting or twisting character, and occur in paroxysms; relieved by bending double or by hard pressure ; coffee and smoking relieve, but food and other kinds of drink usually aggravate. Dioscorea.——Severe colic-like pains, which do not intermit and are aggravated by rest; relieved by stretching the body out or by walking about; hypcrwsthesia of the abdominal nerves; pains shift their location suddenly and appear in distant parts, as the fingers and toes; stools bilious and offensive. Ghamomilla.—Colic-like pains in the region of the navel, also lower down on both sides, with pain in the hollow of the back as if broken; abdomen swollen and drumlike; flatus passed in small quantities without relief; relieved by warm applications. Podophylll1m.—Lead colic ; frequently recurring attacks, ac- companied by retraction of the abdominal walls; severe straining during stool, with escape of flatus; morning aggravations; attacks renewed by eating and drinking. ENTERALGIA. 213 Alumina.——Lead colic ; paroxysmal pains, with dyspnoea, worse when stooping; violent cutting pains, principally in the evening, succeeded by oppression of the chest; colic-like pain, followed by diarrhoea and pain in the region of the kidneys; pinching and lacerating pain, with chilliness in the abdomen, relieved by heat. 0pium.—Lead colic; violent cutting pains in the abdomen, as if made with a knife; constipation, with hard and distended abdomen; pains worse before and after stool; hypochondria painful when touched. Plumbum.—Excruciating pains in the umbilical region, shoot- ing to other parts, and moderated by pressure; recti muscles hard and knotty; abdomen retracted to the utmost extent; ameliorated by hard pressure and by friction; obstinate con- stipation; pains resembling lead colic, but due to some other cause. Cuprum.——Violent cutting, drawing, intermittent pains; ab- domen retracted and sore to the touch ; pains cause the patient to utter fearful screams; very restless and uneasy, constantly tossing about; worse by drinking cold water. Platina.—Lead colic ; severe colic-like pains, with sensation of burning and writhing around the abdomen, with oppressed breathing, and with a tremulous sensation through the whole body; drawing pains, extending from the chest to the groins and into the genital organs; patient screams and tosses about in every direction to relieve his suffering. Bellad0nna.—Violent cutting, clutching, clawing pains in various parts of the abdomen, constantly shifting about, ap- pearing and disappearing suddenly; light pressure aggravates, but hard pressure relieves; thirsty, but drinks little, as drink- ing aggravates the pains; tendency to cerebral hyperaemia; worse until evening and after midnight. Compare, also, Ignatia, Cocculus, Mercurius, Aconite, Phos- phorus, Rhus tox., Veratrum, Iris vers. and Sepia. Auxiliary Treatment.—-Hot fomentations, warm or hot water enemas, frequently repeated, mustard foot-baths, hot Aconite and Chloroform liniments often give great relief. In lead colic it is sometimes necessary to resort to Morphia, which is best given hypodermically. PART VI. SYMPTOMATIC DISEASES. CEPHALALGIA. Syn0nyms.—Headache; Fr., Cephalalgie, Douleur de T éte, llfal a Téte; Ger., Kopfschmerz. Definition.—Pain in the head, usually symptomatic of some other affection. ' Diagnosis.—Hemicrania is the only affection liable to be confounded with it. In hemicrania the pain is more or less unilateral, is frequently associated with nausea and bilious vomiting, is generally ushered in by premonitory symptoms, and is usually of a periodical character—-—peculiarities which do not characterize ordinary headache. Path0log'y.——Excluding hemicrania as a separate disease, headaches, though embracing numerous forms or varieties, may be conveniently arranged in three separate classes, namely: (1) structural headaches, or those depending upon disease within the cranium; (2) congestive headaches, which may be either active or passive; and (8) toxaemia headaches, which include not only those of a rheumatic, syphilitic and other dyscracic char- acter, but all those which attend fevers and inflammatory affections, some of which are also partly congestive. This classification is of itself sufliciently descriptive of their nature, Clinical Experience.—C0ngestive headaches generally yield to Belladonna, Aconite, Ammonium carb., China, Cactus, Glonoin, Ferrum, Asclepias syr., Pulsatilla, Digitalis, Cimicifuga, Carbo veg., Calcarea carb., Alumina, Atropine, Amyl nit., Chamomilla, Bryonia, Camphor, Cocculus, G-ratia, Fluoricum ac., Causticum, Caladium, Arnica, Agaricus, Capsicum and Gelsemium; or else to Kali carb., Lycopodium, Mercurius cor., Lachesis, Hamamelis, Magnesia carb., Silicea, Theridium, Sepia,‘ Nux vom., Sanguinaria, Naja, (214) CEPHALALGIA. 215 Kali iod., Ouprum, Lachesis, Lilium tig., Natrum sulph., Opium, Stramonium, Veratrum vir., Nitric ac., Phosphoric ac., Psorinum, Spongia, Lachnanthes, Sulphur and Phosphorus. Remedies and indications for nervous headache.—See hemicrania. Remedies successfully employed in the various forms of sympto- matic and sympathetic headaches are given below in connection with the therapeutic indications. Therapeutic Indications. —Gham0mi1la.-—Pains stinging, stitching, tearing and pressing; seat, forehead, temples and vertex; aggravated by mental exertion; ameliorated by mo- ' tion ; especially suited to children; arthritic and rheumatic headaches, especially when attended by vertigo, nausea and vomiting. . Berberis.—Pains lacerating, darting, tensive or aching; face pale, cheeks sunken, eyes with bluish-black circles; arthritic, menstrual and rheumatic headaches, especially when complicated with hepatic troubles; aggravated by motion, stooping, after- noon; ameliorated in open air. Ipecacl1anha.—Pains stinging, throbbing, lacerating ; accom- panied by nausea, vomiting, drowsiness, heaviness of the head; aggravated by stooping or moving the head; ameliorated out of doors. Natrum sulph.—— Characterized by fulness, heat in the vertex, pressure, vertigo, nausea, vomiting; menses late and scanty; mood sad and depressed; worse in the forenoon ; menstrual headache occurring periodically, every spring. Lachesis.—Pains throbbing, beating, lacerating, pressing; seat, forehead, temples, vertex, over the eyes; giddiness just before the menses; nausea and vomiting; pain in left ovarian region; ameliorated by lying down; headaches catarrhal, hyste- rical, menstrual and rheumatic. - Sepia.—Pains pressing, stinging, stitching, often one-sided, usually the right; nausea and vomiting, with aversion to food; aggravated by noise and motion; ameliorated by rest, darkness and sleep; gastric, hysterical and rheumatic headaches, or headaches depending on derangement of the digestive or sexual systems. Belladonna.—- Pains sudden in their appearance and disap- 216 NERVOUS THERAPEUTICS. pearance, but last indefinitely; often accompanied by stupefac- tion and vertigo, redness and swelling of the face; aggravated by noise, light, shock or contact; catarrhal, gastric and rheu- matic headaches, especially in lymphatic or scrofulous subjects; cerebral congestion. Anacardium.— Gastric headache caused by indigestion; nausea, with retching, soon after drinking cold water; weak digestion, with fulness and distension of the abdomen; symptoms dis- appear after dinner and reappear two hours afterward. Aconite.-—Pains piercing, throbbing, stupefying; headache, with. fever, especially when produced by exposure to cold, suppressed perspiration or currents of air; accompanied by roaring in the ears, chilliness, restlessness, wakefulness; aggra- vated by noise, light or motion; catarrhal and menstrual head- aches, especially at the commencement. Causticum.—Pains throbbing, tearing, stitching; seat, chiefly in vertex, spreading to forehead and temples; accompanied by nausea and vertigo; aggravated by stooping, reading, looking up, shaking the head; ameliorated in the open air; arthritic and rheumatic headaches, especially in the scrofulous. Nux mosch.—Pains pressing, throbbing, tearing ; confined to small spots; bloating of stomach and abdomen; scat, chiefly in forehead and temples; aggravated by eating, emotional excite- ment, menstrual congestion, changes in the weather; hysterical ' headache, especially when complicated with gastric troubles. Silicea.—-Pains pulsating, pressing, tearing, frequently one- sided; accompanied by nausea, vomiting, frequent cold sweat about the head, or vibratory sensations in the head; aggra- vated by noise, light, motion, even the slightest jar; amelio- rated by warmth, darkness and sleep; gastric and rheumatic headaches. Sulphur.—— Catarrhal and gastric headaches, especially in scrofu- lous patients; or when associated with constipation, morning diarrhoea or haemorrhoids; or when caused by abdominal plethora, suppressed eruptions or mental exertion, or when beginning, increasing and ending with the daily course of the sun; aggravated by motion, stooping, wet and cold weather, heat of the bed or mental exercise; ameliorated by pressure and moderate warmth. CEPHALALGIA. 217 Phytolacca.—Pains sharp, shooting, or dull and heavy; seat, forehead and temples; accompanied by vertigo, dimness of vision, nausea; aggravated by damp weather; gastric and rheumatic headaches, especially in syphilitic subjects. Lycop0dium.—Pains chiefly pressing and lacerating ; seat, forehead and temples; characterised by great restlessness and disposition to faint; worse in the afternoon; gastric, bilious and rheumatic headaches. Colocynthis.—-Pains tearing, aching, drawing, compressive, often one-sided; accompanied by restlessness, anguish, vertigo, nausea, or vomiting of bitter, yellowish fluid; aggravated by motion, stooping, bending the head forward; ameliorated by pressure; arthritic and rheumatic headaches, especially those of an intermitting type. Euphrasia.—Catarrhal headache; headache accompanied by profuse watery coryza, smarting of the eyes, lachrymation, photophobia, or sneezing and discharge of mucus; aggravated by cold in the head. Iris Vers.—Pains shooting and throbbing, or dull and heavy ; seat, chiefly in the forehead; accompanied by nausea and vom- iting, first of sour, watery fluid, then of bile; paroxysms of pain, followed by copious emissions of urine and vomiting, with great burning and distress in the stomach; bilious and gastric headaches, always beginning with a blur before the eyes. Arsenicum.—Pains burning, beating, pressing, drawing or throbbing; sometimes associated with a fluent burning and excoriating coryza; often attended with a burning nausea and the characteristic thirst; ameliorated by warmth, wrapping up the head or by rubbing; cold water only relieves tempo- rarily; catarrhal, gastric and malarial headaches, especially those of an intermitting or periodical character. Bovista.—Menstrual headache, characterized by deep-seated, stupefying pains; putrid, bitter taste, with nausea and empty eructations; morning sickness, relieved by eating breakfast; aggravated by pressure and by sitting up. I Caulophyl1um.——Pains contractive or pressive, paroxysmal or intermitting; pressure behind the eyes, with dimness of sight; menstrual irregularities, with “moth ” spots on the forehead ; - 15 218 NERvoUs’ THERAPEUTICS. aggravated by stooping, light and noise; menstrual and rheu- matic headaches. Gelsemium.—- Catarrhal and hysterical headaches, appearing suddenly, with vertigo, dimness of sight and double vision; often accompanied by slight nausea; ameliorated by shaking the head; pain in the back of the head and neck, extending to the shoulders, also across the forehead and temples; relieved by profuse urination. Mezereum.—- Catarrhal headache in scrofulous and syphilitic ‘subjects; headache extending from the root of the nose into the forehead, as if everything would press asunder, with pain in the temples when touched; heat and perspiration on the head, with chilliness and coldness of the rest of the body. Kali carb.--—Catarrhal headache, especially in aged people inclined to obesity; pains are of a sticking character, worse when stooping or moving the head, better from raising the head and from warmth; constipation. Nux vom.——Pains pressing, drawing, stupefying, affecting the whole or any part of the head, but especially the forehead; accompanied by more or less dizziness, nausea and inclination to vomit; aggravated by motion, stooping, moving the eyes, noise, light and mental exertion; gastric and bilious headaches, attended by constipation, and brought on by a debauch, wine, coffee, sedentary habits, or too close mental application. Podophyllum.— Gastric, rheumatic and bilious headaches, espe- cially when associated with torpidity of the liver; or when alternating with diarrhcea, or when accompanied by bitter taste and risings, giddiness, glimmering before the eyes; nausea, bilious vomiting and purging; worse in the morning; better from pressure and from lying quiet in the dark. Stramonium.-—Hysterical and rheumatic headaches, especially in young and plethoric persons; swollen face, with glistening eyes; vertigo when walking in the dark; heat and pulsations about the vertex, accompanied by faintness and loss of sight and hearing; aggravated by cold; ameliorated by warmth and quiet. Platina.——Pains drawing, crampy, affecting chiefly the fore- head; face usually red and hot; numb feeling in the brain; CEPHALALGIA. 219 mood variable, sometimes cheerful, at others depressed ; aggra- vated by stooping and by being in a warm room ; ameliorated by going into the fresh air; hysterical headache, especially in young girls with erotic desires, or who are suffering from amenorrhoea or from profuse menstruation. Kali iod.-—Pains tensive, stinging, shooting and tearing; seat, every part of the head, especially the forehead; head- ache accompanied with infiammation of the frontal sinuses, nose, eyes and throat; swelling of the cervical glands; violent sneezing, with running of acrid water from the nose, excori- ating the skin; catarrhal headache, especially in scrofulous and syphilitic subjects. Gymnocladus.— Catarrhal headache, especially during the early stage, characterized by fulness, throbbing in the forehead and temples, vertigo, numbness, heat of face and exhaus- tion; frequent violent sneezing, originating high up in the nose; dizziness, with dimness of sight, nausea and eructation. Chelid0nium.—Pains heavy, drawing and pressing; accom- panied by nausea and bilious vomiting; aggravated by motion; ameliorated by rest, pressure and closing the eyes; bilious headaches, affecting especially the right side of the forehead and the right temple. . Eupatorium perf.——Pains shooting and throbbing; seat, chiefly in the vertex, temples and occiput; vomiting of food and bile; tongue coated white or yellow; attacks generally occur in the morning between 7 and 9 A.M.; aggravated by heat; amelio- rated by pressure; bilious and malarial headaches. Asaf(Btida.——Pains darting, stitching, j erking; they sometimes disappear by the touch, or are transformed into other pains; hypochondriacal and hysterical restlessness, with anxiety; ameliorated by walking in the fresh air; hysterical headache in hypersensitive subjects. Allium cepa.— Catarrhal headache, with coryza; copious watery discharge from the nose and eyes; worse in the evening; better in the open air. Bismuth11m.— Gastric headache, complicated with gastralgia; pain comes on immediately after eating and is relieved by vomiting; pains chiefly frontal; aggravated by motion. 220 nssvoos THERAPEUTICS. Hydra.stis.—Catarrhal headache, especially in debilitated sub- jects, or when troubled with mucous discharges; pale face, with worn and weary appearance; myalgic pains in the scalp and muscles of the neck; discharge of thick white mucus , from the nose; cachectic condition, with loss of appetite and fainting turns ; subacute and chronic cases. Gossypium.—-Menstrual headache, with drawing and stinging pains extending from the temples to the centre of the fore- head; nausea, with inclination to vomit; menses last only about twenty-four hours, and are scanty and painful. Merc11riuS.——Pains burning, stitching, tearing, pressing; accom- panied by catarrhal aflections of the head and throat; disposed to sweat easily; chronic cases, complicated with ozaena, the pain extending to the root of the nose and frontal sinuses; catarrhal and rheumatic headaches, especially when occurring in syphilitic subjects. ‘ Phosphorus.—Pains burning or throbbing, seated in the fore- head or temples, often semilateral; accompanied by nausea, vomiting, vertigo, with a tendency to _fainting, especially in the morning on rising; sudden changes of mood, from grave to gay, from laughing to weeping; aggravated by stooping, music, mental and moral disturbances or abuse of stimulants ; hysterical headache. Alumina.—Chronic catarrhal headache, especially in scrofulous subjects; head feels heavy, with oppression in the forehead; pressive, stupefying pain in the frontal region ; aggravated by being in a warm room, or by going up stairs or stepping; ameliorated by pressure. Bryonia.—Pains throbbing, digging, sticking, burning or pressing; scat, any portion of the head, but especially the temples; usually associated with soreness; aggravated by stoop- ing or by quick motion; gastric and rheumatic headaches, especially when accompanied by nausea or vomiting, or when arising from indigestion. Cedron.—Pains of a shooting character, located chiefly in the frontal region, often extending to the orbits; when severe they are often accompanied by palpitation and quickened respiration; malarial headaches, coming on with clocklike regularity. ' CEPHALALGIA. 221 Gamboge.—Gastric headache, with compressive and heavy pains in the forehead and temples; accompanied with vomiting, purging and fainting; drowsy, heavy feeling in the whole head, with pain in the small of the back; watery diarrhoea, with colic and tenesmus; ameliorated in the open air. Natrum m11r.——Menstrual headache, occurring periodically, during the menses, every spring ; characterized by fulness, heat in the vertex, pressure, vertigo, nausea, vomiting; menses late and scanty; sad and depressed mood ; worse in forenoon. Pulsatilla.—Pains of almost every variety, and often one- sided; accompanied by more or less vertigo, nausea, bad taste in mouth, without thirst; worse in bad weather; better from pressure, also in the open air; gastric, menstrual and rheumatic headaches, especially when due to menstrual irregularities, mental exertion, fat food, abuse of coffee or spirits, or exposure to damp, cold weather. Stillingia.—- Catarrhal headache in syphilitic and scrofulous constitutions; dull, heavy, stupefying pains in the frontal re- gion; dizziness, with throbbing in the head; headache accom- panied with inflamed and watery eyes and general soreness of the muscles; chronic cases which have been aggravated by mercurial treatment. Rumex.—-Pains generally dull, but sometimes sharp and piercing; aggravatedby motion; catarrhal headache, with great irritation of the larynx and soreness behind the sternum. Scutellaria.-——Hysterical headache, especially when caused by mental emotion; pain worse over the right eye; ameliorated by moving about in the open air; urine scanty before and profuse after the headache. Lilium tig.—-Menstrual headache, especially in cases due to menstrual irregularity arising from prolapsus or malposition of the uterus, and causing strangury and ineffectual urging to stool; pains in the forehead and temples, with vertigo and depression of spirits; constant bearing down in the lower part of the abdomen, with severe pressure in the ovaries, rectum and anus, with constant desire for stool; bearing-down pressure in the vagina, as if everything would be pressed out ; worse from rising up and from standing. 222 NERvoUs THERAPEUTICS. Kali bich.— Catarrhal and rheumatic headaches, the former ac- companied by ozaena; frontal headache, complicated by a chronic catarrhal condition of the nasal and other mucous surfaces; aggravated by moving, stooping or mental exertion; ameliorated by hard pressure. Crocus.——Menstrual headache, of a pressive, burning and throbbing character, aflecting the forehead, temples and top of the head; vertigo, with confusion and webs before the eyes; headache at the climacteric period, 1nost severe at the time corresponding to the monthly periods, lasting two or three days and nights; excitable and variable disposition. Argentum nit.—Gastric headache in nervous persons; usually attended with chilliness and trembling of the body, intense nausea and vomiting; giddy and very restless; worse in the open air; better from bandaging the head. ' Cocculus.—-Gastric and menstrual headaches, with a feeling of emptiness in the head; violent headache which compels the patient to sit up, aggravated by talking, laughing, noise and bright lights. Sanguinaria.— Gastric and rheumatic headaches, most severe on the right side, affecting especially the frontal region and tem- ples; accompanied by nausea and vomiting; attacks usually paroxysmal, with more or less chilliness and burning in the stomach; aggravated by motion, light and noise; ameliorated by quiet, darkness and sleep. Antimonium crud.-—Gastric headache, with aversion to food; tongue coated white; aching of the limbs, nausea and vomit- ing; anorexia, risings and inclination to vomit; symptoms ameliorated in the open air. Carbo an.—Menstrual headache, chiefly in forehead and ver- tex; pains pressing, throbbing, tearing; accompanied by vertigo, sometimes by nausea; vertigo and nausea on raising the head after stooping; menses too early and too long, but not too great, followed by debility and prostration. Calcarea phos.— Gastric and rheumatic headaches, with fulness and pressure in the head, and with vertigo when walking or moving; patient dull, peevish, quarrelsome and forgetful; aggravated by changes in the weather, eating and mental and bodily exertion; ameliorated by cold washing. vnameo. 223 VERTIGO. Syn0nyms.—Swimming of the Head, Dizziness, Giddiness; Fr., Vertige; Ger., Schwindel. Definiti0n.——The consciousness on the part of the patient of disordered equilibration of the body. Diagnosis.-—It is impossible to mistake this condition for any other subjective symptom. It is not always easy, how- ever, to determine whether labyrinthine vertigo is primary or secondary. To do this we have to consider the presence or absence of certain symptoms. Thus, tinnitus and deafness without vertigo indicate disease of the middle ear; the same is true of tinnitus and vertigo without deafness. But in order to clear up the diagnosis in these cases, we should test the con- dition of the conducting apparatus, ascertain the permeability of the Eustachian tube, and make an otoscopic examination of the membrani tympani, since it is not until this is done that we are prepared to estimate the significance of the syncope, nausea, vomiting and other like indefinite symptoms. Pathology.—It is not always easy to determine with pre- cision which of the sensory impressions is concerned in this or that particular case of vertigo. Sometimes the impressions are labyrinthine when they appear to be ocular, and vice versa. Doubtless in some cases the two forms are combined. This is the more probable from the fact that variations in labyrinthine tension may be caused by differences in the vascular tension of the labyrinthine bloodvessels, and a similar cause may, and often does, operate in the case of visual disturbances. Not only do labyrinthine, visual and tactile disturbances give rise to vertigo, but, as is well known, the latter is often caused by derangement of the stomach and other viscera. This is easily accounted for by the close and important nervous relations which the labyrinth sustains to these organs. For example, the nucleus of the vestibular nerve, which supplies the semi- circular canals, and which is a branch of the auditory nerve, is in close relation to the nucleus or internal origin of the pneumogastric. Finally, those diseases, as well as those medi- 224 rurnvous THERAPEUTICS. cines, which cause variations in the labyrinthine tension may also give rise to vertigo.* Clinical Experience:-We should never forget that vertigo is a 1nere symptom, indicative of some abnormal condition, the removal of which is essential to cure. The remedies which, irrespective of the cause, most frequently relieve are: Phos- phorus, Nucc vom., Arsenicum, China, Chininum sulph. and Pulsa- tilla. The following can usually be relied upon in the several conditions named : Nervous Vcrtigo.—Nux vom., China, Chininum sulph., Arseni- cum, Ferrum, Phosphorus, Phosphoric ac., Pulsatilla, Ignatia, Zincum, Silicea. Gastric Vcrtigo.——Nux vom., Bryonia, Arsenicum, Ipecacu- anha, Pulsatilla, China, Carbo veg., Sepia, Ignatia, Phosphorus, Calcarea, Tarantula, Sulphur and Natrum mur. Epileptic Vcrtigo.——Belladonna, Stramonium, Hyoscyamus, Arsenicum, Amyl nit. and Glonoin. Ocular Vertigo.—Causticum, Gelsemium, Argentum nit., Phos- phorus, Physostigma, Nux vom., Rhus tox., Spigelia, Paris quad., Senega, Euphrasia and Cuprum acet. Auditory or Labyrinthine Vertigo.-—-Natrum sal., China, Chini- num sulph., Rosa damas., Colchicum, Aconite, Kalmia, Sali- cylic ac., Conium and Cicuta. Therapeutic Indications.—Ph0sphorus.—Vertigo accom- panied by reeling, nausea, vomiting; vertigo occurring in the morning, with an empty stomach, after eating or sleeping, during or after the menses, or with fainting and trembling; ocular, gastric or nervous vertigo, especially when caused by nervous debility, sexual abuse, spermatorrhoea or haemorrhoids; worse after eating. Nux Vom.—Vertigo, with tendency to faint, worse during and after meals; vertigo associated with dyspepsia and constipa- tion; vertigo brought on by mental exertion, sedentary habits, high living or haemorrhoids; vertigo in nervous and hysteri- cal subjects; ocular, ncrvous or gastric vertigo, or when caused * From the author’s work on Intracranial Diseases, pp. 269-271, where this sub- ject is treated somewhat at length. VEBTIGO. 225 by paresis of the ocular muscles from the use of stimulants or tobacco; worse after dinner. Silicea.—Vertigo accompanied by nausea, and aggravated by motion or by looking upward; dizzy sensation from the nape of the neck into the head ; vertigo during sleep, or when rising from a recumbent position ; nervous or ocular vertigo, especially when brought on by severe physical or mental labor, reading, writing or sewing. Natrum sal.—Vertigo, with inclination to fall toward the left side; labyrinthine vertigo, with tendency to fall to the affected side, while surrounding objects appear to move in the opposite direction; noises in the affected ear, with defective hearing; worse on raising the head 'or sitting up. Natrum carb.—Vertigo, with great lassitude; weakness of digestion, with nausea in the morning and inclination to vomit; gastric and nervous vertigo, the latter from the effects of exposure to the sun. Lachesis.'—-Frequent momentary vertigo, especially on closing the eyes, sometimes with paleness, nausea and vomiting; ver- tigo, with headache, cerebral congestion and cold extremities; epileptic vertigo, with reeling, falling and loss of consciousness. Veratrum-Vertigo, with sensation as if everything in the head was loose; loss of appetite, with burning stomach, dis- tended abdomen, flatulency, vomiting and diarrhoea; gastric vertigo, with cold perspiration on the forehead. Senega.— Ocular vertigo, especially when caused by paresis or paralysis of the superior rectus or superior oblique muscle of the eye, or when the vertigo and double vision are relieved by bending the head backward. Ignatia.—Vertigo followed by nausea and vomiting of slimy, sourish fluid; burning in the stomach; abdominal distension, with flatulency and constipation; restless, changeable disposi- tion; vertigo caused by mental emotion; gastric, nervous or epileptic vertigo ; worse from stooping or moving the head. Cupr11m.—Vertigo when looking up, with loss of sight, as if gauze were before the eyes; vertigo, with sensation of turning round, or revolving vertigo; vertigo from cerebral congestion; extreme weakness, especially of the lower extremities; ocular vertigo caused by paralysis of the nervus abducentis. ' 226 NERvoUs THERAPEUTICS. China.—Vertigo from nervous weakness or from general debility; vertigo from anaemia, with pale face, ringing in the ears, nausea, vomiting or fainting; vertigo with an empty stomach; gastric, nervous or auditory vertigo, especially when caused by debility from loss of animal fluids. Chininum sulph.—Vertigo occurring periodically, with chills and fever, especially when due to malarious influence; vertigo, with headache, cerebral congestion and deafness; auditory ver- tigo, with hammering and humming in the ears and partial deafness. Conium.—Vertigo caused by looking steadily at an object, or on rising up or going down stairs, or when lying down or turning over in bed; great debility and inclination to sleep-; ocular or auditory vertigo, with sensation as if turning in a circle. Arsenicum.—Vertigo, with inclination to fall, especially when closing the eyes; nausea and disposition to vomit in a recum- bent position, less when sitting up; burning in the stomach, with vomiting; vertigo coming on periodically, with coldness, followed by fever, loss of appetite and vomiting; gastric, nerv- ous or epileptic vertigo, with reeling, as if intoxicated. Bryonia.——Gastric vertigo, with nausea and disposition to faint ; weakness and distension of the stomach, flatulence and constipation; burning in the stomach, with vomiting; aggra- vated by rising from a recumbent position and by motion; ameliorated by rest and by lying down. Apomorplfla.-—-Labyrinthine or gastric vertigo, attended with tinnitus and slight deafness; nausea, with retching and vomit- ing, coming on at intervals; sudden vomiting, almost without nausea; syncope, with lessening of blood pressure. Bellad0nna.——Vertigo accompanied by luminous vibrations before the eyes, especially when stooping or bending the head; vertigo, with vanishing of sight, and a tendency to fall back- ward or to the left side; epileptic vertigo, ‘caused by rush of blood to the head, with heat and redness of the face. buzzing in the ears, dimness of vision and loss of consciousness; aggra- vated in a warm room; ameliorated in the open air. ' Euphrasia.— Ocular vertigo from paralysis of the ocular mus- VERTIGO. 227 cles, especially when caused by taking cold, or when associated with coryza; blurring of the eyes, relieved by winking. Stram0ni11m.——Vertigo followed by stupefaction of all the senses and by complete insensibility; vertigo accompanied by strange fancies; epileptic vertigo, especially when walking in the dark, day or night. 0pium.—-Vertigo, with stupefaction of the senses, or after fright; vertigo, with apoplectic symptoms; pale or bloated face, with dimness of sight and tendency to faint; ameliorated by rest; ocular vertigo, depending on paralysis of the accommo- dation. Tarantula.—Vertigo after breakfast, with a bad taste in the mouth; vertigo from fixing the sight on" any object; gastric, nervous or epileptic vertigo, so severe as to cause him to fall, but without losing consciousness; nausea, bloating of the stomach and disposition to vomit. Sepia.-Vertigo, with flatulency and constipation; worse ‘when drinking, while looking upward, or while looking from a great height, a large assemblage of people or an extended plain; gastric or nervous vertigo, especially when caused by a dyspeptic condition; worse when drinking. Hy0scyamus.——Epileptic or ocular vertigo, with reeling, loss of sight, hearing and consciousness; double vision; red, spark- ling, staring and distorted eyes. Kali i0d.—— Ocular vertigo, especially in syphilitic patients; dimness of vision, with twitching of the eyeballs; burning in the eyes, with sensation of a film before the eyes, relieved by winking; glandular swellings on neck. C0ccul11s.——Vertigo aggravated by noise, motion, smoking, cof- fee, sitting up in bed and riding in a carriage; epileptic vertigo, with nausea, reeling, loss of consciousness and sudden falling, tq the ground. Argentum nit.—— Ocular vertigo, caused by weakness or paraly- sis of the ciliary muscle; transitory blindness, nausea and con- fusion of the senses; sensation of expansion when looking high up in the street; trembling weakness when walking with shut eyes, or when walking in streets with high houses, as though they would fall upon him. 228 NERVOUS THERAPEUTICS. Gicuta.——Auditory vertigo, associated with aural disease, dis- charge of blood from the ears, loud sounds when swallowing, and hardness of hearing; tinnitus aurium; worse in the room than in the open air. Ipecacuanha.—Vertigo, with loss of appetite, empty retching and qualmishness; gastric vertigo, with nausea and vomiting; abdominal distension, with flatulency, colic and diarrhoea. Golchicum-—Vertigo, with roaring and stoppage of the ears; ameliorated by rest; auditory vertigo, with chronic discharge from the ears and hardness of hearing. Kalmia.—Vertigo while stooping or looking downward; pal- pitation of the heart; auditory vertigo, with sensation when turning as of something loose in the head. Natrum mur.——Vertigo, with nausea and heartburn after eat- ing; gastric vertigo, with reeling and dimness of sight; sensa- tion of everything turning in a circle when walking; nausea and sudden sinking of strength ; burning and feeling of press- ure in the stomach; want of appetite and aversion to food. Physostigma.— Ocular vertigo from partial or complete paraly- sis of the ciliary muscle; has been applied with benefit as a local application in such cases. Sulphur.—Chronic vertigo, especially if preceded by a sup- pressed eruption; gastric vertigo, especially in the morning after breakfast, with nausea; dimness of vision, with inclina- tidn to fall to the left. Phosphoric ac.—Vertigo, with great disposition to sweat dur- ing the day; night-sweats, with vertigo; vertigo from onanism, loss of animal fluids, or mental exertion, anxiety or’ over- work; nervous vertigo, especially when caused by cerebial or nervous exhaustion. Gelsem1'um.—Vertigo, with reeling and staggering even to falling; heaviness of the head, with imperfection of sight and dulness of mind; ocular or nervous vertigo, the former from paralysis of the ocular muscles; aggravated by smoking. Gausticum.—Ocular vertigo caused by paralysis of any of the ocular muscles; congestion of blood to the head, with heat; vertigo brought on by taking cold; sudden and frequent loss of sight, with sensation of a film before the eyes; inclination on COMA SOMNOLENTUM. 229 stooping to fall backward, and on looking up to fall toward the left side. Amyl nit.—Vertigo, with sensation as if a vapor spread from her through her head, rendering her powerless; slight nausea, with uncomfortable feeling in the stomach; precordial anxiety; she turned deadly pale, felt very giddy, then became partially unconscious, remaining so for ten minutes; mental confusion and a dreamlike state; auditory vertigo, with a bursting sensa- tion in the ears, as if the drums would be forced out with each beat of the heart; great throbbing in the ears and head, with confusion. Calcarea carb.—-Vertigo, with stupefaction of the head; sensa- tion of coldness in the brain; vertigo, with tinnitus and nausea, especially when stooping or rising up suddenly; ver- tigo caused by cerebral congestion; distension of the stomach and bowels, flatulence and constipation; gastric or epileptic vertigo. Aconite.—Vertigo on raising the head, or on rising from a recumbent position; vertigo, with sensation of intoxication, the patient staggering like a drunken man; nausea; great fear of falling; auditory vertigo, with reeling; worse when bending forward or going down stairs. Compare, also, Graphites, Iodium, Chamomilla, Bovista, Cy- clamen, Ruta, Mezereum, Lycopodium, Secale, Platina, San- guinaria, Thuja, Staphisagria, Tartar em., Mercurius, Hepar, Coffea, Boracis, Arnica, Spongia, Asterias rub., Agaricus, Sam- bucus, Theridium, Spigelia, Apis. Auxiliary Treatment.--The application of the galvanic current is usually of great service in all forms of vertigo, either as central galvanization, or 'by the application of both poles on each side of the sixth and seventh cervical vertebrae, using from ten to fifteen cells, as the case may require. COMA SCMNOLENTUM. S,ynonyms.——-Stupor, Sopor, Somnolency, Lethargy, Carus, Somnolentia, Lethargia, Carus Lethargus; Fr., Stupeur; Ger., Stumpfsinn. 230 NERvoUs THERAPEUTICS. Definition.—A greater or less degree of insensibility, arising from a partial or complete loss of consciousness, due to an abnormal amount and kind of sleep. Diagnosis.—It is not always easy to distinguish the various degrees of insensibility, or unconsciousness, due to abnormal sleep, from similar conditions resulting from other causes. For example, coma is a state of complete insensibility, but complete insensibility is not always coma, and the same is true of minor degrees of unconsciousness. As a general rule, how- ever, we will find, in addition to the comatose state, certain characteristic symptoms belonging to the primary affection, the presence of which will serve to distinguish the condition from that of simple coma. Thus in syncope there is fainting; in asphyxia, deficient respiration; in narcosis, the peculiar effects of the agent or drug producing it; and in uraemia, con- vulsive movements, vomiting, etc. Pathology.—Natural sleep is a physiological, not a patho- logical condition; but stupor, lethargy, coma, etc., denote different degrees of insensibility somewhat allied to sleep, but in which the loss of consciousness is more profound than in any form of true sleep. The terms stupor, sopor, lethargy, etc., are employed to designate various degrees of insensibility and unconsciousness from that of sleep properly so called, up to that of profound anaesthesia, in which there is complete loss of consciousness and true coma. Not only does stupor vary in degree, but coma also. Thus we have what is known as the comatose state, coma and profound coma, the last of which was designated by the older writers carus, the gravest of the graver states of unconsciousness and inserisibility. These are all pathological conditions or, rather, symptoms of such conditions, the pathology of which corresponds with that of the primary diseases to which the symptoms belong. Clinical Experience.—The chief clinical distinctions are as follows: For stupor manifesting itself in the morning: Nux vom., Natrum, Hepar, Phosphoric ac., Sulphur, Natrum mur. For somnolency coming on early in the evening: Pulsatilla, Lachesis, Calcarea, Silicea, Phosphoric ac., N ux vom. COMA SOMNOLENTUM. 231 For coma somnolentum: Belladonna, Opium, Laurocerasus, Barium carb., Crocus, Ledum, Veratrum. ' For profound coma: Opium, Belladonna, Lachesis, Lyce- podium. Therapeutic Indications.—Bryonia.——Moanings and start- ings in sleep, with fever, and sometimes with loud cries; great drowsiness or heavy stupor, with or without delirium. PulSatilla.—Deep sleep, with snoring inspirations; charac- teristic symptoms, cerebral, gastric, intestinal and urinary; valuable in cases complicated with erysipelas. Veratrum.-—Protracted stupor, especially when accompanying the collapse of diarrhoea or cholera; coldness of the whole body. Stram0nium.——Deep sleep, with stertorous respiration and bloody froth at the mouth ; epileptic coma. Belladonna.—One of the most reliable remedies for stupor arising from cerebral congestion; stupor, with snoring, dark red face, dilated pupils; drowsy, yet unable to sleep; delirious sleep ; eyes half open, but insensible to light. Lachesis.—Comatose symptoms, especially when resulting from erysipelas of the head and face; constant sopor, with moaning and tossing about, especially in children. Rhus tox.—Especially valuable in the coma of typhoid fever and erysipelas; sopor, with snoring, muttering and grasping at flocks. 0pium.—Profound coma, such as occurs in apoplexy, with stertorous breathing, dilated pupils, dark red, bloated face, and feeble, irregular pulse; mouth open, eyes half closed, pupils insensible to light. 0hamomilla.—Soporose condition in children, with feverish restlessness; snoring and starting in the sleep; delirium, with moaning, talking or screaming; comatose condition during dentition, especially when associated with diarrhoea. Tartar emet.—Coma, with constant yawning and stretching; especially indicated when the symptom is caused by irritation or congestion of the brain; great prostration, with trembling of the limbs; coma of delirium tremens. Camphora.—Sopor and delirium, with chilliness and coldness of the body; talking and snoring in the sleep; cerebral con- gestion; face red, but sometimes pale. 282 rznnvous THERAPEUTICS. Phosphoric ac.-—Sopor, especially in the daytime; being roused, he answers correctly, but immediately falls asleep again; typhoid fever, especially when attended by profuse sweating. HelleboI'11s.—Sopor, especially when resulting from an attack . of hydrocephalus, either acute or chronic; fever, with hot head and cold hands and feet; urine suppressed. Secale cor.—-Long-continued stupor, with startings and de- lirium; cold, viscid sweat; face red or pale; foetid and colliqua- tive diarrhoea; suppression of urine. Nux mosch.—Sopor, with or without delirium; valuable in low forms of fever, especially when accompanied by putrid or colliquative diarrhoea; also in children during_the diarrhoea of teething. , Lycopodium-—Very drowsy during the day, with yawning; sleep disturbed by loud screams; starting and jerking of the limbs during sleep; great nervous irritation, with peevish mood; fevers. Compare, also, Ignatia, Arsenicum, Cuprum, Sepia, Arnica, Carbo veg., Ledum, Conium, Capsicum, Alumina, Colocynth, Crocus, Sambucus, Antimoniu1n, Cannabis, Hydrocyanic ac., Lactuca and Asafoetida. INSOMNIA. Synonyms.—Sleeplessness, VVakefulness, Pervigilium ; Fr., Insomnie; Gen, Schlaflosiglceit. Definition.—./in unnatural deficiency or loss of sleep. Diag‘nosis.—Healthy sleep varies within certain limits in different individuals; and this variation is occasionally so great, that what would be a normal amount of sleep in one would constitute an excess or a deficiency of sleep in another. The diagnosis therefore must be based on the average or nor- mal habit of the patient himself, and not on that of others. Pathology:-As in other symptomatic affections, insomnia is a mere symptom of some other abnormal condition or dis- ease. It may be partial, as when the patient is able to obtain only a portion of his usual allowance of sleep; or it may be INSOMNIA. 233 complete, in which case he may be unable to obtain any sleep whatever for several successive nights, as in acute mania, violent fevers, or when suffering from severe pain, profound grief or great mental disturbance. In these cases the primary disease is the one to be chiefly considered. Clinical Experience.—In the absence of other indications, the following clinical distinctions will be of service: Sleeplessness before midnight.—-Passiflora incar., Gelsemium, Belladonna, Mercurius, Phosphorus, China, Ignatia, Pulsatilla, Spigelia, Graphites, Valerian, Conium, Carbo veg., Calcarea -carb.; Sulphur, Bryonia, Cyclamen, Selenium, Moschus, Staph- isagria, Aconite, Opium. Sleeplessness after midnight.—Passiflora, Rhododendron, Asa- foetida, Platina, Rhus tox., Mercurius, Arsenicum, Coffea, He- par, Nux vom., Kali carb., Aurum, Nitric ac., Thuja, Hyoscy- amus, Sambucus, Capsicum. Waking freguently.—Passiflora, Gelsemium, Belladonna, China, Fluoric ac., Teucrium, Manganese, Digitalis, Bismuth, -Causticum, Calcarea carb., N ux vom., Pulsatilla, Phosphorus) Zincum, Arnica, Rhus tox., Nitric ac. Waking too early.——Ranunculus bulb., Muriatic ac., Dulca- mara, Sepia, Asafoetida, Phosphoric ac., Silicea, Natrum carb. Retarded sleep.-—Passiflora, Gelsemium, Belladonna, Pulsa- tilla, Nux vom.,- China, Ignatia, Sepia, Causticum, Graphites, Phosphorus, Selenium, Lachesis, Carbo veg., Caladium, Mer- curius, Rhus tox., Sulphur, Creosotum, Aconite, Moschus, Opium, Veratrum vir. Therapeutic Indications.—Passiflora incar.—Sleeplessness, with great restlessness; suicidal mania; neuralgia, preventing sleep. This is one of the most reliable remedies for insomnia, the patient falling into a quiet slumber, from which he usually awakes in a natural and rational condition. GelsemiuIn.——Drowsy and sleepless, or else wide awake and unable to get to sleep; insomnia from cerebral irritation and congestion; insomnia from overwork or debauch; insomnia of college professors, authors or business men. Belladonna.-—Insomnia, with drowsiness; cerebral congestion. One of the most reliable remedies for insomnia when properly 16 234 NERVOUS THERAPEUTICS. given, the higher potencies being required in all cases where the brain is oversupplied with blood or actively congested, and the lower ones when it is overpowered by the intensity of blood pressure, pupils widely dilated and convulsions threatened. Aconite.—Sleeplessness from febrile and inflammatory condi- tions; anxiety, with great restlessness and tossing about; sleep- lessness of infants and aged people; sleeplessness due to mental excitement, especially when there is active cerebral congestion, with intense anxiety and fear of death or disaster. Gimicifuga.——-Sleeplessness associated with pain in the base of the brain, extending to the nape of the neck, and sometimes over the shoulders; extreme prostration, both physical and mental. An invaluable remedy in the insomnia of drunkards, especially when it takes the form of delirium tremens, and also in that of opium-eaters, or those who are trying to abandon the use of it. Nux vom.-—Sleeplessness from overwork, both mental and bodily; too close study, especially at night; abuse of stimu- lants; especially useful in cases of recent debauchery and gluttony. Phosphorus:-Gets to sleep too late or not at all; insomnia from nervous debility, especially when caused by onanism or sexual excesses; sleeplessness following intense mental strain, overwork or anxiety, or when associated with pain and con- fusion in the head; wakens frequently during the night, and can get no sound and refreshing sleep. Opium.—Great wakefulness or drowsiness, with inability to get to sleep; insomnia, with acuteness of hearing, the ticking and striking of the clock, cock-crowing and other noises keep- ing the patient awake. This remedy, used somewhat high, also mitigates the stupor of cerebral congestion, especially where there is a tendency to apoplexy; particularly suited to the sleeplessness of old people. Veratrum vir.—Sleeplessness from cerebral congestion, or from a general febrile ‘condition; particularly useful in the insomnia of acute fevers, puerperal mania and the excitement attending attacks of epilepsy. INSOMNIA. 235 Hy0scyamus.——Sleepless from nervous excitement; wild, star- ing eyes; tendency to delirium; especially suited to nervous and overworked persons, particularly women suffering from undue lactation, household cares, etc. Ignatia.-——Sleepless from grief or depressing emotions; in- somnia caused by nervous exhaustion, loss of health, property or friends. Pulsatilla.-—Sleeplessness arising from late suppers or from indigestion; determination of blood to the head and surface of the body, rendering the patient restless, sleepless and very uncomfortable; particularly suited to insomnia occurring in mild and tearful young women, especially if there happens to be any derangement of the menstrual function. Cocculus.—-Sleeplessness arising from mental activity or from night-watching; sleep retarded, and frequently interrupted by wakings and startings. Zincum val.-—-Insomnia, with pains in the head, particularly in children; frequent waking in the night; drowsy, with pale and tired expression of countenance. 00ffea.—Sleeplessness of infants; sleeplessness arising from joy, long watching and overexcitement of mind; acute nerv- ous erethism, preventing sleep. ll/Iosclms.-—Nervous excitement preventing sleep ; is awakened by sense of heat, rendering the covering uncomfortable; re- lieved by throwing off the covering. Stramonium.—Sleepless from intense nervous excitement; sleep interrupted by frightful screams; restless sleep full of dreams; tendency to delirium; best suited to cases attended with unusual mental disturbances, or where there is a tendency to maniacal excitement. Silicea.—Sleeplessness arising from extreme physical and mental prostration; great depression of spirits; sleeplessness from inanition. C0ca.——Sleeplessness from mental exhaustion or from anae- mia; patient sometimes awakened after going to sleep by a sense of shock in the brain ; suited to weak and nervous women, worn-out brain-workers, night-watchers and those who have lost much sleep. 236 mravous THERAPEUTIOS. Sulphur.—Sleepless from nervous excitement, cutaneous irri- tation and external heat; sleepy in daytime, sleepless at night. Arsenicum.—Insomnia from nervous exhaustion caused by general anaemia; will seldom benefit cases not due to blood degeneration, and hence must be given with a view of over- coming this condition. Auxiliary Treatment.——The three principal causes of sleeplessness are, imperfect circulation, indigestion and anaemia. Much may be done in the way of accessory treatment to remedy these difficulties, and thus secure sound sleep. Thus imperfect circulation, whether it take the form of cerebral hyperaemia, -cold feet, or both combined, as is usually the case, may be cor- rected by a warm bath or by a brisk rubbing just previous to retiring for the night. Sometimes a cold douche just after the bath will be still more effective. Massage and gymnastic excr- cises are also useful for the same purpose, though as a general rule the latter had best be practiced in the morning, unless the patient leads a sedentary life, in which case the evening practice is the most suitable. The effects of indigestion in preventing sleep may usually be remedied by partaking of very early and very light suppers, but this is a matter in which every individual is a law unto himself; experience alone can determine what form, character and amount of food will best agree with any one patient, and the same is true as to the time of eating. Sleeplessness arising from general anaemia may be success- fully combated by the administration of liquid food, such as hot milk, beef-tea and broths, an hour or so before bedtime. In these cases, also, the patient should sleep with his head low, whereas in cases of hyperaemia the head should be well elevated. As for the bed, the bed-clothing, etc., the aim should be to secure perfect comfort to the patient. No part of the body should be chilled, nor should any portion of it be overheated. Plenty of fresh air should be supplied to the sleeping room, while at the same time the sleeper should be protected from draughts, even moderate ones, as they always have a tendency to disturb the circulation, which is inimical to sound sleep. PART VII. MENTAL DISEASES. MELANCHOLIA. Synonyms.-—Melancholy; Fr., Lypémanie, Mélancolie; G'er., Schwermuth, Melancholie. Definition.—A form of mental alienation, characterized by excessive gloom, despondency and apprehension. Diagnosis.—Although formerly regarded as a species of monomania, or partial insanity, it may be distinguished from it by the fact that there is in simple melancholy little or no disorder of the intellect, the emotion is disproportioned to the cause, and hence there is often associated with it a suicidal tendency. But melancholy with delusions, constituting hypo- chondriasis, is most frequently met with, and is the form we are usually called upon to treat (see hypochondriasis). Pathology.-—The physical state with which nearly all cases of melancholia are associated is one of anaemia, but just what relation the anaemia sustains to the mental condition is not fully determined. We know that powerful moral emotions, associated with great mental depression, will, if long con- tinued, derange the bodily functions and lead to inanition and exhaustion. On the other hand, when, as in these cases, there is a strong predisposition to the disease, there is no doubt that defective blood nutrition affords a sufficient ex- planation of simple melancholy, which is a state of mere depression. 1 Clinical Experience.—The remedies of greatest repute in melancholia are: Aurum, Ignatia, Arsenicum, Kali phos., Lyco- podium, Pulsatilla, Nux vom., Belladonna, Natrum mur., Cimi- cifuga, Phosphorus, Platina, Ambra, Plumbum, Iodium, Kali brom., Agnus cast., Amyl nit. and Veratrum. (237) 288 NERVOUS THERAPEUTICS. Therapeutic Indications.—Aurum.—Extreme melancholy, fearful, taciturn, mistrustful; suicidal tendency, has a great loath- ing of life; anaemia, vertigo, vascular and nervous depression; hypochondriasis; religious melancholy. Ignatia.-—Silent grief; desires solitude that he may nourish his sorrow; aversion to every form of amusement; anxiety, with taciturnity; sexual impotency; hypochondriasis. Arsenicum.—Very despondent; does not wish to recover, as she thinks she is in the way, and her family would be better off without her; poor appetite; says she is getting weak and cannot control her mind ; tongue red; has an intense desire for small quantities of water at short intervals; persistent burning pains in the stomach and bowels ; hypochondriasis. Kali pl10s.;Melancholic, depressed mood, with excitement and sleeplessness; no appetite; weeps a great deal from religious melancholy ; constant lamentations, self-reproaches and crying; staring, unconscious look; irritable, fretful, timid, distrustful, weeping mood, with disgust of life and fear of death; hypo- chondriasis. Lycopodium.—Weeps the whole day; cannot calm herself; worse from 4 till 8 o’clock P.M.; full of ungrounded fears ,- pusillanimous. Pulsatilla.—Religious melancholy; greatly concerned about his worldly and eternal well-being; weeps, prays and laments; early in the morning, depression of spirits and full of cares about domestic affairs; pale face, cold hands, flushes of heat; pre- cordial anguish, with thoughts of suicide. Nux vom.—Taciturn and fond of solitude; easily vexed and disposed to quarrel with every one; afraid of coming to want ,- has a kind of fainting feeling, with nausea and flushes of heat, going off when lying down; pale, sunken countenance; lack of appetite, slow pulse and constipation; involuntary sighing and moaning; hypochondriasis. Be1lad0nna.—C’erebral congestion; restlessness which drives him from place to place, and will not allow him to sit or lie down for more than a few minutes at a time; full of mistrust and apprehension; starts easily; extremely low-spirited, with disposition to take his own life; great irritability, with mental anguish. MELANCHOLIA. 239 Natrum mur. — Excessive despondency; full of gloomy thoughts; will not listen to consolation; likes to dwell on past unpleasant occurrences; sallow complexion; loses flesh, though living well ; hypochondriasis. Cimicifuga.—Puerperal melancholy ; imagines the whole world is against her and that she will become insane; cries, sobs, feels perfectly helpless, and believes her case is beyond medical skill; puerperal hypochondriasis ; bowels costive, tongue furred, spine sensitive to pressure. Ph0sphorus.—Extreme melancholy ; gloomy, taciturn, anxious, discontented and irresolute; loathing of life, but anxious for the future; cold feet and hands, with trembling of the limbs; frequent empty eructations; constipation; impotence. Platina.—-Melancholy, with dread of death; weeping mood; anorexia; anxiety, with trembling; disorder of the sexual system. Ambra gris.-—Extreme depression of spirits; sits day after day weeping, with great muscular debility and pain in small of the back; feels worse from the presence of other people; sleep— less and constipated. P1umbum.—Religious melancholy ; great weakness of the sexual organs; extreme constipation; frequent attacks of colic; restless, hopeless and indifferent to everything. I0dium.—-llfelancholy and discouraged; has no ambition; wishes to be left alone; shuns every one, especially the physician; is very apprehensive, restless and thinks that he will become insane. Kali br0m.—Mental depression from cerebral exhaustion; suicidal tendency; religious melancholy, with sense of moral unworthiness; nervous system all unstrung; sheds tears and gives way to her feelings in a childish manner; indifferent to life. Agnus cast.- -Extremely low-spirited, with sense of approach- ing death; vertigo, with loss of memory; starts in sleep, as if from fright; great physical debility, with prostration of mind and body; puerperal melancholy. Amyl nit.—Coldness and chilliness, followed by fever; great depression of spirits, with heat of head and burning of the 240 NERVOUS THERAPEUTICS. hands and feet; features contracted, face pale, eyes lustreless, and mind dull and obtuse. This remedy is best administered by inhalation, two or three drops, on cotton, three or four times a day. Veratrum.—Great anxiety, despondency and despair; religious melancholy; distrusts every one; cold sweat all over; moaning during sleep; frightful dreams; fearfulness, with tendency to start at every new sight or person; frequent eructations; puerperal melancholia. ' Compare, also, Helleborus, Cannabis inal., Abrotanum, Colocynth, Lachesis, Indigo, Stramonium, Bromine, Lithium, Kali iod., Lobelia, Sulphur, Leptandra, Hepar, Causticum, Calcarea, Alumina and Hyoscg/amus. Auxiliary Treatment.—This may be summarized as fol- lows: (1) Rest as a means of mental and physical recupera- tion; (2) exercise, amusement and occupation as stimulants in the renewal of health; (3) nourishing diet and, where necessary, artificial feeding; (4) sanitary hygiene, including the warm bath, massage, etc.; and (5) mental and moral hygiene, especially such as is calculated to divert the mind of the patient from his own troubles, furnish an adequate motive for his exertions and, at the same time, produce little or no fatigue; in short, the chief aim should be to impart vigor of body and cheerfulness of spirit to the patient, not only in the ways above mentioned, but, if necessary, by change of scene, travel, cheerful society, and such other measures as the exigen- cies of the case may require. HYPOOHONDRIASIS. Synonyms.—Hypo, Spleen, Morbus Hypochondriacus; Fr., Hypochonolrie; Gen, Milzhranlcheit, Milzsucht. Definition.—-A form of melancholia, characterized by hallu- cinations relative to the state of the patient’s physical health. Diagnosis.——The diagnosis between hypochondriasis and simple melancholy is usually evident enough, since the pecu- liar hallucination which characterizes the former is always absent in the latter. Moreover, in the former there is no ten- MORAL INSANITY. 241 dency to suicide. On the contrary, the chief concern of the patient has regard to the prolongation of his life, and this impels him to endless search for the cure of his ailments, whether real or imaginary. Pathology.—As there are no anatomical characters peculiar to the disease, the pathology does not essentially differ from that of simple melancholia, which see. Treatment.—See previous section, as the clinical experience, therapeutic indications and accessory treatment given under the head of melancholia apply equally to hypochondriasis, which is but a special form of melancholy. MORAL INSANITY. Synonyms.—Emotional Insanity, Impulsive or Affective Insanity; Fr., Manic sans Délire, Folie Raisonnante, Monomanie Aflective; Gen, Gemiithswahnsinn. Definition.—A species of insanity in which the intellect is apparently unimpaired, but the moral and emotional part of the brain is disordered. Diagnosis.—Moral insanity differs from every other form of the disease in the absence of delusion. Notwithstanding this, the morally insane can scarcely be considered of sound intel- lect, as their conduct is not only odd, peculiar and unlike that of other people, but is often foolish and very unwise, the patient, for example, spending his capital as if it were income, or approving acts which admit of no justification. Another diagnostic point is, that they seldom, if ever, are insane on more than one point. If, for example, they are pos- sessed of a suicidal tendency, they have no desire to kill others; if they have a propensity to steal, they have no disposition to commit acts of violence; in other words, they are true mono- maniacs. Pathology.—Whether caused by hereditary transmission, as is usually the case, or by physical disease, there is in both instances some abnormal condition of the moral portion of the nervous centre. Pathology shows that, as the intellectual functions are not materially disturbed, the disease must be 242 NERVOUS THERAPEUTICS. seated in the cells of the cortical portion of either the lateral and posterior portions of the cerebrum, or in those of the cor- tical portion of the cerebellum and medulla oblongata. The former is probably the true seat of the malady, as disease or irritation occurring in the cerebellum and medulla oblongata produces a want of controlling power over the muscles, and not over the mind. Clinical Experience.—The homoeopathic materia medica is exceedingly rich in emotional remedies, but we shall merely indicate here a few of those which experience has shown can generally be relied upon to meet the special symptoms that characterize the most common forms of emotional insanity. For angry mood: Nux vom., Ignatia, Bryonia, Arsenicum, Veratrum, Staphisagria. For quarrelsome disposition: Calcarea, Aconite, Chamomilla, Ignatia, Lycopodium, Coffea, Aurum, Nux vom., Alumina. For malice: Belladonna, Lycopodium, Stramonium, Verat- rum, Hyoscyamus, Nux vom. For jealousy: Hyoscyamus, Lachesis, Pulsatilla, Gausticum, Cicuta, Baryta. For audacity: Ignatia, Aconite, Opium, Pulsatilla, Berberis. For rvindictiueness: Aurum, Agaricus, Lachesis, Anacardium. For artfulness : Nux vom., Lachesis, Chlorum, Drosera, Coca. For obstinacy: Belladonna, Sulphur, Ignatia, Silicea, Lyco- podium, Calcarea, Nitric ac. For greediness : Bryonia, Sepia, Arsenicum, Pulsatilla, Lyco- podium, Calcarea, Natrum carb. For fitful mood: Ignatia, Platina, Sulphuric ac., Aconite, Belladonna, Graphites, Zincum. For suicidal disposition: Aurum, Arsenicum, Belladonna, Antimonium crud., Pulsatilla, Nux vom., Derris pin. For disposition to kill : Stramonium, Arsenicum, Hepar, China, Lachesis. For disposition to commit acts of violence: Belladonna, Stra- monium, Hyoscyamus, Veratrum, Cocculus, Platina, Cuprum, Lycopodium. Therapeutic Indications.--See melancholia and mania for both indications and auxiliary treatment. MANIA. 243 MANIA. Syn0nyms.——Madness, Insanity, Furor Mania; Fr., Fureur, Manic Aiguéi; Ger., T obsucht, Wuth, T ollheit. Definiti0n.—Disorder of the intellect, characterized by hallucinations or delusions which impel to acts of violence. Diagnosis.-—The violence which characterizes acute mania is such as to prevent any error of diagnosis in cases of that character; but there are many varieties of simple mania, aris- ing from numerous causes, in which the excitement is not very great, nor the delusions, if any, very manifest, especially in the early stages; but they are all attended by more or less excitement, there is no gloom or depression, the conduct is more or less noisy and irrational, and, sooner or later, de- lusions, coinciding with the temper and bodily condition, manifest themselves. Moreover, the will-power is usually 1nore or less impaired, perception, reason and volition are all to a greater or less extent defective, and if any motive actuates the patient, there is such a want of correspondence between it and the act that there cannot be said to be any adequate mo- tive for it. Pathology.—The physical changes in the brain which char- acterize insanity are best seen in chronic cases, where we find degeneration of the cerebral nerve-cells, producing condensa- tion and atrophy of the gray substance, increased weight, di- minished volume and chronic inflammation, with softening. Now, although such changes are not observed to any such ex- tent in acute cases, it cannot be doubted that material altera- tions do exist in all cases of insanity, whether acute or chronic. Even with our inadequate means of demonstration, Balfour, who analyzed seven hundred post-mortems, found tissue alter- ations in ninety-one per cent. of his cases. Hence the con- census of opinion among alienists now is, that insanity is an actual morbid condition of the brain itself, and not a mere functional disturbance, as was once thought. Indeed, so evi-- dent is this truth, that the eminent physiologist, Van der Kolk, asserts that he never failed to discover pathological changes where there was abnormal mental function manifested ; as, for 244 NERVOUS THERAPEUTICS. example, where mania existed he found the cortical layer under the frontal bones darkened, more closely adherent to the pia mater, or softened. Clinical Experience.—Acute or Furious Mania.—Stramo- nium, Opium , Tarantula, Hysocyamus, Belladonna, Gelsemium, Cuprum. Suicidal Mania.—Aurum, Nux vom., Pulsatilla, Rhus tox., Belladonna, Sepia, Platina, Zincum, Carbo veg., Alumina, Mercurius, Staphisagria, China, Sulphur, Nitric ac., Arsen- ioum. Religious Mania.—-Stramonium, 'Baryta, Aurum, Crocus, Lachesis, Veratrum. Mania, with Fear.—Aconite, Opium, Veratrum. Mania, with Aversion.—Conium, Aurum, Calcarea carb., Ci- cuta, Ammonium mur. Gay Manial—Stramonium, Hyoscyamus, Belladonna, Au- rum, Platina, Crocus, Lycopodium, Veratrum, Anacardium. Apathetic Mania.—Argentum, Antimonium crud., Coca. Antagonistic States of Minol.——Phosphorus, Anacardium, Staphisagria, Sepia, Capsicum. Puerperal Mania.—Platina, Cimicifuga, Belladonna, Pulsa- tilla, Ignatia, Aurum, Hyoscyamus. Therapeutic Indications—Stramonium.—Acute mania, char- acterized by furious rage; gay mania, dances, gesticulates, laughs and sings, has paroxysms of constant talking, or breaks out into low laughter, or is in ecstasy, filled with pleasant fancies, expresses his wishes _by signs, exceedingly busy with his fancy and quite cheerful ; religious mania, kneels down, stretches his hands out with pious look, starts up from the least opposition, with wild cries and violent gestures; puerperal mania and ng/mphomania, with obscene gestures and language ; desires light and company, being afraid to go alone; very loquacious, in a prayerful, beseeching, inciploring language; face often red and bloated. 0pium.—-Furious mania, with rage, fear, distortion of face, protruding and conjested eyes, bluish redness and swelling of the lips; paroxysms of rage, with rolling on the floor and threats against his own relatives, whom he does not seem to recognize. MANIA. 245 Hyoscyamus.-—Acute and subacute mania, with or without de- lusions, where the patients are destructive, tearing up and breaking everything, and filthy in their habits; talks incessantly and does not sleep ; noisy, shouting and walking about inces- santly; wants to go naked, will wear no clothes, tears them into tatters; hallucinations, but little or no cerebral congestion ; gay mania, dances, laughs in an absent manner, makes ridiculous gesticulations like a clown, and performs funny tricks like a monkey ; religious mania, alternately ludicrous, solemn or furious, dresses in some fantastic way, as in a priest’s gown over his shirt with fur boots, wants to go to church in this guise in order to preach or officiate at mass, and ferociously at- tacks all who try to oppose him; puerperal mania, thinks she has killed her child, and that her chin has become a duck’s bill; sleepless, unwilling to remain in bed, delirious, but not violent, or else furious, with indescribable rage and horrid an- guish ; does not know her own relatives; complains of having been poisoned; complete loss of modesty, throws off the bed- clothes; hyperaesthesia of cutaneous nerves; melancholy, with muttering, starting and twitching. Belladonna.——Acute, ‘subacute and chronic mania, with conges- tion of the brain, headache, flushed face, hallucinations, intol- erance of light and noise, desire to suicide by drowning ; chronic, with occasional exhibitions of silly laughing during agreeable intervals ; unsteadiness of purpose, with almost con- stant tendency to move some part of the body, especially the hands, indisposition to converse, especially with strangers, to whom she makes determined answers; opposition excites rage and de- structive tendencies; walks hurriedly, sings, dances, laughs and waves her hands; worse in the afternoon, evenings and at the approach of the menstrual period; desire to bite, strike and run away ; gay mania, a merry craziness, with laughing and singing, tries to compose songs, and sings merry but senseless tunes, or whistles occasionally, but refuses to eat or drink, or sings or hums different airs, or smiles a long time to himself, or is disposed to sing or whistle, with frequent bursts of laugh- ter, or is wild and wantonly merry, with inclination to quarrel "without cause, or will tear off clothes, run out into the street 246 NERVOUS THERAPEUTICS. partially or wholly naked, gesticulating in a strange manner, crying, laughing, muttering and demanding foolish things; suicidal mania, with distaste for life and desire for death ; wishes some one to kill him; attempts to jump out of the window; alternating with paroxysms of fury; puerperal mania, merry but quarrelsome; strikes and bites ; starts in affright at the approach of others; tries to escape or hide ; insomnia, fear of ghosts, moaning; begs those around her to get her out of the way and kill her. Aurum.——Sleeplessness, anguish of mind, seems to have no friends; fits of anger, rashness and fury ; desperate actions and thrashing about; speaks continually in questions and is quar- relsome; great depression, with suicidal tendency; suicidal mania, great desire to commit self-destruction, seeking every opportunity to do so; excessive desire for water, with melan- choly notion that he was not intended for this world ; anxious desire to take his own life, attended with derangement and cramps in stomach and bowels; religious mania, he imagines he is irretrievably lost, with desponding shouts and screams ; puerperal mania, with preoordial anguish, driving her from place to place ; unhappy, with continual thoughts of suicide ; prays all the time; imagines she is not fit for this world ; weak memory and intellect. Nux v0m.—Obstinate and quarrelsome, increasing to violence; suicidal mania, desire for death, because ‘his agony of mind allows him no repose, because present pain and misfortune seem insupportable to him ; inclined to take his own life, with palpitation of heart and great anxiety; morose and taciturn; disposed to quarrel if disturbed; giddiness, with reeling; con,- stipation; gastric disturbances; nymphornania. Anacardium.—Sensation of being possessed of two opposing wills; is inclined to laugh when he ought to be serious, and does not incline to laugh when tempted by what is ludicrous; actions stupid and childish; rapid loss of self-reliance, memory and mental vigor; incipient dementia. Mercurills.-—Insomnia, with peevishness, irritable temper, great restlessness, apathy, sensation as if the head would burst; suicidal mania, with disgust for life, from want of courage to MANIA. 247 meet trials and mortification, or desire for death, from an in- supportable dislike for every person and thing, even those which are most loved. Aconite.——Acute mania, attended with fear, despondency and apprehensions of future calamity; anxious lamentations ac- companied by disheartening apprehensions; anxiety, attended with heat of the face and head, palpitation of the heart and coldness of the extremities; apprehensions of approaching death; puerperal mania, with great fear of death; ailments from fright or anger; fear of strangers, of not getting up; inconsol.- able anxiety; reproaching others for mere trifles. Gelsemium.—/lcute mania, attended with cerebral congestion; head hot, face flushed, eyes red and protruding; surface and extremities cold, or cold and hot alternately; wild demeanor; puerperal mania, with great depression of spirits, pain in the back of the head and neck, congestion of the base of the brain, dilated pupils, blur before the eyes, lochia arrested or very scanty. Arsenicum.—Restless, sleepless and in constant mental agony; poor appetite, eats only under compulsion; pain in occiput, ' running up over the head to forehead; eyes have a blur over them so that she can scarcely see; says she cannot control her mind; tongue bright red and seamed; hands and feet cold; bowels constipated; suicidal mania, attempts to strangle herself with a string at night, though constantly watched. Crocus.—Fickle, changeable disposition; cheerfulness, mirth, joy, sadness, despair all follow each other in rapid succession; religious mania, gloomy, sad mood, with great anxiety about the future. Sepia.——Imagines things he does not want to imagine; uses wrong expressions, knowing them to be wrong; proposes to him- self things contrary to his intentions; is in contradiction with himself; has paroxysms of laughter and weeping in alterna- tion, without either of them resulting from a corresponding frame of mind; gastric disturbances, with constipation. Cuprum.-—Acute, furious mania, attended with full, quick pulse, red and inflamed eyes, wild looks, incoherent speech and rage, every paroxysm terminating in perspiration. 248 NERVOUS THERAPEUTICS. Tarantula.—Restlessness of the hands and legs, constant movement, cannot remain in one place; great and constant heat about the epigastrium ; disposition to joke and laugh and play tricks, with impulsive movements; sudden, foxlike and . destructive efforts, requiring the utmost vigilance to prevent damage, followed by laughter and then apologies; all the symp- toms relieved by music; screams, sings, bites, throws things violently about, springs out of bed, destroying whatever she can get hold of; sleeps two days, then awakes with screaming; soils the bed with urine. Compare, also, Cimicifuga, Veratrum, Platina, Ignatia, Can- nabis ind., Phosphoric ac., Iodium, Pulsatilla, Zincum, Staph- isagria, Alumina, Nitric ac., China, Rhus tox. Auxiliary Treatment.——The patient should, if possible, be removed from his own home to a sanitarium, or place where the surroundings are such as to lead him to forget his malady, or at least to so occupy his mind by /new objects as to divert it from the old, and not to call up, by sight or otherwise, any of those ideas or objects which occasioned, or are liable to renew or aggravate, the malady. Moral rather than physical restraint should be employed, the patient being at all times encouraged to exercise his own self-control. Hence his attendant should be a person of great discretion, self-control, kindness and watchfulness, the latter being exercised in such a manner as not to attract the patient’s attention. Everything about the patient should be made to appear as cheerful as the circum- stances of the case will admit. Thus the room ordinarily occupied should be light, well ventilated and ornamented with pictures, flowers and everything calculated to gratify the inno- cent tastes of the patient. Employment, recreation and vari- ous forms of amusement, suited to the capacity of the patient, should be provided for him, both as stimulants in the renewal of health and to prevent the mind reacting on itself. As the patient improves, his attention should be gradually, but cau- tiously, directed to former objects and associations, until all danger of shock or relapse has passed. The diet should always be generous and such as is suited to an anaemic or debilitated state of the system. Many a threatened attack of mania may DIPSOMANIA, 249 be prevented by the timely administration of a warm bath, stimulants and a generous diet. DIPSOMANIA. Syn0nyms.—Oinomania; Fr., Manic Ebrieuse, Manic Crapu- lease ; Ger, T ranlcsacht. Definition.—A morbid condition of the nervous system, characterized by an inordinate craving, generally periodic, for alcoholic stimulants. Diagnosis.—-This disease is liable to be confounded with habitual drunkenness. In the former, however, the craving exists independent of external circumstances of temptation, while in the latter it consists mainly in a desire to maintain a condition of stimulation to which the patient has become accustomed. Pathology.-—This form of insanity, like that of others, can generally be traced in the family history. The pathological changes are marked in all cases, but they vary greatly, accord- ing to the stage of the disease. There is always more or less atrophy of the cortical substance, with degeneration of the ganglion cells. As the tendency is to dementia, very few organs of the body escape disease, of which fatty degeneration of the heart, liver, kidneys and voluntary muscles is the most constant. Permanent intellectual and moral degradation characterizes the disease, and if the patient lives long enough he is almost certain, sooner or later, to become hopelessly demented. Clinical Experience. — This is not very encouraging. Sulphuric ac., Tartar emet., Angelica, China, Arsenicum, Nux vom., Pulsatilla, and especially Strychm'a gr. of the nitrate, three times a day for six weeks), have helped and sometimes cured individual cases; but unless the dipsomaniac can be secluded in an asylum long enough to work a change in the nutrition of the brain, the morbid tendency is not likely to be eradicated by any treatment, however judicious or prolonged it may be. Therapeutic Indications.—See the following section, mam'a a potu. 17 250 NERVQUS THERAPEUTICS. MANIA A POTU. Synqnyms.—De1irium Tremens, Trembling Delirium; Fr., Délire Ebrieuse, Délire Crapuleuse; Ger, Zitterwahnsinn. Definition.—A form of delirium, characterized by great mental agitation and muscular tremor, peculiar to persons ad- dicted to the immoderate use of alcoholic stimulants. Diagnosis.——It is scarcely possible to mistake the disease for any other, as, in addition to the history of the case, we have the characteristic symptoms, such as complete insomnia, tremor of the voluntary muscles, and, above all, the mental symptoms, such as imaginary fears, visions of snakes, insects, monsters, etc. There are two forms, the acute (mania a potu proper), without trembling, and the chronic (delirium tremens proper), with trembling, after which the disorder is named. Patho1ogy.—The most recent observations and experiments conclusively prove that, contrary to the old notion, the phe- nomena of delirium tremens do not arise from the sudden withdrawal of an accustomed stimulus, but from the effects of its accumulation in the system, just as mercurial tremors arise from the inhalation of mercurial fumes. After a time, depend- , ing on the susceptibility of the drinker, the system becomes, so to speak, saturated with alcohol, and after that no more can be taken without producing the trembling and other nervous symptoms peculiar to the disease. No characteristic morbid changes are observed after death in the acute form; in the chronic they resemble, when present, those of dipsomania, which see. Clinical EXperience.—Belladonna, Stramonium, Hyoscyamus, Opium, Cimicifuga, Cannabis ind., Capsicum and Tartar emet. are all effective remedies, while Arsenicum, Agaricus, Nux vom., Digi- talis, Scutellaria and Cypripedium are also of much benefit in particular cases. Therapeutic Indications. —- Bel1adonna.- Delirium, with visions of rats, mice, etc. ; imagines he sees water running over the table and window panes; tries to extract one of his teeth; smiles and stammers; dry feeling in the throat, with difiiculty MANIA A POTU. 251 of swallowing; fever, with thirst; cerebral congestion; restless, anxious and unsteady in his walk and actions; trembling of the hands. Stramonium.——-Delirium, with frightful visions and hallucina- tions; sees animals and strangers attacking him from all sides; hides himself, or tries to escape; hears imaginary voices; face red and swollen; eyes glistening and staring; manner hurried and fitful; limbs in a constant tremor; talks absurdly, laughs, starts at every sound and movement and looks greatly fright- ened; complete insomnia. Hyoscyamus.—-Starts and trembles as if by fright; wants to hide from the light and from company; fears persecution; con- stantly tossing about at night, cannot sleep; derangement of the stomach, with loss of appetite; disposed to laugh at his own fears, yet trembles in every limb. 0pium.—Stupor, from which the patient starts in great fright or mutters in his sleep, talking deliriously; dreams of animals glaring at him with their fiery-red eyes; trembles, looks fright- ened and tries to escape; becomes comatose, with loud, snoring respiration, dilated pupils and half-closed eyes; reduced vital power. Cimicifuga.-—Complete insomnia; imagines he sees rats, mice, lizards and other strange objects; talks incessantly, changing from one subject to another without any good reason; pulse full and quick; eyes wild and staring; stomach disordered; cross and taciturn; tremor scarcely visible, but apparent to the touch; occipital headache. Cannabis ind.——Illusions of a spectral character and of strange sounds at night; wakes before midnight overcome with fright; imagines he is going to be choked; all objects appear double their natural size; talks incoherently, stammering and stut- tering; everything, even his own hand, appears monstrously large. Capsicum.—Prostration extreme, tremor excessive, delirium bland; thinks the ceiling is about to fall and crush him, caus- ing him to jump from the bed as quickly as his weak condition would allow; tongue coated, pulse small and irregular, skin moist, forehead constantly bedewed with a cold,-clammy sweat; 252 NERVOUS THERAPEUTICS. voice‘ feeble, husky and tremulous; complete insomnia for three successive nights. Antimonium tart.—Fearful delirium ; constantly throwing pillows at imaginary demons; eyes red and injected; pulse quick and irritable; has neither eaten nor slept for more than a week; gastric derangement from drinking beer; low states of the system, with profuse, cool sweats. Arsenicum.—Muscular tremors, with great prostration; fear, with great anguish and sweat, dread of ghosts, of thieves or of death, and especially of vermin crawling over the bed or over the hands; gastritis. Gelsemium.—-Delirium, with great nervous excitement, head- ache, fear and wakefulness; had not slept for ten nights; kicked off the footboard struggling with his attendant, con- stantly calling for more whisky; produced sleep after morphia had failed. Compare, also, Nux vom., Gratiola, Coffea, Kali brom., Ran- unculus bulb., Nux mosch, Digitalis, Calcarea. Auxiliary Treatment.—Confinement always irritates the patient and increases his fears; no more restraint, therefore, should be placed upon his movements than is necessary to pre- vent accidents. The chief danger to be guarded against is ex- haustion; hence care should be taken to provide for the nutri- tion of the impoverished brain and nerve-centres, by the free administration of food which can be easily digested and assimilated. Beef-tea, raw eggs and milk or warm coffee, coca, warm milk and egg-emulsion will usually give satisfactory results. Aitken recommends Cayenne pepper. The stimulus of such a spice, he says, given in soup, on the atonic stomach, will have a favorable influence on absorption. Lilienthal ad- vises us to keep our patients on an exclusive milk diet, as it antidotes alcohol and sometimes causes a disgust for it. DEMENTIA. Synonyms.—-Mental Decay; Fr., Démence; Ger, Bliidsinn. Definition.—A gradual decay of the mental faculties. Diagnosis.-Acute primary dementia, which does not come DEMENTIA. 253 under the above definition, sets in rapidly without any preced- ing disorder, affects only young people, usually girls, and is amenable to treatment. Chronic primary dementia, though sometimes a sequel of the acute, usually comes on gradually, and when not caused by disease of the brain generally results from years of hard drinking, its chief symptom being loss of memory. Secondary dementia, which is the form to which the term is usually applied, is a sequel to previous mental disorder, such as melancholia and mania. These distinctions are sufli- cient for diagnostic purposes. Path0l0gy.—The pathological condition, in most cases of dementia, is one of diffuse interstitial inflammation of the great, nervous centres, which results eventually in destruction of ganglion cells and atrophy of the nervous structures. Indeed, the degree of imbecility is generally pretty accurately measured by the amount of atrophy and destruction of ganglion cells Which the cerebral nerve-centres have undergone. Treatment.—On this point little can be said. The same > careful tending and nursing are required as in infancy, the weakness and helplessness being equally great. Although, with the exception of the acute primary form, a cure is not to be expected, medicines are often of great utility. Such remedies as Arsenicum, Acidwm nit. and phosph, Carbo veg., China, Digitalis, Phosphorus, Nux vom., Pydophyllin, etc., are frequently required to render the patient more comfortable and to prolong his life; while during the earlier stages the decay of the mental faculties may be greatly retarded, and in some cases arrested, by Anacardium, Ignatia, Phosphoric ac., etc., the selection being determined, as in all other cases, in accord- ance with the symptoms presented by the patient at the time of prescribing.* * From the author’s work on Nervous Diseases, p. 379. INDEX. SEo'rIoN I.—DIsEAsEs. Abnormal growths, cerebral, 48 . —- —- spinal, 111 Abscess, cerebral, 32, 35 Acute ascending paralysis, 94 — hydrocephalus, 67 Adults, spinal paralysis of, 95 a Alkaline solvents, 29 Amyotrophic lateral sclerosis, 102 — paralysis, 101 Anaemia, cerebral, 9 — antero-lateral columns, 78 — cerebro-spinal, 117 — general, 117 — posterior columns, 81 — posterior spinal, 81 — spinal, 78 Anapeiretic paralysis, 188 Anaesthesia, 27, 192 —— peripheral, 192 Antero-lateral columns, anaemia of, 78 Anterior horns, inflam. of, 95 Angina pectoris, 200 Antero-spmal paralysis of infancy, 97 Aphasia, 37 Aphemia, 37 Aphonia, paralytic, 181 Apoplectic stroke, 21 Apoplexy, cerebral, 21 — spinal, 84 Apoplexia sanguinia, 21 Arachnitis, cerebral, 60 —- spinal, 85 —- traumatic 60 Artificial dehvery in puerperal convulsions, 137 Ascending and descending degenerations, 162 Asthenic paralysis, 185 Ataxia, locomotor, 107 Atrophia cerebri, 40 — musculorum lipomatosa, 98 Atrophic spinal paralysis, 95 Atrophy, cerebra , 42 - facial, 194 — Cruveilh.ier’s, 101 — progressive muscular, 101 facial, 191 Athetosis, 44, 56 Bandages in sciatica, 180 Basedow’s disease, 198 Baths, salt, 26, 185 —- sea, 168, 170 -— shower, 208 — steam, 152 —— sun, 209 - vapor, 200 — warm, 111, 147, 190, 240 Bowels, neuralgia of, 211 Brain, anaemia of, 9 —— arachnoid, inflam. of, 60 — atrophy of, 40 -— concussion of‘, 50 — congestion of, 14 — dropsy of, 73 Brain, haemorrhage of, 21 — hyperzemia of, 14 — hypertrophy of, 39 —- p1a mater, inflam. of, 60, 62 — softening of, 34 — sup urative inflam. of, 32 — syp ' itic disease of, 45 — tumors of, 48 — water on, 73 Brain-fag, 9, 117 Breast-pang, 200 Bronchocele, exophthalmic, 198 Brown-Sequard on cerebral syphilis, 46 —— — “vitalizin fluid,” 122 Bumpf's treat. 0 locomotor ataxia, 111 Bulbar paralysis, 99 Canine madness, 148 Cardiac neuralgia, 200 Cardialgia, 204 Carus, 229 — catalepsia, 161 Catalepsy, 161 Cauterization, prophylactic, 151 Central myelitis, 144 Cephalal a, 195, 214 — perio ‘ca, 195 Cerebral anaemia, 9 — abscess, 32 — apoplexy, 21 —— arachnitis, 60 —— atrophy, 40 — concussion, 50 -— congestion, 14 -— embolism, 30 — haemorrhage, 21 — hyperaemia, 14 -— hypaemia, 9 — hypertrophy, 39 — leptomeningitis, traumatic, 61 meningeal haemorrhage, 59 meningitis, chronic, 71 —- granular, 67 -- simple acute, 62 —- tubercular, 67 pachymeningitis, acute, 58 —- chronic 59 -- external, 58 -— internal, 59 —— secondary, 58 — traumatic, 58 paralysis, 54 -— infantile, 56 sclerosis, diffused, 40 —— multiple, 42 softening, 34 syphiloma, 71 syphilis, 45, 71 t ombosis, 27 —- tumors, 48 Cerebro-spinal hyperwmia, 116 anaemia, 117 meningitis, 123 fever, 123 Illllllllllllllllll (25 256 INDEX. .000. 0''’ 0.,‘ on... .I.. Cerebro-s inal sclerosis, 162 Differential cerebral concussion, 50 Cerebras enia, 10, 117 — — embolism, 27 Cerebritis, 32 — — epilepsie, 157 Coccygodynia, 175 —— —- hyperaemia, 9 Cold applications, 20, 54, 57, 84, 85, 175, 180, — -- paralysis, infantile, 59 190 — - thrombosis, 27 — douche, 54, 175 — -- paralysis, cerebral, 56 Childhood, essential paralysis of, 97 -— — — spmal, 56 Chorea, 152 -- — — infantile, 97 — minor, 152 -— hysteria, 118, 157 — Sancti Viti, 152 — progressive muscular atrophy, 97 Chronic cerebral meningitis, 71 — neurasthenia, 117, 118 -- inflam. of brain, 32 — peripheral neuritis, 96 — hydroce halus, 73 — poliomyelitis, 96 Columns 0 Burdach, sclerosis of, 107 — simple meningitis, basilar, 63 Coma somnolentum, 229 -— —- — tubercular, 67 Compression, in neural ' , 168, 170 -— typhoid fever, 67 — in chronic hydrocep lus, 75 Diffused cerebral sclerosis, 40 — in hystero-epilepsy, 160 Diplegia facialis 184 Commotio medulla spinalis, 112 Diphtheritic paralysis, 185 -— cerebralis, 50 Dipsomania, 249 Congestion, cerebral, 14 Disseminated sclerosis, cerebro-spinal, 162 — cerebro-spinal, 116 -- — cerebral, 42 — spinal, 76 -— — multilocular, 103 Concussion, cerebral, 50 —- — spinal 103 - spinal, 112 Dizziness, zés Convulsions, cholaemic, 138 Dog-madness, 148 — infantile, 129 Douche, cold, 54, 98, 115 — of pregnancy and parturition, 134 — salt-water, 115 — of the new-born, 134 - spray, 90 — postnatal, 133 Dowse, Dr., on cerebral syphilis, 46 — puerperal, 134 Dro )sy of the brain, 73 — toxaemic, 138 Due enne’s disease, 99 — urmmic, 134, 138 Convulsive tic, 187 Cretinism, mucoid, 199 Eclampsia gravidarum et parturientium, 134 Croup spasmodic, 189 — mfantum, 129 Cruve1lhier’s atrophy, 101 — neonatorum, 134 Cutaneous anaesthesia, 192 — toxica, 138 Electricity in angina pectoris, 204 — athetosis, 45 Debility, nervous, 117 -- bulbar paralysis, 100 Degeneration, cerebral, diffused, 40 catalepsy, 161 — — multiple, 42 cerebral anaemia, 13 — spinal, primary, 104 — —— atrophy, 41 — — secondary 206 — -— haemorrhage, 44 — cerebro-spinal, 160 — -— hyperaemia, 20 Delirium tremens, 250 — -— sclerosis, 44 \ Dementia, 163, 252 — — tumors, 49 — paralytica, 163 — chorea, 156 Diet in athetosis, 45 coccygodynia, 177 — anaemia, 13 diphtheritic paralysis, 185 — bulbar paralysis 101 -— facial paralysis, 184 — meningitis, cerebral, 60 -- glossoplegia, 187 — — cerebro-spinal, 129 - hydrophobia, 152 — convulsions, toxic, 139 - hysteralgia, 210 — cerebral thrombosis, 29 — locomotor ataxia, 111 — delirium tremens, 252 — muscular atrophy, 96 - epilepsy 144, 157 — neuralgia, 168, 170, 173 —- encephalitis, 34 — neurasthenia, 121 —— ext. pachymeningitis 59 — peripheral anmsthesia, 194 — haemorrhage, cerebra , 26 — paralytic aphonia, 181 -— hemicrania. 198 -— sciatica, 180 — insomnia, 236 - spinal hyperaemia, 78 — mania, 248 -- -— irritation, 84 — melancholia, 240 -— - meningitis, 88 — neuralgia, 168, 170, 181 -— —- paralysis of adults, 97 — neurasthenia, 122 -- — - infantile, 97 -— sciatica, 181 -— — pseudo-hypertrophic, 99 — spinal anaemia, 80 —- — sclerosis, 104 — -— meningitis, chronic, 88 Electric brush, 111, 194 — tubercular meningitis, 71 Electro-cautery, 88 — tetanus, 146 Electro-massage, 97 — the Weir Mitchell, 122 Embohc dust 31 Differential diagnosis, in Embolism, solvents in, 29 — anaemia, cerebral, 9 Emotional insanity, a41 — — general, 117, 118 Encephalitis, 32 -— angina pectoris, 201 Enemata, 168 — cerebral compression, 50 Entasia tetanus, 144 g 0 0... 2 : .0’. ' : INDEX. 257 Enterodynia, 211 Enteralgia, 211 Epidemlc meningitis, 123 Epilepsia, epilepsis, 139 Epileptiform hysteria, 159 Epilepsy 139 Essential paralysis of childhood, 97 Ether-spray,180, 204 Exhaustion, nervous, 117 -— spinal, 78 Exophthalmic goitre, 198 Exercise, 20, 27, 115, 185, 190, 240 External cerebral pachymeningitis, 58 Extirpation of the coccyx, 177 Facial atrophy, 191 — neuralgia, 171 -— paralysis, 184 -— spasm, 187 ' Falling-smkness, 139 Femero-popliteal neural ‘a, 177 Functional paralysis of t e cord, 78 Furor mania, 243 Galvanism in -— athetosis, 45 — cerebral atrophy, 41 — — hsemorrhage, 26 — — hyperaemia, 20 — — sclerosis, 44 — -— tumors, 49 — exophthalmic goitre, 199 — facial aralysis, 184 — astra ‘a 208 — ydrop 0 ia, 150 -— locomotor ataxia, 111 — infantile spinal paralysis, 98 — neuralgia, 173, 180 — paralytic aphonia, 184 - progressive muscular atrophy, 102 — sciatica, 180 — sclerosis, 104 — spinal concussion, 115 -— — irritation, 84 — — menin 't1s, chronic, 88 — vertigo, 2 9 —- writer’s cramp, 188 — wry-neck, 188 Gastral ‘a, 204 Gastro ynia, 204 General paralysis, 163 paresis, 163 Glossoplegia, 186 Glosso-labio-laryngeal paralysis, 99 Glottis, spasm of, 189 Giddiness, 223 Goitre exophthalmic, 198 Granular cerebral meningitis, 67 Grave’s disease, 198 Gumma syphiliticum cerebri, 45 Gussenbauer on trifacial neuralgia, 171 Gymnastic exercise, 15, 188 0 Haematoma clurae matris, 59 Haematomyelia, 84 Haematorrhagia medulla spinalis, 84 Haemorrhagic pachymeningitis, 59 Haemorrhage, cerebral, 21 — meningeal, 59 —- spinal, 84 Heartburn, 204 Heat-stroke, 52 Hammond’s athetosis, 44 Headache, 195, 214 Hemicrania, 195 Heat, artificial, in — -’— cerebral hyperaemia, 2) —- — paralysis, 57 — — meningitis, 67 — -— softening, 36 -— cerebro-spinal meningitis, 129 — enteral ‘a, 213 — hystera gia, 210 — mastodynia, 175 — neuralgia, 168, 170 — neuritis, 166 — ovaral a, 208 —- spinal yperaemia, 78 —— -— irritation, 84 — tetanus, 145 Hemiplegia, 54 -— cerebmlis spastica, 56 Hot douche, 78 Hydrocephalus, acute, 67 — acutus sine tuberculosis, 62 — chronic 73 — internal, 67- Hydrops capitis, 73 Hydrophobia, 148 Hyperaesthesia plexus cardica, 200 Hypertrophia cerebri, 39 Hypo, 240 Hypochondriasis, 240 Hypoglossal nerve, paralysis of, 186 Hyperaemia, cerebra , 14 — cerebro-spinal, 116 — spinal, 76 Hysteria, 118, 156 — cataleptica, 161 -— epileptica, 157 Hysteric fit, 156 Hysterics, 156 Hystero-epilepsy, 159 Hysteralgm, 210 Hyperplasia, cerebral neuroglia, 39 Hypertrophy, cerebral, 39 Ice and ice-water applications, 54, 57, 66, 83, 88, 115, 129, 147 152, 160, 166. Idiopathic cerebral leptomeningitis, 62 — latent spinal sclerosis, 104 — softening of the cord, 90 Impulsive insanity, 241 Infantile cerebral paralysis, 56 - convulsions, 129 — spinal paralysis 97 Inflammation of the anterior horns, 95 — lateral columns, 102 — nerve 166 — spina cord, 88 Inflammatory softening of the cord, 88 Inhibitory paralysis, 78 Inanition, convulsions from, 138 Insane, paralysis of, 163 Insanity, affective, 241 — common, 243 — emotional, 241 — impulsive, 241 — intellectual, 243 — moral, 241 Insolation, 52 Insomnia, 232 Insolatio, 52 Internal cerebral pachymeningitis, 59 Insular spinal sclerosis, 103 Irritable uterus, 210 Irritation, spinal, 84 Ischias, 177 Karl Pauli on locomotor ataxia, 111 Labio-glosso-laryngeal paralysis, 99 258 INDEX. '|||||||||| Lan ’s paralysis, 94 Later co umns, inflam. of, 102 —- sclerosis, idiopathic, 104 — —— amyotrophic, 102 —- — primary, 104 Laryngismus stridulus, 189 Larynx, paralysis of, 181 — spasm of, 189 Leptomeningitis, cerebral, 61, 62 — infantile, 62 — idiopathic, 62 — spinal, 85 —- traumatic, 61 — tubercular, 67 Lethargia, 229 Lethargy, 229 Lipomatosis musculorum luxurians, 98 Local anaesthesia, 192 Lockjaw, 144 Locomotor ataxia, 107 Lyssa, 148 Madness, 148, 243 Malum hystericum, 156 Mammae, neuralgia of, 174 Massage, 13, 26, 97, 120, 139, 184, 194, 240 — electro 9 Melancholia, 237 Mania, 243 —- a potu, 250 Mastal ' , 174 Masto ynia, 174 Megrim, 196 Meningeal haemorrhage, cerebral, 59 -— tumors, spinal, 112 Menin es, spinal, inflam. of, 85 — cere ral, inflam. of, 60, 62 Menin 'tis, basilar, 62, 71 cere ml, 60, 62, 71 cerebro-spinal, 121 chronic, 71 convexital, 71 epidemic, 121 spinal, 85 simple acute 62 subarachnoid, 60 syphilitic, 71 tubercular, 62, 67 Mental decay, 252 Metallotherapy in hystero-epilepsy, 160 Mimetic spasm, 187 Moral insanity, 241 — treatment, 159, 240, 248 Morbus attonitus, 161 — hypochondriacus, 240 — ma us, major, daemonius, divinus, deificus, unaticus etc., 139 Mollities medulla: spinalis, 90 Mucoid cretinism, 199 Muscular atrophy, 96, 101 — — progressive, 96 —— paralysis, progressive, 101 —- seudo-hypertrophic, 98 Mu tilocular sclerosis, disseminated, 103 Multiple sclerosis, cerebro-spinal, 162 -— — cerebral, 42 — — spinal, 103 Myelitis, acute, 88 — bulbi, 99 — central, 144 Myelasthenia, 78, 117 Myelomalasia, 90 Myopathic paralysis, 101 Myxoedema, 199 Nerves, inflam. of, 166 Nerve-stretchin , 73, 110, 146, 166, 168, 170, 173 Nervous exhaustion, 117 -— headache, 195 -— pain, 167 Neuralgia, in general, 167 —— of the bowels, 211 — cardiac, 200 — of the coccyx, 175 — femero-po liteal, 177 — intercos , 177 — ischiatic, 177 — of the mammae, 174 — meseraic, 211 — ovarian, 208 —— phrenic 200 -— spinal, 1 -— of the stomach, 204 — trifacial, 171 — uterine, 210 Neural anaesthesia, 192 Neuritis, 166 , Neurod nia, 167 Neurog ia, hyperplasia of, 39 Neurasthenia, 9, 78, 117 — cerebralis, 9 ' — spinalis, 78 117 Neurotic faci atrophy, 191 Nutrition, 168, 170 Oinomania, 249 Ovaralgia, 208 Ovarian irritation, 208 —- neuralgia, 208 Ovaries, pain in, 208 Ord’s cretinoid affection, 199 Pain, neuralgic, 167 — ovarian, 208 Paralytic aphonia 181 Paralysis, cerebral, 54 — acute ascending, 94 — — progressive, 94 — antero-spinal, of infancy, 97 — anapeiretic, 188 — agitans, 164 — atrophica, 101 — ascendens acuta, 94 — amyotrophic, 101 — asthenic, 185 — Bell’s, 184 — Cruveilhier’s, 101 — diphtheritic, 185 —- facial, 184 — functional 78 — general, of the insane, 163 —- losso-labio-laryngeal, 99 — istrionic, 183 —- infantile, 97 - inhibitory, 78 — Landry’s, 94 — myo athic, 101 — Of a ults, 95 — of the hypoglossal nerve, 186 —- of the larynx, 99, 181 —- of the pharynx, 99, 181 —- of the portio dura 183 — of the tongue, 186 —- progressive bulbar, 99 — pseudo-hypertrophic, 98 — reflex, 93 — spasmodic, 104 —- spinalis spastica, 104 — spinal, 92-107 — — of adults, 95 — toxic, 93 Palsy, common cerebral, 54 —- shaking, 164 — Schrivener’s, 188 - spinal, 78, 92 mnnx. 259 Paralytic aphonia, 181 Paraplegia, 92 -— reflex, 78 Paraplexia, 92 Parr’s treat., Writer’s cramp, 188 Pasteur on hydrophobia, 149 Pachymeningitis, acute cerebral, 58 -— chronic 59 —- external, 58 -- haemorrhagic, 59 — internal, 59 — secondary, 58 — spinal, 85 -- traumatic, 58 Peripheral anaesthesia, 192 — neuritis, 96 Pervigilium, 232 Pharynx, paralysis of, 99, 181 Pia mater, cerebral, inflam. of, 62 Phrenic nerve, neuralgia of, 200 Poliencephalitis acuta, 56 Poliomyelitis anterior, 95 Polymyositis, progressive, 101 Posterior spinal anaemia, 81 — — sclerosis, 107 Post-diphtheritic Paralysis, 185 Postnatal convulsions, 133 Primary sclerosis, lateral, 104 — — cerebral, 42 — —-— spinal, 104 -— softening, spinal, 90 Progressive bulbar paralysis, 99 — facial atrophy, 191 - — hemiatrophy, 191 _ -- locomotor ataxia, 107 — muscular atrophy, 101 —- polymyositis 101 Prophylaxis in hydrophobia, 151 Prosopalgia, 171 Pseudo-hypertrophic spinal paralysis, 98 Puerpera convulsions, 134 Pyzemia, in cerebral pachymeningitis, 58 Babies 148 Rachi gia, 81 Reflex paraplegia, 78, 93 — para ysis spinalis, 78 Rest, in cerebral thrombosis, 29 hemicrania, 198 melancholia, 240 neurasthenia, 122 spinal haemorrhage, 85 — irritation, 84 -— concussion, 115 writer’s cramp, 188 Restraint in delirium tremens, 252 —- mania, 250 Salt-bath, in cerebral anaemia, 13 —- hmmorrhage, 28 St. Guy’s dance, 152 —- J ohn’s dance, 150 — Vitus’s dance, 150 Sciatica, 17 7 Schrivener’s palsy, 188 Sclerosis, cerebral, 41, 42 -— diffused, 41 disseminated, 42 idio athic, 42 insu ar 42 multiple, 42 — pnmary, 42 columns of Burdach, 107 spinal, 103, 104, 106 —- amyotrophic lateral, 102 -— glrsiénary, 104 ' eminated, 103 — — multiple, 103 lllllllll Sclerosis, spinal, secondary, 106 — cerebro-spinal, 162, 165 - — disseminated, 162 — - secondary, 162 Sea-bathing in neuralgia, 168, 170 —'cerebra1 anaemia 13 Secondary spinal sclerosis, 106 —— cerebro-spinal sclerosis, 162 Shaking palsy, 164 Shower-bath, in gastralgia, 208 Sick-headache, 195 Simple acute cerebral meningitis, 62 Sleeplessness, 232 Softenin , cerebral, 34 — spina , 90 Somnolentia, 229 Somnolency, 229 Sopor, 229 Spasmodic croup, 189 — spinal paralysis, 104 Spasm, facial, 187 -- laryngeal, 189 -— mimetic, 187 —— of the glottis, 189 — —- mastoid muscle, 187 — with rigidity, 144 Speech loss of, 37 Spott fever, 123 Spinal anaemia, 78, 81 — apoplexy, 84 — arachnitis, 85 —— concussion, 112 — congestion, 76 — exhaustion, 78 — haemorrhage, 84 -— hyperzemia, 76 — inflammation, 88 — irritation, 81 —- leptomemngitis, 85 — meningitis, 85 - neuralgia, 81 -— pachymeningitis, 85 — paralysis, 78, 92 — — of adults, 95 — -— atrophic, 95 — —- functional, 78 — -— infantile, 97 —- -— simple, 92 — —- spasmodic, 104 —— —— pseudo-hypertrophic, 98 -— sclerosis, disseminated, 103 — -— multiple, 103 — -- primary, 104 — -— posterior, 107 — -- secondary, 106 —— tumors, 112 Spinal cord, anaemia of, 78, 81 —- concussion of 112 — hyperaemia o , 76 —- inflam. of, 88 — inflammatory softening of, 88 — non-inflammatory softening of, 90. - paralysis of, 78 — sclerosis of, 103, 104, 160 Spleen, 240 Spotted fever, 123 Steam-bath, in hydrophobia, 151 Sternalgia, 200 Sternodynia, 200 Sternocardia, 200 Stomach, neuralgia of, 204 Stupor, 229 Subarachnoid meningitis, 61 Sun-bath, in ovaralgia, 209 Sunstroke, 52 Sus ension, in locomotor ataxia, 111 Syp ' ‘s, cerebral, 45 Syphiloma, 45 Syncope anginosa, 200 260 INDEX. Swimming of the head, 223 Syphilitic meningitis, chronic, 71 Tabes dorsalis, 107 Tapping, in chronic hydrocephalus, 75 Tetanus, 144 Thermic fever, 52 Thrombosis, cerebral, 27 —- solvents in, 29 Tongue paralysis of, 186 Tortico ‘s, 187 Toxaemic convulsions, 138 Traumatic cerebral arachnitis, 60 —- — leptomeningitis, 61 — — pachymeningitis, 58 Trembling delirium, 250 Tremors, s inal, 111 Trigemina. neuralgia, 171 Trismus, 144 — nascentium, 134 Tubercular cerebral leptomeningitis, 67 — —— meningitis, 67 Tumors, cerebral, 48 -— spinal, 112 SECTION II.-REMEDIES. Unilateral facial atrophy, 191 Uraemic convulsions, 133, 136 Uterine colic, 210 — neuralgia, 210 Vapor baths, in myxoedema, 200 Vapors, 156 Vertigo, 223 Wakefulness, 232 Warm baths, in insomnia, 236 — mania, 250 — melancholia, 240 —- spasm of glottis, 190 -— tetanus, 145 Wasting palsy 101 Water on the brain, 73 Weir Mitchell treat. in neurasthenia, 122 — spinal irritation, 84 White softening, spinal, 90 Womb, neuralgia of, 210 Writer’s cramp, 188 Wry-neck, 187 Abrotanum in treatment of cerebral soften- ing 3 Acidum tluor. in coccygodynia, 176 Aconite in treat. of acute myelitis, 89 — —- angina ectoris, 203 — —- cerebra haemorrhage, 23 -— — —- hyperaemia, 16 —- -— —— meningitis, 64 — —— cerebro-spinal meningitis, 125 — — facial paralysis, 184 -— headache, 216 — infantile convulsions, 130 -— insomnia, 234 — mania 247 — mastodynia, 175 — neural ‘a, 168, 172 —— spinal yperaemia, 77 — -— meningitis, 86 —— sunstroke 53 -— -— vertigo, 2 9 Eculus hip., in treat. of locomotor ataxia, 110 Ethusa in treat. of cerebral meningitis, 66 — — cerebro-spinal meningitis, 128 — —— chronic hydrocephalus, 74 Agaricus in treat. of angina pectoris, 304 — — cerebro-spinal meningitis, 128 — — chorea 153 —- — spinal hyperaemia, 77 Agnus cast. in treat. of melancholia, 239 Alumina in treat. of enteralgia, 212 —— -— headache, 220 — -— locomotor ataxia, 108 — — spinal anaemia, 80 Allium cepa in treat. of headache, 219 Aluminum in ascending paralysis, 94 Ambra gris. in melancholia, 239 Ammon. picr. in neuralgia, 168 —- brom. in ovaralgia, 209 Amyl nit. in treat. of angina pectoris, 202 — — cerebral hyperaemia, 16 _ — -— hemicrania, 197 — — melancholia, 239 — — sunstroke, 53 — — vertigo, 229 Anacardium in treat. of cerebral meningitis, 66 — - headache, 216 — - mania, 246 Angustura in treat. of acute myelitis, 90 Angustura in treat. of locomotor ataxia, 110 — -— myelitis, 89 —— — tetanus, 147 Antimonium crud. in treat. of headache, 222 —— — sunstroke, 50 Antimo. tart. in treat. of delirium tremens, 252 — — diphtheritic paralysis, 184 Apis mel. in cerebral hyperaemia, 17 — cerebro-spinal meningitis, 125 — — hydrocephalus, 74 — -— menin'gitis, 65, 69 —- ovaralgia, 209 Apocynum can. in treat. of chronic hydro- cephalus, 73 Apomorphia in vertigo, 226 Aranea diad. in neuralgia, 170 Artemesia vulg. in tubercular meningitis, 69 Argentum nit. in treat of — — cerebro-spinal meningitis, 127 — — epilepsy, 142 —— — astral a, 206 — — eadac e, 222 — —— locomotor ataxia, 109 — -— multiple cerebral sclerosis 43 — -- pseudo-hypertrophic paralysis, 100 — -— neuralgia, 173 — —- spinal hyperaemia, 77 — — vertigo, 227 Arnica in treat. of acute myelitis, 90 — — aphasia, 38 — — cerebral haemorrhage, 24 — — hyperaemia, 17 — paralysis, 57 concussion, cerebral, 51 facial paralysis, 184 myelitis, 90 spinal concussion, 114 — — hyperaemia, 78 sunstroke, 53 tetanus, 147 Arsemcum in treat. of angina pectoris, 203 - — acute myelitis, 89 — —— cerebral anaemia, 10 — -— -— softening, 37 -— — cerebro-spinal meningitis, 128 llllllllll — chronic hydrocephalus, 74 — delirium tremens, 252 — — encephalitis, 34 INDEX. 261 Arsenicum in treat. of enteralgia, 212 — —— astral ‘a, 206 -— — eadac e, 196, 217, 222 — -- hemicrania, 196 —- —- hysteralgia, 210 — — insomnia, 236 - -— mania 247 -— -— mastod nia, 175 -— — melanc olia, 238 — -- myehtis, 89 —— —- neuralgia, 168, 171 — -— neurasthenia, 119 -- -— puerperal convulsions, 136 — — sciatica 179 — -— spinal anaemia, 80 -- -— vertigo, 226 Asafoetida in treat. of headache, 219 Asclepias syr. in treat. of cerebral hyperzemia, 19 — — puerperal convulsions. 136 Asterias rub. in treat. of chorea, 155 Aurum in treat. of angina pectoris, 204 — —- cerebral hyperaemia, 18 — — — s hilis, 47 —- - locomotor ataxia, 108 — — mania, 246 — — melancholia, 238 Avena sat. in treat. of neurasthenia, 120 —- — -— cerebral anaemia, 11 Baptisia in treat. of cerebro-spinal meningitis, 125 Baryta carb. in treat. of aphasia, 38 — -— cerebral heemorrhage, 23 — — -— tumors, 49 — - locomotor ataxia, 110 -— -- multiple cerebral sclerosis, 43 Belladonna in treat. of acute myelitis, 89 — -— cerebral concussion, 51 - - — haemorrhage, 23 — hypersemia, 16 —— meningitis, 64 —— softening, 36 —- tumors, 49 cerebro-spinal meningitis, 127 coma, 231 delirium tremens, 250 epilepsy, 142 enteralgia, 213 facial paralysis, 184 astra ‘a, 207 eada e, 215 hemicrania, 196 hysteralgia, 210 infantile cerebral paralysis, 57 — convulsions, 130 insomnia, 233 locomotor ataxia, 109 mania, 245 melancholia, 138 myelitis, 89 neuralgia, 173 puerperal convulsions, 137 sciatica, 17 9 spasm of glottis, 190 spinal hyperaemia, 77 —- irritation, 83 —- meningitis, 86 sunstroke, 55 -— tetanus, 145 - — tubercular meningitis, 70 — -— vertigo, 226 Berberis in treat. of cerebral syphilis, 47 - -- headache, 215 — —- spinal hyperaemia, 77 Bismuthum in treat. of gastralgia, 208 — — headache, 219 -- —- neuralgia, 169 Bovista in treat. 1' headache, 217 lllllllllllllllllllllllllllll "llllllllllllllllllllllllllllll Bromides in treat. of cerebral hyperaemia, 21 Bromine in treat. of hemicrania, 197 exophthalmic goitre, 199 B1-yonia in treat. of cerebral hypereemia, 16 —— —- coma, 231 astral ia, 206 eadac e, 220 - — hemicrania, 197 — — mastodynia, 175 — — meningitis, cerebral, 65, 69 — — —— spinal, 86 — — — tubercular, 69 — - neuralgia, 169,172 — —- puerperal convulsions, 136 -- — sciatica, 178 —— — vertigo, 226 _— Cactus grand. in treat. of angina pectoris, 203 Calcarea carb. in cerebral tumors, 49 —- — chorea, 153 — -— hemicrania, 196 — -— hydrocephalus, 74 — —- hysteralgia, 210 —- — tubercular meningitis, 69 — -— vertigo, 229 Calcarea phos. in cerebral anaemia, 12 —— — chronic hydrocephalus, 75 - — headache, 222 ' — —- neurasthenia, 80, 119 — - spinal anaemia, 80 — —- tubercular meningitis, 69 Galois hypophos. in treat. of neurasthenia, 121 Camphor in treat. of cerebral anaemia, 11 — — coma, 231 -— — concussion, 51 — —- sunstroke, 53 Camphor brom. in treat. of infantile convul- sions, 130 Calendula in treat. of spinal concussion, 114 Cannabis ind. in treat. of cerebro-spinal men- in 'tis, 126 - — de irium tremens, 251 — - epilepsy, 141 Cantharis in treat. of cerebro-spinal menin- gitis, 128 Capparis cor. in treat. of epilepsy, 141 Capsicum in treat. of delirmm tremens, 251 Carbo veg. in treat. of gastralgia, 206 — - sunstroke, 53 Carbo an. in treat. of headache, 222 — — cocc godynia, 177 Caulophyl um in treat. of headache, 217 -- — hysteralgia, 210 Causticum in treat. of acute myelitis, 89 -— — aphasia, 38 — — chorea, 153 — — diphtheritic paralysis, 185 —— -— facial paralysis, 184 —- - headache, 216 — — myelitis, 90 — — ocular paralysis, 72 — -- vertigo, 228 Cedron in treat. of headache, 220 Chamomilla in treat. of aphasia, 40 — -— coma, 231 — —- enteralgia, 212 — - headache, 215 — — infantile convulsions, 132 — — mastodynia, 175 — — sciatica, 17 9 Chelidonium in treat. of headache, 219 China in treat. of cerebral anaemia, 10 -— - gastralgia, 207 — -— spinal anmmia, 80 - — verti o, 226 China ars. 1n treat. of e ilepsy, 143 China sulph. in treat. 0 neurasthenia, 119 -— - vertigo, 226 262 INDEX. Chlorine in treat. of spasm of glottis, 190 Cicuta in treat. of cerebral concussion, 51 — — cerebro-spinal meningitis, 125 —- -‘— coccygodynia, 176 ' —— — chorea, 154 — -- infantile convulsions, 132 —— — spinal concussion, 114 —- —- -— meningitis, 87 — — tetanus, 145 , -— — vertigo, 228 Cimicifuga in treat. of cerebral hyperaemia, 18 —- — -— meningitis, 66 —— — cerebro-spinal meningitis, 124 —- — chorea, 153 — — delirium tremens, 251 — -— hysteralgia, 210 —— — insomnia, 234 —— -— mastodynia, 175 —— — melancholia, 239 —— — ovaralgia, 209 —— — spinal irritation, 82 Gina in treat. of cerebral anaemia, 12 -— — chorea, 155 —- — infantile convulsions, 131 —— — tubercular meningitis, 70 Cinnabaris in treat of cerebral syphilis, 47 Coca in treat. of insomnia, 235 Cocculus in treat. of acute ascend. paralysis, 94 —- — cerebro-spinal meningitis, 127 —- — chorea, 154 —— —- epilepsy, 142 —- — gastralgia, 207 —- —- headache, 222 — —— insomnia, 235 —- -— spinal irritation, 82 — — vertigo, 227 Coffea in treat. of cerebral hyperaemia, 18 —- — insomnia, 235 Colchicum in treat. of aphasia, 38 -- —- neural ‘ , 170 —- — spinal yperaemia, 77 —- — vertigo, 228 Colocynthis in treat. of enteralgia, 212 —- -— gastralgia, 207- — -— headac e, 217 — — sciatica, 178 Conium in treat. of aphasia, 38 — -— cerebral concussion, 52 - — —- tumors, 50 —— -— coccyggodynia, 176 —- — neur gia, 170 —— -— ovaralgia, 209 —- — spinal concussion, 114 -- -— vertigo, 226 Corrallium rub. in treat. of spasm of glottis, 190 Crotalus in treat. of cerebro-spinal meningitis, 1 Crocus in treat. of headache, 222 —- —- mania, 247 Cuprum in treat. of angina pectoris, 203 -— — cerebral hyperaemia, 18 —- —- -- meningitis, 65 -— -— cerebro-spinal meningitis, 127 — —— chorea, 155 —- —- epilepsy, 142 -— -- enteralgia, 213 - - infantile convulsions, 131 - -- mania, 247 - — neuralgia, 172 — — puerperal convulsions, 135 — — spasm of glottis, 190 -— -- spinal meningitis, 87 — — vertigo, 225 Cyclamen in treat. of hemicrania, 197 Cypripglium in treat. of infantile convulsions, Digitalis in treat. of cerebral meningitis, 65 — —— chronic hydrocephalus, 74 — — cerebro-spinal meningitis, 125 — — puerperal convulsions, 136 — —- sunstroke, 54 Dioscorea in treat. of enteralgia, 212 Epiphegus in treat. of neurasthenia, 120 Ergot in treat. of cerebral hyperaemia, 21 Erythroxylon coca in treat. of neurasthenia, 80,119 — — spinal anaemia, 80, 119 Ether in treat. of sciatica, 180 Eupatonum perf. in treat. of headache, 219 Euphrasia in treat. of vertigo, 226 — —— headache, 217 Ferrum in treat. of cerebral anaemia, 11 — —- gastralgia, 208 Ferrum et strych. in treat. of ovaralgia, 109 Fluoric acid in coccygodynia, 176 Gamboge in treat. of headache, 221 Gelsemmm in treat. of acute ascending paral- ysis, 94 —- — myelitis, 89 —- cerebral concussion, 51 — — hyperaemia, 17 — — meningitis, 66 —- cerebro-spinal meningitis, 124 -—- delirium tremens, 252 —- diphtheritic paralysis, 186 — facial paralysis, 184 — headache, 218 — hemicrania, 196 — hysteralgia, 210 - infantile convulsions, 130 -— — cerebral paralysis, 57 —- insomnia, 233 -— locomotor ataxia, 109 —- mania, 247 — neuralgia, 169 — ocular paralysis, 73 —- ovaralgia, 209 -— puerperal convulsions, 137 —- spasm of glottis, 190 — spinal hyperaemia, 77 — -— -— irritation, 82 — — tetanus, 146 — -- vertigo, 228 Glonoin in treat. of angina pectoris, 203 —- — aphasia, 38 —- — cerebral concussion, 51 — -— -— hyperaemia, 15 —- -- —— meningitis, 65 — — epilepsy, 142 —- — infantile convulsions, 131 — — sunstroke, 53 Gossypium in treat. of headache, 220 Graphites in treat. of cerebral tumors, 49 Gymnocladus in treat. of headache, 219 llllllllllllllllllllll Hamamelis in treat. of neural ' , 168 Hepar sulpb, in treat. of spina concussion, 114 Helleborus in treat. of cerebral meningitis, 66 — — chronic hydrocephalus, 74 , -— — coma, 232 — —- infantile convulsions, 133 — — locomotor ataxia, 109 -— — tubercular meningitis, 69 Helonias in treat. of cerebral anaemia, 12 Hoang Nan in treat. of hydrophobia, 150 Hydrastis in treat. of headache, 220 Hydrocyanic ac. in treat. of cerebro-spinal men- ingitis, 126 INDEX. 263 Hydrocyanic ac. in treat. of epilepsy, 142 -— —- puerperal convulsions, 135 ~— — tetanus, 146 Hyoscyamus in treat. of cerebral concussion, 51 — — hyperaemia, 16 — — meningitis, 67 — — cerebro-spinal meningitis, 126 — — chorea, 154 — — delirium tremens, 251 —- — infantile convulsions, 132 — -- insomnia, 235 — — mania, 245 — —— puerperal convulsions, 136 — — vertigo, 227 Hypericum in treat. of cerebral concussion, 51 — — spinal concussion, 114 —- — — irritation, 83 —- —— —— meningitis, 86 — — tetanus, 147 Ignatia in treat. of cerebral anaemia, 11 —- — chorea, 154 — — gastral ia, 206 — — infanti e convulsions, 130 — — insomnia, 235 — —- locomotor ataxia, 110 — — melancholia, 238 — -— neuralgia, 172 — -— neurasthenia, 121 —— — ovaralgia 209 — — puerperal convulsions, 137 — —— sciatica, 179 -— — spinal irritation, 83 — — vertigo, 225 Indigo in treat. of epilepsy, 141 Inula helen. in treat. of hydrophobia, 150 Iodine in treat. of angina pectoris, 202 — — encephalitis, 34 — — melancholia, 239 — —- spasm of the glottis, 190 Ipecacuanha in treat. of cerebral anaemia, 12 -— — headache, 215 — — infantile convulsions, 133 — — spasm of glottis, 190 — -— vertigo, 228 Iris vers. in treat. of headache, 217 -— — hemicrania, 196 —— — neuralgia, 169 Kali bichr. in treat. of headache, 222 — — hemicrania, 197 — -— neuralgia, 170 Kali brom. in treat. of infantile convulsions, 130 — — melancholia, 239 — — spasm of glottis, 190 Kali carb. in treat. of cerebral tumors, 49 — — headache, 218 — —- neuralgia, 172 Kali chlor. in treat. of facial paralysis, 184 Kali cyan. in treat. of neuralgia, 170 Kali iod. in treat. of angina pectoris, 202 -— — aphasia, 38 — — cerebral syphilis, 47 -— —— chronic hydrocephalus, 75 — — facial paralysis, 184 -- — headache, 219 —- — ocular paralysis, 73 — — sciatica, 179 —- — spinal meningitis, 87 — — tubercular meningitis, 70 —- — vertigo, 227 Kali phos. 1n treat. oi melancholia, 238 —- — spinal anaemia, 80 Kalmia in treat. of neuralgia, 168 — — vertigo, 228 Lachesis in treat. of angina pectoris, 204 -— — aphasia 3 —— — cerebral concussion, 51 -— — — haemorrhage, 24 Lachesis in treat. of coma, 231 —- —- headache, 215 — — neuralgia, 169 -— — puerperal convulsions, 137 — — spinal hyperaemia, 77 — — tetanus, 146 —- - vertigo, 225 Lachnanthes 1n treat. of cerebral hyperaemia, 18 Lathyrus in treat. of locomotor ataxia, 109 -— — spinal hyperaemia, 78 Laurocerasus in treat. of angina pectoris, 203 — — cerebral haemorrhage, 25 —— —- -— concussion, 51 Ledum in treat. of paralysis, 94 Lilium tig. in treat. of headache, 221 -— -- ovaralgia, 209 Lycopodium in treatment of aphasia, 37 —— —- cerebro-spinal meningitis, 128 — — coma, 232 —- - headache, 217 — — melancholia, 238 — — spinal anaemia, 80 — — tubercular meningitis, 70 Magnesia phos. in treat. of neuralgia, 168 Mercurius in treat. of acute myelitis, 89 — — cerebral syphilis, 47 —- — facial paralysis, 184 — — headache, 220 -—— — mania, 246 — — myelitis, 89 —- —- ocular paralysis, 73 —- — sciatica, 180 —- —— spinal meningitis, 87 Mercurius iod. in treat. of encephalitis, 34 Mezereum in treat. of headache, 218 — - neuralgia, 168 172 Moschus in treat. of insomnia, 235 Mygale in treat. of chorea, 153 ~ .--~ Naja in treat. of ovaralgia, 209 Natrum carb. in treat. of vertigo, 225 Natrum iod. in treat. of angina pectoris, 202 Natrum mur. in treat. of cerebral anaemia, 13 — —- headache, 221 - — hemicrania, 198 — — melancholia, 239 — — neural ia, 169 — — spinal irritation, 83 — — vertigo, 228 Natrum nitrite in treat. of angina pectoris, 203 Natrum salicyl. in treat. of vertigo 225 Natrum sulph. in treat. of cerebra anaemia, 13 — - headache, 215 Niccolum sulph. in treat. of hemicrania, 198 Nicotinum in treat. of tetanus, 145 N ux mosch. in treat. of coma, 232 -— - headache, 216 Nux vom. in treat. of acute ascending paral- ysis, 95 — cerebral anaemia, 11 — —- haemorrhage, 24 -— —— hyperaemia, 17 — cerebro-spinal meningitis, 126 — chorea 154 — enteralgia, 212 — epilepsy, 140 — gastral ia, 205 - headac e, 218 -— infantile convulsions, 132 — insomnia, 234 - locomotor ataxia, 110 —- mania, 246 — melancholia, 238 — neuralgia, 170, 172 — neurasthenia, 120 - ocular paralysis, 73 264 INDEX. Nux vom. in treat. of sciatica, 178 — —— spinal anaemia, 79 — — — meningitis, 86 —- —- vertigo, 224 CEnanthe cr0. in treat. of epilepsy, 143 — —- puerperal convulsions, 137 Opium in treat. of cerebral haemorrhage, 23 -- -— — hyperaemia, 17 — — — meningitis, 66 -— — cerebro-spinal meningitis, 124 -— — coma, 231 —- — delirium tremens, 251 — — enteral ’ , 213 —- — infanti e convulsions, 231 — — insomnia, 234 —- — mania, 244 — — ocular paralysis, 73 -— — puerperal convulsions, 137 — — vertigo, 227 Oxalic acid in treat. of acute myelitis, 90 — —- gastralgia, 207 — — locomotor ataxia, 110 — — multiple cerebral sclerosis, 43 — — myelitis, 90 Passiflora in treat. of insomnia, 233 —— — tetanus, 146 Phosphorus in treat. of acute ascending paraly- sis, 95 — —- acute myelitis, 90 -— —— aphasia 38 —- — cerebral haemorrhage, 23 —— — — hyperaemia, 18 —— — cerebro-spmal meningitis, 126 -— — headache, 220 — — insomnia, 234 — — locomotor ataxia, 108 — — melancholia, 239 — —- multiple cerebral sclerosis, 43 — —— myelitis, 90 — —- neuralgia, 172 —— —- neurasthenia, 119 — — pseudo-hypertrophic paralysis, 100 — -— spinal anaemia, 79 — — vertigo, 224 Phosphoric ac. in treat. of coma, 232 — -— neurasthenia, 121 —— — vertigo, 228 Physosti a in treat. of locomotor ataxia, 109 — —— in antile convulsions, 133 — — spinal meningitis, 87 —- -- neurasthenia, 120 -— — tetanus, 146 — — vertigo, 228 Phytolacca in treat. of headache, 127 — —— mastodynia, 174 — -- spasm of glottis 190 Picric acidé treat. of acute ascending paraly- SIS, — — acute myelitis, 90 —- -— cerebral softening, 35 — — myelitis, 90 —- — neurasthenia, 120 Pilocarpus in treat. of pueliperal convulsions, 136 Platina in treat. of entera gia, 213 -— —- headache, 218 -— — melancholia, 239 Plumbum in treat. of acute myelitis, 89 — —— cerebro-spinal meningitis, 128 — —- chronic hydrocephalus, 75 — - encephalitis, 34 — —- enteralgia, 213 -— — epilepsy, 143 — — locomotor ataxia, 108 — — melancholia, 239 Plumbum in treat. of multiple cerebral sclero- SIS’ — — myelitis, 89 — — neuralgia, 170 —- -— sciatica, 179 —- — spasm of glottis, 190 —- — spinal meningitis, 87 Podophyllum in treat. of enteralgia, 212 — — headache, 218 Pulsatilla in treat. of cerebral anaemia, 12 —- — -- haemorrhage, 24 —- — —- hyperwmia, 19 —— — chorea, 154 —~ — coma, 231 -— — encephalitis, 34 —~ -— fiastralgia, 207 — — eadache, 221 — — hemicrania, 197 —- — insomnia, 235 — - mastodynia, 175 — -- melancholia, 238 — — neuralgia, 168 Rhododendron in treat. of neuralgia, 168 — — spinal hyperaemia, 77 Rhus rad. in treat. of hysteralgia, 210 —— — coccygodynia, 176 Rhus tox. in treat. of acute ascending paral- ysis 95 —- -— cerebral haemorrhage, 24 —- -— — hyperaemia, 18 —~ — cerebro-spinal meningitis, 127 —— -- coma, 231 —— — mastodynia, 175 —- — multiple cerebral sclerosis, 44 —— —— sciatica, 178 —~ -— spinal concussion, 114 —— — — hyperaemia, 77 —- — — irntation 83 —- — — meningitis 87 Rumex in treat. of headache, 221 Ruta in treat. of coccygodynia, 176 Sabina in treat. of neuralgia, 169 Sambucus in treat. of spasm of the glottis, 190 Sanguinariaintreat. of cerebral haemorrhage, 24 —- — headache, 222 — — hemicrania, 196 Scutellaria in treat. of headache, 221 -— — sunstroke, 53 Secale in treat. of acute ascending paralysis, 95 — — acute myelitis, 89 — — cerebral anmmia, 13 — —- hyperazmia, 21 — — coma, 232 — — myehtis, 89 —- —- spinal hyperaemia, 77 —- —— — irritation, 83 — — — meningitas, 87 Senegain treat. of vertigo 225 Sepia in treat. of cerebral haemorrhage, 25 — — — tumors, 49 —- — headache, 215 — — hemicrania, 195 —- —- hysteralgia, 210 — — mania, 247 — — neuralgia, 173 —- — vertigo, 227 . Silicea in treat. of cerebral syphilis, 47 — — epilepsy 143 -— — enceph 'tis, 34 — — headache, 216 -- — insomnia, 235 —- — locomotor ataxia, 110 -— — spinal h eraemia. 77 — — tubercu r meningitis, 71 — — vertigo, 225 INDEX. 265 Spigelia in treat. of angina pectoris, 203 Thuja in treat. of neuralgia, 172 — —- hemicrania, 197 —— —— coccygodynia, 176 - -- neuralgia, 167, 173 ‘ —- — ocular paralysis, 73 Spiraea ulm. 1n treat. of hydrophobia, 150 Spongia in treat. of angina pectoris, 202 — — tubercular menin itis, 70 Staphisagria in treat. 0 neurasthenia, 120 . . . . Stannum in -treat. of gastralgia, 208 _ — cerebr°'SP1na1menmg1t1s’ 126 -— — hemicrania, 196 '~_ _ coma’ 2.31 9 — — infantile cerebral paralysis, 57 _ _ asttalglaz "07 —- —— — convulsions, 132 _ _ . em1°¥ama: 197 _ Stillingia in treat. of headache, 221 — "' mfantlle c9nVu1s1°nSa 131 Stramonium in treat. of aphasia, 38 _ " melapqhoha’ 240 -— — cerebral hyperaemia, 16 _ _' myelmss 90 , — — —- meningitis, 65 "' _ neuralgla, 169 . . . _ _ chorea, 155 — — tubercular meningitis, 70 __ __ _ _" V6I't1g_0, . _ _ delirium tremens, 251 Veratrum V11‘. 1n tr_eat. of cerebral concussion , 55 - - headache, 218 — — —- hyperzemla. 11 _ , _ — - infantile convulsions, 131 — _ °e1'eb1'°'S_P_1na1men1ng1t1S, 124 — —- insomnia, 235 "' _ Phoreag 19° _ _ __ mania, 244 —— — lIIfH.DtII_B convulsions, 133 -— — ocular paralysis, 73 — _ msommai 234 . -- — puerperal convulsions, 136 — _ Puerperzfl convulslonsr 13 — — spinal meningitis, 87 " _ Sllnstroke, 53 ' - - tetanus, 146 - -, — t<?t=\11\1S,147 _ __ __ vertigo’ 227 V1pera 1n treat. of cerebral concussion, 53 Strychnia in treat. of cerebral softening, 36 Strycl1s%1§1£,hg3ée1§1itareg8- of neurasthemaa 80,119 Xanthium spin. in treat. of hydrophobia, 150 —— — — irritation, 82 Valerian in treatment of sciatica, 180 Veratrum alb. in treat. of acute myelitis, 89 — —— angina pectoris, 203 — -— cerebra anaemia, 12 Sulphur in treat. of cerebral anaemia, 13 Zinc brom. in treat. of cerebral anaemia, 12 —- — -- hyperaemia, 19 — — neurasthenia, 120 — — chorea, 155 Zinc oxyd. 1n treat. of multiple cerebral scle- — — chronic hydrocephalus, 74 rosis, 43 — — headache, 216 Zinc phos. in treat. of cerebral anaemia, 12 -— — insomnia, 236 — —— — softening, 36 -— —— multiple cerebral sclerosis, 44 -— — neuralgia, 170, —- —— vertigo, 228 — — neurasthenia, 121 Sulphuric ac. in treat. of spinal concussion, 114 Zinc picr. in treat. of cerebral anaemia, 12 —— — neurasthenia, 120 Zinc val. in treat. of insomnia, 235 Tanacetum in treat. of hydrophobia, 150 -— — ovaralgia, 209 Tartar emet. in treat. of coma, 231 Zincum in treat. of cerebral anaemia, 12 — -— neuralgia, 169 — — cerebro-spinal meningitis, 128 Tarantula in treat. of chorea, 154 —- — chronic hydrocephalus, 75 -— — coccygodynia, 176 — — chorea, 155 - -— mania, 248 — -— coccy odynia, 176 -- —- multi le cerebral sclerosis, 44 — — encep alitis, 34 -- -- spina irriration, 83 — — infantile convulsions, 132 —- — vertigo, 227 — — locomotor ataxia, 109 Tellurium in treat. of spinal irritation, 83 — — neuralgia, 173 Thaspium aur. in treat. of epilepsy, 143 — — neurasthenia, 120 SECTION III.—-FRENCH SYNONYMS. Abcw cérébrale, 32 Catale sie, 161 — du cerveau, 32 Cepha algie, 214 — dc l’encephale, 32 Commotion cérébrale, 50 Anemie cérebrale, 9 -— du cerveau, 50 —- cerebro-spinale, 117 -- de la moe'lle épiniere, 112 —- du cerveau, 9 —— spinale, 112 Anesthésie cutanée, 192 Congestion cérébrale, 14 Angine de poitrine, 200 -— cérébro-spinale, 116 Aphasie 37 —- du cerveau, 14 Aplasie iamineuse progressive, 191 Coup de soleil, 52 Apodplexie cérébrale, 21 Convulsions de 1’ enfance, 129 — e la moe'lle épiniere, 84 — des femmes encientes et en couche, 134 — méningée, 59 — toxémiques, 138 Arachnite spinale, 85 Crampe des écrivains, 188 Ataxie locomotrice, 107 Athetose, 44 Atrophie cérébrale, 40 Danse de St. Guy, 152 — du cerveau, 40 —- de St. Witt, 152 -— muscularie raisseuse progressive, 101 Degenerations secondaires de la moelle épi- —- partielle de a face, 191 niere, 162 266 INDEX. Délire crapuleuse, 250 — ebrieuse, 250 Démence 252 Diplegie faciale, 184 Douleur de téte, 214 -— de coccyx, 175 Embolie cérébrale, 30 Encephalite chronique, 32 Epilepsie, 139 Fievre cérébrale, 67 Folie musculaire, 152 —- raisonnante, 241 Fortraiture, 210 Fureur, 243 Gastralgie, 204 Goitre exophthalmique, 198 Haut mal, 139 Hématomyéle, 84 Hemorrhagie cérébrale interstitielle, 21 — des méninges, 59 — du cerveau, 21 — méningée cérébrale, 59 — intrarachienne, 84 Hydrocéphale, 73 Hydrophobie, 148 Hydropsie du cerveau, 73 Hyperémie cérébrale, 14 — cérébro-sginale, 116 — de la. moe le épiniere, 76 Hygértrophie cérébrale, 39 —- u cerveau, 39 Hypochondrie, 240 Hystérie, 156 — épileptiforme, 159 Hystér0~épi1epsie, 159 Inflammation de Parachnoide, 60 — de Pencephale, 32 — de la moelle épiniére, 88 Insomnie, 232 La chorée, 152 La rage, 148 Leptoméningite spinale, 85 Les dé enérations secondaires de la. moelle — épinlere, 106 Lypémanie, 237 Maladie de Graves, 198 — imaginaire, 156 Mal 5 téte, 214 — de mere, 156 — Divin, 139 Manie aigue, 243 —- era uleuse, 249 —— ebneuse, 249 -— sans déhre, 241 Mélancholie, 237 Ménin 'te oérébrale chronique, 71 — céré ro-rachidienne, 123 —; cérébr inale, épidémique 123 — consec-ut1fs 51a carie du roclmr, 61 — épidémique, 123 — granuleuse, 67 — simple, 62 — spinale, 85 Méningite tuberculeuse, 67 Mlgraine, 195 Monomanie affective, 241 Myélite 88 Myxédéme, 199 Névralgie, 167 — des mamelles, 174 — des ovaires, 208 — intestinale, 211 — sciatique, 177 Névrite, 166 Pachyméningite cérébrale, 58 — -— chronique, 71 — secondaire, 58 — spinale, 85 Paraplégie, 92 — functionelle, 78 — hypertrophique de Penfance, 98 — reflexe, 78, 93 Paralysie agitante, 164 — ascendante aigue, 94 — atrophique graisseuse de l’enfance, 97 — cérébrale, 56 — — de1’enfance, 56 —- de la lanque, 186 — diphthéritique, 185 — dn larynx, 99, 181 — du phartxinx, 99, 181 — essentie e de1’enfance, 97 —- faciale, 184 — générale incomplete, 163 - losso-labio-laryngée, 99 -— aryngée, 181 _ -— musculaire progressive atrophique, 101 — myosclérosique, 98 —- pharvn ée, 181 -— pseuElo- ypertrophique, 98 — spinale, 92 — — atrophi ue, 95 — — de Padu te, 95 — tremblante, 164 Perieneéphalite chronique diffuse, 163 Rachialgie, 81 Ramollissement cérébrale, 34 — de la moelle épiniiare, 88, 90 — spinale, 88, 90 Sclérose en plaques disséminées, 42, 103, 162 — latérale amyotrophique, 102 Spasme de la glotte, 189 - faciale, 187 Stupeur, 229 Syphilis du cerveau, 45 Tabes dorsal spasmodique, 105 Tétanos, 144 Thrombose cérébrale, 27 Tic-convulsif, 187 — douloureux, 171 Torticollis, 187 Trisme de Penfance, 134 ' Trophonévrose faciale, 191 ' Tumeurs de la moélle épiniére, 112 — du cerveau, 48 — rachidiennes, 112 Vertige, 223 INDEX. 267 SECTION IV.—-GERMAN SYNONYMS. Akute Convexitzits Meningitis, 61 — Spinallaihmung bei Erwachsenen, 95 —- und Chronische Enkephalitis, 32 All emeine Akute Hirnhautentzundung, 65 —- %’rogressive Gehirnlahmung, 163 Amyotrophique Lateral—sklerose des Riicken- mark Anaesthesia, 192 Anéimie des Gehirns, 9 Analsthesie, 192 Aphasie, 37 Apoplexie, 21 Athetose, 44, 56 Atrophie des Gehirns, 40 Basedow’scbe Krankheit, 198 Blcidsinn, 252 Brustbraune, 200 Cerebrale Abscess, 32 -— Eiterbeule, 32 — Geschwiir, 32 -— Kinderléihmung, 56 — Pachymeningitis, 58 — Typhus, 123 Cerebro-spinale Anéimie, 117 — — Hyperéimie, 116 Ghronische Convexitzits Meningitis, 71 — Hirnhautentziindun , 71 Convulsivische Starrsuc t, 161 Darmweh, 211 Der Wasserkopf, 73 . Diphtheritische Léihmung, 185 Diplegia Facialis, 184 Eiterbeule des Gehirns, 32 Eklampsieblutvergiftung, 138 — der Neugeborenen, 134 — in der Schwangerschaft und im Wochen- bette, 134 Embolie der Hirnarterien, 30 Enkephalentziindung, 32 Entziindung der Arachnoidea, 60 - der Nerven, 166 Epidemische Menin 'tis, 123 Erschiitterung des ehirns, 50 ~ des Riickenmarks, 113 Erweichung des Gehirns, 34 — des Riickenmarks, 85, 88, 90 Fallsucht, 139 Gehirnaniimie, 9 Gehirnatrophie, 40 Gehirnblutungen, 21 Gehirnerweichung, 34 Gehirnhypertroplne, 39 Gehirnléihmung, 54 Gehirnhyperalmie, 14 Gehirnapoplexie, 21 Geisteskrankheit, 243 Gemiithswahnsinn, 241 Genickkrampf, 123 Genickstarre, 123 Geschwiilste des Gehirns, 48 - des Rilckenmarks, 111 Gesichtkrampf, 187 Gesichtliihmung 184 Glotzaugenkrop , 198 Graue Degeneration der Hinterstriinge des Riickenmarks, 107 I-Ialsstarre, 187 Hiimatome der Dura Mater, 59 Hemicranie, 196 I-Iirnarterienversperrung, 27, 30 Hirnblutung, 21 Hirngeschwiir, 32‘ Hirn eschwiilste, 48 Hirn autentziindung, Akute, 65, 95 Chronische, 71 Hirnlabmun , 54 Hirnlustseuc 1e, 45 Hirnschlag, 21 Hirnwassersucht, 73 Hundswuth, 148 Hiiftweh, 177 Hyperamie des Gehirns, 14 Hypertrophie des Gehirns, 39 Hypochondrie, 240 Hysteric, 156 Hystero-Epilepsie, 159 Kehlkopfkrampf, 189 Kehlkopflithmung, 99, 181 Kinderzuckung, 129 Kinderkrampf, 129 Kinderstarrkram f, 134 Kinderlréihmung es,Gehirns, 56 'Kopfschmerz, 214 Krankhafte Geschwiilste des Gehirns, 84 — — des Riickenmarks, 112 Kreuzendschmerz, 175 Magenschmerz, 204 Melancholie, 237 Mi rane, 195 Mi zkrankheit, 240 Milzsucht 240 Multi le (lerebro-spingle Sklerose, 162 —- S erose des Gehirns, 42 — — des Riickenmarks, 103 Muskelatrophie, 98, 101 — mit Interstitieller Lipomatose, 98 Muskellahmung, 98, 101 Mutterbesohwerde, 156 Myxiideme, 199 Nerventziindung, 166 Neuralgie, 167 — der Brustdrtisen, 174 —- der Eierstocke, 208 — der Eingeweide, 211 — des Fiinftennerven, 171 — der Gebairmutter, 210 — der Ovarien, 208 — der Trigeminus, 171 Neuritis, 16:1 Paralytischer Blcidsinn, 163 I1:riIaI11a'.1'(_% I:3ateral€kler:)&se des 9Raiziickenmarks, 105 ar ysis seen ens cuta Poliomyelitis Anterior, 95 ’ Primalre Sfierogg der Seitenstriinge des Riicken- mar , 1 Progressive Bulbéirparalysie, 99 Prosopodysmorphia, 191 Reflex Paralysis Spinalis, 78 Riickenmarksapoplexie, 84 Riickenmarkshautentziindung, 85 Riickenmarksentziindung, 88 Ruckenmarkshyperamie, 76 Rimkgratschmerz, 81 268 INDEX. Schlaflosigkeit, 232 Schlagfluss, 21 Schlundkopfliihmung, 181 Schreibekrampf, 188 Schiittelkihmung, 164 Schwermuth, 237 Schwindel 223 Secundfiel3rkrankungEinze1ner Riickenmarks- strange, 106 — Cerebro-spinale Sklerose, 162 — Pachymeningite, 58 -— Leptomeningite, 61 Sonnenstich, 52 Spatische Spinalparalgsie, 105 Spinale H eréimie, -- Meningitis, Spinalmeningitis, 85 Spinalhihmung, 92 —- i Erwachsenen, 95 Spinalparalysie, 92 Sprachlahmung, 37 Starrkram f, 144 Steifer H s, 187 Stimmlosigkeit. 181 Stumpfsinn, 229 Syphflitische Gehirn Erkrankung, 45 pinalhyperalmie, 76 — Kinder 5 ung, Spinalkinderlahmung, 97 Thrombose der Hirnarterien, 27 - Cerebralis, 27 Tobsucht, 243 Tollheit 243 Tollwu , 148 Toxiimische Eklampsie, 138 Trunksucht, 249 Tuberculdse Hirnhautentziindung, 67 Unsinnigkeit, 243 Veitstanz, 152 Wasserko i, 73 Wassersc eu, 148 Wuth, 243 Zitterwahnsinn, 250 Zungenlaihmung, 186 ‘-——'_--E‘|889.__'-—=————~'~ , NEW CATALOGUE OF F. E. BOEBICKE’S STANDARD fiomceopatbic Publications. THE HAHNEMANN PUBLISHING HOUSE, 2921 Arch Street, Philadelphia. ALLEN, DR. TIMOTHY F. The Encyclopedia of Pure Ma- teria Medica; a. Record of the Positive Effects of Drugs upon the Healthy Human Organisln. With contributions from Dr. Richard Hughes, of England; Dr. C. Hering, of Philadelphia; Dr. Carroll Dunham, of New York; Dr. Adolph Lippe, of Philadelphia, and others. Ten volumes. Half morocco or sheep, $70.00. Cloth, . . $60.00 This Encyclopedia of Materia Medica, which is beyond question the most complete and extensive ever attempted in any country or languagefis truly worthy of its name; for it is a work to which the homoeopathic practitioner can turn with the certainty of finding the whole pathogenetic record of every remedy ever used in Homoeopathy. Pages could be filled with notices from the medical press in acknowledgment and appreciation of its great value. “ A glance at it is sufficient to show the student of materia medica the treasures it brings to hand. . . . There is abundance of fresh material for the physiological knowledge of Belladonna, Bismuth, Cannabis [etc.]. . . . Here is for°the first time a. full and in“ telligible pathogenesis of Bromine, of Cannabis Inclica, and of Carbolic Acid. . . . The ift is invaluable. \Ve can but again tender to Dr. Allen our grateful appreciation of his fabors.”-—Revz'ew of Vol. II in the British Journal of Ifomozopat/ty. “ With the Volumes IX and X now before us Ar.nr.x’s ENCYCLOPEDIA or PURE MATERIA MEDICA is completed. It comprises all remedies proved or applied by Homoeo- paths. With truly wonderful diligence everything has been carefully collated from the whole medical literature that could be put under contribution to Homoeopathy, thus enabling any one who wants to make a thorough study of Materia Medica, or who wants to read up a 2 STANDARD Hommorarnro PUBLICATIONS. *2 special remedy to find what he needs and where to look for it.” . . . —From the Allegemeine Homoeopathische Zeitmzg. ALLEN, DR. TIMOTHY F. A General Symptom Register of the Homoeopathic Materia Medica. Pp. 1,331. Large 8vo. Half morocco or sheep, $14.00; Cloth, . . . . . . . $12.09 This Index was urgently called for long before the Encyclopedia was com“ pleted, and no more convincing proof of its practical value could be adduced. It need only be added that the author’s promise to furnish the best arranged and most complete repertory ever attempted is more than fulfilled. The ingeni \-s selection and arrangement of type greatly facilitates its use. “The arrangement of this SYMPTOM REGISTER is simple enough to make the work readily available, and, judging from a few experimental trials, we are led to deem it an exhaustive Index of the majority of the symptoms of the Encyclopedia . . . Dr. Allen has fitly crowned his long and arduous labor, and placed us all under obligations that we can never repay.”——The American Observer. ‘\ “ Every scientific practitioner in the world will heartily thank the indefatigable author for crowning his pharmaco—encyclopedic edifice so promptly with a workable repertorial index. The thing we are most thankful for is that the arrangement is strictly alphabetical. FIRST, THE PART AFFECTED; SECOND, THE SENSATION, conditioned or modified. N o fads or fancies, theories or hypotheses. Of course, everybody has a copy of the Encyclopedia, and now everybody will get a copy of the Index. We cannot pretend to review such a work. It bears every mark of care, capability, and conscientiousness, and to hunt about for specks of dirt on such a grand picture is not the kind of work for us. The only piece of advice we offer to intending purchasers is that they ask for it bound in leather, for common cloth binding, no matter how nice to the eye, soon begins to tear at the back, and becomes the source of endless annoyance. This applies, of course, to a work for frequent reference, and Allen’s ‘Index’ is practically a dictionary to his Encyclopedia, and as such will be used many times a day.”—-From the Homoeopathic W/orld. ALLEN AND NORTON. Ophthalmic Therapeutics. See Nor- ton’s Ophthalmic Therapeutics. ALLEN, DR. WILLIAM A. Repertory of the Symptoms of Illtelunittellt Fever. Arranged by WILLIAM A. ALLEN. Pp. 107, 12mo. Cloth,.......... . ..........$1.00 We give a letter of Timothy F. Allen, M. D., recommending the publica- tion of this little work : “ I have carefully examined the repertory of Dr. \Vm. Allen, of Flushing, and assure you that it is exceedingly valuable. It should be printed in pocket form. I should use it constantly. Dr. Allen has a large experience in the treatment of intermittents, and his own observations are entitled to great respect.” . . . “Urged by other practitioners, he now offers to us [in the Repertory before us] the priceless fruits of his labors, and its daily use shall be our thank-offering. May it fulfill his and our own expectations.”-—North American Journal of Homoeopathy. STANDARD Homcnorarmo PUBLICATIONS. 3 ALLEN, DR. H. C. The Therapeutics of Intermittent Fever. By H. C. ALLEN, M. D., of the University of Michigan. Second edition, revised and enlarged. Pp. 342. 8vo. Cloth, . . . . . . . . . $2.75 This is the Second Edition of the author’s work, which originally appeared in 1879, found a rapid sale and met with a hearty reception from the pro- fession. It has been very carefully revised, and to meet an evident demand to the bracketed comparison of the former edition have been added some leading characteristics of each remedy, and a complete repertory. In advance of the malarial season, the homoeopathic practitioner can furnish himself with no bet- ter or more indispensable guide than this excellent monograph, as the following quotations will testify: “And now, is it too much to say that with its full Materia Medica, its comparisons, clinical illustrations, and repertory, all in good type, it is the best work on the subject that. has ever been issued ?"—A. F. Randall, M’. D., in lnvestigator. “ This work is a necessity where one has to cope with that often most discouraging of all diseases, and its careful study may insure success. You are not complete without it.”-—~ The Regular Physician. ARNDT, DR. H. R. A System of Medicine, based upon the Law Of Homoeopathy. In three volumes, royal octavo. Vol. I, 960 pages; vol. II, 900 pages; vol. III, 990 pages. Price per volume, bound in half morocco or sheep, 88.50; the complete work, $25.50. ‘ Price, per Volume, bound in cloth, $7.50; the complete work, . . . . . . . $22.50 This great work has been received with unqualified praise both in Europe and America, and has been unhesitatingly pronounced the most exhaustive work of its kind in homoeopathic literature. It is gratifying to see that the result of so much labor, the combined effort of so many of the best minds in our school has not been lost upon the profession: it is now clearly demonstrated that “A System of Medicine, Based upon the Law of Hbmaaopathy” will long remain a standard work in the homoeopathic school of medicine. The large demand for the work is especially encouraging, showing how many physicians realize that the books which are universally applauded are books to be bought and studied, or there will be no progress. The contents of the several volumes are as follows: VOL. I.—General Introduction-—Ohapter on Physical Diagnosis——Diseases of the Respiratory Organs-——Diseases of the Organs of Circulation—Diseases of the Organs of Digestion. VOL. II.-—Diseases of Blood-Glandular System—Diseases of Urinary Or- gans—--Diseases of the Genital and Reproductive Organs-—-Diseases of the Nervous System——Diseases of the Organs of Locomotion. VOL. III.—-Diseases of the Skin, of the Eye and Ear—Constitutional Diseases. 4 STANDARD Homcsomrnro PUBLICATIONS. -. _ “Arndt’s book is a great success. VVe shall advise it to our students in preference to any other system of practice.”—From a letter written by Dr. T. F. Allen. “ The work, if Vol. I is a sample, is creditable to the numerous contributors, to its editor, and to the publisher. The text is clearly rendered, is concise, and, so far as our reading shows, up to date in symptomatology, diagnosis, and pathology. “In regard to paper, printing, and binding, we desire to thank our industrious and pains-taking publisher for offering such a perfect book. Printed with virgin type, on ex- cellent paper, the book vies with, if it does not excel, any previous effort of any publishing house.”—.Hahnemanm'an Jllonthly. “ \Vhatever opinions one may have upon the contested points of homoeopathic practice, whether he be a loose prescriber or a strict Hahnemannian, he cannot fail to be proud of the handsome volume which Dr. Arndt here presents to his fellow practitioners. “It is a volume which, in extent and completeness, exceeds and excels anything of its kind yet published. . . . ‘ “The best portion of the volume, to our mind, is the chapter on diseases of the organs of digestion. This is worth the price of the volume.”-—-The Homoeopathic Physician. “This great work will be to the homoeopathic school what Reynold’s System of llfedicine and Ziemssen’s Encyclopedia of M'edicine is to the allopathic. The homoeopathic system of practice has never been represented, in this country at least, by a text-book on general practice which met the wants of that school. They have been deficient in the etiology, pathology, and diagnosis of disease. But this work is very complete in these respects, and is fully up to the requirements of the condition of medical science of to-day. Every disease treated of in this volume is written up in the most exhaustive manner. The therapeutics of each disease is concise, plain, and not incumbered with that amount of symptomatology which has been a great fault of homoeopathic works on practice. The characteristic or guiding symptoms are alone given, greatly increasing the value of the work. . . . —Chicag0 Inter- Ocean. BAEHR, DR. B. The Science of Therapeutics according to the Pr‘1nciples Of Hornoeopathy. Translated and enriched with numerous additions from Kafka and other sources. By C. J. HEMPEL, M. D. Two volumes. Pp. 1,387. Half morocco, . . . . . . . $9.00 “The descriptions of disease—no easy thing to write——are always clear and full, some times felicitous. The style is easy and readable, and not too prolix. Above all, the rela- tions of maladies to medicines are studied no less philosophically than experimentally, with an avoidance of abstract theorizing on one side, and of mere empiricism on the other, which is most satisfactory.”———From the British Journal of Homoeopathy. BELL, DR. JAMES B. The Homoeopathic Therapeutics Of Diarrhoea, Dysentery, Cholera, Cholera Morbus, Cholera Infantum, and all, other Loose Evacuations of the Bowels. By JAMES B. BELL, M. D. Third edition. Pp. 191. 8vo. Cloth, . . . . . . . . . 31.50 “‘Bell on Diarrhoea’ is a well-known classic that has for years been the daily com- panion of careful scientific prescribers. . . . Practitioners who have much to do with diarrhoea cannot afford to do without it. . . . The help afforded by this work has been the means of saving a great number of lives.” —The Homoeopathic World, London. STANDARD IIOMCEOPATHIO Punucnrrons. 5 “This little book, issued in 1809 by Dr. Bell, has long been a standard work in Homoe- opathic Therapeutics. \Ve feel quite within bounds in asserting that it has been the means under our law of saving thousands of lives. Than this no greater commendation could be penned. . . . . In this second edition, Dr. Bell has been assisted by Dr. Laird, of Maine; also by Drs. Lippe, William P. \Vesselhoeft, and E. A. F arrington. Thirty-eight new remedies are given; the old text largely rewritten ; many rubrics added to the reper- tory; anew feature, the‘ black type,’ for especially characteristic symptoms, introduced. “This is a typical homoeopathic work, which no homoeopathic physician can afford to be without. The typographical setting is worthy of the book.”—From the Ifomceopathic ystctan. BERJEAU, DR. J. PH. The Homoeopathic Treatment of Syphilis, Gonorrhoea, Spermatorrhoea, and Urinary Dis- eases. Revised, with numerous additions. By J. H. P. FROST, M. D. Pp.25G.12mo. Cloth, ..................$l.50 This valuable little book, compiled from the results of the experience of the best homoeopathic authorities, by Dr. Berjeau, of London, in 1856, has since been revised and enlarged by J. H. P. Frost, M. D., and is now perhaps the best and most concise presentation of the subject to be had. “ This work is unmistakably the production of a practical man. It is short, pithy, and contains a vast deal of sound practical instruction. The diseases are briefly described ; the directions for treatment are succinct and summary. It is a book which might with profit be consulted by all practitioners of homoeopathy.” -—-North American J ournul. BOERICKE and DEWEY, DRS. WIVI. A. and W. A. The Twelve Tissue Relnedies of Schiissler, comprising the Theory, Therapeutical Application, Materia Medica, and a Complete Repertory of these Retnedies. Arranged and compiled by WILLIAM BOERICKE, M. D., Professor of Materia Medica, and W. A. DEWEY, M. D., Professor of Anatomy, in the Hahnemann Medical College of San Francisco. Pp. 303. 8vo.Cloth,.........................$2.50 This is the most recent and most complete of all the works on the Schussler Remedies. Its superiority to previous books on the subject is attested by its rapid sale and the wide attention it has attracted. “This work is not a padded reprint of Schiissler’s Therapy, nor a mere compilation from the journals of additional cures by the Tissue Remedies; but is, in large part, original work, with the materials presented by Schiissler. The section on ‘The Relations of the Biochemic (Schiissler’s word) to the Homoeopathic Treatment,’ although short, is one of the most instructive we have read for a long time/’—DR. J. T. O’CONNOR in Htmoeopctthic Recorder. “The rapid strides which the use of the Tissue Remedies of Scluissler has made in the homoeopathic profession since their introduction, entitles this book to the closest attention. It is by far the most comprehensive and the fullest in every particular yet published on this subject.’ ’—The Homoeopathic News. 6 STANDARD HOMCEOPATHIC PUBLICATIONS. “The work is systematically arranged, the main point being devoted to the therapeu- tical application of the remedies, followed by a complete Materia Medica of the same, to which is added a carefully prepared repertory, which embraces every characteristic of the Twelve Remedies.’ ’--The Medical Visitor. BREYFOGLE, DR. W.‘L. Epitome of Homoeopathic Medi- cines. Pp. 383. 12mo. Cloth, . . . . . . . . . .s1.25 We quote from the author’s preface: “It has been my aim throughout to arrange in as concise form as possible, the leading symptoms of all well-established provings. To accomplish this, I have compared Lippe’s Materia Medica, the Symtomen-Codex, J ahr’s Epitome, Boenninghausen’s Therapeutic Pocket-Book, and Hale’s New Remedies.” BRIGHAM, DR. GERSHAM N. Phthisis Pulnionalis, or Tubercular Consumption. Pp. 224. 8vo. Cloth, . . $2.00 This interesting work on a subject which has been the “ Opprobium Med- icorum ” for generations past, has met with a favorable reception at the hands of the profession. It is a scholarly work and treats its subject from the stand- point of pure Homoeopathy. . “Our author’s work must be pronounced as decidedly able, and its principal defects are those of the subject itself in its present state of development. In our opinion the whole question is still involved in too much doubt and difiiculty to admit of its being handled very lucidly at present. Dr. Brigham tries very hard to clear the deck of all no- tions that might be in the way of handling the subject scientifically, but he does not quite succeed even in defining clearly one single form of phthisis. Why? Because in the present state of the subject it is impossible for any man to do so, and we question whether a much better book on phthisis is possible at present.”—From the Homoeopathic IVorlcl. BRYAN T, DR. J. A Pocket Manual, or Repertory of Ho- II1(B01)€tl3l1i(3 Medicine, Alphabetically and N osologically arranged, which may be used as the Physicians’ Vade-mecum, The Traveler’s Med- ical Companion, or the Family Physician. Containing the Principal Remedies for the most important Diseases; Symptoms, Sensations, Charac- teristics of Diseases, etc.; with the Principal Pathogenetic Effects of the Medicines on the most important Organs and Functions of the Body, to- gether with Diagnosis, Explanation of Technical Terms, Directions for the Selection and Exhibition of Remedies, Rules of Diet, etc. Compiled from the best Homoeopathic authorities. Third edition. Pp. 352. 18mo. Cloth, BURNETT, DR. J. COMPTON. Essays: Ecce Medicus; Natrum Muriaticum; Gold; The Causes of Cataract; Curability of Cataract; Diseases of the Veins; Supersalinity of the Blood. Pp. 296. 8vo. Cloth, STANDARD HOM(EOPATHIC PUBLICATIONS. 7 Dr. Burnett’s essays were so favorably received in this country that they would undoubtedly have commanded a very large sale, had they not been so high in price. As it was, the six essays would have cost over five dollars, and in order to bring them within reach of the many we reprinted them, by special arrangement with the author, who contributed a new essay, “The Causes of Cataract,” not hitherto published, and a general introduction to the volume. The book is printed in good style, on heavy toned paper and well bound, and we are able to furnish it at less than half the price of the imported volumes. “This brilliant little book . . . forms by far the fullest record of the life of Hahne~ mann, as it gives also the best estimate of his character and of his work, with which we are acquainted. Rarely, if ever, have we met with a more sparkling, more attractive piece of reading. . . . It is the work of a master in literature.”——From a notice of Ecce Medicus in Jllonthly Homceopathic Review. BUTLER, DR. JOHN. Electricity in Surgery. Pp. 111. 12mo. Cloth, This interesting little volume treats of the application of Electricity in Surgery. The following are some of the subjects treated of: ENLARGEMENT or THE PROSTATE; STRICTURE; OVARIAN CYsTs; ANEURISM; NAEVUS; TUMORS; ULCERS; HIP DISEASE; Sranms; Bnmrs; GALVANO-OAUTERY; HEMORRHOIDS; FISTULZE; PROLAPSUS or RECTUM; HERNIA, ETC., ETC. The directions given under each operation are most explicit and will be heartily welcomed by the practitioner. BUTLER, DR. J OHN . A Text-Book of Electro-Therapew tics and Electro-Surgery. FOR THE USE or STUDENTS AND GENERAL PRACTITIONERS. By J OHN BUTLER, M. D., L.R.C.P.E., LR. C.S.I., etc., etc. Second edition, revised and enlarged. Pp. 350. 8vo. Cloth,..........................$8.00 “ WVe have nothing to add in hearty commendation of this work to our notice of the first edition. . . . It is undoubtedly the best book on uterine surgery, and the only scientific one on elcctro-therapeutics now before the public.”——The Homceopathic Times. “Among the many works extant on Medical Electricity, we have seen nothing that comes so near ‘filling the bill’ as this. The book is sufficiently comprehensive for the student or the practitioner. The fact that it is written by an enthusiastic and very intelligent homoe- opathist, gives to it additional value. It places electricity on the same basis as other drugs, and points out by specific symptoms when the agent is indicated. The use of electricity is, therefore, clearly no longer an exception to the law of similia, but acts curatively only when used in accordance with that law. We are not left to conjecture and doubt, but can clearly see the specific indications of the agent in the disease we have under observation. The author has done the profession an invaluable service in thus making plain the pathogenesis of this wonderful agent. The reader will find no difiiculty in following both the pathology 8 STANDARD HoMcEoPATnIo PUBLICATIONS. and treatment of the cases described. Electricity is not held up as the cure-all of disease, but is shown to be one of the most important and valuable of remedial agents when used in an intelligent manner. We have seen no work which we can so heartily recommend as this.’ ’ — Cincinnati Jlfedical Advance. CLEVELAND, DR. 0. L. Salient Materia Medica and Therapeutics. By C. L. CLEVELAND, M. D.,Lecturer on Materia Medica in the Homoeopathic Medical College, Cleveland, Ohio. Pp. 160. Small8vo.Cloth,................ .3125 The object of this book is to furnish the homoeopathic physician and student with a simple, salient, practical, and thoroughly reliable work on Materia Medica and Therapeutics. The one hundred and ninety-seven drugs presented are those most commonly used. “The monograph is very suggestive, and will be found a useful aid in the selection of remedies.”—New York llledical Times. “It would be difiicult to choose between Guernsey’s ‘Keynotes’ and Cleveland’s ‘Salient Materia Medica.’ Both are of pocket size; both are quite reliable. They will scarcely take the place of Johnson’s ‘ Key ’ in the pockets of the students. They ought not to replace a full symptomatology on the table of a physician, and still they refresh our minds, and will serve as companions in studying larger works. The truth is that Cleveland contains much that Guernsey lacks and vice versa; one needs them both.”—— * * * in North American Journal of Homoeopathy. DUNHAM, CARROLL, A. M., M. D. Homoeopathy the Science Of Therapeutics. A collection of papers elucidating and illustrating the principles of Homoeopathy. Pp. 529. 8vo. Half morocco, $4.00;Cloth,.............. .......$3.00 “More than one-half of this volume is devoted to a careful analysis of various drug- provings. It teaches us Materia Medica after a new fashion, so that a fool can understand, not only the full measure of usefulness, but also the limitations which surround the drug. . . We ought to give an illustration of his method of analysis, but space forbids. VVe not only urge the thoughtful and studious to obtain the book, which they will esteem as second only to the Organon in its philosophy and learning.”—-The American Homaeopathist. DUNHAM, CARROLL, A. M., M.D. Lectures on Materia Medica. Pp. 858. 8vo. Half morocco, $6.00; Cloth, . . . l$5.()O “Vol. I is adorned with a most perfect likeness of Dr. Dunham, upon which stranger and friend will gaze with pleasure. To one skilled in the science of physiognomy there will be seen the unmistakable impress of the great soul that looked so long and steadfastly out of its fair windows. But our readers will be chiefly concerned with the contents of these two books. They are even better than their embellishments. They are chiefly such lectures on Materia Medica as Dr. Dunham alone knew how to write. They are preceded quite naturally by introductory lectures, which he was accustomed to deliver to his classes on general therapeutics, on rules which should guide us in studying drugs, and on the therapeutic law. At the close of Vol. II we have several pages of great interest, but the most important fact of all is that we have over fifty of our leading remedies pre~ STANDARD HOMCEOPATHIC PUBLICATIONS. 9 sented in a method which belonged peculiarly to the author, as one of the most successful teachers our school has yet produced. . . . Blessed will be the library they adorn, and the wise man or woman into whose mind their light shall shine.”—Oinc'imzat'i llledical Advance. EDMONDS, DR. W.‘ A. A Treatise on Diseases Peculiar to Infants and Children. By ‘V. A. EDMONDS, M. D., Professor of Paedology in the St. Louis Homoeopathic College of Physicians and Sur- geons, etc., etc., etc. Pp. 300. 8vo. Cloth, . . . . . . . . . . $2.50 “The most concise and practical treatise on this very important subject yet given to the profession. It is not an exhaustive work, but a most plain and readily useful one. It contains in brief what Duncan and others have elaborated without necessity or advantage. . . We heartily commend the book as the cheapest and best extant.”-—T/ze llledical Gall. EGGERT, DR. W. The Homoeopathic Therapeutics of Uterine and Vaginal Discharges. Pp. 543. 8vo. Half mo- rocco,..................... .$3.50 The author has here brought together in an admirable and comprehensive arrangement everything published to date on the subject in the whole homoe- opathic literature, besides embodying his own abundant personal experience. The contents, divided into eight parts, are arranged as follows :——PART I. lllenstmtation and Dysvnenorrhcea. PART II. Zllenorrhagia. PART III. Amen- orrhwa. PART IV. Abortion and Miscarriage. PART V. illetrorrhagia. PART VI. Fluor albus. PART VII. Lochia, and PART VIII. General Conoomitants. FARRINGTON, DR. E. A. A Clinical Materia Medica. By E. A. FARRINGTON, M.D., Late Professor of Materia Medica in the Hahne- mann Medical College of Philadelphia. Edited by CLARENCE BARTLETT, M.D. Pp.752. Cloth,. . . . . . . . . . . . . . . . . . .$6.0() Halfmorocco, The great book for the student. “There is scarcely a practitioner in our school but will find a hint in every lecture worth the cost of the book . . . . We think it the best book published in our school in 1887 .”-—The Medzcat Advance. “The volume thus presented to the profession is a worthy monument to the originality, the enthusiasm and the indefatigable energy of the author. As a work on Materia Medica it is of such unique arrangement, that it can hardly enter into competition with, while it may invaluably supplement the present occupants of that important field. . The work, as a whole, is a possession on which homoeopathy may congratulate itself.”-— The New England Medical Gazette. GUERNSEY, DR. H. N. The Application of the Principles and Practice of Homoeopathy to Obstetrics and the Dis- orders Peculiar to Women and Young Children. By HENRY N. GUERNSEY, M.D.,Professor of Obstetrics and Diseases of Women 10 STANDARD HOMCEOPATHIC PUBLICATIONS. and Children in the Homoeopathic Medical College of Pennsylvania, etc., etc. With numerous Illustrations. Third edition, revised, enlarged, and greatly improved. Pp. 1004. 8vo. Half morocco, . . . . . . $8.00 In 1869 this sterling work was first published, and was at once adopted as a text-book at all homoeopathic colleges. In 1873 a second edition, considerably enlarged, was issued; in 1878 a third edition was rendered necessary. The Wealth of indications for the remedies used in the treatment, tersely and suc- cinctly expressed, giving the gist of the author’s immense experience at the bedside, forms a prominent and well-appreciated feature of the volume. GUERNSEY, DR. H. N. Key-Notes to the Materia Medica. As taught by HENRY N. GUERNSEY, M. D. Edited by J os. C. Guernsey, A. M., M. D. Pp. 267. Small 8vo. Cloth, . . . . . . . . . . $2.25 “If we are not mistaken, this will prove one of our best and most convenient books for 0ffice reference. The most serious defect is its brevity. We could wish there was more of it.”—Medical Advance. “ This work will no doubt receive a hearty welcome at the hands of the many admirers -of the late and lamented author. Of his conscientious labors in homoeopathic therapeutics ‘we need not speak, for his name stands as almost synonymous with pains-taking study of symptomatology. In the character of ‘ Key-Notes.’ . . . [it] . . . will prove service- able to the student and busy practitioner.”—The Hahnemannian Monthly. “ N 0 man ever was more fitted to compile awork of this sort than the late Dr. Guernsey ; keen and critical in observing symptoms, enthusiastic in reporting the successful use of the remedy, he was ever on the alert to catch the genius of the drug and to find its similitude in the patient.”—North American Journal of Homoeopathy, March, 1887. GUERNSEY, DR. E. Homoeopathic Domestic Practice. With full Descriptions of the Dose to each single Case. Containing also Chapters on Anatomy, Physiology, Hygiene, and abridged Materia Medica. Tenth enlarged, revised, and improved edition. Pp. 653. Half leather, Price,..........................$2.5O HAGEN, DR. R. A Guide to the Clinical Examination of Patients and the Diagnosis of Disease. By Rrcrman HAGEN, M.D., Privat docent to the University of Leipzig. Translated from the second revised and enlarged edition, by G. E. GRAMM, M.D. Pp. 223. 12mo.Cloth,............. .. ..$1.25 “ This is the most perfect guide in the examination of patients that we have ever seen. The author designs it only for the use of students of medicine before attending clinics, but we have looked it carefully through, and do not know of 223 pages of printed matter any- where of more importance to a physician in his daily bedside examinations. It is simply invaluable.”—From the St. Louis Clinical Review. HAHNEMANN, DR. S. Organon of the Art of Healing. By SAMUEL HAHNEMANN, M.D. Aude Sapere. Fifth American edition. STANDARD HOMGIOPATHIC PUBLICATIONS. 11 Translated from the fifth German edition, by C. WESSELHOEFT, M.D. Pp.244. 8vo. Cloth,...................$1.75 " “ Every homoeopathic physician and undergraduate should be owner of a copy of this wonderful work, should read it very carefully and often, and ponder over its contents. Our . word for it, gentlemen, you will be the better for it as physicians and homoeopathists, and . you will be often surprised to find that on subjects which to your minds were obscure Hahnemann sheds a perfect flood of light which renders them so bright and well defined, - that even he who runs may read. “ To insure a correct rendition of the text of the author, they (the publishers) selected as his translator Dr. Conrad Wesselhoeft, of Boston, an educated physician in every respect, and from his youth up perfectly familiar with the English and German languages, than whom no better selection could have been made. That he has made, as he himself de- clares, ‘an entirely new and independent translation of the whole work,’ a careful compar- ison of the various paragraphs, notes, etc., with those contained in previous editions gives abundant evidence; and while he has, so far as possible, adhered strictly to the letter of Hahnemann’s text, he has at the same time given a pleasantly flowing rendition that avoids the harshness of a strictly literal translation.”—Hahneanannian lllonthly. HALE, DR. E. M. Lectures on Diseases of the Heart. In three parts. Part I. Functional Disorders of the Heart. Part II. In- flammatory Afl'ections of the Heart. Part III. Organic Diseases of the Heart. Second, enlarged edition. Pp. 248. 8vo. Cloth, . . . . $1.75 “After giving a thorough overhauling to the lectures of Dr. Hale, with the full inten- tion of a close criticism, I acknowledge myself conquered. True, there are text-books on the same subject of thrice the number of pages—-more voluminous, but not so concise; and in this very conciseness lies the merit of the work. Students will find there everything they need at the bedside of their patients. It fills just a want long felt by the profession.”—- North American Journal of .Homoeopathg/. HALE, DR. E. M. Materia Medica and Special Thera- peutics of the New Rernedies. By EDWIN M. HALE, M. D., Professor of Materia Medica and Therapeutics of the New Remedies in Hahnemann Medical College, Chicago, etc., etc. Fifth edition, revised and enlarged. In two volumes—Vol. I. Special Symptomatology. With new Botanical and Pharmacological Notes. Pp. 7 70. 8vo. Half morocco, $6.00;Cloth,.......................$5.00 5‘ Dr. Hale’s work on New Remedies is one both well known and much appreciated on’ this side of the Atlantic. For many medicines of considerable value we are indebted to his researches. In the present edition the symptoms produced by the drug investigated, and those which they have been observed to cure, are separated from the clinical observa- tions, by which the former have been confirmed. That this volume contains a very large amount of invaluable information is incontestable, and that every effort has been made to secure both fullness of detail and accuracy of statement is apparent throughout. For these reasons we can confidently commend Dr. Hale’s fourth edition of his well-known work on the New Remedies to our homoeopathic colleagues.”—From the London Homoeopathir: Review. 12 STANDARD HOMCEOPATHIC PUBLICATIONS. HALE, DR. E. M. Materia Medica and Special Thera- peutics of the New Remedies. By Enwm M. HALE, M. D. Vol. II. Special Therapeutics. With illustrative cases. Pp. 901. 8vo. Half morocco, $6.00; Cloth, . . . . . . . . . . . . . . . . .$5.00 “Hale’s New Remedies is one of the few works which every physician, no matter how poor he may be, ought to own. Many other books are very nice to have and very desir- able, but this is indispensable. This volume before us is an elegant specimen of the printer’s and binder’s art, and equally enjoyable when we consider its contents, which are not only thoroughly scientific, but also as interesting as a novel. Thirty-seven new drugs are added in this edition, besides numerous additions to the effects of drugs, previously discussed. . . . We must say and reiterate, if necessary, that Dr. Hale has hit the nail on the head in his plan for presenting the new remedies. It does well enough to tabulate and catalogue, for reference in looking up cases, barren lists of symptoms, but for real enjoyable study, for the means of clinching our information and making it stand by us, give us vol- umes planned and executed like that now under consideration.”-—Fr0m the New England Medical Gazette. HALE, DR. E. M. Medical and Surgical Treatment of the Diseases of Women, especially those causing Sterility. Second edi- tion. Pp. 378. 8vo. Cloth, . . . . . . . . . . . . . . . . $2.50 “This work is the outcome of a quarter of a century of practical gynaecological experi- ence, and on every page we are struck with its realness. It is one of those books that will be kept on a low shelf in the libraries of its possessors, so that it may be found readily at hand in case of need. . . . “In many obstinate uterine cases we shall reach this book down to read again and again what this clinical genius has to say on the subject. We have never seen Professor Hale in the flesh, but we have had scores of consultations with him in the pages of his New Remedies, and he has thus fearlessly helped us cure many an obstinate case of disease.” --From the Howzceopathie World, London. HART, DR. C. P. Diseases of the Nervous System. Being a Treatise on Spasmodic, Paralytic, Neuralgie, and Mental Affections. For the use of Students and Practitioners of Medicine. By CHAS. PORTER HART, M.D. Pp. 409. 8vo. Cloth, . . . . . . . . . . . . . $3.00 “This work supplies a need keenly felt in our school——a work which will be useful alike to the general practitioner and specialist; containing, as it does, not only a condensed compilation of the views of the best authorities on the subject treated, but also the author’s own clinical experience; to which is appended the appropriate homoeopathic treatment of ' each disease. lt is written in an easy, flowing style, at the same time there is no waste of words. . . . We consider the work a highly valuable one, bearing the evidence of hard work, considerable research and experience.”—Medico-Chirurgieal Quarterly. HART, DR. 0. P. A Treatise on Intracranial Diseases. By CHAs. PORTER HART, M.D., Honorary Member of the College of Physi- cians and Surgeons of Michigan, etc. Pp. 312. 8vo. Cloth, . . . $2.00 The Author’s Nervous System, with above as Supplement, bound in one. Price, SPANDARD HOMCEOPATHIG PUBLICATIONS. 13 “Well bound, beautifully printed, up to the times in pathology, replete with homoeo- pathic therapeutics, supplemental and completory of the author’s work on Nervous Diseases -—these are its qualifications.”——H'ahnemannian Monthly, April, 1884. “ It is written in Dr. Hart’s elaborate manner, clear and unambiguous, and will prove a valuable guide to the proper understanding and treatment of imflammatory, organic, and symptomatic affections of the brain and its membranes.”-—American Observer. “ We are glad to observe how closely our author adheres to the rigid (and hence suc- cessful) homoeopathic method of prescribing. Even in insomnia, where the temptation to use chloral, etc., is so pressing we have given us the truth—to the exclusion of empirical nonsense.”-—Homa;opathic Physician, April, 1884. HELMUTH, DR. W. T. A System of Surgery. By WM. Ton HELMUTH, M.D. Fifth edition. Enlarged, re-arranged, revised; many parts re-written, and much new matter added. Illustrated with 718 wood- cuts. Bound in full leather. Ppfllll. Royal octavo, . . . . . $9.00 Whether he like it or not, every doctor will at some time be called upon to do a little surgery, in view of which no homoeopathiaphysician can afford to be without Dr. Helmuth’s great work, which is admirably adapted to the needs of the general practitioner. It is the work also for the special student, and him we would remind that surgery of to-day is not what it was ten years ago, and the difference between the preceding and our author’s present edition is one of great importance. The work has for many years been used as a standard text-book in all homoeopathic colleges, and will long maintain its rank as the best work on the subject ever brought out by our school. Ever since it was issued the necessity for student or practitioner to invest in allopathic works on the subject ceased to exist, and now that this new fifth edition, which is up to date, abounding in valuable hints, and giving the results of the author’s ripe and extensive ex- perience in homoeopathic medication in connection with surgery-now that all this, in our author’s forceful, elegant diction is placed before the profession, it is certainly to be doubted if a work better adapted to the needs of the practi- tioner can be found anywhere. “ We gladly welcome the fifth edition of this standard work, without which no homoeo- pathic physician can consider his library complete. The author has succeeded in his endeavor to make it ‘an exponent of the surgery of the present,’ and a volume suited alike to the requirements of student and surgeon; moreover, it is written in so interesting a manner that its perusal is a matter of pleasure as well as profit.’ ’——B. W. J'., in the Hahnemannian Monthly. “ This is THE homoeopathic work on surgery. The author stands in the front rank as a skilled operator. He has few equals and no superiors. The book is a marvel.”—St. Louis Periscope. “For years Dr. Helmuth’s Surgery has been the pride of every Homoeopath; both practitioner and student have looked to it for guidance and direction as authority in all surgical matters. We had thought it almost impossible to improve the work, bu‘ we 14 STANDARD HOMGSOPATHIC PoBLrcAT1oNs. really think this edition now before us is the best that has appeared. There has been so much new matter added that any one who now possesses a. former edition will . . . re- quire this issue in order to be up with the times.”—-The Medical Advance, January, 1887. HELMU TH, DR. W. T. Supra-Pubic Lithotomy. The High Operation for Stone—-Epicystotomy-—Hypogastric Lithotomy ——“ The High Apparatus.” By WM. TOD HELMUTH, M. D., Professor of Surgery in the N. Y. Horn. Med. College; Surgeon to the Hahnemann Hospital and to Ward’s Island Homoeopathic Hospital, N. Y. 98 quarto pp.-—-8 lithographic plates. Cloth, . . . . . . . . . . . . . . . . . $4.00- A superb quarto edition, with lithographic plates, printed in five colors, and illustrated by charts and numerous wood-cuts. “ Here is a handsome folio volume, beautifully bound in gray muslin, with red edges, fine paper, handsome type, illustrated by artistic lithographic plates and numerous wood- cuts, that at once attracts the eye of the lover of books. The name of the author is a cer- tain guarantee of its literary and scientific value. . . . The book commends itself, not so much on account of the thoroughness with which it has been prepared, as from the fact that it is a masterly plea for a form of operation that it would seem has long been unjustly under the ban of surgical censure. . . . In this bold and original work Helmuth has opened up a new field for study, ably and abundantly fortified his positions, and given en- couragement for the hope that even the low ratio of mortality from lithotomy operations that modern methods have secured, will in the future be still further reduced.”—ll[edical Counselor. “One can see on every page that Professor Helmuth worked here can amore, that his whole soul was in it. . . . The work is so practical that any one can understand its mean- ing.”—-North American Journal of Homoeopathy. “Dr. Helmuth is well known as a skillful, bold, and successful operator. . . . The work redounds greatly to his honor on account of its highly scientific character. . . . We are proud to find that our homoeopathic school has contributed such a valuable treatise to surgery, and trust it will receive the attention it merits.”——British Journal of Homoeopathy. HEINIGKE, DR. CARL. Pathogenetic Outlines of Homoeo- pathic Drugs. By Dr. CARL HEINIGKE, of Leipzig. Translated from the German, by EMIL TIETZE, M. D., of Philadelphia. Pp. 576. Svo. Cloth,..........................$3.50 “The reader of this work will gain more practical knowledge of a given drug from its pages in the same space of time than from any other book on the same subject. “ To the English-reading portion of our colleagues this book will be a boon to be appreciated in proportion that it is consulted, and will save them many weary researches when in doubt of the true homoeopathic remedy.”-—American Homoeopath. I-IERING, DR. CONSTANTINE. Condensed Materia Med- ica. Third edition, more Condensed, Revised, Enlarged, and Improved. Edited by Dr. E. A. FARRINGTON, Professor of Materia Medica. Pp. 960. Large8vo. Halfmorocco, . . . . . . . . . . . . . . . . . $7.00 STANDARD HoMcEoPATH1c PUBLICATIONS. 15 Having stood the test of time, this well-known and standard work on Con- densed Materia Medica needs no flattering array of press notices to recommend it anew to the rising homoeopathic profession. We need only call attention to the work done by the able editor in his revision of the text for this, the third edition, and to this end we quote from his preface: _ “In the preparation of this . . . edition . . . additions have been made, and a few typographical errors corrected, but, in justice to the lamented author, no alterations have been made in the substance of the text as he left it. “ More than twenty new remedies, arranged after the plan of the book, are given in full, and over forty partially proved drugs, with brief but distinctive indications, are added to the sections on ‘Relationship.’ Besides all this, about six hundred choice and well- attested symptoms have been incorporated in their proper place in the text. All the late works have been drawn upon for the new material, and even private sources have been unsparingly taxed; but still, great caution has been used in making selections. The plans and purposes of the work demand clinical as well as pathogenetic symptoms. But of the former sort only those have been employed which agree with the provings, and which show every evidence of Igenuineness. Such discrimination demands the exercise of one’s best judgment and the expenditure of much time. But it is believed the benefits to be derived far outweigh the trouble. The book is now offered to the profession and to students, not as a rival of other works, but as a rich treasury full of information common to homoeopathic literature, and also of gleanings from the vast collection which Dr. Hering made during a busy half century of medical study and labor.” HERING, DR. CONSTANTINE. Domestic Physician. By ‘CoNsTANTINE HERING, M.D. Seventh American Edition. Pp. 464. Price,..... ...s2I50 The present editor, Claude R. Norton, M.D., a former assistant of Dr. Hering, undertook, at his desire, the task of superintending the publication of the work. Some additions to the text have been made, a few remedies intro- duced, and, at times, slight alterations in the arrangement effected, but the well- known views of the author have been respected in whatever has been done. “ Hering’s Domestic Physician was loaned to me some thirty years ago to investigate homoeopathy, and throughout these long years it has remained my valued companion.”—- Dr S’. Lilienthal in the North American Journal of Homwopathy. “In the country or in a locality where no good homoeopathist lives, this book is in- valuable. As a case in point, we remember hearing of a lady who prescribed for her mother in Paris in a case so serious that two allopathists gave a gloomy prognosis. The lady care- fully studied the case, gave the remedy and in the morning the two regulars were very much surprised to see the improvement.”——T he Hornoeopathic Physician. HOLGOMBE, DR. W. H. ,HoW I became a Homoeopath. An interesting pamphlet of 28 pages. 8vo. Paper cover. Price, $0.15 Perdoz.,......................... 1.25 ]:IOM(EOPATHIC POULTRY PHYSICIAN (Poultry Veteri- narian); or Plain Directions for the Homoeopathic Treatment of the most Common Ailments of Fowls, Ducks, Geese, Turkeys, and Pigeons, l8 STANDARD HoMo.=:o1>ATRIo PUBLICATIONS. based on the author’s large experience, and compiled from the IIIOSL reli- able sources, by DR. FR. SCHR6TER. Translated from the German. Pp. 86.l2mo.Cloth,.....................$0.50 H()M(EOPATH1C COOKERY. Second edition. With additions by the wife of an American Homoeopathic Physician. Designed chiefly for the Use of such Persons as are under Homoeopathic Treatment. Pp. 176. Price,..........................$0.50 ‘HULL’S J AHR. A New Manual of Homoeopathic Practice. Edited, with Annotations and Additions, by F. G. SNELLING, M.D. Sixth American edition. With an Appendix of the New Remedies, by C. J. HEMPEL, M.D. In two volumes. Vol. I, price $5.00. Vol. II, price, $4.00. The complete work, 2,076 pages, . . . . . . . . . . . . $9.00 The first volume, containing the symd/otomatology, gives the complete patho- genesis of two hundred and eighty-seven remedies, besides a large number of new remedies added by Dr. Hempel in the appendix. The second volume contains an admirably arranged Repertory. Each chapter is accompanied by copicns clinical remarks and the concomitant symptoms of the chief remedies for the malady treated of, thus imparting a mass of information and rendering the work indispensable to every student and practitioner of medicine. JAHR, DR. G. H. G. Therapeutic Guide; the most important re- sults of more than Forty Years’ Practice. With Personal Observations re- garding the truly reliable and practically verified Curative Indications in actual cases of disease. Translated, with Notes and New Remedies, by C.J.HEMPEL,M.D. Pp.546,. . . . . . . . . . . . . . . $3.00 “With this characteristically long title, the veteran and indefatigable Jahr gives us another volume of homoeopathics. Besides the explanation of its purport contained in the title itself, the author’s preface still further sets forth its distinctive aim. It is intended, he says as a ‘guide to beginners, where I only indicate the most important and decisive points for the selection of a remedy, and where I do not offer anything but what my own individual experience, during a practice of forty years, has enabled me to verify as absolutely decishe in choosing the proper remedy. The reader will easily comprehend that, in carrying out this plan, I had rigidly to exclude all cases concerning which I had no experience of my own to offer.’ . . . We are bound to say that the book itself is agreeable, chatty, and full of practical observation. It may be read straight through with interest, and referred to in the treatment of particular cases with advantage.”——British Journal of Homcropatky. J AHIR, DR. G. H. G. The Homoeopathic Treatment of Dis- eases of Females and Infants at the Breast. Translated from the French, by C. J . HEMPEL, M. D. Pp. 422. Half leather, $2.00 This work deserves the most careful attention on the part of homoeopathic practitioners. The diseases to which the female organism is subject are de- scribed with the most minute correctness, and the treatment is likewise indi- STANDARD HoMcEoPATHIo PUBLICATIONS. 17 cated with a care that would seem to defy criticism. No one can study this work without deriving both profit and pleasure. JONES, DR. SAMUEL A. The Grounds of a Homoeopath’s Faith. Three lectures, delivered at the request of Matriculates of the Department of Medicine and Surgery (Old School) of the University of Michigan. By SAMUEL A. JONES, M.D., Professor of Materia Medica, Thera- peutics, and Experimental Pathogensy in the Homooepathic Medical Col- lege of the University of Michigan, etc., etc. Pp. 92. 12mo. Cloth (per dozen,$3),”........................$0.30 The first Lecture is on The Law of Similars; its Claim to be a_ Science in that it enables Precision. The second Lecture, The Single Remedy a Necessity of Science. The third Lecture, The illinimnm Dose an Inevitable Sequence. A fourth Lecture, on The Dynamization Theory, was to have finished the course, but was prevented by the approach of final examination, the preparation for which left no time for hearing evening lectures. The Lectures are issued in a convenient size for the coat-pocket. JOHNSON, DR. I. 1). Therapeutic Key. Sixteenth Edition. Pp. 400. Bound in flexible leather cover, . . . . . . . .8225 Boundincloth, 1.75 Again we have the pleasure of announcing a new edition of the above, which, since its first appearance, has been a leading work of reference for the clinical student and busy practitioner of the homoeopathic school. Notwith- standing the many editions through which it has passed, there is still a de- mand for the book; and each time it appears, it is found laden with newer and more valuable material. In this edition the author has reproduced the Com- parative Materia Medica, which was omitted in the previous. This will no doubt be very acceptable to many, as its nonappearance in the last edition gave rise to expression of disappointment from various quarters. Besides this, the author has introduced other new matter and further indications for the use of remedies, which makes the book still more desirable. “ This is a wonderful little book, that seems to contain nearly everything pertaining to the practice of physio; and all neatly epitomized, so that the book may be carried very com- fortably in the pocket, to serve as a source for a refresher in a case of need. “It is a marvel to us how the author has contrived to put into 347 pages such a vast amount of information, and all of the very kind that is needed. N o wonder it is in its tenth edition.——Homoeopathic World, London-—notice of tenth edition. JOHNSON, DR. I. D. A Guide to Homoeopathic Practice. Designed for the Use of Families and Private Individuals. Pp. 494. Cloth,.................... $2.00 This is the latest work on Domestic Practice issued, and the well and favor- 2 18 STANDARD HoMcEoPATHIo PUBLICATIONS. ably known author has surpassed himself. In this book fifty-six remedies are introduced for internal application, and four for external use. The work con- sists of two parts. Part I is subdivided into seventeen chapters, each being de- voted to a special part of the body, or to a peculiar class of disease. Part II contains a short and concise Materia Medica. The whole is carefully written with a view of avoiding technical terms as much as possible, thus insuring its comprehension by any person of ordinary intelligence. “Family Guides are often of great service, not only in enabling individuals to re- lieve the trifling maladies of such frequent occurrence in every family, but in the graver forms of disease, by prompt action to prepare the way for the riper intelligence of the phy- S1C1&I'l. “The work under notice seems to have been carefully prepared by an intelligent phy- sician, and is one of the handsomest specimens of book-making we have seen from its pub- lisher.”--—Homoeopathic Times. JOHNSON, DR. I. D. A Guide to Homoeopathic Practice. Designed for the Use of Families and Private Individuals. Translated into German. Pp.463. Price, . . . . . . . . . . . . . . . . . $2.00 This valuable domestic homoeopathic guide, which has become so popular in English, has now been published in German, under the belief that in time the translation will be equally in demand. A work of such practical usefulness cannot fail to win its way to the German homoeopathic household. LAURIE and McCLATCHEY. The Homoeopathic Domestic Medicille. By Josnrn LAURIE, M. D., Ninth American, from the Twenty-first English edition. Edited and revised, with numerous and im- portant additions, and the introduction of the new remedies. By R. J. MOCLATCHEY, M. D. Pp. 1044. 8vo. Half morocco, . . . . . $5.00 “ We do not hesitate to indorse the claims made by the publishers, that this is the most complete, clear‘, and comprehensive treatise on the domestic homoeopathic treatment of disease extant. This handsome volume of nearly eleven hundred pages is divided into six parts Part I is introductory, and is almost faultless. It gives the most complete and exact directions for the maintenance of health, and of the method of investigating the condition of the sick, and of discriminating between different diseases. It is written in the most lucid style, and is, above all things, wonderfully free from technicalities. Part II treats of symptoms, character, distinctions, and treatment of general diseases, together with a chapter on casualties. Part III takes up diseases peculiar to women. , Part IV is devoted to the disorders of infancy and childhood. Part V gives the characteristic symptoms of the medicines referred to in the body of the work, while Part VI introduces the repertory." -—-Ha/memannian Monthly. LILIENTHAL, DR. S. Homoeopathic Therapeutics. By S. LILIENTHAL, M. D., Editor of North-American Journal of Homoeopathy, Professor of Clinical Medicine and Psychology in the New York Homoe- opathic Medical College, and Professor of Theory and Practice in the STANDARD Ho1\IoaoPATHIc PUBI.IcATIoNs. 19 G New York College Hospital for Women, etc. Second edition. Pp. 835. 8vo. Half morocco, $6.00; Cloth, . . . . . . . . . . . . . $5.00 “Certainly no one in our ranks is so well qualified for this work as he who has done it, and, in considering the work done, we must have a true conception of the proper sphere of such a work. For the fresh graduate this book will be invaluable, and to all such we unhesitatingly and very earnestly commend it. To the older one, who says he has no use for this book, we have nothing to say. He is a good one to avoid when well, and to dread when ill.”—Prof. Samuel A. Jones in American Observer. “ . . . It is an extraordinarily useful book, and those who add it to their library will never feel regret, for we are not saying too much in pronouncing it the best work on thera- peutics in homoeopathic (or any other) literature. With this under one elbow, and Hering’s or Allen’s Materia Medica under the other, the careful homoeopathic practitioner can refute Niemayer’s too confident assertion,‘ I declare it idle to hope for a time when a medical prescription should be the simple resultant of known quantities.’ Doctor, by all means buy Lilienthal’s Homoeopathic Therapeutics. It contains a mine of wealth.”—Prof. Chas. Gatchel in Ibid. LUTZE, DR. A. Manual of Homoeopathic Theory and Practice. Designed for the use of Physicians and Families. Trans- lated from the German, with additions by C. J. HEMPEL, M. D. From the sixtieth thousand of the German edition. Pp. 750. 8vo. Half leather,.........................$2.50 MALAN, H. Family Guide to the Administration of Ho- moeopathic Remedies. Pp. 112. 32mo. Cloth, . . . . $0.30 MANUAL OF HOM(EOPATHIC VETERINARY PRAC- TICE. Designed for all kinds of Domestic Animals and Fowls, prescrib- ing their proper treatment when injured or diseased, and their particular care and general management in health. Second and enlarged edition. Pp. 684. 8vo. Half morocco, . . . . . . . . . . . . . . . $5.00 “ In order to rightly estimate the value and comprehensiveness of this great work, the reader should compare it, as we have done, with the best of those already before the public. In size, fullness, and practical value it is head and shoulders above the very best of them, while in many most important disorders it is far superior to them altogether, con- taining, as it does, recent forms of disease of which they make no mention.” ——-.Hahneman- niun Monthly. MARSDEN, DR. J. H. Handbook of Practical Midwifery, WITH FULL INsTRUoTIoNs FOR THE HOMCEOPATHIO TREATMENT on THE DIsEAsEs OF PREGNANCY, AND THE AocIDENTs AND DIsEAsEs INCIDENT To LABOR AND THE PUERPERAL STATE. J. H. MARsDEN, A. M., M. D. PP‘ I D O I O O O O I O O I l I O U I I I O I I “ It is seldom we have perused a text-book with such entire satisfaction as this. The author has certainly succeeded in his design of furnishing the student and young prac- titioner, within as narrow limits as possible, all necessary instruction in practical midwifery. 20 STANDARD HOMCEOPATHIO PUBLICATIONS. The work shows on every page extended research and thorough practical knowledge. The style is clear, the array of facts unique, and the deductions judicious and practical. We are particularly pleased with his discussion of the management of labor, and the management of mother and child immediately after the birth, but much is left open to the common sense and practical judgment of the attendant in peculiar and individual cases.”—Hbmoeo- patlric Times. MORGAN, DR. W. The Text-book for Domestic Practice; being plain and concise directions for the Administration of Homoeopathic Medicines in Simple Ailments. Pp. 191. 32mo. Cloth, . . . . $0.50 This is a concise and short treatise on the most common ailments, printed in convenient size for the pocket; a veritable traveler’s companion. NEIDHARD, DR. C. Pathogenetic and Clinical Repertory of the most Prominent Symptoms of the Head, with their concomitants and conditions. By Dr. C. NEIDHARD, formerly Professor of Clinical Medicine in the Homoeopathic Medical College of Pennsylvania. Pp. 188. 8vo. Cloth, . . . . . . . . . . . $1.50 “We trust that the volume will find its way into the library of a large number of physicians, and we have no doubt it will be found worthy of a place. The salient advan- tages of the book are as follows: “ 1. It furnishes us with the most essential head symptoms of the Materia Medica. 2. It gives the confirmation of these, as well as other symptoms, from the experience of an ex- tensive practice covering a period of fifty years. 3. To these are added the concomitants in other parts of the body, produced by the same remedy, and the conditions under which these symptoms are aggravated or ameliorated. It is the author’s experience that if the symptoms of the head are most similar to any remedy, this remedy is also most eflicacious to the corresponding symptoms in other parts of the body. 4. The different parts of the head affected are divided and classified in difi'erent chapters, for the purpose of affording easy reference to the student or practitioner. To all of them the concomitants and condi- tions are appended.”—-New York Medical Times. ._ “The Repertory, as a whole, is excellently planned and executed, and is doubtless des- tined to prove of genuine usefulness ”-»New England Medical Gazette. NORTON, DR. GEO. S. Ophthalmic Therapeutics. By Gno. S. NQRTON, M. D., Professor of Ophthalmology in the College of the New York Ophthalmic Hospital, Senior Surgeon to the New York Ophthalmic Hospital, etc. With an introduction by PROF. T. F. ALLEN, M. D. Sec- ond edition. Re-written and revised, with copious additions. Pp. 342. 8vo. Cloth,.........................$2.50 The second edition of Allen and Norton’s Ophthalmic Therapeutics has now been issued from the press. It has been re-written, revised, and consider- ably enlarged by Professor Norton, and will, without doubt, be as favorably re- ceived as the first edition—-out of print since several years. This work embodies the clinical experiences garnered at the N. Y. Ophthalmic Hospital, than which STANDARD HOMCEOPATHIC PUBLICATIONS. 21 a better appointed and more carefully conducted establishment does not exist in this country. Diseases of the eye are steadily on the increase, and no physician can afford to do without the practical experience as laid down in the sterling work under notice. PERKINS, DR. D. C. The Homoeopathic Therapeutics of Rheumatism and kindred Diseases, with Notes, Suggestions, andaComplete Repertory. By D. C. PERKINS, M. D. Pp. 180. 8vo. Cloth,..........................1.50 This is a work which presents, in a most distinct and interesting manner, the symptoms which should guide in the selection of the remedy for all forms of rheumatism; and its excellence has been heartily acknowledged by our medical press. “ It is seldom that we can say, with truth, that a long-felt want has been supplied; but in reference to Dr. Perkins’ book we do say it.”—--The Homoeopathic Physician. PETERS, DR. J. C. A Treatise on the Principal Diseases of the Eyes. Based on Th. J. B.1'ickert’s Clinical Experiences in Homoeop- athy. Pp. 29l. 8vo. Cloth, . . . . . . . . . . . . . $1.50 RAUE, DR. C. G. Special Pathology and Diagnostics, with Therapeutic Hints. By. Dr. C. Cr. RAUE. Third edition, re- written and enlarged. Pp. 1,094. Large 8vo. Half morocco or sheep, . . . . . $8.00 This is a book which has made for itself a name and a place in the litera- ture of our homoeopathic school of medicine, and, in connection with this Third Edition, it is enough to say that the work has been greatly improved and con- siderably enlarged, and, as Homoeopathy now stands, is doubtless as near. as possible to all that can be desired. Practitioners who own the first and second editions will find it to their interest to own also the third, with its new and valuable features. “The third edition of this classical work will be welcomed by every homoeopathic practitioner. . . . We know of no book in either school of medicine at once so concise and accurate.” -—-Calijfornia Homoeopath. “ By the revision and enlargement of this excellent work the author has again con- ferred aboon upon the entire homoeopathic school. As a work on practice, this book is undoubtedly the best representative of Homoeopathy to be found in our literature. Its aeti- ology, pathology, diagnosis, are clear and concise, and the ‘ Therapeutic Hints,’ with ‘ Di- gest,’ enable the practitioner to cure his patient. . . . The ofiice of every homoeopath will be incomplete without this work for reference. It will repay its cost many times a year.” —Medical Advance. “The young physician of limited means, and consequent limited library, would find it to his special advantage to possess it, as it really stands as a fair equivalent to many mono- graphs on many subjects ordinarily considered desirable possessions ”~—Medical Era: 22 STANDARD HOMCEOPATHIC PUBLICATIONS. “Prof. Raue, as a teacher, was always noted for his practical conciseness in stating things, and his statements have always been looked upon as eminently reliable, hence it is no wonder that his work should reach a third edition.”-—-N. Y. Medical Times. “ To the general practitioner, no matter how ‘ busy,’ to the student, to those who are seeking light in this new and rapidly enlarging field of medicine, and to the old school phy- sician we recommend this work as one far superior to any now in existence, taking the size into consideration.”-—.Physicians’ and Surgeons’ Medical Investigator. REIL, DR. A. Monograph on Aconite. Its Therapeutic and Physiological Effects, together with its Uses, and Accurate Statements de- rived from the various Sources of Medical Literature. By A. REIL, M. D. Translated from the German by H. B. Millard, M. D. Prize essay. Pp.168,........ .......$0.60 RUSH, DR. JOHN. Veterinary Surgeon. The Handbook to Veterinary Homoeopathy; or, the Homoeopathic Treatment of Horses, Cattle, Sheep, Dogs, and Swine. From the London edition. With nu- merous additions from the Seventh German edition of Dr. F. E. Gunther’s “ Homoeopathic Veterinary.” Translated by J. F. SHEEK, M. D. Pp. 150. 18mo.Cloth,........ . ......$0.50 SCHZEFER, DR. J. C. New Manual of Homoeopathic Veter- inary Medicine. An easy and comprehensive arrangement of Diseases, adapted to the use of every owner of Domestic Animals, and especially de- signed for the farmer living out of the reach of medical advice, and show- ing him the way of treating his sick Horses, Cattle, Sheep, Swine, and Dogs in the most, simple, expeditious, safe, and cheap manner. Trans- lated from the German, with numerous additions from other veterinary manuals, by C. J. HEMPEL, M. D. Pp. 321. 8vo. Cloth, . . . . $2.00 SCHUSSLER, DR. MED. An Abbreviated Therapy; The Biochemical Treatment of Disease. By DR. MED. Scniissrmn, of Oldenburg. Translated from the Twelfth German edition by DR. J. ‘ T. O’CONNoR. Pp. 94. 12mo. Cloth, . . . . . . . . . . . . $0.90 This translation of Schiissler’s Twelve Tissue Remedies is altogether new, and the rendering is as close to the original as possible. Dr. O’Connor has also added a very useful repertory, which greatly enhances the value of the work, and many who already possess the old edition will find it to their advantage to procure also the new. SHARP’S TRACTS ON HOMUEOPATHY, each,’ 5 cents; per hundred,................ ."'...$3.00 N o. 1. What is Homoeopathy? No. 7. The Principles of Homoeopathy. N 0. 2. The Defense of Homqeopathy. £0. 8. Controversy on c: 6 ° 6 i812: i’tZ§lf.‘;‘l‘i{....r “ i.::i’i.1if::§§;;:§§ “ No. 5. The Difficulties of L‘ N 0. 11. Single Medicines of : No. 6. Advantages of N 0. 12. Common Sense of STANDARD HOMCEOPATHIC PUBLICATIONS. 23 SHARP’S TRACTS, complete set of 12 numbers, $0.50; Bound, $0.75, SMALL, DR. A. E. Manual of Homoeopathic Practice, for L"? tlFiTs‘e of FaTnilies em&Priva1eindividna1s. Fifteenth enlarged edition. Pp. 831. 8vo. Half leather, . . . . . . . . . . . . . . . . $2.50 SMALL, DR. A. E. Manual of Homoeopathic Practice. Trans-» lated into German by C. J. HEMPEL, M.D. Eleventh edition. Pp. 643. 8vo. Cloth, . ‘ . . . . . . . . . . . . . . . . . . . . . . . $2.50 STAPF, DR. E. Additions to the Materia Medica Pnra. Translated by C. J. HEMPEL, M. D. Pp. 292. 8vo. Cloth, . . . $1.50 This work is an appendix to Hahnemann’s Materia Medica Pura. Every remedy is accompanied with extensive and most interesting clinical remarks, and a variety of cases illustrative of its therapeutical uses. Taschenbuch der Homoeopathic zum Familien-Gebrauch. Pp. 233. 12mo. Cloth, . . . . . . . . . . . . . . . . . . $0.75 This is an excellent little work on homoeopathic domestic practice in the German language. TESSIER, DR. J. P. Clinical Remarks concerning the Homoeopathic Treatnlent of Pneumonia, preceded by a Re- trospective View of the Allopathic Materia Medica and an explanation of the Homoeopathic Law of Cure. Translated by C. J. HEMPEL, M. D. Pp. 131. 8vo. Cloth, . . . . . . . . . . . . . . . . . . . . . $0.75 TESTE. A Homoeopathic Treatise on the Diseases of Chil- clren. By ALPH. TESTE, M. D. Translated from the French by EMMA H. COTE. Fourth edition. Pp. 345. 12mo. Cloth, . . . . . . $1.50 Dr. Teste’s work is unique, in that in most cases it recommends for certain afi'ections remedies that are not usually thought of in connection therewith; but, embodying the results of an immense practical experience, they rarely fail to accomplish the desired end. VERDI, DR. T. S. Maternity, a Popular Treatise for Young Wives and Mothers. By TULLIO SUZZARA VERDI, A. M., M. D., of Washington, D. C. Pp. 450. 12mo. Cloth, . . . . . . . . $2.00 “N 0 one needs instruction more than a young mother, and the directions given by Dr. Verdi in this work are such as I should take great pleasure in recommending to all the young mothers, and some of the old ones, in the range of my practice.”—-George E’. Ship- man, M. D., Chicago, Ill. “Dr. Verdi’s book is replete with useful suggestions for wives and mothers, and his medical instructions for home use accord with the maxims of my best experience in, prac- tice.”--Jolm F. Gray, M.D., New York City. 24 STANDARD HOMCEOPATHIC PUBLICATIONS. VERDI, DR. T. S. Mothers and Daughters; Practical Studies for the Conservation of the Health of Girls. By TULLIO SUZZARA VERDI, A. M , M. D. Pp. 287. 12mo. Cloth, . . . . . . . . . $1.50 “ The people, and especially the women, need enlightening on many points connected with their physical life, and the time is fast approaching when it will no longer be thought singular or ‘ Yankeeish’ that a woman should be instructed in regard to her sexuality, its organs and their functions. . . . Dr. Verdi is doing a good work in writing such books, and we trust he will continue in the course he has adopted of educating the mothers and daughters. The book is handsomely presented. It is printed in good type on fine paper, and is neatly and substantially bound.”——-Hahnemannian Monthly. VERDI, CIRO DE SUZZARA, M. D. Progressive Medi- cine: AScientific and Practical Treatise on Diseases of the Digestive Organs and the Complications arising therefrom. By CIRO DE SUZZARA VERDI, M. D., late Acting Assistant Surgeon at Balfour Hospital, Profes- sor of Physiology and Pathology in the Cleveland Homoeopathic College for \Vomen. Pp. 349. 12mo. Cloth, . . . . . . . . . . . . $2.00 VON TAGEN. Biliary Calculi, Perineorrhaphy, Hospital Gangrene, and its Kindred Diseases. Pp. 154. 8vo. Cloth, ..s1.25 WILLIAMSON, DR. W. Diseases of Females and Chil- dren, and their Homoeopathic Treatment. Third enlarged edition. Pp. 256. Cloth,. . ' ' ' . . . . . . . . . . . . .$l.00 This work contains a short treatise on the homoeopathic treatment of the diseases of females and children, the conduct to be observed during preg- nancy, labor, and confinement, and directions for the management of new-born infants. WILSON, DR. T. P. Special Indications for Twenty-five Remedies in Intermittent Fever. By T. P. W1LsoN, M. D., Professor of Theory and Practice, Ophthalmic and Aural Surgery, Uni- versity of Michigan. Pp. 53. 18mo. Cloth, . . . . . . . . . $0.40 This little work gives the characteristic Indications in Intermittent Fever of twenty-five of the mostly used remedies. It is printed on heavy writing paper, and plenty of space is given to make additions. The name of the drug is printed on the back of the page containing the symptoms, in order that the student may the better exercise his memory. WINSLOW, DR. W. H. The Human Ear and its Diseases. A Practical Treatise upon the Examination, Recognition, and Treatment of Atfections of the Ear and Associate Parts, Prepared for the Instruction of Students and the Guidance of Physicians. By W. H. VVINSLOW, M.D., Ph. D., Oculist and Aurist to the Pittsburgh Homoeopathic Hospital, etc., STANDARD HOMCEOPATHIC PUBLIcA'rIoNs. 25 etc., with one hundred and thirty-eight illustrations. Pp. 526. 8vo. Cl0th,i............ ...$4.50 “It would ill become a non-specialist toIpasIs iudgméit hpoh the intrinsic merits of Dr. Winslow’s book, but even a general reader of medicine can see in it an author who has a firm grasp and an intelligent apprehension of his subject. There is about it an air of self- reliant confidence which, when not offensive, can come only from a consciousness of know- ing the matter in hand, and we have never read a medical work which would more quickly lead us to give its author our confidence in his Ministrations. This is always the conse- quence of honest and earnest and inclusive scholarship, and this author is entitled to his meed.”—Dr. S. A. Jones in American Observer. WIN TERBURN, DR. GEO. W. The Value of Vaccination: A N on-Partisan Review of its History and Results. By GEORGE WILLIAM WINTERBURN, Ph.D., M. D. Pp. 182. Price, bound in paper, $0.50; bound in cloth, . . . . . . . . . . . . $0.75 The MS. of this little work was placed in the hands of two physicians directly opposed on the question of vaccination. The first, who was in agree- ment with the position taken by the author, pronounced it a most interest- ing and exhaustive treatise; the second, while he did not assent to the con- clusions drawn, declared it to be a scholarly effort, and one that would be read with interest by many in the profession—“ Not a dull page in it,” he said. Such comment from two physicians of opposite views on this question is proof that the book is well worthy of the attention of those interested in the subject. WORCESTER, DR. S. Repertory to the Modalities. In their Relations to Temperature, Air, Water, Winds, Weather, and Sea- sons. Based mainly upon Hering’s Condensed Materia Medica, with additions from Allen, Lippe, and Hale. Compiled and arranged by SAMUEL WORCESTER, M. D., Salem, Mass., Lecturer on Insanity and its Jurisprudence at Boston University School of Medicine, etc., etc. Pp. 160. 12mo. Cloth, . . . . . . . . .$l.25 WORCESTER, DR. S. Insanity7 and its Treatment. Lec- tures on the Treatment of Insanity and Kindred Nervous Diseases. By SAMUEL WoRoEsTER, M. D. Pp. 262. 8vo. Cloth, . . . . $3.50 Dr. Worcester was for a number of years assistant physician of the But- ler Hospital for the Insane, at Providence, R. I., and was appointed shortly after as Lecturer on Insanity and Nervous Diseases to the Boston University School of Medicine. This work, comprising nearly five hundred pages, will be welcomed by every homoeopathic practitioner, for every physician is called upon sooner or later to undertake the treatment of cases of insanity among his patrons’ families, inasmuch as very many are 10th to deliver any afiiicted member to a public institution without having first exhausted all means 26 ISTANDARD Homcsorarnro Punnroarroris. within their power to effect a cure, and the family physician naturally is the first to be put in charge of the case. It is, therefore, of paramount importance that every homoeopathic practitioner’s library s_hould’contain such an indis- pensable work. ' “ The basis of Dr. Worcester’s work was a course of lectures delivered before the senior students of the Boston University School of Medicine. As now presented, with some alter- ations and additions, it makes a very excellent text-book for students and practitioners. Dr. Worcester has drawn very largely upon standard authorities and his own experience, which has not been small. In the direction of homoeopathic treatment he has received valuable assistance from Drs. Talcott and Butler, of the New York State Asylum. It is not, nor does it pretend to be, an exhaustive work; but, as a well-digested summary of our present knowledge of insanity, we feel sure that it will give satisfaction. We cordially recommend it.”-—New England Medical Gazette- Filmed by Preservation I991 A r. liflnnl It ...\a..w..».d.il.iH.Hfl.i.!..u.\..\.. , ‘hill?!’ 2! . . . .. F :1 £.._.!4 . M.’ niéi ii. 1., n 5" e . a sh. Q 1| - ,\w: 4“ , V. .I,lY< , . i. t fa ; v .. . i Y ... , . a ,.-..¢.,, n I . 1 i J . V. . v ;,.. is .<....1...| P...?H,.,... .r M, M1 J. ....\i_..mw. ,. wf \ . pr b~WIIv.